Modified sequence Experiment N duplicates Sequence Length Missed cleavages Proteins Leading proteins Gene names Protein names Phospho (STY) All Phospho (STY) Probabilities Max Score Min PEP Intensity Reporter intensity corrected 1 Reporter intensity corrected 2 Reporter intensity corrected 3 Reporter intensity corrected 4 Reporter intensity corrected 5 Reporter intensity corrected 6 Reporter intensity corrected 7 Reporter intensity corrected 8 Reporter intensity corrected 9 Reporter intensity corrected 10 Phosphoproteome Fullproteome TMT Channel Normal 1 TMT Channel Normal 2 TMT Channel Normal 3 TMT Channel Normal 4 TMT Channel Normal 5 TMT Channel Normal 6 TMT Channel Normal 7 TMT Channel Normal 8 TMT Channel Normal 9 TMT Channel Normal 10 TMT Channel Ratio 1 TMT Channel Ratio 2 TMT Channel Ratio 3 TMT Channel Ratio 4 TMT Channel Ratio 5 TMT Channel Ratio 6 TMT Channel Ratio 7 TMT Channel Ratio 8 TMT Channel Ratio 9 TMT Channel Ratio 10 Curve signal Log EC50 Curve slope Curve top Curve bottom R2 Curve RMSE Log EC50 error Curve slope error Curve top error Curve bottom error EC50 pEC50 Curve effect size Regulation (ac)AAAAAAAAAAGAAGGRGS(ph)GPGR ddPTM_PC-9_AZD4547_30min_R2 2 AAAAAAAAAAGAAGGRGSGPGR 22 1 Q86U42-2;Q86U42 Q86U42-2 PABPN1 Polyadenylate-binding protein 2 1 AAAAAAAAAAGAAGGRGS(1)GPGR;AAAAAAAAAAGAAGGRGS(1)GPGR 97.08 1.0499e-16 6967300.0 8943.8 5832.6 11162.2 12929.0 12385.0 11533.0 7499.5 9424.8 9079.2 11153.0 True False 11787.742357403296 7717.873887290462 11014.18193474809 9948.418801058779 10665.556530661373 10811.839686829015 8166.940971543432 7968.413720358458 9559.107976445839 10762.536864708993 1.0952568623533374 0.7171054542538048 1.0233815756640292 0.9243563042910676 0.9909890822891745 1.0045809666196535 0.7588304759562148 0.7403843369389392 0.8881835292746574 1.0 13.393730558815403 -7.2578767312976575 24.96825537280507 0.8252149472415307 0.9510383249148779 0.17523877223166584 0.11491297775868808 473.7408545239191 3320152.1212183675 0.04333488297601058 0.03221376807153444 5.522341613469469e-08 7.2578767312976575 0.12582337767334728 (ac)AAAAAAAAAAGAAGGRGS(ph)GPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAAAAAAAAAGAAGGRGSGPGR 22 1 Q86U42-2;Q86U42 Q86U42-2 PABPN1 Polyadenylate-binding protein 2 1 AAAAAAAAAAGAAGGRGS(1)GPGR 81.003 5.0351e-16 0.0 4117.1 6331.3 5127.7 8549.5 10509.0 5526.1 8058.0 5700.6 5265.2 4941.2 True False 4814.043713568395 6959.8296218959895 5249.963814910542 8070.499232852975 8449.836889487717 5236.301587856934 7294.687905132049 5550.965290284971 5342.193589220224 5837.000445482322 0.8247461617540791 1.192364072420571 0.899428373176478 1.3826449574968458 1.4476334152120305 0.8970877485386672 1.2497322851462067 0.9509962080919946 0.9152292584378565 1.0 12.511011462989334 -7.788480446748705 23.774882623909956 0.9498341090177511 1.1346180349061863 0.1376809907541312 0.19686359469611267 259.8159883489064 228427.9454370725 0.10857141891418806 0.05218513843479485 1.6274945887222087e-08 7.788480446748705 0.18478392588843517 (ac)AAAAAAAGDS(ph)DSWDADAFSVEDPVRK ddPTM_PC-9_AZD4547_30min_R2 2 AAAAAAAGDSDSWDADAFSVEDPVRK 26 1 O75822;O75822-2;O75822-3 O75822 EIF3J Eukaryotic translation initiation factor 3 subunit J 1 AAAAAAAGDS(0.997)DS(0.003)WDADAFSVEDPVRK;AAAAAAAGDS(0.935)DS(0.065)WDADAFSVEDPVRK 82.26700000000001 4.5856e-12 3492400.0 11093.5 7496.599999999999 8760.1 16700.7 15975.3 10266.68 9133.3 15265.2 10415.4 10130.9 True False 14621.002240865577 9919.729345996931 8643.935350252337 12850.611638242883 13757.405348750475 9624.702876612651 9946.146006453453 12906.314099399027 10965.936780539472 9776.220274605972 1.4955680038065502 1.0146794024029644 0.8841796837071297 1.3144764824522965 1.4072315232591222 0.9845014337098263 1.0173815367365309 1.3201742326657235 1.1216949365414592 1.0 13.255061076518963 (ac)AAAAAAAGDS(ph)DSWDADAFSVEDPVRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AAAAAAAGDSDSWDADAFSVEDPVRK 26 1 O75822;O75822-2;O75822-3 O75822 EIF3J Eukaryotic translation initiation factor 3 subunit J 1 AAAAAAAGDS(0.934)DS(0.066)WDADAFSVEDPVRK;AAAAAAAGDS(0.969)DS(0.031)WDADAFSVEDPVRK;AAAAAAAGDS(0.782)DS(0.218)WDADAFSVEDPVRK 81.696 1.1337999999999999e-11 7839700.0 23832.699999999997 22384.7 27893.5 32600.9 35396.9 33577.2 34516.8 30987.5 26992.4 21143.47 True False 27867.10539271853 24606.905080671448 28558.58682668783 30774.37726654385 28461.131543772743 31816.352522717607 31247.118824008667 30174.110958970185 27387.112785396203 24976.61373938356 1.1157279238689268 0.9851978069337258 1.1434130793181205 1.2321276850279457 1.1395112180036933 1.2738457204288276 1.2510550529408904 1.2080945509194916 1.096510242387731 1.0 14.60829027312646 -5.46753638999592 6.165592266869541 1.1867073063984963 1.052047000141946 0.23749263508234986 0.08248154699015484 0.25169962865623846 20.998729673307363 0.02083111103932178 0.0432473708282569 3.407717699755088e-06 5.46753638999592 -0.13466030625655034 (ac)AAAAAAAGDS(ph)DSWDADAFSVEDPVRK ddPTM_PC-9_Lapatinib_30min_R1 1 AAAAAAAGDSDSWDADAFSVEDPVRK 26 1 O75822;O75822-2;O75822-3 O75822 EIF3J Eukaryotic translation initiation factor 3 subunit J 1 AAAAAAAGDS(0.935)DS(0.065)WDADAFSVEDPVRK 67.895 1.2735e-09 2715000.0 5308.7 5697.6 6364.6 6504.6 6698.7 5214.2 4871.2 5243.8 6389.2 5124.3 True False 5232.996964503653 5684.407557259499 5841.32715606648 6982.96998270951 6304.695636150914 4991.200820893866 5123.406901035344 5487.446091433063 5669.581014741289 6010.0284272994495 0.8707108506731392 0.9458204110049002 0.9719300377238359 1.1618863483225224 1.0490292537574353 0.8304787375417816 0.8524763173770044 0.9130482755301702 0.9433534438852668 1.0 12.55315609952982 -6.7534544715863465 24.9927284438907 0.8989746791057638 1.0043204174504643 0.23210302343375788 0.08268995138950626 263.90421606340317 826018.0690477088 0.029904222730040352 0.02939014492897222 1.7641907002684216e-07 6.7534544715863465 0.10534573834470051 (ac)AAAVAAPLAAGGEEAAATTSVPGS(ph)PGLPGRR ddPTM_PC-9_AZD4547_30min_R2 2 AAAVAAPLAAGGEEAAATTSVPGSPGLPGRR 31 1 O75427 O75427 LRCH4 Leucine-rich repeat and calponin homology domain-containing protein 4 1 AAAVAAPLAAGGEEAAAT(0.004)T(0.004)S(0.015)VPGS(0.978)PGLPGRR;AAAVAAPLAAGGEEAAAT(0.013)T(0.024)S(0.07)VPGS(0.893)PGLPGRR 60.595 1.2419e-06 13642000.0 2575.6000000000004 1908.75 4164.0 1162.2 1051.5 1165.0 2879.7 1629.2 2824.4 734.36 True False 3394.5872241919474 2525.7161098593538 4108.782639290732 894.2727458110068 905.5173752111776 1092.1523658333317 3135.9877212819006 1377.444575291571 2973.692017873121 708.6502799217878 4.790215033241221 3.5641220802708373 5.798039958079476 1.2619380407352774 1.2778057116002517 1.5411725596917427 4.4252966662597135 1.9437578934472397 4.196275796576727 1.0 9.468930020486937 -5.763868440999831 24.99999261465997 2.2969488579540402 4.602125349368581 0.4590729182718081 1.2315955831938712 61.134421181660464 629208.7754484139 0.3468307964631218 0.5430241927293282 1.722390252399687e-06 5.763868440999831 2.305176491414541 (ac)AAAVAAPLAAGGEEAAATTSVPGS(ph)PGLPGRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AAAVAAPLAAGGEEAAATTSVPGSPGLPGRR 31 1 O75427 O75427 LRCH4 Leucine-rich repeat and calponin homology domain-containing protein 4 1 AAAVAAPLAAGGEEAAAT(0.039)T(0.012)S(0.039)VPGS(0.909)PGLPGRR;AAAVAAPLAAGGEEAAAT(0.002)T(0.016)S(0.053)VPGS(0.929)PGLPGRR 71.874 3.1911e-07 9188200.0 1277.4 571.34 1655.67 1618.43 1743.3 2271.4 3314.03 1951.9 632.84 627.71 True False 1493.6385901999631 628.0588593454825 1695.1474519634412 1527.7546141208545 1401.71287938376 2152.283785428826 3000.101086900564 1900.664693209 642.0940877843442 741.508854050374 2.0143233382058763 0.8470011597498951 2.2860785042605603 2.0603322614096085 1.890352180863555 2.902573278353075 4.045941016770049 2.5632393771523048 0.8659290907681109 1.0 9.534320109181945 -5.357739138456437 8.310660534082146 2.335093401018552 1.4332344293906132 0.08996654089021972 0.9054224419145783 0.592022360369414 45.80691499348655 0.24601513638382333 0.5140748997257387 4.3879418295065324e-06 5.357739138456437 -0.9018589716279386 (ac)AAAVAAPLAAGGEEAAATTSVPGS(ph)PGLPGRR ddPTM_PC-9_Lapatinib_30min_R1 2 AAAVAAPLAAGGEEAAATTSVPGSPGLPGRR 31 1 O75427 O75427 LRCH4 Leucine-rich repeat and calponin homology domain-containing protein 4 1 AAAVAAPLAAGGEEAAAT(0.019)T(0.019)S(0.055)VPGS(0.907)PGLPGRR;AAAVAAPLAAGGEEAAAT(0.004)T(0.008)S(0.018)VPGS(0.97)PGLPGRR 52.602 0.0010585999999999998 7817800.0 1456.3 1913.71 3409.3 2449.88 1645.4 1080.7 2040.75 5196.2 2320.3999999999996 1330.6 True False 1435.5328949472878 1909.2789220729912 3129.0005142785803 2630.052347760104 1548.6208069808647 1034.4809802347447 2146.410049533561 5437.634421660721 2059.0521171047517 1560.5924370869473 0.9198640598482588 1.2234321253260163 2.005008123786166 1.6852909736442434 0.9923287914117864 0.6628770943973948 1.3753815528800846 3.48433985224918 1.3194041366420086 1.0 10.607878098232767 -7.556537063584044 24.999807115994646 2.127095650397631 1.267112101192215 0.14244146046446005 0.7104421914028265 275.824994524901 204866.7822536574 0.32642613083228766 0.18846338445997166 2.7762779027304747e-08 7.556537063584044 -0.859983549205416 (ac)AADVSVTHRPPLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 AADVSVTHRPPLSPK 15 1 A0A087WZ13;Q8IY67-2;Q8IY67;Q8IY67-3 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 AADVS(0.009)VT(0.018)HRPPLS(0.973)PK 41.367 0.009067799999999999 429810000.0 52843.0 54656.0 128860.0 210920.0 184290.0 159910.0 122640.0 192020.0 125750.0 164600.0 True False 69645.9747973191 72322.48314366622 127151.2322043717 162295.65268151587 158704.51457695512 149910.80242095116 133554.7224148395 162347.72118063312 132396.888276287 158837.40410034088 0.43847338850565887 0.4553240060381408 0.80051190035848 1.0217722557275637 0.9991633612741379 0.9438003804585563 0.8408266501917282 1.0221000657885009 0.8335372201918456 1.0 17.277191162458116 -5.3589826093052135 2.9569087278186763 0.948744859239929 0.433024808512834 0.9027532053600329 0.06530229696691253 0.06966872339858249 1.1588050869751354 0.017620724125373115 0.04530746625046033 4.375396254493315e-06 5.3589826093052135 -0.515720050727095 down (ac)AADVSVTHRPPLS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AADVSVTHRPPLSPK 15 1 A0A087WZ13;Q8IY67-2;Q8IY67;Q8IY67-3 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 AADVS(0.011)VT(0.098)HRPPLS(0.891)PK 59.68 7.1172e-05 13538000.0 8166.1 10098.0 22109.0 17352.0 20601.0 18525.0 17605.0 18473.0 16262.0 12532.0 True False 9548.459442173105 11100.462704642921 22636.162408849417 16379.823695943018 16564.38193551589 17553.516388601318 15937.326950837638 17988.103323761403 16499.800985318558 14803.952396742583 0.6449939304232105 0.749831018578892 1.5290620911365678 1.106449362776064 1.1189161847859403 1.185731750425227 1.076558916411028 1.2150878928602507 1.1145537720689458 1.0 13.853694781209851 -5.093305372174707 7.7736491914394135 1.1689498082522989 0.6705766113330102 0.6671129140627421 0.13392524611064258 0.13706318833500608 9.995165573614626 0.032591275183506616 0.08761267395688149 8.06667626143814e-06 5.093305372174707 -0.4983731969192887 (ac)AADVSVTHRPPLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 AADVSVTHRPPLSPK 15 1 A0A087WZ13;Q8IY67-2;Q8IY67;Q8IY67-3 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 AADVS(0.047)VT(0.165)HRPPLS(0.788)PK 41.227 0.017495 366090000.0 36969.0 32098.0 53588.0 37468.0 38616.0 49908.0 36955.0 38545.0 53132.0 32081.0 True False 36441.8152807157 32023.679053095228 49182.20149566199 40223.52170958396 36344.68280197706 47773.55118123029 38868.34907779627 40335.94141544061 47147.71465523603 37626.15810475449 0.9685234187146752 0.8511014854064698 1.3071279124149342 1.0690307949485085 0.9659419040548948 1.2696898537508021 1.0330140262947765 1.0720186021422078 1.2530568367881914 1.0 15.199448367169909 -5.236027814533241 24.901859426611693 1.1185476970273043 0.9098124183979189 0.35007862220311314 0.11518164994151972 787.4513067776381 771653.7322359488 0.02813411400022592 0.07437000437446817 5.807272234638323e-06 5.236027814533241 -0.20873527862938535 (ac)AAGGAAPETPAIS(ph)PSKR ddPTM_PC-9_AZD4547_30min_R2 2 AAGGAAPETPAISPSKR 17 1 H0YNW5;H0YMM5 H0YNW5 DUT 1 AAGGAAPET(0.002)PAIS(0.969)PS(0.029)KR;AAGGAAPET(0.004)PAIS(0.833)PS(0.163)KR 114.56 8.288e-05 26620000.0 45214.0 31996.0 42021.0 64258.0 53298.0 51729.0 49828.0 52999.0 43795.0 46432.0 True False 59591.11149037691 42338.081284117856 41463.77408396633 49444.31087620349 45898.49269044729 48494.37745252563 54262.59547037352 44809.22234586175 46109.91429073546 44806.42981280087 1.329967858170038 0.9449108411673134 0.9253978560041496 1.1035092749585154 1.0243729054559583 1.0823084466924242 1.2110448365799298 1.0000623243822941 1.0290914603859422 1.0 15.45141815632851 -5.6215477424941795 0.00753222767032373 2.8164288048933087e-07 2.146393088422584 0.050866715533350315 0.11469999797118766 44031.732639964415 69.9629487039576 9570.858125256143 10372.848714352478 2.390299152553296e-06 5.6215477424941795 2.1463928067797036 (ac)AAGGAAPETPAIS(ph)PSKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AAGGAAPETPAISPSKR 17 1 H0YNW5;H0YMM5 H0YNW5 DUT 1 AAGGAAPET(0.002)PAIS(0.816)PS(0.182)KR;AAGGAAPET(0.007)PAIS(0.843)PS(0.15)KR 101.08 2.4686e-05 21663900.0 43358.0 35774.0 39064.0 47228.0 51082.0 40800.0 54071.0 49810.0 39100.0 26420.0 True False 50697.65304046505 39325.406297870424 39995.433911045 44581.96827524189 41072.848795205195 38660.376175704914 48949.003439860375 48502.540278057444 39671.76353006738 31209.736859395078 1.6244178305272547 1.26003645833471 1.2815050024686498 1.4284634463946582 1.3160267572983724 1.2387280402227092 1.568388854426539 1.5540836020684585 1.271134188307806 1.0 14.929708572972988 -8.537959051734388 21.890782771970027 0.9999999933050159 1.3979161534902627 0.47708359649484944 0.13049691781770692 432.92619786699436 628442.8726058627 0.12883455399629584 0.03326493879635127 2.8976167820269956e-09 8.537959051734388 0.3979161601852468 (ac)AAGGAAPETPAIS(ph)PSKR ddPTM_PC-9_Lapatinib_30min_R1 2 AAGGAAPETPAISPSKR 17 1 H0YNW5;H0YMM5 H0YNW5 DUT 1 AAGGAAPET(0.148)PAIS(0.723)PS(0.129)KR;AAGGAAPET(0.093)PAIS(0.762)PS(0.145)KR 103.39 8.253399999999999e-05 23538000.0 77895.0 65819.0 73679.0 68167.0 65367.0 60236.0 54875.0 57292.0 63407.0 55354.0 True False 76784.20301580652 65666.60014940737 67621.3970291649 73180.22857844569 61522.241576466644 57659.84669697421 57716.158994562866 59953.99547472888 56265.43595468932 64921.86514543127 1.1827171453531482 1.0114712508999522 1.0415812435099703 1.1272046546185155 0.9476351524813845 0.8881421777980433 0.8890095635002642 0.9234792521814664 0.8666638863293482 1.0 15.986416827331379 -6.394617354123868 4.553233048854064 0.9081100969767943 1.0809501268525772 0.7002444982108723 0.05506207566039322 0.12800639380824122 4.172000161740777 0.016903036708435605 0.01918218389062197 4.030720144707933e-07 6.394617354123868 0.17284002987578284 (ac)AAGGDHGS(ph)PDSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AAGGDHGSPDSYR 13 0 A0A1B0GTG9;A0A1B0GWF8;A0A1B0GWJ0;A0A1B0GTJ7;A0A0A6YY92;P30566-2;P30566;B4DEP1;A0A1W2PRX2;A0A096LP72;A0A096LNY4;A0A096LNY5 A0A1B0GTG9 ADSL Adenylosuccinate lyase 1 AAGGDHGS(0.962)PDS(0.038)YR;AAGGDHGS(0.94)PDS(0.06)YR 86.944 0.00033306 9728800.0 1048.8 1859.72 3080.1 1788.3000000000002 2832.7 1279.4 2323.11 2541.29 2792.0 1120.0 True False 1226.3411252557705 2044.3407111386937 3153.5412653442963 1688.1073487468254 2277.6527697070946 1212.3060117450218 2103.0482029400982 2474.5838302193247 2832.827718054941 1323.047134084879 0.9269066034476559 1.5451760247020352 2.3835441565923707 1.275923816511987 1.721520504469778 0.9162984299750937 1.5895489652337502 1.8703670991517147 2.1411389247400794 1.0 10.369648743783765 -7.531785122721039 22.681369968493588 1.749443830776454 1.4891717777873892 0.02863321717764733 0.477130861506888 221.4866079418442 564019.300824205 0.22450148948465765 0.12998012490637373 2.9391034819655985e-08 7.531785122721039 -0.26027205298906475 (ac)AAGGDHGS(ph)PDSYR ddPTM_PC-9_Lapatinib_30min_R1 1 AAGGDHGSPDSYR 13 0 A0A1B0GTG9;A0A1B0GWF8;A0A1B0GWJ0;A0A1B0GTJ7;A0A0A6YY92;P30566-2;P30566;B4DEP1;A0A1W2PRX2;A0A096LP72;A0A096LNY4;A0A096LNY5 A0A1B0GTG9 ADSL Adenylosuccinate lyase 1 AAGGDHGS(0.967)PDS(0.033)YR 60.901 0.0013666 0.0 0.0 1504.7 1375.7 1040.6 957.91 792.1 731.77 1146.4 1314.5 683.14 True False 0.0 1501.2159595984917 1262.5952563555686 1117.129195339839 901.5676171235202 758.2237294752854 769.657470021891 1199.6659291389572 1166.4471677013437 801.2198387731675 0.0 1.8736629910427112 1.5758412301533395 1.394285489798148 1.1252437514577844 0.9463366891117949 0.9606071052863532 1.4972993316988914 1.4558390984020246 1.0 9.6460543335231 -4.745545647525614 24.999002194314897 1.31209248642552 3.31466809745812e-06 0.6502369760750075 0.2891849361953234 632.9166296178191 995450.5770572766 0.07801528448767152 1.9702241654855597 1.796612233166512e-05 4.745545647525614 -1.3120891717574223 (ac)AAGVEAAAEVAATEIK ddPTM_PC-9_Lapatinib_30min_R1 2 AAGVEAAAEVAATEIK 16 0 A0A087X0X3;P52272-2;P52272;M0R2T0;M0R019;M0QYQ7;M0R0N3;M0R0Y6 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 ; 150.09 1.9396e-12 7672400.0 28681.95 30148.7 28030.7 30474.2 31462.74 26078.97 30288.0 26657.5 26885.4 25775.56 False True 28272.940133374545 30078.892537480602 25726.124047631052 32715.374326951092 29612.163491326806 24963.63324614832 31856.164439677825 27896.10476798826 23857.283136186918 30230.831202225178 0.9352352882474988 0.9949740493826252 0.8509896362273178 1.0821857364127996 0.9795352067311721 0.8257673458978807 1.053764093569912 0.9227700218158386 0.7891705979434291 1.0 14.883733026224046 -8.001744007996312 24.99948225826238 0.8817136272384395 0.959905005564558 0.08056749693760135 0.08854221072096831 131.4036943180657 1883588.725838372 0.04724411509251223 0.022173797904174293 9.959923254344046e-09 8.001744007996312 0.07819137832611855 (ac)AALGHLAGEAAAAPGPGT(ph)PCASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AALGHLAGEAAAAPGPGTPCASR 23 0 A0A3B3IRR6;A0A3B3IT54;A0A3B3ITA3;Q9H7E9;Q9H7E9-2 A0A3B3IRR6 C8orf33 UPF0488 protein C8orf33 1 AALGHLAGEAAAAPGPGT(0.966)PCAS(0.034)R;AALGHLAGEAAAAPGPGT(0.986)PCAS(0.014)R 120.33 2.9443999999999998e-109 0.0 1176.2 0.0 1637.0 2141.86 1197.1 1965.64 1439.8 1363.3 1285.4 1396.7 True False 1375.307428991074 0.0 1676.032288357071 2021.8585282038102 962.5368484542535 1862.5583780885443 1303.4117207506972 1327.514819535751 1304.1965432621137 1649.9106537288844 0.8335647908465875 0.0 1.0158321510132384 1.225435161373317 0.5833872557152533 1.1288843876964276 0.789989274755526 0.8045980044649679 0.7904649505199335 1.0 10.688172186156033 -5.287342239902706 24.98760834650007 0.912431012154319 0.41678224408050024 0.37762506352923375 0.2569755875175104 634.5633128577757 612140.6481813161 0.06357120849411818 0.13240460922872443 5.160095746303811e-06 5.287342239902706 -0.49564876807381875 (ac)AALGHLAGEAAAAPGPGT(ph)PCASR ddPTM_PC-9_Lapatinib_30min_R1 1 AALGHLAGEAAAAPGPGTPCASR 23 0 A0A3B3IRR6;A0A3B3IT54;A0A3B3ITA3;Q9H7E9;Q9H7E9-2 A0A3B3IRR6 C8orf33 UPF0488 protein C8orf33 1 AALGHLAGEAAAAPGPGT(0.999)PCAS(0.001)R 109.68 6.7665e-14 5279500.0 1127.6 1224.9 1342.4 1378.3 1691.0 0.0 0.0 1195.3 0.0 917.79 True False 1111.5202172234854 1222.0638193076315 1232.0330538138512 1479.6647798740137 1591.5387046339147 0.0 0.0 1250.8380016571848 0.0 1076.4287786216967 1.032599870329295 1.1352946368383163 1.1445560340660872 1.3746053703326633 1.478536003721292 0.0 0.0 1.1620257898147324 0.0 1.0 10.072037152120384 -6.754192571997443 24.99999172285665 0.41550642785339353 1.2306240383332034 0.5073875191234312 0.39430467325143476 139.10359308059802 479878.1758437292 0.12998898931569408 0.12744168373079706 1.7611949357936832e-07 6.754192571997443 0.8151176104798099 (ac)AALHTT(ph)PDSPAAQLER ddPTM_PC-9_Lapatinib_30min_R1 1 AALHTTPDSPAAQLER 16 0 A6NFI3 A6NFI3 ZNF316 Zinc finger protein 316 1 AALHT(0.216)T(0.581)PDS(0.203)PAAQLER 106.6 7.1682e-12 11293000.0 1714.0 1246.7 1704.9 1122.3 1744.4 1212.6 1954.3 1110.3 1873.2 744.8 True False 1689.558045690896 1243.8133427470193 1564.7297031043174 1204.8376858830482 1641.7978216223541 1160.739924708662 2055.484091536661 1161.8885913494285 1662.2204903295221 873.5376876163821 1.9341558694521637 1.4238805725039827 1.7912560903628412 1.3792623981349708 1.8794813834561845 1.3287805908820802 2.353057138433775 1.3300955503360914 1.9028606480221992 1.0 9.770726137409424 -10.943493744390162 4.126501611963381 0.997195248691099 1.6898324837928937 0.30306662395131656 0.3190844150209654 212020390.92596173 21143.51753429149 5650410.728515244 0.07001917473084662 1.138954187337906e-11 10.943493744390162 0.6926372351017948 (ac)AALHTTPDS(ph)PAAQLER ddPTM_PC-9_AZD4547_30min_R2 3 AALHTTPDSPAAQLER 16 0 A6NFI3 A6NFI3 ZNF316 Zinc finger protein 316 1 AALHT(0.023)TPDS(0.977)PAAQLER;AALHT(0.001)T(0.001)PDS(0.998)PAAQLER;AALHT(0.021)T(0.002)PDS(0.978)PAAQLER 121.45 1.0387999999999998e-46 96129000.0 4723.6 3734.4 4449.3 5614.5 3343.6000000000004 5325.5 2357.0 4028.8 8957.5 7317.7 True False 6225.606543016415 4941.471769827778 4390.299374879022 4320.163768160301 2879.398854737133 4992.4956431291 2566.7684338859763 3406.241532613971 9430.975162901317 7061.509550334527 0.8816254511362216 0.6997755557228814 0.6217225004915612 0.6117904022314379 0.40775967719263745 0.70700118827887 0.36348721411335905 0.48236733354734407 1.3355466130403435 1.0 12.785760908383311 -8.2578791011076 24.999942741071745 1.1677733351762856 0.5912708082967142 0.6632828503012972 0.16264639630457997 168.96317491398796 1186465.4716841977 0.12186666590646185 0.041930686058696265 5.522311479850695e-09 8.2578791011076 -0.5765025268795714 (ac)AALHTTPDS(ph)PAAQLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AALHTTPDSPAAQLER 16 0 A6NFI3 A6NFI3 ZNF316 Zinc finger protein 316 1 AALHT(0.023)T(0.007)PDS(0.97)PAAQLER;AALHT(0.001)T(0.007)PDS(0.992)PAAQLER;AALHT(0.272)T(0.044)PDS(0.684)PAAQLER;AALHT(0.256)T(0.02)PDS(0.723)PAAQLER 119.04 8.2664e-37 77845000.0 1069.2 4079.9 5391.13 4295.6 7089.800000000001 8005.4 6258.1 7921.8 10090.699999999999 6693.67 True False 1250.1944423374043 4484.925508880239 5519.674985174377 4054.931458523103 5700.604584555148 7585.582731298725 5665.287463279583 7713.861143840904 10238.257397771129 7907.179383937433 0.1581087745242048 0.5671966312021292 0.6980586524174462 0.5128164243700164 0.7209403388691675 0.9593285244935765 0.7164738762330335 0.9755515550223594 1.2948052523721703 1.0 12.94894743896707 -5.572837140666204 0.3437469709452857 1.1232006121135334 4.337332586834774e-15 0.7365630476321479 0.15377397788841873 2.1498121864651187 0.3067242295133572 0.16646814999554768 0.9605485288717922 2.674008967281951e-06 5.572837140666204 -1.123200612113529 down (ac)AALHTTPDS(ph)PAAQLER ddPTM_PC-9_Lapatinib_30min_R1 3 AALHTTPDSPAAQLER 16 0 A6NFI3 A6NFI3 ZNF316 Zinc finger protein 316 1 AALHT(0.011)TPDS(0.989)PAAQLER;AALHTTPDS(1)PAAQLER;AALHT(0.058)T(0.003)PDS(0.939)PAAQLER 122.16 1.0752e-36 59638000.0 9853.0 6191.259999999999 11320.0 10567.93 9587.1 5506.05 8849.1 11553.6 11532.800000000001 5434.98 True False 9712.494413181088 6176.92451785988 10389.313296463644 11345.130825781032 9023.205626963807 5270.569076729443 9307.263099021164 12090.422434490458 10233.854618232068 6374.409051344365 1.5236697762803155 0.9690191621068254 1.629847286670838 1.7797933478066237 1.4155360213447252 0.8268325791891058 1.4600981869932332 1.8967126736149107 1.605459350945441 1.0 12.638075885737502 -7.526032652539501 24.968333762474316 1.5863326833631017 1.354800877045481 0.018449022610111943 0.3400794361616303 266.4327148440466 2109180.3270579 0.16223338748043 0.09430224585389216 2.9782924973430167e-08 7.526032652539501 -0.23153180631762083 (ac)AAPEEHDS(ph)PTEASQPIVEEEETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AAPEEHDSPTEASQPIVEEEETK 23 0 F5H1N9;Q9H0S4-2;Q9H0S4 F5H1N9 DDX47 Probable ATP-dependent RNA helicase DDX47 1 AAPEEHDS(0.688)PT(0.156)EAS(0.156)QPIVEEEETK;AAPEEHDS(0.813)PT(0.087)EAS(0.099)QPIVEEEETK 59.163000000000004 6.4179e-07 28058000.0 98329.0 104251.0 96829.0 125376.0 129476.0 110122.0 122638.0 126124.0 106996.0 89712.0 True False 114974.1576137248 114600.35030914354 99137.77058602743 118351.5891944765 104106.1072512429 104347.00846129854 111020.84081776913 122813.37863942429 108560.61408345519 105976.07544019863 1.0849067314122582 1.0813794512876778 0.9354731261205271 1.116776486606746 0.9823548080905209 0.9846279740768532 1.0476028703329103 1.15887834239273 1.024387944472571 1.0 16.69337908130511 -7.530348069488597 24.977901814935503 1.0756279964516506 1.02936542895089 0.028203329841817948 0.06460181696046663 454.0605517661691 1518382.6130611526 0.029465650681066748 0.01705292858792042 2.94884489923656e-08 7.530348069488597 -0.04626256750076063 (ac)AASAAAAS(ph)AAAASAASGSPGPGEGSAGGEKR ddPTM_PC-9_Lapatinib_30min_R1 1 AASAAAASAAAASAASGSPGPGEGSAGGEKR 31 1 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 AAS(0.007)AAAAS(0.493)AAAAS(0.44)AAS(0.019)GS(0.037)PGPGEGS(0.005)AGGEKR 47.12 6.6316e-07 16948000.0 23583.0 19348.0 22446.0 17295.0 18797.0 20174.0 16424.0 17558.0 22065.0 17255.0 True False 23246.70209540746 19303.200894737573 20600.576524065644 18566.931994428705 17691.39741632387 19311.205047890933 17274.354356750813 18373.808778630348 19579.807345249257 20237.50375915772 1.1486941458819022 0.95383309742451 1.017940590362763 0.9174516884784735 0.8741887155088629 0.9542286083160021 0.853581279703726 0.9079088506810516 0.9675011097348977 1.0 14.30474372806087 -1.522878791684272 0.8807324464885407 0.9207457362756191 97.0298665560245 0.6205719721485549 0.04923981767427698 498.8149023247943 1.1975149196492745 0.01608491511747918 96254.07745352355 0.029999996794529932 1.522878791684272 96.10912081974888 (ac)AASAAAASAAAAS(ph)AASGSPGPGEGSAGGEKR ddPTM_PC-9_AZD4547_30min_R2 1 AASAAAASAAAASAASGSPGPGEGSAGGEKR 31 1 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 AASAAAAS(0.036)AAAAS(0.48)AAS(0.48)GS(0.004)PGPGEGSAGGEKR 86.24799999999999 1.1689999999999999e-15 20548000.0 29326.0 27827.0 29684.0 63198.0 54463.0 42088.0 27732.0 45567.0 38605.0 37072.0 True False 38651.05798130654 36821.533563356286 29290.37076481896 48628.67749936673 46901.752549811084 39456.23070660366 30200.094275997417 38525.66717549167 40645.581486330484 35774.12056383858 1.0804195147811977 1.0292785114772733 0.8187586529919183 1.3593255888034848 1.311052565670073 1.1029266431915326 0.8441883070781749 1.0769144445282164 1.1361727652759157 1.0 15.126628681126586 -10.592874591517838 13.19753905806024 0.9999133664794218 1.0829281086804128 0.023841095529612444 0.16167071717132966 0.0 0.0 0.16775296572490017 0.040686070393787216 2.5534385365764606e-11 10.592874591517838 0.08301474220099103 (ac)AASAAAASAAAAS(ph)AASGSPGPGEGSAGGEKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AASAAAASAAAASAASGSPGPGEGSAGGEKR 31 1 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 AASAAAAS(0.226)AAAAS(0.767)AAS(0.007)GSPGPGEGSAGGEKR;AASAAAAS(0.001)AAAAS(0.611)AAS(0.233)GS(0.154)PGPGEGSAGGEKR 101.71 1.1925999999999999e-15 61972000.0 87022.0 78801.0 88717.0 104972.0 131878.0 116938.0 115750.0 93979.0 107200.0 81053.0 True False 101753.10583715452 86623.84250233372 90832.34974109597 99090.75916381579 106037.45259414415 110805.56542241626 104785.32204257086 91512.15082898128 108767.59719752506 95747.26728480494 1.0627259526319943 0.9047134707737073 0.948667803446658 1.0349199718574262 1.107472365542617 1.157271309820464 1.094394910832095 0.9557677563451905 1.1359864389026426 1.0 16.54694369132939 -5.937935125898403 4.200381137546584 1.077734908784289 0.9661692571191276 0.3171076350204086 0.06731683294369444 0.24278867312106744 8.687711145571946 0.019712980314456383 0.029705618484381212 1.1536255713920866e-06 5.937935125898403 -0.1115656516651613 (ac)AASAAAASAAAAS(ph)AASGSPGPGEGSAGGEKR ddPTM_PC-9_Lapatinib_30min_R1 1 AASAAAASAAAASAASGSPGPGEGSAGGEKR 31 1 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 AASAAAAS(0.027)AAAAS(0.637)AAS(0.293)GS(0.042)PGPGEGSAGGEKR 54.419 8.442100000000001e-07 19859000.0 12705.0 10902.0 13683.0 11450.0 12383.0 12131.0 10798.0 10608.0 11558.0 10089.0 True False 12523.824370188357 10876.757088816885 12558.036557907435 12292.071196080293 11654.656285914705 11612.185408742185 11357.067604980219 11100.88640640794 10256.21632886431 11832.870207252532 1.0583927779848654 0.9191985459411502 1.0612840619354076 1.0388072361806444 0.9849390791738257 0.9813498504889299 0.9597897556604071 0.9381397929645211 0.8667564292709077 1.0 13.530512438985733 -7.180775389117912 1.381938400167983 0.9284712656944687 1.0128567578779804 0.3336009092027079 0.04850911945977216 0.49194006588669 1.853658265148136 0.027773977242865195 0.017407043968712975 6.595148987096539e-08 7.180775389117912 0.08438549218351166 (ac)AASAAAASAAAASAAS(ph)GSPGPGEGSAGGEKR ddPTM_PC-9_AZD4547_30min_R2 2 AASAAAASAAAASAASGSPGPGEGSAGGEKR 31 1 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 AAS(0.001)AAAAS(0.034)AAAAS(0.433)AAS(0.454)GS(0.073)PGPGEGS(0.005)AGGEKR;AASAAAAS(0.036)AAAAS(0.297)AAS(0.507)GS(0.157)PGPGEGS(0.003)AGGEKR 64.903 1.2015e-15 163419500.0 45229.0 43698.0 60699.0 81466.0 70349.0 65021.0 53735.0 59599.0 50240.0 58877.0 True False 59610.88117835752 57822.52393903556 59894.09159997797 62685.272337153205 60582.25566213142 60955.226591286686 58517.31090151161 50389.3439987738 52895.5838330072 56815.734150764074 1.0491967070279573 1.0177202636438685 1.0541814251848842 1.1033083224941518 1.066293634460001 1.0728582056079432 1.0299490409862926 0.8868906606937886 0.9310023820627836 1.0 15.79400289445297 -7.623950730694039 5.406266895940706 0.932724393778924 1.059845075469501 0.7311248790596745 0.03280631649027735 0.10183732055830601 4.542776924601718 0.01618590147317134 0.009135693795290513 2.3771099467726336e-08 7.623950730694039 0.127120681690577 (ac)AASAAAASAAAASAAS(ph)GSPGPGEGSAGGEKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AASAAAASAAAASAASGSPGPGEGSAGGEKR 31 1 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 AASAAAAS(0.074)AAAAS(0.202)AAS(0.478)GS(0.241)PGPGEGS(0.003)AGGEKR;AASAAAAS(0.002)AAAAS(0.008)AAS(0.926)GS(0.062)PGPGEGS(0.001)AGGEKR;AASAAAAS(0.071)AAAAS(0.177)AAS(0.396)GS(0.348)PGPGEGS(0.008)AGGEKR 88.829 2.8361999999999996e-16 152405000.0 166909.8 147371.4 173312.0 208790.0 200106.0 212779.0 201560.7 207312.0 191134.6 160727.0 True False 195164.33252118167 162001.45864834735 177444.41536942057 197092.17320631325 160896.66577294053 201620.4946639784 182467.4113229023 201870.27966522117 193929.58193386233 189865.53278576816 1.0279081708916191 0.8532431151215802 0.9345793981977616 1.0380618868233402 0.8474242976711618 1.06191203693339 0.9610349421808254 1.0632276259061637 1.0214048810674856 1.0 17.534618504240996 -6.788470167945651 24.99914859491043 1.0216875590581191 0.9405296263462101 0.28729443755981476 0.06400256815015497 288.25748001019355 266589.9240297631 0.021629544102605692 0.01908022443585029 1.6275331084248842e-07 6.788470167945651 -0.08115793271190908 (ac)AASAAAASAAAASAASGS(ph)PGPGEGSAGGEK ddPTM_PC-9_AZD4547_30min_R2 1 AASAAAASAAAASAASGSPGPGEGSAGGEK 30 0 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 AAS(0.009)AAAAS(0.008)AAAAS(0.002)AAS(0.099)GS(0.881)PGPGEGSAGGEK 71.33800000000001 8.259200000000001e-07 0.0 9391.1 10121.0 10775.0 12932.0 11373.0 9511.3 10811.0 15001.0 9155.4 9367.9 True False 12377.274452985332 13392.415323057772 10632.116459740066 9950.727197408314 9794.055262269823 8916.556907425376 11773.158056317892 12682.940138686994 9639.335752880452 9039.932672366842 1.369177725274441 1.4814729056550993 1.1761278369074797 1.1007523571304438 1.0834212617764483 0.9863521367455977 1.3023501925302985 1.4029905529557818 1.0663061443306827 1.0 13.14209631243483 -5.306746421278306 6.651740819622663 1.1502733683454465 1.425126209511907 0.451946644183018 0.1254076301385522 0.19538035144258598 23.004084376085597 0.035035914896582185 0.07505785670202209 4.9346184560652344e-06 5.306746421278306 0.2748528411664606 (ac)AASAAAASAAAASAASGS(ph)PGPGEGSAGGEK ddPTM_PC-9_Lapatinib_30min_R1 1 AASAAAASAAAASAASGSPGPGEGSAGGEK 30 0 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 AAS(0.001)AAAAS(0.001)AAAAS(0.001)AAS(0.123)GS(0.873)PGPGEGSAGGEK 59.793 2.6417e-15 3827300.0 24953.0 33035.0 38235.0 31883.0 42055.0 41764.0 36381.0 42165.0 40408.0 34821.0 True False 24597.165644180226 32958.50948716435 35091.46589136817 34227.78217857011 39581.407583311215 39977.85107663909 38264.630166399846 44124.139830900356 35856.82552489606 40839.763453934 0.6022847236107299 0.8070200877715793 0.8592475304356321 0.8380994228132099 0.9691879735777076 0.9788952651925342 0.936945440674777 1.0804210431010706 0.8779880805465845 1.0 15.317686889623522 -4.037436279344892 0.5374979746797626 0.985511012469551 4.319792049494585e-15 0.7963401365447917 0.05671433435741817 3.6182593732662856 0.4389445509454047 0.02948178507652864 2.6572862596161686 9.174105300348383e-05 4.037436279344892 -0.9855110124695466 (ac)AASAAAASAAAASAASGS(ph)PGPGEGSAGGEKR ddPTM_PC-9_AZD4547_30min_R2 2 AASAAAASAAAASAASGSPGPGEGSAGGEKR 31 1 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 AAS(0.001)AAAAS(0.109)AAAAS(0.109)AAS(0.242)GS(0.539)PGPGEGS(0.001)AGGEKR;AASAAAAS(0.038)AAAAS(0.015)AAS(0.294)GS(0.651)PGPGEGS(0.003)AGGEKR 84.51 1.6139e-16 172197000.0 43209.1 44062.1 62045.9 99123.0 81336.3 70315.0 47654.0 63515.2 51435.1 49335.9 True False 56948.69499488752 58304.312143671996 61223.13082592912 76271.72378508381 70044.1587117347 65918.19193439545 51895.11368196957 53700.38527409718 54153.8543791622 47608.66515767922 1.1961834007795482 1.224657569175043 1.285966128711212 1.6020554983525153 1.4712481116567633 1.3845839137912255 1.090035049503986 1.1279540204759422 1.137478948418432 1.0 15.538936559013045 -7.262470593691862 24.878625385036706 1.0995298267369387 1.3671823313479885 0.5675217202702132 0.1160570257285308 76.26799362773387 1839970.3624548344 0.052769627010518974 0.037890758185684964 5.464235472555018e-08 7.262470593691862 0.26765250461104984 (ac)AASAAAASAAAASAASGS(ph)PGPGEGSAGGEKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AASAAAASAAAASAASGSPGPGEGSAGGEKR 31 1 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 AASAAAAS(0.001)AAAAS(0.004)AAS(0.237)GS(0.74)PGPGEGS(0.018)AGGEKR 69.16199999999999 1.2455e-15 90311000.0 63962.0 59874.0 70280.0 77189.0 95180.0 81083.0 62268.0 65807.0 67285.0 51972.0 True False 74789.50329291537 65817.89502651902 71955.74173838427 72864.35058011442 76530.1622553468 76830.86474153624 56369.52425871957 64079.63597828 68268.91583428599 61394.11218987435 1.2181869014020907 1.072055489994923 1.172030006979266 1.1868296157580374 1.2465391146737492 1.2514370189753774 0.918158472336644 1.0437423670221029 1.1119782239565554 1.0 15.905812684627522 -7.252910607869823 24.999664191945026 1.022114961032001 1.1872131223132387 0.6301268051450704 0.06475708576952187 456.357117971192 1337683.687522703 0.026446524731831525 0.020165887352883452 5.58585158156042e-08 7.252910607869823 0.16509816128123767 (ac)AASAAAASAAAASAASGS(ph)PGPGEGSAGGEKR ddPTM_PC-9_Lapatinib_30min_R1 4 AASAAAASAAAASAASGSPGPGEGSAGGEKR 31 1 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 AASAAAAS(0.003)AAAAS(0.003)AAS(0.373)GS(0.611)PGPGEGS(0.01)AGGEKR;AASAAAASAAAASAAS(0.015)GS(0.982)PGPGEGS(0.002)AGGEKR;AAS(0.002)AAAAS(0.162)AAAAS(0.164)AAS(0.198)GS(0.473)PGPGEGS(0.001)AGGEKR;AASAAAAS(0.02)AAAAS(0.16)AAS(0.374)GS(0.436)PGPGEGS(0.009)AGGEKR 98.667 3.2594e-15 344046200.0 164946.0 112676.0 154053.0 132736.0 144263.0 151965.0 111471.0 101147.0 161515.0 106497.0 True False 162593.83979260846 112415.1056447928 141387.35700177719 142497.8482343156 135777.73397197053 145465.8111977172 117242.42294820808 105846.65887527775 143323.47987164897 124904.86455166711 1.301741452394364 0.9000058248195137 1.131960372474461 1.1408510688978901 1.087049207085172 1.164612857312255 0.938653777569332 0.8474182271059114 1.1474611528229388 1.0 16.930470139756594 -7.26691728215801 24.80848702184788 0.9706681370837897 1.1108422197343024 0.24801985537505267 0.11577132395438754 582.0261165891364 2635882.3999223947 0.045491599876910635 0.03165314011718969 5.408573274564024e-08 7.26691728215801 0.14017408265051268 (ac)AASEAAVVSSPS(ph)LK ddPTM_PC-9_Lapatinib_30min_R1 1 AASEAAVVSSPSLK 14 0 Q8WWH5 Q8WWH5 TRUB1 Probable tRNA pseudouridine synthase 1 1 AASEAAVVS(0.22)S(0.335)PS(0.445)LK 79.639 7.3323e-05 1123600.0 8657.9 9815.2 11145.0 9161.7 11401.0 12135.0 9509.9 9608.7 11829.0 7992.1 True False 8534.436758335598 9792.473507444087 10228.701120944113 9835.481980535264 10730.415595228415 11616.014338066647 10002.276089701929 10055.15528028394 10496.693455107788 9373.52383619614 0.9104832832855897 1.0446950024952366 1.091233275734114 1.049283295419302 1.1447579141787207 1.2392366564654227 1.0670774688893245 1.072718804155131 1.119823626475936 1.0 13.194375794157226 -4.008577537596764 1.0307322336393288 1.1088883074420381 0.23501938856149068 0.46656189962193195 0.06042207095955004 6.737538349406155 1.82403384549737 0.019560483028812234 9.514378735324767 9.804432533817583e-05 4.008577537596764 -0.8738689188805475 (ac)AAT(ph)DLERFSNAEPEPR ddPTM_PC-9_AZD4547_30min_R2 1 AATDLERFSNAEPEPR 16 1 F8W8I8;A0A087X142;A6NMH6;A6NFQ9;Q92599-2;Q92599-4;Q92599 F8W8I8 SEPT8 Septin-8 1 AAT(0.964)DLERFS(0.036)NAEPEPR 65.241 0.005942800000000001 0.0 1070.2 1472.0 1032.9 2817.4 1532.0 1516.9 1268.1 1426.0 1582.5 3157.0 True False 1410.5013384571448 1947.7952134711034 1019.2030711151289 2167.891958396085 1319.308244244911 1422.048003203932 1380.9584433647879 1205.644466220096 1666.1477192622187 3046.474390916015 0.4629946480636703 0.6393604421159895 0.3345516621292439 0.7116068215968959 0.4330606711084878 0.46678482098657986 0.4532972433585961 0.3957507306856377 0.5469101346232689 1.0 11.572924897574751 -8.566402349546081 20.658686146087867 1.0000000014963286 0.4897982307214886 0.6793512117545295 0.10503040444544022 1358.433656436615 644786.5780635715 0.09602322445102345 0.024793089941611918 2.7139238051932608e-09 8.566402349546081 -0.5102017707748401 (ac)AATDLERFS(ph)NAEPEPR ddPTM_PC-9_AZD4547_30min_R2 1 AATDLERFSNAEPEPR 16 1 F8W8I8;A0A087X142;A6NMH6;A6NFQ9;Q92599-2;Q92599-4;Q92599 F8W8I8 SEPT8 Septin-8 1 AAT(0.219)DLERFS(0.781)NAEPEPR 73.666 2.4064000000000002e-05 5672900.0 2007.2 0.0 0.0 1914.2 2791.0 1920.3 0.0 0.0 0.0 0.0 True False 2645.447847646405 0.0 0.0 1472.9107640951902 2403.5178261668057 1800.2233374332593 0.0 0.0 0.0 0.0 0.0 (ac)AATLGAGT(ph)PPRPQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AATLGAGTPPRPQAR 15 1 A0A075B730 A0A075B730 EPPK1 1 AAT(0.001)LGAGT(0.999)PPRPQAR 58.11600000000001 0.0028983 5608700.0 6301.7 2760.4 6072.4 10564.0 8857.8 6667.2 5993.0 8254.9 7013.5 9352.9 True False 7368.453345751609 3034.434269151943 6217.189045705243 9972.133328950105 7122.1776762493355 6317.560295065189 5425.29965443737 8038.217621789525 7116.059169261575 11048.506732484337 0.6669184826658253 0.27464655112443676 0.5627175867509531 0.9025774767942599 0.6446280794950344 0.5718021854021752 0.49104370262871283 0.7275388264149678 0.6440742936182723 1.0 13.431563774033318 -14.522878745140385 0.18070357025641412 2.611605894165492 0.5269289485111475 0.386646775755743 0.15115938058326742 151.41588953178186 1.4551570922228994 87.56558162091478 0.49700098808558413 3.0000000009667556e-15 14.522878745140385 -2.084676945654344 (ac)AATLGAGT(ph)PPRPQAR ddPTM_PC-9_Lapatinib_30min_R1 1 AATLGAGTPPRPQAR 15 1 A0A075B730 A0A075B730 EPPK1 1 AAT(0.002)LGAGT(0.998)PPRPQAR 66.00399999999999 0.00058039 6073000.0 9142.1 4602.6 5313.2 5711.0 5808.4 5755.1 5811.8 5841.7 4279.0 5472.9 True False 9011.731977544188 4591.942962482904 4876.369205545111 6131.0059913375135 5466.761331753773 5508.967788793353 6112.706566644202 6113.126708174324 3797.0539601324067 6418.883472819142 1.4039407345069437 0.7153803277357432 0.7596911871346737 0.9551514710150683 0.8516685736550377 0.8582439316932858 0.9523005975304816 0.9523660515197776 0.5915443045836691 1.0 12.648106655480998 -4.752718715461182 24.986052948033254 0.8512019085636106 1.4039417882430516 0.6527340242810767 0.12152991604191504 204.57167061559204 586085.5516144427 0.029505840681924234 0.34148412313077575 1.76718202136161e-05 4.752718715461182 0.552739879679441 (ac)ACGLVASNLNLKPGECLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ACGLVASNLNLKPGECLR 18 1 P09382;F8WEI7 P09382 LGALS1 Galectin-1 0 70.54 6.6285e-05 3075700.0 15655.0 13589.0 16881.0 17079.0 21055.0 23056.0 19887.0 23473.0 17677.0 14200.0 False True 18305.082299655885 14938.026113427662 17283.507061549 16122.119000865088 16929.42389458217 21846.90277223169 18003.15939058835 22856.858621699317 17935.49268340156 16774.347592861846 1.0912545002611862 0.8905279940535147 1.0303534588077703 0.9611174987053263 1.0092448484724565 1.302399550938626 1.0732554152060978 1.3626079044305617 1.069221475476866 1.0 14.033969036118204 -6.641690617997916 8.031005153558404 1.1782580314925246 0.988355039983954 0.344652903957795 0.1126129519153105 0.23125668239869637 15.284431061087371 0.034286181687129505 0.03424899658341325 2.2819671171600897e-07 6.641690617997916 -0.1899029915085706 (ac)ACGLVASNLNLKPGECLR ddPTM_PC-9_Lapatinib_30min_R1 1 ACGLVASNLNLKPGECLR 18 1 P09382;F8WEI7 P09382 LGALS1 Galectin-1 0 62.732 0.00020651 11189000.0 26578.0 17547.0 21698.0 18938.0 19749.0 20108.0 19295.0 23446.0 18856.0 14670.0 False True 26198.992846191726 17506.370999584473 19914.07419670215 20330.76369531602 18587.402648027888 19248.02771403741 20294.00068883992 24535.386753831113 16732.238717517335 17205.689953453726 1.5226935343521495 1.0174756750205411 1.157412126486957 1.1816302485001478 1.0803055674205502 1.1187012997507677 1.1794935712395695 1.426004235820028 0.9724828683291858 1.0 14.070598125298746 -14.52287848844675 0.023031777481435665 1.0306156201667779e-06 1.9474244925864919 0.1461977553518149 0.15788918816592518 6657.554388103445 11.54843091179996 688.69658288529 343.1514639764607 3.000001774144094e-15 14.52287848844675 1.9474234619708717 (ac)ACRPRS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 1 ACRPRSPPR 9 2 E7EUV9;F8W8D3;Q14493;Q14493-2 E7EUV9 SLBP Histone RNA hairpin-binding protein 1 ACRPRS(1)PPR 53.968 0.015829 17930000.0 956.74 849.46 0.0 1203.1 0.0 0.0 0.0 0.0 1102.3 0.0 True False 1260.9634185717523 1124.0313329043233 0.0 925.7438827097075 0.0 0.0 0.0 0.0 1160.5653276099492 0.0 0.0 (ac)ACS(ph)PDAVVSPSSAFLR ddPTM_PC-9_AZD4547_30min_R2 2 ACSPDAVVSPSSAFLR 16 0 Q93100-4;Q93100-2;I3L3F2;H3BV13;H3BQ89 Q93100-4 PHKB Phosphorylase b kinase regulatory subunit beta 1 ACS(1)PDAVVSPSSAFLR;ACS(1)PDAVVSPSSAFLR 107.09 2.6385999999999998e-05 14566200.0 1393.5 1169.95 1867.54 1618.8899999999999 3284.7 1709.71 1840.1399999999999 471.16 2100.02 1789.49 True False 1836.6040133993947 1548.1134578807867 1842.7751993710406 1245.6799221011706 2828.6761030491266 1602.8015634239534 2003.9088951764704 398.3530481797058 2211.022769924198 1726.8404997783655 1.0635632032229478 0.8965005500389192 1.0671368893696638 0.7213636246434165 1.6380644902712083 0.9281700096967079 1.1604481684519594 0.2306831744048354 1.2803862141338334 1.0 10.753919118654837 (ac)ACS(ph)PDAVVSPSSAFLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ACSPDAVVSPSSAFLR 16 0 Q93100-4;Q93100-2;I3L3F2;H3BV13;H3BQ89 Q93100-4 PHKB Phosphorylase b kinase regulatory subunit beta 1 ACS(0.999)PDAVVSPSSAFLR;ACS(0.999)PDAVVSPSSAFLR 60.161 0.0030503 6139600.0 815.29 1310.3 1488.65 1095.2 787.3900000000001 0.0 1770.52 2651.1 1509.81 1132.5 True False 953.3024942884991 1440.3779245289777 1524.1450617365638 1033.8394946863068 633.1065818264092 0.0 1602.8035281452464 2581.5114340726395 1531.8881149701028 1337.8132851349333 0.7125826188759578 1.076665884943503 1.1392808538172328 0.7727830977415003 0.4732398675219864 0.0 1.1980771501933365 1.929650021237654 1.1450686967991912 1.0 10.385661061772396 -7.510379758726238 24.65580551433508 1.4351883915462043 0.7159876306765303 0.3984841645733411 0.37444875690761437 497.05881743993694 980516.8951766228 0.17314740185526992 0.11008715940097405 3.087594376533155e-08 7.510379758726238 -0.719200760869674 (ac)ACS(ph)PDAVVSPSSAFLR ddPTM_PC-9_Lapatinib_30min_R1 1 ACSPDAVVSPSSAFLR 16 0 Q93100-4;Q93100-2;I3L3F2;H3BV13;H3BQ89 Q93100-4 PHKB Phosphorylase b kinase regulatory subunit beta 1 ACS(0.39)PDAVVS(0.348)PS(0.131)S(0.131)AFLR 68.786 0.013153999999999999 1110800.0 8916.7 7156.4 8009.1 7995.8 9406.2 8030.1 7023.2 7948.5 7419.8 7987.7 True False 8789.546222877487 7139.829795487907 7350.62271402005 8583.83780520688 8852.945809300722 7686.671342077378 7386.826931218476 8317.81632742586 6584.1039900421665 9368.363302058773 0.9382157736075322 0.7621213615743181 0.7846218679846342 0.9162579981628715 0.9449831869089893 0.820492448279431 0.7884863869012383 0.8878622721215299 0.7028019492578023 1.0 13.193581308826955 -11.79372509955334 2.394451006180773 1.7146969772625582 0.8394810379573714 0.2821518188186013 0.07729873419955187 12604187.360447848 2773146.3774560676 48487707.626646094 0.019059009026804758 1.6079587393627958e-12 11.79372509955334 -0.8752159393051868 (ac)ACSPDAVVSPS(ph)SAFLR ddPTM_PC-9_Lapatinib_30min_R1 1 ACSPDAVVSPSSAFLR 16 0 Q93100-4;Q93100-2;I3L3F2;H3BV13;H3BQ89 Q93100-4 PHKB Phosphorylase b kinase regulatory subunit beta 1 ACS(0.004)PDAVVS(0.105)PS(0.446)S(0.446)AFLR 75.143 0.018678 1179900.0 4090.1 5269.7 2821.4 4070.0 3437.7 3031.1 3947.4 5090.9 3178.3 3006.5 True False 4031.7744239675217 5257.498333419401 2589.4353829189527 4369.321377121989 3235.50124477824 2901.4669188392077 4151.777057223461 5327.441799244175 2820.3263850172525 3526.1695190905675 1.1433864430339 1.490994209142662 0.7343479571528917 1.2391126840234494 0.9175682641635183 0.8228381826598976 1.1774184521605882 1.5108297461031235 0.7998272260446064 1.0 11.783886117934061 -5.242099000745977 24.997001585087414 1.0454855053801144 1.317190287242818 0.19286018324379905 0.23601204946588664 1446.4983452307717 1869559.8729910161 0.05960856366867379 0.1571993888021376 5.726654726347785e-06 5.242099000745977 0.27170478186270364 (ac)ADANKAEVPGAT(ph)GGDSPHLQPAEPPGEPR ddPTM_PC-9_Lapatinib_30min_R1 1 ADANKAEVPGATGGDSPHLQPAEPPGEPR 29 1 A0A0A0MQW0;Q9P2K5-2;A0A087WWC8;A0A0A0MR39;Q9P2K5-4;Q9P2K5 A0A0A0MQW0 MYEF2 Myelin expression factor 2 1 ADANKAEVPGAT(0.986)GGDS(0.014)PHLQPAEPPGEPR 61.033 1.2457e-08 5065000.0 24492.0 17174.0 24203.0 12745.0 15305.0 20221.0 11876.0 13876.0 20249.0 15045.0 True False 24142.73958871727 17134.234658167417 22213.12276628177 13682.309816073655 14404.78999078773 19356.194967453288 12490.88117028572 14520.729616828481 17968.34438857703 17645.508203797628 1.3682087990824385 0.9710252864510768 1.258854236995062 0.7753990226889004 0.8163431636209584 1.0969474352281614 0.707878799863495 0.8229136531020037 1.0182956580819769 1.0 14.107013360958693 -5.7586258155874175 24.99993942861077 0.8815590035933073 1.1765290574297635 0.47975135439497485 0.14628567078430396 63.78491246307702 566748.2373160799 0.038933690534961526 0.06378136682101218 1.7433082459940733e-06 5.7586258155874175 0.29497005383645625 (ac)ADAWEEIRR ddPTM_PC-9_AZD4547_30min_R2 1 ADAWEEIRR 9 1 O94874-3;O94874 O94874-3 UFL1 E3 UFM1-protein ligase 1 0 55.531000000000006 0.011753 1331300.0 8415.0 8848.8 6241.2 7308.5 7645.7 6094.4 6460.7 7050.8 6556.5 7495.3 False True 11090.794957126589 11709.001552284724 6158.43761007236 5623.638240199398 6584.22652938859 5713.316204579101 7035.689783965682 5961.26087126553 6903.06320463996 7232.891828391767 1.533383219363399 1.618854785899407 0.8514488749711729 0.7775089651036318 0.9103172957105584 0.7899075971456159 0.972735380383819 0.8241877540412512 0.9543987893670539 1.0 12.82035686024049 -5.26236242504492 24.999713839108335 0.8755775197867298 1.5761190574980841 0.9314586032159768 0.07494854626134735 15.70076810424805 425253.23373176897 0.018257602159393472 0.04190099220871062 5.465596605599941e-06 5.26236242504492 0.7005415377113543 (ac)ADAWEEIRR ddPTM_PC-9_Lapatinib_30min_R1 1 ADAWEEIRR 9 1 O94874-3;O94874 O94874-3 UFL1 E3 UFM1-protein ligase 1 0 109.86 0.00049638 1173600.0 6486.6 5043.6 4365.5 5087.0 5581.4 5539.7 5501.7 4698.0 5419.3 5342.4 False True 6394.099894503246 5031.921854077859 4006.585441317319 5461.114949734537 5253.113025454597 5302.779944671429 5786.551105975154 4916.286230892205 4808.921366241073 6265.826721699463 1.0204718672413258 0.8030738923327687 0.6394344464461386 0.8715713332483178 0.838375087402642 0.8463017220548306 0.923509596257345 0.7846189256824476 0.767483937847672 1.0 12.613289157913746 (ac)ADEAALALQPGGS(ph)PSAAGADR ddPTM_PC-9_AZD4547_30min_R2 3 ADEAALALQPGGSPSAAGADR 21 0 Q96EB6;Q96EB6-2 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 ADEAALALQPGGS(0.755)PS(0.245)AAGADR;ADEAALALQPGGS(0.682)PS(0.318)AAGADR;ADEAALALQPGGS(0.655)PS(0.345)AAGADR 110.64 8.9848e-09 25413100.0 52715.6 51664.51 54447.1 86960.4 87388.4 75646.7 71430.5 77962.6 60842.4 75338.46 True False 69478.06424740376 68364.05250294157 53725.095878896864 66913.0233047871 75256.02909358473 70916.49989054434 77787.67612078573 65915.27157232186 64058.40505177857 72700.88344664247 0.9556701508090469 0.9403469292517767 0.7389882121353786 0.9203880356405397 1.0351460054652233 0.9754558201839768 1.0699687876265853 0.9066639695059442 0.8811227871638329 1.0 16.14968527514337 -6.004251425493387 24.988187006537327 0.9778497666989175 0.8753949282086708 0.267169906104324 0.07480530000850313 253.07795530476452 1487512.6349650417 0.022217268694542675 0.032078126622618046 9.902584899596853e-07 6.004251425493387 -0.10245483849024672 (ac)ADEAALALQPGGS(ph)PSAAGADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ADEAALALQPGGSPSAAGADR 21 0 Q96EB6;Q96EB6-2 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 ADEAALALQPGGS(0.633)PS(0.367)AAGADR;ADEAALALQPGGS(0.879)PS(0.121)AAGADR;ADEAALALQPGGS(0.956)PS(0.044)AAGADR 125.92 1.3017e-18 18663400.0 773.41 1781.15 2455.5 4117.7 3180.8599999999997 1157.7 2617.97 2434.33 3066.4700000000003 1894.5500000000002 True False 904.3330374562034 1957.9708007897336 2514.048432535606 3886.998618763518 2557.5933169945674 1096.9881739856262 2369.976929138563 2370.4314168858377 3111.311322558714 2238.0169177504517 0.4040778379661205 0.874868632699074 1.1233375461087256 1.7368048417929496 1.1427944519585396 0.4901608049899223 1.0589629195121326 1.059165995612081 1.3902090274125614 1.0 11.128005226723682 -4.848685102621596 2.5792370544984875 1.1219645348720189 0.31274514203851 0.3576385137139082 0.29563221274834206 0.5113970005191205 4.979701860314009 0.08371487379965033 0.8589065694587513 1.4168207131510288e-05 4.848685102621596 -0.8092193928335089 (ac)ADEAALALQPGGS(ph)PSAAGADR ddPTM_PC-9_Lapatinib_30min_R1 2 ADEAALALQPGGSPSAAGADR 21 0 Q96EB6;Q96EB6-2 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 ADEAALALQPGGS(0.74)PS(0.26)AAGADR;ADEAALALQPGGS(0.86)PS(0.14)AAGADR 109.37 2.5657e-08 20269300.0 5996.6 2166.2 4212.3 4129.9 7414.5 4604.4 4058.3 3039.7 4081.5 2738.7 True False 5911.087384358244 2161.184296990932 3865.980953948218 4433.626622942532 6978.393687467864 4407.480545380639 4268.418916585596 3180.9355589704196 3621.798489899607 3212.0806459116357 1.8402674266232786 0.672830023661363 1.2035753083811493 1.38029741830601 2.172546226804742 1.3721574989066725 1.3288641809222557 0.9903037655729915 1.1275552793201078 1.0 11.649292399807539 -7.64255036837808 3.8084099261271374 1.043656619405899 1.4208437248785828 0.18885111153735712 0.3695054333890818 0.4524606504024051 12.285160553576725 0.20299151424011916 0.1091346821910628 2.2774540931613418e-08 7.64255036837808 0.37718710547268386 (ac)ADEAALALQPGGS(ph)PSAAGADREAASSPAGEPLR ddPTM_PC-9_Lapatinib_30min_R1 1 ADEAALALQPGGSPSAAGADREAASSPAGEPLR 33 1 Q96EB6;Q96EB6-2 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 ADEAALALQPGGS(0.599)PS(0.385)AAGADREAAS(0.007)S(0.009)PAGEPLR 59.536 6.8277e-12 3732400.0 0.0 0.0 557.32 501.42 0.0 0.0 0.0 0.0 645.95 0.0 True False 0.0 0.0 511.49930091741373 538.2960994880856 0.0 0.0 0.0 0.0 573.1963088449475 0.0 0.0 (ac)ADEAALALQPGGSPS(ph)AAGADREAASSPAGEPLR ddPTM_PC-9_AZD4547_30min_R2 1 ADEAALALQPGGSPSAAGADREAASSPAGEPLR 33 1 Q96EB6;Q96EB6-2 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 ADEAALALQPGGS(0.441)PS(0.556)AAGADREAAS(0.002)S(0.001)PAGEPLR 61.03 8.856799999999999e-09 5171500.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)ADEAALALQPGGSPS(ph)AAGADREAASSPAGEPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADEAALALQPGGSPSAAGADREAASSPAGEPLR 33 1 Q96EB6;Q96EB6-2 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 ADEAALALQPGGS(0.082)PS(0.87)AAGADREAAS(0.032)S(0.016)PAGEPLR 45.846000000000004 3.6684e-06 4298900.0 0.0 0.0 0.0 0.0 617.54 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 496.537470047982 0.0 0.0 0.0 0.0 0.0 0.0 (ac)ADEAALALQPGGSPS(ph)AAGADREAASSPAGEPLR ddPTM_PC-9_Lapatinib_30min_R1 1 ADEAALALQPGGSPSAAGADREAASSPAGEPLR 33 1 Q96EB6;Q96EB6-2 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 ADEAALALQPGGS(0.176)PS(0.787)AAGADREAAS(0.017)S(0.02)PAGEPLR 41.375 1.0198e-05 3591000.0 0.0 0.0 682.08 737.99 469.73 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 626.0020153049401 792.2642464624706 442.1014049247125 0.0 0.0 0.0 0.0 0.0 0.0 (ac)ADEELEALRR ddPTM_PC-9_Lapatinib_30min_R1 1 ADEELEALRR 10 1 K7ESJ4;O14737;O14737-2;Q3HM38;X6R2P6 K7ESJ4 PDCD5 Programmed cell death protein 5 0 58.23 0.0014581 9330800.0 39941.0 38850.0 30156.0 24335.0 29388.0 28755.0 25679.0 35395.0 28766.0 27844.0 False True 39371.43401571764 38760.04521193687 27676.690085526294 26124.677079180252 27659.45561903104 27525.215681178925 27008.532971688026 37039.58091580026 25526.070160590993 32656.798300202143 1.2056121868956742 1.1868905474330271 0.8475016390493791 0.7999766798638843 0.8469738939123077 0.8428632662684677 0.8270416690395778 1.1342073578465586 0.7816464408402519 1.0 14.995095734354678 -5.2562264473189995 23.31104631256409 0.881846268530709 1.1962514941312048 0.6041687102150948 0.10073885552119219 107.42493383609022 480368.0056160344 0.02579785851914938 0.06382913522331718 5.543365986045176e-06 5.2562264473189995 0.3144052256004958 (ac)ADELS(ph)EK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADELSEK 7 0 C9JKI3;Q03135-2 C9JKI3 CAV1 Caveolin;Caveolin-1 1 ADELS(1)EK 85.676 0.004123399999999999 9907300.0 83384.0 92514.0 60245.0 53398.0 100670.0 42911.0 58521.0 51051.0 52258.0 50332.0 True False 97499.26429092984 101698.178516274 61681.46928043479 50406.28317865179 80944.43616564164 40660.6716195018 52977.46722465037 49710.965343005664 53022.17438757702 59456.79317210723 1.6398338875879594 1.7104551572751712 1.0374166851193585 0.8477800515198106 1.3613992926146383 0.6838692342824976 0.8910246314714382 0.8360855453322095 0.8917765583840996 1.0 15.859554032511436 -5.309084225761182 4.341707913296063 0.931259618114827 1.6829409302668328 0.7572336114908219 0.16626963625409014 0.09131084670902696 3.77351835228526 0.04414817398036684 0.10286111081443207 4.908126801918989e-06 5.309084225761182 0.7516813121520057 (ac)ADELS(ph)EKQVYDAHTK ddPTM_PC-9_AZD4547_30min_R2 2 ADELSEKQVYDAHTK 15 1 C9JKI3;Q03135-2 C9JKI3 CAV1 Caveolin;Caveolin-1 1 ADELS(1)EKQVYDAHTK;ADELS(0.988)EKQVY(0.012)DAHTK 56.29 2.4396999999999997e-05 76740000.0 123621.0 114580.0 160564.0 265162.0 225608.0 115570.0 135893.0 154235.0 113016.0 158933.0 True False 162929.9065234638 151615.7442659778 158434.81644934605 204032.99761206165 194286.2234775499 108343.38963035049 147987.21374037646 130401.5247177112 118989.79503326301 153368.80404544016 1.0623405948656344 0.9885696456305222 1.0330315701125565 1.3303422353845225 1.2667910184654418 0.7064239061175079 0.9649107891363016 0.8502480379196006 0.775840926542067 1.0 17.226645535987743 -6.759354369692707 24.999930278262784 0.8567143633868027 1.1330649236776906 0.5539366275681761 0.1241351894147416 46.40608793981818 556425.3178722246 0.04501501902842393 0.042914633113246003 1.7403861972474983e-07 6.759354369692707 0.2763505602908879 (ac)ADELS(ph)EKQVYDAHTK ddPTM_PC-9_Lapatinib_30min_R1 1 ADELSEKQVYDAHTK 15 1 C9JKI3;Q03135-2 C9JKI3 CAV1 Caveolin;Caveolin-1 1 ADELS(0.887)EKQVY(0.113)DAHTK 57.148999999999994 0.0033033000000000003 7493900.0 52302.0 24480.0 23017.0 12719.0 13547.0 10088.0 5628.4 6334.2 22544.0 6764.2 True False 51556.163888987874 24423.31806404673 21124.631108189395 13654.397689340194 12750.192094426753 9656.559756276576 5919.811012027294 6628.510056133968 20004.857321155632 7933.382957270049 6.4986354707284715 3.0785502471761457 2.6627519712547163 1.7211318000005889 1.6071570177691528 1.2172058008907072 0.7461899978750498 0.8355212513798653 2.521604897797533 1.0 12.953720476561113 -2.2962668344449075 0.7083270812580439 1.2550514776752335 199.9999999999655 0.8997223676984223 0.515772510347041 24.77714317291539 0.4248592669942553 0.19993342268331685 7432.6465124195765 0.00505513974225158 2.2962668344449075 198.74494852229026 up (ac)ADFDDRVSDEEK ddPTM_PC-9_AZD4547_30min_R2 1 ADFDDRVSDEEK 12 1 P52907 P52907 CAPZA1 F-actin-capping protein subunit alpha-1 0 66.595 0.030029000000000004 6190900.0 16282.0 15727.0 17237.0 22299.0 23279.0 18866.0 19972.0 16997.0 17399.0 20397.0 False True 21459.337313361266 20810.445191752748 17008.426117544284 17158.310066115686 20047.11267478935 17686.30603760656 21749.469309109343 14370.504202204032 18318.675619237503 19682.9072383636 1.0902524232566242 1.0572851327161408 0.8641216417660835 0.8717365711439584 1.0185036403421077 0.8985616719838265 1.1049927251965017 0.7301006923507083 0.930689526572218 1.0 14.264655707370954 -5.149336252109422 5.623778746344552 0.9245627906834805 1.081141904883007 0.2723094637856164 0.09607009945257203 0.2802940039483838 11.918421113894624 0.02406847263757627 0.06683345768421416 7.090285906464186e-06 5.149336252109422 0.15657911419952664 (ac)ADFDDRVSDEEK ddPTM_PC-9_Lapatinib_30min_R1 1 ADFDDRVSDEEK 12 1 P52907 P52907 CAPZA1 F-actin-capping protein subunit alpha-1 0 65.278 0.030081999999999998 6837400.0 26864.0 27036.0 23499.0 24139.0 25915.0 27785.0 19008.0 21148.0 26068.0 17747.0 False True 26480.914433745747 26973.39980308689 21567.002928763195 25914.26258534342 24390.730650850328 26596.70031999849 19992.141233141712 22130.61328456968 23131.947331790514 20814.54530360893 1.2722312232856872 1.2958918587767616 1.036150567508376 1.2450073834113624 1.17181184095438 1.2777939624454357 0.9604889725683978 1.0632282839602825 1.1113357027203365 1.0 14.34530442251504 -1.9836002772848869 0.12497349330793868 0.9329497590143613 1.9569709978967091 0.41703496961706676 0.09099124292206423 80.7404745787241 0.7712221444276477 0.5905832066493875 14.233485462225518 0.010384837919651899 1.9836002772848869 1.024021238882348 (ac)ADGDS(ph)GSERGGGGGPCGFQPASR ddPTM_PC-9_AZD4547_30min_R2 1 ADGDSGSERGGGGGPCGFQPASR 23 1 Q96QR8 Q96QR8 PURB Transcriptional activator protein Pur-beta 1 ADGDS(0.5)GS(0.5)ERGGGGGPCGFQPASR 68.413 9.8874e-09 21003000.0 2793.7 1601.8 6736.2 6048.8 2078.0 5754.7 4903.5 5661.8 2073.2 2432.8 True False 3682.038487430131 2119.55052509376 6646.873586645106 4654.342613028413 1789.5055688909436 5394.85769927989 5339.902000661811 4786.898905220853 2182.7851194783148 2347.6284124866906 1.568407703640793 0.9028475349080723 2.8313141684993086 1.9825721090580812 0.7622609947012169 2.2980032404555315 2.2745942127210834 2.0390360245088366 0.9297830558994777 1.0 11.196988358405202 (ac)ADGDS(ph)GSERGGGGGPCGFQPASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADGDSGSERGGGGGPCGFQPASR 23 1 Q96QR8 Q96QR8 PURB Transcriptional activator protein Pur-beta 1 ADGDS(0.5)GS(0.5)ERGGGGGPCGFQPASR 65.528 0.0023941999999999995 0.0 1248.2 1427.2 857.51 2643.3 919.35 1281.7 1435.6 1127.5 2560.1 802.27 True False 1459.4956069262514 1568.8829839637929 877.9562905247842 2495.204470694226 739.209967109195 1214.4853956961024 1299.6095751560636 1097.9043196849989 2597.536619266639 947.7152002341746 1.5400149818907822 1.6554371857453922 0.9263925389271446 2.632863195691782 0.7799916756917487 1.2814877247890617 1.3713081470413664 1.1584749505059257 2.7408409389495954 1.0 9.888309766893322 -3.15787872036493 0.7262972902736833 1.48874730470032 2.315005213506072 0.0005839874470675577 0.6421876536705972 574.9177242870205 34.30171969842215 0.2396002170589467 647.2942500304241 0.0006952184348751168 3.15787872036493 0.8262579088057522 (ac)ADGDS(ph)GSERGGGGGPCGFQPASR ddPTM_PC-9_Lapatinib_30min_R1 1 ADGDSGSERGGGGGPCGFQPASR 23 1 Q96QR8 Q96QR8 PURB Transcriptional activator protein Pur-beta 1 ADGDS(0.5)GS(0.5)ERGGGGGPCGFQPAS(0.001)R 52.42 5.7441e-07 20359000.0 3915.4 2046.7 3854.7 1667.9 2071.8 4981.0 5001.7 4289.2 1100.3 1414.0 True False 3859.5656780035793 2041.9609918988735 3537.7814455722996 1790.5629299512943 1949.9407973155194 4767.974241278116 5260.663552493945 4488.491890494431 976.37262732734 1658.4080159634332 2.3272714801498404 1.2312778111559113 2.133239475158389 1.0796878166987678 1.1757907454292686 2.875030870197655 3.1721165731569516 2.706506388831516 0.5887408996634206 1.0 10.695583279547392 -6.748751510838492 24.997211039914887 2.244113056922844 1.571444904877514 0.05511991980929554 0.8462918634581541 500.0214747149884 985123.8632381187 0.2823051417453242 0.28051037361956405 1.7833988783521854e-07 6.748751510838492 -0.6726681520453297 (ac)ADGDSGS(ph)ERGGGGGPCGFQPASR ddPTM_PC-9_AZD4547_30min_R2 1 ADGDSGSERGGGGGPCGFQPASR 23 1 Q96QR8 Q96QR8 PURB Transcriptional activator protein Pur-beta 1 ADGDS(0.237)GS(0.762)ERGGGGGPCGFQPASR 58.461000000000006 0.0037028 0.0 984.66 0.0 1271.2 1689.6 1626.2 902.52 1067.9 0.0 1046.0 1014.3 True False 1297.7613977996753 0.0 1254.3430574126746 1300.0888240597806 1400.4302002552704 846.0852817269506 1162.9410312035784 0.0 1101.2894245486773 978.7896657288927 1.325883837191158 0.0 1.2815246230440946 1.3282616986884719 1.4307774686325352 0.8644199171196615 1.188141918455535 0.0 1.1251543238644235 1.0 9.934855058988937 (ac)ADGDSGS(ph)ERGGGGGPCGFQPASR ddPTM_PC-9_Lapatinib_30min_R1 1 ADGDSGSERGGGGGPCGFQPASR 23 1 Q96QR8 Q96QR8 PURB Transcriptional activator protein Pur-beta 1 ADGDS(0.255)GS(0.745)ERGGGGGPCGFQPASR 78.249 0.0015457000000000001 0.0 1075.6 0.0 0.0 842.25 982.16 936.0 0.0 831.48 0.0 0.0 True False 1060.2617467591178 0.0 0.0 904.1918746636354 924.3912798008546 895.9694619225692 0.0 870.1135962669755 0.0 0.0 0.0 (ac)ADGGS(ph)PFLGRR ddPTM_PC-9_AZD4547_30min_R2 1 ADGGSPFLGRR 11 1 O60504-2;E5RIA0;E5RJP2 O60504-2 SORBS3 Vinexin 1 ADGGS(1)PFLGRR 56.551 0.004123300000000001 10619000.0 2506.6 1790.3 8701.3 11910.0 11264.0 7571.5 7121.9 9748.5 6787.8 7877.7 True False 3303.6466594811045 2368.9794637753535 8585.915076671574 9164.333507665717 9700.188030792866 7098.052908074736 7755.735303051558 8242.093323244464 7146.589250431654 7601.9041207852615 0.4345814689306874 0.3116297477756984 1.1294426949158451 1.2055313197924231 1.276020833289707 0.9337203936402082 1.0202358750942002 1.0842143221339489 0.9401051548244765 1.0 12.892145113947741 -5.262112780114631 24.99706107318411 1.0816976750260938 0.3731055549340784 0.8718547516506483 0.1073957961031387 18.49996932118983 686763.0117323765 0.029715637177023656 0.06843957390405615 5.468739290530472e-06 5.262112780114631 -0.7085921200920154 (ac)ADGGS(ph)PFLGRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ADGGSPFLGRR 11 1 O60504-2;E5RIA0;E5RJP2 O60504-2 SORBS3 Vinexin 1 ADGGS(1)PFLGRR;ADGGS(1)PFLGRR 57.885 0.006291399999999999 19886600.0 28980.0 34281.0 41898.0 36260.0 48262.0 32015.0 35677.0 35462.0 27283.0 27034.0 True False 33885.74161890946 37684.191124763725 42897.007219049854 34228.469756506114 38805.407551665834 30336.077040813532 32297.416280888065 34531.16007509482 27681.96226063501 31935.05019897375 1.0610830860694371 1.1800260494337576 1.3432578609326367 1.0718151229837762 1.2151353234106663 0.9499304636066738 1.0113469707940512 1.0812934333888882 0.8668206903750095 1.0 14.962853097847052 -6.761069737501693 24.99999563316411 0.9888009275962015 1.1782806455290868 0.5378625094567155 0.0890099433074661 8.122959765454642 549399.93481668 0.030124922978448723 0.028368579640523875 1.7335256118730408e-07 6.761069737501693 0.18947971793288532 (ac)ADGGS(ph)PFLGRR ddPTM_PC-9_Lapatinib_30min_R1 3 ADGGSPFLGRR 11 1 O60504-2;E5RIA0;E5RJP2 O60504-2 SORBS3 Vinexin 1 ADGGS(1)PFLGRR;ADGGS(1)PFLGRR;ADGGS(1)PFLGRR 65.241 0.0079829 40311000.0 24514.300000000003 25676.9 34901.7 19273.100000000002 26360.0 25922.8 19925.4 22133.3 29715.1 18574.7 True False 24164.72158662797 25617.446715634036 32032.216950458056 20690.508067176852 24809.55662575399 24814.142272998266 20957.039716269024 23161.693919584162 26368.272524124903 21785.312145768017 1.109220810100817 1.1759045059453253 1.4703584110306442 0.9497457703949475 1.1388203418776104 1.1390308344890356 0.9619802358599717 1.0631793460018666 1.2103692775982173 1.0 14.411068164270297 -5.7858720805222505 24.999982393054676 1.0705162089082736 1.2442359422659617 0.3492088019257189 0.1159052888411307 261.0938421922032 267155.01389021386 0.032670583036817843 0.04848368754403049 1.6372987093496413e-06 5.7858720805222505 0.1737197333576881 (ac)ADHNPDSDS(ph)TPR ddPTM_PC-9_AZD4547_30min_R2 1 ADHNPDSDSTPR 12 0 Q96BT3;H3BMP6;H3BQS6;H3BN05;H3BTS2;H3BQJ0;I3L4F8;H3BUW2;H3BTR4;Q96BT3-3;Q96BT3-2;H3BQ71 Q96BT3 CENPT Centromere protein T 1 ADHNPDS(0.099)DS(0.45)T(0.45)PR 49.356 0.0083035 1927200.0 0.0 0.0 445.12 0.0 0.0 0.0 0.0 523.24 0.0 0.0 True False 0.0 0.0 439.21741796375846 0.0 0.0 0.0 0.0 442.38528085904795 0.0 0.0 0.0 (ac)ADHNPDSDS(ph)TPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADHNPDSDSTPR 12 0 Q96BT3;H3BMP6;H3BQS6;H3BN05;H3BTS2;H3BQJ0;I3L4F8;H3BUW2;H3BTR4;Q96BT3-3;Q96BT3-2;H3BQ71 Q96BT3 CENPT Centromere protein T 1 ADHNPDS(0.011)DS(0.494)T(0.494)PR 54.199 0.0026596 1295700.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)ADHNPDSDST(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 ADHNPDSDSTPR 12 0 Q96BT3;H3BMP6;H3BQS6;H3BN05;H3BTS2;H3BQJ0;I3L4F8;H3BUW2;H3BTR4;Q96BT3-3;Q96BT3-2;H3BQ71 Q96BT3 CENPT Centromere protein T 1 ADHNPDS(0.007)DS(0.057)T(0.936)PR 68.46300000000001 0.0019158 2007200.0 537.62 0.0 494.22 716.77 448.02 0.0 0.0 0.0 0.0 0.0 True False 708.5719768093165 0.0 487.6663198823885 551.5297504861089 385.82015638812356 0.0 0.0 0.0 0.0 0.0 0.0 (ac)ADHNPDSDST(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADHNPDSDSTPR 12 0 Q96BT3;H3BMP6;H3BQS6;H3BN05;H3BTS2;H3BQJ0;I3L4F8;H3BUW2;H3BTR4;Q96BT3-3;Q96BT3-2;H3BQ71 Q96BT3 CENPT Centromere protein T 1 ADHNPDS(0.005)DS(0.047)T(0.948)PR 74.53699999999999 0.00053446 1934800.0 0.0 0.0 0.0 0.0 0.0 590.92 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 559.9311149447925 0.0 0.0 0.0 0.0 0.0 (ac)ADHNPDSDST(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 ADHNPDSDSTPR 12 0 Q96BT3;H3BMP6;H3BQS6;H3BN05;H3BTS2;H3BQJ0;I3L4F8;H3BUW2;H3BTR4;Q96BT3-3;Q96BT3-2;H3BQ71 Q96BT3 CENPT Centromere protein T 1 ADHNPDS(0.001)DS(0.056)T(0.944)PR;ADHNPDS(0.001)DS(0.049)T(0.95)PR 97.95700000000001 0.0010027999999999999 2870500.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)ADHS(ph)FSDGVPSDSVEAAK ddPTM_PC-9_AZD4547_30min_R2 3 ADHSFSDGVPSDSVEAAK 18 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;E9PKT8;C9JZI7;E9PNW0;E9PJJ2;E9PKI2;E9PP22;C9J1B1 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 ADHS(0.959)FS(0.041)DGVPSDSVEAAK;ADHS(0.984)FS(0.015)DGVPSDSVEAAK;ADHS(0.983)FS(0.014)DGVPSDS(0.003)VEAAK 111.63 1.5538e-07 69639300.0 52157.7 43353.2 77897.4 104171.0 84322.6 89074.7 61477.9 96637.0 69298.2 89096.6 True False 68742.76365244458 57366.274081967065 76864.42957874297 80155.98537590647 72615.86250402474 83504.84492780629 66949.31400152684 81703.97214734308 72961.16137692078 85977.3551528945 0.7995449910060453 0.6672253871958724 0.8940078401115514 0.9322918253691822 0.8445928858231465 0.9712423088534031 0.7786854327220246 0.950296412375654 0.848609046500362 1.0 16.39166911017199 -5.277836172051934 24.050788461030884 0.8977245205203628 0.7333852026313106 0.4869805157088929 0.0692802291771924 331.129995988448 485701.0758197791 0.016572449327024032 0.03467845159519698 5.27428784696148e-06 5.277836172051934 -0.1643393178890522 (ac)ADHS(ph)FSDGVPSDSVEAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ADHSFSDGVPSDSVEAAK 18 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;E9PKT8;C9JZI7;E9PNW0;E9PJJ2;E9PKI2;E9PP22;C9J1B1 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 ADHS(0.988)FS(0.012)DGVPSDSVEAAK;ADHS(0.855)FS(0.144)DGVPSDSVEAAK;ADHS(0.996)FS(0.004)DGVPSDSVEAAK 125.61 1.0868999999999997e-137 71628000.0 90417.0 94420.0 116833.0 119182.0 133031.0 121390.0 133514.0 130483.0 111721.0 88813.0 True False 105722.81228284811 103793.39359995906 119618.74181161997 112504.61893325727 106964.53052102397 115024.09470511801 120866.58736234826 127057.95950816615 113354.70826963348 104914.09385667894 1.007708386894843 0.989317924641747 1.140158937797516 1.072349908363576 1.0195439581944643 1.096364563394601 1.1520529122375274 1.2110666435506512 1.0804526265506815 1.0 16.678848972860372 -6.968900229766766 5.586959271558603 1.1281298089766285 1.0496888832177003 0.17195576948362623 0.06416668785080598 0.2642857772899225 22.87297363223603 0.023330337521889496 0.020123506788307 1.0742361676825468e-07 6.968900229766766 -0.07844092575892825 (ac)ADHS(ph)FSDGVPSDSVEAAK ddPTM_PC-9_Lapatinib_30min_R1 4 ADHSFSDGVPSDSVEAAK 18 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;E9PKT8;C9JZI7;E9PNW0;E9PJJ2;E9PKI2;E9PP22;C9J1B1 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 ADHS(0.977)FS(0.023)DGVPSDSVEAAK;ADHS(0.999)FSDGVPSDSVEAAK;ADHS(0.998)FS(0.001)DGVPSDSVEAAK;ADHS(0.99)FS(0.006)DGVPSDS(0.004)VEAAK 116.54 6.4914e-06 72579600.0 79730.9 65035.4 78457.3 77038.6 79577.2 83843.6 60521.6 64307.899999999994 87109.0 56005.1 True False 78593.92274514376 64884.814527063085 72006.84364793602 82704.27563723578 74896.6255507948 80257.80467697764 63655.11231353684 67295.87980153105 77297.86712156441 65685.50691289503 1.1965184778031244 0.9878102122756892 1.0962364002674694 1.2590947306977351 1.1402306090156928 1.2218495136744063 0.9690891538364669 1.0245164110672316 1.1767872511674218 1.0 16.003287463773553 -10.411467162927979 5.304492002931592 0.9999998633898585 1.1151536855948447 0.12393786068521306 0.0944854427695224 1.691473238180109e-07 3.559000529672366e-08 0.09454670187137797 0.02293091404757318 3.8773306395820445e-11 10.411467162927979 0.11515382220498627 (ac)ADHSFS(ph)DGVPSDSVEAAK ddPTM_PC-9_AZD4547_30min_R2 1 ADHSFSDGVPSDSVEAAK 18 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;E9PKT8;C9JZI7;E9PNW0;E9PJJ2;E9PKI2;E9PP22;C9J1B1 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 ADHS(0.104)FS(0.887)DGVPS(0.008)DS(0.001)VEAAK 51.606 0.0023462 0.0 0.0 3445.6 3793.8 4533.7 3512.0 4869.6 1581.4 2547.3 3052.6 5063.3 True False 0.0 4559.322817619592 3743.4917331751158 3488.525509966755 3024.41942153272 4565.103142199136 1722.1415364222673 2153.673316130749 3213.9542039935845 4886.035408148573 0.0 0.9331333968673019 0.7661614009042983 0.7139787616251915 0.6189925305266545 0.9343164264806166 0.3524619435934102 0.4407813567087561 0.6577836498347078 1.0 12.254448603235586 -11.932731259249785 1.9043960754895555 3.30480781276913 0.6180191764384207 0.16382559539524189 0.26757410283229327 13585778.852400465 1210610.9232787834 134672051.36043403 0.06524397450771928 1.167531860476496e-12 11.932731259249785 -2.6867886363307094 (ac)ADHSFS(ph)DGVPSDSVEAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ADHSFSDGVPSDSVEAAK 18 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;E9PKT8;C9JZI7;E9PNW0;E9PJJ2;E9PKI2;E9PP22;C9J1B1 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 ADHS(0.035)FS(0.953)DGVPS(0.005)DS(0.008)VEAAK;ADHS(0.018)FS(0.982)DGVPSDSVEAAK 107.63 1.0939999999999999e-96 26000000.0 76559.0 70017.1 82476.0 87305.0 97260.0 78060.9 87699.0 110385.0 81864.0 67735.2 True False 89518.92659082417 76967.93496110672 84442.54063197179 82413.58389662896 78202.60118675198 73967.24898563926 79391.51583422373 107487.51071257511 83061.10612852781 80015.05556845179 1.1187760347706306 0.9619181592051973 1.0553331498936764 1.029975962787719 0.9773485831032227 0.9244166420950779 0.9922072198813305 1.343341074363449 1.03806846772068 1.0 16.287983861428827 (ac)ADKEAAFDDAVEER ddPTM_PC-9_AZD4547_30min_R2 2 ADKEAAFDDAVEER 14 1 Q09028-3;Q09028;E9PNS2;E9PIC4;E9PNS6 Q09028-3 RBBP4 Histone-binding protein RBBP4 0 ; 69.815 0.00017774 7518000.0 26532.0 22939.0 28889.0 47507.0 39366.0 35017.0 29580.0 33413.0 29373.0 35809.0 False True 34968.62410011679 30353.58315340603 28505.91298426271 36554.99512583333 33900.710406622195 32827.38145440839 32212.56269594703 28249.788604356265 30925.596813832024 34555.337809411314 1.0119601287935582 0.8784050476027783 0.8249351559370081 1.0578682612640355 0.981055679258594 0.9499945170690153 0.9322022222330519 0.817523149684339 0.8949586018924488 1.0 15.076620962416454 -9.693909166901205 6.373902098065325 0.9999999948893518 0.9261380102073321 0.08041169738112419 0.07323247234833559 100153555.10472062 526248722.64349115 0.0745320553783353 0.019244097863081344 2.0234423392902596e-10 9.693909166901205 -0.07386198468201965 (ac)ADKTPGGS(ph)QK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADKTPGGSQK 10 1 O15042-2;O15042;E7ET15;C9J5L1;E7EW00 O15042-2 U2SURP U2 snRNP-associated SURP motif-containing protein 1 ADKT(0.35)PGGS(0.65)QK 63.32 0.0024369 16972000.0 136050.0 157810.0 147850.0 131360.0 249000.0 210440.0 154280.0 157400.0 181180.0 166760.0 True False 159080.57789001477 173476.3338700439 151375.30472424737 124000.32507486589 200210.23746145563 199404.15594155245 139665.48150952737 153268.4167790855 183829.414741115 196992.26792856646 0.8075473193074802 0.8806250909957037 0.7684327223398394 0.6294679805393734 1.01633551187936 1.0122435669092382 0.7089896622753387 0.7780428053890107 0.9331808637675841 1.0 17.58777947853455 -6.269428365795804 24.99148690870607 0.8922826543579124 0.7790912233147905 0.25878114366020777 0.11105048379028323 1117.6901340314007 3496401.78104327 0.03705636380356694 0.04278112750793505 5.377391225692287e-07 6.269428365795804 -0.1131914310431219 (ac)ADLEEQLS(ph)DEEKVR ddPTM_PC-9_AZD4547_30min_R2 2 ADLEEQLSDEEKVR 14 1 P47755;C9JUG7;F8W9N7;P47755-2 P47755 CAPZA2 F-actin-capping protein subunit alpha-2 1 ADLEEQLS(1)DEEKVR;ADLEEQLS(1)DEEKVR 109.95 8.455600000000001e-05 19664900.0 72326.0 56565.0 62692.0 83504.0 86493.0 69643.0 62385.0 69131.0 67894.0 70779.0 True False 95324.16352574408 74848.53006113652 61860.66311777489 64253.442923939314 74484.93992785583 65288.21220062717 67937.14414424117 58448.39242234322 71482.73823165185 68301.04875345106 1.395647142547392 1.0958620903658471 0.9057059041812919 0.9407387455480728 1.0905387440934764 0.9558888683583843 0.9946720494655436 0.8557466318464105 1.046583318064205 1.0 16.059620110623918 -4.815284112229667 2.864815426933849 0.9721635971908423 1.4534329375910269 0.7989611476991125 0.06394037955794847 0.15499391240682234 1.8834058514996281 0.016232185573764275 0.17007605408185852 1.5300861631747067e-05 4.815284112229667 0.48126934040018454 (ac)ADLEEQLS(ph)DEEKVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ADLEEQLSDEEKVR 14 1 P47755;C9JUG7;F8W9N7;P47755-2 P47755 CAPZA2 F-actin-capping protein subunit alpha-2 1 ADLEEQLS(1)DEEKVR;ADLEEQLS(1)DEEKVR 69.26100000000001 0.012161 11317000.0 39028.0 33160.0 35808.0 45826.0 45817.0 44157.0 46715.0 49263.0 40997.0 32065.0 True False 45634.669561863324 36451.9056531946 36661.798522596204 43258.51778989658 36839.48775008649 41841.32918604415 42289.81701268846 47969.89844846302 41596.503566296 37878.130673599684 1.2047761795613054 0.9623470061736933 0.967888274068096 1.1420446843763312 0.9725793510650432 1.1046302560861785 1.1164705401410855 1.2664272918277115 1.0981667475815524 1.0 15.209077513563955 -6.989269470802204 23.659700432472423 1.1379087194281967 1.0449197726113106 0.10051800191184534 0.0951564121046757 197.16172369452084 434717.19546101056 0.03264515476008007 0.028757124130578272 1.0250157277005845e-07 6.989269470802204 -0.09298894681688608 (ac)ADLEEQLS(ph)DEEKVR ddPTM_PC-9_Lapatinib_30min_R1 2 ADLEEQLSDEEKVR 14 1 P47755;C9JUG7;F8W9N7;P47755-2 P47755 CAPZA2 F-actin-capping protein subunit alpha-2 1 ADLEEQLS(1)DEEKVR;ADLEEQLS(1)DEEKVR 101.45 2.0495e-05 9587800.0 46066.0 44782.0 35869.0 38834.0 45525.0 39882.0 41508.0 38828.0 41150.0 31390.0 True False 45409.09039253024 44678.310030397886 32919.98927834403 41689.98190642636 42847.30900559369 38176.33982948281 43657.08113979616 40632.090628582926 36515.25367128966 36815.71967545413 1.2334158015334278 1.2135661186106304 0.8941829622929395 1.1323962229705375 1.1638319007019429 1.0369575867597622 1.1858271826451168 1.1036614518681611 0.9918386491745048 1.0 15.16803428320747 -1.5228787452803376 0.08282310998550006 0.9333350834954555 1.5445546033242896 0.1888059689273175 0.09490707698649707 387.0372523851238 2.33711490764478 2.5010157538076228 26.997652555622857 0.029999999999999995 1.5228787452803376 0.6112195198288342 (ac)ADQLTEEQIAEFK ddPTM_PC-9_AZD4547_30min_R2 2 ADQLTEEQIAEFK 13 0 P0DP25;P0DP24;P0DP23;F8WBR5;M0QZ52;G3V479 P0DP25 CALM2;CALM3;CALM1 0 ; 127.76 2.14e-14 6252500.0 48993.0 50555.0 60930.0 74611.0 68197.0 67978.0 56905.0 63589.0 56154.0 60200.0 False True 64571.754882293906 66895.91509309206 60122.02838904526 57410.586678459054 58729.02371590737 63727.32491383536 61969.43476040787 53762.7811798525 59122.1857993369 58092.41632345392 1.1115350155649155 1.1515429952271388 1.0349376423643772 0.9882630179953525 1.010958528371567 1.0969990395821498 1.066738804861671 0.9254698733911435 1.0177264011562077 1.0 15.826062218796192 -5.336210336086762 5.057044781851804 1.0172804466664649 1.1313301364427661 0.5197311697610355 0.043983333981761796 0.16893386364068477 7.876448988987489 0.01248129250686951 0.027279892733707546 4.610942048327486e-06 5.336210336086762 0.11404968977630126 (ac)ADQLTEEQIAEFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ADQLTEEQIAEFK 13 0 P0DP25;P0DP24;P0DP23;F8WBR5;M0QZ52;G3V479 P0DP25 CALM2;CALM3;CALM1 0 ; 144.55 2.1072e-14 6576900.0 43932.0 46874.0 47343.0 55258.0 59594.0 50759.0 54494.0 49170.0 41455.0 45297.0 False True 51368.81990344826 51527.34094052604 48471.83666932734 52162.073408853146 47916.98349910851 48097.10868388736 49331.93381760556 47879.339599921426 42061.20094984513 53508.98752914531 0.9600035858549679 0.9629660982178011 0.905863461589993 0.9748282637648763 0.8954941162549385 0.8988603766365377 0.9219373435301015 0.8947906101539013 0.7860586210295084 1.0 15.707493610778013 -6.2824264488436095 22.53348172905319 0.8953505561055662 0.9485581209332132 0.19008939132275993 0.05144636761037035 371.41781502925534 398783.326325347 0.01550215915024915 0.01760713503102579 5.21883481791467e-07 6.2824264488436095 0.05320756482764699 (ac)ADQLTEEQIAEFK ddPTM_PC-9_Lapatinib_30min_R1 3 ADQLTEEQIAEFK 13 0 P0DP25;P0DP24;P0DP23;F8WBR5;M0QZ52;G3V479 P0DP25 CALM2;CALM3;CALM1 0 ;; 180.19 9.9408e-34 29580800.0 141184.0 140921.0 170059.0 140076.0 152947.0 139294.0 148189.0 130605.0 142333.0 138067.0 False True 139170.6902700255 140594.70608266062 156077.40546672372 150377.65631983813 143950.95816537167 133336.72033017327 155861.50132565422 136673.38509699347 126301.9587070639 161931.696987287 0.8594406954245132 0.8682346242175087 0.9638471551309508 0.9286486779153809 0.8889609683808417 0.8234133453232527 0.9625138513671642 0.8440187291295014 0.7799705743649414 1.0 17.30502588509585 -6.518605325784835 24.863479789853034 0.8749253596953537 0.906887808533571 0.020946005572743065 0.06588150576358912 619.2848924978678 3603131.608199254 0.021386291899617212 0.021908520023745656 3.0296654494257406e-07 6.518605325784835 0.031962448838217306 (ac)AEAPAS(ph)PAPLSPLEVELDPEFEPQSRPR ddPTM_PC-9_AZD4547_30min_R2 1 AEAPASPAPLSPLEVELDPEFEPQSRPR 28 1 O43524 O43524 FOXO3 Forkhead box protein O3 1 AEAPAS(0.535)PAPLS(0.465)PLEVELDPEFEPQSRPR 45.678999999999995 0.00019350000000000001 1773600.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)AEAPAS(ph)PAPLSPLEVELDPEFEPQSRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEAPASPAPLSPLEVELDPEFEPQSRPR 28 1 O43524 O43524 FOXO3 Forkhead box protein O3 1 AEAPAS(0.84)PAPLS(0.16)PLEVELDPEFEPQSRPR 69.27 4.3305e-06 1780400.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)AEAPAS(ph)PAPLSPLEVELDPEFEPQSRPR ddPTM_PC-9_Lapatinib_30min_R1 1 AEAPASPAPLSPLEVELDPEFEPQSRPR 28 1 O43524 O43524 FOXO3 Forkhead box protein O3 1 AEAPAS(0.531)PAPLS(0.469)PLEVELDPEFEPQSRPR 66.3 1.2972999999999998e-07 2099200.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)AEAPASPAPLS(ph)PLEVELDPEFEPQSRPR ddPTM_PC-9_AZD4547_30min_R2 1 AEAPASPAPLSPLEVELDPEFEPQSRPR 28 1 O43524 O43524 FOXO3 Forkhead box protein O3 1 AEAPAS(0.196)PAPLS(0.804)PLEVELDPEFEPQSRPR 46.403 0.00030516 1991600.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)AEAS(ph)PHPGR ddPTM_PC-9_AZD4547_30min_R2 2 AEASPHPGR 9 0 U3KQF4;K7EIY6;Q9BV68 U3KQF4 RNF126 E3 ubiquitin-protein ligase RNF126 1 AEAS(1)PHPGR;AEAS(1)PHPGR 83.86200000000001 0.0011223 13977000.0 0.0 0.0 0.0 1833.1100000000001 597.41 1171.6 487.15 606.51 0.0 476.12 True False 0.0 0.0 0.0 1410.5148107671794 514.469933547227 1098.3396667899838 530.5054062654021 512.7878157132893 0.0 459.45118371964924 0.0 0.0 0.0 3.069999296438544 1.1197488477059827 2.390547038965026 1.1546502110855572 1.116087701770261 0.0 1.0 8.843767774364448 -5.619463804219471 23.57249816268891 1.438663690321012 0.00021854430381308107 0.4043646152210467 0.7820487909107513 8.945387633459761 2172.3630681182276 0.2131842317883508 0.3692458612392188 2.401796434541267e-06 5.619463804219471 -1.4384451460171988 (ac)AEAS(ph)PHPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AEASPHPGR 9 0 U3KQF4;K7EIY6;Q9BV68 U3KQF4 RNF126 E3 ubiquitin-protein ligase RNF126 1 AEAS(1)PHPGR;AEAS(1)PHPGR 90.149 0.0011223 12321900.0 499.68 0.0 1113.2 0.0 384.27 0.0 391.33 0.0 579.05 0.0 True False 584.2659548701411 0.0 1139.7429098345096 0.0 308.97505200527615 0.0 354.26038941614837 0.0 587.517510795026 0.0 0.0 (ac)AEAS(ph)PHPGR ddPTM_PC-9_Lapatinib_30min_R1 2 AEASPHPGR 9 0 U3KQF4;K7EIY6;Q9BV68 U3KQF4 RNF126 E3 ubiquitin-protein ligase RNF126 1 AEAS(1)PHPGR;AEAS(1)PHPGR 72.2 0.0033804000000000004 12945800.0 0.0 0.0 413.65 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 379.64129373517585 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)AEASSLGRQS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 AEASSLGRQSPR 12 1 Q8N344 Q8N344 MIER2 Mesoderm induction early response protein 2 1 AEAS(0.002)S(0.027)LGRQS(0.971)PR;AEAS(0.004)S(0.012)LGRQS(0.985)PR 45.79 0.0028623 21922000.0 6941.799999999999 6044.6 8106.5 8203.0 6759.5 3740.5 5319.3 7547.1 3685.4 2672.1 True False 9149.148001590174 7998.398741404514 7999.002513306997 6311.925085086641 5821.060102463102 3506.6059436906235 5792.707395150477 6380.869110104969 3880.2027201067835 2578.5505923239393 3.548174710562662 3.1018971530808295 3.102131304741177 2.4478577631466862 2.2574930737414096 1.359913570875593 2.246497475129915 2.4745952742211506 1.5047999180848803 1.0 11.33234463680337 -1.522878745280822 0.17359727480418877 1.0710505175482983 11.575631325503405 0.783247741374995 0.3638374297423801 29.516530717182587 0.3242765464291774 0.9706579344128798 80.96115317115154 0.029999999999966543 1.522878745280822 10.504580807955106 up (ac)AEASSLGRQS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEASSLGRQSPR 12 1 Q8N344 Q8N344 MIER2 Mesoderm induction early response protein 2 1 AEASSLGRQS(0.999)PR 56.956 0.00854 8019300.0 9494.7 9583.0 2606.0 3990.5 2685.4 3753.9 5077.0 2293.7 3931.9 3412.2 True False 11101.965181126972 10534.33690815935 2668.136923310036 3766.925222375558 2159.215147305198 3557.0388756367306 4596.069805703076 2233.492805376037 3989.3965990760116 4030.8048490396595 2.754280000375612 2.613457436588417 0.6619365172059174 0.9345342589019235 0.5356784136596521 0.8824636788070244 1.1402362500377787 0.5541059140851652 0.9897270516647529 1.0 11.976852221624823 -5.25694176343476 24.568021047016778 0.826538003469342 2.683869065203743 0.9371605698447809 0.19124459061522114 58.6494626243543 320366.072568703 0.04723079112396571 0.1163102645263413 5.534243154785131e-06 5.25694176343476 1.857331061734401 (ac)AEEQPQVELFVK ddPTM_PC-9_Lapatinib_30min_R1 2 AEEQPQVELFVK 12 0 O00299 O00299 CLIC1 Chloride intracellular channel protein 1 0 ; 101.32 0.000727 5083300.0 42262.0 37832.0 40389.0 36150.0 39142.0 38015.0 38108.0 35399.0 37903.0 33124.0 False True 41659.33613009841 37744.402328391145 37068.372326048615 38808.59159286485 36839.74451613285 36389.187067293205 40081.045776123974 37043.76677040299 33633.96500371551 38849.43926504438 1.072327861565361 0.9715559102638706 0.9541546294440776 0.9989485646909637 0.9482696587922237 0.9366721310707607 1.031702040862859 0.9535212726669627 0.8657516206154974 1.0 15.245606155135386 -4.761716880460582 4.47626099369212 0.9620178614158412 1.0817310284004813 0.3804183508582477 0.04230337527088055 0.22420359569454226 9.82493450392437 0.010538722817808915 0.08698296474496243 1.7309444059667912e-05 4.761716880460582 0.11971316698464007 (ac)AENHCELLS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 2 AENHCELLSPAR 12 0 H3BSS5;Q9NXV2 H3BSS5 KCTD5 BTB/POZ domain-containing protein KCTD5 1 AENHCELLS(1)PAR;AENHCELLS(1)PAR 81.789 0.00020923 25589000.0 10962.7 11440.099999999999 19795.4 22415.4 24205.2 18207.6 12248.4 36696.9 15191.6 20553.6 True False 14448.610561674595 15137.888601651348 19532.900061915418 17247.875844477752 20844.725792165103 17069.075893688376 13338.483871705135 31026.23731587113 15994.596961733916 19834.024720028956 0.7284759783063083 0.7632282814674867 0.9848177733786198 0.8696104844046283 1.050957941537479 0.8605956750901668 0.6725051551557036 1.5642935689466981 0.8064221552362049 1.0 14.27568983848107 -3.4154263952752055 0.32862444728417817 1.050203903020838 1.0315498517498197e-18 0.14076679241303414 0.22387821638531025 32.97185486398286 1.4144350830569163 0.21240918841084327 16.432220659776853 0.0003842143707513721 3.4154263952752055 -1.050203903020838 (ac)AENHCELLS(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AENHCELLSPAR 12 0 H3BSS5;Q9NXV2 H3BSS5 KCTD5 BTB/POZ domain-containing protein KCTD5 1 AENHCELLS(1)PAR;AENHCELLS(1)PAR 55.213 0.0050642 27468000.0 3340.8 6496.4 12860.1 8223.6 7686.9 6376.4 6440.8 9160.9 7991.599999999999 6275.4 True False 3906.3314561922934 7141.319658788101 13166.733556200848 7762.858353270924 6180.707125873357 6042.01035898933 5830.680796646127 8920.436081775875 8108.4620313781725 7413.080343960935 0.5269511829012599 0.9633403831385392 1.7761487728818595 1.0471838956385973 0.833756932218935 0.815047197473241 0.786539539045478 1.203337299459179 1.093804687815603 1.0 12.855857432257396 -4.794751740116507 4.845328691042278 1.066990347769414 0.5048340473604714 0.2639306610441169 0.26954966163930294 0.2430504033503407 12.71550831551519 0.07292354247014368 0.42247850681021704 1.604162131092197e-05 4.794751740116507 -0.5621563004089426 (ac)AENHCELLS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 2 AENHCELLSPAR 12 0 H3BSS5;Q9NXV2 H3BSS5 KCTD5 BTB/POZ domain-containing protein KCTD5 1 AENHCELLS(1)PAR;AENHCELLS(1)PAR 79.744 0.0013192 36714000.0 7001.8 7163.9 7822.5 5000.2 1089.5 3551.2 1911.6 5037.8 6874.2 1976.9 True False 6901.953048027138 7147.312429698706 7179.36424572322 5367.931388178222 1025.4177520394146 3399.323454251523 2010.573294469364 5271.874579393095 6099.955207464872 2318.604530946329 2.9767702753561576 3.0825922809620145 3.096416033825739 2.315156084848727 0.4422564255150897 1.4661074835664636 0.8671480054637679 2.2737273687813424 2.6308734956949302 1.0 11.179041054669067 -5.997653676477636 5.1472208458427895 1.4700973776221307 3.0198810650784904 0.5884895794530782 0.6049480532162973 0.13443642722298682 10.892255827867778 0.187909053614601 0.2680294615409011 1.0054172299785993e-06 5.997653676477636 1.5497836874563597 (ac)AENPSLENHR ddPTM_PC-9_Lapatinib_30min_R1 1 AENPSLENHR 10 0 O00505 O00505 KPNA3 Importin subunit alpha-4 0 104.2 0.041763999999999996 0.0 10469.0 7731.1 6856.9 7693.2 8991.6 8262.1 6204.3 8757.7 10443.0 7648.6 False True 10319.71014022053 7713.199112947372 6293.152150399432 8258.983591762875 8462.731766165758 7908.749242895785 6525.528296126948 9164.614713555691 9266.799370334831 8970.650318881126 1.1503859556870641 0.8598260815843961 0.7015268600040975 0.9206672089736506 0.943379963028286 0.8816249615983485 0.7274309068086439 1.0216221107477923 1.0330131084064642 1.0 13.130996860421627 -7.891663849806833 24.38636376903046 1.0205672197869804 0.8789438350389779 0.21932472234068434 0.11617190454839674 10.671675334916515 2351.8519079130397 0.06449130487767647 0.030980598616599533 1.2833235092432464e-08 7.891663849806833 -0.1416233847480025 (ac)AEPPS(ph)PVHCVAAAAPTATVSEK ddPTM_PC-9_AZD4547_30min_R2 1 AEPPSPVHCVAAAAPTATVSEK 22 0 Q6PCB5 Q6PCB5 RSBN1L Round spermatid basic protein 1-like protein 1 AEPPS(1)PVHCVAAAAPTATVSEK 65.467 0.00018443 5049100.0 12237.0 16807.0 13380.0 12489.0 12548.0 16849.0 16240.0 20642.0 16144.0 14883.0 True False 16128.111454588012 22239.534071201662 13202.5724576633 9609.854003126538 10805.926794246172 15795.429366459903 17685.328538951308 17452.253205971403 16997.33888137079 14361.950700032636 1.1229749907546587 1.5485037190074136 0.9192743195834323 0.6691189939194473 0.7523996579532624 1.0998108610986952 1.2314015629444488 1.2151728947190819 1.183497927014341 1.0 13.8099640948756 -5.275535358916192 24.754851824058537 1.0064261581397678 1.3357393743780712 0.2938713434326484 0.20266819801920882 845.7639478219478 1485300.1697907455 0.06012535046188931 0.1261433568112138 5.302304211475508e-06 5.275535358916192 0.32931321623830345 (ac)AEPPS(ph)PVHCVAAAAPTATVSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEPPSPVHCVAAAAPTATVSEK 22 0 Q6PCB5 Q6PCB5 RSBN1L Round spermatid basic protein 1-like protein 1 AEPPS(1)PVHCVAAAAPTATVSEK 84.508 0.0005085 0.0 8134.9 15650.0 14669.0 9386.9 12650.0 7016.8 11184.0 5813.4 4979.0 7308.2 True False 9511.977898401195 17203.62857275319 15018.764592492293 8860.982425740407 10171.323308784822 6648.826655629563 10124.57055485192 5660.804409806447 5051.808455657432 8633.118808320627 1.101800879797174 1.992747806988626 1.739668470450929 1.0263941250524855 1.1781748328288577 0.7701534987820859 1.1727593213583285 0.6557079238097067 0.58516609904505 1.0 13.075666127548933 -5.843135088057069 4.294956830482925 0.9016109002518292 1.6503850348631708 0.5722275296925119 0.2774326649282812 0.148247816690535 5.090321421227775 0.08011289692438892 0.12479984948035817 1.435042991295292e-06 5.843135088057069 0.7487741346113416 (ac)AEPPS(ph)PVHCVAAAAPTATVSEK ddPTM_PC-9_Lapatinib_30min_R1 1 AEPPSPVHCVAAAAPTATVSEK 22 0 Q6PCB5 Q6PCB5 RSBN1L Round spermatid basic protein 1-like protein 1 AEPPS(1)PVHCVAAAAPTATVSEK 69.331 0.00033123 4344200.0 8241.7 12421.0 13508.0 12434.0 17568.0 18347.0 17776.0 17910.0 14814.0 14683.0 True False 8124.171846657322 12392.239937643964 12397.424382387895 13348.437838608059 16534.684780016916 17562.341578945903 18696.354301364 18742.163983669514 13145.491321664285 17220.9369861323 0.4717613131735844 0.7196031172765573 0.7199041720187067 0.7751284293855385 0.9601501238481965 1.0198249719564347 1.0856757861909505 1.088335901743455 0.7633435586141513 1.0 14.071876021033955 -5.626385308117685 0.8579580012200808 1.008685175083399 0.5074364123172833 0.7274707341868801 0.0997160997008073 0.47760267559632835 0.5857719598152336 0.043191476428190496 0.18013612539613272 2.3638215732146127e-06 5.626385308117685 -0.5012487627661156 (ac)AEPPS(ph)PVHCVAAAAPTATVSEKEPFGK ddPTM_PC-9_AZD4547_30min_R2 4 AEPPSPVHCVAAAAPTATVSEKEPFGK 27 1 Q6PCB5 Q6PCB5 RSBN1L Round spermatid basic protein 1-like protein 1 AEPPS(0.997)PVHCVAAAAPT(0.002)AT(0.001)VSEKEPFGK;AEPPS(0.995)PVHCVAAAAPT(0.003)AT(0.001)VS(0.001)EKEPFGK;AEPPS(1)PVHCVAAAAPTATVSEKEPFGK;AEPPS(0.989)PVHCVAAAAPT(0.005)AT(0.005)VS(0.001)EKEPFGK 61.736000000000004 8.3663e-06 220186700.0 216677.9 190482.0 259738.0 384238.0 323517.0 319088.0 244099.0 310856.0 229423.0 275000.0 True False 285576.96501970105 252051.58142146928 256293.70441020586 295657.8655179224 278602.2488599092 299135.3769176188 265823.33811757853 262820.34796024795 241549.83140366254 265372.3337034858 1.0761369168904809 0.9498035379343633 0.9657890889883648 1.1141246767957214 1.049854161403298 1.1272289493894951 1.001699515574207 0.9903833767913075 0.91022989485241 1.0 18.017658445335876 -7.732489601058744 2.8243327971174788 0.9573990820200986 1.0429084662096952 0.2782116579455479 0.05756266754716346 0.37637198572193836 6.061605309505739 0.03671320185896086 0.017152951801762756 1.8514432254589306e-08 7.732489601058744 0.08550938418959664 (ac)AEPPS(ph)PVHCVAAAAPTATVSEKEPFGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AEPPSPVHCVAAAAPTATVSEKEPFGK 27 1 Q6PCB5 Q6PCB5 RSBN1L Round spermatid basic protein 1-like protein 1 AEPPS(1)PVHCVAAAAPTATVSEKEPFGK;AEPPS(1)PVHCVAAAAPTATVSEKEPFGK;AEPPS(1)PVHCVAAAAPTATVSEKEPFGK;AEPPS(1)PVHCVAAAAPTATVSEKEPFGK 73.389 4.8648e-12 169641000.0 279359.0 248622.0 292851.0 375064.0 372915.0 357444.0 379717.0 360877.0 327297.0 254447.0 True False 326648.9611082446 273303.549074443 299833.6784836026 354050.38005389355 299844.9827427265 338699.0073958008 343747.45684698806 351404.3611307873 332083.0994399093 300576.2268986556 1.08674250282069 0.9092653530666348 0.9975295836842634 1.1779054641379463 0.997567192311002 1.1268323210072064 1.1436282250055936 1.1691023097753812 1.1048215717734615 1.0 18.197371382920302 -5.669987910949902 8.225870724217764 1.1080601953126135 0.9875052078811846 0.3116451197807203 0.0708020995805816 0.2638709129054267 20.945139426457448 0.018595287288336943 0.03226056230744655 2.138021602785528e-06 5.669987910949902 -0.1205549874314289 (ac)AEPPS(ph)PVHCVAAAAPTATVSEKEPFGK ddPTM_PC-9_Lapatinib_30min_R1 4 AEPPSPVHCVAAAAPTATVSEKEPFGK 27 1 Q6PCB5 Q6PCB5 RSBN1L Round spermatid basic protein 1-like protein 1 AEPPS(1)PVHCVAAAAPTATVSEKEPFGK;AEPPS(1)PVHCVAAAAPTATVSEKEPFGK;AEPPS(1)PVHCVAAAAPTATVSEKEPFGK;AEPPS(1)PVHCVAAAAPTATVSEKEPFGK 108.57 2.277e-11 192566000.0 202949.0 165469.0 209586.0 180077.0 188185.0 188182.0 177916.0 156292.0 196273.0 155199.0 True False 200054.9100437113 165085.8666968853 192354.6481053565 193320.4632992624 177116.328285945 180133.89453366763 187127.61993032627 163553.89689199746 174166.6678936828 182024.94036033188 1.0990521938789695 0.9069409190305766 1.0567488593847425 1.0620548091737878 0.973033299367274 0.9896110619626036 1.0280328594526291 0.8985246558423828 0.9568285947459011 1.0 17.47377661095443 -7.743358123467659 24.99245636489264 0.9457574510390239 1.0128773521356578 0.21899789117864088 0.0553589115209753 330.5580959068604 456908.598648047 0.025134638782713666 0.014474625002418053 1.8056845268454755e-08 7.743358123467659 0.0671199010966339 (ac)AEPVS(ph)PLKHFVLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEPVSPLKHFVLAK 14 1 Q8IWA4-3;Q8IWA4;C9JXQ1;Q8IWA4-2 Q8IWA4-3 MFN1 Mitofusin-1 1 AEPVS(1)PLKHFVLAK 55.31399999999999 0.023992 2095500.0 15884.0 8670.3 12270.0 17045.0 18234.0 18421.0 15708.0 19940.0 18343.0 12193.0 True False 18572.847476699724 9531.030083983514 12562.563334234126 16090.0239106356 14661.178593864224 17454.97033168284 14220.024523928294 19416.596128176374 18611.231673453363 14403.494380265103 1.289468165596485 0.6617165135317733 0.8721885816435404 1.1170916921855636 1.0178903956773286 1.211856641927025 0.9872621287936774 1.3480476067515919 1.2921330881312716 1.0 13.814131240765722 -6.4037263081704054 1.1490824524813943 1.1894978737629176 0.928535506585699 0.17929324930858626 0.1848833449642049 0.6984639373464617 1.927797421125721 0.08127051706154678 0.10421700277527907 3.9470596691076376e-07 6.4037263081704054 -0.26096236717721855 (ac)AEQLS(ph)PGK ddPTM_PC-9_AZD4547_30min_R2 2 AEQLSPGK 8 0 O15541 O15541 RNF113A RING finger protein 113A 1 AEQLS(1)PGK;AEQLS(1)PGK 85.355 0.0092276 15678600.0 255601.0 311310.0 279040.0 231784.0 225143.0 283590.0 306200.0 297800.0 304230.0 247485.0 True False 336876.801168927 411934.8695011478 275339.7472785032 178349.77982710244 193885.78070106532 265857.0724692489 333451.20681200136 251781.85276321444 320310.9767021449 238820.62547857116 1.4105850384315075 1.7248714120720272 1.1529144383017655 0.7467938728897825 0.8118468842987863 1.1132081742793345 1.3962412423290516 1.0542718086374254 1.3412199053589937 1.0 17.865567913178054 -5.365875037486956 5.621307414242691 1.065665932046337 1.5637010313717599 0.4872156681246106 0.20243717975570427 0.18747800780715307 8.26600752839619 0.05767345457687993 0.12299724213266545 4.306505066733097e-06 5.365875037486956 0.4980350993254228 (ac)AEQLS(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEQLSPGK 8 0 O15541 O15541 RNF113A RING finger protein 113A 1 AEQLS(1)PGK 77.66199999999999 0.015628 5008700.0 80037.0 109320.0 96379.0 100660.0 104420.0 82618.0 117150.0 90931.0 79094.0 71264.0 True False 93585.68329719322 120172.56712928963 98677.04087939285 95020.34654412317 83959.65058524192 78285.3666393233 106052.70390744819 88544.15759935827 80250.6001188531 84183.59907448647 1.1116854627988486 1.4275056952953482 1.1721646729796198 1.128727538247067 0.9973397610495793 0.9299360861259406 1.2597786869816734 1.0517981955251585 0.9532806983916972 1.0 16.36125156962659 -5.758561248898885 2.3997638598047084 1.0432430465185527 1.2716368803660119 0.40092268841242285 0.11274028574930686 0.2823326281470195 3.3151764140870674 0.03333056132110157 0.06184058012948592 1.7435674434114438e-06 5.758561248898885 0.22839383384745915 (ac)AEQLS(ph)PGKAVDQVCTFLFK ddPTM_PC-9_Lapatinib_30min_R1 1 AEQLSPGKAVDQVCTFLFK 19 1 O15541 O15541 RNF113A RING finger protein 113A 1 AEQLS(0.999)PGKAVDQVCT(0.001)FLFK 52.185 0.00015773 4339100.0 19722.0 13192.0 15431.0 14239.0 15540.0 16609.0 11530.0 13299.0 18307.0 14930.0 True False 19440.760663428155 13161.45473451407 14162.322745382555 15286.18355991155 14625.96775281551 15898.671787470039 12126.966983276723 13916.920090386417 16245.07287874363 17510.630607025487 1.1102261877209765 0.7516265421779572 0.8087842787169784 0.8729659087079673 0.8352621947805459 0.9079439880989375 0.6925488439240578 0.7947697831512003 0.9277263191324417 1.0 14.095943419759896 -4.75075532845066 24.992629355839867 0.83397370719152 1.1102267716513898 0.4664256034590567 0.08503026868396463 388.6946043899103 909192.56489914 0.020365685270568264 0.2895776799421015 1.7751893001588535e-05 4.75075532845066 0.27625306445986986 (ac)AES(ph)QLNCLDEAHVNEK ddPTM_PC-9_AZD4547_30min_R2 2 AESQLNCLDEAHVNEK 16 0 Q8NEG4 Q8NEG4 FAM83F Protein FAM83F 1 AES(1)QLNCLDEAHVNEK;AES(1)QLNCLDEAHVNEK 113.61 4.5741000000000006e-09 6563900.0 53387.0 48569.0 73287.0 87271.0 65307.0 57669.0 59363.0 53962.0 53973.0 56998.0 True False 70362.95548141621 64267.97943143894 72315.16649512482 67152.01927350923 56240.25033087625 54062.948313512796 64646.191998630995 45623.41282340025 56825.90259193663 55002.517368840956 1.279267910767971 1.1684552363388168 1.3147610319394494 1.2208899244228226 1.0225032056939356 0.9829177081291114 1.1753315137400093 0.8294786312679937 1.0331509412718012 1.0 15.74721002932186 -6.251772789045678 4.1221921842881715 1.0039579436394903 1.2486642604262668 0.6534665364303831 0.08541362629649903 0.13407021994805093 5.529483209505302 0.02602879325600151 0.032265893834303075 5.600505279292962e-07 6.251772789045678 0.24470631678677646 (ac)AES(ph)QLNCLDEAHVNEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AESQLNCLDEAHVNEK 16 0 Q8NEG4 Q8NEG4 FAM83F Protein FAM83F 1 AES(1)QLNCLDEAHVNEK 110.98 1.0191e-07 3891100.0 21033.0 21934.0 22516.0 18129.0 19862.0 19863.0 17181.0 19934.0 18160.0 10762.0 True False 24593.471479314096 24111.462563244 23052.866832405514 17113.29090501101 15970.183680559998 18821.34931318692 15553.491300331802 19410.753621818843 18425.555644655346 12713.06540805487 1.9345036535194666 1.8965892008993535 1.8133208704959112 1.3461183715902383 1.2562024317472205 1.4804729393795066 1.223425727871837 1.52683503142526 1.4493401121794827 1.0 13.634024318293571 -5.715703692114261 4.188639467547756 1.3450646566913633 1.9007799467380202 0.7591294893306687 0.14367438847860306 0.09893596466621414 3.6452956748995153 0.03856253511452852 0.06704111650855964 1.924404252327873e-06 5.715703692114261 0.5557152900466569 (ac)AES(ph)QLNCLDEAHVNEK ddPTM_PC-9_Lapatinib_30min_R1 2 AESQLNCLDEAHVNEK 16 0 Q8NEG4 Q8NEG4 FAM83F Protein FAM83F 1 AES(1)QLNCLDEAHVNEK;AES(1)QLNCLDEAHVNEK 116.74 2.153e-08 5509800.0 25758.0 34823.0 34718.0 32221.0 30280.0 28182.0 27838.0 28673.0 32872.0 18421.4 True False 25390.686196561328 34742.36948301872 31863.620055355546 34590.63982610505 28498.989932770506 26976.7215554507 29279.3154276199 30005.252255932777 29169.609202494143 21605.51444502743 1.175194706016596 1.608032503526653 1.4747910833795974 1.601009775264397 1.3190609279534942 1.2486035277748022 1.3551778876692573 1.388777496239557 1.3501001920927465 1.0 14.399111962638807 -6.409295317327644 7.710204891773292 1.29672709181728 1.4753048811531346 0.2647520642940334 0.15120175290050675 0.39899994492535257 24.489398524913156 0.04515669324414367 0.05116991879760921 3.8967691887981553e-07 6.409295317327644 0.17857778933585466 (ac)AESDWDTVTVLR ddPTM_PC-9_Lapatinib_30min_R1 2 AESDWDTVTVLR 12 0 O60869-2;O60869-3;O60869 O60869-2 EDF1 Endothelial differentiation-related factor 1 0 ; 112.71 0.00020299999999999997 351380.0 8375.12 2940.5 5498.99 3842.32 5006.3 3844.91 3058.0 978.48 3696.0299999999997 2212.0 False True 8255.689252991093 2933.691452913781 5046.884268915248 4124.897030403774 4711.839276764497 3680.4721622229767 3216.328277091085 1023.9437529168594 3279.7441804786577 2594.341252695272 3.182190949018069 1.1308039949894628 1.9453432595546243 1.5899593109111614 1.816198725541348 1.4186538329910603 1.2397475751309233 0.3946835258673391 1.264191507987362 1.0 11.3411525449727 -1.5228787452803423 0.28358129314788033 0.899770446012616 13.760431545403991 0.5435897790872622 0.4716565816143006 43.507578985128816 0.6149019988474002 0.5175195902785369 278.4397943588277 0.029999999999999673 1.5228787452803423 12.860661099391375 (ac)AESSESFT(ph)MASSPAQRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AESSESFTMASSPAQRR 17 1 P49736;F8WDM3 P49736 MCM2 DNA replication licensing factor MCM2 1 AES(0.101)S(0.101)ES(0.037)FT(0.319)MAS(0.221)S(0.221)PAQRR 43.861000000000004 0.0021649 34074000.0 1458.4 3381.5 1597.3 2852.3 3211.1 3056.8 1282.0 1680.2 3374.7 1120.1 True False 1705.2783152870109 3717.192972445043 1635.3856897939834 2692.494878281369 2581.908006074222 2896.496026811146 1160.5596791237635 1636.0965303190546 3424.048603194846 1323.165263293278 1.288787094548323 2.809318741631091 1.2359647998343062 2.034889331646988 1.951311810928296 2.189065952050421 0.877108635874555 1.2365020271518539 2.587770929439756 1.0 10.36977755009079 -7.235060813111201 24.98052265953217 1.4450536676149974 1.9345226198982155 0.13822510162456236 0.6012740254553195 1517.0320495126175 1436632.5243562593 0.2214163394047459 0.17145590869300248 5.8202171309868765e-08 7.235060813111201 0.4894689522832181 (ac)AESSESFTMAS(ph)SPAQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AESSESFTMASSPAQR 16 0 P49736;F8WDM3 P49736 MCM2 DNA replication licensing factor MCM2 1 AESSESFT(0.009)MAS(0.847)S(0.143)PAQR;AESSESFTMAS(0.761)S(0.239)PAQR;AESSESFTMAS(0.793)S(0.207)PAQR 188.39 1.1252999999999998e-77 115039000.0 33109.6 21283.0 55581.9 49789.3 72799.3 61579.2 50382.8 66865.5 57572.6 34369.0 True False 38714.40133559162 23395.835585553104 56907.183291529574 46999.766940088535 58534.799759147725 58349.878348013925 45610.17644411602 65110.35147485344 58414.49035834165 40599.82763514567 0.9535607314272951 0.5762545544725478 1.4016607115412298 1.1576346422565273 1.4417499572948052 1.437195223398011 1.1234081300540568 1.6037100467512817 1.438786658980161 1.0 15.309185982072009 -5.269381518813415 24.86568660764079 1.3420048061446956 0.7649076348763292 0.5748139771822336 0.1924447200507936 314.7999404851522 985595.303924099 0.047969805214927545 0.1027971259168945 5.377971311670668e-06 5.269381518813415 -0.5770971712683665 (ac)AESSESFTMAS(ph)SPAQR ddPTM_PC-9_Lapatinib_30min_R1 2 AESSESFTMASSPAQR 16 0 P49736;F8WDM3 P49736 MCM2 DNA replication licensing factor MCM2 1 AESSESFTMAS(0.731)S(0.269)PAQR;AESSES(0.001)FT(0.071)MAS(0.542)S(0.387)PAQR 146.2 1.3623e-07 72602000.0 17349.5 26397.0 26242.0 19384.0 26409.0 26707.5 19149.4 15683.9 17917.2 10934.0 True False 17102.092948491365 26335.879368326838 24084.484057049387 20809.564023128405 24855.674542091678 25565.28248322331 20140.86223326619 16412.631250891925 15899.176259519609 12823.9273313608 1.33360806768363 2.0536516378974388 1.8780895613897466 1.6227138134383219 1.9382264028670335 1.9935610848872827 1.570568961663709 1.2798443742546002 1.2398055485419288 1.0 13.646550534937576 -7.710088151608375 2.232658768828644 1.146738043696699 1.816028502340078 0.6582190413577181 0.20388074088677713 0.18875883864779275 1.87380306130788 0.13036103661167703 0.05806849893274653 1.9494488671344754e-08 7.710088151608375 0.669290458643379 (ac)AESSESFTMAS(ph)SPAQRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AESSESFTMASSPAQRR 17 1 P49736;F8WDM3 P49736 MCM2 DNA replication licensing factor MCM2 1 AESSES(0.004)FT(0.008)MAS(0.878)S(0.11)PAQRR 111.64 1.0022e-53 0.0 1381.4 2218.0 1432.8 4167.0 1263.6 599.43 897.49 1009.4 1814.1 1362.8 True False 1615.243736106332 2438.1883817486614 1466.9633859242585 3933.536499596274 1016.006650828498 567.9948355637939 812.4732499350903 982.9043195477051 1840.6277805599802 1609.8648520811366 1.0033412022246724 1.5145298554699904 0.9112338740906458 2.4433954778944544 0.6311130089678432 0.3528214401535162 0.5046841347488106 0.6105508287090469 1.1433430440949917 1.0 10.652723864047783 -6.40419699297593 19.380068579592383 0.6594204281603303 1.4449885251299015 0.4129708615860024 0.4419442613629724 3.508942627231776 559.9535663453812 0.1334323106017304 0.15129762587573786 3.9427841954184337e-07 6.40419699297593 0.7855680969695712 (ac)AESSESFTMASS(ph)PAQR ddPTM_PC-9_AZD4547_30min_R2 5 AESSESFTMASSPAQR 16 0 P49736;F8WDM3 P49736 MCM2 DNA replication licensing factor MCM2 1 AESSESFTMAS(0.03)S(0.969)PAQR;AESSESFTMAS(0.213)S(0.786)PAQR;AESSESFT(0.001)MAS(0.06)S(0.939)PAQR;AES(0.001)SESFT(0.002)MAS(0.387)S(0.609)PAQR;AESSESFTMAS(0.397)S(0.603)PAQR 192.4 1.1665e-68 164306000.0 17912.4 15318.800000000001 21516.8 21094.0 31904.5 26914.0 17137.7 26591.0 8702.9 23256.0 True False 23608.170598934565 20270.30252453883 21231.473173172642 16231.10419905127 27475.110886757015 25231.06332535473 18662.92209987598 22481.971950391704 9162.917526677513 22441.814518575473 1.0519724498833942 0.9032381275480534 0.9460675809257308 0.7232527559487896 1.2242820590115562 1.124288025126959 0.831613775456007 1.001789402179712 0.4082966428179508 1.0 14.453901708398002 -8.169968276312604 24.99999712222278 0.7039877461849335 0.9724092812410678 0.2488550244996276 0.18871639901527595 72.2012446320824 19729.097588903438 0.12266553596239879 0.04636320325028204 6.761323626838378e-09 8.169968276312604 0.2684215350561343 (ac)AESSESFTMASS(ph)PAQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AESSESFTMASSPAQR 16 0 P49736;F8WDM3 P49736 MCM2 DNA replication licensing factor MCM2 1 AESSESFTMAS(0.005)S(0.995)PAQR 148.18 8.6586e-05 10741000.0 5569.2 6929.4 7917.2 5981.6 8568.8 6938.2 7988.6 6913.3 5861.8 6985.0 True False 6511.95556328608 7617.305037190798 8105.976074148204 5646.470344608853 6889.805151645479 6574.348577996955 7231.861975544534 6731.833200246832 5947.517735563917 8251.325206770423 0.7892011767931355 0.9231614130225536 0.9823847528754586 0.6843107262304702 0.8349937711814118 0.7967627518307646 0.8764485454543237 0.8158487311496572 0.720795458489968 1.0 13.010410127135623 -5.74065356403348 24.99975989881906 0.8129805080006457 0.9007402737348491 0.13471574512714757 0.09188245854039791 441.13117456712394 530558.3502343408 0.023867412116675625 0.04128423573409913 1.8169644742971781e-06 5.74065356403348 0.08775976573420341 (ac)AESSESFTMASS(ph)PAQR ddPTM_PC-9_Lapatinib_30min_R1 3 AESSESFTMASSPAQR 16 0 P49736;F8WDM3 P49736 MCM2 DNA replication licensing factor MCM2 1 AESSESFT(0.002)MAS(0.123)S(0.875)PAQR;AESSESFTMAS(0.325)S(0.675)PAQR;AESSESFTMAS(0.337)S(0.663)PAQR 220.72 3.3894e-82 83352300.0 6885.700000000001 7618.5 10515.4 5218.000000000001 6348.8 9473.6 5396.9 5334.5 8608.0 6590.5 True False 6787.508655317268 7600.859831329245 9650.86440261783 5601.749126737724 5975.37606622105 9068.43621204022 5676.325074765495 5582.360344549692 7638.476393741467 7729.659143710753 0.8781122853056118 0.9833369997322191 1.2485498031915505 0.7247084279642 0.7730452216748681 1.1732000135373066 0.7343564533998946 0.7222000661040515 0.9882035225261548 1.0 12.916189081409826 -5.77888569452929 24.99999307262953 0.8645809907354577 1.0313335843853069 0.1711294721344927 0.1634025458337227 412.3845913147196 590932.2642165842 0.04668475635775563 0.06942536235698267 1.663850514994227e-06 5.77888569452929 0.16675259364984918 (ac)AESSESFTMASS(ph)PAQRR ddPTM_PC-9_AZD4547_30min_R2 3 AESSESFTMASSPAQRR 17 1 P49736;F8WDM3 P49736 MCM2 DNA replication licensing factor MCM2 1 AESSES(0.011)FT(0.003)MAS(0.049)S(0.937)PAQRR;AESSESFTMAS(0.231)S(0.769)PAQRR;AES(0.007)S(0.007)ES(0.027)FT(0.076)MAS(0.223)S(0.659)PAQRR 119.04 2.8916999999999994e-37 81076000.0 3332.0 7144.7 8492.300000000001 13739.7 11876.5 10779.900000000001 6696.1 9023.8 8691.6 11026.400000000001 True False 4391.506690094571 9454.084552776498 8379.68655322975 10572.224441248924 10227.652978312452 10105.83114888131 7292.039927935461 7629.379056295157 9151.020231746923 10640.36909217495 0.4127212742388923 0.8885109596178521 0.7875372067113977 0.9935956497057851 0.961212237067414 0.949763214164559 0.6853183254045305 0.7170220309280334 0.8600284588320051 1.0 13.37726057533356 -4.759487671255181 24.999418815768944 0.8632316759991631 0.4127207041598502 0.6272180824473284 0.10592338540215039 36.83146747490129 471650.2649123473 0.028373308334693464 0.17950571023974776 1.7398520882305443e-05 4.759487671255181 -0.4505109718393129 (ac)AESSESFTMASS(ph)PAQRR ddPTM_PC-9_Lapatinib_30min_R1 3 AESSESFTMASSPAQRR 17 1 P49736;F8WDM3 P49736 MCM2 DNA replication licensing factor MCM2 1 AES(0.01)S(0.01)ES(0.001)FT(0.049)MAS(0.259)S(0.672)PAQRR;AESSES(0.009)FT(0.17)MAS(0.186)S(0.635)PAQRR;AES(0.002)S(0.002)ESFT(0.006)MAS(0.071)S(0.918)PAQRR 75.143 1.9823e-05 63980000.0 25010.1 12864.9 14808.1 18535.8 18792.8 17110.699999999997 9892.0 13779.199999999999 17105.0 6770.5 True False 24653.45138770939 12835.112114467101 13590.635178919018 19898.984565616163 17687.444452066353 16378.915247989842 10404.159358072267 14419.431935442715 15178.454776364755 7940.771903875824 3.1046668618797937 1.6163557233273997 1.7115005119698177 2.505925721894069 2.2274212968431018 2.062635150116254 1.3102201503853907 1.815872828232821 1.911458351921213 1.0 12.955063539859747 -8.991795454663217 0.10664993847163934 2.0305059364265814e-13 3.097395829654124 0.4354957255111964 0.4267410537924889 21.79324330133104 1.0737097628881083 18.22639562953672 11.17401625668904 1.0190712403182296e-09 8.991795454663217 3.0973958296539212 (ac)AETLEFNDVYQEVK ddPTM_PC-9_Lapatinib_30min_R1 2 AETLEFNDVYQEVK 14 0 Q08945 Q08945 SSRP1 FACT complex subunit SSRP1 0 ; 175.15 1.3050999999999997e-34 2070630.0 13604.099999999999 13005.599999999999 16558.3 12658.8 13128.5 13858.400000000001 12202.3 14877.6 12147.400000000001 11917.099999999999 False True 13410.103039313593 12975.486332261675 15196.940490886403 13589.77038051888 12356.307441624087 13265.708537508262 12834.075387687557 15568.867609349063 10779.231894207149 13976.954856462395 0.9594438257138169 0.9283485899120809 1.087285510109517 0.9722983668531707 0.8840486049013041 0.9491129272249684 0.9182311540309215 1.1138955351315762 0.7712146175547856 1.0 13.77076245614134 -6.006223929092845 24.916743128577732 0.9430497752167736 0.9927638434171808 0.06517866571003139 0.08960283533408712 852.3485384637257 3412307.030946001 0.024598561213598154 0.03511812635528548 9.857710754374347e-07 6.006223929092845 0.049714068200407247 (ac)AEVEETLKR ddPTM_PC-9_Lapatinib_30min_R1 1 AEVEETLKR 9 1 Q9NP97;Q8TF09;H3BNG9;H3BPA0;Q7Z4M1;Q9NP97-2 Q9NP97 DYNLRB1;DYNLRB2 Dynein light chain roadblock-type 1;Dynein light chain roadblock-type 2 0 54.776 0.024942 2357500.0 11585.0 12581.0 17036.0 13055.0 14289.0 16169.0 12206.0 13507.0 16158.0 11519.0 False True 11419.7957755712 12551.869467474336 15635.365840861718 14015.108250203337 13448.549113254881 15477.489561779938 12837.966955583312 14134.584529727761 14338.115888716864 13510.043801897296 0.8452819208452491 0.9290768891298192 1.1573142226723165 1.037384367934848 0.9954482243326421 1.1456283775783422 0.950253540538514 1.0462278832687986 1.0612930719516451 1.0 13.72174473168733 -5.0383130357799555 6.122344978718979 1.048538612761907 0.863454882293909 0.5509831492929995 0.06063852699358164 0.11562227311920117 12.770932544849298 0.014939279934067146 0.04389496570997048 9.155603241114253e-06 5.0383130357799555 -0.18508373046799798 (ac)AFAETYPAAS(ph)SLPNGDCGRPR ddPTM_PC-9_AZD4547_30min_R2 1 AFAETYPAASSLPNGDCGRPR 21 1 P30520 P30520 ADSS Adenylosuccinate synthetase isozyme 2 1 AFAET(0.001)Y(0.001)PAAS(0.499)S(0.499)LPNGDCGRPR 59.11600000000001 0.00015574 4321000.0 0.0 0.0 1515.6 0.0 0.0 0.0 0.0 0.0 0.0 1027.9 True False 0.0 0.0 1495.5021537245516 0.0 0.0 0.0 0.0 0.0 0.0 991.9135338684106 0.0 0.0 1.5076940707645876 0.0 0.0 0.0 0.0 0.0 0.0 1.0 9.954070554644805 -11.327380687616682 6.888657885621644 1.037023905823624 0.17737577306580307 0.23554327525235785 0.44960472552651426 0.20675081959782196 0.005867519013351058 0.3520579402007767 0.1099055231011253 4.705646647484635e-12 11.327380687616682 -0.8596481327578208 (ac)AFAETYPAASS(ph)LPNGDCGRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AFAETYPAASSLPNGDCGRPR 21 1 P30520 P30520 ADSS Adenylosuccinate synthetase isozyme 2 1 AFAETYPAAS(0.187)S(0.813)LPNGDCGRPR;AFAET(0.007)Y(0.006)PAAS(0.255)S(0.733)LPNGDCGRPR 82.069 4.5908999999999995e-06 6992500.0 1021.6 2465.3 1852.21 1704.6 4326.6 1842.78 1789.87 2572.44 3031.5 1215.2 True False 1194.5367024802592 2710.0386913999 1896.3737109455408 1609.0967883877643 3478.833788757976 1746.141372771214 1620.3205560633778 2504.91617572548 3075.8299524654553 1435.5061404820924 0.8321362541013532 1.8878628345607604 1.3210488325105132 1.1209264405148236 2.423419650151872 1.2163942204975868 1.1287451236671258 1.7449707145691784 2.142679759929474 1.0 10.487343786453518 -4.744199506289937 24.473223545962632 1.5598014592847194 0.8321333952937646 0.18287145948460748 0.4576270908786271 1440.6603114322181 2044976.1149153672 0.11204396974742678 3.163139620959753 1.8021896604090874e-05 4.744199506289937 -0.7276680639909547 (ac)AFAETYPAASS(ph)LPNGDCGRPR ddPTM_PC-9_Lapatinib_30min_R1 1 AFAETYPAASSLPNGDCGRPR 21 1 P30520 P30520 ADSS Adenylosuccinate synthetase isozyme 2 1 AFAETYPAAS(0.093)S(0.907)LPNGDCGRPR 127.91 2.3023e-13 2989900.0 675.64 0.0 1028.3 996.26 541.0 949.58 477.59 1132.0 1143.2 410.46 True False 666.0052497027987 0.0 943.7571433527881 1069.528283825935 509.17944364692363 908.9686769790948 502.31727333418263 1184.596852569173 1014.4407775703129 481.40746409642884 1.3834543487040611 0.0 1.9604123611256428 2.2216695078323547 1.057689133679348 1.8881482834612278 1.0434347424940744 2.4606948186659006 2.1072394036813566 1.0 8.91111470036865 -5.278485161151931 24.875350603391517 1.7460536482552862 0.6917271007224782 0.32932343502254213 0.5843463643676386 711.9237159771621 1038928.2308081706 0.1479422738099373 0.3092183612456575 5.266412087107755e-06 5.278485161151931 -1.054326547532808 (ac)AFS(ph)QVQCLDDNHVNWR ddPTM_PC-9_AZD4547_30min_R2 3 AFSQVQCLDDNHVNWR 16 0 A6ND36 A6ND36 FAM83G Protein FAM83G 1 AFS(1)QVQCLDDNHVNWR;AFS(1)QVQCLDDNHVNWR;AFS(1)QVQCLDDNHVNWR 133.42 4.4178e-05 49170000.0 835.18 1585.49 3205.62 4538.83 2943.25 3659.29 841.38 3459.4 1097.3 2053.66 True False 1100.7498671768258 2097.9686365531948 3163.111384285099 3492.4728677244634 2534.630541693103 3430.4740178285397 916.2611900309637 2924.8292191036458 1155.3010378176514 1981.7619884854557 0.5554399940923603 1.058638044701094 1.5961106342051092 1.762306920819263 1.2789782811558377 1.7310222104170288 0.46234673757730527 1.4758731048923392 0.5829665946416603 1.0 10.95256798853316 -7.255356262198124 24.973812910791825 0.9199527046130241 1.3474328042296428 0.21609136685866115 0.4165166519967421 847.2908409563854 3478502.7219640296 0.16503407810082554 0.1244892604671445 5.554484226432878e-08 7.255356262198124 0.4274800996166187 (ac)AFS(ph)QVQCLDDNHVNWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 AFSQVQCLDDNHVNWR 16 0 A6ND36 A6ND36 FAM83G Protein FAM83G 1 AFS(1)QVQCLDDNHVNWR;AFS(1)QVQCLDDNHVNWR;AFS(1)QVQCLDDNHVNWR;AFS(1)QVQCLDDNHVNWR;AFS(1)QVQCLDDNHVNWR;AFS(1)QVQCLDDNHVNWR;AFS(1)QVQCLDDNHVNWR 155.26 2.8731999999999995e-29 39139500.0 6629.06 3864.06 1614.6100000000001 7496.599999999999 10090.29 5739.77 7643.32 8315.0 6906.360000000001 3631.44 True False 7751.228928096892 4247.658340117103 1653.1084258425242 7076.5898063051245 8113.170108252837 5438.766356912397 6919.289396755258 8096.740060470739 7007.352449450543 4289.791325536779 1.8069011613582355 0.990178313530343 0.385358704047375 1.6496349750578216 1.8912738388825103 1.267839375900609 1.6129664292911616 1.8874438046138755 1.6334949459514132 1.0 12.066691755012684 (ac)AFS(ph)QVQCLDDNHVNWR ddPTM_PC-9_Lapatinib_30min_R1 4 AFSQVQCLDDNHVNWR 16 0 A6ND36 A6ND36 FAM83G Protein FAM83G 1 AFS(1)QVQCLDDNHVNWR;AFS(1)QVQCLDDNHVNWR;AFS(1)QVQCLDDNHVNWR;AFS(1)QVQCLDDNHVNWR 145.46 9.352e-05 42338000.0 10895.8 4861.0 6757.099999999999 6754.6 13345.279999999999 10661.14 6637.200000000001 10889.67 6697.7 7795.96 True False 10740.42389395499 4849.7446531589485 6201.557321160295 7251.3558166850635 12560.336868229964 10205.187894531176 6980.841739930981 11395.643822894834 5943.334496092266 9143.481298536268 1.1746536732868222 0.5304046122930572 0.6782490299567923 0.7930629024030371 1.373693067020401 1.1161162320269493 0.7634774449692928 1.246313461013925 0.6500078364073105 1.0 13.15852784774477 -6.036038835008656 24.920221563351568 1.033704000820226 0.762636378718506 0.16716156024049367 0.2489536684383263 870.5261374643571 601952.1199322423 0.07158985990164402 0.0924580380226048 9.203672679928934e-07 6.036038835008656 -0.2710676221017201 (ac)AGLS(ph)DLELRR ddPTM_PC-9_Lapatinib_30min_R1 1 AGLSDLELRR 10 1 D6RBV0;Q8NC56 D6RBV0 LEMD2 LEM domain-containing protein 2 1 AGLS(1)DLELRR 46.406000000000006 0.022469 603590.0 2097.8 2922.9 3733.1 2222.0 2311.2 2786.7 3303.3 3809.9 3667.3 2145.0 True False 2067.8849873105955 2916.13220463244 3426.178928182723 2385.413292374708 2175.259759994028 2667.519337114981 3474.328710828968 3986.921862723758 3254.250055618973 2515.76039196716 0.8219721535935482 1.1591454472149532 1.3618860282253173 0.9481877924429324 0.8646529959449426 1.0603232905774287 1.38102528441203 1.5847780557536506 1.2935453098036742 1.0 11.296778807124902 -7.251100432200224 9.060694464108304 1.3637017321391247 1.0444758423774183 0.3107840367658363 0.1978962917893488 0.2214187005666483 166.6046224977521 0.07942316788759977 0.05902880337971782 5.6091824662015766e-08 7.251100432200224 -0.3192258897617064 (ac)AGTVVLDDVELR ddPTM_PC-9_Lapatinib_30min_R1 1 AGTVVLDDVELR 12 0 P25205 P25205 MCM3 DNA replication licensing factor MCM3 0 71.03 0.009291500000000001 0.0 973.45 737.01 545.41 757.77 664.26 547.12 0.0 0.0 639.99 0.0 False True 959.5684244911334 735.3034986267593 500.5684951434837 813.4989336466168 625.1895327854074 523.7209529990129 0.0 0.0 567.9075868065296 0.0 0.0 (ac)AHS(ph)PVAVQVPGMQNNIADPEELFTK ddPTM_PC-9_AZD4547_30min_R2 2 AHSPVAVQVPGMQNNIADPEELFTK 25 0 Q8NBY1;B4E0Y9;Q9P289-3;Q9P289 Q8NBY1 STK26 Serine/threonine-protein kinase 26 1 AHS(1)PVAVQVPGMQNNIADPEELFTK;AHS(1)PVAVQVPGMQNNIADPEELFTK 51.553999999999995 7.1605e-10 44549000.0 37691.0 36744.0 48193.0 66903.0 59944.0 56847.0 46849.0 70995.0 45509.0 55144.0 True False 49675.95397849771 48620.779431917304 47553.92933125319 51479.54699104615 51621.810308757835 53292.348103456956 51018.470241461226 60024.35405280198 47914.51283153514 53213.42534452731 0.9335229532185451 0.9136938491954768 0.8936453352395183 0.9674165242651592 0.9700899721176628 1.001483136227722 0.9587518546521865 1.1279926759868903 0.9004215105739827 1.0 15.69950265223984 -6.198795546322943 1.3833120738634679 1.0041926261857683 0.9134173280029801 0.28677223187184564 0.05476389082339516 0.4952516064793184 1.9094915297916137 0.019723437107442128 0.02926891157303197 6.327096432518956e-07 6.198795546322943 -0.09077529818278818 (ac)AHS(ph)PVAVQVPGMQNNIADPEELFTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AHSPVAVQVPGMQNNIADPEELFTK 25 0 Q8NBY1;B4E0Y9;Q9P289-3;Q9P289 Q8NBY1 STK26 Serine/threonine-protein kinase 26 1 AHS(1)PVAVQVPGMQNNIADPEELFTK;AHS(1)PVAVQVPGMQNNIADPEELFTK;AHS(1)PVAVQVPGMQNNIADPEELFTK;AHS(1)PVAVQVPGMQNNIADPEELFTK 73.11 2.1398000000000004e-09 63187000.0 81689.0 85640.0 105306.0 106080.0 123358.0 102883.0 117417.0 105494.0 106117.0 85919.0 True False 95517.33426870572 94141.77322495758 107816.89441522912 100136.68151600008 99186.88543281234 97487.6343648295 106294.411734536 102724.89428013217 107668.76037135984 101495.43456557019 0.941099810819546 0.9275468756591032 1.0622831940837203 0.9866126682900964 0.9772546504910383 0.9605125076029751 1.0472826899998686 1.0121134484504097 1.0608236797272041 1.0 16.631055308470458 -7.262382101912116 24.981850272284323 1.0310644093909411 0.9781648409838044 0.3356656076945226 0.03724040226898749 108.48891985399901 2874848.203305053 0.01556152424251323 0.011160197475583838 5.465348977811081e-08 7.262382101912116 -0.05289956840713672 (ac)AHS(ph)PVAVQVPGMQNNIADPEELFTK ddPTM_PC-9_Lapatinib_30min_R1 4 AHSPVAVQVPGMQNNIADPEELFTK 25 0 Q8NBY1;B4E0Y9;Q9P289-3;Q9P289 Q8NBY1 STK26 Serine/threonine-protein kinase 26 1 AHS(1)PVAVQVPGMQNNIADPEELFTK;AHS(1)PVAVQVPGMQNNIADPEELFTK;AHS(1)PVAVQVPGMQNNIADPEELFTK;AHS(1)PVAVQVPGMQNNIADPEELFTK 61.437 5.0885e-10 60718000.0 60243.2 56065.0 59662.5 56643.6 67327.8 64201.0 62337.0 56248.1 71514.8 51165.7 True False 59384.12092075015 55935.18493712334 54757.2795539101 60809.35930151032 63367.7111755477 61455.27288984066 65564.50484271647 58861.59206978457 63460.05013977034 60009.62307099027 0.9895766359088749 0.9321035873022074 0.9124749790401658 1.0133267997629976 1.0559591600931217 1.0240902999363988 1.0925665166260898 0.9808692182610846 1.0574978960407446 1.0 15.872906247663824 -5.901885867499268 5.36085040432863 1.0363639852200255 0.9440979442884573 0.5805838516886279 0.03437124502519605 0.1364943580159865 6.1108529622234045 0.009423839050059477 0.014192676164409708 1.2534705434621546e-06 5.901885867499268 -0.0922660409315682 (ac)AHS(ph)PVQSGLPGMQNLK ddPTM_PC-9_AZD4547_30min_R2 10 AHSPVQSGLPGMQNLK 16 0 B4DR80;Q9Y6E0-2 B4DR80 STK24 Serine/threonine-protein kinase 24;Serine/threonine-protein kinase 24 36 kDa subunit;Serine/threonine-protein kinase 24 12 kDa subunit 1 AHS(1)PVQSGLPGMQNLK;AHS(1)PVQSGLPGMQNLK;AHS(0.961)PVQS(0.039)GLPGMQNLK;AHS(1)PVQSGLPGMQNLK;AHS(0.999)PVQS(0.001)GLPGMQNLK;AHS(0.997)PVQS(0.003)GLPGMQNLK;AHS(1)PVQSGLPGMQNLK;AHS(1)PVQSGLPGMQNLK;AHS(1)PVQSGLPGMQNLK;AHS(0.999)PVQS(0.001)GLPGMQNLK 146.96 1.9754e-47 365500500.0 194361.0 173412.0 217497.8 306396.0 266659.0 265710.0 208613.0 297036.0 216663.0 264584.0 True False 256163.7550400567 229464.03774351324 214613.6370614618 235761.13597101154 229638.00071938857 249095.11169577175 227179.15286307014 251135.91140824129 228115.363853719 255320.99469310124 1.0033007874968076 0.8987276507336642 0.8405640018731317 0.9233911071606121 0.8994090007968835 0.9756154678748096 0.8897785829799938 0.9836085422983313 0.8934453828519519 1.0 17.961952647882114 -6.735052196903969 24.991573795391886 0.9437957125872164 0.9088255701070247 0.10430415224042977 0.050197104488476446 535.1970694835121 506889.66070966114 0.016215794115432745 0.016211212109999998 1.8405507764024495e-07 6.735052196903969 -0.0349701424801917 (ac)AHS(ph)PVQSGLPGMQNLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 AHSPVQSGLPGMQNLK 16 0 B4DR80;Q9Y6E0-2 B4DR80 STK24 Serine/threonine-protein kinase 24;Serine/threonine-protein kinase 24 36 kDa subunit;Serine/threonine-protein kinase 24 12 kDa subunit 1 AHS(1)PVQSGLPGMQNLK;AHS(0.998)PVQS(0.002)GLPGMQNLK;AHS(1)PVQSGLPGMQNLK;AHS(1)PVQSGLPGMQNLK;AHS(0.998)PVQS(0.002)GLPGMQNLK;AHS(0.99)PVQS(0.01)GLPGMQNLK;AHS(1)PVQSGLPGMQNLK 113.69 2.0036999999999996e-11 254725000.0 114533.7 121084.5 135492.0 134169.0 165414.0 138784.0 146636.0 144781.0 115512.0 106377.0 True False 133921.9932663107 133104.96894041737 138722.64313627122 126651.94591176663 133002.3141343348 131505.92272473127 132745.57652729526 140980.65215814963 117201.14447276588 125662.30802013102 1.0657292180631959 1.0592274727207305 1.1039320009469182 1.0078753757369876 1.058410562640851 1.0465025256711353 1.0563674869478723 1.1219008657358467 0.9326674507203093 1.0 16.939192457632977 -8.27069078796412 24.99552727089614 0.9663337202886432 1.0630717322024836 0.5898892662308958 0.032873941259155055 499.3790590164744 1349209.792891234 0.029138208598898152 0.007924303970981601 5.361782736179391e-09 8.27069078796412 0.09673801191384046 (ac)AHS(ph)PVQSGLPGMQNLK ddPTM_PC-9_Lapatinib_30min_R1 12 AHSPVQSGLPGMQNLK 16 0 B4DR80;Q9Y6E0-2 B4DR80 STK24 Serine/threonine-protein kinase 24;Serine/threonine-protein kinase 24 36 kDa subunit;Serine/threonine-protein kinase 24 12 kDa subunit 1 AHS(1)PVQSGLPGMQNLK;AHS(1)PVQSGLPGMQNLK;AHS(0.999)PVQS(0.001)GLPGMQNLK;AHS(0.809)PVQS(0.191)GLPGMQNLK;AHS(1)PVQSGLPGMQNLK;AHS(0.998)PVQS(0.002)GLPGMQNLK;AHS(0.998)PVQS(0.002)GLPGMQNLK;AHS(1)PVQSGLPGMQNLK;AHS(1)PVQSGLPGMQNLK;AHS(1)PVQSGLPGMQNLK;AHS(1)PVQSGLPGMQNLK;AHS(1)PVQSGLPGMQNLK 181.71 2.3326999999999995e-128 351982200.0 285398.0 316174.0 359330.0 316550.0 369197.0 351756.0 316208.0 307799.0 375524.0 302785.0 True False 281328.17218441685 315441.91852867283 329787.27445391164 339830.1429798447 347481.5583292298 336712.2158632852 332579.7030223729 322100.46521549305 333228.5326769717 355120.98381434823 0.7922037418422192 0.8882660639777372 0.9286617504594415 0.956941883100613 0.9784878229299112 0.9481619820002333 0.9365250666129052 0.90701614350078 0.9383521331174798 1.0 18.43795108500823 -4.725799896253685 1.503095429976427 0.9482847166878773 0.7161729054800766 0.8061026645063938 0.0239627389763855 0.5736054063148314 1.099024686517495 0.0071355535809005015 0.20757420334649584 1.8801829226371794e-05 4.725799896253685 -0.23211181120780067 (ac)AHS(ph)PVQSGLPGMQNLKADPEELFTK ddPTM_PC-9_AZD4547_30min_R2 1 AHSPVQSGLPGMQNLKADPEELFTK 25 1 B4DR80;Q9Y6E0-2 B4DR80 STK24 Serine/threonine-protein kinase 24;Serine/threonine-protein kinase 24 36 kDa subunit;Serine/threonine-protein kinase 24 12 kDa subunit 1 AHS(0.962)PVQS(0.038)GLPGMQNLKADPEELFTK 71.65100000000001 2.7492e-09 4522900.0 7369.0 4537.7 10778.0 28965.0 19409.0 8520.2 6076.7 8378.0 7143.3 10320.0 True False 9712.188715278171 6004.422785440098 10635.076677779904 22287.56675478903 16714.39537372682 7987.430547101416 6617.514527872255 7083.3726072874915 7520.880254664018 9958.699941163524 0.9752466459134472 0.6029323928740212 1.0679181761286558 2.2379996271064537 1.6783712203878285 0.8020555488458873 0.6644958244518709 0.71127482996138 0.7552070349641758 1.0 13.281741702572381 -6.868372554524684 8.494564643778046 0.7558637569473063 1.3100942625171283 0.2836739784792003 0.4168870923098273 0.38694965904039635 28.09362014272663 0.16869186724982724 0.14883965127026447 1.3540273771957933e-07 6.868372554524684 0.554230505569822 (ac)AKS(ph)PENSTLEEILGQYQR ddPTM_PC-9_AZD4547_30min_R2 1 AKSPENSTLEEILGQYQR 18 1 Q86SQ7-2;Q86SQ7-3;Q86SQ7-4;Q86SQ7 Q86SQ7-2 SDCCAG8 Serologically defined colon cancer antigen 8 1 AKS(0.951)PENS(0.038)T(0.011)LEEILGQYQR 64.22399999999999 0.00018812 4343100.0 9397.7 9870.1 13422.0 21702.0 20640.0 15027.0 14349.0 16682.0 12014.0 14923.0 True False 12385.973115696806 13060.4168046747 13244.015510220986 16698.939192557627 17774.49227233352 14087.35931448709 15626.033202303724 14104.180214224143 12649.035512932896 14400.55031220768 0.8601041520751419 0.9069387295291821 0.919688152403018 1.1596042394575399 1.2342925712544242 0.9782514563033684 1.085099726297069 0.9794195297014241 0.8783716759914387 1.0 13.813836324378345 -5.605771762283865 7.929745814658291 1.0507495641498448 0.8908680959580141 0.34351403457418717 0.0951743406081641 0.2815202779023378 23.29491450327038 0.028002298209705054 0.04866595976931578 2.4787243761797827e-06 5.605771762283865 -0.1598814681918307 (ac)AKS(ph)PENSTLEEILGQYQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AKSPENSTLEEILGQYQR 18 1 Q86SQ7-2;Q86SQ7-3;Q86SQ7-4;Q86SQ7 Q86SQ7-2 SDCCAG8 Serologically defined colon cancer antigen 8 1 AKS(0.999)PENS(0.001)TLEEILGQYQR;AKS(0.994)PENS(0.004)T(0.002)LEEILGQYQR;AKS(0.997)PENS(0.002)T(0.001)LEEILGQYQR 82.705 0.00013667 5195600.0 13439.9 9813.1 12284.599999999999 14284.5 15896.5 18217.1 17186.2 19214.899999999998 15144.8 15916.300000000001 True False 15715.009619875129 10787.27971548143 12577.511453604942 13484.185775973847 12781.69493898007 17261.763206628275 15558.198718687057 18710.52923486942 15366.264048853322 18801.799196638516 0.8358247769545768 0.573736566520189 0.6689525466187095 0.7171752891810811 0.6798123310063459 0.9180910308687066 0.8274845697463162 0.9951456793674611 0.817276255753257 1.0 14.19858310357308 -6.760844141331157 24.99999812648946 0.9060389535228248 0.6881315819033612 0.634942063414355 0.08194122186154557 9.95206551114527 417993.1455768737 0.026386815334812627 0.024890122232713103 1.7344263332653593e-07 6.760844141331157 -0.2179073716194636 (ac)AKS(ph)PENSTLEEILGQYQR ddPTM_PC-9_Lapatinib_30min_R1 1 AKSPENSTLEEILGQYQR 18 1 Q86SQ7-2;Q86SQ7-3;Q86SQ7-4;Q86SQ7 Q86SQ7-2 SDCCAG8 Serologically defined colon cancer antigen 8 1 AKS(0.94)PENS(0.03)T(0.03)LEEILGQYQR 64.22399999999999 0.0005105999999999999 2906300.0 7659.5 6305.7 7286.1 5911.5 6797.8 6506.7 5546.1 3963.2 6559.9 5571.2 True False 7550.274125419725 6291.0995390710505 6687.064983159348 6346.2514301859055 6397.966768989016 6228.423608858522 5833.249920724288 4147.34474037292 5821.0549831906 6534.174496842628 1.1555054321044052 0.9627994388749438 1.0233985924910023 0.9712399681478465 0.9791545622297921 0.9532074192184724 0.8927294371374634 0.6347159449716187 0.8908631053552956 1.0 12.673789267501732 -7.201297522913842 2.2080866285530867 0.8175569097796992 1.0118471124365709 0.36110093372567087 0.1003585966566621 0.3030902280903232 2.8928313694872343 0.04590164628941872 0.031241728234956814 6.290750735941458e-08 7.201297522913842 0.1942902026568717 (ac)ALVT(ph)VSRSPPGSGASTPVGPWDQAVQR ddPTM_PC-9_AZD4547_30min_R2 2 ALVTVSRSPPGSGASTPVGPWDQAVQR 27 1 Q8TE77;C9JUG3;Q8TE77-4;Q8TE77-2 Q8TE77 SSH3 Protein phosphatase Slingshot homolog 3 1 ALVT(0.321)VS(0.321)RS(0.321)PPGS(0.012)GAS(0.012)T(0.014)PVGPWDQAVQR;ALVT(0.294)VS(0.294)RS(0.294)PPGS(0.072)GAS(0.021)T(0.025)PVGPWDQAVQR 58.08 3.0167e-12 20695500.0 4431.0 2463.6 5409.3 11096.3 7722.400000000001 6486.099999999999 4225.4 5773.9 2364.1 6126.6 True False 5839.9658294745 3259.9105216762296 5337.5691476261645 8538.219471126034 6650.278058326963 6080.523141658003 4601.452414315569 4881.676426022589 2489.061499594194 5912.109598791906 0.9877972882417221 0.5513954819684613 0.9028197225431774 1.444191676160867 1.1248570323672444 1.028486201084721 0.7783097280970298 0.8257080394822386 0.4210107167334676 1.0 12.529457299100137 -7.365288332226294 3.360970825158978 0.7282620773640627 1.0068059400138794 0.19811114989276024 0.24553158333873606 0.45305782298406705 9.62577065296992 0.12195463851389256 0.07826753909883777 4.312326822997701e-08 7.365288332226294 0.2785438626498167 (ac)ALVT(ph)VSRSPPGSGASTPVGPWDQAVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALVTVSRSPPGSGASTPVGPWDQAVQR 27 1 Q8TE77;C9JUG3;Q8TE77-4;Q8TE77-2 Q8TE77 SSH3 Protein phosphatase Slingshot homolog 3 1 ALVT(0.69)VS(0.098)RS(0.071)PPGS(0.093)GAS(0.026)T(0.022)PVGPWDQAVQR;ALVT(0.315)VS(0.315)RS(0.315)PPGS(0.04)GAS(0.007)T(0.007)PVGPWDQAVQR 53.481 7.2532e-10 14062800.0 2351.27 3810.3 5909.0 4800.7 5278.4 6031.1 8098.3 5801.8 5056.7 3934.56 True False 2749.2935713006636 4188.561402604568 6049.892970007293 4531.732343079396 4244.135411311443 5714.818498855241 7331.170397385316 5649.508897515233 5130.644671163473 4647.864582040176 0.5915175717305137 0.9011797415074435 1.3016500079164737 0.9750138505735457 0.9131366321882991 1.2295578750159555 1.577320136587823 1.2155063465802152 1.103871375897828 1.0 12.182352320344048 -6.798801439597676 6.882011082514013 1.2625285487517581 0.9569173656455893 0.3055560002952812 0.21304742827262776 0.24837531397660984 33.10707669004422 0.0782798209267996 0.06999132572345092 1.58927320175705e-07 6.798801439597676 -0.30561118310616886 (ac)ALVT(ph)VSRSPPGSGASTPVGPWDQAVQR ddPTM_PC-9_Lapatinib_30min_R1 2 ALVTVSRSPPGSGASTPVGPWDQAVQR 27 1 Q8TE77;C9JUG3;Q8TE77-4;Q8TE77-2 Q8TE77 SSH3 Protein phosphatase Slingshot homolog 3 1 ALVT(0.504)VS(0.14)RS(0.14)PPGS(0.14)GAS(0.055)T(0.021)PVGPWDQAVQR;ALVT(0.355)VS(0.182)RS(0.182)PPGS(0.182)GAS(0.044)T(0.055)PVGPWDQAVQR 66.017 1.7613999999999997e-10 22916000.0 2495.7 6294.0 5955.700000000001 4847.0 4831.0 4087.6000000000004 7115.9 7066.5 6107.6 4173.9 True False 2460.1108603446723 6279.426629702209 5466.045335666831 5203.464549118004 4546.850078111435 3912.7828766609973 7484.326483633889 7394.835387526551 5419.697772120753 4895.35305362784 0.5025400279396677 1.2827321259390396 1.116578370505078 1.0629395861983495 0.928809429739059 0.799285124851479 1.5288634755541108 1.5105826498144803 1.1071107053462328 1.0 12.257197195635175 -7.2591673482240555 24.993826066884427 1.3291877606909972 0.9758960695592976 0.30085728376614884 0.24687007586737342 247.19063479006653 2719274.226937571 0.09636583589964816 0.07100561666284654 5.505954926208144e-08 7.2591673482240555 -0.35329169113169956 (ac)ALVTVSRS(ph)PPGSGASTPVGPWDQAVQR ddPTM_PC-9_AZD4547_30min_R2 1 ALVTVSRSPPGSGASTPVGPWDQAVQR 27 1 Q8TE77;C9JUG3;Q8TE77-4;Q8TE77-2 Q8TE77 SSH3 Protein phosphatase Slingshot homolog 3 1 ALVT(0.225)VS(0.225)RS(0.49)PPGS(0.03)GAS(0.019)T(0.011)PVGPWDQAVQR 53.876000000000005 1.5597e-07 0.0 0.0 0.0 966.71 1655.1 1915.0 0.0 989.71 0.0 1623.7 925.36 True False 0.0 0.0 953.8907937629066 1273.5422660400945 1649.1353053061382 0.0 1077.7922726776794 0.0 1709.525467150751 892.9634280576634 0.0 0.0 1.0682305274671438 1.4261975642275186 1.8468116985409675 0.0 1.206983666757829 0.0 1.9144406292979312 1.0 9.802457279745763 -5.260186196977154 24.999987386518235 1.030999488720859 6.205799440492936e-05 0.32178626938760146 0.6133055355142615 126.27347448399607 2518984.3979925294 0.15544852746981808 0.3675433987404056 5.4930531728882165e-06 5.260186196977154 -1.030937430726454 (ac)AMS(ph)SGGSGGGVPEQEDSVLFR ddPTM_PC-9_AZD4547_30min_R2 1 AMSSGGSGGGVPEQEDSVLFR 21 0 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 1 AMS(0.5)S(0.5)GGSGGGVPEQEDSVLFR 137.46 4.0551999999999993e-109 0.0 0.0 686.48 673.07 880.21 543.02 654.15 569.19 996.81 0.0 597.82 True False 0.0 908.3712351519318 664.1446520238746 677.2911836089366 467.6310462074883 613.2458970900205 619.8468073328636 842.7759189150444 0.0 576.8905037622461 0.0 1.574599043020994 1.1512490631975953 1.1740376712598284 0.8106062470395822 1.063019573195744 1.0744617969796242 1.4608940750780284 0.0 1.0 9.172153705058118 -8.255269571666304 24.998348148887608 0.5000000021402902 1.059152516735534 0.17767664062287702 0.4617998164544171 707.8250738567441 2867939.937819063 0.3073129471674152 0.10959960127841138 5.555593080617357e-09 8.255269571666304 0.5591525145952438 (ac)AMS(ph)SGGSGGGVPEQEDSVLFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AMSSGGSGGGVPEQEDSVLFR 21 0 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 1 AMS(0.445)S(0.445)GGS(0.109)GGGVPEQEDSVLFR 80.507 5.3228e-06 1788400.0 0.0 584.57 451.12 0.0 0.0 0.0 0.0 0.0 507.83 0.0 True False 0.0 642.6022463114588 461.87641168212707 0.0 0.0 0.0 0.0 0.0 515.2560530300284 0.0 0.0 (ac)AMS(ph)SGGSGGGVPEQEDSVLFR ddPTM_PC-9_Lapatinib_30min_R1 1 AMSSGGSGGGVPEQEDSVLFR 21 0 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 1 AMS(0.993)S(0.007)GGSGGGVPEQEDSVLFR 128.73 4.666999999999999e-12 882380.0 0.0 856.19 886.63 581.94 1099.6 590.03 916.46 479.32 581.04 475.92 True False 0.0 854.2075446591564 813.7347038907744 624.7378088949318 1034.923689896778 564.7957923271086 963.9098145267806 501.590957043689 515.5971565775494 558.1821378764618 0.0 1.5303383728990119 1.457830067774172 1.1192364758780589 1.8540967538553335 1.0118485598192155 1.7268732714985506 0.8986152064126107 0.9237077319225551 1.0 9.124592147913273 -4.755252691206296 24.99350968066612 1.3011293881256767 2.1378309605613823e-06 0.5775840365858486 0.3280297531637979 143.98557498901272 581629.2657085422 0.079345463857415 0.7163205673199238 1.756901075908182e-05 4.755252691206296 -1.3011272502947162 (ac)AMSS(ph)GGSGGGVPEQEDSVLFR ddPTM_PC-9_Lapatinib_30min_R1 1 AMSSGGSGGGVPEQEDSVLFR 21 0 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 1 AMS(0.239)S(0.748)GGS(0.013)GGGVPEQEDSVLFR 67.648 6.1003999999999994e-05 908610.0 1962.7 370.82 937.02 704.2 967.3 776.17 800.19 669.14 921.98 795.16 True False 1934.7115380849025 369.96138907311297 859.9818326017988 755.9892171423353 910.4053157849705 742.9750184406419 841.6199228402596 700.2306872156682 818.136903520186 932.6023465159008 2.0745299916012123 0.3966978964349037 0.9221313197576607 0.8106233272590696 0.9761988259906745 0.7966686136018362 0.9024424246673393 0.7508352191388459 0.877262325766877 1.0 9.865118249414568 -4.748951673415649 24.999957589223825 0.8267962537657995 2.0745328838332915 0.8428644137937671 0.1617414884755224 208.30672143299054 416997.7981415418 0.037787692397490025 0.6539223188877414 1.7825771145928736e-05 4.748951673415649 1.2477366300674921 (ac)ANYIHVPPGS(ph)PEVPK ddPTM_PC-9_AZD4547_30min_R2 1 ANYIHVPPGSPEVPK 15 0 H0YFP7;Q86U68;H0YH69;A0A5K1VW28 H0YFP7 ETNK1 1 ANY(0.097)IHVPPGS(0.903)PEVPK 48.823 0.0074994 0.0 6186.0 5369.4 6749.2 8153.6 7652.6 7239.9 6997.2 7740.3 6580.3 7164.6 True False 8153.019323206789 7104.953545660151 6659.701198151064 6273.913491864248 6590.168583491259 6787.1879084950515 7619.9372446274665 6544.214489399302 6928.121224051294 6913.769534734514 1.1792437225809063 1.027652644474933 0.9632518360198412 0.9074519276849403 0.953194715326061 0.9816913731932311 1.1021393186951334 0.9465479658414152 1.0020758125136624 1.0 12.755256797918571 -4.784260084546287 2.9369980479344466 0.9810837214036469 1.2122668149241316 0.6008843797832445 0.04820770740274093 0.28608958722912825 3.530539125611266 0.013196257580409357 0.15862047893959447 1.6433872583954274e-05 4.784260084546287 0.23118309352048472 (ac)ANYIHVPPGS(ph)PEVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ANYIHVPPGSPEVPK 15 0 H0YFP7;Q86U68;H0YH69;A0A5K1VW28 H0YFP7 ETNK1 1 ANYIHVPPGS(1)PEVPK 79.652 0.0021184999999999997 0.0 5173.9 6636.5 6330.4 7023.0 5887.7 7382.2 8034.2 6606.2 6608.1 6416.6 True False 6049.739080816967 7295.3278608994615 6481.340744175692 6629.5240788732035 4734.047450208089 6995.064436379627 7273.142413429121 6432.794249847486 6704.730961203026 7579.878786222347 0.7981313753741476 0.9624596997724947 0.8550718193484274 0.8746213845692933 0.6245545059128101 0.9228464773202292 0.9595328129322108 0.8486671662270019 0.8845432955194423 1.0 12.887959062357378 (ac)ANYIHVPPGS(ph)PEVPK ddPTM_PC-9_Lapatinib_30min_R1 1 ANYIHVPPGSPEVPK 15 0 H0YFP7;Q86U68;H0YH69;A0A5K1VW28 H0YFP7 ETNK1 1 ANY(0.162)IHVPPGS(0.838)PEVPK 53.008 0.007602500000000001 0.0 7420.3 6185.3 10112.0 7347.0 9171.9 8941.0 5971.4 5402.7 8598.4 5425.0 True False 7314.485161283642 6170.978317873698 9280.630393448795 7887.322888873531 8632.426874649196 8558.61427248898 6280.569873715401 5653.729165526035 7629.957646833955 6362.704021641882 1.1495875238584734 0.9698672603477932 1.4585984766668352 1.2396180715063696 1.3567229978460662 1.3451221750026412 0.9870913140628398 0.8885733402489941 1.1991690358189977 1.0 12.635424296957197 -7.271718785663133 24.5247230564901 1.0094228447689622 1.253788923744306 0.39257035623268466 0.1427410660486933 594.4196583040741 1418166.508829478 0.06157038489517631 0.04205940334176258 5.3491061256971686e-08 7.271718785663133 0.2443660789753439 (ac)AQES(ph)PKNSAAEIPVTSNGEVDDSR ddPTM_PC-9_AZD4547_30min_R2 2 AQESPKNSAAEIPVTSNGEVDDSR 24 1 P53367;P53367-2;P53367-3 P53367 ARFIP1 Arfaptin-1 1 AQES(0.71)PKNS(0.29)AAEIPVTSNGEVDDSR;AQES(0.756)PKNS(0.242)AAEIPVT(0.002)SNGEVDDSR 56.681000000000004 2.7101999999999995e-07 8846800.0 2475.3 2962.1000000000004 5800.700000000001 6265.0 4392.2 9278.3 5945.6 3541.2999999999997 4294.1 2060.5 True False 3262.3939105615505 3919.5408979774197 5723.778927889949 4820.701043285116 3782.4188448906657 8698.126434258715 6474.746881846613 2994.073455978417 4521.077359421102 1988.3625221673897 1.6407440163403497 1.971240583284065 2.878639515721115 2.4244578086446587 1.902278283120971 4.3745173917165925 3.2563211233678335 1.5057985767679651 2.2737691487430363 1.0 10.957365100542265 (ac)AQES(ph)PKNSAAEIPVTSNGEVDDSREHSFNR ddPTM_PC-9_AZD4547_30min_R2 3 AQESPKNSAAEIPVTSNGEVDDSREHSFNR 30 2 P53367;P53367-2;P53367-3 P53367 ARFIP1 Arfaptin-1 1 AQES(0.933)PKNS(0.066)AAEIPVTSNGEVDDSREHSFNR;AQES(0.825)PKNS(0.175)AAEIPVTSNGEVDDSREHSFNR;AQES(0.876)PKNS(0.099)AAEIPVT(0.017)S(0.007)NGEVDDSREHSFNR 72.122 3.6337e-17 31412400.0 4619.7 4391.139999999999 10454.900000000001 22645.2 16714.199999999997 9782.1 11630.3 6952.1900000000005 6969.9 11577.2 True False 6088.668504270674 5810.490131577108 10316.26119488969 17424.699004852366 14393.721838092873 9170.423740616512 12665.374169123485 5877.888780933159 7338.314684667138 11171.885751825423 0.5449991737765327 0.5200993154291528 0.9234127007791922 1.5596918364480472 1.2883878476595612 0.8208483280558179 1.1336827506541618 0.5261321957193078 0.6568555074480689 1.0 13.447585104778547 -11.487473173638548 4.459922335233832 1.0675836351030092 0.9027818804336855 0.008132949560714309 0.33428667017391317 0.2864817932851108 0.002274266045006107 0.41277433298502825 0.08707686533864335 3.2548188788681347e-12 11.487473173638548 -0.16480175466932379 (ac)AQES(ph)PKNSAAEIPVTSNGEVDDSREHSFNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQESPKNSAAEIPVTSNGEVDDSREHSFNR 30 2 P53367;P53367-2;P53367-3 P53367 ARFIP1 Arfaptin-1 1 AQES(0.773)PKNS(0.227)AAEIPVTSNGEVDDSREHSFNR 58.812 3.7139e-12 9123100.0 0.0 0.0 0.0 6001.0 5834.0 4485.4 5648.6 4775.2 2061.8 2372.8 True False 0.0 0.0 0.0 5664.783425504501 4690.869579719415 4250.177727904577 5113.523715677449 4649.856059742622 2091.9499244576205 2802.969856925536 0.0 0.0 0.0 2.020993344437165 1.673535506680275 1.516312320449434 1.82432347713017 1.6589033407740106 0.746333364694901 1.0 11.452740514406067 -5.750257616733516 24.995865960432152 1.5414282629431117 2.557215661993608e-07 0.785988955714719 0.355979943941058 90.51188558075238 202329.6581246839 0.09593868647792368 0.16423076764467748 1.7772248751423714e-06 5.750257616733516 -1.5414280072215456 (ac)AQESPKNS(ph)AAEIPVTSNGEVDDSREHSFNR ddPTM_PC-9_Lapatinib_30min_R1 1 AQESPKNSAAEIPVTSNGEVDDSREHSFNR 30 2 P53367;P53367-2;P53367-3 P53367 ARFIP1 Arfaptin-1 1 AQES(0.45)PKNS(0.547)AAEIPVT(0.002)SNGEVDDSREHSFNR 41.475 3.1853e-05 7196600.0 2934.2 1083.3 1115.7 1461.6 1274.0 3412.2 1029.5 1012.5 1459.2 780.91 True False 2892.3577699336224 1080.7916854077541 1023.9714527265447 1569.090939754669 1199.0658247803703 3266.2681602266966 1082.8024726178126 1059.5444463129752 1294.8495299427925 915.8892530028322 3.1579776271538784 1.1800462576280628 1.1180079353146186 1.7131885046256974 1.3091821100085148 3.566226101592434 1.1822417056076802 1.1568477769983165 1.413762117742404 1.0 9.839029351630831 -10.815758050593706 0.1411938192588072 3.139461647380359e-06 2.172523901828705 0.11593500002499102 0.8143538616000181 94.87357618407162 2.469171843354244 38.97978785617248 6.7937350159026275 1.5284173162839337e-11 10.815758050593706 2.1725207623670575 (ac)AQRHS(ph)DSSLEEK ddPTM_PC-9_Lapatinib_30min_R1 1 AQRHSDSSLEEK 12 1 Q5VV41 Q5VV41 ARHGEF16 Rho guanine nucleotide exchange factor 16 1 AQRHS(0.732)DS(0.219)S(0.048)LEEK 50.207 0.0054506 20604000.0 76600.0 54166.0 68375.0 56588.0 80998.0 82518.0 65631.0 57618.0 95288.0 57682.0 True False 75507.66995328043 54040.581954949106 62753.47143513263 60749.670292034185 76233.85688819496 78988.89749885311 69029.05204505064 60295.14262485036 84555.66201287601 67652.2568435663 1.116114575865198 0.7987993967430865 0.9275887363261033 0.8979696040666743 1.1268486883515516 1.1675722464292768 1.0203510609360444 0.8912510156796699 1.249857225138783 1.0 16.04585044209882 -6.254748968756894 24.611233754910224 1.0723407521254122 0.92484321311076 0.25524693739882043 0.11725330306139631 601.4647942207728 2212534.998490475 0.034373653261735866 0.043363340171306795 5.562256743768802e-07 6.254748968756894 -0.14749753901465223 (ac)AQS(ph)SPQLDIQVLHDLR ddPTM_PC-9_AZD4547_30min_R2 2 AQSSPQLDIQVLHDLR 16 0 F6SS63;Q8N5C8-2;Q8N5C8;A0A0A0MQY2 F6SS63 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 1 AQS(0.5)S(0.5)PQLDIQVLHDLR;AQS(0.5)S(0.5)PQLDIQVLHDLR 84.506 0.0079682 1354600.0 0.0 776.6 1305.41 2406.85 1472.58 1413.6 505.89 1297.2 682.57 523.95 True False 0.0 1027.6207627592798 1288.099410460259 1851.9879179618165 1268.1376855810513 1325.207368533903 550.9132299612119 1096.7475466905385 718.6492567057273 505.606669977968 0.0 2.032450961938573 2.54763136434966 3.6629024653541804 2.50815062553726 2.6210243005529366 1.089608311506686 2.169171436639334 1.421360316977311 1.0 8.981871685490423 -7.256163993078028 24.83674588667832 1.5174659713316057 2.3121642963199664 0.15181119758494666 0.9122980138649242 855.3861053181615 4027206.6751056802 0.3759250729682833 0.2823592998486314 5.544163213788204e-08 7.256163993078028 0.7946983249883608 (ac)AQS(ph)SPQLDIQVLHDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQSSPQLDIQVLHDLR 16 0 F6SS63;Q8N5C8-2;Q8N5C8;A0A0A0MQY2 F6SS63 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 1 AQS(0.5)S(0.5)PQLDIQVLHDLR 64.65 0.025481999999999998 996210.0 503.73 399.05 0.0 0.0 0.0 676.07 0.0 0.0 0.0 0.0 True False 589.0015398789942 438.66504677042536 0.0 0.0 0.0 640.6156990467845 0.0 0.0 0.0 0.0 0.0 (ac)AQS(ph)SPQLDIQVLHDLR ddPTM_PC-9_Lapatinib_30min_R1 2 AQSSPQLDIQVLHDLR 16 0 F6SS63;Q8N5C8-2;Q8N5C8;A0A0A0MQY2 F6SS63 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 1 AQS(0.5)S(0.5)PQLDIQVLHDLR;AQS(0.5)S(0.5)PQLDIQVLHDLR 106.19 0.012145999999999999 1070400.0 1092.6 2633.0 2616.4 1573.3600000000001 3258.77 2043.5 1131.2 750.94 2457.0 1901.6599999999999 True False 1077.0193236416992 2626.9034502710365 2401.289691596069 1689.0701429751005 3067.0955555883256 1956.1042686311644 1189.7680009958904 785.8314138412499 2180.2667866429824 2230.359397197327 0.4828904816842897 1.1777937912481762 1.076638004894428 0.757308506018173 1.3751575461077898 0.8770354549536761 0.5334422795227328 0.352333984750945 0.9775405656069193 1.0 11.123060487532689 -7.010264843417098 24.67564108943842 0.668054396228847 0.9936648937507716 0.1423884410313293 0.28754979516627693 643.5898898443501 1547125.1518503607 0.10233391011982823 0.08487399367381943 9.766414594255201e-08 7.010264843417098 0.3256104975219246 (ac)AQSS(ph)PQLDIQVLHDLR ddPTM_PC-9_AZD4547_30min_R2 1 AQSSPQLDIQVLHDLR 16 0 F6SS63;Q8N5C8-2;Q8N5C8;A0A0A0MQY2 F6SS63 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 1 AQS(0.221)S(0.779)PQLDIQVLHDLR 109.35 8.9916e-06 1451100.0 0.0 0.0 0.0 695.58 569.39 0.0 446.65 610.34 0.0 745.81 True False 0.0 0.0 0.0 535.2247776038724 490.34002688682125 0.0 486.4009847242983 516.0259772179332 0.0 719.6994189068967 0.0 0.0 0.0 0.7436782127972114 0.6813122450919384 0.0 0.6758390682919548 0.7170020756744401 0.0 1.0 9.491250683280102 -5.745374635073958 24.51589956826041 0.5219853174178211 3.755350023267136e-07 0.4056421222748682 0.3016074990491899 198.2429791540595 302529.1008889592 0.07990890386701784 0.13781213939297432 1.7973198257680231e-06 5.745374635073958 -0.5219849418828187 (ac)AQSS(ph)PQLDIQVLHDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AQSSPQLDIQVLHDLR 16 0 F6SS63;Q8N5C8-2;Q8N5C8;A0A0A0MQY2 F6SS63 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 1 AQS(0.112)S(0.888)PQLDIQVLHDLR;AQS(0.094)S(0.906)PQLDIQVLHDLR 76.15100000000001 0.0051034 2066250.0 832.04 604.81 990.02 2184.6 2225.4 2171.9 2075.6 967.91 1541.31 1987.3 True False 972.8879384609191 664.8515397499585 1013.6258314717578 2062.2039445687597 1789.3488451675669 2058.001740588566 1878.9841419573174 942.5033880854161 1563.8487428779574 2347.5817585418554 0.41442132310024654 0.28320697983396975 0.43177445376869317 0.8784375398493677 0.7622093836165171 0.8766475259489344 0.8003913538348516 0.40147840843286736 0.6661530475723686 1.0 11.19695968773343 -5.645265291995988 5.514440351103566 0.7489187039360674 0.3518438680875195 0.578510326927275 0.15376024978023248 0.15730026972043956 6.931908006767552 0.044321326230783484 0.07781943278825103 2.2632613553064714e-06 5.645265291995988 -0.3970748358485479 (ac)ARGS(ph)VSDEEMMELR ddPTM_PC-9_AZD4547_30min_R2 1 ARGSVSDEEMMELR 14 1 P13796;Q5TBN3;Q5TBN5 P13796 LCP1 Plastin-2 1 ARGS(0.984)VS(0.016)DEEMMELR 88.22399999999999 3.6352999999999997e-06 17352000.0 3084.6 2350.0 6367.3 10447.0 7946.7 5634.3 2740.8 7259.0 8822.1 8837.8 True False 4065.438636334244 3109.591543245311 6282.865441680084 8038.605554541034 6843.4378750267815 5281.986330313081 2984.725890366856 6137.2883452255755 9288.418195325894 8528.391312016956 0.47669466463221793 0.3646164240685968 0.7366999486558728 0.9425699713396373 0.8024300978525709 0.6193414604311698 0.3499752510372289 0.7196302468647059 1.0891172620372167 1.0 13.058057920103746 -7.147350861892942 0.08258678223820079 1.4292949299013114 8.852085532612609e-17 0.3104257037721765 0.20388550154497276 39.59276125381897 1.819719631158967 12.880451169189838 17.32072285301284 7.122773563167935e-08 7.147350861892942 -1.4292949299013114 (ac)ARGS(ph)VSDEEMMELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ARGSVSDEEMMELR 14 1 P13796;Q5TBN3;Q5TBN5 P13796 LCP1 Plastin-2 1 ARGS(0.923)VS(0.077)DEEMMELR 63.727 0.00014564 12773000.0 1893.7 1723.1 2012.3 1743.8 1352.6 2246.3 2094.7 2675.9 0.0 1710.4 True False 2214.2660077201126 1894.157980428818 2060.2808636902478 1646.100539475879 1087.5677397203428 2128.5000736148504 1896.2748516852937 2605.6604603504093 0.0 2020.4819804810495 1.0959098022705087 0.9374782842546533 1.0196977174722057 0.8147068646877834 0.5382714373237854 1.0534615473819189 0.9385259903351458 1.2896232114527626 0.0 1.0 10.980483769671926 -5.761983881066433 24.702647703276355 0.8218187071116486 1.0096736001235551 0.07874693291949653 0.3296139529824804 38.001106301775074 1724205.6855070556 0.08866789160369065 0.1410745722759898 1.729880562914627e-06 5.761983881066433 0.1878548930119065 (ac)ARGS(ph)VSDEEMMELR ddPTM_PC-9_Lapatinib_30min_R1 2 ARGSVSDEEMMELR 14 1 P13796;Q5TBN3;Q5TBN5 P13796 LCP1 Plastin-2 1 ARGS(0.956)VS(0.044)DEEMMELR;ARGS(0.654)VS(0.346)DEEMMELR 106.55 3.4073999999999997e-15 11854000.0 10449.7 8170.900000000001 7480.8 5710.4 5362.0 8277.3 5119.4 5397.3 5057.0 1415.5 True False 10300.685361759712 8151.980783068597 6865.757500723082 6130.361865335971 5046.617702097602 7923.299174328722 5384.457482583421 5648.078261812367 4487.427407429207 1660.1672889648084 6.20460686716859 4.9103369505320975 4.1355817250225435 3.692616946547921 3.0398248029838024 4.7725908268372566 3.2433222352796025 3.402113931141365 2.702997123999068 1.0 10.69711290864374 -1.522878745280544 0.09877807080002278 1.0648756123898255e-12 16.03694979455501 0.7912251639855348 0.6146240214871262 66.24505968879284 0.46637703023330057 8.774213459133096 143.90989630724064 0.029999999999985746 1.522878745280544 16.036949794553944 (ac)ARGSVS(ph)DEEMMELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ARGSVSDEEMMELR 14 1 P13796;Q5TBN3;Q5TBN5 P13796 LCP1 Plastin-2 1 ARGS(0.271)VS(0.729)DEEMMELR 60.345 0.00099883 14381000.0 11633.0 6670.1 8008.4 8989.9 11235.0 9378.2 11485.0 8381.1 10677.0 9006.6 True False 13602.237137776874 7332.263446844795 8199.350628026128 8486.22504864904 9033.582401122327 8886.390682622441 10397.05765580064 8161.105005509481 10833.130926100497 10639.425283793627 1.2784748024403454 0.6891597291456687 0.7706572873363459 0.7976206253899425 0.8490667644315919 0.835232209032806 0.9772198571324927 0.7670625797749417 1.018206400922983 1.0 13.377132601571397 -8.285090487940774 23.595982038110908 1.009103357525827 0.8604146007151019 0.11098785043654524 0.1547219326014158 911.0622141578439 908921.6783314379 0.14139316991633505 0.03662086472414776 5.1869195499320765e-09 8.285090487940774 -0.14868875681072513 (ac)ARGSVS(ph)DEEMMELR ddPTM_PC-9_Lapatinib_30min_R1 2 ARGSVSDEEMMELR 14 1 P13796;Q5TBN3;Q5TBN5 P13796 LCP1 Plastin-2 1 ARGS(0.121)VS(0.879)DEEMMELR;ARGS(0.418)VS(0.582)DEEMMELR 120.29 2.9242e-20 13241000.0 6761.1 4488.0 5485.5 7085.0 3115.2 3713.0 1164.0 3555.41 3982.3 2555.63 True False 6664.685474166112 4477.608311741899 5034.503364642346 7606.054534867151 2931.9700607188443 3554.2036454257454 1224.2662245042577 3720.6073282623333 3533.7714385219165 2997.367240337079 2.2235131499657723 1.4938470840291012 1.679641819290777 2.537578456356181 0.978181792761944 1.185775168819836 0.40844718926286083 1.2412917837334874 1.1789584509252575 1.0 11.54948013973647 -6.288254917217567 24.495431668417314 0.9906737012848904 1.9269450069185905 0.6613748886183216 0.34425493220399866 369.13819147444144 337198.851637218 0.10763095158002618 0.12207873344483235 5.149263102922798e-07 6.288254917217567 0.9362713056337001 (ac)AS(ph)AVSPANLPAVLLQPR ddPTM_PC-9_AZD4547_30min_R2 4 ASAVSPANLPAVLLQPR 17 0 P51610;A6NEM2;P51610-2;P51610-4;P51610-3 P51610 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 AS(0.528)AVS(0.472)PANLPAVLLQPR;AS(0.5)AVS(0.5)PANLPAVLLQPR;AS(0.996)AVS(0.004)PANLPAVLLQPR;AS(0.674)AVS(0.326)PANLPAVLLQPR 141.1 2.0164999999999997e-57 32924000.0 0.0 0.0 0.0 0.0 802.24 769.58 553.51 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 690.8628236703896 721.4580409425018 602.7713177090479 0.0 0.0 0.0 0.0 (ac)AS(ph)AVSPANLPAVLLQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASAVSPANLPAVLLQPR 17 0 P51610;A6NEM2;P51610-2;P51610-4;P51610-3 P51610 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 AS(0.604)AVS(0.396)PANLPAVLLQPR;AS(0.5)AVS(0.5)PANLPAVLLQPR 121.61 4.745499999999999e-22 13212200.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)AS(ph)AVSPANLPAVLLQPR ddPTM_PC-9_Lapatinib_30min_R1 3 ASAVSPANLPAVLLQPR 17 0 P51610;A6NEM2;P51610-2;P51610-4;P51610-3 P51610 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 AS(0.5)AVS(0.5)PANLPAVLLQPR;AS(0.979)AVS(0.021)PANLPAVLLQPR;AS(0.525)AVS(0.475)PANLPAVLLQPR 101.3 9.396599999999999e-06 32914400.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)AS(ph)CASIDIEDATQHLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASCASIDIEDATQHLR 16 0 Q6P2E9 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 AS(0.501)CAS(0.499)IDIEDATQHLR 105.2 1.3627e-11 2462900.0 597.58 617.77 539.63 516.36 432.5 978.54 610.08 453.77 0.0 611.72 True False 698.7384912570022 679.0981229003024 552.4968257581712 487.43002326170694 347.754729727228 927.2236397787809 552.2888058032962 441.8590183090569 0.0 722.6199936271447 0.9669515062124551 0.9397721193564171 0.7645745075291217 0.6745316038310581 0.4812415000887194 1.283141413130076 0.7642866384461879 0.6114680222051067 0.0 1.0 9.497093361937395 -7.85263910631778 3.7899172072935574 0.44982545779219596 0.8383727953692368 0.174586172224534 0.29992757169940776 0.33688470659918807 9.132293045567378 0.1751062666863217 0.0787460267334994 1.403979910980716e-08 7.85263910631778 0.38854733757704085 (ac)AS(ph)EDNRVPSPPPTGDDGGGGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASEDNRVPSPPPTGDDGGGGGR 22 1 E9PEM5;A0A494C1L5;P50851-2;P50851;A0A494C0R9 E9PEM5 LRBA Lipopolysaccharide-responsive and beige-like anchor protein 1 AS(0.498)EDNRVPS(0.498)PPPT(0.004)GDDGGGGGR 83.869 0.00033906 18997000.0 0.0 0.0 1003.5 988.4 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 1027.4272457949428 933.0231524360358 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)AS(ph)EELQKDLEEVK ddPTM_PC-9_AZD4547_30min_R2 1 ASEELQKDLEEVK 13 1 Q9HB71;B2ZWH1;Q9HB71-2 Q9HB71 CACYBP Calcyclin-binding protein 1 AS(1)EELQKDLEEVK 74.84100000000001 0.0028155999999999997 1586400.0 8797.0 7715.3 8595.9 11247.0 9727.3 7750.1 9037.7 7597.4 7215.3 7265.5 True False 11594.263011032997 10209.119844085328 8481.912749538711 8654.177914417827 8376.832300420056 7265.48502184112 9842.037791655193 6423.3964008839785 7596.686027673104 7011.137056446087 1.653692249586414 1.4561289790646716 1.209777056310771 1.2343472741644834 1.1947894090471871 1.0362777055058685 1.4037719862581144 0.9161704227388144 1.0835169768488064 1.0 12.77543272214589 -1.5228787452805221 0.410533020810345 1.0685680278788527 11.43933554808438 0.6960331990686821 0.11973482594777257 42.49655648759886 0.5539113292224627 0.08236564918172458 359.38910490349093 0.02999999999998725 1.5228787452805221 10.370767520205527 (ac)AS(ph)ESDTEEFYDAPEDVHLGGGYPVGSPGK ddPTM_PC-9_AZD4547_30min_R2 1 ASESDTEEFYDAPEDVHLGGGYPVGSPGK 29 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 AS(0.684)ES(0.142)DT(0.157)EEFY(0.018)DAPEDVHLGGGYPVGSPGK 59.661 0.0011658 0.0 3769.4 7229.0 7045.1 10657.0 6830.7 6076.7 4570.4 7181.5 6201.2 6171.3 True False 4967.990791609385 9565.632879200144 6951.677370813433 8200.193299008693 5882.375211464567 5696.72298837717 4977.156745962015 6071.764189452748 6528.982771999288 5955.24466539753 0.8342211060572365 1.6062535490406438 1.167320196129908 1.3769700087479624 0.9877638186124634 0.9565892433399957 0.8357602459024703 1.0195658668286536 1.0963416515756972 1.0 12.53994506568258 -6.2794445631447555 21.82182321263396 0.9749987298918872 1.2662762532805316 0.3129797319958151 0.19013843530354566 168.47176876108503 204182.31776503584 0.055817675100746936 0.06350150262029418 5.254790872238945e-07 6.2794445631447555 0.29127752338864443 (ac)AS(ph)GEHSPGSGAAR ddPTM_PC-9_AZD4547_30min_R2 1 ASGEHSPGSGAAR 13 0 A6NKB8;Q9H4A4 A6NKB8 RNPEP Aminopeptidase B 1 AS(0.604)GEHS(0.384)PGS(0.011)GAAR 74.78 0.00011562 2662200.0 2367.7 1305.1 2630.3 2956.2 2901.0 3353.8 2478.0 2632.4 2374.8 3823.0 True False 3120.579348780586 1726.94805237849 2595.42050339251 2274.6937628347087 2498.2462249050177 3144.0863558213086 2698.537199477917 2225.6230665342086 2500.3270797497107 3689.157933630638 0.8458784917645169 0.46811442704458467 0.7035265364305668 0.6165888811911334 0.6771860326528228 0.8522504084630218 0.7314778190648471 0.6032875541177739 0.6777500786714884 1.0 11.849075837096414 -6.538311943306392 24.804756582863337 0.7476944293067391 0.6479837882100735 0.13406435701340702 0.13273451994991975 493.11466719167356 792544.9495208343 0.04229957737346145 0.04231354944836065 2.895263242538233e-07 6.538311943306392 -0.09971064109666561 (ac)AS(ph)GVAVSDGVIK ddPTM_PC-9_AZD4547_30min_R2 21 ASGVAVSDGVIK 12 0 P23528;E9PP50;E9PS23 P23528 CFL1 Cofilin-1 1 AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(0.997)GVAVS(0.003)DGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(0.999)GVAVS(0.001)DGVIK;AS(0.982)GVAVS(0.018)DGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(0.985)GVAVS(0.015)DGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(0.996)GVAVS(0.004)DGVIK 111.06 2.5265000000000003e-07 4564702070.0 10239475.700000001 11990104.000000002 13710156.400000002 21795818.5 17861134.8 18103392.200000003 13257996.099999998 16168990.900000002 14551445.200000001 16022020.6 True False 13495415.978274517 15865670.638736915 13528350.768078957 16771129.286863994 15381424.538648652 16971384.22389588 14437932.068758348 13670444.882852815 15320604.885907855 15461094.535517551 0.8728629106608568 1.0261673649488374 0.874993082604944 1.0847310485255106 0.9948470661837117 1.0976832322516923 0.9338234130572857 0.8841835131043784 0.9909133438588736 1.0 23.882139119636527 -4.748003314708394 24.546670254806077 0.9853839834037988 0.8728625630173149 0.1920870571799249 0.0704018331592013 968.8292118355777 1769846.2060245678 0.017797394657507966 0.3328428498414811 1.7864739397196485e-05 4.748003314708394 -0.11252142038648394 (ac)AS(ph)GVAVSDGVIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 27 ASGVAVSDGVIK 12 0 P23528;E9PP50;E9PS23 P23528 CFL1 Cofilin-1 1 AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(0.999)GVAVS(0.001)DGVIK;AS(1)GVAVSDGVIK;AS(0.999)GVAVS(0.001)DGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(0.999)GVAVS(0.001)DGVIK;AS(1)GVAVSDGVIK;AS(0.999)GVAVS(0.001)DGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(0.998)GVAVS(0.002)DGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(0.998)GVAVS(0.002)DGVIK;AS(0.999)GVAVS(0.001)DGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(0.999)GVAVS(0.001)DGVIK;AS(0.996)GVAVS(0.004)DGVIK 128.27 3.7104e-08 5326631700.0 8270065.800000001 7659348.5 8180496.4 8979592.3 10090526.5 7675855.7 8470654.7 6403700.7 7382568.399999999 7064889.2 True False 9670024.598694947 8419718.000209229 8375550.458881355 8476494.855662024 8113360.267775544 7273320.314520318 7668252.964586733 6235610.3419067385 7490524.496402756 8345697.686327863 1.1586837868015074 1.0088692781195068 1.0035770253938623 1.0156724068196763 0.972160815394387 0.8715053657449945 0.9188270714800828 0.7471646561224086 0.8975312523809635 1.0 22.9926012308391 -5.87635146017705 0.6683460339647272 0.8660787142582382 1.120561995513837 0.5491053409542868 0.06956741745673024 0.7868719703861102 0.6330783609183074 0.03961370627646468 0.12608896523088745 1.3293781607183673e-06 5.87635146017705 0.2544832812555988 (ac)AS(ph)GVAVSDGVIK ddPTM_PC-9_Lapatinib_30min_R1 26 ASGVAVSDGVIK 12 0 P23528;E9PP50;E9PS23 P23528 CFL1 Cofilin-1 1 AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(0.999)GVAVS(0.001)DGVIK;AS(1)GVAVSDGVIK;AS(0.997)GVAVS(0.003)DGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(0.999)GVAVS(0.001)DGVIK;AS(1)GVAVSDGVIK;AS(0.999)GVAVS(0.001)DGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(0.998)GVAVS(0.002)DGVIK;AS(0.999)GVAVS(0.001)DGVIK;AS(0.999)GVAVS(0.001)DGVIK;AS(0.999)GVAVS(0.001)DGVIK;AS(0.998)GVAVS(0.002)DGVIK;AS(1)GVAVSDGVIK;AS(0.999)GVAVS(0.001)DGVIK;AS(1)GVAVSDGVIK 104.42 1.1414000000000001e-11 4665051630.0 12315817.2 10471514.999999998 11071060.5 9206677.700000001 10469268.899999999 11463603.199999997 9959295.400000002 7307408.300000001 12128909.700000001 6791788.900000001 True False 12140191.388283709 10447268.850385448 10160840.641219404 9883767.490634494 9853487.086676603 10973331.614100248 10474938.984605342 7646937.166623558 10762824.16650465 7965740.561875152 1.5240505630308756 1.3115251205126042 1.2755676088486014 1.2407845088426823 1.2369831794216848 1.377565780464874 1.3149987629197302 0.9599781849816424 1.3511391794526455 1.0 22.92537706230882 -1.5228787485509836 0.04360041650003502 0.38320168540659894 2.752335084869472 0.4379335570110857 0.12001919261487974 629.7349838933092 2.092463161554793 29.538323640573836 106.19482000168027 0.02999999977407178 1.5228787485509836 2.369133399462873 (ac)AS(ph)GVQVADEVCR ddPTM_PC-9_AZD4547_30min_R2 4 ASGVQVADEVCR 12 0 P60981;F6RFD5 P60981 DSTN Destrin 1 AS(1)GVQVADEVCR;AS(1)GVQVADEVCR;AS(1)GVQVADEVCR;AS(1)GVQVADEVCR 114.5 0.00022583 362041000.0 4610.9 5943.200000000001 15737.900000000001 19067.6 9044.9 18967.4 9220.8 17833.6 12020.4 9806.7 True False 6077.070287322041 7864.22317438958 15529.205163038818 14671.859411483356 7789.171761338642 17781.365479576936 10041.433336943492 15077.826895359523 12655.773803867025 9463.370417927168 0.6421676441841263 0.8310171563708206 1.6409803777331475 1.5503841404843837 0.8230864287614731 1.8789675025181694 1.06108425365251 1.593282966795474 1.3373431710854569 1.0 13.208138381464545 -5.118531473165609 5.152753862655753 1.375672177637763 0.6861932407492018 0.39935278359766235 0.3088032994694009 0.19087616440779934 7.105822525502025 0.07417051403901763 0.21156355187865958 7.611469769580563e-06 5.118531473165609 -0.6894789368885611 (ac)AS(ph)GVQVADEVCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASGVQVADEVCR 12 0 P60981;F6RFD5 P60981 DSTN Destrin 1 AS(1)GVQVADEVCR;AS(1)GVQVADEVCR;AS(1)GVQVADEVCR 86.898 0.0020283000000000002 366822900.0 1939.3 5329.1 6147.0 2336.3 9206.9 9208.7 4645.4 8276.6 6846.0 4951.3 True False 2267.5851870790584 5858.137829205046 6293.567792627315 2205.404685386798 7402.8740372846605 8725.779561010142 4205.354082216481 8059.348019782584 6946.109798640448 5848.931495530766 0.38769221161365036 1.0015740197472502 1.0760200897268672 0.3770611242535448 1.2656797302107707 1.4918587382460553 0.7189952704061997 1.3779180053554776 1.1875861093514342 1.0 12.513957376555359 -6.291698704781844 24.985930112915508 1.1857443206290403 0.7574739376525681 0.37774527101949806 0.28842581683582463 785.2886947687686 648431.5972266024 0.08854308854571526 0.10041012407277147 5.108592897222966e-07 6.291698704781844 -0.42827038297647224 (ac)AS(ph)GVQVADEVCR ddPTM_PC-9_Lapatinib_30min_R1 2 ASGVQVADEVCR 12 0 P60981;F6RFD5 P60981 DSTN Destrin 1 AS(1)GVQVADEVCR;AS(1)GVQVADEVCR 102.06 0.00048496 389870000.0 4691.6 1763.3 2553.1 4618.0 5031.5 2115.7 0.0 2392.6 2697.9 0.0 True False 4624.696923665932 1759.217187186828 2343.193973251001 4957.623125196402 4735.557062309604 2025.2164429375853 0.0 2503.7689306157263 2394.034091853523 0.0 0.0 (ac)AS(ph)GVTVNDEVIK ddPTM_PC-9_AZD4547_30min_R2 2 ASGVTVNDEVIK 12 0 Q9Y281;G3V2U0;F8WDN3 Q9Y281 CFL2 Cofilin-2 1 AS(0.899)GVT(0.101)VNDEVIK;AS(1)GVTVNDEVIK 123.86 0.0015349 52592000.0 79386.0 98477.0 95472.0 153028.0 152093.0 141685.0 96620.0 118294.0 102368.0 130196.0 True False 104629.09666862147 130307.76442730577 94205.97889970336 117749.75885903185 130977.5122662801 132825.41455201324 105218.99282225843 100014.38042569415 107778.96349158588 125637.87766857843 0.8327830635966627 1.0371694177375879 0.7498214761969346 0.9372154404712667 1.0425001973671282 1.0572083595871853 0.8374782730715716 0.7960527691300486 0.8578540603487208 1.0 16.938911952092987 -11.29578419838559 2.2433807015585217 1.0281729820879297 0.9088733842314259 0.06820306816817812 0.10422980095776664 13488930.264550325 8138926.123078913 2084188.6497756054 0.028853916529998448 5.0607606953428766e-12 11.29578419838559 -0.11929959785650379 (ac)AS(ph)GVTVNDEVIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASGVTVNDEVIK 12 0 Q9Y281;G3V2U0;F8WDN3 Q9Y281 CFL2 Cofilin-2 1 AS(0.926)GVT(0.074)VNDEVIK;AS(0.998)GVT(0.002)VNDEVIK 101.46 0.00012246 50316000.0 71731.0 58393.0 73338.0 67510.0 97102.0 74177.0 71662.0 51781.0 57650.0 56987.0 True False 83873.64154817085 64189.87113410713 75086.65605591386 63727.633570373015 78075.56015253933 70287.02753885447 64873.6565720492 50421.8036165046 58493.022186915216 67318.29199115616 1.2459264646701023 0.953527922879267 1.1153975217579533 0.9466614746961366 1.1597971048165687 1.044099983227268 0.9636854212012966 0.7490059852250661 0.8689023511559034 1.0 16.038710952427223 -7.442949751502039 3.2887902522235937 0.8560460028536473 1.0712639322382262 0.444802989886559 0.10204637760934337 0.21220374641996795 4.420067220805895 0.045719899689305586 0.027975438932010693 3.6062036490431534e-08 7.442949751502039 0.21521792938457895 (ac)AS(ph)GVTVNDEVIK ddPTM_PC-9_Lapatinib_30min_R1 2 ASGVTVNDEVIK 12 0 Q9Y281;G3V2U0;F8WDN3 Q9Y281 CFL2 Cofilin-2 1 AS(0.994)GVT(0.006)VNDEVIK;AS(1)GVTVNDEVIK 126.07 0.00069632 48516000.0 95946.0 72533.0 91075.0 71158.0 87296.0 82651.0 66779.0 57230.0 94813.0 53257.0 True False 94577.79244565872 72365.05429491424 83587.16505966651 76391.19669612934 82161.42091053945 79116.20939889127 70236.48986784345 59889.11472838672 84134.16151484793 62462.40148950817 1.5141555590292983 1.1585378174591865 1.338199669983977 1.2229948717063142 1.3153740322382599 1.2666213195818359 1.1244602863955062 0.9588026284651625 1.3469568813965627 1.0 15.930700417214073 -1.5228787456933384 0.10215720042228392 0.8945782024889684 2.324140072847775 0.3977047047063832 0.12446598224733463 129.39912345207958 0.9374439533048039 1.45198343568643 25.94528753188906 0.029999999971470917 1.5228787456933384 1.4295618703588064 (ac)AS(ph)HLRPPSPLLVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASHLRPPSPLLVR 13 1 Q8TDB6;Q8TDB6-2 Q8TDB6 DTX3L E3 ubiquitin-protein ligase DTX3L 1 AS(0.963)HLRPPS(0.037)PLLVR 49.28 0.0073918000000000005 5780800.0 2738.1 4357.9 3724.9 3930.0 4144.4 3396.4 3583.7 4152.5 4113.4 4173.4 True False 3201.606250059902 4790.5235116422455 3813.715742761914 3709.8148412319074 3332.3345708243305 3218.2868049795125 3244.2259922588364 4043.5012749374337 4173.550693211743 4930.004383383779 0.649412455057988 0.9717077590819911 0.7735724851717709 0.7524972703341944 0.6759293322447586 0.6527959317493741 0.6580574255051911 0.8201820851449464 0.8465612540383113 1.0 12.267373214000209 -8.516906651325987 1.6824076477977292 0.9961804215270722 0.7416415815067375 0.4319271979765523 0.09259523531903609 0.3982587474182624 2.5188867445066943 0.09381656563460312 0.02706340436378783 3.041538713683294e-09 8.516906651325987 -0.25453884002033467 (ac)AS(ph)IWVGHR ddPTM_PC-9_AZD4547_30min_R2 1 ASIWVGHR 8 0 P12429;D6RFG5;D6RCA8;D6RAZ8 P12429 ANXA3 Annexin A3;Annexin 1 AS(1)IWVGHR 67.035 0.028558999999999998 0.0 0.0 0.0 1054.5 2146.9 854.69 1871.7 1236.8 790.34 0.0 939.93 True False 0.0 0.0 1040.5166410019406 1651.9653742743512 736.0310465232917 1754.6623031160918 1346.8728040009223 668.2111132064448 0.0 907.0233367924258 0.0 0.0 1.1471773644563514 1.8213041575273239 0.8114797234723564 1.9345282882370314 1.4849373211983377 0.7367077406955036 0.0 1.0 9.824995860089249 -5.262993978672207 8.685100299160137 1.1646649075773388 3.539602924703198e-09 0.41246555421101316 0.5308525966417776 0.0964046538382375 112.23692082402783 0.14492773718649685 0.33641900907700295 5.457654278688725e-06 5.262993978672207 -1.164664904037736 (ac)AS(ph)LSLAPVNIFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASLSLAPVNIFK 12 0 P78371;F5GWF6;F8VQ14 P78371 CCT2 T-complex protein 1 subunit beta 1 AS(0.827)LS(0.173)LAPVNIFK 57.858999999999995 0.012329000000000001 0.0 0.0 0.0 0.0 0.0 564.76 0.0 0.0 444.36 0.0 0.0 True False 0.0 0.0 0.0 0.0 454.099332163582 0.0 0.0 432.6960208383377 0.0 0.0 0.0 (ac)AS(ph)PGHSDLGEVAPEIK ddPTM_PC-9_AZD4547_30min_R2 4 ASPGHSDLGEVAPEIK 16 0 F8WDN0;S4R325;Q8TCY9-2 F8WDN0 URGCP;URGCP-MRPS24 Up-regulator of cell proliferation 1 AS(0.998)PGHS(0.002)DLGEVAPEIK;AS(1)PGHSDLGEVAPEIK;AS(1)PGHSDLGEVAPEIK;AS(0.998)PGHS(0.002)DLGEVAPEIK 97.463 1.2667999999999998e-28 41457500.0 177760.0 152622.0 210655.0 281661.0 230898.0 203235.0 189356.0 220604.0 184851.0 214129.0 True False 234283.9823623077 201954.07681412145 207861.5770604683 216728.4080690709 198841.79828959628 190526.6833220062 206208.31716882132 186514.72077560853 194621.84647920416 206632.40888579492 1.1338201186620038 0.9773591563061186 1.005948573998151 1.0488597081054019 0.9622972473765986 0.9220561496106339 0.9979476030925624 0.9026402091585479 0.9418747404080792 1.0 17.656707023276446 -1.5228787452832129 0.4994719482199644 0.952225638447607 5.806741129727409 0.5494714056654707 0.04247911849356669 85.47286631981294 0.9095459614766287 0.02382922587807617 435.24499650277556 0.02999999999980138 1.5228787452832129 4.854515491279802 (ac)AS(ph)PGHSDLGEVAPEIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ASPGHSDLGEVAPEIK 16 0 F8WDN0;S4R325;Q8TCY9-2 F8WDN0 URGCP;URGCP-MRPS24 Up-regulator of cell proliferation 1 AS(0.999)PGHS(0.001)DLGEVAPEIK;AS(1)PGHSDLGEVAPEIK;AS(1)PGHSDLGEVAPEIK;AS(0.999)PGHS(0.001)DLGEVAPEIK 117.95 4.957699999999998e-69 37428900.0 114674.0 120181.0 116171.0 130388.0 139279.0 131626.0 129791.0 143248.0 122359.0 103991.0 True False 134086.0432852595 132111.77543144108 118940.95722097093 123082.78308359941 111988.27977266707 124723.30084566996 117496.25687453356 139487.89178380175 124148.26889451433 122843.74510769709 1.0915170582572706 1.0754456835846116 0.9682296572503176 1.0019458701433497 0.9116319245598298 1.0153003780235215 0.9564691858875242 1.135490387903045 1.0106193749276657 1.0 16.906464875630256 -10.646691274934557 14.956365112063594 0.9999959326823622 1.0166018132628372 0.006769065312292155 0.06358942055174159 0.0 0.0 0.063988895547606 0.015519586777023251 2.2558422432659483e-11 10.646691274934557 0.016605880580474963 (ac)AS(ph)PGHSDLGEVAPEIK ddPTM_PC-9_Lapatinib_30min_R1 4 ASPGHSDLGEVAPEIK 16 0 F8WDN0;S4R325;Q8TCY9-2 F8WDN0 URGCP;URGCP-MRPS24 Up-regulator of cell proliferation 1 AS(0.985)PGHS(0.015)DLGEVAPEIK;AS(1)PGHSDLGEVAPEIK;AS(0.999)PGHS(0.001)DLGEVAPEIK;AS(0.986)PGHS(0.014)DLGEVAPEIK 94.191 2.7799e-12 34294000.0 115102.0 98666.0 106215.0 102009.0 113621.0 100600.0 86702.0 79403.8 117759.0 89282.0 True False 113460.62437287833 98437.54493902097 97482.41270175655 109511.08215204829 106938.03616748062 96297.57251005377 91191.00532385577 83093.19042582347 104495.74136275568 104714.27473921327 1.0835258579161962 0.9400585085861097 0.9309371902210335 1.0458085339824132 1.0212364687986002 0.9196222076682384 0.8708555309289334 0.7935230476719984 0.9979130507564338 1.0 16.67609859952986 -6.866387561258395 5.117180014174704 0.8981642063340898 0.998711612267813 0.263051960688936 0.07075987106359274 0.26369263571741497 10.907564698897918 0.025166793086358535 0.022233383603574693 1.360230281008255e-07 6.866387561258395 0.10054740593372324 (ac)AS(ph)PGIEVELLGK ddPTM_PC-9_AZD4547_30min_R2 2 ASPGIEVELLGK 12 0 Q8TCY9 Q8TCY9 URGCP Up-regulator of cell proliferation 1 AS(1)PGIEVELLGK;AS(1)PGIEVELLGK 71.889 0.0013551 540190.0 9708.5 8686.2 11977.5 12853.2 11629.900000000001 11137.9 10027.1 11390.5 11858.1 9815.4 True False 12795.601050655192 11493.84428210102 11818.670524040523 9890.093319960446 10015.289131686608 10441.445352287601 10919.492474933413 9630.359952650766 12484.89495720905 9471.765833575242 1.3509203326477641 1.213484843698096 1.2477790025325626 1.0441657335850014 1.0573835235859295 1.102375790929614 1.1528465406340929 1.0167438809047986 1.3181169358044045 1.0 13.209417698935988 -5.678676460399679 6.19679201727569 1.1004219464799134 1.2686511021611875 0.4307831000346344 0.0907034550822591 0.19953861759408617 11.820307339999138 0.023625344440559363 0.04113775069769293 2.095673103682209e-06 5.678676460399679 0.16822915568127406 (ac)AS(ph)PGIEVELLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASPGIEVELLGK 12 0 Q8TCY9 Q8TCY9 URGCP Up-regulator of cell proliferation 1 AS(1)PGIEVELLGK 53.123999999999995 0.043876 528850.0 2063.1 3319.3 2719.8 2340.3 4723.5 3647.1 4157.8 3412.6 3798.5 2557.5 True False 2412.3420819176013 3648.818167510523 2784.6503468989386 2209.1805783549717 3797.964082928464 3455.8396556473876 3763.9430841347753 3323.022865948583 3854.0458764440164 3021.1545048411394 0.7984835194797324 1.207756227516205 0.9217172913324283 0.7312372057817468 1.2571234198193288 1.1438804768540314 1.2458624933294147 1.0999182135914352 1.2756864537276198 1.0 11.560884251471489 -6.281480481413694 24.99359021330225 1.1778537235213895 0.936218280802301 0.44321336843259074 0.13938130369261661 799.6482314229049 997251.9892631649 0.04254064928949893 0.04829590085717493 5.230214719156241e-07 6.281480481413694 -0.24163544271908854 (ac)AS(ph)PGKDNYR ddPTM_PC-9_Lapatinib_30min_R1 1 ASPGKDNYR 9 1 Q5TD90;O15131 Q5TD90 KPNA5 Importin subunit alpha-6 1 AS(1)PGKDNYR 66.429 0.010438 100750000.0 168940.0 135420.0 124780.0 159330.0 153260.0 160760.0 136860.0 146150.0 175660.0 131290.0 True False 166530.8846201981 135106.4433101801 114521.07006472898 171047.6597092991 144245.54812075317 153884.66954986358 143945.94113887698 152940.66254680595 155875.32101819533 153983.3015670712 1.0814866477431742 0.8774097056967646 0.7437239551253972 1.110819536719669 0.9367609776695396 0.9993594629014714 0.934815266811108 0.993228882549897 1.0122871729068623 1.0 17.232414383457197 -5.775739817289724 24.999905021971685 0.9927490664093804 0.8985269841533787 0.19969897778651213 0.08876603692062886 380.60074344404114 665362.3387994459 0.0249653445227989 0.03722432872503685 1.6759466229331201e-06 5.775739817289724 -0.0942220822560017 (ac)AS(ph)PPESDGFSDVRK ddPTM_PC-9_AZD4547_30min_R2 1 ASPPESDGFSDVRK 14 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 AS(1)PPESDGFSDVRK 127.51 6.3859e-07 51332000.0 111360.0 105850.0 143060.0 212960.0 184970.0 157720.0 120690.0 157390.0 135020.0 139670.0 True False 146770.1635681066 140063.9424904325 141162.93092625667 163865.3621992016 159290.1083146095 147857.74346715288 131431.1761924899 133068.99196239907 142156.88155120666 134780.19581223917 1.0889594178403668 1.0392026932914837 1.0473566244324888 1.2157970331745227 1.1818509934242478 1.0970287034834991 0.9751519902492591 0.9873037441478126 1.0547312288315998 1.0 17.040249001353722 -7.17846039955246 5.635576984005969 1.003529558314094 1.1144713990194635 0.4855643374894768 0.05427897241019205 0.2238602531412022 11.73478752927908 0.023810180074151203 0.018290872226957695 6.630398031380647e-08 7.17846039955246 0.1109418407053695 (ac)AS(ph)PPESDGFSDVRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASPPESDGFSDVRK 14 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 AS(0.971)PPES(0.029)DGFSDVRK;AS(1)PPESDGFSDVRK 95.48299999999999 0.00018827 12664000.0 39796.0 36184.0 33723.0 50525.0 44213.0 45259.0 45751.0 44147.0 38473.0 34273.0 True False 46532.676793171864 39776.10838827482 34527.08421518969 47694.24805426013 35549.780035676136 42885.53836608404 41417.134071444074 42988.18802761298 39035.594841234866 40486.423595081294 1.1493402642466333 0.9824554716437643 0.8528064755856675 1.1780306537141136 0.8780666919662197 1.0592572659664168 1.0229882116946445 1.0617926754299836 0.9641650552205681 1.0 15.305150586418465 (ac)AS(ph)PPESDGFSDVRK ddPTM_PC-9_Lapatinib_30min_R1 1 ASPPESDGFSDVRK 14 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 AS(0.996)PPES(0.004)DGFSDVRK 82.029 0.00013048 42074000.0 21088.0 19551.0 22123.0 18915.0 20865.0 15871.0 16545.0 14854.0 21708.0 14246.0 True False 20787.281252934423 19505.730860709864 20304.13233724959 20306.07219859029 19637.761722168303 15192.234327108008 17401.61914469327 15544.171067193023 19263.016444625904 16708.402118398204 1.2441214369652274 1.1674204823710475 1.2152049126763595 1.2153210136252686 1.1753225462861274 0.9092571641174059 1.041489127528942 0.9303206229443565 1.1528939935803153 1.0 14.028286149687684 -6.645871334799075 6.543716586650785 1.005235337802786 1.2059976183565613 0.7023630357518329 0.06424955408789451 0.11477595014997125 6.141789520124521 0.020060503751076233 0.02001293513119738 2.26010525564407e-07 6.645871334799075 0.2007622805537752 (ac)AS(ph)PSRQPPPGGSGLLQGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASPSRQPPPGGSGLLQGSR 19 1 Q96S90 Q96S90 LYSMD1 LysM and putative peptidoglycan-binding domain-containing protein 1 1 AS(0.567)PS(0.433)RQPPPGGSGLLQGSR 64.827 0.00033843 4723400.0 930.44 1331.1 1082.6 1428.5 1436.0 0.0 0.0 951.23 1439.3 0.0 True False 1087.9451149723295 1463.2428110665671 1108.4132897833636 1348.465776259486 1154.6261084122527 0.0 0.0 926.2612204114955 1460.347039611919 0.0 0.0 (ac)AS(ph)PSSFTYYCPPSSSPVWSEPLYSLRPEHAR ddPTM_PC-9_AZD4547_30min_R2 1 ASPSSFTYYCPPSSSPVWSEPLYSLRPEHAR 31 1 P49356 P49356 FNTB Protein farnesyltransferase subunit beta 1 AS(0.28)PS(0.28)S(0.28)FT(0.055)Y(0.052)Y(0.052)CPPS(0.001)S(0.001)SPVWSEPLYSLRPEHAR 45.269 0.00019015 3242800.0 0.0 0.0 0.0 817.54 1019.6 1179.2 1313.7 826.47 0.0 0.0 True False 0.0 0.0 0.0 629.0687838670885 878.0461395770961 1105.4644375885525 1430.6167550258838 698.7580518912497 0.0 0.0 0.0 (ac)AS(ph)PSSFTYYCPPSSSPVWSEPLYSLRPEHAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASPSSFTYYCPPSSSPVWSEPLYSLRPEHAR 31 1 P49356 P49356 FNTB Protein farnesyltransferase subunit beta 1 AS(0.385)PS(0.264)S(0.264)FT(0.063)Y(0.015)Y(0.005)CPPS(0.002)S(0.001)SPVWSEPLYSLRPEHAR 47.937 1.5205e-07 6127400.0 0.0 433.43 0.0 0.0 596.42 0.0 444.26 0.0 0.0 0.0 True False 0.0 476.4580659609209 0.0 0.0 479.5557824367939 0.0 402.17647663613343 0.0 0.0 0.0 0.0 (ac)AS(ph)PSSFTYYCPPSSSPVWSEPLYSLRPEHAR ddPTM_PC-9_Lapatinib_30min_R1 1 ASPSSFTYYCPPSSSPVWSEPLYSLRPEHAR 31 1 P49356 P49356 FNTB Protein farnesyltransferase subunit beta 1 AS(0.339)PS(0.314)S(0.314)FT(0.014)Y(0.013)Y(0.003)CPPS(0.001)S(0.001)SPVWSEPLYSLRPEHAR 45.269 4.731100000000001e-07 3263000.0 1071.6 1025.3 1366.4 568.03 765.88 739.55 616.1 1064.3 939.56 0.0 True False 1056.318787492628 1022.9259808442442 1254.0598664565314 609.8048210925317 720.8324441780146 707.9211704752523 647.9986433995477 1113.7512634181721 833.7368587945792 0.0 0.0 (ac)AS(ph)PTDGTDLEASLLSFEK ddPTM_PC-9_AZD4547_30min_R2 3 ASPTDGTDLEASLLSFEK 18 0 G3V5T8 G3V5T8 LIN52 1 AS(0.809)PT(0.191)DGTDLEASLLSFEK;AS(1)PTDGTDLEASLLSFEK;AS(0.499)PT(0.499)DGT(0.002)DLEASLLSFEK 189.3 7.474899999999999e-121 6414690.0 33129.0 39742.270000000004 51981.8 69016.7 58221.1 53282.7 43889.9 62703.7 44957.4 54289.3 True False 43663.33287399249 52588.181575051785 51292.48736769522 53105.966112385555 50138.10523433904 49950.924345912106 47796.0160739975 53014.283952682345 47333.756381648825 52388.64813137687 0.8334502689303303 1.0038087152616448 0.979076368587852 1.0136922407161537 0.9570414015762716 0.9534684731823658 0.9123353584947972 1.0119422020537072 0.9035116970941546 1.0 15.676966613854148 -1.5229020370329873 0.004380869417369318 1.869000386532552 4.686384579626776e-05 0.05053271123363123 0.054158694687676194 307471.1842212727 104.40291970348706 20868.301351822356 23758.473608749948 0.02999839110587065 1.5229020370329873 -1.8689535226867557 (ac)AS(ph)PTDGTDLEASLLSFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASPTDGTDLEASLLSFEK 18 0 G3V5T8 G3V5T8 LIN52 1 AS(0.831)PT(0.152)DGT(0.017)DLEASLLSFEK;AS(0.883)PT(0.117)DGTDLEASLLSFEK;AS(0.972)PT(0.027)DGTDLEASLLSFEK 148.68 3.0191999999999994e-91 3911880.0 31694.1 29560.4 35295.8 33546.1 43891.8 31799.6 40624.0 35477.1 33964.0 30239.3 True False 37059.28514299096 32494.961154122255 36137.38573206693 31666.620774923587 35291.51686992263 30131.972996003555 36775.800627709636 34545.86371609462 34460.659246424795 35721.445715832895 1.0374519955827288 0.909676540323211 1.0116439860677215 0.886487658613658 0.9879644052110772 0.8435261337322665 1.0295160201595486 0.96709030174506 0.9647050547887182 1.0 15.124502849842163 (ac)AS(ph)PTDGTDLEASLLSFEK ddPTM_PC-9_Lapatinib_30min_R1 3 ASPTDGTDLEASLLSFEK 18 0 G3V5T8 G3V5T8 LIN52 1 AS(0.5)PT(0.5)DGTDLEASLLSFEK;AS(0.5)PT(0.5)DGTDLEASLLSFEK;AS(0.975)PT(0.025)DGTDLEASLLSFEK 156.0 1.3634999999999998e-96 5659200.0 62890.4 70678.3 78129.7 66654.5 79122.9 82416.7 67800.9 67676.4 84958.3 65400.0 True False 61993.57136331311 70514.64873881196 71706.1776553635 71556.49428289368 74469.04658360666 78891.92986371134 71311.29884964836 70820.89260884497 75389.40160343933 76704.30285997778 0.8082150420750343 0.9193049947606601 0.9348390505062244 0.9328876166636789 0.9708587889723536 1.028520264472347 0.9296909846091133 0.9232975200638631 0.9828575294017238 1.0 16.2270198900108 -3.690635550052725 0.869809537144684 0.9659927966296341 3.0046018883159315e-12 0.7018305014114784 0.031076878057207866 7.566339777896797 1.0500496979623213 0.011151362536793247 10.849370871559714 0.00020387522340590118 3.690635550052725 -0.9659927966266295 (ac)ASAVS(ph)PANLPAVLLQPR ddPTM_PC-9_AZD4547_30min_R2 1 ASAVSPANLPAVLLQPR 17 0 P51610;A6NEM2;P51610-2;P51610-4;P51610-3 P51610 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 AS(0.17)AVS(0.83)PANLPAVLLQPR 93.23700000000001 2.0994e-05 8668800.0 0.0 0.0 0.0 769.21 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 591.880518676032 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)ASAVS(ph)PANLPAVLLQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASAVSPANLPAVLLQPR 17 0 P51610;A6NEM2;P51610-2;P51610-4;P51610-3 P51610 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 AS(0.394)AVS(0.606)PANLPAVLLQPR;AS(0.473)AVS(0.527)PANLPAVLLQPR 96.70700000000001 4.9618e-06 7007200.0 0.0 0.0 0.0 471.89 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 445.45153318802176 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)ASAVS(ph)PANLPAVLLQPR ddPTM_PC-9_Lapatinib_30min_R1 1 ASAVSPANLPAVLLQPR 17 0 P51610;A6NEM2;P51610-2;P51610-4;P51610-3 P51610 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 AS(0.008)AVS(0.992)PANLPAVLLQPR 88.10799999999999 0.00016092 8800700.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)ASCAS(ph)IDIEDATQHLR ddPTM_PC-9_AZD4547_30min_R2 2 ASCASIDIEDATQHLR 16 0 Q6P2E9 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 AS(0.094)CAS(0.906)IDIEDATQHLR;AS(0.004)CAS(0.996)IDIEDATQHLR 96.24700000000001 9.2278e-06 6281100.0 786.69 571.38 2841.7 4752.3 2478.07 1500.7199999999998 1594.42 2780.0 2728.46 649.57 True False 1036.841055831482 756.0674110551082 2804.0172012662047 3656.7306573030883 2134.0327551018204 1406.8797411617138 1736.3202911991855 2350.414878044787 2872.680825338511 626.8287520137204 1.6541057705163897 1.2061785752906224 4.473338519106138 5.8336996277781585 3.404490856946379 2.2444403461743554 2.770007415296706 3.7496921934323457 4.582879799482511 1.0 9.291927546094891 -5.250851896976019 24.604974556374977 3.6134991705514956 1.4301417659911566 0.2962248654345019 1.2722831728493185 701.4245979221831 1630078.3286882993 0.3353024055502536 0.8666169381418898 5.612393371367112e-06 5.250851896976019 -2.183357404560339 (ac)ASCAS(ph)IDIEDATQHLR ddPTM_PC-9_Lapatinib_30min_R1 2 ASCASIDIEDATQHLR 16 0 Q6P2E9 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 AS(0.482)CAS(0.518)IDIEDATQHLR;AS(0.021)CAS(0.979)IDIEDATQHLR 101.2 8.9307e-06 5534200.0 0.0 0.0 464.32 1674.62 461.92 1370.1799999999998 430.42 1563.24 1201.63 0.0 True False 0.0 0.0 426.1454019270317 1797.7771411685578 434.75077376966146 1311.5805954455827 452.7050415387655 1635.8738372881928 1066.289775675135 0.0 0.0 (ac)ASEDNRVPS(ph)PPPTGDDGGGGGR ddPTM_PC-9_AZD4547_30min_R2 1 ASEDNRVPSPPPTGDDGGGGGR 22 1 E9PEM5;A0A494C1L5;P50851-2;P50851;A0A494C0R9 E9PEM5 LRBA Lipopolysaccharide-responsive and beige-like anchor protein 1 AS(0.04)EDNRVPS(0.946)PPPT(0.015)GDDGGGGGR 77.726 0.00016031 21090000.0 0.0 0.0 0.0 1289.9 1601.9 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 992.5334837563399 1379.5038358067388 0.0 0.0 0.0 0.0 0.0 0.0 (ac)ASEDNRVPS(ph)PPPTGDDGGGGGR ddPTM_PC-9_Lapatinib_30min_R1 3 ASEDNRVPSPPPTGDDGGGGGR 22 1 E9PEM5;A0A494C1L5;P50851-2;P50851;A0A494C0R9 E9PEM5 LRBA Lipopolysaccharide-responsive and beige-like anchor protein 1 AS(0.238)EDNRVPS(0.744)PPPT(0.018)GDDGGGGGR;AS(0.009)EDNRVPS(0.742)PPPT(0.248)GDDGGGGGR;AS(0.002)EDNRVPS(0.994)PPPT(0.004)GDDGGGGGR 88.78 7.0354e-05 23401800.0 727.85 0.0 1667.46 1333.8200000000002 1399.29 0.0 1904.0300000000002 1468.72 1339.06 1828.43 True False 717.4707255286573 0.0 1530.3678753817383 1431.913572293084 1316.9865133099881 0.0 2002.6113569096585 1536.9620930259684 1188.2409618730778 2144.4716892701686 0.3345675902920571 0.0 0.7136339840898392 0.6677232343320929 0.6141309861536107 0.0 0.933848353853163 0.7167089687945684 0.5540949632575816 1.0 11.066406554695181 -7.330405833956526 0.15605208512053673 1.1853858650572353 8.898998474058081e-15 0.32553859839068866 0.2691022286800717 7.881347384731001 0.8714122700090102 2.2924217768629873 3.4205308943718413 4.672982622870554e-08 7.330405833956526 -1.1853858650572264 (ac)ASGEHS(ph)PGSGAAR ddPTM_PC-9_AZD4547_30min_R2 4 ASGEHSPGSGAAR 13 0 A6NKB8;Q9H4A4 A6NKB8 RNPEP Aminopeptidase B 1 AS(0.223)GEHS(0.774)PGS(0.003)GAAR;AS(0.101)GEHS(0.859)PGS(0.04)GAAR;AS(0.017)GEHS(0.976)PGS(0.007)GAAR;AS(0.137)GEHS(0.861)PGS(0.002)GAAR 96.70700000000001 1.7835999999999998e-19 335041400.0 11944.2 9654.3 11030.199999999999 14304.2 12508.0 13349.2 10367.5 13726.9 11989.4 13052.0 True False 15742.207145206357 12774.863674873703 10883.932340995349 11006.587687686973 10771.480103795926 12514.472413718715 11290.187415491238 11605.723017781647 12623.135207154783 12595.053452719614 1.2498721981848506 1.0142762571694575 0.8641434021580283 0.8738817766041598 0.8552151163336326 0.9936021677634485 0.896398531206978 0.921450874452276 1.0022295859672676 1.0 13.62056962435363 -4.8150953899081586 2.961221735857531 0.9204146989371843 1.291755713614263 0.7659497341338483 0.05389292884632835 0.16158534307984135 2.141663805364053 0.013901895316377876 0.13932867327213747 1.5307512053856183e-05 4.8150953899081586 0.3713410146770787 (ac)ASGEHS(ph)PGSGAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASGEHSPGSGAAR 13 0 A6NKB8;Q9H4A4 A6NKB8 RNPEP Aminopeptidase B 1 AS(0.377)GEHS(0.614)PGS(0.009)GAAR;AS(0.226)GEHS(0.766)PGS(0.008)GAAR;AS(0.008)GEHS(0.911)PGS(0.081)GAAR 81.185 1.0507e-14 133155400.0 7562.5 8781.0 9616.0 9215.1 10415.8 8523.1 9742.3 7938.0 9224.4 7727.1 True False 8842.681883816522 9652.719648392702 9845.281908883084 8698.807822757291 8374.898760445918 8076.133631939959 8819.438815856036 7729.635911006228 9359.289399149713 9127.962062310058 0.9687465639596076 1.057489019180897 1.0785848847394848 0.9529846600343824 0.9174992953823081 0.8847685361540703 0.966200205002173 0.8468085053642358 1.0253427145359006 1.0 13.156077080163476 -5.890288145863197 5.8111663179741795 0.9314015434260793 1.0365415494357557 0.36337598155453144 0.05580077522152848 0.19169975907814 9.090764004307363 0.015036769582958073 0.022592069441471983 1.287395106889969e-06 5.890288145863197 0.10514000600967643 (ac)ASGEHS(ph)PGSGAAR ddPTM_PC-9_Lapatinib_30min_R1 5 ASGEHSPGSGAAR 13 0 A6NKB8;Q9H4A4 A6NKB8 RNPEP Aminopeptidase B 1 AS(0.231)GEHS(0.762)PGS(0.007)GAAR;AS(0.082)GEHS(0.917)PGS(0.001)GAAR;AS(0.004)GEHS(0.809)PGS(0.188)GAAR;AS(0.011)GEHS(0.944)PGS(0.045)GAAR;AS(0.004)GEHS(0.987)PGS(0.009)GAAR 106.55 1.2687000000000002e-25 152508700.0 16558.199999999997 24694.4 17469.4 20340.2 24785.9 23934.9 22035.4 22073.4 19600.0 19548.8 True False 16322.077031598004 24637.221634019403 16033.133365834095 21836.086160918112 23328.042092954314 22911.260121977015 23176.28519195975 23099.010746908476 17392.441602850005 22927.784032861342 0.7118907351972751 1.0745574713503931 0.6992883979914736 0.952385373554699 1.017457337330084 0.999279306239947 1.0108384289882635 1.00746808822875 0.7585749053603356 1.0 14.484809304930875 -5.97038517489956 24.972469970288014 0.9712856481545085 0.8486200147883983 0.2049729698735353 0.11995915857885549 340.10286845988065 286786.85930789367 0.03221333722536892 0.047779421660626195 1.0705693982257717e-06 5.97038517489956 -0.12266563336611014 (ac)ASGVAVSDGVIK ddPTM_PC-9_AZD4547_30min_R2 2 ASGVAVSDGVIK 12 0 P23528;E9PP50;E9PS23 P23528 CFL1 Cofilin-1 0 ; 63.283 0.0022841999999999997 4323500.0 35350.0 39397.0 69359.0 100254.0 75338.0 72318.0 46537.0 79735.0 56556.0 66292.0 False True 46590.56467432261 52131.309799674666 68439.25434163456 77141.98920885974 64878.61912853982 67795.94402775522 50678.7028458853 67413.78787802186 59545.43469863767 63971.13725771441 0.7283060247409336 0.814919228177205 1.0698458285323251 1.2058874129138142 1.0141858017494598 1.0597895697028519 0.7922120040123853 1.0538156857590069 0.9308171974300327 1.0 15.965133510796038 -5.124945629614542 4.187939379095246 1.0175249464175877 0.7465258169978268 0.492773366902425 0.10048568350204404 0.1915191720256377 5.461570585607122 0.027489466772925766 0.08402735320017275 7.499880962944021e-06 5.124945629614542 -0.2709991294197609 (ac)ASGVAVSDGVIK ddPTM_PC-9_Lapatinib_30min_R1 4 ASGVAVSDGVIK 12 0 P23528;E9PP50;E9PS23 P23528 CFL1 Cofilin-1 0 ;;; 93.667 0.00060894 16418300.0 186198.0 175600.0 211801.0 190985.0 186013.0 192473.0 183791.0 156887.0 190564.0 162732.0 False True 183542.782375469 175193.4089888319 194387.5393555031 205030.6740072836 175072.08105562895 184241.37846647718 193306.79868373054 164176.54276415156 169100.67559211786 190860.0093732395 0.9616618115979383 0.9179157517813462 1.018482289683667 1.0742463792209735 0.9172800610800756 0.9653220654840315 1.0128198113293927 0.860193517244848 0.8859932269071107 1.0 17.542155322999577 -7.755686881266252 24.99960004168688 0.9048200270012521 0.9806319641849195 0.2187469586009938 0.05583782200190208 184.05455350317573 799886.9598804506 0.02756652155018199 0.015358168693687857 1.755145474997933e-08 7.755686881266252 0.07581193718366741 (ac)ASHLRPPS(ph)PLLVR ddPTM_PC-9_AZD4547_30min_R2 1 ASHLRPPSPLLVR 13 1 Q8TDB6;Q8TDB6-2 Q8TDB6 DTX3L E3 ubiquitin-protein ligase DTX3L 1 AS(0.036)HLRPPS(0.964)PLLVR 51.265 0.021009 4278000.0 2101.5 2217.9 3463.5 3503.8 3082.6 3210.8 2019.2 4609.1 2195.0 2126.6 True False 2769.733286084553 2934.7928016016067 3417.571726989303 2696.0530431703705 2654.634199549193 3010.028168427177 2198.9048882912853 3896.8695015813746 2311.023218818685 2052.148381286662 1.3496749608076477 1.4301075050730698 1.6653628744167828 1.3137710059152699 1.2935878437234558 1.4667692628249138 1.0715135944081244 1.8989218991748074 1.1261482063834551 1.0 11.00291933393409 -8.507547861834086 24.830555842239544 0.9999998439245167 1.4292284181458412 0.3416796092336226 0.21066536557714916 612.1217377884492 991418.8784868229 0.19214988712279402 0.04961288751155786 3.107793386556991e-09 8.507547861834086 0.42922857422132454 (ac)ASIWVGHR ddPTM_PC-9_Lapatinib_30min_R1 1 ASIWVGHR 8 0 P12429;D6RFG5;D6RCA8;D6RAZ8 P12429 ANXA3 Annexin A3;Annexin 0 79.939 0.0016792000000000003 1642700.0 1348.4 1055.4 3323.5 1728.1 1359.2 1568.3 2783.1 3190.1 3454.9 0.0 False True 1329.1715687337248 1052.956286143583 3050.254659081002 1855.1902387726059 1279.2545282900153 1501.2274648858595 2927.1953001871148 3338.323692032614 3065.7727802901272 0.0 0.0 (ac)ASLEVS(ph)RSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASLEVSRSPR 10 1 Q5QPJ9;Q5QPK2;O60762 Q5QPJ9 DPM1 Dolichol-phosphate mannosyltransferase subunit 1 1 ASLEVS(0.5)RS(0.5)PR 59.418 0.018181 159510000.0 49852.0 68107.0 59990.0 92026.0 48627.0 73417.0 73131.0 53692.0 75298.0 61970.0 True False 58290.95897811852 74868.2128565178 61420.389113341895 86870.08157231739 39098.888421840275 69566.88327675806 66203.50225741026 52282.64189137642 76399.09080017931 73204.67044574993 0.796273770828822 1.0227245393038231 0.8390228210761354 1.1866740338199397 0.5341037420667776 0.9503066246068584 0.9043617279374538 0.7141981730540229 1.043636838127653 1.0 16.15964807469777 -2.3062870304371907 18.587040731676584 0.89236940207708 0.2564837741866727 0.0 0.1771309957525687 0.0 0.0 0.03789733896611483 0.0 0.0049398409905398654 2.3062870304371907 -0.6358856278904074 (ac)ASLEVSRS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 ASLEVSRSPR 10 1 Q5QPJ9;Q5QPK2;O60762 Q5QPJ9 DPM1 Dolichol-phosphate mannosyltransferase subunit 1 1 ASLEVS(0.222)RS(0.778)PR 70.685 0.0015998 204280000.0 47884.0 37011.0 43650.0 47266.0 45906.0 47932.0 26372.0 28985.0 24353.0 33857.0 True False 63110.11595092686 48974.0819604477 43071.172479596644 36369.55395242044 39532.74429523949 44934.80446276673 28719.05691066649 24506.03425903889 25640.24986236513 32671.67673526876 1.9316460695388828 1.498976693399413 1.3183030925713626 1.113182964165407 1.210000472750891 1.3753443028609562 0.8790199885781971 0.7500696844427597 0.7847852459523978 1.0 14.995752876430817 -1.5228787452829236 0.3100424185058442 0.8420115791889059 10.437423936144523 0.8011960874429691 0.15400535659225725 25.963258108216017 0.37068925412831166 0.1676064033172484 139.7369909820503 0.029999999999821367 1.5228787452829236 9.595412356955617 (ac)ASLEVSRS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASLEVSRSPR 10 1 Q5QPJ9;Q5QPK2;O60762 Q5QPJ9 DPM1 Dolichol-phosphate mannosyltransferase subunit 1 1 ASLEVS(0.2)RS(0.8)PR 78.548 0.00025069 157260000.0 11151.0 7729.3 0.0 11127.0 7280.6 13423.0 9257.4 0.0 10130.0 5320.2 True False 13038.644057710819 8496.613822835858 0.0 10503.590264220731 5854.0186942244045 12719.074250158988 8380.472054228017 0.0 10278.132085922833 6284.710145319972 2.0746611627618643 1.351949990750651 0.0 1.671292712209238 0.9314699578601425 2.02381238848867 1.33346993901838 0.0 1.6354186347920336 1.0 12.617630492863562 -4.829656231831904 4.341028909648021 1.075158057445523 2.1021449905273095 0.18363500514017628 0.6317192750940611 0.33065296031650937 10.881163220661977 0.15693273115841652 0.8877982352111629 1.4802796479851602e-05 4.829656231831904 1.0269869330817865 (ac)ASLEVSRS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 ASLEVSRSPR 10 1 Q5QPJ9;Q5QPK2;O60762 Q5QPJ9 DPM1 Dolichol-phosphate mannosyltransferase subunit 1 1 ASLEVS(0.027)RS(0.973)PR;AS(0.004)LEVS(0.364)RS(0.632)PR 96.334 0.00015984 151862400.0 0.0 1451.1 8637.1 0.0 0.0 6779.0 0.0 0.0 0.0 0.0 True False 0.0 1447.7400671053185 7926.990978170158 0.0 0.0 6489.077972620825 0.0 0.0 0.0 0.0 0.0 (ac)ASNSWNAS(ph)SSPGEAREDGPEGLDK ddPTM_PC-9_AZD4547_30min_R2 1 ASNSWNASSSPGEAREDGPEGLDK 24 1 Q99594 Q99594 TEAD3 Transcriptional enhancer factor TEF-5 1 AS(0.012)NS(0.013)WNAS(0.325)S(0.325)S(0.325)PGEAREDGPEGLDK 56.533 1.5329e-06 3592800.0 8822.6 8426.9 11489.0 12840.0 12676.0 10225.0 10734.0 13422.0 11643.0 11069.0 True False 11628.003278519915 11150.730627988885 11336.648353220759 9879.936376022488 10916.156203687002 9585.62913360155 11689.30520548666 11347.938306876656 12258.425210344407 10681.47767914138 1.088613731902178 1.0439314636928798 1.0613370821678338 0.9249596987236953 1.0219706047791401 0.8974066530439148 1.0943528186473066 1.0623940476921774 1.1476338366818353 1.0 13.382823623288656 (ac)ASNSWNAS(ph)SSPGEAREDGPEGLDK ddPTM_PC-9_Lapatinib_30min_R1 1 ASNSWNASSSPGEAREDGPEGLDK 24 1 Q99594 Q99594 TEAD3 Transcriptional enhancer factor TEF-5 1 AS(0.006)NS(0.065)WNAS(0.409)S(0.409)S(0.111)PGEAREDGPEGLDK 61.963 4.1231e-06 4694200.0 9422.7 13849.0 15189.0 13566.0 15708.0 16551.0 15406.0 16665.0 18134.0 13920.0 True False 9288.330570088452 13816.933491380016 13940.219051235536 14563.68889484937 14784.086323116218 15843.152312265423 16203.647297863057 17439.31673857355 16091.55796051439 16326.053452765898 0.5689268748850542 0.8463119106742361 0.8538633719145294 0.8920520159378779 0.9055517529627808 0.9704214406808362 0.9925024038873214 1.0681893691594553 0.9856367313184449 1.0 13.994888465474084 -4.043382513399784 0.49127380548576205 1.0123074399624994 6.228171738694044e-18 0.8777079523260256 0.04601683639441127 3.074802532510075 0.33060978407447733 0.028602439019461932 2.0956712387423515 9.049352103205675e-05 4.043382513399784 -1.0123074399624994 (ac)ASNSWNASSS(ph)PGEAREDGPEGLDK ddPTM_PC-9_Lapatinib_30min_R1 1 ASNSWNASSSPGEAREDGPEGLDK 24 1 Q99594 Q99594 TEAD3 Transcriptional enhancer factor TEF-5 1 AS(0.002)NS(0.041)WNAS(0.283)S(0.283)S(0.391)PGEAREDGPEGLDK 47.99100000000001 1.3757e-06 3687000.0 8958.2 15389.0 15220.0 12396.0 13691.0 16545.0 14459.0 14938.0 13268.0 15207.0 True False 8830.454425267319 15353.36771599734 13968.670350899 13307.643191843783 12885.722297541644 15837.408918278754 15207.616271569648 15632.074013850093 11773.618121766009 17835.509687946193 0.49510524676708406 0.8608314527940649 0.7831943462955518 0.7461319258421594 0.7224756972462765 0.8879706380907175 0.8526594718987729 0.8764579362940633 0.6601223249438728 1.0 14.122464824048626 -1.5728542602567215 0.07898397815670097 1.0999432774261952 1.6895664754429656e-27 0.34555150701907933 0.10867321149002206 254.8572041722225 1.4892168900660372 3.207176098005892 30.66235116406567 0.026739035617605544 1.5728542602567215 -1.0999432774261952 (ac)ASPS(ph)RQPPPGGSGLLQGSR ddPTM_PC-9_Lapatinib_30min_R1 1 ASPSRQPPPGGSGLLQGSR 19 1 Q96S90 Q96S90 LYSMD1 LysM and putative peptidoglycan-binding domain-containing protein 1 1 AS(0.216)PS(0.784)RQPPPGGSGLLQGSR 73.597 0.00010793 5112600.0 7901.7 8490.6 8888.8 7093.2 8204.4 8815.9 8449.0 8417.5 11831.0 5791.7 True False 7789.020309005687 8470.940537360913 8157.997175760253 7614.857590221551 7721.833322471013 8438.86450786664 8886.4478787255 8808.60777959454 10498.468194046854 6792.787628044848 1.1466603602985865 1.2470492235599429 1.2009792772085164 1.1210210015668216 1.1367694303573523 1.2423271519671486 1.3082181227095517 1.296758895159203 1.545531638690227 1.0 12.729788034659348 -7.048726780583718 3.1863245879086413 1.3120662455713183 1.1739916695168482 0.1464367046763515 0.12786202759014442 0.41762958293187563 8.469237982051174 0.04924678705786448 0.03871020996503411 8.938676488128799e-08 7.048726780583718 -0.13807457605447016 (ac)ATAAETS(ph)ASEPEAESK ddPTM_PC-9_Lapatinib_30min_R1 1 ATAAETSASEPEAESK 16 0 A0A494C0L2;F8W667;A0A499FI31;Q15020-3;Q15020-2;Q15020-4;Q15020 A0A494C0L2 SART3 Squamous cell carcinoma antigen recognized by T-cells 3 1 ATAAET(0.03)S(0.969)AS(0.001)EPEAESK 114.69 4.2445e-21 0.0 25166.0 19600.0 23505.0 21373.0 22108.0 18317.0 19027.0 19220.0 22926.0 20556.0 True False 24807.12822512082 19554.617404220407 21572.509631923844 22944.841718237898 20807.65090600034 17533.624609012495 20012.124960173984 20113.031366059644 20343.832458517296 24109.077210851723 1.028953866967372 0.8110894180312588 0.8947878611552106 0.9517096617829158 0.8630629336835265 0.7272623690931002 0.830065986564029 0.8342513979343257 0.8438246010245612 1.0 14.557288811543149 -6.515673605914805 24.875976384725075 0.8311586578217469 0.9112670264674688 0.14332356744287733 0.08078733689678706 546.4459456052928 1886629.3064531893 0.025089275177130565 0.026092916548823432 3.0501864965632336e-07 6.515673605914805 0.0801083686457219 (ac)ATAT(ph)PVPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATATPVPPR 9 0 P20700;E9PBF6;A0A0D9SFE5;A0A0D9SFY5 P20700 LMNB1 Lamin-B1 1 AT(0.016)AT(0.984)PVPPR 53.751000000000005 0.00085386 7730200.0 0.0 0.0 1129.4 966.22 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 1156.3291792733514 912.0858259275047 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)ATDELAT(ph)KLSR ddPTM_PC-9_AZD4547_30min_R2 2 ATDELATKLSR 11 1 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 ATDELAT(0.904)KLS(0.096)R;ATDELAT(0.914)KLS(0.086)R 59.367 0.0023233 5571900.0 16047.1 15709.1 25783.0 33941.0 30111.0 21555.1 22936.0 28511.0 20294.1 24741.0 True False 21149.743999584796 20786.759366806327 25441.100573687076 26116.42683322267 25930.60740369354 20207.256189505613 24977.259567080513 24105.280067602474 21366.804694773724 23874.825120574318 0.8858596405532972 0.8706559843612498 1.065603640872871 1.0938897646926273 1.086106694928108 0.8463834221802049 1.0461756030018483 1.0096526339298528 0.8949512545899535 1.0 14.543202545217031 -5.246813010563101 24.49418359622897 1.0075177553437211 0.8782577778884663 0.31044140392164066 0.07570791862372758 761.4186119529302 1275109.5903247904 0.02002129999196202 0.052407835872724205 5.664831410038092e-06 5.246813010563101 -0.12925997745525486 (ac)ATDELATKLS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATDELATKLSR 11 1 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 ATDELAT(0.006)KLS(0.994)R;ATDELAT(0.01)KLS(0.99)R 63.966 0.0013368 38166000.0 52143.0 46338.0 43673.0 50365.0 51089.0 43356.0 46476.0 57395.0 41445.0 32935.0 True False 60969.7800288059 50938.13040282664 44714.32995077482 47543.212335533084 41078.477195455125 41082.335036124045 42073.4568228986 55888.44206502924 42051.05471876325 38905.85478668346 1.5671106665846701 1.3092664505667546 1.1492956573230069 1.222006625897498 1.055843070938395 1.0559422292961813 1.0814171042785914 1.4365046693218653 1.0808413013754503 1.0 15.247699656512301 -4.673708169120589 1.455329608997311 1.1416151780946615 1.825960582553314 0.5703434333276769 0.11639542185187972 1.1729154013386707 1.897730776478215 0.03398735331478866 1.2595772511069296 2.1197850790721003e-05 4.673708169120589 0.6843454044586526 (ac)ATDELATKLS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 ATDELATKLSR 11 1 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 ATDELAT(0.027)KLS(0.973)R 65.234 0.0021680999999999996 21135000.0 18255.0 17841.0 13003.0 15231.0 13762.0 18536.0 17195.0 14451.0 18515.0 16065.0 True False 17994.680352443 17799.690260647767 11933.943533031514 16351.138549126537 12952.54621713301 17743.258489526423 18085.272964218828 15122.446215969185 16429.645728406518 18841.81384473306 0.9550397058759359 0.9446909096611947 0.6333755142351895 0.8678112778243612 0.6874362693458886 0.9416958810728447 0.9598477680148766 0.8026003409537151 0.8719779244076957 1.0 14.201650235096768 (ac)ATDTS(ph)QGELVHPK ddPTM_PC-9_Lapatinib_30min_R1 1 ATDTSQGELVHPK 13 0 Q5SSJ5;B0QZK9;B0QZK8;Q5SSJ5-5 Q5SSJ5 HP1BP3 Heterochromatin protein 1-binding protein 3 1 AT(0.032)DT(0.065)S(0.904)QGELVHPK 74.32600000000001 0.0023488000000000003 4430200.0 54306.0 55155.0 65033.0 47425.0 41108.0 44072.0 45766.0 42297.0 44037.0 31798.0 True False 53531.5864814993 55027.29198621312 59686.23777463963 50912.79270516223 38690.108261437555 42187.143296849856 48135.53954524219 44262.273032790006 39077.08932983194 37294.241931828285 1.4353847593779205 1.475490293831413 1.6004142914003352 1.3651649709954654 1.0374284677018193 1.1311972334486786 1.2906962858564377 1.1868393280040088 1.0478048971008072 1.0 15.186665281406471 -6.060612715050106 4.499741879025866 1.1362279308875403 1.5001235088551115 0.7985311884618076 0.08853894785952858 0.09946670541175158 4.063574294056912 0.027289231806611348 0.036837719024662874 8.69735676057184e-07 6.060612715050106 0.3638955779675712 (ac)ATEIGS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 1 ATEIGSPPR 9 0 Q9C0J8;B9A053;Q9C0J8-3;Q9C0J8-2 Q9C0J8 WDR33 pre-mRNA 3 end processing protein WDR33 1 ATEIGS(1)PPR 53.568999999999996 0.024017 2392500.0 28350.0 26921.0 23412.0 24729.0 21083.0 19488.0 22223.0 20332.0 18102.0 15437.0 True False 27945.723801246724 26858.666078521295 21487.15573293348 26547.653153525716 19842.939390772808 18654.543668746825 23373.598202025874 21276.69894561521 16063.162137489331 18105.264881490457 1.543513667663402 1.4834726945077559 1.186790465291697 1.466294656681116 1.0959761992247254 1.0303380696638087 1.2909834987236994 1.1751663996568757 0.8872094522025564 1.0 14.144121663263142 -1.5228787452803378 0.22498705727316876 0.9762638386470808 4.2324282884880535 0.6438869493549507 0.12704411076927777 33.19825902379299 0.4295978458204182 0.19418695439020314 39.52705866194232 0.02999999999999998 1.5228787452803378 3.2561644498409725 (ac)ATES(ph)PATRR ddPTM_PC-9_Lapatinib_30min_R1 1 ATESPATRR 9 1 H0YN31;Q01415 H0YN31 GALK2 N-acetylgalactosamine kinase 1 AT(0.001)ES(0.874)PAT(0.124)RR 54.066 0.042983 1163100.0 0.0 0.0 893.45 0.0 0.0 902.12 0.0 0.0 1160.7 0.0 True False 0.0 0.0 819.9939898167355 0.0 0.0 863.5384305444317 0.0 0.0 1029.9697432871433 0.0 0.0 (ac)ATFVELSTK ddPTM_PC-9_Lapatinib_30min_R1 2 ATFVELSTK 9 0 O60218;C9JRZ8 O60218 AKR1B10;AKR1B15 Aldo-keto reductase family 1 member B10;Aldo-keto reductase family 1 member B15 0 ; 90.709 0.00022373 13084200.0 143534.0 133800.0 157307.0 138393.0 149961.0 146028.0 148700.0 122353.0 130265.0 142330.0 False True 141487.17883908792 133490.19432064754 144373.82568258015 148570.88288551423 141140.5888146695 139782.7228478943 156398.95840531215 128037.96705158686 115593.18394873744 166931.55085719607 0.8475760161128864 0.7996702458892483 0.8648684142765004 0.8900107985734301 0.8454997757458695 0.8373655077791339 0.9369047229370427 0.7670087912926582 0.6924585757166016 1.0 17.34889713113467 -9.992680711517616 5.911917944058546 0.9999999989126886 0.8348652001299065 0.38494173963151235 0.0638412315660073 14818264.184218984 0.3929575463196072 0.07235103410345625 0.01607800758802408 1.0169961023391409e-10 9.992680711517616 -0.16513479878278214 (ac)ATS(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 1 ATSPQK 6 0 Q9NVD7-2;Q9NVD7 Q9NVD7-2 PARVA Alpha-parvin 1 AT(0.169)S(0.831)PQK 48.56100000000001 0.022266 2448900.0 26948.0 53368.0 22187.0 50482.0 58627.0 18760.0 113160.0 77494.0 34782.0 35474.0 True False 26563.71657834204 53244.429674920175 20362.870504296727 54194.6146830153 55178.6751251168 17957.67853169594 119018.87110386748 81094.65414575579 30864.4848893025 41605.6336338662 0.6384644159515858 1.2797408673901367 0.48942579948408077 1.302578760365325 1.3262308563954281 0.43161651351654284 2.8606431559544467 1.9491267663268148 0.7418342708324815 1.0 15.344491270063749 -7.221643645621459 24.999973646343502 1.716997321245652 0.94555225894735 0.24637127606782994 0.6146048100430891 711.30785715023 446849.36254266195 0.2323675481181333 0.1799882387650796 6.002834285627497e-08 7.221643645621459 -0.771445062298302 (ac)ATSAT(ph)SPHAPGFPAEGR ddPTM_PC-9_AZD4547_30min_R2 2 ATSATSPHAPGFPAEGR 17 0 Q5VVL2;Q9NUP7-2;Q9NUP7 Q5VVL2 TRMT13 tRNA:m(4)X modification enzyme TRM13 homolog 1 AT(0.182)S(0.033)AT(0.653)S(0.131)PHAPGFPAEGR;AT(0.053)S(0.013)AT(0.669)S(0.265)PHAPGFPAEGR 79.471 0.00037839 7534100.0 1054.0 832.01 1693.0 3282.4 3236.17 3058.1 3408.3 3886.5 2609.0 3195.8 True False 1389.1500754380775 1100.9409616576718 1670.5497138134515 2525.6933925744715 2786.8836558603475 2866.876523566446 3711.632097248016 3285.9307278852725 2746.906413620934 3083.916014725814 0.45045003456800836 0.356994469499376 0.5416975384013424 0.8189890322934189 0.9036833826060353 0.9296221135326006 1.2035451288312764 1.0655059061903212 0.8907202402738446 1.0 11.590547761073132 -5.8630534929207965 1.2264128425232328 1.0312266926714475 0.3715370091793322 0.8947551342749386 0.08534296877533262 0.1451980551175818 0.43860424545087257 0.032317497342832305 0.07340491582123691 1.370712922311832e-06 5.8630534929207965 -0.6596896834921153 down (ac)ATSAT(ph)SPHAPGFPAEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATSATSPHAPGFPAEGR 17 0 Q5VVL2;Q9NUP7-2;Q9NUP7 Q5VVL2 TRMT13 tRNA:m(4)X modification enzyme TRM13 homolog 1 AT(0.088)S(0.088)AT(0.412)S(0.412)PHAPGFPAEGR 63.662 0.036412 3631700.0 891.87 2006.2 2244.6 4627.3 2554.0 1404.6 1222.4 1962.4 2092.0 860.51 True False 1042.8459757645537 2205.3622774860974 2298.119776692902 4368.047382909012 2053.5620340424043 1330.9403033430176 1106.605422590396 1910.8890793346704 2122.591542324834 1016.5136512065885 1.0259045459219451 2.169535327802397 2.2607859461258233 4.297086790447129 2.020201137097227 1.3093186714838594 1.0886281962636408 1.8798459588481373 2.0881092347410637 1.0 9.989413874557771 -6.523535749404262 24.24082760702489 1.521983007782748 2.500471524034434 0.23957971114415721 0.8076630300013437 23.852961845750457 879996.4663939147 0.2791316797557186 0.28174855429397316 2.995465007445827e-07 6.523535749404262 0.9784885162516861 (ac)ATSATS(ph)PHAPGFPAEGR ddPTM_PC-9_Lapatinib_30min_R1 2 ATSATSPHAPGFPAEGR 17 0 Q5VVL2;Q9NUP7-2;Q9NUP7 Q5VVL2 TRMT13 tRNA:m(4)X modification enzyme TRM13 homolog 1 AT(0.002)S(0.008)AT(0.418)S(0.572)PHAPGFPAEGR;AT(0.238)S(0.238)AT(0.238)S(0.286)PHAPGFPAEGR 74.726 0.009461399999999998 6698100.0 1538.2 2616.7 1361.2 1592.8 3196.6000000000004 3041.3 1771.63 1855.0700000000002 7605.200000000001 2149.85 True False 1516.2649859286678 2610.6411919195693 1249.28739038395 1709.9398254250382 3008.5822727574036 2911.23068861657 1863.3563327478344 1941.2633244659862 6748.62228969362 2521.448708004941 0.6013467500310129 1.0353735071554164 0.49546412997329226 0.6781576876802712 1.193195904880373 1.15458651979482 0.7390022754903419 0.7698999857910979 2.6764860487816016 1.0 11.30003716256111 -8.225999100347625 24.931253483875388 1.8382435389673455 0.8432285465308548 0.4614576149888683 0.43411740816438327 409.29366007392895 287927.59273901826 0.2734591396195622 0.1033488009374909 5.942933897085934e-09 8.225999100347625 -0.9950149924364907 (ac)ATTATMATSGS(ph)AR ddPTM_PC-9_AZD4547_30min_R2 4 ATTATMATSGSAR 13 0 I3L3H2;P38919 I3L3H2 EIF4A3 Eukaryotic initiation factor 4A-III;Eukaryotic initiation factor 4A-III, N-terminally processed 1 ATTATMAT(0.002)S(0.041)GS(0.957)AR;ATTATMATS(0.017)GS(0.983)AR;ATTATMAT(0.005)S(0.035)GS(0.959)AR;ATTATMAT(0.009)S(0.051)GS(0.94)AR 101.3 1.1139000000000001e-07 14906400.0 16926.0 24666.399999999998 27131.399999999998 44588.4 42334.0 33052.3 18858.1 47245.7 38932.2 29464.2 True False 22308.11591732913 32639.331422257925 26771.619908658155 34309.233263912865 36456.654838031376 30985.53445599399 20536.434367019556 39944.962663180035 40990.07661033842 28432.66732620451 0.7845945532084925 1.1479517924854137 0.9415796133901416 1.206683596381839 1.2822101570622495 1.0897864101352415 0.722283074303496 1.4048967761236175 1.4416542823810476 1.0 14.795261827062294 -4.173286261280365 1.1225132255817099 1.1517085912651401 1.0052579093919528e-24 0.19971076336390392 0.20670156205834128 10.227608610692974 4.106866387705693 0.06610473130957019 19.391722731563778 6.709864324940956e-05 4.173286261280365 -1.1517085912651401 (ac)ATTATMATSGS(ph)AR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATTATMATSGSAR 13 0 I3L3H2;P38919 I3L3H2 EIF4A3 Eukaryotic initiation factor 4A-III;Eukaryotic initiation factor 4A-III, N-terminally processed 1 ATTATMAT(0.02)S(0.101)GS(0.879)AR;ATTATMAT(0.029)S(0.058)GS(0.913)AR 74.296 0.00053197 18745300.0 8124.3 8800.0 10677.2 8032.2 16900.0 12352.5 8307.3 7653.299999999999 8143.4 8592.7 True False 9499.583527760731 9673.605842826071 10931.784941506488 7582.181874743754 13588.566317665089 11704.713154666537 7520.372404356347 7452.408984341638 8262.481819200792 10150.488490224232 0.9358745184440752 0.9530187490131693 1.0769713154233622 0.7469770427350396 1.3387105783876325 1.1531182135656972 0.74088773280213 0.7341921515914165 0.8139984422580501 1.0 13.30926153804029 -7.2707266951700715 24.94203581622574 0.8001189188718879 1.0331676803360628 0.2927422380075805 0.15983054366828606 811.6927684678606 2179874.9881746373 0.06783301370604958 0.04643231710439285 5.36133944554085e-08 7.2707266951700715 0.23304876146417486 (ac)ATTATMATSGS(ph)AR ddPTM_PC-9_Lapatinib_30min_R1 4 ATTATMATSGSAR 13 0 I3L3H2;P38919 I3L3H2 EIF4A3 Eukaryotic initiation factor 4A-III;Eukaryotic initiation factor 4A-III, N-terminally processed 1 ATTATMAT(0.005)S(0.064)GS(0.931)AR;ATTATMAT(0.004)S(0.056)GS(0.94)AR;ATTATMAT(0.04)S(0.124)GS(0.835)AR;ATTATMATS(0.002)GS(0.998)AR 130.61 3.9656999999999993e-26 10840300.0 24152.4 12334.7 19287.8 19204.800000000003 20028.1 17736.8 10692.6 16322.4 22982.1 16768.4 True False 23807.98234699228 12306.139759991705 17702.031537061084 20617.185057334744 18850.086534759605 16978.23841050024 11246.210508706385 17080.798291850777 20393.613885758128 19666.795597511464 1.210567437331012 0.6257318178233805 0.9000973976310106 1.0483245709811282 0.9584726927829971 0.8632945985694069 0.5718374634518204 0.8685094736029134 1.0369566198338194 1.0 14.263474291300096 -6.875951362165473 6.225278150043841 0.8394014979544852 0.9330494704814488 0.03370740941895933 0.1799669389703333 0.7334763587188967 37.25095508047163 0.06456860493608817 0.05698053275084604 1.330603427574593e-07 6.875951362165473 0.09364797252696366 (ac)ATTATMATSGS(ph)ARK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATTATMATSGSARK 14 1 I3L3H2;P38919 I3L3H2 EIF4A3 Eukaryotic initiation factor 4A-III;Eukaryotic initiation factor 4A-III, N-terminally processed 1 ATTAT(0.001)MAT(0.303)S(0.198)GS(0.498)ARK 54.093999999999994 0.00026312 0.0 8654.1 8338.6 7737.2 9780.6 10659.0 9814.1 9460.6 10809.0 9533.6 6280.8 True False 10119.068203733766 9166.401100112447 7921.684191494398 9232.624691133035 8570.445466271729 9299.43131926435 8564.423479187419 10525.275203082176 9673.010864200784 7419.459321214553 1.3638552036804337 1.23545405443532 1.0676902249256663 1.2443797170952977 1.1551307305865466 1.2533839619113982 1.1543190828877592 1.418604071726241 1.303735278464648 1.0 12.857098341720626 (ac)ATVVVEATEPEPSGSIANPAAS(ph)TSPSLSHR ddPTM_PC-9_AZD4547_30min_R2 1 ATVVVEATEPEPSGSIANPAASTSPSLSHR 30 0 P46821;D6RA32;D6RGJ3;D6RCL2 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ATVVVEAT(0.001)EPEPS(0.024)GS(0.019)IANPAAS(0.314)T(0.314)S(0.249)PS(0.075)LS(0.004)HR 66.281 1.0352000000000001e-09 8635600.0 411.0 548.48 460.5 0.0 658.81 561.38 0.0 0.0 0.0 0.0 True False 541.6894506689281 725.7654338890156 454.3934691146454 0.0 567.3456033883746 526.276819855378 0.0 0.0 0.0 0.0 0.0 (ac)ATVVVEATEPEPSGSIANPAAS(ph)TSPSLSHR ddPTM_PC-9_Lapatinib_30min_R1 3 ATVVVEATEPEPSGSIANPAASTSPSLSHR 30 0 P46821;D6RA32;D6RGJ3;D6RCL2 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ATVVVEATEPEPS(0.001)GS(0.001)IANPAAS(0.383)T(0.29)S(0.29)PS(0.033)LS(0.002)HR;ATVVVEATEPEPSGS(0.001)IANPAAS(0.584)T(0.109)S(0.203)PS(0.099)LS(0.004)HR;ATVVVEATEPEPSGSIANPAAS(0.626)T(0.137)S(0.172)PS(0.062)LS(0.003)HR 112.02 1.0857999999999998e-15 24033300.0 747.04 2617.4399999999996 1854.2200000000003 1704.65 1160.39 1253.59 545.26 1071.2 0.0 1324.0 True False 736.3870726096426 2611.379478495035 1701.7731890961857 1830.0156475457009 1092.1381416145164 1199.976877961018 573.4908948223301 1120.9718626078602 0.0 1552.8516358808943 0.47421598792463415 1.6816670814875783 1.095901984306963 1.1784871170307125 0.7033113250352301 0.7727569397061561 0.3693146734504375 0.7218795644774916 0.0 1.0 10.60070428154521 -6.520608694303615 1.5868345534121433 0.5153031495218141 1.1577020944728083 0.3140769045542162 0.3700106509337371 0.4047396724419627 2.0751189320515455 0.13915188198182046 0.1532822050212638 3.0157220101823864e-07 6.520608694303615 0.6423989449509941 (ac)ATVVVEATEPEPSGSIANPAAST(ph)SPSLSHR ddPTM_PC-9_AZD4547_30min_R2 2 ATVVVEATEPEPSGSIANPAASTSPSLSHR 30 0 P46821;D6RA32;D6RGJ3;D6RCL2 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ATVVVEATEPEPS(0.001)GS(0.002)IANPAAS(0.144)T(0.362)S(0.362)PS(0.113)LS(0.016)HR;ATVVVEATEPEPSGSIANPAAS(0.052)T(0.389)S(0.389)PS(0.148)LS(0.022)HR 113.64 5.3723e-15 48563000.0 3298.8 4572.7 1224.8 2422.8 2427.66 681.53 1036.6 1177.4 2391.3 1348.7 True False 4347.749780697467 6050.735850977795 1208.558351729896 1864.260891886859 2090.621313461881 638.9138213617081 1128.8553918397126 995.4598839604068 2517.699236064294 1301.4824235123306 3.340613520514651 4.649110692289321 0.9286013624896609 1.4324134219621265 1.6063384919328294 0.49091237024735346 0.8673612270485016 0.7648661756598633 1.9344857760504675 1.0 10.345940112975128 -5.267128474535378 24.997401167244828 1.1156009303220469 3.99486218738937 0.840714295979694 0.49910475656482917 142.73664079132305 627175.1292566522 0.12759438155117564 0.2777910688597285 5.405943787408923e-06 5.267128474535378 2.8792612570673235 (ac)ATVVVEATEPEPSGSIANPAAST(ph)SPSLSHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATVVVEATEPEPSGSIANPAASTSPSLSHR 30 0 P46821;D6RA32;D6RGJ3;D6RCL2 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ATVVVEATEPEPS(0.001)GS(0.012)IANPAAS(0.178)T(0.407)S(0.299)PS(0.098)LS(0.005)HR 72.811 4.328399999999999e-09 7966800.0 0.0 697.61 0.0 0.0 853.56 501.59 429.39 0.0 443.86 0.0 True False 0.0 766.864110456125 0.0 0.0 686.3110453317287 475.28573740127 388.7150706856105 0.0 450.3506127993786 0.0 0.0 (ac)ATVVVEATEPEPSGSIANPAAST(ph)SPSLSHR ddPTM_PC-9_Lapatinib_30min_R1 1 ATVVVEATEPEPSGSIANPAASTSPSLSHR 30 0 P46821;D6RA32;D6RGJ3;D6RCL2 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ATVVVEATEPEPSGS(0.005)IANPAAS(0.037)T(0.461)S(0.345)PS(0.148)LS(0.003)HR 95.82700000000001 1.8646e-15 15193000.0 0.0 1202.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 1199.4163797629478 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)ATVVVEATEPEPSGSIANPAASTS(ph)PSLSHR ddPTM_PC-9_AZD4547_30min_R2 1 ATVVVEATEPEPSGSIANPAASTSPSLSHR 30 0 P46821;D6RA32;D6RGJ3;D6RCL2 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ATVVVEATEPEPSGSIANPAAS(0.04)T(0.157)S(0.637)PS(0.157)LS(0.01)HR 89.833 1.4609e-16 6966400.0 0.0 1662.0 0.0 0.0 0.0 0.0 0.0 731.42 522.3 0.0 True False 0.0 2199.208997818598 0.0 0.0 0.0 0.0 0.0 618.3958453595387 549.9077117034168 0.0 0.0 (ac)ATVVVEATEPEPSGSIANPAASTS(ph)PSLSHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ATVVVEATEPEPSGSIANPAASTSPSLSHR 30 0 P46821;D6RA32;D6RGJ3;D6RCL2 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ATVVVEATEPEPSGSIANPAAS(0.026)T(0.213)S(0.54)PS(0.213)LS(0.008)HR;ATVVVEATEPEPS(0.001)GS(0.001)IANPAAS(0.008)T(0.252)S(0.665)PS(0.069)LS(0.003)HR;ATVVVEATEPEPSGSIANPAAS(0.019)T(0.359)S(0.451)PS(0.163)LS(0.008)HR 99.10799999999999 2.4907e-17 43368000.0 1717.16 4600.3 3221.1800000000003 4517.14 4812.71 3597.27 3606.93 3508.4 3198.0 1641.82 True False 2007.84127254405 5056.987381676451 3297.985147593179 4264.059290565474 3869.6940238278103 3408.6228285680863 3265.2554784882013 3416.308217457072 3244.764699978403 1939.468969360031 1.0352531049808855 2.607408245023436 1.7004578055618076 2.1985705148829946 1.995233790775574 1.7575031528825305 1.6835822228007298 1.761465778225034 1.6730170738689787 1.0 10.921445978237763 -9.182906906885695 0.5078000358528838 0.9440774564473748 1.9346683655915546 0.3101851314863172 0.3789789711987789 2.7672100613505166 1.142593474835422 0.6968064092700693 0.17994622733957566 6.562859292769143e-10 9.182906906885695 0.9905909091441798 (ac)AVSVT(ph)PIRDTK ddPTM_PC-9_Lapatinib_30min_R1 1 AVSVTPIRDTK 11 1 C9JP00;A0A0A0MQX8;Q9NR56-7;Q9NR56-6;Q9NR56-2;Q9NR56-5;Q9NR56;Q9NR56-3;Q9NR56-4 C9JP00 MBNL1 Muscleblind-like protein 1 1 AVS(0.001)VT(0.929)PIRDT(0.071)K 56.93600000000001 0.027669 3695900.0 27635.0 32777.0 43397.0 33771.0 40130.0 35346.0 31043.0 30298.0 37970.0 30600.0 True False 27240.919832361662 32701.10687031287 39829.06617726441 36254.63199675349 37769.63229861561 33834.333975550355 32650.254645434445 31705.755688286947 33693.41875817421 35889.16922806297 0.7590289889201741 0.9111692349998103 1.1097795528273386 1.0101830935781246 1.0523963945390589 0.9427449758044031 0.9097523110093084 0.8834352081768203 0.9388185762691929 1.0 15.13126090720537 -10.236268468793867 14.971087470847051 1.0000087344446267 0.95209958174434 0.026567228871616777 0.09166223145532773 0.0 0.0 0.09506444324240514 0.023056514160527734 5.8040551602175895e-11 10.236268468793867 -0.04790915270028673 (ac)CDFTEDQTAEFK ddPTM_PC-9_AZD4547_30min_R2 2 CDFTEDQTAEFK 12 0 F8W1R7;G3V1V0;P60660-2;P60660;G3V1Y7 F8W1R7 MYL6 Myosin light polypeptide 6 0 ; 100.48 8.6491e-07 0.0 10189.2 10461.2 13460.7 17781.6 13137.5 11442.3 11023.1 13310.5 11055.6 12501.2 False True 13429.153651474058 13842.578320084178 13282.202322934865 13682.32684298141 11313.584894756865 10726.811172167148 12004.134545425748 11253.668069861558 11639.976445545273 12063.536793069137 1.1132020303688641 1.147472632407202 1.101020583827944 1.1341886776390748 0.9378331652502488 0.8891928922809786 0.995075884571636 0.9328663942341625 0.9648892066406917 1.0 13.558365318774989 -6.2612759607018615 24.999991235415067 0.948835385594305 1.1240103628581617 0.8719628204506317 0.0320100602371964 4.674463456607246 715111.3096984082 0.009452879083318988 0.011443286062686584 5.479286877912402e-07 6.2612759607018615 0.17517497726385667 (ac)CDFTEDQTAEFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CDFTEDQTAEFK 12 0 F8W1R7;G3V1V0;P60660-2;P60660;G3V1Y7 F8W1R7 MYL6 Myosin light polypeptide 6 0 151.83 5.5296e-08 1046800.0 7831.5 8181.7 7571.1 10396.0 11658.0 9285.3 9583.7 7434.8 8412.1 7969.1 False True 9157.218270824344 8993.925105028418 7751.623737556647 9813.545824286746 9373.698587653233 8798.36252216355 8675.862556020602 7239.644377821757 8535.111048370327 9413.83474663911 0.9727404949501177 0.955394411213708 0.8234289156524764 1.0424599632780192 0.9957364708361588 0.9346204558460841 0.9216076964935065 0.7690430704029967 0.9066561372789658 1.0 13.200566812397476 -7.531508216863042 24.99649493681005 0.8717748357279181 0.9519329277084246 0.10628478724293078 0.07455470986862646 337.82431856054416 978541.166041303 0.034569016318299145 0.01999836304716135 2.9409780498387158e-08 7.531508216863042 0.0801580919805065 (ac)CDFTEDQTAEFK ddPTM_PC-9_Lapatinib_30min_R1 4 CDFTEDQTAEFK 12 0 F8W1R7;G3V1V0;P60660-2;P60660;G3V1Y7 F8W1R7 MYL6 Myosin light polypeptide 6 0 ;;; 173.37 1.1574000000000002e-11 4208700.0 64320.4 68939.0 68147.1 64334.0 73482.0 65197.0 71830.0 64508.3 67401.0 64783.8 False True 63403.179301083226 68779.37598109937 62544.308493413315 69065.3369719327 69159.93323117052 62408.67629163004 75549.00593311078 67505.59111712711 59809.58961600483 75981.59351101259 0.8344544562874129 0.9052110228660926 0.8231507869645863 0.9089745789804019 0.9102195681266759 0.821365720404175 0.9943066793164964 0.8884466355307884 0.7871589269490139 1.0 16.213362348545385 -12.067723547232625 2.290277445203004 3.148870928007197 0.8785747109150256 0.29897484598079715 0.05724902722858597 6710172.127005363 692185.437252483 74620794.87931423 0.013801327579299359 8.556111840239973e-13 12.067723547232625 -2.2702962170921714 (ac)DDDIAALVVDNGSGMCK ddPTM_PC-9_AZD4547_30min_R2 4 DDDIAALVVDNGSGMCK 17 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5 P60709 ACTB Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed 0 ;;; 136.96 6.585699999999999e-43 52769000.0 36898.700000000004 41038.3 51930.7 67551.3 60761.6 54639.2 41290.3 60367.4 47902.6 55196.0 False True 48631.719059361494 54303.12792730384 51242.06498708336 51978.39144218131 52325.900661561085 51222.60218647255 44965.056710089964 51039.00543484925 50434.63364090386 53263.60484035483 0.913038447268518 1.0195165740295786 0.9620465070035992 0.9758707019168973 0.9823950297467794 0.9616811017579507 0.844198526270653 0.9582341560963946 0.9468873500407992 1.0 15.700862451907776 -7.018193272584736 24.97994733453825 0.9294338510885223 0.9730055930407029 0.10240015242423406 0.043993779134278876 1286.4246020119392 1766297.772811024 0.0159252677709169 0.012590416662640947 9.589737677311455e-08 7.018193272584736 0.04357174195218061 (ac)DDDIAALVVDNGSGMCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 DDDIAALVVDNGSGMCK 17 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5 P60709 ACTB Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed 0 ;;;; 116.71 6.275800000000001e-18 74085000.0 118433.2 124915.8 110292.4 138624.40000000002 160748.9 136862.7 138969.9 133787.7 122241.0 107272.82 False True 138481.6015976755 137316.61508423803 112922.18910225625 130857.7242943687 129251.30699063421 129685.3790789866 125805.66501705264 130275.91463478567 124028.54336774864 126720.53309482416 1.0928110718572388 1.0836177194857985 0.8911120111667877 1.0326481517912232 1.01997130089341 1.0233967290994892 0.9927804274853632 1.0280568701309127 0.9787564835679698 1.0 16.951290784187627 -5.043543542334387 24.999557785160896 0.9990582884525948 1.0905129956875057 0.4738447279970174 0.03887036405257895 329.7579313623817 189323.05260653634 0.009614250866560028 0.02544083745266919 9.045997380849401e-06 5.043543542334387 0.09145470723491089 (ac)DDDIAALVVDNGSGMCK ddPTM_PC-9_Lapatinib_30min_R1 4 DDDIAALVVDNGSGMCK 17 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5 P60709 ACTB Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed 0 ;;; 171.67 5.865199999999999e-69 92604200.0 162070.4 163379.9 201905.6 156316.7 166550.4 161949.4 163145.5 136923.2 150370.5 152434.8 False True 159759.24637592884 163001.6038795808 185305.70094615463 167812.7515752247 156754.23292268487 155023.20168449022 171592.3757129375 143285.1517347167 133434.19081843656 178782.95207339682 0.8935932902055557 0.9117290098927485 1.0364841770264537 0.9386395605903831 0.8767851246707886 0.8671028187343479 0.9597804137527199 0.8014475098044751 0.7463473964992872 1.0 17.447849648699865 -6.255885392974282 4.433276673278491 0.868526073534072 0.9501471036070713 0.16721944322902027 0.07564650784445329 0.3495111613361667 18.116957802087914 0.023959460803425987 0.029512894696973706 5.547720937980215e-07 6.255885392974282 0.08162103007299937 (ac)DFPWT(ph)NVGK ddPTM_PC-9_Lapatinib_30min_R1 1 DFPWTNVGK 9 0 H0YJC1 H0YJC1 FRMD6 1 DFPWT(1)NVGK 63.426 0.026782999999999998 0.0 218800.0 170530.0 308580.0 173050.0 204070.0 263110.0 206170.0 218830.0 300560.0 144870.0 True False 215679.87187699435 170135.14826233205 283209.74355324736 185776.67427787752 192067.00381705677 251857.39863936635 216844.47380244263 228997.6406781908 266707.7677628878 169910.5864728587 1.26937277043327 1.001321646838699 1.666816349895225 1.0933790420854868 1.1304004524034605 1.4822937397111375 1.2762269750453783 1.3477538123545385 1.56969482184379 1.0 17.374416218519166 -6.754338318802265 24.925651022553375 1.3532430536112257 1.2358549055210588 0.05036521892947621 0.21622323004455207 493.64620949854213 1732762.1060210036 0.070041444196164 0.0686105675331738 1.760603987765437e-07 6.754338318802265 -0.11738814809016684 (ac)DSLWGPGAGS(ph)HPFGVHNSR ddPTM_PC-9_Lapatinib_30min_R1 2 DSLWGPGAGSHPFGVHNSR 19 0 Q3SYA9 Q3SYA9 POM121L1P Putative POM121-like protein 1 1 DSLWGPGAGS(0.998)HPFGVHNS(0.002)R;DSLWGPGAGS(0.988)HPFGVHNS(0.012)R 101.53 0.0019126999999999998 20769600.0 10204.8 4221.1 45036.0 8183.2 16196.1 32504.4 11849.2 16856.2 43046.0 18259.9 True False 10059.277680668873 4211.326302293611 41333.31392398737 8785.019826354952 15243.477240757733 31114.262583457206 12462.693597419127 17639.40058858348 38197.70618552455 21416.09938521264 0.4697063409975856 0.19664301264876655 1.9300113050711345 0.41020634375748277 0.7117765456058271 1.4528445177528893 0.5819310684570483 0.8236514162220927 1.7835977270398384 1.0 14.386408118738869 (ac)DYT(ph)VSMFLNT(ph)LTPK ddPTM_PC-9_Lapatinib_30min_R1 1 DYTVSMFLNTLTPK 14 0 E7EPW5;B7Z4U3 E7EPW5 ST7 2 DY(0.273)T(0.369)VS(0.369)MFLNT(0.969)LT(0.021)PK 50.791000000000004 0.03315 0.0 7629.5 7980.8 7981.7 7162.9 7282.3 8780.9 7379.6 6144.4 8172.8 6181.3 True False 7520.70193092106 7962.320947938887 7325.475436252993 7689.683560733931 6853.969431552661 8405.361376277655 7761.679579339882 6429.891255235007 7252.29320060064 7249.729468935483 1.0373769067034395 1.0982921475976175 1.0104481094973372 1.0606855874669001 0.9454103716450907 1.159403452541776 1.070616443358068 0.8869146473377498 1.0003536313563344 1.0 12.823711445154183 -7.739153599113927 24.998396406102756 0.9577255701092776 1.054651507927858 0.3307528673125236 0.05997768321175504 246.14692942045303 276108.3289863689 0.02773924765301129 0.01599945333237192 1.823250750010842e-08 7.739153599113927 0.09692593781858039 (ac)EDS(ph)TSPKQEK ddPTM_PC-9_AZD4547_30min_R2 1 EDSTSPKQEK 10 1 Q5TD94-2;Q5TD94-3;Q5TD94 Q5TD94-2 RSPH4A Radial spoke head protein 4 homolog A 1 EDS(0.832)T(0.151)S(0.017)PKQEK 78.342 0.014332 25084000.0 26980.0 20487.0 35902.0 57700.0 49147.0 35573.0 34817.0 46919.0 28008.0 43239.0 True False 35559.0787811379 27109.02210487943 35425.91602204992 44398.156456113495 42323.78738897171 33348.614686514244 37915.64555053376 39668.74664136089 29488.445700534754 41725.215770927294 0.852220369005599 0.6497035810122298 0.8490289473046533 1.0640605599228228 1.014345560759484 0.799243672449752 0.9086986094617655 0.9507139965229544 0.706729615550156 1.0 15.34863188967278 -5.5171537307895235 24.941564924279014 0.9199025936892096 0.750563024058921 0.27994820305152157 0.10848944486915352 288.72426842784364 1257852.4369735972 0.029263698013558225 0.052835424457462 3.0398088090844735e-06 5.5171537307895235 -0.16933956963028862 (ac)EDS(ph)TSPKQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDSTSPKQEK 10 1 Q5TD94-2;Q5TD94-3;Q5TD94 Q5TD94-2 RSPH4A Radial spoke head protein 4 homolog A 1 EDS(0.784)T(0.162)S(0.055)PKQEK 40.616 0.035505 14974000.0 50945.0 44384.0 40493.0 62742.0 70125.0 45525.0 42968.0 69703.0 48059.0 25614.0 True False 59568.98229038449 48790.150196362774 41458.50669055765 59226.76915230852 56384.50964652447 43137.58885781779 38897.75997861923 67873.37010643334 48761.77195630456 30257.61543968756 1.9687269279075614 1.6124915822800403 1.3701842028231472 1.9574169441860054 1.8634816004888288 1.4256770809915227 1.285552724938092 2.2431830506182875 1.6115536947550047 1.0 14.885010674807592 -6.756180048529645 24.992412775412202 1.5766647188393281 1.7364997817944117 0.0968648763627954 0.3397017873165778 490.24427564981255 2329645.686229437 0.11599552441171487 0.11271152389525653 1.7531535339215814e-07 6.756180048529645 0.15983506295508354 (ac)EEEIAALVIDNGSGMCK ddPTM_PC-9_AZD4547_30min_R2 2 EEEIAALVIDNGSGMCK 17 0 P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65 P63261 ACTG1 Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ; 74.78 1.8627e-05 6432900.0 7658.1 5585.2 8552.9 11876.0 10252.400000000001 9482.0 9378.2 10532.9 7737.6 10070.599999999999 False True 10093.216501624613 7390.506675461152 8439.48295763442 9138.171682370954 8829.031229305823 8889.089041057206 10212.841632019283 8905.28232696329 8146.593739376525 9718.031359252072 1.0386071137767368 0.7604942196883326 0.8684354521658949 0.9403315696929644 0.9085205534863936 0.9147005923781395 1.050916719083863 0.9163669057812822 0.8382967123912956 1.0 13.246448372577715 -5.764327613495041 24.429741365456678 0.9374126711797803 0.8763104507509883 0.06306354675511094 0.0826087021765016 132.81879920166972 1123451.9648280393 0.022666752201753064 0.03538140919151603 1.7205701595342867e-06 5.764327613495041 -0.06110222042879199 (ac)EEEIAALVIDNGSGMCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EEEIAALVIDNGSGMCK 17 0 P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65 P63261 ACTG1 Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ;; 76.24 2.1490999999999998e-05 6219100.0 5984.6 6967.6 6442.1 8356.1 9117.7 6447.929999999999 7532.2 6736.43 7638.1 4707.15 False True 6997.6745787620985 7659.297280735795 6595.704095800297 7887.934807841725 7331.1521369571055 6109.789199867965 6818.6954875943875 6559.605850337575 7749.79276263447 5560.5190332211 1.258457085922154 1.3774428672891197 1.1861669848434158 1.418560886261799 1.3184294655152566 1.098780377041293 1.226269606642179 1.179675100678097 1.3937175138388416 1.0 12.441003838780883 -6.72711365296155 24.90600749867677 1.1938295157679337 1.3144080235715252 0.2584889390058255 0.11055577961351873 265.6718512140531 192765.1005941362 0.034855156476603616 0.03485353065760814 1.8745038944249542e-07 6.72711365296155 0.12057850780359147 (ac)EEEIAALVIDNGSGMCK ddPTM_PC-9_Lapatinib_30min_R1 5 EEEIAALVIDNGSGMCK 17 0 P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65 P63261 ACTG1 Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ;;;; 128.08 1.7423e-17 99115100.0 104156.3 91647.4 114680.4 97502.7 122914.6 103130.9 94058.9 99299.8 100467.0 107303.2 False True 102671.01206207386 91435.19607609963 105251.82019114553 104673.37381747228 115685.00488740126 98720.23181686991 98928.80960826777 103913.63121974254 89151.34849558826 125850.41514747363 0.8158178258034529 0.7265386925339447 0.8363247754710199 0.8317284745927478 0.91922624769922 0.7844251582419326 0.7860825051100652 0.8256916045765507 0.7083913739268894 1.0 16.94135045001567 -11.914844125317464 2.4342807187942173 2.7434373833969197 0.8062558070286389 0.5225826033289112 0.05621415272570661 4877842.697598445 931823.4000153497 46768181.39923377 0.014637465728538657 1.2166225860485016e-12 11.914844125317464 -1.937181576368281 (ac)ET(ph)GQRTSR ddPTM_PC-9_Lapatinib_30min_R1 1 ETGQRTSR 8 1 Q7Z6P3 Q7Z6P3 RAB44 Ras-related protein Rab-44 1 ET(0.475)GQRT(0.475)S(0.05)R 41.427 0.039393 2768900.0 2340.2 2816.4 2844.8 2359.8 2339.0 2849.6 2150.6 2719.9 3237.2 2497.0 True False 2306.8283188598807 2809.878798839099 2610.911525245564 2533.347564062031 2201.424618650932 2727.729250742043 2261.947545033384 2846.2764834831232 2872.592446772757 2928.603122956642 0.7876889499902487 0.9594604256251418 0.8915211162547881 0.865036147849364 0.7516978321147287 0.9314096639998792 0.7723639735621739 0.9718887688030586 0.9808746102382975 1.0 11.515996980666205 -7.880130777270884 8.063716677104265 0.9855063113569307 0.8569475106793352 0.47707360007921984 0.06372141611172442 0.2168736619169021 14.252215075580166 0.03427471136337852 0.01639908635891289 1.317859837210348e-08 7.880130777270884 -0.1285588006775955 (ac)GTRDDEYDYLFK ddPTM_PC-9_AZD4547_30min_R2 1 GTRDDEYDYLFK 12 1 B4DQU5;H3BMH2;H3BSC1;P62491-2;Q15907-2;P62491;Q15907 B4DQU5 RAB11A;RAB11B Ras-related protein Rab-11A;Ras-related protein Rab-11B 0 60.518 0.0008152000000000001 7026900.0 11372.0 13484.0 11156.0 18530.0 16581.0 10598.0 10441.0 11657.0 12684.0 9701.6 False True 14988.059447705711 17842.4393060084 11008.06415079909 14258.194785646148 14279.014358893519 9935.305384636607 11370.22877310288 9855.67850121154 13354.450345100773 9361.949936937222 1.600954881052171 1.9058464770903896 1.1758302730681336 1.52299412854057 1.5252179786345794 1.0612431653193564 1.2145150155356064 1.052737791549849 1.4264603458742382 1.0 13.192593334915381 -3.4912842773195236 0.25645029556546545 1.0537597942611734 2.9948792553384798 0.48735924850665846 0.20013594196149748 15.429993085890075 0.5034203108432457 0.2581168172414581 10.599497284497485 0.0003226381529037852 3.4912842773195236 1.9411194610773064 (ac)GTRDDEYDYLFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTRDDEYDYLFK 12 1 B4DQU5;H3BMH2;H3BSC1;P62491-2;Q15907-2;P62491;Q15907 B4DQU5 RAB11A;RAB11B Ras-related protein Rab-11A;Ras-related protein Rab-11B 0 60.398 0.00084072 1662100.0 6719.7 9830.2 9178.6 8787.9 13791.0 8840.5 7961.4 5915.0 5166.9 8193.5 False True 7857.2124898752945 10806.077290471461 9397.452634034347 8295.542453756205 11088.752549521852 8376.888617189195 7207.238556455479 5759.737517460547 5242.456137685557 9678.916690289681 0.8117863539168592 1.1164552435204445 0.9709198802653491 0.8570734431549205 1.145660501515276 0.8654779129975633 0.7446327711122982 0.5950808031273759 0.5416366630105435 1.0 13.240629868008414 -7.190736243155423 2.8837575251461263 0.6796046560341575 0.9814739641869346 0.3898133547096839 0.14949218152083688 0.24086882883366653 3.9300969854953998 0.062039025056930666 0.044448929226239255 6.445606028764782e-08 7.190736243155423 0.301869308152777 (ac)GTRDDEYDYLFK ddPTM_PC-9_Lapatinib_30min_R1 1 GTRDDEYDYLFK 12 1 B4DQU5;H3BMH2;H3BSC1;P62491-2;Q15907-2;P62491;Q15907 B4DQU5 RAB11A;RAB11B Ras-related protein Rab-11A;Ras-related protein Rab-11B 0 62.463 0.017557 1471400.0 7280.2 6907.0 6559.4 6047.5 5907.2 4451.9 4205.5 3194.6 6238.2 4163.6 False True 7176.38301297483 6891.007265864818 6020.111452016225 6492.253323868611 5559.750110002045 4261.502614885776 4423.240212330465 3343.032778460672 5535.588224841783 4883.272712351733 1.46958473050725 1.4111452855038646 1.2328026318884413 1.329488174487394 1.1385295144256908 0.872673484752704 0.9057942230304558 0.6845885895343949 1.1335816266906587 1.0 12.253632633960654 -6.46858760630222 1.8789158243906532 0.8941202511170863 1.3699040557834814 0.7447752862950572 0.1211529633299997 0.1646779389648031 1.162850287223481 0.044075945432315855 0.04978632536614927 3.3994792426361895e-07 6.46858760630222 0.47578380466639514 (ac)HYIKT(ph)WS(ph)LLGEMSEK ddPTM_PC-9_AZD4547_30min_R2 1 HYIKTWSLLGEMSEK 15 1 Q6ZUJ4 Q6ZUJ4 C3orf62 Uncharacterized protein C3orf62 2 HY(0.069)IKT(0.926)WS(0.733)LLGEMS(0.272)EK 40.801 0.0076635 1844800.0 1677.7 4968.8 6141.0 4696.5 4826.5 6311.5 3852.2 5285.9 4780.0 5519.0 True False 2211.1737016721663 6574.867429820124 6059.56632754188 3613.7944852016826 4156.42378645435 5916.840907259287 4195.038337299768 4469.0856128981795 5032.661041436593 5325.78148985286 0.41518295594460375 1.2345357094253924 1.1377797491480057 0.678547268994606 0.7804345323542711 1.110980786300107 0.7876850271255997 0.8391417525133293 0.9449619837061011 1.0 12.378777522453461 (ac)IPFLS(ph)NLPSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IPFLSNLPSER 11 0 H0YMF3 H0YMF3 RASGRP1 1 IPFLS(0.859)NLPS(0.141)ER 41.383 0.034263999999999996 3068500.0 28403.0 39039.0 39450.0 31405.0 37930.0 27496.0 26613.0 29713.0 32417.0 29199.0 True False 33211.066915178926 42914.533920237154 40390.63761495815 29645.479666383733 30497.88878278325 26054.0613560584 24092.0239785653 28933.065233525824 32891.03729806124 34492.54756084317 0.9628476080694307 1.244168290107827 1.1709960693309485 0.8594749232161107 0.8841877721263256 0.7553533501722453 0.6984704141109943 0.8388207679496362 0.9535693830687063 1.0 15.07399706728309 -5.781292537825865 8.475936625675189 0.8390265426915375 1.1379834379924985 0.5758935575154387 0.10548150717904964 0.12102055964121705 42.75135311331746 0.029946771604726547 0.045802500539210915 1.6546550235702944e-06 5.781292537825865 0.2989568953009609 (ac)KSKEEETAVDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSKEEETAVDK 11 2 O75069-3 O75069-3 0 65.5 0.013854 726070.0 679.67 0.0 20863.0 4139.8 10839.0 10796.0 2348.4 5550.5 8078.2 3134.9 False True 794.7247069055971 0.0 21360.453043368092 3907.8604274126888 8715.175758412535 10229.838754728189 2125.942551056354 5404.805256240875 8196.328392547073 3703.2325541452565 0.21460297059011668 0.0 5.768056078319472 1.0552565549896076 2.3533968312784195 2.762407870733719 0.5740775174048024 1.4594830805834602 2.2132902194793083 1.0 11.854569434813659 -7.25716895726767 24.811842835807777 1.3500029953988075 2.074448603239514 0.04684704745980606 1.5645052038898322 1289.5661712418885 7492617.081764766 0.6281332069551727 0.4687793774167185 5.531348765966816e-08 7.25716895726767 0.7244456078407067 (ac)LPQY(ph)CT(ph)TIKK ddPTM_PC-9_AZD4547_30min_R2 1 LPQYCTTIKK 10 1 Q9ULH0-5 Q9ULH0-5 2 LPQY(1)CT(0.748)T(0.252)IKK 76.92699999999999 0.007008100000000001 0.0 11779.0 9892.7 10757.0 13582.0 13388.0 12403.0 12379.0 13199.0 10779.0 9231.2 True False 15524.476981579806 13090.321812707609 10614.355151501055 10450.879739808204 11529.307293701619 11627.438449296831 13480.707018699399 11159.397832846456 11348.755934235363 8908.018497758603 1.7427531145659394 1.4694987236500843 1.1915506410512946 1.1731991511285937 1.2942617144994224 1.3052777620772202 1.513322746477385 1.2527362662812538 1.2739933058166513 1.0 13.120888838588968 -1.5228787452803376 0.03242840454834073 1.3499923306413686e-10 3.295682174858336 0.4173718923703019 0.1500398092125614 1467.3422488466879 3.656816477231732 114.31908097433217 297.023300268322 0.029999999999999995 1.5228787452803376 3.295682174723337 (ac)MAASALR ddPTM_PC-9_Lapatinib_30min_R1 1 MAASALR 7 0 F8WDQ2;Q8WWH4-2;Q8WWH4 F8WDQ2 ASZ1 Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 0 46.766000000000005 0.036819 1453100.0 3045.4 3853.4 4074.4 2436.9 2784.1 4153.2 3206.3 2464.6 3322.1 2799.9 False True 3001.9720375420397 3844.4776890521903 3739.418559638826 2616.117755260094 2620.344711751201 3975.5773175820673 3372.3065254536127 2579.114313464651 2947.930114736121 3283.8589843677623 0.914159850295766 1.170719481973238 1.1387268994922364 0.7966595909610206 0.7979467828018483 1.2106419113936102 1.026934025336316 0.7853913111805575 0.8977030161067293 1.0 11.681176460827325 -5.740920482098071 24.998576578322684 0.931947627313972 1.08415383876038 0.18530459947846933 0.13769692435444641 422.14313077670823 514301.2602300597 0.03961692984579129 0.06851770839599923 1.8158481081983424e-06 5.740920482098071 0.152206211446408 (ac)MAEPGHS(ph)HHLSARVRGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MAEPGHSHHLSARVRGR 17 2 E9PIF6;E9PMS2;E9PS21;E9PLY8;E9PLQ2;E9PB18;Q6UXG2-3;Q6UXG2-2;Q6UXG2-4;Q6UXG2 E9PIF6 KIAA1324 UPF0577 protein KIAA1324 1 MAEPGHS(0.5)HHLS(0.5)ARVRGR 81.632 0.01846 4086800.0 6708.3 7320.9 6929.7 6649.7 15091.0 10014.0 11617.0 11470.0 11712.0 8664.5 True False 7843.882695035557 8047.670569857435 7094.9303290336 6277.138867618273 12134.026881649941 9488.848211360513 10516.5536602034 11168.924653469567 11883.265843072873 10235.30526185574 0.7663555208526727 0.7862658087833455 0.6931820935008669 0.6132830147246805 1.1855070827120546 0.9270703675759361 1.027478261874201 1.0912155883706935 1.1610074676872262 1.0 13.321266510068863 -6.2594787445917754 24.99999885555862 1.061130028828797 0.7183362238345004 0.8130927367334728 0.08232912236478301 77.15725779353085 983829.297844664 0.025489499586601325 0.03127833505028991 5.502008479941099e-07 6.2594787445917754 -0.3427938049942967 (ac)MAESSS(ph)ESDHFR ddPTM_PC-9_Lapatinib_30min_R1 1 MAESSSESDHFR 12 0 Q6ZU80;G3V3U2;G3V3F4;Q86TS1;Q6ZU80-3;Q6ZU80-1 Q6ZU80 CEP128 Centrosomal protein of 128 kDa 1 MAES(0.001)S(0.034)S(0.935)ES(0.03)DHFR 44.543 0.037892 0.0 13568.0 11662.0 13823.0 10639.0 13346.0 12754.0 12251.0 10291.0 13164.0 9906.0 True False 13374.517831933528 11634.997355511146 12686.526298323057 11421.427550663599 12561.014519245544 12208.541151026118 12885.296835396615 10769.157429142544 11681.331696934569 11618.238901084698 1.1511656754351007 1.0014424263925992 1.091949167712382 0.9830601391401304 1.0811461725126712 1.0508082382336197 1.1090576588327532 0.926918229245322 1.0054304956531734 1.0 13.504103780372407 -7.761144147843143 24.999999999586187 0.9746307736649743 1.0620882523757194 0.3964916587807664 0.050314127283353875 7.812588318426103 661773.6713776557 0.02378486362305609 0.01261507124498032 1.7332286217242313e-08 7.761144147843143 0.08745747871074505 (ac)MAHAT(ph)LSAAPSNPRLLR ddPTM_PC-9_AZD4547_30min_R2 1 MAHATLSAAPSNPRLLR 17 1 P19876 P19876 CXCL3 C-X-C motif chemokine 3;GRO-gamma(5-73) 1 MAHAT(0.978)LS(0.017)AAPS(0.005)NPRLLR 44.614 0.039386000000000004 0.0 1229.5 1190.6 2257.8 2279.1 2784.0 2935.6 1114.2 1228.2 1241.2 1186.8 True False 1620.4554248113056 1575.438166548027 2227.860096779686 1753.6887067439898 2397.4896553380117 2752.0364679316126 1213.3616415085928 1038.409911228276 1306.8072980399793 1145.2504932338056 1.414935365131937 1.3756275817873824 1.9453037653700997 1.5312708591743607 2.093419447974478 2.4029995919589426 1.0594727080906676 0.9067098572436784 1.141066784743302 1.0 10.16144746885467 -7.391448367445644 9.210084766009135 1.011466668863915 1.7829989948476082 0.6108346480478466 0.3000072961449623 0.2534526020887067 17.631820107429068 0.13587895504819 0.0914400179097757 4.060239318975345e-08 7.391448367445644 0.7715323259836933 (ac)MARQPEEEETAVARARR ddPTM_PC-9_Lapatinib_30min_R1 1 MARQPEEEETAVARARR 17 3 Q5VU97 Q5VU97 CACHD1 VWFA and cache domain-containing protein 1 0 56.872 0.0007261 1763000.0 3656.3 6722.6 7526.0 7492.9 7671.1 7846.4 5530.1 6886.2 7382.7 7211.8 False True 3604.1604915167013 6707.034232735309 6907.241331200128 8043.95286158166 7219.900979962876 7510.827762851761 5816.421519012886 7206.157991309043 6551.182582722485 8458.350020880542 0.4261068036460256 0.7929482956106237 0.8166180536568836 0.9510073290563894 0.8535826682674053 0.8879778850851882 0.6876543894086069 0.8519578846370393 0.7745225211241005 1.0 13.046160547433637 -4.734318816766564 3.107833406582151 0.8453678271069762 0.3326034877470392 0.7042147388639788 0.08235993104159292 0.2470528744129019 3.1828414732884114 0.020673139798409953 0.33280996391708184 1.8436614853398932e-05 4.734318816766564 -0.512764339359937 down (ac)MDDREDLVYQAK ddPTM_PC-9_AZD4547_30min_R2 1 MDDREDLVYQAK 12 1 I3L3T1;B4DJF2;I3L0W5;P62258 I3L3T1;P62258 YWHAE 14-3-3 protein epsilon 0 60.518 0.021289 4623300.0 19763.0 20801.0 22740.0 38403.0 33470.0 28377.0 21649.0 36345.0 24218.0 25392.0 False True 26047.222904063317 27524.516464274744 22438.45274194795 29549.781670435455 28823.268234254036 26602.58170407936 23575.719060329848 30728.71537501359 25498.11403797308 24503.033808723292 1.0630203226014519 1.123310553262012 0.9157418186298084 1.205964204314793 1.1763142661947723 1.0856852221543525 0.9621551047257131 1.2540779894803844 1.0406104908076945 1.0 14.580672765096947 -5.779168903338277 24.99955582249087 1.1105272283971637 1.0429527444883282 0.0899394355312162 0.09839804515088743 596.7009823564201 841378.1457987757 0.02739016474111523 0.040722667231378046 1.662765851171762e-06 5.779168903338277 -0.06757448390883547 (ac)MDDREDLVYQAK ddPTM_PC-9_Lapatinib_30min_R1 2 MDDREDLVYQAK 12 1 I3L3T1;B4DJF2;I3L0W5;P62258 I3L3T1;P62258 YWHAE 14-3-3 protein epsilon 0 ; 81.95 0.020849 30819100.0 87756.0 88722.0 116661.0 87170.0 105439.0 100370.0 95729.0 94150.0 112183.0 79643.0 False True 86504.58334752041 88516.56966006337 107069.58290448299 93580.77259059562 99237.28532104986 96077.40907389775 100685.37921440566 98524.55271147325 99547.76920063882 93409.18643237339 0.9260821836848799 0.9476216744928809 1.1462425377401129 1.0018369302289818 1.062393208968755 1.0285648847124487 1.0778959014625409 1.0547629893212196 1.0657171205822422 1.0 16.51127681994162 -5.103490396882083 7.98941816469117 1.054820567466278 0.931416925450395 0.5894238404664882 0.039505751134327076 0.16071986068854852 10.883047315066912 0.009262167563770862 0.024831048491565092 7.879698548451034e-06 5.103490396882083 -0.12340364201588305 (ac)MDEHSCPLIFS(ph)S(ph)YGY(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MDEHSCPLIFSSYGYPK 17 0 A0A0A0MR73 A0A0A0MR73 GABRG3 3 MDEHS(0.011)CPLIFS(0.686)S(0.686)Y(0.648)GY(0.97)PK 42.041000000000004 0.042622 0.0 477.03 440.61 593.73 0.0 745.95 765.6 882.01 687.6 0.0 413.02 True False 557.7817572280321 484.35084890995404 607.886774933564 0.0 599.7864523468799 725.4505882382275 798.4596276005849 669.5512285724211 0.0 487.89725653547896 1.1432361009545282 0.9927312408954547 1.2459319391343198 0.0 1.229329421948214 1.4868921243574857 1.636532316804537 1.3723201342160707 0.0 1.0 8.9304335607333 (ac)MDEPS(ph)PLAQPLELNQHSR ddPTM_PC-9_Lapatinib_30min_R1 2 MDEPSPLAQPLELNQHSR 18 0 A0A0C4DGT1;Q13085;A0A087X2F8;A0A087X126 A0A0C4DGT1 ACACA Acetyl-CoA carboxylase 1;Biotin carboxylase 1 MDEPS(1)PLAQPLELNQHSR;MDEPS(1)PLAQPLELNQHSR 120.59 0.00052628 2749200.0 3000.7 4304.25 3071.0600000000004 2217.9 3088.0299999999997 4513.2 3127.02 2766.42 2722.8 3556.7999999999997 True False 2957.909467739015 4294.283773577329 2818.569301434422 2381.0117646975104 2906.3981467005715 4320.180956783053 3288.9217949736308 2894.957972512731 2416.129591644897 4171.588140861909 0.7090607624385156 1.0294122115061124 0.6756585756455012 0.5707686579542246 0.6967126304324157 1.0356202028828385 0.7884099973239672 0.6939702278266118 0.5791869930730243 1.0 12.026381012877621 -10.94506474417044 4.617324542543181 1.0005163572700766 0.7596162729652336 0.18753749028113975 0.15358589425920183 0.0008586500074032699 0.0001074519654318335 0.15640815825137608 0.03785439304866091 1.1348416220503008e-11 10.94506474417044 -0.240900084304843 (ac)MDHTEGSPAEEPPAHAPSPGK ddPTM_PC-9_AZD4547_30min_R2 1 MDHTEGSPAEEPPAHAPSPGK 21 0 D6R946;Q06330 D6R946 RBPJ Recombining binding protein suppressor of hairless 0 57.61600000000001 0.0035293 32200000.0 21121.0 17567.0 133860.0 164670.0 231140.0 57587.0 25630.0 124790.0 29387.0 41004.0 False True 27837.038655908585 23245.189208591626 132084.9289374297 126707.87562613879 199050.2007668207 53986.07578647561 27911.020348110967 105506.57288892404 30940.336825250433 39568.462440646275 0.7035158037203206 0.5874675884477446 3.33813650544447 3.202244105800267 5.030526547889021 1.3643713315233346 0.7053855173164291 2.6664309498299725 0.7819443798621628 1.0 15.27206338541219 (ac)MDLAAAAEPGAGS(ph)QHLEVR ddPTM_PC-9_AZD4547_30min_R2 5 MDLAAAAEPGAGSQHLEVR 19 0 Q14566 Q14566 MCM6 DNA replication licensing factor MCM6 1 MDLAAAAEPGAGS(1)QHLEVR;MDLAAAAEPGAGS(1)QHLEVR;MDLAAAAEPGAGS(1)QHLEVR;MDLAAAAEPGAGS(1)QHLEVR;MDLAAAAEPGAGS(1)QHLEVR 99.01100000000001 6.3069e-05 41696600.0 1254.15 3311.39 4050.1000000000004 3816.3 4472.49 4215.0 3173.43 4116.09 4080.1 3311.6 True False 1652.9436120594557 4381.732059739187 3996.393027711673 2936.5109962472447 3851.5619642969446 3951.4353836802493 3455.8591222514924 3480.0428688386187 4295.7657563107605 3195.6618919725906 0.5172460879580539 1.371150080284141 1.250568164845754 0.9189054084925801 1.2052470175183287 1.2364998292235294 1.0814220149298366 1.0889896949299878 1.3442491419701186 1.0 11.641899060707084 -4.749962771523955 24.992290134700514 1.1647726874905135 0.517244660562244 0.66706991910314 0.13756400284992204 309.97472505493744 674980.6939487074 0.03378729969857866 0.5237362328897865 1.7784318537672226e-05 4.749962771523955 -0.6475280269282695 (ac)MDLAAAAEPGAGS(ph)QHLEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 MDLAAAAEPGAGSQHLEVR 19 0 Q14566 Q14566 MCM6 DNA replication licensing factor MCM6 1 MDLAAAAEPGAGS(1)QHLEVR;MDLAAAAEPGAGS(1)QHLEVR;MDLAAAAEPGAGS(1)QHLEVR;MDLAAAAEPGAGS(1)QHLEVR 156.08 1.8065e-14 61972100.0 0.0 777.4 0.0 1268.2 1101.7 0.0 975.99 980.16 0.0 0.0 True False 0.0 854.5751343423856 0.0 1197.1468655598744 885.8297936196228 0.0 883.5371616443072 954.4318385653639 0.0 0.0 0.0 (ac)MDLAAAAEPGAGS(ph)QHLEVR ddPTM_PC-9_Lapatinib_30min_R1 7 MDLAAAAEPGAGSQHLEVR 19 0 Q14566 Q14566 MCM6 DNA replication licensing factor MCM6 1 MDLAAAAEPGAGS(1)QHLEVR;MDLAAAAEPGAGS(1)QHLEVR;MDLAAAAEPGAGS(1)QHLEVR;MDLAAAAEPGAGS(1)QHLEVR;MDLAAAAEPGAGS(1)QHLEVR;MDLAAAAEPGAGS(1)QHLEVR;MDLAAAAEPGAGS(1)QHLEVR 129.06 7.0678e-11 32955300.0 1043.48 1466.0700000000002 3069.08 1081.04 1238.6999999999998 4165.32 3202.69 2059.88 2555.79 1877.92 True False 1028.5997838492044 1462.6754049900728 2816.7520893914007 1160.5432878437232 1165.8421013779002 3987.178973435165 3368.5096173174784 2155.5895447616494 2267.9300165381637 2202.5159698288903 0.4670112716272902 0.6640929850346128 1.2788793034768458 0.5269170819832393 0.5293228822619944 1.8102837972815797 1.5293916881697671 0.9786941726143822 1.029699692354265 1.0 11.104936764424991 -6.737508781727195 24.999763486487794 1.2845186792365275 0.7149199216882672 0.4459096789432322 0.3205758315898683 238.8646744754584 249536.0434157393 0.11239417471834508 0.11233777237734563 1.8301690986839503e-07 6.737508781727195 -0.5695987575482603 (ac)MDLFGDLPEPERS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 MDLFGDLPEPERSPR 15 1 F8SNU6;E9PC05;F8SNU7;Q9H0C8 F8SNU6 ILKAP2;ILKAP;ILKAP3 Integrin-linked kinase-associated serine/threonine phosphatase 2C 1 MDLFGDLPEPERS(1)PR;MDLFGDLPEPERS(1)PR 77.068 0.018631 8636600.0 1349.1 1423.73 3424.8999999999996 7920.3 3356.6099999999997 2007.95 3885.92 2672.9 1865.58 4260.07 True False 1778.085736976766 1883.9228799424018 3379.483588210092 6094.397202415179 2890.602640806077 1882.3925690772862 4231.759351975472 2259.864722131622 1964.1907501429448 4110.926245964392 0.432526790944565 0.4582721185503652 0.8220735148259247 1.4824876044414363 0.7031511800153845 0.4578998640331216 1.0293931583252556 0.5497215437397064 0.47779761363297346 1.0 12.00524777343674 -1.5228801909632204 0.03169457827589614 1.2494211160116178 7.326502823483166e-14 0.03204700522619164 0.32169797636513126 8703.617103288798 21.209488294792024 260.05442992519045 661.3450240337979 0.02999990013593056 1.5228801909632204 -1.2494211160115445 (ac)MDLFGDLPEPERS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 MDLFGDLPEPERSPR 15 1 F8SNU6;E9PC05;F8SNU7;Q9H0C8 F8SNU6 ILKAP2;ILKAP;ILKAP3 Integrin-linked kinase-associated serine/threonine phosphatase 2C 1 MDLFGDLPEPERS(1)PR;MDLFGDLPEPERS(1)PR;MDLFGDLPEPERS(1)PR;MDLFGDLPEPERS(1)PR;MDLFGDLPEPERS(1)PR 106.3 9.4752e-05 16572000.0 5417.87 7284.41 7845.5 12856.2 11808.310000000001 9858.28 7792.070000000001 7508.82 8653.699999999999 5710.63 True False 6335.008383189818 8007.5580838114365 8032.566474224435 12135.908794362771 9494.556422162601 9341.294442289904 7053.948719898517 7311.721431252428 8780.243991308032 6745.922013677789 0.9390871063058812 1.1870220360649884 1.1907292224751327 1.7989992724132353 1.4074512576504412 1.384732053431663 1.045661172126832 1.0838728073682804 1.3015632219740347 1.0 12.719799924819098 -7.258755749256456 24.696092429452715 1.1147636999721047 1.3321938493156729 0.18033285430852108 0.21811589671867923 386.2083652741287 3554110.325924651 0.09303748075956227 0.06868573144683619 5.5111756225435906e-08 7.258755749256456 0.2174301493435682 (ac)MDLFGDLPEPERS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 MDLFGDLPEPERSPR 15 1 F8SNU6;E9PC05;F8SNU7;Q9H0C8 F8SNU6 ILKAP2;ILKAP;ILKAP3 Integrin-linked kinase-associated serine/threonine phosphatase 2C 1 MDLFGDLPEPERS(1)PR;MDLFGDLPEPERS(1)PR 71.354 0.0059739 2191600.0 5713.4 4916.219999999999 9701.3 2280.44 5863.700000000001 7137.849999999999 4875.98 3980.35 6655.55 3469.6000000000004 True False 5631.925868290762 4904.836794641655 8903.696562100953 2448.151164924834 5518.808694477757 6832.580794641036 5128.434386046628 4165.291591982075 5905.931872951444 4069.3157370486047 1.3839982523389762 1.2053222486488693 2.188008288724883 0.6016124879757869 1.3562006615098492 1.6790490677424244 1.2602694697183123 1.0235852563760708 1.4513329155517682 1.0 11.990570507713734 -13.897984916218215 0.11541904911971303 3.7834154647574366e-07 1.5420962738402997 0.07595814989371752 0.3878360825324165 381.7226868709518 3.3252149771346873 92.03292297772303 4.3360879523615745 1.2647802746661024e-14 13.897984916218215 1.5420958954987531 (ac)MDLFGDLPEPERS(ph)PRPAAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MDLFGDLPEPERSPRPAAGK 20 2 F8SNU6;E9PC05;F8SNU7;Q9H0C8 F8SNU6 ILKAP2;ILKAP;ILKAP3 Integrin-linked kinase-associated serine/threonine phosphatase 2C 1 MDLFGDLPEPERS(1)PRPAAGK;MDLFGDLPEPERS(1)PRPAAGK 42.708 0.011918999999999999 191559000.0 36104.6 37476.0 41057.0 51463.0 55324.0 54801.0 52659.0 50897.0 47530.0 35508.0 True False 42216.395681645205 41196.36960974429 42035.954589539586 48579.69495529716 44483.65934665703 51927.13908835306 47670.75830185512 49561.00767982914 48225.03633207423 41945.31931882666 1.0064626129260834 0.9821446177727341 1.0021607958214362 1.158167245933749 1.0605154536680583 1.2379721964602182 1.1364976849862403 1.181562293115844 1.1497119849181598 1.0 15.356222208753875 -5.755585937029593 24.275082445195743 1.1412428485145878 0.995444792952301 0.49724411527287815 0.061784099938028844 72.16851547379468 299287.1703777262 0.016034629930457966 0.026829882402176663 1.755553475604523e-06 5.755585937029593 -0.14579805556228675 (ac)MDLFGDLPEPERS(ph)PRPAAGK ddPTM_PC-9_Lapatinib_30min_R1 1 MDLFGDLPEPERSPRPAAGK 20 2 F8SNU6;E9PC05;F8SNU7;Q9H0C8 F8SNU6 ILKAP2;ILKAP;ILKAP3 Integrin-linked kinase-associated serine/threonine phosphatase 2C 1 MDLFGDLPEPERS(1)PRPAAGK 62.203 0.00045698 0.0 8466.6 6551.5 8496.3 6842.9 6584.1 6433.7 7083.8 5834.7 6719.2 6401.2 True False 8345.864731415713 6536.330404272958 7797.76701066644 7346.149693245227 6196.83618283865 6158.545648687211 7450.564502700405 6105.801462619568 5962.4129396872295 7507.6388909371435 1.1116497280510436 0.8706239736920882 1.038644389260587 0.9784900152980376 0.8254041347565569 0.8203039248626499 0.9923978245270113 0.8132785222249028 0.7941795052083238 1.0 12.87414354447618 -6.174611426037513 6.032525809462603 0.8683579035172306 0.9950828179011824 0.33011573664076554 0.08746944976549842 0.28186158507475684 15.823231996201864 0.025162655370247297 0.03264312727488416 6.689421689171713e-07 6.174611426037513 0.12672491438395173 (ac)MDNYADLS(ph)DTELTTLLR ddPTM_PC-9_AZD4547_30min_R2 2 MDNYADLSDTELTTLLR 17 0 P50402;Q5HY57;F8WEQ1 P50402 EMD Emerin 1 MDNY(0.001)ADLS(0.913)DT(0.085)ELT(0.001)TLLR;MDNY(0.031)ADLS(0.877)DT(0.088)ELTT(0.003)LLR 131.18 6.656e-05 1170930.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)MDNYADLS(ph)DTELTTLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MDNYADLSDTELTTLLR 17 0 P50402;Q5HY57;F8WEQ1 P50402 EMD Emerin 1 MDNY(0.001)ADLS(0.98)DT(0.019)ELTTLLR;MDNYADLS(0.906)DT(0.092)ELTT(0.002)LLR 193.3 8.082200000000001e-23 2105740.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 467.13 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 454.8683324651472 0.0 0.0 0.0 (ac)MDNYADLS(ph)DTELTTLLR ddPTM_PC-9_Lapatinib_30min_R1 2 MDNYADLSDTELTTLLR 17 0 P50402;Q5HY57;F8WEQ1 P50402 EMD Emerin 1 MDNYADLS(0.983)DT(0.016)ELTT(0.001)LLR;MDNYADLS(0.928)DT(0.071)ELTT(0.001)LLR 148.33 6.6715e-25 428500.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)MDRNPS(ph)PPPPGR ddPTM_PC-9_AZD4547_30min_R2 1 MDRNPSPPPPGR 12 1 J3KND1;E9PRZ1;Q96ER3;E9PL53;E9PMD2 J3KND1 SAAL1 Protein SAAL1 1 MDRNPS(1)PPPPGR 85.355 0.030802999999999997 80646000.0 0.0 0.0 5845.4 11514.0 10844.0 7148.2 0.0 6194.2 1623.3 4878.9 True False 0.0 0.0 5767.886176683488 8859.625189526705 9338.497781065154 6701.221923991262 0.0 5237.028718555759 1709.104323967367 4708.0911960215835 0.0 0.0 1.2251007757788228 1.8817870811451651 1.9834997650335113 1.4233415719843974 0.0 1.1123464904378098 0.3630142775083858 1.0 12.200926550402471 -5.259362457572628 24.999998365035935 1.1560087599913051 7.442893688072765e-05 0.3802215857550838 0.5726410529895406 196.51973819270094 2365474.8028660957 0.16371053006724298 0.39136188565901775 5.5034818991487115e-06 5.259362457572628 -1.1559343310544243 (ac)MDRNPS(ph)PPPPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 MDRNPSPPPPGR 12 1 J3KND1;E9PRZ1;Q96ER3;E9PL53;E9PMD2 J3KND1 SAAL1 Protein SAAL1 1 MDRNPS(1)PPPPGR;MDRNPS(1)PPPPGR;MDRNPS(1)PPPPGR 87.806 0.00063823 278615000.0 7395.799999999999 7839.799999999999 23063.2 16198.8 22276.2 13144.0 8605.8 16707.5 15381.5 6412.599999999999 True False 8647.762866291601 8618.083532566801 23613.114155673058 15291.233753218175 17911.338521039714 12454.705501310418 7790.596323403492 16268.945828059534 15606.425338560912 7575.153617886333 1.1415957091447808 1.1376777247418346 3.117179577707592 2.018603783441798 2.3644851873033628 1.6441522019966122 1.0284407044905939 2.1476720669592173 2.060212389846625 1.0 12.887059430213434 -6.960340622082493 24.819856148551047 1.6092310884944454 1.981036591700159 0.08009132043381728 0.6369429321861965 446.64477029069604 279520.33422468713 0.236800393255863 0.208838033735641 1.0956185530293927e-07 6.960340622082493 0.3718055032057137 (ac)MDRNPS(ph)PPPPGR ddPTM_PC-9_Lapatinib_30min_R1 3 MDRNPSPPPPGR 12 1 J3KND1;E9PRZ1;Q96ER3;E9PL53;E9PMD2 J3KND1 SAAL1 Protein SAAL1 1 MDRNPS(1)PPPPGR;MDRNPS(1)PPPPGR;MDRNPS(1)PPPPGR 77.597 0.0028623 181588000.0 6735.5 10896.1 12249.8 6141.6 8701.3 4171.7 10190.08 7031.299999999999 9963.5 4241.4 True False 6639.450534860576 10870.870749904392 11242.668729595438 6593.27375177701 8189.506641413997 3993.2861157076727 10717.672481955626 7357.999867022638 8841.305709693672 4974.520338689749 1.3346916049818296 2.185310343462722 2.2600508117646316 1.3254089445563768 1.6462907142462404 0.8027479724325489 2.154513752531682 1.4791375582074067 1.7773182352737962 1.0 12.280341707131369 -5.772824860303226 24.997250779659076 1.4849558782549386 1.9525469072551913 0.2016685497367562 0.4261894472893005 333.8570764357062 732995.7650169211 0.11717446818975687 0.17552458296565046 1.6872333056266997e-06 5.772824860303226 0.46759102900025273 (ac)MDS(ph)AGQDINLNSPNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MDSAGQDINLNSPNK 15 0 A0A087WYR3;O43399;O43399-5;O43399-7;O43399-2;O43399-4;O43399-3;A0A087WZ51 A0A087WYR3 TPD52L2 Tumor protein D54 1 MDS(0.862)AGQDINLNS(0.138)PNK 166.86 4.6225e-24 8558200.0 48466.0 77850.0 44787.0 38592.0 47253.0 29880.0 47341.0 31632.0 33849.0 26657.0 True False 56670.33655286634 85578.4335072737 45854.891935643354 36429.81535695211 37994.11385849872 28313.040199266237 42856.51776084093 30801.693516874377 34343.97758898342 31489.703083304095 1.7996465829782011 2.7176640338869236 1.4561868625543095 1.1568802430616525 1.2065567515193014 0.8991205831431884 1.3609692554885835 0.978151284417969 1.0906415185347578 1.0 14.942592533902282 -5.453820758492212 4.506919575205088 1.1147798185616216 2.2511569154007915 0.7822886996725652 0.24112355319776316 0.08495967183371962 3.2926584223008573 0.05991350211440204 0.12750325026909526 3.5170556608580014e-06 5.453820758492212 1.13637709683917 (ac)MDS(ph)AGQDINLNSPNKGLLSDSMTDVPVDTGVAAR ddPTM_PC-9_AZD4547_30min_R2 1 MDSAGQDINLNSPNKGLLSDSMTDVPVDTGVAAR 34 1 A0A087WYR3;O43399;O43399-5;O43399-7;O43399-2;O43399-4;O43399-3;A0A087WZ51 A0A087WYR3 TPD52L2 Tumor protein D54 1 MDS(0.93)AGQDINLNS(0.042)PNKGLLS(0.012)DS(0.013)MT(0.003)DVPVDTGVAAR 51.236000000000004 0.00092446 0.0 868.55 0.0 1202.7 1643.9 1139.3 1439.4 0.0 1647.9 0.0 1150.3 True False 1144.7308330377061 0.0 1186.7514121697807 1264.9242530018198 981.127860749496 1349.3940904553629 0.0 1393.2549199748216 0.0 1110.0283471240707 1.0312627024377754 0.0 1.069118113284664 1.1395422975269622 0.8838764012571949 1.2156393068262226 0.0 1.2551525585671317 0.0 1.0 10.116380804240285 -10.685759789980517 4.722333708401668 1.0000213747365694 0.745503024046529 0.0244276553144962 0.5008886612237136 0.00014139375682832873 2.5064018284956915e-05 0.4587134478799186 0.11124197172239386 2.061769971194496e-11 10.685759789980517 -0.25451835069004036 (ac)MDS(ph)AGQDINLNSPNKGLLSDSMTDVPVDTGVAAR ddPTM_PC-9_Lapatinib_30min_R1 2 MDSAGQDINLNSPNKGLLSDSMTDVPVDTGVAAR 34 1 A0A087WYR3;O43399;O43399-5;O43399-7;O43399-2;O43399-4;O43399-3;A0A087WZ51 A0A087WYR3 TPD52L2 Tumor protein D54 1 MDS(0.772)AGQDINLNS(0.201)PNKGLLS(0.012)DS(0.013)MT(0.002)DVPVDTGVAAR;MDS(0.844)AGQDINLNS(0.152)PNKGLLS(0.001)DS(0.002)MT(0.001)DVPVDTGVAAR 50.583 4.7862e-12 30688600.0 7597.2 0.0 5047.110000000001 4573.93 4758.86 4731.150000000001 3175.8599999999997 2859.43 4898.98 3183.56 True False 7488.862534844153 0.0 4632.156098208007 4910.312070383187 4478.953211078737 4528.809743349317 3340.2904911976743 2992.289556662431 4347.205283853579 3733.8341041729445 2.005676290351137 0.0 1.2405896911785919 1.3150857626200927 1.1995587072476104 1.2129113444777595 0.8946006699827813 0.8013986356057542 1.1642738168241404 1.0 11.866442114099838 -7.269489697155524 23.61215355505343 0.9485181694360815 1.1216681603061716 0.03641611835291292 0.46683047849571396 1338.785030968287 3926719.5094681173 0.18672888160997675 0.12855848691042038 5.3766318804945616e-08 7.269489697155524 0.1731499908700901 (ac)MDSAGQDINLNS(ph)PNK ddPTM_PC-9_AZD4547_30min_R2 6 MDSAGQDINLNSPNK 15 0 A0A087WYR3;O43399;O43399-5;O43399-7;O43399-2;O43399-4;O43399-3;A0A087WZ51 A0A087WYR3 TPD52L2 Tumor protein D54 1 MDSAGQDINLNS(1)PNK;MDSAGQDINLNS(1)PNK;MDSAGQDINLNS(1)PNK;MDSAGQDINLNS(1)PNK;MDSAGQDINLNS(1)PNK;MDSAGQDINLNS(1)PNK 215.37 4.493199999999999e-148 26499600.0 219748.0 271081.0 200119.0 174786.0 174925.0 241614.0 247352.0 263891.0 252105.0 198177.0 True False 289623.2929576531 358702.63197211956 197465.29130456824 134491.78811678078 150639.68317528808 226505.83838493962 269365.8488156832 223112.7095619129 265430.755617442 191238.88355038388 1.5144581874812548 1.8756783417302036 1.0325582728710292 0.7032659133954184 0.7877042596078557 1.184413097272994 1.408530753865837 1.16667021590895 1.3879539071221962 1.0 17.54501636282852 -5.269085875953318 24.858900334018056 1.0808526067682276 1.695068271498544 0.5335733859292366 0.22855871009119613 400.4965690965521 1302024.9194034713 0.06673490476019335 0.14329263865672523 5.381633573536158e-06 5.269085875953318 0.6142156647303165 (ac)MDSAGQDINLNS(ph)PNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 MDSAGQDINLNSPNK 15 0 A0A087WYR3;O43399;O43399-5;O43399-7;O43399-2;O43399-4;O43399-3;A0A087WZ51 A0A087WYR3 TPD52L2 Tumor protein D54 1 MDSAGQDINLNS(1)PNK;MDSAGQDINLNS(1)PNK;MDSAGQDINLNS(1)PNK 204.23 1.2952999999999997e-103 22219100.0 123339.0 190317.0 121532.0 108783.0 131850.0 79770.0 142258.0 94153.0 80467.0 74834.0 True False 144217.8566437089 209210.41399876462 124429.78379267664 102688.24118924463 106014.93899314431 75586.72077294077 128782.29238127012 91681.58351334972 81643.67764639226 88400.81181438208 1.6314087357764042 2.366611908927377 1.4075638134856239 1.16162102000672 1.1992530025148092 0.8550455501659029 1.456799883825482 1.0371124612051796 0.9235625326362615 1.0 16.431771997980697 -5.474469550279322 4.170750240870939 1.1090936625224608 1.9959034669879774 0.7094835145774768 0.22941191206695263 0.10611978437437833 3.8633863469967795 0.05899319259708119 0.12445648058491617 3.353748177853098e-06 5.474469550279322 0.8868098044655166 (ac)MDSAGQDINLNS(ph)PNK ddPTM_PC-9_Lapatinib_30min_R1 8 MDSAGQDINLNSPNK 15 0 A0A087WYR3;O43399;O43399-5;O43399-7;O43399-2;O43399-4;O43399-3;A0A087WZ51 A0A087WYR3 TPD52L2 Tumor protein D54 1 MDSAGQDINLNS(1)PNK;MDS(0.076)AGQDINLNS(0.924)PNK;MDSAGQDINLNS(1)PNK;MDSAGQDINLNS(1)PNK;MDSAGQDINLNS(1)PNK;MDSAGQDINLNS(1)PNK;MDSAGQDINLNS(1)PNK;MDSAGQDINLNS(1)PNK 214.65 8.758699999999998e-76 46650800.0 145539.9 293181.9 238180.6 226192.6 305726.8 267851.7 310451.0 307294.9 252642.6 253488.3 True False 143464.47433725122 292503.05532359227 218598.31047170438 242827.55836039432 287744.55070601555 256396.3071838091 326524.63373159076 321572.9428891862 224187.32994347948 297303.41490307136 0.482552393096542 0.9838536682094818 0.7352700961843076 0.8167667984559223 0.9678481183938898 0.8624061962672073 1.0982875317394059 1.0816321870841186 0.7540691384812057 1.0 18.18157650894181 -4.053025633281587 0.55681563119805 0.9698131715005587 2.1077878862706655e-17 0.43030768807624453 0.13507304033500941 8.734150337244234 1.12779696670234 0.06948855175169895 6.541700973488205 8.850633693602439e-05 4.053025633281587 -0.9698131715005587 (ac)MDSAGQDINLNS(ph)PNKGLLSDSMTDVPVDTGVAAR ddPTM_PC-9_AZD4547_30min_R2 2 MDSAGQDINLNSPNKGLLSDSMTDVPVDTGVAAR 34 1 A0A087WYR3;O43399;O43399-5;O43399-7;O43399-2;O43399-4;O43399-3;A0A087WZ51 A0A087WYR3 TPD52L2 Tumor protein D54 1 MDS(0.126)AGQDINLNS(0.862)PNKGLLS(0.003)DS(0.008)MT(0.001)DVPVDTGVAAR;MDS(0.232)AGQDINLNS(0.679)PNKGLLS(0.057)DS(0.015)MT(0.017)DVPVDTGVAAR 57.563 4.876e-21 7585000.0 4294.9 2639.7 4565.8 6540.2 8242.7 4476.8 2854.7 4880.5 2988.0 4443.6 True False 5660.588860530364 3492.9314028530403 4505.254508759276 5032.457935082729 7098.3433843587 4196.864988294125 3108.7627697133216 4126.330867732945 3145.9395798771006 4288.030916526577 1.320090496249406 0.8145770100189508 1.050658121748958 1.1736057955382369 1.655385309140577 0.9787394424137458 0.7249860904061542 0.9622903724480109 0.7336559929529142 1.0 12.06609959226719 -6.991464765209787 24.998709080132322 0.8520580271510839 1.1857957913986934 0.3716056212954695 0.21423535385707618 229.68234925624967 672709.2868002611 0.07910909032077101 0.06966207900128871 1.0198474980404608e-07 6.991464765209787 0.3337377642476095 (ac)MDSAGQDINLNS(ph)PNKGLLSDSMTDVPVDTGVAAR ddPTM_PC-9_Lapatinib_30min_R1 2 MDSAGQDINLNSPNKGLLSDSMTDVPVDTGVAAR 34 1 A0A087WYR3;O43399;O43399-5;O43399-7;O43399-2;O43399-4;O43399-3;A0A087WZ51 A0A087WYR3 TPD52L2 Tumor protein D54 1 MDS(0.031)AGQDINLNS(0.889)PNKGLLS(0.014)DS(0.056)MT(0.009)DVPVDTGVAAR;MDS(0.29)AGQDINLNS(0.698)PNKGLLS(0.005)DS(0.006)MT(0.001)DVPVDTGVAAR 79.73100000000001 7.7959e-24 11241000.0 12025.099999999999 10803.4 10901.6 8688.0 10942.5 9097.1 11457.7 7811.4 12971.2 5991.2 True False 11853.619868866741 10778.385391058917 10005.312529392937 9326.94450231839 10298.883663782732 8708.03823937586 12050.923643043338 8174.346160917699 11510.246863208575 7026.77093722781 1.6869227664824396 1.5339030526746027 1.4238848282907337 1.3273443215438074 1.4656637815271991 1.23926598962273 1.7150016345626955 1.1633147336011822 1.6380563655814258 1.0 12.778646154177046 -12.63285170978925 0.3004238108290121 1.2382181875359219e-30 1.4827932908323203 0.37519455472414176 0.17753032008494102 80.62230221860099 2.1053733649280195 51.41950123762422 0.17180894252381995 2.3288863220842273e-13 12.63285170978925 1.4827932908323203 (ac)MDT(ph)PLRR ddPTM_PC-9_Lapatinib_30min_R1 1 MDTPLRR 7 1 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 MDT(1)PLRR 40.352 0.016075 4099900.0 19820.0 15051.0 15213.0 19153.0 18637.0 16418.0 15517.0 18797.0 13653.0 16100.0 True False 19537.363165457158 15016.150334230679 13962.24586387822 20561.575512534997 17540.80830175178 15715.840412227286 16320.394334735882 19670.377241822203 12115.255367536276 18882.863548098485 1.0346610362189788 0.7952263329119281 0.739413586732412 1.0889013448707339 0.9289273450010259 0.8322805686857744 0.864296577326025 1.0417052049186164 0.641600535674913 1.0 14.204789942627334 -8.241427849430695 24.95578149998238 0.8208000946029772 0.9075093762370288 0.07148030159456609 0.13422121643412288 2094.847289509813 2612431.0227043666 0.08814425219213971 0.033229188276906685 5.7355114430344045e-09 8.241427849430695 0.08670928163405156 (ac)MDVAES(ph)PERDPHSPEDEEQPQGLSDDDILR ddPTM_PC-9_AZD4547_30min_R2 1 MDVAESPERDPHSPEDEEQPQGLSDDDILR 30 1 E7ERS3;Q86VM9;H3BPD0 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 MDVAES(0.76)PERDPHS(0.239)PEDEEQPQGLSDDDILR 55.818999999999996 0.0011305 8182500.0 4409.9 6576.6 8020.6 7735.4 6286.4 9642.6 6737.6 12840.0 7143.9 6219.9 True False 5812.156468381764 8702.357337577489 7914.241603433058 5952.12304073865 5413.64187116267 9039.646697669086 7337.23334753931 10855.873033847147 7521.5119694390905 6002.143194190219 0.9683468521723452 1.4498749956517105 1.3185692755703757 0.99166628455316 0.9019514690024074 1.5060698162648005 1.222435571787323 1.8086661185216475 1.253137708663723 1.0 12.551262022639245 -6.782991503389675 24.999991468111876 1.4001268412809664 1.147296395400652 0.1641094388457598 0.2507460844835317 410.40065981052066 476052.4112373818 0.08806215885730703 0.07773244861281252 1.6481946367673065e-07 6.782991503389675 -0.25283044588031434 (ac)MDVAES(ph)PERDPHSPEDEEQPQGLSDDDILR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MDVAESPERDPHSPEDEEQPQGLSDDDILR 30 1 E7ERS3;Q86VM9;H3BPD0 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 MDVAES(0.784)PERDPHS(0.216)PEDEEQPQGLSDDDILR 55.691 0.00074239 7858200.0 1238.4 1079.9 830.83 1367.8 1366.2 745.77 1541.0 1246.0 1584.7 0.0 True False 1448.0366604850756 1187.1053351895314 850.6401381403208 1291.1666004674312 1098.5029173487605 706.6605083469473 1395.0253241261464 1213.2938202461273 1607.873239542143 0.0 0.0 (ac)MDVAES(ph)PERDPHSPEDEEQPQGLSDDDILR ddPTM_PC-9_Lapatinib_30min_R1 2 MDVAESPERDPHSPEDEEQPQGLSDDDILR 30 1 E7ERS3;Q86VM9;H3BPD0 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 MDVAES(0.914)PERDPHS(0.086)PEDEEQPQGLSDDDILR;MDVAES(0.979)PERDPHS(0.02)PEDEEQPQGLS(0.001)DDDILR 72.913 4.4173e-15 12013000.0 7811.5 10557.7 12360.8 10122.8 12522.9 14560.2 10969.9 11900.5 12577.2 13611.800000000001 True False 7700.106577546345 10533.254294313158 11344.54273806783 10867.264480670881 11786.327642968681 13937.494187483968 11537.867745867065 12453.440674911173 11160.623292212511 15964.581493416586 0.482324361632761 0.6597889395758242 0.7106069609620552 0.6807108902386375 0.7382797756288871 0.8730259664640416 0.722716580489442 0.7800668423438896 0.6990864932359728 1.0 13.96258711314732 -4.012398012008617 0.0920306905059916 1.1398012665557833 1.9506919482865452e-28 0.6654647096569137 0.0744757955629349 57.82909051295707 0.6811692061608174 1.7776396794592186 8.864947689816027 9.718561516203e-05 4.012398012008617 -1.1398012665557833 (ac)MDVAESPERDPHS(ph)PEDEEQPQGLSDDDILR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MDVAESPERDPHSPEDEEQPQGLSDDDILR 30 1 E7ERS3;Q86VM9;H3BPD0 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 MDVAES(0.267)PERDPHS(0.733)PEDEEQPQGLS(0.001)DDDILR 46.76 0.018961000000000002 10007000.0 1476.9 2036.8 7513.3 5806.8 7989.2 2686.6 5686.0 2426.6 2388.1 5206.1 True False 1726.909999895354 2239.0000432577435 7692.445566348927 5481.463821899608 6423.7736109520665 2545.7099665110013 5147.380916924895 2362.9043211952253 2423.0214446586683 6149.924718535073 0.28080181123041587 0.3640695042184319 1.2508194682716842 0.8913058407656909 1.0445288202620835 0.41394164693407753 0.8369827522296913 0.38421678790209235 0.3939920495865578 1.0 12.58635303513659 -6.780723701263701 24.99928852345393 0.5817875372187795 0.7778207669935945 0.05386632641559652 0.32687273887702517 739.5233774589188 958677.014794682 0.12107393943518238 0.1069354780437659 1.6568237017172254e-07 6.780723701263701 0.19603322977481497 (ac)MEDKVT(ph)SPEKAEEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MEDKVTSPEKAEEAK 15 2 P56211-2;H3BTD3 P56211-2 ARPP19 cAMP-regulated phosphoprotein 19 1 MEDKVT(0.5)S(0.5)PEKAEEAK 56.851000000000006 0.020335 6219100.0 60529.0 45973.0 31221.0 63841.0 66527.0 49228.0 67254.0 88741.0 59353.0 53255.0 True False 70775.36419775608 50536.89561502761 31965.427046301837 60264.19574531462 53491.51191806544 46646.39701905883 60883.21424320563 86411.64277886145 60220.92534015572 62909.70993365197 1.1250308461507716 0.803324251030987 0.5081159503042428 0.9579474425946733 0.8502902330098251 0.7414816737869986 0.9677872351885966 1.3735819616716707 0.9572596250033264 1.0 15.940995089690382 -7.525396485822522 24.94004114683048 1.1333894429247822 0.8244799015055579 0.325597218322661 0.1796496444034477 83.364891655268 825755.7465286793 0.0829654816907193 0.04827115606259298 2.982658380436091e-08 7.525396485822522 -0.3089095414192242 (ac)MEDKVTS(ph)PEKAEEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MEDKVTSPEKAEEAK 15 2 P56211-2;H3BTD3 P56211-2 ARPP19 cAMP-regulated phosphoprotein 19 1 MEDKVT(0.13)S(0.87)PEKAEEAK 66.335 0.019055000000000002 9062000.0 52063.0 53049.0 35793.0 62650.0 55310.0 52918.0 71122.0 80852.0 50736.0 48634.0 True False 60876.23760887799 58315.35413137278 36646.440865708435 59139.9236140405 44472.40254615718 50142.88692318509 64384.80928131063 78729.7206697752 51477.918016918105 57450.959213467846 1.0596209087246569 1.0150457873939605 0.6378734379271713 1.029398367297873 0.7740932989632627 0.8727945992489266 1.1206916327032765 1.3703813086434788 0.8960323504024365 1.0 15.810043360166018 -7.265789848583492 22.18996900312719 1.1276415172952468 0.8919495368136166 0.25145267878869904 0.16427912241369688 96.0024396850294 489658.677765242 0.06558147055925498 0.046096697902612865 5.422632235009998e-08 7.265789848583492 -0.2356919804816302 (ac)MEDLDQSPLVS(ph)SSDSPPRPQPAFK ddPTM_PC-9_AZD4547_30min_R2 3 MEDLDQSPLVSSSDSPPRPQPAFK 24 1 Q9NQC3-5;Q9NQC3;Q9NQC3-2;Q9NQC3-4 Q9NQC3-5 RTN4 Reticulon-4 1 MEDLDQS(0.016)PLVS(0.479)S(0.479)S(0.023)DS(0.002)PPRPQPAFK;MEDLDQS(0.031)PLVS(0.492)S(0.465)S(0.005)DS(0.006)PPRPQPAFK;MEDLDQS(0.005)PLVS(0.437)S(0.437)S(0.119)DS(0.001)PPRPQPAFK 83.666 7.9403e-08 145202000.0 259752.0 237730.0 396198.0 424712.0 382569.0 310890.0 330145.0 389877.0 245435.0 316638.0 True False 342347.7328227624 314571.57343647117 390944.15564882575 326801.210134989 329455.8979716264 291449.9991535836 359527.26542438904 329630.468132183 258408.1930345169 305552.59999710653 1.1204215995085767 1.0295169258564647 1.2794659762428067 1.0695415785631792 1.0782297318849396 0.953845587163531 1.176646068231112 1.0788010579366842 0.8457077211483848 1.0 18.221061231642338 -8.164101242015786 6.55277724521156 0.9244749258612847 1.0992232886847524 0.3871885712806341 0.0885022076719199 0.23119460885113685 12.85266220187813 0.060423363225094395 0.022363968354311488 6.853284451887218e-09 8.164101242015786 0.17474836282346773 (ac)MEDLDQSPLVS(ph)SSDSPPRPQPAFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MEDLDQSPLVSSSDSPPRPQPAFK 24 1 Q9NQC3-5;Q9NQC3;Q9NQC3-2;Q9NQC3-4 Q9NQC3-5 RTN4 Reticulon-4 1 MEDLDQS(0.003)PLVS(0.532)S(0.441)S(0.016)DS(0.008)PPRPQPAFK;MEDLDQS(0.005)PLVS(0.382)S(0.244)S(0.042)DS(0.327)PPRPQPAFK 60.81399999999999 9.7703e-07 268070000.0 140163.0 142315.0 140150.0 136153.0 191452.0 142388.0 142164.0 122189.0 124738.0 118128.0 True False 163889.8275545621 156443.09267293135 143491.7075218351 128524.78882398148 153938.3549496816 134920.92262025183 128697.19674177124 118981.66821994715 126562.05726888894 139543.67129926675 1.1744697987992758 1.1211048929436715 1.0282924778014573 0.9210363152073442 1.1031554030103157 0.966872387432742 0.9222718274751849 0.852648257797216 0.9069709581989046 1.0 17.090357170018116 -3.6508392102158393 0.4034278308062638 0.9161284177394706 1.7686163979606888 0.6175356939615381 0.06193266078730575 9.170757690822903 0.5776008883581003 0.049205322725753356 4.543800248936855 0.00022343993161981954 3.6508392102158393 0.8524879802212182 (ac)MEDLDQSPLVS(ph)SSDSPPRPQPAFK ddPTM_PC-9_Lapatinib_30min_R1 3 MEDLDQSPLVSSSDSPPRPQPAFK 24 1 Q9NQC3-5;Q9NQC3;Q9NQC3-2;Q9NQC3-4 Q9NQC3-5 RTN4 Reticulon-4 1 MEDLDQS(0.047)PLVS(0.451)S(0.451)S(0.017)DS(0.034)PPRPQPAFK;MEDLDQS(0.059)PLVS(0.467)S(0.467)S(0.005)DS(0.003)PPRPQPAFK;MEDLDQS(0.078)PLVS(0.331)S(0.331)S(0.078)DS(0.182)PPRPQPAFK 81.878 4.9834e-06 213158000.0 158284.0 142827.0 117846.0 89606.0 102363.0 107783.0 83242.0 77167.0 136653.0 62041.0 True False 156026.84113426917 142496.29285676504 108157.15677871527 96195.92415685326 96342.20959340116 103173.3723444446 87551.86345376592 80752.4605319835 121261.7001201154 72764.70418556385 2.14426544958351 1.9583161156454694 1.4863958836813784 1.3220135398549182 1.3240239298947767 1.4179040992365315 1.2032188467432232 1.109775150408766 1.6664906629851057 1.0 16.15095119474613 -5.2407379718745 1.7689892228022785 1.2944594066067658 2.182205881099177 0.7629981696915924 0.16859056650447313 0.19992787285275737 1.0672499381475553 0.046400374940020514 0.21728173067701081 5.7446295533028464e-06 5.2407379718745 0.8877464744924111 (ac)MEDLDQSPLVSS(ph)SDSPPRPQPAFK ddPTM_PC-9_AZD4547_30min_R2 1 MEDLDQSPLVSSSDSPPRPQPAFK 24 1 Q9NQC3-5;Q9NQC3;Q9NQC3-2;Q9NQC3-4 Q9NQC3-5 RTN4 Reticulon-4 1 MEDLDQS(0.001)PLVS(0.148)S(0.752)S(0.058)DS(0.041)PPRPQPAFK 74.627 4.6118000000000005e-06 13277000.0 33926.0 28783.0 43894.0 56880.0 50746.0 41914.0 40143.0 46820.0 30037.0 37855.0 True False 44713.762295362656 38086.54186775735 43311.93688016989 43767.194787239794 43700.79383972081 39293.11095411007 43715.649232704585 39585.04481656725 31624.694498249126 36529.707972165226 1.2240383177832543 1.0426182956835677 1.185663376043755 1.1981260518312755 1.196308327266667 1.0756480994605948 1.1967149933422647 1.0836397829057411 0.8657253576279995 1.0 15.156782600022087 -8.072064460705688 4.578735469975598 0.9369392872331002 1.1554387414892682 0.6713679936630914 0.06268023065116325 0.1256713027841573 4.883588727109555 0.04276519384279029 0.015569909304081994 8.471016726760438e-09 8.072064460705688 0.218499454256168 (ac)MEDLDQSPLVSS(ph)SDSPPRPQPAFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MEDLDQSPLVSSSDSPPRPQPAFK 24 1 Q9NQC3-5;Q9NQC3;Q9NQC3-2;Q9NQC3-4 Q9NQC3-5 RTN4 Reticulon-4 1 MEDLDQS(0.004)PLVS(0.173)S(0.734)S(0.012)DS(0.078)PPRPQPAFK 61.861999999999995 2.2161e-05 196770000.0 49620.0 53324.0 49395.0 57180.0 62713.0 48744.0 47458.0 39544.0 49292.0 46415.0 True False 58019.685960327384 58617.65431396109 50572.764131580654 53976.38998006123 50424.83783903735 46187.778831092146 42962.434673834265 38506.011900331345 50012.802248697735 54829.67207906216 1.0581804296889712 1.0690863558227526 0.9223612364242628 0.9844375852226411 0.9196633123453078 0.8423865596805183 0.7835617658242453 0.7022841910272095 0.9121484837002364 1.0 15.742669224854314 -6.0323996361261765 0.919072790936986 0.8249235968948855 1.05928392013935 0.4640969280841818 0.08151021233914643 0.5073431938243103 0.8739813676219224 0.036784781246694404 0.0791858954342515 9.281119486388489e-07 6.0323996361261765 0.23436032324446454 (ac)MEDLDQSPLVSS(ph)SDSPPRPQPAFK ddPTM_PC-9_Lapatinib_30min_R1 3 MEDLDQSPLVSSSDSPPRPQPAFK 24 1 Q9NQC3-5;Q9NQC3;Q9NQC3-2;Q9NQC3-4 Q9NQC3-5 RTN4 Reticulon-4 1 MEDLDQS(0.019)PLVS(0.177)S(0.702)S(0.069)DS(0.033)PPRPQPAFK;MEDLDQSPLVS(0.052)S(0.607)S(0.028)DS(0.313)PPRPQPAFK;MEDLDQS(0.001)PLVS(0.186)S(0.785)S(0.025)DS(0.002)PPRPQPAFK 83.065 2.8723000000000002e-08 206935000.0 196994.0 193208.0 136415.0 105835.0 117501.0 119263.0 97506.0 89168.0 146896.0 64448.0 True False 194184.82943572497 192760.6387466637 125199.4852771278 113618.45895521008 110589.82219585433 114162.39950563177 102554.3835794779 93311.07080378791 130351.02559654362 75587.75092843795 2.568998641321764 2.5501570873455166 1.6563462166728486 1.5031332135120328 1.4630653887367848 1.5103293602916434 1.3567592939307107 1.2344734385883416 1.724499326881049 1.0 16.205864842744777 -5.327764179131445 2.6273315698589226 1.4155941850118439 2.6136651814615295 0.8636218561919944 0.1815615755595623 0.0897465953910852 1.1892922128971337 0.04733400243502458 0.13591091047131215 4.701493292720558e-06 5.327764179131445 1.1980709964496856 (ac)MEDLDQSPLVSSS(ph)DSPPRPQPAFK ddPTM_PC-9_Lapatinib_30min_R1 2 MEDLDQSPLVSSSDSPPRPQPAFK 24 1 Q9NQC3-5;Q9NQC3;Q9NQC3-2;Q9NQC3-4 Q9NQC3-5 RTN4 Reticulon-4 1 MEDLDQSPLVS(0.093)S(0.093)S(0.686)DS(0.129)PPRPQPAFK;MEDLDQS(0.003)PLVS(0.041)S(0.145)S(0.769)DS(0.041)PPRPQPAFK 80.541 1.4353999999999998e-06 68737000.0 109858.0 109832.0 84910.0 57656.0 73209.0 71063.0 58271.0 53203.0 90745.0 40960.0 True False 108291.40477451004 109577.6907520577 77929.02756207857 61896.21457477776 68902.9905544319 68023.80114594399 61287.98725780727 55675.00560710043 80524.34251278701 48039.881424230676 2.25419800307603 2.280973380937368 1.6221736035087757 1.2884339581978679 1.4342872736500585 1.4159860334633068 1.275773075220257 1.1589330355636285 1.6761977782936743 1.0 15.551944969625355 -5.382823775025973 2.7444937441276327 1.3357405219185012 2.2923440757523363 0.8277364059987992 0.17016328571468617 0.09939742381352329 1.4245823987625763 0.04455394431878682 0.1157084229175606 4.1416769879652975e-06 5.382823775025973 0.9566035538338351 (ac)MEDLDQSPLVSSSDS(ph)PPRPQPAFK ddPTM_PC-9_AZD4547_30min_R2 5 MEDLDQSPLVSSSDSPPRPQPAFK 24 1 Q9NQC3-5;Q9NQC3;Q9NQC3-2;Q9NQC3-4 Q9NQC3-5 RTN4 Reticulon-4 1 MEDLDQS(0.002)PLVS(0.046)S(0.111)S(0.111)DS(0.731)PPRPQPAFK;MEDLDQS(0.024)PLVS(0.059)S(0.296)S(0.296)DS(0.325)PPRPQPAFK;MEDLDQS(0.001)PLVS(0.005)S(0.018)S(0.258)DS(0.719)PPRPQPAFK;MEDLDQS(0.021)PLVS(0.125)S(0.125)S(0.125)DS(0.605)PPRPQPAFK;MEDLDQS(0.002)PLVS(0.041)S(0.022)S(0.077)DS(0.858)PPRPQPAFK 73.294 3.5874e-06 254116200.0 154514.0 149898.0 226156.0 243488.0 228355.0 188330.0 179116.0 233386.0 173401.0 197085.0 True False 203646.23790914487 198349.59708484486 223157.02367229477 187355.60345209975 196651.84994422132 176553.69532823295 195056.97700633027 197321.5563767486 182566.62285484248 190185.11413800553 1.0707790608752452 1.0429291376659209 1.1733674566683676 0.98512233358152 1.0340023236599016 0.9283255218393112 1.025616425819686 1.0375236635689826 0.9599417056498187 1.0 17.537044804758764 -5.796039006550412 24.999944207225813 0.997377616239293 1.0904157331891655 0.5155565946036538 0.044270528791440306 144.12634600718752 104137.86393575819 0.012230957501242095 0.01814228725940245 1.5994143693198553e-06 5.796039006550412 0.09303811694987252 (ac)MEDLDQSPLVSSSDS(ph)PPRPQPAFK ddPTM_PC-9_Lapatinib_30min_R1 2 MEDLDQSPLVSSSDSPPRPQPAFK 24 1 Q9NQC3-5;Q9NQC3;Q9NQC3-2;Q9NQC3-4 Q9NQC3-5 RTN4 Reticulon-4 1 MEDLDQS(0.011)PLVS(0.297)S(0.297)S(0.093)DS(0.301)PPRPQPAFK;MEDLDQS(0.012)PLVS(0.051)S(0.051)S(0.082)DS(0.804)PPRPQPAFK 56.081 0.00014129 61399400.0 135144.0 127694.0 102946.0 78758.0 83795.0 81428.0 72861.0 58919.0 102945.0 45885.0 True False 133216.82177762565 127398.33238849606 94482.17726305171 84550.12604898629 78866.34284730865 77945.51425793902 76633.38606838898 61656.5918343844 91350.25004109152 53816.161112080685 2.4754055106268265 2.367287628026251 1.7556469155478704 1.571091737162323 1.4654769351358414 1.4483663020036888 1.4239846262684515 1.1456891491382073 1.6974501367877235 1.0 15.715751861904714 -5.289826655154752 1.0406627922069132 1.3606969573779295 2.7116736654631155 0.8401313067655765 0.1795175770992138 0.32533381277369805 0.4892809108662933 0.05841365571533285 0.4059429970635994 5.130661289870095e-06 5.289826655154752 1.350976708085186 (ac)MEDS(ph)MDMDMSPLRPQNYLFGCELK ddPTM_PC-9_AZD4547_30min_R2 11 MEDSMDMDMSPLRPQNYLFGCELK 24 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 MEDS(0.519)MDMDMS(0.474)PLRPQNY(0.007)LFGCELK;MEDS(0.525)MDMDMS(0.44)PLRPQNY(0.035)LFGCELK;MEDS(0.521)MDMDMS(0.468)PLRPQNY(0.011)LFGCELK;MEDS(0.593)MDMDMS(0.398)PLRPQNY(0.009)LFGCELK;MEDS(0.612)MDMDMS(0.381)PLRPQNY(0.008)LFGCELK;MEDS(0.991)MDMDMS(0.009)PLRPQNYLFGCELK;MEDS(0.974)MDMDMS(0.022)PLRPQNY(0.004)LFGCELK;MEDS(0.5)MDMDMS(0.5)PLRPQNY(0.001)LFGCELK;MEDS(0.58)MDMDMS(0.418)PLRPQNY(0.001)LFGCELK;MEDS(0.97)MDMDMS(0.029)PLRPQNY(0.001)LFGCELK;MEDS(0.518)MDMDMS(0.481)PLRPQNY(0.001)LFGCELK 82.037 4.7166e-06 81735530.0 279694.7 243463.8 344794.60000000003 442661.4 383272.6 364659.4 299519.79999999993 384424.7 287988.2 351042.5 True False 368631.79658883286 322158.71215590107 340222.39831921033 340612.65328045463 330061.8152566459 341857.1900715567 326176.48195326317 325020.69581579225 303210.66831243737 338752.60892402095 1.0882035647185628 0.9510147041499487 1.004338828267206 1.005490863560702 0.9743447181263648 1.0091647446122904 0.962875187852565 0.9594632993326743 0.8950799501604567 1.0 18.369872531950563 -7.457986026953972 2.17546707001447 0.9447451781661516 1.0019959186047647 0.2683320966231566 0.04079843256932966 0.4232032523272363 3.9376736480793664 0.021374135309312196 0.011826365893012808 3.4834852266549105e-08 7.457986026953972 0.05725074043861311 (ac)MEDS(ph)MDMDMSPLRPQNYLFGCELK ddPTM_PC-9_Lapatinib_30min_R1 11 MEDSMDMDMSPLRPQNYLFGCELK 24 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 MEDS(0.523)MDMDMS(0.442)PLRPQNY(0.035)LFGCELK;MEDS(0.565)MDMDMS(0.304)PLRPQNY(0.131)LFGCELK;MEDS(0.476)MDMDMS(0.446)PLRPQNY(0.078)LFGCELK;MEDS(0.756)MDMDMS(0.24)PLRPQNY(0.004)LFGCELK;MEDS(0.753)MDMDMS(0.114)PLRPQNY(0.134)LFGCELK;MEDS(0.809)MDMDMS(0.188)PLRPQNY(0.003)LFGCELK;MEDS(0.909)MDMDMS(0.073)PLRPQNY(0.018)LFGCELK;MEDS(0.829)MDMDMS(0.158)PLRPQNY(0.012)LFGCELK;MEDS(0.513)MDMDMS(0.482)PLRPQNY(0.005)LFGCELK;MEDS(0.471)MDMDMS(0.457)PLRPQNY(0.072)LFGCELK;MEDS(0.514)MDMDMS(0.482)PLRPQNY(0.003)LFGCELK 70.352 4.9133e-05 166782900.0 551902.1 504570.7 611465.0 520642.4 580502.7 538164.7 501033.1 487721.1 605036.9 461386.7 True False 544031.8748475496 503402.39754488156 561192.7080231566 558932.1789081314 546358.67249822 515148.65030418866 526974.1423442136 510382.4028194113 536891.2730009898 541136.7763358671 1.0053500309686687 0.9302683158101142 1.0370625922397878 1.0328852211685928 1.0096498637511042 0.9519749402218628 0.9738279957840765 0.9431670977443094 0.99215447273123 1.0 19.045633766458387 -6.75117600664488 24.998367210931608 0.9687730374362143 1.0025480152013402 0.18974837952812473 0.03143159833247074 345.709992989822 842039.3645093534 0.010831511397550958 0.010718026725667037 1.77347060030851e-07 6.75117600664488 0.033774977765125835 (ac)MEDSMDMDMS(ph)PLRPQNYLFGCELK ddPTM_PC-9_AZD4547_30min_R2 2 MEDSMDMDMSPLRPQNYLFGCELK 24 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 MEDS(0.309)MDMDMS(0.669)PLRPQNY(0.021)LFGCELK;MEDS(0.502)MDMDMS(0.492)PLRPQNY(0.006)LFGCELK 60.765 0.00017403 18964200.0 95848.0 101053.0 113136.0 163935.0 135624.0 125953.0 116327.0 148431.0 117328.0 132823.0 True False 126325.67023775046 133716.40605088003 111635.74271825081 126142.31852050194 116794.94864064743 118077.13899897462 126679.87764474053 125494.39955505953 123529.71855014082 128172.9071981748 0.9855879296116126 1.0432501608482216 0.8709776906725302 0.9841574266975683 0.9112296131355176 0.9212332120735112 0.9883514419227004 0.979102388315388 0.9637740240934467 1.0 16.967731816100525 -7.3052427200307735 24.98220386120833 0.9810655036096294 0.9526782873423735 0.09576087431167546 0.045136978829149986 1328.2999413736131 757559.3969617713 0.019379025423926607 0.013065472338055044 4.9517336921859196e-08 7.3052427200307735 -0.028387216267255933 (ac)MEDSMDMDMS(ph)PLRPQNYLFGCELK ddPTM_PC-9_Lapatinib_30min_R1 4 MEDSMDMDMSPLRPQNYLFGCELK 24 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 MEDS(0.507)MDMDMS(0.486)PLRPQNY(0.006)LFGCELK;MEDS(0.273)MDMDMS(0.726)PLRPQNY(0.001)LFGCELK;MEDS(0.246)MDMDMS(0.751)PLRPQNY(0.003)LFGCELK;MEDS(0.225)MDMDMS(0.774)PLRPQNY(0.002)LFGCELK 60.765 7.9631e-06 16473700.0 75847.5 75756.0 97361.0 83777.0 88826.0 93154.0 75719.0 74905.0 90747.0 67247.4 True False 74765.90074127213 75580.59163643462 89356.35440432817 89938.24005187949 83601.42931863514 89170.02057258022 79639.35932408765 78385.35975414662 80526.1172517261 78871.02348847207 0.9479514457194795 0.9582808526312786 1.1329427520030682 1.1403204380253165 1.05997647324628 1.1305802388327504 1.0097416744658814 0.993842304653287 1.020984814067944 1.0 16.267207743821118 -10.147831534495758 10.479126059353884 0.9999999978751889 1.0473396386704035 0.03414270218482818 0.06770645306934338 0.0 0.0 0.07169983423284491 0.017389764110664507 7.11489451270953e-11 10.147831534495758 0.04733964079521458 (ac)MEDSMDMDMSPLRPQNY(ph)LFGCELK ddPTM_PC-9_Lapatinib_30min_R1 2 MEDSMDMDMSPLRPQNYLFGCELK 24 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 MEDS(0.314)MDMDMS(0.302)PLRPQNY(0.384)LFGCELK;MEDS(0.382)MDMDMS(0.369)PLRPQNY(0.249)LFGCELK 51.503 0.0091551 30503900.0 11967.0 15526.1 18736.7 16298.1 16549.0 16401.6 14183.9 15785.5 16380.0 12915.400000000001 True False 11796.348385520972 15490.150269370733 17196.240851753577 17496.716642867785 15575.62035658583 15700.141801997013 14918.272939644281 16518.951957800946 14535.111910953212 15147.809681311257 0.7787494452135096 1.0226000058927227 1.1352295291225893 1.1550657825107555 1.0282424115614806 1.036462837354446 0.9848468691846473 1.090517527308344 0.959552055165179 1.0 13.886821579824655 -4.769787281703564 4.499316719393323 1.0538598843200058 0.7578059935256277 0.6433155884467119 0.059819422876948004 0.12421855948228645 5.554555563940017 0.015558549927055847 0.11796044552427515 1.6990756593051595e-05 4.769787281703564 -0.29605389079437805 (ac)MEEGGRDKAPVQPQQS(ph)PAAAPGGTDEKPSGK ddPTM_PC-9_AZD4547_30min_R2 3 MEEGGRDKAPVQPQQSPAAAPGGTDEKPSGK 31 3 Q13200;C9JPC0;F8WBS8 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 1 MEEGGRDKAPVQPQQS(0.996)PAAAPGGT(0.004)DEKPS(0.001)GK;MEEGGRDKAPVQPQQS(0.998)PAAAPGGT(0.002)DEKPSGK;MEEGGRDKAPVQPQQS(0.998)PAAAPGGT(0.001)DEKPSGK 49.095 0.002926 115166000.0 190331.0 74130.0 201541.0 506390.0 391152.0 187702.0 134621.0 183630.0 117289.0 247123.0 True False 250852.29886926425 98091.07280884028 198868.43465544976 389649.60914750997 336847.2965749912 175964.9642675087 146602.00820456678 155254.202897613 123488.65708976066 238471.29898838705 1.0519181970048317 0.4113328238029058 0.8339302695924601 1.6339476104689854 1.4125276207406192 0.7378873894425247 0.6147574522655908 0.6510393643017539 0.5178344631559803 1.0 17.863456116773413 -6.9732448496867185 24.48986712105393 0.6681840411200953 1.0530299792347224 0.23652926227751003 0.32593560301917135 284.4917899193694 260403.48602602683 0.12831645590739874 0.1131612824201774 1.0635432370608995e-07 6.9732448496867185 0.3848459381146271 (ac)MEEGGRDKAPVQPQQS(ph)PAAAPGGTDEKPSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MEEGGRDKAPVQPQQSPAAAPGGTDEKPSGK 31 3 Q13200;C9JPC0;F8WBS8 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 1 MEEGGRDKAPVQPQQS(1)PAAAPGGTDEKPSGK 54.096000000000004 1.3523e-09 24571000.0 35886.0 8366.2 22154.0 51657.0 46520.0 69131.0 50163.0 76397.0 63226.0 44713.0 True False 41960.79101919202 9196.741045710398 22682.235379512873 48762.825764253634 37404.73994661422 65505.648661829815 45411.19749133023 74391.65969931266 64150.56063815964 52819.11295208673 0.7944243792442233 0.17411767316223095 0.42943234204043484 0.9232041781634494 0.7081667573733169 1.240188352296853 0.859749339836957 1.4084231169651564 1.214533093282954 1.0 15.688772452535495 -6.28255973000937 1.032045284276396 1.1744762317822166 0.4319359306971721 0.5927861111086213 0.2279000724404367 0.34210520625005864 0.7670033837172955 0.10108287572523866 0.15203051109599308 5.217233449037536e-07 6.28255973000937 -0.7425403010850444 (ac)MEEGGRDKAPVQPQQS(ph)PAAAPGGTDEKPSGK ddPTM_PC-9_Lapatinib_30min_R1 3 MEEGGRDKAPVQPQQSPAAAPGGTDEKPSGK 31 3 Q13200;C9JPC0;F8WBS8 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 1 MEEGGRDKAPVQPQQS(0.994)PAAAPGGT(0.006)DEKPS(0.001)GK;MEEGGRDKAPVQPQQS(1)PAAAPGGTDEKPSGK;MEEGGRDKAPVQPQQS(0.999)PAAAPGGT(0.001)DEKPSGK 57.073 0.00020059 97482000.0 584112.0 116529.0 197517.0 162654.0 116324.0 122675.0 52681.6 57058.4 182017.0 77197.0 True False 575782.4557669781 116259.1842600202 181277.9146976691 174616.1177578379 109482.05102178334 117428.47621939215 55409.19547495146 59709.541565930165 161516.32873601792 90540.39859146332 6.359398287664113 1.2840586751181124 2.0021771222328266 1.928598951123921 1.2092066384177145 1.2969732632750304 0.6119831184416253 0.659479552717144 1.7839144873308148 1.0 16.466274037412667 -4.761235397335931 24.99919652082467 1.3136744821815483 6.359403867305439 0.9160523027736093 0.45870436938702785 1.3779310353039922 168472.58181831375 0.1254185577704357 0.7067660705162261 1.7328644917955977e-05 4.761235397335931 5.045729385123892 (ac)MEEPQS(ph)DPSVEPPLSQETFSDLWK ddPTM_PC-9_AZD4547_30min_R2 1 MEEPQSDPSVEPPLSQETFSDLWK 24 0 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;E7EQX7;E7EMR6;E9PFT5;S4R334;E9PCY9 J3KP33 TP53 Cellular tumor antigen p53 1 MEEPQS(0.497)DPS(0.497)VEPPLS(0.005)QETFSDLWK 66.467 0.00024215 4888800.0 5835.6 4773.0 8384.7 10912.0 9378.1 8578.2 7340.8 10636.0 6430.4 10173.0 True False 7691.199411979549 6315.778908897811 8273.51339953434 8396.406988719422 8076.1126927893 8041.803797932601 7994.1169789860705 8992.450590965595 6770.297816078217 9816.846366420217 0.7834694692063516 0.6433612866247701 0.842787295504079 0.8553059379069443 0.8226789328612374 0.8191840330149835 0.8143263814671658 0.9160223411181646 0.6896611766520957 1.0 13.261043922008353 -14.522878745280336 0.1253642506300423 1.587837660661128 0.7217887049011368 0.36347328114256305 0.07691168481998753 165.95465795168388 1.3246051708648088 25.187749586540612 0.6484466542045468 3.0000000000000132e-15 14.522878745280336 -0.8660489557599912 (ac)MEEPQS(ph)DPSVEPPLSQETFSDLWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MEEPQSDPSVEPPLSQETFSDLWK 24 0 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;E7EQX7;E7EMR6;E9PFT5;S4R334;E9PCY9 J3KP33 TP53 Cellular tumor antigen p53 1 MEEPQS(0.5)DPS(0.5)VEPPLSQETFSDLWK 104.18 2.2545000000000002e-07 4746000.0 2171.2 2855.9 2123.6 2850.3 4069.3 2490.3 1145.0 1211.4 2142.8 1103.3 True False 2538.741276845279 3139.414878014431 2174.2346777978473 2690.606931797281 3271.949876714471 2359.7042840774016 1036.5373109178702 1179.6020335843966 2174.1343962206743 1303.319556282006 1.9479039231848667 2.4087836807806937 1.6682283844495593 2.0644261177763688 2.5104740130259366 1.8105339344473246 0.7953055763812917 0.9050750661253486 1.6681514412496434 1.0 10.347975141200914 -7.0962215763246235 4.836365555169742 1.0919401529044694 2.1130056885089843 0.7140051321852443 0.3073610691464579 0.12390701281231066 4.712247266598441 0.11972511989827114 0.09271328078303914 8.01269152890489e-08 7.0962215763246235 1.0210655356045149 (ac)MEEPQS(ph)DPSVEPPLSQETFSDLWK ddPTM_PC-9_Lapatinib_30min_R1 2 MEEPQSDPSVEPPLSQETFSDLWK 24 0 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;E7EQX7;E7EMR6;E9PFT5;S4R334;E9PCY9 J3KP33 TP53 Cellular tumor antigen p53 1 MEEPQS(0.714)DPS(0.286)VEPPLSQETFSDLWK;MEEPQS(0.495)DPS(0.495)VEPPLS(0.01)QETFSDLWK 106.42 9.750400000000001e-08 2494060.0 14522.5 12914.8 15392.3 11631.2 14068.5 13867.7 12237.5 12626.400000000001 14612.2 12485.8 True False 14315.406486899667 12884.89657408295 14126.804509996231 12486.597248545768 13241.018489735205 13274.61079818762 12871.097871452635 13213.068638939398 12966.4201627125 14643.953893717277 0.9775642965552789 0.8798782533459752 0.9646851261978557 0.8526793609957292 0.9041969529428814 0.9064908899967823 0.8789359734992575 0.9022883256009312 0.8854453009631168 1.0 13.838017516006666 -4.749460401846412 24.921253474653078 0.9041586627596189 0.9775644693141479 0.19603352134562846 0.04133277924320252 782.9387120501345 1628733.2349982583 0.009390031687641215 0.15256164232832709 1.7804902432027263e-05 4.749460401846412 0.073405806554529 (ac)MEEPQSDPSVEPPLS(ph)QETFSDLWK ddPTM_PC-9_AZD4547_30min_R2 1 MEEPQSDPSVEPPLSQETFSDLWK 24 0 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;E7EQX7;E7EMR6;E9PFT5;S4R334;E9PCY9 J3KP33 TP53 Cellular tumor antigen p53 1 MEEPQS(0.142)DPS(0.142)VEPPLS(0.713)QET(0.002)FS(0.001)DLWK 70.718 2.4339000000000002e-05 6362500.0 5949.8 4957.9 7145.3 8042.1 8366.4 7321.9 5924.4 6463.7 5973.3 7777.4 True False 7841.71263647199 6560.444217981242 7050.548653343917 6188.118094206419 7204.869774576129 6864.0604355322475 6451.660122916453 5464.8836860496685 6289.036443266358 7505.115593256316 1.044849015186138 0.874129670151396 0.9394323865816473 0.8245200246837933 0.9599945110838838 0.914584239275397 0.8596350106470791 0.7281544991738851 0.8379666329080048 1.0 12.87365857696553 -7.337059548115016 4.089482472086791 0.8307464152076393 0.9216134255578893 0.12256309680703514 0.08256663518765571 0.37197165345831595 11.891978083561325 0.03470158283157376 0.022951456737540465 4.601934700107835e-08 7.337059548115016 0.09086701035025002 (ac)MEEPQSDPSVEPPLS(ph)QETFSDLWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MEEPQSDPSVEPPLSQETFSDLWK 24 0 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;E7EQX7;E7EMR6;E9PFT5;S4R334;E9PCY9 J3KP33 TP53 Cellular tumor antigen p53 1 MEEPQSDPSVEPPLS(0.965)QET(0.033)FS(0.002)DLWK;MEEPQSDPSVEPPLS(0.979)QET(0.02)FS(0.001)DLWK 92.632 1.9919e-07 6196800.0 39164.0 40281.0 48829.0 48248.0 57752.0 51114.0 53713.0 48337.0 49504.0 37753.0 True False 45793.69167574088 44279.83147214512 49993.2685450137 45544.82098212653 46435.91017620085 48433.491858945614 48624.915791555904 47068.204967284924 50227.90234763314 44597.32004741642 1.0268260879140825 0.99288099430787 1.120992662605292 1.021245692200848 1.0412264711608146 1.0860179895888482 1.0903102639319424 1.0554043363422159 1.1262538263337398 1.0 15.444669397532053 -6.751324171320988 24.390978633432578 1.0762296144473806 1.0413686045547301 0.11081763583821891 0.04283529065480116 317.4808877814035 765545.304551775 0.013762990603544273 0.013602835994320267 1.772865663128049e-07 6.751324171320988 -0.03486100989265051 (ac)MEEPQSDPSVEPPLS(ph)QETFSDLWK ddPTM_PC-9_Lapatinib_30min_R1 2 MEEPQSDPSVEPPLSQETFSDLWK 24 0 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;E7EQX7;E7EMR6;E9PFT5;S4R334;E9PCY9 J3KP33 TP53 Cellular tumor antigen p53 1 MEEPQS(0.072)DPS(0.072)VEPPLS(0.855)QET(0.001)FSDLWK;MEEPQSDPS(0.001)VEPPLS(0.986)QET(0.012)FS(0.001)DLWK 75.17399999999999 1.3191999999999998e-06 5975900.0 23568.0 20907.3 24821.4 21199.6 21962.0 23670.5 20164.2 19563.9 23884.6 17967.3 True False 23231.915998158114 20858.890431390693 22780.680305374794 22758.689303792453 20670.2383389533 22658.167893630525 21208.20361181166 20472.910215528307 21194.464832011807 21072.92386507764 1.102453373196037 0.9898432018709257 1.0810403174818695 1.079996750783525 0.9808908564989561 1.0752265816885513 1.0064196002225494 0.9715267965000489 1.005767636599095 1.0 14.36310288131709 -7.443177044224333 5.824106155502081 0.9909345145891038 1.0479955659802802 0.3420521082553095 0.037943391897600064 0.26089711366138746 14.772479708843479 0.015675974789070294 0.010357778879960061 3.604316797088728e-08 7.443177044224333 0.057061051391176454 (ac)MEGAAAPVAGDRPDLGLGAPGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 MEGAAAPVAGDRPDLGLGAPGSPR 24 1 O60285-2;O60285 O60285-2 NUAK1 NUAK family SNF1-like kinase 1 1 MEGAAAPVAGDRPDLGLGAPGS(1)PR 59.618 0.00023782 0.0 683.51 591.02 3284.4 610.78 583.52 777.17 1013.6 492.93 2407.7 1239.4 True False 673.7630220596172 589.6515295021607 3014.3693101506346 655.6987987023513 549.1985008444599 743.9322507717557 1066.0792484171106 515.8333273294368 2136.5194717949985 1453.6286386033084 0.46350422946192754 0.4056411065681233 2.0736859677220822 0.4510772430380617 0.37781210844342394 0.511776000427832 0.7333917481437575 0.35485908410903727 1.4697835575445408 1.0 10.50544303282224 -10.50667127396397 9.304720167466746 0.9999986571226254 0.7480245999266446 0.01702422525632541 0.5396604504927534 7.393213400639514e-10 0.0 0.5212886573790514 0.12643107034177908 3.1140725480284845e-11 10.50667127396397 -0.25197405719598076 (ac)MEGGLADGEPDRTS(ph)LLGDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MEGGLADGEPDRTSLLGDSK 20 1 F8VQX7;Q9BZF1;F8W060;F8VZB8 F8VQX7 OSBPL8 Oxysterol-binding protein;Oxysterol-binding protein-related protein 8 1 MEGGLADGEPDRT(0.079)S(0.892)LLGDS(0.029)K 50.493 0.022783 0.0 10408.0 17004.0 8027.6 6613.7 11148.0 6567.3 8461.4 4273.2 5419.5 7436.7 True False 12169.868832629738 18692.044744478913 8219.008428842539 6243.155830904704 8963.6294265876 6222.899226929092 7659.874936768963 4161.033027829654 5498.7499348133015 8784.914841115193 1.3853143772859664 2.1277434195487395 0.9355820264046162 0.7106677689902539 1.020343348649891 0.7083619294525947 0.871935024448864 0.47365661512792034 0.6259309320880415 1.0 13.100812585819327 -5.384369484671776 5.395481500501562 0.7676042902121304 1.748071910943669 0.7410159322503588 0.22900683424847418 0.09705832747782828 3.827523260767006 0.058185603078663745 0.12423573040239257 4.126962430507573e-06 5.384369484671776 0.9804676207315387 (ac)MEGIS(ph)NFKTPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MEGISNFKTPSK 12 1 Q96KB5;Q96KB5-2;E5RIE1 Q96KB5 PBK Lymphokine-activated killer T-cell-originated protein kinase 1 MEGIS(0.954)NFKT(0.04)PS(0.006)K 66.962 0.019758 22894000.0 258880.0 226980.0 222970.0 227260.0 274170.0 204490.0 233230.0 185510.0 183190.0 157010.0 True False 302703.27088693157 249513.0743414393 228286.45041843381 214527.35898686084 220448.35664581246 193766.18441592867 211136.76596102628 180640.55906409267 185868.8071885691 185474.6701095234 1.632046417487543 1.3452676540365378 1.2308227871958468 1.1566396579122191 1.1885631418869056 1.0447042946700436 1.1383590321867094 0.9739365432348461 1.0021250183586414 1.0 17.500862648870033 -1.5228787452803376 0.3996167780605918 1.0131000976941709 10.780458383363019 0.9327595858854302 0.0492435691225698 17.039483010998364 0.2261613769619538 0.03588074987603545 130.99115484096265 0.029999999999999995 1.5228787452803376 9.767358285668848 (ac)MEGISNFKT(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MEGISNFKTPSK 12 1 Q96KB5;Q96KB5-2;E5RIE1 Q96KB5 PBK Lymphokine-activated killer T-cell-originated protein kinase 1 MEGIS(0.012)NFKT(0.858)PS(0.129)K 49.31 0.021709 7363400.0 94681.0 93142.0 74246.0 80271.0 98747.0 74555.0 87706.0 71997.0 64506.0 60343.0 True False 110708.62326500897 102388.52220596666 76016.30621952299 75773.67611209315 79398.23421127051 70645.20455342346 79397.85274354817 70107.1550371272 65449.2782166375 71282.70822507475 1.5530922719076148 1.436372505414293 1.0664059785649829 1.0630022062691304 1.1138498548704272 0.991056685590026 1.1138445033941458 0.9835085784867243 0.9181648655937955 1.0 16.12126452938154 -5.202594044347497 2.685359959946124 1.030872501638764 1.5464512382269282 0.9141085918319661 0.057437437733846304 0.07740821808350312 1.0613177880659916 0.016166509556270605 0.057050198904034816 6.271998642124806e-06 5.202594044347497 0.5155787365881641 (ac)MEGISNFKT(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 1 MEGISNFKTPSK 12 1 Q96KB5;Q96KB5-2;E5RIE1 Q96KB5 PBK Lymphokine-activated killer T-cell-originated protein kinase 1 MEGIS(0.005)NFKT(0.861)PS(0.134)K 52.576 0.023048 5333000.0 61320.0 68803.0 85358.0 81272.0 87083.0 68219.0 62972.0 50067.0 65313.0 53249.0 True False 60445.56555528919 68643.69088074384 78340.19473140835 87249.01399544433 81960.94915176522 65301.432396256096 66232.38203563764 52393.29559856957 57956.76216361948 62453.018700167515 0.9678565874531068 1.0991252674317842 1.2543860386879622 1.397034375781267 1.3123616897568056 1.0456089033864577 1.0605153027688634 0.8389233489273921 0.928005777300626 1.0 15.930483686506905 -7.221558060308348 2.008899463630749 0.923647708979688 1.2088208185953517 0.47691656138830774 0.12230327735388256 0.3080416807543204 2.4309113309370485 0.06697631524997694 0.04404335087715898 6.00401736553933e-08 7.221558060308348 0.2851731096156638 (ac)MEPAPARS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 MEPAPARSPR 10 1 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BT57;P29590-14;P29590-10;P29590-2 P29590;P29590-2 PML Protein PML 1 MEPAPARS(1)PR 67.08 0.025021 3378100.0 4210.7 10745.0 13985.0 17983.0 14243.0 12901.0 9544.0 14956.0 13730.0 11138.0 True False 5549.615011999162 14218.111120072701 13799.549762363325 13837.297184580395 12265.605302075886 12094.29843057151 10393.397510822124 12644.893854689857 14455.739769649463 10748.062010143349 0.5163363410782131 1.3228534694584508 1.2839105086424114 1.287422529896238 1.1411922717323715 1.1252538754575168 0.9670020047347592 1.1764812896275065 1.344962445881596 1.0 13.391788929558777 -4.754189524822184 24.999470886904515 1.1852655602470938 0.5163351717144977 0.7245142237774509 0.1233628226323137 141.91123121357407 489306.94512096356 0.032197911993893505 0.32173659286651557 1.7612072930505337e-05 4.754189524822184 -0.6689303885325961 (ac)MERS(ph)PPQSPGPGK ddPTM_PC-9_AZD4547_30min_R2 4 MERSPPQSPGPGK 13 1 Q86VQ6 Q86VQ6 TXNRD3 Thioredoxin reductase 3 1 MERS(0.999)PPQS(0.001)PGPGK;MERS(1)PPQSPGPGK;MERS(0.997)PPQS(0.003)PGPGK;MERS(0.976)PPQS(0.024)PGPGK 77.89399999999999 0.00092583 17104500.0 71177.5 63219.5 88928.3 135455.2 120729.1 93099.1 77649.1 96510.1 79031.4 97806.1 True False 93810.46441602838 83653.96705029656 87749.05263728097 104228.09640197827 103967.94840095859 87277.59855961702 84559.71947376132 81596.68162647127 83208.8384581991 94381.93820886007 0.9939450936940174 0.8863344898170736 0.9297229353681948 1.1043224835172318 1.10156615104561 0.9247277627047489 0.8959311609668057 0.8645370414613016 0.881618242190198 1.0 16.52622317822911 -6.980083264894217 24.924918562620068 0.9008182119287967 0.9997173880120803 0.28198956293047395 0.07116845751000524 319.2348897949919 399507.0437260546 0.027670811896791367 0.024400529378925957 1.0469278070932919e-07 6.980083264894217 0.09889917608328358 (ac)MERS(ph)PPQSPGPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 MERSPPQSPGPGK 13 1 Q86VQ6 Q86VQ6 TXNRD3 Thioredoxin reductase 3 1 MERS(0.99)PPQS(0.01)PGPGK;MERS(0.999)PPQS(0.001)PGPGK;MERS(0.997)PPQS(0.003)PGPGK;MERS(0.994)PPQS(0.006)PGPGK 79.65899999999999 0.0057076 48727000.0 68434.0 72343.9 79988.6 86998.0 100359.5 104410.2 76983.0 70797.8 71925.1 72297.09999999999 True False 80018.52456688923 79525.72428782092 81895.83158245496 82123.78411132135 80694.77641169888 98934.74530834766 69690.61293134517 68939.43276646982 72976.86851857946 85403.99192647141 0.936941268925476 0.9311710435770802 0.9589227591722317 0.9615918677668586 0.9448595386638726 1.1584323294106154 0.8160111882281255 0.8072155787029632 0.854490134154489 1.0 16.38201588496812 (ac)MERS(ph)PPQSPGPGK ddPTM_PC-9_Lapatinib_30min_R1 3 MERSPPQSPGPGK 13 1 Q86VQ6 Q86VQ6 TXNRD3 Thioredoxin reductase 3 1 MERS(0.997)PPQS(0.003)PGPGK;MERS(0.996)PPQS(0.004)PGPGK;MERS(0.999)PPQS(0.001)PGPGK 74.649 0.00011875 31777800.0 95444.0 72816.0 97467.0 73612.0 73628.0 83103.0 59686.0 64860.0 79346.0 51167.7 True False 94082.951057714 72647.39902580177 89453.63949350039 79025.67204243348 69297.34579821755 79548.87841255477 62776.249034159046 67873.63238307119 70409.21792957839 60011.96876832544 1.5677364530552007 1.2105485041868076 1.4905966481258717 1.316831853117666 1.1547254192865768 1.3255502201511007 1.0460621493106657 1.1310015947834589 1.1732529256187418 1.0 15.872962639615663 -1.5228787452806534 0.15003466885292233 0.9448263473387094 2.9366535885507825 0.6312990148819388 0.10571204217686295 44.54632979219496 0.4397119566108416 0.3643887355627336 19.304302988389548 0.029999999999978186 1.5228787452806534 1.9918272412120732 (ac)MES(ph)PTKEIEEFESNSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MESPTKEIEEFESNSLK 17 1 Q14123-2;Q14123;F8W905 Q14123-2 PDE1C Calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase 1C 1 MES(0.5)PT(0.5)KEIEEFESNSLK;MES(0.5)PT(0.5)KEIEEFESNSLK 89.301 0.00013475 0.0 16470.300000000003 17715.300000000003 14921.8 19196.4 19174.7 15829.7 20777.8 19070.300000000003 17294.0 12612.4 True False 19258.39648674688 19473.95790766099 15277.592303241629 18120.8879435685 15417.55518173567 14999.562665405789 18809.576365754856 18569.72483165306 17546.89203296639 14898.928280296535 1.2926028050095142 1.3070710551318527 1.0254155208899063 1.2162544582171677 1.0348096783662626 1.0067544714100234 1.2624784824711222 1.24637990614473 1.1777284716627383 1.0 13.862920937061721 -5.237485645304649 24.309554286582635 1.1312907134495256 1.2998370161052037 0.3502133909502939 0.09654035593436354 671.5859961340641 681558.0572950831 0.025486753100531008 0.06734021092230712 5.787811184317536e-06 5.237485645304649 0.16854630265567816 (ac)MESPT(ph)KEIEEFESNSLK ddPTM_PC-9_AZD4547_30min_R2 1 MESPTKEIEEFESNSLK 17 1 Q14123-2;Q14123;F8W905 Q14123-2 PDE1C Calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase 1C 1 MES(0.449)PT(0.551)KEIEEFESNSLK 80.52199999999999 0.0061786 0.0 9796.9 10041.0 7910.0 11069.0 9728.4 10558.0 10917.0 10086.0 9452.6 11865.0 True False 12912.110411820975 13286.556887543049 7805.108231697809 8517.213064345235 8377.779584407439 9897.806590959919 11888.591850968694 8527.44045322292 9952.245138134629 11449.609961424936 1.1277336481612363 1.160437511173481 0.6816920626985656 0.7438867431327978 0.7317087317937598 0.8644667044822293 1.0383403356990097 0.7447799952970324 0.8692213247145446 1.0 13.483010832343076 -5.246473423882651 24.935542626789413 0.826623936900081 1.1440856482854285 0.5561046495074234 0.1105542917083126 568.9215267723852 947905.308958728 0.028978110380642515 0.07600730498830166 5.6692626281799585e-06 5.246473423882651 0.3174617113853475 (ac)MESRDPAQPMS(ph)PGEATQSGARPADR ddPTM_PC-9_AZD4547_30min_R2 1 MESRDPAQPMSPGEATQSGARPADR 25 2 Q9BQG0;Q9BQG0-2 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 MES(0.107)RDPAQPMS(0.892)PGEAT(0.002)QSGARPADR 60.398 0.035432 0.0 1337.5 721.46 2137.3 2950.9 1921.7 2236.9 1241.4 2613.5 944.42 821.07 True False 1762.7971782717548 954.6578360807496 2108.958005512988 2270.6155959505268 1654.9051259565574 2097.026289384188 1351.8821950895415 2209.6436272554147 994.3401131283564 792.3245892142573 2.224842195065419 1.2048822529002627 2.6617348927721993 2.8657643936082815 2.0886706641248067 2.6466757663848277 1.7062226939469258 2.788811122783281 1.2549656121545292 1.0 9.629947765681306 -8.400978849442321 5.509146810291211 1.014311668374494 2.2554552329441315 0.46741892417196884 0.49173829876623876 0.19398923126174988 7.3570649890197535 0.4736827358173956 0.12309465428277847 3.972108935497684e-09 8.400978849442321 1.2411435645696376 (ac)MESRDPAQPMS(ph)PGEATQSGARPADR ddPTM_PC-9_Lapatinib_30min_R1 1 MESRDPAQPMSPGEATQSGARPADR 25 2 Q9BQG0;Q9BQG0-2 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 MES(0.03)RDPAQPMS(0.869)PGEAT(0.089)QS(0.012)GARPADR 46.353 0.031276 0.0 915.24 1098.6 2724.1 2132.2 2751.8 986.7 1088.0 1078.3 3006.6 933.46 True False 902.1885097655397 1096.056259197783 2500.1350133300907 2289.00910081069 2589.9445342469585 944.5011411100411 1144.331316375114 1128.4017545276852 2667.965047098409 1094.8073172427337 0.8240614540627081 1.001140787000031 2.2836301639147494 2.090787177578925 2.3656624261241874 0.8627099273402393 1.045235356352117 1.0306852509622961 2.436926576100774 1.0 10.096461266891302 -6.78130742152197 24.999511166941826 1.2626621889173848 1.7261894903444774 0.10912530270568122 0.6245852315562709 604.8477305410321 761061.1738719202 0.2346375704332775 0.20719854970580834 1.654598317898088e-07 6.78130742152197 0.46352730142709264 (ac)MET(ph)MASPGKDNYR ddPTM_PC-9_AZD4547_30min_R2 5 METMASPGKDNYR 13 1 S4R3E5;O60684 S4R3E5 KPNA6 Importin subunit alpha-7 1 MET(0.63)MAS(0.37)PGKDNYR;MET(0.949)MAS(0.051)PGKDNYR;MET(0.999)MAS(0.001)PGKDNYR;MET(1)MASPGKDNYR;MET(1)MASPGKDNYR 148.91 4.4446e-05 181701000.0 228446.0 192146.0 249738.0 317320.0 322394.0 262497.0 250208.0 275262.0 243133.0 281558.0 True False 301087.0760280147 254253.4368801759 246426.31094408932 244166.77654512896 277635.1580255184 246083.02109369304 272476.027282877 232726.58279149776 255984.51401414312 271700.7401195857 1.108156996169738 0.93578485199661 0.9069769586775062 0.898660697198182 1.0218417436158649 0.905713473527465 1.002853459887338 0.8565548356219642 0.94215611595859 1.0 18.05165896993929 -4.761063110844587 24.99999812601844 0.9376321015116877 1.1081571793019522 0.49675394418632746 0.05030860152469879 7.223874210972896 479343.0576972889 0.011909590352111239 0.0680838921309118 1.733552062974617e-05 4.761063110844587 0.1705250777902645 (ac)MET(ph)MASPGKDNYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 METMASPGKDNYR 13 1 S4R3E5;O60684 S4R3E5 KPNA6 Importin subunit alpha-7 1 MET(0.972)MAS(0.028)PGKDNYR;MET(0.705)MAS(0.295)PGKDNYR 80.24 0.0028969 9023000.0 33237.0 33469.0 34161.0 42723.0 44874.0 40148.0 40388.0 39481.0 32625.0 30491.0 True False 38863.367639326905 36791.581131084735 34975.52779631395 40329.36881983485 36081.26183070434 38042.568203485294 36562.156256201655 38444.66558357732 33102.07890456391 36018.776933376794 1.0789752164881026 1.0214555924299535 0.9710359644084384 1.1196762426006655 1.0017347867597814 1.0561871180093612 1.0150860014994385 1.067350666978161 0.9190228464945426 1.0 15.1364615729505 -8.255970087479616 24.999056528494037 0.9595114215340718 1.0393226829323308 0.35602224648726455 0.04400025386090652 441.6055694413794 2018516.9518719632 0.029838996040299492 0.010535209654825283 5.546639147426097e-09 8.255970087479616 0.079811261398259 (ac)MET(ph)MASPGKDNYR ddPTM_PC-9_Lapatinib_30min_R1 9 METMASPGKDNYR 13 1 S4R3E5;O60684 S4R3E5 KPNA6 Importin subunit alpha-7 1 MET(0.981)MAS(0.019)PGKDNYR;MET(1)MASPGKDNYR;MET(0.998)MAS(0.002)PGKDNYR;MET(0.986)MAS(0.014)PGKDNYR;MET(0.999)MAS(0.001)PGKDNYR;MET(0.998)MAS(0.002)PGKDNYR;MET(0.549)MAS(0.451)PGKDNYR;MET(0.995)MAS(0.005)PGKDNYR;MET(1)MASPGKDNYR 149.33 1.3895999999999999e-05 200044700.0 537046.0 510290.0 523974.0 525776.0 508731.0 472008.0 456071.0 424501.0 482155.0 369428.0 True False 529387.6255578267 509108.45485712436 480894.8803181316 564443.3209773201 478808.44278362906 451821.3181443893 479684.12480745843 444224.8661770902 427849.6265827624 433283.137568133 1.2218052807895887 1.1750017730082283 1.109885981294418 1.3027124114391881 1.1050705676454746 1.0427853728171943 1.1070916064256688 1.025253068167779 0.9874596758695319 1.0 18.724950565604153 -6.5100321724833305 5.474021862344922 1.0414748667355425 1.1955122506890692 0.6843486120882429 0.054081622434353264 0.11057386782950003 10.908498078567623 0.017680710570767703 0.018939803847447742 3.0900665122764705e-07 6.5100321724833305 0.15403738395352673 (ac)MET(ph)PGASASSLLLPAASRPPR ddPTM_PC-9_Lapatinib_30min_R1 1 METPGASASSLLLPAASRPPR 21 1 Q96DF8;F8WEF8 Q96DF8 DGCR14 Protein DGCR14 1 MET(0.566)PGAS(0.433)AS(0.001)SLLLPAASRPPR 72.681 0.00033396 3997800.0 4124.2 1581.2 3729.3 3972.8 1739.7 1862.7 1777.0 4909.7 4597.0 1034.2 True False 4065.388151714347 1577.538828548638 3422.6913495142994 4264.972964872296 1637.3742663817977 1783.036663165779 1869.0043650722225 5137.822585741049 4079.237451443954 1212.9600920151224 3.3516256457872498 1.3005694407701671 2.8217674860415998 3.5161692399844617 1.3498995368112936 1.469987903891853 1.5408622075662823 4.235772157355523 3.3630434161003677 1.0 10.24431636933402 -7.740262989081369 24.998831031850028 3.0995574299022084 2.1735016123466386 0.06287775196753276 1.0823599913259168 475.3004585135082 561095.4765802476 0.5063476538567354 0.2919721366174081 1.8185992637042864e-08 7.740262989081369 -0.9260558175555698 (ac)MET(ph)PSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 METPSQR 7 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 MET(0.973)PS(0.027)QR;MET(0.962)PS(0.038)QR 68.22399999999999 0.017887 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)MET(ph)PSQR ddPTM_PC-9_Lapatinib_30min_R1 1 METPSQR 7 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 MET(0.956)PS(0.044)QR 51.066 0.038284 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)MET(ph)PSQRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 METPSQRR 8 1 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 MET(0.948)PS(0.052)QRR 65.22399999999999 0.00099255 8138800.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)MET(ph)PSQRR ddPTM_PC-9_Lapatinib_30min_R1 1 METPSQRR 8 1 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 MET(0.948)PS(0.052)QRR 65.22399999999999 0.0010629 4587500.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)METMAS(ph)PGKDNYR ddPTM_PC-9_AZD4547_30min_R2 4 METMASPGKDNYR 13 1 S4R3E5;O60684 S4R3E5 KPNA6 Importin subunit alpha-7 1 MET(0.007)MAS(0.993)PGKDNYR;MET(0.085)MAS(0.915)PGKDNYR;MET(0.041)MAS(0.959)PGKDNYR;MET(0.006)MAS(0.994)PGKDNYR 61.532 0.00052453 7187800.0 31291.399999999998 27558.6 38824.5 58383.0 50648.3 42322.7 42828.8 44056.2 39492.899999999994 43609.1 True False 41241.41429844693 36466.378512204305 38309.661762522344 44923.7013583583 43616.65779829603 39676.254878501575 46640.48022962055 37248.32660076139 41580.414067646685 42082.35868257698 0.9800167003358055 0.866547875494968 0.910349680052116 1.0675186174143252 1.0364594372499913 0.9428239319420186 1.108314307698982 0.8851292505185318 0.9880723269644552 1.0 15.360927948350085 -5.731334253998999 24.8093952955207 1.0024033592706445 0.9137289549756887 0.2702748197439656 0.06384556925213081 244.68249127657967 201638.89207955444 0.017081436006461344 0.029581250045251684 1.856375149198827e-06 5.731334253998999 -0.08867440429495577 (ac)METMAS(ph)PGKDNYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 METMASPGKDNYR 13 1 S4R3E5;O60684 S4R3E5 KPNA6 Importin subunit alpha-7 1 MET(0.133)MAS(0.867)PGKDNYR;MET(0.037)MAS(0.963)PGKDNYR;MET(0.342)MAS(0.657)PGKDNYR 85.67200000000001 5.2311e-05 144490400.0 48379.4 44185.6 40970.1 54394.1 57639.3 52655.8 53381.6 58523.4 48725.3 39652.3 True False 56569.076883294285 48572.05435554267 41946.98256396951 51346.57492505156 46345.29293217715 49894.43715276184 48324.90839868415 56987.22276066787 49437.8153332888 46840.948102565904 1.2076842842597262 1.0369571138736609 0.8955195029810188 1.0961899151276753 0.9894183360827062 1.0651884552701587 1.0316808338906565 1.216611214527192 1.0554401081941518 1.0 15.515482657118445 (ac)METMAS(ph)PGKDNYR ddPTM_PC-9_Lapatinib_30min_R1 4 METMASPGKDNYR 13 1 S4R3E5;O60684 S4R3E5 KPNA6 Importin subunit alpha-7 1 MET(0.093)MAS(0.907)PGKDNYR;MET(0.02)MAS(0.98)PGKDNYR;MET(0.013)MAS(0.987)PGKDNYR;MET(0.001)MAS(0.999)PGKDNYR 93.766 2.4204e-05 102648000.0 181869.0 147418.0 166573.0 164613.0 153171.0 148466.0 136877.0 138407.0 149292.0 120346.0 True False 179275.51470931002 147076.6626783348 152878.0109303744 176719.18915287 144161.78292577245 142116.45527114967 143963.82131569533 144837.89449959507 132477.1628455449 141147.64574903483 1.2701275586846685 1.0420057798189704 1.0831070551626243 1.2520165548285698 1.0213544984101035 1.0068638022049436 1.0199519839790154 1.026144600081546 0.9385715372192156 1.0 17.10684554020977 -6.414996726187425 7.734116545694665 1.002692492821128 1.1473919313851284 0.5674640176992152 0.06800870943703974 0.23165586797397478 14.862824982822351 0.020969136033809718 0.023759079387279676 3.8459468119837143e-07 6.414996726187425 0.14469943856400036 (ac)METPS(ph)QRR ddPTM_PC-9_AZD4547_30min_R2 2 METPSQRR 8 1 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 METPS(1)QRR;MET(0.051)PS(0.949)QRR 91.867 0.0024973 8200700.0 0.0 0.0 520.58 792.48 0.0 0.0 0.0 0.0 603.77 613.89 True False 0.0 0.0 513.6767690590705 609.7859796939481 0.0 0.0 0.0 0.0 635.6840495791149 592.3978979535738 0.0 0.0 0.8671144358100462 1.029352031464732 0.0 0.0 0.0 0.0 1.0730693876110504 1.0 9.21042271119599 -8.271394264104591 24.7260895713147 1.036534914258819 0.2528621961215745 0.4275543404988533 0.36966845946749527 725.7824515623607 1802685.5168700346 0.3805866017717989 0.10310980602705386 5.3531046775010806e-09 8.271394264104591 -0.7836727181372445 (ac)METPS(ph)QRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 METPSQRR 8 1 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 MET(0.196)PS(0.804)QRR;MET(0.252)PS(0.748)QRR 71.34899999999999 0.001695 22612000.0 0.0 0.0 0.0 0.0 0.0 0.0 756.89 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 685.1918997909402 0.0 0.0 0.0 0.0 (ac)METPS(ph)QRR ddPTM_PC-9_Lapatinib_30min_R1 4 METPSQRR 8 1 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 MET(0.007)PS(0.993)QRR;METPS(1)QRR;METPS(1)QRR;METPS(1)QRR 91.867 0.0029166 11348700.0 18766.09 25685.89 32888.119999999995 30943.0 34807.84 31993.0 27957.260000000002 37086.7 34623.0 30702.98 True False 18498.48211532057 25626.415899841384 30184.18572541447 33218.65144282206 32760.511286046436 30624.733969325574 29404.75012687621 38809.88347365475 30723.39314364672 36009.94918385075 0.5137047547852834 0.7116482105821457 0.8382179483594234 0.922485374062108 0.9097627746927902 0.8504520184954811 0.8165729414598354 1.07775446378746 0.8531917939341366 1.0 15.136107943191549 -4.51135389491477 0.9481978677919051 0.9205460995673839 0.09209266486274481 0.7611276694430409 0.07194632509961778 1.5163589958189496 0.7681449609002902 0.024020990822311388 1.4569469552602965 3.0806765665247095e-05 4.51135389491477 -0.8284534347046391 (ac)MEVAEPS(ph)SPTEEEEEEEEHSAEPRPR ddPTM_PC-9_AZD4547_30min_R2 2 MEVAEPSSPTEEEEEEEEHSAEPRPR 26 1 M0R3H9;M0QXG9;M0R3F4;M0R2A4;M0R2K3;M0R193;M0R0I0;J3KQS6;Q9NWV8-3;Q9NWV8 M0R3H9 BABAM1 BRISC and BRCA1-A complex member 1 1 MEVAEPS(0.433)S(0.433)PT(0.135)EEEEEEEEHSAEPRPR;MEVAEPS(0.444)S(0.444)PT(0.113)EEEEEEEEHSAEPRPR 75.225 6.425e-08 25429600.0 1071.5 1206.8 1734.35 1262.0 1909.9 2202.1800000000003 1295.7 2231.9 1736.2 1703.7 True False 1412.214711415466 1596.8744997397605 1711.3513857958415 971.0653977056369 1644.743352273732 2064.477336472829 1411.0147898965033 1887.0111389597694 1827.97198747745 1644.0539815659217 0.8589831764954369 0.971302960635621 1.0409338166413615 0.5906529886450081 1.0004193114797566 1.2557235708930092 0.8582533211911605 1.1477793065909168 1.111868593108087 1.0 10.683041954520421 -6.514160264559889 24.95424570736608 1.0768361127368653 0.8743079920313457 0.31679593079999424 0.1448483204528498 516.6372682002324 1478736.7076320343 0.0461906458309454 0.048517130851646786 3.060833707872211e-07 6.514160264559889 -0.20252812070551962 (ac)MEVAEPS(ph)SPTEEEEEEEEHSAEPRPR ddPTM_PC-9_Lapatinib_30min_R1 2 MEVAEPSSPTEEEEEEEEHSAEPRPR 26 1 M0R3H9;M0QXG9;M0R3F4;M0R2A4;M0R2K3;M0R193;M0R0I0;J3KQS6;Q9NWV8-3;Q9NWV8 M0R3H9 BABAM1 BRISC and BRCA1-A complex member 1 1 MEVAEPS(0.436)S(0.436)PT(0.128)EEEEEEEEHSAEPRPR;MEVAEPS(0.42)S(0.42)PT(0.16)EEEEEEEEHSAEPRPR 75.184 2.1039000000000002e-07 20679600.0 2036.31 2248.8 3527.4 3669.6 2568.5 3082.06 2955.3500000000004 2878.9 2171.1 1083.2 True False 2007.2718459864818 2243.5930417658606 3237.390788157763 3939.4746254267475 2417.4258798652922 2950.2474784327705 3108.3635623613936 3012.6642039411586 1926.5678553034504 1270.429676726726 1.5799944560160437 1.7660112030336848 2.5482644552974634 3.100899402457947 1.9028411600820068 2.3222438301615487 2.446702575753836 2.371374235922539 1.5164694989393435 1.0 10.311100803425628 -8.454822010882836 3.1805071045579276 1.008659892459841 2.272888663257867 0.5026614006957131 0.4110601495804179 0.1946852335318779 4.043911720612687 0.42104906723222785 0.1122295362872122 3.50895653838668e-09 8.454822010882836 1.264228770798026 (ac)MEVENEASCSPGS(ph)ASGGSR ddPTM_PC-9_AZD4547_30min_R2 2 MEVENEASCSPGSASGGSR 19 0 A0A3B3ITB4;K7EMR8;Q99578-2;Q99578 A0A3B3ITB4 RIT2 GTP-binding protein Rit2 1 MEVENEAS(0.003)CS(0.035)PGS(0.481)AS(0.481)GGS(0.001)R;MEVENEAS(0.002)CS(0.018)PGS(0.594)AS(0.386)GGS(0.001)R 49.483000000000004 0.027332 9787400.0 0.0 0.0 0.0 0.0 793.9 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 683.6806887115109 0.0 0.0 0.0 0.0 0.0 0.0 (ac)MEVKPPPGRPQPDS(ph)GR ddPTM_PC-9_AZD4547_30min_R2 2 MEVKPPPGRPQPDSGR 16 2 P51991 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 1 MEVKPPPGRPQPDS(1)GR;MEVKPPPGRPQPDS(1)GR 74.783 0.0014571 12749600.0 27314.5 29667.0 33322.0 32094.0 35258.0 33466.0 32691.0 40967.0 31517.0 34970.0 True False 35999.942823105666 39256.27758019513 32880.12850779199 24695.224147357145 30363.035297380593 31373.36572959508 35600.435669141465 34636.49147800748 33182.92427676926 33745.71094403961 1.066800544899002 1.1632968007488025 0.9743498532988975 0.7318033449735033 0.8997598345973954 0.9296993559158205 1.0549617913866902 1.0263968518975657 0.9833227200871953 1.0 15.042416527846845 -5.356266258135458 5.81223658775668 0.9430124985850509 1.1137877451348797 0.36532798630780416 0.08720633811730764 0.24145753812967868 11.843740492244175 0.02554421442425217 0.05439011395120781 4.4028485002239925e-06 5.356266258135458 0.17077524654982879 (ac)MEVKPPPGRPQPDS(ph)GR ddPTM_PC-9_Lapatinib_30min_R1 5 MEVKPPPGRPQPDSGR 16 2 P51991 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 1 MEVKPPPGRPQPDS(1)GR;MEVKPPPGRPQPDS(1)GR;MEVKPPPGRPQPDS(1)GR;MEVKPPPGRPQPDS(1)GR;MEVKPPPGRPQPDS(1)GR 71.929 6.5563e-05 49009200.0 133328.0 165666.0 179321.0 151918.0 166958.0 157911.0 152723.0 154525.0 169321.0 123996.0 True False 131426.71827063904 165282.4105554887 164577.91957907716 163090.55650359156 157137.8586920572 151157.51463852005 160630.24966062183 161704.79562124706 150250.28595082488 145428.54338571551 0.9037202409575136 1.1365197416377568 1.1316755001978693 1.1214480507518503 1.0805159360998717 1.039393719550706 1.1045304169387664 1.1119192412755077 1.0331554071357285 1.0 17.14995093048661 -8.482193859651893 4.818731485490466 1.0002162095040747 1.0832258549067488 0.13448292938726425 0.06488436811998623 0.3207896301632695 17.88626471038425 0.061046092834118056 0.015900429020975097 3.2946261437285737e-09 8.482193859651893 0.08300964540267408 (ac)MEVS(ph)PLQPVNENMQVNK ddPTM_PC-9_AZD4547_30min_R2 1 MEVSPLQPVNENMQVNK 17 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 MEVS(1)PLQPVNENMQVNK 120.96 4.3165e-05 14000000.0 19160.0 19375.0 29180.0 46631.0 31987.0 32187.0 32940.0 42847.0 37000.0 33339.0 True False 25252.481447242495 25637.58985122464 28793.054134126694 35880.94339176827 27546.157185810695 30174.341801783194 35871.59618676454 36225.980676109706 38955.74446300289 32171.811757601845 0.7849256870426519 0.7968960543593495 0.8949777013202626 1.1152913507673374 0.8562202649125548 0.9379124193915914 1.115000810555485 1.1260161830192825 1.2108657341561773 1.0 14.973509563289792 -5.251471372946384 0.41066068571218295 1.1212126394512867 0.6036736986715691 0.563309332326457 0.09514653781456463 2.9606608674190897 0.5233860869769343 0.08593631462852462 0.7253018994117219 5.60439358194576e-06 5.251471372946384 -0.5175389407797176 (ac)MEVS(ph)PLQPVNENMQVNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MEVSPLQPVNENMQVNK 17 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 MEVS(1)PLQPVNENMQVNK;MEVS(1)PLQPVNENMQVNK 83.226 0.00072677 10498600.0 33897.0 30345.0 33638.0 34343.0 37803.0 32944.0 39375.0 39367.0 35591.0 28364.0 True False 39635.09260373272 33357.4510568815 34440.057492825385 32418.87305150827 30395.773521106123 31216.35864540251 35645.11494968658 38333.657962784346 36111.45104344319 33506.16867069955 1.1829192705757727 0.995561485549731 1.0278721459115228 0.9675493897891674 0.9071694773531834 0.9316600460111861 1.063837387676541 1.1440776276013418 1.0777553052498627 1.0 15.03213910769754 -10.008090980196858 9.55437778463299 0.9999999986323305 1.0274392343714174 0.009851848362121052 0.0835923011578399 0.0 0.0 0.08795931110143734 0.02133326633680715 9.815422985328268e-11 10.008090980196858 0.02743923573908691 (ac)MEVS(ph)PLQPVNENMQVNK ddPTM_PC-9_Lapatinib_30min_R1 2 MEVSPLQPVNENMQVNK 17 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 MEVS(1)PLQPVNENMQVNK;MEVS(1)PLQPVNENMQVNK 84.821 0.0007971 0.0 12836.099999999999 13439.5 14027.599999999999 12189.4 12402.099999999999 12885.2 14734.1 12235.9 14095.0 9998.8 True False 12653.054860147553 13408.381663470414 12874.304876101896 13085.849138646387 11672.632861466744 12334.130032868257 15496.95960349502 12804.424583349075 12507.472673069946 11727.079257436466 1.0789604625656384 1.1433692370560034 1.0978270542460897 1.115866009888889 0.9953572074704623 1.0517648735977327 1.3214679685624167 1.0918681712865064 1.066546272818836 1.0 13.5175561204943 (ac)MFCVT(ph)PPELETK ddPTM_PC-9_AZD4547_30min_R2 1 MFCVTPPELETK 12 0 O60256;O60256-2;O60256-3;E7EPA1;C9K0K7;C9JDU5;C9JJS3;I3L1T1;I3L275;E7EW35;I3L164;I3L331;I3L2J4;I3L3B8;C9JDH0 O60256 PRPSAP2 Phosphoribosyl pyrophosphate synthase-associated protein 2 1 MFCVT(1)PPELETK 83.53 0.0013802999999999999 0.0 10693.0 11332.0 17042.0 19739.0 17713.0 16154.0 12967.0 15869.0 13931.0 13598.0 True False 14093.151571783088 14994.847390662055 16816.01194495501 15188.478514509956 15253.855698635845 15143.887826327575 14121.037879592466 13416.810683342703 14667.364219299816 13121.93815890907 1.074014478738769 1.1427311429966909 1.2815189144553214 1.1574874329214713 1.162469713994142 1.1540892544174743 1.0761396455755328 1.0224717203253568 1.117774222197617 1.0 13.679693206649798 -7.28874072967378 2.9176822702369964 1.0515772921287279 1.1681557638906466 0.48296628833303157 0.05519314622008866 0.24712667210449477 4.22774179240412 0.025920125524089305 0.01725050677494393 5.143506231446757e-08 7.28874072967378 0.11657847176191871 (ac)MFPTGFS(ph)SPSPSAAAAAQEVR ddPTM_PC-9_AZD4547_30min_R2 1 MFPTGFSSPSPSAAAAAQEVR 21 0 A0A669KAX4;Q13620-1;A0A669KAU9 A0A669KAX4 CUL4B Cullin-4B 1 MFPT(0.078)GFS(0.758)S(0.161)PS(0.003)PSAAAAAQEVR 86.179 0.00018594 2646200.0 0.0 1024.2 1871.9 1327.1 1819.2 891.46 1516.8 2403.7 0.0 2333.5 True False 0.0 1355.2526206773814 1847.0773829222667 1021.15759849061 1566.6354816777684 835.716865275349 1651.7922615690486 2032.2633965310251 0.0 2251.804875262122 0.0 0.601851712626576 0.8202652917283773 0.4534840517084065 0.6957243493379521 0.37113200813106295 0.7335414714282343 0.9025042173312015 0.0 1.0 11.13686610422591 -11.991734206040377 2.287673142262067 6.453685286257581 0.5386474365441675 0.18960862803910494 0.29898970099432404 9911181.43037896 600660.1927687759 285160819.4397845 0.07512939107925655 1.0192149702392233e-12 11.991734206040377 -5.915037849713414 (ac)MFPTGFS(ph)SPSPSAAAAAQEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MFPTGFSSPSPSAAAAAQEVR 21 0 A0A669KAX4;Q13620-1;A0A669KAU9 A0A669KAX4 CUL4B Cullin-4B 1 MFPT(0.022)GFS(0.411)S(0.411)PS(0.138)PS(0.019)AAAAAQEVR;MFPT(0.032)GFS(0.454)S(0.33)PS(0.153)PS(0.03)AAAAAQEVR 127.5 3.2895e-05 6059700.0 28176.0 35161.0 26363.0 27508.0 36962.0 29017.0 39592.0 19770.3 23755.1 24655.0 True False 32945.64029863329 38651.55170904633 26991.593902234257 25966.815942139292 29719.56143393709 27495.297438490925 35841.55913874261 19251.350573364376 24102.47339726607 29124.756331127377 1.131190246677611 1.3271030071327017 0.9267577587726191 0.8915719550376803 1.0204226636627345 0.9440524454827816 1.2306217683420266 0.6609961077267211 0.8275596582933917 1.0 14.829958359227279 -5.27238399105752 24.453439857945185 0.9376289854972806 1.2291466247806366 0.3966013250965964 0.14377146093300402 475.6810048949399 1062811.1317557504 0.0384176332507684 0.08125766450395305 5.340919214018378e-06 5.27238399105752 0.29151763928335606 (ac)MFPTGFSSPS(ph)PSAAAAAQEVR ddPTM_PC-9_Lapatinib_30min_R1 1 MFPTGFSSPSPSAAAAAQEVR 21 0 A0A669KAX4;Q13620-1;A0A669KAU9 A0A669KAX4 CUL4B Cullin-4B 1 MFPT(0.003)GFS(0.002)S(0.029)PS(0.863)PS(0.103)AAAAAQEVR 138.28 0.00021247 2072200.0 862.32 674.28 2428.5 843.77 1425.0 1613.7 1378.8 0.0 0.0 723.87 True False 850.0231586698793 672.7187460876398 2228.838104281094 905.823660534207 1341.184301657793 1544.6858127184282 1450.187517479787 0.0 0.0 848.9899650038545 1.0012169680545282 0.7923753799429014 2.625282036485525 1.066942717668158 1.5797410534195229 1.819439423776246 1.7081326956240324 0.0 0.0 1.0 9.729603691109299 -7.759602459149136 24.999966492267184 0.24999981662019752 1.5255066796916696 0.48819721548667194 0.5515740486759817 37.88170470914295 515583.8290454264 0.2738681183448512 0.1476786472385978 1.7393922906172687e-08 7.759602459149136 1.275506863071472 (ac)MGPPGS(ph)S(ph)PT(ph)PEPPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MGPPGSSPTPEPPQK 15 0 Q969S2-3 Q969S2-3 3 MGPPGS(1)S(1)PT(1)PEPPQK 57.53 0.032686 6189200.0 9866.5 8613.6 11789.0 12026.0 9418.3 15908.0 9843.6 12617.0 11104.0 9371.2 True False 11536.70357774225 9468.701282700751 12070.094470031467 11352.222208818057 7572.851724832251 15073.756475566504 8911.142946507543 12285.817118816522 11266.374993295862 11070.124377621612 1.0421476023398466 0.8553382924804208 1.0903305200826203 1.0254828059354697 0.6840800939997441 1.3616609860353766 0.8049722516687821 1.1098174419478473 1.0177279503806635 1.0 13.434383811060952 -6.743691257706358 24.999976734394327 1.049833058227167 0.9479607012197169 0.11151807792432733 0.16663365687420603 657.626855498883 926330.367061339 0.05257815749032174 0.05247210520592032 1.804299971631492e-07 6.743691257706358 -0.10187235700745023 (ac)MHRDS(ph)CPLDCK ddPTM_PC-9_Lapatinib_30min_R1 4 MHRDSCPLDCK 11 1 A0A087X2D0;P84103-2;P84103 A0A087X2D0 SRSF3 Serine/arginine-rich splicing factor 3 1 MHRDS(1)CPLDCK;MHRDS(1)CPLDCK;MHRDS(1)CPLDCK;MHRDS(1)CPLDCK 72.891 0.009170600000000001 23018400.0 90564.8 140698.0 185675.0 161763.0 164986.0 156934.0 160166.0 150903.0 165827.0 145720.0 True False 89273.32934444977 140372.2224254593 170409.51822622673 173659.59064554932 155281.84785495608 150222.29865102188 168458.61178174324 157914.50427848543 147149.8170242758 170907.50784030525 0.5223487866189361 0.8213344410628356 0.9970862039920222 1.0161027613123679 0.9085724191827215 0.8789683996292809 0.9856712201265597 0.9239764026401907 0.860990946996732 1.0 17.38285624936814 -4.811353051583826 2.803779546811641 0.943200396123653 0.46046481972749553 0.8616212834902377 0.0514029868825056 0.13889043386330674 1.584144457319528 0.013786179106231684 0.15170995670442347 1.5439987642744774e-05 4.811353051583826 -0.4827355763961575 (ac)MIAT(ph)GGLLR ddPTM_PC-9_AZD4547_30min_R2 1 MIATGGLLR 9 0 A6NKL6 A6NKL6 TMEM200C Transmembrane protein 200C 1 MIAT(1)GGLLR 68.37100000000001 0.033998 0.0 7742.7 7088.5 10161.0 14837.0 12939.0 12474.0 10063.0 12779.0 8017.7 10533.0 True False 10204.717541835302 9379.719001827394 10026.258500920541 11416.558879364926 11142.643193397462 11693.99880807294 10958.587505385905 10804.299182206594 8441.499253541037 10164.242875995682 1.0039820640192696 0.9228153160309605 0.9864245299174216 1.1232079967635138 1.096259045492942 1.1505036775232906 1.078150890241533 1.0629713707178816 0.830509400112511 1.0 13.311215133863676 -5.575351204529622 8.803136944804073 1.0587261225178406 0.9611955021212676 0.1442076218315419 0.08557035524984065 0.47283635458721623 73.27859909708218 0.02391100035211063 0.04155370316112522 2.6585742589123335e-06 5.575351204529622 -0.09753062039657301 (ac)MILLAGEITS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 MILLAGEITSR 11 0 P31153-2 P31153-2 MAT2A S-adenosylmethionine synthase isoform type-2 1 MILLAGEIT(0.178)S(0.822)R 51.251999999999995 0.011134 2680500.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)MIPLEKPGS(ph)GGSSPGATSGSGR ddPTM_PC-9_AZD4547_30min_R2 1 MIPLEKPGSGGSSPGATSGSGR 22 1 Q9UEE5 Q9UEE5 STK17A Serine/threonine-protein kinase 17A 1 MIPLEKPGS(0.745)GGS(0.193)S(0.062)PGATSGSGR 92.133 0.00036661 0.0 6827.3 7518.0 12954.0 14928.0 9573.3 10332.0 9272.7 10103.0 7430.8 11791.0 True False 8998.239383338134 9948.046477497117 12782.221496006754 11486.58023530091 8244.212542186557 9685.938406686673 10097.95233639987 8541.813493844058 7823.5769177211405 11378.200678901087 0.7908314888507653 0.8743075252613584 1.12339568062894 1.0095251929068885 0.7245620616864342 0.85127153932586 0.8874823551956491 0.7507174231584244 0.6875935078407095 1.0 13.47398481093138 -6.253667135410884 24.90325388900876 0.8097175982695464 0.9565630629880806 0.23654501278751305 0.11597383734495352 819.1488930669881 2624654.6948966472 0.03575653108916682 0.04528949277088099 5.576129671143617e-07 6.253667135410884 0.1468454647185342 (ac)MIPLEKPGS(ph)GGSSPGATSGSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MIPLEKPGSGGSSPGATSGSGR 22 1 Q9UEE5 Q9UEE5 STK17A Serine/threonine-protein kinase 17A 1 MIPLEKPGS(0.541)GGS(0.227)S(0.227)PGAT(0.004)S(0.001)GSGR 70.414 0.00053798 0.0 11948.0 11364.0 11527.0 16408.0 19723.0 15984.0 12823.0 17447.0 17765.0 8780.8 True False 13970.560416243286 12492.142817940394 11801.847396390942 15488.712955453735 15858.41973274015 15145.77090177615 11608.31260951951 16989.034736624537 18024.77951692192 10372.689531225442 1.3468599801610748 1.2043301576061496 1.137780838890746 1.493220529625153 1.528862855193027 1.4601585110768094 1.1191227284470828 1.6378620689919976 1.7377151280447563 1.0 13.340502398124247 -5.768058942693146 24.999806456538487 1.4448679998169114 1.2271242998222596 0.14457106664375774 0.21435696755125225 265.9025294345985 1004225.483734501 0.059866009899413646 0.09114901707329558 1.7058508542470285e-06 5.768058942693146 -0.21774369999465182 (ac)MIPLEKPGSGGS(ph)SPGATSGSGR ddPTM_PC-9_Lapatinib_30min_R1 1 MIPLEKPGSGGSSPGATSGSGR 22 1 Q9UEE5 Q9UEE5 STK17A Serine/threonine-protein kinase 17A 1 MIPLEKPGS(0.028)GGS(0.484)S(0.484)PGAT(0.003)S(0.001)GSGR 70.414 0.0025418000000000003 0.0 17481.0 12613.0 13319.0 12642.0 15186.0 14854.0 12388.0 9176.1 10264.0 10262.0 True False 17231.71773437722 12583.795373440404 12223.963232826794 13571.734852475714 14292.789336824733 14218.729046365217 13029.390025050468 9602.455104999986 9107.960235288387 12035.77302674452 1.431708432527505 1.0455327917432582 1.0156359052022748 1.1276163834527417 1.187525662461807 1.1813723152447275 1.082555312076594 0.7978262039058486 0.756740777268707 1.0 13.55504118492941 -7.671476207331177 4.417990247362707 0.8329080667820483 1.150336379160276 0.5680921752388874 0.12129696920474084 0.15293525232917726 5.344656205049749 0.06113660134906808 0.03327081916527421 2.1307072943870475e-08 7.671476207331177 0.3174283123782278 (ac)MIPLEKPGSGGSS(ph)PGATSGSGR ddPTM_PC-9_AZD4547_30min_R2 1 MIPLEKPGSGGSSPGATSGSGR 22 1 Q9UEE5 Q9UEE5 STK17A Serine/threonine-protein kinase 17A 1 MIPLEKPGS(0.18)GGS(0.18)S(0.635)PGAT(0.002)S(0.001)GS(0.002)GR 65.808 0.0011214999999999999 7307400.0 29035.0 23885.0 36304.0 53367.0 48005.0 34080.0 33795.0 39536.0 29488.0 32679.0 True False 38267.52603448256 31605.35915336774 35822.58523938777 41064.062661930846 41340.33437661683 31948.972212532135 36802.68953041006 33426.619646898806 31046.675479054873 31534.918156713462 1.2134969193295906 1.0022337459797492 1.135965695593902 1.302177556252472 1.3109383753962873 1.0131300184056613 1.1670456649837584 1.0599875186225152 0.9845173951226937 1.0 14.944662568504285 -7.849933564337053 1.2598988362405632 0.9851559583412208 1.1707827171326897 0.3457124939418542 0.09655608955156282 0.590563752912226 1.6934566758049547 0.09006215489488119 0.03324689017958797 1.4127536423404095e-08 7.849933564337053 0.18562675879146884 (ac)MKALFAQNQLDTQK ddPTM_PC-9_Lapatinib_30min_R1 1 MKALFAQNQLDTQK 14 1 A0A087WYA1;Q9UKN7;A0A2R8Y712;Q9UKN7-2 A0A087WYA1 MYO15A Unconventional myosin-XV 0 49.5 0.035805000000000003 0.0 0.0 572.36 2743.3 720.6 1090.4 2551.2 715.6 465.09 4652.9 0.0 False True 0.0 571.0347355856936 2517.7564634442333 773.5953278511313 1026.264815808882 2442.091123137668 752.6502665423089 486.69977929452034 4128.841404790859 0.0 0.0 (ac)MLGGS(ph)GSHGRR ddPTM_PC-9_AZD4547_30min_R2 1 MLGGSGSHGRR 11 1 E7EX44;Q05682-3;Q05682-5;E9PGZ1 E7EX44;Q05682-5 CALD1 Caldesmon 1 MLGGS(0.503)GS(0.497)HGRR 44.614 0.036297 1622200.0 2886.2 3195.4 3931.4 5339.3 4560.4 4751.7 3239.3 5596.1 4137.3 4761.0 True False 3803.9515633106093 4228.250560547259 3879.267067268873 4108.406876362682 3927.2671782340035 4454.575447837114 3527.591424644398 4731.351330585048 4355.989231534649 4594.318839135617 0.8279685621527938 0.9203215337450914 0.8443617439486905 0.8942363427993266 0.8548094539674757 0.969583436371866 0.7678159805966112 1.0298265088356848 0.9481251484832063 1.0 12.165635265818104 -7.784277461884238 24.99969726374619 0.9917319047599225 0.8738693386279532 0.5197489853013106 0.054537268222954405 189.89051977166096 207860.56366050383 0.027294902740091317 0.01312576027321549 1.6433215031863836e-08 7.784277461884238 -0.11786256613196922 (ac)MLGGS(ph)GSHGRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MLGGSGSHGRR 11 1 E7EX44;Q05682-3;Q05682-5;E9PGZ1 E7EX44;Q05682-5 CALD1 Caldesmon 1 MLGGS(0.5)GS(0.5)HGRR 55.258 0.005550800000000001 1660300.0 2510.9 2931.2 2611.0 2540.8 2642.8 3558.0 974.56 2121.1 3574.1 2227.5 True False 2935.945777464451 3222.190164374067 2673.256142272643 2398.447213384742 2124.962311498538 3371.4122164989717 882.2426215966103 2065.4233724912197 3626.3644509671076 2631.328117119702 1.1157657452002563 1.2245489809538208 1.0159341683312517 0.9114968208564292 0.8075626516029324 1.281258766082498 0.3352841539816512 0.7849356980808873 1.3781498504020053 1.0 11.361575443248082 -5.502657791359601 3.1421337685181485 0.9049184609742512 1.1689160148024669 0.10673976671255736 0.2701538813397802 0.5209514255250431 10.42229207447203 0.07548038535564734 0.16361350907686703 3.1429842784914656e-06 5.502657791359601 0.26399755382821566 (ac)MLGGSGS(ph)HGR ddPTM_PC-9_AZD4547_30min_R2 1 MLGGSGSHGR 10 0 E7EX44;Q05682-3;Q05682-5;E9PGZ1 E7EX44;Q05682-5 CALD1 Caldesmon 1 MLGGS(0.085)GS(0.915)HGR 52.79 0.032596 0.0 1720.7 0.0 3105.1 2375.1 5287.9 1897.1 1910.7 3183.1 2333.6 1724.7 True False 2267.846807216603 0.0 3063.9243451637017 1827.5573899292046 4553.766360798082 1778.4740371007833 2080.7485984836385 2691.2250353612794 2456.949331861178 1664.3187779578225 1.3626276631928231 0.0 1.8409480117284047 1.0980813376219198 2.736114271561433 1.068589780188044 1.2502103719798139 1.6170129611008217 1.4762492404705914 1.0 10.700716073509062 -5.277895668431103 24.984365226523895 1.5368438172398735 0.6813137189386791 0.2520666083998525 0.5702052044715081 893.2406795743863 1356140.6334249617 0.14225546167256695 0.29748080734921317 5.273565342879605e-06 5.277895668431103 -0.8555300983011944 (ac)MLGGSGS(ph)HGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MLGGSGSHGR 10 0 E7EX44;Q05682-3;Q05682-5;E9PGZ1 E7EX44;Q05682-5 CALD1 Caldesmon 1 MLGGS(0.216)GS(0.784)HGR 73.95100000000001 0.039786 1528000.0 1935.7 1169.4 4275.2 1424.3 4189.1 5371.3 1402.4 1001.1 2180.2 1792.8 True False 2263.375778182299 1285.4903037046372 4377.136981786289 1344.5010886429027 3368.2759267059646 5089.61957236676 1269.5545195032485 974.8221857531282 2212.0813004668257 2117.8204482030073 1.0687288339777798 0.606987388754032 2.066812125409562 0.6348513113015439 1.5904445202443775 2.403234691914206 0.5994627734284456 0.46029501064657063 1.0445084248496135 1.0 11.048364565461828 (ac)MLIGT(ph)PT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 MLIGTPTPR 9 0 P28062-2 P28062-2 PSMB8 Proteasome subunit beta type-8 2 MLIGT(1)PT(1)PR;MLIGT(1)PT(1)PR 48.504 0.029060000000000002 2243300.0 1373.54 0.0 0.0 580.64 0.0 0.0 0.0 0.0 0.0 0.0 True False 1353.953067723614 0.0 0.0 623.3422025582586 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)MLLS(ph)QGLGVLRVAWDSR ddPTM_PC-9_Lapatinib_30min_R1 2 MLLSQGLGVLRVAWDSR 17 1 Q6NUI2-5 Q6NUI2-5 1 MLLS(0.985)QGLGVLRVAWDS(0.015)R;MLLS(0.908)QGLGVLRVAWDS(0.092)R 58.172 0.0039857 6950900.0 15552.8 16853.6 19581.9 19903.5 22836.0 22692.0 16376.900000000001 19860.2 22864.0 13491.9 True False 15331.014219965795 16814.576524682092 17971.951770319913 21367.269786129622 21492.831377303406 21721.516057635614 17224.815749212885 20782.97739522463 20288.81555140625 15823.95693817329 0.9688483278781975 1.0626025203670175 1.1357432177387223 1.3503114214488154 1.3582463262052158 1.3726981274345615 1.0885277188577402 1.313386877658162 1.2821581625049834 1.0 13.949822784749987 -5.397213878892964 2.4723392720468818 1.266977386532254 1.002954562629545 0.38810520864349163 0.11745946564959259 0.2794074008673058 3.26316879285426 0.032133598269507575 0.08688502126377684 4.0066934965416575e-06 5.397213878892964 -0.2640228239027089 (ac)MLLVY(ph)DLY(ph)LSPK ddPTM_PC-9_Lapatinib_30min_R1 1 MLLVYDLYLSPK 12 0 Q9BRS8;K7EPD2 Q9BRS8 LARP6 La-related protein 6 2 MLLVY(0.967)DLY(0.895)LS(0.138)PK 43.958 0.034599 2077200.0 7965.1 5694.9 11763.0 6290.0 9267.1 10355.0 7049.2 7773.0 16000.0 10408.0 True False 7851.516213379554 5681.713808943613 10795.891546493096 6752.5875828248945 8722.027397819602 9912.140788683973 7414.173083999502 8134.161956731606 14197.911512530616 12207.00893221175 0.6431973841406015 0.46544684619266197 0.8844010524154685 0.5531729861363683 0.714509790748493 0.8120040579742596 0.6073701694798507 0.6663517657685373 1.16309503756201 1.0 13.575422121455789 -8.254687591791134 24.85499978332898 1.0815475314699767 0.6692088885951192 0.6587403685549533 0.11897159326427048 252.35548352727724 928992.0731623581 0.08182752926926683 0.029350822099473133 5.563042889071065e-09 8.254687591791134 -0.41233864287485755 (ac)MLNTVSKIR ddPTM_PC-9_AZD4547_30min_R2 1 MLNTVSKIR 9 1 Q99963-2 Q99963-2 0 52.482 0.021189 3998200.0 60056.0 48399.0 46699.0 59710.0 64715.0 66016.0 52117.0 50434.0 74625.0 86647.0 False True 79152.55875759874 64043.030255970116 46079.74074741543 45944.78201030392 55730.439312212446 61888.00908399422 56755.31203599298 42640.584158025435 78569.52515004306 83613.51490329436 0.9466479055347086 0.7659411320052858 0.5511039788329709 0.5494899008066183 0.6665242978562629 0.7401675333894597 0.678781559436115 0.5099723915128151 0.9396749465790899 1.0 16.351448531282664 -8.403787947932267 5.990393923248573 0.996861625129556 0.6731920219067948 0.48974710161123125 0.12050939372050773 0.19301447463833954 8.10125435748171 0.12154861641118636 0.03152611595578327 3.946499499537386e-09 8.403787947932267 -0.32366960322276117 (ac)MNGSNMANTS(ph)PSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MNGSNMANTSPSVK 14 0 Q9ULR5 Q9ULR5 PAIP2B Polyadenylate-binding protein-interacting protein 2B 1 MNGSNMANT(0.092)S(0.84)PS(0.068)VK 64.798 0.0095332 1694600.0 6445.1 6972.1 8168.3 6193.0 9107.0 9935.2 6976.2 8863.4 9124.0 7270.1 True False 7536.128133472512 7664.244010996327 8363.06325045026 5846.026287976896 7322.548725146508 9414.180622079986 6315.363832685804 8630.745141548574 9257.421239087853 8588.111579920062 0.8775070122624861 0.8924248293322321 0.9737953649791894 0.680711496767874 0.8526378188037779 1.0961875069359095 0.735361176192891 1.0049642533439125 1.0779344391301005 1.0 13.068125220007772 -7.97703703908682 24.578765283301 1.0397946450561806 0.8772127355872948 0.29868497217763124 0.10949266420406317 222.67223977006975 238340.53905308913 0.05952184876717438 0.028590431470262852 1.054296976154831e-08 7.97703703908682 -0.16258190946888573 (ac)MNLLPNIES(ph)PVTR ddPTM_PC-9_AZD4547_30min_R2 6 MNLLPNIESPVTR 13 0 E9PM69;P17980 E9PM69 PSMC3 26S protease regulatory subunit 6A 1 MNLLPNIES(0.917)PVT(0.083)R;MNLLPNIES(0.918)PVT(0.082)R;MNLLPNIES(0.952)PVT(0.048)R;MNLLPNIES(0.786)PVT(0.214)R;MNLLPNIES(0.907)PVT(0.093)R;MNLLPNIES(0.884)PVT(0.116)R 141.85 0.00026851 21789700.0 3775.3999999999996 2924.11 6142.4 7057.6 3641.3700000000003 5581.37 3801.74 6048.17 3450.95 2697.5099999999998 True False 4975.898666801633 3869.2713734123595 6060.947762627139 5430.579358833047 3135.82863012147 5232.366051580411 4140.087495053744 5113.564299620195 3633.3601717459405 2603.0709959581413 1.9115493486454445 1.4864256024596647 2.328383579256246 2.0862202249824358 1.2046650417873948 2.0100742775378957 1.590462765511263 1.9644352027125516 1.3957975704034031 1.0 11.345998944894296 -9.18042930809221 0.5197815718903611 0.9431804869024619 1.8575697613875624 0.3938896864632314 0.3153114485399622 2.6168746619316527 1.1273600130880994 0.5990587457752948 0.15567814846430097 6.600406630667358e-10 9.18042930809221 0.9143892744851004 (ac)MNLLPNIES(ph)PVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 MNLLPNIESPVTR 13 0 E9PM69;P17980 E9PM69 PSMC3 26S protease regulatory subunit 6A 1 MNLLPNIES(0.837)PVT(0.163)R;MNLLPNIES(0.947)PVT(0.053)R;MNLLPNIES(0.987)PVT(0.013)R;MNLLPNIES(0.961)PVT(0.039)R;MNLLPNIES(0.762)PVT(0.238)R;MNLLPNIES(0.889)PVT(0.111)R 125.47 0.00013599 13190700.0 5633.93 5897.969999999999 6893.4400000000005 4924.51 8757.28 5540.27 7516.29 9083.33 6750.59 5334.85 True False 6587.6430738103045 6483.481483274192 7057.805753116784 4648.60567017683 7041.353848660483 5249.728488112077 6804.292597972818 8844.902212083667 6849.304607888428 6302.016074350637 1.0453231150301532 1.0287948184807278 1.1199282372258983 0.7376378630795265 1.1173176592359022 0.8330236588063625 1.0797009270837088 1.4035035943628644 1.0868434048851874 1.0 12.621597718858284 -7.525779631595039 24.991989734612982 1.195424572096441 0.9817699585929041 0.2299230759240516 0.14789005536703462 109.74324844737578 945436.3304412074 0.06533842236539993 0.03798918680932706 2.9800281628200366e-08 7.525779631595039 -0.21365461350353687 (ac)MNLLPNIES(ph)PVTR ddPTM_PC-9_Lapatinib_30min_R1 4 MNLLPNIESPVTR 13 0 E9PM69;P17980 E9PM69 PSMC3 26S protease regulatory subunit 6A 1 MNLLPNIES(0.976)PVT(0.024)R;MNLLPNIES(0.848)PVT(0.152)R;MNLLPNIES(0.891)PVT(0.109)R;MNLLPNIES(0.992)PVT(0.008)R 203.74 1.8479e-10 22650700.0 3056.5 1009.6 2779.83 1777.7 1254.23 2038.93 2753.43 1823.3600000000001 2967.43 3474.69 True False 3012.9137495065474 1007.2623332296386 2551.2831078541108 1908.4379882333558 1180.4586573110553 1951.7297168779744 2895.9891327635405 1908.0799621029387 2633.206784976794 4075.285536766605 0.7393135333277874 0.24716362182288118 0.626037877551603 0.46829552702889626 0.2896628093077496 0.4789185197625458 0.7106223862441952 0.4682076740116814 0.6461404388037117 1.0 11.992685430642702 -9.15219510724069 0.6146974375979696 1.0174886133578376 0.47382317678979546 0.49781045353063225 0.15099924134347384 1.790874727245984 1.0538025078586608 0.21594951376163848 0.060446618751038586 7.043765559865581e-10 9.15219510724069 -0.5436654365680421 (ac)MNNTAAS(ph)PMSTATSSSGR ddPTM_PC-9_AZD4547_30min_R2 1 MNNTAASPMSTATSSSGR 18 0 O75486 O75486 SUPT3H Transcription initiation protein SPT3 homolog 1 MNNT(0.004)AAS(0.989)PMS(0.006)T(0.001)ATSSSGR 91.589 2.11e-06 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)MNTAPS(ph)RPSPTR ddPTM_PC-9_Lapatinib_30min_R1 1 MNTAPSRPSPTR 12 1 Q9HCD5 Q9HCD5 NCOA5 Nuclear receptor coactivator 5 1 MNT(0.004)APS(0.447)RPS(0.447)PT(0.102)R 80.312 0.00063823 71873000.0 132350.0 74391.0 104160.0 95268.0 93913.0 95738.0 91255.0 107410.0 79895.0 79427.0 True False 130462.66472998234 74218.75221006927 95596.3668692275 102274.3265247318 88389.22198006205 91643.5089161783 95979.73738585584 112400.66071948338 70896.38376835213 93155.8511201749 1.400477405994392 0.7967159477113682 1.0261982013980444 1.0978840866666946 0.9488316720549984 0.98376546201005 1.0303135684095464 1.2065872338440864 0.761051323302203 1.0 16.507358767255845 -4.742797062200486 24.969727787329163 0.9952382233048835 1.4004787389857127 0.5020960641730792 0.12407896810384166 1046.5462505064618 1401681.6380854987 0.029480981521448943 1.0136154970690183 1.8080187824720237e-05 4.742797062200486 0.4052405156808292 (ac)MNTAPSRPS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 7 MNTAPSRPSPTR 12 1 Q9HCD5 Q9HCD5 NCOA5 Nuclear receptor coactivator 5 1 MNTAPS(0.074)RPS(0.699)PT(0.227)R;MNTAPS(0.109)RPS(0.703)PT(0.187)R;MNTAPS(0.02)RPS(0.837)PT(0.143)R;MNTAPS(0.002)RPS(0.499)PT(0.499)R;MNTAPS(0.029)RPS(0.486)PT(0.486)R;MNTAPS(0.001)RPS(0.753)PT(0.246)R;MNTAPS(0.01)RPS(0.745)PT(0.246)R 76.868 0.00015745 711948000.0 78978.8 66490.9 94877.79999999999 132921.8 133439.1 109422.6 91387.5 130068.6 80158.0 104576.0 True False 104092.41553890769 87982.78312458283 93619.65837994663 102278.73263133832 114913.38429152829 102580.38752414966 99520.81045895409 109969.48654908505 84394.98823419964 100914.82607045732 1.0314878357540034 0.8718519027437502 0.9277096540262845 1.0135154229957126 1.1387165668927317 1.0165046259162105 0.9861862159824767 1.0897257700499419 0.8362991992403201 1.0 16.622778620407452 -5.781312319874525 8.555371864467494 1.0198597454115346 0.9364573538466796 0.11803469025494673 0.08219491874294763 0.3337208097809398 120.4002548134621 0.022610212300242512 0.03456236330778375 1.6545796559980896e-06 5.781312319874525 -0.08340239156485496 (ac)MNTAPSRPS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 MNTAPSRPSPTR 12 1 Q9HCD5 Q9HCD5 NCOA5 Nuclear receptor coactivator 5 1 MNTAPS(0.031)RPS(0.852)PT(0.117)R;MNTAPS(0.008)RPS(0.758)PT(0.234)R;MNTAPS(0.017)RPS(0.797)PT(0.186)R 81.904 0.00085728 102504700.0 6879.3 7614.97 7939.2 8375.8 10675.44 7637.0199999999995 10179.609999999999 6485.3099999999995 6350.6 4593.21 True False 8043.829617631602 8370.933896016506 8128.500637583665 7906.531080709985 8583.664166287257 7236.5212269946505 9215.323646805808 6315.077484253941 6443.465510845163 5425.922613169645 1.4824814489812013 1.542766915934041 1.4980863563837787 1.4571772663177094 1.5819732012862167 1.333694146214023 1.6983883302055647 1.1638716462572034 1.1875336178230347 1.0 12.405652756094518 -7.856867660122904 7.184939468283685 1.122998620458421 1.5070554083430077 0.7737412419412698 0.09831797521484112 0.10067866960136901 6.496559358754372 0.05007681091151113 0.023906198912490732 1.3903762474398676e-08 7.856867660122904 0.38405678788458664 (ac)MNTAPSRPS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 2 MNTAPSRPSPTR 12 1 Q9HCD5 Q9HCD5 NCOA5 Nuclear receptor coactivator 5 1 MNTAPS(0.226)RPS(0.586)PT(0.189)R;MNTAPS(0.021)RPS(0.755)PT(0.224)R 81.789 0.00015596 22085000.0 14565.8 7326.6 12760.2 7462.9 8620.3 11364.5 10787.5 11568.3 17259.3 16099.9 True False 14358.089020959418 7309.63570784496 11711.10561179641 8011.746561504589 8113.270902161872 10878.466826943415 11346.023966357114 12105.805450155443 15315.375885513728 18882.74626323174 0.7603813990191309 0.38710660017066456 0.6202013970076025 0.4242892664985372 0.42966583298108163 0.5761061804937684 0.6008672577701241 0.6411040683064054 0.8110777782009202 1.0 14.204780981760743 -8.36357219571622 1.0350906158498214 1.000078844091225 0.5209892429043137 0.6789855320956788 0.10321534063068843 0.2739566565119206 0.6290201514279373 0.09313210823090996 0.03126906583003815 4.3294009118892645e-09 8.36357219571622 -0.47908960118691124 (ac)MNTAPSRPSPT(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MNTAPSRPSPTR 12 1 Q9HCD5 Q9HCD5 NCOA5 Nuclear receptor coactivator 5 1 MNTAPS(0.006)RPS(0.145)PT(0.849)R 74.78 0.0016343 1087900.0 803.07 1036.4 1043.7 991.88 2605.5 688.6 2038.0 1211.1 1078.2 942.75 True False 939.0138896444998 1139.286942671016 1068.5857662542924 936.3081793183478 2094.9709787382494 652.4886037889802 1844.9458861577452 1179.3099082665206 1093.966635246002 1113.6631121951061 0.84317589346534 1.0230086012505197 0.959523355449959 0.8407463343854681 1.8811532462531855 0.5858940613583586 1.6566463106793856 1.0589467275628983 0.9823137924445742 1.0 10.121097161980462 (ac)MNVDHEVNLLVEEIHR ddPTM_PC-9_AZD4547_30min_R2 1 MNVDHEVNLLVEEIHR 16 0 Q5SZC9;Q9P1F3 Q5SZC9 ABRACL Costars family protein ABRACL 0 73.833 1.4029e-05 854590.0 0.0 0.0 984.66 2512.8 947.1 547.2 599.49 787.64 886.83 0.0 False True 0.0 0.0 971.6027650345852 1933.512782372997 815.6115131360018 512.9834974969948 652.8434486339854 665.9283361666174 933.7060233006716 0.0 0.0 (ac)MPLSTAGILS(ph)SS(ph)S(ph)AASNR ddPTM_PC-9_AZD4547_30min_R2 1 MPLSTAGILSSSSAASNR 18 0 A0A087X182;Q9UL16 A0A087X182 CFAP45 Cilia- and flagella-associated protein 45 3 MPLS(0.008)T(0.012)AGILS(0.635)S(0.639)S(0.711)S(0.933)AAS(0.062)NR 43.501999999999995 0.035363 0.0 609.97 767.11 4444.5 3396.9 1672.2 1781.6 1285.4 3818.4 1421.6 1833.8 True False 803.9277718358296 1015.063305846344 4385.5630260152875 2613.7971865818345 1440.0438942730689 1670.1962703593674 1399.7981098502478 3228.354018102954 1496.7428737460798 1769.599220165278 0.4542993479397804 0.5736119762482369 2.478280378992076 1.4770560230794574 0.8137683820512596 0.9438274222359645 0.7910255010846516 1.824341908221134 0.8458089587122931 1.0 10.789206939574326 -5.035910699540009 24.9994942660313 1.280807952381544 0.4841251874681007 0.26166294168350634 0.5107267545173034 674.4601037770063 469530.8502032876 0.1338049572052895 0.35431617059895787 9.206388558101147e-06 5.035910699540009 -0.7966827649134434 (ac)MQT(ph)PVNIPVPVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MQTPVNIPVPVLR 13 0 Q9H840 Q9H840 GEMIN7 Gem-associated protein 7 1 MQT(1)PVNIPVPVLR 84.365 0.0021204 0.0 4916.6 3487.4 3994.5 4379.6 3728.9 6303.7 4699.2 4560.3 5165.0 2015.7 True False 5748.883272723609 3833.6060245763238 4089.7440292256083 4134.225210854778 2998.2488131326245 5973.122874970365 4254.057756738213 4440.59695703725 5240.5283537800005 2381.1304537275805 2.4143504039116896 1.6099941179513877 1.7175640346891747 1.7362447338333715 1.2591703274547457 2.5085239935592942 1.7865706392014884 1.8649112441889284 2.2008573052249734 1.0 11.217430947601375 -6.737579692449946 24.999979833846048 1.920880365036915 1.7375434082345544 0.013111646249566067 0.4468202571315251 929.0577447358434 973456.8439265661 0.14044640401692635 0.1403748145181535 1.8298702967775645e-07 6.737579692449946 -0.18333695680236062 (ac)MQT(ph)PVNIPVPVLR ddPTM_PC-9_Lapatinib_30min_R1 1 MQTPVNIPVPVLR 13 0 Q9H840 Q9H840 GEMIN7 Gem-associated protein 7 1 MQT(1)PVNIPVPVLR 80.17 0.010847 1186800.0 3941.8 3370.0 5676.6 3141.1 4769.0 6378.9 5963.3 6628.7 6803.5 4415.8 True False 3885.589209162409 3362.196972052182 5209.89186030968 3372.1069724024287 4488.496796214746 6106.089316942171 6272.050495349009 6936.693601259082 6037.218185968878 5179.065146316357 0.7502491471701335 0.6491899362269204 1.0059521772988798 0.6511034090391509 0.8666615826231144 1.1789944988981584 1.211039119639197 1.3393717602090505 1.1656965138318232 1.0 12.338475990587195 -6.711417396595675 3.5703482838650262 1.206960317620397 0.7715252740936175 0.7269285616248029 0.12153239841852657 0.11439555120848624 2.985565832502265 0.04148485367782589 0.03991633319608423 1.9434913113812483e-07 6.711417396595675 -0.4354350435267794 (ac)MRS(ph)RVAVRACHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MRSRVAVRACHK 12 3 Q9UHN1 Q9UHN1 POLG2 DNA polymerase subunit gamma-2, mitochondrial 1 MRS(1)RVAVRACHK 43.419 0.024562999999999998 0.0 979.37 1018.5 6824.2 1229.5 6979.0 4381.1 2314.4 3154.4 3811.7 1040.5 True False 1145.157997560779 1119.6099489679953 6986.914808922624 1160.6151010927813 5611.515049170689 4151.347403514237 2095.1632771950362 3071.6003423630686 3867.438901472066 1229.134413406532 0.9316784113032737 0.9108930128032205 5.684418833867379 0.9442540119563895 4.565420175339846 3.377456003374623 1.704584343536778 2.4989946655631936 3.1464735339672925 1.0 10.263426976574133 -5.1004784682593955 22.06166691296517 2.9150503243783845 0.9174131629831648 0.23286862305868028 1.4089298381788753 17.601297142852705 3855.217094313462 0.335855281089251 0.8885936713773354 7.934535941718616e-06 5.1004784682593955 -1.9976371613952197 (ac)MRT(ph)VPQFT(ph)TFAATR ddPTM_PC-9_AZD4547_30min_R2 1 MRTVPQFTTFAATR 14 1 Q9BQ52-3 Q9BQ52-3 ELAC2 Zinc phosphodiesterase ELAC protein 2 2 MRT(1)VPQFT(0.458)T(0.458)FAAT(0.084)R 67.252 0.026902 2977600.0 2554.7 3248.7 4305.5 6207.3 4369.6 4269.6 3828.0 5628.5 5103.0 4339.1 True False 3367.0414589389534 4298.778743208952 4248.406256836275 4776.302886829 3762.956464786269 4002.6212370489206 4168.68458418138 4758.7446550629775 5372.7341620190255 4187.189429719249 0.8041292412138883 1.0266501708037565 1.0146200280986883 1.1406942453877114 0.8986831209684666 0.9559207445069654 0.9955806046398264 1.136500923814677 1.2831361590390877 1.0 12.031766472177756 -7.776307314314895 4.5338356522647505 1.1619394904786713 0.9815362263272841 0.33673732496633246 0.10415565533002788 0.21328710851085433 10.587619734182361 0.05645256349720427 0.027761036443429296 1.6737580766115366e-08 7.776307314314895 -0.1804032641513872 (ac)MRT(ph)VPQFT(ph)TFAATR ddPTM_PC-9_Lapatinib_30min_R1 2 MRTVPQFTTFAATR 14 1 Q9BQ52-3 Q9BQ52-3 ELAC2 Zinc phosphodiesterase ELAC protein 2 2 MRT(1)VPQFT(0.576)T(0.212)FAAT(0.212)R;MRT(1)VPQFT(0.474)T(0.474)FAAT(0.053)R 58.754 0.032999 4025600.0 4488.7 7178.1 7364.7 6205.2 8077.4 9662.8 9754.4 9569.7 11194.2 7571.700000000001 True False 4424.690314873236 7161.479550471149 6759.202794564116 6661.551107940381 7602.303212779402 9249.544569086967 10259.435103354243 10014.34319790744 9933.391315848143 8880.458256343938 0.49825022393550106 0.806431306104637 0.7611322073087321 0.7501359632180654 0.856071048737664 1.0415616291512169 1.1552821720686772 1.127683156525564 1.1185674240123837 1.0 13.116418410234838 -6.598768542223214 1.507722708510827 1.1164648341193344 0.7011384611723307 0.823020682429412 0.08490482627112937 0.15518641621002607 0.7279677689857929 0.03501095938092038 0.03632501923123369 2.5190190843856413e-07 6.598768542223214 -0.4153263729470037 (ac)MS(ph)GDEMIFDPTMSK ddPTM_PC-9_AZD4547_30min_R2 1 MSGDEMIFDPTMSK 14 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 MS(0.995)GDEMIFDPT(0.004)MS(0.001)K 46.843999999999994 0.0040877 0.0 4228.2 5518.8 7546.1 8077.2 8331.6 6771.6 5425.4 7345.8 4874.1 6953.5 True False 5572.67964797655 7302.644173983922 7446.033783465851 6215.126331496011 7174.901153884401 6348.170781525313 5908.250089607537 6210.67539969115 5131.734975327634 6710.060081480674 0.8304962370391854 1.0883127848793397 1.109682132953834 0.9262400419706154 1.0692752474283587 0.9460676513233984 0.8805062872557461 0.9255767197721831 0.7647822691619239 1.0 12.712109968951355 -7.01009661049467 4.479783088609913 0.8885004256754749 1.011209744337324 0.23804891212872203 0.09392497922352552 0.27187558541694473 13.759833408182978 0.03466960955820656 0.028355617997228626 9.770198549174418e-08 7.01009661049467 0.12270931866184909 (ac)MS(ph)GDEMIFDPTMSK ddPTM_PC-9_Lapatinib_30min_R1 1 MSGDEMIFDPTMSK 14 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 MS(0.998)GDEMIFDPT(0.002)MSK 43.083999999999996 0.03847 0.0 6194.4 5924.9 8702.5 6675.5 6248.6 7444.5 6835.7 7173.9 7712.7 5625.9 True False 6106.066720086164 5911.181258074773 7987.0140426214575 7166.438538815196 5881.0696332202715 7126.116088977098 7189.6190986630245 7507.225583609534 6844.014507668429 6598.32931895946 0.9253958729433462 0.8958602961949391 1.210460050799797 1.0860989490511403 0.8912967736123395 1.0799879400534178 1.0896120443707726 1.137746423483059 1.0372344538795637 1.0 12.68788506847177 (ac)MS(ph)PTPPLFSLPEAR ddPTM_PC-9_AZD4547_30min_R2 6 MSPTPPLFSLPEAR 14 0 A0A087WWS1;Q96FV9;J3KRD7;J3QQZ3;J3KT14;Q96FV9-2 A0A087WWS1 THOC1 THO complex subunit 1 1 MS(0.973)PT(0.027)PPLFSLPEAR;MS(0.948)PT(0.052)PPLFSLPEAR;MS(0.983)PT(0.017)PPLFSLPEAR;MS(0.87)PT(0.13)PPLFSLPEAR;MS(0.978)PT(0.022)PPLFSLPEAR;MS(1)PTPPLFSLPEAR 120.06 0.00010037 20930640.0 2128.65 897.64 1384.56 2740.4 3944.3799999999997 3663.84 2428.7 3641.06 1438.67 2418.33 True False 2805.516421329472 1187.7845756930722 1366.1998297445666 2108.6431187579456 3396.770921954792 3434.739505609264 2644.8495949846724 3078.4178402351627 1514.7151590969838 2333.665002782365 1.202193295946304 0.5089781842196327 0.5854309972149747 0.903575755836364 1.4555520684866572 1.4718220059494909 1.1333458709074742 1.3191344244203214 0.6490713779788575 1.0 11.188381761940567 -6.0359765309176 7.2393256058936775 1.1996444745551544 0.7399138119553897 0.29942361696638475 0.28146546490450947 0.2494368855360856 41.77448102142377 0.0830021881717601 0.10995002995616786 9.204993137863748e-07 6.0359765309176 -0.4597306625997647 (ac)MS(ph)PTPPLFSLPEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 MSPTPPLFSLPEAR 14 0 A0A087WWS1;Q96FV9;J3KRD7;J3QQZ3;J3KT14;Q96FV9-2 A0A087WWS1 THOC1 THO complex subunit 1 1 MS(0.993)PT(0.007)PPLFSLPEAR;MS(0.659)PT(0.341)PPLFSLPEAR;MS(0.995)PT(0.005)PPLFSLPEAR;MS(0.911)PT(0.089)PPLFSLPEAR 124.42 4.6233e-05 10724500.0 1021.4499999999999 1077.57 2831.4300000000003 1772.17 2803.13 2667.7 2561.85 1712.0 1741.5900000000001 1861.1799999999998 True False 1194.361310442894 1184.5440281879653 2898.942029458074 1672.8810603526601 2253.8767989370735 2527.801115782548 2319.1730218121766 1667.0618140139397 1767.0574589854227 2198.597200907226 0.5432378927572792 0.5387726445295103 1.3185416720542802 0.7608856500237355 1.025143122172191 1.1497336186635185 1.0548421606537097 0.7582388503569666 0.803720416935065 1.0 11.102367600777322 -5.224052319701364 24.12969430287653 0.9772199870707902 0.5410047041542211 0.5282327412671044 0.16732231862016542 296.27980199838123 191218.103402493 0.04299200412781856 0.11373821361267665 5.96963365738136e-06 5.224052319701364 -0.4362152829165691 (ac)MS(ph)PTPPLFSLPEAR ddPTM_PC-9_Lapatinib_30min_R1 6 MSPTPPLFSLPEAR 14 0 A0A087WWS1;Q96FV9;J3KRD7;J3QQZ3;J3KT14;Q96FV9-2 A0A087WWS1 THOC1 THO complex subunit 1 1 MS(0.905)PT(0.095)PPLFSLPEAR;MS(0.988)PT(0.012)PPLFSLPEAR;MS(0.997)PT(0.003)PPLFSLPEAR;MS(0.967)PT(0.033)PPLFSLPEAR;MS(1)PTPPLFSLPEAR;MS(0.886)PT(0.113)PPLFSLPEAR 136.02 0.00021832 21054680.0 1350.42 688.24 1703.98 1332.9299999999998 2398.59 799.75 2394.46 455.98 1767.6800000000003 681.7 True False 1331.1627631633025 686.6464225653392 1563.885341953015 1430.9581187241315 2257.50965200938 765.5465568083063 2518.433422617238 477.16649543682996 1568.585263904383 799.530936691847 1.6649296507163869 0.858811574454416 1.9560035393049005 1.7897470292330255 2.823542590296869 0.9574946029929059 3.14988864975951 0.5968080452410788 1.9618818883914466 1.0 9.64301004755589 -5.280275528408847 24.14820217516233 1.8222707319583382 1.2618705039881917 0.0639887633333388 0.7780865869235253 1188.2403953797145 1523340.2624028071 0.19103292377589381 0.3988926559537647 5.2447461350342575e-06 5.280275528408847 -0.5604002279701465 (ac)MSETELEK ddPTM_PC-9_AZD4547_30min_R2 2 MSETELEK 8 0 A0A1B0GVS7;A0A1B0GVS7-2 A0A1B0GVS7 0 ; 88.029 0.010137 11090800.0 946.16 585.05 1085.8 3427.64 3005.4 1419.55 1095.6 2183.8 1181.7 1787.42 False True 1247.0191986494226 774.1559712236889 1071.4015825508832 2637.4505545100997 2588.152086980193 1330.7853140933087 1193.106277541568 1846.3438887317295 1244.162249511636 1724.8429698483067 0.7229754942614244 0.44882692787493167 0.621158912016848 1.5290960398221372 1.5005146162423186 0.7715399821065139 0.6917187815923308 1.0704417277441252 0.7213191410816112 1.0 10.752249309200293 -5.560517647937155 24.996379207981953 1.0399372446246924 0.5731733988132464 0.3440702356227988 0.28047223503357693 185.64929924009743 123290.7769299494 0.08328376053856089 0.14425206584203837 2.750947815541939e-06 5.560517647937155 -0.46676384581144603 (ac)MSETELEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 MSETELEK 8 0 A0A1B0GVS7;A0A1B0GVS7-2 A0A1B0GVS7 0 ;;;;; 97.071 0.0079959 27162100.0 427.63 506.45 925.05 0.0 439.75 482.43 0.0 0.0 1047.99 0.0 False True 500.01931292250686 556.727008988553 947.1067002716604 0.0 353.5841442717883 457.1305215305227 0.0 0.0 1063.314871147707 0.0 0.0 (ac)MSETELEK ddPTM_PC-9_Lapatinib_30min_R1 1 MSETELEK 8 0 A0A1B0GVS7;A0A1B0GVS7-2 A0A1B0GVS7 0 97.071 0.010137 1694700.0 0.0 0.0 509.57 428.85 0.0 564.52 0.0 0.0 836.64 0.0 False True 0.0 0.0 467.6751215970833 460.38905960166215 0.0 540.3767955603937 0.0 0.0 742.4087929902257 0.0 0.0 (ac)MSLPS(ph)S(ph)CEYLTLGK ddPTM_PC-9_Lapatinib_30min_R1 1 MSLPSSCEYLTLGK 14 0 A0A1B0GW84 A0A1B0GW84 2 MS(0.022)LPS(0.886)S(0.543)CEY(0.549)LT(0.001)LGK 53.123999999999995 0.007728100000000001 6653200.0 9590.0 22615.0 32855.0 28928.0 34030.0 24367.0 19445.0 18182.0 28443.0 17851.0 True False 9453.244841409385 22562.636356961466 30153.788723967595 31055.4616209791 32028.42230555417 23324.880212251326 20451.76695488427 19026.802096654334 25239.449821931757 20936.52156503766 0.4515193611337787 1.0776688136504629 1.4402482585417649 1.4833152453003116 1.5297871810300672 1.1140761916822914 0.9768464590143336 0.9087852553514713 1.2055225956961089 1.0 14.353734149529537 -10.818986714690151 2.901333494568617 0.9986558189249027 1.1498245742346533 0.013654712121839774 0.3041663611462462 39772049.67761444 50535636.21473615 472439.49703904445 0.08102191519602403 1.5170967755840062e-11 10.818986714690151 0.1511687553097506 (ac)MT(ph)DEPFQNVT(ph)LDAY(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 MTDEPFQNVTLDAYK 15 0 D6REY0 D6REY0 NPY1R 3 MT(1)DEPFQNVT(1)LDAY(1)K 40.236999999999995 0.045125 0.0 13383.0 7950.0 10446.0 6871.9 8207.2 10631.0 10537.0 4947.8 11937.0 8621.4 True False 13192.15596585838 7931.592263446544 9587.17020272608 7377.282449986386 7724.468631976028 10176.336912071407 11082.55430206304 5177.692850831936 10592.529357817373 10111.597502706605 1.304655961862326 0.7844054573299094 0.9481360586356261 0.7295862447068017 0.7639216879339188 1.0064024907387257 1.0960240752360382 0.5120548804920296 1.047562400993714 1.0 13.303723322108457 -4.75485896128024 24.939352243406745 0.8662626591681172 1.3046567238215316 0.3603968162413036 0.1706475698159801 233.02706562389972 883073.8256392392 0.04094997207775888 0.3827604584004583 1.7584945987848575e-05 4.75485896128024 0.43839406465341446 (ac)MT(ph)PPKS(ph)S(ph)QELLSVR ddPTM_PC-9_AZD4547_30min_R2 1 MTPPKSSQELLSVR 14 1 H3BUW4;H3BMU4;A0A0C4DGM2;C9K0J8;Q8IWY8-4;Q8IWY8-3;Q8IWY8-2;Q8IWY8 H3BUW4 ZSCAN29 Zinc finger and SCAN domain-containing protein 29 3 MT(1)PPKS(1)S(0.995)QELLS(0.006)VR 43.297 0.0039515 14049000.0 1357.9 1546.0 15649.0 16801.0 11608.0 12529.0 5722.7 23285.0 12764.0 13234.0 True False 1789.6839539253954 2045.7142663222344 15441.484035125048 12927.789022862438 9996.429568665097 11745.559649378378 6232.009213661124 19686.838286069375 13438.67898177754 12770.681688116103 0.14014004871727445 0.16018833734035484 1.209135456683905 1.012302188605369 0.7827639755493541 0.9197284793581799 0.4879934654906001 1.541565185544416 1.0523070976142996 1.0 13.640547916478553 -5.251532656555834 24.331811672454098 0.991490743100095 0.15016396279167013 0.6379323256632639 0.2562386595482925 302.9117652932324 743972.9057091981 0.06718257898725612 0.17297948286845344 5.603602797696453e-06 5.251532656555834 -0.8413267803084249 (ac)MT(ph)PPQQPPPLR ddPTM_PC-9_AZD4547_30min_R2 2 MTPPQQPPPLR 11 0 A0A0A0MSF0;D6RA68;A0A0A0MSC7;Q9H9P5-2;Q9H9P5-1 A0A0A0MSF0 UNKL Putative E3 ubiquitin-protein ligase UNKL 1 MT(1)PPQQPPPLR;MT(1)PPQQPPPLR 88.177 0.009251899999999999 0.0 15717.2 10222.0 20146.2 24237.7 18966.0 18649.7 14985.7 22288.5 13149.8 12731.0 True False 20714.942661931073 13526.061597895134 19879.04822470677 18650.072733732093 16332.89827699019 17483.531310799895 16319.398268852381 18844.324463777415 13844.871582151232 12285.291565014819 1.6861580005900403 1.1009963846860331 1.6181177401859075 1.5180814093857118 1.329467696436433 1.4231270961926743 1.3283688207551871 1.5338931407571104 1.1269469274606128 1.0 13.584644476924696 -8.419196239448652 4.228726381109581 1.0041055922308777 1.430316356854927 0.4846082847440216 0.1580575247069083 0.1712435455256547 4.886967757383293 0.14175582113232998 0.037168408110370574 3.808936746381755e-09 8.419196239448652 0.4262107646240494 (ac)MT(ph)PPQQPPPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MTPPQQPPPLR 11 0 A0A0A0MSF0;D6RA68;A0A0A0MSC7;Q9H9P5-2;Q9H9P5-1 A0A0A0MSF0 UNKL Putative E3 ubiquitin-protein ligase UNKL 1 MT(1)PPQQPPPLR 53.013000000000005 0.018992 0.0 10039.0 11903.0 12131.0 11234.0 14850.0 10239.0 9965.3 8172.4 8530.1 10166.0 True False 11738.40442071195 13084.651175813502 12420.249047073694 10604.595401119412 11940.249101616953 9702.048815270657 9021.314641475845 7957.883159373554 8654.836575136258 12009.015325988274 0.9774660204912301 1.0895690296520384 1.0342437502095183 0.883052865972316 0.9942737832782588 0.8078971132857833 0.7512118518121254 0.6626590893053644 0.720694939609798 1.0 13.551830242287242 -6.75508046813012 1.664215882569641 0.7522506854190059 1.0111266496038187 0.5151374444337807 0.09788505824323562 0.2623225404065243 1.50539818636796 0.04095594572703277 0.037486356776287984 1.7575979277528618e-07 6.75508046813012 0.25887596418481285 (ac)MT(ph)T(ph)SLQDGQS(ph)AASR ddPTM_PC-9_Lapatinib_30min_R1 1 MTTSLQDGQSAASR 14 0 Q14449 Q14449 GRB14 Growth factor receptor-bound protein 14 3 MT(0.976)T(0.512)S(0.512)LQDGQS(0.985)AAS(0.015)R 57.174 0.044821 0.0 782.71 927.91 1078.0 844.35 981.94 708.07 657.63 2378.0 1281.2 676.69 True False 771.5484118685653 925.7614814056204 989.3710012003369 906.4463156690304 924.184219768318 677.7874966917877 691.6788635916972 2488.4905613158085 1136.8977643658895 793.6549648672524 0.972145889615414 1.1664533360040963 1.246600909711212 1.1421163550846603 1.1644659967860191 0.8540077573951235 0.8715107876977601 3.135481628004477 1.432483654349782 1.0 9.632368133336527 (ac)MT(ph)TS(ph)QKHR ddPTM_PC-9_AZD4547_30min_R2 1 MTTSQKHR 8 1 E9PJJ8;O75531 E9PJJ8 BANF1 Barrier-to-autointegration factor;Barrier-to-autointegration factor, N-terminally processed 2 MT(0.946)T(0.473)S(0.581)QKHR 45.137 0.026793 3582600.0 20992.0 19412.0 25858.0 26749.0 24748.0 24636.0 22188.0 27958.0 21809.0 24509.0 True False 27667.01933927527 25686.549377650183 25515.106024682947 20582.43131793034 21312.16738157511 23095.50702546777 24162.689016148503 23637.73351092668 22961.779216044055 23650.947369959013 1.1698059661837223 1.0860685187721806 1.078819618747778 0.8702582182426127 0.9011126297902731 0.9765150910953888 1.0216372578309272 0.9994412968400108 0.9708608647622156 1.0 14.529610353328394 -5.5901613512226405 6.836936074412033 0.9633752677789494 1.1170634887937514 0.6788685094038847 0.04754069747522109 0.13186803350805287 10.731854220789279 0.014381920357368926 0.02513998936340726 2.5694409940562148e-06 5.5901613512226405 0.15368822101480195 (ac)MTS(ph)GSKCPS(ph)T(ph)DSGK ddPTM_PC-9_AZD4547_30min_R2 1 MTSGSKCPSTDSGK 14 1 A0A0U1RQP8;A0A0U1RRK7 A0A0U1RQP8 3 MT(0.461)S(0.499)GS(0.251)KCPS(0.826)T(0.818)DS(0.145)GK 48.848 0.043388 0.0 12425.0 7177.6 5049.1 2958.2 4224.9 5172.4 4456.7 3524.7 3874.7 3353.9 True False 16375.891543945078 9497.618834381927 4982.145634976666 2276.232693734402 3638.345562082457 4848.969010331606 4853.337666228099 2980.038604548364 4079.508731643171 3236.480981847708 5.059783028478072 2.93455110277204 1.53937120685083 0.7033048259826017 1.124167137853943 1.498222618185548 1.4995724348293025 0.9207650597245467 1.2604766579886337 1.0 11.660210311021448 -4.870774964955992 1.709996634868821 1.1615960973300372 5.9883742172761085 0.9618078786442861 0.24334625362349552 0.14311640843739584 0.48470182158316055 0.07472795149628211 1.0824141601822928 1.3465579089109881e-05 4.870774964955992 4.826778119946072 up (ac)MVS(ph)RS(ph)GLS(ph)AGPTK ddPTM_PC-9_AZD4547_30min_R2 1 MVSRSGLSAGPTK 13 1 E9PQ29 E9PQ29 LBHD1 3 MVS(1)RS(0.999)GLS(0.999)AGPT(0.003)K 52.49 0.030888 37083000.0 97288.0 55936.0 86160.0 160060.0 130200.0 92711.0 66415.0 69779.0 43349.0 65715.0 True False 128223.56028388963 74016.2181119021 85017.46210405615 123160.63990234869 112123.97741559244 86913.76651396899 72325.8063370968 58996.25891190183 45640.33964126251 63414.33785208935 2.0219963596082073 1.1671842775452623 1.3406662433715693 1.942157626712345 1.7681171358615426 1.370569644938828 1.1405276596247522 0.9303299681139545 0.7197164109434719 1.0 15.952521447193236 -7.332949792912799 1.823435367556283 0.867062325658415 1.616143536498136 0.6379733369499878 0.2516868190658438 0.2492611808710994 1.6143392190843253 0.14554742280597607 0.08551986890363941 4.645689791219089e-08 7.332949792912799 0.749081210839721 (ac)MWLCPLALNLILMAASGAACEVK ddPTM_PC-9_AZD4547_30min_R2 1 MWLCPLALNLILMAASGAACEVK 23 0 Q8IWL1 Q8IWL1 SFTPA2 Pulmonary surfactant-associated protein A2 0 44.729 0.0023772 11698000.0 10832.0 8128.1 12364.0 22894.0 17610.0 15174.0 13489.0 12469.0 7366.3 11939.0 False True 14276.350680403471 10755.34937134136 12200.04528150591 17616.14200877404 15165.155470726417 14225.1673812489 14689.494868344475 10542.202559115265 7755.6675794004905 11521.019243948784 1.2391569164248968 0.9335414813225333 1.058938017824575 1.5290437100889849 1.3163032844243927 1.2347143147704076 1.2750169544296073 0.91504079074014 0.6731754730358619 1.0 13.491980734623429 -7.853465554283143 4.682280476749709 0.8254955107319863 1.2241432900228681 0.507793996427018 0.1647926373584952 0.18190185915922394 6.844764076090799 0.10181330171241017 0.04729016866066517 1.4013107243633419e-08 7.853465554283143 0.3986477792908818 (ac)NKSRWQSR ddPTM_PC-9_Lapatinib_30min_R1 1 NKSRWQSR 8 2 D6RCB5;Q86SY2;Q8WV16-2;Q8WV16-3;Q8WV16-5;Q8WV16 D6RCB5 DCAF4 DDB1- and CUL4-associated factor 4 0 53.553999999999995 0.03488 0.0 11060.0 12563.0 16769.0 11955.0 12760.0 13905.0 9571.3 10799.0 14477.0 11996.0 False True 10902.282371844403 12533.911145368416 15390.317550211923 12834.210580710902 12009.481887125212 13310.315564138158 10066.855081269421 11300.760963687715 12846.447810431617 14069.492616334752 0.7748880978967784 0.8908573668688295 1.0938786472188546 0.9122013800135421 0.8535831543194488 0.9460409075935556 0.7155094611998838 0.8032102700396939 0.9130711505201564 1.0 13.780282681606733 (ac)NLILRYT(ph)FSK ddPTM_PC-9_Lapatinib_30min_R1 1 NLILRYTFSK 10 1 Q5T3N1 Q5T3N1 ANXA1 Annexin 1 NLILRY(0.257)T(0.372)FS(0.372)K 63.565 0.031775 9045800.0 18239.0 67629.0 66387.0 77302.0 75313.0 62826.0 59154.0 65056.0 64766.0 70553.0 True False 17978.908515377043 67472.40920561325 60928.9171212307 82987.04695191245 70883.23741105504 60139.07843455908 62216.70467725507 68078.73925860423 57471.371063784885 82747.99204403683 0.21727304882285273 0.8153963321515497 0.736318980269703 1.002888951163291 0.8566158000949727 0.7267738702656888 0.7518817452892945 0.8227237613496903 0.6945349324392037 1.0 16.336436683574952 -4.76143028608989 11.75115421328564 0.8162653435161268 0.21633076301033854 0.7609360499687293 0.1017940843575569 0.029512907582378622 194.18255117692524 0.025042104179059152 0.14031282152567567 1.732087046876647e-05 4.76143028608989 -0.5999345805057883 (ac)PEGAQGLSLS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PEGAQGLSLSK 11 0 M0R391;C9J7S4;C9JVL3;E7ESZ3;Q9H7P9-2;Q9H7P9-3;Q9H7P9 M0R391 PLEKHG2 Pleckstrin homology domain-containing family G member 2 1 PEGAQGLSLS(1)K 103.74 0.012029999999999999 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)PGPPES(ph)LDMVR ddPTM_PC-9_Lapatinib_30min_R1 1 PGPPESLDMVR 11 0 M0R1U0 M0R1U0 ZNF493 1 PGPPES(1)LDMVR 52.693000000000005 0.018793 0.0 2604.0 1986.9 16704.0 770.13 4006.1 5820.5 3948.2 2504.6 15879.0 1222.6 True False 2566.8664824848834 1982.299455124772 15330.661599304667 826.767929278368 3770.4690742956395 5571.570783248196 4152.618477309033 2620.9728594918297 14090.53980671711 1433.9247809879018 1.7900984183538846 1.3824291771839439 10.691398741810302 0.5765769168929256 2.6294747983209947 3.885539086234122 2.8959806904571996 1.8278314833823512 9.826554358736614 1.0 10.485753631615477 (ac)S(ph)AADEVDGLGVARPHYGSVLDNER ddPTM_PC-9_AZD4547_30min_R2 1 SAADEVDGLGVARPHYGSVLDNER 24 1 P46940;H0YLE8;A0A0J9YXZ5 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 1 S(1)AADEVDGLGVARPHYGSVLDNER 63.184 6.4624e-06 3558400.0 649.1 0.0 1250.4 1118.9 959.7 2283.3 349.87 2114.4 703.22 519.4 True False 855.5002978812682 0.0 1233.8188790031536 860.9548918326757 826.4622206278341 2140.5248900491374 381.00775221200115 1787.6680640783793 740.3907735479164 501.2159640930557 1.706849659965013 0.0 2.461651199070912 1.7177323818696864 1.6489143998501876 4.270663832350974 0.7601668332760113 3.566662261672258 1.4771891292162744 1.0 8.96928855605281 -5.278229147073211 24.465013250590836 2.2026100487570592 0.8534247308578632 0.16792783253099453 1.1070722770103048 820.4225118200993 1195468.918153146 0.2703056175265706 0.5652720107902083 5.2695175217224535e-06 5.278229147073211 -1.3491853178991962 (ac)S(ph)AADEVDGLGVARPHYGSVLDNER ddPTM_PC-9_Lapatinib_30min_R1 1 SAADEVDGLGVARPHYGSVLDNER 24 1 P46940;H0YLE8;A0A0J9YXZ5 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 1 S(1)AADEVDGLGVARPHYGSVLDNER 64.203 3.6424e-05 2751900.0 0.0 0.0 860.93 574.56 706.68 685.47 0.0 744.38 468.55 553.89 True False 0.0 0.0 790.1476586859054 616.8150590759732 665.1144717863358 656.1540460086145 0.0 778.9666122927924 415.77696494976396 649.6291484879673 0.0 0.0 1.2163057346256698 0.9494879663445368 1.0238371743854338 1.0100440344092227 0.0 1.199094304967476 0.6400220278254112 1.0 9.343472556650635 -5.2461978459934 24.249533854687318 0.8678156043231325 3.1939169699363446e-07 0.5282955285342978 0.332400308205793 424.3974572086483 675218.9661638072 0.08447076742963386 0.22146253873009772 5.672861152403081e-06 5.2461978459934 -0.8678152849314356 (ac)S(ph)ASSLLEQRPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASSLLEQRPK 11 1 Q9Y5A9;S4R3J8;S4R3V3 Q9Y5A9 YTHDF2 YTH domain-containing family protein 2 1 S(0.468)AS(0.468)S(0.065)LLEQRPK 65.305 0.0089951 2324800.0 5981.7 6792.8 6016.8 7611.5 9260.0 9873.9 9246.5 10405.0 7597.1 5492.9 True False 6994.283666039704 7467.144291948742 6160.26333084107 7185.052331815946 7445.5694734662 9356.095301992473 8370.604581137186 10131.879775008787 7708.193215198848 6488.7192882275285 1.077914354952821 1.150788616406379 0.9493804643418038 1.1073144040691933 1.1474636430912775 1.441901689131046 1.2900241494995721 1.56146064037491 1.1879375378718893 1.0 12.663718038872071 -6.591281816171257 5.236450622534742 1.3303058116072917 1.0745416177935472 0.33001643682882187 0.14827989955121373 0.19909235212760973 10.312883071763649 0.04689810291972746 0.04708942513808017 2.562820467978588e-07 6.591281816171257 -0.2557641938137445 (ac)S(ph)ASSLLEQRPK ddPTM_PC-9_Lapatinib_30min_R1 1 SASSLLEQRPK 11 1 Q9Y5A9;S4R3J8;S4R3V3 Q9Y5A9 YTHDF2 YTH domain-containing family protein 2 1 S(0.631)AS(0.303)S(0.066)LLEQRPK 58.246 0.0022503 7400100.0 22630.0 22948.0 20532.0 23182.0 21777.0 21639.0 15506.0 18993.0 25706.0 12658.0 True False 22307.292050166252 22894.865315920924 18843.93821581198 24886.881612885012 20496.119675229293 20713.55041297272 16308.824808559302 19875.48411735539 22810.71958381952 14845.918434275196 1.5025875393916195 1.5421656408311455 1.2693009394626904 1.6763450320074478 1.3805895381931585 1.3952353641624997 1.0985392975692667 1.338784407670481 1.5364977037160434 1.0 13.857778727140609 -6.818358782449046 2.5578464700384034 1.2720581150963761 1.484103014928068 0.2917748171015748 0.16642570402496398 0.40253745266674507 5.381159812286686 0.06284007566706427 0.056228480405460086 1.5192918829161145e-07 6.818358782449046 0.21204489983169195 (ac)S(ph)DAAVDTSSEITTK ddPTM_PC-9_AZD4547_30min_R2 4 SDAAVDTSSEITTK 14 0 B8ZZQ6;P06454-2;P06454 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 1 S(0.999)DAAVDT(0.001)SSEITTK;S(1)DAAVDTSSEITTK;S(1)DAAVDTSSEITTK;S(1)DAAVDTSSEITTK 125.23 8.8387e-05 197255000.0 206864.0 181609.0 260074.0 356156.0 319793.0 274239.0 228725.0 297084.0 245038.0 264846.0 True False 272642.44896150153 240310.5576924413 256625.24883066717 274049.7367553474 275395.2619789907 257090.7919774819 249081.08190096266 251176.4941111716 257990.20842500828 255573.82215284856 1.0667855051228403 0.9402784513224562 1.0041139842451854 1.0722918898612752 1.0775566122507167 1.0059355446182046 0.9745954409681175 0.9827942940140125 1.0094547487368037 1.0 17.9633805463071 -10.457606096277782 8.558458291941461 1.0000053928537247 1.0134995773657316 0.009810912216265733 0.042870239088107366 0.0 0.0 0.0442542080054281 0.010733221999084398 3.4865339920160485e-11 10.457606096277782 0.013494184512006901 (ac)S(ph)DAAVDTSSEITTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SDAAVDTSSEITTK 14 0 B8ZZQ6;P06454-2;P06454 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 1 S(0.997)DAAVDT(0.002)SSEITTK;S(1)DAAVDTSSEITTK;S(1)DAAVDTSSEITTK;S(1)DAAVDTSSEITTK;S(1)DAAVDTSSEITTK;S(0.999)DAAVDT(0.001)SSEITTK 132.25 1.1879000000000001e-07 116002000.0 129668.5 150518.7 176081.8 196670.8 186168.4 152786.80000000002 172785.3 162139.2 155201.19999999998 123990.2 True False 151618.8159803848 165461.20179256675 180280.25790594547 185651.9726913367 149690.03844104178 144774.3912422104 156417.82552675766 157883.21780068305 157470.7239381767 146468.64175411715 1.0351622993467329 1.1296698037954989 1.2308454270272353 1.2675202723802013 1.0219937636366732 0.9884326741095137 1.0679270569692494 1.0779318761331043 1.075115615549499 1.0 17.16023229793514 -6.287651913012669 24.815280036043607 1.0414247161582626 1.1678649155982816 0.48588715267110383 0.06406133303887081 650.7099920281196 616022.0882982453 0.0216031865352417 0.024503222706746153 5.156417658292407e-07 6.287651913012669 0.12644019944001905 (ac)S(ph)DAAVDTSSEITTK ddPTM_PC-9_Lapatinib_30min_R1 4 SDAAVDTSSEITTK 14 0 B8ZZQ6;P06454-2;P06454 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 1 S(0.999)DAAVDT(0.001)SSEITTK;S(1)DAAVDTSSEITTK;S(1)DAAVDTSSEITTK;S(1)DAAVDTSSEITTK 133.89 1.7627e-10 206946000.0 441290.0 401143.0 423160.0 359301.0 387071.0 387450.0 345825.0 348116.0 395197.0 316050.0 True False 434997.1236773244 400214.17802965303 388369.4182448375 385725.1941329996 364304.2447908653 370879.66669006343 363730.1263652795 364290.74021993903 350685.7522510976 370678.82138984726 1.1735149098789024 1.0796791047545258 1.0477248653933342 1.040591401167017 0.9828029651786397 1.0005418310640546 0.981254135322558 0.9827665331783555 0.9460636324897485 1.0 18.499810164051183 -1.5228787452814758 0.42928725966576325 0.972752858743759 4.930735300668162 0.9258795930381595 0.016939901464193552 18.703416412216974 0.23539996017408701 0.010809255311777418 63.99444353886685 0.02999999999992137 1.5228787452814758 3.9579824419244027 (ac)S(ph)DCYTELEK ddPTM_PC-9_AZD4547_30min_R2 1 SDCYTELEK 9 0 Q96FQ6 Q96FQ6 S100A16 Protein S100-A16 1 S(0.999)DCY(0.001)TELEK 81.548 0.011909999999999999 0.0 30696.0 28882.0 41340.0 45685.0 57904.0 34294.0 50589.0 57412.0 36897.0 44357.0 True False 40456.689483536284 38217.541681706796 40791.80458892383 35153.02907621397 49865.029095794634 32149.59075870236 55091.32299612121 48540.294596513435 38847.30009328155 42804.074931220035 0.9451597668807079 0.8928482099687206 0.9529888136695014 0.8212542645227074 1.1649598589835322 0.7510871525751254 1.2870579047589514 1.1340110649397441 0.9075607907822689 1.0 15.385460526718408 -7.257900250924349 24.99777702827023 1.0933250232233802 0.9280429779505829 0.25041589406725107 0.13542764945358796 427.44133327978636 3019144.557470387 0.051373393753582325 0.03814415706199529 5.522042553956378e-08 7.257900250924349 -0.16528204527279733 (ac)S(ph)DEFSLADALPEHSPAK ddPTM_PC-9_AZD4547_30min_R2 7 SDEFSLADALPEHSPAK 17 0 Q8NDC0 Q8NDC0 MAPK1IP1L MAPK-interacting and spindle-stabilizing protein-like 1 S(0.976)DEFS(0.021)LADALPEHS(0.003)PAK;S(0.628)DEFS(0.372)LADALPEHSPAK;S(0.995)DEFS(0.004)LADALPEHS(0.001)PAK;S(0.995)DEFS(0.002)LADALPEHS(0.002)PAK;S(0.5)DEFS(0.5)LADALPEHSPAK;S(0.977)DEFS(0.023)LADALPEHSPAK;S(0.996)DEFS(0.003)LADALPEHSPAK 135.99 1.5503999999999996e-82 134361790.0 456245.8 396980.39999999997 513195.50000000006 662363.7000000001 630439.9 524085.8 480094.89999999997 518014.0 518905.79999999993 569377.0 True False 601322.4738978223 525296.5509251663 506390.192354017 509665.98238215275 542914.2020698014 491314.6320769573 522822.416032941 437966.8390775151 546334.1012208133 549443.2845348697 1.094421373093805 0.9560523637482534 0.9216423361743347 0.9276043528561999 0.9881169127936553 0.8942044536823831 0.9515493787052752 0.7971101866287713 0.9943412115470872 1.0 19.067611043248853 -4.753805030813256 3.082270753536798 0.9281621760873979 1.126827756617432 0.4121290386348686 0.05662740410671402 0.37552609711081675 4.981077866687494 0.013754045156440431 0.19089858222957562 1.76276723343777e-05 4.753805030813256 0.19866558053003414 (ac)S(ph)DEFSLADALPEHSPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SDEFSLADALPEHSPAK 17 0 Q8NDC0 Q8NDC0 MAPK1IP1L MAPK-interacting and spindle-stabilizing protein-like 1 S(0.418)DEFS(0.353)LADALPEHS(0.229)PAK;S(0.998)DEFS(0.002)LADALPEHSPAK;S(0.956)DEFS(0.044)LADALPEHSPAK;S(0.943)DEFS(0.056)LADALPEHS(0.001)PAK;S(0.958)DEFS(0.006)LADALPEHS(0.036)PAK;S(0.586)DEFS(0.414)LADALPEHSPAK 163.46 1.0275999999999996e-196 75013600.0 331050.0 326255.0 290386.8 427397.0 416100.0 376056.0 383612.0 406717.0 368364.0 301632.39999999997 True False 387090.2264644576 358643.44025581976 297310.7226100723 403451.3317297704 334568.1919988422 356334.961351247 347273.4942496294 396041.10970228264 373750.6266237793 356315.96639923524 1.0863678952594036 1.0065320504161093 0.8344019091104934 1.132285302303075 0.9389649175136157 1.0000533092923218 0.9746223211915399 1.1114885299822272 1.0489303367478329 1.0 18.44279760603854 -7.742956386811978 24.98149247741207 1.0601571015831102 0.9935354021982071 0.09611017030385205 0.07944794323375977 478.82766006736597 647182.2532455205 0.03645759216063476 0.020999872768591683 1.8073556171094012e-08 7.742956386811978 -0.06662169938490303 (ac)S(ph)DEFSLADALPEHSPAK ddPTM_PC-9_Lapatinib_30min_R1 10 SDEFSLADALPEHSPAK 17 0 Q8NDC0 Q8NDC0 MAPK1IP1L MAPK-interacting and spindle-stabilizing protein-like 1 S(0.886)DEFS(0.007)LADALPEHS(0.107)PAK;S(0.984)DEFS(0.016)LADALPEHSPAK;S(0.5)DEFS(0.5)LADALPEHSPAK;S(0.686)DEFS(0.054)LADALPEHS(0.26)PAK;S(0.952)DEFS(0.024)LADALPEHS(0.024)PAK;S(0.517)DEFS(0.465)LADALPEHS(0.018)PAK;S(0.994)DEFS(0.006)LADALPEHSPAK;S(0.986)DEFS(0.014)LADALPEHSPAK;S(0.563)DEFS(0.41)LADALPEHS(0.027)PAK;S(0.534)DEFS(0.465)LADALPEHS(0.001)PAK 147.58 2.0433999999999996e-113 145506800.0 658435.7999999999 614821.6 615789.6 651807.8 644510.9999999999 591514.1 527459.1000000001 525845.7000000001 594153.6 547670.4 True False 649046.3847496632 613398.0183597271 565161.7561045958 699743.9199790803 606602.1301373796 566216.4208297147 554768.3513208028 550278.4109161085 527233.7648532189 642334.4989150633 1.0104492065208028 0.9549510720594776 0.8798558337738105 1.089376206884395 0.9443710888360541 0.8814977582335746 0.8636751603064068 0.8566851256558033 0.8208087308773613 1.0 19.292965258156926 -6.682844768658203 4.014716943751347 0.873742398547728 0.978421781452405 0.32985053141781295 0.06557467062626142 0.24685916486523699 7.652310928817315 0.022163066545837967 0.021718422311664237 2.0756552933531886e-07 6.682844768658203 0.10467938290467704 (ac)S(ph)DKPDMAEIEKFDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDKPDMAEIEKFDK 14 2 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 1 S(1)DKPDMAEIEKFDK 53.568999999999996 0.019319 0.0 28938.0 18782.0 12459.0 25056.0 29398.0 32188.0 29140.0 33159.0 21386.0 28228.0 True False 33836.631848447265 20646.552834086284 12756.069811020618 23652.193552648027 23637.672935308787 30500.004616264443 26379.64824466961 32288.611384864624 21698.729791662954 33345.51294727496 1.0147281855267558 0.6191703473487442 0.382542317798205 0.7093066341503352 0.7088711747419825 0.9146659301504895 0.7911003884204872 0.9683045342837736 0.6507241266905208 1.0 15.025205021491947 -6.619033132479016 4.310420105678996 0.8579493170795254 0.6607899753320471 0.2104448704759837 0.17037771196143223 0.34338259509060387 11.557080688151595 0.058336444871068795 0.05835134998159641 2.4041793773187e-07 6.619033132479016 -0.1971593417474783 (ac)S(ph)DNDDIEVESDADKR ddPTM_PC-9_AZD4547_30min_R2 1 SDNDDIEVESDADKR 15 1 A0A494C130;Q6V3B1;G3V563;G3V2R5;P61244-2 A0A494C130 MAX 1 S(1)DNDDIEVESDADKR 104.07 8.762e-05 21377000.0 39577.0 41642.0 39615.0 59049.0 53283.0 44327.0 43006.0 49493.0 44017.0 45290.0 True False 52161.662747260714 55101.962146306876 39089.67921601883 45436.16534795575 45885.57518152848 41555.22568265588 46833.45068633866 41844.994085996615 46343.64875751347 43704.4108852031 1.1935102588219755 1.260787207292219 0.8944103907199291 1.039624249078689 1.0499071890490543 0.9508245241380233 1.071595514909342 0.9574547108279173 1.0603883639855658 1.0 15.415491271199238 -5.248867783591978 24.99991729411746 1.0050721783898675 1.2271487630491107 0.7252490446026094 0.05516734334499515 362.9594473849608 721779.3655130103 0.013133049246392121 0.034240464041046165 5.638092755316611e-06 5.248867783591978 0.22207658465924318 (ac)S(ph)DNDDIEVESDADKR ddPTM_PC-9_Lapatinib_30min_R1 2 SDNDDIEVESDADKR 15 1 A0A494C130;Q6V3B1;G3V563;G3V2R5;P61244-2 A0A494C130 MAX 1 S(1)DNDDIEVESDADKR;S(1)DNDDIEVESDADKR 131.83 3.8675e-05 36371700.0 64285.0 59167.0 62822.0 61382.0 63111.0 64078.0 58905.0 54906.0 66554.0 63270.0 True False 63368.28411157478 59030.00244670963 57657.01765993279 65896.23704434934 59398.93506099996 61337.53331311364 61954.812675621404 57457.133204207574 59057.987675310105 74206.13519802432 0.8539493930316143 0.7954868191044298 0.7769845108638385 0.8880160227789868 0.8004585456780589 0.8265830466635959 0.8349014877313123 0.7742908729969449 0.7958639473368299 1.0 16.179250850140203 -10.639314258600828 5.000075500624066 1.00000703819239 0.8157742718930547 0.7266394048370037 0.03380381875131911 2.631681601123941e-06 4.6508697069791323e-07 0.03247735398997052 0.007876614454620718 2.294487739483259e-11 10.639314258600828 -0.18423276629933527 (ac)S(ph)DNGELEDKPPAPPVR ddPTM_PC-9_AZD4547_30min_R2 4 SDNGELEDKPPAPPVR 16 1 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 S(1)DNGELEDKPPAPPVR;S(1)DNGELEDKPPAPPVR;S(1)DNGELEDKPPAPPVR;S(1)DNGELEDKPPAPPVR 76.165 0.00015824 129778000.0 43614.5 43618.2 49915.0 66935.0 57972.0 50607.0 47372.9 54149.0 48463.0 57249.0 True False 57483.00376204371 57716.93014960961 49253.09448611836 51504.169885441166 49923.588469560025 47442.53628989475 51588.99632653243 45781.5162702328 51024.65524082461 55244.72993523945 1.0405156080847544 1.0447499737489565 0.8915437643347198 0.9322910971927432 0.9036805597218572 0.858770354122632 0.9338265638551868 0.8287037754352337 0.9236112711680949 1.0 15.75354922488733 -5.259184917779431 24.81200467559024 0.9026626588088251 1.0426328083958987 0.5939724842799132 0.04392324954270004 101.61655551839388 1118343.6743899882 0.010599125278532134 0.02538475723664746 5.505732185125169e-06 5.259184917779431 0.13997014958707354 (ac)S(ph)DNGELEDKPPAPPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SDNGELEDKPPAPPVR 16 1 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 S(1)DNGELEDKPPAPPVR;S(1)DNGELEDKPPAPPVR;S(1)DNGELEDKPPAPPVR 66.663 1.1414000000000001e-05 97714000.0 66159.0 72497.0 77448.0 84415.0 85348.0 72930.0 76033.0 83058.0 77000.0 69890.0 True False 77358.41200018751 79694.02304401841 79294.65404317543 79685.50122712243 68624.67207574422 69105.42241407245 68830.60380874967 80877.81550722518 78125.97933031176 82560.50375106437 0.9369905522068741 0.9652802420429877 0.9604429532341989 0.9651770229913976 0.8312046191319359 0.8370276254907365 0.8336989320739495 0.9796187260567981 0.9462875803892434 1.0 16.333164153083693 -6.197487633519427 24.99958838213291 0.8966925479377994 0.9578140408449043 0.16053053320381738 0.056900010835250155 366.84806579658147 143405.0087677417 0.017856180074605887 0.023052227161986336 6.346179713906689e-07 6.197487633519427 0.06112149290710489 (ac)S(ph)DNGELEDKPPAPPVR ddPTM_PC-9_Lapatinib_30min_R1 3 SDNGELEDKPPAPPVR 16 1 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 S(1)DNGELEDKPPAPPVR;S(1)DNGELEDKPPAPPVR;S(1)DNGELEDKPPAPPVR 60.08 0.0039508 61334300.0 79067.0 69922.3 73339.0 60516.3 67989.1 67165.9 59067.4 65104.9 62684.6 48682.1 True False 77939.49008088795 69760.39921036341 67309.3505167267 64966.870578458846 63990.1148097135 64293.37102836014 62125.620952992096 68129.9113311225 55624.40024989856 57096.73612017921 1.3650428269111248 1.2217931172725753 1.1788651171767792 1.137838605024888 1.120731571679069 1.12604284232698 1.0880765727523884 1.1932365308538875 0.9742133093705807 1.0 15.801120657224862 -1.5228787452803376 0.33067531937158806 1.0586552865449848 4.004226397492887 0.7383146023301285 0.05414424402520991 30.963559690523496 0.4406732410364789 0.04754962678759184 55.77811693813893 0.029999999999999995 1.5228787452803376 2.9455711109479017 (ac)S(ph)DQDHSMDEMTAVVK ddPTM_PC-9_AZD4547_30min_R2 4 SDQDHSMDEMTAVVK 15 0 P08047;H3BUU5;P08047-3 P08047 SP1 Transcription factor Sp1 1 S(0.844)DQDHS(0.154)MDEMT(0.002)AVVK;S(0.969)DQDHS(0.031)MDEMTAVVK;S(0.917)DQDHS(0.053)MDEMT(0.03)AVVK;S(0.97)DQDHS(0.03)MDEMTAVVK 74.962 0.0006414 39250000.0 84774.7 80001.9 109073.4 178508.0 140286.0 132699.7 102641.8 141641.5 108998.5 122178.4 True False 111731.29117669864 105860.94965257739 107627.01544870641 137355.73852110756 120809.71041262515 124401.96678143625 111776.72135648581 119754.06077287067 114759.93818515203 117900.97140421082 0.9476706582309649 0.897880215843553 0.9128594460830924 1.1650093878378505 1.0246710351388202 1.0551394555939446 0.9480559831290221 1.0157173375807629 0.9733587163731663 1.0 16.84721607938947 (ac)S(ph)DQDHSMDEMTAVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SDQDHSMDEMTAVVK 15 0 P08047;H3BUU5;P08047-3 P08047 SP1 Transcription factor Sp1 1 S(0.93)DQDHS(0.07)MDEMTAVVK;S(0.5)DQDHS(0.5)MDEMT(0.001)AVVK 76.655 0.019922 15406100.0 47102.0 48332.0 57693.0 69566.0 80861.0 68072.0 69046.0 67965.0 59976.0 47194.0 True False 55075.4382930943 53130.08154493976 59068.61992192093 65668.44255601492 65016.86751554537 64502.18448609272 62505.4630302491 66180.99076487015 60853.035536555566 55749.89861250153 0.9879020350495133 0.9530076801435781 1.0595287416123695 1.1779114256772698 1.1662239597502297 1.1569919603697458 1.121176263740015 1.187105132241972 1.0915362547925727 1.0 15.766681560880611 -5.496817422427962 3.718078327789819 1.1386151666488173 0.9729852918829027 0.5850247416925729 0.05259071563278295 0.13325689179997197 3.919308998620675 0.013434363379544885 0.02815245459242333 3.185536441045599e-06 5.496817422427962 -0.16562987476591462 (ac)S(ph)DQDHSMDEMTAVVK ddPTM_PC-9_Lapatinib_30min_R1 6 SDQDHSMDEMTAVVK 15 0 P08047;H3BUU5;P08047-3 P08047 SP1 Transcription factor Sp1 1 S(0.884)DQDHS(0.115)MDEMT(0.001)AVVK;S(0.874)DQDHS(0.121)MDEMT(0.006)AVVK;S(0.497)DQDHS(0.497)MDEMT(0.006)AVVK;S(0.767)DQDHS(0.233)MDEMT(0.001)AVVK;S(0.997)DQDHS(0.003)MDEMTAVVK;S(0.547)DQDHS(0.453)MDEMTAVVK 89.40299999999999 7.938399999999999e-29 26997100.0 105667.1 91434.1 114715.1 90029.1 93552.9 97587.1 80405.6 89377.1 110160.5 64002.0 True False 104160.267777027 91222.38995914435 105283.66729109183 96650.14034227366 88050.30235407819 93413.52721964101 84568.60854037774 93529.88635314518 97753.06444850801 75064.66042269563 1.387607260067407 1.2152508177012078 1.402573017692085 1.2875584835530904 1.1729927486284395 1.244440815340019 1.1266101526892223 1.2459909340356736 1.3022514709059099 1.0 16.19584624291568 -14.52287874485044 0.09422870008407153 0.22086678752236769 1.4458408835207432 0.5448015279788124 0.07691060815654037 164.90614956594024 1.066414023814996 25.958897293165542 1.6033973560828731 3.0000000029696304e-15 14.52287874485044 1.2249740959983755 (ac)S(ph)DQEAKPSTEDLGDK ddPTM_PC-9_AZD4547_30min_R2 2 SDQEAKPSTEDLGDK 15 1 B8ZZJ0;B9A032;B8ZZN6;P63165 B8ZZJ0 SUMO1 Small ubiquitin-related modifier 1 1 S(0.983)DQEAKPS(0.013)T(0.004)EDLGDK;S(0.997)DQEAKPS(0.001)T(0.001)EDLGDK 75.02 4.0793e-05 12109200.0 52021.0 62980.0 45408.0 42064.0 47963.0 64156.0 61966.0 57549.0 64972.0 50002.0 True False 68562.59589598126 83337.05335897424 44805.86025093989 32366.794682321633 41304.165351644064 60144.31517802847 67480.85395595178 48656.12439446023 68406.28727703307 48251.44519942431 1.4209438828746062 1.7271410838481691 0.9285910518484215 0.6707943057155892 0.8560192379924169 1.246476969331191 1.3985250322980356 1.008386882369292 1.4177044230345504 1.0 15.558284533346088 (ac)S(ph)DQEAKPSTEDLGDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDQEAKPSTEDLGDK 15 1 B8ZZJ0;B9A032;B8ZZN6;P63165 B8ZZJ0 SUMO1 Small ubiquitin-related modifier 1 1 S(0.994)DQEAKPS(0.002)T(0.004)EDLGDK 75.479 0.00010325 4502400.0 29688.0 47362.0 26846.0 31965.0 31529.0 19522.0 31412.0 24663.0 19063.0 20014.0 True False 34713.592035272064 52063.78635544642 27486.110454021946 30174.104681928224 25351.118782820282 18498.23195348313 28436.427956814085 24015.622382608526 19341.760311347174 23642.379769263174 1.4682782517689812 2.202138146140989 1.1625779943589225 1.2762718887189508 1.072274408508512 0.7824183577971362 1.202773503950881 1.0157870153930357 0.818097014772298 1.0 14.529087639621446 -5.395956777850672 5.48990228172991 1.0376840878361981 1.8294084034694336 0.6828412395295425 0.2176740684599297 0.11634000429812215 4.662610167370116 0.05586514809138286 0.1188852523731294 4.018308001358086e-06 5.395956777850672 0.7917243156332354 (ac)S(ph)DQEAKPSTEDLGDK ddPTM_PC-9_Lapatinib_30min_R1 2 SDQEAKPSTEDLGDK 15 1 B8ZZJ0;B9A032;B8ZZN6;P63165 B8ZZJ0 SUMO1 Small ubiquitin-related modifier 1 1 S(1)DQEAKPSTEDLGDK;S(0.961)DQEAKPS(0.029)T(0.01)EDLGDK 75.08800000000001 0.00028674 21555900.0 51226.0 84505.0 64746.0 73196.0 79359.0 68778.0 80569.0 90051.0 65457.0 80121.0 True False 50495.50784630211 84309.33386447176 59422.83380678755 78579.07801469794 74691.25964579696 65836.52526934873 84740.46859285538 94235.09820733816 58084.54336723227 93969.80809547825 0.5373588482270394 0.8971959778699246 0.6323609147569061 0.8362162231390052 0.7948431646248201 0.70061359710829 0.9017839911597417 1.002823141998868 0.6181192081207117 1.0 16.519909682003686 -2.409902549844793 0.07072610849215204 1.185889668156821 6.826785451964161e-12 0.2621768497850614 0.13354229305623647 297.66895142370413 1.8487228024443974 6.175432546169092 36.10646364731752 0.0038913245156897295 2.409902549844793 -1.1858896681499942 (ac)S(ph)DQEAKPSTEDLGDKK ddPTM_PC-9_AZD4547_30min_R2 2 SDQEAKPSTEDLGDKK 16 2 B8ZZJ0;B9A032;B8ZZN6;P63165 B8ZZJ0 SUMO1 Small ubiquitin-related modifier 1 1 S(1)DQEAKPSTEDLGDKK;S(0.996)DQEAKPS(0.003)T(0.001)EDLGDKK 84.169 0.0039591 68696000.0 102670.0 111807.0 97859.0 120045.0 118041.0 102969.0 115183.0 118426.0 106529.0 107777.0 True False 135316.92433133535 147946.42624494826 96561.32572006522 92370.47992676162 101653.04468597469 96530.33215235407 125434.06386096218 100125.98285875228 112159.90545673617 104003.76003476551 1.3010772330356397 1.4225103611205399 0.9284407187565863 0.8881455814278713 0.9773977849646489 0.9281427144565418 1.2060531640301575 0.9627150290074417 1.0784216399411357 1.0 16.666276161317136 -5.260850084382265 24.999992264858296 0.9953715729206777 1.3617938216732106 0.7263935968042438 0.08975793954592722 25.66396983350993 1088693.5289340508 0.02391714801192779 0.05604108234610887 5.4846625921673085e-06 5.260850084382265 0.36642224875253293 (ac)S(ph)DQEAKPSTEDLGDKK ddPTM_PC-9_Lapatinib_30min_R1 2 SDQEAKPSTEDLGDKK 16 2 B8ZZJ0;B9A032;B8ZZN6;P63165 B8ZZJ0 SUMO1 Small ubiquitin-related modifier 1 1 S(1)DQEAKPSTEDLGDKK;S(1)DQEAKPSTEDLGDKK 76.165 0.0084505 113076000.0 65102.0 102095.0 89938.0 88124.0 103056.0 94701.0 103168.0 102093.0 76111.0 86742.0 True False 64173.6335417554 101858.60530019787 82543.6448107198 94604.93293304637 96994.44869589167 90650.85898881333 108509.5342350991 106836.6134888204 67538.57769563863 101735.2391235501 0.630790609965748 1.001212619911356 0.8113574560971593 0.9299131131756176 0.9534007049228922 0.8910467972530581 1.0665874987851762 1.0501436317368364 0.6638661124452453 1.0 16.634459961920292 -4.753210357131248 24.96554972347244 0.9314072833172052 0.6307900451328685 0.3820303437848237 0.11404163140832849 317.8652921130324 964276.5824468862 0.02747037466653572 0.30220505571831285 1.7651826205647528e-05 4.753210357131248 -0.3006172381843367 (ac)S(ph)DQEAKPSTEDLGDKKEGEYIK ddPTM_PC-9_AZD4547_30min_R2 2 SDQEAKPSTEDLGDKKEGEYIK 22 3 B8ZZJ0;B9A032;B8ZZN6;P63165 B8ZZJ0 SUMO1 Small ubiquitin-related modifier 1 1 S(0.735)DQEAKPS(0.133)T(0.133)EDLGDKKEGEYIK;S(0.732)DQEAKPS(0.134)T(0.134)EDLGDKKEGEYIK 56.528999999999996 0.004123699999999999 26094900.0 73223.0 41288.0 73050.0 137467.0 117074.0 92827.0 61136.0 55165.0 65073.0 108869.0 True False 96506.39086698498 54633.53856915418 72081.30926997791 105776.1069939785 100820.29594433986 87022.5130156314 66576.98556387474 46640.51681559014 68512.62593083757 105057.52944714484 0.918605181131144 0.5200344883099568 0.6861127388898147 1.00683984813478 0.9596674933714602 0.8283319955607086 0.633719314686246 0.44395215708032904 0.6521438900322394 1.0 16.680820037749854 -7.263770480840696 22.634082552180054 0.6361164848019305 0.8150650000124808 0.0967797326867561 0.18489367650104416 106.27738690306211 1031883.0070484434 0.07734247431107273 0.05504803800784323 5.4479049168376717e-08 7.263770480840696 0.17894851521055033 (ac)S(ph)DQEAKPSTEDLGDKKEGEYIK ddPTM_PC-9_Lapatinib_30min_R1 2 SDQEAKPSTEDLGDKKEGEYIK 22 3 B8ZZJ0;B9A032;B8ZZN6;P63165 B8ZZJ0 SUMO1 Small ubiquitin-related modifier 1 1 S(0.934)DQEAKPS(0.033)T(0.033)EDLGDKKEGEYIK;S(0.771)DQEAKPS(0.114)T(0.114)EDLGDKKEGEYIK 51.818999999999996 0.00038237 30403000.0 390550.0 123164.0 156998.0 152916.0 117696.0 131426.0 67882.0 71289.0 144887.0 93076.0 True False 384980.6853819022 122878.82132517334 144090.23046980565 164161.95275282208 110773.35267923899 125805.21634896974 71396.59781082316 74601.34719328972 128568.30033225157 109164.06258402565 3.526624754237002 1.1256343746880175 1.3199419942702908 1.5038094851633386 1.0147419403155193 1.1524416861284827 0.6540302377979735 0.6833874209826851 1.1777529828856461 1.0 16.73613846563058 -4.76095966256714 6.5299993187385965 1.0651893984631506 3.5953623234714387 0.9006793775764191 0.24479130916652897 0.03846173095386627 7.802200042586159 0.06863013454814107 0.432379717227621 1.7339650415925072e-05 4.76095966256714 2.530172925008288 (ac)S(ph)DSGEQNYGER ddPTM_PC-9_AZD4547_30min_R2 2 SDSGEQNYGER 11 0 P62995;P62995-2 P62995 TRA2B Transformer-2 protein homolog beta 1 S(0.998)DS(0.002)GEQNYGER;S(1)DSGEQNYGER 170.5 4.7436e-13 18655600.0 0.0 0.0 968.65 0.0 1789.2 0.0 0.0 0.0 0.0 849.75 True False 0.0 0.0 955.8050680953339 0.0 1540.8004638400744 0.0 0.0 0.0 0.0 820.0005111437698 0.0 0.0 1.1656152101199773 0.0 1.8790237846204556 0.0 0.0 0.0 0.0 1.0 9.679480998803436 -5.095556744071027 24.999688884726343 0.47261973093559234 3.242087313161385e-06 0.09410719145746205 0.620741154037911 116.48789377749287 30462.010845612418 0.1594565191466776 0.4218827352017072 8.024967013666192e-06 5.095556744071027 -0.47261648884827917 (ac)S(ph)DSGEQNYGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDSGEQNYGER 11 0 P62995;P62995-2 P62995 TRA2B Transformer-2 protein homolog beta 1 S(0.984)DS(0.016)GEQNYGER 123.21 0.0033759 13157000.0 0.0 0.0 0.0 0.0 1000.7 0.0 0.0 0.0 953.44 0.0 True False 0.0 0.0 0.0 0.0 804.620018585057 0.0 0.0 0.0 967.3822562687326 0.0 0.0 (ac)S(ph)DSGEQNYGER ddPTM_PC-9_Lapatinib_30min_R1 2 SDSGEQNYGER 11 0 P62995;P62995-2 P62995 TRA2B Transformer-2 protein homolog beta 1 S(0.921)DS(0.079)GEQNYGER;S(1)DSGEQNYGER 113.62 0.00093897 6487500.0 574.64 0.0 1225.1799999999998 0.0 0.0 994.77 1755.61 723.99 682.9 0.0 True False 566.44552822393 0.0 1124.4504297315666 0.0 0.0 952.2260060221298 1846.5068955342963 757.6292184554381 605.9846107441971 0.0 0.0 (ac)S(ph)EGESQTVLSSGSDPK ddPTM_PC-9_AZD4547_30min_R2 1 SEGESQTVLSSGSDPK 16 0 F8W6G1;Q9UHY1;C9JDW7;C9JHZ6 F8W6G1 NRBP1 Nuclear receptor-binding protein 1 S(0.837)EGES(0.16)QT(0.003)VLSSGSDPK 59.708999999999996 3.6944000000000004e-05 7001100.0 30596.0 30136.0 37066.0 43899.0 40628.0 37991.0 36891.0 45567.0 32822.0 42100.0 True False 40324.89156366552 39876.87265840026 36574.480621505856 33778.76378278903 34987.50349032783 35615.4167642696 40174.22753266336 38525.66717549167 34556.90391255897 40626.09181424268 0.992586039239158 0.9815581779495767 0.9002707124460243 0.8314549166392343 0.8612077098211529 0.8766636211801095 0.9888774858372937 0.9482986291579578 0.8506086204542083 1.0 15.310118965102886 -10.11619288041206 16.069877525919146 0.9999973136460834 0.9142032056236913 0.1669982760105001 0.05720377162011356 0.0 0.0 0.060508929828734306 0.014675571116291692 7.6525666291365e-11 10.11619288041206 -0.08579410802239207 (ac)S(ph)EGESQTVLSSGSDPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SEGESQTVLSSGSDPK 16 0 F8W6G1;Q9UHY1;C9JDW7;C9JHZ6 F8W6G1 NRBP1 Nuclear receptor-binding protein 1 S(0.771)EGES(0.229)QTVLSSGSDPK;S(0.79)EGES(0.183)QT(0.026)VLS(0.001)SGSDPK;S(0.994)EGES(0.006)QTVLSSGSDPK 84.169 2.1388000000000003e-05 24980900.0 132953.0 130277.0 128861.0 158793.0 167509.0 139804.0 163625.0 157087.0 144152.0 113783.0 True False 155459.31695855348 143210.0395893016 131933.5349480636 149896.3430238519 134686.81392341765 132472.43212912374 148125.25545758603 152963.6326974347 146259.95029120913 134410.9571942679 1.1565970528270535 1.0654640259894597 0.9815683014397137 1.1152092519302763 1.0020523381047801 0.9855776262173155 1.1020325913124513 1.1380294872564005 1.0881549640318056 1.0 17.03629122598715 (ac)S(ph)EGESQTVLSSGSDPK ddPTM_PC-9_Lapatinib_30min_R1 4 SEGESQTVLSSGSDPK 16 0 F8W6G1;Q9UHY1;C9JDW7;C9JHZ6 F8W6G1 NRBP1 Nuclear receptor-binding protein 1 S(0.989)EGES(0.011)QTVLSSGSDPK;S(0.991)EGES(0.009)QTVLSSGSDPK;S(0.895)EGES(0.105)QTVLSSGSDPK;S(0.963)EGES(0.036)QTVLSSGSDPK 115.82 4.1203e-17 79323000.0 292289.0 249484.0 288396.0 264561.0 285678.0 258910.0 240745.0 258649.0 287155.0 229504.0 True False 288120.9052607624 248906.33512625113 264685.19412075396 284017.69848962466 268874.98170455784 247837.02284868824 253209.59812566824 270666.7767845969 254812.5800237957 269173.46060514305 1.0703912065217076 0.9247060782540436 0.9833257466233901 1.055147479439873 0.9988911280483812 0.9207335013322367 0.940693029529785 1.0055477838569102 0.9466482299218433 1.0 18.03817664760637 -6.558493574712659 24.459325063724283 0.961485124157735 1.003923888948236 0.19682778283602398 0.04413565288991209 252.67428081337957 173528.04099696767 0.014662106795540532 0.014662138589227196 2.7637988086379364e-07 6.558493574712659 0.042438764790501016 (ac)S(ph)EKSVEAAAELSAK ddPTM_PC-9_AZD4547_30min_R2 1 SEKSVEAAAELSAK 14 1 P20962;F5H7R9;F5GXR3 P20962 PTMS Parathymosin 1 S(0.844)EKS(0.156)VEAAAELSAK 77.062 0.00076752 11055000.0 22787.0 26528.0 28611.0 45278.0 36007.0 31003.0 30922.0 32368.0 30896.0 31110.0 True False 30032.79200095587 35102.65721668577 28231.5994459047 34839.85663812664 31008.04957606169 29064.377508953443 33673.99809614857 27366.26934264521 32529.099484565897 30020.84836914702 1.0003978445799395 1.1692759906399388 0.9403997881325311 1.1605220548641193 1.032883854405968 0.9681397791150845 1.1216870916531445 0.9115754826825623 1.0835503075921282 1.0 14.873677126683509 -6.50912822520472 24.721353155643882 1.0160635618241074 1.0696792935993822 0.0767062166879825 0.08298692403408427 1434.2580659155649 2578581.764906039 0.0243746515845486 0.026497958503795983 3.096504922878951e-07 6.50912822520472 0.05361573177527479 (ac)S(ph)EKSVEAAAELSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEKSVEAAAELSAK 14 1 P20962;F5H7R9;F5GXR3 P20962 PTMS Parathymosin 1 S(0.766)EKS(0.234)VEAAAELSAK 66.92 0.027089999999999996 5697700.0 6199.1 2705.9 7399.5 5477.0 6078.6 6282.6 5361.7 7367.6 5562.0 4882.0 True False 7248.485192193982 2974.5238693298943 7575.932142760015 5170.141446673581 4887.54196559521 5953.129396114796 4853.8009606535725 7174.20830661747 5643.333727729791 5767.067954109261 1.2568752873857074 0.5157774961209586 1.3136540444892568 0.8964939355343738 0.8474916551161228 1.0322627448620505 0.8416410209272893 1.2439957988540027 0.9785446907572322 1.0 12.493622306619951 -7.747222228325939 24.99985384914593 1.083452769929341 0.9507026547096777 0.053756324264412236 0.22147620540858567 629.6050092850057 1107119.4609833255 0.09749359957847432 0.05594738076008133 1.7896898360643417e-08 7.747222228325939 -0.1327501152196633 (ac)S(ph)EKSVEAAAELSAK ddPTM_PC-9_Lapatinib_30min_R1 1 SEKSVEAAAELSAK 14 1 P20962;F5H7R9;F5GXR3 P20962 PTMS Parathymosin 1 S(0.83)EKS(0.17)VEAAAELSAK 58.172 0.00036039 7002000.0 19124.0 17158.0 17635.0 16460.0 13813.0 16623.0 17113.0 14302.0 17999.0 12454.0 True False 18851.28825308793 17118.271705184383 16185.118373068588 17670.523308950353 13000.546497402867 15912.073040105632 17999.027405447912 14966.523132017937 15971.763082127412 14606.657306088113 1.2905956412923192 1.1719499777713973 1.1080644964760396 1.2097581903003372 0.890042548748247 1.0893712850696795 1.2322482158834414 1.024637110215479 1.093457780752501 1.0 13.834338438615266 -3.933261928899686 0.7507951606646325 1.0738777479112835 1.8825017019389851 0.35625796148734823 0.09141332361704804 10.161198011373106 1.7140908908750578 0.035398651270390144 9.31276961506474 0.00011661061105043274 3.933261928899686 0.8086239540277016 (ac)S(ph)ESGHSQPGLYGIER ddPTM_PC-9_AZD4547_30min_R2 2 SESGHSQPGLYGIER 15 0 Q9H0W8-2;Q9H0W8;M0QZH1;M0QX70;M0QYR7;M0R2N0;M0QZC7 Q9H0W8-2 SMG9 Protein SMG9 1 S(0.899)ES(0.098)GHS(0.004)QPGLYGIER;S(0.999)ESGHSQPGLYGIER 142.89 8.168099999999999e-18 44528000.0 2761.3 3840.1 8941.2 8636.2 8129.3 5378.799999999999 6209.9 7636.9 2227.3 2135.5 True False 3639.3359613919956 5081.33722775162 8822.633845923707 6645.257517959919 7000.687016932218 5042.462785703281 6762.569069829663 6456.792583503678 2345.0305308769284 2060.736794995613 1.7660362886856413 2.4657866254882093 4.281300682041973 3.2246997938298403 3.3971766961860466 2.4469222842764915 3.2816267881721695 3.1332446720918687 1.1379573250556343 1.0 11.008944534903907 -8.265970921013347 16.196136049415372 1.0689048759855087 3.0362668218530904 0.5932644066881682 0.6388469988219996 2.2199632399008644 7907.4493700384 0.5551572207164557 0.16764073917313674 5.420371822841471e-09 8.265970921013347 1.9673619458675817 (ac)S(ph)ESGHSQPGLYGIER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SESGHSQPGLYGIER 15 0 Q9H0W8-2;Q9H0W8;M0QZH1;M0QX70;M0QYR7;M0R2N0;M0QZC7 Q9H0W8-2 SMG9 Protein SMG9 1 S(0.654)ES(0.345)GHS(0.002)QPGLYGIER 88.596 0.00017416 15896000.0 4351.2 0.0 2691.5 0.0 4600.7 0.0 3126.6 0.0 3274.1 0.0 True False 5087.772219882635 0.0 2755.6755675705913 0.0 3699.225861401289 0.0 2830.425813376253 0.0 3321.977518511346 0.0 0.0 (ac)S(ph)ESGHSQPGLYGIER ddPTM_PC-9_Lapatinib_30min_R1 2 SESGHSQPGLYGIER 15 0 Q9H0W8-2;Q9H0W8;M0QZH1;M0QX70;M0QYR7;M0R2N0;M0QZC7 Q9H0W8-2 SMG9 Protein SMG9 1 S(0.757)ES(0.216)GHS(0.026)QPGLYGIER;S(0.997)ES(0.001)GHS(0.002)QPGLYGIER 131.12 1.7619000000000002e-17 12812000.0 4875.299999999999 3715.4 6157.900000000001 4622.4 6417.700000000001 3571.6 4866.2 3931.0 7626.2 4014.3 True False 4805.777327979476 3706.797219573498 5651.621232181402 4962.34671587437 6040.223503683663 3418.850993806249 5118.1480255005345 4113.64861082104 6767.25704855381 4708.166406281478 1.020732258224299 0.7873122782210954 1.2003868904551034 1.0539871125314884 1.2829248124333497 0.7261533894054663 1.087078829387184 0.8737262568571807 1.4373444913767623 1.0 12.200949596812958 -5.258961346917724 24.992490792061595 1.0717384183162493 0.9040222792697015 0.11481846012248198 0.19656934064135878 478.12664621753754 4822127.928615981 0.04849600884024022 0.11664767515735615 5.508567215797207e-06 5.258961346917724 -0.1677161390465478 (ac)S(ph)ESSSKSSQPLASKQEK ddPTM_PC-9_Lapatinib_30min_R1 1 SESSSKSSQPLASKQEK 17 2 P17096;P17096-3;A0A669KAX1;P17096-2 P17096;P17096-2 HMGA1 High mobility group protein HMG-I/HMG-Y 1 S(0.216)ES(0.216)S(0.192)S(0.192)KS(0.153)S(0.03)QPLASKQEK 49.049 0.009407899999999999 6010000.0 57995.0 7657.3 13823.0 10724.0 5442.0 5547.2 1842.5 3616.8 10122.0 4783.5 True False 57167.98066501951 7639.569992313108 12686.526298323057 11512.678734215284 5121.912259383655 5309.959187154783 1937.8956345782613 3784.849731777549 8981.953770614686 5610.321601386904 10.189786740725745 1.3616991208533502 2.261283256059131 2.052053260435067 0.9129445018120687 0.9464625318167376 0.3454161405113037 0.6746225975426992 1.6009695002857403 1.0 12.45386775771141 -4.761228721517673 7.489045366087518 1.2301464232334633 10.336897427464674 0.9574870666127064 0.5658506044266992 0.02083986032262254 8.284217402765618 0.1608906354893123 0.960837547717638 1.7328911289687775e-05 4.761228721517673 9.10675100423121 (ac)S(ph)ETAPAAPAAAPPAEK ddPTM_PC-9_AZD4547_30min_R2 1 SETAPAAPAAAPPAEK 16 0 P16403 P16403 HIST1H1C Histone H1.2 1 S(0.5)ET(0.5)APAAPAAAPPAEK 46.88 0.0013064 9540300.0 46071.0 68632.0 65186.0 70067.0 65577.0 63878.0 66022.0 73601.0 55122.0 68925.0 True False 60720.619663669546 90815.95182809015 64321.59104822426 53914.135674358855 56472.76549141543 59883.69856197556 71897.83009843853 62227.656632724626 58035.63638620668 66511.95672913712 0.9129278801847286 1.3654079100082481 0.9670680913834352 0.8105931373199325 0.8490618569739989 0.9003448628920294 1.0809760174585572 0.9355860163029055 0.8725594500632518 1.0 16.021326094046678 -5.49960099446236 24.470257204361086 0.9188843742535352 1.1459354879111232 0.32272551948151584 0.12437241161331612 591.0746368828226 621353.5373093428 0.03147329034251466 0.06479255187222635 3.1651843194706477e-06 5.49960099446236 0.227051113657588 (ac)S(ph)ETAPAAPAAAPPAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SETAPAAPAAAPPAEK 16 0 P16403 P16403 HIST1H1C Histone H1.2 1 S(0.5)ET(0.5)APAAPAAAPPAEK 53.754 0.00058289 5240400.0 34010.0 46166.0 44840.0 40660.0 70835.0 37423.0 43026.0 39640.0 30826.0 28724.0 True False 39767.221271881004 50749.05537953506 45909.15565664698 38381.9520214986 56955.39024330223 35460.47200057366 38950.26579873559 38599.49200205177 31276.77193293752 33931.4338209411 1.1719876466681551 1.4956354525818714 1.3529978101990408 1.1311621024930227 1.67854357537204 1.045062586735987 1.147910990271713 1.1375732663035811 0.9217639342324158 1.0 15.050334774014948 -6.863632327789682 22.893296844595888 1.0651270273638447 1.3598502664950323 0.5028290309432015 0.15650825740899052 5.5973687519086495 1241.009499381235 0.052871957091519345 0.046628678245377794 1.3688872303832978e-07 6.863632327789682 0.2947232391311876 (ac)S(ph)ETAPAAPAAAPPAEK ddPTM_PC-9_Lapatinib_30min_R1 1 SETAPAAPAAAPPAEK 16 0 P16403 P16403 HIST1H1C Histone H1.2 1 S(0.5)ET(0.5)APAAPAAAPPAEK 53.034 0.0035805999999999998 6346400.0 32890.0 76017.0 79850.0 58067.0 67789.0 71612.0 69200.0 74355.0 64094.0 54131.0 True False 32420.982568712698 75840.98730697064 73285.04122991358 62337.440885833545 63801.784298301834 68549.32169572545 72782.83740179954 77809.80474627274 56875.0587802586 63487.47122497635 0.5106674111152515 1.1945819520550434 1.154322889475598 0.9818857119845344 1.0049507889865652 1.0797299116358212 1.14641260704626 1.2255930697025763 0.8958469707938788 1.0 15.95418429450543 -4.754546864244804 24.99998172357311 1.0825895922412176 0.5106664336024097 0.7415538687578164 0.10004124170493532 119.80529073019895 434509.86374088365 0.02491933103635008 0.24074768342584563 1.7597587599032437e-05 4.754546864244804 -0.5719231586388079 (ac)S(ph)ETAPAAPAAPAPAEKTPVK ddPTM_PC-9_AZD4547_30min_R2 5 SETAPAAPAAPAPAEKTPVK 20 1 P10412 P10412 HIST1H1E Histone H1.4 1 S(0.485)ET(0.485)APAAPAAPAPAEKT(0.03)PVK;S(0.49)ET(0.49)APAAPAAPAPAEKT(0.02)PVK;S(0.353)ET(0.353)APAAPAAPAPAEKT(0.293)PVK;S(0.5)ET(0.5)APAAPAAPAPAEKTPVK;S(0.498)ET(0.498)APAAPAAPAPAEKT(0.003)PVK 126.12 6.4692e-10 1317783400.0 204779.7 310082.0 239318.0 273838.0 247841.0 239250.5 282323.0 255945.7 252055.0 252230.0 True False 269895.38491763425 410309.94251599617 236144.48695239687 210708.87985492585 213432.55519706508 224290.12841356863 307449.2000678783 216395.1731120819 265378.1127195187 243399.5044728375 1.1088575775952478 1.6857468276472407 0.9701929651165323 0.8656914906679286 0.8768816340005465 0.9214896673653606 1.2631463680822264 0.8890534661553956 1.0902984921612031 1.0 17.892966705367222 -5.2901574014518795 24.38562288140403 0.9802329716138258 1.397302192151762 0.48038750574180455 0.17164274381226016 358.2768478803077 304226.65733220393 0.04314212230678949 0.08983611044958485 5.126755411981218e-06 5.2901574014518795 0.41706922053793627 (ac)S(ph)ETAPAAPAAPAPAEKTPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SETAPAAPAAPAPAEKTPVK 20 1 P10412 P10412 HIST1H1E Histone H1.4 1 S(0.492)ET(0.492)APAAPAAPAPAEKT(0.016)PVK;S(0.491)ET(0.491)APAAPAAPAPAEKT(0.018)PVK;S(0.5)ET(0.5)APAAPAAPAPAEKTPVK;S(0.482)ET(0.482)APAAPAAPAPAEKT(0.036)PVK;S(0.437)ET(0.437)APAAPAAPAPAEKT(0.126)PVK 124.12 2.4749000000000002e-09 947588000.0 188384.0 234504.0 214317.0 264273.0 439544.0 222837.0 306254.0 337854.0 238134.0 177119.0 True False 220273.69044639848 257784.00733705497 219427.13008174815 249466.6405946255 353418.50849300576 211151.035437881 277243.4040330487 328985.6904859036 241616.25924473372 209229.27262676717 1.052786198035171 1.2320647302392624 1.0487401085276074 1.1923123254346708 1.6891446596167736 1.009184961487401 1.325069864997372 1.572369326507976 1.154791852073873 1.0 17.674725183187512 -6.010600411011989 24.923381782553875 1.3199892274685716 1.1228241489651258 0.12040154566885575 0.2118034690117183 917.2609701340256 2156645.651510672 0.05882418572620975 0.08130389106891646 9.758871264599572e-07 6.010600411011989 -0.19716507850344578 (ac)S(ph)ETAPAAPAAPAPAEKTPVK ddPTM_PC-9_Lapatinib_30min_R1 6 SETAPAAPAAPAPAEKTPVK 20 1 P10412 P10412 HIST1H1E Histone H1.4 1 S(0.495)ET(0.495)APAAPAAPAPAEKT(0.009)PVK;S(0.338)ET(0.338)APAAPAAPAPAEKT(0.324)PVK;S(0.499)ET(0.499)APAAPAAPAPAEKT(0.001)PVK;S(0.499)ET(0.499)APAAPAAPAPAEKT(0.003)PVK;S(0.5)ET(0.5)APAAPAAPAPAEKTPVK;S(0.389)ET(0.389)APAAPAAPAPAEKT(0.221)PVK 128.36 5.0904e-05 2264813400.0 548012.0 879725.0 855398.0 792484.0 704971.0 652771.0 809764.0 762864.0 700331.0 605599.0 True False 540197.248386907 877688.0508126417 785070.4783717685 850765.9170091255 663505.9918063126 624853.5060135227 851689.6177143177 798309.4464119535 621452.3479676305 710275.9802400555 0.7605455673783786 1.2357000310161201 1.1053034316413661 1.1977962660677162 0.9341523721273303 0.8797334041935896 1.1990967474733807 1.1239426203630665 0.8749449020613018 1.0 19.43802017223915 -6.276717455838058 24.878548048716013 1.01191915382326 1.0885028237331678 0.04694013081159687 0.15213802061298548 2600.632528861199 4234812.95798099 0.04745944562689938 0.05402510756777265 5.287891605892792e-07 6.276717455838058 0.07658366990990784 (ac)S(ph)ETAPAETATPAPVEK ddPTM_PC-9_AZD4547_30min_R2 4 SETAPAETATPAPVEK 16 0 P16401 P16401 HIST1H1B Histone H1.5 1 S(0.992)ET(0.008)APAETATPAPVEK;S(0.981)ET(0.019)APAETATPAPVEK;S(0.94)ET(0.06)APAETATPAPVEK;S(0.856)ET(0.144)APAETATPAPVEK 114.69 2.9725e-05 25909800.0 119918.0 203561.0 193800.0 274088.0 217207.0 174290.0 159231.0 190078.0 159623.0 163782.0 True False 158049.42955064806 269358.11239768413 191230.08537332946 210901.24621738735 187051.55731573357 163391.61874771793 173402.25052867926 160705.81265791287 168060.34590318677 158048.0420313611 1.0000087790982357 1.7042799704170712 1.209949094689728 1.3344122679832926 1.18351075351264 1.0338098254662118 1.0971489953306188 1.0168162198809423 1.0633497495010975 1.0 17.270003637049406 -6.473515321684451 1.88421459714693 1.042359484147513 1.34106558194712 0.3675704098886643 0.1649908371306474 0.3423447749584812 2.4326066497509853 0.05771486146048381 0.06494785856731276 3.361125109625276e-07 6.473515321684451 0.298706097799607 (ac)S(ph)ETAPAETATPAPVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SETAPAETATPAPVEK 16 0 P16401 P16401 HIST1H1B Histone H1.5 1 S(0.979)ET(0.021)APAETATPAPVEK;S(0.969)ET(0.031)APAETATPAPVEK;S(0.986)ET(0.014)APAETATPAPVEK 125.73 2.808e-05 8041800.0 98953.0 100358.0 113191.0 133577.0 214023.0 104173.0 140295.0 122798.0 116031.0 79792.0 True False 115703.78848916298 110320.87899708388 115889.90271925819 126093.11375247673 172086.72952696096 98709.98449391437 127005.24195215927 119574.68261523568 117727.73386591431 94257.65796687549 1.22752666451594 1.17041820661249 1.2295011908739002 1.3377492765286936 1.8257055526187227 1.0472357007703665 1.3474262430410917 1.268593822448434 1.24899914134602 1.0 16.52432221450391 -9.016458438379223 0.9664695981305894 0.9992598170411185 1.3159007848156357 0.18674850139025934 0.19251364376977265 3.147328033845794 4.410653327237499 0.19480405100165465 0.06192501183430788 9.62812148886599e-10 9.016458438379223 0.3166409677745171 (ac)S(ph)ETAPAETATPAPVEK ddPTM_PC-9_Lapatinib_30min_R1 3 SETAPAETATPAPVEK 16 0 P16401 P16401 HIST1H1B Histone H1.5 1 S(0.971)ET(0.029)APAETATPAPVEK;S(0.648)ET(0.351)APAET(0.001)ATPAPVEK;S(0.886)ET(0.114)APAETATPAPVEK 123.76 4.7622e-05 13012800.0 153586.0 166758.0 171312.0 106079.0 111458.0 132369.0 140732.0 150476.0 131896.0 99810.0 True False 151395.835475777 166371.88209658128 157227.38864344356 113880.40352917027 104902.25957485902 126707.88643720985 148018.41435303557 157467.66429964555 117040.48355354615 117062.02551153483 1.29329588151419 1.421228458755719 1.3431118072354813 0.9728210581658606 0.8961254438957438 1.082399573076963 1.2644443294589194 1.3451643571990757 0.9998159782568724 1.0 16.836913621229378 -5.701938856151267 8.975517761850723 1.094748697970764 1.3608415174612414 0.4720928131176234 0.13131576169813775 0.3198788754740938 44.59338599811914 0.039876112929729084 0.06904268303412617 1.9863745571897507e-06 5.701938856151267 0.2660928194904775 (ac)S(ph)ETAPAETATPAPVEKSPAK ddPTM_PC-9_AZD4547_30min_R2 6 SETAPAETATPAPVEKSPAK 20 1 P16401 P16401 HIST1H1B Histone H1.5 1 S(0.748)ET(0.169)APAET(0.052)AT(0.004)PAPVEKS(0.027)PAK;S(0.969)ET(0.024)APAET(0.001)AT(0.001)PAPVEKS(0.006)PAK;S(0.848)ET(0.149)APAET(0.002)ATPAPVEKS(0.001)PAK;S(0.584)ET(0.11)APAET(0.066)AT(0.006)PAPVEKS(0.234)PAK;S(0.731)ET(0.07)APAET(0.07)AT(0.085)PAPVEKS(0.043)PAK;S(0.93)ET(0.041)APAET(0.001)AT(0.004)PAPVEKS(0.023)PAK 102.64 1.9768e-09 5731640700.0 294910.5 345985.3 286756.3 339493.1 351632.2 302186.1 341139.7 265217.3 280414.0 314960.8 True False 388685.90448053257 457818.2821136985 282953.72409876174 261228.21091110905 302814.13864358765 283290.35539652203 371500.47242483264 224234.06037225405 295236.1115634732 303934.11825860676 1.2788492016214301 1.5063076325118496 0.9309705857307091 0.8594895907304465 0.9963150579427014 0.9320781655565247 1.2223059212744785 0.737771927867148 0.9713819338711663 1.0 18.21339910875625 -5.268762902283895 24.991173513766164 0.9535321373504014 1.3925784245599049 0.6572643720822473 0.12600875553077767 281.16704985079593 959471.7321337648 0.03206930124537767 0.06895030871718988 5.3856372449510085e-06 5.268762902283895 0.43904628720950345 (ac)S(ph)ETAPAETATPAPVEKSPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 SETAPAETATPAPVEKSPAK 20 1 P16401 P16401 HIST1H1B Histone H1.5 1 S(0.659)ET(0.34)APAET(0.001)ATPAPVEKSPAK;S(0.858)ET(0.022)APAET(0.025)AT(0.001)PAPVEKS(0.094)PAK;S(0.647)ET(0.052)APAET(0.294)ATPAPVEKS(0.007)PAK;S(0.951)ET(0.048)APAETATPAPVEKSPAK;S(0.891)ET(0.106)APAET(0.003)ATPAPVEKSPAK;S(0.627)ET(0.022)APAET(0.003)AT(0.001)PAPVEKS(0.347)PAK;S(0.612)ET(0.078)APAET(0.275)AT(0.003)PAPVEKS(0.032)PAK 110.84 2.2339e-47 268781900.0 167063.0 148276.1 139512.4 194468.0 332528.0 198785.0 227105.0 278257.0 193924.0 140027.0 True False 195343.46625534384 162995.97128539387 142838.9047197232 183572.58843376246 267371.52547222056 188360.36465900755 205591.97030218595 270953.04858766194 196759.7716318363 165412.78664687803 1.1809453804339902 0.9853891865890418 0.8635300064477762 1.1097847521646065 1.61638970536784 1.1387291664526384 1.2429025256740407 1.6380417383699029 1.1895076288864994 1.0 17.33571123566319 -6.013136390995577 23.990459533791867 1.3282982139602608 1.0040247535216649 0.30766563995191465 0.20014897352227495 389.81780692674425 711911.8625936205 0.05616462387583464 0.07617085226728253 9.702052246272844e-07 6.013136390995577 -0.32427346043859595 (ac)S(ph)ETAPAETATPAPVEKSPAK ddPTM_PC-9_Lapatinib_30min_R1 6 SETAPAETATPAPVEKSPAK 20 1 P16401 P16401 HIST1H1B Histone H1.5 1 S(0.787)ET(0.045)APAET(0.032)AT(0.004)PAPVEKS(0.131)PAK;S(0.706)ET(0.086)APAET(0.086)AT(0.014)PAPVEKS(0.108)PAK;S(0.946)ET(0.046)APAET(0.005)ATPAPVEKS(0.003)PAK;S(0.932)ET(0.042)APAET(0.001)ATPAPVEKS(0.024)PAK;S(0.787)ET(0.165)APAET(0.046)AT(0.001)PAPVEKSPAK;S(0.502)ET(0.489)APAET(0.003)AT(0.001)PAPVEKS(0.005)PAK 112.03 2.2406999999999997e-11 3004658000.0 624535.0 589510.0 572807.0 488542.0 429193.0 425909.0 485500.0 487521.0 452434.0 364469.0 True False 615629.0163743065 588145.0258143862 525713.0195589628 524471.0084083368 403948.7115659037 407693.86491237086 510636.81443025527 510173.0054429111 401476.11857876746 427466.9810255852 1.440179110202337 1.3758841078281645 1.2298330465142926 1.2269275328588376 0.9449822547620962 0.9537435240827855 1.194564345543433 1.1934793284358394 0.9391979647540025 1.0 18.70545346016543 -5.588077397431672 1.3787207945715696 1.0549435135912977 1.4313689112197636 0.6908166071565399 0.09612968143808191 0.3021819996278726 1.0889758782141952 0.033428117714931746 0.10397378556349905 2.581800036276024e-06 5.588077397431672 0.37642539762846594 (ac)S(ph)ETAPLAPTIPAPAEK ddPTM_PC-9_AZD4547_30min_R2 3 SETAPLAPTIPAPAEK 16 0 P16402 P16402 HIST1H1D Histone H1.3 1 S(0.5)ET(0.5)APLAPTIPAPAEK;S(0.5)ET(0.5)APLAPTIPAPAEK;S(0.498)ET(0.498)APLAPT(0.004)IPAPAEK 65.295 0.00054901 6951700.0 48333.0 66420.0 66432.0 89941.0 78055.0 69815.0 63409.0 69749.0 61785.0 66771.0 True False 63701.8886111467 87888.9660861079 65551.06827410225 69206.49202459802 67218.41057737365 65449.45701343689 69052.27816049028 58970.89472257048 65050.82896342257 64433.367613510614 0.9886475124697575 1.364028753134409 1.0173466125082258 1.074078456363137 1.0432236132770292 1.0157696149923603 1.0716850712302544 0.9152229179808578 1.0095829439432014 1.0 15.97552037881517 -5.404625760010678 21.685657747114792 1.0199954060652374 1.1799526609645508 0.31153369798705854 0.09387805477099186 7.207822781502822 1302.1884116840386 0.022857965703624902 0.047582757988350745 3.93889351358105e-06 5.404625760010678 0.15995725489931334 (ac)S(ph)ETAPLAPTIPAPAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SETAPLAPTIPAPAEK 16 0 P16402 P16402 HIST1H1D Histone H1.3 1 S(0.497)ET(0.497)APLAPT(0.006)IPAPAEK;S(0.75)ET(0.25)APLAPTIPAPAEK 62.298 0.00019291 4779400.0 29191.0 26876.0 31262.0 35046.0 55343.0 32910.0 36079.0 40158.0 29354.0 23676.0 True False 34132.45975146948 29544.07166270381 32007.404641795238 33082.48624066501 44498.93643304966 31184.141665256084 32661.335930660105 39103.895050918116 29783.246717687947 27968.27138088712 1.2203993334673815 1.056342426757685 1.144418409200233 1.1828577386900225 1.5910506526141341 1.1149828046422139 1.1677995928264668 1.3981520172762922 1.0648940834448974 1.0 14.771503468283512 -4.354707037915243 20.742315669885656 1.2069852297497812 42.64320824184377 0.0 0.16860418977571906 13170.261256565922 1628043.5022835387 0.04045603102296257 58130.20092862588 4.418684180767987e-05 4.354707037915243 41.43622301209399 (ac)S(ph)FEGGDGAGPAMLATGTAR ddPTM_PC-9_AZD4547_30min_R2 2 SFEGGDGAGPAMLATGTAR 19 0 Q96B36-3 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 S(1)FEGGDGAGPAMLATGTAR;S(1)FEGGDGAGPAMLATGTAR 107.72 3.3246999999999995e-05 6479300.0 782.69 460.15 853.19 2960.3199999999997 2361.3 1343.49 485.14 875.54 695.74 1751.76 True False 1031.5691390366499 608.8844887763101 841.8761431355578 2277.863960488074 2033.4742540049006 1259.4813579171 528.3165201592882 740.2454109076733 732.5153960186386 1690.4314155942457 0.6102401608964522 0.3601947308594392 0.4980244305502385 1.3475045124426568 1.2029321244541964 0.7450650445196254 0.3125335433816263 0.43790325006912584 0.43333044408733606 1.0 10.723175768867781 -10.132570038377846 20.77824573798216 0.999999999999963 0.6690394811782104 0.08447825515731044 0.33396164720854626 0.0 0.0 0.36761530648953206 0.0891598081323618 7.369363205315672e-11 10.132570038377846 -0.3309605188217526 (ac)S(ph)FEGGDGAGPAMLATGTAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFEGGDGAGPAMLATGTAR 19 0 Q96B36-3 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 S(1)FEGGDGAGPAMLATGTAR;S(1)FEGGDGAGPAMLATGTAR 108.96 8.0959e-05 5875300.0 596.45 1654.41 1400.67 1344.2 1415.8 1652.97 1672.5500000000002 1522.05 2019.16 706.44 True False 697.417204575519 1818.6488911852136 1434.067284870555 1268.8888319551995 1138.3841534053392 1566.2853433126206 1514.1139557866225 1482.0978002452791 2048.686395124574 834.5119798240371 0.8357186253007111 2.179296325462804 1.718450207476876 1.5205160173048131 1.3641315893935708 1.8768877873303667 1.8143705451728618 1.7760054212256968 2.454951450255459 1.0 9.704788950097978 -6.786936712491459 24.853673441654347 1.8348139560375643 1.5706999745456873 0.06616828288629317 0.4543938534116855 605.298919436978 590014.0584898245 0.1535363493518926 0.1354574647596923 1.633289941523627e-07 6.786936712491459 -0.2641139814918769 (ac)S(ph)FEGGDGAGPAMLATGTAR ddPTM_PC-9_Lapatinib_30min_R1 2 SFEGGDGAGPAMLATGTAR 19 0 Q96B36-3 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 S(0.999)FEGGDGAGPAMLATGTAR;S(1)FEGGDGAGPAMLATGTAR 98.169 1.6616e-07 4612100.0 2721.9900000000002 3382.82 3882.38 1291.4 3878.13 2840.62 3163.9 4020.6 2860.85 2739.64 True False 2683.1739234481697 3374.9872881298434 3563.185702820189 1386.3738639841122 3650.0260180969362 2719.1333044086405 3327.711260918406 4207.411753921925 2538.63094691395 3213.183123659165 0.8350516668942845 1.050356347037705 1.1089270563460578 0.43146431766556553 1.135953314089455 0.8462428687575385 1.035643202659678 1.3094217142316291 0.7900673099586566 1.0 11.64978748895927 -7.367572132153004 6.306520443180096 1.062375078840391 0.9072135529016295 0.07416442852253513 0.22092513901623798 0.608501335570818 31.029062650535966 0.09169673620104163 0.061301889782198915 4.289709353588344e-08 7.367572132153004 -0.15516152593876142 (ac)S(ph)GDEMIFDPTMSK ddPTM_PC-9_AZD4547_30min_R2 10 SGDEMIFDPTMSK 13 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK 86.014 8.4511e-05 471383500.0 1043739.0 1039181.7 1377550.6 1778269.0 1561731.2 1487531.9 1134721.2 1522328.2 1253164.7 1326008.3 True False 1375626.2908801401 1375076.8622192699 1359283.3789684293 1368316.556032176 1344911.7803227762 1394516.2951395304 1235709.1885537591 1287087.356311918 1319404.42765556 1279585.1530225126 1.0750564646915202 1.074627084388402 1.062284425352749 1.0693438828983524 1.0510529738063585 1.0898190650661572 0.9657107896531045 1.005862996512334 1.0311188939157274 1.0 20.287244727452247 -7.2537141796864315 24.99994123113798 1.001161752500789 1.0692663670985416 0.7928787473163645 0.017443657165865864 266.49419432408615 862418.0949714876 0.006730319605490674 0.005114485134811792 5.5755256782673406e-08 7.2537141796864315 0.06810461459775263 (ac)S(ph)GDEMIFDPTMSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 SGDEMIFDPTMSK 13 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK 94.363 3.9424e-05 568408200.0 1613548.2 1763805.3 1769318.6 1965293.4 2117718.7 1728013.6 1962642.5 1840637.1 1669994.7 1422901.2 True False 1886690.0412303845 1938904.2336008651 1811505.8656021545 1855184.382365172 1702766.9229058907 1637393.5248219152 1776726.794098795 1792322.326441214 1694415.2131679282 1680861.9238802944 1.1224539115473167 1.1535178506065962 1.077724374540097 1.1037101596557388 1.013032003827553 0.9741392208123605 1.057033161889464 1.0663114566267355 1.0080632972257149 1.0 20.6807697871078 -5.980668097462821 1.772351950643589 1.0229979615956561 1.128415916173097 0.6831688809157241 0.03120660497241671 0.22181984950747946 1.406313743445539 0.010825484726707513 0.018126182398369627 1.045518934923756e-06 5.980668097462821 0.10541795457744074 (ac)S(ph)GDEMIFDPTMSK ddPTM_PC-9_Lapatinib_30min_R1 14 SGDEMIFDPTMSK 13 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 S(0.998)GDEMIFDPT(0.002)MSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(0.999)GDEMIFDPT(0.001)MSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(0.999)GDEMIFDPT(0.001)MSK;S(1)GDEMIFDPTMSK;S(0.999)GDEMIFDPT(0.001)MSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK 121.9 9.1943e-05 258035330.0 969344.5 958687.8999999999 1031922.1 879566.8 1016108.7999999999 1000529.2999999999 904530.1000000001 925516.6 1060606.4 809776.2 True False 955521.4696739902 956468.11706916 947081.4482725003 944253.0766208288 956343.2781307631 957738.9941867136 951362.2426782302 968519.4800004619 941149.7385514778 949744.9372110359 1.0060821934780904 1.0070789320318643 0.9971955744809159 0.9942175415998172 1.006947487331813 1.008417056688033 1.0017028840100413 1.019767984070079 0.9909499926529767 1.0 19.857180590798023 (ac)S(ph)GDEMIFDPTMSKK ddPTM_PC-9_AZD4547_30min_R2 5 SGDEMIFDPTMSKK 14 1 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 S(1)GDEMIFDPTMSKK;S(0.997)GDEMIFDPT(0.002)MSKK;S(1)GDEMIFDPTMSKK;S(0.982)GDEMIFDPT(0.008)MS(0.009)KK;S(0.995)GDEMIFDPT(0.004)MS(0.001)KK 93.561 0.00074598 510991000.0 492507.0 322489.0 568682.0 1066595.0 883946.0 586916.0 445047.0 597807.0 452410.0 640906.0 True False 649113.9812180103 426727.262633888 561140.9051097821 820708.0014784805 761225.3559186128 550216.04973857 484655.3208297201 505429.6643882438 476323.4689866792 618468.0760166052 1.0495513129776843 0.6899745988221885 0.9073077930294272 1.3270013979774848 1.2308240076375012 0.8896434126113201 0.7836383794475879 0.8172283808787465 0.7701666221069273 1.0 19.238339602765087 -6.984855297885757 24.57699102990174 0.828829271909775 1.0329364703061195 0.23378066573492928 0.1715321089571208 319.9731385597544 519253.52028916375 0.06749157509418148 0.05950013376646102 1.035487122055944e-07 6.984855297885757 0.2041071983963445 (ac)S(ph)GDEMIFDPTMSKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SGDEMIFDPTMSKK 14 1 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 S(1)GDEMIFDPTMSKK;S(1)GDEMIFDPTMSKK;S(1)GDEMIFDPTMSKK;S(0.992)GDEMIFDPT(0.007)MS(0.001)KK;S(0.995)GDEMIFDPT(0.004)MS(0.001)KK 57.148999999999994 0.004308 260456100.0 153722.0 83361.4 124031.0 204295.0 192051.0 242679.0 175050.0 234743.0 201312.0 166026.0 True False 179744.098452105 91636.96887570008 126988.36943018685 192849.01348332677 154419.98519963917 229952.48602803654 158467.9967477495 228581.24498076783 204255.80715511309 196125.19953890672 0.9164763063323126 0.467237096972444 0.6474862471968845 0.9832954354499966 0.7873541266633909 1.1724780220423396 0.8079940625697776 1.1654863603359782 1.0414562108047387 1.0 17.58141538943717 -5.765857273759505 10.355022221119434 0.9920939283915415 0.6559039556885368 0.46149935421938715 0.15638180929093587 0.10122474712829284 170.56030697026358 0.04197959158070255 0.06614308997357336 1.7145206738288382e-06 5.765857273759505 -0.33618997270300477 (ac)S(ph)GDEMIFDPTMSKK ddPTM_PC-9_Lapatinib_30min_R1 10 SGDEMIFDPTMSKK 14 1 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 S(1)GDEMIFDPTMSKK;S(1)GDEMIFDPTMSKK;S(1)GDEMIFDPTMSKK;S(0.998)GDEMIFDPT(0.002)MSKK;S(1)GDEMIFDPTMSKK;S(0.998)GDEMIFDPT(0.002)MSKK;S(0.995)GDEMIFDPT(0.004)MS(0.001)KK;S(0.998)GDEMIFDPT(0.001)MSKK;S(1)GDEMIFDPTMSKK;S(1)GDEMIFDPTMSKK 79.65899999999999 0.00063384 566256400.0 1968057.0 1011708.0 1148301.0 927208.0 861542.0 959739.0 648434.0 628956.0 1153184.0 638277.0 True False 1939992.146282546 1009365.4522851523 1053892.1243500423 995397.9693952131 810867.7934167421 918693.200230881 682006.7397080712 658179.5918767642 1023300.274354132 748602.3289993563 2.591485587382155 1.3483333048594086 1.4078130450899902 1.329675223861171 1.0831756220964674 1.2272112504096564 0.9110400987126206 0.8792112532651901 1.366947756790925 1.0 19.513840011093862 -2.3062356735453853 0.9639355771864231 1.1032059278825421 199.99999999999997 0.8594716968742531 0.17405573989926051 82.51472253282994 0.7460241888936009 0.056528907142092265 35454.96047090112 0.004940425179127607 2.3062356735453853 198.89679407211742 up (ac)S(ph)GDHLHNDSQIEADFR ddPTM_PC-9_Lapatinib_30min_R1 1 SGDHLHNDSQIEADFR 16 0 P11387 P11387 TOP1 DNA topoisomerase 1 1 S(0.999)GDHLHNDS(0.001)QIEADFR 132.32 5.792100000000001e-47 6444600.0 2592.7 2605.6 2977.5 1626.3 3107.9 2604.7 3107.4 2455.6 2399.6 0.0 True False 2555.727622557051 2599.5668932875865 2732.701443482378 1745.9035271777623 2925.0994323664927 2493.303052852259 3268.285967375026 2569.696140608534 2129.33177909178 0.0 0.0 (ac)S(ph)GEDEQQEQTIAEDLVVTK ddPTM_PC-9_AZD4547_30min_R2 16 SGEDEQQEQTIAEDLVVTK 19 0 Q9UQ80;F8VR77 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 1 S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(0.998)GEDEQQEQT(0.002)IAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(0.999)GEDEQQEQT(0.001)IAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK 145.71 9.559799999999999e-88 54029600.0 309376.73000000004 280552.7 366821.5 525528.6 469741.7 406377.5299999999 349177.31999999995 448464.9 350180.4 385328.55 True False 407752.09470425657 371235.8737679314 361957.20723308943 404376.1006059318 404526.1732869582 380966.6788077302 380253.4250338992 379164.95440319006 368690.2210365442 371838.3147493822 1.0965843984611434 0.9983798308093752 0.9734263331013842 1.087505199345796 1.0879087959496792 1.0245492831057512 1.0226311005367716 1.0197038319161542 0.9915337027197968 1.0 18.504315909704815 -7.716004474029035 1.465065291430059 0.9978180245799693 1.0430179724964639 0.20531885208179068 0.037677146430767076 0.8154098302169074 3.283665425507147 0.031724271435527675 0.012772159205775622 1.923071917643211e-08 7.716004474029035 0.04519994791649462 (ac)S(ph)GEDEQQEQTIAEDLVVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 13 SGEDEQQEQTIAEDLVVTK 19 0 Q9UQ80;F8VR77 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 1 S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK 143.98 3.997899999999999e-59 42954300.0 278880.30000000005 288746.1 299432.89999999997 355294.4 401818.0 358387.49999999994 339450.8 344349.6 329220.39999999997 267862.8 True False 326089.22665300133 317410.904551505 306572.51594159746 335388.40664798627 323084.6473746486 339593.0285948637 307295.56281302945 335310.78786856023 334034.62552619417 316424.2052392415 1.0305445071954984 1.0031182801313114 0.9688655635867194 1.05993284045513 1.0210490917734036 1.0732207681081314 0.9711506190896172 1.0596875407020112 1.0556544663630831 1.0 18.271500439111392 -5.769254224428559 24.998449841579394 1.0352997466142901 1.0010703314727525 0.18290127392395794 0.03244720133262699 282.5414587409715 903806.7790003134 0.00886990413685775 0.013420049539262917 1.7011624016921053e-06 5.769254224428559 -0.034229415141537656 (ac)S(ph)GEDEQQEQTIAEDLVVTK ddPTM_PC-9_Lapatinib_30min_R1 10 SGEDEQQEQTIAEDLVVTK 19 0 Q9UQ80;F8VR77 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 1 S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK 178.15 2.8579999999999997e-59 55057120.0 387257.35 327563.31 408497.56000000006 342853.3 372172.0 362207.7 319707.3 328528.41 403443.1 299867.38 True False 381734.9891747004 326804.8572811244 374912.46746298217 368067.8754070804 350281.57467830455 346716.9210183886 336260.1796541671 343793.03928052593 358003.0896338148 351699.0570848323 1.0854023674070392 0.9292173257157661 1.066003618464495 1.0465421160293298 0.9959696155620178 0.9858340931939378 0.9561020221133513 0.9775205032682264 1.0179245079621069 1.0 18.42398194149881 -6.444167738626834 5.212427547467902 0.984701513657218 1.0267559530937316 0.20199216112005436 0.041354443649622916 0.38482309991122005 18.336269003393305 0.012837782072558132 0.014438013493477356 3.5961041511388405e-07 6.444167738626834 0.04205443943651355 (ac)S(ph)GGKYVDSEGHLYTVPIR ddPTM_PC-9_AZD4547_30min_R2 4 SGGKYVDSEGHLYTVPIR 18 1 Q03135 Q03135 CAV1 Caveolin-1 1 S(0.949)GGKY(0.051)VDSEGHLYTVPIR;S(0.867)GGKY(0.133)VDSEGHLYTVPIR;S(0.789)GGKY(0.211)VDSEGHLYTVPIR;S(0.869)GGKY(0.131)VDSEGHLYTVPIR 94.569 4.912e-05 36491500.0 76863.0 57224.8 136135.0 250867.0 208671.0 107025.0 86421.0 126674.0 81273.0 119521.0 True False 101303.83515028178 75721.5975080443 134329.7609509713 193033.48900651347 179700.63357364887 100332.70983116921 94112.30158033916 107099.44397893708 85568.92485788198 115336.60616936114 0.8783320275743719 0.6565270127408998 1.1646758597502034 1.6736532781540463 1.5580537657729854 0.8699121047817195 0.8159794596534594 0.9285815452352695 0.7419060409340633 1.0 16.81549095062951 -6.935152730860133 24.999664809884994 0.8624118883413614 1.1858286002104754 0.23830346817694426 0.2813668044140976 102.63249082684082 39565.410225918815 0.1144577191337545 0.1009422116446526 1.1610402322810069e-07 6.935152730860133 0.323416711869114 (ac)S(ph)GGKYVDSEGHLYTVPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGGKYVDSEGHLYTVPIR 18 1 Q03135 Q03135 CAV1 Caveolin-1 1 S(0.968)GGKY(0.032)VDSEGHLYTVPIR;S(0.849)GGKY(0.151)VDSEGHLYTVPIR 77.506 0.00022909 10964700.0 22264.0 9304.8 16893.9 35013.0 51276.0 52839.0 31092.0 48251.0 49291.0 30292.0 True False 26032.85546595583 10228.519050719091 17296.714646472527 33051.33512367756 41228.83588784588 50068.02982225664 28146.740673413435 46984.462376160416 50011.78762558956 35783.699808659934 0.7275059763287997 0.2858429705539758 0.4833685376012065 0.9236421974364675 1.1521680571964832 1.3991853858035046 0.7865799462860937 1.3130129815360738 1.3976136590964336 1.0 15.127014940210774 -5.9200731752678095 2.705025490097996 1.1796856738688137 0.47030237442255024 0.6925738866132714 0.2009054356962173 0.14716942931233495 2.1815202171116326 0.06043719455592101 0.0961713415043016 1.2020618794056326e-06 5.9200731752678095 -0.7093832994462634 (ac)S(ph)GGKYVDSEGHLYTVPIR ddPTM_PC-9_Lapatinib_30min_R1 4 SGGKYVDSEGHLYTVPIR 18 1 Q03135 Q03135 CAV1 Caveolin-1 1 S(0.896)GGKY(0.102)VDS(0.002)EGHLYTVPIR;S(0.841)GGKY(0.159)VDS(0.001)EGHLYTVPIR;S(0.927)GGKY(0.073)VDSEGHLYTVPIR;S(0.852)GGKY(0.148)VDSEGHLYTVPIR 92.264 2.8463000000000002e-05 29864500.0 305466.0 111939.0 120761.0 68592.0 75541.4 64700.2 40201.6 36383.6 118585.0 28387.9 True False 301109.99882439605 111679.81212301167 110832.49673094031 73636.4844962042 71098.2033721067 61933.12326953266 42283.04214006048 38074.114880862006 105228.70854459016 33294.71069050094 9.043778803889815 3.354280899484559 3.3288319505524666 2.2116571361952952 2.135420368508899 1.8601490142157122 1.2699627437256553 1.1435484523289352 3.1605232892025747 1.0 15.023005383672293 -3.0251901863223365 0.9552352657554429 1.813006385986375 199.9999999747287 0.9030549037624701 0.6939335185099677 13.600158326707499 0.5665111338995756 0.21828588640538593 5367.463258383272 0.0009436475434769414 3.0251901863223365 198.18699358874233 up (ac)S(ph)GPDVETPSAIQICR ddPTM_PC-9_AZD4547_30min_R2 1 SGPDVETPSAIQICR 15 0 O00154-2;O00154-3;O00154-4 O00154-2 1 S(1)GPDVETPSAIQICR 61.958 0.0054901 0.0 522.89 642.08 1055.8 447.85 689.03 396.9 853.87 1077.9 533.22 998.44 True False 689.1581432123497 849.6198034412548 1041.799402152535 344.60510171352547 593.3700780235448 372.08178025686607 929.8627758346277 911.3353226778694 561.4049206097947 963.4849195014837 0.7152765230294696 0.8818195139793742 1.081282520427587 0.3576652781361928 0.6158581893845938 0.3861832943367549 0.9651036119130413 0.9458739874718569 0.5826815856134738 1.0 9.91211827536091 -10.758935951362261 11.317621952789983 1.000000000608974 0.7302652914822397 0.11109875475895814 0.23240819973388513 3.909804641185911e-09 1.5486665401538018e-10 0.2352464184929419 0.057055637146744435 1.7420637695503643e-11 10.758935951362261 -0.26973470912673425 (ac)S(ph)KGPAVGIDLGTTYSCVGVFQHGK ddPTM_PC-9_AZD4547_30min_R2 3 SKGPAVGIDLGTTYSCVGVFQHGK 24 1 P11142;E9PKE3;P11142-2;E9PNE6;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65;E9PPY6;E9PN25 P11142 HSPA8 Heat shock cognate 71 kDa protein 1 S(0.659)KGPAVGIDLGT(0.157)T(0.14)Y(0.033)S(0.01)CVGVFQHGK;S(0.694)KGPAVGIDLGT(0.034)T(0.104)Y(0.117)S(0.052)CVGVFQHGK;S(0.985)KGPAVGIDLGT(0.005)T(0.005)Y(0.004)SCVGVFQHGK 70.352 3.2835e-07 3680800.0 21701.399999999998 17432.980000000003 24853.5 36109.6 29654.100000000002 28706.9 23033.100000000002 28661.5 27965.399999999998 32240.199999999997 True False 28601.993782838603 23067.849864495576 24523.926351011596 27785.089607758677 25537.140082025475 26911.85300492776 25083.001278972883 24232.523750748434 29443.59395150438 31111.480411153145 0.9193388872805 0.7414578014174469 0.7882597043572386 0.8930815647653336 0.8208269019840879 0.8650135785656841 0.8062297565878892 0.77889330338846 0.9463900001669209 1.0 14.925159425370433 -8.429890085612994 4.3857372903863014 0.998451969168458 0.8255431519482564 0.5760443588898585 0.05116267220891155 0.14032230745073856 4.372825960341513 0.04831990901720279 0.012641362224451943 3.7162927181879375e-09 8.429890085612994 -0.17290881722020157 (ac)S(ph)KGPAVGIDLGTTYSCVGVFQHGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKGPAVGIDLGTTYSCVGVFQHGK 24 1 P11142;E9PKE3;P11142-2;E9PNE6;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65;E9PPY6;E9PN25 P11142 HSPA8 Heat shock cognate 71 kDa protein 1 S(0.651)KGPAVGIDLGT(0.07)T(0.222)Y(0.046)S(0.012)CVGVFQHGK 47.391999999999996 0.0015865999999999999 2063800.0 13701.0 11585.0 11380.0 15077.0 18771.0 14054.0 14120.0 15207.0 13691.0 11449.0 True False 16020.308692915061 12735.082237402285 11651.342358890326 14232.284570293514 15092.95729875098 13316.983499346976 12782.451380052677 14807.832363148356 13891.204974172704 13524.613069765875 1.1845299093050052 0.9416226676289484 0.861491733537041 1.0523247132377953 1.1159622253808592 0.9846480214001054 0.9451251073960635 1.0948802961506605 1.0271055373278175 1.0 13.723299699641093 (ac)S(ph)KGPAVGIDLGTTYSCVGVFQHGK ddPTM_PC-9_Lapatinib_30min_R1 1 SKGPAVGIDLGTTYSCVGVFQHGK 24 1 P11142;E9PKE3;P11142-2;E9PNE6;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65;E9PPY6;E9PN25 P11142 HSPA8 Heat shock cognate 71 kDa protein 1 S(0.715)KGPAVGIDLGT(0.117)T(0.14)Y(0.027)S(0.001)CVGVFQHGK 52.483000000000004 0.0010550000000000002 2469600.0 6971.8 6162.3 10323.0 8701.8 8989.9 9086.8 7901.3 6558.9 7000.6 5220.7 True False 6872.380853528468 6148.0315729605845 9474.282787932358 9341.75940035384 8461.131756823426 8698.17874636538 8310.390652642178 6863.650438441649 6212.1187084138655 6123.091038854523 1.1223711700380203 1.0040731934161684 1.5473039234289678 1.5256607065083667 1.3818399405027126 1.4205535555768238 1.3572214752170082 1.120945351765612 1.0145396612584088 1.0 12.580044418076845 -7.898760661115631 3.18618439250523 1.0172825972683388 1.3451287516227137 0.4285245099140741 0.15743362488844967 0.27188568031206595 5.3700012424114 0.11564720613185782 0.048040858248828866 1.2625231170567231e-08 7.898760661115631 0.3278461543543749 (ac)S(ph)KSESPKEPEQLR ddPTM_PC-9_AZD4547_30min_R2 2 SKSESPKEPEQLR 13 2 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8W646 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 S(0.772)KS(0.228)ESPKEPEQLR;S(0.333)KS(0.333)ES(0.333)PKEPEQLR 77.533 0.0031092 55051500.0 114830.0 54245.0 100799.0 263501.0 197298.0 125797.0 75775.0 88001.0 64329.0 131666.0 True False 151343.55138762252 71778.63543120936 99462.3393991033 202754.91549986758 169906.5783113786 117930.89370363575 82518.82820437431 74402.46751180556 67729.29960974373 127056.41341601123 1.1911523969442592 0.5649351614875984 0.7828202978895781 1.5957865490504792 1.3372530653377277 0.9281774176759069 0.6494660598846682 0.5855860834682557 0.5330647842858809 1.0 16.95510967446365 -7.125485833166867 3.940848246346208 0.6586770871593576 1.0795518230416636 0.29458487069734873 0.28976893052422587 0.32915745079070985 8.834326397496957 0.1265918691247694 0.09678998186173396 7.490557925659547e-08 7.125485833166867 0.42087473588230606 (ac)S(ph)KSESPKEPEQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SKSESPKEPEQLR 13 2 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8W646 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 S(0.466)KS(0.466)ES(0.067)PKEPEQLR;S(0.74)KS(0.242)ES(0.019)PKEPEQLR 64.84100000000001 0.00093113 27077900.0 56088.0 46948.8 33865.6 71136.0 59810.0 61188.0 62120.0 79637.0 56460.0 52151.0 True False 65582.59061150426 51609.56659019009 34673.08434000321 67150.4805460237 48090.65984967743 57979.19356468214 56235.54389014676 77546.61313237634 57285.62068817406 61605.56347291111 1.0645562983989572 0.8377419778472376 0.5628239137078827 1.0900067584894466 0.7806220272755661 0.941135675030007 0.9128322300773106 1.2587599035024613 0.9298773918911302 1.0 15.91077302320249 -7.54755795061231 24.640136262161366 1.0737505865768422 0.8731592454446697 0.20913304927306897 0.1596148805742242 277.23308503160365 276790.1869694308 0.07323875155175204 0.042286754452502975 2.834275413269743e-08 7.54755795061231 -0.20059134113217247 (ac)S(ph)KSESPKEPEQLR ddPTM_PC-9_Lapatinib_30min_R1 1 SKSESPKEPEQLR 13 2 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8W646 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 S(0.819)KS(0.181)ESPKEPEQLR 117.31 0.00018730000000000003 6110100.0 24694.0 26938.0 26749.0 27057.0 34031.0 29050.0 22854.0 25805.0 24297.0 22506.0 True False 24341.859031675027 26875.626716065784 24549.800474125997 29046.862039506053 32029.363487520233 27807.599218857526 24037.268294519163 27003.99450578401 21560.416001247286 26396.132112640033 0.9221752235441609 1.0181653357916078 0.9300529475062786 1.100421149415171 1.2134112433913253 1.0534724974172105 0.910636005000471 1.023028464570114 0.8168020946873077 1.0 14.688038923120619 -7.254578783685639 24.14368727646252 0.9395356795033822 1.0443248173084925 0.22195745067805062 0.09327877925583464 559.6509587481049 1969518.5487351965 0.03842804979951229 0.029057850799471575 5.5644368280123513e-08 7.254578783685639 0.10478913780511023 (ac)S(ph)LSHLYR ddPTM_PC-9_AZD4547_30min_R2 2 SLSHLYR 7 0 Q9UBB9;F6UKU9;F6SQZ1;F6XM96;F6UQ07 Q9UBB9 TFIP11 Tuftelin-interacting protein 11 1 S(0.998)LS(0.002)HLYR;S(0.999)LS(0.001)HLYR 65.672 0.0052173 0.0 4161.0 5109.4 5872.700000000001 7851.6 6289.9 6646.3 6715.4 7048.6 5008.5 4758.700000000001 True False 5484.11144582338 6760.913630237268 5794.824160845989 6041.534926010758 5416.655956577069 6230.705810333109 7313.05759054641 5959.40083071456 5273.239084944598 4592.099361435553 1.1942492995423712 1.4722925394462096 1.261911754242715 1.315636803669268 1.1795598331486776 1.3568316623674506 1.592530347222332 1.2977508458901397 1.1483286117955671 1.0 12.164938143291426 -8.433479812831777 2.695521140908941 1.0060621857246346 1.340383883626549 0.46505165936618353 0.11693493056575209 0.2271004862762965 3.380047427343763 0.1147960151949412 0.03116051652347497 3.68570173581028e-09 8.433479812831777 0.33432169790191435 (ac)S(ph)LSHLYR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSHLYR 7 0 Q9UBB9;F6UKU9;F6SQZ1;F6XM96;F6UQ07 Q9UBB9 TFIP11 Tuftelin-interacting protein 11 1 S(0.999)LS(0.001)HLYR 72.485 0.0038391 0.0 3397.3 2764.6 4376.3 3517.0 3395.2 3375.6 3017.0 3950.0 3661.2 2821.6 True False 3348.8538790114835 2758.198738556519 4016.4975070065266 3775.6519123680664 3195.5010112200257 3231.2334569079326 3173.205497705626 4133.531420183952 3248.837101854819 3309.3098004543276 1.0119493431989133 0.8334664642693326 1.213696434965113 1.140918239763988 0.9656095089016213 0.9764070612138893 0.9588722993749282 1.249061486965188 0.9817264921551901 1.0 11.692314640276882 (ac)S(ph)LYPSLEDLKVDK ddPTM_PC-9_AZD4547_30min_R2 1 SLYPSLEDLKVDK 13 1 B4DHN5;E9PBU7;O00560-2;O00560 B4DHN5 SDCBP Syntenin-1 1 S(0.963)LY(0.036)PS(0.001)LEDLKVDK 144.65 0.0001008 4081300.0 11406.0 14812.0 20062.0 32673.0 31124.0 27209.0 28584.0 28964.0 28099.0 30531.0 True False 15032.87074046178 19599.689335552986 19795.964771722072 25140.744642817957 26802.969839346348 25507.616928720265 31127.920625454684 24488.27932650691 29584.25577475456 29462.11898291314 0.5102440441972368 0.6652504983405989 0.671912457593527 0.8533243877468077 0.9097434524275395 0.8657767264979709 1.0565404560176965 0.8311784817890777 1.0041455535466495 1.0 14.84657357557844 -5.248531443332229 0.6320445274357337 0.9659415816350281 0.38071360282796984 0.8467343236656028 0.0646430316772331 0.7592719356429143 0.34063956574699755 0.03232940625765558 0.2965690133430091 5.642460879145007e-06 5.248531443332229 -0.5852279788070582 (ac)S(ph)LYPSLEDLKVDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLYPSLEDLKVDK 13 1 B4DHN5;E9PBU7;O00560-2;O00560 B4DHN5 SDCBP Syntenin-1 1 S(0.409)LY(0.227)PS(0.364)LEDLKVDK;S(0.947)LY(0.05)PS(0.002)LEDLKVDK 112.71 0.00043459 3805900.0 22053.6 19565.2 30810.0 45294.0 52920.0 45513.0 47134.0 46192.0 45078.0 42445.0 True False 25786.83890154527 21507.50375409781 31544.627247575692 42756.32402512928 42550.70588939862 43126.21815894256 42669.126299391144 44979.5089444696 45737.18047080251 50139.9425055649 0.51429733687236 0.4289495096989939 0.6291316996240002 0.8527397896474227 0.8486389046951147 0.8601170245489631 0.8510007025767015 0.897079388144042 0.9121905248640096 1.0 15.613672721413684 -5.626923958249688 2.35820990423095 0.8851808359290194 0.4698973753591789 0.9303864801961155 0.04702316527344983 0.06592132056458866 0.7378526812296174 0.013207851209759171 0.02789901725927049 2.3608915716385482e-06 5.626923958249688 -0.4152834605698405 (ac)S(ph)LYPSLEDLKVDK ddPTM_PC-9_Lapatinib_30min_R1 3 SLYPSLEDLKVDK 13 1 B4DHN5;E9PBU7;O00560-2;O00560 B4DHN5 SDCBP Syntenin-1 1 S(0.733)LY(0.243)PS(0.024)LEDLKVDK;S(0.853)LY(0.036)PS(0.111)LEDLKVDK;S(0.965)LY(0.025)PS(0.009)LEDLKVDK 131.52 4.8211e-05 14279200.0 69272.0 60315.0 64710.0 59139.0 67368.0 63901.0 51519.0 56196.0 64564.0 47768.0 True False 68284.16857707087 60175.34432324253 59389.793587823566 63488.279341920745 63405.546690584015 61168.10319050653 54186.40173559696 58807.07131358412 57292.12243093916 56024.635153140924 1.2188239761029955 1.0740872146468392 1.0600656911996682 1.133220754912161 1.131744035766903 1.0918072562776386 0.9671888373298777 1.049664511921185 1.0226237488978485 1.0 15.773773728113888 -7.091042395788977 5.447748044430153 1.0145395307424443 1.117382801140367 0.5931458291245344 0.044391224862030884 0.1780934680108856 8.288234263106043 0.01723882738567389 0.013366285223030317 8.108818957709374e-08 7.091042395788977 0.10284327039792274 (ac)S(ph)MPDAMPLPGVGEELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SMPDAMPLPGVGEELK 16 0 O43865 O43865 AHCYL1 Putative adenosylhomocysteinase 2 1 S(1)MPDAMPLPGVGEELK 55.452 0.025934 0.0 5711.5 8173.4 7836.8 9654.0 12942.0 10546.0 9221.6 10651.0 11060.0 8775.6 True False 6678.344142732968 8984.801135881202 8023.659033229503 9113.11767869029 10406.108004924361 9992.949194828037 8348.063289397573 10371.422535667329 11221.731576535687 10366.546812388622 0.6442207095184252 0.8667110946862118 0.7739953504710717 0.8790890393510391 1.0038162363274588 0.9639612279458273 0.8052887273340776 1.0004703324421282 1.0824946609149606 1.0 13.339647779360492 -3.4631393325242774 0.34141827887028164 1.006109615550248 2.558723334229107e-15 0.6351973258514464 0.07640952471678866 11.80575043409655 0.5439086158332928 0.07335274061015487 5.85435156490625 0.0003442394724189305 3.4631393325242774 -1.0061096155502454 (ac)S(ph)NGYEDHMAEDCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SNGYEDHMAEDCR 13 0 Q15717;M0QZR9 Q15717 ELAVL1 ELAV-like protein 1 1 S(0.937)NGY(0.063)EDHMAEDCR;S(0.903)NGY(0.097)EDHMAEDCR;S(0.555)NGY(0.445)EDHMAEDCR 61.211999999999996 0.0039683 0.0 566.54 1749.86 1224.49 1847.3899999999999 1884.9 1197.5300000000002 2070.91 1495.73 2313.34 814.21 True False 662.4440323249472 1923.5745363781407 1253.6864855041854 1743.8867276191907 1515.567375867865 1134.7294186689196 1874.7384127099772 1456.4686723569337 2347.1682210906934 961.8198277171862 0.6887402538760435 1.9999322959931214 1.3034525275692483 1.8131116424977296 1.5757289797871612 1.1797733691580496 1.9491575851160619 1.5142843081263597 2.440340855377807 1.0 9.909622857155329 -7.27540177989721 24.515232070683467 1.7688026851800582 1.47156555712832 0.07918918775863448 0.47667850638211073 1656.1532225706214 2907866.0669401553 0.18568896631434123 0.12593890743963254 5.3039353294390456e-08 7.27540177989721 -0.2972371280517383 (ac)S(ph)NGYEDHMAEDCR ddPTM_PC-9_Lapatinib_30min_R1 1 SNGYEDHMAEDCR 13 0 Q15717;M0QZR9 Q15717 ELAVL1 ELAV-like protein 1 1 S(0.636)NGY(0.364)EDHMAEDCR 41.68899999999999 0.022241999999999998 0.0 0.0 0.0 545.67 0.0 644.31 621.85 559.83 0.0 579.71 0.0 True False 0.0 0.0 500.8071189471127 0.0 606.4129525621979 595.2549251031513 588.8152581307727 0.0 514.4169551830703 0.0 0.0 (ac)S(ph)NPSPQVPEEEASTSVCRPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNPSPQVPEEEASTSVCRPK 20 1 F2Z390;A0A140TA04;A0A0A0MRT5;Q9UBC1-3;Q9UBC1 F2Z390 NFKBIL1 NF-kappa-B inhibitor-like protein 1 1 S(0.675)NPS(0.325)PQVPEEEASTSVCRPK;S(0.681)NPS(0.319)PQVPEEEASTSVCRPK 118.24 1.2612999999999997e-60 0.0 5155.1 4114.2 4306.7 5694.8 7225.5 4485.2 4091.45 4930.3 5417.1 4049.67 True False 6027.756612133893 4522.630586199438 4409.388061250704 5375.73881879071 5809.715143685746 4249.988216256657 3703.878236467178 4800.884849084653 5496.314839353659 4783.8431138299175 1.260023890563607 0.9453969284913789 0.9217250558454398 1.1237280761255828 1.2144451658312267 0.8884045975441993 0.7742474300127862 1.003562352453714 1.1489329203677294 1.0 12.223954361779436 -6.785090228633623 24.999778216362678 0.9514532383291535 1.0770449514539042 0.18686921862644923 0.13245466248338558 453.67248704077525 479544.2175371629 0.049681703757857285 0.04383992231997851 1.640248961138359e-07 6.785090228633623 0.1255917131247507 (ac)S(ph)NPSPQVPEEEASTSVCRPK ddPTM_PC-9_Lapatinib_30min_R1 3 SNPSPQVPEEEASTSVCRPK 20 1 F2Z390;A0A140TA04;A0A0A0MRT5;Q9UBC1-3;Q9UBC1 F2Z390 NFKBIL1 NF-kappa-B inhibitor-like protein 1 1 S(0.749)NPS(0.251)PQVPEEEASTSVCRPK;S(0.655)NPS(0.345)PQVPEEEASTSVCRPK;S(0.664)NPS(0.336)PQVPEEEASTSVCRPK 161.25 4.592899999999998e-137 3317700.0 15355.2 15296.4 18533.5 13012.2 13994.3 14550.8 13723.2 15896.300000000001 15294.5 11635.1 True False 15136.232032201198 15260.982125608009 17009.747171378884 13969.160595426723 13171.182787852385 13928.496203571496 14433.720147866698 16634.900130296242 13571.872351774966 13646.211532203764 1.109189315765854 1.1183310539774016 1.246481276597354 1.0236658403294445 0.9651896980176252 1.0206859369504544 1.057708955617791 1.219012331081008 0.9945523942485162 1.0 13.736212864591005 -5.788306838827114 24.999673808366357 1.046043407880944 1.1540336832854114 0.3471133350737925 0.07371500144308593 270.6485836527108 251832.45473300072 0.021994441969969913 0.03263229461501255 1.6281453048738095e-06 5.788306838827114 0.10799027540446748 (ac)S(ph)QERPTFYR ddPTM_PC-9_Lapatinib_30min_R1 1 SQERPTFYR 9 1 Q16539-5;Q16539-3;Q16539-4;Q16539-2;Q16539;B5TY33 Q16539-5 MAPK14 Mitogen-activated protein kinase 14 1 S(0.998)QERPT(0.002)FYR 82.671 0.0038303000000000005 31893000.0 0.0 0.0 5058.7 0.0 7747.9 11164.0 7543.7 0.0 0.0 0.0 True False 0.0 0.0 4642.7932131467 0.0 7292.18375495748 10686.541744555085 7934.275874392415 0.0 0.0 0.0 0.0 (ac)S(ph)QGDSNPAAIPHAAEDIQGDDR ddPTM_PC-9_AZD4547_30min_R2 1 SQGDSNPAAIPHAAEDIQGDDR 22 0 P68402-3;P68402-2;P68402-4;P68402 P68402-3 PAFAH1B2 Platelet-activating factor acetylhydrolase IB subunit beta 1 S(0.962)QGDS(0.038)NPAAIPHAAEDIQGDDR 106.82 1.2214e-32 13592000.0 34491.0 31654.0 47345.0 65055.0 51254.0 43473.0 41655.0 50070.0 37942.0 53498.0 True False 45458.4205426326 41885.53647229236 46717.17436532657 50057.57483973076 44138.266808439075 40754.62643765872 45362.21430357246 42332.83199413755 39947.536659871774 51625.05130352391 0.8805496439192811 0.8113413045544667 0.904932260321796 0.9696372899548836 0.8549776841660244 0.7894350786800443 0.8786860866611099 0.8200056159798513 0.7738013939202607 1.0 15.655783689791997 -6.507325122839951 24.664097779336537 0.8404938294632124 0.8900168761725383 0.05788154275147317 0.06871452820465973 1426.7733046187354 2262504.4756413363 0.021268013775763032 0.02337111564635128 3.1093877064140785e-07 6.507325122839951 0.049523046709325946 (ac)S(ph)QGDSNPAAIPHAAEDIQGDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQGDSNPAAIPHAAEDIQGDDR 22 0 P68402-3;P68402-2;P68402-4;P68402 P68402-3 PAFAH1B2 Platelet-activating factor acetylhydrolase IB subunit beta 1 S(0.5)QGDS(0.5)NPAAIPHAAEDIQGDDR 72.523 2.9196e-05 9441500.0 25636.0 27162.0 25111.0 34884.0 28526.0 31566.0 34886.0 33640.0 29295.0 24733.0 True False 29975.668465920062 29858.463852595676 25709.741473997805 32929.56257545394 22936.535075604406 29910.62339123288 31581.345527232123 32756.98564452627 29723.38395430497 29216.89711367972 1.0259702920980296 1.0219587568255346 0.8799613926819142 1.127072544607617 0.785043496794368 1.0237440093263137 1.080927430601292 1.1211657937895478 1.017335408296595 1.0 14.834515349052756 -6.993941335267114 24.999878127936714 1.0631516760802464 0.9678899945509603 0.16867745855629002 0.09086748423725423 255.44609877196208 1054040.3309815337 0.030860571628382086 0.02714604403675201 1.014048354684308e-07 6.993941335267114 -0.09526168152928616 (ac)S(ph)QGDSNPAAIPHAAEDIQGDDR ddPTM_PC-9_Lapatinib_30min_R1 1 SQGDSNPAAIPHAAEDIQGDDR 22 0 P68402-3;P68402-2;P68402-4;P68402 P68402-3 PAFAH1B2 Platelet-activating factor acetylhydrolase IB subunit beta 1 S(0.5)QGDS(0.5)NPAAIPHAAEDIQGDDR 110.35 3.3020000000000004e-15 10177000.0 42233.0 44318.0 42999.0 33933.0 38960.0 40543.0 32306.0 33275.0 49066.0 32686.0 True False 41630.74967541634 44215.38439388982 39463.788200939984 36428.546017169654 36668.44939830711 38809.07040034905 33978.646605527996 34821.077976359746 43539.670392114225 38335.73154864268 1.0859516172945007 1.1533726528157335 1.0294257239063236 0.9502504464000361 0.9565084039619793 1.012347197577429 0.8863440250882874 0.9083191208227412 1.135746433764241 1.0 15.226402090149023 -5.47399786849356 3.940750792403553 0.9718369096800084 1.118047129962044 0.4129946283707452 0.06619539700619767 0.19909967645746865 6.351239383138683 0.017747001570892467 0.03774786807437115 3.3573926203879997e-06 5.47399786849356 0.14621022028203567 (ac)S(ph)QKQEEENPAEETGEEKQDTQEK ddPTM_PC-9_AZD4547_30min_R2 1 SQKQEEENPAEETGEEKQDTQEK 23 2 A6NMQ3;Q5T5H1;O43768-2;O43768;O43768-9;O43768-3;O43768-4;A0A1W2PRU0;O43768-8 A6NMQ3 ENSA Alpha-endosulfine 1 S(0.995)QKQEEENPAEET(0.005)GEEKQDTQEK 40.381 0.027405000000000002 14806000.0 14959.0 14697.0 34804.0 67769.0 46968.0 36558.0 22521.0 44792.0 30712.0 30478.0 True False 19715.65083347078 19447.51783450056 34342.476219470394 52145.90407061269 40447.30392669385 34272.022480802494 24525.325371042018 37870.425617763314 32335.373620209328 29410.974496781204 0.6703501387085457 0.661233371802384 1.167675563529148 1.7730083740108524 1.375245282373098 1.1652800720545078 0.8338834666537867 1.2876290658749825 1.0994322416534745 1.0 14.844066966507576 -5.284402567705858 5.37823036177225 1.236037874954861 0.6609636417108431 0.4629033279389426 0.23526869536123457 0.1500703367553078 13.947987267332842 0.06699936737503273 0.15378744318895934 5.195142114463038e-06 5.284402567705858 -0.575074233244018 (ac)S(ph)QKQEEENPAEETGEEKQDTQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQKQEEENPAEETGEEKQDTQEK 23 2 A6NMQ3;Q5T5H1;O43768-2;O43768;O43768-9;O43768-3;O43768-4;A0A1W2PRU0;O43768-8 A6NMQ3 ENSA Alpha-endosulfine 1 S(1)QKQEEENPAEETGEEKQDTQEK 59.574 0.00043583 14449000.0 27454.0 36771.0 26709.0 34687.0 32252.0 32327.0 34450.0 28992.0 21405.0 26047.0 True False 32101.41995878332 40421.381868926976 27345.84385444656 32743.5998467713 25932.452122919203 30631.715211568935 31186.646603598794 28230.990719563164 21718.007630718486 30769.114912061457 1.0433000770587522 1.3136998572903975 0.8887432717061037 1.0641710020048658 0.8428078674682226 0.9955344929197603 1.0135698310702355 0.9175106531418832 0.7058379057307577 1.0 14.909195324022175 -5.274985484075108 24.9787387820488 0.9327899544979203 1.1784999730819987 0.4332950663742897 0.11426987994804665 611.754862187774 1128063.7508170882 0.029056047726044143 0.061008658415277056 5.309021888900371e-06 5.274985484075108 0.24571001858407837 (ac)S(ph)QKQEEENPAEETGEEKQDTQEK ddPTM_PC-9_Lapatinib_30min_R1 3 SQKQEEENPAEETGEEKQDTQEK 23 2 A6NMQ3;Q5T5H1;O43768-2;O43768;O43768-9;O43768-3;O43768-4;A0A1W2PRU0;O43768-8 A6NMQ3 ENSA Alpha-endosulfine 1 S(1)QKQEEENPAEETGEEKQDTQEK;S(0.997)QKQEEENPAEET(0.003)GEEKQDTQEK;S(0.996)QKQEEENPAEET(0.004)GEEKQDTQEK 60.621 0.0010019999999999999 38830000.0 42738.0 46142.0 39777.4 41164.0 44637.6 43691.5 37969.4 40948.8 36421.5 33969.5 True False 42128.548282810676 46035.16103395606 36507.055717204326 44191.33787907852 42012.10412889817 41822.91639486105 39935.269746298974 42851.430738943935 32319.327134602107 39841.08281348646 1.0574147414625463 1.1554696253981547 0.9163168553452683 1.1091901815509762 1.054492025871265 1.0497434668292633 1.0023640655866068 1.0755588882849956 0.811206042915626 1.0 15.281969237508113 -8.243120445628039 24.957977880838413 0.90560300816254 1.0516408643233792 0.3934195563533708 0.07298756919549083 658.1073020096012 896618.4353290056 0.04638363755791229 0.017457116179503917 5.7132016687260855e-09 8.243120445628039 0.1460378561608392 (ac)S(ph)REMQDVDLAEVKPLVEK ddPTM_PC-9_AZD4547_30min_R2 2 SREMQDVDLAEVKPLVEK 18 2 Q92597;E5RJ98;E5RI76;E5RIR1;E5RGM5;E5RIM2 Q92597 NDRG1 Protein NDRG1 1 S(1)REMQDVDLAEVKPLVEK;S(1)REMQDVDLAEVKPLVEK 61.495 0.014594 11643900.0 28634.0 23530.4 40620.0 61667.0 54548.0 44516.0 29661.0 38820.0 34256.0 42035.0 True False 37739.016375800675 31136.141637948695 40081.35225936351 47450.62589565253 46974.95176701792 41732.407482778166 32300.771539029243 32821.260994855606 36066.70222498994 40563.36744445822 0.9303718787025063 0.7675926235804301 0.9881169829956866 1.1697901058294717 1.1580634135304182 1.02882009339882 0.7963039948115103 0.8091355097625076 0.8891446765206221 1.0 15.307889804912366 -7.251358115247722 24.60796872110431 0.8577406711303442 1.0096285706578916 0.22861512072042667 0.11863370877466553 865.5625586180249 2112807.5719135148 0.05192832431800864 0.03972195671487455 5.605855317055739e-08 7.251358115247722 0.15188789952754733 (ac)S(ph)RHEGVSCDACLK ddPTM_PC-9_AZD4547_30min_R2 2 SRHEGVSCDACLK 13 1 Q9P0J7 Q9P0J7 KCMF1 E3 ubiquitin-protein ligase KCMF1 1 S(1)RHEGVSCDACLK;S(1)RHEGVSCDACLK 85.958 0.00013048 15537400.0 21976.0 15452.4 38044.0 56837.0 50044.0 39763.0 29439.0 43779.0 31030.0 35787.0 True False 28963.91087080379 20447.086111848424 37539.511702492004 43734.1077728964 43096.25442231873 37276.61332414657 32059.013969100226 37013.96149133913 32670.182450999455 34534.10802271505 0.8387044730314903 0.5920838059115124 1.087027111799156 1.266403282926259 1.247933040400866 1.0794143951720896 0.9283290000718474 1.0718088177344245 0.9460265320740415 1.0 15.075734340485104 -5.273772156835251 24.48041080305168 1.088382703637695 0.715394148951619 0.5972505323576967 0.11899977419605585 344.79042934443703 684405.4610086207 0.03349660956436267 0.0705669146060736 5.323874915449725e-06 5.273772156835251 -0.37298855468607595 (ac)S(ph)RHEGVSCDACLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRHEGVSCDACLK 13 1 Q9P0J7 Q9P0J7 KCMF1 E3 ubiquitin-protein ligase KCMF1 1 S(0.671)RHEGVS(0.329)CDACLK 46.481 0.0038814 6656200.0 38530.0 31917.0 47235.0 63465.0 55414.0 58597.0 58278.0 52703.0 52360.0 51373.0 True False 45052.36799781164 35085.50882789543 48361.261539735024 59909.26180630611 44556.024492727396 55524.070165877 52757.48594381801 51319.60209344431 53125.665944611974 60686.51823155575 0.7423785267414688 0.5781433809404423 0.7969028863248931 0.9871922718933399 0.73419971669357 0.9149325382948995 0.8693444191758755 0.8456507901413788 0.8754113350498285 1.0 15.889088430778742 -5.484500444571949 6.319451499605259 0.8781466064073998 0.6646763931843048 0.5643243073181103 0.07971828271696954 0.13705240947432712 15.662017934837097 0.019648922791198217 0.04008662710965035 3.277174413322102e-06 5.484500444571949 -0.213470213223095 (ac)S(ph)RHEGVSCDACLK ddPTM_PC-9_Lapatinib_30min_R1 2 SRHEGVSCDACLK 13 1 Q9P0J7 Q9P0J7 KCMF1 E3 ubiquitin-protein ligase KCMF1 1 S(1)RHEGVSCDACLK;S(1)RHEGVSCDACLK 80.102 0.00010149 14970400.0 32926.0 31730.0 44105.0 32527.0 38267.0 36172.0 31379.0 34614.0 37905.0 24474.0 True False 32456.469202111115 31656.5311344854 40478.85715022341 34919.14408689114 36016.210295816665 34625.00788105038 33003.65108137383 36222.292804619574 33635.739742654565 28704.29829044488 1.1307180852741927 1.1028498524565313 1.410201940512096 1.2165127234103146 1.2547323028553456 1.2062656097946274 1.1497808010293749 1.261911802828404 1.1718014982394211 1.0 14.808979167251673 -8.592621631493207 8.186968771812808 1.000000171262798 1.2179323408755969 0.3897661042595377 0.08117226416145247 2.7592618751935594 324.1349029439765 0.07969847114637627 0.020598240271088312 2.554926250673364e-09 8.592621631493207 0.21793216961279893 (ac)S(ph)RLSWGYR ddPTM_PC-9_AZD4547_30min_R2 1 SRLSWGYR 8 1 Q8N1Q1 Q8N1Q1 CA13 Carbonic anhydrase 13 1 S(0.971)RLS(0.029)WGYR 54.787 0.012773999999999999 2426300.0 3718.1 5046.5 5073.9 9028.4 5576.2 9240.5 6252.7 7884.2 7674.6 6397.0 True False 4900.378458715673 6677.682435313812 5006.616770772634 6947.041867389515 4802.0408822183235 8662.690074234242 6809.1781869150755 6665.878050892337 8080.263687993571 6173.042977095262 0.7938351436881711 1.0817488976005816 0.8110451829591031 1.1253836872942782 0.7779049813902208 1.4033095357308671 1.1030505072101648 1.0798366503563497 1.3089595711507187 1.0 12.591766120187314 -6.751409511175208 24.999995412315204 1.1792722675453557 0.9326628819189545 0.42161884429398 0.1523907530849469 205.83103991325277 513044.44286326075 0.047306318923710906 0.04677151179368409 1.7725173252156272e-07 6.751409511175208 -0.24660938562640122 (ac)S(ph)SAPTTPPSVDKVDGFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSAPTTPPSVDKVDGFSR 18 1 Q16537-2;Q16537 Q16537-2 PPP2R5E Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform 1 S(0.496)S(0.496)APT(0.006)T(0.001)PPSVDKVDGFSR;S(0.249)S(0.249)APT(0.249)T(0.249)PPS(0.002)VDKVDGFSR 84.169 0.00083974 13251600.0 26756.3 26833.1 31597.0 40711.0 46085.0 41990.0 42248.0 40616.0 38589.0 25176.6 True False 31285.61312898643 29496.91283422005 32350.392312289787 38430.09465684283 37054.97507394057 39787.970480829616 38245.9635909678 39549.87303620922 39153.291121784394 29740.918282144074 1.0519383709738972 0.9917956316745431 1.0877401970373053 1.29216234321573 1.2459257216744288 1.3378191656145875 1.2859711737256616 1.3298134462766158 1.3164788911474647 1.0 14.860161572354807 -5.663556003063484 3.8193545331266443 1.2764800160092427 1.0249829973835933 0.5221210575183807 0.09400406908086176 0.14969943341966946 4.11408121018936 0.024371605261656437 0.04401560882295489 2.1699213702181482e-06 5.663556003063484 -0.2514970186256493 (ac)S(ph)SAPTTPPSVDKVDGFSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSAPTTPPSVDKVDGFSR 18 1 Q16537-2;Q16537 Q16537-2 PPP2R5E Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform 1 S(0.479)S(0.479)APT(0.021)T(0.021)PPSVDKVDGFSR 73.36 0.00082521 3552400.0 14117.0 11518.0 13766.0 15772.0 12702.0 13205.0 10012.0 10211.0 14659.0 12956.0 True False 13915.688991259269 11491.33077866381 12634.212618296697 16931.92549384963 11954.893333092838 12640.252932358468 10530.372370907762 10685.440337088181 13007.949053886645 15195.427337215151 0.915781352010965 0.7562361046944939 0.8314483257311377 1.1142776782842836 0.7867428185987296 0.8318458343979046 0.6929961321402134 0.7032010419949459 0.8560436482117783 1.0 13.89134962753318 (ac)S(ph)SCSRVALVT(ph)GANRGIGLAIAR ddPTM_PC-9_AZD4547_30min_R2 1 SSCSRVALVTGANRGIGLAIAR 22 2 O75828 O75828 CBR3 Carbonyl reductase [NADPH] 3 2 S(0.334)S(0.334)CS(0.334)RVALVT(0.999)GANRGIGLAIAR 74.76899999999999 0.010182 0.0 20019.0 21337.0 24227.0 19552.0 20298.0 23671.0 21774.0 31382.0 21289.0 19395.0 True False 26384.625578932522 28233.767982223475 23905.734150359403 15044.58847538876 17479.97306898382 22190.84862801784 23711.843818172787 26532.632986619228 22414.293077645096 18715.98695337855 1.4097373355012761 1.5085374900374573 1.2772895284608017 0.8038362343842604 0.9339594600341604 1.1856627536284974 1.2669299181089888 1.417645409387809 1.1976014480817396 1.0 14.191983507680538 -5.521223407981263 24.979328851508185 1.1270088067271953 1.4425814969341983 0.40693753468017557 0.1660541747271864 67.73071690535566 1022068.147718046 0.05133279526082997 0.09062230372131794 3.011456484606772e-06 5.521223407981263 0.31557269020700307 (ac)S(ph)SDASQGVITTPPPPSMPHK ddPTM_PC-9_AZD4547_30min_R2 1 SSDASQGVITTPPPPSMPHK 20 0 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 S(0.333)S(0.333)DAS(0.333)QGVITT(0.002)PPPPSMPHK 69.456 2.554e-15 0.0 8115.9 9318.1 7377.0 13442.0 12421.0 11948.0 9272.1 12537.0 10666.0 8749.9 True False 10696.587378793067 12329.993599623034 7279.176159953823 10343.154576829766 10696.558552066606 11200.889671224591 10097.298937562222 10599.694721599817 11229.78298492944 8443.56866426228 1.2668325211905687 1.4602822680663679 0.8620971119431062 1.2249742955970209 1.2668291071452038 1.326558723757737 1.1958567921996557 1.2553572006186697 1.3299806552719722 1.0 13.043637165831276 -10.693425895279757 3.812783430274333 0.9998532808345904 1.2399488682238773 0.2013367153086899 0.14518153838280606 104352209.12423335 297657552.92503315 244554.4660808869 0.03635338549065662 2.0256952266242715e-11 10.693425895279757 0.24009558738928694 (ac)S(ph)SDASQGVITTPPPPSMPHK ddPTM_PC-9_Lapatinib_30min_R1 1 SSDASQGVITTPPPPSMPHK 20 0 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 S(0.333)S(0.333)DAS(0.333)QGVITTPPPPSMPHK 110.15 5.5481999999999995e-09 9605800.0 35419.0 43269.0 59139.0 46775.0 62727.0 77494.0 67125.0 64816.0 81917.0 62902.0 True False 34913.9185649509 43168.813288939426 54276.819703141686 50214.98953682583 59037.521186026934 74179.7622673371 70600.40405485261 67827.58798244124 72690.64483574816 73774.52688835347 0.4732516769343409 0.5851452406366341 0.7357122030112291 0.6806548500516795 0.8002426267723985 1.0054928902437679 0.9569753549446083 0.919390348447615 0.9853081802307508 1.0 16.170835143319035 -5.558771993480096 0.5208198552312261 0.9995700942609201 0.3554722210963674 0.9180856454636668 0.05157632406318553 0.596365291265402 0.21806636121791104 0.038807478098967715 0.21468317886488808 2.7620275522947234e-06 5.558771993480096 -0.6440978731645528 down (ac)S(ph)SILPFTPPIVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSILPFTPPIVK 12 0 P84022 P84022 SMAD3 Mothers against decapentaplegic homolog 3 1 S(0.5)S(0.5)ILPFTPPIVK;S(0.496)S(0.496)ILPFT(0.007)PPIVK 125.82 0.00057826 5017200.0 32252.9 38137.6 40281.0 40724.2 47773.2 37934.7 36609.6 36247.4 31573.2 29496.0 True False 37712.67894618789 41923.64888538225 41241.451806543184 38442.555103637795 38412.38440278567 35945.337551777295 33141.673657448744 35295.944157294914 32034.898319374002 34843.391309792474 1.0823481162004176 1.203202309231017 1.1836233574357207 1.1032954502575587 1.1024295557588322 1.0316256885613522 0.9511609637186643 1.0129881974885508 0.919396680838321 1.0 15.088597427932616 -6.725561994664026 1.3156625185810527 0.9678423512101592 1.1558068330276916 0.791475705920117 0.04037740761550192 0.1806681680616784 0.6561917837999771 0.018616579287809718 0.017353816301084433 1.881213147656575e-07 6.725561994664026 0.18796448181753245 (ac)S(ph)SILPFTPPVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSILPFTPPVVK 12 0 K7ESI8;K7EL92;K7ERC7;K7EJX0;B7Z5N5;Q15796-2;Q15796 K7ESI8 SMAD2 Mothers against decapentaplegic homolog;Mothers against decapentaplegic homolog 2 1 S(0.466)S(0.466)ILPFT(0.068)PPVVK 111.06 0.0027267 7399700.0 25659.0 33404.0 33479.0 36724.0 38254.0 28086.0 33368.0 29503.0 29889.0 20536.0 True False 30002.56191164932 36720.128360654766 34277.266329814534 34666.47334081442 30758.403308636694 26613.12071742273 30207.141476600395 28728.577511012427 30326.07008056736 24259.014237113435 1.2367593183464534 1.5136694344520105 1.4129702878600217 1.4290140976865744 1.2679164539826997 1.097040483891872 1.245192454291363 1.1842434004206603 1.2500949042757081 1.0 14.566233307414215 -6.451346198026048 3.743651595378478 1.17242393441054 1.4062789590382108 0.592429086907023 0.09404250352082937 0.1661634489433689 4.493931517240871 0.029328721055680906 0.03264398105009377 3.537152644001439e-07 6.451346198026048 0.23385502462767072 (ac)S(ph)SILPFTPPVVK ddPTM_PC-9_Lapatinib_30min_R1 1 SSILPFTPPVVK 12 0 K7ESI8;K7EL92;K7ERC7;K7EJX0;B7Z5N5;Q15796-2;Q15796 K7ESI8 SMAD2 Mothers against decapentaplegic homolog;Mothers against decapentaplegic homolog 2 1 S(0.393)S(0.393)ILPFT(0.213)PPVVK 94.69200000000001 0.0034571 3810000.0 11769.0 16517.0 18138.0 18309.0 18185.0 18941.0 18235.0 19990.0 16384.0 14899.0 True False 11601.171901829732 16478.75590130145 16646.76365470474 19655.504937033533 17115.394053085587 18130.937583627547 19179.119075459756 20918.808377082823 14538.661388831351 17474.272298330405 0.6639001443818737 0.9430295934484166 0.9526441714139519 1.1248253776445694 0.9794624783728987 1.0375789774867983 1.0975632488737308 1.1971204305361276 0.8320038248585871 1.0 14.092944756555038 -4.317129940511797 1.2004514871726844 1.0447937190943404 1.3677511307900524e-11 0.5712593215433492 0.0947763927368717 2.748675249392208 1.58223322471692 0.027276867829171852 4.6959267548428585 4.818036208547028e-05 4.317129940511797 -1.0447937190806629 (ac)S(ph)SILPFTPPVVKR ddPTM_PC-9_AZD4547_30min_R2 1 SSILPFTPPVVKR 13 1 K7ESI8;K7EL92;K7ERC7;K7EJX0;B7Z5N5;Q15796-2;Q15796 K7ESI8 SMAD2 Mothers against decapentaplegic homolog;Mothers against decapentaplegic homolog 2 1 S(0.499)S(0.499)ILPFT(0.003)PPVVKR 61.593 0.039024 21595000.0 26768.0 17324.0 40528.0 66021.0 54802.0 33308.0 26678.0 38291.0 27522.0 39985.0 True False 35279.667191011846 22923.64421071563 39990.57223947522 50800.87846428191 47193.68825137706 31225.245494572184 29052.290317865947 32374.00578964493 28976.756732723406 38585.1373204868 0.9143330733276952 0.5941055495102335 1.0364242559852757 1.3165918794672569 1.223105359438997 0.8092557824847528 0.7529399228661192 0.8390278754419758 0.7509823404810894 1.0 15.23575761970602 -6.877744808586901 21.253586434471874 0.8154791748038692 1.0117207123121175 0.19015630826568164 0.19100930207060235 5.503276541664776 986.9163390290471 0.0759659479546637 0.06699572528200304 1.3251199468810677e-07 6.877744808586901 0.19624153750824824 (ac)S(ph)SPAST(ph)PSRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPASTPSRR 10 1 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;E5RFR3;E5RG53;A0A3B3IS88 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 2 S(0.544)S(0.456)PAS(0.063)T(0.876)PS(0.061)RR 72.705 0.011634 0.0 0.0 0.0 0.0 0.0 555.35 0.0 0.0 0.0 0.0 513.21 True False 0.0 0.0 0.0 0.0 446.53315411333165 0.0 0.0 0.0 0.0 606.250910431875 0.0 0.0 0.0 0.0 0.736548426451409 0.0 0.0 0.0 0.0 1.0 9.243771198517836 -11.50333644103739 2.865638313462778 1.8028371202377853 0.08665275575830597 0.6112361533155501 0.21964379899411257 477097966.1371809 226278583.12737343 2535582644.217805 0.05798098450099307 3.138076733792669e-12 11.50333644103739 -1.7161843644794794 (ac)S(ph)SPASTPSRR ddPTM_PC-9_AZD4547_30min_R2 1 SSPASTPSRR 10 1 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;E5RFR3;E5RG53;A0A3B3IS88 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 S(0.5)S(0.5)PASTPSRR 80.916 0.0064091999999999994 62041000.0 0.0 0.0 0.0 0.0 808.4 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 696.1676139997303 0.0 0.0 0.0 0.0 0.0 0.0 (ac)S(ph)SPASTPSRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPASTPSRR 10 1 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;E5RFR3;E5RG53;A0A3B3IS88 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 S(0.499)S(0.499)PAS(0.002)TPSRR 55.111999999999995 0.023224 52637000.0 0.0 562.21 639.42 695.62 452.64 0.0 626.84 515.09 0.0 0.0 True False 0.0 618.0224932835504 654.6661978138537 656.6466666304683 363.9484413034277 0.0 567.4611772714042 501.5694332829673 0.0 0.0 0.0 (ac)S(ph)SPASTPSRR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPASTPSRR 10 1 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;E5RFR3;E5RG53;A0A3B3IS88 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 S(0.5)S(0.5)PASTPSRR 90.709 0.00040922 65222000.0 861.95 508.1 1919.4 0.0 344.66 552.19 0.0 871.22 1765.5 1581.7 True False 849.6584349377293 506.9235256675707 1761.594341098263 0.0 324.3877764276313 528.5741209177601 0.0 911.7000617449777 1566.6507984608008 1855.0947375172286 0.45801350074167757 0.27326018203577745 0.9495980477287633 0.0 0.1748631861582318 0.28493106590619666 0.0 0.4914574136333081 0.8445125560312529 1.0 10.857277150136875 -8.239688442748855 2.9081829829570522 0.9719101563844703 0.3091175341620652 0.4759627247662839 0.2558007098318626 0.23492432401276334 3.6995561095579172 0.2350461187789726 0.06877415873290516 5.758528986235623e-09 8.239688442748855 -0.6627926222224051 (ac)S(ph)SPPEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPPEGK 7 0 P51397;B4DQ75 P51397 DAP Death-associated protein 1 1 S(0.932)S(0.068)PPEGK 72.138 0.018135 11678000.0 23022.0 27740.0 24675.0 29915.0 36072.0 28432.0 29155.0 28743.0 26066.0 24854.0 True False 26919.16989477342 30493.843872726724 25263.345580458616 28238.959535738573 29003.950545018637 26940.975868324556 26393.22733607902 27988.52670572585 26447.165937972804 29359.83345584424 0.9168706605661963 1.038624552097272 0.8604730547417259 0.9618228788051061 0.9878785786928651 0.9176133750500483 0.898956984063726 0.9532931018774078 0.900794140326036 1.0 14.841556164041574 -5.250690882993936 24.997319877406316 0.93435932902514 0.9777475882178975 0.10871471432157886 0.04880297883616886 1569.7592200611634 3650704.633490521 0.011812421732371488 0.03059475548346284 5.614474542972809e-06 5.250690882993936 0.04338825919275757 (ac)S(ph)SPPEGKLETK ddPTM_PC-9_AZD4547_30min_R2 2 SSPPEGKLETK 11 1 P51397;B4DQ75 P51397 DAP Death-associated protein 1 1 S(0.5)S(0.5)PPEGKLETK;S(0.5)S(0.5)PPEGKLETK 82.749 0.0034113 1167620000.0 910042.0 531302.0 1026120.0 2533550.0 2191880.0 1068298.0 780013.0 978314.0 809594.0 1495980.0 True False 1199416.4259504955 703034.9813231144 1012512.9783451026 1949479.1904573012 1887575.2966028256 1001497.1571802737 849432.6459145956 827138.0507192467 852387.4860210909 1443606.1955408747 0.8308473804388954 0.48699914387642873 0.7013775512135048 1.3504231254195271 1.307541698306171 0.6937467851508101 0.5884102247125224 0.5729665425890913 0.5904570710862928 1.0 20.461245809315706 -6.970503171034812 24.998465045871498 0.6507585937559386 0.928582820492978 0.16985517202489564 0.2670719797826843 381.5850353315114 323390.98413030826 0.10510346796563597 0.09269149436815544 1.0702785681609564e-07 6.970503171034812 0.27782422673703944 (ac)S(ph)SPPEGKLETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPPEGKLETK 11 1 P51397;B4DQ75 P51397 DAP Death-associated protein 1 1 S(0.5)S(0.5)PPEGKLET(0.001)K 47.062 0.035345 406140000.0 29095.0 11249.0 16215.0 41601.0 45178.0 58949.0 47662.0 73639.0 49004.0 43887.0 True False 34020.20884755594 12365.72637794892 16601.62709572995 39270.23084226172 36325.69521298659 55857.61066621638 43147.1103170022 71706.05427697008 49720.590793540185 51843.36569069917 0.6562114244380406 0.23852090259192726 0.32022664567683196 0.7574784221485624 0.7006816538437726 1.077430254036099 0.8322590507418176 1.3831288405303965 0.9590540685606025 1.0 15.661871761114226 -6.359603224109766 1.1276537976322225 1.085870666846023 0.3890076721195678 0.6841754271588483 0.1830176439540132 0.26088206823737836 0.69305211697737 0.07857826827842267 0.10585634704931622 4.369148198106513e-07 6.359603224109766 -0.6968629947264551 (ac)S(ph)SPPEGKLETK ddPTM_PC-9_Lapatinib_30min_R1 4 SSPPEGKLETK 11 1 P51397;B4DQ75 P51397 DAP Death-associated protein 1 1 S(0.5)S(0.5)PPEGKLETK;S(0.5)S(0.5)PPEGKLETK;S(0.5)S(0.5)PPEGKLETK;S(0.5)S(0.5)PPEGKLETK 70.1 0.0004772 1822160000.0 9683890.0 3141860.0 5632810.0 5213820.0 3873880.0 4398530.0 2593550.0 2580480.0 5619620.0 3332270.0 True False 9545795.95279208 3134585.216205309 5169702.105075396 5597261.715593646 3646025.994741117 4210415.125374224 2727831.3286623876 2700378.521305386 4986679.218377953 3908248.4295293204 2.442474199098368 0.8020434915348548 1.32276701399404 1.4321663058322365 0.9329053821637988 1.0773151198787263 0.6979677412653388 0.6909434162123105 1.2759371130812456 1.0 21.898090745089668 -4.755879977288938 24.986470147700686 1.026568771570771 2.4424764627070417 0.7514308221549177 0.24444148040299693 93.1755609491608 418729.1143284932 0.0646667721422482 0.5510960128046211 1.7543652756348327e-05 4.755879977288938 1.4159076911362707 (ac)S(ph)SSAGSGHQPSQSR ddPTM_PC-9_AZD4547_30min_R2 2 SSSAGSGHQPSQSR 14 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 1 S(0.612)S(0.194)S(0.194)AGSGHQPSQSR;S(0.981)S(0.017)S(0.002)AGSGHQPSQSR 125.97 3.1156e-20 3976200.0 0.0 0.0 413.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 407.52335015059407 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)S(ph)SSAGSGHQPSQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSAGSGHQPSQSR 14 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 1 S(0.49)S(0.49)S(0.02)AGSGHQPSQSR;S(0.763)S(0.232)S(0.005)AGSGHQPSQSR 120.29 5.895499999999999e-27 2078870.0 0.0 0.0 418.81 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 428.7960187457698 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)S(ph)SSAGSGHQPSQSR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSAGSGHQPSQSR 14 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 1 S(0.767)S(0.225)S(0.008)AGSGHQPSQSR;S(0.548)S(0.446)S(0.006)AGSGHQPSQSR 136.81 1.2667999999999997e-56 2429100.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)S(ph)SSSSSPRETYEEDREYESQAK ddPTM_PC-9_AZD4547_30min_R2 1 SSSSSSPRETYEEDREYESQAK 22 2 B7WPG3;V9GYK2;Q8WVV9-2;Q8WVV9-5;Q8WVV9 B7WPG3 HNRNPLL Heterogeneous nuclear ribonucleoprotein L-like 1 S(0.168)S(0.168)S(0.168)S(0.168)S(0.148)S(0.148)PRET(0.028)Y(0.002)EEDREYESQAK 44.788000000000004 0.00011970000000000001 12410000.0 3897.0 5885.2 15045.0 18496.0 14121.0 7736.9 5219.7 11495.0 8326.5 8880.0 True False 5136.164937364504 7787.475808641402 14845.493469771634 14232.032960351384 12160.542896202607 7253.110419927815 5684.243188101244 9718.711878821872 8766.621791113346 8569.113902861644 0.5993811023622044 0.9087842566826876 1.732442074881745 1.6608523496926113 1.4191132285149823 0.846424788157577 0.6633408369333262 1.1341559919720896 1.0230488111712164 1.0 13.064930313499234 -6.766024756695439 24.98791328384166 0.924900471799964 1.292433216445125 0.19560180881366718 0.33264530360607997 202.79955506721308 1105144.1248518075 0.12858455884263212 0.11716652602164973 1.7138596071888386e-07 6.766024756695439 0.36753274464516106 (ac)S(ph)SVAVLTQESFAEHR ddPTM_PC-9_AZD4547_30min_R2 1 SSVAVLTQESFAEHR 15 0 Q00341;A0A024R4E5;C9JK79;C9JIZ1;C9J5E5;C9JZI8;C9JES8;C9JHZ8;C9JHS7;C9JT62;C9JHN6;C9JEJ8;C9JBS3;C9JQ82;C9JMQ6;C9J739;C9JHS9 Q00341 HDLBP Vigilin 1 S(0.831)S(0.169)VAVLTQESFAEHR 101.39 6.2184e-10 0.0 0.0 0.0 0.0 690.52 0.0 423.09 0.0 622.71 585.47 515.17 True False 0.0 0.0 0.0 531.3312824276514 0.0 396.63411541667324 0.0 526.4844779522548 616.4167489393056 497.13405510554423 0.0 0.0 0.0 1.0687887441443675 0.0 0.7978413696331177 0.0 1.0590392521801375 1.2399407013233825 1.0 8.957491125179638 -7.158982709738153 0.42074376125375407 1.167076613862049 4.275052466949433e-27 0.43458998398449866 0.3957166832405129 1.1958373976116954 0.47991942139917787 0.4212283206152271 0.4997906226096751 6.934534134417738e-08 7.158982709738153 -1.167076613862049 (ac)S(ph)SVAVLTQESFAEHR ddPTM_PC-9_Lapatinib_30min_R1 1 SSVAVLTQESFAEHR 15 0 Q00341;A0A024R4E5;C9JK79;C9JIZ1;C9J5E5;C9JZI8;C9JES8;C9JHZ8;C9JHS7;C9JT62;C9JHN6;C9JEJ8;C9JBS3;C9JQ82;C9JMQ6;C9J739;C9JHS9 Q00341 HDLBP Vigilin 1 S(0.5)S(0.5)VAVLTQESFAEHR 65.179 0.0069852000000000004 0.0 1029.9 867.82 930.0 1183.9 0.0 797.85 811.24 0.0 960.99 0.0 True False 1015.2134371394709 865.8106161087019 853.5389899038161 1270.9679553746246 0.0 763.7278153791896 853.242037772195 0.0 852.753186526675 0.0 0.0 (ac)S(ph)TGGDFGNPLRK ddPTM_PC-9_AZD4547_30min_R2 1 STGGDFGNPLRK 12 1 F5GX61;F5H3K7;P20340-3;P20340-2;P20340 F5GX61 RAB6A Ras-related protein Rab-6A 1 S(0.5)T(0.5)GGDFGNPLRK 64.654 0.0080827 4703300.0 13630.0 15086.0 17500.0 24745.0 16008.0 12715.0 14212.0 19741.0 14167.0 15001.0 True False 17964.05647838805 19962.25447719094 17267.938565703138 19040.42255643896 13785.56551819356 11919.929039974942 15476.840467707889 16690.48205305112 14915.838697496278 14475.819555949041 1.2409699090926751 1.3790068603740762 1.1928815842835396 1.3153260499585344 0.952316755877783 0.8234372495390964 1.069151242725146 1.1529904741173658 1.0303968379715265 1.0 13.821357408995917 -6.2587302881265865 24.999475367781052 1.0065228285187082 1.2826029859112436 0.6908475426853262 0.0908812385297046 153.3510956427732 1415122.352687217 0.029861226986400032 0.03682471711117222 5.511498732501091e-07 6.2587302881265865 0.27608015739253533 (ac)S(ph)TVHEILCK ddPTM_PC-9_AZD4547_30min_R2 5 STVHEILCK 9 0 P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YNP5;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 S(0.645)T(0.355)VHEILCK;S(0.5)T(0.5)VHEILCK;S(0.5)T(0.5)VHEILCK;S(0.5)T(0.5)VHEILCK;S(0.5)T(0.5)VHEILCK 61.961999999999996 0.0024905 64756100.0 220925.0 248446.0 366811.0 494551.0 429650.0 346121.0 326334.0 466594.0 370883.0 369984.0 True False 291174.5544745327 328751.31087366975 361946.8464699501 380539.90768678306 370000.5137988421 324477.9991541623 355377.09380727407 394492.6185634636 390487.1182073489 357030.9727743642 0.8155442431560376 0.9207921327358716 1.0137687597728184 1.065845645630515 1.0363260949706856 0.9088231103110074 0.9953676876988053 1.1049254788681158 1.0937065632513856 1.0 18.44568970927864 -4.964814146052018 2.0021465827821823 1.0285276394140306 0.7934725835197659 0.6225104884406955 0.0528763946678321 0.36702706388464373 2.15129857407292 0.016106180725255315 0.13975851364527656 1.0843908738825459e-05 4.964814146052018 -0.23505505589426468 (ac)S(ph)TVHEILCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 STVHEILCK 9 0 P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YNP5;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 S(0.5)T(0.5)VHEILCK;S(0.5)T(0.5)VHEILCK;S(0.5)T(0.5)VHEILCK;S(0.884)T(0.116)VHEILCK;S(0.5)T(0.5)VHEILCK 69.423 0.0016746999999999999 55888700.0 280920.0 280913.0 306733.0 319646.0 409039.0 303921.0 308403.0 316063.0 282680.0 221474.0 True False 328474.20757708856 308800.18615065905 314046.678011381 301737.27092631493 328890.744261031 287982.8477376572 279188.83519563667 307766.6811464295 286813.6602219804 261625.48301278043 1.2555130478671397 1.1803138692555195 1.2003673128280083 1.153317587612729 1.257105158387666 1.1007446385625563 1.067131656980059 1.1763635468621192 1.0962757026538181 1.0 17.997143544422812 -10.8275795750991 0.02728862474002448 2.0978162986023255e-09 2.0525719007250833 0.652248662696098 0.04621919504714082 488.1327736325821 2.2823940148866684 102.22957032253974 71.2107721902975 1.4873748197470118e-11 10.8275795750991 2.052571898627267 (ac)S(ph)TVHEILCK ddPTM_PC-9_Lapatinib_30min_R1 5 STVHEILCK 9 0 P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YNP5;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 S(0.5)T(0.5)VHEILCK;S(0.5)T(0.5)VHEILCK;S(0.5)T(0.5)VHEILCK;S(0.5)T(0.5)VHEILCK;S(0.5)T(0.5)VHEILCK 77.282 0.00069422 36819900.0 230767.0 278790.0 315230.0 234835.0 285995.0 227643.0 238638.0 224014.0 268296.0 193770.0 True False 227476.22026251562 278144.4788838072 289313.0062229889 252105.54928659537 269173.33638780355 217907.2395517515 250993.5079752984 234422.50824331373 238077.6791978699 227262.88631770416 1.0009387100035032 1.223888701716886 1.2730323499391853 1.1093124503143121 1.1844139654704124 0.9588333717064833 1.1044192566683317 1.0315037005892846 1.0475871492059072 1.0 17.7940025752349 -6.744976898348524 24.996158891425296 1.0351845814821727 1.1656106965868072 0.4196896787001173 0.07589726814350316 241.26569638612816 366330.0128942909 0.024932360977806895 0.024864507283198622 1.7989666059467965e-07 6.744976898348524 0.13042611510463442 (ac)S(ph)TVHEILCKLSLEGDHSTPPSAYGSVK ddPTM_PC-9_AZD4547_30min_R2 1 STVHEILCKLSLEGDHSTPPSAYGSVK 27 1 P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 S(0.41)T(0.41)VHEILCKLS(0.108)LEGDHS(0.033)T(0.038)PPSAYGSVK 46.66 0.0005214999999999999 4207000.0 6727.3 8299.1 36115.0 69052.0 61507.0 45466.0 20929.0 56632.0 28105.0 44148.0 True False 8866.44146346735 10981.621777254099 35636.09150287821 53133.12824276516 52967.81473810166 42623.00383259934 22791.640455154695 47880.8256738965 29590.572922505322 42602.39195760539 0.2081207428984398 0.2577700751681305 0.8364810017789729 1.2471865029465752 1.2433061221259862 1.0004838196647377 0.5349849951579051 1.1238999378613248 0.6945753879723837 1.0 15.378646813955896 -5.300859336058437 3.7596845406867065 0.9799445519500116 0.21448061930514323 0.6594162037901693 0.21094039714417553 0.13280086972062846 3.9956292656770698 0.05927216099516608 0.14725070792565226 5.001965177409574e-06 5.300859336058437 -0.7654639326448684 (ac)S(ph)VAGGEIR ddPTM_PC-9_AZD4547_30min_R2 1 SVAGGEIR 8 0 Q9H773 Q9H773 DCTPP1 dCTP pyrophosphatase 1 1 S(1)VAGGEIR 76.774 0.0010079000000000002 6373100.0 1170.1 0.0 0.0 784.46 1032.5 0.0 843.92 836.45 0.0 1172.5 True False 1542.1674604080604 0.0 0.0 603.6148667861835 889.1551972473048 0.0 919.0272451103324 707.1958722088351 0.0 1131.451131881225 1.362999617883586 0.0 0.0 0.5334873506932409 0.7858538227532081 0.0 0.8122553588172186 0.6250343936931725 0.0 1.0 10.143958559664505 -11.369490117524382 4.478802458471417 1.1141901626760657 0.44457419294869 0.12016821712352188 0.43888754509984235 0.24398313650124087 0.008355853098155045 0.2071825963384226 0.09946479150634926 4.270806376530282e-12 11.369490117524382 -0.6696159697273758 (ac)S(ph)VAGGEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVAGGEIR 8 0 Q9H773 Q9H773 DCTPP1 dCTP pyrophosphatase 1 1 S(1)VAGGEIR 67.032 0.0010311 5542400.0 617.63 0.0 961.67 893.43 1038.0 915.34 710.13 690.21 1012.0 750.55 True False 722.1825602514512 0.0 984.5998599537845 843.3740136391415 834.6113513453474 867.3379590360223 642.861345504023 672.092718837945 1026.7985854840974 886.618773649469 0.8145356061871201 0.0 1.1105109537676596 0.9512250797123042 0.9413418440373754 0.9782535457329833 0.7250707571393957 0.7580402522625374 1.1581060721933794 1.0 9.79217010085024 -5.277878096149652 24.99943876209071 0.9364848998206567 0.40726774092404117 0.48985962740474553 0.2221921258212931 561.1446553272788 853369.2335058337 0.05488595426196746 0.11477847222514172 5.273778724474597e-06 5.277878096149652 -0.5292171588966156 (ac)S(ph)VAGGEIRGDTGGEDTAAPGR ddPTM_PC-9_AZD4547_30min_R2 2 SVAGGEIRGDTGGEDTAAPGR 21 1 Q9H773 Q9H773 DCTPP1 dCTP pyrophosphatase 1 1 S(0.988)VAGGEIRGDT(0.012)GGEDTAAPGR;S(0.982)VAGGEIRGDT(0.018)GGEDTAAPGR 69.92 0.00010984 25366000.0 0.0 793.21 1249.6 1718.9 0.0 3014.8 0.0 1302.1 1050.5 1609.8 True False 0.0 1049.5996204330263 1233.0294875258637 1322.6341617402688 0.0 2826.2840794114386 0.0 1100.8903642813373 1106.0272853617448 1553.4413919849844 0.0 0.6756609073560541 0.7937405903355652 0.8514219902755452 0.0 1.8193696228217648 0.0 0.708678402649373 0.7119852033480744 1.0 10.60125209735608 -4.7707020781677265 6.324711929430402 0.7159289393028055 7.713374094222794e-17 0.16904399803879055 0.4846105200574246 0.20877422506161616 35.85437101864703 0.11271607187771339 0.6331680153404345 1.6955004986160207e-05 4.7707020781677265 -0.7159289393028054 (ac)S(ph)VAGGEIRGDTGGEDTAAPGR ddPTM_PC-9_Lapatinib_30min_R1 2 SVAGGEIRGDTGGEDTAAPGR 21 1 Q9H773 Q9H773 DCTPP1 dCTP pyrophosphatase 1 1 S(0.992)VAGGEIRGDT(0.008)GGEDTAAPGR;S(1)VAGGEIRGDTGGEDTAAPGR 78.985 1.1594e-12 31305000.0 1148.9 0.0 1054.3 714.44 924.37 2366.06 0.0 0.0 0.0 0.0 True False 1132.5164753175445 0.0 967.6195237156908 766.9823009019746 870.0003739813435 2264.8691293552492 0.0 0.0 0.0 0.0 0.0 (ac)S(ph)YGRPPPDVEGMTSLK ddPTM_PC-9_AZD4547_30min_R2 2 SYGRPPPDVEGMTSLK 16 1 J3QL05;J3KP15;Q01130-2;Q01130 J3QL05 SRSF2 Serine/arginine-rich splicing factor 2 1 S(0.54)Y(0.46)GRPPPDVEGMTSLK;S(0.55)Y(0.45)GRPPPDVEGMTSLK 74.32600000000001 0.0079975 2879000.0 9631.0 10536.2 13963.1 19958.7 14705.1 13049.4 12448.3 15958.2 14173.3 10305.3 True False 12693.457662755336 13941.82060337925 13777.940170672537 15357.530073841113 12663.550693502506 12233.418955111993 13556.17458444752 13492.226872954783 14922.471702634575 9944.51458368919 1.2764280806199342 1.401960898749786 1.385481418396315 1.544321740855029 1.2734206971020012 1.2301675312716642 1.363181125671243 1.356750674898148 1.500573162928449 1.0 13.279685235932673 (ac)S(ph)YGRPPPDVEGMTSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SYGRPPPDVEGMTSLK 16 1 J3QL05;J3KP15;Q01130-2;Q01130 J3QL05 SRSF2 Serine/arginine-rich splicing factor 2 1 S(0.868)Y(0.132)GRPPPDVEGMTSLK 72.29 0.022313999999999997 0.0 19402.0 20533.0 23604.0 23851.0 26409.0 17481.0 23666.0 22823.0 18918.0 14151.0 True False 22686.375393032475 22571.380542130428 24166.808878668493 22514.7057959853 21234.34602859274 16564.265586458274 21424.18515299765 22223.92043296737 19194.639960660235 16716.46428074564 1.357127620531759 1.3502484833547366 1.445689020883699 1.3468581284810444 1.2702653905737045 0.9908952819369421 1.281621806692367 1.329462980910702 1.148247598193896 1.0 14.028982113089551 -6.3934642437967595 3.5271318129211675 1.1755306721389365 1.3787485527879069 0.49619999525916414 0.10452801840277191 0.23732871254448243 5.386248269770378 0.03458482692477675 0.0394614208739946 4.0414364697750996e-07 6.3934642437967595 0.2032178806489704 (ac)S(ph)YGRPPPDVEGMTSLK ddPTM_PC-9_Lapatinib_30min_R1 1 SYGRPPPDVEGMTSLK 16 1 J3QL05;J3KP15;Q01130-2;Q01130 J3QL05 SRSF2 Serine/arginine-rich splicing factor 2 1 S(0.562)Y(0.433)GRPPPDVEGMT(0.003)S(0.001)LK 53.251999999999995 0.035057 3343200.0 15771.0 21555.0 22505.0 19169.0 21807.0 17838.0 19064.0 17084.0 19827.0 16047.0 True False 15546.102647952808 21505.090721835262 20654.725771812235 20578.752205909437 20524.355134211582 17075.110322408953 20051.040639131592 17877.78500820827 17593.87447243403 18820.702568716562 0.8260107501934207 1.1426295401735238 1.097447116886282 1.0934104149818016 1.0905201364972847 0.9072514833102404 1.0653715272276858 0.9498999807756596 0.9348149681552406 1.0 14.200032863805301 -6.745631876513768 24.999387396971603 0.9742053229241507 1.060196724555246 0.1556097160132338 0.08980552187075529 426.1848470636752 674005.2745022401 0.02910231406643278 0.029009388214509407 1.7962555519679558e-07 6.745631876513768 0.0859914016310952 (ac)SASAPAAEGEGT(ph)PTQPASEKEPEMPGPR ddPTM_PC-9_Lapatinib_30min_R1 1 SASAPAAEGEGTPTQPASEKEPEMPGPR 28 1 H0Y8X0;B4DFG0;H0Y993;P35659;D6R9L5;A0A494C198;P35659-2 H0Y8X0 DEK Protein DEK 1 S(0.191)AS(0.174)APAAEGEGT(0.558)PT(0.077)QPASEKEPEMPGPR 54.56 5.847e-13 10374000.0 62929.0 59548.0 54229.0 51858.0 52051.0 55143.0 58919.0 51483.0 52762.0 42337.0 True False 62031.62092023475 59410.1202646182 49770.500949993555 55671.810313216716 48989.462516203326 52784.66243461137 61969.53752711893 53875.08812793173 46819.38795150878 49654.89403949354 1.2492549248196412 1.1964605184207167 1.0023282077776274 1.1211746876136228 0.9865988733605804 1.063030411315117 1.248004627254482 1.0849904963059958 0.9428957378152996 1.0 15.59964829787803 -5.104370783809579 4.885403318078548 1.0664754608681526 1.2379607089113145 0.40073833203134124 0.08174236635668915 0.22164109926840445 8.050631740543803 0.02159082240050072 0.06299471351310461 7.863741272405406e-06 5.104370783809579 0.1714852480431619 (ac)SCINLPT(ph)VLPGSPSKTR ddPTM_PC-9_AZD4547_30min_R2 1 SCINLPTVLPGSPSKTR 17 1 K7ERV3;P04183;K7ENW5;K7ES52;K7ERJ1 K7ERV3 TK1 Thymidine kinase;Thymidine kinase, cytosolic 1 SCINLPT(0.832)VLPGS(0.083)PS(0.033)KT(0.052)R 92.439 5.4405e-05 10058000.0 4543.0 1511.1 6727.9 16384.0 12307.0 6089.5 5549.9 7096.5 3616.1 6571.0 True False 5987.57949972978 1999.5335238289306 6638.683650068235 12606.921930276663 10598.385484283363 5708.72260235371 6043.830348419079 5999.898986347061 3807.2396635855357 6340.951290056742 0.9442714863807445 0.31533652166109566 1.0469538948325257 1.9881751733443531 1.6714188454503207 0.9002943472071089 0.9531425289288092 0.9462143315555055 0.6004208973432228 1.0 12.630483579048 -6.955007966421635 24.99571776200523 0.87849618673977 1.1910324858819814 0.11911931896789352 0.42625666433554754 348.73740305224385 193742.97786711433 0.17302831732527535 0.15259656680000622 1.1091544694519615e-07 6.955007966421635 0.31253629914221137 (ac)SCINLPT(ph)VLPGSPSKTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SCINLPTVLPGSPSKTR 17 1 K7ERV3;P04183;K7ENW5;K7ES52;K7ERJ1 K7ERV3 TK1 Thymidine kinase;Thymidine kinase, cytosolic 1 S(0.002)CINLPT(0.619)VLPGS(0.299)PS(0.069)KT(0.011)R;SCINLPT(0.992)VLPGS(0.002)PS(0.002)KT(0.003)R 140.49 9.424299999999999e-13 16168500.0 27879.6 4162.799999999999 14695.5 47164.0 45292.0 93143.0 39839.0 99632.0 74896.0 46745.0 True False 32599.065632800164 4576.055273013225 15045.896452994102 44521.553987751104 36417.357731342454 88258.41711111956 36065.16151061745 97016.76556882972 75991.21231068873 55219.49846678363 0.5903542505444809 0.08287027952211255 0.27247434096209167 0.8062650915696437 0.6595017836543501 1.598319788511117 0.6531236702975824 1.7569294952432164 1.3761662894566125 1.0 15.7528901642018 -6.314607529604576 1.2105043218705898 1.3029231369656946 0.2864528697005749 0.5788802997718385 0.33965502403388004 0.30966791022624984 0.9342448748661873 0.13693493048959923 0.18923415048929254 4.846101102127861e-07 6.314607529604576 -1.0164702672651198 (ac)SCINLPT(ph)VLPGSPSKTR ddPTM_PC-9_Lapatinib_30min_R1 2 SCINLPTVLPGSPSKTR 17 1 K7ERV3;P04183;K7ENW5;K7ES52;K7ERJ1 K7ERV3 TK1 Thymidine kinase;Thymidine kinase, cytosolic 1 S(0.001)CINLPT(0.378)VLPGS(0.32)PS(0.11)KT(0.191)R;SCINLPT(0.498)VLPGS(0.238)PS(0.238)KT(0.027)R 97.823 3.6849e-05 26934000.0 162622.0 19953.6 33890.0 30195.9 20304.2 24866.5 7233.700000000001 10094.800000000001 32403.0 14917.5 True False 160302.98045877728 19907.39866514553 31103.695019183113 32416.607216569526 19109.946875593087 23803.017761642684 7608.225591234064 10563.841260879235 28753.43292128311 17495.969998680688 9.162280254873847 1.1378276635503308 1.7777633947433915 1.852804229717698 1.092248493626481 1.3604857440563507 0.43485588920235774 0.6037871156429634 1.6434317687702544 1.0 14.094735031180255 -4.761108626184358 24.999999958975387 1.2134856659348938 9.162289135790337 0.9664082154140298 0.44470179940344456 1.3750459275318683 103780.38401304431 0.12064101906878275 0.6854320200179829 1.7333703911368557e-05 4.761108626184358 7.948803469855443 (ac)SCINLPTVLPGS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 4 SCINLPTVLPGSPSK 15 0 K7ERV3;P04183;K7ENW5;K7ES52;K7ERJ1 K7ERV3 TK1 Thymidine kinase;Thymidine kinase, cytosolic 1 SCINLPT(0.001)VLPGS(0.5)PS(0.5)K;SCINLPT(0.004)VLPGS(0.855)PS(0.141)K;SCINLPTVLPGS(0.917)PS(0.083)K;SCINLPTVLPGS(0.805)PS(0.195)K 156.72 1.4118e-17 109161600.0 172447.0 165503.0 194331.0 239411.0 216051.0 208892.0 191533.0 216017.0 192230.0 208353.0 True False 227281.55887957278 218998.6081624375 191754.04396638044 184218.49281307787 186056.0479617219 195829.95021773098 208579.06595141374 182636.53622683484 202390.88535467675 201058.6248877177 1.130424317815261 1.0892276234592695 0.9537220503396288 0.9162426775571338 0.9253820773201146 0.9739942781718182 1.0374042201268205 0.9083745416483835 1.0066262288807708 1.0 17.617256699736224 -5.182372236394784 3.9204078846535415 0.9614478430358413 1.1206158176643657 0.6795806632225717 0.03997330194844799 0.12724721970275144 3.6766858136585054 0.010572634418911238 0.031666338953112556 6.57094396393174e-06 5.182372236394784 0.1591679746285244 (ac)SCINLPTVLPGS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SCINLPTVLPGSPSK 15 0 K7ERV3;P04183;K7ENW5;K7ES52;K7ERJ1 K7ERV3 TK1 Thymidine kinase;Thymidine kinase, cytosolic 1 SCINLPTVLPGS(0.761)PS(0.239)K;SCINLPTVLPGS(0.752)PS(0.248)K;SCINLPT(0.001)VLPGS(0.895)PS(0.104)K;SCINLPTVLPGS(0.681)PS(0.319)K 137.17 2.2934e-09 78449300.0 172754.0 173777.0 171915.0 206222.0 216495.0 180083.0 208879.0 183159.0 160261.0 145158.0 True False 201997.84015297078 191028.43210781657 176014.10559126845 194668.04992074426 174074.35887236145 170639.13046199674 189092.46896699863 178351.27032300207 162604.51394097536 171473.996329904 1.1780085871699228 1.1140373245882202 1.0264769548650956 1.1352628041992823 1.0151647631600917 0.9951312392212459 1.1027471979086432 1.0401068041819395 0.9482750587333115 1.0 17.387630285760196 -1.5228787452803647 0.32270297371411394 1.0070106389203863 2.600526647318234 0.5328788939729128 0.047330667199490924 49.18262945300663 0.7015922161243452 0.04511940250818765 46.3864346585769 0.029999999999998125 1.5228787452803647 1.5935160083978477 (ac)SCINLPTVLPGS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 4 SCINLPTVLPGSPSK 15 0 K7ERV3;P04183;K7ENW5;K7ES52;K7ERJ1 K7ERV3 TK1 Thymidine kinase;Thymidine kinase, cytosolic 1 SCINLPTVLPGS(0.81)PS(0.189)K;SCINLPTVLPGS(0.781)PS(0.219)K;SCINLPTVLPGS(0.802)PS(0.198)K;SCINLPTVLPGS(0.665)PS(0.334)K 142.32 1.9290999999999998e-10 117591800.0 175396.0 195113.0 204706.0 197223.0 199025.0 196082.0 169149.0 170207.0 183831.0 157210.0 True False 172894.8208763131 194661.22783620653 187875.8628680108 211727.43733664157 187318.7407982051 187696.02994946696 177906.70756758662 178115.43859120263 163126.0169537511 184383.5390308424 0.9376911940462997 1.0557408153644614 1.0189405402213494 1.148299020886161 1.0159190011363852 1.017965220409781 0.9648730494202502 0.9660050974583405 0.8847103044619645 1.0 17.492350338346107 -7.24933564399829 1.8057723703506856 0.9441743233716673 1.0414712407928843 0.33130553532095663 0.05521266590910854 0.4020414915913026 2.5597777727251843 0.02921201245172052 0.01834826887225595 5.63202217387968e-08 7.24933564399829 0.09729691742121704 (ac)SCINLPTVLPGS(ph)PSKTR ddPTM_PC-9_AZD4547_30min_R2 3 SCINLPTVLPGSPSKTR 17 1 K7ERV3;P04183;K7ENW5;K7ES52;K7ERJ1 K7ERV3 TK1 Thymidine kinase;Thymidine kinase, cytosolic 1 S(0.002)CINLPT(0.03)VLPGS(0.412)PS(0.412)KT(0.145)R;SCINLPTVLPGS(0.867)PS(0.099)KT(0.034)R;SCINLPT(0.112)VLPGS(0.387)PS(0.385)KT(0.117)R 95.9 4.2479e-05 45844700.0 52782.2 8763.2 46070.2 201721.0 130796.0 55755.3 31640.8 62178.5 29547.0 71961.1 True False 69565.84166203767 11595.73302628395 45459.27904626605 155217.34000838245 112637.23310330107 52268.91227703614 34456.76990364843 52570.24154478695 31108.79409860398 69441.76379225418 1.0017867902974742 0.16698500143191042 0.6546388882382732 2.2352159785678722 1.622038769641175 0.7527013921104699 0.4961966404933378 0.7570407010694457 0.44798392782289875 1.0 16.083515971658194 -6.977418356182722 24.8254796222357 0.6506857247287614 1.123678945496488 0.14939134580030944 0.5321920147252212 475.1580685115291 522370.54616479285 0.21166089844878394 0.18665562882425113 1.053371693796654e-07 6.977418356182722 0.47299322076772654 (ac)SCINLPTVLPGS(ph)PSKTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SCINLPTVLPGSPSKTR 17 1 K7ERV3;P04183;K7ENW5;K7ES52;K7ERJ1 K7ERV3 TK1 Thymidine kinase;Thymidine kinase, cytosolic 1 SCINLPTVLPGS(0.676)PS(0.296)KT(0.028)R 159.64 5.6374e-29 5267400.0 6759.1 2321.6 6541.2 13235.0 12644.0 24226.0 10972.0 24422.0 23344.0 11639.0 True False 7903.282131689815 2552.073105080116 6697.1670156391465 12493.48585844894 10166.498965713452 22955.545912564383 9932.652729599002 23780.948377247936 23685.361837490876 13749.058565726697 0.5748235120178276 0.18561802561826735 0.48710004278646934 0.9086793687527365 0.7394323703774338 1.6696085628573423 0.7224242068732522 1.7296419433784709 1.7226897190279735 1.0 13.747045216437204 -6.274329813936769 0.9227755741405679 1.4192237461846193 0.33441254367601864 0.5723869270431445 0.34333154204221694 0.406248380894721 0.7385935496924104 0.16528136400196297 0.2619780238849319 5.317043165374155e-07 6.274329813936769 -1.0848112025086007 (ac)SCINLPTVLPGS(ph)PSKTR ddPTM_PC-9_Lapatinib_30min_R1 1 SCINLPTVLPGSPSKTR 17 1 K7ERV3;P04183;K7ENW5;K7ES52;K7ERJ1 K7ERV3 TK1 Thymidine kinase;Thymidine kinase, cytosolic 1 SCINLPTVLPGS(0.753)PS(0.227)KT(0.021)R 168.55 4.5987e-40 8932000.0 68054.0 9420.5 14783.0 14556.0 8534.9 11761.0 6235.1 5271.2 14622.0 7169.4 True False 67083.53748042475 9398.687411043793 13567.598804030218 15626.496797392541 8032.893962259019 11258.009446230062 6557.922969421396 5516.1191954616825 12975.116383513923 8408.621237374988 7.977947345546863 1.1177441753789692 1.6135343025946267 1.8583899020133339 0.9553164229296094 1.338865091959428 0.7799046697777834 0.6560075712464497 1.5430729982035092 1.0 13.037653545657129 -4.760954229470969 24.999995536773667 1.2122034274175115 7.977955000966383 0.9689930162485771 0.3633624163445265 1.9014754689959301 97885.45529521252 0.09613094188892081 0.5511895106518659 1.7339867339191406e-05 4.760954229470969 6.765751573548871 (ac)SDAAVDT(ph)SSEITTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDAAVDTSSEITTK 14 0 B8ZZQ6;P06454-2;P06454 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 1 S(0.024)DAAVDT(0.956)S(0.017)S(0.003)EITTK 106.14 0.00098346 18634000.0 18898.0 16469.0 20044.0 24666.0 24702.0 24744.0 17646.0 24501.0 15814.0 14763.0 True False 22097.058147486234 18103.93348017075 20521.924977293296 23284.04398825097 19861.8204247907 23446.38108067752 15974.443134023346 23857.874710955355 16045.2498328513 17439.415036156308 1.2670756502826188 1.0381043998687298 1.176755351870815 1.3351390479541472 1.138904050601017 1.3444476796995344 0.915996499934447 1.3680432893816656 0.9200566532527293 1.0 14.090064028690094 -8.285588784093612 24.91638170463692 0.9600282398559409 1.190091506731163 0.3256403199449627 0.13663076991207704 987.4565613963182 1018807.1974178513 0.12224004246954247 0.03163266834281566 5.1809716505840915e-09 8.285588784093612 0.23006326687522216 (ac)SDAAVDTS(ph)SEITTK ddPTM_PC-9_AZD4547_30min_R2 3 SDAAVDTSSEITTK 14 0 B8ZZQ6;P06454-2;P06454 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 1 SDAAVDT(0.279)S(0.56)S(0.14)EIT(0.009)T(0.011)K;SDAAVDT(0.146)S(0.681)S(0.146)EIT(0.006)T(0.021)K;S(0.018)DAAVDT(0.023)S(0.851)S(0.097)EIT(0.006)T(0.004)K 95.264 6.78e-05 109864400.0 125867.0 113939.0 160400.0 209436.0 172141.0 152521.0 130351.0 176841.0 140342.0 150909.0 True False 165890.08780376104 150767.5535514158 158272.9911965018 161153.76595394444 148242.19351994988 142983.8377590263 141951.98647665262 149514.2868519128 147760.19160612836 145625.72184312448 1.1391537545988364 1.0353085405738305 1.086847771075783 1.1066298172760136 1.017967098419907 0.9818583966440753 0.9747727577245632 1.0267024599746004 1.0146572304397106 1.0 17.15190567542718 -6.372714291429875 4.660616311801464 0.9998354517988793 1.0873236825099102 0.7134388357355939 0.02781643775665374 0.1315878997309968 4.530309126187504 0.008845707581946327 0.010075581302099436 4.239217590195703e-07 6.372714291429875 0.08748823071103085 (ac)SDAAVDTS(ph)SEITTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SDAAVDTSSEITTK 14 0 B8ZZQ6;P06454-2;P06454 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 1 SDAAVDT(0.009)S(0.853)S(0.103)EIT(0.031)T(0.004)K;SDAAVDT(0.249)S(0.619)S(0.129)EIT(0.002)T(0.001)K;SDAAVDT(0.041)S(0.833)S(0.124)EIT(0.002)TK 143.58 1.7338e-10 46220100.0 229365.0 195379.0 250678.0 256327.0 252927.0 209476.0 251983.0 225043.0 201112.0 164504.0 True False 268191.9643347543 214774.93590517243 256655.11422160943 241965.82921334685 203367.77000166103 198490.70979857762 228113.34604106282 219135.85970276865 204052.8825334758 194327.27298705236 1.3801046050423573 1.1052228161483153 1.320736458020022 1.2451460131870864 1.0465220186319963 1.0214248712881524 1.173861715520814 1.1276639471875327 1.0500475789987103 1.0 17.568128865540096 -1.5228787453007038 0.20134358076505932 1.0108187034871803 2.479038903855687 0.5233142413212101 0.08564300653801411 47.888194511297684 0.581022687825091 0.16293902378664268 22.2247221043427 0.029999999998593152 1.5228787453007038 1.4682202003685065 (ac)SDAAVDTS(ph)SEITTK ddPTM_PC-9_Lapatinib_30min_R1 2 SDAAVDTSSEITTK 14 0 B8ZZQ6;P06454-2;P06454 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 1 SDAAVDT(0.007)S(0.79)S(0.199)EIT(0.003)T(0.001)K;SDAAVDT(0.315)S(0.473)S(0.204)EIT(0.004)T(0.004)K 115.1 0.00082777 82103000.0 151116.0 148795.0 160015.0 138957.0 142742.0 122025.0 124461.0 130810.0 144962.0 99281.0 True False 148961.05812871997 148450.47431943784 146859.18437576233 149176.36132696285 134346.1962015696 116806.27520416827 130904.98158765005 136887.91014538272 128634.85304246633 116441.5885663831 1.2792771033332098 1.2748922111690923 1.2612262180882068 1.2811261265292488 1.153764714614651 1.0031319277096367 1.124211574226518 1.1755929460490244 1.1047157173498356 1.0 16.829246901260298 -6.3915834135661225 3.8286601796196362 1.09376955829907 1.2731566044662073 0.760792733259642 0.05055303729714267 0.1265639477095145 3.259644676758711 0.0167103583094625 0.019034742646882288 4.0589769627895877e-07 6.3915834135661225 0.1793870461671372 (ac)SDAAVDTSSEITTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SDAAVDTSSEITTK 14 0 B8ZZQ6;P06454-2;P06454 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 0 ; 108.35 8.5013e-12 3591900.0 34832.0 35029.0 40280.0 43060.0 46691.0 42592.0 44671.0 40522.0 35304.0 35103.0 False True 40728.36963664095 38506.4476214039 41240.427962750684 40647.48780240359 37542.23372414797 40358.40054106918 40439.43948996696 39458.34043660801 35820.25421139386 41466.89602480489 0.9821899766087588 0.9286069446425387 0.9945385817660735 0.9802394608482116 0.9053543265377461 0.9732679416594716 0.975222246337818 0.9515624321869813 0.8638277191031302 1.0 15.339672438917294 -8.017783804017716 24.613214317578556 0.9238409322265833 0.9616803746812992 0.0791015787298116 0.03978776702376141 1215.2539456542602 1681929.1651562392 0.024311794036508856 0.009609799605114782 9.598783493010489e-09 8.017783804017716 0.03783944245471593 (ac)SDAAVDTSSEITTK ddPTM_PC-9_Lapatinib_30min_R1 3 SDAAVDTSSEITTK 14 0 B8ZZQ6;P06454-2;P06454 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 0 ;; 131.83 3.3684e-20 16785200.0 114946.4 106866.8 117132.0 117545.9 116868.8 107155.3 116272.0 99099.0 114849.5 102432.2 False True 113307.24325741206 106619.35649047664 107501.8591025952 126190.61760762717 109994.80695690133 102572.51761020465 122291.99523673457 103703.50131868568 101913.93989114896 120137.46928767319 0.9431465797410306 0.8874779627259588 0.8948237360084422 1.0503851825400077 0.9155745298206265 0.8537928942434382 1.0179338383090317 0.863206973923882 0.8483110264884357 1.0 16.874326653164303 (ac)SDEFS(ph)LADALPEHSPAK ddPTM_PC-9_AZD4547_30min_R2 2 SDEFSLADALPEHSPAK 17 0 Q8NDC0 Q8NDC0 MAPK1IP1L MAPK-interacting and spindle-stabilizing protein-like 1 S(0.434)DEFS(0.566)LADALPEHSPAK;S(0.021)DEFS(0.51)LADALPEHS(0.469)PAK 73.499 2.7249e-05 11194400.0 19616.1 22168.7 25324.3 29473.4 27326.3 23926.0 22456.3 22124.6 22888.4 21665.2 True False 25853.611759773146 29334.29874244353 24988.48323539633 22678.76298949075 23532.514931272646 22429.90343770669 24454.86719638252 18705.7514427301 24098.234096405293 20906.707942373654 1.2366180190126024 1.4031046314560534 1.1952375909336612 1.0847601187141234 1.1255963873478623 1.0728567835515521 1.1697139149687679 0.8947248650667443 1.1526556052166905 1.0 14.351678286568994 -5.5679497507290385 3.0429784964860915 1.0728679854768226 1.31997610442916 0.584322021336364 0.08400360366157683 0.16337295670059956 3.06673509472458 0.022544607101927697 0.04600508989169782 2.704271238904362e-06 5.5679497507290385 0.24710811895233742 (ac)SDEFS(ph)LADALPEHSPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SDEFSLADALPEHSPAK 17 0 Q8NDC0 Q8NDC0 MAPK1IP1L MAPK-interacting and spindle-stabilizing protein-like 1 S(0.07)DEFS(0.775)LADALPEHS(0.155)PAK;S(0.181)DEFS(0.762)LADALPEHS(0.057)PAK;S(0.159)DEFS(0.84)LADALPEHS(0.001)PAK;S(0.283)DEFS(0.66)LADALPEHS(0.056)PAK;S(0.401)DEFS(0.591)LADALPEHS(0.008)PAK;SDEFS(1)LADALPEHSPAK 146.16 1.3426999999999998e-81 21505000.0 50594.50000000001 48555.399999999994 40013.18 59986.4 58917.799999999996 51209.9 63033.9 55283.3 50143.100000000006 44242.3 True False 59159.14956307504 53375.659220540576 40967.24596203017 56625.55648653276 47373.28003496615 48524.36269412329 57062.87266608375 53832.17195249818 50876.34797607474 52263.078768145926 1.1319491877912908 1.0212880771400854 0.7838659131386552 1.0834715026594595 0.9064387546919627 0.9284635317676431 1.091839095802815 1.0300229764747157 0.9734663394358545 1.0 15.673504494500241 -7.245916168648473 24.733476841569715 1.0263340266589627 0.9709770557755333 0.05608199254191515 0.09480210922211736 2107.4511712433587 3357853.086526807 0.03668440308890717 0.028288087283588302 5.6765416844829774e-08 7.245916168648473 -0.05535697088342939 (ac)SDEFS(ph)LADALPEHSPAK ddPTM_PC-9_Lapatinib_30min_R1 2 SDEFSLADALPEHSPAK 17 0 Q8NDC0 Q8NDC0 MAPK1IP1L MAPK-interacting and spindle-stabilizing protein-like 1 S(0.097)DEFS(0.903)LADALPEHSPAK;S(0.426)DEFS(0.574)LADALPEHSPAK 90.65299999999999 5.385e-05 2342600.0 15034.8 14649.7 14395.0 13368.7 15449.3 14623.0 12880.1 13540.400000000001 16309.3 13250.3 True False 14820.400994955364 14615.779519724882 13211.498666306912 14351.878794675857 14540.60254849245 13997.608377877905 13546.968555186679 14169.536415660445 14472.374889457229 15540.596700085056 0.9536571394890037 0.9404902399690281 0.8501281463815739 0.9235088633757098 0.9356527827797544 0.9007124145883854 0.8717148264398711 0.9117755700836695 0.931262497107207 1.0 13.923754278386873 -8.707382346565261 2.5336625722991135 0.9999394037467443 0.9096657605473939 0.44675067530942336 0.02970974827769319 0.7472302467769538 8.355248401701918 0.0296887264318494 0.008007630288982938 1.961632523570104e-09 8.707382346565261 -0.09027364319935038 (ac)SDEFSLADALPEHS(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 6 SDEFSLADALPEHSPAK 17 0 Q8NDC0 Q8NDC0 MAPK1IP1L MAPK-interacting and spindle-stabilizing protein-like 1 SDEFSLADALPEHS(1)PAK;SDEFSLADALPEHS(1)PAK;SDEFS(0.006)LADALPEHS(0.993)PAK;S(0.253)DEFS(0.253)LADALPEHS(0.493)PAK;SDEFS(0.001)LADALPEHS(0.999)PAK;S(0.003)DEFS(0.019)LADALPEHS(0.977)PAK 91.62200000000001 2.1764000000000003e-22 95849900.0 124050.9 117660.3 134385.4 175134.0 168884.0 161514.0 136467.2 131203.4 130544.5 149147.8 True False 163496.5057809879 155691.69100242807 132603.36179013964 134759.56209332705 145437.3717500378 151414.5040473863 148612.5164280032 110928.92928419453 137444.81575812114 143926.18091905746 1.1359747388346015 1.0817468372205847 0.921328982283733 0.9363102753981528 1.0104997632906707 1.0520289156601756 1.0325606882571372 0.7707348904545711 0.9549674345588217 1.0 17.13496952410018 -7.704764502327658 24.999990694579065 0.8971360304206097 1.0197411864858907 0.2975106835290482 0.08074383286979575 96.62412597978273 42621.73081115948 0.03911981402025629 0.02258581342519956 1.9734925791452806e-08 7.704764502327658 0.122605156065281 (ac)SDEFSLADALPEHS(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 SDEFSLADALPEHSPAK 17 0 Q8NDC0 Q8NDC0 MAPK1IP1L MAPK-interacting and spindle-stabilizing protein-like 1 S(0.383)DEFS(0.044)LADALPEHS(0.573)PAK;SDEFSLADALPEHS(1)PAK;S(0.204)DEFS(0.121)LADALPEHS(0.676)PAK;S(0.074)DEFS(0.327)LADALPEHS(0.599)PAK;S(0.008)DEFS(0.048)LADALPEHS(0.944)PAK;S(0.002)DEFS(0.016)LADALPEHS(0.983)PAK;S(0.07)DEFS(0.319)LADALPEHS(0.611)PAK;SDEFS(0.001)LADALPEHS(0.999)PAK 115.0 2.3182999999999996e-69 159521200.0 278241.0 273906.0 274834.0 358482.7 343849.4 322407.30000000005 353214.4 341569.9 303981.9 258572.3 True False 325341.7057897514 301097.5774983087 281387.0848737488 338398.07653559453 276474.5784135715 305499.69362238585 319755.3749811962 332604.0520482245 308427.0602102449 305449.41113279935 1.0651246783654904 0.9857526861212423 0.9212232029853579 1.1078694677478693 0.9051403222164651 1.0001646180603199 1.0468357879471475 1.088900616356465 1.0097484197674587 1.0 18.220573933527064 -7.234248881046032 6.625097405347206 1.043830053219997 0.9942033544069379 0.08394918242805727 0.06035559617103135 0.39864725650439625 66.77447949002338 0.022942688864068774 0.017290129785804978 5.831108452983993e-08 7.234248881046032 -0.049626698813059034 (ac)SDEFSLADALPEHS(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 8 SDEFSLADALPEHSPAK 17 0 Q8NDC0 Q8NDC0 MAPK1IP1L MAPK-interacting and spindle-stabilizing protein-like 1 SDEFS(0.002)LADALPEHS(0.998)PAK;S(0.002)DEFS(0.381)LADALPEHS(0.617)PAK;SDEFS(0.003)LADALPEHS(0.996)PAK;S(0.006)DEFS(0.006)LADALPEHS(0.989)PAK;SDEFS(0.007)LADALPEHS(0.993)PAK;S(0.132)DEFS(0.109)LADALPEHS(0.758)PAK;S(0.015)DEFS(0.013)LADALPEHS(0.971)PAK;SDEFSLADALPEHS(1)PAK 95.954 5.110699999999999e-96 49419600.0 218768.1 203693.8 216361.8 206916.5 222078.2 201264.8 181423.8 174641.2 204311.2 185105.09999999998 True False 215648.42677684393 203222.15952100992 198573.3679847008 222133.82966320953 209015.9968985399 192657.17367516417 190817.0366505288 182755.66771104577 181299.5211636841 217100.26989795794 0.9933125687877016 0.9360751122812005 0.9146620042344249 1.0231854145903065 0.9627624921736954 0.8874110279352366 0.8789350503351154 0.8418030424234161 0.8350957889131092 1.0 17.728001993942165 -6.785140859618829 4.880805224142857 0.877087203245553 0.9650737871610936 0.35888739263382474 0.05068653493680736 0.1926132044838341 11.485962800058498 0.017550680993766218 0.016056468434984192 1.6400577485312242e-07 6.785140859618829 0.0879865839155406 (ac)SDEFSLADALPEHSPAK ddPTM_PC-9_Lapatinib_30min_R1 2 SDEFSLADALPEHSPAK 17 0 Q8NDC0 Q8NDC0 MAPK1IP1L MAPK-interacting and spindle-stabilizing protein-like 0 ; 102.66 1.0185e-52 0.0 20756.0 19312.7 20824.8 20225.7 24062.0 22096.0 21455.0 15931.900000000001 23249.0 15928.5 False True 20460.015633815776 19267.982629718743 19112.66533005266 21713.16544895731 22646.720467712155 21151.005588291744 22565.834919878762 16672.154236260427 20630.45279717651 18681.720001607886 1.0951890742423522 1.0313816194686785 1.02306775438277 1.162268005680875 1.2122395831734452 1.1321765654592475 1.2079099203893742 0.8924314375135426 1.1043122793512001 1.0 14.189339667763788 -7.7557929949562 24.999996315698276 0.9987788952535853 1.1213011875143115 0.35770487659951766 0.07644162308824433 159.55672031069577 706463.5447357147 0.03910529849742353 0.02177636862512783 1.754716682509877e-08 7.7557929949562 0.1225222922607262 (ac)SDEREVAEAATGEDAS(ph)SPPPKTEAASDPQHPAASEGAAAAAASPPLLR ddPTM_PC-9_Lapatinib_30min_R1 1 SDEREVAEAATGEDASSPPPKTEAASDPQHPAASEGAAAAAASPPLLR 48 2 K7ERT7;Q99536-3;Q99536 K7ERT7 VAT1 Synaptic vesicle membrane protein VAT-1 homolog 1 S(0.011)DEREVAEAAT(0.032)GEDAS(0.308)S(0.308)PPPKT(0.308)EAAS(0.032)DPQHPAASEGAAAAAASPPLLR 45.269 0.00031889 4958000.0 620.45 1412.8 1257.3 1210.4 1590.8 1136.7 2863.8 1213.3 1296.4 609.0 True False 611.6022692234054 1409.5287484021735 1153.9296473183513 1299.416853776033 1497.2322716331344 1088.0859907771194 3012.0735513189816 1269.6743473694146 1150.385780302793 714.2648385585081 0.8562682022227345 1.9733979223264169 1.6155487223018727 1.8192367643330278 2.096186443469302 1.5233649089783525 4.217026218731123 1.7775960383711522 1.610587163473483 1.0 9.480315292644326 -4.47854002709024 0.783693109664063 2.1352146920887294 1.3384281235557457e-11 0.11299346005094446 0.8217964584943604 8.592879103893846 2.9175684726488145 0.31527673907195625 17.889776900693604 3.3224616207278236e-05 4.47854002709024 -2.135214692075345 (ac)SDLQAAEGPGSWS(ph)PTAR ddPTM_PC-9_AZD4547_30min_R2 1 SDLQAAEGPGSWSPTAR 17 0 Q6PL24 Q6PL24 TMED8 Protein TMED8 1 SDLQAAEGPGS(0.117)WS(0.558)PT(0.326)AR 73.735 0.0046307 0.0 6465.9 4711.1 7331.5 9267.3 8242.6 8021.9 4386.2 7403.4 7006.6 4921.3 True False 8521.921700925115 6233.870944418286 7234.279519683002 7130.867163357718 7098.257267632575 7520.289324874167 4776.563302804696 6259.374643207475 7376.954571742595 4749.006784927141 1.7944639978137782 1.3126683592459694 1.523324738689332 1.5015491630777107 1.4946824860646049 1.5835499222159024 1.0058025854932482 1.3180386819143082 1.5533678737112548 1.0 12.213410102044639 -7.23475729835504 24.951425509095298 1.2458054550319784 1.5210427785964424 0.4082644662780407 0.1846619381596318 819.6224190211062 766460.8864548524 0.06873536726091689 0.0532264347569822 5.824286119389992e-08 7.23475729835504 0.27523732356446406 (ac)SDLQAAEGPGSWS(ph)PTAR ddPTM_PC-9_Lapatinib_30min_R1 2 SDLQAAEGPGSWSPTAR 17 0 Q6PL24 Q6PL24 TMED8 Protein TMED8 1 SDLQAAEGPGS(0.027)WS(0.734)PT(0.24)AR;S(0.001)DLQAAEGPGS(0.27)WS(0.626)PT(0.103)AR 77.795 7.7284e-06 1672500.0 8681.7 7861.5 9396.400000000001 7331.3 9283.2 11349.4 9653.2 9871.7 11151.4 8633.099999999999 True False 8557.897365971208 7843.297179759122 8623.864263152922 7870.4682584998645 8737.180427473422 10864.012618743598 10152.995462529647 10330.375220412636 9895.411902552114 10125.319832117328 0.845197732799088 0.7746221659962116 0.8517127761039394 0.777305644561951 0.8629041425199476 1.072955007730536 1.002733309255529 1.0202517443098318 0.977293761246341 1.0 13.305679859193328 -6.629007393750434 5.0665524987462245 1.0143958865071487 0.8132427227086958 0.8970132716537484 0.03287861514205512 0.05842158991473363 2.3872270780225335 0.010457752176756761 0.010431999648184306 2.3495928193020504e-07 6.629007393750434 -0.20115316379845294 (ac)SDQDHS(ph)MDEMTAVVK ddPTM_PC-9_Lapatinib_30min_R1 1 SDQDHSMDEMTAVVK 15 0 P08047;H3BUU5;P08047-3 P08047 SP1 Transcription factor Sp1 1 S(0.421)DQDHS(0.578)MDEMT(0.001)AVVK 66.24600000000001 0.012407 4026100.0 12461.0 10096.0 13680.0 9888.8 8878.1 10310.0 6960.6 10222.0 12571.0 7043.6 True False 12283.303854932474 10072.623332296394 12555.2832063271 10616.055340069766 8355.90761301618 9869.065333783856 7320.9858095226255 10696.951437245665 11155.121601501405 8261.076874992956 1.4868889420597418 1.2192869627913956 1.5198119320657946 1.2850691865857766 1.0114792223166795 1.194646349758399 0.8862023583975991 1.294861626288254 1.350322938558893 1.0 13.012114141482046 -6.022394104330411 7.5313755227609365 1.130696878659347 1.3921803511453799 0.4241693070809638 0.15017429412294026 0.1992526462780979 52.18701294726177 0.04392802333206682 0.05923800582849683 9.49742550296821e-07 6.022394104330411 0.2614834724860329 (ac)SDQEAKPS(ph)TEDLGDKKEGEYIK ddPTM_PC-9_Lapatinib_30min_R1 1 SDQEAKPSTEDLGDKKEGEYIK 22 3 B8ZZJ0;B9A032;B8ZZN6;P63165 B8ZZJ0 SUMO1 Small ubiquitin-related modifier 1 1 S(0.267)DQEAKPS(0.367)T(0.367)EDLGDKKEGEYIK 45.369 0.006525100000000001 16924000.0 300490.0 95298.0 109400.0 110220.0 82979.0 92286.0 56487.0 67674.0 115120.0 68468.0 True False 296204.9574968836 95077.34333609158 100405.55429621214 118325.94648314174 78098.33836299078 88339.14290917323 59411.620466986256 70818.38109608337 102153.97333265789 80302.60257212487 3.688609683986806 1.1839883178219108 1.2503399775372352 1.4735007670126965 0.9725505259041348 1.1000782051843243 0.7398467616740678 0.881893971399954 1.272112858869137 1.0 16.293159125163186 -4.760725171420099 5.8275509807527985 1.0883022380464589 3.7957084082969237 0.9389058019652889 0.1984526514285936 0.033474399058468635 4.086808790787668 0.054176522358533166 0.3633911080940007 1.7349015242259328e-05 4.760725171420099 2.707406170250465 up (ac)SDS(ph)GEQNYGERES(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 SDSGEQNYGERESR 14 1 P62995 P62995 TRA2B Transformer-2 protein homolog beta 2 S(0.375)DS(0.622)GEQNY(0.003)GERES(1)R 67.416 0.0015526 0.0 0.0 0.0 578.03 531.77 356.81 0.0 401.06 0.0 537.38 0.0 True False 0.0 0.0 570.3649445219075 409.1786422646008 307.27309048892096 0.0 436.753563043831 0.0 565.7848097169863 0.0 0.0 (ac)SDSGEQNYGERES(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 SDSGEQNYGERESR 14 1 P62995 P62995 TRA2B Transformer-2 protein homolog beta 1 SDSGEQNYGERES(1)R;SDSGEQNYGERES(1)R 124.51 9.229799999999999e-16 245070000.0 0.0 0.0 0.0 0.0 0.0 427.59 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 400.85272970529957 0.0 0.0 0.0 0.0 0.0 (ac)SDSGEQNYGERES(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SDSGEQNYGERESR 14 1 P62995 P62995 TRA2B Transformer-2 protein homolog beta 1 SDSGEQNYGERES(1)R;SDSGEQNYGERES(1)R;SDSGEQNYGERES(1)R 106.58 7.5867e-08 308049000.0 0.0 2036.1 973.7 394.91 888.58 644.93 485.38 805.59 435.72 564.1 True False 0.0 2238.2305518838816 996.9167007778136 372.78447301549477 714.4691277249019 611.1087354656217 439.40129255311416 784.4441160931601 442.0915806987457 666.3668645868574 0.0 3.3588563159897937 1.496047828542457 0.5594282861687884 1.0721858569121192 0.9170755149185047 0.659398472379835 1.1771955626567803 0.6634357201612047 1.0 9.3801728535563 -5.548340435140151 9.391977371502575 0.8846144013103151 1.8652883454814373 0.15908985950613141 0.7778661774344657 0.37913227692107 131.61270847641543 0.19584019303577713 0.34258784633432565 2.82917339142774e-06 5.548340435140151 0.9806739441711222 (ac)SDSGEQNYGERES(ph)R ddPTM_PC-9_Lapatinib_30min_R1 4 SDSGEQNYGERESR 14 1 P62995 P62995 TRA2B Transformer-2 protein homolog beta 1 SDSGEQNYGERES(1)R;SDSGEQNYGERES(0.999)R;SDSGEQNYGERES(1)R;SDSGEQNYGERES(1)R 117.07 2.8176e-15 254184000.0 0.0 0.0 1174.8 0.0 495.57 0.0 1392.1 0.0 0.0 726.16 True False 0.0 0.0 1078.212478859143 0.0 466.4215469281069 0.0 1464.1761264023867 0.0 0.0 851.6757884526211 0.0 0.0 1.2659893512038287 0.0 0.5476515280251554 0.0 1.7191707763145354 0.0 0.0 1.0 9.734160527023459 -14.522878745279712 0.08227692128510192 2.330765016224641 9.571953794692971e-09 0.0721578092313444 0.5940626730179672 826.8905670535949 4.779481182261353 217.32660928237098 18.890809527061908 3.0000000000043204e-15 14.522878745279712 -2.3307650066526873 (ac)SDVEENNFEGRES(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 SDVEENNFEGRESR 14 1 Q13595 Q13595 TRA2A Transformer-2 protein homolog alpha 1 SDVEENNFEGRES(1)R 80.37100000000001 4.2935e-05 0.0 2724.5 1334.9 2448.0 4098.4 2540.5 2611.9 1325.0 1146.3 3141.2 3361.8 True False 3590.8343268795497 1766.3803196077283 2415.5379205052136 3153.577199648795 2187.7954272220613 2448.577480103072 1442.9224331348826 969.1656743535029 3307.2374191130993 3244.104405252282 1.1068800131912844 0.5444893563684068 0.7445931507612394 0.9720948544513792 0.674391189038173 0.7547776440668084 0.4447829825694749 0.2987467582067953 1.0194608452670646 1.0 11.66360453532575 -6.636629258697162 2.4962767586308856 0.6385662448039335 0.8123649141944652 0.03272032074299669 0.25194332037453976 0.7617623153590029 9.657939038034549 0.0907599158586525 0.09058265313952084 2.3087172151119163e-07 6.636629258697162 0.17379866939053168 (ac)SDVEENNFEGRES(ph)R ddPTM_PC-9_Lapatinib_30min_R1 2 SDVEENNFEGRESR 14 1 Q13595 Q13595 TRA2A Transformer-2 protein homolog alpha 1 SDVEENNFEGRES(1)R;SDVEENNFEGRES(1)R 107.93 0.00013393 7239600.0 5547.2 3387.63 3223.8 1753.79 2675.05 3167.77 2491.3999999999996 1976.33 4822.3 1636.4 True False 5468.09591076811 3379.7861508703677 2958.7516082278703 1882.7695670719352 2517.7088183506526 3032.291861532538 2620.392501486177 2068.1575067473805 4279.1617929297745 1919.2495596340596 2.8490801956003593 1.7609935789250808 1.541619011126417 0.98099257473891 1.3118194065552895 1.5799362028306003 1.365321403010145 1.077586547495008 2.2296015499650164 1.0 10.906326601738677 -4.674689855605852 1.8519293117103623 1.375068692135012 3.6212978304590715 0.6223140604830053 0.3438994301827963 0.7347380752063561 2.1018719624886195 0.08973052011251555 3.155532017766624 2.114998892974318e-05 4.674689855605852 2.2462291383240593 (ac)SEGES(ph)QTVLSSGSDPK ddPTM_PC-9_AZD4547_30min_R2 1 SEGESQTVLSSGSDPK 16 0 F8W6G1;Q9UHY1;C9JDW7;C9JHZ6 F8W6G1 NRBP1 Nuclear receptor-binding protein 1 S(0.439)EGES(0.561)QTVLSSGSDPK 106.52 1.2734000000000003e-07 7192000.0 30840.0 30718.0 35809.0 44863.0 42707.0 41742.0 37154.0 40952.0 41055.0 37500.0 True False 40646.47848815021 40646.992776769956 35334.149262815044 34520.52847644056 36777.87022648002 39131.866141300365 40460.63402316485 34623.80938334177 43225.08348455632 36187.13641411167 1.1232300346456692 1.12324424656379 0.9764284429269182 0.9539447410649162 1.0163244144440782 1.0813750414923784 1.1180943847048 0.9567988189814252 1.1944875380551003 1.0 15.143189327419734 -6.769411227195702 24.89174655614823 1.0704475361288228 1.0351740589510616 0.037863351282691804 0.07846605294451105 672.8236755245271 2100853.5352693545 0.028116599114797497 0.02525385896654426 1.7005475218266601e-07 6.769411227195702 -0.03527347717776119 (ac)SEKS(ph)VEAAAELSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEKSVEAAAELSAK 14 1 P20962;F5H7R9;F5GXR3 P20962 PTMS Parathymosin 1 S(0.268)EKS(0.732)VEAAAELSAK 58.831 0.018013 0.0 3262.3 1264.4 3814.5 3382.1 3176.1 4109.3 3505.3 2827.6 3002.4 2098.0 True False 3814.5429566379707 1389.9212758715098 3905.45214657181 3192.611901916142 2553.7660048246203 3893.80107399079 3173.252607825685 2753.3784960898474 3046.3044200172453 2478.3507922411386 1.53914569663826 0.5608250777988628 1.575827021258828 1.2882001659777578 1.0304295956890286 1.5711258818489044 1.2803888044259288 1.110972064450975 1.2291659556646193 1.0 11.275164689416066 -8.926536639037485 1.1364483450914258 1.0014089875966183 1.242795547437854 0.06102751623456182 0.2892210064187407 4.72726568349524 9.493278917828745 0.2673381028701222 0.08254158800419113 1.1843044495279329e-09 8.926536639037485 0.2413865598412357 (ac)SET(ph)APAAPAAAPPAEK ddPTM_PC-9_AZD4547_30min_R2 1 SETAPAAPAAAPPAEK 16 0 P16403 P16403 HIST1H1C Histone H1.2 1 S(0.254)ET(0.746)APAAPAAAPPAEK 42.468999999999994 0.0042526000000000005 8034400.0 42269.0 63226.0 55404.0 66603.0 55048.0 61181.0 68511.0 71316.0 59261.0 53878.0 True False 55709.66275018227 83662.56804818213 54669.306759669525 51248.70735609229 47405.53539764611 57355.34239832534 74608.34627660691 60295.75087864817 62393.41547627065 51991.74761918688 1.0715097164693759 1.6091509110439586 1.0514996949149393 0.9857084961148646 0.9117896121682149 1.1031624252837982 1.435003624480468 1.1597177175170932 1.200063824229774 1.0 15.66599502946304 -1.525049084140762 0.012846230017718485 4.290670223949415e-06 2.5201061734886516 0.03422855332098362 0.2011285187864113 38249.38548528164 38.105369602330086 3087.6234683702255 4512.484767743583 0.029850452288142548 1.525049084140762 2.5201018828184276 (ac)SET(ph)APAAPAAPAPAEKT(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 1 SETAPAAPAAPAPAEKTPVK 20 1 P10412 P10412 HIST1H1E Histone H1.4 2 S(0.43)ET(0.584)APAAPAAPAPAEKT(0.986)PVK 90.084 0.00054498 3642400.0 17162.0 28948.0 27619.0 26307.0 21804.0 19115.0 20292.0 21594.0 18943.0 21348.0 True False 16917.266732874657 28880.972684559827 25348.272432423102 28241.70453757941 20521.531588313344 18297.496009241353 21342.62047048146 22597.33607277272 16809.439861366714 25037.973355578044 0.67566437956552 1.1534868367501327 1.012393138711282 1.1279548922152531 0.8196163202538711 0.7307898187041155 0.852410064000914 0.9025225704914495 0.6713578460463475 1.0 14.611830170726309 -6.290908610084168 23.277392220667892 0.8207905429666876 1.0053126796144687 0.22470740472606965 0.14694979590507795 395.7973557049395 312634.0644405464 0.043793758428437905 0.04966907571902804 5.117895216435647e-07 6.290908610084168 0.18452213664778105 (ac)SETAPAAPAAPAPAEKT(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 7 SETAPAAPAAPAPAEKTPVK 20 1 P10412 P10412 HIST1H1E Histone H1.4 1 S(0.001)ET(0.001)APAAPAAPAPAEKT(0.998)PVK;S(0.071)ET(0.071)APAAPAAPAPAEKT(0.858)PVK;S(0.002)ET(0.002)APAAPAAPAPAEKT(0.995)PVK;S(0.026)ET(0.026)APAAPAAPAPAEKT(0.947)PVK;S(0.119)ET(0.119)APAAPAAPAPAEKT(0.762)PVK;S(0.202)ET(0.202)APAAPAAPAPAEKT(0.596)PVK;S(0.262)ET(0.262)APAAPAAPAPAEKT(0.475)PVK 95.227 1.617e-08 1310760600.0 278096.0 383382.0 345138.0 376846.0 376486.0 385779.0 452837.0 364610.0 370542.0 414747.0 True False 366524.74324385915 507302.73405637173 340561.24461083725 289969.9769126608 324217.4175214025 361656.1781449075 493138.6157384907 308267.9024042843 390128.09364351444 400226.8337691616 0.9157925264332957 1.267538034066372 0.850920567728006 0.7245140816317841 0.8100841576964353 0.9036280119925681 1.232147807517868 0.770232968892045 0.9747674586670223 1.0 18.610458372434806 -5.289094931870315 24.845554477383573 0.9014104268686652 1.0916653894312076 0.1785796703025494 0.15676266512362882 975.7404008169491 876596.8285259863 0.04174223555581613 0.08692583970086946 5.139312997239038e-06 5.289094931870315 0.19025496256254237 (ac)SETAPAAPAAPAPAEKT(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SETAPAAPAAPAPAEKTPVK 20 1 P10412 P10412 HIST1H1E Histone H1.4 1 S(0.192)ET(0.192)APAAPAAPAPAEKT(0.615)PVK;S(0.314)ET(0.314)APAAPAAPAPAEKT(0.372)PVK;S(0.005)ET(0.005)APAAPAAPAPAEKT(0.989)PVK;S(0.168)ET(0.168)APAAPAAPAPAEKT(0.665)PVK 64.203 7.5392e-05 933069200.0 189249.0 169945.0 191550.0 225618.0 401454.0 218126.0 273521.0 288418.0 214962.0 167935.0 True False 221285.1178618703 186816.01647262255 196117.2784574201 212977.35492342475 322791.9705616518 206687.08857112264 247611.11075944675 280847.33310413174 218105.4125818508 198380.2861272716 1.1154592131191101 0.9417065582452585 0.9885925778512101 1.0735812468119355 1.6271373373993596 1.041873124623491 1.2481638956836212 1.4157018249482367 1.0994308801527006 1.0 17.59790914068816 -6.019174860701258 24.907804693260985 1.2592444852187805 1.0117628881360101 0.24879367250981566 0.17780408028068806 875.432789140073 1137171.9222363764 0.0498309439682711 0.06539890099700399 9.56808752248253e-07 6.019174860701258 -0.2474815970827704 (ac)SETAPAAPAAPAPAEKT(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 5 SETAPAAPAAPAPAEKTPVK 20 1 P10412 P10412 HIST1H1E Histone H1.4 1 SETAPAAPAAPAPAEKT(1)PVK;SETAPAAPAAPAPAEKT(1)PVK;S(0.263)ET(0.263)APAAPAAPAPAEKT(0.474)PVK;S(0.006)ET(0.006)APAAPAAPAPAEKT(0.987)PVK;S(0.027)ET(0.027)APAAPAAPAPAEKT(0.946)PVK 107.09 2.5624e-09 69912800.0 114460.6 330229.0 158211.8 184825.0 145051.3 120042.1 140823.5 143766.2 134778.0 142865.0 True False 112828.37085449648 329464.37503971 145204.23651920902 198417.6470581261 136519.66771582793 114908.17921480247 148114.65177532253 150446.10249631616 119597.88236474076 167559.02489435367 0.6733649287207001 1.9662586079588253 0.8665855904255865 1.1841656824108928 0.8147556826730394 0.6857773210798542 0.8839550831040532 0.8978692886949704 0.7137656860926916 1.0 17.354309868049818 -5.915720984462874 1.6436111225779801 0.825752552398398 1.285690064644742 0.19066680058185526 0.32698935876965757 0.5121706348163646 2.8126691986968377 0.10155726305076865 0.18606377758122136 1.2141686511130777e-06 5.915720984462874 0.45993751224634405 (ac)SETAPAAPAAPAPAEKT(ph)PVKK ddPTM_PC-9_AZD4547_30min_R2 4 SETAPAAPAAPAPAEKTPVKK 21 2 P10412 P10412 HIST1H1E Histone H1.4 1 SETAPAAPAAPAPAEKT(1)PVKK;SETAPAAPAAPAPAEKT(1)PVKK;S(0.006)ET(0.006)APAAPAAPAPAEKT(0.988)PVKK;SETAPAAPAAPAPAEKT(1)PVKK 60.99100000000001 0.00046401 1058455000.0 348819.0 398681.0 418274.0 479178.0 468404.0 461070.0 487709.0 421004.0 404902.0 485505.0 True False 459736.18611407594 527546.8366181207 412727.4134646234 368710.91532630025 403374.1898415749 432239.2200126821 531114.1561824764 355947.50550948374 426304.2930961839 468507.6177262206 0.981277931712798 1.1260154940029183 0.8809406674488841 0.7869902246536405 0.860976800759924 0.9225873895294218 1.1336297129171566 0.7597475303325526 0.909919661851264 1.0 18.83771298009394 -5.274240007729128 24.228462220010854 0.9010109792812948 1.0536467140677765 0.23738457835271543 0.104829073592021 624.0678292807082 1181210.1521610394 0.027992310009186783 0.05894489220511256 5.318142771462812e-06 5.274240007729128 0.15263573478648174 (ac)SETAPAAPAAPAPAEKT(ph)PVKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SETAPAAPAAPAPAEKTPVKK 21 2 P10412 P10412 HIST1H1E Histone H1.4 1 S(0.001)ET(0.001)APAAPAAPAPAEKT(0.998)PVKK;SETAPAAPAAPAPAEKT(1)PVKK;SETAPAAPAAPAPAEKT(1)PVKK;SETAPAAPAAPAPAEKT(1)PVKK 67.194 0.00040839 885729000.0 191408.0 187742.0 217703.0 270311.0 477335.0 262012.0 358729.0 421159.0 275260.0 180921.0 True False 223809.5939196765 206379.78501634666 222893.86516322545 255166.35103008666 383804.6333279676 248271.62947423515 324747.5921469493 410104.02250484715 279285.1567592414 213720.54513015185 1.0472067333694128 0.965652529524783 1.042922031793842 1.1939252301396437 1.7958246975939431 1.1616647773523239 1.5194963682559581 1.9188797326672613 1.3067772992491757 1.0 17.70536607655088 -6.032171176957663 6.030054155700209 1.487550417628871 1.0275933622788678 0.3613107969962692 0.2576067055790621 0.1838127099132752 20.733615390562857 0.07363610307933365 0.09913230002697357 9.286003072826386e-07 6.032171176957663 -0.4599570553500032 (ac)SETAPAAPAAPAPAEKT(ph)PVKK ddPTM_PC-9_Lapatinib_30min_R1 4 SETAPAAPAAPAPAEKTPVKK 21 2 P10412 P10412 HIST1H1E Histone H1.4 1 SETAPAAPAAPAPAEKT(1)PVKK;S(0.005)ET(0.005)APAAPAAPAPAEKT(0.989)PVKK;SETAPAAPAAPAPAEKT(1)PVKK;SETAPAAPAAPAPAEKT(1)PVKK 67.88 3.5023e-05 843347000.0 315789.0 311594.0 325163.0 290382.0 247024.0 277225.0 281284.0 263407.0 260810.0 249699.0 True False 311285.7909513902 310872.5232372785 298429.3533054772 311737.66096595506 232494.53398787 265368.73299303895 295847.5091868174 275645.8508345297 231434.83134894428 292859.13944699615 1.0629198444658035 1.0615086960382965 1.0190201127716185 1.0644628047279217 0.7938783622286393 0.9061309593893258 1.0102041197876364 0.941223317650355 0.7902598900821776 1.0 18.15984739271594 -6.230134025536049 24.96053542884509 0.9091324052359359 1.050304541334274 0.5103750036891836 0.06956240043459119 582.8683056824206 464735.2972438711 0.02086130215509723 0.02692903163516636 5.886619631777597e-07 6.230134025536049 0.14117213609833812 (ac)SETAPAAPAAPAPAEKT(ph)PVKKK ddPTM_PC-9_Lapatinib_30min_R1 1 SETAPAAPAAPAPAEKTPVKKK 22 3 P10412 P10412 HIST1H1E Histone H1.4 1 SETAPAAPAAPAPAEKT(1)PVKKK 50.391999999999996 5.373e-05 39812000.0 90766.0 20550.0 25406.0 24559.0 11947.0 17273.0 10323.0 7821.1 23415.0 11319.0 True False 89471.66019555395 20502.417737588225 23317.21674999607 26365.150786422346 11244.300948705713 16534.274055329628 10857.47442917308 8184.4968583292975 20777.756129119036 13275.474068380545 6.739620727267065 1.5443830956229863 1.7564131141299801 1.9860044658758156 0.8469980725951874 1.2454752252283687 0.8178596390040305 0.6165125867574921 1.5651234767282163 1.0 13.696475760269259 -4.758558207966016 4.906529085536008 1.239142051213573 7.125367778565082 0.9405822022647277 0.4135010046218379 0.0433960900677134 2.646394172753716 0.1136843993054093 0.8898961747764312 1.7435796519250945e-05 4.758558207966016 5.886225727351509 up (ac)SETAPAET(ph)ATPAPVEKSPAK ddPTM_PC-9_Lapatinib_30min_R1 1 SETAPAETATPAPVEKSPAK 20 1 P16401 P16401 HIST1H1B Histone H1.5 1 S(0.003)ETAPAET(0.818)AT(0.121)PAPVEKS(0.057)PAK 99.711 5.318600000000001e-10 2080300000.0 144900.0 136080.0 118250.0 110560.0 93774.0 94918.0 100770.0 102590.0 84451.0 79081.0 True False 142833.69942859415 135764.91512072997 108527.9414582 118690.95121734831 88258.39768677746 90858.578404665 105987.37752860322 107356.70592320821 74939.2390715452 92750.04548119089 1.5399852225146338 1.4637719519853198 1.1701120025888156 1.2796861780668136 0.951572554265493 0.9796068339728257 1.1427204911732014 1.1574841323930074 0.8079698363785968 1.0 16.501060368727337 -5.200974688721392 0.8107006957413393 1.0157429683307104 1.7039140139345494 0.7412710523612474 0.11094725581051601 0.7938255726746938 0.6025645302224907 0.04542180104876842 0.4402425064933916 6.295428724108731e-06 5.200974688721392 0.688171045603839 (ac)SETAPAETATPAPVEKS(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 4 SETAPAETATPAPVEKSPAK 20 1 P16401 P16401 HIST1H1B Histone H1.5 1 S(0.01)ET(0.002)APAET(0.002)AT(0.004)PAPVEKS(0.982)PAK;S(0.004)ETAPAET(0.004)AT(0.015)PAPVEKS(0.977)PAK;S(0.071)ET(0.071)APAET(0.299)AT(0.125)PAPVEKS(0.435)PAK;S(0.324)ET(0.005)APAET(0.017)AT(0.034)PAPVEKS(0.62)PAK 97.271 0.00014473 401053400.0 766932.0 830929.0 838103.0 894369.0 981285.0 797704.0 925761.0 723330.0 776223.0 916268.0 True False 1010800.4228234135 1099510.5495477794 826989.2066132285 688186.044913307 845050.5159620531 747823.4427765749 1008151.9355633095 611555.9689698324 817252.5630893379 884189.7362102743 1.1431940243457308 1.2435233123835974 0.9353074037680952 0.7783239464675774 0.9557343648706262 0.8457725894691122 1.1401986409436844 0.691656941858455 0.9242954646727344 1.0 19.75399646183388 -5.315405322761579 5.801659063702261 0.8994294313907841 1.1931890257519688 0.4828138763139208 0.1176530888748469 0.14867325576975016 11.366373327844387 0.02970082568484285 0.06430373021423075 4.8372070508204395e-06 5.315405322761579 0.2937595943611847 (ac)SETAPAETATPAPVEKS(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SETAPAETATPAPVEKSPAK 20 1 P16401 P16401 HIST1H1B Histone H1.5 1 S(0.064)ET(0.002)APAET(0.005)AT(0.005)PAPVEKS(0.924)PAK;S(0.003)ET(0.001)APAETAT(0.003)PAPVEKS(0.993)PAK;S(0.092)ET(0.007)APAET(0.031)AT(0.065)PAPVEKS(0.805)PAK;S(0.01)ET(0.002)APAET(0.001)AT(0.099)PAPVEKS(0.888)PAK;S(0.128)ET(0.005)APAET(0.003)AT(0.051)PAPVEKS(0.813)PAK 78.987 2.7454000000000002e-05 5669319700.0 208088.5 211173.0 197040.1 255535.0 396519.0 240044.4 308053.8 384703.0 266929.4 176273.6 True False 243313.77311478357 232136.85984626212 201738.2832627403 241218.20240564822 318823.9483854576 227456.04908998485 278872.71394762554 374604.9538765215 270832.73749418865 208230.60829895016 1.168482266379713 1.1148066162924064 0.9688214663096549 1.1584185647642098 1.5311099121783867 1.092327640725293 1.3392493842560202 1.7989908253003464 1.3006384589981248 1.0 17.66782262374403 -6.07064301787104 6.690867401529262 1.3699228053729158 1.0831317707061663 0.2360512319994552 0.21241210767736668 0.3253262226668191 25.7214335252685 0.06321492620417818 0.08248354649396211 8.498787728257792e-07 6.07064301787104 -0.2867910346667495 (ac)SETAPAETATPAPVEKS(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 2 SETAPAETATPAPVEKSPAK 20 1 P16401 P16401 HIST1H1B Histone H1.5 1 S(0.026)ET(0.002)APAET(0.004)AT(0.014)PAPVEKS(0.954)PAK;S(0.001)ET(0.001)APAET(0.001)AT(0.012)PAPVEKS(0.985)PAK 72.09 3.0685e-05 23957000.0 59309.0 61108.0 59268.0 52360.0 40004.0 41545.0 46067.0 44759.0 45096.0 36761.0 True False 58463.24278406149 60966.508180464356 54395.21382109608 56210.72906783964 37651.04337089009 39768.21719612514 48452.12385243786 46838.6665407629 40016.81359806757 43115.08986904647 1.3559810025128556 1.4140410785559774 1.2616282138413895 1.3037367946713918 0.8732683495557511 0.9223735197331887 1.123785755743559 1.0863636532598229 0.9281393989809764 1.0 15.395905266709223 -6.180624275346808 6.2252122928042 0.997208625532599 1.3382679727438567 0.8206371604917699 0.07897950805762123 0.1076764239472026 6.732363087567022 0.02553221513996749 0.033088294274837594 6.597444183751849e-07 6.180624275346808 0.34105934721125764 (ac)SETAPAETATPAPVEKS(ph)PAKK ddPTM_PC-9_AZD4547_30min_R2 5 SETAPAETATPAPVEKSPAKK 21 2 P16401 P16401 HIST1H1B Histone H1.5 1 SETAPAETATPAPVEKS(1)PAKK;SETAPAETATPAPVEKS(0.999)PAKK;SETAPAETATPAPVEKS(1)PAKK;SETAPAETATPAPVEKS(1)PAKK;SETAPAETATPAPVEKS(0.999)PAKK 87.80799999999999 0.00015667 1118320000.0 370610.0 461332.0 374740.0 423864.0 467762.0 416829.0 466763.0 424526.0 405469.0 460088.0 True False 488456.2708331186 610448.5471610412 369770.70274923416 326148.7034335195 402821.3204598488 390764.6167364313 508304.00276025344 358925.2613369927 426901.2635586308 443980.4591598876 1.1001751558106618 1.3749446277796757 0.8328535527192452 0.7346014823505235 0.907295157138399 0.8801392238654989 1.144879222211898 0.8084258077847869 0.9615316502136725 1.0 18.76013665530609 -5.2685187789568175 24.992579183572396 0.9030185365966908 1.237559896945811 0.5322073808987844 0.12322820932430587 362.37422903227025 1279301.8087506103 0.03221998055483456 0.06944429228861747 5.388665442014555e-06 5.2685187789568175 0.3345413603491202 (ac)SETAPAETATPAPVEKS(ph)PAKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 SETAPAETATPAPVEKSPAKK 21 2 P16401 P16401 HIST1H1B Histone H1.5 1 SETAPAETATPAPVEKS(1)PAKK;SETAPAETATPAPVEKS(1)PAKK;SETAPAETATPAPVEKS(1)PAKK;S(0.002)ETAPAETAT(0.001)PAPVEKS(0.996)PAKK;S(0.005)ETAPAET(0.002)AT(0.007)PAPVEKS(0.986)PAKK;SETAPAETATPAPVEKS(1)PAKK;S(0.001)ETAPAETATPAPVEKS(0.999)PAKK;SETAPAETATPAPVEKS(1)PAKK 77.689 1.4448e-05 986084800.0 900236.0 799128.0 693233.0 1129272.0 1844076.0 1115070.0 1285991.0 1721078.0 1099408.0 772251.0 True False 1052628.1743285235 878460.1465870376 709762.3038207926 1066002.5509892232 1482742.5456103277 1056593.766231453 1164172.6227114245 1675901.526132874 1115484.762124408 912253.9931644455 1.1538762035747798 0.962955660560955 0.778031457400098 1.1685370072116117 1.6253615294869357 1.1582232296581336 1.2761496594529758 1.8370996879054178 1.2227787112830182 1.0 19.79907603529829 -6.001479002312997 16.921546180305526 1.38291990175089 0.9661697241586594 0.3441660060490559 0.2387171158010494 0.9298852821310369 10657.736341882912 0.06652858063163601 0.09584241356038309 9.966002635573059e-07 6.001479002312997 -0.41675017759223054 (ac)SETAPAETATPAPVEKS(ph)PAKK ddPTM_PC-9_Lapatinib_30min_R1 5 SETAPAETATPAPVEKSPAKK 21 2 P16401 P16401 HIST1H1B Histone H1.5 1 SETAPAETATPAPVEKS(1)PAKK;SETAPAETATPAPVEKS(1)PAKK;SETAPAETATPAPVEKS(0.999)PAKK;SETAPAETATPAPVEKS(1)PAKK;SETAPAETATPAPVEKS(1)PAKK 72.033 0.00025163 823367000.0 1218590.0 1173060.0 1090890.0 996337.0 854192.0 830424.0 982110.0 923533.0 795208.0 766962.0 True False 1201212.6831379626 1170343.8516425898 1001201.2351571742 1069610.9466628 803950.1059660857 794908.7013328935 1032958.8502988641 966443.7147029743 705643.301128528 899530.3597873745 1.3353775890586927 1.3010609802199766 1.1130266191280436 1.1890770945358955 0.8937442713507953 0.8836930212347576 1.1483312809397879 1.074386988929886 0.7844574598853158 1.0 19.778812448715726 -5.565753951109647 1.1244041450563118 0.9765430266640492 1.3544314409981753 0.6067571031060576 0.10828124812985952 0.4615861067673665 1.0307333691656395 0.03954574851940564 0.15079231100906243 2.717978699491294e-06 5.565753951109647 0.377888414334126 (ac)SETAPLAPT(ph)IPAPAEKTPVK ddPTM_PC-9_Lapatinib_30min_R1 1 SETAPLAPTIPAPAEKTPVK 20 1 P16402 P16402 HIST1H1D Histone H1.3 1 S(0.089)ET(0.089)APLAPT(0.66)IPAPAEKT(0.162)PVK 68.845 0.00043933 0.0 4440.1 10692.0 3558.5 4318.3 4107.4 4800.5 4407.1 4011.8 2790.9 3552.8 True False 4376.783359785381 10667.243330914525 3265.9338662072328 4635.88218742651 3865.8108074591 4595.193805512064 4635.2780738940855 4198.202873795945 2476.5594525201054 4166.8967461915745 1.0503700058768284 2.559997038722902 0.7837808482276898 1.1125502909721905 0.927743364649566 1.1027856185090117 1.1124053117300299 1.007513055760977 0.5943414496132189 1.0 12.024757635817744 -5.290274052774183 24.999918969670368 0.9709412911941491 1.805183938522542 0.4558208789280913 0.37119266923213423 498.9968906352314 432633.8997741931 0.08889277531629226 0.18509519367412886 5.125378552469949e-06 5.290274052774183 0.834242647328393 (ac)SETAPLAPTIPAPAEKT(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 5 SETAPLAPTIPAPAEKTPVK 20 1 P16402 P16402 HIST1H1D Histone H1.3 1 S(0.002)ET(0.002)APLAPT(0.001)IPAPAEKT(0.996)PVK;S(0.033)ET(0.033)APLAPT(0.035)IPAPAEKT(0.899)PVK;S(0.076)ET(0.076)APLAPTIPAPAEKT(0.847)PVK;S(0.023)ET(0.023)APLAPTIPAPAEKT(0.954)PVK;S(0.024)ET(0.024)APLAPT(0.011)IPAPAEKT(0.942)PVK 85.166 7.450000000000001e-28 0.0 153971.4 200804.0 181795.0 194294.9 201489.2 178318.4 227243.0 195568.0 189068.8 212354.4 True False 202931.10239592663 265709.96606375766 179384.27951725735 149503.2126312812 173515.90253675726 167168.12225889607 247467.18677197714 165347.45930556205 199062.59077639453 204919.93709164913 0.9902945768774416 1.296652584589271 0.8753871490650951 0.7295688977515977 0.8467497355279461 0.8157728556403528 1.2076286489454613 0.8068881029941536 0.9714164156090145 1.0 17.64470082844919 -5.282296290421251 24.595872460641075 0.8988158282310785 1.1434735902072364 0.30319295288158876 0.1431967958620742 664.5837435285517 783721.2492550642 0.037476937234958596 0.07815604768443388 5.220399141512178e-06 5.282296290421251 0.24465776197615785 (ac)SETAPLAPTIPAPAEKT(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 SETAPLAPTIPAPAEKTPVK 20 1 P16402 P16402 HIST1H1D Histone H1.3 1 SETAPLAPT(0.008)IPAPAEKT(0.991)PVK;S(0.299)ET(0.299)APLAPT(0.022)IPAPAEKT(0.381)PVK;S(0.001)ET(0.001)APLAPTIPAPAEKT(0.998)PVK;S(0.003)ET(0.003)APLAPT(0.002)IPAPAEKT(0.992)PVK;SETAPLAPT(0.007)IPAPAEKT(0.993)PVK;SETAPLAPTIPAPAEKT(1)PVK;SETAPLAPTIPAPAEKT(1)PVK 91.889 7.450000000000001e-28 12794000.0 110519.8 123891.7 125617.70000000001 151288.4 228126.5 134601.2 183978.2 173846.2 141628.0 95024.4 True False 129228.61927444968 136190.849204279 128612.90237577986 142812.2014316108 183426.74994478264 127542.47612012958 166550.45300917875 169282.92145527434 143699.04156614802 112251.57150726336 1.1512410698507487 1.213264521605977 1.1457559181472825 1.2722512434702973 1.6340684364754199 1.1362199602869418 1.4837249115786493 1.508067274089973 1.2801517131263487 1.0 16.776376117085775 -6.00128827673603 23.36368408505243 1.3709558147114222 1.1801712027847753 0.14619469463116253 0.17458972711499418 33.340679615127726 604732.0783601861 0.04676003772475215 0.06818048127921929 9.970380285108687e-07 6.00128827673603 -0.19078461192664697 (ac)SETAPLAPTIPAPAEKT(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 3 SETAPLAPTIPAPAEKTPVK 20 1 P16402 P16402 HIST1H1D Histone H1.3 1 S(0.01)ET(0.01)APLAPT(0.001)IPAPAEKT(0.98)PVK;SETAPLAPT(0.003)IPAPAEKT(0.997)PVK;S(0.004)ET(0.004)APLAPT(0.002)IPAPAEKT(0.989)PVK 90.22 7.0267e-28 0.0 155790.0 229248.0 231347.0 196336.0 187995.0 179701.0 206216.0 195741.0 174573.0 159829.0 True False 153568.40603161303 228717.1903409555 212326.54268524548 210775.20439769636 176937.50371239087 172015.60713349117 216892.85545736286 204835.84144765203 154910.75040481283 187455.22969124388 0.8192271097720476 1.2201163484084914 1.1326786829845557 1.1244029027350297 0.9438920642748848 0.9176356798197458 1.1570381675379529 1.0927187349482628 0.8263879896013847 1.0 17.51618654943266 -6.253574031030718 24.324457305944374 0.9990205239664649 1.0887192974440616 0.08650395489507445 0.12896181615225044 1059.1546560062732 3275548.648934693 0.038482959854380924 0.04872620526939639 5.577325214194597e-07 6.253574031030718 0.0896987734775967 (ac)SETAPLAPTIPAPAEKT(ph)PVKK ddPTM_PC-9_AZD4547_30min_R2 2 SETAPLAPTIPAPAEKTPVKK 21 2 P16402 P16402 HIST1H1D Histone H1.3 1 SETAPLAPTIPAPAEKT(1)PVKK;SETAPLAPT(0.001)IPAPAEKT(0.999)PVKK 80.83 2.3431e-05 193598000.0 159630.0 168783.0 162000.0 223516.0 201662.0 203097.0 208658.0 198645.0 182497.0 226488.0 True False 210389.01948973452 223338.8040185416 159851.77415108052 171987.83948777584 173664.71223950174 190397.312483822 227228.15777589314 167948.97965798763 192143.4188449904 218558.72405758244 0.9626200939675348 1.021870918132281 0.7313904985507019 0.7869182080439999 0.7945906208426952 0.8711494510448327 1.0396663814528246 0.7684386902521404 0.8791386373319394 1.0 17.73766144077092 -11.058935349448946 14.512323736265566 1.0000000240387177 0.8700404490346222 0.12360956627343311 0.10130604895325723 8.268181840976458e-08 2.6406810236147156e-09 0.10287093706158072 0.02494986218515415 8.731013315429822e-12 11.058935349448946 -0.1299595750040955 (ac)SETAPLAPTIPAPAEKT(ph)PVKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SETAPLAPTIPAPAEKTPVKK 21 2 P16402 P16402 HIST1H1D Histone H1.3 1 SETAPLAPT(0.01)IPAPAEKT(0.99)PVKK;SETAPLAPT(0.008)IPAPAEKT(0.992)PVKK;SETAPLAPT(0.002)IPAPAEKT(0.998)PVKK 58.373000000000005 0.00026937 138683000.0 271441.0 274727.0 305447.0 350716.0 627440.0 367858.0 457004.0 496600.0 394412.0 297338.0 True False 317390.60009587323 302000.08095250936 312730.0148941978 331066.51955661335 504497.6361157273 348566.878903001 413713.27269756433 483564.776191192 400179.5293458037 351243.02567368693 0.9036210740045743 0.8598037793726175 0.890352240572974 0.9425568491263994 1.4363207216658518 0.9923809255271245 1.1778547685154999 1.376724207587356 1.1393237732713872 1.0 18.42211005371805 -6.073360518394695 8.997509863317484 1.1957213474196469 0.8876943044883778 0.5349286271628698 0.132233246030579 0.2978328100337526 34.70005675132076 0.037725498526735735 0.04883004153497789 8.445774498293149e-07 6.073360518394695 -0.30802704293126904 (ac)SETAPLAPTIPAPAEKT(ph)PVKK ddPTM_PC-9_Lapatinib_30min_R1 1 SETAPLAPTIPAPAEKTPVKK 21 2 P16402 P16402 HIST1H1D Histone H1.3 1 SETAPLAPTIPAPAEKT(1)PVKK 69.07 5.893200000000001e-06 47773000.0 135430.0 145800.0 163660.0 118010.0 113440.0 114390.0 129640.0 126720.0 119030.0 119360.0 True False 133498.7433651798 145462.40905792528 150204.50654586952 126688.84906981993 106767.68223162102 109497.80635611388 136352.1248666083 132607.87381410357 105623.58795853247 139991.21696279696 0.9536222790366731 1.0390823954090085 1.0729566454571702 0.9049771251255558 0.7626741487645958 0.7821762588521052 0.974004854196276 0.9472585258641224 0.7545015340969728 1.0 17.09497678988059 -5.895963547231585 5.600779245861622 0.8654424984819035 1.0223360370566568 0.3827768266320992 0.08610541945060672 0.21388664336560842 9.88005971349925 0.025086576295541986 0.0377323906987412 1.2706807560857102e-06 5.895963547231585 0.1568935385747533 (ac)SGDHLHNDS(ph)QIEADFR ddPTM_PC-9_AZD4547_30min_R2 1 SGDHLHNDSQIEADFR 16 0 P11387 P11387 TOP1 DNA topoisomerase 1 1 S(0.028)GDHLHNDS(0.972)QIEADFR 46.833 0.0071289000000000005 20722000.0 4283.6 3414.5 5510.8 5949.6 5780.4 6217.4 4075.3 4938.0 0.0 0.0 True False 5645.695695584964 4518.170350813239 5437.7231913072455 4578.011640403687 4977.891236966897 5828.624995134897 4437.993805097803 4174.945563951495 0.0 0.0 0.0 (ac)SGDHLHNDS(ph)QIEADFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGDHLHNDSQIEADFR 16 0 P11387 P11387 TOP1 DNA topoisomerase 1 1 S(0.001)GDHLHNDS(0.999)QIEADFR 49.768 0.0016981 8816400.0 7593.8 5704.4 6946.7 8122.5 8368.4 8921.7 6206.1 9031.9 3472.5 7277.5 True False 8879.280355613344 6270.695132933754 7112.335673506455 7667.422658500303 6728.672093062041 8453.83034624477 5618.2132797269805 8794.822195089084 3523.278743175423 8596.8531413417 1.0328523948970898 0.7294175007804187 0.8273185032443676 0.8918871280501668 0.782690128868702 0.9833633548525863 0.6535197458136586 1.023028083706044 0.4098335385342583 1.0 13.069592945848926 -7.261798262873204 24.999581629648223 0.7735143587098204 0.8624500084176098 0.06926079536093144 0.1816679297629485 110.39413583685118 7689553.769816816 0.06730229514957087 0.04857087854144425 5.472701200793624e-08 7.261798262873204 0.08893564970778933 (ac)SGGKY(ph)VDSEGHLYTVPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGGKYVDSEGHLYTVPIR 18 1 Q03135 Q03135 CAV1 Caveolin-1 1 S(0.216)GGKY(0.782)VDS(0.002)EGHLYTVPIR;S(0.445)GGKY(0.554)VDSEGHLYTVPIR 79.393 3.615e-05 10774100.0 29321.0 10206.3 25306.0 40879.0 60683.0 55240.0 45203.0 60851.0 45578.0 30292.0 True False 34284.466183852455 11219.514012913152 25909.391013539436 38588.68216150615 48792.60176656042 52343.11715553774 40921.04459862048 59253.725726963945 46244.492024895415 35783.699808659934 0.9581028895048842 0.3135370035213056 0.724055677643181 1.0783871530290277 1.3635426752253335 1.4627642595769343 1.1435666188077418 1.655885949295385 1.2923340032520585 1.0 15.127014940210774 -5.883480790704894 2.473303756025248 1.3486258694261943 0.6120136620461398 0.6354228887676145 0.22097892439993594 0.15797275377233463 1.9618354407986607 0.06355241011870792 0.10566961382391571 1.3077333800439648e-06 5.883480790704894 -0.7366122073800545 (ac)SGGSSCSQT(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 1 SGGSSCSQTPSR 12 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 SGGSSCSQT(0.774)PS(0.226)R 185.66 1.3188999999999997e-38 2629300.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)SGGSSCSQTPS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 SGGSSCSQTPSR 12 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 SGGSSCSQT(0.274)PS(0.726)R;SGGSSCSQT(0.003)PS(0.997)R 195.71 5.3594e-21 5958400.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)SGGSSCSQTPS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGGSSCSQTPSR 12 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 SGGSSCSQT(0.047)PS(0.953)R 136.33 0.0051424999999999995 2298900.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)SGGSSCSQTPS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 SGGSSCSQTPSR 12 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 SGGSSCSQT(0.003)PS(0.997)R 195.71 7.843500000000001e-22 2919100.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)SGTSS(ph)PEAVKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGTSSPEAVKK 11 1 A0A286YFF8;Q7Z3U7-2;Q7Z3U7-6;Q7Z3U7-5;Q7Z3U7;F8VZV6;F8VQS2;F8VZV1 A0A286YFF8 MON2 Protein MON2 homolog 1 S(0.057)GT(0.057)S(0.097)S(0.79)PEAVKK 57.836000000000006 0.0078028 5133400.0 52072.0 57572.0 49830.0 63410.0 70134.0 67842.0 67052.0 60452.0 65624.0 47041.0 True False 60886.76113111983 63287.36767990713 51018.136181327354 59857.34327799374 56391.74616113163 64284.2460909846 60700.34914555891 58865.19905418853 66583.62685158927 55569.1609236489 1.0956933687513695 1.1388937070124725 0.918101611277259 1.0771683841013315 1.0148029090922022 1.1568331251089086 1.0923387745400759 1.059314160511949 1.198211845290845 1.0 15.761996835773969 -6.749279293792538 24.99853350207738 1.1044841738301074 1.0482302079166184 0.11207010723323296 0.07347854083681642 498.23006652823886 1024251.823552262 0.023909388106808843 0.02374418486318371 1.7812328922151174e-07 6.749279293792538 -0.05625396591348908 (ac)SGTSS(ph)PEAVKK ddPTM_PC-9_Lapatinib_30min_R1 2 SGTSSPEAVKK 11 1 A0A286YFF8;Q7Z3U7-2;Q7Z3U7-6;Q7Z3U7-5;Q7Z3U7;F8VZV6;F8VQS2;F8VZV1 A0A286YFF8 MON2 Protein MON2 homolog 1 S(0.014)GT(0.014)S(0.099)S(0.874)PEAVKK;S(0.03)GT(0.03)S(0.42)S(0.521)PEAVKK 69.01 0.008949200000000001 9924300.0 111691.0 107949.0 108203.0 97492.0 103188.0 99777.0 94255.0 85111.0 114729.0 76979.0 True False 110098.26585837887 107699.05072286662 99306.96701565883 104661.88690377829 97118.68471541358 95509.77030154719 99135.06270674312 89065.5677729812 101807.0118700704 90284.71758193018 1.219456280166891 1.1928824014444477 1.0999310810884608 1.1592425573996101 1.075693509560816 1.0578730582490383 1.0980270566475614 0.986496609375306 1.127621757000947 1.0 16.4621941841474 -1.5228787452808215 0.24297915457310434 1.0200932748173839 2.2880689826883 0.6627583059264985 0.0420343603253286 28.297541890149912 0.38016422492161256 0.05288492759997689 14.526908913646668 0.029999999999966574 1.5228787452808215 1.2679757078709162 (ac)SGYSS(ph)DRDR ddPTM_PC-9_AZD4547_30min_R2 2 SGYSSDRDR 9 1 P17844-2;P17844;J3QRQ7;J3QR02;J3KRX8;X6RLV5;J3QKN9;J3QS79 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 1 SGYS(0.018)S(0.982)DRDR;SGYS(0.007)S(0.993)DRDR 89.04700000000001 0.0025263 718980000.0 1040.9 878.79 1545.42 2739.73 1608.7800000000002 1306.98 1587.7 2580.2200000000003 527.09 1457.67 True False 1371.8845479350057 1162.841681824913 1524.9267210405094 2108.1275769065483 1385.4286665641828 1225.2543339887095 1729.002224217549 2181.5062865570944 554.9509013244377 1406.6374169802177 0.975293655190959 0.8266818924249237 1.0840936709292408 1.4987000569288822 0.9849223757593722 0.8710519990425798 1.2291740596019314 1.5508661011167841 0.3945230623224935 1.0 10.458034783714869 (ac)SGYSS(ph)DRDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGYSSDRDR 9 1 P17844-2;P17844;J3QRQ7;J3QR02;J3KRX8;X6RLV5;J3QKN9;J3QS79 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 1 SGYS(0.036)S(0.964)DRDR;SGYS(0.029)S(0.971)DRDR 72.848 0.0031526 650610000.0 870.41 2072.21 9481.7 3280.0699999999997 5365.200000000001 4717.7 2417.95 2508.5 4653.0 2154.49 True False 1017.7532216188742 2277.925314041207 9707.779687547494 3096.298312030419 4313.927574410458 4470.2955069638 2188.904271557958 2442.6545329754485 4721.041322388835 2545.0819820665442 0.3998901523763425 0.8950302308892963 3.814328872685278 1.2165809721839689 1.695005349457409 1.756444601180992 0.8600525590066146 0.9597547545372479 1.854966305861576 1.0 11.313496413739438 -7.243808594405525 23.520262053866706 1.1653396155120146 1.679672137691286 0.060584877968775874 0.8757416564224947 1156.6171943286167 1542980.498089854 0.3468287894891592 0.2678885660033032 5.7041561483390246e-08 7.243808594405525 0.5143325221792714 (ac)SGYSS(ph)DRDR ddPTM_PC-9_Lapatinib_30min_R1 1 SGYSSDRDR 9 1 P17844-2;P17844;J3QRQ7;J3QR02;J3KRX8;X6RLV5;J3QKN9;J3QS79 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 1 SGYS(0.005)S(0.995)DRDR 92.23899999999999 0.0023351 402780000.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)SHTILLVQPTK ddPTM_PC-9_Lapatinib_30min_R1 1 SHTILLVQPTK 11 0 P84090;G3V279 P84090 ERH Enhancer of rudimentary homolog 0 79.148 0.00076611 8534000.0 79994.0 91441.0 92577.0 87318.0 94773.0 91932.0 83488.0 84677.0 76223.0 86247.0 False True 78853.27089089717 91229.27398261825 84965.67641755448 93739.65700430928 89198.63847088708 88000.28266395908 87810.6001300787 88611.40254858634 67637.96307622636 101154.67903309643 0.7795316207280679 0.9018789328842542 0.8399579458875538 0.9266962032832801 0.8818043744837795 0.8699576085369871 0.8680824354288967 0.8759990481467881 0.6686587681633208 1.0 16.62620352949581 -9.680394321536895 9.54405610585426 0.9999996739589437 0.853002275331632 0.29822986845213784 0.07017381987096905 88339812.80290128 0.0 0.06596128011469532 0.016490320028673837 2.0873999967887028e-10 9.680394321536895 -0.14699739862731176 (ac)SIFT(ph)PTNQIR ddPTM_PC-9_Lapatinib_30min_R1 1 SIFTPTNQIR 10 0 F8WE72;A0A087X020;Q9Y3A5 F8WE72 SBDS Ribosome maturation protein SBDS 1 S(0.003)IFT(0.987)PT(0.01)NQIR 90.82700000000001 0.0027399 0.0 724.19 528.04 0.0 0.0 0.0 529.93 598.06 0.0 0.0 0.0 True False 713.862917799819 526.8173558226811 0.0 0.0 0.0 507.2661292271655 629.024620469946 0.0 0.0 0.0 0.0 (ac)SKGPAVGIDLGTT(ph)YSCVGVFQHGK ddPTM_PC-9_Lapatinib_30min_R1 1 SKGPAVGIDLGTTYSCVGVFQHGK 24 1 P11142;E9PKE3;P11142-2;E9PNE6;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65;E9PPY6;E9PN25 P11142 HSPA8 Heat shock cognate 71 kDa protein 1 S(0.226)KGPAVGIDLGT(0.301)T(0.443)Y(0.028)S(0.002)CVGVFQHGK 59.163000000000004 3.2789e-07 1166400.0 10077.0 7653.8 11709.0 11152.0 9127.1 9917.0 7399.7 10401.0 12302.0 8753.8 True False 9933.300132104532 7636.078096348071 10746.331218047075 11972.15528198143 8590.261922569016 9492.873027656113 7782.820258989832 10884.268430717286 10916.419214196978 10266.882666294692 0.967508878300004 0.7437581926806927 1.0466985517742764 1.166094487597974 0.8366962204379835 0.9246110368846828 0.7580509597660225 1.0601337119055056 1.0632652158414801 1.0 13.325710582181665 (ac)SKSES(ph)PKEPEQLR ddPTM_PC-9_Lapatinib_30min_R1 1 SKSESPKEPEQLR 13 2 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8W646 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 S(0.133)KS(0.374)ES(0.493)PKEPEQLR 52.93 0.0065693 50838000.0 387990.0 75835.0 97726.0 123540.0 58149.0 69184.0 34345.0 33437.0 97916.0 56464.0 True False 382457.19145134726 75659.40871678854 89691.34551326919 132625.54371735913 54728.79014533259 66225.16159578106 36123.21604862436 34990.60508776982 86887.6689788092 66223.72716644923 5.7752290276574865 1.1424818860862862 1.3543687338502641 2.002689208114383 0.8264226809188068 1.000021660353369 0.5454724098785757 0.5283696129005713 1.3120322986415796 1.0 16.015060589517716 -4.761316347185776 7.483968942443179 1.069920575664089 5.852558269349614 0.9233950806509625 0.40583117833351545 0.02737511621738068 10.854787570896688 0.11117066117217976 0.663001057972285 1.732541526494738e-05 4.761316347185776 4.782637693685524 (ac)SLLDGLAS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 2 SLLDGLASSPR 11 0 E9PI10;E9PK87;F8W6N5;Q3YBR2 E9PI10 TBRG1 Transforming growth factor beta regulator 1 1 SLLDGLAS(0.781)S(0.219)PR;SLLDGLAS(0.63)S(0.369)PR 130.56 0.00029671 1128540.0 0.0 581.37 789.13 708.28 1188.38 0.0 1631.79 0.0 618.32 673.64 True False 0.0 769.2864831900109 778.6656205916173 544.9969888169159 1023.3939499319627 0.0 1777.0161488039014 0.0 651.0031328747018 650.0560686400585 0.0 1.1834155856730741 1.1978437832610576 0.83838458728194 1.5743164310010072 0.0 2.7336351963015826 0.0 1.0014568962283894 1.0 9.344420348624126 -4.7573426320732075 24.714961385427603 1.060354331043629 1.7813523345992535e-06 0.15734390691049405 0.7350617874508913 191.31402550429195 1153982.7152207494 0.1692966656357425 1.2619178506497006 1.7484667098772483e-05 4.7573426320732075 -1.0603525496912944 (ac)SLLDGLAS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLLDGLASSPR 11 0 E9PI10;E9PK87;F8W6N5;Q3YBR2 E9PI10 TBRG1 Transforming growth factor beta regulator 1 1 SLLDGLAS(0.768)S(0.232)PR;SLLDGLAS(0.5)S(0.5)PR 106.54 0.00026574 470340.0 0.0 598.63 2156.18 1256.97 1077.45 1109.48 1156.6 510.58 0.0 672.33 True False 0.0 658.0580301921555 2207.591508558186 1186.5460460517231 866.3314070395418 1051.2969156720856 1047.0384749411419 497.17781600422745 0.0 794.2181068386487 0.0 0.8285608506352585 2.779578417502227 1.4939800992131984 1.0907978546194785 1.323687922272042 1.318326119645942 0.6259965766623258 0.0 1.0 9.633391442035427 -7.819847879863863 4.389615413390147 0.44840446318793536 1.310651137164034 0.18561212732615706 0.6856892308327832 0.34106040319458647 13.168069967309131 0.41285652678412554 0.19369242694862507 1.514091495724742e-08 7.819847879863863 0.8622466739760986 (ac)SLLDGLAS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 SLLDGLASSPR 11 0 E9PI10;E9PK87;F8W6N5;Q3YBR2 E9PI10 TBRG1 Transforming growth factor beta regulator 1 1 SLLDGLAS(0.725)S(0.275)PR 92.295 0.00022235 561700.0 0.0 821.43 653.6 0.0 0.0 0.0 0.0 0.0 493.55 513.1 True False 0.0 819.5280293035088 599.8635309689613 0.0 0.0 0.0 0.0 0.0 437.9612016880931 601.7886513372256 0.0 1.3618203458680183 0.9968010025380397 0.0 0.0 0.0 0.0 0.0 0.7277658040159216 1.0 9.233113090042046 -8.49172027216891 5.952126583766919 0.9994126736340887 0.3157028975571199 0.20353843858231502 0.46441158914280917 0.2896873839573889 32.190948788258254 0.49774115940137537 0.12903795912664956 3.2231441407517694e-09 8.49172027216891 -0.6837097760769688 (ac)SLLDGLASS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 SLLDGLASSPR 11 0 E9PI10;E9PK87;F8W6N5;Q3YBR2 E9PI10 TBRG1 Transforming growth factor beta regulator 1 1 SLLDGLAS(0.375)S(0.625)PR 108.72 1.1835e-06 0.0 1004.3 0.0 771.02 0.0 542.68 0.0 490.24 504.64 531.79 0.0 True False 989.9784978339359 0.0 707.6297118232685 0.0 510.76062934993024 0.0 515.6222284372571 528.0874166788935 471.8942102030409 0.0 0.0 (ac)SLYPS(ph)LEDLKVDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLYPSLEDLKVDK 13 1 B4DHN5;E9PBU7;O00560-2;O00560 B4DHN5 SDCBP Syntenin-1 1 S(0.12)LY(0.087)PS(0.793)LEDLKVDK 62.732 0.011906 0.0 3654.7 4543.5 7489.1 5909.5 9613.6 8769.1 8170.4 9902.6 9241.6 6047.5 True False 4273.368526384695 4994.548653054575 7667.668546569912 5578.409873857497 7729.884091805038 8309.232958881717 7396.440563426519 9642.667242671989 9376.740916610506 7143.863878016344 0.598187283430055 0.6991382728363834 1.0733223193355435 0.7808673246173986 1.0820312682037576 1.1631286794883562 1.0353557528143031 1.3497831715894193 1.312558732462043 1.0 12.802488875706086 -4.904691264499405 0.46817483867779697 1.2204645501985183 0.20620533720476633 0.6655961401417099 0.136736105605914 2.5782726118793953 0.4770126822640391 0.09650723791336215 1.436299619886602 1.2453996390078696e-05 4.904691264499405 -1.014259212993752 (ac)SLYPS(ph)LEDLKVDK ddPTM_PC-9_Lapatinib_30min_R1 2 SLYPSLEDLKVDK 13 1 B4DHN5;E9PBU7;O00560-2;O00560 B4DHN5 SDCBP Syntenin-1 1 S(0.002)LYPS(0.998)LEDLKVDK;S(0.025)LY(0.001)PS(0.974)LEDLKVDK 79.88600000000001 0.0095479 6311300.0 46170.7 48714.9 47509.2 47265.3 54014.6 43239.3 40458.3 41987.3 53785.9 40702.2 True False 45512.297351330584 48602.103642084556 43603.17696681545 50741.34783441865 50837.567424789464 41390.05593473135 42553.03281001772 43938.18324017459 47727.96555136376 47737.5210377276 0.9533862748206302 1.0181111751419532 0.9133942445891834 1.0629238119490345 1.0649394086595292 0.8670340443949788 0.8913959477784255 0.9204119167698226 0.9997998327907248 1.0 15.542836030187102 -6.762462571578659 24.99999985125987 0.9279833256267725 1.00181632674309 0.2442572655233739 0.05796802065306688 38.71012815180656 945800.2887493925 0.020379684049743368 0.01900416856385196 1.7279748946393277e-07 6.762462571578659 0.07383300111631741 (ac)SQGDS(ph)NPAAIPHAAEDIQGDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQGDSNPAAIPHAAEDIQGDDR 22 0 P68402-3;P68402-2;P68402-4;P68402 P68402-3 PAFAH1B2 Platelet-activating factor acetylhydrolase IB subunit beta 1 S(0.379)QGDS(0.621)NPAAIPHAAEDIQGDDR 95.57 7.6683e-24 0.0 4875.9 5220.3 5981.3 4981.0 7238.7 6116.1 6564.9 5066.4 4705.4 4462.8 True False 5701.29356658525 5738.536884239199 6123.916876206571 4701.930718619884 5820.328698442739 5795.360949221295 5943.025146239933 4933.412368294522 4774.20757325778 5271.870312494635 1.081455580019269 1.088520116027615 1.1616213057617402 0.8918904373417605 1.1040348782192584 1.0992988457030055 1.1273086768000764 0.9357992658890055 0.9056003448989695 1.0 12.364099165284578 -7.773429801509138 24.984357374208734 0.9405247827082629 1.0772213487377746 0.42108155067953323 0.07078910274624405 219.60039552853505 457572.7871491062 0.03856113256060618 0.018746241367366346 1.6848847461631337e-08 7.773429801509138 0.13669656602951175 (ac)SQPGQKPAAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 SQPGQKPAASPR 12 1 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;F8W7E0;E9PSG1 P20810-6 CAST Calpastatin 1 SQPGQKPAAS(1)PR;SQPGQKPAAS(1)PR;SQPGQKPAAS(1)PR;SQPGQKPAAS(1)PR 105.95 0.00021932 281029000.0 63025.0 88378.0 96991.0 103026.0 96779.0 105517.0 105836.0 138422.0 111351.0 104089.0 True False 83065.63899856262 116944.46017401447 95704.8359672063 79274.94743583276 83342.90637714004 98919.0053095584 115255.19896850051 117032.06052112051 117236.7865324279 100444.87579222574 0.8269773678687923 1.1642650682939644 0.9528095406795624 0.7892383440228068 0.8297377613322774 0.9848088768029973 1.147447274532058 1.1651371918982312 1.1671753845854407 1.0 16.616044441119165 -7.140150378795679 3.96514195320033 1.1334218906582012 0.9209504920212742 0.44899161904582985 0.10748477210918757 0.23281185870026502 6.326923835815253 0.045456025492116914 0.034604502049722236 7.241851603223099e-08 7.140150378795679 -0.212471398636927 (ac)SQPGQKPAAS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SQPGQKPAASPR 12 1 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;F8W7E0;E9PSG1 P20810-6 CAST Calpastatin 1 SQPGQKPAAS(1)PR;SQPGQKPAAS(1)PR;SQPGQKPAAS(1)PR;S(0.426)QPGQKPAAS(0.574)PR 94.54700000000001 0.0013120999999999999 187023800.0 88890.0 113393.0 106007.0 107629.0 120679.0 101872.0 114819.0 110977.0 95785.0 83157.0 True False 103937.32134247299 124649.90765177013 108534.60891378642 101598.89606792587 97032.81625145022 96529.65298459343 103942.51310242698 108063.97133985098 97185.67441758308 98232.7058295502 1.058072466443317 1.2689247089259466 1.1048724352774288 1.0342675100919703 0.9877852333602416 0.9826630771230933 1.0581253180868724 1.1000813876323392 0.9893413155717822 1.0 16.583915818370095 -5.615332063940719 3.7048083866239803 1.024398017920823 1.1683847715442377 0.48941909732284383 0.05879418784750682 0.1750012750156284 4.616979681880719 0.016013770703522657 0.02982338022986554 2.4247554048498435e-06 5.615332063940719 0.14398675362341473 (ac)SQPGQKPAAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 SQPGQKPAASPR 12 1 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;F8W7E0;E9PSG1 P20810-6 CAST Calpastatin 1 SQPGQKPAAS(1)PR;SQPGQKPAAS(1)PR;SQPGQKPAAS(1)PR 117.2 9.693600000000001e-05 214113000.0 71861.0 77002.0 86570.0 77407.0 83349.0 80738.0 83585.0 73035.0 88228.0 66529.0 True False 70836.2489623065 76823.70659998886 79452.54876986363 83099.76900218237 78446.57569043877 77285.02394947055 87912.62231545395 76428.472727376 78290.83355797193 78028.44900567965 0.9078259258639163 0.9845602159078787 1.0182510325699325 1.0649932180009574 1.0053586440597926 0.9904723845509862 1.12667396873485 0.9794949624311104 1.0033626780441731 1.0 16.2517126029649 -4.80202664559182 2.0005985368812804 1.02627093852747 0.8762804034005619 0.4268009981949221 0.04093465124475439 0.6765071470946065 3.0827027356486294 0.011000064192395242 0.18633100809999434 1.5775144803129398e-05 4.80202664559182 -0.14999053512690808 (ac)SQPGQKPAAS(ph)PRPR ddPTM_PC-9_AZD4547_30min_R2 2 SQPGQKPAASPRPR 14 2 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;F8W7E0;E9PSG1 P20810-6 CAST Calpastatin 1 S(0.005)QPGQKPAAS(0.995)PRPR;S(0.002)QPGQKPAAS(0.998)PRPR 65.956 0.01495 2299920000.0 77201.3 86414.4 114336.6 186802.0 157634.0 155760.0 130046.0 181507.0 131783.0 140957.0 True False 101749.70751320466 114346.16487430534 112820.42197779266 143737.68496213018 135749.2400609021 146020.30257699575 141619.8420675162 153459.2637659262 138748.78033967342 136022.1383339717 0.7480378470700202 0.8406437825110065 0.8294269106458799 1.0567227270697266 0.9979937216366975 1.073503948441656 1.041152887332212 1.1281932900447542 1.0200455752210502 1.0 17.05348195139318 -5.732424447429134 4.951031089896919 1.050466255674032 0.8047853776079003 0.8718662897259133 0.04207234724011226 0.059656288135621495 3.596585765524716 0.011557170763945591 0.019660198004102097 1.8517210030961512e-06 5.732424447429134 -0.2456808780661318 (ac)SQPGQKPAAS(ph)PRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 SQPGQKPAASPRPR 14 2 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;F8W7E0;E9PSG1 P20810-6 CAST Calpastatin 1 S(0.057)QPGQKPAAS(0.943)PRPR;S(0.002)QPGQKPAAS(0.998)PRPR;SQPGQKPAAS(1)PRPR;S(0.002)QPGQKPAAS(0.998)PRPR;SQPGQKPAAS(1)PRPR;S(0.005)QPGQKPAAS(0.995)PRPR;SQPGQKPAAS(1)PRPR;SQPGQKPAAS(1)PRPR 73.834 0.00010284 4349302100.0 183067.1 192802.8 279265.7 286987.69999999995 356671.8 274198.5 294328.7 278935.9 252660.2 244809.19999999998 True False 214056.74428996065 211942.9877946853 285924.4534090656 270908.70959567756 286784.52117993985 259819.04796112806 266447.7547807442 271614.12818201544 256354.8774388627 289191.1700514392 0.7401911484776171 0.7328819471112705 0.9887039544056877 0.9367807099625148 0.9916780001579188 0.8984335445474125 0.9213550840205474 0.9392199911695185 0.8864547191854585 1.0 18.141663977218656 -5.254042213338623 24.98937879743583 0.9419766200031082 0.7365365165867227 0.8378081095210527 0.03672277941112118 200.1511828662301 676153.8573626252 0.009227445638421788 0.023409611305723256 5.571315932182136e-06 5.254042213338623 -0.20544010341638552 (ac)SQPGQKPAAS(ph)PRPR ddPTM_PC-9_Lapatinib_30min_R1 6 SQPGQKPAASPRPR 14 2 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;F8W7E0;E9PSG1 P20810-6 CAST Calpastatin 1 SQPGQKPAAS(1)PRPR;SQPGQKPAAS(1)PRPR;S(0.015)QPGQKPAAS(0.985)PRPR;S(0.003)QPGQKPAAS(0.997)PRPR;S(0.013)QPGQKPAAS(0.987)PRPR;S(0.001)QPGQKPAAS(0.999)PRPR 86.738 0.00051915 946260500.0 179593.8 132595.2 172385.4 161184.7 161030.0 151124.3 130076.6 124043.5 170716.4 123635.4 True False 177032.75947853035 132288.18396102483 158212.53783888766 173038.76053439648 151558.53199716107 144661.06597694973 136811.3298783081 129807.01385306045 151488.52130861147 145005.61415618457 1.2208683126423612 0.9122969805744081 1.0910787058801599 1.1933245587858246 1.045190787123031 0.9976238976591366 0.943489882612059 0.8951861250919995 1.0447079734819384 1.0 17.145749232321783 -6.735908256851993 2.951060933175722 0.9641813803013467 1.0918465150119598 0.3268404983947285 0.0854829327139562 0.31785674369824835 5.68378440587111 0.03117457374050798 0.029416613042663364 1.836926346451683e-07 6.735908256851993 0.12766513471061314 (ac)SQSGAVSCCPGATNGS(ph)LGR ddPTM_PC-9_AZD4547_30min_R2 1 SQSGAVSCCPGATNGSLGR 19 0 A0A3B3ISQ4;Q9H6S3;Q9H6S3-3;E9PNY4;E9PM34;E9PN68;E9PLN2;E9PNT0;E9PLH1 A0A3B3ISQ4 EPS8L2 Epidermal growth factor receptor kinase substrate 8-like protein 2 1 SQSGAVS(0.004)CCPGAT(0.031)NGS(0.965)LGR 133.95 2.7831000000000003e-59 0.0 0.0 0.0 7510.1 10375.0 6477.2 8034.3 1479.2 12383.0 1254.1 2816.6 True False 0.0 0.0 7410.511166987829 7983.204042152126 5577.9525846104025 7531.913950913933 1610.845934409901 10469.491883031871 1320.3891657041065 2717.991691306317 0.0 0.0 2.7264657175703872 2.9371701420894523 2.052233125822962 2.7711320733633134 0.5926603600600775 3.8519219600704666 0.48579588007110613 1.0 11.408325330565223 -5.251685542124124 23.95737026571302 2.1591876911775083 7.091606057772298e-07 0.3814880486106762 1.0380891329785942 347.32620648697497 853093.7091550486 0.24497247063374877 0.6294523798105554 5.6016304972024195e-06 5.251685542124124 -2.1591869820169025 (ac)SQSGAVSCCPGATNGS(ph)LGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSGAVSCCPGATNGSLGR 19 0 A0A3B3ISQ4;Q9H6S3;Q9H6S3-3;E9PNY4;E9PM34;E9PN68;E9PLN2;E9PNT0;E9PLH1 A0A3B3ISQ4 EPS8L2 Epidermal growth factor receptor kinase substrate 8-like protein 2 1 SQSGAVSCCPGAT(0.083)NGS(0.917)LGR 82.367 6.0013e-08 4227700.0 0.0 0.0 1657.1 1450.4 1197.9 3375.2 0.0 3292.0 1645.7 0.0 True False 0.0 0.0 1696.6115485867463 1369.138790260244 963.1800941971011 3198.198570299982 0.0 3205.58848816232 1669.7652491414801 0.0 0.0 (ac)SQSGAVSCCPGATNGS(ph)LGR ddPTM_PC-9_Lapatinib_30min_R1 2 SQSGAVSCCPGATNGSLGR 19 0 A0A3B3ISQ4;Q9H6S3;Q9H6S3-3;E9PNY4;E9PM34;E9PN68;E9PLN2;E9PNT0;E9PLH1 A0A3B3ISQ4 EPS8L2 Epidermal growth factor receptor kinase substrate 8-like protein 2 1 S(0.002)QSGAVS(0.052)CCPGAT(0.006)NGS(0.939)LGR;SQSGAVSCCPGAT(0.024)NGS(0.976)LGR 149.74 1.7141999999999997e-53 8536500.0 0.0 0.0 1853.7 733.77 1127.0 2029.87 942.18 0.0 1539.0 1114.2 True False 0.0 0.0 1701.2959414889276 787.733893584964 1060.712075767251 1943.057191958083 990.9614702778537 0.0 1365.661613611538 1306.7879854218218 0.0 0.0 1.3018913247352526 0.6028016039118153 0.8116940832026863 1.4868955129939292 0.7583184734882441 0.0 1.0450521651916722 1.0 10.351809380507207 -5.239712309234456 24.119734162026575 0.8457024525497799 4.7035208728556183e-07 0.45425605521028767 0.38285649695484386 491.2806497819162 545378.6780968995 0.10073631920661402 0.26592050450175303 5.758212537193423e-06 5.239712309234456 -0.8457019821976927 (ac)SS(ph)PASTPSRR ddPTM_PC-9_AZD4547_30min_R2 1 SSPASTPSRR 10 1 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;E5RFR3;E5RG53;A0A3B3IS88 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 S(0.223)S(0.775)PAS(0.001)TPSRR 80.455 0.008023899999999999 63388000.0 0.0 0.0 0.0 393.85 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 303.05396742184234 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)SS(ph)PASTPSRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPASTPSRR 10 1 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;E5RFR3;E5RG53;A0A3B3IS88 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 S(0.222)S(0.777)PASTPSRR;S(0.165)S(0.835)PASTPSRR 82.75 0.00065848 51396840.0 2045.6 1758.95 2805.93 2207.4 1123.4 2161.6 1216.8 2322.7 2541.1 2503.6 True False 2391.879677558356 1933.5669315044238 2872.834012748783 2083.7265344873567 903.2778343943761 2048.241890720679 1101.535895130885 2261.7315861040765 2578.258780211107 2957.4828615133038 0.8087552116310367 0.6537880427530335 0.9713780763141238 0.7045608147399854 0.3054211559935063 0.6925625562788963 0.37245723701920086 0.7647488394731657 0.871774715506499 1.0 11.530154092895314 -10.116836475219921 7.6474204162272335 0.9999999666691091 0.6735663728078024 0.19008478176886323 0.1955706847422913 0.0 0.0 0.1969241600797701 0.04776112424970194 7.64123444605193e-11 10.116836475219921 -0.32643359386130666 (ac)SS(ph)PASTPSRR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPASTPSRR 10 1 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;E5RFR3;E5RG53;A0A3B3IS88 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 S(0.2)S(0.8)PASTPSRR 69.346 0.040385000000000004 62077000.0 0.0 0.0 0.0 501.78 444.21 483.48 388.79 479.62 425.74 0.0 True False 0.0 0.0 0.0 538.6825750890105 418.0824411504616 462.802687446927 408.91964383591977 501.90489613889264 377.7886779590489 0.0 0.0 (ac)SSAPRS(ph)PTPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSAPRSPTPR 10 1 Q9HBI1 Q9HBI1 PARVB Beta-parvin 1 S(0.069)S(0.069)APRS(0.832)PT(0.03)PR 46.129 0.043703 1508700.0 837.52 0.0 1015.8 0.0 950.48 830.57 1809.1 1231.4 1343.3 739.11 True False 825.5768112176421 0.0 932.2848451013939 0.0 894.5746351155784 795.0484572532355 1902.7663460057158 1288.6153394467142 1192.0034084238991 866.8641786978308 0.9523715842749334 0.0 1.075468185225782 0.0 1.0319663184829868 0.9171545863707576 2.1949993929429366 1.4865250763763493 1.3750751706160933 1.0 9.759662157767368 -6.818130377075327 2.209204731771183 1.5425777733176127 0.5288307896332788 0.46205444013027963 0.45338390356387087 0.2431354625065886 2.4339381100482944 0.1702768533724109 0.15125930482803113 1.5200911233213457e-07 6.818130377075327 -1.0137469836843338 (ac)SSAPTT(ph)PPSVDKVDGFSR ddPTM_PC-9_AZD4547_30min_R2 1 SSAPTTPPSVDKVDGFSR 18 1 Q16537-2;Q16537 Q16537-2 PPP2R5E Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform 1 S(0.265)S(0.265)APT(0.131)T(0.33)PPS(0.009)VDKVDGFSR 43.763999999999996 0.017655 19799000.0 13806.0 12404.0 17086.0 23055.0 16653.0 16348.0 14018.0 21585.0 19086.0 12224.0 True False 18196.020817360626 16413.35042655949 16859.428476205918 17740.025946199243 14341.018401703988 15325.756975659484 15265.57484353568 18249.534223955645 20094.846995158747 11796.041480696018 1.542553139299997 1.3914286799872315 1.4292445905515023 1.503896538108181 1.2157483868781551 1.299228813389625 1.2941269211809303 1.547089695625489 1.703524612730767 1.0 13.526015180297513 (ac)SSAPTT(ph)PPSVDKVDGFSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSAPTTPPSVDKVDGFSR 18 1 Q16537-2;Q16537 Q16537-2 PPP2R5E Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform 1 S(0.218)S(0.218)APT(0.129)T(0.431)PPS(0.003)VDKVDGFSR 65.477 0.0013643 2425700.0 12706.0 14579.0 18073.0 16391.0 16427.0 17257.0 14328.0 12667.0 14734.0 10463.0 True False 12524.810110004977 14545.243221231087 16587.107703797486 17596.448818773115 15460.796156724604 16518.95833803181 15069.83373255758 13255.555063156999 13074.501764101638 12271.515608928848 1.0206408490318692 1.1852849871818487 1.3516755576408654 1.4339262874725762 1.2598929626488198 1.3461220980734026 1.228033619709749 1.080188909470331 1.065434961806065 1.0 13.583025821415223 -7.759487981820482 2.912208591344384 1.04195093034097 1.2750217471976073 0.4636413699358828 0.10567839036678378 0.2554499091566734 4.388107685341025 0.06982363319028803 0.0320756373959566 1.7398508440574865e-08 7.759487981820482 0.23307081685663733 (ac)SSDASQGVIT(ph)TPPPPSMPHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSDASQGVITTPPPPSMPHK 20 0 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 S(0.136)S(0.136)DAS(0.136)QGVIT(0.296)T(0.296)PPPPSMPHK 62.68 5.1377e-10 15041000.0 10425.0 14253.0 16403.0 17132.0 21544.0 18171.0 22275.0 20805.0 15490.0 14390.0 True False 12189.746596864426 15667.94364520455 16794.109728723903 16172.1495826934 17322.60785489804 17218.080771782686 20164.95074296553 20258.89079471963 15716.511945799073 16998.793088822673 0.7170948274486398 0.9217091803715639 0.9879589474953162 0.9513704589608294 1.019049279815535 1.0129001913144178 1.1862577912207617 1.1917840689549066 0.9245663420736178 1.0 14.053144698466458 -3.9013988058206577 0.5822954840619511 1.0744736382794242 4.903419388893892e-16 0.5959443671244631 0.08180073992754977 6.725763939346532 0.8039666759150097 0.041388175247002404 6.114003875785252 0.00012548771004607383 3.9013988058206577 -1.0744736382794238 (ac)SSDASQGVIT(ph)TPPPPSMPHK ddPTM_PC-9_Lapatinib_30min_R1 1 SSDASQGVITTPPPPSMPHK 20 0 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 S(0.094)S(0.094)DAS(0.033)QGVIT(0.437)T(0.334)PPPPS(0.007)MPHK 51.092 5.9857e-22 0.0 1684.3 5749.9 8195.2 7410.9 6069.5 7167.0 6504.0 7202.1 10557.0 11230.0 True False 1660.2815731372095 5736.586459822804 7521.422290386829 7955.922308037675 5712.50394309612 6860.484117093008 6840.745295683584 7536.735858558698 9367.95948986161 13171.09053696559 0.12605498143661778 0.43554377245549036 0.5710553935740879 0.6040443109633801 0.43371533488920877 0.5208744179412158 0.5193757704788796 0.5722180587405666 0.7112516206285102 1.0 13.685087182025956 -14.522878745280025 0.08059280801798029 2.7033943267924974 1.4484241823239456e-15 0.7447234547325895 0.10604143385831785 140.7106152461359 0.7990983722365878 42.088750095057655 3.8400208524994848 3.000000000002161e-15 14.522878745280025 -2.703394326792496 (ac)SSDASQGVIT(ph)TPPPPSMPHKER ddPTM_PC-9_AZD4547_30min_R2 1 SSDASQGVITTPPPPSMPHKER 22 1 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 S(0.063)S(0.063)DAS(0.063)QGVIT(0.406)T(0.406)PPPPSMPHKER 42.705 6.6565e-05 7187900.0 6944.0 4904.5 13135.0 34900.0 22043.0 11956.0 6976.3 13151.0 8229.5 11900.0 True False 9152.047555827334 6489.783712275153 12960.82131774346 26854.344199624964 18982.70993987635 11208.389429959918 7597.177185116132 11118.81512991618 8664.49456914277 11483.3846220781 0.7969817137563686 0.5651455494922476 1.1286586441444122 2.3385391226898786 1.653058794475973 0.9760527752776413 0.6615799640212089 0.9682524356572544 0.754524458972166 1.0 13.487260305344433 -6.983071801868884 22.659042092121254 0.839925349783691 1.3054307164854058 0.1802213427451702 0.4590360842938518 158.67606252507017 212390.9675434333 0.18545328133880773 0.16348726920829454 1.039748250130372e-07 6.983071801868884 0.4655053667017147 (ac)SSDASQGVITT(ph)PPPPSMPHK ddPTM_PC-9_AZD4547_30min_R2 4 SSDASQGVITTPPPPSMPHK 20 0 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 S(0.035)S(0.035)DAS(0.035)QGVIT(0.237)T(0.658)PPPPS(0.001)MPHK;S(0.101)S(0.101)DAS(0.101)QGVIT(0.111)T(0.582)PPPPS(0.003)MPHK;S(0.005)S(0.005)DAS(0.005)QGVIT(0.053)T(0.933)PPPPSMPHK;S(0.018)S(0.018)DAS(0.089)QGVIT(0.137)T(0.738)PPPPSMPHK 89.04899999999999 2.3128000000000002e-17 42676900.0 54213.6 59364.8 75087.4 92294.0 77205.6 83294.2 61610.4 88518.0 64122.9 71786.2 True False 71452.39708706804 78553.3106580635 74091.69201476434 71017.04422808561 66486.93510566252 78085.800506605 67093.60624484016 74839.57704128364 67512.3055845052 69272.9869880186 1.0314611826890963 1.1339674247286322 1.069561097857368 1.0251765849272336 0.959781554058901 1.1272186158236637 0.9685392410817311 1.080357297920874 0.974583434610407 1.0 16.080005262418197 -5.692170098130069 4.298679564166754 1.0224923510926294 1.0864678985372032 0.1987941456119955 0.05412733129552147 0.31947137849916846 11.408023185283545 0.014120880621837665 0.024856497133290648 2.031561162839962e-06 5.692170098130069 0.06397554744457379 (ac)SSDASQGVITT(ph)PPPPSMPHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSDASQGVITTPPPPSMPHK 20 0 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 S(0.011)S(0.011)DAS(0.011)QGVIT(0.232)T(0.735)PPPPS(0.001)MPHK 47.726000000000006 0.0018398 19575000.0 4791.7 3808.3 7923.8 4778.2 7927.9 7774.2 8381.9 8287.8 5947.0 8450.4 True False 5602.840169611056 4186.362855822107 8112.7334431788395 4510.49294513341 6374.484905906335 7366.507266303064 7587.905752299122 8070.254031649962 6033.9636243813475 9982.390626670403 0.5612723824533269 0.41937477828579584 0.812704465952643 0.4518449651812385 0.6385729775866852 0.7379502107062044 0.760129114966326 0.8084490312459122 0.6044607799919325 1.0 13.285169644535722 -11.617411528980474 0.061266588290065704 1.9746665182741312 1.546638129943845e-11 0.5205385949815486 0.11746557900603692 155.97667911330961 1.2972338109318373 33.81306533043031 12.163997214376701 2.413173074959229e-12 11.617411528980474 -1.974666518258665 (ac)SSDASQGVITT(ph)PPPPSMPHK ddPTM_PC-9_Lapatinib_30min_R1 2 SSDASQGVITTPPPPSMPHK 20 0 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 S(0.003)S(0.003)DAS(0.003)QGVIT(0.242)T(0.738)PPPPS(0.01)MPHK;S(0.206)S(0.206)DAS(0.206)QGVIT(0.013)T(0.37)PPPPSMPHK 114.99 5.4744e-15 24950000.0 30717.9 44871.0 50946.0 37525.7 58732.0 65609.0 67802.0 63908.0 70384.0 52772.0 True False 30279.85711302706 44767.10395636603 46757.4165372471 40285.46516006549 55277.499231554706 62803.05601204889 71312.45580226608 66877.39898762433 62456.612743622194 61893.56988573007 0.48922460231217435 0.7232916769709119 0.7554486940012052 0.6508828822516108 0.8931056866425677 1.0146943556171981 1.152178747064121 1.0805225665783307 1.0090969523802171 1.0 15.917501915389149 -6.492059574908843 1.9137865618600565 1.069039834633566 0.6586057351466055 0.852689581950573 0.07760584918528221 0.12442979218551697 0.914219325233939 0.029246873850867248 0.03244219415971606 3.22062696729879e-07 6.492059574908843 -0.41043409948696064 (ac)SSDASQGVITT(ph)PPPPSMPHKER ddPTM_PC-9_Lapatinib_30min_R1 1 SSDASQGVITTPPPPSMPHKER 22 1 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 S(0.002)S(0.002)DAS(0.002)QGVIT(0.281)T(0.707)PPPPS(0.005)MPHKER 42.73 0.00038438 7026500.0 31291.0 8826.7 14175.0 11241.0 9271.9 12533.0 9254.9 7644.9 18310.0 9376.7 True False 30844.784601933385 8806.26231846083 13009.58621708235 12067.700638876726 8726.545071256762 11996.992805849957 9734.073437426507 8000.109963079569 16247.734987152216 10997.450101332613 2.8047214870468724 0.8007549238521876 1.1829638777361595 1.0973180626129346 0.7935062210647652 1.09088858738229 0.8851209460133839 0.7274513536651699 1.477409293740137 1.0 13.424881434880387 -4.757626015220443 24.999999834115197 0.9982339630024998 2.8047240698601827 0.866316765499013 0.21193622007484259 35.21946139269079 230861.90076683403 0.049908657954015764 0.3654644984344798 1.7473261833471002e-05 4.757626015220443 1.8064901068576829 (ac)SSEPPPPPQPPTHQASVGLLDT(ph)PRSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSEPPPPPQPPTHQASVGLLDTPRSR 26 1 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 1 SSEPPPPPQPPT(0.027)HQAS(0.114)VGLLDT(0.429)PRS(0.429)R;SSEPPPPPQPPT(0.006)HQAS(0.016)VGLLDT(0.577)PRS(0.402)R 51.025 0.0013502 23975800.0 732.71 0.0 0.0 512.51 659.77 721.82 383.07 616.61 591.69 619.04 True False 856.7433313178448 0.0 0.0 483.7957262798384 530.4928046985738 683.9664885085124 346.7828364133696 600.424640852299 600.3423468824958 731.2670516820559 1.1715874923492986 0.0 0.0 0.6615855659940024 0.7254433294626601 0.9353169774780047 0.4742218805232669 0.8210743796964542 0.8209618435585085 1.0 9.514254550507289 -5.980504254352463 23.575334491055038 0.7703953869606642 0.34802857618303595 0.22593101285117834 0.3309500321326727 173.95849366846937 210356.75857363033 0.09205041346166426 0.1365039697331123 1.045913444635925e-06 5.980504254352463 -0.4223668107776283 (ac)SSEPPPPPQPPTHQASVGLLDTPRS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 SSEPPPPPQPPTHQASVGLLDTPRSR 26 1 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 1 SSEPPPPPQPPT(0.005)HQAS(0.041)VGLLDT(0.127)PRS(0.827)R 55.413000000000004 6.6221e-05 18802000.0 1065.3 0.0 1874.2 3826.1 1524.1 2038.9 1369.0 1797.8 1640.7 2020.7 True False 1404.0432403834764 0.0 1849.3468834194753 2944.051757655732 1312.5050228809853 1911.4072606846173 1490.8383478955886 1519.991319334143 1727.4240524445643 1949.955908053212 0.7200384555285861 0.0 0.9484044617530956 1.509804270700152 0.6730947184294839 0.980231015886364 0.7645497735300102 0.7795003533447405 0.885878519257998 1.0 10.92922578712305 -5.28629669396126 24.579545719124397 0.9404132574339883 0.3600192610310787 0.43003632745931253 0.2683072729248741 491.95075819487414 486452.74528931646 0.06966974771512927 0.14513597605553702 5.172533428257258e-06 5.28629669396126 -0.5803939964029097 (ac)SSEPPPPPQPPTHQASVGLLDTPRS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSEPPPPPQPPTHQASVGLLDTPRSR 26 1 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 1 SSEPPPPPQPPT(0.001)HQAS(0.005)VGLLDT(0.033)PRS(0.961)R 50.341 0.00012964 14000000.0 1486.1 0.0 1899.5 2306.2 2366.1 2866.4 0.0 2041.2 0.0 1614.1 True False 1737.6673781870727 0.0 1944.791283893866 2176.9910908012785 1902.4796901909694 2716.0809379911902 0.0 1987.6206628301716 0.0 1906.7235527914308 0.9113368194582476 0.0 1.0199649975722511 1.1417444797459904 0.9977742643424904 1.424475474703643 0.0 1.0424272883818464 0.0 1.0 10.896879973657445 -11.633830454561949 3.4129075245711786 1.6161906449810843 0.7423398963915022 0.02499245261870031 0.5038822630071731 0.3262654824973755 0.0106067111601168 0.067377661752695 0.1162328652327345 2.323643753097788e-12 11.633830454561949 -0.8738507485895821 (ac)SSILPFT(ph)PPIVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSILPFTPPIVK 12 0 P84022 P84022 SMAD3 Mothers against decapentaplegic homolog 3 1 S(0.051)S(0.051)ILPFT(0.898)PPIVK 80.469 0.0046011 2878900.0 14513.0 18012.0 16375.0 19948.0 26112.0 17368.0 20554.0 13273.0 14859.0 13156.0 True False 16969.76425518402 19800.112322839013 16765.44210253332 18830.378232288575 20995.5410465604 16457.191505383405 18606.97632192653 12924.597813905979 15076.284764533793 15541.07865716131 1.0919296291808147 1.2740500681859137 1.0787823980807039 1.211651948213489 1.3509706442985976 1.0589478290684766 1.197277018693452 0.831640975444799 0.9700925590249593 1.0 13.9237990196742 -7.750278942506904 24.995981159796262 0.9256500775298739 1.1832781719455692 0.5903917608644143 0.09403408827782873 132.2875228848013 296285.36940929247 0.043441638534523985 0.02478369840121169 1.777137607709798e-08 7.750278942506904 0.25762809441569523 (ac)SSILPFT(ph)PPVVK ddPTM_PC-9_AZD4547_30min_R2 4 SSILPFTPPVVK 12 0 K7ESI8;K7EL92;K7ERC7;K7EJX0;B7Z5N5;Q15796-2;Q15796 K7ESI8 SMAD2 Mothers against decapentaplegic homolog;Mothers against decapentaplegic homolog 2 1 SSILPFT(1)PPVVK;S(0.008)S(0.008)ILPFT(0.984)PPVVK;SSILPFT(1)PPVVK;S(0.002)S(0.002)ILPFT(0.995)PPVVK 105.95 0.00039934 34172300.0 112994.0 123817.0 145311.0 160165.0 152208.0 152100.0 144146.0 177340.0 120538.0 143229.0 True False 148923.74157879493 163838.42387659784 143384.08119547914 123241.43377458265 131076.54650132445 142589.16295557926 156974.7147521967 149936.1778677919 126909.39259679591 138214.59630551495 1.0774820139083434 1.1853916174992327 1.0374018738117743 0.8916672845620803 0.9483553112696413 1.031650540297456 1.1357318181157485 1.0848071178847647 0.9182054282911656 1.0 17.076550455616058 -5.431556376986457 6.304300400825767 1.0064124729362054 1.1291933031879995 0.32659411993757215 0.07331985677803252 0.3005282282240852 17.095655659353 0.02113064405358732 0.04439415123904926 3.7020614478134427e-06 5.431556376986457 0.12278083025179409 (ac)SSILPFT(ph)PPVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSILPFTPPVVK 12 0 K7ESI8;K7EL92;K7ERC7;K7EJX0;B7Z5N5;Q15796-2;Q15796 K7ESI8 SMAD2 Mothers against decapentaplegic homolog;Mothers against decapentaplegic homolog 2 1 S(0.002)S(0.004)ILPFT(0.994)PPVVK;SSILPFT(1)PPVVK;S(0.184)S(0.184)ILPFT(0.632)PPVVK 117.03 0.00029976 16259100.0 100565.0 124972.0 126752.0 128165.0 146260.0 109919.0 118920.0 98584.0 105521.0 89174.0 True False 117588.66825071207 137378.39424882532 129774.24838963663 120984.3305665362 117601.40293619494 104154.65413865949 107655.03669375803 95996.27445838216 107064.04499888066 105340.54029900432 1.1162717403664533 1.304136032138083 1.2319497130096195 1.1485068352898864 1.11639263100786 0.9887423573395508 1.0219715637321027 0.9112946847044937 1.0163612669441817 1.0 16.68470123874414 -6.475062329306841 1.3799356569926349 0.97673715745933 1.2237737985752148 0.778928672431685 0.0538058018495643 0.17611922482300849 0.6879059948055735 0.0215712830333541 0.02504275468413092 3.3491736885903685e-07 6.475062329306841 0.24703664111588486 (ac)SSILPFT(ph)PPVVK ddPTM_PC-9_Lapatinib_30min_R1 1 SSILPFTPPVVK 12 0 K7ESI8;K7EL92;K7ERC7;K7EJX0;B7Z5N5;Q15796-2;Q15796 K7ESI8 SMAD2 Mothers against decapentaplegic homolog;Mothers against decapentaplegic homolog 2 1 S(0.088)S(0.309)ILPFT(0.604)PPVVK 96.756 0.005443899999999999 3750800.0 15308.0 28755.0 34382.0 27763.0 29807.0 30584.0 24881.0 27683.0 27394.0 22920.0 True False 15089.70511285662 28688.419564201933 31555.244678358056 29804.783634653024 28053.81086281672 29275.993614786174 26169.21643633199 28969.25324176008 24308.599248391492 26881.691461019716 0.5613376351238061 1.067210357867625 1.1738563670413118 1.108739146041907 1.0436028887355044 1.089068136104395 0.973495900519472 1.0776573819310244 0.9042808665384995 1.0 14.71433629838226 -4.760625186307691 24.999999815114307 1.0556298095775012 0.561337060981887 0.8057304035952659 0.07171288671899509 8.421141422022542 258416.82501631512 0.018151795766390574 0.10637180949950362 1.735300986573541e-05 4.760625186307691 -0.49429274859561423 (ac)SSS(ph)PVNVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSPVNVK 8 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1X7SBS1 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 1 S(0.218)S(0.218)S(0.564)PVNVK 73.039 0.037929000000000004 23259000.0 316450.0 352520.0 356140.0 382360.0 445630.0 326620.0 354030.0 336050.0 312570.0 262190.0 True False 370018.7348276014 387515.8558764819 364631.7282684721 360937.6088278448 358312.000481722 309491.47221835103 320493.715444763 327229.043574407 317140.74492565595 309722.971505102 1.194676433037858 1.251169243254204 1.177283449453363 1.1653562765262928 1.1568789965448836 0.9992525601648918 1.0347754119990535 1.0565217103020614 1.0239497037772407 1.0 18.24061886309184 -6.6393975554956945 3.807130688957086 1.0271482131255951 1.1962913816478509 0.9065232630327553 0.02683117570311352 0.0722693618390876 1.9747425096687365 0.010093526879603203 0.010036920053049304 2.2940477030919346e-07 6.6393975554956945 0.16914316852225575 (ac)SSSGTPDLPVLLTDLK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSGTPDLPVLLTDLK 16 0 P00352;Q5SYQ7;Q5SYQ9;Q5SYQ8 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ; 150.06 1.5720999999999997e-11 37672000.0 53165.0 64491.0 64846.0 58636.0 62805.0 50571.0 59296.0 52835.0 53959.0 62218.0 False True 52406.85735073306 64341.67505181521 59514.61219279873 62948.287043961915 59110.93337938082 48408.19621675882 62366.05674244374 55289.906983650406 47881.569206539956 72972.29839972618 0.7181746840925831 0.881727401532095 0.8155781508592589 0.862632648613383 0.8100462048705681 0.6633777101495335 0.8546538633169565 0.7576835072507169 0.6561609029258647 1.0 16.155061274417584 -4.68876445700757 21.542942803573844 0.8021734928986015 0.7181527336860036 0.06935242169124989 0.09730294020660839 35107.04584497786 10397421.65538243 0.023361220518516197 128.07451589428052 2.0475548429384178e-05 4.68876445700757 -0.08402075921259788 (ac)SSSSSSPRET(ph)YEEDREYESQAK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSSSSPRETYEEDREYESQAK 22 2 B7WPG3;V9GYK2;Q8WVV9-2;Q8WVV9-5;Q8WVV9 B7WPG3 HNRNPLL Heterogeneous nuclear ribonucleoprotein L-like 1 S(0.09)S(0.09)S(0.09)S(0.09)S(0.082)S(0.082)PRET(0.401)Y(0.074)EEDREY(0.001)ESQAK 43.598 0.00011029 5793900.0 7660.5 5619.3 9992.6 10204.0 7093.0 6533.7 5556.0 6197.2 9350.4 5105.9 True False 7551.259865236349 5606.288856098766 9171.04700055147 10954.436199546142 6675.803685374539 6254.268881798598 5843.6624942832095 6485.144535990884 8297.259487922893 5988.448011815905 1.2609710980769697 0.9361839403192455 1.5314563944541102 1.829261300746331 1.1147802689782729 1.0443889417522199 0.975822530771409 1.0829424457213186 1.3855442130500981 1.0 12.547966441971424 -6.478985656935759 24.997484677870546 1.0935566676333615 1.3803312984521263 0.2681057376839875 0.23372883978927741 701.9683586274085 399776.9408651832 0.07851229576824847 0.08901883012876527 3.3190541892175895e-07 6.478985656935759 0.28677463081876486 (ac)ST(ph)VHEILCK ddPTM_PC-9_Lapatinib_30min_R1 1 STVHEILCK 9 0 P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YNP5;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 S(0.179)T(0.821)VHEILCK 102.51 0.0024305999999999998 26460000.0 95314.0 104620.0 104750.0 94155.0 94297.0 79245.0 77402.0 60531.0 90215.0 68730.0 True False 93954.80488155289 104377.75881783357 96137.85934669334 101079.47279187242 88750.63585503509 75855.87607911744 81409.49682910526 63343.49123927966 80054.03669393435 80609.88892303169 1.165549365429138 1.2948505476480192 1.1926310857280569 1.2539339049131504 1.1009894324476293 0.9410244461637518 1.0099194765897404 0.7858029837972063 0.9931044163870754 1.0 16.298669213651188 -6.583439981160083 2.3156371203577453 0.9320271975485238 1.2303937935783362 0.787542041335465 0.06855343649844346 0.12375858766274785 1.3462497847564328 0.023948860759210756 0.02474698204215725 2.6095163293020794e-07 6.583439981160083 0.2983665960298124 (ac)STGPTAAT(ph)GSNRR ddPTM_PC-9_AZD4547_30min_R2 2 STGPTAATGSNRR 13 1 Q15836 Q15836 VAMP3 Vesicle-associated membrane protein 3 1 STGPTAAT(0.5)GS(0.5)NRR;STGPTAAT(0.5)GS(0.5)NRR 83.087 0.00053052 26050000.0 9099.8 7331.0 9297.5 15024.6 12401.599999999999 9507.7 7640.6 11470.8 11359.8 13122.900000000001 True False 11993.347112401723 9700.602384481428 9174.209075121418 11560.910597756023 10679.851907198232 8913.182015994476 8320.598598196519 9698.251432761199 11960.255836508664 12663.471265299888 0.9470821120955657 0.7660302756845798 0.7244624228950829 0.912933772703771 0.8433589561231036 0.7038498235802172 0.65705511734341 0.7658446273997631 0.9444689837360665 1.0 13.628385304914966 -8.370066295129583 4.014941474943391 0.9948329754657592 0.7857598404362313 0.4227841410283597 0.08589377126754809 0.22568406759267426 5.933105385384304 0.08705486350819897 0.02304685930420294 4.265144063323354e-09 8.370066295129583 -0.20907313502952796 (ac)STGPTAAT(ph)GSNRR ddPTM_PC-9_Lapatinib_30min_R1 1 STGPTAATGSNRR 13 1 Q15836 Q15836 VAMP3 Vesicle-associated membrane protein 3 1 STGPTAAT(0.566)GS(0.434)NRR 68.171 0.0045433999999999995 11930000.0 2665.9 3542.2 1850.8 2821.6 3253.0 2871.7 3031.3 4207.7 3027.4 2999.6 True False 2627.8837771338144 3533.9982535321205 1698.6343682946033 3029.109876581671 3061.6649356440694 2748.884085259659 3188.2458817351885 4403.2051029640525 2686.4223320647 3518.0768632842396 0.7469659928579842 1.0045255947685627 0.48283037418030506 0.8610129892824167 0.8702666412995608 0.7813598713399019 0.9062467949488906 1.2515943437499306 0.7636053549884175 1.0 11.780571287957356 -7.523760530396511 24.998647758346333 1.020344031000225 0.797796929484467 0.2520280678875255 0.16548356319004723 40.474150040573996 1147321.3277155075 0.0738165634797112 0.04308854578762908 2.9939150237223325e-08 7.523760530396511 -0.22254710151575796 (ac)STNENANT(ph)PAAR ddPTM_PC-9_AZD4547_30min_R2 2 STNENANTPAAR 12 0 P52292;J3QLL0;J3KS65;J3QL07 P52292 KPNA2 Importin subunit alpha-1 1 STNENANT(1)PAAR;STNENANT(1)PAAR 169.89 4.5151999999999996e-10 31528000.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)STNENANT(ph)PAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STNENANTPAAR 12 0 P52292;J3QLL0;J3KS65;J3QL07 P52292 KPNA2 Importin subunit alpha-1 1 STNENANT(1)PAAR;STNENANT(1)PAAR 189.24 1.1625e-38 28306000.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)STNENANT(ph)PAAR ddPTM_PC-9_Lapatinib_30min_R1 2 STNENANTPAAR 12 0 P52292;J3QLL0;J3KS65;J3QL07 P52292 KPNA2 Importin subunit alpha-1 1 STNENANT(1)PAAR;STNENANT(1)PAAR 171.32 6.305e-21 27245000.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 (ac)STSS(ph)LRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STSSLRR 7 1 Q9Y6I3-3;Q9Y6I3 Q9Y6I3-3 EPN1 Epsin-1 1 ST(0.001)S(0.023)S(0.976)LRR;STS(0.025)S(0.974)LRR 53.968 0.018583000000000002 8829600.0 0.0 3816.58 1026.5 703.35 1308.51 682.81 590.54 641.81 473.14 0.0 True False 0.0 4195.46483950149 1050.9756530229288 663.9435797914664 1052.11685871763 647.0022415816924 534.5997760606451 624.9631675539058 480.0587774070607 0.0 0.0 (ac)STSS(ph)LRR ddPTM_PC-9_Lapatinib_30min_R1 1 STSSLRR 7 1 Q9Y6I3-3;Q9Y6I3 Q9Y6I3-3 EPN1 Epsin-1 1 ST(0.004)S(0.038)S(0.958)LRR 49.423 0.03178 1929200.0 434.11 1097.2 0.0 0.0 0.0 419.95 0.0 0.0 0.0 0.0 True False 427.919511793976 1094.659500811767 0.0 0.0 0.0 401.9897174512635 0.0 0.0 0.0 0.0 0.0 (ac)STVHEILCK ddPTM_PC-9_AZD4547_30min_R2 1 STVHEILCK 9 0 P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YNP5;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 54.776 0.00052552 5038900.0 36559.0 41224.0 82543.0 132060.0 102040.0 85790.0 71487.0 108010.0 82311.0 101580.0 False True 48184.001525560445 54548.85182074242 81448.42588736187 101615.60730666103 87873.50733861003 80425.53773806155 77849.20451133087 91319.53632288406 86661.79141876298 98023.71511854551 0.49155453317892367 0.5564862722737398 0.8309053149930277 1.0366430938041027 0.8964515090286032 0.8204702060190077 0.7941874516506899 0.9316065628857902 0.88409005222826 1.0 16.580843205765923 -5.272717616905687 3.3949223517488343 0.8993993842578044 0.506604399685497 0.8261349707747713 0.06973078949711348 0.09394722716527114 2.2866060668789827 0.01955859487449707 0.05332163798526639 5.336817885231703e-06 5.272717616905687 -0.39279498457230744 (ac)STVHEILCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STVHEILCK 9 0 P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YNP5;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ; 60.973 0.0018413 14091400.0 88797.0 93001.0 126096.0 153660.0 188375.0 152329.0 128921.0 134618.0 133088.0 100113.0 False True 103828.57827930647 102233.52465780302 129102.60686174288 145050.92837244144 151464.27101125193 144340.59908012144 116708.66957278829 131084.4201395613 135034.16022224075 118262.69440592831 0.8779486954941365 0.8644613178429176 1.091659610076254 1.2265146595981014 1.2807442936431126 1.2205082913524916 0.986859551602926 1.1084173314166454 1.1418153535276778 1.0 16.851635526276468 -5.323048238457833 3.982162685680707 1.1460376829681596 0.8677616818677399 0.5811783066720367 0.08888295375109953 0.15243019839650848 4.844097149026378 0.025507044569091954 0.0601203811777481 4.752824318921479e-06 5.323048238457833 -0.2782760011004196 (ac)STVHEILCK ddPTM_PC-9_Lapatinib_30min_R1 4 STVHEILCK 9 0 P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YNP5;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ;;; 75.109 0.00045963 99874900.0 263019.0 287429.0 310195.0 319490.0 345359.0 356076.0 346903.0 273922.0 368989.0 256436.0 False True 259268.30082822224 286763.47581008484 284691.96448732744 342986.3603873972 325045.6626219182 340847.45953369694 364863.93993058446 286649.41612142464 327429.57319357275 300760.6209205084 0.8620420453804933 0.9534608451479324 0.9465732701841045 1.1403965031647183 1.0807454168271198 1.1332848645228177 1.213137340965321 0.9530816077055069 1.0886716891042494 1.0 18.198256159398575 -5.665575154541974 5.376665718777751 1.091737330841362 0.9183410434365009 0.5327127343526026 0.0716123375667168 0.16143643286768866 7.269342396549927 0.01987456476659999 0.034839529496917085 2.159856239898246e-06 5.665575154541974 -0.17339628740486113 (ac)SVCTLSVPVSS(ph)LSPGRR ddPTM_PC-9_Lapatinib_30min_R1 1 SVCTLSVPVSSLSPGRR 17 1 P86452 P86452 ZBED6 Zinc finger BED domain-containing protein 6 1 SVCTLSVPVS(0.043)S(0.777)LS(0.18)PGRR 91.932 0.00016414 1858600.0 770.18 1240.4 1474.6 813.42 925.57 1279.0 928.33 1044.0 1543.2 1197.7 True False 759.1970919662859 1237.5279300099487 1353.364080120609 873.2416202895745 871.1297923406333 1224.3001514946218 976.3943850464249 1092.508051309379 1369.3885653835785 1404.7208491650663 0.5404611830297352 0.8809778332438839 0.9634398755631893 0.621647796292487 0.6201444172046089 0.8715611733265849 0.6950807241358816 0.7777403261001932 0.9748474696574138 1.0 10.456067746397649 -8.258231993130659 3.8819964101089184 0.9982736747332124 0.7504693701669354 0.372756029720254 0.1256471036413798 0.2450114563391023 8.166337917972042 0.11130099689339729 0.032968044433225124 5.517826071420124e-09 8.258231993130659 -0.247804304566277 (ac)SYGRPPPDVEGMTSLK ddPTM_PC-9_Lapatinib_30min_R1 1 SYGRPPPDVEGMTSLK 16 1 J3QL05;J3KP15;Q01130-2;Q01130 J3QL05 SRSF2 Serine/arginine-rich splicing factor 2 0 63.091 0.003795 0.0 7992.5 5079.3 7158.9 6313.0 7849.2 8908.0 5398.0 4370.9 5453.0 6211.8 False True 7878.525484355007 5067.539192921259 6570.322876153142 6777.279079550647 7387.5254881209485 8527.025605562225 5677.482027383149 4573.987970754947 4838.825717364339 7285.501353296784 1.081397847903751 0.6955649236998812 0.9018353792742053 0.9302419628930327 1.014003721895954 1.1704102699402608 0.7792850144505175 0.6278206191925498 0.6641719605438968 1.0 12.83081253972846 -7.501236472550935 24.601516739813906 0.7283083111587235 0.9529876680088992 0.2841146126001516 0.14997090900810875 737.5606217768042 838413.8601428454 0.06398830702489483 0.04266085959890032 3.153287196738959e-08 7.501236472550935 0.2246793568501757 (ac)T(ph)TPGKENFR ddPTM_PC-9_AZD4547_30min_R2 1 TTPGKENFR 9 1 C9J352;C9JWD9;F2Z3G4;C9J4U1;C9JYI4;P52294 C9J352 KPNA1 Importin subunit alpha-5;Importin subunit alpha-5, N-terminally processed 1 T(0.5)T(0.5)PGKENFR 45.972 0.028831 18396000.0 90813.0 100460.0 99059.0 141180.0 147340.0 133240.0 115190.0 149400.0 122630.0 128920.0 True False 119689.64497225647 132931.7303976272 97745.41293599932 108633.13220925642 126884.38427352821 124908.48173702383 125441.68684740183 126313.66287046435 129111.97144589327 124406.55004019408 0.9620847530422342 1.068526780580916 0.785693461513233 0.8732107125722763 1.019917232915257 1.004034608279609 1.0083205973228364 1.0153296818347113 1.0378229394206249 1.0 16.924702920208674 -6.280630504541688 23.913385913021507 1.0141980160850097 0.9230548123779967 0.3104828990419478 0.06705934530462018 637.1266345859173 793898.4576373671 0.02225457118437733 0.025278663146129293 5.240461026383247e-07 6.280630504541688 -0.09114320370701301 (ac)T(ph)TPGKENFR ddPTM_PC-9_Lapatinib_30min_R1 2 TTPGKENFR 9 1 C9J352;C9JWD9;F2Z3G4;C9J4U1;C9JYI4;P52294 C9J352 KPNA1 Importin subunit alpha-5;Importin subunit alpha-5, N-terminally processed 1 T(0.5)T(0.5)PGKENFR;T(0.5)T(0.5)PGKENFR 47.574 0.014878 38088000.0 454200.0 427380.0 452730.0 428640.0 400200.0 393280.0 338260.0 292050.0 416700.0 284860.0 True False 447723.02470992156 426390.42786814924 415508.28698833863 460163.61550112197 376661.02282347286 376460.3311804571 355773.4476811083 305619.70918094274 369766.8579544696 334097.67144790833 1.3400962142884298 1.2762448358896479 1.2436731007061916 1.377332603088404 1.1273979288484832 1.1267972313274677 1.0648785612281038 0.9147615661505566 1.1067627510002647 1.0 18.349910402029593 -6.698789618378114 1.3324012571127815 1.012925018563892 1.304899464818699 0.7912508687862871 0.06460166829942517 0.18313437389851986 0.681401845711127 0.02908033888388808 0.027769800240450233 2.0008308805781633e-07 6.698789618378114 0.29197444625480684 (ac)TECFLPPTS(ph)SPSEHR ddPTM_PC-9_AZD4547_30min_R2 1 TECFLPPTSSPSEHR 15 0 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 TECFLPPT(0.004)S(0.557)S(0.381)PS(0.058)EHR 106.55 0.00015031 12999000.0 0.0 809.57 1335.6 1051.2 1195.0 1422.3 1055.1 880.5 1384.7 1771.8 True False 0.0 1071.2476704957887 1317.8890713344624 808.8620808781028 1029.0948772014813 1333.3633561585816 1149.0018560004637 744.4389568771345 1457.8924150789226 1709.769821293947 0.0 0.6265449636285385 0.7707991186422329 0.47308244115921944 0.6018908886944012 0.77984962627864 0.6720213690114752 0.43540302770916034 0.8526834413158582 1.0 10.739586399229513 -5.964559419153232 0.13806934492688097 1.0941193578641175 8.563181867200008e-23 0.4280196071328328 0.19865589585776566 22.546157195439083 0.8558994853374856 1.6825562123057924 5.317957303165694 1.0850270886134977e-06 5.964559419153232 -1.0941193578641175 (ac)TECFLPPTS(ph)SPSEHRR ddPTM_PC-9_Lapatinib_30min_R1 1 TECFLPPTSSPSEHRR 16 1 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 TECFLPPT(0.142)S(0.415)S(0.415)PS(0.028)EHRR 52.731 0.010466 8636600.0 7286.6 10201.0 9078.3 5849.0 7077.7 6510.3 9811.5 5650.2 11005.0 6649.1 True False 7182.6917478012165 10177.380211247571 8331.917217251403 6279.154971692022 6661.403601293586 6231.869645250534 10319.491461961798 5912.728919069209 9765.501012212466 7798.3880756311555 0.921048257427211 1.3050620349416087 1.068415310503391 0.8051862655198554 0.8542026296574694 0.7991227911219542 1.3232851920012456 0.7581988561899913 1.2522460946420781 1.0 12.928960234839755 -5.532163225613938 24.927582581018278 0.9609667734385463 1.1314760463724032 0.08003337755495066 0.19875318208183307 384.8137716498082 1033169.765908646 0.05188995575853004 0.09003190840815065 2.936545770628806e-06 5.532163225613938 0.17050927293385687 (ac)TECFLPPTSS(ph)PSEHR ddPTM_PC-9_AZD4547_30min_R2 1 TECFLPPTSSPSEHR 15 0 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 TECFLPPT(0.006)S(0.179)S(0.725)PS(0.09)EHR 124.16 0.00029243 13045000.0 0.0 0.0 1245.5 1085.2 3272.0 661.13 628.77 1637.8 1349.1 1287.8 True False 0.0 0.0 1228.9838562047566 835.0239061728663 2817.7392788311686 619.7894365866014 684.7293119111093 1384.7156428999099 1420.410671757763 1242.714513975813 0.0 0.0 0.9889510763601467 0.6719354258617104 2.267406751222679 0.4987383905284174 0.5509948618210444 1.114266895032708 1.1429903294630779 1.0 10.279279192012567 -5.269734522086571 5.572678185401828 1.0319680041306922 1.5074956415956027e-14 0.43619039042940877 0.4682590826975013 0.1457980353370556 17.415491840872374 0.12483700370138924 0.2952136408814641 5.3736017646965285e-06 5.269734522086571 -1.0319680041306771 (ac)TECFLPPTSS(ph)PSEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TECFLPPTSSPSEHR 15 0 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 TECFLPPT(0.007)S(0.078)S(0.621)PS(0.295)EHR;TECFLPPT(0.001)S(0.03)S(0.848)PS(0.121)EHR;TECFLPPT(0.007)S(0.024)S(0.789)PS(0.18)EHR 103.88 3.6225e-05 19548000.0 3324.5 8402.5 15813.7 8625.599999999999 22704.6 10179.699999999999 10290.199999999999 9675.7 14504.599999999999 6318.4 True False 3887.272188131968 9236.644669812053 16190.758581791226 8142.33559657251 18255.796616334836 9645.858611662328 9315.437761403542 9421.723127251571 14716.702334992715 7463.875903573119 0.5208114709237123 1.2375131619471689 2.1692159396755724 1.0908991121723497 2.4458869429481527 1.2923390924874094 1.2480697538049956 1.2623097233893168 1.9717238771276342 1.0 12.865709284411784 -4.850891565154281 3.737503846475214 1.5707577160355337 0.48224267794748976 0.3158033383779545 0.4616785599935502 0.26892675274596745 6.301553692943989 0.11132814061496657 0.7041548203566519 1.4096407142277907e-05 4.850891565154281 -1.088515038088044 (ac)TECFLPPTSS(ph)PSEHR ddPTM_PC-9_Lapatinib_30min_R1 1 TECFLPPTSSPSEHR 15 0 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 TECFLPPT(0.004)S(0.16)S(0.752)PS(0.084)EHR 130.47 0.00046688 9048300.0 568.03 1736.7 1146.0 757.83 1041.8 0.0 710.84 1209.6 875.19 729.0 True False 559.9297880360558 1732.678777852529 1051.7803036879282 813.5633462467705 980.5233722576063 0.0 747.643817033168 1265.8024318619007 776.6168860407299 855.0066786685586 0.6548835254807539 2.026509056690302 1.2301427929496307 0.9515286447980443 1.1468020036808437 0.0 0.8744303824590246 1.480459116217718 0.9083167481803773 1.0 9.73979187906493 -5.6990695189733405 3.733569035521197 0.895768256436039 1.3995152093959389 0.12933437320947927 0.466290643676032 0.4051685887685018 11.286568220115335 0.13314309714891853 0.2364421277923542 1.999541770660688e-06 5.6990695189733405 0.5037469529598999 (ac)TECFLPPTSS(ph)PSEHRR ddPTM_PC-9_AZD4547_30min_R2 2 TECFLPPTSSPSEHRR 16 1 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 TECFLPPT(0.008)S(0.187)S(0.765)PS(0.04)EHRR;T(0.003)ECFLPPT(0.337)S(0.268)S(0.385)PS(0.006)EHRR 72.676 0.0041656 19587200.0 9848.1 7126.9 12222.0 15042.5 11592.5 11545.1 13375.5 14987.9 5803.9 12148.5 True False 12979.59094679482 9430.531050874466 12059.928294287069 11574.684029308266 9983.081476115625 10823.183071916217 14565.893588223114 12671.864442678936 6110.682305103309 11723.18471271562 1.107172774708261 0.8044342285800195 1.0287245820844397 0.9873327353405699 0.8515673616647376 0.923228912377094 1.2424860603300172 1.0809233798845057 0.5212476349089102 1.0 13.517076924148016 -8.233998370274827 24.9774910961873 0.7606235670172069 0.9971794711389094 0.2661921108860196 0.16087362157840263 843.4226698100183 767706.895952227 0.1068945158068925 0.04038158806345058 5.834472937028003e-09 8.233998370274827 0.23655590412170246 (ac)TECFLPPTSS(ph)PSEHRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TECFLPPTSSPSEHRR 16 1 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 TECFLPPT(0.041)S(0.041)S(0.648)PS(0.271)EHRR 75.316 0.0047958 0.0 926.55 1102.2 1574.7 1291.5 0.0 886.95 1295.1 1135.9 1171.5 0.0 True False 1083.3966148033323 1211.6191318139652 1612.2468200830056 1219.1414420994936 0.0 840.4367806137617 1172.4187522879768 1106.0838285855336 1188.630971239743 0.0 0.0 (ac)TECFLPPTSS(ph)PSEHRR ddPTM_PC-9_Lapatinib_30min_R1 1 TECFLPPTSSPSEHRR 16 1 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 TECFLPPT(0.056)S(0.056)S(0.831)PS(0.057)EHRR 58.511 0.0011124000000000002 5891900.0 1232.2 1241.0 3305.1 835.85 1093.9 2772.7 998.08 2313.0 2588.2 896.85 True False 1214.6286020421946 1238.1265407468127 3033.367436054946 897.3211973138616 1029.558952690147 2654.118084479387 1049.755698757054 2420.4704240216415 2296.6896610457334 1051.8693275224925 1.1547333592310893 1.177072577696527 2.883787326701075 0.8530728806660387 0.9787897847683286 2.5232393559100457 0.9979905975864731 2.30111322831579 2.1834362890447743 1.0 10.038739776132001 -6.738554801109986 24.9997343065829 1.8322784051111438 1.447572559549151 0.06909260558374775 0.7073962925135622 744.7046354278364 813533.7834640677 0.23325949696189643 0.23311054045975094 1.8257663516379765e-07 6.738554801109986 -0.3847058455619927 (ac)TECFLPPTSSPS(ph)EHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TECFLPPTSSPSEHR 15 0 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 TECFLPPT(0.027)S(0.298)S(0.298)PS(0.376)EHR 52.00899999999999 0.020915 9429800.0 1790.9 1410.7 2118.5 2383.4 2104.8 1132.7 2018.3 4113.9 1458.7 1373.0 True False 2094.0639981126624 1550.7449730084936 2169.01307445599 2249.8658250870576 1692.3795494332235 1073.2992179956118 1827.1120127733932 4005.9144840373506 1480.0307279107246 1621.9140313379796 1.2911066540223393 0.9561203263832819 1.3373169184970226 1.3871671257637843 1.0434459020230031 0.6617485250498794 1.1265159419492399 2.4698685667900144 0.9125210703614113 1.0 10.663481636985898 -7.576288017282036 24.99999325225973 1.5743553890714486 1.1059501388832051 0.09784726832220292 0.44276630257884747 156.99953636169437 73486.95270739422 0.19878437711746869 0.11476820829451677 2.6528456528803133e-08 7.576288017282036 -0.4684052501882434 (ac)TECFLPPTSSPS(ph)EHRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TECFLPPTSSPSEHRR 16 1 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 TECFLPPT(0.075)S(0.075)S(0.217)PS(0.633)EHRR 74.783 0.00036492 5208600.0 0.0 1733.6 1982.9 1029.3 1617.9 1213.3 776.78 0.0 1055.7 0.0 True False 0.0 1905.7003510367351 2030.1798561901264 971.6316580356241 1300.884109192329 1149.6724121074203 703.1977749998099 0.0 1071.137615311819 0.0 0.0 (ac)TECFLPPTSSPS(ph)EHRR ddPTM_PC-9_Lapatinib_30min_R1 1 TECFLPPTSSPSEHRR 16 1 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 T(0.001)ECFLPPT(0.252)S(0.252)S(0.125)PS(0.369)EHRR 54.858999999999995 0.0058858 4207600.0 555.01 872.84 616.78 671.02 3042.7 892.94 587.78 867.79 1165.4 681.89 True False 547.0954556236314 870.8189926071298 566.070729239651 720.3690492571001 2863.734368178363 854.7510377448062 618.2123723703718 908.1106914231475 1034.1403797939495 799.7537779386886 0.6840798639723004 1.0888588671023312 0.7078062584445178 0.9007385386960005 3.58077004094866 1.0687677399259925 0.7730033785695548 1.1354878419752408 1.2930734537564506 1.0 9.643412092246074 -6.0412552146936855 24.998852017346312 1.5005485994503347 0.8449656675710282 0.14577630450147905 0.746600498050817 1026.4190972774616 621963.1588556438 0.2318166095029989 0.2993090803459818 9.093787159505802e-07 6.0412552146936855 -0.6555829318793065 (ac)TEKAPEPHVEEDDDDELDSK ddPTM_PC-9_AZD4547_30min_R2 1 TEKAPEPHVEEDDDDELDSK 20 1 F5H3P3;P52566;F5H2R5;F5H6Q0 F5H3P3 ARHGDIB Rho GDP-dissociation inhibitor 2 0 64.331 4.596600000000001e-05 3667900.0 16604.0 16299.0 18217.0 20257.0 21342.0 20628.0 14547.0 18514.0 21686.0 21367.0 False True 21883.7266153452 21567.333005683104 17975.430677223652 15587.061617530166 18379.03168973556 19338.127899064348 15841.65481872689 15653.086709396113 22832.27768715354 20618.947833608632 1.061340607287196 1.0459958083083472 0.8717918500149615 0.7559581479770489 0.8913661277991093 0.9378814115598778 0.7683056840031958 0.7591603041878681 1.1073444615800039 1.0 14.33168309470143 -5.254165779037413 6.38312572445352 0.870773731140507 1.0552833669341022 0.2733200537255116 0.10667753037326096 0.16492939279328744 34.776689485286134 0.027055437787500254 0.0661142101562939 5.569731003869693e-06 5.254165779037413 0.18450963579359514 (ac)TTSS(ph)IRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTSSIRR 7 1 F6PQP6;E9PBC1;I3L2B2;O95208-2;O95208;J3KSR0;J3QKL8;J3KSF8;J3KTF6;J3KSA6;J3KSC7;J3QLN2 F6PQP6 EPN2 Epsin-2 1 TTS(0.027)S(0.973)IRR 57.047 0.037587 686380.0 0.0 593.0 0.0 0.0 0.0 731.66 0.0 0.0 0.0 459.03 True False 0.0 651.8691209995297 0.0 0.0 0.0 693.2904615861829 0.0 0.0 0.0 542.2485053205195 0.0 1.2021593690040957 0.0 0.0 0.0 1.2785474829043255 0.0 0.0 0.0 1.0 9.082810360964766 -11.244523515152638 5.172559298943599 1.0257227640940552 0.2918478649304028 0.16381237527527115 0.48974170788384364 0.13812481629850404 0.007433018212943828 0.45085045044299477 0.11544266693891321 5.6947738857550635e-12 11.244523515152638 -0.7338748991636523 (ac)YMLS(ph)S(ph)TVS(ph)SKILR ddPTM_PC-9_Lapatinib_30min_R1 1 YMLSSTVSSKILR 13 1 H0Y921 H0Y921 PGM2 3 Y(0.452)MLS(0.547)S(0.503)T(0.503)VS(0.818)S(0.178)KILR 42.083 0.042879 5069800.0 14730.0 32847.0 11425.0 21586.0 20804.0 16024.0 27855.0 20169.0 12095.0 18322.0 True False 14519.947498848835 32770.94478961367 10485.680601775364 23173.506448785076 19580.349622237707 15338.690873768423 29297.195604438246 21106.125370554466 10732.73373400362 21488.93328746959 0.6756941959196997 1.5250149624096387 0.4879572411297711 1.0783925911435435 0.9111829498607641 0.7137948947290261 1.3633620251183771 0.9821858110966195 0.4994540022264382 1.0 14.391306248584405 -5.263873819655675 24.999714897932098 0.8984966894911233 1.1003545352693713 0.07064371469759745 0.3144034807412049 597.3766993251611 6134648.588643476 0.07825421946586293 0.1761893103807781 5.446608761607865e-06 5.263873819655675 0.20185784577824806 AAAAAAAAAAAATGTEAGPGTAGGSENGSEVAAQPAGLS(ph)GPAEVGPGAVGERTPR ddPTM_PC-9_AZD4547_30min_R2 1 AAAAAAAAAAAATGTEAGPGTAGGSENGSEVAAQPAGLSGPAEVGPGAVGERTPR 55 1 R4GMQ1;O60341;O60341-2 R4GMQ1 KDM1A Lysine-specific histone demethylase 1A 1 AAAAAAAAAAAATGTEAGPGT(0.002)AGGS(0.011)ENGS(0.065)EVAAQPAGLS(0.509)GPAEVGPGAVGERT(0.414)PR 115.82 2.2239e-51 7892200.0 23389.0 22355.0 35293.0 46261.0 40975.0 37123.0 28690.0 43654.0 32096.0 43264.0 True False 30826.215478577993 29580.816574148474 34824.99175996345 35596.24117532526 35286.32852998384 34801.69294148562 31243.354420105505 36908.27736912486 33792.52903471735 41749.34052853669 0.738364129548526 0.7085337444774551 0.8341447150802231 0.8526180467687714 0.845194872140909 0.8335866507327898 0.7483556392645271 0.8840445597912415 0.8094146783377173 1.0 15.349465788543949 -14.52287874528033 0.10975161186771674 1.5898809597821306 0.7018406702797416 0.6115372680002052 0.04932282156686578 125.1600141129987 0.9103937391977056 16.759675089604873 0.6674704585968511 3.0000000000000503e-15 14.52287874528033 -0.888040289502389 AAAAAAAAAAAATGTEAGPGTAGGSENGSEVAAQPAGLS(ph)GPAEVGPGAVGERTPR ddPTM_PC-9_Lapatinib_30min_R1 2 AAAAAAAAAAAATGTEAGPGTAGGSENGSEVAAQPAGLSGPAEVGPGAVGERTPR 55 1 R4GMQ1;O60341;O60341-2 R4GMQ1 KDM1A Lysine-specific histone demethylase 1A 1 AAAAAAAAAAAATGTEAGPGT(0.006)AGGS(0.006)ENGS(0.01)EVAAQPAGLS(0.754)GPAEVGPGAVGERT(0.224)PR;AAAAAAAAAAAATGTEAGPGT(0.058)AGGS(0.115)ENGS(0.115)EVAAQPAGLS(0.392)GPAEVGPGAVGERT(0.32)PR 91.262 2.5981e-26 12155000.0 79498.0 65462.0 82796.0 68663.0 72518.0 62405.0 45521.0 43600.0 82864.0 55011.0 True False 78364.34394185228 65310.426760973285 75988.8324818024 73712.7060730534 68252.63381587359 59736.08362316017 47877.854644036364 45625.81516962537 73530.983723396 64519.57805245006 1.2145823997507759 1.0122574996984686 1.177763940427952 1.1424858670515474 1.057859271187248 0.9258597998672399 0.7420670762154535 0.7071623303632684 1.139669321203872 1.0 15.977449383082863 -6.720750242791691 2.8255384974457445 0.8690904784723635 1.1282185801218383 0.43254702971232506 0.12544119165968215 0.23489641400124867 3.8353063013164785 0.04555202793602167 0.04332227448527474 1.902171880182904e-07 6.720750242791691 0.25912810164947475 AAAAAAGSGT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 AAAAAAGSGTPR 12 0 Q9NR33 Q9NR33 POLE4 DNA polymerase epsilon subunit 4 1 AAAAAAGS(0.193)GT(0.807)PR;AAAAAAGS(0.111)GT(0.889)PR 105.36 0.0044020000000000005 15465500.0 31091.0 36484.0 40891.0 49040.0 32616.0 39961.0 29229.0 41692.0 31508.0 28623.0 True False 40977.29126702588 48276.739516494396 40348.75862229522 37734.58566044722 28087.831393140994 37462.23235284614 31830.32437592415 35249.45938685009 33173.44855514312 27620.917482163157 1.483560105977215 1.7478325818709755 1.46080443013348 1.366159747764179 1.0169043592154154 1.3562993472985914 1.1523992422221063 1.2761871291789362 1.2010263082884787 1.0 14.753473621845735 -5.7884666865041075 2.27266375938079 1.1902274782784006 1.610191033508052 0.676752297752143 0.12320215426638186 0.16349782614146507 1.7234173302460745 0.03466815322277002 0.06371661240071969 1.627546155295901e-06 5.7884666865041075 0.41996355522965145 AAAAAAGSGT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AAAAAAGSGTPR 12 0 Q9NR33 Q9NR33 POLE4 DNA polymerase epsilon subunit 4 1 AAAAAAGS(0.107)GT(0.893)PR;AAAAAAGS(0.3)GT(0.7)PR 105.46 0.0043723 12746100.0 23574.6 27027.5 30419.3 24911.3 36589.0 20667.9 28810.0 14817.8 21978.3 24613.0 True False 27565.31416042591 29710.611581475205 31144.611477837672 23515.600624524286 29419.64810633421 19584.038940241462 26080.90823366274 14428.848450756876 22299.691058641434 29075.14206359919 0.9480715210308975 1.0218561105044985 1.071176588224804 0.8087871272678937 1.0118488171779676 0.6735664058804316 0.897017396393564 0.49626063457214076 0.7669675700934812 1.0 14.827498620394953 -6.583552578159604 1.3220173480690134 0.7376375742015883 0.994400816542512 0.28101463911088764 0.1468673770987578 0.4704848122429177 1.7136129213669529 0.06206712683724306 0.0657565036087055 2.608839862905585e-07 6.583552578159604 0.25676324234092374 AAAAAAGSGT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 AAAAAAGSGTPR 12 0 Q9NR33 Q9NR33 POLE4 DNA polymerase epsilon subunit 4 1 AAAAAAGS(0.118)GT(0.882)PR;AAAAAAGS(0.112)GT(0.888)PR;AAAAAAGS(0.045)GT(0.955)PR 92.943 0.013659000000000001 13559500.0 45824.0 85621.0 54537.0 46361.6 61262.0 48780.2 55473.0 49818.0 58949.0 34168.0 True False 45170.54135690759 85422.74983503866 50053.17837890795 49771.186721763865 57658.68960572609 46693.98455820008 58345.120508526365 52132.72614955042 52309.54285951045 40073.89327400183 1.1271812560875447 2.131630916191943 1.2490221011638079 1.2419853090254451 1.4388092819305007 1.165197108225396 1.4559384113142333 1.300914932150399 1.3053271989783577 1.0 15.290375057380135 -4.433363163809776 0.04119761871585443 3.774526074781981e-08 3.0749456759990355 0.17974079027212686 0.26589437482362804 631.7031475969818 3.6889772170323107 97.57425018876538 189.07269569439865 3.6866918272454694e-05 4.433363163809776 3.0749456382537748 AAAAAATAPPS(ph)PGPAQPGPR ddPTM_PC-9_AZD4547_30min_R2 3 AAAAAATAPPSPGPAQPGPR 20 0 Q6SPF0 Q6SPF0 SAMD1 Atherin 1 AAAAAAT(0.003)APPS(0.997)PGPAQPGPR;AAAAAAT(0.056)APPS(0.944)PGPAQPGPR;AAAAAATAPPS(1)PGPAQPGPR 229.22 3.8336e-36 155115400.0 102617.0 90334.0 151347.0 194195.0 173364.0 140963.0 104349.0 166537.0 124602.0 133624.0 True False 135247.07143380353 119532.69892234981 149340.03989162692 149426.34303284172 149295.40108046625 132148.56132614898 113635.85884920137 140802.53328954813 131188.20733997523 128945.86443198046 1.0488670732448886 0.9269990894931249 1.158160756449886 1.15883005392286 1.157814573876623 1.0248375309148279 0.8812679596183932 1.0919507493303293 1.0173898008894857 1.0 16.976405978008692 -6.984425509830188 24.117104134317657 0.9978486979760827 1.0889328678584689 0.2307781223466897 0.0806742651077055 262.84358855763725 407010.7738052279 0.030722097874108015 0.027084304342073085 1.036512371740213e-07 6.984425509830188 0.09108416988238621 AAAAAATAPPS(ph)PGPAQPGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 AAAAAATAPPSPGPAQPGPR 20 0 Q6SPF0 Q6SPF0 SAMD1 Atherin 1 AAAAAAT(0.002)APPS(0.998)PGPAQPGPR;AAAAAAT(0.003)APPS(0.997)PGPAQPGPR;AAAAAAT(0.005)APPS(0.995)PGPAQPGPR;AAAAAAT(0.029)APPS(0.971)PGPAQPGPR;AAAAAATAPPS(1)PGPAQPGPR;AAAAAAT(0.245)APPS(0.755)PGPAQPGPR 249.49 1.0314999999999999e-54 119263300.0 276444.0 275675.0 348629.0 348326.0 394495.0 365436.0 373022.0 366637.0 359088.0 273710.0 True False 323240.5091821193 303042.19212739595 356941.6375428457 328810.42350812926 317196.5366560529 346271.8928466885 337686.6557145902 357013.1672340122 364338.9826722466 323331.456312832 0.9997187185813905 0.9372493341142606 1.10394961756364 1.0169453577383951 0.9810259115313439 1.0709502155944302 1.0443977816617669 1.1041708446968803 1.1268281373765832 1.0 18.302654345831826 -6.791447512175421 15.741941790502189 1.0742303884941555 1.0097131861077036 0.26995591449171963 0.050180191961276335 5.221468007435893 2737.3237338127283 0.01796112854442234 0.015866453314765147 1.6164135702999218e-07 6.791447512175421 -0.06451720238645198 AAAAAATAPPS(ph)PGPAQPGPR ddPTM_PC-9_Lapatinib_30min_R1 4 AAAAAATAPPSPGPAQPGPR 20 0 Q6SPF0 Q6SPF0 SAMD1 Atherin 1 AAAAAAT(0.012)APPS(0.988)PGPAQPGPR;AAAAAAT(0.354)APPS(0.646)PGPAQPGPR;AAAAAAT(0.13)APPS(0.87)PGPAQPGPR;AAAAAATAPPS(1)PGPAQPGPR 199.31 9.6753e-16 142667200.0 200824.0 178227.6 204263.0 174154.0 204337.0 202903.0 173104.0 172469.0 215993.0 164772.0 True False 197960.21293338845 177814.92494247103 187469.28461798222 186961.86612071315 192318.29940199872 194225.3116799949 182066.4781156228 180482.53936903938 191665.5938328765 193252.62065511057 1.024359784940145 0.920116500048967 0.9700736992982382 0.9674480246991101 0.9951652854696378 1.0050332617564872 0.9421164768603517 0.9339202684921857 0.9917878121556428 1.0 17.560128452780965 -4.239817577670492 6.833748094609433 0.9686016108376737 5.820638439759662 0.2564434891638634 0.02796054344288889 4960.5384449936255 1573.630662946098 0.007132013044946864 369456.3750598409 5.756816975895349e-05 4.239817577670492 4.852036828921989 AAAAALSGS(ph)PPQTEKPTHYR ddPTM_PC-9_AZD4547_30min_R2 2 AAAAALSGSPPQTEKPTHYR 20 1 E9PDK2;A0A0A0MRZ1;Q9H9P5-5;Q9H9P5;Q9H9P5-6 E9PDK2 UNKL Putative E3 ubiquitin-protein ligase UNKL 1 AAAAALS(0.187)GS(0.812)PPQTEKPTHYR;AAAAALS(0.036)GS(0.962)PPQT(0.003)EKPTHYR 105.0 6.3147e-05 41617000.0 154225.0 161470.0 211557.0 273928.0 251620.0 237852.0 153360.0 241532.0 182540.0 208566.0 True False 203265.34192071867 213662.01978205086 208751.61595111166 210778.1317454117 216686.90627735303 222979.0768396477 167008.74290231385 204208.77925320624 192188.69173720386 201264.16782254918 1.0099430222469301 1.061599896760722 1.0372020922033376 1.0472710270575873 1.0766293306039543 1.107892573487021 0.8297986904929958 1.0146305796134227 0.9549076411189745 1.0 17.618730818548002 -7.233721796696227 24.99587113305061 0.951053388926601 1.056559825128613 0.5053296949715957 0.05181966083501335 596.7544875508081 538157.4209907264 0.019155695932360044 0.014834565673952856 5.8381897122877974e-08 7.233721796696227 0.10550643620201205 AAAAALSGS(ph)PPQTEKPTHYR ddPTM_PC-9_Lapatinib_30min_R1 1 AAAAALSGSPPQTEKPTHYR 20 1 E9PDK2;A0A0A0MRZ1;Q9H9P5-5;Q9H9P5;Q9H9P5-6 E9PDK2 UNKL Putative E3 ubiquitin-protein ligase UNKL 1 AAAAALS(0.178)GS(0.821)PPQT(0.001)EKPTHYR 56.817 0.008474899999999999 3481500.0 27970.0 24085.0 33526.0 24377.0 26731.0 27069.0 23432.0 26422.0 27208.0 22216.0 True False 27571.14267093019 24029.232662277976 30769.62169410248 26169.765899288155 25158.73513516803 25911.321970920966 24645.19430634345 27649.662578253257 24143.54852705831 26056.005999040754 1.0581492294692139 0.9222147347971369 1.1809032318781034 1.004365976130478 0.9655637604663678 0.9944471908655105 0.9458546450768684 1.0611627345830046 0.9266020482167201 1.0 14.66932833655684 -5.986096617373117 24.999253428577834 0.9841947706292138 1.0492737771102771 0.18402475100394156 0.06705376466998729 423.4069647101576 761309.0495310983 0.01820530370383912 0.026989332932130405 1.0325316731726874e-06 5.986096617373117 0.06507900648106335 AAAAAWEEPSS(ph)GNGTAR ddPTM_PC-9_AZD4547_30min_R2 1 AAAAAWEEPSSGNGTAR 17 0 Q9P258 Q9P258 RCC2 Protein RCC2 1 AAAAAWEEPS(0.231)S(0.766)GNGT(0.003)AR 149.6 9.013999999999999e-12 0.0 12164.0 9289.8 15339.0 18286.0 18363.0 15286.0 11938.0 17395.0 11967.0 12311.0 True False 16031.89897308234 12292.546178059694 15135.59483767545 14070.445215883734 15813.614418452555 14330.16400354361 13000.458873029604 14707.002447334191 12599.551188885289 11879.995637176766 1.3494869411326027 1.0347264892582881 1.2740404373812013 1.1843813453813288 1.3311128136247867 1.206243204223021 1.0943151218293807 1.2379636235985396 1.0605686713770144 1.0 13.536246685871243 -8.434097459604574 0.9154384689199245 0.9965706437655015 1.2198042020654016 0.3836314120222414 0.09273008661432589 0.6232134353269186 1.1558611278075364 0.08478502578488885 0.02967194983572028 3.680463714443478e-09 8.434097459604574 0.2232335582999001 AAAAGLGHPAS(ph)PGGSEDGPPGSEEEDAAR ddPTM_PC-9_Lapatinib_30min_R1 1 AAAAGLGHPASPGGSEDGPPGSEEEDAAR 29 0 Q99856 Q99856 ARID3A AT-rich interactive domain-containing protein 3A 1 AAAAGLGHPAS(0.968)PGGS(0.032)EDGPPGSEEEDAAR 84.31200000000001 3.5195e-08 3050300.0 10015.0 8178.0 9760.7 7681.2 6769.4 8371.2 8536.1 7762.2 8421.1 8194.2 True False 9872.184263473939 8159.0643434548265 8958.212923391584 8246.101071732051 6371.237201152464 8013.183290220305 8978.057490541927 8122.860149304273 7472.627039885722 9610.556551914826 1.0272229511522915 0.8489689748331171 0.9321221799175338 0.8580253419443312 0.6629415442004809 0.8337897235122916 0.9341870517117057 0.8452018470965512 0.7775436312683537 1.0 13.230404265238418 -1.769452255492167 1.0988464008722765 0.8414478811511633 192.07028753048175 0.24325225186730126 0.08849682674996191 2222.0714100123773 3.5204229635999504 0.027160130571118293 1070092.457628564 0.017003868767454158 1.769452255492167 191.22883964933058 AAAAPGAS(ph)PSPGGDAAWSEAGPGPR ddPTM_PC-9_AZD4547_30min_R2 1 AAAAPGASPSPGGDAAWSEAGPGPR 25 0 P52701-2;P52701;P52701-3;F8WAX8;F8W7G9 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 AAAAPGAS(0.97)PS(0.029)PGGDAAWS(0.001)EAGPGPR 127.07 1.1372e-07 5040200.0 15761.0 21513.0 23117.0 19972.0 17102.0 21467.0 25062.0 28244.0 26707.0 18324.0 True False 20772.670150834496 28466.65654035589 22810.453475620518 15367.763964324073 14727.68250200813 20124.665096432727 27292.46944847278 23879.538782552863 28118.677496578897 17682.48233739152 1.174759841660265 1.6098789749762716 1.2900028989360475 0.8690953945887606 0.8328967743892414 1.1381131174030328 1.5434750012875682 1.3504630360668872 1.5901996654122998 1.0 14.110033199779773 -7.24020331236783 23.61884664077309 1.4002396747224541 1.1520960978667831 0.14997389170481223 0.25110573889485316 755.0388267608539 839757.9936958973 0.10404713133909041 0.08048914413870847 5.7517061161390535e-08 7.24020331236783 -0.248143576855671 AAAAPGAS(ph)PSPGGDAAWSEAGPGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AAAAPGASPSPGGDAAWSEAGPGPR 25 0 P52701-2;P52701;P52701-3;F8WAX8;F8W7G9 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 AAAAPGAS(0.944)PS(0.056)PGGDAAWSEAGPGPR;AAAAPGAS(0.995)PS(0.005)PGGDAAWSEAGPGPR 218.22 2.6100999999999997e-38 16102600.0 56801.0 107877.0 80402.0 62398.0 79133.0 48894.0 70209.0 46032.0 45217.0 46509.0 True False 66416.28742911239 118586.3156257444 82319.08860628311 58902.042357045444 63627.45671099352 46329.912567032225 63558.29525085823 44823.70877493557 45878.21308284034 54940.71353495856 1.208871948611515 2.158441490758732 1.498325800845375 1.0721018815958099 1.1581112187505105 0.8432710386542884 1.1568523807106426 0.8158559634725971 0.8350494584248203 1.0 15.745588026888255 -5.7201673822372285 3.058101831454601 0.9738961421485992 1.7132933706237323 0.5986746510190041 0.24282782399530722 0.15189205481717555 2.891441046725451 0.06635596351329025 0.11964644137935768 1.904726472336314e-06 5.7201673822372285 0.7393972284751331 AAAAPGAS(ph)PSPGGDAAWSEAGPGPR ddPTM_PC-9_Lapatinib_30min_R1 2 AAAAPGASPSPGGDAAWSEAGPGPR 25 0 P52701-2;P52701;P52701-3;F8WAX8;F8W7G9 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 AAAAPGAS(0.934)PS(0.066)PGGDAAWSEAGPGPR;AAAAPGAS(0.963)PS(0.036)PGGDAAWS(0.001)EAGPGPR 242.9 2.5147999999999995e-70 10945400.0 22106.1 54592.0 52289.0 43424.0 60988.0 55573.0 59417.0 64923.0 52672.0 47500.0 True False 21790.862960237762 54465.595578122506 47990.00026137702 46617.54581821753 57400.80574702139 53196.272336990325 62493.321530386216 67939.55959306401 46739.524699250804 55710.311710228496 0.39114595289972015 0.9776573475556868 0.861420422685698 0.8367848677762555 1.0303443650716912 0.9548729975464023 1.1217550146809239 1.2195149785993786 0.8389743884823635 1.0 15.765656767731029 -4.76100257672153 7.283250851427096 0.9865774278056165 0.3801497888211877 0.6988540949895339 0.11641550324952986 0.06266091751456908 21.559619618476887 0.030925991483106832 0.18696225647080297 1.7337937109164688e-05 4.76100257672153 -0.6064276389844288 AAAAPGASPS(ph)PGGDAAWSEAGPGPR ddPTM_PC-9_AZD4547_30min_R2 1 AAAAPGASPSPGGDAAWSEAGPGPR 25 0 P52701-2;P52701;P52701-3;F8WAX8;F8W7G9 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 AAAAPGAS(0.218)PS(0.782)PGGDAAWSEAGPGPR 189.15 4.8158e-21 8665700.0 12605.0 17958.0 20332.0 17242.0 16844.0 19392.0 17390.0 26083.0 19835.0 16518.0 True False 16613.12779971249 23762.572312169905 20062.384395307192 13267.123286244529 14505.501348603968 18179.41517445491 18937.67631110613 22052.471677712994 20883.437606044932 15939.709847687895 1.0422478174608854 1.4907782223913406 1.2586417561557623 0.8323315426076571 0.9100229230777395 1.1405110474512112 1.1880816208115044 1.3834926663305465 1.3101516781420046 1.0 13.960337747578482 -10.11845235624127 15.327323836784867 0.9999999758380369 1.1727246353562268 0.06695118757800844 0.1936560327805691 0.0 0.0 0.20644078251255968 0.05006924421967335 7.612856503601734e-11 10.11845235624127 0.17272465951818994 AAAAPGASPS(ph)PGGDAAWSEAGPGPR ddPTM_PC-9_Lapatinib_30min_R1 1 AAAAPGASPSPGGDAAWSEAGPGPR 25 0 P52701-2;P52701;P52701-3;F8WAX8;F8W7G9 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 AAAAPGAS(0.039)PS(0.959)PGGDAAWS(0.002)EAGPGPR 202.21 2.1458999999999997e-71 0.0 6971.1 15336.0 13328.0 9149.4 15903.0 14489.0 15645.0 15319.0 14012.0 12018.0 True False 6871.690835656831 15300.49043424104 12232.223287567806 9822.277397503667 14967.616806500977 13869.339245508649 16455.021548427074 16030.776664758969 12433.821007098686 14095.295287021589 0.48751662847276583 1.0855033628368997 0.867823130944321 0.6968479338313435 1.0618874242586878 0.9839693999372264 1.167412332509148 1.1373140000493283 0.8821256138243003 1.0 13.782926081271857 -6.2780641502091585 24.13065365239189 1.0493411281734304 0.811885693555961 0.37472802159154117 0.15904436596859203 589.7045146412701 855946.7054339914 0.048346669065860694 0.05498917058561111 5.271519893579497e-07 6.2780641502091585 -0.23745543461746943 AAAAPGASPS(ph)PGGDAAWSEAGPGPRPLAR ddPTM_PC-9_AZD4547_30min_R2 4 AAAAPGASPSPGGDAAWSEAGPGPRPLAR 29 1 P52701-2;P52701;P52701-3;F8WAX8;F8W7G9 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 AAAAPGAS(0.081)PS(0.915)PGGDAAWS(0.005)EAGPGPRPLAR;AAAAPGAS(0.055)PS(0.945)PGGDAAWSEAGPGPRPLAR;AAAAPGAS(0.269)PS(0.723)PGGDAAWS(0.008)EAGPGPRPLAR;AAAAPGAS(0.191)PS(0.809)PGGDAAWSEAGPGPRPLAR 114.84 1.7115e-13 310494000.0 137671.0 130076.0 189314.0 277896.0 226231.0 197681.0 178794.0 243241.0 152510.0 223602.0 True False 181447.51426530894 172120.52322518165 186803.57266442993 213831.3706504007 194822.7306813123 185319.97581999877 194706.3196301272 205653.69257211982 160571.36724466432 215773.76203915238 0.8409155615147735 0.7976897728369319 0.8657381272822885 0.9909980186172995 0.9029027850288929 0.8588624217729135 0.9023632799005354 0.9530987022175742 0.7441653967896638 1.0 17.719159919070997 AAAAPGASPS(ph)PGGDAAWSEAGPGPRPLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AAAAPGASPSPGGDAAWSEAGPGPRPLAR 29 1 P52701-2;P52701;P52701-3;F8WAX8;F8W7G9 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 AAAAPGAS(0.161)PS(0.839)PGGDAAWSEAGPGPRPLAR;AAAAPGAS(0.075)PS(0.879)PGGDAAWS(0.047)EAGPGPRPLAR;AAAAPGAS(0.128)PS(0.871)PGGDAAWS(0.001)EAGPGPRPLAR;AAAAPGAS(0.108)PS(0.892)PGGDAAWS(0.001)EAGPGPRPLAR 98.76 4.698300000000001e-11 232787000.0 208785.0 178914.0 244818.0 254200.0 313381.0 220443.0 230121.0 260878.0 205432.0 192040.0 True False 244128.17680828169 196675.3995185659 250655.38959743554 239957.9981275195 251976.2426743315 208882.58101227717 208322.27294823687 254030.2289230897 208436.05436083855 226855.33181219635 1.0761403527882905 0.8669639719175077 1.1049129310522101 1.0577578063105446 1.1107353777469584 0.9207743954865559 0.9183045039501113 1.1197895455831306 0.9188060632993792 1.0 17.791413042384754 -6.7701618208344625 24.999381146994303 0.9794448674948868 1.0377314501328063 0.1353604513611939 0.08476871363832064 486.30589714468084 1393792.8773030497 0.03002733894673769 0.026888775046025857 1.6976109941513481e-07 6.7701618208344625 0.058286582637919526 AAAAPGASPS(ph)PGGDAAWSEAGPGPRPLAR ddPTM_PC-9_Lapatinib_30min_R1 4 AAAAPGASPSPGGDAAWSEAGPGPRPLAR 29 1 P52701-2;P52701;P52701-3;F8WAX8;F8W7G9 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 AAAAPGAS(0.041)PS(0.959)PGGDAAWSEAGPGPRPLAR;AAAAPGAS(0.197)PS(0.803)PGGDAAWSEAGPGPRPLAR;AAAAPGAS(0.406)PS(0.594)PGGDAAWSEAGPGPRPLAR;AAAAPGAS(0.019)PS(0.981)PGGDAAWSEAGPGPRPLAR 95.12200000000001 6.9282e-11 285381000.0 316393.0 238462.0 329594.0 232797.0 253284.0 249592.0 225962.0 175592.0 230006.0 201142.0 True False 311881.1778006295 237909.85589006182 302496.0535896328 249917.66796802607 238386.33309550327 238917.53198736938 237661.2067194428 183750.64535011147 204100.3022094448 235909.12669513226 1.322039474139026 1.008480931717047 1.2822566800501596 1.0593810908002605 1.0105006806437478 1.012752390441108 1.0074269276854844 0.7789043515369131 0.8651649262947155 1.0 17.84787170811849 -6.479527159598416 0.7403613599125185 0.88183547951348 1.2073229302791784 0.5716693234070052 0.10188176257734606 0.5079852240007585 0.6188214673923802 0.06375255090343367 0.0866036785307203 3.3149183856354935e-07 6.479527159598416 0.3254874507656984 AAAGEEETAAAGS(ph)PGR ddPTM_PC-9_AZD4547_30min_R2 2 AAAGEEETAAAGSPGR 16 0 Q9NS37;E9PIM0 Q9NS37 CREBZF CREB/ATF bZIP transcription factor 1 AAAGEEETAAAGS(1)PGR;AAAGEEET(0.001)AAAGS(0.999)PGR 119.54 0.00010701 8155000.0 3623.4 3923.6 5631.5 13490.2 8271.9 5886.6 4307.6 7310.0 5563.6 5256.0 True False 4775.565828598037 5191.826969820126 5556.822630443264 10380.242811512344 7123.489468387387 5518.509971428746 4690.96805507307 6180.407467088992 5857.680537685485 5071.989039801891 0.9415568115629384 1.0236274031899162 1.0955904255385203 2.046582263891838 1.404476510593096 1.0880366515232645 0.9248774037682654 1.2185372284105715 1.1549079644529918 1.0 12.308335912584095 -6.777789251665795 22.568300136935182 1.0814054602179577 1.316738849392474 0.12594358083743162 0.2951832397914327 185.65682355072056 256264.16469869466 0.11483644932924406 0.10169401286164798 1.6680564672274135e-07 6.777789251665795 0.2353333891745164 AAAGEEETAAAGS(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAAGEEETAAAGSPGR 16 0 Q9NS37;E9PIM0 Q9NS37 CREBZF CREB/ATF bZIP transcription factor 1 AAAGEEET(0.001)AAAGS(0.999)PGR 122.12 6.3655e-05 4405100.0 7762.9 5322.9 5620.8 7818.1 9392.5 6157.3 4918.3 6330.1 7020.2 2469.0 True False 9077.005645736106 5851.322334179419 5754.821189002702 7380.077203622188 7552.107049625402 5834.400348692842 4452.403018591576 6163.94158229535 7122.85714408642 2916.6101554067545 3.112176520715095 2.006206528264449 1.9731197802814093 2.5303612105790503 2.5893440148747526 2.0004045922548634 1.526567755494439 2.1133923472318563 2.442169767146359 1.0 11.51007684798158 -6.9132578809745375 5.726916171755238 1.850026500595371 2.394098871634789 0.3137716336295203 0.4635604753481066 0.31284970477387947 16.21459935570864 0.16454621054229818 0.14470360574175922 1.2210743795709661e-07 6.9132578809745375 0.5440723710394177 AAAGEEETAAAGS(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 1 AAAGEEETAAAGSPGR 16 0 Q9NS37;E9PIM0 Q9NS37 CREBZF CREB/ATF bZIP transcription factor 1 AAAGEEETAAAGS(1)PGR 148.18 3.0299999999999998e-05 3595900.0 5702.6 7082.2 7408.4 5243.7 7215.0 6469.8 6849.0 2271.5 6452.3 6522.1 True False 5621.27987827124 7065.801601029071 6799.309949250998 5629.339190470413 6790.627885235768 6193.101735840426 7203.607707585623 2377.042182518442 5725.57402826883 7649.436294848027 0.7348619769612604 0.9237022610133979 0.8888641838654703 0.7359155594591762 0.887729189902441 0.8096154405536449 0.9417174586364392 0.31074736632807887 0.7484962038477349 1.0 12.90113772075602 AAAGEEETAAAGS(ph)PGRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAAGEEETAAAGSPGRK 17 1 Q9NS37;E9PIM0 Q9NS37 CREBZF CREB/ATF bZIP transcription factor 1 AAAGEEETAAAGS(1)PGRK 64.5 0.010431000000000001 8303600.0 18227.0 12141.0 12227.0 12622.0 20607.0 15671.0 14668.0 14783.0 16909.0 13187.0 True False 21312.47110034032 13346.278242926295 12518.538051155723 11914.830261076124 16569.206278587255 14849.185172781165 13278.54085287626 14394.961913883219 17156.26213631482 15577.698711765435 1.3681398963149518 0.8567554482772346 0.8036192176255658 0.7648645978803762 1.0636491682865172 0.9532335582768691 0.8524070916102209 0.9240749985112419 1.1013348283181994 1.0 13.927194499833046 -10.19510604682996 7.781314899259866 1.0000010525875545 0.949495006376658 0.0 0.1689393453185938 0.0 0.0 0.16216040717604704 0.03932967571058884 6.381076528584255e-11 10.19510604682996 -0.050506046210896494 AAAGPLDMSLPS(ph)TPDIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAAGPLDMSLPSTPDIK 17 0 K7ELQ4;P17544-2;P17544;P17544-4 K7ELQ4 ATF7 Cyclic AMP-dependent transcription factor ATF-7 1 AAAGPLDMS(0.026)LPS(0.487)T(0.487)PDIK 124.62 3.536e-05 5444200.0 35263.0 35956.0 35143.0 49549.0 62074.0 73181.0 82566.0 67871.0 78529.0 57763.0 True False 41232.32942400289 39525.474055074345 35980.9424005697 46772.930170025415 49911.045301937476 69343.2595322123 74744.75075392578 66089.45816526872 79677.33806272777 68234.9746483436 0.6042697258480451 0.5792553490167351 0.5273093832891624 0.685468565220033 0.7314583988513149 1.016242182100607 1.0954023378645779 0.9685569388113349 1.1676905937659336 1.0 16.058223778889097 -6.611401746518928 1.7349111842901361 1.0637747904740833 0.5824230148606575 0.9249027349970627 0.061444217083201386 0.08450580162070234 0.521492041503351 0.023497157767892157 0.02401526088817187 2.446798769853905e-07 6.611401746518928 -0.4813517756134258 AAAGPLDMSLPST(ph)PDIK ddPTM_PC-9_AZD4547_30min_R2 2 AAAGPLDMSLPSTPDIK 17 0 K7ELQ4;P17544-2;P17544;P17544-4 K7ELQ4 ATF7 Cyclic AMP-dependent transcription factor ATF-7 1 AAAGPLDMS(0.002)LPS(0.176)T(0.823)PDIK;AAAGPLDMS(0.003)LPS(0.314)T(0.684)PDIK 119.96 0.00035094 18368700.0 65191.0 58535.0 77318.0 108133.0 110864.0 97122.0 78623.0 99134.0 78173.0 97271.0 True False 85920.38194296382 77455.29403568682 76292.71280131621 83204.60748819615 95472.4472519373 91048.94598666497 85620.29468706725 83815.11817269497 82305.06518665749 93865.57189698798 0.9153556539053154 0.8251725576304965 0.8127869596857412 0.8864230601983482 1.0171189001726082 0.9699929819485456 0.9121586643186977 0.8929271561321461 0.8768397562951251 1.0 16.518308481398286 -6.006319777601814 24.42743675717393 0.9402605998785195 0.8486939893962351 0.43293992231560396 0.0486813474827846 218.76303419151483 845581.2850161584 0.014738839127820744 0.02102322423125935 9.855535404096725e-07 6.006319777601814 -0.09156661048228443 AAAGPLDMSLPST(ph)PDIK ddPTM_PC-9_Lapatinib_30min_R1 1 AAAGPLDMSLPSTPDIK 17 0 K7ELQ4;P17544-2;P17544;P17544-4 K7ELQ4 ATF7 Cyclic AMP-dependent transcription factor ATF-7 1 AAAGPLDMS(0.405)LPS(0.034)T(0.562)PDIK 141.06 0.0003638 7477500.0 10243.0 11535.0 11703.0 9772.4 15622.0 17302.0 16753.0 15484.0 17234.0 15846.0 True False 10096.932941663854 11508.291416208283 10740.824514886408 10491.094895770746 14703.14467403371 16562.03379293194 17620.388366941435 16203.443167121095 15292.92543793454 18584.959986532223 0.5432851590200193 0.6192260529238632 0.5779310002641842 0.5644938113061972 0.7911313602336777 0.8911525128347751 0.9480993437548547 0.871857845207258 0.8228656639033235 1.0 14.181847961626243 -6.428710298705779 2.685725645836101 0.9009284188012436 0.5773840023549274 0.9129314387262508 0.04809612217433541 0.07787242858785799 1.0971461471963757 0.016381621800535713 0.018549459377660244 3.726401974370792e-07 6.428710298705779 -0.32354441644631626 AAAGVGGS(ph)LR ddPTM_PC-9_AZD4547_30min_R2 2 AAAGVGGSLR 10 0 Q9BRK4 Q9BRK4 LZTS2 Leucine zipper putative tumor suppressor 2 1 AAAGVGGS(1)LR;AAAGVGGS(1)LR 89.679 0.0091954 22091700.0 70564.0 77758.0 92000.0 134761.0 102572.0 85648.0 75717.0 105393.0 88437.0 92026.0 True False 93001.88417762083 102891.75285943343 90780.01988826794 103693.93348669517 88331.64832159871 80292.41702050917 82455.6663167351 89106.93354020672 93111.59927228624 88804.1977505343 1.047269009049308 1.1586361395716158 1.0222491975355046 1.1676692781797162 0.9946787489678917 0.9041511443644125 0.9285109083285312 1.0034090256692918 1.048504480991452 1.0 16.438340253543096 -6.414371616721736 6.585213528163082 0.9715303186589619 1.0971839639456722 0.5234693368161172 0.05571092701225984 0.19395963662422303 10.25801167792894 0.01742513568623034 0.019733046185918438 3.8514865296328214e-07 6.414371616721736 0.1256536452867103 AAAGVGGS(ph)LR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAAGVGGSLR 10 0 Q9BRK4 Q9BRK4 LZTS2 Leucine zipper putative tumor suppressor 2 1 AAAGVGGS(1)LR 82.26100000000001 0.015156999999999999 8715100.0 74445.0 63799.0 77381.0 77894.0 106620.0 85759.0 70269.0 60444.0 67721.0 54918.0 True False 87047.0681442274 70132.54308709777 79226.05650907659 73529.85171575529 85728.57637807414 81261.64706990866 63612.611616495815 58857.40904571178 68711.291509455 64874.19866935118 1.3417825565427979 1.0810544796791581 1.2212259747958278 1.1334221188691667 1.3214587330012801 1.2526034808395943 0.9805533312359606 0.9072545056886855 1.0591466703066437 1.0 15.985357192859766 -7.266679975942566 24.67498650445349 0.9790098150985863 1.2187183359479834 0.6763666758955554 0.08068170737985873 218.19237559866573 1027338.319030092 0.03255933299226238 0.02269933105751691 5.411529422598238e-08 7.266679975942566 0.2397085208493971 AAAGVGGS(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 1 AAAGVGGSLR 10 0 Q9BRK4 Q9BRK4 LZTS2 Leucine zipper putative tumor suppressor 2 1 AAAGVGGS(1)LR 66.92 0.044945 7827100.0 61515.0 46601.0 55295.0 43582.0 41377.0 41582.0 38676.0 47953.0 48254.0 44414.0 True False 60637.78481953061 46493.09824765692 50748.85854487256 46787.16566529008 38943.28621031191 39803.63479237635 40678.4540368786 50181.07144103319 42819.12638285327 52090.90072206498 1.1640763353866386 0.8925378060887147 0.9742365334714984 0.8981830802835722 0.747602473186187 0.7641187662457924 0.7809128556620978 0.9633366047705371 0.822007793862464 1.0 15.668743763000544 -1.5228914331320225 0.8726274128340188 0.8465034137186263 127.3757888019542 0.509397025399158 0.08614618699477088 627.6875261117598 1.5741114226243493 0.029913647989457434 157903.73545432385 0.02999912356705794 1.5228914331320225 126.52928538823558 AAALEFLNR ddPTM_PC-9_Lapatinib_30min_R1 2 AAALEFLNR 9 0 P31948-2;P31948;F5H783;F5GXD8 P31948-2 STIP1 Stress-induced-phosphoprotein 1 0 ; 137.9 0.004231899999999999 7248000.0 39294.0 35698.0 40594.0 36159.0 33662.0 36031.0 38281.0 46184.0 34706.0 34530.0 False True 38733.66035436294 35615.34347427858 37256.5180173715 38818.25348288796 31682.06734203833 34490.038122363345 40263.00286962847 48329.87724298115 30797.044809617986 40498.46449166715 0.9564229370309253 0.8794245392095469 0.9199489038661526 0.9585117354480215 0.7823029277704378 0.8516381683917896 0.9941859123550936 1.1933755476809589 0.7604496910235867 1.0 15.305579588478743 -7.308044562673773 8.745399992682774 1.0034066225860367 0.8902570488545937 0.1498716740874675 0.10880563945438146 0.6809857582506392 121.62806625900903 0.04417218071877039 0.029825711281353893 4.9198905041551455e-08 7.308044562673773 -0.11314957373144308 AAALS(ph)LSTLASPK ddPTM_PC-9_AZD4547_30min_R2 1 AAALSLSTLASPK 13 0 P98172 P98172 EFNB1 Ephrin-B1 1 AAALS(0.985)LS(0.005)T(0.01)LASPK 140.82 7.4487e-05 4952200.0 21277.0 39616.0 43115.0 48321.0 48506.0 31155.0 44707.0 53006.0 30835.0 32441.0 True False 28042.64341090702 52421.09726689621 42543.26692915944 37181.34000200796 41771.779174506315 29206.872924924843 48685.836391065066 44815.14065670574 32464.87514909985 31305.25046427189 0.8957808353238247 1.6745145459456858 1.358981841647084 1.1877030035087035 1.3343378045219503 0.9329704280199934 1.555197152842758 1.431553493170497 1.0370424982272997 1.0 14.934117023401079 -8.341645017702437 6.949570868208607 1.0100827652815454 1.304965976545586 0.1858621289965955 0.23218570969642982 0.460521561288631 33.53723707297228 0.21590221098713136 0.05605953847083167 4.553601089327496e-09 8.341645017702437 0.2948832112640407 AAALS(ph)LSTLASPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAALSLSTLASPK 13 0 P98172 P98172 EFNB1 Ephrin-B1 1 AAALS(1)LSTLASPK 159.52 0.0002689 3857800.0 28822.0 22189.0 22177.0 20364.0 48352.0 28013.0 22842.0 22552.0 23972.0 21310.0 True False 33700.99533955169 24391.777278007707 22705.783786740845 19223.07110097877 38877.77269773622 26543.948965931893 20678.24039824102 21960.033895819135 24322.545149431586 25173.334310132803 1.3387577078331783 0.9689529792717804 0.9019776048340677 0.7636283244862432 1.544402986857688 1.0544470843199898 0.821434305979784 0.8723530075624409 0.9662027624064582 1.0 14.619608699508863 -7.139767910014408 6.8000377796218565 0.9054452149354338 1.0880458824778687 0.1491016347155394 0.2112515549272161 0.53574997730408 27.59113287188965 0.08450903559627511 0.06536974833902233 7.248232071449509e-08 7.139767910014408 0.18260066754243487 AAALS(ph)LSTLASPK ddPTM_PC-9_Lapatinib_30min_R1 2 AAALSLSTLASPK 13 0 P98172 P98172 EFNB1 Ephrin-B1 1 AAALS(0.975)LS(0.008)T(0.018)LASPK;AAALS(0.993)LS(0.003)T(0.003)LASPK 160.84 0.00029559 2960600.0 78081.0 68625.0 32556.0 24880.0 36617.0 26768.0 27331.0 20289.6 48923.0 15966.9 True False 76967.55062169836 68466.10302880753 29879.371349794215 26709.758197246956 34463.26005179184 25623.195039255705 28746.065448389934 21232.328886826403 43412.77655797095 18726.757390443086 4.110030851415717 3.656057565190018 1.5955443180484996 1.4262884727111311 1.8403218097640137 1.3682665132583023 1.535026318174018 1.1337963345251643 2.318221764336307 1.0 14.192813492599758 -5.225782634780733 3.802335203799337 1.5222634763884524 4.007037255875552 0.8805718978404589 0.3486769745858828 0.06297066673023141 1.9726217408907674 0.08559157014757607 0.24386874421893664 5.945896774263657e-06 5.225782634780733 2.4847737794871 AAAPPQPS(ph)PPPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AAAPPQPSPPPTK 13 0 J3KR72;P49848-4;P49848-2;P49848;P49848-3 J3KR72 TAF6 Transcription initiation factor TFIID subunit 6 1 AAAPPQPS(0.997)PPPT(0.003)K;AAAPPQPS(0.993)PPPT(0.007)K 90.759 0.023148 0.0 32750.0 31674.0 32959.0 38550.0 42755.0 49327.0 53801.0 50777.0 46810.0 35859.0 True False 38293.92815801535 34818.385393826466 33744.86755770356 36390.16848078628 34377.46466933557 46740.20528477932 48704.57979449106 49444.157552678626 47494.50769418044 42359.95284031219 0.9040125304760166 0.8219646873801821 0.7966219340449782 0.8590700895718487 0.8115557823902952 1.1034055080509586 1.149778895602097 1.167238257773146 1.1212124780503039 1.0 15.370413362716205 -6.779031529216317 8.188398412426995 1.1220115359023428 0.8363783941902336 0.8763674064614481 0.050515465054388725 0.05245503041743182 18.191864619937757 0.016985748460120933 0.01540197168702354 1.663291893151854e-07 6.779031529216317 -0.2856331417121092 AAAPPQPS(ph)PPPTK ddPTM_PC-9_Lapatinib_30min_R1 2 AAAPPQPSPPPTK 13 0 J3KR72;P49848-4;P49848-2;P49848;P49848-3 J3KR72 TAF6 Transcription initiation factor TFIID subunit 6 1 AAAPPQPS(0.999)PPPT(0.001)K;AAAPPQPS(0.845)PPPT(0.155)K 94.71700000000001 0.0036976 29869000.0 73159.0 59452.0 70510.0 69053.0 82804.0 107690.0 98500.0 91301.0 103028.0 69269.0 True False 72115.7392442827 59314.342546720014 64712.93997647097 74131.38797405506 77933.63151892759 103084.34973765115 103599.84803579844 95543.17777068743 91423.90170706266 81242.05435485928 0.8876651362025693 0.7300940752635249 0.7965448497130517 0.9124755468424597 0.9592769673021715 1.2688545428379536 1.2751997577914753 1.1760310411817245 1.1253273004118016 1.0 16.309939100843962 -6.456436198098525 2.2029431510825193 1.1852793456639006 0.813162279024393 0.7574401609356919 0.08935437824028483 0.1417335163447621 1.36456987053424 0.03170923801776853 0.03568812687916204 3.4959386441869414e-07 6.456436198098525 -0.3721170666395076 AAASPPT(ph)PIR ddPTM_PC-9_AZD4547_30min_R2 2 AAASPPTPIR 10 0 Q6PGN9-4;Q5T2Z1;Q6PGN9-2 Q6PGN9-4 PSRC1 1 AAAS(0.381)PPT(0.619)PIR;AAAS(0.088)PPT(0.912)PIR 111.27 0.003961699999999999 22874000.0 98429.0 86058.0 149207.0 206912.0 152161.0 160397.0 125628.0 165030.0 102070.0 143253.0 True False 129727.37454961514 113874.5655440872 147228.4176898779 159211.63515853303 131036.0716400459 150367.35023396442 136808.64862631657 139528.40551213315 107465.21181996516 138237.7560728196 0.938436634353921 0.8237587818200797 1.065037670405488 1.1517232316377082 0.9479036361890881 1.0877444375960161 0.989661960038253 1.0093364466841726 0.7773940699916716 1.0 17.0767921788731 -10.18413328718637 8.40350222378918 0.9999999998350144 0.9837692313330284 0.00038502138428908594 0.10855772294653233 0.0 0.0 0.1077122103226835 0.026124048254657004 6.544352937215652e-11 10.18413328718637 -0.016230768501986015 AAASPPT(ph)PIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAASPPTPIR 10 0 Q6PGN9-4;Q5T2Z1;Q6PGN9-2 Q6PGN9-4 PSRC1 1 AAAS(0.275)PPT(0.725)PIR 89.029 0.023499000000000003 7390700.0 32462.0 25841.0 32333.0 45784.0 51170.0 41195.0 36898.0 41180.0 40611.0 25907.0 True False 37957.17544627464 28406.32370278052 33103.941343585335 43218.87091373074 41143.605826918516 39034.66168034713 33402.7543216136 40099.068633816605 41204.85904653625 30603.734020300824 1.2402792228260757 0.9281979670826225 1.0816961525553062 1.4122090750449514 1.3443982293018926 1.275486894979995 1.091460091093984 1.3102671918144728 1.346399724269046 1.0 14.901420069196622 -5.642476412752377 9.102243720758748 1.2649011210907077 1.0647930325393788 0.24265976165345182 0.1365927495394674 0.32617887657930067 24.42329357042302 0.03624770366882521 0.06285469517109812 2.2778419518407546e-06 5.642476412752377 -0.2001080885513289 AAASPPT(ph)PIR ddPTM_PC-9_Lapatinib_30min_R1 2 AAASPPTPIR 10 0 Q6PGN9-4;Q5T2Z1;Q6PGN9-2 Q6PGN9-4 PSRC1 1 AAAS(0.052)PPT(0.948)PIR;AAAS(0.041)PPT(0.959)PIR 105.17 0.0061121000000000005 24963000.0 165921.0 155447.0 169105.0 138298.0 178377.0 143190.0 140978.0 136954.0 160750.0 109223.0 True False 163554.9361138149 155087.07202213554 155201.83966417698 148468.89626860403 167885.21556267532 137066.09749219305 148277.15102934837 143317.38281515744 142644.64222745603 128102.05001950053 1.2767550253014492 1.2106525383358595 1.2115484462625785 1.1589892296493547 1.3105583832352312 1.0699758315446783 1.157492413328098 1.1187750921498971 1.1135234932285762 1.0 16.96693403777681 -7.796673178245809 0.117350882472052 0.8476321608136453 1.4171816137330127 0.6357771314998174 0.053645713984310985 4.742745498278649 0.5541851041938156 1.165349357523025 1.261881224566402 1.5970805539835937e-08 7.796673178245809 0.5695494529193673 AAAT(ph)GNASPGKLEHSK ddPTM_PC-9_AZD4547_30min_R2 1 AAATGNASPGKLEHSK 16 1 H0Y6H0;Q8NB78 H0Y6H0 KDM1B Lysine-specific histone demethylase 1B 1 AAAT(0.621)GNAS(0.379)PGKLEHSK 85.837 0.0033384 9937000.0 24365.0 17458.0 23274.0 36440.0 31033.0 27090.0 27197.0 23901.0 22144.0 25421.0 True False 32112.56317651686 23100.957090202817 22965.371553038556 28039.32099238779 26724.60361857202 25396.05801753215 29617.480312429736 20207.64964034117 23314.486632128024 24531.018527550197 1.309059513385146 0.9417039518460552 0.9361768459490053 1.1430149531254685 1.089420872947377 1.0352630890156658 1.207348169386732 0.8237590957605957 0.9504084229500738 1.0 14.582319515366693 -7.768586801844383 24.999996999901672 0.9153128362031853 1.0819823831014412 0.3113280057342742 0.11444067371777063 210.87467056046097 737575.3565841533 0.060031480514796204 0.029794068980867963 1.703778753352213e-08 7.768586801844383 0.16666954689825597 AAAT(ph)PESQEPQAK ddPTM_PC-9_AZD4547_30min_R2 4 AAATPESQEPQAK 13 0 P49006 P49006 MARCKSL1 MARCKS-related protein 1 AAAT(1)PESQEPQAK;AAAT(0.999)PES(0.001)QEPQAK;AAAT(0.995)PES(0.005)QEPQAK;AAAT(0.971)PES(0.029)QEPQAK 155.09 0.00014852 87380000.0 235869.0 219696.0 286790.0 390113.0 358266.0 320986.0 277890.0 342941.0 277494.0 315738.0 True False 310870.43562002224 290708.435610562 282986.9772147432 300178.4750357677 308526.95002131036 300914.6946775778 302621.671655738 289947.3484502007 292161.7663247707 304684.10872316814 1.0203040681142805 0.9541306136011699 0.9287881091030623 0.9852121145855552 1.012612542591231 0.9876284520994983 0.9932309004362809 0.9516326587076549 0.9589005726262702 1.0 18.216954730404282 -4.7451140546105846 24.887437658632837 0.9742347722679474 1.0203042074389645 0.23735962717992432 0.024521452340338992 1519.0625380800084 2315630.97505771 0.006650687911115905 0.17455293648408035 1.7983985568747284e-05 4.7451140546105846 0.04606943517101714 AAAT(ph)PESQEPQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AAATPESQEPQAK 13 0 P49006 P49006 MARCKSL1 MARCKS-related protein 1 AAAT(0.65)PES(0.35)QEPQAK;AAAT(1)PESQEPQAK;AAAT(0.997)PES(0.003)QEPQAK;AAAT(0.994)PES(0.006)QEPQAK 158.89 0.00042094 65689000.0 192258.0 189366.0 196976.0 234319.0 269588.0 223162.0 230497.0 214404.0 210805.0 183506.0 True False 224803.48213141088 208165.00500370478 201672.6548756397 221190.86610244724 216764.1666536504 211458.99186575122 208662.65550623252 208776.12217981572 213887.624321122 216774.18516730348 1.0370399130224408 0.9602850304479094 0.930335199830143 1.0203745705778344 0.9999537836405873 0.9754805061430628 0.9625807397001143 0.9631041722919408 0.9866840193911759 1.0 17.725833436162794 -4.751869301516263 24.931593415199877 0.9765069699756221 1.0370400374576758 0.3490614563306943 0.02428832581899742 450.1592646667232 1172652.6213659889 0.006316075648389928 0.07978953039356196 1.7706417428262298e-05 4.751869301516263 0.06053306748205367 AAAT(ph)PESQEPQAK ddPTM_PC-9_Lapatinib_30min_R1 4 AAATPESQEPQAK 13 0 P49006 P49006 MARCKSL1 MARCKS-related protein 1 AAAT(0.927)PES(0.073)QEPQAK;AAAT(1)PESQEPQAK;AAAT(0.996)PES(0.004)QEPQAK;AAAT(0.799)PES(0.201)QEPQAK 186.29 0.00010021 91554000.0 250576.0 205034.0 217752.0 196453.0 235113.0 222149.0 202079.0 197655.0 242915.0 195298.0 True False 247002.7402899892 204559.25637025147 199849.2711070274 210900.80896799633 221284.11558994313 212648.20512461182 212541.66183985918 206838.77287505296 215555.35469164862 229054.99908177293 1.0783555970407304 0.89305737569702 0.872494693013362 0.9207430958217353 0.9660741589444395 0.9283718145295582 0.9279066717246435 0.9030092061043001 0.9410637425760574 1.0 17.8053345241811 -8.563818131452566 19.813153103159177 1.0000000017917423 0.9319612079309073 0.10806397483791086 0.05351464529336638 2576.8788267382147 1247115.1648179996 0.050670095654089184 0.013082962407720293 2.7301208301663475e-09 8.563818131452566 -0.068038793860835 AAATGNAS(ph)PGKLEHSK ddPTM_PC-9_AZD4547_30min_R2 1 AAATGNASPGKLEHSK 16 1 H0Y6H0;Q8NB78 H0Y6H0 KDM1B Lysine-specific histone demethylase 1B 1 AAAT(0.009)GNAS(0.991)PGKLEHSK 49.036 0.043336 21778000.0 74647.0 76696.0 88066.0 109050.0 116300.0 94883.0 86601.0 87278.0 87597.0 110710.0 True False 98383.19324594516 101486.48212797543 86898.1872986978 83910.20730570488 100153.75248412728 88949.95101061265 94308.32123163335 73791.19054891824 92227.19858718025 106834.07659750115 0.9208971180291584 0.9499448617909353 0.8133939101293299 0.7854254932331913 0.9374701001203757 0.8325990530693013 0.8827550556452249 0.6907083666471661 0.8632751040161791 1.0 16.705012367687274 -5.2565931105568025 24.82052071097861 0.8409228323305565 0.9354209984788618 0.14388972592460036 0.07985601700354271 596.5267431069399 3055126.934610728 0.019824945670090906 0.04894133962486375 5.538687845213056e-06 5.2565931105568025 0.09449816614830531 AAAYDIS(ph)EDEED ddPTM_PC-9_AZD4547_30min_R2 2 AAAYDISEDEED 12 0 P49585 P49585 PCYT1A Choline-phosphate cytidylyltransferase A 1 AAAYDIS(1)EDEED;AAAYDIS(1)EDEED 107.11 0.0015904000000000003 56860000.0 98339.0 95349.0 122294.0 176089.0 146487.0 131461.0 106746.0 146635.0 114581.0 109646.0 True False 129608.75642173178 126168.69959867961 120672.30165451982 135494.40159793026 126149.80859967622 123240.72288825367 116246.18720559697 123975.93008708535 120637.51773825224 105807.32691364478 1.2249506740446499 1.192438210840095 1.140490977085237 1.280576738400307 1.1922596693387224 1.164765489150267 1.0986591439028786 1.171714036290407 1.140162229376716 1.0 16.69108000865605 -10.879028516661473 0.19587296367286988 0.8276862461138128 1.2326752252313997 0.6808321356421223 0.040402145121685315 14.815971107010109 0.548840485255767 1.400938648185734 0.13083127317459975 1.3212088780686313e-11 10.879028516661473 0.4049889791175869 AAAYDIS(ph)EDEED ddPTM_PC-9_Lapatinib_30min_R1 2 AAAYDISEDEED 12 0 P49585 P49585 PCYT1A Choline-phosphate cytidylyltransferase A 1 AAAYDIS(1)EDEED;AAAYDIS(1)EDEED 117.52 0.000627 58816000.0 100309.0 117118.0 145819.0 110241.0 126615.0 130749.0 112617.0 105655.0 141169.0 101276.0 True False 98878.57526558219 116846.82046670868 133830.3246976178 118348.49089319546 119167.75463466774 125157.17006080544 118447.75722078691 110564.11701254064 125269.06064452707 118781.42165821271 0.8324414195858009 0.9837129311596325 1.1266940808530437 0.9963552316601918 1.0032524697133756 1.0536763099278152 0.9971909374987453 0.9308199503680219 1.0546182971692508 1.0 16.857949679451373 -4.791496484614779 4.1974006382191025 1.018835231811637 0.8196482129201036 0.5707697828304088 0.048600686474177604 0.14935839603381973 5.137197610901656 0.012351427871222512 0.08637908742381702 1.6162313085953337e-05 4.791496484614779 -0.19918701889153334 AACPCPQS(ph)SPPEQK ddPTM_PC-9_AZD4547_30min_R2 1 AACPCPQSSPPEQK 14 0 Q5THK1-2;Q5THK1-4;Q5THK1;H7C1B0;H3BLU3;H7BZH1 Q5THK1-2 PRR14L Protein PRR14L 1 AACPCPQS(0.936)S(0.064)PPEQK 237.48 5.428199999999999e-27 5812000.0 15340.0 13643.0 18522.0 19664.0 21171.0 17766.0 17920.0 18189.0 15049.0 16423.0 True False 20217.80090817847 18052.832946593946 18276.386177940196 15130.768605771504 18231.77208806072 16655.089211497816 19514.84528436008 15378.30799163907 15844.459416857582 15848.035768772146 1.2757291315569057 1.1391211636565242 1.153227216583711 0.9547409424444898 1.150412098639102 1.0509245091632071 1.2313731221387838 0.9703605049870815 0.9997743346893745 1.0 13.952016421033603 -1.5228803101979118 0.6988919010579157 1.0585242141253248 28.147434929937855 0.3943949920862435 0.08339967646743189 308.42815095280764 1.6447046796966653 0.03290014206604145 13053.13363344063 0.029999891899518415 1.5228803101979118 27.08891071581253 AACPCPQS(ph)SPPEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AACPCPQSSPPEQK 14 0 Q5THK1-2;Q5THK1-4;Q5THK1;H7C1B0;H3BLU3;H7BZH1 Q5THK1-2 PRR14L Protein PRR14L 1 AACPCPQS(0.704)S(0.296)PPEQK 152.16 0.00025051 2469700.0 15233.0 16411.0 15829.0 16782.0 19807.0 16194.0 17011.0 18217.0 19215.0 12513.0 True False 17811.646034535803 18040.175623479405 16206.423391816785 15841.758947978095 15925.9605357392 15344.758132092282 15399.59493102522 17738.82305250698 19495.983023791418 14781.507847146493 1.2049952020269883 1.220455707904115 1.0963985243863579 1.071728210125483 1.077424624092977 1.0381050628102546 1.0418148872408877 1.2000685745961557 1.3189441310992527 1.0 13.851505824449179 -5.2608903926873305 24.81186631716981 1.1058069058556914 1.2127254626711375 0.19395464488295844 0.08738495418456113 73.64089432267406 3328006.0331837223 0.024000902807352287 0.05618164330108921 5.484153566142318e-06 5.2608903926873305 0.10691855681544604 AACPCPQS(ph)SPPEQK ddPTM_PC-9_Lapatinib_30min_R1 3 AACPCPQSSPPEQK 14 0 Q5THK1-2;Q5THK1-4;Q5THK1;H7C1B0;H3BLU3;H7BZH1 Q5THK1-2 PRR14L Protein PRR14L 1 AACPCPQS(0.962)S(0.038)PPEQK;AACPCPQS(0.922)S(0.078)PPEQK;AACPCPQS(0.5)S(0.5)PPEQK 217.2 1.1951999999999997e-74 8419000.0 86508.0 88836.0 94869.0 84261.0 97105.0 93385.0 81750.0 81389.0 90178.0 75450.0 True False 85274.38005637564 88630.30570006739 87069.2370249303 90457.83502645619 91393.47481577535 89391.14124106748 85982.61499417786 85170.63006515242 80021.2040235617 88491.43196919459 0.9636456113181798 1.0015693466337074 0.9839284446797135 1.0222213949249475 1.0327946195693953 1.010167190787308 0.971649040825895 0.9624731815256623 0.9042819428147403 1.0 16.433250155039403 -7.525716414639563 2.645621658297641 0.9498179356771069 1.003607212927643 0.3582427171350052 0.028277962152620777 0.28698501227365103 4.036386763750521 0.015205539524242246 0.008331975703363336 2.9804619745015865e-08 7.525716414639563 0.05378927725053606 AACPCPQSS(ph)PPEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AACPCPQSSPPEQK 14 0 Q5THK1-2;Q5THK1-4;Q5THK1;H7C1B0;H3BLU3;H7BZH1 Q5THK1-2 PRR14L Protein PRR14L 1 AACPCPQS(0.209)S(0.791)PPEQK 161.76 6.9061e-13 0.0 11778.0 11155.0 11106.0 14941.0 13698.0 13348.0 14120.0 11612.0 12120.0 10282.0 True False 13771.78277389633 12262.394679173276 11370.809159739543 14103.904209375558 11013.975231915763 12648.007382188945 12782.451380052677 11307.197303930994 12297.232071212706 12146.04520773279 1.1338491285318544 1.00957920619021 0.9361737886913436 1.1611931264998334 0.9067951784753532 1.041327211110377 1.0523961636430201 0.930936540293153 1.0124474148493752 1.0 13.568199023589125 -4.762811062741673 6.92854753364476 1.0054800073877346 1.1366271926537255 0.23608139521645988 0.06921818801083546 0.1570236616260356 42.62022652363835 0.016321421968469123 0.09744538102619149 1.726588870950398e-05 4.762811062741673 0.1311471852659909 AADAEAEVAS(ph)LNRR ddPTM_PC-9_AZD4547_30min_R2 1 AADAEAEVASLNRR 14 1 J3KN67;A0A494C0P6;A0A2R2Y2Q3;P06753 J3KN67 TPM3 Tropomyosin alpha-3 chain 1 AADAEAEVAS(1)LNRR 92.307 0.0019244 4456400.0 19911.0 15137.0 19931.0 32053.0 29409.0 22138.0 22969.0 28975.0 27155.0 22351.0 True False 26242.283825472066 20029.73922983159 19666.701917315946 24663.676063913455 25326.067986291506 20753.707360359032 25013.196503151034 24497.57952926177 28590.35786196875 21568.498293114917 1.2166949904829079 0.9286571071211513 0.9118252763843989 1.1435045559841586 1.1742156381084758 0.9622231032646357 1.1597096915706797 1.1358036705356473 1.3255608931798162 1.0 14.396638111889462 -7.396558939982515 8.825090089561511 1.167966965440518 1.0532293219112336 0.13460274734374456 0.1214057691318364 0.60381153896707 40.34231670951242 0.05113489055534267 0.03439491933096463 4.01274035932191e-08 7.396558939982515 -0.1147376435292844 AADAEAEVASLNRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AADAEAEVASLNRR 14 1 J3KN67;A0A494C0P6;A0A2R2Y2Q3;P06753 J3KN67 TPM3 Tropomyosin alpha-3 chain 0 116.9 8.7225e-05 7838200.0 21678.0 20719.0 32582.0 36555.0 39812.0 40247.0 32720.0 38782.0 33670.0 21720.0 False True 25347.657239983397 22775.845392899242 33358.8784479231 34506.94186290902 32011.1243928333 38136.376469205745 29620.524727714135 37764.01359292558 34162.36005261815 25657.664064574597 0.9879175741092024 0.8876819548177706 1.3001525923781008 1.3448980303141693 1.2476242697803068 1.4863541892677767 1.1544513426150527 1.4718414543850138 1.3314680544042954 1.0 14.647102209530521 -5.2674427003306485 23.93381502604373 1.3112692763668028 0.9377997487357363 0.5119632414976651 0.13735185737865208 164.70081095065106 656628.4646746815 0.032990463053277276 0.07177407861313595 5.402033830737021e-06 5.2674427003306485 -0.37346952763106644 AADAEAEVASLNRR ddPTM_PC-9_Lapatinib_30min_R1 1 AADAEAEVASLNRR 14 1 J3KN67;A0A494C0P6;A0A2R2Y2Q3;P06753 J3KN67 TPM3 Tropomyosin alpha-3 chain 0 187.74 2.61e-06 9305800.0 60882.0 27538.0 45386.0 35327.0 28612.0 33879.0 24826.0 24834.0 38465.0 23727.0 False True 60013.81151560857 27474.237452929672 41654.53827502644 37925.065427417314 26929.09841335633 32430.074145806328 26111.36880544906 25987.878300974247 34132.666645593126 27828.180335759807 2.1565841097590392 0.987281134498927 1.4968473602098757 1.3628295120210498 0.9676916739953658 1.1653681180200268 0.9383067268647599 0.9338691207049304 1.2265504331855979 1.0 14.764258954535745 -3.302236082637497 1.867348113868367 1.120296199374561 199.99999999990735 0.7089342899005042 0.1948634330461311 154.2664440741306 3.5434954178281624 0.0546313816047618 129319.39317807781 0.000498613367369291 3.302236082637497 198.87970380053278 up AADEEAFEDNSEEYIRR ddPTM_PC-9_AZD4547_30min_R2 2 AADEEAFEDNSEEYIRR 17 1 P55060-4;P55060-3;P55060 P55060-4 CSE1L Exportin-2 0 ; 127.03 2.2269e-05 16980200.0 29780.0 21529.9 39858.0 62249.0 46303.0 31558.0 32637.0 35524.0 30849.0 37634.0 False True 39249.42053751989 28489.019134858365 39329.45687724545 47898.45478746291 39874.62769795831 29584.67327121739 35541.62977375333 30034.582060310433 32479.615160518293 36316.445114898066 1.0807616332860353 0.7844660743837876 1.0829654927076373 1.318919146296441 1.0979771718240279 0.81463571606795 0.9786648902806051 0.8270242851492469 0.8943500680685899 1.0 15.148335368904322 -6.7499844714080375 24.98057758750669 0.8968571257139051 1.071201097852117 0.2936194646432667 0.13172024836554316 308.5422764976141 672860.1435968155 0.04733670152419983 0.04694259700949788 1.778342995164213e-07 6.7499844714080375 0.17434397213821184 AADEEAFEDNSEEYIRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AADEEAFEDNSEEYIRR 17 1 P55060-4;P55060-3;P55060 P55060-4 CSE1L Exportin-2 0 ; 137.93 4.0929e-05 10109200.0 26767.0 18088.1 29568.0 31889.0 35361.0 35051.0 29503.0 27959.0 28732.4 24722.8 False True 31298.124427651823 19883.767027911625 30273.013257264454 30102.36271553291 28432.265891062434 33212.86385624099 26708.26225677721 27225.10587500921 29152.556993639613 29204.847934422884 1.0716756511771341 0.6808378893996987 1.036574931848303 1.0307317053362277 0.9735461028561004 1.1372380342749184 0.9145146832042559 0.9322118689383686 0.9982095116228413 1.0 14.833920252436153 AADGGERPLAAS(ph)PPGTVK ddPTM_PC-9_AZD4547_30min_R2 2 AADGGERPLAASPPGTVK 18 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785;O95785-2 B9EGQ5 WIZ Protein Wiz 1 AADGGERPLAAS(0.946)PPGT(0.054)VK;AADGGERPLAAS(0.852)PPGT(0.148)VK 59.242 0.013875 22373300.0 144120.0 125618.0 141260.0 183977.0 171820.0 154407.0 131381.0 171246.0 143499.0 142231.0 True False 189947.16211777614 166221.56190612324 139386.8001023556 141563.9450663153 147965.75882908644 144751.90588088156 143073.65448127862 144783.86554160356 151084.06418098512 137251.53598174694 1.3839346915799702 1.2110725079843843 1.0155573058278389 1.0314197509974814 1.0780626808341465 1.0546468922586927 1.0424193321982638 1.0548797469258073 1.10078231985016 1.0 17.06646276895581 -4.954215358090605 2.5951149723395344 1.0499701134158903 1.399173529954368 0.9296770637598304 0.029363247237144282 0.08095456591622946 0.9240159346900284 0.007815424883506018 0.05287112250139108 1.1111805780501407e-05 4.954215358090605 0.34920341653847764 AADGGERPLAAS(ph)PPGTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AADGGERPLAASPPGTVK 18 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785;O95785-2 B9EGQ5 WIZ Protein Wiz 1 AADGGERPLAAS(0.997)PPGT(0.003)VK;AADGGERPLAAS(0.968)PPGT(0.032)VK 64.377 0.007548699999999999 17150700.0 86775.0 73735.0 74659.0 74793.0 90610.0 75390.0 92854.0 77030.0 72762.0 51675.0 True False 101464.29361562693 81054.92350236139 76439.15370583418 70602.59069217778 72855.62094932752 71436.41568348996 84058.19691525593 75008.04412003138 73826.00659782003 61043.268440925094 1.6621700673485311 1.3278273849442166 1.252212662560959 1.1565991221538827 1.1935078643410761 1.1702586953158134 1.3770264774829946 1.228768479076784 1.2094045499753259 1.0 15.89754459003897 -4.610128617015019 1.6799247127578896 1.2083013907364135 1.9881421928113157 0.7158138225870647 0.08829855070328976 0.8438632103102741 1.6672200183416785 0.023810595097028882 1.2209813929191864 2.4539820572948264e-05 4.610128617015019 0.7798408020749021 AADGGERPLAAS(ph)PPGTVK ddPTM_PC-9_Lapatinib_30min_R1 2 AADGGERPLAASPPGTVK 18 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785;O95785-2 B9EGQ5 WIZ Protein Wiz 1 AADGGERPLAAS(0.974)PPGT(0.026)VK;AADGGERPLAAS(0.868)PPGT(0.132)VK 54.15 0.020413 19956300.0 82960.0 85056.0 99416.0 83080.0 80044.0 86257.0 72868.0 75513.0 100687.0 74609.0 True False 81776.97518699942 84859.05805782504 91242.40023685773 89189.98034675531 75335.96929255885 82567.98918488783 76640.74849413773 79021.60965375972 89346.56977888559 87505.06623975669 0.9345398923867703 0.9697616572887128 1.042709915639182 1.0192550463579113 0.8609326583005432 0.943579528968738 0.8758435572649974 0.9030518237338053 1.021044536256716 1.0 16.417078925950243 -6.23720358584041 24.96205310014572 0.9267915512414495 0.9936622237151613 0.20673729633625526 0.05398978183803576 1096.9101907902239 1129780.1405578724 0.016029111129149367 0.02068286443467286 5.791571391350787e-07 6.23720358584041 0.06687067247371181 AADIS(ph)LDNLVEGK ddPTM_PC-9_AZD4547_30min_R2 6 AADISLDNLVEGK 13 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 AADIS(1)LDNLVEGK;AADIS(1)LDNLVEGK;AADIS(1)LDNLVEGK;AADIS(1)LDNLVEGK;AADIS(1)LDNLVEGK;AADIS(1)LDNLVEGK 123.68 0.00016299999999999998 5052900.0 45581.899999999994 48515.5 54895.7 75022.9 68144.6 63017.3 56411.5 70164.2 55605.1 62213.899999999994 True False 60075.99603758152 64197.186602688394 54167.74714978684 57727.529497250565 58683.89855141761 59076.8182690376 61432.01421644412 59321.93510291733 58544.27206593848 60035.8102974374 1.0006693628343655 1.0693149019665789 0.9022572841346154 0.9615516008070709 0.9774815774231751 0.9840263332226444 1.0232561851349964 0.9881091769898116 0.9751558574106131 1.0 15.873535679059406 -7.028649622344078 24.0797143322517 0.996782523444976 0.981422782701127 0.028775827336567028 0.04003395452749249 2194.4187262276837 1844377.0605871414 0.01611331433183769 0.012509916620209952 9.361606399712033e-08 7.028649622344078 -0.015359740743848938 AADIS(ph)LDNLVEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AADISLDNLVEGK 13 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 AADIS(1)LDNLVEGK 94.71700000000001 0.014744 0.0 8014.4 7927.1 7027.9 9010.0 9629.6 7646.6 8484.4 5749.6 5268.7 7135.3 True False 9371.079628384678 8714.050099621198 7195.471789459173 8505.198910814126 7742.749006661996 7245.598834930028 7680.6962102633815 5598.679092204763 5345.744770098876 8428.873406996277 1.111783173846974 1.0338333106756845 0.8536694575916474 1.009055243818764 0.9185983265848111 0.8596165211018488 0.9112363941648618 0.6642262639224895 0.6342181821904822 1.0 13.041124099844325 -6.659228476012433 0.7651901733504173 0.7610552143393488 1.0281107074129514 0.3893331208668299 0.1146189783935978 0.6682679129308089 0.8672885605369042 0.07773585532891994 0.08478750807010571 2.191651635950234e-07 6.659228476012433 0.26705549307360266 AADIS(ph)LDNLVEGK ddPTM_PC-9_Lapatinib_30min_R1 4 AADISLDNLVEGK 13 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 AADIS(1)LDNLVEGK;AADIS(1)LDNLVEGK;AADIS(1)LDNLVEGK;AADIS(1)LDNLVEGK 153.09 0.00014350000000000002 1822500.0 28258.700000000004 29526.0 32777.4 25936.3 27462.0 26461.9 29438.2 23885.5 30088.4 23605.9 True False 27855.72575598912 29457.634361072043 30082.56869642294 27843.742022960472 25846.739152369337 25330.18622270174 30962.365953781144 24995.307528304762 26699.52754710163 27686.14836211541 1.0061249904340521 1.0639845592021988 1.0865566529140864 1.0056921482462582 0.9335621125160535 0.9149046624832268 1.1183341773949595 0.9028091304497708 0.9643640999784631 1.0 14.756876742558074 -5.977016171675556 6.6547666160100425 0.9716235477234451 1.052727293100211 0.26641992254526925 0.05935737889887353 0.22383627299825046 36.967655543874066 0.016989236259979765 0.024867515069845733 1.0543476352768566e-06 5.977016171675556 0.0811037453767659 AADKLIQNLDANHDGR ddPTM_PC-9_AZD4547_30min_R2 1 AADKLIQNLDANHDGR 16 1 Q96FQ6 Q96FQ6 S100A16 Protein S100-A16 0 92.575 0.0013478 6396200.0 35300.0 23682.0 42185.0 99329.0 77711.0 38343.0 28662.0 27957.0 34242.0 51704.0 False True 46524.665714387214 31336.74337324912 41625.59933681066 76430.23366775202 66922.16903950134 35945.40614862437 31212.86247434868 23636.88803794896 36051.96221357151 49893.85869747277 0.9324727918216472 0.6280681468887149 0.8342830244740939 1.5318565383202838 1.3412907076455702 0.7204374864364836 0.6255852581698532 0.4737434356654844 0.7225731413593316 1.0 15.606574628539704 -6.922075418404988 9.685918948118323 0.6632426442610269 1.0440354801062959 0.2902146430816612 0.2664743392810516 0.4642880794235627 53.746396083531465 0.10451407463718647 0.09217592921984342 1.196532726627605e-07 6.922075418404988 0.380792835845269 AADPPAENS(ph)SAPEAEQGGAE ddPTM_PC-9_AZD4547_30min_R2 2 AADPPAENSSAPEAEQGGAE 20 0 H0Y449;P67809 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 AADPPAENS(0.647)S(0.353)APEAEQGGAE;AADPPAENS(0.5)S(0.5)APEAEQGGAE 132.51 4.446399999999999e-05 46137000.0 60401.0 55105.0 71089.0 95901.0 84063.0 73200.0 72540.0 84637.0 73338.0 81242.0 True False 79607.26158115308 72916.6136129927 70146.3134112725 73792.50610568015 72392.30348300269 68622.7924283261 78995.9194713994 71558.29641477589 77214.49695750554 78397.7423081404 1.0154279860287136 0.9300856308641612 0.8947491515197483 0.9412580507183551 0.9233978090652983 0.8753159263006056 1.0076300304785293 0.9127596574594937 0.9849071501831758 1.0 16.258524487872727 -8.407636643245922 4.9720591430043815 0.999387537994501 0.9359281838168929 0.21697033112256947 0.041971675878128036 0.3132765621184903 10.639068117545715 0.0394638116763951 0.010283947099577495 3.911680335082553e-09 8.407636643245922 -0.06345935417760806 AADPPAENS(ph)SAPEAEQGGAE ddPTM_PC-9_Lapatinib_30min_R1 1 AADPPAENSSAPEAEQGGAE 20 0 H0Y449;P67809 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 AADPPAENS(0.5)S(0.5)APEAEQGGAE 117.48 1.622e-05 30304000.0 49337.0 39903.0 52138.0 41055.0 50677.0 43337.0 46091.0 46437.0 45140.0 40954.0 True False 48633.445332702286 39810.60705513302 47851.414898500174 44074.32165546517 47696.27849481541 41483.57753348115 48477.36645500499 48594.632546603105 40055.857854726986 48032.84433222521 1.0125039649187322 0.8288205208040137 0.9962228047027538 0.9175871691174393 0.9929930063045631 0.863650239959865 1.0092545450713928 1.0116959181199474 0.8339264187162352 1.0 15.551733621864026 AADPPAENSS(ph)APEAEQGGAE ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AADPPAENSSAPEAEQGGAE 20 0 H0Y449;P67809 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 AADPPAENS(0.041)S(0.959)APEAEQGGAE;AADPPAENS(0.218)S(0.782)APEAEQGGAE 145.04 1.4194000000000002e-05 22457000.0 65482.0 72847.0 86955.0 88435.0 92227.0 82352.0 81681.0 84746.0 77577.0 57995.0 True False 76566.80927154695 80078.76873094884 89028.33697867388 83480.27366013854 74155.78140705917 78033.31614758943 73943.58436077066 82521.50729580928 78711.41686373494 68509.03441183247 1.1176162374625849 1.1688789576213632 1.2995123598369887 1.2185294155265503 1.08242339194685 1.1390222737413445 1.0793260333559682 1.2045346720221275 1.1489202488327637 1.0 16.064006631005213 -6.251249819587934 24.45918448985965 1.1192781416091664 1.2058573081422646 0.3095373883826942 0.0661850578600232 720.2495199012816 1728897.7836746976 0.019985341582476043 0.025495908305334193 5.607253367281513e-07 6.251249819587934 0.08657916653309816 AADPPAENSS(ph)APEAEQGGAE ddPTM_PC-9_Lapatinib_30min_R1 1 AADPPAENSSAPEAEQGGAE 20 0 H0Y449;P67809 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 AADPPAENS(0.23)S(0.77)APEAEQGGAE 146.1 0.00017254 11629000.0 56686.0 44207.0 56078.0 47633.0 45825.0 48930.0 43785.0 45021.0 55720.0 42627.0 True False 55877.647245060776 44104.641407569965 51467.48330733998 51136.08971902989 43129.66359541637 46837.37796140097 46051.97305834961 47112.84001724095 49444.22684238787 49995.020153092795 1.1176642608394682 0.8821806906470776 1.0294521964335301 1.022823664485842 0.8626791921144626 0.9368408657097723 0.9211312030144415 0.9423506555847734 0.9889830365300722 1.0 15.609496779272146 -4.7456785128137575 24.96105979609149 0.9523313258808136 1.1176647273402571 0.45519506308360724 0.05366944361927425 840.0332770024005 1330317.4700877925 0.013498848533604555 0.3357409377204031 1.7960626731297198e-05 4.7456785128137575 0.16533340145944353 AADPPAENSSAPEAEQGGAE ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AADPPAENSSAPEAEQGGAE 20 0 H0Y449;P67809 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 122.97 0.00020201 0.0 6994.7 8082.6 7690.2 8756.1 8087.0 8287.4 7619.5 9083.9 7258.2 4992.0 False True 8178.764558377708 8884.987111957504 7873.563533245909 8265.524104659215 6502.410403015242 7852.794154866095 6897.725799597123 8845.457250187632 7364.337443834654 5897.0100833497445 1.3869341314966572 1.5066935593419344 1.3351789164269836 1.4016465951104593 1.1026622493617317 1.3316568979657204 1.1696988307808576 1.499990185732063 1.2488256488873777 1.0 12.525767945701046 -14.522878744114946 0.12003790418174501 1.4781317675544606e-08 1.4824572161368184 0.4354259898501799 0.11912631517474928 160.43329703443942 1.2437253674859028 39.64169479479997 1.1837101588734327 3.0000000080502394e-15 14.522878744114946 1.4824572013555006 AADPPAENSSAPEAEQGGAE ddPTM_PC-9_Lapatinib_30min_R1 1 AADPPAENSSAPEAEQGGAE 20 0 H0Y449;P67809 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 154.1 3.8339e-15 0.0 6255.3 8655.5 8630.4 5258.8 7496.6 5183.3 8015.8 6485.6 7553.4 9142.9 False True 6166.098274918473 8635.45872154234 7920.841826307404 5645.549694842539 7055.664726882675 4961.622341862449 8430.81890238938 6786.944652846847 6702.6565511717945 10723.238082851536 0.5750220434608477 0.8053032726515748 0.7386613786906692 0.5264780704506439 0.6579789306521137 0.46269814243861757 0.7862195017260538 0.6329193290691215 0.6250590073058805 1.0 13.38845299995963 -10.919557004087675 3.129046254199567 1.0045509581001923 0.6482728714764645 0.5127408282357545 0.10361677577654264 40918174.09793993 52753478.193112925 1676130.5126307795 0.026999407010353235 1.2034914130370853e-11 10.919557004087675 -0.35627808662372784 AADPVPSFDESS(ph)QDTSEK ddPTM_PC-9_AZD4547_30min_R2 2 AADPVPSFDESSQDTSEK 18 0 A0A075B754;Q96QE3;Q96QE3-2 A0A075B754 ATAD5 ATPase family AAA domain-containing protein 5 1 AADPVPSFDES(0.036)S(0.963)QDT(0.001)SEK;AADPVPSFDES(0.004)S(0.995)QDT(0.001)SEK 207.43 4.0189999999999993e-67 0.0 26027.0 35311.0 29717.0 28089.0 19565.0 25934.0 25120.0 28619.0 25061.0 24899.0 True False 34303.04460476931 46724.590205759625 29322.933163257137 21613.515020723957 16848.737466482817 24312.342880276057 27355.63133611189 24196.591149195578 26385.673296954494 24027.293588665776 1.4276699320372412 1.9446464094399996 1.220401001679583 0.8995401392572797 0.701233262260996 1.0118635621843297 1.1385232063346562 1.007046052020177 1.0981541970004154 1.0 14.55238653338122 -5.46550710319063 4.65171223000416 0.9797971864268223 1.6794233913021144 0.7485462918070442 0.16188574441314305 0.09847322075205031 4.377645757618697 0.04405415144886317 0.09269312131032353 3.423677879155367e-06 5.46550710319063 0.699626204875292 AADPVPSFDESS(ph)QDTSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AADPVPSFDESSQDTSEK 18 0 A0A075B754;Q96QE3;Q96QE3-2 A0A075B754 ATAD5 ATPase family AAA domain-containing protein 5 1 AADPVPSFDES(0.148)S(0.851)QDTSEK 203.56 1.0295e-54 0.0 8895.6 13402.0 9465.3 9105.8 10831.0 6366.2 11460.0 7336.7 6546.1 5257.9 True False 10401.449383891342 14732.461989267616 9690.98864935015 8595.631547401916 8708.743300984057 6032.345264945405 10374.425836784965 7144.119398876214 6641.8243284955 6211.115648486499 1.674650734675328 2.3719510025316577 1.5602653690261934 1.3839110449499465 1.4021222263195454 0.9712176694722057 1.6702998984269382 1.1502151631353164 1.0693448173218212 1.0 12.600636715100812 -5.556440007564948 2.81260944625581 1.2514487695657703 2.0248594085188123 0.5930449278437624 0.25741584790108835 0.1706044657999992 2.7191050740970706 0.0694376574302772 0.14721317133345407 2.776898413935257e-06 5.556440007564948 0.773410638953042 AADPVPSFDESS(ph)QDTSEK ddPTM_PC-9_Lapatinib_30min_R1 1 AADPVPSFDESSQDTSEK 18 0 A0A075B754;Q96QE3;Q96QE3-2 A0A075B754 ATAD5 ATPase family AAA domain-containing protein 5 1 AADPVPSFDES(0.146)S(0.854)QDTSEK 197.49 5.6502e-54 0.0 15052.0 27617.0 23384.0 15488.0 11302.0 15431.0 22797.0 22054.0 16081.0 11250.0 True False 14837.355719801268 27553.054533283437 21461.457784850358 16627.03918645341 10637.238580586933 14771.052101417907 23977.31711342232 23078.709352085276 14269.788439562797 13194.54751031726 1.1245065970014843 2.0882151897773515 1.626539884605283 1.260144705489307 0.8061844161210772 1.1194815199132768 1.8172140495665843 1.7491095722713688 1.0814913075575172 1.0 13.687654255729754 -5.735641901188984 7.116987094781037 1.2911927864656438 1.6632595439733169 0.15374842319920878 0.36778562622704586 0.33972837710866255 62.31514969126192 0.10654200783942717 0.1804513419026105 1.8380532910111778e-06 5.735641901188984 0.37206675750767304 AADRLPNLS(ph)SPSAEGPPGPPSGPAPR ddPTM_PC-9_AZD4547_30min_R2 3 AADRLPNLSSPSAEGPPGPPSGPAPR 26 1 O60784-4;O60784;O60784-2;O60784-3 O60784-4 TOM1 Target of Myb protein 1 1 AADRLPNLS(0.471)S(0.407)PS(0.121)AEGPPGPPS(0.001)GPAPR;AADRLPNLS(0.539)S(0.363)PS(0.099)AEGPPGPPSGPAPR;AADRLPNLS(0.492)S(0.492)PS(0.015)AEGPPGPPSGPAPR 71.634 9.4335e-05 169811400.0 11764.6 13060.0 29970.0 40963.8 29296.6 21354.8 12169.900000000001 18890.6 14953.0 35310.6 True False 15505.498081118418 17281.389597780315 29572.578217949875 31520.22879440108 25229.272786126265 20019.48098016962 13252.997523779784 15971.491832803184 15743.385052845475 34074.38664171017 0.4550484868343388 0.5071665641260967 0.8678829212365141 0.9250417073044959 0.7404175180439881 0.5875228567038664 0.3889430986134583 0.4687242649660087 0.4620298882672808 1.0 15.056400067484491 -6.9027931353740986 4.972072105797235 0.5296989917414214 0.7094048998697557 0.052423388533071935 0.20684215240779494 0.4457416815167697 18.213480867417722 0.07640375958133036 0.06710767570869834 1.2508546997091082e-07 6.9027931353740986 0.1797059081283343 AADRLPNLS(ph)SPSAEGPPGPPSGPAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AADRLPNLSSPSAEGPPGPPSGPAPR 26 1 O60784-4;O60784;O60784-2;O60784-3 O60784-4 TOM1 Target of Myb protein 1 1 AADRLPNLS(0.618)S(0.376)PS(0.005)AEGPPGPPSGPAPR;AADRLPNLS(0.468)S(0.468)PS(0.064)AEGPPGPPSGPAPR 118.59 3.535e-12 95280300.0 19458.0 13597.3 12057.2 29018.3 32559.0 22523.2 23940.9 27486.0 29551.0 24290.0 True False 22751.855086982057 14947.150082574879 12344.689375185642 27392.49872959793 26179.297676737133 21342.043742172475 21673.044634893988 26764.521623824272 29983.127470000563 28693.584720465806 0.7929248056188049 0.5209230644477045 0.430224717317413 0.9546558576231198 0.9123745928498314 0.743791476390546 0.7553271871058902 0.9327702301599973 1.0449418489218947 1.0 14.808440596362026 -6.527211005217035 0.3996469106503568 1.0173127427747495 0.5434348514741113 0.43111570556707013 0.14571179881423166 1.7074855921756775 0.5257954027740614 0.1608506875971019 0.33177502659350977 2.970222576291416e-07 6.527211005217035 -0.4738778913006382 AADRLPNLS(ph)SPSAEGPPGPPSGPAPR ddPTM_PC-9_Lapatinib_30min_R1 1 AADRLPNLSSPSAEGPPGPPSGPAPR 26 1 O60784-4;O60784;O60784-2;O60784-3 O60784-4 TOM1 Target of Myb protein 1 1 AADRLPNLS(0.478)S(0.478)PS(0.044)AEGPPGPPSGPAPR 77.89399999999999 2.6155999999999998e-05 10136000.0 11509.0 7532.3 11637.0 10328.0 15076.0 18165.0 16222.0 13411.0 15499.0 14878.0 True False 11344.879549507883 7514.859422133131 10680.250780119039 11087.555573198013 14189.259320556408 17388.12529468319 17061.89578514439 14034.12401926253 13753.339408294505 17449.64247631115 0.6501496844367546 0.43065979330722487 0.6120612955032212 0.6354030226263936 0.8131547302369724 0.9964745878483485 0.9777791039734396 0.8042642729393812 0.7881731346052173 1.0 14.090909857076817 -6.236122692817918 2.159065519737263 0.9057720228788546 0.5534935005990889 0.766389281437166 0.08690586652908046 0.15667892229928848 1.4340291732890944 0.030478202541908306 0.039993305948773004 5.806003685600376e-07 6.236122692817918 -0.35227852227976575 AADRLPNLSS(ph)PSAEGPPGPPSGPAPR ddPTM_PC-9_AZD4547_30min_R2 2 AADRLPNLSSPSAEGPPGPPSGPAPR 26 1 O60784-4;O60784;O60784-2;O60784-3 O60784-4 TOM1 Target of Myb protein 1 1 AADRLPNLS(0.101)S(0.836)PS(0.063)AEGPPGPPSGPAPR;AADRLPNLS(0.099)S(0.884)PS(0.017)AEGPPGPPSGPAPR 107.19 3.5141000000000003e-10 158310900.0 18246.8 14844.8 26394.2 48126.7 34305.2 27038.1 20731.1 26747.1 19455.8 26013.6 True False 24048.90284298247 19643.091294114016 26044.195662336075 37031.83286510291 29542.515130855427 25347.403332736652 22576.127738537776 22613.95028221285 20484.19386819708 25102.871781923597 0.9580140093891535 0.7825037495613896 1.0374986530859915 1.4752030439708206 1.1768579861101305 1.0097411783375774 0.8993444230071991 0.9008511248699839 0.8160099787048112 1.0 14.615564798249158 -7.1049984383454445 3.6080612545727697 0.8961470804630772 1.088449179391205 0.20088656185350406 0.16988594280883568 0.4541329063534545 10.814595365491567 0.0778245267546314 0.05969956543936602 7.852384581988157e-08 7.1049984383454445 0.19230209892812777 AADRLPNLSS(ph)PSAEGPPGPPSGPAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AADRLPNLSSPSAEGPPGPPSGPAPR 26 1 O60784-4;O60784;O60784-2;O60784-3 O60784-4 TOM1 Target of Myb protein 1 1 AADRLPNLS(0.34)S(0.642)PS(0.017)AEGPPGPPSGPAPR;AADRLPNLS(0.287)S(0.701)PS(0.012)AEGPPGPPSGPAPR;AADRLPNLS(0.087)S(0.894)PS(0.019)AEGPPGPPSGPAPR 96.61 1.9122e-09 114516000.0 24546.3 12674.2 20827.3 35733.2 41349.1 43019.0 41652.5 38624.2 37396.3 33861.0 True False 28701.50377847608 13932.410815130248 21323.9018199751 33731.18465259746 33247.040681997976 40763.00790937864 37706.87366201446 37610.35567572268 37943.150140651145 39999.73125647147 0.7175424153339162 0.348312610547256 0.5331011271863272 0.8432852820014927 0.8311816014168598 1.0190820445270787 0.9426781750168371 0.9402652091478186 0.94858512666913 1.0 15.28770268664299 -5.869150688614467 2.4289126359317064 0.9462646072354726 0.5053386893244928 0.7872388830803345 0.09603404147208353 0.11927940686383327 1.430270826245368 0.028325144389861067 0.04781507834077842 1.3516035114165778e-06 5.869150688614467 -0.4409259179109798 AADRLPNLSS(ph)PSAEGPPGPPSGPAPR ddPTM_PC-9_Lapatinib_30min_R1 3 AADRLPNLSSPSAEGPPGPPSGPAPR 26 1 O60784-4;O60784;O60784-2;O60784-3 O60784-4 TOM1 Target of Myb protein 1 1 AADRLPNLS(0.022)S(0.913)PS(0.065)AEGPPGPPSGPAPR;AADRLPNLS(0.183)S(0.508)PS(0.31)AEGPPGPPSGPAPR;AADRLPNLS(0.027)S(0.973)PS(0.001)AEGPPGPPSGPAPR 130.62 2.5932e-12 260055800.0 53820.7 40762.1 68900.3 45082.7 65941.0 70970.5 68259.6 61555.7 83335.2 64302.3 True False 53053.20694849241 40667.71786186595 63235.583296849385 48398.232149478514 62062.48002499404 67935.25715531585 71793.7480912121 64415.80254213096 73949.1122174401 75416.86687757095 0.703466069925937 0.5392390263027563 0.8384806465044984 0.6417428110351823 0.8229257272878234 0.900796598532786 0.9519587734632294 0.8541299209194313 0.9805381114212347 1.0 16.20259959587254 -6.39811432351915 0.6852006194678029 0.9643145178871042 0.6259396021375859 0.7054312982360446 0.07821894826682307 0.4283317671526158 0.4419835527629004 0.05012121469506884 0.07800436928172626 3.998394823086514e-07 6.39811432351915 -0.3383749157495183 AADS(ph)DDGAVSAPAASDGGVSK ddPTM_PC-9_Lapatinib_30min_R1 3 AADSDDGAVSAPAASDGGVSK 21 0 Q96GM8 Q96GM8 TOE1 Target of EGR1 protein 1 1 AADS(1)DDGAVSAPAASDGGVSK;AADS(1)DDGAVSAPAASDGGVSK;AADS(1)DDGAVSAPAASDGGVSK 301.38 1.1009999999999996e-132 21528800.0 111619.0 109315.0 122499.0 96607.0 114427.0 123372.0 96099.0 102609.0 138073.0 79874.0 True False 110027.29259158211 109061.88783379347 112427.60507981446 103711.80105150458 107696.62883213763 118095.66715417858 101074.53600398166 107376.58873257088 122521.7647668524 93680.11447458489 1.1744999801578184 1.164194647343024 1.2001224134959367 1.1070844824772417 1.1496210208128577 1.2606268450517057 1.0789326696585415 1.1462047130792288 1.30787377293494 1.0 16.515455218324263 -10.89583079016095 3.7938036905583044 0.9992787887209742 1.1727726008040034 0.4042699945884255 0.06415448717818256 45590526.98164409 299.9452848750613 287568.20007517596 0.01512198031845634 1.271069242810239e-11 10.89583079016095 0.17349381208302916 AAEAGGAEEQYGFLT(ph)TPTK ddPTM_PC-9_AZD4547_30min_R2 1 AAEAGGAEEQYGFLTTPTK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 AAEAGGAEEQY(0.006)GFLT(0.67)T(0.238)PT(0.085)K 69.081 0.016755000000000003 17598000.0 21105.0 20968.0 23082.0 40891.0 35284.0 31491.0 25232.0 34532.0 31475.0 30283.0 True False 27815.95098872926 27745.495948411757 22775.917598489123 31464.211709652278 30385.42564617327 29521.86279180896 27477.59911913914 29195.872866418187 33138.70424251397 29222.80138742783 0.9518577846098005 0.9494468234092152 0.7793885773144161 1.0767007342146446 1.0397848325125196 1.010233837626183 0.9402794329964715 0.9990785099398024 1.1340016243880997 1.0 14.834806865494624 -5.782392699145207 24.99999530143988 1.0245672329194315 0.8991525448160447 0.46882979802611713 0.06568050593596712 219.6813775401971 262107.2739274407 0.018950698489940267 0.028141333143320076 1.6504687311838596e-06 5.782392699145207 -0.12541468810338685 AAEAGGAEEQYGFLT(ph)TPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 AAEAGGAEEQYGFLTTPTK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 AAEAGGAEEQYGFLT(0.867)T(0.133)PTK;AAEAGGAEEQYGFLT(0.895)T(0.105)PTK;AAEAGGAEEQYGFLT(0.905)T(0.094)PT(0.001)K;AAEAGGAEEQYGFLT(0.594)T(0.399)PT(0.007)K;AAEAGGAEEQYGFLT(0.91)T(0.09)PTK;AAEAGGAEEQYGFLT(0.5)T(0.5)PTK 235.02 3.9473e-43 145564600.0 340734.0 319241.0 356422.0 384998.0 402865.0 394375.0 391650.0 403441.0 350187.0 309126.0 True False 398413.5363967394 350933.13668973127 364920.4522179631 363427.8102403572 323926.4952406002 373693.2807424907 354550.07669954887 392851.1012310728 355307.8223862838 365168.0967599305 1.0910414681123286 0.9610180621020746 0.9993218341247095 0.9952342865244402 0.8870613235787588 1.023345916738627 0.970922925210079 1.0758089348899 0.9729979851440059 1.0 18.478201202911308 AAEAGGAEEQYGFLT(ph)TPTK ddPTM_PC-9_Lapatinib_30min_R1 2 AAEAGGAEEQYGFLTTPTK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 AAEAGGAEEQYGFLT(0.5)T(0.5)PTK;AAEAGGAEEQYGFLT(0.898)T(0.102)PTK 218.05 1.6012000000000003e-27 115924500.0 698956.0 602791.0 726442.0 677577.0 713057.0 621386.0 601558.0 523576.0 674562.0 533836.0 True False 688988.7592671692 601395.2744748674 666716.7429072127 727408.2729106104 671116.3891840004 594810.7693015143 632703.7297940997 547903.2523681591 598585.7241072296 626108.8413082439 1.1004296917889527 0.9605283215906392 1.0648575757437304 1.161792047834212 1.0718845429202277 0.9500117712100458 1.0105331342583757 0.8750926615623642 0.9560410021626508 1.0 19.256053948154516 -6.7607805311353975 24.998053651508567 0.9537913300103584 1.0703141525029654 0.49383122489800446 0.05738294296919861 15.990720419862198 606730.996066119 0.02048813223726287 0.019339888372819664 1.7346803896332793e-07 6.7607805311353975 0.11652282249260693 AAEAGGAEEQYGFLTT(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 5 AAEAGGAEEQYGFLTTPTK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 AAEAGGAEEQYGFLT(0.102)T(0.885)PT(0.012)K;AAEAGGAEEQYGFLT(0.112)T(0.887)PT(0.001)K;AAEAGGAEEQYGFLT(0.052)T(0.945)PT(0.003)K;AAEAGGAEEQYGFLT(0.009)T(0.99)PT(0.001)K;AAEAGGAEEQYGFLT(0.083)T(0.917)PTK 231.06 2.1134e-35 559431000.0 469325.0 370224.0 499280.0 624677.0 612050.0 522534.0 464411.0 558259.0 478535.0 521302.0 True False 618560.5874335624 489891.66787508567 492659.22097624384 480667.36881344207 527077.4222520208 489859.8663762706 505742.6793166832 471992.8990656131 503829.3831514349 503051.3756519799 1.2296171273398802 0.9738402310105234 0.9793417627329469 0.9555035371694849 1.047760622001882 0.9737770138117355 1.0053499578670573 0.9382598317197455 1.0015465766263867 1.0 18.94034622161149 -4.759824608855318 24.999631625797647 0.9851915909339696 1.2296174290741226 0.866957082990296 0.028610068907728377 13.37214699214918 206960.6729884384 0.006877015543468816 0.042437312866555596 1.7385027866229856e-05 4.759824608855318 0.24442583814015306 AAEAGGAEEQYGFLTT(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AAEAGGAEEQYGFLTTPTK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 AAEAGGAEEQYGFLT(0.218)T(0.747)PT(0.035)K;AAEAGGAEEQYGFLT(0.011)T(0.89)PT(0.098)K;AAEAGGAEEQYGFLT(0.021)T(0.979)PTK 202.84 4.6991e-16 296181000.0 475029.0 497366.0 545443.0 566774.0 615545.0 576507.0 566076.0 570961.0 510960.0 405820.0 True False 555442.0274495847 546741.2095026177 558448.4297240978 535019.4902861009 494933.37597675534 546273.9580374298 512453.18324466754 555973.8787331865 518431.82335864985 479391.9535306466 1.1586386115971308 1.1404889161696485 1.164909893900414 1.1160376938865288 1.0324190306734367 1.1395142409341827 1.068964924151376 1.1597480404886358 1.081436222574202 1.0 18.870846168365752 -14.522878745280307 0.10224687177000433 0.6437467909842549 1.1913120028219708 0.4959808694059479 0.03899401550359064 169.06896910988735 1.165917641447201 12.938325273537856 0.6366475620011268 3.0000000000002097e-15 14.522878745280307 0.5475652118377159 AAEAGGAEEQYGFLTT(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 4 AAEAGGAEEQYGFLTTPTK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 AAEAGGAEEQY(0.001)GFLT(0.182)T(0.485)PT(0.332)K;AAEAGGAEEQYGFLT(0.004)T(0.996)PT(0.001)K;AAEAGGAEEQYGFLT(0.242)T(0.734)PT(0.024)K;AAEAGGAEEQYGFLT(0.005)T(0.995)PTK 182.28 3.6272e-09 312858000.0 418832.0 357661.0 479576.0 394871.0 402034.0 369008.0 343623.0 353402.0 390691.0 320766.0 True False 412859.37887561833 356832.8579291263 440147.1124968957 423911.13059104205 378387.15054925554 353226.38803966175 361414.11757974775 369822.3470774307 346687.26542138134 376209.9757061723 1.0974174145718825 0.9484938756855827 1.169950668295568 1.1267939660433814 1.0057871268272367 0.9389075538909654 0.9606712764629601 0.9830211077822921 0.9215259770042653 1.0 18.52117857877642 -6.477981787762995 4.854613512741043 0.9605087298283858 1.081282835545821 0.5198309103420871 0.05652227736727219 0.17937250542976954 9.684514523680582 0.018640483639599116 0.020578007852156827 3.326735037398714e-07 6.477981787762995 0.1207741057174353 AAECNIVVTQPR ddPTM_PC-9_Lapatinib_30min_R1 2 AAECNIVVTQPR 12 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 0 ; 103.43 0.0096655 8551200.0 22153.9 20074.2 22522.7 17336.0 19979.9 20202.2 16935.4 14029.9 14335.9 15125.6 False True 21837.981323472308 20027.719423255185 20670.970546136214 18610.947271200694 18804.721563994768 19338.19899962834 17812.232146451395 14681.780372668061 12721.239978280482 17740.03980640488 1.2309995671818 1.128955720608043 1.165215567254429 1.0490927570794617 1.0600157479469408 1.090087689242189 1.00406945761308 0.8276069576443306 0.7170919635528437 1.0 14.114721626417202 -7.549031506281408 2.248994759585619 0.8260030304669992 1.1190488120354323 0.6877714280854615 0.08168944384795228 0.17125616630629248 1.7260625391827034 0.047314556022735724 0.024420672864302037 2.8246750489061095e-08 7.549031506281408 0.2930457815684331 AAEDDEDDDVDTK ddPTM_PC-9_AZD4547_30min_R2 1 AAEDDEDDDVDTK 13 0 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 0 282.61 6.365499999999997e-82 50311000.0 65067.0 65477.0 74539.0 89557.0 91019.0 72110.0 68139.0 70081.0 70584.0 76602.0 False True 85756.95252232395 86641.15977747794 73550.56415708258 68911.01729185712 78382.58295230249 67600.95030063645 74203.2389972664 59251.59175117142 74314.92613990797 73920.18729583434 1.1601289939799253 1.1720906419072408 0.9949996996453417 0.9322354259746375 1.0603677536504241 0.9145127031414597 1.0038291529254282 0.8015617102543577 1.0053400682345928 1.0 16.173680791747536 -5.323531660758119 3.7229661634371305 0.9560366492483362 1.1695024561699878 0.599547773611109 0.06638316568490628 0.14136158341089106 3.8942607134448477 0.017364870223719867 0.04195380081050075 4.747536793820612e-06 5.323531660758119 0.21346580692165162 AAEDDEDDDVDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AAEDDEDDDVDTK 13 0 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 0 ;; 158.08 9.3731e-06 82280000.0 175784.0 205216.0 101307.0 138881.0 137399.0 98750.0 133352.0 101457.0 119754.0 107822.0 False True 205540.7593077431 225588.48825470425 103722.54308893676 131099.9478282772 110476.65227697442 93571.37616056019 120719.93317512669 98793.86125257738 121505.17569769021 127369.27508151754 1.613738942741058 1.7711374121453192 0.8143450845783126 1.029290209466702 0.8673728590059755 0.7346463744939556 0.9477947730947263 0.7756490816906069 0.9539598589999492 1.0 16.95865777688585 -5.261870635210421 24.999999987211627 0.8829974148852245 1.6924382386559724 0.915303609662314 0.09757137194328697 8.4871114217511 492036.58522832993 0.024261110612497687 0.056050049563043824 5.471789286887946e-06 5.261870635210421 0.8094408237707479 AAEDDEDDDVDTK ddPTM_PC-9_Lapatinib_30min_R1 3 AAEDDEDDDVDTK 13 0 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 0 ;; 248.98 1.1185999999999998e-33 224297000.0 75102.2 119891.7 84659.0 74392.4 84235.0 74662.2 89631.5 88018.8 82720.5 67186.0 False True 74031.22885594332 119614.09813477438 77698.66381319046 79863.4652617715 79280.4629123818 71469.07175208893 94272.18049970228 92108.47477642717 73403.64620451807 78799.01058028247 0.9394943960688237 1.5179644674968151 0.9860360332066487 1.0135084777543564 1.0061098778849364 0.9069793037474042 1.1963624899027805 1.1689039506731456 0.9315300492222873 1.0 16.265889894511794 AAEDDEDDDVDTKK ddPTM_PC-9_AZD4547_30min_R2 2 AAEDDEDDDVDTKK 14 1 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 0 ; 137.62 4.692100000000001e-05 29543000.0 79997.0 66743.0 83365.0 99379.0 100028.0 97333.0 79889.0 95505.0 86359.0 79792.0 False True 105434.38195903206 88316.36951949866 82259.52563027668 76468.70694024449 86140.83880896194 91246.75212330937 86998.9662345002 80746.89673657117 90923.7604346073 76998.50636679457 1.3693042493159375 1.1469880869998914 1.068326250881029 0.993119354497264 1.1187338933383517 1.1850457421685692 1.129878621541915 1.0486813387252027 1.1808509635430795 1.0 16.23254283992688 -4.772337319641286 3.232315682141326 1.0949733323155906 1.4116107574486845 0.6367214944829236 0.06292690885514071 0.22817767391066823 3.6101793160805578 0.016355708922624883 0.18634774177735453 1.6891284638059248e-05 4.772337319641286 0.3166374251330939 AAEDDEDDDVDTKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AAEDDEDDDVDTKK 14 1 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 0 ;; 250.48 1.2536999999999997e-124 52175300.0 81646.0 73727.0 61293.0 97271.0 83837.0 69454.0 95288.0 80998.0 76443.0 69626.0 False True 95467.05521799457 81046.12931523137 62754.45757499691 91821.22122683676 67409.74167893999 65811.70997322087 86261.6308146216 78871.888324475 77560.8342590523 82248.64264088716 1.160712835527529 0.9853795359164018 0.7629847199909975 1.1163858548735601 0.8195848528864291 0.8001555753396079 1.0487909349611506 0.958944558742985 0.9430044286286559 1.0 16.327704249626272 -4.8132637126623585 4.075987840525074 0.9288595697879787 1.1731416531951584 0.2950101259761614 0.10595408094870343 0.25622281017412096 7.690074101804358 0.026025815833056926 0.16863859962513855 1.5372209242569446e-05 4.8132637126623585 0.24428208340717972 AAEDDEDDDVDTKK ddPTM_PC-9_Lapatinib_30min_R1 6 AAEDDEDDDVDTKK 14 1 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 0 ;;;;; 223.08 6.0726e-20 624822800.0 625700.0 659684.0 610435.0 635440.0 647595.0 589287.0 539077.0 586257.0 576221.0 549137.0 False True 616777.4032606729 658156.5422288651 560247.390647244 682172.3773656981 609504.7353207571 564084.5687050904 566987.7693359816 613496.640456401 511320.9231038688 644054.598770942 0.9576476970084175 1.0218955714078186 0.8698756156952713 1.0591840795291219 0.9463556917129126 0.8758334616064237 0.8803411549548313 0.9525537766940022 0.7939092804858926 1.0 19.29682347028789 -6.573414693688653 6.092706993659824 0.8971777456625719 0.9762695714908013 0.22261962735976615 0.06759638485839674 0.2790515775406227 23.252503685327063 0.021095605635683887 0.021211930145868453 2.6704552598996496e-07 6.573414693688653 0.07909182582822938 AAEDSPYWVS(ph)PAYSK ddPTM_PC-9_AZD4547_30min_R2 1 AAEDSPYWVSPAYSK 15 0 Q9NW82 Q9NW82 WDR70 WD repeat-containing protein 70 1 AAEDS(0.003)PY(0.001)WVS(0.997)PAYSK 112.5 0.00031192 10633000.0 42037.0 44059.0 57575.0 70895.0 65976.0 51641.0 45476.0 68724.0 53413.0 61160.0 True False 55403.89157608203 58300.21012929576 56811.517881163294 54551.25306683134 56816.371228656855 48411.88010643698 49523.27590131463 58104.284920413695 56236.30213519929 59018.80701565516 0.9387497710922172 0.9878242729276315 0.9626002414127691 0.9243028760706944 0.9626824753266515 0.8202788662535213 0.8391100804219614 0.9845045648754154 0.9528539287532906 1.0 15.848887138509932 -5.949129068673259 1.917885397908049 0.9159398899940391 0.9659873878234889 0.06397996343405754 0.056201247082998854 0.8003361933061305 5.957777182349074 0.019225945426850712 0.032310905786878376 1.124270800471188e-06 5.949129068673259 0.05004749782944984 AAEDSPYWVS(ph)PAYSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AAEDSPYWVSPAYSK 15 0 Q9NW82 Q9NW82 WDR70 WD repeat-containing protein 70 1 AAEDS(0.006)PY(0.021)WVS(0.973)PAYSK;AAEDSPYWVS(0.99)PAYS(0.01)K 129.01 1.6362e-05 11559200.0 53575.0 49525.0 56415.0 57910.0 58230.0 47221.0 53106.0 43417.0 42326.0 35192.0 True False 62644.18934551669 54441.51470067742 57760.14755507893 54665.49044675317 46820.24950755254 44744.64763218042 48075.41522585532 42277.34975411403 42944.937677075 41572.03102028129 1.506883060751955 1.309570722539816 1.389399221964886 1.3149583771859525 1.1262439760210623 1.0763161321214096 1.1564365282610631 1.0169661841512783 1.0330247674481896 1.0 15.343325612748922 -6.067197777784093 0.5933049523936202 1.0142069461048018 1.4962208784839874 0.8887485020995132 0.05569235091041113 0.3620532210012066 0.24446462926090606 0.03875800246050794 0.09955008578672607 8.566476389003911e-07 6.067197777784093 0.48201393237918566 AAEDSPYWVS(ph)PAYSK ddPTM_PC-9_Lapatinib_30min_R1 1 AAEDSPYWVSPAYSK 15 0 Q9NW82 Q9NW82 WDR70 WD repeat-containing protein 70 1 AAEDSPYWVS(1)PAYSK 186.85 3.4899e-07 7982100.0 39643.0 33457.0 42503.0 31136.0 26992.0 32316.0 28682.0 26681.0 30902.0 21207.0 True False 39077.68355036416 33379.53237209196 39008.56740632462 33425.84530665119 25404.383628313797 30933.920012275375 30167.01361789616 27920.696663779254 27421.491347513806 24872.601693448734 1.5711136306523554 1.3420201386043138 1.5683348242817396 1.3438821446433291 1.0213802295963728 1.2436945838449682 1.212861203250882 1.1225482966316855 1.1024778061209588 1.0 14.60226980201873 -4.986483624532394 0.30661354394496243 1.023300097156247 1.9107752537417086 0.7086889318500815 0.10463645102201284 4.019100996226768 0.340505503888558 0.1254712629449572 1.326961793105733 1.0316119765720498e-05 4.986483624532394 0.8874751565854617 AAEEAFVNDIDESSPGTEWER ddPTM_PC-9_Lapatinib_30min_R1 2 AAEEAFVNDIDESSPGTEWER 21 0 P09496-2;P09496-5 P09496-2 CLTA Clathrin light chain A 0 ; 240.5 6.318899999999999e-51 3777900.0 10028.2 8032.5 11542.0 6894.400000000001 11689.0 9960.7 7600.3 6293.9 10810.8 11036.9 False True 9885.196029053344 8013.90123976533 10593.061313408427 7401.437175044186 11001.476001458203 9534.704080525788 7993.806345446491 6586.337571011584 9593.173861229121 12944.613459255166 0.7636532415717371 0.6190915831507919 0.8183373993168238 0.5717773804788502 0.849888336649585 0.7365769638882994 0.6175392081507898 0.5088091345286537 0.7410938836779382 1.0 13.660064264931021 -8.55208812608263 22.740781054544758 1.0000000032068956 0.6850041777547844 0.45277279292112715 0.10323320903077107 2836.3383202259756 2208210.297698133 0.09954952369449263 0.025703576489230644 2.8048644232720114e-09 8.55208812608263 -0.31499582545211124 AAEEEDEADPKR ddPTM_PC-9_AZD4547_30min_R2 4 AAEEEDEADPKR 12 1 P20962 P20962 PTMS Parathymosin 0 ;;; 123.01 0.00023705 44035400.0 112590.0 114573.0 128871.0 167873.0 157174.0 146076.0 131155.0 137841.0 130227.0 129436.0 False True 148391.2779825171 151606.4816528702 127162.08633718452 129172.47346199541 135353.10312072403 136941.84462787124 142827.54091909816 116540.8407210691 137110.5333563102 124904.48503725206 1.1880380271233673 1.2137793259197571 1.0180746215739103 1.034170017381445 1.0836528654704092 1.0963725168638188 1.1434940937188978 0.9330396797705979 1.0977230586669304 1.0 16.93046575622519 -5.255957622932376 24.99614849045741 1.0539396324349708 1.2009086932716344 0.5279746149911504 0.056705507686923166 342.13390807082567 1560075.6943653761 0.01449698994156007 0.036184882150941414 5.546798342029517e-06 5.255957622932376 0.1469690608366636 AAEEEDEADPKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AAEEEDEADPKR 12 1 P20962 P20962 PTMS Parathymosin 0 ;;; 120.86 0.00029968 50607000.0 160833.0 179266.0 157187.0 227198.0 222523.0 188683.0 204461.0 177909.0 176409.0 150195.0 False True 188058.8503034533 197062.34375227895 160934.9342150169 214468.8326458542 178921.21554472105 178788.13132256214 185092.9739105491 173239.07726016743 178988.64789196022 177424.1645570342 1.0599393311106757 1.1106849185074332 0.9070632211616432 1.2087915599394679 1.008437695008594 1.0076876042726945 1.0432230264274385 0.97641196560054 1.0088177579352395 1.0 17.436842987528117 -6.441987410027026 24.999999999309 1.0079962483446445 1.0684008335086275 0.16478736163816243 0.07064144757572816 196.3569870036162 60683.60156501446 0.021082475938942236 0.023905273462937943 3.6142033987694097e-07 6.441987410027026 0.06040458516398295 AAEEEDEADPKR ddPTM_PC-9_Lapatinib_30min_R1 4 AAEEEDEADPKR 12 1 P20962 P20962 PTMS Parathymosin 0 ;;; 107.09 0.001008 70509000.0 169443.0 153700.0 163750.0 149961.0 167718.0 168808.0 158661.0 143735.0 167053.0 131592.4 False True 167026.7117479596 153344.11709329975 150287.10709327928 160989.63219523113 157853.15698627505 161588.47535066796 166875.69024576488 150413.45283041522 148237.73199392363 154337.9710041486 1.0822139921968388 0.9935605353343531 0.9737532903632611 1.0430980214901473 1.0227758986285491 1.0469780981267693 1.0812354805498854 0.9745719206479144 0.9604748010451621 1.0 17.23573351910718 -7.809552897217549 24.962793853198 0.9756422865563926 1.0311927808483299 0.37196012731173766 0.03333042253117192 135.94946837338836 70532.87720964735 0.018959725758067147 0.009107984005480472 1.5504119345854586e-08 7.809552897217549 0.05555049429193726 AAEEPSKVEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAEEPSKVEEK 11 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 0 78.098 0.024329 2813700.0 11089.0 13680.0 15408.0 16858.0 17339.0 17240.0 15061.0 15009.0 12647.0 11638.0 False True 12966.148682266627 15038.05999202963 15775.385155165393 15913.500914373417 13941.54741905296 16335.904050714527 13634.313047802654 14615.029653350022 12831.938449226656 13747.877273642685 0.9431382332111167 1.0938459583764595 1.147477886306843 1.1575242197486477 1.0140872762794864 1.1882491911703041 0.9917395083197494 1.0630753651961844 0.9333759818927058 1.0 13.74692125759012 -7.32004763087094 24.999822233976584 1.0023038965027427 1.0929958564961015 0.2812668285830313 0.07311029508591899 374.4289081631162 159714.13425604842 0.03025452397102398 0.020397600030053236 4.785776018605226e-08 7.32004763087094 0.09069195999335888 AAEEQGDDQDSEK ddPTM_PC-9_AZD4547_30min_R2 2 AAEEQGDDQDSEK 13 0 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 0 ; 158.11 5.7791e-12 4033600.0 29467.9 32704.0 38760.8 45983.0 37543.0 38009.0 37018.0 39523.0 35037.0 31848.5 False True 38838.07922960317 43274.92843842323 38246.806466143214 35382.329780268046 32330.80248935163 35632.29122142411 40312.53028663177 33415.62849818851 36888.98429054681 30733.493708928927 1.2637053111316023 1.4080705841083947 1.2444666014339745 1.1512628572386647 1.0519728995196742 1.1593960504097178 1.3116806917047596 1.0872707416430287 1.2002860670483924 1.0 14.907524157871391 -1.5228787452803376 0.1919266897218532 1.066057785419761 2.3095939601593796 0.39586949984077036 0.09162418452181331 60.93970771853258 0.7170159583679894 0.194297057470113 22.50885648886597 0.029999999999999995 1.5228787452803376 1.2435361747396185 AAEEQGDDQDSEK ddPTM_PC-9_Lapatinib_30min_R1 2 AAEEQGDDQDSEK 13 0 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 0 ; 206.69 3.2536e-09 8384800.0 16163.099999999999 29244.0 26601.0 26938.0 29707.0 27330.0 30773.0 32251.0 28386.0 28964.0 False True 15932.611230050466 29176.287314746016 24413.96846282945 28919.110382533698 27959.692666209154 26161.159609341674 32366.275366554597 33749.499198063946 25188.869762168386 33970.38880789595 0.4690146857061333 0.8588741059085079 0.7186838102116382 0.8513034851049996 0.823060719861714 0.7701165788029153 0.9527790673691524 0.9934975837020547 0.7414948914659929 1.0 15.051990110219117 -4.477148646302937 2.0108908895889708 0.8566458868597177 2.8669970738546625e-35 0.5867246166733011 0.09636423726076544 1.7259873219157393 3.4639098177806504 0.02558382973234218 3.6725927654130084 3.333123101792135e-05 4.477148646302937 -0.8566458868597177 AAEPHFGT(ph)LPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAEPHFGTLPK 11 0 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;A8MY87 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 AAEPHFGT(1)LPK 92.039 0.016493 3102100.0 51888.0 51179.0 41740.0 63208.0 56504.0 48633.0 46155.0 42786.0 42466.0 38608.0 True False 60671.61356528549 56259.7128897722 42735.23989983151 59666.66068310092 45432.44681735789 46082.599866496465 41782.86426673733 41662.91283551428 43086.98491222101 45607.32477924014 1.3303041530930229 1.2335674842165023 0.9370257980859258 1.3082692521851316 0.9961655729045996 1.0104210253409265 0.916143721846986 0.9135136304789072 0.9447382656356472 1.0 15.476977927054548 -2.910740658362209 0.33508465501525925 0.9245361000969933 2.6679408157553066 0.5711779495650339 0.10260643483034547 17.101886022544402 0.5653877487659406 0.09436114354943292 15.565230062973312 0.001228172422985355 2.910740658362209 1.7434047156583135 AAEPHFGT(ph)LPK ddPTM_PC-9_Lapatinib_30min_R1 3 AAEPHFGTLPK 11 0 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;A8MY87 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 AAEPHFGT(1)LPK;AAEPHFGT(1)LPK;AAEPHFGT(1)LPK 99.161 0.009807399999999999 9890900.0 193459.0 151904.0 163848.0 147171.0 133792.0 125420.0 93591.0 108504.0 116244.0 86348.0 True False 190700.23918396435 151552.27562095367 150377.0499115706 157994.4462880637 125922.61760519253 120056.07896829989 98436.68403571987 113545.49195332642 103151.37661641314 101273.13674852221 1.8830288594447735 1.4964706385789432 1.4848661228394795 1.560082479526528 1.2433960440850076 1.1854681589098874 0.9719920523460657 1.1211807553199273 1.018546279183145 1.0 16.627892016598707 -5.792530793496329 0.47459585097782686 0.9740021817084389 1.936779398535481 0.8846520464054525 0.09638066744377384 0.6535474271995864 0.22235352320990048 0.07887636517225373 0.3216322069442959 1.6123866975771576e-06 5.792530793496329 0.9627772168270422 AAEQGQQDPNKNLS(ph)PTAVINITSEK ddPTM_PC-9_Lapatinib_30min_R1 1 AAEQGQQDPNKNLSPTAVINITSEK 25 1 Q92870;Q92870-4;H0YAJ5;G5E9Y1;Q92870-2;D6RB55 Q92870 APBB2 Amyloid beta A4 precursor protein-binding family B member 2 1 AAEQGQQDPNKNLS(0.968)PT(0.027)AVINIT(0.003)S(0.001)EK 74.28 8.8397e-05 2892400.0 8601.7 11480.0 11842.0 9416.9 15073.0 14046.0 10967.0 12135.0 11522.0 11647.0 True False 8479.038180641415 11453.41876532909 10868.396471441923 10109.450239857513 14186.435774658174 13445.285322825213 11534.817598056881 12698.836400995515 10224.271027961111 13660.168431348016 0.6207125646550088 0.8384537001055734 0.7956268274482327 0.7400677590956973 1.0385256848006685 0.9842693661060812 0.8444125455720021 0.929625170056733 0.7484732768373454 1.0 13.73768765187236 -3.8954903980350473 0.6516035093874316 0.9075362800374287 1.1379600266540928e-13 0.4242417055076635 0.09608043370912903 9.739947797866177 1.3285322802709116 0.04260601122067262 8.558033354395464 0.00012720658743134376 3.8954903980350473 -0.9075362800373149 AAES(ph)AEIEPR ddPTM_PC-9_AZD4547_30min_R2 1 AAESAEIEPR 10 0 Q9NS91 Q9NS91 RAD18 E3 ubiquitin-protein ligase RAD18 1 AAES(1)AEIEPR 93.839 0.017161000000000003 0.0 21977.0 18310.0 19697.0 24384.0 25282.0 27320.0 19095.0 25182.0 22401.0 27239.0 True False 28965.228850002517 24228.349428434714 19435.804910208823 18762.64552904456 21772.03069908606 25611.676081173067 20794.418008083463 21290.700524792745 23585.0711274521 26285.37090090632 1.1019524494898336 0.9217427260118791 0.7394152809743566 0.7138056221378114 0.8282945970656004 0.9743699709517881 0.7911023240446826 0.8099828838275454 0.897269862250218 1.0 14.681972471816017 -4.853306862147539 3.4116951204326487 0.8346882481099863 1.1163015378155015 0.4346751191824181 0.0881414416144288 0.24292181335018914 4.702694076472529 0.0227334880107965 0.1598644755811212 1.4018228598709888e-05 4.853306862147539 0.28161328970551514 AAES(ph)AEIEPR ddPTM_PC-9_Lapatinib_30min_R1 1 AAESAEIEPR 10 0 Q9NS91 Q9NS91 RAD18 E3 ubiquitin-protein ligase RAD18 1 AAES(1)AEIEPR 95.477 0.005901600000000001 3756200.0 23307.0 18815.0 26258.0 16718.0 20409.0 25215.0 24865.0 16949.0 15546.0 14823.0 True False 22974.637906019667 18771.435023490154 24099.16859881117 17947.49748961313 19208.58274563781 24136.613229035866 26152.388034620606 17736.512415366527 13795.045773362554 17385.13579959403 1.3215104081359066 1.0797404886494182 1.3861938656454973 1.0323472704787404 1.1048854013603022 1.3883476958287257 1.504295872985433 1.0202113241922852 0.793496578478535 1.0 14.08556671590666 -7.98847648581882 24.26656246764826 0.9001167861511791 1.2488566737648898 0.5003130390308688 0.1504645663529513 121.80366106890737 256497.60070585358 0.08493951796775988 0.040744512010014854 1.0268890294295637e-08 7.98847648581882 0.3487398876137108 AAES(ph)PSPR ddPTM_PC-9_AZD4547_30min_R2 2 AAESPSPR 8 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 AAES(0.701)PS(0.299)PR;AAES(0.824)PS(0.176)PR 86.13600000000001 0.012702 5848500.0 42637.0 33733.0 34863.0 45823.0 39574.0 41687.0 39397.0 41829.0 54235.0 51285.0 True False 56194.67909530677 44636.53256523148 34400.69384092048 35259.21530829271 34079.833196963504 39080.305299994936 42903.25667789809 35365.28918479688 57101.75137705304 49489.52775993909 1.1354862662641 0.9019389472001382 0.695110569811645 0.7124581078915534 0.6886271649686367 0.78966817969174 0.866915863210712 0.7146014679377172 1.153814836424362 1.0 15.594835655303678 -8.263250913871323 24.995753284797864 1.0769074351874193 0.8056379496614858 0.38549266980024177 0.13296288509785983 172.24789792815338 2376591.6155448174 0.11365053594963603 0.03508696144432714 5.454426402607325e-09 8.263250913871323 -0.27126948552593344 AAES(ph)PSPR ddPTM_PC-9_Lapatinib_30min_R1 2 AAESPSPR 8 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 AAES(0.98)PS(0.02)PR;AAES(0.5)PS(0.5)PR 101.43 0.0045882 5465600.0 19821.4 38912.0 38626.0 36511.0 53366.0 43366.0 56315.0 52112.0 54215.0 45552.0 True False 19538.743201200432 38821.90165474614 35450.31938067181 39196.14073712556 50227.11680159283 41511.33727108348 59230.71514858877 54533.313764209175 48108.735790740444 53425.602505775336 0.36571872444654757 0.7266535113113507 0.6635455234564667 0.7336583753620456 0.9401319675555039 0.7769933388509017 1.1086578788172936 1.0207337157931742 0.90048092177416 1.0 15.70524365248026 -4.691077227923177 0.4249342290674904 1.0166684199139977 1.6676225846865055e-18 0.7770141219602955 0.09742492888969702 2.711600668064164 0.36230570602011175 0.07441752902628097 1.4275020588323055 2.0366798752160416e-05 4.691077227923177 -1.0166684199139977 down AAESETPGKS(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 2 AAESETPGKSPEK 13 1 O76021;J3QSV6;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 AAES(0.011)ET(0.058)PGKS(0.931)PEK;AAES(0.15)ET(0.159)PGKS(0.691)PEK 130.27 0.0010585999999999998 46666000.0 33797.0 37469.0 29592.0 19092.8 22680.9 27823.0 39242.0 29573.0 34163.0 35443.0 True False 44543.74297872934 49580.121503769566 29199.590744930687 14691.249940819473 19532.04853583185 26083.223411657305 42734.46197817288 25003.17236993469 35968.78643485321 34202.151358009585 1.3023666994648837 1.4496199664398803 0.853735498661625 0.42954169131173736 0.571076606596496 0.7626193784897406 1.2494670738940277 0.7310409251223712 1.0516527471722887 1.0 15.061799454833563 AAESETPGKS(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AAESETPGKSPEK 13 1 O76021;J3QSV6;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 AAES(0.005)ET(0.225)PGKS(0.77)PEK;AAES(0.18)ET(0.008)PGKS(0.812)PEK;AAES(0.007)ET(0.116)PGKS(0.877)PEK;AAES(0.002)ET(0.138)PGKS(0.86)PEK 127.03 0.00058956 60954400.0 67676.0 100730.0 60890.2 65768.0 65409.0 45187.9 72118.0 69110.0 53682.0 48205.7 True False 79132.21013807159 110729.80869862143 62342.05329536942 62083.23218273287 52592.57599243529 42818.16697524842 65286.46095089519 67295.93572809784 54466.9976936337 56945.01181388878 1.3896249665676845 1.9445040956443291 1.094776369510987 1.090231263550127 0.9235677422338872 0.7519212940931405 1.1464825253574178 1.1817705113142938 0.9564840880470113 1.0 15.79728185192098 -5.368573994421044 5.953899115504668 1.0134361129865692 1.6626001655456986 0.7015734971897832 0.16978323624064354 0.11265613484747439 5.250345991572806 0.044480694644726676 0.09432926043348527 4.279824943795509e-06 5.368573994421044 0.6491640525591293 AAESETPGKS(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 4 AAESETPGKSPEK 13 1 O76021;J3QSV6;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 AAESET(0.016)PGKS(0.984)PEK;AAES(0.02)ET(0.157)PGKS(0.824)PEK;AAES(0.024)ET(0.035)PGKS(0.94)PEK;AAES(0.167)ET(0.331)PGKS(0.501)PEK 153.79 0.00014411 76254700.0 35481.9 67207.0 48536.600000000006 56000.3 72267.0 57404.5 60773.0 67765.0 47410.6 60339.0 True False 34975.92159941647 67051.38632068573 44546.1081046941 60118.74887352447 68016.39714238851 54949.44335142533 63919.52857542719 70913.60928829506 42070.71897224901 70768.5157533362 0.49422997256753426 0.9474748142859667 0.6294622351549614 0.8495126432080119 0.9611109745392964 0.7764673706447612 0.9032198555388504 1.0020502554478403 0.5944835570508018 1.0 16.110820041143356 -4.751297957340629 24.990730968676747 0.8472865129919399 0.49422924719331507 0.3767899093616609 0.13775796452023117 447.13243100873905 1101759.3291507137 0.03253120828093479 0.4367547648315262 1.7729726763879826e-05 4.751297957340629 -0.35305726579862484 AAESETPGKS(ph)PEKKPK ddPTM_PC-9_Lapatinib_30min_R1 1 AAESETPGKSPEKKPK 16 3 O76021;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 AAESET(0.001)PGKS(0.998)PEKKPK 60.657 0.036814 180050000.0 137100.0 144180.0 76996.0 123680.0 108440.0 80690.0 81348.0 76259.0 93445.0 107460.0 True False 135144.92885893947 143846.16006839278 70665.68609315513 132775.8397843852 102061.77240124292 77239.07679757703 85559.801401179 79802.27153716653 82920.24008052656 126034.31781855054 1.072286748546577 1.1413253354970005 0.5606860680191194 1.0534895739709587 0.8097935083695182 0.6128416302357966 0.6788611457742643 0.6331789064947889 0.6579179505688715 1.0 16.943457092332473 -4.662758217812009 0.6650730343810966 0.7091650227096469 1.4606575728300495 0.32714378526976173 0.17306309292505895 3.9986057905142953 1.1995085399194885 0.07647152657487333 2.365894346581598 2.1739111106569843e-05 4.662758217812009 0.7514925501204026 AAESLTAIPEPAS(ph)PQLLETPIHASQIQK ddPTM_PC-9_AZD4547_30min_R2 1 AAESLTAIPEPASPQLLETPIHASQIQK 28 0 Q14676;Q14676-3;Q14676-2 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 AAESLT(0.006)AIPEPAS(0.994)PQLLETPIHASQIQK 105.71 1.7672e-10 6752500.0 11679.0 13011.0 34117.0 93862.0 49968.0 29717.0 19074.0 57830.0 23815.0 38900.0 True False 15392.679061709017 17216.551306027537 33664.58628834821 72223.56605344411 43030.805710463246 27858.79129224816 20771.54904876585 48893.702301197845 25073.812280713897 37538.12284023848 0.41005457644272625 0.4586417754372227 0.8968105952347174 1.9240057996726743 1.146322790129957 0.7421466281309439 0.5533454386403166 1.3025079199961194 0.6679559440792379 1.0 15.196068887022681 -5.312654890189806 4.46602588456106 1.054813360635623 0.4272824114782382 0.30142521690750335 0.36566231564829904 0.2533726454041027 10.957271654637758 0.10345459152742742 0.23786372796331035 4.867938802157301e-06 5.312654890189806 -0.6275309491573847 AAESLTAIPEPAS(ph)PQLLETPIHASQIQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAESLTAIPEPASPQLLETPIHASQIQK 28 0 Q14676;Q14676-3;Q14676-2 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 AAESLTAIPEPAS(1)PQLLETPIHASQIQK 107.98 1.2713999999999999e-10 3381100.0 5607.1 5724.4 12841.0 9041.8 11513.0 15071.0 9185.4 6890.6 10781.0 5680.8 True False 6556.2712847269595 6292.680600758362 13147.178139763682 8535.217259911109 9257.110296762025 14280.650229020794 8315.292415462878 6709.729051194193 10938.651729351826 6710.6840708119435 0.9769900081041513 0.937710751148056 1.9591412739793859 1.2718848287069504 1.3794585170572606 2.128046869488961 1.2391124850639539 0.9998576866966656 1.6300352712072064 1.0 12.712244123407206 -10.983416656622323 3.884570917175055 0.9968215704435559 1.3965272201979506 0.08451075629437743 0.38609050615007434 0.010922627981927991 0.0015168587780952831 0.38377587090349524 0.09241441162802783 1.038922958031145e-11 10.983416656622323 0.3997056497543947 AAESPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 AAESPSPR 8 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 AAES(0.028)PS(0.972)PR;AAES(0.006)PS(0.994)PR 99.01299999999999 0.0053299 30260000.0 38154.0 50686.0 65081.0 83348.0 69948.0 77680.0 82398.0 78272.0 88896.0 92415.0 True False 50286.17834749948 67069.25828124754 64217.98341683004 64133.4063137634 60236.92759036745 72822.65732011442 89731.26237392289 66176.86091162654 93594.86107521916 89179.5789789367 0.5638754849849265 0.752069689598878 0.7200974051693793 0.7191490142481055 0.6754565145973025 0.8165844485239652 1.0061862076643857 0.7420629438860307 1.0495100127948047 1.0 16.444425768184963 -7.181539209005161 0.5427056273728811 1.006821264580575 0.6512936086535885 0.6477683338895059 0.09091884506749463 0.5900263486916756 0.3670754478298572 0.0831236741806515 0.07254132437035467 6.58355989518167e-08 7.181539209005161 -0.35552765592698643 AAESPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AAESPSPR 8 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 AAES(0.16)PS(0.84)PR;AAES(0.032)PS(0.968)PR 89.029 0.010532 32010000.0 44154.0 70208.0 107114.0 64023.0 122112.0 92678.0 85431.0 81366.0 90519.0 79973.0 True False 51628.40011874842 77177.7862514924 109668.00399210727 60435.99887536654 98185.03018832656 87817.80252970534 77338.35721312196 79230.228714403 91842.66912987636 94471.4718340802 0.5464972559062394 0.8169427738676431 1.1608584249085974 0.6397275039972913 1.0393087805466656 0.9295695390873059 0.8186424505902792 0.8386683003473755 0.9721735815779308 1.0 16.527591114627462 -4.821889386989147 3.9655097470300262 0.9135124588975513 0.5278244293452437 0.41800733320656325 0.13385885531122757 0.20515550343828923 5.6493059811699 0.03186369149449659 0.20635869065101026 1.5069908416549724e-05 4.821889386989147 -0.38568802955230763 AAESPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 AAESPSPR 8 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 AAES(0.009)PS(0.991)PR;AAESPS(1)PR 106.88 0.003819 28103000.0 49117.0 92829.0 85639.0 98772.0 100708.0 66507.0 85782.0 90088.0 92562.0 68454.0 True False 48416.58257304534 92614.06015389692 78598.09199609967 106036.02237373304 94784.55343954591 63662.650645389265 90223.37222545037 94273.81736241313 82136.69283892866 80286.18269077863 0.6030500012626243 1.153549179322661 0.9789740819889192 1.3207256693487301 1.180583635475703 0.7929465383923567 1.123772101271083 1.174222191202037 1.0230489243121355 1.0 16.2928640998109 -4.756710652225433 24.999147783963913 1.0879591131517432 0.6030492683403211 0.5260730013473751 0.13661839718746788 117.76720597760583 622520.4103570413 0.034385276193811244 0.2715099207045531 1.7510129087106825e-05 4.756710652225433 -0.4849098448114221 AAET(ph)GLMS(ph)SFK ddPTM_PC-9_Lapatinib_30min_R1 1 AAETGLMSSFK 11 0 A0A1B0GUS7 A0A1B0GUS7 2 AAET(1)GLMS(0.5)S(0.5)FK 59.067 0.027821 275660.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AAEVLNK ddPTM_PC-9_Lapatinib_30min_R1 1 AAEVLNK 7 0 A0A087X0X3;P52272-2;P52272;M0R2T0;M0R019;M0QYQ7;M0R0N3 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 111.04 0.004536 0.0 36665.0 37733.0 37852.0 33805.0 43166.0 37924.0 37479.0 29202.0 36983.0 32728.0 False True 36142.150376462465 37645.631556808614 34739.954672945416 36291.13247017416 40627.06074762123 36302.07892516185 39419.479233844584 30558.83152714223 32817.58509174497 38384.99119268122 0.9415698493986787 0.9807383143020343 0.9050400584582967 0.9454511084294246 1.0584100578188358 0.945736283823441 1.0269503263911288 0.7961140690054089 0.8549587761271188 1.0 15.22825469662604 -7.755542605897542 24.999928781896973 0.8691523153927205 0.9710409133423232 0.2821124497235832 0.06326948376645361 151.35460502552343 641689.7831428836 0.02981430194186479 0.016627371688466935 1.7557286422660082e-08 7.755542605897542 0.1018885979496027 AAFDDAIAELDTLSEESYK ddPTM_PC-9_Lapatinib_30min_R1 1 AAFDDAIAELDTLSEESYK 19 0 P62258;P62258-2;K7EM20 P62258 YWHAE 14-3-3 protein epsilon 0 218.6 1.9911e-86 0.0 1224.4 3140.3 2101.4 2140.0 1952.2 1183.7 1235.7 2308.6 2257.4 2226.1 False True 1206.939831472539 3133.0288282894558 1928.6310036385776 2297.3827388307277 1837.375434172872 1133.0759103394716 1299.6784996734639 2415.8659839586494 2003.1478405241635 2610.8784189082016 0.4622734719210895 1.1999903195797235 0.7386904689514722 0.8799271242172321 0.7037384126608287 0.43398264052957825 0.49779357409409897 0.9253077303265997 0.7672313754701092 1.0 11.350319561722195 -6.295122871845643 9.273221072211015 0.6919243567426724 0.8414988645061662 0.029389902940155643 0.23319079755241048 1.2104969104742924 323.3685140508063 0.07183034897008088 0.08203473598070232 5.068472892925346e-07 6.295122871845643 0.1495745077634938 AAFTTPDHAPLS(ph)PQSSVASSGSEQTEEQGSSR ddPTM_PC-9_AZD4547_30min_R2 4 AAFTTPDHAPLSPQSSVASSGSEQTEEQGSSR 32 0 M0QZ22;Q5PRF9;A0A087WZT0;M0R0X3 M0QZ22 SAMD4B Protein Smaug homolog 2 1 AAFTTPDHAPLS(0.999)PQS(0.001)SVASSGSEQTEEQGSSR;AAFTTPDHAPLS(0.967)PQS(0.032)S(0.001)VASSGSEQTEEQGSSR;AAFTTPDHAPLS(1)PQSSVASSGSEQTEEQGSSR;AAFTTPDHAPLS(0.999)PQS(0.001)SVASSGSEQTEEQGSSR 135.03 7.170300000000001e-18 210294000.0 169550.0 152608.0 271412.0 423048.0 335170.0 286003.0 230477.0 334366.0 215494.0 250572.0 True False 223463.37314091713 201935.55158790667 267812.89954254986 325520.8196264452 288637.43095533154 268119.1871977943 250989.00650688898 282697.4176663039 226884.57290027972 241799.55054818132 0.924167859842194 0.8351361742819646 1.107582288450884 1.3462424511892608 1.19370540723076 1.1088489891314688 1.0380044377165893 1.169139549785777 0.938316768521331 1.0 17.88345203737574 -5.290262106872674 8.395424431030785 1.1274310196895392 0.8796544249208945 0.4178977672441957 0.10894643373312768 0.23951386212985926 65.50777412055795 0.029470439859299945 0.06297577979112617 5.125519535402084e-06 5.290262106872674 -0.24777659476864466 AAFTTPDHAPLS(ph)PQSSVASSGSEQTEEQGSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AAFTTPDHAPLSPQSSVASSGSEQTEEQGSSR 32 0 M0QZ22;Q5PRF9;A0A087WZT0;M0R0X3 M0QZ22 SAMD4B Protein Smaug homolog 2 1 AAFTTPDHAPLS(0.871)PQS(0.092)S(0.036)VAS(0.001)SGSEQTEEQGSSR;AAFTTPDHAPLS(0.997)PQS(0.003)SVASSGSEQTEEQGSSR;AAFTTPDHAPLS(0.933)PQS(0.058)S(0.008)VAS(0.001)SGSEQTEEQGSSR;AAFTTPDHAPLS(0.999)PQS(0.001)SVASSGSEQTEEQGSSR 105.53 8.9568e-16 155992000.0 133227.0 151674.0 191577.0 207543.0 236142.0 217733.0 237776.0 208704.0 203964.0 168103.0 True False 155779.6997468066 166731.19234145497 196144.92223981887 195915.03857348496 189871.67025953115 206314.69818295952 215252.13593083582 203225.74114016633 206946.58763802174 198578.74319738435 0.7844731880086676 0.8396225580686983 0.9877437991681401 0.9865861542831313 0.9561530464053823 1.038956611674623 1.0839636330907703 1.0234012858977708 1.0421386715713066 1.0 17.599351672705744 -4.5256808367672665 0.6697128795528581 1.0370211200669888 0.5114255304122892 0.8666905847567614 0.032393252344986787 1.4765789249888903 0.394558996159885 0.014919614979563841 0.6390313417375381 2.9807061471619445e-05 4.5256808367672665 -0.5255955896546995 AAFTTPDHAPLS(ph)PQSSVASSGSEQTEEQGSSR ddPTM_PC-9_Lapatinib_30min_R1 4 AAFTTPDHAPLSPQSSVASSGSEQTEEQGSSR 32 0 M0QZ22;Q5PRF9;A0A087WZT0;M0R0X3 M0QZ22 SAMD4B Protein Smaug homolog 2 1 AAFTTPDHAPLS(1)PQSSVASSGSEQTEEQGSSR;AAFTTPDHAPLS(0.994)PQS(0.006)S(0.001)VASSGSEQTEEQGSSR;AAFTTPDHAPLS(0.928)PQS(0.066)S(0.005)VAS(0.001)SGSEQTEEQGSSR;AAFTTPDHAPLS(0.986)PQS(0.012)S(0.001)VASSGSEQTEEQGSSR 170.06 2.6325e-19 199337000.0 186200.0 153132.0 209585.0 149755.0 203419.0 200848.0 162889.0 176213.0 210864.0 154358.0 True False 183544.7538551019 152777.43226240214 192353.73032149603 160768.48226803538 191454.2943571415 192258.19923955578 171322.59539800163 184400.49927718387 187114.27582364078 181038.57463089377 1.0138433437697894 0.8438943610437102 1.0625013520663864 0.8880344014849565 1.0575331514152915 1.0619736684932306 0.9463319944232806 1.0185702116421569 1.0335602575591103 1.0 17.465937605443273 -6.275539996450826 24.981669937682227 1.0190391844614197 0.9522297160034727 0.21097885558461493 0.0640302489874081 1227.2555453180191 2174289.2284358223 0.018935794695097125 0.021575068118472283 5.302247592086693e-07 6.275539996450826 -0.066809468457947 AAFVLPEFAR ddPTM_PC-9_Lapatinib_30min_R1 1 AAFVLPEFAR 10 0 K7EL89;P19623 K7EL89 SRM Spermidine synthase 0 98.58200000000001 0.021672 1245600.0 8531.9 7721.6 8931.5 7872.4 7641.8 9193.2 8037.4 6453.5 7977.3 8408.1 False True 8410.233541441165 7703.72110961369 8197.18654658702 8451.362557556553 7192.324348356858 8800.0282663959 8453.537244699768 6753.353169660035 7078.812469306903 9861.428881910984 0.8528412709914913 0.7811972485797448 0.8312372014996003 0.8570119663955652 0.7293389664402369 0.8923684763916888 0.8572324909432 0.6848250137510848 0.7178282735772409 1.0 13.267580987197574 AAGALGSASS(ph)GSMPNLAAR ddPTM_PC-9_Lapatinib_30min_R1 1 AAGALGSASSGSMPNLAAR 19 0 Q9P2Q2 Q9P2Q2 FRMD4A FERM domain-containing protein 4A 1 AAGALGS(0.005)AS(0.106)S(0.525)GS(0.363)MPNLAAR 80.834 0.02076 0.0 29110.0 26518.0 24187.0 20468.0 24432.0 21794.0 24659.0 23689.0 27449.0 19304.0 True False 28694.88606187981 26456.599200261055 22198.43822452 21973.2849992464 22994.957795160135 20861.921424295375 25935.722362586344 24789.677420946235 24357.404569215792 22640.670679036837 1.2674044187413853 1.1685430867009348 0.9804673430047148 0.9705227071560042 1.0156482606520723 0.9214356641657078 1.145536840770376 1.0949179806717995 1.0758252224289668 1.0 14.466629074953744 -5.049934748548234 3.5643084464996924 1.027654834200344 1.25607839576152 0.6185329909421948 0.06253663427702594 0.16032193593221794 4.0131494181103875 0.017725422873198674 0.06696665858952718 8.913848559915172e-06 5.049934748548234 0.22842356156117605 AAGALGSASSGS(ph)MPNLAAR ddPTM_PC-9_AZD4547_30min_R2 2 AAGALGSASSGSMPNLAAR 19 0 Q9P2Q2 Q9P2Q2 FRMD4A FERM domain-containing protein 4A 1 AAGALGSAS(0.19)S(0.19)GS(0.619)MPNLAAR;AAGALGSAS(0.2)S(0.123)GS(0.677)MPNLAAR 191.15 1.6343e-11 31653000.0 27792.6 27900.0 45346.0 57784.0 45206.0 44765.0 42986.0 45104.0 37089.0 42221.0 True False 36630.06867800788 36918.12938576346 44744.68241144997 44462.79155390053 38929.92721235998 41965.83747341549 46811.6707250838 38134.21318681007 39049.44882130582 40742.85564107224 0.8990550147172719 0.9061252287025966 1.0982215582931196 1.091302778224467 0.9555031575429221 1.0300170867530059 1.1489540924051893 0.9359730089308606 0.9584367174779148 1.0 15.314259480983155 -5.234826223794186 21.295020116507963 1.0291776633892056 0.9025896681341672 0.36647374830794344 0.06555100506753381 130.3062100039854 104263.01850392512 0.017378933451500985 0.04590995525949419 5.823361839572551e-06 5.234826223794186 -0.1265879952550384 AAGALGSASSGS(ph)MPNLAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AAGALGSASSGSMPNLAAR 19 0 Q9P2Q2 Q9P2Q2 FRMD4A FERM domain-containing protein 4A 1 AAGALGSAS(0.144)S(0.144)GS(0.712)MPNLAAR;AAGALGS(0.008)AS(0.149)S(0.149)GS(0.694)MPNLAAR 154.47 1.781e-05 24062000.0 56399.0 57463.0 70477.0 65676.0 76719.0 72877.0 75542.0 63504.0 58106.0 66800.0 True False 65946.2367689744 63167.54688026302 72157.43896551106 61996.38664446491 61686.46268194961 69055.20182737362 68386.11488328192 61837.08728804982 58955.690324248 78910.31121149106 0.835711274692973 0.8004980073005269 0.91442344932741 0.7856563444326764 0.7817287973509692 0.8751099921820822 0.8666309108830812 0.7836376050059854 0.7471227703846993 1.0 16.267926209087577 -6.786409360415058 24.999862632511405 0.8417357389248553 0.8252572369469465 0.029509530152438845 0.07158496672654928 1712.8060646046144 1714843.2810720894 0.025071638088353873 0.022120867779529124 1.6352744060466338e-07 6.786409360415058 -0.016478501977908788 AAGALGSASSGS(ph)MPNLAAR ddPTM_PC-9_Lapatinib_30min_R1 3 AAGALGSASSGSMPNLAAR 19 0 Q9P2Q2 Q9P2Q2 FRMD4A FERM domain-containing protein 4A 1 AAGALGS(0.002)AS(0.157)S(0.157)GS(0.684)MPNLAAR;AAGALGS(0.008)AS(0.145)S(0.145)GS(0.701)MPNLAAR;AAGALGSAS(0.044)S(0.044)GS(0.912)MPNLAAR 139.12 0.00013196 33710800.0 191229.0 114115.0 106800.0 94377.0 92536.0 95211.0 84494.0 80207.0 99191.0 71699.0 True False 188502.03939289646 113850.7737287046 98019.31625992214 101317.79941244281 87093.21441277585 91139.04747768129 88868.68588768276 83933.71003004917 88019.065052464 84092.07661708773 2.241614751069096 1.3538822955594585 1.1656189287161016 1.2048435891741882 1.0356887107135404 1.0838006521432675 1.0568021324095165 0.998116747814902 1.0466986735653794 1.0 16.359682251804557 -2.288684590305243 0.9936470093412892 1.0522065031586876 199.99999999999886 0.9765018115276127 0.05466311852882605 38.49149090384551 0.3062451480431097 0.01813353464965941 17121.868915964387 0.005144171153216834 2.288684590305243 198.94779349684018 up AAGARPLT(ph)SPESLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAGARPLTSPESLSR 15 1 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 AAGARPLT(0.596)S(0.388)PES(0.016)LSR 61.957 0.03242 36123000.0 20839.0 25767.0 29271.0 34714.0 29399.0 32858.0 23446.0 32780.0 32330.0 25324.0 True False 24366.631110988757 28324.977471829476 29968.931650885683 32769.08712430648 23638.47699248735 31134.868636796866 21225.0251456597 31919.559733280952 32802.76508764906 29915.0407353263 0.814527759683593 0.9468473642551608 1.001801465558285 1.0954050644366957 0.7901870233649044 1.0407764078365465 0.7095101535528023 1.0670070622898247 1.0965308514159127 1.0 14.868583407062232 AAGARPLTS(ph)PESLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAGARPLTSPESLSR 15 1 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 AAGARPLT(0.217)S(0.781)PES(0.002)LSR 129.29 7.5061e-05 14720000.0 18556.0 15330.0 23210.0 23778.0 35063.0 26354.0 23813.0 19762.0 22897.0 20754.0 True False 21697.164302294135 16851.861087559504 23763.414424415183 22445.795749316127 28192.656851851556 24971.949846434476 21557.260248809813 19243.268439569787 23231.825308131785 24516.53591142638 0.8850012245074874 0.687367136549882 0.9692810807476193 0.9155370004314048 1.1499445498216512 1.0185757864264926 0.8792947065071561 0.7849097649477106 0.9475982003356423 1.0 14.581467525932881 -5.280817053742946 24.689957967992125 0.9551316201228528 0.7861841786084414 0.3206764992341514 0.10003571743826628 772.0847116266607 983746.897850787 0.02831437774127198 0.05909344561566323 5.23821049379104e-06 5.280817053742946 -0.16894744151441143 AAGDGDCGTTHSR ddPTM_PC-9_AZD4547_30min_R2 2 AAGDGDCGTTHSR 13 0 H0YCY6;Q3LXA3-2;Q3LXA3;I3L252 H0YCY6 TKFC;DAK Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing);ATP-dependent dihydroxyacetone kinase;FAD-AMP lyase (cyclizing) 0 ; 180.61 7.9089e-05 1021150.0 12752.2 8476.0 7517.700000000001 8628.7 10083.2 7830.4 7984.1 8791.9 13901.400000000001 15672.900000000001 False True 16807.134337762287 11215.70124278606 7418.01038602208 6639.486527086072 8683.321728701234 7340.763850147052 8694.669432748842 7433.313872763292 14636.199623729422 15124.196541459478 1.1112745256707968 0.7415733597510993 0.490473022199052 0.43899763593295416 0.5741344146710816 0.4853655418999647 0.5748847159526407 0.4914848767262833 0.9677340269684855 1.0 13.884570882172008 -8.27424328813846 23.11792777394943 0.9838674061188597 0.6009997718857184 0.3868083201765563 0.1859815061096855 337.62250197034933 609573.2780103405 0.1826865810510484 0.04869994934607527 5.318102601439891e-09 8.27424328813846 -0.3828676342331413 AAGDGDCGTTHSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAGDGDCGTTHSR 13 0 H0YCY6;Q3LXA3-2;Q3LXA3;I3L252 H0YCY6 TKFC;DAK Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing);ATP-dependent dihydroxyacetone kinase;FAD-AMP lyase (cyclizing) 0 166.62 0.00024794 527220.0 2331.5 4197.2 3593.9 2038.0 6672.9 5831.4 1987.3 4359.0 6209.0 7183.8 False True 2726.1769007759617 4613.870277671545 3679.5922059416516 1923.817467285148 5365.3931468134515 5525.591118407001 1799.0485571939575 4244.58086874227 6299.794878726044 8486.16607307049 0.321249534513242 0.5436931398635876 0.43359889192108286 0.2267004264022218 0.6322517259990563 0.65112926978198 0.21199780227056297 0.5001765028157742 0.7423605459145385 1.0 13.05089719690502 -8.457523812750079 2.3902544087005335 0.9943490994598335 0.4397321865526472 0.6166760235428541 0.1436134353305837 0.18440593095006652 2.286956721103548 0.13931029621401195 0.0382540205866098 3.4871946301480905e-09 8.457523812750079 -0.5546169129071863 AAGDGDCGTTHSR ddPTM_PC-9_Lapatinib_30min_R1 2 AAGDGDCGTTHSR 13 0 H0YCY6;Q3LXA3-2;Q3LXA3;I3L252 H0YCY6 TKFC;DAK Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing);ATP-dependent dihydroxyacetone kinase;FAD-AMP lyase (cyclizing) 0 ; 170.0 6.9848e-19 832750.0 5862.1 13542.099999999999 9559.6 8927.599999999999 12788.8 8655.0 16075.0 21386.5 15610.9 11265.1 False True 5778.505379022522 13510.744099474145 8773.646589123131 9584.16548560056 12036.587927748202 8284.845825790426 16907.284844420927 22380.19486525674 13852.636051935258 13212.25752519778 0.4373594268808366 1.022591640656951 0.6640535557523349 0.7253995365532425 0.9110167512851307 0.6270575493998636 1.2796666135349064 1.6938963551515942 1.0484685168689893 1.0 13.689589374684019 -7.27257829300509 22.136921118381686 1.313332894656117 0.7493407793374786 0.5462346291219815 0.23135047547292184 109.40444719681103 217421.98281592657 0.09072017993617404 0.06199634199470654 5.3385302384736217e-08 7.27257829300509 -0.5639921153186384 AAGGAPS(ph)PPPPVR ddPTM_PC-9_AZD4547_30min_R2 3 AAGGAPSPPPPVR 13 0 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 AAGGAPS(1)PPPPVR;AAGGAPS(1)PPPPVR;AAGGAPS(1)PPPPVR 161.87 1.8314e-12 255580000.0 111494.0 143736.0 218983.0 256939.0 222662.0 186071.0 181325.0 214245.0 193222.0 213435.0 True False 146946.77278073315 190195.85108932242 216079.14233904972 197705.68321797808 191749.22472588829 174435.95095534265 197462.57372692975 181138.35811032556 203435.32044946874 205962.7056145582 0.7134630142979944 0.9234480122108023 1.0491178084610309 0.9599101091047404 0.9309900263435593 0.8469297897153517 0.9587297522516736 0.8794716381775965 0.9877289184100192 1.0 17.65202360167097 -4.769033448629839 4.969492609144152 0.9459376573482486 0.6998255813241065 0.6242333933773934 0.054922548560813134 0.11420788050243505 7.327498958855724 0.014134225124888138 0.09734405028044134 1.7020274160606245e-05 4.769033448629839 -0.2461120760241421 AAGGAPS(ph)PPPPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 AAGGAPSPPPPVR 13 0 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 AAGGAPS(1)PPPPVR;AAGGAPS(1)PPPPVR;AAGGAPS(1)PPPPVR;AAGGAPS(1)PPPPVR;AAGGAPS(1)PPPPVR;AAGGAPS(1)PPPPVR 157.33 4.3108e-12 250227800.0 257275.0 353999.0 357602.0 357012.0 451704.0 393776.0 362111.0 358224.0 337970.0 266154.0 True False 300826.5760871261 389141.6812221122 366128.5878931367 337009.77508852084 363195.84378429473 373125.6933569704 327809.22462339 348820.99956970266 342912.17187357805 314405.6133260959 0.9568104491032547 1.2377058955957678 1.1645103407024564 1.0718949051936306 1.1551824407396774 1.186765367862472 1.0426315903062204 1.1094617423637145 1.0906680966853974 1.0 18.26226744981141 -8.84186806715852 0.642245426428448 0.998942032620388 1.1294461125797353 0.17742273779452034 0.0750283183746353 2.062093795027268 1.6790185268509572 0.08057234021480744 0.029674419997698574 1.4392357323729009e-09 8.84186806715852 0.1305040799593472 AAGGAPS(ph)PPPPVR ddPTM_PC-9_Lapatinib_30min_R1 1 AAGGAPSPPPPVR 13 0 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 AAGGAPS(1)PPPPVR 139.48 6.8597e-05 98875000.0 52933.0 47087.0 57827.0 43586.0 46652.0 44556.0 40250.0 39432.0 47399.0 37923.0 True False 52178.16571327666 46977.97294451665 53072.68727867524 46791.459838633695 43908.021081360945 42650.44374510894 42333.94805523747 41264.15467359329 42060.42548640242 44477.94002077882 1.1731246026434794 1.0562083793127535 1.1932361807646938 1.052014994776603 0.9871864807778502 0.9589122995620722 0.9517965093585778 0.9277442852415346 0.945646886226138 1.0 15.440802351274822 -6.148543890669352 2.2897679458780678 0.9539991623035133 1.1326808357263929 0.8046546283404118 0.039403893939987666 0.12229819507107861 1.2575261933239263 0.012111128904928714 0.016783573798476177 7.103233796732936e-07 6.148543890669352 0.17868167342287955 AAGGAPS(ph)PPPPVRR ddPTM_PC-9_AZD4547_30min_R2 3 AAGGAPSPPPPVRR 14 1 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 AAGGAPS(1)PPPPVRR;AAGGAPS(1)PPPPVRR;AAGGAPS(1)PPPPVRR 106.54 0.0012720000000000001 47487000.0 95652.0 105919.0 183885.0 249390.0 207876.0 191834.0 166916.0 184132.0 126223.0 196197.0 True False 126067.34631480346 140155.24539106386 181446.56475167553 191896.98853709092 179016.00560095024 179838.58965431008 181771.20064086167 155678.63033242527 132894.89009063825 189328.20274771928 0.6658667038781793 0.740276637907039 0.9583705022196505 1.0135678982427914 0.9455326940354994 0.9498774458549414 0.9600851748594088 0.8222685689351193 0.7019286517377515 1.0 17.530529808529877 -5.132145432476853 4.042643542462716 0.9191918857356891 0.681205308582326 0.49618405367465723 0.08814476489232499 0.19872653065390236 5.399768331924713 0.024585726493147816 0.07592759865121883 7.376571690265951e-06 5.132145432476853 -0.23798657715336313 AAGGAPS(ph)PPPPVRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AAGGAPSPPPPVRR 14 1 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 AAGGAPS(1)PPPPVRR;AAGGAPS(1)PPPPVRR;AAGGAPS(1)PPPPVRR 76.01 0.021503 80219400.0 65592.0 63063.0 99644.0 128474.0 145479.0 150895.0 116636.0 128075.0 131279.0 115465.0 True False 76695.43009894779 69323.47787115246 102019.89086197449 121276.01829832778 116973.4342797398 142981.80056453394 105587.39370848598 124713.16695667966 133198.70701953216 136397.8904795632 0.5622919081027814 0.5082445016372107 0.7479579816321306 0.8891341198308256 0.857589760871457 1.048269882047459 0.7741130990900945 0.9143335466420993 0.9765452130617049 1.0 17.057461806348698 -5.506876012364277 2.0632599482421776 0.9198061719897244 0.5249126518658165 0.8135652254493416 0.07408404312947987 0.13221240066904769 1.098222330136286 0.021096913647218645 0.055028040211782876 3.1126048343042792e-06 5.506876012364277 -0.3948935201239079 AAGGAPS(ph)PPPPVRR ddPTM_PC-9_Lapatinib_30min_R1 4 AAGGAPSPPPPVRR 14 1 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 AAGGAPS(1)PPPPVRR;AAGGAPS(1)PPPPVRR;AAGGAPS(1)PPPPVRR;AAGGAPS(1)PPPPVRR 119.17 0.00015433 36693300.0 195976.0 169551.0 154271.0 127932.0 137742.0 153685.0 124601.0 116334.4 174747.0 95537.5 True False 193181.34630240322 169158.41507668278 141587.43388328142 137340.5460486415 129640.28637119151 147112.25080723286 131052.23010262472 121739.72092360683 155065.15269251162 112051.02957928313 1.7240479362638548 1.509655160794329 1.263597794816329 1.2256964221061837 1.1569754143085573 1.3129040523732245 1.1695763135304085 1.0864667766168836 1.3838797668770486 1.0 16.773796379528775 -4.979896450226882 1.4351544673551042 1.193628740496195 1.836521142905394 0.7498909663505998 0.10102791731676154 0.3886271768580486 0.9628859380077941 0.02801416399144713 0.32474292103278735 1.0473782469435018e-05 4.979896450226882 0.6428924024091991 AAGGGAGS(ph)SEDDAQSRR ddPTM_PC-9_AZD4547_30min_R2 2 AAGGGAGSSEDDAQSRR 17 1 D6REM1;Q9H4A6 D6REM1 GOLPH3 Golgi phosphoprotein 3 1 AAGGGAGS(0.932)S(0.068)EDDAQSRR;AAGGGAGS(0.5)S(0.5)EDDAQSRR 92.439 0.00093791 6711600.0 9725.3 8083.099999999999 16284.2 16098.0 15353.5 14264.9 9976.699999999999 15740.7 12194.599999999999 15272.0 True False 12817.743101193488 10695.80400136433 16068.260868092744 12386.854811620713 13221.931545701198 13372.91354796214 10864.60697257116 13308.336500301999 12839.181660230684 14737.33192843502 0.8697465160883178 0.7257625771953509 1.090310033466082 0.840508639675872 0.8971726775177042 0.9074175442950908 0.7372166838156362 0.9030356759912669 0.8712012270998701 1.0 13.847187739665703 -9.236168492295398 2.0014116880773742 0.9999995438326025 0.8710327056589233 0.14048513272620244 0.09542668460404573 35.86213410674089 97.48770446678951 0.08983119774901548 0.024751668319922933 5.805391433026463e-10 9.236168492295398 -0.12896683817367915 AAGGGAGS(ph)SEDDAQSRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAGGGAGSSEDDAQSRR 17 1 D6REM1;Q9H4A6 D6REM1 GOLPH3 Golgi phosphoprotein 3 1 AAGGGAGS(0.5)S(0.5)EDDAQSRR 85.176 0.0015035 2719400.0 8166.9 8014.0 10198.0 9636.2 10422.0 13626.0 10447.0 8350.6 9403.0 10768.0 True False 9549.394866372384 8809.576957319112 10441.158996130367 9096.314954981917 8379.883914952998 12911.428572797924 9457.384530269854 8131.40559819206 9540.5010862717 12720.153160558897 0.7507295506458197 0.6925684656561193 0.8208359494054712 0.7151104896430542 0.6587879728473963 1.015037194114306 0.7434961207538099 0.6392537491926539 0.7500303625158953 1.0 13.634828421449114 AAGGGAGS(ph)SEDDAQSRR ddPTM_PC-9_Lapatinib_30min_R1 2 AAGGGAGSSEDDAQSRR 17 1 D6REM1;Q9H4A6 D6REM1 GOLPH3 Golgi phosphoprotein 3 1 AAGGGAGS(0.963)S(0.031)EDDAQS(0.007)RR;AAGGGAGS(0.5)S(0.5)EDDAQSRR 104.44 0.00036141 4726200.0 14303.8 9888.7 11831.099999999999 9171.9 11771.7 9668.7 10872.4 9957.8 12399.9 8509.7 True False 14099.825189004343 9865.803322709915 10858.392627366698 9846.432122561466 11079.31175005266 9255.192239840542 11435.319672938227 10420.475740736143 11003.292685264272 9980.590306537497 1.4127245739932497 0.9884989784870346 1.0879509421656375 0.986558091269596 1.1100858175488355 0.9273191219739975 1.1457558442658298 1.0440740898772802 1.1024691273077187 1.0 13.28490943160024 -4.755918624189166 24.999984303783155 1.0462462398465457 1.4127251543210553 0.7444651372908686 0.06485560528055136 82.05053705830741 371515.69583689066 0.014826605891418765 0.12544740389431175 1.7542091655160863e-05 4.755918624189166 0.36647891447450953 AAGGGAGSS(ph)EDDAQSRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAGGGAGSSEDDAQSRR 17 1 D6REM1;Q9H4A6 D6REM1 GOLPH3 Golgi phosphoprotein 3 1 AAGGGAGS(0.003)S(0.996)EDDAQS(0.001)RR 151.56 2.4305e-12 0.0 1258.6 2222.3 2195.8 2696.0 2405.5 2634.2 2346.1 2439.1 1535.5 2102.8 True False 1471.6561215168897 2442.915257330952 2248.156199617874 2544.951860549931 1934.1595430262348 2496.0579147559274 2123.8604237069103 2375.076209440072 1557.9537826193985 2484.02099424436 0.592449147944729 0.9834519365944763 0.9050471814960501 1.024529126946492 0.7786405781222501 1.0048457402491597 0.8550090472777946 0.9561417616611454 0.6271902637816991 1.0 11.278461651523312 -4.752380483626519 24.994030248410233 0.9040243864557088 0.5924485447104956 0.38798880445746775 0.11733900683884138 356.97444156319204 984841.6998343742 0.027294625387574455 0.32699683742137464 1.7685588521894684e-05 4.752380483626519 -0.31157584174521324 AAGGGAGSSEDDAQS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 AAGGGAGSSEDDAQSR 16 0 D6REM1;Q9H4A6 D6REM1 GOLPH3 Golgi phosphoprotein 3 1 AAGGGAGSSEDDAQS(1)R 152.94 1.1945e-10 0.0 2309.0 2603.2 2567.0 2552.0 2156.0 2458.9 2199.6 2830.2 2027.4 2635.4 True False 2276.07323658126 2597.172450340132 2355.951168906552 2739.6825932224365 2029.188318859089 2353.738578975861 2313.484525274541 2961.701424153067 1799.0528625315367 3090.9253785502333 0.7363727550254962 0.8402572473484653 0.7622154793046433 0.8863632270887938 0.6564986437203666 0.7614996451580005 0.7484763434695589 0.9581924703540473 0.5820434472524743 1.0 11.59382310958128 -10.583604563200602 4.691259227970711 1.0000087584333492 0.776742965734202 0.31144759467695105 0.10208494032838568 134545345.23160344 5.0494104922742995 12729.057635140993 0.02297210160282185 2.6085276035140636e-11 10.583604563200602 -0.22326579269914726 AAGGGAGSSEDDAQSR ddPTM_PC-9_Lapatinib_30min_R1 2 AAGGGAGSSEDDAQSR 16 0 D6REM1;Q9H4A6 D6REM1 GOLPH3 Golgi phosphoprotein 3 0 ; 173.19 1.7060999999999996e-21 971960.0 2004.12 2369.9 8559.8 3397.7 5406.9 6625.3 1650.04 1557.8200000000002 7170.0 2134.3 False True 1975.5408812894032 2364.4126421562232 7856.04628578353 3647.5781923949326 5088.876772374397 6341.951363328628 1735.4709974922746 1630.20200430151 6362.439096552785 2503.2109112240128 0.7892027285561043 0.944551907933351 3.138387680621807 1.457159752715903 2.0329396734237037 2.5335265737666344 0.6932979517269957 0.6512443665821106 2.5417111550707077 1.0 11.289564136917983 -7.27299405948729 24.96940571177649 1.1925004600234446 1.830015656954344 0.11249130131250396 0.8157137966357652 1716.4789847546301 3709258.6477616923 0.3462104833755007 0.23565611464274216 5.333421907780886e-08 7.27299405948729 0.6375151969308994 AAGHPGDPESQQR ddPTM_PC-9_AZD4547_30min_R2 1 AAGHPGDPESQQR 13 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 84.169 0.015619 0.0 4282.8 967.07 7773.8 11043.0 8456.6 5531.6 5121.0 11050.0 5063.2 7100.1 False True 5644.641312225994 1279.6564654154224 7670.714332689312 8497.206962649243 7282.547061541456 5185.708177548204 5576.7590793084755 9342.476403739174 5330.830415272335 6851.527660102247 0.8238514959365657 0.18676951023158037 1.11956263087973 1.2401915870719022 1.0629085107470437 0.7568688962237681 0.8139438904673783 1.3635610723929785 0.7780499006542406 1.0 12.74220998104654 -5.277385592952857 24.966107679881194 1.0229547811779534 0.5053104797157362 0.4311578035525041 0.23496026630319788 618.9699859197591 969086.9331755028 0.06059201862003996 0.1267825931383953 5.2797627428880696e-06 5.277385592952857 -0.5176443014622172 AAGHPGDPESQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AAGHPGDPESQQR 13 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 ; 110.64 0.00058861 0.0 11268.9 11123.5 15839.0 12952.0 18989.2 11430.099999999999 15607.5 12069.6 11314.6 7612.1 False True 13176.502199079667 12227.767567349525 16216.661829742008 12226.341430950564 15268.402575112783 10830.685434458932 14129.044611485277 11752.785788798281 11480.054619879811 8992.113472649553 1.465339849097475 1.3598324358941365 1.8034316269547386 1.3596738373173616 1.6979770797547447 1.2044649422409521 1.5712707201104872 1.3070103957813255 1.2766803549351984 1.0 13.134444525892174 -8.556339946639506 0.615768857426366 0.9929946117540579 1.5194739315014472 0.47076844036326715 0.16433229586023024 0.7600014306646746 0.6668887651608426 0.16195093918803163 0.0682560338773497 2.777538281694088e-09 8.556339946639506 0.5264793197473893 AAGHPGDPESQQR ddPTM_PC-9_Lapatinib_30min_R1 1 AAGHPGDPESQQR 13 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 134.49 7.4922e-05 0.0 5055.7 6652.7 9383.4 7363.6 6285.9 10049.0 4842.7 4694.2 10869.0 5286.6 False True 4983.604790898166 6637.296081890668 8611.933072971467 7905.143708249505 5916.175720554892 9619.227695363134 5093.431310486917 4912.309669019621 9644.818764355958 6200.381766048292 0.8037577328201168 1.0704657120041878 1.3889359394171847 1.274944673816063 0.9541631376555489 1.5513928106871693 0.821470596919894 0.7922592276363005 1.555520148318693 1.0 12.598141331617795 -6.228484845542957 24.881156103815904 1.1094768213421045 1.1481223315845193 0.00046081590316937593 0.2850647543035361 8044.946075369471 6074058.7862004945 0.08534915585648603 0.11017813438818368 5.909015843871676e-07 6.228484845542957 0.038645510242414804 AAGISLIVPGKS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 1 AAGISLIVPGKSPTR 15 1 J3KPC5;P47736-3;F2Z357;P47736;P47736-4 J3KPC5;P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 AAGISLIVPGKS(0.638)PT(0.362)R 110.37 0.00025189 101990000.0 75523.0 92428.0 112820.0 148770.0 128590.0 108400.0 98209.0 117770.0 96818.0 123760.0 True False 99537.7430240131 122303.54347194797 111323.93308472165 114473.37497358769 110737.49812496937 101621.73086380535 106949.4107439576 99571.35258537234 101935.60182213545 119427.20006961231 0.8334595717390516 1.024084491645614 0.9321488992443313 0.9585201269632285 0.9272385022877715 0.8509094310556689 0.8955197030627731 0.8337409947426859 0.8535375673441119 1.0 16.865771928598164 -6.618766450898249 5.713491286791185 0.8771780838821527 0.9429071702455643 0.12383950802917587 0.06124561321314444 0.32595353492458773 15.977662284887526 0.01920559680031627 0.019182122206661854 2.4056561339326026e-07 6.618766450898249 0.06572908636341157 AAGISLIVPGKS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AAGISLIVPGKSPTR 15 1 J3KPC5;P47736-3;F2Z357;P47736;P47736-4 J3KPC5;P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 AAGISLIVPGKS(0.753)PT(0.247)R;AAGISLIVPGKS(0.746)PT(0.254)R 69.024 0.01255 173905000.0 117408.0 111172.0 143962.0 185758.0 207802.0 201345.0 196298.0 193811.0 195305.0 158833.0 True False 137282.85548629824 122208.42144984752 147394.60005892566 175350.5814955618 167084.68981913832 190786.11375238496 177703.2323655513 188723.66660972885 198160.96614424064 187628.1655786635 0.7316750929313015 0.6513330292013721 0.7855675591366914 0.9345642801269393 0.8905096380590457 1.0168308855122152 0.9471031804713181 1.0058386811366338 1.0561365642151483 1.0 17.517516886994905 -5.757927136780666 1.0214519449793167 1.0015236022298826 0.662328847188206 0.8803181491371153 0.04456704296688231 0.1955974819432477 0.38593785378322126 0.017121422611551553 0.051155699125343 1.7461150806441497e-06 5.757927136780666 -0.3391947550416766 AAGISLIVPGKS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 2 AAGISLIVPGKSPTR 15 1 J3KPC5;P47736-3;F2Z357;P47736;P47736-4 J3KPC5;P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 AAGISLIVPGKS(0.747)PT(0.253)R;AAGISLIVPGKS(0.747)PT(0.253)R 100.27 0.00089708 123379000.0 160591.0 127482.0 144197.0 139671.0 143665.0 157016.0 147783.0 154492.0 181469.0 140463.0 True False 158300.94289121765 127186.8232614705 132341.67927651695 149942.87126879732 135214.9071562574 150300.791702173 155434.48063222738 161670.26232077437 161030.05026671372 164741.84239481713 0.9609030747139313 0.772037154693566 0.8033276631649501 0.9101687166363426 0.8207684531790288 0.9123413306375743 0.9435033527166468 0.981355191678132 0.977469038380621 1.0 17.32984750277835 -7.211734069579748 1.4005187671556731 0.9876823610277681 0.8473990813501644 0.5586451614862402 0.05137623734206341 0.31240513902764716 1.203251754039304 0.029816625122135447 0.018244369384680482 6.141379435577451e-08 7.211734069579748 -0.14028327967760368 AAGMS(ph)SPGAQSHPEELPR ddPTM_PC-9_AZD4547_30min_R2 1 AAGMSSPGAQSHPEELPR 18 0 M0R300;M0R0P8;Q13459-2;Q13459;M0QZY4;M0R2J3 M0R300 MYO9B Unconventional myosin-IXb 1 AAGMS(0.5)S(0.5)PGAQSHPEELPR 101.9 0.00034491 16445000.0 14711.0 14764.0 23556.0 36870.0 26834.0 15467.0 15614.0 25789.0 15796.0 19241.0 True False 19388.79199219124 19536.174274244157 23243.632048783023 28370.19113582156 23108.562288556106 14499.846044930597 17003.615751674002 21803.902622265094 16630.944311826854 18567.3784465046 1.044239608087553 1.0521773082037833 1.251853195956091 1.5279588993976898 1.244578622401398 0.7809312492179133 0.91577902613791 1.1743123933777406 0.8957077252312757 1.0 14.18048251312032 -6.735964335967073 24.98739618672338 0.9618926605914896 1.2330230360873036 0.4304014519724334 0.15545029493995408 244.09136272362045 239418.32731847398 0.056359439425996125 0.05633962906537682 1.8366891650974074e-07 6.735964335967073 0.271130375495814 AAGMS(ph)SPGAQSHPEELPR ddPTM_PC-9_Lapatinib_30min_R1 3 AAGMSSPGAQSHPEELPR 18 0 M0R300;M0R0P8;Q13459-2;Q13459;M0QZY4;M0R2J3 M0R300 MYO9B Unconventional myosin-IXb 1 AAGMS(0.5)S(0.5)PGAQSHPEELPR;AAGMS(0.757)S(0.243)PGAQSHPEELPR;AAGMS(0.5)S(0.5)PGAQSHPEELPR 99.846 0.00035365 26269500.0 93675.0 73239.0 113677.0 82319.0 88844.0 99766.0 64299.0 72627.0 108296.0 64437.0 True False 92339.1773221087 73069.41959529057 104330.91586590964 88373.01386813378 83618.37059402445 95499.24074590503 67628.08760257662 76001.5155578987 96098.56407256353 75574.84959309468 1.2218241626582846 0.9668483627649451 1.380497830000874 1.1693442242220284 1.1064311876799913 1.2636378538638977 0.8948491193392443 1.0056456078589802 1.271568049291151 1.0 16.20561858219486 -7.2435204283192105 24.985690074382536 1.0434861386573295 1.1794941986495344 0.21317265914409667 0.1331807839086301 1369.5702774093677 1909693.642330006 0.05046791940855273 0.03900149091448057 5.7079422655393854e-08 7.2435204283192105 0.1360080599922049 AAGMSS(ph)PGAQSHPEELPR ddPTM_PC-9_AZD4547_30min_R2 1 AAGMSSPGAQSHPEELPR 18 0 M0R300;M0R0P8;Q13459-2;Q13459;M0QZY4;M0R2J3 M0R300 MYO9B Unconventional myosin-IXb 1 AAGMS(0.248)S(0.752)PGAQSHPEELPR 88.98299999999999 0.0010306 18927000.0 16388.0 14436.0 17111.0 31791.0 27364.0 21563.0 15857.0 24393.0 15644.0 16705.0 True False 21599.043108424295 19102.154688633727 16884.096959871218 24462.07611605378 23564.980937022032 20214.662201256768 17268.242280920625 20623.622345376418 16470.909902141022 16120.163034606281 1.3398774604237016 1.1849852044067914 1.0473899627209071 1.517483170830179 1.461832667971995 1.2539986201045572 1.0712200766114885 1.2793680995100511 1.0217582704828585 1.0 13.976578714484098 -8.050838513600446 0.9725633128989577 1.0001588031052495 1.293258051973176 0.351203832702891 0.14109384341099582 0.6821356878956706 1.2304791891697957 0.14160141595804798 0.05217165476513788 8.895318164806497e-09 8.050838513600446 0.2930992488679265 AAGMSS(ph)PGAQSHPEELPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAGMSSPGAQSHPEELPR 18 0 M0R300;M0R0P8;Q13459-2;Q13459;M0QZY4;M0R2J3 M0R300 MYO9B Unconventional myosin-IXb 1 AAGMS(0.267)S(0.733)PGAQSHPEELPR 108.12 0.00019384 14863000.0 38266.0 35146.0 40987.0 47511.0 54349.0 56110.0 54065.0 44746.0 49636.0 35661.0 True False 44743.67801204935 38635.06260817785 41964.28552406311 44849.11270274024 43699.70359756095 53167.49282399023 48943.57180329662 43571.46491230592 50361.83259791369 42126.05700767934 1.0621378118510554 0.9171298087816502 0.9961598237502566 1.064640649718641 1.0373556582709542 1.2621046592207312 1.1618360530247227 1.0343114928692019 1.1955031202833206 1.0 15.362425265739624 -6.177932508187199 1.842256546632648 1.1315928600070961 0.9871908587408849 0.3196596259009812 0.0812961140496363 0.3796272591854539 2.5417724893868323 0.02752933122433352 0.03870223882486302 6.638462278353397e-07 6.177932508187199 -0.14440200126621128 AAGPAS(ph)PPEEDPER ddPTM_PC-9_AZD4547_30min_R2 3 AAGPASPPEEDPER 14 0 Q96KM6 Q96KM6 ZNF512B Zinc finger protein 512B 1 AAGPAS(1)PPEEDPER;AAGPAS(1)PPEEDPER;AAGPAS(1)PPEEDPER 138.31 2.5166999999999998e-05 0.0 41530.0 52293.0 50648.0 67113.0 62520.0 51175.0 43902.0 56928.0 44365.0 46887.0 True False 54735.6761223372 69195.68960464979 49976.37442718469 51641.13473551375 53840.177173754484 47975.01916010365 47809.1929505567 48131.08567529985 46710.043327057414 45245.5004012921 1.2097484973505583 1.5293385859574609 1.1045600995443403 1.14135404134107 1.1899564972479992 1.0603268553691054 1.0566618233089846 1.063776182126728 1.0323688082301217 1.0 15.465486704971399 -5.650489144818491 0.7185043382428445 1.0413740879374724 1.4005857560892243 0.5406559552156073 0.09832651072618397 0.8586660413298379 0.7066392772901396 0.04787096989055948 0.21041181528122677 2.2362010918236037e-06 5.650489144818491 0.3592116681517519 AAGPAS(ph)PPEEDPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAGPASPPEEDPER 14 0 Q96KM6 Q96KM6 ZNF512B Zinc finger protein 512B 1 AAGPAS(1)PPEEDPER 126.32 0.00067123 0.0 10122.0 10264.0 15545.0 15703.0 25365.0 12000.0 14850.0 13727.0 14305.0 8882.3 True False 11835.454681387224 11282.942087587131 15915.651754740797 14823.211819812896 20394.910334176035 11370.698875207325 13443.300495310354 13366.68079495874 14514.183562598828 10492.59067775189 1.1279821204197638 1.0753247157073489 1.516846720084847 1.412731352538463 1.9437440152335939 1.0836884068409667 1.2812184243320424 1.273916157169932 1.3832793071185152 1.0 13.357083310705384 AAGS(ph)PSPLPAPDPAPK ddPTM_PC-9_AZD4547_30min_R2 1 AAGSPSPLPAPDPAPK 16 0 J3KRY8;Q9BZE9-3;Q9BZE9;Q9BZE9-2;J3KRF7 J3KRY8 ASPSCR1 Tether containing UBX domain for GLUT4 1 AAGS(0.984)PS(0.016)PLPAPDPAPK 180.7 3.6849e-06 37096000.0 115270.0 113220.0 146480.0 200260.0 186060.0 162690.0 149420.0 177740.0 149040.0 163540.0 True False 151923.4622350547 149816.15086222702 144537.57949166815 154093.15098615753 160228.78062937834 152516.96858148027 162718.09053510503 150274.36705887795 156917.95012880937 157814.51437770217 0.9626710371610798 0.9493179474206509 0.9158700013215645 0.9764193844513047 1.0152981255317115 0.9664318214512061 1.0310717691382112 0.9522214585359483 0.9943188733151184 1.0 17.26787037216951 -5.9583744243678005 8.112291425118407 0.991798593191245 0.9435531080378567 0.4794292579251882 0.02354572036382614 0.20996741403872698 35.827546270312816 0.006382650375919221 0.009461273806334975 1.1005900333356294e-06 5.9583744243678005 -0.04824548515338822 AAGS(ph)PSPLPAPDPAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AAGSPSPLPAPDPAPK 16 0 J3KRY8;Q9BZE9-3;Q9BZE9;Q9BZE9-2;J3KRF7 J3KRY8 ASPSCR1 Tether containing UBX domain for GLUT4 1 AAGS(0.949)PS(0.051)PLPAPDPAPK;AAGS(0.69)PS(0.31)PLPAPDPAPK 177.39 8.5257e-06 47112000.0 214524.0 227737.0 235748.0 270960.0 312330.0 302180.0 291710.0 287400.0 289060.0 221033.0 True False 250838.67615786582 250345.22429859973 241369.12639926904 255778.98966417217 251131.17857966555 286333.14884251234 264077.1170024903 279856.0545254714 293286.9556522061 261104.5332037341 0.9606829612649502 0.9587930980243107 0.9244156868426869 0.9796037875167547 0.9618032115272139 1.0966226642227346 1.0113846502865456 1.0718161461681934 1.1232549356902997 1.0 17.994267979861498 -6.747287912740847 24.377986612471858 1.0620272402395081 0.9565948879491194 0.6722209210311136 0.03614848551687275 101.72676782317004 175238.9315840702 0.011706769535708162 0.011648903233245429 1.7894191767643186e-07 6.747287912740847 -0.10543235229038872 AAGS(ph)PSPLPAPDPAPK ddPTM_PC-9_Lapatinib_30min_R1 1 AAGSPSPLPAPDPAPK 16 0 J3KRY8;Q9BZE9-3;Q9BZE9;Q9BZE9-2;J3KRF7 J3KRY8 ASPSCR1 Tether containing UBX domain for GLUT4 1 AAGS(0.936)PS(0.064)PLPAPDPAPK 99.069 0.001964 29292000.0 115620.0 103820.0 124950.0 97058.0 111570.0 121850.0 105730.0 114230.0 118070.0 89424.0 True False 113971.23759788903 103579.61116868179 114677.09332094794 104195.96909599667 105007.67195505959 116638.75954622343 111204.18205913687 119537.54281711728 104771.7132677806 104880.81925000981 1.0866737923376621 0.9875934599802633 1.09340386679843 0.9934702059069482 1.0012094938422191 1.1121076320750853 1.0602909364585886 1.139746463384973 0.9989597146264739 1.0 16.678391334400786 -6.751265107830823 24.99946644306822 1.0708344817516124 1.0311955615588169 0.06163230426950195 0.05283770470134496 454.1815607996246 1115980.1677370763 0.016583898446774943 0.01640259619169379 1.773106786970669e-07 6.751265107830823 -0.03963892019279558 AAGSPS(ph)PLPAPDPAPK ddPTM_PC-9_AZD4547_30min_R2 5 AAGSPSPLPAPDPAPK 16 0 J3KRY8;Q9BZE9-3;Q9BZE9;Q9BZE9-2;J3KRF7 J3KRY8 ASPSCR1 Tether containing UBX domain for GLUT4 1 AAGSPS(1)PLPAPDPAPK;AAGS(0.005)PS(0.995)PLPAPDPAPK;AAGS(0.001)PS(0.999)PLPAPDPAPK;AAGSPS(1)PLPAPDPAPK;AAGS(0.387)PS(0.613)PLPAPDPAPK 192.4 5.8401e-09 82484000.0 222566.0 221266.0 302851.0 421555.0 345044.0 318978.0 297431.0 357769.0 299402.0 324668.0 True False 293337.35833961226 292785.9074075392 298834.99786067184 324372.00770982506 297140.59649297677 299032.25523500773 323901.78279980464 302484.0217637432 315227.77847870294 313301.4721412486 0.9362782636634541 0.9345181349021553 0.9538257060150209 1.035335089531866 0.9484174921432037 0.9544553148482886 1.0338342191184375 0.9654727113039914 1.0061484113824588 1.0 18.257192023098504 -5.536620605671747 24.722045646624448 0.9893204021915265 0.9375916179720557 0.4086985527786824 0.02822157503655637 192.5306359604432 346367.52033239446 0.007568006989806862 0.01311650841361775 2.9065606814405552e-06 5.536620605671747 -0.0517287842194708 AAGSPS(ph)PLPAPDPAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AAGSPSPLPAPDPAPK 16 0 J3KRY8;Q9BZE9-3;Q9BZE9;Q9BZE9-2;J3KRF7 J3KRY8 ASPSCR1 Tether containing UBX domain for GLUT4 1 AAGSPS(1)PLPAPDPAPK;AAGSPS(1)PLPAPDPAPK;AAGS(0.029)PS(0.971)PLPAPDPAPK;AAGSPS(1)PLPAPDPAPK 218.2 3.3710000000000004e-22 28387000.0 179400.0 177413.0 192192.0 246144.0 249556.0 234590.0 267902.0 250599.0 223219.0 191270.0 True False 209768.87668848716 195025.3901583298 196774.58617221925 232353.34968961452 200657.29325273537 222287.68742790702 242524.38311748405 244021.04178158817 226483.15558614145 225945.73690751262 0.9284037820742456 0.8631514487841849 0.8708931129458126 1.0283590780237857 0.8880773587459688 0.9838100531141999 1.0733744590045424 1.0799984329045977 1.002378529845194 1.0 17.78561681126245 -6.990482249127043 4.104270444090136 1.04470171457926 0.9170134085943713 0.579364615241164 0.049383430233386164 0.1536321683050642 6.035857006798943 0.019222857921173835 0.015962425721390564 1.0221573382763095e-07 6.990482249127043 -0.12768830598488878 AAGSPS(ph)PLPAPDPAPK ddPTM_PC-9_Lapatinib_30min_R1 3 AAGSPSPLPAPDPAPK 16 0 J3KRY8;Q9BZE9-3;Q9BZE9;Q9BZE9-2;J3KRF7 J3KRY8 ASPSCR1 Tether containing UBX domain for GLUT4 1 AAGS(0.467)PS(0.533)PLPAPDPAPK;AAGSPS(1)PLPAPDPAPK;AAGS(0.001)PS(0.999)PLPAPDPAPK 185.86 6.2835e-08 28721700.0 261462.0 222668.0 246509.0 234445.0 232349.0 236475.0 241760.0 220717.0 259498.0 204279.0 True False 257733.50393374168 222152.42592668068 226241.98157225776 251686.8673855932 218682.68863571004 226361.51550014925 254277.14985923472 230972.317587023 230270.60260491693 239588.35296534188 1.0757346955468432 0.927225481444069 0.9442945734719635 1.050497089155254 0.9127434031292164 0.9447934872397324 1.0613084764434173 0.9640381710058951 0.9611093350528069 1.0 17.870198250979378 AAGVNVEPFWPGLFAK ddPTM_PC-9_Lapatinib_30min_R1 2 AAGVNVEPFWPGLFAK 16 0 P05386 P05386 RPLP1 60S acidic ribosomal protein P1 0 ; 98.182 0.0096101 19414200.0 36788.0 30729.0 40093.0 33016.0 33249.0 36752.0 32004.0 31006.0 36885.0 35393.0 False True 36263.396373907046 30657.848888484128 36796.70830345557 35444.106778147325 31293.359190049094 35180.20263309645 33661.01052322535 32446.651952967997 32730.62288373075 41510.63289179194 0.8735929531220795 0.7385541186134559 0.8864405512528701 0.8538560920172293 0.7538636973236044 0.847498584875895 0.810900922926696 0.7816467659635178 0.7884876862526157 1.0 15.341193307706076 -10.434574203541514 6.57673488558542 1.0000000129399882 0.814037789724504 0.5775969266596643 0.04746012169766863 8.687671661581875e-09 1.4034376850197338e-09 0.04424409226674943 0.010730767772577138 3.6764257261320107e-11 10.434574203541514 -0.18596222321548417 AAHSEGNTTAGLDMR ddPTM_PC-9_AZD4547_30min_R2 4 AAHSEGNTTAGLDMR 15 0 P78371;P78371-2 P78371 CCT2 T-complex protein 1 subunit beta 0 ;;; 127.07 1.4802999999999999e-05 15920100.0 25581.6 17997.3 43243.6 54629.0 40169.9 41416.2 30548.3 45301.8 30129.5 38960.6 False True 33716.01666966485 23814.5752686165 42670.16160913372 42035.12805963646 34593.00276794623 38826.438466803804 33267.03952010139 38301.44774180189 31722.08385940666 37596.60125268368 0.8967836332614819 0.6334236200916324 1.1349473140497743 1.1180565971142393 0.9201098401275554 1.0327113934010814 0.8848416721638305 1.018747611901964 0.8437487113849769 1.0 15.198314627156499 -5.260042920307935 24.998576371476446 0.9940698754244338 0.7651036316555049 0.42831277480104457 0.10584569337091913 109.98161707293286 1968773.5037734953 0.026993103195282805 0.06392604565747481 5.494865667018753e-06 5.260042920307935 -0.22896624376892893 AAHSEGNTTAGLDMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AAHSEGNTTAGLDMR 15 0 P78371;P78371-2 P78371 CCT2 T-complex protein 1 subunit beta 0 ;; 113.43 0.00014581 11646300.0 28043.3 29702.9 35952.1 36454.4 37643.4 32907.9 39185.4 33192.9 32688.4 24952.600000000002 False True 32790.47680957778 32651.607612372576 36809.334413098506 34411.97815475941 30267.445995407925 31182.151792952915 35473.47523427171 32321.62154578463 33166.40600962288 29476.30885532709 1.1124349717774022 1.1077237578365118 1.2487769277273724 1.1674452972947569 1.0268397628741042 1.057871660457837 1.2034571699047991 1.0965287989219628 1.1251885767789713 1.0 14.847268255084115 -6.206653199720524 24.982323722826138 1.094375687120728 1.1618317368857372 0.23712567303799637 0.06372750794196509 522.4333566816819 238227.36156913292 0.019473344445970254 0.025139967668509 6.21365019226388e-07 6.206653199720524 0.06745604976500919 AAHSEGNTTAGLDMR ddPTM_PC-9_Lapatinib_30min_R1 3 AAHSEGNTTAGLDMR 15 0 P78371;P78371-2 P78371 CCT2 T-complex protein 1 subunit beta 0 ;; 96.48899999999999 0.0017875 12839300.0 26852.9 22708.7 29620.4 29009.0 26706.7 30239.300000000003 24581.1 24740.6 31095.8 22930.7 False True 26469.972721781243 22656.119400368363 27185.1250500505 31142.418631187167 25135.864413392414 28946.03563025121 25853.789081753985 25890.138596000776 27593.46355070935 26894.24094176287 0.9842245698288961 0.8424152757993137 1.0108158512046321 1.1579586387518188 0.9346188452695852 1.0762912287776152 0.9613132096844863 0.9626647821019976 1.0259989716928835 1.0 14.71500965068518 -5.364579715015079 8.663406316535495 1.0175252560002332 0.9136424661095607 0.26645365014591715 0.06831432710954574 0.3817878509051317 28.88616906523235 0.017524026066254455 0.03658410294747017 4.31936878066075e-06 5.364579715015079 -0.10388278989067257 AAHTEDINACT(ph)LTTSPR ddPTM_PC-9_AZD4547_30min_R2 1 AAHTEDINACTLTTSPR 17 0 P04049;P04049-2;H7C155 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 AAHTEDINACT(0.538)LT(0.264)T(0.132)S(0.067)PR 186.15 6.0782e-08 64317000.0 85089.0 81026.0 124290.0 172700.0 119050.0 113360.0 70622.0 126780.0 97218.0 100850.0 True False 112145.53203885272 107216.06995021048 122641.83339035668 132886.68318840198 102521.96245258272 106271.58127971357 76907.22118705777 107189.06411457466 102356.74500551938 97319.27219635106 1.1523465959814028 1.1016941200905375 1.2602008895310572 1.3654714034471016 1.0534600201873143 1.0919890673380743 0.7902568468852706 1.1014166227868036 1.051762335408805 1.0 16.570437910649453 -6.450933961702056 6.855605425926191 1.0074069081146095 1.2148945122677635 0.49023791961810936 0.10328837073455152 0.23662585145951856 19.109586676445055 0.03386916066597345 0.03824161503542649 3.540511735872185e-07 6.450933961702056 0.20748760415315393 AAHTEDINACT(ph)LTTSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAHTEDINACTLTTSPR 17 0 P04049;P04049-2;H7C155 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 AAHTEDINACT(0.353)LT(0.24)T(0.24)S(0.167)PR 89.28299999999999 0.0063133 7058300.0 18988.0 18146.0 22069.0 20365.0 25179.0 30030.0 34491.0 26746.0 26737.0 26048.0 True False 22202.293369905194 19947.41495726386 22595.208657148585 19224.015074220813 20245.355698963853 28455.173935206338 31223.762786784497 26043.945839729477 27127.97804356551 30770.296204145463 0.7215495496892239 0.6482685387531787 0.7343188543665853 0.6247588566154556 0.6579512775777681 0.9247611315282943 1.0147371536377328 0.8463989318445613 0.8816287585788904 1.0 14.909250711105045 -6.764505041237833 24.998275633268264 0.9289821704605686 0.6759937298884453 0.8423547705915029 0.05538410448946103 30.910408889725556 252050.1824069259 0.019297797536330638 0.01774487839586014 1.7198673771098145e-07 6.764505041237833 -0.25298844057212333 AAHTEDINACT(ph)LTTSPR ddPTM_PC-9_Lapatinib_30min_R1 1 AAHTEDINACTLTTSPR 17 0 P04049;P04049-2;H7C155 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 AAHTEDINACT(0.994)LT(0.002)T(0.002)S(0.002)PR 134.29 6.0896999999999996e-05 41055000.0 48285.0 52273.0 66231.0 48258.0 78188.0 79602.0 87840.0 89084.0 117480.0 81480.0 True False 47596.44704561544 52151.965080143564 60785.742839053295 51807.05430396877 73589.1355635225 76197.60802132517 92387.92539557918 93223.16785713108 104248.165280756 95563.70943472453 0.49805985271141584 0.5457298109149513 0.6360755897674046 0.5421205875160795 0.7700531509169607 0.7973487893264806 0.9667678864923657 0.9755080501642501 1.090876085675216 1.0 16.544175234591243 -6.8132461094698 0.844562910254888 1.0474938749286684 0.5298377573422676 0.9462518748725927 0.048084254603526624 0.12056098546943936 0.1859802707449915 0.030558128786109168 0.02729026446279909 1.5372832334629774e-07 6.8132461094698 -0.5176561175864008 AAHTEDINACTLT(ph)TSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAHTEDINACTLTTSPR 17 0 P04049;P04049-2;H7C155 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 AAHTEDINACT(0.242)LT(0.253)T(0.253)S(0.253)PR 122.35 0.00012469 36383000.0 56789.0 59588.0 80712.0 81489.0 94436.0 94093.0 102620.0 120340.0 125580.0 101070.0 True False 66402.25606612315 65503.502836627275 82636.48018196449 76923.4355209027 75931.94371449837 89158.59743874024 92899.09069553878 117181.2025107697 127416.36992598134 119393.19093032017 0.5561645144812035 0.5486368387193554 0.6921372947490155 0.6442866207152171 0.6359821956581553 0.7467645076240124 0.7780937084574296 0.9814730772976709 1.0671996362032374 1.0 16.865361035569073 -7.5012574563186005 1.0620708989474081 1.0547532023066355 0.6101818038427934 0.9236311971154054 0.049501645914130456 0.13676437668801814 0.2867656699431138 0.04111470779919992 0.019369700639366293 3.153134843323962e-08 7.5012574563186005 -0.4445713984638421 AAHTEDINACTLTTS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 AAHTEDINACTLTTSPR 17 0 P04049;P04049-2;H7C155 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 AAHTEDINACTLTT(0.026)S(0.974)PR 260.25 3.9591e-58 19757000.0 21131.0 21931.0 29320.0 39037.0 29469.0 30562.0 24214.0 32600.0 22394.0 25491.0 True False 27850.218447895673 29019.766865920363 28931.197642652332 30037.62276563784 25377.73802196691 28650.953308668046 26368.99909126645 27562.419073474837 23577.701121742903 24598.56784885653 1.1321886143542415 1.1797340009479191 1.1761334164011994 1.2211126659975102 1.0316754283378575 1.1647407070489224 1.0719729397779643 1.1204887716565206 0.9584989364671047 1.0 14.58628670253274 -7.723241774420958 0.6352965649313416 0.9837523819306527 1.169091733239268 0.5676272339580181 0.05407365773343426 0.5394520031576109 0.4417954509897293 0.049631613872618524 0.027095202378714933 1.8912904324472303e-08 7.723241774420958 0.18533935130861534 AAHTEDINACTLTTS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 AAHTEDINACTLTTSPR 17 0 P04049;P04049-2;H7C155 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 AAHTEDINACTLTT(0.002)S(0.998)PR 281.61 1.3737999999999997e-83 12918000.0 14185.0 12469.0 15584.0 12813.0 22013.0 22375.0 20978.0 21924.0 22877.0 14230.0 True False 13982.719298789585 12440.128796593073 14302.743675979631 13755.310762915004 20718.238619223146 21418.07340867252 22064.138193857663 22942.66907749695 20300.351354510185 16689.63653971686 0.837808496638885 0.7453804501367602 0.8569835323820826 0.8241827633682167 1.2413834519355347 1.2833157485307274 1.322026285075228 1.3746655910031085 1.216344724236552 1.0 14.026664916151837 -6.267340151002196 4.952550828213719 1.2672389277160643 0.8109082389466029 0.8163056393307172 0.09798111380005842 0.06849403465608365 5.170755579632399 0.028894500828897135 0.0349728453694778 5.403309555791111e-07 6.267340151002196 -0.45633068876946137 AAHVPENS(ph)DTEQDVLTVKPVR ddPTM_PC-9_AZD4547_30min_R2 2 AAHVPENSDTEQDVLTVKPVR 21 1 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2;H3BS99 H3BSS6 ZNF106 Zinc finger protein 106 1 AAHVPENS(0.986)DT(0.014)EQDVLTVKPVR;AAHVPENS(0.963)DT(0.037)EQDVLTVKPVR 89.913 0.00017924 38519000.0 74507.0 71605.0 103644.0 112523.0 105611.0 105394.0 87313.0 127100.0 102688.0 91471.0 True False 98198.67615812585 94749.91593790652 102269.61284021335 86582.56081302004 90948.73562855701 98803.69651900284 95083.68785230626 107459.61546744304 108115.87803829311 88268.62813160545 1.112498044171651 1.0734268555373683 1.1586179031550474 0.9808984533432247 1.0303630809006754 1.11935235213682 1.0772081753727927 1.2174157199681919 1.2248505536655232 1.0 16.429613155123988 -7.737975679583717 24.49432342724456 1.1658498336394651 1.0776827804301463 0.13881136081516376 0.0740067191569947 260.1182870067461 271544.01190850185 0.034148375662970853 0.019699568026780568 1.82820259230689e-08 7.737975679583717 -0.08816705320931884 AAHVPENS(ph)DTEQDVLTVKPVR ddPTM_PC-9_Lapatinib_30min_R1 2 AAHVPENSDTEQDVLTVKPVR 21 1 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2;H3BS99 H3BSS6 ZNF106 Zinc finger protein 106 1 AAHVPENS(0.952)DT(0.048)EQDVLTVKPVR;AAHVPENS(0.966)DT(0.034)EQDVLTVKPVR 104.16 4.0604e-05 37355000.0 83792.0 97577.0 107293.0 113159.0 109943.0 115487.0 113930.0 114124.0 99666.0 95275.0 True False 82597.11071442904 97351.06645161314 98471.78370295711 121481.09034735819 103476.36889625441 110547.89022334573 119828.73793622876 119426.6176701452 88440.56555049223 111743.1568040426 0.7391692974924159 0.8712038323951414 0.8812332362834646 1.0871456814164684 0.9260197389779745 0.9893034471650649 1.0723586245765846 1.0687600125668244 0.7914629233679629 1.0 16.769826957324888 -5.014782262270336 1.3244635641033196 0.9931687599601727 0.6998040966806884 0.44783064380719806 0.08553107388244764 0.8037321082493131 1.685528085590895 0.02542745669599082 0.2849348486527703 9.665353393551664e-06 5.014782262270336 -0.2933646632794843 AAHVPENS(ph)DTEQDVLTVKPVRK ddPTM_PC-9_AZD4547_30min_R2 1 AAHVPENSDTEQDVLTVKPVRK 22 2 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2;H3BS99 H3BSS6 ZNF106 Zinc finger protein 106 1 AAHVPENS(0.831)DT(0.169)EQDVLTVKPVRK 73.688 0.00033885 14446000.0 54623.0 33472.0 60673.0 93302.0 75027.0 53548.0 52815.0 62865.0 52293.0 70734.0 True False 71991.97777101923 44291.1694193647 59868.43637696606 71792.66540153032 64610.796110289106 50199.63509497272 57515.43268378779 53150.65874398758 55057.10122172463 68257.62418975394 1.0547096917830585 0.6488823768058013 0.8770952269087741 1.051789690217595 0.9465725899083921 0.7354436327203447 0.8426228332222168 0.7786772448485828 0.8066073479010595 1.0 16.05870257966876 -6.742133447231184 24.965676699427753 0.8194595423571964 0.9063842217197114 0.09395617414610247 0.12407329167753918 594.1278646792381 768301.4037595914 0.04135010253963248 0.04129007681103887 1.8107836011210085e-07 6.742133447231184 0.08692467936251502 AAHVPENS(ph)DTEQDVLTVKPVRK ddPTM_PC-9_Lapatinib_30min_R1 1 AAHVPENSDTEQDVLTVKPVRK 22 2 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2;H3BS99 H3BSS6 ZNF106 Zinc finger protein 106 1 AAHVPENS(0.945)DT(0.055)EQDVLT(0.001)VKPVRK 54.292 0.0046074 8264300.0 109590.0 51227.0 82246.0 61438.0 67486.0 64148.0 50572.0 45343.0 74134.0 51560.0 True False 108027.22650365537 51108.3870288775 75484.05135874097 65956.3554711598 63516.60616258085 61404.5395762916 53190.37070930355 47449.801312759744 65784.2482543716 60472.07730061852 1.7863984722507698 0.8451567948428118 1.248246376315055 1.0906910828162535 1.0503460274206786 1.0154197162938132 0.8795856382588582 0.7846563807768254 1.0878450218825002 1.0 15.883981517987007 -4.754378590651391 24.999819345329175 1.0023370624674113 1.7863998262996912 0.770979905413353 0.12854163500341478 121.6503107248219 430684.5497999291 0.033598484106539095 0.3294238940207078 1.7604407356546304e-05 4.754378590651391 0.7840627638322799 AAIPPPVYEEQDRPRS(ph)PTGPSNSFLANMGGTVAHK ddPTM_PC-9_AZD4547_30min_R2 1 AAIPPPVYEEQDRPRSPTGPSNSFLANMGGTVAHK 35 2 H0Y6J6;Q5W012;Q96I25 H0Y6J6 RBM17 Splicing factor 45 1 AAIPPPVY(0.019)EEQDRPRS(0.471)PT(0.208)GPS(0.208)NS(0.095)FLANMGGTVAHK 71.472 1.9672e-06 17755000.0 23999.0 23610.0 32573.0 57645.0 42717.0 37108.0 28796.0 42651.0 30080.0 41673.0 True False 31630.18278978978 31241.470781285847 32141.060737179887 44355.83585637199 36786.4818990926 34787.63089385686 31358.788214756263 36060.26797247774 31669.967390462894 40214.04095427401 0.7865457447003489 0.7768796678953364 0.799249714141545 1.1029937505362237 0.9147671068650184 0.8650618059849462 0.7797969930555662 0.8967083913173665 0.7875350658361768 1.0 15.295411693846674 -14.522878744938087 0.01340275504714034 1.9707882694146468 6.554573598978853e-10 0.11050015339866404 0.09869041521695865 22136.62717403833 22.43311842900384 2017.5356867120215 1344.3917775278765 3.0000000023641852e-15 14.522878744938087 -1.9707882687591893 AAIPPPVYEEQDRPRS(ph)PTGPSNSFLANMGGTVAHK ddPTM_PC-9_Lapatinib_30min_R1 1 AAIPPPVYEEQDRPRSPTGPSNSFLANMGGTVAHK 35 2 H0Y6J6;Q5W012;Q96I25 H0Y6J6 RBM17 Splicing factor 45 1 AAIPPPVY(0.007)EEQDRPRS(0.49)PT(0.155)GPS(0.203)NS(0.133)FLANMGGT(0.011)VAHK 57.222 0.0015032000000000001 12777000.0 19511.0 14992.0 23341.0 12686.0 17976.0 18971.0 13586.0 12549.0 20622.0 11217.0 True False 19232.769562120815 14957.28694510573 21421.993078865537 13618.970759255415 16918.687022175785 18159.65455356095 14289.416603191454 13132.072352376805 18299.333200712907 13155.843504287011 1.4619183905504465 1.1369310481864348 1.6283253196106269 1.0352031593274493 1.2860206961767673 1.380348933737573 1.0861649880933177 0.9981931107722237 1.390966166080481 1.0 13.683416131317319 -1.522878746330459 0.07082313153307646 0.7514937896641384 2.3875401519051795 0.2215681571196768 0.18442769004353765 376.2117648787371 1.9731692894926618 7.874281011952175 61.26406294357662 0.029999999927460184 1.522878746330459 1.636046362241041 AAIPPPVYEEQDRPRSPTGPSNS(ph)FLANMGGTVAHK ddPTM_PC-9_AZD4547_30min_R2 2 AAIPPPVYEEQDRPRSPTGPSNSFLANMGGTVAHK 35 2 H0Y6J6;Q5W012;Q96I25 H0Y6J6 RBM17 Splicing factor 45 1 AAIPPPVY(0.002)EEQDRPRS(0.04)PT(0.04)GPS(0.047)NS(0.619)FLANMGGT(0.251)VAHK;AAIPPPVY(0.004)EEQDRPRS(0.229)PT(0.229)GPS(0.229)NS(0.281)FLANMGGT(0.028)VAHK 50.70399999999999 0.012259 59756000.0 26308.3 20546.2 35205.0 47246.0 46779.0 40143.0 25835.3 31772.0 31327.0 35621.0 True False 34673.79215336583 27187.35734716033 34738.15869746164 36354.16464342352 40284.543314316354 37632.851864075026 28134.59165039218 26862.36744792767 32982.88126466193 34373.91963218859 1.0087238384329156 0.7909297990474562 1.0105963785675454 1.0576089381840696 1.1719508204293614 1.094808281009498 0.8184865721291281 0.7814752502875199 0.9595321574492758 1.0 15.069026750069671 -10.641116347228076 4.032834354784991 1.0000088394658708 0.9649468278297062 0.006484348939650442 0.1255885727440335 36453723.56387434 48093758.20270867 2346.8280554064004 0.03393068142988275 2.2849865748548992e-11 10.641116347228076 -0.035062011636164625 AAISQLRS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 AAISQLRSPR 10 1 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 AAIS(0.019)QLRS(0.981)PR;AAIS(0.003)QLRS(0.997)PR 80.688 0.0081682 7720800.0 26400.0 27867.0 31568.0 39710.0 33675.0 32132.0 31272.0 63299.0 43611.0 41837.0 True False 34794.650845887336 36874.46278111365 31149.38769383522 30555.47301338417 28999.807522811603 30122.780960477754 34055.14741810871 53517.59401631543 45916.18842637895 40372.29936419173 0.8618446656211141 0.9133604813655849 0.7715534706815143 0.7568425255581404 0.718309533504872 0.7461249776423485 0.843527566039847 1.325601832423321 1.1373191309263 1.0 15.301078135970265 -7.668542341257578 6.58529999971771 1.1716399672426285 0.7945884604407749 0.7568234890011067 0.0916487796535693 0.09559692924435746 5.632163503001499 0.04445455501354033 0.0253001690110617 2.1451499656220216e-08 7.668542341257578 -0.3770515068018536 AAISQLRS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAISQLRSPR 10 1 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 AAIS(0.011)QLRS(0.989)PR 63.076 0.041979 0.0 10449.0 9551.0 12224.0 12921.0 18314.0 14621.0 11050.0 16905.0 11454.0 10600.0 True False 12217.809322842817 10499.160159639985 12515.46651977815 12197.078260447199 14725.503168149022 13854.249021200527 10003.264004927916 16461.261662328066 11621.493081160917 12521.69609044617 0.9757311816699326 0.8384774781150179 0.9995024978546818 0.974075570301802 1.1759990868476928 1.1064195234518646 0.798874524079867 1.3146191652812684 0.9281085403460565 1.0 13.612142371176722 -5.705816106697176 2.1802668485826726 1.058067328087358 0.9114587361000114 0.12927412425799956 0.13618749694660093 0.5624045427590364 5.432794753197123 0.03915413620858704 0.07889763587964002 1.9687197281937443e-06 5.705816106697176 -0.14660859198734666 AAISQLRS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 AAISQLRSPR 10 1 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 AAIS(0.026)QLRS(0.974)PR 65.179 0.023348 4415600.0 15481.0 16118.0 15223.0 14815.0 18324.0 14716.0 15846.0 13246.0 18883.0 24748.0 True False 15260.238101132303 16080.679761286963 13971.423702479331 15904.544521391232 17246.2183463701 14086.630984671507 16666.428344926535 13861.457516900406 16756.197693194725 29025.658825362825 0.5257499301892778 0.5540160124543169 0.4813473412107705 0.5479477526103121 0.5941714691175324 0.4853164942586078 0.5741963841442005 0.4775587558683824 0.577289142479448 1.0 14.82504119335163 -8.57018892144997 20.430497119417918 1.0000000002552005 0.5316486052921882 0.9328918679426284 0.03758027818798632 589.5227643296266 254580.20971929663 0.03417202932467404 0.008823180026156811 2.6903642201484462e-09 8.57018892144997 -0.46835139496301237 AAKLS(ph)EGSQPAEEEEDQETPSR ddPTM_PC-9_AZD4547_30min_R2 1 AAKLSEGSQPAEEEEDQETPSR 22 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 AAKLS(0.875)EGS(0.123)QPAEEEEDQET(0.002)PS(0.001)R 58.755 0.004406 5868400.0 11485.0 9709.9 15017.0 25415.0 19886.0 15312.0 11986.0 15791.0 13426.0 13632.0 True False 15136.991097159704 12848.435287556444 14817.864768066507 19555.96440783579 17125.17215734615 14354.538219433445 13052.730780041278 13350.863791081014 14135.670950277756 13154.747829257863 1.1506865273002858 0.9767146777971569 1.1264271242896542 1.4866088397636015 1.3018244347685288 1.0912058829061773 0.992244849499153 1.01490837866059 1.0745679912493793 1.0 13.683295972487603 -6.965724632889417 6.568176441453132 1.0241382370227088 1.2062727054204252 0.3401222039255386 0.12415920137566573 0.25308910676154395 32.447055695184815 0.05076405296388702 0.04422352327612292 1.082119858632819e-07 6.965724632889417 0.1821344683977164 AAKLS(ph)EGSQPAEEEEDQETPSR ddPTM_PC-9_Lapatinib_30min_R1 1 AAKLSEGSQPAEEEEDQETPSR 22 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 AAKLS(0.993)EGS(0.007)QPAEEEEDQETPSR 59.537 0.0039865000000000005 7912500.0 12136.0 9439.1 11816.0 10185.0 15724.0 18209.0 14921.0 17331.0 24929.0 17203.0 True False 11962.938414530166 9417.244343886578 10844.534091079016 10934.038876163995 14799.145234573421 17430.24351725219 15693.536370986285 18136.261529926094 22121.233505992237 20176.515628443383 0.5929139914359488 0.4667428468476902 0.537482997103384 0.5419190844206014 0.7334836949602271 0.8638876919204177 0.7778120196761169 0.898879760207898 1.0963852190022014 1.0 14.300389430128611 -6.882838861359922 0.6548239132098068 1.0260565523148537 0.4893576553905562 0.882422091551969 0.06960266717426242 0.2490486638173144 0.22998427491057896 0.05766341272373355 0.05444760233562215 1.3096677660047856e-07 6.882838861359922 -0.5366988969242975 AAKLSEGS(ph)QPAEEEEDQETPSR ddPTM_PC-9_AZD4547_30min_R2 1 AAKLSEGSQPAEEEEDQETPSR 22 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 AAKLS(0.316)EGS(0.68)QPAEEEEDQET(0.003)PS(0.001)R 62.167 0.0025761 7897000.0 9073.6 6328.4 9615.2 12872.0 11564.0 8517.6 10308.0 10093.0 5765.2 7722.8 True False 11958.816057395581 8373.931541393027 9487.696165539932 9904.559270417552 9958.538209169816 7984.993125512427 11225.392030758007 8533.35876406692 6069.936702110929 7452.427122637373 1.6046874207021324 1.1236515840532686 1.2731015022904764 1.3290380579947736 1.336281193400727 1.0714620880031607 1.5062733047948815 1.1450442417807918 0.8144912526112449 1.0 12.863494646817648 -8.037278146905983 5.4656558171630225 0.9222204078648536 1.3045834983245272 0.5301934591616986 0.1544819088270939 0.1517864133374363 11.921661604707525 0.09774247733961343 0.037679014949176144 9.177446323208276e-09 8.037278146905983 0.38236309045967365 AAKNS(ph)EEEEEEK ddPTM_PC-9_Lapatinib_30min_R1 1 AAKNSEEEEEEK 12 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 AAKNS(1)EEEEEEK 58.885 0.031334 12618000.0 9532.3 13201.0 10936.0 11215.0 10464.0 11124.0 12149.0 14091.0 10353.0 10955.0 True False 9396.367653990272 13170.433895567015 10036.884294180789 12039.788512143274 9848.528093015542 10648.25245131053 12778.015774486448 14745.719301724583 9186.936118076841 12848.557153380065 0.7313169519208134 1.0250515865979766 0.7811682023409445 0.9370537382850005 0.7665084861629536 0.8287508335914044 0.9945097820672371 1.1476556570280292 0.71501694769362 1.0 13.649318738615579 -7.26260781373909 24.938525310354358 0.9766002384534649 0.8508786991432984 0.1698028196380521 0.12770236880279925 175.21983204283958 3739745.731285068 0.04881850921756702 0.03499495251161458 5.462509260873343e-08 7.26260781373909 -0.1257215393101665 AAKPGPAEAPS(ph)PTASPSGDASPPATAPYDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAKPGPAEAPSPTASPSGDASPPATAPYDPR 31 1 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 AAKPGPAEAPS(0.742)PT(0.251)AS(0.006)PSGDASPPATAPYDPR 87.868 2.5719e-09 18956000.0 25795.0 20950.0 25258.0 31900.0 32652.0 29875.0 28280.0 29942.0 28908.0 19605.0 True False 30161.584025526892 23029.777546273446 25860.24651149841 30112.746421195407 26254.074994343227 28308.302408068223 25601.113670530434 29156.05422617138 29330.724811437023 23159.2313069054 1.3023568712547724 0.9944102738594197 1.116628016223822 1.3002480964131429 1.133633264697997 1.2223334200055043 1.1054388347896908 1.2589387721810053 1.266480930336037 1.0 14.49929974824275 AAKPGPAEAPS(ph)PTASPSGDASPPATAPYDPR ddPTM_PC-9_Lapatinib_30min_R1 1 AAKPGPAEAPSPTASPSGDASPPATAPYDPR 31 1 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 AAKPGPAEAPS(0.936)PT(0.061)AS(0.002)PSGDASPPATAPYDPR 90.12700000000001 1.6019e-09 90901000.0 72069.0 54621.0 67030.0 59123.0 70493.0 65614.0 60043.0 52602.0 65708.0 44947.0 True False 71041.28284416396 54494.52843040426 61519.05214328254 63471.10264854627 66346.7403345703 62807.84217370456 63151.73274734467 55046.08095304206 58307.27310408518 52716.02906188712 1.3476220441559341 1.0337373546560047 1.166989495188663 1.204019038953655 1.2585686273273944 1.1914372780235387 1.1979607317009089 1.0442000646220815 1.1060634524583424 1.0 15.685954080159332 -7.759255043651596 24.90812950654689 1.056348794019331 1.1944521481840353 0.4384078275431791 0.07750008852405738 54.34485837799722 619723.5734743387 0.037681553503071584 0.020388934599226187 1.740784280685012e-08 7.759255043651596 0.13810335416470432 AAKPGPAEAPSPT(ph)ASPSGDASPPATAPYDPR ddPTM_PC-9_AZD4547_30min_R2 1 AAKPGPAEAPSPTASPSGDASPPATAPYDPR 31 1 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 AAKPGPAEAPS(0.246)PT(0.606)AS(0.102)PS(0.019)GDAS(0.023)PPAT(0.002)APY(0.001)DPR 48.672 0.009609200000000002 22117000.0 17064.0 15419.0 25712.0 29283.0 30291.0 22388.0 22618.0 27927.0 24778.0 24910.0 True False 22489.99704675083 20402.89021502103 25371.042080077656 22532.25676784007 26085.617510719698 20988.0748208383 24630.958183128125 23611.523848617533 26087.714494710428 24037.908482013892 0.9356054027570131 0.8487797609466429 1.0554596336474642 0.9373634476019238 1.085186655496171 0.8731240006401723 1.0246714351857182 0.9822619911497127 1.0852738920372496 1.0 14.553023753389963 -5.257956409724302 24.98462559620129 1.0011653821637423 0.8921925809550709 0.3253819354061468 0.0649827260905894 327.1109309500299 2346460.4467720566 0.01565372112568177 0.038083798609631854 5.521328542504256e-06 5.257956409724302 -0.10897280120867137 AAKPGPAEAPSPT(ph)ASPSGDASPPATAPYDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAKPGPAEAPSPTASPSGDASPPATAPYDPR 31 1 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 AAKPGPAEAPS(0.011)PT(0.789)AS(0.199)PS(0.001)GDASPPATAPYDPR 104.12 3.0004999999999997e-15 16805000.0 48563.0 46159.0 51143.0 62848.0 71716.0 66407.0 65997.0 59747.0 63523.0 57110.0 True False 56783.75673702898 50741.360465796446 52362.44308090758 59326.830315965126 57663.76461761363 62924.50001715769 59745.28638309756 58178.70455717925 64451.90370129081 67463.5909174887 0.8416948455423654 0.7521295527813755 0.7761585526176545 0.8793903423926064 0.8547390352840728 0.9327179173447416 0.885593037230541 0.8623718922453248 0.9553583321723663 1.0 16.041821490982507 -6.049792949720212 0.17684946462342743 1.0325432969127255 0.6496439852143918 0.6966653231046052 0.039746893018263285 6.169112071243088 0.3377049333995519 0.16066056387488437 0.5881335779602234 8.916759441126391e-07 6.049792949720212 -0.3828993116983337 AAKPGPAEAPSPTASPSGDAS(ph)PPATAPYDPR ddPTM_PC-9_AZD4547_30min_R2 4 AAKPGPAEAPSPTASPSGDASPPATAPYDPR 31 1 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 AAKPGPAEAPS(0.001)PT(0.002)AS(0.004)PS(0.213)GDAS(0.736)PPAT(0.04)APY(0.006)DPR;AAKPGPAEAPSPTASPS(0.014)GDAS(0.931)PPAT(0.053)APY(0.003)DPR;AAKPGPAEAPSPTASPS(0.108)GDAS(0.871)PPAT(0.021)APY(0.001)DPR;AAKPGPAEAPSPTASPS(0.127)GDAS(0.778)PPAT(0.086)APY(0.008)DPR 126.24 8.0295e-18 211326600.0 89894.0 80918.0 112783.0 164373.0 140884.0 127953.0 99670.0 131788.0 97657.0 121100.0 True False 118478.42208864393 107073.1610622654 111287.42372889693 126479.34438753464 121324.68843485622 119952.078682809 108540.43691362548 111423.19278696619 102818.94964928314 116860.32585997148 1.0138464120886617 0.9162490372529544 0.952311427423604 1.0823120974272245 1.038202551139847 1.0264568218519452 0.9288048455699555 0.9534732336830862 0.8798447967061679 1.0 16.83442569173082 -7.269630658706342 24.36363210881218 0.9366534830367699 1.0035095525935454 0.27621208079470516 0.05085964345351871 637.9735957749834 1897539.6776867893 0.02262378651655467 0.015580431537070435 5.3748870381925295e-08 7.269630658706342 0.06685606955677548 AAKPGPAEAPSPTASPSGDAS(ph)PPATAPYDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AAKPGPAEAPSPTASPSGDASPPATAPYDPR 31 1 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 AAKPGPAEAPSPTASPS(0.01)GDAS(0.885)PPAT(0.089)APY(0.017)DPR;AAKPGPAEAPSPTASPS(0.101)GDAS(0.843)PPAT(0.053)APY(0.003)DPR;AAKPGPAEAPSPTASPS(0.147)GDAS(0.836)PPAT(0.014)APY(0.002)DPR 126.15 2.8378999999999997e-16 25788100.0 63044.0 55578.2 65078.0 70146.0 80936.0 71139.0 69781.0 65497.0 72080.0 55896.0 True False 73716.10402424195 61095.63639247226 66629.70632968932 66215.94703640035 65077.17180393735 67408.34560694783 63170.838509309906 63777.77314980788 73134.03363803739 66029.50232750755 1.116411625497474 0.925277856698613 1.0090899367862072 1.0028236576427312 0.9855771967075169 1.020882230379402 0.9567062643601549 0.9658981349498735 1.1075963177079728 1.0 16.010823151770822 -8.245810956031864 24.918415582774276 1.0537981753047774 0.99494526235271 0.14685684891488782 0.05359542555109628 1157.6871611745614 1845858.006175617 0.033813343881943264 0.01267607042462066 5.677917055755442e-09 8.245810956031864 -0.058852912952067404 AAKPGPAEAPSPTASPSGDAS(ph)PPATAPYDPR ddPTM_PC-9_Lapatinib_30min_R1 3 AAKPGPAEAPSPTASPSGDASPPATAPYDPR 31 1 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 AAKPGPAEAPSPTAS(0.001)PS(0.085)GDAS(0.792)PPAT(0.109)APY(0.013)DPR;AAKPGPAEAPSPTASPS(0.114)GDAS(0.806)PPAT(0.075)APY(0.006)DPR;AAKPGPAEAPSPTASPSGDAS(0.985)PPAT(0.014)APYDPR 153.49 3.7037e-16 126025000.0 175218.0 143004.0 148551.0 120589.0 137168.0 142331.0 129831.0 129521.0 160261.0 111255.0 True False 172719.35918895388 142672.8830241394 136337.71020344284 129457.51733311175 129100.04792266391 136243.83491976632 136553.01391203798 135539.01849965716 142210.71855685432 130485.27851203085 1.3236693147191236 1.0934021419970745 1.0448512794558076 0.9921235468810043 0.9893840086394173 1.044131847465111 1.0465013024396286 1.0387303460226 1.0898602522716183 1.0 16.993527524023357 -4.693829100218362 2.1779595128376243 1.030187743059328 1.4493214792355105 0.902171497082126 0.028912032070742694 0.2669324065727346 1.1890579214436552 0.00816974465551582 0.23877085589814592 2.0238154162181073e-05 4.693829100218362 0.41913373617618244 AAKPT(ph)TTPEVK ddPTM_PC-9_AZD4547_30min_R2 1 AAKPTTTPEVK 11 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 AAKPT(0.333)T(0.333)T(0.333)PEVK 65.805 0.031556 51105000.0 161470.0 139800.0 144450.0 159000.0 161280.0 154660.0 136310.0 147460.0 145280.0 162210.0 True False 212814.10121535667 184987.61606199754 142534.49861804667 122345.00652551216 138889.05589544328 144989.085750887 148441.3259325402 124673.44529369909 152959.20420500153 156531.07727288164 1.3595645345515412 1.1817948185426939 0.9105827488145716 0.7816020221481471 0.8872938097354118 0.9262638977314811 0.9483185608807987 0.7964772712600391 0.9771810612300761 1.0 17.256089588952285 -5.096357348455096 2.590705124673549 0.8918930122562254 1.3522717524322756 0.8337215284590002 0.06767667906766782 0.11083321358468257 1.3439111509532564 0.017939261196766566 0.08063274283414833 8.010186937644077e-06 5.096357348455096 0.4603787401760502 AAKPTTT(ph)PEVK ddPTM_PC-9_AZD4547_30min_R2 2 AAKPTTTPEVK 11 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 AAKPT(0.01)T(0.139)T(0.852)PEVK;AAKPT(0.013)T(0.104)T(0.883)PEVK 65.565 0.031989 131068000.0 403680.0 367970.0 361280.0 428500.0 437360.0 409060.0 345083.0 386110.0 363070.0 370720.0 True False 532041.8429343853 486909.1064544581 356489.19114384183 329715.9452590058 376640.1133831297 383481.4135345781 375794.71848564857 326445.57142513467 382261.1389779046 357741.20563838654 1.4872254986253555 1.3610652023872183 0.9965002228571616 0.9216605190073929 1.052828434205722 1.071952035411348 1.0504652876512943 0.9125187881071596 1.0685409814498792 1.0 18.44855677601395 -5.173441455730497 3.5385116552112605 1.0072515751337772 1.4623041014851852 0.9021463934977646 0.05522091008468631 0.06758805598279764 1.5799410383014818 0.015063503570061003 0.04752206899024788 6.707466993843204e-06 5.173441455730497 0.455052526351408 AAKPTTT(ph)PEVK ddPTM_PC-9_Lapatinib_30min_R1 1 AAKPTTTPEVK 11 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 AAKPT(0.035)T(0.035)T(0.931)PEVK 70.438 0.023227 33096000.0 153010.0 120790.0 120380.0 128830.0 119610.0 114680.0 98931.0 85757.0 112890.0 82114.0 True False 150828.0493414024 120510.31817631552 110482.8210802382 138304.5879642815 112574.77496230781 109775.40373213698 104053.16310689921 89741.58329132033 100175.13941559895 96307.29548997266 1.5661123965121244 1.251310376469484 1.1471905686702775 1.4360759199045467 1.1689122240384051 1.139845150605092 1.0804286692666294 0.9318253911580776 1.0401614841944036 1.0 16.555357469087987 -3.3852156683193533 0.23288928643092494 0.9330456925951105 2.403082662571979 0.6861411919918683 0.10418927924438907 13.318527926761124 0.3684515700126012 0.16576261027103215 6.278210271222711 0.0004118929244756144 3.3852156683193533 1.4700369699768685 AALAHSEEVTASQVAATK ddPTM_PC-9_Lapatinib_30min_R1 2 AALAHSEEVTASQVAATK 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 159.14 3.4602e-18 2945100.0 63822.0 65735.0 79317.0 72074.0 70771.0 73691.0 58323.0 58858.0 65759.0 61899.0 False True 62911.88657647859 65582.7946462465 72795.86243247401 77374.56239181572 66608.38892113946 70539.40771211112 61342.67956336929 61592.75755169294 58352.528947031366 72598.1596747669 0.866576878233802 0.9033671781771249 1.002723247511959 1.0657923387927004 0.9174941791849675 0.9716418161027939 0.8449619086513883 0.8484065963603328 0.8037742169835345 1.0 16.147645356672143 -7.260399892926996 24.98415587326441 0.861652894250794 0.9578256317705224 0.22912382231432737 0.07051673206316461 123.36054839359332 2965036.5533068925 0.02865729060213507 0.02092635637075753 5.4903509638688166e-08 7.260399892926996 0.09617273751972832 AALAPAKES(ph)PR ddPTM_PC-9_AZD4547_30min_R2 6 AALAPAKESPR 11 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;H0YAB7;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 AALAPAKES(1)PR;AALAPAKES(1)PR;AALAPAKES(1)PR;AALAPAKES(1)PR;AALAPAKES(1)PR;AALAPAKES(1)PR 126.5 0.0010586999999999999 2614811100.0 448113.0 394909.0 517982.0 627188.0 518850.0 510645.0 475570.0 514897.0 463021.0 515370.0 True False 590603.6126705736 522555.6113836011 511113.22023657383 482599.4965580051 446816.63350291905 478714.2874257174 517894.80869883567 435331.4998059801 487495.3447838939 497327.0531664192 1.1875557722232768 1.050728304556438 1.0277205251199986 0.9703865765703965 0.8984362114590255 0.9625743952149864 1.041356599045767 0.875342487472336 0.9802308997269944 1.0 18.92383538618772 -4.433045267586688 0.9416969524651029 0.956613531213261 1.4589241152116281 0.6888577921371684 0.046250184751295956 2.0294599929069372 0.9151969616971113 0.015488367716695449 1.216127216939475 3.689391411278568e-05 4.433045267586688 0.5023105839983671 AALAPAKES(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AALAPAKESPR 11 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;H0YAB7;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 AALAPAKES(1)PR;AALAPAKES(1)PR;AALAPAKES(1)PR 84.169 0.0057350000000000005 1441270000.0 833620.0 845890.0 972650.0 1054960.0 1068780.0 958230.0 985160.0 1105460.0 928110.0 784020.0 True False 974735.4012544954 929864.3689077431 995841.6647956683 995854.011426469 859360.2313014248 907978.7319324939 891838.5128592579 1076442.8463316897 941681.8529383858 926156.6197010969 1.0524520156958728 1.004003371706011 1.0752411024358506 1.0752544334756964 0.9278778697049861 0.9803727713197475 0.9629456766686884 1.1622686956328137 1.0167630753881556 1.0 19.820896658591593 -8.528567556984452 24.410891678680528 0.9999999817292627 1.0289367077892182 0.021484345967336727 0.06337795317196604 2851.2935608422313 12235007.189610876 0.06372776201460359 0.01645443787583727 2.9609593354506125e-09 8.528567556984452 0.028936726059955453 AALAPAKES(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 6 AALAPAKESPR 11 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;H0YAB7;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 AALAPAKES(1)PR;AALAPAKES(1)PR;AALAPAKES(1)PR;AALAPAKES(1)PR;AALAPAKES(1)PR;AALAPAKES(1)PR 130.15 0.0010783 1986890000.0 458067.0 426307.0 446853.0 430255.0 434115.0 382820.0 351144.0 375736.0 454447.0 335522.0 True False 451534.8805807998 425319.9123337244 410114.4712424611 461897.38798860507 408581.20920292847 366447.6809970065 369324.518159212 393194.0662517061 403262.3933209379 393516.53064503823 1.1474356104955998 1.0808184134896575 1.0421785091727052 1.1737687035192128 1.038282200072248 0.9312129287080737 0.9385235165440915 0.9991805569316147 1.0247660820243678 1.0 18.586064715452167 -6.519494124584758 7.361254295217449 0.9768568863333887 1.1044014524083545 0.6828029708032615 0.04240279411231966 0.07891150814578228 29.44171613925603 0.014089311159318005 0.014830740038471962 3.0234714737025057e-07 6.519494124584758 0.12754456607496578 AALDGGVAS(ph)AASPESKPSPGTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AALDGGVASAASPESKPSPGTK 22 1 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 AALDGGVAS(0.5)AAS(0.494)PES(0.004)KPS(0.001)PGT(0.001)K 42.528999999999996 0.042977 8243000.0 32407.0 24546.0 26813.0 28712.0 29089.0 27215.0 35175.0 28326.0 31982.0 21875.0 True False 37892.86503257416 26982.76466113737 27452.323608868774 27103.359725559952 23389.219267133718 25787.797490730605 31842.96935505332 27582.472513877845 32449.67624600039 25840.76433759528 1.4663987696929108 1.044193751725858 1.0623650001300025 1.0488606053392835 0.905128771021109 0.9979502600552874 1.2322766052521728 1.0674015734801074 1.255755279606413 1.0 14.657361123333214 -4.7594183250852895 24.988459626337075 1.067368053787491 1.466399280213692 0.5897286928162442 0.09963336309800098 39.13120326069306 483697.194093191 0.025740928108543382 0.16408373150833835 1.740129922088964e-05 4.7594183250852895 0.39903122642620104 AALDGGVASAAS(ph)PESKPSPGTK ddPTM_PC-9_AZD4547_30min_R2 4 AALDGGVASAASPESKPSPGTK 22 1 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 AALDGGVAS(0.367)AAS(0.566)PES(0.049)KPS(0.016)PGT(0.002)K;AALDGGVAS(0.003)AAS(0.795)PES(0.197)KPS(0.005)PGTK;AALDGGVAS(0.003)AAS(0.986)PES(0.011)KPSPGTK;AALDGGVAS(0.003)AAS(0.955)PES(0.037)KPS(0.005)PGTK 100.7 4.2653999999999995e-05 293748000.0 765111.0 607081.0 884100.0 1020939.0 1008308.0 923902.0 874985.0 928935.0 820072.0 958369.0 True False 1008400.382702564 803308.0611340033 872376.2563393216 785577.2869003136 868321.8388629892 866130.2618868208 952856.9699294545 785389.4405527092 863419.3317098301 924816.7930148209 1.0903785380186144 0.8686131860941778 0.9432962970919377 0.8494409842401338 0.9389122747569677 0.936542532995441 1.0303197099430095 0.8492378668778376 0.9336112170878293 1.0 19.818808069268528 -6.7503850768551095 4.379161587330808 0.9457887939372008 0.9293414524479577 0.0 0.07475707806992901 1.6303423690680479 73.98779586999187 0.02580953743132848 0.024370554822913913 1.7767033578996466e-07 6.7503850768551095 -0.016447341489243095 AALDGGVASAAS(ph)PESKPSPGTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AALDGGVASAASPESKPSPGTK 22 1 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 AALDGGVAS(0.008)AAS(0.749)PES(0.18)KPS(0.059)PGT(0.004)K;AALDGGVAS(0.005)AAS(0.932)PES(0.062)KPS(0.001)PGTK;AALDGGVAS(0.008)AAS(0.99)PES(0.002)KPSPGTK;AALDGGVAS(0.051)AAS(0.74)PES(0.199)KPS(0.008)PGT(0.002)K 104.26 2.1234e-05 219351000.0 790855.0 721445.0 784222.0 871674.0 998710.0 936492.0 1013381.0 970810.0 885774.0 698629.0 True False 924731.1314017483 793065.2917360979 802920.8266584986 822836.931785239 803019.9447997235 887380.7109200557 917386.2154369118 945327.2661582204 898726.76903023 825284.9073558771 1.1204992641444105 0.9609594028285245 0.9729013816949221 0.9970337812447326 0.9730214834202068 1.0752416565609164 1.1115994091981123 1.1454556574734245 1.0889897064877299 1.0 19.654532731337078 -6.886672164593807 5.0798052723059754 1.0979044278145995 1.000541191301304 0.33796949802598475 0.05448584892494525 0.20630070967586112 8.354850980106649 0.019061010475611023 0.01678992715832081 1.2981588409752796e-07 6.886672164593807 -0.09736323651329548 AALDGGVASAAS(ph)PESKPSPGTK ddPTM_PC-9_Lapatinib_30min_R1 4 AALDGGVASAASPESKPSPGTK 22 1 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 AALDGGVASAAS(0.995)PES(0.005)KPSPGTK;AALDGGVAS(0.001)AAS(0.855)PES(0.092)KPS(0.045)PGT(0.006)K;AALDGGVAS(0.005)AAS(0.992)PES(0.003)KPSPGTK;AALDGGVAS(0.003)AAS(0.99)PES(0.005)KPS(0.002)PGTK 131.26 6.2378e-06 315336000.0 958184.0 862527.0 900957.0 824700.0 973749.0 888003.0 782977.0 788549.0 948254.0 752207.0 True False 944520.1204505754 860529.8717249993 826883.7932545934 885351.1891185524 916474.9982841932 850025.1817260977 823515.7179241154 825187.865279656 841451.6489627009 882224.977697174 1.0706114022253226 0.9754086468637464 0.9372708936590814 1.003543553515724 1.038822320216347 0.9635016047095768 0.9334531879540474 0.9353485631676413 0.9537835248771787 1.0 19.750787081262004 -6.981900335161686 23.720977358026147 0.9500042227151481 0.9997759006897756 0.28185119631188416 0.03749628155704066 179.26569525422676 234939.49118032216 0.013586384870109634 0.011979151986587671 1.042556654903024e-07 6.981900335161686 0.04977167797462756 AALDGGVASAASPESKPS(ph)PGTK ddPTM_PC-9_AZD4547_30min_R2 2 AALDGGVASAASPESKPSPGTK 22 1 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 AALDGGVASAASPES(0.174)KPS(0.768)PGT(0.058)K;AALDGGVASAASPES(0.055)KPS(0.647)PGT(0.298)K 88.574 0.00010031 17645800.0 53322.0 53493.0 68800.0 82543.0 86072.0 81573.0 72644.0 85121.0 70445.0 86907.0 True False 70277.28683350018 70783.56613737077 67887.6670468786 63513.98662663734 74122.38851086673 76472.2274146974 79109.17526992489 71967.50533598944 74168.5788836822 83864.41238243197 0.8379869939710204 0.844023872898424 0.8094931463575104 0.7573413420820956 0.8838360206097859 0.9118555206226772 0.9432985103285215 0.8581411744448744 0.8843867950265295 1.0 16.355771116659454 -6.459562813999152 6.124573479688463 0.9108141572892933 0.8143868386350691 0.5951757308494503 0.041490684580887394 0.175545904857857 13.08181572985323 0.013130480529418346 0.014758007086670384 3.470860716096239e-07 6.459562813999152 -0.09642731865422416 AALDGGVASAASPESKPS(ph)PGTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AALDGGVASAASPESKPSPGTK 22 1 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 AALDGGVASAASPES(0.256)KPS(0.737)PGT(0.007)K;AALDGGVASAAS(0.001)PES(0.084)KPS(0.787)PGT(0.128)K 97.62100000000001 6.3008e-05 21602200.0 66738.0 66231.0 72329.0 94136.0 94805.0 102824.0 79734.0 96079.0 80300.0 65127.0 True False 78035.42526441623 72805.97597456958 74053.59766926015 88861.86511302998 76228.64081338678 97431.72842869324 72181.01829582994 93557.0280541155 81474.23558732521 76934.00955495163 1.0143163695202693 0.9463431893870874 0.9625599666213408 1.1550400873044144 0.9908315094241771 1.2664324788519012 0.9382198940804357 1.216068531918781 1.0590145510241558 1.0 16.231333878513016 -5.746211707865071 24.799584342869515 1.095348897925547 0.9716001154551894 0.22260584691387142 0.09796693022815135 290.0606008588541 472384.68648915127 0.024449272880876647 0.04213844954911439 1.7938589515948686e-06 5.746211707865071 -0.12374878247035759 AALDGGVASAASPESKPS(ph)PGTK ddPTM_PC-9_Lapatinib_30min_R1 2 AALDGGVASAASPESKPSPGTK 22 1 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 AALDGGVASAAS(0.003)PES(0.284)KPS(0.576)PGT(0.137)K;AALDGGVASAASPES(0.236)KPS(0.709)PGT(0.055)K 112.34 3.7898e-06 20475100.0 79881.0 72987.0 78366.0 89985.0 91396.0 81303.0 67045.0 65021.0 83627.0 55901.0 True False 78741.88229161868 72818.00308580804 71923.04998150795 96602.79708116043 86020.26697144947 77825.86021654986 70516.2620462955 68042.11303083062 74208.04662864983 65563.41336659955 1.2010033988214033 1.110649969955717 1.0969997791199237 1.4734253773671506 1.3120162992500846 1.1870318554249841 1.0755428740721897 1.0378061412143287 1.1318514826815618 1.0 16.000603345623112 -7.184508891779221 3.472480052252601 1.062697584459658 1.237484377924201 0.3940886802282727 0.10401173225871482 0.2994114436107207 7.0011512191778875 0.04763554807290634 0.03511471947357172 6.538695424914927e-08 7.184508891779221 0.17478679346454307 AALEDS(ph)SGSSELQEIMR ddPTM_PC-9_AZD4547_30min_R2 1 AALEDSSGSSELQEIMR 17 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 AALEDS(0.81)S(0.042)GS(0.031)S(0.117)ELQEIMR 108.14 0.0038819 0.0 10621.0 10334.0 13988.0 19535.0 16476.0 16614.0 12994.0 17500.0 14411.0 14659.0 True False 13998.257069476118 13674.263407615763 13802.50998040316 15031.507562741363 14188.591796461584 15575.123953609407 14150.440827286531 14795.777109994166 15172.736039360394 14145.792871852344 0.98957034054487 0.9666664521028834 0.9757325096897003 1.0626132942078796 1.0030255585527768 1.1010428397125185 1.0003285751089595 1.0459489435502183 1.0725970736890604 1.0 13.788085421623439 -5.750405736299337 24.918936149297142 1.041958948221647 0.9762574070377206 0.45418652187141784 0.03186074557492155 173.01693744061967 390745.98119383404 0.008157417144151063 0.013958155239915285 1.7766188419031812e-06 5.750405736299337 -0.06570154118392635 AALEEVER ddPTM_PC-9_AZD4547_30min_R2 1 AALEEVER 8 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 94.11399999999999 0.031481 2069400.0 12139.0 10655.0 15049.0 19717.0 19013.0 13924.0 14007.0 14756.0 12832.0 14402.0 False True 15998.949493114631 14099.020380118618 14849.440427158073 15171.55027461334 16373.373138269257 13053.330078852627 15253.595864845502 12475.799259147081 13510.273322952786 13897.790363627633 1.1511865609216563 1.0144792813264496 1.0684749185756202 1.091651973274781 1.1781277965683346 0.9392378023642469 1.0975554721825558 0.8976822165772415 0.9721166436868244 1.0 13.762567903876443 -7.242015157946897 1.3919266661871883 0.9626527858723563 1.0881388752252412 0.35294282311879754 0.06988965041669815 0.47297637610923476 1.7920979001676598 0.04081461391398979 0.024302150724047435 5.7277603934268124e-08 7.242015157946897 0.12548608935288497 AALEEVER ddPTM_PC-9_Lapatinib_30min_R1 1 AALEEVER 8 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 90.37 0.043891 1528800.0 14102.0 15757.0 20839.0 14580.0 16280.0 17276.0 15513.0 15172.0 14546.0 13015.0 False True 13900.902894009922 15720.515634607193 19125.697860866247 15652.261837454209 15322.442407711482 16537.145752322966 16316.187234308043 15876.946508109102 12907.676303829394 15264.625408602595 0.9106612525306957 1.0298657984589439 1.2529424960593982 1.0253944278667433 1.0037876461138904 1.0833640072820407 1.0688888064762354 1.04011373244452 0.8455940423244904 1.0 13.897904566029467 -8.127489071897925 6.679613709191281 0.9241969346366895 1.0581385729690018 0.2562476726621774 0.08789238123629381 0.3213642844052945 15.770870482554091 0.06127509246935442 0.022787285017686412 7.456086334559836e-09 8.127489071897925 0.13394163833231232 AALEQPCEGS(ph)LTRPK ddPTM_PC-9_Lapatinib_30min_R1 1 AALEQPCEGSLTRPK 15 1 D6RGY3;D6R960;Q6PUV4 D6RGY3 CPLX2 Complexin-2 1 AALEQPCEGS(0.823)LT(0.177)RPK 63.578 0.018234999999999998 9980500.0 42425.0 29534.0 30225.0 27543.0 24155.0 22311.0 25738.0 27578.0 28212.0 26506.0 True False 41820.01172020785 29465.615837563542 27740.01717187402 29568.60410075454 22734.250390557194 21356.810539481245 27070.587702998808 28859.374558438758 25034.467474469624 31087.526782975056 1.3452344412007193 0.9478275979709089 0.8923198479418992 0.9511404463653781 0.731298136042379 0.6869896948887296 0.8707861481545677 0.9283264879804933 0.8052897758396026 1.0 14.924048224923634 AALEQPCEGSLT(ph)RPK ddPTM_PC-9_Lapatinib_30min_R1 1 AALEQPCEGSLTRPK 15 1 D6RGY3;D6R960;Q6PUV4 D6RGY3 CPLX2 Complexin-2 1 AALEQPCEGS(0.429)LT(0.571)RPK 72.184 0.014530000000000001 12931000.0 59077.0 46478.0 49475.0 41785.0 38114.0 30810.0 28959.0 28992.0 36203.0 39328.0 True False 58234.551146605016 46370.383046599825 45407.35647902288 44858.0082906738 35872.20945500711 29492.328121617913 30458.355322524763 30339.074160499516 32125.436905509112 46125.792398734004 1.262516004997745 1.005302687176655 0.9844244210809299 0.9725146378602919 0.7777039176890472 0.6393890833716578 0.6603324027309445 0.6577464057036388 0.6964744719787371 1.0 15.493286075110655 -5.731999813263497 0.9114422923953632 0.7017307744746158 1.194257604867252 0.6619673609498578 0.11533409644615812 0.42924825464519434 0.6459647375229127 0.047017798568938014 0.15819458886663398 1.8535324203903731e-06 5.731999813263497 0.4925268303926361 AALEQPCEGSLTRPK ddPTM_PC-9_Lapatinib_30min_R1 2 AALEQPCEGSLTRPK 15 1 D6RGY3;D6R960;Q6PUV4 D6RGY3 CPLX2 Complexin-2 0 ; 139.64 8.1825e-05 12189000.0 43555.0 54225.0 50133.0 44011.0 51753.0 43119.0 45523.0 34630.0 39991.0 48940.0 False True 42933.89771299122 54099.44534407406 46011.25825897632 47247.715756392136 48708.9902903128 41274.900885298346 47879.958194250314 36239.03622303047 35486.79245610073 57399.21379154908 0.7479875572670718 0.942511957403137 0.80160084467482 0.8231422111107111 0.8486003043038937 0.7190847776276558 0.8341570385986664 0.6313507420961567 0.6182452704835736 1.0 15.808743355704745 -6.757359852965562 24.996024936640158 0.742126324578384 0.8365991020095768 0.08340060181377229 0.11123699176873895 205.93769236281477 1261817.9193357863 0.03614238688297702 0.034890446679336294 1.748397380053162e-07 6.757359852965562 0.09447277743119276 AALKEWNGVVS(ph)ESDSPVK ddPTM_PC-9_Lapatinib_30min_R1 1 AALKEWNGVVSESDSPVK 18 1 M0R0Q7;P18858-2;P18858;B4E135;F5GZ28;M0QY71;M0R1G7 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 AALKEWNGVVS(0.379)ES(0.379)DS(0.242)PVK 74.324 0.0029912 6115400.0 39789.0 26976.0 27921.0 35046.0 32630.0 24546.0 22238.0 21126.0 27959.0 21161.0 True False 39221.60156359103 26913.53872940051 25625.443158176797 37623.39975002881 30710.76755304826 23496.224799520714 23389.37482863033 22107.59108425474 24809.962998677725 24818.650654739882 1.5803277184249525 1.0844078150663095 1.032507508754624 1.5159325248346436 1.2374068187781633 0.9467164483026957 0.9424112194497332 0.8907652310272806 0.9996499545368919 1.0 14.599137060423304 -6.734371631004642 5.270953171158856 0.946924470225499 1.2800054984318336 0.5233103392264467 0.15958835042162717 0.15867599667731072 11.61369608782511 0.05529432633441835 0.05333844671352104 1.843437292631315e-07 6.734371631004642 0.3330810282063347 AALKEWNGVVSESDS(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AALKEWNGVVSESDSPVK 18 1 M0R0Q7;P18858-2;P18858;B4E135;F5GZ28;M0QY71;M0R1G7 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 AALKEWNGVVS(0.004)ES(0.12)DS(0.876)PVK;AALKEWNGVVS(0.002)ES(0.317)DS(0.681)PVK 97.04899999999999 0.00037591 5317200.0 38272.0 21778.3 29025.0 52439.0 52285.0 50196.0 49760.0 50601.0 49526.0 36887.0 True False 44750.693693543915 23940.305696229447 29717.06607792548 49501.012839531846 42040.12958101297 47563.63339499222 45046.372568797546 49272.77736619124 50250.224056013234 43574.32110266865 1.0269969229836886 0.5494131656078345 0.6819857504585539 1.136013403924272 0.9647913844018163 1.091551909275283 1.033782545060438 1.1307755604521306 1.1532072740184522 1.0 15.411190566575266 -5.7601562541110525 24.999987758017426 1.0729695021822903 0.7324600114317641 0.5790983595943329 0.12468681783096543 21.844773323734593 425596.55693884846 0.03338024990743248 0.0539771121670527 1.7371757006562282e-06 5.7601562541110525 -0.34050949075052617 AALPSLTNPPS(ph)LSPIR ddPTM_PC-9_Lapatinib_30min_R1 1 AALPSLTNPPSLSPIR 16 0 P42858 P42858 HTT Huntingtin 1 AALPSLT(0.001)NPPS(0.767)LS(0.232)PIR 89.23200000000001 0.020275 0.0 9670.8 11777.0 8955.2 8388.0 8597.7 8083.7 6521.4 7970.3 8782.4 4553.2 True False 9532.892618592483 11749.731080076726 8218.93802407167 9004.881501547723 8092.000189728565 7737.97899502508 6859.04618254473 8340.629235010672 7793.233629228052 5340.21455324236 1.7851141604047538 2.200235770104549 1.5390651334563825 1.6862396466974023 1.5152949584797923 1.4490015181743765 1.2844139714162228 1.5618528341612385 1.45934841222743 1.0 12.382681990747313 -1.5228787452843844 0.12848226635473028 0.9238713754106832 4.454737669965208 0.6763920889120193 0.16966382939135632 49.814801100845706 0.4358249719216503 0.9497083258441024 31.786600526179605 0.029999999999720455 1.5228787452843844 3.5308662945545253 AALPSLTNPPS(ph)LSPIRR ddPTM_PC-9_Lapatinib_30min_R1 1 AALPSLTNPPSLSPIRR 17 1 P42858 P42858 HTT Huntingtin 1 AALPSLTNPPS(0.881)LS(0.119)PIRR 153.04 1.317e-05 3591100.0 36203.0 30999.0 26057.0 22868.0 27077.0 23181.0 19555.0 16691.0 24119.0 14955.0 True False 35686.73858118289 30927.223720072874 23914.69404292873 24549.789005411723 25484.38409543023 22189.60266755029 20567.46221665015 17466.524793491215 21402.464235670373 17539.951823715077 2.034597297635234 1.763244507790346 1.3634412615999674 1.39964973975692 1.4529335286413843 1.265089145658234 1.172606539821945 0.995813726801428 1.2202122588918942 1.0 14.098357164744707 -1.5228787452803378 0.309498140438691 1.0485289015430144 10.022241436231901 0.9012242811011466 0.09704001187568 16.68935506025583 0.2382710161654499 0.10143081380295224 83.80616926099067 0.02999999999999998 1.5228787452803378 8.973712534688888 up AALPSLTNPPSLS(ph)PIR ddPTM_PC-9_AZD4547_30min_R2 2 AALPSLTNPPSLSPIR 16 0 P42858 P42858 HTT Huntingtin 1 AALPSLTNPPS(0.024)LS(0.976)PIR;AALPSLT(0.003)NPPS(0.105)LS(0.892)PIR 131.84 8.762999999999999e-06 15351300.0 21016.9 19560.3 26032.0 40833.0 28953.0 33135.0 24805.0 30766.0 20518.8 25620.0 True False 27699.8370213231 25882.78445248563 25686.798670993358 31419.582713561198 24933.375715158567 31063.063211920537 27012.596946347734 26011.82163234744 21603.381878039567 24723.051598121074 1.1204052586869275 1.0469089687315418 1.038981719916223 1.2708618347076965 1.0085072069765642 1.256441304935079 1.0926077162901955 1.052128275067966 0.8738153456623211 1.0 14.593569207490773 -8.017618450683345 3.3296647870345426 0.9382813197916461 1.119526129012197 0.4081792838611332 0.08661847630240428 0.23610904211333916 5.27317995948003 0.06092137206704797 0.02236698268915179 9.602438830839065e-09 8.017618450683345 0.18124480922055086 AALPSLTNPPSLS(ph)PIRR ddPTM_PC-9_AZD4547_30min_R2 1 AALPSLTNPPSLSPIRR 17 1 P42858 P42858 HTT Huntingtin 1 AALPSLTNPPS(0.031)LS(0.969)PIRR 105.95 0.00031578 3627800.0 12439.0 11104.0 15799.0 25152.0 17260.0 16362.0 10899.0 19806.0 15354.0 13335.0 True False 16394.343252726987 14693.150849445066 15589.494937116779 19353.59499452628 14863.74692928666 15338.881553446327 11868.98988583931 16745.43779660253 16165.581094187752 12868.145708858108 1.274025304317275 1.141823474949516 1.2114795161501288 1.5039925279369313 1.155080713692481 1.192004030766253 0.9223543278398686 1.3013093086966985 1.256247905481811 1.0 13.651516556700054 -6.4819124807639525 24.992046975142877 1.1436939684322116 1.2753961755581866 0.21451797906465953 0.13552461648259054 928.0485256250853 566169.4583104008 0.043218842504920744 0.04899945818589779 3.296761419808537e-07 6.4819124807639525 0.13170220712597502 AALPSLTNPPSLS(ph)PIRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AALPSLTNPPSLSPIRR 17 1 P42858 P42858 HTT Huntingtin 1 AALPSLTNPPS(0.226)LS(0.774)PIRR 92.56299999999999 0.00092827 2641800.0 18410.0 15157.0 20828.0 19837.0 21240.0 17727.0 14621.0 14324.0 12418.0 12480.0 True False 21526.44938592558 16661.686790876687 21324.61851062986 18725.597202421726 17078.174472615774 16797.364913400026 13235.993033126786 13948.010177532526 12599.589757452088 14742.525208374354 1.4601602562427827 1.1301786196988945 1.4464698692539193 1.2701756949877776 1.1584293892144526 1.139381800334887 0.8978104392596327 0.9461072631986742 0.8546425784841126 1.0 13.847696040588408 -6.83323022736602 1.2081878931293328 0.9098803067634373 1.3262035543249473 0.7658604689916519 0.09799651513370114 0.20920570304784417 0.641009941166235 0.04873486874559081 0.04105357116084317 1.4681477796012423e-07 6.83323022736602 0.41632324756150996 AALQELLSK ddPTM_PC-9_Lapatinib_30min_R1 2 AALQELLSK 9 0 P62851 P62851 RPS25 40S ribosomal protein S25 0 ; 125.48 0.0065666 15613300.0 94960.0 84731.0 92469.0 91693.0 98184.0 92554.0 84725.0 77960.0 82836.0 78580.0 False True 93605.85298646856 84534.81057535727 84866.55576066245 98436.40909888137 92409.01015717095 88595.68117391178 89111.64593739106 81582.3062069723 73506.1373782492 92162.4482987318 1.0156615271662288 0.917237032390344 0.9208366024042598 1.0680750231353815 1.0026752963163474 0.9612991278914506 0.9668975551576929 0.8852011606997956 0.7975714484058545 1.0 16.491891422084045 -7.740384192761681 4.555514919376 0.8796777329173168 0.9788537476187972 0.2743752593808516 0.06211549840338454 0.23013802361637054 11.394470666322679 0.032685599193308955 0.016904467214914225 1.8180917965867308e-08 7.740384192761681 0.09917601470148041 AALQTAPES(ph)ADDSPSQLSK ddPTM_PC-9_AZD4547_30min_R2 1 AALQTAPESADDSPSQLSK 19 0 O43524;O43524-2 O43524 FOXO3 Forkhead box protein O3 1 AALQT(0.001)APES(0.534)ADDS(0.449)PS(0.015)QLSK 282.72 7.613699999999999e-106 8704500.0 30054.0 26968.0 28064.0 37538.0 38217.0 36572.0 26140.0 36535.0 29541.0 35712.0 True False 39610.54683796582 35684.8786120168 27691.85302330813 28884.194056318673 32911.22922343847 34285.14705858935 28466.409360110072 30889.35524077924 31102.476950853204 34461.73374988681 1.1494066759800188 1.035492841741719 0.8035536814336594 0.8381526671278848 0.9550079361154188 0.9948758616563208 0.8260295191968853 0.8963378182004758 0.9025221184919451 1.0 15.072707664090952 -5.021397101645683 4.415991950340799 0.8987687728018293 1.131980170665329 0.6062340798361633 0.06433015207006783 0.12097151277657325 5.807067524407542 0.01692561389249038 0.06009773461344391 9.51925363182469e-06 5.021397101645683 0.23321139786349965 AALQTAPESADDS(ph)PSQLSK ddPTM_PC-9_AZD4547_30min_R2 1 AALQTAPESADDSPSQLSK 19 0 O43524;O43524-2 O43524 FOXO3 Forkhead box protein O3 1 AALQTAPES(0.019)ADDS(0.963)PS(0.018)QLS(0.001)K 168.05 6.7816e-08 7355000.0 28817.0 34770.0 42069.0 59660.0 44302.0 51378.0 40192.0 47247.0 42226.0 49520.0 True False 37980.206569164235 46008.722535591216 41511.13757260371 45906.30873781163 38151.4320081841 48165.32553801277 43769.01013777904 39946.061778051066 44457.98015391243 47786.31987271493 0.7947924567183547 0.9628011250529739 0.8686824531199309 0.9606579636199032 0.7983756043529905 1.007931258701389 0.9159318033772738 0.8359309083531142 0.9303495283238391 1.0 15.544310046363393 -14.5228787452803 0.3041989487534219 1.854404235590057 0.8944569833301416 0.17496314671085733 0.0681901759764834 508.6535052937454 4.6636901974508715 277.8339074778581 0.06296426170052272 3.000000000000259e-15 14.5228787452803 -0.9599472522599154 AALQTAPESADDS(ph)PSQLSK ddPTM_PC-9_Lapatinib_30min_R1 4 AALQTAPESADDSPSQLSK 19 0 O43524;O43524-2 O43524 FOXO3 Forkhead box protein O3 1 AALQTAPES(0.004)ADDS(0.519)PS(0.432)QLS(0.045)K;AALQTAPESADDS(0.992)PS(0.007)QLS(0.001)K;AALQTAPES(0.297)ADDS(0.395)PS(0.297)QLS(0.01)K;AALQTAPES(0.092)ADDS(0.835)PS(0.073)QLSK 273.8 1.01e-91 33908800.0 153306.0 149751.0 173619.0 140896.0 150314.0 147898.0 138240.0 130896.0 140577.0 112208.0 True False 151119.82832712287 149404.260760174 159344.716008721 151257.96185527786 141472.8260486943 141572.74730707717 145397.3907864852 136977.9060193416 124743.73791856339 131603.00329223808 1.148300757176078 1.1352648269614818 1.210798477409209 1.149350380092724 1.0749969416316378 1.075756204383119 1.1048181815700304 1.040841793824173 0.9478791121624863 1.0 17.005832887411017 -7.310359626390718 0.6340451517948588 0.977284588704924 1.165263723940939 0.7680506500543083 0.035688225331981155 0.38966670858906305 0.31513780384030876 0.034090127830950674 0.023399664545355768 4.8937341591653655e-08 7.310359626390718 0.18797913523601495 AALS(ph)LPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AALSLPAK 8 0 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 AALS(1)LPAK 73.985 0.028458999999999998 1354400.0 15638.0 12080.0 10959.0 13578.0 14900.0 11284.0 14440.0 13105.0 9299.7 7867.9 True False 18285.204535421184 13279.222566061253 11220.304122238935 12817.26868046994 11980.451960544955 10692.247175653287 13072.138663453312 12761.007635895267 9435.690519196105 9294.287987737865 1.9673593673388654 1.4287509256847635 1.2072257861002478 1.3790479375483105 1.2890123456848979 1.1504105736512336 1.4064701546476328 1.372994644961627 1.0152139175851658 1.0 13.182128632764899 -4.750544435088765 2.4302792907326674 1.2518713355418032 2.168148975814673 0.7231992258042331 0.13743475519408635 0.3188195514972263 2.177908464746962 0.03448545389250968 0.6409803266502279 1.7760515412607307e-05 4.750544435088765 0.9162776402728698 AALS(ph)LPAK ddPTM_PC-9_Lapatinib_30min_R1 1 AALSLPAK 8 0 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 AALS(1)LPAK 74.173 0.028161000000000002 2488200.0 50062.0 44251.0 37338.0 29454.0 35043.0 35871.0 40386.0 37291.0 40849.0 29219.0 True False 49348.106699753545 44148.53952827334 34268.21376884804 31620.145415663654 32981.839637188794 34336.88094938513 42476.98946978437 39023.67599748852 36248.155460960195 34269.4652181298 1.4400022406432706 1.2882762904895622 0.9999634820889737 0.9226915335385928 0.9624264466123094 1.001967224490555 1.23949963033892 1.1387302296402213 1.0577391631365054 1.0 15.06463605803706 -5.077320705803443 3.3219983864454226 1.044542415342576 1.422617841727489 0.6992160995532977 0.08732309838661145 0.1536062771413077 3.157604894706494 0.026386173620073138 0.09929714956229946 8.369110349177098e-06 5.077320705803443 0.3780754263849131 AALSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 AALSSPR 7 0 Q68E01-4;Q68E01-3;Q68E01-2;Q68E01 Q68E01-4 INTS3 Integrator complex subunit 3 1 AALS(0.079)S(0.921)PR;AALS(0.223)S(0.777)PR 93.598 0.018553999999999998 75087700.0 73210.0 73609.0 96386.0 126361.0 98336.0 85089.0 88523.0 111666.0 82518.0 100179.0 True False 96489.25713740214 97401.66974755055 95107.85866250649 97230.42370798887 84683.74380291614 79768.37137887743 96401.37550822562 94410.58552940631 86879.73301616413 96671.76370211465 0.9981121005997687 1.0075503540794502 0.9838225250091931 1.0057789367285743 0.8759925397023012 0.8251465404590786 0.9972030282314679 0.9766097349824302 0.8987084717299274 1.0 16.5608069423066 -6.237450752152066 24.456549377140423 0.9259970102446297 0.9983689144475953 0.30265914908775027 0.051841285817192995 794.7308725623403 810232.5361681721 0.01618823278865721 0.020887032692649975 5.788276221522456e-07 6.237450752152066 0.07237190420296569 AALSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AALSSPR 7 0 Q68E01-4;Q68E01-3;Q68E01-2;Q68E01 Q68E01-4 INTS3 Integrator complex subunit 3 1 AALS(0.024)S(0.976)PR;AALS(0.014)S(0.986)PR 84.916 0.019635 8498500.0 75472.0 72399.0 99236.0 92946.0 109879.0 106026.0 98456.0 94204.0 99518.0 79159.0 True False 88247.9189600531 79586.29425167789 101602.16259462587 87738.53695499786 88348.99872300122 100465.80991189438 89129.53492028794 91731.24481738875 100973.26248044112 93509.90007770067 0.9437280853334757 0.8511001956535814 1.0865390991777453 0.9382807262342577 0.9448090378621827 1.0743868812651258 0.95315613476463 0.9809789630955228 1.0798136068645017 1.0 16.512831493607507 -5.248299942115662 24.995568803687863 1.0023394695069956 0.8974141409537554 0.3676425209691606 0.05732943266488633 828.1969027625997 1575498.7863824687 0.01412127606662642 0.0368332056010917 5.645469401748408e-06 5.248299942115662 -0.10492532855324022 AALSS(ph)SELLELGDSLMR ddPTM_PC-9_AZD4547_30min_R2 1 AALSSSELLELGDSLMR 17 0 Q9P2G1 Q9P2G1 ANKIB1 Ankyrin repeat and IBR domain-containing protein 1 1 AALS(0.29)S(0.594)S(0.116)ELLELGDSLMR 122.12 5.5163999999999996e-05 3616500.0 5114.9 6649.4 8981.8 13933.0 14447.0 10695.0 10647.0 12713.0 10833.0 11767.0 True False 6741.331803470799 8798.688513895893 8862.695463396136 10720.962112704143 12441.283423372219 10026.239959302557 11594.562374027997 10748.497965677474 11405.610263992177 11355.04091159605 0.5936862628637809 0.7748707012504423 0.7805075765376883 0.9441588274469033 1.0956616995247346 0.8829770000267908 1.021093844073018 0.9465838167699459 1.0044534716158076 1.0 13.471045283555537 -5.310087852984563 1.1458835307303914 0.9896851612541683 0.5902133402367329 0.8106339621221675 0.06182333623504873 0.3216995983587518 0.6245597735224416 0.020229330108993616 0.12435412142495941 4.896797525346619e-06 5.310087852984563 -0.3994718210174354 AAMYDIIS(ph)SPSK ddPTM_PC-9_Lapatinib_30min_R1 1 AAMYDIISSPSK 12 0 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 AAMY(0.154)DIIS(0.394)S(0.394)PS(0.058)K 62.338 0.045868 3439100.0 26919.0 41625.0 35929.0 35322.0 41491.0 38858.0 40560.0 44911.0 36686.0 33055.0 True False 26535.130123659983 41528.61986993235 32975.05630995074 37919.69771073784 39050.58095444455 37196.1339224222 42659.99833839582 46997.729015666206 32554.03635929366 38768.51270698107 0.6844505571884316 1.0711945589404637 0.8505628410143499 0.9781055568817222 1.0072757046316272 0.9594418595202976 1.1003774805814 1.21226546323515 0.8397029982899404 1.0 15.242597768973837 -4.75418022489919 24.999222432549796 1.0051502631019709 0.6844499964143996 0.4509899333285794 0.1050945259796632 242.19993316835198 834022.0872196115 0.026293766275233645 0.2630364587940006 1.7612450077078827e-05 4.75418022489919 -0.32070026668757123 AAMYDIIS(ph)SPSKDSTK ddPTM_PC-9_AZD4547_30min_R2 2 AAMYDIISSPSKDSTK 16 1 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 AAMY(0.002)DIIS(0.496)S(0.496)PS(0.005)KDSTK;AAMY(0.086)DIIS(0.768)S(0.146)PSKDSTK 83.25200000000001 0.008641 107692000.0 340237.0 261565.0 343496.0 376241.0 361917.0 308188.0 327316.0 340973.0 324318.0 351174.0 True False 448425.288630763 346110.7710676426 338941.0186037003 289504.4503155039 311671.07169215713 288916.95564072364 356446.4899048893 288283.4576300597 341460.78737168066 338879.50514904584 1.3232588038439703 1.0213387525911792 1.0001815201383375 0.8542990824664188 0.9197105961160976 0.8525654436188235 1.0518384395896623 0.8506960534638026 1.0076171092775277 1.0 18.37041286217662 -4.472354667841711 1.4987767265924319 0.9310808283036909 1.792416823413357 0.7323447185835776 0.0690229789986145 1.2045541168621832 1.3915242348875572 0.01838132380691652 1.9267288642467715 3.370119744466232e-05 4.472354667841711 0.8613359951096662 AAMYDIIS(ph)SPSKDSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AAMYDIISSPSKDSTK 16 1 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 AAMY(0.006)DIIS(0.483)S(0.483)PS(0.026)KDS(0.002)T(0.001)K;AAMYDIIS(0.586)S(0.338)PS(0.065)KDS(0.007)T(0.004)K;AAMY(0.001)DIIS(0.549)S(0.375)PS(0.074)KDS(0.001)T(0.001)K 107.35 0.0019912 38823000.0 346459.0 330044.0 291682.0 421681.0 422915.0 420490.0 440804.0 479344.0 390934.0 335118.0 True False 405107.66582283395 362808.5871351912 298636.80509014433 398055.58067824825 340047.8416707299 398438.76416966063 399047.85397540673 466761.72790695075 396650.67017553345 395872.2406073715 1.0233293074586207 0.9164789796287509 0.7543767267741669 1.0055152643881444 0.8589838003013488 1.0064832117512241 1.0080218137123305 1.179071629753115 1.0019663656309108 1.0 18.594675380546455 -7.063831272188916 2.2500149339225657 1.0653671544567906 0.9085269542802588 0.34850496091550365 0.0861437227327746 0.3188073977490349 3.1962096373439346 0.03732788152139037 0.028126782100740214 8.63313888823085e-08 7.063831272188916 -0.15684020017653189 AAMYDIIS(ph)SPSKDSTK ddPTM_PC-9_Lapatinib_30min_R1 2 AAMYDIISSPSKDSTK 16 1 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 AAMY(0.038)DIIS(0.552)S(0.406)PS(0.003)KDSTK;AAMYDIIS(0.445)S(0.445)PS(0.109)KDS(0.001)TK 102.57 0.00069962 112890000.0 538650.0 425290.0 435900.0 450700.0 454420.0 434450.0 383260.0 403700.0 454890.0 356070.0 True False 530968.752223687 424305.2671347388 400061.9846226601 483845.98149112536 427691.9090240946 415869.5862524148 403103.32749441714 422457.37577930675 403655.4979959406 417616.2250665493 1.271427498151142 1.0160171987262314 0.9579656167786779 1.1585899983029204 1.0241266582876172 0.9958175982892997 0.9652482430015273 1.0115923434535763 0.9665704389996246 1.0 18.67181823847183 -4.7616510677515 7.990949642693162 1.0123312321923381 1.2746266081222255 0.6767795690742986 0.05405809526106822 0.05686097074681781 32.06720951433375 0.013878022045453041 0.08088404671268046 1.731206732055081e-05 4.7616510677515 0.2622953759298874 AAMYDIISS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 1 AAMYDIISSPSK 12 0 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 AAMYDIIS(0.002)S(0.998)PSK 145.28 0.00010795 4744000.0 37155.0 53401.0 56709.0 40483.0 42005.0 53276.0 65368.0 63929.0 59010.0 54459.0 True False 48969.51712799031 70661.82893652881 55957.00160699761 31150.26980611511 36173.330809078 49944.64329797129 71185.62536540451 54050.241992275216 62129.148128697314 52552.406986029535 0.931822535569271 1.3445973836234268 1.0647847513791928 0.5927467758878496 0.6883287157274123 0.9503778449434012 1.3545645089924885 1.0285017393521836 1.1822322076553724 1.0 15.681469223038196 -7.037366736165562 23.848294272455945 1.1449529470959854 0.9253837927791748 0.1977321302025976 0.21022740183427582 617.2998994540247 393972.3980207273 0.08934196773597916 0.06923010060977373 9.175574459088136e-08 7.037366736165562 -0.21956915431681057 AAMYDIISS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AAMYDIISSPSK 12 0 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 AAMYDIIS(0.102)S(0.893)PS(0.005)K;AAMY(0.021)DIIS(0.177)S(0.782)PS(0.019)K;AAMYDIIS(0.171)S(0.705)PS(0.124)K;AAMYDIIS(0.26)S(0.738)PS(0.002)K 112.84 0.00079677 36761800.0 204796.0 317606.0 220864.0 216702.0 227182.0 165556.0 216468.0 176167.0 161115.0 161274.0 True False 239463.9178946228 349135.82469507074 226130.2353913844 204560.88949736327 182667.3179396324 156873.95191531867 195962.58394739666 171542.8029143652 163471.0020753661 190511.6995557186 1.2569512447427789 1.8326214374721885 1.186962459096894 1.0737444995473138 0.9588246725299305 0.8234347406545394 1.0286118091665224 0.9004318543921991 0.8580627985398662 1.0 17.539520072537186 -5.590669067432453 2.5286040819336946 0.9362590153314869 1.5454449194956685 0.7051873670541249 0.15153047928522242 0.133774954324484 1.7161253645295385 0.04053394920615563 0.08636098181098664 2.5664389190872405e-06 5.590669067432453 0.6091859041641816 AAMYDIISS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 1 AAMYDIISSPSK 12 0 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 AAMYDIIS(0.028)S(0.971)PS(0.001)K 87.21600000000001 0.030314999999999998 0.0 30158.0 49233.0 43409.0 42139.0 43988.0 43204.0 46391.0 47364.0 37861.0 37597.0 True False 29727.941389700125 49119.004013366524 39840.07958358572 45238.04263158318 41400.712323735446 41356.26563344304 48792.89898709369 49564.70435078297 33596.69548599509 44095.591355146506 0.6741703756793025 1.1139209726832187 0.9034934867459462 1.02590851469108 0.9388855223710129 0.9378775601478866 1.1065255615717908 1.1240285667469148 0.7619059968015134 1.0 15.42834680295113 -4.747549855374683 24.980707738396728 0.9929486737680125 0.6741695709953073 0.44257828595757176 0.10639109749271224 655.5358446468956 1178931.7208061947 0.025415025072871175 0.513550789637069 1.7883402225858318e-05 4.747549855374683 -0.31877910277270527 AAMYDIISS(ph)PSKDSTK ddPTM_PC-9_AZD4547_30min_R2 2 AAMYDIISSPSKDSTK 16 1 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 AAMYDIIS(0.195)S(0.784)PS(0.02)KDSTK;AAMYDIIS(0.19)S(0.62)PS(0.19)KDSTK 105.2 0.00054626 125239000.0 250860.0 209819.0 281050.0 310620.0 294300.0 261290.0 308440.0 253090.0 266200.0 323710.0 True False 330628.2617878528 277638.8885158248 277323.09336519253 239011.35803116078 253441.5249877791 244951.4949944987 335890.5624725455 213980.7559296244 280270.788541929 312377.011429655 1.058426995874848 0.8887942401560078 0.88778329780405 0.7651374758253757 0.8113321906367372 0.784153398079551 1.0752729880322374 0.6850080130746474 0.8972196361672532 1.0 18.252928760449457 -4.6203831332476115 1.9623887326651799 0.8513423544240022 1.1927119783213322 0.2191569668606772 0.10809395183158026 1.8907462786875353 5.422644875241705 0.027703998952287128 1.355690335658199 2.3967176092407853e-05 4.6203831332476115 0.34136962389733005 AAMYDIISS(ph)PSKDSTK ddPTM_PC-9_Lapatinib_30min_R1 3 AAMYDIISSPSKDSTK 16 1 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 AAMYDIIS(0.22)S(0.78)PS(0.001)KDSTK;AAMYDIIS(0.147)S(0.85)PS(0.003)KDSTK;AAMYDIIS(0.4)S(0.574)PS(0.026)KDSTK 125.33 0.00015512 81279000.0 463668.0 391369.0 378966.0 369766.0 378917.0 353551.0 347332.0 331491.0 382643.0 286488.0 True False 457056.0092937018 390462.8091261402 347808.87833106425 396959.8251432154 356629.84703948506 338430.447897635 365315.15145147167 346893.28202739265 339545.7159305783 336007.06907873583 1.3602571235981966 1.162067245182404 1.0351236933338535 1.1814031955684738 1.061376024073817 1.007212285222283 1.0872246005213304 1.0323987616644632 1.0105314654883444 1.0 18.358132059874045 -1.5228787455460249 0.7206448870053328 1.0425961885272006 46.11589397772447 0.7911847803507067 0.04897637912616727 144.46293576901823 0.7048608571394736 0.01912636479189934 10526.849088071225 0.02999999998164697 1.5228787455460249 45.07329778919727 AAMYDIISSPS(ph)KDSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAMYDIISSPSKDSTK 16 1 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 AAMYDIIS(0.188)S(0.234)PS(0.387)KDS(0.154)T(0.036)K 84.759 0.010623 26668000.0 53593.0 49268.0 44034.0 60302.0 58670.0 66031.0 71742.0 64169.0 66709.0 48859.0 True False 62665.23639000051 54159.00143913127 45083.93755987495 56923.474441721795 47174.03466611896 62568.21811906785 64946.07839289931 62484.63174267556 67684.49292397089 57716.74993236877 1.085737441270173 0.9383584748377829 0.7811239824263029 0.9862557144749744 0.8173369900660807 1.0840565033960492 1.1252552936366256 1.0826082864314726 1.1727010443810868 1.0 15.816702442572117 -6.859106729482348 7.6718905269065765 1.101964408037092 0.9187943404040968 0.48189499431213667 0.08858946628647489 0.19840541003818968 13.682460183729315 0.030882518303307814 0.027258650211487403 1.3832264041708938e-07 6.859106729482348 -0.18317006763299526 AANCNLHVPGPMAVNQFS(ph)PSLAR ddPTM_PC-9_AZD4547_30min_R2 6 AANCNLHVPGPMAVNQFSPSLAR 23 0 Q99990;H0Y5G3 Q99990 VGLL1 Transcription cofactor vestigial-like protein 1 1 AANCNLHVPGPMAVNQFS(0.741)PS(0.259)LAR;AANCNLHVPGPMAVNQFS(0.74)PS(0.26)LAR;AANCNLHVPGPMAVNQFS(0.735)PS(0.265)LAR;AANCNLHVPGPMAVNQFS(0.834)PS(0.166)LAR;AANCNLHVPGPMAVNQFS(0.718)PS(0.282)LAR;AANCNLHVPGPMAVNQFS(0.722)PS(0.278)LAR 132.81 5.4345e-07 119080100.0 95160.2 117701.3 214710.0 328290.0 261426.0 260019.0 243169.0 403896.0 291992.0 293375.0 True False 125419.16414487928 155745.94345062936 211862.80511097846 252607.8125299392 225131.5124412335 243759.97082542232 264810.5699192277 341483.15380675363 307426.10100651736 283104.03054640035 0.44301440676353515 0.55013679300162 0.7483567249186671 0.8922791104118072 0.7952253876665835 0.8610261406556358 0.9353825496872451 1.2062108517059245 1.0859121306509645 1.0 18.110972763447023 -4.89271433696887 0.38378598216093485 1.0987581663202897 6.509795689741537e-18 0.8478872906941983 0.08572341940941793 2.1807724302658276 0.27185147240570096 0.08334385502004811 1.1037209789749007 1.2802231112261116e-05 4.89271433696887 -1.0987581663202897 down AANCNLHVPGPMAVNQFS(ph)PSLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AANCNLHVPGPMAVNQFSPSLAR 23 0 Q99990;H0Y5G3 Q99990 VGLL1 Transcription cofactor vestigial-like protein 1 1 AANCNLHVPGPMAVNQFS(0.751)PS(0.249)LAR;AANCNLHVPGPMAVNQFS(0.853)PS(0.147)LAR;AANCNLHVPGPMAVNQFS(0.711)PS(0.289)LAR 173.24 2.7765e-14 46463700.0 92652.0 96042.0 160224.0 183992.0 211256.0 185171.0 191874.0 197117.0 181627.0 169960.0 True False 108336.15363958571 105576.4150405342 164044.34781290355 173683.52475011203 169861.90331388538 175460.30678508445 173698.3056725376 191942.88761272497 184282.95127047435 200772.4025973798 0.5395968382011063 0.5258512309196823 0.8170662187166774 0.8650766863532005 0.8460420910264197 0.8739264187466286 0.8651503066428137 0.956022267650195 0.9178699307594944 1.0 17.615201450039443 -5.344162913075697 2.6931802020642985 0.8958895224468495 0.5191694471964095 0.9096915606036331 0.045900046967289936 0.07585007754567452 1.054028637832616 0.01296020950519163 0.03577784808881081 4.527277202720826e-06 5.344162913075697 -0.37672007525044005 AANCNLHVPGPMAVNQFS(ph)PSLAR ddPTM_PC-9_Lapatinib_30min_R1 7 AANCNLHVPGPMAVNQFSPSLAR 23 0 Q99990;H0Y5G3 Q99990 VGLL1 Transcription cofactor vestigial-like protein 1 1 AANCNLHVPGPMAVNQFS(0.746)PS(0.254)LAR;AANCNLHVPGPMAVNQFS(0.746)PS(0.254)LAR;AANCNLHVPGPMAVNQFS(0.65)PS(0.35)LAR;AANCNLHVPGPMAVNQFS(0.792)PS(0.208)LAR;AANCNLHVPGPMAVNQFS(0.733)PS(0.267)LAR;AANCNLHVPGPMAVNQFS(0.906)PS(0.094)LAR;AANCNLHVPGPMAVNQFS(0.724)PS(0.276)LAR 157.2 2.3597e-07 109339300.0 385209.0 245683.7 347107.9 303353.0 320458.3 286860.6 272719.3 233317.5 338739.6 234493.1 True False 379715.84902132076 245114.8344874118 318570.0283372421 325662.5915759434 301609.5728392585 274592.24084271915 286839.3709282169 244158.28281741 300587.1791618758 275024.9198925853 1.3806597931911913 0.8912459081276879 1.1583315012387383 1.1841203033642744 1.0966627058997278 0.9984267642000036 1.0429577473933849 0.8877678535922102 1.0929452475771075 1.0 18.06920282098907 -6.667947231046025 3.6175516394083775 0.999017157280014 1.1358435469181298 0.24936806120687194 0.12079191282205408 0.3598866585289967 9.140982150624927 0.04024184393904482 0.03955504035626993 2.148091462142244e-07 6.667947231046025 0.1368263896381159 AANGVVLATEK ddPTM_PC-9_Lapatinib_30min_R1 1 AANGVVLATEK 11 0 P25787;A0A024RA52 P25787 PSMA2 Proteasome subunit alpha type-2;Proteasome subunit alpha type 0 133.81 0.00025513 3516800.0 18335.0 27851.0 18898.0 21078.0 24880.0 20189.0 23128.0 18732.0 20109.0 18791.0 False True 18073.5395377728 27786.512720660343 17344.27938838958 22628.14643414676 23416.607315962025 19325.563532857646 24325.454673826887 19602.35710452804 17844.11266284239 22038.999312566393 0.8200707882171159 1.2607883110562457 0.7869812572887582 1.0267320268595155 1.062507738389471 0.8768802638801493 1.1037458792403874 0.8894395261109244 0.80966074773948 1.0 14.42777109894069 -7.938605674018052 24.994541460288072 0.8864023181605655 0.9935786187571759 0.08025525415757173 0.13949475329451058 142.06602471117426 57836.29517548114 0.07067289885125487 0.03395015558222989 1.1518457546779627e-08 7.938605674018052 0.10717630059661043 AANMLQQS(ph)GSK ddPTM_PC-9_AZD4547_30min_R2 1 AANMLQQSGSK 11 0 P46063 P46063 RECQL ATP-dependent DNA helicase Q1 1 AANMLQQS(1)GSK 88.163 0.0087863 3187600.0 23929.0 24210.0 29106.0 37729.0 31295.0 29053.0 27296.0 36158.0 28628.0 33172.0 True False 31537.924245880244 32035.40904764636 28720.03542247744 29031.16195723926 26950.229441021213 27236.311317215266 29725.291120641334 30570.61192818109 30141.217634779667 32010.658376770985 0.9852319772581188 1.0007732009315164 0.897202271956973 0.9069217388638954 0.8419142500542273 0.8508513319732188 0.9286060527331089 0.9550135323166334 0.9415994285407168 1.0 14.966264729258143 -10.465670283631681 14.750818760686661 0.9999999999140752 0.9207536392028074 0.17952161683575496 0.04906985240312696 0.0 0.0 0.053644357540830086 0.013010667785837749 3.4223917188541453e-11 10.465670283631681 -0.07924636071126778 AANMLQQS(ph)GSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AANMLQQSGSK 11 0 P46063 P46063 RECQL ATP-dependent DNA helicase Q1 1 AANMLQQS(0.999)GS(0.001)K;AANMLQQS(0.989)GS(0.011)K 102.97 0.0027286999999999997 5956000.0 60041.0 58857.0 54299.0 64626.0 68658.0 52942.0 60729.0 50005.0 45131.0 39672.0 True False 70204.7554361954 64699.93398763797 55593.69409010427 61005.21474031889 55204.95776557687 50165.62832093549 54976.30948011469 48692.42173467704 45790.95549553635 46864.219556620796 1.4980459741013044 1.3805827686827958 1.1862716293170448 1.3017439598372722 1.17797668003153 1.0704462550651457 1.1730977278666288 1.039010618236103 0.9770984330638913 1.0 15.516199236852268 -1.5228787466667073 0.23352199187754952 0.9691413005633714 4.017449273943661 0.8772626574519172 0.05667987441777492 16.489867478268035 0.21747511095427954 0.08225589452144283 19.30738903382807 0.029999999904232973 1.5228787466667073 3.048307973380289 AANMLQQS(ph)GSK ddPTM_PC-9_Lapatinib_30min_R1 2 AANMLQQSGSK 11 0 P46063 P46063 RECQL ATP-dependent DNA helicase Q1 1 AANMLQQS(0.996)GS(0.004)K;AANMLQQS(0.944)GS(0.056)K 107.53 0.0044486000000000005 3406800.0 46299.0 48720.0 56619.0 43780.0 40156.0 36934.1 36802.0 29507.3 39071.0 29487.5 True False 45638.76776980327 48607.19183334786 51964.00437566039 46999.72724579868 37794.10302973359 35354.514640592264 38707.42748643104 30878.316879694674 34670.41254413025 34584.37508537605 1.3196354613069632 1.4054668246384285 1.5025283599134134 1.3589873210018601 1.0928086147699332 1.0222684247818568 1.1192172011457977 0.8928400991334241 1.0024877551941247 1.0 15.07783276775218 -6.305219633556905 2.699799377822141 1.009350226837995 1.413826627023048 0.8888182183690001 0.06570026701442173 0.08898090303385306 1.2838190494542998 0.02264048462236285 0.02764523155911006 4.951996926267399e-07 6.305219633556905 0.40447640018505293 AANQVEETLHTHLPQT(ph)PETNFR ddPTM_PC-9_AZD4547_30min_R2 1 AANQVEETLHTHLPQTPETNFR 22 0 Q5VZL5-2;Q5VZL5-4;Q5VZL5 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 AANQVEETLHTHLPQT(0.981)PET(0.019)NFR 87.196 0.0022197 7555000.0 74704.0 69612.0 91941.0 128190.0 104930.0 108020.0 79821.0 98139.0 77227.0 99879.0 True False 98458.31806027149 92112.71766314562 90721.80226681787 98637.77601575716 90362.28072364116 101265.49232387662 86924.91436623351 82973.87255986952 81309.06155795476 96382.26661080145 1.021539765793777 0.9557019242461212 0.9412706865792964 1.023401705357933 0.937540523803311 1.0506651885745122 0.9018766358467434 0.860883183987818 0.8436101828387852 1.0 16.55648010872148 -7.419461727226692 7.593013799853716 0.8876764593466733 0.9838603308834359 0.38715919690556855 0.05242495354553029 0.2537970023010874 16.465035321866626 0.02091494285666342 0.014026573033605804 3.80660902366556e-08 7.419461727226692 0.09618387153676267 AANQVEETLHTHLPQT(ph)PETNFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AANQVEETLHTHLPQTPETNFR 22 0 Q5VZL5-2;Q5VZL5-4;Q5VZL5 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 AANQVEET(0.001)LHT(0.103)HLPQT(0.738)PET(0.159)NFR 63.69 0.037712999999999997 3094300.0 11519.0 13137.0 14181.0 17466.0 16867.0 15282.0 15978.0 15724.0 13680.0 13326.0 True False 13468.939189379504 14441.154540591606 14519.12882174199 16487.436645536003 13562.032430772613 14480.585017576526 14464.448169297566 15311.261660955131 13880.044119982664 15741.898311442046 0.8556108623563884 0.9173705899303777 0.9223238858803146 1.047360128959292 0.8615245863273687 0.9198754007355815 0.9188503116415152 0.9726439186706024 0.8817261962551182 1.0 13.942321905106935 AANQVEETLHTHLPQT(ph)PETNFR ddPTM_PC-9_Lapatinib_30min_R1 3 AANQVEETLHTHLPQTPETNFR 22 0 Q5VZL5-2;Q5VZL5-4;Q5VZL5 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 AANQVEETLHTHLPQT(0.971)PET(0.029)NFR;AANQVEETLHTHLPQT(0.977)PET(0.023)NFR;AANQVEETLHT(0.001)HLPQT(0.981)PET(0.019)NFR 117.11 1.3695e-05 18185300.0 261544.0 212588.0 227342.0 196545.0 236396.0 229417.0 203275.0 211447.0 233002.0 177417.0 True False 257814.33459870477 212095.7655473673 208650.81832549823 210999.57495489944 222491.65205241778 219605.36970714745 213799.58486778644 221271.5995452241 206758.86114016606 208083.29205670723 1.2389958465691937 1.019283016195104 1.0027273995099824 1.0140149786624746 1.069243233578715 1.0553724306096628 1.0274711763476012 1.063379944435533 0.9936350924504778 1.0 17.666801603687695 -4.7596145340378335 24.999882741765752 1.0302372074130255 1.2389961081809002 0.8582297500192559 0.02579397994633391 17.11988928510494 234472.2123972341 0.006553210766817466 0.04126156345611195 1.739343930167824e-05 4.7596145340378335 0.20875890076787473 AAPAQVRPPS(ph)PGNIRPVK ddPTM_PC-9_AZD4547_30min_R2 1 AAPAQVRPPSPGNIRPVK 18 2 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 AAPAQVRPPS(1)PGNIRPVK 67.312 0.036829 23823000.0 7760.3 14685.0 15864.0 15465.0 18493.0 13199.0 14305.0 17615.0 14200.0 14254.0 True False 10227.913975732563 19431.639069173336 15653.632994646547 11899.783181868203 15925.566162415886 12373.664443462787 15578.117287543018 14893.006502431272 14950.583010125438 13754.971798579936 0.7435794217177889 1.4126993027480768 1.1380345393556262 0.8651259599890082 1.1578043485381804 0.8995775945349626 1.1325444730574659 1.0827362440662238 1.0869221128951305 1.0 13.747665561290772 -11.002848389619384 2.781610728650903 0.9976412997639729 1.066046896022153 0.007536767899118502 0.17634406765923347 33847882.879101075 37606330.515968 618093.054674703 0.041129819792511645 9.93462801586199e-12 11.002848389619384 0.0684055962581801 AAPAQVRPPS(ph)PGNIRPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAPAQVRPPSPGNIRPVK 18 2 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 AAPAQVRPPS(1)PGNIRPVK 72.568 0.022229 10821000.0 13905.0 22334.0 24253.0 15685.0 28675.0 14562.0 23103.0 17436.0 20974.0 15947.0 True False 16258.841863731393 24551.171919736076 24831.283500014702 14806.220301456111 23056.339595209847 13798.343085064085 20914.516588764676 16978.32347496908 21280.705071090368 18838.064863617463 0.8630845037131493 1.3032746249405114 1.3181440705182053 0.7859735279950024 1.2239229327498107 0.7324713650239761 1.1102263815407882 0.9012774718575176 1.1296651341396775 1.0 14.201363151556846 -5.751044805972854 24.999909072854045 0.9841045102312311 1.1756783671881565 0.16319740588416687 0.1840075994417255 346.97220351718545 834492.3790529744 0.04721055521249263 0.08064277759461669 1.774006447974767e-06 5.751044805972854 0.19157385695692541 AAPEAS(ph)SPPAS(ph)PLQHLLPGK ddPTM_PC-9_AZD4547_30min_R2 8 AAPEASSPPASPLQHLLPGK 20 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 2 AAPEAS(0.505)S(0.505)PPAS(0.99)PLQHLLPGK;AAPEAS(0.5)S(0.5)PPAS(1)PLQHLLPGK;AAPEAS(0.5)S(0.5)PPAS(1)PLQHLLPGK;AAPEAS(0.501)S(0.501)PPAS(0.998)PLQHLLPGK;AAPEAS(0.515)S(0.515)PPAS(0.97)PLQHLLPGK;AAPEAS(0.5)S(0.5)PPAS(1)PLQHLLPGK;AAPEAS(0.5)S(0.5)PPAS(1)PLQHLLPGK;AAPEAS(0.979)S(0.021)PPAS(0.999)PLQHLLPGK 176.46 2.7844e-08 163484600.0 560674.7 545212.5 686496.1 876641.0 791646.0 720217.0 558570.1 772375.0 602179.4 638922.1 True False 738957.5918417646 721441.7784134615 677392.7131654168 674544.9614184373 681739.6177046401 675181.7171359508 608281.7568063369 653022.191161814 634009.3737103897 616553.6317517506 1.198529298647127 1.1701200694637106 1.0986760571676635 1.0940572347322355 1.1057263838795066 1.0950900008773385 0.9865836895293089 1.0591490464608067 1.0283117981302679 1.0 19.233866869303263 -1.5228787452803376 0.21517660628548757 0.9941456151630114 2.08840788230638 0.8330443364327734 0.026388374491427502 20.30480186932616 0.2563701286943994 0.044383372256356635 7.661244353937528 0.029999999999999995 1.5228787452803376 1.0942622671433688 AAPEAS(ph)SPPAS(ph)PLQHLLPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 9 AAPEASSPPASPLQHLLPGK 20 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 2 AAPEAS(0.503)S(0.503)PPAS(0.993)PLQHLLPGK;AAPEAS(0.653)S(0.653)PPAS(0.694)PLQHLLPGK;AAPEAS(0.5)S(0.5)PPAS(1)PLQHLLPGK;AAPEAS(0.58)S(0.58)PPAS(0.84)PLQHLLPGK;AAPEAS(0.802)S(0.221)PPAS(0.977)PLQHLLPGK;AAPEAS(0.504)S(0.504)PPAS(0.993)PLQHLLPGK;AAPEAS(0.5)S(0.5)PPAS(1)PLQHLLPGK;AAPEAS(0.95)S(0.051)PPAS(0.999)PLQHLLPGK;AAPEAS(0.502)S(0.502)PPAS(0.996)PLQHLLPGK 142.84 1.0371e-09 83492500.0 275284.2 278740.0 287425.6 338213.30000000005 401732.5 410967.0 450793.2 439243.9 423461.1 364784.7 True False 321884.37794921367 306411.4650715152 294278.9163716575 319264.3053033137 323015.9004858807 389415.1670539442 408090.8046358616 427714.21304238145 429653.4174778063 430917.2784759036 0.746974869719022 0.7110679482504189 0.6829127794839938 0.7408946478834837 0.7496007160082891 0.9036889131743643 0.9470281769141953 0.9925668670217844 0.997067044973069 1.0 18.717051421740372 -6.888615798122946 1.5264913769345552 0.9927686038279071 0.7131622535765714 0.9740958814091164 0.020133884384031006 0.055376925196738085 0.2659349543861028 0.009539926643360556 0.007787699887317069 1.2923620658625415e-07 6.888615798122946 -0.27960635025133573 AAPEAS(ph)SPPAS(ph)PLQHLLPGK ddPTM_PC-9_Lapatinib_30min_R1 8 AAPEASSPPASPLQHLLPGK 20 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 2 AAPEAS(0.5)S(0.5)PPAS(1)PLQHLLPGK;AAPEAS(0.522)S(0.522)PPAS(0.956)PLQHLLPGK;AAPEAS(0.5)S(0.5)PPAS(1)PLQHLLPGK;AAPEAS(0.5)S(0.5)PPAS(1)PLQHLLPGK;AAPEAS(0.5)S(0.5)PPAS(0.999)PLQHLLPGK;AAPEAS(0.5)S(0.5)PPAS(1)PLQHLLPGK;AAPEAS(0.59)S(0.437)PPAS(0.973)PLQHLLPGK;AAPEAS(0.506)S(0.506)PPAS(0.989)PLQHLLPGK 149.0 3.7399e-15 171911900.0 530296.0 466482.0 510867.0 479190.3 651667.0 756251.0 736209.0 741186.0 883726.0 687177.0 True False 522733.88179562386 465401.8895895697 468865.48726364685 514431.5531939795 613337.2282866164 723907.9076371837 774326.2997216965 775624.2073925214 784191.471832665 805954.6288442044 0.6485897134746419 0.5774542051541893 0.5817517146542516 0.6382884777666834 0.7610071415138904 0.8981993299986608 0.96075668779536 0.9623670857313905 0.9729970444580122 1.0 19.620339099066143 -6.607916482689193 1.458312909002363 0.9751072791948383 0.5969124256885739 0.9841592838428322 0.021042773091420473 0.044849135361419906 0.19748168035302852 0.009136092732383205 0.009421156684806836 2.466513616293812e-07 6.607916482689193 -0.37819485350626436 AAPEAS(ph)SPPASPLQHLLPGK ddPTM_PC-9_AZD4547_30min_R2 5 AAPEASSPPASPLQHLLPGK 20 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 1 AAPEAS(0.874)S(0.126)PPASPLQHLLPGK;AAPEAS(0.5)S(0.5)PPASPLQHLLPGK;AAPEAS(0.826)S(0.15)PPAS(0.023)PLQHLLPGK;AAPEAS(0.715)S(0.285)PPASPLQHLLPGK;AAPEAS(0.823)S(0.175)PPAS(0.002)PLQHLLPGK 125.73 8.8263e-06 1115761000.0 151080.0 169155.9 321858.0 510552.0 420866.0 343820.0 241639.0 384646.0 278830.0 375391.0 True False 199120.2973407827 223832.23665108497 317589.95262171875 392852.12434976886 362436.0205759652 322320.88104791136 263144.40288323 325207.7989857606 293568.384557273 362248.67535012733 0.54967846921269 0.6178966325680625 0.8767180509763239 1.0844818796647417 1.00051717297698 0.8897779425594193 0.7264192274240638 0.8977473793974118 0.8104056813279658 1.0 18.466620888665403 -5.24246175846795 3.854281104578636 0.9111493523440213 0.5686606077868872 0.6548161063532429 0.09571462093496061 0.1427582597875535 4.814550313640893 0.02780986820218642 0.07649206928445283 5.7218733603619475e-06 5.24246175846795 -0.3424887445571341 AAPEAS(ph)SPPASPLQHLLPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 AAPEASSPPASPLQHLLPGK 20 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 1 AAPEAS(0.835)S(0.164)PPASPLQHLLPGK;AAPEAS(0.879)S(0.121)PPASPLQHLLPGK;AAPEAS(0.905)S(0.076)PPAS(0.019)PLQHLLPGK;AAPEAS(0.793)S(0.188)PPAS(0.019)PLQHLLPGK;AAPEAS(0.859)S(0.141)PPASPLQHLLPGK;AAPEAS(0.91)S(0.09)PPASPLQHLLPGK;AAPEAS(0.826)S(0.173)PPAS(0.001)PLQHLLPGK 168.3 1.7928999999999998e-08 969854300.0 401936.5 488125.0 715918.0 798429.0 918963.0 839152.0 787128.0 726664.0 753339.0 618587.0 True False 469976.4108422641 536582.8240942592 732988.2002541353 753695.6116717443 738898.7969810934 795145.3918773308 712565.5375267795 707589.839964149 764355.1576976342 730731.9263680013 0.6431584468715015 0.7343087180565211 1.0030876903070987 1.0314255946334256 1.0111762882096644 1.0881492421297199 0.9751394619754535 0.9683302650824679 1.0460130864909 1.0 19.478982715865726 -5.192834984129226 3.0791126593548768 1.0181591100532417 0.6563522315440303 0.9398815484434722 0.03340690704279917 0.05644282733953608 1.03191123584056 0.009224355176290678 0.030385842395344233 6.414532588456689e-06 5.192834984129226 -0.36180687850921134 AAPEAS(ph)SPPASPLQHLLPGK ddPTM_PC-9_Lapatinib_30min_R1 6 AAPEASSPPASPLQHLLPGK 20 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 1 AAPEAS(0.956)S(0.044)PPASPLQHLLPGK;AAPEAS(0.534)S(0.41)PPAS(0.055)PLQHLLPGK;AAPEAS(0.806)S(0.184)PPAS(0.01)PLQHLLPGK;AAPEAS(0.674)S(0.325)PPAS(0.001)PLQHLLPGK;AAPEAS(0.795)S(0.164)PPAS(0.041)PLQHLLPGK;AAPEAS(0.564)S(0.435)PPAS(0.001)PLQHLLPGK 195.05 1.1800999999999998e-15 785288900.0 471159.6 360171.2 549186.6 382855.6 517117.2 476646.4 340878.80000000005 399281.8 555918.2 350139.5 True False 464440.77770391176 359337.24571525306 504034.59766958083 411012.07799284224 486701.3829875317 456261.3445890274 358527.83633122157 417833.89007787424 493304.8382378316 410660.64604344236 1.1309600327633542 0.8750223552642052 1.2273749689086613 1.0008557721631859 1.1851668468276975 1.1110422899903614 0.8730513619590764 1.01746757110413 1.2012469249017024 1.0 18.64758717369361 AAPEASS(ph)PPAS(ph)PLQHLLPGK ddPTM_PC-9_AZD4547_30min_R2 5 AAPEASSPPASPLQHLLPGK 20 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 2 AAPEAS(0.165)S(0.836)PPAS(0.999)PLQHLLPGK;AAPEAS(0.443)S(0.563)PPAS(0.994)PLQHLLPGK;AAPEAS(0.443)S(0.558)PPAS(1)PLQHLLPGK;AAPEAS(0.443)S(0.557)PPAS(1)PLQHLLPGK;AAPEAS(0.428)S(0.572)PPAS(1)PLQHLLPGK 157.98 2.9175e-20 29408500.0 96458.6 86007.3 111873.29999999999 154700.0 126137.1 118633.70000000001 87188.5 128426.5 102871.8 112345.9 True False 127130.42833648111 113807.47776057973 110389.78694528443 119036.30509117419 108625.14094983354 111215.5159850313 94948.10759349483 108581.13537238068 108309.39333105781 108412.70423643039 1.1726524970655692 1.0497614515028075 1.0182366330844617 1.0979922134547577 1.0019595186274466 1.0258531670097302 0.8758024095259954 1.0015536106873875 0.9990470590499497 1.0 16.72617430183856 -1.5228787468175013 0.3967467572977506 0.9744346855428621 3.827275749869921 0.5520596933646119 0.048458475813579815 57.2411311268338 0.7631639732258502 0.036550470935618515 127.31109816787355 0.02999999989381649 1.5228787468175013 2.852841064327059 AAPEASS(ph)PPAS(ph)PLQHLLPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAPEASSPPASPLQHLLPGK 20 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 2 AAPEAS(0.455)S(0.545)PPAS(1)PLQHLLPGK 100.62 0.00068363 21952000.0 96572.0 101700.0 101610.0 144050.0 135110.0 116740.0 95704.0 122680.0 100640.0 110170.0 True False 112919.73221605687 111796.10388811471 104032.7677580711 135979.34551640085 108636.16539525008 110617.94889097521 86638.22428304264 119459.77999020478 102111.66960782565 130142.94889475987 0.8676592406659652 0.8590254396226925 0.7993730635548856 1.0448460456075925 0.8347449194738836 0.8499726633705407 0.6657158533659988 0.917912042140723 0.7846116172640154 1.0 16.989737623519353 -6.483185033383695 24.998917231129973 0.8290543975823881 0.8906687868262576 0.048792868307782844 0.09992325626591397 1448.2603313817717 912107.9247254519 0.03020013209701746 0.03423886654600478 3.287115518007091e-07 6.483185033383695 0.06161438924386953 AAPEASS(ph)PPAS(ph)PLQHLLPGK ddPTM_PC-9_Lapatinib_30min_R1 2 AAPEASSPPASPLQHLLPGK 20 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 2 AAPEAS(0.541)S(0.636)PPAS(0.823)PLQHLLPGK;AAPEAS(0.36)S(0.64)PPAS(1)PLQHLLPGK 111.63 0.00063664 8523600.0 16579.2 13934.0 18979.4 11612.900000000001 21479.9 24481.6 24193.6 24698.0 27299.8 22678.0 True False 16342.777567747089 13901.736679102407 17418.98699460267 12466.951405498767 20216.49451310822 23434.57903739697 25446.226227806044 25845.559244481818 24225.00904436146 26597.86208346444 0.6144395183516344 0.5226636876106273 0.6549017714259011 0.4687200560096639 0.7600796804520829 0.8810700259990428 0.956701938973721 0.9717156650928602 0.9107878282977431 1.0 14.699022667172917 -6.611586310466675 2.285819593963446 0.9516028039196546 0.5682780558642979 0.9093707276929633 0.056314755788675945 0.07766738206054082 0.8258393647695687 0.019410017582220676 0.019704346508415543 2.4457591644352656e-07 6.611586310466675 -0.38332474805535666 AAPEASSPPAS(ph)PLQHLLPGK ddPTM_PC-9_AZD4547_30min_R2 1 AAPEASSPPASPLQHLLPGK 20 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 1 AAPEAS(0.259)S(0.048)PPAS(0.694)PLQHLLPGK 120.33 6.664400000000001e-06 14027000.0 83918.0 80240.0 107800.0 146310.0 108830.0 101320.0 82864.0 114150.0 84775.0 93773.0 True False 110602.1783971658 106176.01082127815 106370.50156473133 112580.48996696643 93720.83304254143 94984.44438303258 90238.73547116146 96510.74040604742 89256.03342840743 90490.03581227972 1.2222580906765075 1.1733447762308191 1.1754940818610726 1.2441202940897609 1.0357033479019055 1.0496674416183949 0.9972228948871279 1.0665344481270576 0.9863631131008479 1.0 16.465471320080773 -6.273212017519823 23.839054517272537 1.0259949030678668 1.1996064668172322 0.8959431476145971 0.03022912713068453 116.39623105117433 235696.49147895054 0.008966431081457787 0.010259684876034575 5.330745911326271e-07 6.273212017519823 0.17361156374936537 AAPEASSPPAS(ph)PLQHLLPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAPEASSPPASPLQHLLPGK 20 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 1 AAPEAS(0.008)S(0.001)PPAS(0.991)PLQHLLPGK 89.62200000000001 0.00039056 11100000.0 78217.0 90183.0 110480.0 108020.0 162290.0 155080.0 175880.0 167680.0 168220.0 134950.0 True False 91457.59324383161 99135.77224131649 113114.26219773339 101967.9896055652 130490.43950851304 146947.33179726268 159219.37313906947 163278.57767164544 170679.8992590263 159415.36673638763 0.5737062562799713 0.6218708664720468 0.7095568295168266 0.639637142222189 0.8185562168814916 0.9217890019364172 0.9987705476496362 1.0242336169614445 1.070661522494666 1.0 17.282431178080373 -6.613963608356313 1.0373768821696663 1.0413832913334808 0.6135768397923121 0.9617947324856426 0.035004151126390264 0.08852120525874614 0.2047839838238598 0.01820718778067342 0.019215908239192128 2.4324078237983523e-07 6.613963608356313 -0.4278064515411687 AAPEASSPPAS(ph)PLQHLLPGK ddPTM_PC-9_Lapatinib_30min_R1 1 AAPEASSPPASPLQHLLPGK 20 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 1 AAPEASSPPAS(1)PLQHLLPGK 136.59 6.453600000000001e-05 9713200.0 38545.0 39207.0 42340.0 37349.0 50135.0 50825.0 51072.0 45401.0 59682.0 42619.0 True False 37995.3412317127 39116.21860037089 38858.96863712641 40095.77005261157 47186.157869202405 48651.33322886172 53716.25826278475 47510.496204499126 52959.984680678244 49985.63736375213 0.7601251726614097 0.7825491613864392 0.7774026837818337 0.8021458196247319 0.9439943223254804 0.9733062494496068 1.0746338567593805 0.9504829529082309 1.0595040390358812 1.0 15.609225996822271 -6.371505080972168 1.7445754498384443 1.0157921961811334 0.7706810299501663 0.9141372275119649 0.03369392962504222 0.09071278032088695 0.5480458096740034 0.011641867582418308 0.014237332053575259 4.251037333293301e-07 6.371505080972168 -0.24511116623096707 AAPFSLEYR ddPTM_PC-9_AZD4547_30min_R2 2 AAPFSLEYR 9 0 Q15181;Q5SQT6 Q15181 PPA1 Inorganic pyrophosphatase 0 ; 111.65 0.010232999999999999 14009700.0 28772.0 18717.2 41035.0 84824.0 57564.0 35878.0 30070.0 49864.0 32812.0 35217.0 False True 37920.89750522237 24767.16886520472 40490.84908820731 65269.137317736146 49572.23222696741 33634.54298829895 32746.17174669126 42158.66456072851 34546.375332974385 33984.06354922054 1.1158435320808515 0.728787739857342 1.1914657889443598 1.9205807222907327 1.4586905463841862 0.9897151628022539 0.9635743441705731 1.2405421882426848 1.016546337460187 1.0 15.052570748604872 -6.780241618619241 24.946496144292272 1.0522031325103665 1.2826077785978702 0.14812822340730125 0.2884573690629656 589.4855464578571 782114.3165627467 0.1159751334444367 0.102451718411847 1.6586638573174174e-07 6.780241618619241 0.23040464608750377 AAPFSLEYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAPFSLEYR 9 0 Q15181;Q5SQT6 Q15181 PPA1 Inorganic pyrophosphatase 0 101.33 0.008373 0.0 5193.9 5519.0 6378.1 6464.2 7825.5 6628.7 6602.3 6219.4 4822.7 6335.7 False True 6073.12468579896 6066.8898461996705 6530.178093078946 6102.031831219166 6292.149450821783 6281.07930284057 5976.882347487378 6056.147339999005 4893.222863847977 7484.312256626398 0.811447261626743 0.8106142071809227 0.8725154522110313 0.8153096265881477 0.8407117761890402 0.8392326625976194 0.7985880522549839 0.8091788707288454 0.6537972623357151 1.0 12.869654035876898 -7.268815780440454 22.24407903234174 0.7994892764589642 0.832211090525931 0.0 0.08028364804594931 523.1872276704423 1577683.366660003 0.031081914573835294 0.021499457870215562 5.384981548770384e-08 7.268815780440454 0.03272181406696684 AAPFSLEYR ddPTM_PC-9_Lapatinib_30min_R1 2 AAPFSLEYR 9 0 Q15181;Q5SQT6 Q15181 PPA1 Inorganic pyrophosphatase 0 ; 110.12 0.010704 13914000.0 34029.0 28813.0 31335.0 28095.0 35434.0 36622.0 25962.0 25537.0 36324.0 30332.0 False True 33543.740219845684 28746.28526876546 28758.757256597928 30161.20002217256 33349.84178592437 35055.76243005162 27306.185326958377 26723.542247401918 32232.80861132264 35574.845785150515 0.9429061315522934 0.8080508751148149 0.808401459567318 0.8478237742568742 0.9374556951655179 0.9854086969699368 0.7675700266382152 0.7511920756816529 0.9060561725548536 1.0 15.118569882317207 -12.18308364931484 1.4252584343895132 2.2401492172063766 0.8579549311173006 0.231710667262644 0.07530681646398288 616638.7769116602 29139.793117571367 2454722.039319968 0.02236811694058278 6.560188985529315e-13 12.18308364931484 -1.3821942860890761 AAPGAEFAPNKR ddPTM_PC-9_AZD4547_30min_R2 2 AAPGAEFAPNKR 12 1 Q15233;Q15233-2 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 ; 96.64 0.0026704999999999997 15397200.0 41688.0 44258.0 61662.0 78468.0 73960.0 62042.0 52905.0 62272.0 48781.0 60904.0 False True 54943.91683573304 58563.5329876387 60844.32159076489 60378.41491851496 63691.930642528445 58162.50393221594 57613.44250943467 52649.29326820324 51359.464071614755 58771.76949773487 0.9348691949431714 0.9964568616552509 1.0352644153943655 1.027337026509675 1.083716403076535 0.9896333635906196 0.980291098971508 0.8958262396750263 0.8738798322823036 1.0 15.842835715125997 -7.541671537058065 2.8130916962800403 0.9141505746846835 1.0153188006022442 0.40037140128254056 0.04721000500436413 0.24789158947103468 3.977074357043653 0.02555296832822213 0.013995973262863979 2.87295261447283e-08 7.541671537058065 0.1011682259175607 AAPGAEFAPNKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AAPGAEFAPNKR 12 1 Q15233;Q15233-2 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 ; 120.77 0.00030215 11798300.0 68615.0 47984.0 67840.0 78355.0 82057.0 67328.0 74010.0 78333.0 69138.0 54393.0 False True 80230.1642919763 52747.53440479162 69457.56288463283 73965.02338033734 65978.51990110324 63797.20115582989 66999.23701400128 76276.84175067396 70149.01245375439 64254.02032524894 1.2486403790121978 0.8209219304533418 1.0809839218315673 1.1511345594553002 1.0268387809373642 0.9928904188857497 1.0427244345934505 1.1871139169901965 1.0917451094680994 1.0 15.971499105013033 AAPGAEFAPNKR ddPTM_PC-9_Lapatinib_30min_R1 2 AAPGAEFAPNKR 12 1 Q15233;Q15233-2 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 ; 119.45 0.00034062 25796000.0 105108.0 88099.0 104684.0 106128.0 105759.0 102883.0 95012.0 76227.0 95169.0 94321.0 False True 103609.14064555363 87895.01217828644 96077.28561192601 113933.0071526295 99538.46355019392 98482.93392198673 99931.2564627135 79768.7847003447 84450.06504600175 110624.25917516756 0.936586074501924 0.7945365043223424 0.8685010532797585 1.029909786534459 0.8997887469924668 0.8902471723317423 0.9033394411661345 0.7210785888657126 0.7633955307423086 1.0 16.755308268272984 -7.712790908665998 24.878046735439135 0.8066777114428787 0.9019889641877884 0.11959869486204555 0.08771930961263949 168.68862832615534 86264.29756341917 0.04089386774228544 0.023610014824261828 1.9373544799033796e-08 7.712790908665998 0.0953112527449097 AAPPPPALT(ph)PDSQTVDSSCK ddPTM_PC-9_AZD4547_30min_R2 2 AAPPPPALTPDSQTVDSSCK 20 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 AAPPPPALT(1)PDSQTVDSSCK;AAPPPPALT(0.999)PDSQT(0.001)VDSSCK 129.89 8.1451e-05 17442500.0 38436.0 35082.0 55748.0 55773.0 44739.0 48775.0 42866.0 53434.0 39521.0 43171.0 True False 50657.84848153506 46421.57043409872 55008.74509490392 42915.3965342603 38527.76210135318 45725.09153950275 46680.990957554604 45177.003091167324 41609.999376279404 41659.59643022974 1.215994700437757 1.114306772314614 1.3204339410015873 1.0301443175555896 0.9248232196842889 1.097588441983152 1.120533921535571 1.0844320867780952 0.9988094686890834 1.0 15.346361243149653 -5.786647078007601 24.990834162593284 1.041515446859014 1.206651318462048 0.5750576214311918 0.07077073954752984 169.9037418030466 168441.40461520592 0.020577087180840538 0.03053409432200735 1.6343795590223147e-06 5.786647078007601 0.165135871603034 AAPPPPALT(ph)PDSQTVDSSCK ddPTM_PC-9_Lapatinib_30min_R1 2 AAPPPPALTPDSQTVDSSCK 20 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 AAPPPPALT(0.854)PDS(0.075)QT(0.041)VDS(0.023)S(0.007)CK;AAPPPPALT(0.879)PDS(0.066)QT(0.046)VDS(0.007)S(0.002)CK 141.6 4.1661999999999995e-05 18496800.0 63868.0 102554.0 110187.0 105919.0 119328.0 109671.0 104879.0 108730.0 110835.0 92576.0 True False 62957.23060804326 102316.54251389895 101127.85019412026 113708.63659542626 112309.36164787452 104980.6269855876 110309.12144311181 113781.9927383803 98351.59515570827 108577.63825023395 0.5798360659028942 0.9423353110526742 0.9313874553161259 1.0472564924774577 1.034369170832766 0.966871527852204 1.0159469594364117 1.0479321025214428 0.9058181476469567 1.0 16.728367482667593 -4.4418954659754 1.691152545512322 1.0007052287606677 1.8040339321193603e-17 0.8779512162501776 0.04589731026913264 0.8281135586016725 1.110398200316749 0.012237859011916413 1.7839009278306464 3.614968639167665e-05 4.4418954659754 -1.0007052287606677 AAPPPPPPPPPLES(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 3 AAPPPPPPPPPLESSPR 17 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 AAPPPPPPPPPLES(0.5)S(0.5)PR;AAPPPPPPPPPLES(0.5)S(0.5)PR;AAPPPPPPPPPLES(0.5)S(0.5)PR 150.92 4.8658e-05 70176200.0 24017.7 27017.7 46372.2 66291.8 52170.8 38457.8 32130.3 41824.2 39685.0 40693.0 True False 31654.829000805636 35750.64316508033 45757.274328942745 51009.24970810027 44927.78495355903 36053.02768647648 34989.83445536131 35361.23091450385 41782.66808146679 39268.35045598521 0.8061155773855753 0.9104187660022088 1.1652456443320884 1.2989914044205935 1.1441220329312616 0.9181192300625745 0.8910441627687019 0.9005020711053108 1.0640291124094916 1.0 15.261079375594171 -6.773266197947696 24.987605104161833 0.9445393537162554 1.0749631195045986 0.1367694973724385 0.13613565236785446 452.0271953384874 955033.5094238669 0.05373837906290794 0.04776725750913775 1.6855195805529396e-07 6.773266197947696 0.13042376578834314 AAPPPPPPPPPLES(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 AAPPPPPPPPPLESSPR 17 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 AAPPPPPPPPPLES(0.5)S(0.5)PR;AAPPPPPPPPPLES(0.824)S(0.176)PR;AAPPPPPPPPPLES(0.5)S(0.5)PR;AAPPPPPPPPPLES(0.5)S(0.5)PR;AAPPPPPPPPPLES(0.5)S(0.5)PR;AAPPPPPPPPPLES(0.5)S(0.5)PR 157.37 2.7915e-05 104914300.0 101515.59999999999 115265.0 106834.5 133045.1 151861.0 126027.5 128139.4 112516.79999999999 115999.8 94189.79999999999 True False 118700.18605550606 126707.74744015334 109381.83965209755 125591.0143850341 122104.92719330975 119418.39604126586 116001.10838308213 109563.35322140413 117696.07762493877 111265.66513395328 1.0668177457313748 1.1387856917730124 0.9830691212820434 1.1287490551001016 1.0974178516463908 1.0732726569108042 1.0425597891625222 0.9847004742163746 1.0577933227042131 1.0 16.76364894238158 -7.37363886895145 2.9782641770333513 1.0156123211896892 1.0828692696019422 0.32787617995039253 0.04336727701096421 0.316747367467803 5.389955855325368 0.01987017701670801 0.012488804729951944 4.230202241663711e-08 7.37363886895145 0.06725694841225294 AAPPPPPPPPPLES(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 2 AAPPPPPPPPPLESSPR 17 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 AAPPPPPPPPPLES(0.5)S(0.5)PR;AAPPPPPPPPPLES(0.5)S(0.5)PR 137.27 3.812e-05 134202000.0 100859.0 90320.0 89073.0 76934.0 77554.0 90335.0 67007.0 70607.0 88610.0 60226.0 True False 99420.73216472463 90110.86958924423 81749.7617717232 82591.98300430046 72992.42619703042 86471.58263117018 70476.29459223103 73887.65898352602 78629.80869533356 70635.98385389936 1.407508280345645 1.275707715427677 1.1573387572658596 1.1692621592859866 1.0333603669767668 1.2241860014298738 0.9977392647068012 1.0460342583512716 1.1131692999133176 1.0 16.108115697638087 -1.5228787452845884 0.41250214194672224 1.0500068367033835 7.469437603885785 0.7622624019107302 0.06146683868808308 35.27396066552335 0.45818481368437886 0.041238639288902965 185.8131384588294 0.02999999999970636 1.5228787452845884 6.419430767182401 AAPPPPPPPPPLESS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 AAPPPPPPPPPLESSPR 17 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 AAPPPPPPPPPLES(0.339)S(0.661)PR 116.04 0.00014513 74420000.0 29259.0 29568.0 52122.0 45116.0 43365.0 38368.0 24597.0 34732.0 34014.0 26496.0 True False 38562.75337499312 39125.27776624567 51430.82822409018 34715.20323525157 37344.51828438679 35968.842894672314 26786.085349297136 29364.967461960983 35811.91059904271 25568.383104754717 1.508220258473128 1.5302210392400568 2.0115010015837123 1.3577394821182847 1.460574105581286 1.4067703361337511 1.0476253128542952 1.1484874636636782 1.4006325880021369 1.0 14.64207330976109 -6.661021164715508 1.2047709443298296 1.1629442038011526 1.6419205188439636 0.5400867476740234 0.1862048008226577 0.36699558640389174 1.1255780449431194 0.09083928632823875 0.09011320119654762 2.182623542239221e-07 6.661021164715508 0.478976315042811 AAPQS(ph)PSVPK ddPTM_PC-9_AZD4547_30min_R2 4 AAPQSPSVPK 10 0 E9PF10;O75694-2;O75694 E9PF10 NUP155 Nuclear pore complex protein Nup155 1 AAPQS(0.543)PS(0.457)VPK;AAPQS(0.5)PS(0.5)VPK;AAPQS(0.958)PS(0.042)VPK;AAPQS(0.968)PS(0.032)VPK 139.31 0.00012086 351205000.0 255535.0 208690.0 277213.0 307237.0 241517.0 239033.0 253100.0 313942.0 268922.0 237593.0 True False 336789.814541812 276144.96134462307 273536.97449224384 236408.25641433147 207986.53343687844 224086.2287229512 275625.40968033165 265429.4775694729 283136.66790485603 229274.94138768042 1.4689342520530186 1.2044271374501858 1.1930522055165238 1.0311124930769882 0.9071489983948771 0.9773690372208813 1.202161073565721 1.1576907444091715 1.2349219944891445 1.0 17.806719158569358 -4.607836298933231 1.3151980461899302 1.079811966119109 1.759360745440424 0.5734641118460506 0.1012661720729609 1.6157772029999056 1.8549778249444098 0.033257156060597225 1.6441253681207255 2.4669690505504758e-05 4.607836298933231 0.6795487793213151 AAPQS(ph)PSVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AAPQSPSVPK 10 0 E9PF10;O75694-2;O75694 E9PF10 NUP155 Nuclear pore complex protein Nup155 1 AAPQS(0.983)PS(0.017)VPK;AAPQS(0.978)PS(0.022)VPK;AAPQS(0.682)PS(0.318)VPK;AAPQS(0.935)PS(0.065)VPK 141.71 0.00011643 402080000.0 484632.0 481595.0 407516.0 437070.0 500325.0 397347.0 511658.0 441254.0 396217.0 362102.0 True False 566670.6256816873 529404.5688495254 417232.7269530355 412582.38490005897 402289.9078630641 376509.42383058346 463190.05015686905 429671.55004725803 402010.92405607883 427748.22620214603 1.3247760971751852 1.23765462115403 0.9754166151839492 0.964544934676316 0.9404829365042163 0.8802127063705273 1.082856740913693 1.004496392333847 0.9398307215097504 1.0 18.70640234655729 -5.185837587841472 3.246610389091638 0.9710972697836278 1.3106015431639702 0.8587856708458076 0.05040965407842944 0.08844192312428396 1.788016063136023 0.014026889277491685 0.04539515407760711 6.518721276790819e-06 5.185837587841472 0.3395042733803424 AAPQS(ph)PSVPK ddPTM_PC-9_Lapatinib_30min_R1 5 AAPQSPSVPK 10 0 E9PF10;O75694-2;O75694 E9PF10 NUP155 Nuclear pore complex protein Nup155 1 AAPQS(0.987)PS(0.013)VPK;AAPQS(0.583)PS(0.417)VPK;AAPQS(0.541)PS(0.459)VPK;AAPQS(0.831)PS(0.169)VPK;AAPQS(0.959)PS(0.041)VPK 135.1 0.00011277 640558000.0 494237.0 646132.0 583395.0 522587.0 666346.0 631630.0 706502.0 631499.0 705435.0 557381.0 True False 487189.08974803507 644635.921052233 535430.5150698232 561019.7912791284 627152.8383666412 604616.6573014448 743081.2166191653 660840.748940443 625981.4817401277 653723.5631865012 0.7452524540698628 0.9860986468195034 0.8190472934154738 0.8581911726487282 0.9593548002303237 0.9248812362741059 1.136690274704342 1.010887148872606 0.9575629776733947 1.0 19.318321173875283 -6.632877299552822 1.6571664754348367 1.0229728489678631 0.8594525739990052 0.49187665423783533 0.07462499822902403 0.3182600467095241 1.7999493277056455 0.029780869344753453 0.029975950009495617 2.3287491020708017e-07 6.632877299552822 -0.1635202749688579 AAPQSPS(ph)VPK ddPTM_PC-9_AZD4547_30min_R2 2 AAPQSPSVPK 10 0 E9PF10;O75694-2;O75694 E9PF10 NUP155 Nuclear pore complex protein Nup155 1 AAPQS(0.291)PS(0.709)VPK;AAPQS(0.087)PS(0.913)VPK 149.94 0.00015853 385705000.0 246969.0 218903.0 224896.0 266280.0 212000.0 229687.0 237240.0 287560.0 239171.0 215074.0 True False 325500.00472568057 289659.1138685226 221913.732095564 204893.2599849895 182567.45938637122 215324.6355803947 258353.90040522174 243124.2094714244 251813.09078272598 207544.3247234312 1.5683397036244398 1.395649407684434 1.0692353664272976 0.9872265129775317 0.8796552718541276 1.0374874661946616 1.244813129674821 1.1714327038111312 1.2132978876598353 1.0 17.663059956581627 -5.113917244899554 2.933782938886532 1.0749986780083194 1.5513783218823307 0.71197210563776 0.105934613672143 0.16530888734245514 2.6102026698264464 0.032222735595727796 0.12516365507427626 7.692770125644161e-06 5.113917244899554 0.4763796438740113 AAPQSPS(ph)VPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AAPQSPSVPK 10 0 E9PF10;O75694-2;O75694 E9PF10 NUP155 Nuclear pore complex protein Nup155 1 AAPQS(0.259)PS(0.741)VPK;AAPQS(0.131)PS(0.869)VPK 134.3 0.00011124 145950000.0 156729.0 122450.0 120653.0 129301.0 147463.0 112441.0 136709.0 132126.0 116120.0 94750.0 True False 183260.1241611478 134606.0267561423 123529.82509905078 122056.68416949805 118568.683722003 106544.39601893237 123758.93383255113 128657.83249906867 117818.03532254274 111927.42495941273 1.6373120727793196 1.202618811296278 1.1036600292005765 1.0904984566004123 1.0593354020696761 0.9519060771528304 1.1057069692921888 1.1494754975889308 1.052628838421558 1.0 16.772204049671977 -4.399440856133331 1.4348562292242644 1.0626962554361998 2.51148537609723 0.9154907218401606 0.05242185849533213 0.8659286584876315 0.7901291493813113 0.015742117633832875 2.3530615501286536 3.986200542052119e-05 4.399440856133331 1.4487891206610304 AAPRPAPVAQPPAAAPPSAVGS(ph)SAAAPR ddPTM_PC-9_AZD4547_30min_R2 1 AAPRPAPVAQPPAAAPPSAVGSSAAAPR 28 1 Q9Y6H1;Q5T1J5 Q9Y6H1 CHCHD2;CHCHD2P9 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2;Putative coiled-coil-helix-coiled-coil-helix domain-containing protein CHCHD2P9, mitochondrial 1 AAPRPAPVAQPPAAAPPS(0.023)AVGS(0.488)S(0.488)AAAPR 98.71799999999999 4.4601e-05 0.0 4810.9 5028.8 5739.3 10457.0 7225.8 13237.0 18158.0 9554.7 12487.0 9390.5 True False 6340.666127063612 6654.261256456173 5663.193132008 8046.300209039496 6222.622396386995 12409.288297455625 19774.026823292974 8078.240660163501 13147.03732728425 9061.741453245748 0.6997182781895088 0.7343247752972184 0.6249563796569753 0.8879419315320964 0.6866916727312019 1.3694154000620762 2.182144229706563 0.8914666901327255 1.4508290040183418 1.0 13.14557261357989 -6.780750880238519 7.228994351025848 1.4247705896887952 0.7297769196919286 0.49361864536245803 0.3286708148281862 0.1344535687839472 30.198376915433645 0.11359005989198297 0.10315972119328431 1.6567200177826695e-07 6.780750880238519 -0.6949936699968666 AAPSTAPAEAT(ph)PPKPGEAEAPPK ddPTM_PC-9_AZD4547_30min_R2 3 AAPSTAPAEATPPKPGEAEAPPK 23 1 O95817 O95817 BAG3 BAG family molecular chaperone regulator 3 1 AAPS(0.007)T(0.006)APAEAT(0.988)PPKPGEAEAPPK;AAPS(0.001)T(0.001)APAEAT(0.999)PPKPGEAEAPPK;AAPSTAPAEAT(1)PPKPGEAEAPPK 103.9 2.0534e-06 73125400.0 166847.0 202668.0 193282.0 146770.0 152040.0 214066.0 193646.0 195278.0 184847.0 173199.0 True False 219900.87536680876 268176.46761125146 190718.95439178453 112934.44407389563 130931.87040143354 200680.41917980943 210880.1188579905 165102.27214202518 194617.63504737036 167135.35572767296 1.315705312077182 1.6045466050176296 1.141104786365718 0.6757064870098987 0.7833882294466249 1.2007059685611592 1.261732551678619 0.987835706114986 1.1644312730842927 1.0 17.35065742709113 -5.433202488381985 5.55582874062337 1.0112429136739034 1.4514361521556094 0.48707906376876353 0.18178381232197147 0.19703885558779063 9.470049134645208 0.05239633318843084 0.11072736624683187 3.6880560407047637e-06 5.433202488381985 0.440193238481706 AAPSTAPAEAT(ph)PPKPGEAEAPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AAPSTAPAEATPPKPGEAEAPPK 23 1 O95817 O95817 BAG3 BAG family molecular chaperone regulator 3 1 AAPSTAPAEAT(1)PPKPGEAEAPPK;AAPS(0.006)T(0.02)APAEAT(0.974)PPKPGEAEAPPK;AAPSTAPAEAT(1)PPKPGEAEAPPK;AAPSTAPAEAT(1)PPKPGEAEAPPK 127.01 2.9334e-07 60073000.0 270523.0 394025.0 256254.0 273692.0 292247.0 207175.0 304706.0 203161.0 216637.0 189150.0 True False 316317.2008271999 433141.1979794929 262364.067208707 258357.92456143667 234983.29826264374 196310.3782892567 275842.0417995985 197828.2390168732 219804.90628806112 223441.39768942332 1.415660679257257 1.9385002173211692 1.1741963213700668 1.1562670446617338 1.0516551574263928 0.8785765767636403 1.2345162742985096 0.8853696811002247 0.9837250776312417 1.0 17.769536977662895 -5.419875846191004 4.745750965533799 1.0341384792303545 1.6724426157016257 0.7267854441765857 0.15670713950217002 0.10326943834640039 3.6828717819185455 0.039914821458907256 0.08578726676044504 3.802980983907621e-06 5.419875846191004 0.6383041364712712 AAPSTAPAEAT(ph)PPKPGEAEAPPK ddPTM_PC-9_Lapatinib_30min_R1 4 AAPSTAPAEATPPKPGEAEAPPK 23 1 O95817 O95817 BAG3 BAG family molecular chaperone regulator 3 1 AAPS(0.002)T(0.004)APAEAT(0.994)PPKPGEAEAPPK;AAPS(0.006)T(0.021)APAEAT(0.973)PPKPGEAEAPPK;AAPSTAPAEAT(1)PPKPGEAEAPPK;AAPSTAPAEAT(1)PPKPGEAEAPPK 113.49 7.045e-08 88184000.0 110201.3 268014.0 247746.0 257240.0 336204.0 287892.0 352992.0 335669.0 244517.0 253702.0 True False 108629.80925355652 267393.43004973116 227377.2802072159 276158.2877274837 316429.14172249555 275579.5302690303 371268.1985568793 351265.4071599315 216976.92058184076 297554.05266333406 0.36507588547773917 0.8986381723130891 0.7641545398962544 0.9280945268789249 1.0634341521824864 0.9261494770526056 1.2477336310285403 1.1805095713395268 0.7292016984468302 1.0 18.182792241768254 -4.594968589049366 0.8283659772344332 1.0356361902394597 5.189403879262965e-17 0.576274475911156 0.15547830412568314 2.3916333197871267 1.0276553137109512 0.057044333706197846 2.4420042800906585 2.541156491569974e-05 4.594968589049366 -1.0356361902394597 AAPSTAPAEAT(ph)PPKPGEAEAPPKHPGVLK ddPTM_PC-9_AZD4547_30min_R2 2 AAPSTAPAEATPPKPGEAEAPPKHPGVLK 29 2 O95817 O95817 BAG3 BAG family molecular chaperone regulator 3 1 AAPS(0.007)T(0.052)APAEAT(0.941)PPKPGEAEAPPKHPGVLK;AAPS(0.105)T(0.091)APAEAT(0.804)PPKPGEAEAPPKHPGVLK 59.07 0.00070812 34331000.0 129860.0 115645.0 156995.0 187809.0 180039.0 186568.0 144976.0 153326.0 134582.0 158015.0 True False 171152.778744202 153024.98468876776 154913.14372128926 144512.53667012497 155043.6925493537 174901.87346677517 157878.58314427358 129632.98978096948 141695.72976540157 152482.9429460225 1.1224388475030183 1.003554769682909 1.0159375253934273 0.9477291943485182 1.0167936790427614 1.1470258252340313 1.0353852050203483 0.8501474806061313 0.9292562632107678 1.0 17.218288343318946 -7.737314280517134 23.797425746445274 0.9172764658129867 1.0383706989554762 0.40159993878722944 0.06385307534984806 124.65947582205612 122966.44151827712 0.03107127533303925 0.01792399123146165 1.8309889337098302e-08 7.737314280517134 0.12109423314248946 AAPT(ph)TPPPPVK ddPTM_PC-9_AZD4547_30min_R2 1 AAPTTPPPPVK 11 0 C9JC20;C9JMQ4;C9JSC3;Q9NZQ3-5;Q9NZQ3-4;Q9NZQ3-3;Q9NZQ3-2;Q9NZQ3 C9JC20 NCKIPSD NCK-interacting protein with SH3 domain 1 AAPT(0.964)T(0.036)PPPPVK 107.57 0.0056056000000000005 4202700.0 29100.0 31648.0 48507.0 68176.0 52404.0 53327.0 43245.0 61551.0 49369.0 47614.0 True False 38353.19468239854 41877.597089628725 47863.76548608924 52459.07650870009 45128.609158884035 49992.45425990908 47093.721223334345 52039.70725127147 51978.54455118893 45947.04835257365 0.8347259738666162 0.9114317152275359 1.0417157837606392 1.1417289769335461 0.9821873390558336 1.0880449572362756 1.024956398982623 1.132601747384205 1.1312705911451095 1.0 15.48768456502721 -5.168075034323604 2.511001412798775 1.0735168518821034 0.8412829131491067 0.69346582314415 0.053151401269125334 0.16753453590722983 1.9479322634012057 0.01424143084435977 0.0565304068675096 6.79086294762396e-06 5.168075034323604 -0.2322339387329967 AAPT(ph)TPPPPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAPTTPPPPVK 11 0 C9JC20;C9JMQ4;C9JSC3;Q9NZQ3-5;Q9NZQ3-4;Q9NZQ3-3;Q9NZQ3-2;Q9NZQ3 C9JC20 NCKIPSD NCK-interacting protein with SH3 domain 1 AAPT(0.925)T(0.075)PPPPVK 113.44 0.0038201999999999997 26674000.0 42545.0 65542.0 66195.0 73174.0 85849.0 63040.0 78012.0 60981.0 65453.0 52775.0 True False 49747.02819794698 72048.57660801204 67773.33984593546 69074.29801330878 69027.50472220295 59734.0714244225 70622.1386020305 59380.31336471036 66410.12630008956 62342.68973332983 0.7979608902140627 1.1556860462100533 1.0871096536873077 1.1079775080089314 1.1072269261635541 0.9581567891910717 1.1328054484674295 0.9524823779453372 1.0652431998708771 1.0 15.927932779960678 -9.728707185492446 12.867283343602368 1.0000005567197565 1.0469232726160564 0.010220720407914108 0.10358602382322947 0.0 0.0 0.09474664139719723 0.022979435891362535 1.8676384849219442e-10 9.728707185492446 0.04692271589629993 AAPT(ph)TPPPPVK ddPTM_PC-9_Lapatinib_30min_R1 1 AAPTTPPPPVK 11 0 C9JC20;C9JMQ4;C9JSC3;Q9NZQ3-5;Q9NZQ3-4;Q9NZQ3-3;Q9NZQ3-2;Q9NZQ3 C9JC20 NCKIPSD NCK-interacting protein with SH3 domain 1 AAPT(0.763)T(0.237)PPPPVK 89.561 0.022533 4463800.0 49290.0 59578.0 67365.0 65655.0 69821.0 59572.0 59061.0 64020.0 74316.0 51350.0 True False 48587.11556132104 59440.05080146138 61826.509736419954 70483.4877186594 65714.26605336757 57024.24442911462 62118.88959230754 66994.60291650046 65945.74949782655 60225.77908042594 0.8067494734511853 0.9869536220043696 1.0265788285421162 1.170320895717019 1.091131855108296 0.9468411251760483 1.0314335578681935 1.1123908057218386 1.094975449130548 1.0 15.878093530830913 -4.73175007135727 1.8752783899363554 1.063581451542134 0.7042554125964765 0.6239717543670995 0.0594067445278199 0.6636286786299429 2.219693870168368 0.017288471728247514 0.4403932092805263 1.8545986044241835e-05 4.73175007135727 -0.3593260389456575 AAPTT(ph)PPPPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AAPTTPPPPVK 11 0 C9JC20;C9JMQ4;C9JSC3;Q9NZQ3-5;Q9NZQ3-4;Q9NZQ3-3;Q9NZQ3-2;Q9NZQ3 C9JC20 NCKIPSD NCK-interacting protein with SH3 domain 1 AAPT(0.038)T(0.962)PPPPVK;AAPT(0.009)T(0.991)PPPPVK 96.229 0.014403999999999998 28797000.0 70357.0 95172.0 137459.0 105044.0 140001.0 109578.0 103483.0 101519.0 91547.0 71060.0 True False 82267.05048590805 104620.0471901639 140736.54387616058 99158.72523724282 112568.80905558755 103831.53677895575 93680.3410879598 98854.23381827178 92885.70168509148 83942.6154893495 0.980039161352388 1.2463281800343464 1.6765804002618552 1.1812679967045334 1.3410209867700644 1.2369347342069623 1.116004553132441 1.177640620821664 1.1065380932391446 1.0 16.357115795057382 -7.155940094807831 2.4531694778235775 1.109828370798931 1.2997017463526015 0.2117902333965821 0.16731458480248237 0.5133831543801807 6.033861281020276 0.0773125248978425 0.05537689047072098 6.983287226651647e-08 7.155940094807831 0.18987337555367056 AAPTT(ph)PPPPVK ddPTM_PC-9_Lapatinib_30min_R1 1 AAPTTPPPPVK 11 0 C9JC20;C9JMQ4;C9JSC3;Q9NZQ3-5;Q9NZQ3-4;Q9NZQ3-3;Q9NZQ3-2;Q9NZQ3 C9JC20 NCKIPSD NCK-interacting protein with SH3 domain 1 AAPT(0.009)T(0.991)PPPPVK 106.29 0.0059960000000000005 6234200.0 84986.0 113780.0 150940.0 108690.0 131700.0 117360.0 104030.0 109360.0 126800.0 86727.0 True False 83774.0840554763 113516.54940062213 138530.29584524958 116683.42517921135 123953.66493216236 112340.78637952216 109416.16437730058 114441.26483830798 112518.44873680508 101717.64639353647 0.8235944010281349 1.1159966183393268 1.3619101577447856 1.1471306043375562 1.2186053190082349 1.1044375323519158 1.0756851761392436 1.1250876214294712 1.1061841551217304 1.0 16.634210459984303 -6.9833269737909 24.41392563643651 1.0875772028863044 1.1474895840115267 0.03312130577985317 0.12903413984597456 716.0403611521621 1048476.9428955268 0.047420484889768515 0.04180996705250672 1.0391375202172422e-07 6.9833269737909 0.059912381125222236 AAPWGSNPS(ph)PSAESTQAMDR ddPTM_PC-9_AZD4547_30min_R2 1 AAPWGSNPSPSAESTQAMDR 20 0 Q96N67-2;Q96N67-6;Q96N67;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 AAPWGS(0.388)NPS(0.541)PS(0.065)AES(0.001)T(0.005)QAMDR 95.365 0.001972 0.0 3011.5 5669.1 5508.8 8685.8 7728.7 5473.1 5081.8 6037.6 6181.2 6240.0 True False 3969.094356908702 7501.52570970723 5435.749712614021 6683.423004272278 6655.703412072871 5130.866191796054 5534.07035524894 5104.627650245755 6507.925612830092 6021.539499308179 0.6591494346860493 1.2457820314172294 0.9027176045658323 1.109919316321041 1.1053159101318777 0.8520854496405023 0.9190457616170674 0.8477280022546113 1.0807743789736486 1.0 12.555916666011376 -6.765409811258541 24.978952478309505 0.9291046741344281 1.01817065337419 0.03442658082917438 0.15834452273384475 295.8514114637553 1861259.829276926 0.05167264168304969 0.0472617264263519 1.716288089946164e-07 6.765409811258541 0.089065979239762 AAQASDLEK ddPTM_PC-9_Lapatinib_30min_R1 2 AAQASDLEK 9 0 P37837 P37837 TALDO1 Transaldolase 0 ; 127.4 0.0062826 21844000.0 112704.0 101408.0 101113.0 101824.0 107020.0 97765.0 115692.0 92592.0 81226.0 102777.0 False True 111096.8202926178 101173.19600648878 92799.87944746712 109312.47663490674 100725.29400941543 93583.81885134621 121681.96567469632 96894.16234371476 72077.47253230069 120541.86750825595 0.921645089703034 0.8393199649039733 0.7698559958108433 0.9068424016860357 0.8356042269091005 0.7763594573888332 1.0094581093690314 0.8038216459279466 0.5979455439195355 1.0 16.879174795627932 -7.992560692194635 24.936909052626905 0.7662763478337663 0.861375623329819 0.04944896063186832 0.11284691929585478 344.22276145703955 1153850.9522922018 0.05829871484132363 0.02791621181561319 1.017277192834491e-08 7.992560692194635 0.09509927549605268 AAQDRDQIYR ddPTM_PC-9_AZD4547_30min_R2 2 AAQDRDQIYR 10 1 P62995;H7C2L4;P62995-3 P62995 TRA2B Transformer-2 protein homolog beta 0 ; 105.2 0.0032347 39897000.0 77545.0 63319.0 114107.0 170667.0 128527.0 95250.0 82088.0 127137.0 89491.0 106815.0 False True 102202.69696380036 83785.6284794681 112593.86662381078 131322.35992886525 110683.24458751008 89294.00244259636 89393.67297447259 107490.89796761882 94221.3115605025 103075.4393619557 0.9915329742608164 0.8128573498993271 1.092344280274475 1.2740412336998999 1.0738081280336735 0.8662975680271905 0.86726453486714 1.0428371553203666 0.9141005087510576 1.0 16.653341085204033 -6.746255009588472 24.96181311617333 0.9363500548249674 1.0507219488725188 0.18206214720058067 0.11738221206520787 466.8588690992411 767475.140811186 0.04330571634355384 0.04314445879115139 1.793680102184917e-07 6.746255009588472 0.11437189404755144 AAQDRDQIYR ddPTM_PC-9_Lapatinib_30min_R1 2 AAQDRDQIYR 10 1 P62995;H7C2L4;P62995-3 P62995 TRA2B Transformer-2 protein homolog beta 0 ; 122.94 0.00064405 32427000.0 124918.0 116091.0 125776.0 111759.0 117154.0 130154.0 99023.0 90781.0 137759.0 88189.0 False True 123136.6464128442 115822.19842210975 115435.18278940047 119978.12967709504 110263.23205362607 124587.61682379287 104149.92641673984 94999.01667233411 122243.13075341916 103432.35114554416 1.1905041802595522 1.1197869635500337 1.1160452364363893 1.1599671509764735 1.066042015215045 1.2045323870524822 1.00693762892604 0.9184652153817606 1.1818655323942655 1.0 16.658327970896366 -7.27867532517248 24.742814887021385 1.0200225154367282 1.1378397809177372 0.38642170781383556 0.071236266206284 742.4512295301486 1065810.8144236733 0.028300217815944294 0.01913355651386705 5.2641065941503914e-08 7.27867532517248 0.11781726548100901 AAQEEYVK ddPTM_PC-9_AZD4547_30min_R2 2 AAQEEYVK 8 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BR68 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ; 121.96 0.015433 10849900.0 52412.0 51639.0 57787.0 61419.0 67499.0 59007.0 47085.0 55631.0 53190.0 62921.0 False True 69077.92576267594 68330.29689431685 57020.70662264494 47259.798464090745 58127.92896755045 55317.28296199778 51275.473784268615 47034.50722320486 56001.51481046283 60718.15494166184 1.1376815687012587 1.1253684661526486 0.9391047319772904 0.7783470777314969 0.957340173188726 0.9110501301488289 0.8444833976515627 0.774636634930619 0.9223191130275488 1.0 15.88984033142013 -5.326360359749118 3.5451608398170955 0.8762049642499148 1.1370561522347802 0.6686114531612167 0.06837624331698716 0.12438101914293316 3.0731126785995033 0.01803889324749163 0.04431391977841375 4.716715051756969e-06 5.326360359749118 0.2608511879848654 AAQEEYVK ddPTM_PC-9_Lapatinib_30min_R1 4 AAQEEYVK 8 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BR68 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ;;; 132.9 0.016161000000000002 55802900.0 228329.0 221127.0 227929.0 230027.0 234201.0 188784.0 227280.0 211849.0 209711.0 207584.0 False True 225072.9865895901 220614.99401750191 209189.5574513837 246943.95292757777 220425.75763688202 180710.1483969982 239047.44631041898 221692.27793279698 186091.1388252693 243464.61781170667 0.9244587103151863 0.9061480719474546 0.8592195421725263 1.0142909271463914 0.9053708075452561 0.7422439860922945 0.9818570289966985 0.9105728788248475 0.7643457209424595 1.0 17.893352598216346 -6.531011029977412 24.999563122113404 0.8742835460191923 0.9248363349180471 0.061112548198645866 0.08418518208062896 549.1273669363247 1688067.4159401823 0.027255990683740166 0.027304589808793838 2.944346853913099e-07 6.531011029977412 0.05055278889885473 AAQEEYVKR ddPTM_PC-9_AZD4547_30min_R2 1 AAQEEYVKR 9 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BR68 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 86.882 0.0071631 55197000.0 37301.0 38799.0 54854.0 77712.0 65238.0 55996.0 49265.0 60517.0 52695.0 49546.0 False True 49161.94209100166 51340.017994202 54126.60011903312 59796.69903843136 56180.829789849566 52494.561267985584 53649.48956104906 51165.48819231524 55480.35012102535 47811.409620628714 1.0282470749364865 1.0738026425401779 1.1320854279033776 1.250678436651478 1.1750506884367153 1.0979505035412358 1.1221064174167632 1.070152262782049 1.1603997991535433 1.0 15.5450673207446 -13.190132517245607 0.5391775928216342 0.003083694720668582 1.1258339280420682 0.27694032654226286 0.05953053479388088 1187.9511841878873 21.488985915920296 1388.6660800829925 0.0287327826671106 6.454572491711473e-14 13.190132517245607 1.1227502333213997 AAQEEYVKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AAQEEYVKR 9 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BR68 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ; 76.282 0.015656 49663300.0 65158.0 50873.0 73000.0 74016.0 78748.0 78502.0 68414.0 69834.0 65332.0 58534.0 False True 76187.96247083863 55923.33523205578 74740.5968540416 69869.12348310961 63317.89469724802 74385.21692512708 61933.33064553281 68000.93149523929 66287.35690399892 69145.75084511092 1.1018459057810006 0.808774719321888 1.0809138080149474 1.0104615631352254 0.9157163516682679 1.0757742307513989 0.8956925029893131 0.983443388264941 0.9586613218285112 1.0 16.07735297694054 AAQEEYVKR ddPTM_PC-9_Lapatinib_30min_R1 1 AAQEEYVKR 9 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BR68 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 91.265 0.0050207 57956000.0 55436.0 42003.0 46814.0 43061.0 41103.0 45161.0 38118.0 31172.0 42500.0 29311.0 False True 54645.472474282666 41905.74463415663 42965.133627265845 46227.84958728501 38685.40235160719 43229.569305432866 40091.56352719359 32620.364918980787 37713.20245515947 34377.367295547505 1.5895770029300718 1.2189922594678793 1.2498087261275128 1.3447175634439104 1.125316026065139 1.25750087066824 1.1662197160858847 0.948890723322077 1.0970357948278378 1.0 15.069171443414538 -1.5228787452810482 0.19773045091310304 0.9683416469546263 3.338373821396879 0.6836779036994145 0.09729099177557318 32.46667485119073 0.3894369779501362 0.18536282203315776 23.755930577672718 0.029999999999950913 1.5228787452810482 2.370032174442253 AAQGDVELLS(ph)HLPDQR ddPTM_PC-9_Lapatinib_30min_R1 1 AAQGDVELLSHLPDQR 16 0 H0YG18;Q96KJ4 H0YG18 MSLNL Mesothelin-like protein 1 AAQGDVELLS(1)HLPDQR 66.387 0.015191999999999999 705760.0 3208.7 4509.6 5266.5 4604.1 5416.3 6121.7 4553.3 3849.0 5787.6 4647.0 True False 3162.9433495964845 4499.158298268997 4833.508699277898 4942.700872827358 5097.723882855512 5859.889161379689 4789.047594531992 4027.8385914653268 5135.739541870138 5450.22775826172 0.580332325525652 0.8254991346827579 0.886845268429568 0.9068796923825746 0.935323092714453 1.0751640887845437 0.8786876084715031 0.7390220684557143 0.9422981515011248 1.0 12.412100804248718 -4.457230297775617 1.4073182477558452 0.9184562779554127 0.15847642747465188 0.6156975995242482 0.08148085788201118 1.9881350215556801 1.9768271037708256 0.024984959492537838 2.6639890683880996 3.489552223534574e-05 4.457230297775617 -0.7599798504807609 AAQMHSGYQR ddPTM_PC-9_AZD4547_30min_R2 1 AAQMHSGYQR 10 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 0 67.207 0.02999 1914300.0 5376.7 5133.4 7286.0 9409.1 7819.6 6874.6 5304.7 7726.7 6466.0 6895.0 False True 7086.37875769252 6792.6711608916885 7189.382879412172 7239.977364145887 6733.983516121088 6444.730175242765 5776.808023434425 6532.716056902389 6807.779559399373 6653.608148674664 1.065042996122947 1.0209003910524435 1.0805239381048053 1.0881280054924818 1.012079967087096 0.9686068117080946 0.8682218571265142 0.9818305964116093 1.0231710986399791 1.0 12.699921188663108 -6.564591831909549 3.272785730866096 0.9612056932497341 1.0613904037692208 0.5336062941621447 0.04159974862215813 0.19772808396166314 4.375249707203731 0.015133475120192691 0.015655662143611984 2.7252614193299196e-07 6.564591831909549 0.10018471051948663 AAQMHSGYQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAQMHSGYQR 10 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 0 72.848 0.020012000000000002 1334300.0 1183.1 892.38 2870.7 3134.3 2959.5 1991.7 3245.1 2175.8 3551.1 833.77 False True 1383.3754627098615 980.9695888660376 2939.1483751903747 2958.695332537703 2379.6072199485106 1887.2517458125355 2937.7006355105495 2118.687555450662 3603.028119478833 984.9259008803112 1.404547754783809 0.9959831374007552 2.984131468736288 3.0039775884594646 2.416026645072137 1.9161357662802243 2.9826615716825793 2.151113655917681 3.6581717632346793 1.0 9.943871379872963 -5.2559062668557175 24.985782005350828 2.564520385460393 1.2002653184530618 0.3594575163778525 0.6989031864878021 430.3043103491157 1943102.9662662095 0.16742214899605382 0.41729556697435044 5.547454299349033e-06 5.2559062668557175 -1.364255067007331 AAQMHSGYQR ddPTM_PC-9_Lapatinib_30min_R1 4 AAQMHSGYQR 10 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 0 ;;; 75.387 0.016676 5937840.0 16648.2 13278.82 18619.9 17547.99 17873.949999999997 14343.3 15892.22 16457.9 16380.54 15878.5 False True 16410.79361509403 13248.073708138269 17089.04369689253 18838.52772297861 16822.63940253776 13729.87049486536 16715.04139037033 17222.59411651785 14535.59109046677 18623.077568228684 0.8812073920097475 0.7113793979325806 0.9176272629636015 1.0115689876692286 0.9033222001522184 0.7372503521270176 0.8975445293148808 0.9247984954914172 0.7805149840144981 1.0 14.184803885611272 -11.768596035458714 2.2547758597204877 1.4847052271412178 0.8646803551370641 0.17879646929820847 0.08812697049149515 5332024.734467228 1128042.1838165494 13131374.407637047 0.025384067687261987 1.7037425293859194e-12 11.768596035458714 -0.6200248720041537 AAQPPAQPCQLCGRS(ph)PLGEAPPGTPPCR ddPTM_PC-9_AZD4547_30min_R2 2 AAQPPAQPCQLCGRSPLGEAPPGTPPCR 28 1 M0QXZ5;Q96B54 M0QXZ5 ZNF428 Zinc finger protein 428 1 AAQPPAQPCQLCGRS(1)PLGEAPPGTPPCR;AAQPPAQPCQLCGRS(0.997)PLGEAPPGT(0.003)PPCR 85.387 2.1371e-07 23011000.0 23435.0 8743.8 25907.0 55062.0 41757.0 29563.0 22176.5 29625.0 13716.4 29761.0 True False 30886.842521718554 11570.062355671633 25563.4562526669 42368.30659941978 35959.76132828641 27714.420936592924 24150.165538426947 25047.13696477581 14441.42090141441 28719.076448543397 1.0754817473695295 0.4028702794953023 0.890121111605713 1.4752670294022863 1.2521210907570899 0.9650178335730769 0.8409102424201326 0.8721428423944384 0.5028511598306242 1.0 14.809721735098645 -7.4399519504982505 2.311062023574378 0.767138541704066 1.0093194441007378 0.11529600503762838 0.28241305100019165 0.7713533824013081 8.082665975302548 0.16630550631335203 0.09478191850820147 3.631182272463146e-08 7.4399519504982505 0.24218090239667178 AAQPPAQPCQLCGRS(ph)PLGEAPPGTPPCR ddPTM_PC-9_Lapatinib_30min_R1 1 AAQPPAQPCQLCGRSPLGEAPPGTPPCR 28 1 M0QXZ5;Q96B54 M0QXZ5 ZNF428 Zinc finger protein 428 1 AAQPPAQPCQLCGRS(0.995)PLGEAPPGT(0.005)PPCR 61.903999999999996 0.00050051 11539000.0 16877.0 10657.0 21308.0 14794.0 11125.0 15485.0 5830.5 7864.3 17183.0 8775.9 True False 16636.330885137253 10632.324371264132 19556.138491258604 15882.000111337278 10470.649372591544 14822.742647298062 6132.374761144398 8229.704088038645 15247.669594988358 10292.802621848297 1.6163071902130615 1.0329863266487924 1.899981881489424 1.543019981518437 1.0172787487798256 1.4401075384302195 0.5957925150655611 0.799559108475435 1.4813914300292204 1.0 13.3293482459518 -6.526627596553353 1.696311282342852 0.9959999254199093 1.507347607009736 0.31484307660425115 0.3233811646563358 0.4494297919290164 2.6238792885906306 0.12677620209313953 0.13829790227479677 2.97421530033112e-07 6.526627596553353 0.5113476815898267 AAQQAASSSGQGQQAQT(ph)PTGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAQQAASSSGQGQQAQTPTGK 21 0 U3KPX3;A0A590UJ43;P48729;P48729-2;H0Y9X2;U3KQK7 U3KPX3 CSNK1A1 Casein kinase I isoform alpha 1 AAQQAAS(0.001)SS(0.001)GQGQQAQT(0.998)PTGK 241.08 8.614799999999997e-126 0.0 8220.7 9283.7 8341.3 7931.7 9057.7 8241.7 11489.0 8217.1 7907.4 6741.4 True False 9612.302143773948 10205.324382164137 8540.188226556407 7487.312563918355 7282.908706243493 7809.490743316348 10400.678746843148 8001.409831737119 8023.030765668926 7963.562455106966 1.2070354439939954 1.2815023979148363 1.072408017730765 0.9401963764491863 0.9145289871586333 0.9806529159959293 1.3060334247988825 1.004752568570098 1.0074675512243674 1.0 12.959198241382436 -5.361422371720942 4.670587325637224 1.0266405444711304 1.2432979794873693 0.42015280928155097 0.1025251640836462 0.21962512878119983 7.755496616303023 0.02937130057252389 0.06440463780751944 4.350885238912283e-06 5.361422371720942 0.2166574350162389 AAQQQQPSAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 AAQQQQPSASPR 12 0 Q86U86-8;Q86U86 Q86U86-8 PBRM1 Protein polybromo-1 1 AAQQQQPS(0.001)AS(0.999)PR;AAQQQQPSAS(1)PR 164.22 0.00020102 51560000.0 11619.900000000001 10475.8 14091.0 19319.1 16698.8 16063.6 12606.7 18398.5 12913.3 12529.2 True False 15314.786491065397 13861.897484565623 13904.144133104168 14865.379972119621 14380.459862269525 15059.14055261829 13728.67187758606 15555.434580470152 13595.87067497555 12090.55652159167 1.2666734127346249 1.1465061562559704 1.150000341859677 1.2295033686474721 1.18939602462372 1.2455291471261256 1.135487175720075 1.286577218566474 1.1245032973209832 1.0 13.561593032115134 -8.532253849507464 22.101624585875875 0.9999999973756168 1.201766301652774 0.6257742883387363 0.049365677122021646 155.77833145730898 367245.72098539124 0.04466799368889756 0.011533226385402894 2.9359330678231795e-09 8.532253849507464 0.20176630427715714 AAQQQQPSAS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AAQQQQPSASPR 12 0 Q86U86-8;Q86U86 Q86U86-8 PBRM1 Protein polybromo-1 1 AAQQQQPS(0.003)AS(0.997)PR;AAQQQQPS(0.114)AS(0.886)PR;AAQQQQPSAS(1)PR 181.76 0.00064243 28441300.0 35007.9 33511.5 37151.8 43525.8 40971.3 41169.5 34518.2 34186.1 36104.9 33654.8 True False 40934.04603245758 36838.30025021205 38037.6398109861 41087.19053854753 32943.26787993797 39010.49894523731 31248.386205873543 33288.75109816701 36632.86585873988 39756.14882874978 1.0296280509659428 0.9266063573937605 0.9567737552959119 1.0334801470718715 0.8286332768760275 0.9812444136195293 0.7860013388237489 0.8373233343490795 0.9214389959283158 1.0 15.278890389599468 -6.260895640647782 24.99999291816084 0.8834246585782904 0.9802032169503677 0.30098713558654755 0.06922799289449917 60.17074103171851 2766531.7145247683 0.020395534028863866 0.024747056710597907 5.48408729671378e-07 6.260895640647782 0.09677855837207727 AAQQQQPSAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 AAQQQQPSASPR 12 0 Q86U86-8;Q86U86 Q86U86-8 PBRM1 Protein polybromo-1 1 AAQQQQPSAS(1)PR;AAQQQQPS(0.041)AS(0.959)PR 180.61 0.00071569 43370000.0 12902.5 8931.9 9763.1 9543.599999999999 9522.900000000001 10992.5 11178.3 8917.7 11562.900000000001 8821.6 True False 12718.50798397128 8911.2187343243 8960.415604655856 10245.468180516313 8962.781744741755 10522.376399769053 11757.057678158031 9332.048897664408 10260.564439265012 10346.401805956872 1.2292687083396165 0.8612867450395871 0.8660417189188377 0.9902445674028968 0.8662704109926886 1.0170082891726537 1.1363426530940433 0.9019608046047026 0.9917036503799379 1.0 13.336841504833673 AAS(ph)AIYR ddPTM_PC-9_AZD4547_30min_R2 1 AASAIYR 7 0 Q9UKM9-2;Q5QPL9 Q9UKM9-2 RALY RNA-binding protein Raly 1 AAS(0.999)AIY(0.001)R 70.816 0.043012 11090000.0 25858.0 28489.0 33286.0 50227.0 40435.0 30388.0 29779.0 40997.0 28071.0 36312.0 True False 34080.30612018769 37697.512117240694 32844.60589131395 38647.94114941444 34821.298208905326 28487.833556174493 32429.27331043296 34661.8556673389 29554.77575191768 35040.727932512615 0.9725912711010266 1.075819891351714 0.9373265862105282 1.102943444093091 0.9937378662900525 0.8129920591558829 0.92547373367616 0.989187659973748 0.8434406901831288 1.0 15.096745125199659 -6.540394258132476 24.739526411805436 0.9130373974515895 1.023491971596505 0.3608274209140989 0.06887299411071623 222.28600357543243 313962.1602219697 0.021614679078079905 0.0216192306397501 2.881414530168637e-07 6.540394258132476 0.11045457414491544 AAS(ph)AIYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AASAIYR 7 0 Q9UKM9-2;Q5QPL9 Q9UKM9-2 RALY RNA-binding protein Raly 1 AAS(1)AIYR;AAS(1)AIYR 82.426 0.022498 15638000.0 73963.0 84433.0 71698.0 96795.0 98626.0 95035.0 89675.0 98698.0 81363.0 59051.0 True False 86483.47506416147 92814.95024174264 73407.55223617915 91371.88996362386 79300.94329266502 90051.19730044401 81180.3348092225 96107.28207917506 82552.7799513268 69756.4788525411 1.2397912923182337 1.330556699083752 1.0523402763972087 1.3098695843976844 1.1368254905798794 1.290936681176298 1.1637676692487648 1.377754205202031 1.1834424745812633 1.0 16.09003959755725 -8.546506936572493 22.985830096714807 0.9999999963614981 1.2359693363713942 0.3710148414780653 0.0929027425728418 2225.653374343719 2165144.0707146022 0.0835148270460161 0.021563435580286366 2.8411428057503855e-09 8.546506936572493 0.2359693400098961 AAS(ph)AIYR ddPTM_PC-9_Lapatinib_30min_R1 2 AASAIYR 7 0 Q9UKM9-2;Q5QPL9 Q9UKM9-2 RALY RNA-binding protein Raly 1 AAS(1)AIYR;AAS(1)AIYR 90.601 0.015819 21313000.0 76586.0 81901.0 95187.0 63983.0 85642.0 84464.0 84793.0 84432.0 82254.0 76779.0 True False 75493.86959584785 81711.36326648231 87361.09229244555 68688.52326103096 80604.70593865024 80851.67161520068 89183.16664466467 88355.01895417018 72989.68834698084 90050.14784841321 0.8383536440487714 0.907398435414364 0.9701382438539212 0.7627807938378786 0.8951090904851923 0.8978516254221274 0.9903722400855135 0.9811757233636469 0.8105449029339601 1.0 16.458441024365037 -7.046335903173344 5.562806299681671 0.9444214628853655 0.8773233709101037 0.18521443128744353 0.06997888690948965 0.38721298340312754 28.98555489992497 0.026766044902704615 0.021103049683260683 8.988021380262833e-08 7.046335903173344 -0.06709809197526184 AAS(ph)DDGSLK ddPTM_PC-9_Lapatinib_30min_R1 2 AASDDGSLK 9 0 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614;Q92614-5;Q92614-2;A0A1B0GV45 A0A0D9SFK2;A0A1B0GV45 MYO18A Unconventional myosin-XVIIIa 1 AAS(1)DDGSLK;AAS(1)DDGSLK 108.47 0.0024334 16017500.0 54625.0 95783.0 63487.0 69913.0 97251.0 74491.0 90225.0 92106.0 106768.0 83748.0 True False 53846.037483001885 95561.22034839001 58267.34392690704 75054.63524293125 91530.88738282243 71305.19357700215 94896.40902568445 96385.58100948438 94742.66352311692 98223.73021280445 0.5481978475704694 0.9728934152811541 0.5932104573983212 0.7641191703911396 0.9318612435560959 0.7259467078120273 0.9661250781261181 0.9812860985900487 0.9645598198913267 1.0 16.58378399191495 -7.023105766070666 0.6610987510709446 1.010424530877488 0.7167837530562533 0.44323824067429773 0.12207740202082441 0.7312948455059396 0.6700909603178046 0.09720910205719727 0.0803102780799018 9.48187517975078e-08 7.023105766070666 -0.29364077782123466 AAS(ph)DPLLSSVSPAVSK ddPTM_PC-9_AZD4547_30min_R2 1 AASDPLLSSVSPAVSK 16 0 P19532 P19532 TFE3 Transcription factor E3 1 AAS(1)DPLLSSVSPAVSK 107.69 0.0045215 0.0 7926.1 9917.5 11178.0 10690.0 17149.0 13982.0 8889.9 9282.3 9346.1 9262.9 True False 10446.434926878326 13123.137927717169 11029.77241642455 8225.58565885361 14768.157363287191 13107.70332968381 9681.083877981735 7847.933821034212 9840.115765558692 8938.608690407325 1.1686869051655835 1.4681410029505562 1.2339473399547523 0.920231094541714 1.652176292171284 1.4664142691189341 1.0830638428518762 0.8779815844781754 1.1008554134514066 1.0 13.125834575616945 -7.447620675674186 5.7577520167673395 0.9893757682172218 1.3170779060539903 0.37949058996744467 0.19212421459204337 0.24546951805177247 14.264379667647969 0.08585448133411779 0.05660358514313961 3.567626033089193e-08 7.447620675674186 0.3277021378367685 AAS(ph)DSNPAGPLR ddPTM_PC-9_AZD4547_30min_R2 1 AASDSNPAGPLR 12 0 Q9BUU2-2;Q9BUU2 Q9BUU2-2 METTL22 Methyltransferase-like protein 22 1 AAS(0.982)DS(0.018)NPAGPLR 86.738 0.0089588 4630200.0 16529.0 13236.0 27848.0 35448.0 33938.0 26505.0 19761.0 31691.0 22294.0 21821.0 True False 21784.878175442107 17514.278155912725 27478.71732444005 27276.011266140573 29226.294512522065 24847.638160010687 21519.69071787051 26793.88413673286 23472.415325896945 21057.053431795488 1.0345644154821598 0.8317535125530297 1.3049649806628716 1.2953384648278783 1.387957465520379 1.1800149646052347 1.0219706564156055 1.2724422352595135 1.1147055974343656 1.0 14.362015949970576 -5.262291136853482 24.999995652953498 1.2103538189795302 0.9331589570372043 0.4047949857539105 0.1272571510374754 67.23823601448885 1973585.5568992002 0.03342368832321549 0.07683174934818605 5.466493841216918e-06 5.262291136853482 -0.2771948619423259 AAS(ph)DSNPAGPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AASDSNPAGPLR 12 0 Q9BUU2-2;Q9BUU2 Q9BUU2-2 METTL22 Methyltransferase-like protein 22 1 AAS(0.998)DS(0.002)NPAGPLR 70.68 0.029199 4090300.0 17082.0 18070.0 16493.0 22956.0 27631.0 21070.0 24308.0 21972.0 17369.0 15933.0 True False 19973.645215121174 19863.870179530346 16886.255670050814 21669.84974435615 22216.903900793153 19965.05210838487 22005.370265320144 21395.258281258346 17622.988766080314 18821.5267744414 1.061212804597993 1.0553803853205144 0.8971777833125324 1.1513332581383682 1.1803986024642001 1.060756247229439 1.169159682369776 1.136744034512223 0.9363208934788099 1.0 14.20009604165278 -5.790535098318644 24.999996825534208 1.1021331897418645 1.009669055664271 0.16967600491678614 0.08442402935554064 324.26331239081196 278616.42706150375 0.02365867626517253 0.035097479882473734 1.6198130803981628e-06 5.790535098318644 -0.09246413407759357 AAS(ph)DSNPAGPLR ddPTM_PC-9_Lapatinib_30min_R1 2 AASDSNPAGPLR 12 0 Q9BUU2-2;Q9BUU2 Q9BUU2-2 METTL22 Methyltransferase-like protein 22 1 AAS(0.993)DS(0.007)NPAGPLR;AAS(0.911)DS(0.089)NPAGPLR 99.834 0.0032219 7953500.0 34820.0 36043.0 43320.0 35492.0 45929.0 44624.0 36703.0 33096.0 41295.0 41521.0 True False 34323.46041479406 35959.54464797533 39758.396820035814 38102.20007784122 43227.54651988827 42715.5355436247 38603.30175084177 34633.76098288813 36643.922244372 48697.84952674519 0.704824971705237 0.738421614043267 0.8164302367848961 0.7824205883447735 0.8876684892655764 0.8771544525834768 0.7927106048007433 0.7111969279848187 0.7524751626711341 1.0 15.571570444555194 -11.985714093378038 2.241062005364035 3.3087514894803594 0.7881150594084753 0.5409146983245476 0.05940326291316976 2604958.1245434517 244159.3538355327 30758438.16554119 0.01728986859851957 1.0334415215612987e-12 11.985714093378038 -2.520636430071884 AAS(ph)EELLEK ddPTM_PC-9_AZD4547_30min_R2 3 AASEELLEK 9 0 Q6ZV73-2;Q6ZV73;F8VY01 Q6ZV73-2 FGD6 FYVE, RhoGEF and PH domain-containing protein 6 1 AAS(1)EELLEK;AAS(1)EELLEK;AAS(1)EELLEK 141.89 0.0006925 25562300.0 59079.6 53626.2 69739.0 87519.0 106803.9 88407.4 83718.0 97201.2 82184.4 87112.7 True False 77865.68386798048 70959.8204325027 68814.2152933469 67342.84670507108 91976.02205450974 82879.27130229493 91168.73981674436 82180.98800136932 86528.49960122214 84062.91088804236 0.9262787006232089 0.8441275668767791 0.8186037643283118 0.8011005804302971 1.0941332043213006 0.9859195979149017 1.0845298937859262 0.9776129226695535 1.0293302799907027 1.0 16.359181793819886 -6.257262795069192 24.999998858060174 1.0281320067920787 0.8452187927600129 0.782284882274811 0.046787261147237406 159.96030297950867 957481.8216980617 0.013772988246520672 0.01714444245870544 5.530153739186799e-07 6.257262795069192 -0.18291321403206584 AAS(ph)EELLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AASEELLEK 9 0 Q6ZV73-2;Q6ZV73;F8VY01 Q6ZV73-2 FGD6 FYVE, RhoGEF and PH domain-containing protein 6 1 AAS(1)EELLEK;AAS(1)EELLEK;AAS(1)EELLEK 136.5 0.00099815 25028700.0 54042.8 51493.0 64673.2 73689.7 78338.5 63810.0 70861.6 61158.1 69394.3 60980.6 True False 63191.17864604559 56604.88473461851 66215.25436247695 69561.10501423078 62988.633282627554 60463.691268914925 64149.07625444343 59552.76467736331 70409.06035638232 72035.90005783603 0.8772178676925088 0.7857871518114121 0.9191979875216966 0.9656449764406596 0.8744061396061599 0.8393549774538802 0.8905153708489734 0.8267095244114353 0.9774162646659853 1.0 16.13642845176323 -8.377866541421612 5.529709962161287 0.9976580846205855 0.8739240044712568 0.4969324738390527 0.04696092119358064 0.20106157545204878 7.9172975511818 0.04758362560506552 0.012378651369031731 4.1892228004473296e-09 8.377866541421612 -0.12373408014932863 AAS(ph)EELLEK ddPTM_PC-9_Lapatinib_30min_R1 4 AASEELLEK 9 0 Q6ZV73-2;Q6ZV73;F8VY01 Q6ZV73-2 FGD6 FYVE, RhoGEF and PH domain-containing protein 6 1 AAS(1)EELLEK;AAS(1)EELLEK;AAS(1)EELLEK;AAS(1)EELLEK 168.22 0.00021395 27068300.0 100999.8 82317.0 89869.2 95866.9 108264.5 85019.4 71672.8 68051.6 91144.6 84584.6 True False 99559.52433090529 82126.40004404144 82480.50128114407 102917.27162860346 101896.5949661965 81383.31845190142 75383.6668862962 71213.52577057984 80878.93535281245 99204.93540810523 1.0035743072795862 0.8278459101474457 0.8314153014851442 1.0374208823908464 1.0271323150105227 0.8203555409527765 0.7598781913035468 0.7178425698038564 0.8152712868578158 1.0 16.59812427548095 -6.902634872106824 7.736710743994261 0.7984395216251704 0.9374007796239193 0.2694750269365602 0.09725880313567527 0.2983525929808559 20.803095966179068 0.03516182017047299 0.031010831830774136 1.2513106125397983e-07 6.902634872106824 0.13896125799874892 AAS(ph)ELLMKLSAES(ph)Y(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 AASELLMKLSAESYK 15 1 A0A494C0H4;H0Y9M2;Q17R98-2;Q17R98;A0A5F9ZGT0;H0Y9K9;G5E9Z1;A0A590UJE4;Q17R98-3 A0A494C0H4 ZNF827 Zinc finger protein 827 3 AAS(0.978)ELLMKLS(0.024)AES(0.999)Y(0.999)K 71.354 0.018831 0.0 8307.0 9060.9 7777.3 11237.0 9515.4 12517.0 10207.0 12951.0 10586.0 12688.0 True False 10948.453203666139 11989.65872944316 7674.167920402457 8646.483259919367 8194.350957759807 11734.310011275371 11115.403226420942 10949.720534373391 11145.554348252675 12243.79698192664 0.8942040789983214 0.9792435097659149 0.6267800692653168 0.7061929622553075 0.6692655039817863 0.9583881559451423 0.907839556865297 0.8943075869794749 0.9103021198983365 1.0 13.579763407965745 -6.77959197822075 24.999922983727934 0.9259162433402383 0.7744041453231179 0.38155810100857146 0.10095717004955436 309.23123794876653 425873.24724405335 0.03901707447582291 0.034475793581796095 1.6611468300762228e-07 6.77959197822075 -0.1515120980171204 AAS(ph)GGSGSENVGPPAAAVPGPLSR ddPTM_PC-9_AZD4547_30min_R2 3 AASGGSGSENVGPPAAAVPGPLSR 24 0 Q9UL54-2 Q9UL54-2 TAOK2 Serine/threonine-protein kinase TAO2 1 AAS(0.682)GGS(0.316)GS(0.002)ENVGPPAAAVPGPLSR;AAS(0.674)GGS(0.318)GS(0.009)ENVGPPAAAVPGPLSR;AAS(0.872)GGS(0.086)GS(0.041)ENVGPPAAAVPGPLSR 276.27 2.0567999999999998e-110 74368000.0 57541.0 57782.3 70742.0 115768.0 87542.0 78786.0 77298.0 91688.0 61574.0 83770.0 True False 75837.84107284856 76459.2984805376 69803.91485799836 89079.47619777033 75388.30438491402 73859.49896527472 84177.37225393207 77519.72638063689 64828.67593418759 80837.23779760337 0.9381547803838612 0.9458425419232278 0.8635118759595701 1.1019609108960835 0.9325937703817622 0.913681627150606 1.0413192551765755 0.95896060395739 0.8019655013015499 1.0 16.302732405327184 -10.53537522020025 22.44825822469879 0.9999999996680325 0.9485836231409579 0.04032924061062826 0.07909257006957346 0.0 0.0 0.07521154079720088 0.01824147805719478 2.9149075143474665e-11 10.53537522020025 -0.05141637652707465 AAS(ph)GGSGSENVGPPAAAVPGPLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AASGGSGSENVGPPAAAVPGPLSR 24 0 Q9UL54-2 Q9UL54-2 TAOK2 Serine/threonine-protein kinase TAO2 1 AAS(1)GGSGSENVGPPAAAVPGPLSR;AAS(0.941)GGS(0.052)GS(0.006)ENVGPPAAAVPGPLSR;AAS(0.939)GGS(0.043)GS(0.018)ENVGPPAAAVPGPLSR;AAS(0.928)GGS(0.044)GS(0.028)ENVGPPAAAVPGPLSR 232.44 2.948e-48 59449000.0 83075.0 66176.7 71165.3 72533.6 96303.7 77665.0 69246.8 82778.0 64761.4 61808.0 True False 97137.95669395785 72746.28542942595 72862.15064790334 68469.77754910408 77433.68130689497 73592.11067858136 62687.24180058298 80605.16521054096 65708.41295846821 73013.3011281412 1.330414529860483 0.9963429170495026 0.9979298226774792 0.9377712894933615 1.0605421219209885 1.0079274535118516 0.8585729015397402 1.1039791923539484 0.8999512683743387 1.0 16.15587168907073 -4.761091724802382 6.162811848997105 0.9853742196655741 1.3421703243131184 0.6994965769239441 0.06799964172305047 0.06805733963851701 10.615671222626005 0.01583400234452605 0.10236977495253285 1.7334378497999873e-05 4.761091724802382 0.3567961046475443 AAS(ph)GGSGSENVGPPAAAVPGPLSR ddPTM_PC-9_Lapatinib_30min_R1 4 AASGGSGSENVGPPAAAVPGPLSR 24 0 Q9UL54-2 Q9UL54-2 TAOK2 Serine/threonine-protein kinase TAO2 1 AAS(0.922)GGS(0.07)GS(0.008)ENVGPPAAAVPGPLSR;AAS(0.912)GGS(0.088)GSENVGPPAAAVPGPLSR;AAS(0.746)GGS(0.231)GS(0.023)ENVGPPAAAVPGPLSR;AAS(0.719)GGS(0.085)GS(0.196)ENVGPPAAAVPGPLSR 225.56 6.712799999999999e-47 89800000.0 112657.0 101226.2 113244.0 99008.5 93992.1 104488.6 103785.7 85473.1 100948.7 111397.0 True False 111050.49052123619 100991.81695321931 103933.51545448138 106289.91537267393 88463.66947357857 100019.86615282334 109159.21571866985 89444.49226089219 89578.79436906245 130651.82302282758 0.8499727592919494 0.77298436881033 0.7954999252962742 0.8135356469852156 0.6770947961294206 0.7655451247346758 0.8354970730075268 0.6846019457781648 0.6856298848077396 1.0 16.99536772957805 -1.5228993633242027 0.9475022477583096 0.7667843400408004 55.680361820177126 0.029030302058751345 0.09135327973680611 3703.628527361768 6.534546471724953 0.028070754750855582 440745.45416779805 0.029998575789793796 1.5228993633242027 54.913577480136325 AAS(ph)IFGGAKPVDTAAR ddPTM_PC-9_Lapatinib_30min_R1 1 AASIFGGAKPVDTAAR 16 1 E7EX17;P23588-2;P23588;F8VX11 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 AAS(1)IFGGAKPVDTAAR 67.252 0.011937999999999999 6843400.0 34312.0 26355.0 37803.0 28506.0 31595.0 25044.0 22846.0 21397.0 33602.0 23692.0 True False 33822.70458794983 26293.976616746386 34694.983263799935 30602.42633322837 29736.644218159963 23972.92650041542 24028.854093663478 22391.18273358886 29817.38891525336 27787.13063239436 1.2172075280244723 0.9462645483118991 1.248598990762737 1.1013165316735483 1.0701588664031705 0.8627348687981361 0.8647475844681326 0.8058112595290828 1.0730646970973 1.0 14.762129245532991 -6.641818399113863 4.409114868087152 0.9060378679456649 1.1199366467235023 0.47270518236810655 0.10362138120772262 0.18349080384110092 6.203186181484883 0.033978610661813624 0.033790959176336254 2.2812957998305087e-07 6.641818399113863 0.21389877877783747 AAS(ph)KDTISNNR ddPTM_PC-9_AZD4547_30min_R2 1 AASKDTISNNR 11 1 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 AAS(0.995)KDT(0.004)IS(0.001)NNR 110.15 0.0095188 2338100.0 8954.7 9148.9 8774.2 11232.0 12079.0 10605.0 8912.6 13552.0 8776.8 11079.0 True False 11802.108330669214 12106.10300850936 8657.84837503957 8642.635932670135 10402.039348716888 9941.867673530021 9705.804134005999 11457.849793979474 9240.723729807669 10691.127582185149 1.1039161435446077 1.1323504387583978 0.8098162058664724 0.8083933024119496 0.9729599865640015 0.9299175972884623 0.9078372752916152 1.0717157480256743 0.8643357455770785 1.0 13.384126400188535 -5.242628101076183 24.82957822283774 0.9209196961454941 1.1181333443217771 0.507524664240725 0.0778239233808969 624.8241832035716 824721.0047021947 0.02045360152074945 0.053907295038882155 5.719682199467557e-06 5.242628101076183 0.19721364817628306 AAS(ph)KDTISNNR ddPTM_PC-9_Lapatinib_30min_R1 1 AASKDTISNNR 11 1 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 AAS(0.957)KDT(0.042)IS(0.001)NNR 105.25 0.0090718 0.0 10016.0 15446.0 10776.0 10360.0 10608.0 10013.0 8558.8 9090.9 10878.0 7299.9 True False 9873.170003290554 15410.235735999408 9890.038876562916 11121.908959946884 9984.058296130432 9584.767331443043 9001.932785469973 9513.296401962098 9652.805089581756 8561.677988494666 1.1531816562779276 1.7999083540291931 1.1551519328165956 1.2990337846030535 1.1661333572165626 1.119496358578683 1.0514215551632435 1.111148587315037 1.1274431370291391 1.0 13.063677860311605 -5.899149903248484 1.1392858368944052 1.087454499456117 1.457869930906488 0.3820799557333213 0.16799561222731396 0.49663585583289394 1.293820089513503 0.06009474422538686 0.1362217739863662 1.2613920710658814e-06 5.899149903248484 0.3704154314503709 AAS(ph)LDSVATSR ddPTM_PC-9_AZD4547_30min_R2 3 AASLDSVATSR 11 0 Q9Y2J4;Q9Y2J4-2;Q9Y2J4-4;Q9Y2J4-3 Q9Y2J4 AMOTL2 Angiomotin-like protein 2 1 AAS(1)LDSVATSR;AAS(0.992)LDS(0.007)VATSR;AAS(1)LDSVATSR 163.71 6.8179e-05 42042000.0 113155.2 106783.9 162529.0 208132.0 171106.0 152530.0 133368.0 183287.0 125664.0 156592.0 True False 149136.19982562697 141299.7074020226 160373.75926543787 160150.38300734505 147350.88540454954 142992.2749876034 145237.4936319497 154964.20566625727 132306.34249185925 151109.76174289535 0.9869395471576067 0.9350799430313179 1.0613064134023629 1.059828174964843 0.9751248609289628 0.9462808579560638 0.961139055192629 1.0255075772663849 0.8755644967329838 1.0 17.205237336548855 -6.503525593996542 23.690973055349968 0.9629737873146809 1.0100501081016715 0.1810492007219987 0.049460598435521384 730.3629881597329 894067.8488367975 0.01575707883672374 0.017578389501306496 3.136710270988401e-07 6.503525593996542 0.047076320786990644 AAS(ph)LDSVATSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AASLDSVATSR 11 0 Q9Y2J4;Q9Y2J4-2;Q9Y2J4-4;Q9Y2J4-3 Q9Y2J4 AMOTL2 Angiomotin-like protein 2 1 AAS(0.996)LDS(0.004)VATSR;AAS(0.882)LDS(0.093)VAT(0.025)S(0.001)R;AAS(0.935)LDS(0.065)VATSR 132.86 8.6964e-05 33465200.0 118946.0 132212.0 152195.0 152832.0 178688.0 177519.0 155647.0 157432.0 154786.0 126917.0 True False 139081.20850941335 145337.13360133217 155823.90600275202 144269.31852802902 143675.36912254104 168209.5911356606 140902.98937330444 153299.57681299248 157049.4524236578 149926.047425581 0.9276654116987195 0.9693921509767899 1.0393384517129924 0.9622698724158668 0.9583082565680082 1.1219504150481592 0.9398166082064203 1.0225012894379544 1.0475127912753965 1.0 17.193891526349482 -3.1527969711839345 0.7530465252324849 1.0137409651224423 8.729959991860106e-11 0.21267145072168292 0.05029088999090741 42.78439429783448 2.529762243115671 0.0185916143283196 62.04394542629282 0.0007034010767933191 3.1527969711839345 -1.0137409650351428 AAS(ph)LDSVATSR ddPTM_PC-9_Lapatinib_30min_R1 4 AASLDSVATSR 11 0 Q9Y2J4;Q9Y2J4-2;Q9Y2J4-4;Q9Y2J4-3 Q9Y2J4 AMOTL2 Angiomotin-like protein 2 1 AAS(1)LDSVATSR;AAS(1)LDSVATSR;AAS(0.953)LDS(0.047)VATSR;AAS(0.988)LDS(0.012)VATSR 156.0 0.00021334 45208100.0 168367.0 136591.5 168486.0 138523.0 163745.0 161145.0 125844.3 134208.0 174726.0 116435.0 True False 165966.05570527405 136275.23077390646 154633.73145476796 148710.44351918178 154113.84103505642 154253.20399734244 132359.90209311107 140443.79363039197 155046.51793365137 136560.63461011506 1.2153286793014135 0.9979100577774596 1.132344851034503 1.088970067719404 1.1285378211301986 1.1295583418877646 0.9692390671074632 1.0284354201440515 1.135367585075407 1.0 17.059182142270245 -7.23557316555331 24.95253906985251 1.0356301204635001 1.1102596514448833 0.28109059685634674 0.06402036602735268 1053.6774431006347 1016459.5747867293 0.023632203448248703 0.018298052692537495 5.8133548651974644e-08 7.23557316555331 0.07462953098138314 AAS(ph)LGSSQSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AASLGSSQSSR 11 0 H0Y944;D6RBR1;D6RGF7;E7EN75;P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;F8W7E0;E9PSG1;H0YA91 H0Y944;P20810-6 CAST Calpastatin 1 AAS(0.901)LGS(0.049)S(0.049)QS(0.001)SR 92.781 0.007459899999999999 5737900.0 15953.0 17644.0 17163.0 20405.0 19981.0 14355.0 19807.0 11430.0 16114.0 14618.0 True False 18653.527813887587 19395.579714866282 17572.231011039974 19261.774003902567 16065.866484808657 13602.19852946677 17930.7375697382 11129.974611086065 16349.63676530705 17268.127683975676 1.0802287402123811 1.1232010829329702 1.0176106716738316 1.1154523730894657 0.9303768641760345 0.7877054639854915 1.0383718430792823 0.6445385866247886 0.9468100459136077 1.0 14.075824045075391 -6.396230013381688 4.20425288999249 0.8698060536979191 1.0815577565164176 0.4349102334800439 0.10785566823934863 0.20423390526060572 6.004396656537588 0.032610636758236285 0.037029358311046756 4.015780685783375e-07 6.396230013381688 0.21175170281849853 AAS(ph)LGSSQSSR ddPTM_PC-9_Lapatinib_30min_R1 3 AASLGSSQSSR 11 0 H0Y944;D6RBR1;D6RGF7;E7EN75;P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;F8W7E0;E9PSG1;H0YA91 H0Y944;P20810-6 CAST Calpastatin 1 AAS(0.994)LGS(0.006)SQSSR;AAS(0.99)LGS(0.005)S(0.005)QSSR;AAS(0.906)LGS(0.09)S(0.004)QSSR 80.245 0.016383 13941700.0 41778.0 32289.8 76654.0 39226.0 40488.0 57006.0 38115.0 36940.0 57974.0 32052.7 True False 41182.2380588531 32215.034951979393 70351.80401299697 42110.81089410005 38106.5754424707 54567.98626747646 40088.408201872706 38656.36725610005 51444.357626715646 37592.9664874619 1.095477210413504 0.8569431455409041 1.8714086858897099 1.1201779170086232 1.0136623683363775 1.4515477592244845 1.0663805479475288 1.0282872267872987 1.3684569863320974 1.0 15.198175143504127 AAS(ph)LNYLNQPSAAPLQVSR ddPTM_PC-9_AZD4547_30min_R2 3 AASLNYLNQPSAAPLQVSR 19 0 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 AAS(0.997)LNYLNQPS(0.003)AAPLQVSR;AAS(1)LNYLNQPSAAPLQVSR;AAS(1)LNYLNQPSAAPLQVSR 216.61 8.5152e-28 187265000.0 39351.1 52377.0 73535.0 106014.0 87908.0 70469.0 61781.0 72918.0 68524.0 71302.0 True False 51863.931246272616 69306.8409619403 72559.87785308459 81574.11019997264 75703.49160253356 66062.56229005054 67279.38931434436 61650.19858894598 72146.03874548133 68805.7386826398 0.7537733369231057 1.007282855891015 1.0545614252869286 1.1855713166052295 1.1002496746922377 0.960131575576248 0.9778165397607954 0.8960037312193087 1.0485468236631883 1.0 16.070241276216905 -10.27752735122311 14.911063215659873 0.9999992078854922 1.0039243812520982 0.0 0.11120367085939246 0.0 0.0 0.11333521820792156 0.027487827986687446 5.278039654229838e-11 10.27752735122311 0.003925173366605916 AAS(ph)LNYLNQPSAAPLQVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AASLNYLNQPSAAPLQVSR 19 0 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 AAS(0.999)LNYLNQPS(0.001)AAPLQVSR;AAS(0.975)LNY(0.025)LNQPSAAPLQVSR 212.24 1.8978e-21 109133000.0 48114.0 45708.0 52055.0 56879.0 67377.0 57087.0 67830.0 43092.0 48534.0 53804.0 True False 56258.749905183235 50245.588166351576 53296.18861968684 53692.25403420607 54174.96051984142 54093.25722408002 61404.65135332664 41960.8806597481 49243.71793269286 63558.239287770324 0.8851527439339932 0.790544054231214 0.8385409856679578 0.8447725210118803 0.8523672324300147 0.8510817453448317 0.9661163059490531 0.6601957689507941 0.7747810273619109 1.0 15.955791538754664 -10.775962137964534 5.548668241891954 1.0000122457390355 0.8292434049479583 0.31805166668591944 0.07499344086681883 1.1574390807774063e-05 1.5580998798687607e-06 0.07397857406780467 0.01794115334199571 1.675088904847094e-11 10.775962137964534 -0.17076884079107713 AAS(ph)LNYLNQPSAAPLQVSR ddPTM_PC-9_Lapatinib_30min_R1 2 AASLNYLNQPSAAPLQVSR 19 0 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 AAS(0.991)LNY(0.003)LNQPS(0.006)AAPLQVSR;AAS(0.945)LNY(0.055)LNQPSAAPLQVSR 191.66 1.3663e-11 34951000.0 25341.9 26418.0 26891.0 23197.3 22018.3 24242.3 23026.7 22447.0 27709.0 19131.6 True False 24980.519858864714 26356.83074411709 24680.125782261828 24903.30682592429 20723.226883643358 23205.51334056144 24218.909855491576 23489.96956680233 24588.120631294427 22438.471568745415 1.1132897257431795 1.174626830680819 1.0999022685947477 1.1098486253676987 0.9235578644540466 1.0341842254926328 1.0793475741559035 1.0468613913757632 1.0958019380225195 1.0 14.453686787435096 -6.024540297999548 24.52789651510228 1.0333208404691112 1.1289862155250918 0.4896818719934486 0.04747625779651088 529.9470089634513 529678.6931105632 0.014499216589396088 0.018824598707840517 9.450606965936322e-07 6.024540297999548 0.0956653750559806 AAS(ph)LPGK ddPTM_PC-9_Lapatinib_30min_R1 2 AASLPGK 7 0 Q92545 Q92545 TMEM131 Transmembrane protein 131 1 AAS(1)LPGK;AAS(1)LPGK 76.679 0.030904 12442000.0 175292.0 263820.0 106552.0 66350.0 90459.0 108532.0 111195.0 97075.0 133677.0 38078.0 True False 172792.303935384 263209.1409990523 97791.70586261436 71229.60033711138 85138.37946923678 103890.33936044903 116952.13301868651 101585.45888971043 118620.88857878483 44659.73156425432 3.869085144114191 5.8936570324064625 2.1897065306341186 1.5949401808344859 1.9063791135140096 2.326264303917199 2.618737930621488 2.2746544892137126 2.656103931303722 1.0 15.446686959145058 -5.276024455926761 24.618865376440066 2.1221903704600416 4.881370954246277 0.7487268276722099 0.6507225074211822 254.91252359351736 430279.4731928105 0.16176180880733126 0.3391953441465855 5.2963361840175865e-06 5.276024455926761 2.7591805837862355 AAS(ph)LTEDR ddPTM_PC-9_AZD4547_30min_R2 2 AASLTEDR 8 0 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 AAS(0.95)LT(0.05)EDR;AAS(0.777)LT(0.223)EDR 112.11 0.0037351999999999997 40045000.0 51806.0 92030.0 76167.0 81921.0 66042.0 99523.0 81805.0 108905.0 75247.0 79381.0 True False 68279.23036825912 121776.89775526206 75156.97581336627 63035.37911683318 56873.20826789969 93299.81107710778 89085.48652271605 92076.23463793784 79224.40280020477 76601.89535169589 0.8913517094423629 1.5897373974385094 0.9811372873778686 0.8228958151417025 0.7424517109763731 1.2179830622825734 1.1629671317361703 1.202009874758267 1.0342355425602512 1.0 16.225092468575184 AAS(ph)LTEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AASLTEDR 8 0 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 AAS(0.959)LT(0.041)EDR 114.89 0.0036576 16995000.0 21020.0 52323.0 52025.0 26152.0 40139.0 27392.0 29192.0 14718.0 27900.0 21757.0 True False 24578.27083607581 57517.281649339646 53265.47330591124 24686.788225927976 32274.05109022243 25955.515299139915 26426.72242822224 14331.668095010038 28307.984718385684 25701.371871682775 0.9563019032130198 2.237907063346722 2.072475880736857 0.9605241443600664 1.2557326220310168 1.0098883214766115 1.0282222505538174 0.5576226890363143 1.1014192106054392 1.0 14.649557748293525 -5.772192539276281 24.99879595747012 0.9829870974962028 1.8037961510552223 0.495867283359791 0.3538082812315877 156.7468023167269 364402.87407412136 0.09897016581579213 0.14846934450971558 1.6896916609299961e-06 5.772192539276281 0.8208090535590195 AAS(ph)LTEDRDR ddPTM_PC-9_AZD4547_30min_R2 2 AASLTEDRDR 10 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 AAS(0.949)LT(0.051)EDRDR;AAS(0.966)LT(0.034)EDRDR 107.11 0.010709 274264500.0 34124.0 34366.0 55749.0 63961.0 56221.0 50648.0 39074.0 59623.0 43571.0 48866.0 True False 44974.72217670683 45474.13743624185 55009.73183425053 49215.77963759921 48415.68459509996 47480.972553413354 42551.51030363198 50409.63535023894 45874.074108040535 47155.21621365282 0.953759218766668 0.9643500992595545 1.1665672697800842 1.0436974652944078 1.0267302004456127 1.00690817190371 0.902371226776648 1.0690150400719374 0.9728313809482363 1.0 15.525129747254303 -6.825153067426243 3.887005373251128 0.9876140928035448 1.0359665689700055 0.08982979058930884 0.06591057694810058 0.5790812169433998 17.48314263446552 0.02499465965196546 0.0224279428201325 1.49570839960096e-07 6.825153067426243 0.048352476166460656 AAS(ph)LTEDRDR ddPTM_PC-9_Lapatinib_30min_R1 2 AASLTEDRDR 10 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 AAS(0.986)LT(0.014)EDRDR;AAS(0.981)LT(0.019)EDRDR 117.25 0.004693800000000001 14458700.0 55293.0 56578.0 67039.0 45989.0 51135.0 50383.0 54090.0 54935.0 50497.0 39189.0 True False 54504.51168050568 56446.99711714194 61527.31219802358 49371.18447480666 48127.339835278064 48228.23653850938 56890.51553559736 57487.480650077334 44809.49610301616 45962.76643393985 1.1858405380982124 1.22810269043032 1.3386337892966893 1.074156068168037 1.0470940626354435 1.049289246064542 1.237752205741651 1.250740221059179 0.9749085962312292 1.0 15.488178013921935 -1.5228789615930587 0.04587685255138906 0.6749459279816842 1.9739518963375138 0.2717371257539013 0.10067393123848938 912.4889654021728 3.1840672246280253 22.63039962972365 86.88534414662612 0.029999985057650308 1.5228789615930587 1.2990059683558295 AAS(ph)PAGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AASPAGPR 8 0 Q6NV74 Q6NV74 KIAA1211L Uncharacterized protein KIAA1211-like 1 AAS(1)PAGPR;AAS(1)PAGPR;AAS(1)PAGPR 95.35799999999999 0.006451100000000001 12072400.0 37484.1 63343.0 94007.0 54528.0 132419.0 112069.0 53976.0 62268.0 85627.0 84878.0 True False 43829.417785278274 69631.27442069679 96248.48340353272 51472.972942161185 106472.44752774497 106191.90435380077 48863.00252760079 60633.530978399554 86879.13288463104 100265.7095061216 0.4371326747815246 0.6944674781007314 0.9599341976197395 0.5133656680404637 1.061902898330804 1.05910490113589 0.4873351295102292 0.6047284887032854 0.8664889852430231 1.0 16.61346876848357 -4.832724078936307 3.5092632563671717 0.8009777738279453 0.4128747500576727 0.237060495695407 0.20607663518524952 0.41133986078725515 8.443885104681291 0.05341510794947909 0.3900398656712401 1.4698598296404968e-05 4.832724078936307 -0.3881030237702726 AAS(ph)PAGPR ddPTM_PC-9_Lapatinib_30min_R1 2 AASPAGPR 8 0 Q6NV74 Q6NV74 KIAA1211L Uncharacterized protein KIAA1211-like 1 AAS(1)PAGPR;AAS(1)PAGPR 97.635 0.0057526 10268100.0 77159.0 126379.0 93169.0 98824.0 125421.0 79041.0 124622.0 115551.0 126460.0 74462.0 True False 76058.69851077233 126086.37719020258 85509.00446274062 106091.84662719983 118043.9833671735 75660.60068357032 131074.31737987083 120919.92129966497 112216.74311716392 87332.65748562165 0.870907867693074 1.4437483161549425 0.9791183152398486 1.2148015379546497 1.351659124613357 0.8663494603496635 1.500862577111555 1.3845899664689936 1.284934483250314 1.0 16.4142336208305 -7.283525016673435 24.998416548321387 1.3246458826257295 1.1440490942030108 0.12135056436163894 0.2141192354829645 1609.6812005744555 1821967.1211652237 0.08447366347224884 0.05700170839253659 5.2056502182087296e-08 7.283525016673435 -0.18059678842271865 AAS(ph)PAKPSSLDLVPNLPK ddPTM_PC-9_AZD4547_30min_R2 1 AASPAKPSSLDLVPNLPK 18 1 Q8N3V7-2;Q8N3V7-3;Q8N3V7 Q8N3V7-2 SYNPO Synaptopodin 1 AAS(0.932)PAKPS(0.034)S(0.034)LDLVPNLPK 49.577 0.03533 6578200.0 39674.0 43281.0 60533.0 74951.0 73813.0 65914.0 62207.0 67393.0 56888.0 64965.0 True False 52289.50672953539 57270.73684391502 59730.292868440396 57672.20493140663 63565.33905512384 61792.38716011865 67743.30248907296 56978.9603870764 59894.98354084618 62690.59512380707 0.8340885363469486 0.9135459111659664 0.952779164888762 0.9199498715478827 1.0139533518479007 0.985672365018795 1.08059753389304 0.9088916810336412 0.9554062044324214 1.0 15.935961404937853 -4.084086526972505 0.6943191743193926 0.9874630046046625 0.5357697371924464 0.5249747630828692 0.04460887031925418 6.0228145009618865 1.0911113441252631 0.019009066034689825 2.6726699318618605 8.239739336206664e-05 4.084086526972505 -0.45169326741221616 AAS(ph)PAKPSSLDLVPNLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AASPAKPSSLDLVPNLPK 18 1 Q8N3V7-2;Q8N3V7-3;Q8N3V7 Q8N3V7-2 SYNPO Synaptopodin 1 AAS(0.997)PAKPS(0.002)S(0.001)LDLVPNLPK;AAS(0.99)PAKPS(0.008)S(0.001)LDLVPNLPK 64.565 0.0074611 13272400.0 112579.0 107500.0 111040.0 147293.0 161328.0 141790.0 144457.0 134477.0 126014.0 115421.0 True False 131636.4011633955 118171.88955725041 113687.61472154497 139040.6507403489 129716.9365027378 134354.28279297065 130772.98718188876 130947.12124015903 127856.71635493367 136345.9136278667 0.9654590860909478 0.8667064997619273 0.8338175431633121 1.0197639741506082 0.9513811822536786 0.9853928087618975 0.9591265605422666 0.960403709623137 0.9377377946499894 1.0 17.056911936867067 -5.76293374774301 24.999889015124225 0.97073842942976 0.8864655918817201 0.5073239984390667 0.03818653000764949 31.69235063180125 530209.4718855771 0.010515198359236621 0.016590922506675564 1.7261011911620063e-06 5.76293374774301 -0.08427283754803983 AAS(ph)PAKPSSLDLVPNLPK ddPTM_PC-9_Lapatinib_30min_R1 1 AASPAKPSSLDLVPNLPK 18 1 Q8N3V7-2;Q8N3V7-3;Q8N3V7 Q8N3V7-2 SYNPO Synaptopodin 1 AAS(0.996)PAKPS(0.002)S(0.003)LDLVPNLPK 83.08200000000001 0.0011234 10432000.0 57808.0 55567.0 61120.0 53313.0 54128.0 52228.0 48998.0 47372.0 53911.0 49145.0 True False 56983.647319311116 55438.33802552628 56094.949530022815 57233.815866954435 50944.297459742476 49994.33018941447 51534.876690944744 49573.07605998837 47838.97547200241 57639.647768403775 0.9886189372334739 0.961809104876519 0.9732007689466188 0.9929591536874067 0.8838412348464857 0.86736009196815 0.8940872938365617 0.8600516828134186 0.829966478355654 1.0 15.814773898887061 -6.268328946351163 23.818543627207518 0.8813709613380857 0.977483842315493 0.5116631132610474 0.042616207779680726 207.42207695217436 717096.5360643575 0.0123866469466649 0.014370540755642838 5.391021373403275e-07 6.268328946351163 0.09611288097740733 AAS(ph)PESASSTPESLQAR ddPTM_PC-9_AZD4547_30min_R2 2 AASPESASSTPESLQAR 17 0 Q96BT3 Q96BT3 CENPT Centromere protein T 1 AAS(1)PESASSTPESLQAR;AAS(1)PESASSTPESLQAR 241.39 4.7042e-38 20510200.0 20542.6 18034.8 30610.0 31049.0 26545.2 23850.0 17887.1 27726.0 16992.3 24607.1 True False 27074.719487375954 23864.196410264045 30204.091399781297 23891.13275226808 22859.857183505224 22358.655729720987 19479.01724809581 23441.583780097037 17890.478287531998 23745.612918818322 1.140198805562072 1.0049939115848951 1.271986177111674 1.0061282828936555 0.9626981312993972 0.9415910133025804 0.8203206762735845 0.9871964080371097 0.753422467918436 1.0 14.535373374891938 -6.213823639381468 2.0561156552126705 0.8984617472357728 1.1252242284041727 0.5313669708526847 0.09448631526258597 0.249483399978904 2.071304525768771 0.030304414785662544 0.040689416367448356 6.111901698807206e-07 6.213823639381468 0.22676248116839992 AAS(ph)PESASSTPESLQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AASPESASSTPESLQAR 17 0 Q96BT3 Q96BT3 CENPT Centromere protein T 1 AAS(1)PESASSTPESLQAR;AAS(1)PESASSTPESLQAR 217.32 1.9258000000000002e-22 18648400.0 16643.199999999997 17210.5 19070.5 21677.6 20865.4 23733.1 19306.9 21737.0 20344.9 10341.3 True False 19460.565041816208 18919.04469976796 19525.213045273995 20463.07435172745 16776.974653527173 22488.494456265256 17478.01066214867 21166.42678225526 20642.40567373065 12216.095828314246 1.5930265540902897 1.5486981246428781 1.598318588825966 1.6750911780094673 1.3733499547901225 1.8408904753466184 1.4307362112892446 1.7326670549846293 1.6897710990352626 1.0 13.576495663962167 -11.08636735132449 6.5072008199953295 0.9991231637899364 1.6072764503215293 0.6609524985357353 0.13088365259178195 0.0015477584273919437 0.00010382533267162946 0.11780769101896886 0.028536311005099377 8.196579370606157e-12 11.08636735132449 0.608153286531593 AAS(ph)PESASSTPESLQAR ddPTM_PC-9_Lapatinib_30min_R1 1 AASPESASSTPESLQAR 17 0 Q96BT3 Q96BT3 CENPT Centromere protein T 1 AAS(0.99)PES(0.01)ASSTPESLQAR 209.33 1.4207e-17 9244900.0 13902.0 14652.0 16281.0 9630.7 11102.0 12738.0 12275.0 9443.8 16257.0 13565.0 True False 13703.754930685427 14618.074194216199 14942.439026477452 10338.9738050734 10449.002187371803 12193.225433728296 12910.53943796372 9882.59342428689 14425.965466200645 15909.69217577366 0.8613463277154222 0.9188156522899757 0.9392035283517878 0.6498537929487397 0.6567696013178009 0.7664023476390963 0.8114889524778567 0.6211681103004318 0.906740702888498 1.0 13.957618301907221 -5.743653270870281 24.999463803180184 0.7538791362679422 0.9076912682224033 0.21241314657026822 0.11337825183566026 312.89894965466004 439795.18122748856 0.029296929457870144 0.050607650164283674 1.8044577969037656e-06 5.743653270870281 0.15381213195446108 AAS(ph)PFR ddPTM_PC-9_AZD4547_30min_R2 3 AASPFR 6 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 AAS(1)PFR;AAS(1)PFR;AAS(1)PFR 113.41 0.025604000000000002 695214000.0 981478.0 911534.0 1559413.0 1840212.0 1468829.0 1442152.0 1503298.0 1459304.0 1486526.0 1487481.0 True False 1293567.5879893845 1206169.539481094 1538734.1647176468 1415979.554391984 1264907.4471840763 1351974.0074603173 1637088.6097258853 1233802.098269881 1565100.7295570238 1435404.7429439821 0.9011866474234348 0.8402992573420568 1.071986261910866 0.9864671002046729 0.8812200554596052 0.9418765084246898 1.1405066186198147 0.8595499661923794 1.0903549937748138 1.0 20.45302616218747 -5.245399094298797 24.892818853507386 0.9901966007502139 0.8707429398483413 0.256140874212597 0.08518055924566645 1085.2734296081283 1684222.2203812033 0.02102024746183885 0.05521670742601539 5.683304243641095e-06 5.245399094298797 -0.1194536609018726 AAS(ph)PFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 AASPFR 6 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 AAS(1)PFR;AAS(1)PFR;AAS(1)PFR;AAS(1)PFR;AAS(1)PFR 110.31 0.028877999999999997 900228000.0 1517790.0 1678970.0 1900400.0 2099510.0 2403660.0 1952430.0 2022830.0 1971230.0 1920210.0 1427440.0 True False 1774721.8692810435 1845647.0456738258 1945712.7433071358 1981881.2614032587 1932680.0778176815 1850041.1337434195 1831212.8983790306 1919487.301190827 1948289.438569586 1686223.5723911733 1.052483133517327 1.094544683097141 1.1538877614834848 1.175337181766961 1.1461588542953511 1.097150558226358 1.0859846394996442 1.138334994610988 1.155415847856276 1.0 20.685364401805963 -9.631666721382835 11.254322811544029 0.999996156827697 1.1232144598881295 0.5014402664154931 0.036523824965488054 0.0 0.0 0.03837746035220251 0.009307901333828526 2.3352494508115804e-10 9.631666721382835 0.12321830306043247 AAS(ph)PFR ddPTM_PC-9_Lapatinib_30min_R1 6 AASPFR 6 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 AAS(1)PFR;AAS(1)PFR;AAS(1)PFR;AAS(1)PFR;AAS(1)PFR;AAS(1)PFR 113.41 0.025604000000000002 1295659000.0 2435079.2 2513037.3 3006411.3 2406210.8 2648129.7 2449199.6 2153471.4 2176457.0 2574235.1 1921567.2 True False 2400354.5240691607 2507218.5165324025 2759235.7679972253 2583171.5691159163 2492371.9174693055 2344453.0424711206 2264967.6120755165 2277583.137766907 2284297.6351406514 2253707.5301926513 1.065069221232967 1.1124861957212702 1.2243096014154775 1.1461875751442787 1.1058985622931528 1.040264990493559 1.0049962480632537 1.0105939245684707 1.0135732363397594 1.0 21.103868874489166 -6.754377176960403 2.2553542988400648 1.0086173042045086 1.1408396506628264 0.7211454988497766 0.037116052272823004 0.1726899769597555 1.8041872165810133 0.015592845752894649 0.014449612626867012 1.7604464661516956e-07 6.754377176960403 0.13222234645831787 AAS(ph)PHQVTPQADEK ddPTM_PC-9_AZD4547_30min_R2 1 AASPHQVTPQADEK 14 0 Q96L73-2;Q96L73-3;Q96L73 Q96L73-2 NSD1 Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific 1 AAS(1)PHQVTPQADEK 103.88 0.0006345 14502000.0 42565.0 44370.0 50281.0 52132.0 52894.0 58218.0 59498.0 57907.0 54488.0 62892.0 True False 56099.784592999815 58711.734797359284 49614.24108697821 40113.77283137104 45550.581116899666 54577.61925672519 64793.20673710129 48958.803720481825 57368.124440543324 60690.17022283495 0.9243636059516606 0.9674010565761888 0.8175004437260686 0.6609599657421631 0.7505429783711671 0.8992826854222616 1.0676062779063116 0.8067007151359225 0.9452622101718592 1.0 15.889175246620837 -6.9904112940545415 23.076118555697704 0.9451640831701396 0.8228994977139913 0.27494299589951265 0.09991790442346393 127.63981521990611 307172.86869126704 0.038750409358658845 0.03411624451400861 1.0223243520794873e-07 6.9904112940545415 -0.12226458545614827 AAS(ph)PHQVTPQADEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AASPHQVTPQADEK 14 0 Q96L73-2;Q96L73-3;Q96L73 Q96L73-2 NSD1 Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific 1 AAS(0.998)PHQVT(0.002)PQADEK;AAS(1)PHQVTPQADEK;AAS(0.972)PHQVT(0.028)PQADEK 124.16 3.8967e-05 18801200.0 89876.0 87370.0 103842.0 108606.0 112281.0 77082.3 103716.0 92324.0 86944.0 73802.8 True False 105090.23166808505 96043.51619178562 106317.9871029779 102521.15792540296 90280.34406590268 73039.96849236611 93891.26964118566 89900.59282536388 88215.39151811197 87182.66341735669 1.2054028581921397 1.1016354906710142 1.2194854221649265 1.175935144750265 1.0355309246944766 0.8377808801586235 1.0769488561242258 1.0311751132790707 1.0118455672294784 1.0 16.4117536580328 -6.327583915131758 4.462677749653051 0.9935471850042117 1.1738764569436477 0.6448567917017426 0.06469506632766044 0.1454788993340641 5.7563288353994935 0.020792459397358628 0.024050175984858854 4.703445161635429e-07 6.327583915131758 0.18032927193943604 AAS(ph)PHQVTPQADEK ddPTM_PC-9_Lapatinib_30min_R1 4 AASPHQVTPQADEK 14 0 Q96L73-2;Q96L73-3;Q96L73 Q96L73-2 NSD1 Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific 1 AAS(1)PHQVTPQADEK;AAS(1)PHQVTPQADEK;AAS(1)PHQVTPQADEK;AAS(1)PHQVTPQADEK 164.41 5.4341999999999996e-05 35357300.0 150551.0 198758.0 220203.0 194115.0 224136.0 222516.0 210876.0 202650.0 213919.0 182495.0 True False 148404.1151323282 198297.78806265505 202098.7593481611 208390.86464865698 210952.76114833067 212999.50939013084 221794.12745580773 212065.85881019736 189825.18955306467 214039.01759069733 0.6933507582067048 0.9264562615487989 0.9442145718246131 0.9736115732280121 0.9855808698941589 0.9951433705299736 1.0362322250980442 0.990781312665744 0.8868718969550856 1.0 17.707514286734465 -4.241597610938582 1.3529178722485549 0.9824072266629956 6.2077837020573344e-21 0.8379535050320809 0.03720990744286627 1.8331193134491186 1.0857225355936801 0.010965265044543485 3.5387707250430664 5.733269925268173e-05 4.241597610938582 -0.9824072266629956 AAS(ph)PPASASDLIEQQQK ddPTM_PC-9_AZD4547_30min_R2 4 AASPPASASDLIEQQQK 17 0 Q5VSL9-3;Q5VSL9-2;Q5VSL9 Q5VSL9-3 STRIP1 Striatin-interacting protein 1 1 AAS(0.997)PPAS(0.003)ASDLIEQQQK;AAS(0.999)PPAS(0.001)ASDLIEQQQK;AAS(1)PPASASDLIEQQQK;AAS(0.778)PPAS(0.111)AS(0.111)DLIEQQQK 171.87 1.0385e-05 286746500.0 247988.0 277257.0 339774.0 419123.0 348150.0 365159.0 309374.0 407632.0 322697.0 327562.0 True False 326843.0255291629 366874.9031938576 335268.3747556126 322500.6677358002 299815.3820064395 342325.55000457726 336907.6866631481 344641.8408514939 339754.10462101747 316094.1540821129 1.0340052838948035 1.1606507063036453 1.060659839563242 1.0202677384916872 0.9485002431539921 1.0829860204110264 1.065845990228685 1.0903138713598768 1.0748509589100417 1.0 18.269994828392498 -9.55270992752979 0.005221346498916758 8.476482423073832e-07 2.0790108640556966 0.05887327950128851 0.052901342868025274 47567.89242565223 73.78180994049578 14972.985795682025 14404.117963556395 2.800851430038431e-10 9.55270992752979 2.0790100164074543 AAS(ph)PPASASDLIEQQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AASPPASASDLIEQQQK 17 0 Q5VSL9-3;Q5VSL9-2;Q5VSL9 Q5VSL9-3 STRIP1 Striatin-interacting protein 1 1 AAS(0.537)PPAS(0.355)AS(0.109)DLIEQQQK;AAS(0.998)PPAS(0.002)ASDLIEQQQK;AAS(0.973)PPAS(0.015)AS(0.012)DLIEQQQK 133.87 2.4938e-05 133014400.0 114359.0 128508.0 131244.0 130189.0 146217.0 112009.0 121838.0 113927.0 108570.0 103658.0 True False 133717.72000679342 141265.42496021488 134373.35470564148 122894.93240843267 117566.82847751697 106135.0508594248 110296.62260926765 110936.53696563466 110157.63085573942 122450.3748437234 1.0920156036880238 1.1536544917931373 1.0973698927188644 1.0036305120770486 0.960118159111893 0.8667597056756997 0.9007454877131499 0.9059713954099102 0.899610401326476 1.0 16.90183766470745 -5.9895131672324835 1.6450528383637038 0.9094427549276759 1.1266683000113051 0.8459246367595397 0.036872666184150145 0.12351542289740021 0.6750959994756874 0.011921899970942406 0.020307381017905364 1.0244407201560919e-06 5.9895131672324835 0.21722554508362923 AAS(ph)PPASASDLIEQQQK ddPTM_PC-9_Lapatinib_30min_R1 4 AASPPASASDLIEQQQK 17 0 Q5VSL9-3;Q5VSL9-2;Q5VSL9 Q5VSL9-3 STRIP1 Striatin-interacting protein 1 1 AAS(0.996)PPAS(0.003)AS(0.001)DLIEQQQK;AAS(0.98)PPAS(0.019)AS(0.001)DLIEQQQK;AAS(1)PPASASDLIEQQQK;AAS(1)PPASASDLIEQQQK 140.8 4.2006000000000004e-05 240543000.0 336705.0 432321.0 423846.0 392899.0 448528.0 451172.0 412761.0 412835.0 436095.0 326906.0 True False 331903.5249558652 431319.98728622345 388999.0179728737 421794.10313264217 422146.46487997606 431876.4252933004 434131.7449249163 432016.8212282648 386977.38881606475 383411.26652513596 0.8656592905156741 1.1249538679321691 1.0145737799996846 1.100108786461521 1.101027804179825 1.1264051502904575 1.1322873969235725 1.1267713261105807 1.0093010367776842 1.0 18.54853320560335 -4.755560270448417 24.99847596082301 1.0877331824009702 0.8656589310063421 0.616592674357856 0.05091255395990367 122.9983251838421 522947.2491707621 0.01231991426123786 0.10838494018796577 1.7556572309806086e-05 4.755560270448417 -0.2220742513946281 AAS(ph)PPASASDLIEQQQKR ddPTM_PC-9_AZD4547_30min_R2 3 AASPPASASDLIEQQQKR 18 1 Q5VSL9-3;Q5VSL9-2;Q5VSL9 Q5VSL9-3 STRIP1 Striatin-interacting protein 1 1 AAS(0.992)PPAS(0.005)AS(0.003)DLIEQQQKR;AAS(0.757)PPAS(0.086)AS(0.157)DLIEQQQKR;AAS(0.925)PPAS(0.044)AS(0.032)DLIEQQQKR 88.637 0.00069736 54318000.0 105451.0 63984.0 153917.0 339668.0 259180.0 129985.0 90197.0 154985.0 93707.0 153107.0 True False 138982.22448294162 84665.57672468407 151875.96001241865 261362.79041828692 223197.3307724519 121857.01740158416 98224.35826525815 131035.62945099689 98660.160713368 147746.77053214388 0.9406785947494165 0.5730451936089133 1.027947747794436 1.7689915622313022 1.5106748524421585 0.8247694143343246 0.6648156024763221 0.886893358000598 0.6677652605063433 1.0 17.172767070571055 -6.960273708827958 24.171136268291598 0.7882070069449155 1.1584726714283609 0.24160337134765142 0.3143728615011463 182.4549848035952 111012.36345551907 0.12654324024178837 0.11160045951916853 1.0957873717782547e-07 6.960273708827958 0.37026566448344533 AAS(ph)PPASASDLIEQQQKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AASPPASASDLIEQQQKR 18 1 Q5VSL9-3;Q5VSL9-2;Q5VSL9 Q5VSL9-3 STRIP1 Striatin-interacting protein 1 1 AAS(0.993)PPAS(0.007)ASDLIEQQQKR;AAS(0.974)PPAS(0.023)AS(0.002)DLIEQQQKR;AAS(0.998)PPAS(0.001)AS(0.001)DLIEQQQKR 101.05 0.00025189 62702000.0 118945.0 28166.1 77917.0 148278.0 154530.0 240926.0 142256.0 184859.0 209068.0 137719.0 True False 139080.03922916477 30962.244264729932 79774.83678186807 139970.46438376213 124250.95580288659 228291.41643401654 128780.48183574856 180006.6471243012 212125.2239822024 162686.36451699617 0.8548967188619843 0.19031861924417917 0.4903596992821967 0.8603699812170745 0.763745358572481 1.4032609131797673 0.7915874340058451 1.1064642550635861 1.3038906156148156 1.0 17.311733811691383 -6.133561879521513 1.5626654884930955 1.0977422618198172 0.48145668536543096 0.528895712237466 0.23466193545990943 0.2887850076613943 1.4087685552486204 0.08099645085926774 0.12294880425815645 7.352552267413752e-07 6.133561879521513 -0.6162855764543862 AAS(ph)PPASASDLIEQQQKR ddPTM_PC-9_Lapatinib_30min_R1 4 AASPPASASDLIEQQQKR 18 1 Q5VSL9-3;Q5VSL9-2;Q5VSL9 Q5VSL9-3 STRIP1 Striatin-interacting protein 1 1 AAS(1)PPASASDLIEQQQKR;AAS(0.766)PPAS(0.076)AS(0.158)DLIEQQQKR;AAS(0.921)PPAS(0.073)AS(0.006)DLIEQQQKR;AAS(0.794)PPAS(0.131)AS(0.076)DLIEQQQKR 127.37 1.9791e-05 81299000.0 869470.0 242557.0 285368.0 233249.0 168874.0 217618.0 129675.0 115213.0 282354.0 138884.0 True False 857071.1983587304 241995.37416915802 261906.14459233586 250402.90955585483 158941.16333905834 208310.98543233532 136388.936995352 120566.21658573509 250552.3192005669 162889.91434870267 5.26165908911939 1.485637555503358 1.6078720750731477 1.5372523864173127 0.9757581614218844 1.2788452020816867 0.8373074388349218 0.7401699305190612 1.5381696294848743 1.0 17.31353775374798 -4.75451389637803 4.285063757223658 1.1939069367811077 5.679099277694949 0.9463455925180859 0.28926999765776423 0.05188821360702831 1.9285799533792898 0.07905094584844496 0.7375515286204977 1.759892350581553e-05 4.75451389637803 4.485192340913841 up AAS(ph)PPSYTLDLGESQLAPPPSK ddPTM_PC-9_AZD4547_30min_R2 1 AASPPSYTLDLGESQLAPPPSK 22 0 Q9ULQ0-2;Q9ULQ0 Q9ULQ0-2 STRIP2 Striatin-interacting protein 2 1 AAS(0.932)PPS(0.066)YT(0.002)LDLGESQLAPPPSK 132.94 9.0823e-06 5529100.0 63894.0 56518.0 84186.0 111680.0 97115.0 77788.0 67412.0 91015.0 70855.0 78490.0 True False 84210.96292223973 74786.33823027171 83069.63863384479 85933.90143879992 83632.25857692196 72923.9040630413 73411.5374056519 76950.72306663521 74600.2506466505 75742.0889904967 1.1118119931020864 0.9873815104261923 1.0967434320997862 1.1345594316732137 1.1041715338405207 0.962792352772195 0.9692304290004833 1.015957231867346 0.984924652078325 1.0 16.20880759130082 -6.7599780190664776 24.999945231403604 0.9864938473593223 1.084593789845971 0.6243520152410166 0.03889895922912228 28.895999418523477 494336.35628228216 0.014089259362071851 0.013370817419381002 1.7378887862362176e-07 6.7599780190664776 0.09809994248664866 AAS(ph)PPSYTLDLGESQLAPPPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AASPPSYTLDLGESQLAPPPSK 22 0 Q9ULQ0-2;Q9ULQ0 Q9ULQ0-2 STRIP2 Striatin-interacting protein 2 1 AAS(0.758)PPS(0.234)YT(0.008)LDLGESQLAPPPSK 164.05 8.1954e-09 4291000.0 117450.0 108950.0 126310.0 131100.0 143360.0 123120.0 129430.0 120820.0 109530.0 92333.0 True False 137331.96525676013 119765.83597453425 129321.70943334221 123754.89203193449 115269.63711837077 116663.37045962705 117169.45340794738 117648.60301937145 111131.66903959784 109072.241992374 1.2590917977679599 1.0980413878620732 1.185651886044334 1.1346139931788242 1.0568191779392422 1.0695972534220375 1.0742371410696732 1.0786300975421144 1.0188813121432658 1.0 16.734924468534167 -1.5228787452917587 0.2043098581805649 1.0011615588944722 2.0682907943197906 0.7513277402358147 0.036738936563235416 26.862637910256296 0.32888947180975314 0.06435206776271667 9.235659152063741 0.029999999999211057 1.5228787452917587 1.0671292354253183 AAS(ph)PQDLAGGYTSSLACHR ddPTM_PC-9_AZD4547_30min_R2 3 AASPQDLAGGYTSSLACHR 19 0 P51948;P51948-2;H0YJ92 P51948 MNAT1 CDK-activating kinase assembly factor MAT1 1 AAS(1)PQDLAGGYTSSLACHR;AAS(1)PQDLAGGYTSSLACHR;AAS(1)PQDLAGGYTSSLACHR 105.65 0.00013393 26441000.0 69556.0 61444.0 90008.0 180079.0 127973.0 139357.0 99511.0 140831.0 77103.0 121006.0 True False 91673.36114532332 81304.57139709136 88814.43510981745 138564.56874281546 110206.15792477406 130642.9847600307 108367.28622164915 119068.80492443375 81178.50717110586 116769.61677135984 0.7850788902118595 0.6962819065878187 0.7605954148476834 1.1866491693137189 0.9437913814563824 1.1188097415429181 0.9280435203777123 1.0196899520324352 0.6952023087483196 1.0 16.83330541102189 -5.625660630599933 9.804329340712854 0.9867939452431741 0.7377257020499648 0.43641222908209865 0.12366684876474056 0.26384184415995393 22.933956483262723 0.032704893668093656 0.056690599020645244 2.3677692133683844e-06 5.625660630599933 -0.2490682431932093 AAS(ph)PQDLAGGYTSSLACHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AASPQDLAGGYTSSLACHR 19 0 P51948;P51948-2;H0YJ92 P51948 MNAT1 CDK-activating kinase assembly factor MAT1 1 AAS(1)PQDLAGGYTSSLACHR 151.23 3.8681e-05 6974500.0 17388.0 15572.0 24960.0 19068.0 28288.0 27485.0 25131.0 23491.0 21219.0 14337.0 True False 20331.44497134568 17117.88524823722 25555.141061327125 17999.681779290095 22745.16946710711 26043.638215422776 22750.40974731615 22874.38614077189 21529.287732595916 16936.184608370455 1.200473745503292 1.010728546249842 1.508907800207662 1.062794377571559 1.3429925330328325 1.5377512006187686 1.3433019462997646 1.3506221542641055 1.2712005820930523 1.0 14.04782127980642 -6.3834619537906505 21.249402249587735 1.338477577678385 1.204592210989544 0.07212218323431252 0.17587223069907548 12.193623581208419 2073.1785467085615 0.05273448003497011 0.05979518931363529 4.135595424932671e-07 6.3834619537906505 -0.1338853666888411 AAS(ph)PSPAR ddPTM_PC-9_AZD4547_30min_R2 2 AASPSPAR 8 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 AAS(0.903)PS(0.097)PAR;AAS(0.907)PS(0.093)PAR 89.88600000000001 0.009889299999999998 5073000.0 35689.0 29683.0 41290.0 39358.0 31049.0 33650.0 32210.0 46469.0 62225.0 81504.0 True False 47037.3596226846 39277.4492672981 40742.467621593285 30284.621175038403 26738.382294752126 31545.86018050781 35076.62760096195 39288.283801389625 65514.08646514476 78650.56976788683 0.5980549125263939 0.49939179567565134 0.5180187218202265 0.38505278810330584 0.3399642542153516 0.4010887686332826 0.44598059117028543 0.49952955099164587 0.832976628885075 1.0 16.26316959653596 -8.357174555456202 2.4423633686158355 0.9970012269658699 0.44960780314901366 0.8781696488957591 0.06939648184291532 0.09529149576492482 1.0907843143430676 0.07326545748059542 0.020400207317390676 4.393649865060867e-09 8.357174555456202 -0.5473934238168563 AAS(ph)PSPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AASPSPAR 8 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 AAS(0.98)PS(0.02)PAR;AAS(0.984)PS(0.016)PAR;AAS(0.704)PS(0.296)PAR 101.46 0.0045792 10210100.0 14178.1 28753.0 38436.8 23540.3 90761.0 91567.0 27649.4 50959.0 79689.0 103346.0 True False 16578.17229976054 31607.407818042957 39353.27908437577 22221.413309682313 72977.03358328994 86765.06532550917 25030.248667679072 49621.38024552361 80854.30086822336 122081.8117135141 0.13579559532311056 0.2589034957329693 0.32235169622748544 0.1820206712022645 0.5977715481036853 0.7107124649257195 0.20502848308326913 0.40646005780098254 0.662296043393932 1.0 16.897488751704756 -12.48483525473169 0.11745333454929736 2.2691103105838226 2.5365589409737446e-12 0.6434864904644777 0.1605042199677693 61.20872339560997 0.7713982356309874 21.700398769720508 2.054880994065734 3.2746489185264084e-13 12.48483525473169 -2.269110310581286 AAS(ph)PSPAR ddPTM_PC-9_Lapatinib_30min_R1 2 AASPSPAR 8 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 AAS(0.916)PS(0.084)PAR;AAS(0.894)PS(0.106)PAR 100.25 0.0049517 8070000.0 30854.0 56096.0 32875.0 48763.0 49683.0 24587.9 75855.0 75785.0 46082.0 40163.0 True False 30414.01630206936 55966.11315852799 30172.14440116982 52349.193688599415 46760.7436205362 23536.332834194363 79782.4007386345 79306.24776674432 40891.75989502722 47105.12103616643 0.6456626293077148 1.1881110148418526 0.640527903070331 1.1113270178927401 0.9926891724709546 0.4996555006434143 1.6937097067934308 1.6836014009146578 0.8680958459618711 1.0 15.523596290594906 -7.264675587337726 24.994860566166363 1.3683185082580136 0.8712079500721361 0.332990940264681 0.31719737992027586 316.2564647509677 2442590.06403087 0.1255078831507839 0.08863187889051118 5.4365628444281155e-08 7.264675587337726 -0.49711055818587746 AAS(ph)PSPQSVR ddPTM_PC-9_AZD4547_30min_R2 3 AASPSPQSVR 10 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 AAS(0.609)PS(0.389)PQS(0.002)VR;AAS(0.891)PS(0.109)PQSVR;AAS(0.524)PS(0.476)PQSVR 132.56 0.00014227 309753000.0 216548.0 215819.0 285662.0 419210.0 341826.0 270524.0 244564.0 329971.0 250110.0 291328.0 True False 285405.7595217887 285578.2711794296 281873.9352317649 322567.61122993653 294369.36024625384 253608.09151476112 266329.72221675486 278981.56392925006 263330.30399031506 281128.69539334223 1.0152139009589973 1.0158275404076476 1.0026508849883857 1.147401942653399 1.0470982331931142 0.9021067421094259 0.947358724245914 0.9923624606833962 0.9366895244253722 1.0 18.10087119456835 -6.7384967894242225 24.513231791269053 0.9547046072871506 1.0472477138018 0.49455130131272307 0.04544006194702044 167.10981461802956 178549.4789519076 0.015702945774237115 0.01569201555088993 1.8260102480321185e-07 6.7384967894242225 0.09254310651464936 AAS(ph)PSPQSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AASPSPQSVR 10 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 AAS(0.891)PS(0.109)PQSVR;AAS(0.544)PS(0.455)PQS(0.001)VR;AAS(0.905)PS(0.095)PQSVR;AAS(0.996)PS(0.004)PQSVR 136.81 0.00011605 542157000.0 359625.0 409550.0 450409.0 445566.0 468237.0 393952.0 407180.0 385731.0 364757.0 281608.0 True False 420502.40958248207 450207.4173783429 461148.4587456449 420602.3815644618 376489.32111742883 373292.46360713977 368608.9626720856 375605.96996577806 370090.88107255177 332661.3011922985 1.264055686896403 1.353350737716545 1.3862401700854077 1.2643562087233227 1.1317496798336488 1.1221397327227853 1.108060845523499 1.1290942728221187 1.112515581902978 1.0 18.34369452032322 -6.186530728514119 2.600846249897002 1.1047436716721208 1.336440532893618 0.8495629759925758 0.04534029785474589 0.10261279175909067 1.361247467813001 0.014149243344945007 0.018827128646051974 6.508325595414319e-07 6.186530728514119 0.23169686122149713 AAS(ph)PSPQSVR ddPTM_PC-9_Lapatinib_30min_R1 4 AASPSPQSVR 10 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 AAS(0.857)PS(0.143)PQS(0.001)VR;AAS(0.553)PS(0.439)PQS(0.008)VR;AAS(0.994)PS(0.006)PQSVR;AAS(0.914)PS(0.086)PQSVR 150.09 0.00015919 524521000.0 366106.0 412782.0 470872.0 400503.0 417155.0 384322.0 359251.0 382332.0 438755.0 370194.0 True False 360885.26130438247 411826.2286402499 432158.7217784841 429957.3266588418 392618.7630582856 367885.443958339 377851.2589513572 400096.540491587 389337.791605023 434181.5396475023 0.8311851802759126 0.9485116040967518 0.9953410781336756 0.9902708599907541 0.9042732755912188 0.8473078893612406 0.8702609955690935 0.9214959733580848 0.896716594448289 1.0 18.727938861778235 -6.490261622735099 23.707221453408042 0.8972601407970139 0.9458952074527626 0.06758227389691274 0.056521376039750444 710.8230775322792 516649.82862740714 0.01783806674999543 0.02020569616916513 3.2339878002826307e-07 6.490261622735099 0.04863506665574868 AAS(ph)PVLLSSNSQK ddPTM_PC-9_AZD4547_30min_R2 2 AASPVLLSSNSQK 13 0 P41970;G3V1Z7 P41970 ELK3 ETS domain-containing protein Elk-3 1 AAS(0.984)PVLLS(0.008)S(0.008)NSQK;AAS(1)PVLLSSNSQK 115.06 0.00029513 77578000.0 60610.0 54873.0 76953.0 117139.0 106049.0 80798.0 70132.0 96483.0 84985.0 79531.0 True False 79882.71923368306 72609.62414999983 75932.55293980306 90134.41332950925 91325.92688898715 75745.68828721144 76373.61213631374 81573.76930877542 89477.13359968386 76746.64389735251 1.0408627032671944 0.9460951054369767 0.9893924878508267 1.1744411058555562 1.1899663913790708 0.9869576627809311 0.9951394387807017 1.0628968925061937 1.1658768260845151 1.0 16.22781604288555 -5.5873726654590214 24.725265391148447 1.081716857513443 0.9870450292842576 0.23414731107664333 0.07448400950908778 78.4923333297639 30090.940402158198 0.02156123428021278 0.03734516018693557 2.5859929379701475e-06 5.5873726654590214 -0.0946718282291854 AAS(ph)PVLLSSNSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AASPVLLSSNSQK 13 0 P41970;G3V1Z7 P41970 ELK3 ETS domain-containing protein Elk-3 1 AAS(1)PVLLSSNSQK;AAS(1)PVLLSSNSQK;AAS(0.996)PVLLS(0.003)S(0.001)NSQK 138.55 5.4000000000000005e-05 66494000.0 104311.0 90580.0 120001.0 133077.0 138907.0 102494.0 129786.0 112052.0 86832.0 83215.0 True False 121968.79206383953 99572.18377763456 122862.27894632649 125621.12713145542 111689.17050224285 97119.0342096249 117491.73051073075 109110.75372890782 88101.75372999535 98301.22077042263 1.240765792204059 1.0129292698223982 1.2498550677540916 1.2779203162169979 1.1361931177140423 0.9879738364230626 1.1952214793458826 1.1099633643790678 0.8962427225166654 1.0 16.584921712580197 -8.13982009272567 4.793508615675355 0.9507115607979482 1.1525073577232323 0.43560984508600753 0.09350246261241024 0.21685194717188877 7.322209486473741 0.06926267645230337 0.02464666084897949 7.247361211480692e-09 8.13982009272567 0.20179579692528415 AAS(ph)PVLLSSNSQK ddPTM_PC-9_Lapatinib_30min_R1 4 AASPVLLSSNSQK 13 0 P41970;G3V1Z7 P41970 ELK3 ETS domain-containing protein Elk-3 1 AAS(1)PVLLSSNSQK;AAS(1)PVLLSSNSQK;AAS(1)PVLLSSNSQK;AAS(0.894)PVLLS(0.053)S(0.053)NSQK 188.63 2.7374000000000003e-05 81367800.0 152192.0 156475.0 178236.0 166823.0 161064.0 155191.0 146382.0 137066.0 161664.0 108346.0 True False 150021.71417140507 156112.6917512953 163582.1240908566 179091.71992521433 151590.53218400743 148553.84269789033 153960.94370737317 143434.58674403414 143455.69792260925 127073.46173802954 1.180590440517666 1.2285231677494715 1.2873035947355564 1.409355796841546 1.1929361969891201 1.1690390791756664 1.211590064531129 1.1287532800494107 1.1289194137038054 1.0 16.955303241077203 -8.13547297073541 0.5973602308101152 1.004838454358461 1.2672695108416745 0.6122053770372815 0.06335866445630897 0.5425615930041222 0.4489576754603534 0.06850356307239688 0.033781961378330616 7.320268810721167e-09 8.13547297073541 0.2624310564832135 AAS(ph)QILENGEEAPGPDPSLDR ddPTM_PC-9_AZD4547_30min_R2 1 AASQILENGEEAPGPDPSLDR 21 0 A0A087X1N4;Q8IYJ3-2;Q8IYJ3 A0A087X1N4 SYTL1 Synaptotagmin-like protein 1 1 AAS(1)QILENGEEAPGPDPSLDR 162.83 1.2371e-23 0.0 0.0 630.04 1023.7 2541.6 956.59 781.99 1268.3 2738.3 482.31 2124.6 True False 0.0 833.6881088962866 1010.1250691263023 1955.6733873285636 823.7839904453263 733.0920416806928 1381.1762429773362 2315.158654874116 507.80392194461973 2050.218400677911 0.0 0.4066338047793469 0.4926914463319133 0.9538853942008881 0.40180304214074924 0.35756777982203924 0.6736727377535222 1.1292253811148127 0.24768284285065081 1.0 11.001561886486476 -4.983873769433997 1.921298124002124 0.6584947281540485 3.2910178607195488e-31 0.3472839642870149 0.27875586505590283 0.6296880924258305 3.3817157415895487 0.0759063551548686 0.6460702723304099 1.0378300241501552e-05 4.983873769433997 -0.6584947281540485 AAS(ph)SDQLR ddPTM_PC-9_AZD4547_30min_R2 2 AASSDQLR 8 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 AAS(0.999)S(0.001)DQLR;AAS(0.998)S(0.002)DQLR 97.59700000000001 0.0057644 35729000.0 80847.0 111540.0 140944.0 140302.0 136945.0 152361.0 123430.0 145848.0 152170.0 124064.0 True False 106554.66427793389 147593.1237164179 139074.99046882632 107957.54154429179 117932.55059276728 142833.84258431982 134415.03088440644 123310.54285362441 160213.3955387879 119720.55712214255 0.8900281358465746 1.2328135389968067 1.161663408623615 0.9017460671699867 0.9850651669825501 1.193060289876503 1.1227397709757745 1.0299863767574957 1.3382279483993158 1.0 16.869311372012945 -6.763194044479738 24.999672570795397 1.1377980777499452 1.0450095560999904 0.13061838391846747 0.1307975340242384 115.9558342990058 1652072.5644783115 0.04524378367726943 0.04198323238817295 1.7250669530857855e-07 6.763194044479738 -0.09278852164995488 AAS(ph)SDQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AASSDQLR 8 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 AAS(0.941)S(0.059)DQLR 68.626 0.043082999999999996 18677000.0 27026.0 31265.0 32724.0 28939.0 34959.0 29805.0 35086.0 17855.0 27811.0 22337.0 True False 31600.968012168636 34368.78257681331 33504.264266461105 27317.641651503865 28109.034905281314 28241.973331296213 31762.400079357514 17386.325168936277 28217.683261757156 26386.52128040528 1.1976178169282066 1.3025128326535294 1.269749199237623 1.035287727442497 1.065280057441872 1.0703181761314176 1.2037357915362787 0.65890933420797 1.069397627746849 1.0 14.687513542175713 -6.217991789560201 0.5911577859399016 0.9407316858960452 1.3002313077000776 0.38303284286919603 0.13610915371275684 1.0485263654700496 0.7467936726615504 0.09776330608821145 0.20670839773179273 6.053523189743634e-07 6.217991789560201 0.3594996218040324 AAS(ph)SDQLR ddPTM_PC-9_Lapatinib_30min_R1 2 AASSDQLR 8 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 AAS(0.999)S(0.001)DQLR;AAS(0.998)S(0.002)DQLR 105.17 0.0038465000000000005 34636000.0 64700.0 112942.0 100022.0 71389.0 129765.0 101599.0 111719.0 102006.0 104954.0 91509.0 True False 63777.36613547317 112680.48973813602 91798.57725608558 76639.18520672277 122132.47782780594 97253.8476088366 117503.26317473466 106745.57115121112 93132.97530538375 107326.20872192194 0.5942385079558513 1.0498879172196123 0.8553230226731678 0.7140770751093234 1.1379557638549076 0.9061518967917479 1.0948235717445407 0.9945899740834484 0.8677561279247987 1.0 16.711642895135924 -6.255965380431861 24.976885268402526 0.9999698720194602 0.8246993267447559 0.34727837495284475 0.1308991104621217 576.7526891133355 2631618.054827889 0.03794464285052533 0.04756695278643233 5.546699264323552e-07 6.255965380431861 -0.17527054527470431 AAS(ph)SLNLSNGETESVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AASSLNLSNGETESVK 16 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6;E7EN19 C9J840;O95819-6;E7EN19 MAP4K4 1 AAS(0.494)S(0.494)LNLS(0.011)NGETESVK 193.54 1.0414e-11 11722000.0 13025.0 14166.0 14936.0 19763.0 15988.0 13056.0 16418.0 16984.0 16749.0 13734.0 True False 15229.87524452366 15572.30686016752 15292.130885095434 18655.74318251049 12855.266170818315 12371.320376225567 14862.768183973436 16538.187996035493 16993.922439005073 16223.865481715819 0.9387328353830117 0.9598394955701155 0.9425701231515731 1.1498950853318761 0.7923676503177439 0.7625383969170576 0.9161052401922137 1.0193740828703193 1.0474644564920181 1.0 13.98582997511564 -7.774440289554087 8.813867915755159 1.0253695795180264 0.922790213800056 0.17450062112678733 0.09873957539209428 0.33744531606569467 172.41519865017364 0.05672353256467041 0.02860265146211846 1.68096902353408e-08 7.774440289554087 -0.10257936571797044 AAS(ph)SPDGFFWTQGSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AASSPDGFFWTQGSPK 16 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 AAS(0.838)S(0.162)PDGFFWTQGSPK 109.79 0.0038058999999999996 0.0 10185.0 13657.0 9143.8 7626.4 10820.0 10097.0 10686.0 5846.7 8348.7 7903.4 True False 11909.119337080498 15012.776704031327 9361.822870054602 7199.117533122399 8699.898672019897 9567.495545247359 9673.74472005969 5693.230320090714 8470.783943311342 9336.22385672002 1.275582025436179 1.608013789560695 1.002741902264496 0.7710952140399487 0.9318434096626648 1.0247714377971855 1.0361517534840095 0.6098001084231549 0.9073030031530626 1.0 13.188623437942567 -5.38516559687813 5.051813453242949 0.8934298267999318 1.436866903793359 0.6922815515301792 0.14279657419594802 0.1141595957549688 4.17056630053606 0.0379466589312504 0.08161835497607686 4.119404158948627e-06 5.38516559687813 0.5434370769934272 AAS(ph)SPDGFFWTQGSPKPGTASPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AASSPDGFFWTQGSPKPGTASPK 23 1 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 AAS(0.461)S(0.461)PDGFFWT(0.079)QGSPKPGTASPK 59.358999999999995 0.0028605 13186000.0 19568.0 14411.0 24507.0 20486.0 19143.0 22234.0 23535.0 19203.0 25720.0 20913.0 True False 22880.47591438304 15841.628841018915 25091.339823315066 19338.235836508116 15392.066569175313 21068.009899279987 21305.594421355505 18698.94159726034 26096.10634254048 24704.361352783075 0.9261715203904851 0.6412482644176621 1.0156643786498207 0.7827863088769774 0.6230505759438026 0.852805283991143 0.8624223924313396 0.7569085203311198 1.0563360035858858 1.0 14.592478139844806 -8.264639890933598 24.789072183531694 1.028168034202082 0.8053716294373208 0.37624173813485284 0.11355328876103449 261.80149968414514 2027684.2589311707 0.09240392914938128 0.027760374920636943 5.437009715682959e-09 8.264639890933598 -0.22279640476476126 AAS(ph)SSSPGSPVASSPSR ddPTM_PC-9_AZD4547_30min_R2 1 AASSSSPGSPVASSPSR 17 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 AAS(0.697)S(0.009)S(0.101)S(0.009)PGS(0.186)PVASSPSR 279.19 5.7778999999999986e-83 6349200.0 11901.0 12190.0 17969.0 25978.0 17321.0 17442.0 16491.0 24700.0 17620.0 17047.0 True False 15685.270443822172 16130.179111557583 17730.719319263982 19989.17345609907 14916.27813222331 16351.348982716716 17958.667052699886 20883.182549534624 18551.357228057062 16450.18971870298 0.9535008843082743 0.9805466920067456 1.0778428469493644 1.2151333083637605 0.9067541704558157 0.9939915139170774 1.0916996922097408 1.2694797389352641 1.1277290745750592 1.0 14.005816602090734 -7.5225899402026055 24.999986116093766 1.1552805972223747 1.0270531797892952 0.1946114429836664 0.09950077299700295 15.57829651676711 1348914.7928064002 0.047107587483329126 0.027577131339444304 3.0019956582814055e-08 7.5225899402026055 -0.12822741743307953 AAS(ph)SSSPGSPVASSPSR ddPTM_PC-9_Lapatinib_30min_R1 1 AASSSSPGSPVASSPSR 17 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 AAS(0.758)S(0.145)S(0.085)S(0.009)PGS(0.003)PVASSPSR 239.19 1.2717999999999998e-37 13545000.0 14544.0 9356.1 9967.0 9647.3 11783.0 14402.0 16190.0 17738.0 15129.0 13496.0 True False 14336.599892957058 9334.436525287067 9147.551733732607 10356.794624449376 11089.94710626931 13786.060032701755 17028.238981721603 18562.172235752638 13425.01270456723 15828.765617710396 0.905730758746987 0.5897134843441618 0.5779068282808894 0.6543021025506516 0.7006198319002876 0.8709497863356375 1.0757780734758715 1.1726860251808835 0.848140216919147 1.0 13.95026113302556 -6.934832364863429 2.5992727687489046 1.0370032824173885 0.6693502473383495 0.6621248202849538 0.11367676138665866 0.1618061056272249 2.217091847004526 0.0454655621899741 0.03793749460621565 1.1618970127641262e-07 6.934832364863429 -0.367653035079039 AAS(ph)TDLGAGETVVGK ddPTM_PC-9_Lapatinib_30min_R1 1 AASTDLGAGETVVGK 15 0 H7C207;Q15032-2;Q15032-4;Q15032;Q15032-3 H7C207 R3HDM1 R3H domain-containing protein 1 1 AAS(0.823)T(0.177)DLGAGETVVGK 71.344 0.02187 2799900.0 11091.0 9173.1 10623.0 11858.0 12613.0 12868.0 16082.0 16877.0 18277.0 20239.0 True False 10932.840306159704 9151.86025054358 9749.617945965841 12730.076877128386 11871.128138112093 12317.665636773101 16914.647270169666 17661.167032517613 16218.451794657634 23737.284183227664 0.4605767122207119 0.385547907667134 0.41073013537305775 0.5362903683026733 0.500104731715687 0.5189163824173508 0.7125771903645679 0.7440264394271638 0.683247993724459 1.0 14.5348672631595 -7.96586104193809 0.325512772171715 1.0353308106881596 0.3553011325829931 0.9151363373147591 0.052272862511512 0.3677083338041316 0.13165092386777857 0.09021158260584954 0.08002965669064227 1.0817800252542511e-08 7.96586104193809 -0.6800296781051665 down AAS(ph)VECISPVSPR ddPTM_PC-9_AZD4547_30min_R2 2 AASVECISPVSPR 13 0 Q5T7I8;Q92529-2;Q92529 Q5T7I8 SHC3 SHC-transforming protein 3 1 AAS(0.933)VECIS(0.059)PVS(0.008)PR;AAS(0.999)VECIS(0.001)PVSPR 115.12 0.00029435 12502500.0 13504.4 5418.1 27627.0 26020.1 33624.0 24025.0 13107.6 37408.0 17741.7 19544.4 True False 17798.51829103034 7169.394868279749 27260.64792883887 20021.56795153758 28955.88799248751 22522.712952056467 14274.15100721417 31627.453150323498 18679.490041601577 18860.15650485237 0.943709999779223 0.38013443135719455 1.4454094228658818 1.0615801595488565 1.5352941522535986 1.1941954429838262 0.756841599036662 1.6769454241902149 0.9904207336135142 1.0 14.203054027345999 -5.265055789948791 24.999671755178838 1.2216756298236737 0.6619222113789127 0.35582855857405016 0.2931839280713452 283.9425736163727 1962864.2899721295 0.07201201406579487 0.15992627069876583 5.431805494371062e-06 5.265055789948791 -0.559753418444761 AAS(ph)VECISPVSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AASVECISPVSPR 13 0 Q5T7I8;Q92529-2;Q92529 Q5T7I8 SHC3 SHC-transforming protein 3 1 AAS(0.997)VECIS(0.003)PVSPR;AAS(1)VECISPVSPR;AAS(0.994)VECIS(0.006)PVSPR;AAS(1)VECISPVSPR 161.21 6.7352e-05 27998100.0 26394.6 27921.9 64669.3 37794.2 58898.0 39956.1 48130.2 53204.9 32414.8 22333.1 True False 30862.684462887086 30693.801702591536 66211.26137168607 35676.71350444962 47357.35970283068 37860.73177730597 43570.95902352774 51808.32775025131 32888.80512722324 26381.914241277664 1.169842498183802 1.1634410385038478 2.509721651209472 1.3523170903432447 1.7950691246177437 1.4351017682435008 1.651546533926479 1.9637819786856474 1.2466421058925574 1.0 14.687261628225498 -8.493710957266472 6.781992223531533 1.0002312465776384 1.6335716585810436 0.23227070423618212 0.3818156844630878 0.23705966073660178 39.14815934292349 0.3633247548444261 0.09403339630690913 3.2084039528597224e-09 8.493710957266472 0.6333404120034052 AAS(ph)VECISPVSPR ddPTM_PC-9_Lapatinib_30min_R1 4 AASVECISPVSPR 13 0 Q5T7I8;Q92529-2;Q92529 Q5T7I8 SHC3 SHC-transforming protein 3 1 AAS(0.998)VECIS(0.002)PVSPR;AAS(1)VECISPVSPR;AAS(1)VECISPVSPR;AAS(0.778)VECIS(0.222)PVSPR 167.22 7.8434e-05 28159400.0 45702.4 49374.2 79164.1 55055.0 66142.1 55457.7 42907.1 46340.1 79095.3 38936.7 True False 45050.67539520628 49259.87707344178 72655.5332802629 59103.928358096084 62251.75171837186 53085.90344921289 45128.61969194733 48493.230218852215 70186.7544035664 45666.85671510848 0.9865070345492305 1.0786789504858691 1.5909904579928194 1.294241220209537 1.3631713718929206 1.1624602012875103 0.9882138368638129 1.0618911330240222 1.5369298316594173 1.0 15.478859870873151 -6.914054557968605 8.656420489807179 1.1411119368691192 1.2721432227127902 0.06729037285109996 0.2087353350482748 0.7910745173087254 71.24769640196375 0.07656046761046875 0.06752117939986237 1.2188364737486277e-07 6.914054557968605 0.13103128584367107 AAS(ph)VIPGSTSR ddPTM_PC-9_AZD4547_30min_R2 2 AASVIPGSTSR 11 0 J3KPJ3;Q8N5S9;Q8N5S9-2 J3KPJ3 CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 1 AAS(0.999)VIPGS(0.001)TSR;AAS(1)VIPGSTSR 121.21 0.00079051 88993000.0 77690.0 55378.0 67432.0 104966.0 83134.0 60680.0 65133.0 117516.0 70380.0 74225.0 True False 102393.80394761327 73277.8555241867 66537.8076207139 80767.71040853394 71592.27909729531 56885.670007524954 70929.71082065986 99356.60244903278 74100.14311638237 71626.40534233174 1.4295538559869312 1.0230564436950593 0.9289563995666491 1.1276247917581816 0.9995235521750209 0.7941997052015272 0.9902732167230495 1.3871504785723525 1.034536673482742 1.0 16.128203920023147 -4.7604884197065624 24.956395435703126 1.0338653493827006 1.4295543294445603 0.40829362760078824 0.1436629776170002 25.373704547401662 665537.7293653497 0.03809632848617431 0.22507317383752798 1.7358475479540546e-05 4.7604884197065624 0.3956889800618597 AAS(ph)VIPGSTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AASVIPGSTSR 11 0 J3KPJ3;Q8N5S9;Q8N5S9-2 J3KPJ3 CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 1 AAS(0.999)VIPGSTSR;AAS(1)VIPGSTSR;AAS(1)VIPGSTSR 122.34 0.001756 14008000.0 308238.0 294933.0 237585.0 210445.0 260346.0 189285.0 112152.0 210212.0 115760.0 93589.0 True False 360416.60542199534 324211.99909570755 243249.92744613 198654.4489218956 209333.07020939837 179358.56138280156 101528.1506498348 204694.15773802466 117452.77100359592 110555.94484988389 3.2600382178577516 2.932560519797756 2.2002428523985924 1.7968680851277101 1.8934582893180187 1.6223330335274135 0.9183418475387525 1.8514984247655284 1.0623831324771973 1.0 16.7544170787393 -1.5228787509370214 0.2946472310727647 1.0723499546806516 20.753200579335754 0.8776602035407229 0.26057465668417756 16.682678390181575 0.2372697603246742 0.26617475075534736 171.99184886477448 0.029999999609250125 1.5228787509370214 19.680850624655104 up AAS(ph)VIPGSTSR ddPTM_PC-9_Lapatinib_30min_R1 2 AASVIPGSTSR 11 0 J3KPJ3;Q8N5S9;Q8N5S9-2 J3KPJ3 CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 1 AAS(1)VIPGSTSR;AAS(0.999)VIPGS(0.001)TSR 116.03 0.0013015000000000001 75409000.0 173838.0 175373.0 165860.0 178381.0 113605.0 94848.0 81371.0 75138.0 122898.0 131900.0 True False 171359.03824201555 174966.93459338511 152223.6310381152 191499.73380157203 106922.97725602365 90791.572141487 85583.99222863912 78629.18578475485 109055.93306668682 154698.73925429792 1.107695118059954 1.131017197921502 0.9840004629118919 1.2378881348656607 0.6911690280827745 0.5868927735231338 0.5532300563093399 0.5082729579036975 0.7049568315318832 1.0 17.239101913764266 -6.33554131564483 5.8550665772427966 0.635041800416294 1.1061361961719507 0.6986514075265258 0.1406676798620345 0.11441422102188119 6.9738092960236955 0.041827286421121594 0.047679216834142106 4.618050570029214e-07 6.33554131564483 0.4710943957556567 AAS(ph)VPCSVAPEK ddPTM_PC-9_AZD4547_30min_R2 1 AASVPCSVAPEK 12 0 Q9C073;D6RFX7 Q9C073 FAM117A Protein FAM117A 1 AAS(0.925)VPCS(0.075)VAPEK 89.23100000000001 0.0076042 4543400.0 18469.0 24704.0 26268.0 40374.0 38170.0 36705.0 19914.0 29065.0 25914.0 26796.0 True False 24341.757820935363 32689.084886949822 25919.669156793698 31066.398072081927 32870.75436215944 34409.830547564314 21686.307421470232 24573.672097256003 27283.761135520454 25857.880196067617 0.9413671049739483 1.2641827032643254 1.002389560174986 1.2014286490818533 1.2712083942270842 1.3307289803592348 0.8386730566091886 0.950335909630871 1.0551429942687134 1.0 14.658316388805394 -7.268162733225853 24.98642529836857 0.9568993201415048 1.1715057043883492 0.4046557771710313 0.12323602691175442 553.2047122061791 2055900.30490629 0.05126813102297724 0.035435588805991035 5.3930850192472984e-08 7.268162733225853 0.21460638424684442 AAS(ph)YTEEDENHTAK ddPTM_PC-9_AZD4547_30min_R2 2 AASYTEEDENHTAK 14 0 Q14126 Q14126 DSG2 Desmoglein-2 1 AAS(0.993)YT(0.007)EEDENHTAK;AAS(0.958)YT(0.042)EEDENHTAK 178.22 1.3380000000000002e-26 0.0 25145.0 37880.0 30930.0 30604.0 31035.0 24347.0 30607.0 39346.0 28213.0 17063.3 True False 33140.586951508965 50123.96921622649 30519.847990697017 23548.720627086615 26726.325953094532 22824.578241153737 33330.963706384435 33265.97978113314 29704.28158201893 16465.919060664313 2.0126776300436835 3.0441039477698157 1.853516216025035 1.4301491790605552 1.623129923973783 1.386170924141108 2.024239496355189 2.0202929249544743 1.8039856428652044 1.0 14.007195419102397 -5.440817910963538 6.794073205026295 1.6614325570485426 2.5214246739944315 0.4824297406088198 0.37174884289554755 0.20471526824851852 14.296858791793774 0.09487397753849937 0.19858054919821722 3.62394909875478e-06 5.440817910963538 0.8599921169458888 AAS(ph)YTEEDENHTAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AASYTEEDENHTAK 14 0 Q14126 Q14126 DSG2 Desmoglein-2 1 AAS(0.834)YT(0.166)EEDENHTAK 178.23 7.6717e-05 6060500.0 20812.0 18042.0 20575.0 15274.0 30992.0 13808.0 14861.0 11850.0 13743.0 14729.0 True False 24335.06054426307 19833.090524575917 21065.58603112201 14418.247298976135 24919.340077933506 13083.884172405233 13453.258495677255 11538.950056112843 13943.965375798365 17399.25110530015 1.398626894743196 1.139881849198347 1.2107179730686812 0.828670568159342 1.4322076235995347 0.7519797313816355 0.7732090544735647 0.6631865927032833 0.8014118131527375 1.0 14.086737590800405 -6.784071164653303 24.969382462975002 0.7753596470491139 1.1783102882063783 0.5714679518868059 0.17379711792893981 168.3810771826311 185771.5185057465 0.05914632923754059 0.05219827497704902 1.6441022941494348e-07 6.784071164653303 0.4029506411572644 AAS(ph)YTEEDENHTAK ddPTM_PC-9_Lapatinib_30min_R1 2 AASYTEEDENHTAK 14 0 Q14126 Q14126 DSG2 Desmoglein-2 1 AAS(1)YTEEDENHTAK;AAS(0.499)YT(0.499)EEDENHT(0.002)AK 207.4 1.5371999999999998e-60 6391500.0 47315.0 74359.0 39886.0 25127.0 38015.0 29987.0 27505.0 21817.5 41225.0 20727.9 True False 46640.27942349167 74186.8263041034 36606.72704441245 26974.92340121479 35779.03244036559 28704.525913111192 28929.0743170014 22831.220698699588 36581.806381504655 24310.68989680937 1.9185090847468267 3.051613369221577 1.5057872565441617 1.1095910282971888 1.4717407277306997 1.1807367884232067 1.1899734001706863 0.9391432656008684 1.5047621658119128 1.0 14.569303214774703 -5.424796683906301 5.409199794374893 1.2133356535645499 2.4727944213755055 0.732735447602302 0.3057114897448627 0.0976096560260141 4.264263949048427 0.07438874516267717 0.15776910791608442 3.7601339474086856e-06 5.424796683906301 1.2594587678109557 AASAPAKES(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 AASAPAKESPR 11 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 AASAPAKES(1)PR;AASAPAKES(1)PR 63.292 0.024274 1575140000.0 365390.0 331780.0 460330.0 593080.0 469680.0 456860.0 392080.0 510220.0 393260.0 476670.0 True False 481576.41941586265 439021.39668848045 454225.7234257212 456354.56899465853 404473.0392669388 428292.47197821084 426974.3604403968 431377.2226892126 414046.9207437979 459981.928387057 1.0469463900560778 0.9544318365461109 0.987486019327933 0.9921141262981398 0.8793237610121727 0.9311071708404581 0.9282415983984362 0.9378134141092286 0.9001373645170544 1.0 18.811217656609685 -6.228928059606017 23.89961272931292 0.92635160782017 0.9917752436361471 0.44296890217268925 0.03596852723261103 348.9912188924603 256548.72551433955 0.010004274805045227 0.012914210105346385 5.90298854416897e-07 6.228928059606017 0.0654236358159771 AASAPAKES(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AASAPAKESPR 11 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 AASAPAKES(1)PR;AASAPAKES(1)PR 71.806 0.013593000000000001 1108530000.0 223281.0 239092.0 247807.0 291702.0 312965.0 300697.0 323078.0 289983.0 276764.0 234799.0 True False 261078.06329923155 262827.47365601966 253715.65869328118 275358.8826506433 251641.75488805037 284927.91997318476 292473.7129578369 282371.2535123852 280811.1499139528 277366.2000321385 0.9412756971432725 0.9475829197125164 0.9147317108713429 0.9927629344121144 0.9072545784558197 1.0272625862133529 1.0544677503024806 1.0180449293377014 1.0124202223681729 1.0 18.081432465353416 -6.776355473520985 24.99974973947882 1.0255687226839822 0.9425500628705022 0.7255770415005369 0.025078266585539754 120.46598279050859 201902.76242917238 0.008469937797420534 0.0074995491408279035 1.673572482747453e-07 6.776355473520985 -0.08301865981348 AASAPAKES(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 AASAPAKESPR 11 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 AASAPAKES(1)PR;AASAPAKES(1)PR;AASAPAKES(1)PR 70.438 0.015203 2560380000.0 125362.0 119357.0 121631.0 103264.0 105380.0 99971.0 94796.0 95998.0 105876.0 78646.0 True False 123574.31489142495 119080.63619977195 111630.96868923781 110858.37903860584 99181.75558505124 95695.47337378318 99704.07303960959 100458.41753792898 93951.12995629325 92239.85631079231 1.3397062813612213 1.2909889603312314 1.210224876252075 1.2018489996892494 1.0752592160472252 1.0374633829799944 1.0809218165265502 1.0890998919105546 1.018552431822259 1.0 16.493102645142464 -5.654104658994505 0.7256579014978375 1.0392107794056256 1.377911633776856 0.9313173887356614 0.029448024209358648 0.28702082882718927 0.24233846524935643 0.015319269720814557 0.06663947132274724 2.217661929389112e-06 5.654104658994505 0.33870085437123043 AASAPAKGT(ph)PGKGATPAPPGK ddPTM_PC-9_AZD4547_30min_R2 1 AASAPAKGTPGKGATPAPPGK 21 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 AAS(0.356)APAKGT(0.64)PGKGAT(0.004)PAPPGK 47.688 0.028124 55129000.0 273190.0 197400.0 306190.0 411970.0 421820.0 348010.0 228080.0 271100.0 230490.0 404910.0 True False 360058.7372949989 261205.68963260602 302129.7205390083 316996.6813730518 363257.57414320344 326248.8796855428 248378.67815049397 229207.7242582522 242673.23084533875 390734.2241450112 0.9214927053878242 0.6684996437262841 0.7732358771492728 0.8112846579198202 0.9296794385955541 0.834963664622487 0.635671673485951 0.5866077504723197 0.6210698112670997 1.0 18.575828100170483 -7.255417156953756 24.57941404532835 0.6763879540145514 0.8181894400026686 0.13314913759923275 0.12859302167478642 600.825088938619 2452245.762906527 0.04878422389903444 0.03674258820026637 5.553705457045545e-08 7.255417156953756 0.14180148598811715 AASDIAMTELPPTHPIR ddPTM_PC-9_Lapatinib_30min_R1 2 AASDIAMTELPPTHPIR 17 0 P62258;P62258-2;K7EM20 P62258 YWHAE 14-3-3 protein epsilon 0 ; 88.311 0.001864 4063000.0 37709.0 40401.0 50506.0 37720.0 44969.0 52106.0 46432.0 44364.0 48844.0 40113.0 False True 37171.26274501633 40307.45396673006 46353.591638797974 40494.05463023133 42324.01183245565 49877.54784501854 48836.02176647914 46425.31339874453 43342.67436987787 47046.47860278724 0.7900965991281256 0.856758149893541 0.9852722884992243 0.8607244544723966 0.8996212488036924 1.0601760073508153 1.0380377706650692 0.9867967758163751 0.9212735077543095 1.0 15.52179912179296 -6.644195088812287 6.530837268126075 1.0023253469949487 0.8802233426102342 0.5457057778242014 0.056214106613813375 0.18570729402101677 9.902893282993547 0.01975101879165338 0.019705337576665184 2.2688454380738497e-07 6.644195088812287 -0.12210200438471452 AASDPLLSS(ph)VSPAVSK ddPTM_PC-9_AZD4547_30min_R2 1 AASDPLLSSVSPAVSK 16 0 P19532 P19532 TFE3 Transcription factor E3 1 AASDPLLS(0.125)S(0.85)VS(0.024)PAVSK 266.44 5.072399999999999e-69 24374000.0 73781.0 70626.0 107080.0 132310.0 106280.0 106670.0 98657.0 133030.0 105820.0 103150.0 True False 97241.82325986434 93454.47333329497 105660.04923517081 101807.97366912264 91524.85652633742 99999.90803728889 107437.28187606673 112473.27022528708 111413.42916418833 99538.74989641637 0.9769242969301675 0.9388752966110895 1.0614966467343068 1.0227973907153516 0.9194897125147895 1.0046329508995484 1.0793513278785383 1.1299445727651878 1.1192970504464763 1.0 16.602970647922973 -7.254793605096904 3.8818278779761837 1.0948379717714647 0.9859338849904888 0.463101511201391 0.04974845829413911 0.19034460061959102 6.62753080132361 0.021264553036828688 0.015009233800100151 5.561685090121092e-08 7.254793605096904 -0.10890408678097585 AASDPLLSS(ph)VSPAVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AASDPLLSSVSPAVSK 16 0 P19532 P19532 TFE3 Transcription factor E3 1 AASDPLLS(0.206)S(0.7)VS(0.094)PAVSK 216.77 4.4142e-22 16686000.0 61146.0 75209.0 76804.0 87121.0 94564.0 88625.0 93707.0 81077.0 75565.0 61862.0 True False 71496.81011145063 82675.25248103484 78635.29864079195 82239.89282009282 76034.86303335411 83977.348984604 84830.39458007051 78948.81465818256 76669.99517006503 73077.0909006775 0.9783751546517538 1.1313429620974191 1.0760595101913522 1.1253854225241247 1.0404746836008654 1.1491610838578885 1.1608343125668135 1.0803497195240788 1.0491659455118543 1.0 16.157131582936003 -4.750643606573841 24.98808252032745 1.095955800900573 0.9783749042550368 0.3116414809051534 0.049267387729807766 536.5446825662334 1241814.3857872137 0.011870859588477129 0.16961950575925971 1.7756460248020658e-05 4.750643606573841 -0.11758089664553617 AASDPLLSS(ph)VSPAVSK ddPTM_PC-9_Lapatinib_30min_R1 4 AASDPLLSSVSPAVSK 16 0 P19532 P19532 TFE3 Transcription factor E3 1 AASDPLLS(0.034)S(0.552)VS(0.4)PAVS(0.014)K;AASDPLLS(0.185)S(0.687)VS(0.128)PAVSK;AASDPLLS(0.03)S(0.812)VS(0.158)PAVSK;AASDPLLS(0.049)S(0.795)VS(0.156)PAVSK 183.73 8.137600000000001e-08 66278300.0 216781.0 193283.0 211337.0 163749.0 210600.0 186388.0 167779.0 179535.0 198653.0 148860.0 True False 213689.6631872333 192835.46508877166 193961.68764441196 175791.64771065064 198212.9220555307 178416.61973164944 176465.77567104806 187876.85152474046 176278.60723117163 174590.2526565183 1.2239495615350162 1.1045030415767152 1.1109537027018583 1.0068812263906617 1.1353034836686253 1.021916269762545 1.0107424268307783 1.076101607426857 1.009670382790355 1.0 17.413613490238944 -1.5228787452803578 0.5229637233219881 1.0327164360569965 7.788680852832599 0.660774906849959 0.040860323083702806 72.54008107889246 0.7218545184326918 0.020555399311870056 544.2959435379427 0.0299999999999986 1.5228787452803578 6.755964416775602 AASDPLLSSVS(ph)PAVSK ddPTM_PC-9_AZD4547_30min_R2 1 AASDPLLSSVSPAVSK 16 0 P19532 P19532 TFE3 Transcription factor E3 1 AASDPLLS(0.088)S(0.287)VS(0.624)PAVS(0.001)K 209.31 2.9745e-17 25732000.0 35827.0 34196.0 47269.0 65069.0 57587.0 48905.0 49787.0 56451.0 41896.0 50925.0 True False 47219.240752106285 45249.188260773044 46642.182174984046 50068.34735602857 49592.03907397633 45846.962618952006 54217.946549801054 47727.795064930324 44110.53702762081 49142.131250363615 0.9608708363001024 0.9207819667047556 0.9491281918026079 1.0188476991554594 1.0091552362945062 0.9329461594853555 1.1032884649136963 0.9712194780843408 0.897611395869088 1.0 15.584672807002377 -5.629261265919193 6.642236198148139 0.9921948930045624 0.9394847257308158 0.1455329856951375 0.052072156677486214 0.3903761557337286 21.531191437206896 0.014320144974463845 0.02497465320190815 2.3482197373519944e-06 5.629261265919193 -0.052710167273746666 AASDPLLSSVS(ph)PAVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AASDPLLSSVSPAVSK 16 0 P19532 P19532 TFE3 Transcription factor E3 1 AASDPLLS(0.018)S(0.344)VS(0.638)PAVSK;AASDPLLS(0.035)S(0.099)VS(0.794)PAVS(0.072)K;AASDPLLS(0.078)S(0.013)VS(0.91)PAVSK 170.09 1.843e-05 37980100.0 86379.0 94925.0 101906.0 123402.0 129741.0 117037.0 116857.0 123844.0 106110.0 94097.0 True False 101001.25863698368 104348.5266625299 104335.82552065703 116488.18601468201 104319.18240356135 110899.37368813653 105787.45898858445 120593.22622356466 107661.65800960237 111156.04122855779 0.9086438984391864 0.93875713374831 0.9386428696765378 1.0479699054337526 0.9384931421681475 0.9976909258589598 0.9517022900362696 1.0849003337173753 0.9685632631359162 1.0 16.762226834080465 -2.0778667016964807 0.38954706021700763 1.0073246798923106 3.8237541093662816e-08 0.3266940090690871 0.04297823678530361 51.0356047763442 1.0489429816579932 0.03125172187317436 36.71458152156083 0.008358595298029856 2.0778667016964807 -1.0073246416547694 AASEQQADTSGGDS(ph)PKV ddPTM_PC-9_Lapatinib_30min_R1 1 AASEQQADTSGGDSPKV 17 1 U3KQ26 U3KQ26 FOXK1 1 AASEQQADTSGGDS(1)PKV 183.71 1.8991e-33 0.0 13952.0 13565.0 11051.0 9734.5 13175.0 12045.0 12232.0 10632.0 10687.0 9391.5 True False 13753.041921516562 13533.59107593111 10142.429438093624 10450.407603340049 12400.07240304661 11529.863428266397 12865.31310836434 11126.001534024244 9483.317520900913 11014.808261612861 1.2485956718326707 1.2286724157601843 0.9207994544435677 0.9487598290530598 1.1257637998349423 1.046760248060652 1.168001548715158 1.0100948895133197 0.8609607444507893 1.0 13.427156761340141 -5.2379769904324585 20.093975941157645 1.0193858616617901 1.238635409584073 0.5261358927592661 0.08638211058578389 56.613668566808514 48482.17855347619 0.02329296722530887 0.06141325382222681 5.781266766054473e-06 5.2379769904324585 0.2192495479222829 AASGEDSTEEALAAAAAPWEGGPVPGVDRS(ph)PFAK ddPTM_PC-9_AZD4547_30min_R2 2 AASGEDSTEEALAAAAAPWEGGPVPGVDRSPFAK 34 1 E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 E7ESD2 FAM21A WASH complex subunit FAM21A 1 AASGEDSTEEALAAAAAPWEGGPVPGVDRS(1)PFAK;AASGEDSTEEALAAAAAPWEGGPVPGVDRS(1)PFAK 113.91 6.6178e-24 9210800.0 12989.1 10896.2 16866.5 23892.8 19235.9 18400.8 19659.9 19790.0 15948.4 17862.9 True False 17119.36360993618 14418.183563195553 16642.83918962467 18384.684100080216 16565.327320803313 17250.195067146742 21409.593013727143 16731.910228959114 16791.399864696086 17237.525308043598 0.9931450892169377 0.8364416182447926 0.9655004933833844 1.0665500860208348 0.9610037998362436 1.0007350103264088 1.2420340293125904 0.9706677687168618 0.9741189390370708 1.0 14.073265049447498 -5.5475528542263515 5.802480929867659 1.0334145197222004 0.9110873768276398 0.2359736139996963 0.08476335895084555 0.22006522202820167 23.019378458800976 0.023479851398524706 0.042649958125906114 2.8343086732966916e-06 5.5475528542263515 -0.12232714289456059 AASGEDSTEEALAAAAAPWEGGPVPGVDRS(ph)PFAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AASGEDSTEEALAAAAAPWEGGPVPGVDRSPFAK 34 1 E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 E7ESD2 FAM21A WASH complex subunit FAM21A 1 AASGEDSTEEALAAAAAPWEGGPVPGVDRS(1)PFAK;AASGEDSTEEALAAAAAPWEGGPVPGVDRS(1)PFAK;AASGEDSTEEALAAAAAPWEGGPVPGVDRS(1)PFAK 102.21 1.0623e-16 9465800.0 37453.9 42343.0 52021.0 58295.0 72654.0 65556.0 69099.0 69490.0 58015.0 48305.0 True False 43794.10552175545 46546.53320486188 53261.377930741124 55028.92014493999 58417.97025110289 62118.12795525758 62553.44248656227 67665.96113074101 58863.35962140304 57062.31411783036 0.7674786099863242 0.8157140824808821 0.9333897293537635 0.9643653783705384 1.0237574685539947 1.0886016264077067 1.0962303834610185 1.1858257446589833 1.031562784149511 1.0 15.800250635032357 -5.522144722454499 0.789683862086134 1.095862533367645 0.718151537290858 0.8364420733384402 0.048878381432444766 0.40227225291021873 0.37625091135391137 0.021367249082910128 0.11214765456461721 3.005074737375767e-06 5.522144722454499 -0.37771099607678704 AASGEDSTEEALAAAAAPWEGGPVPGVDRS(ph)PFAK ddPTM_PC-9_Lapatinib_30min_R1 2 AASGEDSTEEALAAAAAPWEGGPVPGVDRSPFAK 34 1 E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 E7ESD2 FAM21A WASH complex subunit FAM21A 1 AASGEDSTEEALAAAAAPWEGGPVPGVDRS(1)PFAK;AASGEDSTEEALAAAAAPWEGGPVPGVDRS(1)PFAK 113.15 2.2683e-22 7880300.0 35016.0 28844.4 33339.0 26608.7 30793.0 32317.0 27395.7 25920.0 37621.0 26291.5 True False 34516.66541885205 28777.612563994673 30597.996112261637 28565.59256202111 28981.816281367304 30934.877244606472 28814.115297810404 27124.337825612176 33383.72681330716 30835.950743778347 1.119364397279573 0.9332487525068778 0.992283207562046 0.9263730117932129 0.9398710136159774 1.0032081547168799 0.9344325244657526 0.8796335825995231 1.0826235613974986 1.0 14.912325708180562 -4.7552945341490185 24.98901924956818 0.9609632133006148 1.1193646589673192 0.42193003270795004 0.0536828980345558 184.69454729135805 751017.7952564043 0.012552421345270019 0.11262547764603272 1.7567318120265427e-05 4.7552945341490185 0.15840144566670433 AASIENVLQDS(ph)SPEHCGR ddPTM_PC-9_AZD4547_30min_R2 1 AASIENVLQDSSPEHCGR 18 0 K7EPJ5;O60291-4;O60291;O60291-3;O60291-2 K7EPJ5 MGRN1 E3 ubiquitin-protein ligase MGRN1 1 AASIENVLQDS(0.5)S(0.5)PEHCGR 177.29 9.835799999999999e-09 11838000.0 31340.0 25392.0 53455.0 64981.0 49872.0 49233.0 36625.0 58493.0 45960.0 48489.0 True False 41305.468087504116 33599.46743237656 52746.151773123456 50000.63439644213 42948.13365338264 46154.45272710078 39884.55404797365 49454.25088542218 48389.35177080034 46791.41486890294 0.8827574075977617 0.7180690630217809 1.1272613132324403 1.0685856483829475 0.9178635391494754 0.9863872006523685 0.8523904258873028 1.0569086449721556 1.034150215512277 1.0 15.51395623281464 -5.253585805386324 24.998224533908804 1.0004563016488566 0.8004132334373627 0.4981916024528322 0.08218736609519907 502.92794108623116 1600829.6210954557 0.02159976081208307 0.05492751823331626 5.577174006838873e-06 5.253585805386324 -0.20004306821149387 AASIENVLQDS(ph)SPEHCGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AASIENVLQDSSPEHCGR 18 0 K7EPJ5;O60291-4;O60291;O60291-3;O60291-2 K7EPJ5 MGRN1 E3 ubiquitin-protein ligase MGRN1 1 AASIENVLQDS(0.655)S(0.345)PEHCGR;AASIENVLQDS(0.5)S(0.5)PEHCGR;AASIENVLQDS(0.5)S(0.5)PEHCGR 185.16 7.9363e-11 19308000.0 98391.0 117058.0 145656.0 120316.0 158924.0 133993.0 114451.0 118589.0 111544.0 100728.0 True False 115046.65298916935 128678.74463062879 149128.99144345633 113575.08458973488 127783.98304547998 126966.17119880457 103609.37272651636 115476.16440543193 113175.11997948414 118989.18903759077 0.9668664348390852 1.081432234906458 1.253298662253626 0.9544991902907626 1.073912546837434 1.06703955397741 0.8707461036126933 0.9704761024041519 0.9511378377722209 1.0 16.860470975445864 -7.227058236871838 18.6417171525363 0.9456300629645292 1.0706501913568283 0.33223190130447966 0.08183757228821217 33.913770011173845 18387.739955961923 0.0315625663431521 0.024439273115426673 5.928458213799471e-08 7.227058236871838 0.12502012839229903 AASIENVLQDS(ph)SPEHCGR ddPTM_PC-9_Lapatinib_30min_R1 2 AASIENVLQDSSPEHCGR 18 0 K7EPJ5;O60291-4;O60291;O60291-3;O60291-2 K7EPJ5 MGRN1 E3 ubiquitin-protein ligase MGRN1 1 AASIENVLQDS(0.506)S(0.494)PEHCGR;AASIENVLQDS(0.724)S(0.276)PEHCGR 159.77 4.0966e-06 7502500.0 71022.0 71577.0 71650.0 58256.0 63682.0 56214.0 54231.0 45406.0 75666.0 45712.0 True False 70009.21325616032 71411.2678541776 65759.21357699824 62540.340576319104 59936.34996362919 53809.85826123426 57038.81582567905 47515.72852275251 67143.69828169631 53613.258292588675 1.3058190359200417 1.3319703022796745 1.2265476054099211 1.1665088556082868 1.1179389552586585 1.0036670028068926 1.0638938509276148 0.8862682484888432 1.2523711563148558 1.0 15.710302195674364 -5.906246975437203 1.097429276870302 1.035077112525762 1.329553000219352 0.6057630518774954 0.08741152205908125 0.34339332143867446 0.8285115936863792 0.03222203925363005 0.07404436490410754 1.2409464030610515e-06 5.906246975437203 0.29447588769359 AASIENVLQDSS(ph)PEHCGR ddPTM_PC-9_AZD4547_30min_R2 2 AASIENVLQDSSPEHCGR 18 0 K7EPJ5;O60291-4;O60291;O60291-3;O60291-2 K7EPJ5 MGRN1 E3 ubiquitin-protein ligase MGRN1 1 AASIENVLQDS(0.465)S(0.535)PEHCGR;AASIENVLQDS(0.322)S(0.678)PEHCGR 171.9 2.7533e-08 8443300.0 46777.0 45984.0 69507.0 93391.0 72647.0 59577.0 60776.0 80014.0 49453.0 57089.0 True False 61651.11297795731 60847.42873386905 68585.29176493296 71861.14782656668 62561.21802849872 55851.64077189044 66184.94626128729 67649.67483880423 52066.98461969955 55090.33148653923 1.1190913416997887 1.1045028608828849 1.2449605931612717 1.3044239504009016 1.1356115735804735 1.0138192903329548 1.2013895083833162 1.2279772695746758 0.9451201910524281 1.0 15.749511523384518 -6.515635109141934 24.882116001272774 1.0968731310722972 1.19427720388993 0.22533514604152383 0.09789623348185217 587.643885727689 2018584.1762571302 0.032798334767407254 0.03409825253075471 3.0504568834691227e-07 6.515635109141934 0.09740407281763286 AASIENVLQDSS(ph)PEHCGR ddPTM_PC-9_Lapatinib_30min_R1 2 AASIENVLQDSSPEHCGR 18 0 K7EPJ5;O60291-4;O60291;O60291-3;O60291-2 K7EPJ5 MGRN1 E3 ubiquitin-protein ligase MGRN1 1 AASIENVLQDS(0.148)S(0.852)PEHCGR;AASIENVLQDS(0.091)S(0.909)PEHCGR 152.09 4.9326e-09 8752600.0 49261.9 60886.9 55457.0 39838.4 51416.6 45807.1 37264.2 35695.9 63285.0 29628.4 True False 48559.41627247392 60745.92012392998 50897.539530210626 42768.24883300654 48392.37667692497 43848.03711456553 39193.55794086905 37354.46182828973 56157.17687940623 34749.62946263861 1.3974081745154445 1.7481026722670965 1.4646930144948336 1.2307540970757465 1.3926012284232985 1.2618274724830998 1.12788419752816 1.074960004061388 1.6160510988983106 1.0 15.084709973924765 -5.630453077691536 3.898472346549975 1.2486433521242517 1.5805628997698864 0.3641401824226308 0.18052326376265143 0.2240603319804056 6.323006822400343 0.04838833272675108 0.08851167185419298 2.341784474003672e-06 5.630453077691536 0.3319195476456347 AASLDSVAT(ph)SR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AASLDSVATSR 11 0 Q9Y2J4;Q9Y2J4-2;Q9Y2J4-4;Q9Y2J4-3 Q9Y2J4 AMOTL2 Angiomotin-like protein 2 1 AAS(0.215)LDSVAT(0.774)S(0.01)R 110.81 0.0046223 6261700.0 16901.0 15144.0 29102.0 25866.0 26201.0 22495.0 22367.0 20800.0 24300.0 17100.0 True False 19762.005490034113 16647.39623679069 29795.902049949596 24416.811878703444 21067.102135452256 21315.322599815743 20248.23583694321 20254.022039421692 24655.341528916564 20200.09463647448 0.9783125200983301 0.8241246655711786 1.4750377454246357 1.2087474003520264 1.04292096223214 1.0552090464629578 1.002383216580669 1.0026696609059365 1.2205557435556478 1.0 14.30207443149942 -6.365654615337609 21.35467640302013 1.0515714019308349 1.1256472450886583 0.03765115877626635 0.16664859615496042 43.71892805542549 8924.980312587362 0.055058172088444914 0.06243011242011641 4.308691348333741e-07 6.365654615337609 0.07407584315782345 AASLNYLNQPS(ph)AAPLQVSR ddPTM_PC-9_AZD4547_30min_R2 1 AASLNYLNQPSAAPLQVSR 19 0 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 AAS(0.003)LNYLNQPS(0.997)AAPLQVSR 162.67 1.5712999999999999e-06 103220000.0 27789.0 35456.0 50642.0 56046.0 56247.0 48046.0 38429.0 53055.0 41068.0 42383.0 True False 36625.323952892555 46916.4586201301 49970.453991105 43125.46060206825 48438.07494389264 45041.67602474527 41849.106553162565 44856.56883261374 43238.77063801632 40899.184070381176 0.8955025579450688 1.1471245621769404 1.2217958652943681 1.0544332749488594 1.1843286374744837 1.1012854424488152 1.0232259519198896 1.0967595039407758 1.0572037467449003 1.0 15.319784441558612 -7.134889522758393 6.67322616047379 1.0526525251800947 1.1106963971095696 0.0844643373650461 0.0861325277393855 0.6510096456306754 32.547711309272266 0.032993077733247514 0.025520855332143887 7.330109751379143e-08 7.134889522758393 0.05804387192947491 AASLNYLNQPS(ph)AAPLQVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AASLNYLNQPSAAPLQVSR 19 0 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 AAS(0.312)LNY(0.002)LNQPS(0.685)AAPLQVSR;AAS(0.04)LNYLNQPS(0.96)AAPLQVSR 269.99 8.038399999999999e-79 102592000.0 53168.0 59078.0 66039.0 72550.0 77684.0 60838.0 71192.0 54478.0 52575.0 58790.0 True False 62168.29228413315 64942.87340709985 67613.62021430215 68485.2587102734 62462.377859260036 57647.54818082192 64448.17837455459 53048.01022421226 53343.80991287197 69448.16161861618 0.8951754925571478 0.9351273222139741 0.9735840177542976 0.986134940279187 0.8994100981719356 0.8300802618419346 0.9280040950324983 0.7638504603697426 0.7681097478982467 1.0 16.083648884284422 -6.5369551637137375 4.468138298314089 0.8482483317959113 0.9483961280905762 0.2628081870024608 0.0695698155194756 0.25021483862298005 12.435510555398103 0.02307398945094981 0.02406530508943919 2.904322479394024e-07 6.5369551637137375 0.10014779629466486 AASLNYLNQPS(ph)AAPLQVSR ddPTM_PC-9_Lapatinib_30min_R1 2 AASLNYLNQPSAAPLQVSR 19 0 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 AAS(0.269)LNY(0.258)LNQPS(0.458)AAPLQVS(0.014)R;AAS(0.062)LNYLNQPS(0.937)AAPLQVSR 157.5 1.3335e-05 194621000.0 80228.0 77681.0 86917.0 72084.0 74239.0 91653.0 70927.0 81952.0 79513.0 63104.0 True False 79083.93400798658 77501.13441720638 79771.01976932233 77385.29782517476 69872.40797948965 87733.21484357814 74599.25301152369 85759.78910048475 70557.40863099044 74011.44231920534 1.0685365874496 1.047150710601616 1.0778200946993628 1.0455855932575704 0.9440757508566802 1.1854006906822856 1.0079421596701652 1.158736898148934 0.9533310853027572 1.0 16.175460711115903 -8.301838277785356 24.998658825824638 0.9766654858567799 1.0637907273527925 0.23077412094063254 0.06570476879948588 867.7717442384069 536965.7880746793 0.059418442473318796 0.01534258564676904 4.990702962402236e-09 8.301838277785356 0.08712524149601253 AASLT(ph)EDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AASLTEDR 8 0 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 AAS(0.211)LT(0.789)EDR 112.41 0.009120999999999999 20244000.0 29393.0 62504.0 54767.0 34560.0 41030.0 27216.0 33794.0 22463.0 21057.0 22805.0 True False 34368.65436178763 68708.98404545462 56072.85298500412 32623.715245031774 32990.46603631944 25788.7450489702 30592.787672627477 21873.37005151586 21364.918789069787 26939.36597571933 1.2757781453640882 2.5505048673893285 2.0814466470941833 1.2110053100149347 1.2246192455328762 0.95728849269184 1.1356164692294912 0.8119482125611459 0.7930742990880395 1.0 14.717428276583915 -5.850249181377258 3.6784430203532157 0.9992917243721694 2.0324423713291244 0.6569019100362481 0.31641556395782006 0.1302061463310332 3.4073868775350893 0.09035896434756481 0.1433309371974053 1.4117273176705986e-06 5.850249181377258 1.0331506469569551 AASLT(ph)EDR ddPTM_PC-9_Lapatinib_30min_R1 2 AASLTEDR 8 0 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 AAS(0.212)LT(0.788)EDR;AAS(0.25)LT(0.75)EDR 117.81 0.008631999999999999 41835000.0 50909.0 67689.0 74764.0 58711.0 71137.0 69313.0 86963.0 68093.0 82632.0 65725.0 True False 50183.0283244328 67532.27027929982 68617.19251738573 63028.80279415455 66952.86152072316 66348.64456649467 91465.51862677303 71256.84936571807 73325.11400646441 77085.47867694257 0.6510049517204762 0.8760699348099105 0.890144209974403 0.8176481988041078 0.8685534898384146 0.860715217772145 1.186546677748422 0.9243874538854238 0.951218248429935 1.0 16.234171491130766 -7.0292283176689985 24.197244671686338 1.0112933719970882 0.8311696396223628 0.5124579918886485 0.09029764855521703 415.5034789820132 343981.4283685445 0.034132916504157416 0.026493636611505115 9.349140411132527e-08 7.0292283176689985 -0.18012373237472545 AASLT(ph)EDRDR ddPTM_PC-9_AZD4547_30min_R2 1 AASLTEDRDR 10 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 AAS(0.024)LT(0.976)EDRDR 125.23 0.003982 4463900.0 18014.0 15873.0 26291.0 37677.0 31838.0 23194.0 18860.0 27465.0 20753.0 22717.0 True False 23742.077285523275 21003.63683656716 25942.364161765756 28991.14975384729 27417.84326388349 21743.67551342342 20538.503463338788 23220.915332913704 21849.9612119108 21921.68474451666 1.0830407225640792 0.9581214711073183 1.1834110591456617 1.3224873038601168 1.250717888858501 0.9918797650286543 0.936903513698971 1.0592669132659627 0.9967281924978963 1.0 14.420071057371553 -6.78243298331038 24.837157474371917 0.9969065235919135 1.158741948003871 0.42510035922144873 0.0945431106706811 259.7646437977844 307320.6141180051 0.03824068755326996 0.033760509824260154 1.65031564457047e-07 6.78243298331038 0.16183542441195753 AASLTEDRDR ddPTM_PC-9_AZD4547_30min_R2 1 AASLTEDRDR 10 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 0 104.42 0.0033789000000000002 21201000.0 79298.0 47323.0 88516.0 165680.0 122530.0 98293.0 74730.0 105090.0 65750.0 73344.0 False True 104513.11449913526 62619.23429829691 87342.22000467306 127485.03573048337 105518.82452175498 92146.72317155005 81380.82522880752 88850.75522795905 69225.41076871469 70776.248884176 1.4766693085157565 0.8847492666752106 1.2340611629136626 1.8012403559153047 1.4908790192375772 1.3019441496870854 1.1498324157018507 1.255375307800808 0.9780881561270754 1.0 16.110977681018667 -7.885201560779366 1.2065976146335973 0.992723496446436 1.3578460636489234 0.280224915188792 0.22375714183118126 0.738356470017562 1.936803680212024 0.2171397528853052 0.07929576198826381 1.3025621049450217e-08 7.885201560779366 0.36512256720248737 AASLTEDRDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AASLTEDRDR 10 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 0 ;;; 114.86 0.0015199999999999999 33635000.0 92987.0 87053.4 102168.0 119881.0 139593.0 120247.0 116820.0 129683.0 121256.0 97632.8 False True 108727.86252303416 95695.48623612238 104604.07259429747 113164.45622944603 112240.75372673498 113941.03563725456 105753.9638964416 126278.95866049644 123029.13960618521 115332.85377918031 0.9427310515632236 0.8297330994630878 0.9069754988858206 0.9811987870005718 0.9731897724618386 0.9879321624643871 0.9169456961406787 1.0949088184557878 1.0667310794350102 1.0 16.815444012862308 -6.3698014294831955 0.5544198089288896 1.0434783475484506 0.8702487884999074 0.5021327342568409 0.051620346804158654 0.8765321985924173 0.5617516636033608 0.04208892603017643 0.07708579547783873 4.267746064365669e-07 6.3698014294831955 -0.1732295590485432 AASLTEDRDR ddPTM_PC-9_Lapatinib_30min_R1 2 AASLTEDRDR 10 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 0 ; 93.598 0.008674 28342000.0 125288.0 93893.0 131412.0 109469.0 103252.0 97760.0 94069.0 85059.0 116739.0 76143.0 False True 123501.3701449946 93675.59652726863 120607.8126249896 117519.7154378791 97178.92036124249 93579.03268969055 98939.43253684799 89011.15166314613 103590.62450383196 89304.21609583023 1.3829287747452843 1.0489493175411515 1.3505276446922532 1.315948121774805 1.0881784154172756 1.047868026625676 1.1078920667158474 0.9967183583766122 1.1599746241842752 1.0 16.446440666844033 -6.326546213375533 6.156322944591057 1.066365960874942 1.2636263649978066 0.5317233122932102 0.09539593122030121 0.18943891097897647 14.033307216508371 0.028748824259983503 0.03279000046833992 4.714696994681259e-07 6.326546213375533 0.1972604041228645 AASPPAS(ph)ASDLIEQQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AASPPASASDLIEQQQK 17 0 Q5VSL9-3;Q5VSL9-2;Q5VSL9 Q5VSL9-3 STRIP1 Striatin-interacting protein 1 1 AAS(0.174)PPAS(0.592)AS(0.234)DLIEQQQK;AAS(0.158)PPAS(0.841)AS(0.001)DLIEQQQK 82.48899999999999 0.0044216 54404000.0 68214.0 69335.0 64971.0 64719.0 69859.0 59307.0 64707.0 59778.0 59395.0 41809.0 True False 79761.28291208726 76218.1205809483 66520.15504388961 61093.00425182897 56170.63043702751 56196.83651599343 58577.48452188869 58208.89084002645 60263.539510699564 49388.64074013807 1.6149722226970582 1.5432317925487258 1.3468715487411416 1.2369849288477943 1.1373188165386727 1.1378494259778718 1.1860517650222122 1.1785886383530326 1.2201902827773812 1.0 15.59189164337723 -5.409122213079631 1.3197141757292492 1.1527075720700315 1.6442359490861451 0.903820024736447 0.05595691413174558 0.15662353648997268 0.4624071090028671 0.017210277521513002 0.0760730039785458 3.898322700940409e-06 5.409122213079631 0.4915283770161136 AASPPAS(ph)ASDLIEQQQKR ddPTM_PC-9_AZD4547_30min_R2 1 AASPPASASDLIEQQQKR 18 1 Q5VSL9-3;Q5VSL9-2;Q5VSL9 Q5VSL9-3 STRIP1 Striatin-interacting protein 1 1 AAS(0.064)PPAS(0.59)AS(0.346)DLIEQQQKR 70.167 0.0047122 35498000.0 43041.0 23940.0 69469.0 162650.0 112530.0 76440.0 58574.0 67451.0 48060.0 73753.0 True False 56727.142691584755 31678.136827784136 68547.79566976169 125153.55541744978 96907.15190919045 71660.19471613724 63786.97252712652 57027.99781978374 50600.35348356539 71170.92991866605 0.7970549598889938 0.44509938065985405 0.9631431786559194 1.7584926255772537 1.3616114334874603 1.0068745033685849 0.896250373572779 0.8012821791840459 0.7109694019930798 1.0 16.119000465879445 -7.308791792616222 3.1561885493776622 0.8244079431489383 1.0715813989032328 0.08512238631820312 0.32907407260398114 0.7462369985412693 14.961051984803875 0.17259398559709505 0.11410747694016819 4.911432812830271e-08 7.308791792616222 0.2471734557542945 AASPS(ph)PQSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AASPSPQSVR 10 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 AAS(0.379)PS(0.608)PQS(0.014)VR 71.268 0.033612 20181000.0 108230.0 97995.0 121390.0 140980.0 149970.0 141520.0 125980.0 130840.0 133990.0 105840.0 True False 126551.20136006089 107723.2959736071 124284.39797413867 133081.34766332654 120584.45506865263 134098.44206827827 114046.26238378443 127405.58863643947 135949.35026582456 125027.95417102116 1.0121832529304298 0.8615936866907088 0.9940528803993273 1.0644127430997505 0.9644599551209929 1.0725476790962276 0.9121661082911484 1.0190168229271834 1.0873516340182965 1.0 16.93189116800484 -5.504200078887267 24.395025113395796 1.0148661951080646 0.934622153554982 0.21869264652971976 0.059758984517809796 749.5473946685752 978933.8576053584 0.01499846743388511 0.030361746900190136 3.1318425562291593e-06 5.504200078887267 -0.08024404155308262 AASPVLLSS(ph)NSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AASPVLLSSNSQK 13 0 P41970;G3V1Z7 P41970 ELK3 ETS domain-containing protein Elk-3 1 AAS(0.173)PVLLS(0.333)S(0.49)NS(0.004)QK 96.23 0.0033159999999999995 9785400.0 34351.0 28188.0 35428.0 33255.0 44358.0 36335.0 32887.0 32518.0 34631.0 28241.0 True False 40165.94583682399 30986.31835199788 36272.73788143822 31391.830164164687 35666.368326567346 34429.528635888186 29771.705278738853 31664.436955669004 35137.41285958474 33360.86974436701 1.2039837733429002 0.9288222576160482 1.0872839395190792 0.9409775705702398 1.0691078679862542 1.0320333042786338 0.8924139420485526 0.949149023940407 1.053252302138127 1.0 15.025869281027724 -4.750110366595268 24.976934049780187 0.9946901978634523 1.2039842351951637 0.5042681060465879 0.06222691619686933 421.65793552204667 929564.3071226566 0.015285715217444094 0.23298123251737876 1.7778275560176363e-05 4.750110366595268 0.20929403733171148 AASPYSQRPAS(ph)PTAIR ddPTM_PC-9_AZD4547_30min_R2 3 AASPYSQRPASPTAIR 16 1 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 AASPYSQRPAS(0.974)PT(0.026)AIR;AASPYSQRPAS(0.981)PT(0.019)AIR;AASPY(0.022)S(0.221)QRPAS(0.743)PT(0.013)AIR 186.98 2.5619e-07 30412100.0 45364.6 49302.9 51794.0 71988.0 60770.0 62625.0 47109.0 66998.0 48777.0 53324.0 True False 59789.599157702294 65239.09825424221 51107.17771840161 55392.27880351303 52333.134466555675 58709.048850053514 51301.60973777447 56644.9985608793 51355.25263978091 51457.14299056241 1.1619300194856934 1.267833666284339 0.9931988981155642 1.0764740439179135 1.0170237099279673 1.140930985243801 0.9969774215250065 1.1008189586287054 0.9980198987961655 1.0 15.651083737364058 -5.261363189494592 24.999999999886484 1.0465198868585657 1.2148818490610882 0.6248958566888467 0.05389884480964028 3.8742454370610035 1270715.3383201421 0.01280441915701244 0.029756864037677282 5.478186464244229e-06 5.261363189494592 0.16836196220252253 AASPYSQRPAS(ph)PTAIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AASPYSQRPASPTAIR 16 1 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 AASPY(0.003)S(0.002)QRPAS(0.976)PT(0.02)AIR;AASPYSQRPAS(0.991)PT(0.008)AIR;AAS(0.007)PY(0.003)S(0.026)QRPAS(0.812)PT(0.151)AIR 121.13 0.00038781 20404600.0 29305.4 38897.5 42653.0 35293.0 51811.0 31582.7 37221.1 35854.7 32638.4 28118.2 True False 34266.22541196651 42758.986735378065 43670.00928240327 33315.64763144981 41659.00647837553 29926.44761383421 33695.24795057213 34913.55211619485 33115.67485421361 33215.80707645125 1.0316240497512994 1.287308378115327 1.3147357576436447 1.0030058145138174 1.2541922098262122 0.90097005756789 1.014434117858927 1.0511125632394231 0.9969854045091492 1.0 15.019582348942679 -6.756867651911449 24.999982295871924 0.9972533167124017 1.1820915921067616 0.4592498191442642 0.10052357465811398 109.28251295480018 597599.6011394426 0.033688944699493906 0.03262063058857497 1.7503800229525042e-07 6.756867651911449 0.18483827539435993 AASPYSQRPAS(ph)PTAIR ddPTM_PC-9_Lapatinib_30min_R1 2 AASPYSQRPASPTAIR 16 1 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 AASPYSQRPAS(0.984)PT(0.016)AIR;AASPYSQRPAS(0.793)PT(0.207)AIR 237.06 6.413599999999999e-109 7636800.0 22554.0 39133.0 29536.0 23245.4 29521.0 22769.0 23486.0 29017.0 32902.0 21352.0 True False 22232.375824102943 39042.389942824375 27107.664092257088 24954.944260381188 27784.632820519077 21795.22294713138 24701.990162119437 30365.23575176653 29196.23028658016 25042.664750248394 0.8877799565592325 1.5590349642179002 1.082459249548841 0.9964971583199294 1.1094918650876995 0.8703236322690139 0.9863962325285061 1.2125401212131526 1.165859567172881 1.0 14.61210046487996 -5.4949420902405 24.957281842245553 1.0492704930938248 1.2477423844839906 0.12938834622034245 0.1765050636709942 1152.4666284954035 1029557.3808689668 0.04438264906578778 0.09203266733261115 3.199321685679278e-06 5.4949420902405 0.19847189139016574 AASSDQLRDNS(ph)PPPAFKPEPPK ddPTM_PC-9_AZD4547_30min_R2 5 AASSDQLRDNSPPPAFKPEPPK 22 2 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 AAS(0.002)S(0.008)DQLRDNS(0.99)PPPAFKPEPPK;AAS(0.047)S(0.069)DQLRDNS(0.884)PPPAFKPEPPK;AAS(0.001)S(0.002)DQLRDNS(0.997)PPPAFKPEPPK;AAS(0.001)S(0.002)DQLRDNS(0.998)PPPAFKPEPPK;AAS(0.039)S(0.039)DQLRDNS(0.921)PPPAFKPEPPK 83.42299999999999 0.00077074 184402000.0 128895.0 103949.0 152727.0 214786.0 185371.0 158891.0 123029.0 157249.0 114577.0 178700.0 True False 169880.9288174491 137548.48141651362 150701.74018995094 165270.40611062053 159635.43638637327 148955.52065203738 133978.3426612464 132949.78027254125 120633.30630641861 172443.76739204707 0.985138120018154 0.7976425213664011 0.8739181616656164 0.9584017364621937 0.9257245930115042 0.8637918488140561 0.7769393158562212 0.7709746909569823 0.6995515589273892 1.0 17.395766461077983 -7.08467253244374 3.870475353026449 0.7933896373441955 0.9025861083292215 0.2024624882511772 0.08642567426638897 0.3322103673382782 9.230861236426502 0.03313910370385346 0.02569828755628447 8.22862872724729e-08 7.08467253244374 0.10919647098502594 AASSDQLRDNS(ph)PPPAFKPEPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 AASSDQLRDNSPPPAFKPEPPK 22 2 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 AAS(0.046)S(0.019)DQLRDNS(0.934)PPPAFKPEPPK;AAS(0.005)S(0.005)DQLRDNS(0.99)PPPAFKPEPPK;AAS(0.005)S(0.005)DQLRDNS(0.99)PPPAFKPEPPK;AAS(0.003)S(0.002)DQLRDNS(0.995)PPPAFKPEPPK;AAS(0.087)S(0.091)DQLRDNS(0.822)PPPAFKPEPPK;AAS(0.001)S(0.001)DQLRDNS(0.998)PPPAFKPEPPK 91.618 0.00089695 314015000.0 324757.0 226823.9 253056.0 374842.0 370996.0 342155.0 353945.0 376613.0 319640.0 268995.0 True False 379731.94585687225 249341.4777650674 259089.8147602248 353840.81799416116 298301.9970170694 324211.78947054705 320416.7672601101 366727.3078044588 324314.13030053116 317761.6641367523 1.1950212650367111 0.7846808029610535 0.8153589435153593 1.113541556233422 0.9387601799841148 1.0202986264920204 1.0083556433107523 1.1540955036244824 1.0206206943860885 1.0 18.277585557915337 -6.74189667002157 1.0521064105302362 1.0602432265805055 0.9443392352865853 0.06797208488153894 0.1219351554198741 1.1241404749658985 2.6616152558778325 0.06701874877322232 0.06195085034717583 1.8117711089186083e-07 6.74189667002157 -0.11590399129392026 AASSDQLRDNS(ph)PPPAFKPEPPK ddPTM_PC-9_Lapatinib_30min_R1 3 AASSDQLRDNSPPPAFKPEPPK 22 2 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 AAS(0.003)S(0.01)DQLRDNS(0.987)PPPAFKPEPPK;AAS(0.003)S(0.003)DQLRDNS(0.993)PPPAFKPEPPK;AAS(0.06)S(0.01)DQLRDNS(0.93)PPPAFKPEPPK 88.244 0.00060236 43533000.0 107659.0 97139.0 109796.0 102715.0 102674.0 101720.0 89081.0 86159.0 111497.0 83954.0 True False 106123.76291775721 96914.08061370245 100768.99670481631 110269.00374719557 96634.91718485077 97369.67272090142 93693.17830331936 90162.2616788933 98939.03374453915 98465.33703832662 1.0777778872218722 0.9842456597287597 1.023395640900442 1.1198763652662307 0.9814105155323505 0.9888725885638444 0.951534632607313 0.9156751440742905 1.0048107965753283 1.0 16.587328318493064 -6.494377495841951 23.547085270999304 0.967787332071941 1.045300953563779 0.4616613753198666 0.040812554682918625 323.57823447464307 267333.00082042726 0.01287561870837039 0.014562784535770572 3.203483593828376e-07 6.494377495841951 0.07751362149183794 AASSLNLS(ph)NGETESVK ddPTM_PC-9_AZD4547_30min_R2 4 AASSLNLSNGETESVK 16 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6;E7EN19 C9J840;O95819-6;E7EN19 MAP4K4 1 AASSLNLS(0.982)NGET(0.017)ES(0.001)VK;AASSLNLS(0.999)NGET(0.001)ESVK;AASSLNLS(1)NGETESVK;AASSLNLS(1)NGETESVK 250.38 1.8870999999999998e-47 60685300.0 132927.0 130091.0 155184.0 203876.0 188337.0 183442.0 157134.0 197534.0 153619.0 170169.0 True False 175195.02094663863 172140.3716818405 153126.15876457584 156875.53805280052 162189.65848325958 171971.34274094275 171118.62159110676 167009.65917974745 161738.98672059574 164211.43510541218 1.0668868512973884 1.0482849234667397 0.9324938830616737 0.9553265151851177 0.9876879669137856 1.047255586254083 1.0420627618366567 1.017040372812886 0.9849435066246799 1.0 17.325195069247094 -6.7281954006267775 24.95492301106174 1.0208131583830915 0.9948969779424042 0.05343312490858365 0.0405333890415631 552.1222368265393 414455.34597193974 0.014810008094175854 0.014809319350785298 1.8698406600824799e-07 6.7281954006267775 -0.02591618044068733 AASSLNLS(ph)NGETESVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AASSLNLSNGETESVK 16 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6;E7EN19 C9J840;O95819-6;E7EN19 MAP4K4 1 AASS(0.022)LNLS(0.977)NGET(0.001)ESVK;AASS(0.246)LNLS(0.754)NGETESVK;AASSLNLS(0.975)NGET(0.024)ES(0.001)VK 286.85 1.3278999999999998e-96 26528200.0 81460.0 75578.0 97810.0 87521.0 103868.0 104955.0 93901.0 90944.0 77232.0 63885.0 True False 95249.56909166195 83080.88436239876 100142.16134649068 82617.48211691028 83515.81102267696 99450.97503728197 85006.01749563207 88556.81636313292 78361.37189141074 75466.8447866182 1.2621379542364495 1.100892512431243 1.3269689706737007 1.0947520378056144 1.1066556612883067 1.3178101631051182 1.1264021668851507 1.173453277575424 1.038354950614098 1.0 16.203555336997653 -8.297738797849036 1.9698837946749823 0.9964705189370792 1.1908290305202558 0.4069196679711743 0.08267284791303578 0.3190584388384218 2.3364429336547814 0.07455379013406689 0.021632793230262647 5.0380352536818535e-09 8.297738797849036 0.19435851158317663 AASSLNLS(ph)NGETESVK ddPTM_PC-9_Lapatinib_30min_R1 4 AASSLNLSNGETESVK 16 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6;E7EN19 C9J840;O95819-6;E7EN19 MAP4K4 1 AASSLNLS(1)NGETESVK;AASSLNLS(0.994)NGET(0.006)ESVK;AASSLNLS(1)NGETESVK;AASSLNLS(0.974)NGET(0.026)ESVK 250.38 1.8870999999999998e-47 59945000.0 211786.0 181745.0 177029.0 167213.0 159714.0 155399.0 137281.0 115253.0 173025.0 119880.0 True False 208765.89280320462 181324.18061887962 162474.35897170161 179510.40182621605 150319.9365298053 148752.94702276212 144388.73845890822 120608.0751317623 153537.10246597568 140601.09826994082 1.4848098298805166 1.2896355921114808 1.1555696290491715 1.2767354169707341 1.069123487507937 1.0579785567333941 1.0269389089813188 0.8578032221356209 1.092005001064778 1.0 17.10124833813893 -3.0697298396988764 0.33489000677648867 0.9584118501923773 2.969278361966893 0.8000039827075328 0.075563355886983 8.940731944117138 0.3233921492806586 0.06975016765801642 9.167663915516302 0.0008516676678737665 3.0697298396988764 2.0108665117745157 AASSPDGFFWT(ph)QGSPKPGTASPK ddPTM_PC-9_AZD4547_30min_R2 1 AASSPDGFFWTQGSPKPGTASPK 23 1 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 AAS(0.011)S(0.039)PDGFFWT(0.95)QGSPKPGTASPK 82.859 5.8995e-05 21621000.0 42028.0 40109.0 50884.0 75306.0 62739.0 59327.0 45073.0 55494.0 50074.0 47050.0 True False 55392.0297632937 53073.449875755796 50209.24491298504 57945.365166101954 54028.77280396967 55617.27331141121 49084.40968202911 46918.67742525808 52720.80941190291 45402.793820905434 1.220013684219335 1.168946785193612 1.105862452232323 1.2762510913903578 1.1899878456178274 1.2249746905619403 1.0810878703994753 1.033387452109933 1.1611798520563275 1.0 15.470493454765027 -7.2975569536529585 8.293123030551952 1.0713648789530892 1.1953991031047126 0.5581719709753797 0.05608528378618193 0.2613793979975689 55.52938582780698 0.02304739631291072 0.01564048482206593 5.0401451798591905e-08 7.2975569536529585 0.12403422415162346 AASSPDGFFWT(ph)QGSPKPGTASPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AASSPDGFFWTQGSPKPGTASPK 23 1 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 AAS(0.033)S(0.159)PDGFFWT(0.724)QGS(0.052)PKPGT(0.022)AS(0.009)PK 57.537 0.005501300000000001 11963000.0 12662.0 9702.4 9880.2 10750.0 14039.0 12444.0 12969.0 12852.0 11459.0 9218.0 True False 14805.426514100469 10665.590151072234 10115.781438867167 10147.712351970235 11288.158729804747 11791.414733589996 11740.482432571052 12514.648617819608 11626.566196701853 10889.150430352145 1.3596493692319829 0.9794694470693724 0.9289780229934826 0.9319103833559647 1.0366427392113544 1.082859017240032 1.078181673369662 1.1492768602899075 1.0677202295134296 1.0 13.410603779175446 -6.74900802522908 5.586437922545141 1.0853685168492029 1.0302187142386405 0.0006486252368939072 0.11948347973058751 0.6676848350996746 65.21693573045869 0.04200322039199648 0.039997198406100665 1.7823458315800256e-07 6.74900802522908 -0.05514980261056235 AASSSS(ph)PGSPVASSPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AASSSSPGSPVASSPSR 17 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 AAS(0.003)S(0.002)S(0.002)S(0.613)PGS(0.38)PVASSPSR 201.4 8.428799999999999e-13 8172000.0 7243.6 7997.0 19690.0 9530.0 10191.0 12478.0 13526.0 10984.0 13786.0 8244.8 True False 8469.798412378625 8790.889309668199 20159.484274740837 8996.064996676872 8194.146706705613 11823.631713736419 12244.719360240268 10695.681638509996 13987.594169450364 9739.516974199107 0.8696322861612044 0.9026001323223819 2.0698648945471527 0.92366644264888 0.8413298861137236 1.213985431213717 1.257220393236921 1.0981737253340036 1.4361691864704185 1.0 13.249634509104464 -10.587712627401105 12.300883096982663 0.9999790263054524 1.1807284717514108 0.02302810405093192 0.34999919424204756 0.0 0.0 0.3409930610352381 0.08270296519123392 2.5839694372890644e-11 10.587712627401105 0.1807494454459584 AASSSSPGS(ph)PVASSPSR ddPTM_PC-9_AZD4547_30min_R2 1 AASSSSPGSPVASSPSR 17 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 AAS(0.001)S(0.011)S(0.044)S(0.182)PGS(0.762)PVASSPSR 101.3 0.0010747 6427400.0 9126.8 9769.0 20041.0 32575.0 17625.0 13873.0 15123.0 27890.0 15722.0 13493.0 True False 12028.932550766833 12926.63820679295 19775.243245443216 25065.337028733058 15178.072979645274 13005.51911691485 16468.917702867042 23580.24134844211 16553.032822900856 13020.614176949564 0.9238375692032785 0.9927825240131161 1.5187642438903837 1.9250502847328281 1.1656956249049346 0.9988406798765731 1.264834168270036 1.8109930167646229 1.2712943182207752 1.0 13.668509880982434 -5.208494524064572 7.114667358598458 1.3938025156512701 0.9527697655692384 0.23434168447424986 0.2947527942845663 0.3779259322373538 43.072223615237895 0.07886165032403185 0.21049127410719629 6.187361290286628e-06 5.208494524064572 -0.4410327500820317 AASSSSPGS(ph)PVASSPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AASSSSPGSPVASSPSR 17 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 AAS(0.002)SS(0.012)S(0.32)PGS(0.666)PVASSPSR;AAS(0.005)S(0.01)S(0.097)S(0.277)PGS(0.611)PVASSPSR;AASS(0.003)S(0.114)S(0.114)PGS(0.762)PVAS(0.008)SPSR 240.5 7.929e-38 32597800.0 110516.0 100785.0 143062.0 122023.0 157110.0 153675.0 146664.0 137867.0 134797.0 124371.0 True False 129224.17600950305 110790.2687351395 146473.14064565636 115186.4469139039 126325.423323572 145616.01247062397 132770.92416459252 134248.13733216096 136768.15111413048 146918.47777970598 0.8795638095520272 0.7540934973561446 0.9969688146734179 0.7840160656076083 0.8598334616084722 0.9911347753613745 0.9037047359262276 0.9137593811273806 0.9309118443168516 1.0 17.16465632795331 -6.668559985532157 8.325403347294023 0.939602702216547 0.8526610450353478 0.32440946775588175 0.06658221116473323 0.33086661201718404 26.28119995281991 0.021159053908648248 0.02113165254889034 2.1450628154330879e-07 6.668559985532157 -0.08694165718119917 AASSSSPGS(ph)PVASSPSR ddPTM_PC-9_Lapatinib_30min_R1 3 AASSSSPGSPVASSPSR 17 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 AASSS(0.005)S(0.148)PGS(0.847)PVASSPSR;AASSSS(0.015)PGS(0.978)PVAS(0.007)SPSR;AAS(0.092)S(0.005)S(0.038)S(0.128)PGS(0.736)PVASSPSR 231.21 1.2322e-29 29494200.0 32546.6 27914.8 30175.800000000003 24504.4 35602.2 36543.4 37779.0 34987.6 43549.0 33184.4 True False 32082.47951568454 27850.164995680207 27694.862205956502 26306.53532028208 33508.14859261829 34980.52396882608 39735.01176593331 36613.25162451344 38644.05302869974 38920.27932456643 0.8243126738156301 0.7155695046130159 0.7115792251900809 0.6759081840319021 0.8609431682949918 0.8987737132386513 1.020933365728766 0.9407242769042309 0.9929027668696011 1.0 15.248234443695214 -6.65701444172863 1.9488947918000774 0.9803490642948548 0.7301508465982776 0.8573430048685591 0.04611373845137039 0.11536071938429325 0.8990543335468271 0.01784523609343941 0.017612033455401556 2.2028532096769087e-07 6.65701444172863 -0.25019821769657724 AASSSSPGSPVAS(ph)SPSR ddPTM_PC-9_AZD4547_30min_R2 1 AASSSSPGSPVASSPSR 17 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 AASSS(0.001)S(0.005)PGS(0.025)PVAS(0.774)S(0.188)PS(0.007)R 73.80199999999999 0.010172 2778300.0 7336.0 6064.7 6613.3 11421.0 9201.5 5901.9 8795.5 11030.0 8844.1 7721.4 True False 9668.695401720812 8024.995673327583 6525.603320946546 8788.064902691025 7924.030554451402 5532.853260010074 9578.282460858756 9325.566944184884 9311.581070412 7451.0761362112435 1.2976240243650488 1.0770250533781511 0.875793402409751 1.1794356603044482 1.0634746457550825 0.7425576062927528 1.2854898119091243 1.2515731652323163 1.24969613787181 1.0 12.86323308933163 AASSSSPGSPVAS(ph)SPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AASSSSPGSPVASSPSR 17 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 AASSSSPGS(0.004)PVAS(0.487)S(0.487)PS(0.023)R 81.65100000000001 0.004961999999999999 4262200.0 9685.9 12877.0 14666.0 12261.0 18860.0 15945.0 15053.0 15764.0 16438.0 12914.0 True False 11325.531564754834 14155.34345887175 15015.693061114729 11574.05592069833 15164.518387642824 15108.816130431735 13627.07086571764 15350.211703338637 16678.37465235929 15255.205972832257 0.7424043690346945 0.9279024802471213 0.9842995950271617 0.758695486728293 0.9940553024750411 0.9904039419289896 0.8932734759521349 1.0062277579650891 1.0932906892284202 1.0 13.897014038586148 -1.9456115474671145 0.21884263474775734 1.03929168384099 8.430413328729992e-16 0.4235375380801557 0.08076138531966086 46.11622743045459 0.6913659440927055 0.1316940907510972 16.265126217575 0.011334136862048193 1.9456115474671145 -1.0392916838409891 AASSSSPGSPVASS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 2 AASSSSPGSPVASSPSR 17 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 AASSSSPGSPVAS(0.23)S(0.76)PS(0.009)R;AASSSSPGSPVAS(0.036)S(0.962)PS(0.001)R 263.04 3.8117999999999994e-69 23131000.0 33625.0 30956.0 54568.0 81936.0 66003.0 54246.0 49215.0 72476.0 52242.0 57467.0 True False 44317.050556551614 40961.92162242629 53844.392665902174 63046.92109858083 56839.62274471069 50853.9890446308 53595.03965791188 61276.49953279634 55003.40546584319 55455.09782159344 0.7991519679421641 0.7386502455411105 0.970954786503612 1.1369003675985085 1.0249665941906991 0.9170300124297854 0.9664583016395424 1.1049750508047276 0.9918548091430043 1.0 15.759032468680862 -5.341863782686276 4.650325154798217 1.020259458189111 0.7689715531173696 0.7187349063117769 0.06179440393050152 0.10898539105951159 4.224243899569734 0.017291928389676074 0.038322440355207474 4.551307904277115e-06 5.341863782686276 -0.25128790507174126 AASSSSPGSPVASS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AASSSSPGSPVASSPSR 17 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 AASSSSPGSPVAS(0.147)S(0.853)PSR;AASSSSPGSPVAS(0.003)S(0.995)PS(0.002)R;AASSSSPGSPVAS(0.005)S(0.995)PSR 241.66 3.7026999999999993e-38 22331200.0 60695.0 62122.0 79400.0 84139.0 95733.0 90953.0 87622.0 82748.0 78567.0 63936.0 True False 70969.46471910665 68289.06161000459 81293.19712617685 79424.96461231829 76974.80587509071 86183.26456639433 79321.80983165534 80575.95267875314 79715.89374083895 75527.09068290243 0.9396557457385616 0.9041664519650779 1.0763448769327444 1.0516089510951896 1.019168157797398 1.1410907501816987 1.0502431526812661 1.0668483579891639 1.0554609348786257 1.0 16.204706594631215 -5.26206740105607 24.999985914116845 1.061116249306271 0.9219110892728146 0.6926641934318172 0.036091370788200836 26.48136622522622 1054210.360291695 0.009032635124203504 0.020770233651159473 5.469310744271309e-06 5.26206740105607 -0.1392051600334563 AASSSSPGSPVASS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 2 AASSSSPGSPVASSPSR 17 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 AASSSSPGSPVAS(0.004)S(0.993)PS(0.003)R;AASSSSPGSPVAS(0.048)S(0.95)PS(0.002)R 223.68 7.240000000000002e-29 18104100.0 51589.0 43809.0 55532.0 45755.0 53600.0 51211.0 48546.0 44544.0 62554.0 37317.3 True False 50853.331399736075 43707.562952116954 50966.373319719016 49119.97533420558 50447.353381654524 49020.82490867168 51059.47434259771 46613.67685586684 55508.50979717754 43767.54558282337 1.1618958916374222 0.9986295180616672 1.1644786711485333 1.1222922071618926 1.1526201140566734 1.1200268202361792 1.1666058414442153 1.0650283500055449 1.2682573139070867 1.0 15.417573861658157 -5.326127717547283 24.999978398346688 1.1358750439019019 1.0802579483003307 0.06968667225609071 0.07537436319749652 428.9783629758172 165785.27111894096 0.017894132976053443 0.037249633887431896 4.719242371295087e-06 5.326127717547283 -0.05561709560157113 AAST(ph)DLGAGETVVGK ddPTM_PC-9_Lapatinib_30min_R1 1 AASTDLGAGETVVGK 15 0 H7C207;Q15032-2;Q15032-4;Q15032;Q15032-3 H7C207 R3HDM1 R3H domain-containing protein 1 1 AAS(0.247)T(0.753)DLGAGETVVGK 198.81 1.6301e-09 3435800.0 15071.0 9164.6 20434.0 14524.0 18190.0 20682.0 16566.0 15756.0 23088.0 26038.0 True False 14856.084776317082 9143.379931771342 18753.995397521045 15592.14341064368 17120.09996291597 19797.47907209676 17423.70642193948 16488.081280105904 20487.58631258168 30538.633606545885 0.48646854891152413 0.29940370121246945 0.6141072203538658 0.5105710887896943 0.5606046486391034 0.6482765184311723 0.5705463658401779 0.5399089393630147 0.6708743611957221 1.0 14.89834789246482 -14.522878745272877 0.1241415722000985 2.5212999447873568 0.3330258517316351 0.7814870390281277 0.07875498691879697 69.35947192206343 0.5500330512312414 26.297160762043752 0.7004193137685973 3.0000000000515377e-15 14.522878745272877 -2.1882740930557216 AASVAAATT(ph)SPTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AASVAAATTSPTPR 14 0 Q9Y2D9 Q9Y2D9 ZNF652 Zinc finger protein 652 1 AASVAAAT(0.063)T(0.565)S(0.373)PTPR;AASVAAAT(0.141)T(0.716)S(0.141)PT(0.002)PR 158.89 0.0010609000000000003 35752000.0 108836.0 99555.0 116059.0 117844.0 131860.0 115483.0 112563.0 106379.0 121895.0 85858.0 True False 127259.78519101584 109438.16246392627 118826.28671620831 111241.58273540298 106022.97956493002 109426.8681837974 101900.21775445249 103586.6639678672 123677.48377231596 101423.37574844612 1.2547382124871302 1.0790230719135074 1.1715867849925004 1.0968041826108048 1.0453505297229704 1.0789117141515958 1.0047015000485593 1.02132928630562 1.2194179385141475 1.0 16.630030673028074 -1.522878761484663 0.5940988450420162 1.0623576545807834 11.312046499123506 0.37977557446526766 0.0670117747913654 181.59398576656505 1.4364253639542064 0.03005200869166083 2411.8001642580657 0.02999999888064487 1.522878761484663 10.249688844542723 AASVAAATT(ph)SPTPR ddPTM_PC-9_Lapatinib_30min_R1 1 AASVAAATTSPTPR 14 0 Q9Y2D9 Q9Y2D9 ZNF652 Zinc finger protein 652 1 AASVAAAT(0.121)T(0.865)S(0.014)PTPR 109.83 0.0013503 8355500.0 46623.0 48842.0 54695.0 42874.0 44384.0 55466.0 43843.0 48286.0 44709.0 39749.0 True False 45958.14747038894 48728.90934984352 50198.18822880561 46027.09698347128 41773.42038230139 53093.848477561136 46112.976014553424 50529.54383670944 39673.40161335822 46619.56168778676 0.9858125174615039 1.0452459779905945 1.076762337771107 0.9872914999011951 0.8960491877220942 1.1388748961891353 0.9891336242793108 1.0838699894929944 0.851003316570257 1.0 15.508647820013032 -8.256001218582245 24.948226145394553 0.9255016588051513 1.0247492528263225 0.23657232374787196 0.07176123396141225 570.3927863091691 2616779.1129646245 0.049961454242066515 0.017645823616104457 5.546241567417338e-09 8.256001218582245 0.09924759402117111 AASVAAATTS(ph)PTPR ddPTM_PC-9_AZD4547_30min_R2 3 AASVAAATTSPTPR 14 0 Q9Y2D9 Q9Y2D9 ZNF652 Zinc finger protein 652 1 AASVAAAT(0.025)T(0.117)S(0.853)PT(0.005)PR;AAS(0.001)VAAAT(0.024)T(0.103)S(0.87)PT(0.002)PR;AASVAAAT(0.01)T(0.033)S(0.947)PT(0.01)PR 159.41 8.887200000000001e-05 56059800.0 190927.0 177250.0 231552.0 275986.0 276218.0 241832.0 193772.0 306582.0 214533.0 244126.0 True False 251637.81447169487 234542.5961873321 228481.46918661078 212361.69164119463 237869.89856973954 226710.2068104778 211017.33261389608 259206.79645349886 225872.77640219996 235579.22304617098 1.0681664164516604 0.9955996677235168 0.969871053279732 0.9014449105283535 1.0097235889224392 0.9623522986407211 0.8957382993513777 1.1002956589371937 0.9587975267153815 1.0 17.845852780455644 -7.759527201422605 24.999966277207854 1.022159923200384 0.9710646344634716 0.12757652296646105 0.057214156138152936 101.16346143896881 1322680.459876616 0.02823286755930404 0.015248338405597797 1.739693731361595e-08 7.759527201422605 -0.05109528873691238 AASVAAATTS(ph)PTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AASVAAATTSPTPR 14 0 Q9Y2D9 Q9Y2D9 ZNF652 Zinc finger protein 652 1 AASVAAAT(0.003)T(0.017)S(0.973)PT(0.007)PR;AAS(0.002)VAAAT(0.005)T(0.035)S(0.957)PT(0.001)PR 117.48 0.0001295 40712000.0 83212.0 92167.0 119676.0 115519.0 135745.0 98346.0 114216.0 102608.0 84246.0 73500.0 True False 97298.14808808455 101316.73064951695 122529.5297137576 109046.84494765103 109146.7417036359 93188.56263176168 103396.63362776887 99914.6487221627 85477.9383722266 86824.96817431998 1.1206240570424095 1.166907777565799 1.4112245853952168 1.2559387839764686 1.2570893373032987 1.0732922175642543 1.1908629027099402 1.150759405077608 0.9844856861981347 1.0 16.405822356337247 -7.862264206111834 0.7825575549821604 0.9866303838945436 1.2407841078170436 0.4925788205024175 0.08674458797595222 0.5673648794243527 0.6676653081139514 0.08523903321881426 0.037506237177916305 1.373206321097468e-08 7.862264206111834 0.2541537239225 AASVAAATTS(ph)PTPR ddPTM_PC-9_Lapatinib_30min_R1 2 AASVAAATTSPTPR 14 0 Q9Y2D9 Q9Y2D9 ZNF652 Zinc finger protein 652 1 AASVAAAT(0.018)T(0.151)S(0.812)PT(0.018)PR;AASVAAAT(0.009)T(0.126)S(0.864)PT(0.001)PR 159.41 0.00045005 72461000.0 255690.0 273370.0 313940.0 268090.0 245570.0 270470.0 252430.0 243600.0 268730.0 211740.0 True False 252043.8137121968 272737.0285608028 288129.065043445 287806.23292202305 231126.05540919607 258902.62859636464 265499.5902505237 254918.5453055212 238462.79754764715 248338.97687418418 1.0149184670269846 1.0982449553175835 1.160224901745567 1.1589249361683331 0.9306877974547318 1.0425372281674992 1.0691015707334317 1.026494304334154 0.9602310541387927 1.0 17.921951185126233 -6.2496006152309045 24.992956827193865 1.011264446194227 1.1111006873339941 0.47554935487712213 0.05281628923423451 737.6094331715 1557175.8170365985 0.016484237063149956 0.021122136730620394 5.628587019244209e-07 6.2496006152309045 0.09983624113976708 AASVECIS(ph)PVSPR ddPTM_PC-9_AZD4547_30min_R2 1 AASVECISPVSPR 13 0 Q5T7I8;Q92529-2;Q92529 Q5T7I8 SHC3 SHC-transforming protein 3 1 AASVECIS(0.986)PVS(0.014)PR 113.37 0.00035244 3720800.0 2221.7 2861.4 6562.3 10796.0 8889.1 5565.0 4833.9 6730.4 2838.8 6402.6 True False 2928.1543857692395 3786.2915922732464 6475.279614269354 8307.148996537282 7655.001902034881 5217.0196702682315 5264.107735494876 5690.371329205986 2988.8531724749378 6178.446922799767 0.47393049132844933 0.6128225490294389 1.0480432534548791 1.3445367582397054 1.238984812475497 0.8443901413179311 0.8520114846449862 0.9210035143633459 0.4837547703850043 1.0 12.593028517878565 -11.47966277557533 6.835047633003433 1.0548225254817893 0.891771348210372 0.013704743825870835 0.2781251340196915 0.21993830854792368 0.0013906035180534773 0.2549085574595214 0.0713516201050282 3.3138834065360984e-12 11.47966277557533 -0.16305117727141738 AAT(ph)ASPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AATASPTR 8 0 Q9NPY3 Q9NPY3 CD93 Complement component C1q receptor 1 AAT(0.613)AS(0.378)PT(0.009)R 78.264 0.032331 0.0 59616.0 55404.0 63286.0 70341.0 81718.0 69987.0 68754.0 70611.0 60133.0 53206.0 True False 69707.81133032807 60904.14296772001 64794.978253491514 66400.02181859905 65705.9445175715 66316.75851492792 62241.123384145976 68757.53606853876 61012.33136454076 62851.826621535765 1.1090817097500734 0.9690115027914177 1.0309163907623002 1.0564533345773521 1.045410261713186 1.0551285790667047 0.9902834448859035 1.0939624154849852 0.9707328274153179 1.0 15.939667052907046 -8.293123497485864 24.997253535681374 0.9853663929405565 1.039931557447641 0.24749819438975085 0.04029784273495299 1093.6366552071156 862817.2838042505 0.036221899485670124 0.00935608378750412 5.0918605655429094e-09 8.293123497485864 0.054565164507084596 AAT(ph)PLPSLR ddPTM_PC-9_AZD4547_30min_R2 1 AATPLPSLR 9 0 Q9Y3Q8 Q9Y3Q8 TSC22D4 TSC22 domain family protein 4 1 AAT(0.978)PLPS(0.022)LR 80.916 0.043991 13268000.0 42663.0 47284.0 75061.0 111430.0 79551.0 68726.0 68127.0 118720.0 92692.0 93276.0 True False 56228.9465544732 62567.62831098348 74065.64209601386 85741.53507633849 68506.71680021333 64428.55235558927 74190.17102051347 100374.5519142004 97591.50988553141 90010.43563100495 0.6246936386907632 0.6951152704946076 0.8228561674742217 0.9525732708131013 0.7610974918625495 0.7157898070809497 0.8242396617727064 1.1151434965350333 1.0842243924427257 1.0 16.457804653884175 -7.687833195913056 4.954542341461561 1.07471668743954 0.7708690396169913 0.7138904011551903 0.08613849263170237 0.11733619632012836 5.253548489168679 0.04687598243665017 0.025790061900102215 2.0519501417451596e-08 7.687833195913056 -0.3038476478225487 AAT(ph)PLPSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AATPLPSLR 9 0 Q9Y3Q8 Q9Y3Q8 TSC22D4 TSC22 domain family protein 4 1 AAT(1)PLPSLR 104.75 0.0025835000000000003 0.0 29301.0 47708.0 125900.0 74820.0 106760.0 107440.0 63779.0 78915.0 85826.0 58965.0 True False 34261.08057887046 52444.13494881209 128901.93347840908 70628.07796971274 85841.14438307239 101805.65726268961 57737.39140002693 76843.5648673542 87081.04288316001 69654.88773331685 0.49186900867665795 0.7529139254319316 1.8505798756280758 1.0139716000996497 1.232377901630203 1.4615723400842497 0.8289065316002279 1.1032042024324291 1.2501784974022434 1.0 16.08793697087141 -5.015569723969117 23.984242588410744 1.215530008763688 0.5571297104425921 0.4535759676514476 0.2680936902141126 307.22011456017384 473262.915237395 0.0663590447917882 0.18937581167998122 9.647844076997963e-06 5.015569723969117 -0.6584002983210959 AAT(ph)SPALFNR ddPTM_PC-9_Lapatinib_30min_R1 1 AATSPALFNR 10 0 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 1 AAT(0.774)S(0.226)PALFNR 86.189 0.018441 0.0 54007.0 41724.0 47445.0 42558.0 36062.0 38274.0 37799.0 37850.0 38789.0 29251.0 True False 53236.85027632916 41627.39064151492 43544.25524299627 45687.857289326224 33940.90406061989 36637.11024105171 39756.04726807257 39608.649178218366 34420.17435372189 34306.99637549247 1.5517782347847688 1.2133790491566274 1.2692529175798823 1.3317358590437192 0.9893289313099383 1.06791949490582 1.1588320595874924 1.1545356155548838 1.003298976599137 1.0 15.066215201047758 -1.5228787452804327 0.37221720239391254 1.053680661724405 7.04255306778857 0.6933406015364962 0.09325713539922205 40.98274883091222 0.5647801741491107 0.07550593233709028 175.83103276065836 0.02999999999999343 1.5228787452804327 5.988872406064165 AAT(ph)SPGVGQSAPGTR ddPTM_PC-9_AZD4547_30min_R2 1 AATSPGVGQSAPGTR 15 0 Q6IE81-2;Q6IE81 Q6IE81-2 JADE1 Protein Jade-1 1 AAT(0.592)S(0.408)PGVGQSAPGTR 113.43 0.00052543 4413600.0 15195.0 15809.0 19836.0 26339.0 19889.0 22254.0 20512.0 22781.0 19232.0 18532.0 True False 20026.69392436584 20918.95008815536 19572.961679387845 20266.950483493485 17127.75565912993 20862.45386202143 22337.52826299073 19260.719905301532 20248.564257093847 17883.2003207018 1.1198607388624233 1.1697542784855652 1.0944887563961334 1.13329550192603 0.9577567410740594 1.166595099752409 1.2490789043576584 1.0770286950823393 1.1322673735110977 1.0 14.126317319295037 -5.273381216383405 23.829836637482156 1.1076888629352328 1.1448075117527756 0.042306190505807306 0.07820255564157075 1499.1667535611816 2991583.03520023 0.02095602097583324 0.044291875160730715 5.328669485048875e-06 5.273381216383405 0.03711864881754279 AAT(ph)SPGVGQSAPGTR ddPTM_PC-9_Lapatinib_30min_R1 1 AATSPGVGQSAPGTR 15 0 Q6IE81-2;Q6IE81 Q6IE81-2 JADE1 Protein Jade-1 1 AAT(0.599)S(0.401)PGVGQSAPGTR 143.93 0.00025213 3676000.0 9607.0 17219.0 14861.0 16118.0 19534.0 19138.0 18239.0 14918.0 18765.0 14861.0 True False 9470.002418291971 17179.13046343221 13639.185945118928 17303.371488071796 18385.04852532163 18319.51235285698 19183.326175887603 15611.144740836506 16651.488095789817 17429.704048962212 0.5433254857161977 0.9856237613199795 0.7825253892323561 0.9927518814699589 1.0548112850152667 1.051051257175405 1.1006111246639214 0.8956632136141184 0.9553511665495702 1.0 14.089260452700975 -4.381996737541953 1.204544119572277 0.997474511930347 5.317314964609082e-40 0.6629832200383363 0.09067782330219733 2.2565317947702566 1.468054692414368 0.02775528933827446 3.5521050265013274 4.149571598170508e-05 4.381996737541953 -0.997474511930347 AATAARPPAPPPAPQPPS(ph)PTPSPPRPTLAR ddPTM_PC-9_AZD4547_30min_R2 3 AATAARPPAPPPAPQPPSPTPSPPRPTLAR 30 2 Q96B36-3;Q96B36;H9KV91 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 AATAARPPAPPPAPQPPS(0.322)PT(0.274)PS(0.322)PPRPT(0.082)LAR;AATAARPPAPPPAPQPPS(0.944)PT(0.052)PS(0.003)PPRPTLAR;AAT(0.001)AARPPAPPPAPQPPS(0.802)PT(0.151)PS(0.038)PPRPT(0.009)LAR 85.79799999999999 3.2427e-08 115620000.0 59761.0 53561.5 67081.0 78626.0 64860.0 68455.0 73782.0 86537.0 71581.0 71121.0 True False 78763.7548939801 70874.20742278032 66191.46211005331 60499.99045959065 55855.30856509463 64174.498028429756 80348.45506532652 73164.69507243221 75364.62552449212 68631.07543754755 1.1476398175583453 1.0326839113467479 0.9644532260067202 0.8815247331311896 0.8138486568802419 0.9350647300700808 1.1707299434414584 1.0660578259335325 1.0981122624702555 1.0 16.066574341199626 -7.244093562398109 24.721859547963323 1.089229829850091 0.9553707086878298 0.29269469883138943 0.09172860181961606 921.1445257484019 1312849.2411551753 0.03853498837859979 0.02976782246252727 5.700414519526874e-08 7.244093562398109 -0.13385912116226129 AATAARPPAPPPAPQPPS(ph)PTPSPPRPTLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AATAARPPAPPPAPQPPSPTPSPPRPTLAR 30 2 Q96B36-3;Q96B36;H9KV91 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 AATAARPPAPPPAPQPPS(0.823)PT(0.094)PS(0.027)PPRPT(0.056)LAR;AATAARPPAPPPAPQPPS(0.61)PT(0.167)PS(0.056)PPRPT(0.167)LAR;AATAARPPAPPPAPQPPS(0.678)PT(0.155)PS(0.052)PPRPT(0.115)LAR 54.263000000000005 0.00073638 89845000.0 55292.7 43737.600000000006 42886.5 65220.0 76412.0 70733.8 67966.7 61489.3 64357.3 53588.1 True False 64652.662029395244 48079.57987627154 43909.07680795698 61565.934846092925 61439.61712813166 67024.39500826166 61528.402139704434 59875.271028298695 65298.40376045025 63303.19832683377 1.0213174648079266 0.7595126493931185 0.6936312535309016 0.9725564659186512 0.9705610261731096 1.0587837072973059 0.9719635621257857 0.945849066253545 1.0315182405684347 1.0 15.94999077167852 -5.8959543454548475 8.452810017081484 0.9934245876085709 0.8187310047770241 0.46305285245750216 0.08321169154447933 0.21832400935846466 16.045597332973422 0.02359410715939555 0.035094508289181654 1.2707076793946159e-06 5.8959543454548475 -0.1746935828315468 AATAARPPAPPPAPQPPSPT(ph)PSPPRPTLAR ddPTM_PC-9_AZD4547_30min_R2 1 AATAARPPAPPPAPQPPSPTPSPPRPTLAR 30 2 Q96B36-3;Q96B36;H9KV91 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 AATAARPPAPPPAPQPPS(0.021)PT(0.788)PS(0.115)PPRPT(0.076)LAR 98.973 9.833e-13 76873000.0 13136.0 13271.0 12981.0 21553.0 18603.0 17002.0 12549.0 16428.0 12590.0 15777.0 True False 17312.974754226372 17560.59122145043 12808.863458365273 16584.28884053057 16020.294561154098 15938.86225227321 13665.836689365757 13889.430077884808 13255.481697005578 15224.65203214506 1.137167188955916 1.1534313680452801 0.8413238891319726 1.089304951306263 1.0522601454095064 1.0469114314481656 0.8976124157394173 0.9122986882431803 0.8706590908625161 1.0 13.894121634463616 -7.256391249102692 22.980309132034574 0.9128340970798671 1.049887166795259 0.3669886765105467 0.08544864337815014 154.76572232262305 704535.1764195657 0.03405851651911723 0.02548914675451128 5.5412628432965975e-08 7.256391249102692 0.13705306971539188 AATAARPPAPPPAPQPPSPT(ph)PSPPRPTLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AATAARPPAPPPAPQPPSPTPSPPRPTLAR 30 2 Q96B36-3;Q96B36;H9KV91 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 AATAARPPAPPPAPQPPS(0.231)PT(0.731)PS(0.035)PPRPT(0.003)LAR;AATAARPPAPPPAPQPPS(0.005)PT(0.949)PS(0.043)PPRPT(0.003)LAR 113.3 2.9123e-15 22834000.0 35191.9 42118.0 39704.0 40095.0 44908.0 30229.1 47553.0 27600.2 30529.6 34437.3 True False 41149.19359829192 46299.19669183506 40650.6939382585 37848.607139743865 36108.59977477539 28643.8327807108 43048.43558609384 26875.723994829186 30976.03764367125 40680.5098844832 1.0115210874971723 1.138117413555207 0.9992670704888073 0.9303867440997953 0.8876142378084677 0.7041168574840415 1.058207866822088 0.660653567793171 0.7614466419332286 1.0 15.312050141419526 -5.895359232103723 1.5401740105490482 0.8290347854464798 1.0762221175196676 0.3757741594630877 0.11921072070353898 0.3869837308884829 1.8671023827176676 0.03911307766416187 0.07535182560260652 1.2724501225849137e-06 5.895359232103723 0.24718733207318777 AATAARPPAPPPAPQPPSPT(ph)PSPPRPTLAR ddPTM_PC-9_Lapatinib_30min_R1 3 AATAARPPAPPPAPQPPSPTPSPPRPTLAR 30 2 Q96B36-3;Q96B36;H9KV91 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 AATAARPPAPPPAPQPPS(0.163)PT(0.437)PS(0.364)PPRPT(0.035)LAR;AATAARPPAPPPAPQPPS(0.111)PT(0.716)PS(0.11)PPRPT(0.064)LAR;AATAARPPAPPPAPQPPS(0.142)PT(0.836)PS(0.018)PPRPT(0.003)LAR 89.039 5.7209000000000006e-08 143637000.0 269787.0 180119.0 189278.0 188471.0 157219.0 153763.0 142378.0 137774.0 162509.0 151372.0 True False 265939.78790712316 179701.94552197814 173716.29347420926 202331.78606082563 147971.68752444675 147186.91492905992 149749.63617909575 144175.48300871497 144205.52512436477 177536.44850948825 1.497944732700397 1.0121974784934045 0.9784824183014181 1.1396633635487656 0.8334721617264894 0.8290518153583187 0.8434867174392785 0.8120894848305454 0.8122587014387519 1.0 17.43775571700185 -1.5228787452818595 0.6609792074482168 0.8605223828340648 57.50579345380096 0.7641488740122346 0.09884396237128534 112.67474351972787 0.6974579189615203 0.04190040718418006 9361.876492385065 0.029999999999894868 1.5228787452818595 56.6452710709669 AATAARPPAPPPAPQPPSPTPS(ph)PPRPTLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AATAARPPAPPPAPQPPSPTPSPPRPTLAR 30 2 Q96B36-3;Q96B36;H9KV91 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 AATAARPPAPPPAPQPPS(0.003)PT(0.215)PS(0.653)PPRPT(0.129)LAR 63.291000000000004 0.00011469 5431200.0 27507.0 27001.0 17153.0 27224.0 23916.0 23799.0 30844.0 20201.0 22914.0 19929.0 True False 32163.391811985603 29681.480836607585 17561.992573114756 25698.72754139887 19229.831482442492 22550.93854425492 27922.23302877795 19670.74515472874 23249.073900970965 23541.969942122807 1.3662149722838952 1.260790023501796 0.7459865345291988 1.0916133018850327 0.816831876419791 0.9579036333703465 1.1860618757658719 0.8355607114905272 0.9875585585287927 1.0 14.522947426638668 -5.096868689377648 6.012582760906704 0.9561205284563954 1.341725631709779 0.581169768031587 0.12381128530271718 0.13721505988724106 6.851326942856039 0.03031370176071777 0.08410120438783586 8.000761245619068e-06 5.096868689377648 0.3856051032533836 AATAARPPAPPPAPQPPSPTPSPPRPT(ph)LAR ddPTM_PC-9_Lapatinib_30min_R1 1 AATAARPPAPPPAPQPPSPTPSPPRPTLAR 30 2 Q96B36-3;Q96B36;H9KV91 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 AATAARPPAPPPAPQPPS(0.045)PT(0.137)PS(0.188)PPRPT(0.63)LAR 62.722 0.0039926 18634000.0 7389.2 10389.0 11919.0 9562.6 11250.0 11674.0 10162.0 7473.7 9943.2 8475.0 True False 7283.828652986675 10364.944908798254 10939.06582867051 10265.865503898462 10588.297118350989 11174.73023342315 10688.138636952128 7820.955386083239 8823.292109462149 9939.892457772346 0.7327874706824616 1.0427622786495587 1.100521547405362 1.0327944238341558 1.0652325629611448 1.1242304965467953 1.0752770900046007 0.7868249499991082 0.8876647455640138 1.0 13.279014527649062 -7.749928673988473 24.999860651732295 0.877933622084083 1.0340907381572746 0.21846712871729845 0.11373681061312566 278.7384041755056 605389.2266127631 0.05446253411120675 0.031092697403807972 1.7785714883385324e-08 7.749928673988473 0.1561571160731916 AATEALGEKS(ph)PDSATVSGYDIMK ddPTM_PC-9_Lapatinib_30min_R1 1 AATEALGEKSPDSATVSGYDIMK 23 1 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;H0Y2S9;K7EL39;J3QRL2;H7C3G6;Q6WCQ1;H0Y7E2 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 AAT(0.002)EALGEKS(0.981)PDS(0.008)AT(0.004)VS(0.001)GY(0.004)DIMK 64.377 0.0009167 5256200.0 33957.0 29120.0 32395.0 32223.0 32449.0 28932.0 28014.0 24378.0 30975.0 26395.0 True False 33472.76695304885 29052.574429127457 29731.608148316238 34592.78691277688 30540.41361718858 27694.645803786083 29464.42784644526 25510.690876264413 27486.26931878973 30957.340580873282 1.0812546014927942 0.9384712602566815 0.9604057580671399 1.117434064544605 0.9865322099424039 0.8946067486461344 0.9517751619998519 0.8240595089109808 0.887875663834376 1.0 14.917993920295984 -6.666927103198831 4.568706478852257 0.9031893458175039 1.0177089542453663 0.4002002687435512 0.06484356549080644 0.2190831267530049 8.007678004694329 0.022119435355952007 0.02187955378965703 2.1531431118080435e-07 6.666927103198831 0.11451960842786246 AATEALGEKSPDS(ph)ATVSGYDIMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AATEALGEKSPDSATVSGYDIMK 23 1 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;H0Y2S9;K7EL39;J3QRL2;H7C3G6;Q6WCQ1;H0Y7E2 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 AAT(0.003)EALGEKS(0.288)PDS(0.408)AT(0.136)VS(0.136)GY(0.029)DIMK;AAT(0.001)EALGEKS(0.149)PDS(0.441)AT(0.358)VS(0.033)GY(0.018)DIMK 77.575 0.00045689 21496000.0 87388.0 72965.0 69357.0 96692.0 100286.0 87280.0 98911.0 95303.0 82599.0 65295.0 True False 102181.06240832483 80208.48299111416 71010.73391788738 91274.6607196936 80635.67820907466 82702.88315234121 89541.43402637343 92801.39723187544 83806.85411304445 77132.46662506444 1.3247477603046183 1.0398796576933294 0.9206335156253413 1.183349433946841 1.0454181194676309 1.072218830422657 1.160878653882912 1.20314312885878 1.086531492898104 1.0 16.235050627235218 -7.247470979344116 23.810366172352865 1.1295669165447444 1.088546485864319 0.0 0.11068063740512672 1962.11932195103 3344610.83485309 0.042257906851643094 0.03255632822254333 5.656255523565827e-08 7.247470979344116 -0.04102043068042538 AATEALGEKSPDSATVSGY(ph)DIMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AATEALGEKSPDSATVSGYDIMK 23 1 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;H0Y2S9;K7EL39;J3QRL2;H7C3G6;Q6WCQ1;H0Y7E2 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 AATEALGEKS(0.01)PDS(0.038)AT(0.038)VS(0.233)GY(0.681)DIMK;AATEALGEKS(0.005)PDS(0.077)AT(0.077)VS(0.273)GY(0.568)DIMK 67.396 0.00093899 34661000.0 139681.0 119206.0 101576.0 160926.0 145976.0 140920.0 148834.0 153777.0 138289.0 111654.0 True False 163326.234474496 131039.9838749917 103997.95706912514 151909.83794913115 117373.05069748413 133529.90712451795 134735.36605515287 149740.51669019976 140311.21500791557 131895.98634742206 1.2382957131408439 0.9935100187948434 0.7884846229906359 1.1517396560422346 0.8898909962909437 1.0123879491889316 1.021527415551916 1.1352924439700092 1.0638020071234562 1.0 17.00904113785286 -7.54419827443317 22.135670353617055 1.075410517705227 1.0033527937233317 0.03419187222969178 0.12076614161800113 196.16919597882332 203669.52932424372 0.0560589253131941 0.03237405927723855 2.8562862260221066e-08 7.54419827443317 -0.07205772398189536 AATES(ph)VPCSPSPLAGEIR ddPTM_PC-9_AZD4547_30min_R2 1 AATESVPCSPSPLAGEIR 18 0 J3QKZ5;J3QS16;Q8N9M1-2;Q8N9M1;J9JIE4 J3QKZ5 C19orf47 Uncharacterized protein C19orf47 1 AAT(0.05)ES(0.893)VPCS(0.021)PS(0.036)PLAGEIR 179.66 1.0424999999999999e-08 5100800.0 14513.0 15710.0 20825.0 26209.0 19770.0 21591.0 19878.0 22811.0 17903.0 17989.0 True False 19127.83211084708 20787.950274205883 20548.846893186714 20166.919975013487 17025.276755040406 20240.91135683043 21647.103491211463 19286.084094632966 18849.316030301114 17359.210585425455 1.101883753107214 1.1975170283180474 1.1837431657427575 1.1617417667566834 0.9807633055235003 1.1660041369521958 1.2470096715910608 1.111000065338529 1.0858394704956646 1.0 14.0834137218948 -8.526872577159816 2.0739646646774887 1.0017613646237968 1.146778010139248 0.30870442126132036 0.06718711267502585 0.42836061114935653 4.232673410704546 0.06757860477442092 0.018806752325350746 2.972538052213923e-09 8.526872577159816 0.14501664551545113 AATESVPCS(ph)PSPLAGEIR ddPTM_PC-9_AZD4547_30min_R2 3 AATESVPCSPSPLAGEIR 18 0 J3QKZ5;J3QS16;Q8N9M1-2;Q8N9M1;J9JIE4 J3QKZ5 C19orf47 Uncharacterized protein C19orf47 1 AATES(0.029)VPCS(0.966)PS(0.005)PLAGEIR;AATESVPCS(0.863)PS(0.137)PLAGEIR;AAT(0.006)ES(0.041)VPCS(0.829)PS(0.124)PLAGEIR 155.03 1.6683e-05 19027800.0 57541.0 66404.0 87287.0 105689.0 89607.0 87940.0 78964.0 97363.0 73165.0 80151.0 True False 75837.84107284856 87867.7943990048 86129.51734768745 81324.03392877265 77166.61477940841 82441.09789818281 85991.64302646263 82317.78552916345 77032.35253069202 77344.93788606553 0.9805146030961066 1.1360510047656922 1.1135766567498213 1.0514461081935138 0.9976944437279166 1.0658887336573246 1.1117940666412365 1.0642944164028325 0.9959585544456191 1.0 16.239019252016874 -8.250990505136924 7.085648876503158 0.9976334408811565 1.0680946299052645 0.24949782689614297 0.04639364507138822 0.18405454982276787 61.19546937742452 0.03628130099802373 0.012128875761660725 5.6106024220707326e-09 8.250990505136924 0.07046118902410803 AATESVPCS(ph)PSPLAGEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AATESVPCSPSPLAGEIR 18 0 J3QKZ5;J3QS16;Q8N9M1-2;Q8N9M1;J9JIE4 J3QKZ5 C19orf47 Uncharacterized protein C19orf47 1 AAT(0.007)ES(0.026)VPCS(0.889)PS(0.078)PLAGEIR;AAT(0.018)ES(0.206)VPCS(0.606)PS(0.17)PLAGEIR 163.34 1.7291e-07 9369100.0 18333.2 20764.3 21877.5 18407.3 25467.7 24547.0 29025.0 22856.5 26152.7 18199.0 True False 21436.648662794716 22825.642477521993 22399.142570880787 17375.998658271794 20477.487006414158 23259.712107476193 26275.541877197524 22256.54109346356 26535.133761452526 21498.334636795276 0.9971306626749133 1.0617400307117266 1.0419012890674677 0.8082485900341352 0.9525150367399204 1.081930879783881 1.2222128979342364 1.0352681484160444 1.234287874375002 1.0 14.39193728567613 -6.886740368501082 4.657059912648114 1.1290026271179134 0.9725827183041856 0.3743760762505869 0.0928775259909915 0.23205918661236144 8.44485859013546 0.033974509627982805 0.029893157594417144 1.2979549872379784e-07 6.886740368501082 -0.1564199088137278 AATESVPCS(ph)PSPLAGEIR ddPTM_PC-9_Lapatinib_30min_R1 4 AATESVPCSPSPLAGEIR 18 0 J3QKZ5;J3QS16;Q8N9M1-2;Q8N9M1;J9JIE4 J3QKZ5 C19orf47 Uncharacterized protein C19orf47 1 AATES(0.005)VPCS(0.912)PS(0.083)PLAGEIR;AAT(0.002)ESVPCS(0.792)PS(0.206)PLAGEIR;AATESVPCS(0.5)PS(0.5)PLAGEIR;AAT(0.061)ES(0.01)VPCS(0.465)PS(0.465)PLAGEIR 177.67 1.6263e-08 15838000.0 28910.5 40577.2 55464.0 48593.0 53797.2 59031.0 64343.0 57649.0 66465.0 49133.0 True False 28498.23096846362 40483.24598645571 50903.964017231454 52166.69132149606 50632.95446536465 56506.381737982054 67674.36570728311 60327.58299802143 58979.01179252176 57625.573584392776 0.4945413849413212 0.7025222217904332 0.8833571772206742 0.9052697973599834 0.8786542383168227 0.9805782090000082 1.1743807739835137 1.0468890675712157 1.023486763323004 1.0 15.81442158523443 -4.52015040368041 0.5556334428119191 1.0544881351860202 2.467602769002768e-16 0.8802529153287703 0.06304795456467405 1.815626752143362 0.3460223939951078 0.03760741399649573 1.3170975188189271 3.0189060400383315e-05 4.52015040368041 -1.05448813518602 down AATESVPCS(ph)PSPLAGEIRR ddPTM_PC-9_AZD4547_30min_R2 2 AATESVPCSPSPLAGEIRR 19 1 J3QKZ5;J3QS16;Q8N9M1-2;Q8N9M1;J9JIE4 J3QKZ5 C19orf47 Uncharacterized protein C19orf47 1 AATESVPCS(0.982)PS(0.018)PLAGEIRR;AATES(0.001)VPCS(0.781)PS(0.217)PLAGEIRR 93.06200000000001 0.00038554 9697300.0 30353.0 23433.4 36056.0 77926.0 49353.0 34276.0 31171.0 43333.0 29095.0 37725.0 True False 40004.62261837951 31007.78828488707 35577.873881428095 59961.36464469845 42501.187844790555 32132.71630154788 33945.158613771644 36636.8805432787 30632.902301380273 36404.25923259633 1.0988995096090135 0.8517626491661375 0.9772997619347714 1.647097507508383 1.1674784418284507 0.8826636492242174 0.932450194821632 1.0063899476486005 0.8414647886572462 1.0 15.151819632563173 -6.75610452153533 24.965947233872157 0.9329841095009169 1.1502096717757768 0.230246838949015 0.19737900656014798 224.46325660703053 1050437.2168055214 0.07247800392825832 0.07045179331962938 1.753458446686412e-07 6.75610452153533 0.2172255622748599 AATESVPCS(ph)PSPLAGEIRR ddPTM_PC-9_Lapatinib_30min_R1 1 AATESVPCSPSPLAGEIRR 19 1 J3QKZ5;J3QS16;Q8N9M1-2;Q8N9M1;J9JIE4 J3QKZ5 C19orf47 Uncharacterized protein C19orf47 1 AATESVPCS(0.953)PS(0.047)PLAGEIRR 76.574 0.013563999999999998 0.0 5325.9 3899.5 4939.0 3278.2 4072.6 5046.2 3789.9 2783.5 3703.6 3928.8 True False 5249.951689349558 3890.470947334564 4532.934485091339 3519.28976375462 3833.0576750396654 4830.38578926674 3986.1224778768806 2912.8315716663374 3286.461567363025 4607.887845203064 1.139340163154123 0.8443067795985203 0.9837336839285806 0.7637533468654832 0.8318469988435119 1.0482863193589451 0.865064995456984 0.6321402928021944 0.7132251647106213 1.0 12.16988988704594 -7.534527835179469 23.980691438788078 0.7533300547598907 0.9237830867520993 0.1944346973983988 0.13530692888818965 197.26346843813764 406075.5043255182 0.0617745610401234 0.03570828068737568 2.9206005645379786e-08 7.534527835179469 0.17045303199220863 AATESVPCSPS(ph)PLAGEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AATESVPCSPSPLAGEIR 18 0 J3QKZ5;J3QS16;Q8N9M1-2;Q8N9M1;J9JIE4 J3QKZ5 C19orf47 Uncharacterized protein C19orf47 1 AAT(0.002)ES(0.327)VPCS(0.287)PS(0.384)PLAGEIR 94.12200000000001 0.00097749 4067900.0 9707.6 6658.9 12212.0 12542.0 15002.0 13330.0 15639.0 16330.0 15011.0 13495.0 True False 11350.9049461603 7319.951584863019 12503.180394267898 11839.312401712623 12062.465792758088 12630.951333876144 14157.56070344503 15901.35480306521 15230.507476978037 15941.536673638788 0.7120332988306178 0.4591747793653684 0.7843146272682345 0.742670712622725 0.7566689485277037 0.7923295973570047 0.888092596923622 0.9974794230069411 0.9553977002834035 1.0 13.960503083193013 -6.694685668239589 0.4907369686659834 1.021128316265839 0.5781169741249429 0.7461342493118024 0.07797468475193256 0.5340412686515713 0.271553282467 0.07002289870774704 0.10126200313851473 2.019827736848827e-07 6.694685668239589 -0.4430113421408962 AATS(ph)PAPGPSDATAR ddPTM_PC-9_AZD4547_30min_R2 2 AATSPAPGPSDATAR 15 0 Q8IXZ2-2;Q8IXZ2 Q8IXZ2-2 ZC3H3 Zinc finger CCCH domain-containing protein 3 1 AAT(0.005)S(0.993)PAPGPS(0.001)DAT(0.001)AR;AAT(0.046)S(0.833)PAPGPS(0.081)DAT(0.041)AR 116.63 0.0001412 6224000.0 30424.0 30346.0 42161.0 55797.0 41278.0 41939.0 31847.0 39607.0 32291.0 36650.0 True False 40098.19914148776 40154.75105162643 41601.91759249197 42933.86370505656 35547.26221014453 39316.547700157986 34681.32130418611 33486.64822831649 33997.83633661696 35366.89465539179 1.1337777752951423 1.1353767822390568 1.1762954592947172 1.2139562753076247 1.005099897983982 1.1116765575052843 0.980615393070673 0.9468359762598311 0.9612898352508843 1.0 15.110111930170302 -6.8721736724869675 1.1069730807039806 0.9626661605345358 1.1595028329069637 0.730015163301498 0.048204456700073485 0.25101730839170044 0.6465048534273119 0.02735344115486779 0.022174471199786553 1.3422281025821103e-07 6.8721736724869675 0.19683667237242786 AATS(ph)PAPGPSDATAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AATSPAPGPSDATAR 15 0 Q8IXZ2-2;Q8IXZ2 Q8IXZ2-2 ZC3H3 Zinc finger CCCH domain-containing protein 3 1 AAT(0.027)S(0.973)PAPGPSDATAR 87.863 0.005029100000000001 4007800.0 16900.0 13166.0 21536.0 16636.0 19506.0 17010.0 21086.0 21354.0 16070.0 11434.0 True False 19760.836209785015 14473.03346893728 22049.49991573481 15703.938854639699 15683.939324992629 16117.965655606387 19088.581430580092 20793.48012643322 16304.993348546877 13506.893688505808 1.4630185641130227 1.0715293836401218 1.6324626834442808 1.1626610245702569 1.1611803340348683 1.1933140237360842 1.4132473291637906 1.5394716658004204 1.2071608561206204 1.0 13.721408301772552 -4.465266567065694 21.444864017687696 1.2876460150704805 4.480478503980326 0.07564676690131167 0.19352731561040362 576.8860546468899 239307.36101579398 0.0454323034443648 9836.188564881824 3.425574625122244e-05 4.465266567065694 3.192832488909845 AATS(ph)PAPGPSDATAR ddPTM_PC-9_Lapatinib_30min_R1 1 AATSPAPGPSDATAR 15 0 Q8IXZ2-2;Q8IXZ2 Q8IXZ2-2 ZC3H3 Zinc finger CCCH domain-containing protein 3 1 AAT(0.054)S(0.941)PAPGPS(0.002)DAT(0.002)AR 136.33 3.0842e-05 3878200.0 15282.0 19072.0 20456.0 16259.0 20660.0 16852.0 17555.0 17361.0 19221.0 17292.0 True False 15064.075877624424 19027.839955780193 18774.186642443503 17454.74109843402 19444.819419122803 16131.279243930689 18463.912002725297 18167.655439446473 17056.12857389694 20280.899159858338 0.7427715979891321 0.938214810191537 0.9257078048887967 0.8606492720491364 0.958775016129937 0.7953927050660098 0.9104089447508632 0.8958012806160698 0.8409946935516481 1.0 14.307833995633898 -11.850029451881994 2.2580702489459212 1.6623300866566784 0.8791499479686578 0.25622903430036825 0.06376775522971151 7798149.060774343 816470.005710602 26487939.821228575 0.015489685918030332 1.4124417559811384e-12 11.850029451881994 -0.7831801386880206 AATS(ph)PGVGQSAPGTR ddPTM_PC-9_AZD4547_30min_R2 1 AATSPGVGQSAPGTR 15 0 Q6IE81-2;Q6IE81 Q6IE81-2 JADE1 Protein Jade-1 1 AAT(0.207)S(0.793)PGVGQSAPGTR 75.764 0.014637 4656300.0 12481.0 15041.0 18819.0 21341.0 15505.0 18306.0 14800.0 20563.0 14891.0 15921.0 True False 16449.69837907273 19902.709107213912 18569.447763883833 16421.162165163223 13352.398385781562 17161.32292613301 16117.17132860095 17385.460840732 15678.107859420981 15363.610635975256 1.0706922200016125 1.295444773939399 1.2086643044963548 1.0688348301870927 0.8690924745590557 1.1170110550672412 1.0490484112413763 1.1315999378441943 1.0204702677578474 1.0 13.907229686394537 -5.81432400807456 5.1404562649958345 1.0372723197141944 1.2023933126110735 0.4145078018440409 0.08469040770768142 0.18260512717916202 10.164563351328974 0.0240534827955109 0.03718378766231541 1.533472499319775e-06 5.81432400807456 0.1651209928968791 AATS(ph)PGVGQSAPGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AATSPGVGQSAPGTR 15 0 Q6IE81-2;Q6IE81 Q6IE81-2 JADE1 Protein Jade-1 1 AAT(0.06)S(0.939)PGVGQS(0.002)APGTR;AAT(0.048)S(0.952)PGVGQSAPGTR 134.37 1.1717e-05 7735200.0 30152.0 37113.0 40524.0 32643.0 37380.0 27489.0 36735.0 32593.0 29421.0 24840.0 True False 35256.138070854315 40797.33336872773 41490.24584812582 30814.118540033895 30055.657334575208 26047.42844838118 33255.19486163139 31737.468285138068 29851.226465936397 29343.295366668197 1.2015057487681724 1.3903460009836002 1.4139599976645996 1.0501246760115581 1.024276822320243 0.8876790463680886 1.1333149343344313 1.0815918215235454 1.0173099542134307 1.0 14.840743279946642 -5.774053896175942 21.40298620892317 1.0295726381522687 1.3407780008289716 0.7611319761448869 0.07892208415524624 18.055448070354466 30634.835970489716 0.022779435459090534 0.03416874896766796 1.6824652532823424e-06 5.774053896175942 0.31120536267670285 AATS(ph)PGVGQSAPGTR ddPTM_PC-9_Lapatinib_30min_R1 1 AATSPGVGQSAPGTR 15 0 Q6IE81-2;Q6IE81 Q6IE81-2 JADE1 Protein Jade-1 1 AAT(0.156)S(0.844)PGVGQSAPGTR 138.28 4.9901e-05 3825300.0 14496.0 20515.0 19982.0 18355.0 20523.0 18089.0 20859.0 15602.0 18057.0 16867.0 True False 14289.28438175917 20467.49877793784 18339.157092750578 19704.887930485052 19315.877489770442 17315.375637518548 21938.976956129147 16326.925877901269 16023.230511360332 19782.438476135238 0.7223216894619541 1.0346297198208922 0.9270422913168274 0.996079828796448 0.976415395557649 0.8752902559715852 1.1090127732531798 0.8253242337944049 0.809972467787029 1.0 14.27193264996384 -10.47569832597172 14.976027256866242 0.999999999999999 0.9285900136997565 0.04044225496233056 0.10989211001291865 0.0 0.0 0.10290746317233446 0.02495872590140556 3.3442726261208884e-11 10.47569832597172 -0.07140998630024253 AATSEEPTGFSVDSNLLGSLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 AATSEEPTGFSVDSNLLGSLSPK 23 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 AATSEEPTGFSVDSNLLGS(0.081)LS(0.919)PK;AATSEEPTGFSVDS(0.002)NLLGS(0.069)LS(0.929)PK 94.01899999999999 0.00015484 0.0 19569.199999999997 15269.900000000001 15193.0 11925.599999999999 14915.9 15673.1 15428.9 14970.5 15912.2 13295.6 True False 19290.13961944824 15234.543484729858 13943.89018667599 12802.648406635386 14038.576087787691 15002.798048780582 16227.732947812492 15666.084082497176 14120.000473105612 15593.726744726597 1.2370448665179847 0.9769661694169288 0.8941987002171536 0.8210127454596392 0.9002707510271836 0.9621047164914666 1.0406577730560977 1.0046401568371108 0.9054923626823613 1.0 13.928678138477576 -4.7674120393173895 4.037887170912779 0.9394567980435172 1.2673881608066035 0.6749762248245783 0.06121783478465008 0.15618474005332772 4.845283033873467 0.01738928709351871 0.15310463092001952 1.7083936978820333e-05 4.7674120393173895 0.3279313627630863 AATSGVPSIYAPSTYAHLS(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 2 AATSGVPSIYAPSTYAHLSPAK 22 0 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 1 AATSGVPSIYAPS(0.001)T(0.002)YAHLS(0.998)PAK;AATSGVPSIYAPS(0.157)T(0.332)Y(0.124)AHLS(0.387)PAK 158.83 2.2727000000000003e-06 24570000.0 98271.0 155688.0 230691.0 218268.0 200406.0 182788.0 201077.0 257536.0 209735.0 168328.0 True False 129519.13383621968 206011.1013552237 227631.88660917824 167949.68480698424 172583.0861593637 171358.2374643288 218972.46346223645 217739.7287885405 220821.1639175111 162434.88795505557 0.7973603175203137 1.2682688057274083 1.4013731254098698 1.0339508151318735 1.0624754837588588 1.0549349319078685 1.348063006777364 1.3404739063740256 1.359444185282478 1.0 17.30950200396792 -7.26276230931027 24.987526959320604 1.2903681020259874 1.1191435751306185 0.15062497952661913 0.1774690375740629 221.12130490695225 4176476.227750514 0.0722095100129702 0.051662752737384764 5.46056637780395e-08 7.26276230931027 -0.17122452689536893 AATSGVPSIYAPSTYAHLS(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AATSGVPSIYAPSTYAHLSPAK 22 0 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 1 AATSGVPSIYAPS(0.215)T(0.215)Y(0.175)AHLS(0.394)PAK 82.302 0.00020338 8364400.0 26850.0 29554.0 35676.0 33973.0 69474.0 31971.0 41053.0 44540.0 34584.0 40376.0 True False 31395.174688327097 32487.92580441838 36526.65114198342 32069.602951952078 55861.06842328195 30294.384478271124 37164.1626420186 43370.87219403092 35089.725573500036 47695.84918375984 0.6582370421243484 0.6811478642355387 0.7658245270202786 0.672377229900995 1.1711934975319052 0.6351576708814776 0.7791907111001345 0.9093217321057457 0.7356976796515007 1.0 15.541576098137224 -1.9635174496140162 0.15478895754809 0.9537020733943344 5.491938028022014e-60 0.21091232417349137 0.14681206295424457 102.26945475637469 1.1677124100121503 0.49287696078558574 21.48850104637528 0.01087633436488733 1.9635174496140162 -0.9537020733943344 AATTATPAATT(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 1 AATTATPAATTSPK 14 0 Q92766;Q92766-2;Q92766-5;Q92766-3;A0A087X055 Q92766 RREB1 Ras-responsive element-binding protein 1 1 AATTATPAAT(0.001)T(0.5)S(0.5)PK 260.97 5.3676999999999993e-45 13109000.0 62038.0 82213.0 55929.0 57377.0 56536.0 65612.0 75479.0 67745.0 58566.0 54391.0 True False 61153.32674362412 82022.64084965184 51330.733512183346 61596.69598406106 53210.663634052624 62805.92770904227 79386.93329841668 70892.68001528161 51969.68035267929 63792.41187854814 0.9586301088607769 1.2857742548723745 0.8046526538283253 0.9655802966241906 0.8341221481852467 0.9845360264574413 1.2444573102136087 1.1113027071346886 0.8146686858559653 1.0 15.96109720485218 -7.030630644534548 24.5654170933197 1.0608272862644712 0.9710471293475819 0.041785424697086126 0.1569186328218735 1736.404321783243 1392570.4001480902 0.06138175759382266 0.0476143578096818 9.319000938390524e-08 7.030630644534548 -0.08978015691688934 AATTATPAATTS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 AATTATPAATTSPK 14 0 Q92766;Q92766-2;Q92766-5;Q92766-3;A0A087X055 Q92766 RREB1 Ras-responsive element-binding protein 1 1 AATTATPAATT(0.019)S(0.981)PK;AATTATPAATT(0.02)S(0.98)PK;AATTATPAAT(0.206)T(0.206)S(0.588)PK;AATTATPAATT(0.023)S(0.977)PK 238.03 4.8578999999999995e-27 60795900.0 203154.0 218098.0 172690.0 176535.0 180182.0 197901.0 208676.0 212985.0 190309.0 194551.0 True False 267752.7461342952 288593.9133611554 170400.0177663585 135837.5831885616 155166.83946771294 185526.2191852205 227247.7597410227 180073.06215840593 200368.345216476 187739.8287067155 1.4261904252217825 1.5372013245627958 0.9076391458338604 0.723541638044025 0.8264993131005376 0.988209164050357 1.2104397948291832 0.9591628127013663 1.067266048961239 1.0 17.5183752225392 -5.261939257851785 24.998078621173093 0.9555759362531042 1.4816959134062777 0.7316475444530613 0.1262703155860254 23.009994419291825 1150760.360228003 0.03688543850951376 0.08505825346338265 5.470924760660511e-06 5.261939257851785 0.5261199771531735 AATTATPAATTS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AATTATPAATTSPK 14 0 Q92766;Q92766-2;Q92766-5;Q92766-3;A0A087X055 Q92766 RREB1 Ras-responsive element-binding protein 1 1 AATTATPAATT(0.076)S(0.924)PK;AATTATPAAT(0.001)T(0.135)S(0.865)PK;AATTATPAATT(0.046)S(0.954)PK;AATTATPAAT(0.001)T(0.226)S(0.773)PK 236.05 6.916e-27 56289600.0 198152.0 242024.0 155382.0 205142.0 216108.0 160768.0 237469.0 167282.0 152424.0 162899.0 True False 231695.21991960448 266050.5432391063 159086.89616951635 193648.55881933725 173763.18874425816 152337.04306411106 214974.21719332313 162891.0247499295 154652.91264212225 192431.2991922251 1.2040412390925945 1.382574167278998 0.8267204806978927 1.0063256841907833 0.902988180580131 0.7916437902959708 1.1171478761289206 0.8464892428295306 0.8036785766728887 1.0 17.553983948788705 -5.261758885487821 24.999961653504126 0.9124848622752627 1.293307722433578 0.6741191585730233 0.10608086576282544 14.749521252530972 1154204.0780436269 0.02661976346234639 0.06161242393884301 5.473197431906939e-06 5.261758885487821 0.38082286015831535 AATTATPAATTS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 AATTATPAATTSPK 14 0 Q92766;Q92766-2;Q92766-5;Q92766-3;A0A087X055 Q92766 RREB1 Ras-responsive element-binding protein 1 1 AATTATPAAT(0.003)T(0.133)S(0.863)PK;AATTATPAAT(0.001)T(0.087)S(0.912)PK;AATTATPAATT(0.078)S(0.921)PK 215.96 2.1804e-15 75049000.0 223326.0 258745.0 184380.0 174005.0 178501.0 211877.0 227799.0 216107.0 179603.0 158693.0 True False 220141.33028702746 258145.89184974527 169220.98812738195 186801.9081636637 168001.92212646845 202815.51461941062 239593.31759093268 226148.12015739037 159374.21883656486 186122.8736048691 1.182774185801462 1.3869648950175677 0.909189638274288 1.0036483133192762 0.9026398468526192 1.0896861341716617 1.2872857212573403 1.215047434940711 0.8562849678267354 1.0 17.5058958410025 -5.256343402564673 24.99685261491367 1.0460590576590179 1.284869541971206 0.3466857153536541 0.13738059325621213 516.1820167988284 2531962.351263153 0.037576388260722016 0.09309122635342616 5.5418733618725495e-06 5.256343402564673 0.2388104843121881 AAVAGEDGR ddPTM_PC-9_AZD4547_30min_R2 1 AAVAGEDGR 9 0 B4DY08;B2R5W2;G3V4W0;G3V576;G3V555;G3V575;G3V5X6;G3V3K6;G3V251;B4DSU6;B7ZW38;P0DMR1;A0A0G2JPF8;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;A0A0G2JNQ3;B2RXH8;O60812 B4DY08;P07910-2;A0A0G2JNQ3 HNRNPC;HNRNPCL3;HNRNPCL4;HNRNPCL2;HNRNPCL1 Heterogeneous nuclear ribonucleoprotein C-like 3;Heterogeneous nuclear ribonucleoprotein C-like 4;Heterogeneous nuclear ribonucleoproteins C1/C2;Heterogeneous nuclear ribonucleoprotein C-like 2;Heterogeneous nuclear ribonucleoprotein C-like 1 0 103.56 0.012972999999999998 13969000.0 48267.0 32410.0 41272.0 71801.0 57253.0 59128.0 53652.0 46830.0 47358.0 58617.0 False True 63614.901984031996 42885.898687906585 40724.70631335426 55248.388764391726 49304.409208716665 55430.71681286972 58426.92406230391 39593.499546344385 49861.24719672682 56564.83667162621 1.1246368897577355 0.7581724126045043 0.7199650650415896 0.9767267443044729 0.8716441540341 0.9799500904538918 1.0329195220961673 0.6999666555424723 0.8814883968672005 1.0 15.787617865040378 -4.743399852242116 24.935545024342122 0.8763647380848066 1.1246376935709888 0.292005251932005 0.11410199919307067 1551.5033932395754 2144484.3974067573 0.02918811594609702 0.9343281450492754 1.80551103769077e-05 4.743399852242116 0.2482729554861821 AAVAGEDGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AAVAGEDGR 9 0 B4DY08;B2R5W2;G3V4W0;G3V576;G3V555;G3V575;G3V5X6;G3V3K6;G3V251;B4DSU6;B7ZW38;P0DMR1;A0A0G2JPF8;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;A0A0G2JNQ3;B2RXH8;O60812 B4DY08;P07910-2;A0A0G2JNQ3 HNRNPC;HNRNPCL3;HNRNPCL4;HNRNPCL2;HNRNPCL1 Heterogeneous nuclear ribonucleoprotein C-like 3;Heterogeneous nuclear ribonucleoprotein C-like 4;Heterogeneous nuclear ribonucleoproteins C1/C2;Heterogeneous nuclear ribonucleoprotein C-like 2;Heterogeneous nuclear ribonucleoprotein C-like 1 0 ;; 107.66 0.01146 19176000.0 85684.0 84432.0 113050.0 102020.0 128030.0 110009.0 77641.0 91784.0 99395.0 97624.0 False True 100188.6088638594 92813.85096835122 115745.5407445126 96304.15015330257 102943.44057104494 104239.93438022368 70286.28240783786 89374.76725318657 100848.46383813415 115322.45840884095 0.8687692774348509 0.8048202600685788 1.003668689876275 0.8350858235425861 0.8926573539222521 0.9038996897783126 0.6094761018591806 0.7749988032368798 0.8744911028570548 1.0 16.815313971641018 AAVAGEDGR ddPTM_PC-9_Lapatinib_30min_R1 2 AAVAGEDGR 9 0 B4DY08;B2R5W2;G3V4W0;G3V576;G3V555;G3V575;G3V5X6;G3V3K6;G3V251;B4DSU6;B7ZW38;P0DMR1;A0A0G2JPF8;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;A0A0G2JNQ3;B2RXH8;O60812 B4DY08;P07910-2;A0A0G2JNQ3 HNRNPC;HNRNPCL3;HNRNPCL4;HNRNPCL2;HNRNPCL1 Heterogeneous nuclear ribonucleoprotein C-like 3;Heterogeneous nuclear ribonucleoprotein C-like 4;Heterogeneous nuclear ribonucleoproteins C1/C2;Heterogeneous nuclear ribonucleoprotein C-like 2;Heterogeneous nuclear ribonucleoprotein C-like 1 0 ; 94.302 0.026681 27711100.0 61484.0 65599.0 61344.0 58886.0 69606.0 57863.0 64255.0 61144.0 82305.0 56492.0 False True 60607.226885215285 65447.109545890606 56300.53311468784 63216.672877937446 65511.91193066129 55388.334375241044 67581.80949787042 63984.97345714624 73034.94418992694 66256.56692914154 0.9147353944557982 0.9877829863398052 0.849735139082874 0.9541193546225368 0.9887610385959685 0.8359674662056731 1.0200016787791943 0.9657151950775736 1.102304987640464 1.0 16.015775831947906 -7.640946207511992 2.072700996341457 1.0358443851290424 0.9270203299046217 0.3799047331665031 0.059280706311878026 0.3438508695438346 2.93491246185176 0.03614684059139202 0.016794385649501937 2.2858819192471288e-08 7.640946207511992 -0.10882405522442073 AAVDCS(ph)VPVS(ph)VS(ph)T(ph)SIK ddPTM_PC-9_AZD4547_30min_R2 1 AAVDCSVPVSVSTSIK 16 0 G3V2V4;G3V287;G3V5N2;Q9P0W8-3;Q9P0W8 G3V2V4 SPATA7 Spermatogenesis-associated protein 7 4 AAVDCS(0.999)VPVS(0.998)VS(0.998)T(0.994)S(0.011)IK 53.013000000000005 0.045727 0.0 8491.2 6823.9 9565.0 13071.0 11152.0 9274.0 9342.3 13682.0 9540.6 11413.0 True False 11191.224972068127 9029.592226362412 9438.161850340028 10057.682894936905 9603.737297532145 8694.095313938462 10173.746601566801 11567.761281082292 10044.896638479071 11013.434343846844 1.0161430687894928 0.8198707092131715 0.8569680951167685 0.9132194900272944 0.8720020474719323 0.7894081938932894 0.9237578655245562 1.050331887395792 0.9120585209727163 1.0 13.426976797428749 -7.526887634740523 24.65539791674777 0.9861261342378919 0.8740858827331462 0.3638549589864536 0.06474528137598612 102.61258473906639 631065.9412646441 0.029098295701628085 0.016898213602741956 2.9724349920610372e-08 7.526887634740523 -0.11204025150474561 AAVEEGIVLGGGCALLR ddPTM_PC-9_Lapatinib_30min_R1 4 AAVEEGIVLGGGCALLR 17 0 P10809 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 ;;; 218.94 6.2751000000000005e-22 10666780.0 33631.7 31986.22 31704.129999999997 28970.6 27813.47 24061.5 35015.700000000004 26171.18 34086.6 28706.5 False True 33152.105790701586 31912.15787281752 29097.538812880935 31101.194567088543 26177.536377985947 23032.44573509603 36828.64161286407 27387.188565389835 30247.408160189134 33668.38027599313 0.9846658947932917 0.9478376331507737 0.864239341909436 0.923750840169312 0.777511010728709 0.6840972314762366 1.093864370990378 0.8134394449892195 0.898392138624997 1.0 15.039106696972798 -10.605971574358225 21.222510080319708 0.9999999997418828 0.884356864104062 0.08824061101263447 0.10802218812646897 0.0 0.0 0.10498491606964687 0.025462582238338766 2.4775842163057456e-11 10.605971574358225 -0.1156431356378208 AAVGEEKDINTFVGT(ph)PVEK ddPTM_PC-9_AZD4547_30min_R2 1 AAVGEEKDINTFVGTPVEK 19 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 AAVGEEKDINT(0.01)FVGT(0.99)PVEK 59.996 0.014929 7799000.0 23777.0 27861.0 39057.0 46360.0 35423.0 36467.0 30659.0 35615.0 32191.0 34354.0 True False 31337.59140767663 36866.52339845001 38539.078660609564 35672.41825485998 30505.127895487905 34186.71272518804 33387.59160564708 30111.52010128238 33892.55054077099 33151.276916543786 0.9452906289723623 1.1120694835151936 1.162521695849883 1.0760495996779553 0.9201795747500952 1.0312336629219712 1.0071283736580707 0.9083064938067454 1.0223603339953786 1.0 15.016776820496244 -6.167960962515054 7.9528525817282105 0.9808278704502081 1.0837222577859622 0.33251927996703634 0.06361405571182618 0.33547247035502614 25.629575211740732 0.018920449772628172 0.024478990327053925 6.792646870269819e-07 6.167960962515054 0.10289438733575407 AAVGEEKDINTFVGT(ph)PVEK ddPTM_PC-9_Lapatinib_30min_R1 1 AAVGEEKDINTFVGTPVEK 19 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 AAVGEEKDINT(0.023)FVGT(0.977)PVEK 51.495 0.037357 9141800.0 31140.0 25862.0 37555.0 27832.0 23047.0 26989.0 21031.0 20275.0 25681.0 16026.0 True False 30695.937889623394 25802.118127956557 34467.372866492275 29878.85812483028 21691.42077214538 25834.74338443185 22119.88227452668 21217.0505175265 22788.535347081168 18796.0727466973 1.6331038032940708 1.37273985239764 1.8337539618508134 1.5896330327876795 1.1540400521144412 1.3744756009720878 1.1768353194107217 1.1288023196896062 1.2124094035061337 1.0 14.19814363609426 -6.256486260980335 22.902104562690106 1.190990057149644 1.6067276428832318 0.7096656948229434 0.13539389859678838 74.7506317095079 345627.8121505872 0.04018933884779665 0.05012475997753763 5.540050697568366e-07 6.256486260980335 0.4157375857335879 AAVGQES(ph)PGGLEAGNAK ddPTM_PC-9_AZD4547_30min_R2 4 AAVGQESPGGLEAGNAK 17 0 Q29RF7 Q29RF7 PDS5A Sister chromatid cohesion protein PDS5 homolog A 1 AAVGQES(1)PGGLEAGNAK;AAVGQES(1)PGGLEAGNAK;AAVGQES(1)PGGLEAGNAK;AAVGQES(1)PGGLEAGNAK 250.38 9.0579e-48 288809000.0 736672.0 712663.0 995813.0 1203257.0 1013041.0 1014359.0 861835.0 1109988.0 800946.0 988408.0 True False 970918.3722705106 943017.3778654615 982607.8689673435 925864.6887853327 872397.7435105166 950930.9713771103 938536.6454043792 938464.8595867561 843282.3703963332 953804.1367679825 1.0179431340699787 0.9886908029786152 1.0301987914384225 0.9707073528981284 0.9146508280690457 0.9969876777840281 0.9839930539457105 0.9839177913054514 0.8841253019239795 1.0 19.863333514331707 -5.885709572374669 6.38809234163591 0.9610891200167808 1.0095785807010829 0.2934546911509187 0.03588027534381604 0.2818918487506596 14.690608065720046 0.010053964448094612 0.015054108471356072 1.3010393368391954e-06 5.885709572374669 0.048489460684302044 AAVGQES(ph)PGGLEAGNAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 AAVGQESPGGLEAGNAK 17 0 Q29RF7 Q29RF7 PDS5A Sister chromatid cohesion protein PDS5 homolog A 1 AAVGQES(1)PGGLEAGNAK;AAVGQES(1)PGGLEAGNAK;AAVGQES(1)PGGLEAGNAK;AAVGQES(1)PGGLEAGNAK;AAVGQES(1)PGGLEAGNAK 213.64 3.2114e-22 241327000.0 814210.4 700458.8 696724.1 863924.0 918553.0 795914.4 834373.5 776818.4 697338.5 621022.9 True False 952040.1393315713 769995.7204930605 713336.6448848643 815521.1391593993 738569.1335378818 754175.247736777 755335.6017389798 756427.7401071311 707535.7563276686 733609.4357554279 1.297747947245548 1.0495989868235054 0.9723656895856474 1.1116557386146806 1.0067606788308914 1.0280337342719312 1.0296154396667208 1.0311041587520016 0.9644583641417995 1.0 19.484652669572093 -4.765498941244563 4.475307409894272 1.0220862709314937 1.3202035946871062 0.8248994090860263 0.03838407534653971 0.0761869026319325 3.3450361360077796 0.009208307280697572 0.07316270030916033 1.7159358933522294e-05 4.765498941244563 0.2981173237556125 AAVGQES(ph)PGGLEAGNAK ddPTM_PC-9_Lapatinib_30min_R1 4 AAVGQESPGGLEAGNAK 17 0 Q29RF7 Q29RF7 PDS5A Sister chromatid cohesion protein PDS5 homolog A 1 AAVGQES(1)PGGLEAGNAK;AAVGQES(1)PGGLEAGNAK;AAVGQES(1)PGGLEAGNAK;AAVGQES(1)PGGLEAGNAK 245.67 2.8215999999999997e-47 334140000.0 1307209.0 1081887.0 1223143.0 1035106.0 989796.0 1010225.0 949070.0 961800.0 1104732.0 713762.0 True False 1288567.95994723 1079381.957122439 1122580.9040085205 1111231.1482523908 931578.1452938076 967020.0316994942 998208.2007648244 1006488.7392235264 980305.4488163099 837134.8106719173 1.539259798446292 1.289376505865387 1.3409798394448476 1.3274219804101481 1.1128173544068565 1.155154485719362 1.1924103358736489 1.2023018591422319 1.1710245904473597 1.0 19.675100444914676 -1.5228787452803376 0.26091814819697845 1.0888548825496709 3.7811368611222647 0.766037312636734 0.06819476388234169 26.312192053224745 0.36351877000350497 0.08528051758531068 31.53467964060084 0.029999999999999995 1.5228787452803376 2.692281978572594 AAVHLEGK ddPTM_PC-9_Lapatinib_30min_R1 1 AAVHLEGK 8 0 P18206;P18206-2 P18206 VCL Vinculin 0 81.548 0.01617 0.0 76593.0 95833.0 105160.0 90403.0 100850.0 97909.0 87367.0 86448.0 97987.0 86170.0 False True 75500.76977456416 95611.10457646208 96514.15072933894 97051.53819556745 94918.20127872868 93721.66030702661 91890.43576998576 90464.68967393987 86950.6722111461 101064.36968569217 0.7470562574067379 0.9460416650676235 0.9549770213725737 0.9602943005274308 0.9391856059056428 0.9273462111177142 0.9092268230214354 0.8951195159607974 0.8603494236550493 1.0 16.624914938167414 -4.758409430088992 24.999883675346133 0.9301178568357014 0.7470560083502089 0.69934420846631 0.03644796600228507 49.588984092688776 409083.31113837793 0.009390326025091236 0.06446148828364859 1.744177058817821e-05 4.758409430088992 -0.18306184848549245 AAVPS(ph)GASTGIYEALELR ddPTM_PC-9_AZD4547_30min_R2 1 AAVPSGASTGIYEALELR 18 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798;P13929-3;P09104-2;F5H1C3;P13929-2;E5RI09;E5RG95;K7EKN2;P09104;K7EPM1;E5RGZ4;F5H0C8;P13929 P06733 ENO1;ENO3;ENO2 Alpha-enolase;Enolase;Beta-enolase;Gamma-enolase 1 AAVPS(0.837)GAS(0.072)T(0.092)GIYEALELR 108.18 0.00027816 2603000.0 3520.0 3178.0 4920.7 7504.0 5360.6 4915.3 3337.0 4630.1 4106.9 4404.1 True False 4639.286779451647 4205.226350822807 4855.448302871738 5774.0687356442895 4616.373220691432 4607.945513974741 3633.986535374416 3914.6244341133693 4323.982349597477 4249.913799503712 1.091619030012657 0.989485092924444 1.1424815965534967 1.3586319647985714 1.086227495068374 1.0842444650319352 0.855072998374409 0.9211067844647822 1.0174282476276142 1.0 12.053217864197201 -7.072841136552131 4.377485509204928 0.9422701805320838 1.1351105055659645 0.45200610282685527 0.09641732667419714 0.22257687466450948 8.055496254036122 0.04086267875372598 0.03187972725948373 8.455881018527973e-08 7.072841136552131 0.1928403250338807 AAVPS(ph)GASTGIYEALELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAVPSGASTGIYEALELR 18 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798;P13929-3;P09104-2;F5H1C3;P13929-2;E5RI09;E5RG95;K7EKN2;P09104;K7EPM1;E5RGZ4;F5H0C8;P13929 P06733 ENO1;ENO3;ENO2 Alpha-enolase;Enolase;Beta-enolase;Gamma-enolase 1 AAVPS(0.714)GAS(0.264)T(0.022)GIYEALELR 105.0 0.00035273 2165200.0 1457.4 1722.2 2629.5 3718.1 5614.4 3969.3 3732.3 1022.9 997.32 3804.5 True False 1704.1090350379104 1893.1686343767121 2692.197252434283 3509.7869112428416 4514.298623307625 3761.1429204467017 3378.749524488005 996.0499588521371 1011.9039182559283 4494.225733594573 0.3791774459167918 0.4212446696268897 0.5990347196648285 0.7809547448867555 1.0044663732760475 0.8368834018131224 0.7517979124260882 0.22162882282627938 0.22515645146435198 1.0 12.133856873923712 -5.321631393576207 3.20621808237915 0.6785994532291902 0.3904769867695847 0.16215292509550905 0.2580914798863246 0.5230048463628691 10.56417493022108 0.07779697349629085 0.20143928587575344 4.768355281414723e-06 5.321631393576207 -0.28812246645960554 AAVPS(ph)IK ddPTM_PC-9_Lapatinib_30min_R1 2 AAVPSIK 7 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 1 AAVPS(1)IK;AAVPS(1)IK 102.62 0.010818000000000001 9362200.0 85465.0 121797.0 102369.0 98823.0 149956.0 113122.0 125978.0 137240.0 94291.0 100528.0 True False 84246.25342763866 121514.98652968537 93952.61597576732 106090.77308386404 141135.88290483924 108284.03576026154 132500.52442491197 143616.6714192522 83670.95465175151 117904.13085486012 0.7145318218862553 1.0306253534006387 0.7968560159391099 0.8998053954060498 1.1970393393474685 0.9184074805110864 1.123798831001265 1.2180800653714516 0.709652444279076 1.0 16.8472547394841 -6.0241587375160135 23.80475928830796 1.0390030131093462 0.8627771727519681 0.2180482239456495 0.15596987247829397 605.4114586992508 596541.0341817576 0.04382429460951847 0.05694635927247608 9.458913686007491e-07 6.0241587375160135 -0.1762258403573781 AAVPSGAS(ph)TGIYEALELR ddPTM_PC-9_AZD4547_30min_R2 4 AAVPSGASTGIYEALELR 18 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798;P13929-3;P09104-2;F5H1C3;P13929-2;E5RI09;E5RG95;K7EKN2;P09104;K7EPM1;E5RGZ4;F5H0C8;P13929 P06733 ENO1;ENO3;ENO2 Alpha-enolase;Enolase;Beta-enolase;Gamma-enolase 1 AAVPSGAS(0.976)T(0.024)GIYEALELR;AAVPS(0.244)GAS(0.718)T(0.038)GIY(0.001)EALELR;AAVPS(0.045)GAS(0.771)T(0.184)GIYEALELR;AAVPS(0.071)GAS(0.702)T(0.221)GIY(0.006)EALELR 167.35 1.1474000000000001e-07 5222200.0 15557.9 13638.84 22629.100000000002 37134.5 29565.000000000004 20334.899999999998 15764.0 27826.799999999996 19402.300000000003 19943.5 True False 20504.988575576914 18047.328307947177 22329.02334840873 28573.71474730584 25460.410079047506 19063.355488398458 17166.965461085496 23526.80745625059 20427.86596741949 19245.28413532895 1.0654552269215656 0.9377532792471137 1.1602334988351197 1.484712542895249 1.3229427999095802 0.9905468453647549 0.892008937897246 1.2224712969065477 1.061447875945861 1.0 14.232217350651643 -6.7814221096059875 24.99591519823655 1.0383690489887123 1.19422178153732 0.2093161570279164 0.15622831652989538 478.2433394621283 598219.1161312922 0.06248848782051992 0.05518039527576602 1.6541614307976773e-07 6.7814221096059875 0.15585273254860765 AAVPSGAS(ph)TGIYEALELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AAVPSGASTGIYEALELR 18 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798;P13929-3;P09104-2;F5H1C3;P13929-2;E5RI09;E5RG95;K7EKN2;P09104;K7EPM1;E5RGZ4;F5H0C8;P13929 P06733 ENO1;ENO3;ENO2 Alpha-enolase;Enolase;Beta-enolase;Gamma-enolase 1 AAVPS(0.074)GAS(0.852)T(0.074)GIYEALELR;AAVPS(0.023)GAS(0.746)T(0.231)GIYEALELR;AAVPS(0.102)GAS(0.742)T(0.156)GIYEALELR 100.27 0.0005981 3552800.0 18491.2 16097.9 17513.0 20016.5 25211.2 21160.800000000003 18865.0 21949.0 16979.4 14215.36 True False 21621.394942152478 17695.99312468521 17930.576338422346 18895.040399368587 20271.246340113503 20051.0903965406 17077.970629227595 21372.86200688783 17227.6916031311 16792.492239272156 1.2875631939603995 1.0538038590424392 1.0677733884246545 1.1252076302991676 1.2071612748884097 1.1940508955334006 1.0170003586059606 1.2727629527738404 1.0259163057905816 1.0 14.035528741713094 -8.495081201232809 23.8234802830254 0.9999999442109679 1.1449890018460325 0.29700771849593643 0.08600896489504632 406.5257238144494 348407.0847934151 0.07981954845565252 0.020609318775681146 3.198297059392836e-09 8.495081201232809 0.14498905763506453 AAVPSGAS(ph)TGIYEALELR ddPTM_PC-9_Lapatinib_30min_R1 2 AAVPSGASTGIYEALELR 18 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798;P13929-3;P09104-2;F5H1C3;P13929-2;E5RI09;E5RG95;K7EKN2;P09104;K7EPM1;E5RGZ4;F5H0C8;P13929 P06733 ENO1;ENO3;ENO2 Alpha-enolase;Enolase;Beta-enolase;Gamma-enolase 1 AAVPS(0.016)GAS(0.936)T(0.048)GIYEALELR;AAVPS(0.002)GAS(0.573)T(0.425)GIYEALELR 110.26 0.0013452 2317300.0 12576.1 14155.6 20939.6 14486.5 15908.2 14659.3 14982.6 14638.2 14820.5 11854.900000000001 True False 12396.762507825713 14122.823577917481 19218.026917193474 15551.885535547348 14972.510952724559 14032.35591149735 15758.325717575175 15318.344211376394 13151.25922321625 13904.003669338683 0.8915966079010206 1.015737906417656 1.3821937460771356 1.1185185149111114 1.0768488925058446 1.0092313153255068 1.1333660499763583 1.101721818813716 0.9458613170692413 1.0 13.763212747549154 -6.452419937168379 4.497721801148846 1.0496225096534366 1.1149675892939637 0.04760995595255657 0.12482454412492562 0.8169612256839875 31.52893648801954 0.042599092584454414 0.0475840103777233 3.528418275375221e-07 6.452419937168379 0.06534507964052705 AAVPSGASTGIYEALELR ddPTM_PC-9_AZD4547_30min_R2 1 AAVPSGASTGIYEALELR 18 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798;P13929-3;P09104-2;F5H1C3;P13929-2;E5RI09;E5RG95;K7EKN2;P09104;K7EPM1;E5RGZ4;F5H0C8;P13929 P06733 ENO1;ENO3;ENO2 Alpha-enolase;Enolase;Beta-enolase;Gamma-enolase 0 225.86 2.967e-34 9305100.0 6510.1 5431.7 9806.6 9799.9 9373.6 9742.0 6654.1 10010.0 9932.3 10500.0 False True 8580.176381508003 7187.390802317256 9676.558076481386 7540.684461945699 8072.2374401136385 9132.831199955637 7246.302009300246 8463.184506916661 10457.301100807663 10132.39819595126 0.846806078440196 0.709347447990074 0.9550116260085376 0.7442151715828571 0.7966758988350036 0.9013494163311669 0.7151615904905662 0.8352597621260494 1.0320657457961164 1.0 13.306688059702612 -8.2227427729151 5.393959825784869 1.0171876974545844 0.8101208929467318 0.5452036480519568 0.0743077838304088 0.12628795729371742 9.812644077060593 0.052269533471427564 0.017977476472174705 5.987661316024208e-09 8.2227427729151 -0.20706680450785253 AAVPSGASTGIYEALELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAVPSGASTGIYEALELR 18 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798;P13929-3;P09104-2;F5H1C3;P13929-2;E5RI09;E5RG95;K7EKN2;P09104;K7EPM1;E5RGZ4;F5H0C8;P13929 P06733 ENO1;ENO3;ENO2 Alpha-enolase;Enolase;Beta-enolase;Gamma-enolase 0 156.6 6.2444e-05 7791600.0 7678.0 3902.6 5146.3 8085.1 6301.3 6233.0 5753.7 4018.9 5050.9 4694.9 False True 8977.733752587537 4290.024336615117 5269.007309451432 7632.118059247865 5066.605499260533 5906.1305074306065 5208.667882819342 3913.4081333765344 5124.759857135992 5546.04820519205 1.6187623007284435 0.7735281371335576 0.9500471533079607 1.376136264395051 0.913552373114486 1.0649259236335988 0.9391674378061008 0.7056210095168151 0.9240381020017714 1.0 12.437244440723806 -6.994270113407995 1.3585402624067426 0.8626901074339244 1.12471800393617 0.19123011241772936 0.23432059735788463 0.7578804341037831 2.8521516619104013 0.12288681479347405 0.09030500990223551 1.0132809703835736e-07 6.994270113407995 0.26202789650224556 AAVPSGASTGIYEALELR ddPTM_PC-9_Lapatinib_30min_R1 3 AAVPSGASTGIYEALELR 18 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798;P13929-3;P09104-2;F5H1C3;P13929-2;E5RI09;E5RG95;K7EKN2;P09104;K7EPM1;E5RGZ4;F5H0C8;P13929 P06733 ENO1;ENO3;ENO2 Alpha-enolase;Enolase;Beta-enolase;Gamma-enolase 0 ;; 288.29 2.6846999999999994e-105 61318800.0 16706.1 23000.5 21437.859999999997 13572.6 18645.9 22455.100000000002 22005.600000000002 17950.4 27708.9 25074.399999999998 False True 16467.867950476466 22947.243755396503 19675.321903332708 14570.774280866319 17549.18482124985 21494.747718394756 23144.942293772274 18784.441115156962 24588.031894347467 29408.47663046216 0.5599701119308766 0.7802935202575939 0.6690357392722762 0.49546171547605716 0.5967389960985566 0.7309031334227584 0.7870160221015348 0.6387424058442894 0.8360865543398621 1.0 14.843944433594249 -8.719345576212886 0.5686292710458817 1.0092423966834092 0.6328669868073254 0.6205953605762531 0.08698402468140125 0.8378381702932617 0.5913036194026431 0.10606943640859731 0.04312026800670306 1.908334157204614e-09 8.719345576212886 -0.37637540987608376 AAVQELSS(ph)SILAGEDPEER ddPTM_PC-9_AZD4547_30min_R2 2 AAVQELSSSILAGEDPEER 19 0 E7ES96;P49768-7;P49768-2;P49768 E7ES96 PSEN1 Presenilin;Presenilin-1;Presenilin-1 NTF subunit;Presenilin-1 CTF subunit;Presenilin-1 CTF12 1 AAVQELS(0.025)S(0.659)S(0.316)ILAGEDPEER;AAVQELS(0.029)S(0.793)S(0.178)ILAGEDPEER 165.66 9.1734e-08 9330500.0 22082.0 38585.0 39856.0 27736.0 30071.0 22826.0 30925.0 42481.0 29745.0 26432.0 True False 29103.616665866844 51056.846679200105 39327.48339855221 21341.893716928313 25896.16071324328 21398.68661159797 33677.26509033677 35916.537566266394 31317.259974378958 25506.623725274665 1.1410219156927421 2.001709329667477 1.5418537483493895 0.8367196672831498 1.0152719933521668 0.838946261256596 1.3203341003915687 1.4081259030248086 1.2278089139389508 1.0 14.638584323681211 -5.643077983545916 7.074176074743484 1.1063038778171224 1.6190046630560422 0.3972903349602357 0.26293865633473124 0.21169746402771797 12.190468722640922 0.07325314211302907 0.12745955458756625 2.2746889424209956e-06 5.643077983545916 0.5127007852389198 AAVQELSS(ph)SILAGEDPEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AAVQELSSSILAGEDPEER 19 0 E7ES96;P49768-7;P49768-2;P49768 E7ES96 PSEN1 Presenilin;Presenilin-1;Presenilin-1 NTF subunit;Presenilin-1 CTF subunit;Presenilin-1 CTF12 1 AAVQELSS(0.691)S(0.309)ILAGEDPEER;AAVQELS(0.001)S(0.99)S(0.009)ILAGEDPEER 185.96 6.8745e-11 6068800.0 27582.0 30981.0 30589.0 21565.6 45193.0 22811.0 23536.0 22995.0 19102.3 21746.0 True False 32251.08783066808 34056.58893370393 31318.357769428494 20357.349348618533 36337.75607066502 21614.751003529535 21306.499694116123 22391.40561521643 19381.63499949889 25688.377658758727 1.2554739057128321 1.3257586518739137 1.219164486969856 0.7924731417080159 1.414560177889446 0.8414214120742558 0.8294217710884301 0.871655108495411 0.7544904258634844 1.0 14.648828159723173 -6.1267812084448865 0.6044731230375217 0.8348140331138373 1.3373169654997799 0.4290076790237506 0.17818867458526796 0.9990702408478455 0.7234870444017172 0.12131198898122736 0.28509386856362273 7.468249037140597e-07 6.1267812084448865 0.5025029323859426 AAVQELSS(ph)SILAGEDPEER ddPTM_PC-9_Lapatinib_30min_R1 2 AAVQELSSSILAGEDPEER 19 0 E7ES96;P49768-7;P49768-2;P49768 E7ES96 PSEN1 Presenilin;Presenilin-1;Presenilin-1 NTF subunit;Presenilin-1 CTF subunit;Presenilin-1 CTF12 1 AAVQELSS(0.739)S(0.261)ILAGEDPEER;AAVQELS(0.025)S(0.971)S(0.005)ILAGEDPEER 273.01 1.1032999999999997e-91 6099100.0 49933.0 51646.0 22869.7 18707.4 19774.7 15555.6 14710.5 12292.9 29057.0 7264.099999999999 True False 49220.946263409256 51526.4168601208 20989.441545594927 20083.204602056994 18611.591024556044 14890.323249874693 15472.137710970705 12864.073011437793 25784.29467622512 8519.690006195166 5.77731657227174 6.047921558490147 2.463639114842474 2.3572694062170476 2.18453852323529 1.7477541130072887 1.8160446799965735 1.5099226617498491 3.026435780817829 1.0 13.056585222782081 -5.300591107937885 4.16079853071642 1.9969617893068976 5.970481312095532 0.9016273862826324 0.5166265036654012 0.05306478296676127 2.059472503391164 0.13285513880753289 0.31788061916665594 5.005055435699631e-06 5.300591107937885 3.973519522788634 AAVVT(ph)SPPPTTAPHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AAVVTSPPPTTAPHK 15 0 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;P35611-5;A0A0A0MSR2;D6RJE2;D6RAH3;D6RF25 P35611 ADD1 Alpha-adducin 1 AAVVT(0.587)S(0.413)PPPTTAPHK;AAVVT(0.567)S(0.433)PPPTTAPHK 85.57600000000001 0.012054 220580000.0 97549.0 114094.0 117169.0 116016.0 160775.0 165791.0 198255.0 158892.0 169044.0 143341.0 True False 114062.119019427 125420.49829902266 119962.7533259072 109515.9996489468 129272.29288299443 157096.62810162472 179474.8511580981 154721.2533599901 171515.94870017152 169327.58861326802 0.6736180438967725 0.7406973625867549 0.708465491703738 0.6467699714254683 0.7634449527196836 0.9277674677126719 1.0599268118558383 0.9137391882037739 1.0129238247873567 1.0 17.369457525714644 -6.754209186786501 2.8435038269419435 0.9902665890547804 0.6974229543007952 0.9195880233608672 0.04156315150054836 0.06691509596883037 1.1113023646959388 0.01488017735720622 0.013878360761430421 1.7611275591084158e-07 6.754209186786501 -0.2928436347539852 AAVVTS(ph)PPPTTAPHK ddPTM_PC-9_AZD4547_30min_R2 4 AAVVTSPPPTTAPHK 15 0 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;P35611-5;A0A0A0MSR2;D6RJE2;D6RAH3;D6RF25 P35611 ADD1 Alpha-adducin 1 AAVVT(0.146)S(0.854)PPPTTAPHK;AAVVT(0.029)S(0.971)PPPTTAPHK;AAVVT(0.052)S(0.948)PPPTTAPHK;AAVVT(0.424)S(0.576)PPPTTAPHK 123.42 1.9683e-05 704849000.0 293504.0 313339.0 380123.0 416084.0 325090.0 338495.0 291876.0 378625.0 287835.0 281260.0 True False 386832.16673754936 414619.7040718898 375082.3206520439 320162.26223371783 279956.8649618662 317328.85413970205 317852.39856126567 320117.20618694543 303049.3704732015 271413.1730088806 1.4252519966114257 1.5276329423344663 1.3819606340174628 1.1796120972479187 1.0314785456367883 1.1691726330811478 1.1711015903817816 1.1794460918684713 1.1165610243364488 1.0 18.05013121794002 -5.713708473086629 2.9156961696885726 1.1244684983789488 1.4737852159414901 0.8585590594726618 0.061321253427295455 0.0868587807566783 1.4983627294339097 0.017383250303355267 0.03181484826789454 1.9332656161107686e-06 5.713708473086629 0.34931671756254135 AAVVTS(ph)PPPTTAPHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AAVVTSPPPTTAPHK 15 0 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;P35611-5;A0A0A0MSR2;D6RJE2;D6RAH3;D6RF25 P35611 ADD1 Alpha-adducin 1 AAVVT(0.05)S(0.95)PPPTTAPHK;AAVVT(0.287)S(0.713)PPPTTAPHK;AAVVT(0.214)S(0.786)PPPTTAPHK 131.61 5.1169e-06 222062800.0 97071.0 100126.0 112608.0 103537.0 146934.0 131978.0 157406.0 154515.0 131532.0 111447.0 True False 113503.20306035735 110065.84757031869 115293.0017882182 97736.15756148296 118143.33747454436 125056.84134600929 142495.36415924746 150459.1449721752 133455.40666590337 131651.45888603362 0.8621492235692836 0.8360397104721726 0.8757442018779571 0.7423856779748257 0.8973948217073477 0.9499085114906848 1.0823682879397565 1.1428596860625966 1.0137024518765976 1.0 17.006363983029175 -6.9288222204785965 2.1174126815912078 1.0710686596648737 0.8340107648006053 0.7935368870015334 0.052286387530770466 0.1309245007989016 1.1922878059796063 0.021786269117876653 0.01790041250986661 1.178088128120469e-07 6.9288222204785965 -0.23705789486426843 AAVVTS(ph)PPPTTAPHK ddPTM_PC-9_Lapatinib_30min_R1 4 AAVVTSPPPTTAPHK 15 0 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;P35611-5;A0A0A0MSR2;D6RJE2;D6RAH3;D6RF25 P35611 ADD1 Alpha-adducin 1 AAVVT(0.136)S(0.864)PPPTTAPHK;AAVVT(0.427)S(0.573)PPPTTAPHK;AAVVT(0.412)S(0.588)PPPTTAPHK;AAVVT(0.158)S(0.842)PPPTTAPHK 128.45 1.0159e-05 547267000.0 146201.0 192706.0 214799.0 171415.0 258791.0 322670.0 343019.0 355271.0 347196.0 284533.0 True False 144116.14693002045 192259.80109682144 197139.05536811828 184021.43092367717 243569.42218268182 308870.15628050745 360778.84541514236 371778.1876405496 308091.1303440366 333714.1499336086 0.43185506805357793 0.5761212137245931 0.590742272712555 0.5514343067571084 0.7298744216603917 0.9255530709199961 1.0811014321296182 1.1140618032364338 0.9232186600578082 1.0 18.34825333448491 -6.651533344340649 1.7334388392250906 1.0404261707621438 0.5373083761593337 0.9269906027410411 0.06303105713718049 0.08681513741111412 0.5371239530977321 0.02565542895827084 0.02544112397025225 2.230830921764652e-07 6.651533344340649 -0.5031177946028101 AAYEAELGDAR ddPTM_PC-9_AZD4547_30min_R2 3 AAYEAELGDAR 11 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ;; 157.34 0.00032924 15860100.0 41520.0 42884.0 50602.0 73231.0 55446.0 49303.0 48980.0 61901.0 42180.0 53447.0 False True 54722.4963303501 56745.41435767315 49930.98441724054 56348.724357671475 47748.279967626215 46220.075616034985 53339.1251131672 52335.62279347134 44409.54868782332 51575.83679800067 1.0610103437521232 1.1002325484299826 0.9681080815576046 1.0925411560138918 0.9257877900194761 0.896157551394817 1.0341882638195972 1.0147314332183577 0.8610533816786246 1.0 15.65440770302005 -6.264675225108632 24.997291016396247 0.9570416244930047 1.052429787701696 0.3995198754783583 0.06008357605687888 315.4184693740154 2436645.729023766 0.018557963053725028 0.021943785243448026 5.436567378867617e-07 6.264675225108632 0.09538816320869126 AAYEAELGDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAYEAELGDAR 11 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 117.31 0.0054123 5269600.0 15408.0 15126.0 17579.0 20475.0 19106.0 13616.0 14272.0 16399.0 17920.0 10738.0 False True 18016.27007812825 16627.60931574854 17998.15002872875 19327.85213084564 15362.31645356859 12901.952990401916 12920.052839667977 15968.543626176755 18182.046098690742 12684.714398038766 1.4203134191900937 1.3108382888241774 1.4188849243236816 1.5237120461958524 1.2110888721265824 1.017126013684371 1.0185529160724025 1.2588808171073773 1.4333823788340034 1.0 13.630803416399335 -6.420567719927678 5.790234187710457 1.1497820228693885 1.4092476199510764 0.4920409208899166 0.13149429795889073 0.2240642146405811 10.521022834353754 0.04404281270297315 0.04981686748131231 3.7969272852773173e-07 6.420567719927678 0.2594655970816879 AAYEAELGDAR ddPTM_PC-9_Lapatinib_30min_R1 4 AAYEAELGDAR 11 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ;;; 145.46 0.00094045 39398600.0 98576.0 102544.0 128468.0 101775.0 115135.0 110105.0 104019.0 111330.0 117207.0 100500.0 False True 97170.28816337566 102306.56566828438 117905.85694082096 109259.87301144724 108362.98566411935 105396.06581729116 109404.59485112419 116502.7982301468 104005.91341557362 117871.29109216784 0.8243762095334536 0.8679515149137305 1.0002932507850966 0.9269421926159525 0.9193331527978802 0.8941623090806577 0.928169988106576 0.9883899391502299 0.8823684923773986 1.0 16.846852850579012 -5.047479231211493 6.279852451558665 0.9384324966685731 0.834034834008922 0.49396375528303105 0.03990858274602985 0.14541876102953577 14.598071962756336 0.009879607049756886 0.028256812364953834 8.964390543462556e-06 5.047479231211493 -0.10439766265965111 AAYEHFHR ddPTM_PC-9_AZD4547_30min_R2 1 AAYEHFHR 8 0 K7EQ71;K7EKI8;O60437 K7EQ71 PPL Periplakin 0 141.52 0.0018713 1649600.0 10721.0 8860.7 9884.3 15713.0 14536.0 11226.0 7709.9 12009.0 10509.0 10929.0 False True 14130.054989346909 11724.747994567533 9753.22772371311 12090.61061343001 12517.927309624043 10524.036445360493 8396.066163944623 10153.284989366852 11064.484285451283 10546.379036528702 1.3398015508835495 1.1117320887062188 0.9247939686153499 1.1464229164865656 1.1869407752430134 0.9978814917337199 0.7961088952771181 0.9627271079675479 1.0491263633829258 1.0 13.364460132725704 -6.918250101511942 5.676374131739071 0.941979011119975 1.1273475970792528 0.39127216955077093 0.11273772015360413 0.23372370673594287 12.395725967196581 0.04215218939752234 0.037039074344087056 1.2071184794994708e-07 6.918250101511942 0.18536858595927785 AAYEHFHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AAYEHFHR 8 0 K7EQ71;K7EKI8;O60437 K7EQ71 PPL Periplakin 0 95.09899999999999 0.0054811999999999994 1099000.0 6661.0 6161.9 8160.4 8509.0 9778.6 9033.1 9547.0 7191.3 6518.8 6568.2 False True 7788.575739253141 6773.612709421586 8354.974884489337 8032.268316550204 7862.553526267448 8559.388334136274 8642.639045705591 7002.535994812179 6614.1251176420255 7758.962666157406 1.0038166278624976 0.8730049364673886 1.076815966769834 1.0352245090165064 1.0133511223815883 1.1031614279406343 1.1138910467249126 0.9025093038990166 0.8524496639855137 1.0 12.921648068978229 -7.788585741495047 24.977334951062403 0.9081094706691184 1.0292059594284513 0.33815925114496914 0.0719804986322337 257.4611784640832 236886.07599101897 0.04133972365684988 0.019867051472226966 1.6271000503046578e-08 7.788585741495047 0.12109648875933288 AAYLQETGKPLDETLK ddPTM_PC-9_Lapatinib_30min_R1 2 AAYLQETGKPLDETLK 16 1 P04083;Q5T3N0;Q5T3N1 P04083;Q5T3N1 ANXA1 Annexin A1;Annexin 0 ; 90.229 0.0046178 12228200.0 63223.0 50283.0 57784.0 49902.0 58360.0 41584.0 62257.0 55631.0 37959.0 58846.0 False True 62321.42842632177 50166.572802878334 53033.222572690385 53571.95954819205 54927.379540174574 39805.54925703856 65480.362834159445 58215.81935095024 33683.65769400935 69017.45269263381 0.9029807098773626 0.7268679275413562 0.7684030705808791 0.7762088784524172 0.7958476790615736 0.5767461374488975 0.94875079098867 0.8434941754546031 0.48804550704034294 1.0 16.07467360708233 AAYLQETGKPLDETLKK ddPTM_PC-9_Lapatinib_30min_R1 1 AAYLQETGKPLDETLKK 17 2 P04083;Q5T3N0;Q5T3N1 P04083;Q5T3N1 ANXA1 Annexin A1;Annexin 0 90.853 0.0093791 22770000.0 137260.0 117040.0 158580.0 118290.0 142990.0 116630.0 169550.0 140400.0 135450.0 163580.0 False True 135302.64722959884 116769.001070916 145542.16453650242 126989.44120387218 134579.60932915626 111642.0067778091 178328.4693854787 146923.49655539927 120194.19464826715 191854.58504335082 0.7052354114916061 0.6086328405679294 0.758606652552068 0.6619046460379254 0.7014667348124471 0.5819095058509175 0.9294980849437828 0.7658065431284894 0.6264859118227927 1.0 17.549653718086205 -14.522878744979408 0.19665200148555115 2.2984326944439597 0.6583254413121602 0.46792104203955653 0.09456950197558696 124.92631642005908 1.228314053572573 63.69617932680805 0.23586314351574583 3.0000000020787454e-15 14.522878744979408 -1.6401072531317995 ACANPAAGSVILLENLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ACANPAAGSVILLENLR 17 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 ; 199.33 8.9541e-12 10441600.0 31890.0 30727.0 31248.0 41316.0 43242.0 34312.0 41851.0 35608.0 32768.0 28183.0 False True 37288.34714378961 33777.37349233145 31993.070828699903 39001.1984682793 34769.04051529432 32512.618317176144 37886.570304998924 34673.32772979461 33247.17000903448 33292.354803494774 1.1200273265102703 1.014568470500193 0.9609735033023713 1.1714761151165327 1.0443550995571071 0.9765791128046978 1.137996111378156 1.041480181694894 0.9986427876692114 1.0 15.022903296983928 -8.186370342437073 4.578193423710893 0.9991365088221411 1.0575660844357961 0.12209754403516138 0.06430499408124259 0.48120860715084607 18.31977956711232 0.04813560581225433 0.016540568584430662 6.510729580785805e-09 8.186370342437073 0.05842957561365503 ACANPAAGSVILLENLR ddPTM_PC-9_Lapatinib_30min_R1 2 ACANPAAGSVILLENLR 17 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 ; 177.63 1.8112000000000002e-05 64650000.0 45471.0 48360.0 50612.0 45300.0 46908.0 50150.0 41919.0 47063.0 50377.0 44873.0 False True 44822.57520163988 48248.02539122952 46450.8767279698 48631.51311637006 44148.9636646763 48005.201405359854 44089.36070875773 49249.71879192845 44703.011766672156 52629.23826048592 0.8516668050522157 0.9167532532473338 0.8826059100088697 0.9240398440819281 0.8388676166309513 0.9121393923233391 0.8377351101024783 0.9357862743171257 0.8493949987536722 1.0 15.683576893404032 -11.683495116422565 2.3852170661181527 1.2775205770985063 0.8851439705869805 0.49276633568329 0.03549603440254188 4172520.2330270982 990295.6803444183 6266964.377155401 0.007942691268877753 2.072549364963663e-12 11.683495116422565 -0.39237660651152584 ACAS(ph)PSAQVEGSPVAGSDGSQPAVK ddPTM_PC-9_AZD4547_30min_R2 2 ACASPSAQVEGSPVAGSDGSQPAVK 25 0 F8WDB4;Q9UFC0 F8WDB4 LRWD1 Leucine-rich repeat and WD repeat-containing protein 1 1 ACAS(0.801)PS(0.199)AQVEGSPVAGSDGSQPAVK;ACAS(0.76)PS(0.24)AQVEGSPVAGSDGSQPAVK 152.64 1.7896e-07 26076000.0 101935.0 105543.0 134386.0 190857.0 165648.0 139201.0 114567.0 155016.0 133926.0 138789.0 True False 134348.20962028485 139657.71074414448 132603.9538337473 146857.8673612557 142650.6344926118 130496.73946469124 124763.24105431276 131061.83911330608 141005.05494465216 133930.0393540839 1.0031223037655905 1.0427661443070122 0.990098669971785 1.0965267244713728 1.0651130633619275 0.9743649751321605 0.9315553228836438 0.9785843395954295 1.0528262040740788 1.0 17.031120055462566 -6.7718427941841 24.99977969142079 0.9826332516953846 1.0401262372787767 0.299000312238872 0.039505373219738016 262.4195873653196 630600.2899042744 0.014513805404495598 0.012935503457420665 1.6910529478219494e-07 6.7718427941841 0.05749298558339211 ACAS(ph)PSAQVEGSPVAGSDGSQPAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ACASPSAQVEGSPVAGSDGSQPAVK 25 0 F8WDB4;Q9UFC0 F8WDB4 LRWD1 Leucine-rich repeat and WD repeat-containing protein 1 1 ACAS(0.938)PS(0.062)AQVEGSPVAGSDGSQPAVK;ACAS(0.938)PS(0.062)AQVEGSPVAGSDGSQPAVK 176.52 5.097100000000001e-15 20690700.0 80976.0 100659.0 98672.0 98423.0 120115.0 97861.0 104551.0 88206.0 92434.0 85192.0 True False 94683.63745109767 110651.76028784442 101024.71469564362 92908.67840167144 96579.32800274213 92728.99688555537 94647.17239630922 85890.68596198244 93785.67238205257 100636.63522049884 0.9408466135979416 1.0995176860335407 1.0038562445405144 0.923209308400513 0.9596835962483544 0.9214238600325069 0.9404842698579253 0.8534733476908539 0.9319237688796377 1.0 16.618796066156044 -5.688508901426321 4.502652105370001 0.92758937859962 1.0268763464951247 0.35814813393882927 0.049806433923493154 0.19074192715336014 7.293262052401716 0.013252083459039646 0.023295783182560398 2.048760057543701e-06 5.688508901426321 0.09928696789550473 ACAS(ph)PSAQVEGSPVAGSDGSQPAVK ddPTM_PC-9_Lapatinib_30min_R1 2 ACASPSAQVEGSPVAGSDGSQPAVK 25 0 F8WDB4;Q9UFC0 F8WDB4 LRWD1 Leucine-rich repeat and WD repeat-containing protein 1 1 ACAS(0.948)PS(0.052)AQVEGSPVAGSDGSQPAVK;ACAS(0.948)PS(0.052)AQVEGSPVAGSDGSQPAVK 183.79 6.454199999999999e-21 30707000.0 209992.0 202124.0 218501.0 216331.0 212378.0 224268.0 186303.0 189080.0 202801.0 165139.0 True False 206997.47557218323 201655.99429646114 200536.69121825154 232240.70339906018 199886.34359121317 214676.58043424223 195948.8577524198 197865.3470704768 179959.41579079526 193683.05611611373 1.0687433362683385 1.041164871828373 1.0353858269255574 1.1990759958879986 1.0320280338378207 1.108391124856801 1.0116985020875946 1.0215934787390786 0.9291438259984338 1.0 17.563338223285186 -7.631415745898719 1.7516544970840882 0.971555214329886 1.0801518810555846 0.43618967935560304 0.05076076328819407 0.3541043270742776 2.1190283740700977 0.03462374124049394 0.015496658459046408 2.3365993637556538e-08 7.631415745898719 0.10859666672569857 ACASPSAQVEGS(ph)PVAGSDGSQPAVK ddPTM_PC-9_AZD4547_30min_R2 1 ACASPSAQVEGSPVAGSDGSQPAVK 25 0 F8WDB4;Q9UFC0 F8WDB4 LRWD1 Leucine-rich repeat and WD repeat-containing protein 1 1 ACASPSAQVEGS(0.992)PVAGS(0.008)DGSQPAVK 94.802 1.5696000000000002e-06 5279000.0 19753.0 16133.0 28289.0 36243.0 30550.0 28973.0 20976.0 32508.0 23498.0 29588.0 True False 26034.043112076248 21347.67675199004 27913.86937629575 27887.736298768123 26308.659831385132 27161.313729861893 22842.823364103628 27484.635559525133 24740.05630788223 28552.133125886292 0.9118072893990865 0.7476736206667355 0.9776456719791674 0.9767303961427735 0.9214253700552008 0.951288424234635 0.8000391166358629 0.9626123357699908 0.8664871447188683 1.0 14.80131091270944 ACASPSAQVEGS(ph)PVAGSDGSQPAVK ddPTM_PC-9_Lapatinib_30min_R1 1 ACASPSAQVEGSPVAGSDGSQPAVK 25 0 F8WDB4;Q9UFC0 F8WDB4 LRWD1 Leucine-rich repeat and WD repeat-containing protein 1 1 ACASPSAQVEGS(1)PVAGSDGSQPAVK 130.19 1.2207e-07 7236600.0 68837.0 65790.0 73979.0 57210.0 68036.0 69791.0 57698.0 56416.0 73948.0 59077.0 True False 67855.37175684035 65637.66729712566 67896.73218719839 61417.414246965374 64034.256243922595 66806.20162076715 60685.32012151775 59037.29331673363 65619.19753303831 69288.38073484559 0.9793181921296572 0.947311318304716 0.9799151238218022 0.886402793593907 0.9241701936861593 0.9641761131122794 0.8758368932555917 0.8520518547353406 0.947044754648711 1.0 16.08032582048809 -5.750562698029682 24.98094373693734 0.9152201180644632 0.966694531153558 0.20041916127334292 0.042141178934895815 314.81302926762237 723037.7235571323 0.011386415154875023 0.019478575892982224 1.775976856355149e-06 5.750562698029682 0.05147441308909473 ACFHCETCK ddPTM_PC-9_AZD4547_30min_R2 2 ACFHCETCK 9 0 Q14847;Q14847-2;F6S2S5;K7ESD6 Q14847 LASP1 LIM and SH3 domain protein 1 0 ; 144.12 0.00047535 9171800.0 81775.0 74774.0 105604.0 114139.0 105088.0 107012.0 96668.0 104487.0 95132.0 102526.0 False True 107777.74897433493 98943.2332147339 104203.62195957218 87826.01697997113 90498.34515092 100320.52272322455 105271.26472926982 88340.93502239788 100160.48330417268 98936.59594648548 1.0893618073602573 1.000067086078563 1.0532363779317373 0.8877000076642617 0.9147105202595639 1.0139880169061772 1.0640275594908353 0.892904533224301 1.0123704211366762 1.0 16.59421664193654 -4.7115424081472455 1.2923026141103025 0.9726786597773901 1.1452871484621712 0.2398220974754457 0.05920440511739463 2.421077367472249 3.164657266562893 0.01808588426961007 0.5803289449951742 1.942931958430765e-05 4.7115424081472455 0.17260848868478107 ACFHCETCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ACFHCETCK 9 0 Q14847;Q14847-2;F6S2S5;K7ESD6 Q14847 LASP1 LIM and SH3 domain protein 1 0 ; 126.24 0.0011756 11229300.0 69528.0 75723.0 80433.0 78495.0 94128.0 91465.0 88066.0 62718.0 73372.0 71041.0 False True 81297.71715940432 83240.27900412711 82350.82776385112 74097.1796342236 75684.29410350161 86668.41438506985 79723.75093737397 61071.71895521398 74444.92669381337 83920.17093975336 0.9687506144115018 0.991898349014156 0.9812995712672121 0.8829483877888938 0.9018605807873733 1.0327483060930545 0.94999509706204 0.7277358741208669 0.8870921717647321 1.0 16.35672999614055 -7.564075494116186 24.98044825476235 0.8522213264383462 0.9591362959112989 0.21300420552919708 0.07396754085737443 181.31571815521886 109942.36791741292 0.033908959944305726 0.01957736388413383 2.7285034413902316e-08 7.564075494116186 0.10691496947295265 ACFHCETCK ddPTM_PC-9_Lapatinib_30min_R1 3 ACFHCETCK 9 0 Q14847;Q14847-2;F6S2S5;K7ESD6 Q14847 LASP1 LIM and SH3 domain protein 1 0 ;; 137.14 0.0008075 25867100.0 336936.0 354930.0 391940.0 374140.0 381840.0 337401.0 342629.0 347160.0 362300.0 345600.0 False True 332131.2308535046 354108.18139183347 359716.20613215177 401655.50369445194 359380.9219263236 322971.1457501459 360368.65312342765 363290.32096988923 321493.958811865 405336.49951694603 0.8193963071406529 0.8736153339603929 0.8874508132399584 0.9909186667697558 0.8866236382724247 0.7967975894967321 0.8890604560726504 0.8962684618898995 0.7931532422937506 1.0 18.628760566676185 -6.534464782781802 24.905990214098843 0.8663660856500012 0.8970469996298317 0.005907601374231297 0.06704457874619603 813.6560473143413 1749067.153944066 0.021871582919313782 0.021887492826621727 2.921024618364078e-07 6.534464782781802 0.030680913979830526 ACGNFGIPCELR ddPTM_PC-9_Lapatinib_30min_R1 2 ACGNFGIPCELR 12 0 E9PBS1;P22234;P22234-2;D6RF62 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 0 ; 108.31 0.0035183 2483000.0 34333.0 31081.0 33908.0 26629.0 32841.0 37478.0 29645.0 28427.0 28979.0 24444.0 False True 33843.40512409889 31009.033854110938 31120.215128665142 28587.385491739933 30909.35694789024 35875.1533054851 31179.87304590099 29747.822197865604 25715.079857601544 28669.11283041737 1.1804831675220762 1.0816181874037958 1.0854962730359483 0.9971492895800136 1.0781413827042465 1.2513520567480647 1.087577185605121 1.037626185847779 0.8969611305976077 1.0 14.807209640425038 -7.983798227171172 3.2473682190079844 0.949823032529719 1.1065442427400418 0.4679246849693942 0.06805354347818253 0.23323763065921804 4.975551040496643 0.050648819806367776 0.0193004518646148 1.038010562588158e-08 7.983798227171172 0.15672121021032281 ACKVDS(ph)PTVTTTLK ddPTM_PC-9_AZD4547_30min_R2 1 ACKVDSPTVTTTLK 14 1 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;G3V3H3;H0YJT3;F8W6L3;E7EVH7;G5E9S8;H0YJU9;H0YJL0;G3V2E7;Q07866-8;Q07866-2;Q07866-3;Q07866-5;Q07866-10;Q07866 Q07866-6 KLC1 Kinesin light chain 1 1 ACKVDS(0.734)PT(0.261)VT(0.004)T(0.001)TLK 97.417 0.013064 7908100.0 40305.0 26051.0 42642.0 72857.0 70275.0 44782.0 35815.0 55197.0 36307.0 52119.0 True False 53121.15160392007 34471.47629492917 42076.539218212136 56060.94427942913 60518.529284798315 41981.774460728106 39002.46561715156 46667.57195087702 38226.11389779043 50294.329673788976 1.056205579206761 0.6853948848411449 0.8366060247968756 1.1146573508990505 1.203287322394471 0.8347218211878669 0.7754843512205671 0.9278893317311265 0.7600481832788413 1.0 15.618108135193832 ACKVDS(ph)PTVTTTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ACKVDSPTVTTTLK 14 1 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;G3V3H3;H0YJT3;F8W6L3;E7EVH7;G5E9S8;H0YJU9;H0YJL0;G3V2E7;Q07866-8;Q07866-2;Q07866-3;Q07866-5;Q07866-10;Q07866 Q07866-6 KLC1 Kinesin light chain 1 1 ACKVDS(0.635)PT(0.258)VT(0.076)T(0.023)T(0.007)LK 56.424 0.033477999999999994 31405000.0 99142.0 46156.0 65871.0 110850.0 111380.0 129740.0 104630.0 121420.0 117800.0 93586.0 True False 115924.7824562432 50738.06264562274 67441.61445715872 104639.43388054866 89555.88854802004 122936.20600578332 94718.68894439879 118232.85365512442 119522.60214429525 110552.40097363168 1.0485957919981577 0.458950345707322 0.6100420602646568 0.9465143493853801 0.8100763778923299 1.1120175131710197 0.8567764074792961 1.0694734136377972 1.081139813261976 1.0 16.754370832337557 -6.183278528720341 1.536131643932062 1.011668040285835 0.6934854565011208 0.35365640751939575 0.16657190658241244 0.40384181512746736 1.901476552343058 0.05904749599799978 0.08621239462327394 6.55724591581637e-07 6.183278528720341 -0.3181825837847141 ACKVDS(ph)PTVTTTLK ddPTM_PC-9_Lapatinib_30min_R1 1 ACKVDSPTVTTTLK 14 1 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;G3V3H3;H0YJT3;F8W6L3;E7EVH7;G5E9S8;H0YJU9;H0YJL0;G3V2E7;Q07866-8;Q07866-2;Q07866-3;Q07866-5;Q07866-10;Q07866 Q07866-6 KLC1 Kinesin light chain 1 1 ACKVDS(0.982)PT(0.018)VTTTLK 199.84 2.6154e-07 8316400.0 41368.0 17920.0 21974.0 20497.0 17801.0 16152.0 15032.0 13407.0 20812.0 10434.0 True False 40778.08473403792 17878.50734100153 20167.38254209294 22004.41775598756 16753.980178112542 15461.216612150993 15810.283407859108 14029.938164659814 18467.9333999242 12237.50299756892 3.3322226554010914 1.4609604054481735 1.647998169732776 1.7981133700526095 1.3690685249630468 1.2634290357454858 1.2919533838725066 1.1464706621479053 1.5091259551554763 1.0 13.579021592765736 -3.07750586824128 1.3840792294637554 1.3642822906745866 199.99999999977348 0.8604451086764928 0.23310513677679376 51.97475173398867 1.2826169308251594 0.06854763840058176 31775.342283864404 0.0008365542920533672 3.07750586824128 198.63571770909888 up ACLISLGYDVENDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ACLISLGYDVENDR 14 0 O43707;O43707-2;F5GXS2;O43707-3 O43707 ACTN4 Alpha-actinin-4 0 140.78 2.4361e-05 0.0 9361.1 9564.9 9810.5 13545.0 13738.0 8223.7 11564.0 9569.9 10354.0 8779.6 False True 10945.749339847258 10514.44005977808 10044.41952652844 12786.117563482501 11046.137519058171 7792.4346950035415 10468.574203890172 9318.700265147205 10505.40766215646 10371.271980724641 1.0553912152906897 1.013804293178264 0.9684848247347415 1.2328398664354703 1.0650706624595123 0.7513480226423571 1.0093818987050354 0.8985108367099353 1.0129333876964286 1.0 13.340305223338735 -6.587810834695079 24.999999616381594 0.9300458489528529 1.0682402455842015 0.3251433701339752 0.09547672901614665 70.49230398951158 27139.883889793902 0.03133567604956614 0.03133567498524635 2.583385188658465e-07 6.587810834695079 0.13819439663134858 ACLISLGYDVENDR ddPTM_PC-9_Lapatinib_30min_R1 2 ACLISLGYDVENDR 14 0 O43707;O43707-2;F5GXS2;O43707-3 O43707 ACTN4 Alpha-actinin-4 0 ; 179.94 0.00014831 19972400.0 109013.0 97062.0 104137.0 105360.0 98234.0 88430.0 92023.0 85471.0 114881.0 108506.0 False True 107458.45462946426 96837.2589024714 95575.25784044497 113108.52587065693 92456.06925547481 84648.05504039837 96787.50066800283 89442.2946872258 101941.89202943927 127261.11752484285 0.84439345433602 0.7609335890325467 0.7510169618130814 0.8887909211435051 0.726506815700611 0.6651525358786362 0.7605425958098222 0.7028249981363367 0.8010450796924601 1.0 16.957432170009653 -8.556937787851432 20.493206815571995 1.0000000017159674 0.761165588010452 0.5749876495902159 0.06094415563084589 828.0518165907844 498236.1503927017 0.06097985852194838 0.0157449317643356 2.773717407790181e-09 8.556937787851432 -0.2388344137055154 ACPDSLGS(ph)PAPSHAYHGGVL ddPTM_PC-9_AZD4547_30min_R2 4 ACPDSLGSPAPSHAYHGGVL 20 0 E9PNA7;Q5XXA6-2;Q5XXA6 E9PNA7 ANO1 Anoctamin;Anoctamin-1 1 ACPDSLGS(1)PAPSHAYHGGVL;ACPDS(0.011)LGS(0.988)PAPS(0.001)HAYHGGVL;ACPDS(0.005)LGS(0.995)PAPSHAYHGGVL;ACPDS(0.101)LGS(0.881)PAPS(0.016)HAY(0.002)HGGVL 105.96 7.6947e-05 33276300.0 15673.4 29287.000000000004 89952.0 104156.0 94410.0 64852.0 63829.0 122722.0 66519.6 60763.0 True False 20657.215173027682 38753.45001150017 88759.17770640727 80144.4433941586 81302.80113522326 60796.79418800276 69509.65734684255 103758.13477101157 70035.69025354502 58635.70586481778 0.3522975441048164 0.6609189646466381 1.513739391336704 1.3668197937094566 1.3865749535387797 1.0368561832984031 1.1854493149122178 1.7695384278347686 1.1944205193847148 1.0 15.839491832366772 -5.1099498620739805 3.9707241568138905 1.323757598932715 0.40803314111851224 0.6898351735117081 0.2180600705822709 0.11919138654555017 3.192811483205995 0.05666801723805869 0.18013549955914449 7.763367370792771e-06 5.1099498620739805 -0.9157244578142028 ACPDSLGS(ph)PAPSHAYHGGVL ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ACPDSLGSPAPSHAYHGGVL 20 0 E9PNA7;Q5XXA6-2;Q5XXA6 E9PNA7 ANO1 Anoctamin;Anoctamin-1 1 ACPDS(0.001)LGS(0.999)PAPSHAYHGGVL;ACPDS(0.011)LGS(0.989)PAPSHAYHGGVL 64.538 0.0038768 13534800.0 21637.8 28319.1 57508.0 41476.0 123007.0 52429.0 50617.0 50654.0 53608.0 38726.1 True False 25300.65217396959 31130.43309358818 58879.20882030453 39152.234187006274 98904.66136313777 49679.53094402042 45822.191324654836 49324.386172349354 54391.915583627946 45746.83537436105 0.5530579758561707 0.6804936962051658 1.2870662711087455 0.855845740292437 2.162000071781341 1.085966505387244 1.0016472385396087 1.0782032411359619 1.1889765737568823 1.0 15.481384325183754 -5.192876166368181 4.185856555771292 1.2211241541684472 0.5825350915680375 0.32469241624202294 0.3412777578500273 0.25828640900097793 8.82876646741367 0.08979296467117752 0.260582364403959 6.413924355332737e-06 5.192876166368181 -0.6385890626004097 ACPDSLGS(ph)PAPSHAYHGGVL ddPTM_PC-9_Lapatinib_30min_R1 2 ACPDSLGSPAPSHAYHGGVL 20 0 E9PNA7;Q5XXA6-2;Q5XXA6 E9PNA7 ANO1 Anoctamin;Anoctamin-1 1 ACPDS(0.001)LGS(0.999)PAPSHAYHGGVL;ACPDS(0.001)LGS(0.999)PAPSHAYHGGVL 87.208 0.00041807 15617100.0 102050.0 75411.0 62940.0 23625.0 60961.0 38083.0 32737.0 29535.0 110194.0 16282.2 True False 100594.74828632202 75236.39046273804 57765.31615542596 25362.46131068967 57375.39383393736 36454.27886580896 34431.96167662877 30907.30392281849 97782.79132573746 19096.55657533224 5.267690428350006 3.9397883155502385 3.0249074448345126 1.3281169937962187 3.0044889824823904 1.9089451400310757 1.8030455669220422 1.618475236668722 5.120441004115227 1.0 14.221024899509207 -5.066627644880123 1.7658411171277884 2.2779486394581645 5.454526527111456 0.4312795226341192 1.1046418568242788 0.4910926936987761 2.298512689279694 0.30096856694709734 2.1773168531166194 8.577729668736315e-06 5.066627644880123 3.1765778876532917 ACPEEPAAPS(ph)PEPR ddPTM_PC-9_AZD4547_30min_R2 1 ACPEEPAAPSPEPR 14 0 O94819 O94819 KBTBD11 Kelch repeat and BTB domain-containing protein 11 1 ACPEEPAAPS(1)PEPR 109.07 0.00062469 4865000.0 16315.0 13331.0 13516.0 25426.0 21719.0 20465.0 19255.0 20979.0 13912.0 16513.0 True False 21502.830626918632 17639.985048086477 13336.769008802486 19564.42852778409 18703.69174722925 19185.320314831868 20968.65769812239 17737.177599461003 14647.35991808909 15934.884896166017 1.3494186350911315 1.1070042339829333 0.8369542105705047 1.227773445197044 1.1737575683229076 1.203982359448854 1.3158964018100636 1.1131035909602727 0.919200861100245 1.0 13.959900977558831 -10.296926077046459 5.531759104670093 0.9999999770509499 1.138816051045174 0.06984683269227565 0.15169587966623546 4.413043788889015e-08 9.75983428285312e-09 0.15096430639776498 0.03661421640882291 5.0474720523768217e-11 10.296926077046459 0.13881607399422402 ACPGPPPPS(ph)PEPLAR ddPTM_PC-9_AZD4547_30min_R2 2 ACPGPPPPSPEPLAR 15 0 A0A087WSV0;Q9HB09;Q9HB09-3 A0A087WSV0 BCL2L12 Bcl-2-like protein 12 1 ACPGPPPPS(1)PEPLAR;ACPGPPPPS(1)PEPLAR 159.41 7.4219e-05 54719000.0 43489.0 52551.0 79881.0 83834.0 82344.0 58148.0 57467.0 72948.0 58150.0 62829.0 True False 57317.597372605844 69537.08305918476 78821.72574668188 64507.366522388525 70911.95696090274 54511.996367791 62581.45167166962 61675.56277827732 61223.69028442215 60629.375833659244 0.9453766690566058 1.1469206486631895 1.3000583407445028 1.0639622400100046 1.1695973442882612 0.8991020543795192 1.0321968651527278 1.0172554463943082 1.0098024174352949 1.0 15.887729349830582 -6.745397447272875 24.995809345323458 0.9952826503914688 1.1327048471259649 0.35391401383599663 0.0898426490235053 276.1540136525372 430289.8361179126 0.03011281536879273 0.030021469296841366 1.797225420376554e-07 6.745397447272875 0.13742219673449607 ACPGPPPPS(ph)PEPLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ACPGPPPPSPEPLAR 15 0 A0A087WSV0;Q9HB09;Q9HB09-3 A0A087WSV0 BCL2L12 Bcl-2-like protein 12 1 ACPGPPPPS(1)PEPLAR;ACPGPPPPS(1)PEPLAR 132.23 7.2814e-06 37701000.0 82472.0 86783.0 111991.0 98239.0 153378.0 113042.0 126002.0 109310.0 101761.0 97812.0 True False 96432.88070375098 95398.24271113338 114661.29016823265 92734.9873251352 123324.68193318539 107113.87852093233 114066.1783845181 106440.7283235185 103249.06211210208 115544.54132063396 0.8345948636046036 0.8256404120935928 0.9923557517966141 0.8025908127308007 1.0673345579429987 0.9270353864982103 0.9872052550538634 0.9212094929534357 0.8935866717025416 1.0 16.818089578503084 -5.078864825660885 1.047632221485525 0.9524658177286082 0.7868165849815658 0.28347820776412314 0.06996876924271432 1.5299422892160026 1.9071275892685635 0.02246424897969921 0.25350064091462626 8.339407086233764e-06 5.078864825660885 -0.16564923274704235 ACPGPPPPS(ph)PEPLAR ddPTM_PC-9_Lapatinib_30min_R1 2 ACPGPPPPSPEPLAR 15 0 A0A087WSV0;Q9HB09;Q9HB09-3 A0A087WSV0 BCL2L12 Bcl-2-like protein 12 1 ACPGPPPPS(1)PEPLAR;ACPGPPPPS(1)PEPLAR 174.21 7.0893e-05 52266000.0 106551.0 98992.0 69228.0 51569.0 69346.0 59495.0 54045.0 47202.0 81035.0 43550.0 True False 105031.56320093985 98762.79010605036 63536.34106780783 55361.556289141015 65267.204619481585 56950.537539618825 56843.18565578405 49395.17723937288 71907.98496361989 51077.559473272646 2.0563152250040395 1.933584750808816 1.2439188896849014 1.0838723866223494 1.2778058562808576 1.1149815716903884 1.1128798290671735 0.967062204004087 1.40781951418895 1.0 15.640401973111583 -5.260052201368149 3.3295099389017486 1.140272903711642 2.0385207919482404 0.8881841146597872 0.12063883342323825 0.06613471680922989 1.5375308003334014 0.03063874659971948 0.08626807291479266 5.494748240626468e-06 5.260052201368149 0.8982478882365985 ACQS(ph)IYPLHDVFVR ddPTM_PC-9_AZD4547_30min_R2 1 ACQSIYPLHDVFVR 14 0 D6RAT0;P61247;D6RG13;D6R9B6;D6RB09;H0Y9Y4 D6RAT0 RPS3A 40S ribosomal protein S3a 1 ACQS(0.999)IY(0.001)PLHDVFVR 71.558 0.014063999999999998 2340300.0 8034.6 7639.1 9753.1 12670.0 6550.9 8740.4 7574.0 9056.2 6231.3 7492.5 True False 10589.435669938119 10108.289684257552 9623.767521437665 9749.127249548661 5641.420611765006 8193.861406291546 8248.07132721781 7656.772380773091 6560.67379654892 7230.189855539511 1.4646137766112566 1.3980669783536797 1.3310532245656428 1.3483915975013063 0.7802589868982144 1.1332844046984056 1.140782122187073 1.059000183087412 0.9073999338374729 1.0 12.819817815662702 -6.12991057944046 7.204400231297219 1.020318026614255 1.3881975722097009 0.762459373134105 0.10441480509582954 0.13387287122438193 7.233568903198916 0.03161899126536449 0.040986646878133706 7.414628916433413e-07 6.12991057944046 0.3678795455954458 ACQS(ph)IYPLHDVFVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ACQSIYPLHDVFVR 14 0 D6RAT0;P61247;D6RG13;D6R9B6;D6RB09;H0Y9Y4 D6RAT0 RPS3A 40S ribosomal protein S3a 1 ACQS(0.991)IY(0.009)PLHDVFVR 54.974 0.043312 1767100.0 7720.5 7573.4 7555.5 8448.0 10298.0 8192.1 11824.0 9529.7 7570.4 7517.3 True False 9027.42816317428 8325.237101143064 7735.651774393311 7974.6859487855445 8280.180824811549 7762.491854632157 10703.945121653178 9279.555472551783 7681.102778210282 8880.126983085944 1.0165877335277864 0.9375132942355686 0.8711194996566463 0.8980373776157705 0.9324394617985623 0.8741419879938027 1.2053819885730324 1.0449800425406792 0.8649766825227326 1.0 13.116364591480545 ACQSIYPLHDVFVR ddPTM_PC-9_AZD4547_30min_R2 1 ACQSIYPLHDVFVR 14 0 D6RAT0;P61247;D6RG13;D6R9B6;D6RB09;H0Y9Y4 D6RAT0 RPS3A 40S ribosomal protein S3a 0 99.069 0.0019279 7918900.0 43716.0 34976.0 50480.0 80123.0 65411.0 58120.0 50532.0 59862.0 47372.0 65981.0 False True 57616.77865071254 46281.3080070417 49810.60221695393 61651.880238010024 56329.81172604694 54485.747212217335 55029.2501065448 50611.70339191256 49875.987208145205 63671.02527305335 0.9049136307075761 0.7268817772065739 0.7823119229404747 0.9682878510847875 0.8847008742905647 0.8557384929574335 0.8642746032524485 0.7948938025556231 0.7833388420282524 1.0 15.958349375190084 -11.961226706101437 2.2501611007911295 2.5469315794626297 0.8403857272978278 0.3375915364420753 0.06698701471628916 2569967.9126674277 406174.555641604 20201012.087501608 0.018765038468621778 1.0933854590338863e-12 11.961226706101437 -1.706545852164802 ACQSIYPLHDVFVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ACQSIYPLHDVFVR 14 0 D6RAT0;P61247;D6RG13;D6R9B6;D6RB09;H0Y9Y4 D6RAT0 RPS3A 40S ribosomal protein S3a 0 ; 103.3 0.0010479 12454600.0 67452.0 74756.0 94520.0 92906.0 112663.0 100042.0 97087.0 85846.0 90793.0 75649.0 False True 78870.29136227346 82177.28163480731 96773.71526909628 87700.77802531605 90587.49390811268 94795.62140612434 87890.21651098966 83592.63346135548 92120.67586151944 89363.56486284571 0.8825777203866338 0.9195837449069111 1.082921383201572 0.9813930113454885 1.013696063346907 1.0607860323344944 0.9835128740206668 0.9354218756788921 1.0308527418630324 1.0 16.447399118049347 -5.0719730654304955 6.797549187284259 1.0084919552836074 0.8912039391503174 0.559585537952745 0.03957407860052412 0.1571153600945447 12.441266329484503 0.010246171311861653 0.028110184202858622 8.47279960084114e-06 5.0719730654304955 -0.11728801613328999 ACRPPGS(ph)PGRAPPPTPAPSGCDPR ddPTM_PC-9_Lapatinib_30min_R1 1 ACRPPGSPGRAPPPTPAPSGCDPR 24 2 O95685 O95685 PPP1R3D Protein phosphatase 1 regulatory subunit 3D 1 ACRPPGS(0.998)PGRAPPPT(0.001)PAPS(0.001)GCDPR 58.479 0.015658000000000002 4760400.0 10398.0 6302.5 8780.4 5854.3 6553.5 8439.0 6655.9 5872.5 10074.0 5945.9 True False 10249.722613240338 6287.906948474442 8058.50940532415 6284.844751372303 6168.036014676734 8078.083642269828 7000.509934431176 6145.357788615253 8939.360036077087 6973.640892586264 1.4697806742725887 0.9016677292860275 1.1555670172077857 0.9012286190494515 0.8844785829499803 1.1583739063561052 1.0038529431410035 0.8812265907108057 1.2818784582929406 1.0 12.767696359154675 -4.752561743275212 24.992258064055143 1.0152984109393988 1.4697815451077976 0.5146730780243618 0.13137307116330513 269.9515424190499 759909.3577934572 0.03101329614309388 0.36526218016647494 1.7678208702860057e-05 4.752561743275212 0.4544831341683988 ACS(ph)TLSLSGPELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ACSTLSLSGPELK 13 0 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 ACS(0.984)T(0.016)LSLSGPELK 147.73 0.00011151 5242400.0 14832.0 17502.0 25907.0 25095.0 40237.0 35473.0 44903.0 41449.0 40066.0 30510.0 True False 17342.764654646828 19239.482893311575 26524.721132844614 23689.008509087726 32352.848693721306 33612.733433352456 40649.46277043238 40361.00766884568 40651.88945257492 36041.22148297287 0.4811924774203381 0.5338188358127922 0.7359551103276513 0.6572754067250257 0.8976623810878863 0.9326191524677454 1.1278602971221885 1.1198568197227619 1.1279276278630093 1.0 15.137360286304816 -6.250095393301425 0.7585473716856002 1.1191517315393795 0.49014997246494574 0.9201605568309023 0.0658856179648151 0.18214033898272336 0.22513386012759395 0.03769842664373967 0.06715397433295248 5.622178198114778e-07 6.250095393301425 -0.6290017590744338 down ACS(ph)VEELYAIPPDADVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ACSVEELYAIPPDADVAK 18 0 Q9H792;H0YN99 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 ACS(1)VEELYAIPPDADVAK 195.46 7.1959e-54 0.0 7968.2 10023.0 10379.0 13832.0 15485.0 12788.0 11913.0 11428.0 11171.0 10831.0 True False 9317.058880876275 11018.017200300646 10626.474722576697 13057.03788394905 12450.825410002604 12117.37476801261 10784.51439734898 11128.027108966879 11334.354741544323 12794.574561851174 0.7282038832816214 0.8611476018243246 0.8305453746200384 1.0205136419995118 0.9731332096908086 0.9470713316363226 0.8428974597955393 0.8697457703788494 0.8858719519552685 1.0 13.643244556023182 -4.751525851964348 1.364198609404696 0.92296765761545 0.6444756926910167 0.501788911293832 0.05995229068244639 1.2882242177659629 2.0381482466115344 0.018854005919573265 0.5093267357760193 1.7720425587739895e-05 4.751525851964348 -0.2784919649244333 ACSMPQELPQS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 ACSMPQELPQSPR 13 0 Q8N5J2;Q8N5J2-3 Q8N5J2 FAM63A Protein FAM63A 1 ACSMPQELPQS(1)PR;ACSMPQELPQS(1)PR;ACSMPQELPQS(1)PR;ACSMPQELPQS(1)PR 123.1 0.00015123 18791300.0 62063.0 61138.0 79133.0 104460.0 78261.0 70050.0 53092.0 81291.0 57663.0 61984.0 True False 81797.74300940555 80899.66288124754 78083.64471541625 80378.36089091182 67395.81103319267 65669.76242628734 57817.08514716771 68729.34383134477 60710.948458652354 59813.95902646122 1.367536012341515 1.3525214548239177 1.3054418397697545 1.3438060646571326 1.1267572340994398 1.0979002810570617 0.9666152531650662 1.149051909453769 1.0149963227111303 1.0 15.868194590865018 -6.38897524239414 2.0655391155878213 1.0476199750103694 1.347502106339109 0.8859893447018843 0.05038024186535867 0.1003572785587276 0.8439904312665895 0.017123429866405134 0.020274697601967828 4.083426638528962e-07 6.38897524239414 0.29988213132873964 ACSMPQELPQS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ACSMPQELPQSPR 13 0 Q8N5J2;Q8N5J2-3 Q8N5J2 FAM63A Protein FAM63A 1 ACSMPQELPQS(1)PR;ACSMPQELPQS(1)PR 100.11 0.0020570999999999996 7116000.0 22053.5 23525.3 24841.7 31009.8 51392.0 62333.0 77716.0 56973.0 61311.0 56947.0 True False 25786.721973520336 25860.73631070867 25434.020340671872 29272.42144112805 41322.106520558824 59064.14774902482 70354.17786488475 55477.51911788328 62207.55738598369 67271.04030779605 0.38332574991458707 0.3844259906251467 0.37808275632871874 0.43514150081808184 0.6142629329276181 0.8780025918846964 1.0458315724416023 0.8246865049811632 0.9247301231162088 1.0 16.037697948337023 -6.577137201326426 1.9664124554330773 0.9410458544610191 0.38660085421450446 0.9558519801929586 0.055056617852329764 0.06451160216381216 0.5068501514313011 0.021485290945944025 0.022416134310633117 2.647663562609293e-07 6.577137201326426 -0.5544450002465147 down ACSTLS(ph)LSGPELK ddPTM_PC-9_AZD4547_30min_R2 1 ACSTLSLSGPELK 13 0 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 ACS(0.034)T(0.09)LS(0.876)LSGPELK 163.71 8.234e-13 0.0 27747.0 31404.0 45335.0 58008.0 47869.0 45587.0 41247.0 44947.0 41753.0 49449.0 True False 36569.96882654684 41554.72886130882 44733.8282786372 44635.15181466603 41223.21562908592 42736.4376834713 44917.90309397318 38001.47392930899 43959.978339561065 47717.80556110421 0.7663799371435429 0.8708432496564963 0.9374661670338983 0.9353982499783915 0.8638958800462492 0.8956077753564315 0.9413237378750442 0.7963793280612382 0.9212489514688365 1.0 15.542240077676723 ACTGLSGPGSGSKS(ph)PPATR ddPTM_PC-9_AZD4547_30min_R2 2 ACTGLSGPGSGSKSPPATR 19 1 I3L2J0;I3L2I4 I3L2J0 CIC 1 ACTGLS(0.004)GPGS(0.013)GS(0.031)KS(0.737)PPAT(0.215)R;ACT(0.001)GLS(0.071)GPGS(0.255)GS(0.255)KS(0.414)PPAT(0.004)R 54.626000000000005 0.015449000000000001 45730000.0 31435.0 23365.1 53838.0 74844.0 64063.0 51311.0 37462.0 48322.0 40155.0 54249.0 True False 41430.67611138139 30917.411645566357 53124.0729428757 57589.87212827304 55168.958257873186 48102.51505860431 40796.04542648979 40854.94522909359 42277.51132194276 52349.759022110506 0.7914205697467047 0.590593198958338 1.0147911649495494 1.100098132332363 1.0538531463835767 0.9188679366850128 0.7792976737344508 0.7804227945316433 0.8075970570196203 1.0 15.675895275666253 -5.263505864700173 24.98329316796246 0.928475836976404 0.6910068810506427 0.40402613077465 0.11695442921422007 191.73209000601503 2318027.012124425 0.03479226882742496 0.0787009857383311 5.451225343202065e-06 5.263505864700173 -0.23746895592576134 ACTLTVFPPEENPGS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 4 ACTLTVFPPEENPGSPSR 18 0 Q9P2J3 Q9P2J3 KLHL9 Kelch-like protein 9 1 ACTLT(0.027)VFPPEENPGS(0.487)PS(0.487)R;ACTLTVFPPEENPGS(0.991)PS(0.009)R;ACTLTVFPPEENPGS(0.992)PS(0.008)R;ACTLTVFPPEENPGS(0.994)PS(0.006)R 180.03 6.0571000000000006e-33 4524000.0 35969.4 40385.7 48360.9 48791.7 49808.9 52829.4 45373.9 62278.3 47920.4 41619.0 True False 47406.920990002254 53439.58773959238 47719.602867549285 37543.5273892505 42893.79399919737 49525.96926657118 49412.089199108545 52654.619747962795 50453.37451256444 40161.93147783767 1.180394449309853 1.3306030306107575 1.1881799781935816 0.9348038305868812 1.0680211937233945 1.2331570580439044 1.2303215353667771 1.3110579548948957 1.2562487075703976 1.0 15.29354103296392 -6.799912476364074 24.952449411986215 1.2271085450556125 1.1421996291045142 0.05522488014390914 0.12128734457253627 420.71019476963914 272856.62552651187 0.045750649867720795 0.040349018946612684 1.585212629154877e-07 6.799912476364074 -0.08490891595109828 ACTLTVFPPEENPGS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ACTLTVFPPEENPGSPSR 18 0 Q9P2J3 Q9P2J3 KLHL9 Kelch-like protein 9 1 ACTLT(0.001)VFPPEENPGS(0.904)PS(0.094)R 119.23 0.00062989 0.0 3280.2 4424.8 1422.1 3769.5 5671.9 3303.2 4272.2 3798.8 3460.1 3053.9 True False 3835.4730730968545 4864.064901515545 1456.008257344283 3558.3071358838874 4560.5319110748305 3129.974377048737 3867.5062879505 3699.085525161306 3510.6974166339187 3607.547895340901 1.0631800836380623 1.3483022381483607 0.40360053409816066 0.9863506290462263 1.2641639261296282 0.8676182459257316 1.0720595817855478 1.0253739194810483 0.973153376887369 1.0 11.81680283333895 ACTLTVFPPEENPGS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 3 ACTLTVFPPEENPGSPSR 18 0 Q9P2J3 Q9P2J3 KLHL9 Kelch-like protein 9 1 ACTLTVFPPEENPGS(0.948)PS(0.051)R;ACTLTVFPPEENPGS(0.996)PS(0.004)R;ACTLTVFPPEENPGS(0.844)PS(0.156)R 166.6 1.2555e-07 9842100.0 69988.7 77161.4 84617.9 75874.2 91487.4 89715.0 95296.3 88876.8 95647.8 76596.1 True False 68990.64830364418 76982.73751908247 77660.9428965399 81454.2417769115 86106.29100314883 85878.09858587962 100230.276125623 93006.34058871001 84874.9375480142 89835.63382711224 0.7679652868750944 0.8569287513152627 0.8644781540251343 0.9067030342733414 0.9584870427792551 0.955946932496198 1.115707340792131 1.035294533210505 0.9447803052333905 1.0 16.455000191425952 -5.9230185235451875 0.7982960629923782 1.0246139015750768 0.7869354617269946 0.7530688600646933 0.04647694745759001 0.4071639119233917 0.5004715017720429 0.023869404680524394 0.06483348337098783 1.1939371795230884e-06 5.9230185235451875 -0.23767843984808223 ACTLTVFPPEENPGSPS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 ACTLTVFPPEENPGSPSR 18 0 Q9P2J3 Q9P2J3 KLHL9 Kelch-like protein 9 1 ACTLTVFPPEENPGS(0.477)PS(0.523)R 117.27 0.0008176 0.0 6187.5 7243.5 10505.0 10895.0 8395.6 11994.0 9648.2 11777.0 8454.8 9629.9 True False 8154.996292004849 9584.819720637195 10365.696836154932 8383.326076072037 7230.015858604812 11244.013283952767 10506.871108959982 9957.135258537213 8901.703467183706 9292.760132113432 0.8775644884906952 1.0314287234762984 1.1154594209672648 0.9021352059977723 0.7780267386456801 1.2099756287796881 1.130651276863468 1.0714938421931144 0.9579181363373049 1.0 13.181891453657887 -6.774919525027896 24.99927780115448 1.0820163098104518 0.9534925759607088 0.27735349047165914 0.10605423969397329 357.46274681560004 662919.8088433712 0.0397216809750117 0.03522324960258627 1.6791151301217545e-07 6.774919525027896 -0.12852373384974303 ACY(ph)Y(ph)S(ph)LAS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 ACYYSLASK 9 0 P43403-2;P43403-3;P43403 P43403-2 ZAP70 Tyrosine-protein kinase ZAP-70 4 ACY(1)Y(1)S(1)LAS(1)K 47.062 0.041957 0.0 3657.0 2060.9 2310.5 3735.8 3489.2 2279.5 1164.7 2793.2 2315.9 2337.2 True False 4819.849929674623 2727.0456219039393 2279.8612603461193 2874.56902753464 3004.7848079760743 2136.9625046498522 1268.3560436771304 2361.5751213506096 2438.3137459964432 2255.3753393883144 2.1370500268845833 1.209131612941883 1.010856694462415 1.2745413046478813 1.3322770518502738 0.9474975039983469 0.562370272267464 1.0470874094025955 1.081112178276164 1.0 11.139151831319442 -2.6341279368673094 1.1884691809747983 1.0151815966077546 199.9999206580408 0.7349983141796961 0.19730196551607132 151.9013383206921 1.6171617991813305 0.06553476581634742 80925.64422392596 0.00232205265249636 2.6341279368673094 198.98473906143303 up ADAASSLT(ph)VDVTPPTAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADAASSLTVDVTPPTAK 17 0 Q9H8Y8-2;Q9H8Y8;Q9H8Y8-3 Q9H8Y8-2 GORASP2 Golgi reassembly-stacking protein 2 1 ADAASSLT(0.993)VDVT(0.006)PPT(0.001)AK 137.01 0.00013595 41531000.0 80899.0 79046.0 82806.0 89262.0 106670.0 82846.0 101290.0 87782.0 75186.0 69495.0 True False 94593.6028719169 86893.16448318529 84780.40908350369 84260.93953130867 85768.77923700195 78501.40991795219 91695.07792390487 85477.81551271725 76285.45301206269 82093.89337788276 1.1522611363612305 1.0584607564317996 1.0327249152778606 1.0263971662721718 1.0447644240991651 0.956239333863797 1.1169536996110943 1.0412201443444533 0.9292463772051411 1.0 16.32498728948059 ADAASSLTVDVT(ph)PPTAK ddPTM_PC-9_AZD4547_30min_R2 3 ADAASSLTVDVTPPTAK 17 0 Q9H8Y8-2;Q9H8Y8;Q9H8Y8-3 Q9H8Y8-2 GORASP2 Golgi reassembly-stacking protein 2 1 ADAAS(0.002)S(0.002)LT(0.007)VDVT(0.838)PPT(0.152)AK;ADAASSLTVDVT(0.996)PPT(0.004)AK;ADAASSLT(0.034)VDVT(0.938)PPT(0.028)AK 191.15 1.9666e-08 88037000.0 115809.0 118270.0 160399.0 190864.0 192823.0 164628.0 130324.0 186652.0 128939.0 157375.0 True False 152633.85302315807 156498.46460409474 158272.00445715536 146863.2536194045 166052.85481725584 154333.7851351156 141922.58352895905 157809.22223626432 135754.45230581443 151865.34915122212 1.0050604293621364 1.030508048602049 1.042186419362548 0.9670622985442406 1.0934216116140245 1.0162541092993866 0.9345290701411918 1.0391390999873413 0.893913279523922 1.0 17.21243320464287 -7.026796965699703 21.61086541647461 0.9709046750410347 1.0282074117774676 0.2800331194581911 0.046348073755600135 182.35121423429436 147059.02128118795 0.01657830223967442 0.01290676761893836 9.401627374481793e-08 7.026796965699703 0.057302736736432824 ADAASSLTVDVT(ph)PPTAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ADAASSLTVDVTPPTAK 17 0 Q9H8Y8-2;Q9H8Y8;Q9H8Y8-3 Q9H8Y8-2 GORASP2 Golgi reassembly-stacking protein 2 1 ADAAS(0.007)S(0.005)LT(0.189)VDVT(0.795)PPT(0.006)AK;ADAASSLT(0.001)VDVT(0.994)PPT(0.004)AK;ADAASSLT(0.005)VDVT(0.992)PPT(0.004)AK;ADAASSLTVDVT(0.984)PPT(0.015)AK;ADAASSLT(0.001)VDVT(0.997)PPT(0.002)AK 205.98 6.7241e-17 71937700.0 232386.0 250443.0 229413.0 285775.0 327625.0 266901.0 306579.0 264811.0 269507.0 209499.0 True False 271724.35996728414 275305.3259198733 234883.07597364706 269763.95324505074 263429.2331257407 252904.24170764236 277537.61768025253 257859.9918404469 273448.0300178483 247479.51030682825 1.097967098893952 1.112436846099082 0.9491011020768387 1.0900456078589857 1.0644486600088137 1.021919921346573 1.121456953491454 1.0419448119997845 1.1049319989312407 1.0 17.91694955881129 -10.558746108577235 13.800888694031373 0.9999960566276108 1.0651209677280389 0.14065497857273146 0.049560151032238466 0.0 0.0 0.046628228619995715 0.011309006572687692 2.762192180095752e-11 10.558746108577235 0.06512491110042806 ADAASSLTVDVT(ph)PPTAK ddPTM_PC-9_Lapatinib_30min_R1 3 ADAASSLTVDVTPPTAK 17 0 Q9H8Y8-2;Q9H8Y8;Q9H8Y8-3 Q9H8Y8-2 GORASP2 Golgi reassembly-stacking protein 2 1 ADAASSLT(0.001)VDVT(0.994)PPT(0.004)AK;ADAAS(0.002)S(0.001)LT(0.024)VDVT(0.921)PPT(0.052)AK;ADAASSLTVDVT(0.9)PPT(0.1)AK 185.99 7.2602e-08 24968600.0 224606.0 185645.0 222701.0 183902.0 203932.0 230529.0 164019.0 162653.0 238569.0 156455.0 True False 221403.07725230433 185215.15040849507 204391.3834307201 197426.76655908834 191937.1207057382 220669.81205934612 172511.1012688693 170210.45217396965 211698.8469770571 183498.0382868171 1.2065691781742085 1.009357659284586 1.1138614087592893 1.0759066876262726 1.0459900416250247 1.2025731398524686 0.9401250437305786 0.9275873124481132 1.153684524115515 1.0 17.485405114240947 -7.277241575608489 24.996182756654033 0.999314833663238 1.1003586487182022 0.27569719848504315 0.08137848463690639 1139.6380355785845 1802691.4587070548 0.032855206638313726 0.022237369330387047 5.28151386690636e-08 7.277241575608489 0.10104381505496418 ADAASSLTVDVTPPT(ph)AK ddPTM_PC-9_AZD4547_30min_R2 1 ADAASSLTVDVTPPTAK 17 0 Q9H8Y8-2;Q9H8Y8;Q9H8Y8-3 Q9H8Y8-2 GORASP2 Golgi reassembly-stacking protein 2 1 ADAASSLTVDVT(0.228)PPT(0.772)AK 172.57 2.1161e-05 58309000.0 105270.0 98329.0 128740.0 193300.0 167640.0 161860.0 140270.0 146410.0 112690.0 153910.0 True False 138743.67024797562 130111.92632160343 127032.8234827782 148737.6714552296 144366.07967703452 151738.8686126891 152753.75826100385 123785.69866709951 118646.56333880547 148521.65774655784 0.9341645680034915 0.8760468223673521 0.8553151466943031 1.0014544256504352 0.9720203899379137 1.0216615604413817 1.0284948375789598 0.8334521748897485 0.7988502494448844 1.0 17.1803137976871 -4.2727405051033935 18.37200871720498 0.9318970231260092 90.23407651333574 6.971988772819238e-05 0.08053061718488781 372665.4200522064 27170952.12186832 0.021051843091500853 10362228.987631869 5.3365366315449784e-05 4.2727405051033935 89.30217949020972 ADADPSPT(ph)SPPTAR ddPTM_PC-9_Lapatinib_30min_R1 1 ADADPSPTSPPTAR 14 0 Q9NWZ5-3;Q9NWZ5-2;Q9NWZ5 Q9NWZ5-3 UCKL1 Uridine-cytidine kinase-like 1 1 ADADPS(0.018)PT(0.434)S(0.434)PPT(0.115)AR 84.17299999999999 0.01807 3761300.0 34252.0 27961.0 39715.0 28535.0 32945.0 27504.0 30369.0 29498.0 34249.0 26393.0 True False 33763.56019895248 27896.258022418704 36449.786004333386 30633.559089969523 31007.2398723621 26327.718034955502 31941.35822334178 30868.58476774336 30391.51696204133 30954.994883538115 1.0907306018295602 0.9011876153548954 1.1775090301732662 0.989616028211992 1.0016877724910163 0.8505159872908459 1.0318644323319923 0.9972085243069865 0.9817968659462953 1.0 14.91788460037164 -4.394891266437026 10.620395389992483 0.9951144469097953 3.2775585267340217 0.11790530869128424 0.08039186725390084 92061.1818571556 167506.45196722395 0.02041268644047428 4815250.221799979 4.028178745202247e-05 4.394891266437026 2.2824440798242263 ADADPSPTS(ph)PPTAR ddPTM_PC-9_Lapatinib_30min_R1 1 ADADPSPTSPPTAR 14 0 Q9NWZ5-3;Q9NWZ5-2;Q9NWZ5 Q9NWZ5-3 UCKL1 Uridine-cytidine kinase-like 1 1 ADADPSPT(0.022)S(0.978)PPTAR 164.93 0.00050187 17074000.0 73549.0 70452.0 82324.0 69250.0 74303.0 71899.0 71906.0 70476.0 87751.0 55860.0 True False 72500.17777276537 70288.87272255814 75555.63849982993 74342.8760112278 69932.64362531863 68824.0473747552 75628.9408412398 73750.57224528705 77867.55832100463 65515.326571228674 1.1066140026630673 1.0728615180776002 1.153251345205238 1.1347402188463758 1.0674241782079406 1.050503004055536 1.1543702031159921 1.1256995287218017 1.1885395738102067 1.0 15.999544827905305 -7.297597873017724 24.995240530162917 1.1276272752880288 1.0992935936363437 0.015726733674950033 0.05388344831306422 1975.9822122591606 1365927.405488002 0.022027805432030603 0.014851504972129392 5.039670318142074e-08 7.297597873017724 -0.02833368165168504 ADAGKEGNNPAENGDAK ddPTM_PC-9_Lapatinib_30min_R1 1 ADAGKEGNNPAENGDAK 17 1 P05204 P05204 HMGN2 Non-histone chromosomal protein HMG-17 0 103.39 0.0058632 0.0 18821.0 7141.4 12969.0 6479.7 9289.4 10668.0 5319.1 6383.3 10654.0 6029.6 False True 18552.6090886513 7124.864527066307 11902.73888178773 6956.238753645544 8743.015755663091 10211.754508322607 5594.496971443813 6679.891421382332 9454.034328406324 7071.80832606302 2.623460398421151 1.0075024942075634 1.6831252111175588 0.9836577057679086 1.2363196727831078 1.4440089489823094 0.7910985017545508 0.9445803836005727 1.3368623543660896 1.0 12.787863457187557 -4.757602234789949 24.999987764545093 1.1676329565958135 2.6234624825318216 0.7467882185523875 0.25585013696891257 55.71969183731957 362976.6763400575 0.06323943733159296 0.46321303109804457 1.74742186337121e-05 4.757602234789949 1.4558295259360081 ADAGSHTEGS(ph)PSQPR ddPTM_PC-9_AZD4547_30min_R2 1 ADAGSHTEGSPSQPR 15 0 Q86V15-2;Q86V15 Q86V15-2 CASZ1 Zinc finger protein castor homolog 1 1 ADAGSHT(0.014)EGS(0.981)PS(0.006)QPR 139.49 2.1578e-06 0.0 1209.4 3527.4 3780.5 5120.9 3378.6 4693.6 2932.8 4285.1 4200.2 4204.9 True False 1593.964042917278 4667.563067933406 3730.3680998651816 3940.3556221163203 2909.539708881108 4400.108450021738 3193.813518413571 3622.9362568020574 4422.213997121748 4057.6877308719477 0.39282570484416124 1.1503012004648283 0.919333459665604 0.9710839974542806 0.7170437702104502 1.0843881397142918 0.7871018496850322 0.8928573357771749 1.0898359584145398 1.0 11.986442127958476 -4.747769631859438 24.999778296256917 0.943988918007493 0.3928243422983285 0.6307423729325436 0.12913540890018296 451.0002109273051 824759.5571155206 0.030860441992722205 0.607794010697953 1.7874354547098842e-05 4.747769631859438 -0.5511645757091644 ADAGSHTEGS(ph)PSQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ADAGSHTEGSPSQPR 15 0 Q86V15-2;Q86V15 Q86V15-2 CASZ1 Zinc finger protein castor homolog 1 1 ADAGS(0.017)HT(0.093)EGS(0.877)PS(0.014)QPR;ADAGS(0.013)HT(0.175)EGS(0.794)PS(0.017)QPR 89.23200000000001 0.004599 4040700.0 4918.0 6430.5 7537.700000000001 7802.299999999999 9032.099999999999 7152.799999999999 5588.5 5067.5 6371.5 3987.6 True False 5750.520265072349 7068.877542306028 7717.427354886437 7365.162426397898 7262.324842472359 6777.694576215246 5059.116822763768 4934.4834944600725 6464.671133806248 4710.520314175766 1.2207823937765057 1.5006574796064587 1.6383386208232098 1.5635560267585078 1.5417245565457456 1.4388420225720202 1.0740038223673385 1.047545316726544 1.3723900339314041 1.0 12.201670710364622 -7.1801588693301355 4.610761880340457 1.127667181753665 1.503322935483786 0.6216600294888792 0.13786902440233553 0.1508698527482426 5.796736845291907 0.05533094179345385 0.04202319615131613 6.604518038380546e-08 7.1801588693301355 0.37565575373012106 ADAGSHTEGS(ph)PSQPR ddPTM_PC-9_Lapatinib_30min_R1 1 ADAGSHTEGSPSQPR 15 0 Q86V15-2;Q86V15 Q86V15-2 CASZ1 Zinc finger protein castor homolog 1 1 ADAGSHT(0.035)EGS(0.929)PS(0.036)QPR 142.74 9.344799999999999e-05 1243900.0 6747.8 7671.9 8190.3 6692.9 6312.3 6428.5 5923.3 5045.1 7282.8 4929.0 True False 6651.575134605032 7654.136186910127 7516.925149472285 7185.118192859892 5941.022924459286 6153.568040565421 6229.979491070508 5279.513764043052 6462.534372716121 5780.971082520336 1.1505982368113037 1.324022569504559 1.3002876233373448 1.2428912184987766 1.0276859786451609 1.0644523130675554 1.077670066523567 0.9132572518839408 1.1178977165716324 1.0 12.497096140409223 -6.236354958952178 5.001393930510818 1.0322143935693762 1.2651023311960838 0.72812514867331 0.06609418028852719 0.09624237023701984 6.828103484842775 0.01953270650093529 0.02457080140392026 5.802899392213091e-07 6.236354958952178 0.23288793762670768 ADALQAGASQFETS(ph)AAK ddPTM_PC-9_AZD4547_30min_R2 2 ADALQAGASQFETSAAK 17 0 Q15836;K7ENK9;K7EKX0;J3QRU4;F8WCA0;L7N2F9;P63027 Q15836 VAMP3;VAMP2 Vesicle-associated membrane protein 3;Vesicle-associated membrane protein 2 1 ADALQAGASQFET(0.048)S(0.952)AAK;ADALQAGAS(0.003)QFET(0.24)S(0.757)AAK 132.5 1.7400999999999998e-05 0.0 41507.0 60439.0 49893.0 43229.0 47037.0 44802.0 54970.0 58009.0 49532.0 40119.0 True False 54705.362600766915 79974.72480093746 49231.386220492896 33263.2219313922 40506.724467720545 42000.523857566426 59862.2235089996 49045.04196420866 52150.160398417866 38714.44602127323 1.4130477954070897 2.0657592454504474 1.2716541570410358 0.8591940567382618 1.0462948235256284 1.0848798878456771 1.5462502931362072 1.2668408566987854 1.3470465358011796 1.0 15.240584377815622 -5.414367119371521 6.840620152201033 1.174606019961991 1.734060428004005 0.4851779474808625 0.23337256544689333 0.2036260915677866 11.203375724937358 0.06271949546877693 0.13156864159455645 3.851526414029654e-06 5.414367119371521 0.5594544080420141 ADAPDAGAQS(ph)DSELPSYHQNDVSLDR ddPTM_PC-9_AZD4547_30min_R2 3 ADAPDAGAQSDSELPSYHQNDVSLDR 26 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 ADAPDAGAQS(0.999)DS(0.001)ELPSYHQNDVSLDR;ADAPDAGAQS(0.951)DS(0.049)ELPSYHQNDVSLDR;ADAPDAGAQS(0.499)DS(0.499)ELPS(0.002)YHQNDVSLDR 201.89 1.6568999999999998e-32 136663000.0 40901.6 37497.6 186794.0 344021.0 246669.0 168334.0 121992.0 280850.0 131598.8 187813.0 True False 53907.45799386914 49617.96589446608 184316.98951096841 264712.2735214663 212423.26716687198 157808.04836926024 132849.05167018133 237451.085790963 138554.84390372504 181237.72403582843 0.29744060338791445 0.27377283707589056 1.0169902016344636 1.460580433404339 1.1720698231946378 0.8707240681198555 0.73300993144186 1.3101636927642166 0.7644922967380371 1.0 17.467523753302757 -5.2701075044669885 6.801183044891912 1.0558182770773903 0.28224300534566854 0.6600106288490581 0.2167262451459728 0.07756245586673297 21.8258430561959 0.058836483823546955 0.13516602075680992 5.3689887694709766e-06 5.2701075044669885 -0.7735752717317217 ADAPDAGAQS(ph)DSELPSYHQNDVSLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ADAPDAGAQSDSELPSYHQNDVSLDR 26 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 ADAPDAGAQS(0.942)DS(0.044)ELPS(0.007)Y(0.007)HQNDVSLDR;ADAPDAGAQS(0.828)DS(0.172)ELPSYHQNDVSLDR;ADAPDAGAQS(0.923)DS(0.077)ELPSYHQNDVSLDR;ADAPDAGAQS(0.851)DS(0.149)ELPSYHQNDVSLDR 128.01 1.8932e-12 116934000.0 44224.3 54741.7 164483.0 155874.0 185463.0 163237.0 135830.0 126489.0 149206.0 111463.0 True False 51710.600520260115 60176.09420070817 168404.89852525134 147140.88513032623 149122.8565072853 154676.56435768472 122963.19907595993 123168.7977761734 151387.85547998015 131670.3595593775 0.392727723181624 0.4570208086473054 1.278988673599757 1.1174943671659998 1.1325468921502981 1.174725768770552 0.9338715219389141 0.9354329872595943 1.149748933522969 1.0 17.006571090118975 -5.248806030817971 24.08104407642006 1.08794638457693 0.42487400476111026 0.8682533486690065 0.10368724518156328 157.9608161903159 301094.3746789231 0.027936379703166356 0.0727268308035939 5.638894498457728e-06 5.248806030817971 -0.6630723798158197 ADAPDAGAQS(ph)DSELPSYHQNDVSLDR ddPTM_PC-9_Lapatinib_30min_R1 4 ADAPDAGAQSDSELPSYHQNDVSLDR 26 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 ADAPDAGAQS(0.985)DS(0.015)ELPSYHQNDVSLDR;ADAPDAGAQS(0.99)DS(0.01)ELPSYHQNDVSLDR;ADAPDAGAQS(0.905)DS(0.095)ELPSYHQNDVSLDR;ADAPDAGAQS(0.977)DS(0.023)ELPSYHQNDVSLDR 171.49 5.9812e-14 139402000.0 182888.0 122222.0 329702.0 157665.0 230545.0 271516.0 157219.0 188430.0 366911.0 131277.0 True False 180279.98358244795 121939.00246829708 302595.1742465241 169260.21005502206 216984.79636890962 259903.8936147097 165359.030541525 197185.14569753484 325585.6194358827 153968.05453439252 1.170892131667339 0.7919759903250517 1.9653114093153141 1.0993203139889884 1.4092845235012097 1.6880377842057739 1.0739827235044268 1.2806886876231116 2.1146309890091857 1.0 17.23227152441134 -5.23021340319076 24.99898034217145 1.4444673938377819 0.9814340310758937 0.21092478299423345 0.36517273739696743 1031.258815276895 825604.9899472969 0.08829079860545544 0.23354183979910442 5.88554381023112e-06 5.23021340319076 -0.4630333627618882 ADAPDAGAQSDS(ph)ELPSYHQNDVSLDR ddPTM_PC-9_AZD4547_30min_R2 1 ADAPDAGAQSDSELPSYHQNDVSLDR 26 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 ADAPDAGAQS(0.231)DS(0.769)ELPSYHQNDVSLDR 155.32 1.344e-10 71282000.0 12435.0 10356.0 47799.0 90450.0 64930.0 49409.0 26418.0 64161.0 37292.0 47324.0 True False 16389.071335932156 13703.374477382311 47165.15402868822 69598.14993856967 55915.590273382586 46319.44741927816 28769.150821552706 54246.39172310484 39263.178986873114 45667.201164304526 0.358880573323652 0.30007038154318655 1.0328015036216969 1.5240292412089098 1.224414653138162 1.014282597539248 0.6299740314289269 1.1878632878755482 0.8597675790467082 1.0 15.478870752578366 -5.272606908243087 7.556114008984242 1.0721969592408178 0.32774298397499624 0.6331215343417922 0.2220330567949993 0.08791848217535239 36.44565896444091 0.06252179228332891 0.14090404370412637 5.338178499533592e-06 5.272606908243087 -0.7444539752658216 ADATNVNNWHWTER ddPTM_PC-9_AZD4547_30min_R2 2 ADATNVNNWHWTER 14 0 O95433;O95433-2;G3V3W9 O95433 AHSA1 Activator of 90 kDa heat shock protein ATPase homolog 1 0 ; 157.35 1.6262e-05 53209000.0 84247.0 64288.0 175871.0 263560.0 211062.0 197524.0 139119.0 223031.0 137941.0 166774.0 False True 111035.7935535408 85067.83877964005 173538.8356279299 202800.31396140833 181759.68449531336 185172.79305481806 151500.3214907861 188566.6836925204 145232.2796478672 160935.29302205463 0.6899406057459654 0.5285841109319777 1.0783143483893745 1.2601357362528087 1.129396051557224 1.150604007223213 0.9413741302227874 1.1716925489220016 0.902426540012976 1.0 17.29612121743071 -5.268381644142023 24.613547249244277 1.091251184027096 0.6092623458337548 0.7465325441877305 0.10936205153026232 175.89994003094435 623649.237768635 0.028091362675921196 0.06062356546433894 5.390367260368942e-06 5.268381644142023 -0.48198883819334115 ADATNVNNWHWTER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ADATNVNNWHWTER 14 0 O95433;O95433-2;G3V3W9 O95433 AHSA1 Activator of 90 kDa heat shock protein ATPase homolog 1 0 ;; 147.56 1.6262e-05 36871400.0 95333.0 110573.0 158864.0 188009.0 200637.0 195795.0 180675.0 158101.0 153919.0 116813.0 False True 111470.99398742242 121549.95668850093 162651.92025507495 177475.46526340206 161323.62013475588 185527.16552260157 163560.15602627583 153951.0162718563 156169.77418886047 137990.2722088005 0.8078177700725864 0.8808588804330869 1.1787201927463233 1.2861447580511645 1.1690941510039812 1.344494525250812 1.1853020753432832 1.1156657190943484 1.1317448084496244 1.0 17.074207040492496 -5.224661108082113 3.9298654275349154 1.1920114221197622 0.8267030261097736 0.6891054336373009 0.0892691670545993 0.11430643142327984 3.87874846634786 0.023306954726458183 0.06586452164262907 5.961271364671551e-06 5.224661108082113 -0.36530839600998855 ADATNVNNWHWTER ddPTM_PC-9_Lapatinib_30min_R1 2 ADATNVNNWHWTER 14 0 O95433;O95433-2;G3V3W9 O95433 AHSA1 Activator of 90 kDa heat shock protein ATPase homolog 1 0 ; 148.57 2.2534e-05 32557000.0 148644.0 114129.0 193882.0 141203.0 154906.0 177815.0 134873.0 135183.0 191090.0 111156.0 False True 146524.30930202882 113864.74131256492 177941.7703661634 151587.53965939983 145794.73363691365 170210.26695701008 141856.06400134257 141464.09568980415 169567.4319330922 130369.16649393998 1.1239184328822092 0.8734023878096802 1.3649068652627672 1.1627560698291812 1.1183222042283343 1.3056021721587219 1.0881105388361638 1.0851039359554384 1.3006712897943877 1.0 16.992243173712616 -5.24952464049564 24.983852761276875 1.1798683670210126 0.9986604336511268 0.255928514699686 0.12241484767836243 965.7051388967766 2024965.5649496056 0.029430044335401733 0.07647657097071146 5.629571760780587e-06 5.24952464049564 -0.18120793336988583 ADCASESACS(ph)SDSLDEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADCASESACSSDSLDEAR 18 0 Q6NUJ5-2;Q6NUJ5 Q6NUJ5-2 PWWP2B PWWP domain-containing protein 2B 1 ADCAS(0.003)ES(0.003)ACS(0.331)S(0.331)DS(0.331)LDEAR 62.357 0.020972 1044700.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADDADEFGYS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 ADDADEFGYSR 11 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 1 ADDADEFGYS(1)R 91.09299999999999 0.00838 19904000.0 24751.0 20051.0 22652.0 24869.0 26358.0 22236.0 23802.0 30398.0 21616.0 21904.0 True False 32621.303147218106 26532.093631324118 22351.61967944612 19135.83627221987 22698.64667219802 20845.579404866916 25920.331889416208 25700.687576548713 22758.577630061387 21137.147627058723 1.5433162374973404 1.2552352899952808 1.057456761613033 0.9053178134462725 1.073874634018279 0.986205886085663 1.2262927972473585 1.2159014087429647 1.076709972017558 1.0 14.367493083519665 -4.870971944165054 2.431391171229314 1.0734125983142764 1.6016088949612781 0.7146706220624953 0.09287580263158149 0.260830597008355 2.254458860359508 0.027079699613768476 0.2707280234744359 1.3459473007181676e-05 4.870971944165054 0.5281962966470017 ADDADEFGYS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADDADEFGYSR 11 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 1 ADDADEFGYS(1)R 93.649 0.0069867 8705600.0 37810.0 46363.0 30586.0 52749.0 49947.0 40784.0 39022.0 43487.0 33780.0 33430.0 True False 44210.48621845986 50965.61223760741 31315.286238050932 49793.6445445654 40160.24389753955 38645.21524387128 35325.55366518525 42345.5123282852 34273.96859451856 39490.59436826563 1.119519392546472 1.2905759726564923 0.792980879092964 1.2608988378402133 1.0169571904395556 0.978592899450668 0.8945308175349376 1.0722936184093943 0.8679020699182206 1.0 15.269221461343564 -6.510315250404256 21.19137107076164 0.966796069490957 1.109583647910439 0.2214883891562196 0.13541204875428928 129.89604588012958 219102.7623767761 0.041535766687506005 0.044775788273146135 3.088053029206817e-07 6.510315250404256 0.1427875784194821 ADDADEFGYS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 2 ADDADEFGYSR 11 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 1 ADDADEFGYS(1)R;ADDADEFGYS(1)R 128.21 0.00032122 25313000.0 81066.0 78647.0 100674.0 77592.0 84156.0 78721.0 74959.0 70180.0 89728.0 65018.0 True False 79909.98397431645 78464.89770355742 92396.97233287827 83298.37451932418 79206.1095370618 75354.28633761377 78840.01024279611 73440.81900468584 79621.88776227161 76256.27466896072 1.0479135562446107 1.0289631645944501 1.2116638628622576 1.0923478085040768 1.0386831756587471 0.9881716182010909 1.0338822685090736 0.963079029542196 1.0441355561613979 1.0 16.218568432670992 -6.39973538321776 3.3059451523461894 1.0057899045526448 1.0987565720240973 0.4166626651955655 0.04974097327641738 0.2589674897565745 5.284823765784125 0.01688759236599641 0.019258668377183288 3.983498122243413e-07 6.39973538321776 0.09296666747145244 ADDADEFGYSR ddPTM_PC-9_AZD4547_30min_R2 1 ADDADEFGYSR 11 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 214.71 6.067e-08 17666000.0 29531.0 28318.0 44356.0 50843.0 37962.0 38640.0 32864.0 46059.0 31888.0 39218.0 False True 38921.243717041645 37471.239711327944 43767.81045830443 39121.93186651954 32691.631571818107 36223.83469167375 35788.83233399605 38941.63988052691 33573.534579357736 37844.989757030155 1.0284384793580652 0.9901241868976122 1.1565021087150391 1.033741378123961 0.8638298433082612 0.9571632843405578 0.9456689660577289 1.0289774189539327 0.8871328753133314 1.0 15.207814696110944 -6.021855180003634 24.21656101325591 0.9489862590447857 1.058796825391198 0.43246822079572933 0.05944761952044282 480.97359644373404 532941.2434959587 0.017339583209954528 0.022613064569234186 9.509218355350676e-07 6.021855180003634 0.10981056634641218 ADDADEFGYSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ADDADEFGYSR 11 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 ; 157.78 0.0026589 28117000.0 75585.0 51705.0 100389.0 79686.0 102960.0 85352.0 89886.0 71934.0 80549.0 69407.0 False True 88380.04762820121 56837.93069355936 102782.6544874027 75221.45176549755 82785.72710454417 80875.99086639137 81371.34736171493 70045.8087203732 81726.87674126327 81989.93967449045 1.0779377077124368 0.6932305465672072 1.253600806336262 0.9174473363943847 1.0097059155454082 0.9864135915635309 0.9924552656675757 0.8543219936307206 0.9967915218102176 1.0 16.323159278644404 -8.48619968536688 24.845730725783984 1.0000011345413584 0.9706033409023043 0.005179305058001571 0.1368017884781351 4084.1205992740674 2766513.5429915995 0.12334808853503881 0.031848339408236975 3.2643770403703047e-09 8.48619968536688 -0.02939779363905415 ADDADEFGYSR ddPTM_PC-9_Lapatinib_30min_R1 2 ADDADEFGYSR 11 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 ; 147.3 0.0011654999999999999 38140000.0 129780.0 108251.0 210000.0 132366.0 158512.0 154804.0 136206.0 104560.0 191465.0 106205.0 False True 127929.31340126255 108000.35146042178 192734.61062344207 142100.63720003158 149188.63580658264 148183.3937857492 143258.08021892345 109418.23931504638 169900.19548416726 124562.39274073268 1.02702999345507 0.8670381893290734 1.5472937407729856 1.140798872544167 1.1977020714198034 1.1896318826676835 1.1500909469289373 0.8784211422687767 1.3639766525503554 1.0 16.9265090372133 -7.54896768043565 24.975344383648423 1.0755706016067135 1.1667101195371454 0.032804271611948876 0.19597751721302964 867.4152458934265 830379.8296272092 0.09180462468775756 0.053005532531405365 2.825090206201583e-08 7.54896768043565 0.09113951793043196 ADDGRPFPQVIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADDGRPFPQVIK 12 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8;H3BU78 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 106.16 0.0022099 44223000.0 127280.0 152370.0 145180.0 163250.0 157050.0 169640.0 153510.0 133520.0 154800.0 105730.0 False True 148825.99010541075 167496.28662175132 148641.64179821577 154103.6317636413 126277.17989285791 160743.77976584752 138968.42148384487 130015.24147613387 157063.6571471724 124898.01204178044 1.1915801354438371 1.3410644723930518 1.1901041447200351 1.2338357452165938 1.0110423523043435 1.2870003063945972 1.11265519132008 1.0409712640793805 1.257535284826087 1.0 16.930390988690213 -1.5228787559707555 0.05276047151183047 0.7232404914111265 2.019198326432741 0.2951034035541734 0.09555996862952544 527.7986530684218 2.104365923437549 11.694591118168905 54.712436701866494 0.0299999992615321 1.5228787559707555 1.2959578350216145 ADDGRPFPQVIK ddPTM_PC-9_Lapatinib_30min_R1 1 ADDGRPFPQVIK 12 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8;H3BU78 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 134.38 7.4169e-05 71520000.0 246510.0 218700.0 241770.0 234510.0 247980.0 229000.0 213070.0 221980.0 233380.0 173370.0 False True 242994.72219560263 218193.61358688766 221892.60385918824 251756.64770242735 233394.3039474384 219206.2038250729 224101.7220404833 232294.00117783173 207094.28679964994 203336.773498996 1.1950357921696957 1.0730651904829454 1.0912566381421602 1.2381265000433896 1.1478214192701883 1.0780450582203975 1.1021209699758998 1.1424101857255973 1.018479260961975 1.0 17.633511624922114 -8.304873109690844 5.091283237083147 1.0040839549663827 1.1312545440438035 0.5001035320393623 0.049686152331643446 0.18405716379857562 11.363144649264603 0.047603930728576445 0.012975905692291918 4.955949704776257e-09 8.304873109690844 0.12717058907742085 ADDLGKGGNEESTK ddPTM_PC-9_AZD4547_30min_R2 1 ADDLGKGGNEESTK 14 1 P00441;H7BYH4 P00441 SOD1 Superoxide dismutase [Cu-Zn] 0 115.24 0.00020985 5809600.0 21260.0 15211.0 22706.0 44495.0 32013.0 24145.0 18750.0 24768.0 19951.0 29306.0 False True 28020.237764528974 20127.658282682714 22404.903604163148 34237.36519089723 27568.54753460337 22635.209333086514 20418.713676437023 20940.674712019158 21005.56912922624 28280.005860052173 0.9908144256826289 0.7117275145658538 0.7922524385262562 1.2106562268878565 0.9748423557983135 0.8003962037737977 0.7220194287611563 0.7404763215272022 0.74277103170259 1.0 14.787494798645394 -6.842746416994493 6.166099204594564 0.7778572096422804 0.9305310088657179 0.17227939188293906 0.14365385703856196 0.370454843632286 22.14249905627239 0.05383664007666068 0.04763855489881886 1.4363278552873614e-07 6.842746416994493 0.1526737992234375 ADDLGKGGNEESTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADDLGKGGNEESTK 14 1 P00441;H7BYH4 P00441 SOD1 Superoxide dismutase [Cu-Zn] 0 104.41 0.0013859000000000002 4511700.0 18001.0 13131.0 13990.0 26719.0 30220.0 30674.0 23384.0 33421.0 33459.0 23610.0 False True 21048.213764043798 14434.558900244223 14323.574657370455 25222.02105416677 24298.607936085155 29065.401441509144 21168.898234500848 32543.73416247656 33948.27457679091 27890.30610334283 0.7546784781082426 0.5175475251780814 0.5135682127079159 0.9043293021134591 0.8712205540538263 1.042132751566519 0.7590055898297804 1.1668475075852964 1.2172069553844729 1.0 14.767476147954802 -6.277823961066461 0.8046059383757264 1.0766108552390197 0.5672756325393987 0.6222318571781799 0.14190457393227152 0.45612102297611007 0.6378763581332719 0.08114130922240442 0.1357843753377613 5.27443614531754e-07 6.277823961066461 -0.509335222699621 ADDLGKGGNEESTK ddPTM_PC-9_Lapatinib_30min_R1 2 ADDLGKGGNEESTK 14 1 P00441;H7BYH4 P00441 SOD1 Superoxide dismutase [Cu-Zn] 0 ; 116.9 0.00017868 15929200.0 125578.0 58056.0 66263.0 53371.0 50412.0 49559.0 41680.0 38384.0 62712.0 36422.0 False True 123787.23469181529 57921.574898949984 60815.11192257687 57296.08138043681 47446.86527380538 47439.477097671595 43837.986458193736 40167.46076768122 55648.71417336375 42717.494170735605 2.897811238577238 1.355921643424258 1.4236582248834102 1.341279082322402 1.1107127464960178 1.110539792153138 1.0262302906387646 0.9403047053073321 1.302714853800739 1.0 15.382539399854782 -2.7125688526359735 1.1324592728851672 1.1205420438281892 199.99999999999991 0.9215128248707571 0.15121295540140883 44.71537393812031 0.6715098244789999 0.04650652673774888 22461.973376380505 0.0019383453081611806 2.7125688526359735 198.87945795617173 up ADDPLRLDQELQQPQT(ph)QEK ddPTM_PC-9_AZD4547_30min_R2 1 ADDPLRLDQELQQPQTQEK 19 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0;H7C3N7 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 ADDPLRLDQELQQPQT(1)QEK 88.62700000000001 0.00079651 3739000.0 15234.0 14901.0 13350.0 22457.0 23606.0 21103.0 19286.0 20434.0 16496.0 21088.0 True False 20078.095113115447 19717.45684506314 13172.970277264953 17279.885607191354 20328.714369220204 19783.42607397492 21002.41663806742 17276.3948266069 17367.94488274855 20349.71553868764 0.986652372360891 0.9689303424206355 0.6473294554030156 0.8491462976148186 0.998967987074438 0.9721721188860785 1.0320742124448328 0.8489747580875059 0.8534735952318189 1.0 14.312721007269817 -6.242138796242088 23.299560134029793 0.9485104540188702 0.8551739178201053 0.14807001606177972 0.10253879147557371 711.3256924532557 858705.9354844559 0.032499281809355476 0.04186979786942159 5.726130002607543e-07 6.242138796242088 -0.09333653619876492 ADDPLRLDQELQQPQT(ph)QEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADDPLRLDQELQQPQTQEK 19 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0;H7C3N7 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 ADDPLRLDQELQQPQT(1)QEK 80.752 0.01175 0.0 5492.7 1738.4 5725.9 5930.1 7602.7 4356.6 8699.3 5847.2 5080.5 5478.3 True False 6422.5056242299515 1910.9768633146418 5862.427171596678 5597.855722643598 6113.0055114386 4128.132226644021 7875.239326522118 5693.717195620507 5154.792701138296 6471.472423801064 0.9924334376530726 0.2952924370482315 0.9058876848544679 0.865004956531308 0.9446081372387404 0.6378969044913791 1.2169161530470591 0.8798178872987088 0.7965409359050615 1.0 12.659878283871564 -5.413749704707062 20.258390929295185 0.9031235279245825 0.6330027899514542 0.20053752234695277 0.2089332917394044 8.730480125816008 1608.9059735521414 0.051164984656604025 0.106508546198889 3.857005829778084e-06 5.413749704707062 -0.2701207379731283 ADDPLRLDQELQQPQT(ph)QEK ddPTM_PC-9_Lapatinib_30min_R1 1 ADDPLRLDQELQQPQTQEK 19 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0;H7C3N7 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 ADDPLRLDQELQQPQT(1)QEK 118.36 4.0721e-05 2389800.0 13711.0 9101.4 14041.0 11574.0 13189.0 13291.0 11799.0 8779.4 13285.0 9719.8 True False 13515.478625710544 9080.326267488352 12886.603179827389 12425.190569732162 12413.248950571675 12722.574912834254 12409.894487049613 9187.322974775441 11788.703402748073 11399.854479180603 1.1855834344546832 0.7965300157183257 1.1304182174747945 1.0899429104489111 1.0888953866246118 1.116029589331102 1.0886011316823063 0.8059158116056764 1.0341099901123842 1.0 13.476727787842584 -7.712923096393191 24.999992802582366 0.9400080595899339 1.0657623449268263 0.20336127408644278 0.11208336504364746 169.1385094510598 87155.20726886363 0.05128470243622519 0.029609155452612123 1.9367648902910217e-08 7.712923096393191 0.12575428533689237 ADEASELACPT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 5 ADEASELACPTPK 13 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 1 ADEASELACPT(1)PK;ADEASELACPT(1)PK;ADEASELACPT(1)PK;ADEASELACPT(1)PK;ADEAS(0.013)ELACPT(0.987)PK 153.14 0.00022989 302713300.0 1180669.0 1329668.0 967751.0 1019049.0 1052172.0 1325548.0 1247631.0 1232331.0 1291682.0 1190299.0 True False 1556097.182559202 1759457.1779250659 954917.9894227297 784122.9972001043 906096.0796107424 1242661.2740134236 1358667.742018493 1041902.5600992123 1359957.6734989316 1148626.9943088184 1.3547454397896832 1.5317915969612155 0.8313560399974299 0.6826611259227345 0.7888514583935772 1.0818666809769606 1.1828624512138213 0.9070852115278494 1.1839854715562215 1.0 20.13147894187017 -5.259262795772059 24.994397472272894 0.9506904328744655 1.4432685532186516 0.5941670292890893 0.1605663315877991 134.23627502974864 1541449.9645809692 0.04553942972949051 0.10901406527667366 5.504744981864404e-06 5.259262795772059 0.492578120344186 ADEASELACPT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 ADEASELACPTPK 13 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 1 ADEASELACPT(1)PK;ADEASELACPT(1)PK;ADEASELACPT(1)PK;ADEASELACPT(1)PK;ADEAS(0.001)ELACPT(0.999)PK;ADEASELACPT(1)PK 143.64 0.00021285 115494200.0 544579.0 652354.4 463298.3 651066.0 682762.7 526488.0 842310.0 553931.4 533573.1 566669.3 True False 636765.4687744684 717115.8335719649 474345.08854058775 614588.8828044528 548980.2501880517 498878.0424508462 762520.2990036955 539391.2876888337 541375.5971663692 669401.9583382887 0.9512453031287262 1.0712783621848376 0.7086102492411187 0.9181163501972672 0.82010553352851 0.7452593112951925 1.1391067646359476 0.8057808630076446 0.8087451648786181 1.0 19.352513246077933 -5.232757182739846 24.97093106977197 0.866626452716469 1.011261839405854 0.17828351600374848 0.12280267049250077 1192.4367613471634 1038140.466008199 0.030401225221697175 0.08040433054936233 5.851171360300957e-06 5.232757182739846 0.14463538668938491 ADEASELACPT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 5 ADEASELACPTPK 13 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 1 ADEASELACPT(1)PK;ADEASELACPT(1)PK;ADEAS(0.001)ELACPT(0.999)PK;ADEASELACPT(1)PK;ADEASELACPT(1)PK 134.02 0.00010946 274396900.0 649118.0 1181440.0 1006628.0 1045413.0 1296674.0 1320178.0 1483952.0 1397021.0 1281397.0 1104745.0 True False 639861.4582863378 1178704.4482674594 923866.9315364478 1122296.1594155352 1220406.1846791683 1263717.0644252286 1560783.7735271002 1461931.6957358976 1137072.5761513875 1295698.7012698206 0.49383506957231327 0.9097056646829208 0.7130260535346934 0.8661706292640827 0.9418904128584342 0.9753170727012005 1.2045885142876882 1.128296026154201 0.8775748366784847 1.0 20.30529884563319 -4.379220806829055 0.44722457205986216 1.0664642820267638 0.05320221764823697 0.6210124753902699 0.11725453443366687 4.903420097883268 0.582484411796554 0.08418243992793496 2.836280515638431 4.176179846051817e-05 4.379220806829055 -1.0132620643785268 ADEASELACPT(ph)PKEDGLAQQQTQLNLR ddPTM_PC-9_AZD4547_30min_R2 3 ADEASELACPTPKEDGLAQQQTQLNLR 27 1 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 1 ADEAS(0.006)ELACPT(0.993)PKEDGLAQQQT(0.001)QLNLR;ADEAS(0.001)ELACPT(0.958)PKEDGLAQQQT(0.041)QLNLR;ADEAS(0.003)ELACPT(0.996)PKEDGLAQQQTQLNLR 63.268 0.00056256 12344700.0 23647.4 14314.4 29746.5 91769.0 51187.0 27590.4 18011.4 21893.4 15729.1 36904.0 True False 31166.781303524123 18941.24986665133 29352.041973982192 70613.07486691643 44080.56860193492 25865.16792642742 19614.37970729481 18510.278090282638 16560.508114405915 35612.00219270336 0.8751763277693488 0.531878262956309 0.8242176841153911 1.982844842163481 1.2378009066551925 0.7263047942787954 0.5507800320003815 0.5197763942088957 0.4650260332118884 1.0 15.12007592932742 -6.901289734873641 5.08845598880154 0.5996845915284803 1.092086556627635 0.2504427459030121 0.37898979460358045 0.3206792569846403 13.433163971994492 0.1508820598681152 0.13261998001647074 1.2551922963199453e-07 6.901289734873641 0.4924019650991547 ADEFADQSPGNLSSS(ph)SLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADEFADQSPGNLSSSSLR 18 0 A0A087WV86;Q6PGQ7-2;Q6PGQ7;H3BLY2 A0A087WV86 BORA Protein aurora borealis 1 ADEFADQS(0.028)PGNLS(0.023)S(0.034)S(0.458)S(0.458)LR 79.027 0.004214 2687100.0 7543.7 9283.3 7463.9 8489.8 10136.0 9020.8 12882.0 9708.4 10510.0 9149.9 True False 8820.699415133444 10204.884672807644 7641.867682998377 8014.14403030297 8149.923561884813 8547.733367789187 11661.7237023965 9453.564786900077 10663.688867033461 10808.704439431454 0.8160736991710561 0.9441357870402115 0.7070105141482012 0.7414527869840172 0.7540148412378557 0.7908194192641652 1.0789196584794316 0.8746251541870582 0.986583445480389 1.0 13.399905987652488 -7.2381091713250605 23.930127312774008 0.9745841494872308 0.7912333788407138 0.6105126408566481 0.07524681456487081 336.0485566256602 344690.0645332028 0.029771255182171136 0.023042950655136125 5.779507460435466e-08 7.2381091713250605 -0.18335077064651706 ADEGISFR ddPTM_PC-9_AZD4547_30min_R2 4 ADEGISFR 8 0 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 ;;; 139.97 0.011986 235275000.0 267155.0 256723.0 349780.0 504420.0 377323.0 347700.0 305864.0 417639.0 298509.0 323710.0 False True 352104.7328307966 339703.68925811315 345141.688657808 388133.76221131353 324938.21451907424 325958.26403454883 333085.30346291926 353102.4889394763 314287.57632179855 312377.011429655 1.1271787613925872 1.0874797978999549 1.1048882473079533 1.2425170483414987 1.0402116757309714 1.0434771193396613 1.0662926248589442 1.1303728380120968 1.0061162147732943 1.0 18.252928760449457 ADEGISFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ADEGISFR 8 0 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 ;; 122.18 0.015388999999999998 132167000.0 179448.0 194353.0 208035.0 216333.0 242192.0 207169.0 224500.0 211873.0 185142.0 158213.0 False True 209825.00214044412 213647.08140577032 212995.34337713147 204212.56337104854 194736.21618981913 196304.69293981872 203233.7347607522 206311.55824800004 187849.35149574818 186895.76448658152 1.1226846296750017 1.1431349554265016 1.1396477815441548 1.0926548492526715 1.0419509330496386 1.0503431871721882 1.0874175523402174 1.1038856809556672 1.0051022398061629 1.0 17.511874348905415 -1.5228787693088552 0.11390676317357745 0.9670226186627342 1.5253664925294121 0.6493792875776125 0.029291773184831227 71.26794265461405 0.565504828172647 0.2629249043148967 6.273359591473777 0.029999998340168848 1.5228787693088552 0.5583438738666779 ADEGISFR ddPTM_PC-9_Lapatinib_30min_R1 4 ADEGISFR 8 0 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 ;;; 139.97 0.011986 289452000.0 497454.0 504226.0 563499.0 453995.0 492084.0 496359.0 487665.0 433939.0 513990.0 410165.0 False True 490360.2147381084 503058.49567655334 517170.28738904314 487383.30678292346 463140.5865943671 475130.8826393425 512913.9075368297 454101.3901122033 456099.033645351 481061.4737394923 1.0193296314633826 1.0457260103705022 1.0750607055868804 1.0131414245133556 0.9627471994258475 0.987671864358522 1.0662128138213502 0.9439570925983389 0.948109666941113 1.0 18.87586173889421 -5.987052104045544 7.224984293145675 0.9862974177086931 1.0464268672254298 0.3922909571580844 0.03455183774736247 0.16216816886744284 44.54026311709205 0.010367895485392003 0.015018234344396135 1.0302625083139609e-06 5.987052104045544 0.06012944951673671 ADEHVIDQGDDGDNFYVIER ddPTM_PC-9_AZD4547_30min_R2 3 ADEHVIDQGDDGDNFYVIER 20 0 P13861-2;P13861;H7C1L0 P13861-2 PRKAR2A cAMP-dependent protein kinase type II-alpha regulatory subunit 0 ;; 159.4 8.382e-06 11764600.0 43422.5 37740.7 58195.0 78524.0 71252.0 65457.0 50238.5 62167.0 50722.2 53435.1 False True 57229.951755891816 49939.643215386466 57423.29627606247 60421.504983706276 61359.88969904592 61363.96344236252 54709.629175129645 52560.51860554324 53403.27194057641 51564.35341337862 1.109874321454077 0.9684916014563926 1.113623898581917 1.1717688865275215 1.189967208686569 1.1900462117777926 1.0609970949608565 1.0193188729465608 1.035662592575449 1.0 15.654086450517386 -7.495403294139377 6.890475126622956 1.0240389657717273 1.1220768904074263 0.38698105554960693 0.06020806319610725 0.24089870283456208 43.68451445384161 0.030087288687681187 0.019379280185927012 3.195925933508848e-08 7.495403294139377 0.09803792463569905 ADEHVIDQGDDGDNFYVIER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ADEHVIDQGDDGDNFYVIER 20 0 P13861-2;P13861;H7C1L0 P13861-2 PRKAR2A cAMP-dependent protein kinase type II-alpha regulatory subunit 0 ;; 190.8 3.9227e-12 7673800.0 33175.4 36801.4 35620.1 39132.4 47822.0 36225.6 38647.8 38642.0 35270.4 30935.1 False True 38791.33997598236 40454.79978002038 36469.41827398151 36939.93849695254 38451.6223930994 34325.865764475864 34986.800598158654 37627.68844458335 35786.162874958776 36543.38874788316 1.0615145804787853 1.1070347104129417 0.9979758178856377 1.0108514771797772 1.0522183002343148 0.9393180802495842 0.9574043841291354 1.029671569437112 0.979278717741571 1.0 15.157322803965817 -5.271841267580229 23.998983681966333 0.9960578095576419 1.0842746441527003 0.5424818123472805 0.032485415015994744 275.2162804333374 634974.5033927815 0.00882337068565438 0.018699657881777076 5.3475977565559265e-06 5.271841267580229 0.08821683459505836 ADEHVIDQGDDGDNFYVIER ddPTM_PC-9_Lapatinib_30min_R1 2 ADEHVIDQGDDGDNFYVIER 20 0 P13861-2;P13861;H7C1L0 P13861-2 PRKAR2A cAMP-dependent protein kinase type II-alpha regulatory subunit 0 ; 160.47 6.108099999999999e-06 9280300.0 46875.0 37646.0 58043.0 47585.0 46630.0 51877.0 41848.0 41841.0 54384.0 42501.0 False True 46206.55390417779 37558.83299996333 53270.928592459335 51084.559638906605 43887.3150781073 49658.34164119351 44014.68467616339 43785.08560808017 48258.701231091545 49847.24122097727 0.9269631131508365 0.753478669631117 1.0686835878500187 1.0248222045517865 0.8804361887060292 0.9962104306044471 0.8829913872473377 0.8783853335829956 0.9681318373700245 1.0 15.605226040904094 -4.844651616501574 0.00818475244259087 1.834451092175986 3.9229716277151415e-07 0.048803870141117756 0.08548154332661782 40427.49253363928 52.78432697262699 5576.9804886821885 6267.310340193048 1.4300406523209312e-05 4.844651616501574 -1.8344506998788233 ADEWLMK ddPTM_PC-9_Lapatinib_30min_R1 1 ADEWLMK 7 0 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580 P35579 MYH9;MYH10 Myosin-9;Myosin-10 0 102.72 0.012309 0.0 21811.0 23935.0 28800.0 28307.0 29507.0 25490.0 23820.0 22928.0 27119.0 25910.0 False True 21499.971140352474 23879.57997806201 26432.17517121494 30388.791209383835 27771.45627299403 24399.852120092193 25053.283047844885 23993.318582779164 24064.57264426986 30388.50897709516 0.7075033249100088 0.785809530703229 0.8698082288649884 1.0000092874674729 0.9138801872091292 0.8029302174214332 0.824432783679133 0.7895523469369206 0.7918971168479552 1.0 14.89123826980545 -5.004811404548546 2.8224967976206417 0.8677627805590068 0.7084375351732408 0.34071974663137605 0.07432016532704433 0.3806007573230997 5.571650680183051 0.021033513612143128 0.11067963307938332 9.889824740562034e-06 5.004811404548546 -0.15932524538576598 ADFCIIHYAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADFCIIHYAGK 11 0 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580 P35579 MYH9;MYH10 Myosin-9;Myosin-10 0 72.434 0.030018 0.0 49744.0 50122.0 52431.0 64138.0 66919.0 60134.0 61043.0 55562.0 51094.0 44730.0 False True 58164.67671121571 55097.78091524189 53681.153885674794 60544.555798201545 53806.70233206096 56980.46718014311 55260.56512695155 54103.556372805244 51841.1530896487 52839.19491751482 1.1007865809086284 1.0427445195039944 1.0159343640544547 1.1458266139882574 1.0183104117323605 1.0783750068314453 1.045825266891682 1.0239284769055277 0.9811117139573357 1.0 15.689320864730758 -7.866109656086424 1.9014547541237792 0.9906983444850683 1.0649989131867277 0.4022563154974883 0.03667716217705744 0.3613723658202752 2.4717566193283544 0.027862676537959357 0.010317875931788833 1.3611009713294283e-08 7.866109656086424 0.07430056870165935 ADFCIIHYAGK ddPTM_PC-9_Lapatinib_30min_R1 1 ADFCIIHYAGK 11 0 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580 P35579 MYH9;MYH10 Myosin-9;Myosin-10 0 78.342 0.01959 0.0 85772.0 85044.0 94701.0 77323.0 81690.0 89598.0 90719.0 75440.0 88911.0 75891.0 False True 84548.87555134154 84847.08584308793 86915.0493364314 83009.59136196655 76885.15480871935 85766.1024031392 95415.98592852388 78945.21780726002 78896.9069056631 89008.65823159911 0.9498949566383386 0.9532453081397673 0.9764785927935216 0.9326013110542226 0.8637941110028353 0.9635703324498743 1.0719854430369347 0.8869386346870416 0.8863958683701826 1.0 16.441658059226654 ADFDNTVAIHPTSSEELVTLR ddPTM_PC-9_Lapatinib_30min_R1 2 ADFDNTVAIHPTSSEELVTLR 21 0 P00390-5;P00390-4;P00390-2;P00390-3;P00390 P00390-5 GSR Glutathione reductase, mitochondrial 0 ; 151.58 4.2095e-05 8296700.0 19366.5 20313.6 29665.0 24518.3 30614.0 34711.0 24908.9 20808.8 29334.0 18518.8 False True 19090.330158618865 20266.56510726385 27226.05821021149 26321.457572651118 28813.34470943976 33226.49144529306 26198.560961816256 21775.65281425918 26030.096019285807 21719.749905250086 0.8789387650363488 0.9330938521702328 1.2535161928190721 1.2118674334407833 1.3265965232166423 1.5297824141732668 1.2062091449535317 1.0025738283936494 1.1984528428199732 1.0 14.406719870696662 -5.22340806355513 5.091672532560774 1.2312725536664102 0.8969489253878914 0.42344666774794626 0.1440811418600019 0.18917634898627037 12.66554075314071 0.039891020470072994 0.10723826550157647 5.978495909630308e-06 5.22340806355513 -0.3343236282785188 ADFS(ph)PFGNSQGPSR ddPTM_PC-9_AZD4547_30min_R2 1 ADFSPFGNSQGPSR 14 0 Q9H2M9 Q9H2M9 RAB3GAP2 Rab3 GTPase-activating protein non-catalytic subunit 1 ADFS(0.885)PFGNS(0.009)QGPS(0.106)R 67.846 0.033378 5917800.0 18325.0 18906.0 24805.0 34852.0 28409.0 41057.0 24842.0 34986.0 24586.0 33815.0 True False 24151.968816321416 25016.99477301949 24476.069492700914 26817.409858032373 24464.900725035033 38489.6992995872 27052.889874669243 29579.717598300325 25885.565766686203 32631.14714248495 0.7401507740705856 0.7666599848231501 0.7500830230033094 0.8218347256053639 0.7497407497875652 1.1795386515687203 0.8290511441887695 0.9064872120229037 0.793277835242998 1.0 14.993962085572045 ADFTVVAGDEGSS(ph)TTGGSSEENKGPSGSAVSR ddPTM_PC-9_AZD4547_30min_R2 1 ADFTVVAGDEGSSTTGGSSEENKGPSGSAVSR 32 1 P49916-4;P49916-3;P49916-2;P49916 P49916-4 LIG3 DNA ligase 3 1 ADFT(0.002)VVAGDEGS(0.212)S(0.559)T(0.184)T(0.005)GGS(0.005)S(0.033)EENKGPSGSAVSR 57.287 0.00054774 4083800.0 2087.5 6259.0 6897.8 6828.8 8539.0 9138.8 7496.5 8453.5 6080.9 8085.5 True False 2751.2815773026455 8282.099348584 6806.330665057543 5254.5256639082845 7353.5072438689895 8567.34939131128 8163.673977355204 7147.205817104889 6402.323959596604 7802.429106034659 0.3526185935063111 1.0614770395258508 0.8723348296485386 0.6734474088132706 0.942463833241566 1.098036172438274 1.046299026420009 0.9160231666285826 0.8205552235834906 1.0 12.92970762833661 -6.398795213596092 6.154095359139511 0.9798364642193472 0.7733263836510896 0.27393390932634354 0.18117553547743143 0.36842222771729827 16.98855027558484 0.05634954477155184 0.06385122116315449 3.992131021829968e-07 6.398795213596092 -0.2065100805682576 ADFTVVAGDEGSSTT(ph)GGSSEENKGPSGSAVSR ddPTM_PC-9_Lapatinib_30min_R1 1 ADFTVVAGDEGSSTTGGSSEENKGPSGSAVSR 32 1 P49916-4;P49916-3;P49916-2;P49916 P49916-4 LIG3 DNA ligase 3 1 ADFTVVAGDEGS(0.055)S(0.055)T(0.188)T(0.233)GGS(0.233)S(0.233)EENKGPS(0.001)GSAVSR 54.934 0.015057 0.0 7418.9 7585.5 8390.0 9265.0 10598.0 8414.9 10627.0 8237.8 9143.2 9661.1 True False 7313.105125540368 7567.936240801728 7700.206586336573 9946.37900713396 9974.646476469678 8055.014343089988 11177.214061689645 8620.558261567427 8113.39653383562 11331.008262393434 0.6454063889276196 0.6678961011721266 0.6795694088312375 0.8778017610440786 0.8802964613109148 0.7108823995675507 0.9864271389498305 0.7607935729936991 0.716034826376681 1.0 13.4679886211523 -5.717008091428579 7.21420269495142 0.838908427186346 0.6630689776559886 0.4399927179775075 0.09438483206095072 0.20440849347030796 26.279841014411083 0.025083226494566797 0.04319803273192444 1.918632993896827e-06 5.717008091428579 -0.17583944953035735 ADGAPSAAPPDGLLAS(ph)PDLGLLK ddPTM_PC-9_AZD4547_30min_R2 1 ADGAPSAAPPDGLLASPDLGLLK 23 0 P17535 P17535 JUND Transcription factor jun-D 1 ADGAPSAAPPDGLLAS(1)PDLGLLK 139.31 2.5860000000000003e-06 819020.0 7937.5 8456.5 10835.0 12888.0 12034.0 13792.0 8277.6 12706.0 9742.0 10685.0 True False 10461.459889743586 11189.898249129337 10691.320820536763 9916.87071761509 10363.286821960353 12929.584059719582 9014.290364164006 10742.579654833478 10256.942231312823 10310.921402260878 1.0145999064108568 1.0852471677919808 1.0368928637349981 0.9617831744348876 1.0050786362980124 1.2539698010775748 0.8742468313440388 1.0418641783534448 0.9947648547746453 1.0 13.331885639808938 ADGAPSAAPPDGLLAS(ph)PDLGLLK ddPTM_PC-9_Lapatinib_30min_R1 2 ADGAPSAAPPDGLLASPDLGLLK 23 0 P17535 P17535 JUND Transcription factor jun-D 1 ADGAPSAAPPDGLLAS(1)PDLGLLK;ADGAPSAAPPDGLLAS(1)PDLGLLK 144.44 1.5045999999999999e-07 4317100.0 27705.0 41832.0 46127.0 38729.0 85454.0 97013.0 106077.0 94766.0 92130.0 85952.0 True False 27309.921619525245 41735.14057415042 42334.61611536915 41577.25985615665 80427.76372902798 92863.98013834846 111569.14802125283 99169.17432029158 81753.34922809033 100808.68867615928 0.2709084105563204 0.41400340706961863 0.41995007247208704 0.4124372651024222 0.7978257111090536 0.9211902402249014 1.1067413879339385 0.9837363785066731 0.8109752274500578 1.0 16.621260464165438 -6.37180255489733 2.074613835661687 0.9755818976846672 0.3676075809998664 0.9257329023547324 0.07860162402487263 0.08315883909597915 0.704459849119197 0.02864554383400096 0.034306541369522596 4.248126543903098e-07 6.37180255489733 -0.6079743166848008 down ADGAT(ph)SDDLDLHDDR ddPTM_PC-9_Lapatinib_30min_R1 1 ADGATSDDLDLHDDR 15 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 ADGAT(0.643)S(0.357)DDLDLHDDR 149.73 0.00028386 7492800.0 21201.0 22693.0 31768.0 22233.0 29687.0 32101.0 26973.0 23280.0 26417.0 23442.0 True False 20898.66985221277 22640.455752753773 29156.15766802626 23868.088987113817 27940.869026887638 30728.11506108588 28369.5299600974 24361.673787818334 23441.63927665758 27493.91846549843 0.7601197289661746 0.8234714080921142 1.0604584320934005 0.8681224910543546 1.0162563427235765 1.1176331631173626 1.0318474609466002 0.8860749993999332 0.8526117987173791 1.0 14.746824915642822 -5.1010180912882745 4.98573367263785 0.9788163853035566 0.7736851418767644 0.45962756657874326 0.08236208182149742 0.19292433844778697 7.303851769155501 0.022675519417811627 0.06584290185778803 7.924683181535709e-06 5.1010180912882745 -0.20513124342679223 ADGATS(ph)DDLDLHDDR ddPTM_PC-9_AZD4547_30min_R2 1 ADGATSDDLDLHDDR 15 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 ADGAT(0.202)S(0.798)DDLDLHDDR 148.36 7.2394e-05 4094300.0 24463.0 36315.0 37635.0 34183.0 34165.0 38618.0 36363.0 47101.0 42095.0 37497.0 True False 32241.725137990226 48053.113571469534 37135.935309727865 26302.63747208541 29421.779480827292 36203.21035515158 39599.2365555349 39822.62272330486 44320.05576135428 36184.241443198516 0.8910432788428855 1.328012185826877 1.0263013352932464 0.7269086326812986 0.8131103018150363 1.000524231300602 1.0943779661015471 1.1005515421904815 1.2248441308608677 1.0 15.143073907199591 -7.243291157486797 3.6748825387175423 1.1162833361117868 0.964069576704144 0.16342166728488394 0.1570969795758464 0.48938497842398454 14.536242363195393 0.073370012064356 0.05208749582111114 5.710956372837951e-08 7.243291157486797 -0.1522137594076428 ADGATS(ph)DDLDLHDDR ddPTM_PC-9_Lapatinib_30min_R1 1 ADGATSDDLDLHDDR 15 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 ADGAT(0.199)S(0.801)DDLDLHDDR 149.86 7.7123e-05 6641200.0 22163.0 29672.0 25970.0 27258.0 29432.0 31968.0 25438.0 32830.0 29026.0 23554.0 True False 21846.951555803564 29603.29630704226 23834.846847099023 29262.644250022404 27700.867625538365 30600.803161047723 26755.055170910073 34355.40165180738 25756.7862226696 27625.277516267823 0.7908319307539426 1.0716017708640078 0.8627912184072464 1.0592705985592499 1.00273626606017 1.1077102535179126 0.9684990550829653 1.2436219557098152 0.9323629855845642 1.0 14.753701337061024 -3.456489494567364 0.5790869049745986 1.0564397913363095 5.230329994756206e-15 0.2792379410999325 0.10313922744439463 19.790335326688997 1.5303505472627603 0.04639167854027938 19.72376829178035 0.0003495509650127364 3.456489494567364 -1.0564397913363042 ADGATSDDLDLHDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ADGATSDDLDLHDDR 15 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 0 ; 147.51 0.00010322 18617000.0 94295.0 126362.0 105488.0 111183.0 143158.0 112461.0 124191.0 108635.0 106502.0 103454.0 False True 110257.28108885688 138906.38426263476 108003.23398546774 104953.77697014956 115107.21756830145 106563.34718372436 112426.7294150226 105783.4463582971 108059.39026801128 122209.39125858636 0.9021997405711671 1.1366261040341716 0.8837556007209021 0.8588028783162405 0.9418852052437017 0.8719734718115395 0.9199516359355366 0.8655917951057204 0.8842151094539479 1.0 16.898995628673624 -5.3048934991895464 24.993789836734784 0.8977404080257507 1.0194131183535515 0.3267245267294435 0.06630920504607539 393.2886566655117 226209.71804833494 0.015778295965898644 0.03284558249014321 4.95571703555695e-06 5.3048934991895464 0.1216727103278008 ADGGTGDS(ph)SPSPGSSLPSPLSDPR ddPTM_PC-9_AZD4547_30min_R2 1 ADGGTGDSSPSPGSSLPSPLSDPR 24 0 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 ADGGT(0.003)GDS(0.421)S(0.421)PS(0.146)PGS(0.004)S(0.004)LPS(0.001)PLS(0.002)DPR 72.801 0.00045670000000000004 8735300.0 3833.4 6290.0 7911.0 10925.0 7486.7 7846.6 6829.4 10217.0 9034.9 7940.2 True False 5052.341460326685 8323.119492345957 7806.0949710444265 8406.410039567414 6447.300934848807 7355.950861586105 7437.203369699142 8638.19741330345 9512.466368886084 7662.216014808785 0.659383845425659 1.0862548740807936 1.0187777212176694 1.097125168922453 0.8414407688830609 0.9600291674587664 0.970633476702463 1.1273758657558572 1.2414771849946953 1.0 12.903545983759875 -7.760322374523258 4.97613499316134 1.1412165967953125 0.9569046483234586 0.2688682735207645 0.1311849327515488 0.23707687588634047 16.0516002119768 0.06819865842313166 0.034716562680301634 1.7365113469271026e-08 7.760322374523258 -0.18431194847185395 ADGGTGDSS(ph)PSPGSSLPSPLSDPR ddPTM_PC-9_AZD4547_30min_R2 2 ADGGTGDSSPSPGSSLPSPLSDPR 24 0 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 ADGGTGDS(0.133)S(0.861)PS(0.006)PGSSLPSPLSDPR;ADGGT(0.001)GDS(0.198)S(0.785)PS(0.015)PGSS(0.001)LPSPLSDPR 152.86 6.3825e-07 15086500.0 27258.0 27676.0 39604.0 53355.0 44237.0 40155.0 37455.0 46139.0 39939.0 37773.0 True False 35925.476998378675 36621.725766322204 39078.82508320607 41054.82907653269 38095.45613620242 37644.10150217805 40788.42244005056 39009.27771874403 42050.09400291551 36450.5787672064 0.9855941445489435 1.0046953163681938 1.0721043781714719 1.1263148752378276 1.0451262346066195 1.0327435880399634 1.1190061672421727 1.0701963874943905 1.153619377938296 1.0 15.153654101589987 -5.236885328139354 3.7574222029816626 1.0808981446387174 0.9907339359044118 0.3637161963359038 0.04372287146866406 0.22429676721358413 6.99277897703223 0.011175960715213658 0.03133067094559069 5.7958170997480325e-06 5.236885328139354 -0.09016420873430553 ADGGTGDSS(ph)PSPGSSLPSPLSDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ADGGTGDSSPSPGSSLPSPLSDPR 24 0 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 ADGGTGDS(0.128)S(0.871)PS(0.001)PGSSLPSPLSDPR;ADGGT(0.001)GDS(0.114)S(0.609)PS(0.264)PGS(0.01)S(0.002)LPSPLSDPR 169.62 3.1838e-10 12141500.0 31189.1 29010.9 41265.0 42707.0 49441.0 53268.0 49248.0 58873.0 51384.0 37894.0 True False 36468.79861719561 31890.910425641225 42248.91409838398 40314.26524796211 39753.39096518815 50474.53230704533 44582.872915356515 57327.64613109969 52135.39379102258 44763.88223126103 0.8146924886628238 0.7124250363470505 0.9438170237361426 0.9005980544692008 0.8880684378493475 1.1275727169123022 0.9959563534956737 1.2806674326174665 1.1646754301085536 1.0 15.450047541710665 -6.502658368677844 0.8174561609529692 1.1540388227947875 0.7872220226733118 0.6473886998719498 0.09608831414604391 0.3719616506017774 0.5500114963483971 0.05626172268362752 0.07137676846651064 3.1429801004486144e-07 6.502658368677844 -0.3668168001214758 ADGGTGDSS(ph)PSPGSSLPSPLSDPR ddPTM_PC-9_Lapatinib_30min_R1 3 ADGGTGDSSPSPGSSLPSPLSDPR 24 0 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 ADGGTGDS(0.141)S(0.857)PS(0.002)PGSSLPSPLSDPR;ADGGTGDS(0.068)S(0.926)PS(0.004)PGS(0.001)SLPSPLSDPR;ADGGTGDS(0.106)S(0.874)PS(0.002)PGS(0.014)S(0.003)LPSPLSDPR 181.64 1.5500999999999998e-45 5019200.0 52090.8 51186.3 52853.2 47359.600000000006 66212.0 68303.0 62917.0 60997.0 74354.0 63563.0 True False 51347.97563971722 51067.78126722687 48507.81391525198 50842.58297099425 62317.54033780054 65381.83991206962 66174.53440475464 63831.143300496355 65979.46953766885 74549.77985762648 0.6887743429662764 0.6850158560461881 0.6506768230287351 0.6819950785648501 0.8359185024665828 0.8770225752099391 0.887655664860893 0.8562217544089287 0.8850390928541303 1.0 16.185916471846504 -6.360531287102252 2.618334613753687 0.8908419648941599 0.6721535574360703 0.8866300122307489 0.03792678896625705 0.08895490848373852 1.1899609302571357 0.01222975321902961 0.014445278544897876 4.3598215418479765e-07 6.360531287102252 -0.2186884074580896 ADGGTGDSSPS(ph)PGSSLPSPLSDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADGGTGDSSPSPGSSLPSPLSDPR 24 0 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 ADGGT(0.005)GDS(0.002)S(0.052)PS(0.928)PGS(0.013)SLPSPLSDPR 168.62 2.4853999999999997e-34 0.0 4479.0 3737.1 3835.4 6066.0 7001.1 5111.6 6960.6 4729.3 4799.6 5547.1 True False 5237.20623571758 4108.094590366514 3926.850481835499 5726.141686237344 5629.284712816866 4843.538697542478 6301.241577620016 4605.160886107551 4869.785070048889 6552.745319180564 0.7992384841186693 0.6269272480866448 0.5992679847240822 0.8738538440485906 0.8590727151167262 0.7391617500171933 0.9616185691172262 0.7027834383594564 0.7431671509946409 1.0 12.67788374529364 -5.767273588219773 24.998034877319267 0.8292337111393842 0.670322833821367 0.349295327500439 0.10228857871700034 155.69212086210223 667102.80312447 0.028130547149034756 0.04301141190456206 1.7089384128132089e-06 5.767273588219773 -0.15891087731801712 ADGGTGDSSPSPGS(ph)SLPSPLSDPR ddPTM_PC-9_Lapatinib_30min_R1 1 ADGGTGDSSPSPGSSLPSPLSDPR 24 0 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 ADGGTGDS(0.05)S(0.368)PS(0.016)PGS(0.532)S(0.034)LPSPLSDPR 188.34 1.3341000000000001e-20 7049100.0 24528.0 22927.0 24942.0 18573.0 25503.0 26100.0 28285.0 29013.0 35436.0 28373.0 True False 24178.22622211569 22873.913940130682 22891.36503890426 19938.920377711718 24002.963680827135 24983.76384207162 29749.458900432084 30361.04989716379 31444.824522377196 33277.235245353935 0.7265695615590955 0.6873742296041335 0.6878986451285878 0.5991759901536751 0.7213028216993584 0.7507764289270329 0.8939882980388406 0.9123669581715839 0.9449350070861859 1.0 15.022247955350931 -7.261922426858759 1.3739910845684755 0.9596227376635923 0.6757857069434835 0.9213341541304679 0.035641695048950935 0.11551451822703597 0.4253610937579442 0.0226421543457193 0.013218342593738457 5.471136789329177e-08 7.261922426858759 -0.2838370307201088 ADGGTGDSSPSPGSSLPS(ph)PLSDPR ddPTM_PC-9_AZD4547_30min_R2 1 ADGGTGDSSPSPGSSLPSPLSDPR 24 0 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 ADGGTGDSSPSPGS(0.011)S(0.282)LPS(0.698)PLS(0.008)DPR 186.7 1.7952e-20 5196200.0 6426.9 6054.9 8588.4 9978.5 10014.0 7756.3 6126.2 8508.0 5467.5 7144.1 True False 8470.5205121755 8012.028014977027 8474.512204439125 7678.110991288193 8623.728954222284 7271.297334860998 6671.419931978051 7193.284094390303 5756.500887877526 6893.987233494801 1.228682361206158 1.162176218727265 1.2292613718901682 1.1137402393180662 1.250905849132334 1.0547303162287587 0.96771573633972 1.0434141884454546 0.8350031256091195 1.0 12.751122911741103 -6.970571466116876 3.5610960964736504 0.9675173823112806 1.1919385013159296 0.7625950838878888 0.0619699634643554 0.11201121821060955 3.015316985889594 0.02248759733083141 0.018790535306339923 1.0701102744829938e-07 6.970571466116876 0.224421119004649 ADGGTGDSSPSPGSSLPS(ph)PLSDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ADGGTGDSSPSPGSSLPSPLSDPR 24 0 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 ADGGTGDSSPSPGS(0.002)S(0.007)LPS(0.927)PLS(0.064)DPR;ADGGTGDSSPSPGS(0.001)S(0.016)LPS(0.981)PLS(0.002)DPR 186.13 1.9569999999999997e-20 11120500.0 33566.0 38945.0 40932.0 46483.0 60121.0 51603.0 51076.0 51197.0 48883.0 42395.0 True False 39248.06084128073 42811.2022214615 41907.97411547445 43878.708209919285 48340.72163220963 48896.84783811029 46237.71152178263 49853.13299770545 49597.821397449705 50080.87790136462 0.7836935470376665 0.8548412890400822 0.8368059002083214 0.8761569295238665 0.9652530797766312 0.9763576416214927 0.9232608025132628 0.9954524578401417 0.9903544721227471 1.0 15.611972232012553 -6.0746122172609205 1.4401671696730654 0.9770849911855178 0.818725627569419 0.8774605399781147 0.025710821236437434 0.13919352719838934 0.5821715497803294 0.0093726272670951 0.015443028225910265 8.42146761196292e-07 6.0746122172609205 -0.1583593636160988 ADGGTGDSSPSPGSSLPS(ph)PLSDPR ddPTM_PC-9_Lapatinib_30min_R1 3 ADGGTGDSSPSPGSSLPSPLSDPR 24 0 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 ADGGTGDSSPSPGSSLPS(0.999)PLS(0.001)DPR;ADGGTGDSSPSPGSSLPS(0.992)PLS(0.008)DPR;ADGGTGDSSPSPGS(0.06)S(0.263)LPS(0.65)PLS(0.026)DPR 143.64 7.1196e-09 9799700.0 35981.5 38514.8 43946.2 34229.0 50804.0 45374.2 40991.6 44387.5 50690.2 43874.6 True False 35468.39721180104 38425.621346942266 40333.11307323772 36746.3148445967 47815.80860450701 43433.65123842629 43113.94447456078 46449.90529453548 44980.935884529994 51458.266150770294 0.6892652991431991 0.7467336974463346 0.7838024109686013 0.7140993584379958 0.9292153074961551 0.8440558628844536 0.8378429298072142 0.9026714028498248 0.8741245916202846 1.0 15.651115226869383 -2.0338908976867978 0.12498424379153676 1.0491311269961208 4.282291315841257e-12 0.7615223834909426 0.04593787727649737 38.02799705173955 0.36770947729282405 0.2922988126663402 6.857697687749565 0.009249305033536367 2.0338908976867978 -1.0491311269918384 ADGYEPPVQES(ph)V ddPTM_PC-9_AZD4547_30min_R2 2 ADGYEPPVQESV 12 0 D6RAT0;P61247;D6R9B6;H0Y9Y4 D6RAT0 RPS3A 40S ribosomal protein S3a 1 ADGYEPPVQES(1)V;ADGYEPPVQES(1)V 104.59 0.0018920000000000002 11202700.0 54553.0 56934.0 71313.0 99411.0 85328.0 75550.0 50511.0 79402.0 70412.0 71474.0 True False 71899.71922710967 75336.80209494829 70367.34302491354 76493.32983463957 73481.68006849206 70825.84655683103 55006.38114722722 67132.24537644311 74133.83457105291 68971.71701499242 1.0424522157608573 1.092285437501466 1.0202347581055253 1.109053582325813 1.0653885860565036 1.0268824617115966 0.797520832129936 0.9733300587812036 1.074843976335088 1.0 16.07371726191581 -7.011703555351917 24.712266436620354 0.9524869975036109 1.0651044465748394 0.3383972932555571 0.068464945285856 539.4404351757823 1139037.5582393783 0.02565221020337878 0.02104294715747606 9.734114370250657e-08 7.011703555351917 0.1126174490712285 ADGYEPPVQES(ph)V ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ADGYEPPVQESV 12 0 D6RAT0;P61247;D6R9B6;H0Y9Y4 D6RAT0 RPS3A 40S ribosomal protein S3a 1 ADGYEPPVQES(1)V;ADGYEPPVQES(1)V;ADGYEPPVQES(1)V 139.48 7.2537e-05 12477800.0 91452.0 81640.0 88425.0 103116.0 119385.0 99549.0 107743.0 107197.0 97060.0 82004.0 True False 106933.01734066628 89744.67966003648 90533.38735367983 97338.74482658278 95992.36626239326 94328.47519400115 97536.8030482306 104383.19233461015 98479.31888052005 96870.67605669312 1.1038739657198657 0.9264380441353978 0.9345799063144309 1.0048318932926177 0.9909331716257886 0.9737567552310241 1.0068764565155677 1.0775520166032533 1.0166060864784867 1.0 16.5637723897704 -7.528359165175296 24.628576081788342 1.0366902905480788 0.9850273903088758 0.12410967016768826 0.04906681745303466 215.30001734452946 967515.624354686 0.022505458060838607 0.013048515163581754 2.96238046273238e-08 7.528359165175296 -0.05166290023920306 ADGYEPPVQES(ph)V ddPTM_PC-9_Lapatinib_30min_R1 4 ADGYEPPVQESV 12 0 D6RAT0;P61247;D6R9B6;H0Y9Y4 D6RAT0 RPS3A 40S ribosomal protein S3a 1 ADGYEPPVQES(1)V;ADGYEPPVQES(1)V;ADGYEPPVQES(1)V;ADGYEPPVQES(1)V 132.79 7.6777e-05 20442200.0 127990.0 122296.0 136149.0 115858.0 128249.0 120653.0 106107.0 100359.0 126911.0 98218.0 True False 126164.83912950891 122012.83112584407 124955.3547703381 124378.58381095814 120705.64596723541 115492.95244588012 111600.70127446177 105022.04551854197 112616.9467479232 115194.85043274127 1.0952298532057445 1.059186505885379 1.0847303876946799 1.0797234715242672 1.0478389052443948 1.0025878067640959 0.9687993938550403 0.9116904542522161 0.9776213634972926 1.0 16.813716699713567 -6.844044580254653 1.7058889874001737 0.956443257022278 1.0787500050727181 0.8391936048066908 0.022862133746540662 0.12737223173664267 0.7643083681726728 0.009808190749681273 0.008390803776141157 1.4320408929746492e-07 6.844044580254653 0.12230674805044017 ADGYVLEGK ddPTM_PC-9_Lapatinib_30min_R1 3 ADGYVLEGK 9 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 0 ;; 113.22 0.0097487 32667200.0 214982.0 210734.0 232582.0 230240.0 234077.0 209504.0 207854.0 190604.0 198212.0 209269.0 False True 211916.31725713 210246.05837045822 213460.00575248254 247172.61765812448 220309.05107308863 200544.00229767733 218615.66308256722 199460.15767411145 175887.27729510728 245440.8678165847 0.8634108864685597 0.856605748833861 0.8697003382175086 1.0070556703003262 0.8976054111645465 0.8170766510145396 0.8907060385963772 0.8126607416624922 0.7166177289861358 1.0 17.90501596340264 -6.744538262909858 21.41220133737353 0.8384094393069906 0.9009165849911717 0.09300034824742087 0.07772953119129117 96.79098214224044 122623.07411764181 0.025666044466293933 0.025555633790093204 1.8007844718473165e-07 6.744538262909858 0.06250714568418103 ADHDFVVQEDFMK ddPTM_PC-9_Lapatinib_30min_R1 1 ADHDFVVQEDFMK 13 0 P62333;A0A087X2I1 P62333 PSMC6 26S protease regulatory subunit 10B 0 77.89399999999999 0.01059 3269400.0 21771.0 16477.0 19841.0 18449.0 21809.0 18089.0 17605.0 17047.0 16287.0 17351.0 False True 21460.541547687557 16438.848518843857 18209.74956847485 19805.80100405986 20526.237498143713 17315.375637518548 18516.50075807343 17839.06585313313 14452.586550286629 20350.097231245774 1.0545670275588066 0.8078019643858733 0.8948237132014971 0.9732533844432844 1.0086555000153754 0.8508743442725335 0.9098974097107989 0.8766083842460871 0.7101974199954171 1.0 14.312748067146671 -6.796407174739539 24.994150469464657 0.8643273585439785 0.9385102965235123 0.1507429596392632 0.0911928398170364 379.57343835514354 271307.4796586875 0.031897400380503246 0.028132028449586212 1.5980590586029443e-07 6.796407174739539 0.07418293797953379 ADHGEPIGR ddPTM_PC-9_AZD4547_30min_R2 1 ADHGEPIGR 9 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 72.243 0.027537 69131000.0 80607.0 80457.0 115990.0 153140.0 116950.0 112870.0 98072.0 124200.0 96681.0 104780.0 False True 106238.34927024422 106463.15182761173 114451.89681348027 117835.9389894145 100713.51120394417 105812.22105717438 106800.2180093615 105007.74383207267 101791.36028182668 101111.6840925496 1.050702994650965 1.052926304047748 1.1319354221092797 1.165403781441884 0.9960620486922067 1.0464885636789738 1.0562599067344687 1.0385322406059116 1.0067220341088865 1.0 16.625590193818184 -6.27951370931444 24.998583694371227 1.0286737550433631 1.0991262382040343 0.5058588528706266 0.03673083588686522 796.9038258148096 1102194.8251750749 0.012332876048099062 0.014005419719158457 5.253954297627215e-07 6.27951370931444 0.07045248316067121 ADHGEPIGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ADHGEPIGR 9 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 ; 92.051 0.0061497 45067900.0 144678.0 155489.0 170881.0 154748.0 174864.0 142059.0 182133.0 154598.0 132271.0 119055.0 False True 169169.12787924678 170924.92032899786 174955.45110980136 146077.9712597848 140600.65447172712 134609.1759594231 164880.04371127015 150539.96631012124 134205.21314285306 140638.7290611388 1.202863030749554 1.2153474471082073 1.244006201405193 1.0386752798105952 0.9997292737948796 0.9571273635508004 1.1723658540713429 1.070401924953959 0.9542550195011437 1.0 17.101634412591366 -5.767090064196569 24.844825473323407 1.032386994181454 1.2201997632053347 0.6857600003646223 0.05987794071007355 74.6736096143547 328325.36287860863 0.017607740706919593 0.02695303553022095 1.7096607280680195e-06 5.767090064196569 0.18781276902388067 ADHGEPIGR ddPTM_PC-9_Lapatinib_30min_R1 3 ADHGEPIGR 9 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 ;; 95.775 0.0044633 142300000.0 508751.0 477313.0 565410.0 557220.0 575304.0 525091.0 443995.0 466051.0 547545.0 448391.0 False True 501496.11744649225 476207.8110745236 518924.17234571744 598199.8176314275 541465.7498111828 502634.0819769063 466982.8886157805 487705.4308628235 485874.7161955357 525894.7869065497 0.953605416772475 0.905519170242592 0.9867452297790681 1.1374895369284699 1.0296085135131794 0.9557692802652239 0.8879777861322712 0.9273821361334157 0.923900993682743 1.0 19.004414670169005 -6.953304076235624 5.832987950724453 0.927741576277857 1.0033347861248203 0.21295972512361672 0.06151370273235388 0.3077080190926282 24.537115534528755 0.024562994844197092 0.021419592678335004 1.1135146206273042e-07 6.953304076235624 0.07559320984696327 ADHGVPLPGS(ph)PPPTVALPLPSR ddPTM_PC-9_AZD4547_30min_R2 1 ADHGVPLPGSPPPTVALPLPSR 22 0 A0A1W2PRX0;V9GYJ6;V9GY36;Q9UK80-2;Q9UK80-3;Q9UK80 A0A1W2PRX0 USP21 Ubiquitin carboxyl-terminal hydrolase 21 1 ADHGVPLPGS(0.999)PPPT(0.001)VALPLPSR 64.002 0.021216 0.0 9463.8 7626.9 14682.0 16718.0 15915.0 18413.0 12441.0 12941.0 10728.0 11973.0 True False 12473.091540731384 10092.146272841546 14487.307086951627 12863.923390525226 13705.476962896711 17261.63219921814 13548.22489858949 10941.265804596256 11295.060178353926 11553.828914297566 1.079563461883727 0.8734893296154641 1.2538966254748638 1.1133905033513567 1.1862281382699493 1.4940183316941205 1.172617752875318 0.9469818088665586 0.9776032051484317 1.0 13.496083416494193 -7.7573951686477205 24.830442759329816 0.9717193524499039 1.1707936914718013 0.26774572803526275 0.14597128163888998 135.36262398962896 831109.905405457 0.07835919158696115 0.043102732482430094 1.7482552107687333e-08 7.7573951686477205 0.19907433902189742 ADHGVPLPGS(ph)PPPTVALPLPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADHGVPLPGSPPPTVALPLPSR 22 0 A0A1W2PRX0;V9GYJ6;V9GY36;Q9UK80-2;Q9UK80-3;Q9UK80 A0A1W2PRX0 USP21 Ubiquitin carboxyl-terminal hydrolase 21 1 ADHGVPLPGS(1)PPPTVALPLPSR 91.617 0.00011192 2072200.0 20966.0 18931.0 25871.0 27919.0 35947.0 27853.0 25373.0 27330.0 26421.0 22027.0 True False 24515.129702624425 20810.34456937959 26487.862756313876 26354.78894461927 28903.443397698655 26392.3396475958 22969.485755387872 26612.61645852861 26807.357141378772 26020.32073436393 0.9421532483359568 0.7997727922660175 1.0179683420017374 1.0128541155841182 1.110802733477728 1.0142972454886214 0.8827518303820541 1.0227628141179081 1.0302469909979026 1.0 14.667351124811324 -5.278945977137279 24.67749566408274 1.0113757571081312 0.8709630233444663 0.45893467902548346 0.06102074964617116 540.4825736412453 761869.8876792631 0.016572193981426613 0.03462762356529308 5.260827029257146e-06 5.278945977137279 -0.14041273376366492 ADIDVSGPKVDIDT(ph)PDIDIHGPEGK ddPTM_PC-9_AZD4547_30min_R2 1 ADIDVSGPKVDIDTPDIDIHGPEGK 25 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ADIDVS(0.178)GPKVDIDT(0.822)PDIDIHGPEGK 71.527 0.00023955 3910900.0 14028.0 10756.0 13309.0 45492.0 24535.0 18454.0 23442.0 37218.0 30691.0 34343.0 True False 18488.612199473762 14232.666654955976 13132.513964053878 35004.522244393665 21128.738754927464 17300.06846273673 25528.29258682861 31466.813284557844 32313.263603081665 33140.662023195655 0.557883007482871 0.42946235186835785 0.39626589097291515 1.0562408867962103 0.6375472747086084 0.5220193987261977 0.7703012259972649 0.9494925980215405 0.9750337389296906 1.0 15.016314801904882 -6.543505694190114 0.28931036030182966 1.061264574940489 0.33196770376628476 0.47707100677583836 0.1729951090219768 2.8275106998394426 0.44708359977492934 0.2665284292941525 0.7105365199245228 2.860844850822363e-07 6.543505694190114 -0.7292968711742043 ADIDVSGPKVDIDT(ph)PDIDIHGPEGK ddPTM_PC-9_Lapatinib_30min_R1 1 ADIDVSGPKVDIDTPDIDIHGPEGK 25 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ADIDVS(0.263)GPKVDIDT(0.737)PDIDIHGPEGK 72.145 0.00020979 7575000.0 125100.0 45616.0 42771.0 40604.0 59866.0 45393.0 43408.0 30268.0 61673.0 47631.0 True False 123316.05105946981 45510.37895463867 39254.53348083452 43590.15361097327 56344.79958108447 43451.64720625124 45655.453843024785 31674.361778766528 54726.73729451879 55863.9548856819 2.2074350323356016 0.8146644656249197 0.7026808889768664 0.780291221775735 1.008607423093953 0.7778118698393126 0.8172613975586325 0.5669910382031467 0.9796430884012728 1.0 15.769630092300657 -4.7614448012931785 11.677476990971908 0.8122788539500663 2.2097193415497607 0.9066586822805238 0.13274365033331284 0.016189651178060382 101.9427141978346 0.031894245044342594 0.17867870673125505 1.732029157180823e-05 4.7614448012931785 1.3974404875996944 ADIEISGPK ddPTM_PC-9_Lapatinib_30min_R1 1 ADIEISGPK 9 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 83.99799999999999 0.043972000000000004 0.0 15481.0 23268.0 20418.0 25878.0 26131.0 17657.0 20365.0 20459.0 24078.0 16643.0 False True 15260.238101132303 23214.12437558166 18739.310855759264 27781.15444647737 24594.025955522662 16901.851270477346 21419.4000532897 21409.599829251507 21366.0820874195 19519.720374596465 0.7817856920221267 1.1892652112882314 0.9600194314334108 1.4232352673777322 1.2599579032663832 0.86588593207892 1.097321049801796 1.0968189819519436 1.0945895575033926 1.0 14.252644765592027 -10.177504434571649 14.977448980877636 1.000002889585562 1.094092378157951 0.018509242467298237 0.17677997377376578 0.0 0.0 0.17093960683100623 0.04145894438622312 6.645008876688124e-11 10.177504434571649 0.09408948857238908 ADIKS(ph)PSLDVTVPEAELNLETPEISVGGK ddPTM_PC-9_AZD4547_30min_R2 2 ADIKSPSLDVTVPEAELNLETPEISVGGK 29 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ADIKS(0.69)PS(0.291)LDVT(0.019)VPEAELNLETPEISVGGK;ADIKS(0.703)PS(0.282)LDVT(0.014)VPEAELNLETPEISVGGK 62.845 0.00026228 104742000.0 146026.0 156345.0 177854.0 258690.0 251300.0 220410.0 190293.0 241850.0 205456.0 227500.0 True False 192459.23047051262 206880.46375688838 175495.53975226096 199053.01722065877 216411.33275375052 206627.72785693093 207228.70835361193 204477.63966011957 216315.98471326273 219535.29424561118 0.8766664655533407 0.9423562824728999 0.7993955612254332 0.906701666830677 0.9857701172715962 0.9412050511830706 0.9439425631569249 0.9314112355499183 0.9853357996789949 1.0 17.744093372009914 -6.008519486473695 24.854143580471064 0.9578193214834054 0.8753090382742986 0.5389074790424648 0.03839743501934024 309.586724657713 903172.2118501058 0.0107872246134144 0.015160493365531916 9.805743156871956e-07 6.008519486473695 -0.0825102832091068 ADIKS(ph)PSLDVTVPEAELNLETPEISVGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ADIKSPSLDVTVPEAELNLETPEISVGGK 29 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ADIKS(0.903)PS(0.091)LDVT(0.006)VPEAELNLETPEISVGGK;ADIKS(0.741)PS(0.257)LDVT(0.003)VPEAELNLETPEISVGGK 112.75 1.7263e-12 47516000.0 114947.0 104298.0 96997.0 131149.0 185116.0 191245.0 198713.0 206675.0 171104.0 157432.0 True False 134405.25679326375 114652.01615853109 99309.77634317112 123801.14672079505 148843.84866632504 181215.7755324188 179889.4660824649 201250.00024026373 173606.0723030347 185973.17536897404 0.7227131360563229 0.6164975993503335 0.5340005414551792 0.6656935683072109 0.800351170920302 0.9744188922562812 0.9672871677625606 1.0821453139194952 0.9335006081312384 1.0 17.504735017528006 -6.535529677080672 1.9159880940890177 1.0022755232043674 0.6209960398505815 0.9009987921482163 0.055886239621932114 0.09603327681636088 0.7122488665097382 0.02136647370654801 0.022980986795957246 2.913871011495368e-07 6.535529677080672 -0.3812794833537859 ADIKS(ph)PSLDVTVPEAELNLETPEISVGGK ddPTM_PC-9_Lapatinib_30min_R1 2 ADIKSPSLDVTVPEAELNLETPEISVGGK 29 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ADIKS(0.689)PS(0.294)LDVT(0.017)VPEAELNLETPEISVGGK;ADIKS(0.696)PS(0.271)LDVT(0.033)VPEAELNLETPEISVGGK 82.581 4.3098999999999997e-07 48651000.0 139809.0 109584.0 105142.0 104610.0 166703.0 170108.0 183554.0 171025.0 187481.0 157251.0 True False 137815.29802216953 109330.26498082088 96497.63061985686 112303.36836872996 156897.85729070823 162832.8773811157 193057.52798338007 178971.44585745863 166364.915517547 184431.62582621368 0.7472433071323147 0.59279564711879 0.5232162878116398 0.6089160026954988 0.8507101566113722 0.882890212845328 1.0467701898658879 0.9703945570923933 0.9020411481613756 1.0 17.49272654078146 -6.460751173659302 2.114883955679223 0.968067278936666 0.6062480356709 0.8517195491685958 0.06747685978389888 0.1179090852349114 1.0484898071348485 0.02522327113921071 0.028386233854537472 3.461376384463982e-07 6.460751173659302 -0.361819243265766 ADIKSPS(ph)LDVTVPEAELNLETPEISVGGK ddPTM_PC-9_AZD4547_30min_R2 1 ADIKSPSLDVTVPEAELNLETPEISVGGK 29 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ADIKS(0.206)PS(0.791)LDVT(0.004)VPEAELNLETPEISVGGK 89.87899999999999 1.2251e-08 1500700.0 8853.9 9187.8 11409.0 12373.0 16709.0 12366.0 9857.0 12218.0 12281.0 13189.0 True False 11669.256027439467 12157.576672778398 11257.709205491832 9520.596010944411 14389.243768334347 11592.752065145894 10734.253904460778 10329.988841709068 12930.148587841593 12727.257124419171 0.9168712404694199 0.9552393382115495 0.8845353791031857 0.7480477464918741 1.130584824968013 0.9108602074914824 0.8434066978866551 0.8116429754443649 1.0159414916693357 1.0 13.635633914313287 -8.29897000855187 24.58620234467369 1.0079708824212283 0.9025413020140043 0.16916087203176822 0.09546435645187454 1014.9653208274999 664890.9625640857 0.09318377279658753 0.024062745268174673 5.0237728142516176e-09 8.29897000855187 -0.10542958040722405 ADILEDKDGK ddPTM_PC-9_Lapatinib_30min_R1 1 ADILEDKDGK 10 1 A0A087X0X3;P52272-2;P52272;M0R2T0;M0R019;M0QYQ7;M0R0N3;M0QZM1 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 79.97399999999999 0.02371 3705700.0 51929.0 34532.0 42706.0 36357.0 46372.0 38036.0 39453.0 31397.0 35164.0 37587.0 False True 51188.48293738772 34452.04327563976 39194.877529927246 39030.815063396614 43644.490130859755 36409.28894624663 41495.6832949884 32855.81924038367 31203.46002666416 44083.862868470685 1.1611614683158438 0.7815114428250406 0.8890980730719925 0.8853764739231127 0.9900332523281399 0.8259096770824725 0.9412896374075833 0.7453026368948842 0.7078204584694245 1.0 15.427963025804559 -7.754553676892626 24.99322195630814 0.7949211559964974 0.9151949689352933 0.13028442359973136 0.12095471815918986 267.3757490728205 970510.3707257479 0.05518868396362148 0.030963267384326934 1.759731155309698e-08 7.754553676892626 0.12027381293879591 ADLDVSGPK ddPTM_PC-9_Lapatinib_30min_R1 2 ADLDVSGPK 9 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ; 108.98 0.011056 17388700.0 178938.0 194557.0 213567.0 200565.0 188965.0 182809.0 216426.0 159041.0 177488.0 184950.0 False True 176386.31130678992 194106.51522004677 196008.3456524606 215315.21916522688 177850.45021948408 174990.68521859305 227631.479299449 166430.62546771523 157497.432408502 216918.361069616 0.8131460630489549 0.894836722271527 0.9036042162864917 0.9926094688504741 0.8198957863341325 0.8067121858920601 1.0493877889220953 0.7672500596401904 0.7260677779044996 1.0 17.726792649636714 ADLGEIS(ph)AS(ph)KNT(ph)IMS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 ADLGEISASKNTIMSR 16 1 D6RIA3 D6RIA3 LOC285556 4 ADLGEIS(1)AS(1)KNT(1)IMS(1)R 70.45100000000001 0.005107100000000001 2721700.0 0.0 0.0 0.0 441.06 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 339.38043130907135 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADLGPGS(ph)PPWAVK ddPTM_PC-9_AZD4547_30min_R2 1 ADLGPGSPPWAVK 13 0 A0A087WVC5;A0A0C4DH65;A5PL33-3;A5PL33-2;A5PL33 A0A087WVC5 KRBA1 Protein KRBA1 1 ADLGPGS(1)PPWAVK 94.728 0.014721000000000001 0.0 16759.0 11446.0 16907.0 21663.0 18685.0 14678.0 14558.0 19328.0 12774.0 16981.0 True False 22088.013391144923 15145.695661270562 16682.802133162437 16668.930040013624 16090.910276577126 13760.182339658057 15853.633797417076 16341.30171325526 13449.207561362145 16386.500358614132 1.3479396398104977 0.924278847210271 1.0180820656066776 1.0172355094265764 0.9819613660288593 0.8397267286193015 0.9674813688380426 0.9972417145595636 0.8207492305879762 1.0 14.000220152572624 -4.758829901641954 24.99005332237948 0.9538124588289294 1.3479401642253426 0.7593056472892443 0.0668919185249607 34.28942713445283 328311.66518143914 0.016677676220583755 0.11098880554433099 1.7424892134401694e-05 4.758829901641954 0.3941277053964132 ADLINNLGT(ph)IAK ddPTM_PC-9_AZD4547_30min_R2 2 ADLINNLGTIAK 12 0 P07900;P07900-2;Q14568;P08238;Q58FF8 P07900;P08238 HSP90AA1;HSP90AA2P;HSP90AB1;HSP90AB2P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 ADLINNLGT(1)IAK;ADLINNLGT(1)IAK 128.9 0.00046773 24682000.0 86900.0 109685.0 120027.0 166160.0 129308.0 132104.0 97238.0 122194.0 103645.0 113607.0 True False 114532.39236771228 145138.53124292 118435.36355575139 127854.3791464092 111355.81621855128 123843.5159966066 105891.9936250337 103311.72503877866 109123.4631045387 109629.65350927965 1.0447209190350824 1.3238984763427595 1.080322337657725 1.1662390152093924 1.0157453996616481 1.1296534471498973 0.9659064882118817 0.9423702596125946 0.995382723665198 1.0 16.742278557264363 -6.66420853561933 0.8436738267934638 0.9686510213850071 1.1746376302395802 0.4516871856483554 0.08058627113231001 0.505889026731035 0.7923535761655958 0.0476721917154352 0.049899533016458116 2.166663486011198e-07 6.66420853561933 0.2059866088545731 ADLINNLGT(ph)IAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ADLINNLGTIAK 12 0 P07900;P07900-2;Q14568;P08238;Q58FF8 P07900;P08238 HSP90AA1;HSP90AA2P;HSP90AB1;HSP90AB2P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 ADLINNLGT(1)IAK;ADLINNLGT(1)IAK 142.97 0.00020307 18071200.0 113442.0 114717.0 104569.0 124475.0 118342.0 103740.0 115356.0 118829.0 114558.0 84102.0 True False 132645.4900183687 126105.3456217587 107062.32154014085 117501.06930339483 95153.73462515495 98299.6917761674 104428.64457488354 115709.8646597326 116233.19402755667 99349.02684893427 1.3351463444132528 1.269316364955531 1.0776383517368024 1.18270981639369 0.9577721860309865 0.9894378927902088 1.0511290134091913 1.1646804033186544 1.1699479875559902 1.0 16.60021821549855 -5.109882271948467 1.5176902634642477 1.068485898503156 1.373943720465493 0.599181622651259 0.07525892701679358 0.46939677235154575 1.547286801106425 0.023762191039632667 0.17892563376296677 7.76457569332769e-06 5.109882271948467 0.30545782196233695 ADLINNLGT(ph)IAK ddPTM_PC-9_Lapatinib_30min_R1 1 ADLINNLGTIAK 12 0 P07900;P07900-2;Q14568;P08238;Q58FF8 P07900;P08238 HSP90AA1;HSP90AA2P;HSP90AB1;HSP90AB2P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 ADLINNLGT(1)IAK 101.39 0.0066918 8705200.0 53485.0 48828.0 53021.0 42415.0 52206.0 50077.0 54055.0 54552.0 45058.0 48976.0 True False 52722.29409205222 48714.941765983385 48661.818046978726 45534.3405922922 49135.34572094509 47935.32344518858 56853.70340685371 57086.6850718671 39983.093558225264 57441.43634358211 0.9178442853813291 0.8480801467880821 0.8471553140821778 0.7927089482918148 0.8553989741315887 0.8345077438256706 0.9897681364857781 0.993824122544689 0.6960670920390825 1.0 15.809804204264985 -7.223177545761603 24.927975451079252 0.9194002316158556 0.8468376990402715 0.13720103674119566 0.08663913749173692 1071.3701208235752 698009.1609884594 0.03244080341498255 0.025128152028006383 5.98167005887631e-08 7.223177545761603 -0.0725625325755841 ADLINNLGTIAK ddPTM_PC-9_AZD4547_30min_R2 2 ADLINNLGTIAK 12 0 P07900;P07900-2;Q14568;P08238;Q58FF8 P07900;P08238 HSP90AA1;HSP90AA2P;HSP90AB1;HSP90AB2P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 0 ; 173.72 0.0021783 20018700.0 68427.0 75192.0 103765.0 119828.0 105483.0 91602.0 78774.0 105236.0 83201.0 76153.0 False True 90185.3626299823 99496.34354029853 102389.00830115342 92203.50592414496 90838.5062191161 85874.11245928294 85784.73339454128 88974.19428270526 87598.83500179213 73486.90664916919 1.227230356293707 1.3539329395820119 1.393295934879455 1.2546929804016642 1.2361182469250538 1.1685634404132834 1.1673471820508468 1.210748939365121 1.1920332341650208 1.0 16.165199603715777 -9.026990212093057 0.1353474683244441 0.8007511634880304 1.455535935797833 0.7119936993671644 0.054773568815632494 7.428121696493764 0.46982936054795743 1.3498345329409347 0.7241146429451928 9.397444898067159e-10 9.026990212093057 0.6547847723098026 ADLINNLGTIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ADLINNLGTIAK 12 0 P07900;P07900-2;Q14568;P08238;Q58FF8 P07900;P08238 HSP90AA1;HSP90AA2P;HSP90AB1;HSP90AB2P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 0 ; 202.05 8.6156e-06 36587000.0 137188.0 161238.0 158149.0 147176.0 189179.0 158333.0 175401.0 154762.0 141685.0 140544.0 False True 160411.21881349027 177244.64305518087 161919.8719434222 138930.20587103008 152110.7329828143 150029.73875068364 158785.74748672973 150699.66148389314 143756.87508331443 166023.51465430777 0.9661957774324718 1.0675875849528762 0.9752827620868637 0.83681041303281 0.9161999328802158 0.9036655985935114 0.9564051683723933 0.9077007061179148 0.8658826153791728 1.0 17.341028065843993 -5.530380040328539 24.651603733234 0.9098483650532602 1.0180275629518318 0.446191715645868 0.047737086236422 112.04177154236751 368202.883179859 0.01227997710119196 0.021326700480923232 2.9486278263006374e-06 5.530380040328539 0.10817919789857167 ADLINNLGTIAK ddPTM_PC-9_Lapatinib_30min_R1 2 ADLINNLGTIAK 12 0 P07900;P07900-2;Q14568;P08238;Q58FF8 P07900;P08238 HSP90AA1;HSP90AA2P;HSP90AB1;HSP90AB2P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 0 ; 208.33 2.3119e-07 109150000.0 172160.0 160124.0 161542.0 174148.0 168377.0 156869.0 161512.0 133444.0 162608.0 143484.0 False True 169704.96682972225 159753.24271598915 148260.6403301527 186955.42486069803 158473.39590191876 150160.07854949927 169874.30107571447 139644.29540127248 144293.37470184866 168285.01821958742 1.00843776008796 0.949301633657813 0.881009146855213 1.110945150308915 0.9416964004195196 0.8922961778663046 1.0094439949137555 0.8298082436492179 0.857434465815411 1.0 17.360547219123752 -7.120903991461628 1.29151160812134 0.8988788581011199 0.976502894806651 0.11298799016965377 0.07679487050941497 0.9139600242037885 3.0438959684939424 0.04540796770131459 0.029630020962209146 7.570002249211338e-08 7.120903991461628 0.07762403670553109 ADLLLSTQPGREEGSPLELER ddPTM_PC-9_AZD4547_30min_R2 2 ADLLLSTQPGREEGSPLELER 21 1 F5GZS6;J3KPF3;P08195-2;P08195-3;P08195;P08195-4;F5GZI0 F5GZS6 SLC3A2 4F2 cell-surface antigen heavy chain 0 ; 88.781 0.00090576 2972500.0 10825.6 8921.900000000001 15919.599999999999 18645.3 17599.2 11382.400000000001 10690.9 12095.5 13937.3 13237.8 False True 14267.915613531737 11805.72969773631 15708.495702318147 14346.914152013393 15155.854864304862 10670.656728636317 11642.369388982423 10226.418401939103 14673.997224438119 12774.348651272736 1.1169192264147412 0.9241746894515893 1.2296905408756849 1.1231033803499624 1.1864287783310854 0.835319045998731 0.9113865377255433 0.8005432355973957 1.1487080574535686 1.0 13.640962111296664 -6.758583532114018 24.99994774506433 0.9249875225800617 1.112106585140742 0.36494728656541187 0.11584553619787674 80.01997437823971 700492.236955755 0.03865965331182374 0.03704046645334054 1.7434779850062803e-07 6.758583532114018 0.18711906256068023 ADLLLSTQPGREEGSPLELER ddPTM_PC-9_Lapatinib_30min_R1 2 ADLLLSTQPGREEGSPLELER 21 1 F5GZS6;J3KPF3;P08195-2;P08195-3;P08195;P08195-4;F5GZI0 F5GZS6 SLC3A2 4F2 cell-surface antigen heavy chain 0 ; 168.16 2.1564e-08 12076900.0 29610.0 27656.0 17807.4 16125.7 19530.300000000003 23674.0 19822.2 15944.400000000001 22691.2 18071.6 False True 29187.755970191047 27591.96423117959 16343.344310551825 17311.637771758244 18381.566152047155 22661.518206789424 20848.496525230497 16685.23503189393 20135.478107070914 21195.251981106634 1.3770893592682407 1.3017993018330218 0.7710851621448153 0.8167696136469512 0.8672492390480855 1.069178994757402 0.9836399465226819 0.787215695608011 0.9499994680421635 1.0 14.371453497616532 -5.19312294790574 6.240480183333932 0.9024604391974699 1.349628480011037 0.7750380711259754 0.09356260157990935 0.1073735014590888 7.743982725085364 0.025341782325331186 0.06871056227200045 6.410280771191304e-06 5.19312294790574 0.4471680408135671 ADLNQGIGEPQS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 4 ADLNQGIGEPQSPSR 15 0 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 ADLNQGIGEPQS(0.993)PS(0.007)R;ADLNQGIGEPQS(0.907)PS(0.093)R;ADLNQGIGEPQS(0.993)PS(0.007)R;ADLNQGIGEPQS(0.979)PS(0.021)R 185.71 4.127399999999999e-07 444477000.0 87905.0 105197.0 131078.0 132862.0 129613.0 125464.0 120601.0 146828.0 122094.0 118999.0 True False 115856.96146241373 139199.87301054338 129339.82007515624 102232.71859743752 111618.47223323482 117618.71624627721 131334.25536490532 124139.10637178402 128547.63958015872 114832.88123047643 1.0089180051999385 1.2121952485992313 1.1263308791805329 0.8902739137255501 0.972007939165176 1.024259906970456 1.143699034262753 1.0810414668828996 1.1194323281165084 1.0 16.809176276693115 -10.603186104483239 14.939336930473202 1.0000172299425092 1.0642436633851686 0.0450016126072893 0.08877957927225893 0.0 0.0 0.09304743302843983 0.022567317327578995 2.4935259687053144e-11 10.603186104483239 0.06422643344265944 ADLNQGIGEPQS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ADLNQGIGEPQSPSR 15 0 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 ADLNQGIGEPQS(0.94)PS(0.06)R;ADLNQGIGEPQS(0.984)PS(0.016)R;ADLNQGIGEPQS(1)PSR;ADLNQGIGEPQS(0.996)PS(0.004)R 166.36 0.00025692 390406000.0 79791.0 97986.0 106943.0 84602.0 107688.0 69541.0 86512.0 79374.0 72440.0 61209.0 True False 93298.0403559144 107713.40251308604 109492.92670358595 79862.0242233848 86587.30944477613 65894.14754006611 78316.95706735966 77290.5166037048 73499.29795698434 72305.7071698227 1.2903274721701776 1.4896943371302922 1.514305453737179 1.1045051262110577 1.197516943460778 0.9113270600521491 1.0831365895283824 1.0689407465744634 1.016507559830074 1.0 16.141821904743054 -5.830807277609653 5.462019479698736 1.054749403818594 1.4367312647444157 0.7932662776133131 0.08832378005880234 0.08497576255376686 4.637213834062935 0.025352297103247937 0.038636909004061554 1.4763615376904971e-06 5.830807277609653 0.38198186092582165 ADLNQGIGEPQS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 3 ADLNQGIGEPQSPSR 15 0 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 ADLNQGIGEPQS(0.698)PS(0.302)R;ADLNQGIGEPQS(0.987)PS(0.013)R;ADLNQGIGEPQS(0.813)PS(0.187)R 211.06 1.912e-13 278571000.0 89051.0 124427.0 131632.0 107009.0 117474.0 121655.0 131309.0 109796.0 116160.0 101235.0 True False 87781.11641004671 124138.89692627185 120809.72507421428 114878.7988315595 110564.41028277019 116452.09924165618 138107.53752012856 114897.52299000414 103076.83758097223 118733.33486284182 0.7393131550751907 1.0455269117950272 1.017487845462869 0.9675361933046436 0.9311994008295295 0.9807868984407717 1.163174079795429 0.9676938925595856 0.8681373070169752 1.0 16.85736550873981 -6.999031034628195 24.63163348769948 1.0077621789082942 0.9522863758752084 0.0634952240002028 0.10212419996352146 90.74398538754274 2306658.911478038 0.03679948985728407 0.032179921133763834 1.0022336160327143e-07 6.999031034628195 -0.05547580303308586 ADLNQGIGEPQS(ph)PSRR ddPTM_PC-9_AZD4547_30min_R2 4 ADLNQGIGEPQSPSRR 16 1 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 ADLNQGIGEPQS(0.921)PS(0.079)RR;ADLNQGIGEPQS(0.953)PS(0.047)RR;ADLNQGIGEPQS(0.753)PS(0.247)RR;ADLNQGIGEPQS(0.907)PS(0.093)RR 171.78 3.2349e-05 310499000.0 82238.0 129522.0 154592.0 208772.0 154421.0 145243.0 126157.0 175445.0 137622.0 170391.0 True False 108387.9733433363 171387.453559242 152542.00907138156 160642.84089524648 132982.3096504853 136160.93224955414 137384.7286015073 148334.00657502405 144896.41795911867 164425.6629529843 0.6591913415263446 1.0423400488781873 0.9277262826971192 0.9769937247641235 0.808768578226807 0.8281002478821561 0.8355431027867647 0.9021341554051603 0.8812275125237001 1.0 17.327075961568234 -9.270626668682961 1.6094432551953575 1.0000187035704413 0.8789456431189069 0.12732282621485835 0.0984419397158605 23.407482526853705 47.66237826708484 0.0933739397954727 0.02640753814499622 5.362574408763816e-10 9.270626668682961 -0.12107306045153443 ADLNQGIGEPQS(ph)PSRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADLNQGIGEPQSPSRR 16 1 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 ADLNQGIGEPQS(0.533)PS(0.467)RR 86.189 0.0020839 123330000.0 18082.0 12440.0 21750.0 22355.0 22150.0 16390.0 20825.0 23250.0 16666.0 13221.0 True False 21142.925464220873 13674.96098690413 22268.602487334345 21102.52182588788 17809.86650510543 15530.479547054016 18852.30524005644 22639.71213541127 16909.708721025647 15617.862642621589 1.3537656174873272 0.8755974680930267 1.4258418707411793 1.3511786029093702 1.1403523588753945 0.9944049261049906 1.2070989271353922 1.4496037424241943 1.0827159329009959 1.0 13.93090940883739 ADLNQGIGEPQS(ph)PSRR ddPTM_PC-9_Lapatinib_30min_R1 5 ADLNQGIGEPQSPSRR 16 1 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 ADLNQGIGEPQS(0.986)PS(0.014)RR;ADLNQGIGEPQS(0.973)PS(0.027)RR;ADLNQGIGEPQS(0.991)PS(0.009)RR;ADLNQGIGEPQS(0.536)PS(0.464)RR;ADLNQGIGEPQS(0.967)PS(0.033)RR 172.93 2.3755e-05 177402000.0 131897.9 145122.0 153978.0 133865.7 156309.0 144088.3 119754.7 119677.3 132375.3 117921.3 True False 130017.01175888753 144785.97892526884 141318.5232122682 143710.63014088434 147115.21193531778 137925.9792952327 125955.01240175268 125237.94426146352 117465.79974029351 138303.83958474442 0.9400824456447631 1.0468688314076238 1.0217975410991866 1.0390935679904025 1.0637102511183305 0.9972678973291976 0.9107123329325568 0.9055276023969321 0.8493314436749054 1.0 17.077481683513632 -7.192667054798109 3.628902298083519 0.9074869453178765 1.0249436282045132 0.5372731978517633 0.04631888468882713 0.16862657233265974 4.370593085729169 0.018443917644943936 0.013600880674793692 6.417013385468314e-08 7.192667054798109 0.11745668288663669 ADLNQGIGEPQSPS(ph)RR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ADLNQGIGEPQSPSRR 16 1 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 ADLNQGIGEPQS(0.087)PS(0.913)RR;ADLNQGIGEPQS(0.203)PS(0.797)RR 110.33 0.00026751 43111000.0 65017.0 74328.0 76408.0 67058.0 90323.0 65956.0 67957.0 69358.0 66563.0 54509.0 True False 76023.09395571552 81706.792623361 78229.85649895378 63300.95766496936 72624.8565390806 62497.1512510979 61519.62099392638 67537.42599087553 67536.35795017601 64391.05020699342 1.1806469021910557 1.2689153595212979 1.2149181640534472 0.9830707444820388 1.127871906198432 0.9705875436134783 0.9554063925990264 1.0488635574939014 1.0488469707058914 1.0 15.97457255982628 -5.752638024745521 24.221566558231267 1.021111280708494 1.2262357974197595 0.7693467506480887 0.05072260040071561 59.238528894843725 163023.39469764478 0.013985680789633175 0.023739657109513673 1.7675103894060226e-06 5.752638024745521 0.20512451671126541 ADLTALFLPR ddPTM_PC-9_Lapatinib_30min_R1 1 ADLTALFLPR 10 0 Q13045-2;Q13045-3;Q13045 Q13045-2 FLII Protein flightless-1 homolog 0 89.029 0.04428 1406500.0 6694.3 6941.3 10136.0 7167.3 8926.6 7091.2 7799.8 5976.1 7836.7 6839.6 False True 6598.83805441573 6925.227846322206 9302.657206091479 7694.407151411897 8401.55493837085 6787.925906394571 8203.635479285498 6253.771422825648 6954.048321890545 8021.815746805864 0.8226115212186546 0.8632992909466539 1.1596697680067785 0.9591852261722247 1.0473383088755424 0.8461832234301062 1.0226656580278637 0.7795954956103027 0.8668920530441646 1.0 12.969713113913206 -7.750878686324862 24.999626718554055 0.8674328116255305 0.9630205627964671 0.09275058277506809 0.10860589897482598 417.7291142255712 988868.1615748744 0.052095008334131186 0.029670900565805097 1.7746851434399122e-08 7.750878686324862 0.09558775117093654 ADNPS(ph)PNLMPASAQAQNAQR ddPTM_PC-9_AZD4547_30min_R2 4 ADNPSPNLMPASAQAQNAQR 20 0 Q92585 Q92585 MAML1 Mastermind-like protein 1 1 ADNPS(1)PNLMPASAQAQNAQR;ADNPS(0.975)PNLMPAS(0.025)AQAQNAQR;ADNPS(1)PNLMPASAQAQNAQR;ADNPS(1)PNLMPASAQAQNAQR 221.9 2.4051999999999998e-29 18849100.0 67569.1 49857.9 74136.0 107906.0 94783.0 79566.0 72522.0 94958.0 81011.0 91075.0 True False 89054.66827541083 65973.49115062566 73152.90820039807 83029.93883108122 81624.01652367174 74590.72544196996 78976.31750627016 80284.42301776135 85293.07607276554 87886.49197107257 1.0132918754422782 0.7506670214159934 0.8323566746124764 0.9447406190522446 0.9287435952107169 0.8487166089928946 0.8986172474862787 0.9135012812229051 0.9704913025865154 1.0 16.423353821779273 -8.241000238826594 1.5541293750563856 1.0003999312573928 0.882025809040653 0.25247603912500194 0.06657911213031878 0.5205339745603492 2.367916404122577 0.06231575086191188 0.019032014665519913 5.741161464901193e-09 8.241000238826594 -0.11837412221673982 ADNPS(ph)PNLMPASAQAQNAQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ADNPSPNLMPASAQAQNAQR 20 0 Q92585 Q92585 MAML1 Mastermind-like protein 1 1 ADNPS(1)PNLMPASAQAQNAQR;ADNPS(0.998)PNLMPAS(0.002)AQAQNAQR;ADNPS(0.999)PNLMPAS(0.001)AQAQNAQR 155.53 1.746e-05 17285700.0 56085.0 52626.0 62293.0 60839.0 67242.0 64854.0 61206.0 61169.0 55994.0 45109.9 True False 65579.08277075698 57850.36148688234 63778.30136751808 57430.388072699265 54066.41280073584 61452.94207105801 55408.12458693372 59563.37856391279 56812.8063197594 53287.967780228086 1.2306546018271949 1.0856177087756589 1.1968612057144787 1.0777365034740203 1.0146082699891699 1.1532236005791057 1.039786782927239 1.1177641228422512 1.066146987516367 1.0 15.70152219427074 -1.5228787452803376 0.3616696822189379 1.0598418487194414 2.864575228159386 0.4252764931456535 0.05484406598439273 68.15396507930195 0.9497819853593423 0.04332658829615125 84.80474509692166 0.029999999999999995 1.5228787452803376 1.8047333794399445 ADNPS(ph)PNLMPASAQAQNAQR ddPTM_PC-9_Lapatinib_30min_R1 1 ADNPSPNLMPASAQAQNAQR 20 0 Q92585 Q92585 MAML1 Mastermind-like protein 1 1 ADNPS(0.63)PNLMPAS(0.37)AQAQNAQR 124.77 1.0124e-05 4413100.0 11301.0 12750.0 16682.0 9946.2 13741.0 8710.1 8604.4 9673.0 12181.0 10225.0 True False 11139.84566765041 12720.47815835766 15310.470354382203 10677.676727550544 12932.781395845423 8337.589327234795 9049.893730347456 10122.44289302262 10809.047508383466 11992.37762604391 0.9289105142468119 1.0607136095124732 1.2766834761050532 0.8903719562967879 1.078416790992241 0.6952407260031579 0.7546371547451736 0.8440730611284002 0.9013264796556607 1.0 13.549830097454466 -6.744654075680407 24.99684265538896 0.8240338990337897 1.05183661460892 0.4140239303615987 0.12299045010486963 227.4237647272496 338681.1127805942 0.040868214095086154 0.04076349694913306 1.800304322910106e-07 6.744654075680407 0.22780271557513032 ADNSSDS(ph)PTTLK ddPTM_PC-9_Lapatinib_30min_R1 1 ADNSSDSPTTLK 12 0 A0A2R8YH03;Q5VWN6;J3KPH3 A0A2R8YH03 FAM208B Protein FAM208B 1 ADNS(0.055)S(0.093)DS(0.809)PT(0.032)T(0.011)LK 73.758 0.021901 3759300.0 16926.0 20701.0 21949.0 16448.0 19870.0 17450.0 14023.0 17341.0 19449.0 15089.0 True False 16684.632136151748 20653.068106365638 20144.437945590154 17657.64078891954 18701.285665923057 16703.704177936776 14749.042324934035 18146.726166432898 17258.448812950508 17697.113545171313 0.9427883306260516 1.1670303212808883 1.1382894670462573 0.997769537040545 1.0567421414903977 0.943866022857406 0.833415137857797 1.025405986129544 0.9752126395583592 1.0 14.111226450950845 -6.534620541071715 2.0064918396140192 0.9506018742817994 1.077673578922965 0.29860076248137646 0.07722874100489184 0.38631966612125895 3.1374145667076014 0.029226850445635073 0.031377697690155776 2.919977190315534e-07 6.534620541071715 0.12707170464116557 ADPEAAWEPTEAEAR ddPTM_PC-9_Lapatinib_30min_R1 1 ADPEAAWEPTEAEAR 15 0 K7EPL2;Q9UBT2-2;Q9UBT2 K7EPL2 UBA2 SUMO-activating enzyme subunit 2 0 173.72 0.00034439 1178100.0 3189.7 2974.7 4763.6 4022.0 3529.6 4132.8 5047.6 3494.0 6085.0 4003.8 False True 3144.214293080658 2967.8122649150223 4371.9551960277595 4317.791296998684 3321.995867460594 3956.0497780273436 5308.940029903516 3656.3439954741093 5399.643222109301 4695.851495271848 0.6695727699750514 0.6320072659672583 0.9310250122751512 0.9194905974659069 0.7074320537618024 0.8424563217151576 1.1305596088907355 0.7786327994306471 1.149875209543165 1.0 12.197171069084805 -3.558919211913856 0.25700524375803707 1.0347138199528483 2.0796180814480612e-14 0.43626749709545254 0.13032073270342032 18.159384652006025 0.6112826585323934 0.17205329797928492 6.621135036805973 0.0002761091430662698 3.558919211913856 -1.0347138199528274 ADPPY(ph)THTIQK ddPTM_PC-9_AZD4547_30min_R2 1 ADPPYTHTIQK 11 0 A0A2R8YE63;Q12929;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 ADPPY(0.802)T(0.198)HTIQK 75.416 0.037837 4223100.0 40665.0 46258.0 51210.0 88040.0 76581.0 59303.0 51539.0 80611.0 71517.0 64135.0 True False 53595.624115454855 61209.99387550705 50530.921939980435 67743.73820444077 65949.05003428172 55594.774035205155 56125.871155727305 68154.42220649935 75297.24261515087 61889.653171174694 0.8659868228251308 0.9890182080389457 0.8164680096077089 1.0945890748018061 1.065590880787125 0.8982886667895984 0.9068700223685873 1.1012248205366013 1.216637010501471 1.0 15.917410616673088 -7.827711774141424 6.538421501998691 1.122598899510459 0.95301865770718 0.3653876119241135 0.09459552026643368 0.22645426244686687 17.297667678342425 0.05264439362202569 0.02515606023929371 1.4869221324322862e-08 7.827711774141424 -0.16958024180327902 ADPSLLGFSVNAS(ph)SER ddPTM_PC-9_AZD4547_30min_R2 2 ADPSLLGFSVNASSER 16 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 ADPSLLGFSVNAS(0.881)S(0.119)ER;ADPSLLGFS(0.005)VNAS(0.768)S(0.227)ER 145.04 2.9505e-05 12470800.0 8072.400000000001 10423.599999999999 17421.0 22156.9 20532.9 14769.0 15170.599999999999 20406.3 18313.5 14098.8 True False 10639.255283649276 13792.82485539225 17189.986157320807 17048.969025692575 17682.261258652954 13845.49209527251 16520.754010653625 17252.975225124213 19281.514222248745 13605.205303340725 0.7819988781085746 1.0137902771673322 1.2634859801123213 1.2531210404819282 1.2996688300110486 1.0176613866953395 1.2142965609344385 1.2681157572012374 1.4172159693550685 1.0 13.731871106653525 -4.94689667135873 2.5493304754525887 1.2231480591066861 0.7581481528666582 0.5687985476462847 0.11916309214086022 0.2547399986633327 2.756426982391675 0.03130049340004905 0.2214270940984124 1.1300647510737647e-05 4.94689667135873 -0.46499990624002796 ADPSLLGFSVNAS(ph)SER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ADPSLLGFSVNASSER 16 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 ADPSLLGFS(0.047)VNAS(0.672)S(0.281)ER;ADPSLLGFSVNAS(0.771)S(0.229)ER;ADPSLLGFS(0.107)VNAS(0.659)S(0.234)ER;ADPSLLGFS(0.01)VNAS(0.758)S(0.233)ER 181.69 2.2305e-06 22953500.0 34596.899999999994 27119.700000000004 50067.0 52716.0 60122.0 53950.7 54701.0 50146.4 43189.7 39234.3 True False 40453.471850077585 29811.96458814664 51260.78716015484 49762.49342757795 48341.525689388225 51121.430317220635 49519.325279055374 48830.1101345027 43821.26765561511 46347.1680114521 0.8728358945271862 0.6432316335008923 1.1060176783075206 1.0736900562140483 1.043030842303964 1.1030108744635452 1.0684433893958625 1.053572682638065 0.945500438015698 1.0 15.500193566929767 -5.268956296227966 24.99994966577533 1.0543409249786737 0.7580337591954694 0.7427213936455117 0.06848306361829914 224.19173787017849 745624.1587756159 0.01692584664494274 0.03634755690656672 5.383239522203453e-06 5.268956296227966 -0.29630716578320426 ADPSLLGFSVNAS(ph)SER ddPTM_PC-9_Lapatinib_30min_R1 3 ADPSLLGFSVNASSER 16 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 ADPSLLGFSVNAS(0.933)S(0.067)ER;ADPSLLGFSVNAS(0.767)S(0.233)ER;ADPSLLGFSVNAS(0.897)S(0.103)ER 195.17 8.6185e-12 16131900.0 27254.7 22819.1 29371.2 22215.3 27785.2 23144.2 22108.0 23116.2 30329.1 22499.0 True False 26866.042980100163 22766.26377595132 26956.413312110693 23849.087270068325 26150.929163804976 22154.376517765293 23252.644064725213 24190.263041837043 26913.11737841827 26387.922171966955 1.0181189259623153 0.862753180321902 1.021543611370344 0.9037879949261126 0.9910188833126942 0.839565024232975 0.8811851085959135 0.9167172346572788 1.0199028632504172 1.0 14.687590134525234 -8.261493170971763 24.999747896949096 1.0099514394900202 0.9267974553852498 0.2229464805053485 0.0600513100050992 6.920107389409485 3211712.452846272 0.04562917082293879 0.014730337737067752 5.476547124461457e-09 8.261493170971763 -0.08315398410477037 ADPSLLGFSVNASS(ph)ER ddPTM_PC-9_Lapatinib_30min_R1 1 ADPSLLGFSVNASSER 16 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 ADPSLLGFSVNAS(0.337)S(0.663)ER 167.14 4.5778999999999997e-05 8053200.0 16397.0 13706.0 16883.0 15590.0 17020.0 16176.0 14561.0 13299.0 17956.0 11456.0 True False 16163.175773158471 13674.264599094126 15494.944910264643 16736.540606715433 16018.917062607461 15484.190188097733 15314.897332479812 13916.920090386417 15933.606194937478 13436.154335839521 1.2029614552762995 1.0177216082297798 1.1532276664114758 1.2456347395528555 1.192224848138183 1.152427234837225 1.1398274349699111 1.035781499864474 1.1858754965649858 1.0 13.71383265200225 -10.801697210737274 5.386603005243411 0.9999811540070495 1.144526205398222 0.29868366323012263 0.06759258501094495 1.5809452955741583e-05 2.116508156282982e-06 0.06763277031523078 0.016401218615580568 1.5787115607044784e-11 10.801697210737274 0.14454505139117246 ADQEEQIHPR ddPTM_PC-9_Lapatinib_30min_R1 1 ADQEEQIHPR 10 0 Q9UHB6;Q9UHB6-4;F8VRN8;F8VTU2 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 0 112.83 0.0014263 0.0 29714.0 28845.0 30399.0 34994.0 30199.0 27670.0 26689.0 25770.0 29780.0 22121.0 False True 29290.272911119777 28778.21117473151 27899.71156353345 37567.57549656188 28422.754193518384 26486.618601920385 28070.825829720045 26967.368278010246 26425.862802697608 25944.585375620278 1.1289551359970236 1.1092183882720263 1.0753577734855757 1.4479929030534266 1.0955177653456278 1.020891959476425 1.0819531483473912 1.0394218249234795 1.0185502069163757 1.0 14.663145859680641 -6.513947077007909 24.97755798274011 1.0400130941989334 1.1882912092548257 0.3701977873403417 0.09703548322994822 512.5372340987448 1433324.1088590552 0.03220286629271834 0.03386462554680555 3.06233658634933e-07 6.513947077007909 0.14827811505589228 ADQEQQDPLEY(ph)LQSDEEDDEKR ddPTM_PC-9_AZD4547_30min_R2 1 ADQEQQDPLEYLQSDEEDDEKR 22 1 Q7RTV3 Q7RTV3 ZNF367 Zinc finger protein 367 1 ADQEQQDPLEY(0.915)LQS(0.085)DEEDDEKR 88.98299999999999 0.0014309000000000001 1989400.0 4705.7 3383.2 4416.1 4732.3 5773.9 4911.6 5019.0 4052.6 3672.5 5541.5 True False 6202.014715359549 4476.753237918099 4357.53962857152 3641.3413483061686 4972.2936497687315 4604.476875559646 5465.681276908662 3426.3637894835633 3866.6208524426534 5347.493771701328 1.159798399051964 0.83716848098241 0.8148751199358854 0.6809435417346283 0.9298362676141603 0.8610532470231773 1.0221014759910103 0.6407419878851867 0.7230715953152894 1.0 12.384647181726864 -4.761479737711205 6.3319442041813 0.8268085520042713 1.170068219023097 0.3926818590665121 0.12112938318060806 0.12968552472973968 22.881011961361544 0.030361493882415352 0.19250510239612065 1.731889831300841e-05 4.761479737711205 0.3432596670188258 ADQEQQDPLEYLQS(ph)DEEDDEKR ddPTM_PC-9_AZD4547_30min_R2 2 ADQEQQDPLEYLQSDEEDDEKR 22 1 Q7RTV3 Q7RTV3 ZNF367 Zinc finger protein 367 1 ADQEQQDPLEY(0.039)LQS(0.961)DEEDDEKR;ADQEQQDPLEYLQS(1)DEEDDEKR 103.59 0.00092081 2050500.0 6223.4 2300.6 5570.9 5581.299999999999 4898.7 5400.0 5430.4 5952.5 5652.6 5490.1 True False 8202.311745238456 3044.223959314962 5497.026226038601 4294.617515225411 4218.600062717068 5062.3371463519225 5913.695079921257 5032.677899842297 5951.384895988383 5297.8932700563855 1.548221401816039 0.5746102845296772 1.0375871966141168 0.810627412880989 0.7962787937915875 0.955537774791383 1.1162352237908177 0.9499394652374215 1.1233493376745662 1.0 12.371203064513193 -7.019805432094414 22.03737183025422 1.0421632782972523 0.9238308750454421 0.02786610898510755 0.24004258201786566 566.2078005356831 630012.8685310644 0.08546770655054424 0.06737592407749618 9.554205273003769e-08 7.019805432094414 -0.11833240325181016 ADQEQQDPLEYLQS(ph)DEEDDEKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADQEQQDPLEYLQSDEEDDEKR 22 1 Q7RTV3 Q7RTV3 ZNF367 Zinc finger protein 367 1 ADQEQQDPLEY(0.326)LQS(0.674)DEEDDEKR 65.744 0.0013264000000000001 2353000.0 5986.1 7602.6 10142.0 7954.0 6874.4 6942.4 8601.4 8587.7 6750.5 5194.3 True False 6999.42849913575 8357.33588416699 10383.823743749186 7508.363167215927 5527.410668293308 6578.328322603281 7786.613123256733 8362.281974420275 6849.21329180869 6135.985471943827 1.1407179060543622 1.3620201550965307 1.6922829741413452 1.2236605190066303 0.9008187345890621 1.072089944261117 1.2690077508918876 1.3628262342953652 1.1162368820992201 1.0 12.58307935166535 -5.987297940410199 24.88879830872047 1.1359700589884185 1.4052522842719948 0.33685296987890967 0.17368099854545593 271.5888058892593 532154.3306966997 0.05192902186249678 0.07696939505571779 1.0296794838244405e-06 5.987297940410199 0.26928222528357626 ADQEQQDPLEYLQS(ph)DEEDDEKR ddPTM_PC-9_Lapatinib_30min_R1 1 ADQEQQDPLEYLQSDEEDDEKR 22 1 Q7RTV3 Q7RTV3 ZNF367 Zinc finger protein 367 1 ADQEQQDPLEY(0.486)LQS(0.514)DEEDDEKR 88.27799999999999 9.813700000000001e-05 1967800.0 2351.2 2352.5 3026.6 2475.2 2276.1 1056.5 2412.3 2947.8 2546.1 2257.0 True False 2317.6714568427274 2347.05293078717 2777.7646310138593 2657.234465025148 2142.2242729847744 1011.3159578217889 2537.1970905254475 3084.7655494729747 2259.3314063783873 2647.1194427365394 0.8755447220948839 0.8866441358463347 1.0493537186755206 1.0038211431359334 0.8092661926770428 0.38204394614559234 0.9584747290067666 1.1653291875201541 0.853505652182712 1.0 11.370207577929829 -9.983178433480099 8.66253703178343 1.0000009690761884 0.8884377451430034 0.028900320420029657 0.19618201793762882 0.0 0.0 0.2050645082113926 0.04973544867181835 1.0394929937869604e-10 9.983178433480099 -0.11156322393318496 ADRDESSPYAAMLAAQDVAQR ddPTM_PC-9_Lapatinib_30min_R1 1 ADRDESSPYAAMLAAQDVAQR 21 1 P62263;A0A2R8Y811;E5RH77 P62263 RPS14 40S ribosomal protein S14 0 60.56100000000001 0.012745999999999999 4549700.0 21483.0 19007.0 26772.0 20923.0 18158.0 20704.0 14755.0 15119.0 21497.0 15261.0 False True 21176.648480500302 18962.990459286604 24570.909502908555 22461.747217081902 17089.98214000154 19818.53818338127 15518.941703230534 15821.483934623084 19075.781486554413 17898.84351599572 1.1831294274166537 1.0594533910718804 1.372765200218114 1.2549272916436438 0.9548092939484429 1.1072524415150047 0.8670360009216054 0.8839388936209116 1.065754972912462 1.0 14.127578754321778 -6.263972148220263 24.984750826148943 0.9747301002694252 1.2173603282841636 0.5793780166404363 0.09919298424284653 167.38070162821774 1651141.6148400975 0.03156940326832205 0.0374788623103515 5.445375735123389e-07 6.263972148220263 0.24263022801473844 ADRDQS(ph)PFSK ddPTM_PC-9_AZD4547_30min_R2 4 ADRDQSPFSK 10 1 Q13427;E9PG73 Q13427 PPIG Peptidyl-prolyl cis-trans isomerase G 1 ADRDQS(0.999)PFS(0.001)K;ADRDQS(0.998)PFS(0.002)K;ADRDQS(0.927)PFS(0.073)K;ADRDQS(0.997)PFS(0.003)K 108.32 0.009866799999999998 224948000.0 301768.0 278612.0 368196.0 426631.0 397609.0 394563.0 340106.0 374069.0 315368.0 352125.0 True False 397723.946835672 368667.8804453881 363313.4804650073 328277.81433324347 342407.8535809242 369890.9132363056 370374.7751273745 316265.2313004798 332037.70864346775 339797.2109285084 1.1704744301722687 1.0849644099137528 1.069206776218792 0.9660992020393937 1.0076829431450662 1.0885637119432647 1.089987684464248 0.9307469900540779 0.9771643143749252 1.0 18.374314485298783 -4.862220751709263 1.2667712869357537 1.0130364429305254 1.2224881352386552 0.5112003754217331 0.04880144182941524 1.14378406408362 1.7716989107194134 0.01619429699832784 0.3025057912168284 1.3733437275075977e-05 4.862220751709263 0.20945169230812977 ADRDQS(ph)PFSK ddPTM_PC-9_Lapatinib_30min_R1 1 ADRDQSPFSK 10 1 Q13427;E9PG73 Q13427 PPIG Peptidyl-prolyl cis-trans isomerase G 1 ADRDQS(0.984)PFS(0.016)K 115.92 0.0052307 12554000.0 40115.0 43116.0 46565.0 42419.0 44026.0 43501.0 39935.0 41030.0 40367.0 40406.0 True False 39542.95274380998 43016.16755103916 42736.60544609804 45538.63476563577 41436.47723844629 41640.56363578387 42002.6388965443 42936.403587379114 35820.44337664523 47390.12326238929 0.834413376071399 0.907703221468059 0.901804057555924 0.9609309204261358 0.8743694758720316 0.8786759934180526 0.8863163040109517 0.9060200867098225 0.7558630556480063 1.0 15.532298792995306 ADREVQAEQPSS(ph)SSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADREVQAEQPSSSSPR 16 1 Q9Y388;A0A1W2PP04 Q9Y388 RBMX2 RNA-binding motif protein, X-linked 2 1 ADREVQAEQPS(0.018)S(0.486)S(0.486)S(0.01)PR 114.01 0.00096665 9633600.0 13539.0 9983.0 15073.0 21633.0 23402.0 22729.0 16923.0 23130.0 20049.0 20118.0 True False 15830.885292560908 10974.046264651442 15432.397484670817 20420.973145132284 18816.54609266263 21537.05122788228 15319.93092809005 22522.862008260767 20342.178696018436 23765.234145999613 0.6661363063079987 0.46176890988043123 0.6493686277132069 0.859279274072279 0.791767755245534 0.906241911843633 0.6446362292907956 0.9477231265593075 0.8559637397657461 1.0 14.536564995353737 -3.9916350178558013 0.23121744862837548 0.9768414763221724 3.4178199064161795e-14 0.555633212361696 0.10629359732840331 12.517291631805376 0.4334053814967746 0.1713493139089652 3.7047720990133763 0.00010194477745507728 3.9916350178558013 -0.9768414763221382 ADREVQAEQPSS(ph)SSPR ddPTM_PC-9_Lapatinib_30min_R1 1 ADREVQAEQPSSSSPR 16 1 Q9Y388;A0A1W2PP04 Q9Y388 RBMX2 RNA-binding motif protein, X-linked 2 1 ADREVQAEQPS(0.106)S(0.298)S(0.298)S(0.298)PR 63.31 0.016013 10423000.0 42332.0 28963.0 31016.0 22746.0 26603.0 23420.0 22497.0 18374.0 27328.0 17361.0 True False 41728.337917261946 28895.93795298142 28465.984205222318 24418.816718431633 25038.26384351037 22418.381194686503 23661.78458133359 19227.723117584803 24250.032863402295 20361.8257179216 2.049341669815711 1.419123135286855 1.3980074576597414 1.1992449526242257 1.229666936077975 1.10100054411893 1.1620659615265987 0.9443025092126877 1.1909557227011556 1.0 14.313579304229409 -1.5228787452807655 0.5790513160895279 1.0844753005994066 51.41472128509538 0.9073625366485288 0.0901895673477703 40.021378301366326 0.33330227490588815 0.03981524221785171 2531.6826472044277 0.02999999999997044 1.5228787452807655 50.330245984495974 up ADREVQAEQPSSS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 3 ADREVQAEQPSSSSPR 16 1 Q9Y388;A0A1W2PP04 Q9Y388 RBMX2 RNA-binding motif protein, X-linked 2 1 ADREVQAEQPS(0.005)S(0.034)S(0.484)S(0.478)PR;ADREVQAEQPS(0.092)S(0.092)S(0.408)S(0.408)PR;ADREVQAEQPS(0.004)S(0.022)S(0.487)S(0.487)PR 80.596 0.003743 79308000.0 32002.4 33264.3 48882.0 85822.0 62314.0 40005.0 40696.0 46749.0 35270.0 39722.0 True False 42178.497508728215 44016.33445615954 48233.7927410686 66037.06383668237 53662.77671793561 37503.48102589049 44317.86516140164 39525.016235149546 37134.3001948679 38331.344870435816 1.1003657098725912 1.1483117695176002 1.258338127819521 1.7227953796010798 1.3999711437029336 0.9784024315519427 1.1561781959699282 1.0311408683610885 0.9687711276602984 1.0 15.226236996103507 -6.762265668954872 24.999999945230133 1.0369247859195487 1.3343773331455362 0.4483736757731198 0.16553641830356466 24.10994810438382 729446.7990020959 0.06332845324271627 0.05912516365294159 1.7287585102433204e-07 6.762265668954872 0.29745254722598746 ADREVQAEQPSSS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ADREVQAEQPSSSSPR 16 1 Q9Y388;A0A1W2PP04 Q9Y388 RBMX2 RNA-binding motif protein, X-linked 2 1 ADREVQAEQPS(0.014)S(0.225)S(0.38)S(0.38)PR;ADREVQAEQPS(0.007)S(0.135)S(0.429)S(0.429)PR;ADREVQAEQPS(0.003)S(0.067)S(0.465)S(0.465)PR;ADREVQAEQPS(0.001)S(0.012)S(0.494)S(0.494)PR 125.61 0.00015035 39112000.0 56266.7 60467.7 79080.9 81639.0 112917.8 101619.8 89234.0 89029.1 86055.0 78281.0 True False 65791.54099201827 66470.53363889262 80966.48857198331 77065.03150720928 90792.3676772095 96290.67879656624 80781.10952178627 86692.18045912874 87313.39157493475 92472.72562794482 0.7114696851991176 0.7188123112790086 0.8755715593130049 0.8333812049325017 0.9818286101190953 1.0412873432971208 0.8735668703743129 0.9374891879788041 0.9442069646160517 1.0 16.496740292166784 -5.47121881215153 1.1388172090091795 0.9566625707376283 0.6825028272132139 0.767306299770835 0.051378958970577975 0.3298263915506308 0.7143785091734918 0.01824979051869994 0.08171839327636973 3.378945506844898e-06 5.47121881215153 -0.2741597435244144 ADREVQAEQPSSS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 ADREVQAEQPSSSSPR 16 1 Q9Y388;A0A1W2PP04 Q9Y388 RBMX2 RNA-binding motif protein, X-linked 2 1 ADREVQAEQPS(0.004)S(0.03)S(0.483)S(0.483)PR 76.01 0.0055834 25873000.0 17254.0 7738.4 15822.0 8593.6 10927.0 12012.0 6609.3 3074.9 15476.0 6562.6 True False 17007.954796003927 7720.482210245879 14521.176234686207 9225.602011409224 10284.295343308557 11498.27476133963 6951.497214446734 3217.771079474338 13732.929910495239 7696.936665885167 2.20970439725555 1.00305907991488 1.8866176071121712 1.198606979878047 1.3361543416215491 1.4938767538913222 0.9031511517117693 0.41805866660386326 1.784207212118968 1.0 12.910068660823141 -1.522878745280759 0.3140020192412413 1.0171313037177914 9.281441191926637 0.2758681630883769 0.43083669964794874 76.70418776820189 1.0952614825995537 0.4062851590114869 361.67092579845786 0.029999999999970883 1.522878745280759 8.264309888208846 ADREVQAEQPSSSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 ADREVQAEQPSSSSPR 16 1 Q9Y388;A0A1W2PP04 Q9Y388 RBMX2 RNA-binding motif protein, X-linked 2 1 ADREVQAEQPS(0.011)S(0.036)S(0.14)S(0.813)PR 142.4 0.00012677 9250800.0 22098.0 17897.0 32565.0 49489.0 38095.0 32080.0 25113.0 33251.0 26596.0 32484.0 True False 29124.704333046157 23681.855255089926 32133.16682240698 38080.0756474281 32806.16681756521 30074.032528698095 27348.008349672666 28112.82198196662 28001.81026318986 31346.74504736008 0.9291141485038793 0.7554805202042607 1.0250878288593837 1.2148015875299014 1.0465573624310966 0.959398893992371 0.8724353456269242 0.8968338479638794 0.8932924366113119 1.0 14.936028025197885 -7.0200942983208785 8.028036580333321 0.9081318876151958 0.9957614800887726 0.09828227174843673 0.11120220971915994 0.5375940625655694 175.7964980469396 0.04697660886071034 0.03789537953139131 9.54785251079264e-08 7.0200942983208785 0.08762959247357682 ADREVQAEQPSSSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ADREVQAEQPSSSSPR 16 1 Q9Y388;A0A1W2PP04 Q9Y388 RBMX2 RNA-binding motif protein, X-linked 2 1 ADREVQAEQPS(0.026)S(0.036)S(0.212)S(0.727)PR;ADREVQAEQPSS(0.002)S(0.231)S(0.767)PR;ADREVQAEQPS(0.007)S(0.007)S(0.174)S(0.813)PR 112.91 0.00083264 34531100.0 55018.6 32351.0 54497.0 55421.2 73709.0 64000.0 54358.5 69496.0 60986.0 44204.4 True False 64332.16231311701 35562.59347968934 55796.41516102342 52316.12984195471 59266.25057448382 60643.72733443907 49209.269358540645 67671.80363709849 61877.80487582327 52218.30779816211 1.2319848157810518 0.6810368811097516 1.068522085715448 1.0018733284918138 1.1349707233632296 1.161349915222138 0.9423757956452321 1.2959401882318424 1.1849829587545757 1.0 15.672268085557988 -6.021861762101912 1.8878466567725467 1.128633907146795 0.9578910312879286 0.11874860819604671 0.15713840210080912 0.5988274168705802 4.27726265958326 0.049698155744032003 0.07880495855577663 9.509074236237804e-07 6.021861762101912 -0.17074287585886638 ADREVQAEQPSSSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 ADREVQAEQPSSSSPR 16 1 Q9Y388;A0A1W2PP04 Q9Y388 RBMX2 RNA-binding motif protein, X-linked 2 1 ADREVQAEQPSSS(0.029)S(0.971)PR;ADREVQAEQPS(0.001)S(0.016)S(0.246)S(0.737)PR 191.36 7.2096e-08 6488200.0 76520.0 58318.0 70342.0 58538.1 66132.0 63003.2 54714.8 56894.6 75607.0 51411.8 True False 75428.81076795074 58182.96825404723 64558.75228797218 62843.18715137705 62242.24578051451 60308.70000363245 57547.66462242752 59538.130819948856 67091.34348299383 60298.2611280826 1.2509284572523338 0.964919504568429 1.0706569489763502 1.0422056287475463 1.0322394811403033 1.0001731206730435 0.9543834854571941 0.987393827053833 1.1126580141420943 1.0 15.879828778058494 -4.753350389503626 24.999819130922884 1.0181544521894672 1.2509288829821867 0.6991008337241543 0.04578659601936319 170.83261894538296 527933.5091936586 0.01148860043686363 0.12511029371295426 1.7646135530903537e-05 4.753350389503626 0.23277443079271953 ADRS(ph)PSLSVAPQDR ddPTM_PC-9_Lapatinib_30min_R1 2 ADRSPSLSVAPQDR 14 1 A0A2R8YH03;Q5VWN6;Q5VWN6-2 A0A2R8YH03 FAM208B Protein FAM208B 1 ADRS(0.988)PS(0.01)LS(0.001)VAPQDR;ADRS(0.997)PS(0.003)LSVAPQDR 64.374 0.019525999999999998 9702100.0 20911.4 20660.9 27818.0 12865.6 20755.4 24400.0 16369.3 18977.4 23713.0 16457.0 True False 20613.19960131891 20613.06095545192 25530.911420585304 13811.779142383451 19534.60817868643 23356.468879178068 17216.822258399963 19859.159284404806 21042.19223103991 19301.570522425896 1.0679545261547019 1.0679473430155462 1.3227375145935265 0.7155779953934823 1.0120735074894436 1.2100812652546025 0.8919907444006316 1.0288882586694728 1.0901803149433689 1.0 14.236430620448619 -5.729231462507176 24.99989237698745 0.9995581233709261 1.1443862166547456 0.21988089208557537 0.1375715008613021 338.9456486971423 263088.3055464485 0.03750797217056595 0.06495906203819037 1.8653852461847138e-06 5.729231462507176 0.14482809328381951 ADS(ph)IGSGR ddPTM_PC-9_Lapatinib_30min_R1 1 ADSIGSGR 8 0 E7EUN2;A0A087X1U1;F5GXM9;Q9UPQ3-2;Q9UPQ3;A0A087X044;Q9UPQ3-3 E7EUN2 AGAP1 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 1 ADS(0.992)IGS(0.008)GR 67.704 0.045598 4621700.0 52637.0 50712.0 56066.0 68169.0 55416.0 45442.0 48462.0 49199.0 56584.0 74738.0 True False 51886.386727556404 50594.579479736 51456.469901018645 73182.3756651177 52156.5398320479 43498.55159047584 50971.12523361284 51484.96514977981 50210.91406406456 87656.363717875 0.5919294906477585 0.5771923147824883 0.5870249200232974 0.8348780688719608 0.5950114471998348 0.49623951696738655 0.5814880183447393 0.5873499990883255 0.5728153888024615 1.0 16.419571211788707 -11.012743484157522 2.8380380778938785 1.0141244411857602 0.6038521088480799 0.6766236291437937 0.08240353242530132 23626747.473666247 25717002.705002647 2607984.1850162377 0.02298283252407983 9.710833678485091e-12 11.012743484157522 -0.41027233233768023 ADS(ph)LLAVVK ddPTM_PC-9_AZD4547_30min_R2 2 ADSLLAVVK 9 0 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 1 ADS(1)LLAVVK;ADS(1)LLAVVK 81.017 0.022097 2905500.0 31504.0 35634.0 41842.0 59071.0 47595.0 40602.0 34411.0 39683.0 36958.0 48590.0 True False 41521.616676092206 47151.99363915035 41287.14774092289 45453.09358785237 40987.255799501676 38063.15052151496 37473.51233705994 33550.90417462274 38911.52442874763 46888.87888964493 0.8855322980490786 1.005611453200335 0.8805317746686594 0.9693789799246053 0.8741359736061723 0.8117735254685504 0.7991983008434798 0.7155407629511954 0.8298668117087559 1.0 15.516958164266413 -6.551825837124835 3.2154319643706226 0.8115592913396057 0.9361840811014616 0.2775546900651712 0.07549668205889903 0.26211248735970033 5.6166918560109025 0.0246181669617665 0.02568876617377701 2.806558912144176e-07 6.551825837124835 0.12462478976185587 ADS(ph)LLAVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ADSLLAVVK 9 0 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 1 ADS(1)LLAVVK;ADS(1)LLAVVK 95.48299999999999 0.005411600000000001 3658000.0 40961.0 45680.0 44597.0 48125.0 58637.0 44805.0 53355.0 39825.0 33746.0 33726.0 True False 47894.888283373024 50214.80851139717 45660.36161506432 45428.71227335512 47147.50077922651 42455.346925305355 48300.82814325148 38779.63594807544 34239.47140884026 39840.25682513092 1.2021731811016165 1.2604037351416386 1.1460860258878183 1.1402715718614307 1.1834135755240975 1.0656393886126974 1.2123623689288994 0.9733781616491375 0.8594189429833764 1.0 15.281939327134873 -7.847643051223533 4.98622448819114 0.9268930834560148 1.170115854310492 0.7641549683779433 0.05835842425456802 0.09679539001894039 4.083146564761512 0.03333895143293982 0.015616528033065508 1.4202243315021577e-08 7.847643051223533 0.24322277085447708 ADS(ph)LLAVVK ddPTM_PC-9_Lapatinib_30min_R1 2 ADSLLAVVK 9 0 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 1 ADS(1)LLAVVK;ADS(1)LLAVVK 111.86 0.0016254000000000002 2491000.0 47146.0 43479.0 49387.0 40041.0 40701.0 46729.0 46274.0 43360.0 49321.0 39025.0 True False 46473.68939448247 43378.32704684178 45326.59149933303 42985.74871286033 38307.04720124478 44730.509600619385 48669.84129957911 45374.66389346233 43765.94960684513 45770.41925245613 1.0153651671431565 0.9477371576515331 0.990303174837113 0.9391600386215303 0.836938962476057 0.9772798748881694 1.0633470720713878 0.9913534687805474 0.95620600207844 1.0 15.482127886490627 -6.996583627239187 24.99596711517634 1.004621440963648 0.9439966416801436 0.22496279425048116 0.049725892228474664 156.4313388855409 1144521.9093714398 0.018516975375704896 0.01625086353435957 1.0078975111073752e-07 6.996583627239187 -0.060624799283504394 ADS(ph)PAGPESSR ddPTM_PC-9_AZD4547_30min_R2 1 ADSPAGPESSR 11 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 ADS(0.999)PAGPES(0.001)SR 69.229 0.035238 3841100.0 11342.0 13337.0 22527.0 19555.0 23262.0 19140.0 17744.0 20507.0 17121.0 18863.0 True False 14948.520071744488 17647.924430750074 22228.277261119674 15046.89687173829 20032.472831347997 17943.172774291823 19323.18162531724 17338.114353980003 18025.981106785755 18202.61211145036 0.8212293917058814 0.9695270284669002 1.221158651572703 0.8266339347127567 1.100527369846362 0.9857471369729768 1.0615609181257006 0.9525069395437733 0.9902963924307604 1.0 14.151857874469602 -4.813094681918922 4.403949288076049 1.0168005796158317 0.813420354416273 0.2682556278067778 0.09670469351912409 0.2381672651792621 8.665850615704619 0.0227403395726093 0.13415758399838015 1.5378193388775223e-05 4.813094681918922 -0.20338022519955867 ADS(ph)PAGPESSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADSPAGPESSR 11 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 ADS(0.999)PAGPESS(0.001)R 85.973 0.011170999999999999 4302500.0 13959.0 16112.0 14324.0 14936.0 16664.0 12459.0 13544.0 11504.0 11717.0 10003.0 True False 16321.982997182797 17711.492879501548 14665.538484072511 14099.184343165345 13398.808823524912 11805.628107184002 12261.014269931551 11202.032189495536 11888.338958613806 11816.464716295564 1.3812915613139243 1.4988825596099322 1.2411105043835924 1.1931812671282116 1.1339101114605967 0.9990829229069996 1.0376211975670633 0.9480020004669678 1.0060825504111328 1.0 13.528510849992218 -5.824851894079507 0.8030718850117765 0.9845901162494332 1.4877818959139464 0.9174433700261971 0.050153921682726955 0.20566057446796124 0.24398090048563445 0.022804152981540864 0.07157686445415959 1.4967459990958245e-06 5.824851894079507 0.5031917796645132 ADS(ph)PAGPESSR ddPTM_PC-9_Lapatinib_30min_R1 1 ADSPAGPESSR 11 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 ADS(1)PAGPESSR 81.709 0.014755 4338900.0 11018.0 14632.0 14505.0 13871.0 13404.0 13139.0 13360.0 12019.0 15532.0 12400.0 True False 10860.881299546261 14598.12050298739 13312.454890919184 14891.119612299544 12615.603073277929 12577.075598504945 14051.715429017957 12577.446617516689 13782.622600789093 14543.323478038592 0.7467950029404854 1.0037678474959004 0.9153653847431708 1.0239144879632327 0.8674498021259273 0.8648006501056781 0.9661969941215296 0.8648261614004178 0.9476941513129231 1.0 13.828069374899593 -8.530816451942448 22.304537477324306 1.0000000069411565 0.9129176374370515 0.12546666361427172 0.07596764521596885 496.3198626387218 1394638.7457096416 0.06961199559076241 0.017973739990570215 2.9456663125021673e-09 8.530816451942448 -0.08708236950410508 ADS(ph)PAGPESSRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ADSPAGPESSRR 12 1 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 ADS(1)PAGPESSRR;ADS(1)PAGPESSRR 63.211999999999996 0.022216999999999997 6943800.0 12533.599999999999 11557.099999999999 17265.3 17433.2 21046.1 18874.6 17365.2 19997.0 19632.1 17512.6 True False 14655.290930116069 12704.412509786955 17676.97023101488 16456.474323196973 16922.267785692966 17884.782749165675 15720.242542839298 19472.099938572883 19919.182322215755 20687.495750334678 0.7084130001515035 0.6141107006429923 0.8544760779336428 0.7954792847718528 0.8179949854693844 0.8645213980950952 0.7598910343019638 0.9412497372118067 0.9628609746974091 1.0 14.336471395108134 -2.8160250005054865 0.14429550383402 1.059954938803209 1.1255173625406905e-18 0.6986165765923258 0.062189471123607266 28.508246595314812 0.3856826307740494 0.276707750949594 5.906826397711591 0.0015274781252202338 2.8160250005054865 -1.059954938803209 ADS(ph)PAGPESSRR ddPTM_PC-9_Lapatinib_30min_R1 1 ADSPAGPESSRR 12 1 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 ADS(0.969)PAGPES(0.006)S(0.025)RR 73.848 0.030304 0.0 6327.9 6076.3 8904.2 4576.1 4796.0 4629.3 4080.5 5702.4 6074.6 3702.3 True False 6237.662985605264 6062.230700676761 8172.131047205971 4912.641659422096 4513.9087092987875 4431.3156304253735 4291.76832396016 5967.3543216346725 5390.414579626156 4342.237621995345 1.4365088990083719 1.3961075437163766 1.8820091755942905 1.1313617740626178 1.0395351664850982 1.0205143099444418 0.988377122021251 1.3742578921538968 1.2413909714017801 1.0 12.084222961949573 -5.849958780567911 10.675400225801104 1.116130109636825 1.5536091799728684 0.6162761132598229 0.16541329350899853 0.2678805949168111 30.251671856643075 0.04847175334405471 0.07196554547403392 1.4126716166889764e-06 5.849958780567911 0.4374790703360434 ADS(ph)PVHMEQQSR ddPTM_PC-9_AZD4547_30min_R2 1 ADSPVHMEQQSR 12 0 O95402 O95402 MED26 Mediator of RNA polymerase II transcription subunit 26 1 ADS(1)PVHMEQQSR 90.861 0.0059161000000000005 2526000.0 8654.6 9611.7 10342.0 11886.0 10783.0 12623.0 9195.3 12573.0 10416.0 10023.0 True False 11406.582773136997 12718.494057962103 10204.858322657245 9145.866336869407 9285.966578128508 11833.681814518573 10013.66388634353 10630.13174879752 10966.568495314543 9672.09782076376 1.1793287231493563 1.314967475893227 1.0550822077863782 0.9455928286038779 0.9600778187120567 1.2234865728006175 1.0353145793094136 1.0990513067368985 1.1338355647904896 1.0 13.239613120317891 -5.274162649449468 24.443069526955796 1.0578873367141681 1.2471480930270922 0.4531223758791427 0.08374350997073146 458.019079118314 879915.5649444473 0.02272513272894649 0.04783734471361041 5.319090144812994e-06 5.274162649449468 0.18926075631292405 ADS(ph)PVHMEQQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADSPVHMEQQSR 12 0 O95402 O95402 MED26 Mediator of RNA polymerase II transcription subunit 26 1 ADS(1)PVHMEQQSR 76.868 0.016015 4600500.0 12031.0 17204.0 15946.0 14141.0 16243.0 9208.7 16280.0 10680.0 9731.2 8987.9 True False 14067.61067691856 18911.89942272497 16326.21311554177 13348.72561574056 13060.300751351122 8725.779561010142 14737.84054300691 10399.661316395375 9873.500390378313 10617.335121822753 1.3249662476984596 1.7812284538192322 1.5376940567680728 1.257257632219194 1.2300921654537518 0.8218427186192203 1.388092244796429 0.9794982636481001 0.9299414850421769 1.0 13.374134084582717 -6.0173757013188265 1.7604467537207362 1.051224775904611 1.579949485107967 0.6029608744198036 0.17881350674246888 0.23626001421433324 1.471235446676415 0.05830669907647207 0.09466869445458288 9.607807624586409e-07 6.0173757013188265 0.528724709203356 ADS(ph)PVNGLPK ddPTM_PC-9_AZD4547_30min_R2 2 ADSPVNGLPK 10 0 Q96S94;Q96S94-3;A0A0A0MSF3 Q96S94 CCNL2 Cyclin-L2 1 ADS(1)PVNGLPK;ADS(1)PVNGLPK 96.334 0.005571 68519000.0 217031.0 171726.0 203746.0 291288.0 247193.0 231482.0 223870.0 252337.0 216689.0 229535.0 True False 286042.34347476426 227233.07121503973 201044.19491472878 224136.0519547382 212874.51881176993 217007.39394663658 243793.9963063437 213344.1147774053 228142.73816063858 221499.04951501644 1.2913930967246527 1.0258873422372612 0.9076526303608318 1.01190525397511 0.9610628997183944 0.9797215582720803 1.100654819242535 0.9631829808955534 1.0299942083732134 1.0 17.75694098241388 -4.76869067807361 4.572980506963719 0.9939835750985511 1.3134063218095962 0.7748917653705172 0.04772820453128845 0.08599229169332052 4.073642207258931 0.011875648708239383 0.08935326945835476 1.7033712857104063e-05 4.76869067807361 0.3194227467110451 ADS(ph)PVNGLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADSPVNGLPK 10 0 Q96S94;Q96S94-3;A0A0A0MSF3 Q96S94 CCNL2 Cyclin-L2 1 ADS(1)PVNGLPK 88.021 0.010255 3340900.0 34961.0 34410.0 35705.0 41674.0 47689.0 42517.0 42698.0 51049.0 41479.0 41496.0 True False 40879.20678877478 37825.99739223241 36556.34261196655 39339.140888930946 38344.6827883509 40287.333673099165 38653.33633324997 49709.01784088648 42085.55190444156 49018.89631784473 0.8339479233418238 0.7716615475583917 0.745760214080109 0.8025301229519933 0.7822428832285232 0.8218735365209162 0.7885395069406876 1.0140786834237743 0.8585577209154918 1.0 15.581050381202235 -7.7479999040223895 24.999935933433214 0.9522386424724743 0.7909128748838585 0.7378951731873666 0.04507458400807585 105.3599285682009 195989.9147340903 0.020100019852816328 0.011521209761050383 1.7864879696598016e-08 7.7479999040223895 -0.16132576758861572 ADS(ph)PVNGLPK ddPTM_PC-9_Lapatinib_30min_R1 4 ADSPVNGLPK 10 0 Q96S94;Q96S94-3;A0A0A0MSF3 Q96S94 CCNL2 Cyclin-L2 1 ADS(1)PVNGLPK;ADS(1)PVNGLPK;ADS(1)PVNGLPK;ADS(1)PVNGLPK 122.34 0.00054661 112816000.0 929890.0 830370.0 822820.0 814850.0 878100.0 807190.0 787250.0 748330.0 864660.0 678957.0 True False 916629.5980790578 828447.3292827791 755170.915777052 874776.7872599167 826451.8844110226 772668.3653517937 828009.952956167 783100.1437129753 767272.8855265453 796313.8127966635 1.1510909183652658 1.040352830717908 0.9483333123720193 1.0985327306928034 1.037846978326941 0.9703063703468527 1.0398035795061578 0.9834064550038614 0.9635308005419043 1.0 19.602977557148257 -4.801049240047774 3.7344703864787014 1.0083331954087433 1.1630519019937162 0.516305236811968 0.042247481559568874 0.20127503855777693 4.89707655128253 0.01073555580930688 0.08317949262294465 1.5810687684794678e-05 4.801049240047774 0.1547187065849729 ADS(ph)RESLKPAAKPLPSK ddPTM_PC-9_Lapatinib_30min_R1 1 ADSRESLKPAAKPLPSK 17 3 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ADS(0.78)RES(0.22)LKPAAKPLPSK 81.807 0.017106 0.0 22474.0 15698.0 17456.0 10944.0 17467.0 14625.0 10388.0 11311.0 12954.0 13208.0 True False 22153.516638773166 15661.652245482244 16020.835062108601 11748.858268113769 16439.625401443263 13999.522842540142 10925.839811125637 11836.550352835618 11494.984108332595 15490.985201446265 1.4300908787069835 1.011017184628131 1.0342037548788614 0.758431959964488 1.0612382096852324 0.9037206259310817 0.7053030952547539 0.7640928061651326 0.742043450358432 1.0 13.919141279651251 -1.5228787470390683 0.6562111533210887 0.8272164222182794 54.502111681285 0.6803451813087669 0.1174972771630489 131.38404185112185 0.8283682584291275 0.04939543613494827 10258.704581195789 0.029999999878511183 1.5228787470390683 53.67489525906672 ADSEGSNS(ph)GGTWPK ddPTM_PC-9_AZD4547_30min_R2 1 ADSEGSNSGGTWPK 14 0 Q8TDM6-4;Q8TDM6;Q8TDM6-3 Q8TDM6-4 DLG5 Disks large homolog 5 1 ADS(0.001)EGS(0.251)NS(0.555)GGT(0.194)WPK 65.528 0.038725 8723800.0 14563.0 18682.0 15898.0 22085.0 20810.0 20528.0 21191.0 24434.0 17153.0 19077.0 True False 19193.731070782465 24720.59115357825 15687.182132431324 16993.644459848634 17920.890706747123 19244.38091487263 23076.957947593444 20658.286737462695 18059.67256145646 18409.120036586894 1.0426207788659214 1.3428448021658683 0.8521418786587355 0.9231100903288644 0.9734789425638245 1.0453721240681635 1.2535611643429743 1.1221767632785127 0.9810176980520563 1.0 14.16813304647662 -7.0211290652280605 24.691828930426205 1.1065269200568015 1.0269768493033948 0.03742745575118178 0.1389961973847446 2171.597952273441 2537763.5033664657 0.05561832862061692 0.04355037024243544 9.525130506331388e-08 7.0211290652280605 -0.0795500707534067 ADSEGSNSGGT(ph)WPK ddPTM_PC-9_AZD4547_30min_R2 1 ADSEGSNSGGTWPK 14 0 Q8TDM6-4;Q8TDM6;Q8TDM6-3 Q8TDM6-4 DLG5 Disks large homolog 5 1 ADSEGS(0.006)NS(0.002)GGT(0.992)WPK 108.71 0.0019925999999999998 0.0 16875.0 21590.0 20329.0 20239.0 17298.0 25398.0 19147.0 21208.0 19334.0 21606.0 True False 22240.898978195048 28568.545284538828 20059.424177267352 15573.211239432949 14896.4712852144 23809.85904500854 20851.045907346102 17930.790911357497 20355.95576885672 20849.58051635459 1.066731244820446 1.3702215860951936 0.9621020509996625 0.7469316338147518 0.7144734290231634 1.1419826421127217 1.0000702839556108 0.8600072743570276 0.9763244758276711 1.0 14.347730737173203 -5.3929145784602 6.3807942220683085 0.9137402285286325 1.2156592791906466 0.42439920244887763 0.13703489620261255 0.21149620924632062 9.961219736387184 0.037286344060433234 0.07854658337342882 4.046554757033596e-06 5.3929145784602 0.3019190506620142 ADSEGSNSGGT(ph)WPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ADSEGSNSGGTWPK 14 0 Q8TDM6-4;Q8TDM6;Q8TDM6-3 Q8TDM6-4 DLG5 Disks large homolog 5 1 ADSEGS(0.002)NS(0.001)GGT(0.997)WPK;ADSEGS(0.005)NS(0.004)GGT(0.99)WPK;ADSEGS(0.005)NS(0.031)GGT(0.964)WPK 128.74 6.0491e-05 18134800.0 50971.0 79662.0 68215.0 65579.0 68294.0 45356.0 62483.0 44122.0 43778.0 42094.0 True False 59599.383576861066 87570.3168921829 69841.5043068283 61904.821239986675 54912.28095258101 42977.45151532528 56564.15790225432 42963.844251123286 44418.170430160884 49725.308984079325 1.1985724130129216 1.761081402635839 1.4045464117516016 1.2449358788259495 1.1043125135765854 0.8642973245090438 1.1375325575224602 0.8640236758484322 0.8932708783042929 1.0 15.601692715282455 -6.10059426525266 1.5917906164869544 0.9550600658893361 1.4955755048208201 0.67834335158882 0.15043560722486976 0.20679213973017033 1.04806041535849 0.05075957926984236 0.07891046973310988 7.932420619134887e-07 6.10059426525266 0.540515438931484 ADSEGSNSGGT(ph)WPK ddPTM_PC-9_Lapatinib_30min_R1 2 ADSEGSNSGGTWPK 14 0 Q8TDM6-4;Q8TDM6;Q8TDM6-3 Q8TDM6-4 DLG5 Disks large homolog 5 1 ADSEGS(0.001)NS(0.001)GGT(0.998)WPK;ADSEGS(0.001)NS(0.003)GGT(0.996)WPK 118.2 0.00029107 20283500.0 33401.0 58783.0 47977.0 44858.0 59908.0 55506.0 61571.0 59326.0 52511.0 40980.0 True False 32924.695615006756 58646.89157511675 44032.51625657566 48157.0069619013 56384.3292236597 53132.13777080569 64758.84511078325 62082.502540210946 46596.65821465594 48063.33839758238 0.6850272309978137 1.2202001261332844 0.9161352025183196 1.0019488568094062 1.173125527761839 1.1054608261143648 1.3473646914638926 1.2916810319470804 0.9694844296749845 1.0 15.552649238636603 -6.210275251099858 3.815794767241679 1.171455098018246 0.9670137970485005 0.24318756311591117 0.16322350581331843 0.33113955444806764 10.027136433864001 0.048894515938603236 0.06281782762297915 6.162043344963451e-07 6.210275251099858 -0.20444130096974555 ADSEPES(ph)PLNASYVYK ddPTM_PC-9_AZD4547_30min_R2 2 ADSEPESPLNASYVYK 16 0 Q5T1V6-2;Q5T1V6 Q5T1V6-2 DDX59 Probable ATP-dependent RNA helicase DDX59 1 ADS(0.008)EPES(0.991)PLNASYVYK;ADSEPES(1)PLNASYVYK 242.09 4.5134e-38 25283000.0 51717.2 53889.0 59161.0 65591.0 70680.0 71550.0 59946.0 84385.0 59216.0 57868.0 True False 68162.19381541392 71307.56539316868 58376.48648488927 50470.00832084823 60867.302025607205 67075.96718916296 65281.077869210276 71345.2372243919 62346.03686813999 55842.05893364837 1.220624653120408 1.2769508638264297 1.0453856394201424 0.9037992023327217 1.0899902902564864 1.2011728877845056 1.1690306395539134 1.2776254777633544 1.1164709550236975 1.0 15.769064515198068 -6.7522139032888315 24.948178188022265 1.1712222511676302 1.1020215269998712 0.024778379298127873 0.11482582412634858 595.08965995538 1609278.3566003682 0.04125887525844711 0.040696407729834995 1.7692373402911413e-07 6.7522139032888315 -0.06920072416775902 ADSEPES(ph)PLNASYVYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADSEPESPLNASYVYK 16 0 Q5T1V6-2;Q5T1V6 Q5T1V6-2 DDX59 Probable ATP-dependent RNA helicase DDX59 1 ADS(0.031)EPES(0.969)PLNASYVYK 112.12 0.00038233 9423400.0 4371.7 4357.0 6719.6 7472.5 7783.1 6667.9 8130.4 5373.4 5095.0 3578.2 True False 5111.742464989183 4789.534165590136 6879.820748224907 7053.840051171873 6258.057426450841 6318.223585832913 7360.229653001441 5232.353943587911 5169.504736206989 4226.899334984386 1.209336220212603 1.1331081689003195 1.6276282454335576 1.6687977385195831 1.480531455919794 1.4947655681173804 1.7412834017795764 1.2378704882517009 1.22300162045995 1.0 12.045384039176962 -8.243480137003639 2.04252144749992 1.0424656572195579 1.4769937640125632 0.3857061238444638 0.18840340621676177 0.3560962978279329 2.7062787722059087 0.18868206322482434 0.05542203964979486 5.708471839782502e-09 8.243480137003639 0.43452810679300535 ADSEPES(ph)PLNASYVYK ddPTM_PC-9_Lapatinib_30min_R1 1 ADSEPESPLNASYVYK 16 0 Q5T1V6-2;Q5T1V6 Q5T1V6-2 DDX59 Probable ATP-dependent RNA helicase DDX59 1 ADSEPES(1)PLNASYVYK 191.41 1.4490000000000001e-08 14063000.0 15383.0 19622.0 20644.0 19782.0 20557.0 25745.0 25914.0 19991.0 27415.0 20193.0 True False 15163.635599103294 19576.566464572086 18946.73000814448 21236.8342708175 19347.877676617023 24643.94636452622 27255.70012182417 20919.854840733507 24327.23400725169 23683.333144518823 0.6402661106261011 0.8265967608998824 0.8000026808950005 0.8966995541221979 0.8169406543645577 1.0405607274172772 1.1508388602020794 0.883315482372257 1.0271879324925972 1.0 14.531584516794515 -5.46018148285437 0.5598026771412941 1.0228329233678521 0.6013611742583548 0.651054608906041 0.08316568323737145 1.38955715389449 0.5590889826973562 0.05442576659664212 0.34832011626697384 3.4659198642622454e-06 5.46018148285437 -0.42147174910949736 ADSGPTQPPLS(ph)LSPAPETK ddPTM_PC-9_AZD4547_30min_R2 1 ADSGPTQPPLSLSPAPETK 19 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0;X6RGP5;A0A0C4DH09 O15027 SEC16A Protein transport protein Sec16A 1 ADSGPTQPPLS(0.62)LS(0.378)PAPET(0.001)K 80.96 0.0023129 31618000.0 33005.0 30492.0 47090.0 51514.0 37444.0 40275.0 31637.0 54600.0 40583.0 40167.0 True False 43499.90345335272 40347.94269644083 46465.555831940575 39638.24318336621 32245.546930487235 37756.59788320809 34452.63171101 46162.82458318179 42728.134528163435 38760.76555588327 1.1222663646990358 1.0409480338635015 1.1987780727640411 1.0226382945460104 0.8319120241316511 0.9740931929936362 0.8888532312742372 1.190967823290967 1.1023552789884972 1.0 15.242309444955932 -5.976740591035855 21.47121613896941 0.9942277227652828 1.1123623048057785 0.22922460395193844 0.10047531884816656 77.78072611522907 71797.35955022767 0.030583443440169264 0.04535427519823606 1.055016881638083e-06 5.976740591035855 0.11813458204049565 ADSGPTQPPLS(ph)LSPAPETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ADSGPTQPPLSLSPAPETK 19 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0;X6RGP5;A0A0C4DH09 O15027 SEC16A Protein transport protein Sec16A 1 ADSGPTQPPLS(0.668)LS(0.323)PAPET(0.009)K;ADSGPTQPPLS(0.81)LS(0.19)PAPETK;ADSGPTQPPLS(0.71)LS(0.285)PAPET(0.005)K;ADSGPTQPPLS(0.964)LS(0.036)PAPETK 224.12 4.4046e-35 176284000.0 254152.0 239433.2 256254.0 294673.0 371073.0 329398.0 347752.0 358503.0 285922.0 272186.0 True False 297174.91386918887 263202.5457371067 262364.067208707 278163.4271527555 298363.90941981896 312123.7890079622 314810.4130535459 349092.67611532717 290103.06833872 321531.1671768101 0.9242491683730687 0.8185910810704442 0.8159833135692034 0.8651211936782269 0.9279470853155226 0.9707419400381961 0.979097658922849 1.0857195561491586 0.9022548914494259 1.0 18.294599064407002 -6.527645750990492 1.7368399087638076 0.9965666660503197 0.8479910726275715 0.6054373872969621 0.050108488894887115 0.22820022183900518 1.395076595599034 0.01889924704034961 0.020567477660669884 2.967250754949246e-07 6.527645750990492 -0.1485755934227483 ADSGPTQPPLSLS(ph)PAPETK ddPTM_PC-9_AZD4547_30min_R2 4 ADSGPTQPPLSLSPAPETK 19 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0;X6RGP5;A0A0C4DH09 O15027 SEC16A Protein transport protein Sec16A 1 ADSGPTQPPLS(0.08)LS(0.918)PAPET(0.002)K;ADSGPTQPPLS(0.069)LS(0.931)PAPETK;ADSGPTQPPLSLS(0.997)PAPET(0.003)K;ADSGPTQPPLS(0.061)LS(0.939)PAPETK 175.02 1.3125e-08 312790000.0 732145.0 627812.0 775880.0 945960.0 826650.0 756710.0 744782.0 942450.0 819120.0 790290.0 True False 964951.8804379625 830739.9514672011 765591.324249013 727883.5369363105 711883.916517661 709392.8040770302 811066.1551660862 796816.0078465155 862417.0109333768 762622.1876455556 1.2653079022222782 1.0893204589705756 1.0038933257536395 0.9544484132877201 0.933468666464401 0.9302021572007227 1.0635228928627054 1.0448371693807212 1.1308574873698836 1.0 19.54060897972135 -4.800181606004527 2.2309251774883245 1.0040862313428633 1.3262050187376306 0.6410139701322379 0.05859168937713422 0.4153048503414073 2.517166886866338 0.01727228278638835 0.26517212744483476 1.5842305868754893e-05 4.800181606004527 0.3221187873947673 ADSGPTQPPLSLS(ph)PAPETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ADSGPTQPPLSLSPAPETK 19 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0;X6RGP5;A0A0C4DH09 O15027 SEC16A Protein transport protein Sec16A 1 ADSGPTQPPLS(0.034)LS(0.961)PAPET(0.005)K;ADSGPTQPPLS(0.221)LS(0.778)PAPET(0.001)K 161.55 1.3401e-20 37854000.0 49258.0 52808.0 53360.1 67695.0 73235.0 67157.0 75062.0 68343.0 60759.0 56901.0 True False 57596.406510153276 58050.429244086314 54632.40715330617 63902.26862015113 58885.12747184633 63635.168696858214 67951.58395818077 66549.06866539415 61647.48543026511 67216.70087193194 0.856876427480304 0.8636310394746963 0.81278025319031 0.9506903461671556 0.8760490578679283 0.9467166324943912 1.0109330430788175 0.9900674654084879 0.917145361652339 1.0 16.03653211361894 -6.444991499275919 0.9851482315483002 0.9799108424363904 0.8493447441586383 0.6354027536106559 0.03902461780878881 0.3485988000085259 0.7277418265884324 0.019580028019879413 0.024996332921205185 3.5892896012269567e-07 6.444991499275919 -0.13056609827775212 ADSGPTQPPLSLS(ph)PAPETK ddPTM_PC-9_Lapatinib_30min_R1 4 ADSGPTQPPLSLSPAPETK 19 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0;X6RGP5;A0A0C4DH09 O15027 SEC16A Protein transport protein Sec16A 1 ADSGPTQPPLS(0.031)LS(0.949)PAPET(0.02)K;ADS(0.001)GPT(0.018)QPPLS(0.176)LS(0.804)PAPET(0.001)K;ADSGPTQPPLS(0.006)LS(0.994)PAPETK;ADSGPTQPPLS(0.14)LS(0.86)PAPETK 180.41 4.490399999999999e-09 294659000.0 326485.0 405637.0 448105.0 423655.0 484862.0 522229.0 529013.0 515592.0 502708.0 432016.0 True False 321829.2640299841 404697.7724487638 411263.5366353227 454812.00197164976 456343.37043536914 499894.4830452579 556402.7046595116 539548.2865811345 446087.73129007814 506689.3899748644 0.6351608508043739 0.7987097824741107 0.8116679464232011 0.8976150102417023 0.9006373124529157 0.9865896009191282 1.098113983967798 1.0648501769652217 0.8803968271611282 1.0 18.950742093723733 -5.126871919215747 0.5750960559985666 1.0199369517454637 0.5138976926767429 0.7776440156064205 0.06183753578542856 1.3012600434517902 0.4313575265766091 0.036898494398450395 0.4163430207649362 7.46668931232028e-06 5.126871919215747 -0.5060392590687208 ADSLDCSR ddPTM_PC-9_Lapatinib_30min_R1 1 ADSLDCSR 8 0 Q14692 Q14692 BMS1 Ribosome biogenesis protein BMS1 homolog 0 94.662 0.028362000000000002 0.0 56314.0 60572.0 77080.0 54450.0 56803.0 63638.0 55104.0 51430.0 73218.0 47962.0 False True 55510.95203327717 60431.74925553259 70742.77993740448 58454.43463987529 53461.95921899484 60916.35108742356 57957.01549405725 53819.62555444573 64971.41782027918 56252.167794652145 0.9868233387185935 1.0743008069686835 1.2576009549649738 1.0391499018004513 0.9503982035706974 1.0829156186442086 1.0303072355474125 0.9567564711623847 1.1550029157535147 1.0 15.779621074213912 -5.96975643422242 24.998143985930973 1.0266211848741433 1.1106022476277104 0.14744339614475188 0.08325374496006961 359.2651032466165 296952.2678065719 0.023379052903997947 0.03467629377332952 1.0721204149492993e-06 5.96975643422242 0.08398106275356709 ADT(ph)PGPEDGGVK ddPTM_PC-9_AZD4547_30min_R2 1 ADTPGPEDGGVK 12 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 ADT(1)PGPEDGGVK 80.469 0.032981 0.0 17231.0 16163.0 17151.0 19784.0 19549.0 19280.0 18772.0 18046.0 19050.0 18525.0 True False 22710.09957293504 21387.37366530806 16923.566533735684 15223.104459753016 16834.95879030271 18074.4185521602 20442.67163381737 15257.40535582598 20056.9441086542 17876.445388571166 1.2703923559352657 1.1963996868740758 0.9466964022140173 0.8515733485520285 0.9417397264595844 1.0110745262430978 1.1435534967643428 0.8534921246469055 1.1219760792868294 1.0 14.125772274342324 -5.165364950612453 4.2110226963141555 0.9790897211949883 1.2521668148550729 0.544994678327464 0.09191440642220218 0.16551128642345153 5.084418479204874 0.02398994606664485 0.07115510701730811 6.833371773222841e-06 5.165364950612453 0.2730770936600846 ADT(ph)PGPEDGGVK ddPTM_PC-9_Lapatinib_30min_R1 2 ADTPGPEDGGVK 12 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 ADT(1)PGPEDGGVK;ADT(1)PGPEDGGVK 106.54 0.0040555999999999995 7102700.0 43666.0 59749.0 55629.0 54305.0 60885.0 71300.0 74259.0 71895.0 59111.0 61299.0 True False 43043.3148326363 59610.654861467614 51055.398354149875 58298.77085616946 57303.86400451559 68250.6652084179 78103.7676679225 75235.50416560125 52453.29671357482 71894.45047421665 0.598701492934741 0.8291412545512905 0.7101438013280282 0.8108938933621451 0.7970554559710608 0.9493175726114561 1.0863671278207028 1.0464716493324169 0.7295875602023836 1.0 16.13359279301902 -6.664553256567913 2.422288025532761 0.9763454716275207 0.7432289925820524 0.5074811975646091 0.1060802922042212 0.24659666855129575 2.952656512613973 0.03926842085271873 0.038539586552149695 2.1649443807076188e-07 6.664553256567913 -0.23311647904546828 ADT(ph)SQEICSPR ddPTM_PC-9_Lapatinib_30min_R1 1 ADTSQEICSPR 11 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 ADT(0.914)S(0.086)QEICSPR 109.16 0.0051237999999999995 7460200.0 19186.0 18057.0 26485.0 20259.0 25204.0 23388.0 24242.0 21682.0 26975.0 17756.0 True False 18912.404121718508 18015.19012591877 24307.50553505651 21748.914442042846 23721.550272970526 22387.749760090872 25497.132142983024 22689.424874032517 23936.791440657085 20825.1009416172 0.9081542593593711 0.8650709629895209 1.167221498863423 1.0443605773155935 1.1390845278240653 1.0750367944364128 1.2243461491237801 1.0895229241693434 1.1494201880587978 1.0 14.346035868063087 -5.256861432385961 24.982059321479678 1.1156903213345248 0.886612586791997 0.6799398977994331 0.061550193389644285 190.0538099707307 1037122.8588269344 0.014732445644674439 0.0363534003630541 5.5352669133038145e-06 5.256861432385961 -0.2290777345425279 ADTLTLEER ddPTM_PC-9_Lapatinib_30min_R1 1 ADTLTLEER 9 0 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;Q9UHD8-8;Q9UHD8-3;Q9UHD8-9;K7EL40;Q9UHD8-4 Q9UHD8 SEPT9 Septin-9 0 115.49 0.00096898 0.0 21870.0 19196.0 23808.0 20072.0 25768.0 21650.0 23734.0 24081.0 25104.0 22669.0 False True 21558.1297895332 19151.552841398723 21850.598141537674 21548.16183822913 24252.376901837186 20724.07996861498 24962.830388646104 25199.89117201259 22276.523163160546 26587.306445456186 0.8108429424304288 0.7203269304729345 0.8218432426151983 0.8104680285095878 0.912178785451279 0.7794727160921846 0.9389003146993212 0.9478166291011887 0.8378631061728947 1.0 14.698450005010548 -2.3373164740594308 0.09782953739178463 1.090020496384773 0.2229689417149814 0.564121521791472 0.054852170661230014 77.88475654930326 0.6469010597312236 0.8015142566055913 9.021446098875833 0.004599213028984254 2.3373164740594308 -0.8670515546697917 ADTQTYQPYNK ddPTM_PC-9_Lapatinib_30min_R1 2 ADTQTYQPYNK 11 0 P84090 P84090 ERH Enhancer of rudimentary homolog 0 ; 183.03 0.006559899999999999 9736600.0 43690.0 42239.0 50371.0 44947.0 46441.0 39645.0 44863.0 42507.0 42616.0 49270.0 False True 43066.97258823526 42141.19819065644 46229.69081768288 48252.55231879657 43709.43168651899 37949.47576700881 47185.78662365512 44482.03039943273 37816.137313625295 57786.25385185173 0.7452805765649264 0.7292599083978524 0.8000119013806165 0.8350178304083011 0.7563984299549528 0.6567215079264519 0.8165572861778974 0.7697683693681301 0.6544140655072677 1.0 15.81843872593754 -10.837676003856702 3.8103367043889285 1.0005994779112495 0.7545301429368375 0.6275062753954529 0.05739670380574959 85098637.47565655 150713731.0909439 589841.1507756615 0.014625696172776984 1.4531953387084375e-11 10.837676003856702 -0.24606933497441197 ADTS(ph)QEICSPR ddPTM_PC-9_AZD4547_30min_R2 3 ADTSQEICSPR 11 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 ADT(0.052)S(0.948)QEICSPR;ADT(0.111)S(0.889)QEICSPR;ADT(0.05)S(0.949)QEICSPR 127.78 0.0003432 46937000.0 85479.0 89741.0 110181.0 135143.0 104970.0 98920.0 89534.0 113710.0 91155.0 90873.0 True False 112659.5439263484 118748.02326909665 108719.92794901357 103987.86928853637 90396.7274140918 92734.5167624318 97502.35254965906 96138.73229585339 95973.26720337923 87691.56392958855 1.2847249938067902 1.354155610275633 1.2397991674126103 1.1858366372851197 1.0308486171677282 1.0575078446188104 1.111878362985384 1.0963281755705423 1.0944412769333254 1.0 16.42015043929645 -5.846652638218197 1.9385236413401605 1.0722701520742348 1.315332324800762 0.8715261200109687 0.039533856682656354 0.10811946840695873 0.8292697138292856 0.012254989798053532 0.02253667653944234 1.4234668635160794e-06 5.846652638218197 0.2430621727265272 ADTS(ph)QEICSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ADTSQEICSPR 11 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 ADT(0.235)S(0.765)QEICSPR;ADT(0.303)S(0.561)QEICS(0.136)PR;ADT(0.126)S(0.874)QEICS(0.001)PR;ADT(0.064)S(0.936)QEICSPR 108.23 0.0022107 38607300.0 122626.0 136322.0 134679.0 159646.0 172356.0 145117.0 143866.0 135393.0 132606.0 116713.0 True False 143384.15982610063 149855.14723928788 137890.25813295163 150701.5521993151 138584.0790678987 137506.8090561219 130237.97098035812 131839.0772107416 134545.11188409475 137872.14300040054 1.039979191631801 1.0869138897685267 1.0001313908100422 1.0930529468804826 1.0051637412170789 0.9973501975357156 0.9446286113067798 0.9562415897920626 0.975868721237646 1.0 17.0729714649 -6.6563384382747195 2.1614606970923926 0.9671871873464949 1.0532850594833267 0.6242258848095956 0.029026489367898218 0.1866830187569389 1.7845357112596372 0.010396049305101145 0.0102597358456734 2.2062847428958511e-07 6.6563384382747195 0.08609787213683184 ADTS(ph)QEICSPR ddPTM_PC-9_Lapatinib_30min_R1 2 ADTSQEICSPR 11 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 ADT(0.032)S(0.968)QEICSPR;ADT(0.232)S(0.764)QEICS(0.004)PR 121.45 0.00076674 33016000.0 67441.0 81977.0 77570.0 67229.0 84009.0 67909.0 73370.0 80262.0 78783.0 55894.0 True False 66479.27897283513 81787.18729315196 71192.49402885915 72173.24492936967 79067.75578804874 65004.69037361079 77168.73959783277 83991.2655308366 69909.62891823114 65555.20342592645 1.0140961433817048 1.2476078635857901 1.0859930304282026 1.1009537177460096 1.206124787293059 0.9916022981617668 1.1771565881117116 1.2812295766230337 1.066423796506481 1.0 16.000422678056594 -8.521164211159414 24.974236417324875 0.999999986531163 1.1397307404341348 0.19910754378761197 0.08921084251749672 217.9291818767681 3174385.0346190566 0.08307814969499339 0.021450686013255598 3.0118669913263468e-09 8.521164211159414 0.13973075390297185 ADTSQEICS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ADTSQEICSPR 11 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 ADTSQEICS(1)PR 73.36 0.024934 15601000.0 26830.0 25977.0 34439.0 31950.0 32883.0 25616.0 28301.0 29469.0 21728.0 20454.0 True False 31371.78908334509 28555.824883987832 35260.15637063482 30159.945083297578 26439.81220259059 24272.651865609234 25620.124398503616 28695.469974986467 22045.730894662523 24162.148286225103 1.2983857524469469 1.1818413059019084 1.4593137974712584 1.248231106192318 1.0942657866918228 1.0045734169857374 1.0603413278905216 1.187620804038597 0.9124077310307231 1.0 14.560461111699901 -6.254063505169236 3.29934987833054 1.0474796143879295 1.30633032369802 0.6576385613359509 0.09078452381932695 0.1584073079129214 3.6196105902125866 0.028301255188127542 0.03533390667152738 5.571042798139975e-07 6.254063505169236 0.25885070931009047 ADTSQEICS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 ADTSQEICSPR 11 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 ADT(0.009)S(0.006)QEICS(0.985)PR 69.352 0.034931 14222000.0 14759.0 20590.0 23750.0 21489.0 21585.0 20961.0 21478.0 22724.0 21771.0 15696.0 True False 14548.53395353088 20542.325120045818 21797.36667765122 23069.372745202574 20315.41273774277 20064.54689247753 22590.025747338885 23779.83999804053 19318.920721206494 18409.032686394658 0.7902932327499799 1.1158829184559917 1.184058231031375 1.2531550754566358 1.1035567747542236 1.0899294511713478 1.2271163907506244 1.291748480386762 1.0494261730266956 1.0 14.168126200957232 -4.761136003211257 3.7613654964293364 1.1625158718012079 0.7430371558420047 0.5944953697117652 0.08804899657716901 0.1823095985595584 4.467658691649193 0.021663776176246402 0.22023206344236598 1.7332611264924385e-05 4.761136003211257 -0.41947871595920316 ADVDVSGPK ddPTM_PC-9_Lapatinib_30min_R1 1 ADVDVSGPK 9 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 93.649 0.028075 4737900.0 57731.0 60871.0 49741.0 42196.0 52657.0 50620.0 59147.0 55654.0 45722.0 45269.0 False True 56907.74535343123 60730.056939403126 45651.48698581256 45299.23460172958 49559.81878764517 48455.10060098337 62209.342251506365 58239.888014915894 40572.306885995305 53093.68633284911 1.071836394946688 1.1438282239187711 0.8598289201397558 0.8531943764037138 0.9334409081514927 0.9126339485492488 1.171690017180393 1.096926810653244 0.7641644362691988 1.0 15.696252691843474 -5.2470528238192005 24.743674037788736 0.9551258665528204 1.1078323272563548 0.2358510857372279 0.1139413254878991 1127.040709719109 1938406.8929820005 0.03075508805328452 0.0805412188511093 5.661704207838875e-06 5.2470528238192005 0.15270646070353444 ADVGRLS(ph)PEVK ddPTM_PC-9_AZD4547_30min_R2 1 ADVGRLSPEVK 11 1 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4;A0A2R8Y670 P49815 TSC2 Tuberin 1 ADVGRLS(1)PEVK 61.657 0.027551999999999997 13982000.0 142920.0 170540.0 147690.0 144510.0 134670.0 177220.0 173530.0 155100.0 197030.0 174020.0 True False 188365.58707932607 225663.7199085343 145731.53410106845 111195.45215724364 115973.3950734089 166138.4053845344 188973.83382784613 131132.85884343425 207444.60355528293 167927.61276756585 1.121707049691995 1.343815446366661 0.8678235324096477 0.6621630018116968 0.6906153976828784 0.9893453652228835 1.1253291267196839 0.7808891979244627 1.2353215777706186 1.0 17.35747995025922 -5.269584489339712 24.80631256046458 0.9036715510160225 1.2327612506965235 0.32699099444591795 0.17902206047224528 548.653250950377 1670953.0114343513 0.04856753117842016 0.10397661193085773 5.375458466869659e-06 5.269584489339712 0.32908969968050106 ADVGRLS(ph)PEVK ddPTM_PC-9_Lapatinib_30min_R1 2 ADVGRLSPEVK 11 1 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4;A0A2R8Y670 P49815 TSC2 Tuberin 1 ADVGRLS(1)PEVK;ADVGRLS(1)PEVK 88.22399999999999 0.0046919 22186100.0 103839.0 188148.0 140258.0 152276.0 174615.0 162961.0 171659.0 168335.0 158068.0 131511.0 True False 102358.23681825961 187712.35486577888 128726.52865153684 163474.88501784482 164344.48900629865 155991.537910645 180546.66308606247 176156.4586371303 140264.71731016817 154242.50112260712 0.6636188863204131 1.216995014341518 0.8345723630947369 1.0598562901148685 1.0654941913556075 1.0113395255867097 1.1705377037587468 1.1420747028544604 0.9093778711398874 1.0 17.234840825359584 -4.744931623119073 24.988843788441343 1.0473317946064524 0.6636177730241727 0.5198333537432238 0.11011898857373335 781.5738977145943 1183054.51775301 0.026395203031397335 0.7122274490771815 1.799154158114537e-05 4.744931623119073 -0.38371402158227974 ADVVESWIGEK ddPTM_PC-9_Lapatinib_30min_R1 1 ADVVESWIGEK 11 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 137.17 0.00040874 1994200.0 15359.0 12281.0 12336.0 11585.0 12896.0 10321.0 10442.0 10669.0 11638.0 9542.8 False True 15139.977843504355 12252.564099042396 11321.781698337069 12436.999546427094 12137.482634511507 9879.59488942611 10982.635666901604 11164.720689099384 10327.205886426955 11192.260265018282 1.3527185291450712 1.0947354519031445 1.0115724107777953 1.1112142902269062 1.0844532156250462 0.8827166859499377 0.9812705750980555 0.9975394089069771 0.9227095905466853 1.0 13.450213796010841 -1.5228787452803818 0.6624755751498401 0.9790787228622368 35.16698696447038 0.7578813410173848 0.061030780372992345 121.09665866982415 0.7451457220162289 0.026647250552134703 6088.372779375376 0.029999999999996942 1.5228787452803818 34.18790824160815 ADVVPQQADPEFPRAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 ADVVPQQADPEFPRASPR 18 1 Q5T5Y3-2;Q5T5Y3;Q5T5Y3-3 Q5T5Y3-2 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1 1 ADVVPQQADPEFPRAS(1)PR;ADVVPQQADPEFPRAS(1)PR 90.706 0.00061911 24478000.0 85845.0 85377.0 159767.0 212674.0 206437.0 142161.0 133688.0 177756.0 145834.0 175349.0 True False 113141.92431307597 112973.44561176795 157648.3851900968 163645.29508054577 177776.7859120018 133271.65019676555 145585.97301202724 150287.89462652142 153542.48751398816 169210.08488208152 0.6686476423194391 0.6676519646597687 0.9316725140818777 0.967113131552332 1.0506276031708761 0.7876105628670974 0.8603859108839916 0.8881733894953925 0.9074074256329833 1.0 17.36845602974921 -5.259729805133336 24.609024032827257 0.9190315123937143 0.6681497686924633 0.6848669333778069 0.06938564528727469 69.67702301395519 1002960.2328921962 0.019058249088123175 0.04531262192397797 5.498828752600098e-06 5.259729805133336 -0.25088174370125094 ADVVPQQADPEFPRAS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ADVVPQQADPEFPRASPR 18 1 Q5T5Y3-2;Q5T5Y3;Q5T5Y3-3 Q5T5Y3-2 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1 1 ADVVPQQADPEFPRAS(1)PR;ADVVPQQADPEFPRAS(1)PR 71.263 0.004339 14556700.0 73226.0 78073.0 99606.0 105998.0 124403.0 136470.0 114779.0 122289.0 111318.0 107930.0 True False 85621.71552057513 85823.57147351807 101980.98479785844 100059.27571015281 100027.12518440776 129313.2729582953 103906.30219200198 119079.04332590567 112945.81515703414 127496.85462658988 0.6715594339275445 0.6731426569296658 0.7998705936435704 0.7847979936697601 0.7845458264626615 1.0142467697499309 0.8149714947582086 0.9339763218054429 0.8858713847320193 1.0 16.960102130379028 -3.2546198772913213 0.23345499589587662 0.9860949401106726 1.9391363489509113e-18 0.7184923702815398 0.0608040877001605 11.95980859004905 0.3154542746450023 0.0892510777622748 3.836696839773022 0.0005563910337429312 3.2546198772913213 -0.9860949401106726 ADVVPQQADPEFPRAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 ADVVPQQADPEFPRASPR 18 1 Q5T5Y3-2;Q5T5Y3;Q5T5Y3-3 Q5T5Y3-2 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1 1 ADVVPQQADPEFPRAS(1)PR;ADVVPQQADPEFPRAS(1)PR 94.72 0.00044377 24655000.0 201214.0 161701.0 178403.0 151523.0 166366.0 159999.0 132328.0 140232.0 170361.0 129894.0 True False 198344.65146187186 161326.59126937969 163735.393995495 162666.50688591058 156580.6789681406 153156.21574588586 139179.29635412316 146747.69066208482 151173.15019913923 152346.00482712445 1.3019353654002588 1.058948617999179 1.0747600121269654 1.067743831356112 1.0277964239746324 1.0053182288546445 0.9135736543407076 0.9632526355292851 0.9923013758758156 1.0 17.21699214123725 -1.5228787452806105 0.5413720965388295 0.9761525418327277 13.381842455153897 0.8307774213217758 0.04073251069562553 53.448791877303215 0.5029998322100319 0.021732371120266908 768.3698682060984 0.029999999999981146 1.5228787452806105 12.40568991332117 ADY(ph)DTLSLR ddPTM_PC-9_AZD4547_30min_R2 3 ADYDTLSLR 9 0 Q9Y446;Q9Y446-2;E9PKC4;E9PK71;E9PQ15;E9PJR7;E9PRW6 Q9Y446 PKP3 Plakophilin-3 1 ADY(0.998)DT(0.002)LSLR;ADY(0.996)DT(0.004)LSLR;ADY(0.94)DT(0.06)LSLR 167.23 0.00024184 31507700.0 45309.0 48230.0 74452.0 115996.0 106108.0 93391.0 64722.0 92063.0 87729.0 88363.0 True False 59716.31951425416 63819.404310945254 73464.71783392747 89254.91432033519 91376.73575740159 87551.24600647259 70482.13261687227 77836.77874727947 92366.17583769673 85269.43826560388 0.7003250018869026 0.7484440569686364 0.8615597725071654 1.046739794887789 1.0716235220498842 1.026759971535888 0.8265814112358644 0.9128332533964563 1.083227211489155 1.0 16.37974113207582 -5.438331513125062 2.7081292082337893 0.9886567681513112 0.7191090438822787 0.6809890409484033 0.0742389309848975 0.17714253746286546 2.5028877127999367 0.02278208349869586 0.05586429785200541 3.6447562291745046e-06 5.438331513125062 -0.2695477242690325 ADY(ph)DTLSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ADYDTLSLR 9 0 Q9Y446;Q9Y446-2;E9PKC4;E9PK71;E9PQ15;E9PJR7;E9PRW6 Q9Y446 PKP3 Plakophilin-3 1 ADY(0.963)DT(0.037)LSLR;ADY(0.997)DT(0.003)LSLR 195.06 0.00025059999999999997 21396400.0 26867.0 22088.0 42798.0 32387.0 51969.0 37464.0 52723.0 36570.0 42749.0 31587.0 True False 31415.052452561802 24280.75066549343 43818.466632318836 30572.46139007071 41786.04751258798 35499.32188839726 47728.69575853523 35610.07624911787 43374.12325183763 37313.47305744556 0.8419224981871051 0.6507234163947231 1.17433363988548 0.8193410820537451 1.119864866190738 0.9513808010780624 1.2791276675064533 0.9543490147458199 1.1624252501251078 1.0 15.187409028890956 -5.249266672914797 0.8793837070748672 1.0776731410932117 0.6808042954300911 0.3342828331664758 0.14886939948046815 1.3526535705402718 1.301277556687854 0.053439419833802876 0.45170053715243086 5.632916676421992e-06 5.249266672914797 -0.39686884566312053 ADY(ph)DTLSLR ddPTM_PC-9_Lapatinib_30min_R1 3 ADYDTLSLR 9 0 Q9Y446;Q9Y446-2;E9PKC4;E9PK71;E9PQ15;E9PJR7;E9PRW6 Q9Y446 PKP3 Plakophilin-3 1 ADY(0.996)DT(0.004)LSLR;ADY(0.963)DT(0.037)LSLR;ADY(0.855)DT(0.145)LSLR 180.87 8.439700000000001e-05 21988000.0 53516.0 51295.0 67884.0 38734.4 72003.0 51513.0 61018.0 50104.0 82194.0 38854.9 True False 52752.85202636755 51176.229579055376 62302.83955981789 41583.05699017053 67767.92510334466 49309.909072668066 64177.21347663305 52432.01475364476 72936.44617880891 45570.917694100135 1.1575990718571207 1.1230019531882487 1.3671622761260294 0.9124911038505179 1.4870871277652211 1.0820477525527645 1.4082931993476573 1.1505586766016105 1.6005042221972121 1.0 15.47582580298303 -6.27390074723998 24.958391396607357 1.2913186060626292 1.1550662275048664 0.11406084349102985 0.2002349351556696 1767.9365405792555 3540924.3019989603 0.05751098005032701 0.06565945863644455 5.322298800815485e-07 6.27390074723998 -0.13625237855776273 ADYDTLS(ph)LR ddPTM_PC-9_AZD4547_30min_R2 4 ADYDTLSLR 9 0 Q9Y446;Q9Y446-2;E9PKC4;E9PK71;E9PQ15;E9PJR7;E9PRW6 Q9Y446 PKP3 Plakophilin-3 1 ADYDT(0.001)LS(0.999)LR;ADYDTLS(1)LR;ADYDTLS(1)LR;ADYDT(0.001)LS(0.999)LR 125.23 0.0014334 63266000.0 97473.0 83385.0 135085.0 186766.0 157969.0 144218.0 122219.0 141157.0 121157.0 138877.0 True False 128467.38643565091 110337.5705674512 133293.68463702907 143709.98420593565 136037.73109342298 135200.02566158914 133096.2542304246 119344.42911516858 127561.11167308231 134014.95850086914 0.9586048294363928 0.8233227977064637 0.9946179600254446 1.0723428624201203 1.015093632943525 1.0088427976546537 0.9931447632359742 0.8905306575489077 0.9518423398404069 1.0 17.032034515049617 -5.289312862436247 23.70083411957677 0.9914000105609415 0.8909638157731243 0.35961437282913045 0.05328676808108906 373.50438601227 317590.3630626255 0.014972439780029358 0.03118152118800465 5.136734718052378e-06 5.289312862436247 -0.10043619478781718 ADYDTLS(ph)LR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ADYDTLSLR 9 0 Q9Y446;Q9Y446-2;E9PKC4;E9PK71;E9PQ15;E9PJR7;E9PRW6 Q9Y446 PKP3 Plakophilin-3 1 ADYDTLS(1)LR;ADYDTLS(1)LR;ADYDTLS(1)LR;ADYDT(0.002)LS(0.998)LR 118.23 0.0018100999999999998 55038000.0 128143.0 97817.0 132750.0 136750.0 154078.0 115362.0 115932.0 112364.0 106897.0 95102.0 True False 149835.07896038337 107527.62530996795 135915.26345717828 129088.3408494819 123887.52195817756 109312.21363680554 104950.08168500474 109414.5640594991 108460.16639574466 112343.23977298218 1.3337258144162736 0.9571348087099375 1.209821469737114 1.1490530370170686 1.1027590285674822 0.9730199508016539 0.934191339835693 0.973931001817277 0.9654356293704521 1.0 16.777553787744765 -6.6801720827472355 3.0887465252262527 0.9635029988067326 1.1495489830717132 0.5220506971088097 0.0877362768584745 0.20728183246624488 3.9809867186276326 0.029604744942546366 0.028844148032137792 2.088468442239986e-07 6.6801720827472355 0.18604598426498054 ADYDTLS(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 3 ADYDTLSLR 9 0 Q9Y446;Q9Y446-2;E9PKC4;E9PK71;E9PQ15;E9PJR7;E9PRW6 Q9Y446 PKP3 Plakophilin-3 1 ADYDTLS(1)LR;ADYDTLS(1)LR;ADYDTLS(1)LR 107.11 0.0025241 37886300.0 110284.0 79270.0 107040.0 87573.0 89179.0 88826.0 63466.4 61148.0 86231.0 50988.0 True False 108711.3299363916 79086.45518533431 98239.58438634867 94013.41055496395 83933.66655265978 85027.11904351934 66752.37964851972 63989.159311748896 76518.75672731429 59801.20786276064 1.8178784981379654 1.3224892608663006 1.6427692332201929 1.5720988574464547 1.4035446699551848 1.4218294593421976 1.1162379830472908 1.0700312184094893 1.2795520268239262 1.0 15.867887003772436 -6.98227137193168 1.2714522879941939 1.1054623452459829 1.5725685964190452 0.6947301446240636 0.13769436735002136 0.25651245758159164 0.8499127140665063 0.07234862345481123 0.05330347388036492 1.0416663335303599e-07 6.98227137193168 0.46710625117306237 AEADKIYSFTDNAPS(ph)PSIGGSSR ddPTM_PC-9_AZD4547_30min_R2 2 AEADKIYSFTDNAPSPSIGGSSR 23 1 O15014 O15014 ZNF609 Zinc finger protein 609 1 AEADKIYSFTDNAPS(0.882)PS(0.117)IGGSSR;AEADKIYSFTDNAPS(0.962)PS(0.038)IGGSSR 154.71 2.7652e-07 25984000.0 63136.0 55303.0 85802.0 139187.0 123747.0 94540.0 78782.0 111026.0 79440.0 105290.0 True False 83211.93468961916 73178.61324089153 84664.20941796908 107099.58756771339 106566.86507870456 88628.39885483551 85793.44537904322 93869.48282366923 83639.03622002575 101603.82914778168 0.8189842389560761 0.7202347968052859 0.8332777428577607 1.0540900718607582 1.0488469378816836 0.8722938849669382 0.8443918511600342 0.9238774129972707 0.8231878357495136 1.0 16.63259524848013 -5.531492843465692 24.42156412863506 0.9337247128339804 0.7713961838020692 0.44056478690488876 0.0781568601292609 133.7873211531571 379294.8059565197 0.022820928517201737 0.03961308875119234 2.9410821580562616e-06 5.531492843465692 -0.1623285290319112 AEADKIYSFTDNAPS(ph)PSIGGSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AEADKIYSFTDNAPSPSIGGSSR 23 1 O15014 O15014 ZNF609 Zinc finger protein 609 1 AEADKIYSFTDNAPS(0.886)PS(0.113)IGGS(0.001)SR;AEADKIYSFTDNAPS(0.893)PS(0.1)IGGS(0.004)S(0.003)R 159.38 1.2667e-07 23491700.0 64021.0 39169.0 50351.0 80372.0 83761.0 81791.0 75218.0 73519.0 73697.0 64192.0 True False 74858.49082761222 43057.439461097085 51551.55879723084 75869.01740953985 67348.63333336964 77501.73597517361 68092.80650883884 71589.20414981956 74774.67920397365 75829.50145640755 0.9871948171866388 0.5678191025144707 0.6798351275837745 1.0005211158239649 0.8881587250324552 1.0220525585246973 0.8979724935681354 0.9440811659690835 0.9860895531135689 1.0 16.210471617450978 -5.762031721719861 24.999998281734715 0.957037170912456 0.7272365963597367 0.46669597988968303 0.10604130924678451 12.521974392365292 528538.3872374999 0.028217612012061504 0.04487354892400406 1.7296900146533196e-06 5.762031721719861 -0.2298005745527193 AEADKIYSFTDNAPS(ph)PSIGGSSR ddPTM_PC-9_Lapatinib_30min_R1 2 AEADKIYSFTDNAPSPSIGGSSR 23 1 O15014 O15014 ZNF609 Zinc finger protein 609 1 AEADKIYSFTDNAPS(0.493)PS(0.493)IGGS(0.014)S(0.001)R;AEADKIYSFTDNAPS(0.818)PS(0.182)IGGSSR 141.82 7.1956e-08 23976000.0 159282.0 94132.0 128001.0 99893.0 99853.0 96574.0 77227.0 73474.0 110183.0 75940.0 True False 157010.6094712587 93914.04313745297 117477.25187814899 107239.46445327945 93979.84285855133 92443.75514498941 81225.43618538692 76887.87027002426 97773.03026157268 89066.12781631037 1.762854334423034 1.0544305162916807 1.3189891012263788 1.2040431877138489 1.0551692900849465 1.0379226919536129 0.9119677499947673 0.8632672392427062 1.0977577296637324 1.0 16.442589253244442 -1.5228787452803385 0.5188481985251685 0.9808621136357792 24.735768515109047 0.7069853868731726 0.13238416449624413 66.71424071527642 0.6719672383472217 0.07023932153790301 1743.0151429065882 0.029999999999999933 1.5228787452803385 23.754906401473267 AEAEAEAGS(ph)PRPDPR ddPTM_PC-9_Lapatinib_30min_R1 2 AEAEAEAGSPRPDPR 15 1 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 1 AEAEAEAGS(1)PRPDPR;AEAEAEAGS(1)PRPDPR 60.093 0.024653 9862600.0 68487.0 57708.0 65241.0 60230.0 60376.0 62941.0 59228.0 68539.0 70142.0 50020.0 True False 67510.36282102227 57574.38067156891 59877.13681754284 64659.51512139001 56824.80238378311 60249.160152637196 62294.53603517028 71723.57215392102 62241.86933199521 58665.89035253953 1.1507600483915588 0.9813944751471182 1.020646519770255 1.1021654104767376 0.9686174034401794 1.0269879105317137 1.0618527335190042 1.2225770668937994 1.0609549937445188 1.0 15.840234311806325 -7.536357504091075 24.97027436529 1.113502599342596 1.0380574758179066 0.07700624822489133 0.07267139980576552 392.9899522274163 728030.4527406311 0.03239035167222589 0.018712854028678057 2.9083220494234193e-08 7.536357504091075 -0.07544512352468935 AEAEAGS(ph)PRPDPR ddPTM_PC-9_AZD4547_30min_R2 1 AEAEAGSPRPDPR 13 1 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 1 AEAEAGS(1)PRPDPR 65.038 0.019188999999999998 14313000.0 49519.0 40903.0 63319.0 87904.0 67725.0 65293.0 52723.0 73851.0 55956.0 46586.0 True False 65265.01194081425 54124.09484823954 62479.34868810038 67639.09090326169 58322.55276859446 61210.21838828817 57415.2448620154 62439.02487715303 58913.719923561875 44955.03831967481 1.4517841465669639 1.2039605986622381 1.3898186059549185 1.504594221948624 1.2973529764086373 1.3615875033410705 1.2771704131077855 1.3889216250501173 1.3105031632856594 1.0 15.456195193875875 -12.780222125995651 0.3469142583126446 0.00041101179974271246 1.36628931167454 0.6358152136183517 0.08120717788013684 70.37395679432028 1.8236937682330687 51.1078555983943 0.06331647829705993 1.6587383055021628e-13 12.780222125995651 1.3658782998747974 AEAEAGS(ph)PRPDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEAEAGSPRPDPR 13 1 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 1 AEAEAGS(1)PRPDPR 52.599 0.043275 18294000.0 52852.0 66262.0 66605.0 71371.0 77477.0 82044.0 76554.0 77498.0 73098.0 59960.0 True False 61798.79972541766 72840.05344969792 68193.11580086924 67372.3142579039 62295.93802329815 77741.46820979245 69302.25091703617 75463.75961591829 74166.91996217046 70830.27335690113 0.8724913345177212 1.0283745917888791 0.9627679319724813 0.9511796448734118 0.8795100607532603 1.0975740248532861 0.9784269865490208 1.0654167496385316 1.0471076341673364 1.0 16.11207848967402 -6.764025883732687 24.9999999834506 1.038088739459911 0.9458496058997035 0.479138202450507 0.05126826065441207 64.6080656079766 624467.6920413577 0.017219105001891142 0.01588408712482763 1.7217659555430387e-07 6.764025883732687 -0.09223913356020752 AEAEAGS(ph)PRPDPR ddPTM_PC-9_Lapatinib_30min_R1 2 AEAEAGSPRPDPR 13 1 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 1 AEAEAGS(1)PRPDPR;AEAEAGS(1)PRPDPR 76.156 0.008283200000000001 33246000.0 166460.0 152037.0 187174.0 150935.0 171058.0 169280.0 150584.0 157192.0 187134.0 136720.0 True False 164086.2498749744 151684.96766762575 171785.27623253455 162035.26340439997 160996.70475296734 162040.28901095368 158380.50270682937 164495.7141776093 166056.99831161898 160351.8698320515 1.0232886591645871 0.9459507259035815 1.0713019836467021 1.0104981224984255 1.0040213745034043 1.0105294636144286 0.987705992282554 1.0258421953538674 1.035578808563585 1.0 17.290881651301497 AEAEAGSPRPDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEAEAGSPRPDPR 13 1 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 0 71.176 0.034355000000000004 2564700.0 36293.0 37552.0 41892.0 40365.0 52834.0 47287.0 47536.0 43023.0 43586.0 33358.0 False True 42436.68808057562 41279.914387477824 42890.864156294694 38103.4799150957 42481.556972042454 44807.18647599409 43033.0459491632 41893.69183663652 44223.362793389206 39405.541338217285 1.0769218399093174 1.0475662301698336 1.088447530466919 0.9669574029716783 1.0780604841188137 1.137078313210179 1.092055697948953 1.06314214737119 1.1222625369823147 1.0 15.266110900069572 -6.504712044590949 24.997987293877507 1.0896640446230381 1.0450444167131498 0.1282727545597413 0.04589497593278702 1328.3427985361095 1827844.5804846392 0.0138573670869156 0.015447785999095702 3.1281527758179235e-07 6.504712044590949 -0.04461962790988827 AEAEAGSPRPDPR ddPTM_PC-9_Lapatinib_30min_R1 1 AEAEAGSPRPDPR 13 1 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 0 77.597 0.020663 3426500.0 39629.0 30027.0 37288.0 33335.0 40159.0 33978.0 30663.0 34012.0 37214.0 32793.0 False True 39063.883192931426 29957.47432635338 34222.32457584246 35786.56710230015 37796.92657563179 32524.840146586575 32250.58010478872 35592.32168691052 33022.56743920717 38461.226356074134 1.015669204909846 0.7789006530630875 0.8897876593692591 0.9304582950888778 0.982728065551206 0.8456527060648436 0.8385218871133429 0.9254078733058774 0.8585937206859748 1.0 15.231117144037436 -10.726749506997812 4.406075129577801 1.0000325603959719 0.8937828628084447 0.1767344134690817 0.067033726599463 2.1160558546737928e-05 3.823461078488908e-06 0.06322241705853947 0.015328929052744444 1.876076282067254e-11 10.726749506997812 -0.10624969758752723 AEAGAGS(ph)ATEFQFR ddPTM_PC-9_AZD4547_30min_R2 2 AEAGAGSATEFQFR 14 0 P46783;Q9NQ39 P46783 RPS10;RPS10P5 40S ribosomal protein S10;Putative 40S ribosomal protein S10-like 1 AEAGAGS(0.991)AT(0.009)EFQFR;AEAGAGS(0.999)AT(0.001)EFQFR 194.77 1.4094000000000002e-07 27773000.0 45522.0 41883.0 63280.0 80912.0 60732.0 58318.0 63082.0 75936.0 49049.0 56297.0 True False 59997.049083578924 55420.86068329503 62440.86585358247 62258.98847793854 52300.41011062792 54671.366240916905 68696.17579397344 64201.83603568664 51641.63000448189 54326.059165473154 1.104388023081747 1.020152419200649 1.149372268350852 1.146024383773214 0.9627131235734354 1.0063561959168061 1.2645160876611714 1.1817871022106095 0.9505867128551568 1.0 15.729356776666632 AEAGAGS(ph)ATEFQFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AEAGAGSATEFQFR 14 0 P46783;Q9NQ39 P46783 RPS10;RPS10P5 40S ribosomal protein S10;Putative 40S ribosomal protein S10-like 1 AEAGAGS(0.956)AT(0.044)EFQFR;AEAGAGS(0.977)AT(0.023)EFQFR;AEAGAGS(0.992)AT(0.008)EFQFR;AEAGAGS(0.989)AT(0.011)EFQFR 134.81 2.9768e-05 27547800.0 56089.3 57184.7 64056.9 62308.4 77144.1 69810.0 63942.6 76352.5 62544.8 56035.9 True False 65584.1106758282 62861.61909548363 65584.25943314595 58817.46235455835 62028.2673885554 66149.04070651869 57885.494023665495 74348.32777716094 63459.39937686341 66194.76509005977 0.9907748835817944 0.9496463807970116 0.9907771308488942 0.8885515686102309 0.9370569908989672 0.9993092447192936 0.8744723838042285 1.1231753398627222 0.9586770085296803 1.0 16.014429507801935 -7.753452748524412 24.999984132231205 1.0306946384459728 0.9483502836187487 0.30870920896344567 0.05480981650591211 195.70997879057143 612622.0689140533 0.024709530739277202 0.01394767566540275 1.7641976997031334e-08 7.753452748524412 -0.08234435482722402 AEAGAGS(ph)ATEFQFR ddPTM_PC-9_Lapatinib_30min_R1 2 AEAGAGSATEFQFR 14 0 P46783;Q9NQ39 P46783 RPS10;RPS10P5 40S ribosomal protein S10;Putative 40S ribosomal protein S10-like 1 AEAGAGS(0.985)AT(0.015)EFQFR;AEAGAGS(0.986)AT(0.014)EFQFR 188.63 3.4675e-06 24819000.0 43202.0 43361.0 44697.0 37699.0 42232.0 39940.0 44149.0 35529.0 42994.0 31642.0 True False 42585.9315577235 43260.60026859189 41022.185195409525 40471.51022017736 39747.996791306585 38231.85930468741 46434.81919728395 37179.80704499132 38151.56297310883 37111.27753968523 1.1475199556841962 1.165699569957699 1.1053832666240642 1.090544785931954 1.0710490025249537 1.030195181607636 1.2512320317625423 1.0018465951551467 1.0280315177053971 1.0 15.179570045592813 -1.52288137270004 0.06527156101506436 0.8686869602511275 1.58594986339072 0.3009834901296221 0.06417163900188708 387.18351415372416 1.8840792849566492 3.883500939497678 25.887936081445975 0.029999818504825807 1.52288137270004 0.7172629031395926 AEAGEQPGT(ph)AER ddPTM_PC-9_AZD4547_30min_R2 1 AEAGEQPGTAER 12 0 P56182 P56182 RRP1 Ribosomal RNA processing protein 1 homolog A 1 AEAGEQPGT(1)AER 88.78 0.019036 0.0 8905.9 10780.0 17299.0 18170.0 15411.0 15091.0 9860.6 16526.0 12438.0 12515.0 True False 11737.790945772273 14264.424185610393 17069.603957034196 13981.187223701596 13271.448663223451 14147.357384369794 10738.174297486654 13972.286429700767 13095.447287319734 12076.853659269525 0.9719245820920412 1.1811374541796993 1.413414821329106 1.1576845773046534 1.0989160784470564 1.1714439690598606 0.8891533010540891 1.1569475646478844 1.0843426323435155 1.0 13.559957022837459 -6.701415992830272 1.7473390670915636 1.0504283174159328 1.192363356241559 0.1865063749954311 0.12301839035882597 0.6138111108770304 3.8712979614709186 0.052406068852441104 0.05005331407220141 1.988767467756365e-07 6.701415992830272 0.1419350388256262 AEAGEQPGT(ph)AER ddPTM_PC-9_Lapatinib_30min_R1 1 AEAGEQPGTAER 12 0 P56182 P56182 RRP1 Ribosomal RNA processing protein 1 homolog A 1 AEAGEQPGT(1)AER 77.192 0.039018000000000004 0.0 10043.0 7623.2 14325.0 6012.8 8552.3 10698.0 8923.1 5686.3 10193.0 6339.0 True False 9899.784978339367 7605.548948768013 13147.25379609909 6455.0013701128 8049.270528468732 10240.471478256024 9385.094456936378 5950.506256858735 9044.957002951538 7434.687703813437 1.3315670237583106 1.022981630400822 1.7683666510101743 0.8682276414652721 1.0826642421496817 1.3773909390980108 1.2623387599888733 0.800370707408002 1.216588693875084 1.0 12.86005642739409 -7.399601597351614 0.5006841430493288 0.9931598638344143 1.2829961040134232 0.10452320801101544 0.2545512237169514 2.2423875450146875 1.2315907730385751 0.25147925163265283 0.20814068150571277 3.9847254411791474e-08 7.399601597351614 0.2898362401790089 AEAPAGPALGLPS(ph)PEAESGVDR ddPTM_PC-9_AZD4547_30min_R2 2 AEAPAGPALGLPSPEAESGVDR 22 0 Q53F19 Q53F19 C17orf85 Uncharacterized protein C17orf85 1 AEAPAGPALGLPS(0.999)PEAES(0.001)GVDR;AEAPAGPALGLPS(0.996)PEAES(0.004)GVDR 147.17 6.0645e-05 55567000.0 16562.9 24379.3 22925.7 19607.8 21244.9 27207.0 24449.4 31434.0 25624.0 18820.5 True False 21829.557670278326 32259.431961804396 22621.69023861371 15087.524647490158 18295.412348667574 25505.741989036433 26625.349235236223 26576.597581460373 26978.4323275672 18161.60002351435 1.2019622523354199 1.776243938862059 1.2455780442981208 0.8307376347874582 1.007367870946391 1.404377475333308 1.466024425202824 1.4633400992781957 1.485465613857669 1.0 14.148603688142192 -6.891554445098394 19.76056077637462 1.399333265388324 1.222460458996225 0.0689063251417048 0.2613068216224798 6.471669423979036 1146.7846037305399 0.09972541546472194 0.08794977718983096 1.283646836677148e-07 6.891554445098394 -0.176872806392099 AEAPAGPALGLPS(ph)PEAESGVDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 AEAPAGPALGLPSPEAESGVDR 22 0 Q53F19 Q53F19 C17orf85 Uncharacterized protein C17orf85 1 AEAPAGPALGLPS(1)PEAESGVDR;AEAPAGPALGLPS(0.999)PEAES(0.001)GVDR;AEAPAGPALGLPS(0.992)PEAES(0.008)GVDR;AEAPAGPALGLPS(0.979)PEAES(0.021)GVDR;AEAPAGPALGLPS(1)PEAESGVDR 195.13 3.2916e-19 68150600.0 44922.0 68927.8 63989.8 47423.1 54713.3 42256.8 48439.5 34278.0 36931.0 35146.5 True False 52526.40735005699 75770.49645603939 65515.559514667926 44766.1374547646 43992.62162771038 40040.7790191551 43850.95988838965 33378.23882054313 37471.04600841227 41518.282230459095 1.2651392236917256 1.824991121632961 1.577993018858658 1.0782271098374772 1.0595963817461609 0.9644131902398397 1.0561843489810672 0.8039407467598892 0.90251917939231 1.0 15.341459134688789 -5.818761547025895 3.7081914312514654 0.9671760010844622 1.5899814760084985 0.7694338985349192 0.1450099311806584 0.09807896369775329 2.7261739490769 0.041456886736282915 0.0669425501055559 1.5178835452104513e-06 5.818761547025895 0.6228054749240363 AEAPAGPALGLPS(ph)PEAESGVDR ddPTM_PC-9_Lapatinib_30min_R1 3 AEAPAGPALGLPSPEAESGVDR 22 0 Q53F19 Q53F19 C17orf85 Uncharacterized protein C17orf85 1 AEAPAGPALGLPS(0.999)PEAES(0.001)GVDR;AEAPAGPALGLPS(0.996)PEAES(0.004)GVDR;AEAPAGPALGLPS(0.985)PEAES(0.015)GVDR 144.95 6.3273e-05 51511000.0 30946.9 40197.5 31371.600000000002 28918.100000000002 35350.4 33742.9 37076.100000000006 37421.8 39426.899999999994 29601.5 True False 30505.5915310336 40104.42515847703 28792.34814587802 31044.833541953652 33271.158973560465 32299.794825541714 38995.719043249424 39160.55344299741 34986.227338337085 34718.0798334806 0.878665861630266 1.1551452543121947 0.8293185649660249 0.894197884527455 0.9583237072194071 0.9303450818842003 1.1232107083768974 1.127958505505615 1.0077235695678621 1.0 15.083399537835284 -7.252157408109086 24.72914347895399 1.0753864053021733 0.9443170160943021 0.3111019172350693 0.08955387057776974 681.3259736380184 1815199.010404639 0.03442159448870674 0.026261514802269473 5.5955475659703256e-08 7.252157408109086 -0.13106938920787126 AEAPAGPALGLPS(ph)PEAESGVDRGEPEPMEVEEGELEIVPVRR ddPTM_PC-9_AZD4547_30min_R2 2 AEAPAGPALGLPSPEAESGVDRGEPEPMEVEEGELEIVPVRR 42 2 Q53F19 Q53F19 C17orf85 Uncharacterized protein C17orf85 1 AEAPAGPALGLPS(0.535)PEAES(0.465)GVDRGEPEPMEVEEGELEIVPVRR;AEAPAGPALGLPS(0.869)PEAES(0.131)GVDRGEPEPMEVEEGELEIVPVRR 73.892 8.309800000000001e-10 23851000.0 30198.5 20421.9 45981.1 52273.6 48524.3 39830.7 34498.6 35480.3 26459.2 34209.7 True False 39800.99483217913 27022.87980297933 45371.36057048298 40222.72913906921 41787.538535387284 37340.080032444326 37568.90856735627 29997.63489118434 27857.779294472595 33012.02881562228 1.2056512810671032 0.8185767664843214 1.3743887364175538 1.218426451876675 1.2658276402452482 1.1311052780486452 1.1380369494157698 0.9086880136548457 0.84386753234898 1.0 15.010704184341172 -7.737887787482949 4.687038230422585 0.9040127958275859 1.1661003640155683 0.3998388395814422 0.13877347989194266 0.19453619949593767 10.342308485040531 0.07385582646690839 0.03851764103417369 1.8285726196359374e-08 7.737887787482949 0.2620875681879824 AEAPAGPALGLPS(ph)PEAESGVDRGEPEPMEVEEGELEIVPVRR ddPTM_PC-9_Lapatinib_30min_R1 1 AEAPAGPALGLPSPEAESGVDRGEPEPMEVEEGELEIVPVRR 42 2 Q53F19 Q53F19 C17orf85 Uncharacterized protein C17orf85 1 AEAPAGPALGLPS(0.914)PEAES(0.086)GVDRGEPEPMEVEEGELEIVPVRR 54.086999999999996 1.4864e-05 5375700.0 9802.2 9683.5 11806.0 9951.0 12033.0 8998.8 7768.0 9718.0 14660.0 8112.8 True False 9662.41883049667 9661.078450702465 10835.356252477904 10682.829735562873 11325.242597788227 8613.94230122737 8170.189030884085 10169.533757303201 13008.83642335618 9515.086670373503 1.015484058656229 1.0153431897560667 1.1387553921306086 1.1227254260148039 1.190240613682573 0.9052930992260988 0.8586562912057399 1.0687799396475712 1.3671800241043452 1.0 13.216001082343578 -5.107656045899582 24.999999955386233 1.075156738880242 1.0153733915811263 0.03452902546837533 0.13647153555527158 120.43751001492737 27867.094193863453 0.036897436275892266 0.09762147712200335 7.804479678034491e-06 5.107656045899582 -0.05978334729911583 AEAPAGPALGLPSPEAES(ph)GVDRGEPEPMEVEEGELEIVPVRR ddPTM_PC-9_AZD4547_30min_R2 1 AEAPAGPALGLPSPEAESGVDRGEPEPMEVEEGELEIVPVRR 42 2 Q53F19 Q53F19 C17orf85 Uncharacterized protein C17orf85 1 AEAPAGPALGLPS(0.111)PEAES(0.889)GVDRGEPEPMEVEEGELEIVPVRR 47.207 0.005421199999999999 26439000.0 5875.9 5757.8 9123.0 12540.0 9313.0 8399.4 7445.4 8887.8 6305.6 7938.8 True False 7744.313973687475 7618.896250084186 9002.023059137695 9649.096741068686 8020.050704081504 7874.1841901978405 8108.026176349025 7514.394731326064 6638.901142862464 7660.8650283826555 1.0108928880740817 0.9945216658767673 1.1750661349320473 1.2595309674977764 1.0468857856610325 1.027845310030246 1.0583695374229525 0.980880710400988 0.8665994138085023 1.0 12.903291588261105 -7.578506316821432 1.310448854869578 0.9331374064498581 1.0987657446542594 0.36655122015828867 0.08155700254424895 0.530031219754617 1.7099854751015722 0.06784538097474034 0.030124954968748698 2.6393299329828776e-08 7.578506316821432 0.16562833820440126 AEAPAGPALGLPSPEAES(ph)GVDRGEPEPMEVEEGELEIVPVRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AEAPAGPALGLPSPEAESGVDRGEPEPMEVEEGELEIVPVRR 42 2 Q53F19 Q53F19 C17orf85 Uncharacterized protein C17orf85 1 AEAPAGPALGLPS(0.302)PEAES(0.698)GVDRGEPEPMEVEEGELEIVPVRR;AEAPAGPALGLPS(0.272)PEAES(0.728)GVDRGEPEPMEVEEGELEIVPVRR 57.958999999999996 3.7139e-05 21876200.0 16984.1 9408.0 14571.1 21174.4 22752.9 25084.5 18320.5 22266.1 21286.2 14375.099999999999 True False 19859.1726787343 10341.96406469405 14918.53028520447 19988.06701633102 18294.632578059285 23769.02466126152 16585.04961106623 21681.638467883047 21597.470405465992 16981.191836771006 1.1694804975779924 0.6090246293725745 0.8785325805518517 1.1770709151903542 1.077346793671111 1.3997265262495986 0.9766717065849896 1.2768031052410416 1.2718465590088273 1.0 14.051650098549766 -5.750185229234388 6.098936447423493 1.1786030375046868 0.8552002955001036 0.3473534481728885 0.1759865045713951 0.14861423334545745 20.23074799523858 0.046269696739308974 0.07653829019557407 1.7775211247875978e-06 5.750185229234388 -0.3234027420045832 AEAPAGPALGLPSPEAES(ph)GVDRGEPEPMEVEEGELEIVPVRR ddPTM_PC-9_Lapatinib_30min_R1 2 AEAPAGPALGLPSPEAESGVDRGEPEPMEVEEGELEIVPVRR 42 2 Q53F19 Q53F19 C17orf85 Uncharacterized protein C17orf85 1 AEAPAGPALGLPS(0.058)PEAES(0.942)GVDRGEPEPMEVEEGELEIVPVRR;AEAPAGPALGLPS(0.228)PEAES(0.772)GVDRGEPEPMEVEEGELEIVPVRR 64.221 6.6317e-08 18594300.0 42445.0 34142.0 37342.0 32582.0 37625.0 40713.0 23361.1 27956.0 41133.0 26353.0 True False 41839.726516540315 34062.946296678216 34271.884904288476 34978.18897036578 35411.971473596095 38971.799896638404 24570.62345125981 29254.937818395585 36500.16839030761 30908.080936834747 1.3536824431787275 1.1020725086844085 1.10883250805277 1.1316842686496422 1.1457188670485792 1.2608935500163554 0.7949579108930614 0.9465142102540237 1.1809263883092944 1.0 14.915696460505181 -7.243509031000093 24.883265657897848 0.9761424544190295 1.1725891171256413 0.4338634292653345 0.11324157001422756 777.9722227052055 1079650.4694493783 0.04362761683345888 0.03372124626056615 5.708092062729671e-08 7.243509031000093 0.19644666270661182 AEAPLPS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 AEAPLPSPK 9 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 AEAPLPS(1)PK;AEAPLPS(1)PK;AEAPLPS(1)PK;AEAPLPS(1)PK 114.71 0.0020228 766520000.0 1193190.0 1341370.0 1325790.0 1572130.0 1489820.0 1336130.0 1606810.0 1558050.0 1389560.0 1469730.0 True False 1572599.600106222 1774941.620579982 1308209.1583442027 1209699.7176663738 1282984.2091651128 1252581.5798805887 1749812.977196576 1317289.172927222 1463009.3047570344 1418275.2000509978 1.1088113224074392 1.251478994003533 0.9223944395961817 0.8529372279955794 0.9046087875744988 0.883172447657231 1.2337612454435196 0.9287965924242738 1.0315412020914052 1.0 20.435706067505834 -5.265825088744683 24.998775891441916 0.966961144168939 1.1801451636972344 0.3832849295492864 0.10675862018823491 353.2998125463476 2013838.9718290884 0.028962913720466065 0.06385640367706572 5.422192241666356e-06 5.265825088744683 0.21318401952829547 AEAPLPS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 AEAPLPSPK 9 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 AEAPLPS(1)PK;AEAPLPS(1)PK;AEAPLPS(1)PK;AEAPLPS(1)PK;AEAPLPS(1)PK;AEAPLPS(1)PK 112.64 0.0021543000000000005 365337300.0 536966.0 688083.0 692267.0 934095.0 1845518.0 1736427.0 2624370.0 2693660.0 1930904.0 1828108.0 True False 627863.738238071 756391.3328578746 708773.2707172165 881760.6855268489 1483901.9960618156 1645365.7113149678 2375770.6748065804 2622954.279168689 1959139.8180885261 2159529.5091050295 0.2907409857521584 0.35025746565109206 0.3282072635399886 0.4083114779442285 0.6871413378726123 0.761909343853724 1.1001334618442733 1.2145952477656654 0.9072067826942775 1.0 21.042285599853187 -6.651827646304972 1.2167542318541327 1.0767157922397346 0.31687011437377516 0.9244394422003913 0.09011534579485457 0.11013326918329432 0.34409798259381436 0.04319379951223184 0.043200146672938644 2.2293196994334228e-07 6.651827646304972 -0.7598456778659595 down AEAPLPS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 AEAPLPSPK 9 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 AEAPLPS(1)PK;AEAPLPS(1)PK;AEAPLPS(1)PK;AEAPLPS(1)PK 124.6 0.0014535 521700000.0 396674.0 748724.0 624710.0 835761.0 1410740.0 1769560.0 2062220.0 1893730.0 1956900.0 1741100.0 True False 391017.356018898 746990.3755794666 573348.7552503377 897225.651956966 1327763.0468215544 1693880.0438458333 2168991.661080046 1981719.6092012546 1736493.3149294474 2042046.815130078 0.19148305177028485 0.36580472594693353 0.2807716018076772 0.43937565256054767 0.6502118545881507 0.8295010825880275 1.0621654924898878 0.9704574814436951 0.850369003327102 1.0 20.96158451055546 -6.4511962290771985 1.294913724463601 0.9729328713265399 0.27631340214562494 0.9511225117205627 0.06768068651031649 0.08707399598070496 0.3011000419806514 0.029009816993754173 0.03472504758131118 3.53837429126005e-07 6.4511962290771985 -0.696619469180915 down AEAPPLEREDS(ph)GTFSLGK ddPTM_PC-9_AZD4547_30min_R2 5 AEAPPLEREDSGTFSLGK 18 1 G5E9Q4;O75569 G5E9Q4 PRKRA Interferon-inducible double-stranded RNA-dependent protein kinase activator A 1 AEAPPLEREDS(0.969)GT(0.024)FS(0.007)LGK;AEAPPLEREDS(0.726)GT(0.211)FS(0.063)LGK;AEAPPLEREDS(0.749)GT(0.158)FS(0.094)LGK;AEAPPLEREDS(0.786)GT(0.174)FS(0.04)LGK;AEAPPLEREDS(0.741)GT(0.232)FS(0.026)LGK 75.22399999999999 0.0027993000000000002 258594700.0 110940.7 107534.8 159239.1 230047.0 208395.0 178411.0 148177.9 187916.0 153424.5 151826.0 True False 146217.53489008825 142293.32114237253 157127.48548902024 177013.21834072005 179462.95140954206 167254.93196625754 161365.44604137176 158877.90008009513 161534.2058476755 146510.6179522379 0.9979995780084335 0.971215077317876 1.0724648335060836 1.2081937870088428 1.2249143025800802 1.1415891510387475 1.1013907954028048 1.0844121900563477 1.1025426559891738 1.0 17.160645698210224 -5.450767262154835 4.269125316168646 1.1316310964717191 0.987453716896459 0.4458303397100982 0.06053722006862038 0.19424912817942888 6.679248926540956 0.01705297528300813 0.03658172876947257 3.541870986366659e-06 5.450767262154835 -0.1441773795752601 AEAPPLEREDS(ph)GTFSLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AEAPPLEREDSGTFSLGK 18 1 G5E9Q4;O75569 G5E9Q4 PRKRA Interferon-inducible double-stranded RNA-dependent protein kinase activator A 1 AEAPPLEREDS(0.6)GT(0.348)FS(0.052)LGK;AEAPPLEREDS(0.977)GT(0.021)FS(0.002)LGK 103.71 0.00018192 32854000.0 50688.0 48202.0 49306.0 64594.0 69418.0 70186.0 74372.0 56492.0 52555.0 54883.0 True False 59268.477266365895 52987.176004079825 50481.64203404627 60975.00759657355 55816.041221282496 66505.32260460847 67326.9457533482 55009.144858221676 53323.5174507082 64832.85344641105 0.9141735110479982 0.8172889698257302 0.7786429155979218 0.9404955104586553 0.8609221753199312 1.0257966304009716 1.0384695748275017 0.8484763809399603 0.8224767940344299 1.0 15.984437450268327 -5.780225901272708 24.97472581839773 0.9326490202067256 0.8347605146715267 0.2523618074052765 0.0765511298046805 341.4755572496804 453955.0425851846 0.022994487576771902 0.034172001474695374 1.65872388632414e-06 5.780225901272708 -0.0978885055351989 AEAPPLEREDS(ph)GTFSLGK ddPTM_PC-9_Lapatinib_30min_R1 4 AEAPPLEREDSGTFSLGK 18 1 G5E9Q4;O75569 G5E9Q4 PRKRA Interferon-inducible double-stranded RNA-dependent protein kinase activator A 1 AEAPPLEREDS(0.657)GT(0.267)FS(0.077)LGK;AEAPPLEREDS(0.67)GT(0.242)FS(0.089)LGK;AEAPPLEREDS(0.763)GT(0.2)FS(0.037)LGK;AEAPPLEREDS(0.753)GT(0.225)FS(0.022)LGK 99.86 0.00029403 119125000.0 94191.0 117004.0 157190.0 121831.0 145164.0 138150.0 147110.0 151118.0 151148.0 152174.0 True False 92847.8190674863 116733.08442670459 144266.4449709469 130790.85815630197 136625.73892340466 132241.6465433793 154726.63598524194 158139.49396338206 134124.12058099866 178477.0731408903 0.5202226674469945 0.6540508669959819 0.8083191999515958 0.7328160186325742 0.7655086253882699 0.7409447287326779 0.866927237556727 0.8860493461731429 0.7514921565030411 1.0 17.445379234459686 -3.278891773610482 0.17151835908285204 0.9820704726586033 5.982718102648801e-25 0.7148819120480786 0.06660313190211635 19.633461878080848 0.3646776095873505 0.19389980461098985 4.445205565764755 0.0005261483664757586 3.278891773610482 -0.9820704726586033 AEAPPLEREDSGTFS(ph)LGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEAPPLEREDSGTFSLGK 18 1 G5E9Q4;O75569 G5E9Q4 PRKRA Interferon-inducible double-stranded RNA-dependent protein kinase activator A 1 AEAPPLEREDS(0.306)GT(0.06)FS(0.634)LGK 61.958999999999996 0.010404 60226000.0 49266.0 40983.0 40237.0 57196.0 66383.0 55474.0 56135.0 68528.0 56519.0 51715.0 True False 57605.76075214609 45051.52139278877 41196.40267967225 53991.4935519339 53375.7276843528 52564.845783604236 50817.48641779442 66729.21261141797 57345.483451557 61090.520124285285 0.9429574447058292 0.7374551943760494 0.6743501707934463 0.8837949561092489 0.8737153911239065 0.8604419421649049 0.831839151384029 1.0923006135102644 0.9386969260515508 1.0 15.898660903115957 -7.742976010059648 23.97546097017384 1.011624014506207 0.8247468541111279 0.5202577164712128 0.07961405291364165 114.31691720933898 148445.80770000338 0.03905203038833132 0.02248345480629201 1.8072739550410683e-08 7.742976010059648 -0.18687716039507907 AEASPS(ph)SAAVSSLIEK ddPTM_PC-9_AZD4547_30min_R2 1 AEASPSSAAVSSLIEK 16 0 P98174 P98174 FGD1 FYVE, RhoGEF and PH domain-containing protein 1 1 AEAS(0.255)PS(0.552)S(0.166)AAVS(0.02)S(0.006)LIEK 90.49799999999999 0.019247999999999998 0.0 10515.0 12656.0 17793.0 27762.0 20901.0 20543.0 12577.0 18753.0 13636.0 15330.0 True False 13858.55127441308 16746.804498430905 17557.05319426032 21361.89981862432 17999.256927521463 19258.442962501387 13696.328635122583 15855.154751069735 14356.77112155427 14793.30136608884 0.9368126107524235 1.132053223550231 1.1868245471228565 1.444025190184585 1.216716707251144 1.3018353703418857 0.9258466583070577 1.0717793384115744 0.9704913572885602 1.0 13.852656428807904 -7.264569568331783 24.87991665939991 0.9980109470930446 1.2106555741502563 0.405495123875776 0.12488348655722721 290.9567732960792 2312614.1786393644 0.05416715100806874 0.03825065058029794 5.437890168100036e-08 7.264569568331783 0.21264462705721165 AEASS(ph)PVPY(ph)LSPETNPASSTSAVNHNVNLTNVR ddPTM_PC-9_Lapatinib_30min_R1 1 AEASSPVPYLSPETNPASSTSAVNHNVNLTNVR 33 0 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 2 AEAS(0.279)S(0.712)PVPY(0.475)LS(0.273)PET(0.255)NPAS(0.003)S(0.002)TSAVNHNVNLTNVR 60.602 0.005113 3163900.0 3058.1 832.38 5101.2 2610.1 3343.1 4350.5 2782.9 3137.1 4424.8 2954.9 True False 3014.4909332131433 830.4526752512752 4681.799027201444 2802.055461038355 3146.4654307874844 4164.439256510832 2926.9849451657215 3282.8611185465993 3926.4324287903414 3465.650527843244 0.8698196511721371 0.23962389415186805 1.3509149262418672 0.8085222207278182 0.9079003798878716 1.201632773718376 0.84457013817468 0.947256825860512 1.1329568279447533 1.0 11.75891046680957 -5.259499265758335 24.99999962489212 1.0103980188239479 0.55472179611992 0.43887599165863855 0.21188914475127976 145.1988207038542 1870974.2670807904 0.05106004626177074 0.12178855309505217 5.501748506651922e-06 5.259499265758335 -0.45567622270402786 AEASS(ph)PVPYLS(ph)PETNPASSTSAVNHNVNLTNVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEASSPVPYLSPETNPASSTSAVNHNVNLTNVR 33 0 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 2 AEAS(0.175)S(0.776)PVPY(0.367)LS(0.585)PET(0.096)NPASSTSAVNHNVNLTNVR 100.69 2.6183e-08 0.0 1124.4 800.02 4537.3 4122.3 5794.3 4422.8 3704.4 4806.9 4038.9 2863.4 True False 1314.7387120877088 879.440698452013 4645.486439806075 3891.3408956769217 4658.9485097305815 4190.860582105579 3353.4924144665097 4680.723968331547 4097.9612716519 3382.5117533380717 0.38868710826806246 0.25999634667466465 1.3733836801074297 1.1504293789479685 1.3773635834769364 1.2389788676919684 0.9914207721989661 1.383801242881808 1.211514274150793 1.0 11.723879231858161 -5.25821925369784 24.974956804244805 1.2258096251913575 0.32434163178557024 0.8699569468662632 0.13783211042217328 79.08743775810643 613386.3504786907 0.03388946063753679 0.08219820814879993 5.517987931651997e-06 5.25821925369784 -0.9014679934057872 AEASS(ph)PVPYLSPETNPASSTSAVNHNVNLTNVR ddPTM_PC-9_AZD4547_30min_R2 3 AEASSPVPYLSPETNPASSTSAVNHNVNLTNVR 33 0 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 1 AEAS(0.2)S(0.613)PVPY(0.166)LS(0.016)PET(0.005)NPASSTSAVNHNVNLTNVR;AEAS(0.199)S(0.75)PVPY(0.045)LS(0.003)PET(0.003)NPASSTSAVNHNVNLTNVR;AEAS(0.217)S(0.757)PVPY(0.022)LS(0.003)PET(0.002)NPASSTSAVNHNVNLTNVR 113.38 2.1563e-22 151340000.0 44507.1 33590.9 173169.0 390470.0 263952.0 200437.0 135938.5 277594.0 156941.0 229859.0 True False 58659.43199481029 44448.50151914847 170872.66591338543 300453.17420136277 227306.82094316767 187903.64270432206 148036.76315223132 234698.2257755268 165236.58085859843 221811.7063736349 0.26445597914476304 0.2003884386709345 0.7703500807371986 1.3545415574021091 1.0247737806961208 0.8471313159090181 0.6673983333542731 1.058096660508012 0.7449407588085661 1.0 17.758975981872958 -5.347828349095582 4.121064278748051 0.9517033124230556 0.22921457424568165 0.7129950841007728 0.18042587563039675 0.11668228304023713 3.5863102831927804 0.05058529713274985 0.11519725973116392 4.489227874812655e-06 5.347828349095582 -0.7224887381773739 down AEASS(ph)PVPYLSPETNPASSTSAVNHNVNLTNVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AEASSPVPYLSPETNPASSTSAVNHNVNLTNVR 33 0 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 1 AEAS(0.235)S(0.607)PVPY(0.009)LS(0.028)PET(0.028)NPAS(0.011)S(0.028)T(0.028)S(0.028)AVNHNVNLTNVR;AEAS(0.186)S(0.8)PVPY(0.011)LS(0.002)PETNPASSTSAVNHNVNLTNVR;AEAS(0.148)S(0.723)PVPY(0.099)LS(0.029)PET(0.001)NPASSTSAVNHNVNLTNVR;AEAS(0.163)S(0.622)PVPY(0.078)LS(0.111)PET(0.027)NPASSTSAVNHNVNLTNVR 134.99 9.2669e-24 176281600.0 67576.90000000001 80487.1 222513.5 220292.2 322990.1 287353.9 224131.3 215099.2 229260.7 167539.4 True False 79016.33446538595 88477.32736728704 227819.06572714855 207949.9422309484 259702.5085088336 272284.5556263701 202899.96069390897 209453.07391644156 232613.2040188672 197912.96697883916 0.3992478899769835 0.44705169508548187 1.1511073236121359 1.0507140861224236 1.312205624892688 1.375779261878696 1.025197912957381 1.0583089987167758 1.175330790951854 1.0 17.594506613265956 -5.2544799139583525 5.875433357762899 1.1537519022044693 0.4148058108360675 0.8598103805770715 0.11634229808948963 0.05188277760490017 7.691338351595844 0.032054157289679815 0.0788192958452248 5.565703749427024e-06 5.2544799139583525 -0.7389460913684018 down AEASS(ph)PVPYLSPETNPASSTSAVNHNVNLTNVR ddPTM_PC-9_Lapatinib_30min_R1 3 AEASSPVPYLSPETNPASSTSAVNHNVNLTNVR 33 0 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 1 AEAS(0.199)S(0.754)PVPY(0.043)LS(0.004)PETNPASSTSAVNHNVNLTNVR;AEAS(0.103)S(0.494)PVPY(0.361)LS(0.034)PET(0.008)NPASSTSAVNHNVNLTNVR;AEAS(0.175)S(0.771)PVPY(0.039)LS(0.012)PET(0.003)NPASSTSAVNHNVNLTNVR 148.4 1.0585999999999998e-23 165575700.0 102424.0 67023.0 180577.0 96853.0 156729.0 158795.0 109747.0 126091.0 210919.0 99169.0 True False 100963.41497773872 66867.81236138078 165730.65610737746 103975.89271213682 147510.5083610695 152003.70801922475 115429.16266380473 131949.6481778267 187163.08114446513 116310.22951561374 0.868052753383873 0.574909125705098 1.4249018061229894 0.8939531212788027 1.2682505139521485 1.306881678870898 0.9924248550150894 1.1344629679379445 1.6091712820439406 1.0 16.827618462240544 -5.255332840771248 24.95544445305982 1.195932566221054 0.7214809174754903 0.4477057322649859 0.21412017512871553 414.56842728130897 1694194.5922363824 0.05261499930935961 0.13177363635557562 5.554783786891497e-06 5.255332840771248 -0.4744516487455638 AEASSPVPY(ph)LSPETNPASSTSAVNHNVNLTNVR ddPTM_PC-9_AZD4547_30min_R2 1 AEASSPVPYLSPETNPASSTSAVNHNVNLTNVR 33 0 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 1 AEAS(0.119)S(0.316)PVPY(0.452)LS(0.053)PET(0.053)NPAS(0.005)S(0.001)TSAVNHNVNLTNVR 73.788 1.7922e-06 132490000.0 23682.0 6086.7 67821.0 117920.0 97035.0 64989.0 43146.0 93915.0 60252.0 84644.0 True False 31212.383383799403 8054.106743094133 66921.64922654573 90735.36584583887 83563.36519602143 60925.227556345344 46985.91041512273 79402.5947020057 63436.79771310409 81680.63932362836 0.3821270700408238 0.0986048445480796 0.8193085874535609 1.110855235673837 1.0230498425083756 0.7458955764897037 0.575239258705591 0.9721103478071863 0.7766442358728363 1.0 16.317706537947075 -5.304273106998775 7.1982979658020465 0.8762852537565912 0.24088910835311653 0.7132402426621842 0.16174587450700925 0.11756916104595426 17.014472797540673 0.04473661180069206 0.09529458134794055 4.962801364934475e-06 5.304273106998775 -0.6353961454034747 AEASSPVPYLS(ph)PETNPASSTSAVNHNVNLTNVR ddPTM_PC-9_AZD4547_30min_R2 1 AEASSPVPYLSPETNPASSTSAVNHNVNLTNVR 33 0 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 1 AEASSPVPY(0.021)LS(0.488)PET(0.488)NPAS(0.001)S(0.001)TSAVNHNVNLTNVR 109.48 2.7443000000000003e-21 12605000.0 7843.0 5285.9 35886.0 54403.0 42489.0 36070.0 18880.0 43245.0 21561.0 36283.0 True False 10336.910855465698 6994.463803591653 35410.12819250413 41861.228867971295 36590.13576352612 33814.53719794699 20560.283424593654 36562.47892123986 22700.670442346098 35012.743213685695 0.2952328183021441 0.19976908866877002 1.0113497241959353 1.1955998024059047 1.0450519555184086 0.9657780023568576 0.5872228662322323 1.044262047623518 0.648354523488834 1.0 15.095592479468925 -5.260273544222543 24.9908536169322 0.9403847043970167 0.24750089074068507 0.7101074122310582 0.17626030159541783 53.04165810701096 1136966.7684087607 0.047488306495573604 0.11211924663887754 5.491948496599228e-06 5.260273544222543 -0.6928838136563317 AEASSPVPYLSPET(ph)NPASSTSAVNHNVNLTNVR ddPTM_PC-9_AZD4547_30min_R2 1 AEASSPVPYLSPETNPASSTSAVNHNVNLTNVR 33 0 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 1 AEASS(0.001)PVPY(0.125)LS(0.323)PET(0.549)NPAS(0.002)STSAVNHNVNLTNVR 101.85 7.8382e-16 14970000.0 8430.7 8081.7 37524.0 61290.0 54376.0 42063.0 23078.0 53812.0 32057.0 41283.0 True False 11111.487230546303 10693.951478742818 37026.40724225397 47160.53742106059 46826.8309980818 39432.7939605557 25131.897291990044 45496.59187674317 33751.467574337425 39837.694735567246 0.2789189310350813 0.2684380095215504 0.9294314715755039 1.183816928517088 1.1754402785830533 0.9898362398301613 0.6308572184914152 1.142048810272238 0.8472244139218222 1.0 15.281846545786038 -5.280412127784453 5.046613194553648 0.9969281924613105 0.26538662309925093 0.7687458881163722 0.15679402943647264 0.07888695179360856 6.095409253207407 0.04320111002496459 0.10147900225639479 5.243096755594495e-06 5.280412127784453 -0.7315415693620595 down AEASSPVPYLSPET(ph)NPASSTSAVNHNVNLTNVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AEASSPVPYLSPETNPASSTSAVNHNVNLTNVR 33 0 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 1 AEASSPVPY(0.083)LS(0.425)PET(0.488)NPAS(0.003)S(0.001)TSAVNHNVNLTNVR;AEAS(0.051)S(0.135)PVPY(0.07)LS(0.345)PET(0.395)NPAS(0.004)STSAVNHNVNLTNVR 101.86 7.7957e-16 20410400.0 7933.1 10132.5 32328.0 30309.0 33522.0 30965.0 31386.0 26018.0 29607.0 20000.0 True False 9276.017144132877 11138.387636640362 33098.822124622755 28610.884993103806 26953.604739690498 29341.140889232913 28412.890865037767 25335.055068349702 30039.946364058964 23625.841680087102 0.39262165851010133 0.47144934717937625 1.4009584324151252 1.2109996071470468 1.1408526775326773 1.2419088084367769 1.2026192018794997 1.0723450792317466 1.271486822388129 1.0 14.528078106388246 -5.249690891016558 24.48748975089149 1.1961513256231056 0.43203527407919257 0.8938229603755742 0.10485496161987491 151.0480240416755 314828.8531301254 0.02555839502926061 0.06636660123469522 5.627417139522694e-06 5.249690891016558 -0.7641160515439129 AEASSPVPYLSPET(ph)NPASSTSAVNHNVNLTNVR ddPTM_PC-9_Lapatinib_30min_R1 1 AEASSPVPYLSPETNPASSTSAVNHNVNLTNVR 33 0 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 1 AEASSPVPY(0.05)LS(0.203)PET(0.718)NPAS(0.02)S(0.007)T(0.001)SAVNHNVNLTNVR 95.867 3.2246000000000004e-15 7067300.0 8328.6 4323.9 8893.1 5362.6 11437.0 12338.0 5789.4 9706.8 12717.0 7200.3 True False 8209.832636721821 4313.888275209624 8161.943646358731 5756.983493109183 10764.298146007144 11810.332501282757 6089.146804248242 10157.813364415595 11284.677544053246 8444.862261203329 0.9721689215037573 0.5108299154893413 0.9664981374362541 0.6817143151709447 1.274656449455614 1.3985228101991416 0.7210474979825882 1.2028394365982453 1.3362772766462225 1.0 13.043858176996096 -6.259262704130043 24.999134143514127 1.156122011651608 0.7764972712810125 0.41232204887864066 0.21795908693374 196.55857802223755 2257475.0149663086 0.06532020962202975 0.08020416415695458 5.504746143440249e-07 6.259262704130043 -0.37962474037059546 AEDEDIVLT(ph)PDGTR ddPTM_PC-9_AZD4547_30min_R2 2 AEDEDIVLTPDGTR 14 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3;B1AP52 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 AEDEDIVLT(0.795)PDGT(0.205)R;AEDEDIVLT(0.991)PDGT(0.009)R 164.7 0.00094516 11199200.0 30488.0 36569.0 32708.0 27880.0 32315.0 45867.0 45248.0 47845.0 44101.0 38688.0 True False 40182.54981020504 48389.21410422883 32274.270548972443 21452.696741706128 27828.620047502794 42998.92923920809 49274.98434300919 40451.65461872403 46432.088826024104 37333.54489571072 1.076312199188501 1.296132318519485 0.8644844908012059 0.5746225492819688 0.7454052414588694 1.1517505063964142 1.319858172607403 1.0835203228550512 1.2437096170676982 1.0 15.188184881510889 -6.869478368462616 8.117657898430712 1.1777706724944688 0.9119349055038487 0.2853083380323306 0.19584984965627922 0.35696270188663615 24.52888577558801 0.07790188525736923 0.06873827498156222 1.3505840966876517e-07 6.869478368462616 -0.26583576699062006 AEDEDIVLT(ph)PDGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEDEDIVLTPDGTR 14 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3;B1AP52 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 AEDEDIVLT(0.972)PDGT(0.028)R 139.66 0.00025972 4468300.0 13813.0 27302.0 24652.0 15817.0 22952.0 18215.0 23926.0 14010.0 12630.0 17209.0 True False 16151.268080814225 30012.362127367876 25239.797173230632 14930.824769405874 18454.720362310592 17259.773334325113 21659.55607076066 13642.252344822025 12814.689856387498 20328.855473630945 0.7944996264922257 1.4763429336342935 1.2415749231908206 0.7344646032224004 0.9078091182382924 0.849028286748026 1.0654587071493424 0.6710782297861149 0.6303694702837425 1.0 14.311241372449864 -5.75553293087525 24.997799858195492 0.8361666414550195 1.2013596271913376 0.3621728770679147 0.201849573319006 141.43223827901633 598573.9903310431 0.05448851115357148 0.09127326867927402 1.7557677560555513e-06 5.75553293087525 0.3651929857363181 AEDEDIVLT(ph)PDGTR ddPTM_PC-9_Lapatinib_30min_R1 2 AEDEDIVLTPDGTR 14 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3;B1AP52 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 AEDEDIVLT(0.999)PDGT(0.001)R;AEDEDIVLT(0.993)PDGT(0.007)R 182.37 4.5166e-05 12864900.0 24351.0 44350.0 40075.0 36311.0 54773.0 41991.0 43326.0 47462.0 47519.0 50347.0 True False 24003.750274573522 44247.31029985589 36780.188193973554 38981.432069945084 51551.35982786124 40195.14281580191 45569.208284253844 49667.25778854954 42166.909822746406 59049.41186683939 0.40650278327417855 0.7493268586592651 0.6228713721470331 0.6601493704603015 0.8730207160083695 0.680703525150171 0.7717131609543485 0.8411135050854144 0.7140953396425992 1.0 15.849635069975951 -3.8792758610835367 0.12617162830693368 1.0531885696927035 5.9589606800006625e-22 0.5858359750980191 0.0979105842314417 35.85464192947571 0.5676824174246088 0.7212294250200542 6.412386355205471 0.00013204566221271014 3.8792758610835367 -1.0531885696927035 AEDGATPS(ph)PSNETPK ddPTM_PC-9_AZD4547_30min_R2 4 AEDGATPSPSNETPK 15 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 AEDGATPS(0.764)PS(0.236)NETPK;AEDGAT(0.001)PS(0.977)PS(0.022)NET(0.001)PK;AEDGAT(0.018)PS(0.942)PS(0.04)NETPK;AEDGAT(0.192)PS(0.807)PS(0.002)NETPK 270.74 3.5974999999999995e-62 258138700.0 413891.0 512101.0 474427.0 607485.0 583638.0 539134.0 492664.0 563818.0 471761.0 494841.0 True False 545499.7285323913 677627.6335691351 468135.7879949048 467438.7187996899 502609.93802520377 505421.8657520913 536510.141583369 476692.88334872486 496697.3233408298 477516.7672078782 1.142367694692735 1.4190656330904132 0.9803546600723038 0.9788948805565167 1.0525492978268587 1.0584379449278378 1.1235419956464254 0.9982746493615906 1.0401672934860562 1.0 18.8651918663139 -5.2740471075821995 24.97627163742388 1.0324414560709219 1.2807166708599924 0.6458784553955963 0.07451183031999656 380.5407523894293 753862.5017298431 0.0186577501898321 0.03927186914051105 5.320505450309629e-06 5.2740471075821995 0.24827521478907055 AEDGATPS(ph)PSNETPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 AEDGATPSPSNETPK 15 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 AEDGATPS(0.984)PS(0.016)NETPK;AEDGAT(0.025)PS(0.97)PS(0.005)NETPK;AEDGAT(0.001)PS(0.976)PS(0.023)NETPK;AEDGATPS(0.995)PS(0.005)NETPK;AEDGAT(0.003)PS(0.376)PS(0.311)NET(0.311)PK;AEDGAT(0.002)PS(0.969)PS(0.028)NETPK;AEDGATPS(0.71)PS(0.039)NET(0.25)PK;AEDGAT(0.031)PS(0.966)PS(0.002)NETPK 248.81 2.0592999999999996e-40 499510000.0 1501236.0 1621030.0 1518855.0 1786432.0 2156530.0 1743549.0 1977623.0 1714232.0 1690788.0 1676459.0 True False 1755365.6040374436 1781955.1453859508 1555070.2634896676 1686344.006730689 1733973.4272801394 1652114.2210974034 1790288.2326893688 1669235.2263789405 1715512.5758433659 1980387.7458578623 0.8863747050086175 0.8998011369809024 0.7852352483710425 0.8515221376509782 0.8755726907050814 0.8342377519518241 0.9040089429122646 0.8428830313004502 0.8662508538701555 1.0 20.91735149672982 -14.522874717710419 0.44850506002416607 4.145135933931531 0.8580431773213841 0.6117978713649223 0.033313639773170915 892.2313643084148 5.209018064056231 2785.842699204316 0.018095841165894196 3.000027821596373e-15 14.522874717710419 -3.287092756610147 AEDGATPS(ph)PSNETPK ddPTM_PC-9_Lapatinib_30min_R1 5 AEDGATPSPSNETPK 15 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 AEDGAT(0.048)PS(0.643)PS(0.057)NET(0.251)PK;AEDGAT(0.14)PS(0.84)PS(0.02)NETPK;AEDGATPS(0.999)PSNETPK;AEDGATPS(0.993)PS(0.007)NETPK;AEDGAT(0.001)PS(0.969)PS(0.03)NET(0.001)PK 246.75 3.1756e-40 1241199700.0 1005041.0 1375422.0 887606.0 876033.0 960986.0 898014.0 886517.0 848566.0 879892.0 679795.0 True False 990708.9310380517 1372237.2948646746 814630.4609382414 940459.389180421 904462.6928511679 859608.0345928784 932416.5124990046 887993.474202484 780789.2972864739 797296.6599801019 1.24258507625352 1.721112559155737 1.0217407168851957 1.1795601767651855 1.134411741890077 1.0781533119859448 1.169472492863917 1.1137554172428688 0.9792958336310603 1.0 19.604757099842665 -5.277284990932037 24.99223226772841 1.0965900677273297 1.4818488356684218 0.6148985746623858 0.1254771981495846 421.1405379395002 664236.848363496 0.030224812328582536 0.06324092982154386 5.2809859136808705e-06 5.277284990932037 0.38525876794109215 AEDGATPS(ph)PSNETPKK ddPTM_PC-9_Lapatinib_30min_R1 2 AEDGATPSPSNETPKK 16 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 AEDGAT(0.015)PS(0.66)PS(0.042)NET(0.282)PKK;AEDGAT(0.001)PS(0.917)PS(0.082)NET(0.001)PKK 238.12 5.0803e-37 16370900.0 93292.0 98071.0 79015.0 74239.0 97382.0 91751.0 85137.0 87072.0 81628.0 65165.0 True False 91961.63897234247 97843.92262496428 72518.69170672056 79698.78371404408 91654.18222037828 87827.0236120273 89544.97728145972 91117.68299196381 72434.19505905313 76428.68342309551 1.2032346346104026 1.2801989808370482 0.9488413048445447 1.042786296250138 1.199211841881367 1.1491369428128524 1.1716148083534914 1.192192236094826 0.9477357428502384 1.0 16.221826557943054 -8.265714140311799 24.976821457701828 0.9738678494670288 1.145114711376709 0.3846088757350703 0.08823097512896506 430.6829401059235 2516368.175336928 0.0804542843261512 0.023571065465238787 5.423577616351933e-09 8.265714140311799 0.1712468619096803 AEDGATPSPS(ph)NETPK ddPTM_PC-9_AZD4547_30min_R2 1 AEDGATPSPSNETPK 15 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 AEDGATPS(0.086)PS(0.913)NET(0.001)PK 236.31 5.9421e-32 265610000.0 405530.0 560900.0 547830.0 720620.0 638160.0 691180.0 470080.0 705120.0 507460.0 533640.0 True False 534480.1044519951 742199.9560026778 540565.4162542373 554492.1924680163 549562.4994434296 647960.4053362071 511916.2093343752 596159.9060456625 534283.2995998778 514957.42602737446 1.0379112474893855 1.4412841110543058 1.0497283638074997 1.0767728834316106 1.0671998725856138 1.258279563681372 0.9940942366508614 1.1576877541988713 1.0375290705517004 1.0 18.97409363722179 -1.5228787558830532 0.08844487044554877 0.9119906196635528 1.7209798477187122 0.13444018730094964 0.12360757873674852 304.4378900540297 1.9479091468293335 2.3842761416514944 29.89744788397473 0.02999999926759036 1.5228787558830532 0.8089892280551594 AEDGATPSPS(ph)NETPKK ddPTM_PC-9_AZD4547_30min_R2 1 AEDGATPSPSNETPKK 16 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 AEDGAT(0.003)PS(0.342)PS(0.367)NET(0.287)PKK 63.754 0.014740000000000001 46264000.0 36877.0 36342.0 45330.0 56679.0 46964.0 43473.0 35930.0 50772.0 41924.0 41125.0 True False 48603.118910749516 48088.84079345573 44728.89458190417 43612.53223182072 40443.85925764884 40754.62643765872 39127.700394367035 42926.35402449276 44140.01705045768 39685.22626747578 1.2247156809228636 1.2117567497118487 1.127091837159612 1.0989614104219831 1.0191162571446593 1.0269470599203656 0.985951299121969 1.081670890199088 1.112253127976565 1.0 15.276314410659094 -5.550865857394624 1.393961251558425 1.039183303680259 1.231962980435835 0.7887874310194593 0.03645090940187286 0.22748315920757317 0.8263247637043422 0.012528268623627888 0.04101257707794866 2.8127694897494143e-06 5.550865857394624 0.19277967675557606 AEDGATPSPS(ph)NETPKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEDGATPSPSNETPKK 16 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 AEDGAT(0.02)PS(0.232)PS(0.739)NET(0.009)PKK 50.87 0.041878 25506000.0 28842.0 35570.0 36909.0 45194.0 48236.0 41300.0 48423.0 37673.0 36817.0 37533.0 True False 33724.380944533696 39101.15452605949 37789.050538161995 42661.926700924894 38784.502065023284 39134.1552955052 43836.02288783929 36684.12366784298 37355.37897407906 44337.4357889355 0.7606299359547014 0.8818993212010979 0.8523057291371895 0.9622100588769562 0.8747574453708492 0.882643630583418 0.9886909810598171 0.8273848727399246 0.842524568897175 1.0 15.436237715348732 -3.9307156620394488 1.2355983056500706 0.9024344596795841 1.0904321158939377e-07 0.35647740302826403 0.05766110043758371 11.63805353274038 3.1705823925805348 0.016624286418606374 22.170176125297335 0.000117296306761438 3.9307156620394488 -0.9024343506363726 AEDGATPSPSNET(ph)PK ddPTM_PC-9_AZD4547_30min_R2 8 AEDGATPSPSNETPK 15 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 AEDGATPS(0.005)PS(0.005)NET(0.99)PK;AEDGATPSPSNET(1)PK;AEDGAT(0.037)PS(0.077)PS(0.045)NET(0.841)PK;AEDGATPSPSNET(1)PK;AEDGATPSPS(0.001)NET(0.999)PK;AEDGATPSPS(0.001)NET(0.999)PK;AEDGAT(0.003)PS(0.058)PS(0.004)NET(0.936)PK;AEDGATPSPSNET(1)PK 234.36 1.8978999999999998e-31 1242239900.0 420629.6 492717.0 431610.0 456853.0 540695.0 620548.0 592485.0 567714.0 592828.0 535387.0 True False 554381.0631608055 651978.134643914 425886.5693910359 351532.5991584886 465628.8323250658 581745.0354619251 645215.0172044693 479986.8460698995 624163.6777976515 516643.26408911915 1.0730442099893065 1.2619503242598165 0.8243339243799217 0.680416495467655 0.9012579175807206 1.1260091360865514 1.2488598266001432 0.929048880403294 1.208113453096304 1.0 18.978808935301416 -6.766534109624044 24.95862611612771 1.1071251856385163 0.9438727368624841 0.17608519111305998 0.16649453490115113 242.51365045819193 1188044.6575458415 0.06335224909841364 0.05756453176152015 1.7118507221333168e-07 6.766534109624044 -0.16325244877603218 AEDGATPSPSNET(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 9 AEDGATPSPSNETPK 15 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 AEDGATPSPS(0.001)NET(0.999)PK;AEDGATPS(0.281)PS(0.155)NET(0.564)PK;AEDGATPSPSNET(1)PK;AEDGATPSPSNET(0.999)PK;AEDGATPSPS(0.001)NET(0.999)PK;AEDGATPSPS(0.008)NET(0.992)PK;AEDGATPSPSNET(1)PK;AEDGAT(0.031)PS(0.04)PS(0.334)NET(0.595)PK;AEDGATPSPSNET(1)PK 239.19 7.966899999999999e-32 1333822400.0 512348.7 578247.2 490493.6 629983.0 657016.0 474933.2 582356.1 489380.9 415391.8 416683.8 True False 599079.2155619115 635651.7605133887 502188.8276313365 594687.0949424419 528278.4312288198 450026.86691988475 527191.1143149495 476535.16991692485 421466.1192309218 492225.2744728539 1.2170834100371872 1.2913838306944652 1.0202418560671291 1.2081604212203831 1.0732452367355105 0.914270132515724 1.0710362544457759 0.9681241387437239 0.8562463999482528 1.0 18.9089592127296 -5.936319912688309 0.5509754687856673 0.9391514749727315 1.2921432727057576 0.6157384912728099 0.08242366846965062 0.9361177666547466 0.49557488111911246 0.05817709200263059 0.1847240280171542 1.1579240847191196e-06 5.936319912688309 0.352991797733026 AEDGATPSPSNET(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 11 AEDGATPSPSNETPK 15 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 AEDGATPSPSNET(1)PK;AEDGATPSPS(0.002)NET(0.998)PK;AEDGATPSPSNET(1)PK;AEDGATPSPSNET(1)PK;AEDGAT(0.006)PS(0.014)PS(0.11)NET(0.87)PK;AEDGATPSPSNET(1)PK;AEDGAT(0.004)PS(0.065)PS(0.004)NET(0.928)PK;AEDGATPS(0.019)PS(0.135)NET(0.846)PK;AEDGAT(0.007)PS(0.015)PS(0.008)NET(0.969)PK;AEDGAT(0.01)PS(0.174)PS(0.012)NET(0.805)PK;AEDGATPSPSNET(1)PK 236.31 1.2905e-38 982438200.0 587692.0 692453.0 449293.9 535297.0 501738.0 413502.5 420457.1 441407.2 391198.6 356762.2 True False 579311.4043104859 690849.667622686 412354.6898666095 574664.5270784436 472226.75729486195 395817.96199640736 442226.31132560974 461916.5899482072 347137.6941641165 418428.0709142504 1.3844945991427182 1.6510595623118787 0.9854852447294686 1.3733890410909146 1.128573320291498 0.945964168062528 1.0568753438538696 1.1039330820681699 0.8296233410096819 1.0 18.67462011476527 -5.335625160543045 0.520399887171153 0.9662811964844847 1.7000364114787188 0.5557059150412955 0.15785884771600325 1.891113428286742 0.5907400221683216 0.10154511222349502 0.7910321696710161 4.6171590951841144e-06 5.335625160543045 0.733755214994234 AEDGATPSPSNET(ph)PKK ddPTM_PC-9_AZD4547_30min_R2 3 AEDGATPSPSNETPKK 16 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 AEDGATPSPS(0.008)NET(0.991)PKK;AEDGAT(0.001)PS(0.088)PS(0.02)NET(0.891)PKK;AEDGATPSPS(0.016)NET(0.984)PKK 85.054 0.010336 241859000.0 59678.0 54079.0 81128.0 88305.0 102956.0 95646.0 95802.0 92254.0 98770.0 89335.0 True False 78654.36262048718 71558.97917751626 80052.18971190653 67947.64654864995 88662.336549921 89665.24049999533 104328.19240693435 77998.26408602274 103990.78055704852 86207.40884145774 0.9123851844931192 0.8300792256628301 0.9285998823967537 0.7881880161090453 1.0284769921919132 1.0401106088792995 1.210199840234175 0.9047744867203669 1.2062858860344106 1.0 16.395524242361645 -6.410493700944156 4.795411020677587 1.0712912544441806 0.8676036373289838 0.533708252477963 0.09223864477092755 0.1740401083561273 6.180369406383207 0.027311688044528156 0.03090006721542126 3.886031342569351e-07 6.410493700944156 -0.20368761711519678 AEDGATPSPSNET(ph)PKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 AEDGATPSPSNETPKK 16 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 AEDGATPS(0.011)PS(0.029)NET(0.96)PKK;AEDGATPSPS(0.001)NET(0.999)PKK;AEDGATPS(0.001)PS(0.001)NET(0.998)PKK;AEDGATPSPS(0.002)NET(0.997)PKK;AEDGATPS(0.001)PS(0.035)NET(0.964)PKK;AEDGATPSPS(0.018)NET(0.982)PKK 137.61 4.6022e-05 474233000.0 686970.0 819136.0 682892.0 1024126.0 1170883.0 842895.0 1030856.0 860843.0 805084.0 832947.0 True False 803260.4527240236 900454.4085987684 699174.7351623309 966747.5404812881 941456.8814039443 798692.1023681572 933205.8569288667 838246.7833885518 816856.830430712 983953.6974951758 0.8163600124364205 0.915139005921753 0.7105768665153666 0.9825132452292329 0.9568101464536244 0.8117171614897795 0.9484245643921086 0.8519168996696226 0.8301781196718527 1.0 19.9082309018247 -12.101912886678337 2.148692451979076 3.246347719474343 0.8720001768323663 0.19791222760045935 0.07877010676871002 2139110.1419581533 303463.1826349692 23150625.973180633 0.019332964122797162 7.908372428407353e-13 12.101912886678337 -2.3743475426419764 AEDGATPSPSNET(ph)PKK ddPTM_PC-9_Lapatinib_30min_R1 4 AEDGATPSPSNETPKK 16 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 AEDGATPSPS(0.012)NET(0.988)PKK;AEDGATPS(0.006)PS(0.06)NET(0.934)PKK;AEDGATPS(0.058)PS(0.027)NET(0.915)PKK;AEDGATPSPS(0.366)NET(0.634)PKK 147.75 5.8683e-05 95557000.0 377160.0 489426.0 328401.0 421931.0 381314.0 349601.0 280791.0 318744.0 294890.0 268033.0 True False 371781.6292373273 488292.7641672428 301401.13744451996 452961.2132605549 358885.86021216837 334649.380189735 295328.9840590851 333554.0098721809 261676.38287063478 314362.1469184767 1.182653932357006 1.5532810452966892 0.9587704512104701 1.4408898071879532 1.1416319163427713 1.0645345932076211 0.939454660664576 1.061050171408459 0.8324042364378405 1.0 18.262067984206517 -6.732727035041643 1.9609577209309963 0.9643799448447536 1.28225502528158 0.4566475516581264 0.15762858364678134 0.2941318771854626 2.3305810363331103 0.05967660196728001 0.055865719080498054 1.8504312959657575e-07 6.732727035041643 0.31787508043682644 AEDGATPSPSNET(ph)PKKK ddPTM_PC-9_AZD4547_30min_R2 1 AEDGATPSPSNETPKKK 17 2 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 AEDGATPSPS(0.035)NET(0.964)PKKK 86.189 0.025781000000000002 16871000.0 28022.0 17432.0 31413.0 63525.0 69735.0 44420.0 38105.0 35380.0 36269.0 57110.0 True False 36932.41310619147 23066.553098660534 30996.443095110408 48880.29270146638 60053.49896371985 41642.41037795413 41496.271180833726 29912.833951519628 38186.10529536897 55110.59628293109 0.6701508529609252 0.4185502363327673 0.5624407135059553 0.8869490805456162 1.0896906042426489 0.7556153115122738 0.7529635674380463 0.5427782671403296 0.6928995124517644 1.0 15.750042116405474 -5.701129017934456 7.170269352604856 0.8040936674299936 0.5340839711123799 0.3764852141690572 0.15647067981172647 0.25905469030172723 25.196187491619355 0.04632211791557292 0.08022038843014435 1.9900820479908414e-06 5.701129017934456 -0.2700096963176136 AEDGATPSPSNET(ph)PKKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AEDGATPSPSNETPKKK 17 2 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 AEDGATPS(0.002)PS(0.055)NET(0.943)PKKK;AEDGATPSPS(0.057)NET(0.943)PKKK 97.713 0.011839 37231000.0 57892.0 18287.5 32126.0 79105.0 92286.0 80062.0 63398.0 118821.0 68682.0 53411.0 True False 67691.97218088017 20102.962142122946 32892.005678533475 74673.00331187012 74203.22078059397 75863.40777890413 57392.482478228005 115702.07465125619 69686.3443164216 63093.991498756644 1.0728750959148643 0.31861927997563927 0.5213175596789064 1.1835200395166259 1.1760742824783283 1.2023872000616593 0.9096346754248225 1.8338049614999594 1.104484637301713 1.0 15.945215002068121 -5.777871079792393 10.968955644023493 1.2232104881172332 0.6056482129781032 0.4383650593577576 0.2910492011506311 0.3211250613313598 209.95607778893228 0.08025745580746985 0.12201965973856035 1.6677422079323226e-06 5.777871079792393 -0.61756227513913 AEDGATPSPSNET(ph)PKKK ddPTM_PC-9_Lapatinib_30min_R1 3 AEDGATPSPSNETPKKK 17 2 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 AEDGATPS(0.001)PS(0.048)NET(0.951)PKKK;AEDGATPS(0.003)PS(0.224)NET(0.773)PKKK;AEDGAT(0.001)PS(0.005)PS(0.023)NET(0.971)PKKK 91.889 0.01775 37397000.0 137381.0 69333.3 94333.8 96261.1 62278.5 57142.7 39627.5 43104.4 67264.7 40031.9 True False 135421.9217474102 69172.76300367538 86578.03910299846 103340.46241161588 58615.40107424199 54698.83992713974 41679.21805115333 45107.18778434866 59688.641157307335 46951.3605758462 2.884302394786767 1.473285590774995 1.8439942536518936 2.2010110280974193 1.2484281681156706 1.1650107527507771 0.8877105485329623 0.9607216325814791 1.2712867193887825 1.0 15.518879345044793 -6.370898904460775 3.882912685722827 1.0565254245756732 2.037763752346418 0.670354298682434 0.34781597116836704 0.15128944008192524 4.046775189765495 0.10976886661482806 0.12583989360731757 4.2569749592452643e-07 6.370898904460775 0.9812383277707448 AEDGATPSPSNETPK ddPTM_PC-9_Lapatinib_30min_R1 1 AEDGATPSPSNETPK 15 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 0 128.85 0.00040091 0.0 3658.0 3744.0 4129.3 2890.0 4410.6 3601.2 3377.9 4755.5 4229.3 4388.9 False True 3605.836249204955 3735.330998030675 3789.8048935589513 3102.5402407573847 4151.177179573234 3447.185070807215 3552.7911338083627 4976.457890806276 3752.951697496609 5147.51551715835 0.700500316547959 0.7256570641855468 0.736239624907646 0.6027257674922213 0.8064428685520237 0.6696793937418201 0.6901953227660509 0.9667688954444366 0.7290802106349744 1.0 12.329660558522756 -8.528639728169859 0.5508250657087629 0.9989204662892289 0.6953961820989111 0.5066992415477203 0.08499402167990915 0.7658833393076143 0.5552985725996163 0.09034478298595536 0.040934149227516425 2.9604673232353076e-09 8.528639728169859 -0.30352428419031785 AEDGSS(ph)SKEGTSV ddPTM_PC-9_Lapatinib_30min_R1 1 AEDGSSSKEGTSV 13 1 Q9P2E9;A0A087WVV2;Q9P2E9-3;F8W7S5 Q9P2E9 RRBP1 Ribosome-binding protein 1 1 AEDGS(0.195)S(0.796)S(0.006)KEGT(0.002)S(0.002)V 101.39 0.010979000000000001 0.0 24686.0 22575.0 21364.0 16249.0 17057.0 21485.0 17538.0 16014.0 21088.0 13901.0 True False 24333.97311314205 22522.728974503865 19607.534387424854 17444.005665074994 16053.740795352262 20566.136633981198 18446.03182590695 16758.068901981223 18712.84737351535 16303.769328081815 1.49253664128018 1.381443059042208 1.2026381134853639 1.0699369767842104 0.9846643725326204 1.2614344707734444 1.1313967619828424 1.027864695872317 1.147762029562336 1.0 13.992917924513051 -5.250177704140625 1.968733770074851 1.0949753492787557 1.4894949566642435 0.7635763100100517 0.07743386544190264 0.18612305042891716 1.2849550555432994 0.022322497438901308 0.09244682966876229 5.621112740518244e-06 5.250177704140625 0.39451960738548775 AEDGSVIDYELIDQDAR ddPTM_PC-9_AZD4547_30min_R2 4 AEDGSVIDYELIDQDAR 17 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YN28;H0YNP5;H0YL33;H0YNA0 P07355 ANXA2 Annexin A2;Annexin 0 ;;; 321.78 4.057699999999999e-148 55991700.0 36636.0 42549.2 57152.0 64459.0 59827.9 52294.5 47544.0 66783.0 52567.3 52053.0 False True 48285.485923860906 56302.39680504393 56394.12713754658 49598.97343162252 51521.828789725914 49024.51664812975 51775.32389506779 56463.22187067082 55345.90015973006 50230.640313700125 0.9612755406323441 1.1208775451283222 1.122703727950794 0.9874246699199389 1.0257051964291528 0.9759882880640601 1.0307518194416956 1.1240792774698274 1.101835449719218 1.0 15.6162800453916 -10.809339292243207 4.765834624592285 0.9999796617165304 1.0511604431962038 0.057632441420260916 0.06059777842137545 1.3756054260034559e-05 2.0594982106493664e-06 0.06163315933913745 0.01494229732227725 1.5511746823798558e-11 10.809339292243207 0.05118078147967342 AEDGSVIDYELIDQDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AEDGSVIDYELIDQDAR 17 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YN28;H0YNP5;H0YL33;H0YNA0 P07355 ANXA2 Annexin A2;Annexin 0 ;;; 321.78 4.057699999999999e-148 37294000.0 48962.7 55496.8 64830.5 65609.0 78020.8 55571.0 62184.8 63182.9 56183.8 45135.1 False True 57251.118052594116 61006.15553842612 66376.30499104029 61933.14043724785 62733.184316999046 52656.75893284549 56294.20556503537 61524.415822816256 57005.381785693105 53317.73634074498 1.0737724813880232 1.1442000303341031 1.2449197874200832 1.1615860816266321 1.1765912925500337 0.9876030481925322 1.055825123656193 1.1539202532835175 1.0691635785394373 1.0 15.702327910176892 -6.7360294335090165 24.97880067328835 1.063080066525594 1.164106423166804 0.4572057586437217 0.057677537410471325 231.17495052150772 227252.01068631187 0.019958432687636782 0.0199513782805051 1.8364138795607165e-07 6.7360294335090165 0.10102635664120996 AEDGSVIDYELIDQDAR ddPTM_PC-9_Lapatinib_30min_R1 4 AEDGSVIDYELIDQDAR 17 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YN28;H0YNP5;H0YL33;H0YNA0 P07355 ANXA2 Annexin A2;Annexin 0 ;;; 347.51 5.873799999999997e-213 103344000.0 52710.5 41102.5 47099.0 45730.0 48701.9 47417.3 41976.4 43365.9 51578.5 46289.9 False True 51958.83860407813 41007.329686580095 43226.70202739762 49093.13675080801 45837.34999361941 45389.372614125044 44149.73259989736 45380.83802900131 45769.18618431628 54291.04753758539 0.9570424768118043 0.7553239723030016 0.7962031308655818 0.9042584178693752 0.8442892902717795 0.8360378860382502 0.8132046553224589 0.8358806854405306 0.8430337645010537 1.0 15.728426700268729 -8.773218462702333 6.444456331014204 0.9999999989896031 0.8392120133325875 0.4439567209697347 0.05265488175696626 40.520152712271866 1043.8336296010345 0.04914908378877472 0.01272655393311567 1.6857048537167561e-09 8.773218462702333 -0.16078798565701558 AEDNADTLALVFEAPNQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEDNADTLALVFEAPNQEK 19 0 P12004 P12004 PCNA Proliferating cell nuclear antigen 0 198.13 8.071899999999998e-59 0.0 6703.7 6050.7 6817.4 7817.9 8395.2 6439.8 8332.1 7977.3 5299.2 4306.9 False True 7838.504005889691 6651.373508316789 6979.952671133474 7379.888408973774 6750.220825447458 6102.085551380013 7542.823168819892 7767.904327648013 5376.690774898544 5087.706876598356 1.5406752385724156 1.3073421228158297 1.3719250814622943 1.450533332200925 1.3267707808592661 1.1993783642386002 1.4825585183600491 1.5267987162109542 1.0568004221370164 1.0 12.312799838173541 -8.346689754213617 6.122864657608569 1.0123599419210776 1.3914678522908301 0.6846421247675798 0.10102894570398357 0.1460382268401352 8.2659986450596 0.09904046626447022 0.025789178655888402 4.501012777174295e-09 8.346689754213617 0.37910791036975255 AEDNADTLALVFEAPNQEK ddPTM_PC-9_Lapatinib_30min_R1 4 AEDNADTLALVFEAPNQEK 19 0 P12004 P12004 PCNA Proliferating cell nuclear antigen 0 ;;; 307.07 1.4965999999999994e-137 20822400.0 129442.0 111461.0 142417.0 132690.0 126781.0 114949.0 135937.0 115379.0 124373.0 126971.0 False True 127596.1333432442 111202.91890264342 130708.02400551818 142448.46524086426 119323.99084103614 110032.89922920663 142975.1527151508 120739.92955174808 110364.80303424828 148917.76817177687 0.8568227613783593 0.7467404344548777 0.877719466321482 0.9565578841911581 0.8012743697810172 0.7388836173147821 0.9600946513664422 0.810782561638141 0.7411123896709378 1.0 17.184156374253263 -10.896280295594877 6.107586860528985 1.0000246967296424 0.8341769821597201 0.29570918766923515 0.07762602546174643 2.6427864859680616e-05 2.711307421531054e-06 0.07609154656376048 0.018452164902424677 1.2697543355862572e-11 10.896280295594877 -0.1658477145699223 AEDQTES(ph)SCESHR ddPTM_PC-9_AZD4547_30min_R2 2 AEDQTESSCESHR 13 0 Q9BU76 Q9BU76 MMTAG2 Multiple myeloma tumor-associated protein 2 1 AEDQTES(0.998)S(0.002)CESHR;AEDQT(0.003)ES(0.782)S(0.201)CES(0.014)HR 227.0 8.102e-20 13038900.0 41371.0 39590.0 65896.0 99021.0 67788.0 64499.0 57089.0 87522.0 59541.0 61766.0 True False 54526.117429742626 52386.69327535396 65022.17598431842 76193.23830919949 58376.806306053564 60465.867333806025 62169.8104039527 73997.48595548068 62688.215704639384 59603.59114010724 0.9148126209639074 0.8789184053056657 1.0909103753744298 1.2783330140309126 0.9794176020171347 1.0144668496848097 1.0430547759750446 1.241493751299958 1.0517523274274074 1.0 15.863111635806424 -5.265501235912928 23.703181371463472 1.0948233008497241 0.8968654952474439 0.3927755962485533 0.09441913390327744 151.26983202300534 882757.2225421263 0.02517420916387505 0.055770935271737224 5.426237071311561e-06 5.265501235912928 -0.19795780560228027 AEDQTES(ph)SCESHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AEDQTESSCESHR 13 0 Q9BU76 Q9BU76 MMTAG2 Multiple myeloma tumor-associated protein 2 1 AEDQTES(0.996)S(0.004)CESHR;AEDQT(0.008)ES(0.972)S(0.021)CESHR;AEDQT(0.003)ES(0.961)S(0.036)CESHR 174.18 0.00010365 8916700.0 28584.6 29032.9 36560.6 35263.8 42299.8 30994.6 34064.5 36709.7 28551.800000000003 27705.300000000003 True False 33423.40820841542 31915.094440248296 37432.34336084761 33288.08361278215 34011.457841655 29369.18861312507 30837.663954377083 35746.10927214227 28969.31606030125 32728.05157496589 1.0212465026173883 0.9751602342456758 1.1437388282985992 1.017111682818437 1.0392142582563884 0.897370518555096 0.9422395306283742 1.092216235062552 0.8851524813185107 1.0 14.998240095381352 -6.628745948790516 16.688260794554413 0.9678386561898225 1.0404371158980987 0.24190553588767416 0.06693794766922645 1.9088479818948483 290.80977318369577 0.02193448829859942 0.021934168402706816 2.3510076982931582e-07 6.628745948790516 0.07259845970827628 AEDQTES(ph)SCESHR ddPTM_PC-9_Lapatinib_30min_R1 2 AEDQTESSCESHR 13 0 Q9BU76 Q9BU76 MMTAG2 Multiple myeloma tumor-associated protein 2 1 AEDQTES(0.996)S(0.004)CESHR;AEDQTES(0.998)S(0.002)CESHR 198.61 3.7459e-07 11480000.0 33053.0 39537.0 53780.0 42282.0 54010.0 45662.0 46122.0 42830.0 52432.0 38420.0 True False 32581.658158822174 39445.45450564604 49358.415996803415 45391.55932861719 50833.237987745524 43709.1427033209 48509.9714833208 44820.03815860217 46526.55602656286 45060.84580856792 0.7230591786323518 0.8753820261879292 1.09537260366778 1.0073392656998548 1.1281021710888532 0.9700027134202169 1.076543740199769 0.9946559447421653 1.0325273569924034 1.0 15.459586773290882 -4.989708959878549 2.9964351759797534 1.03861024214847 0.7238225002381585 0.8152755388678421 0.047993013155694514 0.10219900630902952 1.7285273708790745 0.011754194116715829 0.06126231358326339 1.0239789764285443e-05 4.989708959878549 -0.31478774191031145 AEDQTES(ph)SCESHRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEDQTESSCESHRK 14 1 Q9BU76 Q9BU76 MMTAG2 Multiple myeloma tumor-associated protein 2 1 AEDQT(0.004)ES(0.873)S(0.096)CES(0.028)HRK 64.476 0.015092 17177000.0 21092.0 26747.0 30585.0 35787.0 33957.0 35562.0 39101.0 38517.0 35118.0 29163.0 True False 24662.459014010983 29402.265395235125 31314.262394258436 33781.97041301944 27303.369612364106 33697.06611667692 35397.070213274754 37505.96956213491 35631.53431327127 34450.02104581904 0.7158909708998303 0.8534759777397428 0.908976582412243 0.980608121199372 0.7925501576922179 0.978143556773429 1.0274905250767807 1.0887067242209056 1.0342964454471828 1.0 15.072217243834299 -3.1445035057446535 0.29261750449100155 1.0548500437880988 1.3740810649135038e-11 0.6596577336772669 0.06541755187428194 13.780187389649546 0.45077166416346065 0.07674883444858897 6.23097599339656 0.0007169625880376135 3.1445035057446535 -1.054850043774358 AEDQTESSCES(ph)HR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEDQTESSCESHR 13 0 Q9BU76 Q9BU76 MMTAG2 Multiple myeloma tumor-associated protein 2 1 AEDQT(0.001)ES(0.007)S(0.016)CES(0.976)HR 204.18 9.9067e-10 2052900.0 2384.9 2136.9 3893.3 3866.4 5422.7 3956.7 3521.1 4209.1 3184.8 2925.1 True False 2788.616466077888 2349.0373097198913 3986.131037422475 3649.778143037928 4360.160862177662 3749.203686627734 3187.5559174435894 4098.615584910093 3231.3716749503483 3455.397474921141 0.8070320379398697 0.6798168160881407 1.1535955172605565 1.0562542137417124 1.2618406113401381 1.0850281954070415 0.9224860354209571 1.1861488047778443 0.9351664167156615 1.0 11.7546359582612 -5.260684377667352 24.999169584963344 1.0826184768418523 0.7434244056679186 0.6128496595930113 0.1052995385121285 39.33379516206787 1302337.5352361002 0.02658165643539866 0.06240452017336866 5.486755685372968e-06 5.260684377667352 -0.33919407117393374 AEDQTESSCES(ph)HRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEDQTESSCESHRK 14 1 Q9BU76 Q9BU76 MMTAG2 Multiple myeloma tumor-associated protein 2 1 AEDQT(0.154)ES(0.114)S(0.009)CES(0.723)HRK 53.255 0.038968 6567100.0 12551.0 16366.0 16008.0 19988.0 20063.0 14352.0 17724.0 18368.0 17696.0 16785.0 True False 14675.636406450403 17990.708320874044 16389.69143067807 18868.137161970324 16131.799173450567 13599.355854747959 16045.054409352244 17885.8594625047 17954.770522457107 19827.98763001311 0.7401475470075578 0.9073390934358853 0.8265937893702041 0.9515911303782596 0.8135873127655315 0.6858666703101512 0.809212448017935 0.902051171114881 0.9055266150801625 1.0 14.27525064342371 -8.352021308485854 1.5492802099356373 0.9919976610588891 0.824784598132565 0.3727087124637921 0.07270616151015916 0.4346539092594162 2.1191784436140844 0.07263246275546077 0.02172415364200265 4.4460945234816534e-09 8.352021308485854 -0.1672130629263241 AEEAQKTES(ph)VDNEGE ddPTM_PC-9_Lapatinib_30min_R1 1 AEEAQKTESVDNEGE 15 1 Q15651 Q15651 HMGN3 High mobility group nucleosome-binding domain-containing protein 3 1 AEEAQKT(0.001)ES(0.999)VDNEGE 112.17 0.0016699999999999998 6287900.0 29986.0 37754.0 29852.0 30453.0 33762.0 35455.0 33316.0 36916.0 27956.0 28738.0 True False 29558.394141241075 37666.582932598845 27397.68379205236 32692.615208229952 31776.185538645877 33938.67229964176 35040.93946356004 38631.252128483735 24807.30089026912 33705.325009022 0.8769651125847057 1.117526174944657 0.8128592079951386 0.9699540117022762 0.942764549225983 1.0069231580041818 1.0396262149728723 1.1461468512213782 0.7360053903538648 1.0 15.040688916274663 -6.758907112724974 24.769318270856186 0.9982423722388444 0.9478081367406062 0.02356653966454969 0.12040974896273396 238.92269808013626 2337021.1434122096 0.03922307174037699 0.03747037006177142 1.7421794523769337e-07 6.758907112724974 -0.05043423549823822 AEEDEILNRS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 11 AEEDEILNRSPR 12 1 P27824;P27824-2;P27824-3 P27824 CANX Calnexin 1 AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR 177.36 0.00088688 7806479400.0 7473854.0 7090270.0 11375256.0 9657235.0 9449367.0 5613753.0 8561969.0 9405105.0 7382858.0 6924308.0 True False 9850384.1061795 9382061.119713146 11224412.672979772 7430908.6735434225 8137485.499997263 5262724.137471201 9323967.654268237 7951762.130062378 7773100.801476673 6681890.0845153285 1.4741912814469769 1.4041028812274565 1.6798259969871887 1.1120968138586829 1.2178418676558516 0.7876101029657888 1.3954087146503176 1.190046832480807 1.1633086900800906 1.0 22.671824820205842 -5.776290342487005 24.999675583240702 1.1329102023829483 1.507846326431878 0.5584333500781418 0.16096908647079283 173.56593492698372 292175.387408086 0.04496867039673617 0.06700927823737415 1.6738234868118748e-06 5.776290342487005 0.37493612404892973 AEEDEILNRS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 12 AEEDEILNRSPR 12 1 P27824;P27824-2;P27824-3 P27824 CANX Calnexin 1 AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR 188.09 3.8079e-05 6634906800.0 1921231.0 1845048.0 1994570.0 1755704.0 3037316.0 1673940.0 1773612.0 1609639.0 1573605.0 1397749.0 True False 2246457.462258071 2028212.1719425651 2042128.1132488456 1657337.5969491708 2442175.733355341 1586155.6395970455 1605602.6315211048 1567387.6818034975 1596615.9961568234 1651149.829125003 1.360541255937107 1.2283634932254328 1.2367915238382907 1.003747550776447 1.4790757872346012 0.9606370128370483 0.9724148609650797 0.9492704139600138 0.9669722080902381 1.0 20.655039608974498 -6.802162783277673 24.994668202501316 0.9668476724368885 1.244136795744209 0.6222279045255612 0.11327565414924017 103.0097529133368 63223.23836298506 0.03865603219427599 0.03409178472569919 1.5770200565450007e-07 6.802162783277673 0.2772891233073206 AEEDEILNRS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 13 AEEDEILNRSPR 12 1 P27824;P27824-2;P27824-3 P27824 CANX Calnexin 1 AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR 193.45 5.6178e-05 2453618000.0 15641404.0 15803394.0 7603753.0 4435106.0 6218958.0 6787887.0 7018429.3 4740126.0 10449646.0 2297088.6 True False 15418354.710677788 15766802.212150637 6978601.779675377 4761278.490319904 5853171.11738185 6497584.896347435 7381809.227715692 4960369.558640734 9272696.827829339 2694137.3038318334 5.722928333588819 5.8522637987773445 2.5902918050055614 1.7672738815308355 2.172558580832895 2.4117497230397325 2.739952866253939 1.8411717738311522 3.4418055882456002 1.0 21.36139194741078 -5.283382126958155 5.0056272483228526 2.261789790316056 5.825808307602288 0.8442579658818565 0.6094940905617664 0.0568589787909004 4.187076300786738 0.14991370576774338 0.3505368282118576 5.207363240797027e-06 5.283382126958155 3.564018517286232 AEEDEILNRSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEEDEILNRSPR 12 1 P27824;P27824-2;P27824-3 P27824 CANX Calnexin 0 95.477 0.012965 0.0 38254.0 37036.0 50903.0 45401.0 76756.0 46077.0 40668.0 52045.0 41569.0 31099.0 False True 44729.64664906011 40712.68931760299 52116.72057070251 42857.32916202796 61716.21279755634 43660.64100607733 36815.63262917721 50678.87389623568 42176.8679841783 36737.002520451446 1.2175638615088198 1.108220228227338 1.4186437922279913 1.166598421800182 1.6799468808920652 1.1884649810983217 1.0021403517797074 1.379504870274128 1.1480759204755067 1.0 15.16494629709024 -8.534734553775579 7.673172625284084 1.0000067414422724 1.2680999314994015 0.18452396604212273 0.17893890791202754 0.2716792214935035 140.72406653461238 0.1730788988077852 0.04474913381845548 2.919210726974718e-09 8.534734553775579 0.26809319005712906 AEEDTQFNYHR ddPTM_PC-9_Lapatinib_30min_R1 1 AEEDTQFNYHR 11 0 Q14683;G8JLG1;H0Y7K8 Q14683 SMC1A Structural maintenance of chromosomes protein 1A;Structural maintenance of chromosomes protein 0 84.18799999999999 0.010193 2394700.0 29999.0 27703.0 34471.0 23663.0 28755.0 30774.0 22345.0 24364.0 29723.0 23275.0 False True 29571.208758857156 27638.855405567254 31636.92744190799 25403.255957453955 27063.687434505144 29457.867757697783 23501.914765075304 25496.040385154894 26375.28274293421 27298.05273801194 1.0832717279383044 1.0124845046943862 1.1589444765726553 0.930588573524165 0.9914145779643672 1.079119746760484 0.8609374079034364 0.9339875129500435 0.9661964901330566 1.0 14.736510422071511 -6.1991993172523845 0.8442881938610445 0.9485339133568644 1.0768269463976823 0.2959820570308005 0.06935054694177782 0.8288063351318232 1.2538644726024408 0.03585995310710682 0.06483379575591887 6.321216757531641e-07 6.1991993172523845 0.12829303304081785 AEEEHLSS(ph)SGGLAK ddPTM_PC-9_AZD4547_30min_R2 1 AEEEHLSSSGGLAK 14 0 Q52LW3;F8VWZ8;Q52LW3-2 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 AEEEHLSS(0.89)S(0.11)GGLAK 112.12 0.00018953 9093500.0 15986.0 10122.0 56637.0 88386.0 47292.0 51867.0 25517.0 71596.0 33246.0 42764.0 True False 21069.215470543753 13393.738553501718 55885.95637404159 68009.97325008741 40726.32211934094 48623.74829071019 27787.963567020986 60532.483312408105 35003.31568694582 41266.84537634857 0.5105603609482405 0.32456414904876946 1.3542580215271733 1.6480536040456883 0.9869017548572439 1.178276358351785 0.6733726145916453 1.466855117234169 0.8482188393059822 1.0 15.332695535998372 -5.256553958835315 24.984159018252736 1.1579024465652334 0.41756218185778293 0.5207386185395472 0.2787140910308772 304.0774517266386 1555046.1434184755 0.0718209791320948 0.17775860975009003 5.539187181372607e-06 5.256553958835315 -0.7403402647074505 AEEEHLSS(ph)SGGLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AEEEHLSSSGGLAK 14 0 Q52LW3;F8VWZ8;Q52LW3-2 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 AEEEHLSS(0.569)S(0.431)GGLAK;AEEEHLSS(0.688)S(0.312)GGLAK 94.007 0.0020134 11339400.0 47247.0 59077.0 155844.0 173993.0 173762.0 180251.0 110609.0 117556.0 144178.0 97023.0 True False 55244.98392921375 64941.7741337086 159559.9120016612 164244.73630291686 139714.5834609542 170798.32024624982 100131.31478018741 114470.27956087764 146286.33049202207 114612.50186635448 0.48201533889935444 0.5666203343980298 1.3921684755448256 1.4330438096049658 1.2190169587596156 1.4902241680878026 0.8736508945328403 0.9987591030370956 1.2763557911212977 1.0 16.80640489546755 -5.2486038066465905 22.047074526878003 1.2165839955632252 0.5243169205625535 0.6694744093159408 0.19279023357552308 95.69757669230802 164370.54987816926 0.052048937749237266 0.13506505003345765 5.641520795462966e-06 5.2486038066465905 -0.6922670750006716 AEEEHLSS(ph)SGGLAK ddPTM_PC-9_Lapatinib_30min_R1 2 AEEEHLSSSGGLAK 14 0 Q52LW3;F8VWZ8;Q52LW3-2 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 AEEEHLSS(0.5)S(0.5)GGLAK;AEEEHLS(0.002)S(0.731)S(0.266)GGLAK 100.43 0.001111 10186800.0 118630.0 45844.0 220306.0 87789.0 135541.0 194521.0 94973.0 116919.0 240479.0 167340.0 True False 116938.31444592211 45737.85103464695 202193.29108575312 94245.2959155188 127568.74486385875 186201.79028059813 99890.23723354198 122351.48357379434 213393.7226638657 196264.4960334658 0.5958200123265418 0.23304189988008842 1.0302081893165047 0.48019533751763577 0.6499838098180861 0.9487288533777813 0.5089572452090841 0.6234010024560516 1.0872762367956714 1.0 17.582439689374823 -5.7434473649488025 0.11218866052970491 1.230607811507112 5.969092178180721e-11 0.27057287871674884 0.23083246988137077 45.45691813660241 1.2154977440030523 3.5584817495705345 10.44668567441871 1.8053135218862035e-06 5.7434473649488025 -1.230607811447421 AEEEHLSSS(ph)GGLAK ddPTM_PC-9_AZD4547_30min_R2 1 AEEEHLSSSGGLAK 14 0 Q52LW3;F8VWZ8;Q52LW3-2 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 AEEEHLSS(0.06)S(0.94)GGLAK 133.28 6.0325e-06 9269900.0 28883.0 22181.0 108160.0 227500.0 132970.0 135360.0 64378.0 156970.0 74557.0 99105.0 True False 38067.19319627897 29350.57447690393 106725.72772951148 175053.38983996236 114509.4107292729 126895.91780188843 70107.51728328873 132713.89331175902 78497.93080886781 95635.36411521416 0.39804515357330084 0.3069008493714167 1.1159650900783573 1.830425297791217 1.1973542610380061 1.3268723236000224 0.7330710551677156 1.3877073040875914 0.8208044329114438 1.0 16.545256577247557 -5.288940624367559 5.8193353181703955 1.2070595890809306 0.34852290236661876 0.5568263677892618 0.29351001491509365 0.11514949693999789 13.127730674628946 0.07766586700100683 0.17390225973164564 5.141139351220617e-06 5.288940624367559 -0.8585366867143118 AEEKENDTVT(ph)ISPK ddPTM_PC-9_AZD4547_30min_R2 1 AEEKENDTVTISPK 14 1 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 AEEKENDT(0.033)VT(0.737)IS(0.23)PK 66.00399999999999 0.027121 11721000.0 82628.0 82389.0 73190.0 67772.0 87408.0 83372.0 69381.0 70398.0 84121.0 87417.0 True False 108901.98523083236 109019.6330452927 72219.45277850353 52148.21246696223 75272.90797190562 78158.73566030581 75555.77459119343 59519.6066851068 88567.46432357474 84356.55743766399 1.2909723741548655 1.2923670234629208 0.8561213848949529 0.6181880111157643 0.8923183953722766 0.9265282751499418 0.8956716215811205 0.7055717835461616 1.0499179555664353 1.0 16.36421259998984 -5.26225570975036 9.791382937998563 0.8524543475410595 1.2920609362614175 0.6611506979638092 0.12090077878961497 0.04831925872013482 123.19408160763878 0.030926077984483203 0.07178759299555487 5.4669397827340114e-06 5.26225570975036 0.43960658872035796 AEEKENDTVTIS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 AEEKENDTVTISPK 14 1 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 AEEKENDTVT(0.003)IS(0.997)PK;AEEKENDTVTIS(1)PK 113.14 0.00011197 57200000.0 287900.0 242059.0 199111.0 222344.0 247908.0 237228.0 293190.0 208740.0 236446.0 246444.0 True False 379446.21130799194 320299.8380282626 196470.6580431836 171086.02598055618 213490.25340356884 222394.09565829096 319283.3420157108 176484.0293680105 248944.05284592413 237816.07057171545 1.5955448695952057 1.3468384926983876 0.8261454222621015 0.7194048138515674 0.8977116344170234 0.9351516704638602 1.3425641978195422 0.7421030418328699 1.0467923897971099 1.0 17.85948668384642 -5.0768854744536664 3.6118985377506636 0.9357187745795231 1.5612744382167767 0.6270731763257245 0.16881610840980427 0.14802354645439375 3.5933914041336816 0.04545921664112778 0.16066403609959504 8.377501717554642e-06 5.0768854744536664 0.6255556636372536 AEEKENDTVTIS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AEEKENDTVTISPK 14 1 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 AEEKENDT(0.001)VT(0.054)IS(0.945)PK;AEEKENDT(0.02)VT(0.176)IS(0.805)PK;AEEKENDTVT(0.002)IS(0.998)PK 74.793 0.008606299999999999 53828000.0 252936.0 236181.0 162278.0 276358.0 248137.0 202508.0 261052.0 203388.0 203781.0 201636.0 True False 295753.06908628315 259627.48881414885 166147.32296274247 260874.55722472435 199516.3361163584 191888.1239850403 236323.26470718943 198049.28050739926 206760.9116092238 238191.0106503028 1.2416634375866071 1.0899970074660699 0.6975381753876078 1.0952325888054781 0.8376316787591781 0.8056060699400552 0.9921586211922352 0.8314725226896278 0.8680466615626283 1.0 17.86175944122847 -5.0317563098419456 6.20897567376386 0.8904128654982862 1.2087509404965775 0.5291632284866034 0.10802625818433897 0.11081034960941738 14.286031489938631 0.025835306699961844 0.07705922482664634 9.29487792185252e-06 5.0317563098419456 0.31833807499829125 AEEKENDTVTIS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 AEEKENDTVTISPK 14 1 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 AEEKENDT(0.001)VT(0.132)IS(0.867)PK;AEEKENDTVT(0.009)IS(0.991)PK 108.96 0.00029998 73799000.0 411200.0 365120.0 286033.0 347040.0 323410.0 321405.0 323320.0 321400.0 311520.0 270507.0 True False 405336.21259515575 364274.58707290515 262516.47085930937 372562.4792915031 304387.65964852436 307659.25738164905 340059.9275830899 336333.4173283856 276433.3371489714 317263.7745220798 1.27760004496494 1.1481757966904402 0.8274391592760921 1.1742988302169834 0.9594151116276929 0.9697270287006489 1.0718523666792712 1.06010658744457 0.87130444553711 1.0 18.27532327681144 -5.020618216329857 7.392861455620793 1.0002473899274744 1.2476005203036662 0.48875483321540814 0.0943500809356936 0.11907805215471214 33.46492007390517 0.022707299071003703 0.06804628195244164 9.536341252874726e-06 5.020618216329857 0.24735313037619178 AEEKS(ph)PISINVK ddPTM_PC-9_AZD4547_30min_R2 1 AEEKSPISINVK 12 1 Q9UK58-6;Q9UK58 Q9UK58-6 CCNL1 Cyclin-L1 1 AEEKS(0.886)PIS(0.114)INVK 154.6 0.0013289 36685000.0 58046.0 51315.0 62223.0 65726.0 71720.0 61887.0 67181.0 70932.0 59832.0 74555.0 True False 76503.42056819619 67901.5702304821 61397.882364214005 50573.88615657736 61762.91597731398 58017.19610671877 73159.9788531583 59971.08925520611 62994.59737055109 71944.8521427759 1.0633619819855038 0.9438002610072806 0.8534020230157505 0.7029535074477955 0.8584758205457749 0.8064120556059045 1.0168896964020575 0.8335702620695136 0.8755956193437877 1.0 16.134603841306046 -10.140156087882884 15.320828986432835 0.9999998580044913 0.8787908032254973 0.10978812961886386 0.09830253651063171 0.0 0.0 0.09939506540280806 0.024106844312997252 7.241756404936435e-11 10.140156087882884 -0.12120905477899402 AEEKS(ph)PISINVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEEKSPISINVK 12 1 Q9UK58-6;Q9UK58 Q9UK58-6 CCNL1 Cyclin-L1 1 AEEKS(0.981)PIS(0.019)INVK 115.68 0.0034341999999999997 39097000.0 20690.0 23639.0 17858.0 27307.0 29387.0 19267.0 23917.0 22649.0 25680.0 22200.0 True False 24192.40835387291 25985.723695291534 18283.802446842143 25777.077320488497 23628.828306344607 18256.604602384956 21651.408615915014 22054.487748599156 26055.52141821307 26224.684264896692 0.9225052286427675 0.9908879524652648 0.6971981916791313 0.9829318461992946 0.9010147869720287 0.6961610831220765 0.8256117937288846 0.8409820124362911 0.9935494801395929 1.0 14.678637782963628 -8.26617764921668 23.178096322193515 0.9967748287244524 0.8555228077735013 0.25160169812859046 0.09628224319337797 219.5033882667775 1073685.3752199956 0.08392496339897729 0.02459455817919749 5.417792289546168e-09 8.26617764921668 -0.14125202095095113 AEEKS(ph)PISINVK ddPTM_PC-9_Lapatinib_30min_R1 2 AEEKSPISINVK 12 1 Q9UK58-6;Q9UK58 Q9UK58-6 CCNL1 Cyclin-L1 1 AEEKS(0.541)PIS(0.459)INVK;AEEKS(0.955)PIS(0.045)INVK 127.03 0.0011888 182194000.0 272746.0 286831.0 217243.0 238793.0 256799.0 236255.0 216963.0 228320.0 236581.0 213345.0 True False 268856.59202450945 286166.86044234433 199382.11912223054 256354.6338100957 241694.58770625922 226150.92438730426 228196.282531888 238928.5807231393 209934.7564716253 250221.39898565682 1.0744748175591523 1.1436546258729374 0.7968228134383483 1.0245112322499261 0.9659229333943322 0.9038032930199853 0.911977486565682 0.9548686950504788 0.8389960144202502 1.0 17.932845648794064 -5.241235295054344 24.99937508354905 0.9268496759567996 1.109064754430678 0.5474248267162427 0.06706045180632622 579.6108218075606 717174.7289538521 0.01618136162843863 0.042698267688122855 5.738054976837342e-06 5.241235295054344 0.1822150784738784 AEELS(ph)PAALSPLLEPIR ddPTM_PC-9_AZD4547_30min_R2 1 AEELSPAALSPLLEPIR 17 0 A0A5F9ZH52;A5YM69 A0A5F9ZH52 ARHGEF35 Rho guanine nucleotide exchange factor 35 1 AEELS(0.805)PAALS(0.195)PLLEPIR 143.88 2.0411e-08 0.0 0.0 0.0 486.21 0.0 0.0 0.0 512.08 0.0 0.0 0.0 True False 0.0 0.0 479.7625377160295 0.0 0.0 0.0 557.6541279695928 0.0 0.0 0.0 0.0 AEELS(ph)PAALSPLLEPIR ddPTM_PC-9_Lapatinib_30min_R1 1 AEELSPAALSPLLEPIR 17 0 A0A5F9ZH52;A5YM69 A0A5F9ZH52 ARHGEF35 Rho guanine nucleotide exchange factor 35 1 AEELS(0.577)PAALS(0.423)PLLEPIR 203.53 3.7205e-17 1257900.0 3649.3 2946.2 3544.8 3211.5 5248.2 4229.7 6348.7 6216.3 7216.9 6869.9 True False 3597.260312800344 2939.3782549139873 3253.360227323706 3447.684423249944 4939.511194358196 4048.8055909122754 6677.404621572327 6505.131991718857 6404.056724673886 8057.35306143365 0.44645683084418314 0.36480693256241425 0.4037753096480091 0.4278929317063457 0.6130439061930973 0.5024982224363231 0.8287342717465843 0.8073534747851046 0.7948089994128181 1.0 12.9760902583628 -7.24850181382354 0.5755024687720897 0.9660633495622549 0.3672776675203549 0.8982259511031141 0.06740112021880645 0.2379485042981694 0.16343221334729374 0.06045319852086251 0.04739192330239304 5.6428458461518204e-08 7.24850181382354 -0.5987856820419 down AEELS(ph)PAALSPSLEPIR ddPTM_PC-9_AZD4547_30min_R2 1 AEELSPAALSPSLEPIR 17 0 A0A2R8YF49;A0A2R8YFR7;Q12774;A0A5F9ZGZ6 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 AEELS(1)PAALSPSLEPIR 197.7 2.8042e-12 7892600.0 14809.0 16028.0 18824.0 30256.0 25005.0 21567.0 20425.0 25667.0 17013.0 22317.0 True False 19517.9539536646 21208.737555376953 18574.381460616907 23280.94665054021 21533.48736771802 20218.412080624414 22242.78543153206 21700.754918983992 17912.27244727213 21535.68862276614 0.9063073995707515 0.9848181744676807 0.8624930359079054 1.0810402703319686 0.9998977857134415 0.9388328571602216 1.0328337217886043 1.007664779107335 0.831748302133995 1.0 14.394441835321745 -5.740167006050703 24.999889905572886 0.9856368154056168 0.9245674592122275 0.1669373395015138 0.06775943032713465 479.5582482923813 563585.8663532081 0.01812874396760325 0.03136150414191757 1.8190012351008355e-06 5.740167006050703 -0.06106935619338927 AEELS(ph)PAALSPSLEPIR ddPTM_PC-9_Lapatinib_30min_R1 2 AEELSPAALSPSLEPIR 17 0 A0A2R8YF49;A0A2R8YFR7;Q12774;A0A5F9ZGZ6 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 AEELS(0.789)PAALS(0.2)PS(0.011)LEPIR;AEELS(1)PAALSPSLEPIR 186.96 2.5611999999999998e-08 13758900.0 27013.0 23675.0 24322.0 20041.3 26620.0 28626.0 25018.0 27368.0 30016.0 22496.3 True False 26627.789666422505 23620.18199208767 22322.339045635046 21515.204057816933 25054.26393693365 27401.73271046525 26313.30962598585 28639.61719179605 26635.281997507424 26384.755480564465 1.0092111593013269 0.8952208031447085 0.8460316815169322 0.8154407219602796 0.949573474553862 1.0385441218376994 0.9972921540003945 1.0854607772618003 1.0094951236947223 1.0 14.687416993036452 -6.580875426930643 4.089531323106267 1.0290075271494776 0.8875211068526628 0.5935367472636839 0.05247613538844782 0.15248274176036267 5.247287687836201 0.018509626559331038 0.01880748199721776 2.6249713824411926e-07 6.580875426930643 -0.1414864202968148 AEELSPAALS(ph)PLLEPIR ddPTM_PC-9_AZD4547_30min_R2 1 AEELSPAALSPLLEPIR 17 0 A0A5F9ZH52;A5YM69 A0A5F9ZH52 ARHGEF35 Rho guanine nucleotide exchange factor 35 1 AEELS(0.057)PAALS(0.943)PLLEPIR 118.53 0.0010134 0.0 0.0 0.0 0.0 0.0 539.94 420.12 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 464.97865104281794 393.8498299861795 0.0 0.0 0.0 0.0 0.0 AEELSPAALS(ph)PLLEPIR ddPTM_PC-9_Lapatinib_30min_R1 3 AEELSPAALSPLLEPIR 17 0 A0A5F9ZH52;A5YM69 A0A5F9ZH52 ARHGEF35 Rho guanine nucleotide exchange factor 35 1 AEELSPAALS(1)PLLEPIR;AEELS(0.028)PAALS(0.972)PLLEPIR;AEELS(0.005)PAALS(0.995)PLLEPIR 220.42 8.431200000000001e-23 4349600.0 17541.2 18747.5 22093.7 16900.5 34456.9 39310.8 45037.0 46931.0 45521.0 39356.0 True False 17291.059271337894 18704.09131559296 20277.241270148315 18143.419148415276 32430.21288687187 37629.56872195058 47368.79549226654 49111.58559003875 40393.945622619125 46158.63216142633 0.37460077263267827 0.40521329250357474 0.4392946740543478 0.39306665511586153 0.7025817570472339 0.8152227862895104 1.0262174868312393 1.0639740237164161 0.8751114088769594 1.0 15.49431285216444 -6.6103617106182195 1.4897054092878441 0.9956228731146347 0.3934606336683124 0.9524519568137844 0.058789752736926215 0.07480098357069799 0.34324578898731917 0.024483581394860936 0.025173086689345234 2.4526653146976097e-07 6.6103617106182195 -0.6021622394463223 down AEELSPAALS(ph)PSLEPIR ddPTM_PC-9_AZD4547_30min_R2 2 AEELSPAALSPSLEPIR 17 0 A0A2R8YF49;A0A2R8YFR7;Q12774;A0A5F9ZGZ6 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 AEELSPAALS(0.936)PS(0.064)LEPIR;AEELSPAALS(0.96)PS(0.04)LEPIR 139.49 7.7956e-05 54396000.0 40917.0 38372.0 62049.0 75898.0 57835.0 62429.0 50085.0 78117.0 61922.0 64053.0 True False 53927.75487352923 50774.99859464213 61226.18971790361 58400.88871241075 49805.60855476792 58525.30476103778 54542.467972498554 66045.81260008071 65195.070503731535 61810.523966215806 0.8724688194360702 0.8214620316500563 0.990546363130143 0.944837302209755 0.8057787793869942 0.9468501641084025 0.8824139397735926 1.0685205101348083 1.0547568006277643 1.0 15.915564874333882 -7.7594789234642 24.99999538073222 1.0462290157632643 0.8962517897440616 0.5905188997232707 0.05572698685431455 35.37118135286084 451078.48733254155 0.028230699444016825 0.015245522047866918 1.7398871336117888e-08 7.7594789234642 -0.14997722601920271 AEELSPAALS(ph)PSLEPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AEELSPAALSPSLEPIR 17 0 A0A2R8YF49;A0A2R8YFR7;Q12774;A0A5F9ZGZ6 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 AEELSPAALS(0.989)PS(0.011)LEPIR;AEELSPAALS(0.993)PS(0.007)LEPIR;AEELSPAALS(0.809)PS(0.191)LEPIR 224.64 6.476199999999999e-29 24092100.0 36352.5 33659.6 36110.6 53581.0 54465.0 58936.0 65809.0 58724.0 55307.0 48769.0 True False 42506.26025539705 37001.10263945325 36971.613654213135 50579.03028194578 43792.974230273896 55845.2924091016 59575.09510409958 57182.55722322116 56115.76024443574 57610.43364480839 0.7378222583337131 0.6422639146856628 0.6417520458561045 0.8779491332036475 0.7601569969126648 0.9693607368660059 1.0341025285698093 0.9925729352390357 0.9740555085978363 1.0 15.814042496850362 -6.436850088971167 1.0396292765367694 1.0081801155240842 0.673858265590107 0.8233858919819087 0.061280134862969564 0.20173280892204296 0.4645994419902244 0.02947272163028891 0.0374242173447842 3.657210104666578e-07 6.436850088971167 -0.3343218499339772 AEELSPAALS(ph)PSLEPIR ddPTM_PC-9_Lapatinib_30min_R1 1 AEELSPAALSPSLEPIR 17 0 A0A2R8YF49;A0A2R8YFR7;Q12774;A0A5F9ZGZ6 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 AEELS(0.008)PAALS(0.969)PS(0.023)LEPIR 153.48 2.5580999999999998e-05 16316000.0 21910.0 17663.0 18877.0 17553.0 20456.0 26961.0 26928.0 24914.0 32873.0 26874.0 True False 21597.5593821981 17622.102408711482 17325.00592732723 18843.90617509148 19252.81829804338 25807.940879160677 28322.20008028409 26071.595393028598 29170.496571963693 31519.135092645887 0.6852205594701515 0.559092194532429 0.5496662860958244 0.5978560680584215 0.6108295243969271 0.8188023181252281 0.8985716136256634 0.8271672213211104 0.9254853118977182 1.0 14.943940326314847 -6.8424380420473545 2.6537620644618 0.8976898022707747 0.5906218410786127 0.8867717048695908 0.053127141074156406 0.08710887138700918 1.2483101012494784 0.02013939719446949 0.017793437049941963 1.437348095779927e-07 6.8424380420473545 -0.30706796119216195 AEELSPAALSPS(ph)LEPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEELSPAALSPSLEPIR 17 0 A0A2R8YF49;A0A2R8YFR7;Q12774;A0A5F9ZGZ6 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 AEELSPAALS(0.397)PS(0.603)LEPIR 206.63 2.4915e-17 15645000.0 10851.0 14129.0 13036.0 14523.0 19841.0 16996.0 23511.0 21291.0 18146.0 15251.0 True False 12687.859982980903 15531.633744691999 13346.827679305308 13709.32339420128 15953.298479810244 16104.699840251986 21283.867875100466 20732.133809679202 18411.350921140744 18015.885573150434 0.7042595786626202 0.8621077038721436 0.7408366147260865 0.7609575082244449 0.8855128666883787 0.8939166367848861 1.1813944859208252 1.150769620816024 1.0219509247205523 1.0 14.136981948915672 -6.93588320905947 2.0224174515446034 1.0993722593304256 0.7809792137473113 0.7872564694730431 0.07256816127122817 0.1389511812727401 1.1540671835207774 0.030580757282433275 0.024875472516901146 1.1590890177159754e-07 6.93588320905947 -0.3183930455831143 AEELSPAALSPS(ph)LEPIR ddPTM_PC-9_Lapatinib_30min_R1 1 AEELSPAALSPSLEPIR 17 0 A0A2R8YF49;A0A2R8YFR7;Q12774;A0A5F9ZGZ6 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 AEELS(0.001)PAALS(0.3)PS(0.699)LEPIR 175.19 5.651900000000001e-06 17698000.0 24256.0 15676.0 19257.0 16080.0 24055.0 25761.0 25528.0 26435.0 31071.0 22906.0 True False 23910.10499199439 15639.703185130564 17673.763794169663 17262.576841307524 22640.13219394963 24659.26208182404 26849.714930536687 27663.26660571209 27571.456787864925 26865.271579673532 0.8900004945449708 0.5821531764065129 0.6578665598728496 0.6425610398209606 0.8427285809044017 0.9178862014736312 0.9994209383258714 1.0297035905135732 1.0262861741820506 1.0 14.713454801799498 -6.674690503317697 1.7168623795646034 1.014348077595873 0.6822351953085611 0.7706328578573245 0.07801612079454195 0.16009911864914664 0.9738902462611988 0.03141314657608392 0.030610471566194238 2.1149957386427046e-07 6.674690503317697 -0.33211288228731195 AEENTDQAS(ph)PQEDYAGFER ddPTM_PC-9_AZD4547_30min_R2 2 AEENTDQASPQEDYAGFER 19 0 Q9NU22 Q9NU22 MDN1 Midasin 1 AEENT(0.01)DQAS(0.99)PQEDYAGFER;AEENTDQAS(1)PQEDYAGFER 274.17 9.665299999999998e-92 28679000.0 142165.0 155456.0 169397.0 223744.0 198951.0 171292.0 147471.0 192232.0 162947.0 155697.0 True False 187370.5127843022 205704.11189223087 167150.6850979663 172163.27761034056 171330.08779423547 160581.08416165045 160595.6333108182 162526.9614519084 171560.04575710642 150246.0954204782 1.2470907297785525 1.3691145271798781 1.1125126721608238 1.1458752197754292 1.1403297191501163 1.0687870703877447 1.0688839058437813 1.0817383373395562 1.1418602611733708 1.0 17.19696797325541 -5.27632881618372 21.634534890703016 1.0994847676267674 1.3081025240774045 0.7411461589237202 0.050320586383617895 55.59289495687286 80777.90381963196 0.01278128533445141 0.02687758481157491 5.292625730429525e-06 5.27632881618372 0.20861775645063707 AEENTDQAS(ph)PQEDYAGFER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEENTDQASPQEDYAGFER 19 0 Q9NU22 Q9NU22 MDN1 Midasin 1 AEENT(0.001)DQAS(0.999)PQEDYAGFER 254.39 2.2299999999999998e-65 19065000.0 62778.0 65707.0 72625.0 77035.0 89108.0 81339.0 86327.0 59569.0 74037.0 69463.0 True False 73405.07547798118 72229.9567175652 74356.65543184627 72718.97870083973 71647.92706713016 77073.4396508741 78149.48160664372 58005.37686857266 75119.65106075717 82056.09203119439 0.8945719161238578 0.8802509957469862 0.9061686169940788 0.886210601806322 0.8731579251896682 0.9392774837677368 0.9523909763693653 0.7068990910086405 0.9154670811303045 1.0 16.324322826230905 AEENTDQAS(ph)PQEDYAGFER ddPTM_PC-9_Lapatinib_30min_R1 2 AEENTDQASPQEDYAGFER 19 0 Q9NU22 Q9NU22 MDN1 Midasin 1 AEENTDQAS(1)PQEDYAGFER;AEENTDQAS(1)PQEDYAGFER 161.14 5.0418e-06 22880000.0 62531.0 58219.0 69027.0 54390.0 57928.0 57300.0 57109.0 61630.0 66212.0 42864.0 True False 61639.29647321899 58084.19748246472 63351.866511925466 58390.02203972112 54520.78893082992 54849.41257282392 60065.824583516944 64493.55479137644 58754.50731672983 50272.98528731016 1.2260918288609746 1.1553759370069923 1.2601572425005096 1.1614592152429797 1.084494756363553 1.0910315402866864 1.1947932719777967 1.2828670193901497 1.1687093372503694 1.0 15.617495740580372 -11.952613676141452 1.7354323820583535 4.342044369346355e-05 1.1795624435428274 0.4390751694254912 0.06121308188189817 893885.8701518968 75071.38005670397 3497845.3470374895 0.01675959815851249 1.1152861881100891e-12 11.952613676141452 1.179519023099134 AEEQQLPPPLS(ph)PPS(ph)PSTPNHR ddPTM_PC-9_Lapatinib_30min_R1 1 AEEQQLPPPLSPPSPSTPNHR 21 0 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 2 AEEQQLPPPLS(0.962)PPS(0.714)PS(0.113)T(0.21)PNHR 63.042 0.013932 1162200.0 3645.8 2527.1 4194.8 2622.7 4979.1 4251.0 3923.4 4289.9 4600.1 3110.0 True False 3593.810223442162 2521.24865521456 3849.9197363962653 2815.582107070723 4686.239127287242 4069.1946395649984 4126.534454656365 4489.224415049906 4081.9882967995068 3647.559356185485 0.9852643569316629 0.6912152508057363 1.055478296704787 0.7719085098083721 1.2847602107804983 1.1155938100539775 1.1313138599536812 1.2307474606101028 1.1191012669546618 1.0 11.832715739755958 -6.25833899086733 24.99998628052084 1.1561102489014436 0.8755923390358399 0.5578513399767961 0.11800433786157374 188.95164226726723 1523609.3475194515 0.03290806260527643 0.04067590473796107 5.516466804371271e-07 6.25833899086733 -0.28051790986560377 AEEQQLPPPLS(ph)PPSPS(ph)TPNHR ddPTM_PC-9_AZD4547_30min_R2 1 AEEQQLPPPLSPPSPSTPNHR 21 0 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 2 AEEQQLPPPLS(0.844)PPS(0.277)PS(0.465)T(0.414)PNHR 58.858000000000004 0.027423000000000003 988310.0 4100.9 3298.4 6644.4 9545.3 6843.9 7263.1 5047.2 7959.9 4296.5 6783.7 True False 5404.900895981035 4364.543296272479 6556.290914626163 7344.778558414903 5893.742619313152 6808.937208827527 5496.391022278024 6729.8803553052885 4523.604218521404 6546.204727797582 0.8256541187949481 0.6667288112360786 1.001540768620595 1.1219903537734293 0.9003297123119544 1.0401350846719302 0.8396301751667399 1.0280583384029762 0.691027000624121 1.0 12.676443006989718 -5.267263922075288 24.98236571339951 0.9570813592103281 0.7461914613617071 0.3222785774843173 0.11974070795960892 466.2860141825457 1999980.1045705867 0.030192174583734067 0.06563545635487576 5.404258047325187e-06 5.267263922075288 -0.210889897848621 AEEQQLPPPLS(ph)PPSPSTPNHR ddPTM_PC-9_AZD4547_30min_R2 3 AEEQQLPPPLSPPSPSTPNHR 21 0 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 AEEQQLPPPLS(0.965)PPS(0.012)PS(0.012)T(0.012)PNHR;AEEQQLPPPLS(0.996)PPS(0.003)PS(0.001)TPNHR;AEEQQLPPPLS(0.987)PPS(0.006)PS(0.002)T(0.006)PNHR 89.891 0.00024115 45295000.0 20622.5 28413.8 66404.0 98570.0 86024.0 70658.0 54114.0 83612.0 55481.0 67151.0 True False 27180.026025352716 37598.00518785683 65523.439572397096 75846.20939131905 74081.05248232652 66239.74409017302 58930.04116729132 70691.68661261912 58413.61239329365 64800.06392917371 0.4194444322626041 0.5802155570240076 1.0111631933575564 1.1704650395749416 1.1432249906928627 1.0222172645164807 0.9094133183526129 1.090920013441421 0.9014437463694414 1.0 15.983707615965775 -5.191445324518606 3.2128021046543056 1.041780374169516 0.4483783056473462 0.8675360163379428 0.08403880331338437 0.08554732287764097 1.706433976552611 0.023654810607621733 0.07631527096065095 6.435090744345772e-06 5.191445324518606 -0.5934020685221697 down AEEQQLPPPLS(ph)PPSPSTPNHR ddPTM_PC-9_Lapatinib_30min_R1 2 AEEQQLPPPLSPPSPSTPNHR 21 0 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 AEEQQLPPPLS(0.991)PPS(0.008)PS(0.001)TPNHR;AEEQQLPPPLS(0.994)PPS(0.006)PSTPNHR 133.47 2.0192999999999998e-05 30077000.0 33325.0 26312.0 68671.0 33567.0 45603.0 56071.0 32714.0 48378.0 64829.0 30564.0 True False 32849.77938894347 26251.076180604476 63025.13545772573 36035.62915622942 42920.72119894758 53672.974037885 34407.77084916864 50625.818492571954 57527.27534036548 35846.94667602995 0.9163898863082077 0.732309962626691 1.7581730468516927 1.0052635579232092 1.1973326929863097 1.497281610145472 0.9598522061064785 1.4122770050712383 1.6048026589342037 1.0 15.129562619733344 -5.225655092723816 24.934840742689726 1.299177091071704 0.8243497079079669 0.3532925336684518 0.25970559379481434 615.8829254610071 429151.33605729754 0.0632613252276759 0.16736097147152998 5.947643200484467e-06 5.225655092723816 -0.47482738316373707 AEEQQLPPPLSPPS(ph)PSTPNHR ddPTM_PC-9_AZD4547_30min_R2 1 AEEQQLPPPLSPPSPSTPNHR 21 0 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 AEEQQLPPPLSPPS(0.564)PS(0.105)T(0.331)PNHR 145.16 9.212700000000001e-05 21217000.0 17631.0 22983.0 37314.0 53208.0 44064.0 40955.0 30086.0 56939.0 34407.0 46568.0 True False 23237.291252418177 30411.80529293912 36819.19197946551 40941.71765540531 37946.47420000505 38394.07737571167 32763.595715695155 48140.38587805468 36225.683776717335 44937.66849419605 0.5171005090177164 0.6767552993290468 0.8193391694146508 0.9110779225382634 0.8444246324195935 0.8543851664371612 0.7290897995726404 1.0712702169733679 0.8061318041321188 1.0 15.455637654509681 -4.967928409761391 1.4563077564823415 0.8830145621852936 0.4409882193840798 0.6349701173965349 0.09087752857013959 0.5231303184588573 1.3269906104591163 0.025722780616997905 0.3055977399625372 1.0766426755981712e-05 4.967928409761391 -0.44202634280121383 AEEQQLPPPLSPPS(ph)PSTPNHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AEEQQLPPPLSPPSPSTPNHR 21 0 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 AEEQQLPPPLSPPS(0.646)PS(0.177)T(0.177)PNHR;AEEQQLPPPLS(0.023)PPS(0.802)PS(0.106)T(0.069)PNHR;AEEQQLPPPLS(0.108)PPS(0.521)PS(0.186)T(0.186)PNHR;AEEQQLPPPLS(0.107)PPS(0.384)PS(0.126)T(0.384)PNHR 165.66 1.4089e-08 46426400.0 119279.0 154568.0 254108.0 206036.0 266009.0 219586.0 198128.0 170178.0 192934.0 157145.0 True False 139470.57883236374 169912.4895356751 260166.89842995701 194492.47089772506 213886.44601158443 208070.52360093946 179359.8815174987 165711.0078184957 195755.2947547319 185634.14454086433 0.7513196409923475 0.9153083876671817 1.401503473800239 1.04771927265197 1.1521934530988227 1.1208634279839402 0.9662009215013542 0.8926752577137937 1.0545220290098063 1.0 17.502102570835362 -7.277174893177704 22.337226898489217 0.9694057705492217 1.0765203378088593 0.060711402539622594 0.16123265533630052 573.4314614705187 814001.1530321699 0.07082032578689035 0.048010089942214514 5.2823248632152185e-08 7.277174893177704 0.10711456725963753 AEEQQLPPPLSPPS(ph)PSTPNHR ddPTM_PC-9_Lapatinib_30min_R1 2 AEEQQLPPPLSPPSPSTPNHR 21 0 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 AEEQQLPPPLSPPS(0.819)PS(0.09)T(0.09)PNHR;AEEQQLPPPLS(0.035)PPS(0.604)PS(0.181)T(0.181)PNHR 166.36 1.2796000000000001e-08 39538000.0 42364.0 42821.0 87315.0 47184.0 71703.0 70666.0 49122.0 59205.0 77163.0 49460.0 True False 41759.88159139388 42721.850605414416 80136.29774564691 50654.06876120981 67485.57051352183 67643.77991049166 51665.29680420807 61955.88043847869 68472.0903775875 58009.095098692655 0.7198850718210051 0.7364681440510392 1.3814436789491125 0.8732090834209789 1.163361890039942 1.1660892105868437 0.89064131609549 1.0680373540230417 1.1803681864213507 1.0 15.823991494015294 -5.148171722619374 10.30676012765089 1.0831544080599433 0.7246878031476017 0.5116088383419479 0.14144767962506155 0.3219887821451098 27.436942327234362 0.03414463170873697 0.09062223645036871 7.109323511932502e-06 5.148171722619374 -0.3584666049123416 AEEQQLPPPLSPPSPST(ph)PNHR ddPTM_PC-9_AZD4547_30min_R2 1 AEEQQLPPPLSPPSPSTPNHR 21 0 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 AEEQQLPPPLS(0.001)PPS(0.032)PS(0.228)T(0.739)PNHR 107.58 0.00013262 21951000.0 8902.3 6843.8 21100.0 29678.0 20090.0 16985.0 13631.0 26886.0 17607.0 19642.0 True False 11733.046220656934 9055.924512196698 20820.200213504904 22836.195620529223 17300.850278642476 15922.925264960631 14844.132593254028 22731.386478817323 18537.670074597092 18954.33955855949 0.6190163568826891 0.4777757876616271 1.0984397609413312 1.204800386211122 0.9127646059727612 0.840067532596781 0.7831521930581139 1.1992708270625116 0.9780171985061733 1.0 14.210240567939268 -5.259265655816348 24.996984316457823 0.9996283278310786 0.5483960381386577 0.6439824882293413 0.13491661983813727 120.93231753107796 1390651.5879114782 0.0375638218685593 0.08991454816700778 5.5047087305113116e-06 5.259265655816348 -0.4512322896924209 AEEVELYLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEEVELYLEK 10 0 Q8NBN3-2;Q8NBN3-3;Q8NBN3 Q8NBN3-2 TMEM87A Transmembrane protein 87A 0 75.387 0.023536 0.0 48245.0 41253.0 54620.0 59044.0 66628.0 56358.0 61877.0 63656.0 51205.0 42894.0 False True 56411.925617815315 45348.3252084209 55922.34794750354 55735.95610323078 53572.72169310002 53402.48726741122 56015.56260931443 61985.09744910715 51953.776254657285 50670.34265128281 1.1133124953593965 0.8949678023792252 1.1036504791839565 1.0999719596689905 1.057279641106665 1.05391999487612 1.105490108776604 1.223301327873256 1.025329088698041 1.0 15.62885396447138 AEEYEFLTPVEEAPK ddPTM_PC-9_Lapatinib_30min_R1 4 AEEYEFLTPVEEAPK 15 0 J3KTF8;J3QQX2;P52565;J3KRE2 J3KTF8 ARHGDIA Rho GDP-dissociation inhibitor 1 0 ;;; 228.78 6.7042e-24 24921700.0 176169.0 144169.0 169720.0 156196.0 168509.0 136584.0 169012.0 143385.0 134955.0 159332.0 False True 173656.7977545618 143835.1855382173 155766.27673814548 167683.17489458105 158597.6319214405 130742.62071285475 177762.61437793283 150047.19055267732 119754.94676084802 186872.3239034551 0.9292804527024509 0.7696976338375697 0.8335438522112021 0.8973141201005889 0.8486951337073203 0.6996360829782426 0.9512516924109711 0.8029396082760604 0.64083832351075 1.0 17.51169339384731 -6.563338165504282 24.99973130954148 0.8103622448509551 0.8524229536250744 0.025863830830579304 0.10582449810726643 639.3908592412798 395073.5088128906 0.03393651946238544 0.03393653690605844 2.733139725035464e-07 6.563338165504282 0.04206070877411927 AEFEDQDDEAR ddPTM_PC-9_AZD4547_30min_R2 2 AEFEDQDDEAR 11 0 Q14692 Q14692 BMS1 Ribosome biogenesis protein BMS1 homolog 0 ; 180.66 1.0973e-25 4495700.0 26669.0 18288.4 37097.0 37610.0 38172.0 34845.0 33881.0 38255.0 26347.0 27921.0 False True 35149.187250339746 24199.76765084576 36605.06954125078 28939.59556870761 32872.47669668196 32666.136641598634 36896.34336380602 32343.568762447227 27739.648631533433 26943.49428849096 1.3045519216619903 0.8981673791725968 1.3585865719312733 1.0740847218569305 1.2200524677574427 1.212394216274766 1.369397115635683 1.200422202708241 1.0295490382397265 1.0 14.71764934489192 -8.285285238839414 5.133109211422748 1.008371859512775 1.2018530860758816 0.2513857760453284 0.13129428607226956 0.2675465553559618 20.474768405183987 0.11274065371811043 0.03207166468016195 5.184594098362257e-09 8.285285238839414 0.1934812265631065 AEFEDQDDEAR ddPTM_PC-9_Lapatinib_30min_R1 2 AEFEDQDDEAR 11 0 Q14692 Q14692 BMS1 Ribosome biogenesis protein BMS1 homolog 0 ; 180.66 0.00070298 4749500.0 30762.0 29737.0 41478.0 30301.0 35717.0 33692.0 31772.0 24000.0 32043.0 28085.0 False True 30323.328238940117 29668.145803535852 38067.83894971017 32529.436621172834 33616.19628232377 32251.071699888027 33416.99869841003 25115.127616307553 28433.97991225116 32939.45482908982 0.9205777204351506 0.9006872140863432 1.1556912264404364 0.9875523681237467 1.020545010740017 0.9791015627680074 1.0144976251670832 0.7624633663981479 0.8632195055985038 1.0 15.007529057203966 -7.737998811574397 24.9196929375943 0.8596310441909271 0.9992129418707648 0.3001506535305578 0.08412091946694635 230.5831754747505 245133.60376086103 0.03942026191973489 0.022741545440874786 1.828105218656393e-08 7.737998811574397 0.13958189767983775 AEFGDFDIK ddPTM_PC-9_Lapatinib_30min_R1 1 AEFGDFDIK 9 0 Q8IWS0-5;Q8IWS0;Q8IWS0-3;Q8IWS0-4;A0A0D9SGE8;Q5JRC6;Q8IWS0-2 Q8IWS0-5;A0A0D9SGE8 PHF6 PHD finger protein 6 0 104.17 0.006092800000000001 0.0 14037.0 13387.0 15982.0 19488.0 17304.0 18118.0 12605.0 14387.0 17420.0 13330.0 False True 13836.829805929461 13356.003223994827 14668.021652304069 20921.212530062247 16286.21274097294 17343.135375120833 13257.625223261313 15055.472542325691 15457.976159267704 15634.072738891491 0.8850432025628748 0.8542881593975373 0.9382086099558522 1.3381805802923257 1.041712739410453 1.1093165334953226 0.8479956211462096 0.96299107684676 0.9887363591966841 1.0 13.93240603471433 -5.531943948826193 24.99673170874124 1.0425078300802573 0.8763112721970778 0.259455565647723 0.11887130625745847 269.12792635049885 742101.1868611454 0.03457937433964784 0.06000245866457255 2.9380288171229272e-06 5.531943948826193 -0.16619655788317944 AEFT(ph)SPPSLFK ddPTM_PC-9_AZD4547_30min_R2 2 AEFTSPPSLFK 11 0 Q6UN15;Q6UN15-5;Q6UN15-3;A0A0B4J203;Q6UN15-4 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 AEFT(0.603)S(0.375)PPS(0.022)LFK;AEFT(0.586)S(0.403)PPS(0.012)LFK 138.75 0.00025542 93841000.0 347650.0 320880.0 388830.0 474400.0 467910.0 425160.0 345870.0 428120.0 380090.0 387800.0 True False 458195.4684307845 424598.18484959775 383673.86014299165 365034.40940693626 402948.7732145155 398574.6779894415 376651.759961027 361963.8912188978 400180.7814308861 374223.24003713403 1.2243907363565072 1.1346120160989066 1.0252539636632931 0.9754455906338527 1.0767604202628651 1.0650719553117307 1.0064894952105379 0.9672405465330809 1.069363787751868 1.0 18.513539630143285 -5.0278724527561875 2.416560333003992 1.02266430072681 1.2287383476239044 0.7644701361841557 0.03635110494349822 0.16948479392190144 1.705174206249442 0.010135175307523408 0.058410758890419905 9.378373984326216e-06 5.0278724527561875 0.20607404689709452 AEFT(ph)SPPSLFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AEFTSPPSLFK 11 0 Q6UN15;Q6UN15-5;Q6UN15-3;A0A0B4J203;Q6UN15-4 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 AEFT(0.917)S(0.082)PPS(0.001)LFK;AEFT(0.668)S(0.247)PPS(0.085)LFK 158.06 0.0022898000000000003 63713000.0 427490.0 384290.0 410420.0 430360.0 475950.0 421260.0 445780.0 410350.0 373810.0 297260.0 True False 499855.6136876336 422439.7715158681 420205.969326517 406248.32444594544 382691.0141356627 399168.3840141531 403552.4912322854 399578.7473017641 379276.2640709581 351150.8848911343 1.4234781548182673 1.2030149707492128 1.196653596521027 1.1569053131444984 1.0898193073165874 1.1367432097968526 1.1492281768203345 1.137911833614327 1.0800948549184017 1.0 18.421731545166608 -1.5228787453063892 0.6680546919953437 1.1080402654216512 31.56938165972043 0.8204248045660614 0.044567848681710764 95.98450579859785 0.5781867983572856 0.017458993987734792 4341.016643872482 0.029999999998200414 1.5228787453063892 30.46134139429878 AEFT(ph)SPPSLFK ddPTM_PC-9_Lapatinib_30min_R1 1 AEFTSPPSLFK 11 0 Q6UN15;Q6UN15-5;Q6UN15-3;A0A0B4J203;Q6UN15-4 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 AEFT(0.738)S(0.246)PPS(0.016)LFK 159.44 0.0026680999999999996 31527000.0 362010.0 305030.0 312570.0 277690.0 332920.0 329530.0 274710.0 244530.0 329510.0 254070.0 True False 356847.6710154959 304323.72177598736 286871.7011550917 298112.24894668383 313338.30014590337 315436.7700719489 288933.13963364693 255891.75650065398 292397.113905873 297985.66097300564 1.197533028435964 1.0212696838575595 0.962703038187731 1.0004248122989035 1.0515214024821433 1.0585635867241414 0.9696209498477218 0.8587384898491309 0.981245583935534 1.0 18.184883384517363 -7.410080838077274 4.626617150037241 0.9356621050464633 1.0410208695018084 0.32397602383422675 0.06737273072119254 0.2724803047881337 9.204836734448278 0.029984312549075836 0.01958180141535291 3.889727362117141e-08 7.410080838077274 0.10535876445534509 AEFTS(ph)PPSLFK ddPTM_PC-9_Lapatinib_30min_R1 1 AEFTSPPSLFK 11 0 Q6UN15;Q6UN15-5;Q6UN15-3;A0A0B4J203;Q6UN15-4 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 AEFT(0.058)S(0.884)PPS(0.058)LFK 167.84 0.0021121 30727000.0 418880.0 343310.0 402260.0 331980.0 350740.0 358310.0 295260.0 292240.0 371230.0 284830.0 True False 412906.6943868163 342515.0867879029 369187.7355685048 356394.9166528148 330110.1627813715 342985.9165614054 310547.11808172485 305818.53727457137 329418.16817479656 334062.48598788097 1.2360163493538618 1.0253024543448097 1.1051457468406019 1.066851058115349 0.988168910391654 1.0267118606482746 0.9296078760935486 0.91545309665709 0.9860974577874245 1.0 18.349758456756668 -1.5228787463696576 0.3523087370324076 0.9523122148811923 3.8886502422757814 0.6977290088661916 0.048311251536284336 35.11316235460924 0.49339600629575164 0.04092540949458484 68.64064185573706 0.029999999924752437 1.5228787463696576 2.936338027394589 AEFTVETR ddPTM_PC-9_Lapatinib_30min_R1 1 AEFTVETR 8 0 Q60FE5;P21333-2;P21333;A0A087WWY3;F8WE98 Q60FE5 FLNA Filamin-A 0 107.01 0.010253 0.0 24755.0 32284.0 39021.0 28390.0 34195.0 43065.0 30195.0 32689.0 31453.0 28223.0 False True 24401.989160488978 32209.248381523066 35812.84400541592 30477.89530626372 32183.71732995665 41223.21033941822 31758.349354730322 34207.85027706156 27910.431925226607 33101.307945216395 0.7371910862517869 0.9730506249127765 1.0819162815163437 0.9207459522960695 0.9722793245276475 1.2453649991004525 0.9594288360837975 1.03342896098476 0.8431821477090623 1.0 15.01460060349423 -4.772870705715354 4.06464912668436 1.0117053590815888 0.7112541186111027 0.3892678003097234 0.10058703924906748 0.23511678100754296 7.469298513360988 0.02519311950632076 0.21005347641968566 1.6870552056809927e-05 4.772870705715354 -0.3004512404704861 AEGAATEEEGTPK ddPTM_PC-9_Lapatinib_30min_R1 1 AEGAATEEEGTPK 13 0 P80723;P80723-2;U3KQP0 P80723 BASP1 Brain acid soluble protein 1 0 128.88 0.00045854 2488500.0 11999.0 14363.0 13772.0 13011.0 13595.0 12316.0 15687.0 13914.0 15467.0 11271.0 False True 11827.892059652895 14329.743355960096 12639.71932145737 13967.872343423634 12795.368828798375 11789.27338999825 16499.1961029195 14560.495235554312 13724.94358526945 13219.177332336525 0.8947525070807325 1.0840117350500265 0.9561653500583812 1.0566370351395216 0.9679398730432766 0.8918310945991723 1.2481257863573287 1.1014675777089908 1.0382600399569288 1.0 13.69034477610092 -7.245777054881769 24.999197538683358 1.1054189992086272 0.9826712229869551 0.337372553293076 0.08285312089972154 928.1940272795833 1481525.7551741197 0.031016834237111605 0.023935389435427036 5.678360292866164e-08 7.245777054881769 -0.1227477762216721 AEGDSAGT(ph)AGTPGGTPAGDKVASWELR ddPTM_PC-9_AZD4547_30min_R2 1 AEGDSAGTAGTPGGTPAGDKVASWELR 27 1 Q92925-3;J3KMX2;B9EGA3;Q92925-2;Q92925 Q92925-3 SMARCD2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 1 AEGDS(0.013)AGT(0.56)AGT(0.423)PGGT(0.004)PAGDKVASWELR 62.028 0.00092922 4406300.0 24264.0 22033.0 37352.0 61992.0 54624.0 47463.0 37554.0 47298.0 32088.0 49892.0 True False 31979.447277447365 29154.73637120167 36856.688074636746 47700.702166852454 47040.40047887337 44495.13110690762 40896.233248262186 39989.18089991451 33784.106171049665 48145.29626594293 0.6642278635237939 0.6055573157169494 0.7655304034489547 0.9907655755894689 0.9770508051094673 0.9241843868013048 0.8494336190676098 0.8305937236116271 0.7017114607506922 1.0 15.555107235037054 -5.510280265642166 4.553130170911761 0.8918089704971888 0.6416367933544486 0.5992330082110661 0.08589113870459172 0.13955307105098852 7.373301409784625 0.024992939237338554 0.049842488876924995 3.0883017985478047e-06 5.510280265642166 -0.2501721771427402 AEGDSAGTAGT(ph)PGGTPAGDK ddPTM_PC-9_AZD4547_30min_R2 2 AEGDSAGTAGTPGGTPAGDK 20 0 Q92925-3;J3KMX2;B9EGA3;Q92925-2;Q92925 Q92925-3 SMARCD2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 1 AEGDS(0.028)AGT(0.018)AGT(0.631)PGGT(0.324)PAGDK;AEGDS(0.034)AGT(0.199)AGT(0.525)PGGT(0.242)PAGDK 298.42 9.501799999999997e-122 17842900.0 59486.0 65824.0 70773.0 53119.0 62286.0 85468.0 71047.0 96399.0 94087.0 77014.0 True False 78401.31061433532 87100.32074152317 69834.50377774336 40873.23523036903 53638.66403462044 80123.67244896396 77370.04536372388 81502.74957864708 99060.24673758245 74317.76330123705 1.054947123429242 1.1719986833897806 0.9396744556840146 0.5499793510293747 0.7217475560614403 1.0781227648656948 1.0410706932892317 1.0966792588776746 1.3329282574887926 1.0 16.181419461964694 -6.918194157918495 8.42885046110378 1.1163941300023006 0.8877776848620724 0.28035800846473014 0.17878099671050768 0.41259770318744515 37.7960463723534 0.07144118982348999 0.06299948392826196 1.2072739843422232e-07 6.918194157918495 -0.22861644514022816 AEGDSAGTAGT(ph)PGGTPAGDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEGDSAGTAGTPGGTPAGDK 20 0 Q92925-3;J3KMX2;B9EGA3;Q92925-2;Q92925 Q92925-3 SMARCD2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 1 AEGDSAGT(0.004)AGT(0.996)PGGTPAGDK 209.73 7.210999999999998e-73 0.0 24671.0 36031.0 27166.0 24808.0 23886.0 15901.0 27311.0 14416.0 16761.0 22027.0 True False 28847.313025538824 39607.91955941662 27813.740467628708 23418.08818862116 19205.709767085693 15067.123567889304 24723.90436548292 14037.595275014573 17006.097916303323 26020.32073436393 1.1086455589858046 1.5221918270633816 1.0689238134907493 0.8999922955482209 0.738104267166912 0.5790521847023505 0.9501767721422092 0.5394858663857943 0.6535698806296455 1.0 14.667351124811324 -5.727466559941617 2.014506446698643 0.726222777652856 1.316612114795899 0.6345713770990109 0.17004414086865136 0.18341882237940557 1.5151899357781735 0.0491875502066753 0.10023659784098662 1.872981294365365e-06 5.727466559941617 0.5903893371430429 AEGDSAGTAGT(ph)PGGTPAGDK ddPTM_PC-9_Lapatinib_30min_R1 2 AEGDSAGTAGTPGGTPAGDK 20 0 Q92925-3;J3KMX2;B9EGA3;Q92925-2;Q92925 Q92925-3 SMARCD2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 1 AEGDS(0.041)AGT(0.003)AGT(0.951)PGGT(0.005)PAGDK;AEGDS(0.014)AGT(0.121)AGT(0.731)PGGT(0.135)PAGDK 269.0 2.7348999999999993e-137 7004400.0 20340.5 40292.0 44563.0 34272.0 51700.0 45675.0 50450.0 47574.0 43833.0 43082.0 True False 20050.440740009144 40198.706349533095 40899.20215815457 36792.477208040524 48659.107646110795 43721.58672362538 53062.05414625413 49784.46171742567 38896.065958047155 50528.66629684345 0.39681317971501073 0.7955623865742986 0.8094257211912511 0.728150570844158 0.9630000396260322 0.8652828172184844 1.0501376354271386 0.9852716362025913 0.7697821614673612 1.0 15.624814480100538 -4.469719675034783 0.768363593833676 0.9313213430195006 2.872668964418064e-28 0.6901076594407758 0.10008801911134377 2.473706144442851 0.8022494552081186 0.038773529698845226 2.2097214810504218 3.390629411857534e-05 4.469719675034783 -0.9313213430195006 AEGDSAGTAGT(ph)PGGTPAGDKVASWELR ddPTM_PC-9_Lapatinib_30min_R1 1 AEGDSAGTAGTPGGTPAGDKVASWELR 27 1 Q92925-3;J3KMX2;B9EGA3;Q92925-2;Q92925 Q92925-3 SMARCD2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 1 AEGDS(0.025)AGT(0.245)AGT(0.663)PGGT(0.067)PAGDKVASWELR 71.857 0.00010392 4299900.0 41050.0 33564.0 38553.0 33967.0 36126.0 32830.0 25629.0 25137.0 35093.0 29753.0 True False 40464.619472351944 33486.284620166014 35383.32115888365 36465.04649059034 34001.13970644871 31425.937430467886 26955.94421633989 26304.956787130133 31140.45679432732 34895.766406619514 1.159585349146424 0.9596088026831207 1.013971745070246 1.0449705005955434 0.9743628871838992 0.9005659043071361 0.7724703307054036 0.7538151327761136 0.8923849509842021 1.0 15.09076439722616 -6.7494978417463285 2.2505415886511004 0.8346949018109653 1.0349757838184 0.5283462384541646 0.0800646909544407 0.22129295525165898 2.3021292123251462 0.03018830268803845 0.028060974423239852 1.7803367563269375e-07 6.7494978417463285 0.20028088200743466 AEGDVAALNR ddPTM_PC-9_Lapatinib_30min_R1 2 AEGDVAALNR 10 0 A0A2R8YGX3;A0A2R8Y5V9;P67936;A0A2R8YH90 A0A2R8YGX3 TPM4 Tropomyosin alpha-4 chain 0 ; 116.37 0.0048195 11067900.0 39468.0 50924.0 52209.0 51530.0 51557.0 47343.0 46527.0 38575.0 50028.0 44421.0 False True 38905.17908245525 50806.08860676125 47916.57755256807 55319.68809904082 48524.518624961966 45318.25025192329 48935.940401640575 40367.33532496099 44393.3198218051 52099.110662738065 0.7467532283671153 0.9751814946641383 0.919719683177598 1.0618163610728608 0.931388616959009 0.8698469067022955 0.9392855229031802 0.7748181266716365 0.8520936203534037 1.0 15.668971125308353 -6.735993936259899 7.599893948371112 0.8763595504598231 0.9369261563147664 0.03318762899670358 0.09150760649819369 0.49027054050511604 109.26365822337755 0.030557799379371982 0.029917439480469394 1.8365639857854685e-07 6.735993936259899 0.060566605854943334 AEGDVAALNRR ddPTM_PC-9_AZD4547_30min_R2 2 AEGDVAALNRR 11 1 A0A2R8YGX3;A0A2R8Y5V9;P67936;A0A2R8YH90 A0A2R8YGX3 TPM4 Tropomyosin alpha-4 chain 0 ; 90.149 0.0056285 12118500.0 100634.0 86888.0 171331.0 250137.0 209476.0 163305.0 128130.0 178534.0 145401.0 195017.0 False True 132633.51868276647 114972.84681255245 169059.03899431322 192471.7792281257 180393.8732189601 153093.51253425915 139533.3217792998 150945.6726031825 153086.60001797517 188189.51418855466 0.7047869763342691 0.6109418333337984 0.8983446273469102 1.022755067188709 0.9585755826874403 0.8135071350514704 0.7414510972141398 0.802093959666339 0.8134704033753525 1.0 17.52182671860517 -5.265173393033846 24.97671271124203 0.8746063065574186 0.657864397026664 0.4979806912153528 0.08952569604559492 270.309680015148 1808106.3887175233 0.02604843715961493 0.05782522575699098 5.4303348088622825e-06 5.265173393033846 -0.21674190953075456 AEGDVAALNRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEGDVAALNRR 11 1 A0A2R8YGX3;A0A2R8Y5V9;P67936;A0A2R8YH90 A0A2R8YGX3 TPM4 Tropomyosin alpha-4 chain 0 86.344 0.006940899999999999 4404400.0 30844.0 21485.0 44718.0 38022.0 42448.0 52616.0 35803.0 33919.0 40335.0 32731.0 False True 36065.280003231295 23617.88881058162 45784.24671395938 35891.75060898718 34130.61911551763 49856.72433482573 32411.480648727047 33028.66219015118 40924.82306867696 38664.87120154656 0.9327660711769995 0.6108358330607067 1.1841303304827264 0.9282780336159906 0.882729414449787 1.2894579184019501 0.8382668722670055 0.854229205057589 1.0584497451278205 1.0 15.238735786772818 -5.2572816262438105 24.99940980722428 0.9964137845867334 0.7718009699492862 0.2643186406295974 0.15478591331190408 471.3526789943267 2834086.273461315 0.03885750936203575 0.09534030836123018 5.529913954806975e-06 5.2572816262438105 -0.2246128146374472 AEGDVAALNRR ddPTM_PC-9_Lapatinib_30min_R1 1 AEGDVAALNRR 11 1 A0A2R8YGX3;A0A2R8Y5V9;P67936;A0A2R8YH90 A0A2R8YGX3 TPM4 Tropomyosin alpha-4 chain 0 66.92 0.025942000000000003 4926800.0 70599.0 50193.0 60434.0 50787.0 52120.0 54435.0 41752.0 34171.0 59146.0 37544.0 False True 69592.24531372904 50076.78119234872 55465.34980198625 54522.04540046548 49054.40407186254 52106.941944182734 43913.71426589503 35758.709407368566 52484.354645008476 44033.430375764576 1.5804411493689055 1.1372446063141681 1.2596190968694925 1.2381966368551132 1.1140264034223744 1.1833495936955598 0.9972812449802814 0.8120809371928854 1.1919206429552938 1.0 15.426311619766256 -1.522878745280735 0.3052037224060619 0.9838415049907403 5.325445090020499 0.5863424197091036 0.12361322153244621 39.96280785227809 0.5702178705727263 0.12382183159984636 95.28469160883672 0.02999999999997254 1.522878745280735 4.341603585029759 AEGEAEEESDFDVFPS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 AEGEAEEESDFDVFPSSPR 19 0 B1AL69;Q7L3B6 B1AL69 CDC37L1 Hsp90 co-chaperone Cdc37-like 1 1 AEGEAEEESDFDVFPS(0.5)S(0.5)PR 155.2 4.4096e-16 0.0 6209.7 6918.2 9523.4 14946.0 9181.4 10599.0 8320.6 11904.0 9976.0 9859.2 True False 8184.255430216163 9154.372857225408 9397.113493520977 11500.43061339813 7906.721092500151 9936.24285447852 9061.11728086196 10064.51032670688 10503.310993592357 9514.032408906927 0.8602299296935502 0.9621969385615283 0.9877108979283599 1.2087861507210718 0.8310588773166223 1.0443776547551302 0.9523950404435291 1.0578595798438317 1.1039809979792878 1.0 13.215841224413754 -4.870863060645153 2.12200978978517 1.0229271892845255 0.8351202508811402 0.22811000499829925 0.09282839855209671 0.8383774490027748 5.045847034890506 0.02443569142922447 0.285084432647263 1.3462847902755263e-05 4.870863060645153 -0.18780693840338536 AEGEAEEESDFDVFPSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEGEAEEESDFDVFPSSPR 19 0 B1AL69;Q7L3B6 B1AL69 CDC37L1 Hsp90 co-chaperone Cdc37-like 1 1 AEGEAEEESDFDVFPS(0.124)S(0.876)PR 170.91 6.202999999999999e-28 0.0 4635.9 3916.3 5544.1 7461.0 10201.0 9015.2 8471.7 12357.0 9631.5 7091.5 True False 5420.66630680132 4305.084382074973 5676.292370116337 7042.984358888364 8202.187278491218 8542.42704164743 7669.199246203418 12032.641843323743 9772.342466492175 8377.132813716888 0.6470789502018413 0.5139090519163956 0.6775936942078632 0.8407392499920783 0.9791162992021315 1.0197315992961085 0.9154921399414505 1.4363675628517254 1.1665497830583207 1.0 13.032240831303497 -6.193094640045131 0.7474167068215419 1.1789019389084154 0.5297943188150948 0.7339220909726962 0.13168472225379518 0.380807831525733 0.44995655877119534 0.07653495737299236 0.14785831404539898 6.410698614972809e-07 6.193094640045131 -0.6491076200933207 AEGEPQEES(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 4 AEGEPQEESPLK 12 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 AEGEPQEES(1)PLK;AEGEPQEES(1)PLK;AEGEPQEES(1)PLK;AEGEPQEES(1)PLK 180.06 8.329700000000001e-05 93746000.0 193262.0 196141.0 186506.0 162589.0 170545.0 222177.0 227134.0 229169.0 211333.0 176058.0 True False 254715.2959006767 259539.74250369304 184032.80857914424 125106.61802500939 146867.77057098443 208284.23706759838 247348.48598313873 193756.19682972913 222503.63093512953 169894.26300788426 1.499257781817248 1.5276545417643008 1.0832196762912698 0.7363792973939537 0.8644657445800201 1.225963922383492 1.4558966359662189 1.1404516750558993 1.3096594728734532 1.0 17.374277610832884 -5.261001120485317 24.704239555109613 1.1025452273165897 1.51345619759816 0.41206327487631167 0.19658945246887463 34.757879663349456 1959079.5758440576 0.05781681941650563 0.13519543755875268 5.482755503610976e-06 5.261001120485317 0.4109109702815703 AEGEPQEES(ph)PLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AEGEPQEESPLK 12 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 AEGEPQEES(1)PLK;AEGEPQEES(1)PLK;AEGEPQEES(1)PLK 153.14 0.00015058 60563000.0 106521.0 182834.0 128903.0 123628.0 123420.0 78349.0 130153.0 79507.0 75184.0 80416.0 True False 124552.90141434957 200984.55121218888 131976.53638734997 116701.52396738395 99236.73697788297 74240.2405144682 117823.96561388084 77420.02549462987 76283.42376584616 94994.78422729447 1.311155158964636 2.1157430152301013 1.3893029755356787 1.2285045428194423 1.0446545858816707 0.781519123585072 1.2403203667683782 0.8149923822068652 0.8030274965762589 1.0 16.535560682719456 -5.8158152584887945 1.7483902180593407 0.9432009063578334 1.7163648768730262 0.6323083434264782 0.22905913465875652 0.21058918639204469 1.3134073264267248 0.0699140832578386 0.1383475491922925 1.5282159971733368e-06 5.8158152584887945 0.7731639705151928 AEGEPQEES(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 4 AEGEPQEESPLK 12 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 AEGEPQEES(1)PLK;AEGEPQEES(1)PLK;AEGEPQEES(1)PLK;AEGEPQEES(1)PLK 174.47 5.9151e-05 113284000.0 144063.0 224350.0 160316.0 177682.0 221477.0 189039.0 210962.0 221524.0 167064.0 187062.0 True False 142008.6352020811 223830.53135902275 147135.43731765583 190749.32700977594 208450.15830053552 180954.24264143204 221884.58011500604 231816.81375312165 148247.49305808847 219395.4174555529 0.6472725677182865 1.020215161988825 0.6706404309810339 0.8694316828582788 0.9501117239277125 0.8247858808541039 1.0113455544711065 1.056616480150891 0.6757091591857053 1.0 17.74317386670849 -5.994384059070689 24.90610266242101 0.9212726333387243 0.7978893045919848 0.16706482236536457 0.1383395665645177 280.29558947848017 1243060.3350541294 0.03721425327155922 0.05500817197013467 1.0130151511495304e-06 5.994384059070689 -0.12338332874673952 AEGEPQEES(ph)PLKSK ddPTM_PC-9_AZD4547_30min_R2 3 AEGEPQEESPLKSK 14 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 AEGEPQEES(0.998)PLKS(0.002)K;AEGEPQEES(0.979)PLKS(0.021)K;AEGEPQEES(0.998)PLKS(0.002)K 160.43 0.00014069999999999998 82427800.0 106394.0 106455.0 99997.0 134818.0 113416.0 120012.0 109361.0 113762.0 102265.0 111185.0 True False 140225.07886732332 140864.4969090126 98670.9744431209 103737.79301733631 97670.14610266373 112507.63066814549 119093.917139671 96182.69689069445 107670.51912186478 107292.44699208037 1.3069426860743871 1.312902267196966 0.9196451121149669 0.9668694854633483 0.9103170711529499 1.048607183658045 1.1099934848951831 0.8964535676755889 1.0035237534456858 1.0 16.711188993489266 -5.2550389122392085 24.890339331454907 0.9820882041832844 1.30992252762078 0.8183896059830816 0.06180433182275224 188.70378579235478 733831.8441696909 0.016523281286354476 0.041526441008945335 5.558544511796299e-06 5.2550389122392085 0.32783432343749563 AEGEPQEES(ph)PLKSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEGEPQEESPLKSK 14 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 AEGEPQEES(0.981)PLKS(0.019)K 68.26100000000001 0.015297 36526000.0 19270.0 18266.0 19414.0 22421.0 24549.0 20306.0 21212.0 19855.0 20455.0 15753.0 True False 22532.030400151318 20079.32776421149 19876.90338800501 21164.82405986275 19738.799676471033 19241.117613330007 19202.645798419075 19333.827288111435 20754.115677941907 18608.894199320614 1.2108204903961426 1.079017783063357 1.0681399536749845 1.13734990554331 1.0607185717242495 1.0339742602240425 1.0319068716678574 1.0389562690306062 1.1152793634938079 1.0 14.183704707888193 -1.5228787452803376 0.837691543444343 1.056067080527716 47.789444667656426 0.5725844067550716 0.03846710847149095 481.76163306157315 1.4150886548106625 0.013559745335926316 42865.949550075165 0.029999999999999995 1.5228787452803376 46.73337758712871 AEGEPQEES(ph)PLKSK ddPTM_PC-9_Lapatinib_30min_R1 4 AEGEPQEESPLKSK 14 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 AEGEPQEES(0.908)PLKS(0.092)K;AEGEPQEES(0.849)PLKS(0.151)K;AEGEPQEES(0.622)PLKS(0.378)K;AEGEPQEES(0.999)PLKS(0.001)K 88.486 0.0026883000000000002 175472500.0 373437.0 290942.0 256271.0 296672.0 289293.0 276087.0 241010.0 238299.0 266681.0 225880.0 True False 368111.71990004147 290268.3416744232 235201.38761466718 318490.2485487797 272277.354511921 264279.40260023135 253488.3185290131 249371.24149327003 236644.5775045736 264923.05703381845 1.38950427351082 1.0956703615169643 0.887810182503831 1.2021990539997551 1.0277601261303722 0.9975704099114902 0.956837511114234 0.9412968591157275 0.8932577637980563 1.0 18.01521388560664 -4.806297752914216 3.229413000767831 0.9939723220936985 1.434570056746641 0.672662606673708 0.08417525825267456 0.18988878826810882 3.131093230038099 0.02218387237188093 0.20577716992413175 1.562076313689171e-05 4.806297752914216 0.4405977346529426 AEGEPQEESPLKS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 AEGEPQEESPLKSK 14 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 AEGEPQEES(0.174)PLKS(0.826)K 107.03 0.00038688 65459000.0 45340.0 40240.0 38208.0 50564.0 42602.0 47847.0 52122.0 47860.0 35718.0 39603.0 True False 59757.176869414085 53246.79306391119 37701.33695533631 38907.25100601253 36687.44766404809 44855.1195262038 56760.75702630665 40464.33671338974 37605.98056025779 38216.51102421506 1.5636481527984134 1.3932928893004521 0.9865195944090154 1.0180743862609487 0.9599894569339908 1.1737104807338987 1.4852417320445979 1.0588181816950897 0.9840244321735592 1.0 15.2219084530552 -5.077055562351204 3.9814134267505783 1.0972165766913273 1.5362724727884787 0.5417992221746305 0.14835208380596293 0.1800891661044364 5.263854337258849 0.04198614921486596 0.1389585482758253 8.374221379622612e-06 5.077055562351204 0.43905589609715134 AEGEPQEESPLKS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEGEPQEESPLKSK 14 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 AEGEPQEES(0.012)PLKS(0.988)K 66.068 0.017683 21721000.0 58280.0 45892.0 46084.0 74037.0 58039.0 40552.0 63836.0 34650.0 45024.0 50252.0 True False 68145.65291753088 50447.854470337945 47182.817334543266 69888.94692119256 46666.67458644759 38425.38173228395 57788.99194738265 33740.47421470969 45682.39082296049 59362.289805386856 1.147961999797167 0.849829995367868 0.7948281221837511 1.1773290274063932 0.7861333304264284 0.6473028897345032 0.9734966783936048 0.5683822899238617 0.769552370245917 1.0 15.857259122235288 -6.480854031504463 24.839865270093526 0.7695287191444242 0.9698730700578057 0.2565147412400426 0.16429354653290218 626.3689097094804 370232.62678483245 0.049404545452634084 0.05601413962815219 3.304805985148133e-07 6.480854031504463 0.20034435091338143 AEGEPQEESPLKS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 AEGEPQEESPLKSK 14 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 AEGEPQEES(0.03)PLKS(0.97)K 66.00399999999999 0.017753 4857600.0 17005.0 12563.0 10924.0 12470.0 12713.0 13801.0 12306.0 11075.0 12117.0 11324.0 True False 16762.505581664936 12533.911145368416 10025.870887859439 13387.085398700543 11965.246334719666 13210.763401702328 12943.144466279557 11589.58493127526 10752.255862333337 13281.338311718468 1.2621096751127066 0.9437235052065064 0.7548840826540315 1.0079620806653777 0.9009066747559936 0.9946861597559133 0.9745361621320561 0.8726217689259124 0.809576234711704 1.0 13.69711290864374 -4.7677159215047356 5.163888524598726 0.9135899219403598 1.2807585417936005 0.6245720782996409 0.08037003400193626 0.10265912960827525 7.643400822565483 0.020039062885771872 0.13506125958074638 1.707198727995976e-05 4.7677159215047356 0.3671686198532407 AEGEWEDQEALDY(ph)FSDKESGK ddPTM_PC-9_Lapatinib_30min_R1 1 AEGEWEDQEALDYFSDKESGK 21 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 AEGEWEDQEALDY(0.732)FS(0.265)DKES(0.002)GK 81.316 0.0035954 60233000.0 51404.0 56197.0 49728.0 53343.0 62977.0 51394.0 51581.0 58209.0 55185.0 54921.0 True False 50670.9695336609 56066.87929923339 45639.555795631146 57266.02216703154 59272.81667754587 49195.99842526548 54251.61179222868 60913.602642401915 48969.48417618762 64414.02167236754 0.7866450225913753 0.8704142024295477 0.7085344869129588 0.889030380035992 0.920185002250416 0.7637467301062757 0.8422329546223885 0.9456574991114514 0.7602301937497974 1.0 15.975087148561723 -14.522878745279654 0.2022106972998114 1.7428602068922379 0.8102903077576422 0.3186272828650457 0.07294108021816738 173.26776337168718 1.712876781241545 52.17741941032687 0.1666270707090494 3.0000000000047255e-15 14.522878745279654 -0.9325698991345956 AEGEWEDQEALDYFS(ph)DKESGK ddPTM_PC-9_AZD4547_30min_R2 5 AEGEWEDQEALDYFSDKESGK 21 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 AEGEWEDQEALDY(0.308)FS(0.637)DKES(0.055)GK;AEGEWEDQEALDY(0.059)FS(0.894)DKES(0.047)GK;AEGEWEDQEALDY(0.041)FS(0.908)DKES(0.051)GK;AEGEWEDQEALDY(0.11)FS(0.876)DKES(0.013)GK;AEGEWEDQEALDY(0.007)FS(0.936)DKES(0.056)GK 89.557 0.00020196 153575000.0 134411.0 129886.0 119803.3 133848.0 137262.5 151217.5 148853.1 135012.2 141549.3 146411.2 True False 177150.90207752152 171869.10944083403 118214.6299639145 102991.41153098576 118205.97119821636 141761.84582008718 162100.73753333584 114149.16676171159 149031.30701937675 141285.38845210077 1.2538515413260873 1.2164676851853078 0.8367081073213185 0.7289601045043832 0.83664682167959 1.0033723046183785 1.1473283919114678 0.8079332761321668 1.0548246259017933 1.0 17.108252746211356 -5.247997971892224 21.815061904863708 0.9204129361897472 1.2351601021157017 0.5080792927802226 0.1211616228896247 120.45961988580561 195496.4926135627 0.03300124079469884 0.08577873677549111 5.64939613012405e-06 5.247997971892224 0.31474716592595453 AEGEWEDQEALDYFS(ph)DKESGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AEGEWEDQEALDYFSDKESGK 21 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 AEGEWEDQEALDY(0.001)FS(0.99)DKES(0.009)GK;AEGEWEDQEALDY(0.001)FS(0.948)DKES(0.05)GK;AEGEWEDQEALDY(0.321)FS(0.673)DKES(0.005)GK 104.38 4.4435e-05 59788200.0 95151.0 97233.6 80877.0 93142.6 103828.0 82098.4 108969.0 95004.7 90498.8 77117.2 True False 111258.1849820862 106886.30921352448 82805.4144077305 87924.1220943836 83483.64873553457 77793.0153780268 98646.66745275946 92510.92729080014 91822.17374309125 91097.9379005808 1.2213030014302537 1.1733120603692944 0.908971336959347 0.9651603990239501 0.916416448708685 0.8539492459524798 1.0828638905132728 1.0155106627304935 1.0079500794332013 1.0 16.475130776998547 -5.180517883709332 5.351024991676939 0.9675833279539038 1.2064028626366479 0.6884165549645715 0.06162554927498206 0.1279983408709383 6.246092936765285 0.016943890355459297 0.04705098154224379 6.599060595891476e-06 5.180517883709332 0.23881953468274408 AEGEWEDQEALDYFS(ph)DKESGK ddPTM_PC-9_Lapatinib_30min_R1 3 AEGEWEDQEALDYFSDKESGK 21 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 AEGEWEDQEALDY(0.004)FS(0.948)DKES(0.048)GK;AEGEWEDQEALDY(0.172)FS(0.82)DKES(0.008)GK;AEGEWEDQEALDY(0.201)FS(0.742)DKES(0.056)GK 103.71 4.8122e-05 85798000.0 97540.0 122648.0 103444.0 115013.0 124397.0 121330.0 124053.0 117198.0 118781.0 111482.0 True False 96149.06171335492 122364.01609147062 94939.2336253873 123471.4396921209 117080.21303391198 116140.99873404398 130475.85734400923 122643.44693233368 105402.6329606187 130751.51515957245 0.73535715128052 0.9358516109135293 0.7261042712164449 0.9443212917374857 0.895440583545241 0.8882573834215426 0.9978917428587593 0.9379887245104314 0.8061293426082495 1.0 16.996468139077564 -5.784955079618884 24.999908612851055 0.9220694228212535 0.812779020943628 0.36376534245860515 0.07517896415925986 261.1155002011039 277594.9801471065 0.02027650999326959 0.03009425713460843 1.6407594730975681e-06 5.784955079618884 -0.10929040187762551 AEGEWEDQEALDYFSDKES(ph)GK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEGEWEDQEALDYFSDKESGK 21 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 AEGEWEDQEALDY(0.027)FS(0.203)DKES(0.769)GK 79.88 0.0021417 4758200.0 13990.0 16813.0 13863.0 18093.0 17965.0 14344.0 18172.0 15672.0 15038.0 15775.0 True False 16358.230684904878 18482.08352675396 14193.546495720275 17079.30786829745 14444.887212831558 13591.775388831162 16450.616606113123 15260.62660585659 15257.90230089907 18634.8826251687 0.8778284797356908 0.991800372372168 0.7616654626281437 0.91652350121217 0.7751531095410262 0.7293727394061392 0.8827861670507409 0.8189279703455303 0.8187817765104353 1.0 14.18571811159607 -5.2577633544999465 24.999339247165913 0.829728416855102 0.9348144235851389 0.18522052724854932 0.0798464137389268 446.68483543924765 3037714.3976589045 0.01933855758848478 0.04714779722883682 5.523783462644762e-06 5.2577633544999465 0.10508600673003687 AEGFVDALHR ddPTM_PC-9_AZD4547_30min_R2 2 AEGFVDALHR 10 0 Q96I24;A0A494C1K6 Q96I24 FUBP3 Far upstream element-binding protein 3 0 ; 134.84 9.2473e-05 6376200.0 55943.0 49975.0 75987.0 102660.0 89057.0 76532.0 64841.0 85411.0 66155.0 68896.0 False True 73731.7103133135 66128.44143561038 74979.36273097622 78993.32308118907 76692.97278571734 71746.44194159351 70611.72338633871 72212.6924995265 69651.81824189074 66483.97201031039 1.1090148209237427 0.9946523866738155 1.1277810344927701 1.188155892204195 1.1535558190449833 1.0791539640632033 1.0620864134800518 1.0861669409331876 1.0476482697376908 1.0 16.020718956429 -8.343892491161347 0.842852626252087 1.0020028251153938 1.108112742511058 0.3263165573593455 0.048621258026292205 0.81062787332192 1.26724181021911 0.05177045578282954 0.01915229614004118 4.5300970778457244e-09 8.343892491161347 0.10610991739566411 AEGFVDALHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AEGFVDALHR 10 0 Q96I24;A0A494C1K6 Q96I24 FUBP3 Far upstream element-binding protein 3 0 ; 117.67 0.00064828 0.0 45986.0 44509.0 57614.0 58931.0 62062.0 52709.0 56598.0 50592.0 47298.0 41764.0 False True 53770.52153509906 48927.55937026656 58987.736262311766 55629.2871268798 49901.39661579475 49944.84725110858 51236.627705964725 49264.01360665492 47989.64377097514 49335.48259635793 1.0898955215463635 0.9917316461778873 1.1956452670165305 1.1275715610611357 1.011470730388246 1.0123514481399973 1.0385350463714151 0.9985513673741121 0.9727206717243678 1.0 15.590338000858374 -6.274742722241343 23.038451854864267 1.0075162622813012 1.1001363462250078 0.47641751615169703 0.04907125216161002 266.2134205850626 461021.65081363515 0.01598367688720524 0.018251166690858533 5.31199035436438e-07 6.274742722241343 0.09262008394370658 AEGFVDALHR ddPTM_PC-9_Lapatinib_30min_R1 2 AEGFVDALHR 10 0 Q96I24;A0A494C1K6 Q96I24 FUBP3 Far upstream element-binding protein 3 0 ; 139.15 0.00010119 5814500.0 100949.0 93895.0 100309.0 97070.0 98876.0 99725.0 88883.0 86206.0 98729.0 80725.0 False True 99509.44874822051 93677.59189639165 92061.98122393758 104208.8516160274 93060.3080776954 95459.99422032929 93484.92683214089 90211.44547047556 87609.10035753963 94678.20869069868 1.0510280044831104 0.9894313928395507 0.9723671634377032 1.1006635323706226 0.9829115840342021 1.00825729109625 0.9873964466051941 0.9528216335945323 0.9253354237377589 1.0 16.530744790126697 -7.4041515906821616 1.7007080699459873 0.9542663187718292 1.0185623714666605 0.31118125875266966 0.03878916929404869 0.4543596530659779 2.555696059969026 0.023096100121499576 0.012549216110685869 3.94319640605259e-08 7.4041515906821616 0.0642960526948313 AEGLEEADTGASGCHSHPEEQPTSIS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 1 AEGLEEADTGASGCHSHPEEQPTSISPSR 29 0 Q9BV36;Q9BV36-4;Q9BV36-2;Q9BV36-3 Q9BV36;Q9BV36-2 MLPH Melanophilin 1 AEGLEEADTGASGCHS(0.001)HPEEQPT(0.008)S(0.003)IS(0.923)PS(0.066)R 82.294 6.199899999999999e-07 8781100.0 6621.5 3434.1 19097.0 20989.0 21433.0 15625.0 9072.2 23750.0 14155.0 19655.0 True False 8726.999264244052 4544.105667514348 18843.761302241855 16150.310326817445 18457.397910509906 14647.966279953476 9879.608224819838 20079.98322070637 14903.204401994757 18966.8844325164 0.4601177012120494 0.2395810278531584 0.9935085210903978 0.8515004340475507 0.9731381016308065 0.7722916397825113 0.5208872474533804 1.0586864327744676 0.7857486797591827 1.0 14.211195095573222 -5.259762979177591 24.999953693903883 0.8587066839045767 0.3498493334707096 0.6399804194255785 0.1557255284430825 88.20331792476809 1315337.8735430152 0.040077274409286226 0.09525605195552236 5.498408734780265e-06 5.259762979177591 -0.5088573504338672 AEGLEEADTGASGCHSHPEEQPTSIS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 1 AEGLEEADTGASGCHSHPEEQPTSISPSR 29 0 Q9BV36;Q9BV36-4;Q9BV36-2;Q9BV36-3 Q9BV36;Q9BV36-2 MLPH Melanophilin 1 AEGLEEADT(0.001)GASGCHSHPEEQPT(0.021)S(0.015)IS(0.811)PS(0.152)R 103.39 2.2353e-11 8966700.0 9833.2 7366.8 20089.0 12833.0 15630.0 20295.0 14647.0 13099.0 19166.0 13681.0 True False 9692.976764811965 7349.742627214839 18437.35996578254 13776.781629633044 14710.67412976232 19427.030159955706 15405.349991678591 13707.627360250535 17007.323253072616 16045.742621213389 0.6040840236336146 0.45804939046560916 1.1490499630355093 0.8585942050085829 0.9167960920870043 1.2107280179274509 0.9600895611594715 0.8542843845773936 1.0599274620414243 1.0 13.969902940820711 -5.255206614465605 24.998540639778998 0.9938893348771696 0.5310666631954966 0.7293918320347661 0.11447070849209147 246.61182757327472 989110.3916424769 0.02925017379552206 0.0734064923801909 5.556398501722321e-06 5.255206614465605 -0.462822671681673 AEGNDHIER ddPTM_PC-9_AZD4547_30min_R2 1 AEGNDHIER 9 0 A0A087WTD5;A0A0G2JP90;A0A087WW46;J3KN36;A0A0G2JN29;A0A087X117;Q5JPE7-3;Q5JPE7-2;Q15155;P69849;Q5JPE7 A0A087WTD5 NOMO2;NOMO1;NOMO3 Nodal modulator 2;Nodal modulator 1;Nodal modulator 3 0 139.15 0.00071139 2659300.0 25106.0 25057.0 33162.0 37749.0 26121.0 28527.0 30871.0 28060.0 22674.0 28890.0 False True 33089.18576275939 33156.18523365861 32722.250212334122 29046.551266236194 22494.55003128024 26743.202180366905 33618.45919494866 23723.971754653507 23872.50135011158 27878.56989343163 1.186903987157369 1.1893072478395106 1.1737420655872197 1.0418953116056267 0.8068760383788588 0.9592745353364691 1.2058889434952464 0.8509752058782264 0.8563029395469849 1.0 14.766868935713743 -5.885659019832775 3.6436702580933416 0.9506853552836102 1.184976406670958 0.5071891085825666 0.10402037211494138 0.2042164281150075 5.191579783460053 0.03197967213135349 0.049907985046131434 1.3011907886222227e-06 5.885659019832775 0.23429105138734785 AEGNDHIER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AEGNDHIER 9 0 A0A087WTD5;A0A0G2JP90;A0A087WW46;J3KN36;A0A0G2JN29;A0A087X117;Q5JPE7-3;Q5JPE7-2;Q15155;P69849;Q5JPE7 A0A087WTD5 NOMO2;NOMO1;NOMO3 Nodal modulator 2;Nodal modulator 1;Nodal modulator 3 0 ; 136.96 0.00081591 5081300.0 47980.0 46031.0 52937.0 61675.0 56475.0 51876.0 51156.0 45043.0 49364.0 38253.0 False True 56102.06635180384 50600.653471718986 54199.21884469045 58219.549703047844 45409.129159179654 49155.53123752129 46310.13334263277 43860.66897700345 50085.855112487116 45187.96608941864 1.241526698519429 1.1197816111393384 1.1994170912105273 1.2883861510350367 1.0048942913102876 1.0878013659710104 1.024833320689707 0.9706271995117304 1.1083892338366472 1.0 15.46365100230864 -6.272991933647409 24.99819910951102 1.0336448998233674 1.2047523838521004 0.7191040110508329 0.05488401789725005 413.7236382185747 895241.2649844242 0.01691386165979124 0.019339914431104745 5.333448014556853e-07 6.272991933647409 0.171107484028733 AEGNDHIER ddPTM_PC-9_Lapatinib_30min_R1 2 AEGNDHIER 9 0 A0A087WTD5;A0A0G2JP90;A0A087WW46;J3KN36;A0A0G2JN29;A0A087X117;Q5JPE7-3;Q5JPE7-2;Q15155;P69849;Q5JPE7 A0A087WTD5 NOMO2;NOMO1;NOMO3 Nodal modulator 2;Nodal modulator 1;Nodal modulator 3 0 ; 150.15 0.00019380000000000002 5238900.0 66219.0 68194.0 58645.0 56896.0 59432.0 61022.0 49409.0 50813.0 64974.0 43194.0 False True 65274.704916922616 68036.10098282696 53823.43447624649 61080.32163949204 55936.32660780769 58412.23130922968 51967.156259906274 53173.95748197647 57655.94391344774 50660.025347612835 1.2884854373646388 1.3429938203935958 1.0624438915481655 1.2056907042659073 1.1041511768695451 1.1530241232297793 1.0258020185210002 1.0496235861927394 1.1380954414813487 1.0 15.628560178448781 -1.522878745284983 0.2908383087313842 1.0381372619074007 3.4344040039413892 0.6224722244803584 0.06610908278972784 33.22953115597176 0.4717463800949735 0.06756385778273291 40.98987190631921 0.029999999999679103 1.522878745284983 2.3962667420339887 AEGSDVANAVLDGADCIMLSGETAK ddPTM_PC-9_Lapatinib_30min_R1 3 AEGSDVANAVLDGADCIMLSGETAK 25 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ;; 165.65 1.9780000000000003e-10 7313000.0 52020.9 56421.1 59540.9 54022.3 61594.6 50106.3 60786.6 49457.6 47484.2 56426.2 False True 51279.0724265353 56290.460409452055 54645.67703652055 57995.28015510987 57971.72672764283 47963.37035249022 63933.832716881945 51755.58064984552 42136.02936520664 66179.39348681459 0.7748495373677308 0.8505738333891987 0.8257204268184781 0.8763344161905126 0.8759785134506101 0.7247478078209696 0.9660685803900568 0.7820497880530919 0.6366940998575593 1.0 16.01409444941727 -10.09005896566538 9.926348384180752 1.0000025114902733 0.8188389522360284 0.29528043175881025 0.0863829152929537 0.0 0.0 0.0825622725543659 0.02002429237839322 8.127201628425136e-11 10.09005896566538 -0.18116355925424488 AEGSST(ph)ASSGSQLAEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEGSSTASSGSQLAEGK 17 0 Q9NZB2-4;Q9NZB2;Q9NZB2-6;Q9NZB2-2;Q9NZB2-5;A0A0C4DH52 Q9NZB2-4 FAM120A Constitutive coactivator of PPAR-gamma-like protein 1 1 AEGS(0.001)S(0.027)T(0.786)AS(0.016)S(0.063)GS(0.106)QLAEGK 131.82 6.1828e-05 4913900.0 17233.0 16419.0 13823.0 16542.0 18766.0 18233.0 18129.0 15723.0 15638.0 14345.0 True False 20150.20653273522 18048.969810609233 14152.592744019426 15615.205369887599 15088.937012858169 17276.829382637923 16411.68987740616 15310.287909895553 15866.676165810577 16945.634945042486 1.1891089710173561 1.0651102699394295 0.8351763029192261 0.9214883608982672 0.890432082468087 1.0195445280551336 0.9684907016250498 0.9034944963437112 0.9363282176955214 1.0 14.048626074494825 -5.002331425706063 4.1815817665506705 0.9332129869553013 1.1733039499111482 0.715520252978947 0.05136547546221829 0.10149286305347407 4.262044347315972 0.013457755734927496 0.05269210175169785 9.946460775288182e-06 5.002331425706063 0.24009096295584686 AEGSSTASS(ph)GSQLAEGK ddPTM_PC-9_Lapatinib_30min_R1 2 AEGSSTASSGSQLAEGK 17 0 Q9NZB2-4;Q9NZB2;Q9NZB2-6;Q9NZB2-2;Q9NZB2-5;A0A0C4DH52 Q9NZB2-4 FAM120A Constitutive coactivator of PPAR-gamma-like protein 1 1 AEGSSTAS(0.281)S(0.438)GS(0.281)QLAEGK;AEGSSTAS(0.321)S(0.626)GS(0.053)QLAEGK 247.44 2.1008e-47 6722000.0 53335.0 51345.0 57391.0 41212.0 57322.0 50650.0 46870.0 40967.0 57745.0 39552.0 True False 52574.43311955887 51226.1138071274 52672.53351566654 44242.86795920183 53950.432659388054 48483.817570916784 49296.69926332868 42870.47637738634 51241.15001819252 46388.510500272765 1.1333503178389341 1.1042845147361693 1.1354650741665184 0.9537462505708538 1.1630128253217102 1.045168664569036 1.0626920056646099 0.92416152006291 1.1046086512713362 1.0 15.501479902642368 -1.5228787588446624 0.18836583271945073 0.9936970157333729 1.6369195078350676 0.2250416403786688 0.06769687001041108 79.27598097734378 0.9212719150756631 0.1358551851132642 14.783726071475945 0.02999999906300965 1.5228787588446624 0.6432224921016947 AEGVS(ph)TPLAGR ddPTM_PC-9_AZD4547_30min_R2 1 AEGVSTPLAGR 11 0 P29590;P29590-11 P29590 PML Protein PML 1 AEGVS(0.5)T(0.5)PLAGR 77.744 0.019162000000000002 3691300.0 31765.0 26350.0 42206.0 55184.0 42463.0 34967.0 31160.0 54624.0 32550.0 35783.0 True False 41865.60924695498 34867.122197665485 41646.32086308949 42462.181384300995 36567.74541473346 32780.50796231253 33933.17963508144 46183.1159346469 34270.52654785796 34530.24806149755 1.2124329130909608 1.0097559141645311 1.206082295989255 1.2297097115745261 1.0590061603266554 0.9493273232190867 0.9827088289272424 1.337468408926454 0.9924784347573458 1.0 15.075573077940195 -6.298302308440755 22.690823909726696 1.0616235309108806 1.1564129156903356 0.1753149692668543 0.11661891350445885 420.42625986845496 258789.91551350107 0.03747971348873392 0.04250048542560723 5.031502485468028e-07 6.298302308440755 0.09478938477945498 AEGVS(ph)TPLAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEGVSTPLAGR 11 0 P29590;P29590-11 P29590 PML Protein PML 1 AEGVS(0.5)T(0.5)PLAGR 70.41199999999999 0.032288 2508200.0 27403.0 25957.0 38798.0 32040.0 41594.0 31491.0 37587.0 30469.0 29366.0 32284.0 True False 32041.786666079228 28533.83941616322 39723.09146223437 30244.90267508152 33443.95428502733 29839.55652326283 34026.48725368556 29669.22103457405 29795.422194986153 38136.833639996636 0.8401795222054007 0.7481963417706992 1.0415938522115302 0.7930627634319825 0.8769462772062028 0.7824340322781307 0.8922210893250383 0.7779676025189979 0.7812767697562 1.0 15.218897446548175 AEGVS(ph)TPLAGR ddPTM_PC-9_Lapatinib_30min_R1 1 AEGVSTPLAGR 11 0 P29590;P29590-11 P29590 PML Protein PML 1 AEGVS(0.5)T(0.5)PLAGR 83.081 0.01323 3784800.0 44077.0 39197.0 54811.0 31614.0 50544.0 48045.0 40016.0 43829.0 52549.0 32712.0 True False 43448.45389726815 39106.241754756484 50304.651156578526 33938.99902121244 47571.10129332735 45990.227348365224 42087.83268020827 45865.45534563097 46630.37825449819 38366.225613999886 1.1324662043746558 1.0192882184503071 1.3111701855348077 0.8846061471532413 1.2399213248636216 1.1987164911938413 1.097002168095742 1.1954643599055157 1.2154017630934928 1.0 15.22754922226436 AEGYEVAHGGR ddPTM_PC-9_AZD4547_30min_R2 2 AEGYEVAHGGR 11 0 A8MU39;H0YDU8;P53041 A8MU39 PPP5C Serine/threonine-protein phosphatase;Serine/threonine-protein phosphatase 5 0 ; 115.0 0.0011768 7257400.0 57523.0 50940.0 78450.0 100473.0 93985.0 78034.0 77330.0 103859.0 73753.0 79214.0 False True 75814.11744727177 67405.35881400688 77409.70174168055 77310.50214237599 80936.8050491893 73154.52164415305 84212.22019194014 87809.97799239313 77651.4330102664 76440.74197086527 0.9918024798368344 0.8817988558993559 1.012675959780513 1.0113782277498329 1.0588176273856376 0.9570095705250383 1.1016667031311247 1.1487326748589273 1.0158382952361003 1.0 16.22205416142961 -5.8225658759842815 0.8337532910288104 1.063058738301004 0.9300919034262001 0.30938751000617304 0.058240380466850414 0.8944386776671793 1.1531811354183854 0.02709197743973392 0.08351808242447487 1.5046452692848938e-06 5.8225658759842815 -0.13296683487480387 AEGYEVAHGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AEGYEVAHGGR 11 0 A8MU39;H0YDU8;P53041 A8MU39 PPP5C Serine/threonine-protein phosphatase;Serine/threonine-protein phosphatase 5 0 ; 87.001 0.011676 1925000.0 52401.0 51370.0 61397.0 63838.0 77542.0 60072.0 67702.0 58706.0 60886.0 46557.0 False True 61271.45433307369 56469.67410749719 62860.93732941917 60261.36382558846 62348.20173990455 56921.71856928787 61288.77643996641 57165.029704148576 61776.3425650047 54997.41555499075 1.1140787928809066 1.0267695952191491 1.142979841781217 1.0957126479031436 1.1336569384349324 1.0349889716612783 1.114393755079001 1.0394130183624806 1.123259010293599 1.0 15.747076204484864 -7.76106831727366 24.999585931465166 1.0610020141960896 1.0931480613203406 0.13576959064437466 0.04568596623148616 24.950906912392416 1681461.962201816 0.021879153875640243 0.011614303735593157 1.733531280850654e-08 7.76106831727366 0.032146047124250954 AEGYEVAHGGR ddPTM_PC-9_Lapatinib_30min_R1 2 AEGYEVAHGGR 11 0 A8MU39;H0YDU8;P53041 A8MU39 PPP5C Serine/threonine-protein phosphatase;Serine/threonine-protein phosphatase 5 0 ; 87.713 0.008579799999999999 7262700.0 60803.0 56347.0 69251.0 58242.0 62914.0 62006.0 60275.0 56135.0 70824.0 50241.0 False True 59935.93807009541 56216.53198344933 63557.4500965904 62525.31096961646 59213.52221368305 59354.14792304573 63395.744572159914 58743.2370308927 62847.055310216754 58925.089908075526 1.017154800503433 0.9540338770996937 1.07861439321928 1.061098270145321 1.0048948980147079 1.0072814146849762 1.0758701373397768 0.9969138294491103 1.066558496699107 1.0 15.846594434294909 -5.254059253075849 24.993589448762503 1.0364197454540776 0.9855943425171179 0.26298070387858175 0.03402381070767114 746.7074565961516 2528786.0904690307 0.00841807660363486 0.02133342704165337 5.571097343410964e-06 5.254059253075849 -0.050825402936959696 AEHMETNAVGPS(ph)PSSDTR ddPTM_PC-9_Lapatinib_30min_R1 1 AEHMETNAVGPSPSSDTR 18 0 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 AEHMETNAVGPS(0.516)PS(0.211)S(0.211)DT(0.062)R 79.935 0.011084 0.0 5014.3 5927.0 6958.6 6419.7 5335.0 6473.9 4185.4 5024.4 7051.0 3747.0 True False 4942.795162489997 5913.2763956537965 6386.490768972788 6891.82615349141 5021.205789013559 6197.026388397988 4402.09953268052 5257.851966473984 6256.842129678335 4394.663957436338 1.1247265343522228 1.3455582617751172 1.4532375696590003 1.568225971369108 1.142568769226833 1.4101251992002302 1.001691955361365 1.1964172954742127 1.4237361924091947 1.0 12.101537137067107 -7.236505632852172 24.79561300151909 1.1718294195842236 1.3474053445003191 0.22574847852540403 0.16672642349715222 1153.9660250376105 1147574.507045121 0.06452093159343232 0.0499561317774268 5.8008864865369136e-08 7.236505632852172 0.17557592491609553 AEHS(ph)RQDLR ddPTM_PC-9_Lapatinib_30min_R1 1 AEHSRQDLR 9 1 A0A096LNN2 A0A096LNN2 CYP26A1 1 AEHS(1)RQDLR 98.523 0.021404 5549400.0 2191.7 5298.4 4544.1 3385.0 4177.3 4160.4 5005.2 4333.1 5431.1 3521.5 True False 2160.4459560914456 5286.131880332726 4170.501638733259 3633.9441920289746 3931.5994268877885 3982.469390366087 5264.34476536831 4534.431644759259 4819.392325981567 4130.186582896202 0.5230867692607922 1.2798772583842792 1.0097610737500355 0.8798498854937328 0.9519181150723804 0.9642347410788082 1.2746021661996696 1.097875738480461 1.166870365116066 1.0 12.011991242127332 -7.1490408204232505 8.138173254084029 1.1426578632278968 0.9511213789215194 0.21706612551935567 0.18444924818900668 0.48241893010826725 31.621471451769708 0.06776490455331198 0.0524643848725322 7.095110761107216e-08 7.1490408204232505 -0.19153648430637737 AEIAFEDRK ddPTM_PC-9_Lapatinib_30min_R1 1 AEIAFEDRK 9 1 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 0 68.37100000000001 0.027361 3048500.0 23565.0 22729.0 23602.0 19086.0 24921.0 20902.0 16499.0 17528.0 23772.0 19673.0 False True 23228.958778708267 22676.372396965602 21661.534666354684 20489.64810902956 23455.195776571116 20008.07018494181 17353.237489772986 18342.414869109944 21094.547029742356 23073.451837375243 1.0067396479048327 0.9827906356097774 0.9388077180227762 0.8880183274459029 1.0165447260291376 0.8671468112340256 0.7520867537324242 0.7949575554793328 0.9142345574654165 1.0 14.49394622995696 -6.8964000967912 6.53297353395037 0.8430267764098158 0.9611067774662444 0.30973682102614375 0.07198547019198451 0.229466436873195 12.674150481737426 0.025225608175794383 0.02224099461129206 1.2694041190497088e-07 6.8964000967912 0.11808000105642857 AEIDMLDIR ddPTM_PC-9_Lapatinib_30min_R1 1 AEIDMLDIR 9 0 P09525-2;P09525;Q6P452 P09525-2 ANXA4 Annexin A4;Annexin 0 92.06200000000001 0.021705000000000002 0.0 10810.0 8177.1 10992.0 12933.0 14927.0 12651.0 10772.0 13192.0 13691.0 12198.0 False True 10655.847417688794 8158.166427349528 10088.28019034703 13884.13596322326 14049.023207611135 12109.946220921396 11329.721452199208 13804.948479763727 12148.975407378544 14306.408047186662 0.7448303852750973 0.5702456130456744 0.705158147109531 0.970483710336611 0.9820091221551491 0.846470069983975 0.7919333360848172 0.9649486044457157 0.8491981612231189 1.0 13.804373875303881 -5.6592565027145465 5.316823509472626 0.9078559388442035 0.6539370079805614 0.6807429112367414 0.07597157835734096 0.11634116266888805 5.047225816503903 0.020923391755386052 0.03673681862359499 2.1915102047597605e-06 5.6592565027145465 -0.25391893086364203 AEIIADK ddPTM_PC-9_Lapatinib_30min_R1 1 AEIIADK 7 0 Q13151 Q13151 HNRNPA0 Heterogeneous nuclear ribonucleoprotein A0 0 139.68 0.012925 3622400.0 47924.0 41195.0 38686.0 34066.0 36447.0 39352.0 32680.0 32402.0 40164.0 35061.0 False True 47240.594971814724 41099.61550851324 35505.386412278516 36571.32728084464 34303.25911755902 37669.00669399246 34372.01049553195 33907.515209316574 35640.30737433 41121.24713415413 1.1488123114967017 0.9994739550196442 0.8634316536277606 0.8893535539312363 0.8341979270630563 0.9160472825909421 0.8358698456638864 0.8245740966633758 0.8667127059171359 1.0 15.32759639911469 -4.898413310095805 1.9990548561878307 0.8699587738524085 1.194449466416256 0.7440482913520003 0.04945712064046882 0.2526002983694813 1.3517824321607725 0.012581386288188088 0.13982748029060685 1.26353329363066e-05 4.898413310095805 0.32449069256384744 AEIS(ph)FEDR ddPTM_PC-9_AZD4547_30min_R2 1 AEISFEDR 8 0 Q60FE5;P21333-2;P21333;H0Y5C6 Q60FE5 FLNA Filamin-A 1 AEIS(1)FEDR 81.525 0.041266000000000004 0.0 6190.6 9310.2 8634.1 13037.0 8680.4 11779.0 8720.0 11476.0 9550.8 9242.9 True False 8159.082027520836 12319.540079115945 8519.606192579275 10031.521069642145 7475.276294610656 11042.457267940605 9496.063107121641 9702.647892245308 10055.63578965536 8919.308884319806 0.9147661700408815 1.3812213747607467 0.9551868090987172 1.1246971261728154 0.8381003944994251 1.2380395623873175 1.0646635552465027 1.0878250790599502 1.1274007795977583 1.0 13.122716211422844 -11.428245747310793 2.640181566925681 0.9522650482103304 1.0848657781500193 0.025656365164715145 0.1489111024200642 81430788.02030773 40875123.76936183 24049821.87705652 0.0358606781030716 3.730390124100425e-12 11.428245747310793 0.13260072993968886 AEIS(ph)FEDR ddPTM_PC-9_Lapatinib_30min_R1 1 AEISFEDR 8 0 Q60FE5;P21333-2;P21333;H0Y5C6 Q60FE5 FLNA Filamin-A 1 AEIS(1)FEDR 93.649 0.0070664000000000005 888560.0 7072.1 10116.0 9891.6 6949.2 8490.8 9927.1 8538.9 7983.2 8899.8 8123.3 True False 6971.250557135699 10092.57702352519 9078.3508306802 7460.267349851628 7991.387837555079 9502.54107420036 8981.002460841415 8354.128616104437 7897.410804951251 9527.401581383137 0.7317053340921156 1.0593210475400159 0.9528674479744406 0.7830327383732035 0.8387793638478008 0.9973906309112281 0.9426497229203181 0.8768527855935752 0.8289154957405235 1.0 13.217867084652157 -6.724633957834319 24.99955977075966 0.9223084350925054 0.8829077796439538 0.07076626940590114 0.09678640893918716 743.0635844142793 504713.07694110734 0.03296038958866134 0.03295951211921652 1.8852373796260755e-07 6.724633957834319 -0.039400655448551536 AEISFEDR ddPTM_PC-9_AZD4547_30min_R2 2 AEISFEDR 8 0 Q60FE5;P21333-2;P21333;H0Y5C6 Q60FE5 FLNA Filamin-A 0 ; 125.81 0.015985 8361400.0 66772.0 76435.0 79626.0 81449.0 73695.0 91435.0 83242.0 101429.0 78871.0 72472.0 False True 88004.10705612067 101141.11898210863 78570.10721329578 62672.191424505865 63463.72131829552 85717.55499568279 90650.37673887835 85755.4786565486 83039.96004166221 69934.77733876008 1.258374022266973 1.4462206477356296 1.1234769052413889 0.8961520120515339 0.9074701276430877 1.2256785287307321 1.2962131315550358 1.2262208005775717 1.1873914982158502 1.0 16.093722440543523 -1.5330766439756836 0.015198983900315497 0.09215940234893627 2.4472280982950827 0.07835057689484248 0.16059033187369354 21401.886961578097 25.246579420971855 1560.383931869397 2442.7159770292833 0.029303760489712817 1.5330766439756836 2.355068695946146 AEISFEDR ddPTM_PC-9_Lapatinib_30min_R1 2 AEISFEDR 8 0 Q60FE5;P21333-2;P21333;H0Y5C6 Q60FE5 FLNA Filamin-A 0 ; 113.41 0.017113999999999997 9077600.0 56827.0 69430.0 82418.0 66699.0 91132.0 91991.0 95710.0 86106.0 77697.0 84374.0 False True 56016.636559204504 69269.2391007666 75641.91018268022 71604.26696134136 85771.79493240555 88056.75937149476 100665.3954873734 90106.7991054073 68945.94567431828 98957.93347871192 0.5660651409141941 0.6999867182520336 0.7643844967614699 0.7235828846076808 0.866750061538593 0.8898403218013617 1.017254422648476 0.9105565965036175 0.6967197398998849 1.0 16.594527752629055 -5.136042757057716 0.590483734515598 0.9107015143951547 0.45823338858118196 0.6017339412697469 0.08758785959365287 1.9261073521044958 0.6803927701215894 0.05029134693934752 0.5618376938855818 7.31067105094384e-06 5.136042757057716 -0.4524681258139727 AEISFEDRK ddPTM_PC-9_Lapatinib_30min_R1 1 AEISFEDRK 9 1 Q60FE5;P21333-2;P21333;H0Y5C6 Q60FE5 FLNA Filamin-A 0 96.03399999999999 0.0033124 4095200.0 21642.0 24845.0 32357.0 25013.0 26903.0 22476.0 24972.0 21584.0 29194.0 21394.0 False True 21333.38111134327 24787.47292897224 29696.732361632003 26852.539460921937 25320.618433333064 21514.753874115035 26264.927971065586 22586.87143626594 25905.864293551185 25091.924394286896 0.8502090463894671 0.9878665557678799 1.1835175291853486 1.0701666017707239 1.0091142486902376 0.8574373784983054 1.0467482508852834 0.9001649726558508 1.0324383210500034 1.0 14.614935500261808 -6.534691530371145 24.830437687804956 0.9624350913952873 1.0328715266713588 0.07002766485699907 0.0937008754463962 500.0640390412248 1051124.7795990545 0.031826157454832145 0.03184902099322258 2.9194999330553383e-07 6.534691530371145 0.07043643527607157 AEISS(ph)IR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AEISSIR 7 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 AEIS(0.084)S(0.916)IR;AEIS(0.084)S(0.916)IR 87.696 0.017768 12911900.0 93890.0 135870.0 126761.0 104689.0 139692.0 107362.0 143691.0 91460.0 93215.0 97038.0 True False 109783.72258797113 149358.2756664524 129783.46298376979 98823.61473631718 112320.35538741277 101731.74772000068 130079.5482472485 89059.27190988023 94578.09302954568 114630.22124761448 0.9577205853142833 1.302957231006484 1.1321923797339846 0.8621078600454481 0.9798494163662815 0.8874775483530507 1.1347753396223645 0.7769266336623564 0.8250711897802772 1.0 16.806627922512206 -5.728511643721106 9.939301485843844 0.9240986692861559 1.1486367673900344 0.37233097736392706 0.12265063296457947 0.3878918891811819 112.13796144327927 0.03278812948730381 0.05637014251127229 1.8684795814160612e-06 5.728511643721106 0.22453809810387848 AEISS(ph)IR ddPTM_PC-9_Lapatinib_30min_R1 1 AEISSIR 7 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 AEIS(0.093)S(0.907)IR 79.71300000000001 0.026466000000000003 7986700.0 35471.0 34046.0 37302.0 39735.0 50700.0 54909.0 52688.0 54863.0 55792.0 46458.0 True False 34965.177035415276 33967.168578780016 34235.17354988399 42657.24445207428 47717.925680035136 52560.67006913069 55415.92683563606 57412.13526722838 49508.11744419424 54488.203398606165 0.6417017786332391 0.6233857323262179 0.6283043193668548 0.7828711866312971 0.8757478262029793 0.9646247589524161 1.0170261337163784 1.0536617411888647 0.9086024929473209 1.0 15.733656302274275 -6.204302276388015 1.301905932762709 0.999053640064331 0.6188842680055141 0.9426077724300188 0.03844338303888463 0.09155151357788875 0.31482865064971416 0.01484953471504982 0.022348795051650185 6.247377132820746e-07 6.204302276388015 -0.38016937205881685 AEISS(ph)IRENK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEISSIRENK 10 1 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 AEIS(0.024)S(0.976)IRENK 98.105 0.023591 4129700.0 16740.0 18375.0 19648.0 17258.0 25038.0 20588.0 23011.0 14922.0 19813.0 22043.0 True False 19573.751369929076 20199.14856385559 20116.48283545493 16291.090211190918 20131.983636786892 19508.329036897358 20831.23149478697 14530.313311165894 20102.727642486567 26039.221407708003 0.7517026359372999 0.7757201433786471 0.7725454813138211 0.6256366101011188 0.7731407679811625 0.7491901824346636 0.7999944072298802 0.5580164277440608 0.7720172323023398 1.0 14.668398691031811 -11.219646442464224 3.422656057764701 1.0248300796724132 0.7290628142657961 0.5479036570452248 0.07332012419514837 108773233.94324484 72319085.63176931 22408678.246935382 0.018058138829560512 6.0305032733899855e-12 11.219646442464224 -0.29576726540661713 AEISS(ph)IRENK ddPTM_PC-9_Lapatinib_30min_R1 1 AEISSIRENK 10 1 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 AEIS(0.076)S(0.924)IRENK 100.09 0.019902 5339000.0 25342.0 24352.0 34267.0 28913.0 31554.0 37529.0 36240.0 37343.0 37435.0 30644.0 True False 24980.618432846368 24295.614440182424 31449.699534445208 31039.358470940573 29698.05575755088 35923.972154371906 38116.32987631817 39078.092107323886 33218.67609197398 35940.77456943665 0.6950495289016227 0.6759902848850383 0.8750423414967086 0.8636251956944704 0.826305390279639 0.999532497135467 1.0605316755953158 1.0872913167696487 0.9242615522321689 1.0 15.133333880646708 -5.726709345711202 0.6005037833485136 1.032827917294948 0.6164714965279219 0.7773666854622663 0.06346207610305785 0.6794877619799513 0.38787848551970977 0.04124059156844474 0.17155240309145778 1.8762497798304059e-06 5.726709345711202 -0.41635642076702606 AEITFDDHK ddPTM_PC-9_AZD4547_30min_R2 3 AEITFDDHK 9 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7 O75369-2 FLNB Filamin-B 0 ;; 140.17 0.00066297 17950200.0 83148.0 82525.0 95757.0 97710.0 100625.0 107474.0 87581.0 113235.0 97834.0 102843.0 False True 109587.33441416084 109199.59238566762 94487.19961348778 75184.46910445137 86654.95566393202 100753.63379019014 95375.5393331214 95737.13263143951 103005.30550793042 99242.49787297312 1.1042379702537188 1.1003309542393747 0.952084053088104 0.7575834014243055 0.8731637909280285 1.0152267017618926 0.9610352558356472 0.9646787886574524 1.037915285443274 1.0 16.598670426988576 -5.273212155306811 5.744979687832476 0.937264247413857 1.1037212624302208 0.4030053251821316 0.07611828037492199 0.15463565424510048 20.39982100164106 0.021812662754324627 0.050815661430650125 5.330744220060696e-06 5.273212155306811 0.16645701501636379 AEITFDDHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AEITFDDHK 9 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7 O75369-2 FLNB Filamin-B 0 ;; 133.23 0.00098715 12273000.0 94822.0 113363.0 105507.0 114690.0 130284.0 101711.0 126676.0 99070.0 89294.0 81034.0 False True 110873.49178013208 124616.92945003338 108022.68701752563 108264.29112999672 104755.78545151949 96377.09610801772 114676.33222518081 96469.51747334168 90599.7558223488 95724.82273520913 1.1582522548704708 1.301824603997906 1.1284710060663623 1.1309949502802827 1.0943429557586282 1.0068140462857047 1.1979790502448329 1.0077795363506965 0.946460418871319 1.0 16.54660546302111 -5.92756479030839 0.35097884853864464 0.9806239363617884 1.3055933991962783 0.5400182382516527 0.06989906458199564 2.3381243558683416 0.41521022874895647 0.07555611376364899 0.30194770434282736 1.1815040364822833e-06 5.92756479030839 0.3249694628344899 AEITFDDHK ddPTM_PC-9_Lapatinib_30min_R1 3 AEITFDDHK 9 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7 O75369-2 FLNB Filamin-B 0 ;; 129.85 0.0010782 20964400.0 146338.0 153248.0 152506.0 147181.0 175125.0 140006.0 146186.0 127629.0 141285.0 143214.0 False True 144251.19328489774 152893.16367152878 139967.54537018423 158005.18172142297 164824.49180899706 134018.26974992643 153754.7957864087 133559.10927257137 125371.99550299303 167968.34907934043 0.8587998517313532 0.9102498447449118 0.8332971428091496 0.9406842574060704 0.9812830376224132 0.7978781150407237 0.915379573765901 0.7951445019530688 0.7464024989837409 1.0 17.357829880487294 -6.783132050598932 24.999741099865492 0.8421836525906619 0.9031763663884804 0.10578465434494932 0.076173004785161 509.4713382996556 587136.6090758536 0.0264155049555699 0.023315951541078177 1.6476613311720619e-07 6.783132050598932 0.060992713797818565 AEKDEPGAWEETFK ddPTM_PC-9_AZD4547_30min_R2 1 AEKDEPGAWEETFK 14 1 F5H6X6;Q14697;Q14697-2;E9PKU7 F5H6X6 GANAB Neutral alpha-glucosidase AB 0 92.65 0.016386 0.0 8860.1 7495.3 10572.0 12835.0 9836.9 12735.0 10869.0 12731.0 9112.1 11163.0 False True 11677.427498471454 9918.009146419821 10431.808372377916 9876.089048773256 8471.216232253762 11938.678436813276 11836.319943957013 10763.716479276327 9593.747003279153 10772.186767752764 1.0840350014565832 0.9207052718497252 0.9684021078808444 0.9168137595179806 0.7863970811955187 1.1082873602370578 1.0987852512351346 0.9992136890439187 0.8906034782091463 1.0 13.395023528108695 -6.793617319158848 24.999977880865163 1.0242916879238448 0.9352763207062638 0.18448864425113687 0.0881140590526677 347.8394263837882 270244.21081377694 0.032335441456486785 0.02851942468375806 1.6083578416799811e-07 6.793617319158848 -0.08901536721758108 AEKDEPGAWEETFK ddPTM_PC-9_Lapatinib_30min_R1 2 AEKDEPGAWEETFK 14 1 F5H6X6;Q14697;Q14697-2;E9PKU7 F5H6X6 GANAB Neutral alpha-glucosidase AB 0 ; 162.88 4.4211999999999996e-05 8628100.0 71215.0 65935.0 70003.0 57421.0 60121.0 59484.0 61880.0 59772.0 65495.0 50688.0 False True 70199.4610407683 65782.33155853445 64247.62355939438 61643.93189084075 56584.80098243378 56940.00798397662 65083.843618834595 62549.22532841397 58118.263407074555 59449.353262485514 1.1808280021284345 1.1065272866483016 1.0807119006950867 1.0369150967659069 0.9518152490674888 0.9577902005522342 1.0947779924782568 1.0521430746646083 0.9776096831611637 1.0 15.859373494817604 -5.224666953691489 1.28394791703305 1.0106219593998846 1.186335973832596 0.6358856097742045 0.04221690194121448 0.5188207428815939 1.2413280975404826 0.01455236055085652 0.09741690919605334 5.961191126421439e-06 5.224666953691489 0.1757140144327114 AELAS(ph)PLNEADGHR ddPTM_PC-9_AZD4547_30min_R2 2 AELASPLNEADGHR 14 0 Q9BXC9;H3BRL0 Q9BXC9 BBS2 Bardet-Biedl syndrome 2 protein 1 AELAS(1)PLNEADGHR;AELAS(1)PLNEADGHR 90.385 0.0028065 8069500.0 19789.4 24962.0 27311.0 43622.0 48866.0 55426.0 45067.0 50436.0 37345.0 43654.0 True False 26082.017554909206 33030.47834148487 26948.838295309615 33565.62185318169 42081.79938855864 51960.2034580929 49077.87569365264 42642.2751039809 39318.98045867142 42125.68674724348 0.6191475930446617 0.7840935280098725 0.6397246045388928 0.7967970244515498 0.9989581805764219 1.2334565313998815 1.1650344358330034 1.012263025166497 0.9333730437342789 1.0 15.362412585339888 -6.220628526726359 2.775788751232769 1.07821744253479 0.6942236932030099 0.7835384467207963 0.09096990426799294 0.12971253824477774 1.985841397135742 0.030942909538140738 0.040015388214342563 6.016881707102141e-07 6.220628526726359 -0.38399374933178 AELAS(ph)PLNEADGHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AELASPLNEADGHR 14 0 Q9BXC9;H3BRL0 Q9BXC9 BBS2 Bardet-Biedl syndrome 2 protein 1 AELAS(1)PLNEADGHR;AELAS(1)PLNEADGHR 78.848 0.0076325 5274000.0 29973.0 27452.0 34295.0 41716.0 62994.0 47670.0 52446.0 39932.0 49213.0 36391.0 True False 35046.83690626545 30177.253136052444 35112.72286451178 39378.78776509675 50650.7779062127 45170.1012817611 47477.93520384154 38883.82731145132 49932.64702315106 42988.40022900253 0.815262645726946 0.7019859537758066 0.8167952907636383 0.9160328729453272 1.178242912887944 1.0507509244618658 1.1044359629789178 0.9045190587301264 1.1615376882404553 1.0 15.39165980239384 -5.911275999437978 2.806075612173719 1.0627040097281395 0.765171565167216 0.7225739832846143 0.08018117615693705 0.13207180101541724 2.1026654344085696 0.0231602636913315 0.03686416453988149 1.2266594263765706e-06 5.911275999437978 -0.29753244456092354 AELAS(ph)PLNEADGHR ddPTM_PC-9_Lapatinib_30min_R1 2 AELASPLNEADGHR 14 0 Q9BXC9;H3BRL0 Q9BXC9 BBS2 Bardet-Biedl syndrome 2 protein 1 AELAS(1)PLNEADGHR;AELAS(1)PLNEADGHR 129.42 1.283e-05 6036600.0 27785.0 25081.7 27104.1 20878.5 51803.0 48642.0 44841.0 47561.0 45182.0 37357.0 True False 27388.78080485505 25023.62486466505 24875.705522851633 22413.974538634277 48756.049388616586 46561.69505004016 47162.64757130194 49770.85768996682 40093.12737244741 43814.107674926396 0.6251132856125446 0.5711316786438944 0.5677556121287234 0.5115698054364616 1.1127933895255004 1.0627101068792537 1.0764260662620277 1.1359550686102253 0.915073466060604 1.0 15.419107856580624 -6.261709146736961 24.999996044574168 1.0591982880629243 0.5689713016428307 0.9332172673727906 0.06308930180773305 5.420687266574577 502344.53288166795 0.018604593601593052 0.0224484447470449 5.473824300551035e-07 6.261709146736961 -0.49022698642009355 AELDLQT(ph)EPPFSK ddPTM_PC-9_AZD4547_30min_R2 1 AELDLQTEPPFSK 13 0 Q5TA12;Q5JWR5 Q5TA12 DOPEY1 Protein dopey-1 1 AELDLQT(0.999)EPPFS(0.001)K 97.273 0.0074556 0.0 5058.8 3369.1 5792.8 7354.1 6399.4 5651.6 5498.3 3568.6 7399.5 6802.1 True False 6667.393170423294 4458.095688658624 5715.983687051723 5658.725864712378 5510.953771684653 5298.204558578247 5987.638048381526 3017.154868270008 7790.622463621347 6563.9605493981035 1.015757654276986 0.6791777091145709 0.8708132299143483 0.8620901698184745 0.8395775279590904 0.8071658137957696 0.9121989694058376 0.4596546316151569 1.1868783191172174 1.0 12.680350852679046 -8.314232714435347 24.999805368392273 1.0934394346093066 0.8103435617935659 0.37814287869480023 0.14745093172619778 379.52324305548666 179716.3496014633 0.13172355010002543 0.03401098128934416 4.850285305056948e-09 8.314232714435347 -0.28309587281574067 AELDLQT(ph)EPPFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AELDLQTEPPFSK 13 0 Q5TA12;Q5JWR5 Q5TA12 DOPEY1 Protein dopey-1 1 AELDLQT(1)EPPFSK 117.7 0.00068927 0.0 4270.9 5785.7 5516.3 5557.9 8117.1 8573.0 7415.1 6760.2 5363.1 5743.7 True False 4993.879015879931 6360.066059640771 5647.82951268425 5246.508881954916 6526.6125240899 8123.416788096032 6712.688047324976 6582.751913023972 5441.525191511624 6784.98734289582 0.7360189140380258 0.9373733123172351 0.8324008914471707 0.7732525672945053 0.9619196314232701 1.1972633665413697 0.9893442254322634 0.9701936909162259 0.8019948920330913 1.0 12.728130409022729 -6.3841760712349584 5.737045224828633 0.9986435669408205 0.8299526074255934 0.39330664198091037 0.10145064741484394 0.25971192053315795 11.125317962084306 0.03317102108754153 0.037626008750453487 4.128800786251717e-07 6.3841760712349584 -0.16869095951522706 AELDLQT(ph)EPPFSK ddPTM_PC-9_Lapatinib_30min_R1 1 AELDLQTEPPFSK 13 0 Q5TA12;Q5JWR5 Q5TA12 DOPEY1 Protein dopey-1 1 AELDLQT(0.992)EPPFS(0.008)K 78.40100000000001 0.041828 0.0 7807.1 8847.9 7931.2 6291.8 7406.4 6283.3 7437.7 6460.8 7710.8 5813.0 True False 7695.769322353203 8827.413231163351 7279.127351317355 6754.519960829515 6970.770113542649 6014.577906087687 7822.787713054401 6760.992354309995 6842.328505676315 6817.769304664381 1.12878112744122 1.2947656097902978 1.0676699410080266 0.9907228682860252 1.0224414763892924 0.8821914672256231 1.1474116185923797 0.9916722101002241 1.0036022340907211 1.0 12.73508406796988 -5.449050861517427 4.941499951424863 1.0077470840774048 1.2098928583621773 0.5691629222574706 0.07079197284874408 0.1435923284929347 6.418604331926881 0.01809613069663725 0.038317642006575 3.5558967196711666e-06 5.449050861517427 0.20214577428477254 AELGMGDSTS(ph)QSPPIKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AELGMGDSTSQSPPIKR 17 1 Q9NR19;Q9NR19-2 Q9NR19 ACSS2 Acetyl-coenzyme A synthetase, cytoplasmic 1 AELGMGDS(0.034)T(0.119)S(0.538)QS(0.309)PPIKR 47.81399999999999 0.036644 5090000.0 26827.0 32293.0 31159.0 35985.0 35724.0 31823.0 32098.0 30657.0 30557.0 27839.0 True False 31368.281242597805 35498.835622998005 31901.94873116555 33968.87711494407 28724.138646879746 30154.145858810225 29057.445070604157 29852.286233776485 31003.83831683552 32885.990326597275 0.9538493726682152 1.0794516227260316 0.9700771791982236 1.03292851386236 0.8734460589939559 0.9169298403163 0.8835812691674759 0.907750867080709 0.9427673610838618 1.0 15.005185495701614 -6.254523016461351 24.89665088532576 0.9140844078272412 1.0113177795199502 0.46816466667360934 0.045767871685477135 401.3234722352914 1444633.0639442687 0.012734421472342819 0.016073349026327257 5.565151396430496e-07 6.254523016461351 0.09723337169270896 AELGMGDSTSQS(ph)PPIKR ddPTM_PC-9_AZD4547_30min_R2 1 AELGMGDSTSQSPPIKR 17 1 Q9NR19;Q9NR19-2 Q9NR19 ACSS2 Acetyl-coenzyme A synthetase, cytoplasmic 1 AELGMGDS(0.044)T(0.121)S(0.169)QS(0.666)PPIKR 44.047 0.045956 41367000.0 54688.0 52397.0 77049.0 110120.0 87123.0 81132.0 82784.0 89300.0 72553.0 73424.0 True False 72077.64641893524 69333.30557081889 76027.27991707782 84733.5353370401 75027.47530244742 76058.80321441179 90151.61562614204 75500.73690985584 76388.00346011494 70853.4481085263 1.0172778932160624 0.9785452567477168 1.0730215952317064 1.1958985426828297 1.0589107136681304 1.0734665036754802 1.2723673728349356 1.0655901572244062 1.0781127171554354 1.0 16.11255044367404 -5.437937512954435 4.797200219067039 1.1141059032632648 1.0003516439873654 0.24749510480312897 0.07350231571115107 0.2767905636760032 10.936755638827316 0.01931310464279851 0.04120191480571184 3.648064321337667e-06 5.437937512954435 -0.11375425927589933 AELGMGDSTSQS(ph)PPIKR ddPTM_PC-9_Lapatinib_30min_R1 3 AELGMGDSTSQSPPIKR 17 1 Q9NR19;Q9NR19-2 Q9NR19 ACSS2 Acetyl-coenzyme A synthetase, cytoplasmic 1 AELGMGDS(0.029)T(0.029)S(0.024)QS(0.918)PPIKR;AELGMGDS(0.009)T(0.102)S(0.08)QS(0.809)PPIKR;AELGMGDS(0.224)T(0.049)S(0.224)QS(0.503)PPIKR 72.289 0.007597399999999999 46362200.0 134264.0 129981.0 133849.0 132047.0 119048.0 138014.0 125198.0 107326.0 131377.0 89402.0 True False 132349.37073899765 129680.03698050915 122844.4518920815 141758.1768758789 112045.83069737337 132111.46294634754 131680.13984148108 112312.757772826 116579.93879885836 104855.01657932297 1.262213054335604 1.2367556766576449 1.1715648511595007 1.3519446326980327 1.068578636985008 1.2599441329200023 1.2558306139016713 1.071124314666063 1.1118203267906164 1.0 16.678036360391864 -7.768333125154141 24.99458701758835 1.0686041700598443 1.227280107729339 0.5258955902359166 0.07321494543518896 133.26586279618584 483171.0521832575 0.03731380337307102 0.01854047182993849 1.704774241959378e-08 7.768333125154141 0.15867593766949462 AELGSWS(ph)SQEHLEWEPACQTPQPSAR ddPTM_PC-9_Lapatinib_30min_R1 1 AELGSWSSQEHLEWEPACQTPQPSAR 26 0 H3BTL6;B7Z896;F5H3M2;Q9BVG8-5;Q9BVG8-2;Q9BVG8;Q9BVG8-6 H3BTL6 KIFC3 Kinesin-like protein;Kinesin-like protein KIFC3 1 AELGS(0.085)WS(0.455)S(0.455)QEHLEWEPACQT(0.003)PQPS(0.002)AR 43.903999999999996 0.028535 2940600.0 5424.1 6101.3 5328.6 4592.3 7542.8 5276.8 6434.6 5475.9 6974.0 4865.0 True False 5346.751339341882 6087.172814712758 4890.503076990833 4930.033061463711 7099.147333715368 5051.1235648215925 6767.7521032604 5730.330304755774 6188.51468052428 5705.908767794979 0.9370551750704048 1.0668191628071046 0.8570945095711272 0.8640224129221222 1.244174700756528 0.8852443616573237 1.1860953931578133 1.0042800433646317 1.0845800261394298 1.0 12.478240964406467 -6.219065289268122 24.990857005906072 1.06443743979213 0.9356348283085547 0.27678628286627016 0.10765753543584788 676.2165364408673 398810.21245942294 0.030331648577519046 0.039157657742484815 6.038578421298282e-07 6.219065289268122 -0.1288026114835752 AELLQSDENGIPS(ph)SPQK ddPTM_PC-9_AZD4547_30min_R2 1 AELLQSDENGIPSSPQK 17 0 Q14542-3;Q14542 Q14542-3 SLC29A2 Equilibrative nucleoside transporter 2 1 AELLQSDENGIPS(0.953)S(0.047)PQK 181.51 1.1962999999999999e-06 5229700.0 14025.0 37726.0 26015.0 25766.0 26221.0 17662.0 24712.0 29957.0 20228.0 16569.0 True False 18484.65826187764 49920.19172786066 25670.024102100953 19826.04678073172 22580.666757405877 16557.592347938455 26911.3201265126 25327.833993376844 21297.21078371953 15988.924353211087 1.1560914201314194 3.1221732384914995 1.6054878699170023 1.239986276922376 1.41226928457329 1.0355663697047364 1.6831226123793592 1.5840861732696987 1.3319977199993676 1.0 13.964785265053983 -5.507207460045913 24.560615724683483 1.3623693022571537 2.1953069766948397 0.30292194625043856 0.484519639559343 570.6119370146644 894282.1252660794 0.11824169977763328 0.23453846530831413 3.110230242586826e-06 5.507207460045913 0.832937674437686 AELLQSDENGIPSS(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 1 AELLQSDENGIPSSPQK 17 0 Q14542-3;Q14542 Q14542-3 SLC29A2 Equilibrative nucleoside transporter 2 1 AELLQSDENGIPS(0.399)S(0.601)PQK 128.82 3.1487e-05 6249400.0 15195.0 35213.0 19372.0 21403.0 23020.0 15715.0 24721.0 27119.0 26036.0 16658.0 True False 20026.69392436584 46594.91362225406 19115.11462256006 16468.869023053674 19824.070354123938 14732.33856572601 26921.121109077296 22928.38168262466 27412.20980645252 16074.808490300595 1.2458433913193916 2.8986294704766804 1.18913482758404 1.0245141665601087 1.2332383534202362 0.9164861015056808 1.6747397721920778 1.4263548891708073 1.7052899773576038 1.0 13.972513929436145 -5.3186841338265705 24.999964695393178 1.2780213537825897 2.072242651209073 0.3379983119949843 0.4483274127678954 254.23698362604398 111029.97497544532 0.11143938601882147 0.2319797049640128 4.800824898828545e-06 5.3186841338265705 0.7942212974264833 AELNEFLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AELNEFLTR 9 0 P23396;P23396-2;E9PL09;F2Z2S8;H0YCJ7;E9PPU1;H0YF32;E9PQ96;E9PJH4;E9PK82;H0YEU2;E9PQX2;H0YES8 P23396 RPS3 40S ribosomal protein S3 0 91.63600000000001 0.035236 5661900.0 12444.0 11462.0 15593.0 18094.0 15419.0 11535.0 17613.0 17230.0 13953.0 11255.0 False True 14550.523419796733 12599.871610280963 15964.796256781798 17080.251841539477 12397.757636217633 10930.08429379304 15944.569132922647 16777.730756694025 14157.036228517407 13295.442405469017 1.0943993419738665 0.9476835163527967 1.2007720969265945 1.2846696876001356 0.9324817676708429 0.8220925607783461 1.1992507392130045 1.2619159442029988 1.064803697144668 1.0 13.698644163180315 -10.543622271128154 4.555226358301217 0.999996879503622 1.0903845402486594 0.03351120537386676 0.14462190539160663 4.918544648514094e-06 1.0576496476613214e-06 0.14988787518924648 0.03635189115534737 2.8600770221041816e-11 10.543622271128154 0.09038766074503735 AELNEFLTR ddPTM_PC-9_Lapatinib_30min_R1 3 AELNEFLTR 9 0 P23396;P23396-2;E9PL09;F2Z2S8;H0YCJ7;E9PPU1;H0YF32;E9PQ96;E9PJH4;E9PK82;H0YEU2;E9PQX2;H0YES8 P23396 RPS3 40S ribosomal protein S3 0 ;; 117.31 0.0085963 25643200.0 63813.0 55602.0 65143.0 58313.0 62436.0 64947.0 61387.0 51050.0 64301.0 55057.0 False True 62903.01491812901 55473.25698517673 59787.193999251875 62601.53254646552 58763.63723389891 62169.36820885162 64565.31849110215 53421.96936718756 57058.744260451975 64573.52909115888 0.9741300468389826 0.8590711668687763 0.9258777527065293 0.9694612239341993 0.9100267255169203 0.9627686311071323 0.9998728488256367 0.8273044716476841 0.8836243746241864 1.0 15.978655255375347 -4.44393341688003 21.552267968820292 0.9247804079285861 3.456669974261863 0.062219844557734105 0.05519809721029277 1021.4492968457605 278282.71060782264 0.01346099494628892 260.0594002216468 3.5980449374146765e-05 4.44393341688003 2.5318895663332768 AELPGS(ph)SSPLLAQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AELPGSSSPLLAQPR 15 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 AELPGS(0.388)S(0.306)S(0.306)PLLAQPR 87.51899999999999 0.022857 0.0 11153.0 11112.0 14487.0 13040.0 15623.0 13961.0 16158.0 13340.0 10801.0 9990.7 True False 13040.982618209011 12215.125923350372 14832.425022253457 12309.411076250413 12561.78530064389 13228.860583064128 14627.39726621043 12989.839134898337 10958.944191515551 11801.934823662321 1.104986835892574 1.0350104542909033 1.2567790996875485 1.0429994115516235 1.0643835513697386 1.1209060870714935 1.2394067146416696 1.100653352944665 0.9285718278619355 1.0 13.526735775719667 -8.193204860985276 5.904453811782684 0.9650590114779982 1.1226732892404407 0.42962504849127825 0.07223234142738587 0.19373847344843226 12.59493486748736 0.051539273073498953 0.018661831603062562 6.4090718303805334e-09 8.193204860985276 0.15761427776244252 AELPGS(ph)SSPLLAQPR ddPTM_PC-9_Lapatinib_30min_R1 1 AELPGSSSPLLAQPR 15 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 AELPGS(0.417)S(0.291)S(0.291)PLLAQPR 104.7 0.0011242000000000001 7283000.0 41623.0 41922.0 36884.0 36339.0 33680.0 33201.0 24934.0 27558.0 39551.0 22357.0 True False 41029.44838727664 41824.93218468 33851.53989635734 39011.49128335035 31699.0086174277 31781.07062531114 26224.96051700102 28838.445285425154 35096.349889506164 26221.377661170045 1.5647327504090354 1.5950699740165253 1.2909901353690667 1.4877742804917744 1.2088994341578478 1.2120290183064701 1.0001366387333752 1.0998066409047071 1.338463231910146 1.0 14.678455865746978 -5.928631563267667 0.7226670786879014 1.1068269367328984 1.616621011245985 0.6883485724180927 0.11521206136225456 0.5385594993034671 0.5324393119337195 0.06236668931777601 0.17699902268852763 1.1786054275933541e-06 5.928631563267667 0.5097940745130864 AELPGSS(ph)SPLLAQPR ddPTM_PC-9_AZD4547_30min_R2 1 AELPGSSSPLLAQPR 15 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 AELPGS(0.247)S(0.617)S(0.137)PLLAQPR 85.163 0.005878 7762000.0 16886.0 21937.0 28574.0 36998.0 33486.0 34860.0 28340.0 43858.0 34381.0 36355.0 True False 22255.39674938083 29027.706248583978 28195.09009008005 28468.682713401864 28837.04691043415 32680.198689227396 30862.205098145343 37080.75385657849 36198.30946979736 35082.22251560077 0.6343781879692497 0.8274192501822141 0.8036859716496563 0.8114845831315869 0.8219846076630566 0.9315315948040289 0.8797106592782479 1.0569670675821348 1.0318134620376538 1.0 15.098452527294116 -6.746571478128134 0.5268336318706532 1.046089077343293 0.716863646843983 0.785630784235582 0.05640227386319299 0.4530437549734639 0.2698566465508949 0.04944966501847998 0.06363929927173886 1.7923735312364134e-07 6.746571478128134 -0.32922543049930997 AELPGSS(ph)SPLLAQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AELPGSSSPLLAQPR 15 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 AELPGS(0.1)S(0.45)S(0.45)PLLAQPR;AELPGS(0.083)S(0.458)S(0.458)PLLAQPR;AELPGS(0.077)S(0.461)S(0.461)PLLAQPR 207.08 6.021699999999999e-13 14645800.0 53527.0 73345.0 86597.0 74615.0 94517.0 81584.0 86138.0 79453.0 70495.0 51160.0 True False 62588.0638935599 80626.20687978159 88661.80090095154 70434.56345509372 75997.07234596144 77305.59141957619 77978.38505488512 77367.44293741224 71525.85601156279 60434.903017662815 1.0356277708473827 1.3341000457337977 1.4670628473589025 1.165461677575761 1.2575030082161363 1.279154719533226 1.2902872539084742 1.2801781598756052 1.1835190004467868 1.0 15.883094370607797 -8.641799314628834 2.5459860425641123 1.0002007960188843 1.2706080754734097 0.36664594236046244 0.10478521125536355 0.5037596687008545 6.940019167871061 0.10008674001789479 0.027018017989577633 2.281396050499033e-09 8.641799314628834 0.27040727945452536 AELPGSS(ph)SPLLAQPR ddPTM_PC-9_Lapatinib_30min_R1 1 AELPGSSSPLLAQPR 15 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 AELPGS(0.173)S(0.414)S(0.414)PLLAQPR 168.45 0.00020248 7769400.0 42729.0 37566.0 35745.0 29763.0 27715.0 26503.0 23259.0 24234.0 31543.0 21169.0 True False 42119.6766244611 37479.01823504818 32806.18407969022 31951.87030645745 26084.85818978647 25369.528471510523 24463.23721283895 25360.00011056654 27990.295177484564 24828.03344408057 1.696456415661191 1.5095443752909805 1.3213363899149966 1.2869271494426524 1.050621195937109 1.0218098235065434 0.9853070831379682 1.0214260492150578 1.1273665810272997 1.0 14.599682373934504 -5.300408166083546 0.7668882412387719 1.016714584625903 1.8371646854240888 0.9500330775556125 0.052033014619379106 0.3081362403786758 0.22435327337906708 0.02377556214766478 0.1917618466663134 5.007164205297696e-06 5.300408166083546 0.8204501007981859 AELPGSSS(ph)PLLAQPR ddPTM_PC-9_AZD4547_30min_R2 1 AELPGSSSPLLAQPR 15 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 AELPGS(0.08)S(0.373)S(0.547)PLLAQPR 115.09 0.00016543 10106000.0 18569.0 18841.0 39689.0 40875.0 32433.0 36822.0 35519.0 39729.0 33132.0 39520.0 True False 24473.555740806132 24930.98479416377 39162.69792766807 31451.900262454757 27930.23778433106 34519.51451906862 38680.12219057955 33589.79593159758 34883.28987968143 38136.4168289518 0.6417371577034654 0.6537317049470956 1.026910789844765 0.8247209066211382 0.7323770848636054 0.9051588321444675 1.014256854912887 0.8807800712440665 0.9146976244815767 1.0 15.218881678733805 -4.100777945836247 0.725542268705599 0.9144832929969448 5.456301775311181e-22 0.4829796098161224 0.0976498543799103 6.296586709487025 1.2361934665876395 0.04013399310862602 5.914528204710859 7.929066389150142e-05 4.100777945836247 -0.9144832929969448 AELSEGQVR ddPTM_PC-9_Lapatinib_30min_R1 2 AELSEGQVR 9 0 P09493-3;P09493-4;P09493-10;P09493-8;H0YKX5;H7BYY1;P09493-2;B7Z596;F5H7S3;H0YL42 P09493-3 TPM1 Tropomyosin alpha-1 chain 0 ; 117.81 0.0084574 12324100.0 43833.0 50253.0 48694.0 54589.0 62591.0 50458.0 51466.0 53730.0 58801.0 50083.0 False True 43207.93338201227 50136.64226603512 44690.56728427567 58603.65716356565 58909.520438640655 48300.02896334292 54130.657654927956 56226.49195100854 52178.21217801958 58739.77981859734 0.7355821474892965 0.8535381375427217 0.7608228601178105 0.997682615504313 1.0028897047378713 0.8222711953041891 0.9215332066632959 0.9572131888244995 0.8882943099064814 1.0 15.84205023739449 -5.753759498108446 24.99999447955539 0.936398333873505 0.7903367287742097 0.5911473940035217 0.060065669346760636 131.97833391858362 429618.7435181411 0.016557932376854413 0.02799802592822828 1.7629520568032835e-06 5.753759498108446 -0.14606160509929533 AEMVS(ph)SNIRHSPPGERSFSFT(ph)T(ph)VLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEMVSSNIRHSPPGERSFSFTTVLTK 26 2 Q9Y6Y1-2;Q9Y6Y1 Q9Y6Y1-2 CAMTA1 Calmodulin-binding transcription activator 1 3 AEMVS(0.355)S(0.355)NIRHS(0.285)PPGERS(0.012)FS(0.017)FT(0.959)T(0.959)VLT(0.059)K 46.818000000000005 0.031937 0.0 11255.0 11883.0 10237.0 14348.0 12663.0 12609.0 14005.0 13379.0 12674.0 11946.0 True False 13160.249203617179 13062.665707988881 10481.088904038688 13544.128076843625 10181.776052106103 11947.761843124104 12678.345012580581 13027.81542622226 12859.333273147673 14111.715235516025 0.9325761598771339 0.9256610900929377 0.7427225343706012 0.9597790099077459 0.7215122954352745 0.8466555371705818 0.8984269311693611 0.9231914908142539 0.9112523218144037 1.0 13.784605733280456 -8.30473885247028 0.973074622916783 0.9924801789529836 0.854782825996685 0.2498713414067223 0.07424717824878405 0.7313928834264315 1.4649866616981877 0.06958537330929389 0.024196602540025976 4.957482017336193e-09 8.30473885247028 -0.1376973529562986 AENGERS(ph)DLEEDNER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AENGERSDLEEDNER 15 1 Q8WU90 Q8WU90 ZC3H15 Zinc finger CCCH domain-containing protein 15 1 AENGERS(1)DLEEDNER 66.059 0.015401 2016500.0 4945.9 8577.8 7542.9 5015.0 6575.4 5104.4 5809.1 4686.3 4630.0 4983.7 True False 5783.143184022229 9429.34729529471 7722.75134260755 4734.025808849371 5286.997571903847 4836.716278217356 5258.819993758072 4563.289590545285 4697.704990900565 5887.20535905251 0.9823240113630028 1.6016678067456227 1.3117856218031527 0.8041210591660536 0.8980487768741158 0.8215640500428849 0.8932625368115966 0.7751198254921591 0.7979516093620039 1.0 12.523367237660006 -5.756899535278631 24.51436555681366 0.8482582564411121 1.3289002154641494 0.6370385992905225 0.15260434116419844 48.5900304860574 262372.1476068369 0.03945800454686088 0.06546072815608939 1.7502515249798012e-06 5.756899535278631 0.4806419590230373 AENGLLMT(ph)PCYTANFVAPEVLKR ddPTM_PC-9_AZD4547_30min_R2 4 AENGLLMTPCYTANFVAPEVLKR 23 1 B4DG22;B1AXG1;B7ZB17;P51812;A0A2R8Y603;E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2 B4DG22;E9PGT3 RPS6KA3;RPS6KA1 Ribosomal protein S6 kinase alpha-3;Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 AENGLLMT(0.998)PCY(0.002)TANFVAPEVLKR;AENGLLMT(0.966)PCY(0.027)T(0.007)ANFVAPEVLKR;AENGLLMT(1)PCYTANFVAPEVLKR;AENGLLMT(0.973)PCY(0.027)TANFVAPEVLKR 127.58 3.2096e-08 49394600.0 194300.0 143648.0 193419.0 310978.0 233390.0 171230.0 120743.0 172256.0 134602.0 175916.0 True False 256083.35830893647 190079.40681025616 190854.13768227032 239286.82666220554 200987.82710464715 160522.96103145197 131488.89308981536 145637.7932490943 141716.7869245709 169757.23438466323 1.5085269222085795 1.1197131450642255 1.1242769026844672 1.4095824989702117 1.1839720871583983 0.94560306436021 0.774570188813672 0.8579180367599815 0.8348203093568679 1.0 17.373113532196847 -6.769634620176542 3.0566088132654428 0.8557145849828237 1.2693500056110287 0.7188952295678399 0.12247609288683062 0.1363165959687104 2.628504380164034 0.04456263346317763 0.04124773540957748 1.6996730168346004e-07 6.769634620176542 0.413635420628205 AENGLLMT(ph)PCYTANFVAPEVLKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AENGLLMTPCYTANFVAPEVLKR 23 1 B4DG22;B1AXG1;B7ZB17;P51812;A0A2R8Y603;E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2 B4DG22;E9PGT3 RPS6KA3;RPS6KA1 Ribosomal protein S6 kinase alpha-3;Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 AENGLLMT(0.904)PCY(0.083)T(0.013)ANFVAPEVLKR;AENGLLMT(0.674)PCY(0.273)T(0.054)ANFVAPEVLKR 78.27199999999999 0.00012529999999999998 21649000.0 29390.0 25471.0 36160.0 63730.0 99365.0 119833.0 106330.0 139983.0 129896.0 103800.0 True False 34365.14652104032 27999.592548025346 37022.191537563645 60159.41471544774 79895.14154762082 113548.74652605985 96257.65263746466 136308.59457424833 131795.48326091154 122618.11831965207 0.2802615713891003 0.22834792224615175 0.30193084060424763 0.4906241878432574 0.6515769662958201 0.9260356306402504 0.7850198156403889 1.1116513321376102 1.0748450968504921 1.0 16.903812644971403 -6.426364993017254 0.8154278861535768 1.051561759852922 0.20657075720242574 0.9458272125106952 0.07575386583515623 0.1318755904497243 0.19315838244009284 0.043698906099244844 0.06067729967259901 3.746579970179886e-07 6.426364993017254 -0.8449910026504963 down AENGLLMT(ph)PCYTANFVAPEVLKR ddPTM_PC-9_Lapatinib_30min_R1 3 AENGLLMTPCYTANFVAPEVLKR 23 1 B4DG22;B1AXG1;B7ZB17;P51812;A0A2R8Y603;E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2 B4DG22;E9PGT3 RPS6KA3;RPS6KA1 Ribosomal protein S6 kinase alpha-3;Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 AENGLLMT(0.947)PCY(0.049)T(0.004)ANFVAPEVLKR;AENGLLMT(0.933)PCY(0.058)T(0.008)ANFVAPEVLKR;AENGLLMT(0.916)PCY(0.075)T(0.01)ANFVAPEVLKR 77.575 0.00025469 10751400.0 25507.6 19921.1 21172.7 22878.7 41308.3 61840.0 58315.0 52665.0 87006.0 66400.0 True False 25143.85694647906 19874.973916898733 19431.962334985514 24561.275919105858 38878.627009242526 59195.24735608085 61334.26536251357 55112.008163034865 77206.46806620235 77877.15152756145 0.3228656474111077 0.2552093075703314 0.24952071247891444 0.3153848778150725 0.4992302138257203 0.7601105869303797 0.7875771540104006 0.7076787874493613 0.9913879302439337 1.0 16.248912495859642 -6.684022302196834 1.090604588006036 0.8843510293396012 0.25304756001005524 0.9205852162663513 0.07940974510942131 0.13004301157651474 0.3303812084305023 0.04155192490491191 0.04058815199648637 2.0700350441605763e-07 6.684022302196834 -0.631303469329546 down AENLQLLTENELHR ddPTM_PC-9_Lapatinib_30min_R1 2 AENLQLLTENELHR 14 0 O94992 O94992 HEXIM1 Protein HEXIM1 0 ; 79.652 0.01051 3882000.0 30318.0 26759.0 32662.0 31397.0 29779.0 29752.0 23893.0 26190.0 30152.0 26181.0 False True 29885.659760359715 26697.04117956807 29976.656438966063 33706.040117321645 28027.45776776661 28479.576315299448 25130.062630653134 27406.883011295624 26755.964245363946 30706.350966010355 0.9732729165194821 0.8694306011521755 0.9762363646578517 1.0976895351268448 0.9127576832164433 0.9274816257660905 0.8183995115039961 0.8925477026440883 0.8713495222854974 1.0 14.906249457280612 -6.502311097580158 24.747045362855072 0.8933622899534684 0.975375153389999 0.22900284880573651 0.06695565035107226 1007.1932233278294 1211858.683346661 0.021563762205541903 0.02415842516843828 3.14549429920335e-07 6.502311097580158 0.08201286343653058 AENSHNAGQVDTR ddPTM_PC-9_Lapatinib_30min_R1 2 AENSHNAGQVDTR 13 0 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;E9PDP5;D6RHC4;Q8IWZ3-5;Q8IWZ3-3;Q8IWZ3-2 Q8IWZ3-6 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 0 ; 86.738 0.0062495 1978980.0 7243.6 6832.1 6102.4 6294.9 6464.7 7358.0 5969.0 4538.0 6327.0 6942.7 False True 7140.304935686447 6816.280692212977 5600.684227945208 6757.84794517081 6084.4590560892175 7043.315492335753 6278.045613458692 4748.852046783484 5614.386633736329 8142.736444433747 0.8768925513446345 0.8370995105548926 0.6878135214328043 0.8299234527958195 0.7472253458784684 0.8649813905189647 0.7709994860204852 0.5832010011855079 0.6894962979643335 1.0 12.991297992099891 -7.531944802100741 24.99383462054492 0.7172292454209613 0.8029104285959927 0.002403380925317 0.11236764140563552 468.51422385513933 1291607.2246069456 0.050181803380498505 0.029023465422065953 2.9380230446739268e-08 7.531944802100741 0.08568118317503137 AENYDIPSADR ddPTM_PC-9_AZD4547_30min_R2 1 AENYDIPSADR 11 0 P22314;P22314-2;Q5JRR6 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 128.01 0.0015260999999999999 6296700.0 30645.0 28856.0 50277.0 60122.0 47763.0 46265.0 31826.0 55574.0 33545.0 37950.0 False True 40389.47254440218 38183.137690164534 49610.29412959178 46261.801775640495 41131.931899392766 43372.04223629106 34658.45234486852 46986.31526347515 35318.1202165252 36621.38205108102 1.1028931810401168 1.0426460049187962 1.3546811002488461 1.2632456555329512 1.1231671115530333 1.1843365762601188 0.9463993547956623 1.2830295480912408 0.9644125436681235 1.0 15.160398617451957 -7.1235478009278435 18.576578081282417 1.0710534942224954 1.1817136393278451 0.2126557803150858 0.11935195554369638 5.1486442414228195 753.5796508501174 0.04582954079810048 0.03549949651707334 7.524059115296629e-08 7.1235478009278435 0.11066014510534972 AENYDIPSADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AENYDIPSADR 11 0 P22314;P22314-2;Q5JRR6 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 98.898 0.017594 0.0 18658.0 18698.0 26244.0 20869.0 26561.0 20902.0 24440.0 20870.0 21456.0 16007.0 False True 21816.430887702314 20554.21386922294 26869.75649092423 19699.777588210873 21356.56271973386 19805.86232413196 22124.866269722912 20322.18461359284 21769.75340923596 18908.942388657728 1.153762618727349 1.087010232870142 1.421007898730586 1.041823343860179 1.1294424765154663 1.0474336383832994 1.1700742333952117 1.0747393585472462 1.151294078842519 1.0 14.206781052551108 AENYDIPSADR ddPTM_PC-9_Lapatinib_30min_R1 2 AENYDIPSADR 11 0 P22314;P22314-2;Q5JRR6 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 ; 158.08 0.004325 14907100.0 71768.0 84468.0 90686.0 70198.0 76064.0 79301.0 76138.0 60363.0 87251.0 63298.0 False True 70744.57515936067 84272.41953569828 83230.14713808316 75360.59509366316 71590.0650675778 75909.48108965986 80080.05309390477 63167.68534596554 77423.87358623803 74238.97496071654 0.952930387263497 1.13515063455942 1.1211112112219261 1.0151082384090044 0.9643191477988428 1.0225017402224004 1.0786794017061663 0.8508695786733402 1.042900627698682 1.0 16.179889170439232 -5.938744383793432 6.849323128266949 0.9913099980768428 1.0757793149612602 0.18075861847954178 0.07244227756137565 0.32962026615596757 29.39788835106578 0.020238044654701026 0.030134579877279296 1.1514779241842304e-06 5.938744383793432 0.08446931688441739 AEPASPDS(ph)PKGSSETETEPPVALAPGPAPTR ddPTM_PC-9_AZD4547_30min_R2 1 AEPASPDSPKGSSETETEPPVALAPGPAPTR 31 1 F5GWT5;A0A6E1WCP9;P11474-2;P11474 F5GWT5 ESRRA Steroid hormone receptor ERR1 1 AEPAS(0.05)PDS(0.553)PKGS(0.145)S(0.169)ET(0.054)ET(0.027)EPPVALAPGPAPT(0.001)R 42.181000000000004 0.021644999999999998 5082300.0 11150.0 7434.6 11171.0 11860.0 13037.0 12085.0 8522.4 10583.0 9841.8 8994.9 True False 14695.468065592577 9837.689058473015 11022.865240998271 9125.860235173412 11227.037585000595 11329.32303956722 9280.877089923562 8947.64052314675 10362.017455567078 8679.991288834482 1.693027973944641 1.1333754529371174 1.2699166248216802 1.0513674416830894 1.2934388078755918 1.3052228582464949 1.06922654425495 1.0308351961892588 1.1937820109216322 1.0 13.083477879456082 -4.759826658073112 24.98794839741971 1.158171918106385 1.6930286383814364 0.6976984212082803 0.10716456126691992 23.705422134555135 367182.2673233628 0.02686021071421568 0.1660370880862564 1.738494583519819e-05 4.759826658073112 0.5348567202750514 AEPDESNAR ddPTM_PC-9_AZD4547_30min_R2 2 AEPDESNAR 9 0 F8VSD4;F8VV71;P61088;Q5JXB2;F8VZ29 F8VSD4 UBE2N;UBE2NL Ubiquitin-conjugating enzyme E2 N;Putative ubiquitin-conjugating enzyme E2 N-like 0 ; 107.69 0.011451000000000001 8468400.0 41028.0 31942.0 61143.0 88826.0 69435.0 56765.0 44574.0 61017.0 51439.0 55367.0 False True 54074.05056458583 42266.62684014541 60332.20386987352 68348.53804801969 59795.14878534289 53215.475576419805 48540.9996487202 51588.22468117223 54157.96052520016 53428.61818240321 1.0120802746569102 0.7910859063554442 1.129211383755083 1.279249592693572 1.119159559418224 0.9960107033789318 0.9085205887789036 0.9655541624724796 1.0136507805668302 1.0 15.705325084953195 -6.946461765239508 7.413090879150148 0.9666849790618615 1.065798495758472 0.12881237214751928 0.117256928684024 0.5314227216548981 61.51100197126682 0.04704186960665455 0.04137104160957098 1.1311969741623164e-07 6.946461765239508 0.09911351669661062 AEPDESNAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AEPDESNAR 9 0 F8VSD4;F8VV71;P61088;Q5JXB2;F8VZ29 F8VSD4 UBE2N;UBE2NL Ubiquitin-conjugating enzyme E2 N;Putative ubiquitin-conjugating enzyme E2 N-like 0 ; 104.2 0.012528000000000001 5450400.0 25514.0 35338.0 64947.0 55837.0 72104.0 75288.0 51763.0 56121.0 57958.0 49389.0 False True 29833.016275529866 38846.12309929406 66495.58279286907 52708.633915996485 57975.73880289483 71339.76474305072 46859.63390833335 54647.88321511471 58805.52610423646 58342.83473689113 0.5113398485018412 0.6658250884530816 1.1397386344483331 0.9034294297439742 0.9937079517021793 1.2227682296338855 0.8031771873899579 0.9366682894576591 1.0079305602724298 1.0 15.832267864542827 -5.095360272230174 4.466305749149297 0.9948124085079066 0.5412825019137983 0.6935131184312353 0.11145398706491533 0.11367804069872406 3.7665492263859743 0.028754622543079537 0.08748105336743914 8.028598274944136e-06 5.095360272230174 -0.4535299065941083 AEPDESNAR ddPTM_PC-9_Lapatinib_30min_R1 2 AEPDESNAR 9 0 F8VSD4;F8VV71;P61088;Q5JXB2;F8VZ29 F8VSD4 UBE2N;UBE2NL Ubiquitin-conjugating enzyme E2 N;Putative ubiquitin-conjugating enzyme E2 N-like 0 ; 95.35799999999999 0.025119 12654300.0 38295.0 34048.0 39098.0 37471.0 42531.0 39145.0 33079.0 34798.0 43686.0 31498.0 False True 37748.906277557086 33969.16394790287 35883.51336264448 40226.74233959166 40029.41019916321 37470.85960145186 34791.66876320992 36414.842116344604 38765.62264602577 36942.38733155317 1.0218318036342782 0.9195172916962295 0.9713371537306068 1.0889047851337228 1.083563166611416 1.0143053091061962 0.9417818196468781 0.9857197855007606 1.0493534783799785 1.0 15.17298948030681 -5.5574001131284865 24.98760704776846 1.0221729882718769 0.9643625987393929 0.20111098095889912 0.047560061602742905 277.00918725089525 200506.44726146752 0.01407528784678089 0.024379281378354694 2.770766236635848e-06 5.5574001131284865 -0.05781038953248396 AEPEDHYFLLTEPPLNTPENR ddPTM_PC-9_Lapatinib_30min_R1 2 AEPEDHYFLLTEPPLNTPENR 21 0 P61158;F8WDR7;B4DXW1 P61158 ACTR3 Actin-related protein 3 0 ; 133.09 2.8793e-05 7376700.0 39113.0 37164.0 51976.0 43517.0 49926.0 45094.0 46415.0 41281.0 48181.0 41167.0 False True 38555.24144755427 37077.94904134933 47702.73391316205 46717.385348456424 46989.450838292614 43165.43473924824 48818.14158966078 43199.06596369965 42754.34841157735 48282.66109842052 0.7985318242704633 0.7679350764401482 0.9879889141968308 0.9675809966900251 0.9732158453840853 0.8940152377115005 1.0110905339320202 0.8947117864038532 0.8855010771760462 1.0 15.559217571957529 -5.256534662035229 24.99859885767969 0.9493902716615217 0.7832334322074754 0.701013644464993 0.044003100107156905 215.90145881548077 1100407.4593399295 0.011289101603820182 0.027947733760528257 5.539433306909163e-06 5.256534662035229 -0.16615683945404625 AEPSEVDMNS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 6 AEPSEVDMNSPK 12 0 Q9NR30 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 AEPS(0.001)EVDMNS(0.999)PK;AEPS(0.001)EVDMNS(0.999)PK;AEPSEVDMNS(1)PK;AEPS(0.033)EVDMNS(0.967)PK;AEPS(0.003)EVDMNS(0.997)PK;AEPSEVDMNS(1)PK 127.03 0.00024631 143894600.0 476036.0 369251.0 374113.0 416112.0 396158.0 338565.0 411968.0 371049.0 394584.0 437557.0 True False 627405.5458360933 488604.16465313814 369152.0171789081 320183.8072663139 341158.29988484073 317394.4770286372 448632.35391223524 313711.90290778363 415440.9046807987 422238.2626119851 1.485904053211412 1.1571764283762693 0.8742741950843511 0.7583012616754395 0.8079758044058347 0.7516952041845296 1.062509946722912 0.7429736494441492 0.9839016059578836 1.0 18.687697793954086 -4.937847270216304 2.124786070769392 0.857938538221046 1.552939708652592 0.7625268421344493 0.10783879348449082 0.21225179929165353 1.410284374269525 0.02827489840782514 0.25289246969006113 1.1538589678959433e-05 4.937847270216304 0.695001170431546 AEPSEVDMNS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AEPSEVDMNSPK 12 0 Q9NR30 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 AEPSEVDMNS(1)PK;AEPSEVDMNS(1)PK;AEPSEVDMNS(1)PK 118.76 0.00050178 80823000.0 115975.0 152537.0 101789.0 126068.0 135258.0 107332.0 143272.0 173636.0 114972.0 86797.0 True False 135607.27688933807 167679.86527808625 104216.03579693238 119004.81867797057 108755.16585767701 101703.32097281277 129700.2389605458 169078.23898254932 116653.24799434541 102532.609015326 1.322577062962167 1.635380849940358 1.0164184526052074 1.1606533747735064 1.0606885643709787 0.9919119580543466 1.26496575290656 1.649019181373571 1.1377185181829201 1.0 16.64572328546447 -5.2608943195702125 24.99929201081807 1.1775487952534807 1.478978951870718 0.29313111659082036 0.19655152680751206 65.07788243666144 2984620.503201682 0.05402126953085314 0.12644374369070696 5.4841039787487496e-06 5.2608943195702125 0.30143015661723727 AEPSEVDMNS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 9 AEPSEVDMNSPK 12 0 Q9NR30 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 AEPSEVDMNS(1)PK;AEPSEVDMNS(1)PK;AEPSEVDMNS(1)PK;AEPSEVDMNS(1)PK;AEPSEVDMNS(1)PK;AEPSEVDMNS(1)PK;AEPSEVDMNS(1)PK;AEPSEVDMNS(1)PK;AEPSEVDMNS(1)PK 150.26 0.00016057 240303700.0 554426.0 758582.0 692436.0 835670.0 769557.0 641828.0 671241.0 662155.0 643145.0 669964.0 True False 546519.7835707237 756825.5499861394 635506.5849602576 897127.9595134004 724293.1702672738 614378.5126141435 705994.5745725619 692921.138615672 570707.2374829066 785766.3847290854 0.6955245149092901 0.9631686525341446 0.8087729346927536 1.1417235159820562 0.9217665509030318 0.7818844437153767 0.8984789732586651 0.8818411579856215 0.7263065060739059 1.0 19.583740924720075 -6.655686644133894 19.023307094954784 0.8526845470350902 0.9170476447017366 0.03142682017695764 0.12611881601145467 7.01491239848967 1230.12459063533 0.040990884826186486 0.040990684080687026 2.2095984463493823e-07 6.655686644133894 0.06436309766664638 AEPYVAS(ph)EYK ddPTM_PC-9_AZD4547_30min_R2 2 AEPYVASEYK 10 0 Q6ZSL5;A0A088AWN3;A0A0A0MSY4;Q9BZ29-3;Q9BZ29-5;Q9BZ29;Q9BZ29-4;A0A0A0MT38;Q9BZ29-6 Q6ZSL5 DOCK9 Dedicator of cytokinesis protein 9 1 AEPYVAS(1)EYK;AEPYVAS(1)EYK 142.89 0.00011584 41632000.0 66130.0 79005.0 77545.0 62111.0 54377.0 72186.0 77251.0 67288.0 69490.0 62901.0 True False 87157.96441055027 104541.8212230193 76516.70263299705 47792.26855538416 46827.69216534301 67672.19800862204 84126.1893449832 56890.18572441642 73163.09953335334 60698.855135574326 1.4359078802372471 1.7223030152631253 1.2605954834253903 0.7873668860580224 0.7714757067616961 1.1148842570007682 1.385960067238214 0.9372530272168885 1.2053456258761293 1.0 15.889381685061611 -5.490520178871461 5.376765670955318 1.0323620092760042 1.566512697608916 0.5838269409455303 0.18502057771294295 0.13626015749985962 10.788120394314507 0.052768985274496354 0.10708062457924987 3.2320630267250194e-06 5.490520178871461 0.5341506883329119 AEPYVAS(ph)EYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AEPYVASEYK 10 0 Q6ZSL5;A0A088AWN3;A0A0A0MSY4;Q9BZ29-3;Q9BZ29-5;Q9BZ29;Q9BZ29-4;A0A0A0MT38;Q9BZ29-6 Q6ZSL5 DOCK9 Dedicator of cytokinesis protein 9 1 AEPYVAS(1)EYK;AEPYVAS(1)EYK;AEPYVAS(1)EYK;AEPYVAS(1)EYK 153.34 0.00015537 41165600.0 154724.0 172511.0 130776.0 132597.0 140080.0 109342.0 132765.0 113799.0 97492.0 89338.0 True False 180915.71726170243 189636.75199451894 133894.19581074174 125168.01997527423 112632.32957269406 103607.91303440994 120188.53806463856 110811.89683000738 98917.63606325666 105534.27220078128 1.7142840282018175 1.796921019493372 1.2687271444484411 1.1860414381513837 1.067258315463706 0.9817466011163993 1.138857885294146 1.0500086324486637 0.9373034370774234 1.0 16.687352063935407 -5.4347121204342494 1.7053832796083792 1.0422337418578567 1.802149092235817 0.9323230112296201 0.07468689931080816 0.09121830735363945 0.4921789924977163 0.02186835438144252 0.0732236531211212 3.6752584059545743e-06 5.4347121204342494 0.7599153503779603 AEPYVAS(ph)EYK ddPTM_PC-9_Lapatinib_30min_R1 2 AEPYVASEYK 10 0 Q6ZSL5;A0A088AWN3;A0A0A0MSY4;Q9BZ29-3;Q9BZ29-5;Q9BZ29;Q9BZ29-4;A0A0A0MT38;Q9BZ29-6 Q6ZSL5 DOCK9 Dedicator of cytokinesis protein 9 1 AEPYVAS(1)EYK;AEPYVAS(1)EYK 164.48 0.00011673 44429000.0 62832.0 85318.0 61228.0 71332.0 62906.0 69357.0 75513.0 66312.0 65445.0 44999.0 True False 61936.00415802239 85120.45141292238 56194.07018691485 76577.99323657637 59205.99275795449 66390.76278906374 79422.69365205325 69393.0976038579 58073.894933597905 52777.01719260151 1.173541201314894 1.612831795747163 1.064745095044749 1.450972360888015 1.1218139240778127 1.2579483707232066 1.5048727244704354 1.3148355343883604 1.1003633403848168 1.0 15.687622195483732 -8.38238530008633 3.3449840940013593 1.0066497526049287 1.317585424440684 0.3000331319441598 0.16345839036774168 0.2773525351809826 5.49964727084084 0.14760314170238614 0.039539589764648164 4.1458606437629215e-09 8.38238530008633 0.3109356718357552 AERT(ph)PVSHPQR ddPTM_PC-9_Lapatinib_30min_R1 1 AERTPVSHPQR 11 1 Q9BY89;A0A1B0GVJ7;Q9BY89-2 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 AERT(0.996)PVS(0.004)HPQR 71.031 0.022161 2692300.0 1949.9 823.45 2077.5 2135.0 2006.7 842.74 2488.3 902.14 2703.8 2093.4 True False 1922.0940684321333 821.5433521176175 1906.6959693819103 2292.015022151215 1888.6698513239946 806.697974722891 2617.1319986545946 944.0567178239874 2399.2695717237675 2455.2414007198377 0.782853395950641 0.3346079745465167 0.7765818745248013 0.9335192138252608 0.7692399821745701 0.3285615721885351 1.0659367335070569 0.3845066792809884 0.9772031259412374 1.0 11.261649162766162 -8.431684191345376 12.271281122531827 0.9999808731220191 0.6778864329317893 0.21929371266987874 0.23895105587096227 1.1399750228788381 148.2193971732028 0.22053010006853374 0.056945373408693795 3.700972078713849e-09 8.431684191345376 -0.3220944401902298 AES(ph)GDSLGSEDRDLLYSIDAYR ddPTM_PC-9_Lapatinib_30min_R1 1 AESGDSLGSEDRDLLYSIDAYR 22 1 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 AES(0.88)GDS(0.101)LGS(0.019)EDRDLLYSIDAYR 50.14 0.017929 5224800.0 5241.9 3059.0 6442.9 5196.5 5039.6 5279.8 3033.5 4682.8 8239.7 2580.0 True False 5167.1495447532725 3051.9170734444006 5913.189632313217 5578.66794501583 4743.180636234813 5053.995261814939 3190.559786970504 4900.379983401876 7311.658218112408 3025.949562366092 1.7076125818544392 1.0085816073741836 1.9541600117384292 1.8436090324829082 1.5675015523146925 1.670217945689435 1.0543995268961779 1.6194519711591306 2.416318602612522 1.0 11.563172225048609 -8.015461743316955 24.980647974654328 1.8114012522874543 1.540577438519388 0.011768256729782767 0.430348291383536 2106.163122091648 3402787.365049065 0.26319681420600016 0.10639637397744732 9.650243163472465e-09 8.015461743316955 -0.2708238137680663 AES(ph)GPDLR ddPTM_PC-9_AZD4547_30min_R2 1 AESGPDLR 8 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 AES(1)GPDLR 96.665 0.0060501999999999995 275110000.0 187780.0 203260.0 325440.0 440730.0 396650.0 305100.0 296190.0 364050.0 287340.0 375640.0 True False 247490.13393336095 268959.82003406016 321124.45296128135 339126.507710622 341581.9941773782 286022.0487688833 322550.33620393975 307794.4375367646 302528.2057837637 362488.9579359178 0.6827522011777066 0.7419807256076693 0.8858875447953672 0.9355498982415186 0.9423238603526356 0.7890503765895329 0.8898211356301823 0.8491139682968708 0.8345859898917137 1.0 18.467577523154112 -5.16020881741976 3.2899035084989054 0.8856877793483047 0.6928813053945662 0.6167897077014475 0.05692089491800077 0.16847171406137504 3.376170611758591 0.01502636709591372 0.05008305100978304 6.914984047945823e-06 5.16020881741976 -0.1928064739537385 AES(ph)GPDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AESGPDLR 8 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 AES(1)GPDLR;AES(1)GPDLR 89.029 0.010532 291740000.0 191781.0 195696.0 261970.0 264204.0 302079.0 269343.0 284833.0 232821.0 240553.0 199906.0 True False 224245.73545259057 215123.40557019258 268216.35832675715 249401.50644092532 242888.7884422459 255218.17892874734 257851.55622765867 226709.6954442404 244070.63254343468 236147.37534497443 0.9496007953719688 0.9109709784236683 1.1358007173907183 1.0561265230095769 1.0285474826363126 1.0807580586314518 1.0919094732726875 0.9600347880769496 1.0335521713374354 1.0 17.849327975210777 -5.2390817807832 24.918131352960838 1.0491987165267727 0.9302858592463933 0.5015425877998798 0.04707042356444258 632.9349805336534 705420.232837527 0.012185451841017735 0.03218564468966213 5.766578643327006e-06 5.2390817807832 -0.11891285728037937 AES(ph)GPDLR ddPTM_PC-9_Lapatinib_30min_R1 3 AESGPDLR 8 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 AES(1)GPDLR;AES(1)GPDLR;AES(1)GPDLR 93.598 0.007104899999999999 452540500.0 353932.0 329881.0 388578.0 282730.0 277642.0 279162.0 248550.0 254395.0 306906.0 218135.0 True False 348884.86477682093 329117.18081232795 356630.6167944577 303522.9073596311 261311.6434251738 267222.8920184062 261418.70283550958 266215.12041460705 272339.01441654516 255839.34410338334 1.3636873014958888 1.2864212967937152 1.393963145286775 1.1863808845483088 1.021389592523264 1.0444949073603895 1.0218080559566776 1.0405558275158449 1.0644923100900947 1.0 17.964878619727884 -6.018466562067433 3.117522610141877 1.0348191637919275 1.3412703339164291 0.9514564148837386 0.031960151596296255 0.04774902496478731 0.9492169342412973 0.009331607293451455 0.013560558648736792 9.583705019424313e-07 6.018466562067433 0.3064511701245016 AES(ph)LDDQMLSR ddPTM_PC-9_AZD4547_30min_R2 1 AESLDDQMLSR 11 0 Q6ZV73-2;Q6ZV73;F8VY01 Q6ZV73-2 FGD6 FYVE, RhoGEF and PH domain-containing protein 6 1 AES(1)LDDQMLSR 93.649 0.018559 0.0 4397.0 5113.0 6981.7 9885.5 7719.8 8876.9 4811.7 8087.0 6708.8 6018.2 True False 5795.154536718433 6765.677259835435 6889.1180962382605 7606.550704452509 6648.0390234476945 8321.826039713216 5239.931978501972 6837.339970772729 7063.41347171335 5807.504649797513 0.9978734217493032 1.1649886944251229 1.1862440947814756 1.3097795289268899 1.1447324495348425 1.4329435000974764 0.9022690973970497 1.177328367875026 1.2162561887849073 1.0 12.503702688795116 -10.558165360132495 7.2532506198667175 0.9999999824931944 1.1739862283457108 0.11846762480001205 0.13900702245108798 3.840013717678005e-08 4.995626175171396e-09 0.1314409622709163 0.031879112614505566 2.7658883169411785e-11 10.558165360132495 0.17398624585251632 AES(ph)LDDQMLSR ddPTM_PC-9_Lapatinib_30min_R1 3 AESLDDQMLSR 11 0 Q6ZV73-2;Q6ZV73;F8VY01 Q6ZV73-2 FGD6 FYVE, RhoGEF and PH domain-containing protein 6 1 AES(1)LDDQMLSR;AES(1)LDDQMLSR;AES(1)LDDQMLSR 165.51 0.0016385999999999998 12900100.0 74172.0 48001.7 75141.0 59258.0 71809.8 65888.4 61088.6 60563.4 80511.0 75061.0 True False 73114.29367852093 47890.55501286563 68963.19703264783 63616.03099889306 67586.08874749874 63070.50672536217 64251.46879918454 63377.396661561725 71443.00336158449 88035.19383750451 0.8305120996663606 0.5439932931966059 0.7833594046483296 0.7226204455949244 0.767716702847832 0.716423784353537 0.72983844299565 0.7199097758396922 0.8115277566543908 1.0 16.425792764941733 -8.67315995808443 2.0818049388209423 0.9998887618107074 0.7229936965512016 0.5812410276335052 0.07036537905352473 0.38268946271868093 3.2941701596063013 0.06332556584491536 0.017485421481971946 2.122462578755198e-09 8.67315995808443 -0.2768950652595058 AES(ph)LPLSSNLQSK ddPTM_PC-9_AZD4547_30min_R2 4 AESLPLSSNLQSK 13 0 Q8N1W1-5;Q8N1W1-4;Q8N1W1-3;Q8N1W1;Q8N1W1-6;Q8N1W1-2 Q8N1W1-5 ARHGEF28 Rho guanine nucleotide exchange factor 28 1 AES(0.425)LPLS(0.288)S(0.288)NLQSK;AES(1)LPLSSNLQSK;AES(0.602)LPLS(0.381)S(0.017)NLQSK;AES(0.986)LPLS(0.01)S(0.005)NLQSK 168.93 0.00022279 40157400.0 119920.0 109105.0 151566.0 212508.0 170151.0 157584.0 121701.0 159159.0 141317.0 148683.0 True False 158052.06550904576 144371.05758543825 149556.13580853486 163517.56381587122 146528.47067004925 147730.24756865177 132532.15323392325 134564.63365997458 148786.72811562647 143477.65342558283 1.1015796657911066 1.0062267826279916 1.0423653596070606 1.1396726940525441 1.0212633617265616 1.029639417996717 0.9237128575054606 0.9378786901457714 1.0370027984378576 1.0 17.13046652978663 -6.887148447833202 2.443349039158767 0.9705880428448167 1.064378233174914 0.43701150402778477 0.04644185880500303 0.27111079818712014 3.2930431525793677 0.018693317652545727 0.0159940184458972 1.2967359530202123e-07 6.887148447833202 0.09379019033009739 AES(ph)LPLSSNLQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AESLPLSSNLQSK 13 0 Q8N1W1-5;Q8N1W1-4;Q8N1W1-3;Q8N1W1;Q8N1W1-6;Q8N1W1-2 Q8N1W1-5 ARHGEF28 Rho guanine nucleotide exchange factor 28 1 AES(0.99)LPLS(0.005)S(0.005)NLQSK;AES(0.995)LPLS(0.004)S(0.001)NLQSK;AES(0.996)LPLS(0.004)SNLQSK 191.19 1.2457000000000001e-05 20006800.0 108437.0 112993.0 101195.0 127057.0 128078.0 142181.0 157235.0 156105.0 140493.0 121708.0 True False 126793.24237162493 124210.19829527779 103607.87258417447 119938.40821435156 102982.03531561613 134724.77806465438 142340.56251718005 152007.40915691952 142547.44433835728 143772.69696000213 0.8819007019594206 0.8639345364011175 0.7206366352924325 0.834222427139408 0.7162836720261703 0.9370678919804579 0.9900388983923666 1.0572759110111727 0.991477849080165 1.0 17.133430202367506 -6.961104304730894 4.615012414484512 1.0093548794822693 0.804052915234019 0.7693467556785487 0.05357851655369634 0.09729408891465982 4.758726490437878 0.020304813076161103 0.0173985083761294 1.0936936617526101e-07 6.961104304730894 -0.2053019642482503 AES(ph)LPLSSNLQSK ddPTM_PC-9_Lapatinib_30min_R1 3 AESLPLSSNLQSK 13 0 Q8N1W1-5;Q8N1W1-4;Q8N1W1-3;Q8N1W1;Q8N1W1-6;Q8N1W1-2 Q8N1W1-5 ARHGEF28 Rho guanine nucleotide exchange factor 28 1 AES(0.994)LPLS(0.002)S(0.002)NLQS(0.002)K;AES(0.973)LPLS(0.013)S(0.013)NLQSK;AES(0.976)LPLS(0.019)S(0.005)NLQSK 105.46 0.0012265000000000002 25721900.0 172154.0 147235.0 190292.0 134590.0 201382.0 213334.0 218898.0 228881.0 263478.0 193097.0 True False 169699.0523908233 146894.08640359173 174646.92630836257 144488.1975790782 189537.10669224523 204210.20212584353 230231.46736386025 239515.6468311698 233802.33309365885 226473.55916442102 0.7493106613281105 0.6486147298852925 0.7711581296850992 0.6379914640462686 0.8369061156257993 0.9016955572177228 1.016593143205344 1.057587683590384 1.0323603954310494 1.0 17.788983099591057 -6.798843601218653 1.5091423823287087 1.0352173646436693 0.7014504828402676 0.9093379605673686 0.04556352523856594 0.09838654257572636 0.46562950473741344 0.019457443118514578 0.017100269279374462 1.5891189214593533e-07 6.798843601218653 -0.33376688180340175 AES(ph)PAEKVPEESVLPLVQK ddPTM_PC-9_AZD4547_30min_R2 4 AESPAEKVPEESVLPLVQK 19 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 AES(0.999)PAEKVPEES(0.001)VLPLVQK;AES(1)PAEKVPEESVLPLVQK;AES(1)PAEKVPEESVLPLVQK;AES(1)PAEKVPEESVLPLVQK 90.706 0.00046298 43069100.0 101734.59999999999 120799.0 116847.0 110675.9 117726.2 140850.0 130300.4 142647.0 130239.9 122063.2 True False 134084.0865888642 159844.9143968045 115297.53243352653 85161.28118060957 101381.94923213129 132042.6272340123 141896.8831746783 120604.18385196239 137124.11522397446 117789.8045211464 1.1383335521606415 1.3570352293785162 0.9788413598464505 0.7229936540502608 0.8607022453622506 1.121002176468568 1.2046618444740185 1.0238932337332365 1.1641424805943796 1.0 16.845855144306867 -5.274007113255338 24.524336701385224 1.005784422996177 1.2476843917009335 0.30769703957754424 0.14280288531999655 683.5280787666859 1333819.2373360596 0.04174775895029482 0.08790596365813996 5.320995440031283e-06 5.274007113255338 0.2418999687047565 AES(ph)PAEKVPEESVLPLVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 AESPAEKVPEESVLPLVQK 19 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 AES(0.989)PAEKVPEES(0.011)VLPLVQK;AES(1)PAEKVPEESVLPLVQK;AES(0.988)PAEKVPEES(0.012)VLPLVQK;AES(1)PAEKVPEESVLPLVQK;AES(1)PAEKVPEESVLPLVQK 128.4 1.6301e-05 56287700.0 278109.5 448731.0 334349.0 316065.0 344952.7 240852.5 337333.3 208005.1 239305.0 258467.0 True False 325187.9454369946 493278.0481201359 342321.1481856429 298356.902746556 277361.6946986765 228221.7709034058 305378.6477424022 202545.1865246211 242804.3829044191 305325.02107635397 1.0650550167510622 1.6155834408238023 1.1211696538294422 0.9771780304632962 0.9084145600675009 0.7474715635779269 1.0001756379672364 0.6633756572278094 0.7952325100919257 1.0 18.219986296224036 -5.72605632342418 2.1180208857140372 0.8424848174004881 1.3449797168741442 0.5780589316697156 0.16234717801135437 0.1965323711436508 1.794929238114093 0.04641152399264991 0.09273790862270265 1.8790731049921333e-06 5.72605632342418 0.5024948994736561 AES(ph)PAEKVPEESVLPLVQK ddPTM_PC-9_Lapatinib_30min_R1 3 AESPAEKVPEESVLPLVQK 19 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 AES(0.995)PAEKVPEES(0.005)VLPLVQK;AES(1)PAEKVPEESVLPLVQK;AES(0.999)PAEKVPEES(0.001)VLPLVQK 81.346 0.0010343 44366000.0 141565.2 175897.0 142166.4 151788.0 182401.0 165744.0 177936.0 173065.0 150636.9 145740.0 True False 139546.4542881216 175489.72130357957 130478.02737017398 162950.99586992458 171672.53179416334 158655.51548813505 187148.6554324653 181106.23170484425 133670.58604512023 170930.9648136566 0.816390724993863 1.0266701618100194 0.7633375703016531 0.9533146674013597 1.0043384004841671 0.9281847537752808 1.094878599886736 1.059528517271756 0.7820150444411494 1.0 17.383054244982375 -5.984751554364088 24.762596871214043 0.9839582387452088 0.8802097912919139 0.1872653813200229 0.10087677996238219 367.7540653649015 597205.9011500425 0.027679605915526734 0.04103911848073517 1.035734506991612e-06 5.984751554364088 -0.10374844745329492 AES(ph)PDLR ddPTM_PC-9_Lapatinib_30min_R1 1 AESPDLR 7 0 Q6UN15;Q6UN15-5;A0A0B4J203;Q6UN15-4 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 AES(1)PDLR 102.62 0.010818000000000001 138020000.0 233980.0 220680.0 238770.0 191160.0 209290.0 219550.0 198580.0 184410.0 204720.0 161060.0 True False 230643.40229332304 220169.02901853865 219139.25227885428 205218.544091066 196979.97367997133 210160.35829604717 208861.50074059766 192978.36182180347 181662.27780282946 188899.0064010396 1.2209879061177196 1.1655383117850373 1.1600868445735153 1.086392924986484 1.0427793000762298 1.1125540695003389 1.10567813309286 1.0215954307991606 0.9616899594334217 1.0 17.527255587682085 -1.5228787452811914 0.1914073223579599 0.9725171292846463 2.116283488330365 0.7900693157782044 0.035480108620760016 26.47000340607754 0.310890992683228 0.07805918117814208 8.961135496959416 0.029999999999941022 1.5228787452811914 1.1437663590457188 AES(ph)PDLRR ddPTM_PC-9_AZD4547_30min_R2 1 AESPDLRR 8 1 Q6UN15;Q6UN15-5;A0A0B4J203;Q6UN15-4 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 AES(1)PDLRR 55.083999999999996 0.041641000000000004 8093100.0 24045.0 22926.0 35508.0 56564.0 46420.0 24901.0 21032.0 26323.0 26930.0 32770.0 True False 31690.809832930354 30336.38115763486 35037.14071948495 43524.04370508843 39975.38426752533 23343.93653357579 22903.807255617245 22255.385192364356 28353.464821315363 31622.732274411712 1.0021528044423198 0.9593219489823233 1.1079732268370779 1.376353040192765 1.2641344182606373 0.7382011247796286 0.7242829954371276 0.7037780606444571 0.8966165407616674 1.0 14.948674404691888 -6.768476658313767 24.999803856243645 0.7885435242047594 1.142969704387493 0.5802220859907756 0.13934561891972666 123.16305523924501 437531.69396933384 0.05314460762279736 0.04785668843365823 1.704210911746628e-07 6.768476658313767 0.35442618018273353 AES(ph)PEEVACR ddPTM_PC-9_AZD4547_30min_R2 2 AESPEEVACR 10 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 AES(1)PEEVACR;AES(1)PEEVACR 151.79 0.00016698 158265000.0 112932.0 101388.0 146615.0 170519.0 158927.0 145462.0 110849.0 163953.0 122546.0 117227.0 True False 148842.02686847525 134159.6882495979 144670.78930346094 131208.4790422881 136862.7293297068 136366.23814493368 120714.34625703297 138617.8311151354 129023.53137738268 113122.91841112163 1.3157548351744248 1.1859638182425822 1.2788813384188442 1.1598753010016791 1.209858543715322 1.2054695906035509 1.0671077793301078 1.2253735411188547 1.1405604910976004 1.0 16.787531719666184 -14.522878744740629 0.05172376523689178 0.2080254417440959 1.578582033847801 0.6367894785551917 0.053544103868373605 338.2104563762724 1.2862723417244362 36.24562051155148 7.670513315359116 3.000000003728177e-15 14.522878744740629 1.370556592103705 AES(ph)PEEVACR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AESPEEVACR 10 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 AES(1)PEEVACR;AES(1)PEEVACR 113.38 0.0013155999999999999 90611000.0 88143.0 90089.0 98106.0 108594.0 128795.0 107718.0 110165.0 100772.0 100079.0 81490.0 True False 103063.86899639544 99032.4405425405 100445.21910907712 102509.83024649818 103558.54431264345 102069.07845329866 99729.37367446908 98126.84177675976 101542.4660441334 96263.49192551497 1.0706433657750785 1.0287642652644269 1.0434404268941107 1.0648879257965875 1.0757821292497172 1.0603093281955305 1.036004114120812 1.019356765622907 1.0548387972742885 1.0 16.55470113707466 -8.863027805561913 0.540650643221958 0.9993030266040552 1.05558269594722 0.46614108922645336 0.016915509991455312 1.425704399323166 0.8375179977781427 0.02372172546139642 0.008832727855056592 1.3707939987185974e-09 8.863027805561913 0.05627966934316486 AES(ph)PEEVACR ddPTM_PC-9_Lapatinib_30min_R1 1 AESPEEVACR 10 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 AES(1)PEEVACR 123.01 0.00049114 40282000.0 40215.0 49467.0 69641.0 39600.0 53178.0 59956.0 45374.0 53597.0 69437.0 46211.0 True False 39641.52672547223 49352.462200743445 63915.38580203404 42512.316101727454 50050.17459197059 57391.82164426233 47723.24370331292 56087.31228546814 61616.27385597425 54198.509777712985 0.7314135921459091 0.9105870697027487 1.179283084796489 0.7843816421537291 0.9234603459992505 1.0589188130752345 0.8805268613296308 1.0348497129441712 1.1368628788629818 1.0 15.725965563861807 -4.848155638782398 3.943824389397728 0.9913848347508685 0.7239919815154094 0.34666551727739714 0.11123242451906001 0.2549431080643837 6.651567619506234 0.027881251251893835 0.16678134706290995 1.4185490629733622e-05 4.848155638782398 -0.267392853235459 AES(ph)PEEVACRK ddPTM_PC-9_AZD4547_30min_R2 2 AESPEEVACRK 11 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 AES(1)PEEVACRK;AES(1)PEEVACRK 92.11200000000001 0.011495 7015600.0 27111.0 22180.0 31971.0 39368.0 40301.0 31823.0 28629.0 35114.0 26195.0 33166.0 True False 35731.734056168614 29349.251246459993 31547.043650519707 30292.31582953686 34705.90179589696 29833.102779325403 31176.925538278152 29687.9381394477 27579.614221847598 32004.868434944747 1.1164468346057834 0.9170245866224153 0.9856951518061808 0.9464908718844154 1.0843944528765215 0.9321426469840418 0.9741307201949752 0.927606942043627 0.8617318417636298 1.0 14.966003757559601 -7.303642742584636 1.7264457949111378 0.9251676247774406 0.9979801208621435 0.17791431738047614 0.06650371465212217 0.6518398369889269 3.783914872491472 0.035859708483175386 0.021303631251910683 4.9700099410749944e-08 7.303642742584636 0.07281249608470286 AES(ph)PEEVACRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AESPEEVACRK 11 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 AES(1)PEEVACRK 68.536 0.040889 0.0 13793.0 10055.0 11874.0 12632.0 11985.0 16955.0 16078.0 10428.0 10625.0 11186.0 True False 16127.88247583223 11053.193948820013 12157.12119239576 11924.269993496562 9636.625285042368 16065.849952428354 14554.975445360267 10154.276049379305 10780.37052447484 13213.933251672717 1.2205209583445296 0.8364802317599734 0.9200229001351147 0.9024012583071812 0.7292775815877905 1.2158264800069745 1.1014869810635521 0.7684521978415398 0.8158335840776387 1.0 13.689772341824378 -7.775153768364978 24.996387990821866 0.8441071941314519 0.9762330013824546 0.11328689799968317 0.15897308727748086 545.7876043056519 994759.3289856976 0.08821495544199962 0.04273550715122538 1.6782097180225892e-08 7.775153768364978 0.13212580725100276 AES(ph)PESSAIESTQST(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 1 AESPESSAIESTQSTPQK 18 0 Q9NTI5-2;Q9NTI5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 2 AES(1)PESSAIESTQS(0.124)T(0.876)PQK 220.89 1.8852999999999997e-80 0.0 13809.0 16401.0 14843.0 17833.0 16102.0 19195.0 19539.0 22427.0 19633.0 19962.0 True False 18199.974754956747 21702.302510964386 14646.17212175609 13721.8773671035 13866.515240751669 17994.733615597237 21277.933147941483 18961.42247119081 20670.76029843612 19263.13645595991 0.9448084841513841 1.126623515364748 0.760321256885695 0.7123386888980909 0.7198472207500479 0.9341538776272212 1.104593387301589 0.9843372347250465 1.0730734501982255 1.0 14.233555003865787 -7.003906691019785 24.62572149289545 1.0363640702515065 0.852255094921125 0.35942294366583794 0.1180831875799778 174.33864835379478 1098945.62743172 0.047442034902212236 0.04089933803782065 9.910448498565928e-08 7.003906691019785 -0.1841089753303815 AES(ph)PESSAIESTQST(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 1 AESPESSAIESTQSTPQK 18 0 Q9NTI5-2;Q9NTI5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 2 AES(1)PESSAIESTQS(0.146)T(0.854)PQK 277.64 2.7175999999999994e-90 6363100.0 33381.0 43498.0 45717.0 44861.0 49458.0 48333.0 46547.0 48412.0 48999.0 45454.0 True False 32904.98081867433 43397.283053509134 41958.32473272337 48160.22759190897 46548.9776781692 46265.91025972599 48956.97590377981 50661.398256695036 43480.21663765551 53310.663336352074 0.6172307519617133 0.8140450772428657 0.7870531354674095 0.9033882637710294 0.8731644808934099 0.8678547098133306 0.9183336473398648 0.9503051563447621 0.8156007432007835 1.0 15.702136512980504 -3.937623358358489 0.663409528332144 0.9078431187172588 9.73892231886742e-14 0.7292269576594397 0.05238218025220358 4.452658489810805 0.6491313722731544 0.020986092578790406 3.946870219004522 0.00011544540233944433 3.937623358358489 -0.9078431187171614 AES(ph)PESSAIESTQSTPQK ddPTM_PC-9_AZD4547_30min_R2 4 AESPESSAIESTQSTPQK 18 0 Q9NTI5-2;Q9NTI5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 AES(0.997)PES(0.001)S(0.002)AIESTQSTPQK;AES(0.981)PES(0.018)S(0.002)AIESTQSTPQK;AES(0.997)PES(0.003)SAIESTQSTPQK;AES(0.998)PES(0.002)SAIESTQSTPQK 323.2 1.1285999999999997e-176 202259300.0 165550.0 183609.0 228402.0 307938.0 236186.0 223021.0 179037.0 240578.0 174389.0 197390.0 True False 218191.45634608564 242957.01858030958 225373.24024478433 236947.65169467402 203395.6507671206 209075.46161417657 194970.94615937356 203402.19803246757 183606.84651780044 190479.43618083975 1.1454856267998206 1.2755026130466283 1.1831893497984562 1.2439539744842467 1.067808971116537 1.0976274699578694 1.0235800255848595 1.067843343673902 0.9639195190786132 1.0 17.539275729786475 -6.578214981473142 1.177794198252499 1.016763411085328 1.2200015822339145 0.7634712163456745 0.047768689303125694 0.2118998823531188 0.6205669835205115 0.02120362550258177 0.022818296778603284 2.641101053970042e-07 6.578214981473142 0.20323817114858644 AES(ph)PESSAIESTQSTPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 AESPESSAIESTQSTPQK 18 0 Q9NTI5-2;Q9NTI5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 AES(0.561)PES(0.098)S(0.341)AIESTQSTPQK;AES(0.491)PES(0.471)S(0.038)AIESTQSTPQK;AES(0.643)PES(0.357)SAIESTQSTPQK;AES(0.998)PES(0.002)SAIESTQSTPQK;AES(1)PESSAIESTQSTPQK 311.43 8.303499999999997e-139 144565000.0 205122.1 222167.0 182633.0 243462.0 263413.0 222919.0 244955.0 190454.4 202958.9 187163.2 True False 239845.2201838546 244222.2715094477 186987.66335950987 229821.61345445339 211799.1135760418 211228.73521352836 221751.08907937715 185455.1738031175 205926.7899519846 221094.4065769237 1.0848090817729803 1.10460628692783 0.8457367432063582 1.0394727619420498 0.9579578102187408 0.955378014685492 1.0029701452543305 0.8388053622631719 0.9313975560948352 1.0 17.754303001599958 -5.236228489006727 24.761324879658716 0.9467764012227086 1.094707744168668 0.486707115030135 0.06089446042629912 562.9337715518512 552893.2489619418 0.015225089475762971 0.04024495632193697 5.804589487915755e-06 5.236228489006727 0.14793134294595933 AES(ph)PESSAIESTQSTPQK ddPTM_PC-9_Lapatinib_30min_R1 6 AESPESSAIESTQSTPQK 18 0 Q9NTI5-2;Q9NTI5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 AES(0.909)PES(0.083)S(0.008)AIESTQSTPQK;AES(0.999)PES(0.001)SAIESTQSTPQK;AES(0.993)PES(0.007)SAIESTQSTPQK;AES(0.668)PES(0.332)SAIESTQSTPQK;AES(0.873)PES(0.126)SAIESTQSTPQK;AES(0.997)PES(0.003)SAIESTQSTPQK 342.02 2.1047999999999986e-222 215293200.0 393267.0 346549.0 367273.0 271578.7 263943.0 353001.0 323740.0 329932.0 337406.0 209064.7 True False 387658.9404636646 345746.587082407 337077.23165477853 291551.50355798553 248418.3916719035 337903.9701155219 340501.67312801466 345261.84519598336 299403.78323730646 245201.25483379752 1.5809826940992935 1.4100522744745378 1.3746961934728126 1.189029410781789 1.013120393043203 1.378067866514632 1.3886620333929929 1.4080753600955631 1.221053226013254 1.0 17.90360683657262 -5.054690930007553 1.590645802913536 1.2533952674385238 1.6028690377860024 0.38201532895272305 0.13907741009342373 0.7598998607716861 2.679498411876265 0.042155070956456805 0.3524763931779768 8.81676103372254e-06 5.054690930007553 0.3494737703474786 AES(ph)PMSR ddPTM_PC-9_AZD4547_30min_R2 1 AESPMSR 7 0 Q6ZUT6 Q6ZUT6 C15orf52 Uncharacterized protein C15orf52 1 AES(1)PMSR 83.647 0.020712 30034000.0 12211.0 10381.0 18371.0 28666.0 25140.0 16132.0 14742.0 19742.0 12610.0 17469.0 True False 16093.843995421612 13736.45523848066 18127.388536601833 22057.49658528507 21649.744947987634 15123.263489805408 16054.009440961836 16691.32752602884 13276.538856174782 16857.415627149774 0.9547041107239245 0.8148612778080502 1.0753361569496276 1.30847438736459 1.2842861223116286 0.8971282327196453 0.9523410821707445 0.9901474754615742 0.7875785440558399 1.0 14.041095756417741 -6.865334872293114 19.95078258090919 0.9264792711772853 1.0847741750977484 0.2380819585099555 0.14491684938159224 5.024138906214104 946.3966640772462 0.057962412491714944 0.051118148894184506 1.363531350362151e-07 6.865334872293114 0.15829490392046308 AES(ph)PMSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AESPMSR 7 0 Q6ZUT6 Q6ZUT6 C15orf52 Uncharacterized protein C15orf52 1 AES(0.998)PMS(0.002)R;AES(1)PMSR;AES(0.996)PMS(0.004)R 78.264 0.028586 70992000.0 63082.0 72697.0 88510.0 81653.0 119426.0 91363.0 79889.0 87378.0 83456.0 61434.0 True False 73760.53667370774 79913.87772226433 90620.41407604427 77078.24713259767 96025.33260671406 86571.76344463069 72321.33557372731 85084.42008464379 84676.38611675968 72571.4978887236 1.0163843770567798 1.1011744286276004 1.2487053004610114 1.0621008160915242 1.3231824531712577 1.1929168607953247 0.9965528847788166 1.172421991552478 1.1667994816173826 1.0 16.147115427379976 -10.067386132984103 8.463885788275013 1.000006485212932 1.1452285446451342 0.1625521142775409 0.0966489796741563 0.0 0.0 0.09399094895099377 0.022796153551587345 8.562761880549234e-11 10.067386132984103 0.14522205943220223 AES(ph)PMSR ddPTM_PC-9_Lapatinib_30min_R1 3 AESPMSR 7 0 Q6ZUT6 Q6ZUT6 C15orf52 Uncharacterized protein C15orf52 1 AES(0.998)PMS(0.002)R;AES(0.998)PMS(0.002)R;AES(0.956)PMS(0.044)R 95.35799999999999 0.017672999999999998 68159000.0 71139.0 59654.0 91855.0 65949.0 66550.0 61980.0 58002.0 58801.0 74568.0 52249.0 True False 70124.54481470508 59515.87482813085 84303.03647055369 70799.1094594148 62635.659842334106 59329.25988243677 61005.05975403438 61533.10912360423 66169.36660414892 61280.170032583745 1.144326864259982 0.9712093617965684 1.375698475146663 1.1553347424096518 1.0221195504031666 0.9681640871898749 0.995510614960711 1.004127584680101 1.0797843179770146 1.0 15.903132679828394 -6.269455992546525 5.520301146480022 1.0081323703521166 1.1640016716907575 0.37696714828600364 0.09456679190357277 0.1888071661070652 21.337303693060708 0.029765787665404386 0.03577549668114819 5.377049164883213e-07 6.269455992546525 0.15586930133864096 AES(ph)PSPAPPPGLR ddPTM_PC-9_AZD4547_30min_R2 4 AESPSPAPPPGLR 13 0 Q9BUA3 Q9BUA3 C11orf84 Uncharacterized protein C11orf84 1 AES(0.714)PS(0.286)PAPPPGLR;AES(0.957)PS(0.043)PAPPPGLR;AES(0.741)PS(0.259)PAPPPGLR;AES(0.972)PS(0.028)PAPPPGLR 166.62 0.00029535 231527000.0 274780.0 281869.0 375215.0 483136.0 405925.0 369582.0 329626.0 393233.0 317901.0 345859.0 True False 362154.32422094373 372977.6420012822 370239.4039388741 371756.4595767911 349569.3205255326 346471.9791153777 358962.07542982465 332467.87544539076 334704.5978522453 333750.581681287 1.0851046982347456 1.1175340582850426 1.1093296139703268 1.1138750911056017 1.0473968877134472 1.0381164801871086 1.075539924519482 0.9961566921338848 1.002858470436673 1.0 18.348410825657908 -7.0046412085543395 0.6495574781650588 0.9957549660525193 1.1126323670650193 0.7813359680554455 0.02146799238902178 0.3554333628787585 0.31589031182631977 0.018462210736783242 0.015702295933729103 9.893701231018226e-08 7.0046412085543395 0.11687740101249999 AES(ph)PSPAPPPGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AESPSPAPPPGLR 13 0 Q9BUA3 Q9BUA3 C11orf84 Uncharacterized protein C11orf84 1 AES(0.79)PS(0.21)PAPPPGLR;AES(0.987)PS(0.013)PAPPPGLR;AES(0.998)PS(0.002)PAPPPGLR;AES(0.864)PS(0.136)PAPPPGLR 193.0 1.924e-06 200270000.0 316580.0 327306.0 416286.0 405930.0 413780.0 396315.0 373401.0 366799.0 356948.0 279881.0 True False 370170.74125998444 359798.7765900037 426211.8370134471 383187.0581428166 332702.77934458386 375531.54372731555 338029.754090868 357170.91490566585 362167.68922072824 330621.209763223 1.119621882471137 1.0882507412264217 1.2891243042715923 1.1589911561246753 1.006295934803613 1.135836215699094 1.022407952390443 1.0803024862242099 1.095415776501748 1.0 18.33481975272315 -6.170582896579018 7.661396910429141 1.0630992342593621 1.1682947238238253 0.4127427175693945 0.062381021325804344 0.3070904855868554 23.018337908200326 0.01849874555865741 0.023939672464382562 6.751761664803507e-07 6.170582896579018 0.10519548956446312 AES(ph)PSPAPPPGLR ddPTM_PC-9_Lapatinib_30min_R1 4 AESPSPAPPPGLR 13 0 Q9BUA3 Q9BUA3 C11orf84 Uncharacterized protein C11orf84 1 AES(0.883)PS(0.117)PAPPPGLR;AES(0.981)PS(0.019)PAPPPGLR;AES(0.63)PS(0.37)PAPPPGLR;AES(0.976)PS(0.024)PAPPPGLR 187.62 3.3213e-05 208095000.0 404346.0 361279.0 421864.0 351512.0 383282.0 340735.0 346499.0 356436.0 394724.0 316226.0 True False 398579.9518920251 360442.48067241476 387179.97036213195 377363.36508965807 360738.10632140486 326162.55834207946 364439.02278737177 372997.3177935918 350266.02649200865 370885.24275534105 1.074671909108428 0.9718436840318961 1.0439346884921488 1.0174666489456157 0.9726407652174237 0.8794163820565828 0.9826193678667835 1.0056946861044131 0.944405401222895 1.0 18.50061333966991 -6.277029746236817 4.423019834606564 0.9605157389989583 1.0248664740588436 0.36347763746064 0.04081142719102823 0.23654735246978711 11.931382827935254 0.012824606865823467 0.01543048375663161 5.284090580864739e-07 6.277029746236817 0.06435073505988531 AES(ph)PTPGMAQGMEPGAGQEGAMFVHAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AESPTPGMAQGMEPGAGQEGAMFVHAR 27 0 A0A0A0MSQ9;Q86VX9-5;Q86VX9 A0A0A0MSQ9 MON1A Vacuolar fusion protein MON1 homolog A 1 AES(0.939)PT(0.061)PGMAQGMEPGAGQEGAMFVHAR 51.07 0.008287000000000001 10984000.0 15781.0 14772.0 42459.0 27964.0 37098.0 39519.0 28587.0 31947.0 32568.0 22808.0 True False 18452.411611042455 16238.466535253041 43471.383586654214 26397.26774051123 29828.91321022126 37446.554070776525 25879.032408042905 31108.425100644483 33044.24538739732 26942.90985197133 0.6848707772257326 0.6026990634816277 1.613462830313911 0.9797482115162043 1.1071155036373612 1.3898481743996436 0.9605136397748596 1.1546052475979456 1.2264542163020886 1.0 14.71761805077675 -5.227631487992551 24.97189525157815 1.1745383987303246 0.6437846170528247 0.5570773942003593 0.1908510041579456 432.1606936733158 319210.3346964357 0.046056526495136745 0.1218403032412231 5.920638051432337e-06 5.227631487992551 -0.5307537816774999 AES(ph)PTSAR ddPTM_PC-9_AZD4547_30min_R2 1 AESPTSAR 8 0 C9J6N8 C9J6N8 TFAP2A 1 AES(0.994)PT(0.006)SAR 100.25 0.0049517 15944000.0 19286.0 16651.0 23083.0 33144.0 27504.0 22655.0 21685.0 27564.0 23075.0 29867.0 True False 25418.546826279664 22033.110121947946 22776.904337835735 25503.162869695432 23685.544353597947 21238.379268630142 23614.92299058864 23304.617157707384 24294.697391453847 28821.36542080729 0.8819341642963592 0.7644714190411454 0.7902784620118025 0.8848700433631671 0.8218050743875726 0.7368970539229661 0.8193547615041197 0.8085882406141263 0.842940542085301 1.0 14.81485106479024 -8.838343041361268 2.160771064980652 0.9999841901711191 0.8113599331555852 0.622148245701911 0.043331830737659956 1.1232344908633283 6.8537521689216225 0.04198378351382954 0.011496406658467311 1.4509650737450503e-09 8.838343041361268 -0.18862425701553387 AES(ph)PTSAR ddPTM_PC-9_Lapatinib_30min_R1 2 AESPTSAR 8 0 C9J6N8 C9J6N8 TFAP2A 1 AES(0.923)PT(0.053)S(0.024)AR;AES(0.963)PT(0.037)SAR 77.533 0.023407 27650000.0 29036.0 37134.0 36115.0 34170.0 35465.0 34260.0 41476.0 41431.0 48134.0 32684.0 True False 28621.94131544973 37048.018504506144 33145.764107931514 36682.97578777849 33379.018426872724 32794.779663960704 43623.42433637338 43356.035511301605 42712.642046509296 38333.38585130752 0.7466583157165456 0.9664687238485214 0.8646709225347737 0.9569458834152857 0.8707558094749983 0.8555148191492744 1.1380008148924163 1.131025463794839 1.114241309447295 1.0 15.226313811425367 -7.26096284132799 24.994453506038486 1.1067356930247845 0.8837220301128917 0.7160384822120782 0.06733370266118746 22.021903711955378 1155094.622366532 0.025517400136158302 0.018540888193380744 5.4832387805551645e-08 7.26096284132799 -0.22301366291189273 AESCGS(ph)FDETESEESSK ddPTM_PC-9_AZD4547_30min_R2 2 AESCGSFDETESEESSK 17 0 A8MXB7;Q9Y343-2;Q9Y343 A8MXB7 SNX24 Sorting nexin-24 1 AESCGS(0.717)FDET(0.278)ES(0.005)EESSK;AESCGS(0.815)FDET(0.184)ESEESSK 226.79 4.7561999999999994e-29 24135200.0 71455.0 78578.0 89884.0 108129.0 111704.0 101245.0 83430.0 114869.0 90297.0 92565.0 True False 94176.20364366956 103976.80182345965 88692.07943083762 83201.52962639682 96195.82775139276 94914.134144889 90855.10837467431 97118.63547702381 95069.91507502082 89324.32752459338 1.0543175219286183 1.1640367714476447 0.9929218824112426 0.9314543073776762 1.0769275338222666 1.0625787708142174 1.0171373341675534 1.0872585125287895 1.0643227630103964 1.0 16.446765527116376 AESCGS(ph)FDETESEESSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AESCGSFDETESEESSK 17 0 A8MXB7;Q9Y343-2;Q9Y343 A8MXB7 SNX24 Sorting nexin-24 1 AESCGS(1)FDETESEESSK 233.84 3.2194999999999996e-37 12305000.0 21182.0 21266.0 22081.0 23558.0 26618.0 20735.0 21062.0 24309.0 20188.0 17242.0 True False 24767.69423642996 23377.147937902195 22607.494782658825 22238.121636066488 21402.393978911794 19647.620098118656 19066.85488432503 23670.91450751452 20483.21130805627 20367.83811240311 1.2160197906005317 1.147748121763917 1.1099604512710586 1.0918253333192223 1.0507936021878868 0.9646394472349094 0.9361256103422266 1.1621711826696022 1.0056644792155385 1.0 14.314005237122029 -5.433080014639413 0.924990581012592 1.0203748832340167 1.2243904437727446 0.5632871546045835 0.0577410553153594 0.7882315004273999 1.0038036815743927 0.023486441257275614 0.132728194142149 3.6890962420903e-06 5.433080014639413 0.20401556053872794 AESCGS(ph)FDETESEESSK ddPTM_PC-9_Lapatinib_30min_R1 2 AESCGSFDETESEESSK 17 0 A8MXB7;Q9Y343-2;Q9Y343 A8MXB7 SNX24 Sorting nexin-24 1 AESCGS(1)FDETESEESSK;AESCGS(0.77)FDET(0.229)ES(0.001)EESSK 318.62 1.0916999999999997e-147 30248000.0 61159.0 75646.0 90060.0 72253.0 80973.0 75601.0 77062.0 91200.0 79986.0 75915.0 True False 60286.861444812974 75470.8463346763 82655.61444165338 77566.7266489422 76210.3273390432 72367.7214645386 81051.89329273808 95437.4849419686 70977.13439007963 89036.80659962092 0.6771004458404469 0.8476364912103398 0.9283308510079167 0.871175973299928 0.85594183180608 0.8127843330001765 0.9103189612045584 1.071888004374754 0.79716621811526 1.0 16.442114229355234 -4.780139306553102 2.8169334491398224 0.9021848665373914 0.6352945382221873 0.435288690732091 0.07833046250170587 0.4187359414280629 4.56937171819193 0.020145646057360838 0.26244290113724195 1.6590546550922537e-05 4.780139306553102 -0.2668903283152041 AESGDS(ph)LGSEDRDLLYSIDAYR ddPTM_PC-9_AZD4547_30min_R2 1 AESGDSLGSEDRDLLYSIDAYR 22 1 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 AES(0.225)GDS(0.528)LGS(0.225)EDRDLLY(0.01)S(0.012)IDAYR 44.751999999999995 0.032729 4964600.0 6469.1 5798.7 6375.7 11821.0 7488.0 6069.6 6052.8 12336.0 10705.0 10294.0 True False 8526.139234360975 7673.0163752411 6291.154052191624 9095.851082629419 6448.420452288444 5690.066952499563 6591.487474172693 10429.754653079315 11270.844445309353 9933.610193249739 0.8583122418226967 0.7724297839324522 0.6333200044900795 0.9156641850925851 0.6491517511599547 0.5728095668950426 0.6635540700652676 1.0499460367557734 1.1346171458356917 1.0 13.278102419468299 -7.769464746569303 24.13515120943482 1.0692114774880945 0.7207346139541586 0.6913406752575353 0.10341841303142905 68.32432208667346 205469.8682889209 0.05768986706341419 0.028525708204315492 1.700337971315847e-08 7.769464746569303 -0.3484768635339359 AESGDS(ph)LGSEDRDLLYSIDAYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AESGDSLGSEDRDLLYSIDAYR 22 1 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 AES(0.157)GDS(0.657)LGS(0.185)EDRDLLYSIDAYR;AES(0.01)GDS(0.894)LGS(0.094)EDRDLLY(0.002)SIDAYR 60.669 0.0033795 8563900.0 10786.8 8430.5 15976.5 15601.2 11487.6 10729.0 13275.2 14289.9 12421.5 11499.0 True False 12612.792190988705 9267.424324766504 16357.440351213667 14727.115343772844 9236.6872444266 10166.352352674949 12017.676951875026 13914.805266400586 12603.140938330744 13583.677673966082 0.9285255800173957 0.6822470723468408 1.2041982108102922 1.084177326439233 0.6799842771688593 0.748424145263647 0.8847145257949997 1.0243768735082053 0.9278150763607566 1.0 13.729586510360472 -7.744780214366973 23.785606648228285 0.9820719608719702 0.8859939785830131 0.07251580112271028 0.15820061401757318 416.52077860986844 594702.1650459396 0.08057585698279629 0.04632445756479824 1.7997815093422017e-08 7.744780214366973 -0.09607798228895714 AESGDS(ph)LGSEDRDLLYSIDAYR ddPTM_PC-9_Lapatinib_30min_R1 1 AESGDSLGSEDRDLLYSIDAYR 22 1 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 AES(0.091)GDS(0.695)LGS(0.211)EDRDLLY(0.002)S(0.002)IDAYR 47.821999999999996 0.024297 7353500.0 7825.1 7133.9 6789.4 8272.5 8016.6 6275.9 6593.7 4849.5 8508.1 5497.8 True False 7713.512639052408 7117.381892855509 6231.201739841898 8880.887246251028 7545.079349242003 6007.494386837448 6935.089522778119 5074.825473970145 7549.82818373511 6448.087404641982 1.1962481515835914 1.1037973659804459 0.9663643416737888 1.3772901465103702 1.170126717545779 0.9316707435622924 1.0755265999939059 0.7870280217226545 1.1708631893389012 1.0 12.654655584574632 -6.75262727026348 24.96854082362889 0.9848637663417638 1.1604962564442927 0.2914154788673713 0.1320172858268649 242.04734206783073 685824.5801491075 0.04327206524422869 0.042645874579333755 1.7675541590022084e-07 6.75262727026348 0.1756324901025289 AESHNDCPVR ddPTM_PC-9_AZD4547_30min_R2 2 AESHNDCPVR 10 0 F8WD51;C9J486;C9JIP2;B4DND0;Q16831;C9K0J2 F8WD51 UPP1 Uridine phosphorylase 1 0 ; 106.4 0.0019486 4575800.0 25535.5 22393.6 32543.0 40260.0 36940.0 32365.0 26523.8 31751.0 29754.0 36073.0 False True 33655.25782860441 29631.89326928431 32111.45855678152 30978.679010799482 31811.518630813982 30341.211433644447 28884.366816590922 26844.612515395696 31326.735696005097 34810.095249766644 0.9668246405855503 0.8512442455750807 0.9224754579491358 0.8899337617011305 0.9138589941384098 0.8716210402741672 0.8297698299686369 0.7711731991188865 0.8999324900214142 1.0 15.087218141217422 -6.90604076046408 4.629136859782969 0.8554504735155167 0.9051797514848252 0.03323798519192567 0.06162615122594699 0.4529975529059866 16.974418264350543 0.021259805486135118 0.018626073229654195 1.2415357784826365e-07 6.90604076046408 0.04972927796930848 AESHNDCPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AESHNDCPVR 10 0 F8WD51;C9J486;C9JIP2;B4DND0;Q16831;C9K0J2 F8WD51 UPP1 Uridine phosphorylase 1 0 97.81299999999999 0.0041967 1770000.0 8902.0 9088.5 10006.0 15271.0 13160.0 9893.8 10202.0 10322.0 11618.0 8147.4 False True 10408.932777485576 9990.74621619599 10244.580987966321 14415.415379249991 10581.392469850443 9374.951710960524 9235.592703916245 10051.05843706302 11787.891270903403 9624.45912521709 1.0815083364230913 1.0380579403178294 1.0644318662151566 1.4977896619125426 1.0994272334874473 0.9740756949548645 0.9595960233981383 1.0443244972310386 1.2247848027135253 1.0 13.232489751144755 -6.5200546945101765 24.96393040150519 1.038098119149978 1.1715668700044575 0.16436593202300098 0.13799927351203728 219.90038580085573 1943893.1886744418 0.047912136543819414 0.048785098031235374 3.0195714153636857e-07 6.5200546945101765 0.1334687508544794 AESHNDCPVR ddPTM_PC-9_Lapatinib_30min_R1 2 AESHNDCPVR 10 0 F8WD51;C9J486;C9JIP2;B4DND0;Q16831;C9K0J2 F8WD51 UPP1 Uridine phosphorylase 1 0 ; 152.54 0.00014303 5199100.0 23490.0 32036.0 36115.0 31838.0 34519.0 36223.0 37641.0 30119.0 34658.0 25241.0 False True 23155.02829246157 31961.82261028596 33145.764107931514 34179.472728454544 32488.660286965143 34673.82672993718 39589.86680117248 31518.438694815293 30754.451075080386 29603.87321848161 0.7821621218809286 1.079650030062022 1.1196428204954854 1.1545608399348366 1.0974462715467437 1.1712598035411939 1.3373205090088227 1.0646728035282365 1.0388657878686114 1.0 14.853498322550143 -4.71654073936407 2.6758965162737804 1.1344843808378022 0.6739031039062211 0.571040771321365 0.0875783589263997 0.44674506353602494 3.6072465638774975 0.023175256036899215 0.49838295785293774 1.9206987805148017e-05 4.71654073936407 -0.46058127693158113 AESLPLSS(ph)NLQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AESLPLSSNLQSK 13 0 Q8N1W1-5;Q8N1W1-4;Q8N1W1-3;Q8N1W1;Q8N1W1-6;Q8N1W1-2 Q8N1W1-5 ARHGEF28 Rho guanine nucleotide exchange factor 28 1 AES(0.094)LPLS(0.285)S(0.622)NLQSK 143.25 8.5085e-05 5071600.0 19405.0 13354.0 19792.0 22586.0 26685.0 32599.0 24914.0 29024.0 29113.0 20025.0 True False 22689.883233779783 14679.69686648857 20263.916341577995 21320.579644799982 21456.26580987531 30889.45105274031 22553.965558260086 28262.150753469978 29538.722548615155 23655.37398218721 0.9591851412226898 0.6205649877927343 0.8566305633906686 0.9012996226926973 0.9070355778789269 1.3058111478601204 0.9534393992351802 1.1947454635361812 1.2487108667509623 1.0 14.529880349022232 -6.597512984463507 6.065405864862003 1.1404151527174935 0.8303460233643528 0.5696809088774959 0.12783681311367118 0.14897001420602288 9.276835545589593 0.041808567176352784 0.041840422958802 2.5263121777454215e-07 6.597512984463507 -0.3100691293531407 AESPES(ph)SAIESTQS(ph)TPQK ddPTM_PC-9_Lapatinib_30min_R1 1 AESPESSAIESTQSTPQK 18 0 Q9NTI5-2;Q9NTI5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 2 AES(0.042)PES(0.479)S(0.479)AIESTQS(0.959)T(0.041)PQK 159.54 9.321600000000001e-05 6909200.0 47174.0 75582.0 72649.0 64075.0 72123.0 79226.0 77370.0 78262.0 82340.0 71230.0 True False 46501.2901093479 75406.99452274441 66676.07965324969 68787.289247934 67880.86693927369 75837.6886648264 81375.84002568258 81898.3382294774 73066.00212136071 83542.01059199119 0.5566216300018734 0.902623649926536 0.7981143759980519 0.8233856087553671 0.8125357105755501 0.9077790698048706 0.9740708830089342 0.9803251998501535 0.8746019111056113 1.0 16.35021424457505 -3.3225853486663603 0.31050890519176066 0.972946986667912 3.937331390213822e-18 0.627493036361761 0.0749430225259482 13.297714919044157 0.5084000417737671 0.07678742065300026 5.816869223853813 0.00047578927847016436 3.3225853486663603 -0.972946986667912 AESPESSAIES(ph)TQSTPQKGR ddPTM_PC-9_Lapatinib_30min_R1 1 AESPESSAIESTQSTPQKGR 20 1 Q9NTI5-2;Q9NTI5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 AESPES(0.004)S(0.004)AIES(0.602)T(0.192)QS(0.163)T(0.034)PQKGR 59.996 0.0067932 3601800.0 12750.0 5154.4 7399.4 6602.2 4318.7 6019.5 4708.3 3813.1 8853.2 3876.8 True False 12568.182661936356 5142.465303485389 6791.049894509993 7087.747812293563 4064.6825568908816 5762.060017139852 4952.072736111171 3990.2705464059295 7856.059387671002 4546.89971448871 2.764121368652096 1.1309827852809042 1.4935561197600842 1.558808915382152 0.8939459438568127 1.2672502977752138 1.0891097334589053 0.877580504731811 1.7277837385851385 1.0 12.150667469301977 -4.759240993632541 24.998780979682692 1.2280407275408147 2.7641233467291157 0.7403108740982662 0.27319463787748327 28.988503364504723 329563.1679991909 0.06661944392436425 0.42922022175293906 1.7408405983426453e-05 4.759240993632541 1.536082619188301 AESPESSAIESTQS(ph)TPQKGR ddPTM_PC-9_Lapatinib_30min_R1 1 AESPESSAIESTQSTPQKGR 20 1 Q9NTI5-2;Q9NTI5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 AESPESSAIES(0.026)T(0.033)QS(0.895)T(0.045)PQKGR 97.662 0.00058402 0.0 9784.4 6469.1 6669.5 6181.5 4878.5 6473.5 4477.8 4370.1 5482.4 2192.0 True False 9644.872661760797 6454.121196410318 6121.159455014512 6636.1081308795065 4591.556221500032 6196.643495465544 4709.63857395633 4573.150799834403 4864.9143797686165 2570.8842793435965 3.7515779061916184 2.510467409314198 2.3809548738527346 2.581255089619923 1.7859832347927995 2.410315993315609 1.8319138717355279 1.7788240554343542 1.892311691684052 1.0 11.32804895769852 -1.5228787452803376 0.17751455280416598 1.145574388212084 10.216244729135404 0.7849141757246604 0.31944842174559585 27.089995581536776 0.302317315263555 0.7367112377351014 66.01383718438169 0.029999999999999995 1.5228787452803376 9.07067034092332 AESPESSAIESTQST(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 1 AESPESSAIESTQSTPQK 18 0 Q9NTI5-2;Q9NTI5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 AESPESSAIESTQS(0.013)T(0.987)PQK 205.68 3.3913e-67 0.0 8262.4 14032.0 13807.0 10620.0 13583.0 13026.0 12725.0 13251.0 14635.0 9949.3 True False 8144.576660861414 13999.509766123501 12671.841756561264 11401.03022728146 12784.07464520547 12468.908345089087 13383.838236096817 13866.68983515381 12986.65218661785 11669.023248391073 0.6979655869641351 1.199715646127773 1.0859385131749102 0.9770338086226229 1.095556532288865 1.0685477335738707 1.1469544580727598 1.1883333797510216 1.1129168149020914 1.0 13.510396185352453 -4.752592413834583 24.998616814464697 1.0996048478372622 0.6979648211532792 0.7554439005237645 0.06813711043396957 172.04157198787522 486097.0515264773 0.01753227369552875 0.20548506220620966 1.7676960284040303e-05 4.752592413834583 -0.401640026683983 AESPS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 2 AESPSPPR 8 0 P50219 P50219 MNX1 Motor neuron and pancreas homeobox protein 1 1 AES(0.001)PS(0.999)PPR;AES(0.001)PS(0.999)PPR 104.42 0.0038583 11473800.0 50126.0 48954.0 65657.0 101369.0 101675.0 80772.0 69429.0 90616.0 68252.0 72213.0 True False 66065.02531442995 64777.4231523536 64786.34528047825 77999.94318543788 87559.18128825145 75721.3140713217 75608.04649820499 76613.37934852735 71859.66138078047 69684.84484992652 0.9480544221158528 0.9295769157821682 0.9297049511985326 1.1193243430966773 1.2565024931435114 1.08662528035178 1.0849998541438197 1.0994267048096633 1.0312093186909956 1.0 16.08855731057548 -5.759991874173308 24.94323695685962 1.1067424416327203 0.9351585381507944 0.5685029408330677 0.06390911182985946 25.997229127401965 447962.1487632987 0.018300329580297134 0.029628257659517755 1.7378333440150625e-06 5.759991874173308 -0.17158390348192587 AESPS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AESPSPPR 8 0 P50219 P50219 MNX1 Motor neuron and pancreas homeobox protein 1 1 AESPS(1)PPR 123.86 0.0032984999999999998 5407400.0 22362.0 20979.0 31979.0 34106.0 38714.0 31212.0 30359.0 30666.0 25758.0 22820.0 True False 26147.44493036761 23061.656474619118 32741.500641032864 32195.151393143882 31128.26961077432 29575.187774414273 27483.175739873874 29861.049993312798 26134.662020651573 26957.0853569794 0.969965579887806 0.8554951757293106 1.2145786611368885 1.1943112902155166 1.1547342451365932 1.0971211235474694 1.0195158480943958 1.1077254680124955 0.9694913850871901 1.0 14.718376898014842 -5.250875404472968 24.987909331831542 1.1016372169024273 0.9127303675795755 0.4460355821531291 0.0808141875599283 636.0772208866404 1504562.3880601737 0.021409243567473483 0.05534714195840557 5.612089591892651e-06 5.250875404472968 -0.18890684932285184 AESPS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 2 AESPSPPR 8 0 P50219 P50219 MNX1 Motor neuron and pancreas homeobox protein 1 1 AESPS(1)PPR;AESPS(1)PPR 126.39 0.0035195 10628800.0 71845.0 61302.0 79167.0 58566.0 71453.0 61177.0 53000.0 51665.0 69380.0 47990.0 True False 70820.47712524048 61160.058985383665 72658.19485345735 62873.139010448795 67250.27502200304 58560.60232055232 55744.08066900831 54065.54451235544 61565.69379621084 56285.00755734447 1.25824762576583 1.0866136763519554 1.2908978430789317 1.1170494904241095 1.1948168427176082 1.0404298562257353 0.9903895031410442 0.9605674203254252 1.093820476678204 1.0 15.780463067341548 -6.823855449749864 4.168769316508004 1.0088722685261493 1.1861257544694792 0.6447763918912578 0.06415844820310677 0.13340716582514278 4.624772819954191 0.02177076230982893 0.019524403375494884 1.5001840725582206e-07 6.823855449749864 0.1772534859433299 AESPT(ph)PGMAQGMEPGAGQEGAMFVHAR ddPTM_PC-9_AZD4547_30min_R2 3 AESPTPGMAQGMEPGAGQEGAMFVHAR 27 0 A0A0A0MSQ9;Q86VX9-5;Q86VX9 A0A0A0MSQ9 MON1A Vacuolar fusion protein MON1 homolog A 1 AES(0.47)PT(0.53)PGMAQGMEPGAGQEGAMFVHAR;AES(0.462)PT(0.538)PGMAQGMEPGAGQEGAMFVHAR;AES(0.469)PT(0.531)PGMAQGMEPGAGQEGAMFVHAR 83.368 1.463e-06 26427000.0 30051.4 29922.0 90608.7 142454.0 105950.0 81415.9 49183.0 119091.0 66236.3 78225.0 True False 39607.12009204919 39593.70134339834 89407.16943532712 109613.43119236041 91240.67133012274 76324.95090253206 53560.19171990411 100688.22238893241 69737.41559391345 75486.36655983677 0.5246923636290441 0.5245145997590582 1.1844147958089302 1.4520957384466464 1.2087039751449398 1.0111090834135004 0.7095346373235206 1.3338597017928868 0.9238412016908216 1.0 16.20392848527741 -5.257121809660385 24.20152782861167 1.1137850279937156 0.52460335704505 0.5719166424343581 0.19996790588635474 166.3081397784275 932201.6456394438 0.05423781554783051 0.13316324958367753 5.531949289405651e-06 5.257121809660385 -0.5891816709486656 AESPT(ph)PGMAQGMEPGAGQEGAMFVHAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AESPTPGMAQGMEPGAGQEGAMFVHAR 27 0 A0A0A0MSQ9;Q86VX9-5;Q86VX9 A0A0A0MSQ9 MON1A Vacuolar fusion protein MON1 homolog A 1 AES(0.445)PT(0.555)PGMAQGMEPGAGQEGAMFVHAR;AES(0.457)PT(0.543)PGMAQGMEPGAGQEGAMFVHAR;AES(0.464)PT(0.536)PGMAQGMEPGAGQEGAMFVHAR 78.317 1.1575e-05 32607000.0 57726.0 59908.0 103810.0 75368.0 108513.0 94600.0 75463.0 77778.0 80204.0 62616.0 True False 67497.87165952954 65855.27032182089 106285.22410161741 71145.37530635286 87250.65661708837 89639.00946621773 68314.59833519213 75736.4099126029 81376.83176893934 73967.78513201661 0.9125306583002363 0.8903236754255028 1.4369123519370104 0.9618427154385337 1.1795764394102743 1.2118655345192688 0.923572312098642 1.0239107440817605 1.1001658576595092 1.0 16.174609456377404 -10.05457137648261 10.370320642643707 1.0000175121802968 1.0750030776330355 0.01674537956898514 0.16128519716468678 0.0 0.0 0.15552805231302255 0.03772109337842243 8.819188464881369e-11 10.05457137648261 0.07498556545273871 AESSAGDGPVPYS(ph)QGSSSLIMPRPNSVAATSSTK ddPTM_PC-9_AZD4547_30min_R2 1 AESSAGDGPVPYSQGSSSLIMPRPNSVAATSSTK 34 1 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 AESSAGDGPVPY(0.035)S(0.196)QGS(0.196)S(0.196)S(0.168)LIMPRPNS(0.044)VAAT(0.06)S(0.07)S(0.016)T(0.018)K 57.076 0.0011779000000000002 17076000.0 33016.0 32466.0 41774.0 60978.0 50106.0 50050.0 40810.0 52742.0 40239.0 48276.0 True False 43514.4012245385 42959.99959276691 41220.04946535328 46920.464200708644 43149.64679251668 46920.36558794697 44442.01094055436 44591.93579058924 42365.95139045333 46585.87193407079 0.9340686224811013 0.9221679837519133 0.884818674719423 1.0071822690602716 0.9262389003598104 1.0071801522648232 0.9539804471932937 0.9571986943530132 0.9094163022302219 1.0 15.507604875608552 -5.751418601603784 24.999592306078757 0.9636745230917502 0.9145333901590931 0.3426183466908811 0.0330293517072082 242.6729208210096 605408.3640397432 0.008668951956233214 0.014789313622930707 1.7724802241835315e-06 5.751418601603784 -0.049141132932657094 AESSAGDGPVPYS(ph)QGSSSLIMPRPNSVAATSSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AESSAGDGPVPYSQGSSSLIMPRPNSVAATSSTK 34 1 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 AESSAGDGPVPY(0.208)S(0.24)QGS(0.102)S(0.102)S(0.102)LIMPRPNS(0.24)VAAT(0.004)S(0.002)S(0.001)TK 66.413 3.8453e-05 19281000.0 50574.0 34982.0 35544.0 50269.0 51818.0 47254.0 43604.0 41558.0 29712.0 27693.0 True False 59135.17931796849 38454.78177201608 36391.50376137064 47452.590904296914 41664.634878625424 44775.91705408724 39473.51345437799 40467.14653434074 30146.48179041849 32713.521682332615 1.8076677861896249 1.1755011320833768 1.1124300255641497 1.4505497563083933 1.273621204198476 1.368728120710681 1.2066421291381846 1.2370159020878384 0.9215296990387772 1.0 14.997599456614655 -1.5228787453227646 0.11983672256106687 0.876051808257221 2.8254053657895035 0.43064397022739676 0.17895830966281775 107.87012962492828 0.8922606234156797 1.2777299921912892 35.08382351947373 0.029999999997069246 1.5228787453227646 1.9493535575322825 AESSAGDGPVPYS(ph)QGSSSLIMPRPNSVAATSSTK ddPTM_PC-9_Lapatinib_30min_R1 1 AESSAGDGPVPYSQGSSSLIMPRPNSVAATSSTK 34 1 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 AESSAGDGPVPY(0.182)S(0.203)QGS(0.06)S(0.162)S(0.162)LIMPRPNS(0.203)VAAT(0.017)S(0.006)S(0.002)T(0.002)K 53.522 0.0029054000000000003 16596000.0 34935.0 24368.0 30429.0 24880.0 21470.0 27065.0 19916.0 17041.0 26778.0 18549.0 True False 34436.820493705614 24311.57739316546 27927.24507933678 26709.758197246956 20207.176811644065 25907.493041596492 20947.153030263587 17832.787071229053 23761.979655159048 21755.1699350111 1.5829258331044171 1.1175080436416298 1.283706133427752 1.2277430273832208 0.9288448158303827 1.1908660386928516 0.9628586259192049 0.8197034141539999 1.092245187058656 1.0 14.409070665719561 -1.5228787452807266 0.3601213603629585 0.959773570954235 7.701371454821304 0.6238186855653189 0.1263405282611336 42.180098653302665 0.5886843059920379 0.10216988016244068 194.93960761561488 0.029999999999973125 1.5228787452807266 6.741597883867069 AESSAGDGPVPYSQGSSSLIMPRPNS(ph)VAATSSTK ddPTM_PC-9_AZD4547_30min_R2 1 AESSAGDGPVPYSQGSSSLIMPRPNSVAATSSTK 34 1 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 AESSAGDGPVPY(0.143)S(0.159)QGS(0.041)S(0.041)S(0.041)LIMPRPNS(0.514)VAAT(0.042)S(0.012)S(0.004)T(0.001)K 62.706 0.00027252 19032000.0 86879.0 82105.0 111030.0 143260.0 137950.0 108670.0 106970.0 122500.0 108120.0 116880.0 True False 114504.71480453937 108643.83559921528 109557.66965428682 110233.62034493609 118798.02369032975 101874.84772112263 116490.12277165182 103570.43976995927 113835.00246864514 112788.06677550313 1.0152201210474963 0.9632564747781638 0.9713586976568523 0.9773518023351576 1.0532853969985054 0.9032413679356477 1.0328231177462894 0.9182748027422891 1.0092823267839661 1.0 16.783254909952625 -6.749641176931531 24.99983417118182 0.9713726572537902 0.9918546611660239 0.06168954921079772 0.043888543241274745 774.3811019772032 1640872.7392884777 0.013692603529921615 0.013585489553519901 1.7797492683362839e-07 6.749641176931531 0.02048200391223376 AESSSGGGTVPSSAGILEQGPS(ph)PGDGSPPKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AESSSGGGTVPSSAGILEQGPSPGDGSPPKPK 32 1 Q68EM7-6;Q68EM7-5;Q68EM7;Q68EM7-7;Q68EM7-3 Q68EM7-6 ARHGAP17 Rho GTPase-activating protein 17 1 AESSSGGGTVPSSAGILEQGPS(0.723)PGDGS(0.277)PPKPK 125.79 1.0826e-16 15527000.0 47507.0 60006.0 34254.0 51537.0 48430.0 28997.0 51434.0 35540.0 29147.0 33481.0 True False 55548.996793979684 65962.99911416155 35070.7452690184 48649.54897520838 38940.48915766392 27476.346273698913 46561.799170087084 34607.11265774264 29573.21973429344 39550.840264549835 1.4044959961007275 1.6678027236069983 0.8867256683912471 1.2300509584574841 0.9845679357807985 0.6947095457369203 1.1772644742473728 0.8750032218344966 0.747726711657261 1.0 15.271420724882708 -5.265237274968541 24.917852910647547 0.9553479050111018 1.5361493825367776 0.659286717884086 0.16864899320511761 166.7695862777357 1094176.8128076124 0.04396103774069565 0.09747035628790734 5.429536100161316e-06 5.265237274968541 0.5808014775256758 AESSSGGGTVPSSAGILEQGPSPGDGS(ph)PPKPK ddPTM_PC-9_AZD4547_30min_R2 1 AESSSGGGTVPSSAGILEQGPSPGDGSPPKPK 32 1 Q68EM7-6;Q68EM7-5;Q68EM7;Q68EM7-7;Q68EM7-3 Q68EM7-6 ARHGAP17 Rho GTPase-activating protein 17 1 AESSSGGGTVPSSAGILEQGPS(0.134)PGDGS(0.866)PPKPK 88.10799999999999 1.1009e-09 55499000.0 19683.0 25876.0 18738.0 18015.0 19174.0 23763.0 23097.0 20692.0 19671.0 21036.0 True False 25941.784568166702 34239.91096724068 18489.52187680829 13861.920078975469 16512.021067331545 22277.095853474202 25152.588255182174 17494.526854857086 20710.76890085757 20299.536042860083 1.277949629656248 1.6867336718901915 0.9108347027129012 0.6828688128491043 0.8134186432866424 1.097418965952657 1.2390720754442586 0.8618190493575543 1.0202582392587307 1.0 14.30915913374246 -5.272684372037489 24.903689920566723 0.9489881595107847 1.482341649521928 0.6023257916942037 0.1719497051336777 417.5599210738832 924748.715823673 0.047815118623196484 0.10097805764182399 5.3372264296767755e-06 5.272684372037489 0.5333534900111432 AESSSGGGTVPSSAGILEQGPSPGDGS(ph)PPKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AESSSGGGTVPSSAGILEQGPSPGDGSPPKPK 32 1 Q68EM7-6;Q68EM7-5;Q68EM7;Q68EM7-7;Q68EM7-3 Q68EM7-6 ARHGAP17 Rho GTPase-activating protein 17 1 AESSSGGGTVPSSAGILEQGPS(0.011)PGDGS(0.989)PPKPK 79.78399999999999 1.6761e-07 18482000.0 74305.0 115270.0 71689.0 97911.0 94442.0 59302.0 96532.0 69049.0 60843.0 49532.0 True False 86883.36890935346 126713.24380710957 73398.33764204652 92425.36410174501 75936.7680575697 56192.09872479539 87387.7901288417 67236.53691346306 61732.71377135265 58511.75950490377 1.4848873054667227 2.1656030322672137 1.2544202783014093 1.5796032264932829 1.2978035304374256 0.9603556481682289 1.4935081574758982 1.149111520186435 1.0550479816997973 1.0 15.836438981586861 -5.829190058860362 0.962324753152359 1.1518785139539995 1.815884292087648 0.47176547745839936 0.24859179292170167 0.5641630986316162 1.0037595718471295 0.09865741235154045 0.2753193999939801 1.4818694375937431e-06 5.829190058860362 0.6640057781336484 AESSSGGGTVPSSAGILEQGPSPGDGS(ph)PPKPK ddPTM_PC-9_Lapatinib_30min_R1 2 AESSSGGGTVPSSAGILEQGPSPGDGSPPKPK 32 1 Q68EM7-6;Q68EM7-5;Q68EM7;Q68EM7-7;Q68EM7-3 Q68EM7-6 ARHGAP17 Rho GTPase-activating protein 17 1 AESSSGGGTVPSSAGILEQGPS(0.062)PGDGS(0.938)PPKPK;AESSSGGGTVPSSAGILEQGPS(0.043)PGDGS(0.957)PPKPK 107.05 6.091e-16 103149000.0 69280.0 132874.0 100861.0 111455.0 153874.0 125756.0 137136.0 153446.0 115677.0 121838.0 True False 68292.05449560395 132566.33841675415 92568.59791471896 119651.77250298056 144823.43384792356 120377.70903155413 144236.2310683987 160575.66134216406 102648.23812718781 142897.53596106955 0.4779092518026985 0.9277020595573462 0.6477970196766584 0.8373256522462222 1.013477474428801 0.8424057715337329 1.0093682168718001 1.1237118979148155 0.7183345565535357 1.0 17.124621514121806 -4.1206277732237755 0.5030105291936718 0.9677484801993619 1.3086444344914986e-16 0.43656204129499687 0.14073160106685284 8.139525918618851 0.9611065829352082 0.08086352212504605 5.3507328607769615 7.574818423157827e-05 4.1206277732237755 -0.9677484801993618 AESSSGGGTVPSSAGILEQGPSPGDGS(ph)PPKPKDPVSAAVPAPGR ddPTM_PC-9_AZD4547_30min_R2 2 AESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGR 44 2 Q68EM7-6;Q68EM7-5;Q68EM7;Q68EM7-7;Q68EM7-3 Q68EM7-6 ARHGAP17 Rho GTPase-activating protein 17 1 AESSSGGGTVPSSAGILEQGPS(0.096)PGDGS(0.85)PPKPKDPVS(0.054)AAVPAPGR;AESSSGGGTVPS(0.001)S(0.001)AGILEQGPS(0.233)PGDGS(0.711)PPKPKDPVS(0.055)AAVPAPGR 68.483 2.7578e-09 43891000.0 119801.0 78212.0 131753.0 195919.0 180951.0 150798.0 129284.0 123074.0 107032.0 144262.0 True False 157895.22598439953 103492.49948097952 130005.86913411913 150752.90146837602 155829.07709161929 141368.57722140316 140790.02554370576 104055.74125916701 112689.49300984129 139211.4312899351 1.1342116413956822 0.7434195491132916 0.9338735183560926 1.082906052121564 1.1193698365694889 1.0154954655050947 1.0113395447424351 0.7474654939970449 0.8094844795837443 1.0 17.086918156802838 -7.744421014699374 24.986020274428455 0.8338562439772514 1.0006504650923111 0.24931329758076815 0.1205493709148245 309.94174132470283 455051.5335122639 0.0589002427872079 0.03389392595884743 1.8012707024331068e-08 7.744421014699374 0.1667942211150597 AESSSGGGTVPSSAGILEQGPSPGDGS(ph)PPKPKDPVSAAVPAPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGR 44 2 Q68EM7-6;Q68EM7-5;Q68EM7;Q68EM7-7;Q68EM7-3 Q68EM7-6 ARHGAP17 Rho GTPase-activating protein 17 1 AESSSGGGTVPSSAGILEQGPS(0.248)PGDGS(0.679)PPKPKDPVS(0.073)AAVPAPGR 60.056000000000004 1.906e-06 11515000.0 94203.0 43901.0 52683.0 105100.0 99956.0 114030.0 106440.0 106830.0 88776.0 87059.0 True False 110149.70730593949 48259.20114839859 53939.162521390106 99211.58773879759 80370.3393401497 108050.06606165755 96357.23264113358 104025.82569574138 90074.1810523083 102842.1075413354 1.0710564956252666 0.46925527201007367 0.5244851920183599 0.9646981193857916 0.7814925351257158 1.0506403324944398 0.936943387730601 1.01151005344703 0.8758492334096198 1.0 16.650071555145736 -5.7777506916644485 24.84735223499573 0.943499528962337 0.6663646177517579 0.3352776359185181 0.16533890397914183 225.18479512339832 343027.9446994893 0.045691226464382145 0.06800229782950414 1.6682045766734478e-06 5.7777506916644485 -0.2771349112105791 AESSSGGGTVPSSAGILEQGPSPGDGS(ph)PPKPKDPVSAAVPAPGR ddPTM_PC-9_Lapatinib_30min_R1 2 AESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGR 44 2 Q68EM7-6;Q68EM7-5;Q68EM7;Q68EM7-7;Q68EM7-3 Q68EM7-6 ARHGAP17 Rho GTPase-activating protein 17 1 AESSSGGGTVPS(0.002)S(0.002)AGILEQGPS(0.123)PGDGS(0.835)PPKPKDPVS(0.039)AAVPAPGR;AESSSGGGTVPSSAGILEQGPS(0.08)PGDGS(0.862)PPKPKDPVS(0.058)AAVPAPGR 83.786 3.5964e-14 34459000.0 276600.0 125618.0 139235.0 146475.0 136693.0 134569.0 102551.0 87511.0 139114.0 112019.0 True False 272655.6332777725 125327.13923894687 127787.63576264298 157247.2601262758 128652.98648877794 128813.79756566047 107860.58899410316 91577.08053461216 123445.51638463662 131381.33489406478 2.0752996116047977 0.9539189059085179 0.9726468060754637 1.1968767120007358 0.9792333636472277 0.9804573661055083 0.8209734592898844 0.6970326539036346 0.9395970628870002 1.0 17.00340080360931 -4.7614220797685896 8.85147876850351 0.9453711611482807 2.0840419451864123 0.8862481197244113 0.12105419035994401 0.02857433899896012 28.653056577305204 0.03387930342210633 0.19454435102150805 1.732119776275047e-05 4.7614220797685896 1.1386707840381316 AET(ph)EEAEEPEEDGEEHVCVSASK ddPTM_PC-9_AZD4547_30min_R2 1 AETEEAEEPEEDGEEHVCVSASK 23 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 AET(1)EEAEEPEEDGEEHVCVSASK 122.65 6.2615e-05 0.0 17394.0 23006.0 19395.0 15381.0 20379.0 27833.0 30410.0 27740.0 23768.0 23982.0 True False 22924.930182324417 30442.239593149607 19137.809627532122 11835.148084081144 17549.727617145585 26092.598110076502 33116.43108802397 23453.420401785017 25024.327956666308 23142.397479552696 0.990603078292972 1.3154315416130344 0.8269588163646917 0.5114054451159612 0.7583366257818156 1.1274803370364042 1.430985321088006 1.0134395290076201 1.0813195987484174 1.0 14.498250710403369 -6.834832220662993 7.956228388922438 1.1519847181871414 0.8815899519705426 0.24298210445501933 0.21927336324745142 0.4009473015289131 37.99367305165618 0.08642368644570735 0.07633894653949051 1.4627421609362106e-07 6.834832220662993 -0.27039476621659886 AET(ph)EEAEEPEEDGEEHVCVSASK ddPTM_PC-9_Lapatinib_30min_R1 1 AETEEAEEPEEDGEEHVCVSASK 23 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 AET(1)EEAEEPEEDGEEHVCVSASK 145.52 5.7775999999999995e-06 19318000.0 48032.0 60524.0 49752.0 46642.0 49736.0 47434.0 54539.0 59629.0 57383.0 45962.0 True False 47347.054872010005 60383.86039658346 45661.5826082738 50072.20827315079 46810.62626473821 45405.35839405463 57362.762558623515 62399.58102636682 50919.9222702215 53906.470459484655 0.8783185852910809 1.1201597856785508 0.8470519813125662 0.9288719488838424 0.8683674866066481 0.8422988559078572 1.064116460782506 1.1575527111029364 0.9445975935021046 1.0 15.718170831368578 -7.281183441769295 23.96863826885764 1.054696114691418 0.9190753244162146 0.31830059302444613 0.09034760575905093 579.9054108942058 703981.9256101617 0.037910308720737536 0.025605448003163625 5.233793195510772e-08 7.281183441769295 -0.13562079027520335 AET(ph)PPLPIPPPPPDIQPLER ddPTM_PC-9_AZD4547_30min_R2 4 AETPPLPIPPPPPDIQPLER 20 0 U3KPW8;A0A669KB72;Q8IX15;Q8IX15-3 U3KPW8 HOMEZ Homeobox and leucine zipper protein Homez 1 AET(1)PPLPIPPPPPDIQPLER;AET(1)PPLPIPPPPPDIQPLER;AET(1)PPLPIPPPPPDIQPLER;AET(1)PPLPIPPPPPDIQPLER 135.09 1.215e-07 14225800.0 19540.7 19878.0 24922.1 36609.1 29676.420000000002 29260.85 23037.260000000002 29174.5 22907.25 23529.11 True False 25754.236128190558 26303.174764523512 24591.616670189134 28169.43759995674 25556.361335296704 27431.16442385771 25087.53151091388 24666.251388315686 24118.080468922268 22705.363020603705 1.1342798661629057 1.1584564730656373 1.0830752473710186 1.240651275841515 1.1255649738833022 1.208135910399919 1.1049165559761587 1.086362343818621 1.0622195490570492 1.0 14.47074548276569 -8.118152246849938 1.1180913423962564 1.0074258144583614 1.1567669325119112 0.5865251404799662 0.042893890863144685 0.3269880315261758 0.7742633752625433 0.03854992552576393 0.013210542292145992 7.618119014179946e-09 8.118152246849938 0.14934111805354977 AET(ph)PPLPIPPPPPDIQPLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AETPPLPIPPPPPDIQPLER 20 0 U3KPW8;A0A669KB72;Q8IX15;Q8IX15-3 U3KPW8 HOMEZ Homeobox and leucine zipper protein Homez 1 AET(1)PPLPIPPPPPDIQPLER;AET(1)PPLPIPPPPPDIQPLER;AET(1)PPLPIPPPPPDIQPLER 133.47 2.1601e-05 5850500.0 34198.130000000005 36154.1 40489.53 47001.57 50091.89 41146.4 42763.33 38717.4 38885.5 37107.5 True False 39987.19796514409 39743.24011387708 41454.95395259764 44368.224414045944 40276.743742141116 38988.61034990257 38712.47780270172 37701.10927447626 39454.12687336153 43834.79600719162 0.9122250268618501 0.9066596342174543 0.9457088370115027 1.0121690632885987 0.9188304135265792 0.8894443205234952 0.8831449288905205 0.8600726525176698 0.9000641149758883 1.0 15.419788913699737 -6.51967634522158 23.764109539785508 0.8972038910365961 0.9446034704741055 0.12411588454029177 0.043893330491840375 114.99409084554564 853353.7854995718 0.014377319228111366 0.0146737769044542 3.022203156108336e-07 6.51967634522158 0.04739957943750939 AET(ph)PPLPIPPPPPDIQPLER ddPTM_PC-9_Lapatinib_30min_R1 3 AETPPLPIPPPPPDIQPLER 20 0 U3KPW8;A0A669KB72;Q8IX15;Q8IX15-3 U3KPW8 HOMEZ Homeobox and leucine zipper protein Homez 1 AET(1)PPLPIPPPPPDIQPLER;AET(1)PPLPIPPPPPDIQPLER;AET(1)PPLPIPPPPPDIQPLER 164.01 1.4364000000000003e-21 7173400.0 24639.1 20872.800000000003 21804.699999999997 17547.800000000003 19535.5 19227.2 16407.4 19895.800000000003 22752.0 16600.5 True False 24287.741915742445 20824.470314021022 20012.001734576046 18838.32374974479 18386.460298270755 18404.897476792332 17256.89488997523 20820.23150118882 20189.43017081855 19469.87430622417 1.24745242489717 1.069573947242372 1.0278444236375253 0.967562679319533 0.9443543398938602 0.9453012991927029 0.8863382792593842 1.0693562358814492 1.036957396502778 1.0 14.248955949875125 -4.498653539517191 1.2200148553065933 0.9758532596953438 1.5359356851700157 0.7290505614703919 0.049186961475923156 1.4727764621181954 1.2012176390202125 0.016000097043370267 1.229604383789329 3.172097009365115e-05 4.498653539517191 0.5600824254746719 AET(ph)PTES(ph)VSEPEVATK ddPTM_PC-9_Lapatinib_30min_R1 1 AETPTESVSEPEVATK 16 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 2 AET(0.999)PT(0.123)ES(0.562)VS(0.316)EPEVATK 123.4 0.008556999999999999 0.0 9575.5 11513.0 10461.0 9932.1 13278.0 10065.0 9557.8 9622.1 10433.0 10051.0 True False 9438.951614068365 11486.342355856612 9600.936960627754 10662.539766514334 12497.014145552394 9634.543412660963 10052.656117325427 10069.177893203043 9257.925675639499 11788.301957884343 0.8007049401848187 0.974384809355365 0.8144461343905753 0.9045017513640233 1.0601199553761043 0.8172969649981788 0.8527654070314963 0.8541669469595236 0.7853485352440893 1.0 13.525068300295604 -9.48411310914774 10.527680670868943 1.0000000370497806 0.878496714828509 0.17496626346626698 0.0816626338708684 103881978.71398261 0.0 0.07917154804516004 0.019792887011290027 3.28009853973678e-10 9.48411310914774 -0.12150332222127158 AET(ph)PTESVSEPEVATK ddPTM_PC-9_AZD4547_30min_R2 1 AETPTESVSEPEVATK 16 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 AET(0.968)PT(0.031)ES(0.001)VSEPEVATK 169.37 8.4044e-05 55064000.0 13182.0 12510.0 16055.0 13268.0 14350.0 14620.0 15503.0 17460.0 14080.0 13914.0 True False 17373.601797366922 16553.612853616523 15842.100209849355 10209.26758855656 12357.750199030339 13705.809088826876 16882.736966709494 14761.958190885603 14824.240055110298 13426.875095091997 1.2939423115448208 1.2328715904765855 1.179879912314088 0.7603606584743172 0.9203742577115013 1.0207743046508893 1.2573839294059375 1.0994336423284095 1.1040722394542188 1.0 13.712835957628926 -5.536538221031459 24.981828893760326 1.0279001317125387 1.2491492409324554 0.3973844527913297 0.12240171800420183 250.8496143470481 458777.5349731942 0.03732577120945508 0.06469140212303774 2.9071121014556485e-06 5.536538221031459 0.2212491092199167 AET(ph)PTESVSEPEVATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AETPTESVSEPEVATK 16 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 AET(0.998)PT(0.002)ESVSEPEVATK;AET(0.999)PT(0.001)ESVSEPEVATK 233.47 1.4578e-50 26698000.0 35463.0 39498.0 32780.0 36101.0 43617.0 33737.0 39800.0 33756.0 30308.0 27905.0 True False 41466.185473822836 43419.100406811835 33561.5995188423 34078.37801102118 35070.56195725435 31967.772329405816 36029.855872953005 32869.940767438406 30751.197162897264 32963.95560414155 1.2579250491592422 1.317168999018938 1.0181302244754165 1.03380730214124 1.0639063581570936 0.9697796196943496 1.0930076567760654 0.9971479503906585 0.9328733945702112 1.0 15.008601752776507 -5.265381722564213 24.952966469815564 1.017271649607062 1.287547037314327 0.8569922588392895 0.04474557155054573 100.0226959316613 633095.4390756725 0.011577758750923824 0.02564351860846629 5.427730521101593e-06 5.265381722564213 0.270275387707265 AET(ph)PTESVSEPEVATKQELQEEEEQTKPPR ddPTM_PC-9_AZD4547_30min_R2 2 AETPTESVSEPEVATKQELQEEEEQTKPPR 30 2 M0R0Q7;P18858-2;P18858;P18858-3;B4E135 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 AET(0.301)PT(0.301)ES(0.301)VS(0.094)EPEVAT(0.003)KQELQEEEEQTKPPR;AET(0.895)PT(0.049)ES(0.055)VS(0.001)EPEVATKQELQEEEEQTKPPR 69.07 4.4625e-05 9614500.0 26061.2 14011.0 25532.5 62184.0 47112.0 30689.9 16510.5 23711.5 21461.7 35684.0 True False 34348.1194933651 18539.78174996171 25193.92236736085 47848.43953322288 40571.31201231479 28770.85570144922 17979.90251492338 20047.43251106438 22596.121647071057 34434.71402136426 0.9974852549103373 0.5384038252345905 0.731643142200334 1.3895407844402705 1.178209640049376 0.835518938348057 0.5221446736502049 0.5821866996957312 0.6562018094023313 1.0 15.071576075116335 -7.0064526773434395 24.19604079045074 0.6586749489814109 0.9589582248244027 0.215641804318903 0.24586477600673862 308.37182225491586 1156326.5105646 0.0967504665969607 0.08230148793562006 9.852519943905082e-08 7.0064526773434395 0.30028327584299186 AETEEAAHSVSQEMSVNS(ph)PTAQESQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AETEEAAHSVSQEMSVNSPTAQESQR 26 0 F8WAI8;Q9NUA8;B1AKC8;A0A3B3IRZ6;Q9NUA8-2 F8WAI8 ZBTB40 Zinc finger and BTB domain-containing protein 40 1 AETEEAAHS(0.001)VSQEMS(0.137)VNS(0.628)PT(0.232)AQES(0.002)QR 94.34899999999999 0.0002598 0.0 6765.1 9700.3 10297.0 10464.0 12219.0 9926.1 7746.6 8746.4 9286.7 9033.7 True False 7910.297813184421 10663.281676950657 10542.519531589965 9877.736004745728 9824.774664825427 9405.557842099617 7012.785967472814 8516.816267576829 9422.500418789687 10671.43829927015 0.7412588248507634 0.9992356585784644 0.9879192697305852 0.9256236814320796 0.920660775923464 0.8813767721210448 0.6571547124957315 0.79809450504524 0.8829644284626673 1.0 13.381467015635097 -7.010124476326504 23.747316907627688 0.8108047836167462 0.9219455721039328 0.09916681800527938 0.10380795049131085 414.07853632609687 971236.9099270224 0.03731749548118582 0.030977131818949705 9.769571679649508e-08 7.010124476326504 0.11114078848718656 AETEEAAHSVSQEMSVNSPT(ph)AQESQR ddPTM_PC-9_Lapatinib_30min_R1 1 AETEEAAHSVSQEMSVNSPTAQESQR 26 0 F8WAI8;Q9NUA8;B1AKC8;A0A3B3IRZ6;Q9NUA8-2 F8WAI8 ZBTB40 Zinc finger and BTB domain-containing protein 40 1 AETEEAAHSVSQEMS(0.036)VNS(0.354)PT(0.603)AQES(0.007)QR 79.286 0.00050678 0.0 5625.3 6271.6 7881.1 5463.0 6315.9 7408.4 5408.3 5762.9 6818.5 3987.1 True False 5545.082190446322 6257.078495525958 7233.146379925768 5864.767244033763 5944.411179537159 7091.56000182389 5688.315310984865 6030.665372500785 6050.528728011879 4676.264922523195 1.1857929955461837 1.338050473870457 1.546778572165014 1.2541563280100225 1.2711878556978127 1.5165009081644292 1.2164228086366828 1.2896329597269245 1.2938806565191703 1.0 12.191140949258742 -9.474924420817363 0.5837727165087055 0.9786346828619495 1.3464675800622998 0.4378979389186388 0.11159666876389028 3.776242211403062 1.5683834799700318 0.3020167519086542 0.047806471116504115 3.3502373742815383e-10 9.474924420817363 0.3678328972003503 AETEELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AETEELK 7 0 Q7Z6J4 Q7Z6J4 FGD2 FYVE, RhoGEF and PH domain-containing protein 2 0 92.925 0.024582 0.0 59082.0 80111.0 63037.0 90153.0 48265.0 94701.0 60277.0 56046.0 75873.0 74700.0 False True 69083.41567730877 88063.89064484532 64540.04114915378 85102.01968996967 38807.81972320151 89734.71284841749 54567.12619231126 54574.85188564563 76982.4990873863 88242.51867512554 0.7828812766739683 0.9979757147352303 0.7313939143868387 0.9644105921690885 0.4397859479292146 1.0169101493893848 0.6183767985273186 0.618464349216605 0.8723968926001056 1.0 16.429186349402762 AETEQGEQQR ddPTM_PC-9_AZD4547_30min_R2 2 AETEQGEQQR 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 128.91 0.0012165999999999998 4748600.0 6181.9 5335.799999999999 7043.700000000001 6037.6 7108.2 5159.0 6159.4 6124.0 7775.2 6305.4 False True 8147.615608492086 7060.493002743969 6950.295935728177 4645.724599990134 6121.349126463234 4836.40691444992 6707.574667661131 5177.676515520243 8186.181198614602 6084.649865214392 1.3390442817542478 1.1603778621853689 1.1422671952683154 0.7635155190357765 1.0060314499703014 0.794853774922924 1.1023764417420245 0.8509407492977918 1.345382459131223 1.0 12.570958531618778 -5.219552813875132 1.9738582662278674 0.9748447646884367 1.3089872844774135 0.30741357172174966 0.1633916438877239 0.4484983655781111 3.0719521530049785 0.043966373960956415 0.19376742783580617 6.0318035164377535e-06 5.219552813875132 0.3341425197889768 AETEQGEQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AETEQGEQQR 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 112.36 0.00674 2208800.0 5055.4 9271.6 7741.8 5926.5 11743.0 10134.0 6425.9 7586.7 9383.5 8457.0 False True 5911.179371298652 10192.023174130254 7926.393872940001 5594.457418972241 9442.043447830842 9602.555200112585 5817.1922325127825 7387.557163773105 9520.715935662076 9990.18715442483 0.591698561791256 1.0202034272817428 0.79341795608196 0.5599952565948033 0.9451317880114782 0.9611987294812034 0.5822906160407861 0.7394813580145018 0.9530067643873101 1.0 13.286295990130375 -8.362294882560596 4.769724506754451 0.9936815257307618 0.7817071966038087 0.21256931228881426 0.1559606415347905 0.3693817103114197 12.78730612171434 0.14956700048731947 0.03924084298119992 4.342152952622048e-09 8.362294882560596 -0.21197432912695313 AETEQGEQQR ddPTM_PC-9_Lapatinib_30min_R1 1 AETEQGEQQR 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 120.45 0.0032473 2370800.0 1311.1 2835.4 3559.2 3744.1 3440.7 2405.6 4797.8 4202.0 4280.4 2875.4 False True 1292.4034735737062 2828.834805506458 3266.5763149093136 4019.4536039514583 3238.3247906764664 2302.718095727491 5046.206608184305 4397.240260155181 3798.2962773897516 3372.409058770334 0.3832285618533326 0.8388172241886703 0.9686180584808387 1.1918641937870529 0.960240805383568 0.6828110278434374 1.4963210334941635 1.3038869791669123 1.1262857533583743 1.0 11.71956382428336 -4.7034627868313255 1.2098722319781123 1.1178242605296609 3.207497353914363e-17 0.53317754027648 0.20506128249801275 1.5074375668271858 1.6714893609165908 0.06664879765877811 2.2231253627641943 1.9794166232288267e-05 4.7034627868313255 -1.1178242605296609 AETFAGYDCTNS(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 3 AETFAGYDCTNSPTK 15 0 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 AETFAGYDCTNS(0.995)PT(0.005)K;AETFAGYDCT(0.069)NS(0.86)PT(0.071)K;AETFAGYDCT(0.002)NS(0.981)PT(0.017)K 193.54 1.5059e-09 14698700.0 60924.5 67099.0 77675.0 65672.0 66662.0 92957.0 87448.0 84000.0 75062.1 84764.0 True False 80297.22369167658 88787.43955753915 76644.97874805662 50532.33502228565 57407.131969878734 87144.3840950808 95230.70259077696 71019.73012797194 79029.7293636856 81796.43816015357 0.9816713966744909 1.0854682863292595 0.9370209812558019 0.6177816071079492 0.7018292392815232 1.065381159072675 1.164240213055729 0.8682496661886261 0.966175681255816 1.0 16.319750401682697 -6.79756744012347 24.99998169083326 1.0140394185619452 0.8673099259279468 0.2115288983459198 0.14287007106612845 335.0900224638367 231874.1194860219 0.05742293230338519 0.0506439118126569 1.5937953663947282e-07 6.79756744012347 -0.14672949263399848 AETFAGYDCTNS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AETFAGYDCTNSPTK 15 0 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 AETFAGYDCTNS(0.5)PT(0.5)K;AETFAGYDCT(0.002)NS(0.992)PT(0.006)K;AETFAGYDCT(0.009)NS(0.498)PT(0.493)K 176.25 2.0547e-28 4735300.0 41871.0 53064.0 48654.0 47443.0 55392.0 41702.0 58076.0 39529.0 38015.0 33052.0 True False 48958.93331005376 58331.84323224123 49814.095881322544 44784.92252228129 44538.33523479908 39515.07370782466 52574.62084617137 38491.405634437535 38570.8974576857 39044.06596051196 1.2539404415403206 1.4940002224982505 1.27584293940347 1.1470353156245425 1.1407197006542267 1.012063491230372 1.3465457439638542 0.9858452158483348 0.9878811673122158 1.0 15.252815679264376 -5.5932508254403075 0.3836422049316861 1.005101773880355 1.5287541713407724 0.5048436247945963 0.11698498513970929 2.7357453314758793 0.5044964561415821 0.11323835701699285 0.6250904755266329 2.551227423544877e-06 5.5932508254403075 0.5236523974604175 AETFAGYDCTNS(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 1 AETFAGYDCTNSPTK 15 0 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 AET(0.01)FAGYDCT(0.018)NS(0.949)PT(0.024)K 187.78 2.9735e-07 6073300.0 29293.0 49208.0 48799.0 40917.0 61389.0 53579.0 50237.0 50447.0 55285.0 46987.0 True False 28875.27644832172 49094.0618993305 44786.934589587414 43926.172675110654 57778.21971541769 51287.551068749286 52838.02604847119 52790.95178582778 49058.22112314096 55108.640343757965 0.5239700393296377 0.8908596109991177 0.8127025872932888 0.7970832232678388 1.0484421200560812 0.9306626102336513 0.9587974901735357 0.9579432817889745 0.8902092451768805 1.0 15.749990912571516 -4.271901048858887 0.8619199018650433 0.9459284425026704 4.278159056426788e-31 0.7090475470557629 0.07551521996662573 2.873502021630449 0.9000386465352461 0.026394671434123017 3.169620499027178 5.346861702465157e-05 4.271901048858887 -0.9459284425026704 AETFAGYDCTNSPT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 AETFAGYDCTNSPTK 15 0 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 AET(0.002)FAGYDCTNS(0.286)PT(0.712)K 179.66 6.8577e-05 5909800.0 17641.0 35619.0 34187.0 29780.0 43101.0 33546.0 34491.0 34019.0 36086.0 26063.0 True False 17389.4361050368 35536.526393924825 31376.276825636276 31970.120543167774 40565.88391982635 32111.315779545424 36276.775214240886 35599.64693246527 32021.614677573754 30567.954823235472 0.5688779705935266 1.1625418383212414 1.026443444027416 1.0458704459634467 1.3270722282339675 1.0504895065840913 1.1867583364349255 1.1646067634660688 1.047555024951598 1.0 14.899732410181958 -4.758741780371647 24.998599793159954 1.119851695541063 0.568877236109257 0.7470531158511362 0.09478556506655147 35.0688480080039 324919.1546063951 0.02288569527196512 0.15314024387944858 1.7428428120895617e-05 4.758741780371647 -0.5509744594318059 AETPTES(ph)VSEPEVATK ddPTM_PC-9_Lapatinib_30min_R1 1 AETPTESVSEPEVATK 16 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 AETPTES(0.573)VS(0.427)EPEVATK 223.14 1.5985e-28 22817000.0 36746.0 46590.0 40026.0 33239.0 40170.0 39487.0 35845.0 41182.0 39088.0 32978.0 True False 36221.9953016089 46482.12371748105 36735.2167848281 35683.50694205354 37807.27957725862 37798.23305869282 37700.878709068 43095.46606228241 34685.4978251123 38678.203359577165 0.9364963249421439 1.2017653272400914 0.9497653353573374 0.922574055736689 0.9774828273634666 0.9772489354610507 0.9747319015461153 1.1142054779959545 0.8967711737449092 1.0 15.23923316132315 AETPTES(ph)VSEPEVATKQELQEEEEQTKPPR ddPTM_PC-9_AZD4547_30min_R2 1 AETPTESVSEPEVATKQELQEEEEQTKPPR 30 2 M0R0Q7;P18858-2;P18858;P18858-3;B4E135 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 AET(0.089)PT(0.102)ES(0.403)VS(0.403)EPEVAT(0.003)KQELQEEEEQTKPPR 68.024 3.6432e-05 4533100.0 10039.0 5096.1 12378.0 31051.0 25667.0 14456.0 6701.4 10059.0 6493.3 15268.0 True False 13231.193175828153 6743.314665332949 12213.859632358472 23892.67168316775 22103.58009466979 13552.064034752475 7297.811617668002 8504.612682824638 6836.522581665321 14733.471967217522 0.8980363355811862 0.45768673401198673 0.8289871972834867 1.6216592895639101 1.5002288763877931 0.9198146957422039 0.49532191963346334 0.5772307234674686 0.46401300364753245 1.0 13.846809823477324 -7.108271667864016 5.139053724730067 0.6032327430335264 1.0601643235532943 0.2596044874256871 0.3381691896860483 0.3449818547485389 13.528491834962136 0.14827084418786854 0.1146237537540846 7.793424494052547e-08 7.108271667864016 0.4569315805197679 AETPTESVS(ph)EPEVATK ddPTM_PC-9_AZD4547_30min_R2 4 AETPTESVSEPEVATK 16 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 AETPTES(0.015)VS(0.985)EPEVATK;AETPTES(0.002)VS(0.998)EPEVATK;AET(0.002)PT(0.001)ES(0.124)VS(0.874)EPEVATK;AETPTES(0.002)VS(0.998)EPEVATK 195.45 8.314e-12 63450000.0 167085.0 169404.0 205027.0 196910.0 194862.0 225574.0 210512.0 233436.0 198605.0 186776.0 True False 220214.55441610183 224160.53012422493 202308.20801773807 151515.44172917353 167808.77486295797 211468.82212059075 229247.16018421878 197363.83002563388 209102.8548398564 180237.02909018984 1.2218052834520892 1.2436985410587076 1.1224564066494012 0.8406454683258003 0.9310449451482424 1.1732817789332992 1.2719204335614325 1.0950237641060643 1.1601548022366825 1.0 17.459535912873264 -1.5228787457625361 0.008000549990326953 1.1291813555634968e-08 2.327137590869678 0.042397827273176314 0.13129297681342308 119524.61077984158 74.23220032289127 9587.42382524027 12144.490409077342 0.029999999966690904 1.5228787457625361 2.3271375795778644 AETPTESVS(ph)EPEVATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AETPTESVSEPEVATK 16 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 AETPTES(0.002)VS(0.998)EPEVATK;AETPT(0.004)ES(0.022)VS(0.974)EPEVATK;AETPTES(0.039)VS(0.96)EPEVAT(0.001)K;AETPTESVS(1)EPEVATK 289.59 6.588199999999998e-97 50300000.0 101521.0 129552.0 137079.0 121982.0 139816.0 113198.0 133078.0 98923.0 89531.0 89525.0 True False 118706.5001688514 142413.06638065926 140347.48323500223 115147.74401098 112420.058477554 107261.69760630999 120471.88843871461 96326.37606758231 90840.22149898899 105755.17382049013 1.1224651795319724 1.3466297792899722 1.3270980337399796 1.0888142854025553 1.0630218306706858 1.0142453908531892 1.139158341729973 0.9108431539348386 0.8589671617691449 1.0 16.69036871993405 -6.354242448262117 0.8195881192539033 0.9538562690281843 1.2810068971521866 0.6144275823607104 0.09324587209556522 0.447399887272368 0.6564960490574351 0.05472640405916902 0.08268411123685966 4.423413629257298e-07 6.354242448262117 0.3271506281240023 AETPTESVS(ph)EPEVATK ddPTM_PC-9_Lapatinib_30min_R1 3 AETPTESVSEPEVATK 16 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 AETPTES(0.004)VS(0.996)EPEVATK;AETPT(0.001)ES(0.284)VS(0.708)EPEVAT(0.007)K;AETPTES(0.068)VS(0.932)EPEVATK 241.8 6.692e-38 45480000.0 87409.0 94633.0 99539.0 83913.0 98728.0 94700.0 87390.0 88277.0 89558.0 78329.0 True False 86162.53163115242 94413.88310273412 91355.28765165157 90084.2419455621 92921.01314671627 90649.90175648217 91914.62659744601 92378.67169103239 79471.03495245115 91868.06328316814 0.9378942861304329 1.0277116957578492 0.9944183472123928 0.9805827915180088 1.011461544152755 0.9867400978843845 1.000506849851992 1.0055580621776077 0.8650561698192636 1.0 16.487275794374533 -8.20830868016024 24.999868290251577 0.9325273651729651 0.9945347612778859 0.2932506687033931 0.03756714311867249 307.5948264500318 144734.42721874546 0.022889028056337038 0.008651225702031385 6.1900095612009016e-09 8.20830868016024 0.06200739610492079 AETSEGSGSAPAVPEASAS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 AETSEGSGSAPAVPEASASPK 21 0 I6LM39;A0A087X1U4;P51608;P51608-2;A0A087WVW7;A0A0D9SFX7;B5MCB4 I6LM39 MECP2 Methyl-CpG-binding protein 2 1 AETSEGSGSAPAVPEAS(0.024)AS(0.976)PK;AETSEGSGSAPAVPEASAS(1)PK 325.6 1.2244999999999996e-187 50790000.0 86810.0 106530.0 79801.0 66631.0 77296.0 83829.0 117008.0 114222.0 96423.0 89531.0 True False 114413.77423982884 140963.7391923076 78742.78659895291 51270.252388687986 66564.78462608013 78587.1593780619 127421.48532546918 96571.61446044309 101519.72292854401 86396.54694111543 1.3242864245235273 1.6315899672284713 0.9114112703210345 0.5934294159190392 0.7704565400217688 0.9096099573472987 1.474844653366931 1.1177716920360554 1.1750437549053432 1.0 16.398686032094666 -7.2106327318985155 24.999723681932647 1.2017310989655083 1.0149653749752454 0.07269605304441018 0.29295969218793566 1090.061694544675 536371.9897592014 0.12728163549107532 0.09859177248035772 6.15697326943538e-08 7.2106327318985155 -0.18676572399026292 AETSEGSGSAPAVPEASAS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AETSEGSGSAPAVPEASASPK 21 0 I6LM39;A0A087X1U4;P51608;P51608-2;A0A087WVW7;A0A0D9SFX7;B5MCB4 I6LM39 MECP2 Methyl-CpG-binding protein 2 1 AETSEGSGSAPAVPEASAS(1)PK;AETSEGSGSAPAVPEAS(0.005)AS(0.995)PK;AETSEGSGSAPAVPEASAS(1)PK 300.34 2.485999999999999e-132 38241400.0 107468.0 136938.0 72971.0 93913.0 145604.0 81187.0 103244.0 75365.0 75729.0 74298.0 True False 125660.20981024721 150532.29964828573 74710.90538405871 88651.359080054 117073.94142705944 76929.41079845469 93463.98089817005 73386.74860581821 76836.39335980745 87767.63925735543 1.4317373792153827 1.7151230330679113 0.8512352162622114 1.0100688571571041 1.3339078322907947 0.876512248129171 1.0649025277313384 0.836148143288108 0.8754524333792892 1.0 16.421401482308013 -5.261727173823754 24.999974240561137 0.9880793284403854 1.5734302344841924 0.7063925599494472 0.15271543343003427 13.010504679207529 1130313.7322385272 0.040229011300003004 0.09313990451559095 5.473597092833904e-06 5.261727173823754 0.585350906043807 AETSEGSGSAPAVPEASAS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 AETSEGSGSAPAVPEASASPK 21 0 I6LM39;A0A087X1U4;P51608;P51608-2;A0A087WVW7;A0A0D9SFX7;B5MCB4 I6LM39 MECP2 Methyl-CpG-binding protein 2 1 AETSEGSGSAPAVPEAS(0.002)AS(0.998)PK;AETSEGSGSAPAVPEAS(0.347)AS(0.653)PK;AETSEGSGSAPAVPEASAS(1)PK 338.67 5.0740999999999974e-210 58643500.0 158530.0 232067.0 155619.0 163799.0 138751.0 191308.0 187534.0 156965.0 161634.0 124089.0 True False 156269.33312915862 231529.6631196538 142824.60652671158 175845.32487744596 130589.9389749618 183126.20280072943 197243.59290909086 164258.16692890483 143429.07683852335 145537.6183118012 1.0737384254452047 1.5908578538342053 0.9813586905120487 1.208246547643189 0.8972933629790798 1.2582740113858266 1.3552756682228666 1.1286303076431865 0.9855120518135697 1.0 17.151032581090945 -1.5229772291159134 0.024854649493772182 0.12011902836684389 2.5710785699971503 0.09806541900804466 0.18986820172579255 4912.533314309552 9.424295449466781 320.4972145978694 667.0638418971668 0.02999319774894265 1.5229772291159134 2.4509595416303065 AEVDMDTDAPQVS(ph)HKPGGEPK ddPTM_PC-9_AZD4547_30min_R2 1 AEVDMDTDAPQVSHKPGGEPK 21 1 Q14204 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 1 AEVDMDT(0.002)DAPQVS(0.998)HKPGGEPK 46.159 0.032618 9640500.0 5326.6 8499.7 9617.9 9548.3 9932.2 10734.0 10236.0 18672.0 13201.0 12310.0 True False 7020.347999837251 11247.0618043073 9490.360361775778 7347.086954764441 8553.285472251504 10062.801283137318 11146.9841702405 15786.671439874917 13898.777909624354 11879.030646872385 0.5909866056020009 0.9467996285764718 0.7989170702471824 0.6184921289599371 0.7200322759082609 0.8471062650037645 0.9383748978857441 1.3289528337088152 1.1700262692127783 1.0 13.536129493633585 -7.449172733757212 2.507372500269912 1.1846794329005597 0.7528969217470625 0.68308221243956 0.12468583443909359 0.16182088211838264 1.997800517584614 0.06424538205867311 0.03703698981936984 3.5548989996546865e-08 7.449172733757212 -0.4317825111534972 AEVDNRS(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 1 AEVDNRSPQK 10 1 Q5W0B1 Q5W0B1 RNF219 RING finger protein 219 1 AEVDNRS(1)PQK 100.04 0.019993 3885100.0 17264.0 16763.0 16399.0 21960.0 18725.0 20979.0 18712.0 18271.0 17281.0 19846.0 True False 22753.592886492377 22181.31193166855 16181.53854508375 16897.461278617888 16125.356967027386 19667.179813577222 20377.331750052777 15447.636775811612 18194.43838013928 19151.19758065226 1.1881028740197157 1.158220619794425 0.8449361183256421 0.88231877967197 0.8420025379153433 1.0269425570255846 1.0640238901111456 0.8066146626474044 0.9500418082741959 1.0 14.225146990480178 -5.245047236753736 21.037062758849675 0.9240194393707845 1.1731624367179083 0.5960527729206792 0.08099066172443459 70.9222376962186 91014.60708041044 0.021491384160248875 0.05621806620842684 5.687910619837535e-06 5.245047236753736 0.24914299734712386 AEVDNRS(ph)PQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEVDNRSPQK 10 1 Q5W0B1 Q5W0B1 RNF219 RING finger protein 219 1 AEVDNRS(1)PQK 107.17 0.010673 3249100.0 10374.0 11404.0 11541.0 9258.2 12866.0 11208.0 12943.0 11789.0 9726.3 7971.2 True False 12130.11330416034 12536.113753589601 11816.181209486234 8739.493069489385 10344.999659353793 10620.232749443638 11716.945340794742 11479.551241477999 9868.5287371482 9416.315460015521 1.2882016703527417 1.3313183704201152 1.2548625053675462 0.9281223751051964 1.0986250092492909 1.1278543921494886 1.2443237899737303 1.219112856851875 1.0480244400320817 1.0 13.200946938192272 -5.541056615874272 24.997735962920263 1.1104264841206635 1.305592673082785 0.502467239487098 0.08970579304870549 203.44712748650707 279774.1122771333 0.025749955578846708 0.04460945276301298 2.8770233332744645e-06 5.541056615874272 0.19516618896212146 AEVLGHKT(ph)PEPAPR ddPTM_PC-9_AZD4547_30min_R2 1 AEVLGHKTPEPAPR 14 1 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;K7ENL0;K7ER34;K7EJ51 Q9UHD8 SEPT9 Septin-9 1 AEVLGHKT(1)PEPAPR 56.956 0.043011 11965000.0 50688.0 61861.0 63499.0 106280.0 102230.0 95116.0 94958.0 109610.0 96454.0 101600.0 True False 66805.72962410373 81856.35849221195 62656.961770490445 81778.78800963153 88037.12911824901 89168.38148377967 103409.07804197886 92672.29308722631 101552.36152525619 98043.01492463308 0.6813920367040747 0.8349025022857158 0.6390762444285873 0.8341113140237062 0.8979439196757084 0.9094822466682052 1.054731722820547 0.9452207600762246 1.0357939482309961 1.0 16.581127228808654 -6.415670649227405 1.1879807054075553 1.0028614770858877 0.7263664731456942 0.7900128910889087 0.06082225228975771 0.20259975003435013 0.5951370511428513 0.025459890554713947 0.03202668836498769 3.839983433846542e-07 6.415670649227405 -0.27649500394019344 AEVLGHKT(ph)PEPAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEVLGHKTPEPAPR 14 1 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;K7ENL0;K7ER34;K7EJ51 Q9UHD8 SEPT9 Septin-9 1 AEVLGHKT(1)PEPAPR 55.898999999999994 0.045495999999999995 8908900.0 30041.0 31810.0 31287.0 44758.0 42542.0 36069.0 42336.0 39191.0 36098.0 27349.0 True False 35126.34796320426 34967.886575033786 32033.000736608265 42250.35436739384 34206.20049030227 34177.47814415442 38325.62759390301 38162.27777629691 36625.86495929343 32307.15720543511 1.0872621116071106 1.082357273116901 0.9915140639863936 1.3077707239523373 1.0587808847677778 1.0578918450430748 1.1862890736624576 1.18123292413598 1.1336765016617363 1.0 14.979566189080074 AEVLGHKT(ph)PEPAPR ddPTM_PC-9_Lapatinib_30min_R1 1 AEVLGHKTPEPAPR 14 1 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;K7ENL0;K7ER34;K7EJ51 Q9UHD8 SEPT9 Septin-9 1 AEVLGHKT(1)PEPAPR 55.898999999999994 0.045495999999999995 8833200.0 64465.0 62021.0 64441.0 62818.0 55093.0 53004.0 49499.0 44424.0 52191.0 41034.0 True False 63545.71727856689 61877.394185058896 59142.9097294535 67437.84527470486 51852.538057005455 50737.14247835881 52061.81601953288 46488.10121778527 46312.69998440531 48126.67222563191 1.3203846087808853 1.2857193594221428 1.2289008775045622 1.401257185590072 1.0774178986219034 1.0542416529546912 1.0817663805104136 0.9659529543167966 0.9623083800034591 1.0 15.55454904948514 -6.403377463474416 4.720599499734195 1.0196046897447943 1.3006789747320433 0.8753542112383076 0.053076737456396274 0.08181211224794462 2.8088037891176385 0.01765689066979473 0.02000149343600019 3.9502313971260813e-07 6.403377463474416 0.28107428498724896 AEVPGAT(ph)GGDSPHLQPAEPPGEPR ddPTM_PC-9_Lapatinib_30min_R1 1 AEVPGATGGDSPHLQPAEPPGEPR 24 0 A0A0A0MQW0;Q9P2K5-2;A0A087WWC8;A0A0A0MR39;Q9P2K5-4;Q9P2K5 A0A0A0MQW0 MYEF2 Myelin expression factor 2 1 AEVPGAT(0.697)GGDS(0.303)PHLQPAEPPGEPR 85.76 4.4078999999999996e-05 7326900.0 13681.0 12997.0 14171.0 10861.0 13201.0 11414.0 12886.0 11967.0 12614.0 14795.0 True False 13485.906431211875 12966.906245033304 13005.915081641899 11659.754171233883 12424.543134164569 10925.849827333554 13553.174028317764 12523.030507681353 11193.27848869133 17352.29603690168 0.7771828236754676 0.7472732264051781 0.7495212768375611 0.6719430181710856 0.7160172410465064 0.6296486530715278 0.7810594055965482 0.721692995615662 0.6450603692380259 1.0 14.082838950819276 -11.461693045354945 2.9913926000110527 1.1864986940347755 0.7157456719187657 0.7480391766679221 0.049536260722341935 41729495.92896549 40596910.19873483 54645151.25439247 0.01244622573869093 3.453877694285474e-12 11.461693045354945 -0.4707530221160098 AEVPGATGGDS(ph)PHLQPAEPPGEPR ddPTM_PC-9_Lapatinib_30min_R1 2 AEVPGATGGDSPHLQPAEPPGEPR 24 0 A0A0A0MQW0;Q9P2K5-2;A0A087WWC8;A0A0A0MR39;Q9P2K5-4;Q9P2K5 A0A0A0MQW0 MYEF2 Myelin expression factor 2 1 AEVPGAT(0.244)GGDS(0.756)PHLQPAEPPGEPR;AEVPGAT(0.059)GGDS(0.941)PHLQPAEPPGEPR 101.08 1.8013e-06 20746900.0 30883.0 38716.0 37856.0 35351.0 43349.0 39652.0 39873.0 46349.0 44746.0 36146.0 True False 30442.60275675143 38626.35548070393 34743.62580838586 37950.83046747897 40799.297047413085 37956.17639332661 41937.42883991261 48502.54374534332 39706.234283730926 42393.78793848249 0.7180911222400462 0.9111324408367218 0.8195452092840169 0.8951979125467465 0.9623885722742406 0.8953240141787923 0.9892352365579574 1.1440955409723053 0.9366050125397742 1.0 15.371565258325365 -5.778530095749763 0.4636926954660191 1.0353508532628046 0.7235485455392928 0.5876931803680198 0.06889856881193562 1.4902633269891719 0.475603276447438 0.05582009363315386 0.23359048616416103 1.6652134277852142e-06 5.778530095749763 -0.3118023077235118 AEVSIQNNK ddPTM_PC-9_Lapatinib_30min_R1 1 AEVSIQNNK 9 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 159.28 0.00058007 6641400.0 32551.0 37280.0 30595.0 31151.0 29905.0 33527.0 34966.0 27305.0 30903.0 31970.0 False True 32086.8167708777 37193.68045047639 28079.59720011532 33441.948456689686 28146.046695492118 32093.12836525425 36776.368390048025 28573.689981803258 27422.378716983367 37495.97190265271 0.8557403673701727 0.9919380286244845 0.7488696992043774 0.8918810944149386 0.7506418761077875 0.8559086946345769 0.9808085115256401 0.7620469221597046 0.7313419902323782 1.0 15.194447998405876 -5.2538248303674076 24.980906085321383 0.8359208375808403 0.9238391858407993 0.10727106723542201 0.09589831952043801 1220.1909473189562 4003032.773936052 0.0238142102411917 0.06046160526236721 5.574105312240986e-06 5.2538248303674076 0.08791834825995892 AEVSQPR ddPTM_PC-9_Lapatinib_30min_R1 1 AEVSQPR 7 0 P22314;P22314-2;Q5JRR9;Q5JRS2;Q5JRS3;Q5JRS0;Q5JRS1 P22314;Q5JRS0 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 120.62 0.027533 1888600.0 8308.3 5343.3 7847.4 7019.3 8085.8 7653.5 8130.9 8687.4 10679.0 7796.4 False True 8189.822118444384 5330.927917141372 7202.217063840005 7535.522737698373 7610.209141294444 7326.177646179894 8551.878217200756 9091.048318912925 9476.218565144653 9143.997351950004 0.8956500973502428 0.5829975350992993 0.7876442639502839 0.8240950262405079 0.8322628330236259 0.8012007620078269 0.9352450452511367 0.9942094216567344 1.036332164195542 1.0 13.158609270418202 -7.3009634763650775 0.9214836824659199 1.0336557141441534 0.75736685320068 0.6392585056330846 0.0765206736172326 0.3573023877907827 0.5846928963728258 0.05864548876785333 0.03285490462456223 5.000765890383079e-08 7.3009634763650775 -0.2762888609434734 AEVVETTQVYTEEETRR ddPTM_PC-9_Lapatinib_30min_R1 2 AEVVETTQVYTEEETRR 17 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 195.28 2.5871e-12 8541900.0 24037.2 24163.0 24579.6 23054.0 28130.0 20862.5 23480.0 21057.7 23551.9 22753.1 False True 23694.425120117397 24107.052058070298 22558.76016799981 24749.46806588953 26475.44870570785 19970.259507862822 24695.67951147764 22036.11761691333 20899.237009498105 26685.943018399987 0.8878991124196011 0.9033614454414618 0.8453424393676296 0.9274346441055032 0.9921121650995433 0.7483437813718371 0.9254190303280623 0.8257575009329594 0.7831552737367407 1.0 14.703792373222713 -6.750618949197745 24.999814435278974 0.8499501902868565 0.9080326321120641 0.11519851870150166 0.0744206101193465 457.32964062171874 1056624.7940674177 0.023789742674813343 0.02356491443498938 1.775746841221787e-07 6.750618949197745 0.05808244182520761 AEVYGS(ph)ENESER ddPTM_PC-9_AZD4547_30min_R2 2 AEVYGSENESER 12 0 Q9BVS4;Q9BVS4-2 Q9BVS4 RIOK2 Serine/threonine-protein kinase RIO2 1 AEVYGS(1)ENESER;AEVYGS(0.999)ENES(0.001)ER 148.41 7.509199999999999e-05 21480800.0 31824.0 39112.0 36737.0 25828.0 33379.0 39827.0 39016.0 43693.0 37322.0 36336.0 True False 41943.37001967874 51754.189123153395 36249.843376470635 19873.753638622184 28744.9020134797 37336.61139402927 42488.34841599289 36941.25081525572 39294.764725626876 35063.88769981765 1.196198504249056 1.4759968879156131 1.0338227091874685 0.5667869407055378 0.8197865068347566 1.0648166487888746 1.2117409449783816 1.053541214012268 1.1206619488982459 1.0 15.097698342968654 -5.370929819628302 6.169567316473931 0.9730540607658479 1.3328609798016653 0.38235315569830197 0.1797816209050321 0.24386878674827872 11.705383933427193 0.052654384021121645 0.1113354752359227 4.25667193810298e-06 5.370929819628302 0.3598069190358174 AEVYGS(ph)ENESER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AEVYGSENESER 12 0 Q9BVS4;Q9BVS4-2 Q9BVS4 RIOK2 Serine/threonine-protein kinase RIO2 1 AEVYGS(0.999)ENES(0.001)ER 103.83 0.0019827 9607400.0 19151.0 33481.0 26844.0 13884.0 27967.0 15701.0 25431.0 13549.0 16197.0 15939.0 True False 22392.886050508467 36804.77241177952 27484.062766436902 13106.12449253532 22487.067112789333 14877.611919969191 23021.991575504228 13193.353106352146 16433.850483286493 18828.614526945417 1.1893007856983986 1.9547254716542541 1.4596965022096964 0.6960748213193962 1.1943028033532868 0.7901596741851615 1.2227129905154581 0.7007075899010672 0.8728125194643608 1.0 14.200639225033024 -5.639210996404721 5.777111524179699 0.9325963644436104 1.6024904628778054 0.5705746437650456 0.24267731024407885 0.13023849231646645 6.042060447032814 0.061985225919024854 0.10864267028091593 2.2950333646820745e-06 5.639210996404721 0.669894098434195 AEVYGS(ph)ENESER ddPTM_PC-9_Lapatinib_30min_R1 2 AEVYGSENESER 12 0 Q9BVS4;Q9BVS4-2 Q9BVS4 RIOK2 Serine/threonine-protein kinase RIO2 1 AEVYGS(1)ENESER;AEVYGS(0.761)ENES(0.239)ER 156.2 0.00035809 25002800.0 29302.3 42604.0 44669.0 36243.0 37940.0 43534.0 48072.0 43193.0 42025.0 34481.0 True False 28884.443828616295 42505.35305558193 40996.487247326404 38908.431123103735 35708.44379290994 41672.152302710594 50560.9329418975 45199.90446379887 37291.70195713122 40440.99490695552 0.7142367267440397 1.0510461761234107 1.0137358722664693 0.9621037072065654 0.8829763925211537 1.0304433013724725 1.2502395912421391 1.117675382808766 0.9221262247115822 1.0 15.30353086961122 -6.980712986508406 9.638879248948358 1.0905719140999908 0.9404778466335617 0.2592712694445244 0.11634370964238805 0.3799037372703506 177.05768920266232 0.04148067628827595 0.03623072849048077 1.0454108747855644e-07 6.980712986508406 -0.15009406746642906 AFAAVPTSHPPEDAPAQPPTPGPAAS(ph)PEQLSFR ddPTM_PC-9_AZD4547_30min_R2 3 AFAAVPTSHPPEDAPAQPPTPGPAASPEQLSFR 33 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 AFAAVPTSHPPEDAPAQPPT(0.067)PGPAAS(0.87)PEQLS(0.063)FR;AFAAVPTSHPPEDAPAQPPT(0.003)PGPAAS(0.975)PEQLS(0.022)FR;AFAAVPTSHPPEDAPAQPPT(0.083)PGPAAS(0.882)PEQLS(0.035)FR 144.89 7.286199999999999e-24 83239000.0 97706.0 144172.0 189939.0 203896.0 190585.0 148216.0 146994.0 206134.0 150128.0 133666.0 True False 128774.4755889498 190772.77956287758 187420.2847560622 156890.92736179754 164125.5624865642 138948.03008957327 160076.1812348896 174280.72678808792 158063.4595876135 128986.39402476375 0.9983570481412694 1.4790147519454775 1.4530236787616522 1.2163370295604703 1.2724253881774086 1.077230130667092 1.2410315246440413 1.3511558959825503 1.2254273854439819 1.0 16.976859367153182 -5.944259273478993 24.999609284151937 1.2118173810843533 1.3282972880443684 0.09361317490696852 0.15304919795951175 200.5718743720419 89954.27842514863 0.04259704352041335 0.06318161867311523 1.1369483258790418e-06 5.944259273478993 0.11647990696001509 AFAAVPTSHPPEDAPAQPPTPGPAAS(ph)PEQLSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AFAAVPTSHPPEDAPAQPPTPGPAASPEQLSFR 33 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 AFAAVPTSHPPEDAPAQPPTPGPAAS(0.924)PEQLS(0.075)FR;AFAAVPTSHPPEDAPAQPPT(0.052)PGPAAS(0.878)PEQLS(0.07)FR 145.12 3.4336e-21 52378000.0 122938.0 140595.0 166784.0 142635.0 269580.0 157100.0 181547.0 135354.0 134997.0 143654.0 True False 143748.9752638199 154552.34244001473 170760.7630918421 134643.62337890954 216757.7341962221 148861.3994412559 164349.55387354273 131801.1009194178 136971.07573576717 169697.33303556137 0.847090361954576 0.9107529250776564 1.0062666279855905 0.793433938945251 1.2773196273555982 0.8772170827815005 0.9684863688405876 0.7766833960307312 0.8071492538251255 1.0 17.372604366090492 -7.74238046910211 24.880033342320196 0.8439372382730378 0.9579496781232096 0.08603716598987066 0.1351943973724178 455.81459295649313 595034.3236176276 0.06229320838412395 0.03588972568618507 1.8097539404064216e-08 7.74238046910211 0.11401243985017184 AFAAVPTSHPPEDAPAQPPTPGPAAS(ph)PEQLSFR ddPTM_PC-9_Lapatinib_30min_R1 2 AFAAVPTSHPPEDAPAQPPTPGPAASPEQLSFR 33 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 AFAAVPTSHPPEDAPAQPPT(0.003)PGPAAS(0.943)PEQLS(0.054)FR;AFAAVPTSHPPEDAPAQPPT(0.034)PGPAAS(0.95)PEQLS(0.017)FR 133.13 5.192e-22 59053000.0 238504.0 248811.0 144576.0 91292.0 133610.0 101792.0 82431.0 88684.0 163086.0 62834.0 True False 235102.88922372356 248234.893416402 132689.51935949895 98005.91822118463 125751.32248736694 97438.5934487415 86698.87384201928 92804.58239685933 144717.53730828542 73694.77317895768 3.190224748406625 3.3684192610729324 1.8005282279284665 1.3298896786504881 1.7063804807702854 1.3221913745785634 1.176458927846659 1.2593102386175488 1.9637422176042074 1.0 16.16927467897557 -5.342266413046781 3.5048899022077866 1.4129348643201982 3.3066672228617136 0.8869743013951913 0.264661407399613 0.06716399006131983 1.5691860141122878 0.06997083064376301 0.1695690197230531 4.5470903845142565e-06 5.342266413046781 1.8937323585415153 AFAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 AFASPR 6 0 M0R1U9;M0R364;Q8TBC5-2;Q8TBC5;M0R3C6;Q8TBC5-3 M0R1U9 ZSCAN18 Zinc finger and SCAN domain-containing protein 18 1 AFAS(1)PR 95.352 0.034483 2168700.0 20359.0 17566.0 19167.0 15810.0 15484.0 17045.0 15918.0 17402.0 16420.0 14547.0 True False 20068.676926616663 17525.32700625183 17591.16324675961 16972.720140613925 14573.261562715275 16316.025083835675 16742.156152627824 18210.560449124347 14570.606689734544 17061.42956734091 1.176259987324406 1.0271898340687065 1.0310486103950351 0.9948005865289979 0.8541641546035216 0.9563105494435183 0.9812868310095045 1.0673525554964696 0.8540085478901303 1.0 14.058450913855479 -3.977483581627532 0.8881190548942183 0.9594113113310134 1.8210120071679674 0.5173726905786122 0.06284887910171146 6.577490331925171 1.4339478106376602 0.02158489780606219 7.7389197241473955 0.00010532135027972912 3.977483581627532 0.861600695836954 AFCGFEDPR ddPTM_PC-9_AZD4547_30min_R2 1 AFCGFEDPR 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 98.41799999999999 0.020589 3615500.0 22398.0 24136.0 49087.0 59789.0 49846.0 43237.0 31537.0 51609.0 33148.0 36409.0 False True 29520.098092658525 31937.489994795236 48436.07430712396 46005.56978084179 42925.743304589974 40533.383554966305 34343.73190473569 43634.01490683936 34900.13560701675 35134.331992037114 0.8402066132735637 0.9090108786480866 1.3785967047303354 1.3094192253681824 1.2217606218987944 1.1536688263819228 0.9774977908365923 1.2419195821548172 0.9933342582100767 1.0 15.10059384845596 -10.543175363783773 14.629472786132789 0.9999999834252836 1.1255328568953848 0.034953732716765495 0.17004013514023997 0.0 0.0 0.1747557495632339 0.042384494949011815 2.863021676851199e-11 10.543175363783773 0.12553287347010122 AFEDDDITHVEGSVDPIR ddPTM_PC-9_AZD4547_30min_R2 1 AFEDDDITHVEGSVDPIR 18 0 J3KQ32;Q9NTK5;Q9NTK5-3 J3KQ32 OLA1 Obg-like ATPase 1 0 96.096 0.0025578000000000003 0.0 5954.6 7931.5 7876.2 5664.4 7932.5 11931.0 6940.2 9610.7 9088.7 7124.8 False True 7848.038936625788 10495.2022660639 7771.7564417823405 4358.560094107611 6831.209299916946 11184.95268391199 7557.864355051101 8125.587146915474 9569.110127051199 6875.362920620339 1.1414726796585872 1.5264942937902333 1.130377629735526 0.6339389126696972 0.9935779941781737 1.6268163314501531 1.0992676957290253 1.1818411974363576 1.391797093118077 1.0 12.747220153817306 AFEDDDITHVEGSVDPIR ddPTM_PC-9_Lapatinib_30min_R1 2 AFEDDDITHVEGSVDPIR 18 0 J3KQ32;Q9NTK5;Q9NTK5-3 J3KQ32 OLA1 Obg-like ATPase 1 0 ; 139.88 3.8038000000000004e-05 6542800.0 25683.0 31778.0 25637.0 27148.0 33149.0 30245.0 30538.0 30338.0 30883.0 29061.0 False True 25316.75571031463 31704.419993434494 23529.22482168186 29144.554483073178 31199.240993441534 28951.491854538574 32119.108216418426 31747.614234314107 27404.6313275927 34084.155128651546 0.7427719893527025 0.9301806036783169 0.6903273598207196 0.8550763360002994 0.9153590832948381 0.8494120433750052 0.9423472019530483 0.931447885813273 0.8040284766969635 1.0 15.056813601794286 -5.995945571146295 24.989077188060843 0.900973944872756 0.7971186730685773 0.33132095830055897 0.07534850811997439 147.89806698144434 911535.6171473452 0.020118895445694042 0.029695267224838093 1.0093793807073652e-06 5.995945571146295 -0.10385527180417864 AFFESHPAPSAER ddPTM_PC-9_Lapatinib_30min_R1 1 AFFESHPAPSAER 13 0 E9PLK3;P55786-2;P55786;H0YDG0 E9PLK3 NPEPPS Puromycin-sensitive aminopeptidase 0 81.23899999999999 0.009951799999999998 3219300.0 16743.0 17648.0 19814.0 15179.0 19921.0 19899.0 17440.0 13993.0 19872.0 16008.0 False True 16504.24174970985 17607.137140289884 18184.969404251828 16295.314295659631 18749.285946192897 19047.96615683462 18342.957865424625 14643.16586395798 17633.806098563036 18774.96147068078 0.8790559584094532 0.9377988427718168 0.9685755910950714 0.867927975304056 0.9986324592714622 1.014540891952304 0.9769904398509272 0.7799305413662199 0.9392192961940409 1.0 14.196522326643734 -1.5361900684296343 24.95202571034943 0.9342336865119326 0.004677263551401967 0.0 0.07015498542308125 0.0 0.0 0.01645152467273065 0.0 0.029094435251220605 1.5361900684296343 -0.9295564229605306 AFFSEVER ddPTM_PC-9_AZD4547_30min_R2 3 AFFSEVER 8 0 Q9UQ80;Q9UQ80-2;F8VR77 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 0 ;; 157.33 0.00018136 14608700.0 50023.0 39625.4 57262.0 82487.0 78498.0 60340.0 46351.0 62422.0 42858.0 61498.0 False True 65929.27345696294 52433.5356330692 56502.66846567386 63470.89656144601 67599.9076741105 56566.93026127313 50476.14920621506 52776.114214860296 45123.38638365888 59344.973738534354 1.1109495767482869 0.8835379364069486 0.9521053748311812 1.0695243853521597 1.1391008103221383 0.9531882263609908 0.8505547483870479 0.8893106002099599 0.7603573401593571 1.0 15.8568382245883 -7.038014816085961 5.27857989244787 0.8689472285962107 1.0230917243198436 0.4075097982627144 0.08818027407874154 0.2107571453346661 15.040727329492231 0.034540989246802135 0.02745182272812454 9.161892335194985e-08 7.038014816085961 0.15414449572363298 AFFSEVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AFFSEVER 8 0 Q9UQ80;Q9UQ80-2;F8VR77 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 0 ; 113.41 0.017113999999999997 8919800.0 31791.0 29602.0 30906.0 39021.0 41677.0 39445.0 36346.0 37279.0 30878.0 27665.0 False True 37172.58839912871 32540.690927197422 31642.91625165771 36834.77987778891 33510.69103084779 37376.43476104606 32903.04375774751 36300.46575036548 31329.53233456321 32680.445503980493 1.1374565990724048 0.9957236024592734 0.9682522916587409 1.1271198819276322 1.0254049635512519 1.1436941628134658 1.006811359219075 1.1107702233111867 0.9586629512363061 1.0 14.996140030168984 -8.274842357806392 24.869381365785806 0.9793314657185995 1.0604235178613268 0.23401728990761728 0.061227320373940075 1244.8703993498532 2309845.9432093105 0.055404261081976665 0.014666155799564647 5.310771820683717e-09 8.274842357806392 0.0810920521427273 AFFSEVER ddPTM_PC-9_Lapatinib_30min_R1 4 AFFSEVER 8 0 Q9UQ80;Q9UQ80-2;F8VR77 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 0 ;;; 171.38 0.00018136 35028900.0 131695.0 108544.0 129906.0 104832.0 117929.0 140262.0 111955.0 114582.0 118108.0 100995.0 False True 129817.00515009485 108292.67303692372 119225.63013166124 112541.6949893002 110992.64807733468 134263.3212266915 117751.48209997785 119905.89802215643 104805.4333076228 118451.85118262153 1.0959474575872288 0.9142336903622128 1.0065324344137665 0.9501049908944907 0.9370275514412458 1.133484364205443 0.9940873099436505 1.012275425204568 0.8847935448981752 1.0 16.853941219837402 -8.223435548901836 24.781803815939124 0.9423966531570734 1.0022183411776848 0.11666343345517383 0.06895287709708438 982.2540303582444 640516.6211811416 0.04559236627540873 0.017231516655759626 5.978117558442133e-09 8.223435548901836 0.059821688020611385 AFGPGLQGGSAGS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 7 AFGPGLQGGSAGSPAR 16 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 AFGPGLQGGSAGS(1)PAR;AFGPGLQGGSAGS(1)PAR;AFGPGLQGGS(0.003)AGS(0.997)PAR;AFGPGLQGGS(0.115)AGS(0.885)PAR;AFGPGLQGGS(0.003)AGS(0.997)PAR;AFGPGLQGGSAGS(1)PAR;AFGPGLQGGSAGS(1)PAR 234.82 5.9623999999999996e-37 960832000.0 95133.0 90192.2 135564.0 198630.0 142850.7 136630.0 114885.5 153849.0 113154.5 132787.7 True False 125383.31511067407 119345.06484539986 133766.332784056 152838.92230290864 123018.34608756934 128086.50450112269 125110.08693729596 130075.17214831401 119135.61586050967 128138.8430404304 0.9784957639356326 0.9313730482781406 1.0439171262210476 1.1927602799932013 0.9600394631997307 0.9995915482139074 0.9763634817416074 1.0151111798884642 0.9297385010954092 1.0 16.967348344084954 AFGPGLQGGSAGS(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 AFGPGLQGGSAGSPAR 16 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 AFGPGLQGGS(0.025)AGS(0.975)PAR;AFGPGLQGGS(0.299)AGS(0.701)PAR;AFGPGLQGGS(0.006)AGS(0.994)PAR;AFGPGLQGGSAGS(1)PAR;AFGPGLQGGS(0.006)AGS(0.994)PAR;AFGPGLQGGSAGS(1)PAR;AFGPGLQGGS(0.005)AGS(0.995)PAR;AFGPGLQGGSAGS(1)PAR 167.18 3.0585e-05 551654200.0 176352.6 218928.0 187192.0 205619.0 198265.0 168195.0 210438.5 149105.2 151055.4 134374.0 True False 206205.6120573806 240661.7249952531 191655.36720961292 194098.83405579202 159416.396507211 159374.55810962452 190504.24183719663 145191.34649001827 153264.29945625958 158734.94249600123 1.2990562053630708 1.516123174967073 1.2073924253599109 1.2227858025694731 1.0042930308884381 1.0040294569271628 1.2001405540685897 0.9146779165757777 0.9655359875165517 1.0 17.27626021960257 -5.825545956033493 1.3322442196528834 1.0148039974286007 1.4079764684008786 0.7161912499751222 0.0951583168423883 0.23705604685109416 0.8469758645722159 0.032743153263478375 0.07419621559449348 1.494355904728299e-06 5.825545956033493 0.3931724709722779 AFGPGLQGGSAGS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 6 AFGPGLQGGSAGSPAR 16 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 AFGPGLQGGSAGS(1)PAR;AFGPGLQGGSAGS(1)PAR;AFGPGLQGGS(0.001)AGS(0.999)PAR;AFGPGLQGGSAGS(1)PAR;AFGPGLQGGS(0.054)AGS(0.946)PAR;AFGPGLQGGSAGS(1)PAR 208.07 3.9969e-17 816005000.0 189737.0 216058.0 217774.0 171599.0 183322.0 180179.0 163952.0 160721.0 179015.0 119356.0 True False 187031.31558649562 215557.73097556384 199869.4623519501 184218.96289748338 172539.36038491916 172473.16418776338 172440.6323367029 168188.68440085725 158852.44558847917 139986.5255681267 1.3360665594594947 1.5398462823527912 1.4277764344874777 1.3159763923694945 1.2325426299758406 1.2320697544838095 1.2318373617522345 1.2014633816953013 1.1347695425955198 1.0 17.09492844138142 -6.490671227842624 0.2329634939935641 0.9695816527793492 1.6289009802819936 0.8184430829623268 0.06088010759487794 1.9589696816287672 0.20623625845255283 0.13410768298450676 0.397103692542255 3.23093910061866e-07 6.490671227842624 0.6593193275026444 AFGPGLQGGSAGSPAR ddPTM_PC-9_Lapatinib_30min_R1 2 AFGPGLQGGSAGSPAR 16 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 240.18 8.739899999999999e-37 19573500.0 14140.7 13899.099999999999 16210.0 9956.1 14906.2 14935.2 15198.9 13936.5 12607.8 10334.0 False True 13939.051024913215 13866.917487908153 14877.27637240952 10688.304806575981 14029.446622716765 14296.456311651653 15985.824673211142 14584.040667694586 11187.776797980216 12120.218130810554 1.150066019808591 1.144114514957231 1.2274759589177942 0.8818574625654191 1.15752426823514 1.1795543741336576 1.318938694063097 1.2032820292747703 0.9230672812348155 1.0 13.565128043162854 -8.262905226511728 24.97898098074759 0.9615336238661734 1.1565968428131597 0.35355676471755115 0.1061723407188291 156.26174460654164 2662658.606692183 0.09128809284086123 0.028367616404355832 5.458769715622875e-09 8.262905226511728 0.1950632189469863 AFGSGIDIKPGT(ph)PPIAGR ddPTM_PC-9_AZD4547_30min_R2 1 AFGSGIDIKPGTPPIAGR 18 1 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3;H7C5N8;A0A2R8Y7F4;A0A2R8YET2;A0A2R8Y424 E7EPN9 PRRC2C Protein PRRC2C 1 AFGS(0.001)GIDIKPGT(0.999)PPIAGR 83.25200000000001 0.023739 8270600.0 13049.0 12060.0 16651.0 23148.0 20882.0 18498.0 16952.0 20074.0 16419.0 22515.0 True False 17198.310563938776 15958.159153846147 16430.19686042988 17811.58623303492 17982.894749557603 17341.31713578107 18460.69515962455 16972.024554629865 17286.87481994715 21726.756703032643 0.7915728426018697 0.7344933885883985 0.7562194894066512 0.8197995898094058 0.827684269463354 0.798154891353874 0.8496756056115723 0.7811577579943578 0.7956491185605364 1.0 14.407185209490972 -14.522878745222961 0.22917406232411458 2.0867464942218716 0.7723466929276475 0.8024079900963746 0.03076410125063688 74.01254773638898 0.7388982978002973 37.33131799793127 0.05848879596087353 3.000000000396343e-15 14.522878745222961 -1.3143998012942242 AFGSGIDIKPGT(ph)PPIAGR ddPTM_PC-9_Lapatinib_30min_R1 1 AFGSGIDIKPGTPPIAGR 18 1 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3;H7C5N8;A0A2R8Y7F4;A0A2R8YET2;A0A2R8Y424 E7EPN9 PRRC2C Protein PRRC2C 1 AFGSGIDIKPGT(1)PPIAGR 87.669 0.01668 106570000.0 15523.0 14687.0 11755.0 10409.0 13853.0 10493.0 8049.9 9195.8 12784.0 16419.0 True False 15301.639173430434 14652.993153866595 10788.54927561221 11174.512583406091 13038.193776045904 10044.238850377686 8466.684433536791 9623.070438918381 11344.131298511962 19257.002273057704 0.7946013069146706 0.7609176623698832 0.5602403283041811 0.5802830796276246 0.6770624830993307 0.5215889112933475 0.43966783165323986 0.49971798842138226 0.5890912374447519 1.0 14.233095516666637 -10.618767897339891 5.101186144838964 1.0000098382696412 0.5973232580040306 0.5547567391390928 0.1067197697885923 168820473.69731835 13.775293427084573 19508.87109597939 0.028728744329778302 2.405648121775969e-11 10.618767897339891 -0.40268658026561055 AFGYYGPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AFGYYGPLR 9 0 A0A087X2D0;P84103-2;P84103 A0A087X2D0 SRSF3 Serine/arginine-rich splicing factor 3 0 101.21 0.016454 2030700.0 19960.0 14658.0 15946.0 16662.0 21789.0 23209.0 21637.0 19685.0 19022.0 15311.0 False True 23338.83377203013 16113.149368652796 16326.21311554177 15728.482158932846 17519.601863645254 21991.879182890556 19587.38672168553 19168.289607981555 19300.160763911565 18086.76309819069 1.2903820128193546 0.8908807662917128 0.9026608590442013 0.8696128806213116 0.9686421925545 1.21591016941503 1.0829680587592234 1.0597965763093924 1.0670876076130094 1.0 14.142646618352456 -6.6166271703617845 24.99999992964942 1.0891477326255097 0.9682557622510806 0.1384337440583171 0.12214241993884986 28.681566078023277 7632.9804951746 0.04042763916401753 0.04042763736425046 2.417535330179949e-07 6.6166271703617845 -0.12089197037442911 AFGYYGPLR ddPTM_PC-9_Lapatinib_30min_R1 2 AFGYYGPLR 9 0 A0A087X2D0;P84103-2;P84103 A0A087X2D0 SRSF3 Serine/arginine-rich splicing factor 3 0 ; 114.59 0.0093543 14192500.0 69718.0 74073.0 75263.0 68233.0 74401.0 66548.0 60175.0 46180.0 69538.0 54074.0 False True 68723.80853528448 73901.48851953172 69075.16666358172 73251.08243861524 70024.87945799397 63701.897170964934 63290.567061463706 48325.69138837845 61705.89817239715 63420.618850924075 1.0836193304393014 1.1652596562206983 1.0891594550023105 1.1550042204854318 1.1041342819847566 1.0044351241778644 0.9979493768459423 0.7619870676754571 0.9729627255363508 1.0 15.95266433470806 -7.0568469825428135 1.7054414256675448 0.9054637681478114 1.124735674956121 0.6300787266204411 0.06754650676907491 0.21186634937848417 1.2317573622807032 0.031534329823289645 0.022833589125292108 8.773098742978195e-08 7.0568469825428135 0.21927190680830966 AFHAALRNS(ph)PVNTK ddPTM_PC-9_AZD4547_30min_R2 2 AFHAALRNSPVNTK 14 1 Q9BPX5 Q9BPX5 ARPC5L Actin-related protein 2/3 complex subunit 5-like protein 1 AFHAALRNS(0.929)PVNT(0.071)K;AFHAALRNS(0.91)PVNT(0.09)K 74.726 0.0086435 180372000.0 189548.0 148627.0 250561.0 365480.0 297740.0 272044.0 191733.0 265907.0 203400.0 260476.0 True False 249820.32115667665 196667.7711906043 247238.39742635097 281224.23260971176 256403.9403665007 255033.04567447444 208796.86556396243 224817.1830849839 214151.30875066985 251356.81452272367 0.9938872022667676 0.7824246641732673 0.9836152558497658 1.1188247796014616 1.0200795266018967 1.0146255479833766 0.8306791521066414 0.8944145139325814 0.8519813125309548 1.0 17.93937727683739 -7.252723041376331 24.849346736171256 0.8854699530580917 0.983877962967147 0.20052313309809366 0.08858383542902762 999.078744252595 2848272.92360901 0.03682041292642643 0.02807638581488228 5.588264563808653e-08 7.252723041376331 0.0984080099090553 AFHAALRNS(ph)PVNTK ddPTM_PC-9_Lapatinib_30min_R1 1 AFHAALRNSPVNTK 14 1 Q9BPX5 Q9BPX5 ARPC5L Actin-related protein 2/3 complex subunit 5-like protein 1 AFHAALRNS(0.975)PVNT(0.025)K 77.051 0.007352199999999999 66347000.0 177700.0 112340.0 156910.0 115960.0 128570.0 118200.0 99875.0 97356.0 158320.0 110950.0 True False 175165.96541381135 112079.88363214917 144009.46549011604 124488.08523121997 121007.76537834547 113144.86153765787 105046.03880787182 101879.51517555183 140488.33441649034 130127.55966841774 1.3461096623970927 0.8613078114870021 1.1066792142807507 0.9566619519218842 0.929916504134015 0.8694919187446991 0.8072543516188503 0.7829203547285012 1.0796201417629996 1.0 16.989567016709728 AFHNEAQVNPER ddPTM_PC-9_AZD4547_30min_R2 2 AFHNEAQVNPER 12 0 P17987;F5H282;E7EQR6 P17987 TCP1 T-complex protein 1 subunit alpha 0 ; 91.09299999999999 0.0055324 9934500.0 35511.0 35906.0 47786.0 59781.0 59780.0 46110.0 34485.0 54919.0 42846.0 42134.0 False True 46802.7593253146 47511.912319900446 47152.326417182274 45999.41405724297 51480.57887791177 43226.73441079389 37554.098193702936 46432.5304630725 45110.75208815738 40658.9014845915 1.1511073249987198 1.168548843797613 1.1597048787717883 1.1313491603966566 1.2661576431773829 1.063155491969588 0.9236377969516665 1.14200159787074 1.1094926434560215 1.0 15.31128361676502 -6.910117548019897 9.3883546977208 1.046805772972022 1.171472516309699 0.4967500342375526 0.0644173806462618 0.2794797369298347 26.58477144494745 0.02315018943201531 0.020418803350612847 1.229935826014344e-07 6.910117548019897 0.12466674333767713 AFHNEAQVNPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AFHNEAQVNPER 12 0 P17987;F5H282;E7EQR6 P17987 TCP1 T-complex protein 1 subunit alpha 0 ;; 143.55 7.1855e-05 11212300.0 48434.0 64627.0 57148.0 61281.0 74626.0 64876.0 53826.0 52378.0 52596.0 45177.0 False True 56632.91958489513 71042.74145503645 58510.625054996875 57847.6242456826 60003.571007223385 61473.78835232924 48727.211613506755 51003.132999078334 53365.116998143814 53367.23247906476 1.0611927385800164 1.3312052762508446 1.0963773524877798 1.0839539837179197 1.1243523079590452 1.1519013727467424 0.913054871875205 0.9557012914073475 0.9999603599283179 1.0 15.70366657745515 -7.252943193731662 24.856966464675327 0.9634875708991801 1.1446744633899502 0.5763799720346406 0.07315412382845851 416.7380466411478 1219236.7641117128 0.028496799680255615 0.021703924673729155 5.5854324812332994e-08 7.252943193731662 0.18118689249077002 AFHNEAQVNPER ddPTM_PC-9_Lapatinib_30min_R1 2 AFHNEAQVNPER 12 0 P17987;F5H282;E7EQR6 P17987 TCP1 T-complex protein 1 subunit alpha 0 ; 168.98 0.0001833 14376100.0 66864.0 71743.0 72968.0 70657.0 79057.0 71417.0 74796.0 78526.0 72992.0 65174.0 False True 65910.50709864407 71576.88349137676 66968.85270462553 75853.35148484228 74407.02269204214 68362.66139115824 78668.57090036117 82174.60463325717 64770.87232016463 76439.23906110378 0.86226011546186 0.9363892729774539 0.8761056955458721 0.9923352510640097 0.9734139639009601 0.8943398996490622 1.0291647570886375 1.075031693703396 0.8473510871607222 1.0 16.22202579616628 -5.108558349927164 0.6043976639895339 0.9824953807783482 0.8317081736932788 0.21351546845241176 0.064988286743599 4.125013959947322 1.4980220077564235 0.034720220064373884 0.4101732760300465 7.788281675416848e-06 5.108558349927164 -0.15078720708506943 AFHPTYEEK ddPTM_PC-9_Lapatinib_30min_R1 1 AFHPTYEEK 9 0 Q9H3P7 Q9H3P7 ACBD3 Golgi resident protein GCP60 0 101.46 0.0029303000000000003 1965100.0 28285.0 29088.0 35895.0 29187.0 30735.0 27434.0 27176.0 24607.0 40830.0 26292.0 False True 27881.65071316627 29020.648523161406 32943.851658706946 31333.50934497775 28927.22772733493 26260.711771777515 28583.040306810748 25750.331052270005 36231.29544103908 30836.53716811213 0.9041758016201155 0.941112433116241 1.0683382339302994 1.0161163419276382 0.9380828842626465 0.8516102709137378 0.9269212087915076 0.8350591025148655 1.1749469547607194 1.0 14.912353144449371 -8.265453497309487 24.999908110650342 1.0874734690237773 0.9395476737770941 0.38994606390357023 0.07603883470674065 403.9820352023498 2515945.4999950263 0.06803566205597779 0.020089746317911748 5.426833567993461e-09 8.265453497309487 -0.14792579524668314 AFITNIPFDVK ddPTM_PC-9_Lapatinib_30min_R1 1 AFITNIPFDVK 11 0 A0A087X0X3;P52272-2;P52272;M0R2T0;M0R019;M0QYQ7;M0R0N3;M0R0Y6 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 138.71 0.00018128 0.0 30186.0 31717.0 28995.0 26779.0 29163.0 29927.0 31081.0 32067.0 27870.0 32683.0 False True 29755.542104565568 31643.561235186673 26611.14302393671 28748.416992125254 27447.689676664024 28647.09197324438 32690.222099499006 33556.94988633892 24730.987115889264 38332.21300263991 0.7762542199824551 0.8255083324567618 0.6942240204629986 0.749980623089655 0.7160476144378547 0.747337284473283 0.852813326933346 0.8754242778528827 0.6451750415293284 1.0 15.226269670037786 -7.25408472169985 24.06395836056771 0.8329718522958958 0.7506280342889944 0.2065395473226349 0.08718610277707033 606.6994714487025 1985085.8004450856 0.032545536311387784 0.024664924029329075 5.570770643374278e-08 7.25408472169985 -0.08234381800690138 AFKPEETSSNSDPPS(ph)PPVLNNSHPVPR ddPTM_PC-9_AZD4547_30min_R2 3 AFKPEETSSNSDPPSPPVLNNSHPVPR 27 1 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 AFKPEETSSNSDPPS(1)PPVLNNSHPVPR;AFKPEETSSNSDPPS(1)PPVLNNSHPVPR;AFKPEETSSNSDPPS(0.999)PPVLNNS(0.001)HPVPR 114.19 3.5495e-12 27644500.0 103416.6 113158.3 150076.1 177927.0 161832.5 154218.6 114884.6 146453.0 123253.6 147954.0 True False 136300.92760109075 149734.50754383657 148085.99285601813 136908.67909474697 139364.8508072875 144575.2865626642 125109.10683904 123822.05400514137 129768.53366878863 142774.1754936925 0.9546609331119006 1.0487506373339313 1.0372043287517376 0.9589176657566854 0.9761208588694975 1.0126151039762177 0.8762726621003466 0.8672580568368373 0.908907603353812 1.0 17.123375527638352 -7.256936450137079 24.946133247429874 0.9020477505055667 0.999354642268143 0.4600095866290451 0.044426646551568624 297.859802307182 1650141.7217986179 0.01723663416760193 0.012892728345355844 5.5343108629012175e-08 7.256936450137079 0.09730689176257623 AFKPEETSSNSDPPS(ph)PPVLNNSHPVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AFKPEETSSNSDPPSPPVLNNSHPVPR 27 1 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 AFKPEETSS(0.001)NS(0.001)DPPS(0.996)PPVLNNSHPVPR;AFKPEETSSNS(0.001)DPPS(0.998)PPVLNNSHPVPR 74.278 2.5084000000000002e-05 15459100.0 113857.0 118255.0 119579.0 133630.0 160137.0 133295.0 134590.0 120297.0 126047.0 105553.0 True False 133130.74132174486 129994.57487993177 122430.21686588292 126143.1443343051 128759.30440307329 126304.77554756339 121840.66085278252 117139.3312152071 127890.19891750367 124688.92334291196 1.0677030304898594 1.0425511055414964 0.9818852676206267 1.0116627921102008 1.0326442874878885 1.0129590677449962 0.9771570528177845 0.9394525838759356 1.0256740974961165 1.0 16.927973784447808 -7.144103193948128 3.9686316024621564 0.9806338850276936 1.0245709847869524 0.3082066059728137 0.028930135254703598 0.2940984179627955 8.032398714279788 0.011897095717380839 0.009045822546651818 7.176237543881854e-08 7.144103193948128 0.04393709975925886 AFKQS(ph)PPAVPALGAGVK ddPTM_PC-9_AZD4547_30min_R2 2 AFKQSPPAVPALGAGVK 17 1 A0A0C4DFW9;O15350-12;O15350-4;O15350-10;O15350-9;O15350-3;O15350-2;O15350-6;O15350-5;O15350-13;O15350-11;O15350-8;O15350 A0A0C4DFW9 TP73 Cellular tumor antigen p53;Tumor protein p73 1 AFKQS(1)PPAVPALGAGVK;AFKQS(1)PPAVPALGAGVK 72.383 0.020455 4886500.0 89651.0 74332.0 97567.0 100896.0 96157.0 97605.0 90719.0 104368.0 81995.0 87423.0 True False 118158.15314335756 98358.3653585151 96273.19783085464 77635.98602766082 82807.26034063818 91501.74392031088 98792.81525400997 88240.32373804957 86329.08830388979 84362.34737949018 1.400602956338359 1.16590361000822 1.1411868069268563 0.9202682054166662 0.9815665745779134 1.084627760637163 1.1710534180563599 1.0459680945234364 1.023313018016824 1.0 16.364311618180743 -4.712800256935821 1.4762056522960574 1.043440754297263 1.5798667232777444 0.7235004697087035 0.06782784345583394 0.7909024104030661 1.4183208559642377 0.021204130705800992 0.6571868215352554 1.9373127784352356e-05 4.712800256935821 0.5364259689804813 AFKQS(ph)PPAVPALGAGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AFKQSPPAVPALGAGVK 17 1 A0A0C4DFW9;O15350-12;O15350-4;O15350-10;O15350-9;O15350-3;O15350-2;O15350-6;O15350-5;O15350-13;O15350-11;O15350-8;O15350 A0A0C4DFW9 TP73 Cellular tumor antigen p53;Tumor protein p73 1 AFKQS(1)PPAVPALGAGVK 79.695 0.0029363 4438300.0 78648.0 89454.0 80484.0 89269.0 91625.0 82668.0 91349.0 73625.0 69310.0 72865.0 True False 91961.55303119367 98334.40193910965 82403.04379726974 84267.54734400292 73671.73898556604 78332.74455130324 82695.76141051202 71692.4217621356 70323.52762836231 86074.84770097742 1.0683905401804086 1.1424289971528234 0.9573417322042385 0.9790031535896173 0.8559032162508197 0.9100538269138725 0.960742465647987 0.8329079130200017 0.8170043805673065 1.0 16.39330410267268 -5.54086391915148 1.501174323856697 0.8937172439027397 1.113272902221828 0.6132919997045261 0.061039612916474036 0.2812074769926089 1.1994583636873133 0.018921418724107526 0.05923800665048339 2.878300153499594e-06 5.54086391915148 0.2195556583190883 AFKQS(ph)PPAVPALGAGVK ddPTM_PC-9_Lapatinib_30min_R1 1 AFKQSPPAVPALGAGVK 17 1 A0A0C4DFW9;O15350-12;O15350-4;O15350-10;O15350-9;O15350-3;O15350-2;O15350-6;O15350-5;O15350-13;O15350-11;O15350-8;O15350 A0A0C4DFW9 TP73 Cellular tumor antigen p53;Tumor protein p73 1 AFKQS(1)PPAVPALGAGVK 80.236 0.0027719000000000003 5083200.0 49927.0 39494.0 43753.0 41637.0 52764.0 54021.0 38409.0 38568.0 47771.0 35696.0 True False 49215.03182450956 39402.55406950411 40155.79723146416 44699.123876960264 49660.52525801527 51710.64775910161 40397.63008331965 40360.01007940625 42390.52692906877 41866.006038069805 1.1755368252648009 0.9411586582602216 0.959150418956838 1.0676710798807565 1.1861777598956469 1.2351464267233856 0.9649267724889993 0.964028191337523 1.0125285629233896 1.0 15.353491672982134 AFLAELEQNS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 AFLAELEQNSPK 12 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 AFLAELEQNS(1)PK;AFLAELEQNS(1)PK;AFLAELEQNS(1)PK 165.64 0.00083449 20986000.0 224229.0 199769.0 193282.0 231119.0 237867.0 219363.0 216918.0 222934.0 174888.0 211386.0 True False 295529.15774706367 264340.42255428596 190718.95439178453 177838.085302955 204843.27293329223 205646.19693244426 236223.2817741531 188484.67281368235 184132.22263907158 203985.4404808909 1.4487757412997742 1.2958788721935723 0.934963563782636 0.8718175418976271 1.0042053611786166 1.0081415440613712 1.158039913129399 0.9240104213777913 0.9026733584759 1.0 17.638106657537428 -5.121306335124829 3.4860983528671525 0.9778420406551692 1.4245513667940621 0.8159651391919098 0.07671970756230856 0.10267659714021021 2.222383099466884 0.021822344688265615 0.07389989775342011 7.562992415645756e-06 5.121306335124829 0.4467093261388929 AFLAELEQNS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 AFLAELEQNSPK 12 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 AFLAELEQNS(1)PK;AFLAELEQNS(1)PK;AFLAELEQNS(1)PK;AFLAELEQNS(1)PK;AFLAELEQNS(1)PK;AFLAELEQNS(1)PK 160.84 5.6645e-12 13073100.0 288411.7 274749.0 228138.30000000002 300711.2 294760.7 245606.7 316480.8 287333.2 243131.1 241784.0 True False 337234.10441927 302024.2649671165 233577.98229132104 283863.326382865 237004.45679238977 232726.65228611502 286501.4475014296 279791.0079546899 246686.43237864895 285617.5252389088 1.1807192298063145 1.0574430428051782 0.8177998954929023 0.9938582240197744 0.8297966190770123 0.8148192310378977 1.0030947760008122 0.9796002809024228 0.8636950137156485 1.0 18.123724979012366 -5.016452503429782 4.076868214511708 0.9119816723611366 1.164841645999166 0.5739173199739028 0.07453239291355683 0.13815438071445885 5.294179857247548 0.019163174730413974 0.07246899799008294 9.628253065036242e-06 5.016452503429782 0.25285997363802937 AFLAELEQNS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 AFLAELEQNSPK 12 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 AFLAELEQNS(1)PK;AFLAELEQNS(1)PK;AFLAELEQNS(1)PK 152.16 0.00017181 15160600.0 245412.0 208333.0 162692.0 209146.0 204099.0 187932.0 180427.0 175231.0 178686.0 165283.0 True False 241912.37987695145 207850.6177384411 149316.09176928102 224527.29453060383 192094.29809407302 179894.58645088895 189768.62722390884 183372.87197221647 158560.5010330028 193851.94632424612 1.2479233996047536 1.072213210543577 0.7702584090619741 1.1582411153873515 0.9909330380039972 0.9279998981799676 0.9789358880436139 0.9459428984298056 0.8179463969259656 1.0 17.564595694634193 -4.917543178450625 4.035354381176092 0.9541188827427666 1.2401203072838252 0.45985440285769397 0.10009168217168105 0.1981639771954803 5.822834922970314 0.02476249141764446 0.12582466198302922 1.2090849672530344e-05 4.917543178450625 0.2860014245410586 AFLAS(ph)LSPAMVVPEDQLTR ddPTM_PC-9_AZD4547_30min_R2 1 AFLASLSPAMVVPEDQLTR 19 0 Q9H211;H3BSY1 Q9H211 CDT1 DNA replication factor Cdt1 1 AFLAS(0.881)LS(0.119)PAMVVPEDQLTR 171.52 3.3138999999999997e-08 10338000.0 37216.0 34875.0 43788.0 60516.0 56778.0 42762.0 42494.0 55917.0 37582.0 48130.0 True False 49049.91385911148 46147.66173220431 43207.34250942909 46564.971162879796 48895.35475961983 40088.085380055716 46275.883678214086 47276.31249483105 39568.50779482638 46444.983349631846 1.0560863697564504 0.9935984126597842 0.9302908386072568 1.00258343968701 1.0527585808685065 0.86313057921192 0.9963591402295313 1.0178992236673026 0.851943631822618 1.0 15.503235155114 -6.731456103217663 24.999996896824623 0.9501408016610666 1.0018013831201367 0.19731871131242962 0.060952382372387995 416.69818292397133 347441.05024184485 0.020065170792981455 0.020062843571749846 1.8558543824336332e-07 6.731456103217663 0.05166058145907004 AFLASLS(ph)PAMVVPEDQLTR ddPTM_PC-9_AZD4547_30min_R2 2 AFLASLSPAMVVPEDQLTR 19 0 Q9H211;H3BSY1 Q9H211 CDT1 DNA replication factor Cdt1 1 AFLAS(0.299)LS(0.665)PAMVVPEDQLT(0.036)R;AFLAS(0.01)LS(0.815)PAMVVPEDQLT(0.175)R 91.20200000000001 0.00083808 11515600.0 28882.0 25780.0 44452.0 61354.0 48247.0 41923.0 34994.2 48761.0 37483.5 43697.2 True False 38065.87521708022 34112.88084462301 43862.537435579194 47209.78320985074 41548.73685384087 39301.548182687315 38108.616007251854 41226.10786631002 39464.80128591809 42167.37432839255 0.9027328787566773 0.8089875499232541 1.0402008219431684 1.1195808124591478 0.9853290017601325 0.9320368841705282 0.9037464773231608 0.9776778498288249 0.9359084342926531 1.0 15.363839570449368 -5.259418093196374 24.99786769776149 0.9857789958503074 0.855860211062077 0.4215841374033912 0.061344479680712376 183.39009099618866 2268005.563289733 0.017683539783622523 0.0422003648524211 5.502776916586183e-06 5.259418093196374 -0.12991878478823038 AFLASLS(ph)PAMVVPEDQLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AFLASLSPAMVVPEDQLTR 19 0 Q9H211;H3BSY1 Q9H211 CDT1 DNA replication factor Cdt1 1 AFLAS(0.102)LS(0.863)PAMVVPEDQLT(0.035)R;AFLAS(0.017)LS(0.981)PAMVVPEDQLT(0.002)R 89.87700000000001 0.0053289999999999995 5218200.0 18577.7 21753.2 29819.9 25581.6 28800.3 28474.2 29022.7 29253.9 29671.8 25326.4 True False 21722.5376836996 23912.713934109568 30530.919508600517 24148.345888666227 23157.08795968344 26980.96282603571 26273.459749848065 28486.016122069148 30105.69394146942 29917.875836327912 0.7260721918406692 0.7992784669917458 1.020490882294799 0.8071544256943534 0.7740217950755997 0.9018341734433551 0.8781860013586058 0.9521403283410875 1.0062777887764829 1.0 14.86872012732903 -7.750662657944378 1.2546961521709683 1.0091406010188482 0.83693677768944 0.454761326224118 0.07460688178983871 0.4772018078593299 1.3715018672455088 0.06563774724950167 0.02571885648755388 1.7755681335328976e-08 7.750662657944378 -0.1722038233294082 AFLASLS(ph)PAMVVPEDQLTR ddPTM_PC-9_Lapatinib_30min_R1 2 AFLASLSPAMVVPEDQLTR 19 0 Q9H211;H3BSY1 Q9H211 CDT1 DNA replication factor Cdt1 1 AFLAS(0.084)LS(0.916)PAMVVPEDQLTR;AFLAS(0.058)LS(0.692)PAMVVPEDQLT(0.25)R 112.91 8.709399999999999e-05 5050100.0 34939.0 27634.1 28421.5 29973.6 27223.6 28633.9 29139.2 29163.0 27604.5 23189.0 True False 34440.76345297211 27570.114939284027 26084.793980162674 32177.958532998444 25622.361371656905 27409.294845881024 30647.885196799394 30518.019444765738 24495.390521728208 27197.18775259976 1.2663354669704754 1.013711976035045 0.9590989413112849 1.1831355074541696 0.9420959845088278 1.0077988612356066 1.1268769946212467 1.1221020247524873 0.9006589484380315 1.0 14.731169860983401 -4.758293875426437 24.972721865229428 1.034610803942647 1.2663357893006182 0.4101414886426299 0.08531415003588483 89.70328924800961 712048.676214651 0.02075645687818893 0.14418573464840492 1.744641201503496e-05 4.758293875426437 0.23172498535797126 AFLASPEYVNLPINGNGKQ ddPTM_PC-9_Lapatinib_30min_R1 1 AFLASPEYVNLPINGNGKQ 19 1 P09211;A8MX94 P09211 GSTP1 Glutathione S-transferase P 0 94.68799999999999 0.0016940000000000002 3777600.0 25491.0 17090.0 19610.0 17746.0 23491.0 22586.0 15144.0 11344.0 23148.0 12877.0 False True 25127.493665523107 17050.429155006474 17997.74149678906 19051.10003892061 22109.30556508296 21620.049430537554 15928.082219838912 11871.08365330804 20540.828480753666 15102.772292476047 1.6637669680050204 1.1289602216608083 1.1916846224156634 1.2614306612046025 1.4639236516925738 1.4315285307789687 1.0546462537724959 0.7860201705631236 1.3600700641554908 1.0 13.882525777146174 -7.299062096316021 9.31028099297883 1.0318542139475049 1.3394951132260071 0.3749790266062163 0.19262679336207378 0.5316556644163186 127.28444360330694 0.07968772670411968 0.05395452177768176 5.0227076868299895e-08 7.299062096316021 0.30764089927850224 AFLIEEQK ddPTM_PC-9_Lapatinib_30min_R1 2 AFLIEEQK 8 0 P49207 P49207 RPL34 60S ribosomal protein L34 0 ; 122.18 0.015388999999999998 16299300.0 124910.0 104984.0 125103.0 106871.0 136492.0 103070.0 105616.0 99982.0 111222.0 102447.0 False True 123128.76049431135 104740.91599819764 114817.51425154525 114730.64985120499 128463.80891359667 98661.93636790512 111084.279696943 104627.52872223612 98695.00714041757 120154.82744795288 1.0247508411399175 0.8717162532946748 0.9555797023742589 0.9548567651258335 1.069152289942266 0.8211233661056375 0.9245095020843924 0.8707725768867449 0.8213986007609141 1.0 16.874535087076985 -6.77972944735794 24.9999722304477 0.8817934092891615 0.9672400584162437 0.28769433197441063 0.0680845412723194 327.68644306004865 447898.7495406134 0.023308573790813702 0.020595267172786695 1.660621103193949e-07 6.77972944735794 0.08544664912708222 AFLS(ph)PPTLLEGPLR ddPTM_PC-9_Lapatinib_30min_R1 1 AFLSPPTLLEGPLR 14 0 Q96PC5;Q96PC5-11;Q96PC5-13;G3V599;Q96PC5-10;Q96PC5-9;Q96PC5-6;Q96PC5-12;Q96PC5-7;Q96PC5-14 Q96PC5 MIA2 Melanoma inhibitory activity protein 2 1 AFLS(0.9)PPT(0.1)LLEGPLR 149.32 3.7613e-08 0.0 8286.4 8186.7 3204.1 1892.6 2995.3 3639.4 4137.6 3911.6 5644.0 700.61 True False 8168.234416460345 8167.7441991393525 2940.6712661836737 2031.7881175285193 2819.122342986377 3483.7513458557673 4351.824682567713 4093.3472159978623 5008.313286045176 821.7095049958565 9.940537826079465 9.939941243810413 3.578723683132401 2.472635530166789 3.430801671206898 4.239638612764172 5.296062241107528 4.98150160258704 6.094992519370249 1.0 9.682484644784365 -5.25879533342084 24.853870714919303 4.025132319086181 9.940240295619452 0.7550171307207405 1.3774767623536697 100.06959370986998 940632.9589022342 0.36478511572428274 0.8785127017752632 5.5106733243353325e-06 5.25879533342084 5.915107976533271 AFMGT(ph)PVQK ddPTM_PC-9_AZD4547_30min_R2 2 AFMGTPVQK 9 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 AFMGT(1)PVQK;AFMGT(1)PVQK 126.71 0.0033883000000000003 45442000.0 125303.0 131034.0 150286.0 193869.0 179604.0 151861.0 123337.0 156357.0 128395.0 144190.0 True False 165146.74753568997 173388.1779904707 148293.10944487204 149175.49729619184 154669.08479070707 142365.10766336106 134313.7540645711 132195.6183764203 135181.69757641255 139141.95198802027 1.1868939969299024 1.2461243752380227 1.0657684999103625 1.072110137631499 1.1115920294407229 1.0231645138600491 0.965300199871676 0.9500773597584857 0.9715380274962027 1.0 17.08619793960829 -5.635255463720319 0.5018410752083666 0.9596400975141177 1.2856009164352216 0.7983753024539932 0.04198190906881979 0.9078359851528777 0.32033674259013345 0.032110720415163524 0.1598496065276266 2.316031896815194e-06 5.635255463720319 0.32596081892110385 AFMGT(ph)PVQK ddPTM_PC-9_Lapatinib_30min_R1 2 AFMGTPVQK 9 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 AFMGT(1)PVQK;AFMGT(1)PVQK 134.75 0.0026835 36860000.0 431080.0 456210.0 522420.0 361490.0 365130.0 401420.0 320170.0 258320.0 357730.0 250370.0 True False 424932.7201496093 455153.6737744586 479468.64419951686 388075.18049528945 343653.7712731999 384252.2023557239 336746.83599615854 270322.4902435241 317438.6803360984 293646.1209029452 1.4470912091158068 1.55000744561136 1.632811094950541 1.3215743470473245 1.1702990327830112 1.30855534945999 1.1467777437709072 0.9205723181777363 1.0810245998141998 1.0 18.163719054240318 -6.551948431247358 0.6823670619443786 0.9944753856185963 1.5716172317401766 0.8124507216043787 0.0968284113516049 0.3261620751095884 0.337789340865808 0.0720211489127968 0.09371696358629997 2.8057667789632175e-07 6.551948431247358 0.5771418461215804 AFQLEEGEET(ph)EPDCK ddPTM_PC-9_AZD4547_30min_R2 5 AFQLEEGEETEPDCK 15 0 P38432 P38432 COIL Coilin 1 AFQLEEGEET(1)EPDCK;AFQLEEGEET(1)EPDCK;AFQLEEGEET(1)EPDCK;AFQLEEGEET(1)EPDCK;AFQLEEGEET(1)EPDCK 208.38 1.4362e-28 34273800.0 96543.8 97949.5 119825.1 112551.8 102941.8 126196.0 132936.8 124055.2 108892.5 111580.1 True False 127242.72016421107 129609.76036813032 118236.14088167064 86604.7214179756 88650.10797481138 118304.94417056076 144767.91766729474 104885.31934489962 114648.33524155524 107673.71466133895 1.1817435719053773 1.2037270263758038 1.0980966083835149 0.8043255653468383 0.8233217201954849 1.098735606388799 1.3445056495229726 0.9741032867194233 1.0647755174245936 1.0 16.716306576165827 -5.521977548439462 24.999523288833515 1.018168868756502 1.1822794653137563 0.1992853014747713 0.14198077738867165 57.7639119674177 1602393.5684479761 0.04306472463692342 0.07581221475404433 3.006231710655417e-06 5.521977548439462 0.16411059655725424 AFQLEEGEET(ph)EPDCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AFQLEEGEETEPDCK 15 0 P38432 P38432 COIL Coilin 1 AFQLEEGEET(1)EPDCK;AFQLEEGEET(1)EPDCK;AFQLEEGEET(1)EPDCK;AFQLEEGEET(1)EPDCK 151.11 0.00025860000000000005 34627900.0 248128.0 232274.0 203754.0 240804.0 250164.0 191605.0 228408.0 224191.0 200545.0 187535.2 True False 290131.16964861215 255332.6276746121 208612.26810134773 227312.53257710105 201146.16001730037 181556.89649867476 206771.54070928282 218306.22379999977 203477.59123113507 221533.8472321735 1.3096471409380022 1.152567117236115 0.9416722126561383 1.02608488687903 0.9079703283737665 0.8195447276659182 0.9333632006696504 0.985430562992972 0.9184943690247253 1.0 17.757167613413287 -4.871783414623346 1.3046190179727253 0.929460111003505 1.4467237532879467 0.826929492665398 0.055123073804938826 0.45846504282986755 0.7741485762122404 0.017148329550470732 0.3047613467728601 1.3434347734351241e-05 4.871783414623346 0.5172636422844417 AFQLEEGEET(ph)EPDCK ddPTM_PC-9_Lapatinib_30min_R1 6 AFQLEEGEETEPDCK 15 0 P38432 P38432 COIL Coilin 1 AFQLEEGEET(1)EPDCK;AFQLEEGEET(1)EPDCK;AFQLEEGEET(1)EPDCK;AFQLEEGEET(1)EPDCK;AFQLEEGEET(1)EPDCK;AFQLEEGEET(1)EPDCK 199.61 5.8301e-10 43076500.0 124617.6 195411.4 180000.1 179754.2 183622.4 183551.2 177726.8 167416.0 167786.8 135021.0 True False 122840.53017193105 194958.93690934082 165201.18659847896 192973.92351043285 172822.09144752845 175701.14305474577 186928.624080089 175194.7585421565 148888.88371066688 158359.1999458267 0.7757082014430089 1.231118476072338 1.0432054888821922 1.2185835971414831 1.091329657554783 1.10951017127424 1.1804089951454393 1.1063124757013745 0.940197246270507 1.0 17.272841158226477 -10.532284815453718 10.309237579231906 0.9999990257293679 1.0902821114772923 0.022526444602337548 0.1299019692781915 0.0 0.0 0.11793572050439946 0.028603613686644803 2.935723738190208e-11 10.532284815453718 0.09028308574792432 AFQLEEGEET(ph)EPDCKYSK ddPTM_PC-9_AZD4547_30min_R2 2 AFQLEEGEETEPDCKYSK 18 1 P38432 P38432 COIL Coilin 1 AFQLEEGEET(0.999)EPDCKYS(0.001)K;AFQLEEGEET(0.995)EPDCKY(0.003)S(0.002)K 73.672 0.030206999999999998 8055900.0 17366.9 10147.6 20928.5 44818.0 32430.0 19365.8 14194.2 17452.0 14737.8 24555.1 True False 22889.212946039435 13427.613252866422 20650.974415561017 34485.90253119749 27927.654282547315 18154.853464596683 15457.456302191056 14755.19440706388 15516.81002018497 23695.433422990754 0.9659757024672495 0.5666751484629158 0.8715170576084159 1.45538179933595 1.1786091346803642 0.7661752009558828 0.6523390404495952 0.6227020263215566 0.6548438993789248 1.0 14.532321429694074 -6.920775662041957 7.236551461408601 0.7021629426556951 0.9996915486154214 0.24517535385939304 0.2333709014913765 0.347582252158295 26.67820768757255 0.0915906802733612 0.08071124629219677 1.2001190732559614e-07 6.920775662041957 0.2975286059597263 AFRLHS(ph)S(ph)LIQHQR ddPTM_PC-9_AZD4547_30min_R2 1 AFRLHSSLIQHQR 13 1 Q9Y2G7 Q9Y2G7 ZFP30 Zinc finger protein 30 homolog 2 AFRLHS(1)S(1)LIQHQR 93.10600000000001 0.013797 173430000.0 1927.1 3691.0 25173.0 38978.0 22288.0 13978.0 3891.8 26569.0 11331.0 10991.0 True False 2539.877713829904 4884.043568561039 24839.189572253992 29992.224304096893 19193.695918884197 13103.953450316141 4238.162660584407 22463.37154488198 11929.933527305024 10606.208435400029 0.2394708466554956 0.46048911807726794 2.3419480885694233 2.827798877117362 1.8096661060159789 1.235498390412493 0.3995926241123846 2.1179455110373513 1.124806626229109 1.0 13.372621385560429 -6.856022926258334 7.990669373226929 1.1933979304320212 1.5918919939823182 0.043544990174904874 0.823057932110346 0.9923174285223946 73.77543860669991 0.3233874667060193 0.2854239931409592 1.393083260611558e-07 6.856022926258334 0.39849406355029693 AFRLHS(ph)S(ph)LIQHQR ddPTM_PC-9_Lapatinib_30min_R1 3 AFRLHSSLIQHQR 13 1 Q9Y2G7 Q9Y2G7 ZFP30 Zinc finger protein 30 homolog 2 AFRLHS(1)S(1)LIQHQR;AFRLHS(1)S(1)LIQHQR;AFRLHS(1)S(1)LIQHQR 100.11 0.007521600000000001 182924000.0 43429.0 30979.2 260385.0 44596.0 102245.0 169254.0 55410.0 62591.0 227655.0 54297.0 True False 42809.694496096825 30907.46956575639 238977.15041516675 47875.73860789488 96231.15012140413 162015.40097034446 58278.858676787764 65499.206359679454 202014.09658657238 63682.16410379525 0.6722399450232488 0.48533949812667254 3.752654354297053 0.7517919543353213 1.5111162046025548 2.5441252389959037 0.9151519816725973 1.028532985357134 3.1722241137614384 1.0 15.958601743206813 AFS(ph)DPFVEAEK ddPTM_PC-9_AZD4547_30min_R2 3 AFSDPFVEAEK 11 0 A0A087WYC1;P34932;A0A087WTS8;P34932-2 A0A087WYC1 HSPA4 Heat shock 70 kDa protein 4 1 AFS(1)DPFVEAEK;AFS(1)DPFVEAEK;AFS(1)DPFVEAEK 164.48 7.7503e-05 14691800.0 56281.0 50897.0 58784.0 76117.0 78754.0 71157.0 60887.0 77462.0 71841.0 71097.0 True False 74177.18728247673 67348.45990491773 58004.48575121675 58569.40164592705 67820.36649299209 66707.54154128958 66305.82504625175 65492.027799678144 75638.36859369173 68607.9156702425 1.0811753506549073 0.9816427047371878 0.8454488842076163 0.8536828596781074 0.9885210158396929 0.9723009493818923 0.9664456994283935 0.9545841344963667 1.1024729122691972 1.0 16.066087417163146 -8.23653274019297 21.336737565634486 1.0512363063209784 0.9513148319382015 0.24073986190780683 0.06770364450013096 153.57189472895817 131561.7048526406 0.04872121421010358 0.018376026022981867 5.800524424143418e-09 8.23653274019297 -0.09992147438277688 AFS(ph)DPFVEAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AFSDPFVEAEK 11 0 A0A087WYC1;P34932;A0A087WTS8;P34932-2 A0A087WYC1 HSPA4 Heat shock 70 kDa protein 4 1 AFS(1)DPFVEAEK;AFS(1)DPFVEAEK;AFS(1)DPFVEAEK;AFS(1)DPFVEAEK 172.76 0.00015079 17269400.0 76039.0 85338.0 79116.0 103351.0 102827.0 90044.0 94998.0 92689.0 82779.0 67145.0 True False 88910.90086129257 93809.79266080594 81002.4254891007 97560.57853846283 82678.7874997956 85321.93412659748 85999.10171403982 90256.01196211319 83989.48627251804 79317.85698047237 1.1209443150132252 1.1827071006709298 1.0212381999811602 1.2299951392090904 1.0423729365274035 1.0756964115609338 1.0842338029280385 1.137902805219936 1.0588975732563704 1.0 16.27535807873231 -14.522878717131446 0.09905676472522877 0.6554910183950349 1.1812756696764104 0.2720771044541861 0.05877423730412894 257.00433903005535 1.7292339603625027 18.271515935823242 0.9840153089964764 3.0000001944456594e-15 14.522878717131446 0.5257846512813755 AFS(ph)DPFVEAEK ddPTM_PC-9_Lapatinib_30min_R1 5 AFSDPFVEAEK 11 0 A0A087WYC1;P34932;A0A087WTS8;P34932-2 A0A087WYC1 HSPA4 Heat shock 70 kDa protein 4 1 AFS(1)DPFVEAEK;AFS(1)DPFVEAEK;AFS(1)DPFVEAEK;AFS(1)DPFVEAEK;AFS(1)DPFVEAEK 128.54 0.00030471 16035000.0 84111.2 89346.2 103866.4 94528.9 102319.9 86166.0 90378.0 81070.9 91956.1 87014.3 True False 82911.75886389482 89139.32436331436 95326.90552789862 101480.87064516653 96301.64465066332 82480.8810427565 95057.33061704983 84837.74997787108 81599.0356773385 102054.60581573345 0.8124254481331069 0.8734473437118702 0.9340774457550485 0.9943781550476729 0.9436285984440772 0.808203416038678 0.9314359685900147 0.831297610722748 0.7995624991651148 1.0 16.638981768395617 -6.735351973684058 24.999525219004795 0.8671394358750896 0.9153207652231251 0.059238123668549525 0.07131252948842003 580.4320886760373 556225.9320392528 0.023980577238724834 0.023973108844573276 1.8392807533542323e-07 6.735351973684058 0.04818132934803554 AFS(ph)EDEALAQQENR ddPTM_PC-9_AZD4547_30min_R2 1 AFSEDEALAQQENR 14 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 AFS(1)EDEALAQQENR 92.26899999999999 0.018746000000000002 0.0 1836.7 6144.8 5828.1 6657.1 6513.4 5100.2 7913.4 7311.3 5555.0 4915.5 True False 2420.7323942667153 8130.986431886718 5750.8155859871085 5122.408446169726 5609.126839467886 4781.283687745199 8617.677269712885 6181.506581960016 5848.625959242731 4743.409841161759 0.5103359134731289 1.7141648527455244 1.212380076476507 1.0799000334567637 1.1825094240842777 1.0079845191226748 1.8167684341613286 1.3031778380857846 1.2330003425995935 1.0 12.211708810525682 AFS(ph)EDEALAQQENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AFSEDEALAQQENR 14 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 AFS(1)EDEALAQQENR;AFS(1)EDEALAQQENR 170.42 3.5338e-05 5885100.0 10557.8 11180.400000000001 17678.7 17665.8 20441.8 18858.6 19459.8 19395.8 18116.9 14820.2 True False 12345.027013944866 12290.316223310521 18100.227254843106 16676.042499296353 16436.376032689124 17869.621817332078 17616.42686724852 18886.68080154882 18381.825388692538 17506.984943361356 0.705148662312987 0.702023578764258 1.0338860353967865 0.9525365191805859 0.9388467566439413 1.0207138393700528 1.0062513290690105 1.078808307806916 1.049970937209432 1.0 14.095643023469325 -5.258721784743339 24.933986802575415 1.0085785015225386 0.7035860831550145 0.9064182244049187 0.039395952810129406 65.47917452994483 600764.0512364187 0.011437558543583658 0.027601093556045436 5.511606647399304e-06 5.258721784743339 -0.3049924183675241 AFS(ph)EGQITR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AFSEGQITR 9 0 Q96GN5-5;Q96GN5-4;Q96GN5-2;Q96GN5 Q96GN5-5 CDCA7L Cell division cycle-associated 7-like protein 1 AFS(0.995)EGQIT(0.005)R 74.69800000000001 0.02705 4709100.0 12362.0 14181.0 18553.0 15611.0 23140.0 17199.0 15236.0 17176.0 12552.0 11562.0 True False 14454.64243937055 15588.795961035972 18995.373882644315 14736.36628154486 18605.883111879903 16297.054162890892 13792.735780912359 16725.148199476305 12735.549253949004 13658.099075258362 1.0583202215566825 1.1413591214369696 1.3907772800575464 1.0789470921498716 1.3622600780209926 1.1932154008468863 1.0098576459954 1.2245590039520142 0.9324540101645217 1.0 13.737469083855675 -7.936793634174567 1.0501414187216036 0.9816709402904203 1.2055978026579042 0.2956408669308377 0.1222781610936685 0.6596621216582473 1.3290100725379084 0.10926763841883717 0.040556455784425675 1.156661728220994e-08 7.936793634174567 0.22392686236748383 AFS(ph)LASADLLR ddPTM_PC-9_AZD4547_30min_R2 1 AFSLASADLLR 11 0 Q9P219-3;Q9P219-2;Q9P219 Q9P219-3 CCDC88C Protein Daple 1 AFS(0.992)LAS(0.008)ADLLR 126.34 0.00041543 1150900.0 3031.2 3392.5 4783.8 6463.6 5510.4 3497.0 3536.6 4175.0 3173.7 4584.2 True False 3995.0585471232453 4489.059281046685 4720.363686320606 4973.516881624528 4745.376076427649 3278.3320371838267 3851.350548697979 3529.84968195575 3341.4553027630363 4423.708553321886 0.90310166209373 1.0147728375269491 1.0670602797229833 1.1242867430517716 1.0727144474434724 0.7410822837146529 0.8706157971925823 0.7979390231992312 0.7553515930098614 1.0 12.11104062445538 -6.753249836618426 24.99928774002292 0.8227200526980865 1.0417737953665653 0.5816343992089483 0.08596725718420635 123.7226933018626 377673.74187723256 0.028520423181974106 0.028051325171062964 1.7650221641460719e-07 6.753249836618426 0.21905374266847888 AFS(ph)LASADLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AFSLASADLLR 11 0 Q9P219-3;Q9P219-2;Q9P219 Q9P219-3 CCDC88C Protein Daple 1 AFS(1)LASADLLR;AFS(0.998)LAS(0.002)ADLLR 115.92 0.0013119000000000002 2143830.0 9617.8 8160.9 10326.3 9762.0 11824.599999999999 11876.900000000001 12330.5 9895.8 10820.1 9872.4 True False 11245.903579791153 8971.060218490824 10572.51815471083 9215.066788831014 9507.654513601341 11254.05445591249 11162.465774910728 9636.045735466796 10978.323492881897 11662.187970124598 0.9643047778513042 0.7692433222198336 0.9065638610691913 0.7901662031548066 0.8152547822035973 0.9650036926811987 0.9571502194533287 0.8262639703760362 0.9413605338042416 1.0 13.509550860842902 -6.758370749682159 24.999962546593007 0.9282968415847012 0.8445873429787712 0.2960510003020729 0.06750908541372196 109.73021097967734 893967.7073275335 0.022102292575031737 0.021207524578792436 1.7443324107403723e-07 6.758370749682159 -0.08370949860592991 AFS(ph)LASADLLR ddPTM_PC-9_Lapatinib_30min_R1 2 AFSLASADLLR 11 0 Q9P219-3;Q9P219-2;Q9P219 Q9P219-3 CCDC88C Protein Daple 1 AFS(1)LASADLLR;AFS(1)LASADLLR 138.42 0.00010116 2225430.0 13189.5 9037.2 13090.3 9085.5 9847.900000000001 10853.7 9815.6 9487.900000000001 9834.3 7044.299999999999 True False 13001.415311341938 9016.274918643912 12014.066064019265 9753.677978339512 9268.665883716334 10389.512552210459 10323.803739900339 9928.742471281857 8726.657574229988 8261.89786906026 1.573659650288169 1.0913079611415553 1.4541533016294466 1.1805614318794446 1.121856748971237 1.2575213004166805 1.249568065778403 1.201750811815735 1.0562533830041876 1.0 13.012257510831551 -1.522878745280971 0.11059278481708501 0.9188960470422454 2.3422675112896387 0.4372999658681266 0.12673974998167448 113.04383727427651 0.8753421524446602 1.1151918227304145 24.55953981856299 0.029999999999956253 1.522878745280971 1.4233714642473934 AFS(ph)SPQEEEEAGFTGR ddPTM_PC-9_Lapatinib_30min_R1 1 AFSSPQEEEEAGFTGR 16 0 A0A024RAC6;Q14241 A0A024RAC6 TCEB3 Transcription elongation factor B polypeptide 3 1 AFS(0.909)S(0.091)PQEEEEAGFTGR 234.36 6.3120000000000005e-37 4887400.0 11076.0 11355.0 12428.0 11899.0 12313.0 14429.0 16249.0 15134.0 14567.0 10869.0 True False 10918.05420891036 11328.708195149122 11406.217813467332 12774.092153900381 11588.7735482894 13811.90530564182 17090.293713032388 15837.180889383264 12926.311062689592 12747.69216796786 0.8564730042936731 0.8886869910159635 0.8947672773373555 1.0020709619894068 0.9090879663229893 1.0834828079978345 1.3406578608774793 1.2423567090189556 1.014011861313263 1.0 13.637948465912437 -6.879661378717105 3.9226573216344987 1.1744218032333054 0.9129464515917295 0.5565350044483793 0.10075623623014339 0.15991278983507543 4.5704128241636885 0.03723952734342762 0.032722161349471535 1.319284989841799e-07 6.879661378717105 -0.26147535164157587 AFS(ph)T(ph)CSSHLIVVSLFY(ph)GTASLTYLRPK ddPTM_PC-9_Lapatinib_30min_R1 1 AFSTCSSHLIVVSLFYGTASLTYLRPK 27 1 Q8NGE5 Q8NGE5 OR10A7 Olfactory receptor 10A7 3 AFS(0.477)T(0.5)CS(0.513)S(0.501)HLIVVS(0.013)LFY(0.48)GT(0.217)AS(0.215)LT(0.053)Y(0.03)LRPK 52.577 0.023309 0.0 2807.6 2510.0 2646.5 2687.3 1901.1 2831.5 2054.0 3501.1 3112.6 2705.2 True False 2767.563109149218 2504.1882492139393 2428.914985785429 2884.933006570006 1789.2810357064072 2710.4033455488816 2160.346069700813 3663.773887393932 2762.0262108689235 3172.790215547578 0.8722805231771606 0.7892700364942825 0.7655454098046105 0.9092731667013503 0.563945585478176 0.8542649092483743 0.6808978605375484 1.1547482305764794 0.8705354036123177 1.0 11.631536418273548 -7.753916536528645 24.999998460509218 1.0094813748250437 0.776489673693334 0.46888704640424317 0.11311529072798218 136.9591922416001 455148.46596933657 0.05118619888391549 0.028812883002182002 1.762314698583132e-08 7.753916536528645 -0.23299170113170975 AFS(ph)TEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AFSTEK 6 0 H0YJD9;Q9NZ32 H0YJD9 ACTR10 Actin-related protein 10 1 AFS(0.958)T(0.042)EK;AFS(0.974)T(0.026)EK 84.916 0.041893 50790000.0 218997.0 185383.0 174861.0 249028.0 248139.0 214887.0 210469.0 247366.0 183421.0 178996.0 True False 256068.8667120886 203786.59908643432 179030.3494040351 235075.7685196697 199517.94423071583 203617.94743305628 190531.85265639544 240872.90460594228 186103.18512656022 211446.55786844343 1.2110335079155463 0.963773547040785 0.8466931370688151 1.1117502733997107 0.9435856806657063 0.9629759381552198 0.901087511554288 1.1391668279405482 0.8801428928549823 1.0 17.689933549409595 -4.760011300324909 24.985463635344782 0.9735245743980896 1.2110337993666405 0.3957568250381781 0.08854424119702535 36.30041803582006 634881.6018617979 0.02088940835959023 0.12758862949604216 1.737755611830149e-05 4.760011300324909 0.23750922496855087 AFS(ph)VEALVGR ddPTM_PC-9_Lapatinib_30min_R1 1 AFSVEALVGR 10 0 A0A0D9SGI2;Q9Y458 A0A0D9SGI2 TBX22 T-box transcription factor TBX22 1 AFS(1)VEALVGR 60.49 0.038528 430960.0 4193.7 5544.9 3417.6 3642.7 5587.0 4506.5 3623.6 4372.7 5774.0 4196.5 True False 4133.897068969607 5532.06112472764 3136.6181203175047 3910.5963096909777 5258.383644464627 4313.767500164592 3811.2122775890307 4575.871605326166 5123.671317084488 4921.859433515235 0.8399055529339126 1.1239778785751697 0.6372831574503753 0.7945363662891112 1.0683733892637897 0.8764507719968877 0.7743439911421911 0.9297038379777618 1.0410031790414456 1.0 12.26498774020982 -8.073405805207482 4.909073144568872 1.0152112102238662 0.87696276549901 0.1616773287776614 0.132254427768658 0.43963862066244025 19.312909632298688 0.09460795913124914 0.03468744879538412 8.444893846377972e-09 8.073405805207482 -0.1382484447248562 AFSNSS(ph)HLIGHGR ddPTM_PC-9_AZD4547_30min_R2 1 AFSNSSHLIGHGR 13 0 Q147U1-3;Q147U1 Q147U1-3 ZNF846 Zinc finger protein 846 1 AFS(0.006)NS(0.006)S(0.988)HLIGHGR 72.243 0.024038999999999998 5697700.0 898.61 687.41 1417.4 3165.9 1125.6 0.0 977.06 1330.6 1495.6 985.91 True False 1184.349287750865 909.60183946479 1398.6043498872918 2436.0506676674127 969.3298692702818 0.0 1064.0164471839762 1124.9863441461844 1574.654362672085 951.3935909876483 1.2448573324121133 0.9560731206109199 1.4700586204657853 2.560507754880429 1.0188526372812894 0.0 1.1183767236432751 1.1824615540854424 1.6551029748239374 1.0 9.893898496469374 -6.48632011351784 24.99851740365737 0.9548614475095131 1.5437489340320818 0.20265783255639025 0.5437465344069462 1004.2609670213238 686706.6268015769 0.18159499327950746 0.20584239647877953 3.26347196695421e-07 6.48632011351784 0.5888874865225687 AFSS(ph)PQEEEEAGFTGR ddPTM_PC-9_AZD4547_30min_R2 1 AFSSPQEEEEAGFTGR 16 0 A0A024RAC6;Q14241 A0A024RAC6 TCEB3 Transcription elongation factor B polypeptide 3 1 AFS(0.157)S(0.843)PQEEEEAGFTGR 112.64 0.00032365 7827200.0 8722.0 11578.0 14377.0 16523.0 15236.0 13573.0 9952.2 14038.0 10409.0 11397.0 True False 11495.4145711299 15320.362079869874 14186.351586235083 12713.877627805257 13120.74439250356 12724.278164339745 10837.926520033952 11868.749661148453 10959.198489605333 10997.99449897682 1.0452282524963399 1.3930141610177365 1.2899034990020124 1.1560178202478708 1.1930124527452917 1.1569634959831565 0.9854457120379758 1.079173995063613 0.9964724469197456 1.0 13.424952849647944 -6.945407606435044 1.1694081437545247 1.0114982869906837 1.242622944966128 0.5238264448435046 0.08877661390763036 0.37098046074493635 1.050825988094422 0.04974314354739269 0.037656574323329355 1.1339460527164859e-07 6.945407606435044 0.23112465797544424 AFSS(ph)PQEEEEAGFTGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AFSSPQEEEEAGFTGR 16 0 A0A024RAC6;Q14241 A0A024RAC6 TCEB3 Transcription elongation factor B polypeptide 3 1 AFS(0.009)S(0.991)PQEEEEAGFTGR;AFS(0.151)S(0.849)PQEEEEAGFTGR 143.64 3.9192000000000005e-06 7779200.0 23468.0 25709.0 32667.0 32483.0 33404.0 31850.0 36458.0 32550.0 30112.0 26151.0 True False 27440.66888587188 28261.21961513811 33445.90517028741 30663.082821306896 26858.72599262038 30179.72993127945 33004.434306937736 31695.596989575784 30552.33103369281 30891.9692887979 0.8882783945995462 0.9148403376597375 1.0826731328654928 0.992590745337365 0.8694403953832732 0.9769441905480359 1.0683823358229823 1.0260141298622 0.9890056133382131 1.0 14.914944221788058 -7.012290271874377 24.59385159758718 1.0229676442022124 0.9539978951897661 0.24335527171479787 0.058993025203830936 791.4762146985851 1583809.0779438936 0.02337182159949456 0.019116528541442336 9.720972804066143e-08 7.012290271874377 -0.06896974901244635 AFSS(ph)PQEEEEAGFTGR ddPTM_PC-9_Lapatinib_30min_R1 1 AFSSPQEEEEAGFTGR 16 0 A0A024RAC6;Q14241 A0A024RAC6 TCEB3 Transcription elongation factor B polypeptide 3 1 AFS(0.059)S(0.941)PQEEEEAGFTGR 149.31 3.0585e-05 5465900.0 8790.4 10609.0 9551.1 7815.4 11434.0 12911.0 11368.0 13167.0 10289.0 11302.0 True False 8665.047284038072 10584.43551231502 8765.845426312186 8390.170587410119 10761.474600108919 12358.826627010994 11956.579415948805 13778.786888496734 9130.144472026715 13255.535641031627 0.6536927302444117 0.7984917244348546 0.6612969602811142 0.6329559826642467 0.8118475851551024 0.9323521102199047 0.9020065080537379 1.039474168501001 0.6887797460077707 1.0 13.69430734858876 -6.517315295589675 3.7829536188420434 0.9131360008861725 0.6936498531559115 0.5503429404230422 0.09597964834761867 0.17270189853797105 5.467873104663662 0.030827588445789485 0.03283120963442849 3.0386781597647795e-07 6.517315295589675 -0.21948614773026098 AFVDRT(ph)PPPAAVAQR ddPTM_PC-9_AZD4547_30min_R2 1 AFVDRTPPPAAVAQR 15 1 Q5JTD0-4;Q5JTD0-2;Q5JTD0 Q5JTD0-4 TJAP1 Tight junction-associated protein 1 1 AFVDRT(1)PPPAAVAQR 74.726 0.011318 43813000.0 68735.0 60116.0 88207.0 122930.0 96334.0 83875.0 74446.0 106370.0 71896.0 86758.0 True False 90591.30022318423 79547.32136754668 87037.31754657003 94590.38774956735 82959.68694588068 78630.28299079034 81071.5497789883 89932.9606394331 75696.27578140698 83720.62882708012 1.0820666482366619 0.9501519814411196 1.0396161467723843 1.1298336989911777 0.9909109392528439 0.9391984280624124 0.9683581085664881 1.0742031193433124 0.9041532157833292 1.0 16.35329552729098 -6.495459371511952 24.517926220007084 0.9794671637214932 1.0447198936195776 0.25979466567868437 0.058670222239554384 902.5564119267556 807050.6598902364 0.018344276476922976 0.02074114845323484 3.195513292854611e-07 6.495459371511952 0.0652527298980844 AFVDRT(ph)PPPAAVAQR ddPTM_PC-9_Lapatinib_30min_R1 1 AFVDRTPPPAAVAQR 15 1 Q5JTD0-4;Q5JTD0-2;Q5JTD0 Q5JTD0-4 TJAP1 Tight junction-associated protein 1 1 AFVDRT(1)PPPAAVAQR 57.93600000000001 0.043731 29387000.0 102520.0 71903.0 106520.0 93173.0 98242.0 106680.0 92266.0 83487.0 108130.0 72793.0 True False 101058.04600013455 71736.51302120723 97762.3367790906 100025.25323601664 92463.5987112035 102117.54508322616 97043.08201899468 87366.1108042778 95951.260740621 85375.17305942455 1.183693600595036 0.8402502794492227 1.145090935406293 1.1715964917153965 1.0830267793055615 1.1961035207758612 1.1366662993637366 1.0233198677496969 1.1238777890831926 1.0 16.381528977364717 -4.462327169775429 24.225608476773672 1.0864571650148642 4.032981230564626 0.08611473305506245 0.09935842456916172 2143.8068877769947 1052903.0983650459 0.02402730446838703 77546.44784797386 3.4488382795894225e-05 4.462327169775429 2.946524065549762 AFVEDS(ph)EDEDGAGEGGSSLLQK ddPTM_PC-9_AZD4547_30min_R2 1 AFVEDSEDEDGAGEGGSSLLQK 22 0 A0A494C108;Q8N9T8;H0YFD2;F8WFC1 A0A494C108 KRI1 Protein KRI1 homolog 1 AFVEDS(1)EDEDGAGEGGSSLLQK 65.387 0.016684 0.0 3126.1 3320.2 3714.2 6368.9 3782.7 3181.0 3905.1 4157.0 4902.9 3023.5 True False 4120.134773080623 4393.389719950247 3664.947281184833 4900.64850352411 3257.537399154846 2982.0915671380494 4252.646334818892 3514.631168356897 5162.057284531271 2917.648185281778 1.4121424213737792 1.5057983145853298 1.2561306396270953 1.679657104734449 1.1164942420363277 1.0220874408989264 1.457559672983048 1.2046110240729604 1.7692528216978067 1.0 11.510590215913318 -6.2766579361800074 24.93361924655521 1.2697137019844817 1.451651053075983 0.15164137594032212 0.2326611590430906 1696.1981522300555 2778992.5654117125 0.07109912308554334 0.08090495234415668 5.288616356220642e-07 6.2766579361800074 0.18193735109150122 AFYPEEISSMVLTK ddPTM_PC-9_Lapatinib_30min_R1 2 AFYPEEISSMVLTK 14 0 A0A0G2JIW1;P0DMV9;P0DMV8 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 ; 135.1 0.00015826 35689500.0 45211.0 44952.0 49772.0 37818.0 50091.0 49179.0 44979.0 41525.0 38117.0 43134.0 False True 44566.282849318 44847.916405842676 45679.938285476026 40599.26187714973 47144.74586269506 47075.72881184832 47307.79253606274 43454.40309446545 33823.8620701956 50589.654427557754 0.8809366925630028 0.886503711347999 0.9029501941130625 0.8025210359024325 0.9319048804771802 0.9305406282080613 0.9351278057019642 0.858958290705273 0.6685924711865732 1.0 15.626554763834948 AGAAS(ph)PLNS(ph)PLSSAVPSLGK ddPTM_PC-9_Lapatinib_30min_R1 1 AGAASPLNSPLSSAVPSLGK 20 0 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 2 AGAAS(1)PLNS(0.987)PLS(0.011)S(0.002)AVPSLGK 116.09 0.0011328 0.0 4512.0 6916.5 6166.7 4960.5 9921.9 6146.4 9422.8 11738.0 7322.5 7133.0 True False 4447.658052600538 6900.485269198493 5659.697730150389 5325.3117177429085 9338.313349205935 5883.532799958204 9910.6664778855 12283.390331675757 6497.762940656594 8365.929545874938 0.5316394344718793 0.8248318649301769 0.6765174986372036 0.6365475215325841 1.1162314119427958 0.7032730514517957 1.1846461799062409 1.4682636596829142 0.7766934809844893 1.0 13.03031013296141 -6.577042850165437 1.06369061368162 1.1190923634805319 0.6669385803046046 0.3899601740642985 0.2173845378978673 0.503097826271458 1.218407932664302 0.10817961720266293 0.11814533457242846 2.648238834180171e-07 6.577042850165437 -0.45215378317592725 AGAAS(ph)PLNSPLSSAVPSLGK ddPTM_PC-9_AZD4547_30min_R2 1 AGAASPLNSPLSSAVPSLGK 20 0 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 AGAAS(0.902)PLNS(0.06)PLS(0.037)S(0.001)AVPSLGK 127.67 2.3820999999999998e-05 38862000.0 71594.0 85054.0 98930.0 90446.0 76223.0 99713.0 120580.0 106560.0 98479.0 106240.0 True False 94359.40275229015 112546.04217837719 97618.12356028632 69595.07207677029 65640.75215475197 93477.93034707186 131311.38640558775 90093.60050519874 103684.39889113679 102520.56993693928 0.9203948320842432 1.097789860587047 0.9521808513192184 0.6788400817472867 0.6402690913162871 0.9117968267692076 1.2808296567835877 0.8787855994227851 1.0113521506456058 1.0 16.645553878496052 -7.015319733838646 24.71826550869171 1.0417367435638505 0.8574650422721674 0.24502671628838668 0.1536723445000574 994.4141837426429 1604476.9108571394 0.06317631760005665 0.05062908343696687 9.653399201911332e-08 7.015319733838646 -0.18427170129168313 AGAAS(ph)PLNSPLSSAVPSLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AGAASPLNSPLSSAVPSLGK 20 0 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 AGAAS(0.784)PLNS(0.214)PLS(0.001)SAVPSLGK;AGAAS(0.857)PLNS(0.14)PLS(0.003)SAVPSLGK;AGAAS(1)PLNSPLSSAVPSLGK 169.43 2.5168e-08 59703100.0 101149.0 144031.0 162552.0 166851.0 184400.0 131455.0 163891.0 129600.0 127608.0 111863.0 True False 118271.5279161863 158329.44581228239 166427.85616189268 157502.8794082404 148268.1437264762 124561.26838669815 148366.0580119134 126198.1373225503 129474.02558938232 132142.87639297938 0.8950276484406082 1.1981686045748454 1.2594538631575816 1.1919135083743975 1.1220290323145528 0.9426256774997519 1.1227700051774865 0.9550127919665528 0.9798032941582097 1.0 17.01173912817505 -6.634131371548772 6.120525821848479 1.005447092363743 1.1501585345178023 0.2987563536053286 0.10106638174336846 0.2669914828774928 13.39514847761451 0.034183789397807814 0.03410798387258937 2.3220342882757773e-07 6.634131371548772 0.14471144215405918 AGAAS(ph)PLNSPLSSAVPSLGK ddPTM_PC-9_Lapatinib_30min_R1 2 AGAASPLNSPLSSAVPSLGK 20 0 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 AGAAS(0.996)PLNS(0.004)PLSSAVPSLGK;AGAAS(0.967)PLNS(0.029)PLS(0.001)S(0.003)AVPSLGK 221.51 3.8544e-29 56958000.0 166543.0 274500.0 286690.0 242150.0 306150.0 252150.0 276070.0 287680.0 268960.0 196670.0 True False 164168.06627975445 273864.4121152301 263119.4548554028 259958.51878872034 288142.8589140584 241366.13229035883 290363.5537791155 301046.6630274732 238666.89252563962 230664.14745369766 0.7117190429982566 1.1872864298089683 1.1407037364062833 1.1270001066849935 1.2491878867820094 1.0463963947358115 1.2588152818044753 1.3051298450614384 1.0346943604382575 1.0 17.815434255179227 -4.759462588679446 24.99669150618699 1.1617148778352213 0.7117184715868857 0.642322117919576 0.09774080247872131 30.416865084171086 384524.13164593285 0.02307502969626111 0.14636830730391379 1.7399525758807967e-05 4.759462588679446 -0.4499964062483356 AGAAS(ph)PLNSPLSSAVPSLGKEPFPPSS(ph)PLQK ddPTM_PC-9_AZD4547_30min_R2 1 AGAASPLNSPLSSAVPSLGKEPFPPSSPLQK 31 1 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 2 AGAAS(0.96)PLNS(0.033)PLS(0.003)S(0.004)AVPS(0.002)LGKEPFPPS(0.279)S(0.719)PLQK 67.71 0.0018823 0.0 11590.0 8488.3 14947.0 19486.0 15259.0 14619.0 11328.0 18890.0 12244.0 14393.0 True False 15275.37891302402 11231.976977246451 14748.793013803699 14993.803755698926 13140.551239512473 13704.871618984957 12336.170054756181 15970.984549016557 12891.192843378587 13889.105450888246 1.0998101329878749 0.8086897328962346 1.061896539410353 1.0795370377679745 0.9461049371377693 0.9867353709312138 0.888190394865729 1.149892957864696 0.9281514125558143 1.0 13.761666062876907 -7.7384430664014765 24.999822684893065 1.029266948849592 0.9806098985747785 0.041242932209667016 0.09775499714935725 776.6736341396694 844341.0389370542 0.04427352818086912 0.02554065045721782 1.8262361428153302e-08 7.7384430664014765 -0.048657050274813485 AGAAS(ph)PLNSPLSSAVPSLGKEPFPPSS(ph)PLQK ddPTM_PC-9_Lapatinib_30min_R1 2 AGAASPLNSPLSSAVPSLGKEPFPPSSPLQK 31 1 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 2 AGAAS(0.807)PLNS(0.113)PLS(0.035)S(0.037)AVPS(0.027)LGKEPFPPS(0.339)S(0.642)PLQK;AGAAS(0.866)PLNS(0.042)PLS(0.042)S(0.042)AVPS(0.009)LGKEPFPPS(0.386)S(0.611)PLQK 58.924 0.0035326 23356000.0 29307.0 23426.2 27235.0 24390.0 44637.0 65179.0 46796.0 45501.0 70879.0 41684.0 True False 28889.076805754426 23371.958073201444 24995.843430140234 26183.721962654876 42011.53941971854 62391.44610966997 49218.86790541348 47615.14256956706 62895.860631041025 48889.02385956132 0.5909113032966506 0.47806145895528135 0.5112772041009314 0.5355746524592161 0.8593245702839343 1.2761851471793695 1.006746791402497 0.9739434091862089 1.2865026884503925 1.0 15.577222979679114 -6.42741622738115 3.1530887915778294 1.1003635295925582 0.5226503010507492 0.8678265185396665 0.10622540944449056 0.08601538416418715 1.6364439756427323 0.03457343030755076 0.03896060889355552 3.7375221283291254e-07 6.42741622738115 -0.5777132285418091 AGAASPLNS(ph)PLSSAVPSLGK ddPTM_PC-9_AZD4547_30min_R2 1 AGAASPLNSPLSSAVPSLGK 20 0 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 AGAAS(0.197)PLNS(0.531)PLS(0.085)S(0.186)AVPSLGK 102.5 0.00022368 37831000.0 85903.0 98388.0 114120.0 143800.0 118410.0 120980.0 107310.0 137590.0 122830.0 122660.0 True False 113218.3671066009 130189.99691779539 112606.69423531658 110649.13168785303 101970.81540537877 113415.1014751214 116860.3821129841 116328.6270036626 129322.54303758501 118365.71073479817 0.9565132199499056 1.0998962124216014 0.9513455673629602 0.9348073103347104 0.8614894868822894 0.958175309141946 0.9872823927430571 0.9827899167884886 1.0925676214400972 1.0 16.852891682789817 -10.158662082848448 7.003956266184968 0.9999995713103502 0.9779525676388202 0.006181024692721304 0.06715741887387747 0.0 0.0 0.06854030477829427 0.016623465659584363 6.93965558804103e-11 10.158662082848448 -0.022047003671530008 AGADGGT(ph)PTDR ddPTM_PC-9_AZD4547_30min_R2 1 AGADGGTPTDR 11 0 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 AGADGGT(0.997)PT(0.003)DR 108.98 0.0051768000000000005 3865700.0 12493.0 12841.0 15791.0 17273.0 13754.0 16971.0 10565.0 14709.0 17902.0 15874.0 True False 16465.514129457217 16991.60213055872 15581.601022343892 13290.976715189743 11844.494511321487 15909.800687173794 11505.26453288304 12436.062029194512 18848.26317234266 15318.256091669555 1.0748948203321635 1.1092386776193912 1.0171915738383268 0.8676559939755613 0.7732273465360601 1.0386169673600074 0.7510818766856814 0.8118458103045783 1.2304444487380526 1.0 13.902964442405812 -5.564734941181349 4.137702887508269 0.9085767987674088 1.0879414942795915 0.19374139368138033 0.135619090827384 0.29945839766280863 11.079816144391462 0.03691452643435765 0.06972979631560088 2.7243635356538295e-06 5.564734941181349 0.1793646955121827 AGADGGT(ph)PTDR ddPTM_PC-9_Lapatinib_30min_R1 1 AGADGGTPTDR 11 0 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 AGADGGT(0.732)PT(0.268)DR 84.605 0.029138 4295700.0 5338.0 13511.0 15987.0 13304.0 18449.0 16931.0 15762.0 15745.0 14342.0 12105.0 True False 5261.879141130692 13479.716109613357 14672.61057160463 14282.420540842984 17363.866092129567 16206.9005980887 16578.07923594169 16476.570179948427 12726.652932044633 14197.333121101381 0.37062447547349603 0.9494540977966182 1.0334765301658555 1.00599319738544 1.2230371678975254 1.1415454198225803 1.167689670625663 1.1605398027506613 0.8964115178173225 1.0 13.793332333624292 -4.662708338201827 1.9667345608351525 1.0947947443923123 1.5839392016744318e-15 0.8347328932239724 0.09393994574120744 0.42856158056358573 1.3755971393101014 0.025570732611328927 0.9507896705409327 2.1741608031362825e-05 4.662708338201827 -1.0947947443923107 down AGADGGTPT(ph)DR ddPTM_PC-9_Lapatinib_30min_R1 1 AGADGGTPTDR 11 0 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 AGADGGT(0.283)PT(0.717)DR 100.38 0.010204000000000001 3243200.0 6755.6 16899.0 18881.0 15334.0 18085.0 14528.0 19160.0 14807.0 17145.0 17094.0 True False 6659.263905174689 16859.871403771464 17328.677062767685 16461.713512724476 17021.275856478016 13906.67130642209 20152.011049400004 15494.98727561108 15213.949555146095 20048.675123676745 0.33215481143241954 0.8409469104449988 0.8643302839649069 0.8210873492225829 0.8489975398113224 0.6936454015357266 1.005154252093258 0.7728683905557466 0.7588506203673769 1.0 14.291219281783 -4.7612535977331 24.999997184466707 0.8382414541120244 0.3321542528518455 0.731850443416332 0.09306351369605821 2.1672029810811186 290872.8097772653 0.02174146398836702 0.12233972781386433 1.7327918724959057e-05 4.7612535977331 -0.5060872012601789 AGAES(ph)PTMSVDGR ddPTM_PC-9_AZD4547_30min_R2 3 AGAESPTMSVDGR 13 0 O75362 O75362 ZNF217 Zinc finger protein 217 1 AGAES(0.449)PT(0.449)MS(0.102)VDGR;AGAES(0.497)PT(0.497)MS(0.006)VDGR;AGAES(0.484)PT(0.484)MS(0.031)VDGR 131.79 0.00047355 37031000.0 77423.0 90363.0 113320.0 130755.0 124734.0 97750.0 97272.0 124256.0 96202.0 97468.0 True False 102041.90350155823 119571.0726052239 111817.30275802739 100611.4548946122 107416.83716556452 91637.67704738889 105929.01955916718 105055.09031882464 101287.04131972457 94055.67498695041 1.0849095869623588 1.2712797247142564 1.188841638460851 1.0697010564069775 1.1420558853090776 0.974291844273118 1.1262374075127748 1.1169457912390754 1.0768838917351606 1.0 16.521227373043054 -5.75819385485363 24.69007304746209 1.0782449327764585 1.1906372955498472 0.3666033653622742 0.06523880108621186 72.76958264931297 553575.1016611706 0.01725355555988654 0.028351646948971486 1.7450430489027187e-06 5.75819385485363 0.11239236277338871 AGAES(ph)PTMSVDGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGAESPTMSVDGR 13 0 O75362 O75362 ZNF217 Zinc finger protein 217 1 AGAES(0.783)PT(0.213)MS(0.004)VDGR 113.99 0.00027446 16609000.0 60377.0 70542.0 79499.0 68007.0 90863.0 66470.0 67977.0 67635.0 58362.0 50922.0 True False 70597.6335998929 77544.94356416314 81394.55766163634 64196.788271668884 73059.04741550313 62984.19618625265 61537.72644913883 65859.6529152062 59215.433839943544 60153.75550166976 1.1736197185217012 1.289112257704519 1.3531084964325624 1.0672116435005774 1.2145384241799357 1.0470534326739471 1.0230072243358215 1.0948552150393678 0.9844012787913106 1.0 15.876367189677362 -6.447982638546745 0.9592248163720697 1.0230268784641423 1.2654753367800424 0.628678657360086 0.07349458713096707 0.3597971713001867 0.7153016207514173 0.03720847724011785 0.04769919904910375 3.5646538328123166e-07 6.447982638546745 0.24244845831590012 AGAES(ph)PTMSVDGR ddPTM_PC-9_Lapatinib_30min_R1 4 AGAESPTMSVDGR 13 0 O75362 O75362 ZNF217 Zinc finger protein 217 1 AGAES(0.5)PT(0.5)MSVDGR;AGAES(0.776)PT(0.224)MSVDGR;AGAES(0.497)PT(0.497)MS(0.006)VDGR;AGAES(0.426)PT(0.426)MS(0.148)VDGR 195.72 1.0962e-06 40856100.0 117553.0 132147.0 154974.0 124469.0 140989.0 137012.0 131274.0 129641.0 139701.0 109866.0 True False 115876.67266341999 131841.02174058743 142232.63593693983 133622.86547641212 132696.30421503904 131152.31615057169 138070.7253913848 135664.59413773858 123966.40226325252 128856.19171275703 0.8992712815983988 1.0231640403783164 1.1038090917198704 1.0369921980488204 1.0298015365132185 1.0178192790528306 1.0715102127119245 1.0528372159264079 0.9620523516603322 1.0 16.97540233673074 -4.771329635987709 4.805459309884801 1.0384681871934414 0.8905824727111542 0.5450779957788267 0.03662596515172901 0.12701982028315456 7.170161371503385 0.009052669812729609 0.06303034215714726 1.6930522607254427e-05 4.771329635987709 -0.14788571448228716 AGAESPT(ph)MSVDGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGAESPTMSVDGR 13 0 O75362 O75362 ZNF217 Zinc finger protein 217 1 AGAES(0.306)PT(0.694)MSVDGR 104.94 0.004906300000000001 17423000.0 68892.0 86359.0 89608.0 97513.0 89062.0 79289.0 80903.0 72407.0 74243.0 62847.0 True False 80554.0549209768 94932.15079325186 91744.59456023223 92049.6627514113 71610.94043691659 75130.94525969286 73239.28215300285 70506.39297155803 75328.66342104341 74240.66360342184 1.0850395323953432 1.2787082736808446 1.2357728245845532 1.2398820037913647 0.9645783989680818 1.011991833222649 0.9865116850818014 0.949700468037146 1.014655038961309 1.0 16.179921985665352 -6.261637776394669 24.999999770625358 0.9865258074495706 1.216620650467117 0.8221305691515189 0.05053264938218526 6.813393407405739 858547.7973909983 0.014895735504032916 0.01798902579919783 5.474723922426372e-07 6.261637776394669 0.23009484301754646 AGAESPT(ph)MSVDGR ddPTM_PC-9_Lapatinib_30min_R1 1 AGAESPTMSVDGR 13 0 O75362 O75362 ZNF217 Zinc finger protein 217 1 AGAES(0.375)PT(0.625)MSVDGR 167.73 0.00068149 9108500.0 31540.0 35261.0 43372.0 34879.0 33278.0 35350.0 31712.0 29973.0 40805.0 28676.0 True False 31090.23381627237 35179.3553209294 39806.1215807616 37444.11801293316 31320.653467065284 33838.162904874785 33353.892191992294 31365.655001816085 36209.11120430072 33632.6083916318 0.9244074516684825 1.0459895025472494 1.183557371383239 1.1133278030927185 0.9312585304819307 1.0061117624553357 0.9917129175235526 0.932596563328708 1.0766072848905168 1.0 15.037573051596912 -6.254755098117695 24.886226745821766 0.9872641206563229 1.0736709468756178 0.21481152527439362 0.071650644139352 761.6052285601154 2835528.200636335 0.022239462553868775 0.02804681873083706 5.56217824210855e-07 6.254755098117695 0.08640682621929496 AGAGADGGAVDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGAGADGGAVDR 12 0 A0A1B0GW30 A0A1B0GW30 0 86.624 0.041563 743160.0 2707.7 2359.8 3534.7 2293.6 4500.5 4578.3 3315.7 3816.4 3254.9 4589.6 False True 3166.0601304872716 2594.0653486251085 3618.9806534243976 2165.0970279515277 3618.659332109572 4338.205888363476 3001.6128924108107 3716.2235438100456 3302.4967548341774 5421.6581487463945 0.583965282137778 0.4784634658725049 0.667504397019422 0.39934222493392457 0.667445130775404 0.8001621956497873 0.5536337426779386 0.6854404025213795 0.6091303922579085 1.0 12.404518434603405 -14.522878745201165 0.16391344546108882 2.4931762868900305 0.5052638935611766 0.5901325124032661 0.1020697402455346 93.65794114586345 0.8673346908789535 45.43131595191417 0.405858057494816 3.0000000005469033e-15 14.522878745201165 -1.9879123933288538 AGAGMITQHSS(ph)NASPINR ddPTM_PC-9_AZD4547_30min_R2 1 AGAGMITQHSSNASPINR 18 0 Q9NWH9;Q9NWH9-3;H7C3F4;H0YKH2 Q9NWH9 SLTM SAFB-like transcription modulator 1 AGAGMIT(0.001)QHS(0.229)S(0.472)NAS(0.298)PINR 84.37100000000001 0.0059089 0.0 8208.7 7815.2 20195.0 48963.0 25579.0 22151.0 14673.0 28658.0 13448.0 19594.0 True False 10818.895848433163 10341.31056543435 19927.201104821415 37675.33682080912 22027.79737567922 20765.89446830396 15978.86857463255 24229.56459532643 14158.83382536387 18908.020023949437 0.5721855506144822 0.5469272061451042 1.0539020521229117 1.9925585425173267 1.1649975696967838 1.0982585401327736 0.8450841787978466 1.2814437770129592 0.7488268897235082 1.0 14.206710677200688 -5.311048047170232 4.9107065374338985 1.1810336369018155 0.5557966082355241 0.35348677757024927 0.3186252913063033 0.20613634744356718 11.309610782051017 0.08793284227193773 0.1974754493711313 4.885983014043096e-06 5.311048047170232 -0.6252370286662914 AGAGMITQHSSNAS(ph)PINR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGAGMITQHSSNASPINR 18 0 Q9NWH9;Q9NWH9-3;H7C3F4;H0YKH2 Q9NWH9 SLTM SAFB-like transcription modulator 1 AGAGMIT(0.001)QHS(0.07)S(0.188)NAS(0.741)PINR 63.93600000000001 0.011576000000000001 5518200.0 11963.0 19056.0 19627.0 14577.0 17137.0 16237.0 12793.0 10802.0 13505.0 11042.0 True False 13988.099619979781 20947.75374328336 20094.982115812003 13760.29794927164 13779.127868983827 15385.503136395117 11581.154426700708 10518.458945665061 13702.485076050123 13043.827191576087 1.0723922829193506 1.60595149227458 1.5405740831026697 1.0549279553594717 1.0563715439194572 1.1795236866010708 0.8878647544625555 0.8063936137131632 1.0504957536465531 1.0 13.671079612630736 -5.838490156641217 5.921013919156575 0.9975208843469487 1.425000764183612 0.5655024671584907 0.16123184055462636 0.14277004129874196 8.309961642357557 0.04697796420753046 0.07097870458642433 1.4504736491660159e-06 5.838490156641217 0.42747987983666325 AGAHLQGGAK ddPTM_PC-9_AZD4547_30min_R2 1 AGAHLQGGAK 10 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 85.73100000000001 0.0098347 7309000.0 179890.0 152130.0 97648.0 86876.0 74697.0 72196.0 59729.0 95358.0 140420.0 243780.0 False True 237091.2780555557 201303.04743570578 96353.12371793021 66848.08042082009 64326.61091407452 67681.57270704139 65044.76528959503 80622.61220884719 147842.3145268885 235245.3364008568 1.007846878849719 0.8557153587635271 0.4095856912280931 0.284163254598643 0.27344478703910335 0.2877063313668091 0.276497576040186 0.3427171541095577 0.628460129279528 1.0 17.84380659710137 -10.718324925306234 12.99492655188986 1.0007434616722355 0.4655378681087578 0.2723365589450024 0.25064997842725384 3.743531531043146e-10 0.0 0.26927020451573197 0.06530761735588428 1.9128242752996602e-11 10.718324925306234 -0.5352055935634776 AGAHLQGGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGAHLQGGAK 10 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 111.46 0.0013369000000000002 18976000.0 199128.0 370507.0 267435.0 216463.0 803950.0 622400.0 211772.0 595740.0 691210.0 1076580.0 False True 232836.43744272637 407288.4863645415 273811.66465288517 204335.27989251437 646421.7687033628 589760.2483274197 191711.42306349284 580102.4562387046 701317.6386091541 1271755.43179741 0.18308271513623628 0.32025692690685703 0.21530213892296807 0.160671835781917 0.5082909437939302 0.4637371569892916 0.1507455114955093 0.45614309303073197 0.5514563736660916 1.0 20.278389825435823 -14.522878737841365 0.15694769925499022 3.5518680647221346 0.13850289872709046 0.7738030740936629 0.11734955605386921 64.42976956413763 0.5849729203504825 50.746322295017116 0.5478933265222914 3.0000000513866004e-15 14.522878737841365 -3.413365165995044 AGAHLQGGAK ddPTM_PC-9_Lapatinib_30min_R1 2 AGAHLQGGAK 10 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 115.71 0.00092405 24953000.0 246734.0 384679.0 176669.0 348773.0 364572.0 204534.0 619650.0 958630.0 383799.0 432590.0 False True 243215.52791452614 383788.29941010824 162143.9567820614 374422.9298926209 343128.5917361297 195786.55761204154 651732.445029265 1003171.4494508696 340571.51503735903 507362.6051100584 0.47937219941892883 0.7564378918443465 0.31958200141078336 0.7379789643964796 0.6762985452223019 0.3858907921871203 1.2845496267662249 1.977227803837177 0.6712586059894607 1.0 18.952657664689312 -7.272537555255474 23.284614783647136 1.3146948717231774 0.5707717631166045 0.4842457290292099 0.3364667860473159 224.70085340285314 471431.7223944613 0.13299654525357046 0.09077360627383779 5.339031027494854e-08 7.272537555255474 -0.743923108606573 AGALHAQVER ddPTM_PC-9_AZD4547_30min_R2 1 AGALHAQVER 10 0 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 0 73.84100000000001 0.022580000000000003 1441300.0 7373.4 7972.7 9673.0 11905.0 11242.0 7313.5 8821.2 8777.6 7370.7 8973.0 False True 9717.987823752488 10549.719360353994 9544.729699774074 9160.486180416481 9681.242351045223 6856.185688860142 9606.26971107126 7421.223609181983 7760.30015441772 8658.858001168635 1.1223174952679567 1.218373064777152 1.1023081448484173 1.0579323715875864 1.1180738094721732 0.791811771013545 1.1094153189456113 0.8570672493047448 0.896226748766449 1.0 13.079961048102273 -6.295230487992383 1.1454596090975364 0.9324915468580224 1.1618854824815008 0.47936640639726924 0.0939245562680585 0.4013892397427527 1.092104555017865 0.03869863791805552 0.05543031073647866 5.067217104581319e-07 6.295230487992383 0.22939393562347843 AGALHAQVER ddPTM_PC-9_Lapatinib_30min_R1 2 AGALHAQVER 10 0 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 0 ; 94.40899999999999 0.006443300000000001 1878200.0 28809.0 24955.0 27696.0 25763.0 24234.0 28443.0 25089.0 23021.2 28716.0 20496.2 False True 28398.178377076438 24897.218230730625 25418.941789651686 27657.696962848622 22808.603765877142 27226.559193871384 26387.985658580204 24090.848995022472 25481.701687114335 24038.940860530212 1.1813406647920874 1.0357036266772313 1.0574068939695804 1.1505372521740376 0.9488189974012884 1.1326022786043355 1.0977183151154097 1.0021593353381675 1.060017653646006 1.0 14.553085712831416 -1.5228787452863153 0.09349309813435167 0.9655037448765508 1.3739750956731558 0.19590578303508255 0.06282015348539899 275.5880931184538 1.8506013672425565 1.0078490473183104 14.426109473660759 0.029999999999587072 1.5228787452863153 0.408471350796605 AGAPGALS(ph)PSYDGGLHGLQSK ddPTM_PC-9_AZD4547_30min_R2 4 AGAPGALSPSYDGGLHGLQSK 21 0 K7ENH8;A0A0A0MRB7;P15923-2;X6REB3;P15923;P15923-3 K7ENH8 TCF3 Transcription factor E2-alpha 1 AGAPGALS(0.983)PS(0.013)Y(0.004)DGGLHGLQSK;AGAPGALS(0.999)PS(0.001)YDGGLHGLQSK;AGAPGALS(0.995)PS(0.005)YDGGLHGLQSK;AGAPGALS(0.995)PS(0.005)YDGGLHGLQSK 125.08 1.0625e-06 293695000.0 327420.0 274399.0 521975.0 695250.0 612540.0 490789.0 417684.0 590720.0 413744.0 517599.0 True False 431532.7492409256 363093.11058509385 515053.2704475933 534970.8540054236 527499.3942100384 460099.8862446141 454857.0668388759 499437.7973951854 435613.6631648828 499478.0165548748 0.8639674518958845 0.726945127814655 1.0311830618695654 1.0710598590411624 1.056101323234283 0.9211614345274505 0.9106648376163385 0.9999194776179204 0.8721378093264379 1.0 18.930061656748407 -5.265348706484749 24.99879724263328 0.9837710859702535 0.7954562855579034 0.5456797180848588 0.06836452911388291 235.36178866419783 1505067.90547854 0.01879715319325622 0.04161767916245713 5.428143165520361e-06 5.265348706484749 -0.18831480041235016 AGAPGALS(ph)PSYDGGLHGLQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 AGAPGALSPSYDGGLHGLQSK 21 0 K7ENH8;A0A0A0MRB7;P15923-2;X6REB3;P15923;P15923-3 K7ENH8 TCF3 Transcription factor E2-alpha 1 AGAPGALS(0.948)PS(0.05)Y(0.002)DGGLHGLQSK;AGAPGALS(0.999)PS(0.001)YDGGLHGLQSK;AGAPGALS(0.99)PS(0.01)YDGGLHGLQSK;AGAPGALS(0.994)PS(0.006)YDGGLHGLQSK;AGAPGALS(0.911)PS(0.064)Y(0.024)DGGLHGLQSK 144.43 9.4949e-06 240595000.0 230591.0 236766.0 370945.0 345439.0 407154.0 373213.0 388015.0 393504.0 375326.0 292331.0 True False 269625.5019201507 260270.56374801826 379789.7356167463 326085.1727583487 327375.096479444 353641.053276063 351259.4102146703 383174.93695195235 380814.432702969 345328.2962090776 0.7807802166229294 0.7536902321796374 1.0997932685678447 0.944275856736981 0.9480112115725267 1.0240720414696411 1.0171752910801197 1.1095961181239566 1.1027605814045613 1.0 18.397609027938728 -3.800600798110249 0.5249873617893983 1.0557284033343317 3.1903440961025264e-10 0.6202839053843302 0.07371513357239268 7.145758930327326 0.6884790781730932 0.04107956354699177 5.794778937010133 0.00015827021848700316 3.800600798110249 -1.0557284030152974 AGAPGALS(ph)PSYDGGLHGLQSK ddPTM_PC-9_Lapatinib_30min_R1 2 AGAPGALSPSYDGGLHGLQSK 21 0 K7ENH8;A0A0A0MRB7;P15923-2;X6REB3;P15923;P15923-3 K7ENH8 TCF3 Transcription factor E2-alpha 1 AGAPGALS(0.992)PS(0.008)YDGGLHGLQSK;AGAPGALS(0.999)PS(0.001)YDGGLHGLQSK 157.49 6.198400000000001e-06 113658000.0 143369.0 113164.0 172433.0 136877.0 177888.0 161965.0 133118.0 140372.0 187970.0 136231.0 True False 141324.5317693451 112901.97571077559 158256.22435062827 146943.3911882868 167424.9775812642 155038.13450885582 140010.19868862364 146894.19557318042 166798.8391881486 159778.34683360282 0.8845036550323306 0.7066162464952435 0.9904735371648342 0.9196702438116808 1.0478577410468815 0.9703325737267543 0.8762776775656201 0.9193623446746494 1.0439389472583358 1.0 17.28571238187395 -5.275217599992865 24.988406501189683 0.9656157117241023 0.7955599479931215 0.5339672519487733 0.06540209403670276 518.4201410234266 940215.2996642111 0.016844465487376416 0.0353592141225781 5.3061851518838214e-06 5.275217599992865 -0.17005576373098086 AGAPPPSGS(ph)AVSTAPQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGAPPPSGSAVSTAPQQK 18 0 P78362;P78362-2 P78362 SRPK2 SRSF protein kinase 2;SRSF protein kinase 2 N-terminal;SRSF protein kinase 2 C-terminal 1 AGAPPPSGS(0.409)AVS(0.295)T(0.295)APQQK 66.663 0.01374 4000300.0 13095.0 15112.0 13859.0 16877.0 17690.0 17640.0 16765.0 16291.0 13412.0 11577.0 True False 15311.724861960643 16612.219488271312 14189.451120550186 15931.43640597225 14223.771488727545 16714.92734655477 15176.897831910994 15863.3785117413 13608.125126988838 13675.81845651843 1.119620365731199 1.2147148297624029 1.037557727580607 1.1649347683742253 1.0400672935189441 1.2222250097644272 1.1097615751602121 1.1599582549430667 0.9950501441837051 1.0 13.739339556101209 -8.267826474518623 24.613736715721185 0.9975250356810594 1.1331926900948404 0.4594230499932769 0.05904272319505658 372.90201955069006 1437013.5915898823 0.04854903602882951 0.013798384803266919 5.397262309327181e-09 8.267826474518623 0.13566765441378092 AGAPVGGS(ph)PGLAK ddPTM_PC-9_AZD4547_30min_R2 4 AGAPVGGSPGLAK 13 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 AGAPVGGS(1)PGLAK;AGAPVGGS(1)PGLAK;AGAPVGGS(1)PGLAK;AGAPVGGS(1)PGLAK 165.51 6.186e-05 141037000.0 183457.0 203392.0 234258.0 274982.0 260049.0 226069.0 237970.0 281360.0 210627.0 229298.0 True False 241792.50985734697 269134.48645265965 231151.5858585417 211589.1483295494 223945.6851224835 211932.86969233965 259148.86899102424 237882.2770095976 221760.31321645732 221270.34681287897 1.0927470098911307 1.216315201423071 1.0446568606593225 0.9562471943359105 1.0120908126558277 0.9578005943632577 1.1711866172929981 1.075075266234236 1.0022143337805345 1.0 17.75545059809061 -5.37271849166126 6.630071115362183 1.0287574041384848 1.15363175889323 0.38116037800094904 0.06499487884130817 0.24594909083566271 12.709024941906184 0.01781687590449177 0.03750374156758469 4.239176591266614e-06 5.37271849166126 0.12487435475474529 AGAPVGGS(ph)PGLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 AGAPVGGSPGLAK 13 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 AGAPVGGS(1)PGLAK;AGAPVGGS(1)PGLAK;AGAPVGGS(1)PGLAK;AGAPVGGS(1)PGLAK;AGAPVGGS(1)PGLAK 170.26 7.8081e-05 132331600.0 244669.0 258916.0 268401.0 293060.0 301471.0 256383.0 317550.0 263497.0 230504.0 190389.0 True False 286086.6292669756 284619.46936376765 274800.6977564603 276640.7983133399 242399.9216776813 242937.82414352355 287469.3651370908 256580.48294814897 233874.68492927516 224905.0185815055 1.272033105669885 1.2655096411760223 1.2218522267295366 1.2300339052375808 1.0777879622541 1.0801796495060558 1.278181193777639 1.1408392954787014 1.0398820195491505 1.0 17.778956328535507 -1.5228787469997078 0.08649611509712368 0.8738208897698476 1.9934638220884773 0.5872266835437954 0.06421612258059624 133.58461998574222 0.8381747194228619 1.4926625892123206 17.774836375081012 0.02999999988123011 1.5228787469997078 1.1196429323186297 AGAPVGGS(ph)PGLAK ddPTM_PC-9_Lapatinib_30min_R1 4 AGAPVGGSPGLAK 13 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 AGAPVGGS(1)PGLAK;AGAPVGGS(1)PGLAK;AGAPVGGS(1)PGLAK;AGAPVGGS(1)PGLAK 154.23 6.0743000000000004e-05 128656000.0 176996.0 202771.0 207339.0 209463.0 183787.0 194136.0 185536.0 179223.0 193577.0 146294.0 True False 174472.0045829091 202301.49620771332 190292.3877716856 224867.6077680839 172977.0099991443 185833.25583311927 195142.14624537987 187550.35486572888 171774.31980382127 171580.72297549795 1.016850853390005 1.1790455984767145 1.1090545865042176 1.3105645195363549 1.008137784941294 1.0830660496730544 1.1373197574954066 1.0930735785074843 1.001128313396552 1.0 17.388527950177163 -8.18235790792821 3.04643314620896 0.9964756345933584 1.1237623091386013 0.25527423045939446 0.08055849137126243 0.3607793207115473 6.0781434353593955 0.06830387699020318 0.021101103733991784 6.571160759465716e-09 8.18235790792821 0.1272866745452429 AGASIPSSGAAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 AGASIPSSGAASPR 14 0 Q9P270 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 AGASIPS(0.085)S(0.397)GAAS(0.518)PR;AGASIPSSGAAS(1)PR;AGASIPSSGAAS(1)PR 168.0 0.00037072 45535000.0 76986.0 70123.0 111704.0 136721.0 129604.0 111279.0 93707.0 143168.0 110892.0 119823.0 True False 101465.94659172285 92788.88841999616 110222.73197390298 105202.08576839321 111610.72172788352 104320.70653868448 102046.74146548705 121044.67527335115 116753.52472949513 115628.03324128277 0.8775203014998303 0.8024774427008733 0.9532526748413989 0.9098320088941271 0.9652565956473871 0.9022094695755732 0.8825432605304682 1.0468454048748317 1.0097337250895184 1.0 16.819131686420427 -5.2965426379152625 0.2541532933976825 1.024715356632236 0.7391810186811494 0.49409498254040574 0.04973534080808056 6.642358895906057 0.4563488450910442 0.07841155303667358 0.588033484064586 5.0519304395160835e-06 5.2965426379152625 -0.2855343379510866 AGASIPSSGAAS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AGASIPSSGAASPR 14 0 Q9P270 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 AGASIPSSGAAS(1)PR;AGASIPSSGAAS(1)PR;AGASIPSS(0.006)GAAS(0.993)PR;AGASIPSSGAAS(1)PR 177.93 8.1053e-05 52552000.0 89697.0 78120.0 109319.0 104392.0 132267.0 132746.0 105606.0 108709.0 110583.0 82865.0 True False 104880.93050349651 85875.23732290581 111925.57955461617 98543.25468343023 106350.23083660427 125784.56607402267 95602.23515877085 105855.50393670647 112200.06717251759 97887.76854102078 1.0714406106779846 0.8772826125556126 1.1434072021747306 1.0066963028392537 1.086450661014274 1.2849875724903412 0.9766514916386908 1.0813966393804018 1.146211307549616 1.0 16.57884098026043 -6.3453182814858256 5.718208934205226 1.1043876555873229 1.0228357083511483 0.10587762613133711 0.10030082158569058 0.4928283898558337 26.234320754331744 0.03104210822700339 0.03534627083993388 4.5152491393249184e-07 6.3453182814858256 -0.08155194723617454 AGASIPSSGAAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 AGASIPSSGAASPR 14 0 Q9P270 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 AGASIPSSGAAS(1)PR;AGASIPSSGAAS(1)PR;AGASIPSSGAAS(1)PR 203.85 1.1669e-10 46813000.0 159338.0 139528.0 166760.0 132643.0 156662.0 139559.0 129730.0 126348.0 151623.0 125621.0 True False 157065.81090098945 139204.9314885747 153049.6365122151 142398.00870407678 147447.4491693426 133590.3868979186 136446.784626235 132218.58933605123 134545.62107902678 147334.4224705392 1.0660496594568465 0.9448228672862238 1.038790758777493 0.9664951768657492 1.000767143868406 0.9067153802746344 0.9261025518562623 0.8974046059228927 0.9131988222638898 1.0 17.16873500817651 -6.7547865874946895 24.884262753099083 0.9221106998615156 1.0000492164571417 0.4452507746516544 0.04128294171190772 126.45939382537028 473011.53859343193 0.01277740953032562 0.012496687061902706 1.7587876707011608e-07 6.7547865874946895 0.07793851659562612 AGAVPSS(ph)PSTPAPPSAK ddPTM_PC-9_AZD4547_30min_R2 2 AGAVPSSPSTPAPPSAK 17 0 Q9C0C6 Q9C0C6 CIPC CLOCK-interacting pacemaker 1 AGAVPS(0.295)S(0.695)PS(0.008)T(0.002)PAPPSAK;AGAVPS(0.136)S(0.781)PS(0.041)T(0.041)PAPPS(0.002)AK 199.33 1.943e-12 5887200.0 30791.0 27892.0 40106.0 57909.0 49442.0 46268.0 35954.0 47293.0 35834.0 46161.0 True False 40581.89750741354 36907.54354221199 39574.16823520514 44558.974735131305 42577.83173104235 43374.85464581683 39153.83634787289 39984.95353502591 37728.11208343911 44544.917440314915 0.911033173690099 0.828546681934339 0.8884104070510399 1.0003155757294921 0.9558404006044409 0.9737329674913903 0.878974271314669 0.8976322290551142 0.8469678304823544 1.0 15.442973209681396 -5.535578550308194 24.947006989039874 0.9328959941896641 0.8669620669351534 0.2283526640779857 0.05118123742911826 315.8785312770989 620497.1388027156 0.014466337711541318 0.025075588528180565 2.913543118155492e-06 5.535578550308194 -0.06593392725451064 AGAVPSS(ph)PSTPAPPSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGAVPSSPSTPAPPSAK 17 0 Q9C0C6 Q9C0C6 CIPC CLOCK-interacting pacemaker 1 AGAVPS(0.043)S(0.863)PS(0.029)T(0.064)PAPPS(0.002)AK;AGAVPS(0.146)S(0.829)PS(0.008)T(0.014)PAPPS(0.003)AK 155.26 6.7799e-14 0.0 37023.0 39737.0 43893.0 41253.0 64427.0 61820.0 69316.0 72017.0 65521.0 54448.0 True False 43290.262662418376 43681.826747315885 44939.575585129474 38941.72815403052 51802.991843089265 58578.05037210978 62749.886675618305 70126.63005831896 66479.12067144628 64318.99138986919 0.6730556827300774 0.6791435282705033 0.6986983877394548 0.605446809916304 0.8054074033761776 0.910742676560944 0.9756043327119394 1.0902943056623324 1.0335846261718171 1.0 15.972957162803807 -6.8039565483917945 1.4749742939104837 1.0392358653392917 0.665278705486453 0.9454525903221378 0.03897764478671355 0.08243646810632727 0.37297139090865794 0.018161632076409907 0.015869891939381257 1.5705199286023424e-07 6.8039565483917945 -0.3739571598528387 AGAVPSS(ph)PSTPAPPSAK ddPTM_PC-9_Lapatinib_30min_R1 2 AGAVPSSPSTPAPPSAK 17 0 Q9C0C6 Q9C0C6 CIPC CLOCK-interacting pacemaker 1 AGAVPS(0.039)S(0.953)PS(0.006)T(0.002)PAPPSAK;AGAVPS(0.004)S(0.995)PS(0.001)TPAPPSAK 224.06 5.936799999999999e-82 0.0 35481.0 25336.0 31279.0 32917.0 48262.0 41900.0 43984.0 42086.0 52573.0 38788.0 True False 34975.03443358149 25277.3360486392 28707.36136043167 35337.825987893026 45423.324046742724 40108.034673670576 46261.27630463517 44041.46920249667 46651.67512176701 45492.45411823879 0.76880957757694 0.5556379962035294 0.6310356721099015 0.7767843408941401 0.9984804057544051 0.881641482110997 1.0168999936648426 0.9681049320405779 1.0254816106538307 1.0 15.473339643343948 -6.067266377599961 2.705070753025323 0.9783157972981349 0.6425849632946914 0.8517631038590958 0.06246069979443597 0.09562887418751174 1.3791136746870645 0.019030593831277424 0.02723151830723894 8.565123361697617e-07 6.067266377599961 -0.3357308340034435 AGCFS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 AGCFSPK 7 0 Q6P4F7-3;Q6P4F7;H3BQ41;H3BR51;Q6P4F7-2 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 1 AGCFS(1)PK;AGCFS(1)PK 80.165 0.025804 14442600.0 73094.0 65980.0 86067.0 88905.0 83093.0 82276.0 71505.0 81798.0 79146.0 91710.0 True False 96336.37155035198 87306.7446907768 84925.6953448211 68409.32581855754 71556.97123958376 77131.26871356508 77868.80647646009 69157.99863104601 83329.49598023857 88499.26081435154 1.0885556632211952 0.9865251289942825 0.9596203918920085 0.7729931887460906 0.8085601007413123 0.8715470389675507 0.8798808686075764 0.7814528392064373 0.9415840902337276 1.0 16.433377784757255 -5.282772790447315 1.9767525955080578 0.8559289160445134 1.0670307269473367 0.4904207607849337 0.07040020995490709 0.2852853993160964 2.014465477917675 0.019116723003736756 0.07388610931465037 5.21467455531905e-06 5.282772790447315 0.21110181090282332 AGCFS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGCFSPK 7 0 Q6P4F7-3;Q6P4F7;H3BQ41;H3BR51;Q6P4F7-2 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 1 AGCFS(1)PK;AGCFS(1)PK 70.816 0.043012 13821000.0 119850.0 124983.0 103906.0 133737.0 126475.0 116518.0 130049.0 129114.0 106646.0 98238.0 True False 140138.23785459972 137390.48625612826 106383.51310569924 126244.14947120383 101693.13165838427 110407.59096178389 117729.81724677575 125724.89430759134 108205.49599559011 116047.77174841975 1.2075909407240129 1.1839131780485836 0.9167217216055499 1.0878636234816195 0.8763040438108977 0.9513977674740431 1.014494423055382 1.0833891285750032 0.93242200488062 1.0 16.824359295969984 -5.2455409488318745 22.184942313504525 0.9857581241542303 1.1957523532173735 0.6328900963663158 0.0648366170462169 115.43647107967136 161078.13288661526 0.016318166285537804 0.04271841736884776 5.681448196990897e-06 5.2455409488318745 0.20999422906314325 AGCFS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 AGCFSPK 7 0 Q6P4F7-3;Q6P4F7;H3BQ41;H3BR51;Q6P4F7-2 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 1 AGCFS(1)PK 88.177 0.017446 9682800.0 46411.0 56005.0 47517.0 46142.0 43634.0 34052.0 45132.0 33087.0 41353.0 33499.0 True False 45749.170629264954 55875.32386343694 43610.33568092432 49535.43660519974 41067.53390774467 32595.675339088997 47468.71412742797 34624.34281003199 36695.389673604936 39289.25751538829 1.1644193227969892 1.4221527052668899 1.1099811612332864 1.2607883105400595 1.0452611350993306 0.8296332738362988 1.2081855735969573 0.8812674252362949 0.9339802275273992 1.0 15.261847283691463 -6.357866896438782 3.99506526073205 0.974594231331012 1.243750845494999 0.5279326090212637 0.11999321752381421 0.18465875588648073 5.300562639051387 0.03720686294749837 0.0427919967400621 4.3866512025928714e-07 6.357866896438782 0.26915661416398706 AGDGS(ph)SVKEVETYHR ddPTM_PC-9_AZD4547_30min_R2 1 AGDGSSVKEVETYHR 15 1 Q6PL18 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 AGDGS(0.5)S(0.5)VKEVETYHR 71.933 0.008709399999999999 4890200.0 27135.0 22905.0 41295.0 50667.0 53347.0 39151.0 38283.0 44746.0 40312.0 43568.0 True False 35763.36555693762 30308.593318312243 40747.40131832633 38986.50594734665 45940.68988624888 36702.88178089333 41690.11283600202 37831.53386078848 42442.81002142091 42042.69758106713 0.8506439313980355 0.7209003004593348 0.9691909335683516 0.9273074324541736 1.0927150856023358 0.872990647427475 0.9916136507562283 0.89983602474226 1.0095168117978701 1.0 15.359567619305562 -5.274162627434302 24.606685512497407 0.9669276742023147 0.7857721204703212 0.5606859140718049 0.06531196959838392 368.00009539023796 711710.6196817624 0.01603286141445031 0.03374463816216865 5.3190904144472145e-06 5.274162627434302 -0.18115555373199355 AGDGS(ph)SVKEVETYHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGDGSSVKEVETYHR 15 1 Q6PL18 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 AGDGS(0.5)S(0.5)VKEVETYHR;AGDGS(0.5)S(0.5)VKEVETYHR 73.877 0.007040100000000001 6263500.0 49178.0 39283.0 56445.0 60420.0 62347.0 60929.0 54340.0 54782.0 52998.0 37073.0 True False 57502.86409022532 43182.75662769737 57790.86286885455 57034.86328428296 50130.55291168437 57733.77598062562 49192.52181246904 53344.030546326896 53772.99548763458 43794.04143029347 1.313029403366484 0.9860418270926404 1.3196056125772195 1.3023429996764462 1.144688895439729 1.31830208163181 1.123269746428136 1.218065946967558 1.2278609996116596 1.0 15.41844697120813 -10.676066293889622 3.7933749927491607 0.999870206112079 1.2138805779729858 0.2874453048081371 0.1024006839197056 69794656.08473851 111305254.40225129 108316.56378477637 0.024354036177454706 2.108306298058644e-11 10.676066293889622 0.21401037186090677 AGDGS(ph)SVKEVETYHR ddPTM_PC-9_Lapatinib_30min_R1 1 AGDGSSVKEVETYHR 15 1 Q6PL18 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 AGDGS(0.5)S(0.5)VKEVETYHR 62.081 0.018747999999999997 5958100.0 38578.0 28031.0 29304.0 29141.0 29646.0 23558.0 27417.0 21348.0 29953.0 24598.0 True False 38027.87064566124 27966.09594171951 26894.7382367112 31284.126351526247 27902.28056627854 22550.479256380208 28836.518107588694 22339.906014705568 26579.37772092684 28849.731525225245 1.3181360323027942 0.9693710985582964 0.93223530392979 1.0843818884128071 0.967159106554656 0.7816530020968416 0.9995419916603038 0.7743540349819997 0.9213041617973713 1.0 14.816270272803973 -2.219513143576532 1.173743150821555 0.9200039744112563 199.9991831996514 0.6079056564051275 0.09146879237725869 519.0527265793226 1.9029696054455074 0.02800518999844476 276816.4117830345 0.006032354512099635 2.219513143576532 199.07917922524015 AGDLLEDS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 AGDLLEDSPK 10 0 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 AGDLLEDS(1)PK;AGDLLEDS(1)PK;AGDLLEDS(1)PK;AGDLLEDS(1)PK 152.4 0.0001188 967450000.0 1650140.0 2198080.0 1083980.0 919170.0 1013980.0 1359130.0 1670280.0 1256170.0 1476460.0 1148750.0 True False 2174850.1949557825 2908566.37420283 1069605.7169400507 707269.5575349369 873206.3795688357 1274143.3862446812 1818931.6842388895 1062057.7904149343 1554502.661347171 1108532.6121522859 1.9619180988578893 2.6237986526672095 0.9648843030998825 0.6380232297917953 0.787713748784937 1.1493963932832356 1.6408463443464412 0.9580753680786009 1.4023066568416118 1.0 20.080219783100247 -5.268074814471179 24.9754409483011 1.0642068674548189 2.2928584010040316 0.7151837887975706 0.30926644484189936 247.92238547594528 933169.954478674 0.08527606937675253 0.18429710663435886 5.3941769081283175e-06 5.268074814471179 1.2286515335492127 AGDLLEDS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 AGDLLEDSPK 10 0 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 AGDLLEDS(1)PK;AGDLLEDS(1)PK;AGDLLEDS(1)PK;AGDLLEDS(1)PK;AGDLLEDS(1)PK 149.41 0.00011874 539299000.0 1752814.0 2863410.0 1308486.0 1538466.0 1482470.0 936011.0 1676445.0 956569.0 891722.0 1090678.0 True False 2049530.7905454545 3147670.4211825673 1339685.2687007901 1452270.7377940705 1191990.6454999407 886924.9354068082 1517639.993189268 931460.0773186332 904761.7472777161 1288409.287597701 1.5907451229002703 2.4430671615628796 1.0397978977617397 1.1271812084666797 0.9251645862647131 0.6883875674790586 1.177917613446406 0.7229535569829552 0.7022316246762599 1.0 20.297159534973474 -5.357608419240013 5.9161198423741554 0.9128595356851762 2.0102705333954054 0.7544094205335841 0.25015508290139193 0.09378915621701561 4.662985169734842 0.06334268274288953 0.1346158391002355 4.389262764201799e-06 5.357608419240013 1.097410997710229 AGDLLEDS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 5 AGDLLEDSPK 10 0 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 AGDLLEDS(1)PK;AGDLLEDS(1)PK;AGDLLEDS(1)PK;AGDLLEDS(1)PK;AGDLLEDS(1)PK 142.97 0.00012790000000000002 925861100.0 882165.0 1450127.0 719704.0 953162.0 1030952.0 858085.0 1201106.0 1065525.0 722074.0 948127.0 True False 869585.1653307504 1446769.320027034 660532.7152577809 1023260.7131352202 970313.4302896166 821386.7048438339 1263293.3916232071 1115033.1813902543 640746.4223436891 1112009.4886501827 0.7819943752335242 1.3010404450623896 0.5939991717692725 0.9201906310865292 0.8725765743846624 0.738650805795621 1.1360455144646842 1.0027191249453653 0.5762058947189936 1.0 20.084737667790414 -5.259391154932557 24.999803240912055 0.8639766415745037 1.0415173682733136 0.11550884292036079 0.20521163274487886 392.3034075966105 4788207.811472421 0.050902149345170164 0.12150190372028867 5.5031182514635965e-06 5.259391154932557 0.17754072669880994 AGDLLEDS(ph)PKRPK ddPTM_PC-9_AZD4547_30min_R2 2 AGDLLEDSPKRPK 13 2 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 AGDLLEDS(1)PKRPK;AGDLLEDS(1)PKRPK 97.073 0.0096597 619346000.0 439880.0 398060.0 433450.0 534890.0 521910.0 448580.0 458190.0 468780.0 469960.0 445840.0 True False 579752.6899276108 526725.1105124374 427702.1697888017 411579.37446812063 449451.8053223635 420530.22168713744 498968.02236835676 396340.8224927465 494801.126157645 430231.2773031349 1.3475372910164438 1.22428363138581 0.9941215163848925 0.956646799479731 1.044674873802088 0.9774515333315429 1.159766964168881 0.921227357009403 1.1500817171156412 1.0 18.714752885227234 -5.079756110562772 3.1737983667993555 1.0241296633299743 1.3352354366269754 0.6774950829317535 0.07395153201563041 0.13514129136372094 2.526594475822781 0.01826844693258864 0.07100796173212574 8.322310010063023e-06 5.079756110562772 0.31110577329700106 AGDLLEDS(ph)PKRPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGDLLEDSPKRPK 13 2 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 AGDLLEDS(1)PKRPK 153.41 0.0019161999999999998 15779000.0 51861.0 47516.0 35895.0 58249.0 60822.0 53394.0 57561.0 57542.0 47558.0 50191.0 True False 60640.04299855982 52233.074457695904 36750.872932545564 54985.497375806 48904.36571438025 50593.92464523502 52108.405374448485 56031.58347078867 48253.44577910347 59290.230988262585 1.022766178977519 0.8809726929219798 0.6198470189772235 0.9273955668462689 0.8248300757010311 0.8533264890678343 0.8788700011096963 0.9450390483700593 0.8138515397023159 1.0 15.855506796870381 -7.448085606510967 3.3581549396347095 0.9102331455673178 0.8473761324603564 0.06564220315632652 0.10453899822857068 0.7908686027190008 17.250492325807596 0.05032255240455499 0.030801874098267203 3.563808780307104e-08 7.448085606510967 -0.06285701310696146 AGDLLEDS(ph)PKRPK ddPTM_PC-9_Lapatinib_30min_R1 2 AGDLLEDSPKRPK 13 2 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 AGDLLEDS(1)PKRPK;AGDLLEDS(1)PKRPK 174.47 0.0023501999999999998 79077000.0 255820.0 190878.0 201333.0 196744.0 200509.0 171116.0 166366.0 182449.0 180693.0 156949.0 True False 252171.9598883574 190436.03371850972 184780.1779078548 211213.21007874448 188715.45483586122 163797.76757087864 174979.6174449102 190926.2466028211 160341.45155835585 184077.42552860273 1.3699233307083267 1.0345431177758349 1.0038176999555162 1.1474150590286547 1.0251960787366499 0.8898308258088228 0.9505761879406616 1.037206197634235 0.8710544006029751 1.0 17.48995318599775 -2.0072656333069254 1.0824731977164215 0.9840326388379385 199.99998133077096 0.6952544920685748 0.0745040486579883 508.2417395539146 1.5113834823132641 0.023990887188492606 249985.37880536952 0.009834094259937786 2.0072656333069254 199.01594869193303 AGDNIPEEQPVAS(ph)TPTTVSDGENKKDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGDNIPEEQPVASTPTTVSDGENKKDK 27 2 Q9Y320-2;Q9Y320 Q9Y320-2 TMX2 Thioredoxin-related transmembrane protein 2 1 AGDNIPEEQPVAS(0.228)T(0.228)PT(0.191)T(0.191)VS(0.161)DGENKKDK 49.25 0.0071839 8929600.0 21176.0 19098.0 16046.0 19538.0 27950.0 19159.0 20461.0 20979.0 16739.0 17780.0 True False 24760.678554935374 20993.923225715047 16428.597494793867 18443.349203050653 22473.39814075379 18154.268312508095 18522.785955188236 20428.323479087885 16983.77620792323 21003.37325359745 1.1788905646712904 0.9995500709448762 0.7821885225974349 0.8781136715690031 1.069989942539566 0.8643501257303343 0.8818957665295817 0.9726210753117446 0.8086213582389322 1.0 14.35833343055593 -4.86382498553143 3.582469347155199 0.9076248078395227 1.1882392030412254 0.49726569783554975 0.08303280297567571 0.2036496241670999 4.390068544339006 0.020764450580971414 0.13306648296423385 1.3682801118355553e-05 4.86382498553143 0.2806143952017027 AGDNIPEEQPVASTPT(ph)TVSDGENKKDK ddPTM_PC-9_AZD4547_30min_R2 1 AGDNIPEEQPVASTPTTVSDGENKKDK 27 2 Q9Y320-2;Q9Y320 Q9Y320-2 TMX2 Thioredoxin-related transmembrane protein 2 1 AGDNIPEEQPVAS(0.012)T(0.009)PT(0.36)T(0.36)VS(0.258)DGENKKDK 80.813 9.4019e-06 39494000.0 142970.0 130780.0 153040.0 120460.0 123960.0 78864.0 172970.0 109240.0 115610.0 110040.0 True False 188431.48603926215 173052.07745771142 151010.58960544044 92689.80808844765 106750.29370535206 73932.62161294401 188363.99491271 92359.46808547204 121720.9085775073 106187.53309356903 1.774516090068901 1.6296835646913796 1.4221122311258025 0.8728878559291172 1.005299686275668 0.6962457781912776 1.7738805057909175 0.8697769445692636 1.1462824780970358 1.0 16.696254871465335 -5.501438441428153 3.1027360435622597 1.0607633446953024 1.6969547205788456 0.48109194709061587 0.2733873863843324 0.21867067051849368 4.251216950546697 0.07564848695546966 0.16481077211220055 3.151821099800703e-06 5.501438441428153 0.6361913758835431 AGDNIPEEQPVASTPT(ph)TVSDGENKKDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGDNIPEEQPVASTPTTVSDGENKKDK 27 2 Q9Y320-2;Q9Y320 Q9Y320-2 TMX2 Thioredoxin-related transmembrane protein 2 1 AGDNIPEEQPVAS(0.009)T(0.008)PT(0.328)T(0.328)VS(0.328)DGENKKDK 53.998000000000005 0.0024222 24416000.0 96335.0 91694.0 65465.0 81958.0 120130.0 68096.0 92599.0 83780.0 72269.0 77595.0 True False 112642.6127970203 100796.77433546515 67025.9338773951 77366.15897142104 96591.38886042032 64524.92588384322 83827.35236129581 81580.8637722477 73325.79740548428 91662.3592583179 1.2288862484935281 1.0996528471562153 0.7312263661958148 0.8440341225932437 1.0537737588469842 0.703941360509853 0.9145231809390603 0.8900148810521114 0.7999553797087143 1.0 16.48404179865107 -5.070241030897288 4.780454777177948 0.8656685978399933 1.2039697102535487 0.5814515825359234 0.10330467264028959 0.12672875340918768 5.43029782865358 0.025573948172346525 0.07759457571705605 8.506657926283293e-06 5.070241030897288 0.3383011124135554 AGDNIPEEQPVASTPT(ph)TVSDGENKKDK ddPTM_PC-9_Lapatinib_30min_R1 1 AGDNIPEEQPVASTPTTVSDGENKKDK 27 2 Q9Y320-2;Q9Y320 Q9Y320-2 TMX2 Thioredoxin-related transmembrane protein 2 1 AGDNIPEEQPVAS(0.078)T(0.078)PT(0.417)T(0.417)VS(0.009)DGENKKDK 81.477 7.5018e-06 48987000.0 185030.0 167780.0 65884.0 55276.0 52782.0 59918.0 60438.0 53842.0 82593.0 26055.0 True False 182391.43826965394 167391.5157183722 60467.27183959455 59341.18143533047 49677.466533404666 57355.44681567998 63567.18391459481 56343.69587988462 73290.50659715249 30558.572033894798 5.968585118026783 5.477727019858969 1.97873355379714 1.9418833239167959 1.6256475099132144 1.8769020604779163 2.0801752072736805 1.8437934801858415 2.39836162880453 1.0 14.899289509056905 -5.244970575313426 4.386672779198157 1.8625082743602481 5.842993516013175 0.9537482011657868 0.3424764983512698 0.03345690523656774 1.6531613630392012 0.08425927707253454 0.22253697473888717 5.688914735537805e-06 5.244970575313426 3.980485241652927 AGDNIPEEQPVASTPTT(ph)VSDGENKKDK ddPTM_PC-9_AZD4547_30min_R2 1 AGDNIPEEQPVASTPTTVSDGENKKDK 27 2 Q9Y320-2;Q9Y320 Q9Y320-2 TMX2 Thioredoxin-related transmembrane protein 2 1 AGDNIPEEQPVAS(0.023)T(0.023)PT(0.097)T(0.428)VS(0.428)DGENKKDK 45.611000000000004 0.016883000000000002 33696000.0 60936.0 51510.0 52163.0 39732.0 49641.0 28996.0 60042.0 47056.0 46022.0 40579.0 True False 80312.38045246188 68159.60016704939 51471.28453730125 30572.401253280794 42749.20401603239 27182.875536225994 65385.62168323367 39784.57643930773 48454.62896422483 39158.34156128632 2.0509648072497093 1.7406150886235439 1.3144398481928576 0.7807378973246925 1.0917010861945224 0.6941784164603181 1.6697750485908427 1.0159923748824067 1.2374024800919874 1.0 15.257032044593881 -5.218153283437491 2.334047865032996 1.0797206229311087 2.012458009175525 0.6289231536586048 0.2536125005771389 0.20853909191028916 2.102916843125512 0.06944998747983883 0.264457495250076 6.05127258507052e-06 5.218153283437491 0.9327373862444162 AGDNIPEEQPVASTPTTVS(ph)DGENKK ddPTM_PC-9_AZD4547_30min_R2 2 AGDNIPEEQPVASTPTTVSDGENKK 25 1 Q9Y320-2;Q9Y320 Q9Y320-2 TMX2 Thioredoxin-related transmembrane protein 2 1 AGDNIPEEQPVASTPT(0.01)T(0.043)VS(0.947)DGENKK;AGDNIPEEQPVAS(0.001)T(0.001)PT(0.041)T(0.099)VS(0.858)DGENKK 139.57 8.0185e-13 8700000.0 94019.0 96554.0 99415.0 53638.0 57763.0 60508.0 109559.0 80746.0 89683.0 66908.0 True False 123915.08628331349 127763.1922836202 98096.69214339288 41272.58779883909 49743.604511957456 56724.425194715215 119309.53875609425 68268.56105849074 94423.46028852678 64565.571285210164 1.9192130390349127 1.9788130073107015 1.5193343788450857 0.6392352298181132 0.7704354429425155 0.8785553053366835 1.8478817174722981 1.0573523892001682 1.4624428841715533 1.0 15.978477451950054 -5.508589983960571 5.009333954157975 1.1013643159249127 1.9162167146607998 0.5219193567333056 0.3288410521362218 0.15335640902825934 10.976794612879525 0.09560224977738742 0.18911368714831917 3.100344943756581e-06 5.508589983960571 0.8148523987358871 AGDNIPEEQPVASTPTTVS(ph)DGENKKDK ddPTM_PC-9_AZD4547_30min_R2 2 AGDNIPEEQPVASTPTTVSDGENKKDK 27 2 Q9Y320-2;Q9Y320 Q9Y320-2 TMX2 Thioredoxin-related transmembrane protein 2 1 AGDNIPEEQPVAS(0.03)T(0.03)PT(0.133)T(0.163)VS(0.645)DGENKKDK;AGDNIPEEQPVAS(0.027)T(0.027)PT(0.131)T(0.131)VS(0.683)DGENKKDK 63.63 0.00020195 16156800.0 57898.0 45492.0 61211.0 48357.0 47987.0 32314.0 67292.0 39180.0 47029.0 44344.0 True False 76308.35964678731 60196.39935545343 60399.30214544312 37209.040758202435 41324.83336591421 30293.40047170665 73280.85763812247 33125.631266832635 49514.85692839361 42791.530057263146 1.78325849869524 1.406736316156475 1.4114779739031873 0.8695421899709992 0.965724602756989 0.7079298270281142 1.712508469317616 0.7741165418133983 1.1571181694632882 1.0 15.38503764454874 -5.240649851131075 1.5380388957431201 1.035080736872322 1.748675648467172 0.42273658989731244 0.27554699139250843 0.526193781388345 1.9994297291315721 0.08060166582269003 0.43467809159434867 5.745795288556287e-06 5.240649851131075 0.7135949115948499 AGDNIPEEQPVASTPTTVS(ph)DGENKKDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGDNIPEEQPVASTPTTVSDGENKKDK 27 2 Q9Y320-2;Q9Y320 Q9Y320-2 TMX2 Thioredoxin-related transmembrane protein 2 1 AGDNIPEEQPVAS(0.002)T(0.002)PT(0.169)T(0.169)VS(0.659)DGENKKDK 84.68 2.996e-07 22109000.0 50686.0 41795.0 24565.0 35921.0 53702.0 30319.0 36985.0 33116.0 33086.0 30411.0 True False 59266.138705867656 45944.131386467685 25150.72276328129 33908.46282745329 43179.47860303259 28729.018266450916 33481.51305178812 32246.740089302344 33569.8201574376 35924.273566656455 1.6497519037065855 1.2789160872305372 0.7001038647758555 0.9438872233432114 1.2019582949371075 0.7997104858124702 0.9320025077101179 0.897630957783167 0.9344606536065305 1.0 15.132671363444912 -4.974108506963061 3.5896764680410427 0.9292728590142149 1.627707300111192 0.7708614700131915 0.12500043401855604 0.10546653398300032 2.800175258455707 0.03238359654744286 0.15331838334155334 1.0614303293975989e-05 4.974108506963061 0.698434441096977 AGDNIPEEQPVASTPTTVS(ph)DGENKKDK ddPTM_PC-9_Lapatinib_30min_R1 1 AGDNIPEEQPVASTPTTVSDGENKKDK 27 2 Q9Y320-2;Q9Y320 Q9Y320-2 TMX2 Thioredoxin-related transmembrane protein 2 1 AGDNIPEEQPVAS(0.019)T(0.019)PT(0.21)T(0.21)VS(0.541)DGENKKDK 58.361000000000004 0.00089318 7917300.0 166830.0 135790.0 55662.0 40244.0 47421.0 48232.0 49215.0 42148.0 71743.0 17571.0 True False 164450.97360712488 135475.58659791283 51085.68522153351 43203.67801004847 44631.79001327313 46169.22979428348 51763.11188915557 44106.34994883881 63662.54785271781 20608.1239381142 7.979909966621318 6.573892267182758 2.4789100344574226 2.0964391586438573 2.1657376550772662 2.2403412330461903 2.5117818606195885 2.140240910880065 3.089196670395385 1.0 14.330925554568667 -5.192296856688225 3.0120679097617993 2.2236651790406348 7.791688089176041 0.9439489298097447 0.49886837226320646 0.05085418326561157 0.8870173643214398 0.12560963516386095 0.4194211440069395 6.422485660835671e-06 5.192296856688225 5.568022910135406 AGDPGEMPQS(ph)PTGLGQPK ddPTM_PC-9_AZD4547_30min_R2 3 AGDPGEMPQSPTGLGQPK 18 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9;H0YHL2 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 AGDPGEMPQS(0.768)PT(0.232)GLGQPK;AGDPGEMPQS(0.812)PT(0.188)GLGQPK;AGDPGEMPQS(0.907)PT(0.093)GLGQPK 142.3 0.00014775 48883000.0 97358.0 97381.0 130062.0 164395.0 140192.0 119239.0 117408.0 137550.0 116869.0 123820.0 True False 128315.81882779938 128857.50386075367 128337.29289899886 126496.27262743116 120728.76069006688 111782.9664803441 127857.08455056627 116294.80808455408 123046.45674720786 119485.0994878746 1.0739064484004628 1.0784399428301115 1.0740861701506352 1.058678221549023 1.0104085045543145 0.9355389664439948 1.0700671891187676 0.973299671532313 1.02980586930586 1.0 16.866471191092288 -6.210485008902879 3.4164841163076103 1.0013076574534063 1.0743166213751594 0.5144234113076372 0.03273299811894352 0.19691257024224776 4.670083734754731 0.009849776247735548 0.012685572366228077 6.159067887894072e-07 6.210485008902879 0.07300896392175305 AGDPGEMPQS(ph)PTGLGQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGDPGEMPQSPTGLGQPK 18 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9;H0YHL2 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 AGDPGEMPQS(0.663)PT(0.337)GLGQPK;AGDPGEMPQS(0.79)PT(0.21)GLGQPK 152.89 2.5553e-05 41035000.0 115667.0 109779.0 123376.0 140355.0 156468.0 138433.0 157675.0 142968.0 134073.0 117180.0 True False 135247.13857261554 120677.13361586406 126317.75174608582 132491.36438704975 125809.21861493644 131173.3297826312 142738.88253185624 139215.24148711708 136033.5639838037 138423.8064036306 0.97705114522171 0.8717946482701182 0.9125435503323419 0.9571429064789447 0.9088698099233653 0.9476211729082373 1.031172933618393 1.0057174781134015 0.9827324325061748 1.0 17.07873255633411 -7.088501999043862 4.667435734712163 1.0048803805137456 0.9238052967688706 0.6309457249858147 0.028731722854939985 0.14364403960082384 5.372934185407855 0.011052055850067362 0.008574033829700527 8.156390327632929e-08 7.088501999043862 -0.08107508374487504 AGDPGEMPQS(ph)PTGLGQPK ddPTM_PC-9_Lapatinib_30min_R1 5 AGDPGEMPQSPTGLGQPK 18 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9;H0YHL2 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 AGDPGEMPQS(0.758)PT(0.242)GLGQPK;AGDPGEMPQS(0.8)PT(0.2)GLGQPK;AGDPGEMPQS(0.89)PT(0.11)GLGQPK;AGDPGEMPQS(0.999)PT(0.001)GLGQPK;AGDPGEMPQS(0.936)PT(0.064)GLGQPK 180.32 7.473499999999999e-09 76827000.0 383315.0 333102.0 403739.0 331650.0 410690.0 430969.0 406917.0 401706.0 457932.0 385255.0 True False 377848.85780863726 332330.72278472595 370545.13789760997 356040.6473519669 386534.0216476064 412537.46050780744 427985.1711998273 420370.7272598514 406354.8759222611 451845.81342997996 0.8362340572337523 0.7354958547961082 0.8200698709251873 0.7879693399154191 0.8554555783385729 0.9130049416109862 0.9471929549395942 0.9303410915081853 0.8993219895911057 1.0 18.785471029934058 -6.606602934714866 1.7686445209309167 0.9391073980055626 0.790245793634733 0.799127102714546 0.03407740640546254 0.1475795028499994 0.9451640196615401 0.01276614816914112 0.013087131450882535 2.4739850179537566e-07 6.606602934714866 -0.14886160437082963 AGDPGEMPQSPT(ph)GLGQPK ddPTM_PC-9_AZD4547_30min_R2 3 AGDPGEMPQSPTGLGQPK 18 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9;H0YHL2 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 AGDPGEMPQS(0.006)PT(0.994)GLGQPK;AGDPGEMPQS(0.083)PT(0.917)GLGQPK;AGDPGEMPQS(0.113)PT(0.887)GLGQPK 136.53 0.00033798 75506000.0 135763.3 121465.0 167376.0 205262.0 180360.0 167587.0 155329.0 182038.0 149800.0 173577.0 True False 178933.20534793395 160726.18587246453 165156.48487846451 157942.0171662873 155320.12724021688 157107.75839734782 169152.98008785554 153908.20991709217 157718.12217723878 167500.12206272653 1.0682571639018024 0.9595586193798399 0.9860081464096823 0.9429367287693089 0.9272836659907125 0.9379560830320655 1.009867801914258 0.9188543149804729 0.9416000432416132 1.0 17.353802621345885 AGDPGEMPQSPT(ph)GLGQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AGDPGEMPQSPTGLGQPK 18 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9;H0YHL2 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 AGDPGEMPQS(0.123)PT(0.877)GLGQPK;AGDPGEMPQS(0.007)PT(0.993)GLGQPK;AGDPGEMPQS(0.235)PT(0.765)GLGQPK;AGDPGEMPQS(0.119)PT(0.881)GLGQPK 106.26 0.0012349 61978000.0 109334.0 97848.0 119659.0 127859.0 160990.0 146431.0 167949.0 151571.0 136287.0 121466.0 True False 127842.08675506714 107561.70278509629 122512.12436928453 120695.47475447116 129445.16517638501 138751.90058295708 152039.6548745371 147592.42185274913 138279.93954532754 143486.82427567279 0.8909674278486481 0.7496277329160503 0.8538214221948992 0.8411606805276145 0.9021397318522406 0.9670009862116763 1.0596070798976795 1.0286130632397892 0.9637117571133809 1.0 17.13055874147817 -6.627664241797373 1.720673714844292 1.0157708694953238 0.8263212780113933 0.7998524182530621 0.04057840857784797 0.14599008400443483 0.888143979416076 0.01603360587965704 0.01619069434774234 2.3568707043529828e-07 6.627664241797373 -0.18944959148393048 AGDPGEMPQSPT(ph)GLGQPK ddPTM_PC-9_Lapatinib_30min_R1 2 AGDPGEMPQSPTGLGQPK 18 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9;H0YHL2 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 AGDPGEMPQS(0.025)PT(0.975)GLGQPK;AGDPGEMPQS(0.228)PT(0.772)GLGQPK 158.01 8.942899999999999e-18 12854000.0 126249.0 107308.0 131574.0 117638.0 132343.0 142200.0 131830.0 132515.0 147046.0 124743.0 True False 124448.66610876868 107059.53491898403 120756.49361032766 126289.49094886397 124558.84493634907 136118.43748439025 138655.51235085612 138672.13066979146 130484.13101697346 146304.6613404008 0.8506131313152031 0.7317575116071878 0.825376939490456 0.8631952652214655 0.8513662093550343 0.9303766280398222 0.9477176672331189 0.9478312543108174 0.8918658491227536 1.0 17.15861620963809 -6.366442666411865 0.9159597453304379 0.9484151301066687 0.7892649000091312 0.7084978133255204 0.03931710544642381 0.3102291393871778 0.5623966344814553 0.01963717081911983 0.028017941620282837 4.300880081514492e-07 6.366442666411865 -0.15915023009753748 AGDPT(ph)IQQISSR ddPTM_PC-9_AZD4547_30min_R2 1 AGDPTIQQISSR 12 0 K7EMC0 K7EMC0 CHD5 1 AGDPT(0.973)IQQIS(0.019)S(0.007)R 89.301 0.0185 8242900.0 25418.0 29335.0 35099.0 37283.0 34885.0 32145.0 35698.0 38256.0 29944.0 34953.0 True False 33500.395272756214 38816.96507280898 34633.56432672081 28687.980366607964 30041.81990893195 30134.968068422684 38875.05284381059 32344.41423542495 31526.778708112426 33729.30610886518 0.9932132954241593 1.1508379374162871 1.0268092742535833 0.8505357410559896 0.8906741162112423 0.8934357549828816 1.1525601125127485 0.9589409912860248 0.9346998899519651 1.0 15.041715018581556 -5.529519412644589 24.947503642386803 0.9544421368060372 1.0762251277928756 0.2433832006392106 0.0853105861099808 211.09547351995587 793036.0995960403 0.024279949610828033 0.042175723228875396 2.954476822582215e-06 5.529519412644589 0.12178299098683842 AGDPTIQQISS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 AGDPTIQQISSR 12 0 K7EMC0 K7EMC0 CHD5 1 AGDPT(0.128)IQQIS(0.18)S(0.693)R 65.232 0.042118 10973000.0 22275.0 32609.0 35698.0 43906.0 44582.0 37028.0 40223.0 46357.0 36075.0 35226.0 True False 29357.98665121743 43149.22154624947 35224.621195341155 33784.15004093793 38392.5588413359 34712.63330650353 43802.76907772408 39193.59082788569 37981.850851427844 33992.74846195992 0.8636543962919301 1.2693654823038578 1.036239280114692 0.9938634435148594 1.1294337933368246 1.0211776004329043 1.2885915690736867 1.152998583558074 1.1173515696717489 1.0 15.052939394330881 AGDRNS(ph)EDDGVVMTFSSVK ddPTM_PC-9_AZD4547_30min_R2 1 AGDRNSEDDGVVMTFSSVK 19 1 Q9NY61 Q9NY61 AATF Protein AATF 1 AGDRNS(1)EDDGVVMTFSSVK 76.76100000000001 0.005520000000000001 7951100.0 49980.0 59482.0 57111.0 41591.0 52601.0 74831.0 72245.0 83659.0 67783.0 56642.0 True False 65872.60035141862 78708.39326609253 56353.67082433547 32002.83752454447 45298.25910935155 70151.80574049281 78674.66504289042 70731.4238425715 71365.87099826292 54658.98082048299 1.205156030401749 1.4399901367461507 1.0310047860097935 0.5855000778307904 0.828743207966593 1.2834451848067394 1.439373070297128 1.2940494458701195 1.3056568184586268 1.0 15.738170938954235 -6.841918907134621 10.259999153189066 1.2946499635731945 1.0183635424337465 0.21306277897694337 0.23326171072123364 0.636806632058033 76.50675901695249 0.09233444788792676 0.08145913559921383 1.4390672604474023e-07 6.841918907134621 -0.276286421139448 AGDRNS(ph)EDDGVVMTFSSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGDRNSEDDGVVMTFSSVK 19 1 Q9NY61 Q9NY61 AATF Protein AATF 1 AGDRNS(1)EDDGVVMTFSSVK;AGDRNS(1)EDDGVVMTFSSVK 115.31 0.00011336 13374100.0 61630.0 105378.0 73783.0 60997.0 83522.0 50174.0 65137.0 51043.0 54335.0 47093.0 True False 72062.74175201483 115839.23142105971 75542.26654358553 57579.535844942206 67156.46366769375 47542.78711372101 58966.751808958295 49703.17533452896 55129.546583279094 55630.58811201714 1.29537982965253 2.0822938486252762 1.3579268008361596 1.035033743109109 1.2071859375721183 0.8546159357148873 1.0599699519664163 0.8934504743046612 0.9909934166482448 1.0 15.763590737015965 -5.579547178811279 3.5691299855461187 1.0062753777031324 1.6998727058243095 0.6534166266021113 0.1997570713215006 0.12026769991480557 3.118848015042983 0.05194879391141437 0.10022225308779964 2.6330118955582198e-06 5.579547178811279 0.6935973281211771 AGDRNS(ph)EDDGVVMTFSSVK ddPTM_PC-9_Lapatinib_30min_R1 2 AGDRNSEDDGVVMTFSSVK 19 1 Q9NY61 Q9NY61 AATF Protein AATF 1 AGDRNS(1)EDDGVVMTFSSVK;AGDRNS(1)EDDGVVMTFSSVK 131.94 6.2834e-05 21509400.0 126968.0 160793.0 110113.0 113789.0 136136.0 123982.0 135475.0 139104.0 129715.0 111957.0 True False 125157.41303692064 160420.69368759263 101059.9341884718 122157.42264897624 128128.74813367378 118679.57887615814 142489.23261573396 145567.27966411863 115105.13074049432 131308.61827667465 0.9531545962444515 1.2217072709544259 0.7696367193167233 0.9303077303850968 0.9757832335399288 0.9038217021375823 1.0851476048243927 1.1085889226052184 0.8765999692264017 1.0 17.002602083256953 -7.261177911923081 24.999229999278754 1.0266331979155583 0.961848579548436 0.0521854080204881 0.11935812509987351 77.92275465683952 7450782.942650864 0.04819742259918954 0.03495028182182353 5.480524052361528e-08 7.261177911923081 -0.06478461836712235 AGDSAVLVLPPS(ph)PGPR ddPTM_PC-9_AZD4547_30min_R2 6 AGDSAVLVLPPSPGPR 16 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;A0A087WVI1 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 AGDSAVLVLPPS(1)PGPR;AGDSAVLVLPPS(1)PGPR;AGDSAVLVLPPS(1)PGPR;AGDSAVLVLPPS(1)PGPR;AGDSAVLVLPPS(1)PGPR;AGDSAVLVLPPS(1)PGPR 196.45 7.2063e-12 269850900.0 313388.0 274643.0 429756.0 582886.0 487626.0 404211.0 346343.0 417997.0 341315.0 399316.0 True False 413038.86512465624 363415.97881341336 424057.1546424181 448510.63819892856 419927.54693744733 378935.62227112195 377166.8560447048 353405.16826549906 359356.2140916168 385336.0683823318 1.071892560845972 0.9431143581732679 1.1004865348386415 1.163946681871251 1.089769635892983 0.9833899636281664 0.9787997724378049 0.9171349304235107 0.9325787113576461 1.0 18.555757706478694 -6.891525497711575 3.7828072144871276 0.9533137858854398 1.0729177557009764 0.5036197049126491 0.055608258123325066 0.21520889022312625 5.838041400518274 0.022698541712041633 0.019840366920734112 1.2837323994956157e-07 6.891525497711575 0.11960396981553656 AGDSAVLVLPPS(ph)PGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 AGDSAVLVLPPSPGPR 16 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;A0A087WVI1 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 AGDSAVLVLPPS(1)PGPR;AGDSAVLVLPPS(1)PGPR;AGDSAVLVLPPS(1)PGPR;AGDSAVLVLPPS(1)PGPR;AGDSAVLVLPPS(1)PGPR;AGDSAVLVLPPS(1)PGPR;AGDSAVLVLPPS(1)PGPR 141.1 3.5042000000000003e-06 194200100.0 199719.1 201218.6 252201.8 288388.0 326672.0 316932.0 330826.0 318881.0 302509.0 241181.3 True False 233527.5989979687 221194.2528006001 258215.24739265244 272230.55532651057 262662.9666345735 300311.5279931005 299487.7663071748 310510.71163234796 306932.6218341988 284905.5604998802 0.8196666944240525 0.7763774508735611 0.9063187357228187 0.9555115556497714 0.9219299411837346 1.0540739445947978 1.0511825946173514 1.0898724162755629 1.077313553640972 1.0 18.12012425344262 -5.895997002958722 0.7052035441130593 1.0685138272921837 0.7663050756033243 0.8540000569065626 0.0395029316296379 0.335052607909946 0.30810025122326445 0.02160115363317327 0.06511754184609768 1.2705828733977277e-06 5.895997002958722 -0.3022087516888594 AGDSAVLVLPPS(ph)PGPR ddPTM_PC-9_Lapatinib_30min_R1 5 AGDSAVLVLPPSPGPR 16 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;A0A087WVI1 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 AGDSAVLVLPPS(1)PGPR;AGDSAVLVLPPS(1)PGPR;AGDSAVLVLPPS(1)PGPR;AGDSAVLVLPPS(1)PGPR;AGDSAVLVLPPS(1)PGPR 199.61 3.7236e-12 226280600.0 285388.0 261859.0 299382.0 280982.0 355249.0 351973.0 309402.0 317375.0 389790.0 292507.0 True False 281318.31478625076 261252.6815740686 274767.9676079404 301646.35360847384 334353.9522664067 336919.93527913716 325421.3216443874 332121.40113440005 345887.74552933197 343066.44520892156 0.8200111631871568 0.7615221051856885 0.8009176398484888 0.8792651039502754 0.9746040655849944 0.9820836166998458 0.9485664546592757 0.9680964308011639 1.008223772274471 1.0 18.388128499492886 -6.011407617990133 2.1631119186284145 0.9785125239634986 0.7878312518839529 0.9430348249835049 0.020639428189335233 0.06673562002565343 0.6254101306332114 0.006646005536732159 0.010290462390680797 9.740749660243316e-07 6.011407617990133 -0.19068127207954577 AGDT(ph)SDQEGHSLEEK ddPTM_PC-9_AZD4547_30min_R2 1 AGDTSDQEGHSLEEK 15 0 A0A087WU18;Q99607 A0A087WU18 ELF4 ETS-related transcription factor Elf-4 1 AGDT(0.5)S(0.5)DQEGHSLEEK 80.596 0.020309999999999998 9518400.0 34925.0 32582.0 40347.0 55896.0 52877.0 47560.0 38995.0 48774.0 38476.0 41502.0 True False 46030.42351487178 43113.49432426327 39811.972417738536 43010.040784591336 45535.9412734583 44586.06568157359 42465.47945667529 41237.099015020314 40509.76280968917 40049.02761222565 1.1493518384656163 1.0765178805765099 0.9940808751517666 1.073934708253985 1.1370049159335314 1.113287096837351 1.0603373412170432 1.0296654244467096 1.0115042792530342 1.0 15.28947959406732 -7.753979624371387 2.347440587368395 1.0090198340771221 1.0869010542828885 0.42381064930547685 0.04033005525620685 0.35030288357681383 3.8426207219799284 0.029378807336832437 0.012748608721309134 1.7620587143092002e-08 7.753979624371387 0.07788122020576638 AGDT(ph)SDQEGHSLEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGDTSDQEGHSLEEK 15 0 A0A087WU18;Q99607 A0A087WU18 ELF4 ETS-related transcription factor Elf-4 1 AGDT(0.495)S(0.495)DQEGHS(0.01)LEEK 88.781 0.046112 0.0 40811.0 46656.0 52978.0 50389.0 56857.0 58772.0 45662.0 48745.0 52737.0 36836.0 True False 47719.49624600805 51287.69934123785 54241.19644018385 47565.86769334217 45716.27900138957 55689.89285780707 41336.56479574827 47465.49539959666 53508.17885639805 43514.075206384434 1.0966450744886012 1.1786461989134234 1.2465207219255234 1.0931145259951025 1.0506089991470628 1.2798133154312374 0.9499584812429456 1.090807863305629 1.2296751936611827 1.0 15.409194514900149 -14.52287873932825 0.14484264373707126 0.5586556256635453 1.1754837188661067 0.13712930682856794 0.09619498220750361 277.5223900618788 2.4177840936773287 35.701195575307835 0.5367191256284114 3.0000000411155608e-15 14.52287873932825 0.6168280932025614 AGDT(ph)SDQEGHSLEEK ddPTM_PC-9_Lapatinib_30min_R1 1 AGDTSDQEGHSLEEK 15 0 A0A087WU18;Q99607 A0A087WU18 ELF4 ETS-related transcription factor Elf-4 1 AGDT(0.5)S(0.5)DQEGHSLEEK 77.03699999999999 0.027961 19954000.0 48882.0 36957.0 51834.0 41569.0 45259.0 40089.0 40091.0 38273.0 46696.0 31612.0 True False 48184.93371613909 36871.42833713133 47572.40860502624 44626.12293011892 42596.95460261758 38374.48692202335 42166.715813230454 40051.30330245581 41436.6047493206 37076.09207965773 1.2996227761171293 0.9944798998209768 1.2831020190266345 1.2036361015136117 1.1489062685219984 1.035019732920504 1.1373020576881607 1.0802460846306525 1.117609824150138 1.0 15.178201567568598 -6.563159525723852 5.913533438560285 1.083255297700378 1.1860607269344943 0.30715519230659705 0.08527703958115852 0.26326112633433474 23.592558452026573 0.027040457754634647 0.02732244867863849 2.734264187654049e-07 6.563159525723852 0.10280542923411629 AGDTETLK ddPTM_PC-9_Lapatinib_30min_R1 1 AGDTETLK 8 0 C9JNG9;P12111 C9JNG9 COL6A3 Collagen alpha-3(VI) chain 0 97.071 0.027302 54672000.0 102870.0 86982.0 128780.0 79614.0 68491.0 90003.0 95870.0 114730.0 103260.0 49371.0 False True 101403.05493595231 86780.59852315835 118192.20550517582 85469.07914451849 64462.49403848698 86153.78149724047 100833.67950448729 120060.7746424571 91629.77142399436 57904.711567277685 1.7512055960789177 1.4986794023199765 2.041150060264992 1.4760297880978928 1.1132512759966002 1.4878544278239099 1.741372623665205 2.073419785589679 1.5824234150192178 1.0 15.821393121169775 -11.413139751595004 2.2963164531551414 0.642286836076046 1.6390563845007116 0.3383404192359214 0.26874163035229126 15577322.562173711 7635929.116800867 30153277.361530412 0.07198196458959774 3.862426680497111e-12 11.413139751595004 0.9967695484246656 AGDTS(ph)DQEGHSLEEK ddPTM_PC-9_AZD4547_30min_R2 2 AGDTSDQEGHSLEEK 15 0 A0A087WU18;Q99607 A0A087WU18 ELF4 ETS-related transcription factor Elf-4 1 AGDT(0.182)S(0.817)DQEGHS(0.001)LEEK;AGDT(0.073)S(0.927)DQEGHSLEEK 95.751 0.0027776999999999997 5999200.0 64488.0 51230.0 77125.0 82407.0 86733.0 69514.0 61399.0 79609.0 63226.0 79718.0 True False 84993.84256627216 67789.09564274775 76102.2721074202 63409.33932545826 74691.6200705575 65167.27859101991 66863.39205437638 67307.25828283007 66567.99728156278 76927.09708427083 1.1048622109471322 0.8812121893601063 0.9892778356637185 0.8242783327179971 0.9709403175416271 0.8471303488760472 0.8691786716081327 0.8749486310278602 0.8653387402444157 1.0 16.23120424747895 -2.6073069319314417 1.5553212664348866 0.8949529776194791 199.99990428407682 0.48715297851598893 0.06054270131503445 1031.0334446877396 3.5560357401037397 0.015992018037307137 731397.3464999505 0.0024699779035205127 2.6073069319314417 199.10495130645734 AGDTS(ph)DQEGHSLEEK ddPTM_PC-9_Lapatinib_30min_R1 2 AGDTSDQEGHSLEEK 15 0 A0A087WU18;Q99607 A0A087WU18 ELF4 ETS-related transcription factor Elf-4 1 AGDT(0.238)S(0.762)DQEGHSLEEK;AGDT(0.069)S(0.931)DQEGHSLEEK 105.52 0.00058862 19718500.0 91435.0 73966.0 91696.0 76770.0 89462.0 84342.0 77663.0 87065.0 83496.0 60928.0 True False 90131.12013287465 73794.73627145754 84157.1088367958 82415.92189721245 84200.02104905935 80734.88927080491 81684.01013202251 91110.35774640892 74091.80122814103 71459.32361854312 1.2612926567008025 1.032681706664075 1.177692490990185 1.1533263642006568 1.178293003422861 1.129802035375757 1.1430840091358794 1.2749960835448841 1.036838826290189 1.0 16.124834638045936 -8.456221198489512 8.024723612255407 1.0000847365847263 1.162157432167708 0.46926330580775566 0.06428271690954632 0.22681789786160447 24.125515068159952 0.05840236803234471 0.015096174010435002 3.497669754186247e-09 8.456221198489512 0.16207269558298165 AGEAPTENPAPPTQQSS(ph)AE ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGEAPTENPAPPTQQSSAE 19 0 P16989-2;P16989 P16989-2 YBX3 Y-box-binding protein 3 1 AGEAPTENPAPPT(0.003)QQS(0.168)S(0.829)AE 127.49 5.9136000000000004e-06 0.0 9512.2 7394.7 6864.5 7799.6 10415.0 10906.0 8693.6 11035.0 9167.5 7421.7 True False 11122.427585486223 8128.796946130226 7028.175713761221 7362.613698644374 8374.255514703078 10334.070161084253 7870.079271786542 10745.342942548961 9301.557344293935 8767.19545985512 1.268641452835822 0.9271832689657584 0.8016446930997662 0.8397912117230295 0.9551806564651936 1.178720174359501 0.8976735271642498 1.2256305898222246 1.0609501506936456 1.0 13.097899697087705 -6.622408333824515 9.230889588740977 1.075550089504075 0.9397975746411855 0.12959350620590337 0.14426502876878033 0.540053941394422 45.46197015477756 0.04835031582916409 0.048325462548205314 2.385567262030179e-07 6.622408333824515 -0.13575251486288953 AGEAPTENPAPPTQQSS(ph)AE ddPTM_PC-9_Lapatinib_30min_R1 1 AGEAPTENPAPPTQQSSAE 19 0 P16989-2;P16989 P16989-2 YBX3 Y-box-binding protein 3 1 AGEAPTENPAPPT(0.003)QQS(0.229)S(0.767)AE 115.2 0.00074857 0.0 18241.0 21863.0 20891.0 18403.0 20014.0 18568.0 19635.0 16223.0 18242.0 13997.0 True False 17980.879995010284 21812.37756675873 19173.422621592068 19756.418010608344 18836.815869037942 17773.889924122068 20651.604225207135 16976.77980497323 16187.393863223964 16416.362800169845 1.0953023037980283 1.328697338885143 1.1679458388549806 1.2034589056720861 1.147441494704482 1.0826935381775418 1.2579890245233536 1.0341377083112215 0.9860523954219925 1.0 14.002846899392518 -7.884623084798095 5.855991854009915 0.9989143687462457 1.183476112212141 0.5858962717424517 0.06848249197936711 0.14430458375925218 6.751276040372503 0.03781973918282422 0.0178340176266144 1.3042982608807259e-08 7.884623084798095 0.18456174346589538 AGEARPGPTAES(ph)ASGPSEDPSVNFLK ddPTM_PC-9_AZD4547_30min_R2 1 AGEARPGPTAESASGPSEDPSVNFLK 26 1 Q13501;Q13501-2;E7EMC7;E9PFW8 Q13501 SQSTM1 Sequestosome-1 1 AGEARPGPT(0.015)AES(0.785)AS(0.187)GPS(0.013)EDPSVNFLK 80.453 1.5372e-05 6032100.0 16278.0 13016.0 20234.0 38943.0 32299.0 17372.0 12156.0 27382.0 16201.0 23694.0 True False 21454.065396566446 17223.167458247208 19965.68393933925 29965.293013352293 27814.84137132271 16285.726093782523 13237.860450707652 23150.741075763435 17057.351785002986 22864.480271892324 0.9383141510957621 0.7532717671006905 0.8732183588657114 1.3105608637074122 1.2165087962010641 0.7122718688604014 0.5789705382886472 1.012519891135379 0.7460196594090908 1.0 14.48082050544327 -6.783450979356709 24.9646424963106 0.7963022560469601 1.0118152542377428 0.22615019820678894 0.19174727091393148 395.01537204644586 448006.81318459596 0.07379019360175415 0.06512778124980094 1.646451797773926e-07 6.783450979356709 0.21551299819078262 AGEARPGPTAES(ph)ASGPSEDPSVNFLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGEARPGPTAESASGPSEDPSVNFLK 26 1 Q13501;Q13501-2;E7EMC7;E9PFW8 Q13501 SQSTM1 Sequestosome-1 1 AGEARPGPT(0.023)AES(0.767)AS(0.148)GPS(0.043)EDPS(0.018)VNFLK;AGEARPGPT(0.038)AES(0.76)AS(0.18)GPS(0.02)EDPS(0.003)VNFLK 65.197 0.00023472 12135300.0 17224.5 10624.0 22540.0 24761.0 27447.0 26857.0 22480.0 27503.0 28684.0 17158.4 True False 20140.267650617887 11678.680508430029 23077.439083426016 23373.721446245105 22068.957379938078 25448.57164095359 20350.531658894066 26781.075391837254 29103.449235203403 20269.082094180336 0.9936447815957372 0.5761820122966108 1.1385537330302695 1.153171186422703 1.0887990525369928 1.255536463008376 1.0040184140719977 1.3212771682209843 1.4358543272938638 1.0 14.306993135933997 -5.374658335164482 6.60888735239277 1.181948562995222 0.7873687452077116 0.4925108220835027 0.15852602839390315 0.17746430529852017 9.044247935886109 0.040659927886521806 0.08559102380679043 4.220283878104149e-06 5.374658335164482 -0.3945798177875104 AGEARPGPTAESASGPS(ph)EDPSVNFLK ddPTM_PC-9_Lapatinib_30min_R1 2 AGEARPGPTAESASGPSEDPSVNFLK 26 1 Q13501;Q13501-2;E7EMC7;E9PFW8 Q13501 SQSTM1 Sequestosome-1 1 AGEARPGPT(0.023)AES(0.243)AS(0.311)GPS(0.401)EDPS(0.022)VNFLK;AGEARPGPTAES(0.007)AS(0.094)GPS(0.898)EDPSVNFLK 102.03 8.6934e-10 12936300.0 52719.0 30276.0 37843.0 28097.7 25569.2 26351.0 16943.7 17988.8 34015.0 19909.0 True False 51967.21739251943 30205.897782151882 34731.6946182044 30164.09858917949 24065.26992698135 25224.02915718121 17820.96187983918 18824.625319343053 30183.872506170574 23350.24412292501 2.225553493956776 1.29360094152061 1.4874231907539333 1.291810844905245 1.030621769960612 1.0802469140961373 0.7632023796420507 0.806185375203904 1.2926576847449909 1.0 14.511150012700327 -1.5228787452876833 0.521642321259794 0.9645655090327587 43.51124180797745 0.7737241916083866 0.18918252585374276 55.15309155325093 0.5509518879884812 0.10017753242124525 2598.065150177321 0.029999999999492575 1.5228787452876833 42.54667629894469 up AGEIS(ph)GEVSTGSPQK ddPTM_PC-9_AZD4547_30min_R2 1 AGEISGEVSTGSPQK 15 0 C9K0U2 C9K0U2 FBXO24 1 AGEIS(0.823)GEVS(0.031)T(0.095)GS(0.051)PQK 93.228 0.0033427 24952000.0 36091.0 38355.0 42705.0 52499.0 54561.0 46620.0 36236.0 47096.0 37807.0 43202.0 True False 47567.18726056515 50752.50367709524 42138.70379704869 40396.16665146451 46986.146941414205 43704.84403017159 39460.93380156648 39818.39535841625 39805.400835479755 41689.511129665385 1.1409869286454006 1.2173926319078572 1.0107747165944498 0.9689767415554903 1.1270496023634071 1.0483414855654696 0.9465434525924893 0.9551178289083442 0.9548061312514424 1.0 15.347396834090986 -3.9243522654255245 0.3763130950697078 0.9646451571624612 1.5451626685637079 0.5218651043088014 0.06181597638189725 9.437333020911229 0.6441353017544641 0.05497810853386868 2.811983110324127 0.00011902761582420364 3.9243522654255245 0.5805175114012466 AGEIS(ph)GEVSTGSPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGEISGEVSTGSPQK 15 0 C9K0U2 C9K0U2 FBXO24 1 AGEIS(0.864)GEVS(0.042)T(0.042)GS(0.053)PQK 67.095 0.030529 23639000.0 31119.0 31223.0 21956.0 34130.0 35012.0 31077.0 35271.0 31739.0 27144.0 22415.0 True False 36386.832071733734 34322.61309438164 22479.514308593694 32217.80675095295 28151.649935744994 29447.26741206816 31929.8755400735 30905.884880250258 27540.92964859715 26478.662062957635 1.374194511233902 1.2962366834386738 0.8489671515556462 1.2167460226785438 1.0631824927109057 1.1121131174245944 1.2058719380969722 1.1671996419896946 1.0401178723877282 1.0 14.692542605776849 -5.0219226585366386 24.409818413947924 1.095763706117382 1.3547051937053547 0.49315559629052796 0.1033189210085801 389.14140042824425 433293.556158066 0.02531406563467872 0.0684257553493106 9.507740974715307e-06 5.0219226585366386 0.25894148758797275 AGEIS(ph)GEVSTGSPQK ddPTM_PC-9_Lapatinib_30min_R1 1 AGEISGEVSTGSPQK 15 0 C9K0U2 C9K0U2 FBXO24 1 AGEIS(0.854)GEVS(0.067)T(0.067)GS(0.013)PQK 76.868 0.013506 24238000.0 19404.0 18308.0 19526.0 18885.0 17098.0 16864.0 14489.0 15784.0 17723.0 13428.0 True False 19127.295401742205 18265.608950840167 17920.64765253969 20273.865898513202 16092.329255961371 16142.766031904057 15239.169524778514 16517.382262324936 15726.84910853625 15749.011908314682 1.2145076474063723 1.1597939640389026 1.1378902852361483 1.2873103415338474 1.0217992944348104 1.0250018303295265 0.9676270240632051 1.0487884800953509 0.998592749824087 1.0 13.942973696435542 -6.336297728285935 8.168018587489176 1.01076642038076 1.1923873759089887 0.831806026841306 0.04171360116898622 0.13089598929040056 13.138670062785849 0.012715608260014992 0.014427245889816535 4.6100142911444697e-07 6.336297728285935 0.18162095552822866 AGELIS(ph)ET(ph)KY(ph)RK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGELISETKYRK 12 2 A0A0A0MRM2;Q86VF7-4;Q86VF7-3;Q86VF7;Q86VF7-2 A0A0A0MRM2 NRAP Nebulin-related-anchoring protein 3 AGELIS(1)ET(1)KY(1)RK 68.83 0.024174 0.0 17644.0 21490.0 17439.0 18987.0 31210.0 17655.0 24479.0 18068.0 19576.0 18316.0 True False 20630.780715115205 23623.385177537763 17854.81189777579 17923.21994668454 25094.624542859616 16729.140720148775 22160.17190738735 17593.734144628426 19862.261965846516 21636.545810623764 0.9535154500024344 1.0918279370609352 0.8252154504721774 0.828377140397524 1.159825822592158 0.7731890693908543 1.0242010023848853 0.81314893322712 0.9179959749441126 1.0 14.401182576512344 AGELTEDEVER ddPTM_PC-9_AZD4547_30min_R2 1 AGELTEDEVER 11 0 P62269 P62269 RPS18 40S ribosomal protein S18 0 134.84 0.00030253 15816000.0 20329.0 27536.0 31967.0 44592.0 39588.0 33384.0 25968.0 30390.0 29968.0 31855.0 False True 26793.199130531943 36436.47350417144 31543.096693133248 34312.00333953229 34091.88953862112 31296.49320255788 28279.101693318218 25693.923792727004 31552.047299115417 30739.766145907368 0.871613629178475 1.185320452056286 1.0261332680090292 1.116208990552146 1.1090484350727583 1.018110972412997 0.9199517510670211 0.8358529362510405 1.0264244415312898 1.0 14.907818569255328 -7.085785764602612 3.8495661359471587 0.9327959599318254 1.069421243140895 0.2619474272804787 0.09014541118257165 0.27323753181867133 7.500118049672165 0.03403331971913029 0.026376110666087475 8.207563196642056e-08 7.085785764602612 0.13662528320906953 AGELTEDEVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGELTEDEVER 11 0 P62269 P62269 RPS18 40S ribosomal protein S18 0 ; 133.75 0.00025261 20875900.0 77944.0 75405.0 77823.0 72017.0 92247.0 72390.0 66122.0 71999.0 71078.0 54848.0 False True 91138.37973582759 82890.71006571606 79678.59546537117 67982.12097226431 74171.86255063025 68593.74096468813 59858.4454781758 70109.1025392463 72117.38128363508 64791.508223470904 1.4066408119638811 1.2793452774678375 1.2297691109543794 1.049244304327486 1.1447775269377243 1.058684121507143 0.9238625109901658 1.082072395929334 1.1130684137633697 1.0 15.983517120951298 -5.03077882803164 0.7469713028310004 1.0367872083094436 1.5483276412665445 0.8081008715098115 0.05919112409535487 0.9071994031198436 0.48798587769958585 0.025881016860228305 0.36678139851879205 9.315821790038574e-06 5.03077882803164 0.5115404329571009 AGELTEDEVER ddPTM_PC-9_Lapatinib_30min_R1 2 AGELTEDEVER 11 0 P62269 P62269 RPS18 40S ribosomal protein S18 0 ; 161.51 0.0015937000000000002 40125000.0 97891.0 103915.0 90966.0 86524.0 88380.0 82270.0 79734.0 82322.0 88185.0 74629.0 False True 96495.05638898897 103674.3912020188 83487.12661891467 92887.2635956029 83181.66216176543 78751.50388073694 83862.23637854168 86146.98065123626 78252.67667078198 87528.52321310813 1.1024412711048464 1.1844640740664603 0.9538276615914819 1.0612227898492894 0.9503377768552169 0.8997238955922798 0.9581132332640866 0.9842160873832158 0.8940248709584419 1.0 16.417465608979903 -5.427041561083648 1.1458886516587936 0.9483758358966506 1.1617605212096616 0.6018892460184633 0.05505784602152557 0.4418439560974498 0.9412021493597674 0.017953369862376674 0.08700055587917895 3.7407478837556023e-06 5.427041561083648 0.2133846853130109 AGEPDGES(ph)LDEQPSSSSSK ddPTM_PC-9_AZD4547_30min_R2 4 AGEPDGESLDEQPSSSSSK 19 0 Q9H3Q1;J3KRZ9 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 AGEPDGES(1)LDEQPSSSSSK;AGEPDGES(1)LDEQPSSSSSK;AGEPDGES(1)LDEQPSSSSSK;AGEPDGES(1)LDEQPSSSSSK 193.06 9.269199999999998e-48 37875900.0 100572.0 122982.0 143236.0 166219.0 163444.0 182948.0 154785.0 194670.0 163157.0 158662.0 True False 132551.80397244627 162733.5264559127 141336.59705126018 127899.77760795034 140752.62184880255 171508.23263903524 168560.56514172288 164588.2245715749 171781.14592838276 153107.29167295445 0.8657445541887331 1.0628724777100782 0.9231212668379171 0.8353604600436095 0.9193071101372353 1.1201833091358326 1.1009310092283355 1.0749861928401447 1.1219658061440776 1.0 17.22418346667954 -6.75599248119964 24.98885617042871 1.0893822668156201 0.9244761847097139 0.616108198851391 0.06396351912174512 91.91642492587235 421686.53498893726 0.021880970598464652 0.021282943638271948 1.7539108664723297e-07 6.75599248119964 -0.16490608210590618 AGEPDGES(ph)LDEQPSSSSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGEPDGESLDEQPSSSSSK 19 0 Q9H3Q1;J3KRZ9 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 AGEPDGES(1)LDEQPSSSSSK;AGEPDGES(1)LDEQPSSSSSK 252.83 1.0427999999999999e-86 10347000.0 47672.0 53114.0 57351.0 55373.0 69326.0 45820.0 51928.0 41077.0 39844.0 39023.0 True False 55741.92803508116 58386.806901802745 58718.46534487872 52270.63033168816 55742.06796085508 43417.118538499955 47009.00391383679 39998.77227467909 40426.64312255767 46097.56099410197 1.2092164277891655 1.2665921068855062 1.2737868138488184 1.1339131443066155 1.2092194632160058 0.9418528356425415 1.0197720421662098 0.867698234181995 0.8769800885502407 1.0 15.492402799731181 -6.7412625812994404 1.308569209670765 0.9157368220135822 1.2419605656418335 0.8272405822557298 0.062217829473074235 0.15893803987860125 0.5711892492100542 0.02857496061508306 0.02625892959108741 1.8144183051173827e-07 6.7412625812994404 0.32622374362825135 AGEPDGES(ph)LDEQPSSSSSK ddPTM_PC-9_Lapatinib_30min_R1 4 AGEPDGESLDEQPSSSSSK 19 0 Q9H3Q1;J3KRZ9 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 AGEPDGES(1)LDEQPSSSSSK;AGEPDGES(1)LDEQPSSSSSK;AGEPDGES(0.985)LDEQPS(0.01)S(0.003)S(0.001)SSK;AGEPDGES(1)LDEQPSSSSSK 261.66 2.3806999999999996e-66 52076800.0 72259.0 131740.0 140896.0 135739.0 163195.0 150004.0 147875.0 160204.0 148513.0 118057.0 True False 71228.57340932218 131434.96412408166 129312.07475428838 145721.6988720302 153596.1909537149 143588.67859640284 155531.2439420681 167647.66269345605 131785.90202877883 138462.99514893547 0.5144231737346597 0.9492425321487937 0.9339107146656472 1.0524234198118205 1.1092941532031835 1.0370184354451817 1.1232693888700982 1.2107759370157245 0.951777057018198 1.0 17.079140935560353 -4.508339929753773 1.2280870804276915 1.0756967172838265 2.8756977519323394e-18 0.8106036386977363 0.0777713861474861 1.0492871591824278 0.8814089430918404 0.022744239572735164 1.6835930384460405 3.1021305467411274e-05 4.508339929753773 -1.0756967172838265 AGEPDGES(ph)LDEQPSSSSSKR ddPTM_PC-9_AZD4547_30min_R2 2 AGEPDGESLDEQPSSSSSKR 20 1 Q9H3Q1;J3KRZ9 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 AGEPDGES(0.999)LDEQPSSSSSKR;AGEPDGES(1)LDEQPSSSSSKR 80.314 0.00066673 43120000.0 45682.0 38399.0 58015.0 107050.0 99993.0 60014.0 47205.0 69558.0 47386.0 63848.0 True False 60207.92575537218 50810.72581662835 57245.683193672376 82371.27640601303 86110.6979548183 56261.315092808174 51406.15355179781 58809.40938382705 49890.72721956368 61612.700953818734 0.9771999088386096 0.8246794091158751 0.9291214685845437 1.336920393536289 1.397612774991991 0.9131447610936316 0.8343434512038167 0.9545014010651331 0.8097474456923881 1.0 15.91094016089704 -6.962535655067691 24.99904067328989 0.8926968361902117 1.0899040866116283 0.23845651194273687 0.17035803370099753 279.829397387978 186722.56304666493 0.06812714532995598 0.06008235916713766 1.0900949931906428e-07 6.962535655067691 0.19720725042141662 AGEPDGES(ph)LDEQPSSSSSKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGEPDGESLDEQPSSSSSKR 20 1 Q9H3Q1;J3KRZ9 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 AGEPDGES(1)LDEQPSSSSSKR 97.689 0.00019961 11403000.0 14393.0 8113.0 14838.0 20695.0 19868.0 20872.0 18981.0 19762.0 18022.0 17653.0 True False 16829.450625292062 8918.4050230509 15191.794193428355 19535.526244095257 15975.008023631353 19777.435576943935 17182.98226946034 19243.268439569787 18285.537655725697 20853.3491589289 0.80703826023486 0.4276725505855856 0.728506201936565 0.9368052150860677 0.7660643814037535 0.948405717768156 0.8239914911750759 0.9227903054282427 0.8768633525659005 1.0 14.347991486334472 -5.5621630818071655 5.088141570389147 0.8852353007475643 0.6073228485847062 0.5367463846949656 0.10578671761115975 0.1222763712758148 7.579790021399492 0.026557532268358996 0.04839378853275802 2.7405448773957066e-06 5.5621630818071655 -0.2779124521628581 AGEPDGES(ph)LDEQPSSSSSKR ddPTM_PC-9_Lapatinib_30min_R1 1 AGEPDGESLDEQPSSSSSKR 20 1 Q9H3Q1;J3KRZ9 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 AGEPDGES(1)LDEQPSSSSSKR 75.868 0.0010333 27430000.0 25197.0 15584.0 25387.0 21775.0 17600.0 20312.0 16550.0 18545.0 23260.0 15047.0 True False 24837.686159436118 15547.9162054781 23299.77885665393 23376.406139270606 16564.802602931333 19443.30310958464 17406.878020228076 19406.668401850988 20640.2138613414 17647.8539011328 1.4074054725624066 0.8810088916522646 1.3202613182987841 1.3246033353534334 0.9386298580966864 1.1017375380887868 0.9863453152856588 1.0996616648444315 1.169559425014082 1.0 14.10720513219929 -6.260376631729552 24.991462936969253 1.0537772982873923 1.2143648012298447 0.27484900017761627 0.14500570845777022 150.58659471873773 3541167.196985956 0.0431121621515484 0.05250351668762396 5.490645039808937e-07 6.260376631729552 0.1605875029424524 AGEPNS(ph)PDAEEANS(ph)PDVTAGCDPAGVHPPR ddPTM_PC-9_AZD4547_30min_R2 3 AGEPNSPDAEEANSPDVTAGCDPAGVHPPR 30 0 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 2 AGEPNS(1)PDAEEANS(0.999)PDVT(0.001)AGCDPAGVHPPR;AGEPNS(1)PDAEEANS(0.995)PDVT(0.005)AGCDPAGVHPPR;AGEPNS(0.775)PDAEEANS(0.999)PDVT(0.226)AGCDPAGVHPPR 100.73 2.9532e-12 77400300.0 25058.6 25800.0 33595.5 47491.0 39357.0 37929.7 33738.3 41498.6 31569.699999999997 34276.7 True False 33026.713548740634 34139.3454535017 33150.001719090265 36542.68367863579 33892.95990127086 35557.949862960064 36740.94334025253 35085.94491296021 33238.409891180076 33076.683166015486 0.9984892796830913 1.032127232411805 1.002216623495977 1.104786822040894 1.0246783128513337 1.0750155837721342 1.1107807622622172 1.060745563176937 1.004889448085011 1.0 15.013526952031585 -5.726501790080526 24.999833091761364 1.0589129544780962 1.0130626270450083 0.22265419144250975 0.036485759660524635 258.95084214411105 185292.1443287269 0.009761297777764114 0.016906166217617213 1.877146681111982e-06 5.726501790080526 -0.04585032743308792 AGEPNS(ph)PDAEEANS(ph)PDVTAGCDPAGVHPPR ddPTM_PC-9_Lapatinib_30min_R1 6 AGEPNSPDAEEANSPDVTAGCDPAGVHPPR 30 0 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 2 AGEPNS(1)PDAEEANS(1)PDVTAGCDPAGVHPPR;AGEPNS(1)PDAEEANS(0.995)PDVT(0.006)AGCDPAGVHPPR;AGEPNS(1)PDAEEANS(0.993)PDVT(0.007)AGCDPAGVHPPR;AGEPNS(1)PDAEEANS(0.86)PDVT(0.141)AGCDPAGVHPPR;AGEPNS(1)PDAEEANS(0.999)PDVT(0.001)AGCDPAGVHPPR;AGEPNS(1)PDAEEANS(0.998)PDVT(0.002)AGCDPAGVHPPR 164.8 2.6997e-32 92614000.0 39506.6 56468.9 62494.299999999996 58953.6 64342.7 60905.7 56658.5 54413.0 70867.6 50107.7 True False 38943.22863937686 56338.14973148887 57356.25988897423 63289.24440744448 60558.18888861534 58300.9051891212 59591.99989783038 56941.22662442266 62885.74461908848 58768.7491806866 0.662651990765441 0.9586412934921454 0.9759652993911845 1.07692005172442 1.030448830932696 0.9920392385734296 1.0140083076230304 0.9689031571755057 1.0700541613663417 1.0 15.84276157224357 -4.597503411947864 1.9762373131982707 1.0173279182102504 0.4069199334232401 0.9052503942710127 0.03411069597598554 0.39463775846263976 1.0820327947454893 0.009081495529026876 0.5200024073678159 2.5263678621493637e-05 4.597503411947864 -0.6104079847870103 AGEPNS(ph)PDAEEANSPDVTAGCDPAGVHPPR ddPTM_PC-9_AZD4547_30min_R2 5 AGEPNSPDAEEANSPDVTAGCDPAGVHPPR 30 0 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 AGEPNS(0.999)PDAEEANS(0.001)PDVTAGCDPAGVHPPR;AGEPNS(1)PDAEEANSPDVTAGCDPAGVHPPR;AGEPNS(1)PDAEEANSPDVTAGCDPAGVHPPR;AGEPNS(1)PDAEEANSPDVTAGCDPAGVHPPR;AGEPNS(0.894)PDAEEANS(0.106)PDVTAGCDPAGVHPPR 145.46 3.2814999999999997e-17 1022997800.0 354733.1 425426.9 622206.0 914104.0 828030.0 647027.0 472815.0 697720.0 597538.0 572179.0 True False 467530.84689315327 562937.82574854 613955.1418978212 703371.4455660167 713072.3273381945 606568.2994060442 514894.61903597676 589903.406010578 629122.6387819954 552147.1873677339 0.8467503911810647 1.019543046904302 1.1119410837257833 1.2738839600346752 1.2914533364511793 1.098562689955469 0.9325314532355905 1.068380713524668 1.1394111084423495 1.0 19.07469337582451 -4.860062738266835 2.363041039716062 1.1212326553628864 0.8081254474209261 0.38647897033756295 0.10317548188580192 0.5430162135073126 4.277723114891355 0.03064229122605938 0.3319237372550152 1.380184868421491e-05 4.860062738266835 -0.31310720794196034 AGEPNS(ph)PDAEEANSPDVTAGCDPAGVHPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGEPNSPDAEEANSPDVTAGCDPAGVHPPR 30 0 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 AGEPNS(0.934)PDAEEANS(0.055)PDVT(0.01)AGCDPAGVHPPR 54.097 0.0014112999999999999 17663000.0 7096.3 7572.2 8395.1 9925.9 8019.1 6190.6 7379.5 7832.4 6689.3 2688.6 True False 8297.563431686242 8323.917973073589 8595.271022594045 9369.784003201987 6447.814920591015 5865.954038071537 6680.460337046653 7626.807799113779 6787.118357587718 3176.0218970541096 2.6125649320562214 2.6208629042496097 2.7063009328010335 2.9501635400854274 2.0301544289010183 1.846950124466223 2.103404999582356 2.401371289721886 2.136987268218474 1.0 11.633005143825097 -6.276705728024118 22.553793834158256 1.99541630387791 2.7140599911101666 0.5404461314238265 0.35852447565061085 185.82993955371686 274535.44229244906 0.10725651104732402 0.12224044982928019 5.288034403576896e-07 6.276705728024118 0.7186436872322566 AGEPNS(ph)PDAEEANSPDVTAGCDPAGVHPPR ddPTM_PC-9_Lapatinib_30min_R1 2 AGEPNSPDAEEANSPDVTAGCDPAGVHPPR 30 0 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 AGEPNS(1)PDAEEANSPDVTAGCDPAGVHPPR;AGEPNS(1)PDAEEANSPDVTAGCDPAGVHPPR 160.22 4.8717e-16 451780000.0 230166.3 310583.0 357476.0 299470.0 335114.6 368470.0 287390.8 285942.3 365423.4 247530.8 True False 226884.08635467023 309863.86414566287 328085.70317726565 321494.02280263434 315403.81808865303 352711.3970455228 302270.4894100155 299228.2231416874 324265.56861300475 290316.1689659416 0.7815068901012093 1.0673324370783306 1.1300979354537948 1.1073927571714077 1.0864149220901802 1.2149216431927397 1.04117690201911 1.0306977534440782 1.1169394035750242 1.0 18.147265398579755 -4.763151482959969 4.522479223488831 1.0954132924632456 0.7558744333423922 0.7240365502927859 0.05693633843243951 0.10287491271580082 4.681404194826939 0.01414841872437661 0.11381395063930487 1.7252360205552367e-05 4.763151482959969 -0.33953885912085335 AGEPNSPDAEEANS(ph)PDVTAGCDPAGVHPPR ddPTM_PC-9_AZD4547_30min_R2 1 AGEPNSPDAEEANSPDVTAGCDPAGVHPPR 30 0 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 AGEPNS(0.362)PDAEEANS(0.628)PDVT(0.01)AGCDPAGVHPPR 50.088 0.010456 6309000.0 10132.0 10138.0 13420.0 20541.0 16445.0 16122.0 11712.0 18617.0 13089.0 12851.0 True False 13353.765241307978 13414.910240604657 13242.042031527777 15805.58980528643 14161.895611362641 15113.88879138623 12754.34531084962 15740.170426100636 13780.857818276885 12401.090401539968 1.0768218607332873 1.0817524754870582 1.0678127166852505 1.2745322623665167 1.141987934351645 1.218754827358519 1.028485794222239 1.2692569698666192 1.1112617819934267 1.0 13.598179358849652 AGEPNSPDAEEANS(ph)PDVTAGCDPAGVHPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AGEPNSPDAEEANSPDVTAGCDPAGVHPPR 30 0 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 AGEPNSPDAEEANS(0.958)PDVT(0.042)AGCDPAGVHPPR;AGEPNSPDAEEANS(1)PDVTAGCDPAGVHPPR;AGEPNSPDAEEANS(1)PDVTAGCDPAGVHPPR;AGEPNSPDAEEANS(0.965)PDVT(0.035)AGCDPAGVHPPR 129.97 3.3747e-17 596602100.0 204182.1 246873.0 287584.0 293203.0 328412.0 254879.0 270058.0 277464.0 260511.0 218244.0 True False 238746.09674970098 271380.9199131825 294441.09322839393 276775.7864869509 264062.0261252684 241512.6965511638 244476.15118939613 270180.8639974091 264320.48053660785 257809.90958144676 0.926054770886442 1.0526395992837057 1.1420860187508608 1.073565352613075 1.0242508775321009 0.9367859324851344 0.9482806599106376 1.0479847901736847 1.0252533774428259 1.0 17.9759481928658 -6.52456372451859 24.963577773976844 0.9906786926430126 1.0547236967591123 0.17339638614551023 0.05815111902423498 94.05163682242637 1393366.7920846054 0.020495510064040007 0.020644957026602184 2.988383125965148e-07 6.52456372451859 0.0640450041160997 AGEPNSPDAEEANS(ph)PDVTAGCDPAGVHPPR ddPTM_PC-9_Lapatinib_30min_R1 4 AGEPNSPDAEEANSPDVTAGCDPAGVHPPR 30 0 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 AGEPNSPDAEEANS(1)PDVTAGCDPAGVHPPR;AGEPNSPDAEEANS(0.987)PDVT(0.013)AGCDPAGVHPPR;AGEPNS(0.412)PDAEEANS(0.587)PDVT(0.001)AGCDPAGVHPPR;AGEPNSPDAEEANS(0.995)PDVT(0.004)AGCDPAGVHPPR 153.77 3.3676e-17 480298200.0 382478.8 617235.5 674095.5 678890.6 646434.3 624377.2000000001 597619.9 532223.2000000001 705831.2000000001 406804.6 True False 377024.5821739778 615806.3291225857 618673.9700738802 728818.4794366535 608412.3054127323 597674.0426503426 628561.734245371 556952.2328483155 626333.0575239556 477120.23307694413 0.7902087483118241 1.2906732652087634 1.296683576137732 1.5275363082728848 1.2751760735215247 1.2526696652454834 1.3174074178153836 1.1673205079913203 1.312736316975575 1.0 18.863993341938723 -10.484479024574565 14.707650696865109 0.9999948123563767 1.2593736015480754 0.14877759484739395 0.17589273325250465 0.0 0.0 0.16973113872715664 0.041165847819319486 3.277336052029064e-11 10.484479024574565 0.25937878919169877 AGFAGDDAPR ddPTM_PC-9_AZD4547_30min_R2 6 AGFAGDDAPR 10 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;Q6S8J3;C9JTX5;A5A3E0;P63267-2;P0CG38;P0CG39;F8WCH0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;POTEE;POTEF;ACTG2;POTEI;POTEJ;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Actin, gamma-enteric smooth muscle;POTE ankyrin domain family member I;POTE ankyrin domain family member J;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 0 ;;;;; 141.52 0.00057358 718726000.0 873723.0 841998.0 1246725.0 1565227.0 1306382.0 1080531.0 996953.0 1302499.0 917610.0 1101973.0 False True 1151548.7394326194 1114157.3873316857 1230192.611904357 1204388.0976660862 1125013.4090947504 1012965.2257564435 1085679.88564613 1101227.707999445 966112.9912620578 1063393.2606844762 1.0829001668596245 1.0477378675641917 1.1568557535455104 1.1325895528911436 1.057946717069291 0.9525781883406204 1.0209580272751668 1.0355789797751924 0.9085190088944123 1.0 20.02024379772432 -6.5610524644053525 4.877744666045926 0.9886141337055672 1.1039785328587097 0.6419455166548351 0.0428834228967332 0.13355392318235756 7.539139846034445 0.014676095269425215 0.014961561056236283 2.7475622172129573e-07 6.5610524644053525 0.11536439915314256 AGFAGDDAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 AGFAGDDAPR 10 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;Q6S8J3;C9JTX5;A5A3E0;P63267-2;P0CG38;P0CG39;F8WCH0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;POTEE;POTEF;ACTG2;POTEI;POTEJ;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Actin, gamma-enteric smooth muscle;POTE ankyrin domain family member I;POTE ankyrin domain family member J;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 0 ;;;;; 167.23 0.00052993 454687000.0 851946.0 887429.0 982627.0 998052.0 1070568.0 1005362.0 957853.0 978377.0 902149.0 741127.0 False True 996163.6310994964 975527.0863060583 1006056.5543136516 942134.38216824 860797.885536692 952639.0468813492 867118.2295848163 952695.6404261211 915341.2224267711 875487.4583418943 1.1378388366478183 1.1142673455923988 1.149138739484681 1.0761255037879924 0.983221264148063 1.0881241504996246 0.9904404926908619 1.0881887928245746 1.0455217989762602 1.0 19.739726986142415 -5.954288551512267 4.93942133916175 1.0368838347489178 1.1306178272366672 0.6204551330861237 0.03528717374290164 0.1285149095791142 7.083883026076792 0.009587334851687524 0.014256741121166764 1.1109933220318537e-06 5.954288551512267 0.09373399248774938 AGFAGDDAPR ddPTM_PC-9_Lapatinib_30min_R1 6 AGFAGDDAPR 10 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;Q6S8J3;C9JTX5;A5A3E0;P63267-2;P0CG38;P0CG39;F8WCH0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;POTEE;POTEF;ACTG2;POTEI;POTEJ;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Actin, gamma-enteric smooth muscle;POTE ankyrin domain family member I;POTE ankyrin domain family member J;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 0 ;;;;; 154.12 0.0009734 1276190000.0 1397742.0 1345526.0 1412961.0 1283152.0 1294584.0 1409307.0 1317326.0 1262769.0 1403232.0 1173270.0 False True 1377809.9427655116 1342410.5172158715 1296792.8007671866 1377519.2785495936 1218439.1143700706 1349034.2248650754 1385530.694554377 1321441.8577048793 1245185.2354719595 1376068.1562159928 1.0012657705518806 0.9755407180610332 0.9423899498795154 1.0010545424854473 0.8854496842079528 0.9803542206621094 1.0068765041147418 0.9603026214476696 0.9048863094805244 1.0 20.392120497358142 -4.886563029483563 3.385814691844989 0.9598252706634137 1.0025036071376876 0.09654507753795094 0.03850324713328401 0.654090311272229 12.846487330700564 0.009694755943153622 0.06207931544079321 1.298485100038063e-05 4.886563029483563 0.04267833647427388 AGFNYESPS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 2 AGFNYESPSK 10 0 Q9UHF7;Q9UHF7-3;Q9UHF7-2;H0YC29;E5RJ97;E7EVN4;F8W8T0 Q9UHF7 TRPS1 Zinc finger transcription factor Trps1 1 AGFNYES(0.356)PS(0.644)K;AGFNYES(0.031)PS(0.969)K 99.215 0.012293 4984700.0 29693.0 54543.0 42027.0 42038.0 46215.0 43632.0 47439.0 43509.0 36327.0 43062.0 True False 29269.57237497068 54416.70903461191 38571.70228891146 45129.61475465707 43496.72456218591 41765.96107115977 49895.15929919028 45530.58697741354 32235.470719731253 50505.20932349178 0.5795357106134467 1.0774474507385272 0.7637173037310903 0.8935635622376418 0.8612324380953319 0.8269634287355172 0.9879210475023664 0.9015027872824921 0.6382603131740191 1.0 15.62414458083103 -4.732887613263631 24.656828646448435 0.8777101548997952 0.5795337226437561 0.3700138303926719 0.11873964265119641 3028.497628381578 2615192.8209684705 0.027891542538573545 2.8441282236981182 1.849747234680756e-05 4.732887613263631 -0.29817643225603907 AGGAS(ph)PAASSTAQPPTQHR ddPTM_PC-9_AZD4547_30min_R2 7 AGGASPAASSTAQPPTQHR 19 0 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 AGGAS(1)PAASSTAQPPTQHR;AGGAS(1)PAASSTAQPPTQHR;AGGAS(1)PAASSTAQPPTQHR;AGGAS(1)PAASSTAQPPTQHR;AGGAS(1)PAASSTAQPPTQHR;AGGAS(1)PAASSTAQPPTQHR;AGGAS(1)PAASSTAQPPTQHR 169.06 8.9246e-28 448631700.0 67304.8 66303.7 110945.5 176844.8 144329.90000000002 111445.29999999999 92719.5 141311.90000000002 95938.7 121255.4 True False 88706.32637319245 87735.07438547826 109474.29017949809 136075.9635849238 124292.18470042016 104476.60777339539 100971.35587852812 119475.39287941607 101009.82381926215 117010.28535327109 0.758107085247892 0.7498065159023696 0.9355954465795828 1.162940190890832 1.062232985118906 0.8928839670629406 0.8629271826291244 1.021067443077354 0.8632559395466713 1.0 16.836275824552942 -5.313749260988479 4.538655062249592 0.9808107071270048 0.7520143665623322 0.5045783876377998 0.0882810969410511 0.16903118593715327 7.534873346288562 0.025333939547785202 0.0578993278705707 4.855687613598375e-06 5.313749260988479 -0.22879634056467257 AGGAS(ph)PAASSTAQPPTQHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 AGGASPAASSTAQPPTQHR 19 0 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 AGGAS(0.772)PAAS(0.056)S(0.012)T(0.012)AQPPT(0.147)QHR;AGGAS(1)PAASSTAQPPTQHR;AGGAS(1)PAASSTAQPPTQHR;AGGAS(1)PAASSTAQPPTQHR;AGGAS(1)PAASSTAQPPTQHR 161.97 1.7888e-06 327527100.0 93947.0 91166.3 120708.6 128595.4 160259.6 127618.4 125946.0 118009.0 126686.7 100529.1 True False 109850.37156216984 100216.68776691314 123586.75081391455 121390.61664991207 128857.88181316422 120925.86644464651 114015.48310992305 114911.38879087102 128539.25331981033 118754.23004208232 0.9250228099095311 0.843899941344404 1.040693462204418 1.0222003595736802 1.0850803526535562 1.0182868130406357 0.9600961841066207 0.9676403842637897 1.0823972609166053 1.0 16.857619377792354 -5.266748154292912 24.99860432618384 1.0208031650232507 0.8844613721263496 0.6199020685602472 0.04308613754591534 262.11987892803495 1234307.077546013 0.011639275472527695 0.02542568177314569 5.410679952467338e-06 5.266748154292912 -0.13634179289690118 AGGAS(ph)PAASSTAQPPTQHR ddPTM_PC-9_Lapatinib_30min_R1 6 AGGASPAASSTAQPPTQHR 19 0 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 AGGAS(1)PAASSTAQPPTQHR;AGGAS(1)PAASSTAQPPTQHR;AGGAS(1)PAASSTAQPPTQHR;AGGAS(1)PAASSTAQPPTQHR;AGGAS(1)PAASSTAQPPTQHR;AGGAS(1)PAASSTAQPPTQHR 216.34 1.8692999999999997e-86 358596400.0 63844.100000000006 50657.0 74591.1 58384.1 60452.6 65907.9 47881.7 56722.5 69389.7 51570.8 True False 62933.67142642601 50539.706828856804 68458.50768797245 62677.86147764812 56896.89692238447 63089.17275581886 50360.78013904253 59358.03442566692 61574.30128006532 60484.744066228435 1.0404883478967208 0.8355777578147275 1.1318309888690783 1.0362590177949387 0.940681783493778 1.043059266097558 0.8326195459122624 0.9813720028421082 1.0180137525694721 1.0 15.884283680027805 AGGEEEDDDDEAAGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGGEEEDDDDEAAGGR 16 0 Q6DD87 Q6DD87 ZNF787 Zinc finger protein 787 0 179.93 5.4488e-29 0.0 1291.9 3100.7 3041.6 1269.5 3415.4 905.75 2738.1 735.22 767.46 817.5 False True 1510.5931538119105 3408.5170041875926 3114.1232793322365 1198.3740307745318 2746.176887654043 858.2508755182532 2478.727345872679 715.9212540299822 778.6826506083256 965.7062786735605 1.564236649560543 3.5295587068868794 3.2247106062203716 1.2409301432942432 2.8436978699424387 0.888728689531871 2.5667507819016344 0.7413447233804166 0.8063348740756662 1.0 9.915440647224242 -7.03365046624305 0.6134857911030697 0.8099689524320812 2.741843255800798 0.3679514381210881 0.8196197348974451 0.8337063681175034 0.6601850852367908 0.6881754948247379 0.5979666045635554 9.254426994645718e-08 7.03365046624305 1.931874303368717 AGGEEEDDDDEAAGGR ddPTM_PC-9_Lapatinib_30min_R1 1 AGGEEEDDDDEAAGGR 16 0 Q6DD87 Q6DD87 ZNF787 Zinc finger protein 787 0 185.57 3.0090999999999996e-07 2473300.0 1270.3 2148.3 3023.9 3093.2 4206.3 3337.5 3914.2 4498.9 3191.6 2166.5 False True 1252.1852890555099 2143.3257433411595 2775.286614591558 3320.6842466127137 3958.893703903981 3194.7629050924925 4116.85812367231 4707.935318041919 2832.128398962046 2540.976638320211 0.4927968522698834 0.8435047024903265 1.0922125661203421 1.3068535131468002 1.5580205044785957 1.2572972363903694 1.6201873175795443 1.8528054319910008 1.1145826200253104 1.0 11.311167396009862 -5.113569105472029 1.0191766775848412 1.4542911474156894 0.29234215923388657 0.6013167497096936 0.23875616864181184 0.7446883173495962 0.8991232289623233 0.07952128326877228 0.8385766324739095 7.698939281410507e-06 5.113569105472029 -1.1619489881818028 AGGFLMK ddPTM_PC-9_Lapatinib_30min_R1 1 AGGFLMK 7 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 120.06 0.028661000000000002 2892900.0 28335.0 34388.0 32658.0 30353.0 29327.0 33209.0 35938.0 36773.0 35470.0 26831.0 False True 27930.937703997402 34308.37669879241 29972.985303525602 32585.260874639756 27602.043519100425 31788.72848396002 37798.69379401552 38481.607826436586 31474.995084341324 31468.702599939774 0.8875783046756703 1.0902380417443098 0.9524696866143749 1.0354815477744583 0.8771268351925399 1.010169656121154 1.2011519596008975 1.222853331948621 1.0001999600835645 1.0 14.941630079596115 -7.087514905177918 6.519419249926226 1.123535047149871 0.974879034426384 0.33512216300454545 0.0900413194819692 0.25932905422286745 16.131267645895125 0.03353684660801304 0.026003870925202257 8.174949806743549e-08 7.087514905177918 -0.14865601272348705 AGGGDLLLPPS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 AGGGDLLLPPSPK 13 0 Q5TH69 Q5TH69 ARFGEF3 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 1 AGGGDLLLPPS(1)PK;AGGGDLLLPPS(1)PK 135.91 4.8778999999999995e-05 24189000.0 135147.0 160247.0 160547.0 206580.0 211120.0 179195.0 242010.0 211370.0 201489.0 203253.0 True False 178120.93476777038 212043.70894911973 158418.04188045353 158956.17262918415 181809.63219646562 167989.90832232093 263548.42116450734 178707.62329939794 212139.2971920541 196137.17433539836 0.9081446970536046 1.0810990301436731 0.8076900384501084 0.8104336833025136 0.9269514196506555 0.8564919367863174 1.3436943917313422 0.9111359124293513 1.0815863841766773 1.0 17.581503473233475 AGGGDLLLPPS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGGGDLLLPPSPK 13 0 Q5TH69 Q5TH69 ARFGEF3 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 1 AGGGDLLLPPS(1)PK;AGGGDLLLPPS(1)PK 148.41 9.814100000000001e-05 19712500.0 136701.0 167946.0 155320.0 252040.0 249410.0 207451.0 253460.0 220614.0 196586.0 192914.0 True False 159841.7793321789 184618.56896355312 159023.41785438027 237919.01592470537 200539.90090466526 196571.90436338648 229450.43390850947 214823.11625985507 199460.69834582714 227887.78109361645 0.7014056592464508 0.8101293017009618 0.6978145870359471 1.0440183092877984 0.8799940915756398 0.8625820279615369 1.0068571154073902 0.9426706216056647 0.8752584161758482 1.0 17.79796404656863 -5.750491458937983 24.999992960682945 0.9385935711867018 0.7438177562048633 0.6876524090426024 0.0641069522090426 126.47037467796638 288797.20218525006 0.017077258323223085 0.02921713338042218 1.776268200962727e-06 5.750491458937983 -0.1947758149818385 AGGGDLLLPPS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 AGGGDLLLPPSPK 13 0 Q5TH69 Q5TH69 ARFGEF3 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 1 AGGGDLLLPPS(1)PK;AGGGDLLLPPS(1)PK 145.61 9.886299999999999e-05 25267000.0 221880.0 196527.0 148893.0 186848.0 158439.0 151321.0 142011.0 143993.0 149756.0 108895.0 True False 218715.95051219122 196071.95380608257 136651.592283601 200589.4252266556 149119.92952305882 144849.35357647992 149363.63471484056 150683.4404522902 132888.9022794085 127717.35565653311 1.7124998351858944 1.5352021093622832 1.069953191413503 1.570572959293766 1.1675776464091778 1.1341399360476851 1.1694858067412561 1.1798196077400724 1.040492121029996 1.0 16.962595062267198 -1.5228787452811512 0.31908124863544157 1.0639054541876911 7.149399803398965 0.6608382925881235 0.1387733121877866 35.53495924045342 0.5072164566772307 0.13019691099834482 126.0651896679573 0.029999999999943797 1.5228787452811512 6.085494349211274 AGGGGGLGAGS(ph)PALSGGQGR ddPTM_PC-9_AZD4547_30min_R2 6 AGGGGGLGAGSPALSGGQGR 20 0 A0A3B3ITT1;Q6IQ22 A0A3B3ITT1 RAB12 Ras-related protein Rab-12 1 AGGGGGLGAGS(1)PALSGGQGR;AGGGGGLGAGS(0.934)PALS(0.066)GGQGR;AGGGGGLGAGS(0.995)PALS(0.005)GGQGR;AGGGGGLGAGS(0.943)PALS(0.057)GGQGR;AGGGGGLGAGS(0.985)PALS(0.015)GGQGR;AGGGGGLGAGS(1)PALSGGQGR 214.46 1.0414999999999999e-37 285850400.0 107584.2 158017.1 257533.8 267444.0 250654.0 229702.6 256175.3 302010.3 245045.5 209037.6 True False 141793.7377096252 209093.03738219105 254118.73354240417 205788.91776861015 215855.01870297908 215339.26010992876 278974.40542268544 255341.5476412845 257998.1048596964 201719.2572500932 0.7029261342848797 1.0365546662853105 1.259764372557379 1.0201748736040177 1.070076410381386 1.0675195965199762 1.3829835050245634 1.2658263327070949 1.278995909348547 1.0 17.621989292711135 -4.810405140053762 2.832473208449847 1.172912914009191 0.6342463968091573 0.5716173411985127 0.12147071159373708 0.2950753255270717 3.452555699361942 0.03319859608909181 0.3621338865897336 1.547372448923338e-05 4.810405140053762 -0.5386665172000337 AGGGGGLGAGS(ph)PALSGGQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 AGGGGGLGAGSPALSGGQGR 20 0 A0A3B3ITT1;Q6IQ22 A0A3B3ITT1 RAB12 Ras-related protein Rab-12 1 AGGGGGLGAGS(0.998)PALS(0.002)GGQGR;AGGGGGLGAGS(0.919)PALS(0.081)GGQGR;AGGGGGLGAGS(1)PALSGGQGR;AGGGGGLGAGS(0.999)PALS(0.001)GGQGR;AGGGGGLGAGS(0.995)PALS(0.005)GGQGR;AGGGGGLGAGS(0.999)PALS(0.001)GGQGR 238.45 1.8945e-44 273332600.0 161423.0 230567.0 271716.0 234174.0 339425.0 249470.0 229695.0 199997.0 207780.0 210104.0 True False 188748.72565042172 253456.16799578132 278194.7399286679 221053.98998235192 272917.1078327493 236387.35403316407 207936.6267522096 194747.29066433804 210818.38941885898 248194.1920176506 0.7604880844149594 1.0212010439702655 1.1208753019848416 0.890649326583079 1.0996111779011353 0.9524290319265534 0.8377981171188 0.7846569215869821 0.8494090361464477 1.0 17.921109829851204 -7.166626351063047 4.621734671986982 0.8502988423580586 0.9871972051591192 0.17685727153398778 0.10936155654369346 0.32233026311602414 11.610361281326623 0.04235742306047518 0.03230698219995158 6.813553164098337e-08 7.166626351063047 0.1368983628010606 AGGGGGLGAGS(ph)PALSGGQGR ddPTM_PC-9_Lapatinib_30min_R1 5 AGGGGGLGAGSPALSGGQGR 20 0 A0A3B3ITT1;Q6IQ22 A0A3B3ITT1 RAB12 Ras-related protein Rab-12 1 AGGGGGLGAGS(0.994)PALS(0.006)GGQGR;AGGGGGLGAGS(0.95)PALS(0.05)GGQGR;AGGGGGLGAGS(1)PALSGGQGR;AGGGGGLGAGS(1)PALSGGQGR;AGGGGGLGAGS(0.984)PALS(0.016)GGQGR 197.94 1.3244000000000002e-15 292876100.0 360810.0 465676.0 286193.0 239048.8 218080.0 195676.1 154154.3 196413.2 255017.0 119831.2 True False 355664.7832355499 464597.75583304843 262663.316276927 256629.24619542013 205252.96316177622 187307.48934626806 162135.6553712172 205539.2743136388 226294.30001193876 140543.86325496295 2.5306318966793486 3.30571356922368 1.868906334248299 1.825972619877858 1.4604192485403893 1.332733319038416 1.1536302732555759 1.4624564143420946 1.6101329134621447 1.0 17.100660935306124 -5.5553521219474735 1.6766280651252237 1.3679801620586673 2.9494506044119158 0.8056656571832608 0.2900020633484057 0.15339731695121697 0.836518477560087 0.08436656415919992 0.2370796294581417 2.783863122890751e-06 5.5553521219474735 1.5814704423532484 AGGGGGLGAGS(ph)PALSGGQGRR ddPTM_PC-9_Lapatinib_30min_R1 1 AGGGGGLGAGSPALSGGQGRR 21 1 A0A3B3ITT1;Q6IQ22 A0A3B3ITT1 RAB12 Ras-related protein Rab-12 1 AGGGGGLGAGS(0.996)PALS(0.004)GGQGRR 125.61 9.6866e-07 0.0 35854.0 13323.0 10351.0 10036.0 6527.2 6769.4 5481.3 5335.8 11783.0 4608.4 True False 35342.715385181655 13292.151412062682 9499.980736015483 10774.080919114565 6143.2829289689425 6479.8885422421345 5765.094893793121 5583.72074729558 10455.874459509263 5404.955799692984 6.538946236561123 2.459252564621844 1.757642631703872 1.9933707727501788 1.1366018810584717 1.198879099549752 1.0666312746018374 1.033074266326609 1.9344976808326877 1.0 12.40006710468964 -3.0731917464464975 1.0795978812649039 1.294644108144822 199.99999999999997 0.9518037335554551 0.3475892571351709 11.968787198466833 0.47541836791639674 0.10877754861096865 5466.373415901785 0.0008449057263506434 3.0731917464464975 198.70535589185516 up AGGGPTLQCPPPS(ph)SPEK ddPTM_PC-9_AZD4547_30min_R2 1 AGGGPTLQCPPPSSPEK 17 0 Q96N66-3;Q96N66-2;Q96N66 Q96N66-3 MBOAT7 Lysophospholipid acyltransferase 7 1 AGGGPTLQCPPPS(0.694)S(0.306)PEK 142.57 0.00010998 5538000.0 42318.0 41279.0 45667.0 35097.0 41027.0 27718.0 46222.0 44722.0 39128.0 31919.0 True False 55774.243730918985 54621.62949515875 45061.42574171227 27005.928893244636 35331.10922756918 25984.789078256028 50335.66845612113 37811.24250932336 41196.2261986048 30801.525525387467 1.810762382043328 1.7733416953695391 1.4629608427859004 0.8767724465785178 1.147057122169105 0.8436201985138252 1.6341940081712214 1.2275769418679698 1.3374735665170134 1.0 14.910714185450422 -5.4617744210375125 3.667025238790439 1.167699169632993 1.7831797811393304 0.5775516752192928 0.2184217795396958 0.17146194485525276 4.523706211530457 0.061149256940580675 0.13317695629330126 3.453230586536359e-06 5.4617744210375125 0.6154806115063374 AGGGPTLQCPPPS(ph)SPEK ddPTM_PC-9_Lapatinib_30min_R1 2 AGGGPTLQCPPPSSPEK 17 0 Q96N66-3;Q96N66-2;Q96N66 Q96N66-3 MBOAT7 Lysophospholipid acyltransferase 7 1 AGGGPTLQCPPPS(0.867)S(0.133)PEK;AGGGPTLQCPPPS(0.985)S(0.015)PEK 160.63 2.9869e-05 28931200.0 79189.0 138878.0 50481.0 34976.0 45701.0 46156.0 47310.0 46781.0 67410.0 20081.1 True False 78059.75033851595 138556.43652363887 46330.64704229518 37548.251716515675 43012.95703162303 44182.015474891115 49759.48031039214 48954.6160424368 59817.57594123056 23552.091378616184 3.3143447468698803 5.882978046248555 1.9671563895323747 1.5942640130297356 1.82629034255005 1.8759274819647482 2.11274147635019 2.0785676845192826 2.5397989070109146 1.0 14.523567553510336 -5.281028143347399 24.296763926128943 1.9097150793261433 4.598661109423736 0.7160898574039053 0.6858693295447267 230.4856148661608 285880.82212944643 0.16511962317105852 0.3446071786410125 5.23566507092862e-06 5.281028143347399 2.6889460300975925 AGGGPTLQCPPPSS(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 2 AGGGPTLQCPPPSSPEK 17 0 Q96N66-3;Q96N66-2;Q96N66 Q96N66-3 MBOAT7 Lysophospholipid acyltransferase 7 1 AGGGPTLQCPPPS(0.01)S(0.99)PEK;AGGGPTLQCPPPS(0.21)S(0.79)PEK 192.23 3.5147e-09 44267000.0 148887.0 151145.0 193053.0 140138.0 159820.0 108793.0 182033.0 168255.0 167155.0 127103.0 True False 196229.96895801582 199999.66544843078 190492.9910814107 107831.34921051697 137631.75169400923 101990.15651167861 198233.58435535233 142255.05586526083 175990.4720463041 122653.1626571424 1.5998769596063804 1.6306115644771293 1.553102969011112 0.8791566957954645 1.1221215067950356 0.8315330343072851 1.6162125791202229 1.1598156360868772 1.4348628949606277 1.0 16.904224909236923 -5.637599914582501 7.712278613124728 1.161548420085043 1.6087747731196274 0.45576594339641474 0.2233178785518133 0.21340759054149666 13.489462125657095 0.06153729404570396 0.10691175657483357 2.303562953184693e-06 5.637599914582501 0.44722635303458436 AGGGPTLQCPPPSS(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AGGGPTLQCPPPSSPEK 17 0 Q96N66-3;Q96N66-2;Q96N66 Q96N66-3 MBOAT7 Lysophospholipid acyltransferase 7 1 AGGGPTLQCPPPS(0.029)S(0.971)PEK;AGGGPTLQCPPPS(0.079)S(0.921)PEK;AGGGPTLQCPPPS(0.231)S(0.769)PEK 242.1 2.1218000000000001e-38 42337000.0 180004.0 205535.0 124685.0 138905.0 229287.0 117365.0 150394.0 100029.0 110517.0 115541.0 True False 210475.1219589436 225939.15646650657 127657.96327049562 131122.60318608594 184359.85830050192 111210.17279072564 136147.5915617312 97403.34473948606 112133.10204737743 136487.66867794737 1.5420815960713274 1.6553814616002163 0.9353076692350422 0.9606919398372853 1.3507436978465248 0.8148001491118891 0.997508367462715 0.7136420871054393 0.8215621464819923 1.0 17.058411087554063 -4.303313966914781 0.5243431311592229 0.8664654639008538 2.66816785254015 0.6099910782492233 0.19122489056801373 4.4785462139066174 0.6505618096623341 0.11054483671639816 5.499033366752975 4.9737738318805895e-05 4.303313966914781 1.8017023886392962 AGGGPTLQCPPPSS(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 2 AGGGPTLQCPPPSSPEK 17 0 Q96N66-3;Q96N66-2;Q96N66 Q96N66-3 MBOAT7 Lysophospholipid acyltransferase 7 1 AGGGPTLQCPPPS(0.232)S(0.768)PEK;AGGGPTLQCPPPS(0.027)S(0.973)PEK 201.4 8.428799999999999e-13 31535700.0 102791.0 165779.0 57350.0 42697.0 58990.0 60460.0 68008.0 55252.0 86594.0 21215.0 True False 101325.18149043928 165395.1489109315 52634.90437740195 45837.07981301662 55520.324178802264 57874.266739143706 71529.12147430031 57819.209627342694 76840.8718447548 24881.984482789416 4.072230716184425 6.64718479449794 2.115382091561423 1.842179422815797 2.2313463066904906 2.325950600088778 2.874735394348316 2.3237378701580487 3.0882131567080093 1.0 14.602813932916092 -5.274716462106763 24.911752620149496 2.2858064437888386 5.3597077202492525 0.7170703088419659 0.7868324964761474 309.8874616191343 581441.126583077 0.19194477042284225 0.4032939880455733 5.312311559916863e-06 5.274716462106763 3.073901276460414 AGGIETIANEFSDR ddPTM_PC-9_AZD4547_30min_R2 2 AGGIETIANEFSDR 14 0 Q92598-2;Q92598-3;Q92598;R4GN69 Q92598-2 HSPH1 Heat shock protein 105 kDa 0 ; 150.14 9.4571e-05 10740300.0 23513.2 19210.1 38350.0 61728.0 47462.0 40661.0 37476.0 45568.0 30086.1 44319.0 False True 30989.90849505752 25419.389151019866 37841.453942555156 47497.56328809312 40872.720553754545 38118.46124218806 40811.29139936817 38526.51264846938 31676.389824009515 42767.40529965372 0.7246151193396911 0.5943636040792422 0.8848199622449752 1.1106019398487497 0.9556979261981433 0.8912970280779857 0.9542615717137886 0.9008382056037738 0.7406666268871352 1.0 15.38422406104766 -5.356588812274915 5.289247931274932 0.9358251316594258 0.6612247961690316 0.578884109350629 0.0927704338181285 0.14617951093442377 6.287578948900827 0.025204581600031528 0.05425112176023895 4.399579681904605e-06 5.356588812274915 -0.2746003354903942 AGGIETIANEFSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGGIETIANEFSDR 14 0 Q92598-2;Q92598-3;Q92598;R4GN69 Q92598-2 HSPH1 Heat shock protein 105 kDa 0 ; 102.62 0.006524500000000001 2624900.0 16579.8 12702.5 19138.9 20691.3 23671.0 23460.0 22654.0 17948.800000000003 21342.1 16136.2 False True 19386.4326740233 13963.520252102066 19595.24396068244 19532.033543099686 19032.83747369529 22229.716301030323 20508.049119243155 17477.663018325602 21654.18783721358 19061.56532591109 1.0170430571969138 0.7325484561921541 1.0279976290323807 1.0246815101039508 0.9984928912329802 1.1662062333785697 1.075884837818949 0.9169059686072879 1.1360130958278774 1.0 14.218378977034558 -5.422953445420132 9.57350151770597 1.0448115242287925 0.8749862533327434 0.3484321343498171 0.09241831976894627 0.39978746551395306 35.753547686102365 0.023077177696854224 0.04809860229402459 3.7761266727870625e-06 5.422953445420132 -0.16982527089604915 AGGIETIANEFSDR ddPTM_PC-9_Lapatinib_30min_R1 2 AGGIETIANEFSDR 14 0 Q92598-2;Q92598-3;Q92598;R4GN69 Q92598-2 HSPH1 Heat shock protein 105 kDa 0 ; 193.15 7.776000000000001e-07 10590500.0 21071.7 22859.3 21493.1 21037.5 19544.2 19766.8 17541.0 17269.3 18115.2 20258.9 False True 20771.21369392348 22806.370695321217 19726.020283765265 22584.667929042706 18394.648581375593 18921.42004266137 18449.18715122784 18071.694722679178 16074.87541448716 23760.62387171258 0.8741863768422325 0.9598388837960009 0.8301979102177288 0.950508204287099 0.7741652189223335 0.7963351528487279 0.7764605530072762 0.760573241689745 0.6765342316463571 1.0 14.536285096361933 -6.273258036268983 24.467861414419808 0.7842786994487908 0.9024450654977352 0.2698642869888904 0.08404617027399217 649.9132325738624 1345496.117098954 0.024424179194569625 0.027919835201094974 5.330181084296218e-07 6.273258036268983 0.11816636604894437 AGGIETIANEYSDR ddPTM_PC-9_Lapatinib_30min_R1 2 AGGIETIANEYSDR 14 0 A0A087WYC1;P34932;A0A087WTS8;P34932-2 A0A087WYC1 HSPA4 Heat shock 70 kDa protein 4 0 ; 103.44 0.0055887 6471100.0 18334.9 21870.9 35316.0 28088.0 28813.0 31246.0 27108.0 27642.0 35390.0 30553.0 False True 18073.440963791145 21820.259274794094 32412.454803702316 30153.68521882124 27118.275988537545 29909.681417983546 28511.51959953731 28926.34823208224 31404.005526778663 35834.04534068651 0.5043650749436958 0.6089253688033666 0.9045156497276831 0.8414814719393205 0.7567740602746587 0.8346721988439202 0.7956545047724463 0.8072308877512869 0.8763734383938528 1.0 15.129043299556596 -5.112184455097427 3.9999433837364906 0.8382988530030459 0.5235366081939431 0.7684685020317462 0.06545396138842888 0.099433486437558 2.6848679977948646 0.016299349079034527 0.05149607925706901 7.723524791307619e-06 5.112184455097427 -0.31476224480910275 AGGKPSQS(ph)PSQEAAGEAVLGAK ddPTM_PC-9_AZD4547_30min_R2 2 AGGKPSQSPSQEAAGEAVLGAK 22 1 P00519-2;P00519 P00519-2 ABL1 Tyrosine-protein kinase ABL1 1 AGGKPS(0.028)QS(0.945)PS(0.027)QEAAGEAVLGAK;AGGKPS(0.034)QS(0.686)PS(0.28)QEAAGEAVLGAK 106.1 1.7262000000000002e-05 11950800.0 57425.0 54159.0 63935.0 90004.0 81652.0 71226.0 58608.0 72812.0 58790.0 71905.0 True False 75684.95548579849 71664.8376130309 63087.18012561314 69254.96834793834 70316.02921611312 66772.22696038196 63823.99846125977 61560.57845330828 61897.51937783628 69387.62783617851 1.0907557708196587 1.0328186716834995 0.9091992635136558 0.9980881391628869 1.0133799267807013 0.9623073888334761 0.9198181354743205 0.8871981990600747 0.8920541212905263 1.0 16.08239082548552 -7.049612520436792 2.6735822337278554 0.9150448515154289 1.0040363639877514 0.36835034947271095 0.0510765323046301 0.31309648537263796 4.438516132995901 0.02212387731489658 0.01716598936590379 8.920464712157903e-08 7.049612520436792 0.08899151247232251 AGGKPSQS(ph)PSQEAAGEAVLGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGGKPSQSPSQEAAGEAVLGAK 22 1 P00519-2;P00519 P00519-2 ABL1 Tyrosine-protein kinase ABL1 1 AGGKPS(0.053)QS(0.926)PS(0.021)QEAAGEAVLGAK;AGGKPS(0.196)QS(0.752)PS(0.053)QEAAGEAVLGAK 76.329 0.00038228 11185100.0 76089.0 74283.0 78548.0 95253.0 101017.0 91753.0 93572.0 83336.0 89896.0 67137.0 True False 88969.36487374763 81657.32532075564 80420.88221494883 89916.28322439255 81223.44400660192 86941.31115807478 84708.1827573859 81148.51830179067 91210.5589334766 79308.40664380051 1.1218150589424598 1.029617524501594 1.0140272086935853 1.1337547560151526 1.0241467133667488 1.0962433219539525 1.068085797484717 1.0232019748707686 1.1500742833371054 1.0 16.27518617839808 AGGKPSQS(ph)PSQEAAGEAVLGAK ddPTM_PC-9_Lapatinib_30min_R1 2 AGGKPSQSPSQEAAGEAVLGAK 22 1 P00519-2;P00519 P00519-2 ABL1 Tyrosine-protein kinase ABL1 1 AGGKPS(0.017)QS(0.975)PS(0.008)QEAAGEAVLGAK;AGGKPS(0.016)QS(0.94)PS(0.044)QEAAGEAVLGAK 117.53 6.1219e-07 11292300.0 77423.0 69731.0 71398.0 56467.0 66235.0 59710.0 53204.0 51051.0 66543.0 49800.0 True False 76318.93382236073 69569.54215375979 65527.93204425009 60619.77154839005 62339.18752302036 57156.34249080831 55958.64279082867 53423.01583083823 59048.226611145255 58407.86364567108 1.3066551155739308 1.1910989002405665 1.1219025650685088 1.0378700360646198 1.0673081265426603 0.9785727284521982 0.9580669330811257 0.9146545087648946 1.0109636430012046 1.0 15.833874996580798 -4.53363625199673 0.5267887030372567 0.9604367967904517 1.6336551699207924 0.916213784545651 0.03256050373778489 1.3923896397372686 0.2443248234756171 0.01911729396806776 0.6106686412852451 2.9266025589878863e-05 4.53363625199673 0.6732183731303407 AGGLDWPEATEVS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 4 AGGLDWPEATEVSPSR 16 0 Q9Y446;Q9Y446-2;E9PKC4;E9PK71;E9PJR7;E9PRW6 Q9Y446 PKP3 Plakophilin-3 1 AGGLDWPEATEVS(0.996)PS(0.004)R;AGGLDWPEAT(0.001)EVS(0.985)PS(0.014)R;AGGLDWPEATEVS(0.978)PS(0.022)R;AGGLDWPEAT(0.002)EVS(0.913)PS(0.085)R 300.56 2.803899999999999e-112 193930000.0 161851.0 165808.0 219378.0 283550.0 291401.0 245135.0 205642.0 280996.0 214875.0 241399.0 True False 213316.25129006512 219402.19344783746 216468.90438096094 218181.92830382977 250945.001097397 229806.66969832906 223943.73961865937 237574.52484570927 226232.85382399306 232947.6944861366 0.9157259605450192 0.9418517488735856 0.9292596986567027 0.9366133834684267 1.0772590029317997 0.9865161799744944 0.9613477399407656 1.0198620998150638 0.9711744704022252 1.0 17.829646526411935 -6.041539399935435 24.998234325485427 1.0013671482307818 0.9306863872940545 0.5745495574714432 0.0303112572142582 362.13167912207797 217928.63379468297 0.008898077291372658 0.011488577756443675 9.087838489062963e-07 6.041539399935435 -0.07068076093672726 AGGLDWPEATEVS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 AGGLDWPEATEVSPSR 16 0 Q9Y446;Q9Y446-2;E9PKC4;E9PK71;E9PJR7;E9PRW6 Q9Y446 PKP3 Plakophilin-3 1 AGGLDWPEAT(0.13)EVS(0.85)PS(0.02)R;AGGLDWPEAT(0.058)EVS(0.893)PS(0.048)R;AGGLDWPEAT(0.008)EVS(0.989)PS(0.003)R;AGGLDWPEAT(0.36)EVS(0.591)PS(0.049)R;AGGLDWPEAT(0.002)EVS(0.882)PS(0.116)R 213.71 6.641900000000001e-22 126412100.0 74311.5 73951.8 94660.2 98484.7 117797.9 98985.3 107348.8 94682.9 93324.6 76249.7 True False 86890.96923097268 81293.24597358005 96917.25816880768 92966.92155070537 94716.24711430066 93794.33661433842 97179.94452599162 92197.57419982502 94689.29572220267 90073.16701770702 0.9646709681462764 0.9025245660297371 1.0759836850163735 1.0321267101936082 1.0515478721391118 1.0413127429603966 1.0789000514091784 1.0235853501376317 1.0512486554801408 1.0 16.45880976776276 -5.261815335747056 24.999980026091187 1.046128141447858 0.9335977624335641 0.7421799567048133 0.02609070210063751 13.552380050931427 901269.3012490164 0.006194376422364971 0.014313185892622912 5.47248606358924e-06 5.261815335747056 -0.11253037901429397 AGGLDWPEATEVS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 4 AGGLDWPEATEVSPSR 16 0 Q9Y446;Q9Y446-2;E9PKC4;E9PK71;E9PJR7;E9PRW6 Q9Y446 PKP3 Plakophilin-3 1 AGGLDWPEATEVS(0.719)PS(0.28)R;AGGLDWPEATEVS(0.975)PS(0.025)R;AGGLDWPEAT(0.001)EVS(0.979)PS(0.02)R;AGGLDWPEAT(0.004)EVS(0.972)PS(0.024)R 156.72 3.0137e-05 151882000.0 255024.0 251024.0 272146.0 226493.0 228414.0 212844.0 203226.0 204183.0 248943.0 175737.0 True False 251387.31099432576 250442.7693508688 249771.20639393918 243150.05077849957 214979.13759920222 203741.15828359753 213748.04788754482 213670.08758668808 220904.4178539942 206112.90629516664 1.2196582713472748 1.2150756294330205 1.21181740087761 1.1796934755278905 1.0430163809894495 0.988492967014047 1.0370434910147945 1.0366652502619078 1.0717641210572482 1.0 17.653075320240987 -6.217809753912429 3.2064497812792876 1.0277975448696524 1.2133974365248505 0.9441578494061521 0.021250338158827403 0.05643900971076431 1.1760616131328085 0.006985548065587707 0.008973887517548813 6.056061071382475e-07 6.217809753912429 0.1855998916551982 AGGLDWPEATEVSPS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGGLDWPEATEVSPSR 16 0 Q9Y446;Q9Y446-2;E9PKC4;E9PK71;E9PJR7;E9PRW6 Q9Y446 PKP3 Plakophilin-3 1 AGGLDWPEATEVS(0.455)PS(0.545)R 211.45 1.2095e-17 41190000.0 17178.0 16451.0 21592.0 21363.0 24206.0 24919.0 22092.0 24023.0 23709.0 16707.0 True False 20085.896119034736 18084.146559128614 22106.835168115995 20166.100369780474 19463.008064224916 23612.20377260761 19999.285827770796 23392.421704472483 24055.699271978712 19735.84684746076 1.0177367241588122 0.9163096318542492 1.1201361329453308 1.0218006111237667 0.9861754711948958 1.196411988556021 1.0133482481064109 1.1852758022127732 1.2188835603511865 1.0 14.268530804856965 -6.748180518895456 24.989791760747885 1.1275239343572623 1.0135956582696068 0.31037968145180295 0.08208390057145687 283.6425197728958 534597.678015093 0.02677941051796326 0.026630793598517204 1.7857451575237787e-07 6.748180518895456 -0.11392827608765543 AGGPATPLS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 2 AGGPATPLSPTR 12 0 Q03252 Q03252 LMNB2 Lamin-B2 1 AGGPATPLS(0.889)PT(0.111)R;AGGPATPLS(0.5)PT(0.5)R 116.98 0.00065179 85963000.0 93635.0 91176.0 112356.0 173308.0 120027.0 125394.0 83727.0 101674.0 114777.0 118014.0 True False 123408.98227100981 120646.85895614215 110866.08602789379 133354.51818190844 103363.32286683012 117553.09335734315 91178.54079930895 85962.61953608821 120843.87789811044 113882.36578066602 1.0836531312379984 1.0593989519721108 0.9735140754049535 1.1709847900310149 0.90763238152169 1.032232624880193 0.8006379229503894 0.7548369666085933 1.06112897347823 1.0 16.79718484334075 -6.679386674901888 1.7319139574905338 0.8940091974480258 1.0601485416635095 0.27014334746129554 0.10504550681456407 0.4268706372468818 2.6423720874286794 0.042127999010652305 0.04090697020250296 2.092248788703343e-07 6.679386674901888 0.1661393442154837 AGGPATPLS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AGGPATPLSPTR 12 0 Q03252 Q03252 LMNB2 Lamin-B2 1 AGGPAT(0.007)PLS(0.652)PT(0.341)R;AGGPATPLS(0.5)PT(0.5)R;AGGPATPLS(0.687)PT(0.313)R;AGGPAT(0.001)PLS(0.948)PT(0.051)R 97.95700000000001 0.0038085999999999997 99064100.0 142223.0 112374.0 148607.0 112093.0 147090.0 141445.0 137086.0 141470.0 157286.0 83330.0 True False 166298.54486770713 123529.74806610648 152150.35447518612 105812.7926204092 118268.77039439978 134027.37520030825 124100.22166330741 137756.56239985547 159586.01019412215 98437.06936008274 1.6893894337649078 1.2549108671067273 1.54566115655699 1.074928310120104 1.201465780759611 1.361553895007136 1.2607061797964432 1.3994378672118128 1.6211983070153848 1.0 16.58691408648599 -3.0129945203868176 1.7970225557802662 1.3089432970556554 198.07696101132197 0.27558936874321427 0.18373484994816666 997.1965790466653 8.008857866121105 0.04880237617975117 805044.9670054361 0.0009705222125144981 3.0129945203868176 196.7680177142663 AGGPATPLS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 3 AGGPATPLSPTR 12 0 Q03252 Q03252 LMNB2 Lamin-B2 1 AGGPAT(0.008)PLS(0.929)PT(0.064)R;AGGPAT(0.007)PLS(0.633)PT(0.36)R;AGGPAT(0.001)PLS(0.5)PT(0.5)R 84.352 0.010256 127880000.0 133907.0 129774.0 157823.0 117499.0 138806.0 127520.0 133726.0 114120.0 128613.0 110756.0 True False 131997.4616244638 129473.51627629089 144847.40215439803 126140.26842517359 130641.70398309575 122066.26686363902 140649.67795365682 119422.43181554224 114127.24958506889 129900.02702690645 1.0161465293392349 0.996716623080246 1.115068298826416 0.9710565217899909 1.0057095981668709 0.9396939296891385 1.0827532616642472 0.9193410852085968 0.8785775661265219 1.0 16.987042205388732 -7.790162397151486 24.994143235540744 0.9242193788815675 1.0157568995070518 0.33161747391628726 0.05517996096954409 235.5385079825192 204957.2285809318 0.029333049978312854 0.01409515245322691 1.6212037619934138e-08 7.790162397151486 0.09153752062548437 AGGPATPLSPT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 AGGPATPLSPTR 12 0 Q03252 Q03252 LMNB2 Lamin-B2 1 AGGPATPLS(0.331)PT(0.669)R 89.74700000000001 0.017907 37477000.0 51912.0 28025.0 64835.0 89943.0 50015.0 57794.0 45026.0 48543.0 54202.0 46895.0 True False 68418.93616332201 37083.53319125522 63975.245537563525 69208.03095549773 43071.28057174233 54180.13204375239 49033.22677308016 41041.79475716837 57067.007064423844 45253.22032372711 1.5119130898060902 0.8194672760517693 1.4137169704145918 1.5293504077810494 0.9517837683953567 1.19726577812949 1.0835301095107064 0.9069364448224558 1.2610595810902445 1.0 15.46573284091124 -6.283109111281489 24.983988452525654 1.0694729734549773 1.2897520093305253 0.2520862654703866 0.2101493374888135 1311.7188601669206 1512334.3517913977 0.06488659605204157 0.07363586410366785 5.210637836305852e-07 6.283109111281489 0.22027903587554798 AGGPS(ph)DDDNADKPK ddPTM_PC-9_Lapatinib_30min_R1 1 AGGPSDDDNADKPK 14 1 E7EVA0 E7EVA0 MAP4 Microtubule-associated protein 1 AGGPS(1)DDDNADKPK 126.48 0.0011025 0.0 10851.0 7943.8 7972.4 7867.1 9317.5 8278.4 6909.2 7195.9 7769.2 6981.3 True False 10696.26275017031 7925.406619165613 7316.9400463539605 8445.672777876263 8769.46296890981 7924.3521298929445 7266.924569024763 7530.247783924481 6894.150882697055 8188.008403002483 1.3063326542566893 0.9679284911651317 0.893616577588134 1.0314685039623672 1.0710129420109182 0.9677997065790922 0.8875081962983862 0.9196678133797707 0.8419814127412254 1.0 12.999296867600327 -6.9913395491630475 3.9633038570012347 0.9068252305691689 1.038744054626613 0.28000577670448046 0.10600225626295444 0.32403152650878514 11.588448673999812 0.04099056562123886 0.0339457883116714 1.0201415834790902e-07 6.9913395491630475 0.13191882405744404 AGGPT(ph)TPLSPTR ddPTM_PC-9_AZD4547_30min_R2 1 AGGPTTPLSPTR 12 0 P20700;E9PBF6;A0A0D9SFE5;A0A0D9SFY5 P20700 LMNB1 Lamin-B1 1 AGGPT(0.792)T(0.207)PLSPTR 105.36 0.0044020000000000005 61404000.0 77309.0 69877.0 78291.0 118360.0 107620.0 107140.0 77048.0 94366.0 78762.0 95731.0 True False 101891.65387290544 92463.37373078823 77252.8101855693 91073.9306437712 92678.82065642127 100440.51886299002 83905.12273824643 79783.9030149549 82925.19852419019 92379.48682824873 1.1029683901832197 1.0009080685054623 0.8362550262830227 0.9858674665848186 1.0032402629463515 1.0872599785028931 0.9082657375467156 0.863653888479469 0.8976581422060085 1.0 16.495284911529893 -7.462183915637082 24.845345360273665 0.9055853646675696 0.9946373257123824 0.22699309011283175 0.07504997281998796 340.59367757522614 139421.57074219352 0.03294067627858636 0.022208548619691723 3.44997608324499e-08 7.462183915637082 0.08905196104481283 AGGPTT(ph)PLSPTR ddPTM_PC-9_AZD4547_30min_R2 1 AGGPTTPLSPTR 12 0 P20700;E9PBF6;A0A0D9SFE5;A0A0D9SFY5 P20700 LMNB1 Lamin-B1 1 AGGPT(0.05)T(0.95)PLSPTR 100.02 0.0077343 58492000.0 43272.0 39731.0 64106.0 91480.0 73051.0 64102.0 57879.0 73220.0 51262.0 73060.0 True False 57031.59588648627 52573.26876794866 63255.912553883725 70390.69935191088 62909.1296020464 60093.69180656498 63030.11887351988 61905.531428215545 53971.604666552856 70502.19163773338 0.8089336595312657 0.7456969428424264 0.8972190946760386 0.9984185982983991 0.8923003404673862 0.8523662940203169 0.8940164469977359 0.8780653479016555 0.7655308780169436 1.0 16.105380485511148 -11.073191418944294 0.01444773761840524 1.8752541805601244 5.5566419093515625e-06 0.17875236219299606 0.07338230951076245 6550.133461927827 14.940193708079184 1074.1336561926048 872.2573712600353 8.449063634957215e-12 11.073191418944294 -1.8752486239182151 AGGPTT(ph)PLSPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGGPTTPLSPTR 12 0 P20700;E9PBF6;A0A0D9SFE5;A0A0D9SFY5 P20700 LMNB1 Lamin-B1 1 AGGPT(0.311)T(0.688)PLS(0.002)PTR;AGGPT(0.136)T(0.864)PLSPTR 87.641 0.020706 26456200.0 75598.0 81543.0 91070.0 98636.0 115857.0 113115.0 114484.0 97635.0 95496.0 88584.0 True False 88395.24827143933 89638.05014108715 93241.45418489828 93109.74470222661 93155.65253643335 107183.05027242294 103639.24672761705 95072.18470283334 96892.44833931753 104643.57796944187 0.844726929131309 0.8566034522181891 0.8910384755013513 0.8897798269991936 0.890218533655613 1.0242678275366564 0.9904023614127748 0.908533390654861 0.9259282816917075 1.0 16.675124249805563 -6.609654067026864 7.426066232925334 0.9652185266707718 0.873330507833758 0.6601528086723806 0.03432703591279671 0.16694729339771927 12.21840334938723 0.012443806965135935 0.012435084244933135 2.456664968721599e-07 6.609654067026864 -0.09188801883701381 AGGPTT(ph)PLSPTR ddPTM_PC-9_Lapatinib_30min_R1 1 AGGPTTPLSPTR 12 0 P20700;E9PBF6;A0A0D9SFE5;A0A0D9SFY5 P20700 LMNB1 Lamin-B1 1 AGGPT(0.189)T(0.811)PLSPTR 117.86 0.0014949000000000002 47175000.0 62720.0 53896.0 59073.0 54580.0 77481.0 68936.0 61902.0 66494.0 83295.0 65147.0 True False 61825.60129856069 53771.207123360364 54216.24596837428 58593.995273542554 72923.71991350695 65987.76797766476 65106.98267118779 69583.55398828139 73913.4399647648 76407.5721470791 0.8091554221818595 0.7037418623883853 0.7095664008799009 0.7668611058698909 0.9544043589440849 0.8636286446930028 0.8521011837133303 0.9106892423481018 0.9673575260641277 1.0 16.221427998932356 -6.639975933509384 0.42500675883223715 0.9878647134752053 0.69654994657249 0.6963436745835543 0.055269847321126636 0.8634261986819575 0.3156061194775877 0.05909659292761312 0.10380513137225414 2.2909946050427813e-07 6.639975933509384 -0.2913147669027153 AGGPTTPLS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 3 AGGPTTPLSPTR 12 0 P20700;E9PBF6;A0A0D9SFE5;A0A0D9SFY5 P20700 LMNB1 Lamin-B1 1 AGGPTT(0.002)PLS(0.658)PT(0.339)R;AGGPTTPLS(0.67)PT(0.33)R;AGGPTT(0.002)PLS(0.67)PT(0.328)R 91.307 0.006475700000000001 363954000.0 127496.0 109619.0 134065.0 195234.0 141375.0 132466.0 110296.0 129566.0 108884.0 108873.0 True False 168037.0759184562 145051.19803362028 132287.21050348514 150225.81763523142 121747.52156013343 124182.88007938034 120112.13032833568 109544.5518304857 114639.38594890828 105061.38940836198 1.5994179866146134 1.380632779087114 1.259142023996079 1.4298860740487669 1.1588226868665739 1.1820030248857194 1.1432566331430583 1.0426718364126917 1.0911657136316528 1.0 16.680873043418615 -1.5228787452803378 0.21182633099363338 0.9726444911372868 3.9835932350074437 0.8600934771425173 0.06713045787536367 17.981629160518096 0.22498391944052612 0.11212228611911589 18.288022712550642 0.02999999999999998 1.5228787452803378 3.010948743870157 AGGPTTPLS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 AGGPTTPLSPTR 12 0 P20700;E9PBF6;A0A0D9SFE5;A0A0D9SFY5 P20700 LMNB1 Lamin-B1 1 AGGPT(0.055)T(0.039)PLS(0.793)PT(0.113)R;AGGPTT(0.001)PLS(0.663)PT(0.336)R;AGGPTTPLS(0.657)PT(0.343)R;AGGPTTPLS(0.687)PT(0.313)R;AGGPTTPLS(0.675)PT(0.325)R 97.95700000000001 0.0038085999999999997 312507000.0 211283.0 216445.0 240943.0 247114.0 284892.0 272750.0 245829.0 264645.0 253290.0 217311.0 True False 247049.03887053274 237932.2291648289 246687.99490141653 233269.0037343974 229069.45771433436 258446.50985106672 222542.29747216497 257698.34916455514 256993.88707239818 256707.76406706995 0.9623746276952743 0.9268602764295997 0.960968188079284 0.9086947743171933 0.8923355261451519 1.006773249692372 0.866909102967456 1.0038588045869403 1.0011145864885236 1.0 17.96976740498851 -7.823100114178606 24.999372355290227 1.001865629531991 0.933475927241682 0.42435767725244367 0.03708508032810293 66.386222000809 26913.994363018468 0.019114067492099186 0.009182103919759198 1.502795499612174e-08 7.823100114178606 -0.06838970229030894 AGGPTTPLS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 2 AGGPTTPLSPTR 12 0 P20700;E9PBF6;A0A0D9SFE5;A0A0D9SFY5 P20700 LMNB1 Lamin-B1 1 AGGPTTPLS(0.714)PT(0.286)R;AGGPT(0.002)T(0.014)PLS(0.971)PT(0.013)R 126.5 0.00026178 169154000.0 92405.0 81612.0 108170.0 90279.0 91863.0 82244.0 72456.0 74699.0 105965.0 74494.0 True False 91087.2877549982 81423.03242822614 99276.68014827481 96918.4188219154 86459.79894960679 78726.615840128 76207.41715006929 78169.78824210665 94030.10583908159 87370.18864298456 1.0425442495861212 0.9319315168351081 1.136276362569652 1.109284760937706 0.9895800878135007 0.9010695417154669 0.8722359231873812 0.8946963427254009 1.076226425735568 1.0 16.414853484978558 -6.511230891504368 6.575407341350682 0.9380279096369808 1.0520056037485288 0.30616263245382846 0.07443942951152656 0.18632148011744906 38.090027049277325 0.024942205344496565 0.026686422903228736 3.081549217241657e-07 6.511230891504368 0.11397769411154801 AGGS(ph)PAPGPETPAISPSKR ddPTM_PC-9_AZD4547_30min_R2 1 AGGSPAPGPETPAISPSKR 19 1 P33316;H0YKI0 P33316 DUT Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial 1 AGGS(0.695)PAPGPET(0.157)PAIS(0.131)PS(0.016)KR 58.93 0.010589 2362600.0 8436.6 7797.0 10001.0 15699.0 10097.0 11437.0 10170.0 14188.0 8527.1 10003.0 True False 11119.263307818686 10317.227771354752 9868.38020546269 12079.838097132168 8695.205836906567 10721.84258200499 11075.110298099431 11995.570607805545 8977.825097580331 9652.798014676235 1.1519212658249784 1.0688328664567839 1.0223336477629266 1.251433841127291 0.9007964140227805 1.1107497086029736 1.1473471506666455 1.2427039900314218 0.9300748947538666 1.0 13.236731475415185 -4.752919292012934 23.77275267788365 1.084318196308278 1.1519215085841734 0.03469591442368236 0.11240447219813549 775.0257422031492 2162160.8865272254 0.026824741697421526 0.2917931807261869 1.7663660463678994e-05 4.752919292012934 0.06760331227589544 AGGS(ph)VESLR ddPTM_PC-9_AZD4547_30min_R2 1 AGGSVESLR 9 0 O94885 O94885 SASH1 SAM and SH3 domain-containing protein 1 1 AGGS(0.988)VES(0.012)LR 86.344 0.011734999999999999 10398000.0 22466.0 31759.0 37611.0 53285.0 47489.0 47593.0 38759.0 44834.0 38203.0 37316.0 True False 29609.720678170634 42024.47566890546 37112.25356540916 41000.96649504345 40895.972069808464 44617.002186356876 42208.47591386788 37905.93548282731 40222.33258702973 36009.578198106436 0.8222734661115153 1.1670360435134262 1.0306217240656463 1.138612795447837 1.1356970593995732 1.2390315138071533 1.172145801921318 1.0526625797805262 1.1169898288101807 1.0 15.136093080020045 -4.756277304403292 24.999233082621615 1.1227238674392046 0.8222729995130788 0.6244043932442367 0.06843958217580798 105.93444292141177 512969.3053763099 0.017135147560422285 0.14056761603160223 1.752760976807163e-05 4.756277304403292 -0.30045086792612585 AGGS(ph)VESLR ddPTM_PC-9_Lapatinib_30min_R1 2 AGGSVESLR 9 0 O94885 O94885 SASH1 SAM and SH3 domain-containing protein 1 1 AGGS(0.999)VES(0.001)LR;AGGS(1)VESLR 112.85 0.0021408 17672700.0 95506.0 96474.0 108920.0 87933.0 104755.0 105607.0 96538.0 97239.0 105003.0 84959.0 True False 94144.06692634443 96250.62038034468 99965.0180433587 94399.88615588914 98593.51685625418 101090.43479194102 101536.2652759381 101757.07892842204 93176.45640939074 99644.04994924835 0.9448036985077862 0.9659444836833505 1.0032211466141112 0.9473710292181999 0.9894571417608052 1.0145155164149726 1.0189897472819853 1.0212057717470326 0.9350930282023688 1.0 16.60449603945574 -6.510029321292042 21.47113619139076 1.0007544755923319 0.9681259109853301 0.2377320481407249 0.027318980044311474 140.70461011041877 235116.39933483148 0.00869864940525473 0.009393702126596648 3.090086798971347e-07 6.510029321292042 -0.03262856460700181 AGGSAALS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 3 AGGSAALSPSK 11 0 Q92522 Q92522 H1FX Histone H1x 1 AGGSAALS(0.858)PS(0.142)K;AGGSAALS(1)PSK;AGGSAALS(0.992)PS(0.008)K 185.57 0.00011162 1099182000.0 1010380.0 1170650.0 1151350.0 1465450.0 1145500.0 1133770.0 1213500.0 1304490.0 1157730.0 1267090.0 True False 1331659.8227904409 1549039.719191539 1136082.3467212743 1127613.143476802 986467.0977692844 1062875.1826702608 1321499.1491390066 1102911.0446980712 1218925.24424736 1222729.5647721784 1.0890877763625177 1.2668702580035835 0.9291362370328811 0.9222097640919489 0.806774552763092 0.8692643191859828 1.0807779473175911 0.9020073419943583 0.9968886656261335 1.0 20.22167392273576 -5.274256543133274 24.69945315913386 0.9322217875597248 1.177979011902997 0.5760630816340031 0.08207999947568848 387.1878299327727 746135.0771099158 0.0217714449070245 0.04581833121268978 5.317940291418422e-06 5.274256543133274 0.24575722434327207 AGGSAALS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AGGSAALSPSK 11 0 Q92522 Q92522 H1FX Histone H1x 1 AGGSAALS(0.982)PS(0.018)K;AGGSAALS(0.961)PS(0.039)K;AGGSAALS(0.979)PS(0.021)K 151.7 9.717299999999999e-05 766170000.0 1101350.0 969760.0 1115670.0 1128490.0 1384060.0 1034830.0 1232970.0 1260350.0 1021750.0 829640.0 True False 1287786.8023459637 1066031.3638794338 1142271.8040020394 1065264.3639139421 1112863.3785578446 980561.6930858988 1116174.1556702256 1227267.1479512097 1036691.1607889119 980047.164573375 1.3140049263920386 1.0877347564629594 1.165527380000413 1.0869521411019674 1.1355202267661126 1.000525003827492 1.1388984081762108 1.2522531489445736 1.057797214525073 1.0 19.90249165474505 -4.757418182388117 24.98861063217796 1.1111031540383816 1.3140052221395955 0.4281304863893718 0.07266113817724618 117.85812268675733 732295.5726029754 0.017714752307786488 0.13203801770847065 1.7481625712643314e-05 4.757418182388117 0.20290206810121392 AGGSAALS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 4 AGGSAALSPSK 11 0 Q92522 Q92522 H1FX Histone H1x 1 AGGSAALS(0.976)PS(0.024)K;AGGSAALS(0.988)PS(0.012)K;AGGS(0.001)AALS(0.98)PS(0.018)K;AGGSAALS(1)PSK 160.56 0.00012319999999999999 1460540000.0 1651090.0 1484410.0 1517270.0 1393370.0 1454260.0 1352810.0 1390830.0 1341580.0 1401720.0 1105390.0 True False 1627545.1538271795 1480972.9398468763 1392525.9174315745 1495843.077946058 1368723.285985166 1294953.469854134 1462840.3720165445 1403914.7044785814 1243843.5328340272 1296455.1886604107 1.255380955749712 1.142324819862939 1.0741026219891416 1.1537946633478855 1.055742842449825 0.998841673187464 1.1283385533194208 1.0828871809516267 0.9594188397049453 1.0 20.306140910328594 -1.5228787452803376 0.3686913516295777 1.0296328607632566 3.7842022588593807 0.6285783726511645 0.05110786129194386 47.0326491327902 0.6507176880475586 0.04170515490440455 91.643278716204 0.029999999999999995 1.5228787452803376 2.754569398096124 AGGSAALS(ph)PSKK ddPTM_PC-9_AZD4547_30min_R2 1 AGGSAALSPSKK 12 1 Q92522 Q92522 H1FX Histone H1x 1 AGGSAALS(0.877)PS(0.123)KK 131.53 0.00016706 49749000.0 28320.0 37406.0 30336.0 41446.0 33655.0 35106.0 35606.0 33788.0 31157.0 34377.0 True False 37325.170907406435 49496.75798580171 29933.724818809704 31891.265034316817 28982.584177586486 32910.81627033901 38774.86502203819 28566.840970999016 32803.89541172381 33173.47169354445 1.1251511826140856 1.4920584267770132 0.9023392274205294 0.961348433137399 0.8736675029169916 0.9920823655229141 1.1688515866002582 0.8611351032203878 0.9888592823435913 1.0 15.01774238151468 -5.2739772192094385 24.999764898875195 0.9679262590990635 1.308604812267965 0.5793155962859201 0.11591631421073509 438.16592382099446 873679.1649133012 0.029252022809814985 0.06155899485676536 5.321361715826192e-06 5.2739772192094385 0.3406785531689015 AGGSAALS(ph)PSKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AGGSAALSPSKK 12 1 Q92522 Q92522 H1FX Histone H1x 1 AGGS(0.002)AALS(0.966)PS(0.032)KK;AGGS(0.003)AALS(0.747)PS(0.25)KK;AGGS(0.003)AALS(0.961)PS(0.036)KK;AGGS(0.022)AALS(0.852)PS(0.126)KK 162.48 0.001003 233955000.0 313931.0 267237.4 272669.3 331099.0 412951.0 309335.0 352171.0 402826.0 338252.0 250953.4 True False 367073.31788011966 293766.96296155086 279170.77021607937 312548.5964674407 332036.2159435566 293112.9280468551 318810.8133827571 392252.24432942783 343198.2955900851 296449.2648739787 1.2382331864987537 0.9909519022974536 0.9417151711769485 1.054307207003215 1.1200439848778376 0.988745673467796 1.0754312833876796 1.3231682139477567 1.1576965648269681 1.0 18.177425693616946 -7.5473902053845565 24.973285053360684 1.184119474116222 1.0488827508954084 0.1507419775234642 0.10645984115429966 318.1476977662968 324137.7983636657 0.04859260456761228 0.028056175825779125 2.8353703569644204e-08 7.5473902053845565 -0.1352367232208136 AGGSAALS(ph)PSKK ddPTM_PC-9_Lapatinib_30min_R1 3 AGGSAALSPSKK 12 1 Q92522 Q92522 H1FX Histone H1x 1 AGGSAALS(0.5)PS(0.5)KK;AGGSAALS(0.968)PS(0.032)KK;AGGS(0.004)AALS(0.974)PS(0.023)KK 156.52 0.0005502999999999999 111116300.0 241250.0 196874.6 219732.0 185624.7 212879.0 180570.3 185099.0 185298.3 178879.0 157499.9 True False 237809.73076016817 196418.74895963928 201666.48315004905 199276.1596638465 200357.8757562169 172847.72919892834 194682.5205236374 193907.93548270172 158731.7633406229 184723.54785957516 1.2873817849197469 1.0633119125069788 1.0917204952308177 1.0787804910250753 1.0846363556666136 0.9357103152345543 1.0539128485753908 1.0497196363406165 0.859293604848306 1.0 17.49500826179022 -1.5228787452803376 0.39801983654864453 0.9830825739004698 5.142405270095625 0.6135364513673482 0.06586107375562206 51.56921093061269 0.6861840272944904 0.04721735731513275 167.93036769154654 0.029999999999999995 1.5228787452803376 4.159322696195155 AGGSAALSPS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGGSAALSPSK 11 0 Q92522 Q92522 H1FX Histone H1x 1 AGGSAALS(0.401)PS(0.599)K 103.46 0.0028951999999999997 143110000.0 304450.0 272440.0 290740.0 331520.0 415370.0 289080.0 349950.0 368810.0 305430.0 202600.0 True False 355987.37183840555 299486.0427067657 297672.3442375902 312946.0092023421 333981.23025849473 273920.13590374455 316800.20258140547 359129.1282864961 309896.33593320975 239329.77621928297 1.487434524286842 1.251353038630535 1.2437747986897025 1.3075932888334343 1.3954854909173044 1.1445301133477372 1.3236974002396642 1.5005618354711052 1.294850732026219 1.0 17.868640375414664 -11.725155507863187 2.1457980386108733 0.11986720433095747 1.3239658840861608 0.47184843058083625 0.10394201881875796 1283884.2834623836 194627.7725834696 5512539.182105686 0.026038700132697223 1.8829747318361428e-12 11.725155507863187 1.2040986797552033 AGGSAALSPS(ph)KK ddPTM_PC-9_AZD4547_30min_R2 1 AGGSAALSPSKK 12 1 Q92522 Q92522 H1FX Histone H1x 1 AGGSAALS(0.261)PS(0.739)KK 156.52 0.0005502999999999999 46208000.0 137820.0 106420.0 119380.0 173650.0 121110.0 116730.0 118820.0 153860.0 98708.0 133480.0 True False 181643.89316591667 140818.18384347472 117796.94319849362 133617.6753657557 104295.96701077092 109430.85464697384 129394.74981515983 130084.47235106876 103925.5033636242 128806.90582815021 1.410203063244604 1.0932502643247215 0.9145235066484269 1.0373486926549098 0.8097078828204992 0.849572885424115 1.0045637614165959 1.0099184629481206 0.8068317664759223 1.0 16.97485041833145 -4.669303999226639 1.6180242503145892 0.925234348714858 1.6948125760069868 0.7673790439374027 0.08092507579402204 0.6396917540007867 1.314048567290505 0.02268189046879854 0.8465268687084657 2.1413911366597884e-05 4.669303999226639 0.7695782272921288 AGGSPAPGPETPAIS(ph)PSKR ddPTM_PC-9_AZD4547_30min_R2 1 AGGSPAPGPETPAISPSKR 19 1 P33316;H0YKI0 P33316 DUT Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial 1 AGGSPAPGPET(0.004)PAIS(0.987)PS(0.009)KR 183.39 1.3757e-10 5209900.0 18270.0 17867.0 28588.0 56028.0 38436.0 28581.0 20532.0 34323.0 23062.0 26533.0 True False 24079.47996039248 23642.1583417719 28208.904440932627 43111.61022397099 33099.82485365365 26793.825551830432 22359.30822424559 29019.169014075957 24281.01023799387 25604.08774601666 0.9404545164526954 0.9233743680420723 1.1017344074412965 1.6837784127137296 1.2927554842801667 1.0464667133473196 0.873271035704997 1.1333803141879404 0.9483255360961405 1.0 14.644086537435577 -6.92401135442973 6.608718264423513 0.994358404288734 1.1954578261775684 0.1734638983860941 0.2078491907234574 0.43872648795557334 30.641615465151062 0.08293401583835208 0.07300566450515943 1.191210863959414e-07 6.92401135442973 0.20109942188883434 AGGSPAPGPETPAIS(ph)PSKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGGSPAPGPETPAISPSKR 19 1 P33316;H0YKI0 P33316 DUT Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial 1 AGGSPAPGPET(0.028)PAIS(0.907)PS(0.065)KR 152.66 5.5833999999999994e-05 3778600.0 6345.6 7614.3 5417.8 9911.8 8959.4 8954.7 6212.2 10161.0 6948.1 8029.2 True False 7419.784748687088 8370.197382844384 5546.98089912092 9356.473980489167 7203.869885591046 8485.099768151584 5623.735443566804 9894.284516469419 7049.702817986221 9484.830400887777 0.7822791167665579 0.8824825567846671 0.5848265772471508 0.9864671886608963 0.7595148865199284 0.8945968888760922 0.5929189248381737 1.0431693660588088 0.7432608196480109 1.0 13.211406261568664 -14.522878580069417 0.21987654028522455 1.973892556069744 0.7863038832269459 0.1407056538900081 0.14262985599739045 295.54415001257155 2.949105243700431 127.17337195184781 0.2544278756284934 3.0000011412368262e-15 14.522878580069417 -1.1875886728427982 AGGTSSPSPVVFTVGS(ph)PPSGSTPPQGPR ddPTM_PC-9_Lapatinib_30min_R1 1 AGGTSSPSPVVFTVGSPPSGSTPPQGPR 28 0 O75385 O75385 ULK1 Serine/threonine-protein kinase ULK1 1 AGGTSS(0.001)PS(0.002)PVVFT(0.09)VGS(0.588)PPS(0.022)GS(0.173)T(0.123)PPQGPR 52.858000000000004 0.034944 0.0 5924.0 4767.4 7432.8 6392.1 5797.1 5284.3 5168.8 3946.1 6663.3 6472.1 True False 5839.5226736714485 4756.361378208183 6821.70387543772 6862.196357420512 5456.125975537114 5058.302807304948 5436.415172867363 4129.450211946304 5912.808986340327 7590.793861468835 0.7692901138197275 0.6265960405474398 0.8986812183195956 0.9040156382395375 0.7187819976554259 0.6663733595745618 0.7161853255511019 0.5440076871152508 0.7789447446799965 1.0 12.890035058328282 -4.4255816002436665 21.806711531732265 0.7471967624138909 3.6977623912256914 0.0 0.1328867854745166 7991.2360175496015 1773172.2166789921 0.03234223328532261 11722.651578279141 3.753344256964211e-05 4.4255816002436665 2.9505656288118005 AGIIASAR ddPTM_PC-9_Lapatinib_30min_R1 2 AGIIASAR 8 0 P13639 P13639 EEF2 Elongation factor 2 0 ; 106.42 0.01763 17763400.0 92942.0 83345.0 74101.0 78405.0 88467.0 100090.0 74848.0 67161.0 90176.0 83005.0 False True 91616.63003652474 83152.0197732015 68008.70181813187 84171.16525141269 83263.54499281397 95809.38402118589 78723.26320592334 70281.54524328478 80019.42928462253 97352.30365278972 0.9410833292993102 0.8541351016177899 0.6985833849467723 0.8646037339970094 0.8552806853937038 0.9841511749212766 0.8086430444079938 0.7219299657658466 0.821957224248278 1.0 16.57092749746917 -4.789864595289213 4.938980338626899 0.8355979377251571 0.9455374072899771 0.083841229821225 0.09111808334045275 0.38435362663853573 22.04324443814392 0.02306892382243523 0.1349124462941504 1.622315825553846e-05 4.789864595289213 0.10993946956482004 AGIPVYAWK ddPTM_PC-9_Lapatinib_30min_R1 1 AGIPVYAWK 9 0 P23526;P23526-2 P23526 AHCY Adenosylhomocysteinase 0 97.473 0.021988 2948200.0 39585.0 41915.0 43536.0 40966.0 40843.0 39703.0 47882.0 34220.0 42884.0 38214.0 False True 39020.510641000066 41817.948392749946 39956.63813381991 43978.776298569865 38440.69504042754 38004.9952422134 50361.09567157465 35809.986126251846 38053.952331460205 44819.238983045696 0.8706196608059502 0.9330356637373721 0.8915063941387935 0.9812477252281377 0.8576829038745829 0.8479616366665663 1.1236490581784608 0.7989869292470163 0.8490539597482974 1.0 15.451830532085683 AGKSKKS(ph)FS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGKSKKSFSR 10 3 A1L167 A1L167 UBE2QL1 Ubiquitin-conjugating enzyme E2Q-like protein 1 2 AGKSKKS(1)FS(1)R 50.473 0.044913999999999996 5172600.0 39587.0 37986.0 46874.0 52243.0 48548.0 42388.0 50604.0 37585.0 38687.0 42998.0 True False 46288.29722111001 41756.99903927172 47991.65393063491 49315.99408409128 39035.36790473399 40165.098660190655 45810.422778766726 36598.43357459925 39252.72418638664 50793.197028019276 0.9113089927293964 0.8220982628094294 0.944844127534659 0.9709173072308657 0.7685156711675529 0.7907574441127264 0.9019007555971742 0.7205380979348532 0.7727949111912267 1.0 15.632347662547495 -6.267935250310092 24.979122880722386 0.8138358477310994 0.9081748903153197 0.2003076555532871 0.08251553647471369 766.3661380456508 2946968.00970761 0.024915695805099433 0.028924279154110295 5.39591065051737e-07 6.267935250310092 0.09433904258422032 AGLAS(ph)PEEEDAVGKEPLK ddPTM_PC-9_AZD4547_30min_R2 2 AGLASPEEEDAVGKEPLK 18 1 Q9UNS1-2;Q9UNS1 Q9UNS1-2 TIMELESS Protein timeless homolog 1 AGLAS(1)PEEEDAVGKEPLK;AGLAS(1)PEEEDAVGKEPLK 100.01 0.00028978 44095000.0 201993.0 187857.0 233521.0 274960.0 265940.0 254580.0 237604.0 228695.0 225800.0 275040.0 True False 266222.57228459616 248578.10150614238 230424.358960089 211572.22008965255 229018.8214585458 238661.07235523596 258750.2957000611 193355.44263829192 237735.32702016382 265410.9333156609 1.0030580464745584 0.9365782275837945 0.8681796039126943 0.7971496028689352 0.8628839008156725 0.899213417374142 0.9749044339191629 0.7285134799188121 0.8957254475173346 1.0 18.01786827662719 -4.989127797575255 2.630721497161472 0.8695484083644165 1.0054069083670754 0.21296127786861507 0.07414503482698702 0.4630676283638449 5.635909252570833 0.0191855349048437 0.1138526824087949 1.0253501574031217e-05 4.989127797575255 0.13585850000265887 AGLAS(ph)PEEEDAVGKEPLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AGLASPEEEDAVGKEPLK 18 1 Q9UNS1-2;Q9UNS1 Q9UNS1-2 TIMELESS Protein timeless homolog 1 AGLAS(1)PEEEDAVGKEPLK;AGLAS(1)PEEEDAVGKEPLK;AGLAS(1)PEEEDAVGKEPLK 94.057 0.00046309 34202100.0 129320.0 138851.0 125047.0 191194.0 172718.0 150851.0 153504.0 142954.0 144383.0 116018.4 True False 151211.32181357403 152635.20964570914 128028.5947233882 180482.02003931173 138875.14776653715 142940.10800199176 138962.98984728078 139201.60897228343 146494.32822919983 137051.61751885075 1.1033165791916004 1.1137060066052482 0.9341633250390389 1.316890842346223 1.0133054266757238 1.0429654942403805 1.0139463682591499 1.0156874577064876 1.0688989366291155 1.0 17.06435982976324 AGLAS(ph)PEEEDAVGKEPLK ddPTM_PC-9_Lapatinib_30min_R1 1 AGLASPEEEDAVGKEPLK 18 1 Q9UNS1-2;Q9UNS1 Q9UNS1-2 TIMELESS Protein timeless homolog 1 AGLAS(1)PEEEDAVGKEPLK 69.122 0.0053369 21626000.0 25127.0 29367.0 30713.0 26982.0 34620.0 36563.0 27754.0 28540.0 27884.0 34853.0 True False 24768.684372272535 29299.002515803106 28187.895695608477 28966.34628931339 32583.71966553881 34999.28572251592 29190.966318635037 29866.072590392414 24743.41028846272 40877.29461129669 0.6059276820493781 0.7167549319104437 0.6895734163341275 0.7086170101215153 0.7971104735618707 0.8562035735320813 0.7141119928853593 0.7306274271423712 0.6053093905491663 1.0 15.319012096861647 -3.318635377238841 0.5176982855225333 0.7708011487528299 3.1517155168367655e-18 0.21858162752381705 0.09893028575321072 31.52621325705126 1.9666735288021553 0.053170359239618444 20.505873473936056 0.00048013638994140375 3.318635377238841 -0.7708011487528299 AGLES(ph)GAEPGDGDSDTTK ddPTM_PC-9_AZD4547_30min_R2 2 AGLESGAEPGDGDSDTTK 18 0 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 AGLES(0.962)GAEPGDGDS(0.037)DTTK;AGLES(1)GAEPGDGDSDTTK 239.7 1.1494e-43 14725000.0 52713.0 60661.0 74402.0 86728.0 80121.0 83358.0 82002.0 86938.0 68173.0 71860.0 True False 69474.63750148712 80268.48195949095 73415.38086659677 66734.19953424283 68997.58213912944 78145.61108251926 89300.0191410766 73503.72973649538 71776.4856020621 69344.20327248178 1.0018809680240006 1.1575370134989251 1.0587097032194264 0.9623616161832131 0.9950014403945154 1.1269234830697115 1.287779149905007 1.0599837660210634 1.0350754960731594 1.0 16.081487667151293 -6.778232283355966 24.57098539239051 1.1173155623603692 1.0391711398023795 0.11456374070238906 0.08751966525743883 407.29124898129203 595934.9792680605 0.03247705363503284 0.028720518365562633 1.6663557201530768e-07 6.778232283355966 -0.0781444225579897 AGLES(ph)GAEPGDGDSDTTK ddPTM_PC-9_Lapatinib_30min_R1 1 AGLESGAEPGDGDSDTTK 18 0 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 AGLES(0.999)GAEPGDGDS(0.001)DTTK 163.0 7.9397e-07 13162000.0 41907.0 50694.0 63049.0 53120.0 55919.0 68235.0 44339.0 51246.0 57074.0 44345.0 True False 41309.39849519741 50576.621157630085 57865.35459617811 57026.62200312533 52629.954360983924 65316.74811355394 46634.65646760682 53627.07624272073 50645.72510413578 52009.97416400174 0.7942591620010717 0.9724408052607006 1.1125818754247552 1.096455495695974 1.011920409631953 1.2558504241434978 0.8966483298098733 1.031092153086249 0.973769472456108 1.0 15.66650070082377 -4.833685212688753 3.124984303902812 1.050840254420522 0.7703688574988803 0.4140267681762245 0.09086516958418953 0.30029774914195295 4.6683133707651345 0.02298152010309624 0.1959935498441318 1.4666104911109944e-05 4.833685212688753 -0.2804713969216417 AGLESGAEPGDGDS(ph)DTTK ddPTM_PC-9_AZD4547_30min_R2 2 AGLESGAEPGDGDSDTTK 18 0 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 AGLESGAEPGDGDS(0.964)DT(0.029)T(0.008)K;AGLESGAEPGDGDS(0.999)DT(0.001)TK 216.17 1.6674e-27 34733000.0 54876.0 57611.0 50720.0 55066.0 57656.0 62615.0 58803.0 59922.0 57313.0 58645.0 True False 72325.42650829212 76232.62910549165 50047.41966014071 42371.38446121914 49651.45961500301 58699.6741516344 64036.353083494745 50662.431770575415 60342.44817319149 56591.85640014872 1.278018271690802 1.347060053419476 0.8843572705278703 0.7487187584309002 0.8773605033192113 1.0372459552586817 1.1315471369362335 0.8952247724893909 1.0662744078675057 1.0 15.788306842917484 -5.258402239004682 24.990150604903494 0.9504386942864427 1.3125391976000733 0.6457762267656757 0.1058489936941528 167.02754086060892 1374315.905556328 0.030059029555133048 0.07280942220334483 5.51566347653827e-06 5.258402239004682 0.36210050331363064 AGLESGAEPGDGDS(ph)DTTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGLESGAEPGDGDSDTTK 18 0 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 AGLESGAEPGDGDS(0.91)DT(0.045)T(0.045)K 66.436 0.013963999999999999 8463700.0 7498.6 9345.2 7887.4 9805.4 10648.0 7964.2 10340.0 6908.6 7352.0 8188.0 True False 8767.964875899046 10272.929695724804 8075.465529131071 9256.035227535713 8561.600837307564 7546.543331827186 9360.520344882772 6727.256570266772 7459.509091382496 9672.419583827665 0.9064913696009558 1.0620847872337131 0.8348961145806052 0.9569513757459251 0.8851560628762015 0.7802125689879134 0.9677537521773364 0.695509175544326 0.7712143819582469 1.0 13.239661113862208 -6.1329322539752456 0.8955259893846218 0.8266428212646035 0.9692624791474785 0.15286261614423646 0.10057469837137581 0.9925580301880067 1.6622686221553624 0.046890906984331175 0.08969764074722059 7.363219481238952e-07 6.1329322539752456 0.142619657882875 AGLESGAEPGDGDS(ph)DTTK ddPTM_PC-9_Lapatinib_30min_R1 3 AGLESGAEPGDGDSDTTK 18 0 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 AGLESGAEPGDGDS(1)DTTK;AGLESGAEPGDGDS(0.997)DT(0.002)TK;AGLESGAEPGDGDS(1)DTTK 223.93 8.240299999999999e-35 71197300.0 86967.0 120041.0 96066.0 106776.0 120458.0 115633.0 112890.0 108394.0 98678.0 106539.0 True False 85726.8346322055 119763.05243979733 88167.82430548368 114628.66323429423 113372.89726953999 110687.64614368838 118734.89182498788 113430.38095175146 87563.84451459357 124954.12419570584 0.6860664678657448 0.9584561791031552 0.705601554754554 0.9173659850935401 0.9073161690283461 0.8858262730914508 0.9502278743438891 0.9077762073230521 0.7007679424606201 1.0 16.931038993776596 -4.745586933131471 24.81367894569073 0.8773165133417343 0.6860658828346811 0.2729935485084226 0.09545184037020062 1134.7650660089112 1776129.7953535842 0.02275722352119094 0.5622376778189496 1.796441448820629e-05 4.745586933131471 -0.19125063050705327 AGLESGAEPGDGDS(ph)DTTKK ddPTM_PC-9_Lapatinib_30min_R1 2 AGLESGAEPGDGDSDTTKK 19 1 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 AGLESGAEPGDGDS(0.359)DT(0.32)T(0.32)KK;AGLESGAEPGDGDS(0.906)DT(0.076)T(0.018)KK 112.64 4.7641999999999995e-05 40170000.0 96227.0 106822.0 90891.0 103946.0 99828.0 87512.0 85600.0 96068.0 82828.0 77999.0 True False 94854.78533412924 106574.66022212387 83418.29282940616 111590.53559369077 93956.31330939935 83769.31576043571 90031.94915598315 100531.6699934762 73499.03842249291 91481.02322286564 1.036879365713307 1.1649920001713052 0.9118644489380372 1.2198216817255578 1.0270579623984246 0.9157015609276395 0.9841598397587633 1.0989346910622262 0.8034348090251997 1.0 16.481184882053498 -6.523762302562807 24.637566944354628 0.968474799338688 1.0827755324829913 0.24105143170699406 0.10253833741482354 38.10085026287355 1062368.5265567652 0.03197035204182747 0.032254168171107225 2.9939028068863026e-07 6.523762302562807 0.11430073314430333 AGLESGAEPGDGDS(ph)DTTKKK ddPTM_PC-9_Lapatinib_30min_R1 2 AGLESGAEPGDGDSDTTKKK 20 2 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 AGLESGAEPGDGDS(0.704)DT(0.148)T(0.148)KKK;AGLESGAEPGDGDS(0.572)DT(0.091)T(0.337)KKK 57.39 0.006100199999999999 19972500.0 220916.0 109314.0 99964.0 114876.0 107732.0 100497.0 86102.0 70978.0 100941.0 71810.0 True False 217765.69732896774 109060.8901492323 91745.3457921991 123324.36425510209 101395.41556926127 96198.97757994919 90559.94025967832 74275.89699792808 89571.96162414712 84222.26281918965 2.58560729716408 1.2949175965904265 1.0893241611088056 1.4642727484045133 1.2039027707785452 1.1422036687196524 1.0752494320188777 0.8819033651160066 1.0635188206287254 1.0 16.361914016801506 -4.757142520366422 3.7690585255093914 1.1282467462544619 2.777235565405613 0.9036642188060651 0.14309810106746756 0.08750130944503295 2.1421214843823693 0.039798022147362964 0.4182612942275018 1.7492725439239046e-05 4.757142520366422 1.6489888191511513 up AGLGS(ph)PERPPK ddPTM_PC-9_AZD4547_30min_R2 2 AGLGSPERPPK 11 1 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 AGLGS(1)PERPPK;AGLGS(1)PERPPK 128.68 0.001438 800590000.0 301560.0 227990.0 385940.0 483590.0 420800.0 351170.0 401370.0 422930.0 397000.0 436850.0 True False 397449.8071623406 301683.3089125527 380822.18343128357 372105.7968910208 362379.1835367215 329211.2843860005 437091.15244328114 357575.88646456227 417984.60950843693 421556.01446679095 0.9428161229417132 0.7156422837286278 0.9033726725805823 0.8826959742507345 0.8596228522443932 0.7809431560415677 1.036851894987526 0.8482286438656211 0.9915280417410925 1.0 18.685364817168264 -7.790177457543997 0.6988057205819918 0.9974848786688522 0.8444841864791711 0.28385725307303145 0.08098242418662248 0.8805191000827801 0.8477270998534764 0.07251488466113014 0.03553970771290994 1.6211475431311633e-08 7.790177457543997 -0.15300069218968104 AGLGS(ph)PERPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AGLGSPERPPK 11 1 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 AGLGS(1)PERPPK;AGLGS(1)PERPPK;AGLGS(1)PERPPK 130.1 0.001092 388229000.0 222219.0 210881.0 264402.0 279762.0 292486.0 242112.0 265070.0 288602.0 246878.0 207482.0 True False 259836.28767468702 231815.8720160232 270706.34643016895 264087.842140642 235175.46792831927 229415.22050618296 239960.650659388 281026.5032990949 250488.1237027106 245096.84417339117 1.0601372227007075 0.9458133693962518 1.10448727866386 1.0774836494990356 0.959520587551698 0.9360186634793453 0.9790442282872902 1.1465937239905288 1.0219965277296896 1.0 17.902992382857356 -11.076756282048956 3.732455420093071 0.9994644149064824 1.0247719780817603 0.012662787597515268 0.06759613501095339 0.00032295323463567293 3.860100309858821e-05 0.07016176262509688 0.016656739708724312 8.37999419819684e-12 11.076756282048956 0.025307563175277936 AGLGS(ph)PERPPK ddPTM_PC-9_Lapatinib_30min_R1 2 AGLGSPERPPK 11 1 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 AGLGS(1)PERPPK;AGLGS(1)PERPPK 95.273 0.030344 913000000.0 696140.0 663100.0 716400.0 725930.0 683500.0 633990.0 566740.0 564090.0 697710.0 630600.0 True False 686212.9159435583 661564.632690743 657500.3573839704 779317.313831492 643297.8738127023 606875.725602873 596083.024119883 590299.6807117875 619126.5525879841 739598.369778318 0.9278183186764446 0.8944917400088858 0.8889964935712946 1.053703395891853 0.8697935259180193 0.8205476788500409 0.8059550270487328 0.7981354540961466 0.8371118405433435 1.0 19.496382519196054 -6.50951336823112 24.378415165403503 0.8377600777926473 0.937625941261653 0.2643215245319903 0.0685534089140474 542.4521239989527 989433.5922865943 0.021129188346914966 0.022915779642275674 3.093760083441834e-07 6.50951336823112 0.09986586346900572 AGLLNTS(ph)GTK ddPTM_PC-9_AZD4547_30min_R2 1 AGLLNTSGTK 10 0 A0A087WT26;H3BQD9;Q08AM6 A0A087WT26 VAC14 Protein VAC14 homolog 1 AGLLNT(0.012)S(0.98)GT(0.008)K 78.653 0.020102000000000002 4435100.0 40370.0 45226.0 44410.0 53717.0 54861.0 61724.0 47423.0 61887.0 48308.0 57286.0 True False 53206.82025183609 59844.42005736698 43821.09438302147 41333.37556937694 47244.49711979116 57864.38852248629 51643.5551294759 52323.786171783344 50861.46225726339 55280.43457650134 0.9624891819221207 1.0825605933786508 0.7927053164239953 0.7477035208935744 0.854633243781949 1.0467426489277878 0.9342103680101782 0.94651546379169 0.9200626342196598 1.0 15.754481336789713 -6.733830678265522 24.980993324491898 0.9639575383591106 0.8857358278139555 0.16258875343109502 0.09196432764017522 486.05417105237643 439792.0480064512 0.03389980413543419 0.0338924559826596 1.8457348897944184e-07 6.733830678265522 -0.07822171054515503 AGLLNTS(ph)GTK ddPTM_PC-9_Lapatinib_30min_R1 1 AGLLNTSGTK 10 0 A0A087WT26;H3BQD9;Q08AM6 A0A087WT26 VAC14 Protein VAC14 homolog 1 AGLLNT(0.12)S(0.558)GT(0.322)K 81.625 0.016028999999999998 3367400.0 46963.0 41050.0 46516.0 34489.0 38901.0 39981.0 30185.0 24818.0 38358.0 27424.0 True False 46293.29900804058 40954.95124710446 42691.634036952564 37025.436111931296 36612.91966230862 38271.10583026306 31747.831603660703 25971.134882563376 34037.71811235308 32164.201859816963 1.4392802038055614 1.2733084882877153 1.3273027642040645 1.1511380345547302 1.1383127062154612 1.1898664856371117 0.9870548550226445 0.8074546663944848 1.0582484919321664 1.0 14.973168268850493 -6.234557780942197 0.5646088387957079 0.9350148741479457 1.4219681424656991 0.7565435482503391 0.0862018220220619 0.5418342894975948 0.34848802598530115 0.06620441875975877 0.14086892313922006 5.826962445046838e-07 6.234557780942197 0.48695326831775343 AGLQFPVGR ddPTM_PC-9_AZD4547_30min_R2 2 AGLQFPVGR 9 0 Q71UI9;P0C0S5;C9J0D1;A0A494C189;Q71UI9-2;A0A3B3IS11;Q71UI9-5;Q8IUE6;Q96QV6;Q9BTM1-2;A0A0U1RR32;A0A0U1RRH7;Q99878;Q96KK5;Q93077;Q7L7L0;Q6FI13;P20671;P0C0S8;P04908;Q9BTM1;Q16777;P16104 Q71UI9;A0A0U1RR32;P16104 H2AFV;H2AFZ;HIST2H2AB;HIST1H2AA;H2AFJ;HIST1H2AJ;HIST1H2AH;HIST1H2AC;HIST3H2A;HIST2H2AA3;HIST1H2AD;HIST1H2AG;HIST1H2AB;HIST2H2AC;H2AFX Histone H2A.V;Histone H2A.Z;Histone H2A;Histone H2A type 2-B;Histone H2A type 1-A;Histone H2A.J;Histone H2A type 1-J;Histone H2A type 1-H;Histone H2A type 1-C;Histone H2A type 3;Histone H2A type 2-A;Histone H2A type 1-D;Histone H2A type 1;Histone H2A type 1-B/E;Histone H2A type 2-C;Histone H2AX 0 ; 120.62 0.0076760000000000005 71517000.0 440000.0 433530.0 509320.0 750370.0 584720.0 496750.0 409610.0 557350.0 427220.0 503000.0 False True 579910.8474314566 573660.0943587829 502566.08401622385 577383.7896009333 503541.72100188216 465688.1439722814 446064.49648028647 471224.3641288702 449801.97701308405 485390.12310128537 1.1947314537969034 1.1818536617381445 1.0353858887881706 1.1895252130634142 1.0373958946354769 0.9594100122945997 0.9189814033096984 0.9708157247166332 0.9266813550699811 1.0 18.888785226729382 -6.524972113539305 2.891271484755067 0.9508098078942543 1.1445178878458304 0.785616920162569 0.04784901458851488 0.12103160505789172 2.0593685264505743 0.01651726839880092 0.017591238484842477 2.985574319322697e-07 6.524972113539305 0.19370807995157613 AGLQFPVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGLQFPVGR 9 0 Q71UI9;P0C0S5;C9J0D1;A0A494C189;Q71UI9-2;A0A3B3IS11;Q71UI9-5;Q8IUE6;Q96QV6;Q9BTM1-2;A0A0U1RR32;A0A0U1RRH7;Q99878;Q96KK5;Q93077;Q7L7L0;Q6FI13;P20671;P0C0S8;P04908;Q9BTM1;Q16777;P16104 Q71UI9;A0A0U1RR32;P16104 H2AFV;H2AFZ;HIST2H2AB;HIST1H2AA;H2AFJ;HIST1H2AJ;HIST1H2AH;HIST1H2AC;HIST3H2A;HIST2H2AA3;HIST1H2AD;HIST1H2AG;HIST1H2AB;HIST2H2AC;H2AFX Histone H2A.V;Histone H2A.Z;Histone H2A;Histone H2A type 2-B;Histone H2A type 1-A;Histone H2A.J;Histone H2A type 1-J;Histone H2A type 1-H;Histone H2A type 1-C;Histone H2A type 3;Histone H2A type 2-A;Histone H2A type 1-D;Histone H2A type 1;Histone H2A type 1-B/E;Histone H2A type 2-C;Histone H2AX 0 ; 92.47 0.032269 71838000.0 389720.0 400170.0 372690.0 448320.0 406590.0 383160.0 348240.0 345890.0 337150.0 297800.0 False True 455691.8986791378 439896.232968603 381576.3430346949 423202.08387305145 326921.60823073704 363066.4150853701 315252.18616073247 336810.754000748 342080.1809248645 351788.78261649737 1.2953565355036076 1.2504555423762787 1.0846745601057737 1.2030005070809928 0.9293122020525899 1.0320579649669133 0.896140530166946 0.9574232341794773 0.9724021851423935 1.0 18.424349955195623 -5.657417293994932 0.7668103261539864 0.9501153772943757 1.3286702508705106 0.7872255886060978 0.06174641063447136 0.44113380683398024 0.4246189124791312 0.027966809238756482 0.11784596002454599 2.2008107868880316e-06 5.657417293994932 0.37855487357613493 AGLQFPVGR ddPTM_PC-9_Lapatinib_30min_R1 2 AGLQFPVGR 9 0 Q71UI9;P0C0S5;C9J0D1;A0A494C189;Q71UI9-2;A0A3B3IS11;Q71UI9-5;Q8IUE6;Q96QV6;Q9BTM1-2;A0A0U1RR32;A0A0U1RRH7;Q99878;Q96KK5;Q93077;Q7L7L0;Q6FI13;P20671;P0C0S8;P04908;Q9BTM1;Q16777;P16104 Q71UI9;A0A0U1RR32;P16104 H2AFV;H2AFZ;HIST2H2AB;HIST1H2AA;H2AFJ;HIST1H2AJ;HIST1H2AH;HIST1H2AC;HIST3H2A;HIST2H2AA3;HIST1H2AD;HIST1H2AG;HIST1H2AB;HIST2H2AC;H2AFX Histone H2A.V;Histone H2A.Z;Histone H2A;Histone H2A type 2-B;Histone H2A type 1-A;Histone H2A.J;Histone H2A type 1-J;Histone H2A type 1-H;Histone H2A type 1-C;Histone H2A type 3;Histone H2A type 2-A;Histone H2A type 1-D;Histone H2A type 1;Histone H2A type 1-B/E;Histone H2A type 2-C;Histone H2AX 0 ; 106.36 0.011863 245670000.0 463970.0 511910.0 474290.0 480730.0 519230.0 518100.0 506850.0 443350.0 408250.0 416470.0 False True 457353.7027183216 510724.7038466567 435295.70701234567 516084.4878682678 488689.91224545625 495942.0707500889 533092.2129639034 463949.65952874924 362268.5859369141 488456.2845886071 0.936324738054131 1.0455893801771938 0.8911661508848537 1.0565622843872917 1.0004782979853477 1.0153253963510502 1.0913816236654426 0.9498284169268124 0.7416602004456301 1.0 18.8978699254138 -8.007875517136545 24.606051130586714 0.862468148149181 1.005743405314297 0.31163872995536124 0.07942302539657232 291.12606547381324 909580.4396598134 0.04326912664679865 0.01927621002153116 9.8202938410821e-09 8.007875517136545 0.14327525716511602 AGLQMKS(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 1 AGLQMKSPEK 10 1 Q9BRQ0 Q9BRQ0 PYGO2 Pygopus homolog 2 1 AGLQMKS(1)PEK 137.01 0.00056196 5310800.0 29224.0 25368.0 25919.0 26630.0 29123.0 21336.0 23363.0 22506.0 32176.0 23900.0 True False 28807.260400974745 25309.26195460526 23788.03987023334 28588.459035075837 27410.042398020963 20423.509016645214 24572.621823963054 23551.710922192407 28552.00005169907 28031.083155251792 1.0276898770348635 0.9028998920387212 0.8486307767160438 1.019884207711025 0.9778445679822232 0.7286022057559608 0.8766204890430438 0.8401998164591029 1.0185835450439837 1.0 14.774739872493466 -4.761094342418085 24.695281123615125 0.9041118207715723 1.0276900402395612 0.12374435172392995 0.08936545201525171 14.711727364453653 1051206.8312058127 0.02248511319398589 0.12768379672268845 1.7334274019111692e-05 4.761094342418085 0.12357821946798897 AGLQS(ph)LEASGR ddPTM_PC-9_AZD4547_30min_R2 1 AGLQSLEASGR 11 0 O60784-4;O60784;O60784-2;O60784-3 O60784-4 TOM1 Target of Myb protein 1 1 AGLQS(0.999)LEAS(0.001)GR 98.25299999999999 0.0050528 5711800.0 9318.7 5745.8 3274.5 15607.0 9719.0 14629.0 15141.0 11851.0 3983.2 10406.0 True False 12281.852758998879 7603.017484756976 3231.0779904797096 12009.047275746336 8369.684612151625 13714.246317404128 16488.51966799641 10019.700258888042 4193.74382013603 10041.689107339893 1.223086338136236 0.757145277401549 0.321766383717056 1.195919047819198 0.833493700380932 1.3657310210271107 1.6420065879100219 0.9978102440518918 0.4176333060411765 1.0 13.293714344238458 AGLRVS(ph)APEVSVGHK ddPTM_PC-9_AZD4547_30min_R2 1 AGLRVSAPEVSVGHK 15 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 AGLRVS(1)APEVSVGHK 66.068 0.013747 9509300.0 16072.0 20973.0 56273.0 114130.0 85491.0 71554.0 41694.0 92861.0 53150.0 69321.0 True False 21182.56168163262 27752.11210063144 55526.783251874964 87819.0917909226 73622.05033207682 67079.71706853072 45404.68522801944 78511.46618349545 55959.40049212443 66894.09288967031 0.3166581796178837 0.414866409002713 0.8300700533222916 1.3128078728231547 1.1005762564641253 1.0027748964197267 0.6787547788846804 1.1736681490394958 0.8365372497750934 1.0 16.029591198263063 -5.318915975629669 3.267551681597196 1.014135228843266 0.34357923927342504 0.7047065623273556 0.16558376603899888 0.13040024157039895 2.7518301297791363 0.04578195546136661 0.11789109902249027 4.79826273211409e-06 5.318915975629669 -0.6705559895698409 down AGLRVS(ph)APEVSVGHK ddPTM_PC-9_Lapatinib_30min_R1 1 AGLRVSAPEVSVGHK 15 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 AGLRVS(0.991)APEVS(0.009)VGHK 51.786 0.03795 5905100.0 28212.0 20959.0 35767.0 21500.0 30557.0 40120.0 25575.0 32429.0 43860.0 30240.0 True False 27809.691706552843 20910.470723217128 32826.375324612665 23081.181721897487 28759.697337373444 38404.1611242879 26899.14836056391 33935.76972788492 38920.02493372458 35466.943707732826 0.7841017240087006 0.5895763360815901 0.9255484654984681 0.6507801154815919 0.8108873878270767 1.0828156336435235 0.7584287099059825 0.9568281385487957 1.0973605522496397 1.0 15.114187393846429 -6.747646604311529 0.5467092445176424 1.027171075897892 0.6928432114871363 0.436547261811558 0.12432768567705046 0.9166557470073831 0.5912325407705022 0.10601609225881412 0.13173147474966415 1.7879418736501916e-07 6.747646604311529 -0.3343278644107557 AGLS(ph)PAEPLLSR ddPTM_PC-9_AZD4547_30min_R2 3 AGLSPAEPLLSR 12 0 O95402;B8ZZF3 O95402 MED26 Mediator of RNA polymerase II transcription subunit 26 1 AGLS(0.994)PAEPLLS(0.006)R;AGLS(0.999)PAEPLLS(0.001)R;AGLS(0.999)PAEPLLS(0.001)R 105.25 0.0018131 14129200.0 61733.0 57539.0 88771.0 122589.0 83207.0 84737.0 68631.0 97573.0 72686.0 89237.0 True False 81362.80987383195 76137.35651352855 87593.83853805909 94328.0000311697 71655.14430736704 79438.38199452261 74739.02604413603 82495.33485448327 76528.03356858993 86112.83979162895 0.9448394695925618 0.8841580035887967 1.017198349862968 1.0953999456924115 0.8321075519139092 0.9224917234960917 0.8679196531549227 0.9579911085745271 0.8886948073454342 1.0 16.393940745192985 -6.282458780606865 24.999807132270508 0.907800860565442 0.9804388615028948 0.2267811195987769 0.06635151547815775 1318.870030475208 1568618.3074651987 0.021143265655373514 0.02399925947476211 5.218446307679926e-07 6.282458780606865 0.07263800093745287 AGLS(ph)PAEPLLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGLSPAEPLLSR 12 0 O95402;B8ZZF3 O95402 MED26 Mediator of RNA polymerase II transcription subunit 26 1 AGLS(0.999)PAEPLLS(0.001)R 125.36 0.00029532 2570300.0 11920.0 12546.0 8586.7 12287.0 14755.0 16128.0 18316.0 13345.0 14342.0 10696.0 True False 13937.820569268486 13791.483966374532 8791.43949324109 11598.599224991474 11863.863669653758 15282.21928827864 16580.975883643394 12994.70789019628 14551.724617601702 12635.100130510591 1.1031032936266292 1.0915215410973724 0.6957949998363665 0.9179665459859533 0.9389607954910867 1.2095051982513318 1.3122947750611413 1.028461013840114 1.1516904866042925 1.0 13.625149476932151 -6.752258757888029 24.731808933582037 1.1529131384668574 0.9415179830889294 0.33710787893995 0.13305236393129968 196.40976055066844 529110.4164669774 0.046436985893587586 0.045798195088925804 1.7690546201850806e-07 6.752258757888029 -0.21139515537792797 AGLS(ph)PAEPLLSR ddPTM_PC-9_Lapatinib_30min_R1 4 AGLSPAEPLLSR 12 0 O95402;B8ZZF3 O95402 MED26 Mediator of RNA polymerase II transcription subunit 26 1 AGLS(0.985)PAEPLLS(0.015)R;AGLS(0.597)PAEPLLS(0.403)R;AGLS(0.981)PAEPLLS(0.019)R;AGLS(0.692)PAEPLLS(0.308)R 97.95700000000001 0.0038085999999999997 17985300.0 73420.5 77422.0 96425.0 66084.0 91127.0 95618.0 87083.0 85142.0 97979.0 78207.0 True False 72373.51020632945 77242.73411579352 88497.30871126382 70944.0378097615 85767.08902257531 91528.6410364446 91591.73163960844 89098.00814615251 86943.57325538991 91724.97574572271 0.7890273027377098 0.8421123416802372 0.964811470286931 0.7734429715896626 0.9350461891681097 0.9978595283598398 0.9985473519613278 0.9713603892700653 0.9478724038740804 1.0 16.485026997540245 -6.484644529435434 6.405075235102121 0.9808884561681064 0.8509267281836221 0.6366645649512539 0.050048316290537645 0.1415402469209229 16.929094061044996 0.015820272258853126 0.017546599055255165 3.2760873331785485e-07 6.484644529435434 -0.12996172798448424 AGLS(ph)PANCQSDR ddPTM_PC-9_AZD4547_30min_R2 3 AGLSPANCQSDR 12 0 Q14692 Q14692 BMS1 Ribosome biogenesis protein BMS1 homolog 1 AGLS(1)PANCQSDR;AGLS(1)PANCQSDR;AGLS(0.811)PANCQS(0.189)DR 185.66 6.7901e-05 127624300.0 139984.0 122172.0 136061.0 191879.0 173611.0 164257.0 130511.0 185923.0 154745.0 159038.0 True False 184496.00015192 161661.70979632603 134256.74223932196 147644.2610509982 149508.10939399665 153985.98382376437 142126.226166692 157192.87243551103 162924.50478182125 153470.12802739965 1.2021622873669666 1.053375740766072 0.8748069996745722 0.962039081798633 0.9741837797079596 1.0033612782043984 0.9260839747349245 1.024257127142337 1.0616040194658185 1.0 17.227598346054066 -4.8642633544373926 3.5606690011673856 0.9767242525733792 1.2101457534066093 0.6535198217423869 0.049489158223209734 0.1537980749105255 3.2756981823470923 0.012939329105103451 0.08341354419010218 1.366899691721719e-05 4.8642633544373926 0.2334215008332301 AGLS(ph)PANCQSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 AGLSPANCQSDR 12 0 Q14692 Q14692 BMS1 Ribosome biogenesis protein BMS1 homolog 1 AGLS(0.966)PANCQS(0.034)DR;AGLS(0.985)PANCQS(0.015)DR;AGLS(1)PANCQSDR;AGLS(1)PANCQSDR;AGLS(1)PANCQSDR 153.0 0.00014843 91523500.0 181900.0 166205.0 199251.0 185479.0 236893.0 176270.0 184712.0 164254.0 167524.0 136885.0 True False 212692.07731123638 182704.73398942157 204001.8995036253 175087.21296103107 190475.51720062955 167026.09089439962 167214.7421609268 159942.5065414988 169973.7215757292 161701.16691893656 1.3153403983649814 1.1298912523062647 1.2615981899864381 1.0827826186857707 1.1779476971623712 1.03293064655577 1.034097312635686 0.9891240093627808 1.0511595235483973 1.0 17.302970564516713 -5.993212319707649 0.49881102123401583 0.9950309681120161 1.2985177934037173 0.7111575303242993 0.05705762164571875 0.8308297732859706 0.35608365177240564 0.04240923875483602 0.13086330886776726 1.015751986373672e-06 5.993212319707649 0.30348682529170123 AGLS(ph)PANCQSDR ddPTM_PC-9_Lapatinib_30min_R1 3 AGLSPANCQSDR 12 0 Q14692 Q14692 BMS1 Ribosome biogenesis protein BMS1 homolog 1 AGLS(0.994)PANCQS(0.006)DR;AGLS(0.998)PANCQS(0.002)DR;AGLS(0.999)PANCQS(0.001)DR 116.9 0.00065542 141558200.0 62657.0 107708.0 129700.0 109204.0 124468.0 123381.0 113983.0 130476.0 127371.0 101261.0 True False 61763.49969011347 107458.60874355957 119036.56665647842 117235.22645386454 117147.03695350332 118104.28224515877 119884.48201689773 136538.39128605623 113025.13670390857 118763.8289281986 0.5200531192662541 0.9048092311719432 1.0022964713308855 0.9871290569853703 0.9863864950356833 0.9944465693890807 1.0094359797828398 1.149663096232807 0.9516797978300322 1.0 16.85773598589757 -4.637715399217737 1.9359704699432077 1.0147356490008306 0.2194811065814864 0.8967830998412138 0.049792974341643766 0.365038787184 1.0610074739207995 0.013587222908929518 0.5935956749328304 2.3029504868244676e-05 4.637715399217737 -0.7952545424193442 AGLVGPEFHEK ddPTM_PC-9_Lapatinib_30min_R1 2 AGLVGPEFHEK 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 112.94 0.0013643 10430600.0 99027.0 81737.0 86885.0 84744.0 98958.0 98625.0 93916.0 79443.0 85893.0 80056.0 False True 97614.8568206725 81547.74299840641 79741.65068579878 90976.3564576968 93137.48499891357 94407.03865610399 98778.51094548282 83134.2118009301 76218.8258466121 93893.57293208515 1.0396329990688395 0.8685125131769275 0.8492769866525082 0.9689306053301602 0.991947394165962 1.0054685928757896 1.0520263300335906 0.8854089710811465 0.8117576471580489 1.0 16.51873878752064 -4.136223541185456 5.238345340267795 0.9396654980827517 11.66681416872889 0.14161318560264036 0.07534453502365611 2591.7760398030323 493.7979379229905 0.02040382295620127 327546.7708475114 7.307628465095979e-05 4.136223541185456 10.72714867064614 AGLYGLPR ddPTM_PC-9_Lapatinib_30min_R1 1 AGLYGLPR 8 0 P49327;A0A0U1RQF0;A0A0U1RRG3 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 90.939 0.041924 4296600.0 25190.0 24253.0 22346.0 19904.0 22389.0 26378.0 22387.0 21812.0 24623.0 23668.0 False True 24830.785980719756 24196.843668599882 20508.798138054484 21367.806557797576 21072.123038467587 25249.874430121297 23546.08931956771 22825.465148620842 21849.698448315074 27758.982264372356 0.894513557602188 0.8716761817185081 0.7388166447433766 0.7697618865956184 0.7591100724723936 0.9096109572622406 0.8482331627045369 0.8222731269912765 0.7871217409997904 1.0 14.760667054488007 -6.759330693000054 24.999538847438775 0.8607639492858193 0.8045494360033906 0.17337955696208796 0.07002121876887935 125.74894925869845 1490822.26637417 0.02443153529061508 0.023302926456370453 1.7404810815116758e-07 6.759330693000054 -0.05621451328242877 AGMS(ph)SNQSISSPVLDAVPR ddPTM_PC-9_AZD4547_30min_R2 1 AGMSSNQSISSPVLDAVPR 19 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AGMS(0.84)S(0.039)NQS(0.098)IS(0.017)S(0.005)PVLDAVPR 77.279 0.0030493 8864100.0 17014.0 15010.0 24138.0 24250.0 28266.0 19969.0 19288.0 25980.0 19555.0 21224.0 True False 22424.098086815433 19861.688963451958 23817.914348510978 18659.537158765193 24341.753806675348 18720.33527324103 21004.594634192923 21965.38796100848 20588.637377676267 20480.954220082825 1.0948756510977031 0.9697638474273996 1.1629299149136352 0.9110677636527491 1.188506821757688 0.9140362832745654 1.025567188348902 1.0724787392703645 1.0052577217075096 1.0 14.321995312490461 -6.796113328207082 24.999973673159676 1.009379263960414 1.0569558010459648 0.11140348064747763 0.08502867977970262 528.6343478656659 381142.384085458 0.028112059392832362 0.02479345677175414 1.5991406818569945e-07 6.796113328207082 0.04757653708555076 AGMS(ph)SNQSISSPVLDAVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGMSSNQSISSPVLDAVPR 19 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AGMS(0.668)S(0.085)NQS(0.205)IS(0.021)S(0.021)PVLDAVPR;AGMS(0.372)S(0.344)NQS(0.211)IS(0.037)S(0.037)PVLDAVPR 89.959 0.00090323 75499300.0 46046.0 55945.0 56328.0 57309.0 55133.0 46975.5 57169.0 43153.0 42000.0 39493.0 True False 53840.67835004505 61498.84987237555 57671.07314512961 54098.16252828486 44330.08442555206 44512.02208435847 51753.53845228271 42020.27947438292 42614.17054380639 46652.76827358404 1.1540725307940831 1.3182250946338316 1.2361768717974322 1.1595916926309513 0.9502133756691316 0.9541132012430286 1.109334780495477 0.9007028099161234 0.9134328384096253 1.0 15.509675069545631 -6.108542715207506 3.0828017086004063 0.9719400031334723 1.2418980736172331 0.7741306100233666 0.06580625645050753 0.12179576458634715 2.20927989104673 0.02079563837702211 0.028530294744709184 7.78856206072578e-07 6.108542715207506 0.26995807048376086 AGMS(ph)SNQSISSPVLDAVPRT(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGMSSNQSISSPVLDAVPRTPSR 23 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 AGMS(0.248)S(0.248)NQS(0.032)IS(0.218)S(0.248)PVLDAVPRT(0.626)PS(0.38)R 49.342 0.02951 49009000.0 26847.0 19617.0 49815.0 33640.0 39764.0 37573.0 38121.0 34095.0 28649.0 30347.0 True False 31391.6668475798 21564.446115763527 51002.77852443956 31755.259862351526 31972.529648262418 35602.605736513724 34509.90290786037 33200.0423766386 29067.9374264169 35848.67087328018 0.8756717078450346 0.6015410220365128 1.422724393457346 0.8858141484408651 0.8918748971553407 0.9931360039083106 0.9626550180855475 0.926116410117293 0.8108511896903463 1.0 15.129632010050575 -10.29241565718645 14.980444390135641 0.9999883037239687 0.9351475369956378 0.010954054803912983 0.19404088326231075 0.0 0.0 0.18470884849002223 0.044798476018268876 5.1001663650611746e-11 10.29241565718645 -0.06484076672833095 AGMSSNQS(ph)ISSPVLDAVPR ddPTM_PC-9_AZD4547_30min_R2 3 AGMSSNQSISSPVLDAVPR 19 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AGMS(0.001)S(0.001)NQS(0.475)IS(0.475)S(0.047)PVLDAVPR;AGMS(0.001)S(0.001)NQS(0.48)IS(0.04)S(0.478)PVLDAVPR;AGMSS(0.008)NQS(0.865)IS(0.033)S(0.094)PVLDAVPR 124.99 2.4726e-05 804430000.0 89596.0 100676.0 111076.0 137913.0 117784.0 121489.0 102285.0 134457.0 105383.0 97029.0 True False 118085.6642874286 133217.54817351687 109603.0596642309 106119.28858460959 101431.72469983203 113892.27362465709 111388.16684769947 113679.76016448496 110953.33023634135 93632.04424332915 1.261167213016837 1.422777311443865 1.1705721107551235 1.1333650722057167 1.083301400920322 1.2163813632934901 1.1896372416928767 1.2141116973699324 1.1849931413224086 1.0 16.51471473584577 -1.5228787452803376 0.032200498222923694 0.39640904561863805 2.3760000537699715 0.4316782997918347 0.07962749820794818 1321.756275167271 3.2712915241050253 62.075790202655845 160.2161792551047 0.029999999999999995 1.5228787452803376 1.9795910081513335 AGMSSNQS(ph)ISSPVLDAVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AGMSSNQSISSPVLDAVPR 19 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AGMS(0.081)S(0.081)NQS(0.29)IS(0.274)S(0.274)PVLDAVPR;AGMS(0.063)S(0.063)NQS(0.678)IS(0.118)S(0.078)PVLDAVPR;AGMS(0.072)S(0.171)NQS(0.358)IS(0.199)S(0.199)PVLDAVPR;AGMS(0.293)S(0.222)NQS(0.388)IS(0.048)S(0.048)PVLDAVPR 93.15299999999999 0.00073581 377165000.0 82886.0 105655.0 98762.0 91847.0 101288.0 86729.0 102417.0 80029.0 78840.0 76465.0 True False 96916.96272687832 116143.73015043026 101116.86063697057 86701.11036199162 81441.34350199196 82180.77856232143 92715.32032513138 77928.32354773465 79992.8858493736 90327.49920339297 1.0729508021543657 1.2858069931605896 1.1194471398934989 0.9598528812002676 0.9016229190471463 0.9098090757198166 1.0264351514521806 0.8627308874372935 0.8855872968347255 1.0 16.46287764659948 -5.718047131827196 3.3175775773848764 0.9281893932668488 1.1840937524667987 0.7049286852845678 0.06725050214323113 0.11664147746542003 2.6206979937474646 0.01847109248406984 0.03288623726624846 1.9140481915874155e-06 5.718047131827196 0.2559043591999499 AGMSSNQS(ph)ISSPVLDAVPR ddPTM_PC-9_Lapatinib_30min_R1 2 AGMSSNQSISSPVLDAVPR 19 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AGMS(0.001)S(0.023)NQS(0.843)IS(0.066)S(0.066)PVLDAVPR;AGMS(0.086)S(0.084)NQS(0.596)IS(0.117)S(0.117)PVLDAVPR 81.01 0.0020227 13082200.0 33226.0 31653.0 32605.0 28454.0 44050.0 38932.0 25268.0 33923.0 35507.0 26659.0 True False 32752.191147097856 31579.709423254506 29924.34275893969 30546.602079761444 41459.06560563211 37266.96911492463 26576.25340272647 35499.186422000035 31507.827754714046 31266.9726291154 1.0475011935309477 1.0100021450061298 0.9570591663573635 0.9769606556445712 1.3259699331116555 1.1918956643798033 0.8499784650714475 1.1353573255424048 1.0077031802360796 1.0 14.93235191910672 AGMSSNQSIS(ph)SPVLDAVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGMSSNQSISSPVLDAVPR 19 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AGMSSNQS(0.159)IS(0.565)S(0.276)PVLDAVPR;AGMS(0.03)S(0.007)NQS(0.314)IS(0.586)S(0.062)PVLDAVPR 159.18 8.3727e-06 312061900.0 73556.0 119749.0 87411.0 85824.0 94296.0 75550.0 90620.0 80518.0 70486.0 67145.0 True False 86007.57800277782 131636.88932642943 89495.20974806369 81015.5595251623 75819.37570949992 71588.0250018262 82035.81756801522 78404.48781587291 71516.72440358895 79317.85698047237 1.0843406677509255 1.6596122782141949 1.1283109901733341 1.0214037873603659 0.9558928921663409 0.9025461318180947 1.0342666921549835 0.9884846968971398 0.901647209419639 1.0 16.27535807873231 -5.502306185796992 5.077788895303679 0.9758762903859276 1.3809050162128143 0.5770110014062698 0.13576829500925897 0.11131098011573534 8.085118034031783 0.033928176968131586 0.06777108434301747 3.145529874311853e-06 5.502306185796992 0.40502872582688665 AGMSSNQSIS(ph)SPVLDAVPR ddPTM_PC-9_Lapatinib_30min_R1 4 AGMSSNQSISSPVLDAVPR 19 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AGMS(0.005)S(0.018)NQS(0.046)IS(0.465)S(0.465)PVLDAVPR;AGMSSNQS(0.111)IS(0.594)S(0.296)PVLDAVPR;AGMSSNQS(0.406)IS(0.561)S(0.032)PVLDAVPR;AGMSSNQS(0.027)IS(0.645)S(0.328)PVLDAVPR 188.9 3.5499000000000005e-11 343232300.0 81985.9 97652.0 96741.0 79457.0 97577.0 101239.4 91147.0 89743.0 90517.0 73194.3 True False 80816.76603162715 97425.8927937209 88787.32841105924 85300.53284078192 91837.71270376311 96909.62686256814 95866.14567430379 93912.78740292876 80322.0222737333 85845.83722972583 0.9414174133494586 1.1348936178816278 1.0342648085947592 0.9936478645145639 1.0697980900110842 1.1288797452488617 1.1167244536012075 1.0939701962672406 0.935654247960671 1.0 16.38946055741532 -4.73629354534973 24.721163416851756 1.0612745006867024 0.941416773306219 0.23045566023305608 0.062485601483828104 3267.837507928136 3212455.623516752 0.015741304024682604 1.1218605828089279 1.8352974223628476e-05 4.73629354534973 -0.11985772738048339 AGMSSNQSIS(ph)SPVLDAVPRT(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 1 AGMSSNQSISSPVLDAVPRTPSR 23 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 AGMSSNQSIS(0.557)S(0.442)PVLDAVPRT(0.87)PS(0.13)R 116.35 1.0592000000000001e-07 10984000.0 18241.0 16634.0 25970.0 39091.0 37177.0 25871.0 25564.0 34246.0 23621.0 31733.0 True False 24041.25856362996 22010.615204401067 25625.620831503442 30079.173899929494 32015.615271731764 24253.282280235297 27839.1464759699 28954.06759479201 24869.55783677276 30622.03732877347 0.785096638264496 0.7187835011787139 0.8368359216721603 0.9822721322224409 1.0455089884450257 0.7920205314832569 0.9091213029712862 0.9455304127523161 0.8121457618825547 1.0 14.902282650184011 -5.521968593421405 4.869120233899544 0.9227745689731068 0.75568183666568 0.46518603826553107 0.07547939280699023 0.16063161762798342 10.696426993338624 0.02080830549525029 0.04034322039486943 3.006293698863714e-06 5.521968593421405 -0.16709273230742683 AGMSSNQSIS(ph)SPVLDAVPRT(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGMSSNQSISSPVLDAVPRTPSR 23 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 AGMS(0.013)S(0.013)NQS(0.003)IS(0.486)S(0.486)PVLDAVPRT(0.735)PS(0.265)R 64.76100000000001 0.0015176999999999999 12390000.0 29164.0 19889.0 26004.0 37899.0 44165.0 43095.0 43789.0 48435.0 33976.0 32745.0 True False 34100.8891847438 21863.448478178165 26624.033980719178 35775.6419002158 35511.18529110525 40835.022335588306 39640.988915093985 47163.632571124544 34472.83472372301 38681.40929072262 0.88158342237346 0.5652185088153422 0.6882901752781977 0.9248794849053303 0.9180426965369712 1.0556756613669247 1.0248072560428017 1.2192842359142355 0.8911990373626589 1.0 15.239352737438107 -6.0696796472392505 1.5654236579495098 1.0453231444428852 0.6944026579164059 0.5982790328306522 0.1110821545101414 0.24115262410679267 1.1863738927016556 0.03764947584058373 0.060517785912400264 8.517661028461525e-07 6.0696796472392505 -0.35092048652647934 AGMSSNQSIS(ph)SPVLDAVPRT(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 6 AGMSSNQSISSPVLDAVPRTPSR 23 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 AGMS(0.009)S(0.011)NQS(0.002)IS(0.82)S(0.164)PVLDAVPRT(0.803)PS(0.19)R;AGMS(0.004)S(0.005)NQS(0.021)IS(0.806)S(0.164)PVLDAVPRT(0.864)PS(0.136)R;AGMS(0.017)S(0.02)NQS(0.009)IS(0.632)S(0.323)PVLDAVPRT(0.897)PS(0.101)R;AGMSSNQSIS(0.852)S(0.148)PVLDAVPRT(0.921)PS(0.079)R;AGMSSNQSIS(0.552)S(0.465)PVLDAVPRT(0.924)PS(0.059)R;AGMS(0.001)S(0.003)NQS(0.004)IS(0.54)S(0.452)PVLDAVPRT(0.587)PS(0.413)R 126.04 1.0683e-06 169441100.0 279879.0 190140.0 291617.0 235801.0 253313.0 252265.0 215832.5 217827.3 269964.0 178419.8 True False 275887.8741364769 189699.74251216705 267641.37593417364 253142.59214907614 238413.6273725194 241476.21400843663 227007.25077346683 227948.35157565481 239557.81147305094 209259.42470056043 1.31840118805286 0.906529026272617 1.2789931747024288 1.209707006082571 1.1393208583731755 1.1539562165669563 1.0848125531182293 1.089309845431513 1.1447886364776447 1.0 17.674933075289196 -7.206241320039917 3.188259716812728 1.0861615947307524 1.1631819825213205 0.13554003919375102 0.10818741890899983 0.6473151415012153 13.143278257401994 0.04462948545954396 0.032076161244828004 6.219545938906983e-08 7.206241320039917 0.07702038779056819 AGMSSNQSISS(ph)PVLDAVPR ddPTM_PC-9_AZD4547_30min_R2 7 AGMSSNQSISSPVLDAVPR 19 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AGMS(0.001)S(0.002)NQS(0.325)IS(0.163)S(0.509)PVLDAVPR;AGMS(0.011)S(0.011)NQS(0.285)IS(0.163)S(0.531)PVLDAVPR;AGMSSNQS(0.333)IS(0.16)S(0.507)PVLDAVPR;AGMSSNQS(0.253)IS(0.178)S(0.569)PVLDAVPR;AGMSSNQSIS(0.002)S(0.998)PVLDAVPR;AGMSSNQS(0.003)IS(0.021)S(0.976)PVLDAVPR;AGMSSNQS(0.001)IS(0.07)S(0.929)PVLDAVPR 340.33 1.2104999999999996e-199 190002000.0 230766.8 242990.3 333599.4 328072.1 304140.2 322408.4 264870.7 394681.0 297892.1 271558.8 True False 304145.8421523756 321532.1625406982 329175.65398602444 252440.14600841785 261915.58307199492 302248.15178071975 288443.6791774641 333692.1203171199 313638.0682472246 262051.60906806568 1.160633370022072 1.2269803024074657 1.2561481883537065 0.9633222513159562 0.9994809190580645 1.1533917034724765 1.100713253405528 1.2733832144890442 1.1968561054160891 1.0 17.999491441979295 -11.97610151955365 1.843348088740071 7.963734809434105e-05 1.1460631864153092 0.17191271313066148 0.09729331169776888 2041643.304302426 152594.80181743714 8508905.401533563 0.027129424423421374 1.0565704991602706e-12 11.97610151955365 1.145983549067215 AGMSSNQSISS(ph)PVLDAVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AGMSSNQSISSPVLDAVPR 19 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AGMSSNQS(0.009)IS(0.089)S(0.903)PVLDAVPR;AGMSSNQS(0.008)IS(0.103)S(0.89)PVLDAVPR;AGMSSNQS(0.035)IS(0.206)S(0.759)PVLDAVPR 193.27 1.2005e-14 87030200.0 46952.1 49447.6 56671.9 50507.9 50828.0 45374.6 51980.8 34984.5 39718.2 36107.7 True False 54900.16318375428 54356.43094019621 58023.173025377575 47678.106111821144 40868.61827185094 42995.07609858185 47056.8023155979 34066.19394414174 40299.0035355479 42653.74018160409 1.2871125240133547 1.2743649374888657 1.3603302495475436 1.117794263969001 0.9581485257294495 1.0080024850229892 1.1032280431973183 0.7986683887298112 0.9447941344409522 1.0 15.38038463234432 -5.992679945732965 3.1377475544137625 0.968335950385221 1.3034962971390087 0.8024369751991638 0.07501205659697172 0.1110730435889687 2.2612665071152884 0.02376901810958671 0.035197389878615024 1.0169978955940063e-06 5.992679945732965 0.3351603467537877 AGMSSNQSISS(ph)PVLDAVPR ddPTM_PC-9_Lapatinib_30min_R1 9 AGMSSNQSISSPVLDAVPR 19 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AGMSS(0.007)NQS(0.221)IS(0.299)S(0.472)PVLDAVPR;AGMSSNQS(0.061)IS(0.011)S(0.928)PVLDAVPR;AGMSS(0.002)NQS(0.014)IS(0.068)S(0.916)PVLDAVPR;AGMSSNQS(0.301)IS(0.158)S(0.541)PVLDAVPR;AGMSSNQS(0.176)IS(0.302)S(0.521)PVLDAVPR;AGMSSNQS(0.361)IS(0.196)S(0.443)PVLDAVPR;AGMSSNQSIS(0.031)S(0.968)PVLDAVPR;AGMSSNQS(0.036)IS(0.071)S(0.893)PVLDAVPR;AGMSSNQSIS(0.024)S(0.976)PVLDAVPR 324.29 5.399199999999997e-177 599728400.0 291780.0 344006.0 318571.0 294344.7 356181.0 340407.0 322825.0 334328.0 344381.0 289447.5 True False 287619.16369410127 343209.47524266504 292379.32209962135 315991.7911431351 335231.133858789 325848.5861374743 339539.2989051434 349862.09940437006 305593.18528730044 339478.1147104488 0.8472391922507889 1.0109914612180488 0.8612611812958858 0.9308163838857598 0.9874896770435934 0.9598515250840263 1.0001802301593044 1.0305880828364389 0.9001852315220679 1.0 18.372959045029283 -6.169483831638002 4.494563014910296 0.9812608820987903 0.9141717319882501 0.28977545366811597 0.051907442328221295 0.3048438807670946 10.681494037567717 0.014850806375119522 0.019390297214561616 6.768869922963487e-07 6.169483831638002 -0.06708915011054017 AGMSSNQSISS(ph)PVLDAVPRT(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 3 AGMSSNQSISSPVLDAVPRTPSR 23 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 AGMS(0.044)S(0.044)NQS(0.045)IS(0.416)S(0.456)PVLDAVPRT(0.921)PS(0.074)R;AGMS(0.003)S(0.004)NQS(0.003)IS(0.367)S(0.622)PVLDAVPRT(0.648)PS(0.354)R;AGMSSNQSIS(0.44)S(0.56)PVLDAVPRT(0.95)PS(0.05)R 130.77 3.118e-06 111385000.0 99982.0 83089.0 154546.0 221284.0 199399.0 138773.0 93678.0 173886.0 113504.0 148287.0 True False 131774.1962452086 109945.89435604647 152496.6190614376 170270.3926037197 171715.8907272785 130095.50237235115 102015.16052166738 147015.91420276804 119503.58971699151 143095.51726504994 0.9208827695219037 0.768339193689752 1.0656980873759616 1.1899072441824634 1.2000088752550944 0.9091514874737872 0.7129165362511594 1.0273970632529075 0.835131609997537 1.0 17.12661895208644 -6.972968090135998 24.99068770771442 0.8839856730488648 1.0283807133641898 0.17695804561373296 0.1420544094147004 402.7777447143196 372362.1957043402 0.054776279182819416 0.04830706646309518 1.0642212091936272e-07 6.972968090135998 0.14439504031532502 AGMSSNQSISS(ph)PVLDAVPRT(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AGMSSNQSISSPVLDAVPRTPSR 23 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 AGMS(0.034)S(0.039)NQS(0.006)IS(0.424)S(0.497)PVLDAVPRT(0.93)PS(0.07)R;AGMSSNQSIS(0.447)S(0.553)PVLDAVPRT(0.949)PS(0.051)R;AGMS(0.003)S(0.003)NQS(0.003)IS(0.446)S(0.544)PVLDAVPRT(0.884)PS(0.116)R 112.85 1.0246e-06 53154300.0 97043.0 79281.6 113358.3 116452.3 140852.6 123709.0 128170.2 119651.3 116283.1 109566.8 True False 113470.46321338294 87152.15329415906 116061.19178574675 109927.85517445045 113253.54414884957 117221.48226275187 116028.99078410957 116510.58015603176 117983.52035148814 129430.39350968866 0.8766910162016079 0.6733515284231535 0.8967074010870473 0.8493202577354575 0.8750150646831794 0.905671991594286 0.8964586109786037 0.9001794477841113 0.9115596202112787 1.0 16.98181691260902 -1.522878838147764 0.09821952541015092 1.0695272509765017 0.24008189386686943 0.4789503392028053 0.056224760177643676 106.61027225433998 0.7469272333887768 0.7365450744442783 11.909212192596183 0.029999993584946132 1.522878838147764 -0.8294453571096323 AGMSSNQSISSPVLDAVPRT(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 2 AGMSSNQSISSPVLDAVPRTPSR 23 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AGMSSNQSISSPVLDAVPRT(0.499)PS(0.499)R;AGMSSNQSISSPVLDAVPRT(0.827)PS(0.173)R 114.8 2.2098e-08 59231300.0 50882.0 35453.0 64931.0 91492.0 89760.0 69203.0 58526.0 83537.0 70606.0 81827.0 True False 67061.41758865296 46912.488928798295 64069.97251483825 70399.9329373091 77298.37337038078 64875.725470183745 63734.70062011484 70628.27613929038 74338.08901499407 78962.26163620029 0.8492844075011728 0.594112781937989 0.8113999167099001 0.8915642925940994 0.9789280571333496 0.8216041958003066 0.8071539403690995 0.8944560942883482 0.9414381943299575 1.0 16.2688756915905 -1.5682790828912636 0.14337515828271633 1.0150631637634666 3.1198425431945e-14 0.37961269693203004 0.0862784963498045 79.56105644516042 0.7675869058121582 0.3691348667017995 16.584911430892134 0.027022213259129527 1.5682790828912636 -1.0150631637634353 AGMSSNQSISSPVLDAVPRT(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AGMSSNQSISSPVLDAVPRTPSR 23 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AGMSSNQSISSPVLDAVPRT(0.613)PS(0.387)R;AGMSSNQSISSPVLDAVPRT(0.5)PS(0.5)R;AGMSSNQSISSPVLDAVPRT(0.599)PS(0.401)R 112.75 2.0069000000000003e-07 92367000.0 55167.0 38331.0 70935.0 76900.0 87325.0 74643.0 82666.0 73549.0 75848.0 56058.0 True False 64505.68350208345 42136.248359246136 72626.35942248552 72591.54231316378 70214.29311775771 70728.58967850842 74835.27802998843 71618.41668160715 76957.13350968149 66220.87164511613 0.9740989796657383 0.6362986066546851 1.0967291371774295 1.0962033647365543 1.060304574274448 1.0680709558996682 1.1300859709464066 1.0815082148935908 1.1621280662402331 1.0 16.014998380163707 -5.283973387650372 24.929930963724743 1.090045162086083 0.8051988027355957 0.6332260324399444 0.08572324518100582 362.7987231836647 401372.7429846947 0.020387842448366795 0.0424900106365812 5.200278614082425e-06 5.283973387650372 -0.2848463593504872 AGMSSNQSISSPVLDAVPRT(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 2 AGMSSNQSISSPVLDAVPRTPSR 23 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AGMSSNQSISSPVLDAVPRT(0.619)PS(0.381)R;AGMSSNQSIS(0.001)S(0.001)PVLDAVPRT(0.755)PS(0.243)R 71.15899999999999 0.00057566 72636000.0 71448.0 61693.0 80039.0 65440.0 72935.0 68670.0 60153.0 56212.0 76649.0 53818.0 True False 70429.13841804133 61550.153648906635 73458.50237947488 70252.67590144045 68645.10669572707 65733.14417758845 63267.42800911051 58823.814731995015 68015.98247024749 63120.36959202264 1.1157909700665378 0.9751234672219908 1.1637844146710892 1.112995319189627 1.0875270081498805 1.0413935248233404 1.002329809188989 0.9319307715116637 1.0775599526724504 1.0 15.945818032413767 -6.987081572810408 2.632136374837155 0.9976876012378226 1.0900462720604616 0.36002420051525064 0.05530773020641484 0.31287387857326004 4.3792016977943256 0.02250056590157576 0.018167824873212092 1.0301926029045072e-07 6.987081572810408 0.09235867082263893 AGMSSNQSISSPVLDAVPRT(ph)PSRER ddPTM_PC-9_AZD4547_30min_R2 2 AGMSSNQSISSPVLDAVPRTPSRER 25 2 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AGMSSNQSIS(0.003)S(0.013)PVLDAVPRT(0.492)PS(0.492)RER;AGMSSNQSIS(0.005)S(0.005)PVLDAVPRT(0.495)PS(0.495)RER 55.621 0.0030586 13266800.0 11151.4 7967.900000000001 21437.1 37792.0 28971.2 15499.8 8530.5 14320.6 8598.7 18230.6 True False 14697.313236470753 10543.367854223112 21152.830047247688 29079.638280579566 24949.04895931342 14530.595055745467 9289.697974231785 12107.680324650413 9053.209727406034 17592.35224296277 0.8354376398045303 0.5993154132325103 1.2023878191564272 1.6529704430066705 1.4181758422494892 0.8259608979554137 0.5280532043659947 0.6882354421645738 0.5146105308929035 1.0 14.102660775512996 -6.9632903991660084 7.579900414671614 0.6592308185880221 1.1426028260661885 0.3502617447931251 0.29744218748023665 0.2587470220643172 43.77086730572845 0.11902924870850512 0.10429530027102227 1.0882022031506463e-07 6.9632903991660084 0.48337200747816633 AGMSSNQSISSPVLDAVPRTPS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 AGMSSNQSISSPVLDAVPRTPSR 23 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AGMSSNQSISSPVLDAVPRT(0.194)PS(0.806)R 110.03 1.6617e-06 48320000.0 29391.0 33571.0 47616.0 64356.0 59747.0 46053.0 42224.0 57354.0 45448.0 63961.0 True False 38736.72662922253 44422.16923331413 46984.58072825828 49519.718490288404 51452.16035829027 43173.29862980466 45981.85420127344 48491.257163805974 47850.288496069064 61721.744858213206 0.6276025850890685 0.7197166790303879 0.7612322178543552 0.8023058745997019 0.8336148058757223 0.6994827953905399 0.7449862978906812 0.785643005964912 0.7752581947576246 1.0 15.913491226660774 -14.522878745279984 0.1939222788663863 2.077429972122234 0.7107219035861423 0.698562867743236 0.05106156851897218 86.02769485221867 0.8432124280665642 35.86431228864233 0.14283852560897278 3.000000000002443e-15 14.522878745279984 -1.3667080685360915 AGMSSNQSISSPVLDAVPRTPS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGMSSNQSISSPVLDAVPRTPSR 23 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AGMSSNQSISSPVLDAVPRT(0.081)PS(0.919)R 72.822 0.00096195 13731000.0 9514.2 11570.0 11781.0 18439.0 15393.0 14652.0 17698.0 15138.0 19857.0 13584.0 True False 11124.76614598442 12718.593136533831 12061.903719691303 17405.92261004458 12376.852149575077 13883.623326628147 16021.517317575936 14740.643540036806 20147.37105924675 16046.671669115165 0.6932756134966058 0.7926000730115986 0.7516763580890549 1.0847060978723426 0.7713033833300557 0.8652026795905464 0.9984324256108733 0.918610652974719 1.2555482828270335 1.0 13.969986470391836 -5.385484031955564 0.3002961694285898 1.0836974400093722 0.5266598437398021 0.4627566087360848 0.12108062262516187 5.14588320071085 0.5049630316754401 0.1450885117875383 1.023676169420283 4.116384820581209e-06 5.385484031955564 -0.5570375962695701 AGMSSNQSISSPVLDAVPRTPS(ph)RER ddPTM_PC-9_Lapatinib_30min_R1 1 AGMSSNQSISSPVLDAVPRTPSRER 25 2 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AGMSSNQSIS(0.011)S(0.034)PVLDAVPRT(0.41)PS(0.545)RER 52.09 0.042724 5539600.0 15563.0 5333.7 10930.0 7426.9 7202.0 9921.1 7124.8 4414.4 7179.3 5131.3 True False 15341.068766095343 5321.350145351554 10031.377591020113 7973.09900141211 6778.392519676785 9496.797680213676 7493.687282085857 4619.509139559501 6370.691632619443 6018.238367972534 2.5490962351601816 0.8842039513872307 1.6668295567029114 1.3248227328187638 1.1263084153910534 1.578002913735207 1.2451629237494597 0.767584940494099 1.0585641915618649 1.0 12.555125534151784 -4.752873387009213 24.99775520680586 1.2082234418540074 2.5490987544624586 0.6951457322648813 0.2708565685426745 194.46751330013353 567463.0957323171 0.06938865373327242 0.7915468598701877 1.7665527614398438e-05 4.752873387009213 1.3408753126084512 AGMTHIVR ddPTM_PC-9_AZD4547_30min_R2 4 AGMTHIVR 8 0 P39023;H7C422;H7C3M2;F8WCR1 P39023 RPL3 60S ribosomal protein L3 0 ;;; 105.14 0.0032286999999999997 15546000.0 122078.0 95357.0 147132.0 195425.0 165247.0 142460.0 133797.0 155738.0 126229.0 151336.0 False True 160896.26461985704 126179.28544223109 145180.93354565898 150372.7855361523 142305.30642084786 133551.95367949895 145704.67380086664 131672.2706032153 132901.2072383889 146037.77270309365 1.10174416961954 0.8640181448039718 0.994132756604165 1.0296841889109887 0.9744417748014126 0.9145028112077596 0.9977190907799982 0.9016315995924934 0.9100467966502581 1.0 17.15598204520868 -6.55544255834486 10.368637458119299 0.9421795650327623 0.9894342497234889 0.12894437278199367 0.06313115827531188 1.0358893619027285 321.1956657118155 0.02021562016043643 0.020258484116032635 2.7832834785462815e-07 6.55544255834486 0.04725468469072658 AGMTHIVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGMTHIVR 8 0 P39023;H7C422;H7C3M2;F8WCR1 P39023 RPL3 60S ribosomal protein L3 0 ; 82.241 0.011364 8582300.0 73859.0 75814.0 87915.0 86057.0 106758.0 90486.0 89052.0 92772.0 84618.0 72139.0 False True 86361.86991825502 83340.31288272918 90011.22701949427 81235.50529055839 85839.53626871521 85740.75486850081 80616.34987935208 90336.83330005908 85855.37816847154 85217.22964799005 1.013432028651872 0.9779749145447004 1.056256198321712 0.9532755949251212 1.0073025915451106 1.0061434198538641 0.9460099819292062 1.0600770955969439 1.0074884917418403 1.0 16.378857530830054 -7.780185701620384 24.999970369834504 1.0253370556114791 0.9954667850689785 0.1296915201217259 0.033123455050643374 486.38125226506816 648624.6201283677 0.017099812000198642 0.008236863876797966 1.658877430088716e-08 7.780185701620384 -0.029870270542500688 AGMTHIVR ddPTM_PC-9_Lapatinib_30min_R1 7 AGMTHIVR 8 0 P39023;H7C422;H7C3M2;F8WCR1 P39023 RPL3 60S ribosomal protein L3 0 ;;;;;; 116.73 0.0030026999999999996 26393300.0 185179.0 178122.2 190423.9 186715.5 201080.2 182455.4 178974.8 181872.2 187741.6 163478.7 False True 182538.31350233 177709.7689896957 174767.98199951113 200447.18073464854 189253.05797488353 174652.20786631107 188241.23941357786 190322.64636910913 166596.16400130728 191735.7754733251 0.9520305381283699 0.9268472122690492 0.9115042905690045 1.0454344278725145 0.9870513601735896 0.910900469331605 0.9817742095802386 0.9926298099521205 0.8688840858730856 1.0 17.54876002522731 AGMTSS(ph)PDATTGQTFG ddPTM_PC-9_AZD4547_30min_R2 2 AGMTSSPDATTGQTFG 16 0 Q9UQR1;G5E9X2;Q9UQR1-2 Q9UQR1 ZNF148 Zinc finger protein 148 1 AGMT(0.023)S(0.117)S(0.86)PDATTGQTFG;AGMT(0.011)S(0.081)S(0.908)PDATTGQTFG 146.79 4.3162e-10 3968700.0 25844.0 24737.0 30226.0 48644.0 34798.0 28437.0 26673.0 33904.0 25093.0 32661.0 True False 34061.85441140576 32732.751491599654 29825.18349068246 37429.87734230821 29966.898357202626 26658.829894594364 29046.845327552244 28664.915836413827 26419.364751625195 31517.5483312347 1.0807266495931598 1.0385563987272657 0.9463040455188241 1.1875884808341592 0.9508004252825929 0.845840850767405 0.9216086550350769 0.9094906600970025 0.8382430154138267 1.0 14.943867695183412 -6.510536960360173 24.324984376659682 0.8985161021371345 1.0551735177177521 0.5454143744371119 0.06904751346971542 312.13169267150226 615196.1554051887 0.021043187978904504 0.0226718576296059 3.0864769618154156e-07 6.510536960360173 0.15665741558061763 AGMTSS(ph)PDATTGQTFG ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AGMTSSPDATTGQTFG 16 0 Q9UQR1;G5E9X2;Q9UQR1-2 Q9UQR1 ZNF148 Zinc finger protein 148 1 AGMT(0.015)S(0.162)S(0.823)PDATTGQTFG;AGMT(0.011)S(0.048)S(0.94)PDATTGQTFG;AGMT(0.04)S(0.174)S(0.786)PDATTGQTFG 115.37 0.00015619 25079800.0 59077.0 56952.0 62912.0 66221.0 77655.0 74518.0 73854.0 67664.0 69730.0 52055.0 True False 69077.56927606327 62605.81817734436 64412.06067508863 62510.852061378624 62439.06020108183 70610.14489855831 66858.01446334337 65887.89169593413 70749.66933380056 61492.159432846725 1.123355723935834 1.0181105811662674 1.047484122677959 1.0165662197900918 1.0153987236253945 1.1482788301762112 1.087260800075764 1.0714844348227488 1.1505478094498147 1.0 15.908114850676784 -6.742852871856888 24.999081172105686 1.0957163244177994 1.0413837261348846 0.18457862698454586 0.0491721531752668 363.3121948492444 488658.3173150467 0.015493536408210723 0.015467353933784834 1.8077864552654095e-07 6.742852871856888 -0.05433259828291481 AGMTSS(ph)PDATTGQTFG ddPTM_PC-9_Lapatinib_30min_R1 6 AGMTSSPDATTGQTFG 16 0 Q9UQR1;G5E9X2;Q9UQR1-2 Q9UQR1 ZNF148 Zinc finger protein 148 1 AGMT(0.01)S(0.09)S(0.901)PDATTGQTFG;AGMT(0.012)S(0.121)S(0.866)PDATTGQTFG;AGMT(0.019)S(0.149)S(0.833)PDATTGQTFG;AGMT(0.014)S(0.159)S(0.827)PDATTGQTFG;AGMT(0.035)S(0.164)S(0.801)PDATTGQTFG;AGMT(0.028)S(0.149)S(0.804)PDAT(0.018)TGQTFG 147.96 8.9117e-06 36190200.0 124138.0 121107.0 140194.0 121171.0 130360.0 127541.0 108702.0 114321.0 139493.0 95520.0 True False 122367.7693558791 120826.58418229198 128667.79048449009 130082.31955460669 122692.48109762109 122086.36874259239 114330.0576770292 119632.7710093289 123781.82941358966 112030.50472760022 1.0922718741061974 1.0785150390608276 1.1485067464200316 1.1611330313194523 1.0951702966611214 1.0897600527592266 1.0205261321906949 1.0678588952197747 1.1048939725350924 1.0 16.773532090890157 -6.87510506018703 2.5746953493413907 1.0542425426958706 1.1187210682962418 0.43743467067902764 0.03527149661799847 0.29818890011001575 4.01682905161968 0.014405985628491868 0.012462565133759169 1.3331988789822983e-07 6.87510506018703 0.06447852560037126 AGNALT(ph)PELAPVQIK ddPTM_PC-9_AZD4547_30min_R2 1 AGNALTPELAPVQIK 15 0 P0C1Z6-2;P0C1Z6 P0C1Z6-2 TFPT TCF3 fusion partner 1 AGNALT(1)PELAPVQIK 137.73 0.00010875 9917900.0 30758.0 30729.0 39179.0 45938.0 43171.0 46942.0 33501.0 45488.0 34073.0 36175.0 True False 40538.40419385615 40661.548311653234 38659.46086089615 35347.703835024986 37177.45183570306 44006.70931926889 36482.524099963535 38458.87481025224 35874.02921859184 34908.52426081307 1.1612752200860854 1.1648028432212552 1.1074504488376133 1.0125808691003566 1.0649963761841688 1.2606293233847494 1.0450892689530669 1.1017044009913832 1.0276581430531169 1.0 15.091291748568215 -8.230411066629816 0.015708504067869604 3.6459409405774037e-07 2.1439780292453556 0.2636082163873962 0.06682455424376615 701.8436138761064 9.732764367324451 669.8151279404658 655.9871353905276 5.882865691637469e-09 8.230411066629816 2.1439776646512616 AGNALT(ph)PELAPVQIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGNALTPELAPVQIK 15 0 P0C1Z6-2;P0C1Z6 P0C1Z6-2 TFPT TCF3 fusion partner 1 AGNALT(1)PELAPVQIK;AGNALT(1)PELAPVQIK 100.18 0.0046881 16818700.0 101112.0 118502.0 109397.0 118950.0 129089.0 119840.0 115943.0 95910.0 105767.0 89401.0 True False 118228.26454696961 130266.0954075654 112005.43937043265 112285.61714110346 103794.93712314032 113555.3794337372 104960.03968537188 93392.46412504495 107313.64228349469 105608.69360207349 1.1194936753260658 1.2334789018260122 1.060570257525026 1.0632232377022688 0.9828256896561255 1.0752465120116559 0.9938579496197 0.8843255317307638 1.0161440182930899 1.0 16.68836907523501 -5.705427688232393 0.7830456647791835 0.9759205487345336 1.2001076900633032 0.6020503491145959 0.055597310857084574 0.6375976768698248 0.6652736958882598 0.02619977135246624 0.10085164322409043 1.970481272914076e-06 5.705427688232393 0.2241871413287696 AGNALT(ph)PELAPVQIK ddPTM_PC-9_Lapatinib_30min_R1 2 AGNALTPELAPVQIK 15 0 P0C1Z6-2;P0C1Z6 P0C1Z6-2 TFPT TCF3 fusion partner 1 AGNALT(1)PELAPVQIK;AGNALT(1)PELAPVQIK 181.81 2.7077e-05 21203000.0 92775.0 88513.0 103120.0 88783.0 94748.0 84393.0 77713.0 84116.0 92202.0 71023.0 True False 91452.01148714864 88308.05358672266 94641.87165471126 95312.39799140602 89175.10892173504 80783.70811969167 81736.59888737074 88024.3364405554 81817.23982989683 83299.23091780132 1.0978734194724125 1.0601304791620942 1.136167412495113 1.1442170226692625 1.0705394028155188 0.96980136826723 0.9812407388013874 1.0567244795743282 0.9822088262811586 1.0 16.346015555137917 -6.58439673841365 5.023346738514616 1.0010879268215391 1.1080764352868533 0.7489636971433935 0.030648626958590955 0.10965531734070287 5.551094824332756 0.010842031188595983 0.010919726072247397 2.603773853415532e-07 6.58439673841365 0.10698850846531416 AGNPAVAAPQSPLS(ph)PEGAHFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGNPAVAAPQSPLSPEGAHFR 21 0 A0A0A0MQT0;P09455-2;P09455-3 A0A0A0MQT0 RBP1 Retinol-binding protein 1 1 AGNPAVAAPQS(0.055)PLS(0.945)PEGAHFR 61.903999999999996 0.035439 0.0 9880.5 12109.0 11140.0 12226.0 17673.0 15703.0 17314.0 13083.0 15279.0 13459.0 True False 11553.073501229646 13311.101494406914 11405.619848685259 11541.0168572268 14210.102516692024 14879.507036448387 15673.892577495186 12739.585112584333 15502.42646997186 15899.01015861462 0.7266536335263489 0.8372283155750114 0.7173792415312918 0.7258953068203109 0.8937727805018423 0.9358763148148672 0.985840780094259 0.8012816512153492 0.9750560767817438 1.0 13.956649328473514 -6.366463395273044 4.34436504969131 0.928521637553301 0.7557309563384005 0.6804023502440935 0.06079434393735971 0.14468416635171302 4.605273018270126 0.01905077449416616 0.021774387580712 4.300674805550175e-07 6.366463395273044 -0.1727906812149005 AGNPAVAAPQSPLS(ph)PEGAHFR ddPTM_PC-9_Lapatinib_30min_R1 1 AGNPAVAAPQSPLSPEGAHFR 21 0 A0A0A0MQT0;P09455-2;P09455-3 A0A0A0MQT0 RBP1 Retinol-binding protein 1 1 AGNPAVAAPQSPLS(1)PEGAHFR 99.859 0.00041813 0.0 13554.0 7696.9 19338.0 8626.4 14777.0 11956.0 10081.0 13651.0 17626.0 8493.6 True False 13360.717474500814 7679.078300946124 17748.10428683869 9260.814232826817 13907.845912699791 11444.669750797257 10602.944853288167 14285.275295425594 15640.774269991538 9961.707442989396 1.3412075741998917 0.7708596487994952 1.7816327560722547 0.9296412573673967 1.3961307328381252 1.1488662778238385 1.0643702311043117 1.4340187540318634 1.5700897019414894 1.0 13.282177326997017 -7.779777588898123 24.964076215801214 1.376540694123671 1.204817515627991 0.03408559606600048 0.29280780766908965 725.8458132355 988090.3134366988 0.14920403412109912 0.07188391276847321 1.660437033558896e-08 7.779777588898123 -0.17172317849568008 AGNS(ph)DSEEDDANGR ddPTM_PC-9_AZD4547_30min_R2 1 AGNSDSEEDDANGR 14 0 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;A0A0A0MT65;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 AGNS(0.993)DS(0.007)EEDDANGR 90.853 0.0047686000000000004 988220.0 0.0 668.62 809.88 1106.9 674.11 1080.7 2300.5 2346.2 1078.1 942.38 True False 0.0 884.7383394232676 799.1404620338087 851.7213064345237 580.5214624855982 1013.1236581597269 2505.240043340978 1983.6487003124735 1135.086165015228 909.3875630381483 0.0 0.9728946990076147 0.8787677493234919 0.9365878103600087 0.6383652977902511 1.1140724805769384 2.7548650819143483 2.181301769385712 1.2481874738016532 1.0 9.82875146341306 -7.0332610822969155 9.591762612396325 1.9011859937052369 0.7405494762830094 0.4972130324393653 0.5211718766430888 0.38841379431986356 109.09095263012603 0.19444319538355875 0.15285357419768553 9.26272813909332e-08 7.0332610822969155 -1.1606365174222275 AGNS(ph)DSEEDDANGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGNSDSEEDDANGR 14 0 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;A0A0A0MT65;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 AGNS(0.999)DS(0.001)EEDDANGR 199.05 6.7635e-08 1410300.0 2319.3 4396.6 3686.5 1842.8 4161.1 2616.0 3701.2 2467.3 2675.0 1942.2 True False 2711.911681736946 4833.065391882853 3774.4001411291033 1739.5538904382088 3345.762325706285 2478.8123547951977 3350.595541632505 2402.535989320442 2714.1168143971936 2294.305485553259 1.1820185667572438 2.1065483312120423 1.645116644185213 0.7582049998972673 1.4582898165801461 1.0804194865957206 1.4603964305235173 1.0471735365881687 1.182979699733708 1.0 11.163841782881764 -5.6251591194300525 9.333475416854501 1.1675587193203942 1.701567351637947 0.38772165756253296 0.28676435596760685 0.25635876136709146 21.164489744775995 0.07289191068334498 0.12638885643259049 2.370505026615227e-06 5.6251591194300525 0.5340086323175528 AGNSDS(ph)EEDDANGR ddPTM_PC-9_AZD4547_30min_R2 1 AGNSDSEEDDANGR 14 0 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;A0A0A0MT65;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 AGNS(0.019)DS(0.981)EEDDANGR 161.2 0.00050583 1235000.0 1023.7 1225.2 2508.4 2224.8 2194.3 2519.2 931.36 4113.4 2819.8 1845.2 True False 1349.21530571723 1621.221939908151 2475.1369770405568 1711.9067328173542 1889.6593213750712 2361.674025757364 1014.2492357166064 3477.768546528569 2968.848871264205 1780.6001096351688 0.7577306653056838 0.9104918791902842 1.3900577471870947 0.9614212217296284 1.0612485707204902 1.326335999294784 0.5696109026548462 1.9531440707600185 1.667330500093308 1.0 10.798147834440059 -7.767877089239831 24.99999440209908 1.6076778859545293 1.0223171642007918 0.3728504488831327 0.3182007532919722 149.83575624711855 581855.079881524 0.16187014526748272 0.08069351170929279 1.706565299949862e-08 7.767877089239831 -0.5853607217537375 AGNSDS(ph)EEDDANGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGNSDSEEDDANGR 14 0 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;A0A0A0MT65;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 AGNS(0.068)DS(0.932)EEDDANGR 137.32 6.9379e-05 1304400.0 2282.8 3479.0 3765.8 2139.5 3660.7 3364.0 3302.3 3093.7 1079.7 2902.7 True False 2669.232952644806 3824.3721280899904 3855.5909538760293 2019.6307513525878 2943.4121135548294 3187.5859180164525 2989.4822374184096 3012.4936530461005 1095.4885699082806 3428.9365322394437 0.7784433825322296 1.1153231015309248 1.124427622857731 0.5889962477764392 0.8584037895949279 0.9296135662022986 0.871839478307863 0.8785504265599913 0.31948347821789963 1.0 11.743545485677888 -6.164793434516226 0.6385188383315293 0.7583838507611975 0.9975764036298032 0.09009525724577305 0.2197006121583712 2.307710758814181 1.9228644550817338 0.14629557754239414 0.3177296638260774 6.842370166990689e-07 6.164793434516226 0.23919255286860563 AGNWPGS(ph)PQVSGPSPAAR ddPTM_PC-9_Lapatinib_30min_R1 2 AGNWPGSPQVSGPSPAAR 18 0 H7C3E5;O60244 H7C3E5 MED14 Mediator of RNA polymerase II transcription subunit 14 1 AGNWPGS(0.894)PQVS(0.106)GPSPAAR;AGNWPGS(0.815)PQVS(0.184)GPSPAAR 217.67 1.2937999999999998e-27 15382700.0 63151.0 53045.0 64142.0 41473.0 47655.0 54938.0 48795.0 52798.0 56370.0 38879.0 True False 62250.45515952492 52922.177561575074 58868.492355280156 44523.06276987232 44852.0265933348 52588.42980673304 51321.36634423138 55251.187828575275 50021.01699758444 45599.18334698891 1.3651660093521294 1.1605948544924924 1.2909988301175896 0.9764004418910793 0.983614690027043 1.1532756937017745 1.125488716622385 1.211670555767173 1.0969717728703035 1.0 15.476720366400006 -5.743562412568362 24.99999924806874 1.0881797933666344 1.2610874589793812 0.513220800924124 0.08601552434837587 232.85861745440548 325638.0251378554 0.02451336814569303 0.0423468782226353 1.8048353451555655e-06 5.743562412568362 0.17290766561274684 AGNWPGSPQVS(ph)GPSPAAR ddPTM_PC-9_AZD4547_30min_R2 1 AGNWPGSPQVSGPSPAAR 18 0 H7C3E5;O60244 H7C3E5 MED14 Mediator of RNA polymerase II transcription subunit 14 1 AGNWPGS(0.431)PQVS(0.566)GPS(0.003)PAAR 140.96 0.00016108 8010400.0 22210.0 20282.0 30577.0 42890.0 28877.0 24053.0 21100.0 28552.0 26212.0 27406.0 True False 29272.31800330143 26837.759863872936 30171.52900134313 33002.373143894394 24867.927003303073 22548.962107630137 22977.859123883776 24139.944459688766 27597.512807141426 26446.524281737184 1.1068493421464694 1.014793459358511 1.1408504452200652 1.247890754653321 0.9403098395230628 0.8526247860555902 0.8688423052911828 0.9127832528208162 1.043521353246372 1.0 14.690790509034528 -6.377330805067772 7.686081326915026 0.9229637945531514 1.1200824948796189 0.6052502127040973 0.07520084686896909 0.19544480085255056 11.777829516260775 0.02465157038985164 0.027947160412377856 4.1943937245169175e-07 6.377330805067772 0.1971187003264675 AGPDLPSLPSHALEDEGWAAAAPS(ph)PGSAR ddPTM_PC-9_AZD4547_30min_R2 4 AGPDLPSLPSHALEDEGWAAAAPSPGSAR 29 0 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 AGPDLPSLPSHALEDEGWAAAAPS(0.747)PGS(0.253)AR;AGPDLPSLPSHALEDEGWAAAAPS(0.741)PGS(0.259)AR;AGPDLPSLPSHALEDEGWAAAAPS(0.986)PGS(0.014)AR;AGPDLPSLPSHALEDEGWAAAAPS(0.998)PGS(0.002)AR 197.08 2.7139e-33 156930800.0 91931.0 99917.0 208030.0 311774.0 267210.0 241490.0 182682.0 253926.0 181835.0 219418.0 True False 121163.14571641154 132213.21626657093 205271.38627561255 239899.32116028323 230112.50388034145 226389.59212454132 198940.34409807294 214687.57133899262 191446.42687649024 211736.24260564146 0.5722362134388007 0.6244241167196771 0.9694674078916679 1.1330101932860661 1.0867884545817967 1.0692056746571805 0.9395668008929351 1.013938703629723 0.9041741013278441 1.0 17.69190870907387 -5.269269128654959 3.785451479071246 1.0247824198691373 0.5833191578547315 0.8736950816551988 0.06365334262292029 0.0711292621112598 2.3117893844072204 0.018218744816312547 0.04778891996625198 5.379363245691363e-06 5.269269128654959 -0.4414632620144058 AGPDLPSLPSHALEDEGWAAAAPS(ph)PGSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 AGPDLPSLPSHALEDEGWAAAAPSPGSAR 29 0 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 AGPDLPSLPSHALEDEGWAAAAPS(0.797)PGS(0.203)AR;AGPDLPSLPSHALEDEGWAAAAPS(0.968)PGS(0.032)AR;AGPDLPSLPSHALEDEGWAAAAPS(0.99)PGS(0.01)AR;AGPDLPSLPSHALEDEGWAAAAPS(0.651)PGS(0.349)AR;AGPDLPSLPSHALEDEGWAAAAPS(0.997)PGS(0.003)AR;AGPDLPSLPSHALEDEGWAAAAPS(0.912)PGS(0.088)AR 209.73 6.6122e-40 132565700.0 165649.0 225546.0 322265.0 348732.0 390951.0 356797.0 315642.0 305187.0 318051.0 257881.0 True False 193690.10398311695 247936.7162984144 329949.019796818 329193.6766443987 314346.95801523654 338085.93721477926 285742.1047098152 297176.1646223557 322701.8941816227 304632.7839151269 0.6358150343959057 0.8138871762649534 1.0831041083508082 1.080624588114307 1.031888144064022 1.1098146853064004 0.9379886860418318 0.9755225974140437 1.0593143982544242 1.0 18.216711684307562 -5.023005988283316 2.9667140621342623 1.0342944258420526 0.6413595820228088 0.8631537256815802 0.051566543932885026 0.0966436748500672 1.6034291086017387 0.014481781622635605 0.0688186034391131 9.48405386092823e-06 5.023005988283316 -0.3929348438192437 AGPDLPSLPSHALEDEGWAAAAPS(ph)PGSAR ddPTM_PC-9_Lapatinib_30min_R1 4 AGPDLPSLPSHALEDEGWAAAAPSPGSAR 29 0 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 AGPDLPSLPSHALEDEGWAAAAPS(0.934)PGS(0.066)AR;AGPDLPSLPSHALEDEGWAAAAPS(0.89)PGS(0.11)AR;AGPDLPSLPSHALEDEGWAAAAPS(0.94)PGS(0.06)AR;AGPDLPSLPSHALEDEGWAAAAPS(0.946)PGS(0.054)AR 213.37 1.0484e-46 121167000.0 183306.0 154978.0 219947.0 181336.0 176072.0 183805.0 147459.0 150168.0 222255.0 131988.0 True False 180692.0228257962 154619.15796281985 201863.80667997227 194672.0543591633 165715.79113087087 175944.08862038207 155093.7054975718 157145.35349523666 197222.3014510932 154801.94993704473 1.1672464261547124 0.9988191881672084 1.3040133329203332 1.2575555697995604 1.0705019620118779 1.1365754029063295 1.001884702102562 1.0151380751931416 1.274029826699858 1.0 17.240064118701994 -6.293286891195057 24.51391889492679 1.082399388614116 1.177552597407703 0.172712358500972 0.10584886425120814 1022.4938610789152 787038.7771239704 0.03360008067374506 0.038102753946971386 5.089945225762848e-07 6.293286891195057 0.09515320879358691 AGPGS(ph)SPLFSLLPGYR ddPTM_PC-9_AZD4547_30min_R2 1 AGPGSSPLFSLLPGYR 16 0 Q9H0W8-2;Q9H0W8 Q9H0W8-2 SMG9 Protein SMG9 1 AGPGS(0.935)S(0.065)PLFSLLPGYR 278.62 1.4164999999999998e-82 5391100.0 11565.0 8663.8 13834.0 19303.0 15929.0 16462.0 10765.0 17175.0 13484.0 14197.0 True False 15242.42943305633 11464.203920156904 13650.552121024974 14852.991578377103 13717.533304554296 15432.628537638016 11723.064145431712 14520.998392237125 14196.736711868409 13699.967351230485 1.1125887414386653 0.8368052000596358 0.9963930402942841 1.0841625529160883 1.0012821894296144 1.1264719208438048 0.8557001520429744 1.0599294158852792 1.036260623686326 1.0 13.741884834613062 -5.517941439394519 24.951605949692443 1.0236676882196298 0.9601725116840586 0.04029970699470886 0.09133805215686949 521.729450667981 2636656.116038025 0.02346303999946491 0.04213522273711169 3.034300304021935e-06 5.517941439394519 -0.06349517653557124 AGPGS(ph)SPLFSLLPGYR ddPTM_PC-9_Lapatinib_30min_R1 1 AGPGSSPLFSLLPGYR 16 0 Q9H0W8-2;Q9H0W8 Q9H0W8-2 SMG9 Protein SMG9 1 AGPGS(0.5)S(0.5)PLFSLLPGYR 222.75 6.172399999999999e-24 7721200.0 23891.0 24664.0 27912.0 19605.0 25743.0 23589.0 22924.0 23332.0 34482.0 19912.0 True False 23550.30995892719 24606.892023351633 25617.1831034358 21046.817100362812 24228.847352685312 22580.153458644734 24110.89255200655 24416.089897653674 30598.274048442545 23353.762668927764 1.008416086640331 1.053658563383928 1.0969188762682565 0.9012173926202329 1.0374708219897195 0.9668743225128207 1.032420038424307 1.0454884826820365 1.3102074591668957 1.0 14.511367389719029 -8.024069993203813 24.400231840142766 1.162685203103668 1.0151777279546972 0.29874788821957654 0.08517737814584594 616.7732815953211 625230.496351495 0.05287763057683574 0.020250135717186517 9.460846730507568e-09 8.024069993203813 -0.1475074751489709 AGPGSS(ph)PLFSLLPGYR ddPTM_PC-9_Lapatinib_30min_R1 1 AGPGSSPLFSLLPGYR 16 0 Q9H0W8-2;Q9H0W8 Q9H0W8-2 SMG9 Protein SMG9 1 AGPGS(0.046)S(0.924)PLFS(0.03)LLPGYR 97.20299999999999 0.0022202 9598900.0 21975.0 25937.0 28942.0 29966.0 29822.0 24085.0 25558.0 21391.0 32346.0 25596.0 True False 21661.63247027854 25876.944470064525 26562.50047935079 32169.79960364557 28067.92859230785 23054.940694877205 26881.26818374557 22384.903951684795 28702.852861519703 30020.234495473862 0.7215677303768048 0.8619834223468834 0.884819886512066 1.071603874663131 0.9349670002257857 0.7679800335454804 0.8954383147073168 0.7456605295691398 0.9561168772964521 1.0 14.873647625799721 -12.967105492123233 0.8723384717480943 3.311318509062505 0.8729761147499431 0.1287556222391717 0.1005518277372339 37821.27502120817 543.9994059758485 171416.48295198556 0.03359299719999159 1.0786846729459944e-13 12.967105492123233 -2.4383423943125617 AGPGTLSVTIEGPSK ddPTM_PC-9_Lapatinib_30min_R1 1 AGPGTLSVTIEGPSK 15 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7 O75369-2 FLNB Filamin-B 0 160.18 0.0012867 2666900.0 6936.2 7549.9 11045.0 7195.9 7599.2 9814.0 8124.6 5029.7 8985.8 6886.8 False True 6837.288516056704 7532.418670414473 10136.922734932949 7725.110490818704 7152.229996602037 9394.27809755138 8545.252034026887 5263.398223822585 7973.724579331104 8077.174203915818 0.8464951161684717 0.9325561737621992 1.2550085560886584 0.956412514549156 0.8854866585809964 1.1630649358778258 1.0579506914539674 0.6516385670214823 0.987192349456254 1.0 12.979634939639055 AGPPAPAPPAPIPPPAPS(ph)QSSPPEQPQSMEMR ddPTM_PC-9_AZD4547_30min_R2 2 AGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMR 32 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 AGPPAPAPPAPIPPPAPS(0.329)QS(0.329)S(0.329)PPEQPQS(0.012)MEMR;AGPPAPAPPAPIPPPAPS(0.41)QS(0.292)S(0.292)PPEQPQS(0.005)MEMR 68.024 2.6041e-05 11300300.0 38777.0 36965.0 59555.0 81049.0 64014.0 54037.0 49235.0 66626.0 44246.0 52036.0 True False 51107.27938829446 48913.21336002674 58765.26178745427 62364.405244567446 55126.76106207161 50658.05784767015 53616.819619166774 56330.4826131698 46584.75323000074 50214.23547852571 1.0177846760238072 0.9740905720041211 1.170290879218612 1.241966638548899 1.0978313328228755 1.0088385766489314 1.0677613451288368 1.121803051990301 0.9277200536075644 1.0 15.615808798364283 -6.692177620368837 7.5716610321137265 1.0356054252489926 1.1055619533394678 0.16162478691794024 0.08361153167414666 0.5425116007784904 50.644630503139915 0.030193546063765005 0.03009385334916298 2.0315259752968773e-07 6.692177620368837 0.06995652809047526 AGPPAPAPPAPIPPPAPS(ph)QSSPPEQPQSMEMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMR 32 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 AGPPAPAPPAPIPPPAPS(0.33)QS(0.33)S(0.33)PPEQPQS(0.01)MEMR 53.097 0.0017870999999999998 5700000.0 13433.0 9464.4 13394.0 13127.0 17650.0 11947.0 11307.0 13860.0 14513.0 9394.0 True False 15706.941586156343 10403.963083959447 13713.363757027864 12391.536748308206 14191.609201585132 11320.478288508488 10235.919104409038 13496.189685883883 14725.22516910148 11097.05783713691 1.4154149520237882 0.9375424762716849 1.2357657280234535 1.1166506411131112 1.2788623263809742 1.0201333051201995 0.9223993651861465 1.2161953090591406 1.3269485826975427 1.0 13.437889605096585 -6.769860938864176 24.999581478001918 1.0997265461194674 1.1801481835089613 0.08760646778457792 0.15620434362576124 631.3670084935513 1874217.3181595188 0.0548779084726064 0.04919501644894086 1.6987875173144493e-07 6.769860938864176 0.08042163738949393 AGPSAQEPGS(ph)QTPLK ddPTM_PC-9_Lapatinib_30min_R1 1 AGPSAQEPGSQTPLK 15 0 O60271;A0A087X2D8;O60271-4;O60271-2;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 AGPS(0.002)AQEPGS(0.778)QT(0.22)PLK 139.34 6.0274e-05 7108000.0 31723.0 33472.0 35734.0 32910.0 40148.0 36840.0 27834.0 31393.0 35836.0 32383.0 True False 31270.624202714287 33394.49764051356 32796.08845722899 35330.311184541686 37786.57357400494 35264.439078234456 29275.108327192036 32851.63338578098 31799.77231019047 37980.358402364815 0.8233367329352861 0.8792570435152681 0.8635012895293522 0.9302258501684353 0.9948977619877382 0.9284914772167802 0.7707959997915461 0.8649637541002115 0.8372688844402922 1.0 15.212965899119922 -7.107839680906352 0.00747815609567578 1.7776522401947599 2.872122946300086e-06 0.09995915862888727 0.066461186157018 13848.249688125621 53.634363676016754 6281.097065121664 6463.992435766517 7.80118036666321e-08 7.107839680906352 -1.7776493680718135 AGPSAQEPGSQT(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 2 AGPSAQEPGSQTPLK 15 0 O60271;A0A087X2D8;O60271-4;O60271-2;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 AGPS(0.004)AQEPGS(0.015)QT(0.981)PLK;AGPSAQEPGS(0.416)QT(0.584)PLK 165.24 0.00030407 11957500.0 41172.0 38555.0 51684.0 57060.0 58990.0 59009.0 45825.0 58407.0 46100.0 50925.0 True False 54263.83956919978 51017.1497658821 50998.6363902743 43905.69856821204 50800.25674151915 55319.15790168156 49903.33622521204 49381.540209338775 48536.75188498468 49142.131250363615 1.1042223482889393 1.0381550101269694 1.037778278895809 0.8934431098343374 1.0337414240889942 1.1256971664466067 1.0154898649179525 1.0048717658938202 0.9876810518800108 1.0 15.584672807002377 -4.7701223531230195 2.1461048019738773 1.0136516322601612 1.129693444337436 0.21172233441165134 0.05374346369340797 1.2471776896691218 6.409457317308183 0.015315592803674491 0.2863229624258533 1.697765276252978e-05 4.7701223531230195 0.11604181207727482 AGPSAQEPGSQT(ph)PLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGPSAQEPGSQTPLK 15 0 O60271;A0A087X2D8;O60271-4;O60271-2;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 AGPSAQEPGS(0.088)QT(0.912)PLK;AGPSAQEPGS(0.002)QT(0.998)PLK 138.98 5.7189e-05 9949900.0 41051.0 42048.0 43971.0 56217.0 50894.0 42980.0 48300.0 43168.0 44641.0 39637.0 True False 48000.12350579198 46222.24755444895 45019.435400946124 53067.34374797311 40921.68604563591 40726.053138034236 43724.67433828216 42034.88574027675 45293.79017252528 46822.874333680644 1.0251426079424713 0.9871723641963678 0.9614838055459302 1.1333636497791997 0.8739678336278496 0.8697896854388361 0.9338314864371774 0.8977425315822657 0.9673432230952241 1.0 15.514925879989638 -6.291302865170032 24.997555107366324 0.9164693977793043 1.019296011313767 0.4407475700810398 0.056234178100143015 641.8233720680525 537243.2787515464 0.017151795133688332 0.01945080415337314 5.113251269267001e-07 6.291302865170032 0.10282661353446276 AGPSFS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGPSFSK 7 0 A0A0A6YYA4;Q96M83 A0A0A6YYA4 CCDC7 Coiled-coil domain-containing protein 7 1 AGPS(0.003)FS(0.997)K 69.628 0.046066 4126600.0 48566.0 54233.0 51535.0 65084.0 73637.0 52454.0 61232.0 56878.0 50381.0 46915.0 True False 56787.264577776325 59616.89382658936 52763.78984757586 61437.55448517498 59208.358457627415 49703.2199000104 55431.66167871006 55385.01276722248 51117.726813512156 55420.31812106431 1.0246650777739303 1.075722692467368 0.9520658061239323 1.1085745547502301 1.0683511113791917 0.8968411150480037 1.0002046822903645 0.9993629528837292 0.9223643700825886 1.0 15.758127371681747 -6.7382163409354 24.999990099136443 0.9659929043703721 1.0458056127445552 0.40528384214781576 0.04970238450685848 247.56462013164955 266506.9473245095 0.0161723561276716 0.01616282934538511 1.8271897868430342e-07 6.7382163409354 0.07981270837418308 AGPSFS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 AGPSFSK 7 0 A0A0A6YYA4;Q96M83 A0A0A6YYA4 CCDC7 Coiled-coil domain-containing protein 7 1 AGPS(0.001)FS(0.999)K 69.628 0.046066 3478800.0 33444.0 48334.0 57497.0 42372.0 56396.0 61936.0 52919.0 56886.0 71330.0 44666.0 True False 32967.08242712154 48222.08559263213 52769.81860483837 45488.1782288484 53078.898158801996 59287.14165986778 55658.886885344386 59529.13123255295 63296.064261800595 52386.45858629611 0.6293054219882974 0.9205066899721038 1.0073179220143456 0.8683193988751085 1.0132179114830835 1.1317264663387046 1.0624670647216514 1.1363457816964422 1.208252398996071 1.0 15.676906316214199 -4.019937086852306 0.47561060426356033 1.1165532562241836 8.440379311637728e-12 0.7260499763428113 0.0818357820234091 5.2078487547705885 0.5256987045207677 0.053115455480055175 3.7960997090543582 9.551309390149013e-05 4.019937086852306 -1.1165532562157432 AGPVS(ph)PGCVK ddPTM_PC-9_Lapatinib_30min_R1 1 AGPVSPGCVK 10 0 E9PPE7;E9PK67;E9PNI7;Q53GL7 E9PPE7 PARP10 Poly [ADP-ribose] polymerase 10 1 AGPVS(1)PGCVK 104.07 0.0026576 9593400.0 39012.0 92117.0 64175.0 55096.0 56893.0 59507.0 74576.0 64098.0 83783.0 64252.0 True False 38455.68172607542 91903.70874615163 58898.77922266383 59147.943634868105 53546.66559594161 56962.02432759224 78437.18037682946 67076.22708125353 74346.47626589704 75357.87258959167 0.5103074224973128 1.2195634721095516 0.7815876058953242 0.7848940210533164 0.7105649848631396 0.7558868419470185 1.0408624564550553 0.8901024508289795 0.9865787569508123 1.0 16.201470616690052 -7.257513865816064 24.866007437843827 0.9702277872538605 0.8084101412912471 0.22196360432758722 0.1685467880710066 570.1051964271603 3611321.168294295 0.0648696016601297 0.048322379879735686 5.526957616228056e-08 7.257513865816064 -0.1618176459626134 AGQAVDDFIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGQAVDDFIEK 11 0 P52209-2;P52209;K7EMN2;K7EM49;K7EPF6 P52209-2 PGD 6-phosphogluconate dehydrogenase, decarboxylating 0 165.63 0.008407099999999999 2494900.0 14174.0 17801.0 14763.0 22612.0 23591.0 17479.0 15780.0 19557.0 14640.0 14970.0 False True 16573.37825073923 19568.16563728943 15115.005908989284 21345.12294909311 18968.51289941048 16562.37046997907 14285.20416269344 19043.649472354333 14854.082303841085 17683.942497545213 0.9371992842116432 1.1065499472193925 0.8547305506725927 1.2070341753291791 1.0726404986921658 0.9365768109842115 0.8078065264392504 1.0768893573928928 0.8399757184181664 1.0 14.110152327784578 -6.789545864479794 12.222880589327852 0.9292340411566377 1.0390365423784427 0.17233659163907344 0.11305988595840116 1.5401170094606391 665.3234469756004 0.03851092953994668 0.03414541849641955 1.623506887952035e-07 6.789545864479794 0.10980250122180502 AGQAVDDFIEK ddPTM_PC-9_Lapatinib_30min_R1 4 AGQAVDDFIEK 11 0 P52209-2;P52209;K7EMN2;K7EM49;K7EPF6 P52209-2 PGD 6-phosphogluconate dehydrogenase, decarboxylating 0 ;;; 194.5 0.00066641 53694000.0 253750.0 237969.0 257203.0 244411.0 268854.0 213973.0 256327.0 229368.0 244506.0 238342.0 False True 250131.47846794938 237417.9974012717 236056.76217229184 262385.80027119524 253040.5363073011 204821.87358542506 269598.3578423566 240025.27462905116 216967.15951767546 279539.09712924814 0.8947996220804069 0.8493194685089033 0.8444498984095533 0.9386372173545303 0.9052062445143582 0.73271279648844 0.9644388230877939 0.8586465259922933 0.7761603358737263 1.0 18.092690551028703 -10.726914793281674 4.9477358712212824 1.00001564334665 0.8643095226847745 0.27848601498115455 0.0662509052203122 93061600.13766909 1.4632588988896147 16585.292107241945 0.015676941667064584 1.8753624100530932e-11 10.726914793281674 -0.1357061206618756 AGQEPS(ph)PKPGTDVIPAAPR ddPTM_PC-9_AZD4547_30min_R2 2 AGQEPSPKPGTDVIPAAPR 19 1 Q4VC44-2;Q4VC44;Q4VC44-3;I3L0R3;I3L231 Q4VC44-2 FLYWCH1 FLYWCH-type zinc finger-containing protein 1 1 AGQEPS(0.91)PKPGT(0.09)DVIPAAPR;AGQEPS(0.983)PKPGT(0.017)DVIPAAPR 72.92699999999999 0.002479 53221000.0 62335.0 39444.0 58086.0 68320.0 58497.0 59056.0 51925.0 57522.0 56990.0 51537.0 True False 82156.23335145407 52193.501630539584 57315.74168728182 52569.87953347786 50375.70128171971 55363.21898425171 56546.22440794624 48633.29662406194 60002.375052609095 49732.70531664194 1.651955847331762 1.0494804434673333 1.1524758470780874 1.0570484593341944 1.0129290365562036 1.1132155114378153 1.1370027841422152 0.9778936479409234 1.2064973073670826 1.0 15.601907291300357 -4.759563139388305 24.99937651873972 1.0803185460359375 1.6519565670585268 0.8594407674355916 0.06956929176029959 15.783037686632 210239.08525195817 0.016101716640102973 0.10139813083729426 1.7395497772716687e-05 4.759563139388305 0.5716380210225893 AGQEPS(ph)PKPGTDVIPAAPR ddPTM_PC-9_Lapatinib_30min_R1 2 AGQEPSPKPGTDVIPAAPR 19 1 Q4VC44-2;Q4VC44;Q4VC44-3;I3L0R3;I3L231 Q4VC44-2 FLYWCH1 FLYWCH-type zinc finger-containing protein 1 1 AGQEPS(0.995)PKPGT(0.005)DVIPAAPR;AGQEPS(0.668)PKPGT(0.332)DVIPAAPR 82.87700000000001 0.00080867 51105000.0 64190.0 63941.0 61178.0 72154.0 68832.0 73591.0 71199.0 58875.0 62951.0 56652.0 True False 63274.638828995696 63792.94854302335 56148.180993909256 77460.44585868782 64783.43708891868 70443.68447899984 74885.33584061735 61610.54743375451 55860.79547658217 66444.2227159551 0.9522970732834188 0.9600977471846457 0.8450423332354903 1.16579655374744 0.9750048151795504 1.0601927692064697 1.127040588024447 0.9272521359326567 0.840717118708478 1.0 16.019856143063144 -5.725392236451434 24.99983133280212 1.0157296964641704 0.9232410496796353 0.17936114146987459 0.09250329634229167 330.36768614031405 229118.08025482504 0.026007176215251292 0.04504399875129049 1.881948625120285e-06 5.725392236451434 -0.09248864678453517 AGQHS(ph)PLR ddPTM_PC-9_Lapatinib_30min_R1 1 AGQHSPLR 8 0 Q9H4L4;A0A087X0R7 Q9H4L4 SENP3;SENP3-EIF4A1 Sentrin-specific protease 3 1 AGQHS(1)PLR 80.916 0.010553 6083200.0 27034.0 44335.0 21170.0 21189.0 37402.0 26827.0 48022.0 49222.0 31821.0 30387.0 True False 26648.490202571575 44232.3450314343 19429.484318563205 22747.309744431903 35202.08789516124 25679.671746791417 50508.34418654937 51509.03381374543 28236.983890014806 35639.352461867624 0.7477265539850693 1.2411096716406607 0.5451693977703946 0.6382638340236518 0.9877308498471111 0.7205426017284522 1.4172071235186119 1.445285344868642 0.7922978937461619 1.0 15.121183504048478 -7.2503295236047505 24.710725373478887 1.2008047084969247 0.8206319217375686 0.3098211126909882 0.25357357737737435 725.2212343422418 1613051.6424569222 0.09775421966711632 0.07497359904755471 5.619148070891123e-08 7.2503295236047505 -0.38017278675935606 AGQTQPNPGILPIQPALT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 AGQTQPNPGILPIQPALTPR 20 0 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 1 AGQTQPNPGILPIQPALT(1)PR;AGQTQPNPGILPIQPALT(1)PR;AGQTQPNPGILPIQPALT(1)PR 148.19 0.00012739 29438900.0 76863.0 80306.0 103063.0 137311.0 149352.0 133430.0 102937.0 153804.0 96605.0 120299.0 True False 101303.83515028178 106263.34403057785 101696.3172798321 105656.07038380246 128617.05280317595 125086.60100698828 112098.19358460806 130037.12586431643 101711.34307698379 116087.36862616565 0.8726516618402209 0.9153738713190755 0.8760325820401974 0.9101426936813863 1.107933225856462 1.0775212022403808 0.9656364418561 1.1201660215339446 0.8761620172865081 1.0 16.82485147668524 -6.130889763253517 6.564484650491975 1.0299683461052551 0.8913005040891336 0.470949989125912 0.06811101945478194 0.2047607844995948 10.041457681625685 0.019290413252488467 0.025049513410077395 7.397930325155614e-07 6.130889763253517 -0.13866784201612148 AGQTQPNPGILPIQPALT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AGQTQPNPGILPIQPALTPR 20 0 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 1 AGQTQPNPGILPIQPALT(1)PR;AGQTQPNPGILPIQPALT(1)PR;AGQTQPNPGILPIQPALT(1)PR 180.16 2.537e-09 19841100.0 77289.4 79625.6 102319.6 105618.4 133168.0 117420.0 95183.0 101787.0 100177.0 89893.8 True False 90372.96888476684 87530.30334074207 104759.28731324368 99700.94346747285 107074.68635448656 111262.28849390362 86166.577174756 99115.19910224124 101641.89910873577 106190.8343410706 0.8510430249987592 0.824273619129939 0.986519109330764 0.9388846418443885 1.0083232420095425 1.0477579273607003 0.8114313980997702 0.9333686821208752 0.957162637806157 1.0 16.69629972248719 -5.25661669940065 24.86706250687764 0.956789601075518 0.8376583090575968 0.3998524992295599 0.06003208448426417 394.11923815847996 2032168.0150977876 0.016072059889921404 0.0397391910633587 5.53838701777908e-06 5.25661669940065 -0.11913129201792128 AGQTQPNPGILPIQPALT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 AGQTQPNPGILPIQPALTPR 20 0 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 1 AGQTQPNPGILPIQPALT(1)PR;AGQTQPNPGILPIQPALT(1)PR 149.18 0.00030542 22183000.0 127148.0 100054.0 122778.0 102832.0 103123.0 91587.0 68634.0 68691.0 102700.0 76841.0 True False 125334.84620391237 99822.33111029949 112683.66677678577 110394.60831749592 97057.50788761857 87670.03750972479 72187.53269125888 71882.63462882423 91132.84452105581 90122.8644658036 1.3907108584134014 1.107624926282456 1.2503338353114894 1.2249345265693843 1.0769465491683996 0.9727835220216561 0.8009902161803774 0.7976070784578704 1.0112067016648747 1.0 16.459605548481584 -6.598946827287699 1.8513949401222811 0.8867253277079046 1.2376312124960795 0.7325881194193855 0.09319180811841157 0.17131862009717516 1.199013203109719 0.03550075062245177 0.0365466025006008 2.5179851976359315e-07 6.598946827287699 0.35090588478817497 AGRLEEQLGR ddPTM_PC-9_Lapatinib_30min_R1 1 AGRLEEQLGR 10 1 A9Z1Z3-3;A9Z1Z3 A9Z1Z3-3 FER1L4 Fer-1-like protein 4 0 82.831 0.018635 2503200.0 12651.0 11293.0 10929.0 9901.8 10095.0 11141.0 10667.0 10604.0 11456.0 10132.0 False True 12470.594420090743 11266.851752339855 10030.459807160001 10630.011403436487 9501.231947533632 10664.525400939472 11219.28506596815 11096.700551805225 10165.704642971921 11883.30269995863 1.0494215905258526 0.9481246112142779 0.844080140043468 0.8945334198609192 0.7995447214827499 0.8974378310649782 0.9441217941883454 0.9338061002051102 0.8554612214841008 1.0 13.536648236450494 -4.869532289048701 3.213117915329801 0.8920050069349238 1.057920772275931 0.4304669705155687 0.053468833512581984 0.26301230586765506 4.521471354380957 0.013620069502313606 0.09770485800139628 1.3504164229813095e-05 4.869532289048701 0.16591576534100716 AGS(ph)EECVFYTDETASPLAPDLAK ddPTM_PC-9_Lapatinib_30min_R1 2 AGSEECVFYTDETASPLAPDLAK 23 0 A0A087WXN9;Q765P7 A0A087WXN9 MTSS1L MTSS1-like protein 1 AGS(1)EECVFYTDETASPLAPDLAK;AGS(0.998)EECVFY(0.002)TDETASPLAPDLAK 118.9 2.5406e-05 0.0 14435.5 16037.8 18765.0 21055.8 22059.3 19070.3 16064.599999999999 15919.2 18010.8 16353.9 True False 14229.647122853512 16000.665459459502 17222.214134994734 22604.313772089714 20761.815344252456 18254.70772404056 16896.34638330851 16658.864147896813 15982.234041867894 19180.649824798 0.7418751321165611 0.8342087262743723 0.897895237768677 1.1784957224371708 1.082435451035148 0.9517251965279965 0.8809058367492746 0.8685244921347316 0.8332477881539245 1.0 14.227363978066728 -5.207505269284146 2.700789358474202 0.9680006924431195 0.7635611157825108 0.35086767398430396 0.09913971411240526 0.3641100317354048 5.06919934957921 0.03045979053515584 0.10608855546742246 6.201471193785656e-06 5.207505269284146 -0.20443957666060864 AGS(ph)FTGTSDPEAAPAR ddPTM_PC-9_Lapatinib_30min_R1 2 AGSFTGTSDPEAAPAR 16 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 AGS(0.972)FT(0.019)GT(0.003)S(0.005)DPEAAPAR;AGS(0.995)FTGT(0.002)S(0.002)DPEAAPAR 143.64 1.9131e-05 6652800.0 21781.6 23256.0 28882.0 22951.0 31004.0 29596.0 24858.0 27508.0 33272.0 25818.0 True False 21470.990389743754 23202.15216084437 26507.433447744075 24638.893102291597 29180.40567620926 28330.24807164569 26145.02560887188 28786.122102891193 29524.556990307407 30280.606899677445 0.7090673730840074 0.7662380162232324 0.8753930704085867 0.8136855771723008 0.9636664738222303 0.9355904974265052 0.86342475550417 0.9506454807283875 0.9750318772713208 1.0 14.88610650040746 -3.165823887532932 0.3235192349804401 0.9748297195457498 1.4537491264643785e-13 0.8119578262095573 0.04000001443577562 8.731200382255432 0.32167604983620385 0.039513346566582015 4.104828848103826 0.0006826154481048768 3.165823887532932 -0.9748297195456045 AGS(ph)ISTLDSLDFAR ddPTM_PC-9_AZD4547_30min_R2 2 AGSISTLDSLDFAR 14 0 A0A075B785;A0A2R8Y566;Q9P260;Q9P260-2 A0A075B785 KIAA1468 LisH domain and HEAT repeat-containing protein KIAA1468 1 AGS(1)ISTLDSLDFAR;AGS(0.916)IS(0.08)T(0.004)LDSLDFAR 174.46 0.0001298 20182200.0 18954.2 17509.7 23481.8 27744.0 24218.0 20547.0 15272.099999999999 20088.5 16313.0 20094.2 True False 24981.24132814841 23169.368104154222 23170.415989264435 21348.049440527073 20855.748733109165 19262.19284186906 16631.287314022073 16984.283912806728 17175.271876350434 19390.70817419846 1.2883099009962304 1.1948696198204716 1.1949236604001554 1.1009422270060811 1.0755537418102197 0.9933723239411955 0.8576936522695902 0.8758980724286413 0.885747530314756 1.0 14.243077873079118 -6.353363716998951 0.8777335447638035 0.8903222425251003 1.2482089241706562 0.8852613739359583 0.04813099265174318 0.18317781082619652 0.3061797615573986 0.02534617383198052 0.03730286434811246 4.432372819486302e-07 6.353363716998951 0.3578866816455559 AGS(ph)ISTLDSLDFAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AGSISTLDSLDFAR 14 0 A0A075B785;A0A2R8Y566;Q9P260;Q9P260-2 A0A075B785 KIAA1468 LisH domain and HEAT repeat-containing protein KIAA1468 1 AGS(0.912)IS(0.074)T(0.015)LDSLDFAR;AGS(0.967)IS(0.016)T(0.016)LDSLDFAR;AGS(1)ISTLDSLDFAR;AGS(0.943)IS(0.028)T(0.028)LDSLDFAR 154.72 0.00030391 16924500.0 39154.9 46927.8 41295.6 44828.5 48836.4 42931.600000000006 47054.7 49046.5 40834.6 34944.6 True False 45783.05122547404 51586.48184897423 42280.243718435115 42316.90448095795 39267.25799503073 40680.191319237594 42597.33816947342 47759.08134406235 41431.72877352661 41279.77935869861 1.109091471338654 1.249679204937508 1.0242361847684074 1.0251242893826369 0.9512467994031613 0.9854750183073673 1.0319177774504547 1.156960673870424 1.0036809648013776 1.0 15.33314763909545 -5.278554043531006 24.730316826303568 1.0245231927037026 1.179385330899656 0.5268616749306458 0.05950398599097101 494.663988629935 714778.4444338718 0.016253667807828744 0.03398339837454607 5.265576860684409e-06 5.278554043531006 0.1548621381959534 AGS(ph)ISTLDSLDFAR ddPTM_PC-9_Lapatinib_30min_R1 1 AGSISTLDSLDFAR 14 0 A0A075B785;A0A2R8Y566;Q9P260;Q9P260-2 A0A075B785 KIAA1468 LisH domain and HEAT repeat-containing protein KIAA1468 1 AGS(0.851)IS(0.121)T(0.028)LDSLDFAR 188.12 3.8407e-06 8405200.0 16015.0 11775.0 15274.0 12919.0 18640.0 17000.0 13499.0 14807.0 15912.0 14400.0 True False 15786.623163208682 11747.73571095384 14018.230679345039 13869.106356520639 17543.631847650013 16272.949628935545 14197.912168885732 15494.98727561108 14119.822999211698 16889.02081320611 0.9347269648021617 0.6955841810419158 0.8300203329954866 0.8211906723257695 1.038759561118667 0.9635223858692367 0.8406592854562589 0.9174591852888839 0.8360356207371668 1.0 14.04379806595503 -6.041194445477013 24.208010161767394 0.9259500085623077 0.8106490925368768 0.3171541163318099 0.08003922524839883 409.9684850786503 240918.13903687935 0.02352016546102407 0.030368899683978046 9.095059708456578e-07 6.041194445477013 -0.11530091602543091 AGS(ph)IVLK ddPTM_PC-9_Lapatinib_30min_R1 1 AGSIVLK 7 0 B1ALC0;O15511;O15511-2 B1ALC0 ARPC5 Actin-related protein 2/3 complex subunit 5 1 AGS(1)IVLK 80.219 0.025726 3219400.0 31631.0 28986.0 33415.0 29024.0 35372.0 29469.0 27434.0 24591.0 28610.0 22941.0 True False 31179.936139585017 28918.884697894522 30667.747685630125 31158.52178122571 33291.48850402769 28208.679565594233 28854.39828440706 25733.587633859133 25387.640523343816 26906.321283038957 1.1588331162625356 1.0747989066838444 1.1397971265942726 1.1580372304878122 1.23731104500762 1.048403431626911 1.0724022054473912 0.956414195874518 0.94355672989557 1.0 14.715657534202506 -7.405259657416549 1.6512221948361019 0.9622314731118331 1.1452377114506544 0.7183296966774961 0.0480561826691112 0.2090496203156729 1.1069898916634446 0.029970799410113703 0.016145266677408076 3.933148487653364e-08 7.405259657416549 0.18300623833882135 AGS(ph)LGPETPSR ddPTM_PC-9_AZD4547_30min_R2 1 AGSLGPETPSR 11 0 F8W9F9;H0Y7T5;Q9Y3S1-2;Q9Y3S1-4;Q9Y3S1;H0Y7R3;H0Y7J9;H0Y493 F8W9F9 WNK2 Serine/threonine-protein kinase WNK2 1 AGS(1)LGPETPSR 107.97 0.0022438000000000002 9999900.0 20842.0 20117.0 27630.0 41332.0 39924.0 32567.0 29557.0 39319.0 23666.0 32606.0 True False 27469.322459469084 26619.426840623793 27263.608146878712 31803.545973034357 34381.24173840327 30530.580341711655 32187.51574050395 33243.152010734884 24916.936444903436 31464.47386449399 0.8730265943034495 0.8460153173151395 0.866488607573517 1.0107763476357694 1.0927003542621032 0.970319112062567 1.0229796270906621 1.0565297279052246 0.791906979033293 1.0 14.941436198530235 -5.756246173236795 21.700822251246674 0.9990902519877777 0.8602604056152237 0.38293454963442686 0.07545039217758556 23.927170726293706 99974.83721305837 0.02038608602270925 0.033832940376979335 1.7528866230030172e-06 5.756246173236795 -0.13882984637255402 AGS(ph)LGPETPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGSLGPETPSR 11 0 F8W9F9;H0Y7T5;Q9Y3S1-2;Q9Y3S1-4;Q9Y3S1;H0Y7R3;H0Y7J9;H0Y493 F8W9F9 WNK2 Serine/threonine-protein kinase WNK2 1 AGS(0.99)LGPET(0.009)PS(0.001)R;AGS(0.833)LGPET(0.083)PS(0.083)R 91.09299999999999 0.00838 19549100.0 58440.0 64234.0 78828.0 87287.0 90184.0 90720.0 79504.0 78402.0 79250.0 67356.0 True False 68332.73775738689 70610.72701228285 80707.55847685496 82396.59237827217 72513.09259126075 85962.48349656741 71972.80556088586 76344.03057378542 80408.88132372995 79567.10961019756 0.8588063345790955 0.8874361197510833 1.0143331694747304 1.0355609595715662 0.9113450638901587 1.0803771045310184 0.9045547326462341 0.959492319726051 1.0105793928880447 1.0 16.279884571521897 -5.164167210943925 4.885478736342434 0.986993915942505 0.866676009875535 0.4562195639554981 0.05101899763201625 0.1921112678810612 7.314335844979636 0.012701751235655187 0.03614367191192218 6.852243523408898e-06 5.164167210943925 -0.12031790606697002 AGS(ph)LGPETPSR ddPTM_PC-9_Lapatinib_30min_R1 1 AGSLGPETPSR 11 0 F8W9F9;H0Y7T5;Q9Y3S1-2;Q9Y3S1-4;Q9Y3S1;H0Y7R3;H0Y7J9;H0Y493 F8W9F9 WNK2 Serine/threonine-protein kinase WNK2 1 AGS(1)LGPETPSR 85.973 0.011170999999999999 6172100.0 85874.0 66067.0 80725.0 69640.0 73793.0 73945.0 60210.0 56553.0 78825.0 76297.0 True False 84649.4210126371 65914.02592064423 74088.1021075114 74761.55791222995 69452.64082262001 70782.54472421408 63327.37919020742 59180.658836876726 69946.8984359516 89484.83479063786 0.9459638743334121 0.736594374620674 0.8279403128010545 0.8354662338835954 0.7761386718220363 0.7910004515270059 0.7076883958982612 0.6613484729042419 0.781662039155596 1.0 16.4493555856564 -6.430788967680227 2.0838639795122496 0.7615305862944107 0.829596955976562 0.02390561447150963 0.09664468887797056 0.8410243114308134 7.230857052598812 0.03322302861277996 0.03819744518879458 3.70860886681376e-07 6.430788967680227 0.0680663696821513 AGS(ph)PAPSNR ddPTM_PC-9_AZD4547_30min_R2 4 AGSPAPSNR 9 0 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 AGS(0.996)PAPS(0.004)NR;AGS(1)PAPSNR;AGS(0.974)PAPS(0.026)NR;AGS(1)PAPSNR 102.53 0.0031473000000000004 25597200.0 110924.0 83569.0 58123.0 61067.0 50260.0 49043.5 41439.600000000006 60974.0 84843.0 112481.0 True False 146195.52463747023 110581.04496913505 57352.25104310645 46988.94662574494 43282.26655075017 45976.80219205749 45127.64412085758 51551.86934313051 89327.62776958264 108543.07442655183 1.3468894759968937 1.0187756847072014 0.5283824080541885 0.4329059857019352 0.3987565929877739 0.4235811675222886 0.4157579316715802 0.47494388394180104 0.822969390184615 1.0 16.727908152400786 -5.071345029421276 2.5023969271215853 0.5197480197147243 1.3474811850713246 0.6372145905271931 0.19262066049054413 0.18435437944842933 2.052987376817736 0.049798543234104424 0.24585124029421485 8.485061033700198e-06 5.071345029421276 0.8277331653566004 AGS(ph)PAPSNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGSPAPSNR 9 0 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 AGS(1)PAPSNR 112.83 0.0021416 5755500.0 5476.6 8844.5 9252.8 5388.7 20230.0 24900.0 7927.2 11945.0 19417.0 28675.0 True False 6403.68021221945 9722.523508735821 9473.421843439406 5086.788609401116 16266.076722270107 23594.20016605519 7176.278228042043 11631.456406773668 19700.936891644964 33873.55050882489 0.18904661944283446 0.287024045684342 0.27967017632153285 0.15016992706672078 0.4801999341058858 0.6965375584088336 0.2118549168966639 0.3433787197401521 0.5816023592363719 1.0 15.047871592629347 -14.522878744338758 0.13943124171943086 3.2541325729304087 0.12075185551933797 0.6766330630851566 0.14556781840297325 89.02798683911153 0.7590874077049339 55.51262808344906 0.9684307787952873 3.0000000065042002e-15 14.522878744338758 -3.133380717411071 AGS(ph)PAPSNR ddPTM_PC-9_Lapatinib_30min_R1 4 AGSPAPSNR 9 0 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 AGS(0.982)PAPS(0.018)NR;AGS(0.971)PAPS(0.029)NR;AGS(0.974)PAPS(0.026)NR;AGS(0.997)PAPS(0.003)NR 102.53 0.0031473000000000004 26648100.0 48045.6 87386.0 52944.2 79409.0 102778.0 47562.9 165400.0 150969.0 91297.0 75365.0 True False 47360.46093351606 87183.66308597967 48591.33224652211 85249.00276065867 96732.80010932263 45528.745641535184 173963.60269158444 157983.57087943092 81014.1704599692 88391.73983244998 0.5358018862768136 0.986332696372305 0.5497270710886435 0.9644453534035138 1.0943647029992107 0.5150791887096771 1.9680979582632867 1.7873114747927237 0.9165355339032216 1.0 16.431623936275223 -7.250840955995741 24.929324803087997 1.483595546907528 0.7969146592062961 0.43925837795609146 0.35263905909536736 603.0580412325963 1418499.020264089 0.1334506419052789 0.10226184807106968 5.6125347635819e-08 7.250840955995741 -0.6866808877012318 AGS(ph)PDVLR ddPTM_PC-9_AZD4547_30min_R2 1 AGSPDVLR 8 0 Q8NDX6 Q8NDX6 ZNF740 Zinc finger protein 740 1 AGS(1)PDVLR 82.645 0.016176 50569000.0 20332.0 20297.0 32833.0 35169.0 32620.0 30361.0 23090.0 38555.0 23463.0 28299.0 True False 26797.153068128075 26857.608320531937 32397.612967298923 27061.33040563353 28091.27606218604 28462.521870442735 25144.965268742966 32597.210655761428 24703.20627933614 27308.260623545237 0.981283774808547 0.9834975830491106 1.1863667706234515 0.9909576731628669 1.0286732080609222 1.0422678420573697 0.920782382128832 1.19367582963728 0.9046056290394777 1.0 14.737049805344316 AGS(ph)PDVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGSPDVLR 8 0 Q8NDX6 Q8NDX6 ZNF740 Zinc finger protein 740 1 AGS(1)PDVLR;AGS(1)PDVLR 91.087 0.008988 70626000.0 119765.0 127655.0 113703.0 155846.0 170411.0 134126.0 153323.0 131558.0 122061.0 108972.0 True False 140038.84903342623 140327.74475749605 116414.11074102903 147114.45387954917 137020.187855599 127092.19644467143 138799.13547760752 128104.74189722304 123845.91120827525 128727.76097812281 1.087868288622108 1.0901125265539626 0.9043434753814565 1.1428339369978724 1.0644183260430164 0.9872943915048026 1.078237781990136 0.9951601808641288 0.9620761696408499 1.0 16.973963688108626 -7.901400712632175 6.055000370238405 0.9803224579885674 1.0480769269415762 0.18784185745041737 0.06213093625479906 0.3540274626766266 18.04963459742772 0.034386171504258246 0.016224111497857453 1.2548715908147374e-08 7.901400712632175 0.06775446895300874 AGS(ph)PDVLR ddPTM_PC-9_Lapatinib_30min_R1 2 AGSPDVLR 8 0 Q8NDX6 Q8NDX6 ZNF740 Zinc finger protein 740 1 AGS(1)PDVLR;AGS(1)PDVLR 91.265 0.011898 46847100.0 88009.0 82389.0 89644.0 71405.0 65408.0 82196.0 72353.0 75006.0 83795.0 57504.0 True False 86753.97552112609 82198.2333324652 82273.81635584711 76656.36190009708 61560.83003707572 78680.66868823451 76099.08431405197 78491.05258286503 74357.1246995315 67443.48978073636 1.2863209748364077 1.218771946702307 1.219892633422814 1.1366013554356755 0.9127764627425777 1.166616213722496 1.1283384736088773 1.1638047324959768 1.1025100412400346 1.0 16.041391568247935 -5.801962005046458 3.6158354763926273 1.0891721372953656 1.2429908440004882 0.4840831199981577 0.07452136619222106 0.21409922120049152 5.793582592027043 0.022074996369361773 0.03623464946079807 1.5777492956045883e-06 5.801962005046458 0.15381870670512265 AGS(ph)PFSPPPSSSSLTGEAAISR ddPTM_PC-9_AZD4547_30min_R2 4 AGSPFSPPPSSSSLTGEAAISR 22 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;A0A087WXJ0;C9J760;Q96JY6-2 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 AGS(0.999)PFS(0.001)PPPSSSSLTGEAAISR;AGS(0.999)PFS(0.001)PPPSSSSLTGEAAISR;AGS(1)PFSPPPSSSSLTGEAAISR;AGS(0.995)PFS(0.005)PPPSSSSLTGEAAISR 233.38 2.6669e-51 123766600.0 113682.0 101583.0 156619.0 208279.0 199574.0 171134.0 165633.0 194597.0 167955.0 177268.0 True False 149830.51126750617 134417.71818616515 154542.1297269633 160263.49442847242 171866.59499799824 160432.96392662745 180374.01612636255 164526.5050442016 176832.7584130717 171061.90127618005 0.8758847537044749 0.7857840768947567 0.9034281074513165 0.9368742731891331 1.0047041083713844 0.9378649642599719 1.0544371059874287 0.9617951385830382 1.0337354904501765 1.0 17.384158954542805 -5.759662422228214 1.5312208368610498 0.9981624621765091 0.8286204088165778 0.7425083782271685 0.03881002702880549 0.18529624955088192 0.8776099548078572 0.011815151255291362 0.026756201224988337 1.739152149142212e-06 5.759662422228214 -0.16954205335993122 AGS(ph)PFSPPPSSSSLTGEAAISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 AGSPFSPPPSSSSLTGEAAISR 22 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;A0A087WXJ0;C9J760;Q96JY6-2 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 AGS(1)PFSPPPSSSSLTGEAAISR;AGS(0.999)PFS(0.001)PPPSSSSLTGEAAISR;AGS(1)PFSPPPSSSSLTGEAAISR;AGS(0.997)PFS(0.002)PPPSSSSLTGEAAISR;AGS(0.992)PFS(0.001)PPPS(0.002)S(0.002)S(0.002)S(0.002)LTGEAAISR;AGS(1)PFSPPPSSSSLTGEAAISR 235.21 2.1430999999999997e-51 118898300.0 168010.4 188345.9 200179.0 245157.3 243092.0 181767.4 179324.2 186898.4 168039.2 133589.3 True False 196451.24236334072 207043.63621731117 204952.02654308485 231421.93129169042 195459.86765052335 172235.19756078 162337.31358122142 181992.515035224 170496.4554010665 157807.98259768286 1.2448751902758641 1.3119972311232833 1.2987430874494572 1.4664779783775554 1.2385930320700604 1.0914225929868075 1.0287015327677413 1.153252909259967 1.080404505491536 1.0 17.26781065927367 -6.652107441993474 3.5826140849105217 1.0765679890124025 1.3293961503360767 0.7819147936310589 0.06499407716335404 0.1111594563022061 2.7543645682122606 0.02274334477266644 0.022498142844938975 2.2278839152328537e-07 6.652107441993474 0.25282816132367425 AGS(ph)PFSPPPSSSSLTGEAAISR ddPTM_PC-9_Lapatinib_30min_R1 5 AGSPFSPPPSSSSLTGEAAISR 22 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;A0A087WXJ0;C9J760;Q96JY6-2 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 AGS(0.999)PFS(0.001)PPPSSSSLTGEAAISR;AGS(0.971)PFS(0.029)PPPSSSSLTGEAAISR;AGS(0.997)PFS(0.003)PPPSSSSLTGEAAISR;AGS(0.565)PFS(0.434)PPPS(0.001)SSSLTGEAAISR;AGS(0.943)PFS(0.057)PPPSSSSLTGEAAISR 181.6 1.5648e-13 141502400.0 174693.0 158685.9 187537.0 153396.0 160811.0 139906.0 109154.0 113975.1 134325.0 109334.3 True False 172201.84578522725 158318.47254818265 172118.43177375454 164677.2535540555 151352.41314659023 133922.54651681526 114805.460025376 119270.79923255868 119195.90399504229 128232.58807620278 1.3428867682440875 1.2346196464045567 1.3422362782810904 1.2842075171733671 1.1802960184867235 1.044372171894645 0.895290828546269 0.9301130159026463 0.9295289581475935 1.0 16.96840341877604 -6.728963533840165 1.7633659296584465 0.9319648559387925 1.3007883038567087 0.9447290151610819 0.03973972874054156 0.07047466380676051 0.45299172056883336 0.01586585233124584 0.014846351499340774 1.866536410665107e-07 6.728963533840165 0.3688234479179162 AGS(ph)PGEEQAHSCSTLSLLSEK ddPTM_PC-9_AZD4547_30min_R2 2 AGSPGEEQAHSCSTLSLLSEK 21 0 A0A0C4DGC7;Q9NZ71-5;Q9NZ71-9;Q9NZ71-8;Q9NZ71-4;Q9NZ71;Q9NZ71-7;Q9NZ71-6;Q9NZ71-2 A0A0C4DGC7 RTEL1 Regulator of telomere elongation helicase 1 1 AGS(0.879)PGEEQAHS(0.12)CS(0.001)TLSLLSEK;AGS(1)PGEEQAHSCSTLSLLSEK 113.3 4.3995e-06 9277300.0 30515.0 27797.0 50123.0 83695.0 59406.0 62120.0 46140.0 62352.0 45091.0 58400.0 True False 40218.13524857019 36781.83665003824 49458.336270213564 64400.41082485994 51158.50232220185 58235.62657988543 50246.37061497619 52716.93110642031 47474.418204899004 56355.43377557652 0.7136514184014681 0.6526759566169616 0.877614330273294 1.1427542387717362 0.9077829571134108 1.0333631147583102 0.8915976197623042 0.9354365244770224 0.8424106607706319 1.0 15.782267100916506 -5.391335854248975 4.340227115814235 0.962525909328213 0.6854483380611331 0.6525135432518914 0.08078544079367683 0.13000615593574022 3.928330982129135 0.021449799086973913 0.04716105588859951 4.061291346355344e-06 5.391335854248975 -0.2770775712670799 AGS(ph)PGEEQAHSCSTLSLLSEK ddPTM_PC-9_Lapatinib_30min_R1 1 AGSPGEEQAHSCSTLSLLSEK 21 0 A0A0C4DGC7;Q9NZ71-5;Q9NZ71-9;Q9NZ71-8;Q9NZ71-4;Q9NZ71;Q9NZ71-7;Q9NZ71-6;Q9NZ71-2 A0A0C4DGC7 RTEL1 Regulator of telomere elongation helicase 1 1 AGS(0.996)PGEEQAHS(0.004)CSTLSLLSEK 75.044 0.00084451 4784700.0 36463.0 27571.0 42548.0 34050.0 35680.0 45756.0 32848.0 31222.0 39040.0 32372.0 True False 35943.030933504735 27507.16104345719 39049.8676800296 36554.1505874702 33581.37254957896 43799.12254244557 34548.708713501626 32672.688101514752 34642.9040905747 37967.457067021365 0.9466799651621901 0.724493109846695 1.0285089046416127 0.9627758457181803 0.884477790817016 1.1535964198268522 0.909955824866415 0.8605445459209944 0.9124367752473374 1.0 15.212475754865348 -5.274069935389555 24.940796100818577 0.9610085252919296 0.8355865244137662 0.22873193000479042 0.09421726402579667 975.7250341948834 1926706.1716987009 0.024667428466844894 0.05188389512932249 5.320225796096784e-06 5.274069935389555 -0.12542200087816335 AGS(ph)PGTDQER ddPTM_PC-9_AZD4547_30min_R2 1 AGSPGTDQER 10 0 S4R3K6;Q86VQ0 S4R3K6 LCA5 Lebercilin 1 AGS(0.637)PGT(0.363)DQER 77.062 0.022281 3624900.0 16178.0 14623.0 17794.0 26368.0 22338.0 23147.0 18784.0 17705.0 21990.0 18950.0 True False 21322.267476695662 19349.59878164942 17558.039933606935 20289.264981539007 19236.75428194701 21699.61443085332 20455.739610570286 14969.099070425515 23152.346506525246 18286.566267931084 1.1660071751189423 1.0581318820681258 0.9601605723212369 1.1095174831767094 1.0519609860098371 1.1866423752231523 1.1186211402871873 0.8185844652900545 1.266084959160825 1.0 14.158496580207581 -11.23110016662944 2.554189543323339 0.9867512353352808 1.0738456461405421 0.03741942680061505 0.11843080652706918 33641596.897255294 27541345.25513972 2871026.798940893 0.027855379768080276 5.873538683250077e-12 11.23110016662944 0.08709441080526137 AGS(ph)PINLSQHSLVIK ddPTM_PC-9_AZD4547_30min_R2 1 AGSPINLSQHSLVIK 15 0 P48552 P48552 NRIP1 Nuclear receptor-interacting protein 1 1 AGS(1)PINLSQHSLVIK 139.46 3.4813e-05 11111000.0 19287.0 21868.0 60643.0 114720.0 94226.0 73939.0 37214.0 91628.0 49387.0 70229.0 True False 25419.86480547838 28936.403347952517 59838.83419656767 88273.07640633173 81144.34635915203 69315.58264150283 40525.97390692947 77468.9980019739 51997.495994441175 67770.3040860439 0.37508854576193573 0.426977622989764 0.8829654079845042 1.3025332790931066 1.197343695789352 1.022801706090871 0.5979901441120297 1.1431112645387593 0.76726077440088 1.0 16.048365624403452 -5.300775517497295 3.807403086263423 1.0072039721453134 0.38620493048980703 0.6039540369706927 0.19242951369401914 0.14748886988176793 4.57758990231641 0.05393407080941506 0.13333075577130496 5.0029306466990745e-06 5.300775517497295 -0.6209990416555065 AGS(ph)PINLSQHSLVIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGSPINLSQHSLVIK 15 0 P48552 P48552 NRIP1 Nuclear receptor-interacting protein 1 1 AGS(0.998)PINLS(0.002)QHSLVIK 92.236 0.0020712 3485200.0 23077.0 20482.0 38969.0 47098.0 55591.0 58835.0 49154.0 42693.0 50606.0 32438.0 True False 26983.480308473892 22515.317599177684 39898.16875075548 44459.25175377622 44698.342613332556 55749.589026901886 44497.777275857596 41572.35398697265 51346.017012853976 38318.75262093331 0.7041847258288094 0.5875796068287906 1.0412178377894103 1.160247886813737 1.1664874129778984 1.4548904965253544 1.1612532828521334 1.0849088538508929 1.339970993335622 1.0 15.225762977761224 -5.4180912501483265 2.731645552818187 1.2067356275730838 0.6379357648619076 0.7507013226706358 0.12425480267140228 0.12646182450122023 1.804300973053286 0.034154668478388356 0.08533787972117517 3.818640284892286e-06 5.4180912501483265 -0.5687998627111762 AGS(ph)PINLSQHSLVIK ddPTM_PC-9_Lapatinib_30min_R1 2 AGSPINLSQHSLVIK 15 0 P48552 P48552 NRIP1 Nuclear receptor-interacting protein 1 1 AGS(1)PINLSQHSLVIK;AGS(1)PINLSQHSLVIK 127.59 0.00012228 6237300.0 67320.0 41368.0 87875.0 48750.0 73315.0 86069.0 57387.0 57817.0 97743.0 51145.0 True False 66360.00445502413 41272.214937642355 80650.2567073096 52335.237625232665 69002.75584283576 82388.02950663854 60358.21806325249 60503.388891335555 86734.15406057994 59985.345103571264 1.1062702788563827 0.6880383011280732 1.344499336763973 0.8724670589936617 1.150326896072615 1.3734692926144976 1.0062160675917997 1.0086361724996302 1.4459223983928728 1.0 15.872322461456635 -5.262573448980335 24.999642247997897 1.143418823140073 0.8971543039888373 0.20196481878972106 0.2008348960748887 149.2719324203472 3290668.790128961 0.049832622727813934 0.11401921057275494 5.462941514212523e-06 5.262573448980335 -0.2462645191512357 AGS(ph)PLCNSNLQDSEEDIEPSYSLFR ddPTM_PC-9_AZD4547_30min_R2 2 AGSPLCNSNLQDSEEDIEPSYSLFR 25 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 AGS(0.999)PLCNS(0.001)NLQDSEEDIEPSYSLFR;AGS(0.996)PLCNS(0.004)NLQDSEEDIEPSYSLFR 145.4 3.4653e-09 16239700.0 23198.9 24318.0 29027.0 42063.0 33963.0 41024.0 28717.0 32784.0 28867.0 37993.0 True False 30575.667632903616 32178.317935591258 28642.08301409512 32366.025216871763 29247.82369405348 38458.762794803944 31272.757367799542 27717.986101374187 30392.85068685147 36662.876634169195 0.8339680472428506 0.8776812102518327 0.7812284698741061 0.8828010289489168 0.7977503780157553 1.0489837766565488 0.852981550789003 0.7560232214714293 0.8289816151121605 1.0 15.162032366273777 AGS(ph)PLCNSNLQDSEEDIEPSYSLFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGSPLCNSNLQDSEEDIEPSYSLFR 25 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 AGS(0.994)PLCNS(0.006)NLQDSEEDIEPSYSLFR 151.35 3.0644000000000004e-07 4362400.0 8494.0 7573.5 7642.6 6652.6 8317.2 7215.1 9535.3 9312.1 7269.7 4829.4 True False 9931.866435852899 8325.34702848219 7824.828568721903 6279.876390020206 6687.5043655197705 6836.72745454237 8632.047354406259 9067.66724198552 7376.005609578798 5704.931990490638 1.7409263515161966 1.4593245006880775 1.3715901577380503 1.1007802372557505 1.172232092629141 1.1983889494104898 1.5130850584712898 1.589443530106952 1.2929173602548842 1.0 12.47799397265427 -4.824331623016052 1.8723902201972273 1.2951049229713263 1.8535240484806617 0.414356794386581 0.16961668774371086 0.8442204754148294 3.3656256840286534 0.05011261666613192 0.8127944803077577 1.4985401279383836e-05 4.824331623016052 0.5584191255093354 AGS(ph)PLCNSNLQDSEEDIEPSYSLFR ddPTM_PC-9_Lapatinib_30min_R1 1 AGSPLCNSNLQDSEEDIEPSYSLFR 25 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 AGS(1)PLCNSNLQDSEEDIEPSYSLFR 142.9 1.0366e-06 5795500.0 7404.8 8475.3 7784.8 7070.2 7701.2 7055.6 5511.1 6470.7 9566.6 6755.0 True False 7299.206194125989 8455.675963570884 7144.763794197013 7590.166093495797 7248.230557141753 6753.848435406921 5796.437791980602 6771.3523444517205 8489.10876723596 7922.59274952828 0.9213153351294741 1.0672864592307036 0.9018214137817977 0.9580406734837814 0.9148811236792804 0.8524795668449641 0.731633945506757 0.8546889330964151 1.0715063913567198 1.0 12.95175692895104 -5.937286776131759 1.435493106588422 0.8855282929182724 0.9839583438759286 0.0662575038552603 0.09498168901696899 0.8689345625363813 3.635645669102679 0.034043118281564415 0.06477715441480777 1.1553490826989457e-06 5.937286776131759 0.09843005095765622 AGS(ph)PSPQPSGELPR ddPTM_PC-9_AZD4547_30min_R2 2 AGSPSPQPSGELPR 14 0 Q92619 Q92619 HMHA1 Minor histocompatibility protein HA-1;Minor histocompatibility antigen HA-1 1 AGS(0.674)PS(0.326)PQPSGELPR;AGS(0.994)PS(0.006)PQPSGELPR 143.64 0.00016779 12335800.0 15674.9 17305.8 19960.4 26053.0 26114.0 25061.0 26601.0 29563.0 18945.6 22398.7 True False 20659.19214182573 22899.56141663603 19695.712054106323 20046.883364837508 22488.521860451445 23493.93170828251 28968.437467034706 24994.71764015755 19947.025737791013 21614.528330633682 0.955801201201602 1.0594522844239493 0.9112256234706786 0.9274726266603563 1.0404354662034923 1.0869509317483095 1.3402299149863255 1.1563850599845482 0.9228526957731775 1.0 14.399713733827204 -6.6259858827708165 2.943601884345532 1.1269768801374318 0.9679000773199798 0.24615414835606764 0.10911039401360435 0.34171713878969534 5.965518578774194 0.04008469028994289 0.04017112336519642 2.3659966056088243e-07 6.6259858827708165 -0.15907680281745196 AGS(ph)PSPQPSGELPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGSPSPQPSGELPR 14 0 Q92619 Q92619 HMHA1 Minor histocompatibility protein HA-1;Minor histocompatibility antigen HA-1 1 AGS(0.977)PS(0.023)PQPSGELPR 109.07 0.00062469 6883600.0 8547.2 9715.7 12363.0 14840.0 13960.0 9276.8 15455.0 12599.0 13607.0 9345.1 True False 9994.072145105 10680.210487175595 12657.7808069386 14008.562911929148 11224.6382126985 8790.30827712694 13990.990515489679 12268.289599743948 13805.976633085087 11039.292654229102 0.9053181628694585 0.9674723573057966 1.1466115813216946 1.2689728726923941 1.01678962269366 0.7962745940755012 1.2673810681275666 1.1113293200940753 1.2506214904807402 1.0 13.430360113537898 AGS(ph)PSPQPSGELPR ddPTM_PC-9_Lapatinib_30min_R1 1 AGSPSPQPSGELPR 14 0 Q92619 Q92619 HMHA1 Minor histocompatibility protein HA-1;Minor histocompatibility antigen HA-1 1 AGS(0.994)PS(0.006)PQPSGELPR 139.21 9.9119e-05 6082300.0 13452.0 12811.0 11488.0 11147.0 14963.0 11249.0 11223.0 10713.0 16954.0 9002.9 True False 13260.172013205334 12781.336916605502 10543.500984962402 11966.787565301924 14082.905758389863 10767.906492699763 11804.072025439258 11210.765089729292 15044.461986465256 10559.03926938981 1.2558123589563672 1.2104640006082783 0.9985284376702289 1.1333216270909336 1.3337298402910185 1.019780892748022 1.1179115565616602 1.0617220756275436 1.424794586196728 1.0 13.366190954365077 AGS(ph)PSRDVGPSLGLK ddPTM_PC-9_AZD4547_30min_R2 2 AGSPSRDVGPSLGLK 15 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 AGS(0.919)PS(0.081)RDVGPSLGLK;AGS(0.428)PS(0.428)RDVGPS(0.143)LGLK 159.54 0.001291 59746000.0 64917.0 56038.0 82434.0 103765.0 107459.0 102397.0 76831.0 107304.0 71655.0 92329.0 True False 85559.25564251772 74151.18761718324 81340.87129858119 79843.5824032689 92540.17272735902 95994.09940277717 83668.81015863088 90722.63240061785 75442.53701341817 89096.58981276027 0.9602977602433899 0.8322561814432479 0.9129515671646018 0.8961463347930947 1.038649996838662 1.0774160897124376 0.9390798271231697 1.0182503347353111 0.8467499953922301 1.0 16.443082592953523 -6.240203040649574 23.615433621265304 0.9897592456998652 0.8964402056816102 0.29465016105881303 0.06517728277253365 490.6602401093794 545627.423851385 0.019193787960392134 0.02474795409861494 5.751709714720461e-07 6.240203040649574 -0.09331904001825497 AGS(ph)PSRDVGPSLGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AGSPSRDVGPSLGLK 15 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 AGS(0.89)PS(0.11)RDVGPS(0.001)LGLK;AGS(0.943)PS(0.057)RDVGPSLGLK;AGS(0.795)PS(0.205)RDVGPSLGLK;AGS(0.982)PS(0.018)RDVGPSLGLK 120.59 0.00038204 84628100.0 89134.0 57292.6 76333.0 111921.0 116175.0 103517.0 110195.0 118559.0 107623.0 88367.0 True False 104222.62572325298 62980.23069439742 78153.06821451448 105650.42922277784 93411.34271921532 98088.38628873651 99756.53185728774 115446.95187364395 109196.7827722873 104387.23758721299 0.99842306523513 0.6033326693004877 0.7486841305597296 1.0121010160318638 0.8948540537934287 0.9396587988717112 0.9556391582251 1.1059489123580921 1.0460740728104434 1.0 16.671585812827978 -6.388516843070016 0.7668803238378274 1.0417368797854112 0.7722579633421471 0.38939998679318855 0.11114816129807029 0.6793859502646907 0.8797968056925595 0.06766375548922957 0.10089363472765035 4.0877389848831156e-07 6.388516843070016 -0.26947891644326405 AGS(ph)PSRDVGPSLGLK ddPTM_PC-9_Lapatinib_30min_R1 2 AGSPSRDVGPSLGLK 15 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 AGS(0.503)PS(0.372)RDVGPS(0.124)LGLK;AGS(0.943)PS(0.056)RDVGPS(0.001)LGLK 103.39 0.0062479 17599700.0 35873.0 41092.0 49797.0 41418.0 46915.0 39630.0 30895.0 30568.0 46789.0 34485.0 True False 35361.44444169748 40996.853998684936 45702.882881978825 44464.01788639767 44155.55193843882 37935.117282042105 32494.591929604012 31988.300873970376 41519.13010998721 40445.68630162584 0.8742945830610375 1.0136273542980265 1.129981638613996 1.099351301763182 1.091724630635427 0.9379273972294342 0.8034130435387813 0.7908952424596267 1.0265403781346694 1.0 15.30369822106469 -6.922560100695214 5.164612525688345 0.8854605669818971 1.047454718820798 0.3106656750794762 0.09564302109800392 0.22434566543779544 10.648615637198766 0.03552518318209449 0.03111562222159757 1.1951981143891217e-07 6.922560100695214 0.16199415183890098 AGS(ph)SGSSSGGGGGGPGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGSSGSSSGGGGGGPGGR 18 0 P48634;P48634-2;P48634-3 P48634 PRRC2A Protein PRRC2A 1 AGS(0.877)S(0.118)GS(0.003)S(0.001)S(0.001)GGGGGGPGGR 99.055 0.0056007 0.0 0.0 687.07 0.0 0.0 974.62 955.31 374.42 0.0 770.91 570.49 True False 0.0 755.2777689125577 0.0 0.0 783.6502073682101 905.2118618728597 338.95222703394643 0.0 782.1831003315667 673.9153210036451 0.0 1.1207309662996554 0.0 0.0 1.162831861725802 1.343213062027957 0.5029596693678865 0.0 1.1606548715448124 1.0 9.396423514649213 -6.259701300477584 24.99581547276425 0.8177575522628586 0.32020885636156027 0.25964953786193656 0.4756293463916421 278.80742639863854 4009609.234420052 0.15112282263518298 0.18510592749923832 5.499189676745161e-07 6.259701300477584 -0.49754869590129835 AGS(ph)SGSSSGGGGGGPGGR ddPTM_PC-9_Lapatinib_30min_R1 1 AGSSGSSSGGGGGGPGGR 18 0 P48634;P48634-2;P48634-3 P48634 PRRC2A Protein PRRC2A 1 AGS(0.421)S(0.133)GS(0.06)S(0.124)S(0.262)GGGGGGPGGR 120.59 0.00050013 0.0 0.0 392.4 521.97 0.0 597.21 0.0 901.69 525.7 811.17 739.66 True False 0.0 391.4914219089839 479.0556414624672 0.0 562.0832819600353 0.0 948.3750961969454 550.1259411622036 719.807492601216 867.5092454650021 0.0 0.4512821320989343 0.5522196379655687 0.0 0.6479277136219425 0.0 1.0932161255395008 0.6341441823681374 0.8297404279713296 1.0 9.760735323045372 -7.26555356945638 24.999852340156522 0.8587872021344685 0.3002599051722218 0.5977795929262084 0.24573129765091722 266.02101245459284 1616465.4644827724 0.09523073652446748 0.06682152846723755 5.425583235915804e-08 7.26555356945638 -0.5585272969622467 AGS(ph)SPAQGAQNEPPR ddPTM_PC-9_AZD4547_30min_R2 1 AGSSPAQGAQNEPPR 15 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 AGS(0.597)S(0.403)PAQGAQNEPPR 133.87 6.7725e-06 5663800.0 11559.0 6273.6 10402.0 13752.0 12801.0 12562.0 11234.0 13120.0 10712.0 14331.0 True False 15234.521557864087 8301.418513065435 10264.062683453943 10581.68886628203 11023.80211134406 11776.496154161638 12233.804236858321 11092.605467607045 11278.214451018577 13829.276052016912 1.101613815543311 0.6002786032935343 0.7421981197603612 0.7651657849970214 0.7971351551505337 0.8515627361740393 0.8846308505841199 0.802110350960075 0.8155318043111679 1.0 13.755438014454187 -6.738963969827084 3.7474734230332625 0.860260762125248 0.7834224967934622 0.05893334106032111 0.1274150278187982 0.6536873872025857 19.647259537560224 0.04365819138414819 0.041383849349820534 1.824047023614987e-07 6.738963969827084 -0.07683826533178584 AGS(ph)SPAQGAQNEPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGSSPAQGAQNEPPR 15 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 AGS(0.591)S(0.409)PAQGAQNEPPR;AGS(0.881)S(0.119)PAQGAQNEPPR 153.94 1.0298999999999999e-06 7498800.0 30103.0 31153.3 34126.0 34935.0 41388.0 38814.0 32309.0 30679.0 29893.0 29766.0 True False 35198.84333864841 34245.99373901289 34939.6932635757 32977.70521079814 33278.31850624395 36778.52551185808 29248.45762309645 29873.70875708744 30330.128573000107 35162.340172473654 1.0010381324449882 0.973939549274422 0.9936680292663725 0.9378700350727589 0.9464193322461347 1.045963531763157 0.8318120318394847 0.8495938726078777 0.8625742320968621 1.0 15.101743469452632 -7.2697312450375735 24.99978261055198 0.8734611892598043 0.9794814904989695 0.4541450658123841 0.051357614251627014 521.4555471752724 1572169.9039467878 0.02036479374806551 0.01397908636988857 5.373642312351284e-08 7.2697312450375735 0.10602030123916517 AGS(ph)SPAQGAQNEPPR ddPTM_PC-9_Lapatinib_30min_R1 2 AGSSPAQGAQNEPPR 15 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 AGS(0.879)S(0.121)PAQGAQNEPPR;AGS(0.71)S(0.29)PAQGAQNEPPR 115.58 0.0022259 0.0 25618.7 37188.0 39089.0 32485.3 39598.0 40976.0 42412.0 43202.0 43603.0 39427.0 True False 25253.372640105805 37101.89347082391 35875.253307903506 34874.37732978404 37268.923492663365 39223.55199972135 44607.88583649021 45209.32263665496 38691.97098005451 46241.90441682481 0.5461144595705175 0.8023435439939328 0.7758169513202517 0.754172601011978 0.8059556361848998 0.8482252730372005 0.9646636832772815 0.9776699988205038 0.8367296171733077 1.0 15.49691319425941 -3.464238251526749 0.24398314696246554 0.9926475137202643 6.0220531598214385e-15 0.7372608317616167 0.06480127858722476 10.831665639298766 0.3278175061514602 0.09398125406827626 3.607174488851904 0.0003433695256172456 3.464238251526749 -0.9926475137202583 AGS(ph)WPHCPGAQPPALEGPWSPR ddPTM_PC-9_AZD4547_30min_R2 1 AGSWPHCPGAQPPALEGPWSPR 22 0 Q8IW93-2;Q8IW93 Q8IW93-2 ARHGEF19 Rho guanine nucleotide exchange factor 19 1 AGS(1)WPHCPGAQPPALEGPWSPR 87.098 0.00012465 4900900.0 10585.0 4281.1 16128.0 20234.0 19959.0 18257.0 13498.0 18390.0 12283.0 15997.0 True False 13950.809818322638 5664.881853526591 15914.132182151996 15569.363912183708 17188.037367417863 17115.386903879084 14699.295850909157 15548.248060159567 12932.254303758507 15436.949899107838 0.9037283860802651 0.3669689861372153 1.0309116947429968 1.0085777316076878 1.1134348093214468 1.1087285387165926 0.9522150390446423 1.0072098543934616 0.8377467302984454 1.0 13.91410010624064 -5.289445518386852 24.770994227477367 1.0130942960866065 0.6353486708172789 0.52728678436517 0.14080713357767252 391.5391854074899 346309.70722791937 0.03475314691442697 0.07236973933401941 5.135165933746249e-06 5.289445518386852 -0.37774562526932765 AGSALPGFANSPAGS(ph)TSVVLVPPAHGTLVPDGNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNK 34 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0 O15027 SEC16A Protein transport protein Sec16A 1 AGSALPGFANS(0.158)PAGS(0.407)T(0.32)S(0.114)VVLVPPAHGTLVPDGNK 77.09899999999999 2.2375e-06 0.0 3973.7 7180.7 11823.0 12752.0 14167.0 13755.0 10592.0 9668.8 11997.0 7807.8 True False 4646.368925847497 7893.552440406949 12104.905158977186 12037.54678254181 11391.078048660436 13033.663585706403 9588.649080560761 9415.004244940414 12172.433428905839 9223.29233348921 0.503764681617736 0.8558280660525032 1.312427788396668 1.30512471548085 1.2350338292217118 1.413124848963311 1.039612400199543 1.0207856267067574 1.319749281361112 1.0 13.171066109649678 -4.979726453704535 2.8964953414446812 1.2115482933256225 0.49871588484953905 0.7261875747551259 0.1371337035465441 0.15132610747521014 2.334741484536897 0.03694071734785349 0.20525725466215178 1.0477883039873851e-05 4.979726453704535 -0.7128324084760835 AGSALPGFANSPAGST(ph)SVVLVPPAHGTLVPDGNK ddPTM_PC-9_AZD4547_30min_R2 2 AGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNK 34 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0 O15027 SEC16A Protein transport protein Sec16A 1 AGS(0.003)ALPGFANS(0.172)PAGS(0.198)T(0.307)S(0.307)VVLVPPAHGT(0.011)LVPDGNK;AGS(0.001)ALPGFANS(0.079)PAGS(0.24)T(0.338)S(0.338)VVLVPPAHGT(0.004)LVPDGNK 52.107 0.007813800000000001 14313300.0 13542.5 14271.2 43136.0 77351.0 71615.0 58816.0 38471.0 73206.0 43108.0 55770.0 True False 17848.733298501116 18884.086311473384 42563.9884554383 59518.922011037015 61672.49341488198 55138.226222191624 41894.844471797776 61893.69480652763 45386.60087327378 53817.50927506684 0.33165290514048873 0.3508911238339714 0.790894804103426 1.1059397362079628 1.145955921142086 1.024540655353901 0.7784612301113547 1.1500661334990918 0.8433426497182949 1.0 15.715788002789765 -5.377193224840176 2.907364848481378 1.0089084251199247 0.3250399494999469 0.83858638929255 0.11522275232412524 0.09576752366227145 1.533059978179339 0.03191675809184715 0.08102417353649276 4.195722677753292e-06 5.377193224840176 -0.6838684756199778 down AGSALPGFANSPAGST(ph)SVVLVPPAHGTLVPDGNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNK 34 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0 O15027 SEC16A Protein transport protein Sec16A 1 AGSALPGFANS(0.217)PAGS(0.139)T(0.321)S(0.321)VVLVPPAHGT(0.001)LVPDGNK 53.97 0.0027946 4525300.0 5065.5 6698.5 17779.0 16990.0 21166.0 20786.0 16295.0 13862.0 15289.0 10774.0 True False 5922.989101814557 7363.48281115573 18202.918787232975 16038.105382323198 17018.67424140232 19695.9455683383 14751.419634416314 13498.137188003058 15512.572701053725 12727.24091306293 0.46537887844452963 0.5785608099551279 1.4302329084185044 1.260140001424981 1.3371848900836605 1.5475424487425913 1.1590430113785162 1.060570573009968 1.2188480446796601 1.0 13.635632076677894 -5.219237980318226 7.160664985418496 1.2643440746182517 0.5141249524637005 0.7774196791877048 0.15609764528108777 0.11072902192177475 15.650440495199058 0.041324136266784516 0.10933079196807331 6.0361777434388395e-06 5.219237980318226 -0.7502191221545512 AGSATVLS(ph)GSIAGLEGGSQLALR ddPTM_PC-9_Lapatinib_30min_R1 1 AGSATVLSGSIAGLEGGSQLALR 23 0 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614;Q92614-5;Q92614-2 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 AGS(0.016)AT(0.113)VLS(0.802)GS(0.069)IAGLEGGSQLALR 214.42 1.7380999999999997e-37 4157500.0 10084.0 11046.0 10672.0 10800.0 9570.7 9186.5 6311.6 5816.3 8510.7 5217.1 True False 9940.200310820881 11020.423665664212 9794.589355111311 11594.268027743856 9007.770242720171 8793.614809777437 6638.38376510402 6086.546531447072 7552.135344355893 6118.868783651219 1.624516011420238 1.8010557270175946 1.600718972971134 1.894838480393983 1.4721299902340939 1.4371308032087196 1.084903762414529 0.9947176098479987 1.2342371786978283 1.0 12.579049246229685 -6.929362978217008 1.5374601179725478 1.0669268295920573 1.7211896824557331 0.8608131564480737 0.11510658921128826 0.12798342429766812 0.619915279599771 0.052510723485715304 0.04147567791164457 1.1766221554957522e-07 6.929362978217008 0.6542628528636758 AGSATVLSGS(ph)IAGLEGGSQLALR ddPTM_PC-9_AZD4547_30min_R2 3 AGSATVLSGSIAGLEGGSQLALR 23 0 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614;Q92614-5;Q92614-2 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 AGSATVLS(0.004)GS(0.993)IAGLEGGS(0.003)QLALR;AGSATVLS(0.006)GS(0.994)IAGLEGGSQLALR;AGS(0.017)AT(0.326)VLS(0.236)GS(0.421)IAGLEGGSQLALR 266.53 8.238999999999997e-96 15258700.0 40794.0 40617.0 45550.0 72836.0 57461.0 71008.0 54552.0 76003.0 52184.0 66377.0 True False 53765.64343208816 53745.65094127433 44945.97723815869 56044.7855049824 49483.53199905798 66567.8585348441 59407.022318772935 64258.48272519354 54942.3397042525 64053.16143358635 0.8393909407240605 0.8390788173195888 0.7016980307015918 0.8749729794850571 0.7725384804052972 1.039259531379495 0.9274643278984633 1.0032054825556125 0.8577615604691047 1.0 15.9669821581101 -6.751742728420857 24.999865978625913 0.9633589110850312 0.8054881801794305 0.6147452559607189 0.06332015657078947 134.11486541270236 345773.83274625824 0.02008563230466864 0.01984455796366011 1.7711578632870683e-07 6.751742728420857 -0.15787073090560078 AGSATVLSGS(ph)IAGLEGGSQLALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGSATVLSGSIAGLEGGSQLALR 23 0 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614;Q92614-5;Q92614-2 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 AGSAT(0.011)VLS(0.006)GS(0.983)IAGLEGGSQLALR;AGSATVLS(0.073)GS(0.927)IAGLEGGSQLALR 193.06 4.4739e-23 13865400.0 45100.0 44698.0 57244.0 49741.0 51589.0 42310.0 42113.0 38009.0 35269.0 33064.0 True False 52734.5392343967 49135.32204120909 58608.91405907892 46954.173032497805 41480.50578473518 40091.18911750181 38123.75176828315 37011.304023864395 35784.74240260735 39058.24146552002 1.3501513958571303 1.2580013896576718 1.5005517877915193 1.202157887060742 1.0620167275414458 1.0264463430309236 0.9760744554241692 0.947592688127994 0.9161892870726793 1.0 15.253339375213338 -6.2282971134363265 1.948368618776125 0.9714561565274032 1.3594491117311813 0.8711494047272718 0.06637534678378987 0.11240184473999672 0.8387312447409376 0.022863119944731614 0.030622808706161228 5.911570681277966e-07 6.2282971134363265 0.3879929552037781 AGSATVLSGS(ph)IAGLEGGSQLALR ddPTM_PC-9_Lapatinib_30min_R1 2 AGSATVLSGSIAGLEGGSQLALR 23 0 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614;Q92614-5;Q92614-2 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 AGS(0.001)AT(0.001)VLS(0.12)GS(0.877)IAGLEGGS(0.001)QLALR;AGSATVLS(0.024)GS(0.976)IAGLEGGS(0.001)QLALR 157.02 4.2861e-07 3420200.0 21409.9 14449.1 20285.3 18478.3 20471.3 14942.8 13759.5 12765.0 16477.9 12071.9 True False 21104.590899905197 14415.643996700066 18617.520937522444 19837.255823801795 19267.218382124323 14303.731277368124 14471.899584249442 13358.10850092358 14621.985382020524 14158.511830204361 1.4905938669968664 1.0181609599638264 1.3149348717430653 1.4010833950417703 1.3608222822557916 1.0102566886199131 1.0221342297695815 0.9434683998657768 1.032734623339964 1.0 13.78938201446103 -6.769253125908589 24.606389841495997 0.9994614360711468 1.3050536347085797 0.6490995403532451 0.11577361713818399 96.55289110029736 304053.9074266905 0.04065756246359506 0.03652354803684202 1.7011667046784706e-07 6.769253125908589 0.3055921986374329 AGSCCLS(ph)PGGR ddPTM_PC-9_AZD4547_30min_R2 1 AGSCCLSPGGR 11 0 W0Z7M9;A0A499FIJ6;Q969V6;E7ER32;A0A087X287;A0A087WU73;A0A494BZX7;B0QY83 W0Z7M9 mkl1;MKL1 MKL/myocardin-like protein 1 1 AGSCCLS(1)PGGR 115.92 0.0013119000000000002 29481000.0 53163.0 54100.0 78560.0 112960.0 69863.0 72653.0 50006.0 78019.0 48748.0 58211.0 True False 70067.72814090566 71586.7670168387 77518.2430698079 86918.81721460276 60163.72837316068 68109.99642479753 54456.43712554183 65962.95624826492 51324.719758985535 56173.050608049445 1.2473548682589288 1.2743969971711044 1.379989910298725 1.547340161763398 1.0710425679558764 1.2125030719808825 0.9694406220789862 1.1742811817098038 0.9136893795764556 1.0 15.777590533500272 -6.2905265205203715 24.023797345503706 1.0689546902656557 1.3572594602785584 0.6387807003721984 0.11227726600598556 294.38835546242416 243141.76993106678 0.03495738330449426 0.03964569121873354 5.122399889878411e-07 6.2905265205203715 0.28830477001290267 AGSCCLS(ph)PGGR ddPTM_PC-9_Lapatinib_30min_R1 2 AGSCCLSPGGR 11 0 W0Z7M9;A0A499FIJ6;Q969V6;E7ER32;A0A087X287;A0A087WU73;A0A494BZX7;B0QY83 W0Z7M9 mkl1;MKL1 MKL/myocardin-like protein 1 1 AGSCCLS(1)PGGR;AGS(0.001)CCLS(0.999)PGGR 103.43 0.0029083000000000004 37424000.0 49158.0 57000.0 73768.0 46551.0 83331.0 110273.0 104501.0 106143.0 137927.0 84986.0 True False 48456.99790552685 56868.02000206954 67703.07979271477 49974.51582958375 78429.63441504946 105556.88084891827 109911.55045267995 111074.79127407227 122392.20882430064 99675.71686327312 0.4861464700775229 0.5705303336827401 0.6792334374237231 0.5013710199660228 0.7868479593944905 1.0590029765596012 1.1026913466140154 1.1143615994900289 1.227903973765126 1.0 16.60495445560722 -6.628936546528129 2.2758783552442745 1.1195578762078613 0.5670305911724831 0.9255799434427346 0.07257920972603783 0.07331726290177398 0.7741502812193786 0.02653697740438788 0.026644012414326883 2.3499761437744982e-07 6.628936546528129 -0.5525272850353782 AGSES(ph)PHPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGSESPHPGR 10 0 Q9HCH0;H7C1V4;Q9HCH0-2 Q9HCH0 NCKAP5L Nck-associated protein 5-like 1 AGS(0.004)ES(0.996)PHPGR;AGS(0.054)ES(0.946)PHPGR 107.09 0.0012595 4922100.0 11069.3 17565.8 145429.0 29917.1 85177.0 57627.5 32654.6 32767.1 54671.7 36539.2 True False 12943.113861359368 19309.616535672067 148896.57890255403 28240.941879546845 68487.17829821073 54605.412452584154 29561.31988916914 31906.998344612253 55471.17018380528 43163.46771585196 0.2998626974682564 0.44736017649899174 3.4495972353924462 0.6542788004304677 1.5866931440510403 1.2650840014072848 0.6848689749343893 0.739213043647424 1.2851416514765626 1.0 15.397523153909551 -7.126608160352294 6.440662808019061 0.9076598205234876 1.3349571087875292 0.03956188006165762 0.8418676096694809 0.8704471857115185 41.938053394344585 0.3301201508720691 0.2553585864093079 7.47122541334558e-08 7.126608160352294 0.42729728826404156 AGSES(ph)PHPGR ddPTM_PC-9_Lapatinib_30min_R1 2 AGSESPHPGR 10 0 Q9HCH0;H7C1V4;Q9HCH0-2 Q9HCH0 NCKAP5L Nck-associated protein 5-like 1 AGS(0.063)ES(0.937)PHPGR;AGS(0.011)ES(0.989)PHPGR 89.189 0.0053887 6298300.0 23329.7 26794.0 119892.0 27502.0 53442.0 63686.0 36410.0 41074.0 107788.0 28615.0 True False 22997.014199857003 26731.96013921844 110034.94255650332 29524.588823982544 50298.646631014584 60962.298239317024 38295.13164450176 42982.44798800901 95647.78038204068 33561.06462290921 0.6852289835930577 0.7965170485375743 3.2786487494616625 0.8797274209182472 1.4987202341811316 1.816459010591201 1.141058308929837 1.2807236144311298 2.8499626414339163 1.0 15.034500861174324 -5.041326539034631 24.99945767614785 1.6975918678017583 0.7130451222680265 0.21700497165540766 0.7430476253475441 623.8352340751524 377373.6119414549 0.18158924971898038 0.4805572535392202 9.092293806158719e-06 5.041326539034631 -0.9845467455337318 AGSIS(ph)SEEVDGSQGNMMR ddPTM_PC-9_AZD4547_30min_R2 1 AGSISSEEVDGSQGNMMR 18 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 AGS(0.028)IS(0.485)S(0.485)EEVDGS(0.001)QGNMMR 57.788000000000004 0.019932 4977000.0 19546.0 17527.0 23628.0 34726.0 26799.0 29014.0 21009.0 29483.0 23560.0 26094.0 True False 25761.221417943696 23192.259990834278 23314.67728173907 26720.457211351757 23078.421434412114 27199.749993380497 22878.760300174155 24927.079801940454 24805.333501306726 25180.45700239547 1.0230640935346398 0.9210420600638006 0.9259036593148844 1.0611585488225963 0.9165211509948614 1.080192865077585 0.9085919408848557 0.9899375455961379 0.9851025936084855 1.0 14.62001684644699 AGSISS(ph)EEVDGSQGNMMR ddPTM_PC-9_AZD4547_30min_R2 1 AGSISSEEVDGSQGNMMR 18 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 AGS(0.002)IS(0.148)S(0.846)EEVDGS(0.003)QGNMMR 97.823 0.00044768 4573100.0 11939.0 14122.0 20116.0 29306.0 25093.0 19683.0 16017.0 20260.0 16837.0 21793.0 True False 15735.353653373077 18686.66032923841 19849.24869643909 22549.95447318652 21609.270086708595 18452.218898452764 17442.481970959558 17129.28252848467 17726.96944658325 21030.033703272955 0.7482324505701646 0.888570156039748 0.9438524434390184 1.0722738152187088 1.0275432931591304 0.877422221895013 0.8294081796095716 0.8145152200026573 0.8429358552965305 1.0 14.360163541721176 -6.980521495949221 24.63844713373442 0.8558516512573321 0.9425539452144259 0.09091335597575845 0.09385133711487989 407.8333397876625 515868.12139292306 0.03528517858840286 0.031114442151574925 1.0458719224415382e-07 6.980521495949221 0.08670229395709383 AGSISS(ph)EEVDGSQGNMMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGSISSEEVDGSQGNMMR 18 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 AGS(0.046)IS(0.127)S(0.828)EEVDGSQGNMMR 111.81 0.0015152999999999998 0.0 12951.0 11856.0 12773.0 14053.0 15670.0 16730.0 16008.0 15129.0 13572.0 13008.0 True False 15143.348506090284 13032.985326425673 13077.55676187226 13265.65597044072 12599.575988036204 15852.649348518215 14491.606352116378 14731.879780500525 13770.464824298575 15366.247428728648 0.9854942513666913 0.8481566750031161 0.8510572813908056 0.8632983447630372 0.8199513932386712 1.0316539169400718 0.943080372701988 0.9587168141623106 0.8961501425880591 1.0 13.907477268913825 -6.753989148498197 24.99999881410672 0.9619125601922203 0.8703547896486502 0.43314399478572274 0.05264659109493741 169.66550754291575 569328.9310207798 0.017418287992248288 0.017088609111400043 1.7620200725872217e-07 6.753989148498197 -0.09155777054357006 AGSNEDPILAPS(ph)GTPPPTIPPDETFGGR ddPTM_PC-9_AZD4547_30min_R2 1 AGSNEDPILAPSGTPPPTIPPDETFGGR 28 0 Q8IZL8;C9JFV4;E7EV54 Q8IZL8 PELP1 Proline-, glutamic acid- and leucine-rich protein 1 1 AGSNEDPILAPS(0.587)GT(0.413)PPPTIPPDETFGGR 99.396 5.661799999999999e-10 10641000.0 8335.1 8183.2 10886.0 16113.0 14732.0 10960.0 10576.0 12988.0 10511.0 12228.0 True False 10985.48841914983 10828.25936880213 10741.644527213957 12398.3967933684 12686.71609283031 10274.669467410566 11517.243511573226 10981.003034548812 11066.590001368204 11799.901441913531 0.9309813707535821 0.9176567636692197 0.9103164615476685 1.0507203686743518 1.075154411694219 0.87074197339604 0.9760457380316502 0.9306012502396018 0.9378544436023349 1.0 13.526487189148735 AGSNEDPILAPS(ph)GTPPPTIPPDETFGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGSNEDPILAPSGTPPPTIPPDETFGGR 28 0 Q8IZL8;C9JFV4;E7EV54 Q8IZL8 PELP1 Proline-, glutamic acid- and leucine-rich protein 1 1 AGSNEDPILAPS(0.575)GT(0.42)PPPT(0.005)IPPDETFGGR;AGSNEDPILAPS(0.61)GT(0.39)PPPTIPPDETFGGR 105.37 1.8405999999999998e-10 13399100.0 90410.5 92300.0 107026.2 114569.4 116786.6 103541.5 113987.1 102731.8 96846.5 84656.4 True False 105715.21196122898 101462.93401055089 109578.11050712367 108150.44795700618 93903.10408962306 98111.60146560661 103189.41669286159 100035.19910333943 98262.69684692245 100003.93518030655 1.0571105204072724 1.0145894141826897 1.0957379858058078 1.0814619220934807 0.9389940897857296 0.9810774074911345 1.0318535616304663 1.0003126269278955 0.9825883018478757 1.0 16.60969724597092 -6.244595415995155 24.992206183167582 0.9908860757035928 1.0612162117636468 0.6008789906289607 0.02915589004294942 641.7687192424008 952223.2796881375 0.009176483506816354 0.01181364333140825 5.693831149513433e-07 6.244595415995155 0.070330136060054 AGSNEDPILAPS(ph)GTPPPTIPPDETFGGR ddPTM_PC-9_Lapatinib_30min_R1 1 AGSNEDPILAPSGTPPPTIPPDETFGGR 28 0 Q8IZL8;C9JFV4;E7EV54 Q8IZL8 PELP1 Proline-, glutamic acid- and leucine-rich protein 1 1 AGSNEDPILAPS(0.499)GT(0.499)PPPT(0.002)IPPDETFGGR 68.562 0.00034158 4433700.0 46120.0 48731.0 50196.0 43838.0 43784.0 47410.0 41265.0 42016.0 43715.0 31622.0 True False 45462.320342627856 48618.166363523735 46069.07864216334 47061.99275928104 41208.711202655984 45382.38481810788 43401.49978880433 43968.21674694908 38791.35636064227 37087.82056633358 1.2258018845112784 1.3108930538683852 1.2421619264406838 1.2689338990709391 1.111111695791128 1.2236465806055932 1.1702359191254819 1.1855163251857719 1.0459324858752974 1.0 15.178657871156199 -8.024084239744713 0.29824558569265486 0.968872926535282 1.297412358522359 0.7354951914887246 0.048281207558002415 0.8015487979662124 0.2599144761737204 0.09701157310268828 0.08559030060464971 9.460536383186084e-09 8.024084239744713 0.3285394319870769 AGSNEDPILAPSGT(ph)PPPTIPPDETFGGR ddPTM_PC-9_AZD4547_30min_R2 5 AGSNEDPILAPSGTPPPTIPPDETFGGR 28 0 Q8IZL8;C9JFV4;E7EV54 Q8IZL8 PELP1 Proline-, glutamic acid- and leucine-rich protein 1 1 AGSNEDPILAPS(0.004)GT(0.995)PPPT(0.001)IPPDETFGGR;AGSNEDPILAPS(0.434)GT(0.566)PPPTIPPDETFGGR;AGSNEDPILAPS(0.026)GT(0.974)PPPTIPPDETFGGR;AGSNEDPILAPS(0.182)GT(0.818)PPPTIPPDETFGGR;AGSNEDPILAPS(0.08)GT(0.92)PPPTIPPDETFGGR 166.65 2.8564000000000003e-13 42152000.0 284184.2 275462.7 379374.0 498854.0 420229.0 381990.0 313190.8 437417.0 339108.6 364043.1 True False 374548.86420143244 364500.6308083066 374343.2528814321 383850.91751747014 361887.45703054534 358104.10491388344 341064.1744690262 369824.2534927041 357033.1882920722 351298.06187509664 1.0661853988098646 1.0375822424488756 1.0656001085896374 1.0926644897174171 1.030143619634354 1.019373984025015 0.9708683636014221 1.0527363900578377 1.0163255282034966 1.0 18.422336091615087 -6.479823881168384 5.082570811383601 1.0135611758955132 1.0636406418201863 0.5543724157549696 0.02264716404709558 0.1697855514122862 10.464310633575742 0.007438298562418875 0.008213730708892416 3.3126543185297597e-07 6.479823881168384 0.05007946592467305 AGSNEDPILAPSGT(ph)PPPTIPPDETFGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 AGSNEDPILAPSGTPPPTIPPDETFGGR 28 0 Q8IZL8;C9JFV4;E7EV54 Q8IZL8 PELP1 Proline-, glutamic acid- and leucine-rich protein 1 1 AGSNEDPILAPS(0.079)GT(0.921)PPPTIPPDETFGGR;AGSNEDPILAPS(0.178)GT(0.822)PPPTIPPDETFGGR;AGSNEDPILAPS(0.15)GT(0.85)PPPTIPPDETFGGR;AGSNEDPILAPS(0.185)GT(0.815)PPPTIPPDETFGGR;AGSNEDPILAPS(0.108)GT(0.866)PPPT(0.027)IPPDETFGGR 131.36 2.8561e-12 33113800.0 186515.8 182306.4 198613.0 222640.0 252034.0 225846.7 228536.0 200866.2 203563.7 169757.2 True False 218089.24108503043 200404.57457097538 203348.68716399744 210166.20260861874 202649.74694120727 214002.90147160713 206887.41562264322 195593.67508533082 206540.43400781488 200532.83656274385 1.0875487766652792 0.9993603940682885 1.0140418429695555 1.0480388459615728 1.0105564276392265 1.0671713677408072 1.0316884714185506 0.9753698119366718 1.0299581731752512 1.0 17.61347896681488 -7.6138387361227835 10.030217039728925 1.0020860909173572 1.0354506773758694 0.2504861334708117 0.027847201906804984 0.5022444946794618 51.22695093054596 0.012640419079447077 0.007286162310949401 2.4331073120067114e-08 7.6138387361227835 0.03336458645851215 AGSNEDPILAPSGT(ph)PPPTIPPDETFGGR ddPTM_PC-9_Lapatinib_30min_R1 5 AGSNEDPILAPSGTPPPTIPPDETFGGR 28 0 Q8IZL8;C9JFV4;E7EV54 Q8IZL8 PELP1 Proline-, glutamic acid- and leucine-rich protein 1 1 AGSNEDPILAPS(0.176)GT(0.824)PPPTIPPDETFGGR;AGSNEDPILAPS(0.169)GT(0.831)PPPTIPPDETFGGR;AGSNEDPILAPS(0.184)GT(0.816)PPPTIPPDETFGGR;AGSNEDPILAPS(0.055)GT(0.945)PPPTIPPDETFGGR;AGSNEDPILAPS(0.033)GT(0.967)PPPTIPPDETFGGR 136.65 6.3679999999999995e-12 47634700.0 311052.4 308745.3 344498.0 302185.1 314442.3 299753.5 267907.2 308686.1 330869.6 225674.6 True False 306616.7357359763 308030.4192271044 316174.70424073655 324408.8003139427 295947.4221313473 286933.74156453717 281778.12393600296 323028.7831200119 293603.5814366497 264682.15391749685 1.158433733433916 1.1637747942882446 1.1945448514798254 1.2256542253130638 1.1181238241834621 1.0840690893499993 1.0645905655726038 1.2204403596500204 1.109268521096318 1.0 18.013901399445118 -6.3902616775113925 6.445160073127905 1.1069084539326741 1.184408079930109 0.37300237920154933 0.05437296422251094 0.3044974019004926 14.664643682632523 0.017152540511482878 0.019442971105314788 4.071348909700758e-07 6.3902616775113925 0.07749962599743498 AGSNMLLIGVHGPTT(ph)PCEEVSMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGSNMLLIGVHGPTTPCEEVSMK 23 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;A0A0A0MT44 O75369-2 FLNB Filamin-B 1 AGSNMLLIGVHGPT(0.122)T(0.849)PCEEVS(0.029)MK 59.818999999999996 0.012749 0.0 15571.0 10079.0 15523.0 12745.0 13362.0 10624.0 16462.0 16038.0 15556.0 8855.4 True False 18206.862758731524 11079.57651020955 15893.127191305322 12030.938969847508 10743.812019919578 10066.85873751689 14902.600185441011 15617.01949366564 15783.477070939342 10460.813920692173 1.7404824229515412 1.0591505206199514 1.5193012046479173 1.150095877917255 1.02705316253333 0.9623399110086439 1.4246119181952654 1.4929067290618903 1.508819217185251 1.0 13.352707486742649 -4.7470931481776395 24.926545120892012 1.250285773757417 1.7404837275921234 0.3242318549299408 0.2168923134655733 975.9738781290625 1695652.6832808387 0.05690503802354025 1.1971347778297898 1.7902218432004132e-05 4.7470931481776395 0.49019795383470655 AGSPFS(ph)PPPSSSSLTGEAAISR ddPTM_PC-9_AZD4547_30min_R2 1 AGSPFSPPPSSSSLTGEAAISR 22 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;A0A087WXJ0;C9J760;Q96JY6-2 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 AGS(0.011)PFS(0.988)PPPSSSSLTGEAAISR 133.93 1.9924e-05 24687000.0 20193.0 22540.0 22840.0 42498.0 29891.0 22240.0 21801.0 30127.0 23107.0 23210.0 True False 26613.953959507708 29825.61420627628 22537.126676609114 32700.74268755479 25741.150606217132 20849.329284234587 23741.24676586686 25471.564399588242 24328.38884612454 22397.424964574187 1.188259543300302 1.3316537170434188 1.0062374006054666 1.4600224239740627 1.1492906281383546 0.930880639949092 1.05999894199526 1.137254145950992 1.0862136555699837 1.0 14.45104525449361 -6.5234795405923 24.999999957739686 1.0511370063015253 1.2441077159167244 0.3970380928319037 0.11823130837092878 21.911016193111223 911691.651154964 0.03748987099128984 0.03781785630832093 2.995852722308944e-07 6.5234795405923 0.19297070961519913 AGSPFS(ph)PPPSSSSLTGEAAISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AGSPFSPPPSSSSLTGEAAISR 22 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;A0A087WXJ0;C9J760;Q96JY6-2 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 AGS(0.066)PFS(0.932)PPPS(0.001)SSSLTGEAAISR;AGS(0.38)PFS(0.62)PPPSSSSLTGEAAISR;AGS(0.004)PFS(0.996)PPPSSSSLTGEAAISR;AGS(0.018)PFS(0.981)PPPS(0.001)S(0.001)SSLTGEAAISR 150.13 3.6021e-05 28814000.0 40675.2 42238.0 51440.1 61734.7 68763.9 78968.7 89010.0 77598.3 87850.9 65764.3 True False 47560.707988180344 46431.10949878269 52666.627071665636 58275.904905597854 55290.107420786444 74827.44235554882 80578.32842340565 75561.4268471951 89135.55321492559 77686.84700008777 0.6122105584762194 0.5976701499898719 0.6779349285678454 0.7501386290723321 0.7117048709767302 0.9631931947947929 1.037219703656072 0.9726411839974628 1.1473699430075324 1.0 16.245382739134435 -6.696779909932888 1.0374757402441783 1.0602614548769707 0.6243418766710634 0.9072727806719912 0.057185153640583845 0.13916221759654324 0.3216222665112275 0.030403460342076537 0.029465370929244457 2.010111230877431e-07 6.696779909932888 -0.4359195782059072 AGSPFS(ph)PPPSSSSLTGEAAISR ddPTM_PC-9_Lapatinib_30min_R1 2 AGSPFSPPPSSSSLTGEAAISR 22 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;A0A087WXJ0;C9J760;Q96JY6-2 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 AGSPFS(0.996)PPPS(0.002)S(0.002)S(0.001)SLTGEAAISR;AGS(0.004)PFS(0.995)PPPSSSSLTGEAAISR 211.67 1.2659999999999999e-25 34193000.0 43837.0 40823.0 45296.0 41696.0 68299.0 74850.0 79255.0 68435.0 87322.0 74327.0 True False 43211.876341278774 40728.47685165765 41571.93772761639 44762.46293377849 64281.787101000424 71648.83998387211 83358.43610230676 71614.73993425042 77486.87681857483 87174.32291549777 0.49569500394245797 0.467207263440838 0.4768828289944282 0.513482197930793 0.7373935919561064 0.8219030281809558 0.9562269406222984 0.8215118573811007 0.888872711907227 1.0 16.41161563315714 -6.455541883460047 1.6356173591007679 0.9006196654729767 0.4721672832745357 0.9430837426067751 0.04769288037603001 0.07892597219668594 0.42514219906035017 0.017815115907425638 0.020592400307397233 3.503145022609986e-07 6.455541883460047 -0.42845238219844095 AGSPS(ph)RDVGPSLGLK ddPTM_PC-9_AZD4547_30min_R2 1 AGSPSRDVGPSLGLK 15 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 AGS(0.428)PS(0.572)RDVGPSLGLK 75.02 0.0072663 34874000.0 79170.0 38777.0 78370.0 125930.0 100720.0 73353.0 85809.0 104590.0 66508.0 88127.0 True False 104344.4131617008 51310.90692443548 77330.76259395175 96898.78409910519 86736.76655375156 68766.22531413929 93445.83476594044 88428.01873910241 70023.47710122699 85041.70055377124 1.2269793816708146 0.6033617224292449 0.9093275662456453 1.1394266985269985 1.019932174320862 0.8086177118560666 1.098823684821017 1.03981950223573 0.8234016564256222 1.0 16.375882825853587 -5.53850065415585 24.993364006532293 0.992538917281876 0.8754640349078597 0.030163108659331694 0.17203229765704647 585.8716995872823 937327.7112798698 0.04482198189710847 0.07766498021283692 2.894005457967455e-06 5.53850065415585 -0.11707488237401631 AGSPS(ph)RDVGPSLGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGSPSRDVGPSLGLK 15 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 AGS(0.15)PS(0.849)RDVGPS(0.001)LGLK;AGS(0.425)PS(0.575)RDVGPSLGLK 70.68 0.010957999999999999 78117000.0 111407.0 63411.0 97264.0 132973.0 131524.0 139991.0 139120.0 139274.0 114224.0 112788.0 True False 130266.00471145108 69706.02501130055 99583.1426357743 125522.95391428264 105752.81635293392 132649.62551992893 125941.54645842293 135618.20507300066 115894.30990942227 133235.57157068307 0.9777119066310561 0.523178789189347 0.7474215891582996 0.9421129240076191 0.7937280945789374 0.9956021800796397 0.9452546716595833 1.0178828632191035 0.8698451062518162 1.0 17.023619782652162 -6.082437949565667 1.2801052678591627 0.9582399269933687 0.7305548756898663 0.3132583128045179 0.12203768011741581 0.4928589361044204 1.6409866970811293 0.04471389902863377 0.07663671788776094 8.271076742973258e-07 6.082437949565667 -0.22768505130350236 AGSPS(ph)RDVGPSLGLK ddPTM_PC-9_Lapatinib_30min_R1 1 AGSPSRDVGPSLGLK 15 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 AGS(0.089)PS(0.911)RDVGPSLGLK 101.61 0.00077414 45002000.0 81780.0 68921.0 95660.0 85455.0 79458.0 81432.0 65902.0 59683.0 84949.0 67000.0 True False 80613.80220338465 68761.41765899347 87795.20405827828 91739.64576952333 74784.43666043848 77949.34318726354 69314.08309903741 62456.09006350346 75381.14906737267 78580.86072811161 1.0258706949304994 0.8750402708988739 1.1172593840890612 1.1674553436992867 0.9516876751858357 0.9919634687760279 0.8820733503907893 0.7948002794166436 0.9592812851489386 1.0 16.26189034985785 -6.944897684787025 2.051426023538603 0.8941960066078014 1.0351052909901308 0.27117958603573467 0.09060727199753531 0.4149834762946958 3.540613556915097 0.04074787609834575 0.03298836923766974 1.1352782437853088e-07 6.944897684787025 0.14090928438232941 AGSRLS(ph)AEER ddPTM_PC-9_Lapatinib_30min_R1 1 AGSRLSAEER 10 1 B1AJQ6;Q86Y82 B1AJQ6 STX12 Syntaxin-12 1 AGS(0.011)RLS(0.989)AEER 96.745 0.026124 6150200.0 56585.0 43861.0 44867.0 34439.0 38614.0 36826.0 30570.0 32491.0 50613.0 22551.0 True False 55778.087523581846 43759.44254931181 41178.208451628474 36971.75894513617 36342.8004380449 35251.03782559886 32152.765019841205 34000.650474227026 44912.43096148199 26448.910302681306 2.1088992659908277 1.6544894306997449 1.556896219178223 1.3978556591568951 1.3740755298474652 1.332797359973852 1.2156555658393857 1.2855217884262002 1.6980824709791127 1.0 14.690920663956703 -1.5228788283113037 0.6037694726518765 1.313166170153739 52.74592507841257 0.6907543974896241 0.16251802212405408 96.59133905026482 0.7385639835512086 0.07045013828266979 6561.214252157463 0.0299999942644246 1.5228788283113037 51.43275890825883 AGSS(ph)PAQGAQNEPPR ddPTM_PC-9_AZD4547_30min_R2 2 AGSSPAQGAQNEPPR 15 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 AGS(0.112)S(0.888)PAQGAQNEPPR;AGS(0.173)S(0.827)PAQGAQNEPPR 128.74 0.00027385 6796500.0 21499.1 22846.2 30909.0 35465.0 34831.0 34091.0 29541.0 32050.0 24977.4 33707.0 True False 28335.36659094002 30230.78736820894 30499.12646441817 27289.092178787963 29995.316876824076 31959.284380793208 32170.091771500036 27097.408935732146 26297.65437162726 32526.92818961231 0.8711356456952214 0.9294080028701679 0.9376577550338204 0.8389692386477158 0.9221687551301964 0.9825484962640775 0.9890295076119044 0.8330761754620863 0.8084887148988631 1.0 14.989346961692766 -4.7463368282422085 23.01428143860669 0.9133590551760967 0.8711353318515723 0.039812895016365535 0.06474753402006427 1305.9451286084097 1989772.0768106563 0.016814774349252007 0.33849245756772 1.7933422147050476e-05 4.7463368282422085 -0.0422237233245244 AGSS(ph)PAQGAQNEPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AGSSPAQGAQNEPPR 15 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 AGS(0.079)S(0.921)PAQGAQNEPPR;AGS(0.312)S(0.688)PAQGAQNEPPR;AGS(0.099)S(0.901)PAQGAQNEPPR 179.55 2.887e-05 13287100.0 33587.6 33149.3 52923.5 38282.5 48900.1 42816.4 37285.6 33299.5 42803.6 31647.6 True False 39273.31729466126 36440.14342790844 54185.396953491414 36137.65563853958 39318.476437305 40571.0326100356 33753.63804363258 32425.42340873667 43429.52167354455 37385.05935773625 1.050508357332172 0.974724771177011 1.4493864095545055 0.9666336301017925 1.0517163035925114 1.0852204946851332 0.9028643694435593 0.8673364163597814 1.1616812282673958 1.0 15.190174203217751 AGSS(ph)PAQGAQNEPPR ddPTM_PC-9_Lapatinib_30min_R1 3 AGSSPAQGAQNEPPR 15 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 AGS(0.073)S(0.927)PAQGAQNEPPR;AGS(0.23)S(0.77)PAQGAQNEPPR;AGS(0.055)S(0.945)PAQGAQNEPPR 147.83 0.00012478 24646800.0 59206.2 61972.0 205545.0 67030.0 99312.0 123999.0 72921.0 76731.0 155984.0 65344.0 True False 58361.90873091269 61828.50764154832 188645.8835266451 71959.60980552515 93470.66341490441 118695.85182578691 76696.49257480665 80296.20238028713 138415.43933566098 76638.62333459304 0.7615208388610155 0.8067538918544255 2.4614988542140788 0.9389470566474035 1.2196286852234433 1.5487732772492293 1.000755092376346 1.0477250097477042 1.8060794063504948 1.0 16.225784025615795 -5.048783052958059 24.999981819162993 1.3698101511933067 0.772818482793501 0.2201935972607434 0.44712056839079395 481.59868997433887 246805.9372807943 0.11053308664011814 0.2924562589741309 8.937518361593831e-06 5.048783052958059 -0.5969916683998058 AGSS(ph)TPGDAPPAVAEVQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGSSTPGDAPPAVAEVQGR 19 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 AGSS(0.5)T(0.5)PGDAPPAVAEVQGR;AGS(0.144)S(0.711)T(0.144)PGDAPPAVAEVQGR 248.01 7.1773e-54 58070000.0 78814.0 86659.9 92451.0 97841.0 108081.0 104231.2 114120.8 93299.4 87304.1 90708.8 True False 92155.65355254423 95262.92215667319 94655.38246237017 92359.28597480185 86903.30391595035 98765.13238345916 103310.45166095743 90850.38960888585 88580.75729936981 107153.5873895345 0.8600333017086175 0.8890315712003624 0.8833617685450911 0.861933680662029 0.8110162807711844 0.9217155933792411 0.9641343251103097 0.8478520581734535 0.8266709445513285 1.0 16.709320625174136 -6.8096638909332725 24.99953726002936 0.9058190908625148 0.8639137755649318 0.1943617980018928 0.050964978531265616 251.17576583670896 130207.47228867719 0.018485979058741685 0.016303145772655882 1.5500157425997338e-07 6.8096638909332725 -0.04190531529758301 AGSS(ph)TPGDAPPAVAEVQGR ddPTM_PC-9_Lapatinib_30min_R1 2 AGSSTPGDAPPAVAEVQGR 19 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 AGS(0.098)S(0.834)T(0.068)PGDAPPAVAEVQGR;AGSS(0.931)T(0.069)PGDAPPAVAEVQGR 323.02 6.291699999999999e-177 64435000.0 119439.0 109954.0 130684.0 94973.0 127849.0 125823.0 110141.0 119695.0 127155.0 95088.0 True False 117735.77795756984 109699.40826855352 119939.66597482798 101957.63124064029 120329.17318080513 120441.84359773857 115843.56205594791 125256.46666808077 112833.4648984895 111523.83410320454 1.0557005944452802 0.9836409333545447 1.0754621820465335 0.9142227942619722 1.0789547736446372 1.079965054701054 1.0387336750702625 1.1231363024352983 1.0117430574891555 1.0 16.76699254034864 AGSSGSS(ph)SGGGGGGPGGR ddPTM_PC-9_AZD4547_30min_R2 1 AGSSGSSSGGGGGGPGGR 18 0 P48634;P48634-2;P48634-3 P48634 PRRC2A Protein PRRC2A 1 AGS(0.059)S(0.059)GS(0.183)S(0.35)S(0.35)GGGGGGPGGR 95.755 0.00663 0.0 556.25 0.0 0.0 890.6 0.0 642.7 0.0 436.74 0.0 0.0 True False 733.1259292812434 0.0 0.0 685.2859296328365 0.0 602.5118674000705 0.0 369.25186828679136 0.0 0.0 0.0 AGSSPCLGSSSAAS(ph)SPPPPASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGSSPCLGSSSAASSPPPPASR 22 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 AGSSPCLGSSSAAS(0.625)S(0.375)PPPPASR 268.49 8.865799999999998e-186 0.0 7372.2 7184.5 8046.9 9286.8 10704.0 10184.0 9370.6 8438.7 11078.0 5741.5 True False 8620.167852412844 7897.729679293625 8238.76861403819 8766.490704211834 8606.62803930693 9649.933112092613 8482.948930731 8217.19306654173 11239.99479248303 6782.388500311004 1.2709634448126306 1.1644466663818325 1.2147296802093253 1.2925373861744798 1.2689671255063428 1.4227927391139743 1.2507317931348252 1.211548566727626 1.6572325209574217 1.0 12.727577710048608 -5.884248933747266 2.366655853160926 1.3154191217886577 1.209753586449626 0.05114136968392724 0.15839065801631394 0.8175227629341043 9.30570915727919 0.04601165602607157 0.07722131958511885 1.305422417086166e-06 5.884248933747266 -0.10566553533903167 AGSSPCLGSSSAASS(ph)PPPPASR ddPTM_PC-9_AZD4547_30min_R2 3 AGSSPCLGSSSAASSPPPPASR 22 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 AGSSPCLGSSSAAS(0.009)S(0.99)PPPPASR;AGSSPCLGSSSAAS(0.035)S(0.959)PPPPAS(0.007)R;AGSSPCLGSSSAAS(0.233)S(0.767)PPPPASR 229.37 3.6985e-42 31841000.0 94170.0 97575.0 125208.0 157558.0 143556.0 129520.0 108559.0 156731.0 116082.0 131169.0 True False 124114.10114231888 129114.21056687713 123547.66011054623 121235.43734683427 123625.72735693361 121421.09392509292 118220.54069335082 132511.82527008542 122217.85753390007 126576.81323473611 0.9805437344369687 1.0200463044320403 0.9760686570725057 0.9578013085382685 0.976685414947762 0.9592680588341095 0.9339825965922477 1.0468886195163 0.9655627631203483 1.0 16.949653625688484 -7.758109586753538 24.9999993898439 1.0046692607136194 0.973194542867677 0.22140947009257683 0.027516577347612113 135.0796580634104 1014200.6680961838 0.013785279299909034 0.007529691920198194 1.7453816802597506e-08 7.758109586753538 -0.03147471784594236 AGSSPCLGSSSAASS(ph)PPPPASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AGSSPCLGSSSAASSPPPPASR 22 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 AGSSPCLGS(0.001)S(0.009)S(0.009)AAS(0.064)S(0.916)PPPPASR;AGSSPCLGSSSAAS(0.007)S(0.993)PPPPASR;AGSSPCLGSSSAAS(0.026)S(0.974)PPPPASR;AGSSPCLGSSSAAS(0.028)S(0.972)PPPPASR 296.01 3.744099999999999e-132 36885400.0 109647.6 131304.4 131793.6 141712.3 170258.6 135705.6 151499.2 136680.7 133807.1 108728.0 True False 128208.77304118502 144339.4330714512 134936.05925401146 133772.6192684754 136897.64954158635 128588.95943994475 137148.0990167761 133092.97645017263 135763.77569933707 128439.5257096257 0.9982034138855171 1.123792946711527 1.0505804853178378 1.0415222146717256 1.0658529668747194 1.0011634559493539 1.067802907703339 1.0362306752133872 1.0570248912805076 1.0 16.970729717163472 -5.512421819223214 24.731155998117544 1.0412286124100392 1.0675453085048097 0.05119152208294697 0.035866767912367196 1025.415503006314 2425149.8361930302 0.008897402023560841 0.01666526949976577 3.0731105303532e-06 5.512421819223214 0.026316696094770498 AGSSPCLGSSSAASS(ph)PPPPASR ddPTM_PC-9_Lapatinib_30min_R1 2 AGSSPCLGSSSAASSPPPPASR 22 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 AGSSPCLGSSSAAS(0.025)S(0.975)PPPPASR;AGSSPCLGSSSAAS(0.114)S(0.884)PPPPAS(0.002)R 295.9 3.8070999999999986e-132 34149000.0 102918.0 95684.0 108896.0 100242.0 111889.0 112460.0 96697.0 106415.0 120971.0 91936.0 True False 101450.37044715043 95462.44957680766 99942.99123071595 107614.1310775093 105307.90900223778 107650.34795706418 101703.49751794517 111359.42938705713 107345.9720988962 107827.01510298021 0.9408622723188641 0.8853296132294511 0.9268826660486278 0.9980256893389139 0.976637523552548 0.998361568798438 0.9432098015586653 1.032760011771663 0.995538752476598 1.0 16.718359152270516 -5.691516151750221 4.684516841495704 0.9910939502231451 0.9118408714091354 0.658758764584604 0.024589710709960647 0.11794562520219219 4.90115157098736 0.0066420704293180845 0.011635336982068542 2.034622525246125e-06 5.691516151750221 -0.07925307881400967 AGSST(ph)PGDAPPAVAEVQGR ddPTM_PC-9_AZD4547_30min_R2 4 AGSSTPGDAPPAVAEVQGR 19 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 AGS(0.012)S(0.05)T(0.938)PGDAPPAVAEVQGR;AGS(0.012)S(0.05)T(0.938)PGDAPPAVAEVQGR;AGSS(0.002)T(0.998)PGDAPPAVAEVQGR;AGS(0.049)S(0.274)T(0.677)PGDAPPAVAEVQGR 264.0 6.747599999999998e-78 143888000.0 285212.0 268367.0 343091.0 477124.0 418774.0 358728.0 301392.0 417628.0 306673.0 360740.0 True False 375903.48322186456 355111.3845472828 338541.38916832267 367130.4332923172 360634.45866541617 336296.6814512097 328215.3041263311 353093.18873672234 322883.1086946617 348110.60240070993 1.0798392253194353 1.0201107984022684 0.9725109974634667 1.0546373214732299 1.035976658505477 0.9660627373368501 0.9428477669534542 1.0143132277547724 0.9275302345516933 1.0 18.40918622931423 -6.763104990635479 24.993133837129843 0.9693389226578635 1.029804678271391 0.4481680657454773 0.034580368265667676 43.731052140457024 656194.0557620735 0.011764468358486414 0.010924092509794056 1.7254207213279595e-07 6.763104990635479 0.060465755613527516 AGSST(ph)PGDAPPAVAEVQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AGSSTPGDAPPAVAEVQGR 19 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 AGSS(0.046)T(0.954)PGDAPPAVAEVQGR;AGS(0.011)S(0.047)T(0.942)PGDAPPAVAEVQGR;AGS(0.001)S(0.007)T(0.992)PGDAPPAVAEVQGR;AGS(0.002)S(0.049)T(0.949)PGDAPPAVAEVQGR 227.41 6.6701e-35 137210000.0 92047.4 73619.0 93849.0 102061.0 121539.0 110467.0 115434.0 88606.0 97801.0 81004.0 True False 107629.20680098033 80927.4077889789 96086.71608431438 96342.85305622627 97724.30542501176 104673.91605396064 104499.25585021262 86280.18638581714 99231.15460368615 95689.38397268896 1.1247768804917708 0.8457302621163982 1.004152311313226 1.0068290656330678 1.0212659060790232 1.0938926734426047 1.0920673904645275 0.9016693681552248 1.0370132033874109 1.0 16.546071256826004 -4.473808524608226 23.046838894243095 1.0028895205728656 2.772459517946158 0.20852546845387443 0.07259917309667727 428.72212715668894 320879.8346367494 0.01786527501004552 22251.10219380711 3.3588566969230006e-05 4.473808524608226 1.7695699973732923 AGSST(ph)PGDAPPAVAEVQGR ddPTM_PC-9_Lapatinib_30min_R1 2 AGSSTPGDAPPAVAEVQGR 19 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 AGSS(0.077)T(0.923)PGDAPPAVAEVQGR;AGSST(1)PGDAPPAVAEVQGR 319.45 1.1733999999999995e-156 67474000.0 68915.0 56099.0 66318.0 54986.0 62657.0 57080.0 51257.0 58976.0 72601.0 47059.0 True False 67932.25946253697 55969.10621221231 60865.590034883055 59029.85386791886 58971.638448401645 54638.82145997891 53910.836657572836 61716.24026247313 64423.910857577204 55193.08544782404 1.2308110501768508 1.0140601084011125 1.102775638307473 1.0695153820259213 1.068460622737781 0.98995772779601 0.9767679451176295 1.1181878991131173 1.1672460478492253 1.0 15.752199918020725 -4.752471575924106 24.959064811414866 1.0577056036441355 1.2308113897621278 0.44378545716263684 0.0585826096481769 349.8833594280347 973717.7807291574 0.015263757501168719 0.18202226560232235 1.7681879398206608e-05 4.752471575924106 0.17310578611799232 AGT(ph)GYASPDRTHVLAAGK ddPTM_PC-9_AZD4547_30min_R2 2 AGTGYASPDRTHVLAAGK 18 1 O43379;O43379-4 O43379 WDR62 WD repeat-containing protein 62 1 AGT(0.62)GY(0.243)AS(0.13)PDRT(0.007)HVLAAGK;AGT(0.477)GY(0.045)AS(0.457)PDRT(0.021)HVLAAGK 54.857 0.027129 77690000.0 78093.0 60862.0 91470.0 133928.0 129524.0 112536.0 77037.0 114399.0 85716.0 98786.0 True False 102924.94956469235 80534.45127872165 90257.04803456365 103052.96876697347 111541.8283469832 105499.10612997397 83893.1437595563 96721.26317749846 90246.77276731776 95327.53220811815 1.079698038757445 0.8448183794677451 0.9468098664037093 1.0810409792418545 1.1700903795921849 1.1067013242265553 0.880051563449703 1.0146204452910574 0.9467020773210815 1.0 16.540605328664476 -5.736698864773054 23.225669293974182 1.032045149167872 0.9458795309683834 0.10528508250809421 0.09320313461423273 215.7360927845945 202522.35347249717 0.026845350237956693 0.04645932962832449 1.8335853705041722e-06 5.736698864773054 -0.08616561819948854 AGT(ph)GYASPDRTHVLAAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGTGYASPDRTHVLAAGK 18 1 O43379;O43379-4 O43379 WDR62 WD repeat-containing protein 62 1 AGT(0.853)GY(0.115)AS(0.026)PDRT(0.005)HVLAAGK 53.828 0.028375 7714900.0 46938.0 31109.0 42732.0 62930.0 62380.0 66431.0 57113.0 55580.0 48938.0 47413.0 True False 54883.676332241994 34197.295927781386 43750.89294201248 59404.23612181271 50157.08679857686 62947.241414908094 51702.8431776876 54121.08389187781 49653.62566839994 56008.601578898495 0.9799151341946677 0.6105722150482218 0.7811459616677134 1.06062701883622 0.8955247120019825 1.123885254057544 0.9231232653587068 0.9662995034010666 0.886535715383888 1.0 15.773360787117449 -5.744499347055246 24.379999069597527 0.9782007813219022 0.7725470318535687 0.38883342467236026 0.10780425077956084 165.1298388324338 237651.20129667013 0.02779127466571951 0.04796116496107761 1.8009458420914648e-06 5.744499347055246 -0.2056537494683336 AGT(ph)PIRDSHSPDLQLPTPEVIPSSGSK ddPTM_PC-9_Lapatinib_30min_R1 1 AGTPIRDSHSPDLQLPTPEVIPSSGSK 27 1 H3BPE1;H3BQK9;H0Y6T5;H0Y4F5 H3BPE1 MACF1 1 AGT(0.333)PIRDS(0.333)HS(0.333)PDLQLPTPEVIPSSGSK 46.57 0.020123 6964900.0 49746.0 20330.0 41281.0 35491.0 32016.0 30193.0 33238.0 35792.0 46825.0 33809.0 True False 49036.612917700855 20282.927134071484 37887.03552926816 38101.12653450531 30132.881825877816 28901.715773320633 34958.901005216976 37455.026985119985 41551.07541089038 39652.84060233923 1.2366481738210717 0.5115125884039424 0.9554683839480872 0.960867518082869 0.7599173569446672 0.7288687351093742 0.8816241276584521 0.9445736148070665 1.0478713448952548 1.0 15.275136599226906 -7.898496964303138 2.6322935357967734 1.020212816174596 0.8457376917051558 0.11592542159037889 0.17692260432311643 0.56436575506035 7.624796585883695 0.11921627149842413 0.046646161243852784 1.2632899341103995e-08 7.898496964303138 -0.17447512446944025 AGT(ph)PVSELTK ddPTM_PC-9_AZD4547_30min_R2 3 AGTPVSELTK 10 0 O75113 O75113 N4BP1 NEDD4-binding protein 1 1 AGT(0.999)PVS(0.001)ELTK;AGT(1)PVSELTK;AGT(0.964)PVS(0.004)ELT(0.032)K 126.71 0.00082435 46961000.0 390957.0 435440.0 335587.0 376026.0 416400.0 434700.0 477270.0 439270.0 383273.0 459190.0 True False 515273.1935892273 576187.4645066973 331136.89711134956 289339.01524378726 358590.0475871939 407518.14028132946 519746.10540549725 371390.9149204077 403532.02831266297 443113.8978665579 1.1628459320957698 1.3003145856648668 0.7472952184656375 0.6529675928398 0.8092502837615397 0.9196690562931792 1.1729402032026015 0.83813871943202 0.9106733737206888 1.0 18.75731805079515 -5.2554478562996065 24.997614531326466 0.8766346127744432 1.231580288345863 0.5101561307185813 0.13720556584298674 411.9662717799126 1718778.2343343785 0.03858353519802314 0.09667680800784763 5.553312891388242e-06 5.2554478562996065 0.35494567557141987 AGT(ph)PVSELTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AGTPVSELTK 10 0 O75113 O75113 N4BP1 NEDD4-binding protein 1 1 AGT(1)PVSELTK;AGT(0.999)PVS(0.001)ELTK;AGT(1)PVSELTK;AGT(0.999)PVSELTK 142.89 0.00031237 51837100.0 447399.0 544903.0 334140.0 470861.0 479811.0 358570.0 462644.0 357126.0 283237.0 314125.0 True False 523134.81416696036 598997.3687015283 342107.16483300645 444480.1847219587 385795.47890208376 339765.9579735911 418819.0110674989 347751.8209062755 287378.8052932404 371073.3758878685 1.4097880585349298 1.6142289035647068 0.9219393981431449 1.197822893271309 1.0396743716225656 0.915630115366353 1.1286689864649795 0.9371510959906744 0.7744527739443127 1.0 18.50134496738154 -5.263160915202915 24.99969628810525 0.9987487904857666 1.5120085065309632 0.7492608632075507 0.12082867330251737 68.17261072492413 990002.882954592 0.031654284588160095 0.07192427634802522 5.455556838292592e-06 5.263160915202915 0.5132597160451966 AGT(ph)PVSELTK ddPTM_PC-9_Lapatinib_30min_R1 2 AGTPVSELTK 10 0 O75113 O75113 N4BP1 NEDD4-binding protein 1 1 AGT(0.998)PVS(0.002)ELTK;AGT(1)PVSELTK 136.53 0.00028246 30340000.0 143382.0 227520.0 197252.0 218070.0 230905.0 191199.0 198417.0 203820.0 155447.0 166213.0 True False 141337.34638696144 226993.19141878746 181034.70197473897 234107.5952601947 217323.6218766966 183021.86447663791 208690.06139816277 213290.22128149171 137938.9219305218 194942.69558509893 0.7250199652916106 1.1644098320149545 0.9286559900661235 1.2009046789752582 1.1148077193886325 0.9388495625718011 1.0705200354996767 1.0941175335722362 0.7075870245690068 1.0 17.572690573052434 -8.242800742767358 24.866970235246445 0.8537934647247212 1.0376667956341206 0.18547238206606753 0.1466547264491361 1003.385114255769 1338684.0475124915 0.09334832696180795 0.03514209340582151 5.717408950768144e-09 8.242800742767358 0.1838733309093994 AGTDS(ph)PVSCASVTEER ddPTM_PC-9_AZD4547_30min_R2 3 AGTDSPVSCASVTEER 16 0 E9PEI0;Q69YH5 E9PEI0 CDCA2 Cell division cycle-associated protein 2 1 AGT(0.225)DS(0.775)PVSCASVTEER;AGT(0.17)DS(0.829)PVS(0.001)CASVTEER;AGTDS(0.999)PVSCASVTEER 233.28 7.133399999999999e-37 29795200.0 40385.6 39832.7 47847.4 65832.0 56533.5 43728.6 38462.4 58833.0 40314.9 45560.3 True False 53227.38072733592 52707.84130409674 47212.9122130642 50655.44949426109 48684.79936424259 40994.24372925269 41885.479088458174 49741.71169784494 42445.86330950045 43965.24776447604 1.2106694135440241 1.198852365997235 1.073868899044674 1.1521702269398046 1.1073473217994683 0.9324238077506316 0.9526951676205879 1.131387043792263 0.9654412397920511 1.0 15.424075978573818 -5.956901665334507 0.8611184758025491 1.0038724560590837 1.207054803955064 0.5786924502129172 0.06385440759396697 0.5641783791948793 0.8285225780902592 0.031322717410339616 0.07763449170143666 1.1043286380315946e-06 5.956901665334507 0.20318234789598022 AGTDS(ph)PVSCASVTEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AGTDSPVSCASVTEER 16 0 E9PEI0;Q69YH5 E9PEI0 CDCA2 Cell division cycle-associated protein 2 1 AGT(0.117)DS(0.882)PVSCASVTEER;AGTDS(0.943)PVS(0.049)CAS(0.007)VTEER;AGT(0.003)DS(0.992)PVS(0.005)CASVTEER 195.5 8.2563e-12 23601400.0 61164.0 54766.0 64737.0 61059.0 74537.0 56626.0 62736.0 56218.0 48615.7 40747.9 True False 71517.85715593425 60202.8065441151 66280.57559643958 57638.06218594891 59932.009918331474 53656.43287562415 56793.191910692956 54742.3370678947 49326.61264063164 48135.17170980106 1.4857713105731398 1.2507030598554378 1.3769676775234985 1.1974209323161698 1.2450773060424836 1.1147032610397622 1.1798688961387664 1.1372627358208494 1.0247519825630533 1.0 15.554803816341694 -1.5228787452803376 0.16584431608382807 0.9582657841979593 2.8605047259409355 0.8208227438567226 0.05984852230355264 23.744671225210205 0.25246689890655644 0.15423383878936744 11.131298392339055 0.029999999999999995 1.5228787452803376 1.9022389417429761 AGTDS(ph)PVSCASVTEER ddPTM_PC-9_Lapatinib_30min_R1 4 AGTDSPVSCASVTEER 16 0 E9PEI0;Q69YH5 E9PEI0 CDCA2 Cell division cycle-associated protein 2 1 AGTDS(1)PVSCASVTEER;AGTDS(1)PVSCASVTEER;AGT(0.001)DS(0.999)PVSCASVTEER;AGT(0.009)DS(0.991)PVSCASVTEER 279.29 1.1659999999999998e-82 42506500.0 67981.0 63617.6 81973.0 60542.3 78692.0 70437.4 56790.8 59357.8 75070.8 52583.0 True False 67011.57847381129 63470.297355853654 75233.49636493054 64994.782705192294 74063.49127442454 67424.95659959914 59731.149744481474 62115.78008430256 66615.53597343028 61671.90148755669 1.086582006674984 1.0291607008202888 1.2198990877573335 1.05387998646849 1.2009276427023747 1.0932848667428103 0.9685310214820149 1.007197420316859 1.0801602409951807 1.0 15.912325708180562 -7.097394232376214 6.137565707335785 1.0154082472374224 1.1181983462236584 0.3979349316688171 0.06082160402612626 0.2479977826236721 12.985941224890864 0.02298818755753493 0.017809011026318305 7.991085320271799e-08 7.097394232376214 0.10279009898623603 AGTDSPVS(ph)CASVTEER ddPTM_PC-9_AZD4547_30min_R2 1 AGTDSPVSCASVTEER 16 0 E9PEI0;Q69YH5 E9PEI0 CDCA2 Cell division cycle-associated protein 2 1 AGT(0.001)DS(0.256)PVS(0.411)CAS(0.332)VTEER 195.6 8.1416e-12 5742400.0 8541.0 8415.2 9713.3 14600.0 10772.0 13457.0 7674.4 10516.0 6744.3 10928.0 True False 11256.860336163785 11135.248831794857 9584.495295442523 11234.195567751414 9276.493738254692 12615.531662677366 8357.406732717242 8890.99383363992 7100.7899292386655 10545.414046224321 1.0674649934863571 1.0559328237834076 0.9088780443736255 1.0653157399517854 0.8796708879890826 1.1963050106310646 0.7925157510253973 0.843114722159558 0.6733533551279602 1.0 13.364328120551855 -7.29585358395775 24.849191851515464 0.8141721234959002 1.0195682085635212 0.4365511615060347 0.11155151952057932 526.1072291485616 379879.93910234055 0.04380753904411645 0.029536535473659455 5.059952221502926e-08 7.29585358395775 0.20539608506762097 AGTEDEEEEEEGRR ddPTM_PC-9_AZD4547_30min_R2 2 AGTEDEEEEEEGRR 14 1 F8WBH7;O95456-2;O95456 F8WBH7 PSMG1 Proteasome assembly chaperone 1 0 ; 101.56 0.0010632999999999999 8254500.0 18422.1 18517.7 16701.7 23427.0 18681.8 24234.3 20211.5 25662.0 26628.0 21465.8 False True 24279.94459651596 24503.184391639854 16480.224545303085 18026.267093541956 16088.154541341117 22718.925389969685 22010.284345136348 21696.52755409544 28035.501717860574 20714.288875681003 1.1721350774933486 1.1829121694062639 0.7955969255913585 0.8702334510119322 0.7766694110474117 1.096775541092418 1.0625652889767734 1.0474184117209837 1.353437807405246 1.0 14.338338672802195 -7.458902892108926 1.6134043760112988 1.1543409593435148 0.9648880883983867 0.16933116799331993 0.15765884408564418 0.7082236639579458 3.5748630917530204 0.10716214941270023 0.05476814106466929 3.476138789332181e-08 7.458902892108926 -0.18945287094512808 AGTEDEEEEEEGRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGTEDEEEEEEGRR 14 1 F8WBH7;O95456-2;O95456 F8WBH7 PSMG1 Proteasome assembly chaperone 1 0 ; 104.94 0.0006448 6898200.0 18798.4 21240.0 23249.9 17283.2 20535.2 16427.2 20446.8 14965.0 20113.1 16865.1 False True 21980.597834675915 23348.56682973021 23804.26579173676 16314.878336890426 16511.47497316663 15565.728713567141 18509.93108198733 14572.18460672816 20407.216037253143 19922.609125941846 1.1032991560354561 1.1719633047122988 1.1948367626577832 0.818912735463264 0.8287807519983177 0.7813097478933381 0.9290917150949359 0.7314395677096966 1.024324470165922 1.0 14.282118979092129 -5.761054269266501 24.999764174665216 0.858841595300842 1.158226147933698 0.6720000843670584 0.09029499396532155 5.216975650625142 338614.43825991335 0.023400692263455473 0.037533922663262914 1.733587355829099e-06 5.761054269266501 0.2993845526328559 AGTEDEEEEEEGRR ddPTM_PC-9_Lapatinib_30min_R1 2 AGTEDEEEEEEGRR 14 1 F8WBH7;O95456-2;O95456 F8WBH7 PSMG1 Proteasome assembly chaperone 1 0 ; 102.62 0.00089605 8913200.0 6464.0 8970.2 10765.1 7514.5 9159.3 9686.099999999999 11372.400000000001 10826.3 8976.0 8635.6 False True 6371.822174647582 8949.430053027445 9880.035032487702 8067.141397637145 8620.567981876648 9271.848082401919 11961.207226419443 11329.329421351267 7965.028358529679 10128.251953786288 0.6291137112032028 0.8836105276470577 0.9754926198093054 0.7964988859327666 0.8511407517517358 0.9154440593211925 1.1809744940189737 1.1185868472709128 0.7864168856455115 1.0 13.306097578839557 -7.022959092997593 6.4768575695729576 1.034251124467671 0.8407470755708994 0.3422338517631376 0.12575608653800113 0.2095590183634955 33.85121792599917 0.04782587610578965 0.03852947233417683 9.485078008016343e-08 7.022959092997593 -0.19350404889677164 AGTFIAPPVYS(ph)NITPYQSHLRSPVR ddPTM_PC-9_AZD4547_30min_R2 1 AGTFIAPPVYSNITPYQSHLRSPVR 25 1 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 AGTFIAPPVY(0.39)S(0.456)NIT(0.033)PY(0.106)QS(0.012)HLRS(0.003)PVR 61.61600000000001 0.0010373 14647000.0 24581.0 14913.0 36636.0 49059.0 40010.0 32875.0 22742.0 34782.0 25428.0 35170.0 True False 32397.246683437774 19733.33561039034 36150.18270246282 37749.205503994315 34455.30212287132 30819.321053022108 24765.993942908288 29407.24111084668 26772.07216770913 33938.70900491487 0.9545809971365184 0.5814403726297496 1.0651608078912989 1.1122758234123644 1.015221354409257 0.9080876072380648 0.7297270482304373 0.866480840699864 0.7888359030931938 1.0 15.050644066774435 -7.0140033633572445 23.46192357970769 0.832816187631443 0.9434112098491361 0.08772109407364148 0.1487575014647668 743.2363569672141 1245253.5743708382 0.058693164151937705 0.047440323280607516 9.682703575435177e-08 7.0140033633572445 0.11059502221769302 AGTFIAPPVYS(ph)NITPYQSHLRSPVR ddPTM_PC-9_Lapatinib_30min_R1 1 AGTFIAPPVYSNITPYQSHLRSPVR 25 1 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 AGTFIAPPVY(0.111)S(0.595)NIT(0.033)PY(0.157)QS(0.074)HLRS(0.031)PVR 50.055 0.010825 15157000.0 44937.0 30341.0 47856.0 36393.0 44945.0 47738.0 41458.0 40034.0 54414.0 34757.0 True False 44296.19013956347 30270.747278645475 43921.46440950214 39069.46262348908 42301.4234652698 45696.35702271326 43604.492384448036 41894.125791302366 48285.32231517757 40764.70113920865 1.0866310533786334 0.7425725304663208 1.0774386462325178 0.9584140575462471 1.0376973774642269 1.1209785855331882 1.0696629968055376 1.0277059470701577 1.1844885640222533 1.0 15.31503281768534 -6.0565559304006635 1.230799959788345 1.0818290535829784 0.9328032408976193 0.214142844621952 0.10024542469332715 0.6324302176765931 1.950861678511925 0.036162092879323975 0.06488379124736847 8.778980201524933e-07 6.0565559304006635 -0.14902581268535908 AGTFIAPPVYSNITPYQS(ph)HLRSPVR ddPTM_PC-9_AZD4547_30min_R2 1 AGTFIAPPVYSNITPYQSHLRSPVR 25 1 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 AGTFIAPPVY(0.001)SNITPY(0.38)QS(0.473)HLRS(0.145)PVR 78.057 5.5919e-05 13227000.0 49676.0 46058.0 98667.0 159530.0 118140.0 92003.0 78992.0 97624.0 63596.0 87955.0 True False 65471.93467501132 60945.347786720195 97358.61111212752 122752.82321393046 101738.30024483906 86250.03786589178 86022.13497221922 82538.45397634686 66957.55472619274 84875.72222141824 0.7713858917655205 0.7180539521976609 1.1470725498882322 1.446265433756203 1.1986737500675497 1.0161920936694748 1.0135069572404969 0.9724624641310967 0.7888893664023058 1.0 16.373064325087384 -7.792085599105791 2.2094057696807266 0.8939408050436307 1.0609709239538467 0.07904750054566134 0.2006721924657589 0.8945694460046684 8.588191813213077 0.16022805530886053 0.06588251704730627 1.6140403993614405e-08 7.792085599105791 0.16703011891021602 AGTFIAPPVYSNITPYQS(ph)HLRSPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AGTFIAPPVYSNITPYQSHLRSPVR 25 1 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 AGTFIAPPVY(0.003)S(0.003)NIT(0.012)PY(0.307)QS(0.338)HLRS(0.338)PVR;AGTFIAPPVYS(0.001)NIT(0.004)PY(0.165)QS(0.653)HLRS(0.176)PVR;AGTFIAPPVY(0.051)S(0.012)NIT(0.014)PY(0.289)QS(0.317)HLRS(0.317)PVR 84.03 5.3662e-06 36723000.0 123824.0 88040.0 130000.0 167594.0 214804.0 218735.0 225488.0 240239.0 216035.0 174005.0 True False 144784.9575645219 96780.02936390982 133099.6930277456 158204.25152707877 172714.69818341598 207264.15153903948 204128.14424825198 233932.98080426102 219194.10317693395 205550.72907717826 0.7043757918764638 0.47083281970540597 0.6475272241810954 0.7696603764790234 0.8402533961266889 1.0083357644585045 0.993079154545873 1.138079061331989 1.0663747297857211 1.0 17.649134963508033 -6.338501644693466 1.0142604871111316 1.0701178733785157 0.5750336696171782 0.8839610495196588 0.06884479282462795 0.1554675958425233 0.3393505631312737 0.031442549655934536 0.04471990431769591 4.586679087981419e-07 6.338501644693466 -0.49508420376133755 AGTFIAPPVYSNITPYQS(ph)HLRSPVR ddPTM_PC-9_Lapatinib_30min_R1 1 AGTFIAPPVYSNITPYQSHLRSPVR 25 1 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 AGTFIAPPVYSNIT(0.001)PY(0.134)QS(0.432)HLRS(0.432)PVR 99.75299999999999 7.917e-07 11117000.0 94363.0 50322.0 78659.0 54604.0 78577.0 87955.0 67813.0 76668.0 105780.0 62024.0 True False 93017.36631594531 50205.48250077446 72191.96065252069 58619.76031360417 73955.25534832591 84193.3696831191 71324.02532844275 80230.27517029441 93865.94248721811 72744.76575821485 1.2786812267031205 0.6901593809188244 0.992400757636205 0.8058278791967162 1.0166402294033692 1.157380449377712 0.9804695167416678 1.102901003722515 1.290346343257255 1.0 16.150555824321778 -6.521184376544425 8.226736204544329 1.1030851345188721 0.925287645945101 0.1839557896353714 0.1620581706124752 0.17775924085227793 120.20653984663714 0.049843109089641804 0.052170341342631064 3.0117271460140444e-07 6.521184376544425 -0.1777974885737711 AGTFIAPPVYSNITPYQSHLRS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 1 AGTFIAPPVYSNITPYQSHLRSPVR 25 1 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 AGTFIAPPVYSNITPY(0.001)QS(0.155)HLRS(0.844)PVR 107.32 2.4171e-07 13504000.0 24802.0 22901.0 36293.0 64803.0 53051.0 41678.0 29122.0 42428.0 28794.0 38677.0 True False 32688.520086352208 30303.300396536506 35811.73110657508 49863.66954636954 45685.78437691697 39071.86807141766 31713.801583210592 35871.727498447566 30315.992055883933 37322.930002362584 0.8758294186518312 0.811921796992312 0.9595101752276188 1.3360062980910963 1.224067466675982 1.0468596133514803 0.8497136098694039 0.9611176693838572 0.8122618469119358 1.0 15.187774627634932 -7.2456649832256 21.921071462198082 0.902533106544571 1.049731425420525 0.16115811584041007 0.15203965339347356 330.0316701033171 458632.2742104421 0.06667155619990027 0.0513722202270433 5.679825808516756e-08 7.2456649832256 0.14719831887595403 AGTFIAPPVYSNITPYQSHLRS(ph)PVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGTFIAPPVYSNITPYQSHLRSPVR 25 1 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 AGTFIAPPVY(0.006)S(0.007)NIT(0.001)PY(0.298)QS(0.05)HLRS(0.638)PVR 62.67 0.00085926 7774600.0 18208.0 10912.0 19871.0 21173.0 27842.0 26231.0 27226.0 28838.0 27983.0 24191.0 True False 21290.25477560743 11995.271245104335 20344.800001187155 19986.74545379218 22386.559965469307 24855.400182963625 24646.95618082961 28081.0330563867 28392.198436365095 28576.63680414936 0.7450231082657026 0.4197579766756391 0.7119382221435193 0.6994085969868253 0.7833867966652659 0.8697804557376952 0.8624862453110943 0.9826570302460961 0.9935458336455645 1.0 14.80254851461562 -6.586980074272909 0.634575177368248 1.005421721509999 0.5689256075972724 0.7599700207434182 0.08269366856952812 0.3686528828753172 0.3281009942754893 0.05937188274121005 0.07757830833913158 2.588331666851414e-07 6.586980074272909 -0.4364961139127266 AGTFIAPPVYSNITPYQSHLRS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 1 AGTFIAPPVYSNITPYQSHLRSPVR 25 1 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 AGTFIAPPVYSNIT(0.004)PY(0.005)QS(0.298)HLRS(0.692)PVR 67.658 0.00032219 7207200.0 46363.0 34422.0 39591.0 34784.0 42739.0 46705.0 31692.0 35742.0 46143.0 26175.0 True False 45701.8551180671 34342.29797388138 36335.98080567953 37342.131396022414 40225.17604810694 44707.536024672634 33332.85668985307 37402.70380258603 40945.88943266878 30699.31387400483 1.4886930472008342 1.1186666293203806 1.1836088895930552 1.2163832569444655 1.3102956050808776 1.4563040792429405 1.0857850708539203 1.2183563436008062 1.3337721357785919 1.0 14.905918791443526 -11.476514659821534 2.450092672050647 0.8001923832062193 1.2595586790056477 0.28740444536537757 0.1259647349355031 23698757.685543556 10727654.846337683 26943152.669397756 0.03125043914737149 3.3379923742015366e-12 11.476514659821534 0.45936629579942834 AGTGYAS(ph)PDR ddPTM_PC-9_AZD4547_30min_R2 1 AGTGYASPDR 10 0 O43379;O43379-4 O43379 WDR62 WD repeat-containing protein 62 1 AGTGYAS(1)PDR 95.477 0.005901600000000001 8141600.0 18672.0 23375.0 24451.0 33868.0 37737.0 31365.0 33258.0 35486.0 34043.0 26527.0 True False 24609.30759827306 30930.51162696133 24126.76376400042 26060.255855383908 32497.86893803537 29403.741591727427 36217.89757071693 30002.45408715728 35842.443479838075 25598.297804190406 0.9613650011620909 1.2083034529701444 0.942514379219813 1.0180464363188195 1.2695324191718527 1.1486600326570962 1.414855700475057 1.172048794675946 1.4001885498015698 1.0 14.643760258872357 -6.261218353005375 24.99989297701719 1.2475710556195925 1.0386789673420562 0.35783001074535337 0.13151434651046598 20.813690683074984 2354143.389519112 0.03744804013326984 0.045372108264021965 5.480013735020655e-07 6.261218353005375 -0.20889208827753625 AGTGYAS(ph)PDR ddPTM_PC-9_Lapatinib_30min_R1 1 AGTGYASPDR 10 0 O43379;O43379-4 O43379 WDR62 WD repeat-containing protein 62 1 AGTGYAS(1)PDR 77.67399999999999 0.021442 8630100.0 31855.0 41725.0 48491.0 46313.0 63793.0 47641.0 46446.0 59175.0 52030.0 41420.0 True False 31400.741858508434 41628.388326076376 44504.25716067304 49719.01251563902 60040.82116186355 45603.505486595226 48850.74661797662 61924.486528958325 46169.833499810484 48579.39181131921 0.6463798884199271 0.8569145634379222 0.9161139220006322 1.0234589331366284 1.2359319234596464 0.9387417953628931 1.0055858008208778 1.274706912129963 0.9503995784700768 1.0 15.568056807845867 -4.897969858813052 1.0133474074976832 1.0750133452878878 0.49266872605113154 0.5914592781541005 0.10850425278375322 1.095918654880299 1.0333158707650645 0.03592839176571848 0.66707989967483 1.2648241265683904e-05 4.897969858813052 -0.5823446192367563 AGTLSITEFADMLSGNAGGFRS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 AGTLSITEFADMLSGNAGGFRSR 23 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 AGTLSITEFADMLS(0.037)GNAGGFRS(0.963)R 63.108999999999995 0.010999 0.0 17033.0 5228.2 16229.0 10866.0 9795.8 9257.1 6953.0 6671.7 14279.0 6977.3 True False 16790.106296530354 5216.09442411965 14894.714265751643 11665.121887913401 9219.63030328379 8861.195412354078 7312.992318709716 6981.691538238299 12670.748655464045 8183.317008332144 2.051748243338843 0.637405885511791 1.8201316471775497 1.4254759868200304 1.1266373151494051 1.082836630101428 0.8936464652736446 0.8531615640857654 1.5483634133399524 1.0 12.998470025320797 -6.304609473674456 3.9369183417073557 1.060951252364899 1.449785117660828 0.2049658332941816 0.3837913582623278 0.3892154379472217 12.993701352337576 0.11632712617516473 0.13771516331739875 4.95895909942509e-07 6.304609473674456 0.3888338652959291 AGTPIRDS(ph)HSPDLQLPTPEVIPSSGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGTPIRDSHSPDLQLPTPEVIPSSGSK 27 1 H3BPE1;H3BQK9;H0Y6T5;H0Y4F5 H3BPE1 MACF1 1 AGT(0.238)PIRDS(0.598)HS(0.162)PDLQLPT(0.001)PEVIPSSGSK;AGT(0.002)PIRDS(0.499)HS(0.499)PDLQLPTPEVIPSSGSK 88.244 2.7101999999999995e-07 10220500.0 39222.0 27409.6 35536.0 59914.0 53153.0 57936.0 54362.0 65180.0 54765.0 44720.0 True False 45861.50993018865 30130.64394426425 36383.31301103049 56557.21282380878 42738.05121200311 54897.734169500996 49212.437813202785 63469.09406391857 55565.83451979899 52827.381996674776 0.8681389877142768 0.570360347332011 0.688720728453298 1.070604120177085 0.8090132351191143 1.0391908910601804 0.931570635400794 1.2014431089527329 1.0518377481453953 1.0 15.68899829456935 -6.09907836248242 0.8171648173560759 1.0650948943538125 0.6789822341048184 0.5038198098917152 0.12808932012566687 0.5574267289042837 0.7696699338037294 0.06502676690382199 0.13618861242430985 7.960157073423626e-07 6.09907836248242 -0.38611266024899416 AGTPIRDSHSPDLQLPT(ph)PEVIPSSGSK ddPTM_PC-9_Lapatinib_30min_R1 1 AGTPIRDSHSPDLQLPTPEVIPSSGSK 27 1 H3BPE1;H3BQK9;H0Y6T5;H0Y4F5 H3BPE1 MACF1 1 AGT(0.012)PIRDS(0.036)HS(0.111)PDLQLPT(0.842)PEVIPSSGSK 72.082 8.4515e-05 5667700.0 44490.0 25990.0 34246.0 29773.0 30756.0 34814.0 17744.0 22996.0 34665.0 22673.0 True False 43855.564441533206 25929.82175182085 31430.426073382885 31962.605739816452 28946.992548622515 33325.08637539776 18662.697497941197 24064.478111025364 30760.662661367118 26591.99784012654 1.64920156451564 0.975098670950308 1.181950534982193 1.2019633098640607 1.0885602775186134 1.2531998000207112 0.7018162986528127 0.9049518676897896 1.1567638823642723 1.0 14.698704549590785 -7.232906128819912 24.780050695820037 0.932962275948413 1.2044316273609341 0.3370730717382977 0.19378447116681438 767.9567903224731 666942.2729991173 0.0719004293664778 0.05568302410813552 5.849164980656526e-08 7.232906128819912 0.27146935141252115 AGTQIENIDEDFRDGLK ddPTM_PC-9_AZD4547_30min_R2 4 AGTQIENIDEDFRDGLK 17 1 O43707;F5GXS2;O43707-3;K7EP19 O43707 ACTN4 Alpha-actinin-4 0 ;;; 174.4 8.0503e-06 25633700.0 81726.5 75609.2 94237.0 123222.0 120331.0 109783.0 80975.7 106830.6 93975.9 107151.0 False True 107713.82698319749 100048.39528150769 92987.35580663811 94815.07166092237 103625.11771425232 102918.25165517631 88182.38042928341 90322.38549296823 98943.27421839761 103399.67610422606 1.041723059892594 0.9675890587960807 0.8993002619554397 0.9169764861289268 1.002180293193559 0.9953440429681377 0.8528303351781902 0.8735267739322894 0.9569012007219787 1.0 16.657872140906306 -7.24204974847705 24.943957039794878 0.9102751313547155 0.9661538944471829 0.15346302049504879 0.054429259329171566 1380.49036144612 1775945.8945131316 0.021540256005627686 0.016659470983280064 5.727304209001454e-08 7.24204974847705 0.05587876309246742 AGTQIENIDEDFRDGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AGTQIENIDEDFRDGLK 17 1 O43707;F5GXS2;O43707-3;K7EP19 O43707 ACTN4 Alpha-actinin-4 0 ;; 162.26 3.9983e-05 17897900.0 56382.0 47566.6 46153.5 58826.7 67384.5 58117.5 60628.7 59033.8 52139.5 46359.1 False True 65926.35900473957 52288.69769129211 47253.97447812345 55530.83071773463 54180.99094868062 55069.7159899885 54885.510622223774 57484.22530148142 52901.94154925698 54763.637851566324 1.2038345440715454 0.9548068708112051 0.8628713564683671 1.0140091655022578 0.9893606976135345 1.0055890760809534 1.0022254323386584 1.0496787203452242 0.9660048825215856 1.0 15.740930665007431 -6.888423497047659 5.449758101313954 1.00799324835768 0.9948264125349411 0.0 0.08166716736769625 2.3781212127207976 104.7447379201229 0.02985660957903309 0.026310311781990055 1.2929344370415878e-07 6.888423497047659 -0.01316683582273881 AGTQIENIDEDFRDGLK ddPTM_PC-9_Lapatinib_30min_R1 4 AGTQIENIDEDFRDGLK 17 1 O43707;F5GXS2;O43707-3;K7EP19 O43707 ACTN4 Alpha-actinin-4 0 ;;; 211.57 6.917100000000001e-18 34182500.0 110782.0 99363.0 113671.0 108486.0 113200.0 113341.0 110990.0 107009.0 115323.0 102547.0 False True 109202.22836506911 99132.93107834454 104325.40916274911 116464.42233868709 106541.79855976294 108493.66964077544 116736.51912175921 111981.02879556068 102334.10933497296 120272.1123147117 0.9079596779619499 0.8242387131186901 0.8674114651762711 0.9683410401402016 0.8858395891557875 0.9020683810465052 0.9706033832373291 0.9310639568925501 0.8508548437828961 1.0 16.87594263574215 -10.884469021713224 0.01383817590368625 1.941648103876984 2.6549963204872364e-06 0.29056074288638656 0.045304167428068955 3921.2302296245325 9.101972134560981 700.1908238700089 580.537731363715 1.3047610341096423e-11 10.884469021713224 -1.9416454488806634 AGTQIENIEEDFR ddPTM_PC-9_Lapatinib_30min_R1 2 AGTQIENIEEDFR 13 0 P12814-4;P12814-3;P12814;P12814-2;P35609-2;P35609;A0A494C1A0;Q08043;G3V2N5;A0A087WSZ2;A0A494C033;A0A494C166;G3V5M4;A0A494C0Q3;G3V380 P12814-4 ACTN1;ACTN2;ACTN3 Alpha-actinin-1;Alpha-actinin-2;Alpha-actinin-3 0 ; 139.46 0.00029475 3856800.0 11773.2 14163.0 13188.900000000001 10577.7 14527.9 10875.8 13123.2 14517.0 13107.8 13480.5 False True 11605.312009059544 14130.206443672127 12104.559552626268 11355.619344172792 13673.397484950348 10410.667386728075 13802.655083689244 15191.51281691403 11631.461532746805 15810.586463362844 0.7340216022948932 0.8937180462227264 0.7655983907159684 0.7182288506809443 0.8648254456996325 0.6584618104364593 0.8730008286329866 0.9608443590702113 0.7356755272614247 1.0 13.94860326224213 -9.73569171603548 0.35273900607151176 1.0487139414557707 0.7786613118210833 0.31668294802762154 0.08918504540841075 7.60516486909545 1.1507937026708646 0.5890073243884817 0.07650386185929366 1.8378424730171065e-10 9.73569171603548 -0.27005262963468735 AGTTATY(ph)EGR ddPTM_PC-9_AZD4547_30min_R2 1 AGTTATYEGR 10 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 AGT(0.01)T(0.059)AT(0.059)Y(0.872)EGR 73.665 0.039675999999999996 3469000.0 8839.9 6514.9 10387.0 14519.0 14234.0 11288.0 8819.2 10952.0 9302.3 11683.0 True False 11650.804318657552 8620.714019186747 10249.261593254769 11171.868866313902 12257.85479672458 10582.159575559353 9604.091714945782 9259.620051923206 9794.00058697816 11273.981726028438 1.0334240911318082 0.7646556672416769 0.9091075222866576 0.9909426090802697 1.087269351202216 0.9386355089726762 0.8518810787827203 0.8213265088540422 0.8687259590253353 1.0 13.460709513681968 -10.423735385697823 7.412821690865699 1.0000000005940481 0.9165212687103667 0.06371145446678217 0.09353697970371405 9.699682160450398e-10 1.9484948584511775e-10 0.09693100787537645 0.023509222580456138 3.769333933972586e-11 10.423735385697823 -0.08347873188368149 AGTVS(ph)PGKEDPVSSR ddPTM_PC-9_AZD4547_30min_R2 1 AGTVSPGKEDPVSSR 15 1 Q7Z2K8;Q7Z2K8-2 Q7Z2K8 GPRIN1 G protein-regulated inducer of neurite outgrowth 1 1 AGT(0.059)VS(0.928)PGKEDPVS(0.012)S(0.001)R 107.73 0.006671600000000001 0.0 8752.7 10511.0 12532.0 12672.0 11703.0 12588.0 12047.0 13954.0 10551.0 10685.0 True False 11535.876532530237 13908.475196192103 12365.817491736661 9750.666180448361 10078.240458484466 11800.870370051482 13119.159661868629 11797.729931020482 11108.70431970658 10310.921402260878 1.118801713491945 1.3489071105849366 1.1992931581289337 0.9456639033549737 0.977433545005455 1.1445020197190041 1.2723557042139793 1.144197445674796 1.0773726116533846 1.0 13.331885639808938 -2.7508357890463713 0.015275651123791485 2.184776976590589e-07 2.4346189366470132 0.12215197435955327 0.11472751161917782 11437.013011325256 16.73971361473705 1109.4493775634603 1597.9198533928943 0.0017748604459729696 2.7508357890463713 2.4346187181693155 AGVAPLQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGVAPLQVK 9 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 117.93 0.00071212 0.0 19370.0 23649.0 30625.0 32091.0 38880.0 30635.0 26617.0 22301.0 28767.0 22943.0 False True 22648.958425061297 25996.716429203847 31355.216145959275 30293.045310425747 31261.743102415323 29028.446670164707 24095.645069607817 21715.62237986265 29187.662953182826 27102.384283311938 0.8356813994039336 0.9592040374547823 1.1569172593152988 1.1177262116041367 1.1534683729528725 1.0710661603318319 0.8890599741235499 0.8012439847675638 1.0769407830718007 1.0 14.726132155202432 -7.2552560361511125 24.444002095255005 0.9252481835445591 1.0577048325275888 0.17000786095798182 0.1127283350537212 585.8196528755622 2315869.6908197817 0.046461672715515934 0.03502660201075764 5.555766232682415e-08 7.2552560361511125 0.13245664898302978 AGVAPLQVK ddPTM_PC-9_Lapatinib_30min_R1 2 AGVAPLQVK 9 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 179.16 0.0052379 15252500.0 147938.0 134068.0 156981.0 154001.0 145824.0 134185.0 151203.0 139340.0 136720.0 125676.0 False True 145828.37699149363 133757.57378311342 144074.62814418372 165326.74727227623 137246.91902101462 128446.22035051278 159031.5514980391 145814.24508567905 121321.15387457414 147398.92914725636 0.9893448876131677 0.9074528190736394 0.9774469121159519 1.1216278722561777 0.9311256181780021 0.8714189519124036 1.0789193138517401 0.9892490123860116 0.8230802935709955 1.0 17.16936651773306 AGVGKS(ph)ES(ph)T(ph)Y(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 AGVGKSESTYR 11 1 Q96A58-2 Q96A58-2 4 AGVGKS(1)ES(1)T(1)Y(1)R 63.419 0.032602 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AGVLAGHDNR ddPTM_PC-9_AZD4547_30min_R2 3 AGVLAGHDNR 10 0 Q9HAV0;P62879;B3KVK2;E7EP32;P62879-2;P62873-2;P62873 Q9HAV0 GNB4;GNB2;GNB1 Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0 ;; 131.12 0.00015988 25879100.0 62995.0 64316.0 77038.0 112991.0 96128.0 83942.0 75819.0 100868.0 68020.0 86060.0 False True 83026.09962260125 85104.88923207037 76016.42578426492 86942.67064354803 82782.2864900618 78693.09347019861 82566.74411913495 85281.16831605075 71615.39833441783 83047.0655946253 0.9997475410856009 1.024779004805418 0.9153415023153403 1.0469084009293985 0.9968116982500508 0.9475722339705587 0.9942162739640323 1.0269016455359266 0.8623471259537518 1.0 16.341641572097437 -8.239292657378432 24.997241215345557 0.9311735115522686 0.9927487994503047 0.21748839737174552 0.04764475843031742 1022.2145090341478 1153788.3193252443 0.030402616842018945 0.011470931691927259 5.7637792955601175e-09 8.239292657378432 0.061575287898036124 AGVLAGHDNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 AGVLAGHDNR 10 0 Q9HAV0;P62879;B3KVK2;E7EP32;P62879-2;P62873-2;P62873 Q9HAV0 GNB4;GNB2;GNB1 Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0 ;;;; 132.88 0.00011074 24399300.0 138730.0 137505.0 160189.0 156110.0 191821.0 147078.0 157898.0 142045.0 141536.0 124123.0 False True 162214.24895760202 151155.58766111356 164008.51328016576 147363.66281544892 154235.05204856992 139364.97076397872 142940.75835747586 138316.4692591178 143605.69624019455 146625.51734287242 1.1063166350388831 1.0308955112338865 1.1185536886914749 1.0050342224597264 1.0518977517937973 0.9504823804855503 0.9748695926045394 0.9433315003122917 0.9794045323255961 1.0 17.161776673000432 -6.3913143019673555 1.284904648351473 0.9657537026608735 1.077358208827859 0.6400235412378197 0.03455244919734986 0.258620398267137 0.8765034895610199 0.013369569537939609 0.016930824916569692 4.061492896847931e-07 6.3913143019673555 0.11160450616698558 AGVLAGHDNR ddPTM_PC-9_Lapatinib_30min_R1 3 AGVLAGHDNR 10 0 Q9HAV0;P62879;B3KVK2;E7EP32;P62879-2;P62873-2;P62873 Q9HAV0 GNB4;GNB2;GNB1 Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0 ;; 142.98 0.00010736 20680400.0 98707.0 93821.0 88098.0 74227.6 78523.7 76203.0 58481.1 56381.5 85988.0 60528.2 False True 97299.42007935289 93603.76323884488 80854.92250811422 79686.54532001485 73905.09034953397 72943.97532786914 61508.965207780086 59001.190320785216 76303.12594621765 70990.41872124316 1.3705993263882106 1.3185407964192626 1.1389554247539495 1.1224971870206686 1.0410572536518738 1.0275185953515358 0.8664403776699258 0.8311148375172172 1.0748369613910267 1.0 16.115336702813067 -5.437174208597328 0.6683642926425252 0.9347051575629244 1.4798294180927671 0.8111502240231993 0.0707257172316207 0.6582903076070039 0.3900376864811607 0.03730474605588816 0.24222719484418234 3.654481699399084e-06 5.437174208597328 0.5451242605298428 AGVLAHLEEER ddPTM_PC-9_AZD4547_30min_R2 2 AGVLAHLEEER 11 0 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580 P35579 MYH9;MYH10 Myosin-9;Myosin-10 0 ; 163.84 0.001336 21729000.0 86565.0 100192.0 99095.0 128770.0 121645.0 129062.0 76258.0 120736.0 98050.0 114679.0 False True 114090.86933614542 132577.10463865267 97780.93555247721 99084.06597666773 104756.69149554324 120991.73273749503 83044.81426867895 102079.02543727156 103232.72282695767 110664.1231155707 1.0309652859851972 1.1980134203042248 0.8835829788337174 0.8953585243990096 0.9466183668770581 1.0933239186392758 0.7504221958362434 0.9224220331160677 0.9328472491409692 1.0 16.75582805615481 -5.269396535388555 24.97197240974598 0.9243525267264672 1.114489356232103 0.4049176510353476 0.09030650433504564 493.4940247378342 1548736.406432901 0.023315593191937534 0.04995487462001583 5.377785361083019e-06 5.269396535388555 0.19013682950563582 AGVLAHLEEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AGVLAHLEEER 11 0 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580 P35579 MYH9;MYH10 Myosin-9;Myosin-10 0 ;;; 152.04 0.00015106 22388800.0 103662.0 118692.0 130571.0 129956.0 130351.0 108217.0 116451.0 113140.0 96538.0 88814.0 False True 121209.92918217364 130474.95735189898 133684.30783327526 122674.98664303675 104809.65728248304 102541.91001485933 105419.9182477703 110170.19488173901 97949.68561804721 104915.27514876262 1.155312503449153 1.2436221242988164 1.2742120500920397 1.1692766994042774 0.9989933032522688 0.9773782689838251 1.004810005962355 1.0500872701856356 0.9336074797417374 1.0 16.678865216956602 -6.180180531569915 3.46294129625292 0.9951966819611617 1.2258094859382511 0.8822808076145053 0.03905943228997049 0.07719444209775127 1.7850666948620508 0.012030377595608011 0.01576884627403085 6.604188618847657e-07 6.180180531569915 0.2306128039770894 AGVLAHLEEER ddPTM_PC-9_Lapatinib_30min_R1 4 AGVLAHLEEER 11 0 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580 P35579 MYH9;MYH10 Myosin-9;Myosin-10 0 ;;; 173.24 6.0445e-06 27406100.0 107484.8 127537.3 134796.0 124830.3 166945.0 140382.0 142639.7 140555.0 116815.2 134932.7 False True 105952.04704170178 127241.9952177183 123713.59320760703 134010.73668367372 157125.62332649835 134378.1891064252 150024.88572458766 147085.6984212542 103658.24205741052 158255.63740847868 0.6694993541887267 0.8040281995723787 0.7817326146068713 0.8467991338455408 0.9928595650652013 0.8491210253671873 0.9479907836543834 0.9294183817389494 0.6550050522993688 1.0 17.27189736692705 -4.921846273720054 0.9429668624611591 0.8913864836466703 0.6052814081034323 0.3307508619741739 0.09545633234655358 2.0831427377983993 1.7045550007987758 0.03280953072229913 0.5835428008861487 1.1971642139494658e-05 4.921846273720054 -0.28610507554323794 AGVLT(ph)PPDLGPHPPPPAPR ddPTM_PC-9_AZD4547_30min_R2 2 AGVLTPPDLGPHPPPPAPR 19 0 I3L2J0 I3L2J0 CIC 1 AGVLT(1)PPDLGPHPPPPAPR;AGVLT(1)PPDLGPHPPPPAPR 184.66 1.7061e-10 13429900.0 60211.0 51967.0 95710.0 115397.0 99098.0 90568.0 69482.0 94698.0 65233.0 78944.0 True False 79356.84553339863 68764.31647992726 94440.82286419699 88794.00451587755 85339.9532559936 84904.76864274073 75665.76339553055 80064.60004355574 68681.08320419096 76180.19458868337 1.04169917078667 0.9026534632945432 1.2397030930953574 1.1655785994680035 1.120238058156272 1.1145254892188659 0.9932471793235713 1.0509897024527868 0.9015608791106132 1.0 16.217128352561886 -7.539373890862922 1.7261700706597445 0.9712410018159395 1.0987729956275345 0.2647701252662402 0.0890629058701009 0.5677004278465114 3.300658445028553 0.06178968041694569 0.02992874801933774 2.888192322113352e-08 7.539373890862922 0.12753199381159497 AGVLT(ph)PPDLGPHPPPPAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGVLTPPDLGPHPPPPAPR 19 0 I3L2J0 I3L2J0 CIC 1 AGVLT(1)PPDLGPHPPPPAPR;AGVLT(1)PPDLGPHPPPPAPR 144.75 0.00042975 11031500.0 37760.0 42041.0 53704.0 50798.0 55893.0 53119.0 44792.0 43377.0 47107.0 39120.0 True False 44152.02220600489 46214.55264071036 54984.50703355416 47951.95274933804 44941.167881257694 50333.34612934483 40548.977494002786 42238.39971173053 47795.85075731165 46212.14632625041 0.9554202891659398 1.000052071038704 1.1898280301757092 1.0376482496788804 0.97249687482551 1.0891800128476916 0.8774528066221692 0.9140107757284014 1.0342703067691454 1.0 15.495984476678395 -7.251832516208289 24.95418823449377 0.9492677015645544 1.042450081365703 0.23650121052660067 0.07375084865766673 942.2562080522578 2447549.9060625406 0.02943417433720544 0.02249187778013528 5.599735112268083e-08 7.251832516208289 0.09318237980114852 AGVLT(ph)PPDLGPHPPPPAPR ddPTM_PC-9_Lapatinib_30min_R1 2 AGVLTPPDLGPHPPPPAPR 19 0 I3L2J0 I3L2J0 CIC 1 AGVLT(1)PPDLGPHPPPPAPR;AGVLT(1)PPDLGPHPPPPAPR 134.58 8.635899999999999e-05 11298500.0 51260.0 39259.0 63125.0 56419.0 50612.0 53259.0 48794.0 43132.0 70593.0 43445.0 True False 50529.023000067275 39168.09819756576 57935.10616954663 60568.24146826673 47635.10166702049 50981.23672279283 51320.31456912439 45136.07018110739 62642.072962754624 50954.41036317631 0.9916516085638692 0.7686890677057414 1.1369988536147426 1.1886751517006688 0.9348572837464407 1.0005264776773064 1.0071810114834048 0.8858128248251949 1.2293748964275082 1.0 15.63691940393285 -5.264931017799165 24.991281892025548 1.0416904358159527 0.8801703413468732 0.25433219944045404 0.11450084766232817 393.52300301469484 2816649.1511614276 0.029608175310248383 0.06590115080872727 5.43336626809031e-06 5.264931017799165 -0.16152009446907944 AGVNS(ph)DSPNNCSGK ddPTM_PC-9_Lapatinib_30min_R1 1 AGVNSDSPNNCSGK 14 0 Q9Y4C1;F8WE62 Q9Y4C1 KDM3A Lysine-specific demethylase 3A 1 AGVNS(0.977)DS(0.023)PNNCSGK 146.96 5.2502e-08 0.0 8440.1 9510.7 8722.4 7700.8 7490.9 7075.0 8529.3 6481.2 9793.0 4263.9 True False 8319.742626275221 9488.67855848566 8005.2779414376755 8267.142521115726 7050.299989676038 6772.4187426305325 8970.90541981458 6782.340212783859 8690.009215138272 5000.909433710383 1.6636459301168462 1.897390601502178 1.6007644304604465 1.6531278221893309 1.409803573356282 1.3542374306918397 1.7938548055565748 1.3562213638713625 1.7376857810221913 1.0 12.287974762788954 -12.503305627755903 0.17671419881386805 1.1419862992624052e-23 1.753631650757703 0.5165779873603995 0.17581469552877263 49.253581552182794 0.9012509783751185 19.859280354664797 0.6311353973170422 3.1382993888713827e-13 12.503305627755903 1.753631650757703 AGVNSDS(ph)PNNCSGK ddPTM_PC-9_AZD4547_30min_R2 4 AGVNSDSPNNCSGK 14 0 Q9Y4C1;F8WE62 Q9Y4C1 KDM3A Lysine-specific demethylase 3A 1 AGVNS(0.351)DS(0.647)PNNCS(0.002)GK;AGVNS(0.005)DS(0.995)PNNCSGK;AGVNS(0.001)DS(0.999)PNNCSGK;AGVNSDS(1)PNNCSGK 181.51 6.952600000000001e-27 0.0 28302.6 24930.1 33744.399999999994 48760.0 43864.100000000006 36478.5 29737.300000000003 39973.7 28173.6 37825.100000000006 True False 37302.23806934888 32988.26729032336 33296.92720780073 37519.13533449036 37774.32686447992 34197.49362837009 32383.862091216564 33796.683169244214 29662.798978455652 36500.85476206439 1.0219551928991366 0.9037669803998211 0.9122232184657351 1.0278974445684566 1.0348888296100687 0.9368956933006347 0.8872083216219188 0.9259148419825324 0.8126603930734362 1.0 15.155642628379159 -6.9980888675797095 24.959564173105566 0.901954959786461 0.9758933629320429 0.2502877469114604 0.059950457025683156 88.85977697823218 1160495.026719033 0.021548142044437404 0.01887681040797652 1.004410241638191e-07 6.9980888675797095 0.07393840314558187 AGVNSDS(ph)PNNCSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AGVNSDSPNNCSGK 14 0 Q9Y4C1;F8WE62 Q9Y4C1 KDM3A Lysine-specific demethylase 3A 1 AGVNS(0.082)DS(0.918)PNNCSGK 140.27 1.818e-05 0.0 8630.9 8969.7 9565.4 7456.7 10038.0 12511.0 10052.0 7990.5 6923.1 6776.2 True False 10091.940901954647 9860.152537317845 9793.47541298151 7038.925273947581 8071.125958385931 11854.901135643231 9099.801789822202 7780.757841634571 7024.337240281575 8004.671419630313 1.2607564224567176 1.2317997854524334 1.223470008895607 0.8793521813632004 1.0083019695964843 1.4809978466537401 1.136811408336667 0.9720271368732731 0.8775297413277191 1.0 12.966626468040833 -7.76318617901348 4.392001591837592 0.9375173535031407 1.1742517897831428 0.3185393697911507 0.15163999787468072 0.2619005708682261 12.063194599852947 0.08903538597085787 0.04438211604028993 1.7250981958930202e-08 7.76318617901348 0.23673443628000213 AGVNSDS(ph)PNNCSGK ddPTM_PC-9_Lapatinib_30min_R1 1 AGVNSDSPNNCSGK 14 0 Q9Y4C1;F8WE62 Q9Y4C1 KDM3A Lysine-specific demethylase 3A 1 AGVNS(0.002)DS(0.992)PNNCS(0.006)GK 193.54 1.6212e-07 2251500.0 12491.0 12169.0 12436.0 9294.2 12011.0 11220.0 9634.0 9189.0 14420.0 6119.4 True False 12312.876049431141 12140.823428161131 11413.56008434822 9977.726472542312 11304.53659453456 10740.146755097461 10132.801380475967 9615.954486093755 12795.86775066821 7177.130136412044 1.715570961569123 1.6915986191425691 1.5902679577235634 1.3902111683779959 1.5750775560251817 1.4964402973005897 1.411817981266466 1.3398049503531668 1.782866899089705 1.0 12.809191364693904 -12.77765730236665 0.18404589187067302 1.8994384876971393e-23 1.6619995330381616 0.5626269968022465 0.14375329822206195 50.34468572455505 0.8701047907685214 20.499448275335578 0.4561404500721068 1.668563340627972e-13 12.77765730236665 1.6619995330381616 AGVNTVTTLVENK ddPTM_PC-9_Lapatinib_30min_R1 1 AGVNTVTTLVENK 13 0 P62424;Q5T8U3;Q5T8U2 P62424 RPL7A 60S ribosomal protein L7a 0 160.69 0.0013472000000000002 6426300.0 18603.0 14485.0 15173.0 12554.0 12992.0 13219.0 14225.0 15069.0 9345.9 14667.0 False True 18337.71780862761 14451.460872455742 13925.53450947375 13477.26303891633 12227.83610325477 12653.654184994053 14961.500896540447 15769.1607520891 8293.266325309993 17202.17140745096 1.066011805967984 0.8400951560217699 0.8095219016037729 0.7834628966130858 0.7108309650930694 0.7355847052839645 0.8697449026731598 0.916695943702714 0.4821057835592687 1.0 14.070303065467286 -4.506521866788905 1.655800579741246 0.7820724498102414 1.3715758908894926 0.28604980172924066 0.1308431366683768 2.750840680663934 4.156720195664527 0.034324642901061894 3.2312577150610724 3.115144044079552e-05 4.506521866788905 0.5895034410792512 AGVRPSS(ph)SGSAWEACSEAPSK ddPTM_PC-9_AZD4547_30min_R2 1 AGVRPSSSGSAWEACSEAPSK 21 1 Q12789;Q12789-3 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 1 AGVRPS(0.303)S(0.642)S(0.053)GS(0.002)AWEACSEAPSK 85.15700000000001 0.00021764 9802300.0 50370.0 63914.0 75763.0 99536.0 83195.0 85869.0 76921.0 100280.0 79106.0 84840.0 True False 66386.61223891463 84572.95059360878 74758.33311733518 76589.51301587016 71644.81030023194 80499.59785557292 83766.81998427786 84784.03020515526 83287.38166190013 81869.7774232861 0.8108805755716197 1.0330179616385988 0.9131371242261589 0.9355041069659232 0.8751069387890398 0.9832639148311223 1.0231714635204587 1.0355961976884558 1.0173153547405496 1.0 16.32104335267968 -6.965110028062981 5.3749522306823305 1.019882297455277 0.9214388898982189 0.47198233900051934 0.05271583712952656 0.17019886393288686 12.713152128724042 0.01834326170564425 0.01582871258562235 1.0836523370290773e-07 6.965110028062981 -0.09844340755705816 AGVVNGTGAPGQS(ph)PGAGR ddPTM_PC-9_AZD4547_30min_R2 2 AGVVNGTGAPGQSPGAGR 18 0 H0Y4T7;E7ESY4;Q13330-3;Q13330;Q13330-2 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 AGVVNGT(0.049)GAPGQS(0.951)PGAGR;AGVVNGT(0.001)GAPGQS(0.999)PGAGR 105.5 0.00034098 17151500.0 26197.0 28517.0 33757.0 47901.0 41314.0 36072.0 29008.0 42193.0 33947.0 34338.0 True False 34527.10106854966 37734.56256967082 33309.36012356803 36858.16451307266 35578.26423154976 33816.412137630825 31589.655804057875 35673.04134868478 35741.369115825924 33135.83707167377 1.0419866863138705 1.1387840448409339 1.0052367185268 1.112335397875943 1.0737095355277413 1.0205389429120186 0.9533380954200293 1.0765697957629068 1.0786318461946898 1.0 15.01610474453189 -6.754633235149226 20.708171846049684 1.0260714787311385 1.0762508452812531 0.20556160473267693 0.047696060465653695 31.539727690524035 95959.68982175874 0.016009793976859216 0.01558603591735611 1.7594088202904018e-07 6.754633235149226 0.05017936655011468 AGVVNGTGAPGQS(ph)PGAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGVVNGTGAPGQSPGAGR 18 0 H0Y4T7;E7ESY4;Q13330-3;Q13330;Q13330-2 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 AGVVNGTGAPGQS(1)PGAGR;AGVVNGT(0.001)GAPGQS(0.999)PGAGR 141.64 0.00013537 10944100.0 19214.4 15741.6 20138.4 16657.0 25010.0 21560.0 21297.0 20097.5 18791.9 11918.0 True False 22467.01841830137 17304.322015389873 20618.57583130731 15723.762292722617 20109.470035787213 20429.355645789157 19279.593983072362 19569.961920061418 19066.695986717998 14078.639057163911 1.5958231706259303 1.2291189471602069 1.4645290462799068 1.1168524335966683 1.4283674689106058 1.4510888135450626 1.3694217107769338 1.3900464271156414 1.3542996527790032 1.0 13.781220258952434 -8.71280556801526 6.7096367003584145 1.000000014779344 1.3731309786605734 0.45534593346501573 0.12401297117670806 15.73506919847313 556.3112017565154 0.11300761900323893 0.02924925784120982 1.9372890867707596e-09 8.71280556801526 0.37313096388122946 AGVVNGTGAPGQS(ph)PGAGR ddPTM_PC-9_Lapatinib_30min_R1 2 AGVVNGTGAPGQSPGAGR 18 0 H0Y4T7;E7ESY4;Q13330-3;Q13330;Q13330-2 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 AGVVNGTGAPGQS(1)PGAGR;AGVVNGT(0.002)GAPGQS(0.998)PGAGR 179.07 1.2149e-08 15060200.0 43660.0 40938.0 40477.0 32468.0 29041.0 35022.0 34651.0 26765.0 37409.0 25967.0 True False 43037.400393736585 40843.210576223224 37149.137305738426 34855.80503007293 27332.865476802763 33524.19070026945 36445.05923135488 28008.59961043632 33195.60448576613 30455.36135114741 1.4131305124742888 1.341084418776218 1.2197897400530704 1.1444883095685132 0.897473031485571 1.1007648313129084 1.196671377861744 0.9196607220482409 1.0899757222718187 1.0 14.894408601568006 -5.524882070325399 1.5415220463386445 1.0413245819862598 1.40247064605565 0.7147925394679828 0.08528929417870554 0.24079096957664445 1.0815059934079416 0.02697188303674853 0.08477455986150492 2.986193389075649e-06 5.524882070325399 0.3611460640693902 AGWGS(ph)PCHLSGESVILLGPTVGTESK ddPTM_PC-9_AZD4547_30min_R2 2 AGWGSPCHLSGESVILLGPTVGTESK 26 0 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4;A8MXE8;Q7Z5J4-4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 AGWGS(0.833)PCHLS(0.061)GES(0.106)VILLGPTVGTESK;AGWGS(0.996)PCHLS(0.003)GES(0.001)VILLGPTVGTESK 90.37799999999999 3.0254999999999997e-07 45081000.0 16335.5 18378.6 165594.0 519520.0 278670.0 220975.0 66472.0 323240.0 135286.0 221911.0 True False 21529.849200492157 24319.123036888614 163398.11536280237 399752.69050398754 239981.48069433976 207157.3983176142 72387.87922667326 273290.68531625805 142436.94176815703 214141.96343445184 0.10054007563577035 0.11356542476240356 0.763036411650433 1.8667648511887796 1.1206653607049666 0.9673834824113042 0.338036870801509 1.2762126625401538 0.6651519369848148 1.0 17.70820800956527 -5.3448829219172325 4.112595018281566 1.0336916059322128 0.10107952774798827 0.4843602220430979 0.3748173748017444 0.18637855610622173 5.771492621787403 0.10445935581008056 0.23856193077859156 4.519777731369208e-06 5.3448829219172325 -0.9326120781842245 AGWGS(ph)PCHLSGESVILLGPTVGTESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AGWGSPCHLSGESVILLGPTVGTESK 26 0 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4;A8MXE8;Q7Z5J4-4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 AGWGS(0.994)PCHLS(0.006)GES(0.001)VILLGPTVGTESK;AGWGS(0.872)PCHLS(0.088)GES(0.04)VILLGPTVGTESK 103.64 6.709900000000001e-10 11267800.0 12194.4 14348.3 56709.0 42767.0 72817.0 64969.0 35576.0 31839.0 51508.0 30896.0 True False 14258.67106962144 15772.70439938879 58061.1576300801 40370.90364248473 58549.03157120815 61561.911268612035 32205.98373206475 31003.25998620902 52261.20705643765 36497.20022739858 0.3906784898781744 0.4321620371183476 1.590838674427782 1.1061370020426429 1.604206109137522 1.686757090545189 0.8824234059435497 0.8494695426783658 1.4319237292400575 1.0 15.155498175789448 -5.246463104104964 24.324939446523636 1.270866411048524 0.41141994775806484 0.5828119217359069 0.2902120449926026 407.97191306345024 662636.6783102374 0.07762426264483441 0.20341236471103052 5.6693973437416854e-06 5.246463104104964 -0.859446463290459 AGWGS(ph)PCHLSGESVILLGPTVGTESK ddPTM_PC-9_Lapatinib_30min_R1 2 AGWGSPCHLSGESVILLGPTVGTESK 26 0 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4;A8MXE8;Q7Z5J4-4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 AGWGS(0.998)PCHLS(0.002)GESVILLGPTVGTESK;AGWGS(0.925)PCHLS(0.073)GES(0.002)VILLGPTVGTESK 123.21 1.1686e-12 11000800.0 51407.0 32179.0 157866.0 43039.0 91141.0 133949.0 60271.0 76261.0 182696.0 48308.0 True False 50673.92675311077 32104.491502571866 144886.86686038278 46204.23163389514 85780.26557010037 128220.3135203698 63391.53747173212 79804.364464468 162118.85260583085 56657.97343363617 0.8943829735185542 0.5666367777904384 2.557219365251206 0.8154938984539297 1.5140016553993996 2.263058590871681 1.1188458328108577 1.4085283964126132 2.8613598895435546 1.0 15.789991379261739 -5.2255749070169655 24.80505164706318 1.6691234750664923 0.730509392431723 0.26057674961406496 0.647132001384435 728.2320178979376 503666.80504561024 0.15767135116206948 0.4171280999480814 5.9487414414805194e-06 5.2255749070169655 -0.9386140826347693 AGYIT(ph)PVPGGVGPMTVAMLMKNT(ph)IIAAK ddPTM_PC-9_AZD4547_30min_R2 1 AGYITPVPGGVGPMTVAMLMKNTIIAAK 28 1 B8ZZU9;B9A062;P13995-2;P13995 B8ZZU9 MTHFD2 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial;NAD-dependent methylenetetrahydrofolate dehydrogenase;Methenyltetrahydrofolate cyclohydrolase 2 AGY(0.083)IT(0.906)PVPGGVGPMT(0.011)VAMLMKNT(1)IIAAK 67.992 0.0028650999999999998 0.0 2310.6 4881.7 9861.9 13694.0 13852.0 14276.0 6010.0 11424.0 9996.4 12230.0 True False 3045.3227365343664 6459.614058153458 9731.124762349004 10537.059870190955 11928.888902924611 13383.31946320742 6544.878357087278 9658.68329740418 10524.789295944924 11801.831422522282 0.25803814912342826 0.547339970119054 0.824543616491454 0.8928326030892397 1.010765912158333 1.1340036121569292 0.5545646368577353 0.8184054619668454 0.8917928852855593 1.0 13.526723135676514 -4.985222810382416 1.7344705380533247 0.8932101493126366 0.1728021183019535 0.6763707118480649 0.14293667115980288 0.3834938572889518 1.5737798815798039 0.042789799279262596 0.4046707972254425 1.0346112336883169e-05 4.985222810382416 -0.7204080310106832 AGYSQGATQY(ph)TQAQQT(ph)RQVT(ph)AIK ddPTM_PC-9_Lapatinib_30min_R1 1 AGYSQGATQYTQAQQTRQVTAIK 23 1 Q96KR1 Q96KR1 ZFR Zinc finger RNA-binding protein 3 AGY(0.139)S(0.08)QGAT(0.23)QY(0.527)T(0.026)QAQQT(0.999)RQVT(1)AIK 58.272 0.025437 0.0 23607.0 21462.0 18929.0 21242.0 23123.0 20843.0 22839.0 23958.0 18885.0 22089.0 True False 23270.359851006408 21412.306057621343 17372.730688053034 22804.207541234722 21762.950601567125 19951.5934774061 24021.491667914754 25071.17614297903 16757.972432133785 25907.054218257614 0.8982248485282037 0.8265048537448668 0.670579161246741 0.8802315905589835 0.8400395667613189 0.7701220412525909 0.9272181802509203 0.9677355029160548 0.6468497842693305 1.0 14.661057361631748 -7.260399747024161 24.98981222128839 0.8827621564804184 0.8124755177462157 0.09644487257226297 0.10650117168494912 244.91966335276987 5887274.972924443 0.04154720326334528 0.030284106277966 5.4903528083728044e-08 7.260399747024161 -0.07028663873420271 AHAWPS(ph)PYKDYEVK ddPTM_PC-9_AZD4547_30min_R2 2 AHAWPSPYKDYEVK 14 1 Q8NFJ5 Q8NFJ5 GPRC5A Retinoic acid-induced protein 3 1 AHAWPS(0.892)PY(0.108)KDYEVK;AHAWPS(0.973)PY(0.022)KDY(0.005)EVK 82.85 0.0041323 41178000.0 276470.0 427430.0 425200.0 362200.0 389240.0 375990.0 447850.0 463500.0 374520.0 340950.0 True False 364381.7090667607 565588.3886507836 419561.5701792558 278700.3859342169 335200.7447714682 352479.2858623812 487707.78239959123 391876.7251704162 394316.3626022657 329013.44427710347 1.107497931786244 1.7190433962158418 1.2752110209389815 0.8470790199670029 1.018805616007453 1.0713218319598947 1.4823339011910752 1.1910659943742836 1.198481002709915 1.0 18.327787011575495 -5.521605416791258 24.99992828910518 1.1274261246732948 1.434234825409596 0.24950040432254794 0.20801665825862992 59.3812152157031 1165861.0288259946 0.0573757159122042 0.10113775770837358 3.0088087486750855e-06 5.521605416791258 0.3068087007363012 AHAWPS(ph)PYKDYEVK ddPTM_PC-9_Lapatinib_30min_R1 3 AHAWPSPYKDYEVK 14 1 Q8NFJ5 Q8NFJ5 GPRC5A Retinoic acid-induced protein 3 1 AHAWPS(0.889)PY(0.11)KDYEVK;AHAWPS(0.963)PY(0.031)KDY(0.007)EVK;AHAWPS(0.488)PY(0.488)KDY(0.025)EVK 66.023 0.015837 60088000.0 393174.0 446546.0 295869.0 260555.0 314833.0 263273.0 228872.0 210762.0 319488.0 168044.0 True False 387567.26666071924 445512.0501727053 271543.79290736764 279717.08388599986 296315.14192549296 252013.4275093382 240721.87228070354 220554.77194450918 283503.89708221145 197090.1814954448 1.9664463430902914 2.2604477137944192 1.3777641831114942 1.4192339860038374 1.5034495360304971 1.2786706349203032 1.2213793221671327 1.1190550958501537 1.4384475925238511 1.0 17.588496381408476 -5.305828700672891 6.2890375405845855 1.304859113091028 2.1132951615955373 0.8090379635290298 0.15910484329826066 0.07518253249519916 7.9691391771768165 0.0417826115652331 0.09019146773599628 4.945056970388621e-06 5.305828700672891 0.8084360485045092 AHCGDPVSLAAAGDGS(ph)PDIGPTGELSGSLK ddPTM_PC-9_AZD4547_30min_R2 2 AHCGDPVSLAAAGDGSPDIGPTGELSGSLK 30 0 Q5JSP0-2;Q5JSP0-3;Q5JSP0 Q5JSP0-2 FGD3 FYVE, RhoGEF and PH domain-containing protein 3 1 AHCGDPVSLAAAGDGS(0.992)PDIGPT(0.007)GELSGSLK;AHCGDPVSLAAAGDGS(1)PDIGPTGELSGSLK 117.83 9.2695e-09 4523900.0 11580.099999999999 12856.9 19111.6 27316.1 22156.6 23035.4 16522.4 24085.6 20681.4 19784.8 True False 15262.330918956808 17012.641494617277 18858.1676967024 21018.79517453799 19080.538540755093 21594.992796495382 17992.86159187002 20363.72395202716 21774.576582085087 19092.140174024436 0.799403879284407 0.8910809023790641 0.9877450890686229 1.1009135163974355 0.9993923345856675 1.1310933504393692 0.9424224538404539 1.0666024744430047 1.1404995136014244 1.0 14.22069121332266 -5.158262323996884 1.770165544647972 1.053834131167666 0.791536403715993 0.6684771010805373 0.05949317339748573 0.2723261399947776 1.3813152414827543 0.016449674674588723 0.09313762991800391 6.9460463345196156e-06 5.158262323996884 -0.262297727451673 AHCGDPVSLAAAGDGS(ph)PDIGPTGELSGSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AHCGDPVSLAAAGDGSPDIGPTGELSGSLK 30 0 Q5JSP0-2;Q5JSP0-3;Q5JSP0 Q5JSP0-2 FGD3 FYVE, RhoGEF and PH domain-containing protein 3 1 AHCGDPVSLAAAGDGS(1)PDIGPTGELSGSLK 125.73 2.6394e-12 0.0 7850.1 11985.0 9294.3 15243.0 16282.0 11143.0 11312.0 9146.1 10410.0 9921.3 True False 9178.966883457599 13174.791593894366 9515.91136082904 14388.984128472775 13091.658981314966 10558.641463869604 10240.445468212178 8906.024566093985 10562.226556214879 11719.953153032417 0.7831914311946405 1.1241334689538007 0.8119410748981447 1.2277339286761377 1.1170402142714737 0.9009115758400165 0.8737616383357786 0.7599027444738244 0.9012174723140435 1.0 13.516679182584108 -6.927730249360431 7.471175578538416 0.866978673607545 1.0195389397700878 0.1655833031221703 0.1389802137232047 0.36821440682104994 32.318530501015374 0.04843424224156489 0.04267503747487866 1.181053988619845e-07 6.927730249360431 0.1525602661625428 AHCGDPVSLAAAGDGS(ph)PDIGPTGELSGSLK ddPTM_PC-9_Lapatinib_30min_R1 1 AHCGDPVSLAAAGDGSPDIGPTGELSGSLK 30 0 Q5JSP0-2;Q5JSP0-3;Q5JSP0 Q5JSP0-2 FGD3 FYVE, RhoGEF and PH domain-containing protein 3 1 AHCGDPVSLAAAGDGS(1)PDIGPTGELSGSLK 110.27 5.885000000000001e-07 0.0 5087.5 7020.8 8001.5 5195.9 7342.1 7179.7 6331.4 6995.6 7073.6 5566.9 True False 5014.951317066761 7004.5437689566625 7343.647556683209 5578.023819014287 6910.252113123987 6872.640967698149 6659.208912221873 7320.641114693378 6276.896679689787 6529.131247572015 0.7680886058052008 1.0728140549420628 1.1247511006022566 0.8543286399838546 1.0583723700903853 1.0526118570910754 1.0199226604149259 1.1212274400848814 0.9613678208757058 1.0 12.67267532724549 AHEAQDAGYR ddPTM_PC-9_AZD4547_30min_R2 1 AHEAQDAGYR 10 0 Q08209-3;Q08209;Q08209-2;Q08209-5;E5RJH4;E7ETC2;Q5F2F8;H0YC26;H0YB04;G3V111;P48454-2;P48454;P16298-2;P16298-3;P48454-3;P16298;P16298-4 Q08209-3 PPP3CA;PPP3CC;PPP3CB Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform;Serine/threonine-protein phosphatase;Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform;Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform 0 143.4 0.00010804 2749300.0 4291.3 2188.5 6338.9 7653.0 8673.9 6891.2 4456.9 6750.3 5246.5 6353.2 False True 5655.844135415011 2895.8898265499406 6254.84204423632 5888.719087671347 7469.678707412486 6460.2921746185875 4853.555465840644 5707.1962414624895 5523.819279057964 6130.776401763576 0.9225330960998762 0.47235286964908885 1.020236530309123 0.9605176737447806 1.2183903339328706 1.0537478047250626 0.7916706054463953 0.9309092140141924 0.9009983266505992 1.0 12.581854073104344 -5.289142666633008 24.88072139707811 0.9851659907014793 0.697442920841514 0.3858258762390171 0.14489796564944396 603.3545693002085 541880.5107905809 0.03834784568872308 0.07985621106313853 5.138748149158157e-06 5.289142666633008 -0.2877230698599652 AHEAQDAGYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AHEAQDAGYR 10 0 Q08209-3;Q08209;Q08209-2;Q08209-5;E5RJH4;E7ETC2;Q5F2F8;H0YC26;H0YB04;G3V111;P48454-2;P48454;P16298-2;P16298-3;P48454-3;P16298;P16298-4 Q08209-3 PPP3CA;PPP3CC;PPP3CB Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform;Serine/threonine-protein phosphatase;Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform;Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform 0 103.26 0.0024346999999999997 1994500.0 2964.5 3431.1 3896.4 4086.3 6566.0 4292.0 3913.9 4672.7 3209.8 2629.6 False True 3466.331298456075 3771.7169326500593 3989.304953179286 3857.357858963349 5279.439434425386 4066.9199643658203 3543.1470578178596 4550.046576134892 3256.7372526549952 3106.325664097852 1.1158943630795313 1.2142052509956172 1.284252002063625 1.2417750989684508 1.699576929567897 1.309238117358486 1.140623180231449 1.4647680469318498 1.0484210623166668 1.0 11.600993373031745 -8.388376493248765 6.2004646288917 1.0039299832854423 1.3095344398235298 0.336492125404246 0.16030955411872072 0.27714678813509175 12.108903795829946 0.15917324823644438 0.04127264415863511 4.089060222367091e-09 8.388376493248765 0.30560445653808754 AHEVGAQGGPPVAQVEQDLPIS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 AHEVGAQGGPPVAQVEQDLPISR 23 0 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 AHEVGAQGGPPVAQVEQDLPIS(1)R 146.5 6.8461e-17 0.0 4122.9 2879.1 6249.0 4270.1 5888.4 7514.2 3739.4 7097.0 6444.0 5534.8 True False 5433.896438352612 3809.712771130882 6166.134176975933 3285.6944173873544 5070.897301182596 7044.335886132893 4072.1993558223216 6000.321722835916 6784.616684313262 5341.028336662006 1.0173876818913576 0.7132919975316676 1.1544844528627973 0.615180113318931 0.9494234034249227 1.3189100379376393 0.7624373246383734 1.12343940990696 1.2702828475449466 1.0 12.382901823086724 -6.5327760887142015 24.809392377967818 1.087745525048269 0.8708382744853456 0.21716765761082624 0.19841105564773964 295.978899438664 741915.9767355506 0.06285704224335913 0.06292888353742959 2.9324047295244436e-07 6.5327760887142015 -0.21690725056292348 AHEVGAQGGPPVAQVEQDLPIS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 2 AHEVGAQGGPPVAQVEQDLPISR 23 0 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 AHEVGAQGGPPVAQVEQDLPIS(1)R;AHEVGAQGGPPVAQVEQDLPIS(1)R 152.15 2.4505e-17 0.0 12709.0 14740.8 14634.9 10527.2 14167.9 14729.5 11411.7 11434.2 12892.1 9473.099999999999 True False 12527.767329454833 14706.66858327206 13431.675014347691 11301.405405709727 13334.571977163125 14099.553621141544 12002.541988123065 11965.474674599322 11440.055938168498 11110.512712887692 1.1275597853304455 1.3236714599329866 1.2089158584704696 1.0171812676655874 1.2001761144376015 1.2690281704809805 1.0802869586927937 1.0769507207997622 1.0296604876657538 1.0 13.439637773348744 -7.439522766328302 5.447442831526934 1.0465660051288097 1.1902808026965983 0.45234793550973074 0.07862007632457219 0.23323819100621235 11.4834455463395 0.035834362917131046 0.02357526126317138 3.634772500573679e-08 7.439522766328302 0.1437147975677886 AHFNAMFQPS(ph)SPTR ddPTM_PC-9_AZD4547_30min_R2 3 AHFNAMFQPSSPTR 14 0 Q8WUA4;H0Y4Q6 Q8WUA4 GTF3C2 General transcription factor 3C polypeptide 2 1 AHFNAMFQPS(0.97)S(0.028)PT(0.003)R;AHFNAMFQPS(0.535)S(0.422)PT(0.044)R;AHFNAMFQPS(0.634)S(0.347)PT(0.018)R 139.49 7.1801e-05 97760900.0 173127.0 160536.0 202461.0 240902.0 223804.0 199613.0 197066.0 235013.0 185504.0 194332.0 True False 228177.7847346947 212426.12254741674 199776.2348543326 185365.76579879806 192732.67773824284 187131.16755458288 214604.4922325727 198697.14091148865 195309.3627260782 187528.4958300568 1.2167632642959785 1.1327671648362327 1.065311348923606 0.9884671925635309 1.0277514192451167 0.9978812378688623 1.1443833710853888 1.0595570557530263 1.041491650970595 1.0 17.516750310946996 -5.006631607746909 2.026146101981362 1.0414916058111858 1.2283708385225025 0.6458612561085189 0.04225757270337926 0.31113087916475973 1.9665816991800578 0.01227653196602999 0.09153860847061626 9.84846151735508e-06 5.006631607746909 0.18687923271131668 AHFNAMFQPS(ph)SPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AHFNAMFQPSSPTR 14 0 Q8WUA4;H0Y4Q6 Q8WUA4 GTF3C2 General transcription factor 3C polypeptide 2 1 AHFNAMFQPS(0.705)S(0.211)PT(0.084)R;AHFNAMFQPS(0.574)S(0.334)PT(0.092)R;AHFNAMFQPS(0.491)S(0.491)PT(0.018)R 92.8 0.0027765 117023000.0 126497.0 147914.0 151905.0 156500.0 154798.0 146054.0 158716.0 138745.0 131907.0 134695.0 True False 147910.4436703656 162597.92439042946 155526.9913029209 147731.8123798461 124466.4431267406 138394.67112662742 143681.2714756683 135103.09076247932 133835.89033147303 159114.1372549666 0.9295870638656826 1.021894893788604 0.9774555170651016 0.9284644025258338 0.7822462873132003 0.8697823682685214 0.9030075765387932 0.8490954549562642 0.8411313579070138 1.0 17.279702498927435 -5.999737843543744 5.387792855395075 0.8666180874208418 0.9777567752173943 0.3973789043165623 0.05615843432424091 0.1498019981402448 14.384545107092768 0.015637907135465638 0.022213422501395293 1.0006038197740166e-06 5.999737843543744 0.11113868779655256 AHFNAMFQPS(ph)SPTR ddPTM_PC-9_Lapatinib_30min_R1 4 AHFNAMFQPSSPTR 14 0 Q8WUA4;H0Y4Q6 Q8WUA4 GTF3C2 General transcription factor 3C polypeptide 2 1 AHFNAMFQPS(0.545)S(0.342)PT(0.114)R;AHFNAMFQPS(0.934)S(0.06)PT(0.007)R;AHFNAMFQPS(0.597)S(0.389)PT(0.014)R;AHFNAMFQPS(0.499)S(0.499)PT(0.002)R 79.48899999999999 0.0098446 41918500.0 173606.0 175210.0 199540.0 178093.0 204286.0 211123.0 189189.0 177715.0 189470.0 172454.0 True False 171130.346604559 174804.3120098704 183134.59144667463 191190.5533208325 192270.29912172895 202093.76144175068 198984.28071111333 185972.28768050365 168129.89339244837 202262.4441194895 0.8460806817080745 0.8642450296239979 0.9054305273720771 0.9452597794570498 0.9505981199759579 0.9991660207683482 0.9837925254851586 0.9194603006509593 0.8312462262797694 1.0 17.625868941083098 -5.4168355949016815 1.865164903282178 0.9481118679701453 0.8478058262408266 0.39228429750402916 0.045966688140641206 0.4168556280893566 2.716194646507586 0.014265660313235513 0.04568122006844264 3.829696916331292e-06 5.4168355949016815 -0.10030604172931878 AHFNAMFQPSS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 4 AHFNAMFQPSSPTR 14 0 Q8WUA4;H0Y4Q6 Q8WUA4 GTF3C2 General transcription factor 3C polypeptide 2 1 AHFNAMFQPS(0.155)S(0.773)PT(0.072)R;AHFNAMFQPS(0.481)S(0.484)PT(0.036)R;AHFNAMFQPS(0.183)S(0.716)PT(0.101)R;AHFNAMFQPS(0.224)S(0.756)PT(0.02)R 142.58 7.8388e-05 66810900.0 163212.0 156344.0 213998.0 241463.0 214505.0 211124.0 173631.0 216034.0 206009.0 197209.0 True False 215110.02097950675 206879.14052644477 211160.2466961907 185797.43591616172 184724.68337581898 197922.3829048893 189083.82263218297 182650.90926745604 216898.21516429124 190304.77293574772 1.1303448550506612 1.0870938092356361 1.1095898617712776 0.9763151656679268 0.9706781418361339 1.0400284756479203 0.9935842370912211 0.959781020989548 1.1397413308047835 1.0 17.5379522199919 -5.750704921317229 24.992810725809107 1.008519041924164 1.1068179775952647 0.45037999916208626 0.04929748368939831 189.2233370476365 440560.8377711929 0.013052178048446989 0.022323754553403807 1.7753953525053615e-06 5.750704921317229 0.0982989356711006 AHFNAMFQPSS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AHFNAMFQPSSPTR 14 0 Q8WUA4;H0Y4Q6 Q8WUA4 GTF3C2 General transcription factor 3C polypeptide 2 1 AHFNAMFQPS(0.237)S(0.757)PT(0.006)R 99.834 0.0018555999999999998 14022000.0 57040.0 70442.0 89036.0 83915.0 87810.0 68151.0 74701.0 68446.0 73235.0 54200.0 True False 66695.74540864713 77435.01622504031 91158.95591091028 79213.51460610087 70604.26084935918 64577.04158702114 67624.78049159468 66649.36502453174 74305.92332799204 64026.03095303606 1.0416973286626081 1.2094302125621361 1.4237795870522816 1.2372079516252543 1.1027430530739653 1.0086060407897102 1.0562076000181606 1.0409729297981931 1.1605580140130258 1.0 15.966370957967394 -6.345709170135712 3.88181809638291 1.0564822607819357 1.2410359425263457 0.4259634337616425 0.09540266169402001 0.23281566468643763 6.5819389951424085 0.032024388471989684 0.03707052530257905 4.511186997916491e-07 6.345709170135712 0.18455368174441 AHFNAMFQPSS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 3 AHFNAMFQPSSPTR 14 0 Q8WUA4;H0Y4Q6 Q8WUA4 GTF3C2 General transcription factor 3C polypeptide 2 1 AHFNAMFQPS(0.031)S(0.966)PT(0.004)R;AHFNAMFQPS(0.313)S(0.669)PT(0.018)R;AHFNAMFQPS(0.22)S(0.711)PT(0.068)R 147.49 0.00011630000000000001 40869000.0 82618.0 97807.0 125097.0 110042.0 128077.0 117258.0 107160.0 122590.0 111546.0 95194.0 True False 81439.85216971453 97580.53390074396 114812.00754838464 118134.85576935112 120543.76266907039 112243.14868174848 112708.22046209301 128285.97893679742 98982.5148485462 111648.15606196839 0.7294330246216761 0.8740004075533819 1.0283376958295685 1.0580994790794611 1.0796753562339592 1.0053291755167892 1.0094946879331912 1.1490201312916846 0.886557542370943 1.0 16.768599898797184 -4.986768974869694 2.1410224167195273 1.0352847153581541 0.7069293117538415 0.6901756543617561 0.06384442169607113 0.22605060462303342 1.6181591569162674 0.01636322264746926 0.1223878779752815 1.030934385325308e-05 4.986768974869694 -0.3283554036043126 AHGCFPEGRS(ph)PPGAAASAAAKPPPLSAK ddPTM_PC-9_AZD4547_30min_R2 1 AHGCFPEGRSPPGAAASAAAKPPPLSAK 28 2 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 AHGCFPEGRS(0.997)PPGAAAS(0.002)AAAKPPPLSAK 47.79600000000001 0.0096521 14406000.0 30928.0 13715.0 49071.0 75878.0 84998.0 44366.0 26680.0 35701.0 28273.0 47849.0 True False 40762.46065763649 18148.105538557204 48420.28647757816 58385.49940341391 73197.49487227733 41591.78700649064 29054.46831399143 30184.23077736581 29767.45305952653 46173.82107410209 0.8828045786424915 0.393038850075505 1.048652360823048 1.2644719030230116 1.5852596378109205 0.9007655428763851 0.6292411508972443 0.6537087482737162 0.6446824708692446 1.0 15.494787505840879 -7.005853742979346 24.921139496410024 0.7119008474855328 1.035743472175609 0.1854578053990361 0.298102208124883 467.6208147336136 1990807.847139133 0.12044161136631856 0.10288879701524598 9.86611690154572e-08 7.005853742979346 0.3238426246900761 AHGCFQDGR ddPTM_PC-9_AZD4547_30min_R2 2 AHGCFQDGR 9 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 0 ; 104.01 0.0022925000000000003 2607700.0 12176.9 10386.2 15001.400000000001 23168.0 18307.2 16567.6 12905.1 16802.4 16773.2 19943.8 False True 16048.900904745662 13743.336036789118 14802.47163425937 17826.975542031847 15765.561285274433 15531.62535294446 14053.628899508663 14205.975160740914 17659.797108833525 19245.573632420277 0.8339008860567484 0.7141037362293882 0.7691364215470176 0.9262896436612977 0.8191785595164821 0.8070232485448261 0.7302265532805172 0.7381424649671201 0.9176030523239161 1.0 14.23223905222143 -8.474719401457424 4.294580223069389 0.999134765742855 0.7932332613570764 0.5810367198027976 0.058555206676285075 0.13838289852378713 5.555532803047759 0.06051142623875546 0.015825840911449215 3.3518193093547323e-09 8.474719401457424 -0.2059015043857786 AHGCFQDGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AHGCFQDGR 9 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 0 ; 92.051 0.0061497 1459740.0 5697.4 9394.2 11740.1 9727.4 16497.0 14219.6 10888.900000000001 10549.2 14361.2 12369.5 False True 6661.857291220663 10326.794091895074 12020.028508577183 9182.405314656302 13264.531274705389 13473.899143824843 9857.424563190913 10272.294677801321 14571.205381278865 14611.992433091882 0.4559171051946008 0.7067341527297749 0.8226139291829456 0.6284156905160205 0.9077838861088589 0.9221123816975438 0.674611940043627 0.7030043797817458 0.9972086591202548 1.0 13.834865291253912 -4.387510794858951 1.0198421740628738 0.8268033000714804 5.153843889510632e-31 0.4684772802563032 0.12292687362464132 3.6509797646772797 1.7849646037154157 0.039458506238953146 3.992328317785848 4.097219256054785e-05 4.387510794858951 -0.8268033000714804 AHGCFQDGR ddPTM_PC-9_Lapatinib_30min_R1 3 AHGCFQDGR 9 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 0 ;; 113.71 0.00061111 2629700.0 14820.3 12756.4 14071.3 12898.5 14467.0 12952.599999999999 14725.500000000002 12434.199999999999 17761.7 11248.9 False True 14608.959804289829 12726.863339550873 12914.412030788768 13847.098718134643 13616.079503216344 12398.647491985334 15487.914337575146 13011.938325278812 15761.190307007198 13193.257376782934 1.107304995807798 0.9646490609625484 0.9788645564904336 1.049558749797629 1.0320483497257833 0.9397715164568888 1.1739264910294462 0.9862566880698317 1.1946397964420241 1.0 13.687513185317759 -7.254469971319362 24.98766807136213 1.0875604681744695 1.010986931406535 0.20021286550502915 0.07504238125855359 876.2594185484692 3141691.7574052154 0.027127185747768935 0.020576762047802896 5.56583117084006e-08 7.254469971319362 -0.07657353676793455 AHGCFQDGRS(ph)PGPPPPVGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AHGCFQDGRSPGPPPPVGVK 20 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 AHGCFQDGRS(1)PGPPPPVGVK 57.93600000000001 0.007627500000000001 6328100.0 34733.0 20912.0 28322.0 46011.0 64840.0 59085.0 49153.0 69890.0 48942.0 46738.0 True False 40612.61089198007 22988.00515740668 28997.303891783136 43433.15283967467 52135.06745783459 55986.478586802084 44496.872003096956 68055.46155457608 49657.68416083269 55211.229422195574 0.7355860631434031 0.41636466707921604 0.5252066326950124 0.7866724449757322 0.9442837626230376 1.01404151243723 0.8059388002906648 1.232638038797538 0.8994127586093872 1.0 15.752674106409364 -6.015279072369184 2.328281191914423 0.9900357990104431 0.5427840205602985 0.6934343357855968 0.125988201578471 0.15834968581410705 1.7179729583715613 0.03851831949148772 0.05860358632238025 9.654303058140184e-07 6.015279072369184 -0.44725177845014463 AHGCFQDGRS(ph)PGPPPPVGVK ddPTM_PC-9_Lapatinib_30min_R1 1 AHGCFQDGRSPGPPPPVGVK 20 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 AHGCFQDGRS(1)PGPPPPVGVK 46.663000000000004 0.031389 7888700.0 51482.0 31302.0 44665.0 41973.0 33692.0 37102.0 29791.0 27782.0 50290.0 26078.0 True False 50747.85723935745 31229.522142189137 40992.81611188596 45059.8344378234 31710.302801020596 35515.23394898628 31333.432211517513 29072.853143177363 44625.81062282277 30585.54755324921 1.6592103558390057 1.0210548654660758 1.3402675247359155 1.4732394232725299 1.0367740759197852 1.1611769868482662 1.0244522239455167 0.9505421831197151 1.4590489362706216 1.0 14.900562483491266 -6.270586360029511 24.844936729911367 1.101607726368172 1.345902780199561 0.3003856893554616 0.19863238100244532 827.207083538007 2246847.3700315366 0.05940547972958739 0.06829960671045622 5.363072154404221e-07 6.270586360029511 0.24429505383138905 AHGLSLIPSTGLCS(ph)PDLVNR ddPTM_PC-9_AZD4547_30min_R2 2 AHGLSLIPSTGLCSPDLVNR 20 0 O75030-11;O75030-10;O75030-9;O75030-12;O75030-4;O75030-3;O75030-8;O75030-7;O75030-6;O75030-2;O75030-5;O75030 O75030-11 MITF Microphthalmia-associated transcription factor 1 AHGLSLIPST(0.001)GLCS(0.998)PDLVNR;AHGLSLIPS(0.012)T(0.036)GLCS(0.953)PDLVNR 132.24 7.9609e-06 19573900.0 17922.9 15755.0 32672.0 57458.0 48885.0 37271.0 24560.0 48572.0 37029.0 34307.0 True False 23622.009380520998 20847.4956441829 32238.747932494436 44211.94581725079 42098.161566522496 34940.43847808933 26745.79242097564 41066.31347352205 38986.27734379825 33105.922372238085 0.7135282054648296 0.6297210332875415 0.9738060631571214 1.3354693858137592 1.2716202585500265 1.0554135325161529 0.8078854327104955 1.240452176857618 1.1776224478944377 1.0 15.014801705729125 -5.410576310747993 4.0124304426356625 1.1285206729944832 0.6753617461927154 0.6055384739873989 0.14476759480908288 0.1585619341215481 4.361270782763734 0.04175308950356019 0.09246305656149865 3.885292227129866e-06 5.410576310747993 -0.45315892680176784 AHGLSLIPSTGLCS(ph)PDLVNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AHGLSLIPSTGLCSPDLVNR 20 0 O75030-11;O75030-10;O75030-9;O75030-12;O75030-4;O75030-3;O75030-8;O75030-7;O75030-6;O75030-2;O75030-5;O75030 O75030-11 MITF Microphthalmia-associated transcription factor 1 AHGLSLIPS(0.004)T(0.03)GLCS(0.966)PDLVNR 128.8 1.6227e-05 4955200.0 6354.1 6283.1 9325.9 11248.0 17737.0 19766.0 14842.0 18750.0 15908.0 12042.0 True False 7429.723630804435 6906.844644438695 9548.264824672702 10617.811026508014 14261.562176119865 18729.43616394567 13436.058313225349 18257.832367267165 16140.62440502076 14225.119275580448 0.5222960515739696 0.48553861030151996 0.6712256424495316 0.7464127942136191 1.0025618695937388 1.316645280865768 0.9445304501797999 1.2834923921242245 1.134656525005633 1.0 13.79615312892257 -6.089528162462859 1.5014878780729566 1.1469509577991177 0.5221887326178348 0.837058019965078 0.11327254550524093 0.14200521038820116 0.6432613127213247 0.038859335944768106 0.06218425425888554 8.137140925837073e-07 6.089528162462859 -0.6247622251812829 AHGNSGMVR ddPTM_PC-9_AZD4547_30min_R2 1 AHGNSGMVR 9 0 C9K025;P18077 C9K025 RPL35A 60S ribosomal protein L35a 0 66.568 0.032632999999999995 764140.0 778.12 0.0 869.21 1134.6 767.33 1306.0 0.0 1259.9 3047.2 3110.6 False True 1025.5459740985552 0.0 857.683707468275 873.0354993952581 660.7994745799269 1224.335613543632 0.0 1065.2114046218076 3208.268771017904 3001.6988407929534 0.34165518544413287 0.0 0.28573276433078215 0.29084713214088787 0.2201418295532155 0.40788089627945534 0.0 0.3548695126058724 1.0688176733180805 1.0 11.5515635238827 -8.210688455069217 4.347958006280002 1.044802527513374 0.22297708169580033 0.8622545834262576 0.12803278466490237 0.06477451225463458 2.564292815290381 0.09582948614357294 0.0315987963615351 6.156183335237493e-09 8.210688455069217 -0.8218254458175738 down AHGS(ph)FSHVR ddPTM_PC-9_AZD4547_30min_R2 5 AHGSFSHVR 9 0 Q8N3D4 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 AHGS(0.927)FS(0.073)HVR;AHGS(0.978)FS(0.022)HVR;AHGS(0.976)FS(0.024)HVR;AHGS(0.984)FS(0.016)HVR;AHGS(0.804)FS(0.196)HVR 108.9 0.0013627000000000001 70140000.0 32489.5 31780.5 40608.2 53115.6 58716.1 42192.8 31709.300000000003 52652.4 46037.0 42870.0 True False 42820.48517641883 42052.92512345002 40069.70873507348 40870.619047839544 50564.38302866096 39554.47754603655 34531.366270946375 44516.18141178608 48470.42183360178 41369.134348612475 1.035082939265202 1.0165290085375083 0.9685894898696961 0.9879495834606543 1.2222731711657606 0.9561350066625992 0.8347132908306688 1.0760723450641687 1.1716566613443649 1.0 15.336267148966101 -7.979847549353456 24.998332306531474 1.0985072399045823 1.0045028400750124 0.1190460821600745 0.09812742727629674 449.79878955899153 557957.7398938066 0.05560486243189036 0.02670749359110952 1.0474961867213286e-08 7.979847549353456 -0.09400439982956987 AHGS(ph)FSHVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AHGSFSHVR 9 0 Q8N3D4 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 AHGS(0.975)FS(0.025)HVR;AHGS(0.956)FS(0.044)HVR;AHGS(0.996)FS(0.004)HVR 91.469 0.0059356 39686000.0 36610.1 36568.2 35228.2 34112.7 38748.0 34740.3 23608.1 42116.8 27481.300000000003 17878.2 True False 42807.46684756512 40198.449225185504 36068.173891692466 32201.476013865602 31155.607554845366 32918.457511197106 21371.769860157343 41011.27862643828 27883.16202298826 21119.37613624666 2.026928568883989 1.9033918883708834 1.7078238324374342 1.5247361383274485 1.475214388618884 1.558685128709838 1.011950813427557 1.9418792658392803 1.320264473870186 1.0 14.366279597842567 -1.5228787452803376 0.2137421545933139 1.205751782150966 5.46578658550884 0.5195787274783357 0.23827970716478158 45.22394945163487 0.5688095672550764 0.39083323069439796 65.84854601502288 0.029999999999999995 1.5228787452803376 4.260034803357874 AHGS(ph)FSHVR ddPTM_PC-9_Lapatinib_30min_R1 3 AHGSFSHVR 9 0 Q8N3D4 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 AHGS(0.941)FS(0.059)HVR;AHGS(0.992)FS(0.008)HVR;AHGS(0.964)FS(0.036)HVR 105.2 0.0015029000000000002 67154600.0 44061.9 32386.9 37986.8 31540.3 25046.1 21976.2 22893.2 21174.2 38223.4 28400.1 True False 43433.56922603715 32311.910122895217 34863.67193728844 33859.87887735643 23572.937640527176 21036.32915502432 24078.4978787121 22158.030632217484 33918.27818175393 33309.019444245445 1.3039582056367274 0.9700648851876518 1.046673619307385 1.0165378459739125 0.7077043405611179 0.6315505381428637 0.7228822187040383 0.6652261460084969 1.0182911039614448 1.0 15.023625263920572 -6.139118734904615 3.919373991567705 0.7632428696159649 1.0858239829640906 0.4872077130710336 0.14710893314809115 0.1964358663811529 5.2519619953988395 0.043953222400153466 0.058246802142269676 7.259074692182606e-07 6.139118734904615 0.32258111334812567 AHIAQLCEK ddPTM_PC-9_AZD4547_30min_R2 1 AHIAQLCEK 9 0 A0A087WVQ6;Q00610-2;Q00610;A0A087WX41;P53675-2;P53675 A0A087WVQ6 CLTC;CLTCL1 Clathrin heavy chain;Clathrin heavy chain 1;Clathrin heavy chain 2 0 72.643 0.026633999999999998 3331800.0 53029.0 51968.0 71246.0 85846.0 76406.0 73583.0 62017.0 75599.0 57105.0 66065.0 False True 69891.11892827875 68765.63971037109 70301.23148869062 66055.53100747868 65798.34576356188 68981.84337778013 67536.39285715167 63916.91164219706 60123.45371783188 63752.084458620986 1.0962954313069149 1.0786414325794196 1.1027283591695018 1.0361313134843892 1.0320971670544992 1.0820327517691375 1.0593597594598956 1.0025854399111147 0.9430821631699853 1.0 15.96018489311235 -7.84380131349639 3.0344476502196813 0.9713557195849178 1.069787870053167 0.7278414819037912 0.02507387439527082 0.13745959846787784 2.495888814373413 0.016780022261737707 0.007208847642930265 1.4328432645135577e-08 7.84380131349639 0.09843215046824905 AHIAQLCEK ddPTM_PC-9_Lapatinib_30min_R1 2 AHIAQLCEK 9 0 A0A087WVQ6;Q00610-2;Q00610;A0A087WX41;P53675-2;P53675 A0A087WVQ6 CLTC;CLTCL1 Clathrin heavy chain;Clathrin heavy chain 1;Clathrin heavy chain 2 0 ; 103.55 0.0023675999999999997 17097800.0 226230.0 225760.0 230221.0 231814.0 224120.0 210860.0 234660.0 212300.0 225570.0 205935.0 False True 223003.91871449852 225237.26659065357 211293.11805875972 248862.37486883462 210937.70223687319 201842.00933866738 246809.54659980207 222164.23303925432 200163.93124259592 241530.59035886123 0.9232947196591696 0.9325413656961655 0.8748089330830712 1.0303555110724483 0.8733374183512997 0.8356788638605762 1.0218562635610564 0.9198182007056217 0.8287311803660001 1.0 17.88184639544059 -8.016125917692458 24.883795601281673 0.9010019668890756 0.9272862757208071 0.0 0.06977839502376139 3471.2478173424456 5356426.9584137425 0.04340745581024888 0.017453060224664543 9.635496152051368e-09 8.016125917692458 0.026284308831731495 AHLDHIPDYTPPLLT(ph)TISPEQESDER ddPTM_PC-9_AZD4547_30min_R2 1 AHLDHIPDYTPPLLTTISPEQESDER 26 0 F5H0Q6;A0A0A0MQS2;Q8N2M8-3;Q8N2M8;K7EM61 F5H0Q6 CLASRP CLK4-associating serine/arginine rich protein 1 AHLDHIPDYTPPLLT(0.951)T(0.047)IS(0.002)PEQESDER 114.39 2.6079000000000003e-11 3348800.0 10133.0 9827.1 11071.0 18085.0 13732.0 13739.0 11305.0 13803.0 11671.0 12582.0 True False 13355.083220506676 13003.51789558553 10924.1913063371 13915.782660464683 11825.548831573831 12879.898158097965 12311.123099313092 11670.063511385673 12287.905233181267 12141.508009662737 1.0999525931933762 1.0709969375498305 0.8997392496585396 1.1461329720649116 0.9739769410984656 1.060815357354917 1.013969853622414 0.9611708448487727 1.0120575815954675 1.0 13.567659999079513 -7.522953862765028 24.559155951092748 0.9894825913589513 1.0383530625417363 0.1106903720358775 0.06462280056638012 5.098058875402349 1664380.804379594 0.028972028199469164 0.01696966156981362 2.999481151671027e-08 7.522953862765028 0.04887047118278498 AHLDHIPDYTPPLLTTIS(ph)PEQESDER ddPTM_PC-9_AZD4547_30min_R2 1 AHLDHIPDYTPPLLTTISPEQESDER 26 0 F5H0Q6;A0A0A0MQS2;Q8N2M8-3;Q8N2M8;K7EM61 F5H0Q6 CLASRP CLK4-associating serine/arginine rich protein 1 AHLDHIPDYTPPLLT(0.001)T(0.001)IS(0.793)PEQES(0.206)DER 119.64 5.4046e-12 7112300.0 9104.7 9100.1 13977.0 15609.0 16983.0 12433.0 9708.2 14838.0 9988.5 15802.0 True False 11999.805210475399 12041.529362845384 13791.655847590437 12010.586206646023 14625.203597918626 11655.562544554334 10572.210992724584 12545.128043319613 10516.4717180731 15248.77678975447 0.7869355933216866 0.7896718227875162 0.9044434211180098 0.7876426005996651 0.9591066745593116 0.7643604929928288 0.6933153484040744 0.8226973360741029 0.6896600208050151 1.0 13.896405898281794 AHLDHIPDYTPPLLTTIS(ph)PEQESDER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AHLDHIPDYTPPLLTTISPEQESDER 26 0 F5H0Q6;A0A0A0MQS2;Q8N2M8-3;Q8N2M8;K7EM61 F5H0Q6 CLASRP CLK4-associating serine/arginine rich protein 1 AHLDHIPDYTPPLLT(0.08)T(0.08)IS(0.822)PEQES(0.018)DER 115.34 9.768e-12 5189100.0 12467.0 11801.0 14480.0 12901.0 18496.0 15677.0 16839.0 13826.0 15132.0 11831.0 True False 14577.416865526033 12972.525289908011 14825.2581157058 12178.19879560633 14871.841574646947 14854.870522218765 15243.888016197381 13463.082149857904 15353.276873068531 13975.866645855527 1.043042069226447 0.9282090061838811 1.0607755848974243 0.871373425648542 1.064108720517673 1.062894409243945 1.0907293552860193 0.9633092881471013 1.0985563373003038 1.0 13.770650127155399 AHLGTALK ddPTM_PC-9_Lapatinib_30min_R1 2 AHLGTALK 8 0 D6RD47;P62266;D6RDJ2;D6RIX0;D6R9I7 D6RD47 RPS23 40S ribosomal protein S23 0 ; 145.34 0.0012074000000000002 15778100.0 328310.0 341460.0 314220.0 308390.0 344070.0 321090.0 320140.0 282680.0 311350.0 306560.0 False True 323628.239195319 340669.37034924066 288386.04452427616 331070.029358883 323832.4790676472 307357.72919734777 336715.28274294996 295814.34477407543 276282.4843391506 359548.4875344759 0.9000962329574181 0.9474921524084425 0.8020783135588181 0.9207938312552011 0.9006642783794104 0.8548436159611886 0.9364947828091293 0.8227383928174938 0.7684150925893097 1.0 18.455826815361533 -7.777329408200068 24.985089883321454 0.8466825651250416 0.8928177698863722 0.023806335455128003 0.06758344684948882 630.5921808584876 991513.3562390684 0.034756232909734945 0.01677877539224299 1.6698235886780025e-08 7.777329408200068 0.046135204761330595 AHLPLGQS(ph)NSCGSVLPPSLAAMAK ddPTM_PC-9_AZD4547_30min_R2 1 AHLPLGQSNSCGSVLPPSLAAMAK 24 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PRJ2;A0A1W2PRT1 E9PFQ4;A0A1W2PRT1 PHLDB2 Pleckstrin homology-like domain family B member 2 1 AHLPLGQS(0.467)NS(0.467)CGS(0.066)VLPPSLAAMAK 62.052 0.002048 45310000.0 63879.0 49149.0 104100.0 179040.0 134090.0 104100.0 82193.0 116470.0 105010.0 94800.0 True False 84191.19323425902 65035.453088920694 102719.5659822682 137765.09414042567 115473.91806188006 97590.61054356206 89508.01777106081 98472.23771434392 110560.6142178361 91481.08085487448 0.920312620352834 0.7109169730088004 1.1228503754259578 1.5059408224414852 1.2622710289690149 1.0667846251005684 0.9784320094890031 1.076421887390686 1.2085626140909875 1.0 16.481185790934752 -5.328461746981986 6.633387967238622 1.164050547224738 0.8167851502504453 0.4407985649008014 0.15166899483095875 0.20827342015996228 17.03731033012926 0.04341166651812928 0.09195687263482662 4.693947771775326e-06 5.328461746981986 -0.3472653969742927 AHLPLGQS(ph)NSCGSVLPPSLAAMAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AHLPLGQSNSCGSVLPPSLAAMAK 24 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PRJ2;A0A1W2PRT1 E9PFQ4;A0A1W2PRT1 PHLDB2 Pleckstrin homology-like domain family B member 2 1 AHLPLGQS(0.723)NS(0.245)CGS(0.031)VLPPSLAAMAK;AHLPLGQS(0.763)NS(0.16)CGS(0.077)VLPPSLAAMAK 87.23700000000001 1.278e-05 126066000.0 158269.0 151268.0 194918.0 218834.0 227287.0 195655.0 220208.0 198773.0 194908.0 146447.0 True False 185060.81574476164 166284.88734461518 199565.5843506318 206573.44044940022 182751.7439433817 185394.50736905765 199348.3040721416 193555.41936740215 197758.16077029068 172996.68182618567 1.0697362156963053 0.9612027559678052 1.1535804169419885 1.19408903262636 1.056388723842676 1.0716651060124287 1.1523244374850616 1.118838912539793 1.1431326814058984 1.0 17.400384840860568 -5.267424664036778 24.988550422060595 1.1165487199977437 1.0154694843432346 0.2953686966721859 0.05872208272783761 497.74642112798676 2078095.2040807453 0.014965003286633673 0.03244262904429375 5.402258182408419e-06 5.267424664036778 -0.10107923565450916 AHLPLGQS(ph)NSCGSVLPPSLAAMAK ddPTM_PC-9_Lapatinib_30min_R1 1 AHLPLGQSNSCGSVLPPSLAAMAK 24 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PRJ2;A0A1W2PRT1 E9PFQ4;A0A1W2PRT1 PHLDB2 Pleckstrin homology-like domain family B member 2 1 AHLPLGQS(0.601)NS(0.145)CGS(0.255)VLPPSLAAMAK 75.018 0.00016284 39863000.0 63985.0 55011.0 77340.0 65170.0 74508.0 66106.0 62377.0 60448.0 76479.0 52312.0 True False 63072.562166588075 54883.62540936576 70981.40374103335 69962.81920074685 70125.58592836405 63278.80048061259 65606.57584699497 63256.63475627327 67865.12966042687 61354.0594986415 1.0280096000491152 0.8945394299554211 1.156914543569933 1.1403127971067009 1.1429657059597949 1.0313710453342326 1.0693110836202717 1.0310097697394236 1.1061228908892253 1.0 15.904871182684612 -5.260691635579391 24.999997392252382 1.0874640680802479 0.961274516170093 0.41527633110615825 0.05853640097494837 60.70938697482055 2029655.6995341072 0.01529449823045108 0.03602696338827663 5.486663991697243e-06 5.260691635579391 -0.1261895519101549 AHLPLGQSNS(ph)CGSVLPPSLAAMAK ddPTM_PC-9_AZD4547_30min_R2 2 AHLPLGQSNSCGSVLPPSLAAMAK 24 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PRJ2;A0A1W2PRT1 E9PFQ4;A0A1W2PRT1 PHLDB2 Pleckstrin homology-like domain family B member 2 1 AHLPLGQS(0.244)NS(0.666)CGS(0.09)VLPPSLAAMAK;AHLPLGQS(0.019)NS(0.51)CGS(0.471)VLPPSLAAMAK 124.97 5.8798e-08 178920000.0 315622.0 300826.0 577558.0 860833.0 666739.0 645890.0 554121.0 689074.0 561244.0 568415.0 True False 415983.23065457033 398062.1215269415 569899.2035503074 662381.2515872713 574173.7986028765 605502.3961957867 603436.6955253857 582593.4466452651 590910.2120376653 548514.9638620606 0.7583808247010394 0.7257087732378534 1.0389856997477 1.2075901210123514 1.0467787324527185 1.1038940340523822 1.1001280462371064 1.0621286291685827 1.0772909600808378 1.0 19.065171453306142 -5.3058007317068006 4.676573958363528 1.0895015422456804 0.7392095740468685 0.8736895460744012 0.05145469850677827 0.05495274440934713 2.791102767196621 0.012999397838982131 0.029762822665725684 4.94537544688364e-06 5.3058007317068006 -0.3502919681988119 AHLPLGQSNS(ph)CGSVLPPSLAAMAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AHLPLGQSNSCGSVLPPSLAAMAK 24 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PRJ2;A0A1W2PRT1 E9PFQ4;A0A1W2PRT1 PHLDB2 Pleckstrin homology-like domain family B member 2 1 AHLPLGQS(0.077)NS(0.797)CGS(0.127)VLPPSLAAMAK 101.51 1.6791e-06 22354000.0 59662.0 80146.0 124770.0 105470.0 129120.0 105500.0 114340.0 126240.0 111410.0 80806.0 True False 69761.5982217865 88102.36521353852 127744.9899928602 99560.8578383538 103819.86289567567 99967.39427786431 103508.88745008664 122926.33376233625 113039.16048298756 95455.48814005591 0.7308285734124541 0.9229680443755249 1.3382676311437212 1.0430082101960898 1.0876259177821943 1.0472671213119602 1.084368111954071 1.2877869691680175 1.1842080815419667 1.0 16.542540526207752 -5.01466114570045 5.214490559144102 1.1352592242578057 0.7663883246193703 0.6079399720915096 0.10396509301153853 0.10170333929511943 8.76407579933109 0.026740997378637662 0.09023323693184825 9.668049254880098e-06 5.01466114570045 -0.36887089963843533 AHLPLGQSNS(ph)CGSVLPPSLAAMAK ddPTM_PC-9_Lapatinib_30min_R1 2 AHLPLGQSNSCGSVLPPSLAAMAK 24 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PRJ2;A0A1W2PRT1 E9PFQ4;A0A1W2PRT1 PHLDB2 Pleckstrin homology-like domain family B member 2 1 AHLPLGQS(0.331)NS(0.52)CGS(0.144)VLPPS(0.005)LAAMAK;AHLPLGQS(0.229)NS(0.679)CGS(0.092)VLPPSLAAMAK 85.712 1.196e-05 93417000.0 190284.0 162489.0 204583.0 162452.0 194149.0 161576.0 144114.0 145430.0 169508.0 140387.0 True False 187570.5152661883 162112.76670379454 187762.97545321798 174399.26200398526 182729.5375316203 154665.77113205224 151575.5177647825 152187.20871831724 150416.22404162737 164652.7058960811 1.1391887806846706 0.9845739602124144 1.1403576663460526 1.059194630630945 1.1097876377868225 0.93934545618502 0.9205771441159786 0.9242921814741912 0.9135363018969215 1.0 17.32906669575835 -6.769359021679162 24.80548154988533 0.9336326203700288 1.0824130181032838 0.7047751889810048 0.047477188128828306 84.28921586301983 264004.2919504944 0.015516317708706843 0.013929832985758726 1.70075195292488e-07 6.769359021679162 0.14878039773325502 AHLPLGQSNSCGS(ph)VLPPSLAAMAK ddPTM_PC-9_AZD4547_30min_R2 1 AHLPLGQSNSCGSVLPPSLAAMAK 24 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PRJ2;A0A1W2PRT1 E9PFQ4;A0A1W2PRT1 PHLDB2 Pleckstrin homology-like domain family B member 2 1 AHLPLGQS(0.033)NS(0.118)CGS(0.598)VLPPS(0.251)LAAMAK 69.726 0.00045998 89693000.0 45596.0 46658.0 86447.0 126420.0 131690.0 103210.0 81146.0 114450.0 78128.0 107370.0 True False 60094.57954428332 61739.286053080694 85300.65629653368 97275.82216952967 113407.11663486437 96756.26238425577 88367.83679936851 96764.38229936172 82257.68657852682 103611.00898088467 0.5800018756247248 0.5958757342520529 0.8232779232202141 0.9388560455721091 1.094546976719308 0.9338415225944422 0.8528807669045246 0.933919891825529 0.7939087495393723 1.0 16.66081777628667 -5.376622600959795 2.579205617635355 0.9350317445436439 0.5751806172834281 0.7683392733751595 0.07539792347035296 0.13883995758651924 1.761623573856918 0.02225245405026745 0.0603008934187813 4.2012391031572175e-06 5.376622600959795 -0.35985112726021584 AHLPLGQSNSCGS(ph)VLPPSLAAMAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AHLPLGQSNSCGSVLPPSLAAMAK 24 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PRJ2;A0A1W2PRT1 E9PFQ4;A0A1W2PRT1 PHLDB2 Pleckstrin homology-like domain family B member 2 1 AHLPLGQS(0.265)NS(0.265)CGS(0.471)VLPPSLAAMAK 73.796 0.00019369 12173000.0 36727.0 35615.0 38685.0 54507.0 47982.0 51913.0 36883.0 46502.0 52573.0 36601.0 True False 42944.155708684855 39150.62182866482 39607.397113679464 51453.14950407832 38580.27154166903 49190.5908923865 33389.17523020418 45281.37177294175 53341.78066665558 43236.4715666434 0.9932391370672332 0.9054999265682268 0.916064509395264 1.1900404366894273 0.8923085104713635 1.1377105741981188 0.7722456070158062 1.0472957235454887 1.2337218726194195 1.0 15.39996117225637 -8.001046380310814 24.99999802728079 1.124743588494399 0.974374695713575 0.17800686223635942 0.12518716242941672 55.82133742546735 1333655.856785052 0.0663784103557538 0.03123392438203052 9.975935205202824e-09 8.001046380310814 -0.150368892780824 AHLPLGQSNSCGS(ph)VLPPSLAAMAK ddPTM_PC-9_Lapatinib_30min_R1 1 AHLPLGQSNSCGSVLPPSLAAMAK 24 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PRJ2;A0A1W2PRT1 E9PFQ4;A0A1W2PRT1 PHLDB2 Pleckstrin homology-like domain family B member 2 1 AHLPLGQS(0.412)NS(0.076)CGS(0.511)VLPPS(0.001)LAAMAK 60.747 0.019283 0.0 13639.0 11686.0 14508.0 13322.0 13361.0 11070.0 10502.0 11540.0 14376.0 11116.0 True False 13444.50535891372 11658.941784985698 13315.208242499522 14301.744320889233 12575.132248736685 10596.561905430377 11045.74217331935 12076.190528841224 12756.823494008759 13037.385788861053 1.0312270862154362 0.8942699076180536 1.0213096749714836 1.0969794522080054 0.964544000798127 0.8127827217082063 0.8472359683301438 0.9262739267222528 0.9784801723753543 1.0 13.670366993938556 -6.5295906568384305 24.875875477568506 0.9025085975610818 1.0067788423957618 0.2997436155332637 0.06967791118833265 196.24430167091867 727319.4172666653 0.023952894450552615 0.024008184315984876 2.953992192764855e-07 6.5295906568384305 0.10427024483467995 AHLTVGQAAAGGS(ph)GNLLTER ddPTM_PC-9_Lapatinib_30min_R1 1 AHLTVGQAAAGGSGNLLTER 20 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 AHLTVGQAAAGGS(0.676)GNLLT(0.324)ER 62.468 0.0099542 7467600.0 20716.0 20051.0 33046.0 18857.0 26809.0 24662.0 15756.0 14169.0 28432.0 13745.0 True False 20420.58604115088 20004.573141429762 30329.08544124892 20243.806685107946 25232.147328521944 23607.263749929913 16571.768585299902 14827.34346647758 25229.688757766904 16120.804935938744 1.2667224820533909 1.2409165188043918 1.88136296926682 1.2557565683322445 1.56519152913208 1.4643973327474058 1.0279740156371353 0.9197644612287567 1.5650390199512536 1.0 13.976636161138309 -7.2523890595236775 24.288131255659355 1.1215080784175515 1.4530122846668774 0.29549641217510203 0.2399436335434651 550.2117115522233 1476592.957668111 0.09111133494475694 0.0694752635463992 5.5925637130192326e-08 7.2523890595236775 0.33150420624932586 AHLY(ph)S(ph)LRCAAEEK ddPTM_PC-9_AZD4547_30min_R2 1 AHLYSLRCAAEEK 13 1 Q08397 Q08397 LOXL1 Lysyl oxidase homolog 1 2 AHLY(1)S(1)LRCAAEEK 91.85799999999999 0.012703 0.0 4190.2 5734.1 7782.3 8700.4 8771.6 7428.9 3758.4 12660.0 7285.0 4804.4 True False 5522.596438425652 7587.535688562946 7679.101617135508 6694.657199840035 7553.814748837247 6964.369708617371 4092.8903190144492 10703.68789785863 7670.0702273777315 4636.19941834555 1.1911904428814275 1.636585272527081 1.656335486077049 1.443996816303699 1.6293118710439038 1.502172163056489 0.882811533692616 2.308720340092336 1.654387470268661 1.0 12.178726907449663 -11.436048473121392 2.676887877920695 0.6766575689573208 1.5522490498099486 0.18204196291044883 0.34630946901178405 115180351.59855738 72795979.3524475 234267772.0653994 0.08666691194519197 3.663966775548344e-12 11.436048473121392 0.8755914808526278 AHPPELK ddPTM_PC-9_Lapatinib_30min_R1 3 AHPPELK 7 0 C9JVQ0;P62308;A8MWD9 C9JVQ0 SNRPG;SNRPGP15 Small nuclear ribonucleoprotein G;Putative small nuclear ribonucleoprotein G-like protein 15 0 ;; 77.282 0.022055 0.0 152646.0 159313.0 167485.0 156829.0 161729.0 145005.0 174485.0 152346.0 148214.0 157349.0 False True 150469.2400481516 158944.1205366617 153715.0298107964 168362.72782620759 152216.41819144768 138803.47417316464 183518.979538338 159424.55132641646 131520.57855738822 184546.5649956368 0.8153456557249338 0.8612683771189108 0.8329335732389852 0.9123048582897663 0.8248130665290166 0.7521325264246794 0.9944318364455978 0.8638716810046597 0.7126687974956224 1.0 17.4936253590814 -11.07159257493295 3.256343553779087 1.0052191516040274 0.8456196187187216 0.29035971888008505 0.0742267726122887 79828984.65446751 99519410.0639808 3669631.2054609517 0.018993094376262436 8.480225972797961e-12 11.07159257493295 -0.15959953288530582 AHPS(ph)PGMDSR ddPTM_PC-9_Lapatinib_30min_R1 1 AHPSPGMDSR 10 0 A0A0X1KG68;Q5XG87-2;Q5XG87 A0A0X1KG68 PAPD7 Non-canonical poly(A) RNA polymerase PAPD7 1 AHPS(0.994)PGMDS(0.006)R 87.667 0.01048 1657300.0 9902.1 14753.0 12922.0 12451.0 11571.0 10790.0 10660.0 9066.4 10150.0 9400.2 True False 9760.894238177252 14718.840334921611 11859.603040362474 13366.688075318396 10890.416529461276 10328.536852718507 11211.92264021941 9487.658042520447 9006.800115761616 11025.012045020834 0.8853409137621315 1.3350407486918803 1.0756997808196103 1.2123966868004574 0.9877918033096077 0.9368277159736191 1.0169533234462986 0.8605576124341112 0.8169424286324756 1.0 13.428492611502978 -6.44634308124495 4.164056643084013 0.9256956366673086 1.1376579796005055 0.3855499544176896 0.11939437221238926 0.22483385311847767 7.308230207469323 0.037030938294799746 0.041392390992876366 3.5781366202081827e-07 6.44634308124495 0.21196234293319693 AHQGTGAGIS(ph)PVILNSGEGK ddPTM_PC-9_AZD4547_30min_R2 1 AHQGTGAGISPVILNSGEGK 20 0 Q8IZD4;Q8IZD4-2;F5GZK9 Q8IZD4 DCP1B mRNA-decapping enzyme 1B 1 AHQGT(0.001)GAGIS(0.997)PVILNS(0.002)GEGK 66.77199999999999 0.0033085000000000002 6219200.0 48110.0 76309.0 57019.0 84052.0 51402.0 57492.0 54687.0 90287.0 52854.0 70768.0 True False 63407.97924983489 100974.39194617292 56262.89080444724 64675.109990455 44265.719563105034 53897.01615149346 59554.03705724328 76335.21873885958 55647.75453642039 68290.43386010281 0.9285045600930002 1.4786022908131646 0.8238766050264853 0.9470595855774759 0.6481979548378051 0.7892322995326818 0.8720699765833003 1.1178025152869435 0.8148689558836054 1.0 16.05939587916042 -5.290673459438905 24.884661435328027 0.8719173305941977 1.2035535370140489 0.3657140889618552 0.17212335642621854 580.6475400685663 494258.35262635007 0.043926044504318286 0.09146092298110718 5.120667073517137e-06 5.290673459438905 0.33163620641985114 AHQGTGAGIS(ph)PVILNSGEGK ddPTM_PC-9_Lapatinib_30min_R1 2 AHQGTGAGISPVILNSGEGK 20 0 Q8IZD4;Q8IZD4-2;F5GZK9 Q8IZD4 DCP1B mRNA-decapping enzyme 1B 1 AHQGTGAGIS(1)PVILNSGEGK;AHQGTGAGIS(1)PVILNSGEGK 114.92 5.2155e-05 7379000.0 102517.0 226396.0 134133.0 124293.0 127178.0 125084.0 126327.0 106640.0 123431.0 103588.0 True False 101055.08878068472 225871.79397172868 123105.10250835329 133433.9218492929 119697.64008156814 119734.4489050455 132867.59393724165 111594.88370845997 109528.9009939479 121493.04777766629 0.831776719978387 1.859133490379439 1.013268699404406 1.0982844227718984 0.9852221363366918 0.9855251069523003 1.0936230209681703 0.9185289672926793 0.9015240213117962 1.0 16.89051423498679 -5.463533190971741 24.99999800920353 1.0016360950110597 1.3681421080783673 0.25254498079621335 0.237491840280837 286.24111577822447 120581.39341229327 0.05663786398325062 0.11790077268448594 3.4392742571006105e-06 5.463533190971741 0.3665060130673077 AHQS(ph)ESYLPIGCK ddPTM_PC-9_AZD4547_30min_R2 1 AHQSESYLPIGCK 13 0 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 AHQS(0.531)ES(0.468)YLPIGCK 64.58800000000001 0.023637000000000002 7636500.0 33171.0 46692.0 63767.0 99539.0 86405.0 76553.0 70405.0 78144.0 64661.0 66373.0 True False 43718.68800033825 61784.27588817445 62921.40791538234 76591.82141221972 74409.1572088653 71766.12880827385 76670.90860744247 66068.64037047916 68078.84845195226 64049.301472368905 0.6825786854084371 0.9646362172244518 0.9823902286042395 1.1958260223222217 1.1617481455432528 1.1204826150872857 1.1970608085479055 1.0315278832350951 1.0629132072786418 1.0 15.966895216036049 -4.580661238332645 1.2150242352248097 1.1134170697285821 0.32810547388728983 0.7665299515816035 0.06988620489529916 1.0412843036905353 0.9642852924492661 0.021399151477638434 1.1578587599430037 2.6262663047370508e-05 4.580661238332645 -0.7853115958412923 AHQS(ph)ESYLPIGCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AHQSESYLPIGCK 13 0 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 AHQS(0.74)ES(0.256)Y(0.005)LPIGCK 73.593 0.011858 6182200.0 52261.0 55286.0 69491.0 86334.0 90097.0 76833.0 74946.0 72709.0 71043.0 59686.0 True False 61107.75509819968 60774.42870755483 71147.92898608516 81496.98587860442 72443.13961672624 72803.74222323376 67846.57231794823 70800.46579155349 72081.86947484844 70506.59932588393 0.8666955388921473 0.8619679475201084 1.0090960231571655 1.1558774165510741 1.0274660855772033 1.0325805374151198 0.9622726520160054 1.0041679285127807 1.0223421660387215 1.0 16.10547067775796 -5.288731316000906 5.1585816173780366 1.0302552372279488 0.8628526034239933 0.6554850690680923 0.047186203512805835 0.10740838198199858 8.347077836177863 0.013405121974324278 0.03078153352805107 5.143617722179136e-06 5.288731316000906 -0.16740263380395548 AHQS(ph)ESYLPIGCK ddPTM_PC-9_Lapatinib_30min_R1 2 AHQSESYLPIGCK 13 0 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 AHQS(0.964)ES(0.034)Y(0.001)LPIGCK;AHQS(0.741)ES(0.259)YLPIGCK 84.759 0.008428100000000001 12722800.0 82955.0 91210.0 95274.0 72201.0 73764.0 85159.0 74529.0 80282.0 83990.0 52549.0 True False 81772.04648791613 90998.80884892563 87440.93948827544 77510.90239547536 69425.34654560385 81516.94808532475 78387.74694680229 84012.1948038502 74530.16174609048 61632.02463285882 1.3267785209885796 1.4764857943740186 1.4187581863351075 1.2576400476409273 1.1264492276404963 1.322639464968418 1.271867140723627 1.3631256689084899 1.2092765439731326 1.0 15.911392564454573 -14.52287874525907 0.10541697800362958 0.034951539290471005 1.4975564038286127 0.5729330012746593 0.08675853328232896 144.96249262288896 1.0232260373950786 30.607460486284197 1.3771565600800446 3.000000000146905e-15 14.52287874525907 1.4626048645381418 AHS(ph)DSNLSASAAER ddPTM_PC-9_AZD4547_30min_R2 1 AHSDSNLSASAAER 14 0 Q6PEV8 Q6PEV8 FAM199X Protein FAM199X 1 AHS(0.99)DS(0.01)NLSASAAER 82.34899999999999 0.016416 0.0 9778.8 9272.6 13887.0 12656.0 16584.0 13848.0 10388.0 20064.0 9990.2 13754.0 True False 12888.254988324361 12269.786614424029 13702.8493063954 9738.354733250819 14281.59786067729 12982.082370866923 11312.511875777484 16963.569824852737 10518.261576602481 13272.476646391788 0.9710512462516271 0.924453434074013 1.0324259496904529 0.7337255127812379 1.0760311162091845 0.9781205660961694 0.8523286329422826 1.2781013127240572 0.7924867269939361 1.0 13.696149982516884 AHS(ph)GAAPWQPLAAPSGASAQAAEQLQR ddPTM_PC-9_AZD4547_30min_R2 2 AHSGAAPWQPLAAPSGASAQAAEQLQR 27 0 D3YTB5;P51617-4;P51617-2;P51617-3;P51617;H7C3C1;H7C2I6;H7C224 D3YTB5 IRAK1 Interleukin-1 receptor-associated kinase 1 1 AHS(1)GAAPWQPLAAPSGASAQAAEQLQR;AHS(1)GAAPWQPLAAPSGASAQAAEQLQR 109.51 6.5309000000000004e-06 18099000.0 55574.0 54719.0 86999.0 116922.0 98056.0 90638.0 79150.0 104470.0 88596.0 101791.0 True False 73245.37598899017 72405.8466616341 85845.33641586319 89967.43932689249 84442.61696976444 84970.39153167508 86194.19666613267 88326.56198177663 93279.00368768115 98227.32807276929 0.7456720795126194 0.7371252795148212 0.8739455516113275 0.9159104812485822 0.8596652136074312 0.8650382047318529 0.8774971116212978 0.899205584787383 0.9496237505165335 1.0 16.58383683576089 -1.846985397036341 0.19454594243793696 0.9797957951229469 2.450943674125834e-25 0.7703509736420898 0.036952863398814526 26.141596357618248 0.3464761147793229 0.08136882176966521 7.543451390689061 0.01422376613115674 1.846985397036341 -0.9797957951229469 AHS(ph)GAAPWQPLAAPSGASAQAAEQLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AHSGAAPWQPLAAPSGASAQAAEQLQR 27 0 D3YTB5;P51617-4;P51617-2;P51617-3;P51617;H7C3C1;H7C2I6;H7C224 D3YTB5 IRAK1 Interleukin-1 receptor-associated kinase 1 1 AHS(1)GAAPWQPLAAPSGASAQAAEQLQR 96.382 1.5629999999999999e-09 11073000.0 32456.0 32271.0 37109.0 39294.0 53857.0 41311.0 44173.0 40228.0 42986.0 33505.0 True False 37950.15976478006 35474.651608390915 37993.81929666621 37092.484572866844 43304.10746570939 39144.5784361408 39988.61365517473 39172.05762508922 43614.58892847765 39579.191274565914 0.9588412128361832 0.8962955145368868 0.9599443059131306 0.9371713614750623 1.094112994004937 0.9890191581881967 1.0103443846987323 0.9897134419283012 1.101957557088968 1.0 15.272454513509073 -6.224547337152265 22.599487379672023 1.0272259661591971 0.9366425329064006 0.5532750534090807 0.04076247392795194 141.31813301490988 86568.69827979 0.011638630234709168 0.015024487730507049 5.962833227089552e-07 6.224547337152265 -0.0905834332527965 AHS(ph)GAAPWQPLAAPSGASAQAAEQLQR ddPTM_PC-9_Lapatinib_30min_R1 2 AHSGAAPWQPLAAPSGASAQAAEQLQR 27 0 D3YTB5;P51617-4;P51617-2;P51617-3;P51617;H7C3C1;H7C2I6;H7C224 D3YTB5 IRAK1 Interleukin-1 receptor-associated kinase 1 1 AHS(1)GAAPWQPLAAPSGASAQAAEQLQR;AHS(1)GAAPWQPLAAPSGASAQAAEQLQR 87.792 2.3188000000000002e-05 0.0 150504.0 110870.0 151381.0 121072.0 160950.0 153991.0 147159.0 144761.0 177682.0 139061.0 True False 148357.78536094681 110613.28732683265 138935.0385275587 129976.03876435198 151483.23743987497 147405.1639005539 154778.17296548293 151487.1245360123 157669.5820855915 163097.50856286468 0.9096263129228823 0.6782034152544864 0.8518526110655287 0.796922282318333 0.928789401963715 0.9037855035274049 0.9489916451165462 0.9288132349221188 0.9667197462113223 1.0 17.3153752184029 -6.365092309779639 1.3496269259629554 0.9524269074893662 0.7939482398073205 0.5519084681182618 0.05987635623885387 0.3055252788301744 1.1322397694062458 0.022608460691827186 0.029026306783972187 4.3142736671047993e-07 6.365092309779639 -0.15847866768204566 AHS(ph)IAGFSPECPEDPVGQNVVK ddPTM_PC-9_AZD4547_30min_R2 2 AHSIAGFSPECPEDPVGQNVVK 22 0 E7EV07 E7EV07 ARHGEF4 1 AHS(0.999)IAGFS(0.001)PECPEDPVGQNVVK;AHS(1)IAGFSPECPEDPVGQNVVK 153.57 4.9366e-06 26420000.0 98240.0 90517.0 154004.0 217355.0 175097.0 153391.0 142836.0 183230.0 142715.0 167560.0 True False 129478.27648105928 119774.85009358953 151961.80633557396 167247.16285127445 150787.80394422423 143799.43652149383 155548.12729000277 154916.01370652718 150258.62354155304 161693.77540129484 0.8007622814157038 0.7407511501066131 0.9398123456418289 1.0343450911217646 0.9325516926671793 0.8893319248969821 0.9619920550680465 0.9580827296663309 0.9292789606070994 1.0 17.302904616015653 -5.290065188665311 7.954815660286965 0.9542370829112854 0.7707265763009592 0.7749309320424895 0.039860914723765885 0.10089754137456375 25.352349872765423 0.010644439255120564 0.022851342691097315 5.127844080189272e-06 5.290065188665311 -0.1835105066103262 AHS(ph)IAGFSPECPEDPVGQNVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AHSIAGFSPECPEDPVGQNVVK 22 0 E7EV07 E7EV07 ARHGEF4 1 AHS(0.999)IAGFS(0.001)PECPEDPVGQNVVK 110.13 1.0277e-05 8196200.0 26641.0 22282.0 23793.0 32584.0 30905.0 29444.0 29524.0 35917.0 32315.0 22188.0 True False 31150.79511626523 24494.00970339212 24360.315355454994 30758.424118753315 24849.3871033988 27899.90480680036 26727.272984750383 34974.21680720718 32787.54574102627 26210.50875988864 1.18848494707348 0.934511036309094 0.9294102445174549 1.1735149592298109 0.9480696208929437 1.0644549124318066 1.0197159173671813 1.3343585631092412 1.2509312978770877 1.0 14.67785773696415 -7.740056088502398 24.99646976594462 1.2194837015017304 1.0317094027401 0.27236684553584145 0.11626266100513209 241.71699107083538 282560.9109903131 0.05238122470346337 0.030205795230851654 1.819465862058609e-08 7.740056088502398 -0.18777429876163043 AHS(ph)IAGFSPECPEDPVGQNVVK ddPTM_PC-9_Lapatinib_30min_R1 1 AHSIAGFSPECPEDPVGQNVVK 22 0 E7EV07 E7EV07 ARHGEF4 1 AHS(0.999)IAGFS(0.001)PECPEDPVGQNVVK 129.08 5.4352999999999994e-06 10737000.0 25723.0 18030.0 30439.0 27197.0 29498.0 27996.0 25623.0 24444.0 29706.0 22887.0 True False 25356.185302979535 17988.252642759897 27936.422917937896 29197.158106532373 27762.98563529936 26798.67634186349 26949.633565698132 25579.757477209252 26360.197461952157 26842.98745498946 0.9446111520000147 0.6701285642264202 1.0407344921939825 1.0877015144268278 1.0342733155857768 0.9983492480782823 1.0039729598237714 0.9529400376951932 0.9820142972593178 1.0 14.712257622870412 -5.282122712938419 24.99433474631583 1.0134712483191846 0.8073698448357068 0.5762075484098195 0.07036365420132723 462.0324037353355 558332.6449390036 0.017824004268072347 0.03716528257769826 5.2224860315985815e-06 5.282122712938419 -0.20610140348347772 AHS(ph)LLFENSDSFSEDSSTLGR ddPTM_PC-9_AZD4547_30min_R2 2 AHSLLFENSDSFSEDSSTLGR 21 0 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 AHS(1)LLFENSDSFSEDSSTLGR;AHS(1)LLFENSDSFSEDSSTLGR 174.85 9.9547e-13 9457700.0 15523.2 13744.3 22761.0 31304.0 29519.0 22705.0 20630.6 34021.0 21414.0 21357.3 True False 20459.254697381766 18186.87619056448 22459.174268226794 24087.346441978803 25420.79638502973 21285.252760725998 22466.683433232087 28763.836174806343 22545.900322452555 20609.587427656195 0.9927056894854336 0.8824473684591736 1.0897440012840152 1.1687447177936114 1.2334451853663664 1.0327840300268758 1.0901083542838823 1.3956531772299279 1.0939520454542435 1.0 14.33102800417276 -5.438033180824721 4.008380523305864 1.1570178658443842 0.9394406216869365 0.356829334878503 0.10863825712917036 0.22733510646018595 6.647418777380902 0.029116608313620958 0.06353858560245679 3.6472608017860332e-06 5.438033180824721 -0.2175772441574476 AHS(ph)LLFENSDSFSEDSSTLGR ddPTM_PC-9_Lapatinib_30min_R1 2 AHSLLFENSDSFSEDSSTLGR 21 0 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 AHS(1)LLFENSDSFSEDSSTLGR;AHS(1)LLFENSDSFSEDSSTLGR 167.98 9.7689e-09 6540700.0 30915.7 29295.0 37559.0 22013.7 30258.0 25483.9 29031.0 28348.0 29979.0 18021.6 True False 30474.83644875497 29227.16922737944 34471.04400193269 23632.66093355047 28478.283929516838 24394.013002872383 30534.08313022606 29665.15156946196 26602.4493271347 21136.609547727443 1.44180344439544 1.3827747142408595 1.6308691289440476 1.1180913798017997 1.3473439940881509 1.1541119188387132 1.444606480584253 1.4034962183729929 1.2585958626460472 1.0 14.367456356981275 -13.821748881634152 0.16456010452974495 2.345214298376535e-10 1.445597193335457 0.39572259970454093 0.13754650105288702 113.90556463383486 1.3042198335898685 38.340915185104436 0.5683519578057236 1.5074784705505586e-14 13.821748881634152 1.4455971931009355 AHS(ph)PAEGASVESSSPGPK ddPTM_PC-9_AZD4547_30min_R2 1 AHSPAEGASVESSSPGPK 18 0 C9J4C4;Q8NFG4-3;Q8NFG4-2;Q8NFG4 C9J4C4 FLCN Folliculin 1 AHS(0.998)PAEGAS(0.002)VESSSPGPK 65.598 0.0083833 24641000.0 42671.0 37584.0 67414.0 98096.0 80440.0 73504.0 61667.0 84097.0 50735.0 63834.0 True False 56239.49038806283 49732.29300482201 66520.0463124749 75481.48276809197 69272.29449547046 68907.78326026886 67155.24353519162 71101.74100681022 53416.748522444694 61599.191089557426 0.9129907291525587 0.8073530207972626 1.07988506238277 1.2253648373133903 1.1245650027247487 1.1186475348367102 1.0901968410194933 1.1542641997268648 0.8671663958181448 1.0 15.910623785360105 -5.2844642735774805 11.476381113650422 1.096226849132869 0.8601830818581891 0.4658649176073022 0.09431950332494132 0.6797775559824902 338.6703843315721 0.02420684206256323 0.05128456846856431 5.194404025417522e-06 5.2844642735774805 -0.2360437672746799 AHS(ph)PAEGASVESSSPGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AHSPAEGASVESSSPGPK 18 0 C9J4C4;Q8NFG4-3;Q8NFG4-2;Q8NFG4 C9J4C4 FLCN Folliculin 1 AHS(1)PAEGASVESSSPGPK 138.98 0.00012869 8013700.0 11013.0 9948.6 10838.0 12537.0 13974.0 10857.0 14307.0 11875.0 14654.0 8822.7 True False 12877.28338333505 10936.231259993127 11096.419023343891 11834.592535502406 11235.895013198342 10287.639807343832 12951.737386289917 11563.293832602541 14868.287027355696 10422.185669545232 1.2355645726945628 1.0493222445604662 1.0646921265055604 1.1355192577392266 1.0780747311027914 0.987090437028525 1.2427083720199221 1.1094883740549502 1.4265997074685073 1.0 13.347370241038357 -7.2835692618624925 24.923582220536062 1.203823149315233 1.0899271929922951 0.1540316169041993 0.11742006873960592 1349.516826337614 1519874.1160379553 0.04631239981392546 0.031248313106330066 5.2051199023619786e-08 7.2835692618624925 -0.11389595632293781 AHS(ph)PALGVHSFSGVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AHSPALGVHSFSGVQR 16 0 Q9H1A4 Q9H1A4 ANAPC1 Anaphase-promoting complex subunit 1 1 AHS(1)PALGVHSFSGVQR 89.353 0.007701 0.0 3626.9 5604.2 5715.2 4465.1 10932.0 3135.5 3637.3 4516.9 4378.4 5307.8 True False 4240.862535459722 6160.54793913249 5851.472043016701 4214.934923049519 8789.953076018628 2971.068860267714 3292.748612228443 4398.336161051149 4442.425816880999 6270.06212347832 0.6763669086434986 0.9825337959673871 0.9332398830795944 0.6722317642223427 1.401892501687431 0.47384998772859244 0.5251540650448594 0.701482070581331 0.7085138439452273 1.0 12.614264021914297 AHS(ph)PASLSFASYR ddPTM_PC-9_AZD4547_30min_R2 3 AHSPASLSFASYR 13 0 Q9UKK3 Q9UKK3 PARP4 Poly [ADP-ribose] polymerase 4 1 AHS(1)PASLSFASYR;AHS(1)PASLSFASYR;AHS(1)PASLSFASYR 151.49 7.5917e-05 25454900.0 21188.7 20722.3 63341.0 113486.0 83701.0 62579.0 39410.0 86854.0 44525.0 60462.0 True False 27926.26584766109 27420.37822833713 62501.05695372582 87323.55604122167 72080.56093442769 58665.92523732537 42917.413652713774 73432.71000636746 46878.500600410924 58345.243783200545 0.4786382580117345 0.4699676691767004 1.0712279682293806 1.496669657696501 1.2354145130023775 1.005496274131897 0.7355769017297528 1.2585894795337385 0.8034673875835058 1.0 15.832327433938577 -5.265972514251527 7.5623372801259245 1.0916461277721519 0.4724042265972507 0.5681958599352697 0.20941061222731785 0.08396942688458052 42.45719124666181 0.057478978491253954 0.13275057902452114 5.420351937883546e-06 5.265972514251527 -0.6192419011749012 AHS(ph)PASLSFASYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AHSPASLSFASYR 13 0 Q9UKK3 Q9UKK3 PARP4 Poly [ADP-ribose] polymerase 4 1 AHS(1)PASLSFASYR;AHS(0.962)PAS(0.028)LS(0.005)FAS(0.004)YR;AHS(1)PASLSFASYR;AHS(1)PASLSFASYR 143.93 5.0328e-05 23164400.0 30041.9 32476.1 71414.2 70858.0 92444.0 81882.5 62245.5 46182.6 62667.2 49057.0 True False 35127.40031542846 35700.11258093226 73116.9853678618 66888.05598473556 74330.26181480648 77588.437554097 56349.15562160548 44970.35568450944 63583.58924530535 57950.645765001645 0.6061606363779829 0.6160433953695951 1.261711313181252 1.154224514701293 1.282647688107335 1.3388709742550495 0.9723645850317106 0.7760112953162044 1.0972024281342112 1.0 15.822537117343312 -5.250190885509184 24.34884557320749 1.1133291917801158 0.6111018713602835 0.614625558822778 0.15812474717536462 370.4761340230681 801938.5979498075 0.04530549358791042 0.1173923631836367 5.620942135462403e-06 5.250190885509184 -0.5022273204198323 AHS(ph)PASLSFASYR ddPTM_PC-9_Lapatinib_30min_R1 1 AHSPASLSFASYR 13 0 Q9UKK3 Q9UKK3 PARP4 Poly [ADP-ribose] polymerase 4 1 AHS(1)PASLSFASYR 135.86 2.9908000000000002e-05 7877800.0 17300.0 12045.0 35307.0 15139.0 19789.0 26861.0 15762.0 15000.0 31363.0 12878.0 True False 17053.298827568546 12017.1105425426 32404.194748961323 16252.372562223547 18625.049926670916 25712.21764604929 16578.07923594169 15696.954760192215 27830.56867296862 15103.945141143633 1.129062550758001 0.7956272636218469 2.1454126353181233 1.0760349306322334 1.2331248394126961 1.7023511013694284 1.0975992749591275 1.0392619023379002 1.8426026056700415 1.0 13.882637809376158 AHS(ph)PASTLPNSPGSTFER ddPTM_PC-9_AZD4547_30min_R2 1 AHSPASTLPNSPGSTFER 18 0 A0A3B3IUC2;A2A2Y8;A0A3B3ITM2;Q9UMD9-2;Q9UMD9 A0A3B3IUC2 COL17A1 Collagen alpha-1(XVII) chain;120 kDa linear IgA disease antigen;97 kDa linear IgA disease antigen 1 AHS(0.729)PAS(0.081)T(0.02)LPNS(0.026)PGS(0.072)T(0.072)FER 99.915 0.005333600000000001 0.0 3786.6 5878.4 8541.1 11185.0 11321.0 7995.9 8903.8 13202.0 9163.1 9684.2 True False 4990.660033827162 7778.477841622646 8427.839433344401 8606.471056527376 9749.274564684494 7495.915108984324 9696.220951053865 11161.9342517796 9647.44275916059 9345.159105641074 0.5340369251513994 0.8323537088766394 0.9018401225782292 0.9209550056062931 1.043243293610644 0.8021174411529837 1.0375661710458066 1.1944081556665904 1.0323465497058308 1.0 13.190003511389644 -4.307054987650468 0.6350191954553666 1.0338299626467267 3.378327548337355e-30 0.7040872232191661 0.09315087361989871 3.552165260895733 0.7037957665518161 0.04534899282729491 3.0531998284003046 4.931113653259207e-05 4.307054987650468 -1.0338299626467267 AHS(ph)SPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLR ddPTM_PC-9_AZD4547_30min_R2 1 AHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLR 37 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 AHS(0.68)S(0.22)PAS(0.1)LQLGAVSPGTLTPTGVVSGPAATPTAQHLR 115.63 4.6445e-26 13604000.0 0.0 1423.2 7549.9 29700.0 14665.0 6672.4 4754.3 15636.0 4488.2 12504.0 True False 0.0 1883.2215678071173 7449.783392982974 22853.123860425825 12629.017886326117 6255.17377320714 5177.42348970051 13219.815479535351 4725.4370891580975 12066.238765921385 0.0 0.15607362031703617 0.6174072581775323 1.8939724551920671 1.046640807572463 0.5184029501283858 0.4290834608977803 1.0956036703725776 0.3916246960489564 1.0 13.558688415261429 -5.334189105509009 3.8756994394006514 0.9043356618672543 0.0647257043580429 0.382782270888694 0.4145401513827564 0.2393319686703051 6.911532155965279 0.11798425883478325 0.27740526533972765 4.632451642653195e-06 5.334189105509009 -0.8396099575092114 AHS(ph)SPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLR 37 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 AHS(0.431)S(0.431)PAS(0.137)LQLGAVSPGTLTPTGVVSGPAATPTAQHLR 66.66 4.2277e-06 8490300.0 3755.0 3955.3 8319.4 4780.2 7115.3 8130.9 6045.3 6563.7 6462.5 5025.5 True False 4390.647335369393 4347.956044332948 8517.766047500201 4512.380891617498 5721.108042608429 7704.501290368607 5472.64541981816 6391.409829815009 6557.001836651164 5936.58336816389 0.7395916241848995 0.7324004018287232 1.4347926272169305 0.7600972835345055 0.9637038154452627 1.2978005719056402 0.9218510177362809 1.0766141791405166 1.1045076654384056 1.0 12.535417152396409 -5.1147211347469455 21.87576674171829 1.0621903709580507 0.7356691046649638 0.3566864108156129 0.17913673153658663 7.656638847986418 1435.6476610124912 0.04370963747111214 0.1156454612012975 7.678543788235835e-06 5.1147211347469455 -0.32652126629308686 AHS(ph)SPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLR ddPTM_PC-9_Lapatinib_30min_R1 2 AHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLR 37 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 AHS(0.566)S(0.223)PAS(0.211)LQLGAVSPGTLTPTGVVSGPAATPTAQHLR;AHS(0.426)S(0.426)PAS(0.149)LQLGAVSPGTLTPTGVVSGPAATPTAQHLR 77.242 2.5047e-09 16655800.0 8741.7 3045.54 26755.1 7330.4 11753.6 15792.3 7562.7 10764.0 24214.5 6902.9 True False 8617.04175496856 3038.48823924742 24555.398955672674 7869.502069497554 11062.276356466695 15116.900142649336 7954.259601424701 11264.134735913936 21487.208020010778 8096.057067463919 1.0643504218366187 0.37530469633895785 3.0330071479306686 0.9720166253673241 1.3663782584887263 1.8671928837310787 0.9824856143110616 1.3913111829685278 2.6540336661364 1.0 12.983003743994832 AHS(ph)VDVEK ddPTM_PC-9_Lapatinib_30min_R1 1 AHSVDVEK 8 0 Q6IQ19-2;Q6IQ19 Q6IQ19-2 CCSAP Centriole, cilia and spindle-associated protein 1 AHS(1)VDVEK 99.568 0.0029241 1750700.0 34203.0 32331.0 41389.0 43185.0 42316.0 43673.0 40428.0 30890.0 45437.0 38418.0 True False 33715.258947937975 32256.139555910726 37986.15618616024 46360.96896093689 39827.056076456945 41805.20759673542 42521.16402427677 32325.262169489193 40319.40658717834 45058.50011123278 0.7482552429554349 0.7158724652680901 0.8430408489493982 1.0289061741178422 0.8838966227934499 0.9277984729525797 0.9436879594151544 0.7174065290608891 0.8948235402342428 1.0 15.459511670084593 -5.418755334718161 4.388540852873281 0.9046687487802428 0.7346680288333505 0.4468057589573119 0.07952374429359271 0.2157337894131857 6.867922496165552 0.02191092084468034 0.04759568411771572 3.812805621207315e-06 5.418755334718161 -0.17000071994689236 AHSENEGTALPS(ph)ADSCTSPTKMDLSYSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AHSENEGTALPSADSCTSPTKMDLSYSK 28 1 Q8IVL0-3;Q8IVL0-2;Q8IVL0;F8VZV4 Q8IVL0-3 NAV3 Neuron navigator 3 1 AHSENEGTALPS(0.477)ADS(0.477)CT(0.022)S(0.022)PT(0.002)KMDLSYSK 74.905 1.4324e-05 6104200.0 20185.0 15502.0 24352.0 36532.0 39255.0 39723.0 34166.0 50003.0 42860.0 28456.0 True False 23601.921828077568 17040.936110851108 24932.64403547429 34485.23047834203 31563.26454437533 37639.85595165506 30929.549139580715 48690.47423255785 43486.74641684625 33614.847542427924 0.7021278855508043 0.5069467023267742 0.741715219859464 1.0258928122406485 0.9389679517224307 1.119739005335272 0.9201157048397175 1.4484811859135103 1.2936767409686516 1.0 15.036810985900647 -5.94451993920208 0.6760346285445304 1.2151890041534241 0.5169162032629868 0.6576298847435565 0.15501870104734466 0.601946151059099 0.5162696904001643 0.09158502367190892 0.2623231654653159 1.1362661285493512e-06 5.94451993920208 -0.6982728008904373 AHSENEGTALPSADS(ph)CTSPTKMDLSYSK ddPTM_PC-9_AZD4547_30min_R2 1 AHSENEGTALPSADSCTSPTKMDLSYSK 28 1 Q8IVL0-3;Q8IVL0-2;Q8IVL0;F8VZV4 Q8IVL0-3 NAV3 Neuron navigator 3 1 AHSENEGTALPS(0.123)ADS(0.529)CT(0.165)S(0.165)PT(0.01)KMDLS(0.004)Y(0.001)S(0.002)K 68.97 9.0066e-05 8548800.0 17389.0 9606.5 18017.0 32019.0 23009.0 18749.0 17906.0 18665.0 18053.0 24005.0 True False 22918.34028633086 12711.613259653648 17778.08280790133 24637.514238618696 19814.59751425011 17576.62206610226 19499.599311481663 15780.753129030914 19007.244724070035 23164.592256553333 0.9893694666629494 0.5487518674565702 0.7674679791901736 1.063585059721855 0.8553829609776317 0.7587710533143436 0.8417846986262048 0.6812445889077323 0.8205300794229533 1.0 14.499633667807721 -11.840960172051957 1.9374018868783687 1.7905474083536024 0.8087544333084848 0.14029119039286908 0.13748720945316467 9794490.822395315 1182860.9024448502 33856319.11746997 0.03535699361434934 1.442247610007159e-12 11.840960172051957 -0.9817929750451175 AHSENEGTALPSADS(ph)CTSPTKMDLSYSK ddPTM_PC-9_Lapatinib_30min_R1 2 AHSENEGTALPSADSCTSPTKMDLSYSK 28 1 Q8IVL0-3;Q8IVL0-2;Q8IVL0;F8VZV4 Q8IVL0-3 NAV3 Neuron navigator 3 1 AHSENEGTALPS(0.008)ADS(0.737)CT(0.236)S(0.018)PT(0.001)KMDLSYSK;AHSENEGTALPS(0.099)ADS(0.291)CT(0.291)S(0.291)PT(0.027)KMDLSYSK 94.837 7.7425e-10 17679200.0 62842.0 44880.0 65330.0 58434.0 71546.0 56222.0 43467.0 49664.0 76830.0 50040.0 True False 61945.861556188596 44776.08311741898 59958.819581092794 62731.431290109686 67337.80494484802 53817.51611988317 45717.508574335596 51971.570747345744 68176.596344233 58689.34732589122 1.055487313774586 0.7629337376813133 1.0216303692755762 1.0688725322122516 1.1473599215703234 0.9169895146566265 0.7789745610983647 0.885536696442663 1.1616519769023979 1.0 15.840811043791176 -5.090336934710093 0.003366156072743546 1.9305437839934911 0.00010604422591402737 0.0017076951355868841 0.1329874407656086 815840.9598124113 475.0935955654192 133241.78004585102 139258.2696513774 8.122001498669166e-06 5.090336934710093 -1.9304377397675772 AHSEPLALCGET(ph)APRDSPPASEAPASEPGYVNYTK ddPTM_PC-9_AZD4547_30min_R2 1 AHSEPLALCGETAPRDSPPASEAPASEPGYVNYTK 35 1 Q66K64;K7ELE9 Q66K64 DCAF15 DDB1- and CUL4-associated factor 15 1 AHS(0.1)EPLALCGET(0.624)APRDS(0.136)PPAS(0.136)EAPAS(0.004)EPGYVNYTK 55.442 0.00045028 10764000.0 27970.0 28025.0 45331.0 58055.0 48133.0 49180.0 33974.0 53513.0 43659.0 43368.0 True False 36863.87818785866 37083.53319125522 44729.88132125077 44671.31669080883 41450.563786057646 46104.766825479186 36997.620183641135 45243.7954564067 45966.725608384964 41849.69952019184 0.8808636289030558 0.8861122927146223 1.0688220425494162 1.0674226387039076 0.9904626379947694 1.1016749786515037 0.8840593984621168 1.0811020383689316 1.098376479052298 1.0 15.35292964384752 -5.252840496541599 24.14535061551315 1.0357315121336141 0.8834879170292885 0.49131434986052835 0.06226953240123965 321.5365469818756 902853.7432573966 0.01567718803002429 0.04003978576162679 5.586753419146736e-06 5.252840496541599 -0.1522435951043256 AHSEPLALCGET(ph)APRDSPPASEAPASEPGYVNYTK ddPTM_PC-9_Lapatinib_30min_R1 1 AHSEPLALCGETAPRDSPPASEAPASEPGYVNYTK 35 1 Q66K64;K7ELE9 Q66K64 DCAF15 DDB1- and CUL4-associated factor 15 1 AHSEPLALCGET(0.541)APRDS(0.453)PPAS(0.006)EAPASEPGYVNYTK 106.37 2.5544000000000003e-21 9344600.0 34917.0 36627.0 39302.0 32122.0 34893.0 32031.0 27196.0 28274.0 37033.0 26226.0 True False 34419.077177006424 36542.192431856165 36070.74127010728 34484.35903585074 32840.66234227746 30661.108797907906 28604.075808949994 29587.713259311662 32861.95356522165 30759.12915605161 1.1189873745250276 1.1880112810237602 1.172684086311678 1.1211097317124865 1.0676720454491906 0.9968132921564061 0.9299377646171876 0.9619164804440024 1.0683642374431894 1.0 14.908727038244818 -6.431931788748212 1.8123326712260537 0.984067578300182 1.1606358653107913 0.7999048624359638 0.03755661569910733 0.14903905373546023 0.9759041268487576 0.014353384137269139 0.01670525459688866 3.698862703738719e-07 6.431931788748212 0.17656828701060934 AHSEPLALCGETAPRDS(ph)PPASEAPASEPGYVNYTK ddPTM_PC-9_AZD4547_30min_R2 1 AHSEPLALCGETAPRDSPPASEAPASEPGYVNYTK 35 1 Q66K64;K7ELE9 Q66K64 DCAF15 DDB1- and CUL4-associated factor 15 1 AHSEPLALCGET(0.011)APRDS(0.572)PPAS(0.412)EAPAS(0.004)EPGY(0.001)VNYTK 71.501 2.5643e-06 9870700.0 29668.0 30396.0 48899.0 53679.0 52549.0 46794.0 39749.0 61559.0 37646.0 53762.0 True False 39101.80686726461 40220.91257382316 48250.56730996099 41304.13588228278 45253.478411766184 43867.96378266513 43286.583995983725 52046.471035093185 39635.89070416775 51879.80874387926 0.7536999039511265 0.7752710263907515 0.9300452040632003 0.7961505040659159 0.872275351576063 0.8455691114674867 0.8343628290860006 1.0032124692678939 0.7639945416885132 1.0 15.662885540620065 -14.522875458344217 0.0222360665412999 2.1245145871713054 8.81933187515164e-09 0.34367545677707767 0.07143026675930639 2939.575403814195 4.924930492886553 328.01541420198555 167.40396225170628 3.0000227054362623e-15 14.522875458344217 -2.1245145783519734 AHSEPLALCGETAPRDS(ph)PPASEAPASEPGYVNYTK ddPTM_PC-9_Lapatinib_30min_R1 1 AHSEPLALCGETAPRDSPPASEAPASEPGYVNYTK 35 1 Q66K64;K7ELE9 Q66K64 DCAF15 DDB1- and CUL4-associated factor 15 1 AHS(0.001)EPLALCGET(0.11)APRDS(0.392)PPAS(0.392)EAPAS(0.1)EPGY(0.004)VNY(0.001)TK 58.137 0.0002125 10177000.0 15888.0 18145.0 19479.0 19096.0 17722.0 15534.0 14981.0 13242.0 18785.0 14686.0 True False 15661.434206497634 18102.986367325477 17877.51181111443 20500.383542388583 16679.626802792558 14869.647031522638 15756.64287740403 13857.271662297693 16669.23548518047 17224.455532135056 0.9092556903919924 1.0510048537413201 1.0379144802435694 1.1901905116328202 0.9683688852558485 0.8632869122499033 0.9147832190113308 0.8045114480654946 0.9677655966588475 1.0 14.072170759372865 -6.518834267601801 20.23395487529077 0.900110358329248 1.0507859830840172 0.3882005480523797 0.08055789984781968 13.513863953608265 67613.52077208823 0.025874225115097307 0.026637401367130064 3.028068757892925e-07 6.518834267601801 0.15067562475476914 AHSEVFTKPSGQQTLS(ph)PDR ddPTM_PC-9_AZD4547_30min_R2 2 AHSEVFTKPSGQQTLSPDR 19 1 F5H212;P15822;A0A0D9SFF3;P15822-2;P15822-3 F5H212 HIVEP1 Zinc finger protein 40 1 AHSEVFTKPS(0.003)GQQT(0.126)LS(0.871)PDR;AHSEVFT(0.001)KPS(0.014)GQQT(0.092)LS(0.893)PDR 71.946 0.0025081 9653000.0 19242.4 17489.4 24831.9 24927.6 24261.5 24462.2 18650.1 30180.3 23345.5 28425.9 True False 25361.08293321601 23142.506526142355 24502.61278112478 19180.92694758084 20893.20950897383 22932.57476694259 20309.92276996896 25516.628109300396 24579.495469217145 27430.717893170568 0.9245504631699838 0.8436711943256925 0.8932545213198814 0.699249907431563 0.7616719908805455 0.8360180311814631 0.7404079925675415 0.930220937296478 0.8960573166529013 1.0 14.743504759204258 -7.823619409869677 10.63354009932885 0.9352857570083728 0.8127389480215081 0.4217355602028874 0.06852198759897023 0.5371236902605797 88.67694466792072 0.03890894330821761 0.018688166426502457 1.5009996470792928e-08 7.823619409869677 -0.12254680898686465 AHSEVFTKPSGQQTLS(ph)PDR ddPTM_PC-9_Lapatinib_30min_R1 1 AHSEVFTKPSGQQTLSPDR 19 1 F5H212;P15822;A0A0D9SFF3;P15822-2;P15822-3 F5H212 HIVEP1 Zinc finger protein 40 1 AHSEVFTKPSGQQT(0.106)LS(0.893)PDR 109.12 7.1899e-05 6948600.0 20948.0 23560.0 24031.0 16772.0 22204.0 23576.0 21826.0 20136.0 21131.0 20063.0 True False 20649.277678607286 23505.448267522093 22055.263942342583 18005.46882975184 20898.004374743607 22567.709438340273 22956.04348456181 21071.592070082046 18751.00426070529 23530.86281773291 0.877540183653867 0.9989199482225674 0.9372909150497316 0.7651852364794239 0.8881104163760126 0.9590685056109884 0.9755716848284071 0.8954874384887599 0.7968685383935218 1.0 14.522266601090948 -10.332153876799183 24.995748306497553 0.9999999999997723 0.9029930214616915 0.15261134557296008 0.07068911320112625 0.0 0.0 0.07211434664447655 0.017490298137504905 4.6542115887551854e-11 10.332153876799183 -0.09700697853808082 AHSLGGLDPAFTS(ph)TEDLNCK ddPTM_PC-9_Lapatinib_30min_R1 2 AHSLGGLDPAFTSTEDLNCK 20 0 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 AHSLGGLDPAFT(0.205)S(0.764)T(0.03)EDLNCK;AHSLGGLDPAFT(0.147)S(0.558)T(0.296)EDLNCK 116.45 1.011e-05 6746600.0 35986.8 52260.0 51842.0 48337.0 52339.0 49195.0 53374.0 56443.0 47831.0 45213.0 True False 35473.62163282913 52138.99518084481 47579.75087590709 51891.864227505044 49260.52292243311 47091.04452914616 56137.44455901225 59065.54783530195 42443.76909724072 53028.006807464386 0.6689601168987508 0.9832350548296597 0.8972570107841508 0.9785746693424763 0.9289529418160037 0.8880410063332321 1.058637650908466 1.113855703642772 0.8004028748684969 1.0 15.694466901683986 -4.75902929706959 24.99831849144533 0.9628809422595397 0.6689597327638294 0.5177656757336733 0.08453336179057827 52.533226735981714 544777.574389746 0.020816292874702567 0.13629768721258284 1.741689376812365e-05 4.75902929706959 -0.2939212094957103 AHSPAEGASVES(ph)SSPGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AHSPAEGASVESSSPGPK 18 0 C9J4C4;Q8NFG4-3;Q8NFG4-2;Q8NFG4 C9J4C4 FLCN Folliculin 1 AHSPAEGAS(0.032)VES(0.625)S(0.185)S(0.158)PGPK 49.343 0.043354000000000004 6232300.0 17146.0 14124.0 23025.0 31044.0 29717.0 32590.0 33064.0 24218.0 24883.0 21365.0 True False 20048.479151063544 15526.137377735851 23574.00332279876 29304.70532600594 23894.167175269442 30880.92302858389 29931.93855736982 23582.303161092044 25246.866800988926 25238.305374753058 0.7943670881769616 0.6151814532392219 0.9340565054887097 1.1611201659886672 0.9467421374167136 1.2235735549612368 1.1859725965322538 0.9343853642678568 1.000339223498121 1.0 14.623327423407272 -5.462956134982948 4.379759123165756 1.068180443326285 0.7098917677580727 0.6572094881653903 0.10278838258964408 0.12532944092643358 4.817436510596191 0.028085947731922377 0.05954354140667652 3.4438471287331327e-06 5.462956134982948 -0.3582886755682122 AHSPAEGASVESSS(ph)PGPK ddPTM_PC-9_AZD4547_30min_R2 2 AHSPAEGASVESSSPGPK 18 0 C9J4C4;Q8NFG4-3;Q8NFG4-2;Q8NFG4 C9J4C4 FLCN Folliculin 1 AHSPAEGASVES(0.014)S(0.068)S(0.918)PGPK;AHSPAEGASVES(0.006)S(0.039)S(0.954)PGPK 128.74 2.4001999999999998e-05 14929700.0 99470.0 83251.0 133133.0 166514.0 154893.0 144078.0 122413.0 139004.0 117728.0 166293.0 True False 131099.39089547013 110160.25768796384 131367.56943244315 128126.76991565488 133388.7805977983 135068.77988372074 133307.51985459682 117524.12579415023 123950.86173352454 160471.13268565008 0.8169655731930502 0.6864802151285293 0.8186367680832761 0.7984412384415882 0.8312322494731565 0.8417014177142347 0.8307258609293636 0.7323692668410987 0.7724184385009247 1.0 17.291954267254994 -11.934271416133853 2.2160299682255076 2.6976311991457544 0.7919558828441792 0.6391838130097803 0.04685848070162105 2367777.68468119 239774.96766257248 20187597.12560036 0.01301809016108648 1.163398725960513e-12 11.934271416133853 -1.9056753163015752 AHSPAEGASVESSS(ph)PGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AHSPAEGASVESSSPGPK 18 0 C9J4C4;Q8NFG4-3;Q8NFG4-2;Q8NFG4 C9J4C4 FLCN Folliculin 1 AHSPAEGASVESS(0.03)S(0.97)PGPK 145.17 9.6785e-05 3780800.0 39867.0 46294.0 56290.0 58070.0 71097.0 64697.0 63690.0 64932.0 60658.0 52702.0 True False 46615.695690857945 50889.76237361252 57632.16708101376 54816.52616548018 57166.05322408491 61304.17542744072 57656.82212433108 63227.60380114088 61545.0084963383 62256.45541119754 0.7487688687537064 0.8174214551324971 0.925721946428835 0.8804954571124008 0.9182349500386581 0.9847039158033154 0.9261179703134985 1.015599159694027 0.9885723189641908 1.0 15.925935818446789 -3.064326897918707 0.3412593626011693 1.001234947664789 3.3766409955486425e-12 0.8765735875168398 0.028520064181067523 6.94924216924194 0.2551112577851807 0.025867506209613964 3.634239331650028 0.0008623292193560949 3.064326897918707 -1.0012349476614124 AHSPAEGASVESSS(ph)PGPK ddPTM_PC-9_Lapatinib_30min_R1 2 AHSPAEGASVESSSPGPK 18 0 C9J4C4;Q8NFG4-3;Q8NFG4-2;Q8NFG4 C9J4C4 FLCN Folliculin 1 AHSPAEGASVESS(0.029)S(0.971)PGPK;AHSPAEGASVESS(0.097)S(0.903)PGPK 148.19 2.5065e-05 10192500.0 153375.0 124694.0 158454.0 145197.0 162774.0 146533.0 127688.0 140025.0 159375.0 132808.0 True False 151187.84437446957 124405.27870417628 145426.52377012811 155875.27174299324 153199.95334599697 140266.12517510654 134299.05985781757 146531.07268639465 141424.50920684778 155763.68584446362 0.9706231818720366 0.7986796025641048 0.9336356094920765 1.000716379417479 0.9835408844842909 0.9005059453662903 0.8621974957110392 0.9407267932315873 0.9079427495575954 1.0 17.24899940258181 -5.482135951424155 24.987314465895835 0.9387774884868274 0.8800279236509999 0.13371994655765573 0.05718148399896125 947.3764536206385 581018.8844440345 0.015096358359935568 0.03141844555122171 3.2950654739276163e-06 5.482135951424155 -0.058749564835827495 AHSPAS(ph)TLPNSPGSTFER ddPTM_PC-9_Lapatinib_30min_R1 1 AHSPASTLPNSPGSTFER 18 0 A0A3B3IUC2;A2A2Y8;A0A3B3ITM2;Q9UMD9-2;Q9UMD9 A0A3B3IUC2 COL17A1 Collagen alpha-1(XVII) chain;120 kDa linear IgA disease antigen;97 kDa linear IgA disease antigen 1 AHS(0.302)PAS(0.669)T(0.018)LPNS(0.007)PGS(0.002)T(0.002)FER 120.59 4.3685e-05 4483400.0 12737.0 12192.0 22464.0 10490.0 3719.3 7711.9 9289.8 7481.0 24225.0 2737.6 True False 12555.368044320263 12163.770173074243 20617.09663354765 11261.469593614169 3500.5380864251433 7382.08001431694 9770.780388659503 7828.594570733203 21496.525399440885 3210.7905123772953 3.9103666202826064 3.7884035492767447 6.421190219066204 3.5073822319463894 1.0902418183095093 2.2991471993765136 3.0431074064141104 2.4382140599191096 6.695088115083747 1.0 11.648712824340045 -5.991876816212998 24.93182017353694 2.776158489054971 4.673071762256791 0.22436136998112954 1.618281386675458 284.80656078718437 874122.6533919169 0.45441408248270543 0.6726978806539314 1.0188803434663703e-06 5.991876816212998 1.8969132732018203 AHSS(ph)PASLQLGAVSPGTLTPTGVVSGPAATPTAQHLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLR 37 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 AHS(0.431)S(0.48)PAS(0.088)LQLGAVS(0.001)PGTLTPTGVVSGPAATPTAQHLR 67.72 3.6187e-06 8392500.0 5718.9 11233.0 32100.0 22117.0 28443.0 26873.0 15162.0 12269.0 19994.0 10234.0 True False 6686.996816576306 12348.138003689231 32865.385739927915 20877.856194281463 22869.798329783906 25463.732572787198 13725.745596625979 11946.951750080047 20286.37442506823 12089.34318770057 0.5531315235867825 1.0214068549441093 2.718541878550063 1.7269636464222582 1.8917320796262225 2.1062957827761424 1.135359083079902 0.9882217391458132 1.6780377651704963 1.0 13.561448244848838 -7.291103887035341 24.369848762968942 1.1994229912840946 1.7005845874970353 0.13556581072413942 0.5773694420974391 1127.409757413707 926179.120823981 0.2565067784899453 0.17296872045293116 5.1155945141195427e-08 7.291103887035341 0.5011615962129408 AHSSPAS(ph)LQLGAVSPGTLTPTGVVSGPAATPTAQHLR ddPTM_PC-9_AZD4547_30min_R2 2 AHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLR 37 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 AHS(0.316)S(0.316)PAS(0.349)LQLGAVS(0.008)PGT(0.008)LT(0.003)PTGVVSGPAATPTAQHLR;AHS(0.32)S(0.32)PAS(0.36)LQLGAVSPGTLTPTGVVSGPAATPTAQHLR 64.342 5.559199999999999e-06 30293400.0 14317.1 11188.1 39042.0 100183.0 54612.0 43570.0 14543.1 55972.0 14219.6 40560.0 True False 18869.639985820224 14804.43452977993 38524.27757041039 77087.3571619206 47030.06647173828 40845.56101232465 15837.407726282197 47322.8135086053 14971.21902611125 39140.006745503175 0.4821062016804116 0.3782430244849363 0.9842685470368876 1.9695284587751696 1.201585548452712 1.0435757274624748 0.40463477252981744 1.2090650320095373 0.3825042525786306 1.0 15.256356384152468 -11.476164606891968 4.526484762838185 1.0477634694518398 0.9222775236738849 0.001393174538003139 0.4821394239167542 0.32254871150701875 0.0033287620957265004 0.6479218867323576 0.12093999250426696 3.3406839696403783e-12 11.476164606891968 -0.1254859457779549 AHSTMT(ph)GSGVDAR ddPTM_PC-9_AZD4547_30min_R2 1 AHSTMTGSGVDAR 13 0 Q7Z3C6;H7C152;Q7Z3C6-2 Q7Z3C6 ATG9A Autophagy-related protein 9A 1 AHS(0.003)T(0.034)MT(0.482)GS(0.482)GVDAR 94.781 0.014062999999999999 661510.0 0.0 0.0 3471.2 6853.6 3001.7 3434.8 2154.9 3763.4 2322.7 2603.6 True False 0.0 0.0 3425.169619958213 5273.608407064464 2584.9657681135436 3220.021413016591 2346.681925405554 3181.853004328686 2445.473180113969 2512.448756474163 0.0 0.0 1.3632793947069048 2.0989914295665737 1.0288630808698154 1.2816267017264056 0.9340218061596459 1.2664349854418242 0.9733425104939518 1.0 11.294878456263298 -5.258766790941077 24.999999999989765 1.2660577931122978 2.6387530240695965e-05 0.7063646410862388 0.3203827855391632 121.69349776548623 1138332.7587628628 0.0864382160519542 0.20830863397350327 5.511035505889835e-06 5.258766790941077 -1.2660314055820572 AHSTMT(ph)GSGVDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AHSTMTGSGVDAR 13 0 Q7Z3C6;H7C152;Q7Z3C6-2 Q7Z3C6 ATG9A Autophagy-related protein 9A 1 AHSTMT(0.563)GS(0.437)GVDAR;AHSTMT(0.863)GS(0.137)GVDAR 84.046 0.021698 1111700.0 2182.5 5663.0 8815.3 8945.099999999999 13993.5 10926.099999999999 8088.9 7458.799999999999 6672.6 6460.700000000001 True False 2551.954143660107 6225.185214536821 9025.490184211418 8443.935047405486 11251.57412818027 10353.116081700235 7322.660833435421 7263.014403251853 6770.174151681013 7631.973767126945 0.33437669225909694 0.8156717258843895 1.1825892566725975 1.1063894223242599 1.4742679248510995 1.356545029844575 0.9594714364685292 0.9516561016673952 0.887080375045582 1.0 12.897840497134847 -4.861605600799907 2.306811845970609 1.1287718291382216 0.21390941697451618 0.6476461071222491 0.17708719723586264 0.3313409675279082 2.4547097435639134 0.052658242338745526 0.582503574963807 1.3752903611247323e-05 4.861605600799907 -0.9148624121637055 AHSTMTGS(ph)GVDAR ddPTM_PC-9_AZD4547_30min_R2 1 AHSTMTGSGVDAR 13 0 Q7Z3C6;H7C152;Q7Z3C6-2 Q7Z3C6 ATG9A Autophagy-related protein 9A 1 AHS(0.248)T(0.123)MT(0.026)GS(0.603)GVDAR 84.169 0.038889 0.0 2699.5 794.86 5385.6 14284.0 8140.4 7976.6 3597.5 12019.0 6866.6 7755.7 True False 3557.8848469118498 1051.7829506655173 5314.18342511147 10991.044485600096 7010.245973532165 7477.821941035323 3917.6705307190477 10161.739719143989 7229.554457558264 7484.175303651358 0.47538769504450795 0.14053424832958902 0.7100559793834333 1.468571223904632 0.9366758111761527 0.9991510938268728 0.5234605513325838 1.3577634551379774 0.9659787704372892 1.0 12.869627636232027 -5.509456804538092 7.197833871787448 1.0292765240721673 0.33334424920810435 0.5738485511186955 0.2507519369069427 0.10501478978606957 29.576027216144237 0.06668382521299956 0.12882102395830614 3.094163049400023e-06 5.509456804538092 -0.695932274864063 AHT(ph)FSHPPSSTK ddPTM_PC-9_AZD4547_30min_R2 2 AHTFSHPPSSTK 12 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 AHT(0.986)FS(0.014)HPPSSTK;AHT(0.945)FS(0.055)HPPSSTK 79.61399999999999 0.031859 19104600.0 64581.0 59503.0 129684.0 205380.0 153257.0 159394.0 125659.0 159285.0 130856.0 178770.0 True False 85116.41463175195 78736.18110541525 127964.30542597955 158032.8140893688 131979.91095838306 149427.06798252198 136842.40756626095 134671.1632551667 137772.78101218145 172511.31671335327 0.49339612179288117 0.45641168710249985 0.7417733970380996 0.9160721574687062 0.7650507425995846 0.8661870469101552 0.7932372795788222 0.7806511817363136 0.7986303950198598 1.0 17.39633147998392 -5.35860238414879 3.674966305238397 0.831773130866337 0.47201800163115315 0.8140656518003329 0.0695084721160858 0.08643580272891441 2.1305734897362867 0.017520558940146577 0.04105224617371439 4.379228594678126e-06 5.35860238414879 -0.3597551292351838 AHT(ph)FSHPPSSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AHTFSHPPSSTK 12 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 AHT(0.992)FS(0.008)HPPSSTK 93.71600000000001 0.010834 4452600.0 13397.0 19474.0 18657.0 29182.0 64409.0 63368.0 63883.0 57911.0 63782.0 49448.0 True False 15664.847497188746 21407.250020817602 19101.853637066513 27547.02714932049 51788.51881387517 60044.87052701147 57831.53976713213 56390.89761177645 64714.69108631097 58412.53096984734 0.26817614708862675 0.3664838634002705 0.3270163665211995 0.4715944796766351 0.8865994668268783 1.027945023611573 0.9900536547027021 0.9653904166707916 1.1078905503977703 1.0 15.833990276544867 -6.2449951584545325 2.174659724668065 1.0162437722948823 0.3224817086483655 0.9827265182988204 0.04208572333598846 0.036135097810322404 0.33557063289589606 0.013929278937549347 0.01814494511784576 5.688592724917219e-07 6.2449951584545325 -0.6937620636465167 down AHT(ph)FSHPPSSTKR ddPTM_PC-9_AZD4547_30min_R2 1 AHTFSHPPSSTKR 13 1 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 AHT(0.992)FS(0.008)HPPSSTKR 78.40100000000001 0.039522 3325700.0 5363.7 4029.7 11240.0 20577.0 15295.0 10946.0 8316.3 10742.0 7256.6 12660.0 True False 7069.245028109314 5332.221719921539 11090.950255914466 15833.290561480899 13171.553260917697 10261.544889623725 9056.434589192171 9082.070726603271 7640.169061357488 12216.777253404094 0.5786505623763856 0.4364671311688002 0.9078458275748682 1.2960284232954395 1.0781528538754002 0.8399551433881173 0.7413112641198952 0.7434097011200425 0.6253833480698541 1.0 13.576576136577469 -5.267888372440841 23.92455817453978 0.9069684906943131 0.5075588300783347 0.42697113425506983 0.1836872916601421 267.61943624439203 992825.4541230203 0.05451968933220046 0.11825575586751647 5.3964931180749384e-06 5.267888372440841 -0.3994096606159784 AHT(ph)PLNTPDPSTK ddPTM_PC-9_AZD4547_30min_R2 1 AHTPLNTPDPSTK 13 0 Q9BYW2;H7C3H4;A0A1W2PPX9 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 AHT(1)PLNTPDPSTK 185.32 0.00011396 3629500.0 44653.0 40402.0 48390.0 61591.0 60704.0 58044.0 48850.0 57785.0 47374.0 52004.0 True False 58851.725159901776 53461.1563958285 47748.31698253565 47392.14652146424 52276.29742731274 54414.499504231644 53197.555365010565 48855.656017200745 49878.09292406217 50183.355788785666 1.1727339520218616 1.0653164890135807 0.9514771627370092 0.9443797804381753 1.0417058924344549 1.0843136862599272 1.0600637308694782 0.9735430253573911 0.9939170495889453 1.0 15.614921327338442 -4.865413772291504 3.384139223922665 1.0088747039807182 1.1801418839836073 0.580217657791505 0.04321166956320199 0.21651691584698132 4.1526298894564215 0.012430201383001431 0.0848653428515314 1.3632836547225749e-05 4.865413772291504 0.1712671800028891 AHT(ph)PLNTPDPSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AHTPLNTPDPSTK 13 0 Q9BYW2;H7C3H4;A0A1W2PPX9 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 AHT(1)PLNTPDPSTK;AHT(0.993)PLNT(0.007)PDPSTK 139.64 3.5544000000000004e-05 11424000.0 82018.0 110898.0 88522.0 105704.0 124043.0 120763.0 125807.0 112461.0 113495.0 87783.0 True False 95902.02747065965 121907.22054065045 90632.70020155454 99781.74757699172 99737.6646001262 114429.97568888849 113889.65019619597 109509.01791227901 115154.64966355522 103697.36301015456 0.9248260966989919 1.1756057917182783 0.8740116196848645 0.9622399710127691 0.961814859172064 1.1034993790312966 1.0982887789060107 1.0560443846730736 1.1104877339289594 1.0 16.662019681793886 -6.760390216383536 24.998096656506682 1.0787058801380178 0.9837417934734886 0.2607642907629206 0.07872937528298862 40.19424951587096 957696.9800962394 0.026383199614223037 0.024967709570970394 1.736240104799806e-07 6.760390216383536 -0.09496408666452927 AHT(ph)PLNTPDPSTK ddPTM_PC-9_Lapatinib_30min_R1 4 AHTPLNTPDPSTK 13 0 Q9BYW2;H7C3H4;A0A1W2PPX9 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 AHT(1)PLNTPDPSTK;AHT(1)PLNTPDPSTK;AHT(1)PLNTPDPSTK;AHT(1)PLNTPDPSTK 155.14 1.818e-09 35258400.0 315186.0 319632.0 306383.0 275772.0 355513.0 371599.0 329591.0 351437.0 338286.0 311521.0 True False 310691.38984196674 318891.9117421313 281193.3724125819 296053.1928284236 334602.42430545023 355706.5770095773 346655.60927885177 367766.0460038453 300184.66837049543 365366.98977435875 0.8503542972884379 0.8727989136048407 0.7696189866146357 0.8102899307111965 0.915798180104043 0.9735597001503955 0.9487874355943796 1.0065661548432936 0.82159767240024 1.0 18.478986769485623 -6.391368451777456 3.970246063786232 0.9499864783542857 0.825420957033419 0.5428201566905488 0.05396597370160929 0.18398605564584697 4.99524318674073 0.017039140630607283 0.019393699333810355 4.0609865230210796e-07 6.391368451777456 -0.12456552132086673 AHT(ph)PTPGIYMGR ddPTM_PC-9_AZD4547_30min_R2 2 AHTPTPGIYMGR 12 0 Q13595;Q13595-4;Q13595-3;Q13595-2 Q13595 TRA2A Transformer-2 protein homolog alpha 1 AHT(1)PTPGIYMGR;AHT(1)PTPGIYMGR 90.759 0.014205 29515200.0 32749.0 41651.0 40919.0 38952.0 52307.0 49345.0 50823.0 58496.0 47337.0 48322.0 True False 43162.500778483496 55113.871220302295 40376.38732400034 29972.21820240092 45045.07593454217 46259.449349395465 55346.14854280314 49456.78730435535 49839.13717959914 46630.2614880721 0.9256328272901568 1.1819335654894467 0.8658837852395169 0.6427632452815589 0.9660052184366279 0.9920478220185085 1.186914822619224 1.0606156973193528 1.0688153055360383 1.0 15.508978899437146 -6.907919222401807 3.142463602084884 1.0844090210634303 0.9125731670267644 0.25427659769249256 0.13028056243570899 0.38202753352685914 7.561555120293544 0.05403075066148383 0.04644566795220664 1.2361773377020963e-07 6.907919222401807 -0.1718358540366659 AHT(ph)PTPGIYMGR ddPTM_PC-9_Lapatinib_30min_R1 2 AHTPTPGIYMGR 12 0 Q13595;Q13595-4;Q13595-3;Q13595-2 Q13595 TRA2A Transformer-2 protein homolog alpha 1 AHT(0.997)PT(0.003)PGIYMGR;AHT(0.892)PT(0.108)PGIYMGR 107.34 0.0038213 36996000.0 17338.9 65437.0 62984.0 60794.0 77072.0 64331.0 76992.0 102340.0 61474.0 56247.0 True False 17091.64410643517 65285.48464693733 57805.69864527089 65264.99356283885 72538.77648938211 61579.71309288544 80978.2690352507 107095.09001053791 54550.150770081695 65969.21900558352 0.25908513643292586 0.9896355547488243 0.8762525844118044 0.9893249389130244 1.0995851941682462 0.9334613024245965 1.2275159575316004 1.6234100027995415 0.8269030858992686 1.0 16.009505404829696 -4.717860153564461 1.1245276635947612 1.1242032802701822 5.86097039420651e-98 0.5181052749902779 0.22452866877534325 1.6332814130651057 1.564596026508957 0.07102599582120463 2.2598626253630734 1.914872430605941e-05 4.717860153564461 -1.1242032802701822 AHT(ph)PTPGIYMGRPTHSGGGGGGGGGGGGGGGGR ddPTM_PC-9_AZD4547_30min_R2 4 AHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGGR 33 1 Q13595;Q13595-4;Q13595-3 Q13595 TRA2A Transformer-2 protein homolog alpha 1 AHT(0.485)PT(0.485)PGIY(0.03)MGRPT(0.001)HSGGGGGGGGGGGGGGGGR;AHT(0.427)PT(0.427)PGIY(0.141)MGRPT(0.003)HS(0.002)GGGGGGGGGGGGGGGGR;AHT(0.404)PT(0.404)PGIY(0.092)MGRPT(0.092)HS(0.008)GGGGGGGGGGGGGGGGR;AHT(0.496)PT(0.496)PGIY(0.007)MGRPT(0.001)HSGGGGGGGGGGGGGGGGR 78.343 3.9464e-08 151008000.0 27965.4 25369.7 43084.899999999994 63104.0 54193.799999999996 45022.399999999994 33902.9 48696.7 35758.4 48645.2 True False 36857.81548354463 33569.95939347684 42513.56607482644 48556.34774708122 46669.92632308086 42207.14221072495 36920.19242138008 41171.743953843 37648.51602177953 46942.1463544465 0.7851753348737398 0.7151347349991165 0.9056587603348782 1.0343870384717042 0.9942009462177083 0.8991310685291442 0.7865041394274229 0.8770741679122878 0.802019484526901 1.0 15.518596187838373 -5.270757595095685 23.57146672683816 0.9102937353508672 0.7501550358321192 0.40722569108646145 0.07825371099325133 290.43776426806363 734698.8551442603 0.022494061993427388 0.0479809060735756 5.360958001374294e-06 5.270757595095685 -0.16013869951874804 AHT(ph)PTPGIYMGRPTHSGGGGGGGGGGGGGGGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 AHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGGR 33 1 Q13595;Q13595-4;Q13595-3 Q13595 TRA2A Transformer-2 protein homolog alpha 1 AHT(0.754)PT(0.198)PGIY(0.047)MGRPTHSGGGGGGGGGGGGGGGGR;AHT(0.499)PT(0.499)PGIY(0.002)MGRPTHSGGGGGGGGGGGGGGGGR;AHT(0.396)PT(0.396)PGIY(0.181)MGRPT(0.02)HS(0.008)GGGGGGGGGGGGGGGGR;AHT(0.733)PT(0.253)PGIY(0.013)MGRPTHS(0.001)GGGGGGGGGGGGGGGGR;AHT(0.337)PT(0.337)PGIY(0.272)MGRPT(0.046)HS(0.008)GGGGGGGGGGGGGGGGR;AHT(0.485)PT(0.485)PGIY(0.028)MGRPT(0.002)HSGGGGGGGGGGGGGGGGR 76.73100000000001 5.0841000000000005e-08 137772700.0 43745.799999999996 39257.33 43691.8 62760.399999999994 68799.0 62597.700000000004 56569.0 72976.1 60076.7 48443.4 True False 51151.0999210659 43154.53827974448 44733.57821407421 59244.13825996212 55318.32982775389 59314.966415047165 51210.3747959065 71060.55469956936 60955.20808354983 57225.804942256604 0.8938467527486882 0.7541097643500051 0.78170290936427 1.0352696361325473 0.9666675704006709 1.0365073322236118 0.8948825594953196 1.2417571892832724 1.0651699551462204 1.0 15.804378230524547 -5.764962001988524 24.781833519267337 1.0358574215048895 0.8043087735820846 0.5683636880415017 0.08958216015692352 57.02925650483703 401208.9048891041 0.025700924992964887 0.03990637355584474 1.7180586998165788e-06 5.764962001988524 -0.23154864792280483 AHT(ph)PTPGIYMGRPTHSGGGGGGGGGGGGGGGGR ddPTM_PC-9_Lapatinib_30min_R1 5 AHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGGR 33 1 Q13595;Q13595-4;Q13595-3 Q13595 TRA2A Transformer-2 protein homolog alpha 1 AHT(0.797)PT(0.202)PGIY(0.001)MGRPTHSGGGGGGGGGGGGGGGGR;AHT(0.498)PT(0.498)PGIY(0.003)MGRPTHSGGGGGGGGGGGGGGGGR;AHT(0.755)PT(0.236)PGIY(0.008)MGRPTHSGGGGGGGGGGGGGGGGR;AHT(0.771)PT(0.228)PGIY(0.001)MGRPTHSGGGGGGGGGGGGGGGGR;AHT(0.529)PT(0.454)PGIY(0.014)MGRPT(0.003)HSGGGGGGGGGGGGGGGGR 86.527 1.4740999999999998e-11 97388800.0 57087.7 37196.4 53956.8 48488.5 48952.6 52565.7 43327.4 45012.7 53478.399999999994 39549.7 True False 56273.618929397955 37110.27402114 49520.680183271186 52054.50604289428 46073.30431251458 50317.58754763158 45570.68076940364 47104.154368940275 47455.09943948234 46385.81294833729 1.2131644430178106 0.8000350034281382 1.067582457559284 1.1222074753949136 0.9932628401668679 1.0847624381116991 0.9824271231412606 1.0154862311328476 1.023052015760422 1.0 15.501396005618789 -7.29536960534256 24.603081610852662 1.006531875836471 1.0375514875241663 0.03484870755250846 0.10024452497852296 2945.225252163787 2135597.085487854 0.04072842276096005 0.027461240855434194 5.065594185222254e-08 7.29536960534256 0.031019611687695292 AHTLLS(ph)PPSANNATFAR ddPTM_PC-9_AZD4547_30min_R2 1 AHTLLSPPSANNATFAR 17 0 C9IZD2;C9J8Z7;C9JLE1;C9JHC7;F8W8R3;A0A087WWF6;P49005 C9IZD2 POLD2 DNA polymerase delta subunit 2 1 AHT(0.002)LLS(0.998)PPSANNATFAR 72.585 0.0066971999999999995 5134300.0 9963.9 8549.8 15701.0 22202.0 15326.0 12366.0 11106.0 15665.0 10143.0 11545.0 True False 13132.212938005181 11313.355649548395 15492.794481148852 17083.671917480624 13198.249446016653 11592.752065145894 12094.412484827168 13244.33419588905 10679.138272655095 11140.813064024509 1.1787481634003198 1.0154874320691238 1.3906340939493542 1.5334313410792764 1.1846756040307274 1.0405660698661905 1.085595137026577 1.188812173741354 0.9585600450598856 1.0 13.443566904923243 -6.532899698947441 9.013274026894372 1.0730194729150722 1.2798712397192196 0.37011672339734036 0.13774853618238148 0.20526632228185945 139.1261261712894 0.04911964118449297 0.05017413780846923 2.9315702182235735e-07 6.532899698947441 0.2068517668041474 AHTLLS(ph)PPSANNATFAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AHTLLSPPSANNATFAR 17 0 C9IZD2;C9J8Z7;C9JLE1;C9JHC7;F8W8R3;A0A087WWF6;P49005 C9IZD2 POLD2 DNA polymerase delta subunit 2 1 AHT(0.001)LLS(0.999)PPSANNATFAR 74.657 0.026476 0.0 15217.0 19578.0 19661.0 22197.0 21021.0 23450.0 20456.0 14222.0 23990.0 15541.0 True False 17792.937550550225 21521.574453505556 20129.792804757715 20953.37405364497 16902.085950511122 22220.24071863431 18518.259591385104 13848.687569454585 24340.808365378936 18358.460277511695 0.969195525201304 1.1722973565418522 1.0964858980802341 1.1413470267608405 0.9206701267434412 1.2103542662481956 1.008704396308723 0.7543490772163839 1.3258632803315948 1.0 14.164157444665667 -7.483920373195012 24.925020477369845 1.0003689492895713 1.0867045767924446 0.03157955302018289 0.1528218342270868 1491.162388635467 954027.2749296532 0.060588472748631515 0.0408401301310624 3.281554540779721e-08 7.483920373195012 0.08633562750287327 AHTLLS(ph)PPSANNATFAR ddPTM_PC-9_Lapatinib_30min_R1 2 AHTLLSPPSANNATFAR 17 0 C9IZD2;C9J8Z7;C9JLE1;C9JHC7;F8W8R3;A0A087WWF6;P49005 C9IZD2 POLD2 DNA polymerase delta subunit 2 1 AHT(0.002)LLS(0.998)PPSANNATFAR;AHT(0.001)LLS(0.999)PPSANNATFAR 113.23 0.00011767 11334200.0 29523.0 25057.0 33366.0 27073.0 24267.0 28041.0 25152.0 22644.0 28680.0 23712.0 True False 29101.99660614486 24998.982055997498 30622.77627648464 29064.038732880505 22839.662770757655 26841.751796763623 26454.247490318816 23696.12290598619 25449.75638621114 27810.587605746052 1.0464358761025239 0.8989016129537789 1.101119354635914 1.0450710047879561 0.8212578279373955 0.9651630586625126 0.9512293614699822 0.8520540177687668 0.9151103438372825 1.0 14.763346607043827 -6.235130114456672 24.993126977710563 0.9141445009502243 1.019614617305485 0.36395303357977005 0.06812892881391078 841.7382694523499 799629.6278371017 0.01988360820167833 0.025660606624855243 5.819288459969891e-07 6.235130114456672 0.10547011635526071 AHTPT(ph)PGIYMGRPTHSGGGGGGGGGGGGGGGGR ddPTM_PC-9_AZD4547_30min_R2 2 AHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGGR 33 1 Q13595;Q13595-4;Q13595-3 Q13595 TRA2A Transformer-2 protein homolog alpha 1 AHT(0.246)PT(0.737)PGIY(0.017)MGRPTHSGGGGGGGGGGGGGGGGR;AHT(0.202)PT(0.619)PGIY(0.155)MGRPT(0.021)HS(0.003)GGGGGGGGGGGGGGGGR 69.149 1.6748e-05 70166000.0 25563.1 22081.2 33335.0 59494.0 43917.0 35888.0 28843.0 43401.0 37706.0 39345.0 True False 33691.63405448874 29218.516078599274 32892.956119297945 45778.577473137215 37819.88261260038 33643.91768671809 31409.971123705203 36694.37270576323 39699.06218167536 37967.54352568594 0.8873798757008221 0.7695656175078132 0.8663440682446333 1.2057292419291472 0.996110864718291 0.8861231083848545 0.8272847860819759 0.9664668634919353 1.0456052326592582 1.0 15.212479040135268 -5.541095014320445 24.999860515253467 0.98192382310492 0.8258431474263693 0.3303836920016209 0.09744540181711725 282.3193590195869 387451.32155346556 0.028583894586414194 0.0495191983627315 2.876768970517016e-06 5.541095014320445 -0.15608067567855066 AHTPT(ph)PGIYMGRPTHSGGGGGGGGGGGGGGGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGGR 33 1 Q13595;Q13595-4;Q13595-3 Q13595 TRA2A Transformer-2 protein homolog alpha 1 AHT(0.067)PT(0.887)PGIY(0.047)MGRPTHSGGGGGGGGGGGGGGGGR;AHT(0.195)PT(0.798)PGIY(0.007)MGRPTHSGGGGGGGGGGGGGGGGR 91.809 4.1148e-12 64925000.0 21751.1 23207.9 31366.9 41862.0 41271.2 36169.0 41553.0 38911.0 37406.9 26413.6 True False 25433.131626192604 25511.826936332178 32114.805855630686 39516.60785843515 33184.40462778811 34272.23396811449 37616.7990223321 37889.627479612376 37953.905145597906 31202.176590057457 0.8151076112522498 0.8176297208849685 1.0292488975228746 1.266469592093363 1.0635285180189094 1.0983924108369831 1.2055825308776267 1.2143264227177621 1.2163864606064656 1.0 14.929359051141924 -5.404255808088221 3.2300193971351177 1.1574216328611455 0.8134371335759244 0.7458255941828384 0.0773253516098862 0.11546856976753887 2.2342442546120758 0.020856777886532025 0.049277963325037456 3.942250272923106e-06 5.404255808088221 -0.3439844992852211 AHTPT(ph)PGIYMGRPTHSGGGGGGGGGGGGGGGGR ddPTM_PC-9_Lapatinib_30min_R1 1 AHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGGR 33 1 Q13595;Q13595-4;Q13595-3 Q13595 TRA2A Transformer-2 protein homolog alpha 1 AHT(0.45)PT(0.536)PGIY(0.013)MGRPTHSGGGGGGGGGGGGGGGGR 72.051 6.7918e-06 27370000.0 8674.9 7085.6 8063.6 8151.0 10848.0 8322.8 6946.2 7952.6 10967.0 5746.0 True False 8551.19433521817 7069.1937285379645 7400.641934396133 8750.4517309389 10209.941967988587 7966.853245394398 7305.840247982367 8322.10682839365 9731.78097237021 6739.188443936271 1.2688759791117414 1.0489681045940513 1.098150318241215 1.2984429510666533 1.5150106059395327 1.1821680476323146 1.0840830923129852 1.2348826416749992 1.4440582947530705 1.0 12.718359152270517 -10.644994631085488 4.44520857901915 0.9999736081837268 1.2348713490474188 0.20180797973574127 0.14359743662048477 4.470591727900844e-05 8.828780327023821e-06 0.14852844465849382 0.03601893295295774 2.2646723041653138e-11 10.644994631085488 0.23489774086369197 AHTVLAAS(ph)CAR ddPTM_PC-9_AZD4547_30min_R2 1 AHTVLAASCAR 11 0 Q8WUY1 Q8WUY1 THEM6 Protein THEM6 1 AHTVLAAS(1)CAR 73.499 0.013933000000000001 5086000.0 4847.4 4571.2 6300.8 10665.0 7858.7 7264.7 7496.2 8517.4 6127.0 5945.0 True False 6388.7723678164475 6048.751005311896 6217.247275130414 8206.349022607461 6767.655156036212 6810.437160574595 8163.347277936377 7201.231540380813 6450.860711481593 5736.867359517169 1.1136343177287866 1.0543647998549814 1.083735579979258 1.4304582114825348 1.1796778157697894 1.1871351965766523 1.422962527518403 1.2552550179558082 1.1244570088900427 1.0 12.486047446894784 -5.589317906495779 24.999999329369725 1.2445798276606852 1.0802550782108855 0.21919206820932968 0.12248695537919092 68.52020905312307 25782.173054582396 0.03211909683302428 0.055631914841129955 2.5744359625762014e-06 5.589317906495779 -0.1643247494497997 AHVDEFK ddPTM_PC-9_Lapatinib_30min_R1 1 AHVDEFK 7 0 A0A087WYS1;E7EUC7;Q16851-2;Q16851 A0A087WYS1 UGP2 UTP--glucose-1-phosphate uridylyltransferase 0 104.45 0.0026219 0.0 13044.0 15563.0 15109.0 15235.0 12837.0 13484.0 12625.0 11324.0 16599.0 13860.0 False True 12857.990168023356 15526.964829687873 13866.796342426613 16355.432722470161 12081.952898513042 12907.32075273923 13278.660725400576 11850.15438029445 14729.445824780985 16255.68253271087 0.7909843306886419 0.9551715099285054 0.853043009084536 1.0061363273771227 0.7432448852394142 0.794018997773005 0.816862700085357 0.7289853475207027 0.9061105736496342 1.0 13.988656511762569 -6.275108219886959 24.958619160080435 0.8153767332346517 0.901730011507179 0.10775123390612962 0.09156141632255133 1329.7713952614597 2428090.9251124584 0.02660297441727187 0.030325052766522833 5.307521720069636e-07 6.275108219886959 0.08635327827252737 AHYEPADR ddPTM_PC-9_Lapatinib_30min_R1 1 AHYEPADR 8 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;H7C3Z6;O95819-6;E7EN19 C9J840;O95819-6;E7EN19 MAP4K4 0 78.77 0.018177000000000002 555050.0 4570.3 3748.9 4276.5 4117.6 5434.2 3621.3 2825.6 3093.4 3392.3 3540.1 False True 4505.12668390963 3740.2196523817297 3924.902677767382 4420.4220399109345 5114.571040048267 3466.425440662605 2971.8957422330177 3237.1306570119073 3010.2234514973507 4152.001568113261 1.0850493695639027 0.9008232754789994 0.9453037561233205 1.064648451450284 1.231832636896718 0.8348805711645737 0.7157742340601998 0.7796554514508321 0.7250053744236052 1.0 12.019591273229942 -6.972142942325746 21.537689173870334 0.7851153670190596 1.0330237670314089 0.5246068325450894 0.1109189529207774 36.170789428657564 27964.715779187634 0.03956032512079639 0.03488670257690356 1.0662451228894621e-07 6.972142942325746 0.24790840001234926 AIADTGANVVVTGGK ddPTM_PC-9_Lapatinib_30min_R1 1 AIADTGANVVVTGGK 15 0 P50990-2;P50990;P50990-3;H7C4C8 P50990-2 CCT8 T-complex protein 1 subunit theta 0 152.16 7.4975e-10 0.0 19545.0 22188.0 24545.0 26370.0 25545.0 25753.0 23396.0 23009.0 16876.0 19695.0 False True 19266.284715885962 22136.625049226655 22527.00484643994 28309.33776774124 24042.49332340232 24651.60422317513 24607.33040249282 24078.082138484195 14975.247167841668 23099.254508062106 0.8340652166571714 0.958326384148048 0.9752264878755097 1.2255520089559908 1.0408341669646093 1.0672034551838556 1.0652867777141624 1.04237485803191 0.6483000203584495 1.0 14.4955586712394 -14.52218481830105 0.006613943968226818 0.2554108913494932 1.6590792842966626 0.0 0.14670969241027013 362169.6390976796 181.40461963585759 21270.966697185944 17408.03751081328 3.0047973093663813e-15 14.52218481830105 1.4036683929471694 AIAELGIYPAVDPLDSTSR ddPTM_PC-9_Lapatinib_30min_R1 1 AIAELGIYPAVDPLDSTSR 19 0 P06576;H0YH81 P06576 ATP5B ATP synthase subunit beta, mitochondrial;ATP synthase subunit beta 0 130.47 5.506900000000001e-06 0.0 5762.9 5304.0 5667.0 3956.8 4322.8 4190.0 5287.6 6589.5 5954.0 4580.6 False True 5680.719989213574 5291.718913876789 5201.0811352526025 4247.796271497859 4068.5414029517965 4010.8034673670545 5561.366055574498 6895.672226152444 5283.397821600456 5372.350606734161 1.0573993406336653 0.9849913569013344 0.9681201983975366 0.790677411517653 0.7573112219913459 0.7465639830616364 1.0351830069696883 1.28354843734674 0.9834424832544987 1.0 12.391337744693846 -7.510693591002469 24.318878016498253 1.1119704192557331 0.8832515517246826 0.3717934729526561 0.12226666694855834 421.22912217636934 840687.0666860262 0.05720696332457242 0.036267116472505224 3.0853640079959974e-08 7.510693591002469 -0.22871886753105053 AIANECQANFISIK ddPTM_PC-9_Lapatinib_30min_R1 2 AIANECQANFISIK 14 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 ; 231.06 2.1719e-20 16821000.0 44681.0 40410.0 46366.0 46683.0 45942.0 41735.0 43118.0 44405.0 33903.0 40410.0 False True 44043.840746508096 40316.433127783006 42553.96645793583 50116.2235499228 43239.78188544723 39950.09133903678 45350.43906200565 46468.21840842236 30084.487125582826 47394.81465705964 0.9292966132519225 0.8506507182168656 0.8978612273483647 1.057419971204757 0.9123314902341643 0.8429211429163393 0.9568649944124327 0.9804494171916915 0.6347632614088433 1.0 15.532441605808815 AICDHVR ddPTM_PC-9_AZD4547_30min_R2 2 AICDHVR 7 0 A0A5K1VW95;P40925;P40925-3;B9A041;P40925-2;B8ZZ51 A0A5K1VW95 MDH1 Malate dehydrogenase, cytoplasmic 0 ; 134.66 0.0033439999999999998 12719700.0 23387.8 28672.0 31129.0 45727.0 39665.0 32521.0 27075.0 41776.0 26868.0 33774.0 False True 30824.633903539558 37939.66328848063 30716.209120672727 35185.34662510749 34158.19941773787 30487.45672898347 29484.62254877505 35320.47911697807 28288.18762789088 32591.582540005526 0.9457851230667589 1.164093926458172 0.9424583504949225 1.0795838643894684 1.0480681438469384 0.9354395936914299 0.9046698641461566 1.0837301034284812 0.8679599277871115 1.0 14.992211785850738 -6.753915713535416 24.98310243427456 0.9602374006610158 1.040339143750686 0.18827720515907875 0.08030291122119862 278.4620926388649 924660.21757917 0.025133134497445815 0.02466826760130295 1.7623180381936942e-07 6.753915713535416 0.08010174308967011 AICDHVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AICDHVR 7 0 A0A5K1VW95;P40925;P40925-3;B9A041;P40925-2;B8ZZ51 A0A5K1VW95 MDH1 Malate dehydrogenase, cytoplasmic 0 ; 119.56 0.0054034999999999994 8339400.0 15259.7 20393.5 18372.2 20282.5 29116.0 26295.4 28323.8 23928.1 25394.7 20071.4 False True 17842.865817186776 22418.031904053823 18810.26292495651 19146.137281752202 23410.92881095485 24916.4229335939 25640.764617445882 23300.0127289176 25766.04944544764 23710.18593488502 0.7525401051762483 0.9455021553023741 0.7933410128716365 0.8075068383830053 0.9873785416634009 1.0508742108569522 1.0814240212144597 0.9827005487391001 1.0867080298825413 1.0 14.533219356004324 -6.384514132627731 3.728125692119528 1.0402334073384452 0.8311799105699166 0.773231153581315 0.055318659882751024 0.11314595598922368 2.806655551444134 0.017257757924994586 0.019721576659456543 4.125588115835557e-07 6.384514132627731 -0.20905349676852858 AICDHVR ddPTM_PC-9_Lapatinib_30min_R1 4 AICDHVR 7 0 A0A5K1VW95;P40925;P40925-3;B9A041;P40925-2;B8ZZ51 A0A5K1VW95 MDH1 Malate dehydrogenase, cytoplasmic 0 ;;; 134.66 0.0033439999999999998 22412200.0 43044.6 42238.2 46783.0 38830.1 44898.5 44031.0 36348.9 41528.1 46397.3 36312.1 False True 42430.77611058714 42140.400043007256 42936.682327602364 41685.795087416336 42257.6585038473 42147.8967712742 38230.86818546637 43457.64713178256 41171.54748877107 42588.59810216812 0.9962942665733591 0.9894761020758265 1.0081731787601744 0.9788017672573771 0.9922293850216222 0.9896521287261746 0.897678484127424 1.0204056735450562 0.9667269955682127 1.0 15.378179620723513 -7.033681123616693 24.996835605548224 0.9687264196961033 0.9926628703679543 0.10431622921754113 0.03026023667298289 1371.8145894436968 1018105.0469890862 0.011222988454132816 0.008699260727984591 9.25377373648946e-08 7.033681123616693 0.023936450671851017 AICGLT(ph)PGRR ddPTM_PC-9_AZD4547_30min_R2 1 AICGLTPGRR 10 1 Q02241;H7BYN4;A0A2U3TZL8;Q02241-2;Q02241-3 Q02241;Q02241-2 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 AICGLT(1)PGRR 65.241 0.041871 7835100.0 32626.0 28492.0 35251.0 57598.0 49656.0 49964.0 31280.0 58711.0 40292.0 49649.0 True False 43000.38933704242 37701.48180857249 34783.54870740579 44319.6709802292 42762.12152495127 46839.7431815421 34063.85940261066 49638.56399456381 42421.752862251706 47910.80362197948 0.8975092481503615 0.786909819047089 0.7260063717956203 0.925045451750619 0.8925360939955886 0.977644698909913 0.7109849309015468 1.0360620202953912 0.8854318787253732 1.0 15.548063391970308 -7.542328897364839 0.23903435050226277 1.021483059380096 0.7789565457709486 0.2097444971860396 0.09391620701097651 3.6831758451448926 0.7982337391271919 0.2539628186246243 0.3451065173618959 2.868607322236761e-08 7.542328897364839 -0.24252651360914745 AICGLT(ph)PGRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AICGLTPGRR 10 1 Q02241;H7BYN4;A0A2U3TZL8;Q02241-2;Q02241-3 Q02241;Q02241-2 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 AICGLT(1)PGRR;AICGLT(1)PGRR 70.685 0.029825 17335400.0 88789.0 85836.0 106235.0 97706.0 118492.0 89783.0 84483.0 90557.0 78729.0 63874.0 True False 103819.22403731367 94357.23080963838 108768.04529848097 92231.84958712611 95274.34320193905 85074.62142606168 76480.15863604765 88179.97470307273 79880.26268436521 75453.85057369426 1.3759300983044664 1.2505290332066163 1.4415174901146948 1.2223610708514487 1.2626836467263722 1.127505366249944 1.013601798378083 1.1686610296574476 1.0586638332837337 1.0 16.203306906037973 -6.608569437716859 1.307887161348146 1.0677085868725142 1.3385522298006594 0.7528624847051034 0.06970549925552928 0.2151964407992095 0.7694684718740746 0.03019241438836719 0.03129667078926084 2.462808037608474e-07 6.608569437716859 0.2708436429281451 AICGLT(ph)PGRR ddPTM_PC-9_Lapatinib_30min_R1 1 AICGLTPGRR 10 1 Q02241;H7BYN4;A0A2U3TZL8;Q02241-2;Q02241-3 Q02241;Q02241-2 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 AICGLT(1)PGRR 64.64 0.043202 8301600.0 40863.0 40055.0 49559.0 41525.0 39757.0 32431.0 30310.0 22768.0 38540.0 22336.0 True False 40280.28612664357 39962.255108471865 45484.45032327227 44578.8870233392 37418.57142526939 31044.001730353455 31879.303492031 23825.884398670434 34199.21935580812 26196.747839150812 1.5376063614447986 1.5254662660358407 1.7362632416263577 1.7016954660576777 1.4283670497964507 1.185032658288922 1.216918362835392 0.9094977951065688 1.3054757623271727 1.0 14.677100100947646 -6.672450324488129 2.169904094296776 1.107085393594435 1.6260576282828028 0.8013181238413389 0.11862395232250209 0.13261530328558954 1.279139926464792 0.044867642593462126 0.04381413161810239 2.1259335000341323e-07 6.672450324488129 0.5189722346883678 AIDGLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AIDGLDR 7 0 A0A0A0MSS8;P42330;S4R3Z2;P42330-2 A0A0A0MSS8;P42330-2 AKR1C3 Aldo-keto reductase family 1 member C3 0 107.32 0.04573 6680900.0 44108.0 45149.0 55254.0 54018.0 56351.0 48567.0 47877.0 40215.0 39254.0 44714.0 False True 51574.61322728978 49631.094340653886 56571.46491196189 50991.546588718906 45309.42606903818 46020.06102268284 43341.74396053699 39159.39886131462 39828.015488728015 52820.29424417073 0.9764166210221666 0.9396216937229803 1.0710176026367961 0.9653779350982384 0.8578033636008862 0.8712571878139743 0.8205509753539513 0.7413703278571999 0.7540286561944598 1.0 15.688804717847782 -6.3733349388956215 1.9624770185449714 0.818226598211803 0.9946512894085047 0.4818586105463091 0.07422178245936015 0.2701760017693628 2.052793768320692 0.02634202904133039 0.031704954097968585 4.233163678291105e-07 6.3733349388956215 0.17642469119670168 AIDGLNR ddPTM_PC-9_Lapatinib_30min_R1 1 AIDGLNR 7 0 B4DK69;P52895;A0A3B3IRI8;Q04828 B4DK69;Q04828 AKR1C2;AKR1C1 Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 107.32 0.04573 51981000.0 58920.0 67437.0 71642.0 75198.0 59974.0 69406.0 60760.0 63194.0 71195.0 58624.0 False True 58079.78999539534 67280.85376981695 65751.87130611732 80728.31177317431 56446.44723342067 66437.66717328831 63905.85549903672 66130.22394103913 63176.26938341363 68757.08028843017 0.8447099520770153 0.9785298254024085 0.9562923706226871 1.1741090726151524 0.8209546856357567 0.9662665560344896 0.9294439966176142 0.9617951149703915 0.9188329277275081 1.0 16.069220662834937 AIDLFTDAIK ddPTM_PC-9_Lapatinib_30min_R1 2 AIDLFTDAIK 10 0 Q3KNR6;Q8NFI4;P50502;H7C3I1;F6VDH7;Q8IZP2 Q3KNR6 ST13;ST13P5;ST13P4 Putative protein FAM10A5;Hsc70-interacting protein;Putative protein FAM10A4 0 ; 152.28 0.00077965 4775700.0 68848.0 63686.0 72774.0 67227.0 64884.0 64112.0 64350.0 56212.0 62957.0 61341.0 False True 67866.2148948231 63538.53897985619 66790.80263576386 72171.09784269772 61067.65068685206 61370.07921237155 67681.72813303181 58823.814731995015 55866.11969339939 71943.71011825535 0.9433238122313962 0.8831701739515045 0.928375844475889 1.003160633835378 0.8488254301380054 0.8530291127813161 0.9407594912992667 0.81763665837229 0.7765254196867399 1.0 16.134580940345934 -6.295038365721684 24.945448614148383 0.8660876739354157 0.934688420588203 0.1979652625896815 0.06465508363877803 992.045856572061 736538.227352911 0.019955443970318554 0.022628302329596367 5.069459225219744e-07 6.295038365721684 0.06860074665278726 AIDS(ph)PGGAVR ddPTM_PC-9_AZD4547_30min_R2 1 AIDSPGGAVR 10 0 O60346 O60346 PHLPP1 PH domain leucine-rich repeat-containing protein phosphatase 1 1 AIDS(1)PGGAVR 90.913 0.008406700000000001 3700500.0 9516.4 12151.0 17315.0 21896.0 16052.0 19025.0 10423.0 18592.0 13844.0 16447.0 True False 12542.41724658342 16078.57312424416 17085.391786579992 16848.21548982775 13823.45687768884 17835.363742471363 11350.626807973495 15719.033601657797 14575.765576913844 15871.19553607718 0.7902629148555924 1.013066286512291 1.0765031372553375 1.0615593167842765 0.8709776680821821 1.1237567895833296 0.7151715056482117 0.9904126986480948 0.9183785521249067 1.0 13.954123186298851 -7.233128475852786 24.999640686630816 0.9051915918390963 0.9922947338399811 0.10774437942878379 0.1173328128757935 1631.4128828653795 1440603.6428704234 0.043703482800575844 0.03384608327456882 5.8461711327781304e-08 7.233128475852786 0.08710314200088487 AIDS(ph)PGGAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AIDSPGGAVR 10 0 O60346 O60346 PHLPP1 PH domain leucine-rich repeat-containing protein phosphatase 1 1 AIDS(1)PGGAVR;AIDS(1)PGGAVR 79.23 0.01931 5557200.0 29053.0 28998.0 32502.0 37332.0 39158.0 34832.0 35719.0 34227.0 31407.0 26197.0 True False 33971.09907709375 31876.72979889436 33276.970944521425 35240.409071977 31485.270998055003 33005.34860176847 32335.437736834385 33328.57751650418 31866.267958793516 30946.30872466211 1.0977431712242012 1.0300656560532135 1.0753130927696697 1.1387596945897713 1.017416043967899 1.0665358797854119 1.044888358884148 1.0769807091707697 1.0297275918209354 1.0 14.917479714603923 -9.139734877536245 0.347244653254732 0.9884886284603783 1.0769363770431744 0.31840942558488095 0.03260432418067951 4.177458553180028 0.9267542410659823 0.10984448572590456 0.03167897523040257 7.248783393612805e-10 9.139734877536245 0.08844774858279603 AIDS(ph)PGGAVR ddPTM_PC-9_Lapatinib_30min_R1 1 AIDSPGGAVR 10 0 O60346 O60346 PHLPP1 PH domain leucine-rich repeat-containing protein phosphatase 1 1 AIDS(1)PGGAVR 73.632 0.02745 2161300.0 19993.0 22822.0 24244.0 21691.0 30626.0 25630.0 25325.0 26413.0 28433.0 21052.0 True False 19707.896153732836 22769.15706117949 22250.75190454634 23286.228499054803 28824.638893032683 24533.86464644812 26636.204583823313 27640.244405397145 25230.576127236443 24690.81014997326 0.798187505149732 0.9221713229690905 0.9011754482495359 0.943113180880378 1.1674237790477646 0.9936435660647892 1.078790222841358 1.1194547379170172 1.0218610071514307 1.0 14.591686554230767 -6.04785040140954 4.971924390452967 1.0669174250591325 0.8838262444058267 0.6849471201274874 0.05847203989129309 0.11472325569112361 6.437510192549884 0.016740402465593014 0.02256635835304415 8.956732391423724e-07 6.04785040140954 -0.18309118065330576 AIEINPDSAQPYK ddPTM_PC-9_Lapatinib_30min_R1 2 AIEINPDSAQPYK 13 0 Q3KNR6;Q8NFI4;P50502;H7C3I1;F6VDH7;Q8IZP2 Q3KNR6 ST13;ST13P5;ST13P4 Putative protein FAM10A5;Hsc70-interacting protein;Putative protein FAM10A4 0 ; 146.36 4.4343999999999994e-05 3488100.0 29077.0 30662.0 32416.0 32256.0 28518.0 28281.0 30139.0 25311.0 27007.0 30470.0 False True 28662.356647931247 30591.004022867655 29750.88160937857 34628.21384286163 26840.62730854522 27071.487556230943 31699.449948740432 26487.04146234837 23965.18726368214 35736.6989012771 0.8020426488498902 0.8560109065298822 0.832502232272925 0.9689818843794815 0.7510662185864636 0.7575262514038057 0.8870279271264087 0.7411720241849707 0.6706043926968785 1.0 15.125118754311842 -6.323712490128137 24.999973459396394 0.7903958409581413 0.8619397051837604 0.09204869034056107 0.09413783936801483 494.8940289864464 198677.2011050816 0.028388451185364136 0.03218948113709106 4.745560449610895e-07 6.323712490128137 0.07154386422561909 AIEPPPLDAVIEAEHTLR ddPTM_PC-9_AZD4547_30min_R2 2 AIEPPPLDAVIEAEHTLR 18 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 0 ; 122.5 4.7891000000000006e-05 2292420.0 12017.599999999999 12102.8 17834.0 22597.8 17701.3 15892.0 17151.199999999997 18950.0 12168.0 16269.0 False True 15838.946818391509 16014.793416846522 17597.50950747141 17388.226342529655 15243.780041679138 14898.270727745316 18677.623573723 16021.712927679382 12811.175638535666 15699.427261898196 1.0088869201510249 1.020087749042521 1.1209013688148852 1.1075707446175505 0.9709768252931816 0.9489690597760052 1.1897009529164644 1.0205284982951803 0.8160282171329787 1.0 13.93842430799813 -8.02217268907531 23.821142384082503 0.9114354163551671 1.0528577054047397 0.33695804505279203 0.07987513977167418 484.6106397576642 520634.37100355775 0.052970512318626956 0.02043198453250406 9.502268785858022e-09 8.02217268907531 0.14142228904957255 AIEPPPLDAVIEAEHTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AIEPPPLDAVIEAEHTLR 18 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 0 ;; 195.28 1.4635e-14 3085440.0 27101.1 28584.9 29761.8 34440.2 36709.8 32692.4 34301.7 34900.9 32519.8 27797.6 False True 31688.780958876032 31422.619960977147 30471.434184255028 32510.627250634927 29516.778213504258 30977.952992319002 31052.39465319781 33984.78835556023 32995.34055358273 32837.08483431946 0.9650302735082231 0.9569247733019225 0.9279579578394247 0.9900582653627238 0.8988854632630177 0.943383164145637 0.9456501638276857 1.0349514436811778 1.0048194204833272 1.0 15.003038434748332 -7.751298210453383 24.987263495173508 1.0149140734375168 0.9461876742459708 0.6188290437555224 0.02387208236338347 120.61091810208427 297180.24659636436 0.011112866657612755 0.006323002479434562 1.7729716430756e-08 7.751298210453383 -0.068726399191546 AIEPPPLDAVIEAEHTLR ddPTM_PC-9_Lapatinib_30min_R1 4 AIEPPPLDAVIEAEHTLR 18 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 0 ;;; 225.37 5.7866e-35 8069800.0 64707.6 69997.0 76740.0 71984.0 73845.1 84956.0 71150.5 57841.5 74311.0 61786.8 False True 63784.857758079466 69834.92624710286 70430.73342496635 77277.94349158448 69501.67640305257 81322.62992210883 74834.32474792983 60529.027250777195 65941.31265047894 72466.56605426405 0.8801970512900584 0.9636847728483425 0.9719065944455925 1.0663944450426641 0.9590861025622308 1.1222089626989253 1.0326738083862392 0.8352683250569946 0.9099549798054608 1.0 16.14502791104801 -4.715238220450951 2.123506992738087 0.9893319987799237 0.8378387789553297 0.15331834304955116 0.07537480453977721 1.8153865214337708 8.006471677258965 0.021828020234382045 0.565197528303446 1.9264679116356213e-05 4.715238220450951 -0.15149321982459407 AIEPQKEEADENYNS(ph)VNTR ddPTM_PC-9_AZD4547_30min_R2 1 AIEPQKEEADENYNSVNTR 19 1 Q12846-2;C9JFM5;Q12846 Q12846-2 STX4 Syntaxin-4 1 AIEPQKEEADENYNS(0.999)VNT(0.001)R 107.06 9.8925e-05 19088000.0 18452.0 31792.0 27455.0 30453.0 31775.0 21869.0 30721.0 37561.0 32838.0 27026.0 True False 24319.352174557305 42068.142273555255 27090.928761221683 23432.531344159856 27363.58972642432 20501.527972883356 33455.109485537134 31756.810515913752 34573.7496398943 26079.82796607418 0.9324966486049302 1.613052905420979 1.038769458006502 0.8984925581043691 1.0492243185814 0.7861067181713266 1.2827964022253926 1.2176771471508343 1.325689329119402 1.0 14.670646732503783 -10.54668789387339 15.138080771865177 0.9999999850905187 1.127030469524006 0.026801044603489643 0.22984968753480844 0.0 0.0 0.22774743910975717 0.05523686749490915 2.8399592345569943e-11 10.54668789387339 0.1270304844334874 AIEPQKEEADENYNS(ph)VNTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AIEPQKEEADENYNSVNTR 19 1 Q12846-2;C9JFM5;Q12846 Q12846-2 STX4 Syntaxin-4 1 AIEPQKEEADENY(0.024)NS(0.966)VNT(0.009)R;AIEPQKEEADENYNS(0.999)VNT(0.001)R;AIEPQKEEADENYNS(0.972)VNT(0.028)R 105.95 0.00010886 25768000.0 35567.5 36142.1 39425.7 32488.9 55114.9 30293.0 34541.5 34845.1 29274.4 26810.8 True False 41588.37525985375 39730.04883318227 40365.75821079989 30668.65226343498 44315.530990620115 28704.3817522213 31269.479061196147 33930.453046435236 29702.482718276322 31671.38580582398 1.3131214249616496 1.2544461766455575 1.2745182183779633 0.968339448468194 1.399229299984437 0.9063190959879917 0.9873100991825269 1.071328335755862 0.9378333774335318 1.0 14.950892374526822 -6.071211985304004 0.5305394992539667 0.9701147213756852 1.3472743742147184 0.4486111189408709 0.12703359097777703 1.268081701525413 0.656599943121782 0.09441388709795612 0.2555752746451635 8.487660791317845e-07 6.071211985304004 0.3771596528390332 AIEPQKEEADENYNS(ph)VNTR ddPTM_PC-9_Lapatinib_30min_R1 3 AIEPQKEEADENYNSVNTR 19 1 Q12846-2;C9JFM5;Q12846 Q12846-2 STX4 Syntaxin-4 1 AIEPQKEEADENYNS(0.996)VNT(0.004)R;AIEPQKEEADENYNS(0.999)VNT(0.001)R;AIEPQKEEADENYNS(0.993)VNT(0.007)R 108.13 8.9325e-05 42091000.0 121467.0 113130.0 65489.0 42598.8 53284.1 32139.0 33230.8 33937.2 65374.0 23779.600000000002 True False 119734.8583056804 112868.05443568657 60104.74721485052 45731.65785743104 50150.033998571234 30764.489889668224 34951.32822444682 35514.046205839695 58010.89170126101 27889.87217567471 4.293130407751099 4.04691902941488 2.1550743164492996 1.6397227484361785 1.7981449926583613 1.1030703079557578 1.2531906924597183 1.2733671198685061 2.0799984788692427 1.0 14.767453701798686 -5.32456378304322 1.9679659330018981 1.4353142435375057 4.428987706052199 0.9232250574632719 0.3097661110044595 0.08980885017001017 0.6372557149513511 0.08881501634137029 0.31852264930185736 4.736267434558134e-06 5.32456378304322 2.9936734625146935 AIEQADLLQEEDES(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AIEQADLLQEEDESPR 16 0 A0A2R8YGH5;H7C1E4;P61966 A0A2R8YGH5 AP1S1 AP-1 complex subunit sigma-1A 1 AIEQADLLQEEDES(1)PR 120.82 0.00096059 0.0 3642.2 5110.9 3979.8 3482.9 4934.7 3398.3 4792.7 3411.3 3417.4 4252.9 True False 4258.752523270949 5618.27637523861 4074.6935254755517 3287.7644047141525 3967.78095904035 3220.087165634755 4338.700759856832 3321.7569895711176 3467.37300991438 5023.917104062123 0.8476956197839142 1.1183059471056784 0.8110590682678521 0.6544225027231854 0.7897783496133273 0.6409514924183624 0.8636091460085488 0.6611886543440949 0.6901732130712928 1.0 12.294596944244903 -5.46477748709063 7.061816488994629 0.743056783486582 0.9806779149671359 0.3461061206956111 0.12131994038246452 0.23401562272831966 24.15281819233353 0.029240305842039745 0.06073780738772359 3.4294345030148176e-06 5.46477748709063 0.23762113148055386 AIGALAS(ph)SR ddPTM_PC-9_AZD4547_30min_R2 1 AIGALASSR 9 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 AIGALAS(0.786)S(0.214)R 70.816 0.036653 13312000.0 49052.0 48168.0 56964.0 72841.0 54383.0 52811.0 50658.0 63096.0 54900.0 58139.0 True False 64649.515655017654 63737.36402342129 56208.620140383566 56048.63283223163 46832.85916891057 49508.71982147985 55166.46386245049 53345.96300183951 57801.90191942867 56103.571306134305 1.152324426946934 1.1360660745754043 1.0018724090428406 0.999020766902647 0.8347571835197933 0.8824521981199905 0.9832968308101029 0.9508479007646831 1.0302713459010882 1.0 15.775804988915771 -5.364754409416855 1.8721781762186456 0.9445007501819719 1.1610186153398645 0.6488708166518096 0.05507013921271655 0.24138624756613167 1.5553649008092967 0.017015530038545244 0.05929759738931644 4.317631669473182e-06 5.364754409416855 0.21651786515789262 AIGALASS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 AIGALASSR 9 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 AIGALAS(0.031)S(0.969)R 81.525 0.017105000000000002 12987000.0 54960.0 44228.0 58189.0 73587.0 58352.0 52081.0 57061.0 64681.0 53791.0 53838.0 True False 72436.13676098369 58523.83607432069 57417.37583998281 56622.65405781676 50250.832028837525 48824.36683688044 62139.31845819584 54686.03767151612 56634.28244349702 51953.14800701181 1.3942588570611238 1.126473338370604 1.1051760681033904 1.0898791744087333 0.9672336317725244 0.9397768703118992 1.1960645474227907 1.0526029657362719 1.0901029988760915 1.0 15.66492354882343 -3.3341760518564922 1.0765892074695222 1.0502732976471578 7.979262479862519 0.6867032985055046 0.0690402284326673 20.14328374287897 1.4505979227489336 0.022221378912732306 304.23360856530826 0.00046325908830197125 3.3341760518564922 6.928989182215361 AIGALASS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 3 AIGALASSR 9 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 AIGALAS(0.053)S(0.947)R;AIGALAS(0.051)S(0.949)R;AIGALAS(0.053)S(0.947)R 86.882 0.01132 36505100.0 250804.0 209998.0 243365.0 195805.0 170297.0 148895.0 123747.0 122969.0 152371.0 126084.0 True False 247227.4889681788 209511.7625332383 223356.46911606682 210205.1528863322 160280.46527678389 142527.1079411977 130154.01416127889 128682.58866040522 135209.37344223761 147877.4514036303 1.6718403422667423 1.4167931658585167 1.5104160032242995 1.4214821184101891 1.083873597735328 0.9638190717269743 0.8801478043195685 0.8701975009642758 0.9143339444847798 1.0 17.17404255913744 -6.325469240017564 1.657826674509551 0.9059576683435642 1.5333141483992343 0.9445596030348619 0.06700660088547189 0.07567654144883383 0.4129749090757442 0.023865022526068865 0.030476006953203984 4.7264031163366936e-07 6.325469240017564 0.6273564800556701 AIGDHFYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AIGDHFYK 8 0 O15355 O15355 PPM1G Protein phosphatase 1G 0 64.265 0.040404 0.0 35437.0 35563.0 37876.0 45737.0 48791.0 39923.0 42995.0 40633.0 37665.0 31471.0 False True 41435.78418734626 39093.45961232085 38779.10748552989 43174.504171354674 39230.75379912412 37829.36759957519 38922.202343156154 39566.42680422224 38215.77936982068 37176.443175701075 1.1145709661226852 1.051565353564344 1.0431096730328502 1.1613403672671407 1.0552583961223532 1.0175628534657903 1.046958746408428 1.064287581714737 1.0279568486207127 1.0 15.182101127799278 -6.512789182097185 24.858702435248485 1.0363536421637594 1.08893955448754 0.40462986570226533 0.03469007967345735 536.728609920089 1322397.4543340784 0.011202884031065695 0.011890001819463104 3.070512133599508e-07 6.512789182097185 0.052585912323780626 AIGDHFYK ddPTM_PC-9_Lapatinib_30min_R1 2 AIGDHFYK 8 0 O15355 O15355 PPM1G Protein phosphatase 1G 0 ; 84.476 0.011706 2274300.0 105440.0 111467.0 105716.0 98560.0 113653.0 110902.0 105054.0 99591.0 107283.0 100280.0 False True 103936.40626467194 111208.90501001192 97024.43855556127 105808.43118652182 106968.15399039506 106158.97998518893 110493.1820868303 104218.36143482037 95199.65879992639 117613.2643852991 0.8837133023038796 0.9455473036246438 0.8249446953339448 0.8996300862791731 0.9094905625607769 0.9026106072306085 0.9394619107319092 0.886110609883276 0.809429610660698 1.0 16.843691250459294 -5.978497540934508 24.95408329984728 0.9035733801941709 0.8860615258134421 0.03403764440561852 0.05202821944195364 1216.6025785754864 1411883.4453234298 0.014406902661311548 0.02136736973416417 1.0507574044552112e-06 5.978497540934508 -0.017511854380728775 AIGGIILT(ph)ASHNPGGPNGDFGIK ddPTM_PC-9_AZD4547_30min_R2 1 AIGGIILTASHNPGGPNGDFGIK 23 0 A0A3B3ITK7;P36871;P36871-2 A0A3B3ITK7 PGM1 Phosphoglucomutase-1 1 AIGGIILT(0.5)AS(0.5)HNPGGPNGDFGIK 99.881 1.2612e-05 5441100.0 17665.0 25043.0 26491.0 30859.0 33269.0 27940.0 28396.0 34019.0 27524.0 31662.0 True False 23282.102545174228 33137.66000744351 26139.7120310881 23744.93431679735 28650.17361474147 26192.907383161608 30923.188989658946 28762.145228850924 28978.862448640317 30553.523017162748 0.762010408164585 1.0845773820855023 0.855538394587253 0.777158637433044 0.9377044211447526 0.8572794491963607 1.0120989639161593 0.9413691904758231 0.9484622258572963 1.0 14.899051121176038 -7.2559093002375485 24.948603239067957 0.9705966946174218 0.8853538589964206 0.2267913234681198 0.08657870332566842 790.0151225614147 3564110.780491782 0.033384145186115176 0.025113395005783492 5.54741555262529e-08 7.2559093002375485 -0.08524283562100121 AIGGIILT(ph)ASHNPGGPNGDFGIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AIGGIILTASHNPGGPNGDFGIK 23 0 A0A3B3ITK7;P36871;P36871-2 A0A3B3ITK7 PGM1 Phosphoglucomutase-1 1 AIGGIILT(0.78)AS(0.22)HNPGGPNGDFGIK 68.074 0.0028708 1927500.0 3132.6 4855.9 5025.3 4130.6 3973.6 3784.7 5118.1 4954.8 2536.9 4055.0 True False 3662.887308329739 5337.961660474899 5145.122210556382 3899.1758735858834 3195.001604726272 3586.2236694164308 4633.276516164847 4824.741750044551 2573.997363156725 4790.13940063766 0.7646723825703564 1.114364575645609 1.074106989427378 0.8140005013354784 0.6669955376039693 0.7486679132843264 0.9672529604353618 1.0072236623014112 0.5373533310563104 1.0 12.225851925943433 -5.776631027569288 24.755019513258034 0.8172758646888602 0.9973796255905347 0.17114922015355827 0.16472559941530587 334.5259623358203 545114.2630756608 0.04655465537147268 0.06935880592938186 1.672510960156053e-06 5.776631027569288 0.18010376090167457 AIGGIILT(ph)ASHNPGGPNGDFGIK ddPTM_PC-9_Lapatinib_30min_R1 3 AIGGIILTASHNPGGPNGDFGIK 23 0 A0A3B3ITK7;P36871;P36871-2 A0A3B3ITK7 PGM1 Phosphoglucomutase-1 1 AIGGIILT(0.5)AS(0.5)HNPGGPNGDFGIK;AIGGIILT(0.722)AS(0.278)HNPGGPNGDFGIK;AIGGIILT(0.676)AS(0.324)HNPGGPNGDFGIK 71.678 0.0016974 8956410.0 29447.5 33263.2 34484.7 29011.399999999998 36476.5 38102.200000000004 28221.4 29137.7 34346.1 28299.5 True False 29027.57324998989 33186.18110408492 31649.50108079153 31144.99513519333 34331.02398555824 36472.65772656634 29682.566003629283 30491.543914403537 30477.68053753298 33191.03086828652 0.8745607620679614 0.9998538832909154 0.9535558327907225 0.9383557642059216 1.0343464209290638 1.098870892901834 0.8942947907047527 0.9186681798285964 0.9182504953967517 1.0 15.01850581780775 -10.72954294582887 3.3992313686253053 1.0000732540657975 0.962653436422761 0.032033910119245945 0.06487807317576831 49229316.29623879 67560160.6018876 38110.65714734576 0.017021447839632806 1.8640478401107674e-11 10.72954294582887 -0.03741981764303648 AIGGIILTAS(ph)HNPGGPNGDFGIK ddPTM_PC-9_AZD4547_30min_R2 7 AIGGIILTASHNPGGPNGDFGIK 23 0 A0A3B3ITK7;P36871;P36871-2 A0A3B3ITK7 PGM1 Phosphoglucomutase-1 1 AIGGIILT(0.149)AS(0.851)HNPGGPNGDFGIK;AIGGIILT(0.192)AS(0.808)HNPGGPNGDFGIK;AIGGIILT(0.004)AS(0.996)HNPGGPNGDFGIK;AIGGIILT(0.019)AS(0.981)HNPGGPNGDFGIK;AIGGIILT(0.002)AS(0.998)HNPGGPNGDFGIK;AIGGIILT(0.034)AS(0.966)HNPGGPNGDFGIK;AIGGIILT(0.126)AS(0.874)HNPGGPNGDFGIK 134.69 8.9537e-09 1672377200.0 549714.6 675687.2000000001 685173.2000000001 897574.9 805575.0 690828.9 607802.9 767550.3 682737.7000000001 733674.9 True False 724512.4080260077 894089.8736166385 676087.3556837838 690652.8741989677 693734.8164866808 647631.259674711 661896.1806297634 648943.0376862383 718825.8209853612 707989.165064258 1.0233382709469148 1.2628581307956734 0.9549402576272776 0.9755133387334863 0.9798664311814949 0.9147474165313408 0.9348959183149206 0.916600238687748 1.015306245428374 1.0 19.433367756174924 -5.287584576313408 24.762060260096288 0.9570440120666978 1.1430981900229802 0.5761595173447499 0.06221433467129794 356.1279958256937 337287.5016505861 0.015079690878046698 0.03140628685336044 5.157217214995631e-06 5.287584576313408 0.18605417795628243 AIGGIILTAS(ph)HNPGGPNGDFGIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 10 AIGGIILTASHNPGGPNGDFGIK 23 0 A0A3B3ITK7;P36871;P36871-2 A0A3B3ITK7 PGM1 Phosphoglucomutase-1 1 AIGGIILT(0.208)AS(0.792)HNPGGPNGDFGIK;AIGGIILT(0.011)AS(0.989)HNPGGPNGDFGIK;AIGGIILT(0.015)AS(0.985)HNPGGPNGDFGIK;AIGGIILT(0.189)AS(0.811)HNPGGPNGDFGIK;AIGGIILT(0.009)AS(0.991)HNPGGPNGDFGIK;AIGGIILT(0.458)AS(0.542)HNPGGPNGDFGIK;AIGGIILT(0.077)AS(0.923)HNPGGPNGDFGIK;AIGGIILT(0.035)AS(0.965)HNPGGPNGDFGIK;AIGGIILT(0.429)AS(0.571)HNPGGPNGDFGIK;AIGGIILT(0.029)AS(0.971)HNPGGPNGDFGIK 131.42 8.5893e-08 1764286900.0 944477.3 1008355.9 846474.7000000001 1066549.3 1088791.1 860957.2000000001 980881.0 924023.5 858975.9 826556.1 True False 1104358.6526130193 1108458.8097600185 866657.8671211777 1006794.0005204862 875450.2999073113 815807.0888034708 887964.8507165317 899768.8622088241 871536.7975147528 976404.1779155129 1.1310466276073003 1.1352458693145127 0.8876015555068308 1.0311242242632055 0.8966064665723532 0.8355219152637235 0.9094234445127152 0.9215127122148385 0.8925983903257795 1.0 19.897118942686866 -5.256741249273512 24.932236178785114 0.9184769584944701 1.1331462779119372 0.7152436598907146 0.053308782910966676 191.2937381098385 1015156.2604858651 0.013938094762665285 0.03440778379707773 5.536798909885424e-06 5.256741249273512 0.21466931941746714 AIGGIILTAS(ph)HNPGGPNGDFGIK ddPTM_PC-9_Lapatinib_30min_R1 8 AIGGIILTASHNPGGPNGDFGIK 23 0 A0A3B3ITK7;P36871;P36871-2 A0A3B3ITK7 PGM1 Phosphoglucomutase-1 1 AIGGIILT(0.142)AS(0.858)HNPGGPNGDFGIK;AIGGIILT(0.088)AS(0.912)HNPGGPNGDFGIK;AIGGIILT(0.233)AS(0.767)HNPGGPNGDFGIK;AIGGIILT(0.032)AS(0.968)HNPGGPNGDFGIK;AIGGIILT(0.24)AS(0.76)HNPGGPNGDFGIK;AIGGIILT(0.217)AS(0.783)HNPGGPNGDFGIK;AIGGIILT(0.165)AS(0.835)HNPGGPNGDFGIK;AIGGIILT(0.484)AS(0.516)HNPGGPNGDFGIK 132.94 1.4214e-08 1062837100.0 795656.0 871778.0 1063249.0 849998.0 982691.0 916856.0 917091.0 914348.6 888174.0 812752.2 True False 784309.7995345596 869759.4516028791 975832.7714798318 912509.6884302073 924891.0474248406 877644.2061757256 964573.4846192744 956832.5739496734 788138.4912331481 953235.3348457679 0.8227871658381818 0.9124288827832897 1.0237060417380772 0.9572763986742582 0.9702651733682183 0.920700454644526 1.0118943867889045 1.0037737156527957 0.8268036888924892 1.0 19.862472905257825 -4.883335326101214 3.487311733487032 0.9648291665763755 0.8192360145123504 0.38617421833462484 0.054559901475675965 0.2555987534497382 5.311289151254795 0.01337540099902678 0.08369814866654825 1.3081714716785796e-05 4.883335326101214 -0.14559315206402512 AIGGIILTASHNPGGPNGDFGIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AIGGIILTASHNPGGPNGDFGIK 23 0 A0A3B3ITK7;P36871;P36871-2 A0A3B3ITK7 PGM1 Phosphoglucomutase-1 0 141.31 1.4557e-11 0.0 6049.5 6283.4 6341.6 7784.3 6770.8 6344.9 7182.8 6443.9 4264.4 5799.5 False True 7073.560866928667 6907.174426456062 6492.807794651928 7348.170908041105 5444.110344594486 6012.162274441914 6502.393185031328 6274.7544528764165 4326.758782547811 6850.903441183259 1.032500447226702 1.0082136590824704 0.9477301571091065 1.0725842177060314 0.7946558277070392 0.8775721809623869 0.9491292996399702 0.9159017502942163 0.6315603218895334 1.0 12.742078536117853 -6.260227103995415 24.9999490293752 0.8624530682021758 1.0099306622326514 0.37172996620954335 0.09784269425573108 127.32029638293645 2625641.2464985717 0.029093334194315094 0.03548344127200411 5.492535796192257e-07 6.260227103995415 0.14747759403047556 AIGNNSAT(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 AIGNNSATSPR 11 0 A0A1B0GV57;Q9NYJ8;Q9NYJ8-2 A0A1B0GV57 TAB2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 1 AIGNNS(0.018)AT(0.491)S(0.491)PR 96.06700000000001 0.014568000000000001 30712000.0 34254.0 32329.0 27699.0 25866.0 38711.0 34174.0 41991.0 34473.0 45299.0 46156.0 True False 33765.53167858573 32254.144186787857 25421.695141232038 27768.27192644652 36434.095088754264 32712.457683484925 44165.08851645902 36074.74142987377 40196.94960038279 54134.00310099588 0.623739789122755 0.5958204148806888 0.46960678473756484 0.5129543417404445 0.6730353013203267 0.6042866924593487 0.8158474523685565 0.6663970769457122 0.7425453005089754 1.0 15.724247455952558 -8.669301847401412 0.3246601448482876 1.048576901322632 0.5258398645693776 0.762468885784245 0.07100192522573728 1.0587246011102212 0.2942956098845317 0.18779195786144237 0.09199832876273546 2.141401746766702e-09 8.669301847401412 -0.5227370367532544 AIGNNSATS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 AIGNNSATSPR 11 0 A0A1B0GV57;Q9NYJ8;Q9NYJ8-2 A0A1B0GV57 TAB2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 1 AIGNNS(0.001)AT(0.144)S(0.856)PR;AIGNNS(0.012)AT(0.235)S(0.753)PR 105.2 0.0025875 78990000.0 44146.0 50643.0 83267.0 148884.0 93966.0 79650.0 105287.0 189328.0 124925.0 123246.0 True False 58183.50970615689 67012.35937215835 82162.82517430867 114561.09403487007 80920.44287122542 74669.47290869082 114657.33903205486 160071.70792462677 131528.28046055764 118931.19505316293 0.48921991980445945 0.5634548559123066 0.6908433496996429 0.9632552164607494 0.6803971223450123 0.6278375734416285 0.9640644658518934 1.3459186032148571 1.1059191022318724 1.0 16.859767650796215 -7.459763618296461 3.9021367536620866 1.1703498801294658 0.6812178900419664 0.7032733047101637 0.14152533918464727 0.1311568459366959 3.9403781634294406 0.06904257520616064 0.043037962663544184 3.4692562687136206e-08 7.459763618296461 -0.4891319900874994 AIGNNSATS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AIGNNSATSPR 11 0 A0A1B0GV57;Q9NYJ8;Q9NYJ8-2 A0A1B0GV57 TAB2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 1 AIGNNS(0.002)AT(0.1)S(0.898)PR;AIGNNSAT(0.003)S(0.997)PR 130.44 0.00020925 51443000.0 107148.0 113962.0 113780.0 126940.0 178909.0 150525.0 152193.0 213827.0 161884.0 136754.0 True False 125286.04013053553 125275.39421138023 116492.94671305268 119827.96334503256 143853.0657590027 142631.20401588175 137776.1772580991 208214.26781843347 164251.247245561 161546.41765593132 0.7755420513092111 0.7754761512458747 0.721111296699655 0.7417556209772936 0.8904751206887627 0.8829115871802492 0.8528581398291412 1.288881987231047 1.016743358527396 1.0 17.301589233165586 -7.626697767266222 6.778455145340626 1.112966334120905 0.8009871071798432 0.7013893761445987 0.08899088158368457 0.11600836531947524 6.653253347306269 0.04306756518352046 0.024611742924853148 2.3621215008595696e-08 7.626697767266222 -0.31197922694106184 AIGNNSATS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 AIGNNSATSPR 11 0 A0A1B0GV57;Q9NYJ8;Q9NYJ8-2 A0A1B0GV57 TAB2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 1 AIGNNS(0.003)AT(0.216)S(0.781)PR 84.821 0.0118 33048000.0 43595.0 39409.0 43258.0 35978.0 53338.0 45714.0 54004.0 44175.0 58203.0 52972.0 True False 42973.327305656145 39317.75088178176 39701.49422070886 38623.94213908966 50200.76370654269 43758.91878453883 56800.062876398566 46227.53176876609 51647.56523523873 62128.139619246766 0.6916886224023256 0.6328493195312331 0.6390259625351743 0.6216819363302534 0.8080197478018628 0.7043333190518181 0.9142405232878146 0.7440675360967223 0.8313071267184501 1.0 15.922959234050001 -7.815588152704111 0.23250885817426062 1.0502611995469116 0.5610812666413267 0.7145113076891678 0.06471950816474603 1.2053125558106512 0.28965845192122486 0.2107521848469328 0.23239339566784306 1.5290153567538785e-08 7.815588152704111 -0.4891799329055848 AIGSTSKPQES(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AIGSTSKPQESPK 13 1 P18887;F5H8D7;M0QYS5 P18887 XRCC1 DNA repair protein XRCC1 1 AIGSTS(0.001)KPQES(0.999)PK 57.567 0.032494999999999996 24741000.0 27948.0 38076.0 23949.0 34092.0 32445.0 28944.0 35980.0 26887.0 29542.0 30416.0 True False 32679.044401838568 41855.93364448243 24520.034987088267 32181.935767755273 26087.63515838131 27426.125687000058 32571.713927358025 26181.24473913132 29973.995862026874 35930.18002707648 0.9095151868766619 1.1649241282103342 0.6824356284496853 0.8956797807164734 0.7260646937678028 0.7633172354363967 0.9065279913101587 0.7286700127692515 0.8342289362157075 1.0 15.13290854348735 -5.261726005976131 24.999922291319397 0.8082511630159458 1.0372196549665922 0.3939116781038505 0.10876480984118318 21.256893636308234 1854267.2058197097 0.025751403000573533 0.05956329824182243 5.47361181173137e-06 5.261726005976131 0.2289684919506464 AIGSTSKPQES(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 AIGSTSKPQESPK 13 1 P18887;F5H8D7;M0QYS5 P18887 XRCC1 DNA repair protein XRCC1 1 AIGS(0.007)T(0.007)S(0.007)KPQES(0.978)PK 53.49100000000001 0.040783 105910000.0 189100.0 192090.0 102070.0 144800.0 156140.0 133390.0 132710.0 115560.0 110060.0 130760.0 True False 186403.3993233072 191645.22740697456 93678.19860159425 155449.07503863974 146956.152183051 127685.22064727714 139581.07444498292 120929.33947252076 97663.88381682007 153361.69177325192 1.2154495504581944 1.249629064410202 0.6108318023779966 1.0136108518447622 0.9582324665557834 0.8325757180356492 0.9101430274475331 0.7885237706644304 0.6368205950754503 1.0 17.22657863139262 -5.23844696083292 24.68437488540346 0.8484035910634838 1.2325394583072444 0.5844243009427162 0.13106373929926987 466.69624375045987 501037.1241388293 0.03298715030764446 0.08714422680270828 5.775013970334255e-06 5.23844696083292 0.3841358672437606 AIGSTSKPQES(ph)PKGK ddPTM_PC-9_AZD4547_30min_R2 1 AIGSTSKPQESPKGK 15 2 P18887;F5H8D7;M0QYS5 P18887 XRCC1 DNA repair protein XRCC1 1 AIGS(0.013)T(0.013)S(0.013)KPQES(0.961)PKGK 55.196000000000005 0.022813 23141000.0 106420.0 99942.0 90953.0 123860.0 124940.0 91017.0 118770.0 104340.0 87491.0 114970.0 True False 140259.34632648987 132246.29702766915 89746.90379236553 95305.99061792406 107594.23762138316 85325.6926017615 129340.29991202247 88216.65049467378 92115.59564358344 110944.93529414432 1.264224869342844 1.1919994065258526 0.8089319584929477 0.8590386786493923 0.969798552192783 0.7690814580723362 1.165806258475046 0.7951390503837615 0.8302821160728128 1.0 16.759484283541816 -5.172810267027715 5.273217234690054 0.8987117286913077 1.242708808015418 0.5716995265893856 0.11403240042108852 0.149329320980878 6.702323810381289 0.02835254145500753 0.07915915298561721 6.7172224837217985e-06 5.172810267027715 0.3439970793241104 AIHDLGK ddPTM_PC-9_Lapatinib_30min_R1 1 AIHDLGK 7 0 Q9BUP3-3;Q9BUP3;E9PI87 Q9BUP3-3 HTATIP2 Oxidoreductase HTATIP2 0 97.602 0.0050973 0.0 53016.0 47554.0 54164.0 50691.0 53760.0 48817.0 43823.0 46610.0 54623.0 46781.0 False True 52259.98211805633 47443.891634709034 49710.84499908629 54418.9852402189 50597.94249622665 46729.21070798508 46091.94051241419 48775.67075817063 48470.78253431002 54867.033518235716 0.952484192546825 0.8647067025947465 0.906023923866128 0.991833925596362 0.9221920569007949 0.8516810133803584 0.8400662029066139 0.8889795498413351 0.8834226934867943 1.0 15.743651955644758 -6.6382359631422005 8.7382333419133 0.8826837167473149 0.9267996718647168 0.08840561840919314 0.05075369372810942 0.5217015907944372 37.7606545271107 0.016649914086476068 0.0166374540083237 2.3001917256751163e-07 6.6382359631422005 0.04411595511740185 AILDAEPGPRPALQPS(ph)PSIR ddPTM_PC-9_AZD4547_30min_R2 2 AILDAEPGPRPALQPSPSIR 20 1 B5MD46;Q9BXI6;Q9BXI6-2 B5MD46 TBC1D10A TBC1 domain family member 10A 1 AILDAEPGPRPALQPS(0.728)PS(0.272)IR;AILDAEPGPRPALQPS(0.947)PS(0.053)IR 62.916000000000004 0.0043168 36290000.0 68262.0 68845.0 74884.0 88500.0 84843.0 85352.0 73159.0 100420.0 82677.0 93073.0 True False 89967.89606219542 91097.79991264828 73890.98923166352 68097.69231136996 73064.0139467826 80014.92594730167 79670.00927223763 84902.39642203524 87047.13743155915 89814.54259921631 1.0017074457937556 1.014287856691074 0.8227062911336173 0.7582034082748216 0.8134987033538612 0.8908905354487644 0.8870502144374647 0.9453078974181188 0.9691875604153964 1.0 16.454661441855684 -7.982583854631944 1.6769909116053603 0.9916784460281386 0.877769974726371 0.23385960174149667 0.07478620723233663 0.647657811987004 3.286427256282398 0.07447057276802829 0.025013066030219532 1.0409171054195164e-08 7.982583854631944 -0.11390847130176762 AILDAEPGPRPALQPS(ph)PSIR ddPTM_PC-9_Lapatinib_30min_R1 2 AILDAEPGPRPALQPSPSIR 20 1 B5MD46;Q9BXI6;Q9BXI6-2 B5MD46 TBC1D10A TBC1 domain family member 10A 1 AILDAEPGPRPALQPS(0.807)PS(0.193)IR;AILDAEPGPRPALQPS(0.814)PS(0.186)IR 55.093999999999994 0.01095 22406500.0 50733.0 85813.0 72879.0 66150.0 72824.0 68394.0 59758.0 67989.0 79572.0 54095.0 True False 50009.53811670726 85614.30527083519 66887.16994107551 71014.89166993099 68540.63549749262 65468.948054200984 62851.97684186035 71148.01714604712 70609.76342969282 63445.24867294334 0.7882314146880186 1.3494202806607645 1.0542502605021706 1.119309848338821 1.0803115588815124 1.0318967838189066 0.9906490739103054 1.1214081217146947 1.1129243703288507 1.0 15.953224506221883 -6.537247167159389 14.03451135473054 1.0552688460412116 1.0960583324275006 0.0023099366083320083 0.1329335975212705 7.869826386513056 7668.210647113249 0.041585012881853164 0.0417979018083759 2.9023703773885893e-07 6.537247167159389 0.04078948638628899 AILGSYDSELTPAEYS(ph)PQLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AILGSYDSELTPAEYSPQLTR 21 0 C9J9H5;C9JX80;Q9Y6D9-3;Q9Y6D9 C9J9H5 MAD1L1 Mitotic spindle assembly checkpoint protein MAD1 1 AILGSYDSELTPAEY(0.155)S(0.82)PQLT(0.025)R 112.74 7.4959000000000005e-06 3386800.0 6632.9 7398.5 9365.3 7303.3 11005.0 6824.2 7372.0 5601.0 7903.3 6489.6 True False 7755.718964253435 8132.974185016896 9588.604270098038 6894.119778618068 8848.649250053511 6466.3269386824895 6673.670791341954 5453.9796847500465 8018.87081092536 7666.113108354664 1.0116885642870461 1.0608993201722314 1.2507778237250646 0.89929794684411 1.1542549822817119 0.8434948516002684 0.870541654814468 0.711440022820196 1.0460151966954745 1.0 12.904279568954776 -6.770033856697764 24.99975106206223 0.874778523265789 1.0745406147161998 0.3558556079343205 0.12039058803231922 189.63799778170846 551618.5107125757 0.04042596761578261 0.03620171583133441 1.698111266066442e-07 6.770033856697764 0.1997620914504108 AILGSYDSELTPAEYS(ph)PQLTR ddPTM_PC-9_Lapatinib_30min_R1 1 AILGSYDSELTPAEYSPQLTR 21 0 C9J9H5;C9JX80;Q9Y6D9-3;Q9Y6D9 C9J9H5 MAD1L1 Mitotic spindle assembly checkpoint protein MAD1 1 AILGSYDSELTPAEY(0.167)S(0.789)PQLT(0.044)R 113.89 2.191e-06 2103400.0 6457.3 6841.7 8328.4 9694.4 8776.2 4888.0 6963.2 7991.2 9727.9 6199.9 True False 6365.217717876209 6825.858464002797 7643.671100553699 10407.358515570371 8260.001170673067 4678.95163448453 7323.720424800734 8362.500325309871 8632.241462671662 7271.544454152532 0.8753598025851645 0.9387082080072797 1.051175736976848 1.4312445700070062 1.1359349066422968 0.6434605005835506 1.0071753629476068 1.1500308329318307 1.1871262724306226 1.0 12.828046105437082 -5.211266916242666 3.866871411485496 1.0785747730937778 0.8954664886557491 0.11965852965934032 0.1860985041298993 0.5416647321588975 16.885780720325837 0.053486656333147524 0.1551933171761875 6.147989027886371e-06 5.211266916242666 -0.18310828443802873 AILILDNDGDR ddPTM_PC-9_AZD4547_30min_R2 2 AILILDNDGDR 11 0 F8VXB1;F8VUC5;F8W156;F8W651;F8VXR1;F8VYZ4;F8VVA7;P61923-5;P61923;P61923-4 F8VXB1 COPZ1 Coatomer subunit zeta-1 0 ; 125.48 0.0021146999999999997 4990000.0 28708.0 31008.0 36464.0 39972.0 38477.0 33933.0 29960.0 38637.0 34291.0 32216.0 False True 37836.54683650509 41030.72960551085 35980.463534845636 30757.072961243808 33135.13271136516 31811.16414577033 32626.381959789498 32666.53943993398 36103.552253536014 31088.127645787226 1.2170738382062822 1.3198199027296826 1.157369911266476 0.9893510896405406 1.0658452348401664 1.0232576406086997 1.049480442551217 1.0507721729700452 1.1613292593524343 1.0 14.924076109207519 -5.518722017662641 4.582736660974347 1.050889450036232 1.2649430817596234 0.7565584092812412 0.05013194111951028 0.08430154120339094 4.6009166176322 0.013213326584192815 0.025979178198134546 3.0288515089477958e-06 5.518722017662641 0.21405363172339142 AILILDNDGDR ddPTM_PC-9_Lapatinib_30min_R1 2 AILILDNDGDR 11 0 F8VXB1;F8VUC5;F8W156;F8W651;F8VXR1;F8VYZ4;F8VVA7;P61923-5;P61923;P61923-4 F8VXB1 COPZ1 Coatomer subunit zeta-1 0 ; 171.33 0.00037891 7482800.0 29910.0 41704.0 37698.0 35499.0 44986.0 39007.0 38442.0 35091.0 40843.0 34601.0 False True 29483.47791517775 41607.436950286115 34598.615958488226 38109.71488119252 42340.01192587892 37338.761539758176 40432.33866184941 36721.455965993664 36242.83124414301 40581.73674706558 0.7265208509665291 1.0252749213177699 0.852566172170786 0.9390853604595469 1.0433267602560277 0.9200878161642034 0.9963185881829719 0.9048764027736923 0.8930823111399658 1.0 15.30854298793537 -4.749102441995096 24.974830945942035 0.9493786250055517 0.7265203311811707 0.5687906561747261 0.05902429883529868 427.12298828062615 864612.4662297344 0.01434773593909921 0.2435998742968904 1.781958387011749e-05 4.749102441995096 -0.22285829382438105 AILPCIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AILPCIK 7 0 P60842;P60842-2;J3KT12;J3QL43;J3QS69;J3KTB5;J3QR64;J3KS25;J3QLN6;J3QKZ9;J3KT04;J3KS93;J3QQP0 P60842 EIF4A1 Eukaryotic initiation factor 4A-I 0 98.03 0.018737 0.0 32984.0 32171.0 30467.0 42724.0 38427.0 37037.0 31998.0 29058.0 31912.0 32441.0 False True 38567.5397363047 35364.72426926793 31193.448826740914 40330.312793076875 30897.50520052759 35094.71452008782 28966.91779454149 28295.25828949596 32378.652628427375 38322.296497185285 1.0063994922417405 0.9228237214819685 0.8139765013569066 1.052398120139775 0.80625400940669 0.9157779602969638 0.7558763550788002 0.7383497565594537 0.8449037659004996 1.0 15.225896397978111 -6.305095432210551 24.998713505114697 0.8296744596734632 0.9373996970582039 0.2282439065009213 0.0918818727929617 664.3969419748223 380451.02901026804 0.028062531148177403 0.03182009661463994 4.953413321515147e-07 6.305095432210551 0.10772523738474071 AILVDLEPGTMDS(ph)VR ddPTM_PC-9_AZD4547_30min_R2 1 AILVDLEPGTMDSVR 15 0 A0A0B4J269;Q13509;G3V5W4;G3V2R8;G3V3R4;G3V2N6;Q5JP53;P07437;Q9BVA1;Q13885 A0A0B4J269;Q5JP53 TUBB3;TUBB;TUBB2B;TUBB2A Tubulin beta-3 chain;Tubulin beta chain;Tubulin beta-2B chain;Tubulin beta-2A chain 1 AILVDLEPGT(0.202)MDS(0.798)VR 82.55 0.038561 0.0 7623.2 8101.9 8926.8 13656.0 12410.0 8793.3 9110.3 9480.8 8577.0 7594.4 True False 10047.219027589714 10720.680733710284 8808.424799332493 10507.820183096806 10687.08571219278 8243.453560928956 9921.099051010347 8015.7602071104375 9030.362709707462 7328.522367555457 1.3709747372908845 1.4628707119967943 1.201937356202773 1.433825218248171 1.4582865653117498 1.1248452481258768 1.3537652685529955 1.0937757715794787 1.232221484331729 1.0 12.839306625190655 -8.019006749651666 0.4066733126641855 0.9922331300045407 1.4063847538200167 0.5282382660571099 0.10809555266212309 0.836101087522957 0.3943648739413978 0.13196273672073908 0.09676964905575004 9.571791950377828e-09 8.019006749651666 0.414151623815476 AILVDLEPGTMDSVR ddPTM_PC-9_Lapatinib_30min_R1 4 AILVDLEPGTMDSVR 15 0 A0A0B4J269;Q13509;G3V5W4;G3V2R8;G3V3R4;G3V2N6;Q5JP53;P07437;Q9BVA1;Q13885 A0A0B4J269;Q5JP53 TUBB3;TUBB;TUBB2B;TUBB2A Tubulin beta-3 chain;Tubulin beta chain;Tubulin beta-2B chain;Tubulin beta-2A chain 0 ;;; 147.58 0.00036733 95806000.0 365806.0 320707.0 364149.0 319845.0 360522.0 397560.0 331533.0 306343.0 344748.0 287431.0 False True 360589.53935939487 319964.42264567915 334210.0748757892 343367.4682716423 339316.8047735237 380557.28555762477 348698.1565365721 320576.8141401037 305918.8498826192 337113.0653722676 1.0696397630308472 0.9491308866725425 0.9913886740246253 1.0185528344695511 1.0065370928261785 1.1288713628983276 1.0343655952684934 0.9509474626446078 0.9074666078124227 1.0 18.36287301686574 -7.767846751638286 20.36157781886616 0.9469048303439974 1.0265361632151535 0.3264042470117636 0.04947034128632559 18.558836269251945 58962.75917758307 0.027327792882666443 0.013747044575387035 1.7066845160775863e-08 7.767846751638286 0.07963133287115609 AINGPTS(ph)ASGDDISK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AINGPTSASGDDISK 15 0 B4DXZ6;P51114;P51114-3;H7C4S4 B4DXZ6 FXR1 Fragile X mental retardation syndrome-related protein 1 1 AINGPT(0.012)S(0.483)AS(0.483)GDDIS(0.022)K 129.01 0.00026321 0.0 7579.9 4896.2 7337.2 10829.0 8116.6 7452.0 8549.1 9881.7 8718.5 1765.0 True False 8863.027360150856 5382.2623781414795 7512.146674485952 10222.286238091687 6526.2104955006225 7061.204001503753 7739.267357875949 9622.315845526611 8845.991568718477 2084.980528267687 4.250892149824887 2.581444912875685 3.602981693420151 4.902820961395216 3.1301062081970357 3.3867002141121083 3.7119134941303957 4.615062690068067 4.242721430146016 1.0 11.02581819499734 -10.03295007148423 8.285831350654355 1.0000000008569898 3.8001459258031876 0.6182847710949064 0.6656431654752263 0.0 0.0 0.6662764815616975 0.16159578290257512 9.269363821764136e-11 10.03295007148423 2.8001459249461975 AINGPTSAS(ph)GDDISK ddPTM_PC-9_AZD4547_30min_R2 2 AINGPTSASGDDISK 15 0 B4DXZ6;P51114;P51114-3;H7C4S4 B4DXZ6 FXR1 Fragile X mental retardation syndrome-related protein 1 1 AINGPT(0.002)S(0.015)AS(0.982)GDDIS(0.002)K;AINGPTS(0.002)AS(0.541)GDDIS(0.457)K 169.67 0.00017085 24370000.0 50574.0 44458.0 60916.0 79432.0 67447.0 57959.0 63018.0 67324.0 52885.0 71405.0 True False 66655.479995451 58828.17907642554 60108.21403819268 61120.17961216654 58083.14826996506 54334.8145676687 68626.47991795768 56920.622751614166 55680.39313313267 68905.13268399052 0.9673514497264408 0.8537561250512435 0.8723328973743966 0.8870192572224341 0.8429437112666666 0.788545242585287 0.9959559940576447 0.8260723190630929 0.8080732300232476 1.0 16.07232383159281 -10.544431640965012 14.901014398021369 0.9999993966455393 0.8703757713450625 0.27617552656598343 0.062469895980637985 0.0 0.0 0.05901831948757393 0.014314045005512739 2.8547518234838553e-11 10.544431640965012 -0.12962362530047677 AINGPTSAS(ph)GDDISK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AINGPTSASGDDISK 15 0 B4DXZ6;P51114;P51114-3;H7C4S4 B4DXZ6 FXR1 Fragile X mental retardation syndrome-related protein 1 1 AINGPT(0.131)S(0.199)AS(0.668)GDDIS(0.003)K;AINGPT(0.002)S(0.053)AS(0.945)GDDISK;AINGPT(0.001)S(0.064)AS(0.928)GDDIS(0.007)K 163.91 4.4722e-15 12002300.0 79589.2 75885.0 79133.0 98809.0 98188.0 88998.0 97272.0 92995.0 80822.0 66623.9 True False 93062.0796016463 83418.36129350644 81019.83083357372 93273.05207310035 78948.76624845574 84330.78820797511 88057.69197170582 90553.97978634734 82003.86884979816 78702.28567549764 1.1824571396230654 1.0599229816203046 1.0294469866813234 1.1851377793229585 1.0031318095890427 1.0715163795329237 1.1188708334950022 1.150588944261621 1.041950283221932 1.0 16.26411791470815 -8.786247694842283 0.008388304616128809 9.974703877781197e-05 2.1336673045703582 0.15821251430756367 0.06130536301336798 7002.3258397296795 30.124530731704798 3891.875814802811 3766.964053733901 1.6358832481937708e-09 8.786247694842283 2.1335675575315802 AINGPTSAS(ph)GDDISK ddPTM_PC-9_Lapatinib_30min_R1 2 AINGPTSASGDDISK 15 0 B4DXZ6;P51114;P51114-3;H7C4S4 B4DXZ6 FXR1 Fragile X mental retardation syndrome-related protein 1 1 AINGPTS(0.001)AS(0.999)GDDISK;AINGPT(0.005)S(0.082)AS(0.884)GDDIS(0.029)K 208.4 4.654e-13 31040000.0 174975.0 134584.0 152146.0 140829.0 151576.0 136606.0 120840.0 129002.0 145718.0 107064.0 True False 172479.82441351484 134272.37901681633 139637.1431805443 151186.03445177202 142660.59768988175 130763.67982413924 127096.50392533887 134995.9038649545 129305.70436143361 125569.86974618709 1.3735765176960548 1.0693041195966797 1.112027458997857 1.2039992934400792 1.1361053250930335 1.0413619133988936 1.0121576472304825 1.0750660499833293 1.0297510431666268 1.0 16.93813080823272 -1.5228787452803376 0.3618928401490904 1.0325867919492957 4.257715503791995 0.6136830843223662 0.06650147668791005 49.99359289831681 0.6965561260761463 0.05663408535734918 111.25881757280762 0.029999999999999995 1.5228787452803376 3.2251287118426992 AIPGDQHPES(ph)PVHTEPMGIQGR ddPTM_PC-9_AZD4547_30min_R2 5 AIPGDQHPESPVHTEPMGIQGR 22 0 Q14676;Q14676-3 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 AIPGDQHPES(0.754)PVHT(0.246)EPMGIQGR;AIPGDQHPES(1)PVHTEPMGIQGR;AIPGDQHPES(0.889)PVHT(0.111)EPMGIQGR;AIPGDQHPES(0.647)PVHT(0.353)EPMGIQGR;AIPGDQHPES(0.999)PVHT(0.001)EPMGIQGR 103.63 2.7901e-05 67020500.0 140617.0 142480.0 186542.0 257958.0 187150.0 184497.0 167654.0 226922.0 181748.0 179834.0 True False 185330.28098470203 188533.8736517412 184068.33119562262 198489.76851137128 161167.452944148 172960.3734241652 182574.8812111662 191856.4190488056 191354.82823410406 173538.0663972097 1.0679517458751744 1.0864122066463948 1.0606798555327352 1.1437822987899948 0.9287152743493943 0.9966710878769259 1.0520739628000246 1.1055581235396919 1.1026677443559485 1.0 17.404892633947867 -6.188427095803216 24.99999946311376 1.0355607488215588 1.087397712654304 0.2242989925882547 0.0530479893039941 279.73239430682366 95781.3096998454 0.017042476227683494 0.022001741761253565 6.479968641523439e-07 6.188427095803216 0.051836963832745164 AIPGDQHPES(ph)PVHTEPMGIQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AIPGDQHPESPVHTEPMGIQGR 22 0 Q14676;Q14676-3 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 AIPGDQHPES(0.997)PVHT(0.003)EPMGIQGR;AIPGDQHPES(0.938)PVHT(0.062)EPMGIQGR;AIPGDQHPES(0.999)PVHT(0.001)EPMGIQGR;AIPGDQHPES(0.994)PVHT(0.006)EPMGIQGR 70.295 0.0012779999999999998 144749000.0 173963.0 169478.0 180282.0 215048.0 229629.0 210356.0 251854.0 216655.0 225451.0 180324.0 True False 203411.49997413196 186302.65579891828 184580.60660329263 202999.55775502318 184634.84585556938 199324.56104942583 227996.56585494254 210968.03581494777 228747.79436361167 213015.3137560018 0.9549149138034718 0.8745974761810716 0.8665133193884845 0.9529810518108986 0.8667679454588847 0.9357287865122316 1.0703294605199183 0.9903890574580987 1.0738561013769679 1.0 17.700597624539014 -7.1130119476777915 4.733875418096616 1.0321163435125114 0.9021571359933328 0.72146449648953 0.03843260749324185 0.1163158935254697 4.052836360934744 0.014205875567552583 0.010960787748150139 7.708822613817431e-08 7.1130119476777915 -0.12995920751917855 AIPGDQHPES(ph)PVHTEPMGIQGR ddPTM_PC-9_Lapatinib_30min_R1 5 AIPGDQHPESPVHTEPMGIQGR 22 0 Q14676;Q14676-3 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 AIPGDQHPES(0.928)PVHT(0.072)EPMGIQGR;AIPGDQHPES(0.994)PVHT(0.006)EPMGIQGR;AIPGDQHPES(0.895)PVHT(0.105)EPMGIQGR;AIPGDQHPES(0.997)PVHT(0.003)EPMGIQGR;AIPGDQHPES(1)PVHTEPMGIQGR 100.01 8.6369e-05 132610000.0 178785.0 174389.0 186853.0 147415.0 167936.0 192665.0 164226.0 150153.0 174173.0 137055.0 True False 176235.49311484647 173985.21298492808 171490.66761343848 158256.3908620241 158058.33465487917 184425.16707405105 172728.8187160106 157129.656540476 154555.80261699978 160744.77413569193 1.0963684142296166 1.082369326906138 1.0668506552423 0.9845196630058575 0.9832875470119793 1.1473167203455674 1.0745532453216948 0.9775102014068323 0.9614981479057741 1.0 17.294412310272627 -1.5228787453123689 0.15951751202946055 0.9807113702974934 1.4047619380447498 0.2330058364745915 0.05276543018447381 114.88508158309163 1.187234692882601 0.17886077726299365 11.434485508793948 0.029999999997787356 1.5228787453123689 0.42405056774725636 AIPNGFGTSPLTPS(ph)AR ddPTM_PC-9_Lapatinib_30min_R1 2 AIPNGFGTSPLTPSAR 16 0 J3QSD2;J3QRZ1;A6NIZ0;Q9GZM8-3;Q9GZM8;Q9GZM8-2 J3QSD2 NDEL1 Nuclear distribution protein nudE-like 1 1 AIPNGFGT(0.001)S(0.083)PLT(0.083)PS(0.833)AR;AIPNGFGT(0.005)S(0.069)PLT(0.036)PS(0.89)AR 69.878 0.020728 13161500.0 57968.0 51216.0 45855.0 53133.0 49135.0 46240.0 45916.0 39872.0 50284.0 40558.0 True False 57141.36568997076 51097.41249870166 42084.97890541876 57040.578066492046 46244.97590312675 44262.422990704705 48293.30581128653 41724.5986798923 44620.48640600562 47568.39625986201 1.2012464195305732 1.0741882534689826 0.8847256206728555 1.1991276257220094 0.9721785794604988 0.9305006363658539 1.0152393103072974 0.8771495774621966 0.9380279747555033 1.0 15.537715766066 -1.5228787452803376 0.46199195387894104 0.9530250438944337 6.5396529118903555 0.38575426425281456 0.08687120286138697 100.68056183971505 1.179690942358888 0.05325063857198778 534.5416462393803 0.029999999999999995 1.5228787452803376 5.586627867995922 AIPQLQGYLR ddPTM_PC-9_Lapatinib_30min_R1 1 AIPQLQGYLR 10 0 Q02878 Q02878 RPL6 60S ribosomal protein L6 0 107.29 0.010103000000000001 5544800.0 23095.0 31029.0 23314.0 24630.0 28968.0 29953.0 26726.0 27442.0 26906.0 25174.0 False True 22765.6610648957 30957.154256916067 21397.21291464254 26441.372363271395 27264.15919327927 28671.980013853314 28109.741508677664 28717.05550194632 23875.562947259292 29525.29235775349 0.7710562452370543 1.0484961124791898 0.7247079099294177 0.8955498913570541 0.9234170779047194 0.9710989366824647 0.9520563308256592 0.9726256104083955 0.808647808054285 1.0 14.849663724726256 -6.18042081622577 3.866171566734588 0.9393307503921879 0.8610441303806406 0.15225187675958574 0.09248662038973737 0.48993788728493187 13.888274135552093 0.02703822480296371 0.03530223253192455 6.600535691297576e-07 6.18042081622577 -0.07828662001154729 AIPTVNHSGTFS(ph)PQAPVPTTVPVVDVR ddPTM_PC-9_AZD4547_30min_R2 2 AIPTVNHSGTFSPQAPVPTTVPVVDVR 27 0 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5;B1AL79 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 AIPTVNHSGT(0.001)FS(0.998)PQAPVPT(0.001)T(0.001)VPVVDVR;AIPTVNHSGT(0.003)FS(0.997)PQAPVPTTVPVVDVR 108.08 2.4309999999999997e-10 51885000.0 48432.0 42297.0 51484.0 76527.0 69104.0 62610.0 49063.0 76958.0 52876.0 63652.0 True False 63832.3685518188 55968.67808708373 50801.28852095196 58884.882480363965 59510.102421867035 58694.986802424784 53429.511952374865 65065.90941891031 55670.9174115065 61423.56285416098 1.0392163135078487 0.911192309374354 0.827065154809895 0.9586692751798744 0.9688481041577302 0.9555776981186406 0.8698536761736448 1.0592988487723747 0.9063446473088336 1.0 15.906504577355769 -8.10849079825313 0.631139328978484 0.9932550073643669 0.9312573024857005 0.047297128965147706 0.06749261496226507 2.1198924376595247 1.8972859868637948 0.06616869922259601 0.03145269352976723 7.789493186052325e-09 8.10849079825313 -0.061997704878666404 AIPTVNHSGTFS(ph)PQAPVPTTVPVVDVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AIPTVNHSGTFSPQAPVPTTVPVVDVR 27 0 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5;B1AL79 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 AIPTVNHS(0.02)GT(0.015)FS(0.965)PQAPVPTTVPVVDVR;AIPT(0.004)VNHS(0.094)GT(0.224)FS(0.678)PQAPVPTTVPVVDVR 74.627 3.2538e-05 22879300.0 39072.0 33419.0 50850.0 47535.0 51778.0 45355.0 47613.0 44128.0 40016.0 35038.0 True False 45686.1178928237 36736.61746152323 52062.456849698916 44871.76806054933 41632.47259148304 42976.50395708571 43102.751951731465 42969.686757480835 40601.15829716566 41390.112039344625 1.103793047223341 0.8875698965637524 1.2578476907771927 1.0841180622534945 1.0058555181466537 1.0383277995535043 1.041377996531124 1.0381630935580628 0.9809385937049651 1.0 15.336998533369842 -6.252868994916572 22.977666606556944 1.0215928955882096 1.0818145599099185 0.12443570591211972 0.0851585481228506 526.878673825232 1412585.541082974 0.025384049097142848 0.03217265765759436 5.586386828787472e-07 6.252868994916572 0.060221664321708834 AIPTVNHSGTFS(ph)PQAPVPTTVPVVDVR ddPTM_PC-9_Lapatinib_30min_R1 2 AIPTVNHSGTFSPQAPVPTTVPVVDVR 27 0 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5;B1AL79 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 AIPTVNHS(0.03)GT(0.022)FS(0.946)PQAPVPT(0.001)T(0.001)VPVVDVR;AIPTVNHSGT(0.002)FS(0.998)PQAPVPTTVPVVDVR 120.31 2.0625e-12 36661000.0 61189.0 68919.0 81474.0 59442.0 72598.0 66874.0 62598.0 59875.0 65974.0 46145.0 True False 60316.43363931168 68759.42228987059 74775.52221873509 63813.56297269908 68327.92837315967 64013.954910907996 65839.01814563366 62657.011084433936 58543.31338298092 54121.10176565244 1.114471651011197 1.2704734391329087 1.3816334069198648 1.1790883941907828 1.2625006909324135 1.1827910523346732 1.2165128941890444 1.157718690867427 1.081709563794117 1.0 15.723903588702475 -8.254572816054306 0.8201286495445954 0.9975936881870052 1.2461805995980213 0.5787344049410311 0.06606967064961738 0.41972600483985467 0.6080977614582732 0.06344016462798986 0.024247733379859623 5.564513289346977e-09 8.254572816054306 0.24858691141101608 AIPVS(ph)PSAVEEDEDEDGHTVVATAR ddPTM_PC-9_AZD4547_30min_R2 4 AIPVSPSAVEEDEDEDGHTVVATAR 25 0 A0A087X0K9;G5E9E7;Q07157-2;H0Y3R8;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 AIPVS(0.78)PS(0.22)AVEEDEDEDGHTVVATAR;AIPVS(0.5)PS(0.5)AVEEDEDEDGHTVVATAR;AIPVS(0.847)PS(0.153)AVEEDEDEDGHTVVATAR;AIPVS(0.863)PS(0.137)AVEEDEDEDGHTVVATAR 189.11 2.7531999999999997e-21 279259000.0 109143.89 113494.1 154646.8 215032.7 175615.1 149804.57 123964.4 187239.9 133245.8 152990.1 True False 143849.37668605847 150178.84832690953 152596.08238757588 165460.23323709748 151233.974702281 140437.26655634737 134996.99144913655 158306.2757998623 140288.90096130804 147633.96316556202 0.9743650688611578 1.0172378029200069 1.0336109599418473 1.1207464033973296 1.0243847110754711 0.9512531096849035 0.9144033564806906 1.0722890072545974 0.9502481539697138 1.0 17.17166512574061 -6.609468969726514 6.738354293784817 0.9786030098349919 1.0394229038807377 0.2338180900899136 0.05127871415763168 0.33610084832945974 21.688137459401652 0.01762685856363014 0.01761455327025152 2.4577122280999336e-07 6.609468969726514 0.060819894045745726 AIPVS(ph)PSAVEEDEDEDGHTVVATAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AIPVSPSAVEEDEDEDGHTVVATAR 25 0 A0A087X0K9;G5E9E7;Q07157-2;H0Y3R8;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 AIPVS(0.5)PS(0.5)AVEEDEDEDGHTVVATAR;AIPVS(0.5)PS(0.5)AVEEDEDEDGHTVVATAR;AIPVS(0.965)PS(0.035)AVEEDEDEDGHTVVATAR 170.55 5.8297e-11 125274600.0 150526.0 157978.0 191955.0 196663.0 233879.0 215092.0 201103.0 233785.0 196532.0 167244.0 True False 176007.0787759826 173661.01179977035 196531.9351933911 185644.60970004895 188052.08886444973 203812.1968721745 182053.06798036385 227648.39146568236 199405.9086979851 197564.0132972248 0.8908863301495556 0.8790113589082966 0.9947759812801485 0.9396681440195097 0.9518539622979573 1.031626121937246 0.9214890148362924 1.1522766098256831 1.0093230309003152 1.0 17.591960655338063 -5.792400016125862 0.4615817326648458 1.044264014005003 0.8501222748275415 0.40714793715770836 0.058497561988166136 2.002060042872077 0.636969362119515 0.047234602879910804 0.1944790346620933 1.6128723022825653e-06 5.792400016125862 -0.19414173917746147 AIPVS(ph)PSAVEEDEDEDGHTVVATAR ddPTM_PC-9_Lapatinib_30min_R1 2 AIPVSPSAVEEDEDEDGHTVVATAR 25 0 A0A087X0K9;G5E9E7;Q07157-2;H0Y3R8;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 AIPVS(0.788)PS(0.212)AVEEDEDEDGHTVVATAR;AIPVS(0.939)PS(0.061)AVEEDEDEDGHTVVATAR 141.12 8.742200000000002e-07 2246200.0 17140.9 11085.6 13437.2 12359.099999999999 11672.7 13236.599999999999 11287.7 12904.400000000001 15431.8 11957.3 True False 16896.467622743916 11059.931974297238 12332.44528509199 13268.029442748992 10986.134735411168 12670.501474021667 11872.121874859717 13503.985533828298 13693.708179941872 14024.103372899257 1.2048162491011962 0.7886373681236475 0.8793749559008317 0.9460875387148576 0.7833751964950014 0.9034803250599718 0.8465512239307851 0.9629125780635605 0.9764409043364687 1.0 13.77562091503075 -7.928299502921676 7.209520086960778 0.9822276692801181 0.898474338176343 0.07932010433092873 0.11174521733083874 0.5188591190478972 43.02832498846304 0.05927739546768342 0.028189940111183212 1.1795069306057473e-08 7.928299502921676 -0.08375333110377503 AIPVSPS(ph)AVEEDEDEDGHTVVATAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AIPVSPSAVEEDEDEDGHTVVATAR 25 0 A0A087X0K9;G5E9E7;Q07157-2;H0Y3R8;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 AIPVS(0.038)PS(0.962)AVEEDEDEDGHTVVATAR;AIPVS(0.093)PS(0.907)AVEEDEDEDGHTVVATAR;AIPVS(0.166)PS(0.834)AVEEDEDEDGHTVVATAR;AIPVS(0.004)PS(0.996)AVEEDEDEDGHTVVATAR 186.7 4.432e-21 87653100.0 82099.1 86915.5 104093.2 105067.5 119463.5 106493.0 118596.2 117826.79999999999 115292.8 88646.7 True False 95996.8560988614 95543.8964354717 106575.17666365953 99180.90860843091 96055.48475091041 100908.31960978793 107361.90937386699 114733.97134781395 116978.73908745173 104717.6449831089 0.9167209223846261 0.9123953890567638 1.017738478370577 0.9471269968344774 0.9172807960530844 0.9636228892090208 1.025251373741117 1.095650798548045 1.117087183409449 1.0 16.676145032128687 -7.396868838624714 2.5264554196639444 1.078829356712194 0.9450289344519206 0.6660039536115694 0.040298737256566554 0.1711287013636331 2.1267371100120354 0.020475570491474863 0.012304053871745555 4.009878017592974e-08 7.396868838624714 -0.13380042226027344 AIPVSPS(ph)AVEEDEDEDGHTVVATAR ddPTM_PC-9_Lapatinib_30min_R1 3 AIPVSPSAVEEDEDEDGHTVVATAR 25 0 A0A087X0K9;G5E9E7;Q07157-2;H0Y3R8;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 AIPVS(0.034)PS(0.966)AVEEDEDEDGHTVVATAR;AIPVS(0.239)PS(0.761)AVEEDEDEDGHTVVATAR;AIPVS(0.135)PS(0.865)AVEEDEDEDGHTVVATAR 192.89 1.2757e-22 197902000.0 196712.0 166421.0 204260.0 166008.0 201377.0 198952.0 182329.0 174340.0 234886.0 186210.0 True False 193906.8508074373 166035.66239937537 187466.53126640184 178216.78210645384 189532.40078241492 190443.28673976383 191769.1034773513 182440.47285946095 208430.66522076685 218396.1503907709 0.8878675309087843 0.7602499499294828 0.8583783685333856 0.8160252906819782 0.8678376447720769 0.8720084415362098 0.8780791379986485 0.835364874944108 0.9543696848494213 1.0 17.736587900927674 -8.659635828334391 0.43623634797377764 1.0118809770793173 0.8260694560937092 0.630712251504976 0.038727283088284985 0.8819237664272399 0.4018354554212475 0.055235593389089246 0.025316790445753367 2.189596910744072e-09 8.659635828334391 -0.18581152098560816 AIQEGANSIVSSLHQAAAAACLS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 AIQEGANSIVSSLHQAAAAACLSR 24 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 AIQEGANSIVSS(0.001)LHQAAAAACLS(0.999)R;AIQEGANSIVSSLHQAAAAACLS(1)R 77.488 0.00092922 0.0 18248.6 16076.8 24781.0 32400.0 23554.5 25761.0 19841.1 21842.4 14621.5 20499.5 True False 24051.275205540125 21273.311201040928 24452.38774838225 24930.680575010007 20284.364255265507 24150.160597624417 21606.91946269624 18467.158968419222 15394.362639616142 19781.818744562188 1.2158272965751222 1.075397134901397 1.2361041249103524 1.2602825299803733 1.0254044138808756 1.220826098422474 1.0922615226487076 0.9335420168833388 0.7782076480630927 1.0 14.271887453428887 -7.72302130919939 2.900897594551091 0.880044356073409 1.167705012219874 0.6643311168760113 0.08536390503461469 0.1482089092546661 2.5194649617130254 0.04884369176786752 0.02318986698763079 1.8922507707274945e-08 7.72302130919939 0.28766065614646497 AIQEGANSIVSSLHQAAAAACLS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AIQEGANSIVSSLHQAAAAACLSR 24 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 AIQEGANSIVSSLHQAAAAACLS(1)R 79.304 0.00074156 0.0 4684.3 5260.0 5869.4 7492.8 7538.1 6365.8 6058.2 5230.7 7193.7 4638.1 True False 5477.259470857751 5782.1780378710355 6009.348755823455 7073.002707985357 6061.063417703623 6031.966241649563 5484.32343843025 5093.399667384763 7298.894253356672 5478.950814820603 0.9996913014881832 1.055344030873612 1.0968064797311414 1.2909410847151304 1.1062452689497413 1.100934548514845 1.000980593509822 0.9296304784498299 1.3321700632196056 1.0 12.419683937122752 -7.021957227954195 21.98087943128814 1.0585634825167294 1.114867838021987 0.02720887789151616 0.12101273443831508 637.2369086655947 637919.6737576418 0.046355703464529975 0.03633570525393447 9.506984197918397e-08 7.021957227954195 0.056304355505257586 AIQGGT(ph)S(ph)HHLGQNFS(ph)KMFEIVFEDPK ddPTM_PC-9_AZD4547_30min_R2 1 AIQGGTSHHLGQNFSKMFEIVFEDPK 26 1 P07814 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 3 AIQGGT(1)S(1)HHLGQNFS(1)KMFEIVFEDPK 42.254 0.024746 2791600.0 945.07 1074.3 2474.3 3704.6 3054.0 2812.0 2419.5 3062.7 1159.4 2911.0 True False 1245.5826013228316 1421.546465918484 2441.4891653211002 2850.561705499447 2630.0048158772574 2636.165195470666 2634.8308128074323 2589.4300888445196 1220.6835170379893 2809.08677603944 0.44341193442197296 0.5060528845330784 0.8691398165931281 1.0147645597187578 0.9362490465977445 0.9384420652136002 0.9379670415601425 0.9218049477614869 0.4345481696934416 1.0 11.45588547638453 -5.245848969438153 4.3620133460941615 0.8913642944105136 0.4613597284353663 0.5220763477127404 0.15606390102342121 0.1505410874868106 7.329148214271834 0.040868618292906944 0.10787213104504802 5.6774200945202e-06 5.245848969438153 -0.43000456597514725 AIS(ph)ETEENSDELSGER ddPTM_PC-9_AZD4547_30min_R2 2 AISETEENSDELSGER 16 0 A7UKX8;F5GWH7;J3KN53;E7EPE2;Q00987-8;Q00987-9;Q00987;Q00987-11 A7UKX8 mdm2;MDM2 E3 ubiquitin-protein ligase Mdm2 1 AIS(0.974)ET(0.025)EENS(0.001)DELSGER;AIS(0.91)ET(0.09)EENSDELSGER 236.27 4.2396999999999984e-109 12168000.0 18574.6 12079.4 21458.4 36218.0 34362.0 30231.0 24457.0 28720.0 25910.0 28878.0 True False 24480.93642431891 15983.829824458453 21173.84759533051 27868.49966252197 29591.429431294797 28340.650790993524 26633.625620513078 24281.983919944687 27279.54970368664 27866.990009779118 0.8784923099239649 0.5735757546419398 0.7598182504784391 1.0000541735129025 1.0618810794029256 1.0169971992327909 0.9557410258936029 0.8713529488266807 0.9789198508383455 1.0 14.766269560947794 -5.7063190127580405 5.079499041694727 0.9819463669282114 0.7142022447096957 0.6492684263226143 0.08286706862383937 0.11533390848731288 6.143529678878212 0.02295476515314632 0.03981102378377031 1.966441301695446e-06 5.7063190127580405 -0.2677441222185156 AIS(ph)ETEENSDELSGER ddPTM_PC-9_Lapatinib_30min_R1 2 AISETEENSDELSGER 16 0 A7UKX8;F5GWH7;J3KN53;E7EPE2;Q00987-8;Q00987-9;Q00987;Q00987-11 A7UKX8 mdm2;MDM2 E3 ubiquitin-protein ligase Mdm2 1 AIS(0.5)ET(0.5)EENSDELSGER;AIS(0.917)ET(0.083)EENSDELSGER 302.84 2.2132999999999992e-128 19055600.0 16695.8 19204.3 23058.4 20183.1 29027.4 33136.3 34150.2 30548.4 40351.7 33343.1 True False 16457.71483036525 19159.833623258666 21162.627359998 21667.432502847856 27320.065402064134 31719.13769348807 35918.33025778807 31967.79018641708 35806.866623761336 39106.410408111966 0.4208444257249286 0.4899409949240517 0.5411549446534774 0.5540634457810864 0.6986083641263338 0.8110981642771404 0.9184767889189189 0.8174565206267539 0.9156265238891321 1.0 15.25511749618576 -6.422345027521131 0.6625146739481197 0.942819096420883 0.4159783620800753 0.9545398055617863 0.041352055125387276 0.16364675892189587 0.15782932957280138 0.029586122846010324 0.045540360498201 3.781420484247314e-07 6.422345027521131 -0.5268407343408077 down AIS(ph)SANLLVR ddPTM_PC-9_AZD4547_30min_R2 4 AISSANLLVR 10 0 B7WPE2;Q32P44;G3V1D0;H0Y3M3;Q32P44-2 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 AIS(0.828)S(0.172)ANLLVR;AIS(0.5)S(0.5)ANLLVR;AIS(0.847)S(0.153)ANLLVR;AIS(0.916)S(0.084)ANLLVR 166.24 0.00020482 141494000.0 125203.0 106900.5 122046.0 127723.0 137851.0 116014.0 108542.0 133764.0 101729.0 105576.0 True False 165014.94961581903 141453.99607178508 120427.59029656033 98278.43565067904 118712.76813146527 108759.62624016138 118202.02772628432 113093.8473909288 107106.18725613022 101879.81637483316 1.6197020713965657 1.388439841227744 1.1820554314064207 0.9646506947862565 1.1652236169596226 1.0675286834049271 1.1602104512183156 1.110071174204293 1.0512993747659336 1.0 16.636508738893042 -5.051299774267753 1.8290026913578918 1.0848558345585668 1.6574502343775965 0.8867955507459371 0.06289649331791859 0.15319544735237953 0.774227831503564 0.017331217630239378 0.12618441670530653 8.885875534469237e-06 5.051299774267753 0.5725943998190297 AIS(ph)SANLLVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AISSANLLVR 10 0 B7WPE2;Q32P44;G3V1D0;H0Y3M3;Q32P44-2 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 AIS(0.77)S(0.23)ANLLVR;AIS(0.84)S(0.16)ANLLVR;AIS(0.857)S(0.143)ANLLVR;AIS(0.941)S(0.059)ANLLVR 132.14 0.00015631 135913000.0 67116.0 82795.0 76889.0 63079.0 67814.0 59510.0 61496.0 44120.0 55735.0 46934.5 True False 78477.41319857599 91014.34042690718 78722.32536315644 59544.88813487722 54526.333506872186 56389.19083863236 55670.65368751556 42961.89674900409 56550.018934739266 55443.35331670245 1.4154521417616792 1.6415735157110145 1.4198694821628175 1.073977033725685 0.9834602390553097 1.017059529508021 1.004099686566841 0.7748791185770812 1.0199602937382835 1.0 15.758726896531687 -5.7707910513943945 2.567419183442206 0.9615639290878302 1.5348179752974773 0.8870414997902629 0.08471276217228146 0.08052247964290173 1.0825756513892917 0.02498803835471605 0.045019092167066586 1.6951531796771588e-06 5.7707910513943945 0.5732540462096472 AIS(ph)SANLLVR ddPTM_PC-9_Lapatinib_30min_R1 3 AISSANLLVR 10 0 B7WPE2;Q32P44;G3V1D0;H0Y3M3;Q32P44-2 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 AIS(0.712)S(0.288)ANLLVR;AIS(0.5)S(0.5)ANLLVR;AIS(0.931)S(0.069)ANLLVR 136.01 0.00011453 75459000.0 31902.3 50003.0 47980.0 40949.0 45116.0 46588.0 51268.0 45615.0 47274.0 40773.0 True False 31447.367351834688 49887.221125675154 44035.26960815598 43960.526061859535 42462.36558146873 44595.5398419323 53922.406183749394 47734.43942574454 41949.50430271077 47820.55872339251 0.6576118763842776 1.04321702751816 0.9208438960922287 0.9192808958201328 0.8879521008335124 0.932559991611252 1.1275988324530393 0.9981991156116324 0.8772273980602869 1.0 15.545343365783822 -7.014142127685697 24.037626627467773 1.0048167185065326 0.8995285456254906 0.20279865902835426 0.10562672195314127 698.6972755640526 1187587.132625589 0.03840101191944012 0.030996977836811088 9.679610284397472e-08 7.014142127685697 -0.10528817288104209 AIS(ph)SDMFFGR ddPTM_PC-9_AZD4547_30min_R2 2 AISSDMFFGR 10 0 Q8N6H7;E9PMU9;H0YDN9;A0A0D9SF70;G5E9L0;Q8N6H7-3;Q8N6H7-2 Q8N6H7 ARFGAP2 ADP-ribosylation factor GTPase-activating protein 2 1 AIS(0.941)S(0.059)DMFFGR;AIS(0.938)S(0.062)DMFFGR 77.288 0.019348 9071800.0 50502.0 48421.0 65360.0 88799.0 121702.0 86116.0 59502.0 70971.0 58728.0 66652.0 True False 66560.585493144 64072.141325736644 64493.28369453469 68327.76248087393 104805.77802943459 80731.15290652642 64797.56272935231 60004.06270133694 61832.242184411785 64318.533767289824 1.0348585640021912 0.9961691844151073 1.0027169451324425 1.06233395692896 1.6294802118566822 1.25517713445737 1.0074477593627313 0.9329202515473529 0.9613440879751136 1.0 15.972946898150083 -7.41980393812203 5.572042821438103 0.9620924582064649 1.164455435550205 0.21792315323095846 0.17568594986573452 0.4072919508495854 18.062199358941086 0.08551277503899309 0.056593194882629816 3.8036107125156346e-08 7.41980393812203 0.2023629773437401 AIS(ph)SDMFFGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AISSDMFFGR 10 0 Q8N6H7;E9PMU9;H0YDN9;A0A0D9SF70;G5E9L0;Q8N6H7-3;Q8N6H7-2 Q8N6H7 ARFGAP2 ADP-ribosylation factor GTPase-activating protein 2 1 AIS(0.963)S(0.037)DMFFGR 68.355 0.036284 6679800.0 42730.0 50605.0 66107.0 53190.0 68116.0 65974.0 42006.0 54582.0 46700.0 36549.0 True False 49963.34504403041 55628.7299632061 67683.24159219353 50209.93674430669 54769.15877479732 62514.207299410664 38026.8875828961 53149.28033440939 47382.89915227998 43175.044378275175 1.1572274160572946 1.2884463875895253 1.5676472964148334 1.1629388566319883 1.268537405426642 1.4479245638220253 0.8807608221482334 1.2310185455455618 1.0974603462393222 1.0 15.397910040205435 -7.25283139260222 24.998458200371317 1.0715614701227647 1.3166243484753277 0.45158799076549505 0.14142436859160343 638.3941627595658 1853964.355923593 0.05455325036448263 0.04155555854301257 5.5868705332241e-08 7.25283139260222 0.24506287835256302 AIS(ph)SDMFFGR ddPTM_PC-9_Lapatinib_30min_R1 3 AISSDMFFGR 10 0 Q8N6H7;E9PMU9;H0YDN9;A0A0D9SF70;G5E9L0;Q8N6H7-3;Q8N6H7-2 Q8N6H7 ARFGAP2 ADP-ribosylation factor GTPase-activating protein 2 1 AIS(0.958)S(0.042)DMFFGR;AIS(0.828)S(0.172)DMFFGR;AIS(0.937)S(0.063)DMFFGR 107.11 0.0022188000000000004 3235450.0 15326.699999999999 11192.3 13201.0 12006.4 15266.3 15045.400000000001 12962.1 14823.199999999999 18727.3 16380.4 True False 15108.138447427453 11166.384917002868 12115.664737333616 12889.390708176279 14368.366248700602 14401.943314540405 13633.214113957609 15511.939986752082 16618.034266788418 19211.730314488967 0.7864017555999786 0.5812274445983391 0.6306389137784383 0.6709125361006889 0.7478954791419474 0.7496432168672933 0.7096296840933587 0.807420244445832 0.8649941465322125 1.0 14.229699841484333 -8.320596560846512 0.5008140297564102 1.009849272555734 0.6586855278095974 0.7697915448028407 0.05485871817034362 0.433137920808114 0.277661466186359 0.06222057527332192 0.032940411333997 4.779730820064796e-09 8.320596560846512 -0.35116374474613654 AIS(ph)TGSLASSTLNK ddPTM_PC-9_AZD4547_30min_R2 2 AISTGSLASSTLNK 14 0 Q12923-3;Q12923;Q12923-4 Q12923-3 PTPN13 Tyrosine-protein phosphatase non-receptor type 13 1 AIS(0.998)T(0.001)GSLASSTLNK;AIS(0.874)T(0.124)GS(0.002)LASSTLNK 143.38 0.00016477 10721300.0 32186.0 33035.0 48730.0 68826.0 71614.0 60193.0 50033.0 79928.0 61006.0 63134.0 True False 42420.47848961097 43712.917715365445 48083.80836038362 52959.229051099996 61671.632247620815 56429.122194511336 54485.84007323587 67576.96416272072 64230.65261378261 60923.69787649399 0.69628863591975 0.7175026999178766 0.7892463858293745 0.8692714148517419 1.0122765754081942 0.926226151093222 0.8943291686543863 1.1092065406094422 1.0542802694608682 1.0 15.894715891075416 -5.597841186593818 0.5610328543385339 1.035920447055577 0.5919285846235157 0.8241084946628547 0.05602312278824213 0.7675885651456831 0.34238660677642574 0.03884108062456089 0.20026069397726393 2.524403731160123e-06 5.597841186593818 -0.44399186243206124 AIS(ph)TGSLASSTLNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AISTGSLASSTLNK 14 0 Q12923-3;Q12923;Q12923-4 Q12923-3 PTPN13 Tyrosine-protein phosphatase non-receptor type 13 1 AIS(0.943)T(0.056)GSLASSTLNK 123.95 3.964e-05 4420100.0 8358.2 13323.0 14867.0 12856.0 19881.0 15323.0 15926.0 17727.0 14882.0 12002.0 True False 9773.07817802516 14645.61939136043 15221.485663411482 12135.719999714362 15985.460766952647 14519.43490540015 14417.373985744976 17261.685033309066 15099.621096022072 14177.867592220276 0.6893193291907926 1.032991689060266 1.0736089587805053 0.8559622891649454 1.1274940087410774 1.0240915857732582 1.0168929771678867 1.2175092566657169 1.0650135500142195 1.0 13.791352941360318 -4.761678513541122 5.641541545157688 1.0496901456337964 0.6731282434764778 0.5989279496357306 0.08761004836925962 0.10191507272875798 10.8687896000594 0.022133286335575982 0.14961302939405932 1.731097329710801e-05 4.761678513541122 -0.37656190215731855 AIS(ph)TGSLASSTLNK ddPTM_PC-9_Lapatinib_30min_R1 2 AISTGSLASSTLNK 14 0 Q12923-3;Q12923;Q12923-4 Q12923-3 PTPN13 Tyrosine-protein phosphatase non-receptor type 13 1 AIS(0.988)T(0.012)GSLASSTLNK;AIS(0.99)T(0.01)GSLASSTLNK 178.23 7.6717e-05 9606600.0 52390.0 44048.0 45639.0 37001.0 38761.0 42428.0 35096.0 32758.0 45785.0 30872.0 True False 51642.90899285066 43946.009562301035 41886.73759163466 39722.17697171764 36481.15418705804 40613.45334449869 36913.09915395313 34280.05626895845 40628.21116257588 36208.184065645764 1.426277244371648 1.2137037715734798 1.1568306633575887 1.0970496863278472 1.007538906699032 1.1216650155905674 1.019468391097144 0.9467488401740445 1.1220725979772022 1.0 15.144028203279248 -1.5228787452803552 0.5421055136393705 1.0255614300002702 18.016724940246366 0.8432993448916751 0.05174358342377963 45.85830556094258 0.43055541118890145 0.02528362727586224 904.4235231651427 0.029999999999998785 1.5228787452803552 16.991163510246096 AIS(ph)TPETPLTK ddPTM_PC-9_AZD4547_30min_R2 1 AISTPETPLTK 11 0 E9PIQ6;A0A3B3ITS5;Q14181 E9PIQ6 POLA2 DNA polymerase alpha subunit B 1 AIS(0.5)T(0.5)PETPLTK 147.58 0.0002602 9553300.0 77704.0 90612.0 100780.0 113730.0 91555.0 79805.0 88079.0 113260.0 81126.0 82326.0 True False 102412.25565639486 119900.55698576327 99443.59135151777 87511.30561098413 78844.16860433591 74814.780734188 95917.86036836791 95758.26945588223 85414.15473798841 79443.79179808433 1.2891159062080968 1.5092501789253026 1.2517477967852448 1.101549959163635 0.9924522334574306 0.9417322491899491 1.2073676016390853 1.2053587484754384 1.075152039004866 1.0 16.277646862910963 -5.592315019476498 3.1715457393877116 1.0793425429492285 1.3989823938149828 0.6540882094291414 0.09542150030262263 0.15369063946381264 3.10464987839225 0.0284326332750452 0.05600139130605265 2.5567306661520345e-06 5.592315019476498 0.3196398508657543 AISAPT(ph)SPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AISAPTSPTR 10 0 B0QY95;Q9NQG6;Q9NQG6-2 B0QY95 MIEF1 Mitochondrial dynamics protein MID51 1 AIS(0.011)APT(0.592)S(0.395)PT(0.001)R 82.494 0.036278 23603000.0 99246.0 122480.0 133850.0 140000.0 153110.0 122770.0 164430.0 138710.0 129680.0 96739.0 True False 116046.38760214923 134639.00495787922 137041.49162895206 132156.25388612374 123109.19460933161 116331.72507576695 148854.000029891 135069.0094753933 131576.32466954322 114277.01491449721 1.0154831895895766 1.17818097592606 1.1992043345854577 1.1564552502968677 1.0772874554121201 1.0179800825459704 1.3025716513619516 1.1819438018787314 1.1513804833630759 1.0 16.802175730976884 -7.241134643402323 24.995732698556104 1.174136008787244 1.1156773727292857 0.05866740285827898 0.09000086730808006 2172.5324374433867 2674454.4088887675 0.03451426272942762 0.026698655577220943 5.7393849767973604e-08 7.241134643402323 -0.0584586360579582 AISAPTS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 2 AISAPTSPTR 10 0 B0QY95;Q9NQG6;Q9NQG6-2 B0QY95 MIEF1 Mitochondrial dynamics protein MID51 1 AISAPT(0.003)S(0.988)PT(0.009)R;AISAPT(0.082)S(0.914)PT(0.003)R 139.31 0.00012086 68677000.0 413860.0 420130.0 572280.0 719390.0 604190.0 459280.0 534240.0 586860.0 428480.0 530850.0 True False 545458.8711772319 555928.8064100643 564691.1932788902 553545.7499647058 520308.64757854625 430561.14899565 581786.3250399833 496174.27170121064 451128.57804074284 512265.10307816573 1.064798027231617 1.085236536842987 1.1023417169854042 1.0805845384323225 1.0157019177219908 0.84050454814985 1.1357133670516872 0.9685888590101758 0.880654519173651 1.0 18.96653108918288 -6.392146297182712 4.142527209278541 0.9699729603336562 1.084387700054326 0.3589416546569987 0.0737014170670568 0.27480501790242007 7.915706813832561 0.023621768404033718 0.026856962346409045 4.053719581540003e-07 6.392146297182712 0.11441473972066984 AISAPTS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AISAPTSPTR 10 0 B0QY95;Q9NQG6;Q9NQG6-2 B0QY95 MIEF1 Mitochondrial dynamics protein MID51 1 AIS(0.002)APT(0.164)S(0.833)PT(0.002)R;AIS(0.005)APT(0.055)S(0.879)PT(0.061)R 89.561 0.009270700000000002 60302000.0 401210.0 431340.0 466740.0 546920.0 564310.0 528220.0 596530.0 491140.0 469650.0 445660.0 True False 469126.92874129215 474160.5845732488 477868.8517213059 516277.84553856374 453737.5064332295 500519.2133218347 540022.3598968006 478248.09540584474 476517.74275949266 526454.6301573805 0.8911060932279187 0.9006675170308623 0.9077113664637158 0.9806692086347983 0.8618739022156332 0.9507357038007386 1.0257718879504663 0.9084317394318961 0.9051449364535753 1.0 19.005949679634014 -6.9688453349028245 24.844186446058615 0.9573561033492469 0.9113870739062512 0.24062066360831247 0.044056925792889924 311.3283505318085 248266.75327443582 0.01581424485414088 0.013946703705455933 1.0743719598185062e-07 6.9688453349028245 -0.045969029442995746 AISESLDIDNPS(ph)FAS(ph)IIEKMAK ddPTM_PC-9_Lapatinib_30min_R1 1 AISESLDIDNPSFASIIEKMAK 22 1 Q5CZC0-2;Q5CZC0 Q5CZC0-2 FSIP2 Fibrous sheath-interacting protein 2 2 AISES(0.001)LDIDNPS(0.999)FAS(1)IIEKMAK 58.92 0.028630000000000003 0.0 16315.0 13710.0 15666.0 13376.0 15738.0 10917.0 9718.7 9938.1 14428.0 10880.0 True False 16082.345108195426 13678.255337339888 14378.001952508797 14359.71566102795 14812.321782098488 10450.10535876997 10221.886732035688 10399.860406817756 12802.966706424486 12760.593503311286 1.2603132529864045 1.0719137267236414 1.1267502525472506 1.125317224257767 1.1607862736364727 0.8189356832077004 0.8010510427577823 0.814998174193 1.0033206294912698 1.0 13.639407810875696 -6.757176785910241 24.999993140192643 0.8706853479123957 1.1421791151538934 0.7232454372080908 0.08043877142977619 55.222198822141884 323876.62838425854 0.0266258703596399 0.025735648230160512 1.7491345329360581e-07 6.757176785910241 0.27149376724149765 AISS(ph)ANLLVR ddPTM_PC-9_Lapatinib_30min_R1 1 AISSANLLVR 10 0 B7WPE2;Q32P44;G3V1D0;H0Y3M3;Q32P44-2 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 AIS(0.248)S(0.752)ANLLVR 152.96 0.00017234 51644000.0 26515.0 29061.0 36721.0 24194.0 33025.0 39859.0 35310.0 32454.0 31461.0 27756.0 True False 26136.89123774453 28993.7110400025 33701.94112715915 25973.307468818046 31082.534429648134 38154.32348586717 37138.17902684309 33961.9313191519 27917.530880982853 32553.587617454774 0.8028881960687583 0.8906456449812764 1.0352757896671472 0.7978631349034945 0.9548113343114943 1.172046655324999 1.1408321400167312 1.0432623192947863 0.8575869181931232 1.0 14.99052892609534 -6.530433749503719 24.85756692893996 1.0528965008968592 0.8911633808106256 0.36261116250708014 0.10011604509438665 192.33834530577255 632828.5845438975 0.03418286960912715 0.03424856506205311 2.948263192203815e-07 6.530433749503719 -0.16173312008623353 AISSRET(ph)DRLINS(ph)ELGSPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AISSRETDRLINSELGSPSR 20 2 Q68CP4-2;Q68CP4 Q68CP4-2 HGSNAT Heparan-alpha-glucosaminide N-acetyltransferase 2 AIS(0.116)S(0.138)RET(0.746)DRLINS(0.886)ELGS(0.1)PS(0.014)R 70.02 0.027719 0.0 10844.0 15410.0 15584.0 13273.0 14278.0 9666.4 14023.0 12144.0 10154.0 10610.0 True False 12679.675021237206 16939.80295885793 15955.581662649112 12529.356841646604 11480.328395480597 9159.476967275337 12694.639922271865 11825.232867631596 10302.483040519288 12533.509011286214 1.0116620181801739 1.3515610786734922 1.27303388446774 0.9996687145127616 0.9159708095428626 0.7307990889883577 1.0128560095054429 0.9434893976605572 0.8219951037847482 1.0 13.613502762640925 -5.911049554383844 3.7331104535680426 0.9013850570678149 1.2252080636404001 0.6012685451355416 0.11162253884053235 0.14667667089657901 3.968618327597162 0.03228939931041862 0.04967053985678796 1.227299184422127e-06 5.911049554383844 0.3238230065725852 AIST(ph)GSLASSTLNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AISTGSLASSTLNK 14 0 Q12923-3;Q12923;Q12923-4 Q12923-3 PTPN13 Tyrosine-protein phosphatase non-receptor type 13 1 AIS(0.394)T(0.598)GS(0.008)LASSTLNK 84.31 0.017939 4794100.0 9499.5 10036.0 14569.0 15461.0 19967.0 15134.0 12683.0 13155.0 15962.0 10122.0 True False 11107.577726322652 11032.307754386642 14916.380213240182 14594.770295238315 16054.609684308803 14340.346398115631 11481.57442303174 12809.69518887464 16195.414052862814 11957.038474292092 0.9289572623023836 0.9226622276165086 1.24749788547647 1.2206007638611691 1.3426911453723749 1.1993225938803915 0.9602356342431605 1.07131002517185 1.3544670018151508 1.0 13.54557248584752 -5.251853121296121 24.436974620643916 1.1779476893255372 0.9258096850208317 0.3881315094022866 0.12484719010325544 520.8936063148864 1327834.8617707558 0.03333934002587683 0.08572311078693201 5.599469439316881e-06 5.251853121296121 -0.25213800430470545 AIST(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 1 AISTPEK 7 0 P42695 P42695 NCAPD3 Condensin-2 complex subunit D3 1 AIS(0.074)T(0.926)PEK 101.64 0.027219999999999998 19471000.0 89407.0 86118.0 110640.0 134080.0 121330.0 104930.0 100590.0 116020.0 110020.0 114140.0 True False 117836.5662188731 113953.95937072313 109172.84130910823 103169.92751535014 104485.42380824719 98368.71051235298 109542.31513134933 98091.77487437255 115835.43258971839 110143.99334151212 1.0698410566385532 1.0345907744364946 0.991182887028685 0.9366822863908864 0.948625709295649 0.8930919202044115 0.994537348865705 0.8905776147976541 1.0516727156474108 1.0 16.749031294825578 -5.274515731963718 1.9655571109884997 0.9531258282629214 1.0665595982337739 0.38321035922550395 0.0466766722601411 0.3503707091123431 2.434280087142841 0.012413193322131411 0.04901303681825583 5.314767468458682e-06 5.274515731963718 0.11343376997085253 AIST(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AISTPEK 7 0 P42695 P42695 NCAPD3 Condensin-2 complex subunit D3 1 AIS(0.011)T(0.989)PEK;AIS(0.078)T(0.922)PEK 98.03299999999999 0.012289 16080000.0 123289.0 117169.0 123402.0 140920.0 166267.0 149455.0 149015.0 153863.0 140162.0 113231.0 True False 144159.39263125393 128800.7639770557 126344.37168469117 133024.709268804 133688.17490764652 141617.3166995092 134899.22042482664 149824.25928132393 142211.60408954753 133758.88396389742 1.0777556477681414 0.9629324061332633 0.9445680760822774 0.9945112079785925 0.9994713692716666 1.058750734924888 1.0085253138119559 1.1201069778794108 1.0631937100187796 1.0 17.02927518968903 -6.706963788190904 3.7549937121221353 1.0555567623188729 0.9896926245531223 0.26009653680677025 0.04484894066952731 0.28250759154634025 8.116502089711862 0.015815860879439623 0.015284062275809019 1.963523990156458e-07 6.706963788190904 -0.06586413776575051 AIST(ph)PETPLTK ddPTM_PC-9_AZD4547_30min_R2 2 AISTPETPLTK 11 0 E9PIQ6;A0A3B3ITS5;Q14181 E9PIQ6 POLA2 DNA polymerase alpha subunit B 1 AIS(0.021)T(0.974)PET(0.005)PLTK;AIS(0.002)T(0.932)PET(0.052)PLT(0.013)K 164.9 0.00061701 26311400.0 121095.0 121389.0 158623.0 159554.0 148799.0 133369.0 135954.0 175800.0 133911.0 127236.0 True False 159600.69106752743 160625.6203587254 156519.55537757295 122771.29038472682 128140.82730770134 125029.41534663114 148053.64262220368 148634.14948211305 140989.26207527507 122781.50636762413 1.2998756554563011 1.30822324233253 1.27478119472596 0.9999167954262858 1.0436492522255811 1.0183082049203442 1.2058301531088194 1.2105581196982766 1.1482939592965613 1.0 16.90573374946927 -5.657732133084936 6.915721333455793 1.0986150239073464 1.300186385209473 0.6120133166291313 0.07462268479886217 0.16582447065128678 9.723452974504639 0.022598940686984457 0.03931934332842987 2.199215900934557e-06 5.657732133084936 0.2015713613021266 AIST(ph)PETPLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AISTPETPLTK 11 0 E9PIQ6;A0A3B3ITS5;Q14181 E9PIQ6 POLA2 DNA polymerase alpha subunit B 1 AIS(0.048)T(0.949)PET(0.002)PLTK;AIS(0.021)T(0.976)PET(0.003)PLTK 105.03 0.0063788000000000004 18369900.0 132164.0 158803.0 156248.0 147127.0 183193.0 133330.0 171975.0 148187.0 144215.0 124335.0 True False 154536.75484201376 174567.91234753537 159973.5448938397 138883.9511821698 147297.64671195383 126337.94008594954 155684.2830088213 144297.24826710508 146323.87154702484 146875.9512646819 1.0521583248405757 1.1885397905130868 1.0891745280039404 0.9455867348350998 1.0028710993436358 0.8601676380517783 1.0599712319702093 0.9824429869194188 0.9962411837138527 1.0 17.164238669980968 -5.648558778808602 4.995585451869739 0.9772669012108712 1.1242515884692392 0.5300405612553132 0.05716011340868872 0.14683863006986492 5.781822676747431 0.015164926238753536 0.026781192220908422 2.2461627525448973e-06 5.648558778808602 0.146984687258368 AIST(ph)PETPLTK ddPTM_PC-9_Lapatinib_30min_R1 4 AISTPETPLTK 11 0 E9PIQ6;A0A3B3ITS5;Q14181 E9PIQ6 POLA2 DNA polymerase alpha subunit B 1 AIS(0.039)T(0.96)PET(0.002)PLTK;AIS(0.021)T(0.933)PET(0.046)PLTK;AIS(0.002)T(0.97)PET(0.021)PLT(0.006)K;AIS(0.028)T(0.971)PET(0.001)PLTK 146.5 0.00025697 45953900.0 177585.0 264847.0 296062.0 268755.0 270184.0 277031.0 276385.0 309279.0 273040.0 251952.0 True False 175052.6053348999 264233.76304365066 271720.9251923695 288520.13924039743 254292.30832218155 265183.02992080234 290694.8629378089 323649.2314184994 242287.35996133473 295501.5674950626 0.5923914611309965 0.8941873482551513 0.9195244800077399 0.9763743105870942 0.8605447019377669 0.8973997402745864 0.9837337426058358 1.0952538565600234 0.8199190346609008 1.0 18.172806257669926 -4.69204955213341 2.5265463393408876 0.9451886553605396 0.45852313667167305 0.6706430783550219 0.07345608025860556 0.44581544732431766 2.876610060640536 0.01904576432666305 0.5173753859838437 2.0321251362869047e-05 4.69204955213341 -0.4866655186888666 AISTPET(ph)PLTK ddPTM_PC-9_AZD4547_30min_R2 2 AISTPETPLTK 11 0 E9PIQ6;A0A3B3ITS5;Q14181 E9PIQ6 POLA2 DNA polymerase alpha subunit B 1 AIS(0.053)T(0.458)PET(0.478)PLT(0.011)K;AIS(0.001)T(0.039)PET(0.954)PLT(0.006)K 122.46 0.0016312000000000002 10363500.0 60594.0 63377.0 93703.0 89000.0 95243.0 114401.0 92778.0 129249.0 111625.0 118075.0 True False 79861.63156650362 83862.37584521626 92460.43699554742 68482.42503629295 82020.15346384993 107247.48738514913 101035.06226519846 109276.53689655058 117525.26961304592 113941.23018923272 0.7009019600180728 0.7360143093587657 0.8114748001402989 0.6010328738996222 0.7198461288124719 0.9412526721629504 0.8867296069859892 0.9590605324785851 1.031455158223769 1.0 16.797930362187053 -6.771241775767044 5.3607872039149616 0.9582565112021235 0.7131089118530103 0.8162877496410541 0.05929311761623601 0.07812701423811755 6.682501201632036 0.0215793076916716 0.01998497911158211 1.6933948093856653e-07 6.771241775767044 -0.24514759934911323 AIT(ph)GASLADIMAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AITGASLADIMAK 13 0 C9JXB8;C9JNW5;P83731 C9JXB8 RPL24 60S ribosomal protein L24 1 AIT(0.965)GAS(0.035)LADIMAK;AIT(0.935)GAS(0.065)LADIMAK 114.7 0.0011485 19687600.0 146341.0 124573.0 116475.0 137811.0 153248.0 141420.0 123914.0 142196.0 114226.0 105426.0 True False 171113.64093349958 136939.78416572444 119252.20573389724 130089.89645929035 123220.15449997254 134003.6862443183 112175.96886032907 138463.50566911575 115896.33915563872 124538.8992482429 1.3739774637996394 1.09957438994834 0.9575498615592569 1.044572396613067 0.9894109811775218 1.0759986402096686 0.9007303704903409 1.1118092941637214 0.9306035291401042 1.0 16.926236907390624 -4.789493966590952 2.841576454909121 1.0057792046732859 1.4367496054379985 0.7709031058848488 0.06114152882906868 0.1717907244402536 1.9551466642049582 0.014204206934161705 0.17301909699221177 1.623700907489509e-05 4.789493966590952 0.4309704007647126 AIT(ph)PPLPESTVPFSNGVLK ddPTM_PC-9_AZD4547_30min_R2 1 AITPPLPESTVPFSNGVLK 19 0 Q92667-2;Q92667;I3NI36 Q92667-2 AKAP1 A-kinase anchor protein 1, mitochondrial 1 AIT(0.998)PPLPES(0.001)T(0.001)VPFSNGVLK 85.469 0.0031614 6591500.0 10332.0 16804.0 21936.0 21424.0 19469.0 14587.0 21520.0 18401.0 22680.0 16173.0 True False 13617.361081049541 22235.56437986987 21645.114307272226 16485.02779750045 16766.0654094022 13674.872584043607 23435.23831023598 15557.548262914435 23878.81849786233 15606.788192678074 0.8725280892476087 1.4247367302839213 1.3869038292854536 1.0562729239341124 1.074280319718057 0.8762131205483505 1.501605456607057 0.9968449671286793 1.5300277163410905 1.0 13.92988604721402 -12.406263062006193 14.476113361204753 1.1019488975617582 1.1798622302167805 0.0 0.2465540445491077 0.0 0.0 0.0 0.05376822154039794 3.924071734834116e-13 12.406263062006193 0.07791333265502232 AIT(ph)PPQQPYK ddPTM_PC-9_AZD4547_30min_R2 1 AITPPQQPYK 10 0 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 AIT(1)PPQQPYK 97.456 0.012563 36672000.0 41936.0 38457.0 54194.0 65257.0 57044.0 57977.0 46011.0 56385.0 41086.0 46490.0 True False 55270.77567701254 50887.47318237655 53475.35215026944 50213.00686059963 49124.42525111407 54351.68902482323 50105.889864882345 47671.993848401195 43257.72208126857 44862.39925045472 1.2320066826664944 1.1343011972740347 1.1919860070731152 1.1192670855670002 1.0950021860593235 1.21151989044082 1.1168794068537133 1.062626935805668 0.9642311335105448 1.0 15.453219157668093 -7.891941991154494 2.095277509899918 0.9832330970159987 1.1588353422872524 0.7488513802339206 0.04144027113599403 0.16390368042215686 1.3700947033588797 0.03157817391839736 0.011670516036854015 1.2825018753799523e-08 7.891941991154494 0.17560224527125368 AIT(ph)PPQQPYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AITPPQQPYK 10 0 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 AIT(1)PPQQPYK;AIT(1)PPQQPYK;AIT(1)PPQQPYK 115.57 0.0027206999999999995 71468000.0 195325.0 190912.0 203045.0 231909.0 261543.0 203451.0 214798.0 206624.0 193610.0 169167.0 True False 228389.66465540024 209864.48166654707 207886.36285245072 218915.89058912228 210295.52665213513 192781.67140498388 194450.77843714965 201200.33893622487 196441.1799758658 199835.63797476442 1.142887559846766 1.0501854613792616 1.0402867324330956 1.0954797292801564 1.0523424589496475 0.9647011582054682 0.9730535574525762 1.0068291170448425 0.9830137505336897 1.0 17.608454365598313 -6.629412506869111 4.712619150144671 0.985484653538425 1.0766169887656147 0.7223409882335434 0.028467767964700005 0.12075338720570271 4.502407635533103 0.009678627387270673 0.009653396482320591 2.3474021235747998e-07 6.629412506869111 0.09113233522718978 AIT(ph)PPQQPYK ddPTM_PC-9_Lapatinib_30min_R1 1 AITPPQQPYK 10 0 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 AIT(1)PPQQPYK 118.23 0.002177 34821000.0 103490.0 93859.0 106590.0 88730.0 96228.0 86043.0 78409.0 82508.0 93468.0 74294.0 True False 102014.21362225825 93641.67525217985 97826.5816492987 95255.500194603 90568.05823152709 82363.14146602948 82468.63436181648 86341.62289026247 82940.64957832573 87135.61890946783 1.1707521550773512 1.0746658648224177 1.1226933701009065 1.0931867058128268 1.0393919199176802 0.9452293160573422 0.9464399908319897 0.990887813397753 0.9518570088369879 1.0 16.41097495738277 -6.44078090953564 2.245127093499977 0.9649947897322322 1.1158995398111482 0.8552539129337942 0.028738904999700908 0.10718087597469772 1.068104520674992 0.009747291184364492 0.011069399783718879 3.624257868516435e-07 6.44078090953564 0.15090475007891602 AITGAS(ph)LADIMAK ddPTM_PC-9_AZD4547_30min_R2 1 AITGASLADIMAK 13 0 C9JXB8;C9JNW5;P83731 C9JXB8 RPL24 60S ribosomal protein L24 1 AIT(0.002)GAS(0.998)LADIMAK 92.19 0.019641 0.0 24103.0 20316.0 27479.0 36193.0 24027.0 30731.0 28536.0 24503.0 22760.0 31625.0 True False 31767.2526264554 26882.749698966683 27114.610505540368 27849.263026275843 20691.26578620918 28809.38571195202 31075.648718443037 20716.624372924955 23963.047134539072 30517.81837590084 1.0409411392113537 0.880887007316202 0.8884845624139405 0.912557466698462 0.6780060596516478 0.9440185191842572 1.01827884076349 0.6788370032795121 0.785214946867306 1.0 14.897364211618163 AITGASLADIMAK ddPTM_PC-9_Lapatinib_30min_R1 2 AITGASLADIMAK 13 0 C9JXB8;C9JNW5;P83731 C9JXB8 RPL24 60S ribosomal protein L24 0 ; 190.15 8.5226e-05 5104900.0 57641.0 54624.0 54881.0 65162.0 61115.0 53747.0 67103.0 54146.0 51999.0 49951.0 False True 56819.02876993516 54497.521484088546 50368.89602678637 69954.23085405985 57520.33585671299 51448.36610037641 70577.26500249933 56661.82082969121 46142.325046254955 58584.96379447625 0.9698568555792537 0.9302305225496599 0.8597580806482543 1.1940645913765258 0.9818276248919754 0.8781837995302691 1.2046993021979777 0.9671734376839136 0.7876137844537772 1.0 15.838242814799624 AITIAGVPQSVTECVK ddPTM_PC-9_Lapatinib_30min_R1 2 AITIAGVPQSVTECVK 16 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 0 ; 98.902 0.009155 13525200.0 56830.0 61543.0 71989.0 62262.0 67107.0 59252.0 74582.0 64075.0 61588.0 69843.0 False True 56019.5937786544 61400.50096469066 66070.34230557596 66840.95517994328 63159.89819743823 56717.930083158186 78443.49102747136 67052.15841728775 54651.310889608474 81915.26949005245 0.683872422411517 0.7495611178102387 0.8065693089564865 0.8159767476326285 0.771039375083887 0.6923975277899299 0.9576174444130628 0.8185550610369458 0.6671687858665369 1.0 16.321844783360298 -14.522878745280336 0.2667677070631084 2.4494426051515292 0.7638874703556566 0.3965956963265045 0.08200135901841683 223.32634363736167 2.174862067298642 178.5089887376083 0.10525119786389761 3.0000000000000132e-15 14.522878745280336 -1.6855551347958726 AITSLLGGGS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 AITSLLGGGSPK 12 0 A0A590UJS4;Q6KC79-2;Q6KC79 A0A590UJS4 NIPBL Nipped-B-like protein 1 AITSLLGGGS(1)PK;AITSLLGGGS(1)PK 169.79 0.00020622 343970000.0 138132.0 131449.0 113163.0 151689.0 131681.0 120588.0 129205.0 122829.0 107442.0 125164.0 True False 182055.10267591305 173937.31862470318 111662.38468060942 116719.44462168815 113399.36612951306 113047.61329708973 140703.99469674935 103848.60037962714 113121.16477280966 120782.04645695687 1.5073026829429659 1.440092494927955 0.9244948893990016 0.9663641910826829 0.9388760122550599 0.9359637182284085 1.164941303978419 0.8598016296787594 0.9365726785654578 1.0 16.882046496877358 -5.236894598085904 6.422699186158136 0.965662907377995 1.4796535645142086 0.8763169050737423 0.07633354168395001 0.055218350001509306 8.77723138554975 0.01967446454085506 0.05061599167327372 5.7956933902753715e-06 5.236894598085904 0.5139906571362136 AITSLLGGGS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AITSLLGGGSPK 12 0 A0A590UJS4;Q6KC79-2;Q6KC79 A0A590UJS4 NIPBL Nipped-B-like protein 1 AITSLLGGGS(1)PK;AITSLLGGGS(1)PK 162.41 0.0001249 318430000.0 224180.0 260490.0 160311.0 252930.0 229180.0 194064.0 233890.0 215390.0 189735.0 178823.0 True False 262129.24624317203 286349.72568156465 164133.42222285335 238759.1521101239 184273.82418239582 183886.94220985277 211734.24598303964 209736.24072456936 192509.5154316455 211242.1943379109 1.2408943538233668 1.3555517475050884 0.7769916551818212 1.1302626014582855 0.872334358956831 0.8705028973316777 1.002329324625087 0.9928709620818814 0.9113213202268675 1.0 17.688538507438537 -5.249762055729718 24.984169086397273 0.9477906953966239 1.2982230944757112 0.6902241068938886 0.09474760707349635 382.06834507467397 817449.0855034437 0.022790169120380243 0.05922788021065167 5.6264950906970954e-06 5.249762055729718 0.3504323990790873 AITSLLGGGS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 AITSLLGGGSPK 12 0 A0A590UJS4;Q6KC79-2;Q6KC79 A0A590UJS4 NIPBL Nipped-B-like protein 1 AITSLLGGGS(1)PK;AITSLLGGGS(1)PK 160.48 0.00025132 266490000.0 233876.0 214724.0 158656.0 174894.0 164815.0 176131.0 176689.0 176964.0 158531.0 126601.0 True False 230540.88535239478 214226.81977060286 145611.91610987062 187756.2881892809 155120.90573875737 168598.28771141433 185837.09187408345 185186.39347884397 140675.56937456192 148483.81416477138 1.5526331044848112 1.442762101550523 0.9806585110232027 1.2644899327608135 1.0446990913542997 1.1354657654761082 1.2515646430516758 1.2471823580268757 0.9474134953083525 1.0 17.17994614959148 -5.120117191799111 5.0167377322669875 1.127889137992272 1.5275000702205503 0.6559233762041674 0.11294512764418664 0.12482379968664056 4.489841408459926 0.027979290163929256 0.08035080455517744 7.583729049697624e-06 5.120117191799111 0.39961093222827837 AIVAIENPADVSVISSR ddPTM_PC-9_Lapatinib_30min_R1 2 AIVAIENPADVSVISSR 17 0 C9J9K3;A0A0C4DG17;P08865;F8WD59 C9J9K3 RPSA 40S ribosomal protein SA 0 ; 164.92 0.00012672 13746500.0 59141.0 56308.0 57240.0 63685.0 76483.0 65876.0 58492.0 57949.0 57667.0 58504.0 False True 58297.63849486889 56177.622285553196 52533.9481527897 68368.6073469322 71984.42031136344 63058.63704445644 61520.42955644591 60641.52209322525 51171.935199568936 68616.33844832011 0.8496174499135803 0.818720782191906 0.7656186462406004 0.9963896193386289 1.0490857125169988 0.9190032355333333 0.8965857250278862 0.8837767136015096 0.7457689576092754 1.0 16.066264521425893 -5.753965668466031 24.997714016061092 0.9258450550226213 0.8120591392847979 0.30460980096865287 0.08023438713216016 235.95744468793234 789209.9660286304 0.023577490528837338 0.039831031633291096 1.762115338376028e-06 5.753965668466031 -0.11378591573782337 AIYHDLEQSIR ddPTM_PC-9_AZD4547_30min_R2 1 AIYHDLEQSIR 11 0 A0A0U1RR22;Q9UNF0-2;Q9UNF0 A0A0U1RR22 PACSIN2 Protein kinase C and casein kinase substrate in neurons protein 2 0 108.35 0.0018434 3305300.0 11976.0 8277.6 14884.0 25106.0 23202.0 17426.0 15894.0 21160.0 12748.0 16032.0 False True 15784.118883725252 10953.172322709526 14686.628434967171 19318.199583833375 19980.80279567261 16336.34946524604 17308.53520924212 17890.20820842722 13421.833254442188 15470.724559761013 1.0202572492809658 0.7079934931553541 0.9493174271337455 1.2486939127647294 1.2915234007618626 1.0559524476142828 1.1187927974790017 1.156391101096792 0.8675633259835843 1.0 13.917253145456973 -5.557557424196209 7.626872535603535 1.1174340722187421 0.8551578128806154 0.3572949962956856 0.13342171491691518 0.18676049485173185 33.672609182779176 0.03605942156933707 0.06331210238875912 2.7697627855640313e-06 5.557557424196209 -0.2622762593381267 AIYHDLEQSIR ddPTM_PC-9_Lapatinib_30min_R1 1 AIYHDLEQSIR 11 0 A0A0U1RR22;Q9UNF0-2;Q9UNF0 A0A0U1RR22 PACSIN2 Protein kinase C and casein kinase substrate in neurons protein 2 0 112.94 0.0013643 2308300.0 15663.0 12600.0 18714.0 15838.0 16026.0 17946.0 14204.0 16465.0 14251.0 11229.0 False True 15439.642747757585 12570.825474141693 17175.407158129034 17002.779354019185 15083.382188328278 17178.491414169253 14939.413619294224 17230.02400843766 12645.902310317113 13169.917688298015 1.1723416283365469 0.9545105574434501 1.304139294157476 1.2910315581643168 1.1452905435946992 1.3043734836272372 1.1343589210560119 1.3082863853999032 0.9602111880739763 1.0 13.684958708359112 -8.27670994969584 24.568767466647223 0.9801055144503071 1.1992233824557237 0.4147052623538826 0.10531006937512166 738.9366158958002 1188857.9131363365 0.10058976634071434 0.026404023271838366 5.2879830001220185e-09 8.27670994969584 0.21911786800541655 AKADS(ph)PVNGLPK ddPTM_PC-9_AZD4547_30min_R2 1 AKADSPVNGLPK 12 1 Q96S94;Q96S94-3;A0A0A0MSF3 Q96S94 CCNL2 Cyclin-L2 1 AKADS(1)PVNGLPK 95.57 0.0021491999999999995 39957000.0 392950.0 336230.0 373400.0 455940.0 457850.0 456840.0 402240.0 402600.0 371550.0 414870.0 True False 517899.926132252 444909.77216398733 368448.4720247739 350830.0772027795 394285.4305662737 428273.7225813718 438038.58075786836 340387.4208276371 391189.3744656416 400345.5275766004 1.293632351202323 1.1113144559329697 0.9203261848710838 0.8763182127360051 0.9848628332455465 1.069760227306218 1.0941513032740349 0.8502341037455672 0.9771293733031479 1.0 18.610886163792337 -4.923285296880982 2.8867309105461954 0.9718671184407812 1.306005885575636 0.6551689807962651 0.0728748854847969 0.2049045036150492 2.9493567679690313 0.02056562854723243 0.13857629823878648 1.1932040069594915e-05 4.923285296880982 0.3341387671348548 AKADS(ph)PVNGLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AKADSPVNGLPK 12 1 Q96S94;Q96S94-3;A0A0A0MSF3 Q96S94 CCNL2 Cyclin-L2 1 AKADS(1)PVNGLPK;AKADS(1)PVNGLPK 74.33800000000001 0.0098822 43291000.0 277550.0 231834.0 212876.0 314090.0 297770.0 304260.0 319130.0 303830.0 263340.0 241673.0 True False 324533.7331376239 254848.94738246998 217951.7711767258 296492.55559351936 239424.10605983046 288304.0699808816 288899.6960988812 295854.7844344949 267190.84930966573 285486.4018175847 1.1367747502908703 0.8926833143713412 0.7634401140968842 1.0385522872748496 0.8386532757269947 1.009869710589919 1.0119560660667735 1.0363183064093373 0.9359144519968795 1.0 18.123062503746304 AKEAAEQDVEK ddPTM_PC-9_AZD4547_30min_R2 2 AKEAAEQDVEK 11 1 P26373;P26373-2;J3KS98 P26373 RPL13 60S ribosomal protein L13 0 ; 97.463 0.0069738 10137800.0 58297.0 54299.0 79079.0 106139.0 84669.0 78227.0 63673.0 74300.0 63569.0 73150.0 False True 76834.23334707176 71850.08987518176 78030.36079069931 81670.29338120333 72914.17084332413 73335.4533236429 69339.77364905464 62818.64224414669 66929.12756131437 70589.040765127 1.088472552031477 1.0178646585416946 1.1054174974601514 1.156982620757623 1.0329389669132012 1.0389070672833494 0.982302251135143 0.8899206103843372 0.94815182124389 1.0 16.107156596174974 -7.143000909648156 1.6954545044403473 0.939398898841095 1.0840133487058092 0.6536095374760402 0.04357280557955229 0.22816203060281806 1.2943309550584068 0.023103128665159452 0.015597209999959437 7.194474710889726e-08 7.143000909648156 0.14461444986471428 AKEAAEQDVEK ddPTM_PC-9_Lapatinib_30min_R1 2 AKEAAEQDVEK 11 1 P26373;P26373-2;J3KS98 P26373 RPL13 60S ribosomal protein L13 0 ; 165.35 0.00038621 15778200.0 139328.0 112536.0 112579.0 103141.0 115556.0 103026.0 101049.0 92484.0 107916.0 81912.0 False True 137341.15717037392 112275.42980619143 103323.18918750697 110726.3332082896 108759.22327183721 98619.81814533613 106280.82278344582 96781.14426944117 95761.36367414088 96070.38005912065 1.42958898555263 1.1686789386811873 1.075494747953771 1.1525543371448081 1.1320786199129012 1.02653719163645 1.1062808611565997 1.0073983699229994 0.996783437467515 1.0 16.551804074558014 -1.5228787452803378 0.7288864238490852 1.0504024720336747 56.86494488092107 0.8338665995039118 0.05016762061938198 137.43869661585978 0.6484952342153316 0.020192594830557863 12558.834624432151 0.02999999999999998 1.5228787452803378 55.8145424088874 AKEAQDDLVK ddPTM_PC-9_AZD4547_30min_R2 2 AKEAQDDLVK 10 1 P15311;E7EQR4 P15311 EZR Ezrin 0 ; 85.958 0.015000999999999999 7382200.0 58585.0 38420.0 61670.0 70072.0 76609.0 68480.0 49386.0 71805.0 62211.0 74730.0 False True 77213.81135629972 50838.51365595094 60852.21550553781 53917.983001608 65973.16271759696 64197.93477447765 53781.25832664095 60709.18716475037 65499.34645372633 72113.72544604167 1.0707228184192776 0.7049769422048555 0.8438368026218508 0.7476798996045705 0.9148489044150226 0.8902318439020749 0.7457839404910818 0.8418534306645324 0.9082785010564391 1.0 16.13798625411112 -8.54527173774716 2.693032423083966 0.9992837968579601 0.8377562865768755 0.1898027943660774 0.0986331950555071 0.42427830594572796 7.554184238345983 0.0896007283045213 0.02412751283063521 2.849234945379954e-09 8.54527173774716 -0.16152751028108459 AKEFTNVYIK ddPTM_PC-9_Lapatinib_30min_R1 2 AKEFTNVYIK 10 1 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YAR2;H0YBN4;Q13310-3;Q13310-2;Q13310;B1ANR0;H0Y5F5;H0YCC8 A0A087WTT1 PABPC1;PABPC4 Polyadenylate-binding protein;Polyadenylate-binding protein 1;Polyadenylate-binding protein 4 0 ; 86.014 0.024544999999999997 3589700.0 62813.0 52312.0 56496.0 53218.0 54916.0 55981.0 49352.0 43689.0 62897.0 43973.0 False True 61917.27510150658 52190.874778039695 51851.116960866646 57131.82925004377 51685.94884901007 53586.823128084754 51907.205078809435 45718.950434535844 55812.87752522742 51573.67445966055 1.2005596993081518 1.0119673520424048 1.0053795372176382 1.1077711613263206 1.0021769709163797 1.039034423851239 1.006467071090887 0.8864784391171487 1.0821970338546008 1.0 15.65434721616437 -4.760920234803823 24.979911656044383 1.0147413499467743 1.200559911437009 0.49963849973424845 0.05548451787781778 10.526263448481233 506011.69764183776 0.013779628386778169 0.07910067469809977 1.7341224681073492e-05 4.760920234803823 0.18581856149023457 AKEGTSDPPS(ph)PLLLPSPGGWK ddPTM_PC-9_AZD4547_30min_R2 1 AKEGTSDPPSPLLLPSPGGWK 21 1 Q8NC74 Q8NC74 RBBP8NL RBBP8 N-terminal-like protein 1 AKEGTSDPPS(1)PLLLPSPGGWK 100.81 8.895700000000001e-05 6250000.0 33025.0 32625.0 39184.0 50617.0 40022.0 44140.0 35817.0 40392.0 31120.0 39839.0 True False 43526.26303732686 43170.39323335244 38664.39455762924 38948.03267485435 34465.636130006416 41379.918822217354 39004.64361327706 34150.344515821955 32764.939667260827 38444.24873604783 1.1321917963899188 1.122935020261511 1.0057263655506157 1.01310427321042 0.8965095498846148 1.0763617493562008 1.0145768195673899 0.888308281176018 0.8522715554209357 1.0 15.230480166537808 -3.7181006711573685 0.41464800292325005 0.9359356079574829 1.6069543926910228 0.505676078648907 0.06437880135508366 11.143332700498705 0.758794742229965 0.050044251226150895 4.432768356158897 0.00019138122444455332 3.7181006711573685 0.6710187847335399 AKEGTSDPPS(ph)PLLLPSPGGWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AKEGTSDPPSPLLLPSPGGWK 21 1 Q8NC74 Q8NC74 RBBP8NL RBBP8 N-terminal-like protein 1 AKEGT(0.001)S(0.001)DPPS(0.998)PLLLPSPGGWK;AKEGT(0.01)S(0.01)DPPS(0.976)PLLLPS(0.004)PGGWK;AKEGTSDPPS(1)PLLLPSPGGWK 90.397 0.00029951 9316700.0 82624.0 61671.0 70783.0 102290.0 98375.0 107392.0 86921.0 89995.0 87204.0 81538.0 True False 96610.61130161419 67793.28931055988 72470.73516602223 96559.02292865435 79099.12494084638 101760.1744671888 78687.21362645602 87632.72660758461 88479.19352624049 96320.19394554735 1.0030151242867205 0.7038325665009088 0.7523939913056247 1.002479531792077 0.8212101917648074 1.0564780893684333 0.8169337124771596 0.909806376190708 0.918594428664257 1.0 16.5555506765889 -5.754612305953132 24.996817007347346 0.9242056414626039 0.8081557645864027 0.1986981328141374 0.10182566003570018 243.7146494478156 892332.1476187442 0.026557053038832112 0.0447249403733821 1.7594936104524517e-06 5.754612305953132 -0.11604987687620116 AKEGTSDPPS(ph)PLLLPSPGGWK ddPTM_PC-9_Lapatinib_30min_R1 1 AKEGTSDPPSPLLLPSPGGWK 21 1 Q8NC74 Q8NC74 RBBP8NL RBBP8 N-terminal-like protein 1 AKEGT(0.006)S(0.006)DPPS(0.988)PLLLPSPGGWK 65.118 0.0020805999999999997 2481300.0 43903.0 32526.0 36231.0 31293.0 28834.0 33463.0 27921.0 28523.0 33609.0 25460.0 True False 43276.93516917585 32450.688045391475 33252.22703570447 33594.391610387815 27138.040809825117 32031.86549606295 29366.61276149775 29848.282708330855 29823.600501540077 29860.72707668247 1.449292746892616 1.0867346920943344 1.1135772732630593 1.125035955223638 0.9088204965717853 1.0727088263391908 0.9834527031469852 0.9995832530025255 0.998756675447083 1.0 14.865961673526714 -1.522878745372753 0.8510339913664667 1.0083881437221087 151.22632612478165 0.8221449719801566 0.05924312846056289 261.7371865633105 0.7266074082277326 0.019948223151259662 76123.5179274979 0.029999999993616164 1.522878745372753 150.21793798105955 AKFENLCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AKFENLCK 8 1 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 0 106.42 0.0049599 8972400.0 41574.0 27255.0 37239.0 42302.0 36996.0 37209.0 41334.0 41647.0 35313.0 37840.0 False True 48611.657076071184 29960.696277980063 38126.91898969393 39931.95608493441 29746.899378008133 35257.69453729912 37418.54428775476 40553.81037864402 35829.385819367504 44700.09245872482 1.0875068574177609 0.6702602753147586 0.852949443558748 0.8933305031036969 0.6654773567968753 0.7887611098311569 0.837102167569481 0.9072422034941113 0.8015505975172568 1.0 15.447990195065556 -11.02691343785155 6.619686490740604 1.0000899896365025 0.8272842530443698 0.15622614983903893 0.11498283920165885 0.0001451335489086953 1.0873799650202443e-05 0.10580767888613514 0.025648816143038152 9.399106317931966e-12 11.02691343785155 -0.17280573659213272 AKFENLCK ddPTM_PC-9_Lapatinib_30min_R1 1 AKFENLCK 8 1 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 0 76.679 0.031908 20895000.0 69743.0 67404.0 77266.0 70160.0 81375.0 61542.0 65695.0 51263.0 68774.0 50955.0 False True 68748.4520307003 67247.93017928944 70913.48773538509 75319.8004468988 76588.68248940549 58909.99212140891 69096.36565189621 53644.86612478224 61027.94789767381 59762.503856730356 1.150360972082296 1.1252528900145151 1.1865882979968037 1.2603186879094659 1.2815507642218742 0.9857350063952276 1.1561825759098392 0.8976341796753692 1.021174548576096 1.0 15.866952973225713 -6.771799219307108 24.99918934432752 1.0147496999763195 1.1991319312193924 0.625063181729753 0.0730416132880358 150.84343856202491 363996.0642202825 0.026788242736891735 0.02388247357882878 1.6912226278986979e-07 6.771799219307108 0.18438223124307296 AKGSET(ph)PGATPGSK ddPTM_PC-9_AZD4547_30min_R2 2 AKGSETPGATPGSK 14 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 AKGS(0.022)ET(0.938)PGAT(0.038)PGS(0.002)K;AKGS(0.01)ET(0.502)PGAT(0.02)PGS(0.468)K 102.03 0.016105 51507300.0 208958.0 167176.0 246318.0 386546.0 335474.0 231807.0 202491.0 248242.0 189869.0 264837.0 True False 275402.2974035964 221212.3726951397 243051.6623786782 297433.791776167 288899.22580275265 217312.07164525913 220512.3067229556 209881.90293366677 199905.08771475413 255565.1372401088 1.0776207599272438 0.8655811785756444 0.9510360646347709 1.163827723093239 1.1304328474635639 0.8503197031960188 0.8628418926943845 0.8212462200447878 0.7822079720010445 1.0 17.96333151979362 -6.78321153077672 24.761792240832367 0.8521208730646513 1.0303300254111813 0.4512873446717578 0.09556978220147014 212.40485896184865 241569.4058344993 0.03594194750581882 0.03172616595831005 1.647359820472377e-07 6.78321153077672 0.17820915234653 AKGSET(ph)PGATPGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AKGSETPGATPGSK 14 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 AKGS(0.133)ET(0.498)PGAT(0.231)PGS(0.137)K 62.556000000000004 0.034473000000000004 35633000.0 242660.0 148380.0 177480.0 266560.0 274310.0 298700.0 280120.0 274740.0 277440.0 227850.0 True False 283737.5452465338 163110.1857907424 181711.79629664833 251625.5073991795 220560.92465081118 283035.64616870263 253585.00570682413 267528.36611109227 281497.0351350866 269157.4013403923 1.0541695819380519 0.6060029743877028 0.6751135038149848 0.9348637865653899 0.8194495992026496 1.051561817580335 0.9421439070372268 0.9939476483976012 1.0458454188264692 1.0 18.03809057183676 -6.4464485401915335 1.4644106621522737 1.0037080382810888 0.7766715196598457 0.3487798231691547 0.12286528250889382 0.4264764754353924 1.8577261884473766 0.04851912603083963 0.05726343068258544 3.577267853224163e-07 6.4464485401915335 -0.22703651862124308 AKGSETPGAT(ph)PGSK ddPTM_PC-9_Lapatinib_30min_R1 1 AKGSETPGATPGSK 14 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 AKGS(0.001)ET(0.029)PGAT(0.969)PGS(0.001)K 166.52 0.004469600000000001 5382300.0 42139.0 22874.0 23087.0 22241.0 21496.0 24782.0 17543.0 19380.0 26229.0 16230.0 True False 41538.09013265383 22821.03665837438 21188.875978397187 23876.677333801017 20231.64754276204 23722.131629663578 18451.290701441747 20280.46555016836 23274.81381638534 19035.333874884374 2.1821571612915114 1.198877666573789 1.1131339286018116 1.2543345701597814 1.0628470020930973 1.2462156842419803 0.9693179443406965 1.0654116015756803 1.222716342637658 1.0 14.216392254173327 -4.760230089130043 4.685996282833655 1.1231324481485419 2.2641094341824215 0.919681743424716 0.09390922608305526 0.04757635487785868 2.4531257512558895 0.022768431243309382 0.1823247336462899 1.7368803860630117e-05 4.760230089130043 1.1409769860338796 up AKNS(ph)PPQAPSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AKNSPPQAPSTR 12 1 Q8N1F8 Q8N1F8 STK11IP Serine/threonine-protein kinase 11-interacting protein 1 AKNS(1)PPQAPSTR 55.975 0.03703 23252000.0 44624.0 45382.0 48394.0 52791.0 57223.0 42851.0 51304.0 54120.0 47054.0 42577.0 True False 52177.96183582525 49887.22504081057 49547.896495267036 49833.29142073121 46010.563928742595 40603.81812512577 46444.11371120556 52699.40734487994 47742.075732577774 50295.87306065344 1.0374203420805945 0.9918751182756075 0.9851284703919069 0.9908027913271457 0.9147979969103419 0.8072992007944727 0.9234179841196332 1.0477879026242969 0.9492245153991868 1.0 15.618152406634096 -6.152373226356263 5.179794849476061 0.9354854735049094 1.0009720121932908 0.19827897209022127 0.059719116269204744 0.4163873454235557 16.496926741832308 0.019728004637460873 0.025739825868853018 7.040877261496756e-07 6.152373226356263 0.06548653868838139 AKNS(ph)PPQAPSTR ddPTM_PC-9_Lapatinib_30min_R1 3 AKNSPPQAPSTR 12 1 Q8N1F8 Q8N1F8 STK11IP Serine/threonine-protein kinase 11-interacting protein 1 AKNS(0.999)PPQAPS(0.001)TR;AKNS(1)PPQAPSTR;AKNS(0.988)PPQAPS(0.006)T(0.006)R 144.55 0.00047576 13844200.0 81036.0 66764.0 64743.0 62104.0 66268.0 66705.0 54340.0 57144.0 72111.0 50880.0 True False 79880.41177981763 66609.41205996806 59420.080455207266 66671.33533287089 62370.24652790076 63852.18264694982 57153.459312338 59799.118854428285 63989.09981750597 59674.54020666159 1.3386012108879293 1.1162115674337834 0.9957358741169501 1.1172492507186211 1.0451734745153216 1.0700071156949085 0.9577528224667885 1.0020876348160415 1.072301514111419 1.0 15.864827924909711 -4.786688218359294 2.6771790922587653 1.0347949333689828 1.3973482240130066 0.8128924071958656 0.044269249160163095 0.19166489212482352 1.8444217469253277 0.011737535298818295 0.1569969424712862 1.6342247429516156e-05 4.786688218359294 0.36255329064402386 AKPAMPQDSVPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 AKPAMPQDSVPSPR 14 1 P53396 P53396 ACLY ATP-citrate synthase 1 AKPAMPQDSVPS(1)PR;AKPAMPQDS(0.002)VPS(0.998)PR;AKPAMPQDSVPS(1)PR;AKPAMPQDS(0.001)VPS(0.999)PR 127.03 6.527800000000001e-05 36938100.0 75055.0 78896.0 97186.0 142261.0 115568.0 115503.0 85956.0 109371.0 82714.0 95671.0 True False 98920.928759018 104397.5891046306 95897.25013979561 109464.92436054014 99523.37804888761 108280.5791509421 93605.9174811639 92470.22504555272 87086.09317602229 92321.58740998601 1.0714821043936922 1.1308036617808241 1.0387305161243667 1.1856915314337393 1.0780076560741916 1.1728630560703495 1.0139114816719341 1.0016099986984262 0.943290682267911 1.0 16.494380409954267 -7.4312686402305035 5.134640557485965 0.984028624182057 1.111846947990439 0.6500503889827319 0.04469364595199333 0.1350497240992062 5.7290719006581945 0.018396443759004958 0.012067367634188642 3.704515018254598e-08 7.4312686402305035 0.12781832380838187 AKPAMPQDSVPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AKPAMPQDSVPSPR 14 1 P53396 P53396 ACLY ATP-citrate synthase 1 AKPAMPQDSVPS(1)PR;AKPAMPQDS(0.007)VPS(0.993)PR;AKPAMPQDSVPS(1)PR;AKPAMPQDS(0.001)VPS(0.999)PR 136.49 3.0186e-05 43712500.0 151031.0 135557.0 141043.0 173572.0 196641.0 156072.0 175304.0 141552.0 136342.0 139744.0 True False 176597.56530177724 149014.20309499739 144406.00002855604 163847.32356801673 158110.60764922926 147887.30957094647 158697.9360289483 137836.4099867417 138335.7438162775 165078.4809871047 1.0697794421525624 0.9026870262189886 0.8747718004494873 0.992541987231006 0.9577905412249357 0.895860615427512 0.9613484148872509 0.834975032254561 0.8379998591523493 1.0 17.332792542619053 -7.747075892191039 24.992737620283346 0.8773655754684947 0.9456919852175697 0.12863172810001577 0.06762559499120079 390.99782261895956 680345.817426958 0.031190107595416555 0.017900505789830705 1.790292976173905e-08 7.747075892191039 0.068326409749075 AKPAMPQDSVPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 AKPAMPQDSVPSPR 14 1 P53396 P53396 ACLY ATP-citrate synthase 1 AKPAMPQDSVPS(1)PR;AKPAMPQDSVPS(1)PR;AKPAMPQDSVPS(1)PR;AKPAMPQDS(0.001)VPS(0.999)PR 103.71 0.00054121 235642000.0 195653.0 162819.0 190117.0 154577.0 161054.0 175293.0 162696.0 166558.0 170799.0 138191.0 True False 192862.95234163446 162442.0026090692 174486.31413284285 165945.10823375543 151581.12036434677 167796.12701794127 171119.602802358 174296.89272987287 151561.81802679464 162077.13022206735 1.1899455035845365 1.0022512268479946 1.076563447870611 1.0238650450337343 0.9352406484286855 1.035285649419126 1.055791169105112 1.0753947363891674 0.9351215548987983 1.0 17.306321009197845 AKPPADPAAAAS(ph)PCR ddPTM_PC-9_AZD4547_30min_R2 1 AKPPADPAAAASPCR 15 1 Q9GZT9-2;Q9GZT9 Q9GZT9-2 EGLN1 Egl nine homolog 1 1 AKPPADPAAAAS(1)PCR 77.554 0.0060405 35423000.0 39584.0 40533.0 66655.0 75964.0 62702.0 64315.0 57820.0 68014.0 43153.0 50802.0 True False 52170.88860165171 53634.49958398391 65771.11114839675 58451.6734321006 53996.90961530315 60293.37288289333 62965.867987818034 57503.99910623673 45433.97948140444 49023.43744292534 1.064202987854345 1.0940583194808997 1.3416258544694994 1.192320989325808 1.1014509065825522 1.229888723186513 1.284403364434102 1.1729899432936488 0.9267807777514611 1.0 15.581184026707952 -8.236011200314906 8.557237313569036 0.963343817090971 1.189725245445392 0.5310858404312179 0.08325259488341481 0.20304049742053856 65.13331837169527 0.06131363153640042 0.02219847328318607 5.807494399870437e-09 8.236011200314906 0.22638142835442088 AKPPADPAAAAS(ph)PCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AKPPADPAAAASPCR 15 1 Q9GZT9-2;Q9GZT9 Q9GZT9-2 EGLN1 Egl nine homolog 1 1 AKPPADPAAAAS(1)PCR;AKPPADPAAAAS(1)PCR;AKPPADPAAAAS(1)PCR 95.307 0.0013513 46793200.0 239837.0 240162.0 298750.0 278082.0 318012.0 252224.0 268066.0 207650.0 226672.0 176748.0 True False 280436.6671033263 264003.69618463627 305873.33301568474 262501.96709400765 255699.83146824347 238996.92942502434 242672.84785022645 202199.40752336165 229986.64917870626 208791.0132636023 1.3431452950001737 1.2644399395261663 1.464973651090597 1.2572474408301966 1.2246687607450708 1.1446705760428804 1.1622763070930056 0.9684296482056024 1.1015160355026588 1.0 17.671700091521565 -6.846592001439269 0.8374696346046784 1.0228006095614346 1.3525901332207784 0.7853367690625855 0.06651105558566825 0.27146782265732966 0.40964962317185866 0.04425061516427035 0.03828868344621769 1.4236656237468923e-07 6.846592001439269 0.3297895236593438 AKPPADPAAAAS(ph)PCR ddPTM_PC-9_Lapatinib_30min_R1 4 AKPPADPAAAASPCR 15 1 Q9GZT9-2;Q9GZT9 Q9GZT9-2 EGLN1 Egl nine homolog 1 1 AKPPADPAAAAS(1)PCR;AKPPADPAAAAS(1)PCR;AKPPADPAAAAS(1)PCR;AKPPADPAAAAS(1)PCR 80.541 0.0045959 80334100.0 399042.0 406037.0 445148.0 373121.0 363877.0 331068.0 295866.0 320664.0 330600.0 251073.0 True False 393351.58790465887 405096.8462733383 408549.6497609718 400561.56303516746 342474.47026970715 316908.99339720164 311184.49379654374 335563.22008148575 293364.34662766405 294470.6335162567 1.3357922425325421 1.3756782516344683 1.3874037111358242 1.3602767727704632 1.1630173989855608 1.0761989730962636 1.056759005408138 1.1395473160584635 0.9962431333970979 1.0 18.167764240944358 -6.406983017535523 2.3541564965120068 1.0618700640418846 1.3717229355876064 0.9297207491648354 0.04031866163563673 0.07232291218101689 0.7868646546428415 0.013623195938795954 0.015758466236557418 3.917571959130274e-07 6.406983017535523 0.30985287154572183 AKPS(ph)PAPPSTTTAPDASGPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AKPSPAPPSTTTAPDASGPQK 21 1 Q5QNY5;P40855;E9PS71;B7Z8B3 Q5QNY5 PEX19 Peroxisomal biogenesis factor 19 1 AKPS(0.974)PAPPS(0.023)T(0.003)TTAPDASGPQK 79.388 0.0034325000000000002 0.0 11689.0 14155.0 13268.0 11748.0 14767.0 9673.9 16056.0 10232.0 10155.0 8141.1 True False 13667.716831726455 15560.21485286398 13584.359439170199 11089.79764752989 11873.512355796469 9166.583654072349 14535.059444626471 9963.42084170014 10303.497663627482 9617.016985087854 1.4212012782050418 1.6179876646772744 1.412533580863391 1.1531431903183418 1.234635685286564 0.9531628849450982 1.5113895989956692 1.036019886119513 1.0713818723211246 1.0 13.231373751610011 -5.666661190934346 3.343363017992111 1.148610096341537 1.5206999255272302 0.5200050954103671 0.15439150840338547 0.18742987081212872 4.111314506700159 0.04236146630311373 0.07802868573460044 2.1544618540473794e-06 5.666661190934346 0.3720898291856931 AKS(ph)ESLELPQAAPPQIYHEK ddPTM_PC-9_AZD4547_30min_R2 1 AKSESLELPQAAPPQIYHEK 20 1 B0QY58;B0QY55;B0QY57;B0QY56;H0YGT9;Q15040 B0QY58 JOSD1 Josephin-1 1 AKS(0.792)ES(0.208)LELPQAAPPQIYHEK 81.97399999999999 0.00048706 10604000.0 112800.0 94416.0 124210.0 167480.0 164730.0 135760.0 116710.0 148020.0 118460.0 129760.0 True False 148668.053614246 124934.12559448884 122562.89424262784 128870.07354020588 141860.08294677804 127270.90573865503 127096.9639027712 125146.91016121907 124721.55375911677 125217.1418958699 1.187281959668731 0.9977397958690318 0.9788028411042209 1.0291727760994076 1.1329126411841306 1.0164016189132716 1.015012497318175 0.9994391204463903 0.9960421701913204 1.0 16.9340725513664 -4.756575016338814 24.99946472444621 1.0208847416069367 1.187282213473752 0.6083176492554669 0.04061199956204017 112.92855030433053 580307.0064458468 0.01093312170511068 0.08723529805882023 1.751559858509338e-05 4.756575016338814 0.1663974718668153 AKS(ph)ESLELPQAAPPQIYHEK ddPTM_PC-9_Lapatinib_30min_R1 1 AKSESLELPQAAPPQIYHEK 20 1 B0QY58;B0QY55;B0QY57;B0QY56;H0YGT9;Q15040 B0QY58 JOSD1 Josephin-1 1 AKS(0.641)ES(0.359)LELPQAAPPQIYHEK 74.819 0.0010293 9967900.0 131980.0 105440.0 106470.0 105520.0 99703.0 103530.0 77737.0 88206.0 122220.0 91683.0 True False 130097.94099783227 105195.86015821408 97716.44758608543 113280.29280440109 93838.66556363992 99102.26324021743 81761.84148993771 92304.37277183433 108454.29656634324 107530.28439008172 1.2098725650709068 0.9782905416357016 0.9087342058131719 1.0534733860970773 0.8726719741875371 0.9216218835682567 0.7603610643615035 0.8584035027470662 1.0085930413139197 1.0 16.714383506217246 -1.5228874108892776 0.8998346246817638 0.9048797585760667 149.77751883743028 0.5242040718699057 0.08082378421877447 714.4364744361678 1.5850433424173132 0.027742594485176866 218397.6137657539 0.029999401406912964 1.5228874108892776 148.8726390788542 AKS(ph)IVFHR ddPTM_PC-9_Lapatinib_30min_R1 1 AKSIVFHR 8 1 F5H018;B5MDF5;J3KQE5;P62826;B4DV51 F5H018 RAN GTP-binding nuclear protein Ran 1 AKS(1)IVFHR 57.148999999999994 0.039032 12808000.0 77749.0 64873.0 85221.0 57314.0 58393.0 72363.0 65642.0 62745.0 71872.0 53510.0 True False 76640.28500257962 64722.79055428524 78214.45834257334 61529.06275389922 54958.43854505507 69268.2031763919 69040.6215712272 65660.36176188408 63777.01851428747 62759.13220240685 1.2211814012246718 1.0312888066320822 1.2462641785791577 0.980400152052127 0.8757042460021042 1.1037151207411917 1.1000888499949566 1.046228006310227 1.0162189354148141 1.0 15.937537783226718 -5.776313582328742 24.999830352392014 1.0205334146242364 1.1527492197919027 0.4132638176362713 0.0806942127800979 256.4153426146607 430969.9590897275 0.02346932710514791 0.03497161156568967 1.673733920046049e-06 5.776313582328742 0.1322158051676663 AKS(ph)LESLIYMSTR ddPTM_PC-9_Lapatinib_30min_R1 1 AKSLESLIYMSTR 13 1 O95171-2;O95171;O95171-3;F2Z2X8 O95171-2 SCEL Sciellin 1 AKS(0.892)LES(0.106)LIY(0.002)MSTR 59.606 0.028658999999999997 6220100.0 11054.0 12168.0 11865.0 10154.0 12597.0 13366.0 9747.9 10366.0 10905.0 8375.0 True False 10896.36793294467 12139.825743599698 10889.505500224492 10900.759032751026 11856.069226654887 12794.367337667794 10252.598565158987 10847.642202943503 9676.764065259144 9822.607591013963 1.1093152029113957 1.2359066196134723 1.1086165663572431 1.1097622430446463 1.2070185148698398 1.3025428552569374 1.0437756441108768 1.1043546331696357 0.9851522597840271 1.0 13.261890349857852 -7.385153391155606 13.10327790838041 1.041669686350827 1.1763921328391256 0.5414655966347147 0.06541148896969555 0.6433726989149086 65.60284987024994 0.028003544161484338 0.018875802927344074 4.119519935254301e-08 7.385153391155606 0.13472244648829856 AKS(ph)PNGSSSVNWPPEFRPGEPWK ddPTM_PC-9_AZD4547_30min_R2 1 AKSPNGSSSVNWPPEFRPGEPWK 23 2 Q8NDV7-2;Q8NDV7-6;Q8NDV7-5;Q8NDV7;H7C269 Q8NDV7-2 TNRC6A Trinucleotide repeat-containing gene 6A protein 1 AKS(0.93)PNGS(0.023)S(0.023)S(0.023)VNWPPEFRPGEPWK 50.232 0.010169 5485100.0 29118.0 25494.0 29793.0 42254.0 43764.0 34819.0 28582.0 30869.0 32039.0 37200.0 True False 38376.91830797528 33734.436937657854 29397.925353599607 32512.99311779237 37688.124021628144 32641.762425708814 31125.742629329223 26098.905349051965 33732.51613108513 35897.63932279877 1.0690652374904748 0.9397397036142414 0.8189375654829992 0.9057139614510308 1.049877505390507 0.9093010861295792 0.8670693454084906 0.7270368147154573 0.9396861957343652 1.0 15.131601353144521 -7.097659426273462 4.411500984396948 0.8618154626510646 0.9479196700454272 0.09899242546274778 0.09337324542488408 0.46135655269741305 15.250664408804967 0.03722365886607906 0.028790631639743443 7.986207201257906e-08 7.097659426273462 0.08610420739436264 AKS(ph)PQPPVEEEDEHFDDTVVCLDTYNCDLHFK ddPTM_PC-9_AZD4547_30min_R2 3 AKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK 32 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1W2PRI6 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 1 AKS(0.818)PQPPVEEEDEHFDDT(0.182)VVCLDTYNCDLHFK;AKS(0.962)PQPPVEEEDEHFDDT(0.038)VVCLDTYNCDLHFK;AKS(0.96)PQPPVEEEDEHFDDT(0.039)VVCLDTYNCDLHFK 75.018 2.6579999999999996e-07 39145000.0 71906.0 60691.0 96619.0 118570.0 95006.0 101575.0 95008.0 134758.0 89075.0 107414.0 True False 94770.61226228674 80308.17887280887 95337.76893026696 91235.51838823878 81816.05682293212 95223.49919272176 103463.52794511607 113934.24753077688 93783.32264978337 103653.46855427693 0.9143023729366202 0.7747756056108863 0.9197740341930232 0.8801974469427848 0.789322904135042 0.9186716134140662 0.9981675421786643 1.0991841288081599 0.9047774662810711 1.0 16.66140886857182 -7.112208246202156 3.395420063868961 1.0088047809636396 0.8558742861951043 0.5423549953596284 0.06223527327143868 0.1818223497255992 3.8917916432459045 0.024324590249449676 0.018537965161697038 7.723101700151977e-08 7.112208246202156 -0.15293049476853526 AKS(ph)PQPPVEEEDEHFDDTVVCLDTYNCDLHFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK 32 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1W2PRI6 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 1 AKS(0.98)PQPPVEEEDEHFDDT(0.019)VVCLDT(0.001)YNCDLHFK;AKS(0.998)PQPPVEEEDEHFDDT(0.002)VVCLDTYNCDLHFK;AKS(0.99)PQPPVEEEDEHFDDT(0.01)VVCLDTYNCDLHFK;AKS(0.998)PQPPVEEEDEHFDDT(0.002)VVCLDTYNCDLHFK 96.46600000000001 3.1351e-13 66089200.0 142993.0 118506.8 125674.0 158335.0 193511.0 152166.0 170702.0 167082.0 145784.0 123441.0 True False 167198.890659514 130271.37191984324 128670.54478129932 149464.0032789963 155593.90868033626 144186.1470870665 154531.87078454345 162696.2745380121 147915.81520376852 145819.8761415814 1.1466124857846882 0.8933718459159739 0.8823937325002854 1.0249906064511858 1.067028122622083 0.9887962526252 1.059744904971002 1.1157345544584392 1.0143734799236293 1.0 17.153827855668872 -5.980728185029468 24.94928570810138 1.0451512097995732 0.9639908329075506 0.13079212415634944 0.0753864454764327 393.3144200636793 509180.84518166323 0.02113929709055046 0.031349591763635824 1.0453742903437979e-06 5.980728185029468 -0.0811603768920226 AKS(ph)PQPPVEEEDEHFDDTVVCLDTYNCDLHFK ddPTM_PC-9_Lapatinib_30min_R1 3 AKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK 32 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1W2PRI6 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 1 AKS(1)PQPPVEEEDEHFDDTVVCLDTYNCDLHFK;AKS(0.981)PQPPVEEEDEHFDDT(0.019)VVCLDTYNCDLHFK;AKS(0.948)PQPPVEEEDEHFDDT(0.051)VVCLDT(0.001)YNCDLHFK 89.96799999999999 5.5299e-10 21106600.0 55174.7 78301.7 96381.2 88300.8 73847.0 85622.6 76831.9 70209.2 101727.4 74516.4 True False 54387.89866019919 78120.39722449204 88457.10977819104 94794.73539483377 69503.46464878815 81960.7209940293 80809.87984062599 73471.37574328601 90269.78897498803 87396.4604531382 0.6223123725858654 0.8938622550552837 1.0121360672909807 1.0846518829634124 0.7952663561936328 0.9378036658358316 0.9246356136351319 0.8406676353063658 1.0328769438367644 1.0 16.41528723147087 -4.775376726831419 3.7904574023957345 0.9457531455596793 0.5873794858410153 0.5867752063600147 0.08280256687054756 0.18622545219124267 4.750636871021755 0.021090082730527537 0.188959968181205 1.6773483784224124e-05 4.775376726831419 -0.358373659718664 AKS(ph)PTPDGSER ddPTM_PC-9_AZD4547_30min_R2 2 AKSPTPDGSER 11 1 Q96MU7;Q96MU7-2;J3QR07 Q96MU7 YTHDC1 YTH domain-containing protein 1 1 AKS(0.908)PT(0.091)PDGS(0.001)ER;AKS(0.962)PT(0.038)PDGSER 120.6 0.0041034 19887000.0 80820.0 60016.0 74042.0 96784.0 90038.0 72178.0 64251.0 75333.0 60955.0 76595.0 True False 106519.07883956864 79414.99832315338 73060.15470181665 74471.94409789403 77537.77786900991 67664.6982498868 69969.2145293203 63692.01583012518 64176.95685790112 73913.43236370337 1.4411328960536396 1.0744325595972684 0.9884557159017048 1.0075562954706583 1.049035004726507 0.9154587479706174 0.9466373335908028 0.8617109744913211 0.8682719068180693 1.0 16.17354895019328 -1.5283914074030402 0.8698261373313169 0.9375717455095818 199.99999995075626 0.8747996588427646 0.05559545645372288 260.4654870104183 0.6685305685687377 0.020553587546231766 102725.39700744537 0.02962160542369308 1.5283914074030402 199.06242820524668 AKS(ph)PTPDGSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AKSPTPDGSER 11 1 Q96MU7;Q96MU7-2;J3QR07 Q96MU7 YTHDC1 YTH domain-containing protein 1 1 AKS(0.88)PT(0.082)PDGS(0.038)ER;AKS(0.929)PT(0.07)PDGSER 106.54 0.011684 20419100.0 51868.0 46456.0 35875.0 46089.0 44691.0 33924.1 49102.0 40763.0 35293.0 34257.0 True False 60648.227960303506 51067.84466299181 36730.396056695135 43506.78275255404 35934.11936702784 32145.060476035087 44450.703092304975 39693.01444196861 35809.09335720378 40467.52292173722 1.4986889135170214 1.261946394933914 0.9076512078026234 1.0751036784903945 0.887974275977385 0.7943421824509129 1.098429058241867 0.9808609861970924 0.8848847364949252 1.0 15.304476921714725 -5.01184438427674 2.3780617683248737 0.952628617284952 1.5215836124419015 0.799729113141611 0.0888774306796828 0.15444786419349255 1.4783541514022993 0.0241489417309324 0.14856052820416088 9.730958395031835e-06 5.01184438427674 0.5689549951569496 AKS(ph)PTPDGSER ddPTM_PC-9_Lapatinib_30min_R1 1 AKSPTPDGSER 11 1 Q96MU7;Q96MU7-2;J3QR07 Q96MU7 YTHDC1 YTH domain-containing protein 1 1 AKS(0.77)PT(0.23)PDGSER 131.08 0.00085251 7785100.0 29839.0 23789.0 26241.0 21268.0 31580.0 25395.0 22728.0 24221.0 28175.0 21951.0 True False 29413.490388197566 23733.91803209181 24083.56627318927 22832.11966796819 29722.526488668835 24308.915048636358 23904.744631041907 25346.396083107724 25001.6348040969 25745.201102131065 1.1424843904506483 0.9218773602870489 0.9354584637987445 0.8868495366337712 1.1544880294684723 0.9442115038139742 0.9285126395483152 0.9845095395665668 0.9711182563661305 1.0 14.65201591897649 -10.285123376531823 4.148501308774318 1.0000001015310358 0.9813069512027065 0.00041264979510124977 0.08648895518262846 116771247.3384196 282103587.44141257 263.08174142315846 0.021146874439226113 5.1865267657180294e-11 10.285123376531823 -0.0186931503283293 AKS(ph)PTPESSTIASYVTLR ddPTM_PC-9_AZD4547_30min_R2 2 AKSPTPESSTIASYVTLR 18 1 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;H0YGJ6 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 AKS(0.92)PT(0.08)PESSTIASYVTLR;AKS(0.912)PT(0.074)PES(0.009)S(0.005)TIASYVTLR 109.91 0.00011221 478320000.0 40083.9 45140.5 76682.0 110014.0 90443.0 106796.0 72505.0 82387.0 78399.0 102170.0 True False 52829.74640308574 59731.28385441061 75665.14657687128 84651.9719993566 77886.55060981886 100118.02923737011 78957.8045392034 69655.9822149193 82543.01108526932 98593.05939812791 0.5358363633869432 0.6058365996455202 0.7674490175959385 0.8585997078914459 0.7899800562563513 1.0154673143175752 0.8008454654030408 0.7064998554679391 0.8372091462539264 1.0 16.589198469110656 -5.265114235792184 1.870875492798094 0.8487010307555721 0.5296304104510995 0.6284992066602417 0.08789454516768276 0.27704249247002577 1.7098999875346501 0.02568916959942706 0.10822160569491726 5.431074550033332e-06 5.265114235792184 -0.31907062030447264 AKS(ph)PTPESSTIASYVTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AKSPTPESSTIASYVTLR 18 1 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;H0YGJ6 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 AKS(0.863)PT(0.135)PES(0.002)STIASYVTLR;AKS(0.861)PT(0.085)PES(0.042)S(0.012)TIASYVTLR 73.127 0.0034701000000000003 175779000.0 39000.0 63661.0 48986.0 60975.0 62117.0 50820.0 72854.0 56667.0 50977.0 38955.0 True False 45601.929714888516 69980.84335910805 50154.012020439535 57558.7684336172 49945.619760615526 48154.909736503054 65952.74170271656 55179.55129364952 51722.442185990934 46017.233132389665 0.9909750458853895 1.52075295700148 1.0898962976793614 1.2508089799319968 1.0853677277146163 1.0464538273729622 1.4332183230785143 1.1991062377631494 1.1239798367969587 1.0 15.489886621125724 -8.559897230514625 2.8631790058562063 1.0009518362488445 1.2085735582508372 0.1326956711860504 0.15898515527784904 0.5432923143216235 11.232524542776002 0.1466335812481868 0.03924140675427895 2.7548805287027504e-09 8.559897230514625 0.2076217220019927 AKS(ph)PTPESSTIASYVTLR ddPTM_PC-9_Lapatinib_30min_R1 2 AKSPTPESSTIASYVTLR 18 1 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;H0YGJ6 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 AKS(0.844)PT(0.15)PES(0.004)S(0.001)TIASYVTLR;AKS(0.774)PT(0.22)PES(0.004)S(0.002)TIASYVTLR 55.718 0.018378 303910000.0 23812.0 26561.0 33563.0 26558.0 39977.0 29815.0 25423.0 24974.0 21679.6 25524.0 True False 23472.436513414017 26499.49963640296 30803.579696926623 28511.163914890865 37625.631457806005 28539.881952159605 26739.278544305642 26134.383212069366 19237.81515169118 29935.789391407816 0.7840927862804609 0.8852113197993322 1.0289883889204499 0.9524106260272579 1.2568778783767542 0.9533699472228093 0.8932210938115552 0.873014667171946 0.6426359732879743 1.0 14.869583693419822 -7.543881620151531 2.328828694160418 0.8162656798688511 0.9853301664773315 0.1655518699277807 0.1394303532486607 0.5093538553011235 5.513652295585256 0.08193259606507054 0.042866476805998595 2.858369570643493e-08 7.543881620151531 0.1690644866084804 AKS(ph)PTPESSTIASYVTLRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AKSPTPESSTIASYVTLRK 19 2 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;H0YGJ6 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 AKS(0.606)PT(0.387)PES(0.003)ST(0.002)IASYVT(0.001)LRK 40.179 0.044045 12507000.0 14575.0 7480.4 11212.0 19011.0 22072.0 27568.0 21821.0 27896.0 19492.0 20189.0 True False 17042.259630628196 8223.004675758659 11479.33660174679 17945.87530449359 17747.15004517775 26122.28554930963 19753.956909640907 27163.759558255173 19777.033624758922 23849.105883963948 0.7145869414788983 0.34479299625600546 0.48133194835893006 0.7524758115380893 0.7441432031676655 1.0953150896476231 0.8282892031991604 1.1389844001036529 0.8292568166279528 1.0 14.541647559367192 -6.202599934449343 1.5113855706469488 0.975129302941588 0.49819545796060255 0.6659780495346304 0.1373413441669125 0.21714693988047845 0.9906327580822255 0.04755646007656769 0.06857135587514374 6.2719135789665e-07 6.202599934449343 -0.4769338449809854 AKS(ph)PTPESSTIASYVTLRK ddPTM_PC-9_Lapatinib_30min_R1 1 AKSPTPESSTIASYVTLRK 19 2 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;H0YGJ6 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 AKS(0.907)PT(0.092)PESSTIASYVTLRK 82.12100000000001 0.005483 11377000.0 58302.0 15158.0 15438.0 17512.0 10558.0 15282.0 8394.0 9027.2 17181.0 9459.6 True False 57470.60278872261 15122.902582304736 14168.74723240334 18799.89089831948 9936.999197826646 14628.424484081941 8828.600247842567 9446.636667413819 15245.89485604928 11094.679255875317 5.180014803788796 1.363077042024106 1.2770758762494296 1.6944961151863656 0.8956544816349146 1.3185081016501932 0.795750831928492 0.8514564909491406 1.3741627409350874 1.0 13.437580339770557 -4.760460022506948 5.268365914162718 1.1589181692780819 5.405752839799849 0.9542774537438286 0.2633917360557177 0.03156188549071533 2.5424539678153253 0.06840309655271214 0.4934394529664129 1.7359610534738682e-05 4.760460022506948 4.246834670521767 up AKS(ph)TCSCPDLQPNGQDLGENSR ddPTM_PC-9_Lapatinib_30min_R1 1 AKSTCSCPDLQPNGQDLGENSR 22 1 F5H7V1;O43847;O43847-2 F5H7V1 NRD1 Nardilysin 1 AKS(0.425)T(0.425)CS(0.151)CPDLQPNGQDLGENSR 122.59 2.0751999999999997e-05 0.0 9002.0 6832.5 8349.0 8084.7 7585.4 10863.0 8272.3 8358.9 14499.0 8808.6 True False 8873.629829235379 6816.679766037548 7662.577448071993 8679.275807768583 7139.241685470193 10398.41481288982 8700.599217325238 8747.285009664716 12865.969938761335 10331.154773278287 0.8589194551791226 0.6598177953609803 0.7416961236406392 0.8401070352965461 0.691040047520725 1.0065104086704326 0.8421710262079792 0.8466899588311001 1.245356421533766 1.0 13.334713901184175 -7.5640977288605855 0.7877097304176932 1.0805107650298167 0.7556139880295489 0.4906399679524751 0.11755883884203402 0.5453571917333625 0.633920121548455 0.10083867904262465 0.05065018258779603 2.7283637527085745e-08 7.5640977288605855 -0.32489677700026776 AKS(ph)VDEIAK ddPTM_PC-9_AZD4547_30min_R2 1 AKSVDEIAK 9 1 A6ND36;A6ND36-2 A6ND36 FAM83G Protein FAM83G 1 AKS(1)VDEIAK 64.945 0.024755000000000003 41112000.0 81310.0 71374.0 85236.0 102600.0 108170.0 99849.0 95712.0 77114.0 82859.0 83037.0 True False 107164.88864693564 94444.24970535775 84105.71494778707 78947.15515419834 93152.46265011214 93605.42624557277 104230.18258128756 65197.80320343362 87238.75757999896 80129.89990449561 1.3373895234445843 1.178639307149054 1.0496171222980448 0.9852396577094573 1.1625181456751814 1.1681710117838437 1.3007651663800446 0.813651374594763 1.0887166673610746 1.0 16.29005305407992 -4.8825110040846855 2.6662621952534056 1.076858630518707 1.360503205472212 0.3100815030189167 0.12278309787244807 0.4884319383587139 5.454377161242281 0.033048506842293934 0.2826695919410986 1.3106568327304446e-05 4.8825110040846855 0.28364457495350504 AKS(ph)VDEIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AKSVDEIAK 9 1 A6ND36;A6ND36-2 A6ND36 FAM83G Protein FAM83G 1 AKS(1)VDEIAK;AKS(1)VDEIAK 107.39 0.009611399999999999 46797000.0 258780.0 237826.0 221113.0 288202.0 254887.0 253709.0 236817.0 273710.0 215470.0 196830.0 True False 302586.34286202135 261435.79354272186 226385.17249572222 272054.9763034909 204943.7220716393 240404.05341083152 214383.97935339442 266525.40251971694 218620.84112080885 232513.72089457762 1.3013698361449166 1.1243886706421837 0.9736422075425213 1.170059879721427 0.8814263574774641 1.0339349113931706 0.9220272185597026 1.1462781701410227 0.9402492045617048 1.0 17.826956328216568 -3.7384671517721615 0.9518358519329382 1.0052247254889597 2.9884571833920686 0.5179352786782757 0.08722571597811564 9.528297763204586 1.5139343866035124 0.0268459040354519 30.96456997209376 0.00018261348650956634 3.7384671517721615 1.9832324579031089 AKS(ph)VDEIAK ddPTM_PC-9_Lapatinib_30min_R1 1 AKSVDEIAK 9 1 A6ND36;A6ND36-2 A6ND36 FAM83G Protein FAM83G 1 AKS(1)VDEIAK 78.705 0.010009 41174000.0 144200.0 97907.0 107260.0 142110.0 107350.0 96259.0 86210.0 93638.0 118660.0 128810.0 True False 142143.6815569587 97680.30235688829 98441.4968355734 152561.24346506267 101035.8840582203 92142.22696068854 90673.53197123024 97988.76332232515 105295.26125480517 151074.63687146385 0.9408838207428312 0.6465698305136148 0.6516083630856491 1.0098402129198143 0.6687812471406624 0.6099119539111272 0.6001903022833435 0.6486116091458501 0.6969751073728654 1.0 17.20490194876387 -4.751055753822941 24.636599758812963 0.7120753005473881 0.9408843952306497 0.160630118256486 0.144429030336796 652.5068791510923 1548038.0967193418 0.03577739691124974 0.48520286936637413 1.7739617287516035e-05 4.751055753822941 0.2288090946832616 AKSES(ph)LELPQAAPPQIYHEK ddPTM_PC-9_AZD4547_30min_R2 1 AKSESLELPQAAPPQIYHEK 20 1 B0QY58;B0QY55;B0QY57;B0QY56;H0YGT9;Q15040 B0QY58 JOSD1 Josephin-1 1 AKS(0.431)ES(0.569)LELPQAAPPQIYHEK 55.17100000000001 0.009721700000000002 10983000.0 42205.0 39820.0 57764.0 87197.0 77260.0 64778.0 52934.0 76451.0 66413.0 61767.0 True False 55625.31208146494 52691.036277458836 56998.011617672855 67095.07883022053 66533.78260467495 60727.421419700884 57645.023453254245 64637.25461920926 69923.45559517329 59604.55613041162 0.9332392637864745 0.8840102116048584 0.9562693746592831 1.1256703041864793 1.1162533021654009 1.0188385815143475 0.9671244481232271 1.0844347951822066 1.173122662673378 1.0 15.863134993047662 -5.600485199193145 5.3260831309944345 1.0679879412275732 0.9110022837108036 0.560797181480944 0.05963080016374147 0.15078958466074507 7.43587835869707 0.01735621118001311 0.030798837822268502 2.509081687806384e-06 5.600485199193145 -0.15698565751676963 AKSPQPPVEEEDEHFDDT(ph)VVCLDTYNCDLHFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK 32 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1W2PRI6 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 1 AKS(0.045)PQPPVEEEDEHFDDT(0.95)VVCLDT(0.004)Y(0.001)NCDLHFK;AKS(0.081)PQPPVEEEDEHFDDT(0.912)VVCLDT(0.007)YNCDLHFK;AKS(0.332)PQPPVEEEDEHFDDT(0.66)VVCLDT(0.006)Y(0.002)NCDLHFK 64.383 5.1064e-05 11282700.0 20461.4 20238.2 22840.300000000003 25130.9 28377.5 26324.6 26634.0 28502.5 22579.300000000003 19810.1 True False 23925.1108889287 22247.31474639576 23384.899374320103 23722.897148477103 22817.13258458823 24944.09163419022 24111.034706538463 27754.33957589507 22909.479546661154 23401.514313334676 1.0223744740867333 0.9506784239906548 0.9992900058179096 1.0137334204461843 0.9750280378901185 1.0659178419054938 1.0303194222264278 1.1860061363669983 0.9789742338856614 1.0 14.514314269257744 -6.767927493648278 24.89707998052445 1.0624986678343247 0.9915008278074356 0.2167933915521435 0.055344077875189815 189.59062350817564 727518.9085206902 0.018369052983485144 0.016580167347838695 1.7063672467243897e-07 6.767927493648278 -0.07099784002688903 AKSPQPPVEEEDEHFDDT(ph)VVCLDTYNCDLHFK ddPTM_PC-9_Lapatinib_30min_R1 1 AKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK 32 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1W2PRI6 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 1 AKS(0.447)PQPPVEEEDEHFDDT(0.553)VVCLDTYNCDLHFK 62.376999999999995 0.00015704 2521700.0 7611.1 10268.0 12076.0 10716.0 8614.6 9899.5 11569.0 8616.8 12751.0 9185.5 True False 7502.564318295206 10244.225076864035 11083.15789470804 11504.090387528067 8107.906164955247 9476.121461861618 12167.986212448257 9017.167985174956 11314.848106017374 10773.2014360906 0.6964099170337013 0.950898870464403 1.028771063128837 1.067843245647386 0.7525995139934429 0.8796012511300755 1.1294679937650733 0.8369998499208535 1.050277224754402 1.0 13.395159413985187 -4.762758942401548 6.020815932486438 0.9626646629916569 0.6868760043285224 0.35493861891443557 0.10915528763525455 0.1525968365638888 21.54385883647934 0.027190153886103748 0.17390105092902183 1.7267960939364575e-05 4.762758942401548 -0.2757886586631345 AKSTCS(ph)CPDLQPNGQDLGENSR ddPTM_PC-9_AZD4547_30min_R2 1 AKSTCSCPDLQPNGQDLGENSR 22 1 F5H7V1;O43847;O43847-2 F5H7V1 NRD1 Nardilysin 1 AKS(0.151)T(0.202)CS(0.647)CPDLQPNGQDLGENSR 74.525 0.00044661 4931100.0 4944.0 6400.6 7008.9 12038.0 10872.0 9190.2 6449.8 7928.6 6455.3 10258.0 True False 6516.08915841163 8469.468779445077 6915.95740646609 9262.825085245999 9362.610464380332 8615.535341185818 7023.819705081781 6703.417051102841 6796.513979243856 9898.870542292192 0.6582659234275386 0.855599509384419 0.6986612641228284 0.9357456535744421 0.9458261348483417 0.8703553909889599 0.709557688937645 0.677190091785016 0.6865948948626263 1.0 13.273048208239082 -10.25209047910435 15.20738131788026 0.9999999578807135 0.7884213275240636 0.27524097509098855 0.10567147731054405 0.0 0.0 0.11069021762207655 0.02684632111637806 5.5964099607370536e-11 10.25209047910435 -0.21157863035664992 AKT(ph)PEPGAQQSGFPTLSR ddPTM_PC-9_AZD4547_30min_R2 1 AKTPEPGAQQSGFPTLSR 18 1 Q9H9D4 Q9H9D4 ZNF408 Zinc finger protein 408 1 AKT(0.997)PEPGAQQS(0.002)GFPTLSR 55.912 0.027697000000000003 6472500.0 18685.0 13879.0 13723.0 16359.0 19499.0 14757.0 10287.0 14262.0 13825.0 15747.0 True False 24626.441327856242 18365.1153313624 13541.024053551078 12587.685294030507 16791.900427239903 13834.242457169501 11202.523071440397 12058.135608156384 14555.761275703107 15195.702323013777 1.620618830533399 1.208572986030963 0.8911087994296453 0.8283714057076883 1.105042733155459 0.9104049397057249 0.7372165388153373 0.7935227574111154 0.9578867081160518 1.0 13.8913757351937 -4.873557261300587 2.007812794268818 0.8923425932828574 1.7548657469928612 0.8311085526199341 0.10085200537356191 0.23681239444061306 1.2345628694889645 0.029103438459868406 0.35615284450003626 1.3379587949717734e-05 4.873557261300587 0.8625231537100039 AKT(ph)PEPGAQQSGFPTLSR ddPTM_PC-9_Lapatinib_30min_R1 3 AKTPEPGAQQSGFPTLSR 18 1 Q9H9D4 Q9H9D4 ZNF408 Zinc finger protein 408 1 AKT(0.999)PEPGAQQS(0.001)GFPTLSR;AKT(1)PEPGAQQSGFPTLSR;AKT(1)PEPGAQQSGFPTLSR 90.59200000000001 0.0052527 4215400.0 128568.0 108442.8 91597.5 79972.5 125970.3 116094.1 110333.2 116543.2 102916.7 108065.9 True False 126734.59674351626 108191.70735930558 84066.70712657519 85853.94443043922 118560.97462113884 111129.0259715651 116045.71323150609 121958.22253386908 91325.13748510377 126744.94682623935 0.9999183392870307 0.8536175213961841 0.6632746253925706 0.677375679112008 0.935429597707589 0.876792556660402 0.9155845352209477 0.9622334111754954 0.7205426312601301 1.0 16.951568704237033 -6.29486505718716 24.980820218608155 0.8993179400259891 0.7928178342309049 0.16908766262730968 0.111726211520804 1180.5961964123273 882320.2471483462 0.03606951239057188 0.04090165022161751 5.071482635397021e-07 6.29486505718716 -0.10650010579508418 AKT(ph)QT(ph)PPVSPAPQPTEER ddPTM_PC-9_Lapatinib_30min_R1 1 AKTQTPPVSPAPQPTEER 18 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 AKT(0.703)QT(0.71)PPVS(0.574)PAPQPT(0.014)EER 61.126999999999995 0.039822 17796000.0 48333.0 68490.0 69439.0 54078.0 92433.0 86386.0 96639.0 104870.0 89085.0 84939.0 True False 47643.76255681334 68331.41561301303 63729.99346229152 58055.07651891965 86996.27267027 82691.4721556016 101642.4945617414 109742.6430467573 79051.30919336183 99620.59297589658 0.4782521478098494 0.6859165717829643 0.6397271041913104 0.5827618044089158 0.8732759971757942 0.8300640428391044 1.020296020385404 1.1016060010133624 0.7935237768810357 1.0 16.604156378000617 -6.4922550590337735 1.369644831274402 0.9796933551205489 0.5926842209302562 0.7468620126478009 0.09745961818868329 0.2075186730428092 0.8007238264130728 0.04002540579781639 0.04581816720937466 3.2191776286617943e-07 6.4922550590337735 -0.3870091341902927 AKT(ph)QTPPVS(ph)PAPQPTEER ddPTM_PC-9_AZD4547_30min_R2 1 AKTQTPPVSPAPQPTEER 18 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 AKT(0.981)QT(0.019)PPVS(1)PAPQPTEER 128.09 0.00015605 44754000.0 177320.0 199260.0 221850.0 218490.0 192400.0 211500.0 163600.0 244790.0 204680.0 195760.0 True False 233704.07151487615 263666.8982583234 218908.1240457849 168120.50613685005 165688.58106574498 198274.8715654505 178160.08306480478 206963.33021459836 215498.96693749804 188906.5019847062 1.2371414909466523 1.3957534308674548 1.1588173077468114 0.889966752708496 0.877093055691429 1.0495926264173943 0.9431124984741317 1.0955860599830176 1.1407705117261913 1.0 17.527312833228514 -5.524363435769666 5.071682607994889 0.9986350626388135 1.3108131022430307 0.6851518603454176 0.08654136965954845 0.09901703583941025 7.576127161853803 0.02494689477290458 0.04789781030431338 2.9897616319825235e-06 5.524363435769666 0.3121780396042172 AKT(ph)QTPPVS(ph)PAPQPTEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AKTQTPPVSPAPQPTEER 18 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 AKT(0.628)QT(0.372)PPVS(0.999)PAPQPT(0.001)EER 104.45 0.0013348 25491000.0 143380.0 131550.0 140750.0 169400.0 207490.0 197850.0 243660.0 190870.0 204580.0 205570.0 True False 167651.40211591558 144609.41461633728 144106.01379734732 159909.06720220967 166833.823979428 187474.39770498074 220578.76085436525 185859.8647434815 207571.5954726649 242838.2137087751 0.6903831137424373 0.5954969459203848 0.5934239574425759 0.6585004261066646 0.6870163531160886 0.7720135757949954 0.9083362848274589 0.7653649806795847 0.8547731936522813 1.0 17.889635940470903 -6.811960296430633 1.4315851993919204 0.8692075637914393 0.6251152303793817 0.769718756118297 0.06135757545068676 0.19831688350869206 0.8460683929644635 0.02832782946913473 0.02453741213459487 1.541841402953518e-07 6.811960296430633 -0.2440923334120576 AKT(ph)QTPPVS(ph)PAPQPTEER ddPTM_PC-9_Lapatinib_30min_R1 2 AKTQTPPVSPAPQPTEER 18 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 AKT(0.628)QT(0.372)PPVS(1)PAPQPTEER;AKT(0.731)QT(0.269)PPVS(0.997)PAPQPT(0.003)EER 107.83 0.0010457 84603000.0 199537.0 216510.0 228570.0 215787.0 313280.0 329770.0 343750.0 345660.0 318910.0 288990.0 True False 196691.5657893954 216008.68439733525 209777.8569057147 231656.69582432948 294853.486332178 315666.50583141623 361547.69301833207 361720.62549386895 282990.9975288215 338941.53644502955 0.5803111883317239 0.6373036679509126 0.6189204755072474 0.6834709556522595 0.8699243221256777 0.9313302498780992 1.0666963300231833 1.0672065433105564 0.8349256939617307 1.0 18.370676920793436 -6.359614923700201 1.5797254747590839 0.9958475923874271 0.609037391157462 0.8756614829016021 0.0629368914374876 0.12422579630941392 0.6195106538435239 0.023958868925547196 0.030016544766736396 4.369030497886794e-07 6.359614923700201 -0.3868102012299651 AKT(ph)QTPPVS(ph)PAPQPTEERLPSSPVYEDAASFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 AKT(0.559)QT(0.473)PPVS(0.847)PAPQPT(0.06)EERLPS(0.024)S(0.024)PVY(0.011)EDAAS(0.002)FK 42.468 0.044366 3588800.0 5002.5 3103.7 4089.1 7939.0 6471.4 8843.2 8494.9 10516.0 8526.2 7270.9 True False 5849.324446121273 3411.8148243612814 4186.599651998108 7494.203568585279 5203.375625333604 8379.447024436124 7690.201574249963 10239.966142623012 8650.879545014333 8589.056613587272 0.681020595075373 0.3972281215336309 0.48743416656204214 0.8725293016150325 0.6058145684011719 0.9755957378579201 0.8953488049065383 1.1922108100235502 1.0071978721538826 1.0 13.068283965078109 -6.599481499743845 0.8280856103230301 1.0736961092846948 0.5146582331638526 0.6987282058157365 0.13359669497899263 0.3265050576634748 0.4950575001173352 0.08007573493245702 0.0905787584864034 2.5148871409175413e-07 6.599481499743845 -0.5590378761208422 AKT(ph)QTPPVSPAPQPTEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AKTQTPPVSPAPQPTEER 18 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 AKT(0.596)QT(0.402)PPVS(0.002)PAPQPTEER;AKT(0.946)QT(0.054)PPVS(0.001)PAPQPTEER 101.75 0.0003652 22312000.0 80840.0 68058.0 76560.0 99660.0 103921.0 85138.0 83934.0 65722.0 71081.0 69446.0 True False 94524.61533722004 74814.34846034748 78385.48075541682 94076.3733020794 83558.42605314044 80673.21340311681 75983.16389046324 63996.86713821501 72120.42515295955 82036.01006576644 1.1522332115060416 0.9119696143238863 0.9555008915301576 1.14676924470925 1.0185578989781867 0.9833878236940448 0.9262172042442 0.78010701747818 0.8791313119097602 1.0 16.323969705615 -7.242838056145753 2.388970054471915 0.8712416456925003 1.0296230917208289 0.365543329276922 0.08631007812061889 0.31474992259533463 3.5300265877419346 0.04067211368115486 0.027209670468661518 5.716917747936521e-08 7.242838056145753 0.1583814460283286 AKT(ph)QTPPVSPAPQPTEER ddPTM_PC-9_Lapatinib_30min_R1 1 AKTQTPPVSPAPQPTEER 18 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 AKT(0.546)QT(0.453)PPVS(0.001)PAPQPTEER 76.76100000000001 0.003776 273940000.0 19667.0 19411.0 20955.0 21359.0 19191.0 20426.0 14203.0 17741.0 16385.0 11629.0 True False 19386.544973513912 19366.055022108274 19232.160788639198 22929.812111535273 18062.223110957686 19552.427595331617 14938.36184418727 18565.31162670467 14539.548758300887 13639.057155331513 1.421399203238598 1.4198969035435176 1.41007993218368 1.6811874787526644 1.324301445858899 1.433561526479018 1.095263526947525 1.3611873178086569 1.06602300970763 1.0 13.735456296320486 -7.733256081076403 0.6727107112830651 1.0148172822015542 1.475660190284175 0.6403910950607961 0.11855317580489648 0.45678172080681434 0.40982391853626576 0.10932059540446414 0.05657350584277087 1.8481785219864938e-08 7.733256081076403 0.46084290808262085 AKT(ph)QTPPVSPAPQPTEERLPS(ph)SPVYEDAASFK ddPTM_PC-9_AZD4547_30min_R2 1 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 AKT(0.499)QT(0.413)PPVS(0.088)PAPQPT(0.03)EERLPS(0.466)S(0.466)PVY(0.035)EDAAS(0.004)FK 54.31100000000001 0.0018701 19257000.0 43543.0 24464.0 55694.0 83547.0 76860.0 49509.0 36062.0 43654.0 35246.0 53767.0 True False 57388.76824933608 32371.509580405644 54955.46117018684 64286.52993828267 66189.31570017229 46413.19440346988 39271.44813864917 36908.27736912486 37109.031603864874 51884.633695401106 1.10608409777446 0.6239132335490489 1.0591856828519524 1.2390283087607272 1.275701705609981 0.894546055310858 0.7568994004891677 0.7113527597747364 0.715222002370118 1.0 15.663019708615854 -6.994737184646181 24.9602887409992 0.779515740504476 1.0502057286218254 0.3220447733843709 0.18147600659790566 179.9880922374757 853634.2474235187 0.06936739308260198 0.06098002274612763 1.0121918016009189e-07 6.994737184646181 0.27068998811734934 AKT(ph)QTPPVSPAPQPTEERLPS(ph)SPVYEDAASFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 AKT(0.536)QT(0.137)PPVS(0.317)PAPQPT(0.195)EERLPS(0.385)S(0.385)PVY(0.041)EDAAS(0.003)FK 50.088 0.010028 6152200.0 16821.0 7239.2 11598.0 18970.0 21142.0 27970.0 17743.0 24007.0 22882.0 19879.0 True False 19668.463070106143 7957.859933793925 11874.540305659932 17907.172401569802 16999.376869116888 26503.203961629068 16062.254591804147 23376.84168751908 23216.60596150899 23482.905337922577 0.8375651473731197 0.33887884907251087 0.5056674263590255 0.762562048600157 0.723904330596801 1.1286169057978106 0.6839977575460047 0.9954833676294639 0.9886598624581798 1.0 14.519323291290096 -6.216002917575807 1.6804067039503185 0.9382506141671765 0.5460337466035193 0.4945399040776801 0.16566970889732965 0.2996430551860324 1.6752448050064024 0.05712491302169962 0.07940319955680497 6.081309158618378e-07 6.216002917575807 -0.39221686756365715 AKT(ph)QTPPVSPAPQPTEERLPS(ph)SPVYEDAASFK ddPTM_PC-9_Lapatinib_30min_R1 2 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 AKT(0.524)QT(0.377)PPVS(0.099)PAPQPT(0.087)EERLPS(0.404)S(0.404)PVY(0.098)EDAAS(0.007)FK;AKT(0.517)QT(0.405)PPVS(0.077)PAPQPT(0.005)EERLPS(0.485)S(0.485)PVY(0.025)EDAAS(0.001)FK 76.237 7.5119e-07 34935000.0 185396.0 70125.0 90987.0 77812.0 73538.0 78542.0 49138.0 51141.0 87535.0 63178.0 True False 182752.2190425374 69962.62987096701 83506.40007997703 83534.5540532227 69212.63942127064 75182.94175034446 51682.12520591946 53517.197559399385 77675.88651558555 74098.2331206066 2.4663505639207246 0.9441875591971506 1.1269688434278473 1.127348798145524 0.9340659892472215 1.014638792101457 0.6974812087867011 0.7222466083947194 1.0482825736094914 1.0 16.177151521290682 -4.761256912350467 24.999728049600957 0.9521377548372921 2.466352235050319 0.9132010598442659 0.13956917118540899 1.261011436988298 172312.20396313438 0.03851137536806714 0.21674569577939173 1.7327786475521073e-05 4.761256912350467 1.5142144802130266 AKT(ph)QTPPVSPAPQPTEERLPSSPVYEDAASFK ddPTM_PC-9_AZD4547_30min_R2 1 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 AKT(0.527)QT(0.434)PPVS(0.038)PAPQPTEERLPSSPVYEDAASFK 45.558 0.0078523 31866000.0 52040.0 28366.0 57232.0 107900.0 93722.0 62089.0 43293.0 46340.0 40468.0 62382.0 True False 68587.63750075662 37534.75477263678 56473.0662852755 83025.32203838207 80710.31805947867 58206.56501478598 47145.99313034601 39179.21778726455 42607.055862940564 60198.025167603024 1.1393669029805427 0.6235213641665605 0.9381215767135797 1.379203417507857 1.340746940364994 0.9669181813311577 0.7831817239698875 0.6508389216786095 0.7077816214786818 1.0 15.877428538832797 -7.178162194043016 3.79337793528875 0.754435121394829 1.0726062951549178 0.2909803151837964 0.21602399379166076 0.3277673552922044 8.908270852883803 0.09721904619965382 0.0726316705369327 6.634952314899524e-08 7.178162194043016 0.31817117376008874 AKT(ph)QTPPVSPAPQPTEERLPSSPVYEDAASFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 AKT(0.509)QT(0.451)PPVS(0.032)PAPQPT(0.002)EERLPS(0.002)S(0.002)PVY(0.002)EDAASFK;AKT(0.525)QT(0.463)PPVS(0.011)PAPQPTEERLPSSPVYEDAASFK 51.843999999999994 0.002689 64508000.0 59549.5 16673.8 41258.6 77668.0 74521.0 80910.0 55109.1 75409.0 73489.0 54951.0 True False 69630.0541937629 18329.064670694712 42242.36149811185 73316.51376305356 59919.14500347455 76666.93716608547 49888.76709266724 73429.59365244009 74563.6375974711 64913.18130812333 1.0726643308891302 0.282362754394861 0.6507516754971548 1.1294549471399675 0.9230659135169544 1.1810688618413354 0.768546019272423 1.1311969645100572 1.1486671288461423 1.0 15.986223842010682 -5.7505183820906085 23.15636878772229 1.0354115340985268 0.629969388872001 0.3858526515133801 0.21316560274577517 79.72721147608249 169045.30559107676 0.05511031982316175 0.09406545753563908 1.7761580884479064e-06 5.7505183820906085 -0.4054421452265258 AKT(ph)TQDVNAGEGSEFADSGIEGATTDTDLLSR ddPTM_PC-9_AZD4547_30min_R2 2 AKTTQDVNAGEGSEFADSGIEGATTDTDLLSR 32 1 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 AKT(0.488)T(0.488)QDVNAGEGS(0.023)EFADSGIEGATTDTDLLSR;AKT(0.712)T(0.287)QDVNAGEGS(0.001)EFADSGIEGATTDTDLLSR 108.55 7.2409e-16 9701400.0 12444.3 13123.4 18496.300000000003 21535.9 24500.0 24242.0 20994.9 22327.2 23076.0 22494.8 True False 16401.328542480143 17365.28240792575 18251.026976732268 16571.130981338214 21098.597900783487 22726.143907752466 22863.40542748946 18877.044268014943 24295.750249412304 21707.26389888424 0.7555686713387759 0.7999756435825305 0.8407797068183418 0.76339105004339 0.9719602617383741 1.0469372839255249 1.0532605829085924 0.8696187762744815 1.1192451689252791 1.0 14.405890271864832 -6.346368758059979 4.471967971413008 1.0113042775119205 0.7942747374065524 0.7456933394495162 0.06326978264788642 0.11516286707359269 4.131438602916046 0.01941052767276019 0.022286162728026495 4.5043407998055013e-07 6.346368758059979 -0.21702954010536812 AKT(ph)TQDVNAGEGSEFADSGIEGATTDTDLLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AKTTQDVNAGEGSEFADSGIEGATTDTDLLSR 32 1 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 AKT(0.484)T(0.484)QDVNAGEGS(0.033)EFADSGIEGATTDTDLLSR 101.06 2.4028e-13 3145400.0 5361.0 4941.0 4394.7 5736.7 5440.2 5169.5 6970.6 4520.5 5347.6 4837.7 True False 6268.511415423521 5431.509826068594 4499.486314992559 5415.291297632339 4374.231862802465 4898.402319615355 6310.294305226292 4401.841664865664 5425.7985333347415 5714.736714787873 1.0969029245394035 0.9504392060641428 0.787347963616479 0.9476011875786565 0.7654301643474459 0.8571527550761681 1.1042143531997388 0.7702614983950414 0.9494398087132424 1.0 12.480471317831569 -4.8327836389368235 3.682644864798899 0.8912700271658722 1.1083833270585337 0.249171366877594 0.10324185105182927 0.31905495599833184 7.313706091763597 0.025140383936115313 0.1720450336982876 1.469658263990695e-05 4.8327836389368235 0.21711329989266148 AKT(ph)TQDVNAGEGSEFADSGIEGATTDTDLLSR ddPTM_PC-9_Lapatinib_30min_R1 1 AKTTQDVNAGEGSEFADSGIEGATTDTDLLSR 32 1 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 AKT(0.473)T(0.473)QDVNAGEGS(0.055)EFADSGIEGATTDTDLLSR 79.782 3.6215e-05 0.0 6251.0 5135.0 6435.9 3615.3 7717.1 6659.9 6865.9 4416.6 7338.4 4709.3 True False 6161.859593706993 5123.110222993457 5906.765145292436 3881.1812222872577 7263.195350402353 6375.071601985169 7221.382706893291 4621.811359590997 6511.872115222166 5523.296230252185 1.1156127313898665 0.9275458004466915 1.069427548162258 0.7026929319903686 1.315011009299193 1.154215044101318 1.307440775553618 0.8367849861603336 1.178982955785597 1.0 12.431313790027797 -6.277836004820904 24.97973199796293 1.1337872366967539 0.9602007069896684 0.2166796303720402 0.165839371776032 1321.0119613593195 2012514.5124373815 0.05073167222418186 0.057691642640408256 5.27428987789854e-07 6.277836004820904 -0.17358652970708544 AKTQT(ph)PPVS(ph)PAPQPTEER ddPTM_PC-9_AZD4547_30min_R2 3 AKTQTPPVSPAPQPTEER 18 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 AKT(0.053)QT(0.947)PPVS(1)PAPQPTEER;AKT(0.433)QT(0.621)PPVS(0.947)PAPQPTEER;AKT(0.189)QT(0.811)PPVS(0.999)PAPQPT(0.001)EER 152.63 0.00012335 74312000.0 274292.0 303365.0 295967.0 328797.0 333871.0 312412.0 284673.0 335802.0 319966.0 295865.0 True False 361511.15037197387 401421.8036240907 292042.28419859783 252997.93151301125 287518.7746829584 292876.8282529809 310008.3455153248 283911.51686230104 336878.7495364648 285506.8564042975 1.2662082967984805 1.4059970701917208 1.0228906159263849 0.8861360973928718 1.007046829992103 1.0258136422413862 1.0858175156267753 0.9944122548856151 1.179932257246464 1.0 18.123165866545783 -5.269527861462018 24.72850758089639 1.0216204862587885 1.3361026873753963 0.7244965990649685 0.07664833672022242 227.75423515235062 696303.2092624359 0.020188214561427945 0.04323392906403018 5.376159421322558e-06 5.269527861462018 0.31448220111660774 AKTQT(ph)PPVS(ph)PAPQPTEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AKTQTPPVSPAPQPTEER 18 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 AKT(0.151)QT(0.849)PPVS(1)PAPQPTEER;AKT(0.261)QT(0.742)PPVS(0.994)PAPQPT(0.003)EER;AKT(0.062)QT(0.938)PPVS(1)PAPQPTEER;AKT(0.204)QT(0.8)PPVS(0.996)PAPQPT(0.001)EER 108.14 0.0010189 33850900.0 192714.0 205514.0 216480.0 248873.0 310554.0 282230.0 331969.0 296278.0 289916.0 281135.0 True False 225336.67392500097 225916.0717252909 221641.70420497132 234929.45266715225 249703.17303054204 267429.36196248065 300522.49307257135 288501.0164324902 294155.47303281375 332102.55003656406 0.6785153378081309 0.6802599730126067 0.6673893475993149 0.7074003275231907 0.7518857443372537 0.805261392702456 0.9049087188264113 0.8687106329075962 0.8857368695314974 1.0 18.34126927499794 -7.080417682699323 0.49537293624118406 0.9773387930366498 0.6430268731445535 0.9458465727589508 0.025537362405774217 0.22337425357548654 0.11809908670906188 0.026235037969398915 0.027225784331113886 8.309642068835848e-08 7.080417682699323 -0.3343119198920963 AKTQT(ph)PPVS(ph)PAPQPTEER ddPTM_PC-9_Lapatinib_30min_R1 1 AKTQTPPVSPAPQPTEER 18 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 AKT(0.218)QT(0.798)PPVS(0.983)PAPQPTEER 72.654 0.028557 16986000.0 45686.0 59783.0 61650.0 59676.0 78419.0 85512.0 80773.0 78564.0 89095.0 72123.0 True False 45034.5092622137 59644.5761365566 56581.374975882005 64064.772113300234 73806.54859768595 81854.85109820802 84955.03071467561 82214.37025198262 79060.18288805713 84589.36445214345 0.532389734263721 0.7051072735071866 0.6688946694698599 0.7573620221433981 0.8725275225284629 0.9676730831157564 1.004322839696225 0.9719232528162038 0.9346350265202139 1.0 16.368188662082474 -6.102002530467826 1.0129586591154343 0.9851278151045084 0.6024296005862312 0.9315282153829005 0.040976745031391815 0.13264631700528834 0.2812073354937527 0.017748362026160192 0.03319977618642571 7.906740210313206e-07 6.102002530467826 -0.38269821451827724 AKTQT(ph)PPVS(ph)PAPQPTEERLPS(ph)SPVYEDAASFK ddPTM_PC-9_AZD4547_30min_R2 1 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 3 AKT(0.401)QT(0.775)PPVS(0.753)PAPQPT(0.176)EERLPS(0.428)S(0.428)PVY(0.037)EDAAS(0.002)FK 42.536 0.030107 5377900.0 11282.0 8693.5 13451.0 22800.0 19876.0 12714.0 12988.0 14262.0 12596.0 13197.0 True False 14869.44131982201 11503.50386434175 13272.630951272726 17543.812256488523 17116.560484733585 11918.991570133025 14143.906838910083 12058.135608156384 13261.79884475634 12734.977046854177 1.1676064483755857 0.903299929165037 1.0422186787177101 1.3776084709019742 1.3440589976533768 0.9359256421335507 1.1106346550034767 0.9468517739602061 1.0413680995233752 1.0 13.636508738893045 -6.7966648801536 24.998485189913207 1.0101141958621118 1.1570840850852735 0.25855719997413573 0.13490423708465518 317.1944283396087 225101.32890323322 0.053052848961147175 0.04679015393340558 1.5971110697945623e-07 6.7966648801536 0.14696988922316168 AKTQT(ph)PPVS(ph)PAPQPTEERLPS(ph)SPVYEDAASFK ddPTM_PC-9_Lapatinib_30min_R1 1 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 3 AKT(0.332)QT(0.658)PPVS(0.866)PAPQPT(0.156)EERLPS(0.448)S(0.45)PVY(0.083)EDAAS(0.006)FK 40.753 0.045867000000000005 3836300.0 20862.0 8732.4 12010.0 8817.9 12245.0 13438.0 9865.6 10384.0 14232.0 11017.0 True False 20564.50405437775 8712.180664317058 11022.584159940674 9466.397781652087 11524.773174596263 12863.288065507993 10376.392495248463 10866.47854865574 12629.042290395982 12921.27377077026 1.5915229736016858 0.6742509151091 0.8530570867459918 0.7326210983213135 0.8919223738349172 0.9955123847469715 0.8030471824473934 0.8409758001751533 0.977383694087858 1.0 13.657460676531187 -4.752610864847429 24.999971818855297 0.8569827327841723 1.5915243719500884 0.8162435408277133 0.10363356509086247 136.31262930755892 385972.0684822692 0.025399882423190176 0.29811601682731587 1.7676209293856112e-05 4.752610864847429 0.7345416391659162 AKTQT(ph)PPVS(ph)PAPQPTEERLPSSPVYEDAASFK ddPTM_PC-9_AZD4547_30min_R2 2 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 AKT(0.257)QT(0.746)PPVS(0.923)PAPQPT(0.02)EERLPS(0.025)S(0.025)PVY(0.004)EDAASFK;AKT(0.126)QT(0.863)PPVS(0.867)PAPQPT(0.103)EERLPS(0.015)S(0.015)PVY(0.009)EDAAS(0.001)FK 53.895 0.0024384 13228000.0 26522.0 18830.6 32342.0 65186.0 47336.0 35396.0 20866.7 33415.0 26043.0 36447.0 True False 34955.444308129685 24917.223197546875 31913.12394811259 50158.37481366058 40764.213478836224 33182.682524494914 22723.79587584578 28251.47955031172 27419.579812161737 35171.00162360343 0.9938711635858252 0.7084593001987411 0.9073703470160923 1.4261286997296958 1.1590290750059038 0.9434670891552277 0.6460946469205964 0.803260591002106 0.7796075899572995 1.0 15.102098801144143 -7.009294367653543 22.979593974992014 0.7914078541518867 1.0364515489482953 0.24853478263196882 0.1891649645164829 232.93966433442145 575926.4371093378 0.07619248095633799 0.06357715397723149 9.788263056091246e-08 7.009294367653543 0.24504369479640853 AKTQT(ph)PPVS(ph)PAPQPTEERLPSSPVYEDAASFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 AKT(0.241)QT(0.781)PPVS(0.944)PAPQPT(0.017)EERLPS(0.007)S(0.007)PVY(0.005)EDAASFK 49.888000000000005 0.010426999999999999 2767700.0 4665.1 1304.6 4310.8 7015.8 12091.0 9266.0 9787.1 14345.0 10567.0 8565.3 True False 5454.809290075035 1434.112066198965 4413.585820800037 6622.727471530493 9721.855345969738 8780.074648139258 8859.995035532118 13968.458949783868 10721.522384200058 10118.121087122501 0.5391128691884761 0.1417369938401096 0.43620606857702865 0.6545412349294126 0.96083603489811 0.8677574198349735 0.8756561578224616 1.3805388203509201 1.0596357062622541 1.0 13.304653789150802 -6.154902898289587 0.9619681446216156 1.097946599485453 0.2910318354979349 0.7750113992346107 0.15978577041172648 0.2618349293359312 0.5062567840011684 0.07439847071357691 0.13373759676193978 6.99998487634524e-07 6.154902898289587 -0.806914763987518 AKTQT(ph)PPVSPAPQPT(ph)EERLPSSPVYEDAASFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 AKT(0.188)QT(0.643)PPVS(0.15)PAPQPT(0.332)EERLPS(0.298)S(0.298)PVY(0.089)EDAAS(0.002)FK 40.544000000000004 0.027833 32140000.0 6200.4 4092.9 4473.6 8679.9 8787.9 10543.0 8388.4 10068.0 10143.0 6630.0 True False 7250.00525651781 4499.216062966229 4580.267590222477 8193.593343615486 7065.974079467987 9990.10652010924 7593.790025243194 9803.725667927778 10291.322186329247 7831.966516948874 0.9256941077095181 0.5744682453927298 0.5848170546069734 1.0461731834379053 0.9021966659557047 1.275555315320873 0.9695891841224995 1.251757862691559 1.3140150898319305 1.0 12.935158881838747 -6.135407412136309 1.4809918827200745 1.1586364463802956 0.6890769655165163 0.5675112692539004 0.16203700234016308 0.27700112740270233 1.2185057225176028 0.057581472557848866 0.08869838207900968 7.321373919839673e-07 6.135407412136309 -0.4695594808637793 AKTQT(ph)PPVSPAPQPTEER ddPTM_PC-9_AZD4547_30min_R2 3 AKTQTPPVSPAPQPTEER 18 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 AKT(0.048)QT(0.947)PPVS(0.005)PAPQPTEER;AKT(0.033)QT(0.79)PPVS(0.177)PAPQPTEER;AKT(0.129)QT(0.871)PPVSPAPQPTEER 90.06 0.00099288 502772000.0 101285.0 87594.0 114960.0 130944.0 131312.0 125641.0 96236.0 132621.0 116383.0 110738.0 True False 133491.5231411247 115907.04750596995 113435.55528647044 100756.88386463294 113081.59541010928 117784.64840829668 104800.81756616509 112127.47177740184 122534.76777939644 106861.09632602383 1.249206004155654 1.0846514914309668 1.061523409233876 0.9428771304875305 1.0582110730467078 1.1022219728023943 0.9807200297330563 1.049282438908457 1.146673316971722 1.0 16.705377197908007 -4.709654339667336 2.287880449200389 1.0416999664671969 1.3271495979432737 0.555394360236898 0.05533011694645335 0.6014130838360545 3.1624167276557453 0.01467585399037353 0.3745946654701378 1.9513971228692655e-05 4.709654339667336 0.2854496314760768 AKTQT(ph)PPVSPAPQPTEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 AKTQTPPVSPAPQPTEER 18 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 AKT(0.105)QT(0.878)PPVS(0.017)PAPQPTEER;AKT(0.151)QT(0.821)PPVS(0.028)PAPQPTEER;AKT(0.187)QT(0.778)PPVS(0.036)PAPQPTEER;AKT(0.042)QT(0.958)PPVSPAPQPTEER;AKT(0.027)QT(0.967)PPVS(0.006)PAPQPTEER 90.59200000000001 0.00095414 678710000.0 159807.0 148641.0 158072.0 178713.0 189898.0 154227.0 157833.0 137812.0 118839.0 139342.0 True False 186859.16876787622 163397.09614585317 161841.03597139852 168700.29000536376 152688.8500941988 146139.06461888325 142881.9156280353 134194.58102388395 120576.7955537003 164603.60156933512 1.1352070488516408 0.9926702367871717 0.9832168581270505 1.0248882065578802 0.9276154873797368 0.8878242227119547 0.8680363872102147 0.8152590814810201 0.7325282946674186 1.0 17.328636377081978 -6.391235700131835 0.8555460373643736 0.8330174404451133 1.05786896809513 0.5656390658168404 0.07222824227399773 0.4386405912075133 0.7015430173830414 0.0386581210351278 0.054932269473455836 4.062228042471407e-07 6.391235700131835 0.2248515276500168 AKTQT(ph)PPVSPAPQPTEER ddPTM_PC-9_Lapatinib_30min_R1 2 AKTQTPPVSPAPQPTEER 18 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 AKT(0.179)QT(0.82)PPVSPAPQPTEER;AKT(0.242)QT(0.757)PPVS(0.001)PAPQPTEER 83.792 0.0014847999999999999 402570000.0 56736.0 69442.0 72519.0 60345.0 62685.0 65089.0 61349.0 59821.0 56993.0 44265.0 True False 55926.9342358919 69281.21131550382 66556.76775143536 64782.97260501877 58997.99154345173 62305.295199869724 64525.351037037624 62600.50204729727 50573.84817710357 51916.14627059503 1.077255117211359 1.33448293627958 1.282005166649526 1.2478386255281706 1.1364093019529034 1.2001140237783605 1.2428763626005954 1.2058002479809211 0.9741448818929049 1.0 15.66389567577852 -8.24375159050322 6.478986286483754 0.9857995686961594 1.2212723308601379 0.6420088054260192 0.06825800731073933 0.08914889128762789 17.571765622293633 0.05145131624429637 0.01746997191974176 5.704904904111667e-09 8.24375159050322 0.2354727621639785 AKTQT(ph)PPVSPAPQPTEERLPS(ph)SPVYEDAASFK ddPTM_PC-9_AZD4547_30min_R2 3 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 AKT(0.259)QT(0.574)PPVS(0.151)PAPQPT(0.045)EERLPS(0.442)S(0.442)PVY(0.077)EDAAS(0.011)FK;AKT(0.269)QT(0.682)PPVS(0.048)PAPQPT(0.033)EERLPS(0.445)S(0.445)PVY(0.075)EDAAS(0.003)FK;AKT(0.158)QT(0.692)PPVS(0.151)PAPQPT(0.025)EERLPS(0.458)S(0.458)PVY(0.056)EDAAS(0.004)FK 64.542 9.227399999999999e-05 89134000.0 203877.0 102218.0 207034.0 387947.0 317111.0 217685.0 159526.0 193306.0 161505.0 246463.0 True False 268705.64509496116 135257.96951806333 204288.59388638774 298511.81287140126 273085.6113842998 204073.12253770712 173723.50495718888 163434.99942997337 170041.82458100785 237834.40538749858 1.129801403868228 0.5687064884396787 0.8589530751597719 1.2551245997610911 1.1482174369993576 0.8580471030051985 0.7304389147320584 0.6871798012726215 0.7149588988353569 1.0 17.859597906473773 -6.9959209580085835 24.590209710204874 0.762385594544488 0.9785729052520449 0.20341190648115604 0.19385972968207243 163.94508361293825 988320.1343036684 0.07351938024763517 0.0645540293327117 1.0094365877379652e-07 6.9959209580085835 0.21618731070755692 AKTQT(ph)PPVSPAPQPTEERLPS(ph)SPVYEDAASFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 AKT(0.406)QT(0.568)PPVS(0.025)PAPQPT(0.017)EERLPS(0.468)S(0.468)PVY(0.044)EDAAS(0.004)FK;AKT(0.241)QT(0.718)PPVS(0.041)PAPQPT(0.102)EERLPS(0.405)S(0.405)PVY(0.084)EDAAS(0.004)FK 60.527 0.00074268 50576000.0 71515.0 28727.0 46504.0 94845.0 99363.0 100463.0 76787.0 101404.0 93940.0 83802.0 True False 83621.07701436529 31578.826709870962 47612.83172740212 89531.1421416386 79893.5334332637 95194.54342499601 69513.17947026242 98742.25244641921 95313.6947829801 98994.63922373278 0.8447030836223113 0.3189953209335028 0.4809637380443881 0.9044039439276483 0.8070490893219012 0.9616131153309386 0.702191351121137 0.9974505005594984 0.9628167295763 1.0 16.595062781764547 -5.764715673519589 24.9838136598906 0.8947866341018894 0.5252981307252115 0.5440996523237434 0.1490412216626661 58.07234535018657 442843.62311557535 0.04026889920774501 0.06262735481030705 1.7190334458223462e-06 5.764715673519589 -0.36948850337667793 AKTQT(ph)PPVSPAPQPTEERLPS(ph)SPVYEDAASFK ddPTM_PC-9_Lapatinib_30min_R1 1 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 AKT(0.3)QT(0.673)PPVS(0.027)PAPQPT(0.019)EERLPS(0.482)S(0.482)PVY(0.017)EDAAS(0.001)FK 57.097 0.0013649 21919000.0 189280.0 72511.0 98130.0 84489.0 74311.0 83436.0 56391.0 55895.0 86083.0 67610.0 True False 186580.8324902996 72343.10523456271 90062.13019275406 90702.60290704167 69940.1730810472 79867.63677881558 59310.65005671793 58492.08575472958 76387.42604582332 79296.29841533801 2.352957656522967 0.9123137735338429 1.135767141626546 1.1438440976394604 0.8820105664291502 1.0072051076140403 0.7479624048282899 0.7376395484233053 0.9633164166846906 1.0 16.27496590143739 -4.760628947147112 24.999487353833835 0.9451438539898651 2.352959292225434 0.9126803070806231 0.1303887822570787 5.835605866810289 179902.15319552584 0.0360683044944948 0.21118631290558654 1.7352859595345786e-05 4.760628947147112 1.4078154382355688 AKTQT(ph)PPVSPAPQPTEERLPSSPVYEDAASFK ddPTM_PC-9_AZD4547_30min_R2 2 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 AKT(0.328)QT(0.66)PPVS(0.011)PAPQPTEERLPSSPVYEDAASFK;AKT(0.45)QT(0.537)PPVS(0.014)PAPQPTEERLPSSPVYEDAASFK 68.234 2.3343000000000003e-05 25281000.0 51427.0 25617.8 68103.0 117733.0 102740.0 70988.0 53293.0 61655.0 45316.0 78615.0 True False 67779.71625194888 33898.252866616895 67199.90972229025 90591.47580671773 88476.32442148965 66549.10913800549 58035.973757779066 52127.63644095368 47711.311245552395 75862.71277854366 0.8934523136525523 0.44683681383200385 0.8858094742598828 1.1941502286000485 1.1662689242311608 0.8772308120891196 0.7650131616990297 0.6871311943869347 0.6289164926757884 1.0 16.2111033415082 -10.748006831795673 4.847772526054905 1.0000275285984992 0.8428490854540531 0.047654777867242704 0.21598625796136559 7.164992022091105e-05 1.1452886768397634e-05 0.23310063477033913 0.05652530885774589 1.7864594722106508e-11 10.748006831795673 -0.15717844314444607 AKTQT(ph)PPVSPAPQPTEERLPSSPVYEDAASFK ddPTM_PC-9_Lapatinib_30min_R1 2 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 AKT(0.391)QT(0.601)PPVS(0.008)PAPQPTEERLPSSPVYEDAASFK;AKT(0.385)QT(0.588)PPVS(0.025)PAPQPTEERLPSSPVYEDAASFK 59.971000000000004 0.00034748 43819000.0 176877.0 53986.1 72905.0 59020.4 37439.5 41799.9 25114.1 22399.2 46377.4 24497.9 True False 174354.7015447307 53861.09850234608 66911.03232143822 63360.95710228274 35237.38221888906 40012.215717326086 26414.38521376495 23439.948604299847 41153.88883632734 28732.329373600107 6.068241084028906 1.8745816881743962 2.3287715886661644 2.2052147696907642 1.2264018611476013 1.392585167636641 0.9193262707768853 0.8158039781430664 1.4323199592073603 1.0 14.810387338640355 -2.8873063563868944 0.9940658897124296 1.2752164131512962 199.99999999985997 0.8902178469945683 0.4860802910951419 23.486002350868894 0.6968634571807985 0.16088639955183345 9957.685862608521 0.0012962645482805324 2.8873063563868944 198.72478358670867 AKTQTPPVS(ph)PAPQPT(ph)EERLPSSPVYEDAASFK ddPTM_PC-9_Lapatinib_30min_R1 1 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 AKT(0.206)QT(0.143)PPVS(0.648)PAPQPT(0.4)EERLPS(0.293)S(0.293)PVY(0.016)EDAASFK 61.498999999999995 0.00056633 18532000.0 88635.0 35893.0 44625.0 37813.0 35762.0 40290.0 26903.0 26350.0 39555.0 30060.0 True False 87371.0486463318 35809.891963759335 40956.1047574815 40593.89416047021 33658.54947079719 38566.89062057725 28295.905702610034 27574.317195404336 35099.89936738428 35255.83094756775 2.4782013725976126 1.0157154434117743 1.1616831501827645 1.1514093717104894 0.9546945445947358 1.093915235693457 0.8025879674965405 0.7821207571709964 0.9955771406887168 1.0 15.10557426354172 -4.7612125016981395 7.394276843766576 0.9927524656706539 2.5039018063461196 0.9313184138305405 0.12082459271984251 0.026841822889559455 9.993360951032546 0.03383009574452016 0.2028375876334304 1.7329558493542025e-05 4.7612125016981395 1.5111493406754657 AKTQTPPVSPAPQPT(ph)EERLPSSPVYEDAASFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 AKTQTPPVS(0.002)PAPQPT(0.711)EERLPS(0.136)S(0.136)PVY(0.014)EDAAS(0.001)FK 72.514 6.3438999999999995e-06 17885000.0 25744.0 5638.9 11446.0 34757.0 29050.0 68574.0 33363.0 45773.0 46705.0 39895.0 True False 30101.95073282281 6198.692725808173 11718.91604919673 32809.67797371437 23357.86103716989 64977.8587223723 30202.61511279726 44571.50725050237 47387.97226782091 47127.64769135375 0.6387322985005562 0.13152985624074365 0.2486632926375983 0.6961874734039354 0.4956296819680908 1.3787630383744665 0.6408682926548521 0.9457613404006087 1.0055238185909907 1.0 15.524286052655057 -6.295433336155382 1.6928758774781796 0.9587803822062301 0.3410524933239693 0.5440664817670032 0.24129929384775298 0.27291566508821774 1.548465007096095 0.0846014103352951 0.11022001726053955 5.06485088600435e-07 6.295433336155382 -0.6177278888822608 AKTQTPPVSPAPQPTEERLPS(ph)SPVYEDAASFK ddPTM_PC-9_AZD4547_30min_R2 4 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 AKTQTPPVSPAPQPT(0.107)EERLPS(0.433)S(0.433)PVY(0.025)EDAAS(0.003)FK;AKTQTPPVSPAPQPT(0.159)EERLPS(0.407)S(0.407)PVY(0.026)EDAAS(0.001)FK;AKTQTPPVSPAPQPT(0.016)EERLPS(0.471)S(0.471)PVY(0.042)EDAAS(0.001)FK;AKTQTPPVSPAPQPT(0.089)EERLPS(0.435)S(0.435)PVY(0.037)EDAAS(0.003)FK 81.406 6.966e-08 110998500.0 258267.0 95096.7 276267.0 757999.0 542342.0 275604.0 174505.0 229621.0 171933.0 312960.0 True False 340390.53371268214 125834.84855767508 272603.5190703487 583254.0415178087 467047.17480435583 258370.43831169914 190035.60693902103 194138.35061565574 181021.02737182385 302003.3656576104 1.127108411429402 0.41666704039430325 0.9026505995281088 1.9312832499325852 1.5464965888289475 0.8555217182732356 0.6292499639042753 0.6428350564667408 0.5994006953454035 1.0 18.204205102101362 -6.9874914493149305 23.67257255145466 0.695861632425766 1.1712620155332636 0.2518052802165741 0.38353647323238355 192.94205426689027 365141.72532276524 0.15284278907892 0.1346842747919998 1.0292207909937222e-07 6.9874914493149305 0.47540038310749755 AKTQTPPVSPAPQPTEERLPS(ph)SPVYEDAASFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 AKTQTPPVSPAPQPT(0.156)EERLPS(0.402)S(0.402)PVY(0.037)EDAAS(0.002)FK;AKTQTPPVSPAPQPT(0.16)EERLPS(0.374)S(0.374)PVY(0.089)EDAAS(0.001)FK;AKTQTPPVSPAPQPT(0.243)EERLPS(0.366)S(0.366)PVY(0.024)EDAAS(0.001)FK 72.514 4.296e-06 67288000.0 131135.0 21252.1 71269.0 174102.0 148882.0 325797.0 141668.0 238798.0 264303.0 192399.0 True False 153333.56546568955 23361.868037764092 72968.32324918751 164347.6293863 119709.64085837924 308711.63178716006 128248.1814525003 232529.80552739563 268167.9313628495 227279.41567035436 0.6746478338719608 0.10278919438814513 0.32105117409761663 0.7231082889823577 0.5267069193455067 1.3582912067800932 0.5642753923589421 1.0231010355317722 1.1799041746560972 1.0 17.794107501949107 -6.278230649504741 1.4383770571574968 0.9930612935389173 0.3516595020458824 0.5157990451630473 0.25900834887727586 0.3241160738080218 1.3467134654699775 0.09610531225789389 0.13134893224612826 5.269499291982244e-07 6.278230649504741 -0.6414017914930348 AKTQTPPVSPAPQPTEERLPS(ph)SPVYEDAASFK ddPTM_PC-9_Lapatinib_30min_R1 2 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 AKTQTPPVSPAPQPT(0.026)EERLPS(0.474)S(0.474)PVY(0.024)EDAAS(0.001)FK;AKTQTPPVSPAPQPT(0.014)EERLPS(0.486)S(0.486)PVY(0.013)EDAAS(0.001)FK 99.34 1.7386e-13 67580000.0 1939600.0 281266.0 384496.0 249552.0 208030.0 235122.0 113941.0 108617.0 322879.0 136946.0 True False 1911940.9483209255 280614.7458579322 352884.2230774813 267904.8865610677 195794.08440271614 225066.38015615175 119840.30746240514 113663.74234585332 286512.96695339854 160616.93363092508 11.90373209785149 1.7471056103134497 2.197054912580757 1.6679741077405645 1.219012715387925 1.4012618412534406 0.7461249866578897 0.7076697318044712 1.7838278970744434 1.0 17.29326447674098 -4.7605603687790214 5.7856474289757935 1.3580307854152387 12.349312702375386 0.9810168346668507 0.4392580290595008 0.01888732363465958 2.2352105617704034 0.12248494048407955 0.8270926092281732 1.735559995886572e-05 4.7605603687790214 10.991281916960148 up AKTQTPPVSPAPQPTEERLPSS(ph)PVYEDAASFK ddPTM_PC-9_Lapatinib_30min_R1 1 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 AKTQTPPVSPAPQPT(0.105)EERLPS(0.239)S(0.569)PVY(0.078)EDAAS(0.008)FK 69.08800000000001 1.3512e-05 19428000.0 326070.0 50432.0 75447.0 50271.0 44926.0 46410.0 22984.0 23639.0 70831.0 36528.0 True False 321420.18200608494 50315.22780253282 69244.03889384218 53968.09703913991 42283.5410079144 44425.15248699407 24173.999058424302 24737.35423841226 62853.266896503505 42841.816129499486 7.502487313668419 1.1744419902845198 1.616272258032567 1.2597060982664372 0.986968920274118 1.0369577319670245 0.5642617713813227 0.5774114282092472 1.467100897555666 1.0 15.386732018962695 -4.761209977191816 7.133244925196052 1.0572726783989912 7.631174404111774 0.9737209234088497 0.3167749064229176 0.016548189446347634 5.140537238644276 0.08668256431486582 0.5256682765604794 1.7329659228662936e-05 4.761209977191816 6.5739017257127825 AKTS(ph)PVKSNTPAAHLEIKPDELAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AKTSPVKSNTPAAHLEIKPDELAK 24 3 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3 B8ZZZ7 SPATS2L SPATS2-like protein 1 AKT(0.176)S(0.72)PVKS(0.052)NT(0.052)PAAHLEIKPDELAK 59.574 0.0065362 12538000.0 35053.0 11992.0 30282.0 62186.0 48616.0 87129.0 64155.0 99109.0 77390.0 57577.0 True False 40986.780571691976 13182.486507632984 31004.037725124508 58701.92002973222 39090.04379287609 82559.80185816169 58077.77395802262 96507.49376466565 78521.68234250418 68015.25432071881 0.6026115903121247 0.19381661715873838 0.4558394735823263 0.8630699188880403 0.5747246582149216 1.2138424340642702 0.8538933587480678 1.4189095479904354 1.1544716420855152 1.0 16.053570726865207 -6.3835082859037815 0.8631054681899463 1.1824465541184654 0.37020708902535765 0.6638081384192437 0.2083722889259658 0.34147109320976043 0.5548320077034729 0.10859327517455358 0.15520811032527065 4.1351542481216196e-07 6.3835082859037815 -0.8122394650931077 AKVPAQANGTPT(ph)TK ddPTM_PC-9_Lapatinib_30min_R1 1 AKVPAQANGTPTTK 14 1 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 AKVPAQANGT(0.091)PT(0.672)T(0.237)K 73.597 0.014499000000000001 10839000.0 43307.0 37217.0 38614.0 27450.0 33232.0 36189.0 36029.0 32283.0 41028.0 24985.0 True False 42689.434238468864 37130.82632310564 35439.30597435045 29468.764570515646 31277.359096625787 34641.28083067932 37894.40532874909 33782.9860348857 36406.99459600664 29303.623959580185 1.4567970943577604 1.2671069753803104 1.2093830450197385 1.0056355013005642 1.0673546432266556 1.1821500602949864 1.2931644693850344 1.1528603452420798 1.2424058760180807 1.0 14.838791472361244 -4.847424953152661 1.8275187281107819 1.1475336383122772 1.527930038698276 0.5349400796140582 0.09083315558641362 0.6234234062217879 2.424859546398444 0.02637221856622733 0.39547749443075003 1.4209377321760319e-05 4.847424953152661 0.38039640038599876 ALAAAGYDVEK ddPTM_PC-9_AZD4547_30min_R2 2 ALAAAGYDVEK 11 0 P10412;P22492;Q02539;P16402;P16403 P10412;P16402;P16403 HIST1H1E;HIST1H1T;HIST1H1A;HIST1H1D;HIST1H1C Histone H1.4;Histone H1t;Histone H1.1;Histone H1.3;Histone H1.2 0 ; 132.01 0.00059845 8464200.0 47450.0 54047.0 57199.0 61155.0 56689.0 57481.0 52007.0 57848.0 47056.0 53682.0 False True 62538.11297868765 71516.63580331026 56440.503886837294 47056.65958533139 48818.710873368 53886.70398323239 56635.52224909117 48908.92081479669 49543.28409327204 51802.60951952912 1.2072386615023967 1.3805604865590628 1.089530130051841 0.9083839602248504 0.942398680803209 1.040231457122205 1.093294773649194 0.9441400977369386 0.9563858761708649 1.0 15.660737154026126 -5.450982895886047 4.6013960014260515 0.986731348675857 1.2896536993565535 0.7859542878615782 0.06398032543778209 0.09363706740512998 3.7145145811252513 0.017599257328338815 0.03744563534443351 3.5401128307520576e-06 5.450982895886047 0.3029223506806965 ALAAAGYDVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALAAAGYDVEK 11 0 P10412;P22492;Q02539;P16402;P16403 P10412;P16402;P16403 HIST1H1E;HIST1H1T;HIST1H1A;HIST1H1D;HIST1H1C Histone H1.4;Histone H1t;Histone H1.1;Histone H1.3;Histone H1.2 0 ; 135.55 0.00033474 7303900.0 36561.0 39716.0 39037.0 45921.0 66991.0 44220.0 51098.0 53849.0 37972.0 31836.0 False True 42750.05518733435 43658.74200610006 39967.79012864694 43348.1952478907 53864.594448917305 41901.02535513899 46257.627522516406 52435.52080773167 38527.26866403372 37607.61478636267 1.1367393393647618 1.1609016486185575 1.0627579110159393 1.152644098652321 1.432278934862143 1.114163330835148 1.23000694899934 1.3942793528811064 1.02445392729359 1.0 15.19873718778865 -6.014230915275848 24.884932580599642 1.2231327286894111 1.1214583391476938 0.04990881876502662 0.13395946839738002 1404.5815340069855 2456129.501506828 0.03716903380056851 0.049968648240141904 9.677631577641418e-07 6.014230915275848 -0.10167438954171737 ALAAAGYDVEK ddPTM_PC-9_Lapatinib_30min_R1 4 ALAAAGYDVEK 11 0 P10412;P22492;Q02539;P16402;P16403 P10412;P16402;P16403 HIST1H1E;HIST1H1T;HIST1H1A;HIST1H1D;HIST1H1C Histone H1.4;Histone H1t;Histone H1.1;Histone H1.3;Histone H1.2 0 ;;; 167.12 1.1282e-07 23285600.0 162882.0 188588.0 218073.0 195724.0 179029.0 188987.0 247481.0 225191.0 196374.0 175503.0 False True 160559.27281109965 188151.33607281194 200143.87972612344 210118.19587612344 168498.86620455643 180904.4665602143 260294.35524616696 235654.19596016314 174256.29221010537 205838.45970695262 0.780025623198328 0.9140727944655171 0.9723347134012933 1.0207917226706018 0.8185975859149175 0.8788662080826087 1.2645564663510498 1.1448501718078268 0.8465681897260111 1.0 17.651153040947555 -7.198023885892352 24.999871022279 1.076066339291795 0.9036300014075689 0.3189774048797739 0.11848771505836987 259.4179141723937 102268.43977445371 0.04630053519690922 0.035864232710675396 6.338348498254158e-08 7.198023885892352 -0.1724363378842262 ALAAEMT(ph)DY(ph)FS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 ALAAEMTDYFSR 12 0 Q8N3C0-4;Q8N3C0 Q8N3C0-4 ASCC3 Activating signal cointegrator 1 complex subunit 3 3 ALAAEMT(1)DY(1)FS(1)R 53.967 0.039618 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALAAFLK ddPTM_PC-9_Lapatinib_30min_R1 2 ALAAFLK 7 0 M0R2L9;M0QYF7;M0R140;P39019 M0R2L9 RPS19 40S ribosomal protein S19 0 ; 140.79 0.011720999999999999 5961000.0 57261.0 59325.0 78158.0 66371.0 58339.0 62473.0 68665.0 59291.0 54289.0 58703.0 False True 56444.44763961867 59187.636607417146 71732.15093860458 71252.14474716558 54907.614718886995 59801.175421675944 72220.13771957469 62045.8763124371 48174.40113148589 68849.73533316921 0.8198208368772895 0.8596639670581677 1.0418653113405176 1.0348935170537827 0.7974992852650019 0.8685752404463636 1.0489530187748122 0.9011781383354968 0.6997035050079164 1.0 16.071163488023586 -6.263655320410314 24.999410463046964 0.8883217029365614 0.940732865544955 0.05180553074233074 0.11087880728941073 777.4909112618134 8771364.754014144 0.03565320294722508 0.042358560509027636 5.449349711300758e-07 6.263655320410314 0.052411162608393624 ALAAGADS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 ALAAGADSPK 10 0 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 ALAAGADS(1)PK;ALAAGADS(1)PK;ALAAGADS(1)PK;ALAAGADS(1)PK 117.09 0.00098586 28720800.0 248474.0 299155.0 217693.0 213909.0 210581.0 251619.0 250395.0 248490.0 253917.0 230047.0 True False 327483.5634197353 395851.0034551276 214806.24858192052 164595.58491110546 181345.46304264886 235885.22415331978 272679.6699206102 210091.58023213968 267338.53423817037 221993.1245508576 1.4751968741478312 1.7831678537613445 0.9676256821760684 0.741444516554824 0.8168967548411773 1.0625789633375764 1.2283248432684704 0.946387779608952 1.2042649283803577 1.0 17.76015546934559 -5.268735064277628 24.98969505696678 0.9892215252716773 1.6291823745658336 0.7197112585934012 0.15802691109158032 263.9282729634824 904028.1346011919 0.04403617992144844 0.09469016814365934 5.38598247201419e-06 5.268735064277628 0.6399608492941563 ALAAGADS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 ALAAGADSPK 10 0 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 ALAAGADS(1)PK;ALAAGADS(1)PK;ALAAGADS(1)PK;ALAAGADS(1)PK 118.9 0.0008342 51989600.0 383942.0 514220.0 279677.0 339215.0 399680.0 327723.0 408706.0 396824.0 301572.0 292709.0 True False 378466.91667365946 513029.3551835829 256683.03664444052 364162.0026880674 376171.6082011137 313707.05124962627 429866.7968661829 415261.8917172348 267605.785666055 343303.360639774 1.1024270661619953 1.494390716792025 0.7476857673810434 1.0607586305284677 1.0957411180015455 0.91378963102781 1.2521485256220353 1.2096062530333527 0.7795023770444589 1.0 18.389124454524307 -5.250716585554607 24.994449747027097 1.0253478899021298 1.2984088560099236 0.294093552794534 0.1786170945128516 925.4567247489839 2157197.2037988435 0.04440849465677551 0.11496252124970321 5.614142275102783e-06 5.250716585554607 0.27306096610779385 ALAAGADS(ph)PKTEEARPSPAPGPGTPTGTPTR ddPTM_PC-9_AZD4547_30min_R2 1 ALAAGADSPKTEEARPSPAPGPGTPTGTPTR 31 2 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 ALAAGADS(0.873)PKT(0.08)EEARPS(0.022)PAPGPGT(0.018)PT(0.005)GT(0.001)PTR 55.417 0.0049232 19441000.0 12158.0 8924.1 11322.0 11932.0 15558.0 9787.5 10712.0 10718.0 10352.0 11949.0 True False 16023.991097890077 11808.640804712959 11171.862882336623 9181.26174756233 13398.040250628159 9175.486077762864 11665.347248106315 9061.779375138141 10899.185585973139 11530.669146992534 1.38968440544229 1.0241071575445322 0.9688824421131279 0.796247089437738 1.1619481991747789 0.7957461931128293 1.0116799900679578 0.7858849525226091 0.9452344393053632 1.0 13.493188617347107 -4.653551007547457 2.002587306775601 0.9262663010862867 1.6458265757740107 0.6003862217590671 0.11137192515825886 0.7339961505636479 2.4031853541439845 0.027880814616172745 1.0946581054446036 2.2204908732175405e-05 4.653551007547457 0.719560274687724 ALAAGADS(ph)PKTEEARPSPAPGPGTPTGTPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ALAAGADSPKTEEARPSPAPGPGTPTGTPTR 31 2 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 ALAAGADS(0.609)PKT(0.166)EEARPS(0.217)PAPGPGT(0.004)PT(0.001)GT(0.001)PT(0.001)R;ALAAGADS(0.819)PKT(0.17)EEARPS(0.011)PAPGPGTPTGTPTR;ALAAGADS(0.899)PKT(0.073)EEARPS(0.022)PAPGPGT(0.002)PT(0.001)GT(0.001)PT(0.001)R 59.661 0.00030689 80267000.0 51535.6 38237.8 27897.8 49106.2 51000.0 43755.1 50474.0 44853.7 45957.6 39244.2 True False 60259.5592055028 42033.79607918349 28562.989354995665 46354.93881844847 41006.91610656328 41460.50552954868 45692.73731988519 43676.33790142354 46629.64295676279 46358.862803083706 1.299849814294721 0.906704641520833 0.6161279122898525 0.9999153563224382 0.8845539693401533 0.894338278004326 0.9856311082084135 0.9421356621051168 1.005840957635852 1.0 15.500557556582487 -7.2729411165304345 22.497678429677713 0.9785799202653085 0.9187169001114287 0.01797724500257447 0.15744878272902224 940.6311704673564 1839877.31615879 0.06716186480813786 0.04583441092266794 5.3340721217474447e-08 7.2729411165304345 -0.05986302015387979 ALAAGADS(ph)PKTEEARPSPAPGPGTPTGTPTR ddPTM_PC-9_Lapatinib_30min_R1 3 ALAAGADSPKTEEARPSPAPGPGTPTGTPTR 31 2 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 ALAAGADS(0.756)PKT(0.228)EEARPS(0.015)PAPGPGTPTGTPTR;ALAAGADS(0.736)PKT(0.248)EEARPS(0.014)PAPGPGT(0.001)PTGTPTR;ALAAGADS(0.778)PKT(0.222)EEARPSPAPGPGTPTGTPTR 65.125 0.0003401 196406000.0 142508.0 91940.0 87924.6 112587.0 87547.0 78178.0 71234.0 65400.0 100983.0 65805.3 True False 140475.80978723377 91727.11857877686 80695.7787867712 120867.02355922217 82397.65758402449 74834.50918181895 74922.1479693612 68438.72275443797 89609.23114186748 77179.65842494961 1.8201144272209246 1.1884882681616604 1.045557604601745 1.5660476610784002 1.0676084769686942 0.9696144127741754 0.9707499294288322 0.8867456030657168 1.1610472625893329 1.0 16.235933038487936 -1.5228787452803376 0.6098217806869161 1.0285319918084712 47.88306437475408 0.5906548451859104 0.18037673028105394 137.8889434834401 1.0319256271728974 0.08442376117517628 8633.282105497297 0.029999999999999995 1.5228787452803376 46.85453238294561 ALAAGADSPKT(ph)EEARPSPAPGPGTPTGTPTR ddPTM_PC-9_AZD4547_30min_R2 1 ALAAGADSPKTEEARPSPAPGPGTPTGTPTR 31 2 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 ALAAGADS(0.27)PKT(0.73)EEARPSPAPGPGTPTGTPTR 76.60600000000001 1.0964e-05 22344000.0 44202.0 42228.0 46451.0 50943.0 42318.0 39250.0 45215.0 40456.0 41010.0 37435.0 True False 58257.31654128458 55877.37518645232 45835.02938945579 39198.87841150415 36442.87616185129 36795.69129524311 49239.04740693866 34204.454786395625 43177.70487642566 36124.412044327204 1.6126855288273962 1.546803727016701 1.2688103915217492 1.085107720601912 1.0088157591916875 1.0185824270327832 1.3630407976334362 0.9468515292214125 1.1952500382135927 1.0 15.140686486259339 -5.372437748810564 2.1822238702677126 1.090811710717918 1.6113411312573835 0.7498875565866093 0.11277052013066574 0.15708691930288707 1.4130522625839905 0.031388189132256696 0.09556888460842101 4.241917826350321e-06 5.372437748810564 0.5205294205394655 ALAEEASEEELPS(ph)DVDLNDPYFAEEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALAEEASEEELPSDVDLNDPYFAEEVK 27 0 Q9H501 Q9H501 ESF1 ESF1 homolog 1 ALAEEAS(0.005)EEELPS(0.991)DVDLNDPY(0.004)FAEEVK 90.37799999999999 4.6843999999999994e-05 0.0 815.78 815.98 553.78 763.18 1050.2 753.65 942.43 692.33 1081.2 704.92 True False 953.8754416105572 896.9851017760471 566.9842154223451 720.4214988629436 844.4208489237802 714.127267275 853.1562077976661 674.1570710842702 1097.0105045705589 832.7164158563498 1.1454985436183696 1.077179559206365 0.6808851184220611 0.8651462672584349 1.014055725147911 0.8575875936594873 1.0245459216992814 0.8095878239544249 1.3173878690050969 1.0 9.701681454760173 -8.255754170252501 24.995265479876696 1.1586939363914348 0.9314286628993689 0.267508097816616 0.14845806727822636 562.7396362465304 2474137.5740764476 0.10623516927313766 0.037705676131539974 5.549397443355618e-09 8.255754170252501 -0.22726527349206593 ALAENSGVK ddPTM_PC-9_Lapatinib_30min_R1 2 ALAENSGVK 9 0 P50990-2;P50990;P50990-3;H7C2U0 P50990-2 CCT8 T-complex protein 1 subunit theta 0 ; 102.61 0.014386000000000001 6543600.0 50580.0 46977.0 48353.0 40318.0 44078.0 48252.0 51369.0 40035.0 45761.0 42831.0 False True 49858.719924763995 46868.2276427583 44377.6029879776 43283.12021690527 41485.41870068225 46188.37444090577 54028.63546955264 41895.17225495304 40606.91429530712 50234.28128127988 0.9925238035274561 0.9329928974264838 0.8834127184878267 0.8616251514488175 0.8258388025577674 0.919459247008639 1.075533163638329 0.8339956536924823 0.8083506573515872 1.0 15.616384615340797 -4.873124553664678 2.874659008464362 0.8981118128567732 0.9998020890308787 0.11199328723418978 0.07830799828760224 0.7878694489399914 10.476073033912044 0.021093940933772513 0.1710374350727687 1.3392925293890135e-05 4.873124553664678 0.10169027617410553 ALAGCDFLTISPK ddPTM_PC-9_Lapatinib_30min_R1 2 ALAGCDFLTISPK 13 0 P37837;F2Z393 P37837 TALDO1 Transaldolase 0 ; 220.94 2.4553e-14 12470200.0 85566.0 77660.0 80898.0 82720.0 79587.0 69525.0 81162.0 66173.0 73439.0 73294.0 False True 84345.81314911721 77480.18304141621 74246.87871531045 88803.50474583064 74905.8491340622 66551.57782069076 85364.17123128398 69247.63915641337 65167.52647304596 85962.77024188399 0.9811900304257651 0.9013225472306292 0.863709702542076 1.0330461023528363 0.8713754678134549 0.7741907064351977 0.9930365318740234 0.8055538340791344 0.7580901161011459 1.0 16.39142435544951 -6.495156872748426 24.677883211337907 0.8575983299353317 0.9379536950928905 0.15548531249644548 0.08715219219630471 1143.6330263084164 1018058.1387212331 0.026569684602807314 0.03004964885346742 3.197739836327858e-07 6.495156872748426 0.08035536515755881 ALAMPGRPES(ph)PPVFR ddPTM_PC-9_Lapatinib_30min_R1 1 ALAMPGRPESPPVFR 15 1 Q63ZY3-3;Q63ZY3;Q63ZY3-2;K7ERU2 Q63ZY3-3 KANK2 KN motif and ankyrin repeat domain-containing protein 2 1 ALAMPGRPES(1)PPVFR 61.126999999999995 0.022749000000000002 5046100.0 17139.0 16870.0 18299.0 17441.0 17427.0 15514.0 15742.0 15183.0 18337.0 15456.0 True False 16894.594717092332 16830.938551489715 16794.526856182703 18723.669321470414 16401.97812280025 14850.502384900354 16557.043733802446 15888.457608266575 16271.69396282962 18127.54900617456 0.9319845011224485 0.9284729306624301 0.9264642920265831 1.03288477196188 0.9048094762956344 0.8192228513541469 0.9133636173408125 0.8764812939054635 0.8976223954648915 1.0 14.145896253573767 -6.501326950493395 24.964452656903156 0.8907748701358943 0.9532531884133348 0.19270369095216155 0.05092790896143981 1051.1769656965232 1217629.2784176597 0.015384419060144833 0.01727294410352579 3.152630330873825e-07 6.501326950493395 0.06247831827744055 ALANS(ph)LACQGK ddPTM_PC-9_AZD4547_30min_R2 2 ALANSLACQGK 11 0 P04075;J3KPS3;P04075-2;H3BR68 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 ALANS(1)LACQGK;ALANS(1)LACQGK 120.84 0.00082697 18614500.0 58881.0 72188.0 80162.0 135496.0 103436.0 107789.0 71350.0 106286.0 79790.0 89642.0 True False 77603.93319911705 95521.35928672012 79098.99950307964 104259.49059233208 89075.69683532423 101048.93679039409 77700.01177673499 89861.9409093052 84007.53650548661 86503.66086490113 0.8971173291765835 1.1042464368751117 0.9144006012255843 1.2052610207464107 1.0297332615140997 1.1681463625939408 0.8982280171712568 1.0388224037090052 0.9711442922246621 1.0 16.40047356894481 -9.928672611547857 7.706023646649136 0.9999999933358011 1.030592272927832 0.0029233745067779315 0.10358288066202062 0.0 0.0 0.09495665413535763 0.023030371633667498 1.1784940344222338e-10 9.928672611547857 0.030592279592030924 ALANS(ph)LACQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALANSLACQGK 11 0 P04075;J3KPS3;P04075-2;H3BR68 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 ALANS(1)LACQGK;ALANS(1)LACQGK 99.669 0.0044663 9101600.0 50037.0 58177.0 49957.0 61282.0 78159.0 72113.0 67547.0 67441.0 61650.0 49346.0 True False 58507.27582420194 63952.42808160141 51148.164342977514 57848.56821892468 62844.30501907612 68331.26733231885 61148.459162069325 65670.74520964595 62551.51461965872 58292.03917727894 1.003692384928728 1.0971039782483503 0.8774468188945094 0.992392255192762 1.0780941258196979 1.1722229706960225 1.0490018881669825 1.1265817105818985 1.0730713061765738 1.0 15.831011250562367 -6.291404897299933 5.309016398385202 1.0929470896058375 0.9916127754758214 0.309838454041535 0.06540871581195325 0.21822708163445204 17.880900230668278 0.020193716471293338 0.023665074912074632 5.112050115075773e-07 6.291404897299933 -0.10133431413001615 ALANS(ph)LACQGK ddPTM_PC-9_Lapatinib_30min_R1 2 ALANSLACQGK 11 0 P04075;J3KPS3;P04075-2;H3BR68 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 ALANS(1)LACQGK;ALANS(1)LACQGK 120.14 0.0008962 18733300.0 84557.0 86233.0 80583.0 51714.0 93115.0 86575.0 82974.0 80782.0 88549.0 71576.0 True False 83351.20167414549 86033.33278663953 73957.7767993753 55517.22007284684 87638.15877113363 82872.38906618208 87269.98772509994 84535.42662918978 78575.67915769218 83947.8162309749 0.9928930306514718 1.024843011400398 0.8809970302966201 0.6613301282322362 1.0439599587677788 0.98718933722071 1.0395742455644632 1.006999710350989 0.9360062320322691 1.0 16.357205175781196 ALANSLACQGK ddPTM_PC-9_Lapatinib_30min_R1 2 ALANSLACQGK 11 0 P04075;J3KPS3;P04075-2;H3BR68 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ; 192.12 0.0013219000000000002 65370000.0 217212.0 179127.0 208109.0 171106.0 200281.0 216146.0 203303.0 171178.0 191236.0 192848.0 False True 214114.51704819818 178712.24243703036 190999.08134397093 183689.70603288343 188500.86534759618 206901.93944093527 213829.03457078134 179131.55479601206 169696.98787564397 226181.5198461921 0.9466490330147233 0.7901275159816692 0.8444504284605306 0.8121340158904055 0.8334052467053032 0.9147605851337133 0.9453868499786778 0.7919813913967201 0.7502690228230904 1.0 17.787121533227847 ALAPEYAK ddPTM_PC-9_Lapatinib_30min_R1 1 ALAPEYAK 8 0 P07237;H7BZ94;I3NI03;I3L0S0;I3L3U6;I3L514 P07237 P4HB Protein disulfide-isomerase 0 100.15 0.022951 7042000.0 109720.0 91358.0 105160.0 101450.0 95381.0 102800.0 107850.0 97857.0 98085.0 92209.0 False True 108155.37267981602 91146.46616401874 96514.15072933894 108910.97142727915 89770.87710626109 98403.48363850435 113433.94528589725 102403.79346454205 87037.6344191603 108147.2027892309 1.0000755441691918 0.8428000337803924 0.8924331673879378 1.0070623059898902 0.8300804347313208 0.9099031791907167 1.0488846901289692 0.9468926687278058 0.8048070793729983 1.0 16.722636825133897 ALAPS(ph)PPAEFIYYCVDEDELKR ddPTM_PC-9_AZD4547_30min_R2 1 ALAPSPPAEFIYYCVDEDELKR 22 1 K7EN65;K7EPZ6;A0A0A0MS90;Q9UIS9-4;Q9UIS9-11;Q9UIS9-7 K7EN65 MBD1 Methyl-CpG-binding domain protein 1 1 ALAPS(0.999)PPAEFIY(0.001)YCVDEDELKR 57.413999999999994 0.0049799 4374400.0 6812.6 4506.2 8209.3 10338.0 8416.4 8549.5 8981.7 9500.5 8630.0 7170.6 True False 8978.865089117122 5962.741026456172 8100.439318138665 7954.73382050782 7247.928137638947 8014.89841346958 9781.053900141567 8032.4160247714035 9086.164181505812 6919.559476560772 1.297606461730984 0.8617226351842607 1.1706582399613719 1.1496011917310032 1.0474551396213136 1.158296050582287 1.4135370803985117 1.1608276584629855 1.3131130980641426 1.0 12.756464478418433 -7.006027365075898 24.59196542725253 1.2425067337050184 1.0984431935643422 0.12046785164582308 0.14347549997067163 368.13300575019446 1502007.2350342637 0.048440716632353754 0.041322929910062624 9.862173417085727e-08 7.006027365075898 -0.14406354014067624 ALAPS(ph)PPAEFIYYCVDEDELKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ALAPSPPAEFIYYCVDEDELKR 22 1 K7EN65;K7EPZ6;A0A0A0MS90;Q9UIS9-4;Q9UIS9-11;Q9UIS9-7 K7EN65 MBD1 Methyl-CpG-binding domain protein 1 1 ALAPS(0.973)PPAEFIY(0.023)Y(0.004)CVDEDELKR;ALAPS(0.937)PPAEFIY(0.027)Y(0.035)CVDEDELKR;ALAPS(1)PPAEFIYYCVDEDELKR 90.44200000000001 0.00071723 5335500.0 27428.3 20321.5 23084.9 26737.9 37320.2 29239.5 29849.7 29183.0 28581.9 22619.5 True False 32071.369456381442 22338.884219885225 23635.33156597077 25239.862148441378 30007.574715297327 27706.12914680205 27022.120322886574 28416.97717194439 28999.856215857642 26720.236294136517 1.200265188651014 0.8360286927846992 0.8845479997180004 0.9445972659298678 1.1230280445492236 1.0368968613081417 1.011297955056494 1.0635002198008332 1.0853143623666743 1.0 14.705645145552717 -6.235503405341949 23.936656143176524 1.0535903703738163 0.9512066950071162 0.1597812661418604 0.09520957592409396 719.2155931701085 663772.9049341704 0.027650529854775004 0.03568197245775773 5.814288732546773e-07 6.235503405341949 -0.10238367536670012 ALAS(ph)EKSPTADAKPAPK ddPTM_PC-9_AZD4547_30min_R2 1 ALASEKSPTADAKPAPK 17 2 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 ALAS(0.466)EKS(0.466)PT(0.068)ADAKPAPK 58.693000000000005 0.013219 107910000.0 118350.0 120260.0 143150.0 176820.0 159720.0 133120.0 144330.0 144530.0 114670.0 162330.0 True False 155982.83816707414 159131.69318752378 141251.73746745163 136056.88084176753 137545.63496788297 124795.98535599402 157175.09039574166 122196.20946899724 120731.2220965551 156646.8761094069 0.9957609244510629 1.0158625383399373 0.9017207427028239 0.868557894169184 0.8780617806372145 0.7966707568993124 1.00337200651206 0.7800743462234876 0.7707221816043925 1.0 17.25715647385274 -5.381872106777671 3.0336150748725226 0.8650524768394852 1.0079102621108391 0.3209101290004356 0.07664865276383875 0.28587469603719806 4.946838453784626 0.02051440720563832 0.05078734452008875 4.150762583813781e-06 5.381872106777671 0.14285778527135395 ALAS(ph)PEQLAQLPSSGVPR ddPTM_PC-9_AZD4547_30min_R2 3 ALASPEQLAQLPSSGVPR 18 0 Q9Y3Q8;Q9Y3Q8-2;H7BZ77 Q9Y3Q8 TSC22D4 TSC22 domain family protein 4 1 ALAS(0.676)PEQLAQLPS(0.162)S(0.162)GVPR;ALAS(1)PEQLAQLPSSGVPR;ALAS(1)PEQLAQLPSSGVPR 177.41 9.218299999999998e-33 6697500.0 38957.8 37392.9 41667.899999999994 60114.0 47067.1 48266.4 37258.3 55216.0 41208.6 47446.0 True False 51345.57002742081 49479.42366698617 41115.356420677774 46255.64605204169 40532.645602284356 45248.294377903796 40574.216521108974 46683.63593745357 43386.80246697569 45784.92998143843 1.1214513170214895 1.0806923519823122 0.8980106868645701 1.01028102632884 0.8852835554999562 0.988279208819317 0.8861915162381614 1.0196288594605143 0.9476219027650592 1.0 15.482585195803363 -5.13052362468872 5.04750965706451 0.9537175410775331 1.1117378961974482 0.5974403735779024 0.04853014775033017 0.1300951401868468 4.682572866365936 0.011437519519533184 0.03266595291607117 7.404169892585711e-06 5.13052362468872 0.15802035511991508 ALAS(ph)PEQLAQLPSSGVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALASPEQLAQLPSSGVPR 18 0 Q9Y3Q8;Q9Y3Q8-2;H7BZ77 Q9Y3Q8 TSC22D4 TSC22 domain family protein 4 1 ALAS(1)PEQLAQLPSSGVPR;ALAS(1)PEQLAQLPSSGVPR 97.271 0.00078303 2225200.0 13629.900000000001 16012.2 13159.0 16287.6 16771.0 13286.3 15997.3 15340.7 14692.2 13968.6 True False 15937.172867204084 17601.785395056777 13472.760465785408 15375.05857711167 13484.842941630845 12589.543038805583 14481.919933577663 14938.022879815213 14907.045630088392 16500.996604623248 0.9658309282203481 1.0667104428180483 0.8164816216016074 0.9317654530517198 0.8172138486382491 0.7629565256245339 0.877639107538518 0.9052800408206786 0.9034027451355112 1.0 14.010265540573739 -5.260888405668117 24.99996946046203 0.8692526063872285 1.0162706899903642 0.40288197168730355 0.06739235219078656 43.169562144852954 1958662.5975767383 0.01723946310384135 0.04030341862080862 5.484178657742342e-06 5.260888405668117 0.14701808360313573 ALAS(ph)PEQLAQLPSSGVPR ddPTM_PC-9_Lapatinib_30min_R1 1 ALASPEQLAQLPSSGVPR 18 0 Q9Y3Q8;Q9Y3Q8-2;H7BZ77 Q9Y3Q8 TSC22D4 TSC22 domain family protein 4 1 ALAS(1)PEQLAQLPSSGVPR 83.25200000000001 0.0023041999999999997 3135200.0 7463.9 16666.0 26618.0 28038.0 22560.0 23580.0 17555.0 20438.0 25919.0 24284.0 True False 7357.463417288373 16627.41090095598 24429.570788451354 30100.008052026118 21233.06515466652 22571.538367664733 18463.912002725297 21387.624092587237 22999.729280830077 28481.457043603954 0.25832468493533867 0.5837977627162855 0.8577359912117795 1.0568282376124307 0.7455048778635012 0.7924994263147641 0.648278350874318 0.7509315292347457 0.8075334504698417 1.0 14.797735332588747 -4.907031469398635 2.6023560248771602 0.8192116321351666 0.21665556731701058 0.7065327850301617 0.1153129818065071 0.21683179144614753 2.355701711993793 0.03211107054477846 0.2569081149396407 1.2387068253824559e-05 4.907031469398635 -0.602556064818156 down ALASEKS(ph)PTADAKPAPK ddPTM_PC-9_AZD4547_30min_R2 1 ALASEKSPTADAKPAPK 17 2 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 ALAS(0.15)EKS(0.676)PT(0.174)ADAKPAPK 44.925 0.037567 97727000.0 119010.0 104000.0 112190.0 156170.0 138320.0 133300.0 134270.0 133430.0 95750.0 130710.0 True False 156852.70443822147 137615.96616915416 110702.28729635624 120167.41930244784 119116.65557699493 124964.72992753913 146219.76988454402 112811.45941637257 100811.14952250088 126133.88268502738 1.2435413950580032 1.091030920793892 0.8776570176056039 0.9526973779323152 0.9443668349958324 0.9907308588889809 1.1592425981976127 0.894378711056389 0.7992392478255773 1.0 16.94459634578545 -4.956354690623859 3.336390323869112 0.9573269400652015 1.2407368008442972 0.5127924415691689 0.08954649310560549 0.22060601786049666 4.733689613053064 0.024356868026927745 0.12887712476221724 1.1057203673832614e-05 4.956354690623859 0.2834098607790957 ALASEKS(ph)PTADAKPAPK ddPTM_PC-9_Lapatinib_30min_R1 2 ALASEKSPTADAKPAPK 17 2 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 ALAS(0.135)EKS(0.55)PT(0.314)ADAKPAPK;ALAS(0.065)EKS(0.924)PT(0.011)ADAKPAPK 47.638999999999996 0.031837 165444000.0 255078.0 197092.0 190071.0 185316.0 196826.0 180829.0 182738.0 154136.0 173472.0 110536.0 True False 251440.54094442393 196635.64558329643 174444.09607527775 198944.7568360539 185249.0816548045 173095.3652029873 192199.27949609884 161297.7212611329 153933.7566188571 129642.00032003805 1.9394990845845517 1.5167588057718633 1.3455831878915778 1.5345702499570588 1.4289279801105597 1.3351796854081162 1.4825386759046455 1.2441779736732588 1.1873756671360494 1.0 16.984173660537934 -1.5228787452807488 0.12118093772829784 0.8837190319949128 3.587222745756012 0.7402895800629854 0.1213577377986229 52.77741515842026 0.4405265306390048 0.8509576979408835 24.108813117745285 0.02999999999997159 1.5228787452807488 2.7035037137610995 ALASIDSK ddPTM_PC-9_Lapatinib_30min_R1 1 ALASIDSK 8 0 P18206;P18206-2 P18206 VCL Vinculin 0 104.44 0.017776 2857700.0 32123.0 26892.0 32764.0 33921.0 36292.0 29738.0 32262.0 28371.0 27997.0 30278.0 False True 31664.92012936328 26829.73322623956 30070.27039269742 36415.66349713881 34157.37591281728 28466.175062663842 33932.36850082163 29689.220233427575 24843.683038519972 35511.511957101015 0.8916804265505638 0.7555221320525776 0.8467752775219265 1.0254608010250321 0.9618676882606528 0.8016041416950044 0.9555315060032634 0.8360449498543755 0.6995951923571121 1.0 15.115999166170656 -10.446882609448966 14.815321698059904 0.9999973364460435 0.8677956726785128 0.1572706138843203 0.09418276298102038 0.0 0.0 0.09513104045150668 0.023072666356262855 3.573694226720817e-11 10.446882609448966 -0.13220166376753073 ALASNTSFFS(ph)GCSPIEEEAH ddPTM_PC-9_AZD4547_30min_R2 1 ALASNTSFFSGCSPIEEEAH 20 0 O95239;Q2VIQ3 O95239 KIF4A;KIF4B Chromosome-associated kinesin KIF4A;Chromosome-associated kinesin KIF4B 1 ALASNTSFFS(0.882)GCS(0.117)PIEEEAH 149.23 0.00012384 23291000.0 20223.0 17341.0 21368.0 35730.0 29083.0 26877.0 18734.0 29055.0 22475.0 27004.0 True False 26653.493335468942 22946.139128262526 21084.646358396836 27493.00052299715 25045.327459121887 25196.376941203827 20401.289707433123 24565.217367478876 23662.982616378133 26058.598179377885 1.0228291311756685 0.8805592292536104 0.8091243517113937 1.055045261212647 0.9611156857601851 0.9669122171408131 0.7829005062742856 0.9426914371364445 0.9080681337304022 1.0 14.66947185585549 ALASNTSFFSGCS(ph)PIEEEAH ddPTM_PC-9_AZD4547_30min_R2 3 ALASNTSFFSGCSPIEEEAH 20 0 O95239;Q2VIQ3 O95239 KIF4A;KIF4B Chromosome-associated kinesin KIF4A;Chromosome-associated kinesin KIF4B 1 ALASNTSFFS(0.002)GCS(0.998)PIEEEAH;ALASNTSFFS(0.001)GCS(0.999)PIEEEAH;ALASNTSFFS(0.008)GCS(0.992)PIEEEAH 197.29 1.4972999999999999e-15 32585200.0 59700.2 58729.9 78883.0 128608.0 115335.0 94814.0 76222.0 98627.0 70335.0 89474.0 True False 78683.62175869875 77713.19164920953 77836.95987876342 98959.41257379268 99322.72607701487 88885.26559152073 83005.61033842055 83386.46337299398 74052.76450825162 86341.5424937662 0.9113066489908916 0.9000672145140373 0.9015006870462523 1.146139039396215 1.1503469037999396 1.0294611727366139 0.9613635330225134 0.9657745387049858 0.8576724757216166 1.0 16.397767246361198 -5.635504450546477 20.503699807645482 1.0187462914375383 0.9037623830089608 0.28264876633129876 0.08132402365368474 3.547106758862151 626.0525030559174 0.024767192345868227 0.04289805140017985 2.3147044653533026e-06 5.635504450546477 -0.11498390842857742 ALASNTSFFSGCS(ph)PIEEEAH ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ALASNTSFFSGCSPIEEEAH 20 0 O95239;Q2VIQ3 O95239 KIF4A;KIF4B Chromosome-associated kinesin KIF4A;Chromosome-associated kinesin KIF4B 1 ALASNTSFFSGCS(1)PIEEEAH;ALASNTSFFS(0.077)GCS(0.923)PIEEEAH;ALASNTSFFS(0.004)GCS(0.996)PIEEEAH;ALASNTSFFS(0.178)GCS(0.822)PIEEEAH 191.93 2.3515e-12 32692200.0 61904.0 57150.8 66090.2 72943.0 75000.0 75332.0 72910.0 83412.0 65337.0 56747.0 True False 72383.12454026824 62824.35372752093 67666.04101647934 68856.24019439658 60304.28839200478 71381.45730559317 66003.43697731155 81222.52338231933 66292.43001954001 67034.78189099507 1.0797845909004384 0.9371903951247175 1.0094168893770812 1.0271718390366866 0.8995969956322867 1.0648420908069218 0.9846147793042634 1.2116474625724132 0.9889258702644518 1.0 16.03262223095875 ALASNTSFFSGCS(ph)PIEEEAH ddPTM_PC-9_Lapatinib_30min_R1 4 ALASNTSFFSGCSPIEEEAH 20 0 O95239;Q2VIQ3 O95239 KIF4A;KIF4B Chromosome-associated kinesin KIF4A;Chromosome-associated kinesin KIF4B 1 ALASNTSFFS(0.011)GCS(0.989)PIEEEAH;ALASNTSFFS(0.001)GCS(0.999)PIEEEAH;ALASNTSFFS(0.001)GCS(0.999)PIEEEAH;ALAS(0.012)NT(0.227)S(0.183)FFS(0.123)GCS(0.454)PIEEEAH 201.75 3.2644000000000003e-16 34992000.0 56684.3 65266.4 89867.9 67986.1 69920.5 69966.8 59933.8 54273.299999999996 83350.9 71480.1 True False 55875.97148737251 65115.27966075567 82479.3081621261 72986.02458898124 65807.91365899214 66974.48306457694 63036.87890566434 56795.03565242269 73963.04391811178 83835.34004375387 0.6664966284887818 0.776704425923147 0.9838250565821042 0.8705878040321617 0.7849662639245792 0.7988812716644651 0.7519129626332433 0.6774593581034111 0.8822418311837262 1.0 16.355270906985304 -6.296048496614031 24.312607724516983 0.7957319343524227 0.8323837064261506 0.0 0.1096615112780218 2310.1263132034405 1622836.8410103759 0.03462454328072623 0.03926253423180599 5.057681809405475e-07 6.296048496614031 0.03665177207372783 ALASQLQDSLK ddPTM_PC-9_Lapatinib_30min_R1 2 ALASQLQDSLK 11 0 P18206;P18206-2 P18206 VCL Vinculin 0 ; 175.49 0.00091782 7462600.0 58675.0 50986.0 47423.0 49795.0 54290.0 50347.0 52024.0 42041.0 52549.0 51332.0 False True 57838.2837403228 50867.94504957049 43524.06399807384 53457.09041125049 51096.768938246736 48193.77617458927 54717.54816461301 43994.37833821611 46630.37825449819 60204.667804409415 0.9606943423095625 0.8449169624991253 0.722935041174434 0.8879226870733645 0.8487177290679176 0.8004989967083506 0.9088589001500225 0.7307469660183715 0.7745309451085943 1.0 15.877587726288695 -4.7795483384895405 4.784783904322044 0.8259569966801046 0.9682307909502157 0.17399925453536658 0.08034691849232269 0.26719551932695945 14.523398161065938 0.019055670266001898 0.12407795930850316 1.6613137574641046e-05 4.7795483384895405 0.1422737942701111 ALCHTTS(ph)SPLPGDVK ddPTM_PC-9_Lapatinib_30min_R1 1 ALCHTTSSPLPGDVK 15 0 Q9H6S1 Q9H6S1 AZI2 5-azacytidine-induced protein 2 1 ALCHT(0.002)T(0.01)S(0.921)S(0.067)PLPGDVK 94.639 0.0016965 2775500.0 74618.0 78752.0 92107.0 58612.0 77409.0 81590.0 69844.0 89348.0 73337.0 65651.0 True False 73553.93363673474 78569.6545825083 84534.31800330197 62922.522003900274 72855.95481194946 78100.58589557941 73460.18057068328 93499.43426091016 65077.01478715364 76998.68787554123 0.9552621696050911 1.020402512696143 1.0978669940446406 0.817189535821788 0.9461973550732711 1.0143106077576187 0.9540445765702202 1.2142990593818992 0.8451704383890607 1.0 16.23254624079103 ALDDISESIK ddPTM_PC-9_Lapatinib_30min_R1 1 ALDDISESIK 10 0 H0YG54;H0YGR4;F5GYG5;Q9Y3B8-2;Q9Y3B8-3;Q9Y3B8 H0YG54 REXO2 Oligoribonuclease, mitochondrial 0 106.18 0.010845 1924700.0 15394.0 12572.0 13481.0 14335.0 11488.0 11511.0 8715.3 8835.7 12593.0 12063.0 False True 15174.478737086143 12542.890306421385 12372.644218164885 15389.243720158163 10812.298426276999 11018.701363451593 9166.535589709592 9246.23887830869 11174.643729831128 14148.07347706286 1.0725473515307447 0.8865440462092714 0.8745108822217854 1.0877271555811123 0.7642240792575832 0.7788128455309009 0.6478999140462879 0.6535334222923621 0.7898350081336293 1.0 13.78831799625951 -6.356281891841481 7.4344948771997865 0.7478854482275195 0.9656864084868533 0.4407169394034154 0.11234144517653706 0.24429837130677626 16.830660885630163 0.0341435565384827 0.03872773524804187 4.4026900096074186e-07 6.356281891841481 0.21780096025933382 ALDEGDIALLK ddPTM_PC-9_Lapatinib_30min_R1 2 ALDEGDIALLK 11 0 P35998;C9JLS9 P35998 PSMC2 26S protease regulatory subunit 7 0 ; 161.76 0.0017727999999999997 3964600.0 28241.0 31842.0 32794.0 29345.0 33544.0 28589.0 26583.0 26207.0 30198.0 24844.0 False True 27838.278161234884 31768.27180536667 30097.803908500788 31503.129192050314 31571.007870041394 27366.31511421403 27959.33766838203 27424.67289335718 26796.783240962486 29138.252297450847 0.955385994913302 1.0902600293616755 1.032930993981883 1.0811605607109922 1.083490099123185 0.939188625139613 0.9595406540847354 0.9411914144128823 0.9196427763550801 1.0 14.830626727184699 -6.768989348687778 24.999421725975907 0.9487138868114359 1.0518908141451302 0.5818057393774996 0.04091457480412326 115.11354761844024 381161.1337769667 0.013780614496616708 0.01238569856916142 1.7022002552851575e-07 6.768989348687778 0.10317692733369432 ALDFIASK ddPTM_PC-9_AZD4547_30min_R2 2 ALDFIASK 8 0 O43707;G3V2E8;P12814-4;P12814-3;P12814;P12814-2;H9KV75;Q08043;G3V2N5;A0A087WSZ2;G3V2W4;G3V2X9;G3V5M4 O43707;P12814-4 ACTN4;ACTN1;ACTN3 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-3 0 ; 101.64 0.020839 4493900.0 47529.0 46981.0 54532.0 78269.0 62084.0 62924.0 49395.0 65479.0 50794.0 57536.0 False True 62642.23333538555 62166.68948647142 53808.87004942417 60225.291293995615 53464.708247846625 58989.35233278671 53791.05930920565 55360.72510773186 53478.86714199378 55521.68215259544 1.128248116892785 1.119683105342754 0.9691505725913746 1.0847166180677452 0.9629518806887832 1.0624561440818876 0.9688297836756214 0.9971010056139653 0.963206896271853 1.0 15.760763657776213 -1.5228787452803587 0.4403912178662685 0.9874092208326951 4.340922308422573 0.5370655916968041 0.042997402811631856 60.951378713500596 0.7497925625438532 0.02577220344952193 182.64950948702364 0.029999999999998538 1.5228787452803587 3.3535130875898775 ALDFIASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALDFIASK 8 0 O43707;G3V2E8;P12814-4;P12814-3;P12814;P12814-2;H9KV75;Q08043;G3V2N5;A0A087WSZ2;G3V2W4;G3V2X9;G3V5M4 O43707;P12814-4 ACTN4;ACTN1;ACTN3 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-3 0 ; 123.72 0.01514 7615500.0 91215.0 82112.0 97887.0 100808.0 110584.0 99036.0 104737.0 91143.0 84506.0 83025.0 False True 106655.89792162964 90263.53670069705 100220.99731851483 95160.05458394565 88915.85903388596 93842.377817086 94815.553129786 88750.59282399109 85741.74038035478 98076.77527446151 1.0874735392059947 0.9203354866440131 1.021862689082638 0.9702608422600191 0.9065944387451635 0.956825686351067 0.9667482731202245 0.9049093689676102 0.8742308272311367 1.0 16.58162392411623 ALDFIASK ddPTM_PC-9_Lapatinib_30min_R1 2 ALDFIASK 8 0 O43707;G3V2E8;P12814-4;P12814-3;P12814;P12814-2;H9KV75;Q08043;G3V2N5;A0A087WSZ2;G3V2W4;G3V2X9;G3V5M4 O43707;P12814-4 ACTN4;ACTN1;ACTN3 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-3 0 ; 138.54 0.013563999999999998 29397000.0 202670.0 192018.0 203162.0 208790.0 219084.0 199850.0 228413.0 203971.0 184004.0 198615.0 False True 199779.8886348737 191573.39411855093 186458.804587999 224145.1131030218 206197.90985571616 191302.88137310397 240239.10750660734 213448.23729274495 163279.5318719804 232945.3381121479 0.8576256140343653 0.8223963427262103 0.8004401637702289 0.9622219312030647 0.885177233108848 0.8212350713840179 1.0313110768971387 0.9163018200861509 0.7009349626622363 1.0 17.829631932808553 -5.742881968443902 24.976104092896225 0.9002321583493236 0.8263782612371968 0.13152959685951404 0.08893137082795739 527.0017654622293 709276.7817287846 0.024013878652169845 0.041499852617862515 1.8076653423890455e-06 5.742881968443902 -0.07385389711212675 ALDIDS(ph)DEESEPK ddPTM_PC-9_Lapatinib_30min_R1 2 ALDIDSDEESEPK 13 0 Q96DR7;Q96DR7-4;Q96DR7-3 Q96DR7 ARHGEF26 Rho guanine nucleotide exchange factor 26 1 ALDIDS(0.794)DEES(0.206)EPK;ALDIDS(1)DEESEPK 127.78 0.00089456 0.0 10981.9 16330.5 11233.0 14083.1 13643.1 11478.2 12775.099999999999 15194.8 14719.2 12373.4 True False 10825.296092166189 16292.687730592934 10309.466100633932 15118.818153844388 12840.639681366616 10987.304142991065 13436.532168955622 15900.805879344587 13061.368695952537 14512.125703480868 0.7459483409497784 1.1226947770087867 0.7104035832711338 1.041805898237086 0.8848214206335513 0.7571119743233521 0.9258831161952205 1.0956910244741493 0.9000313918738759 1.0 13.824971237152216 -7.533627217454949 24.145732840426962 1.0008741965803158 0.8846282776716667 0.14931688287659872 0.12899129534894826 280.19271401812597 629421.3410186488 0.05697837189001244 0.03294308783802398 2.9266634411524455e-08 7.533627217454949 -0.1162459189086491 ALDLAALSCNSNGYT(ph)S(ph)MYSAMSPFSK ddPTM_PC-9_Lapatinib_30min_R1 1 ALDLAALSCNSNGYTSMYSAMSPFSK 26 0 Q13972-3;Q13972 Q13972-3 RASGRF1 Ras-specific guanine nucleotide-releasing factor 1 2 ALDLAALS(0.001)CNS(0.003)NGY(0.447)T(0.477)S(0.477)MY(0.18)S(0.187)AMS(0.187)PFS(0.041)K 46.353 0.020492 5446600.0 10170.0 10961.0 9223.5 10326.0 11563.0 12326.0 8709.3 13473.0 12901.0 7041.5 True False 10024.97393505041 10935.620477941828 8465.179433739613 11085.408486526214 10882.887073732678 11798.84571330939 9160.22493906781 14099.004765604648 11447.953526447347 8258.613892791021 1.2138809327072733 1.3241472019278655 1.025012132015144 1.342284386996553 1.3177619410482908 1.4286714291860347 1.109172199836562 1.7071877858234452 1.3861834049949124 1.0 13.011683947928812 -5.953783422837504 24.9787566382084 1.352364310381623 1.1983800564525056 0.09084297302176536 0.1906516796089466 264.00104997356385 142683.34659930045 0.05210044361959714 0.07727741472358803 1.1122862720867081e-06 5.953783422837504 -0.1539842539291174 ALDLDSSCK ddPTM_PC-9_Lapatinib_30min_R1 1 ALDLDSSCK 9 0 P31948-2;P31948;P31948-3;H0YGI8 P31948-2 STIP1 Stress-induced-phosphoprotein 1 0 107.15 0.004287699999999999 0.0 62746.0 54801.0 60062.0 65786.0 58802.0 55856.0 66107.0 49406.0 57206.0 57196.0 False True 61851.230533792856 54674.11165146341 55123.934206024685 70624.12189566273 55343.381969179994 53467.16908669551 69529.69699596478 51701.58312547048 50762.85787411415 67082.25239112048 0.9220207779126385 0.8150309463774132 0.8217364838113473 1.052798905497262 0.8250078075271318 0.7970389660585224 1.0364842341693385 0.7707192481258143 0.7567256027442738 1.0 16.0336435099983 ALDLLDK ddPTM_PC-9_Lapatinib_30min_R1 1 ALDLLDK 7 0 P28482 P28482 MAPK1 Mitogen-activated protein kinase 1 0 91.065 0.026376 0.0 19691.0 16277.0 19052.0 17970.0 16943.0 15252.0 14964.0 16241.0 16524.0 17518.0 False True 19410.202729112847 16239.311606555895 17485.618102846776 19291.57374616268 15946.44605121964 14599.707514148526 15738.762700585678 16995.61615068545 14662.893114565986 20545.962958732263 0.944721002763382 0.7903894131987621 0.8510488477939747 0.9389471685951594 0.776135247749107 0.7105876489446062 0.7660270162171459 0.8271997854187761 0.7136629781732422 1.0 14.326567328610917 -6.289981750896284 24.054066651936637 0.7842326070922263 0.8726255494172488 0.161800402390053 0.08719349857961636 725.9703094461796 611808.5575082693 0.025720865051772877 0.029171249805404222 5.128829349380607e-07 6.289981750896284 0.08839294232502248 ALDMLQMASS(ph)PIASSSNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALDMLQMASSPIASSSNR 18 0 Q96MY7;Q96MY7-2 Q96MY7 FAM161B Protein FAM161B 1 ALDMLQMAS(0.116)S(0.884)PIASSSNR 90.259 0.0011952 2746600.0 1552.8 846.41 12887.0 4565.1 10577.0 9077.8 5409.1 5078.3 9900.1 4739.5 True False 1815.6583708020235 930.4359910711831 13194.274954219667 4309.332247253889 8504.512777629807 8601.744187446426 4896.710889507294 4945.000005903618 10044.8702333509 5598.733832138642 0.3242980333123759 0.16618685920201512 2.3566533701745254 0.7696976452991661 1.5190064454950514 1.536373123878381 0.8746104094819623 0.8832354161074119 1.7941324832571819 1.0 12.450884879576133 -5.20983695690652 24.96808372546712 1.3137166744139765 0.2452407072330074 0.46621171478182033 0.4685338778002386 290.3969694713226 140508.85683525284 0.11368866600985958 0.30079140143405975 6.168265277819984e-06 5.20983695690652 -1.0684759671809692 ALDS(ph)NSLENDDLSAPGR ddPTM_PC-9_AZD4547_30min_R2 2 ALDSNSLENDDLSAPGR 17 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 ALDS(0.999)NS(0.001)LENDDLSAPGR;ALDS(0.999)NS(0.001)LENDDLSAPGR 195.46 2.0412e-53 2881200.0 7565.7 11254.1 11578.8 11548.5 10798.3 12106.8 10009.3 14455.8 10467.900000000001 11145.3 True False 9971.435223664012 14891.767739079598 11425.25754654648 8886.17174754639 9299.142437225733 11349.759882121003 10900.108309416586 12221.988271237342 11021.211823358606 10755.106439365296 0.927134964203336 1.3846229995989165 1.0623100395109368 0.8262281547509074 0.8646257933059113 1.055290335442817 1.0134821417964366 1.1363893365576596 1.0247422362106362 1.0 13.392734182207644 -5.515694602301519 24.995452325341585 0.9892538343922787 1.172775876713617 0.2010413321626877 0.13240082148849858 441.9632584343893 1537700.5395553154 0.03577032093922442 0.06530893872628755 3.0500390359119558e-06 5.515694602301519 0.18352204232133829 ALDS(ph)NSLENDDLSAPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALDSNSLENDDLSAPGR 17 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 ALDS(0.993)NS(0.007)LENDDLSAPGR;ALDS(0.912)NS(0.088)LENDDLSAPGR 156.0 3.7894e-17 0.0 5559.299999999999 7424.8 7538.3 6463.0 9035.3 9841.7 10836.099999999999 8202.5 9954.0 9724.900000000001 True False 6500.379688819993 8161.885075206249 7718.041661161948 6100.899063328709 7264.897825443753 9325.583926677327 9809.626161429802 7987.193066267141 10099.558418882121 11487.947387733959 0.5658434417762612 0.710473751291806 0.6718381796736589 0.5310695511926552 0.6323930272522585 0.8117711208039258 0.8539059094145789 0.6952672045482483 0.8791438607793187 1.0 13.487833426612996 -6.774057793235542 5.0928051988177385 0.8312899723104347 0.6238033396453154 0.63832595949442 0.08460944722184978 0.13011009207032784 9.275234611516682 0.029169971852398637 0.026948482726816752 1.6824501560655382e-07 6.774057793235542 -0.20748663266511924 ALDS(ph)NSLENDDLSAPGR ddPTM_PC-9_Lapatinib_30min_R1 1 ALDSNSLENDDLSAPGR 17 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 ALDS(0.993)NS(0.007)LENDDLSAPGR 99.81299999999999 0.0012209000000000002 1446100.0 996.76 2645.3 2123.2 2584.2 3313.3 4988.6 4622.6 5601.2 4478.4 6225.9 True False 982.5460196166024 2639.1749703767464 1948.6386917890122 2774.2506886384886 3118.4182081984304 4775.24920699458 4861.935609444487 5861.452200185909 3973.995432357318 7302.038519509709 0.1345577699968878 0.36142988883520055 0.26686228600172496 0.3799282462323636 0.4270613199131432 0.6539611088377567 0.665832643371339 0.8027145001392669 0.5442309598531329 1.0 12.834083563919554 -6.614530393244615 0.2772014937723522 0.9924725063039329 2.2200300445858083e-13 0.8464770370543456 0.09725035214641616 1.146673564036308 0.17399804098396723 0.1490764104436285 0.3855420303777895 2.429235430810705e-07 6.614530393244615 -0.9924725063037109 down ALDSNS(ph)LENDDLSAPGR ddPTM_PC-9_AZD4547_30min_R2 1 ALDSNSLENDDLSAPGR 17 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 ALDS(0.04)NS(0.96)LENDDLSAPGR 103.45 0.00086403 2916900.0 11655.0 13533.0 8071.0 8303.1 9577.1 11543.0 11529.0 9030.8 7880.8 10645.0 True False 15361.047560940036 17907.27759776118 7963.9732665022875 6388.948576616221 8247.484977779333 10821.214385248193 12555.05866536759 7635.29736713916 8297.362999027931 10272.32179008583 1.4953822392680016 1.7432551241769028 0.7752846366425739 0.6219575970431936 0.8028842112149625 1.0534341316772335 1.2222220956400438 0.7432883746407016 0.8077397854724528 1.0 13.326474681601422 -5.2625312990306865 24.99819815801251 0.8758649487914291 1.6193187250079657 0.745574161055254 0.17313384868521745 46.94028145581519 1074672.5465729672 0.04912558263564731 0.11247537288832138 5.463471739425268e-06 5.2625312990306865 0.7434537762165366 ALDSNS(ph)LENDDLSAPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALDSNSLENDDLSAPGR 17 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 ALDS(0.035)NS(0.964)LENDDLS(0.001)APGR;ALDS(0.035)NS(0.921)LENDDLS(0.044)APGR 120.79 8.0674e-05 5119900.0 18559.9 25705.0 21557.7 20210.3 21342.9 20759.3 24839.0 19960.2 19923.9 17779.2 True False 21701.72449526561 28256.822521573205 22071.717326032518 19077.98241367665 17160.911956289612 19670.64576334096 22486.07010121307 19436.26589958005 20215.249345184395 21002.428219930236 1.0332959726376676 1.3454074084042777 1.0509126418576487 0.9083703186078559 0.8170918036993827 0.9365891199511167 1.0706414451579904 0.9254294644433552 0.9625196255164987 1.0 14.358268515932828 -5.508259216158141 6.060053705564272 0.9442394959267456 1.1930224531442353 0.5230571292009082 0.09280492622987216 0.1145309790565614 16.282104480906593 0.02464653753326723 0.048092743293075876 3.1027071310390098e-06 5.508259216158141 0.24878295721748966 ALDSNS(ph)LENDDLSAPGR ddPTM_PC-9_Lapatinib_30min_R1 2 ALDSNSLENDDLSAPGR 17 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 ALDS(0.036)NS(0.964)LENDDLSAPGR;ALDS(0.179)NS(0.821)LENDDLSAPGR 123.43 4.4758e-05 2095400.0 12009.8 18297.4 15454.900000000001 15065.8 16924.2 14164.2 17588.8 15820.599999999999 13050.8 14977.599999999999 True False 11838.538049672412 18255.033494488915 14184.25777963923 16173.789190035504 15928.751830257406 13558.430184362882 18499.462001340642 16555.682831939805 11580.881472983418 17566.458203602484 0.6739285695761138 1.039198299560763 0.8074625866658971 0.9207199882056262 0.9067708268585855 0.7718363045763177 1.053112800937119 0.942459922202451 0.6592610382102204 1.0 14.100535720173891 -4.734913342833955 24.675152957492426 0.8970258532905664 0.6739272532086819 0.24962451719481926 0.11752726199853988 3392.504142109376 3155592.924783324 0.02787332894461725 2.268902105926738 1.8411393374753978e-05 4.734913342833955 -0.22309860008188453 ALDSNS(ph)LENDDLSAPGREPGHFNPESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALDSNSLENDDLSAPGREPGHFNPESR 27 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 ALDS(0.086)NS(0.914)LENDDLSAPGREPGHFNPESR;ALDS(0.285)NS(0.702)LENDDLS(0.012)APGREPGHFNPESR 80.415 9.4109e-06 13851200.0 9716.6 12596.1 11732.7 12534.9 13896.5 13157.6 10472.9 14184.8 10919.22 7307.8 True False 11361.428468402202 13846.557563275173 12012.452064512525 11832.610191694112 11173.580581859944 12467.592293368994 9480.831094770088 13812.464030037936 11078.892935365277 8632.646291487024 1.3161003109331761 1.603976011032652 1.39151445094634 1.3706816881125654 1.294340136798913 1.4442375920885064 1.0982531630097587 1.6000266388371458 1.2833715828587333 1.0 13.075587162303107 -13.16198123549781 0.23315441889776098 3.98378826800472e-14 1.4293484657741122 0.40303648607548204 0.140708847277254 81.4953702371504 1.4412516293575892 39.29584935290396 0.23548895335132433 6.886820514925206e-14 13.16198123549781 1.4293484657740725 ALDSNS(ph)LENDDLSAPGREPGHFNPESR ddPTM_PC-9_Lapatinib_30min_R1 1 ALDSNSLENDDLSAPGREPGHFNPESR 27 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 ALDS(0.11)NS(0.89)LENDDLSAPGREPGHFNPESR 70.766 8.7872e-05 8484200.0 10555.0 9254.2 14283.0 7685.9 12010.0 8299.6 5888.7 9323.2 9794.3 4902.6 True False 10404.48376445006 9232.77246847636 13108.706873974406 8251.146725410788 11303.595412568486 7944.645455312555 6193.58807236961 9756.389908014948 8691.162795448668 5750.007877696129 1.8094729582559899 1.6056973598748667 2.279771985151907 1.4349800732302296 1.965839987178857 1.3816755775464706 1.077144275992055 1.696761137642835 1.511504502308783 1.0 12.489348217259161 -6.776425720496117 23.76004715471819 1.3609473025551249 1.811540861142657 0.4308112720368331 0.2781937585919115 138.64069878890288 219805.22475209075 0.09526557819071625 0.08440307791380966 1.6733018048962045e-07 6.776425720496117 0.45059355858753225 ALDSNSLENDDLS(ph)APGREPGHFNPESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALDSNSLENDDLSAPGREPGHFNPESR 27 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 ALDS(0.277)NS(0.323)LENDDLS(0.399)APGREPGHFNPES(0.001)R 43.494 0.023354 2826000.0 0.0 0.0 971.03 1014.2 703.16 1107.6 2000.1 0.0 763.87 0.0 True False 0.0 0.0 994.1830378517823 957.3776620807643 565.3808456762948 1049.5155061816363 1810.6360485299833 0.0 775.040153649938 0.0 0.0 ALDTMNFDVIK ddPTM_PC-9_Lapatinib_30min_R1 3 ALDTMNFDVIK 11 0 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YBN4;Q13310-3;E5RGH3;Q13310-2;Q13310;B1ANR0;E5RH24;E5RJB9;B1ANR1;H0YEQ8 A0A087WTT1 PABPC1;PABPC4 Polyadenylate-binding protein;Polyadenylate-binding protein 1;Polyadenylate-binding protein 4 0 ;; 179.67 0.0087547 9212800.0 54357.0 53735.0 57565.0 47453.0 55949.0 51488.0 53203.0 49119.0 49394.0 48941.0 False True 53581.859212147065 53610.579908968546 52832.22790732594 50942.85191856754 52658.189819966225 49285.9782643902 55957.59101572168 51401.248057725454 43830.72757812107 57400.38664021665 0.9334755800164907 0.9339759372179414 0.9204158891555252 0.8875001528800723 0.9173838871508945 0.8586349526408725 0.9748643570375517 0.8954860945433424 0.7635963822482649 1.0 15.808772834256066 -5.578156646049073 4.150749230324021 0.8975054137719369 0.9327050328344164 0.0499693041422401 0.060371425375454646 0.6768377997974531 24.046602135513318 0.01630343329169581 0.03041353013208018 2.641455836506722e-06 5.578156646049073 0.03519961906247948 ALDVS(ph)ASDDEIAR ddPTM_PC-9_Lapatinib_30min_R1 2 ALDVSASDDEIAR 13 0 H7C393;C9JIF9;P13798;C9JLK2;H7C1U0 H7C393 APEH Acylamino-acid-releasing enzyme 1 ALDVS(0.5)AS(0.5)DDEIAR;ALDVS(0.5)AS(0.5)DDEIAR 139.48 6.8597e-05 13822200.0 26443.0 24184.0 26740.0 21915.0 23508.0 21965.2 21587.3 22981.8 29313.0 17434.800000000003 True False 26065.917970947707 24128.003433860536 24541.540419384975 23526.70220629691 22125.305658506248 21025.799599382055 22704.98476652989 24049.6183271857 26011.461260425636 20448.3819495893 1.2747178742654126 1.1799468287193815 1.2001702863281016 1.1505410190545389 1.082007647991465 1.028237816137054 1.1103560576334948 1.176113512867395 1.27205474372255 1.0 14.319699068894568 -5.2916977006982995 1.1671117520587937 1.1180142902355719 1.2651183944953683 0.30212703982392397 0.07378030175521666 1.114634052340185 2.2291883202911404 0.025657855360100394 0.16145387113826704 5.10860470824108e-06 5.2916977006982995 0.14710410425979648 ALDVSAS(ph)DDEIAR ddPTM_PC-9_AZD4547_30min_R2 1 ALDVSASDDEIAR 13 0 H7C393;C9JIF9;P13798;C9JLK2;H7C1U0 H7C393 APEH Acylamino-acid-releasing enzyme 1 ALDVS(0.227)AS(0.773)DDEIAR 155.14 0.00018071 6712000.0 11926.0 14350.0 19383.0 19328.0 18231.0 15631.0 13857.0 18068.0 12406.0 18503.0 True False 15718.21992378987 18988.3568704554 19125.968755372774 14872.228214623248 15699.940339966688 14653.591099004987 15090.246155434013 15276.00576133568 13061.755832649022 17855.21560187489 0.8803153249036867 1.063462760341103 1.0711698576949387 0.8329346755724186 0.8792915577181892 0.8206896755403101 0.8451449980726897 0.8555486588317432 0.7315372787364981 1.0 14.124057934133061 -5.7717497697748765 24.988956841542688 0.8456714524776234 1.0108306600900792 0.43844556612985497 0.07893263109724825 163.53856060324765 396363.3780406519 0.021258869324221243 0.03192963699172274 1.6914152044398554e-06 5.7717497697748765 0.16515920761245573 ALDVSAS(ph)DDEIAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALDVSASDDEIAR 13 0 H7C393;C9JIF9;P13798;C9JLK2;H7C1U0 H7C393 APEH Acylamino-acid-releasing enzyme 1 ALDVS(0.151)AS(0.849)DDEIAR;ALDVS(0.491)AS(0.509)DDEIAR 96.135 0.0033399000000000002 12147700.0 30936.0 34025.0 33196.0 35561.0 37308.0 35493.0 36210.0 35744.0 29070.0 24759.5 True False 36172.8537861485 37402.77713660876 33987.518536531046 33568.63246031756 29997.765217718905 33631.68459814446 32779.926662302234 34805.75787389852 29495.093754963153 29248.201353905857 1.2367548126619388 1.278806060038763 1.1620379019304137 1.1477161297590268 1.0256276909045878 1.1498718909651249 1.120750170776732 1.1900136166578494 1.008441284921075 1.0 14.836060287063045 -1.5228787452803376 0.20666647478556077 1.0338698493790046 2.1949764005051144 0.5701672483342786 0.05918448202887018 42.13765227429981 0.5195299361404471 0.10709352174043513 16.001199903917623 0.029999999999999995 1.5228787452803376 1.1611065511261098 ALEATTEHIR ddPTM_PC-9_Lapatinib_30min_R1 2 ALEATTEHIR 10 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 ; 178.84 3.4233e-27 2682500.0 26173.0 27423.0 27707.0 27225.0 31809.0 30887.0 30258.0 27341.0 32533.0 24313.3 False True 25799.768220459646 27359.50372836409 25429.03741211291 29227.217319937645 29938.057158900156 29566.03501111367 31824.611186468945 28611.362673227704 28868.790952322393 28515.821509564168 0.9047527602109039 0.9594499572522485 0.8917518789905472 1.0249474071835831 1.0498753174219082 1.0368291511853256 1.1160334685008115 1.0033504615545266 1.012378021185181 1.0 14.799474975318692 -5.832806967377506 6.133746986841466 1.0399695085224825 0.9230230576641902 0.6952888071448884 0.03514182550726937 0.11062013194998382 7.190727029999874 0.0099885436316696 0.015075263222448553 1.469579322359469e-06 5.832806967377506 -0.11694645085829225 ALEAVFGK ddPTM_PC-9_Lapatinib_30min_R1 2 ALEAVFGK 8 0 P38159;P38159-2;H0Y6E7;H3BT71;H3BR27;P38159-3;H3BNC1 P38159 RBMX RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed 0 ; 135.84 8.0844e-08 6150700.0 98546.0 84057.0 92643.0 93945.0 87352.0 84202.0 86968.0 71863.0 91586.0 79226.0 False True 97140.71596887692 83862.37118094668 85026.25015232153 100854.02869133299 82214.12710063969 80600.87674444885 91470.77750230796 75202.0173287796 81270.62023666436 92920.1085379907 1.0454218951881724 0.90252123572003 0.9150468234500422 1.085384318617089 0.8847829430486099 0.8674212504981621 0.9844023962252457 0.8093190861699543 0.8746289852151495 1.0 16.503703218878364 ALEEEEDDR ddPTM_PC-9_AZD4547_30min_R2 2 ALEEEEDDR 9 0 Q9BTC0 Q9BTC0 DIDO1 Death-inducer obliterator 1 0 ; 101.28 0.016347 19928600.0 127102.0 127824.0 171465.0 250630.0 193853.0 155411.0 154449.0 198754.0 146814.0 153213.0 False True 167517.7921141654 169140.60826544202 169191.26206675937 192851.1256948998 166939.85709635002 145693.12560216617 168194.66179264084 168041.1362125587 154574.28831327858 147849.0595044074 1.1330325175938754 1.1440086858340814 1.1443512906601598 1.3043784406971548 1.1291235646404199 0.9854180073280956 1.1376106304391265 1.1365722364135118 1.0454871260690752 1.0 17.173765540670544 -6.524350735607542 24.999732241676703 1.072443792871785 1.1811984265574496 0.42980396454195036 0.06491647345516321 52.851511230342524 897583.7108540784 0.021751074296155783 0.021913155277254983 2.9898490634701754e-07 6.524350735607542 0.10875463368566463 ALEEELAGLK ddPTM_PC-9_Lapatinib_30min_R1 1 ALEEELAGLK 10 0 O95347-2;O95347 O95347-2 SMC2 Structural maintenance of chromosomes protein 2 0 118.18 0.0041238 903710.0 10250.0 10522.0 9637.5 10168.0 9392.2 9305.1 11763.0 8470.9 8831.6 8936.5 False True 10103.833120380212 10497.636955469758 8845.141951825828 10915.788639453658 8839.76926177567 8907.14256424754 12372.030583198957 8864.48893854082 7836.89220712909 10481.162117862239 0.963999316751434 1.0015718521879784 0.8439085143766388 1.0414673980522369 0.8433959099545584 0.84982394739108 1.1804063751780212 0.8457543962070535 0.7477121447986457 1.0 13.355511066723126 -5.184172745479444 24.997445435640834 0.9220777101012045 0.9827857751041016 0.04342842913194078 0.11896042966120604 472.6269461587943 152899.85082623307 0.03036336062169515 0.08033389405501894 6.543758369988912e-06 5.184172745479444 0.06070806500289705 ALEENNNFSK ddPTM_PC-9_Lapatinib_30min_R1 1 ALEENNNFSK 10 0 E5RGX5;Q93045;Q93045-2 E5RGX5 STMN2 Stathmin;Stathmin-2 0 91.65799999999999 0.029695 0.0 21022.0 14698.0 18053.0 19223.0 21065.0 18214.0 18154.0 11660.0 21492.0 16357.0 False True 20722.222425037344 14663.967684042427 16568.752026595244 20636.723546048168 19825.998115383445 17435.029678907773 19093.925291795804 12201.766166922755 19071.34463920676 19184.28565566751 1.0801664861008515 0.7643739228679766 0.8636627041518445 1.0757097718648476 1.0334499011969391 0.9088182897108309 0.9952898760217839 0.6360292160953125 0.994112837012131 1.0 14.227637425427709 -8.478222347175386 24.999279635386348 1.0000051391896636 0.9169983757592133 0.05122178300704705 0.13291093119627123 1253.8216776039353 701907.9811133286 0.12923093862703985 0.03336728487796215 3.3248928407791606e-09 8.478222347175386 -0.08300676343045033 ALEIIPR ddPTM_PC-9_Lapatinib_30min_R1 1 ALEIIPR 7 0 Q99832-3;Q99832;Q99832-2;Q99832-4 Q99832-3 CCT7 T-complex protein 1 subunit eta 0 114.72 0.039346 4268200.0 31974.0 30307.0 30161.0 29813.0 29871.0 27057.0 27578.0 19268.0 26477.0 23882.0 False True 31518.044896686537 30236.826003556547 27681.279004826876 32005.547473252533 28114.04650864557 25899.835182947587 29005.85389980967 20163.261621292248 23494.881444829578 28009.971879235298 1.1252437179364643 1.079502190645614 0.988265148004233 1.1426483257906905 1.0037156277721015 0.9246648048992857 1.0355545526738872 0.7198601165408498 0.8388041782450734 1.0 14.773652914561007 -7.016557472844371 1.1312051598760071 0.8552135596463778 1.0781272247561657 0.46971351213531876 0.0897498068846363 0.4062280824204497 1.064383032684546 0.053435073321277934 0.03779341514596927 9.625926187768701e-08 7.016557472844371 0.22291366510978794 ALEIS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 ALEISPR 7 0 Q8IY92;Q8IY92-2 Q8IY92 SLX4 Structure-specific endonuclease subunit SLX4 1 ALEIS(1)PR 76.17 0.031649000000000004 9183200.0 14608.0 17862.0 18348.0 29869.0 26882.0 20179.0 19843.0 25646.0 19006.0 22667.0 True False 19253.040134724328 23635.54218955222 18104.69353162977 22983.1635214498 23149.89831709642 18917.203940043608 21608.988559015448 21682.999986452007 20010.61835848198 21873.43522929783 0.8802019405226447 1.0805592236327919 0.8277023403886687 1.0507340653408466 1.05835677269791 0.8648483304856216 0.987910144542446 0.9912937661208904 0.9148365653913957 1.0 14.416892193400578 -5.56855648737416 0.0023021922551864976 1.9287625853830654 3.1697668821792415e-05 0.008112845974382998 0.08359031826723201 1181842.2678839415 563.6868840119807 233175.0580712462 239087.4881509337 2.7004958401271854e-06 5.56855648737416 -1.9287308877142437 ALEIS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALEISPR 7 0 Q8IY92;Q8IY92-2 Q8IY92 SLX4 Structure-specific endonuclease subunit SLX4 1 ALEIS(1)PR 78.149 0.028754000000000002 5193900.0 22796.0 19231.0 26787.0 26010.0 24618.0 20552.0 21847.0 24032.0 20278.0 17064.0 True False 26654.912558476874 21140.126586748665 27425.703670263214 24552.744025557757 19794.279621791673 19474.216940271748 19777.494001417206 23401.185464008773 20574.527387792994 20157.568121450335 1.3223277926126664 1.0487438990347628 1.3605660913569537 1.2180409798258536 0.9819775630934332 0.9660995226675478 0.98114484258502 1.1609131281618639 1.0206849984993458 1.0 14.29903397717937 -6.239159422542618 10.525932978111987 1.0220315724985714 1.2328494072155545 0.5758979961169807 0.09198409872696292 0.48938906726614895 227.80714060666986 0.027251075947710188 0.034713560529924914 5.765547805241083e-07 6.239159422542618 0.21081783471698312 ALEIS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 ALEISPR 7 0 Q8IY92;Q8IY92-2 Q8IY92 SLX4 Structure-specific endonuclease subunit SLX4 1 ALEIS(1)PR 85.86200000000001 0.019 5659800.0 19694.0 15809.0 21345.0 15072.0 16414.0 16517.0 15709.0 14105.0 19512.0 11922.0 True False 19413.159948562716 15772.395231802067 19590.096494082725 16180.4451587181 15448.560791165628 15810.606413007552 16522.33515527268 14760.369792834079 17314.353089531098 13982.701814933549 1.3883697303642297 1.1279933907306186 1.4010236900825896 1.15717587150699 1.1048337435520894 1.1307261373565012 1.1816267967344336 1.0556164315161165 1.2382694931704357 1.0 13.771355532708819 -1.5228787452803376 0.17079701064041475 1.0303320998926164 2.223465759423316 0.41866725312946806 0.09486982249053905 61.012333952236546 0.6625997455025543 0.23510463457923822 18.61961598627068 0.029999999999999995 1.5228787452803376 1.1931336595306994 ALELDHK ddPTM_PC-9_AZD4547_30min_R2 1 ALELDHK 7 0 Q99615-2;K7EJL5;K7EN19;K7EJV7;A0A6I8PRZ0;K7EPP7;K7EJE9;A0A6I8PUC2;K7ER44;A0A6I8PLE7;A0A6I8PUD4;A0A6I8PS32;A0A6I8PR89;K7EIH8;A0A6I8PU89;K7EK03;K7ESP1;K7ELJ8;A0A6I8PU73;Q99615 Q99615-2 DNAJC7 DnaJ homolog subfamily C member 7 0 116.9 0.00031474 0.0 9866.7 10579.0 15332.0 18584.0 17527.0 15078.0 12977.0 15930.0 12163.0 13103.0 False True 13004.105359890778 13998.454866379627 15128.68766224916 14299.745919937837 15093.678588042145 14135.17027642486 14131.927860219894 13468.384534983257 12805.91134874336 12644.267958242797 1.0284585396984887 1.1070988777372466 1.1964858473587447 1.1309271495322775 1.1937170770097907 1.1179113194299353 1.117654885746651 1.065177088896097 1.0127839263636602 1.0 13.62619589392631 -7.987163139833628 1.6620804606075255 1.0000403751225717 1.1340174200344162 0.550477554851347 0.04426108125691898 0.2993197413497286 1.4897750828577 0.04032344941548621 0.01350773178092632 1.0299991354373075e-08 7.987163139833628 0.13397704491184448 ALELDHK ddPTM_PC-9_Lapatinib_30min_R1 1 ALELDHK 7 0 Q99615-2;K7EJL5;K7EN19;K7EJV7;A0A6I8PRZ0;K7EPP7;K7EJE9;A0A6I8PUC2;K7ER44;A0A6I8PLE7;A0A6I8PUD4;A0A6I8PS32;A0A6I8PR89;K7EIH8;A0A6I8PU89;K7EK03;K7ESP1;K7ELJ8;A0A6I8PU73;Q99615 Q99615-2 DNAJC7 DnaJ homolog subfamily C member 7 0 99.375 0.0099553 3244500.0 25409.0 23296.0 26761.0 26845.0 28650.0 25076.0 26421.0 19798.0 23861.0 25280.0 False True 25046.663000560067 23242.059543301973 24560.813880447324 28819.27085229481 26964.863328067193 24003.557935011042 27788.950101054117 20717.887356152387 21173.52291253081 29649.61431651739 0.844755103158523 0.783890788432757 0.8283687476759127 0.9719947971208514 0.909450728100886 0.8095740362342249 0.9372449099809463 0.6987573981564658 0.7141247331752081 1.0 14.855725717802459 -10.143185104727722 7.768613887628508 0.9999999975703711 0.8362872097590965 0.2591352553943739 0.08449462263974032 0.0 0.0 0.08737705019233415 0.021192047482228804 7.191424002408696e-11 10.143185104727722 -0.16371278781127452 ALELDSNLYR ddPTM_PC-9_Lapatinib_30min_R1 1 ALELDSNLYR 10 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 96.34200000000001 0.025654000000000003 8063400.0 70800.0 62939.0 64994.0 66945.0 75349.0 73650.0 66552.0 75269.0 57013.0 62138.0 False True 69790.37901687014 62793.26861246064 59650.444204095234 71868.3586219734 70917.11996183376 70500.16118653555 69997.73691856313 78766.27252299381 50591.595566494274 72878.47050631943 0.9576268345370734 0.8616161697166205 0.8184919879585403 0.986139776571485 0.9730873805273452 0.9673660917516422 0.9604720904851247 1.0807893192018052 0.6941912366575721 1.0 16.15320506130052 -5.775170743921008 24.962124094705754 0.9569938594727107 0.8774821001776529 0.09983236591059075 0.09880434469596501 467.86648899916287 850529.4774767595 0.026646397038928682 0.03975885609212682 1.678144122009938e-06 5.775170743921008 -0.07951175929505772 ALELDSNNEK ddPTM_PC-9_Lapatinib_30min_R1 2 ALELDSNNEK 10 0 Q02790 Q02790 FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed 0 ; 150.81 0.00074871 14315400.0 55064.0 47124.0 56974.0 44561.0 44821.0 46792.0 54912.0 47854.0 48483.0 45841.0 False True 54278.77726249913 47014.88727328993 52289.81764599998 47838.16459113833 42184.71690147643 44790.81523747956 57755.07467352046 50077.47153961589 43022.33399137637 53764.555770707004 1.009564321408795 0.8744587693386179 0.9725704396964344 0.8897714099072386 0.7846194634506826 0.8330918873114417 1.0742221124235094 0.9314216554338207 0.8001988182485196 1.0 15.714367770443886 -10.090318381295482 15.313442020485892 0.9999988221950012 0.9079385990946742 0.09088927862373042 0.08750723891074459 0.0 0.0 0.0870994164344639 0.02112471140523256 8.122348484611696e-11 10.090318381295482 -0.09206022310032702 ALELENDR ddPTM_PC-9_AZD4547_30min_R2 1 ALELENDR 8 0 Q03252 Q03252 LMNB2 Lamin-B2 0 98.62899999999999 0.021449 0.0 14947.0 19153.0 37984.0 68816.0 39276.0 21737.0 19398.0 42121.0 24716.0 27381.0 False True 19699.8350830863 25343.83269267123 37480.307341695276 52951.53439660156 33823.20535310907 20377.781953750313 21124.384421094677 35612.16729428937 26022.437301285925 26422.39952412778 0.7455732801669761 0.9591798303378294 1.4185050569487414 2.0040395781711093 1.280095902047927 0.7712313158818983 0.7994877377357349 1.3478021654229357 0.984862759248015 1.0 14.689473869009502 -6.641339782288629 8.682059090153384 0.9918326995844606 1.314508128252119 0.16142505441285493 0.33894864314378453 0.5285971902189877 37.86629005481293 0.12431709205847706 0.12421865261639084 2.2838113013364206e-07 6.641339782288629 0.3226754286676583 ALELENDR ddPTM_PC-9_Lapatinib_30min_R1 2 ALELENDR 8 0 Q03252 Q03252 LMNB2 Lamin-B2 0 ; 113.26 0.017125 5385400.0 36468.0 32985.0 44396.0 34286.0 42272.0 41295.0 40031.0 32821.0 40559.0 29821.0 False True 35947.959632587874 32908.62525909236 40745.9322535159 36807.50681474314 39785.644069949645 39528.909113346686 42103.609306812665 34345.983478951275 35990.818314795586 34975.52011601521 1.0278034326107817 0.9409045283653575 1.1649843124093653 1.0523791123806352 1.1375283037387025 1.1301878851902045 1.2038022355965916 0.982000649740855 1.0290288234574523 1.0 15.094057891213001 -1.6012997696914422 18.601410379196814 1.0727123577192097 0.005343803171427908 0.0 0.08272286335416705 0.0 0.0 0.019514780327501324 0.0 0.02504380019958368 1.6012997696914422 -1.0673685545477818 ALELTGLK ddPTM_PC-9_AZD4547_30min_R2 1 ALELTGLK 8 0 P19338 P19338 NCL Nucleolin 0 105.57 0.011068000000000001 0.0 13092.0 15256.0 16374.0 20161.0 17476.0 14639.0 13536.0 16164.0 13886.0 11714.0 False True 17254.983669483216 20187.203652659748 16156.870061418464 15513.192934344965 15049.759057718064 13723.621015823297 14740.677777293411 13666.225211768327 14619.98561116914 11303.89642546411 1.5264633556455085 1.7858624046823668 1.4293186573279402 1.372375714572069 1.3313780037665337 1.2140611077175398 1.3040351063450402 1.2089835838359804 1.2933580652981682 1.0 13.464532531371283 -1.5228787452858386 0.1659147288081099 1.0014213202669708 3.7364560000715006 0.7549465401145363 0.09830074719654873 28.634572487200458 0.30455257460263324 0.2672116612885892 19.310807175813146 0.029999999999620004 1.5228787452858386 2.7350346798045297 ALELTGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALELTGLK 8 0 P19338 P19338 NCL Nucleolin 0 ; 132.08 0.017289 11918400.0 50419.0 50627.0 51943.0 61607.0 67958.0 62599.0 57996.0 62369.0 57200.0 48391.0 False True 58953.94087935808 55652.913977813165 53181.51811492448 58155.359522588864 54642.11774058487 59316.198240758626 52502.19902532117 60731.87983541788 58036.44178823158 57163.90523705474 1.031314089456978 0.9735673891947094 0.9303338862938846 1.0173440614566591 0.9558849682153066 1.0376512590379974 0.9184501794899805 1.0624165648509667 1.015263767364362 1.0 15.802816859203581 -7.786130149242089 24.999626307379998 1.029130095086265 0.9810929996519888 0.20665655294693774 0.04046809452336057 344.02750485022375 348325.74419101793 0.020756320288658436 0.009978134754624604 1.636326074228228e-08 7.786130149242089 -0.048037095434276145 ALELTGLK ddPTM_PC-9_Lapatinib_30min_R1 2 ALELTGLK 8 0 P19338 P19338 NCL Nucleolin 0 ; 130.27 0.016484 33336000.0 136456.0 144823.0 146183.0 148612.0 140432.0 142883.0 146929.0 125461.0 122112.0 128898.0 False True 134510.11241703437 144487.67124139823 134164.39802269838 159541.42223509884 132172.06585993496 136772.22716654107 154536.26469088177 131290.37607789872 108358.46066363376 151177.8475542113 0.889747503309306 0.9557463185179031 0.887460697405339 1.0553227527458242 0.874281966559545 0.9047107719766649 1.0222150082899293 0.8684498304609009 0.7167614992320696 1.0 17.20588722798324 -7.985463020414231 24.291896159722327 0.8364557140380574 0.9405943955786662 0.1466771767797328 0.08498300340396843 225.74242163636774 377224.6122574364 0.043539220355600365 0.02089997531885688 1.0340391442638119e-08 7.985463020414231 0.10413868154060879 ALENDFFNS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALENDFFNSPPR 12 0 F5H148;Q9NYV6-3;Q9NYV6;H3BMT1;Q9NYV6-2;A6NIE6 F5H148 RRN3;RRN3P2 RNA polymerase I-specific transcription initiation factor RRN3;Putative RRN3-like protein RRN3P2 1 ALENDFFNS(1)PPR;ALENDFFNS(1)PPR 194.59 1.5841e-05 5880900.0 11657.0 13297.7 15216.6 20056.9 25957.0 25710.0 32742.0 33279.0 31644.0 26391.0 True False 13630.299863755268 14617.807774562303 15579.421453276866 18933.176918347155 20870.912183883593 24361.722340131688 29640.44072844795 32405.46151201515 32106.733635433575 31175.479388958964 0.43721219788467935 0.4688879870036357 0.49973318000667016 0.6073098887150549 0.6694656375123837 0.7814385798590022 0.9507613454356484 1.039453511130026 1.029871368932483 1.0 14.928124124263777 -6.760876556706832 0.8085056637517917 1.0520538438553695 0.449225032298546 0.9843856044653599 0.02882756753169621 0.07206085134624396 0.10296454246915766 0.020395417587589202 0.019513370447672918 1.7342968819704794e-07 6.760876556706832 -0.6028288115568234 down ALENDFFNS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 2 ALENDFFNSPPR 12 0 F5H148;Q9NYV6-3;Q9NYV6;H3BMT1;Q9NYV6-2;A6NIE6 F5H148 RRN3;RRN3P2 RNA polymerase I-specific transcription initiation factor RRN3;Putative RRN3-like protein RRN3P2 1 ALENDFFNS(1)PPR;ALENDFFNS(1)PPR 110.25 0.0012151 5832100.0 13759.8 13174.2 18741.4 15561.4 21833.5 23884.0 23594.0 21538.0 27811.0 25962.0 True False 13563.582728761712 13143.695949320443 17200.554435896094 16705.83726730863 20549.296456312568 22862.536996323335 24815.58187367137 22538.734108334687 24678.632317186824 30449.4971078095 0.4454452131258026 0.431655600182291 0.5648879643232138 0.5486408267486302 0.6748648880326569 0.7508346333397964 0.8149750974805696 0.7402005369262434 0.8104775008207739 1.0 14.89413078088104 -5.3289208744333125 0.20574292211472608 1.0286362727660212 1.5071320720485188e-16 0.9447501664360691 0.04026717153820508 2.4423444465152877 0.11997131349973043 0.09794277425452066 0.6544505329029583 4.688988046075035e-06 5.3289208744333125 -1.028636272766021 down ALENDFFNS(ph)PPRK ddPTM_PC-9_AZD4547_30min_R2 1 ALENDFFNSPPRK 13 1 F5H148;Q9NYV6-3;Q9NYV6;H3BMT1;Q9NYV6-2;A6NIE6 F5H148 RRN3;RRN3P2 RNA polymerase I-specific transcription initiation factor RRN3;Putative RRN3-like protein RRN3P2 1 ALENDFFNS(1)PPRK 58.67100000000001 0.029555 12021000.0 9259.5 8281.9 12120.0 16992.0 16618.0 14231.0 14704.0 13750.0 10537.0 16785.0 True False 12203.828390435378 10958.862213618433 11959.280880932682 13074.756923783018 14310.877547560016 13341.133320321154 16012.6275145776 11625.25344356684 11093.96430828816 16197.362258956382 0.7534454187864591 0.6765831397984999 0.7383474352016643 0.8072151943476654 0.8835313626233662 0.8236608595294047 0.9885947636766207 0.7177250997852209 0.6849241333818855 1.0 13.983471268846678 -5.792107739256654 3.0325387570591267 0.8414874397444335 0.7138751507472111 0.25781951178081663 0.09586322524390155 0.3704151749050342 6.96944893833892 0.02846669843692679 0.04857419920092435 1.613958118354969e-06 5.792107739256654 -0.12761228899722243 ALENDFFNS(ph)PPRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALENDFFNSPPRK 13 1 F5H148;Q9NYV6-3;Q9NYV6;H3BMT1;Q9NYV6-2;A6NIE6 F5H148 RRN3;RRN3P2 RNA polymerase I-specific transcription initiation factor RRN3;Putative RRN3-like protein RRN3P2 1 ALENDFFNS(1)PPRK;ALENDFFNS(1)PPRK 62.104 0.023278 26398000.0 30817.0 34756.0 38494.0 42415.0 59518.0 75618.0 75020.0 74724.0 73746.0 48643.0 True False 36033.70943650561 38206.34598559806 39411.84294930797 40038.62506128537 47855.87515353792 71652.45896211898 67913.5625022346 72762.57417662255 74824.39573627488 57461.5908422239 0.6270920959262293 0.6649023360753057 0.6858815144454263 0.69678935919512 0.8328324094774711 1.2469626738817567 1.1818949233185934 1.266281930418731 1.3021636651467792 1.0 15.810310314438972 -6.629262738463208 2.9929594742523826 1.2181890883484 0.6732879160104751 0.9062679647774987 0.08109782688649247 0.06861482036737056 1.2356459037872098 0.02781040801489404 0.027815938656372056 2.348211775355696e-07 6.629262738463208 -0.5449011723379248 ALENDFFNS(ph)PPRK ddPTM_PC-9_Lapatinib_30min_R1 2 ALENDFFNSPPRK 13 1 F5H148;Q9NYV6-3;Q9NYV6;H3BMT1;Q9NYV6-2;A6NIE6 F5H148 RRN3;RRN3P2 RNA polymerase I-specific transcription initiation factor RRN3;Putative RRN3-like protein RRN3P2 1 ALENDFFNS(1)PPRK;ALENDFFNS(1)PPRK 82.94200000000001 0.004560600000000001 19383900.0 25623.0 22856.2 23198.0 27799.0 40248.0 46096.0 37986.0 43043.0 52234.0 44388.0 True False 25257.61132131729 22803.277873180745 21290.74998686958 29843.43119474551 37880.691770612524 44124.581535024285 39952.72921307453 45042.9349161969 46350.85687159526 52060.40665670782 0.48515970088110955 0.43801574627620804 0.4089624218124761 0.5732462174476749 0.7276295788544656 0.8475650569920965 0.7674302176801523 0.8652052069668814 0.8903283675296281 1.0 15.667898960583145 -6.3106093805415995 1.3557618809935539 0.8711628740670283 0.4345093561113889 0.9174578741347627 0.057184073509412535 0.11282025177757182 0.42007489190616515 0.022484890434824222 0.03028565364744325 4.890920678687054e-07 6.3106093805415995 -0.4366535179556394 ALENDPDCR ddPTM_PC-9_AZD4547_30min_R2 3 ALENDPDCR 9 0 A0A0A0MSQ0;P13797-3;P13797-2;P13797;U3KQI3;P13796;Q5TBN3 A0A0A0MSQ0;P13796 PLS3;LCP1 Plastin-3;Plastin-2 0 ;; 159.58 0.00059815 45187000.0 238732.0 238428.0 344596.0 462690.0 408830.0 336225.0 272680.0 379890.0 278651.0 319377.0 False True 314643.8100659236 315495.1882863375 340026.43188497314 356023.96898924 352071.0114194823 315200.79759855155 296947.9917488455 321186.729503754 293379.92298270896 308195.7084407935 1.0209221006280456 1.0236845603154991 1.1032808782614651 1.155187951157453 1.1423618232734656 1.0227293533488764 0.9635046290915217 1.0421518558083886 0.951927346642691 1.0 18.233487247210043 -6.949207821731262 7.033939380358669 0.9928724606752655 1.0896451460063572 0.5125335783600118 0.04622076361787199 0.19699154288458018 21.752526870839404 0.018153727299547038 0.01594241744928664 1.1240669486148362e-07 6.949207821731262 0.09677268533109173 ALENDPDCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ALENDPDCR 9 0 A0A0A0MSQ0;P13797-3;P13797-2;P13797;U3KQI3;P13796;Q5TBN3 A0A0A0MSQ0;P13796 PLS3;LCP1 Plastin-3;Plastin-2 0 ;; 159.58 1.3833e-15 9103400.0 202060.0 217853.0 223116.0 250889.0 266998.0 236542.0 242244.0 215309.0 212020.0 170874.0 False True 236264.76713308698 239480.00609968105 228435.93161214193 236832.50272311314 214681.65856118035 224137.32111160783 219296.89462531745 209657.3668887428 215120.3913975671 201852.10356216016 1.1704845427103983 1.1864132296542227 1.1316995343662362 1.1732971742361893 1.0635591840392653 1.1104036923875056 1.0864236277715342 1.038668228811294 1.065732720151321 1.0 17.62293909609736 -6.267449989001293 0.25858238270485623 0.9921350237720673 1.2519038566842642 0.8261943400059857 0.02476883940454717 1.630404103432487 0.18193014859058365 0.03913511340670602 0.1349263480545983 5.401943170328825e-07 6.267449989001293 0.2597688329121969 ALENDPDCR ddPTM_PC-9_Lapatinib_30min_R1 4 ALENDPDCR 9 0 A0A0A0MSQ0;P13797-3;P13797-2;P13797;U3KQI3;P13796;Q5TBN3 A0A0A0MSQ0;P13796 PLS3;LCP1 Plastin-3;Plastin-2 0 ;;; 146.79 0.0019268 57548500.0 250527.0 318670.0 378684.0 312893.0 347419.0 344339.0 319391.0 294992.0 347716.0 267216.0 False True 246954.4390389745 317932.1391940258 347550.0632825116 335904.1950004503 326984.49747203407 329612.42366341426 335927.50318783504 308698.405241242 308552.56246819336 313403.9295570613 0.7879749286743121 1.0144484775393987 1.1089524747622328 1.0717931822845648 1.0433324749123805 1.0517175841708835 1.0718675533603126 0.9849857520214579 0.9845204012096325 1.0 18.257663743324983 -4.7687954236839944 4.441751589129999 1.0431287053725216 0.7676411347301118 0.7917793516564682 0.038433405393453586 0.09085805572725815 3.886236520379392 0.010267108847186228 0.0797077976460875 1.702960506485844e-05 4.7687954236839944 -0.2754875706424098 ALEQSQSLPLPAPTST(ph)SPSR ddPTM_PC-9_Lapatinib_30min_R1 1 ALEQSQSLPLPAPTSTSPSR 20 0 H0Y7A3;H3BLT1;H7C2S1;H0Y4M6;H7BYP9;O15068-5;O15068-4;O15068-3;O15068-2;O15068-6;O15068-8;O15068-10;O15068-9;O15068 H0Y7A3 MCF2L Guanine nucleotide exchange factor DBS 1 ALEQSQSLPLPAPT(0.009)S(0.1)T(0.336)S(0.336)PS(0.218)R 137.86 9.007899999999999e-10 0.0 13133.0 10922.0 17224.0 15054.0 16851.0 16303.0 12291.0 11893.0 17089.0 7942.1 True False 12945.721011702763 10896.710780045676 15807.909206562706 16161.121378671847 15859.857310340683 15605.758694149188 12927.367839675127 12445.592197531081 15164.256864852236 9314.881402816955 1.3897891397509141 1.1698174468169131 1.6970596321046199 1.7349787592340673 1.7026365258439504 1.6753577441608416 1.3878188331808181 1.3360977622074024 1.6279602722871325 1.0 13.185321685535166 -10.57187991474447 0.5646572245083756 0.8450520815695655 1.5351614441361625 0.41887154254106174 0.18439480530683208 28.689937393763998 5.1629437261529665 7.5608283394393805 0.08708584638815854 2.6799092347555667e-11 10.57187991474447 0.690109362566597 ALEQSQSLPLPAPTSTSPS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 ALEQSQSLPLPAPTSTSPSR 20 0 H0Y7A3;H3BLT1;H7C2S1;H0Y4M6;H7BYP9;O15068-5;O15068-4;O15068-3;O15068-2;O15068-6;O15068-8;O15068-10;O15068-9;O15068 H0Y7A3 MCF2L Guanine nucleotide exchange factor DBS 1 ALEQSQSLPLPAPT(0.008)S(0.009)T(0.009)S(0.261)PS(0.713)R 82.03399999999999 0.0011450999999999998 4432400.0 13768.0 14186.0 16237.0 14057.0 17972.0 14699.0 11521.0 13001.0 16611.0 9896.7 True False 13571.665795258032 14153.153188585235 14902.056536632535 15090.798672777348 16914.922294311473 14070.358035042573 12117.50100731406 13605.073922483938 14740.094258415373 11607.331408476168 1.1692322134739277 1.2193287751093245 1.2838486308532915 1.3001092276694541 1.457261940669625 1.212195770060274 1.0439523591499547 1.172110405372671 1.2698951843187254 1.0 13.502748706077824 -7.000354263232848 24.999348975583025 1.1347237284023113 1.2881043358168194 0.3879364530638991 0.09679679412755164 14.893461953668409 1051083.164653954 0.03558444775154011 0.031043714390327857 9.991846113711736e-08 7.000354263232848 0.1533806074145081 ALES(ph)PERPFLAILGGAK ddPTM_PC-9_AZD4547_30min_R2 4 ALESPERPFLAILGGAK 17 1 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 1 ALES(1)PERPFLAILGGAK;ALES(1)PERPFLAILGGAK;ALES(1)PERPFLAILGGAK;ALES(1)PERPFLAILGGAK 89.46600000000001 0.0015452999999999999 82958200.0 24714.22 32630.579999999998 33713.6 59516.8 44676.7 31948.499999999996 28375.44 38868.2 29314.499999999996 32253.600000000002 True False 32572.8278722896 43177.77685922959 33266.53563592508 45796.12128539369 38474.1113809769 29950.755244486005 30900.799189488964 32862.012792381436 30864.004623262124 31124.4112812318 1.0465363530243286 1.3872640503650597 1.0688245742333122 1.47138915726284 1.236139409460156 0.9622914622820988 0.9928155398756835 1.055827610535317 0.9916333627769948 1.0 14.925758928387037 -6.741896173662414 10.808563182779196 1.0035151937476268 1.2533619432567444 0.4963177389765876 0.12136515887616695 0.3379145961350874 182.21751952270967 0.03830432654714904 0.03768781920128151 1.81177317960965e-07 6.741896173662414 0.24984674950911767 ALES(ph)PERPFLAILGGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALESPERPFLAILGGAK 17 1 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 1 ALES(1)PERPFLAILGGAK;ALES(1)PERPFLAILGGAK 105.53 0.0034578000000000005 24074600.0 19213.6 21222.5 20078.46 25260.89 35996.2 28422.0 20847.4 23921.0 26639.2 22662.8 True False 22466.082994102086 23329.329545383684 20557.206634383576 23845.60423021036 28943.003010883796 26931.500285928556 18872.583349894492 23293.09909639454 27028.747903584925 26771.386241373897 0.839182655374858 0.8714277749774989 0.767879797072794 0.8907123454577828 1.0811170833639452 1.0059807902030569 0.7049535343346478 0.8700744476352954 1.0096133110138796 1.0 14.708404224235125 -1.5228787452803376 0.07804684206580731 1.0667600654593814 0.47022958873326853 0.1374573197357959 0.104612707119423 530.3852876630893 3.0373635950816857 3.607400126089633 34.22240617236592 0.029999999999999995 1.5228787452803376 -0.5965304767261128 ALES(ph)PERPFLAILGGAK ddPTM_PC-9_Lapatinib_30min_R1 2 ALESPERPFLAILGGAK 17 1 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 1 ALES(1)PERPFLAILGGAK;ALES(1)PERPFLAILGGAK 60.937 0.015969999999999998 35596300.0 99446.8 79741.2 91576.5 96562.6 95237.0 89340.3 80167.7 83840.9 80241.3 72592.4 True False 98028.67039569037 79556.5641506849 84047.4336655126 103664.13572739046 89635.3469031462 85519.42363141112 84318.3912424312 87736.45429025334 71203.67981565135 85139.89961670707 1.1513834387520716 0.9344216343787356 0.9871685783503074 1.217574089164751 1.0528007116132068 1.0044576516581842 0.990351076546082 1.0304975068708766 0.8363138802864997 1.0 16.377547768675832 -7.5208861716601225 1.2275473554646714 0.9383523296308897 1.0606177106657737 0.24894951177497915 0.08715726468220499 0.7515825780465666 2.1256324684588934 0.06735174521087471 0.031149387586922803 3.013795834873392e-08 7.5208861716601225 0.12226538103488405 ALESISS(ph)DQQSEMVK ddPTM_PC-9_AZD4547_30min_R2 1 ALESISSDQQSEMVK 15 0 Q8TB72-4;A0A0A0MR59;Q8TB72-3;A0A0C4DG68 Q8TB72-4 PUM2 Pumilio homolog 2 1 ALES(0.045)IS(0.229)S(0.726)DQQSEMVK 56.568999999999996 0.045765 3862100.0 19050.0 13796.0 18240.0 30381.0 22521.0 20133.0 13527.0 13746.0 10143.0 14726.0 True False 25107.503735384616 18255.28720451587 17998.12568219573 23377.129831770955 19394.34789075694 18874.080327315427 14730.876794728712 11621.871551655982 10679.138272655095 14210.447222245557 1.7668341708542716 1.284638471894 1.2665418196002165 1.6450664406378102 1.3647950403979063 1.328183415492318 1.0366230256053064 0.81783995745487 0.7514990982083645 1.0 13.794664338434364 -7.3075934052830265 1.7882600578083179 0.8333172379594294 1.45535371435485 0.7540823820615897 0.15536746322358003 0.17853948767140518 1.1122669190119407 0.0849844693784751 0.05075775986963853 4.925004081162143e-08 7.3075934052830265 0.6220364763954207 ALESPERPFLAILGGAK ddPTM_PC-9_AZD4547_30min_R2 2 ALESPERPFLAILGGAK 17 1 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 ; 147.7 0.00010235 8631900.0 12594.5 11791.7 13697.5 14886.8 15626.8 13838.900000000001 11386.7 12691.5 12326.8 10566.8 False True 16599.289018126066 15603.136425738596 13515.862200212488 11454.878258767249 13457.28855820259 12973.55139530548 12400.094241039216 10730.320296656617 12978.369482339036 10196.859548283606 1.6278824808291248 1.5301903837995892 1.3254926319434845 1.1233731527365598 1.319748349428604 1.2723085312564948 1.2160699264634347 1.0523161808640196 1.272781038209321 1.0 13.315837275693717 -1.5228787452803945 0.37583792048492476 1.1313977785181484 8.497593317377925 0.7413256527437613 0.09458861300358282 34.409883921041775 0.47217612787669705 0.07441879505423887 183.93577778766914 0.029999999999996068 1.5228787452803945 7.366195538859777 ALESPERPFLAILGGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ALESPERPFLAILGGAK 17 1 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 ;; 141.82 0.00013301 15012500.0 21366.2 23236.0 16641.4 21679.8 24077.6 21183.0 22719.9 16737.5 20114.899999999998 18676.100000000002 False True 24983.07565831412 25542.71651862576 17038.194088860953 20465.15109285995 19359.767122497815 20072.126189459734 20567.70659416848 16298.158359847144 20409.042358847895 22061.929090073758 1.132406670165333 1.1577734845552603 0.7722894049426932 0.927622920430279 0.8775192343088567 0.9098082995149644 0.9322714487112749 0.7387458410053596 0.9250796825392055 1.0 14.42927132492131 -5.248416971586397 24.96480948881379 0.8798563661887498 1.1450901286355222 0.6650379049896488 0.07363137070688058 410.95031126804696 787815.4475747162 0.017797411949190045 0.04646700981409306 5.643948320284136e-06 5.248416971586397 0.2652337624467723 ALESPERPFLAILGGAK ddPTM_PC-9_Lapatinib_30min_R1 1 ALESPERPFLAILGGAK 17 1 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 98.654 0.0017300999999999998 5171200.0 10035.0 10309.0 9767.7 8820.7 9269.3 8339.5 9169.2 7821.3 9669.6 7824.0 False True 9891.899059806377 10285.130143883069 8964.637410412366 9469.403702992615 8724.097998144971 7982.839025323999 9643.936310759835 8184.706151059427 8580.507822597874 9176.367975175313 1.0779754132099737 1.1208279977118696 0.9769265394178025 1.0319337376846751 0.9507136180399629 0.8699344933550889 1.0509535294192023 0.8919330799725322 0.9350657957277421 1.0 13.163707529690226 -5.511718752484425 1.1421773404910862 0.9473426179578256 1.1120980573634054 0.48409297868794665 0.055260076437167925 0.5260964649739737 1.1790239346936975 0.018607288994299514 0.07712492487100535 3.0780895289371546e-06 5.511718752484425 0.1647554394055798 ALEVAGPDGQASAISPAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 ALEVAGPDGQASAISPASPR 20 0 Q0VDD7-2;Q0VDD7;K7EIN8 Q0VDD7-2 C19orf57 Uncharacterized protein C19orf57 1 ALEVAGPDGQASAISPAS(1)PR;ALEVAGPDGQASAIS(0.001)PAS(0.999)PR;ALEVAGPDGQASAISPAS(1)PR;ALEVAGPDGQASAIS(0.034)PAS(0.966)PR 215.43 3.2316999999999992e-37 44829700.0 85532.1 71219.0 113411.3 146390.2 135386.5 104825.8 87099.7 114943.2 96969.2 111012.6 True False 112729.52862180005 94239.14898654798 111907.3920603731 112642.20109604426 116590.42141609885 98271.02615482519 94851.40456552323 97181.36957197025 102094.7939454547 107126.08266360544 1.0523070182244076 0.8797031184503902 1.044632542121248 1.0514918336905905 1.0883476602258768 0.9173398644979237 0.8854183986487508 0.9071681438883253 0.9530339522079804 1.0 16.708950259362886 -6.790041614529541 24.998666434039333 0.9238416696688503 1.0180707900963502 0.36074068186965347 0.059605353105175105 240.43989774334506 210145.42817974478 0.021723369911612427 0.01916142678740863 1.6216547013463158e-07 6.790041614529541 0.09422912042749987 ALEVAGPDGQASAISPAS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ALEVAGPDGQASAISPASPR 20 0 Q0VDD7-2;Q0VDD7;K7EIN8 Q0VDD7-2 C19orf57 Uncharacterized protein C19orf57 1 ALEVAGPDGQAS(0.003)AIS(0.001)PAS(0.995)PR;ALEVAGPDGQASAIS(0.001)PAS(0.999)PR;ALEVAGPDGQASAISPAS(1)PR;ALEVAGPDGQASAISPAS(1)PR 229.23 3.8268999999999996e-36 32077900.0 88408.0 78021.0 106421.0 109786.0 115462.0 100979.0 103888.0 104918.0 86946.0 79203.0 True False 103373.72826240656 85766.40925717405 108958.48024389024 103635.04635101455 92838.04995090197 95683.48347663002 94046.97655601351 102164.01366980984 88217.42076432816 93561.8769293972 1.104870184898209 0.9166811533921482 1.1645606503395767 1.107663182400869 0.9922636547892104 1.0226759724886003 1.0051848000760222 1.0919406175113813 0.9428778436210506 1.0 16.513633183197598 -6.272840702255114 24.476679506251926 1.0142315031102838 1.0687548098478972 0.1704522269790354 0.0686233674922233 1223.9374928141135 2627578.1847823896 0.02120895062257782 0.024239731769117437 5.335305568024923e-07 6.272840702255114 0.05452330673761341 ALEVAGPDGQASAISPAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 ALEVAGPDGQASAISPASPR 20 0 Q0VDD7-2;Q0VDD7;K7EIN8 Q0VDD7-2 C19orf57 Uncharacterized protein C19orf57 1 ALEVAGPDGQASAISPAS(1)PR;ALEVAGPDGQASAISPAS(1)PR;ALEVAGPDGQASAISPAS(1)PR 259.32 1.8665999999999996e-66 30464000.0 152090.0 112612.1 144154.1 128759.5 132540.7 116299.7 107753.6 110106.1 147614.0 105911.1 True False 149921.1687101097 112351.3536013169 132302.30634891803 138228.90315910027 124744.91661104218 111325.83293884214 113332.55416558599 115222.03136807999 130988.15687566843 124217.69251733026 1.2069228277541333 0.9044714269317327 1.065084237742219 1.1127956119440492 1.0042443558806116 0.896215592825559 0.9123704672728031 0.9275814824205075 1.0545048311648004 1.0 16.922511147907855 -6.521737334362197 12.961570855274386 0.9506812565635022 1.0596570567920434 0.295898224636009 0.08173276860096619 0.15837968024192003 1460.3795185109275 0.026017548292853684 0.02687672966550764 3.007894957497724e-07 6.521737334362197 0.10897580022854114 ALEYVFKFIVRS(ph)RTLFS(ph)QLY(ph)EGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALEYVFKFIVRSRTLFSQLYEGK 23 3 E5RFJ0;Q92608 E5RFJ0 DOCK2 Dedicator of cytokinesis protein 2 3 ALEY(0.006)VFKFIVRS(0.505)RT(0.505)LFS(0.992)QLY(0.991)EGK 41.115 0.045609 27915000.0 32610.0 25170.0 26060.0 33120.0 36354.0 30638.0 38629.0 32666.0 28458.0 27794.0 True False 38130.2289231414 27668.711257265026 26681.369233100348 31264.39377648877 29230.69466937257 29031.289344883488 34969.781470258866 31808.55211248793 28874.144412753376 32832.83218281705 1.1613444953766956 0.8427147284523736 0.8126429387673705 0.9522295732029746 0.8902885534398203 0.8842152021255392 1.065085743305452 0.9688031765086298 0.8794289890064543 1.0 15.00285158270038 ALGIDGLLALR ddPTM_PC-9_Lapatinib_30min_R1 1 ALGIDGLLALR 11 0 Q13395 Q13395 TARBP1 Probable methyltransferase TARBP1 0 106.6 0.011122 1630700.0 11034.0 13149.0 10393.0 9513.5 10509.0 11825.0 9166.7 7276.1 10454.0 10535.0 False True 10876.653136612218 13118.554298372144 9538.52765814017 10213.15452610566 9890.88128148894 11319.272315421342 9641.306872992433 7614.174168708972 9276.560434499697 12355.960712994885 0.8802757947565449 1.0617186800031853 0.7719778234733627 0.8265771285080556 0.8004947175889451 0.9160981147760329 0.7802960123410376 0.6162348963040218 0.7507761355006128 1.0 13.592919568442662 -5.27540304357299 24.606215435458257 0.7973951846600895 0.9709972404595126 0.27803439539956043 0.10411141737951672 676.2982208744041 1191746.5016364313 0.027481472895904004 0.05768999264647251 5.303919896489416e-06 5.27540304357299 0.17360205579942312 ALGQNPTNAEVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALGQNPTNAEVLK 13 0 F8W1R7;G3V1V0;P60660-2;P60660;J3KND3;G8JLA2;B7Z6Z4;F8VPF3;F8W1I5;P14649 F8W1R7 MYL6;MYL6B Myosin light polypeptide 6;Myosin light chain 6B 0 ; 187.85 0.00014685 8152800.0 26169.0 26055.0 26960.0 25706.0 33327.0 30248.0 28080.0 31583.0 25461.0 21689.3 False True 30598.894838690187 28641.56820850379 27602.82864636936 24265.77615997647 26796.813589871268 28661.741631439276 25420.059118405035 30753.97971495461 25833.318957520336 25621.398397595673 1.1942710684191853 1.117876852935222 1.0773349767263143 0.9470902322901152 1.0458763090927112 1.1186642191289962 0.9921417529181572 1.2003240118947052 1.00827123315582 1.0 14.645061598641174 -4.968439480536072 2.1851720554846468 1.052478163901791 1.203240589901551 0.31627864255393956 0.06798628707727158 0.5536446999479236 4.1033257527420215 0.01818856638635082 0.14144889171948108 1.075376444966672e-05 4.968439480536072 0.15076242599975997 ALGQNPTNAEVLK ddPTM_PC-9_Lapatinib_30min_R1 2 ALGQNPTNAEVLK 13 0 F8W1R7;G3V1V0;P60660-2;P60660;J3KND3;G8JLA2;B7Z6Z4;F8VPF3;F8W1I5;P14649 F8W1R7 MYL6;MYL6B Myosin light polypeptide 6;Myosin light chain 6B 0 ; 194.39 5.9736e-06 23082000.0 73567.0 79199.0 74975.0 66302.0 63202.0 68370.0 70068.0 57110.0 68784.0 61474.0 False True 72517.92108946432 79015.61958147207 68810.8449118693 71178.07025698827 59484.58261991287 65445.97447825435 73695.778194643 59763.53909030516 61036.82159236915 72099.6989910438 1.005800608106179 1.0959216291775 0.9543846350928172 0.9872173012238232 0.8250323295705024 0.9077149474144688 1.0221371132741826 0.8289013675040303 0.8465613927174804 1.0 16.137705615922137 -5.672774874238936 1.7891057405950577 0.9045913416512827 1.0480484789388014 0.3626764930127373 0.06969476828036686 0.3718083777365768 2.3964133729774826 0.02148340902564298 0.049437335024420055 2.124345376141929e-06 5.672774874238936 0.14345713728751863 ALGS(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 1 ALGSPTK 7 0 Q9NR45;Q5TBR1;Q5TBR0 Q9NR45 NANS Sialic acid synthase 1 ALGS(0.993)PT(0.007)K 70.919 0.042749 38996000.0 26143.0 23717.0 30314.0 34788.0 29209.0 30715.0 26462.0 30227.0 29219.0 27138.0 True False 34455.93019181943 31383.056438786807 29912.016553184276 26768.16406924223 25153.83453404022 28794.386194481343 28817.066736313416 25556.111697359625 30763.456688229242 26187.90688016431 1.3157191351523259 1.1983797171112403 1.1422072290871303 1.0221574481585403 0.9605133640173688 1.0995298832489464 1.1003959525356541 0.9758745444721575 1.1747199510446793 1.0 14.676613133614332 -5.134388588337202 1.5268031914572817 1.048515484931139 1.3288550603162004 0.6455248522401813 0.06370554475913269 0.3752381824144935 1.28470139019256 0.018486141033507843 0.12972730548861644 7.338569501436616e-06 5.134388588337202 0.28033957538506127 ALGS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ALGSPTK 7 0 Q9NR45;Q5TBR1;Q5TBR0 Q9NR45 NANS Sialic acid synthase 1 ALGS(0.891)PT(0.109)K;ALGS(0.881)PT(0.119)K;ALGS(0.852)PT(0.148)K 87.639 0.017806 215485000.0 251224.0 258443.0 236861.0 273673.0 307819.0 244454.0 251011.0 243190.0 221552.0 228848.0 True False 293751.26129982487 284099.5130497162 242508.6645403449 258339.98906983767 247504.07664718 231634.40190332764 227233.42091773378 236806.52018110355 224791.77886479563 270336.3308402291 1.0866140721331095 1.0509113302185833 0.8970627950250217 0.9556243819204553 0.9155413032274113 0.8568378552131248 0.8405582047054951 0.8759700164794278 0.8315263367159087 1.0 18.044395884943746 -4.837675425062994 0.7885556098679805 0.8757335845262451 1.2213534171537255 0.6398009299545315 0.050910037208790684 1.422350334240436 0.7143848277938926 0.019261200296565 0.4278004191372095 1.4531972754147835e-05 4.837675425062994 0.3456198326274804 ALGS(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 1 ALGSPTK 7 0 Q9NR45;Q5TBR1;Q5TBR0 Q9NR45 NANS Sialic acid synthase 1 ALGS(0.77)PT(0.23)K 73.233 0.036802999999999995 106900000.0 509840.0 572470.0 596890.0 582000.0 571080.0 455290.0 586720.0 439270.0 645110.0 482270.0 True False 502569.58810679364 571144.480887452 547816.0082620311 624802.2214950859 537490.1971864791 435818.3080328276 617097.4907569912 459680.08783397585 572450.9184905395 565629.7269156185 0.888513393465559 1.0097497597976426 0.968506395958491 1.1046134808050758 0.9502509709265381 0.7705010668540122 1.090991971235364 0.8126872863288382 1.0120594644346523 1.0 19.109498418040197 -6.510961223659797 24.974331042818694 0.9268417115782839 0.9967043578702207 0.05932350920646112 0.10067179817000906 1390.9053671113954 2914785.4812380434 0.030533626499861268 0.032805395327704746 3.0834632475125717e-07 6.510961223659797 0.06986264629193684 ALGVISNFQS(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 1 ALGVISNFQSSPK 13 0 Q6N039;E9PC87;O94876-2;O94876 Q6N039 DKFZp686H13261;TMCC1 Transmembrane and coiled-coil domains protein 1 1 ALGVIS(0.001)NFQS(0.5)S(0.5)PK 88.37 0.0066366 5063000.0 79593.0 106170.0 38409.0 31201.0 38229.0 41523.0 46239.0 42206.0 51326.0 16170.0 True False 78457.9892244314 105924.1698880651 35251.160283027595 33495.62562348482 35980.44538110578 39747.15808484064 48633.02917083538 44167.04484057818 45545.125393259164 18964.962954829345 4.1369967034105075 5.585255828885865 1.8587518661116627 1.7661846059633513 1.8972062042411488 2.095820496961171 2.5643619387324557 2.3288758826355225 2.4015404354724192 1.0 14.211048933099017 -5.268110328962967 24.996941250158812 2.049666830806362 4.861126323192175 0.82675549855155 0.5252997099610114 170.1013630416993 637394.498908108 0.13199612693556784 0.2852447944252756 5.393735816595238e-06 5.268110328962967 2.8114594923858127 ALGVISNFQSS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 ALGVISNFQSSPK 13 0 Q6N039;E9PC87;O94876-2;O94876 Q6N039 DKFZp686H13261;TMCC1 Transmembrane and coiled-coil domains protein 1 1 ALGVISNFQS(0.212)S(0.788)PK 109.16 0.00081774 6320000.0 48177.0 54284.0 55440.0 40656.0 46392.0 38810.0 53901.0 52147.0 57899.0 39248.0 True False 63496.283856148286 71830.24141852261 54704.8293761475 31283.38732893847 39951.27158421011 36383.20456479965 58698.084579926996 44088.879368849455 60959.42293684877 37873.93946616143 1.6765164847158085 1.8965611296574925 1.4443923750003265 0.8259871502643313 1.0548485884312266 0.9606395605428456 1.5498278079144885 1.164095417331508 1.6095347829161826 1.0 15.208917870819366 -5.499638150712641 5.685433022510931 1.17220679711007 1.7662952507454242 0.51920238089301 0.23837292668929147 0.14114563207259817 14.612133875944204 0.06560124373964214 0.13075068970143938 3.1649135323552883e-06 5.499638150712641 0.5940884536353541 ALGVISNFQSS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALGVISNFQSSPK 13 0 Q6N039;E9PC87;O94876-2;O94876 Q6N039 DKFZp686H13261;TMCC1 Transmembrane and coiled-coil domains protein 1 1 ALGVISNFQS(0.047)S(0.953)PK;ALGVISNFQS(0.213)S(0.787)PK 215.34 2.1077e-14 10484900.0 106939.0 136069.0 83546.0 90156.0 121993.0 61460.0 88292.0 46413.0 57561.0 63954.0 True False 125041.6605584731 149577.0310713068 85538.05348996959 85104.8516096958 98089.34738407779 58236.92940585355 79928.34258127553 45194.70792863845 58402.7207302867 75548.35394041457 1.6551209131186921 1.979884713163692 1.1322292151783209 1.1264951143319217 1.2983651167494852 0.7708563637506299 1.0579759639014172 0.5982222718483553 0.7730508698620921 1.0 16.205112701612332 -5.3773890246082265 0.6199402575680606 0.8069586222474651 2.137412077367287 0.7139056975703664 0.21306956679760672 0.9781391952208852 0.46570349310326153 0.11526502946414402 0.8409142100485045 4.193831480882351e-06 5.3773890246082265 1.3304534551198222 ALGVSNFSHFQIEK ddPTM_PC-9_AZD4547_30min_R2 1 ALGVSNFSHFQIEK 14 0 O60218 O60218 AKR1B10 Aldo-keto reductase family 1 member B10 0 97.45 0.0046486 0.0 11196.0 11417.0 22103.0 34565.0 27363.0 21723.0 13922.0 23555.0 16756.0 20447.0 False True 14756.095108733138 15107.321978396472 21809.899778156363 26596.573273926584 23564.119769760764 20364.65737596348 15161.03102951233 19915.11599005214 17641.687951948024 19731.156753582432 0.7478575783983871 0.7656582007364344 1.1053533277615115 1.3479479995057893 1.194259417430375 1.0321066134283297 0.7683802434319853 1.0093232869601683 0.8941030762803585 1.0 14.268187917148548 -10.68041663447477 14.795747512540144 0.999996591103513 0.9946470094427826 0.0 0.1879329233175122 0.0 0.0 0.20345752926394783 0.049345699028379604 2.0872927542794526e-11 10.68041663447477 -0.005349581660730407 ALGVSNFSHFQIEK ddPTM_PC-9_Lapatinib_30min_R1 3 ALGVSNFSHFQIEK 14 0 O60218 O60218 AKR1B10 Aldo-keto reductase family 1 member B10 0 ;; 132.24 1.163e-05 7804700.0 71754.1 53254.3 70445.8 69817.5 74307.7 86067.8 74191.1 67509.5 75777.4 67075.4 False True 70730.87337590968 53130.99294028444 64654.01825265187 74952.11185435233 69937.06718055918 82386.88082784115 78032.35213815978 70646.23782554638 67242.55124060228 78669.29351764763 0.8990912491166945 0.6753714259346404 0.8218456701679702 0.9527492685254453 0.8890008293371852 1.0472558878307399 0.9919035579066823 0.8980154094011095 0.8547496517878093 1.0 16.263513007221555 -5.680343198003695 4.219587776630208 0.9472906967019438 0.7791360003894028 0.4616877907122119 0.07394077280284134 0.18017968760165748 6.001743663255749 0.020586725137318684 0.036491113927237015 2.087645732225814e-06 5.680343198003695 -0.16815469631254099 ALHSFIT(ph)PPTTPQLR ddPTM_PC-9_AZD4547_30min_R2 2 ALHSFITPPTTPQLR 15 0 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;J3QR75 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 ALHS(0.003)FIT(0.997)PPTTPQLR;ALHSFIT(1)PPTTPQLR 116.04 0.00031569 24909000.0 42569.0 44435.0 56522.0 80822.0 69691.0 65835.0 63917.0 58361.0 58818.0 58962.0 True False 56105.05650979465 58797.744776215004 55772.481349181304 62189.736587452375 60015.60760422461 61718.327042607154 69605.48917636408 49342.648452363974 61926.99940067311 56897.75832663604 0.9860679604934403 1.0333929930713897 0.9802228240523151 1.093008554580242 1.054797400974741 1.0847233504050795 1.223343260322772 0.8672160363348581 1.0883908474067718 1.0 15.796084193509204 -5.756002885222153 24.993207371145843 1.0610216003731099 1.0032444310687405 0.09136659788915613 0.0846990415674931 356.0881126209595 1637021.5478325987 0.023122864721805053 0.03862390387307184 1.7538688500288107e-06 5.756002885222153 -0.05777716930436938 ALHSFIT(ph)PPTTPQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALHSFITPPTTPQLR 15 0 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;J3QR75 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 ALHS(0.004)FIT(0.996)PPTTPQLR;ALHS(0.003)FIT(0.995)PPT(0.001)TPQLR 99.39200000000001 0.004342800000000001 20893000.0 32945.0 38291.0 40857.0 44853.0 57653.0 42475.0 40341.0 42737.0 40463.0 39772.0 True False 38521.937806589805 42092.27742359694 41831.18583103534 42340.03182538799 46356.30851552338 40247.53622703593 36519.60843645219 41615.19903359451 41054.69482652471 46982.348765021234 0.8199236270467117 0.8959168396224373 0.8903596122929262 0.9011901903233606 0.9866749903750247 0.8566522808029677 0.7773048686667907 0.8857624220051209 0.8738323201306251 1.0 15.519831218632762 -12.044131627387282 1.9718022805981348 2.29930235989373 0.8781385956808908 0.33802777357192537 0.05183791791516275 2211735.8360470184 145864.71104735602 12832185.381468993 0.014010489479344945 9.033756341942874e-13 12.044131627387282 -1.4211637642128392 ALHSFIT(ph)PPTTPQLR ddPTM_PC-9_Lapatinib_30min_R1 2 ALHSFITPPTTPQLR 15 0 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;J3QR75 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 ALHSFIT(0.998)PPT(0.001)TPQLR;ALHS(0.005)FIT(0.995)PPTTPQLR 95.87299999999999 0.0057754 18448100.0 59924.0 50986.0 65232.0 56831.0 61496.0 57109.0 54193.0 45027.0 49004.0 38642.0 True False 59069.47277128426 50867.94504957049 59868.876762801796 61010.5413226584 57878.926185787815 54666.58119758122 56998.84837161446 47119.11879914503 43484.653485003124 45321.21821277156 1.3033513903789644 1.1223869758036613 1.3209900157964134 1.3461805248973995 1.2770823130583344 1.20620281963595 1.2576636423147192 1.0396701734258949 0.9594767131115887 1.0 15.467899020185008 -7.820871177180964 3.4738816480208388 0.9835073159896089 1.2622760628142498 0.8012616618773338 0.060271578659565096 0.10562242488593893 2.5441232095768647 0.03801959396206801 0.01720075058928868 1.5105281488891167e-08 7.820871177180964 0.2787687468246408 ALHVNNDR ddPTM_PC-9_AZD4547_30min_R2 1 ALHVNNDR 8 0 Q6P2Q9 Q6P2Q9 PRPF8 Pre-mRNA-processing-splicing factor 8 0 69.423 0.034332 1829700.0 10497.0 7497.7 9851.4 12448.0 13410.0 10054.0 9396.3 9764.9 9173.6 11102.0 False True 13834.827648836344 9921.184899485252 9720.763999209588 9578.30591968286 11548.252973449253 9425.321790633743 10232.552496954944 8255.959080078974 9658.497767724417 10713.322359185808 1.291366691395606 0.9260605222971413 0.9073528895426934 0.8940556065196934 1.0779338646099415 0.8797758038665094 0.9551241112595998 0.7706254701652057 0.901540852025519 1.0 13.387118330023348 -4.7614667884686295 7.239737125847174 0.9190037585925818 1.2983426653999066 0.6780003094274879 0.07598811570526137 0.0615521796386479 20.63703347977039 0.019081911799447952 0.11465224297737159 1.7319414713672513e-05 4.7614667884686295 0.37933890680732485 ALHVNNDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALHVNNDR 8 0 Q6P2Q9 Q6P2Q9 PRPF8 Pre-mRNA-processing-splicing factor 8 0 79.71300000000001 0.017058 932510.0 5566.7 7252.7 8542.1 8315.6 10115.0 8034.8 8329.0 8899.6 6030.6 5361.7 False True 6509.032362663326 7972.7001245755255 8745.776060094653 7849.703891538948 8133.0383611350535 7613.44094354299 7540.016823261955 8665.99492990565 6118.78611622569 6333.733766806153 1.0276769757478408 1.2587678008126695 1.3808247049993698 1.2393485707715872 1.284082763907555 1.2020462532611538 1.1904537040659482 1.3682284808563343 0.9660630429862777 1.0 12.628840510825018 -8.276011171989643 24.899042744580548 0.9830314385493266 1.2469937181613633 0.5527115552275328 0.09384776509728052 632.654809762061 1081015.412289487 0.08808444824620534 0.023140962660288963 5.296498187625219e-09 8.276011171989643 0.26396227961203667 ALHVNNDR ddPTM_PC-9_Lapatinib_30min_R1 2 ALHVNNDR 8 0 Q6P2Q9 Q6P2Q9 PRPF8 Pre-mRNA-processing-splicing factor 8 0 ; 81.548 0.014879 2521700.0 17432.0 19284.0 17779.5 15029.3 22292.0 16928.1 18437.3 20768.6 21381.0 13093.2 False True 17183.416483362722 19239.34908280543 16317.738140854715 16134.604858275059 20980.82838775826 16204.124624328459 19391.893179598243 21733.584975501883 18972.84662808857 15356.342174407642 1.1189784838214936 1.2528601449679257 1.06260579215598 1.0506802124508818 1.3662647100117498 1.0552073169699032 1.2627937668591491 1.4152839737917755 1.235505591931135 1.0 13.90654699174856 -6.243050778872271 24.99588365853659 1.236922570000547 1.12648856729427 0.1239641890431783 0.128148489320601 1666.0669019065558 2264708.2456380255 0.03769615721938774 0.04857587613880355 5.714118217675096e-07 6.243050778872271 -0.11043400270627712 ALIAAQYSGAQVR ddPTM_PC-9_Lapatinib_30min_R1 1 ALIAAQYSGAQVR 13 0 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 0 159.94 0.0012778 4301700.0 17645.0 18235.0 13028.0 11165.0 16921.0 15358.0 16645.0 13588.0 16292.0 13501.0 False True 17393.379064303303 18192.77797785506 11956.888129534318 11986.111345348167 15925.740047965977 14701.174141246598 17506.79665538949 14219.348085432788 14457.0233976343 15834.629861048297 1.0984392573071369 1.1489234757932414 0.7551100489533475 0.756955574618948 1.0057538564347375 0.9284191844237614 1.1056018870674438 0.8979905567866193 0.91300040004075 1.0 13.950795523905057 -5.231711919571883 24.91613359889429 0.9208291152564848 1.1236814494330285 0.389093458353303 0.101908493735943 736.2250704753328 617066.2856448777 0.027734895509160737 0.07335742763697167 5.8652709634723905e-06 5.231711919571883 0.2028523341765437 ALIAQLPS(ph)PAIDHEQLR ddPTM_PC-9_AZD4547_30min_R2 2 ALIAQLPSPAIDHEQLR 17 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 ALIAQLPS(1)PAIDHEQLR;ALIAQLPS(1)PAIDHEQLR 90.765 0.0013206 4611200.0 19622.4 20994.5 25988.1 37471.0 30685.8 33840.5 26745.7 32981.0 23706.1 30445.0 True False 25861.915028725 27780.56155517601 25643.48081367711 28832.639871179006 26425.606345463773 31724.448185392983 29126.015486713663 27884.544277983845 24959.156049037665 29379.129816736782 0.880281859607425 0.9455883046389585 0.8728468465076342 0.9813987021070157 0.8994686537791723 1.07982940213975 0.9913845531980691 0.9491276444171094 0.8495539590426829 1.0 14.842504044753705 -5.770374311959216 24.99824780689698 0.9655041288214914 0.9041739311233321 0.19330472865998838 0.06043455620794802 335.318011777018 938157.2751509547 0.017425190678652207 0.02627496946300569 1.6967805920835356e-06 5.770374311959216 -0.06133019769815928 ALIAQLPS(ph)PAIDHEQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALIAQLPSPAIDHEQLR 17 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 ALIAQLPS(1)PAIDHEQLR;ALIAQLPS(1)PAIDHEQLR 116.39 7.957e-05 5693300.0 42851.0 44709.0 47993.9 45909.0 52111.0 50354.0 53168.0 50043.1 44797.5 36983.2 True False 50104.82795417148 49147.41404851261 49138.25659387931 43336.86756898617 41900.22363194352 47713.34759684911 48131.542137014236 48729.52165004729 45452.57868895638 43687.96140114991 1.1468795143380774 1.1249646921547365 1.1247550816730476 0.991963602308198 0.9590793959738452 1.0921394834320022 1.1017117895491313 1.1153993019405268 1.040391385434616 1.0 15.414948166836052 -5.643740029688368 8.277038767592332 1.0488650025787598 1.1330442752472998 0.4170059087796013 0.04808218836192833 0.2853486136235694 19.373313402161855 0.014633030633247711 0.02539563890357027 2.2712240082858323e-06 5.643740029688368 0.08417927266853997 ALIEMEK ddPTM_PC-9_Lapatinib_30min_R1 1 ALIEMEK 7 0 Q15233;Q15233-2;H7C367;C9JYS8 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 113.7 0.041395999999999995 3652700.0 37972.0 30000.0 34346.0 31740.0 34697.0 24809.0 34337.0 30997.0 31332.0 25717.0 False True 37430.51231678802 29930.53684319449 31522.204459394023 34074.265481536095 32656.190676926606 23747.976902603645 36114.80184776864 32437.233780111874 27803.060219413095 30162.149184251488 1.240976300731632 0.9923210929154237 1.0450914577351358 1.1297028362729282 1.0826877911597006 0.7873436590189381 1.1973550567353206 1.0754284643963061 0.9217864433191604 1.0 14.880451610112019 -4.754819350347825 24.946648603115044 1.031648736644115 1.2409766644967397 0.26278990792319135 0.10773976076808287 320.9850747336969 1209473.9557462228 0.02653446573011918 0.24952876436941307 1.7586549940702278e-05 4.754819350347825 0.20932792785262477 ALINS(ph)MDQNMFR ddPTM_PC-9_AZD4547_30min_R2 2 ALINSMDQNMFR 12 0 A0A087X0I9;Q04759-3;Q04759-2;Q04759 A0A087X0I9 PRKCQ Protein kinase C;Protein kinase C theta type 1 ALINS(1)MDQNMFR;ALINS(1)MDQNMFR 70.55199999999999 0.017634999999999998 12813700.0 68925.0 77338.0 79258.0 117544.0 88072.0 72443.0 66147.0 90986.0 62280.0 73727.0 True False 90841.71627093868 102335.99607298122 78206.98713374273 90446.04683669689 75844.72303337984 67913.12775799472 72033.95485628172 76926.20435028164 65571.99365286004 71145.8401707521 1.2768380562084292 1.4383974639609545 1.099248908243176 1.271276670844335 1.0660457849868703 0.9545621725037082 1.01248301634218 1.0812466922262285 0.9216560447594031 1.0 16.11849178576754 -5.940201160080618 0.9073231069370898 0.9916362776605614 1.3570305152127111 0.7072847592231088 0.08481625007301177 0.35745274308081526 0.583206637911709 0.03665212887350748 0.09024936841397793 1.1476219334295722e-06 5.940201160080618 0.3653942375521497 ALINS(ph)MDQNMFR ddPTM_PC-9_Lapatinib_30min_R1 1 ALINSMDQNMFR 12 0 A0A087X0I9;Q04759-3;Q04759-2;Q04759 A0A087X0I9 PRKCQ Protein kinase C;Protein kinase C theta type 1 ALINS(1)MDQNMFR 57.52 0.04308 4792600.0 36192.0 33316.0 30941.0 20049.0 38007.0 38163.0 38109.0 33452.0 34890.0 31787.0 True False 35675.89544320004 33238.858848928954 28397.150415713946 21523.470341503376 35771.502984637 36530.857452298085 40082.09755123092 35006.30204253 30960.320792012095 37281.3405964849 0.9569370326388899 0.8915682300347028 0.7616987469166115 0.5773255466980909 0.959501520393549 0.9798697382610331 1.0751248992105744 0.9389764821340838 0.830450844756672 1.0 15.186166118219932 -6.471933342115952 24.997344949653083 0.9681524762542068 0.7970425937382735 0.36521411021642725 0.10790446330401772 416.4245175795707 204326.57523955574 0.03592059906340765 0.04072969838626733 3.3733908132633837e-07 6.471933342115952 -0.1711098825159333 ALIQTCLNSPDS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 3 ALIQTCLNSPDSPPR 15 0 P11831 P11831 SRF Serum response factor 1 ALIQTCLNS(0.167)PDS(0.833)PPR;ALIQTCLNS(0.079)PDS(0.921)PPR;ALIQTCLNS(0.034)PDS(0.966)PPR 101.3 0.0017 10744000.0 19489.5 23028.2 52832.0 35382.7 39163.0 43432.0 29030.300000000003 30619.5 47357.0 27502.4 True False 19211.57615606342 22974.879617748393 48488.35689741762 37984.86179122707 36859.50933742045 41574.514604936965 30533.346887651165 32042.193751980365 42023.155968682004 32256.153195355535 0.5955941503536025 0.7122634704331847 1.503228131505753 1.1776004894686696 1.142712496254133 1.2888863204842154 0.9465898398587581 0.9933668642358142 1.3027950268642943 1.0 14.977286775361737 -5.10646164062866 6.787014042378188 1.1640590183559318 0.6241111098908668 0.6277257566152712 0.15975476917096143 0.14171348923489036 7.673788077374041 0.04114155959372731 0.11185873428538005 7.825973254836136e-06 5.10646164062866 -0.539947908465065 ALIQTCLNSPDS(ph)PPRSDPTTDQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ALIQTCLNSPDSPPRSDPTTDQR 23 1 P11831 P11831 SRF Serum response factor 1 ALIQT(0.004)CLNS(0.052)PDS(0.439)PPRS(0.306)DPT(0.099)T(0.099)DQR;ALIQT(0.001)CLNS(0.021)PDS(0.915)PPRS(0.061)DPT(0.001)T(0.001)DQR;ALIQT(0.007)CLNS(0.033)PDS(0.455)PPRS(0.455)DPT(0.025)T(0.025)DQR;ALIQTCLNS(0.002)PDS(0.814)PPRS(0.177)DPT(0.004)T(0.004)DQR 80.362 8.726e-05 33172400.0 46270.9 55023.3 60350.8 66128.5 76003.8 67706.2 68701.7 61652.8 62733.2 56153.0 True False 54103.64947806754 60485.64958767862 61789.79195368358 62423.534536489686 61111.40098784342 64155.56768204686 62193.77761876523 60034.47932654125 63650.554370445585 66333.09439309653 0.815635844717931 0.9118472482111966 0.9315077567090586 0.9410616994069596 0.9212807203850791 0.9671728459078747 0.9375980148038731 0.9050456619854178 0.9595595524798837 1.0 16.01744120772304 -3.816909667316549 1.1354240344711395 0.94339668720505 1.6971393354538236e-08 0.7159417083575523 0.024676478320085984 6.378424034799089 1.2966006297691655 0.007111868903461322 12.004217567997875 0.00015243697877442462 3.816909667316549 -0.9433966702336566 ALIQTCLNSPDS(ph)PPRSDPTTDQR ddPTM_PC-9_Lapatinib_30min_R1 2 ALIQTCLNSPDSPPRSDPTTDQR 23 1 P11831 P11831 SRF Serum response factor 1 ALIQTCLNS(0.008)PDS(0.964)PPRS(0.014)DPT(0.007)T(0.008)DQR;ALIQT(0.001)CLNS(0.013)PDS(0.74)PPRS(0.206)DPT(0.02)T(0.02)DQR 86.084 1.4979e-05 55223000.0 74832.0 72542.0 82067.0 52614.0 72100.0 60967.0 51383.0 41245.0 75976.0 38771.0 True False 73764.88195749183 72374.03345596735 75319.7680477813 56483.40907515882 67859.21975405386 58359.58353101847 54043.36032105006 43161.393272275214 67418.78281725162 45472.515690889864 1.6221860795854355 1.591599504807407 1.6563800551477108 1.2421439240159506 1.4923128558653516 1.283403450289214 1.1884840655929954 0.9491754000520876 1.4826270724836663 1.0 15.472707200530403 -6.0940248958607794 0.4449708751904097 1.0911377164509302 1.762976203001422 0.5687105725362722 0.15944742260885078 1.2633157673459474 0.42836927044737544 0.13718162831604497 0.4002178375064632 8.053322743337369e-07 6.0940248958607794 0.6718384865504918 ALIVLAHSER ddPTM_PC-9_AZD4547_30min_R2 2 ALIVLAHSER 10 0 B4DLR8;P15559-3;P15559-2;P15559;H3BRK3 B4DLR8 NQO1 NAD(P)H dehydrogenase [quinone] 1 0 ; 176.33 0.00010164 17674500.0 63108.0 78177.0 84526.0 118330.0 111363.0 98278.0 70659.0 94652.0 74424.0 88345.0 False True 83175.03127205526 103446.18641544183 83405.1300116928 91050.84668027583 95902.16971530426 92132.66112392116 76947.51411537947 80025.70828658104 78357.90070039261 85252.06844012525 0.9756365187839549 1.213415560563141 0.9783355587468285 1.0680192087564797 1.1249248431157872 1.0807088063631949 0.9025882365472658 0.9386952099911239 0.9191319593075375 1.0 16.379447217699273 -7.254054608864677 24.532412833067703 0.9349951175878034 1.0776280376495366 0.4771306157344619 0.06824917597791524 353.5678574064896 1174564.8638880488 0.025092914234268605 0.01903299807428152 5.571156919325333e-08 7.254054608864677 0.14263292006173323 ALIVLAHSER ddPTM_PC-9_Lapatinib_30min_R1 2 ALIVLAHSER 10 0 B4DLR8;P15559-3;P15559-2;P15559;H3BRK3 B4DLR8 NQO1 NAD(P)H dehydrogenase [quinone] 1 0 ; 145.25 0.00011499999999999999 28493000.0 94446.0 86661.0 103728.0 90736.0 102465.0 110587.0 94372.0 89904.0 98943.0 93691.0 False True 93099.18272072494 86460.34177893616 95199.8842416593 97409.028126423 96438.21015394093 105857.45180088806 99258.12039425761 94081.26805068804 87798.99742401979 109885.36451458959 0.847239149016647 0.7868230875045852 0.8663563583940199 0.8864604358980845 0.8776256108349783 0.9633444114100678 0.9032879021944639 0.856176511460694 0.7990053799417722 1.0 16.745639722887113 -5.492247502796562 3.6260888834311094 0.893688872441871 0.8171635270140654 0.2599840822335652 0.053712659865297774 0.3238959926117024 8.897545143882223 0.014770046241907146 0.03126593743642329 3.2192336392316197e-06 5.492247502796562 -0.07652534542780565 ALLETAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 ALLETASPR 9 0 Q96BT3;H3BMP6;H3BQS6;H3BN05;H3BTS2;H3BQJ0;I3L4F8;H3BUW2;H3BTR4;Q96BT3-3;Q96BT3-2 Q96BT3 CENPT Centromere protein T 1 ALLET(0.009)AS(0.991)PR 97.565 0.007662100000000001 0.0 41648.0 40444.0 48643.0 64507.0 55058.0 58967.0 38571.0 53578.0 44043.0 46147.0 True False 54891.197667784705 53516.73207447373 47997.96203722844 49635.907773215156 47414.14707025872 55279.78416832107 42003.7442780721 45298.751199958126 46371.02306443344 44531.40757605363 1.2326400770970007 1.2017749940437967 1.077845158055119 1.1146269672352873 1.0647349736089469 1.2413661992136824 0.9432386390736781 1.0172315151411726 1.041310517419374 1.0 15.442535593641024 -1.52287878101569 0.20605717314051883 0.983727939037774 2.209663466048684 0.4959136805398655 0.0689561280408178 45.612361787200065 0.5613627045741086 0.12319924558962306 18.217306892827636 0.0299999975314894 1.52287878101569 1.22593552701091 ALLFVPR ddPTM_PC-9_AZD4547_30min_R2 2 ALLFVPR 7 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ; 136.44 0.016439 9796600.0 37334.0 34257.0 43669.0 55497.0 46191.0 42148.0 35484.0 44830.0 36252.0 42148.0 False True 49205.43540455903 45329.905317853016 43089.92052718228 42703.024070102794 39778.17696469757 39512.478897118686 38642.007258383535 37902.55359091647 38168.206710075196 40672.41134885278 1.2097988236428214 1.1145123638982768 1.0594385505593509 1.0499260470158303 0.9780137357363635 0.9714810995152169 0.950079082524658 0.9318983638767108 0.938429894964951 1.0 15.311762906073728 -4.707111725140891 0.5433160635407683 0.945544587583328 1.3993884020725391 0.9299141410371606 0.022342845189902132 1.0193708540075554 0.21667389081134114 0.012633546685612623 0.2996324023662529 1.9628552543233907e-05 4.707111725140891 0.4538438144892111 ALLFVPR ddPTM_PC-9_Lapatinib_30min_R1 2 ALLFVPR 7 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ; 136.44 0.016439 30098000.0 37734.0 37487.0 40459.0 39631.0 38693.0 39777.0 40914.0 37751.0 32218.0 32243.0 False True 37195.906240431876 37400.201154694405 37132.61719625643 42545.595945140456 36417.153813364894 38075.83043471583 43032.32672626052 39505.0492768011 28589.26956941945 37816.15958890306 0.9835981930684153 0.9890005109262678 0.9819245951974667 1.1250638988107409 0.9630050806124508 1.0068666635807453 1.1379348721303821 1.0446605288918243 0.7560066881516126 1.0 15.206715237724241 -8.230729699385371 24.87559752352847 0.8780032865382431 1.0299986362229785 0.3710145241903505 0.07863661359736442 556.6345850441015 450889.08866621647 0.05144291514773524 0.019438978672236665 5.878551139366898e-09 8.230729699385371 0.15199534968473538 ALLLLCGEDD ddPTM_PC-9_Lapatinib_30min_R1 2 ALLLLCGEDD 10 0 D6RBE9;P08758;D6RBL5 D6RBE9 ANXA5 Annexin;Annexin A5 0 ; 94.887 0.028239999999999998 4900400.0 43466.0 42977.0 55491.0 47811.0 47642.0 45840.0 47544.0 45391.0 52050.0 39919.0 False True 42846.16686931185 42877.48939699904 50928.74418145445 51327.18043282052 44839.791227775844 43879.53005825915 50005.595685421344 47500.031567992366 46187.58088920117 46818.945961276 0.9151459091956056 0.9158149231395141 1.0877806651943356 1.096290815160027 0.9577274820510245 0.9372173840596916 1.0680632521454247 1.0145472221284029 0.9865147525406268 1.0 15.514804834854624 -5.231122135363925 23.52035563134824 1.0185096696588616 0.9154802890063156 0.40467867669204194 0.0499890528655268 354.9398817599352 275362.13870570593 0.01366783994492872 0.0361449818281018 5.8732415785120354e-06 5.231122135363925 -0.10302938065254597 ALLPLCK ddPTM_PC-9_Lapatinib_30min_R1 1 ALLPLCK 7 0 Q9H1R2-3;Q9H1R2-4;Q9H1R2-2 Q9H1R2-3 0 106.84 0.046056 6282300.0 59272.0 66968.0 62184.0 66328.0 64272.0 70298.0 56914.0 51563.0 68048.0 61050.0 False True 58426.77041084645 66812.93971050179 57071.471557181554 71205.98238372177 60491.64732361381 67291.51841264182 59860.728437659265 53958.805219986134 60383.71766279267 71602.41115598842 0.8159888677989019 0.9331101932440152 0.797060750270676 0.9944634717481369 0.8448269596931672 0.9397940282492001 0.8360155401366376 0.7535892206539657 0.8433196129561137 1.0 16.127720549500122 -9.898401604089221 8.870606713385076 1.0000054610249476 0.8639225323014138 0.2623210026986057 0.06934972845228124 0.0 0.0 0.06696033176593871 0.016240265917492173 1.2635673514624075e-10 9.898401604089221 -0.13608292872353378 ALLQS(ph)SASR ddPTM_PC-9_AZD4547_30min_R2 1 ALLQSSASR 9 0 Q9UQ80;Q9UQ80-2 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 1 ALLQS(0.893)S(0.107)ASR 90.149 0.008796600000000002 5410400.0 52249.0 48817.0 68859.0 79635.0 76827.0 76253.0 58374.0 73109.0 60448.0 75585.0 True False 68863.09515328676 64596.14058153456 67945.8846683286 61276.381098485304 66160.89718055089 71484.88785569875 63569.17291457779 61811.68392768925 63643.15787296213 72938.79215628363 0.9441216822693745 0.8856211992532926 0.9315466113387663 0.8401068798505787 0.9070742087254481 0.9800667894599948 0.8715413435743514 0.8474459488614415 0.872555686644714 1.0 16.15439868884004 ALLQSS(ph)ASR ddPTM_PC-9_AZD4547_30min_R2 2 ALLQSSASR 9 0 Q9UQ80;Q9UQ80-2 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 1 ALLQS(0.229)S(0.771)ASR;ALLQS(0.232)S(0.768)ASR 80.916 0.017991 22004300.0 75510.0 95181.0 99673.0 136058.0 121900.0 120809.0 100581.0 132193.0 91786.0 103225.0 True False 99520.6092944299 125946.39688409865 98351.2708948187 104691.93017514537 104976.28914716371 113254.79413215365 109532.51414878476 111765.60934294043 96637.62057516705 99611.12416924482 0.9990913176056407 1.2643808403377592 0.9873522833425155 1.0510064116661104 1.053861102589337 1.136969340289017 1.0996012248861176 1.1220193555194142 0.9701488802693801 1.0 16.60401924521267 -8.266714359017845 24.843659096533447 0.9850744244862972 1.0912005614906606 0.2370482757389858 0.07471980289812188 598.6077936680296 2819218.9041252327 0.062313709942722846 0.01802581928054534 5.411101009007734e-09 8.266714359017845 0.10612613700436335 ALLQSS(ph)ASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ALLQSSASR 9 0 Q9UQ80;Q9UQ80-2 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 1 ALLQS(0.084)S(0.916)ASR;ALLQS(0.03)S(0.97)ASR;ALLQS(0.04)S(0.96)ASR;ALLQS(0.226)S(0.774)ASR 103.21 0.002928 29591000.0 209705.0 240188.0 252890.0 245499.0 276588.0 253892.0 258776.0 224280.0 221799.0 166774.0 True False 245203.91463745342 264032.2772928076 258919.8566906661 231744.4869484973 222392.5669035716 240577.45656867808 234262.8639040023 218392.88764430254 225042.39077251658 197008.80601774208 1.2446342861210529 1.340205458983542 1.3142552453586693 1.1763153720531 1.1288458186155572 1.2211507771231929 1.189098440010368 1.1085437857261804 1.1422960999634193 1.0 17.587900592007742 -1.522878745303754 0.06923901136741256 0.7679213880917007 2.175219445875128 0.7396375721076505 0.04861520177147359 134.42230972041594 0.6905922798975991 2.482276023725638 18.48305348503189 0.02999999999838245 1.522878745303754 1.4072980577834273 ALLQSS(ph)ASR ddPTM_PC-9_Lapatinib_30min_R1 4 ALLQSSASR 9 0 Q9UQ80;Q9UQ80-2 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 1 ALLQS(0.225)S(0.775)ASR;ALLQS(0.229)S(0.771)ASR;ALLQS(0.002)S(0.998)ASR;ALLQS(0.025)S(0.9)AS(0.075)R 158.47 0.00011567 41881100.0 313686.0 297430.0 303930.0 267022.0 304683.0 295189.0 268903.0 228468.0 309618.0 220315.0 True False 309212.7801170329 296741.3191090443 278942.0486037282 286659.68863927986 286762.1449698255 282564.45458916784 282825.4815875156 239083.45734343954 274745.56041791895 258396.1541987153 1.196661695975699 1.1483968096554578 1.0795131586564264 1.1093806311793208 1.1097771399078016 1.0935319663150493 1.0945421477519877 0.9252593487114222 1.0632726375897623 1.0 17.97922507248827 -5.329693994314864 0.2504041156824906 0.97824065165583 1.2946119259928874 0.6023153821791388 0.04504247617476708 5.401729378167948 0.3666981690015129 0.0719348431814804 0.5228204656392894 4.680648255338124e-06 5.329693994314864 0.3163712743370575 ALLS(ph)SPEGEEK ddPTM_PC-9_AZD4547_30min_R2 1 ALLSSPEGEEK 11 0 A0A499FJI4;O75592-2;O75592;H7C3U4 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 ALLS(0.957)S(0.043)PEGEEK 167.2 0.0020283000000000002 3236500.0 59876.0 62305.0 69678.0 70511.0 67276.0 72050.0 68406.0 75919.0 68690.0 70344.0 True False 78915.32250183157 82443.87280931883 68754.02419320359 54255.77833409049 57935.88866829021 67544.70211012145 74494.00148001875 64187.462995065536 72320.81316658568 67881.2779710471 1.1625491573021172 1.2145303576117559 1.0128569503733966 0.799274556339847 0.8534884787083882 0.9950416982268778 1.09741601376144 0.9455841862971841 1.0654014675067276 1.0 16.05072610567246 -5.350107809934956 4.678005818102347 0.961513808455824 1.188054405785787 0.5149815717744752 0.08500594695710041 0.1744629120497274 6.513288120105015 0.02471635692610042 0.05445705185375298 4.465727204861335e-06 5.350107809934956 0.2265405973299629 ALLSS(ph)PEGEEK ddPTM_PC-9_Lapatinib_30min_R1 1 ALLSSPEGEEK 11 0 A0A499FJI4;O75592-2;O75592;H7C3U4 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 ALLS(0.109)S(0.891)PEGEEK 144.1 0.00016813 4761600.0 49824.0 70763.0 53483.0 57745.0 52306.0 50466.0 46916.0 64878.0 53434.0 52656.0 True False 49113.50062339745 70599.15262116582 49085.83419035026 61991.759931673034 49229.46391755266 48307.68682199187 49345.08091824895 67892.46872878344 47415.70023503508 61757.51944029033 0.7952634929076511 1.1431669092445325 0.7948155080582281 1.0037929064105169 0.7971412123368993 0.7822154655790166 0.7990133244577249 1.0993393087043373 0.7677720974670704 1.0 15.914327185862343 ALLT(ph)PVAIAAGR ddPTM_PC-9_AZD4547_30min_R2 1 ALLTPVAIAAGR 12 0 P00390-5;P00390-4;P00390-2;P00390-3;P00390 P00390-5 GSR Glutathione reductase, mitochondrial 1 ALLT(1)PVAIAAGR 79.744 0.036799 4277600.0 18293.0 21394.0 19472.0 33301.0 29153.0 25101.0 20354.0 23532.0 18941.0 24431.0 True False 24109.793481962784 28309.192117527717 19213.788557221225 25623.96894532125 25105.60916740986 23531.430501959177 22165.466569077278 19895.670111564727 19942.182591182114 23575.678126217645 1.0226553549334036 1.2007795477172767 0.8149834950390792 1.0868815229041398 1.0648944659407626 0.9981231664250938 0.9401836269739311 0.8439065890299666 0.845879490058237 1.0 14.525011648446043 -7.3131945996886465 2.4440846402601486 0.8850024300543278 1.0364311604672445 0.2821012616083063 0.09852421346300998 0.36715094511713425 4.302331218648591 0.04722669888361512 0.0300369922448162 4.861893040340711e-08 7.3131945996886465 0.1514287304129167 ALLT(ph)PVAIAAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALLTPVAIAAGR 12 0 P00390-5;P00390-4;P00390-2;P00390-3;P00390 P00390-5 GSR Glutathione reductase, mitochondrial 1 ALLT(1)PVAIAAGR 94.402 0.012029999999999999 4109400.0 12360.0 11081.0 13523.0 16676.0 19129.0 17394.0 12210.0 16483.0 13285.0 13397.0 True False 14452.303878872353 12181.048448222245 13845.439606263099 15741.697784321454 15380.80976867548 16481.82801961302 11053.380407255183 16050.338715182115 13479.267992249233 15825.770049406345 0.9132133118169808 0.769697045400908 0.8748667245283567 0.9946876351152313 0.9718838148575554 1.0414550425134785 0.6984418687209357 1.014190062478773 0.8517290438423163 1.0 13.949988079483076 -5.531677491233203 22.439406574191075 0.9351034139957457 0.83666185797417 0.13976043980069508 0.09999219725168132 98.48574497726258 251165.81432199434 0.02650042943474259 0.0460378126806428 2.939831972187039e-06 5.531677491233203 -0.09844155602157567 ALLT(ph)PVAIAAGR ddPTM_PC-9_Lapatinib_30min_R1 2 ALLTPVAIAAGR 12 0 P00390-5;P00390-4;P00390-2;P00390-3;P00390 P00390-5 GSR Glutathione reductase, mitochondrial 1 ALLT(1)PVAIAAGR;ALLT(1)PVAIAAGR 100.02 0.0077343 6936000.0 43074.0 40702.0 48648.0 38210.0 49589.0 47653.0 35929.0 40624.0 49260.0 34609.0 True False 42459.75686119584 40607.75701972342 44648.34922671059 41020.09086482341 46672.27251572514 45614.992274568554 37789.22781805283 42511.53934520326 43711.820069203626 40591.11953640626 1.0460356192716882 1.0004098798827719 1.099953628691256 1.0105681078353212 1.1498148621859194 1.1237677796409724 0.930972790345425 1.0473113289490468 1.0768813614514476 1.0 15.308876510847623 -10.424739141616046 10.148172276233513 0.9999976653160411 1.0535277780176506 0.06664454837551814 0.060569923171957196 0.0 0.0 0.05986095586385191 0.014518414345711666 3.7606321831968776e-11 10.424739141616046 0.05353011270160957 ALLTPVAIAAGR ddPTM_PC-9_Lapatinib_30min_R1 1 ALLTPVAIAAGR 12 0 P00390-5;P00390-4;P00390-2;P00390-3;P00390 P00390-5 GSR Glutathione reductase, mitochondrial 0 94.40899999999999 0.022659000000000002 3491000.0 16478.0 15731.0 23074.0 18609.0 13364.0 17195.0 18580.0 13731.0 20760.0 17037.0 False True 16243.02069830489 15694.575836009755 21176.944788215744 19977.56793780419 12577.955794634901 16459.609933502743 19541.981487361783 14368.99238747996 18421.79018750848 19981.822749624473 0.8128898400227353 0.7854426511867998 1.0598104614161754 0.9997870658811463 0.6294698913226665 0.8237291532281296 0.9779879309423383 0.7191031853062556 0.9219274146476296 1.0 14.28640057188401 -8.52545605963539 24.526651536741046 1.0000000134520008 0.8544349468796586 0.1257912937459571 0.12446863893825275 455.8282638064105 4337847.174189829 0.12382258203401632 0.03197085315580464 2.982249265991686e-09 8.52545605963539 -0.14556506657234225 ALLYLCGGDD ddPTM_PC-9_Lapatinib_30min_R1 1 ALLYLCGGDD 10 0 P07355;P07355-2;A6NMY6 P07355 ANXA2;ANXA2P2 Annexin A2;Putative annexin A2-like protein 0 105.2 0.011493999999999999 2435200.0 33667.0 32095.0 35132.0 33253.0 35160.0 32319.0 37847.0 33942.0 32491.0 31153.0 False True 33186.902406228364 32020.68599941093 32243.58257344179 35698.536548756136 33091.95792721964 30936.791709268717 39806.532473206746 35519.06923136298 28831.52143460201 36537.75454123677 0.9082906933641308 0.8763725741074798 0.8824730194366885 0.9770314841998984 0.9056921626059922 0.8467075247974868 1.089463021825296 0.9721196520513022 0.789088486597132 1.0 15.15710035418908 ALMTSHGS(ph)VEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALMTSHGSVEGR 12 0 Q9H8V3-2;Q9H8V3-4;Q9H8V3;Q9H8V3-3;H7C103 Q9H8V3-2 ECT2 Protein ECT2 1 ALMT(0.001)S(0.094)HGS(0.906)VEGR 60.937 0.040149000000000004 2975900.0 10363.0 11717.0 15353.0 17960.0 16701.0 14157.0 11142.0 11305.0 10705.0 10287.0 True False 12117.251221420242 12880.186325044675 15719.073746576742 16953.759427105626 13428.558939131639 13414.581998025846 10086.549098905596 11008.255728637614 10861.540373129701 12151.951668152798 0.9971444548431263 1.0599273825948794 1.2935431423556818 1.3951470422267358 1.1050536823911592 1.1039035016228778 0.8300353206094374 0.905883764950076 0.8938103664117641 1.0 13.568900416495588 -7.06444181871004 2.9916218241528845 0.9000688345279398 1.1818251233837995 0.5410748545670878 0.1138834088788589 0.2177514350061904 3.8322544539101013 0.051071425981562286 0.03961302961326841 8.621010643830212e-08 7.06444181871004 0.2817562888558597 ALNHSVEDIEPDLLT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 ALNHSVEDIEPDLLTPR 17 0 I3L2K5;Q8IWR0 I3L2K5 ZC3H7A Zinc finger CCCH domain-containing protein 7A 1 ALNHSVEDIEPDLLT(1)PR;ALNHSVEDIEPDLLT(1)PR;ALNHS(0.001)VEDIEPDLLT(0.999)PR 198.45 5.0487e-12 11396900.0 37384.0 38395.4 49541.0 59133.0 50976.0 50299.0 39151.0 49885.0 39646.0 44867.0 True False 49271.334364494396 50805.96218703022 48884.053970485664 45500.800445742774 43898.86230980976 47153.79557858433 42635.36315446321 42176.4194932605 41741.60662108686 43296.21998645192 1.1380054512821716 1.173450296652415 1.1290605504541105 1.0509185434659354 1.013919051675791 1.0890972836275201 0.9847363850193965 0.9741362988837866 0.9640935544522934 1.0 15.401953454273954 -5.947747540627942 0.5833685666270948 0.9765645608280178 1.1924973063677653 0.8099499101833436 0.03141574726702982 0.5440340143411119 0.33210066804479377 0.02226910012085257 0.06788427292101333 1.1278528969003957e-06 5.947747540627942 0.2159327455397475 ALNHSVEDIEPDLLT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ALNHSVEDIEPDLLTPR 17 0 I3L2K5;Q8IWR0 I3L2K5 ZC3H7A Zinc finger CCCH domain-containing protein 7A 1 ALNHSVEDIEPDLLT(1)PR;ALNHSVEDIEPDLLT(1)PR;ALNHSVEDIEPDLLT(1)PR;ALNHSVEDIEPDLLT(1)PR 207.17 4.7807e-17 15254200.0 45328.3 42599.7 48934.6 51395.0 58478.6 50720.4 52724.9 49406.3 46209.5 39944.8 True False 53001.48591526618 46828.71668439066 50101.38644950396 48515.504774838155 47020.13812214257 48060.532935838804 47730.41577678044 48109.43697530197 46885.226517714786 47186.47603713718 1.123234671594302 0.9924181803179166 1.061774276385307 1.0281654586084155 0.9964748815981999 1.0185234620617507 1.0115274499247446 1.0195598615467363 0.9936157656870731 1.0 15.526085812232457 -4.753798680846281 24.999957869311583 1.0156938551228794 1.1232348633871847 0.7312179939094143 0.019910113853701346 145.0509843236021 474559.9143798582 0.00493440268271723 0.05105008559043524 1.7627930076440166e-05 4.753798680846281 0.10754100826430535 ALNHSVEDIEPDLLT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 ALNHSVEDIEPDLLTPR 17 0 I3L2K5;Q8IWR0 I3L2K5 ZC3H7A Zinc finger CCCH domain-containing protein 7A 1 ALNHSVEDIEPDLLT(1)PR;ALNHSVEDIEPDLLT(1)PR;ALNHSVEDIEPDLLT(1)PR 165.03 5.7113999999999996e-05 9804000.0 44577.0 36203.6 52959.2 43385.9 48284.4 47269.2 39982.8 33352.3 47928.2 39275.2 True False 43941.32380557938 36119.772788542556 48605.099004423835 46576.643817119664 45444.406522782825 45247.60650588707 42052.91374665709 34901.969616557275 42530.02140967937 46063.865989085556 0.9539217532456112 0.7841237814711607 1.0551676017801113 1.0111318886729048 0.986552160722908 0.9822798311502581 0.9129262784113946 0.7576865047503177 0.9232838038334972 1.0 15.491347876421134 -7.520539228391727 24.97885876006187 0.8713523785694519 0.9604880310960336 0.10074036044221946 0.08717667214876794 170.52844024312935 1820787.7352662578 0.04075147269162024 0.02403302451236671 3.0162044170356533e-08 7.520539228391727 0.08913565252658173 ALPAAHIPAPPHEGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 ALPAAHIPAPPHEGSPR 17 0 P17029;E9PC66 P17029 ZKSCAN1 Zinc finger protein with KRAB and SCAN domains 1 1 ALPAAHIPAPPHEGS(1)PR;ALPAAHIPAPPHEGS(1)PR 125.23 2.2043000000000002e-05 8407300.0 14364.2 22885.0 24693.4 29376.0 30729.0 25954.0 21768.9 28692.0 21424.0 24325.5 True False 18931.716806079345 30282.128709433564 24365.949381619077 22603.817054675725 26462.808771150045 24331.09227711439 23706.289928052793 24258.310676568708 22556.428902037154 23473.87164910594 0.806501675099702 1.2900355408813413 1.038003008018795 0.9629351899236719 1.1273303853204781 1.0365180759621773 1.0099011480688447 1.0334175392618987 0.9609164282405998 1.0 14.518768191087155 -7.664258001151958 1.3416925991191508 0.9873824983137599 1.0544007094119967 0.029861693031268177 0.11554544517212324 1.612396735778416 5.411554163530556 0.0872054228729845 0.036287368185476204 2.166416720131113e-08 7.664258001151958 0.0670182110982368 ALPAAHIPAPPHEGS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALPAAHIPAPPHEGSPR 17 0 P17029;E9PC66 P17029 ZKSCAN1 Zinc finger protein with KRAB and SCAN domains 1 1 ALPAAHIPAPPHEGS(1)PR 120.11 5.0966000000000006e-05 4400000.0 15037.0 12964.0 14950.0 14689.0 16544.0 11579.0 14171.0 13722.0 12062.0 11074.0 True False 17582.467105712272 14250.980243908782 15306.464698190732 13866.022952380546 13302.321962097702 10971.776856335475 12828.620290844648 13361.812039660806 12238.383930937933 13081.628538264227 1.3440579706328561 1.0893888480493203 1.1700733324921113 1.0599615263361086 1.0168704854436081 0.8387164353614414 0.9806592698547034 1.0214180903071075 0.9355397835323198 1.0 13.675254533369193 -3.673737368599218 0.509880434339747 0.9549645304830183 2.2620091031710103 0.740966560267891 0.06622561955008564 6.6076040732238015 0.5533085377690633 0.038805122300216724 6.599851336188465 0.00021196425616307044 3.673737368599218 1.307044572687992 ALPAAHIPAPPHEGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 ALPAAHIPAPPHEGSPR 17 0 P17029;E9PC66 P17029 ZKSCAN1 Zinc finger protein with KRAB and SCAN domains 1 1 ALPAAHIPAPPHEGS(1)PR;ALPAAHIPAPPHEGS(1)PR;ALPAAHIPAPPHEGS(1)PR 97.713 0.00080871 9474500.0 30412.7 35142.0 33578.1 25005.1 28962.199999999997 29597.7 28170.0 28149.1 31986.0 24558.0 True False 29979.009320993868 35060.63085811806 30817.438233214303 26844.05846856831 27258.700337876024 28331.875366608576 29628.504763131423 29457.00994934179 28383.399852487764 28802.81757852192 1.0408359959669025 1.217263927827066 1.0699452631396267 0.9319941840893287 0.946390062832001 0.9836494394817636 1.0286668893540891 1.0227127908245928 0.9854383091206009 1.0 14.813922326902235 -5.543014190336998 6.848893318474423 0.9872755322070258 1.1329074374774946 0.5945615392508437 0.04846393152261608 0.09547495772586502 18.470422735617316 0.013057535841604833 0.023430078986688026 2.8640843859714594e-06 5.543014190336998 0.14563190527046876 ALPASET(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 ALPASETPK 9 0 O76021;J3QSV6;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 ALPAS(0.001)ET(0.999)PK;ALPAS(0.01)ET(0.99)PK;ALPAS(0.002)ET(0.998)PK;ALPAS(0.008)ET(0.992)PK 107.03 0.006186 133137000.0 1102740.0 1124990.0 801440.0 789480.0 803740.0 945370.0 1001240.0 1026660.0 980750.0 879890.0 True False 1453388.3815831 1488621.017121508 790812.3819484068 607477.5833444098 692154.5745622752 886255.8644530963 1090348.4203411108 868013.2872998079 1032590.4427591924 849085.3189176728 1.7117106481545705 1.7532054599872835 0.9313697508708001 0.7154494016205111 0.8151767073826728 1.0437771619733158 1.2841447096635419 1.0222921866159016 1.216120947745785 1.0 19.695550002296407 -5.259225775930046 24.989665878834707 0.9987797316659787 1.7324581337277498 0.7722629672147073 0.15831634959844448 92.79645164489209 1047573.9003471271 0.046326029183915325 0.11090722019454648 5.5052142336825354e-06 5.259225775930046 0.7336784020617712 ALPASET(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ALPASETPK 9 0 O76021;J3QSV6;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 ALPAS(0.049)ET(0.951)PK;ALPAS(0.466)ET(0.534)PK;ALPAS(0.002)ET(0.998)PK;ALPAS(0.01)ET(0.99)PK 119.03 0.004308600000000001 86754000.0 1033840.0 1122030.0 774610.0 846980.0 868970.0 564408.0 806010.0 513850.0 481042.0 526810.0 True False 1208848.6927292387 1233417.723162064 793079.6401247839 799526.4565462105 698701.5664533409 534809.4508965012 729658.8977929354 500361.98196907947 488076.3292079455 622316.4827743358 1.9424982724868483 1.9819782334277745 1.274399219813643 1.28475860543153 1.1227431472463567 0.8593850005583632 1.172488465258157 0.8040313824541918 0.7842895740637672 1.0 19.247288932620762 -5.2536130941541 0.739947695236397 0.9087371135299092 2.363652554524398 0.8794381499116612 0.14158452681212982 0.5102453443555914 0.3283322210611023 0.06207371875251129 0.5546458702237104 5.576823577737832e-06 5.2536130941541 1.4549154409944889 ALPASET(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 ALPASETPK 9 0 O76021;J3QSV6;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 ALPASET(1)PK;ALPAS(0.002)ET(0.998)PK;ALPAS(0.006)ET(0.994)PK;ALPAS(0.038)ET(0.962)PK 108.35 0.0059698 161652000.0 1346910.0 1520430.0 1161950.0 1285090.0 1121020.0 940700.0 1018280.0 888810.0 866990.0 816800.0 True False 1327702.8164069569 1516909.5377499405 1066418.956256709 1379599.8055345668 1055083.8076101192 900468.4538788032 1071001.5559176952 930107.3573604306 769340.456390558 957982.7916824121 1.3859359770703619 1.5834413216190864 1.113192184155898 1.4401091726415143 1.1013598749067068 0.9399630783527937 1.117975777035409 0.9709019467113531 0.8030837955235501 1.0 19.86964021539052 -6.197736006206765 0.6849995620839396 0.9253933697227358 1.492778442004328 0.6795329099892662 0.13291801688689553 0.4889440978468452 0.4811662903038106 0.0807389134289749 0.16192099075847594 6.34255137612534e-07 6.197736006206765 0.5673850722815922 ALPAVQQNNLDEDLIR ddPTM_PC-9_Lapatinib_30min_R1 1 ALPAVQQNNLDEDLIR 16 0 P22314;P22314-2 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 190.34 1.0972000000000002e-07 3295600.0 5125.2 5658.4 6380.7 4630.4 6011.7 7771.4 2590.7 6841.2 7045.7 5450.8 False True 5052.113708153427 5645.298322451059 5856.103476214277 4970.935062561584 5658.103625456947 7439.035338018222 2724.8337696075446 7159.067127028471 6252.13907148981 6392.963517265541 0.790261620375141 0.8830487311877732 0.9160232903564426 0.7775634960431934 0.8850517620155426 1.1636286235526834 0.42622388853753956 1.1198354421535344 0.9779719616113239 1.0 12.642269145497405 ALPDSQQVPSS(ph)PASK ddPTM_PC-9_AZD4547_30min_R2 2 ALPDSQQVPSSPASK 15 0 O14924-5;O14924-4;O14924;O14924-6;O14924-7;O14924-2;O14924-3 O14924-5 RGS12 Regulator of G-protein signaling 12 1 ALPDSQQVPS(0.007)S(0.993)PASK;ALPDSQQVPS(0.014)S(0.986)PASK 262.83 2.0250999999999994e-61 48665000.0 111401.0 125564.0 148765.0 215140.0 220115.0 173736.0 153591.0 191130.0 163409.0 174521.0 True False 146824.2007152533 166150.10746215048 146792.27889867584 165542.79687986567 189555.83171146756 162872.26045529573 167260.3014548072 161595.25023046753 172046.4661339147 168411.07291005852 0.871820351109966 0.9865747221436234 0.8716308040925053 0.9829686018821062 1.1255544450613506 0.967111352246293 0.993166889591245 0.9595286547266935 1.0215864263616308 1.0 17.361627472147838 -5.953128543515925 8.461075386556024 1.0103627599314564 0.9188505284052882 0.425977550936247 0.05223484270405166 0.28387988090413097 46.28027141491782 0.014726494842544067 0.021852655020642243 1.1139647708440676e-06 5.953128543515925 -0.09151223152616816 ALPDSQQVPSS(ph)PASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ALPDSQQVPSSPASK 15 0 O14924-5;O14924-4;O14924;O14924-6;O14924-7;O14924-2;O14924-3 O14924-5 RGS12 Regulator of G-protein signaling 12 1 ALPDSQQVPS(0.117)S(0.879)PAS(0.004)K;ALPDSQQVPS(0.169)S(0.831)PASK;ALPDSQQVPS(0.025)S(0.942)PAS(0.033)K;ALPDSQQVPS(0.212)S(0.788)PASK 246.75 3.1756e-40 42586100.0 163185.0 187002.0 211458.0 243730.0 258153.0 234563.0 230147.0 225571.0 211637.0 167348.0 True False 190808.99744933535 205566.32270683616 216499.96067893083 230074.5982833211 207569.77281681678 222262.10335543792 208345.81004001293 219650.0002622308 214731.79074713215 197686.86767396095 0.9652082593773044 1.0398582623397654 1.095166124216191 1.1638334958231837 1.0499927246515708 1.1243139515064207 1.0539183127916796 1.1111006150620637 1.0862218278519284 1.0 17.592857510547297 -4.896714826068566 2.5480396951058832 1.090990486627504 0.954265015547346 0.42472765008780344 0.0427565805335177 0.33396132170099185 3.3883326370088827 0.010528319266273302 0.08976928142955015 1.2684845266327922e-05 4.896714826068566 -0.13672547108015798 ALPDSQQVPSS(ph)PASK ddPTM_PC-9_Lapatinib_30min_R1 3 ALPDSQQVPSSPASK 15 0 O14924-5;O14924-4;O14924;O14924-6;O14924-7;O14924-2;O14924-3 O14924-5 RGS12 Regulator of G-protein signaling 12 1 ALPDSQQVPS(0.028)S(0.971)PAS(0.001)K;ALPDSQQVPS(0.002)S(0.997)PASK;ALPDSQQVPS(0.011)S(0.989)PASK 241.39 1.2052e-32 42142600.0 229242.0 179519.0 202017.0 187059.0 181032.0 180436.0 163816.0 155419.0 199722.0 146914.0 True False 225972.96704216563 179103.33478511483 185407.94206817076 200815.94287053143 170384.05368260609 172719.1728968597 172297.5909221561 162640.33412495445 177227.20519410248 172307.8891494 1.3114487569761544 1.039437809082687 1.0760270059800472 1.165448337054454 0.9888348962064886 1.0023869118790207 0.9999402335708786 0.9438937179709557 1.028549569430551 1.0 17.394629231578065 -1.5228787452803376 0.5188801008987929 0.9953780275148315 10.63471025965505 0.669178703128719 0.05890722732368476 74.9326626885708 0.7546308166611557 0.03199592497056288 794.4783231075895 0.029999999999999995 1.5228787452803376 9.639332232140218 ALPGQLKPFETLLSQNQGGK ddPTM_PC-9_AZD4547_30min_R2 2 ALPGQLKPFETLLSQNQGGK 20 1 P09211;A0A087X243 P09211 GSTP1 Glutathione S-transferase P 0 ; 131.82 1.5725e-06 8116000.0 42122.0 41148.0 53479.0 59031.0 59709.0 56555.0 45446.0 53887.0 54022.0 45695.0 False True 55515.91980797221 54448.28630700337 52769.833517442166 45422.31496985853 51419.436002362556 53018.6069096172 49490.605959432374 45560.00235007171 56877.49263190119 44095.23195847555 1.259000516433421 1.2347885222211163 1.1967242527975697 1.0300958392198207 1.166099682858777 1.2023659827789268 1.1223573107867455 1.0332183396376171 1.2898785221373295 1.0 15.428335044362756 -1.5228787458417716 0.01756786581728741 4.450052075048178e-10 2.584499375782465 0.27415937994480033 0.08303059027639648 5675.757043190004 7.720312672823337 437.0641788252978 734.2085921156977 0.029999999961217508 1.5228787458417716 2.5844993753374594 ALPGQLKPFETLLSQNQGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALPGQLKPFETLLSQNQGGK 20 1 P09211;A0A087X243 P09211 GSTP1 Glutathione S-transferase P 0 171.78 1.5132e-08 7716700.0 35473.0 43601.0 42397.0 59271.0 55991.0 59908.0 56313.0 57008.0 52604.0 47318.0 False True 41477.878276313844 47929.41913102948 43407.905271517855 55950.238029174696 45019.96548475658 56766.31901799339 50978.62496918604 55511.600404968856 53373.233983009326 55896.37883091812 0.7420494698195202 0.857469126506602 0.7765781286623799 1.0009635543372049 0.80541828337285 1.015563444453294 0.9120201708127127 0.9931162190825781 0.9548603165235248 1.0 15.77046720265556 -2.662376922978043 0.27204614454011344 0.9992081313464021 4.904023997397845e-11 0.5522966684356426 0.06554933355507547 20.094067840023328 0.48608289802207316 0.07150233239860809 8.33984679342475 0.002175820564010943 2.662376922978043 -0.9992081312973619 ALPGQLKPFETLLSQNQGGK ddPTM_PC-9_Lapatinib_30min_R1 4 ALPGQLKPFETLLSQNQGGK 20 1 P09211;A0A087X243 P09211 GSTP1 Glutathione S-transferase P 0 ;;; 120.99 1.3885999999999999e-05 40002100.0 138427.0 123894.0 124906.0 116853.0 124110.0 123992.0 121181.0 104710.0 110503.0 122911.0 False True 136453.00559559712 123607.13105502437 114636.7108311031 125446.75943018058 116810.09380964832 118689.15119946908 127455.15923681318 109575.2088626487 98056.98849182314 144156.0025813869 0.9465648544087446 0.8574539307528234 0.795226759748572 0.8702153027540871 0.8103033638415453 0.8233382521304315 0.8841474302456129 0.7601154783740985 0.6802143978462679 1.0 17.13727138559568 -4.812917816496559 2.9685079333754407 0.8220760774356802 0.9627015257074909 0.164962305383484 0.0792029943243186 0.6045034754822176 8.03964461519335 0.019625511642037553 0.19818812177285333 1.5384457397847286e-05 4.812917816496559 0.14062544827181067 ALPLEAEPPPGPPSPS(ph)VTTEGQAVKPEPT ddPTM_PC-9_Lapatinib_30min_R1 2 ALPLEAEPPPGPPSPSVTTEGQAVKPEPT 29 1 Q8N554-2;Q8N554 Q8N554-2 ZNF276 Zinc finger protein 276 1 ALPLEAEPPPGPPS(0.335)PS(0.484)VT(0.138)T(0.043)EGQAVKPEPT;ALPLEAEPPPGPPS(0.439)PS(0.52)VT(0.033)T(0.008)EGQAVKPEPT 99.219 1.728e-06 2059300.0 24614.0 21199.1 26881.0 16087.5 17215.3 23875.8 22288.0 18985.1 22510.0 17404.5 True False 24262.999846345207 21150.01478641883 24670.94794366073 17270.628416326785 16202.729900582028 22854.687691208193 23441.963583978453 19867.21705451502 19974.686759191507 20412.8446349615 1.1886143396589355 1.036113053552309 1.208599212155188 0.8460667155986198 0.7937516887201148 1.1196228698113195 1.1483927891083303 0.9732703799884914 0.9785351878385655 1.0 14.317189622909115 -5.745889117370896 24.999967647917497 0.9839148356519938 1.1336092751945317 0.32104884067340334 0.10917390298829929 350.93805142252995 564194.369640655 0.03240425890188577 0.055875268591536124 1.7951919107807715e-06 5.745889117370896 0.14969443954253792 ALPLS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 ALPLSPR 7 0 J3KTI7;J3QR52;J3QLN7;Q99741 J3KTI7 CDC6 Cell division control protein 6 homolog 1 ALPLS(1)PR;ALPLS(1)PR 75.043 0.033296 23281000.0 52829.0 42360.0 58268.0 51259.0 55875.0 51021.0 45117.0 42561.0 54418.0 47829.0 True False 52075.64877234794 42261.91802259063 53477.42996098443 55028.757855011325 52588.54235447662 48838.95076576002 47452.937500823544 44538.5394365694 48288.87179305569 56096.17892186352 0.9283279141861732 0.7533831864280336 0.9533168031903431 0.9809715904475597 0.9374710250358997 0.8706288325589501 0.8459210308588191 0.793967437579077 0.8608228353720377 1.0 15.775614882322458 -6.933100255061761 7.2053464395267435 0.8580302489685306 0.9080974388329177 0.0358783136906744 0.0754859319199647 0.6124455627505148 54.78789397316642 0.02745212310609803 0.0241709296875839 1.1665402950360977e-07 6.933100255061761 0.050067189864387074 ALPNNT(ph)SSSPQPK ddPTM_PC-9_AZD4547_30min_R2 1 ALPNNTSSSPQPK 13 0 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;A0A087X1Q1;A0A087WXZ1;A0A087WT22 J3KP33 TP53 Cellular tumor antigen p53 1 ALPNNT(0.355)S(0.163)S(0.163)S(0.32)PQPK 87.258 0.017575999999999998 7464000.0 10258.0 45084.0 12430.0 31456.0 14610.0 18177.0 15895.0 12688.0 14933.0 21767.0 True False 13519.83062034516 59656.521334328296 12265.170078382283 24204.30519035539 12581.653686957023 17040.389316525707 17309.62420730487 10727.361141234629 15722.327893676274 21004.94395535916 0.6436499258973618 2.8401180912985797 0.5839182482204611 1.152314676097003 0.5989853490538338 0.8112561191660812 0.8240738106272608 0.510706487198109 0.7485060625293842 1.0 14.358441316031662 -5.321332748004634 24.999998646120986 0.770950281044611 1.741901829761583 0.35068437593230206 0.5241538212999287 208.1150715828873 86868.52929539878 0.12414531115303623 0.2584291519110317 4.771635401214379e-06 5.321332748004634 0.9709515487169719 ALPNNT(ph)SSSPQPK ddPTM_PC-9_Lapatinib_30min_R1 1 ALPNNTSSSPQPK 13 0 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;A0A087X1Q1;A0A087WXZ1;A0A087WT22 J3KP33 TP53 Cellular tumor antigen p53 1 ALPNNT(0.394)S(0.202)S(0.202)S(0.202)PQPK 84.605 0.020794999999999998 9842200.0 41365.0 40757.0 44931.0 33449.0 36598.0 34721.0 33939.0 39289.0 32917.0 30574.0 True False 40775.12751458803 40662.62967060261 41236.94661867564 35908.951042593 34445.3775944364 33236.063768604174 35696.19535519761 41114.510371546145 29209.540828623165 35858.67516270577 1.1371063579335898 1.1339691019285933 1.149985224818441 1.0014020562572128 0.960587011041076 0.9268625686196795 0.9954688842582466 1.1465708140357238 0.8145738986754891 1.0 15.13003456682149 -5.8040749287493005 5.1311528321437745 0.9805083653033012 1.1403388265080001 0.4838920812125628 0.07701660993754124 0.16375882352107782 9.86078637782678 0.021341419938863637 0.03323753901284507 1.5700918932905282e-06 5.8040749287493005 0.1598304612046989 ALPNNTS(ph)SSPQPK ddPTM_PC-9_Lapatinib_30min_R1 3 ALPNNTSSSPQPK 13 0 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;A0A087X1Q1;A0A087WXZ1;A0A087WT22 J3KP33 TP53 Cellular tumor antigen p53 1 ALPNNT(0.07)S(0.518)S(0.206)S(0.206)PQPK;ALPNNT(0.127)S(0.51)S(0.181)S(0.181)PQPK;ALPNNT(0.07)S(0.31)S(0.31)S(0.31)PQPK 185.95 4.2983000000000005e-05 1127925900.0 359388.0 537261.0 322379.0 362876.0 311936.0 305820.0 286673.0 268934.0 320687.0 264111.0 True False 354263.06121631333 536017.005163718 295874.2430389272 389563.11155884934 293588.5377697719 292740.7915012391 301515.525238238 281429.65543183626 284567.8530761814 309762.2344442144 1.1436612402152373 1.7304143164045076 0.9551656404138308 1.2576197749148352 0.9477867380978128 0.9450499736563571 0.9733772930041878 0.9085344310509208 0.918665419581449 1.0 18.24080173896064 -5.705827707450853 1.188457795763588 0.9445095798489809 1.4201886689004377 0.4495559580449211 0.17915075393938365 0.4369689331938386 1.185006944983852 0.05915790589722115 0.17168069855185064 1.9686671410010673e-06 5.705827707450853 0.47567908905145684 ALPNNTSS(ph)SPQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALPNNTSSSPQPK 13 0 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;A0A087X1Q1;A0A087WXZ1;A0A087WT22 J3KP33 TP53 Cellular tumor antigen p53 1 ALPNNT(0.002)S(0.114)S(0.442)S(0.442)PQPK 204.18 9.9067e-10 609450000.0 49478.0 58741.0 66354.0 70609.0 71091.0 59813.0 63683.0 58337.0 54905.0 45132.0 True False 57853.648164955244 64572.41827425524 67936.13100894618 66653.00664746664 57161.22888101358 56676.30098523131 57650.48521500669 56805.71556316073 55707.881754945 53314.074335284546 1.0851477566903247 1.211170203728355 1.2742626005603253 1.250195327940901 1.0721602052308896 1.0630645226774866 1.0813370753180684 1.0654919225628443 1.0449001028247467 1.0 15.70222881860026 -6.3102856323404595 7.129133105292879 1.0590054863686535 1.2104549783759782 0.6783947656792986 0.05073506960803606 0.15577705597186173 19.49435212210503 0.016425945429227415 0.018749243965631282 4.894568012865207e-07 6.3102856323404595 0.1514494920073246 ALPNNTSS(ph)SPQPK ddPTM_PC-9_Lapatinib_30min_R1 1 ALPNNTSSSPQPK 13 0 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;A0A087X1Q1;A0A087WXZ1;A0A087WT22 J3KP33 TP53 Cellular tumor antigen p53 1 ALPNNT(0.293)S(0.09)S(0.309)S(0.309)PQPK 201.3 2.5566e-07 191940000.0 152730.0 135560.0 140590.0 127360.0 136080.0 126740.0 105950.0 111830.0 120110.0 96800.0 True False 150552.04219274828 135246.11914878167 129031.23289309385 136726.4792605055 128076.04194357351 121319.62564537016 111435.57258266845 117026.03005548636 106581.94698562822 113531.75102210788 1.326078747463619 1.1912625140648572 1.1365211205803367 1.204301686793159 1.128107694900552 1.068596445955861 0.9815366325229032 1.0307779894339695 0.9387853708419741 1.0 16.792736301787315 -6.198773981378109 0.4796867116108089 0.9601402609426715 1.3076866455968617 0.8485022868506564 0.04407747947750222 0.5585463061189141 0.23849403013356107 0.03849802730503263 0.0949273741264443 6.327410613055041e-07 6.198773981378109 0.3475463846541902 ALPNNTSSS(ph)PQPK ddPTM_PC-9_AZD4547_30min_R2 10 ALPNNTSSSPQPK 13 0 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;A0A087X1Q1;A0A087WXZ1;A0A087WT22 J3KP33 TP53 Cellular tumor antigen p53 1 ALPNNT(0.005)S(0.05)S(0.08)S(0.865)PQPK;ALPNNT(0.005)S(0.018)S(0.067)S(0.909)PQPK;ALPNNT(0.025)S(0.294)S(0.294)S(0.387)PQPK;ALPNNT(0.054)S(0.07)S(0.273)S(0.603)PQPK;ALPNNT(0.002)S(0.027)S(0.114)S(0.857)PQPK;ALPNNT(0.032)S(0.032)S(0.019)S(0.917)PQPK;ALPNNT(0.001)S(0.013)S(0.013)S(0.973)PQPK;ALPNNT(0.046)S(0.184)S(0.052)S(0.717)PQPK;ALPNNT(0.19)S(0.19)S(0.19)S(0.431)PQPK;ALPNNT(0.098)S(0.098)S(0.307)S(0.497)PQPK 237.59 4.7456999999999994e-26 11178719400.0 983805.0 962508.0 1142197.0 1457003.0 1314086.0 1202523.0 1048967.0 1284743.0 1076483.0 1193428.0 True False 1296634.5255847825 1273619.8881301926 1127050.7214817381 1121113.4688219544 1131647.8416754676 1127329.0467115853 1142323.0308816573 1086215.489807156 1133383.693696399 1151646.4489712147 1.1258963432250306 1.105912226159286 0.9786429876014047 0.9734875402285694 0.9826347684103813 0.9788846635342361 0.991904270535557 0.9431848557146081 0.9841420469874846 1.0 20.135266452248395 -5.2387242193087795 4.521867781059952 0.9769858050407733 1.1202403521142366 0.9356004814444381 0.014377897251225005 0.03998875588426984 2.117474836455032 0.00363883804761759 0.009677521181592683 5.771328313150083e-06 5.2387242193087795 0.1432545470734633 ALPNNTSSS(ph)PQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 9 ALPNNTSSSPQPK 13 0 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;A0A087X1Q1;A0A087WXZ1;A0A087WT22 J3KP33 TP53 Cellular tumor antigen p53 1 ALPNNT(0.084)S(0.049)S(0.182)S(0.684)PQPK;ALPNNT(0.054)S(0.013)S(0.006)S(0.926)PQPK;ALPNNT(0.061)S(0.072)S(0.026)S(0.842)PQPK;ALPNNT(0.254)S(0.023)S(0.02)S(0.702)PQPK;ALPNNT(0.041)S(0.02)S(0.01)S(0.928)PQPK;ALPNNT(0.035)S(0.185)S(0.068)S(0.712)PQPK;ALPNNT(0.11)S(0.216)S(0.106)S(0.568)PQPK;ALPNNT(0.001)S(0.007)S(0.026)S(0.966)PQPK;ALPNNT(0.023)S(0.076)S(0.031)S(0.87)PQPK 183.06 6.045e-05 8756956000.0 1489015.0 1505810.0 1565169.0 1733816.0 1860089.0 1641343.0 1753138.0 1627312.0 1502172.0 1299138.0 True False 1741075.8301131942 1655296.8652483982 1602488.564896491 1636675.9106273102 1495617.913210614 1555268.083660786 1587068.0770200298 1584596.7842795833 1524138.4236697787 1534661.4354292515 1.1345015844658972 1.0786071944170568 1.0441968032175564 1.0664736031302726 0.974558869261143 1.0134274881454688 1.034148666527298 1.032538348653014 0.9931431053673871 1.0 20.549488984332193 -3.8759997146360865 0.6062938012621641 1.011098470414513 1.4338233873084132 0.7616152793370681 0.021798430880151987 4.819885156315306 0.5909334120714729 0.010438140715611095 1.8206816291538832 0.00013304552921863068 3.8759997146360865 0.42272491689390024 ALPNNTSSS(ph)PQPK ddPTM_PC-9_Lapatinib_30min_R1 4 ALPNNTSSSPQPK 13 0 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;A0A087X1Q1;A0A087WXZ1;A0A087WT22 J3KP33 TP53 Cellular tumor antigen p53 1 ALPNNT(0.014)S(0.051)S(0.195)S(0.74)PQPK;ALPNNTS(0.003)S(0.028)S(0.969)PQPK;ALPNNT(0.005)S(0.005)S(0.005)S(0.986)PQPK;ALPNNT(0.003)S(0.002)S(0.02)S(0.975)PQPK 188.12 3.0303e-05 10020753200.0 522841.0 445332.0 538339.0 443277.0 493468.0 453084.0 424639.0 430288.0 439486.0 393507.0 True False 515385.19146270386 444300.86111511657 494078.8454686356 475877.06930872326 464443.1824354157 433706.65351039026 446624.7296454154 450280.7513235738 389986.4586872522 461524.1606348824 1.1167025161883812 0.9626816947219554 1.0705373360930235 1.0310989324027948 1.006324743208498 0.939726866983029 0.9677168992215466 0.9756385249781032 0.8449968429621941 1.0 18.816046648885873 -6.576755513699181 2.153863280893595 0.9440422621299719 1.0419564111724249 0.4458760480463376 0.052411965169002345 0.30344820005758694 2.854969995404438 0.018587964652144837 0.01933553839987562 2.6499915328661774e-07 6.576755513699181 0.09791414904245299 ALPNNTSSSPQPK ddPTM_PC-9_Lapatinib_30min_R1 1 ALPNNTSSSPQPK 13 0 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;A0A087X1Q1;A0A087WXZ1;A0A087WT22 J3KP33 TP53 Cellular tumor antigen p53 0 141.89 4.7171000000000006e-05 0.0 34470.0 33129.0 22653.0 19515.0 21015.0 19992.0 15833.0 16912.0 20835.0 15726.0 False True 33978.45147897616 33052.29183593969 20790.55778310875 20950.198200131603 19778.939017079665 19136.988763628215 16652.75526853601 17697.793260291382 18488.342897723465 18444.218146422158 1.8422278032732637 1.7920137125655953 1.1272127459163532 1.1358680554423803 1.0723652724155412 1.0375603135739555 0.9028713028839523 0.9595306843475191 1.0023923351454107 1.0 14.170881013787566 -5.287030030449244 2.741183906332228 1.0146500232167264 1.8635610266536726 0.9647288733457322 0.06052333103670602 0.05115316733315019 0.7496525633415269 0.01932914377974563 0.057700361923219604 5.163806615206577e-06 5.287030030449244 0.8489110034369463 ALPQT(ph)PRPR ddPTM_PC-9_AZD4547_30min_R2 2 ALPQTPRPR 9 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 ALPQT(1)PRPR;ALPQT(1)PRPR 121.29 0.0011719 865600000.0 113982.0 114249.0 200869.0 264923.0 309637.0 203110.0 124666.0 214067.0 203931.0 178925.0 True False 150225.9050271185 151177.75498903543 198205.3458145271 203849.09536954877 266649.2472736692 190409.49959176691 135761.03248995726 180987.86392029285 214710.3763266121 172660.89021053116 0.870063306426505 0.8755761354218629 1.1479458120066957 1.1806327137604167 1.5443523252343652 1.1027946129525585 0.786287110673525 1.048227329881181 1.243537989783376 1.0 17.397581806353223 -5.259368659801072 22.511115340354905 1.1365581517063226 0.8728195883750932 0.244897135309325 0.18168887190008196 67.09492519268014 729333.3250100412 0.051523922828354246 0.12281304815592524 5.503403303611208e-06 5.259368659801072 -0.26373856333122936 ALPQT(ph)PRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALPQTPRPR 9 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 ALPQT(1)PRPR 96.756 0.0036061 323510000.0 84544.0 60210.0 94176.0 110950.0 119570.0 113670.0 90971.0 92210.0 83723.0 92618.0 True False 98855.62937988555 66187.25088597252 96421.5130044688 104733.83120475318 96141.11684042678 107708.94509540126 82353.5683069953 89789.58520457076 84947.29048664549 109408.91023631515 0.9035427659992655 0.6049530220437527 0.8812948853635912 0.9572696682430696 0.8787320578622809 0.984462278828643 0.7527135416038573 0.8206789100689506 0.7764202230253974 1.0 16.739370710101895 -12.070816920356 2.1500879949862615 3.4116274125459074 0.8400090156842412 0.1742858594197838 0.10447313383050634 12740927.728949748 441206.847106885 151011375.31925118 0.026993772913794394 8.495385280149816e-13 12.070816920356 -2.571618396861666 ALPQT(ph)PRPR ddPTM_PC-9_Lapatinib_30min_R1 2 ALPQTPRPR 9 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 ALPQT(1)PRPR;ALPQT(1)PRPR 91.469 0.0056058 751090000.0 239909.0 133136.0 180432.0 171275.0 167077.0 163358.0 123739.0 126037.0 206940.0 112035.0 True False 236487.85366607728 132827.7317718515 165597.5774476613 183871.1348566504 157249.8593460202 156371.55914609716 130145.59996042313 131893.13914068966 183632.2380251928 131400.10047274615 1.799753978994312 1.0108647656582384 1.260254572499418 1.399322635181602 1.196725563985665 1.1900413971032722 0.9904528192306579 1.0037521939950553 1.3975045480523067 1.0 17.00360685322854 -6.605444210244047 2.0246044832437624 1.101832149654672 1.3346880294487746 0.22904460621392098 0.2140321065418028 0.5538530139879374 4.627397859406441 0.07939973767559233 0.08115997800144091 2.4805945760436923e-07 6.605444210244047 0.23285587979410272 ALPQTPRPR ddPTM_PC-9_AZD4547_30min_R2 2 ALPQTPRPR 9 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 ; 95.35799999999999 0.007066800000000001 4277500.0 3252.8 3820.8 9201.6 14379.6 12772.9 7766.8 5080.8 9389.8 5831.200000000001 7798.4 False True 4287.122737556907 5055.798880183691 9079.580771781362 11064.605382605372 10999.60331130276 7281.1407682011295 5532.981357186196 7938.822166138468 6139.425327369256 7525.38038964822 0.5696885094943768 0.6718329995834308 1.2065278167560902 1.4703051287381628 1.4616674163652403 0.9675445480758603 0.7352427479675667 1.0549396515635237 0.8158292351326905 1.0 12.877548793097743 -6.989285109334278 24.994395123141945 0.8982686391613591 1.0958971547444463 0.07577376905833766 0.2848162700978438 620.1957715854834 1446711.107165564 0.11412813489650202 0.10055712136921911 1.024978818521679e-07 6.989285109334278 0.19762851558308714 ALPQTPRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ALPQTPRPR 9 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 ;; 109.29 0.0030833 2785600.0 21296.2 24939.3 32601.0 33826.7 38996.3 35439.9 26965.6 35966.5 30263.8 21573.1 False True 24901.226040877158 27415.1088859082 33378.33147998098 31931.499666641077 31355.25495228186 33581.36925562167 24411.223153962368 35022.41748465677 30706.350821515418 25484.13225743437 0.9771266994430559 1.07577172371292 1.3097691984487199 1.2529953676302181 1.2303834651122851 1.3177364218797418 0.9578989352027474 1.3742833042486602 1.2049203995383282 1.0 14.63731160941783 -5.043205019811755 4.701228510157948 1.2167293783981088 0.9946250326825646 0.25575970066615716 0.12644064624222812 0.2218925609752912 11.27629564952563 0.03075057667331375 0.0989407951679856 9.053051275791155e-06 5.043205019811755 -0.22210434571554416 ALPQTPRPR ddPTM_PC-9_Lapatinib_30min_R1 2 ALPQTPRPR 9 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 ; 114.89 0.0026076 2438900.0 17992.8 19503.2 27066.1 21734.7 24752.8 20856.5 14859.6 18270.7 27739.3 18355.0 False True 17736.21937252458 19458.041538673035 24840.82973616738 23333.14234283373 23296.888969877193 19964.516113876132 15628.957379418789 19119.623422469598 24615.00792622127 21527.637293499876 0.8238813730794281 0.9038633117693904 1.1539041371561893 1.0838691689532978 1.0821851303167176 0.9273900262108319 0.7259950159109122 0.8881431418506218 1.143414281401592 1.0 14.393902368724904 -6.884886538439389 8.413221797398593 0.9155517714797865 1.0155924715630273 0.05870203759113768 0.1316113416416515 0.6204427601796705 43.17537121000426 0.049731300065823596 0.04387224195528288 1.3035072816333246e-07 6.884886538439389 0.10004070008324084 ALPSLNTGSS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALPSLNTGSSSPR 13 0 O14545 O14545 TRAFD1 TRAF-type zinc finger domain-containing protein 1 1 ALPSLNT(0.002)GS(0.053)S(0.545)S(0.401)PR;ALPSLNT(0.002)GS(0.042)S(0.478)S(0.478)PR 146.84 0.00010621 165927000.0 542461.0 626097.0 611549.0 653412.0 706808.0 734703.0 598361.0 608690.0 547489.0 483857.0 True False 634288.9332068755 688251.7724290784 626130.6474724979 616803.4440302873 568314.0462636822 696173.8813092879 541679.9143215077 592712.532460364 555494.9908775723 571576.4438900945 1.1097184637105857 1.2041290010919672 1.0954451572760988 1.0791267740713424 0.994292281179034 1.2179891049589011 0.9476946086771633 1.036978585797587 0.9718647379813742 1.0 19.124586934986667 -6.393542793849635 0.4023381308435812 0.9800662834581451 1.1803353624706854 0.36631628415180884 0.0704522524445035 1.9073093495538445 0.5697788740513832 0.06941759347022013 0.1607263109007336 4.0407055686133467e-07 6.393542793849635 0.20026907901254032 ALPSLNTGSS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 ALPSLNTGSSSPR 13 0 O14545 O14545 TRAFD1 TRAF-type zinc finger domain-containing protein 1 1 ALPSLNT(0.001)GS(0.12)S(0.582)S(0.298)PR 97.631 0.0029625999999999997 5499800.0 25040.0 21329.0 33149.0 25171.0 26017.0 29662.0 22161.0 19701.0 34058.0 18624.0 True False 24682.925008226375 21279.614010949845 30423.61717884042 27022.15930799451 24486.731211390023 28393.4254054992 23308.388145394212 20616.380382036463 30222.0293933605 21843.13358507988 1.1300084263132575 0.9742015232413838 1.392822923521445 1.2371008583883862 1.1210264825792153 1.2998787602935116 1.0670807855753437 0.9438380396171107 1.3835940377164515 1.0 14.414892217646276 -7.3058025588011315 24.964679196326493 1.09394803087743 1.1904668885002472 0.0850550838983809 0.15043851699425798 1230.5918976821504 692491.7897849471 0.06259092316029086 0.0421991001011303 4.945354641534244e-08 7.3058025588011315 0.09651885762281709 ALPSLNTGSSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 ALPSLNTGSSSPR 13 0 O14545 O14545 TRAFD1 TRAF-type zinc finger domain-containing protein 1 1 ALPSLNT(0.004)GS(0.014)S(0.085)S(0.898)PR;ALPSLNTGSS(0.008)S(0.992)PR;ALPSLNTGS(0.005)S(0.017)S(0.978)PR;ALPSLNTGSS(0.005)S(0.995)PR 198.81 6.3117e-07 876990000.0 1019016.0 970220.0 1238831.0 1565187.0 1328023.0 1347801.0 1031300.0 1296706.0 1066433.0 1168176.0 True False 1343041.8911504813 1283824.6413138155 1222403.291502204 1204357.3190480906 1143649.9297956026 1263522.7904056078 1123083.7021071746 1096329.8830395464 1122802.47121388 1127278.513805099 1.1914020135246601 1.1388708518716453 1.0843844502775217 1.0683760085010527 1.0145229557647135 1.1208612378680223 0.9962788151760605 0.9725457104109202 0.9960293374384381 1.0 20.104412571830053 -1.5228787452812547 0.2736559505325899 0.9818885655548767 2.542351227748597 0.7688142468560686 0.03375909849908341 24.855001394628076 0.34838370154854265 0.04030581014552119 18.401242002564178 0.02999999999993665 1.5228787452812547 1.56046266219372 ALPSLNTGSSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ALPSLNTGSSSPR 13 0 O14545 O14545 TRAFD1 TRAF-type zinc finger domain-containing protein 1 1 ALPS(0.003)LNT(0.012)GS(0.194)S(0.194)S(0.596)PR;ALPSLNTGS(0.015)S(0.208)S(0.776)PR;ALPSLNTGSS(0.003)S(0.997)PR;ALPSLNTGS(0.02)S(0.223)S(0.757)PR;ALPSLNTGSS(0.003)S(0.997)PR 196.97 9.0794e-07 537236000.0 676712.0 751560.0 806733.0 900888.0 1023220.0 910050.0 793560.0 893298.0 842102.0 634737.0 True False 791265.9759287614 826169.9099129979 825968.5742719404 850414.166078303 822727.3862462299 862325.3759485366 718388.2519231305 869849.8740274684 854416.1486495334 749809.7935246733 1.0552889316225287 1.1018393158475221 1.1015708002282327 1.134173190884468 1.0972481199249062 1.1500588327807175 0.9580939834703441 1.1600940419016346 1.1395105212391679 1.0 19.516165143724066 -9.44636556387818 10.927714770113402 1.0000000096532944 1.0999032707235903 0.22419923661162622 0.05567365895824018 0.0 0.0 0.052675826361654195 0.012775764470929148 3.5779513913959444e-10 9.44636556387818 0.0999032610702959 ALPSLNTGSSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 ALPSLNTGSSSPR 13 0 O14545 O14545 TRAFD1 TRAF-type zinc finger domain-containing protein 1 1 ALPSLNTGSS(0.002)S(0.997)PR;ALPSLNTGSS(0.01)S(0.99)PR;ALPSLNTGSS(0.004)S(0.996)PR;ALPSLNTGSS(0.028)S(0.972)PR 207.08 6.621e-10 790640000.0 977598.0 784921.0 884150.0 779544.0 765000.0 912718.0 765456.0 737765.0 870860.0 590907.0 True False 963657.2732504832 783103.5636499014 811458.5999176969 836874.2662425498 720004.204047868 873683.1787895763 805087.5662750262 772044.2552435494 772774.5762376505 693044.487615915 1.3904695737000676 1.1299470346323526 1.1708607663977366 1.207533255363464 1.0389004124752437 1.2606451597285788 1.16166794579745 1.1139894610508987 1.1150432476506786 1.0 19.402588438636016 -1.5228787463551348 0.057752170842366134 0.7719869196609357 1.942681902927337 0.43847504950590777 0.07892050988757078 388.2501081448782 1.6857459333200127 7.172252758192372 38.67995241573195 0.029999999925755638 1.5228787463551348 1.1706949832664013 ALPTSKPEGSLHS(ph)SPVGPSSSK ddPTM_PC-9_AZD4547_30min_R2 2 ALPTSKPEGSLHSSPVGPSSSK 22 1 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 ALPTSKPEGSLHS(0.868)S(0.129)PVGPS(0.003)S(0.001)SK;ALPTSKPEGS(0.001)LHS(0.565)S(0.429)PVGPS(0.003)S(0.001)SK 100.01 4.7226000000000005e-05 69079000.0 33186.0 33988.0 99171.0 156148.0 122456.0 115009.0 60336.0 125930.0 72125.0 115280.0 True False 43738.457688318864 44973.956328434695 97855.9277428197 120150.49106255121 105455.09814442218 107817.46904903479 65705.7871136802 106470.41208351805 75937.38025389415 111244.08228850087 0.39317559000475516 0.40428178652954366 0.8796506360584622 1.08006186568156 0.9479614193852981 0.9691973436341585 0.5906452348923922 0.9570883223019202 0.6826195038128665 1.0 16.76336906732387 -5.2616997743747564 7.163214625144329 0.8885702476038031 0.3965091314229647 0.6630759649403848 0.13964342638510507 0.07058032336628797 27.687796416891576 0.036904145640392 0.0870147741013744 5.473942430575024e-06 5.2616997743747564 -0.4920611161808384 ALPTSKPEGSLHSS(ph)PVGPSSSK ddPTM_PC-9_AZD4547_30min_R2 1 ALPTSKPEGSLHSSPVGPSSSK 22 1 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 ALPTSKPEGSLHS(0.355)S(0.626)PVGPS(0.015)S(0.003)SK 111.66 5.2573000000000005e-06 15698000.0 14348.0 12299.0 43923.0 72197.0 52574.0 45059.0 28333.0 53910.0 34086.0 46497.0 True False 18910.36554306029 16274.4112299464 43340.55232122163 55553.09708253077 45275.00759329763 42241.45360693913 30854.58211170613 45579.44822855912 35887.7163720518 44869.154182585335 0.421455806055729 0.3627082240891192 0.9659320107719572 1.238113311796996 1.0090452654636806 0.9414363692938507 0.6876568697094237 1.0158303417774135 0.7998304631733081 1.0 15.453436367929855 -5.2628674068578 24.58969201716629 0.9594863039697545 0.39208196166648496 0.7327386137984218 0.13652081893676724 49.191685938014295 847072.887950321 0.03798240524146922 0.08664205082612735 5.459245102208409e-06 5.2628674068578 -0.5674043423032695 ALPTSKPEGSLHSS(ph)PVGPSSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALPTSKPEGSLHSSPVGPSSSK 22 1 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 ALPTSKPEGS(0.002)LHS(0.23)S(0.757)PVGPS(0.007)S(0.002)S(0.001)K;ALPTSKPEGS(0.048)LHS(0.445)S(0.482)PVGPS(0.019)S(0.003)S(0.002)K 64.843 0.009068799999999998 19551000.0 36124.7 41076.8 79367.0 96555.0 112048.0 118497.0 88159.0 89972.0 90374.0 60302.0 True False 42239.898214652145 45154.63323688614 81259.41028102378 91145.33638553372 90092.99874329794 112282.8087179536 79807.94130411214 87610.33033321402 91695.54877918948 71234.27524963058 0.5929715444795124 0.633889136636093 1.1407347094676197 1.2795151781375975 1.2647422666627772 1.57624694466918 1.1203587181091736 1.2298901059384102 1.2872391620165324 1.0 16.12028395830187 -5.30702959435518 2.984519170197392 1.2678476701612167 0.5856018587427242 0.767409920753793 0.13835021194046257 0.11191120866027848 1.9643135461727468 0.03702530109432278 0.10172626634684812 4.931401985004426e-06 5.30702959435518 -0.6822458114184925 ALPTSKPEGSLHSS(ph)PVGPSSSK ddPTM_PC-9_Lapatinib_30min_R1 2 ALPTSKPEGSLHSSPVGPSSSK 22 1 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 ALPTSKPEGSLHS(0.398)S(0.567)PVGPS(0.029)S(0.006)S(0.001)K;ALPTSKPEGSLHS(0.388)S(0.609)PVGPS(0.002)S(0.001)SK 121.62 3.5481000000000004e-07 19704800.0 57612.0 28719.0 98519.0 42964.0 74034.0 78301.0 51785.0 56395.0 92949.0 43202.0 True False 56790.44231525314 28652.502919990093 90419.14811433772 46123.71588370251 69679.46567644423 74952.24875854609 54466.173914048966 59015.31758006937 82480.104823638 50669.408136953476 1.1208033486745144 0.5654793291160167 1.7844918943980035 0.9102872439132407 1.3751782039393237 1.4792406604781911 1.0749321122290056 1.164712984619001 1.627808728310067 1.0 15.628827356567214 -5.243740873204845 24.998291005301347 1.2947966981792054 0.8431413899372112 0.2847608142059792 0.29075532906169865 1007.3036964770391 1422763.0638156037 0.06894518897087067 0.1815534580700911 5.705045688590891e-06 5.243740873204845 -0.4516553082419942 ALQAPHS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 1 ALQAPHSPSK 10 0 F2Z2Z8;Q5T173;Q96AQ6-3;Q96AQ6-2;Q96AQ6 F2Z2Z8 PBXIP1 Pre-B-cell leukemia transcription factor-interacting protein 1 1 ALQAPHS(0.652)PS(0.348)K 81.789 0.015097 0.0 28082.0 32507.0 45449.0 31863.0 35357.0 34167.0 38546.0 44403.0 31172.0 32604.0 True False 37011.49185811394 43014.25204096818 44846.316564150955 24517.47762844271 30448.29085624497 32030.53208877889 41976.51932650352 37541.536629432594 32819.68828110071 31462.543883885224 1.176366793311676 1.3671574746058477 1.4253874934480666 0.779259227064608 0.9677631589046509 1.018052837907509 1.3341743592451034 1.1932136437531031 1.043135240501344 1.0 14.941347703204896 -5.730987491461325 24.999926650424634 1.0633330430326478 1.3273893414266267 0.4160717202789801 0.14849853610080238 228.12231752780957 187278.76181487215 0.04400018704929154 0.07619943252485088 1.857857964299172e-06 5.730987491461325 0.2640562983939789 ALQAPHS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ALQAPHSPSK 10 0 F2Z2Z8;Q5T173;Q96AQ6-3;Q96AQ6-2;Q96AQ6 F2Z2Z8 PBXIP1 Pre-B-cell leukemia transcription factor-interacting protein 1 1 ALQAPHS(0.851)PS(0.149)K;ALQAPHS(0.958)PS(0.042)K;ALQAPHS(0.5)PS(0.5)K 76.868 0.012778 9837900.0 90859.0 137487.0 103030.0 98382.0 146098.0 86059.0 112184.0 71373.0 75059.0 78734.0 True False 106239.63415295002 151135.8007400716 105486.6259434511 92869.97549874763 117471.14567326837 81545.91454178885 101557.11937817505 69499.53437594436 76156.59587732289 93007.85094199896 1.1422652289773108 1.6249789583281746 1.1341690499787387 0.9985175934950126 1.2630239757558217 0.8767637754864593 1.0919198578355234 0.7472437398783172 0.8188190040517681 1.0 16.505064881114528 -6.128821625215452 0.6283124161578089 0.8651900526530536 1.4054812773598437 0.4658884291068648 0.17443616508577262 0.8324312732920156 0.6594066842314267 0.1130961007011714 0.2597918971002999 7.433243757149619e-07 6.128821625215452 0.5402912247067901 ALQAPHS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 1 ALQAPHSPSK 10 0 F2Z2Z8;Q5T173;Q96AQ6-3;Q96AQ6-2;Q96AQ6 F2Z2Z8 PBXIP1 Pre-B-cell leukemia transcription factor-interacting protein 1 1 ALQAPHS(0.958)PS(0.042)K 84.169 0.007206199999999999 3564000.0 40198.0 64155.0 32367.0 22803.0 31763.0 36755.0 43246.0 38244.0 47640.0 16053.0 True False 39624.76914858963 64006.453039171436 29705.910200233116 24480.008688578055 29894.762788460685 35183.07433008977 45485.066275696896 40020.95585658608 42274.28152855993 18827.73966072206 2.1045951273297976 3.3995824348846306 1.5777735795978107 1.3002096443710451 1.5878041298194896 1.8686828564709643 2.4158537931447315 2.1256378395796895 2.245318996881576 1.0 14.200572189060512 -5.277910887785271 24.97837221578709 1.8093582207782342 2.7520888566779487 0.3800252212655836 0.5016929425411403 758.754386134868 1150619.8241972215 0.13374616683856888 0.27969203346671845 5.2733805400425265e-06 5.277910887785271 0.9427306358997145 ALQAPHS(ph)PSKTDGK ddPTM_PC-9_Lapatinib_30min_R1 1 ALQAPHSPSKTDGK 14 1 F2Z2Z8;Q5T173;Q96AQ6-3;Q96AQ6-2;Q96AQ6 F2Z2Z8 PBXIP1 Pre-B-cell leukemia transcription factor-interacting protein 1 1 ALQAPHS(0.982)PS(0.009)KT(0.009)DGK 56.746 0.032906 4030400.0 30679.0 34586.0 21570.0 15668.0 19594.0 24042.0 21721.0 19556.0 27187.0 12394.0 True False 30241.511834160454 34505.91824195751 19796.597862607858 16820.27698691581 18441.519443286168 23013.779704639328 22845.60709833075 20464.64315268793 24124.913768198126 14536.286386033078 2.0804152471306185 2.3737780974865688 1.361874507482809 1.1571233904057685 1.2686541083151306 1.583195260018521 1.571626101167182 1.4078315884276333 1.659633907005169 1.0 13.827371127709602 -5.266268022380702 24.985617404593786 1.393508800396308 2.2270967015693213 0.7386093629786497 0.2022577704082755 179.09807096396958 926740.3526925362 0.05325743941728681 0.11691802970729134 5.416665008146419e-06 5.266268022380702 0.8335879011730132 ALQAS(ph)ALK ddPTM_PC-9_AZD4547_30min_R2 1 ALQASALK 8 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BR68 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 ALQAS(1)ALK 110.53 0.0037604 6383200.0 28530.0 44761.0 33507.0 56098.0 54659.0 64148.0 30016.0 48523.0 45963.0 39264.0 True False 37601.94653913506 59229.11790093761 33062.67528691512 43165.47280546023 47070.54133301734 60136.81541929314 32687.3658513031 41024.885297614084 48392.51034467572 37889.37931103148 0.992413896001386 1.5632116170267554 0.8726106335895804 1.1392499320487053 1.2423149227813497 1.5871681329386234 0.862705234175905 1.0827542188232602 1.2772051489000311 1.0 15.20950588592467 -10.23286792045975 0.36651296523032395 0.9356031323228858 1.1989325661313492 0.04481906731361607 0.23871477722706017 38.60613510637306 4.555501186460956 3.1316817594643593 0.18337434344256207 5.849679601133642e-11 10.23286792045975 0.2633294338084634 ALQAS(ph)ALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALQASALK 8 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BR68 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 ALQAS(1)ALK;ALQAS(1)ALK 109.83 0.0037717 9841500.0 60224.0 64584.0 52554.0 61778.0 93004.0 63081.0 77814.0 65420.0 50537.0 49489.0 True False 70418.73372178055 70995.4726992136 53807.086672154895 58316.778946978346 74780.53383480018 59772.921312246086 70442.89459542639 63702.79431821958 51276.00801838916 58460.96394529157 1.2045428089020083 1.2144081778338784 0.9203934222245834 0.9975336534230234 1.2791532808932238 1.022441596552911 1.204956091065273 1.0896637691063968 0.877098230305847 1.0 15.835185997055142 -8.161980495708109 5.891791553251942 0.9404667932202455 1.1159367645148708 0.2973687433645321 0.10996255145950051 0.2839609840624931 13.498290818701875 0.0784454204129022 0.028702642476094425 6.8868322461431804e-09 8.161980495708109 0.17546997129462527 ALQASALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALQASALK 8 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BR68 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ; 108.74 0.017458 19503400.0 143910.0 126174.0 146443.0 157446.0 172455.0 145693.0 149609.0 145495.0 144163.0 114364.0 False True 168271.12064793898 138699.72086508342 149934.75650817002 148624.8110668191 138663.68072857626 138052.60260213158 135436.952444639 141675.9104146949 146271.1111453989 135097.28789507385 1.2455551348938276 1.0266654721655661 1.1098280272259795 1.1001317153180135 1.0263987004407693 1.0218754554817786 1.0025142218238234 1.0486954447577843 1.0827094564548434 1.0 17.04363918700121 ALQASALK ddPTM_PC-9_Lapatinib_30min_R1 1 ALQASALK 8 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BR68 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 111.17 0.017279 26472000.0 250630.0 205990.0 230380.0 224940.0 200810.0 194350.0 203170.0 170110.0 243250.0 184120.0 False True 247055.9702400872 205513.0428109882 211439.04569251765 241482.83797784284 188998.75060765014 186038.10355197775 213689.14848155505 178013.93161708672 215852.62346394215 215944.89667552148 1.1440695012640802 0.9516920565147313 0.9791342557644495 1.1182613791549547 0.8752174907455184 0.8615072938330113 0.9895540564806404 0.8243488702794872 0.9995727001980603 1.0 17.720303696849243 -6.273705952225327 24.99139240908563 0.9163005713081768 1.0364498521225245 0.36675673804063436 0.07822738524320651 825.4775572051582 1681789.4591314336 0.023342776204073563 0.026650639442438142 5.324686558109971e-07 6.273705952225327 0.12014928081434773 ALQCLFYLADK ddPTM_PC-9_AZD4547_30min_R2 1 ALQCLFYLADK 11 0 H0YFL5;E7ES84;P50748-2;P50748 H0YFL5 KNTC1 Kinetochore-associated protein 1 0 87.639 0.042661000000000004 0.0 27032.0 38022.0 34325.0 39010.0 36924.0 30050.0 31343.0 42034.0 31637.0 33243.0 False True 35627.61369947071 50311.86793926516 33869.82807244342 30016.84719849199 31797.739954633875 28170.968749606516 34132.46628056347 35538.61114522828 33309.26723178438 32079.172688381717 1.1106151036237337 1.568365507053331 1.0558198742048681 0.9357113878863637 0.9912269329236857 0.878170052054034 1.0640070619067246 1.1078406382375154 1.0383455818936433 1.0 14.969349315177707 -5.423558762136569 7.487824958382615 1.0030422032936215 1.3376218816721375 0.5567974007687193 0.11878747003744668 0.17804342141438506 11.815057371501984 0.02976365608257796 0.06224785443319673 3.7708671990885733e-06 5.423558762136569 0.334579678378516 ALQEGEGDLS(ph)ISADRLSEK ddPTM_PC-9_Lapatinib_30min_R1 1 ALQEGEGDLSISADRLSEK 19 1 P49589-3;B4DKY1;P49589-2;P49589 P49589-3 CARS Cysteine--tRNA ligase, cytoplasmic 1 ALQEGEGDLS(0.446)IS(0.361)ADRLS(0.193)EK 46.22 0.041277 3775100.0 14546.0 13264.0 12072.0 8125.7 13455.0 20012.0 13921.0 12266.0 12436.0 11019.0 True False 14338.571372590293 13233.288022937732 11079.48675926759 8723.291084540575 12663.603353547796 19156.13341025049 14641.76126402386 12835.923139234526 11035.326723114416 12923.61946810542 1.1094857294411116 1.0239614417305114 0.857305245377348 0.6749882342225443 0.9798805500889805 1.482257618117469 1.1329458670737476 0.993214259435035 0.853888243177449 1.0 13.657722556190807 -6.533233545588269 24.99910323996307 1.1097342129683712 0.908334786294579 0.1664806644219038 0.184736022037709 373.4661296784956 901635.0563113566 0.06576970171775862 0.06583295003926778 2.929317555939276e-07 6.533233545588269 -0.20139942667379218 ALQESATGQPEPTS(ph)SPDNKPFK ddPTM_PC-9_AZD4547_30min_R2 1 ALQESATGQPEPTSSPDNKPFK 22 1 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 ALQESATGQPEPT(0.104)S(0.448)S(0.448)PDNKPFK 91.50299999999999 9.3445e-05 5468800.0 34227.0 25884.0 41399.0 50969.0 50752.0 44253.0 41841.0 48862.0 47932.0 48835.0 True False 45110.47403417373 34250.49681079218 40850.02221037396 39218.88451320013 43705.96084328836 41485.85291435398 45564.76794324271 41311.50063705911 50465.587664882594 47125.30151421711 0.9572453137634453 0.7267963431588705 0.8668384264459299 0.8322256463731756 0.927441511012992 0.8803307688511705 0.96688544113604 0.8766310094503257 1.0708809502185945 1.0 15.524214228523308 -7.386418586914017 0.6101691815006781 1.0165877277263862 0.8352441681019324 0.43262204769529355 0.06871529655886083 0.7166659554842498 0.5396745152723419 0.05943016725673693 0.04023181018321585 4.1075363276329526e-08 7.386418586914017 -0.1813435596244538 ALQEVGSGGTLGLSS(ph)PKS ddPTM_PC-9_AZD4547_30min_R2 3 ALQEVGSGGTLGLSSPKS 18 1 A0A0M3HER3 A0A0M3HER3 1 ALQEVGSGGTLGLS(0.008)S(0.991)PKS(0.001);ALQEVGSGGTLGLS(0.309)S(0.691)PKS;ALQEVGSGGTLGLS(0.026)S(0.973)PKS(0.001) 198.98 1.8499e-54 6302900.0 65506.0 55644.0 64524.0 91044.0 85248.0 77256.0 62638.0 80553.0 73894.0 77994.0 True False 86335.54539055662 73629.83482227314 63668.369600767335 70055.21241577802 73412.78668759155 72425.1701071414 68212.66065411532 68105.38477379181 77799.88598240913 75263.45379952592 1.1471111280718351 0.9782946583662752 0.845940046418231 0.9307998620735539 0.975410813369476 0.9622886866188116 0.9063185013513821 0.9048931630908068 1.0337007146873614 1.0 16.199661874975945 -4.789042140266903 4.042902188932719 0.9397873266140703 1.1634258947153124 0.5847490367486918 0.0506098728661569 0.14692359498763527 4.538335877086168 0.01260221623305314 0.0940263720410143 1.6253910338866075e-05 4.789042140266903 0.22363856810124216 ALQEVGSGGTLGLSS(ph)PKS ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALQEVGSGGTLGLSSPKS 18 1 A0A0M3HER3 A0A0M3HER3 1 ALQEVGSGGTLGLS(0.114)S(0.886)PKS;ALQEVGSGGTLGLS(0.003)S(0.997)PKS 276.3 1.9220999999999994e-91 11244800.0 48238.0 43100.0 40878.0 63818.0 60901.0 61930.0 65227.0 75348.0 66684.0 53955.0 True False 56403.74065607159 47378.68316202314 41852.686550678314 60242.484360747556 48967.88623148648 58682.281778465825 59048.226357414766 73370.19483780499 67659.12734626647 63736.614392455034 0.8849503726189214 0.7433511116591675 0.6566506073412133 0.9451786062844106 0.768285022639721 0.9206997004442783 0.9264412131122661 1.1511467237031396 1.061542537067607 1.0 15.959834766582697 -7.243797031789625 1.3841735991188284 1.077590471062098 0.7925867804066391 0.6278367926563259 0.08699032005285116 0.26660005925872077 0.9986894649437039 0.05219744498423574 0.030997120682355453 5.70430801728354e-08 7.243797031789625 -0.28500369065545894 ALQEVGSGGTLGLSS(ph)PKS ddPTM_PC-9_Lapatinib_30min_R1 4 ALQEVGSGGTLGLSSPKS 18 1 A0A0M3HER3 A0A0M3HER3 1 ALQEVGSGGTLGLS(0.036)S(0.964)PKS;ALQEVGSGGTLGLS(0.103)S(0.897)PKS;ALQEVGSGGTLGLS(0.079)S(0.921)PKS;ALQEVGSGGTLGLS(0.063)S(0.937)PKS 260.96 3.0693999999999986e-152 7258400.0 101363.0 80346.0 81983.0 83365.0 86809.0 87215.0 80175.0 74431.0 85274.0 76738.0 True False 99917.54503230215 80159.96377344367 75242.67420353186 89495.94019748757 81703.06529306054 83485.01775809497 84326.0692007121 77889.33598372458 75669.5441449709 90002.06105304233 1.1101695212670315 0.8906458678340904 0.836010568237853 0.9943765637182855 0.9077910476395556 0.9275900660640808 0.9369348680916861 0.8654172479208097 0.8407534589721827 1.0 16.457670419180168 -4.758385359772043 24.988601389897575 0.908333723905355 1.1101697982895062 0.5516291177057441 0.05380299701783826 63.566546916452225 520022.39700919826 0.013203804812340104 0.09109427312637158 1.744273730684081e-05 4.758385359772043 0.2018360743841512 ALQLEEER ddPTM_PC-9_AZD4547_30min_R2 2 ALQLEEER 8 0 P15311;E7EQR4 P15311 EZR Ezrin 0 ; 124.08 0.015285 47716000.0 75446.0 75630.0 107305.0 126979.0 120847.0 94062.0 90801.0 112761.0 77563.0 98204.0 False True 99436.25862571296 100075.91847474153 105882.06558815844 97705.95335599371 104069.4800210605 88180.28827039893 98882.11309515497 95336.37844000306 81662.82183199708 94765.90785097107 1.0492830267830757 1.0560329209542423 1.117301231943756 1.0310242952523196 1.0981742525457598 0.9305064476253561 1.0434355068982935 1.0060197870939949 0.8617320688830427 1.0 16.53208052073647 -7.032414249550269 0.8978687527615316 0.954503514839941 1.0733275949113765 0.40825237624764654 0.05550053057799255 0.5901985882713182 0.9800948433136442 0.038147561140063485 0.027044161502508598 9.280807194478468e-08 7.032414249550269 0.11882408007143552 ALQLEEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALQLEEER 8 0 P15311;E7EQR4 P15311 EZR Ezrin 0 ; 112.41 0.017187 29525000.0 87149.0 107232.0 127928.0 125824.0 127899.0 132047.0 125178.0 134225.0 108524.0 106471.0 False True 101901.60442879034 117877.28428840043 130978.28868964153 118774.4892069119 102838.10908065356 125122.22286454191 113320.23362976185 130701.73597314334 110110.95819276311 125773.34947602793 0.8102002916620465 0.9372198862436079 1.0413834825525232 0.9443533920478917 0.8176462621777775 0.9948230160507086 0.9009876424684101 1.0391846644591012 0.8754713033523049 1.0 16.94046673169391 ALQLEEER ddPTM_PC-9_Lapatinib_30min_R1 1 ALQLEEER 8 0 P15311;E7EQR4 P15311 EZR Ezrin 0 108.74 0.017458 28346000.0 35908.0 31817.0 29458.0 35038.0 28003.0 29430.0 26531.0 29939.0 34160.0 23304.0 False True 35395.94533527926 31743.329691330644 27036.076951168383 37614.811403341606 26355.91859601625 28171.34750468077 27904.645362819992 31330.075237692996 30312.541079252856 27332.06534937186 1.2950336859959515 1.1613952068960702 0.98917065379363 1.3762154788718175 0.9642856571255035 1.0307068691875565 1.0209490210903982 1.1462754401182864 1.1090468536417974 1.0 14.73830686087834 -1.5228787452819517 0.6141374912867912 1.0708827979560707 15.712340670740838 0.25720036327486984 0.11277227179283872 275.75587254898625 2.0319465571167554 0.04978065542693875 5439.922349657816 0.0299999999998885 1.5228787452819517 14.641457872784768 ALQLS(ph)NSPGASSAFLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALQLSNSPGASSAFLK 16 0 Q12802-2;Q12802;Q12802-4;H0YMW2 Q12802-2 AKAP13 A-kinase anchor protein 13 1 ALQLS(0.548)NS(0.241)PGAS(0.171)S(0.04)AFLK 127.2 2.5427e-05 45990000.0 41720.0 39987.0 52258.0 50364.0 58000.0 47339.0 56011.0 51981.0 41297.0 36889.0 True False 48782.371992439694 43956.64509512341 53504.02890956863 47542.268362291084 46635.31635648376 44856.45950445333 50705.23259547665 50616.553828422075 41900.890498751745 43576.68368683665 1.1194604055465456 1.0087193741271672 1.2278132336566667 1.0910024430485132 1.070189661325032 1.0293683619160598 1.1635863105111264 1.1615513055600415 0.9615438109029137 1.0 15.411268786865943 -8.271508337529365 24.93577849017681 0.9807718825999325 1.1068584226759624 0.4025471228146853 0.06242569797738264 772.3439833974655 1912687.483311191 0.057727509977583503 0.015652307595959505 5.351698795504464e-09 8.271508337529365 0.12608654007602982 ALQLSNS(ph)PGASSAFLK ddPTM_PC-9_AZD4547_30min_R2 1 ALQLSNSPGASSAFLK 16 0 Q12802-2;Q12802;Q12802-4;H0YMW2 Q12802-2 AKAP13 A-kinase anchor protein 13 1 ALQLS(0.343)NS(0.529)PGAS(0.108)S(0.021)AFLK 124.04 3.6776e-05 60035000.0 27331.0 25094.0 34047.0 44130.0 33206.0 28605.0 29055.0 33887.0 23263.0 32802.0 True False 36021.68947988435 33205.14476008415 33595.51453408538 33956.51030170344 28595.920077282324 26816.32482803643 31640.838713006804 28650.542795792688 24492.63468764424 31653.611964151747 1.1379961794148334 1.0490159795251657 1.0613485302130092 1.0727530981348912 0.9034014857346355 0.8471805637349183 0.999596467816709 0.9051271250889129 0.7737706115618832 1.0 14.950082513182505 -6.259234662686035 6.900854715962446 0.9016984454204475 1.077118761741542 0.6299365116794662 0.0658366188563064 0.0908908782990595 28.59400357903168 0.019853713380816127 0.024173224128819684 5.505101584323507e-07 6.259234662686035 0.17542031632109456 ALQLSNS(ph)PGASSAFLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALQLSNSPGASSAFLK 16 0 Q12802-2;Q12802;Q12802-4;H0YMW2 Q12802-2 AKAP13 A-kinase anchor protein 13 1 ALQLS(0.007)NS(0.731)PGAS(0.222)S(0.04)AFLK 85.28 0.004767 42896000.0 53799.0 49307.0 64225.0 59808.0 71965.0 66187.0 64654.0 60706.0 54866.0 43923.0 True False 62906.108121315054 54201.87310138923 65756.36757466881 56457.15166015219 57863.97485507503 62716.037204445565 58529.50506557549 59112.53182332377 55668.3114537258 51885.892205723314 1.2123933008976213 1.04463604261604 1.2673265271020144 1.088102165349768 1.1152159555366055 1.2087300523961622 1.1280427603231875 1.1392794709773404 1.0728987994078527 1.0 15.663054702109143 -8.502219102682789 1.663111282088779 1.0000475869821996 1.1508826026432302 0.3854463450997936 0.06137888599157015 0.3857319986648204 2.3740581785510018 0.05465892681586504 0.01582305581897465 3.1461606675028548e-09 8.502219102682789 0.15083501566103052 ALQLSNS(ph)PGASSAFLK ddPTM_PC-9_Lapatinib_30min_R1 1 ALQLSNSPGASSAFLK 16 0 Q12802-2;Q12802;Q12802-4;H0YMW2 Q12802-2 AKAP13 A-kinase anchor protein 13 1 ALQLS(0.333)NS(0.665)PGAS(0.001)SAFLK 136.26 9.8822e-06 41694000.0 64987.0 63148.0 72091.0 59075.0 64201.0 64755.0 61733.0 56541.0 70212.0 42286.0 True False 64060.27346284378 63001.78468580156 66163.95625930745 63419.57256842296 60424.82340402242 61985.57960127771 64929.232678111155 59168.10127306855 62303.985194862515 49595.078757446754 1.2916659287132408 1.270323311591511 1.3340830968914 1.2787472902016603 1.2183632916390836 1.249833272862189 1.3091870061474993 1.1930236377371293 1.256253377468576 1.0 15.59790935087796 -13.858192585200781 0.2251842685714795 8.637867356103604e-12 1.300078805477059 0.8433071935483912 0.035264443354425995 41.55778202406037 0.5451988575031259 18.87694746192348 0.065018200896074 1.3861410169075523e-14 13.858192585200781 1.3000788054684211 ALQLSNSPGAS(ph)SAFLK ddPTM_PC-9_AZD4547_30min_R2 1 ALQLSNSPGASSAFLK 16 0 Q12802-2;Q12802;Q12802-4;H0YMW2 Q12802-2 AKAP13 A-kinase anchor protein 13 1 ALQLSNS(0.018)PGAS(0.491)S(0.491)AFLK 151.73 3.1198e-05 49755000.0 59411.0 55197.0 78890.0 94003.0 85990.0 71892.0 58192.0 86657.0 53551.0 81335.0 True False 78302.46217443237 73038.35081383464 77843.86705418967 72332.06068187232 74051.77279544398 67396.58187509871 63370.97526715858 73266.15182975805 56381.596533466756 78487.48640644709 0.9976426276278415 0.9305731927202493 0.991799720162722 0.9215744317164276 0.9434850851506087 0.8586920662242363 0.8074022773387375 0.933475579156015 0.7183514100769506 1.0 16.26017503688565 -6.721403576424603 3.8005638274888347 0.8550695126777861 0.9575687943388008 0.29028935141883516 0.07275758813601081 0.26798236363805356 8.10760812220427 0.02374783749639342 0.022773806576829272 1.899312487274006e-07 6.721403576424603 0.10249928166101474 ALQS(ph)PALGLR ddPTM_PC-9_Lapatinib_30min_R1 2 ALQSPALGLR 10 0 P46940;A0A0J9YXZ5 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 1 ALQS(1)PALGLR;ALQS(1)PALGLR 130.69 0.00020482 14361600.0 67006.0 111776.0 114306.0 106319.0 105340.0 113613.0 114050.0 111518.0 118635.0 91270.0 True False 66050.48215260459 111517.1895394972 104908.20191391991 114138.05392978695 99144.10830640835 108754.03683483863 119954.95094906425 116699.53339647435 105273.07701806696 107045.89789036926 0.6170295495138916 1.0417698551485568 0.9800300990642475 1.066253412593924 0.9261831631133264 1.0159570705476144 1.1205936267816237 1.0901822087194022 0.9834386846461138 1.0 16.707869985651932 -4.760210209393908 24.999840186096353 1.0272632713208458 0.6170290572080642 0.8347266562905844 0.05444254168008245 12.176230784995527 247549.29841206849 0.014129116987053715 0.08499587877813822 1.736959893207347e-05 4.760210209393908 -0.4102342141127816 ALQT(ph)SPQPPEGPGLPR ddPTM_PC-9_Lapatinib_30min_R1 1 ALQTSPQPPEGPGLPR 16 0 A0A2R8YGT1;F8W9A8;B7WPL9;Q6PFW1-7;Q6PFW1-4;Q6PFW1-3;Q6PFW1-2;Q6PFW1;H7C398;Q6PFW1-5 A0A2R8YGT1 PPIP5K1 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 1 ALQT(0.966)S(0.034)PQPPEGPGLPR 218.12 8.390500000000001e-22 10151000.0 35186.0 32465.0 33735.0 27867.0 33960.0 28300.0 24536.0 21818.0 30873.0 20784.0 True False 34684.24118767786 32389.82928714367 30961.43852086584 29916.43214158687 31962.539567928856 27089.67497052213 25806.354024429966 22831.743930524925 27395.75763289736 24376.4867070608 1.42285644377257 1.328732465690462 1.2701353928865255 1.2272659510413118 1.3112037001899337 1.1113034989851691 1.0586576455644445 0.9366298025183246 1.1238599705576935 1.0 14.573202590185874 -6.892064874070575 1.701757908209115 1.0183421566287403 1.3154159477764946 0.8102611117419508 0.06503125740670612 0.1560689975126168 0.9273824785728846 0.029673094398052872 0.024448920914044405 1.282139044897393e-07 6.892064874070575 0.29707379114775434 ALQTS(ph)PQPPEGPGLPR ddPTM_PC-9_AZD4547_30min_R2 1 ALQTSPQPPEGPGLPR 16 0 A0A2R8YGT1;F8W9A8;B7WPL9;Q6PFW1-7;Q6PFW1-4;Q6PFW1-3;Q6PFW1-2;Q6PFW1;H7C398;Q6PFW1-5 A0A2R8YGT1 PPIP5K1 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 1 ALQT(0.062)S(0.938)PQPPEGPGLPR 67.648 0.024612000000000002 8425700.0 9491.2 13987.0 19617.0 23193.0 21851.0 23938.0 15632.0 26066.0 17844.0 17506.0 True False 12509.204170775989 18508.0242193073 19356.865762479898 17846.212178278005 18817.365825715107 22441.153075809692 17023.217716803374 22038.098637091873 18787.197410752 16893.12026841171 0.7404910384830939 1.0955953622087973 1.1458431275526477 1.0564189382851001 1.1139070536839502 1.3284196595564526 1.0077012089137216 1.3045605718145932 1.1121212133842442 1.0 14.044148207392793 -4.753982824801296 3.626489318802888 1.1427539838574199 0.6817075842330189 0.5574434360597142 0.10418014917526154 0.21599456113106605 4.653195417488469 0.02493735998493944 0.28264673925915457 1.7620457292843665e-05 4.753982824801296 -0.46104639962440097 ALQTS(ph)PQPPEGPGLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALQTSPQPPEGPGLPR 16 0 A0A2R8YGT1;F8W9A8;B7WPL9;Q6PFW1-7;Q6PFW1-4;Q6PFW1-3;Q6PFW1-2;Q6PFW1;H7C398;Q6PFW1-5 A0A2R8YGT1 PPIP5K1 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 1 ALQT(0.212)S(0.788)PQPPEGPGLPR 98.508 0.012275 0.0 5185.0 5429.0 6941.3 8289.3 10461.0 6953.4 9141.6 9467.0 8764.0 5724.4 True False 6062.71809158197 5967.955240988947 7106.806917026847 7824.877395273194 8411.242144916832 6588.751463238886 8275.64146854742 9218.501281115638 8892.156920140933 6762.188405674535 0.8965615460365465 0.8825479094875407 1.0509625716821382 1.157151638766364 1.2438639150986215 0.9743519505771078 1.2238111351057388 1.3632423008770167 1.3149821310330574 1.0 12.723274497306528 -5.512224613245312 1.8086426011314345 1.1979068001571405 0.875536639939672 0.5037121132201394 0.11586790245126816 0.3135703711972614 1.979719184572026 0.036424277410749446 0.10312452848647903 3.074506296150056e-06 5.512224613245312 -0.32237016021746845 ALS(ph)EGEEITAAPER ddPTM_PC-9_Lapatinib_30min_R1 1 ALSEGEEITAAPER 14 0 O43822-2;O43822-3;O43822;O43822-4 O43822-2 C21orf2 Protein C21orf2 1 ALS(1)EGEEITAAPER 113.53 0.00020042 1043300.0 3878.1 3037.0 3888.8 2513.5 3742.4 3250.4 3875.9 3572.0 2619.1 2847.8 True False 3822.797582843559 3029.9680130927227 3569.0778752021065 2698.351174790201 3522.279389841489 3111.387969052476 4076.5751370756475 3737.968160227108 2324.1093776543084 3340.038435545025 1.1445370035748579 0.9071656124814308 1.0685738934078184 0.8078802764884608 1.0545625320825764 0.9315425642833244 1.2205174328811084 1.119139265119609 0.6958331236314237 1.0 11.705648989292897 -7.018156815792808 0.0072441066821179595 0.4719502730458668 1.5237523947798355 0.009138663816989578 0.1522283974268388 57686.362354814555 200.14646266387652 14301.895956640416 14749.313096982389 9.590542720341373e-08 7.018156815792808 1.0518021217339686 ALS(ph)GHSAADR ddPTM_PC-9_AZD4547_30min_R2 1 ALSGHSAADR 10 0 A0A0U1RQE4 A0A0U1RQE4 1 ALS(0.997)GHS(0.003)AADR 94.76700000000001 0.0061754 3968200.0 16212.0 18827.0 23850.0 26837.0 24246.0 21695.0 23483.0 25402.0 22470.0 22567.0 True False 21367.078769451735 24912.4595679487 23533.733416686835 20650.144277516763 20879.861416424366 20338.408220389796 25572.94150740108 21476.704579889803 23657.718326585822 21776.936198860203 0.9811792886903016 1.1439836779818737 1.0806723774999434 0.948257555100776 0.9588061987120673 0.9339425911278695 1.1743131023518156 0.9862133214595121 1.0863657821536925 1.0 14.410513374851718 -10.70629304615487 14.818199214624556 0.9999999999999738 1.0325703091019827 0.014582562456498804 0.08048536426727142 0.0 0.0 0.07964146900492226 0.019315893320005946 1.9665588793520747e-11 10.70629304615487 0.032570309102008865 ALS(ph)GHSAADR ddPTM_PC-9_Lapatinib_30min_R1 1 ALSGHSAADR 10 0 A0A0U1RQE4 A0A0U1RQE4 1 ALS(0.968)GHS(0.032)AADR 92.611 0.007321899999999999 4163400.0 23084.0 24546.0 21489.0 19223.0 26295.0 26601.0 24654.0 29269.0 27577.0 20691.0 True False 22754.817926912852 24489.165245101754 19722.25736993882 20636.723546048168 24748.379797959056 25463.337239959666 25930.463487051526 30628.94459173775 24470.987861316065 24267.41178097551 0.9376697495507758 1.0091379116210526 0.8127054317922822 0.850388320448181 1.0198195020270189 1.049281129350667 1.0685302462860817 1.262143028196743 1.0083888666075278 1.0 14.566732626898485 -6.591512056813174 2.302142639573122 1.098058705593063 0.9049409082857452 0.47725105513338417 0.08484437236683902 0.25283830732760043 2.7210200007238434 0.03168507944146231 0.03257696752938512 2.5614621522028125e-07 6.591512056813174 -0.19311779730731782 ALS(ph)HDSIFIPESGQDATRPVR ddPTM_PC-9_AZD4547_30min_R2 2 ALSHDSIFIPESGQDATRPVR 21 1 Q6NV74;C9JFM2;C9JXD6;C9JK00 Q6NV74 KIAA1211L Uncharacterized protein KIAA1211-like 1 ALS(0.999)HDS(0.001)IFIPESGQDATRPVR;ALS(0.987)HDS(0.013)IFIPESGQDATRPVR 110.57 1.6143e-05 5825400.0 3891.6 1459.1599999999999 9479.400000000001 26212.0 17595.0 11538.8 6157.599999999999 17109.2 5359.9 13151.9 True False 5129.047849691484 1930.8049345709903 9353.69696227007 20169.22837136304 15152.23796180758 10817.277011912134 6705.614471148193 14465.366270303542 5643.213371547278 12691.455984126804 0.4041339193947787 0.1521342340063935 0.7370073988334147 1.5891973621142192 1.1938928032180447 0.8523275048537612 0.5283565951404552 1.1397720079079474 0.4446466487852333 1.0 13.631569966505145 -5.43123215350394 5.0600163334288935 0.9703879269904894 0.29359699913446546 0.4253223616274596 0.3140727005592676 0.21093424521783746 8.70708936372139 0.08718793176232753 0.18557437491613207 3.7048262616855008e-06 5.43123215350394 -0.6767909278560239 ALS(ph)IESLSPTDSSNGVNWR ddPTM_PC-9_AZD4547_30min_R2 3 ALSIESLSPTDSSNGVNWR 19 0 H3BRG5;Q9Y3M8-5;Q9Y3M8-3;Q9Y3M8-4;Q9Y3M8-2;Q9Y3M8 H3BRG5 STARD13 StAR-related lipid transfer protein 13 1 ALS(0.988)IES(0.001)LS(0.008)PT(0.002)DSSNGVNWR;ALS(0.945)IES(0.002)LS(0.001)PT(0.002)DS(0.025)S(0.025)NGVNWR;ALS(0.944)IES(0.056)LSPTDSSNGVNWR 168.55 6.281200000000001e-08 38226400.0 15054.0 17937.5 23874.9 26864.8 22983.5 20802.4 17786.1 25305.1 17833.1 21164.7 True False 19840.858857348027 23735.446088069242 23558.303226417454 20671.535417022485 19792.637749088077 19501.62263949466 19369.028443758732 21394.778248349325 18775.72125900479 20423.730295033314 0.9714610686066966 1.162150388063109 1.1534770037649005 1.0121331959641786 0.9691000352614964 0.9548511637091637 0.9483590002394878 1.0475450830621353 0.9193091069935794 1.0 14.317958771066193 -5.930890048817367 5.375077369445691 0.9747142545765257 1.1015851951683813 0.4707856646796731 0.057890495294227275 0.16598384518542048 8.93608490419944 0.016203771927523557 0.024274504370057744 1.1724921701091095e-06 5.930890048817367 0.12687094059185555 ALS(ph)IESLSPTDSSNGVNWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ALSIESLSPTDSSNGVNWR 19 0 H3BRG5;Q9Y3M8-5;Q9Y3M8-3;Q9Y3M8-4;Q9Y3M8-2;Q9Y3M8 H3BRG5 STARD13 StAR-related lipid transfer protein 13 1 ALS(0.997)IES(0.003)LSPTDSSNGVNWR;ALS(0.901)IES(0.088)LS(0.01)PT(0.001)DSSNGVNWR;ALS(0.999)IES(0.001)LSPTDSSNGVNWR;ALS(1)IESLSPTDSSNGVNWR 258.92 9.8907e-66 36785800.0 29880.199999999997 32531.7 48314.2 49523.0 53897.0 44077.3 49299.8 39988.8 42232.0 31870.6 True False 34938.327699149006 35761.23218148465 49466.19376062383 46748.38686573225 43336.26975285181 41765.80879434797 44629.76604435703 38939.13637163591 42849.56310490551 37648.48749246922 0.9280141122837319 0.9498716831224077 1.3138959107060673 1.241706904562455 1.1510759831061026 1.1093621968930978 1.1854331745275097 1.034281559901307 1.1381483283618408 1.0 15.200304286121408 -5.135166863649508 8.449769345730997 1.151409494856519 0.9339547315539588 0.4815295282124804 0.0862410604616173 0.23898352760114716 15.146871189645896 0.022478745136043247 0.06002060410831463 7.3254302302828344e-06 5.135166863649508 -0.2174547633025602 ALS(ph)IESLSPTDSSNGVNWR ddPTM_PC-9_Lapatinib_30min_R1 4 ALSIESLSPTDSSNGVNWR 19 0 H3BRG5;Q9Y3M8-5;Q9Y3M8-3;Q9Y3M8-4;Q9Y3M8-2;Q9Y3M8 H3BRG5 STARD13 StAR-related lipid transfer protein 13 1 ALS(0.995)IES(0.005)LSPTDSSNGVNWR;ALS(1)IESLSPTDSSNGVNWR;ALS(0.986)IES(0.014)LSPTDSSNGVNWR;ALS(0.997)IES(0.003)LSPTDSSNGVNWR 289.59 2.1486999999999996e-106 34595900.0 48348.8 39206.5 53311.1 47277.9 47375.9 45122.4 38062.7 31535.8 49604.8 34874.600000000006 True False 47659.337245915995 39115.71975809017 48928.06714479708 50754.87448045102 44589.34270660311 43192.62013745184 40033.40036377854 33001.06839509799 44017.78506229868 40902.628142516485 1.1651900968284286 0.9563131156707042 1.1962083945881832 1.2408707407163786 1.0901339285886729 1.0559864267634922 0.9787488526236187 0.8068202434355269 1.0761603119713505 1.0 15.319905924094478 -7.052504747861272 2.2109108821780388 0.9481982500014765 1.1304302334492964 0.40210021363168214 0.09421388452302168 0.3132715814956318 3.0406385631983732 0.04220943977320001 0.031979753172980206 8.861255361679744e-08 7.052504747861272 0.18223198344781988 ALS(ph)ISPLSDASLDLQR ddPTM_PC-9_AZD4547_30min_R2 2 ALSISPLSDASLDLQR 16 0 P10070 P10070 GLI2 Zinc finger protein GLI2 1 ALS(0.645)IS(0.292)PLS(0.002)DAS(0.06)LDLQR;ALS(0.969)IS(0.03)PLSDASLDLQR 99.238 0.0019408000000000001 4035800.0 19331.7 19682.6 23025.7 28775.6 26148.5 23382.2 19229.1 24764.0 25241.0 23564.2 True False 25478.77847566061 26044.61553577879 22720.3641732749 22141.829998588197 22518.2321309648 21920.107337672194 20940.452648297334 20937.2928201083 26575.1877294772 22739.224530384272 1.1204770172182315 1.1453607620162172 0.9991705804617843 0.9737284562629727 0.9902814452126905 0.9639777868582295 0.9208956365383785 0.9207566771739195 1.1686936682456912 1.0 14.47289543478026 -5.296588904035308 5.461646841856417 0.9843772816634223 1.1335560725119396 0.4193706004673413 0.06580843030665114 0.1546037255383943 13.107230245086859 0.017112894227216166 0.03827177926403898 5.051392277553728e-06 5.296588904035308 0.14917879084851726 ALS(ph)ISPLSDASLDLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALSISPLSDASLDLQR 16 0 P10070 P10070 GLI2 Zinc finger protein GLI2 1 ALS(0.998)IS(0.002)PLSDASLDLQR;ALS(0.98)IS(0.019)PLSDASLDLQR 127.03 0.00014991 1355000.0 8042.2 7900.1 9438.6 8936.8 9980.1 7714.799999999999 8474.4 8667.8 8172.5 6271.7 True False 9403.58561930965 8684.369718057987 9663.652020089834 8436.100069496519 8024.5710477472985 7310.222306870785 7671.643482657108 8440.279434293238 8292.007351648997 7408.709563250121 1.2692609339087653 1.1721838525207684 1.3043637272575839 1.138673340812633 1.0831266874803775 0.9867065572568983 1.035489840324047 1.1392374558938139 1.1192242428803463 1.0 12.855006562844382 -6.016126058561528 3.3097358372937373 1.0635362087995694 1.2407816417516242 0.6978032141684659 0.055012851851138016 0.14759440869636567 3.3599301128568073 0.017264507806023996 0.02495782107891483 9.635493026653233e-07 6.016126058561528 0.17724543295205475 ALS(ph)LGTIPSLTR ddPTM_PC-9_AZD4547_30min_R2 2 ALSLGTIPSLTR 12 0 Q5SNT2;H0Y4R5;H0Y994 Q5SNT2 TMEM201 Transmembrane protein 201 1 ALS(0.996)LGT(0.002)IPS(0.002)LTR;ALS(0.974)LGT(0.025)IPS(0.001)LTR 113.95 0.00079137 23534000.0 66809.0 62376.0 98836.0 124854.0 108861.0 64645.0 96685.0 95261.0 75394.0 77203.0 True False 88052.87228647304 82537.82217083791 97525.37006170479 96070.83927507095 93747.5292276403 60602.73793072591 105289.77769633643 80540.60133000884 79379.17292009835 74500.14646876436 1.181915425138002 1.1078880523468972 1.3090627963073094 1.2895389315153967 1.258353623062282 0.8134579702623107 1.4132828281147236 1.0810797716186646 1.065490159182165 1.0 16.184955641494078 ALS(ph)LGTIPSLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALSLGTIPSLTR 12 0 Q5SNT2;H0Y4R5;H0Y994 Q5SNT2 TMEM201 Transmembrane protein 201 1 ALS(0.997)LGT(0.003)IPSLTR;ALS(0.999)LGT(0.001)IPSLTR 169.09 6.1897e-05 16478200.0 91790.0 83499.0 81693.0 74833.0 116216.0 73412.0 70176.0 68409.0 67472.0 57816.0 True False 107328.23406486178 91788.22889433347 83640.87094242767 70640.34962185951 93444.30906353654 69562.14548556005 63528.42124975754 66613.33623532693 68458.65035551685 68297.58312879578 1.5714792405239564 1.3439454910320758 1.2246534520071886 1.034302333783111 1.3681934965007325 1.0185154773980734 0.9301708543617928 0.9753395828034984 1.0023583151751845 1.0 16.059546905798424 -1.522878745280339 0.3353797360802566 0.9621472170458811 7.413527871907487 0.7518200551984336 0.10235657821353669 29.93519090298361 0.4251910820050664 0.09492794452782909 120.36632725852895 0.029999999999999905 1.522878745280339 6.451380654861605 ALS(ph)PAELR ddPTM_PC-9_AZD4547_30min_R2 1 ALSPAELR 8 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 ALS(1)PAELR 94.40899999999999 0.0067423000000000005 7285100.0 25885.0 32597.0 34168.0 32382.0 31714.0 30111.0 26202.0 40212.0 34036.0 30009.0 True False 34115.89155855281 43133.34278092228 33714.90999502541 24916.83019691278 27311.05852348767 28228.154409963452 28533.92724000015 33998.15937983342 35835.07347412882 28958.3940440287 1.178100260210652 1.4894936064251978 1.1642534438810674 0.8604354978742579 0.94311371279649 0.9747831446400314 0.985342184259832 1.1740346970948112 1.2374675688038752 1.0 14.821693976136341 -5.519633143176204 24.13147857067399 1.0241343207328717 1.3320661326518548 0.49744079231087146 0.1242395163905161 64.70651508465254 481099.8641213904 0.035317018449626446 0.06286994153570408 3.0225038089087424e-06 5.519633143176204 0.3079318119189831 ALS(ph)PELGTK ddPTM_PC-9_Lapatinib_30min_R1 2 ALSPELGTK 9 0 Q15583 Q15583 TGIF1 Homeobox protein TGIF1 1 ALS(0.985)PELGT(0.015)K;ALS(0.993)PELGT(0.007)K 70.977 0.03622 6701900.0 70082.0 76851.0 73290.0 60916.0 73464.0 80769.0 68109.0 67480.0 71863.0 57206.0 True False 69082.61782853513 76673.05623121152 67264.37910758123 65395.96584981896 69142.99195578112 77314.69815173495 71635.35076010351 70615.36714785143 63769.032189061676 67093.98087779632 1.0296395730991261 1.1427710090844414 1.00253969473201 0.9746919916546599 1.030539417264819 1.152334339686215 1.067686695928488 1.052484384202346 0.9504434131760546 1.0 16.03389572500233 -8.243833779599345 18.76332269542014 0.9752220159714505 1.0576209912010792 0.26734486368555876 0.05385565478772803 39.691830389923346 42305.98940769954 0.03908416819248441 0.014579048886911784 5.703825367915284e-09 8.243833779599345 0.08239897522962869 ALS(ph)PGLEESGLGLLAR ddPTM_PC-9_AZD4547_30min_R2 4 ALSPGLEESGLGLLAR 16 0 H9KVB4;O15417;O15417-2 H9KVB4 TNRC18 Trinucleotide repeat-containing gene 18 protein 1 ALS(1)PGLEESGLGLLAR;ALS(1)PGLEESGLGLLAR;ALS(1)PGLEESGLGLLAR;ALS(1)PGLEESGLGLLAR 204.67 6.802000000000001e-17 37715500.0 20615.9 21427.9 33044.2 36933.2 34594.7 27774.6 22848.4 37522.6 23114.9 27199.0 True False 27171.32736264125 28354.049629577083 32606.012317303277 28418.821352251838 29791.82305298919 26037.849871308543 24881.8633367842 31724.34435356953 24336.70642399637 26246.77128873128 1.0352255164545483 1.0802871453278726 1.2422866019830126 1.0827549430604861 1.1350662039631494 0.9920401098053369 0.9479971103137899 1.2086951192808228 0.9272266731887524 1.0 14.679852342052945 -6.7557189133902975 24.961769996500617 1.0240355766755076 1.118455005694631 0.24363043802386553 0.08724850222546014 218.23393968910628 952283.1763655246 0.028999781161606463 0.028245904807512514 1.7550160260488255e-07 6.7557189133902975 0.09441942901912337 ALS(ph)PGLEESGLGLLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ALSPGLEESGLGLLAR 16 0 H9KVB4;O15417;O15417-2 H9KVB4 TNRC18 Trinucleotide repeat-containing gene 18 protein 1 ALS(1)PGLEESGLGLLAR;ALS(1)PGLEESGLGLLAR;ALS(1)PGLEESGLGLLAR;ALS(1)PGLEESGLGLLAR 205.66 5.9848e-17 28473600.0 25316.4 26088.1 29614.1 30195.200000000004 35715.399999999994 32156.4 28852.4 27071.9 30525.9 21173.8 True False 29601.966498307786 28677.95415775351 30320.21245609965 28503.460838159233 28717.223755144114 30470.061775893082 26119.2917987133 26361.291310049055 30972.283538170952 25012.442328291418 1.1834896452644765 1.1465475374756209 1.2122051920457462 1.1395712767289081 1.148117539991776 1.218196183162353 1.0442519549228477 1.0539271201130151 1.2382750605341084 1.0 14.610358315232334 -14.52287872869525 0.13563820672138321 0.4969230658501185 1.2069329826776418 0.36057715883679875 0.061493748201063334 156.08634185391585 1.3093055459865321 21.326673176843254 0.4130662803023491 3.000000114565726e-15 14.52287872869525 0.7100099168275233 ALS(ph)PGLEESGLGLLAR ddPTM_PC-9_Lapatinib_30min_R1 5 ALSPGLEESGLGLLAR 16 0 H9KVB4;O15417;O15417-2 H9KVB4 TNRC18 Trinucleotide repeat-containing gene 18 protein 1 ALS(1)PGLEESGLGLLAR;ALS(1)PGLEESGLGLLAR;ALS(0.751)PGLEES(0.249)GLGLLAR;ALS(1)PGLEESGLGLLAR;ALS(1)PGLEESGLGLLAR 224.67 1.3441999999999998e-28 38290200.0 31675.0 26797.0 32601.9 26575.5 27433.600000000002 30445.899999999998 27080.1 26115.199999999997 36435.9 21502.9 True False 31223.308691516417 26734.953192902773 29921.49762897336 28529.95092326915 25820.009584532796 29143.79982985933 28482.175074053048 27328.607530224806 32332.10525496338 25219.64761418678 1.2380549153253197 1.060084327977033 1.1864359917599188 1.1312589041577341 1.023805327478418 1.1555990105692477 1.1293645141191824 1.0836236869087605 1.282020500428231 1.0 14.62226049705472 -4.741117658816692 24.530850733044264 1.1208332629457107 1.2380554431045674 0.17701467843487928 0.0779520793186252 2069.84005873655 2498390.20986862 0.01820220470512958 0.7167773665269882 1.8150238709122284e-05 4.741117658816692 0.11722218015885666 ALS(ph)PLPTR ddPTM_PC-9_AZD4547_30min_R2 2 ALSPLPTR 8 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 ALS(0.999)PLPT(0.001)R;ALS(0.982)PLPT(0.018)R 99.68799999999999 0.0051229 25877000.0 116592.0 106920.0 156990.0 227360.0 144111.0 142239.0 164732.0 252210.0 183365.0 187340.0 True False 153665.830735746 141479.79906544188 154908.21002455606 174945.6646769837 124103.67518693117 133344.77284443533 179392.82887183098 213236.73970923576 193057.29955293314 180781.2836218578 0.8500096229937748 0.7826020273280986 0.8568819012734707 0.967720004925507 0.6864851974749787 0.7376027549586055 0.992319698576037 1.1795288507590498 1.0679053477502307 1.0 17.463885796970622 -7.46089545724152 4.708480999597923 1.0928915927497533 0.8166463066112005 0.6920634094558524 0.0819469115436556 0.1213016169028721 5.4027464984717515 0.03783837018070998 0.024251655166204755 3.4602266189149756e-08 7.46089545724152 -0.2762452861385528 ALS(ph)PLPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALSPLPTR 8 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 ALS(0.904)PLPT(0.096)R 70.55199999999999 0.037828 8602100.0 43425.0 66807.0 56994.0 73747.0 77111.0 51632.0 58491.0 68715.0 65770.0 43132.0 True False 50775.99481715469 73439.1574479185 58352.95311094865 69615.19468099988 62001.65309594517 48924.32702705873 52950.30904183155 66911.30405956082 66731.76182538437 50951.49016727586 0.996555638519207 1.4413544570887857 1.1452648964607999 1.3663034084469425 1.2168761481242485 0.9602138596229106 1.0392298413254153 1.3132354684796899 1.309711680783059 1.0 15.636836720749184 -6.5384065928371475 24.987981187938786 1.1331515456859926 1.2511396682799323 0.10495434500334655 0.1566935266474118 560.6421523009002 902199.8544695043 0.05204476600284017 0.05206023497502045 2.8946323216781477e-07 6.5384065928371475 0.11798812259393965 ALS(ph)PLPTR ddPTM_PC-9_Lapatinib_30min_R1 3 ALSPLPTR 8 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 ALS(0.992)PLPT(0.008)R;ALS(0.996)PLPT(0.004)R;ALS(0.998)PLPT(0.002)R 76.1 0.025435 17392400.0 126804.0 118896.0 133694.0 109132.0 127954.0 119415.0 105833.0 106003.0 130678.0 99439.0 True False 124995.75170699426 118620.7036169485 122702.19539376427 117157.93133367973 120427.99728724289 114307.89881996103 111312.51489515406 110928.2863629769 115959.66753965465 116626.89865586114 1.0717574860309684 1.0170955841582534 1.0520917284770637 1.0045532607309189 1.0325919549879992 0.980116080744435 0.9544326066974602 0.9511380962834353 0.9942789260119543 1.0 16.83154104240858 -6.79352335100588 3.882891770326391 0.9703451985572484 1.0343826237767344 0.6384854818978943 0.02233005023779947 0.13555335077889333 4.364798496233598 0.007811858290836694 0.007134698340474676 1.6087058791836193e-07 6.79352335100588 0.06403742521948597 ALS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 1 ALSPVR 6 0 Q02535 Q02535 ID3 DNA-binding protein inhibitor ID-3 1 ALS(1)PVR 96.19 0.034612000000000004 15406000.0 74223.0 62350.0 102130.0 117140.0 109770.0 102900.0 110140.0 123420.0 98509.0 92875.0 True False 97824.37006569319 82503.41817929583 100775.68946944353 90135.18279495911 94530.33026812285 96465.6467332618 119942.24663054789 104348.27490945601 103715.9846298907 89623.47451894982 1.091503878763475 0.9205558992454757 1.124434083931166 1.0057095340116622 1.0547496710600697 1.0763435277536053 1.3382905234854237 1.1642962457050559 1.1572412828958243 1.0 16.451589037462448 -7.018686911924453 24.104678126065224 1.1827439042904755 1.038632566803483 0.28861486103025247 0.09166452292870007 515.4353497530858 664870.3421719886 0.03285021172072256 0.025934906911290186 9.578843727188485e-08 7.018686911924453 -0.14411133748699245 ALS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 1 ALSPVR 6 0 Q02535 Q02535 ID3 DNA-binding protein inhibitor ID-3 1 ALS(1)PVR 83.75299999999999 0.043141000000000006 12335000.0 72295.0 98642.0 105630.0 91897.0 113570.0 97834.0 89543.0 92102.0 111330.0 90633.0 True False 71264.06004272086 98413.60050954648 96945.50914359145 98655.41193940518 106890.03588721076 93649.86788219295 94179.09840273618 96381.39515488164 98790.84304312708 106298.79328911853 0.6704126908467543 0.9258204864271095 0.9120094983572636 0.9280953140368736 1.005562081937131 0.8810059360455561 0.8859846428038144 0.9067026273076977 0.929369374630897 1.0 16.69776569382995 -4.761433101279644 11.085978746572493 0.9263803536306212 0.6698324792842504 0.7916241854028171 0.03998232079679876 0.029136819296469378 125.53288704878854 0.009957472636575874 0.05593819372458105 1.7320758191542024e-05 4.761433101279644 -0.25654787434637083 ALS(ph)PVTSR ddPTM_PC-9_AZD4547_30min_R2 2 ALSPVTSR 8 0 Q96L91-5;Q96L91-2;Q96L91;Q96L91-4;Q96L91-3;A0A0A0MR80;A0A0A0MR72 Q96L91-5 EP400 E1A-binding protein p400 1 ALS(0.986)PVT(0.014)SR;ALS(0.999)PVT(0.001)SR 107.21 0.0038138000000000004 98037000.0 515970.0 427370.0 587990.0 716670.0 612920.0 594750.0 508580.0 595790.0 529030.0 622110.0 True False 680037.7271572907 565508.9948241474 580192.8684141593 551452.803941124 527826.6377693162 557560.1884801487 553842.6347499911 503724.3453921946 556993.4457638495 600330.1182555474 1.1327729635377273 0.9419967075238804 0.9664563725373244 0.918582605089926 0.8792273146366313 0.9287559819592585 0.9225634661798402 0.8390789168731497 0.9278119301799708 1.0 19.195396523490963 ALS(ph)PVTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ALSPVTSR 8 0 Q96L91-5;Q96L91-2;Q96L91;Q96L91-4;Q96L91-3;A0A0A0MR80;A0A0A0MR72 Q96L91-5 EP400 E1A-binding protein p400 1 ALS(0.997)PVT(0.003)SR;ALS(0.999)PVT(0.001)SR;ALS(0.997)PVT(0.003)SR;ALS(0.997)PVT(0.003)SR 109.44 0.003778 142329000.0 957860.0 992700.0 920400.0 1130260.0 1221230.0 1059400.0 1192660.0 1110170.0 1039470.0 819120.0 True False 1120006.7794026437 1091248.6954742523 942345.8266364369 1066935.1965523625 981938.7481729067 1003843.1990328875 1079682.6106893485 1081029.2138223476 1054670.2822659612 967619.9718496467 1.1574862156490044 1.1277657832839934 0.9738800914114069 1.1026386676505557 1.0147979338374848 1.037435386036936 1.1158126558978412 1.117204321192249 1.0899633254261114 1.0 19.88408102154618 -9.258990430776134 0.006423314318775234 5.6092951264941456e-08 2.1114907861193544 0.11867251167495829 0.05545348790886028 21670.4683113736 49.53829741048557 8299.661116254742 7982.370287379475 5.5081983300958e-10 9.258990430776134 2.111490730026403 ALS(ph)PVTSR ddPTM_PC-9_Lapatinib_30min_R1 1 ALSPVTSR 8 0 Q96L91-5;Q96L91-2;Q96L91;Q96L91-4;Q96L91-3;A0A0A0MR80;A0A0A0MR72 Q96L91-5 EP400 E1A-binding protein p400 1 ALS(0.999)PVT(0.001)SR 105.2 0.003846 62809000.0 272860.0 243030.0 266970.0 228740.0 233890.0 229030.0 215780.0 221750.0 226830.0 192020.0 True False 268968.966363605 242467.278966719 245020.75713400118 245562.30265427122 220133.05004543255 219234.92079500662 226952.03258035146 232053.31453817498 201282.0167742074 225210.4011494326 1.1943008182163732 1.0766255809199328 1.087963770249776 1.0903683906292347 0.9774550772163 0.9734671208615222 1.007733352554011 1.0303845353226022 0.8937509801807594 1.0 17.78091393302808 -4.123288756449178 0.40591429688126157 0.9678118163443958 1.4660914503115994 0.7129842750348756 0.042179602800047886 5.3143439461893935 0.4578640306314039 0.0327711167350371 1.4283988497359743 7.528548344263146e-05 4.123288756449178 0.49827963396720354 ALS(ph)SAGPIPIRPPIVPVK ddPTM_PC-9_AZD4547_30min_R2 1 ALSSAGPIPIRPPIVPVK 18 1 A0A087WXN9;Q765P7 A0A087WXN9 MTSS1L MTSS1-like protein 1 ALS(0.885)S(0.115)AGPIPIRPPIVPVK 51.166000000000004 0.030148 15315000.0 11752.0 10481.0 15943.0 20976.0 18486.0 15511.0 14545.0 22763.0 16002.0 15832.0 True False 15488.891543214704 13868.778282874082 15731.585403028856 16140.307275969446 15919.537991587089 14541.094717974931 15839.476822601408 19245.50139170269 16847.833051269536 15277.726498885748 1.0138217583842961 0.9077776254134131 1.0297072279816115 1.0564600221863252 1.042009620524896 0.9517839397789625 1.036769235511359 1.259709773774673 1.1027709556456782 1.0 13.899142249309277 -7.541250585126725 24.826572250048407 1.1383921971793816 1.001216168038345 0.3512467266232774 0.07211113957623748 211.99289715389813 286470.46244632464 0.03293114260160029 0.01901664518639302 2.8757386532128866e-08 7.541250585126725 -0.13717602914103666 ALS(ph)SAGPIPIRPPIVPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALSSAGPIPIRPPIVPVK 18 1 A0A087WXN9;Q765P7 A0A087WXN9 MTSS1L MTSS1-like protein 1 ALS(0.969)S(0.031)AGPIPIRPPIVPVK;ALS(0.972)S(0.028)AGPIPIRPPIVPVK 159.4 3.7580000000000003e-06 22741000.0 35196.0 26843.0 28784.0 33599.0 39520.0 32116.0 31131.0 32299.0 24091.0 22472.6 True False 41153.987647313224 29507.795640793214 29470.319723927896 31716.556959427722 31776.33969669374 30431.780423013217 28182.046311077884 31451.185473619313 24443.285299305724 26546.704486996285 1.5502484561679666 1.1115427022306064 1.1101310047114783 1.194745546475038 1.196997529853815 1.14634870923131 1.061602442023742 1.184749146133203 0.9207653368529828 1.0 14.69624515525448 -4.7611754098802415 24.99999757341061 1.114850648197588 1.5502489313726702 0.7107957436608423 0.08528634378057688 3.3833175156239057 319838.448050303 0.020470988639917476 0.115766543547192 1.733103862351062e-05 4.7611754098802415 0.4353982831750822 ALS(ph)SAGPIPIRPPIVPVK ddPTM_PC-9_Lapatinib_30min_R1 2 ALSSAGPIPIRPPIVPVK 18 1 A0A087WXN9;Q765P7 A0A087WXN9 MTSS1L MTSS1-like protein 1 ALS(0.851)S(0.149)AGPIPIRPPIVPVK;ALS(0.841)S(0.159)AGPIPIRPPIVPVK 96.012 0.00040612 18246300.0 48591.0 42921.0 52169.0 41336.0 43298.0 42195.0 37011.0 35909.0 49119.0 37769.0 True False 47898.08342950196 42821.61906155836 47879.8661981636 44375.98733285373 40751.29676714321 40390.41821134917 38927.248483786156 37577.4632322495 43586.70097399946 44297.32132597094 1.0812862267005734 0.966686422107709 1.0808749776499977 1.0017758637436316 0.919949458507128 0.9118027231066181 0.8787720638304967 0.8483010283111256 0.9839579385231394 1.0 15.434931840709435 -6.1840130030192615 3.292536742373163 0.9124511879602678 1.0361070991620733 0.5145607523189353 0.05202132684885507 0.18975044047199818 4.007387958599479 0.015552584133074268 0.020388385149160384 6.54616574188147e-07 6.1840130030192615 0.12365591120180552 ALS(ph)SDSILSPAPDAR ddPTM_PC-9_AZD4547_30min_R2 6 ALSSDSILSPAPDAR 15 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 ALS(0.869)S(0.114)DS(0.017)ILSPAPDAR;ALS(0.395)S(0.395)DS(0.209)ILSPAPDAR;ALS(0.372)S(0.372)DS(0.257)ILSPAPDAR;ALS(0.858)S(0.124)DS(0.018)ILSPAPDAR;ALS(0.439)S(0.111)DS(0.439)ILS(0.011)PAPDAR;ALS(0.899)S(0.041)DS(0.055)ILS(0.006)PAPDAR 246.77 3.1651999999999995e-40 1458958400.0 178610.5 195561.4 287241.0 345510.0 307624.0 283621.0 285697.0 391032.0 325156.0 300382.0 True False 235404.92367080948 258772.79813838832 283431.9966600649 265858.007576287 264915.7175767595 265886.13403434836 311123.47953157435 330606.9894214421 342343.08234086935 289865.71760916524 0.8121171610511495 0.8927333672735303 0.9778044778728365 0.9171764421439843 0.913925661032994 0.9172734748606964 1.0733365852910954 1.1405522258662184 1.1810402594847762 1.0 18.145025190520187 -7.323585230017072 3.147355041565681 1.119350901180534 0.907051329355387 0.7320372626452536 0.05747809412733893 0.13219432085531754 2.595323671224929 0.02630981941436071 0.01720443452074296 4.7469512318249916e-08 7.323585230017072 -0.21229957182514703 ALS(ph)SDSILSPAPDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ALSSDSILSPAPDAR 15 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 ALS(0.874)S(0.123)DS(0.003)ILSPAPDAR;ALS(0.768)S(0.043)DS(0.179)ILS(0.01)PAPDAR;ALS(0.985)S(0.015)DSILSPAPDAR;ALS(0.946)S(0.054)DS(0.001)ILSPAPDAR;ALS(0.92)S(0.05)DS(0.03)ILSPAPDAR 184.48 4.8159e-07 931034700.0 92279.29999999999 94462.0 117210.7 118308.8 147397.9 114968.8 128488.7 156854.3 122974.6 97251.3 True False 107900.36289074626 103839.56308239042 120005.44761205484 111680.34149830489 118516.33959967867 108939.63373699457 116317.32015836929 152737.04082586867 124772.8708799136 114882.19084913276 0.9392261941839595 0.9038786805411476 1.0445957439099514 0.9721292802029459 1.0316336999119244 0.9482725993627492 1.0124921826318685 1.329510167737384 1.0860941104767894 1.0 16.809795641741758 -7.547194997557275 24.97894575592659 1.1588816562755566 0.9763420960919734 0.41716059673348505 0.08649011479582595 186.8389001634899 191928.44211885618 0.03831847170029956 0.022124337741339543 2.836645093162808e-08 7.547194997557275 -0.1825395601835832 ALS(ph)SDSILSPAPDAR ddPTM_PC-9_Lapatinib_30min_R1 5 ALSSDSILSPAPDAR 15 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 ALS(0.954)S(0.045)DSILSPAPDAR;ALS(0.493)S(0.493)DS(0.015)ILSPAPDAR;ALS(0.711)S(0.105)DS(0.077)ILS(0.106)PAPDAR;ALS(0.977)S(0.018)DS(0.004)ILSPAPDAR;ALS(0.967)S(0.024)DS(0.01)ILSPAPDAR 189.33 2.104e-07 678170700.0 100563.4 106807.1 106315.3 98376.1 129481.1 108311.3 100830.1 100564.5 117433.2 99700.3 True False 99129.34747493095 106559.79472215874 97574.46642292583 105611.0065670494 121865.27626763709 103679.07818497226 106050.58921253176 105237.09379875688 104206.63638958185 116933.36401270107 0.8477422018249959 0.9112864888637294 0.8344450469442364 0.9031725672031305 1.0421771176821726 0.8866509491141539 0.9069318248726066 0.8999749103885032 0.8911625631352155 1.0 16.835327100012833 -5.9975226036318325 24.991486998046323 0.9327090650994035 0.8691104283309901 0.2938830509018753 0.05052908784131017 114.60993609400091 1156123.8880600757 0.014402326877771425 0.021217535662843914 1.0057207171088897e-06 5.9975226036318325 -0.06359863676841349 ALS(ph)SESFER ddPTM_PC-9_AZD4547_30min_R2 1 ALSSESFER 9 0 Q15120;Q15120-2 Q15120 PDK3 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial 1 ALS(0.498)S(0.498)ES(0.005)FER 72.138 0.033093 7991600.0 55365.0 47003.0 62329.0 91708.0 80455.0 64231.0 59809.0 69767.0 55601.0 68454.0 True False 72969.91833646034 62195.80055623798 61502.47673495489 70566.13747447584 69285.21200438919 60214.62541617228 65131.88513461448 58986.113236169345 58539.95534830881 66057.44629577608 1.1046433434579541 0.9415410986030649 0.931045327722388 1.0682540944515448 1.048863010752196 0.911549398179242 0.9859885415942762 0.8929517646209871 0.8861976753717171 1.0 16.01143357733467 -6.768500204901726 24.997532377752066 0.9318126455832306 1.0124378429943057 0.32189289924902453 0.06015084070210612 220.33717615008615 780057.8907706024 0.021560133545586193 0.01941056060130299 1.7041185153059946e-07 6.768500204901726 0.0806251974110751 ALS(ph)SGGSITSPPLSPALPK ddPTM_PC-9_AZD4547_30min_R2 1 ALSSGGSITSPPLSPALPK 19 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1;C9JW88;C9JHT0;C9JRZ2;C9JXQ0;C9JPV7;F8WCD5;C9J0V6 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 ALS(0.54)S(0.145)GGS(0.121)IT(0.072)S(0.122)PPLSPALPK 73.383 0.0027938000000000004 26173000.0 107910.0 96292.0 142740.0 179100.0 162780.0 143430.0 130910.0 145950.0 126720.0 149260.0 True False 142223.1353325644 127416.50590730946 140847.17433534082 137811.26206741633 140180.80678732786 134461.29942615854 142560.7363937261 123396.78109735138 133418.16049599252 144034.4528312079 0.9874244150407114 0.8846251948943578 0.9778714159479455 0.9567937348220121 0.9732449704349829 0.9335356699950949 0.9897683060648773 0.8567171164385127 0.9262933824058299 1.0 17.136054417934822 -9.834070241191426 6.6113705944083065 0.9999999994112269 0.9420993834719696 0.1418124431009825 0.0420819144797185 18160894.58462583 0.0 0.04004523398354362 0.010011308495885914 1.4653108278082363e-10 9.834070241191426 -0.057900615939257216 ALS(ph)SSVIR ddPTM_PC-9_AZD4547_30min_R2 1 ALSSSVIR 8 0 H0YJ17;Q8NEJ9-2;Q8NEJ9 H0YJ17 NGDN Neuroguidin 1 ALS(0.333)S(0.333)S(0.333)VIR 98.58200000000001 0.0054621 5234000.0 28716.0 45135.0 53663.0 67624.0 57861.0 56529.0 37392.0 59641.0 54794.0 55844.0 True False 37847.090670094745 59724.006086968955 52951.39355721867 52034.3315803851 49827.99890356058 52994.23269372736 40719.81556209774 50424.85386383781 57690.298975831894 53888.918557590725 0.7023167597926059 1.1082799151581102 0.9826026384372488 0.9655850028754309 0.9246427695577104 0.9833975910482 0.755625027408571 0.9357184225166647 1.0705410410895269 1.0 15.71770101457446 -8.213091197316292 8.288096684987309 1.035062892527221 0.9263442558441572 0.14592132640389743 0.11088857315729737 0.6106987369557273 98.90938395245988 0.07458254197666689 0.027760188804835984 6.122218180226226e-09 8.213091197316292 -0.1087186366830637 ALS(ph)SSVIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALSSSVIR 8 0 H0YJ17;Q8NEJ9-2;Q8NEJ9 H0YJ17 NGDN Neuroguidin 1 ALS(0.333)S(0.333)S(0.333)VIR 104.06 0.0038641999999999995 2939300.0 29989.0 27519.0 36709.0 28850.0 43793.0 40949.0 38381.0 43147.0 36284.0 23869.0 True False 35065.54539025105 30250.904453264866 37584.281779657766 27233.628032961984 35212.076020680885 38801.56235340539 34745.27382562338 42014.43696802537 36814.584857415975 28196.26075309997 1.243623957704954 1.0728693679689072 1.3329526957054278 0.9658595610046573 1.2488207684350336 1.3761243979537054 1.2322653038950704 1.49007123093108 1.3056548589822672 1.0 14.783216231866941 -6.514859743724054 24.653271180632302 1.3088683002557844 1.1541511953099646 0.12818175634327322 0.1485502217045235 510.1773095867073 1568472.9904488218 0.044998053532027425 0.04703582323784897 3.055907865458236e-07 6.514859743724054 -0.1547171049458198 ALS(ph)SSVIR ddPTM_PC-9_Lapatinib_30min_R1 2 ALSSSVIR 8 0 H0YJ17;Q8NEJ9-2;Q8NEJ9 H0YJ17 NGDN Neuroguidin 1 ALS(0.333)S(0.333)S(0.333)VIR;ALS(0.428)S(0.428)S(0.144)VIR 90.601 0.009352899999999999 9490200.0 97022.0 80509.0 100728.0 89358.0 98384.0 87028.0 81108.0 71950.0 101714.0 82161.0 True False 95638.44848834405 80322.5863569581 92446.53266132403 95929.68540954981 92597.24655038613 83306.01531217658 85307.37537550817 75293.05966638864 90257.89822409612 96362.41937734914 0.9924869996656054 0.8335468004639851 0.9593629265295763 0.9955093077716867 0.9609269583382 0.8645073032668004 0.8852763964077104 0.7813529397964343 0.9366503955307711 1.0 16.55618299541606 -6.761883798018194 24.99999995036904 0.8793743975572683 0.9452176714297627 0.12453499097959397 0.0673617413543719 21.025528220185034 1182718.820097533 0.02264867049052678 0.021209205840322785 1.7302792593698049e-07 6.761883798018194 0.06584327387249433 ALS(ph)TTSSSTTNGNR ddPTM_PC-9_AZD4547_30min_R2 4 ALSTTSSSTTNGNR 14 0 A0A0A0MT72;Q9BSQ5-4;Q9BSQ5;Q9BSQ5-2;C9JUH3;Q9BSQ5-3 A0A0A0MT72 CCM2 Cerebral cavernous malformations 2 protein 1 ALS(0.994)T(0.004)TSSST(0.001)TNGNR;ALS(0.725)T(0.241)T(0.012)S(0.006)S(0.006)S(0.009)TTNGNR;ALS(0.839)T(0.159)T(0.002)SSSTTNGNR;ALS(0.496)T(0.496)T(0.007)SSSTTNGNR 173.33 2.9224e-05 27079300.0 73363.1 70823.7 85063.0 133980.0 131063.0 99721.0 86218.0 125076.0 89018.4 102347.7 True False 96691.03975272419 93716.07599206084 83935.00904082322 103092.98097036534 112867.16476205658 93485.43010580752 93891.23497360227 105748.37816055011 93723.73088933463 98764.5381752152 0.9790056384528171 0.948883857744588 0.849849658507152 1.0438258799678806 1.1427903865841231 0.9465485470094319 0.9506573584846076 1.070712019864307 0.9489613642809951 1.0 16.591705508582343 -5.784612219492164 24.999892998773383 1.017549801540396 0.9282100706100888 0.2780867632498736 0.0654812774626639 303.26611931095715 327175.8912032563 0.01912060443842987 0.028380551223290074 1.6420553060860484e-06 5.784612219492164 -0.08933973093030734 ALS(ph)TTSSSTTNGNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALSTTSSSTTNGNR 14 0 A0A0A0MT72;Q9BSQ5-4;Q9BSQ5;Q9BSQ5-2;C9JUH3;Q9BSQ5-3 A0A0A0MT72 CCM2 Cerebral cavernous malformations 2 protein 1 ALS(0.427)T(0.427)T(0.132)S(0.005)S(0.005)S(0.005)TTNGNR;ALS(0.332)T(0.332)T(0.332)S(0.002)S(0.002)S(0.002)TTNGNR 162.94 0.00056002 11605200.0 46748.0 47653.0 47005.0 52314.0 62818.0 52619.0 51722.0 51367.0 45429.0 33993.9 True False 54661.51308491306 52383.674912294395 48125.777467455184 49383.01618427635 50509.263842786124 49859.56700954451 46822.51772514764 50018.67067783531 46093.31318177574 40156.724974435674 1.3612044587727543 1.3044807549829467 1.19844876538345 1.2297570634984367 1.2578033660598822 1.2416243366779984 1.1659944319402418 1.2455864045107734 1.1478354674371323 1.0 15.293353993066075 -14.52287874528012 0.08426179550724103 0.20839638705800723 1.4591734471126474 0.811535262798594 0.04037309949442768 105.38389018072829 0.6215363320011448 15.19677009229606 1.2477917298775676 3.0000000000014983e-15 14.52287874528012 1.2507770600546402 ALS(ph)TTSSSTTNGNR ddPTM_PC-9_Lapatinib_30min_R1 4 ALSTTSSSTTNGNR 14 0 A0A0A0MT72;Q9BSQ5-4;Q9BSQ5;Q9BSQ5-2;C9JUH3;Q9BSQ5-3 A0A0A0MT72 CCM2 Cerebral cavernous malformations 2 protein 1 ALS(0.49)T(0.49)T(0.018)S(0.001)S(0.001)S(0.001)TTNGNR;ALS(0.885)T(0.111)T(0.003)S(0.001)S(0.001)S(0.001)TTNGNR;ALS(0.922)T(0.076)T(0.002)SSSTTNGNR;ALS(0.981)T(0.017)T(0.002)SSSTTNGNR 190.37 2.1784e-06 21711000.0 91098.3 74639.0 89193.7 79310.5 92422.3 83991.2 69365.1 69621.4 92799.4 82741.2 True False 89799.22153661793 74466.17798130652 81860.53828363851 85143.25874207205 86986.20202323291 80399.09216905008 72956.48547195914 72856.26440941634 82347.3543509958 97042.90617428099 0.9253558562574992 0.7673531318978789 0.8435499462126969 0.8773774621831898 0.8963684771250866 0.8284901528470304 0.7517961729313357 0.7507634229190596 0.8485664495981479 1.0 16.566335135494704 -6.988872005840039 24.46200730989105 0.8131734178465432 0.8571576978549381 0.0 0.07659396583117958 499.6868190182982 1098425.3305199118 0.026146410390256447 0.023038527866973767 1.0259542483138849e-07 6.988872005840039 0.04398428000839494 ALS(ph)YASLDKEDLLSPINQNTLQR ddPTM_PC-9_AZD4547_30min_R2 1 ALSYASLDKEDLLSPINQNTLQR 23 1 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 ALS(0.81)Y(0.169)AS(0.021)LDKEDLLS(0.001)PINQNTLQR 51.773 0.011077 14081000.0 6452.1 7561.0 7428.3 12575.0 13601.0 10092.0 8456.2 8316.5 11326.0 11326.0 True False 8503.73358798294 10004.945386586292 7329.795888435002 9676.028031813295 11712.73592034924 9460.945644626587 9208.785418169959 7031.376019158082 11924.669237512722 10929.480187366093 0.7780547146069043 0.9154090784803733 0.670644510331595 0.8853145681162657 1.0716645000087515 0.8656354632092151 0.8425638969376451 0.6433403875223622 1.091055478676563 1.0 13.415937166749346 -14.522878744797904 0.12759526673389876 1.4780919391838288 0.7965886174016679 0.12214201539577696 0.13534432230624344 376.3732227113653 3.038863178577734 45.89029456818668 1.1104444517988825 3.000000003332535e-15 14.522878744797904 -0.6815033217821609 ALS(ph)YASLDKEDLLSPINQNTLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALSYASLDKEDLLSPINQNTLQR 23 1 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 ALS(0.838)Y(0.148)AS(0.014)LDKEDLLSPINQNTLQR 57.673 0.0035459000000000003 7943200.0 11731.0 11820.0 8934.3 17693.0 13227.0 14025.0 19551.0 10489.0 13757.0 13342.0 True False 13716.826602188634 12993.411484341388 9147.327595521432 16701.71857147994 10635.264300813977 13289.504310398555 17698.987743017704 10213.674864014141 13958.170099312976 15760.798984786119 0.8703128956488482 0.8244132481407772 0.5803847637642823 1.05969999284948 0.6747922050830154 0.8431999115797936 1.1229752857137836 0.6480429624077682 0.885625793006229 1.0 13.944053052806344 -7.004644291459815 24.939207891691957 0.8988678717968885 0.8005649721864669 0.09430779440331039 0.16137624152950406 556.8930330734673 2990451.057623365 0.056542942544271016 0.0486012611134609 9.893630999323573e-08 7.004644291459815 -0.0983028996104216 ALSAS(ph)HTDLAH ddPTM_PC-9_AZD4547_30min_R2 5 ALSASHTDLAH 11 0 Q07866-6;Q07866-4;Q07866-7;H0YG16;H0YJK1 Q07866-6 KLC1 Kinesin light chain 1 1 ALS(0.011)AS(0.758)HT(0.231)DLAH;ALSAS(0.94)HT(0.06)DLAH;ALS(0.001)AS(0.971)HT(0.028)DLAH;ALS(0.197)AS(0.764)HT(0.039)DLAH;ALS(0.125)AS(0.601)HT(0.274)DLAH 116.74 0.00069784 349365200.0 182674.0 186133.0 386427.0 568383.0 413117.0 369731.0 295910.0 453966.0 311959.0 350799.0 True False 240760.53214475798 246296.85222079963 381302.7254930832 437351.0807798122 355762.8354684897 346611.66212182294 322245.4167463718 383815.9858008914 328448.51586307876 338517.6337849053 0.7112200609842902 0.727574659751099 1.12638955090701 1.2919595233189707 1.0509432891006854 1.023910211844564 0.9519309618923044 1.1338138622485137 0.9702552631919185 1.0 18.368871461889725 -5.255449580772405 24.51905260555449 1.0750059257087696 0.7193972880894547 0.6882942790941435 0.0939345924724695 208.6629235099044 854146.4043812345 0.025622030290328855 0.06406924312035728 5.553290840640632e-06 5.255449580772405 -0.35560863761931494 ALSAS(ph)HTDLAH ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ALSASHTDLAH 11 0 Q07866-6;Q07866-4;Q07866-7;H0YG16;H0YJK1 Q07866-6 KLC1 Kinesin light chain 1 1 ALS(0.04)AS(0.902)HT(0.058)DLAH;ALSAS(0.764)HT(0.235)DLAH;ALS(0.014)AS(0.931)HT(0.055)DLAH;ALS(0.015)AS(0.947)HT(0.038)DLAH;ALS(0.007)AS(0.974)HT(0.02)DLAH 145.25 0.00019848 421245000.0 210539.0 237730.0 375609.0 359563.0 409332.0 366634.0 345660.0 348903.0 340727.0 259504.0 True False 246179.09436520294 261330.26329716414 384564.9430650654 339417.85082897445 329126.33301434835 347407.0676177304 312916.5824383145 339744.66594328615 345709.4877828462 306550.0209674657 0.803063374741475 0.8524881599172985 1.2544932857984683 1.1072184883816956 1.0736464214735078 1.1332801952559672 1.0207684261470806 1.1082845953526892 1.1277425024855454 1.0 18.22576297776122 -5.142775874023755 6.4619497469906015 1.1038310238199622 0.8168045262061566 0.7382371669400296 0.06578627124105477 0.10771139761013561 5.232544064674161 0.016352208136792598 0.04454849014865096 7.198203592341436e-06 5.142775874023755 -0.2870264976138056 ALSAS(ph)HTDLAH ddPTM_PC-9_Lapatinib_30min_R1 5 ALSASHTDLAH 11 0 Q07866-6;Q07866-4;Q07866-7;H0YG16;H0YJK1 Q07866-6 KLC1 Kinesin light chain 1 1 ALSAS(0.989)HT(0.011)DLAH;ALS(0.043)AS(0.827)HT(0.13)DLAH;ALS(0.001)AS(0.8)HT(0.199)DLAH;ALS(0.213)AS(0.738)HT(0.049)DLAH;ALSAS(0.943)HT(0.057)DLAH 107.55 0.0020883000000000004 303042000.0 308736.9 222301.8 357046.0 250926.8 292603.0 306692.0 251709.2 245974.0 321598.0 207572.3 True False 304334.25519058603 221787.07384028158 327691.05611741747 269380.79393926624 275392.666819632 293575.4980939704 264741.4707534255 257402.85001223464 285376.24666292605 243450.89548229598 1.2500847638603882 0.911013588185426 1.3460252650467146 1.106509768245465 1.1312041644950896 1.2058920445224632 1.0874532633324316 1.057309111565594 1.1722127622392702 1.0 17.893271281700216 -10.172810747356818 0.3469371776854134 0.9500192071240088 1.1513090233380014 0.13180075417426074 0.11065238632263256 21.24632681895411 2.3944390713945687 1.2850074833924199 0.09042104627063356 6.717215054487018e-11 10.172810747356818 0.20128981621399267 ALSGGGSVAS(ph)PPPSPAMPK ddPTM_PC-9_AZD4547_30min_R2 3 ALSGGGSVASPPPSPAMPK 19 0 O75420 O75420 GIGYF1 PERQ amino acid-rich with GYF domain-containing protein 1 1 ALSGGGS(0.002)VAS(0.968)PPPS(0.03)PAMPK;ALSGGGSVAS(0.989)PPPS(0.011)PAMPK;ALSGGGS(0.002)VAS(0.934)PPPS(0.064)PAMPK 148.33 4.3942e-05 11413200.0 54850.0 53877.0 80545.0 98477.0 86604.0 80112.0 52538.0 70859.0 62837.0 76344.0 True False 72291.15904912574 71291.68662784153 79476.92067283194 75774.6491044834 74580.5294938553 75102.5839756566 57213.78022040788 59909.36972783293 66158.43553572202 73671.21979730518 0.9812673015055748 0.9677006410914525 1.078805548374253 1.0285515743185123 1.0123428076669823 1.01942908210682 0.776609649980313 0.8131991012591372 0.8980228061615728 1.0 16.168813509522437 -7.242912477905225 24.416642441751957 0.8563911517951914 1.015985990802349 0.5560331334172854 0.06184943244730856 397.7987560136331 524260.2950243382 0.023241894236697095 0.017966999490872094 5.715938166930601e-08 7.242912477905225 0.15959483900715754 ALSGGGSVAS(ph)PPPSPAMPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALSGGGSVASPPPSPAMPK 19 0 O75420 O75420 GIGYF1 PERQ amino acid-rich with GYF domain-containing protein 1 1 ALSGGGSVAS(0.987)PPPS(0.013)PAMPK;ALSGGGSVAS(0.625)PPPS(0.375)PAMPK 156.67 1.3391e-05 7694600.0 33883.5 38561.0 40459.0 50211.0 63275.0 67579.0 67588.0 63513.0 58065.0 50660.0 True False 39619.30732036986 42389.08123922909 41423.69600161196 47397.84045625836 50876.717973388055 64035.03827396973 61185.575345254954 61845.8510475861 58914.090776812336 59844.25697566064 0.6620402578727562 0.7083232941879323 0.6921916670877786 0.7920198670949431 0.8501520537564734 1.070028128179677 1.022413485226157 1.0334467194193677 0.9844568844889057 1.0 15.86892518343866 -6.3725586044994795 1.6260860260510928 1.0255594591176733 0.6915442497756488 0.9416412786559416 0.03632555123783675 0.07849509603488747 0.4141899600903943 0.013310322379585342 0.01642949470549674 4.240737547535895e-07 6.3725586044994795 -0.33401520934202455 ALSGTS(ph)PDDVQPGPSVGPPSK ddPTM_PC-9_AZD4547_30min_R2 1 ALSGTSPDDVQPGPSVGPPSK 21 0 A0A075B797;M0R3B2;Q9Y314 A0A075B797 NOSIP Nitric oxide synthase-interacting protein 1 ALSGT(0.001)S(0.999)PDDVQPGPSVGPPSK 260.98 2.7289999999999986e-164 0.0 28383.0 30216.0 35195.0 40192.0 35330.0 41348.0 29985.0 44156.0 34698.0 31480.0 True False 37408.20359692502 39982.731093915005 34728.291303995524 30926.35536020996 30425.039340191048 38762.503023585065 32653.606911358056 37332.70480393726 36532.065442629064 30377.894781766267 1.231428440504658 1.316178470600071 1.1432092827196338 1.0180545947105228 1.0015519363261827 1.276010181154867 1.0749134245786427 1.2289431203884964 1.2025871346607178 1.0 14.890734272656614 -5.340731704612481 5.940625917575837 1.1217196556044278 1.273078728062295 0.30685863577539285 0.09373036145495775 0.2658872759035124 15.54345805481103 0.025298724260839973 0.053941472807496754 4.563187302663196e-06 5.340731704612481 0.15135907245786728 ALSIS(ph)PLSDASLDLQR ddPTM_PC-9_Lapatinib_30min_R1 1 ALSISPLSDASLDLQR 16 0 P10070 P10070 GLI2 Zinc finger protein GLI2 1 ALS(0.229)IS(0.714)PLS(0.016)DAS(0.041)LDLQR 110.22 0.00059581 1516800.0 14119.0 12978.0 12419.0 15515.0 11555.0 11771.0 11876.0 13498.0 12038.0 12355.0 True False 13917.660470892512 12947.95023836594 11397.957758726325 16656.024856522763 10875.357618004067 11267.581769541195 12490.88117028572 14125.166356871634 10682.153674240222 14490.545287997315 0.9604649234574126 0.893544720438566 0.7865789404189906 1.1494408612986524 0.7505140353146166 0.777581626198309 0.8620021484375788 0.9747850116152407 0.7371809315615178 1.0 13.82282426495414 -4.795573825393906 4.641298969221421 0.8773334616906714 0.9643680690761963 0.03597238982791251 0.12361061300007109 0.6918627203438156 31.64916123692941 0.030077680021339797 0.1817618500360298 1.6011284505828042e-05 4.795573825393906 0.08703460738552493 ALSQTVPSSGTNGVSLPADCTGAVPAAS(ph)PDTAAWR ddPTM_PC-9_AZD4547_30min_R2 1 ALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWR 35 0 B7Z7F3;Q9H6Z4-3;Q9H6Z4-2;Q9H6Z4;K7EN31 B7Z7F3 RANBP3 Ran-binding protein 3 1 ALSQTVPSSGTNGVS(0.003)LPADCT(0.016)GAVPAAS(0.914)PDT(0.067)AAWR 90.38 2.4108e-12 8774000.0 16136.0 14580.0 22403.0 32617.0 30609.0 24692.0 22114.0 25973.0 21070.0 25188.0 True False 21266.912350349943 19292.699872560268 22105.92158213983 25097.65457762659 26359.46869979926 23148.005336615133 24082.103159505517 21959.469650164483 22183.717184742472 24306.17578663052 0.8749592094223104 0.793736540125416 0.9094775655452583 1.0325628678877332 1.0844761813291148 0.9523507745446146 0.9907812471574302 0.9034522683837073 0.9126782172350002 1.0 14.569035304275076 -5.519383892293562 5.227564047643559 0.9814293037542328 0.8368274340868966 0.5523492349807593 0.0535725639965938 0.13399388840771528 11.43809920663517 0.015904246187749906 0.03069933877578103 3.0242389863059334e-06 5.519383892293562 -0.14460186966733612 ALSQTVPSSGTNGVSLPADCTGAVPAAS(ph)PDTAAWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWR 35 0 B7Z7F3;Q9H6Z4-3;Q9H6Z4-2;Q9H6Z4;K7EN31 B7Z7F3 RANBP3 Ran-binding protein 3 1 ALSQTVPSSGTNGVS(0.002)LPADCT(0.043)GAVPAAS(0.939)PDT(0.017)AAWR;ALSQTVPSSGTNGVS(0.005)LPADCT(0.448)GAVPAAS(0.53)PDT(0.017)AAWR 132.71 1.4141e-24 10501100.0 88996.0 91804.0 108230.0 109189.0 114756.0 108713.0 118275.0 91827.0 96666.0 93126.0 True False 104061.26504887728 100917.69440850055 110810.61366456078 103071.49432551417 92270.38558283866 103011.89890170125 107071.13576315378 89416.63854874873 98079.55737589499 110009.0066149897 0.945934048955388 0.9173584737629076 1.0072867401882515 0.9369368699623342 0.8387530114308477 0.93639513773834 0.9732942697854013 0.8128119805834599 0.8915593404015957 1.0 16.747262118794517 -6.010237114464364 24.75008539179668 0.9025742029050599 0.956109990558171 0.12330766217572675 0.056668322023897086 827.1208905967184 1999725.592226979 0.016263089987248132 0.02255403440091518 9.767038182869809e-07 6.010237114464364 0.05353578765311118 ALSQTVPSSGTNGVSLPADCTGAVPAAS(ph)PDTAAWR ddPTM_PC-9_Lapatinib_30min_R1 1 ALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWR 35 0 B7Z7F3;Q9H6Z4-3;Q9H6Z4-2;Q9H6Z4;K7EN31 B7Z7F3 RANBP3 Ran-binding protein 3 1 ALSQTVPS(0.001)S(0.001)GT(0.001)NGVS(0.019)LPADCT(0.087)GAVPAAS(0.826)PDT(0.066)AAWR 79.857 1.0599000000000001e-08 7461200.0 17035.0 13206.0 18911.0 14255.0 16925.0 18810.0 15672.0 14083.0 20719.0 14360.0 True False 16792.077776163595 13175.422318374227 17356.210578571037 15303.360253285991 15929.504775830279 18005.540148251624 16483.419476315074 14737.34759251913 18385.40803925761 16842.106866502745 0.9970295230438981 0.782290625680497 1.0305249049981267 0.9086369285378918 0.9458142560247293 1.0690788445276305 0.9787029382350575 0.8750299300041987 1.0916334984089393 1.0 14.039785003448406 -5.919784457158387 1.080678343376638 0.9911800846637832 0.9055353613167457 0.122540918568244 0.08301556538022038 1.16486904595274 2.729199101413767 0.03174899385713918 0.07232404230929051 1.2028612734451135e-06 5.919784457158387 -0.08564472334703743 ALSS(ph)AGPIPIRPPIVPVK ddPTM_PC-9_AZD4547_30min_R2 1 ALSSAGPIPIRPPIVPVK 18 1 A0A087WXN9;Q765P7 A0A087WXN9 MTSS1L MTSS1-like protein 1 ALS(0.217)S(0.783)AGPIPIRPPIVPVK 104.84 0.00016821 14166000.0 16825.0 14717.0 19527.0 26311.0 26683.0 18582.0 23321.0 28098.0 20783.0 20973.0 True False 22175.000018259645 19473.982443379242 19268.059221284846 20245.40545089777 22978.526032106376 17420.0646025021 25396.523821236657 23756.099727806613 21881.546950664582 20238.74165368437 1.095670886940878 0.9622131047773957 0.9520383999653054 1.000329259463233 1.135373257157183 0.8607286411668217 1.2548469789184415 1.173793318493293 1.0811713161367 1.0 14.304831972623926 -7.268937253345732 24.999780831070623 1.1419356705048296 1.0031370296297213 0.2981373141156687 0.093928026183406 680.3753905392607 2268530.027019685 0.03751545389668302 0.02587720855910331 5.383475570893999e-08 7.268937253345732 -0.1387986408751083 ALSS(ph)DSILSPAPDAR ddPTM_PC-9_Lapatinib_30min_R1 1 ALSSDSILSPAPDAR 15 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 ALS(0.242)S(0.739)DS(0.018)ILSPAPDAR 204.17 9.021e-13 151440000.0 43229.0 42385.0 38727.0 42219.0 54210.0 39811.0 41519.0 32241.0 42722.0 38887.0 True False 42612.54653277231 42286.86013662662 35543.01555054308 45323.92609845535 51021.474380960695 38108.3763339737 43668.65066597277 33739.034561557164 37910.1984773958 45608.56613632957 0.9343101558027105 0.9271692517196448 0.7793056998174568 0.9937590662897974 1.118681833330416 0.8355530454534157 0.957465984250455 0.7397521435053904 0.8312078560873322 1.0 15.477017194329122 -10.335313386500673 5.254177605674128 1.0000000444623829 0.9030382980322519 0.07231252221962814 0.10532853031418313 7.226467010699129e-08 1.6384345215521677e-08 0.10698421868834226 0.025947469462679288 4.620474880305519e-11 10.335313386500673 -0.096961746430131 ALSS(ph)GGS(ph)ITSPPLSPALPK ddPTM_PC-9_AZD4547_30min_R2 1 ALSSGGSITSPPLSPALPK 19 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1;C9JW88;C9JHT0;C9JRZ2;C9JXQ0;C9JPV7;F8WCD5;C9J0V6 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 2 ALS(0.026)S(0.776)GGS(0.633)IT(0.264)S(0.26)PPLS(0.04)PALPK 83.226 0.019444 3757500.0 11939.0 8845.3 13177.0 19522.0 15055.0 14830.0 13837.0 16606.0 12437.0 14931.0 True False 15735.353653373077 11704.370245730945 13002.264370301144 15021.504511893381 12964.873118216152 13902.677755629438 15068.46619417914 14039.92426791789 13094.394429361271 14408.270234642701 1.0921056724449536 0.8123369464288224 0.9024167480589717 1.0425612698307283 0.8998216237674318 0.9649095643835417 1.0458206258478613 0.9744351014572745 0.9088109964704578 1.0 13.814609524659941 -6.997756173108703 24.93926423509998 0.983740391346015 0.9434886458863264 0.032872064531803025 0.07906719693184268 238.41594856915253 2649847.865292244 0.02771469521738207 0.02428661696105972 1.0051799722568316e-07 6.997756173108703 -0.04025174545968857 ALSSDS(ph)ILSPAPDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALSSDSILSPAPDAR 15 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 ALS(0.094)S(0.316)DS(0.59)ILSPAPDAR;ALS(0.262)S(0.262)DS(0.477)ILSPAPDAR 233.28 8.772199999999999e-32 301802000.0 85706.0 97951.0 103827.0 110673.0 158214.0 120848.0 108412.0 168264.0 117736.0 92875.0 True False 100214.33302933942 107674.927944393 106302.62944609023 104472.35061670703 127213.10244870195 114510.51813925449 98142.43052508979 163847.24829044502 119457.66626537107 109712.50230190446 0.9134267373974556 0.9814280568325339 0.9689199244910939 0.9522374244023922 1.1595132713192495 1.043732626060674 0.8945419023897896 1.4934236741731926 1.088824552890518 1.0 16.74336841203948 -6.5836785628822785 0.7578363830443304 1.1648088940809922 0.9396707268393859 0.18412400910901539 0.15014642136889714 1.0530243836389126 1.3459292137760022 0.09868961154059262 0.11760697575461351 2.608083172889182e-07 6.5836785628822785 -0.2251381672416063 ALSSDS(ph)ILSPAPDAR ddPTM_PC-9_Lapatinib_30min_R1 3 ALSSDSILSPAPDAR 15 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 ALS(0.152)S(0.375)DS(0.461)ILS(0.012)PAPDAR;ALS(0.021)S(0.021)DS(0.898)ILS(0.06)PAPDAR;ALS(0.133)S(0.262)DS(0.531)ILS(0.075)PAPDAR 153.0 0.00015352 505969200.0 60714.0 61860.0 71037.0 61744.0 61667.0 56952.0 55091.7 63520.0 66790.0 59851.7 True False 59848.20722641597 61716.76697066708 65196.612070749776 66284.85973194601 58039.86830198674 54516.295721596296 57944.07866024165 66471.37109116069 59267.40687012006 70196.98659762274 0.8525751620859856 0.8791939648981619 0.9287665358694712 0.9442693047765498 0.8268142425354806 0.7766187462446218 0.8254496591482454 0.9469262757984511 0.8443012975734656 1.0 16.09912147968075 -10.832037127253528 3.882582112602913 1.0002687407020905 0.8706701263456306 0.3496118868703342 0.05340067619900785 42326395.97476068 43.51258693689046 101717.85146569466 0.014122019412452017 1.4721866417889274e-11 10.832037127253528 -0.12959861435645992 ALSSDSILS(ph)PAPDAR ddPTM_PC-9_AZD4547_30min_R2 4 ALSSDSILSPAPDAR 15 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 ALSSDS(0.001)ILS(0.998)PAPDAR;ALSSDSILS(1)PAPDAR;ALSS(0.004)DS(0.018)ILS(0.978)PAPDAR;ALSSDSILS(1)PAPDAR 215.37 1.0794000000000001e-17 88961000.0 105517.0 97451.0 112903.0 147288.0 131302.0 118964.0 93858.0 127411.0 98407.0 109170.0 True False 139069.21111005687 128950.12999182928 111405.83245049036 113333.0271769159 113072.98373749723 111525.16227381652 102211.18017296155 107722.55756351238 103608.59311812786 105347.99152876188 1.3200936163276402 1.2240397573846826 1.0575031458485336 1.0757967525747651 1.0733283292508362 1.058635866288615 0.970224288946753 1.022540211733436 0.9834890216188019 1.0 16.68480328371195 -1.5228787452877193 0.4641210332497829 0.9998960613756877 9.41686770149606 0.9194936500100775 0.029821118018880915 24.045143009671047 0.2803092543218482 0.018624701471679116 193.47375122190033 0.02999999999949009 1.5228787452877193 8.416971640120371 ALSSDSILS(ph)PAPDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ALSSDSILSPAPDAR 15 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 ALSS(0.004)DS(0.004)ILS(0.991)PAPDAR;ALSSDSILS(1)PAPDAR;ALSSDSILS(1)PAPDAR;ALS(0.008)S(0.018)DS(0.071)ILS(0.904)PAPDAR;ALS(0.003)S(0.013)DS(0.047)ILS(0.937)PAPDAR 233.28 8.7653e-32 48716000.0 75507.3 68335.9 72319.79999999999 63202.8 93752.7 84490.2 87773.4 81191.20000000001 75802.7 66073.3 True False 88289.19455284606 75119.83653577039 74044.17830636866 59661.75202224225 75382.53144438814 80059.38517550354 79458.86812761427 79060.0170291874 76911.17108288067 78051.86625404513 1.1311605832137341 0.9624348544244733 0.9486535282240126 0.7643859767305718 0.9658004998757008 1.0257203192928699 1.0180264988025987 1.0129164211379764 0.9853854209270064 1.0 16.252145507630495 -6.538764703547315 15.136993865787021 1.0082610361489028 0.941326511014477 0.09230197774700455 0.08298046704722183 5.74969691847659 5472.687468909353 0.028879236234265665 0.02897266291428544 2.8922464484573736e-07 6.538764703547315 -0.06693452513442588 ALSSDSILS(ph)PAPDAR ddPTM_PC-9_Lapatinib_30min_R1 4 ALSSDSILSPAPDAR 15 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 ALSS(0.001)DS(0.058)ILS(0.941)PAPDAR;ALS(0.007)S(0.128)DS(0.065)ILS(0.799)PAPDAR;ALSSDSILS(1)PAPDAR;ALS(0.002)S(0.047)DS(0.009)ILS(0.942)PAPDAR 173.19 7.9536e-05 68054000.0 80986.0 86155.0 82315.0 75760.0 82702.0 89765.0 82709.0 77390.0 95261.0 76274.0 True False 79831.12478898658 85955.5133908473 75547.37844508879 81331.6431279515 77837.630958388 85925.9602024352 86991.26732175489 80985.82192608503 84531.70303719866 89457.85927128332 0.8923880521989307 0.9608492097959213 0.8445024177919278 0.9091615179535109 0.870103885700454 0.9605188510252908 0.972427330928539 0.9052957737396039 0.9449332202423271 1.0 16.44892061457812 -6.773345890422559 24.99972361101008 0.9517030492651095 0.8969737987774566 0.41992117229983794 0.03572695748823183 250.55174117918614 526072.3975091048 0.01241640817280114 0.011034499862242548 1.6852103182687402e-07 6.773345890422559 -0.05472925048765287 ALSSGGS(ph)ITSPPLS(ph)PALPK ddPTM_PC-9_AZD4547_30min_R2 1 ALSSGGSITSPPLSPALPK 19 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1;C9JW88;C9JHT0;C9JRZ2;C9JXQ0;C9JPV7;F8WCD5;C9J0V6 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 2 ALSS(0.005)GGS(0.469)IT(0.376)S(0.155)PPLS(0.995)PALPK 143.69 1.2821e-09 0.0 9436.6 8960.3 14083.0 18721.0 14786.0 14249.0 12388.0 18458.0 14168.0 14643.0 True False 12437.242506526527 11856.541746783376 13896.250218331259 14405.16268656674 12733.21912493816 13358.007777475661 13490.508001264086 15605.740222644123 14916.891555454733 14130.353026982317 0.8801791776027997 0.839083193756233 0.9834326284556351 1.0194481807396933 0.9011253364033942 0.9453414045613836 0.954718397728887 1.1044126210325045 1.0556630486846648 1.0 13.786509889376605 -3.6234309060408343 0.2725717551888803 1.0455101418974602 0.5398680905674631 0.46387621823059566 0.0565720967143871 15.995300554458154 0.5986868055219534 0.07540545880967518 3.0229602274404677 0.0002379956909417341 3.6234309060408343 -0.5056420513299971 ALSSGGS(ph)ITSPPLSPALPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALSSGGSITSPPLSPALPK 19 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1;C9JW88;C9JHT0;C9JRZ2;C9JXQ0;C9JPV7;F8WCD5;C9J0V6 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 ALS(0.001)S(0.003)GGS(0.86)IT(0.113)S(0.023)PPLS(0.001)PALPK;ALSS(0.002)GGS(0.973)IT(0.014)S(0.011)PPLSPALPK 121.04 4.0676e-05 307039600.0 148195.0 147751.0 177832.0 204553.0 223817.0 231612.0 248218.0 211184.0 216632.0 180712.0 True False 173281.486515331 162418.74282765828 182072.18931161525 193092.5585797741 179961.66553377776 219465.8589903764 224704.99409730232 205640.6437679435 219799.833172521 213473.65508459508 0.8117230505406544 0.7608374099525076 0.8529023838537074 0.9045264086720941 0.8430158066224274 1.028069992540329 1.0526122954528347 0.9633068946444584 1.0296344674729019 1.0 17.703698511383344 -6.340791492405103 0.9608230450864883 1.0189532810805624 0.7930702419926525 0.7958651704143317 0.04451391478547165 0.24788632223801513 0.4897692863624895 0.022372537244591532 0.03232614136571265 4.5625591479684194e-07 6.340791492405103 -0.22588303908790985 ALSSGGSIT(ph)SPPLS(ph)PALPK ddPTM_PC-9_Lapatinib_30min_R1 2 ALSSGGSITSPPLSPALPK 19 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1;C9JW88;C9JHT0;C9JRZ2;C9JXQ0;C9JPV7;F8WCD5;C9J0V6 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 2 ALS(0.001)S(0.019)GGS(0.129)IT(0.829)S(0.238)PPLS(0.784)PALPK;ALSSGGS(0.015)IT(0.837)S(0.424)PPLS(0.724)PALPK 119.8 0.0062778 0.0 13930.6 10228.3 9731.2 11197.9 15184.9 21039.0 21554.0 17463.6 20779.8 18551.6 True False 13731.94708944084 10204.616999774878 8931.138299518298 12021.43092109934 14291.754036662043 20139.211014304412 22669.960655468036 18275.0226100062 18439.36010300523 21758.219341546825 0.6311153901836075 0.4690005574256435 0.41047193059886533 0.5525006772105056 0.6568439178003994 0.9255909547638876 1.0419033055788836 0.8399135206395525 0.847466413200261 1.0 14.40927287307537 -6.590462613224032 2.506872196074914 0.9308780883300196 0.505595708096198 0.8633681799553097 0.0784654232683065 0.10415193121578677 1.328548716991865 0.029901732427349465 0.030694226385775222 2.5676592387036836e-07 6.590462613224032 -0.4252823802338216 ALSSGGSIT(ph)SPPLSPALPK ddPTM_PC-9_AZD4547_30min_R2 3 ALSSGGSITSPPLSPALPK 19 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1;C9JW88;C9JHT0;C9JRZ2;C9JXQ0;C9JPV7;F8WCD5;C9J0V6 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 ALSSGGS(0.038)IT(0.947)S(0.015)PPLSPALPK;ALSS(0.001)GGS(0.127)IT(0.87)S(0.002)PPLSPALPK;ALS(0.023)S(0.145)GGS(0.218)IT(0.613)S(0.001)PPLSPALPK 188.0 1.1991e-10 476056600.0 113599.0 187553.0 134140.0 225735.0 169138.0 152105.0 137721.0 198687.0 143334.0 176643.0 True False 149721.11899401344 248175.83945118636 132361.21595448095 173695.2833209839 145656.10823439684 142593.85030478876 149977.90219907122 167984.48952305195 150910.3426178395 170458.78233594508 0.8783420657020694 1.4559287356756676 0.7764998326317951 1.018987000497635 0.8544945953405533 0.8365297953599169 0.8798484897275075 0.9854845096334389 0.8853186708820965 1.0 17.379063406012726 -5.2863086928585625 24.99871931992139 0.903101182908051 1.1671355834309842 0.3336931796908439 0.1483537482305752 680.1218417157684 683659.7205916881 0.03542975697208361 0.07380581814356693 5.1723905209843905e-06 5.2863086928585625 0.26403440052293325 ALSSGGSIT(ph)SPPLSPALPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALSSGGSITSPPLSPALPK 19 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1;C9JW88;C9JHT0;C9JRZ2;C9JXQ0;C9JPV7;F8WCD5;C9J0V6 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 ALS(0.008)S(0.055)GGS(0.248)IT(0.344)S(0.344)PPLSPALPK 114.54 0.00019311 7599900.0 16459.0 33556.0 14116.0 26445.0 18907.0 18313.0 19681.0 22415.0 20773.0 17582.0 True False 19245.183619932053 36887.21791612178 14452.578975228107 24963.372385846767 15202.309075035135 17352.63404180597 17816.673201899208 21826.630000655652 21076.765826345025 20769.47742096458 0.926608947825817 1.776030141176689 0.6958566497508389 1.2019258780506867 0.7319543369776853 0.8354872725054858 0.8578296333982467 1.0508993345506126 1.014795191961367 1.0 14.3421772966628 -5.278789300879131 24.97582663845293 0.9230121961653781 1.3513196525675721 0.33958363346402776 0.23859373551848 723.2979807607948 1041212.4484130193 0.057873604128806114 0.12091964828186193 5.262725269791459e-06 5.278789300879131 0.42830745640219403 ALSSGGSIT(ph)SPPLSPALPK ddPTM_PC-9_Lapatinib_30min_R1 1 ALSSGGSITSPPLSPALPK 19 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1;C9JW88;C9JHT0;C9JRZ2;C9JXQ0;C9JPV7;F8WCD5;C9J0V6 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 ALSS(0.001)GGS(0.095)IT(0.816)S(0.087)PPLSPALPK 136.34 0.00023783 285980000.0 140320.0 109780.0 126280.0 121500.0 133970.0 130250.0 138930.0 154880.0 160630.0 119350.0 True False 138319.01106846356 109525.8111548631 115897.74585489632 130435.51531211815 126090.14799515392 124679.51112757981 146123.1156102893 162076.29021723804 142538.15789111203 139979.48847612133 0.9881377091334276 0.7824418587838087 0.8279623473168138 0.9318187738224857 0.9007758877234592 0.8906984336412153 1.0438894812450754 1.157857425981994 1.0182788881631553 1.0 17.094855915594493 -7.285535320031325 4.1136790315502445 1.0717865593266516 0.8810296607568457 0.6122818860611947 0.06521719085599231 0.13598622384532638 5.41179907333218 0.027713162408989116 0.019021383511073433 5.1816094962237093e-08 7.285535320031325 -0.19075689856980582 ALSSGGSITS(ph)PPLS(ph)PALPK ddPTM_PC-9_Lapatinib_30min_R1 1 ALSSGGSITSPPLSPALPK 19 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1;C9JW88;C9JHT0;C9JRZ2;C9JXQ0;C9JPV7;F8WCD5;C9J0V6 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 2 ALSS(0.006)GGS(0.035)IT(0.258)S(0.849)PPLS(0.851)PALPK 92.24700000000001 0.010776 1841600.0 8043.9 8610.8 6268.7 6053.2 12192.0 13177.0 16592.0 15697.0 16846.0 13719.0 True False 7929.192510929399 8590.862221645973 5753.311683881773 6498.372520883252 11474.890530394248 12613.450427087271 17451.052574720496 16426.339924715827 14948.626083755673 16090.31087058157 0.49279299664909487 0.5339152419579986 0.35756373696923016 0.40386867433148443 0.7131553033803814 0.7839158937661574 1.0845690126861882 1.0208839379696901 0.9290452001823485 1.0 13.973904579266113 -6.707528696369282 1.6711515673177086 1.0063923817956961 0.4476739254476542 0.9171460332322294 0.07427204358508199 0.09750504087358565 0.5636222700780379 0.03228059912624598 0.030663940904417736 1.9609715983649875e-07 6.707528696369282 -0.5587184563480418 down ALSSGGSITS(ph)PPLSPALPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALSSGGSITSPPLSPALPK 19 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1;C9JW88;C9JHT0;C9JRZ2;C9JXQ0;C9JPV7;F8WCD5;C9J0V6 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 ALSS(0.006)GGS(0.216)IT(0.036)S(0.73)PPLS(0.012)PALPK;ALSSGGSIT(0.231)S(0.769)PPLSPALPK 147.09 0.00015548 309221200.0 72201.0 77158.0 91186.0 88069.0 115882.0 100877.0 112817.0 108587.0 108516.0 97321.0 True False 84423.20326524782 84817.73632054256 93360.22006483095 83134.77945355028 93175.75396589753 95586.83253619082 102130.15703565156 105736.70630743701 110102.84120789758 114964.52690738786 0.7343413271578697 0.7377731079506752 0.8120784956566584 0.7231341848648782 0.8104739476808986 0.8314463174644544 0.88836234778685 0.9197333225457925 0.9577114277745281 1.0 16.81082925082847 -7.400015202654554 0.6296257907080702 0.9995050736107235 0.7417741543945369 0.9319058349855486 0.024076083010603367 0.1776434064752627 0.14094168085273298 0.02151814854996994 0.014034278606769405 3.980932348943729e-08 7.400015202654554 -0.2577309192161866 ALSSGGSITS(ph)PPLSPALPK ddPTM_PC-9_Lapatinib_30min_R1 1 ALSSGGSITSPPLSPALPK 19 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1;C9JW88;C9JHT0;C9JRZ2;C9JXQ0;C9JPV7;F8WCD5;C9J0V6 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 ALSSGGS(0.002)IT(0.055)S(0.943)PPLSPALPK 153.92 3.1732e-05 301390000.0 169290.0 156410.0 166920.0 158540.0 166460.0 194370.0 173600.0 160940.0 209570.0 124880.0 True False 166875.89355601656 156047.84225480142 153196.48192983333 170199.56047393582 156669.15007295168 186057.24819860034 182588.15856867653 168417.85994035605 185966.01973006496 146465.3416078593 1.1393541415606956 1.0654250387275779 1.045957222699113 1.162046656263716 1.069667051283789 1.2703158723839452 1.2466304762906373 1.1498820000111125 1.2696930051067183 1.0 17.16019979160326 -6.745886464249252 24.999779947078164 1.2003797932386397 1.0955988332413222 0.23335959651148497 0.08056901183799524 301.8101522638275 485129.4460359561 0.02513791507388798 0.02505151884639417 1.7952028777104948e-07 6.745886464249252 -0.10478095999731751 ALSSGGSITSPPLS(ph)PALPK ddPTM_PC-9_AZD4547_30min_R2 2 ALSSGGSITSPPLSPALPK 19 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1;C9JW88;C9JHT0;C9JRZ2;C9JXQ0;C9JPV7;F8WCD5;C9J0V6 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 ALSSGGSIT(0.002)S(0.01)PPLS(0.988)PALPK;ALSSGGSITSPPLS(1)PALPK 149.95 9.504899999999999e-05 29007000.0 105979.0 96469.0 132546.0 158017.0 154067.0 125452.0 107580.0 124691.0 114349.0 122664.0 True False 139678.11749985995 127650.71769588583 130788.35343598199 121588.62198831337 132677.4564400007 117607.4666081742 117154.4115899253 105422.87106413029 120393.25469188986 118369.570696016 1.1800170996528005 1.0784082171228337 1.1049153314229598 1.027194922422792 1.120874694905574 0.9935616553869325 0.9897341935182704 0.8906247648296872 1.0170963194677023 1.0 16.852938728983133 -6.862775678982752 4.3470131813664485 0.9684194804399887 1.096913065005335 0.626520862443785 0.04777718276665107 0.14420900688404018 4.841641051979406 0.01703697257929304 0.015064037905297572 1.3715900344897514e-07 6.862775678982752 0.1284935845653462 ALSSGGSITSPPLS(ph)PALPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALSSGGSITSPPLSPALPK 19 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1;C9JW88;C9JHT0;C9JRZ2;C9JXQ0;C9JPV7;F8WCD5;C9J0V6 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 ALSSGGSITSPPLS(1)PALPK;ALSSGGSITS(0.001)PPLS(0.999)PALPK 139.46 5.8318e-05 14951000.0 38828.0 36887.0 40344.0 49292.0 94007.0 105128.0 100434.0 118736.0 97550.0 87405.0 True False 45400.81351204337 40548.897582309684 41305.95396547202 46530.32904682017 75587.0031848959 99614.9026127329 90920.16444080793 115619.305811191 98976.48420353112 103250.83460240079 0.43971376780510507 0.3927222258149847 0.40005443175867145 0.4506532971476653 0.7320715951204365 0.9647854469780397 0.8805755884775565 1.1197905204003322 0.9586022678138207 1.0 16.65579391779464 -6.480771024242301 1.747840265151494 0.9988566927221603 0.4017016501228712 0.9567325797897397 0.05657159574775179 0.06455423032552757 0.39671090314243546 0.021118513222710165 0.023790226710994743 3.3054376973290347e-07 6.480771024242301 -0.5971550425992891 down ALSSGGSITSPPLS(ph)PALPK ddPTM_PC-9_Lapatinib_30min_R1 2 ALSSGGSITSPPLSPALPK 19 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1;C9JW88;C9JHT0;C9JRZ2;C9JXQ0;C9JPV7;F8WCD5;C9J0V6 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 ALSSGGSITS(0.021)PPLS(0.979)PALPK;ALSSGGSITS(0.003)PPLS(0.997)PALPK 256.33 1.6994999999999996e-65 17274900.0 53172.0 36065.0 40851.0 43095.0 71519.0 75811.0 77974.0 71978.0 95753.0 105488.0 True False 52413.757529449416 35981.49370832702 37492.388469420184 46264.350060705685 67312.39303176399 72568.74025407244 82011.11219028776 75322.36064860757 84968.28881620894 123721.46024607532 0.423643217799089 0.2908266167951927 0.30303868378897114 0.37393957336656375 0.5440640039155961 0.5865493351738423 0.662868931769574 0.6088059460242019 0.686770820900526 1.0 16.91673624075984 -7.768059188403146 0.23356551535816494 1.0954126850008044 0.16993394489927288 0.9049092535547165 0.0627330412492904 0.6778811447511658 0.16102678119052255 0.21681784853110314 0.2480473275109993 1.7058498891311634e-08 7.768059188403146 -0.9254787401015314 down ALSSLHGDDQDS(ph)EDEVLTIPEVK ddPTM_PC-9_AZD4547_30min_R2 6 ALSSLHGDDQDSEDEVLTIPEVK 23 0 P11717 P11717 IGF2R Cation-independent mannose-6-phosphate receptor 1 ALSSLHGDDQDS(1)EDEVLTIPEVK;ALSSLHGDDQDS(1)EDEVLTIPEVK;ALSSLHGDDQDS(1)EDEVLTIPEVK;ALSSLHGDDQDS(0.997)EDEVLT(0.003)IPEVK;ALSSLHGDDQDS(0.874)EDEVLT(0.126)IPEVK;ALS(0.001)S(0.002)LHGDDQDS(0.991)EDEVLT(0.007)IPEVK 119.66 2.0307000000000003e-07 3194500.0 20286.2 22178.699999999997 69862.0 101073.0 74606.0 61345.399999999994 45775.5 79163.0 53177.8 64948.0 True False 26736.789620827254 29347.531046882872 68935.58423298011 77772.18141228353 64248.24469330009 57509.46244033651 49849.430821106274 66930.17733476947 55988.66994336961 62674.190288632664 0.42659968158657735 0.4682554479240825 1.0999038665758891 1.2408964687715993 1.0251148741997056 0.9175940235603987 0.7953741498938449 1.0679065341975182 0.8933289713919828 1.0 15.935583832010815 -5.25402589471946 24.420001110588952 1.0059729569069813 0.44742743008383024 0.7878249009656486 0.11574493754937497 191.0585501307364 629340.6134427564 0.03274540750415416 0.08292103743938323 5.5715252783627465e-06 5.25402589471946 -0.5585455268231511 ALSSLHGDDQDS(ph)EDEVLTIPEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALSSLHGDDQDSEDEVLTIPEVK 23 0 P11717 P11717 IGF2R Cation-independent mannose-6-phosphate receptor 1 ALSSLHGDDQDS(1)EDEVLTIPEVK 110.33 0.00039516 0.0 3214.5 4365.3 7272.1 10283.0 12607.0 9594.8 8636.2 8024.5 8282.2 6850.1 True False 3758.651360731004 4798.658134737348 7445.494443592827 9706.87684793581 10136.748850106736 9091.631797319942 7818.116615326554 7813.865377660548 8403.311506616988 8091.968904638235 0.4644915724498871 0.5930149004881624 0.9201091268807453 1.1995692225623762 1.25269251149698 1.1235376586912873 0.9661575208037797 0.9656321557515772 1.038475506474116 1.0 12.982275060661792 -5.294976413142796 2.5875558080800154 1.0806366196533526 0.48756332794949814 0.8475368846728054 0.09230605238392839 0.11570556890617532 1.491105469601856 0.02915607158264409 0.08914564393877328 5.0701824406591695e-06 5.294976413142796 -0.5930732917038544 down ALSSLHGDDQDS(ph)EDEVLTIPEVK ddPTM_PC-9_Lapatinib_30min_R1 3 ALSSLHGDDQDSEDEVLTIPEVK 23 0 P11717 P11717 IGF2R Cation-independent mannose-6-phosphate receptor 1 ALS(0.001)S(0.001)LHGDDQDS(0.998)EDEVLTIPEVK;ALSSLHGDDQDS(0.919)EDEVLT(0.081)IPEVK;ALSSLHGDDQDS(0.989)EDEVLT(0.011)IPEVK 75.611 0.0025947 0.0 21486.4 17504.2 31438.1 17249.699999999997 22409.4 30653.7 16440.9 20999.3 37878.0 14666.099999999999 True False 21179.99999587681 17463.67010035484 28853.380772575423 18518.30048131233 21091.323150575536 29342.71270826481 17292.12935605847 21975.004139713634 33611.78076697719 17201.115843650146 1.2313154674611113 1.0152637921336725 1.6774133163707954 1.0765755343801389 1.2261601713682704 1.7058610019824254 1.0052911400187985 1.2775336402275197 1.9540465323582537 1.0 14.070214535749173 -5.212006819580241 24.998840553338407 1.3592887154262248 1.123289609057309 0.08896129711262102 0.30937491856997573 964.0139330130692 487513.8693045241 0.07577292165923734 0.20047557510790365 6.137523675420406e-06 5.212006819580241 -0.23599910636891575 ALSSQHQAR ddPTM_PC-9_AZD4547_30min_R2 1 ALSSQHQAR 9 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 96.03399999999999 0.0043933999999999996 402470.0 879.7 709.19 1931.5 3007.3 1910.3 2278.3 1149.3 2262.1 2479.9 5211.7 False True 1159.4263011032988 938.4217985336767 1905.8870479803193 2314.013447321838 1645.0878191782344 2135.8375408395523 1251.5854735108833 1912.5444228867307 2610.982451183808 5029.239969318018 0.23053708078688498 0.18659316402850626 0.37896124655168606 0.46011195755998624 0.3271046578040526 0.42468395898181394 0.24886175269950433 0.38028498034586294 0.5191604431509889 1.0 12.296124677666265 -14.522878744734165 0.2107282359208153 4.172544276547418 0.25713423050578693 0.8576491527194813 0.08259441070333472 55.408408088566254 0.551019920314112 74.13130156147932 0.18884990087224626 3.0000000037728297e-15 14.522878744734165 -3.915410046041631 ALSSS(ph)VIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALSSSVIR 8 0 H0YJ17;Q8NEJ9-2;Q8NEJ9 H0YJ17 NGDN Neuroguidin 1 ALS(0.183)S(0.183)S(0.635)VIR 85.86200000000001 0.012908000000000001 4686200.0 29879.0 34527.0 35734.0 29046.0 50131.0 41818.0 32416.0 32977.0 32112.0 31396.0 True False 34936.92456285009 37954.61237900633 36586.03408194968 27418.64678840256 40308.1904183946 39624.99046361834 29345.321808483528 32111.3886920197 32581.577250064547 37087.84626940075 0.9420046747679367 1.0233706239858071 0.9864696325635633 0.7392892698388975 1.0868301741115336 1.0684090463433262 0.7912382292388552 0.8658197205296642 0.8784974197044683 1.0 15.178658870990487 -7.266875022883304 24.99759362953458 0.8727071596467909 0.9715945432312013 0.15610866457352435 0.10164509731420344 856.023823159136 3936686.776988369 0.04273002203860215 0.029727919776791175 5.4090995845077624e-08 7.266875022883304 0.0988873835844104 ALST(ph)TSSSTTNGNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALSTTSSSTTNGNR 14 0 A0A0A0MT72;Q9BSQ5-4;Q9BSQ5;Q9BSQ5-2;C9JUH3;Q9BSQ5-3 A0A0A0MT72 CCM2 Cerebral cavernous malformations 2 protein 1 ALS(0.305)T(0.663)T(0.014)S(0.006)S(0.006)S(0.006)T(0.002)TNGNR 160.46 0.0011805 7898600.0 19908.0 19891.0 24237.0 24937.0 28235.0 25120.0 19686.0 24340.0 22184.0 17458.0 True False 23278.03119907694 21865.64702496061 24814.901999334368 23539.860736844807 22702.554436643422 23802.66297876734 17821.199565702347 23701.100790361743 22508.399031995265 20622.997202548042 1.1287414225222734 1.0602555394935045 1.2032636069149252 1.1414374208389253 1.10083680920242 1.1541805851492062 0.8641420735634138 1.1492558796174104 1.091422299626471 1.0 14.331966398726072 ALSTGLDYS(ph)PPSAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALSTGLDYSPPSAPR 15 0 P54253 P54253 ATXN1 Ataxin-1 1 ALST(0.006)GLDYS(0.81)PPS(0.183)APR 100.18 0.0019173999999999999 7960400.0 72296.0 100750.0 81592.0 83118.0 91480.0 73388.0 88321.0 53299.0 74876.0 70683.0 True False 84534.28488891249 110751.79416644596 83537.46271938311 78461.16793219185 73555.15069467472 69539.40408780957 79954.59549133382 51899.95772495854 75970.91984852498 83497.26837367997 1.0124197657651686 1.3264121847770194 1.0004813851576948 0.9396854467268345 0.8809288271023343 0.8328344800047351 0.9575713918389351 0.6215767142547439 0.9098611407085571 1.0 16.349441379912086 -5.664335281264752 2.118998262108412 0.8552258883180731 1.170008417331176 0.46907523045527555 0.12164955420064463 0.2415965186570077 2.193225824875021 0.034671745192391294 0.07380899072653835 2.1660312534936752e-06 5.664335281264752 0.3147825290131029 ALSTGLDYSPPS(ph)APR ddPTM_PC-9_AZD4547_30min_R2 1 ALSTGLDYSPPSAPR 15 0 P54253 P54253 ATXN1 Ataxin-1 1 ALSTGLDYS(0.286)PPS(0.714)APR 94.45 0.0030302 7013400.0 8221.3 10839.0 9563.9 14650.0 12624.0 13151.0 12992.0 13507.0 14390.0 10818.0 True False 10835.50238633688 14342.494781802505 9437.076437058746 11272.668840243716 10871.375506101667 12328.66589105076 14148.262831161053 11419.803509982352 15150.62602223275 10439.265112742934 1.0379564336487892 1.3738988929685292 0.9039981584085988 1.0798335628514182 1.041392798122472 1.1809898261901102 1.3552929902978175 1.0939279141443108 1.4513115490992543 1.0 13.349732534415264 -6.968992117471294 7.061785964788023 1.2379340542310089 1.0939687970478194 0.1409273752742689 0.1603829511025137 0.3500240764001267 57.55941674978061 0.054706462261318506 0.047700883103272626 1.0740089056333618e-07 6.968992117471294 -0.14396525718318953 ALSVGNIDDALQCYSEAIK ddPTM_PC-9_Lapatinib_30min_R1 1 ALSVGNIDDALQCYSEAIK 19 0 P31948-2;P31948;P31948-3;F5H783;F5GXD8 P31948-2 STIP1 Stress-induced-phosphoprotein 1 0 163.9 5.041e-07 10602000.0 39454.0 31620.0 35944.0 33055.0 40961.0 29138.0 37233.0 33105.0 32533.0 32621.0 False True 38891.378725022536 31546.78583272702 32988.82306785242 35485.974968247494 38551.75451242445 27891.835663995527 39160.74255753184 34643.17915574422 28868.790952322393 38259.496385249746 1.0165156993550077 0.8245478590483828 0.8622388213288312 0.9275076339459729 1.0076388388449196 0.7290173237813115 1.023556143112996 0.9054792255211249 0.7545522989019853 1.0 15.223530262975121 ALSYAS(ph)LDKEDLLSPINQNTLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALSYASLDKEDLLSPINQNTLQR 23 1 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 ALS(0.006)Y(0.016)AS(0.977)LDKEDLLSPINQNTLQR 62.325 0.0016547 13627000.0 7698.6 9429.6 16547.0 17147.0 18624.0 21447.0 22858.0 17838.0 17683.0 16741.0 True False 9001.820925718996 10365.70836994463 16941.54323484695 16186.309181324055 14974.760893502633 20322.281564714285 20692.724762411046 17369.771400923277 17941.580422050687 19776.010778316922 0.4551889168461059 0.5241556796333231 0.8566714199722334 0.8184820165587321 0.7572184836145751 1.0276229009237956 1.0463548485268443 0.8783253405165047 0.9072396158745238 1.0 14.271463814201914 -4.668170704291171 0.6327132284521045 0.959440638116063 3.039282565055357e-15 0.8123078998942896 0.08255909886556044 1.6933607164482143 0.4640775821962885 0.041550187814516304 1.2201685147568582 2.146986411296159e-05 4.668170704291171 -0.95944063811606 down ALSYAS(ph)LDKEDLLSPINQNTLQR ddPTM_PC-9_Lapatinib_30min_R1 1 ALSYASLDKEDLLSPINQNTLQR 23 1 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 ALS(0.015)Y(0.049)AS(0.913)LDKEDLLS(0.023)PINQNT(0.001)LQR 44.341 0.030035000000000003 12622000.0 12730.0 13606.0 9505.0 15357.0 11045.0 14403.0 12823.0 11330.0 11839.0 10923.0 True False 12548.467865603916 13574.496142950144 8723.535590361036 16486.405009450224 10395.354815305487 13787.017265032864 13486.912196579126 11856.43316219853 10505.567149803128 12811.025996017384 0.9795053003174694 1.0595947699403703 0.6809396525362572 1.2868918550766675 0.8114381173324551 1.0761836928064068 1.052758163223762 0.9254866211249893 0.8200410453517959 1.0 13.645098400903665 -7.981425783099053 19.806437121163864 0.8976017122286184 0.9905441439844606 0.04745316888840845 0.15759172050020326 60.73990762476554 64768.40765943606 0.08105068271437833 0.038895260037036083 1.0436964755419855e-08 7.981425783099053 0.09294243175584216 ALT(ph)TPTHYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALTTPTHYK 9 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;P52948-4;P52948-3;H0YEN4;H0YCR0 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 ALT(0.899)T(0.101)PTHYK 79.20100000000001 0.042968 12341000.0 92749.0 101040.0 105530.0 102200.0 115790.0 114210.0 124240.0 121680.0 130060.0 87947.0 True False 108449.57382374872 111070.58344990302 108046.23542475347 96474.06533687055 93101.78070546965 108220.62654478566 112471.08778029338 118486.02893061683 131961.8814506541 103891.0949119313 1.0438774749239255 1.0691059088756143 1.039995155661267 0.9286076484096334 0.8961478438974219 1.0416737511191358 1.0825864129705762 1.1404830128227803 1.2701943469025758 1.0 16.664712472500035 -7.425420255512849 2.257659748367555 1.152131399749254 0.9981908536427986 0.36917426841887546 0.07910503684417372 0.3244475031723944 3.2388001440872425 0.04375871093941257 0.025093956967919304 3.7547389208338e-08 7.425420255512849 -0.15394054610645536 ALTHNGT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 ALTHNGTPR 9 0 Q9HB90 Q9HB90 RRAGC Ras-related GTP-binding protein C 1 ALTHNGT(1)PR 91.31299999999999 0.033788 0.0 17663.0 14230.0 20628.0 30070.0 28496.0 25813.0 19395.0 25967.0 18947.0 25260.0 True False 23279.466586776816 18829.56921718329 20354.459241904242 23137.826076868852 24539.82227676434 24198.909029404094 21121.117426906447 21954.396812298182 19948.49973893286 24375.655088545616 0.9550293726348339 0.7724743867922347 0.8350322962794555 0.9492186360866899 1.0067348831291867 0.9927490744966859 0.8664840944862027 0.9006689966914896 0.81837799503107 1.0 14.57315337093668 -5.758936783685803 24.998436250672214 0.9320557574690356 0.8460082389941721 0.2068565355141343 0.07056369599113924 101.11828805577416 1010043.4124186904 0.020201496573842834 0.03300594573277907 1.7420604308957014e-06 5.758936783685803 -0.08604751847486347 ALTQTGGPHVK ddPTM_PC-9_AZD4547_30min_R2 2 ALTQTGGPHVK 11 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 92.943 0.0061868 11131300.0 71233.0 58847.0 69996.0 100592.0 90271.0 67887.0 63628.0 88222.0 75748.0 83405.0 False True 93883.61226155654 77868.1419341943 69067.80730542609 77402.06853090765 77738.42984088269 63642.015158220864 69290.76873623121 74589.31703988017 79751.88463739307 80485.01633650613 1.1664731714662413 0.9674861915742088 0.8581449125468903 0.9616953819986972 0.9658745612457849 0.7907312199842883 0.8609151353902693 0.9267478648202522 0.9908910784580344 1.0 16.296432605397 -4.788304631368128 3.3509031085416057 0.9130363429155514 1.1980293184265638 0.5762639221294457 0.0631105309529146 0.2183842386182967 3.916548829897075 0.016455845863717844 0.16042979087713327 1.6281535805329947e-05 4.788304631368128 0.28499297551101244 ALTQTGGPHVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALTQTGGPHVK 11 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 118.61 0.0008787 6093600.0 22203.0 21948.0 27046.0 25630.0 35055.0 21866.0 29305.0 35937.0 31227.0 23243.0 False True 25961.529370760745 24126.852390721222 27690.879212526197 24194.034193581127 28186.224394423076 20719.30846710695 26529.01825017307 34993.69182839895 31683.63579932006 27456.771908513227 0.9455419397904942 0.8787213759546317 1.0085263957756223 0.8811681968366989 1.0265673069048469 0.7546156021597985 0.966210388408679 1.2745013122809543 1.1539461341227901 1.0 14.744874397411035 -7.624750797391745 6.558841660957055 1.1585610379499949 0.9170299517703373 0.5350447322693308 0.09442568357097642 0.14696297435375044 8.198690508063793 0.0427710505286242 0.024411111764100078 2.3727348145795814e-08 7.624750797391745 -0.24153108617965757 ALTQTGGPHVK ddPTM_PC-9_Lapatinib_30min_R1 2 ALTQTGGPHVK 11 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 112.64 0.0013949000000000001 19340800.0 110976.0 97354.0 99001.0 79476.0 79538.0 85974.0 72991.0 72824.0 86063.0 66023.0 False True 109393.4618894943 97128.58279441214 90861.51993491164 85320.930164164 74859.73121772453 82297.09243518271 76770.11683229402 76207.66889708256 76369.67865643262 77434.98757988244 1.4127136234979478 1.2543242509623143 1.173391031298072 1.1018395279801185 0.9667429873414617 1.0627895090741055 0.9914138199234225 0.984150334091114 0.9862425376855541 1.0 16.240697948539953 -4.703808125695988 0.6368340551322208 0.9870747589560587 1.722307825101068 0.954817313405884 0.02959500398568709 0.689769452471859 0.19756362123119034 0.013901685506770765 0.3797650299505391 1.977843271938044e-05 4.703808125695988 0.7352330661450093 ALTSELANAR ddPTM_PC-9_Lapatinib_30min_R1 1 ALTSELANAR 10 0 P26038 P26038 MSN Moesin 0 114.89 0.0053886 4524000.0 16827.0 18088.0 19675.0 15312.0 20259.0 22713.0 14627.0 14646.0 16036.0 14450.0 False True 16587.04389430613 18046.118347323416 18057.397447696305 16438.09555933462 19067.40545072647 21741.617936589002 15384.314489539332 15326.506627851679 14229.856813433813 16947.66324658529 0.9787215885144628 1.0648145460973477 1.0654800714980346 0.9699328644995739 1.1250757802594573 1.2828681818993322 0.9077543178490434 0.9043433542933862 0.8396353294487914 1.0 14.048798747013397 -7.454706102482444 24.99999055481327 0.9044008154669235 1.078192040077262 0.4598525112229208 0.08909498032276471 159.68314572300886 58558.174754082305 0.03863756967790524 0.02604942597198753 3.509893165112091e-08 7.454706102482444 0.17379122461033847 ALTVPELTQQVFDAK ddPTM_PC-9_AZD4547_30min_R2 1 ALTVPELTQQVFDAK 15 0 Q5JP53;P07437;Q5ST81 Q5JP53 TUBB Tubulin beta chain 0 143.86 8.306499999999999e-07 0.0 14648.0 14610.0 16043.0 29975.0 22858.0 21901.0 17189.0 23261.0 19703.0 18485.0 False True 19305.75930267264 19332.396785878293 15830.259337690017 23064.726859133487 19684.561257800367 20531.527007824716 18718.78770049471 19666.546934604237 20744.460355528274 17837.84577639611 1.082292085304322 1.0837853980921757 0.8874535376148041 1.2930219908983538 1.1035279430349108 1.1510093351627142 1.0493861161903477 1.1025180496082074 1.162946502372968 1.0 14.12265377533637 -5.750223050018824 24.999975413762076 1.1247363208197902 1.0244379380764657 0.22832861044949093 0.08847860274734402 342.0499791704448 762385.0719248053 0.023445804611197586 0.04013897731593258 1.7773663350794266e-06 5.750223050018824 -0.10029838274332459 ALTVPELTQQVFDAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALTVPELTQQVFDAK 15 0 Q5JP53;P07437;Q5ST81 Q5JP53 TUBB Tubulin beta chain 0 ; 269.14 3.2106999999999994e-61 54592000.0 158906.0 176235.0 178509.0 209636.0 210160.0 178091.0 212546.0 187453.0 169083.0 158773.0 False True 185805.64726343757 193730.44610346077 182765.33155915214 197890.77456908164 168980.65664618314 168751.5944487124 192412.10418021792 182532.55737287077 171555.51900139128 187557.28805362398 0.9906607692595469 1.0329134533448352 0.9744507049328748 1.055095094531881 0.9009548943673698 0.899733602463185 1.0258844440382713 0.9732096218019712 0.9146832990693612 1.0 17.51697179840412 -6.256780757115805 24.99935054462163 0.9521112629806013 1.0119088710183595 0.31743336083503104 0.04370702657367173 536.7120588078701 2880135.366626405 0.013367211950280476 0.016675199987954924 5.536295249263818e-07 6.256780757115805 0.05979760803775813 ALTVPELTQQVFDAK ddPTM_PC-9_Lapatinib_30min_R1 2 ALTVPELTQQVFDAK 15 0 Q5JP53;P07437;Q5ST81 Q5JP53 TUBB Tubulin beta chain 0 ; 222.74 6.498799999999999e-19 58256000.0 95583.0 83186.0 95919.0 87586.0 95298.0 88293.0 88323.0 73711.0 77883.0 82518.0 False True 94219.96889222467 82993.3879279328 88032.91007804747 94027.36661833069 89692.75900307675 84516.91421103566 92895.93277224187 77135.88215523511 69110.99639565144 96781.12635167631 0.9735366020628331 0.8575369088633809 0.9096082407447894 0.9715465211332713 0.926758784322861 0.8732788860497879 0.9598558755627961 0.7970136850334256 0.7140958056689779 1.0 16.562438109139464 -7.7677658091009185 24.99974250234271 0.8166660339442068 0.9213498016515098 0.20364334657441863 0.07602245210944303 194.62431539527063 769067.5255926452 0.03812104700631341 0.019014452047219514 1.7070026325979516e-08 7.7677658091009185 0.10468376770730303 ALVADSHPESER ddPTM_PC-9_AZD4547_30min_R2 2 ALVADSHPESER 12 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 ; 116.84 0.0005526 11535300.0 48323.0 37839.0 68686.0 88197.0 89126.0 78924.0 56330.0 77340.0 63826.0 64186.0 False True 63688.70881915959 50069.71676802519 67775.17876136488 67864.54428006662 76752.39332674403 73988.86980345892 61343.26087433048 65388.88009639704 67199.71205663844 61938.86767669786 1.0282510999651362 0.8083731370320483 1.0942269580246573 1.095669759968797 1.2391636496709673 1.1945466970700598 0.9903839572031529 1.0557002823769268 1.0849360761226794 1.0 15.918557388455717 -5.330718634101212 9.76112284008152 1.101589187519867 0.9185261891599189 0.389964155874875 0.08768957831331942 0.4548863581393059 62.1231442271435 0.023664660515568287 0.04936070010677232 4.669618123825843e-06 5.330718634101212 -0.183062998359948 ALVADSHPESER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALVADSHPESER 12 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 ; 129.74 0.00013968 7351800.0 38632.0 41378.0 64804.0 58311.0 68755.0 59054.0 57997.0 61280.0 44429.0 37315.0 False True 45171.63458321979 45485.7343823247 66349.17313053862 55044.0237168127 55282.95131189721 55957.10428137448 52503.104298081795 59671.46493152699 45078.69007358988 44079.91411462255 1.0247668465450817 1.0318925364520117 1.5052019601945805 1.248732553645177 1.2541528816989753 1.2694467628922155 1.191089078838859 1.353711007157618 1.0226583009297654 1.0 15.427833792511858 -8.336486912612608 7.952583637375459 1.0073412223541676 1.2377866872957524 0.31163738911055217 0.13286082214679898 0.4447561939596068 42.243370349224065 0.13143558157061289 0.03405633754412769 4.608006546272635e-09 8.336486912612608 0.2304454649415848 ALVADSHPESER ddPTM_PC-9_Lapatinib_30min_R1 2 ALVADSHPESER 12 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 ; 161.93 6.9507e-05 22968200.0 91146.0 74945.0 90456.0 70712.0 83945.0 92911.0 74825.0 76964.0 90815.0 67478.0 False True 89846.24132587071 74771.46945710704 83019.05685025756 75912.3963683171 79007.52014221989 88937.41311611937 78699.07237846313 80540.02841089573 80586.4583756543 79141.48239121692 1.1352610364528855 0.9447822709144141 1.0489954742049534 0.9591985653372322 0.9983073068010677 1.123777448045244 0.9944098846851661 1.0176714660557586 1.0182581364510521 1.0 16.272146468090135 -9.202051332175625 0.003019535334157535 2.3168410540386892e-05 2.0279284443862573 0.028075689784270552 0.058837617104285374 201711.32187317123 224.83131952693168 76157.27810595042 74833.10777911887 6.279841287733606e-10 9.202051332175625 2.027905275975717 ALVAT(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALVATPGK 8 0 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 1 ALVAT(1)PGK 87.149 0.0292 47177000.0 192280.0 227860.0 238000.0 238900.0 317380.0 228280.0 275840.0 238440.0 205720.0 159510.0 True False 224829.2062968918 250480.434925722 243674.82262002648 225515.20752425067 255191.6673313935 216308.5949360276 249710.43829134107 232181.20264806258 208728.26581599624 188427.90031953456 1.1931842679116424 1.3293171260782466 1.2931992672359274 1.196824924237991 1.3543199648175321 1.1479647895519356 1.3252307002725396 1.2322018249650477 1.107735454579903 1.0 17.523653073530156 -8.417875415154331 2.2348075549017667 1.0022915023738768 1.264307013211992 0.6454158589234527 0.06357348904502531 0.1638758932751749 1.699727008182402 0.0563742683114532 0.01569489207612264 3.820538538439398e-09 8.417875415154331 0.26201551083811525 ALVAT(ph)PGKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ALVATPGKK 9 1 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 1 ALVAT(1)PGKK;ALVAT(1)PGKK;ALVAT(1)PGKK 93.556 0.021021 1420040000.0 249086.0 229092.0 233868.0 283343.0 331417.0 256371.0 309458.0 304518.0 213042.0 228946.0 True False 291251.34012724913 251834.73974371678 239444.30006932918 267468.2103204005 266478.2179468414 242926.4534446484 280143.8979580977 296524.7251634909 216157.3362141332 270452.0974644612 1.076905458888227 0.9311620878695871 0.885348282798189 0.9889670401078962 0.9853065309721177 0.898223588288385 1.0358355530776018 1.0964038657620534 0.79924444380594 1.0 18.04501356065014 -7.279720553276216 24.64437023890205 0.9909046075904029 0.9585692136842602 0.011235471172973854 0.08681109377431222 3245.797422206734 4375550.985039703 0.03562217038258575 0.02406068633251008 5.251452562025689e-08 7.279720553276216 -0.032335393906142706 ALVAT(ph)PGKK ddPTM_PC-9_Lapatinib_30min_R1 1 ALVATPGKK 9 1 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 1 ALVAT(1)PGKK 85.29 0.042787 210000000.0 141980.0 120920.0 125230.0 121470.0 124280.0 108750.0 106530.0 92382.0 98736.0 86818.0 True False 139955.33916405687 120640.01716930293 114934.07280177945 130403.30901204118 116970.09474388111 104099.0160086318 112045.60214470676 96674.40497707184 87615.31194382643 101824.37562228659 1.374477754552756 1.1847852386231388 1.1287481224350715 1.2806688792845338 1.1487435501473335 1.0223388591625928 1.1003809398285476 0.9494230078628878 0.8604551848059632 1.0 16.63572344233186 -6.932709341604319 0.7338959299082416 0.9245591784929459 1.2556928514970396 0.7212528596795964 0.07727189649127007 0.38120953034190197 0.43672572101567403 0.059890787540862286 0.05027991464181657 1.1675907840782962e-07 6.932709341604319 0.3311336730040937 ALVATPGKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALVATPGKK 9 1 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 0 80.219 0.039349 0.0 26377.0 20114.0 25845.0 29551.0 31992.0 28738.0 23301.0 25433.0 30258.0 23924.0 False True 30842.105130502947 22110.784991204946 26461.242817708302 27895.35327563466 25723.397256493576 27230.928689642336 21093.760595368803 24765.410698490967 30700.466007487958 28261.2318177202 1.091322038948228 0.7823715941971491 0.9363088979411266 0.9870536944587063 0.9102008512015614 0.9635435873877285 0.7463850383953439 0.8763032998074308 1.086310257298775 1.0 14.786536729106148 -8.258215329341734 24.939922692951367 1.0431551332779776 0.9068776875060671 0.2329412448004965 0.0951080237153714 355.32113197888333 2748677.1609970587 0.06908869264105687 0.023644525548799464 5.518037793320453e-09 8.258215329341734 -0.13627744577191048 ALVAYYQK ddPTM_PC-9_Lapatinib_30min_R1 1 ALVAYYQK 8 0 M0R210;P62249;M0R3H0;M0R1M5;M0QX76 M0R210 RPS16 40S ribosomal protein S16 0 158.53 0.00016299 4698800.0 52258.0 40850.0 62976.0 49235.0 50941.0 58586.0 50718.0 50427.0 53420.0 44655.0 False True 51512.79133705649 40755.41433481652 57798.35637438999 52855.90614314528 47944.750533859355 56080.41335063638 53343.929874920104 52770.02251281419 47403.2770624616 52373.557250952654 0.9835648758824663 0.7781677715632959 1.1035789701555676 1.0092097790853007 0.9154381151566187 1.0707772451262378 1.018527911314441 1.0075699509957254 0.9050994347266598 1.0 15.676550976584547 -5.262321042800498 24.99973096720467 1.0040045417891699 0.8808663310007246 0.31174852692719035 0.07304838384362469 85.12774863275254 2413907.5574457604 0.018207623281643347 0.041801545070283365 5.4661174260115615e-06 5.262321042800498 -0.12313821078844522 ALVEFESNPEET(ph)REPGSPPSVQR ddPTM_PC-9_AZD4547_30min_R2 1 ALVEFESNPEETREPGSPPSVQR 23 1 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 ALVEFES(0.143)NPEET(0.707)REPGS(0.148)PPS(0.002)VQR 61.61600000000001 0.0029679000000000003 540380000.0 40141.0 42935.0 58898.0 72409.0 63083.0 58735.0 50086.0 67936.0 54281.0 50086.0 True False 52905.00301533194 56812.89911031375 58116.97403673045 55716.223757898166 54325.01434184184 55062.29116499629 54543.55697056128 57438.05221397498 57150.18284314217 48332.504384991895 1.0946050424765468 1.1754594518374506 1.2024407751313795 1.1527692278076749 1.1239850910500455 1.139239355908363 1.1285067402279703 1.1883938758160133 1.1824378556491337 1.0 15.560706130578275 -10.628843545350595 4.969959717378959 0.9999944105753765 1.1551266695736409 0.6792133719951563 0.03178663977302048 2.0493854403574648e-06 3.6870406134991204e-07 0.03203981946536859 0.007770517682938599 2.3504794288952523e-11 10.628843545350595 0.15513225899826433 ALVEFESNPEET(ph)REPGSPPSVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALVEFESNPEETREPGSPPSVQR 23 1 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 ALVEFES(0.005)NPEET(0.469)REPGS(0.469)PPS(0.057)VQR;ALVEFES(0.003)NPEET(0.789)REPGS(0.19)PPS(0.018)VQR 60.325 0.0037700000000000003 212309500.0 39607.0 32523.5 43233.0 46643.3 52737.0 43750.0 57871.3 37654.0 36600.9 34279.4 True False 46311.68282609202 35752.21813967656 44263.83868206551 44030.0271206189 42403.563425722125 41455.67298252671 52389.311512071 36665.62239771081 37136.118920400084 40493.98386441893 1.143668229363448 0.8829019703119692 1.093096664192605 1.0873226815133643 1.0471571176522618 1.0237489381466562 1.2937554301270962 0.9054585125650725 0.9170774366073347 1.0 15.305419964245894 ALVEFESNPEET(ph)REPGSPPSVQR ddPTM_PC-9_Lapatinib_30min_R1 1 ALVEFESNPEETREPGSPPSVQR 23 1 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 ALVEFES(0.001)NPEET(0.499)REPGS(0.499)PPS(0.001)VQR 70.907 0.00057954 3029400.0 15448.0 16778.0 16404.0 19851.0 20327.0 17346.0 16479.0 17845.0 19175.0 18266.0 True False 15227.70868718376 16739.151571837247 15055.326441271181 21310.908760994753 19131.405824419628 16604.152015500946 17332.201987633736 18674.143846375347 17015.309578298416 21423.253762084918 0.7108027966383849 0.7813543058273603 0.7027562950272401 0.9947559319262234 0.8930205484602238 0.7750527627547938 0.8090368615391391 0.8716763594251509 0.79424487835794 1.0 14.38688999268756 -14.522878744794433 0.023779760726995124 2.0927035735236728 5.329086848802983e-09 0.340582053990938 0.08085808967374596 3097.8435506581854 5.5459754709399505 348.03147196987004 169.54798096260268 3.0000000033565115e-15 14.522878744794433 -2.092703568194586 ALVEFESNPEETREPGS(ph)PPSVQR ddPTM_PC-9_AZD4547_30min_R2 1 ALVEFESNPEETREPGSPPSVQR 23 1 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 ALVEFES(0.008)NPEET(0.074)REPGS(0.816)PPS(0.102)VQR 77.631 0.00014048 577530000.0 42991.0 31812.0 47107.0 64403.0 48793.0 43736.0 35746.0 61602.0 43970.0 43895.0 True False 56661.24373164932 42094.60688243395 46482.33040083301 49555.88336643114 42018.93417848692 41001.181006082894 38927.32475082225 52082.82637313488 46294.164433465856 42358.249410598175 1.337667267181077 0.9937758870625504 1.0973619317988854 1.1699228380772528 0.9919893943486163 0.9679621225287054 0.9190022083651668 1.2295792932392429 1.0929196809980277 1.0 15.370355346149848 -4.753746818921572 24.903726522287556 1.0551049302474236 1.3376677993004191 0.4678966255772514 0.09150917220729501 259.1200106975929 838797.594246468 0.023944920359560903 0.24968420119661777 1.763003526775402e-05 4.753746818921572 0.28256286905299555 ALVEFESNPEETREPGS(ph)PPSVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 ALVEFESNPEETREPGSPPSVQR 23 1 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 ALVEFES(0.011)NPEET(0.192)REPGS(0.543)PPS(0.254)VQR;ALVEFES(0.003)NPEET(0.114)REPGS(0.849)PPS(0.034)VQR;ALVEFES(0.043)NPEET(0.136)REPGS(0.794)PPS(0.027)VQR;ALVEFES(0.006)NPEET(0.104)REPGS(0.87)PPS(0.021)VQR;ALVEFES(0.013)NPEET(0.262)REPGS(0.643)PPS(0.082)VQR;ALVEFES(0.007)NPEET(0.083)REPGS(0.766)PPS(0.144)VQR 67.214 0.00070891 1450164700.0 113147.7 98257.0 131218.5 124164.8 157961.3 121167.7 128338.4 129578.9 115849.2 91358.4 True False 132301.37084105887 108011.30560210942 134347.2466889324 117208.24880371284 127009.91719967975 114813.45250845484 116181.25766244683 126177.59117519317 117543.27538484604 107920.9547273034 1.2259099372810438 1.0008371949176535 1.2448671069339912 1.0860564484429993 1.1768791104620107 1.0638661675905994 1.0765403063382428 1.169166743326363 1.0891608185069943 1.0 16.719615490754954 -6.7682148323805835 24.99692369071811 1.090119324401441 1.1408561198457603 0.1557879040651523 0.07563261678940394 391.57337841251206 1444638.4946132216 0.02487381780211364 0.022414557859421556 1.7052386502090767e-07 6.7682148323805835 0.050736795444319194 ALVEFESNPEETREPGS(ph)PPSVQR ddPTM_PC-9_Lapatinib_30min_R1 4 ALVEFESNPEETREPGSPPSVQR 23 1 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 ALVEFES(0.022)NPEET(0.221)REPGS(0.742)PPS(0.014)VQR;ALVEFESNPEET(0.004)REPGS(0.947)PPS(0.048)VQR;ALVEFES(0.001)NPEET(0.186)REPGS(0.795)PPS(0.017)VQR;ALVEFESNPEET(0.228)REPGS(0.766)PPS(0.005)VQR 88.945 1.135e-05 1049586600.0 88962.8 84138.2 98488.0 89450.9 98952.9 88085.7 83154.9 76048.9 92455.3 73262.1 True False 87694.17415822073 83943.38316733552 90390.69681467432 96029.41758545511 93132.68497088655 84318.47994879568 87460.25384194951 79582.40952415891 82042.01051652942 85925.35636938804 1.0205855158892638 0.9769337796688077 1.0519676686133257 1.1175911470489608 1.0838789491953298 0.981299159078439 1.0178631493358379 0.9261807327517947 0.9548055892120558 1.0 16.39079630963591 -7.195927038719349 1.8587652763238176 0.9613871501164042 1.0476631701729695 0.40144982563202025 0.04304887176640913 0.37686676974818606 2.5506213794879007 0.02392732454175846 0.015791951253285433 6.369025112603652e-08 7.195927038719349 0.08627602005656532 ALVEFESNPEETREPGSPPS(ph)VQR ddPTM_PC-9_Lapatinib_30min_R1 1 ALVEFESNPEETREPGSPPSVQR 23 1 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 ALVEFES(0.021)NPEET(0.296)REPGS(0.296)PPS(0.388)VQR 45.135 0.028011 357160000.0 21616.0 20606.0 19241.0 17877.0 17943.0 15866.0 18898.0 15543.0 19472.0 14958.0 True False 21307.7518761111 20558.288073028867 17659.07925240787 19191.73421592379 16887.62801729528 15187.448165452432 19876.44597137584 16265.18452251118 17278.85831074977 17543.47036971784 1.214568806915812 1.1718484222206667 1.0065898525350825 1.0939531239526616 0.9626161564045718 0.8657037544674063 1.132982560034701 0.9271360899373058 0.9849167779583209 1.0 14.09864654295065 -5.0709977160387565 1.011848512580562 0.9825964121668395 1.2888379908051812 0.5519211196775755 0.07150656496179558 0.947469524108073 1.0758660753330236 0.02415738519803286 0.2840411745039048 8.491849409010082e-06 5.0709977160387565 0.3062415786383418 ALVEFLTPLGS(ph)VFAFATREAFTK ddPTM_PC-9_AZD4547_30min_R2 1 ALVEFLTPLGSVFAFATREAFTK 23 1 A6NH11 A6NH11 GLTPD2 Glycolipid transfer protein domain-containing protein 2 1 ALVEFLT(0.464)PLGS(0.536)VFAFATREAFTK 55.453 0.032958 0.0 17769.0 9639.6 15548.0 26748.0 19329.0 12718.0 10867.0 13977.0 11538.0 14594.0 True False 23419.172381839842 12755.412187347863 15341.823361117273 20581.66185248049 16645.5019928263 11922.7414495007 11834.141947831518 11817.175809507908 12147.875124706152 14083.068502067885 1.662931084827223 0.9057267729312631 1.089380724013702 1.4614472584194549 1.181951361692387 0.8466011116646934 0.8403099044852231 0.8391051856186551 0.8625872353686571 1.0 13.781674090683774 -6.709742000839509 4.931612359533257 0.8644370783200636 1.2477180418457259 0.4905345360177431 0.19528838997452924 0.1805340465372557 9.28615397639758 0.0658403412654786 0.06436247944776696 1.9510032783621905e-07 6.709742000839509 0.3832809635256623 ALVHQLS(ph)NESR ddPTM_PC-9_AZD4547_30min_R2 3 ALVHQLSNESR 11 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 ALVHQLS(1)NESR;ALVHQLS(0.994)NES(0.006)R;ALVHQLS(0.888)NES(0.112)R 101.38 0.0021295000000000003 20304900.0 25122.1 29756.0 44687.0 59950.0 64001.0 53370.0 51707.0 78632.0 56922.0 60775.0 True False 33110.40522785858 39374.04508970531 44094.4211820329 46129.453718266974 55115.565887675286 50032.765463111464 56308.8228302682 66481.23118360336 59930.7807114338 58647.28574847029 0.564568416172989 0.6713702874260009 0.7518578331339575 0.786557350942199 0.939780335684382 0.8531130609811125 0.9601266642034991 1.133577288959829 1.0218849848988447 1.0 15.839776720065219 -5.640853548418034 0.457346452286272 1.0633071853296054 0.44370226322563433 0.8858621350955518 0.05616249948611732 0.7620691270308114 0.2170755273856643 0.04720610311134741 0.2373239851460747 2.286369676640174e-06 5.640853548418034 -0.6196049221039711 ALVHQLS(ph)NESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ALVHQLSNESR 11 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 ALVHQLS(0.983)NES(0.017)R;ALVHQLS(0.941)NES(0.059)R;ALVHQLS(0.999)NES(0.001)R;ALVHQLS(0.969)NES(0.031)R;ALVHQLS(0.994)NES(0.006)R 92.15100000000001 0.0044223 24981000.0 75061.3 85519.0 107201.0 105841.0 126559.0 105929.0 107835.0 112362.0 93023.0 87593.2 True False 87767.69556174752 94008.76114461834 109757.07840205664 99911.07191115183 101760.67246138336 100373.89676265318 97620.08814220829 109412.6165573797 94383.28539277396 103473.1537726103 0.8482170723685811 0.9085328678703402 1.0607300000080766 0.965574820795678 0.98344999404396 0.9700477186887726 0.9434339689378315 1.057401002754993 0.9121523984877085 1.0 16.65889698184182 -5.029802539222895 6.1076341892072845 0.9858532309168786 0.8611581941867414 0.5170823992943969 0.043607783364929785 0.11217938856731881 14.239649199418343 0.01041190939612416 0.03140621898352288 9.336787202337402e-06 5.029802539222895 -0.12469503673013715 ALVHQLS(ph)NESR ddPTM_PC-9_Lapatinib_30min_R1 3 ALVHQLSNESR 11 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 ALVHQLS(0.975)NES(0.025)R;ALVHQLS(1)NESR;ALVHQLS(0.996)NES(0.004)R 104.94 0.0014852 24553000.0 39231.2 41643.0 48800.0 34390.8 46617.7 44561.4 48045.3 46403.3 56624.0 49718.5 True False 38671.75589387904 41546.5781920383 44787.8523734475 36920.014156345685 43875.738539924554 42655.612799697 50532.850546541624 48559.3667215752 50246.408842845885 58312.27647926301 0.6631837792789906 0.7124842434648059 0.768069008408117 0.6331430769895455 0.7524271249387361 0.7315031306463601 0.8665902550471014 0.832746887164384 0.8616780526603947 1.0 15.831512025432357 -7.982586391417827 0.454386260738194 1.001855706756504 0.6808632995897199 0.8321474842717279 0.04264201207900617 0.3761150674335298 0.2036589856220187 0.04838321415495825 0.03273167549281216 1.0409110252683356e-08 7.982586391417827 -0.320992407166784 ALVILAK ddPTM_PC-9_Lapatinib_30min_R1 2 ALVILAK 7 0 Q99497;K7ELW0 Q99497 PARK7 Protein deglycase DJ-1 0 ; 126.05 0.021051 9727600.0 115580.0 106935.0 120300.0 100246.0 106192.0 105738.0 112945.0 100136.0 97685.0 100057.0 False True 113931.80800522404 106687.3985775666 110409.39837142931 107618.42525085263 99945.99534150476 101215.83222731698 118792.73945587076 104788.68412444057 86682.68663134701 117351.7191324281 0.9708575966974562 0.9091251441930124 0.940841763441364 0.917058787433768 0.8516790046230045 0.8624997824965629 1.0122794990486377 0.8929454540515891 0.7386571519546982 1.0 16.840479451071324 -1.52288162378248 0.5718399494025648 0.8932582052947119 4.668833143403476 0.07663299682015623 0.07354129069634338 428.125733612046 3.652781156347444 0.03520200553414028 2001.390112714765 0.02999980116077525 1.52288162378248 3.775574938108764 ALVVPEPEPDS(ph)DSNQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 ALVVPEPEPDSDSNQER 17 0 Q5VTR2;C9J0A5;C9JXC9 Q5VTR2 RNF20 E3 ubiquitin-protein ligase BRE1A 1 ALVVPEPEPDS(0.515)DS(0.485)NQER;ALVVPEPEPDS(0.688)DS(0.312)NQER;ALVVPEPEPDS(0.852)DS(0.148)NQER;ALVVPEPEPDS(0.701)DS(0.299)NQER;ALVVPEPEPDS(0.904)DS(0.096)NQER;ALVVPEPEPDS(0.739)DS(0.261)NQER 202.84 8.2496e-14 27921500.0 133122.8 156137.3 155351.3 151816.7 170120.7 129571.8 146547.9 144342.1 116310.1 98865.5 True False 155657.86074485013 171637.57926853263 159055.46416508636 143310.90249538227 136786.77005666288 122776.82670988236 132665.8219970838 140553.272818097 118010.91517540875 116789.0325311328 1.332812314404231 1.469637820852559 1.361904116490446 1.2270921283398717 1.1712295845947625 1.0512701753664528 1.135944181759693 1.203480068050305 1.010462306415204 1.0 16.833545273861375 -5.982943538555344 1.563903062956946 1.0980919519878067 1.4095070431582757 0.7968087798500706 0.06688207220647219 0.16711581008817866 0.8270353008226317 0.022366063327947053 0.039078445814991446 1.040055371810752e-06 5.982943538555344 0.31141509117046895 ALVVPEPEPDS(ph)DSNQER ddPTM_PC-9_Lapatinib_30min_R1 3 ALVVPEPEPDSDSNQER 17 0 Q5VTR2;C9J0A5;C9JXC9 Q5VTR2 RNF20 E3 ubiquitin-protein ligase BRE1A 1 ALVVPEPEPDS(0.756)DS(0.244)NQER;ALVVPEPEPDS(0.875)DS(0.125)NQER;ALVVPEPEPDS(0.91)DS(0.09)NQER 273.52 1.6052999999999997e-82 24747400.0 138866.0 136817.0 164453.0 127826.0 126861.0 136305.0 125173.0 125397.0 132335.0 100584.0 True False 136885.74537509432 136500.20864251122 150932.30914693754 137226.7504550357 119399.28539832224 130475.5528924742 131653.8454638071 131223.4024042547 117430.03875067132 117969.8103802448 1.1603455573411448 1.157077460771858 1.279414696526567 1.1632361704466694 1.0121172952085784 1.1060079902809066 1.1159960759405767 1.1123473198887954 0.9954244935392057 1.0 16.84805818158977 -6.08460645436006 5.91249395976389 1.0686652751873658 1.198936086914774 0.5979729415824081 0.05348366000787031 0.17005881414148494 9.415173966855962 0.015998496869930053 0.02093378062712705 8.229880811735799e-07 6.08460645436006 0.1302708117274083 ALVVPEPEPDS(ph)DSNQERK ddPTM_PC-9_Lapatinib_30min_R1 1 ALVVPEPEPDSDSNQERK 18 1 Q5VTR2;C9J0A5;C9JXC9 Q5VTR2 RNF20 E3 ubiquitin-protein ligase BRE1A 1 ALVVPEPEPDS(0.587)DS(0.413)NQERK 135.81 3.5161e-05 6920300.0 58056.0 77409.0 82289.0 69202.0 74665.0 70761.0 78841.0 72799.0 74117.0 62710.0 True False 57228.11079383349 77229.7642164948 75523.51606472605 74291.34593110473 70273.35149703798 67734.71698194763 82923.0012080243 76181.50730581567 65769.16297338954 73549.33994417738 0.7780914259362299 1.050040208044162 1.0268415205635704 1.0100885471914571 0.9554586288656591 0.9209425541188684 1.1274472520210428 1.0357877767990311 0.8942182625065996 1.0 16.166424773870684 -4.754322825308797 24.994023716460127 1.0043450193520598 0.7780910322121632 0.528946960824364 0.06345280509496495 202.92450342292875 712629.0123352231 0.016091664167597476 0.15818679224833218 1.760666798586432e-05 4.754322825308797 -0.22625398713989653 ALVVPEPEPDSDS(ph)NQER ddPTM_PC-9_AZD4547_30min_R2 7 ALVVPEPEPDSDSNQER 17 0 Q5VTR2;C9J0A5;C9JXC9 Q5VTR2 RNF20 E3 ubiquitin-protein ligase BRE1A 1 ALVVPEPEPDS(0.143)DS(0.857)NQER;ALVVPEPEPDS(0.494)DS(0.506)NQER;ALVVPEPEPDS(0.466)DS(0.534)NQER;ALVVPEPEPDS(0.064)DS(0.936)NQER;ALVVPEPEPDS(0.274)DS(0.726)NQER;ALVVPEPEPDS(0.227)DS(0.773)NQER;ALVVPEPEPDS(0.044)DS(0.956)NQER 237.34 1.9449e-37 34544200.0 224500.8 220566.80000000002 314819.2 369835.5 305843.5 278936.0 252748.4 323591.2 257734.6 252881.8 True False 295887.3844932719 291860.70468113985 310644.4917087891 284575.6393765157 263382.4092680928 261494.08782496722 275242.51796147064 273587.61542603077 271357.92478038557 244028.48515322935 1.2125116635768136 1.1960108038120054 1.2729845514294387 1.1661574639445316 1.079310102272326 1.0715719833312531 1.1279114312767278 1.121129835536375 1.111992825796528 1.0 17.896690036121292 -1.5228787474413805 0.11252580818872701 0.9562877599228327 1.8333308563511101 0.6780634528085916 0.042404213188597675 69.65010822497048 0.5471287898899206 0.4117065435713276 9.502073567878975 0.02999999985072044 1.5228787474413805 0.8770430964282775 ALVVPEPEPDSDS(ph)NQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ALVVPEPEPDSDSNQER 17 0 Q5VTR2;C9J0A5;C9JXC9 Q5VTR2 RNF20 E3 ubiquitin-protein ligase BRE1A 1 ALVVPEPEPDS(0.082)DS(0.918)NQER;ALVVPEPEPDS(0.446)DS(0.554)NQER 184.92 5.06e-34 0.0 15834.4 19100.0 18374.5 18786.4 17230.1 13253.5 14726.0 13717.0 14851.2 8588.6 True False 18514.85117634438 20996.121772497496 18812.617765679297 17733.858914330573 13853.985592307763 12558.463128546693 13331.04667299262 13356.943284362858 15068.370704289948 10145.64519267981 1.8249062356037284 2.0694713223015544 1.854255437520405 1.7479281580954298 1.3655105544498598 1.2378180874694649 1.3139673643043528 1.316519849718383 1.4852057624843746 1.0 13.308572992961638 -6.151214877467901 2.0496578764246873 1.2887729455461239 1.9369674770688416 0.8412092553227682 0.127109904630448 0.11956391143970069 0.9884937378446897 0.04071102310599808 0.05727912133780171 7.059681733848196e-07 6.151214877467901 0.6481945315227178 ALVVPEPEPDSDS(ph)NQER ddPTM_PC-9_Lapatinib_30min_R1 3 ALVVPEPEPDSDSNQER 17 0 Q5VTR2;C9J0A5;C9JXC9 Q5VTR2 RNF20 E3 ubiquitin-protein ligase BRE1A 1 ALVVPEPEPDS(0.103)DS(0.897)NQER;ALVVPEPEPDS(0.108)DS(0.892)NQER;ALVVPEPEPDS(0.059)DS(0.941)NQER 254.59 1.3784e-57 10706900.0 68195.90000000001 74977.4 84432.4 64841.2 71172.1 71503.8 71281.0 63154.3 74194.3 55081.5 True False 67223.41396040349 74803.79443689772 77490.69399048925 69609.83815190227 66985.89700773239 68445.7491574989 74971.58139938841 66088.67933410718 65837.75663338436 64602.26388351471 1.040573656700561 1.1579128956189142 1.1995043104095215 1.077513913094699 1.036897052532333 1.0594945911015508 1.1605101260007045 1.0230087207667002 1.0191246045509703 1.0 15.979297102305981 -7.814611450337877 0.4513943391071986 0.992241529562607 1.1251974987371742 0.313373198831152 0.05494102769570402 1.2435032491478697 0.6431928920939716 0.06454281816720737 0.04787588027990076 1.5324578905980393e-08 7.814611450337877 0.1329559691745672 ALVVPEPEPDSDS(ph)NQERK ddPTM_PC-9_Lapatinib_30min_R1 1 ALVVPEPEPDSDSNQERK 18 1 Q5VTR2;C9J0A5;C9JXC9 Q5VTR2 RNF20 E3 ubiquitin-protein ligase BRE1A 1 ALVVPEPEPDS(0.125)DS(0.875)NQERK 96.012 0.00039459 13410000.0 33827.0 49768.0 42990.0 40438.0 42688.0 39073.0 44967.0 50809.0 41660.0 37770.0 True False 33344.62077688793 49652.76525373682 39455.52814619896 43411.94541721352 40177.17576783709 37401.938873611674 47295.17123477919 53169.77162737375 36967.81210075162 44298.49417463849 0.7527258295831238 1.1208680154677522 0.8906742516044215 0.9799869324241607 0.9069648193784224 0.8443162588362837 1.0676473798031796 1.2002613772324162 0.834516224299024 1.0 15.434970038065527 -7.2804350753537195 24.633096333209664 1.042294703442681 0.9265955568824196 0.153055207005931 0.1224032978734046 1236.5029627815188 1603455.9803381038 0.04895897218186271 0.03306934729626257 5.242819724334932e-08 7.2804350753537195 -0.11569914656026148 ALWFQGR ddPTM_PC-9_Lapatinib_30min_R1 1 ALWFQGR 7 0 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2;H0Y8T4 A0A0R4J2E8 MATR3 Matrin-3 0 114.6 0.039596 2118500.0 8899.0 7508.6 9226.9 8008.8 9567.5 9685.2 9178.0 7044.8 9277.5 8378.1 False True 8772.098628123273 7491.214298027012 8468.299898864 8597.79386857361 9004.758460428726 9270.986573303913 9653.191931701109 7372.127126306808 8232.570253593925 9826.243421883479 0.8927214858719479 0.7623680766287294 0.8618044083871076 0.8749827883793254 0.9163988793901371 0.9434924594537335 0.9823888455890502 0.750248778682681 0.8378146052498178 1.0 13.262424263542819 -5.6869756191172 2.790293651799097 0.8973548800821028 0.8255326235080054 0.13597341322785894 0.07387316976142783 0.5584602738176323 8.77050986652815 0.02214972439655323 0.041850550249980016 2.0560060149838185e-06 5.6869756191172 -0.07182225657409746 ALYDYAGQEADELS(ph)FR ddPTM_PC-9_AZD4547_30min_R2 2 ALYDYAGQEADELSFR 16 0 A0A0C4DGG1;Q9UKS6 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 1 ALYDYAGQEADELS(1)FR;ALYDYAGQEADELS(1)FR 163.7 1.585e-15 2971600.0 17538.0 21268.7 25315.5 32686.0 27179.4 24200.9 22333.2 25146.3 23316.9 23079.9 True False 23114.719186938346 28143.39134290276 24979.799929146146 25150.747693665955 23406.009460594098 22687.61389724968 24320.811534858825 21260.517139488344 24549.383731605205 22271.87972597481 1.0378432117689897 1.263628920826123 1.121584717432413 1.1292602152629998 1.0509220482767154 1.0186663261650977 1.0919963574737892 0.9545901558858118 1.1022591731659825 1.0 14.442935704936003 -6.211447393350063 2.1827836218022854 1.0333115254424918 1.152705009867689 0.37048834157344324 0.06491565173895286 0.3094123191972318 2.8939160504181354 0.02035486300088353 0.027149433658770313 6.145434676391383e-07 6.211447393350063 0.11939348442519715 ALYDYAGQEADELS(ph)FR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALYDYAGQEADELSFR 16 0 A0A0C4DGG1;Q9UKS6 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 1 ALYDYAGQEADELS(1)FR 120.99 0.00093219 0.0 3288.5 3239.0 6218.1 4364.0 5861.0 4356.6 5904.2 3557.7 3712.1 4218.7 True False 3845.1780991643823 3560.5465141947316 6366.363086275568 4119.499228278892 4712.57912354054 4128.132226644021 5344.911433293699 3464.314144694739 3766.3824398967554 4983.516914789177 0.7715792210423448 0.7144646190782233 1.277483992756728 0.826624911426264 0.9456332152812412 0.8283572218633993 1.072517967668985 0.6951544870679532 0.7557679655344541 1.0 12.282948509842498 -7.777552829343583 24.999753444507817 0.7940959909749024 0.9193287807305464 0.0667604279884505 0.1693393337136226 613.0372756732804 951103.667844565 0.09084254773473172 0.04385367574461122 1.6689647752128927e-08 7.777552829343583 0.125232789755644 ALYDYAGQEADELS(ph)FR ddPTM_PC-9_Lapatinib_30min_R1 1 ALYDYAGQEADELSFR 16 0 A0A0C4DGG1;Q9UKS6 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 1 ALYDYAGQEADELS(1)FR 92.264 0.017816 0.0 5751.7 6209.2 3942.7 4576.6 6664.7 5092.4 3687.5 5249.2 6720.3 3690.4 True False 5669.679703267404 6194.822978892111 3618.5464252621205 4913.178431090046 6272.695449304345 4874.609922964197 3878.420706923927 5493.096995146731 5963.389046103719 4328.2807228510965 1.309914967699394 1.4312433447735105 0.8360239681677891 1.1351339586526794 1.4492348927803456 1.1262231438059835 0.8960649632654046 1.2691175427106667 1.3777731685978896 1.0 12.079578356916286 ALYEAGER ddPTM_PC-9_AZD4547_30min_R2 3 ALYEAGER 8 0 P04083 P04083 ANXA1 Annexin A1 0 ;; 143.89 0.0077832 43501600.0 148434.0 143560.0 210965.0 285589.0 264669.0 203586.0 171085.0 253044.0 186648.0 193801.0 False True 195632.9243810014 189962.96253119025 208167.4662579177 219750.8683560656 227924.27786948893 190855.73523651864 186311.23356443868 213941.86417264922 196513.8322305558 187016.08597843378 1.0460753862828744 1.0157573426763744 1.113099256509534 1.1750372552519717 1.2187415680155587 1.0205311176201584 0.9962310599630644 1.1439757337094545 1.0507857182575047 1.0 17.512802841679225 ALYEAGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ALYEAGER 8 0 P04083 P04083 ANXA1 Annexin A1 0 ;;; 120.46 0.015734 46111600.0 178924.0 183231.0 190172.0 220211.0 238129.0 183697.0 222858.0 189403.0 169299.0 160387.0 False True 209212.2992899156 201420.96274850733 194706.4217113265 207873.29160369493 191469.33187332956 174063.60593991316 201747.27688780354 184431.37193906697 171774.67759275934 189463.89347720676 1.104233083413778 1.0631100155911186 1.0276703288310205 1.0971657332097575 1.0105848051537274 0.9187165044766363 1.0648323181011505 0.97343809711825 0.9066354250416822 1.0 17.531563411674455 -6.472801954210583 5.663773808967899 0.9754630417425174 1.0680682284573364 0.5215771682397505 0.04516129742904893 0.1831758105151878 13.705759347875201 0.01436147565212626 0.016000375655881607 3.366650594612736e-07 6.472801954210583 0.09260518671481899 ALYEAGER ddPTM_PC-9_Lapatinib_30min_R1 4 ALYEAGER 8 0 P04083 P04083 ANXA1 Annexin A1 0 ;;; 143.89 0.0077832 130367000.0 491930.0 493627.0 518744.0 469235.0 436818.0 456738.0 456384.0 399747.0 420373.0 406520.0 False True 484914.98799108533 492484.0370098514 476094.87072974705 503744.10722207354 411125.2240572303 437204.38044828037 480013.3304159372 418320.70496816986 373026.16601606447 476786.4403461494 1.0170486132932695 1.0329237481089133 0.9985495191182445 1.0565403388073553 0.862283801021588 0.9169815738276192 1.0067679988286686 0.8773754233959903 0.7823757859918281 1.0 18.862983681034834 -6.257630768193333 24.990572516387925 0.9069239366013438 1.0247614258137159 0.4644550439472491 0.0623973750354424 314.0864434984822 2060908.6648922327 0.019120375717780965 0.023746882358743285 5.525470082862269e-07 6.257630768193333 0.11783748921237203 ALYEAGERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ALYEAGERR 9 1 P04083 P04083 ANXA1 Annexin A1 0 113.71 0.0013183 3313100.0 6070.1 5285.4 6925.8 10873.0 10206.0 11488.0 8194.5 7992.2 9847.4 10545.0 False True 7097.648040060123 5810.099582008286 7090.937338242769 10263.82106074162 8206.207564384023 10885.549056531812 7418.25763695763 7782.413218435876 9991.399595549508 12456.725025825932 0.569784435744139 0.46642272105729915 0.5692457145470795 0.8239582265372425 0.6587772907702856 0.8738692580885685 0.5955223079563619 0.624755961322175 0.802088797403396 1.0 13.604637201519852 -14.5228643665176 0.049968551618700355 2.3318840373753273 3.2394792614060396e-10 0.5374084285081447 0.10815773118885738 487.6466597878864 1.7952510456737454 86.94115343017332 19.378157344785688 3.0000993266184622e-15 14.5228643665176 -2.3318840370513794 ALYEAGERR ddPTM_PC-9_Lapatinib_30min_R1 3 ALYEAGERR 9 1 P04083 P04083 ANXA1 Annexin A1 0 ;; 90.709 0.005292600000000001 13071700.0 73620.0 42246.0 65098.0 48927.0 60683.0 60625.0 42081.0 44907.0 68426.0 40065.0 False True 72570.16529974536 42148.18198258652 59745.89372554684 52525.25479568736 57113.74524736834 58032.21007377752 44259.748276085644 46993.543161063484 60719.14332227622 46990.18186674323 1.5443686833462986 0.896957200593778 1.2714548306064617 1.1177921154815005 1.2154399701906653 1.2349858580745174 0.9418935300484542 1.0000715318431792 1.2921665954489423 1.0 15.520071730981622 -7.238521554813316 24.51843888807489 1.0585388512999858 1.1974836472133272 0.15787247784377967 0.17298265565353085 1258.9205240871156 1346846.7757951093 0.06267869785552635 0.04851447012103758 5.77402214496304e-08 7.238521554813316 0.1389447959133414 ALYESELADAR ddPTM_PC-9_Lapatinib_30min_R1 2 ALYESELADAR 11 0 Q03252 Q03252 LMNB2 Lamin-B2 0 ; 128.86 0.0013304999999999999 4298700.0 19728.0 14019.7 21884.0 19762.8 16631.4 17784.9 18347.0 14501.4 22061.1 18950.7 False True 19446.67510232789 13987.238246017803 20084.781994682904 21216.22223876818 15653.173750590473 17024.281285626806 19296.917887439533 15175.187983963437 19576.34660431807 22226.3032447795 0.8749397004153405 0.6293101507693645 0.9036492381791112 0.9545547005776335 0.7042634835942445 0.7659519938218002 0.8682018631223336 0.6827580734788982 0.8807738465872029 1.0 14.439980393864644 -8.529648320426565 23.514357887075224 1.000000006415062 0.7981359633492032 0.28747232728845995 0.0990302881320579 467.83721987004634 1625052.918415142 0.09427611786228411 0.024341988936386998 2.9536000015480026e-09 8.529648320426565 -0.2018640430658588 ALYETELADARR ddPTM_PC-9_AZD4547_30min_R2 1 ALYETELADARR 12 1 P20700;E9PBF6;A0A0D9SFE5;A0A0D9SFY5 P20700 LMNB1 Lamin-B1 0 110.38 0.0021257 0.0 11494.0 9644.1 14414.0 18650.0 17065.0 14290.0 12348.0 15913.0 11945.0 13385.0 False True 15148.852909948073 12761.366724345571 14222.860942059711 14350.53063962767 14695.819313341653 13396.444040994244 13446.948078754365 13454.011494362125 12576.388313799183 12916.395224076925 1.1728390659423082 0.9879975413385949 1.1011478586182821 1.1110321719544034 1.137764760089392 1.0371658507338393 1.0410759229237936 1.0416227794952457 0.9736763311760585 1.0 13.656915870789906 -7.507821350531356 1.1391764556860642 0.9944193300375517 1.094008209016822 0.4285647080153917 0.048124493960713374 0.5293545670613848 1.2821543726556714 0.03706239294896758 0.01729418363372725 3.105836928813545e-08 7.507821350531356 0.09958887897927027 ALYETELADARR ddPTM_PC-9_Lapatinib_30min_R1 1 ALYETELADARR 12 1 P20700;E9PBF6;A0A0D9SFE5;A0A0D9SFY5 P20700 LMNB1 Lamin-B1 0 123.11 0.0017769 0.0 14594.0 8717.9 12270.0 9098.0 8813.8 9421.6 6981.7 6065.4 12092.0 5384.1 False True 14385.886883788178 8697.714238176179 11261.207963569694 9767.097270038299 8295.389612597512 9018.660130822298 7343.178264279538 6347.220626831328 10730.071625595016 6314.734511137711 2.2781459550539847 1.377368157415874 1.7833224728145838 1.5467154245061974 1.3136561161781846 1.4281930799965536 1.1628641317109838 1.0051444942992172 1.699211836486504 1.0 12.624506365069765 -1.5228787452803376 0.3640797847381657 1.2042203431629528 12.486529028701694 0.5544384108838543 0.2474881858344383 50.020326665114126 0.695417094996092 0.1927503415105537 392.5612983255653 0.029999999999999995 1.5228787452803376 11.282308685538741 AMADELS(ph)EK ddPTM_PC-9_AZD4547_30min_R2 5 AMADELSEK 9 0 Q03135;E9PCT5 Q03135 CAV1 Caveolin-1;Caveolin 1 AMADELS(1)EK;AMADELS(1)EK;AMADELS(1)EK;AMADELS(1)EK;AMADELS(1)EK 106.29 0.0025792 256823000.0 2090005.0 3617260.0 2371776.0 1761652.0 2026525.0 1915421.0 3180151.0 2608290.0 2553886.0 1939487.0 True False 2754583.115195403 4786468.555625328 2340324.7005490903 1355530.3486520827 1745176.984117766 1795649.4220745456 3463178.2782311873 2205238.7130415277 2688879.200098393 1871586.150463894 1.4717907131940724 2.557439610481701 1.2504498924449798 0.7242682087148908 0.9324588043597158 0.959426538623121 1.850397470280916 1.1782726178514058 1.4366847069433184 1.0 20.835830027386486 -5.386954590827566 7.47986028351604 1.160153604194954 2.0097142540804294 0.4435410788222697 0.38102930377698324 0.22344646207012717 12.484317065801257 0.10097417364468911 0.21140846063772578 4.1024699554790535e-06 5.386954590827566 0.8495606498854753 AMADELS(ph)EK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 AMADELSEK 9 0 Q03135;E9PCT5 Q03135 CAV1 Caveolin-1;Caveolin 1 AMADELS(1)EK;AMADELS(1)EK;AMADELS(1)EK;AMADELS(1)EK;AMADELS(1)EK;AMADELS(1)EK 84.31 0.011717 254413000.0 2378820.0 2694450.0 1813868.0 1700821.0 3119000.0 1269110.0 1811246.0 1428655.0 1422854.0 1469576.0 True False 2781507.242163364 2961937.1890003155 1857117.4922526928 1605529.5135060772 2507854.3399288375 1202555.637459532 1639671.666594537 1391154.3200350977 1443660.5479746964 1735998.4956427852 1.602252103987832 1.7061864952271195 1.0697690677232188 0.9248449912461477 1.444617807114089 0.6927169813095164 0.9445121471648618 0.8013568695634136 0.8316024187798358 1.0 20.727334266916685 -4.954646309490764 0.6456585857162619 0.8730617616917287 2.148094422906433 0.6312605802403504 0.2042457690855243 1.7574668680417835 0.6449509790689635 0.09873857362654521 1.6034724490704562 1.1100784979291054e-05 4.954646309490764 1.2750326612147043 AMADELS(ph)EK ddPTM_PC-9_Lapatinib_30min_R1 11 AMADELSEK 9 0 Q03135;E9PCT5 Q03135 CAV1 Caveolin-1;Caveolin 1 AMADELS(1)EK;AMADELS(1)EK;AMADELS(1)EK;AMADELS(1)EK;AMADELS(1)EK;AMADELS(1)EK;AMADELS(1)EK;AMADELS(1)EK;AMADELS(1)EK;AMADELS(1)EK;AMADELS(1)EK 122.69 0.0015411 427709200.0 4682391.0 6128785.0 2035755.0 1697088.0 2451095.0 1747731.0 1877719.0 1542027.0 2597231.0 1013450.0 True False 4615619.245694653 6114594.17488392 1868383.082141547 1821897.5128396081 2306926.4111381783 1672984.6192899502 1974938.102070372 1613675.2038663249 2304703.494725091 1188623.4821627585 3.883163436495726 5.144264997825987 1.5718880790929124 1.5327793369222158 1.9408386640154651 1.4074975334038269 1.661533809240312 1.357599970118514 1.9389685037448279 1.0 20.18086035720694 -5.268962297690945 24.997791518308954 1.57619872205723 4.513714263143038 0.9047764638479038 0.3843422773886179 121.98162098847108 405331.8032506551 0.09115114344263983 0.19585864541699882 5.383165132380829e-06 5.268962297690945 2.9375155410858085 AMGDEES(ph)GES(ph)DS(ph)S(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AMGDEESGESDSSPK 15 0 A0A0J9YVY4;A0A1B0GXK6;A0A0G2JPE0;A0A0G2JLW6;H0YBY6;A0A1B0GTN4;Q9P1A6-3;Q9P1A6-2;Q9P1A6 A0A0J9YVY4 DLGAP2 Disks large-associated protein 2 4 AMGDEES(1)GES(1)DS(1)S(1)PK 45.873000000000005 0.045833 0.0 5763.3 5928.5 4223.2 6572.8 6718.8 4838.3 6619.5 5408.2 3733.1 3437.9 True False 6738.912859636333 6517.042299908455 4323.89710457519 6204.547325305115 5402.299371309361 4584.571030659633 5992.453038970166 5266.240480461561 3787.6895251686574 4061.164055598573 1.6593549946218777 1.6047227372960462 1.0646940250085248 1.527775593490677 1.3302342129867784 1.1288810222624495 1.4755505950834928 1.2967317764968673 0.9326610482398726 1.0 11.98767759250002 -1.522878745281317 0.13448419672814377 0.916746776016768 3.2199257329846978 0.478470940811931 0.1791159222777097 77.49558974107174 0.7029618923120753 0.8904124434986023 34.03132788117186 0.029999999999932338 1.522878745281317 2.3031789569679297 AMGT(ph)LGVSLS(ph)S(ph)CSVPGS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 AMGTLGVSLSSCSVPGSK 18 0 H0YCY6;Q3LXA3-2;Q3LXA3 H0YCY6 TKFC;DAK Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing);ATP-dependent dihydroxyacetone kinase;FAD-AMP lyase (cyclizing) 4 AMGT(0.996)LGVS(0.029)LS(0.985)S(0.975)CS(0.259)VPGS(0.755)K 55.18899999999999 0.014915000000000001 10044000.0 0.0 0.0 0.0 0.0 0.0 608.49 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 570.4410241080889 0.0 0.0 0.0 0.0 0.0 AMKPPGGES(ph)SNLFGSPEEATPSSRPNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AMKPPGGESSNLFGSPEEATPSSRPNR 27 2 A6NGP5;Q9H910;Q9H910-3;H3BMV3;H3BMM8;B4E1P3 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 AMKPPGGES(0.445)S(0.445)NLFGS(0.11)PEEATPSSRPNR 73.153 8.4957e-05 11026000.0 17897.0 14600.0 15909.0 19774.0 18635.0 18226.0 19689.0 17791.0 18079.0 13927.0 True False 20926.608618137438 16049.39151196143 16288.330895218474 18666.126888172974 14983.605522466794 17270.196474960736 17823.91538398423 17324.00510112267 18343.371172892294 16451.854853928668 1.2719908365311288 0.9755369017329295 0.990060454571106 1.1345910265987755 0.9107547845213783 1.0497416022872734 1.0833985311831216 1.0530122745998902 1.1149728304654922 1.0 14.005962628416196 -4.752297249222605 24.99488776544153 1.0361801211233497 1.271991293913749 0.5501176118858908 0.06437000008589178 277.93052192241794 759816.389341601 0.01581352076560096 0.19184421502077323 1.7688978365770547e-05 4.752297249222605 0.23581117279039931 AMKPPGGES(ph)SNLFGSPEEATPSSRPNR ddPTM_PC-9_Lapatinib_30min_R1 1 AMKPPGGESSNLFGSPEEATPSSRPNR 27 2 A6NGP5;Q9H910;Q9H910-3;H3BMV3;H3BMM8;B4E1P3 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 AMKPPGGES(0.74)S(0.202)NLFGS(0.058)PEEATPSSRPNR 65.189 0.00036185 9242200.0 17896.0 13857.0 18591.0 14541.0 15534.0 17112.0 15467.0 16000.0 17550.0 15038.0 True False 17640.799758275527 13824.914967871544 17062.519743335317 15610.393647354009 14620.320661019057 16380.159650020309 16267.80557938778 16743.4184108717 15573.334190307029 17637.298263124547 1.000198527864004 0.783845391829439 0.9674111923938511 0.8850785088775008 0.8289433247033486 0.9287227219073219 0.9223524678606783 0.9493187766676409 0.8829773108088339 1.0 14.10634196080123 -6.962185593813398 24.99974267825472 0.9331672469401676 0.8895215787875824 0.1027516141265652 0.06366834309416494 387.1912203334943 255977.59242040123 0.02109521517300652 0.018604178143510643 1.0909740139275007e-07 6.962185593813398 -0.04364566815258519 AMKPPGGESSNLFGS(ph)PEEATPSSRPNR ddPTM_PC-9_AZD4547_30min_R2 3 AMKPPGGESSNLFGSPEEATPSSRPNR 27 2 A6NGP5;Q9H910;Q9H910-3;H3BMV3;H3BMM8;B4E1P3 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 AMKPPGGES(0.02)S(0.02)NLFGS(0.958)PEEAT(0.001)PSSRPNR;AMKPPGGES(0.096)S(0.096)NLFGS(0.777)PEEAT(0.011)PS(0.011)S(0.011)RPNR;AMKPPGGES(0.168)S(0.168)NLFGS(0.663)PEEAT(0.001)PSSRPNR 77.51 3.601e-05 22683500.0 99316.0 85174.0 100576.0 127150.0 110040.0 103652.0 80087.0 116627.0 89226.0 94321.0 True False 130896.4220988693 112704.82983164942 99242.29652480895 97837.5319479173 94762.84542866192 97170.62405438331 87214.58785092332 98604.97697184495 93942.30420151065 91018.85049907803 1.4381243157997825 1.2382581104206656 1.0903488231354252 1.0749150468441517 1.0411342805260084 1.0675879064784233 0.9582035740146679 1.0833467620297377 1.0321192114205202 1.0 16.473877745796756 -4.380191103900862 0.9063909557146721 1.0306893903663426 1.9950343477039267 0.9375979125087324 0.032914953243036206 0.8625992554988259 0.3385978290950645 0.010862095887625808 0.976948868682924 4.166859875407851e-05 4.380191103900862 0.9643449573375842 AMKPPGGESSNLFGS(ph)PEEATPSSRPNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AMKPPGGESSNLFGSPEEATPSSRPNR 27 2 A6NGP5;Q9H910;Q9H910-3;H3BMV3;H3BMM8;B4E1P3 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 AMKPPGGES(0.003)S(0.004)NLFGS(0.948)PEEAT(0.021)PS(0.012)S(0.012)RPNR;AMKPPGGES(0.005)S(0.005)NLFGS(0.583)PEEAT(0.357)PS(0.034)S(0.015)RPNR;AMKPPGGES(0.075)S(0.075)NLFGS(0.85)PEEATPSSRPNR 74.859 5.0498e-05 27838700.0 136812.0 131234.0 129923.0 131210.0 134101.0 133258.0 134754.0 116611.0 119445.0 106497.0 True False 159971.56943982904 144262.0442247084 133020.85705572128 123858.7290885593 107824.87170208302 126269.7158926982 121989.12558552544 113550.08480956756 121191.65715726085 125804.06307021157 1.2715930275681835 1.1467200717054375 1.0573653490148565 0.9845367952816708 0.8570857655201938 1.0037014132224549 0.9696755622069455 0.902594733734434 0.9633365902468783 1.0 16.940818991857398 -5.133623061597672 1.2224351875415573 0.9465000373297523 1.314480056178226 0.8529114078364803 0.0434847104797934 0.30136531360880325 0.584605999989018 0.013771071692654846 0.1201563214904836 7.351516535331792e-06 5.133623061597672 0.36798001884847364 AMKPPGGESSNLFGS(ph)PEEATPSSRPNR ddPTM_PC-9_Lapatinib_30min_R1 1 AMKPPGGESSNLFGSPEEATPSSRPNR 27 2 A6NGP5;Q9H910;Q9H910-3;H3BMV3;H3BMM8;B4E1P3 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 AMKPPGGES(0.003)S(0.003)NLFGS(0.937)PEEAT(0.019)PS(0.019)S(0.019)RPNR 40.396 0.027367000000000002 19844000.0 30356.0 25553.0 31933.0 32384.0 26072.0 25297.0 22575.0 18283.0 26149.0 21879.0 True False 29923.11787339137 25493.83359847163 29307.592004944676 34765.62738985714 24538.496219524197 24215.106280187207 23743.823039676663 19132.49492537295 23203.824258822708 25660.75599806504 1.166104298550196 0.9934950318842516 1.1421172473310852 1.3548169583343006 0.9562655216149724 0.9436630114098414 0.9252970973055928 0.7455935798156392 0.9042533376870269 1.0 14.647276054209035 -6.4701182731351885 9.474731591352944 0.8958259581734151 1.151325747081428 0.5974409958820049 0.10162514274603661 0.37805560471683275 66.05159413606835 0.03318227836071093 0.03749616365311508 3.3875188993320125e-07 6.4701182731351885 0.25549978890801284 AMLDSGIYPPGS(ph)PGK ddPTM_PC-9_AZD4547_30min_R2 3 AMLDSGIYPPGSPGK 15 0 O95295 O95295 SNAPIN SNARE-associated protein Snapin 1 AMLDSGIYPPGS(1)PGK;AMLDS(0.011)GIY(0.011)PPGS(0.977)PGK;AMLDSGIYPPGS(1)PGK 109.48 0.00055171 50959000.0 261045.0 216642.0 242545.0 300782.0 306999.0 269016.0 277295.0 279215.0 251248.0 277706.0 True False 344051.8799266911 286667.28983478755 239328.69482391205 231441.3569355757 264377.48803847516 252194.3869931496 301973.71780840564 236068.73747240074 264528.4563470417 267983.59746712726 1.2838542477171384 1.0697195371069386 0.8930721771255787 0.8636400105195465 0.9865435442216032 0.9410814295232585 1.1268365700831666 0.8809074126313219 0.9871068932847303 1.0 18.031785174459344 -4.854284420100966 2.9913661560219547 0.9589322322094458 1.3112392261473567 0.6517175780822597 0.07214469774963493 0.19967274636310575 2.853854450462618 0.01882338737220583 0.1562682778763122 1.3986710308303527e-05 4.854284420100966 0.3523069939379109 AMLDSGIYPPGS(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 AMLDSGIYPPGSPGK 15 0 O95295 O95295 SNAPIN SNARE-associated protein Snapin 1 AMLDSGIYPPGS(1)PGK;AMLDSGIYPPGS(1)PGK;AMLDS(0.326)GIY(0.298)PPGS(0.376)PGK;AMLDS(0.001)GIY(0.001)PPGS(0.999)PGK;AMLDSGIY(0.007)PPGS(0.993)PGK;AMLDS(0.001)GIY(0.002)PPGS(0.998)PGK 149.6 5.9637999999999995e-06 92432600.0 290357.0 312437.0 277479.0 364398.0 392057.0 338926.0 378407.0 381276.0 330539.0 282891.0 True False 339508.7052878435 343453.6805358016 284095.15170496696 343981.9614542564 315236.24525472394 321152.12391487684 342561.5495305654 371267.9089953153 335372.5075566481 334176.89893607644 1.0159550416822407 1.0277600924218873 0.8501340236546708 1.029340934545136 0.9433214751179566 0.9610243105891917 1.0250904554479476 1.1109921427164058 1.0035777716065297 1.0 18.35025248030066 -7.376107071491839 4.579441250768236 1.0469956040864505 0.9698591110034191 0.2265277976784339 0.05694979542069217 0.3065182539510704 10.219805735443602 0.024379799690955797 0.016031296440213068 4.2062291471315046e-08 7.376107071491839 -0.07713649308303139 AMLDSGIYPPGS(ph)PGK ddPTM_PC-9_Lapatinib_30min_R1 7 AMLDSGIYPPGSPGK 15 0 O95295 O95295 SNAPIN SNARE-associated protein Snapin 1 AMLDS(0.001)GIYPPGS(0.999)PGK;AMLDS(0.001)GIY(0.001)PPGS(0.998)PGK;AMLDS(0.062)GIYPPGS(0.937)PGK;AMLDSGIY(0.001)PPGS(0.999)PGK;AMLDSGIYPPGS(1)PGK;AMLDS(0.001)GIYPPGS(0.999)PGK;AMLDS(0.001)GIY(0.094)PPGS(0.905)PGK 161.26 9.4722e-05 98276000.0 628661.0 561252.0 547096.0 583966.0 610355.0 589730.0 556259.0 511898.0 597052.0 537270.0 True False 619696.1788576918 559952.4554772193 502115.8787316316 626912.8076934683 574455.1189040996 564508.6226277737 585059.3692238093 535682.6498555244 529805.7165237142 630136.4036327255 0.9834318018847253 0.8886210227644413 0.7968368052328706 0.9948842886704002 0.9116361403537008 0.8958514686239221 0.928464640117524 0.8501058608379443 0.8407794145353188 1.0 19.26530463248401 -7.736562577385279 24.97100349409485 0.8840819054406072 0.9110387737097168 0.00134579924857825 0.06543441354670294 921.2743492641661 924764.6882756471 0.030387477684966198 0.017535325011804877 1.8341608642878675e-08 7.736562577385279 0.02695686826910959 AMLPGS(ph)PLFTR ddPTM_PC-9_AZD4547_30min_R2 1 AMLPGSPLFTR 11 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 AMLPGS(1)PLFTR 127.52 0.00035618 6061700.0 28899.0 31899.0 32024.0 53281.0 44674.0 44965.0 40679.0 48153.0 45737.0 53932.0 True False 38088.28086345828 42209.72793105623 31599.340835890125 40997.88863324407 38471.7862293715 42153.3314417989 44299.352194335006 40712.060295859905 48154.5644460639 52043.857095623214 0.73184969348979 0.8110415001236714 0.607167542901957 0.7877565369130165 0.7392185817182044 0.809957866196353 0.8511927183440924 0.7822644701574917 0.9252689391869383 1.0 15.6674402671724 -8.213848271592349 0.4773591188536484 1.00755018556062 0.7230932173254917 0.6798961604301809 0.057784860388375714 0.5542898834199215 0.3305865898301242 0.06442424226970273 0.037230730880913894 6.111555055254359e-09 8.213848271592349 -0.2844569682351282 AMLPGS(ph)PLFTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AMLPGSPLFTR 11 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 AMLPGS(1)PLFTR 85.522 0.0325 0.0 11419.0 12993.0 15926.0 19019.0 23010.0 22337.0 18856.0 16287.0 16797.0 17987.0 True False 13352.011164469539 14282.859172254446 16305.736239691349 17953.427090429956 18501.355678667074 21165.60839795883 17069.823174381967 15859.483507502939 17042.624348197995 21247.900714986343 0.6283920159252364 0.6722009559363487 0.7674045760290455 0.8449506297705559 0.8707380520475557 0.9961270377656899 0.8033651607917417 0.7464023726502589 0.802085089572057 1.0 14.375032690085089 -5.399137295764036 1.754167787409892 0.8602297037780806 0.6298961989872915 0.5658137952427607 0.07613097383656087 0.33039466461772005 1.8686324260744054 0.023872241658905863 0.08289105962759567 3.988987764904317e-06 5.399137295764036 -0.23033350479078907 AMLPGS(ph)PLFTR ddPTM_PC-9_Lapatinib_30min_R1 6 AMLPGSPLFTR 11 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 AMLPGS(1)PLFTR;AMLPGS(0.998)PLFT(0.002)R;AMLPGS(1)PLFTR;AMLPGS(1)PLFTR;AMLPGS(0.999)PLFT(0.001)R;AMLPGS(1)PLFTR 140.63 0.00012305 37415900.0 382104.0 337326.0 316104.0 270853.0 248699.0 252307.0 220218.0 234618.0 228999.0 193208.0 True False 376655.12689070805 336544.94237224804 290115.14931672666 290772.43315912026 234071.01378104664 241516.4177663434 231619.81050505032 245519.20879511812 203206.72115362468 226603.74536652205 1.662175204922073 1.4851693727652238 1.2802751730668775 1.283175759909917 1.0329529787887954 1.0658094700760603 1.0221358439173853 1.0834737457582666 0.8967491725476396 1.0 17.78981218103678 -4.593354760752152 0.4893258002460012 0.9777315469549965 2.2883551340847164 0.9424934285947526 0.05509466450901673 1.1376327782822047 0.1833438138103955 0.034147357249356164 0.8948512941553474 2.5506169371074833e-05 4.593354760752152 1.3106235871297198 AMLPLYDT(ph)GSGTIYDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AMLPLYDTGSGTIYDLR 17 0 H0YNP1;O94923 H0YNP1 GLCE D-glucuronyl C5-epimerase 1 AMLPLYDT(0.992)GS(0.006)GT(0.001)IYDLR 87.863 0.006903 2712300.0 3912.2 4926.7 4089.8 5610.4 6245.0 4757.8 4094.7 5358.4 5564.6 3702.6 True False 4574.458190527869 5415.790216574 4187.316342652872 5296.067477162217 5021.337080107601 4508.292592371782 3706.8203729392126 5217.747677694098 5645.971747811073 4373.852070234528 1.0458648616990343 1.238219795641969 0.9573520721354315 1.2108474159891374 1.148035415801878 1.0307373271840092 0.8474955973397728 1.1929410491960968 1.2908465254766457 1.0 12.094688711918682 -6.751674164368523 24.925841478537393 1.0704061309619033 1.1226321060452475 0.03117547517870134 0.13222216432249578 882.1349282731758 2251655.669175345 0.04560015340834298 0.045041024943038965 1.771437506137629e-07 6.751674164368523 0.052225975083344256 AMS(ph)CPSGEPHASTGR ddPTM_PC-9_AZD4547_30min_R2 2 AMSCPSGEPHASTGR 15 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5 Q8NEV8-2 EXPH5 Exophilin-5 1 AMS(0.999)CPS(0.001)GEPHASTGR;AMS(0.937)CPS(0.063)GEPHASTGR 101.72 0.0014252000000000002 2254380.0 2697.0 2119.9 6338.400000000001 15839.9 5617.8 6660.9 3223.8 11551.599999999999 5457.8 8237.2 True False 3554.5898989150824 2805.1162180960578 6254.34867456301 12188.255779015468 4837.865440286591 6244.392870025094 3510.7119546718727 9766.56564936049 5746.28816568047 7948.818135208546 0.4471847057577477 0.35289726980556496 0.7868274966387717 1.5333418845033993 0.6086270132232261 0.7855750079834058 0.441664646863853 1.228681482357786 0.7229110124218121 1.0 12.956524654841974 -5.333173357279467 5.084947629889773 0.8943561953156094 0.40045362688414377 0.30894853370831954 0.2946630865222404 0.24380376074815993 11.77786917987369 0.0785265102274884 0.17175621583838613 4.643298917148328e-06 5.333173357279467 -0.4939025684314656 AMS(ph)EVTSLHEDDWR ddPTM_PC-9_AZD4547_30min_R2 1 AMSEVTSLHEDDWR 14 0 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 1 AMS(0.887)EVT(0.03)S(0.083)LHEDDWR 60.968 0.037315 3650000.0 10122.0 15459.0 21271.0 19877.0 16905.0 14203.0 14858.0 22394.0 13635.0 11297.0 True False 13340.585449320903 20455.819432778408 20988.9326417755 15294.664746588705 14558.032551540611 13314.884164747471 16180.333216240067 18933.521862926245 14355.7182635958 10901.49546853919 1.2237390262483459 1.8764232386109048 1.925325997919076 1.4029877635346304 1.335416098970447 1.2213814336916546 1.4842306051435938 1.7367820697230776 1.3168577013149443 1.0 13.412238437217258 -12.756599401913617 0.16570972767050787 2.369789408167538e-15 1.6673916932523967 0.2933365597187617 0.24220739060512197 93.87811396189221 1.4970627407053236 34.18952412481214 1.0944201485856095 1.7514615114278181e-13 12.756599401913617 1.6673916932523942 AMS(ph)LNTLNVDAPR ddPTM_PC-9_AZD4547_30min_R2 5 AMSLNTLNVDAPR 13 0 Q6P597;Q6P597-3;Q6P597-2 Q6P597 KLC3 Kinesin light chain 3 1 AMS(1)LNTLNVDAPR;AMS(1)LNTLNVDAPR;AMS(0.994)LNT(0.006)LNVDAPR;AMS(1)LNTLNVDAPR;AMS(0.999)LNT(0.001)LNVDAPR 129.17 8.453100000000001e-05 459810200.0 796685.0 937013.0 1284384.0 1757707.0 1389353.0 1333002.0 1124944.0 1387255.0 1066487.0 1193631.0 True False 1050014.2579225646 1239884.1279620929 1267352.2289584011 1352494.807452442 1196465.317928458 1249649.174215076 1225061.8366947095 1172886.6156985683 1122859.3255436383 1151842.3420030028 0.9115954672204847 1.0764356220886873 1.100282723375607 1.1742013278488386 1.0387405240268022 1.084913384970717 1.0635672887006231 1.018270099064921 0.9748376879348225 1.0 20.135511831264168 -7.881993367226914 2.8028777517548504 0.9883646827051585 1.0707204514171043 0.1999755284875402 0.06207719340906098 0.4293176796746123 6.60530012049722 0.04344684495682285 0.017613425449223855 1.3122199397772574e-08 7.881993367226914 0.08235576871194572 AMS(ph)LNTLNVDAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 AMSLNTLNVDAPR 13 0 Q6P597;Q6P597-3;Q6P597-2 Q6P597 KLC3 Kinesin light chain 3 1 AMS(0.999)LNT(0.001)LNVDAPR;AMS(0.998)LNT(0.002)LNVDAPR;AMS(0.998)LNT(0.002)LNVDAPR;AMS(1)LNTLNVDAPR;AMS(0.993)LNT(0.007)LNVDAPR;AMS(0.994)LNT(0.006)LNVDAPR 111.66 0.00047653 401945900.0 848313.5 927147.8 1062016.8 1197847.5 1342365.0 1124001.3 1180085.3 1107112.3 1102190.7 923013.5 True False 991916.2205946443 1019188.9062776512 1087339.3082331412 1130735.9880489898 1079338.214497783 1065056.693136799 1068299.0773062934 1078051.7752074443 1118308.153847556 1090348.5409791525 0.9097239857852112 0.9347368001817119 0.9972401185190664 1.0370408594609286 0.9899020120011514 0.9768038871133435 0.9797776006073633 0.9887221697378844 1.0256428213709492 1.0 20.056357950165747 -5.17437990181179 3.446335919572044 0.9987051094740259 0.9148265987126636 0.7490939818189044 0.01809458965553682 0.12750174315541477 2.8429061441331527 0.005155212511988215 0.01645062400021549 6.692988798912103e-06 5.17437990181179 -0.08387851076136232 AMS(ph)LNTLNVDAPR ddPTM_PC-9_Lapatinib_30min_R1 4 AMSLNTLNVDAPR 13 0 Q6P597;Q6P597-3;Q6P597-2 Q6P597 KLC3 Kinesin light chain 3 1 AMS(0.999)LNT(0.001)LNVDAPR;AMS(0.992)LNT(0.008)LNVDAPR;AMS(0.997)LNT(0.003)LNVDAPR;AMS(1)LNTLNVDAPR 119.17 0.00020437 256391000.0 843689.0 822074.0 840141.0 672604.0 787594.0 778489.0 719273.0 685885.0 784891.0 573274.0 True False 831657.8401463861 820170.5381610777 771067.8500180449 722069.5419011689 741269.269389381 745194.8402164945 756513.4365101823 717753.7210462972 696488.310311354 672363.6470604109 1.2369167247253967 1.219831770719434 1.1468018138535165 1.073927100398829 1.1024826708437123 1.108321134663516 1.1251551743132993 1.0675082214577376 1.0358803801431213 1.0 19.358882198381124 -1.5228787452803376 0.225414947609031 1.0221358106474623 2.2476098703032235 0.8377989515159222 0.02861635591970139 22.159958103430778 0.2870459821956599 0.048556696657338645 9.954855533143563 0.029999999999999995 1.5228787452803376 1.2254740596557612 AMS(ph)TTSISSPQPGK ddPTM_PC-9_AZD4547_30min_R2 8 AMSTTSISSPQPGK 14 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3;H0Y5J4;Q9UJU6-5;Q9UJU6 B4DDD6;H0Y5J4 DBNL Drebrin-like protein 1 AMS(0.973)T(0.027)T(0.001)SISSPQPGK;AMS(0.93)T(0.056)T(0.013)SISSPQPGK;AMS(0.98)T(0.014)T(0.005)S(0.001)ISSPQPGK;AMS(0.963)T(0.03)T(0.006)S(0.001)ISSPQPGK;AMS(0.941)T(0.059)T(0.001)SISSPQPGK;AMS(0.925)T(0.059)T(0.014)S(0.001)ISSPQPGK;AMS(0.956)T(0.042)T(0.001)SISSPQPGK;AMS(0.75)T(0.204)T(0.042)S(0.003)IS(0.001)SPQPGK 127.3 7.826e-05 313844100.0 269755.0 241363.0 352402.0 358896.0 482977.0 319055.0 265166.0 333103.0 278890.0 303359.0 True False 355531.4787474365 319378.8696392842 347728.91922462353 276158.07208792557 415923.98033986636 299104.440412835 288765.26030539203 281629.5852954511 293631.55603478034 292738.49374529347 1.214501974778821 1.0910040068634432 1.1878482900413372 0.9433609791276912 1.4208038547255573 1.0217461891878163 0.9864273625614864 0.9620517674060726 1.0030507169660574 1.0 18.159252940320137 -6.975515960920175 24.98324600218251 0.9874866163221887 1.1618660497871238 0.3874927717755413 0.11149312930719073 239.31791260952423 244196.68938397837 0.037604366591943536 0.03316259639072498 1.057996032470812e-07 6.975515960920175 0.17437943346493512 AMS(ph)TTSISSPQPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 AMSTTSISSPQPGK 14 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3;H0Y5J4;Q9UJU6-5;Q9UJU6 B4DDD6;H0Y5J4 DBNL Drebrin-like protein 1 AMS(0.915)T(0.051)T(0.028)S(0.002)IS(0.002)S(0.002)PQPGK;AMS(0.941)T(0.055)T(0.004)SISSPQPGK;AMS(0.97)T(0.029)T(0.001)SISSPQPGK;AMS(0.966)T(0.032)T(0.001)S(0.001)ISSPQPGK;AMS(0.957)T(0.041)T(0.002)SISSPQPGK 138.21 6.6849e-05 205439900.0 240426.0 224463.0 185128.0 224139.0 243833.0 217147.0 165973.0 236582.0 170442.0 137788.0 True False 281125.37317004584 246746.2032157126 189542.15362184978 211581.2184984427 196055.67401983668 205759.42905455356 150250.83589953836 230371.97317934892 172934.39180541586 162767.87367079177 1.7271551617037126 1.515939218538741 1.1644936396061218 1.299895450661099 1.2045108755083425 1.264128015032714 0.9230988432240019 1.415340558206779 1.0624602257518367 1.0 17.312456450026538 -1.5228787939101123 0.5821132329340549 1.1451007782448919 35.28465454361721 0.6495548113940166 0.13778743559141715 94.32289669069662 0.7774134152093382 0.06107119356788246 4072.8164106415134 0.029999996640774358 1.5228787939101123 34.13955376537231 AMS(ph)TTSISSPQPGK ddPTM_PC-9_Lapatinib_30min_R1 7 AMSTTSISSPQPGK 14 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3;H0Y5J4;Q9UJU6-5;Q9UJU6 B4DDD6;H0Y5J4 DBNL Drebrin-like protein 1 AMS(0.943)T(0.055)T(0.002)S(0.001)ISSPQPGK;AMS(0.898)T(0.034)T(0.06)S(0.008)IS(0.001)SPQPGK;AMS(0.979)T(0.02)T(0.001)SISSPQPGK;AMS(0.989)T(0.011)TSISSPQPGK;AMS(0.941)T(0.055)T(0.003)S(0.001)ISSPQPGK;AMS(0.915)T(0.075)T(0.007)S(0.002)IS(0.001)SPQPGK;AMS(0.33)T(0.33)T(0.33)S(0.009)ISSPQPGK 206.45 8.320600000000001e-11 215565700.0 373878.0 285572.0 343300.0 435362.0 289149.0 311955.0 333770.0 322156.0 427533.0 442355.0 True False 368546.43115917227 284910.7755794916 315075.199176322 467379.97380505735 272141.82430880656 298613.4118526231 351050.9774508471 337124.54384829884 379379.7314179223 518815.472349012 0.7103612956848127 0.5491562814993102 0.6072972298797751 0.9008597443883604 0.5245445419671952 0.5755676685982547 0.676639375964277 0.6497966267696659 0.7312421306562539 1.0 18.98486197937018 -8.817976185430567 1.642514595273126 0.999952739201478 0.6457857927032489 0.5241276224775688 0.1003358520445564 0.9235000316949769 3.919228028901809 0.09692174346874488 0.02765035062452202 1.5206309113527371e-09 8.817976185430567 -0.3541669464982291 AMSEVTS(ph)LHEDDWR ddPTM_PC-9_AZD4547_30min_R2 1 AMSEVTSLHEDDWR 14 0 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 1 AMS(0.018)EVT(0.346)S(0.635)LHEDDWR 68.57600000000001 0.021976 3365200.0 11527.0 15484.0 12941.0 16381.0 13862.0 12544.0 14587.0 17961.0 14573.0 11230.0 True False 15192.346223505438 20488.900193876758 12769.393884500816 12604.613533927126 11937.500575537179 11759.621697007124 15885.214741236627 15185.540152720285 15343.299028630843 10836.841118145969 1.401916486351941 1.8906709040486624 1.1783317431053635 1.1631261727018471 1.1015664477675315 1.08515217384852 1.4658528779791102 1.4012884370236405 1.415846081100049 1.0 13.403656659549728 -5.278574132950438 24.76365877706969 1.2375170505817776 1.6462937114368907 0.4545361951874526 0.18367061379497315 577.4588219525295 834560.3738130063 0.049299640211139514 0.10304016169576195 5.265333293381734e-06 5.278574132950438 0.4087766608551131 AMSEVTS(ph)LHEDDWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AMSEVTSLHEDDWR 14 0 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 1 AMSEVT(0.046)S(0.954)LHEDDWR;AMS(0.001)EVT(0.06)S(0.939)LHEDDWR 78.22800000000001 0.0098446 1695400.0 17866.2 20607.0 21228.0 16191.3 30227.0 17510.3 16168.4 19067.0 16408.5 13857.400000000001 True False 20890.59478646515 22652.726773081475 21734.1560276383 15284.15395390285 24304.23633633507 16592.029042878574 14636.812102920952 18566.511453156414 16648.443270667787 16369.636924881956 1.2761794829249578 1.3838258525238993 1.3277115508042967 0.9336892457688439 1.484714441002199 1.0135856475630551 0.8941439672784007 1.1342042305736906 1.0170319199543176 1.0 13.998734703042567 -6.805934928129897 23.603475153584043 1.0128269953374829 1.2701992618273288 0.4693269920972024 0.14300736955897692 71.94013655424882 38161.15362209146 0.050102895226560376 0.04418697276415627 1.563381872098791e-07 6.805934928129897 0.2573722664898459 AMSEVTS(ph)LHEDDWR ddPTM_PC-9_Lapatinib_30min_R1 1 AMSEVTSLHEDDWR 14 0 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 1 AMS(0.008)EVT(0.411)S(0.581)LHEDDWR 64.565 0.028391000000000003 2430100.0 15647.0 14741.0 12109.0 8611.7 11402.0 10125.0 7267.2 9751.3 12351.0 6364.3 True False 15423.870910691634 14706.868120184343 11113.444762091716 9245.033145789057 10731.356777194493 9691.977352527787 7643.460057317306 10204.380996870823 10959.900318204098 7464.36077510331 2.0663351324250754 1.9702783082561808 1.488867579814683 1.2385565789672193 1.4376792736208501 1.2984336696123382 1.0239939209277458 1.3670803574911061 1.4682972391634446 1.0 12.865803002346109 -5.325401080971465 2.2475606497239773 1.2745790099744758 2.075269996021489 0.8062369340953094 0.1465968871779379 0.13548197500930195 1.2872762982587187 0.0412601067951814 0.13261101452858648 4.72714494572169e-06 5.325401080971465 0.800690986047013 AMSLNT(ph)LNVDAPR ddPTM_PC-9_AZD4547_30min_R2 1 AMSLNTLNVDAPR 13 0 Q6P597;Q6P597-3;Q6P597-2 Q6P597 KLC3 Kinesin light chain 3 1 AMS(0.094)LNT(0.906)LNVDAPR 138.28 0.00015496 17668000.0 22901.0 17374.0 23807.0 37180.0 28718.0 28134.0 18824.0 32024.0 23408.0 26259.0 True False 30183.041629608542 22989.805732912337 23491.303624782526 28608.725425273813 24731.001408763284 26374.776532493524 20499.29953308003 27075.42663831161 24645.299091620873 25339.68040261756 1.191137423599497 0.907265023379597 0.9270560343119364 1.1290089287123986 0.9759792158313331 1.040848823403828 0.8089801926216273 1.0684991368523633 0.9725970769968765 1.0 14.629110708113949 AMSLNT(ph)LNVDAPR ddPTM_PC-9_Lapatinib_30min_R1 2 AMSLNTLNVDAPR 13 0 Q6P597;Q6P597-3;Q6P597-2 Q6P597 KLC3 Kinesin light chain 3 1 AMS(0.347)LNT(0.653)LNVDAPR;AMS(0.039)LNT(0.961)LNVDAPR 178.67 0.00022238 88778000.0 80190.0 83787.0 96715.0 81993.0 104753.0 94335.0 80630.0 81700.0 89018.0 70008.0 True False 79046.47589495502 83592.99634935799 88763.46603069615 88023.03874063001 98591.63449232203 90300.51195562562 84804.6268743801 85496.08026051355 78991.85543890316 82108.78952020373 0.9627041922899716 1.0180761016917568 1.0810470663296645 1.0720294289440355 1.2007439772091941 1.0997666934720336 1.0328325063605162 1.0412536923282292 0.962038971716498 1.0 16.325249046357328 -7.90813699320563 1.9483470955136093 0.9839201422107596 1.0741173035615734 0.24364194371651626 0.05886363288245294 0.5394015513689345 3.838355446633207 0.05191654451139196 0.01864129094713153 1.2355576295066245e-08 7.90813699320563 0.09019716135081379 AMST(ph)TSISSPQPGK ddPTM_PC-9_Lapatinib_30min_R1 1 AMSTTSISSPQPGK 14 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3;H0Y5J4;Q9UJU6-5;Q9UJU6 B4DDD6;H0Y5J4 DBNL Drebrin-like protein 1 AMS(0.3)T(0.659)T(0.02)S(0.02)IS(0.001)SPQPGK 118.52 0.00043729 35649000.0 44928.0 37271.0 44741.0 49571.0 36886.0 40856.0 44390.0 41405.0 51209.0 51845.0 True False 44287.31848121387 37184.7012894234 41062.56768525441 53216.61670400836 34716.4380006662 39108.68411998768 46688.29699806187 43328.82745638392 45441.30316532378 60806.33917087986 0.7283339053968745 0.6115267223196219 0.6753007703663776 0.8751820522274392 0.570934518901146 0.6431678777780594 0.767819566753673 0.7125708938770332 0.7473119379481672 1.0 15.891934114627162 -9.47865857928605 0.6385681203084835 1.0152603727583003 0.6882975170003006 0.5641447603657996 0.07971150859078549 3.145918087882 1.5053412269607112 0.200240289980223 0.031773680664977905 3.321554790498019e-10 9.47865857928605 -0.32696285575799966 AMSTSQS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 2 AMSTSQSPTR 10 0 Q15776 Q15776 ZKSCAN8 Zinc finger protein with KRAB and SCAN domains 8 1 AMS(0.001)T(0.006)S(0.019)QS(0.959)PT(0.015)R;AMST(0.005)S(0.016)QS(0.971)PT(0.007)R 102.05 0.0029648000000000005 16065600.0 63821.0 71205.0 80614.0 108541.0 79031.0 84505.0 63193.0 98816.0 59117.0 82908.0 True False 84114.75044073399 94220.62376033289 79545.00568774814 83518.54939173331 68058.90982436012 79220.88899119782 68817.05457893775 83546.25776578173 62241.803930252536 80005.41615523135 1.0513632011803984 1.1776780659139419 0.9942452587636081 1.0439111925833318 0.8506787802004318 0.9901940743297761 0.8601549480776994 1.044257523811641 0.7779698790577781 1.0 16.287810049496926 -5.771094830876292 1.5806042797037352 0.9245115742053556 1.1093508822946088 0.4065966691140379 0.08611953893489811 0.3567270803824224 1.8066830194883339 0.025627129436394787 0.05617738252068651 1.6939678717374892e-06 5.771094830876292 0.1848393080892532 AMSTSQS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AMSTSQSPTR 10 0 Q15776 Q15776 ZKSCAN8 Zinc finger protein with KRAB and SCAN domains 8 1 AMST(0.001)S(0.001)QS(0.669)PT(0.329)R;AMS(0.016)T(0.305)S(0.153)QS(0.345)PT(0.181)R 72.289 0.027254 15973800.0 26709.0 24805.6 24815.5 24177.0 34427.0 31411.0 34595.0 27957.0 27456.0 21161.2 True False 31230.306173204026 27268.13603350074 25407.19563330782 22822.44107289156 27681.27648628734 29763.75186409477 31317.91115388968 27223.158372890033 27857.49205835115 24997.558048032966 1.2493342795002134 1.0908319917131444 1.016387104071835 0.9129868217142689 1.1073592241729209 1.1906663765678045 1.2528388210445243 1.0890327095382901 1.1144085356186713 1.0 14.609499547874265 -6.517564557938833 24.906594369833577 1.1433742569794416 1.0585116104434056 0.06849589725728777 0.09948721825485032 485.8266142727512 2276990.850964735 0.0338107688893363 0.0347701044999528 3.0369346176119394e-07 6.517564557938833 -0.08486264653603603 AMSTSQS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 1 AMSTSQSPTR 10 0 Q15776 Q15776 ZKSCAN8 Zinc finger protein with KRAB and SCAN domains 8 1 AMST(0.019)S(0.019)QS(0.942)PT(0.021)R 80.737 0.015186000000000002 4436300.0 22176.0 18262.0 21204.0 13156.0 11483.0 17723.0 14355.0 15716.0 17162.0 10263.0 True False 21859.76617341967 18219.715461013944 19460.688969806986 14123.536127129466 10807.592516446613 16965.028604330855 15098.231660445566 16446.22273407873 15229.03483612816 12036.945875412097 1.8160558666357947 1.5136493633514967 1.6167464048799447 1.173348810679597 0.8978683320761052 1.4094130504470712 1.2543241297850118 1.3663119286490666 1.2651909374483898 1.0 13.555181764227049 -5.756603363145483 23.18935483324387 1.209470327539199 1.6353008055130946 0.6234497480479695 0.16117914160877772 34.19208858792827 163948.52307344537 0.04526427057345776 0.0751093557077779 1.7514455362915922e-06 5.756603363145483 0.4258304779738957 AMSTT(ph)SISSPQPGK ddPTM_PC-9_Lapatinib_30min_R1 1 AMSTTSISSPQPGK 14 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3;H0Y5J4;Q9UJU6-5;Q9UJU6 B4DDD6;H0Y5J4 DBNL Drebrin-like protein 1 AMS(0.07)T(0.218)T(0.71)S(0.001)ISSPQPGK 217.68 4.0009e-15 23570000.0 118290.0 81351.0 118740.0 134190.0 80037.0 99228.0 104030.0 104000.0 134570.0 138200.0 True False 116603.16290827094 81162.63675769068 108977.65554965507 144058.78024471772 75329.38101879631 94984.24975176563 109416.16437730058 108832.21967066597 119413.30951507787 162087.6858600749 0.7193832294510683 0.5007328985358935 0.6723376607630266 0.888770664349413 0.46474462645993814 0.586005341786189 0.6750430410349373 0.6714403940877861 0.7367204293246776 1.0 17.306414964900974 -8.84726168193679 1.2183715703142664 0.9998758464869546 0.6398388278899126 0.47927388177942254 0.11106519829297105 1.0051529343025987 2.502776177218124 0.10788643443437462 0.03284694607059074 1.4214720282717296e-09 8.84726168193679 -0.36003701859704196 AMSTTS(ph)ISSPQPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AMSTTSISSPQPGK 14 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3;H0Y5J4;Q9UJU6-5;Q9UJU6 B4DDD6;H0Y5J4 DBNL Drebrin-like protein 1 AMST(0.005)T(0.025)S(0.426)IS(0.426)S(0.117)PQPGK 131.08 1.538e-05 69564000.0 34748.0 27794.0 35656.0 40254.0 48322.0 41723.0 40477.0 58142.0 43310.0 32556.0 True False 40630.150095716555 30553.20463585316 36506.17426613301 37998.69888522884 38853.65098237945 39534.97243085627 36642.725531897464 56615.83410654116 43943.326815529916 38458.1450868458 1.0564771130788018 0.7944534133629747 0.9492442805989508 0.9880533447315403 1.0102840606233223 1.0279999813194005 0.9527949267743212 1.472141570496753 1.1426273086311765 1.0 15.23100155984182 -7.7160288541524755 24.999984398592513 1.2305389135909057 0.9656903607916528 0.41355917678749166 0.12791437705139447 100.58059574680526 55372.78089777619 0.05740661804361335 0.033143550154266475 1.9229639645912536e-08 7.7160288541524755 -0.2648485527992529 AMSTTS(ph)ISSPQPGK ddPTM_PC-9_Lapatinib_30min_R1 2 AMSTTSISSPQPGK 14 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3;H0Y5J4;Q9UJU6-5;Q9UJU6 B4DDD6;H0Y5J4 DBNL Drebrin-like protein 1 AMS(0.002)T(0.001)T(0.196)S(0.762)IS(0.017)S(0.021)PQPGK;AMS(0.004)T(0.002)T(0.129)S(0.854)IS(0.01)S(0.002)PQPGK 103.85 0.0051412 0.0 32964.0 30664.0 31663.0 24631.0 25151.0 26456.0 24442.0 24455.0 21489.0 20977.9 True False 32493.92731514275 30592.99939199054 29059.79036271454 26442.44590660731 23671.667628768526 25324.53855194818 25707.487164375485 25591.26857736671 19068.68253079816 24603.902063705285 1.3206818670879252 1.24342062949113 1.181104943739083 1.074725701563175 0.9621103013447629 1.0292895202710934 1.0448540681804357 1.040130484632271 0.775026761260261 1.0 14.586599517940307 -5.089879041144601 0.5543053327419873 0.9542672016538859 1.504772999005371 0.7504480800560375 0.07272414256842598 1.5337595797133494 0.45709246913367907 0.0437515342351728 0.5211690154804915 8.130569356698776e-06 5.089879041144601 0.5505057973514852 AMSTTSIS(ph)SPQPGK ddPTM_PC-9_AZD4547_30min_R2 7 AMSTTSISSPQPGK 14 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3;H0Y5J4;Q9UJU6-5;Q9UJU6 B4DDD6;H0Y5J4 DBNL Drebrin-like protein 1 AMS(0.002)T(0.005)T(0.029)S(0.168)IS(0.56)S(0.238)PQPGK;AMSTT(0.001)S(0.032)IS(0.695)S(0.272)PQPGK;AMST(0.001)T(0.002)S(0.093)IS(0.541)S(0.363)PQPGK;AMSTTS(0.18)IS(0.638)S(0.182)PQPGK;AMSTTS(0.241)IS(0.541)S(0.218)PQPGK;AMSTTS(0.031)IS(0.748)S(0.221)PQPGK;AMSTT(0.002)S(0.017)IS(0.574)S(0.406)PQPGK 139.48 9.0981e-05 338193200.0 223931.0 227166.0 331339.0 481851.0 366924.0 315044.0 418719.0 665246.0 538800.0 423451.0 True False 295136.3999458488 300592.96702675044 326945.2283669436 370767.6964737394 315982.9361692681 295344.24887690716 455984.17983381497 562447.5165322964 567279.8680179997 408626.1093784527 0.7222651543112866 0.7356186012782496 0.8001085120680342 0.9073519483072229 0.7732813173634426 0.7227738073960699 1.1158958504325556 1.3764355816318645 1.388261432635496 1.0 18.640421863205418 -7.4218347458090355 3.660376604991245 1.2833305993948096 0.7825668358870215 0.7893317584663067 0.11324365517399824 0.10091287983452493 2.4708941143341785 0.051263894894347226 0.03235115565535162 3.785866140007639e-08 7.4218347458090355 -0.5007637635077882 AMSTTSIS(ph)SPQPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AMSTTSISSPQPGK 14 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3;H0Y5J4;Q9UJU6-5;Q9UJU6 B4DDD6;H0Y5J4 DBNL Drebrin-like protein 1 AMSTT(0.002)S(0.009)IS(0.779)S(0.211)PQPGK;AMST(0.001)T(0.009)S(0.097)IS(0.584)S(0.309)PQPGK;AMSTT(0.002)S(0.041)IS(0.734)S(0.223)PQPGK 140.31 4.7355e-05 167487900.0 116472.0 106745.0 122321.0 127195.0 164755.0 134007.0 143236.0 194222.0 146684.0 102619.0 True False 136188.40917314118 117341.93814687166 125237.59654497581 120068.67652175388 132472.44045366373 126979.43701415889 129667.6491411631 189123.878295219 148828.976001136 121223.01236844312 1.1234534310961726 0.9679840143736456 1.0331173437955068 0.9904775848732353 1.0927994434837942 1.0474862365919417 1.0696619941026833 1.5601318149098553 1.227728738078112 1.0 16.887304073234375 -7.558618586884226 24.99953546660534 1.2993379306912995 1.040311611112448 0.3444734536149947 0.134249768043585 155.11896086505544 108501.97055963297 0.0587165200175018 0.03390012897894858 2.763003360428262e-08 7.558618586884226 -0.2590263195788516 AMSTTSIS(ph)SPQPGK ddPTM_PC-9_Lapatinib_30min_R1 4 AMSTTSISSPQPGK 14 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3;H0Y5J4;Q9UJU6-5;Q9UJU6 B4DDD6;H0Y5J4 DBNL Drebrin-like protein 1 AMSTT(0.001)S(0.029)IS(0.737)S(0.233)PQPGK;AMSTT(0.006)S(0.004)IS(0.778)S(0.212)PQPGK;AMSTTS(0.022)IS(0.68)S(0.298)PQPGK;AMSTT(0.001)S(0.023)IS(0.709)S(0.267)PQPGK 158.52 1.5819000000000002e-05 211633300.0 226218.0 220525.0 207570.0 178152.0 203567.0 155812.0 192457.0 156044.0 168856.0 183770.0 True False 222992.08983669948 220014.3879115152 190504.39584337064 191253.89237765045 191593.58928812054 149148.28397551217 202421.48176066653 163294.37390662899 149837.65914749197 215534.39964186738 1.0346009277740529 1.0207854907480745 0.8838700279858498 0.8873474150550377 0.8889234832419931 0.6919929450859696 0.9391609046955414 0.7576255770677879 0.6951913912417818 1.0 17.717558618610347 -5.307587343641564 0.8804144463253176 0.8125425018228912 1.0922590239670287 0.3862768490397068 0.09473918972323854 1.1489270047609128 1.1679863954719665 0.03562309992310524 0.26646762775891353 4.925072822116788e-06 5.307587343641564 0.27971652214413745 AMSTTSISS(ph)PQPGK ddPTM_PC-9_Lapatinib_30min_R1 3 AMSTTSISSPQPGK 14 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3;H0Y5J4;Q9UJU6-5;Q9UJU6 B4DDD6;H0Y5J4 DBNL Drebrin-like protein 1 AMSTTS(0.001)IS(0.032)S(0.967)PQPGK;AMSTTS(0.006)IS(0.033)S(0.96)PQPGK;AMSTTSIS(0.041)S(0.959)PQPGK 247.73 3.6584000000000004e-35 64342000.0 379953.0 332333.0 320733.0 270058.0 319396.0 244678.0 295972.0 260794.0 261052.0 277620.0 True False 374534.8005451525 331563.5033569792 294363.5708051827 289918.9662070793 300609.75523669616 234213.692312276 311295.98195788206 272911.44131530414 231649.57476057136 325606.2470946022 1.1502690869328884 1.018295890559637 0.9040476754724481 0.8903974318491676 0.9232309205337712 0.7193157207583525 0.956050397483429 0.8381640209624478 0.7114408179437278 1.0 18.312768853911805 -4.311488421014846 0.7766402099067289 0.8467024309431341 1.598832911910149 0.5308879916179449 0.08696206036804985 3.7126621777184217 1.028314041178624 0.03169040299862467 2.8670011004963833 4.881031146834187e-05 4.311488421014846 0.7521304809670148 AMT(ph)LSPQEEVAAGQMASSSR ddPTM_PC-9_AZD4547_30min_R2 5 AMTLSPQEEVAAGQMASSSR 20 0 A0A494BZT8;Q9Y6A5 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 AMT(0.79)LS(0.209)PQEEVAAGQMAS(0.001)SSR;AMT(0.704)LS(0.296)PQEEVAAGQMASSSR;AMT(0.553)LS(0.447)PQEEVAAGQMASSSR;AMT(0.865)LS(0.135)PQEEVAAGQMASSSR;AMT(0.649)LS(0.351)PQEEVAAGQMASSSR 180.76 3.1943e-09 84421000.0 115450.6 89604.6 138895.1 195412.0 169322.6 152581.0 110295.6 166264.1 119093.9 141224.0 True False 152161.48927834124 118567.5346365442 137053.26022155382 150362.78248530425 145815.07971082494 143040.08594954136 120111.69472911098 140571.80371393054 125388.96041898442 136279.7907452402 1.1165374443727323 0.8700302076203867 1.00567559923657 1.103338812475803 1.0699684737806054 1.0496059992999165 0.8813610152487418 1.031494126496817 0.9200847736359167 1.0 17.05621211175744 -7.215236490415321 24.996982342848252 0.960859310345714 1.0315674078892814 0.20531349117447062 0.07445774005955129 774.3233358321228 418929.6439952117 0.028926726974693836 0.022406492293767993 6.092050707962726e-08 7.215236490415321 0.07070809754356733 AMT(ph)LSPQEEVAAGQMASSSR ddPTM_PC-9_Lapatinib_30min_R1 2 AMTLSPQEEVAAGQMASSSR 20 0 A0A494BZT8;Q9Y6A5 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 AMT(0.985)LS(0.015)PQEEVAAGQMASSSR;AMT(0.905)LS(0.095)PQEEVAAGQMASSSR 258.43 5.825199999999998e-66 25856600.0 64436.0 56850.0 68581.0 54525.0 59648.0 56081.0 51098.0 47718.0 64826.0 51685.0 True False 63517.13082388478 56718.36731785356 62942.53491031573 58534.95039006795 56139.62191248 53682.546361196146 53743.60441556579 49935.15248312351 57524.61323195683 60618.68338406649 1.047814424167783 0.9356581857527093 1.0383355658110525 0.965625564963256 0.9261108750381767 0.8855775705499157 0.8865848186615711 0.823758446991425 0.9489584732069101 1.0 15.887474897196174 -6.249266310324365 2.3033563656777236 0.8972297850075096 1.0003335426970585 0.392696246932827 0.05217697938200058 0.28055493241361823 2.9269504708197878 0.016548032240932112 0.021344102666388642 5.63292137931975e-07 6.249266310324365 0.10310375768954894 AMTLS(ph)PQEEVAAGQMASSSR ddPTM_PC-9_AZD4547_30min_R2 6 AMTLSPQEEVAAGQMASSSR 20 0 A0A494BZT8;Q9Y6A5 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 AMT(0.045)LS(0.934)PQEEVAAGQMAS(0.018)S(0.003)SR;AMT(0.05)LS(0.95)PQEEVAAGQMASSSR;AMT(0.022)LS(0.946)PQEEVAAGQMAS(0.03)S(0.001)S(0.001)R;AMTLS(1)PQEEVAAGQMASSSR;AMT(0.001)LS(0.999)PQEEVAAGQMASSSR;AMT(0.004)LS(0.996)PQEEVAAGQMASSSR 157.02 1.4113e-05 46849600.0 197564.0 161617.0 230883.0 324309.0 274033.0 247418.0 198665.0 266456.0 201407.0 235322.0 True False 260385.24241351866 213856.53465730956 227821.340563728 249544.57057410252 235988.24810389368 231946.91334742607 216345.80013489927 225281.34774974882 212052.96283946003 227083.44840644227 1.146650027735494 0.9417530698870721 1.003249431706555 1.0989113135513888 1.0392137769614687 1.0214170824651165 0.9527149673527753 0.9920641479185749 0.9338107393010867 1.0 17.792863029569403 -7.110013807951173 3.934362841580444 0.9691868113536035 1.0401102836899756 0.30685807600850146 0.05375267165960865 0.3276755944210826 8.886146652178049 0.02120868694111924 0.016296704491149963 7.762224370337556e-08 7.110013807951173 0.07092347233637208 AMTLS(ph)PQEEVAAGQMASSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 AMTLSPQEEVAAGQMASSSR 20 0 A0A494BZT8;Q9Y6A5 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 AMT(0.017)LS(0.983)PQEEVAAGQMASSSR;AMT(0.006)LS(0.991)PQEEVAAGQMAS(0.003)SSR;AMT(0.047)LS(0.945)PQEEVAAGQMAS(0.007)SSR;AMT(0.007)LS(0.992)PQEEVAAGQMAS(0.001)SSR;AMT(0.252)LS(0.748)PQEEVAAGQMASSSR 133.93 7.1828e-07 85424000.0 135996.8 116572.0 157920.7 153080.0 165344.0 146041.6 143258.0 149917.0 124924.0 112381.3 True False 159018.37218076276 128144.49776249092 161686.12840558967 144503.423892056 132946.03013183505 138382.92140445646 129687.56514189733 145981.83760019165 126750.77716701124 132755.1400801189 1.1978321297751164 0.965269575891032 1.217927443773632 1.0884958865234664 1.0014379108153624 1.0423921915260015 0.9768929855644741 1.0996322817488673 0.9547711455128293 1.0 17.018408195538072 -6.139677120608016 4.8250781441062065 1.0175260152490269 1.1167516369982164 0.3343336679014205 0.07311541233344487 0.2874578670818729 10.115764550702925 0.02056982622540221 0.02695704977957143 7.249747475175523e-07 6.139677120608016 0.09922562174918959 AMTLS(ph)PQEEVAAGQMASSSR ddPTM_PC-9_Lapatinib_30min_R1 12 AMTLSPQEEVAAGQMASSSR 20 0 A0A494BZT8;Q9Y6A5 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 AMT(0.044)LS(0.954)PQEEVAAGQMAS(0.002)S(0.001)SR;AMT(0.054)LS(0.946)PQEEVAAGQMASSSR;AMT(0.408)LS(0.592)PQEEVAAGQMASSSR;AMT(0.37)LS(0.629)PQEEVAAGQMASSSR;AMT(0.005)LS(0.995)PQEEVAAGQMASSSR;AMT(0.003)LS(0.997)PQEEVAAGQMASSSR;AMT(0.269)LS(0.731)PQEEVAAGQMASSSR;AMT(0.004)LS(0.996)PQEEVAAGQMASSSR;AMT(0.043)LS(0.957)PQEEVAAGQMASSSR;AMT(0.003)LS(0.997)PQEEVAAGQMASSSR;AMT(0.014)LS(0.943)PQEEVAAGQMAS(0.043)SSR;AMT(0.001)LS(0.999)PQEEVAAGQMASSSR 152.86 2.8378e-10 99153700.0 483522.0 376504.0 472334.0 406609.0 447468.0 426581.0 384889.0 336592.0 475225.0 355681.0 True False 476626.887612924 375632.22812033736 433500.52178196755 436512.38226786116 421148.8119959361 408337.1250388792 404816.66914365976 352231.2931095089 421700.1561588973 417159.9869348584 1.1425517847840754 0.9004512414537835 1.0391709065080128 1.0463908235188069 1.0095618592051125 0.9788501721826046 0.9704110696668372 0.8443554131295712 1.0108835203908182 1.0 18.67024125880679 -6.9795999012111265 2.035867309625113 0.9433676192010285 1.0231446630053995 0.18570295430134276 0.06951650072132372 0.5221938382911305 4.363589358207783 0.0292524942710466 0.023081581876680586 1.0480936717724909e-07 6.9795999012111265 0.079777043804371 AMTMPPVS(ph)PVGAEGPVVLR ddPTM_PC-9_AZD4547_30min_R2 2 AMTMPPVSPVGAEGPVVLR 19 0 A4QPE4;O15020 A4QPE4 SPTBN2 Spectrin beta chain, non-erythrocytic 2 1 AMT(0.369)MPPVS(0.631)PVGAEGPVVLR;AMT(0.003)MPPVS(0.997)PVGAEGPVVLR 72.891 0.0031558000000000003 28316000.0 51704.0 56984.0 69297.0 95957.0 70659.0 60874.0 54475.0 87591.0 64715.0 59331.0 True False 68144.79648999087 75402.96361714488 68378.07650214454 73835.59617087153 60849.217513120886 57067.539156856816 59323.16946794165 74055.82359094288 68135.70278170904 57253.83974895094 1.1902222940643816 1.3169940033327894 1.1942967808267817 1.2896182421061886 1.0627971465308723 0.9967460594274372 1.036143073164427 1.2934647512842106 1.1900634626511228 1.0 15.805084830855249 -6.261513164834211 24.99999994441387 1.1031998663040048 1.2489060559405876 0.39243753894328126 0.09196577836411765 8.155158573409299 2763048.658226914 0.03019356419644707 0.03644532855793113 5.476295003345477e-07 6.261513164834211 0.14570618963658277 AMTMPPVS(ph)PVGAEGPVVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AMTMPPVSPVGAEGPVVLR 19 0 A4QPE4;O15020 A4QPE4 SPTBN2 Spectrin beta chain, non-erythrocytic 2 1 AMT(0.41)MPPVS(0.59)PVGAEGPVVLR;AMT(0.01)MPPVS(0.99)PVGAEGPVVLR;AMT(0.001)MPPVS(0.999)PVGAEGPVVLR 75.564 0.0023899 20902600.0 40544.0 39524.0 42290.0 37459.0 54255.0 58027.0 66456.0 68486.0 55423.0 60379.0 True False 47407.29841949845 43447.681514983815 43298.3539857181 35360.29367371658 43624.122222776285 54983.961969304604 60160.806580225326 66688.31506691522 56233.45652498526 71325.23474009897 0.6646637559938674 0.6091488050940487 0.6070551908240103 0.4957613361184925 0.6116225538091479 0.7708907256970117 0.8434715539239998 0.9349890723797805 0.7884089933933421 1.0 16.122124969450653 -6.966739757196104 2.095576861391668 0.8899341569904464 0.5903956798310123 0.8241927581948552 0.06436978978688197 0.13060408458640974 1.1584021108461995 0.027659580238776547 0.02210497785854265 1.0795934545215331e-07 6.966739757196104 -0.29953847715943416 ANAS(ph)PQKPLDLK ddPTM_PC-9_Lapatinib_30min_R1 1 ANASPQKPLDLK 12 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 ANAS(1)PQKPLDLK 59.68 0.02978 169320000.0 1146200.0 936670.0 1041400.0 1126400.0 1043700.0 1062300.0 917860.0 823350.0 1037400.0 919530.0 True False 1129854.9778126625 934501.1981638325 955780.111920249 1209239.2135602478 982311.617993149 1016867.9053422482 965382.2996765289 861605.8467869518 920557.0876937041 1078469.5353032919 1.0476466333329664 0.866506811340784 0.8862374695187475 1.1212548653218843 0.9108385409485851 0.9428805098850384 0.8951410012755158 0.7989153319427306 0.8535772755368756 1.0 20.040553993029192 -7.188991494804959 2.213615755563774 0.8674800328218156 0.9638635626720755 0.15428889055215145 0.08527495010781234 0.5372911682810968 5.153802616985597 0.04018979320367544 0.02762118324858605 6.47155289471809e-08 7.188991494804959 0.09638352985025989 ANASNS(ph)PSSLR ddPTM_PC-9_AZD4547_30min_R2 1 ANASNSPSSLR 11 0 Q5T5X7 Q5T5X7 BEND3 BEN domain-containing protein 3 1 ANAS(0.208)NS(0.38)PS(0.38)S(0.033)LR 79.88600000000001 0.016781 5520700.0 21314.0 21295.0 24787.0 37011.0 29341.0 26940.0 18552.0 28961.0 20630.0 26445.0 True False 28091.408641259208 28178.192303578253 24458.30818446191 28478.68576424984 25267.508612526075 25255.43754124459 20203.09206001385 24485.742907573753 21720.459683020283 25519.168599231532 1.1007963888802057 1.1041971133976047 0.9584288802104011 1.1159723191415973 0.9901383939791426 0.9896653742083555 0.7916830041485846 0.9595039435693489 0.8511429202154477 1.0 14.639293707190465 -6.791844264026247 2.1211491809765235 0.8981855775606599 1.0623531839117306 0.5130679847732322 0.07036271848753178 0.24232164138179693 2.241293045813211 0.026790282347262235 0.024162571132185194 1.6149375620765875e-07 6.791844264026247 0.16416760635107075 ANASNS(ph)PSSLR ddPTM_PC-9_Lapatinib_30min_R1 1 ANASNSPSSLR 11 0 Q5T5X7 Q5T5X7 BEND3 BEN domain-containing protein 3 1 ANAS(0.196)NS(0.697)PS(0.099)S(0.008)LR 95.18299999999999 0.006324300000000001 3712100.0 53311.0 60123.0 49247.0 63934.0 71079.0 47688.0 76378.0 58321.0 68440.0 52530.0 True False 52550.77536395997 59983.78888744609 45198.101758917444 68635.91963757189 66898.27296669071 45648.49540615754 80332.47911957579 61030.80657127808 60731.566494849765 61609.74050817473 0.852962127912018 0.973608854585049 0.7336194144969708 1.1140433163886625 1.0858392263121814 0.7409298437168493 1.3038925088301065 0.9906032076726596 0.9857461822419388 1.0 15.910870838780069 -5.772253300509425 24.99768503846762 1.0326844811244296 0.865417982837317 0.24655564929164198 0.14226486534327942 306.2235362241833 707872.7380279202 0.039266588444410486 0.058897301745917396 1.6894552762381576e-06 5.772253300509425 -0.1672664982871126 ANASNSPS(ph)SLR ddPTM_PC-9_AZD4547_30min_R2 1 ANASNSPSSLR 11 0 Q5T5X7 Q5T5X7 BEND3 BEN domain-containing protein 3 1 ANAS(0.003)NS(0.123)PS(0.864)S(0.01)LR 103.13 0.0030305999999999996 4546200.0 16885.0 19831.0 12888.0 32112.0 30428.0 20233.0 18563.0 22693.0 18547.0 24376.0 True False 22254.078770182106 26240.982933658623 12717.096699130392 24709.074525454354 26203.597425511838 18967.827311507124 20215.071038704027 19186.31828326272 19527.356555549064 23522.60365947695 0.9460720884618666 1.1155645571185089 0.5406330388943504 1.0504396062252823 1.11397521315438 0.8063659782774614 0.8593891786532584 0.8156545321687977 0.8301528537501734 1.0 14.52176013694825 ANASNSPS(ph)SLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ANASNSPSSLR 11 0 Q5T5X7 Q5T5X7 BEND3 BEN domain-containing protein 3 1 ANAS(0.09)NS(0.206)PS(0.682)S(0.022)LR;ANAS(0.148)NS(0.242)PS(0.462)S(0.148)LR 74.78 0.022456 8447400.0 30591.0 34915.0 30304.0 28895.0 41279.0 43819.0 32795.0 41773.0 32121.0 25848.0 True False 35769.452100209106 38381.13045480367 31026.562288559984 27276.106828853954 33190.67627378089 41521.054501059145 29688.42018476117 40676.50301215205 32590.708858038237 30534.037787344576 1.1714615783646685 1.2569949222605428 1.016130342951876 0.8933016661215722 1.087005803324754 1.3598284901012454 0.9723057393040272 1.3321691449864914 1.0673566688106375 1.0 14.898130762104161 -6.562534309073609 24.999931108051328 1.1636826901947304 1.0791928625384448 0.034506283152347716 0.14772143709286678 470.7633299753923 296778.72679002734 0.04893244393021513 0.048932508609867365 2.738203308859118e-07 6.562534309073609 -0.08448982765628554 ANASNSPS(ph)SLR ddPTM_PC-9_Lapatinib_30min_R1 2 ANASNSPSSLR 11 0 Q5T5X7 Q5T5X7 BEND3 BEN domain-containing protein 3 1 ANAS(0.023)NS(0.119)PS(0.782)S(0.076)LR;ANAS(0.025)NS(0.125)PS(0.837)S(0.013)LR 98.0 0.0051576999999999994 8524700.0 46484.0 40519.0 52995.0 45361.0 42367.0 43309.0 41918.0 47744.0 54063.0 31723.0 True False 45821.12963587843 40425.18074497992 48637.95566661579 48696.999259860095 39875.05635672683 41456.77502820997 44088.30893365079 49962.36053804114 47973.85563137144 37206.27828175953 1.2315429479100133 1.0865150348778225 1.3072513003930486 1.3088382259327969 1.0717292402845806 1.114241384592725 1.1849696064673363 1.3428475742637047 1.2894021613253037 1.0 15.183258465444899 -12.65473876895565 10.80034795981921 1.203758864674679 1.2007890220816908 0.0 0.11391203715473877 0.0 0.0 0.0 0.026326751999343735 2.214426301360658e-13 12.65473876895565 -0.00296984259298827 ANASNSPSS(ph)LR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ANASNSPSSLR 11 0 Q5T5X7 Q5T5X7 BEND3 BEN domain-containing protein 3 1 ANAS(0.031)NS(0.053)PS(0.273)S(0.643)LR 66.00399999999999 0.043281 4606800.0 18184.0 18230.0 24269.0 21363.0 22722.0 22764.0 21255.0 22208.0 24358.0 14430.0 True False 21262.19204962905 20039.753922127184 24847.665000695026 20166.100369780474 18269.787211241786 21570.215766268306 19241.572527126045 21625.063531321015 24714.189669191346 17046.044772182842 1.247338742435223 1.1756248554990143 1.4576792055153767 1.1830369237730267 1.0717904038980322 1.265408841438008 1.1287998350518267 1.2686264655722714 1.4498489238701298 1.0 14.057149406217357 -11.760233423826861 2.4795347473173925 0.05377578880418537 1.2439832068105003 0.28455738779034845 0.11850281511378162 6708387.208983526 1995187.4631418039 36895448.22909866 0.030632967161424676 1.7368670496115902e-12 11.760233423826861 1.190207418006315 ANDDIIVNWVNR ddPTM_PC-9_AZD4547_30min_R2 1 ANDDIIVNWVNR 12 0 A0A0A0MSQ0;P13797-3;P13797-2;P13797 A0A0A0MSQ0 PLS3 Plastin-3 0 167.11 0.0041618 4211900.0 7432.3 7122.8 12044.0 10445.0 8826.2 8916.1 5751.0 8783.5 10140.0 8973.5 False True 9795.616798556384 9425.105806054331 11884.288690590192 8037.066623641346 7600.834481301855 8358.57485751636 6262.827858836764 7426.211899750493 10675.979698779718 8659.340496320829 1.1312197277284957 1.0884322899716046 1.3724242274154224 0.9281384219798409 0.8777613589084861 0.9652669116161608 0.7232453627961284 0.8575955527913164 1.232886003653017 1.0 13.080041436759743 -5.797971926871144 21.786361343295155 0.9241053535118184 1.1864655884817898 0.40853158346928065 0.14034790538379974 40.43812929727451 24115.01600098725 0.039816597439431084 0.059063366975083645 1.5923116519726687e-06 5.797971926871144 0.2623602349699714 ANDDIIVNWVNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ANDDIIVNWVNR 12 0 A0A0A0MSQ0;P13797-3;P13797-2;P13797 A0A0A0MSQ0 PLS3 Plastin-3 0 134.98 0.00042202 0.0 8569.6 12932.0 14755.0 11803.0 13627.0 9407.6 13220.0 11985.0 10308.0 10018.0 False True 10020.26402268483 14215.803495389406 15106.815158649119 11141.716175842292 10956.887172238003 8914.248894866701 11967.705895488416 11670.406449157163 10458.73499917991 11834.184097555628 0.8467219995972967 1.2012491421631428 1.2765404893244359 0.9414857909928606 0.9258675614570816 0.7532626517706409 1.0112827210420334 0.9861606303359525 0.8837732211162898 1.0 13.530672623096699 -5.903226971033271 10.08809765932616 0.9226966092082743 1.1172401846586275 0.3047462783453744 0.12397870337723382 0.38300083745413216 36.80769199026279 0.03530820502518134 0.052430262846448736 1.2496057904091302e-06 5.903226971033271 0.19454357545035317 ANDDIIVNWVNR ddPTM_PC-9_Lapatinib_30min_R1 3 ANDDIIVNWVNR 12 0 A0A0A0MSQ0;P13797-3;P13797-2;P13797 A0A0A0MSQ0 PLS3 Plastin-3 0 ;; 208.56 2.1976999999999996e-07 16045200.0 52567.0 61003.0 66593.0 56685.0 64951.0 70097.0 55723.0 61949.0 61535.0 56864.0 False True 51817.38494039284 60861.75130151312 61117.98059641369 60853.80399561672 61130.70987857917 67099.114714088 58608.06428526703 64827.376695943225 54604.28030772323 66692.86663348276 0.7769554310082426 0.9125676308979923 0.9164095604451012 0.9124484681404507 0.9166004246680387 1.0060913273204737 0.8787756059033036 0.9720286436660233 0.8187424392447614 1.0 16.02524484076667 -4.751086358478538 3.845764347855418 0.9262484419912744 0.7569708966209648 0.4177057403462836 0.053016808114891574 0.26832061246845995 6.908868597264681 0.012358121704520728 0.13437909200046916 1.7738367223858708e-05 4.751086358478538 -0.1692775453703096 ANDT(ph)SEEMRHR ddPTM_PC-9_AZD4547_30min_R2 1 ANDTSEEMRHR 11 1 H0Y7P0;A0A0A0MSV2;Q7Z2W7-4;Q7Z2W7 H0Y7P0 TRPM8 Transient receptor potential cation channel subfamily M member 8 1 ANDT(0.601)S(0.399)EEMRHR 58.32 0.045276 2275800.0 5567.4 4128.9 5634.8 9684.5 6489.6 7487.5 5506.9 4357.9 6717.1 7825.1 True False 7337.717390886102 5463.486179959811 5560.078870287082 7451.888149033469 5588.631058649982 7019.305441353708 5997.00343172112 3684.4866895796326 7072.1521927685635 7551.1456307750705 0.971735647764608 0.7235307656752242 0.7363225584773129 0.9868553082412989 0.7401037315282648 0.9295682780565347 0.7941845813806099 0.4879374428382527 0.9365667858325569 1.0 12.882479825848629 -7.519676835245855 24.99962664932406 0.7555635206954168 0.8406214284415398 0.0 0.15662509540190936 430.18067065156157 3358814.6121192654 0.06873386321480571 0.040705342957523365 3.022199746090162e-08 7.519676835245855 0.08505790774612298 ANDTS(ph)EEMRHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ANDTSEEMRHR 11 1 H0Y7P0;A0A0A0MSV2;Q7Z2W7-4;Q7Z2W7 H0Y7P0 TRPM8 Transient receptor potential cation channel subfamily M member 8 1 ANDT(0.102)S(0.898)EEMRHR 57.347 0.032327 1732700.0 7759.2 5760.2 6860.4 8082.4 7021.8 7187.5 6448.4 8404.6 6526.3 8004.0 True False 9072.679308814437 6332.034588164399 7023.977954211881 7629.569331494343 5645.92869641306 6810.57484712939 5837.560869626889 8183.98815540979 6621.734790953423 9455.061840370861 0.9595579026333025 0.6696978502169197 0.7428801707272996 0.8069296066280497 0.5971329211519579 0.7203099209832619 0.6174006017286842 0.8655668565239955 0.7003375443490166 1.0 13.206871178744539 -10.492303531549995 4.1302245834003894 1.000013621937033 0.7370399433000975 0.34925398922374207 0.1053572718034726 44727462.16472637 90699842.56957759 9316.254703335851 0.02521687232583835 3.218818349558367e-11 10.492303531549995 -0.26297367863693555 ANDTS(ph)EEMRHR ddPTM_PC-9_Lapatinib_30min_R1 1 ANDTSEEMRHR 11 1 H0Y7P0;A0A0A0MSV2;Q7Z2W7-4;Q7Z2W7 H0Y7P0 TRPM8 Transient receptor potential cation channel subfamily M member 8 1 ANDT(0.179)S(0.821)EEMRHR 61.815 0.024322999999999997 2304500.0 5278.1 3802.6 3685.9 4460.8 4086.1 5574.6 3148.3 4945.3 4249.0 4009.9 True False 5202.833326115002 3793.7953133310452 3382.859529985454 4788.862112792574 3845.763631581691 5336.1873530273 3311.303569249792 5175.076691705237 3770.432876046414 4703.005872144106 1.1062782968082971 0.8066745856733215 0.7192973221705131 1.0182556099189657 0.8177246076514896 1.1346333596208173 0.7040823803479889 1.1003764044517157 0.8017070313219636 1.0 12.19936741819923 ANEAGGQVGPEAPRPPET(ph)SPEMR ddPTM_PC-9_AZD4547_30min_R2 1 ANEAGGQVGPEAPRPPETSPEMR 23 1 Q8N3D4;E9PIH6 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 ANEAGGQVGPEAPRPPET(0.5)S(0.5)PEMR 56.403999999999996 0.0062053 8567900.0 2968.6 8715.6 11294.0 18406.0 10656.0 10883.0 6100.8 13995.0 9225.5 11346.0 True False 3912.5530492841326 11532.747257152683 11144.234180631498 14162.78106986526 9176.598335948933 10202.484289582959 6643.759381184372 11832.394323106757 9713.141095768475 10948.779993453623 0.3573505953744147 1.0533362862390347 1.0178516864248564 1.2935487861052388 0.838138892318204 0.9318375468027597 0.6068036242537285 1.0807043643384426 0.887143691039189 1.0 13.418482500932683 -4.7563870483368715 24.995679042890284 0.9655306261474184 0.3573496546377948 0.5407700370605718 0.16872756329172206 129.06920489179538 638479.0564280312 0.04342367836391164 0.3533000886656566 1.752318119274436e-05 4.7563870483368715 -0.6081809715096236 ANEAGGQVGPEAPRPPET(ph)SPEMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ANEAGGQVGPEAPRPPETSPEMR 23 1 Q8N3D4;E9PIH6 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 ANEAGGQVGPEAPRPPET(0.5)S(0.5)PEMR;ANEAGGQVGPEAPRPPET(0.5)S(0.5)PEMR 62.303000000000004 0.0022806999999999997 75445000.0 62814.0 65372.0 73535.0 82611.0 100732.0 70454.0 73348.0 70370.0 71601.0 64116.0 True False 73447.16956694888 71861.70013150296 75288.35328304043 77982.57349847554 80994.28771071235 66759.26821282148 66399.9464464662 68522.86206317805 72648.02916921629 75739.7232580234 0.9697311583346503 0.9487980288321212 0.9940405119590248 1.029612601472168 1.0693765995789049 0.8814300520400887 0.8766858867474433 0.9047149780273215 0.9591800186769286 1.0 16.20876252938273 -6.776634894820235 24.9999874567322 0.9154646020608598 1.000396003954332 0.4116661276874116 0.045923842950721 236.92241308664694 389787.3649440694 0.016983153850670688 0.015034469406982743 1.6724960670568625e-07 6.776634894820235 0.08493140189347226 ANEAGGQVGPEAPRPPET(ph)SPEMR ddPTM_PC-9_Lapatinib_30min_R1 4 ANEAGGQVGPEAPRPPETSPEMR 23 1 Q8N3D4;E9PIH6 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 ANEAGGQVGPEAPRPPET(0.5)S(0.5)PEMR;ANEAGGQVGPEAPRPPET(0.5)S(0.5)PEMR;ANEAGGQVGPEAPRPPET(0.5)S(0.5)PEMR;ANEAGGQVGPEAPRPPET(0.5)S(0.5)PEMR 56.684 0.0054123999999999995 95144000.0 111388.0 112711.0 113111.0 88348.8 100635.0 98719.0 83142.9 89920.0 110148.0 74735.1 True False 109799.5866939425 112450.02460444316 103811.4502010864 94846.26547495715 94715.84715602243 94497.0184952287 87447.63254066583 94098.01146909897 97741.97233013879 87652.96245673869 1.2526625868251096 1.2829004457201671 1.1843461680182545 1.0820657147985013 1.0805778207755343 1.078081286093073 0.9976574674680938 1.0735291635527007 1.1151017557265055 1.0 16.41951523093838 -5.618030365107258 1.996043584499664 1.0591037450964975 1.271509276896811 0.8550603154325895 0.03495405106576042 0.11632257657166388 0.92815946228161 0.010482845547333145 0.024229568301153463 2.409736938222801e-06 5.618030365107258 0.21240553180031352 ANEAGGQVGPEAPRPPETS(ph)PEMR ddPTM_PC-9_Lapatinib_30min_R1 3 ANEAGGQVGPEAPRPPETSPEMR 23 1 Q8N3D4;E9PIH6 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 ANEAGGQVGPEAPRPPET(0.358)S(0.642)PEMR;ANEAGGQVGPEAPRPPET(0.292)S(0.708)PEMR;ANEAGGQVGPEAPRPPET(0.284)S(0.716)PEMR 80.832 7.8096e-05 42904000.0 30477.3 29131.5 36091.5 27179.1 28633.0 27781.4 20679.2 21178.3 30717.8 19712.9 True False 30042.688113147684 29064.047801584016 33124.1961872189 29177.941680819706 26948.863234643904 26593.254283606475 21749.867791897294 22162.321133185258 27258.037891225806 23120.248499211837 1.2994102599793351 1.2570819817345302 1.4326920486320938 1.2620081346363718 1.165595743296729 1.1502148986207061 0.9407281151255248 0.9585676007738743 1.178968205819891 1.0 14.496869283731204 -6.60503511270912 1.4905961724128312 1.021236961282319 1.3220639889201558 0.7261456031709301 0.07904661656968028 0.20733493355736074 0.9520098964667155 0.0338291893439269 0.03493524819571492 2.4829323520980873e-07 6.60503511270912 0.30082702763783686 ANES(ph)SPKPVGPPPER ddPTM_PC-9_AZD4547_30min_R2 1 ANESSPKPVGPPPER 15 1 A6PVM9;Q9BQI0-3;Q9BQI0;Q9BQI0-2 A6PVM9 AIF1L Allograft inflammatory factor 1-like 1 ANES(0.508)S(0.492)PKPVGPPPER 52.731 0.03974 42085000.0 30150.0 36310.0 31241.0 51110.0 39881.0 38909.0 32072.0 45322.0 38479.0 37772.0 True False 39737.072841041794 48046.49741924985 30826.72392749321 39327.37914162844 34344.21154616925 36476.014079149405 34926.34586830336 38318.52629595171 40512.921383564564 36449.61377690203 1.0901918764972762 1.3181620445508457 0.8457352694098499 1.0789518753844805 0.9422380098834693 1.0007242958021165 0.9582089424068477 1.051273863434844 1.111477384411613 1.0 15.153615907267637 -5.254515133162213 24.999777365773298 0.9999009246744271 1.2041769526137218 0.4703245446552625 0.08726610993121371 439.1682514794999 1585593.1287826435 0.021071504527152413 0.05319710822114084 5.565252415792279e-06 5.254515133162213 0.20427602793929467 ANES(ph)SPKPVGPPPER ddPTM_PC-9_Lapatinib_30min_R1 1 ANESSPKPVGPPPER 15 1 A6PVM9;Q9BQI0-3;Q9BQI0;Q9BQI0-2 A6PVM9 AIF1L Allograft inflammatory factor 1-like 1 ANES(0.844)S(0.156)PKPVGPPPER 68.262 0.013283000000000001 42603000.0 57050.0 47238.0 43349.0 48139.0 47531.0 45511.0 39813.0 49611.0 45194.0 33095.0 True False 56236.456538311315 47128.62331329407 39785.01255197903 51679.302646996446 44735.32002954144 43564.60062132269 41874.32233349489 51916.108173859764 40103.77580608178 38815.426653684466 1.448817168494867 1.2141724921325963 1.0249793956136388 1.3314114284530454 1.1525139328925822 1.1223527441810925 1.0788061846415404 1.3375122380351767 1.0331916782441195 1.0 15.244342525093842 -4.797027941363994 3.7964769192698977 1.150582815166369 1.4739372125874854 0.40771018169312645 0.11236018102131003 0.2354348095541839 6.01209301702058 0.02670421238738612 0.20680156400645394 1.595776475875256e-05 4.797027941363994 0.3233543974211164 ANESS(ph)PKPVGPPPER ddPTM_PC-9_AZD4547_30min_R2 1 ANESSPKPVGPPPER 15 1 A6PVM9;Q9BQI0-3;Q9BQI0;Q9BQI0-2 A6PVM9 AIF1L Allograft inflammatory factor 1-like 1 ANES(0.018)S(0.982)PKPVGPPPER 111.34 0.0020862 6811400.0 17411.0 19172.0 20569.0 20056.0 21662.0 20134.0 16444.0 19171.0 16280.0 19747.0 True False 22947.335828702446 25368.97407110597 20296.24162045416 15432.399062111128 18654.605213337636 18875.01779715733 17907.484143750957 16208.562455754176 17140.527563721276 19055.663540519003 1.2042265429334638 1.3313088792296666 1.0651028539256717 0.8098589182841338 0.9789533265882567 0.9905201021744765 0.9397460290833424 0.850590294129045 0.8994978069000076 1.0 14.21793222490494 -5.474972789054095 4.3246968313993275 0.9235961051681253 1.2617057237738576 0.8174659693682502 0.06450703414976361 0.08092388915420635 3.2153665913507883 0.017443058764721176 0.036628843605300845 3.3498642724856945e-06 5.474972789054095 0.3381096186057323 ANGLPAGPEPASEPGS(ph)PYPEGPR ddPTM_PC-9_AZD4547_30min_R2 1 ANGLPAGPEPASEPGSPYPEGPR 23 0 Q5VTI5;A0A1B0GUN5;Q9Y2H5;A0A5F9ZH45 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 ANGLPAGPEPAS(0.35)EPGS(0.649)PYPEGPR 130.17 7.832800000000001e-07 5797700.0 9707.7 12773.0 25032.0 31473.0 22920.0 21693.0 20516.0 34084.0 27443.0 19959.0 True False 12794.546667296241 16901.622460371214 24700.059324381753 24217.386103002762 19737.953627998282 20336.533280705968 22341.884255241686 28817.100972402335 28893.58095400512 19260.24148504678 0.6642983514630199 0.8775394884582967 1.2824376757455678 1.2573770750384723 1.0248030193869786 1.0558815317292256 1.1600002145657118 1.4961962442046892 1.5001671176572449 1.0 14.233338171365057 -5.077114856303834 3.096972866716584 1.2259219982888665 0.6824211909085791 0.5508128210537682 0.1676239108379445 0.2098939045567423 3.7382770028389642 0.04825522840234958 0.1925351774662848 8.37307813048676e-06 5.077114856303834 -0.5435008073802874 ANGLPAGPEPASEPGS(ph)PYPEGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ANGLPAGPEPASEPGSPYPEGPR 23 0 Q5VTI5;A0A1B0GUN5;Q9Y2H5;A0A5F9ZH45 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 ANGLPAGPEPAS(0.02)EPGS(0.98)PYPEGPR;ANGLPAGPEPAS(0.031)EPGS(0.969)PYPEGPR 185.3 1.0966e-52 4421800.0 18062.4 22439.7 27913.0 32107.0 37897.0 30824.0 34798.0 35018.0 32954.0 25622.0 True False 21120.00757133851 24667.365117189125 28578.55178064198 30308.14888229847 30471.354895890752 29207.53517744923 31501.681524296968 34098.81460463793 33435.88990715704 30267.065776359617 0.6977884056350944 0.8149903033037252 0.9442128282868943 1.0013573534429274 1.006749551510563 0.9649939440202379 1.0407907313203006 1.1265979615133734 1.104695451954661 1.0 14.885461200235843 -3.992202224864006 0.5254056139811121 1.0659840088606665 3.3682222518400795e-14 0.8819430959029735 0.04204329051634806 3.0799761492416757 0.3487774049050443 0.025588022371178357 2.4109867264246487 0.00010181172016123297 3.992202224864006 -1.0659840088606327 ANGPHLYS(ph)SPTDSTDPR ddPTM_PC-9_AZD4547_30min_R2 1 ANGPHLYSSPTDSTDPR 17 0 Q96QT6;C9J9G2;Q96QT6-4;Q96QT6-2;Q96QT6-5;Q96QT6-3;K7EPF7 Q96QT6 PHF12 PHD finger protein 12 1 ANGPHLY(0.001)S(0.498)S(0.498)PT(0.002)DSTDPR 102.79 0.00052624 4425300.0 10407.0 10722.0 10595.0 19441.0 15467.0 15529.0 13274.0 16939.0 9963.1 13704.0 True False 13716.209520952629 14187.676819862216 10454.503377349976 14959.177810455847 13319.67402985382 14557.969175129445 14455.360284854658 14321.466769496636 10489.729125928223 13224.227131172971 1.0372031109946627 1.0728548957252966 0.7905568524837244 1.1311948639473337 1.007217578595263 1.100855954055152 1.093096794350997 1.0829719292810076 0.7932205808232967 1.0 13.690895788345765 -8.246109614895987 24.932163919384184 0.8966102705545432 1.0381210977311206 0.24165281273051942 0.10122329374471876 967.3413725710238 1573280.2491202657 0.06793045515450823 0.025463098774272278 5.6740137657386285e-09 8.246109614895987 0.14151082717657737 ANGPHLYS(ph)SPTDSTDPR ddPTM_PC-9_Lapatinib_30min_R1 1 ANGPHLYSSPTDSTDPR 17 0 Q96QT6;C9J9G2;Q96QT6-4;Q96QT6-2;Q96QT6-5;Q96QT6-3;K7EPF7 Q96QT6 PHF12 PHD finger protein 12 1 ANGPHLYS(0.633)S(0.363)PT(0.001)DS(0.001)T(0.001)DPR 121.77 3.8141999999999995e-05 3386600.0 14130.0 12212.0 14981.0 7507.6 14503.0 11384.0 11591.0 11639.0 11635.0 8760.8 True False 13928.503608875355 12183.723864303038 13749.32000833232 8059.733948619421 13649.962053995061 10897.132857400135 12191.125264801429 12179.790430258488 10324.543778018357 10275.092606967783 1.3555599099350315 1.1857531927294716 1.3381212738665327 0.7843952611340871 1.3284514871173716 1.0605386514969735 1.1864735171860485 1.1853703802142947 1.0048127226626689 1.0 13.326863776182549 ANGPHLYSS(ph)PTDSTDPR ddPTM_PC-9_Lapatinib_30min_R1 1 ANGPHLYSSPTDSTDPR 17 0 Q96QT6;C9J9G2;Q96QT6-4;Q96QT6-2;Q96QT6-5;Q96QT6-3;K7EPF7 Q96QT6 PHF12 PHD finger protein 12 1 ANGPHLYS(0.008)S(0.991)PT(0.001)DSTDPR 144.4 5.0749e-09 0.0 15702.0 13585.0 16015.0 11648.0 14318.0 11570.0 13174.0 10107.0 15894.0 12015.0 True False 15478.086600605866 13553.544767159918 14698.30851968774 12504.63277658893 13475.843390271073 11075.178070987316 13856.08525912293 10576.60811741752 14103.850348760096 14091.77674101884 1.0983772227636637 0.9618052440263108 1.0430415404541136 0.8873709118730219 0.9562912922857423 0.7859319853364762 0.9832745376095939 0.7505517800768696 1.0008567839217968 1.0 13.782565902755222 -5.762673731945331 24.999589524993915 0.8987033840523544 1.0271477453959268 0.29754796240671844 0.08692271333313853 36.64251019675027 742156.5026414677 0.022303571374234697 0.035258042706806554 1.7271349320403052e-06 5.762673731945331 0.1284443613435724 ANGQENGHVKS(ph)NGDLSPK ddPTM_PC-9_AZD4547_30min_R2 4 ANGQENGHVKSNGDLSPK 18 1 P49006 P49006 MARCKSL1 MARCKS-related protein 1 ANGQENGHVKS(0.874)NGDLS(0.126)PK;ANGQENGHVKS(0.735)NGDLS(0.265)PK;ANGQENGHVKS(0.843)NGDLS(0.157)PK;ANGQENGHVKS(0.954)NGDLS(0.046)PK 67.56 0.0060648 35315400.0 40948.9 45514.9 80489.0 126182.0 132526.0 110599.0 99970.0 94871.0 94877.0 110919.0 True False 53969.79840996807 60226.70133261951 79421.66326942176 97092.68939246642 114127.05246527464 103683.22704618088 108867.13633244859 80210.86686870045 99892.0045247655 107035.7595711159 0.504222127504125 0.5626783196003214 0.7420105541144221 0.9071051560853065 1.0662516239672892 0.9686783880605103 1.017109952493175 0.7493838245283564 0.9332582393494019 1.0 16.707733341503207 -5.484079894404211 1.9504393608200472 0.9498970648809827 0.5137365453149093 0.818242179514054 0.07920190190165056 0.1521475642386258 1.1160270027063601 0.02507202400688873 0.07005816348463527 3.280349410522712e-06 5.484079894404211 -0.4361605195660734 ANGQENGHVKS(ph)NGDLSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ANGQENGHVKSNGDLSPK 18 1 P49006 P49006 MARCKSL1 MARCKS-related protein 1 ANGQENGHVKS(0.779)NGDLS(0.221)PK 52.06100000000001 0.027226999999999998 7327500.0 8781.3 4997.3 8731.7 20275.0 24323.0 23469.0 22999.0 22978.0 20153.0 20730.0 True False 10267.800651419238 5493.398917994855 8939.896843156659 19139.057482436896 19557.082754116454 22238.244325186737 20820.368221659446 22374.851847203463 20447.69949926978 24488.18490141028 0.41929610923625105 0.22432854619937506 0.3650698032193398 0.781562927570621 0.7986334157820801 0.9081213824020918 0.8502209659671589 0.9136998898564708 0.8350026586940787 1.0 14.579798222835574 -5.794145892407895 3.08329822309472 0.8749620629351216 0.30972683848215693 0.9296920026545547 0.06773030316110987 0.05514591855463192 1.073034912300276 0.018967179542675846 0.032210651928392786 1.606401524406696e-06 5.794145892407895 -0.5652352244529646 down ANGQENGHVKS(ph)NGDLSPK ddPTM_PC-9_Lapatinib_30min_R1 2 ANGQENGHVKSNGDLSPK 18 1 P49006 P49006 MARCKSL1 MARCKS-related protein 1 ANGQENGHVKS(0.5)NGDLS(0.5)PK;ANGQENGHVKS(0.964)NGDLS(0.036)PK 65.915 0.0068316 16242300.0 69261.0 30145.0 31952.0 24398.0 26899.0 31581.0 23902.0 23956.0 39340.0 23113.3 True False 68273.32543908806 30075.201104603293 29325.029898286775 26192.310309342098 25316.853705468737 30230.35424890669 25139.528606615804 25069.083215677652 34909.11493143464 27108.40310846366 2.518529961573874 1.109442005280398 1.0817689917386188 0.966206316341978 0.9339116584688985 1.1151654388475694 0.9273703252098556 0.9247716700749038 1.2877599167962601 1.0 14.726452509495436 -4.759951286978545 5.0292898190592155 1.024817936773566 2.6147407296660403 0.9461989966731493 0.10602227865543933 0.03461207272789264 2.3242356247820184 0.025905587087144768 0.19522768548020977 1.7379957616356526e-05 4.759951286978545 1.5899227928924744 up ANGQENGHVKSNGDLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 ANGQENGHVKSNGDLSPK 18 1 P49006 P49006 MARCKSL1 MARCKS-related protein 1 ANGQENGHVKS(0.008)NGDLS(0.992)PK 87.79299999999999 0.00075797 13962000.0 29608.0 11683.0 10441.0 14934.0 12668.0 15042.0 10275.0 10370.0 17766.0 9917.1 True False 29185.784490557777 11655.948731301378 9582.58128342553 16032.29617836358 11922.893146246259 14398.688724614616 10806.989224038873 10851.82805754622 15765.005995726178 11631.257521294881 2.509254432474176 1.0021228323731368 0.823864596401673 1.3783802954247324 1.025073438913844 1.2379305245587617 0.9291333464376563 0.9329883753049353 1.3553999614283405 1.0 13.505719462745757 -4.759686721170252 24.99999737995893 1.074439009783243 2.509256221195172 0.8543379324218782 0.17752925122375252 15.557105163412512 221842.9382105107 0.04292335793273062 0.26799451291044357 1.7390548456377212e-05 4.759686721170252 1.434817211411929 ANGSQPNSGS(ph)PQPAP ddPTM_PC-9_AZD4547_30min_R2 4 ANGSQPNSGSPQPAP 15 0 J3KR72;P49848-4;P49848-2;P49848;P49848-3 J3KR72 TAF6 Transcription initiation factor TFIID subunit 6 1 ANGSQPNS(0.005)GS(0.995)PQPAP;ANGSQPNS(0.004)GS(0.996)PQPAP;ANGSQPNS(0.006)GS(0.994)PQPAP;ANGSQPNS(0.011)GS(0.989)PQPAP 118.16 0.0017525 0.0 36875.5 37175.7 54144.9 70030.0 58134.0 54932.0 48918.4 59690.0 41519.3 48058.4 True False 48601.14194195147 49192.01801456366 53426.90324835085 53885.665452714464 50063.09756588362 51497.093356185855 53272.0428325022 50466.28203974576 43713.925434669116 46375.890043838495 1.0479829475188396 1.060723966010423 1.1520404934082586 1.1619327500081849 1.0795069920719507 1.1104281407323149 1.1487012493376378 1.0882008300442465 0.9426002475283373 1.0 15.50108734968203 -8.179644715326706 5.183297550692989 0.9721225533469434 1.1098709070086603 0.6611157627308868 0.03873957591287738 0.12699142289472581 5.729945392115974 0.029477752218164767 0.010489266272819356 6.6123416474864815e-09 8.179644715326706 0.1377483536617169 ANGSQPNSGS(ph)PQPAP ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ANGSQPNSGSPQPAP 15 0 J3KR72;P49848-4;P49848-2;P49848;P49848-3 J3KR72 TAF6 Transcription initiation factor TFIID subunit 6 1 ANGSQPNS(0.016)GS(0.984)PQPAP;ANGSQPNS(0.035)GS(0.965)PQPAP;ANGSQPNS(0.226)GS(0.773)PQPAP 103.14 0.0070161 0.0 25925.300000000003 27792.5 28822.2 30155.4 35730.6 29218.4 31409.9 29667.0 31902.5 21482.1 True False 30313.94124198458 30551.555725766324 29509.430556802195 28465.890703125875 28729.445424258243 27686.135667946488 28434.526884016745 28888.27268478478 32369.013708899627 25376.634677789978 1.1945611239190754 1.2039246383014497 1.162858311651123 1.1217362374704343 1.1321219613648257 1.0910089544764507 1.1205003045144943 1.1383807605532597 1.275543984452339 1.0 14.631213138421892 -5.497192760468963 3.078039125585309 1.1300745950484705 1.198937593579486 0.1775906516474266 0.06320253018813839 0.46115548311845056 8.784786472522006 0.017123898884151324 0.03757074681934338 3.182784537589061e-06 5.497192760468963 0.0688629985310154 ANGSQPNSGS(ph)PQPAP ddPTM_PC-9_Lapatinib_30min_R1 3 ANGSQPNSGSPQPAP 15 0 J3KR72;P49848-4;P49848-2;P49848;P49848-3 J3KR72 TAF6 Transcription initiation factor TFIID subunit 6 1 ANGSQPNS(0.004)GS(0.996)PQPAP;ANGS(0.001)QPNS(0.111)GS(0.888)PQPAP;ANGSQPNS(0.017)GS(0.983)PQPAP 128.73 1.7143e-05 7583800.0 56268.0 41036.0 40821.0 34653.3 40919.0 43736.0 33182.0 32572.6 46565.0 29836.0 True False 55465.608001712586 40940.98366324432 37464.85495361683 37201.81928202002 38512.224869849255 41865.51323359559 34900.00159922708 34086.04190812247 41320.35934881176 34993.112846028984 1.5850435554494209 1.1699726127077117 1.070635102354672 1.0631183183305077 1.1005658467511734 1.1963929421713762 0.9973391550728397 0.9740785867808428 1.1808140513427 1.0 15.094783386161437 -4.737694959490864 2.698775511354289 1.0748255133787474 1.7203952772576516 0.8277942390430486 0.06983241790106282 0.21482513735455097 1.884195698592523 0.018175676569152623 0.3308095336228791 1.8293846913766787e-05 4.737694959490864 0.6455697638789042 ANHLGDSGGT(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 3 ANHLGDSGGTPVK 13 0 C9JIE2;Q86TI0-2;Q86TI0;H7C380;H7C0Z7;H0Y8P0 C9JIE2 TBC1D1 TBC1 domain family member 1 1 ANHLGDSGGT(1)PVK;ANHLGDSGGT(1)PVK;ANHLGDSGGT(1)PVK 122.08 0.0004907000000000001 13863100.0 101267.0 118386.0 152183.0 202140.0 186819.0 177114.0 148675.0 164767.0 148105.0 169215.0 True False 133467.79951554825 156651.95933559115 150164.95398539424 155539.7460318681 160882.40658067263 166039.0335812916 161906.78697836126 139306.04611899503 155933.52793765004 163290.83435503714 0.8173624688900433 0.9593432476129595 0.9196165515260717 0.9525320061362652 0.9852506860910027 1.0168300887009931 0.9915240351233273 0.8531161388771346 0.9549435432402141 1.0 17.317084287984045 -4.053200303242555 1.6218753432546773 0.9591232479014972 2.2153189929238746e-11 0.4684506278358619 0.04477061046184561 9.60413542318224 4.1893198787728645 0.013133240200513194 25.82081985309105 8.847074751305869e-05 4.053200303242555 -0.959123247879344 ANHLGDSGGT(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ANHLGDSGGTPVK 13 0 C9JIE2;Q86TI0-2;Q86TI0;H7C380;H7C0Z7;H0Y8P0 C9JIE2 TBC1D1 TBC1 domain family member 1 1 ANHLGDSGGT(1)PVK;ANHLGDSGGT(1)PVK;ANHLGDSGGT(1)PVK;ANHLGDSGGT(1)PVK 149.97 0.00012239 17175200.0 72595.0 89467.0 105791.0 120624.0 127010.0 114442.0 122086.0 110384.0 102268.0 79833.0 True False 84883.89968339312 98348.69249319541 108313.45865460158 113865.82834828454 102123.30224891374 108440.46005637303 110521.13025390323 107486.53696151583 103763.47602795207 94306.09094231974 0.9000892607807326 1.0428668128482628 1.1485308909776477 1.207406936397439 1.0828919026171409 1.1498775844997993 1.1719405305591668 1.1397624043950418 1.1002839264265203 1.0 16.525063332724457 -4.874257249577001 2.502746439012937 1.1336605481437556 0.8736196802056587 0.6161268974276984 0.054133798675062295 0.2486498406597293 2.330163320373223 0.013505162016700002 0.12871959730295524 1.3358040332760867e-05 4.874257249577001 -0.2600408679380969 ANHLGDSGGT(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 3 ANHLGDSGGTPVK 13 0 C9JIE2;Q86TI0-2;Q86TI0;H7C380;H7C0Z7;H0Y8P0 C9JIE2 TBC1D1 TBC1 domain family member 1 1 ANHLGDSGGT(1)PVK;ANHLGDSGGT(1)PVK;ANHLGDSGGT(1)PVK 140.46 0.00015288 13871300.0 80271.0 69014.0 84862.0 71151.0 90857.0 81317.0 72325.0 82634.0 106251.0 73247.0 True False 79126.32082010132 68854.20232320762 77884.97393679303 76383.68189277823 85512.96989173481 77839.26146918543 76069.63461105719 86473.47731024837 94283.89350736822 85907.64635450732 0.9210626082523304 0.8014909643673999 0.9066128248397372 0.889137173861947 0.9954058051928948 0.9060807130947713 0.8854815355684115 1.0065865028289342 1.097502929114079 1.0 16.390498926126014 -7.88058466976634 4.133615904913381 1.049903124060703 0.9006223318528814 0.6102291295339219 0.049659591374704035 0.14786300941970681 4.489366346049038 0.030496258366026808 0.013739652714880595 1.3164832269973642e-08 7.88058466976634 -0.14928079220782164 ANLACS(ph)PLGGGEPSPGAGEPSK ddPTM_PC-9_AZD4547_30min_R2 2 ANLACSPLGGGEPSPGAGEPSK 22 0 Q9ULL5;Q9ULL5-2 Q9ULL5 PRR12 Proline-rich protein 12 1 ANLACS(0.995)PLGGGEPS(0.005)PGAGEPSK;ANLACS(0.992)PLGGGEPS(0.008)PGAGEPSK 165.58 7.2002e-32 0.0 23089.8 21528.0 29367.0 42946.0 40467.0 34480.0 26880.7 37159.0 32426.0 36912.0 True False 30431.87610232462 28486.504997014894 28977.574391943075 33045.463209085785 34848.85556126554 32323.960149298942 29273.03022518404 31416.930378872723 34139.972161008984 35619.72211513839 0.8543546747488819 0.7997396752544602 0.8135261218005853 0.9277293939090404 0.97835843437012 0.907473675533287 0.821820847747237 0.8820094181902817 0.9584570045396139 1.0 15.120388640944748 -1.5228787597861673 0.04909434576421383 1.208374894325291 0.3094402852801333 0.42464184315125364 0.05150787298600787 588.6191995252092 2.1915397215583194 9.594775460932647 40.412116540008086 0.029999998997972798 1.5228787597861673 -0.8989346090451578 ANLACS(ph)PLGGGEPSPGAGEPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ANLACSPLGGGEPSPGAGEPSK 22 0 Q9ULL5;Q9ULL5-2 Q9ULL5 PRR12 Proline-rich protein 12 1 ANLACS(0.996)PLGGGEPS(0.004)PGAGEPSK 215.89 2.3130999999999993e-93 0.0 16630.0 15211.0 15468.0 18769.0 20595.0 15235.0 23970.0 17808.0 15361.0 12898.0 True False 19445.13054252809 16721.047554003104 15836.815782716674 17717.433779919 16559.557592444533 14436.04978031531 21699.388072228227 17340.558869135668 15585.625564843094 15236.305299488176 1.2762366046302118 1.0974476571144058 1.0394131301142062 1.1628431848575633 1.0868486333757572 0.9474770619620133 1.4241896342781448 1.1381078633097603 1.0229268355082548 1.0 13.895225481046191 -4.758507351265683 24.627923251617915 1.111145039883422 1.276236871823498 0.14684813352058834 0.12419456277901356 143.19187024583294 1202494.2818394203 0.03090737308777835 0.20865803105481273 1.743783840335568e-05 4.758507351265683 0.16509183194007604 ANLACS(ph)PLGGGEPSPGAGEPSK ddPTM_PC-9_Lapatinib_30min_R1 2 ANLACSPLGGGEPSPGAGEPSK 22 0 Q9ULL5;Q9ULL5-2 Q9ULL5 PRR12 Proline-rich protein 12 1 ANLACS(1)PLGGGEPSPGAGEPSK;ANLACS(0.974)PLGGGEPS(0.026)PGAGEPSK 185.16 2.9641999999999994e-52 7138700.0 32655.0 42849.0 46932.0 37609.0 45501.0 46605.0 37493.0 39887.0 46315.0 37132.0 True False 32189.33371180641 42749.78577313471 43073.43212275902 40374.89131994615 42824.72063840786 44611.81279156127 39434.20408534208 41740.295634652466 41098.51698142847 43550.216724720085 0.73913142419645 0.9816205058944969 0.9890520728065532 0.9270881836284515 0.9833411601393842 1.0243763670236479 0.9054881249984305 0.9584405951063782 0.9437040747974056 1.0 15.410392277866148 -4.759120833662173 24.999567795613018 0.9664725030620759 0.7391311292704148 0.8059918957992036 0.03369560723478942 26.130003670396857 281681.98571731435 0.008376612156786709 0.054460372042042994 1.7413223182442766e-05 4.759120833662173 -0.22734137379166108 ANLQIDQINTDLNLER ddPTM_PC-9_Lapatinib_30min_R1 2 ANLQIDQINTDLNLER 16 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 142.39 5.9876e-05 10690700.0 32062.0 29949.0 33141.0 32618.0 32351.0 32618.0 33302.0 28703.0 27953.0 29522.0 False True 31604.790000549317 29879.654930561075 30416.274907959523 35016.83653045824 30448.177784513155 31223.004176271745 35026.21461206257 30036.646165453167 24804.63878186052 34624.8383644077 0.9127779794356293 0.8629543513270407 0.878452473563766 1.011321299522758 0.8793738605813131 0.9017516225683573 1.0115921479092727 0.8674884153778196 0.7163828036048895 1.0 15.079519715941261 -10.656862431804262 4.2527178173862 1.0000134543816754 0.8982123244918924 0.13915737244646298 0.07865602772554327 113938405.65257876 1.010838007840347 23566.2937643882 0.019319969526594337 2.2036243780268516e-11 10.656862431804262 -0.10180112988978307 ANLQQAIVT(ph)PLKPVDNTYYK ddPTM_PC-9_AZD4547_30min_R2 1 ANLQQAIVTPLKPVDNTYYK 20 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 ANLQQAIVT(0.988)PLKPVDNT(0.01)Y(0.002)YK 79.51100000000001 0.0011525 43400000.0 50128.0 53144.0 51071.0 67581.0 67636.0 72803.0 59798.0 66379.0 56026.0 61725.0 True False 66067.66127282738 70321.75871243786 50393.76517080141 52001.244566041685 58245.90888234256 68250.6169010851 65119.90615592429 56121.650787674385 58987.41998065406 59564.026537627826 1.1091872916128507 1.1806078735797714 0.8460436290177029 0.8730310489199622 0.9778705750449462 1.1458361844958513 1.093275756211456 0.9422071349092087 0.9903195503982674 1.0 15.862153663179273 -5.233282778778074 24.85855749372674 0.987070423312946 1.1448976231872852 0.3589089875210726 0.08614245666280006 844.6260213161153 745690.1801627183 0.02462008568424083 0.0651098593764674 5.844094382758701e-06 5.233282778778074 0.15782719987433913 ANLQQAIVT(ph)PLKPVDNTYYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ANLQQAIVTPLKPVDNTYYK 20 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 ANLQQAIVT(0.998)PLKPVDNT(0.002)YYK 72.421 0.0023799 30098000.0 27160.0 26212.0 27278.0 25896.0 32287.0 25730.0 26434.0 20176.0 21287.0 19439.0 True False 31757.651565548 28814.15413092695 27928.41097239107 24445.131075964753 25960.594124168798 24380.673504923703 23929.980154413064 19646.401378239047 21598.282103952544 22963.136820960666 1.3829840327633172 1.2548004375702493 1.216228043674683 1.064537970859945 1.1305334426467408 1.0617309688574044 1.042104148966698 0.8555626146122112 0.9405632284626598 1.0 14.487032110715248 -4.862449657724959 0.38091400355685684 0.9265208941312628 1.68219379443699 0.854037985146189 0.05659863936015319 2.080707275665514 0.2512106789246191 0.05258250030958791 0.7215146450236208 1.372620062296537e-05 4.862449657724959 0.7556729003057272 ANLQQAIVT(ph)PLKPVDNTYYK ddPTM_PC-9_Lapatinib_30min_R1 2 ANLQQAIVTPLKPVDNTYYK 20 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 ANLQQAIVT(0.999)PLKPVDNT(0.001)YYK;ANLQQAIVT(0.976)PLKPVDNT(0.02)Y(0.003)Y(0.001)K 86.791 0.00053779 72457000.0 204802.0 169148.0 221820.0 187001.0 162570.0 165502.0 119923.0 115651.0 165728.0 102152.0 True False 201881.48592391325 168756.3481984221 203582.81584996145 200753.67735704905 153007.95222491762 158423.86526400544 126132.02615225442 121024.56766473294 147061.967446792 119808.83709101584 1.6850300096857531 1.4085467507728335 1.6992303806046007 1.6756166091866946 1.2771007209483323 1.322305341664027 1.052777317723525 1.0101472529342184 1.227471787703545 1.0 16.870374799568367 -6.67315479673069 1.454139447875468 1.0789727739855934 1.608081143561184 0.8032966139200636 0.11642407781413007 0.17308069496497797 0.7616548181376028 0.05075449718011354 0.04953264346600577 2.1224878032186006e-07 6.67315479673069 0.5291083695755905 ANLS(ph)PSSSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ANLSPSSSFR 10 0 Q8IW93-2;Q8IW93 Q8IW93-2 ARHGEF19 Rho guanine nucleotide exchange factor 19 1 ANLS(0.916)PS(0.081)S(0.003)SFR 110.64 0.0017109000000000002 9618500.0 40634.0 43923.0 73163.0 45182.0 69869.0 55396.0 48110.0 43936.0 55091.0 35448.0 True False 47512.53364191743 48283.38516300564 74907.48339222261 42650.599022020404 56178.67100881312 52490.93624091539 43552.672513763086 42782.72655403998 55896.601653067584 41874.4417937864 1.1346427941868742 1.1530514341129734 1.7888592703183894 1.0185353450693444 1.3415980870973492 1.253531605254839 1.0400776857693113 1.0216906714775207 1.3348620126886537 1.0 15.353782338324743 -7.1334446038103785 5.129933975803107 1.1019737403677055 1.293072795352776 0.15352996899730054 0.21058199972519745 0.4522748797553712 16.979699662787443 0.08133511900362868 0.06267145427086933 7.354537998905963e-08 7.1334446038103785 0.19109905498507063 ANLSPS(ph)SSFR ddPTM_PC-9_AZD4547_30min_R2 2 ANLSPSSSFR 10 0 Q8IW93-2;Q8IW93 Q8IW93-2 ARHGEF19 Rho guanine nucleotide exchange factor 19 1 ANLS(0.283)PS(0.691)S(0.025)SFR;ANLS(0.231)PS(0.384)S(0.384)S(0.001)FR 93.44200000000001 0.017672 7048100.0 71533.0 77461.0 140982.0 165882.0 148947.0 140038.0 106705.0 187689.0 86406.0 112851.0 True False 94279.00602116885 102498.75341758497 139112.48656399778 127640.46775135201 128268.28006236706 131281.4017223763 116201.53828502484 158685.97771415414 90973.24475865495 108900.12083917116 0.8657383049225863 0.9412179952395092 1.277431884299244 1.1720874758243611 1.1778525044228345 1.205521175832843 1.0670469177590425 1.457169895601026 0.8353824041481877 1.0 16.73264602935459 -5.119804920289536 5.215690946682108 1.165718322892285 0.8834578001324532 0.28102852925449373 0.15695566201496805 0.23157074984820766 8.723808630451884 0.03682467027446926 0.10465910593431327 7.589183952351348e-06 5.119804920289536 -0.2822605227598317 ANLSPS(ph)SSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ANLSPSSSFR 10 0 Q8IW93-2;Q8IW93 Q8IW93-2 ARHGEF19 Rho guanine nucleotide exchange factor 19 1 ANLS(0.268)PS(0.725)S(0.007)SFR;ANLS(0.324)PS(0.655)S(0.02)S(0.001)FR 119.03 0.0008238999999999999 13733200.0 55093.0 56872.0 95816.0 59432.0 90496.0 80946.0 65909.0 58347.0 64105.0 55470.0 True False 64419.15676365006 62517.87630604597 98100.61682420364 56102.217721143745 72763.95843097162 76701.04926271099 59665.622380162335 56815.45307375666 65042.414350255 65526.27189972157 0.9831042556828842 0.954088711192367 1.4971188498917254 0.8561789965252415 1.1104547278735202 1.170538885228978 0.9105603088707975 0.8670637200404816 0.9926158236164108 1.0 15.999785831851511 -7.273178429854022 24.41174964183417 0.9314819250372567 1.0969224800819721 0.170317108632279 0.1643449542726373 970.3928394113063 2017955.175136538 0.06785368911818088 0.04617815051184631 5.331158198940779e-08 7.273178429854022 0.16544055504471544 ANNTFYGLSAGVFTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ANNTFYGLSAGVFTK 15 0 P00352 P00352 ALDH1A1 Retinal dehydrogenase 1 0 153.2 0.00071253 2512300.0 9505.7 11374.0 13167.0 13302.0 14364.0 10184.0 7276.2 10086.0 11752.0 13292.0 False True 11114.827263867077 12503.135551852702 13480.951216125573 12556.732065665865 11549.477312836774 9649.933112092613 6586.94566087389 9821.253187000351 11923.85076740031 15701.7343805859 0.7078725823823504 0.796290094380399 0.858564467425575 0.7997035079889894 0.735554240881625 0.6145775287107189 0.4195043363501416 0.6254884300643657 0.7593970499299314 1.0 13.93863630453083 -4.440652260539418 15.386953816920428 0.7171994786239635 0.5368276288720703 0.0 0.14923288775303598 13331594.431277415 43767126.08887942 0.03973153331726769 79390665.86049543 3.625331624278153e-05 4.440652260539418 -0.18037184975189324 ANNTFYGLSAGVFTK ddPTM_PC-9_Lapatinib_30min_R1 2 ANNTFYGLSAGVFTK 15 0 P00352 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ; 143.05 0.00010052 59071000.0 62620.0 58987.0 69149.0 61680.0 61719.0 62036.0 67518.0 62474.0 57334.0 67950.0 False True 61727.02731689841 58850.419225650505 63463.83614285915 66216.15295844823 58088.80976422264 59382.86489297916 71013.75167188873 65376.770112549915 50876.44116621441 79695.0669623162 0.7745401273843716 0.7384449435681875 0.7963333059606816 0.8308689042166002 0.7288883989731753 0.7451259802700002 0.8910683481258329 0.8203364725631427 0.6383888376713621 1.0 16.282202805280107 -11.599501708352593 2.713331888350182 1.3587593656519463 0.7777368326335652 0.5208057719294295 0.06499936979033463 33243792.08914722 9069274.80558767 73978251.85725348 0.016568282083755277 2.51477012080797e-12 11.599501708352593 -0.5810225330183811 ANPFGGASHAK ddPTM_PC-9_AZD4547_30min_R2 2 ANPFGGASHAK 11 0 D6RD47;P62266;D6RDJ2;D6RIX0;D6R9I7 D6RD47 RPS23 40S ribosomal protein S23 0 ; 109.72 0.0017 12348100.0 90042.0 97818.0 132990.0 159900.0 128588.0 121340.0 94149.0 131297.0 109124.0 116708.0 False True 118673.48301005247 129435.75556475318 131226.4657058777 123037.52543037353 110735.775790447 113752.5906182117 102528.07860921985 111008.06555490865 114892.07185893854 112622.0884431506 1.0537318624663625 1.1492928017410171 1.1651929698685903 1.0924812985729744 0.9832509529988359 1.010038014662033 0.9103727343945854 0.9856686826664853 1.0201557567184858 1.0 16.7811302837571 -6.192141334263405 3.4566536002121087 0.9807664643527935 1.125943092256242 0.7300061736822601 0.03900159957136308 0.12463750366244569 2.933028909341983 0.012308756789695304 0.016028465405783777 6.42478598803422e-07 6.192141334263405 0.14517662790344843 ANPFGGASHAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ANPFGGASHAK 11 0 D6RD47;P62266;D6RDJ2;D6RIX0;D6R9I7 D6RD47 RPS23 40S ribosomal protein S23 0 73.632 0.020358 5559800.0 46952.0 45132.0 58189.0 54805.0 61631.0 51117.0 55763.0 57507.0 57993.0 42579.0 False True 54900.04625572938 49612.40669300296 59576.44644301137 51734.45353020735 49554.847971835334 48436.33453366438 50480.72495084116 55997.50218370305 58841.03791302301 50298.235644821456 1.0914904976668245 0.9863647513073531 1.18446394151293 1.028554041050817 0.9852204025955201 0.9629827748968215 1.0036281452754794 1.1133094723068755 1.169842980746405 1.0 15.618220173792777 -10.781605108675773 3.460241675706368 0.9998650516255425 1.054179250979372 0.04929382429566398 0.07491575507407536 56980112.32349936 91811971.40870373 89725.58823271735 0.019687920097132418 1.6534645620874323e-11 10.781605108675773 0.05431419935382942 ANPFGGASHAK ddPTM_PC-9_Lapatinib_30min_R1 2 ANPFGGASHAK 11 0 D6RD47;P62266;D6RDJ2;D6RIX0;D6R9I7 D6RD47 RPS23 40S ribosomal protein S23 0 ; 133.05 6.5048e-05 21869400.0 254398.0 256393.0 235916.0 246399.0 263999.0 259026.0 255881.0 238541.0 249227.0 221795.0 False True 250770.23786912067 255799.3377612393 216519.89714209503 264520.00442296837 248471.09786200378 247948.06179909743 269129.2661446514 249624.48569673387 221156.43078334202 260131.9702267389 0.964011603996778 0.9833444829494693 0.8323463546344179 1.0168684925286373 0.9551732439708539 0.9531625873704735 1.0345874284889711 0.9596071005003869 0.8501701293792354 1.0 17.988884191876807 ANPQVGVAFPHIK ddPTM_PC-9_Lapatinib_30min_R1 1 ANPQVGVAFPHIK 13 0 P13010 P13010 XRCC5 X-ray repair cross-complementing protein 5 0 88.803 0.0053897 2802600.0 24812.0 27582.0 31154.0 30892.0 28894.0 32677.0 32332.0 22988.0 29666.0 26229.0 False True 24458.176330036455 27518.135573633033 28592.63837791772 33163.90073269102 27194.511727789668 31279.480883807475 34005.992758309 24056.10640181992 26324.702683170824 30762.647702054357 0.7950608337397147 0.8945307907223912 0.9294596048703662 1.0780574238567997 0.8840107649763058 1.0168006729056227 1.1054312713153769 0.7819907647355541 0.8557359216324165 1.0 14.90889205912471 -4.870986257365568 2.034913376173915 0.9578683395497469 0.7674179418482131 0.21969889095825046 0.09430177562403566 0.9691073007570573 5.215267331077204 0.026670051459182206 0.32528281328584785 1.3459029425765269e-05 4.870986257365568 -0.19045039770153382 ANPVNRY(ph)MY(ph)VMDTRPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ANPVNRYMYVMDTRPK 16 2 Q9Y217;Q9Y217-2 Q9Y217 MTMR6 Myotubularin-related protein 6 2 ANPVNRY(0.98)MY(0.899)VMDT(0.12)RPK 45.863 0.037177999999999996 4781800.0 11603.0 10977.0 12713.0 15001.0 12251.0 12738.0 13240.0 11804.0 12615.0 11929.0 True False 13567.158730303881 12066.724015534297 13016.126134320988 14160.542603898188 9850.504494539346 12069.996856032578 11985.811350700948 11494.157507371814 12799.470509764715 14091.633270087965 0.9627811390112333 0.856304147592891 0.923677609603286 1.004890088500706 0.6990321352918557 0.8565364017564469 0.8505622535709183 0.8156724835984938 0.9083028393120265 1.0 13.78255121434098 -4.7553764272060475 24.503851257297047 0.871728274482038 0.9627813332761737 0.07344289272254079 0.08491468933570699 408.90086961343394 1652390.9238238563 0.020946357218717862 0.18476251593037393 1.756400583836017e-05 4.7553764272060475 0.09105305879413561 ANQIS(ph)PSNSSLK ddPTM_PC-9_AZD4547_30min_R2 1 ANQISPSNSSLK 12 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 ANQIS(0.688)PS(0.296)NS(0.016)SLK 139.48 7.2537e-05 8121300.0 31445.0 31552.0 34686.0 34849.0 37467.0 36231.0 36904.0 45060.0 36202.0 33644.0 True False 41443.85590336848 41750.56696701107 34226.04097657021 26815.101461682814 32265.353777496126 33965.46984249566 40188.38450747899 38097.01237579066 38115.56381215219 32466.13380043662 1.276525753208444 1.285972860940085 1.0542074762258857 0.8259407056753457 0.9938157088806863 1.0461815395474923 1.237855568344221 1.1734385316701403 1.1740099405257671 1.0 14.986647972395366 -5.260607447838937 24.62415479063807 1.064056441384167 1.2812493306439332 0.3871009098049898 0.10975316960603393 67.31888896223334 1992446.1901650305 0.03256230254370871 0.07664504411066927 5.4877276815130656e-06 5.260607447838937 0.2171928892597661 ANQIS(ph)PSNSSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ANQISPSNSSLK 12 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 ANQIS(0.586)PS(0.354)NS(0.046)S(0.015)LK;ANQIS(0.722)PS(0.276)NS(0.002)SLK 144.51 9.802299999999999e-05 17226300.0 59756.0 90075.0 94224.0 71405.0 72100.0 51493.0 72706.0 56437.0 50762.0 38599.0 True False 69871.51056520207 99017.05071506355 96470.6575065099 67404.4093481335 57972.52257418059 48792.61643175423 65818.76133414393 54955.588549944354 51504.29821773096 45596.69315048412 1.5323810947123524 2.171584031067223 2.1157380248634463 1.4782740740798181 1.271419451030191 1.0700911197819216 1.4434985694449445 1.2052538189243855 1.1295621383715218 1.0 15.476641577878262 -5.955902396349582 3.420823094703783 1.2099311115107088 1.960594630393822 0.7424474654222681 0.1973466717677051 0.11647511345216481 2.8295750585767254 0.058044202195483764 0.08759804567140413 1.106872515342091e-06 5.955902396349582 0.7506635188831132 ANQIS(ph)PSNSSLKNPQAGVPPFSSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ANQISPSNSSLKNPQAGVPPFSSLK 25 1 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 ANQIS(0.25)PS(0.25)NS(0.25)S(0.25)LKNPQAGVPPFSSLK 73.936 9.344e-05 14709000.0 46007.0 33355.0 48842.0 57248.0 52812.0 57130.0 67521.0 57734.0 50486.0 47868.0 True False 53795.07642033012 36666.26396448451 50006.57851431647 54040.580160520185 42463.8677141141 54134.00222838285 61124.92207029304 56218.543674229426 51224.262239871634 56546.089477120484 0.9513491899753126 0.6484314707442379 0.8843507831704257 0.9556908472403901 0.7509602893281543 0.9573429874454253 1.08097522986139 0.9942074543806678 0.9058851410157699 1.0 15.787139635647117 -6.928429883807208 6.947390946104596 0.9981862817903201 0.8373250811398081 0.3934662108447059 0.09370376612716748 0.22420322474477328 17.797578630129113 0.033064435135519786 0.029112235791828662 1.1791528803410932e-07 6.928429883807208 -0.16086120065051202 ANQISPS(ph)NSSLK ddPTM_PC-9_AZD4547_30min_R2 3 ANQISPSNSSLK 12 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 ANQIS(0.087)PS(0.89)NS(0.023)SLK;ANQIS(0.303)PS(0.64)NS(0.052)S(0.005)LK;ANQIS(0.031)PS(0.865)NS(0.103)S(0.001)LK 140.33 7.509199999999999e-05 29385200.0 99395.0 108072.0 105567.0 104252.0 105673.0 127064.0 124982.0 139532.0 113357.0 109969.0 True False 131000.54245556735 143004.16053685412 104167.11260374749 80218.31207734384 91002.12799875486 119118.66799334431 136105.15587778427 117970.5355263833 119348.81959709788 106119.01878195841 1.234468090255647 1.3475827629982446 0.9816064434008622 0.7559277592093792 0.8575477708264146 1.1225006540825273 1.2825708100207565 1.1116813638163776 1.1246694604510301 1.0 16.69532371545391 -5.2625279351150045 24.99116711858294 1.029990751456975 1.2910254395526404 0.35073458915847 0.14229450251514159 116.69643154992292 2679208.717892748 0.04299248863586087 0.09860137823772014 5.463514058013705e-06 5.2625279351150045 0.2610346880956653 ANQISPS(ph)NSSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ANQISPSNSSLK 12 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 ANQIS(0.099)PS(0.898)NS(0.003)SLK;ANQIS(0.214)PS(0.776)NS(0.008)S(0.002)LK 123.28 0.00036229 16340900.0 56867.0 82351.0 61794.0 54778.0 63261.0 45575.0 60697.0 46145.0 38960.0 38158.0 True False 66493.45992555287 90526.26304120092 63267.403315050055 51708.96625267214 50865.46117288824 43184.96676979784 54947.34075177461 44933.74264466894 39529.71629492139 45075.7433414382 1.4751494927522433 2.008314368894278 1.4035798108932844 1.147157260635478 1.1284442008553088 0.9580533468451495 1.2190002133866404 0.9968497314466089 0.8769620501983304 1.0 15.460063662802495 -5.615964573153258 2.586506474930667 1.0456576979530408 1.7440922643708416 0.7674666258458603 0.15388702482521552 0.1180675219061911 1.5872383334056308 0.04216261471384555 0.08682955080813826 2.421226546190844e-06 5.615964573153258 0.6984345664178009 ANQISPS(ph)NSSLK ddPTM_PC-9_Lapatinib_30min_R1 4 ANQISPSNSSLK 12 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 ANQIS(0.077)PS(0.908)NS(0.012)S(0.002)LK;ANQIS(0.253)PS(0.707)NS(0.032)S(0.008)LK;ANQIS(0.227)PS(0.766)NS(0.006)S(0.001)LK;ANQIS(0.054)PS(0.723)NS(0.198)S(0.026)LK 150.9 5.5997e-05 27242000.0 49760.1 103722.0 105762.0 104836.0 131052.0 115452.0 108283.0 122833.0 114174.0 110186.0 True False 49050.511849115246 103481.83808166055 97066.65661312598 112545.98916264379 123343.77901814537 110514.38709175693 113889.36390721178 128540.2696039128 101314.52181447936 129231.5032863837 0.37955537621826446 0.8007477700877582 0.751106766885016 0.8708866360026476 0.9544404876635164 0.8551659949884769 0.8812817386703848 0.9946511983154829 0.7839769656626305 1.0 16.97959827894904 -4.563888298952265 1.293854238808718 0.8973936837567427 2.9539996232237836e-31 0.7954192349661293 0.07681871713435502 0.9436519870144489 0.969873991850685 0.021492185654659955 1.283203302953983 2.7296797693515592e-05 4.563888298952265 -0.8973936837567427 down ANQISPS(ph)NSSLKNPQAGVPPFSSLK ddPTM_PC-9_AZD4547_30min_R2 2 ANQISPSNSSLKNPQAGVPPFSSLK 25 1 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 ANQIS(0.07)PS(0.31)NS(0.31)S(0.31)LKNPQAGVPPFSSLK;ANQIS(0.014)PS(0.328)NS(0.328)S(0.328)LKNPQAGVPPFSSLK 80.868 3.1754e-05 31377000.0 99222.0 66174.0 120694.0 163372.0 139366.0 118117.0 99008.0 127120.0 95458.0 113792.0 True False 130772.5320541907 87563.45139689998 119093.51869994137 125709.1094722386 120017.43653226882 110731.12531771272 107819.52019608924 107476.52492699769 100503.71499863065 109808.17671558924 1.190917980478818 0.7974219590558849 1.0845596590534583 1.1448064546034116 1.0929735846823345 1.0084050990529965 0.9818897227967753 0.9787661369277564 0.915266221557819 1.0 16.744625961091536 -7.109119465614703 2.867153682872551 0.9660519202791935 1.053008249455123 0.1578300546513287 0.09988900068436588 0.594558765557991 9.429787367406782 0.042655420107508286 0.03211613020000859 7.778225583787514e-08 7.109119465614703 0.08695632917592944 ANQISPS(ph)NSSLKNPQAGVPPFSSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ANQISPSNSSLKNPQAGVPPFSSLK 25 1 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 ANQIS(0.018)PS(0.327)NS(0.327)S(0.327)LKNPQAGVPPFSSLK 74.876 8.327100000000001e-05 11841000.0 62249.0 55583.0 74634.0 71873.0 79883.0 81081.0 86760.0 85843.0 78942.0 61331.0 True False 72786.5262262076 61100.91290475019 76413.55761102134 67846.18882540987 64230.49959491366 76828.96962505704 78541.46471199518 83589.71220817664 80096.37740640885 72449.82480407116 1.0046473738624901 0.8433548744940065 1.054710039916169 0.9364575968111576 0.8865514826104087 1.0604438289923899 1.084080809365625 1.1537600323290154 1.1055427342028301 1.0 16.14469458065528 -6.904022367790063 5.42305219273387 1.095221891402508 0.9455772877369756 0.5209843878919515 0.0650313618990519 0.15750708855423778 7.225863132578491 0.022651303639770283 0.0199242153192824 1.2473192709811914e-07 6.904022367790063 -0.14964460366553245 ANQISPS(ph)NSSLKNPQAGVPPFSSLK ddPTM_PC-9_Lapatinib_30min_R1 2 ANQISPSNSSLKNPQAGVPPFSSLK 25 1 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 ANQIS(0.017)PS(0.328)NS(0.328)S(0.328)LKNPQAGVPPFSSLK;ANQIS(0.033)PS(0.711)NS(0.128)S(0.128)LKNPQAGVPPFSSLK 88.23899999999999 3.6691e-06 27219000.0 157045.0 101631.0 135923.0 137956.0 126305.0 125373.0 90781.0 96145.0 141248.0 93187.0 True False 154805.50950147427 101395.67966368995 124747.93561795329 148101.744447725 118875.98822518432 120011.08904873756 95481.19598515554 100612.24769457866 125339.16283262044 109294.24878612767 1.416410389575075 0.9277311550226762 1.141395242690822 1.3550735385677772 1.0876692007628568 1.0980549331884895 0.8736159225724477 0.9205630562634785 1.1468047424699377 1.0 16.737857960844295 -6.843500180298608 2.446771664534252 0.9811057097434408 1.1838035785285466 0.30442968972619444 0.14257772163488108 0.37846613874284074 4.625332967741402 0.05576795940682104 0.04903332937645226 1.4338371207940671e-07 6.843500180298608 0.20269786878510576 ANS(ph)DTDLVTSESR ddPTM_PC-9_AZD4547_30min_R2 1 ANSDTDLVTSESR 13 0 C9JHL2;A0A2R8Y6F3;Q9P2P5 C9JHL2 HECW2 E3 ubiquitin-protein ligase HECW2 1 ANS(1)DTDLVTSESR 128.71 0.00079708 0.0 7133.2 4916.5 8445.8 9473.4 10202.0 7531.7 7390.1 11289.0 5608.0 9006.8 True False 9401.409220222868 6505.662477602371 8333.80317361231 7289.453992570983 8785.628399338499 7060.741608366437 8047.8045834793165 9544.544445412806 5904.42743104109 8691.474673456556 1.0816817137987442 0.7485107788981339 0.958848007584195 0.8386901264100449 1.0108328827292663 0.8123755603786872 0.9259423614334419 1.0981501763517179 0.67933551587891 1.0 13.08538526303511 -7.506952906264073 24.601646302185124 0.9356549397729592 0.902000707901036 0.0010121538551234321 0.13386784994682002 3815.66117962768 5894324.495849891 0.053668446852675834 0.03494496896020458 3.112053781626233e-08 7.506952906264073 -0.03365423187192318 ANS(ph)DTDLVTSESR ddPTM_PC-9_Lapatinib_30min_R1 1 ANSDTDLVTSESR 13 0 C9JHL2;A0A2R8Y6F3;Q9P2P5 C9JHL2 HECW2 E3 ubiquitin-protein ligase HECW2 1 ANS(0.998)DT(0.002)DLVTSESR 105.53 0.0012190999999999999 2157700.0 11033.0 9723.0 9593.5 8535.6 10617.0 10576.0 8768.2 10862.0 11110.0 6658.5 True False 10875.667396795598 9700.486990879344 8804.759461980924 9163.33649792689 9992.528933825117 10123.689133860145 9222.174492867907 11366.688173680532 9858.674806513443 7809.412853106449 1.3926357334878827 1.2421531776259798 1.1274547302846902 1.17337073481547 1.2795493235897066 1.296344465875321 1.1809049753592533 1.4555112384869062 1.2624092223004748 1.0 12.930998368784243 -10.27853818231808 4.618506192567448 0.999999528965233 1.264302631056448 0.42070135370386974 0.09419902733125782 67412757.05678342 151158910.75661874 544.260995160259 0.0244326712783061 5.26576917250136e-11 10.27853818231808 0.264303102091215 ANS(ph)FESR ddPTM_PC-9_AZD4547_30min_R2 1 ANSFESR 7 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 ANS(0.77)FES(0.23)R 75.652 0.032405 7944100.0 17764.0 17089.0 37091.0 52378.0 56438.0 32010.0 33373.0 38538.0 32384.0 42168.0 True False 23412.58248584632 22612.685056391107 36599.14910517115 40303.061332033125 48602.55789079261 30008.40963976388 36343.13234793238 32582.83761514028 34095.75212675369 40691.71115494026 0.5753649040881847 0.5557074012024134 0.8994251671013288 0.9904489191563537 1.1944092915073177 0.7374575506422429 0.8931335477525147 0.8007241939537972 0.837904112631897 1.0 15.312447328991297 -5.27227631115525 6.749334800808444 0.9175935521964266 0.564084986973472 0.584650926774529 0.11925345404587043 0.09802053343607885 25.666168860411098 0.03304892340683848 0.07545340714997276 5.3422436171269105e-06 5.27227631115525 -0.3535085652229546 ANS(ph)FVGTAQYVSPELLTEK ddPTM_PC-9_AZD4547_30min_R2 2 ANSFVGTAQYVSPELLTEK 19 0 E9PER6;Q6A1A2;O15530-4;O15530-5;O15530;O15530-2 E9PER6 PDPK1;PDPK2P Putative 3-phosphoinositide-dependent protein kinase 2;3-phosphoinositide-dependent protein kinase 1 1 ANS(0.869)FVGT(0.131)AQYVSPELLTEK;ANS(0.957)FVGT(0.042)AQYVSPELLTEK 92.098 0.00089837 70384000.0 159688.0 136396.0 183466.0 238340.0 195900.0 189037.0 186669.0 206456.0 163794.0 189484.0 True False 210465.46228326007 180483.3396308455 181033.12096544515 183394.39531629285 168702.66648014207 177216.48650646777 203282.17937423082 174552.96908691156 172451.8164479217 182850.22283444076 1.1510265561657158 0.9870556176147605 0.9900623480746814 1.0029760558856131 0.9226276231169354 0.9691893384615999 1.111741491057902 0.9546226763144727 0.943131562951749 1.0 17.480302859289168 -4.761370901234424 23.37028679116254 0.9873574701073267 1.1510268795611898 0.5087418323770467 0.04840464634791314 0.6201279238515663 207887.90733318974 0.012390004207510354 0.06919658928329758 1.7323239063717427e-05 4.761370901234424 0.1636694094538631 ANS(ph)FVGTAQYVSPELLTEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ANSFVGTAQYVSPELLTEK 19 0 E9PER6;Q6A1A2;O15530-4;O15530-5;O15530;O15530-2 E9PER6 PDPK1;PDPK2P Putative 3-phosphoinositide-dependent protein kinase 2;3-phosphoinositide-dependent protein kinase 1 1 ANS(0.999)FVGT(0.001)AQYVSPELLTEK 116.04 7.0124e-05 96979000.0 31851.0 33205.0 35169.0 36262.0 35505.0 31927.0 34148.0 32054.0 31407.0 28445.0 True False 37242.745214074734 36501.37295579996 36007.562339175216 34230.357702990215 28548.0501247751 30252.691915728697 30913.254229889426 31212.616464020368 31866.267958793516 33601.85332950391 1.1083539008657586 1.0862904673103297 1.071594533375306 1.018704455594253 0.8495974863299773 0.9003280747364462 0.9199865830836844 0.9288956819716344 0.9483485225147843 1.0 15.036253187420922 -5.999088030576506 3.5324400596575205 0.9195907417042305 1.0869947619774523 0.798164223787333 0.03718962968639929 0.09716071751798686 2.6018547102814695 0.011153444299424123 0.016238598818679947 1.002102093506991e-06 5.999088030576506 0.16740402027322177 ANS(ph)FVGTAQYVSPELLTEK ddPTM_PC-9_Lapatinib_30min_R1 1 ANSFVGTAQYVSPELLTEK 19 0 E9PER6;Q6A1A2;O15530-4;O15530-5;O15530;O15530-2 E9PER6 PDPK1;PDPK2P Putative 3-phosphoinositide-dependent protein kinase 2;3-phosphoinositide-dependent protein kinase 1 1 ANS(0.957)FVGT(0.04)AQY(0.002)VS(0.001)PELLTEK 71.309 0.006405500000000001 39700000.0 63213.0 56968.0 57741.0 57447.0 69742.0 65433.0 57260.0 54710.0 70688.0 46982.0 True False 62311.57102815557 56836.09409610347 52993.75786670563 61671.84401757417 65639.91267804749 62634.58312177295 60224.64262466822 57252.02632867441 62726.37306236029 55102.77610042009 1.1308245325897568 1.0314560920220164 0.9617257353809007 1.1192148269477842 1.191226963926906 1.1366865256956709 1.0929511521327704 1.039004391073464 1.1383523209075137 1.0 15.749837383743685 -4.452748519961058 13.406743243892288 1.0833788460578402 1.5442247410024448 0.04723556805023921 0.06729593814956962 784792.2539672405 4405190.01521434 0.017946921559432387 9721345.445274506 3.5257497195843644e-05 4.452748519961058 0.4608458949446046 ANS(ph)GGVDLDSSGEFASIEK ddPTM_PC-9_AZD4547_30min_R2 4 ANSGGVDLDSSGEFASIEK 19 0 Q92766;Q92766-2;Q92766-5;Q92766-3;A0A087X055 Q92766 RREB1 Ras-responsive element-binding protein 1 1 ANS(0.992)GGVDLDS(0.003)S(0.005)GEFASIEK;ANS(0.992)GGVDLDS(0.003)S(0.005)GEFASIEK;ANS(0.998)GGVDLDS(0.001)S(0.001)GEFASIEK;ANS(1)GGVDLDSSGEFASIEK 149.44 6.2264e-06 22080300.0 51322.0 54656.0 63980.0 91065.0 72350.0 67604.0 54948.3 76632.0 60250.0 65662.5 True False 67641.32843608446 72322.48314366622 63131.58339621062 70071.37119022483 62305.4513519056 63376.71119295836 59838.5922510381 64790.285228175635 63434.69199718714 63363.67586110945 1.0675095394457772 1.14138711431758 0.9963371369835367 1.1058602620185478 0.9832991931919569 1.0002057224690923 0.9443674382496655 1.0225146244702288 1.0011207704589828 1.0 15.951368411191202 -6.270460165798847 24.861770302076625 0.9910805478208586 1.0765004581366218 0.5397886938351075 0.03882482367467262 465.6603135367229 1283382.3893448834 0.011686545985763871 0.013446892391161046 5.364630744555621e-07 6.270460165798847 0.08541991031576313 ANS(ph)GGVDLDSSGEFASIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ANSGGVDLDSSGEFASIEK 19 0 Q92766;Q92766-2;Q92766-5;Q92766-3;A0A087X055 Q92766 RREB1 Ras-responsive element-binding protein 1 1 ANS(1)GGVDLDSSGEFASIEK;ANS(1)GGVDLDSSGEFASIEK 217.02 7.9508999999999995e-28 9272200.0 20102.6 25472.5 20647.5 30321.0 35411.0 32167.0 33009.0 29117.0 28800.0 22556.0 True False 23505.573135551735 28001.241458112177 21139.814706079807 28622.212672008325 28472.468749990432 30480.105893232834 29882.148555535317 28352.709602011622 29221.14551575297 26645.22424680225 0.8821683359776074 1.0508915668620304 0.7933810017987311 1.0741967268465882 1.0685768108484759 1.1439237895282799 1.1214823444062978 1.0640822287474008 1.0966747828838357 1.0 14.70158935445217 -5.892109348169843 9.483860861993085 1.0889089281584554 0.9232900395372757 0.5624327786602314 0.06924284351478247 0.20401119992618905 16.59550516279473 0.018464301325620536 0.027431611399217164 1.2820077536607927e-06 5.892109348169843 -0.16561888862117968 ANS(ph)GGVDLDSSGEFASIEK ddPTM_PC-9_Lapatinib_30min_R1 3 ANSGGVDLDSSGEFASIEK 19 0 Q92766;Q92766-2;Q92766-5;Q92766-3;A0A087X055 Q92766 RREB1 Ras-responsive element-binding protein 1 1 ANS(1)GGVDLDSSGEFASIEK;ANS(1)GGVDLDSSGEFASIEK;ANS(0.95)GGVDLDS(0.025)S(0.025)GEFASIEK 196.75 7.71e-15 10488100.0 50207.0 54822.0 53248.0 40257.0 45300.0 62212.0 56919.0 57127.0 63295.0 37276.1 True False 49491.03897316386 54695.06302725362 48870.15498322407 43217.634073415225 42635.54306322668 59551.337783255185 59865.98731319404 59781.32897236672 56166.050574101624 43719.2242177189 1.1320200634554194 1.2510529179309258 1.1178184393175385 0.9885270117830595 0.9752127085079196 1.3621316217024664 1.3693286736989045 1.3673922637478557 1.284699158759047 1.0 15.41598018066952 -6.772752223734882 24.970084760154172 1.3054610269992042 1.0972939804814485 0.3383377201217048 0.12524645289960246 228.9770728574571 505402.6252579813 0.04459787696831864 0.03967415516702364 1.6875155221681448e-07 6.772752223734882 -0.20816704651775564 ANS(ph)LDNER ddPTM_PC-9_AZD4547_30min_R2 1 ANSLDNER 8 0 F8VW41;Q86VP3-4;Q86VP3;Q86VP3-3;Q86VP3-2 F8VW41 PACS2 Phosphofurin acidic cluster sorting protein 2 1 ANS(1)LDNER 77.67399999999999 0.023207 7145800.0 26180.0 32898.0 49646.0 41090.0 41094.0 43662.0 40734.0 51085.0 34399.0 46909.0 True False 34504.69542217161 43531.63514454644 48987.661601879845 31617.33533417165 35388.80743407335 40931.80823778103 44359.24708778588 43190.98706651723 36217.260913049664 45266.73018798839 0.7622528792973762 0.9616695300005927 1.082200136798898 0.6984673998512348 0.7817840450835973 0.904236026498825 0.9799525369640392 0.9541441780121781 0.8000856426484275 1.0 15.466163477786479 -6.993303609128067 24.6542232959339 0.9314914257460679 0.8643739548404057 0.09195764551915109 0.11247755234189082 443.76988969378294 1633823.3113214425 0.04198893847083764 0.03693871308778434 1.015538496060201e-07 6.993303609128067 -0.06711747090566222 ANS(ph)LDNER ddPTM_PC-9_Lapatinib_30min_R1 1 ANSLDNER 8 0 F8VW41;Q86VP3-4;Q86VP3;Q86VP3-3;Q86VP3-2 F8VW41 PACS2 Phosphofurin acidic cluster sorting protein 2 1 ANS(1)LDNER 86.463 0.012457 9249600.0 33354.0 35045.0 43079.0 33573.0 44577.0 36941.0 46050.0 44883.0 37671.0 35096.0 True False 32878.36584362552 34963.8554556584 39537.2109097489 36042.070416244875 41955.06850175398 35361.119543676934 48434.24367561949 46968.42803344719 33428.095286783806 41162.296837519534 0.798749544356252 0.8494145891244037 0.9605200376892146 0.8756088261671647 1.0192596556835436 0.8590657533824786 1.176665234858118 1.141054597095159 0.8121047136590788 1.0 15.329035865757223 -5.220347954929094 0.5741915349931578 1.0236503481668235 0.7245482296647756 0.2790332753948095 0.10776957503453867 3.257540481993355 1.1576607589875811 0.06349651605987215 0.607260220561768 6.0207701118930935e-06 5.220347954929094 -0.29910211850204793 ANS(ph)LDNERCPDAR ddPTM_PC-9_AZD4547_30min_R2 1 ANSLDNERCPDAR 13 1 F8VW41;Q86VP3-4;Q86VP3;Q86VP3-3;Q86VP3-2 F8VW41 PACS2 Phosphofurin acidic cluster sorting protein 2 1 ANS(1)LDNERCPDAR 51.727 0.045711 6391200.0 22088.0 19414.0 25441.0 42663.0 39168.0 31134.0 23307.0 28922.0 23558.0 29172.0 True False 29111.524541059058 25689.195838538068 25103.635717145906 32827.704486779396 33730.19928889338 29187.18605824458 25381.27784835827 24452.76946144291 24803.22778538979 28150.69715926573 1.034131566133419 0.9125598450794508 0.8917589349606253 1.1661417939688306 1.1982012061037421 1.0368192976932258 0.9016216438534663 0.8686381485722582 0.8810875142829588 1.0 14.78088303101165 -7.258526611097172 8.390723564554028 0.9017552769017894 1.0404305448997424 0.297555796152829 0.0950646157096894 0.1616892404586745 143.53143463104738 0.04286698539756076 0.03120296650085544 5.514084141733541e-08 7.258526611097172 0.13867526799795304 ANS(ph)LGDLYAQK ddPTM_PC-9_AZD4547_30min_R2 3 ANSLGDLYAQK 11 0 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 ANS(1)LGDLYAQK;ANS(0.999)LGDLY(0.001)AQK;ANS(1)LGDLYAQK 146.77 0.00023882 39385100.0 160604.0 142762.0 176776.0 240597.0 202475.0 182643.0 170306.0 211826.0 162321.0 168775.0 True False 211672.73122927576 188907.02463693052 174431.83473661364 185131.07883659517 174364.84122290404 171222.30433725117 185462.9040735616 179093.15897723552 170900.95667511068 162866.23862111184 1.2996722526496494 1.159890633174131 1.0710128521013353 1.1367062959394534 1.070601511394527 1.0513063099319109 1.1387437055326004 1.0996334199985647 1.049333232731497 1.0 17.313328045630215 -4.680740376800963 1.635924191649602 1.0822653103599902 1.4216217062886767 0.7468541331585179 0.039730488327288344 0.6425651509271866 1.3859705350492297 0.010680455308562242 0.37531845670226555 2.0857373736856015e-05 4.680740376800963 0.3393563959286865 ANS(ph)LGDLYAQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ANSLGDLYAQK 11 0 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 ANS(1)LGDLYAQK;ANS(1)LGDLYAQK;ANS(1)LGDLYAQK 105.14 0.0025954999999999997 22688700.0 157163.0 164130.0 172278.0 180274.0 205144.0 185093.0 190577.0 184613.0 160398.0 140151.0 True False 183767.59178925684 180423.7417026187 176385.76088795328 170173.83223619335 164947.5058385257 175386.39724239585 172524.16690200428 179767.10436364266 162743.5173067967 165559.26686529437 1.1099807052104036 1.0897834057782985 1.0653934643928316 1.027872588821341 0.9963048820017644 1.0593571750054753 1.0420689229215834 1.0858172288834087 0.982992498023148 1.0 17.336988239544652 -5.405386115329301 2.108521192354787 1.0320745510556761 1.104522250456503 0.49194832367890606 0.029431785774798026 0.3031688972057998 2.5569978034905403 0.008376675582460042 0.024862385003652586 3.9320033997860525e-06 5.405386115329301 0.07244769940082696 ANS(ph)LGDLYAQK ddPTM_PC-9_Lapatinib_30min_R1 4 ANSLGDLYAQK 11 0 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 ANS(1)LGDLYAQK;ANS(1)LGDLYAQK;ANS(1)LGDLYAQK;ANS(0.997)LGDLY(0.003)AQK 135.14 6.8569e-05 46226000.0 243795.0 208327.0 221243.0 191736.0 223049.0 210480.0 183861.0 177378.0 211878.0 155740.0 True False 240318.43859347218 207844.6316310725 203053.2545626776 205836.90505254606 209929.6963512061 201478.26105284438 193380.42294121784 185619.62943022474 188014.0684657478 182659.45148949476 1.3156638577078699 1.1378805199304247 1.1116493173875306 1.1268888818730758 1.1492955586986404 1.1030267495598602 1.0586937679068835 1.0162059938130288 1.0293147544930683 1.0 17.478796880555237 -1.5228787452803376 0.22830638351270155 0.9983944810414287 2.445121112255198 0.7990647861238138 0.03875070934051798 24.645928772245842 0.3213753809562743 0.061776888779400685 13.292406072838094 0.029999999999999995 1.5228787452803376 1.4467266312137692 ANS(ph)PEKPPEAGAAHKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ANSPEKPPEAGAAHKPR 17 2 F8WDB4;Q9UFC0 F8WDB4 LRWD1 Leucine-rich repeat and WD repeat-containing protein 1 1 ANS(1)PEKPPEAGAAHKPR;ANS(1)PEKPPEAGAAHKPR 48.623000000000005 0.037488 62569100.0 104124.0 105411.0 88527.0 99562.0 112232.0 100104.0 117157.0 111761.0 103385.0 90313.0 True False 121750.13665725748 115875.50744297038 90637.8194205171 93983.86392435928 90240.94526415301 94854.37001697946 106059.0408167726 108827.3921705676 104896.81003979602 106686.03198268535 1.1412003464241407 1.0861356945188143 0.8495753168064888 0.8809387899965426 0.8458552969595747 0.8890983032565489 0.9941230247834645 1.0200716077642646 0.9832290890415747 1.0 16.703011776105797 -5.114469468534094 5.219542620824922 0.929690077100723 1.1284640443689304 0.5838877105360143 0.061651259204564234 0.15910427881450243 6.071671709013666 0.017922059718353627 0.05102290135540498 7.68299466230669e-06 5.114469468534094 0.1987739672682074 ANS(ph)PSLFGTEGKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ANSPSLFGTEGKPK 14 1 Q5JPT2;Q96B97-2;Q96B97;Q96B97-3 Q5JPT2 SH3KBP1 SH3 domain-containing kinase-binding protein 1 1 ANS(0.709)PS(0.291)LFGTEGKPK;ANS(0.762)PS(0.238)LFGTEGKPK 123.76 0.00019415 36692000.0 49753.0 51768.0 54668.0 59036.0 58998.0 58908.0 57199.0 57966.0 51998.0 33869.0 True False 58175.20023345765 56907.18491720687 55971.49244954454 55728.4043172944 47437.76542068671 55818.76077839276 51780.69663510147 56444.453920053755 52758.37237944868 40009.181593143505 1.4540462443107636 1.4223531362350892 1.398966192778523 1.3928903841123494 1.1856719765749035 1.395148777248635 1.2942203407623636 1.41078751607673 1.3186566252704865 1.0 15.288043497520912 -13.313971373506915 0.22525403133991645 2.302678395964266e-12 1.409657319668336 0.7135049905594741 0.0706987479900614 49.25189595141016 0.8039596266208312 22.82482207723991 0.13706590351120884 4.8532048897692736e-14 13.313971373506915 1.4096573196660334 ANS(ph)SGLYK ddPTM_PC-9_Lapatinib_30min_R1 1 ANSSGLYK 8 0 J3KR59;J3KR68;Q9UID6 J3KR59 ZNF639 Zinc finger protein 639 1 ANS(0.988)S(0.012)GLYK 70.977 0.036667 4389400.0 31447.0 22279.0 26158.0 14215.0 28250.0 20868.0 22352.0 31069.0 17938.0 21048.0 True False 30998.560013326485 22227.41434431769 24007.390212800008 15260.418519849907 26588.390541636945 19975.524285683936 23509.27719082405 32512.579162960817 15917.633544485894 24686.118755302934 1.2557081297629076 0.9004013374740378 0.9725056599933465 0.6181781215231231 1.0770583583912061 0.8091804338984193 0.9523278010551545 1.3170389191284535 0.644800979135959 1.0 14.591412407903883 -9.969789879002821 15.453330757800124 1.0000210280361128 0.9496555838985754 0.004819797954856209 0.21688068070106917 0.0 0.0 0.2002248987453523 0.048561670965040514 1.0720378547218187e-10 9.969789879002821 -0.05036544413753741 ANS(ph)TSDSVFTETPSPVLK ddPTM_PC-9_AZD4547_30min_R2 4 ANSTSDSVFTETPSPVLK 18 0 C9JEZ4;Q9UKI2 C9JEZ4 CDC42EP3 Cdc42 effector protein 3 1 ANS(0.954)T(0.013)S(0.033)DSVFTETPSPVLK;ANS(0.693)T(0.228)S(0.075)DS(0.005)VFTETPSPVLK;ANS(0.961)T(0.039)SDSVFTETPSPVLK;ANS(0.992)T(0.004)S(0.004)DSVFTETPSPVLK 235.54 2.7524999999999994e-43 43659400.0 127165.0 108362.0 165833.0 250929.0 188235.0 170090.0 211129.0 249260.0 216208.0 193625.0 True False 167600.82480368394 143387.8973655951 163633.94606664276 193081.1958644037 162101.81942261133 159454.24541166628 229919.0719889317 210742.59442497988 227636.31348262008 186846.24768486302 0.8969986118552478 0.7674111690347388 0.8757679005822456 1.0333694053629412 0.8675679679477111 0.853398167677435 1.2305254980379152 1.127893104818571 1.2183081881663156 1.0 17.51149206571342 -7.255498949405138 24.994745727385272 1.1548394598271625 0.8830752696001368 0.6955130320997616 0.08473075632710092 266.17146648679744 1119937.00753234 0.033201598142708594 0.025033104433676043 5.552659603529772e-08 7.255498949405138 -0.2717641902270257 ANS(ph)TSDSVFTETPSPVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ANSTSDSVFTETPSPVLK 18 0 C9JEZ4;Q9UKI2 C9JEZ4 CDC42EP3 Cdc42 effector protein 3 1 ANS(0.691)T(0.296)S(0.013)DSVFTETPSPVLK;ANS(0.759)T(0.2)S(0.038)DS(0.002)VFTETPSPVLK 191.07 3.5377e-11 15069500.0 38977.0 39272.0 36559.0 47169.0 54708.0 55329.0 59577.0 80647.0 58132.0 43411.0 True False 45575.03626915923 43170.66462039381 37430.7052107796 44526.27385396131 43988.36012466399 52427.44983886217 53933.4352598724 78530.10170255972 58982.070525060815 51281.070658713106 0.8887302016853588 0.841844057970321 0.7299127091142312 0.8682789435168687 0.8577894252133751 1.0223548214852702 1.0517220987606006 1.5313662662231637 1.1501723690131116 1.0 15.646138762759831 -7.1433592128024195 1.7420229126725864 1.247944848123701 0.8309761358232981 0.5830864833603775 0.13782960361346575 0.22945204093806776 1.3730524957440793 0.06754991115281114 0.04585005010839083 7.188541548006227e-08 7.1433592128024195 -0.4169687123004029 ANSALT(ph)PPKPESGLTLQESNTPGLR ddPTM_PC-9_AZD4547_30min_R2 1 ANSALTPPKPESGLTLQESNTPGLR 25 1 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 ANS(0.044)ALT(0.927)PPKPES(0.022)GLT(0.006)LQESNTPGLR 74.0 0.00013916 9664200.0 37727.0 37549.0 46159.0 58769.0 51384.0 40666.0 42163.0 47307.0 45245.0 45025.0 True False 49723.401229651216 49685.979939284276 45546.901500245185 45220.71502199887 44250.21855240243 38123.14859139763 45915.4253194461 39996.79015671391 47636.55833050178 43448.688454543386 1.1444166210373075 1.1435553455489555 1.0482917464331973 1.0407843511619321 1.0184477397677405 0.8774292147226168 1.0567735633144242 0.9205523015627757 1.096386565968264 1.0 15.407025007942766 -5.476281035606881 1.267360270498351 0.9898056025303351 1.1612075495037035 0.4764871075371956 0.05950377258999136 0.4673175578143214 1.3092719326660318 0.01865162580488573 0.07541490783902265 3.33978849565683e-06 5.476281035606881 0.1714019469733684 ANSALT(ph)PPKPESGLTLQESNTPGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ANSALTPPKPESGLTLQESNTPGLR 25 1 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 ANS(0.018)ALT(0.714)PPKPES(0.173)GLT(0.055)LQES(0.018)NT(0.021)PGLR 57.543 0.0035601 58355000.0 36134.0 36886.0 42584.0 53210.0 50626.0 48382.0 48857.0 50482.0 45108.0 37006.0 True False 42250.772520968734 40547.79830891847 43599.36406071931 50228.81620914758 40706.19872178183 45844.76274835673 44228.91126595139 49156.9009901003 45767.61916404806 43714.894860665205 0.9665074720100976 0.9275510884369873 0.9973571753903531 1.14900919627611 0.9311745768010389 1.0487217890945446 1.0117583813692002 1.124488601580324 1.046957091168253 1.0 15.415837308710094 -5.5237108075861 24.999799939261155 1.0461091790723387 0.9508854758468018 0.31072045501952006 0.05834708989835063 30.536455589881992 917484.9214662797 0.015477811001970786 0.02711740267616543 2.994257819676557e-06 5.5237108075861 -0.09522370322553686 ANSALTPPKPES(ph)GLTLQESNTPGLR ddPTM_PC-9_AZD4547_30min_R2 2 ANSALTPPKPESGLTLQESNTPGLR 25 1 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 ANS(0.003)ALT(0.149)PPKPES(0.607)GLT(0.066)LQES(0.087)NT(0.087)PGLR;ANS(0.013)ALT(0.055)PPKPES(0.6)GLT(0.196)LQES(0.067)NT(0.069)PGLR 52.227 0.0074598 446723000.0 35176.0 31331.0 42188.0 50267.0 47686.0 47626.0 39832.0 44630.0 45780.0 44670.0 True False 46361.23629374746 41458.13303890162 41628.5595548505 38678.71976740825 41065.622020276016 44647.93869114013 43376.97083519144 37733.458995373694 48199.83733827763 43106.1168964898 1.0755140947878497 0.9617691414528137 0.9657227918444303 0.8972907455405225 0.9526634495722822 1.0357680511643552 1.0062834223586419 0.8753620532784847 1.118166998294449 1.0 15.395604986452383 -6.731398093058193 24.967947910725137 0.9992742464681313 0.9657590731862001 0.05740736517056744 0.06913224278906072 713.5743015964842 593064.8725457765 0.02262549261344346 0.02262249360993499 1.856102291637254e-07 6.731398093058193 -0.03351517328193121 ANSALTPPKPES(ph)GLTLQESNTPGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ANSALTPPKPESGLTLQESNTPGLR 25 1 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 ANS(0.015)ALT(0.163)PPKPES(0.459)GLT(0.341)LQES(0.016)NT(0.006)PGLR 50.055 0.012119 59289000.0 60865.0 68165.0 61640.0 74495.0 72419.0 80169.0 75287.0 83986.0 77254.0 61213.0 True False 71168.2423614536 74931.97071320907 63109.73137100178 70321.28666604879 58229.01681414133 75964.79651054129 68155.2703293219 81781.45649052282 78383.6935997908 72310.43233815863 0.9842043542021212 1.036253944144475 0.8727610848165046 0.9724915809822899 0.8052643986670447 1.0505371639225316 0.942537170993458 1.1309772856573874 1.0839887283930298 1.0 16.141916181591423 -7.74978053297118 24.923380343128454 1.080612254001295 0.9511329523143602 0.3506484993572845 0.07430797142539586 208.04257280887987 444739.68960775534 0.034829148945846294 0.019888868519699968 1.779178275537246e-08 7.74978053297118 -0.12947930168693478 ANSALTPPKPES(ph)GLTLQESNTPGLR ddPTM_PC-9_Lapatinib_30min_R1 3 ANSALTPPKPESGLTLQESNTPGLR 25 1 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 ANS(0.002)ALT(0.041)PPKPES(0.75)GLT(0.168)LQES(0.019)NT(0.019)PGLR;ANS(0.003)ALT(0.05)PPKPES(0.931)GLT(0.016)LQESNTPGLR;ANS(0.022)ALT(0.276)PPKPES(0.64)GLT(0.057)LQES(0.002)NT(0.002)PGLR 69.071 0.00027072 353507200.0 267738.0 217255.0 235714.2 219629.0 228035.0 228360.0 208432.0 204363.0 241307.0 183226.1 True False 263920.00702286465 216751.95939560706 216334.68835912485 235781.2493208666 214622.42963405943 218593.57513316028 219223.58909439153 213858.451043811 214128.46458463924 214896.48725156803 1.2281262034493257 1.0086342600001037 1.0066925296264764 1.0971852185040598 0.9987246994075442 1.0172040405540193 1.0201357495330206 0.9951695989960884 0.996426080869206 1.0 17.71328237476341 -4.759999530858284 24.99999887105737 1.01736337505165 1.2281264602872193 0.8329434853153139 0.028546676194069306 14.378585109057655 249567.52368684713 0.007245341774285414 0.04417838043296443 1.737802705990135e-05 4.759999530858284 0.2107630852355693 ANSALTPPKPESGLT(ph)LQESNTPGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ANSALTPPKPESGLTLQESNTPGLR 25 1 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 ANS(0.032)ALT(0.148)PPKPES(0.261)GLT(0.341)LQES(0.109)NT(0.109)PGLR;ANS(0.001)ALT(0.016)PPKPES(0.411)GLT(0.552)LQES(0.016)NT(0.004)PGLR 70.345 0.00034266 507580000.0 146581.0 164929.0 192490.0 204758.0 201443.0 192972.0 198071.0 206604.0 204959.0 161371.0 True False 171394.26819328385 181302.06114221195 197079.6916223899 193286.07309439316 161971.6902206749 182852.20861220913 179308.28097014307 201180.8639150324 207956.13763066675 190626.28488786655 0.8991114121229625 0.9510863690642691 1.0338537087806094 1.0139528932649093 0.8496818280645435 0.9592182354063584 0.9406272648896181 1.0553679102195923 1.0909100901431 1.0 17.540387536301893 -7.765110974842803 24.909776234972913 1.0548542880041938 0.9519380019937015 0.4199022498473334 0.05319205128867664 91.11087628581865 618116.9098813512 0.029064455121435 0.014816259894750997 1.717469467793846e-08 7.765110974842803 -0.1029162860104923 ANSALTPPKPESGLT(ph)LQESNTPGLR ddPTM_PC-9_Lapatinib_30min_R1 2 ANSALTPPKPESGLTLQESNTPGLR 25 1 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 ANS(0.001)ALT(0.014)PPKPES(0.156)GLT(0.696)LQES(0.059)NT(0.074)PGLR;ANS(0.001)ALT(0.007)PPKPES(0.039)GLT(0.799)LQES(0.135)NT(0.02)PGLR 57.802 0.0034463000000000002 406397000.0 138330.0 111806.0 149962.0 121831.0 131719.0 133262.0 101822.0 112186.0 135224.0 122265.0 True False 136357.3888333851 111547.12007634036 137632.70323005988 130790.85815630197 123971.5473895178 127562.6949088946 107093.84494112761 117398.57111512836 119993.64914815262 143398.34234212793 0.9508993382089166 0.7778829117159869 0.9597928468495678 0.9120806839193001 0.8645256658109717 0.8895688250324977 0.7468276354660852 0.8186884813147433 0.8367854689830719 1.0 17.12966882128964 -7.083277128708103 24.99999194534193 0.8329991239003387 0.8899757491450111 0.048347325168636046 0.07604025419626656 201.74181144765512 60560.39829185938 0.02759742974837905 0.021376883749366582 8.255110126325402e-08 7.083277128708103 0.056976625244672396 ANSALTPPKPESGLTLQES(ph)NTPGLR ddPTM_PC-9_AZD4547_30min_R2 1 ANSALTPPKPESGLTLQESNTPGLR 25 1 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 ANS(0.001)ALT(0.01)PPKPES(0.287)GLT(0.259)LQES(0.333)NT(0.11)PGLR 53.443999999999996 0.0048479 327350000.0 22901.0 23909.0 33808.0 40740.0 35084.0 33808.0 32431.0 34557.0 29615.0 32246.0 True False 30183.041629608542 31637.116684022185 33359.68383024522 31348.02242672554 30213.192193921957 31693.980415530703 35317.2961728282 29217.009690861032 31180.38843977923 31117.07735491851 0.9699831795044103 1.0167123449021949 1.072069958555161 1.0074218111544633 0.9709521189703351 1.0185397572539376 1.1349811478116143 0.9389381064813549 1.002034608974956 1.0 14.9254189423294 ANSFES(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ANSFESR 7 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 ANS(0.474)FES(0.526)R 76.1 0.031751 4179100.0 31934.0 31901.0 24424.0 37407.0 42580.0 38813.0 32556.0 39066.0 30724.0 33373.0 True False 37339.79547475 35067.92045363573 25006.360788535796 35311.20706513028 34236.75466308755 36777.57795361849 29472.059994971318 38040.55889384846 31173.280375902574 39423.26071947734 0.9471513718879679 0.8895235912414058 0.634304731069118 0.8956947350548436 0.8684404597251552 0.9328903110099229 0.7475804755137984 0.9649267513545436 0.79073318155292 1.0 15.266759486962554 -14.522877986823179 0.37468111492478395 3.0179591890289603 0.8478340384117258 0.16803346450710577 0.09721773572153034 1035.7536894294883 7.889457584997182 1695.0792349035194 0.06615295875151621 3.000005239241016e-15 14.522877986823179 -2.1701251506172348 ANSFVGT(ph)AQYVSPELLTEK ddPTM_PC-9_AZD4547_30min_R2 2 ANSFVGTAQYVSPELLTEK 19 0 E9PER6;Q6A1A2;O15530-4;O15530-5;O15530;O15530-2 E9PER6 PDPK1;PDPK2P Putative 3-phosphoinositide-dependent protein kinase 2;3-phosphoinositide-dependent protein kinase 1 1 ANS(0.21)FVGT(0.79)AQYVSPELLTEK;ANS(0.001)FVGT(0.996)AQY(0.001)VS(0.001)PELLTEK 197.94 1.5244e-14 318770000.0 170411.0 158977.0 212770.0 272748.0 254363.0 220944.0 214472.0 250986.0 194270.0 236124.0 True False 224598.15323100385 210363.20628532302 209948.53077855145 209870.16251459348 219049.08807497882 207128.33675251508 233559.59251268266 212201.88078451413 204538.71558993455 227857.37063055218 0.9856962388772895 0.9232231799356879 0.9214032892487024 0.9210593536378371 0.9613429992139464 0.9090262745476549 1.0250254001718297 0.9312925897340321 0.8976611773580655 1.0 17.79777151342087 ANSFVGT(ph)AQYVSPELLTEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ANSFVGTAQYVSPELLTEK 19 0 E9PER6;Q6A1A2;O15530-4;O15530-5;O15530;O15530-2 E9PER6 PDPK1;PDPK2P Putative 3-phosphoinositide-dependent protein kinase 2;3-phosphoinositide-dependent protein kinase 1 1 ANS(0.001)FVGT(0.999)AQYVSPELLTEK;ANS(0.008)FVGT(0.983)AQY(0.005)VS(0.005)PELLTEK 188.09 1.1787e-10 136622000.0 129659.0 125752.0 121682.0 158773.0 152668.0 129837.0 146031.0 150230.0 122599.0 103577.0 True False 151607.7078180185 138235.82749398483 124583.36036155495 149877.46355901152 122753.80133640778 123028.11915502461 132197.8865071154 146286.62168184228 124391.77844047923 122354.69018491931 1.239083745697758 1.1297959014490067 1.0182148324127778 1.2249425284187798 1.0032619195135493 1.0055039080977406 1.0804480507230225 1.1955947210585367 1.0166490410173994 1.0 16.90070987930187 -4.8479751249907554 3.211609811897635 1.0762263263868277 1.2511050565175426 0.3103426142380836 0.07725429240976348 0.3745831092034995 6.300311919344706 0.019484250256037703 0.15109439953596615 1.4191388031268496e-05 4.8479751249907554 0.17487873013071487 ANSFVGT(ph)AQYVSPELLTEK ddPTM_PC-9_Lapatinib_30min_R1 3 ANSFVGTAQYVSPELLTEK 19 0 E9PER6;Q6A1A2;O15530-4;O15530-5;O15530;O15530-2 E9PER6 PDPK1;PDPK2P Putative 3-phosphoinositide-dependent protein kinase 2;3-phosphoinositide-dependent protein kinase 1 1 ANS(0.023)FVGT(0.977)AQYVSPELLTEK;ANS(0.112)FVGT(0.888)AQYVSPELLTEK;ANS(0.004)FVGT(0.996)AQYVSPELLTEK 171.33 8.5524e-08 227412000.0 274898.0 232151.0 255760.0 225285.0 250853.0 238440.0 230764.0 203053.0 239462.0 177083.0 True False 270977.9041098806 231613.46862281507 234732.4000621501 241853.2104287293 236098.31973597343 228242.47703078762 242711.83078307635 212487.5836614206 212491.2679133504 207691.56060173418 1.3047131203828897 1.115179971452731 1.1301971027713975 1.1644826093463803 1.1367737767097412 1.0989492128111142 1.1686167222196209 1.023092045944434 1.0231097849990163 1.0 17.66408306892754 -1.5228787458890922 0.12190490185931827 0.9416987719282306 1.8569781520063415 0.6452072581269508 0.0506718714297885 63.29823140602182 0.5308978065746287 0.3420802384505423 9.855670704675854 0.029999999957948716 1.5228787458890922 0.9152793800781109 ANSPS(ph)LFGTEGKPK ddPTM_PC-9_AZD4547_30min_R2 1 ANSPSLFGTEGKPK 14 1 Q5JPT2;Q96B97-2;Q96B97;Q96B97-3 Q5JPT2 SH3KBP1 SH3 domain-containing kinase-binding protein 1 1 ANS(0.414)PS(0.584)LFGT(0.001)EGKPK 59.294 0.02837 206110000.0 477340.0 341300.0 468040.0 506460.0 455060.0 420640.0 464070.0 465140.0 397660.0 423480.0 True False 629124.1907112063 451618.55051473406 461833.48378809646 389703.47172899917 391882.7739073697 394337.31430397625 505371.3309772856 393263.300853867 418679.49576101964 408654.09409727925 1.5395029679096879 1.1051364883847883 1.1301330158169367 0.9536267404584746 0.9589596178475648 0.9649660189385135 1.2366726242977097 0.9623378464434312 1.0245327327158844 1.0 18.640520662650005 -4.059741527777912 1.3373148627694489 1.0229013350638796 3.704338504770164 0.761700216169041 0.0853139917582756 3.7659720886669037 1.4613579319459071 0.025078812403327367 21.979705983278144 8.714821019511992e-05 4.059741527777912 2.6814371697062844 ANSPS(ph)LFGTEGKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ANSPSLFGTEGKPK 14 1 Q5JPT2;Q96B97-2;Q96B97;Q96B97-3 Q5JPT2 SH3KBP1 SH3 domain-containing kinase-binding protein 1 1 ANS(0.037)PS(0.963)LFGTEGKPK;ANS(0.035)PS(0.964)LFGT(0.001)EGKPK 67.118 0.01654 286810000.0 282443.0 318850.0 327190.0 397731.0 428050.0 382430.0 396990.0 414660.0 337484.0 262751.0 True False 330255.0213964676 350503.32079376036 334991.45047498425 375447.4215313006 344176.6752826354 362374.69757046114 359384.2332412973 403775.61436858657 342419.06504299975 310385.6763642291 1.0640150192012157 1.1292509528772658 1.079274837676082 1.209615810655912 1.108867778030947 1.167498132694836 1.157863460231231 1.3008835301238801 1.103205112600558 1.0 18.24370245620444 -5.742955680909828 24.99077596148113 1.1616214390338258 1.0946873190914121 0.09951139656707808 0.07512385869090553 474.17096774147217 641094.9011467098 0.019426860319856167 0.03357031288376814 1.8073585547871893e-06 5.742955680909828 -0.0669341199424136 ANSPS(ph)LFGTEGKPK ddPTM_PC-9_Lapatinib_30min_R1 2 ANSPSLFGTEGKPK 14 1 Q5JPT2;Q96B97-2;Q96B97;Q96B97-3 Q5JPT2 SH3KBP1 SH3 domain-containing kinase-binding protein 1 1 ANS(0.035)PS(0.965)LFGTEGKPK;ANS(0.009)PS(0.991)LFGTEGKPK 84.734 0.0033832999999999997 299260000.0 1149810.0 985980.0 1177600.0 1051780.0 899160.0 929650.0 837500.0 731010.0 906490.0 713890.0 True False 1133413.498550673 983697.0238884327 1080782.2736674577 1129131.409835225 846273.1766165762 889891.0366199953 880861.6520810268 764975.3932832094 804391.5504371165 837284.93530137 1.3536771662357874 1.1748653085874088 1.2908177707490271 1.348562911177673 1.0107349851122915 1.062829389495334 1.0520452655271673 0.913638071139864 0.9607142282424872 1.0 19.67535914236438 -6.271001235270558 24.51737080128771 1.0014199058753472 1.2835323244336656 0.8473904692558745 0.060659970468470895 205.1108328035719 525919.7272242515 0.019802176511659216 0.022752851581234933 5.357951335407325e-07 6.271001235270558 0.28211241855831837 ANST(ph)SDSVFTETPSPVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ANSTSDSVFTETPSPVLK 18 0 C9JEZ4;Q9UKI2 C9JEZ4 CDC42EP3 Cdc42 effector protein 3 1 ANS(0.009)T(0.494)S(0.494)DS(0.003)VFTETPSPVLK;ANS(0.094)T(0.696)S(0.194)DS(0.015)VFTETPSPVLK 165.66 3.4034999999999995e-07 15208600.0 73524.0 75082.0 61745.0 83539.0 100758.0 96784.0 99443.0 137820.0 99411.0 85313.0 True False 85970.16103480678 82535.64476034846 63217.2349692165 78858.58066709233 81015.19319735486 91708.47666150542 90023.03913502695 134202.3710323607 100864.69780786544 100779.57156266352 0.8530514637220061 0.8189719749803539 0.627282235764505 0.7824857701251391 0.8038850725514406 0.9099907376018384 0.8932667378830015 1.3316426032721849 1.0008446775857642 1.0 16.620843702638872 -7.309116608144426 1.7734414161379393 1.1171425989231365 0.7754649397041289 0.5837717738084112 0.11409927827811245 0.23594076635650593 1.4454129566053089 0.06157648894489114 0.03665568200206835 4.907760849956757e-08 7.309116608144426 -0.3416776592190076 ANST(ph)SDSVFTETPSPVLK ddPTM_PC-9_Lapatinib_30min_R1 2 ANSTSDSVFTETPSPVLK 18 0 C9JEZ4;Q9UKI2 C9JEZ4 CDC42EP3 Cdc42 effector protein 3 1 ANS(0.049)T(0.742)S(0.207)DS(0.002)VFTETPSPVLK;ANS(0.244)T(0.754)S(0.002)DSVFTETPSPVLK 292.65 2.0636999999999994e-120 19769000.0 90826.0 78403.0 86993.0 76990.0 115209.0 106030.0 118598.0 95018.0 119636.0 108379.0 True False 89530.80458455168 78221.46267056584 79840.7713426909 82652.10143111112 108432.63312960882 101495.3440680022 124738.42413552928 99432.883160263 106161.3338570695 127112.16574406016 0.7043448914624081 0.6153735341750407 0.6281127449551129 0.6502296687913477 0.8530468542872403 0.7984707323165485 0.9813256143136574 0.7822452129442174 0.8351783893826884 1.0 16.955742589899145 -6.273310314302715 4.2914536762368485 0.867677937204119 0.6435583399101158 0.7159034931010417 0.06952847516605548 0.11376956535179578 5.275587541350747 0.021039884849721222 0.025458207078348696 5.329539504383212e-07 6.273310314302715 -0.22411959729400321 ANSTS(ph)DSVFTETPSPVLK ddPTM_PC-9_Lapatinib_30min_R1 2 ANSTSDSVFTETPSPVLK 18 0 C9JEZ4;Q9UKI2 C9JEZ4 CDC42EP3 Cdc42 effector protein 3 1 ANS(0.189)T(0.005)S(0.806)DSVFTETPSPVLK;ANS(0.004)T(0.2)S(0.464)DS(0.332)VFTETPSPVLK 223.65 8.499700000000001e-35 13651800.0 91622.0 77802.0 89060.0 74777.0 106581.0 108437.0 110451.0 89177.0 115192.0 106657.0 True False 90315.45347858281 77621.85424914071 81737.83058154165 80276.35002875954 100312.11512630833 103799.4022889932 116169.61233910639 93320.48897664416 102217.86393446414 125092.520338481 0.7219892383189912 0.6205155515222492 0.6534190082698129 0.641735811314251 0.8019033820317896 0.8297810453265158 0.9286695321572337 0.7460117417422989 0.8171380963296481 1.0 16.932636003403502 -6.38890513238829 3.0290652692454376 0.8510504883960335 0.65526009857982 0.6629632255693059 0.06863853953037288 0.16795995175779538 2.9414237984271105 0.022213127642309493 0.025562319391516264 4.084085896675495e-07 6.38890513238829 -0.19579038981621344 ANSTSDSVFTETPS(ph)PVLK ddPTM_PC-9_AZD4547_30min_R2 2 ANSTSDSVFTETPSPVLK 18 0 C9JEZ4;Q9UKI2 C9JEZ4 CDC42EP3 Cdc42 effector protein 3 1 ANSTSDSVFTET(0.023)PS(0.977)PVLK;ANSTSDSVFTET(0.032)PS(0.968)PVLK 149.12 3.9891e-05 15253600.0 86235.0 78652.0 119234.0 150162.0 139454.0 123180.0 93600.0 99308.0 92815.0 118142.0 True False 113655.93620057176 104074.7208763107 117652.87925388831 115544.47087977329 120093.21925125962 115477.5351273391 101930.21867277376 83962.23047081709 97721.01141442191 114005.8845396259 0.9969304361747002 0.9128890258303873 1.031989530443885 1.0134956747746877 1.053394916729214 1.012908549358272 0.894078573964707 0.7364727777857264 0.8571576090921541 1.0 16.798748767046412 -7.385667437619452 4.171281278496605 0.8426962745256538 1.0032048314786364 0.45420833880963896 0.06962314214159694 0.18481512805046016 5.37763738641864 0.030296952910658922 0.019718790127586303 4.1146468088622596e-08 7.385667437619452 0.1605085569529826 ANSTSDSVFTETPS(ph)PVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ANSTSDSVFTETPSPVLK 18 0 C9JEZ4;Q9UKI2 C9JEZ4 CDC42EP3 Cdc42 effector protein 3 1 ANSTSDSVFTET(0.036)PS(0.964)PVLK;ANSTSDSVFTET(0.203)PS(0.797)PVLK 160.02 1.2804000000000002e-17 4072500.0 30627.0 38155.0 44353.0 57231.0 68411.0 79108.0 77377.0 75560.0 70510.0 59569.0 True False 35811.54618917669 41942.77624238963 45410.54372968916 54024.53261540547 55006.3556424726 74959.43721832505 70047.29039903234 73576.63006243772 71541.07535818551 70368.38815205554 0.5089152548413259 0.5960457151833232 0.6453259044610171 0.7677386683728857 0.7816912833588302 1.065243061363704 0.9954369033957498 1.0455920903495706 1.0166649718279175 1.0 16.102639846783305 -6.16570162485335 0.9016983092766516 1.0392164939790847 0.5326227349344447 0.9372023485736548 0.04946135411359725 0.13532633975460526 0.2312596497082886 0.023417935942035218 0.042826406741159805 6.828076452107646e-07 6.16570162485335 -0.50659375904464 ANSTSDSVFTETPS(ph)PVLK ddPTM_PC-9_Lapatinib_30min_R1 2 ANSTSDSVFTETPSPVLK 18 0 C9JEZ4;Q9UKI2 C9JEZ4 CDC42EP3 Cdc42 effector protein 3 1 ANSTSDSVFTET(0.003)PS(0.997)PVLK;ANSTSDSVFTET(0.032)PS(0.968)PVLK 217.67 1.2937999999999998e-27 8996700.0 82359.0 73387.0 88978.0 77146.0 94906.0 126326.0 98597.0 117498.0 131046.0 95731.0 True False 81184.54555720919 73217.07691038381 81662.5723050124 82819.57419151173 89323.815672375 120923.33146028902 103701.87022117384 122957.38602753768 116286.21950444298 112277.97579646079 0.7230674135449482 0.6521054230895009 0.727324942632129 0.7376297408643019 0.7955595479767338 1.0769995682813223 0.9236172052938162 1.0951158065980517 1.0356992872337527 1.0 16.77671543400612 -6.625497062570434 3.5929663775402227 1.026107273643044 0.7112606530488952 0.9020454207645627 0.04976168163151237 0.06838461202386907 1.7124979447182678 0.01734515037527932 0.017344541057237164 2.3686611525996475e-07 6.625497062570434 -0.3148466205941489 ANSWQLVET(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 1 ANSWQLVETPEK 12 0 Q9Y2H0-3;Q9Y2H0;F8WF49;A0A0B4J2C2;Q9Y2H0-1 Q9Y2H0-3 DLGAP4 Disks large-associated protein 4 1 ANSWQLVET(1)PEK 124.09 0.0012431 0.0 12309.0 11345.0 11282.0 13186.0 15607.0 14300.0 13096.0 14467.0 11511.0 12007.0 True False 16223.005956894975 15012.04938643321 11132.393308472156 10146.17142166919 13440.237446429723 13405.818739413424 14261.518629686349 12231.457568587744 12119.447959827743 11586.638584646358 1.4001477510822113 1.2956345601670807 0.9607957672231073 0.8756785971657083 1.1599772745341 1.157006723000551 1.2308590214063049 1.0556519459229396 1.0459848101145934 1.0 13.500174464389076 -5.09331867579616 4.752312903094643 1.0699646246078838 1.378638884831713 0.5804302923379471 0.0990033268845571 0.16005345250206998 5.873686936907681 0.02827591555779031 0.08396495035060567 8.066429160984031e-06 5.09331867579616 0.30867426022382927 ANSWQLVET(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ANSWQLVETPEK 12 0 Q9Y2H0-3;Q9Y2H0;F8WF49;A0A0B4J2C2;Q9Y2H0-1 Q9Y2H0-3 DLGAP4 Disks large-associated protein 4 1 ANSWQLVET(1)PEK;ANSWQLVET(1)PEK 107.35 0.001685 0.0 16418.800000000003 23485.0 20520.8 21469.0 26615.0 16477.7 24015.0 23941.0 19168.9 17561.300000000003 True False 19198.178553918253 25816.43559304209 21010.093697567376 20266.16153343711 21399.981807376127 15613.580404666973 21740.125346456465 23312.574117586297 19449.208898504057 20745.02467482569 0.9254353202681628 1.244463961731056 1.012777474449734 0.97691672346046 1.0315717692707898 0.7526421708051386 1.047968160425393 1.1237669987385628 0.9375360696536496 1.0 14.340477752749733 -5.504500441352714 24.21224385834383 0.9829557113658556 1.0958674176777756 0.11014601611112673 0.1153170581373529 964.8042317808587 1271063.9429419176 0.030123930093414485 0.060827762263632866 3.1296772910206856e-06 5.504500441352714 0.11291170631192005 ANSWQLVET(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 3 ANSWQLVETPEK 12 0 Q9Y2H0-3;Q9Y2H0;F8WF49;A0A0B4J2C2;Q9Y2H0-1 Q9Y2H0-3 DLGAP4 Disks large-associated protein 4 1 ANSWQLVET(1)PEK;ANSWQLVET(1)PEK;ANSWQLVET(1)PEK 139.64 0.00017853 2271700.0 41018.0 48871.0 40295.0 40904.0 51664.0 45449.0 43101.0 42658.0 46164.0 36256.7 True False 40433.075798220045 48757.84220212528 36982.10064319814 43912.21661174396 48625.225095332054 43505.25221679365 45332.55888518734 44640.0464106853 40964.524191528966 42523.622285984 0.9508379960271398 1.1466060410896866 0.8696836876802855 1.032654657602338 1.1434873719908658 1.0230843441371926 1.0660559107667829 1.0497705513059947 0.9633357176401945 1.0 15.375976874617967 ANSWQLVET(ph)PEKR ddPTM_PC-9_AZD4547_30min_R2 2 ANSWQLVETPEKR 13 1 Q9Y2H0-3;Q9Y2H0;F8WF49;A0A0B4J2C2;Q9Y2H0-1 Q9Y2H0-3 DLGAP4 Disks large-associated protein 4 1 ANSWQLVET(1)PEKR;ANSWQLVET(1)PEKR 87.15700000000001 0.0061448 38035700.0 34298.0 32403.0 33153.0 48141.0 50469.0 41220.0 37415.0 40004.0 33827.0 37259.0 True False 45204.05055728196 42876.63607479906 32713.369558214632 37042.836221035715 43462.25050835276 38642.50688381968 40744.862517540845 33822.30100046896 35615.02616081078 35954.57375075698 1.2572545254087526 1.1925224415682678 0.9098527988396996 1.030267706073301 1.2088100615415505 1.074759143348379 1.1332316939700338 0.9406953684093354 0.9905562059419757 1.0 15.1338876858975 -5.062083925984195 7.563984923091354 1.044761616878976 1.2418476293318965 0.45413978737320326 0.08371164103229571 0.23323397818658945 25.58071888329446 0.022698547545920576 0.061711146148077774 8.667943544062518e-06 5.062083925984195 0.19708601245292057 ANSWQLVET(ph)PEKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ANSWQLVETPEKR 13 1 Q9Y2H0-3;Q9Y2H0;F8WF49;A0A0B4J2C2;Q9Y2H0-1 Q9Y2H0-3 DLGAP4 Disks large-associated protein 4 1 ANSWQLVET(1)PEKR;ANSWQLVET(1)PEKR 85.176 0.0069795000000000005 32799000.0 64117.0 70696.0 66856.0 76410.0 87177.0 77333.0 76696.0 70945.0 65114.0 64752.0 True False 74970.74173152572 77714.23166641283 68450.10059279205 72128.99542456226 70095.29265533082 73277.52134303394 69430.79964904526 69082.76892244109 66066.16906641454 76491.02502345016 0.9801246840206631 1.0159915054424709 0.8948775437615986 0.9429733148751686 0.9163858457098911 0.9579884871534792 0.9076986434390124 0.90314868837569 0.8637113837363322 1.0 16.223002860508224 -5.2577216056579505 24.988667501003732 0.9210195245842192 0.9980580994890971 0.4020822828020094 0.03635342460345051 284.2207934392236 1910343.0754555515 0.008980749924645213 0.021858291051857905 5.524314490915536e-06 5.2577216056579505 0.07703857490487787 ANSWQLVET(ph)PEKR ddPTM_PC-9_Lapatinib_30min_R1 1 ANSWQLVETPEKR 13 1 Q9Y2H0-3;Q9Y2H0;F8WF49;A0A0B4J2C2;Q9Y2H0-1 Q9Y2H0-3 DLGAP4 Disks large-associated protein 4 1 ANSWQLVET(1)PEKR 86.005 0.0066302999999999996 37120000.0 30032.0 33755.0 35182.0 34912.0 37070.0 33638.0 31917.0 32898.0 36445.0 24440.0 True False 29603.7381728057 33676.84237140103 32289.47176644734 37479.5449430179 34889.61548242414 32199.381154007868 33569.506088919596 34426.56118005356 32340.180317136146 28664.421435747026 1.032769429488197 1.1748655889284085 1.1264651490987208 1.3075283946348084 1.2171749414385094 1.1233222071544218 1.171121006721437 1.201020619140097 1.1282341905846085 1.0 14.806973539444085 -8.623837514878751 4.541007308982254 1.0000136357492844 1.1725361317803944 0.3639166412342224 0.06717748181090145 0.7162393259911903 30.40487946054845 0.06612696337541187 0.017242634088782686 2.3777297140827778e-09 8.623837514878751 0.17252249603111003 ANT(ph)LSHFPIECQEPPQPAR ddPTM_PC-9_AZD4547_30min_R2 2 ANTLSHFPIECQEPPQPAR 19 0 C9JIE2;Q86TI0-2;Q86TI0;H7C380;H7C0Z7;H0Y8P0;H0YA01 C9JIE2 TBC1D1 TBC1 domain family member 1 1 ANT(0.983)LS(0.017)HFPIECQEPPQPAR;ANT(0.914)LS(0.086)HFPIECQEPPQPAR 141.18 9.349899999999999e-10 12933000.0 1847.2 5130.6 5067.1 5167.1 5018.799999999999 4128.5 4728.8 7090.5 3492.0 4543.9 True False 2434.5711758531465 6788.966115648672 4999.906943215673 3975.904925899205 4322.026250793968 3870.3442423544257 5149.654039100555 5994.826148480776 3676.5799909407087 4384.819444055522 0.5552272349899567 1.5482886358872632 1.140276585389171 0.9067431342673231 0.9856794118748305 0.8826690110584673 1.1744278424239145 1.3671774231451954 0.8384792208320072 1.0 12.098301721966363 -10.260151593061405 15.220030142294835 1.0000475622659728 1.064769633636781 0.0 0.26799186607862185 0.0 0.0 0.24993097130688482 0.06061716434185312 5.4934908683460386e-11 10.260151593061405 0.0647220713708081 ANT(ph)LSHFPIECQEPPQPAR ddPTM_PC-9_Lapatinib_30min_R1 1 ANTLSHFPIECQEPPQPAR 19 0 C9JIE2;Q86TI0-2;Q86TI0;H7C380;H7C0Z7;H0Y8P0;H0YA01 C9JIE2 TBC1D1 TBC1 domain family member 1 1 ANT(0.655)LS(0.345)HFPIECQEPPQPAR 85.49600000000001 0.0031574000000000003 4435600.0 0.0 857.42 2141.5 2064.4 1772.5 2056.3 1746.0 2209.8 1790.1 1942.4 True False 0.0 855.4346966697274 1965.434136429055 2216.222862636521 1668.2450348690784 1968.356842469421 1836.3993367563887 2312.4753752715196 1588.4800874113166 2278.1412519146897 0.0 0.3754967765720267 0.8627358530895235 0.9728206540195307 0.7322834058103214 0.8640187876037507 0.8060954671765703 1.0150711126133962 0.6972702355818633 1.0 11.153641486106313 -5.048277511864343 2.456367613112989 0.8685069564527419 6.693254623491996e-18 0.8834910070275374 0.10319814314479439 0.09938220727453476 1.0506607837212918 0.026547096221851772 0.14193812426015526 8.947928149821363e-06 5.048277511864343 -0.8685069564527419 down ANTIPIIGS(ph)PSSKR ddPTM_PC-9_AZD4547_30min_R2 1 ANTIPIIGSPSSKR 14 1 E9PGM7;O94988-6;O94988-5;O94988-1;O94988 E9PGM7 FAM13A Protein FAM13A 1 ANTIPIIGS(0.49)PS(0.255)S(0.255)KR 60.618 0.025275 6449400.0 55720.0 43272.0 55084.0 70849.0 76226.0 70177.0 63818.0 71055.0 62976.0 60635.0 True False 73437.8009520016 57258.827769919604 54353.550168753805 54515.857656138396 65643.3356565358 65788.82109621084 69497.67836815237 60075.082431464834 66304.78279194787 58512.187105857585 1.2550855571189174 0.9785795165429304 0.9289269955064205 0.9317009045912228 1.1218745855077483 1.1243609981146099 1.1877470627173845 1.0267105948847841 1.1331790191330957 1.0 15.836449524690105 -6.292942680581109 24.715641760862876 1.1060217826648113 1.0135989323722894 0.11573051385972188 0.09947554382570435 1095.490354258292 859454.5979310469 0.031319728858911065 0.035516790163182224 5.093980984281233e-07 6.292942680581109 -0.09242285029252195 ANTLS(ph)HFPIECQEPPQPAR ddPTM_PC-9_AZD4547_30min_R2 1 ANTLSHFPIECQEPPQPAR 19 0 C9JIE2;Q86TI0-2;Q86TI0;H7C380;H7C0Z7;H0Y8P0;H0YA01 C9JIE2 TBC1D1 TBC1 domain family member 1 1 ANT(0.035)LS(0.965)HFPIECQEPPQPAR 118.5 5.563e-05 4713200.0 1597.3 2383.8 5458.6 6346.7 4649.9 4808.5 3521.0 5868.8 4808.6 5031.5 True False 2105.2081740960552 3154.316732250284 5386.215397414118 4883.566370537529 4004.3416481164563 4507.823734858005 3834.362178919188 4961.9118116076415 5062.772779048537 4855.34871646941 0.4335853709034657 0.6496581227113097 1.1093364682837303 1.0058116637374377 0.8247279200634291 0.92842430031182 0.7897192154114449 1.021947567798121 1.042720734326567 1.0 12.245359199967599 -5.043816392097015 4.077414471820361 0.9539812949077047 0.465131371253638 0.7753133919547031 0.09424855907853917 0.09542327663341713 3.352605245193872 0.025784029726539138 0.0898984571476117 9.040315929280478e-06 5.043816392097015 -0.48884992365406665 ANTLS(ph)HFPIECQEPPQPAR ddPTM_PC-9_Lapatinib_30min_R1 1 ANTLSHFPIECQEPPQPAR 19 0 C9JIE2;Q86TI0-2;Q86TI0;H7C380;H7C0Z7;H0Y8P0;H0YA01 C9JIE2 TBC1D1 TBC1 domain family member 1 1 ANT(0.002)LS(0.998)HFPIECQEPPQPAR 115.53 7.3156e-05 4053400.0 3235.6 2685.7 4238.5 5150.8 8574.7 8308.9 7612.9 10016.0 10145.0 7961.1 True False 3189.459750663632 2679.4814266589165 3890.026891083143 5529.607014565095 8070.3530045088255 7953.54771599192 8007.058711794212 10481.379925205685 9002.363268413943 9337.165527501047 0.34158757722240396 0.28696946827888564 0.4166175355492761 0.5922147356474049 0.8643257935975281 0.8518160776486275 0.8575470455365465 1.122544084105026 0.9641430519678589 1.0 13.188768943800035 -6.088369112463162 0.9016755617305249 1.0004855849786851 0.2612156731489207 0.9438074638806234 0.06685042866672443 0.13620769465919 0.22890894727372293 0.03227383798979167 0.06517823332925976 8.158886423501127e-07 6.088369112463162 -0.7392699118297644 down ANTLS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 1 ANTLSPVR 8 0 Q9H792;H0YN99;H3BUZ5 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 ANT(0.168)LS(0.832)PVR 75.566 0.026189999999999998 46515000.0 66370.0 61741.0 77049.0 99754.0 97286.0 76495.0 67230.0 106880.0 82645.0 89294.0 True False 87474.27941824008 81697.57083893982 76027.27991707782 76757.25648393671 83779.51817859673 71711.75555744254 73213.33975823272 90364.15185806713 87013.44597688856 86167.84423897811 1.015161516349866 0.9481213271665423 0.8823161422748789 0.890787708127616 0.9722828616466533 0.8322333718661566 0.8496596428150466 1.0486992294648914 1.0098134257086118 1.0 16.394861970303744 -7.77284374573637 24.99985599236879 1.0219422727468632 0.9114395790320898 0.45509038091066156 0.05339970145725261 211.24979772808652 463079.7291634336 0.030386890984279494 0.014798491443401868 1.6871599373470662e-08 7.77284374573637 -0.11050269371477339 ANTTAFLT(ph)PLEIK ddPTM_PC-9_AZD4547_30min_R2 2 ANTTAFLTPLEIK 13 0 Q9Y5K6 Q9Y5K6 CD2AP CD2-associated protein 1 ANTTAFLT(1)PLEIK;ANT(0.002)T(0.018)AFLT(0.981)PLEIK 133.87 0.00010779 6678800.0 40355.0 39138.0 48305.0 66770.0 58546.0 55614.0 52463.0 73234.0 49308.0 57185.0 True False 53187.05056385545 51788.59311469574 47664.44413807366 51377.2080862166 50417.89847752125 52136.44778837327 57132.10536570214 61917.368049903525 51914.32021572288 55182.97055575934 0.9638308707957808 0.9384886785383586 0.8637527784031013 0.9310337513328096 0.9136495909834493 0.9447923383481552 1.0353213100040222 1.1220376037447901 0.9407670462985738 1.0 15.751935500081 -7.187407383377711 3.8836826290790296 1.0351016637285146 0.9212266047619182 0.49882253879894956 0.048311794484224804 0.1783465918465349 5.19949107866635 0.01925091559188797 0.014349192298809176 6.495201319470188e-08 7.187407383377711 -0.11387505896659644 ANTTAFLT(ph)PLEIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ANTTAFLTPLEIK 13 0 Q9Y5K6 Q9Y5K6 CD2AP CD2-associated protein 1 ANT(0.001)T(0.001)AFLT(0.998)PLEIK;ANT(0.003)T(0.003)AFLT(0.995)PLEIK 87.824 0.016888999999999998 1810300.0 17013.2 16297.3 20830.7 20540.1 24551.5 17213.8 20131.7 15423.7 18066.4 11471.2 True False 19893.198733983107 17915.18823889652 21327.382888869663 19389.30478890268 19740.809819417427 16311.078024836994 18224.679635113785 15018.844217760987 18330.586921729147 13550.837754030772 1.4680419834608207 1.3220723739805347 1.573879288941063 1.43085653749601 1.456796264389293 1.203695175228939 1.3449116553471208 1.1083332625168174 1.352727208048566 1.0 13.726094425683911 -8.034519650652227 0.3424201606865529 0.9876312507035093 1.4953745796550586 0.6091053255298262 0.1045107751305633 0.871437861406884 0.3325232243943615 0.16246852316955496 0.13328189014956587 9.23592397412919e-09 8.034519650652227 0.5077433289515493 ANVS(ph)SPHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ANVSSPHR 8 0 Q5QPM7;H0Y555;Q5QPM9;Q92530 Q5QPM7 PSMF1 Proteasome inhibitor PI31 subunit 1 ANVS(0.5)S(0.5)PHR;ANVS(0.5)S(0.5)PHR;ANVS(0.5)S(0.5)PHR 99.973 0.0050353 37269700.0 47110.0 94722.0 84149.0 51352.0 95401.0 69157.0 64089.0 59808.0 77718.0 73855.0 True False 55084.79253508714 104125.37416411012 86155.43129685974 48474.91392543026 76707.85889180868 65530.28517605942 58018.025955821235 58238.10337181411 78854.47872198923 87244.32686414185 0.6313853807464866 1.1934916332870065 0.987519010044312 0.5556225334962593 0.8792303367903712 0.7511122789462763 0.6650062879866991 0.667528829267069 0.9038350292367157 1.0 16.412773701461212 -5.713321032043082 24.999969949334613 0.7595779390723001 0.9630685007935936 0.14173564166463248 0.1776857901120194 175.9643553740854 91421.09876362023 0.04573711089752374 0.07921879205389805 1.9349910827873922e-06 5.713321032043082 0.20349056172129354 ANVS(ph)SPHREFPPATAR ddPTM_PC-9_AZD4547_30min_R2 6 ANVSSPHREFPPATAR 16 1 Q5QPM7;H0Y555;Q5QPM9;Q92530 Q5QPM7 PSMF1 Proteasome inhibitor PI31 subunit 1 ANVS(0.5)S(0.5)PHREFPPATAR;ANVS(0.5)S(0.5)PHREFPPATAR;ANVS(0.683)S(0.317)PHREFPPATAR;ANVS(0.5)S(0.5)PHREFPPATAR;ANVS(0.867)S(0.133)PHREFPPATAR;ANVS(0.839)S(0.161)PHREFPPATAR 90.581 0.0016404 172601000.0 150289.69999999998 133448.0 245540.0 331149.0 252046.0 230291.0 215253.0 233354.7 219909.0 227257.0 True False 198078.6983800436 176582.4562821278 242283.97916701407 254807.71425104918 217053.7635306486 215890.86736491325 234410.0999996852 197295.09307254627 231532.94078687843 219300.8016016478 0.9032283372125862 0.8052066157190051 1.1048020681981565 1.1619096345753375 0.9897536258208446 0.9844508811101905 1.0688975976726383 0.899655138657112 1.0557779045762445 1.0 17.742551559884745 -5.256796900878512 24.997547018981038 1.0321574088886218 0.8542174671055864 0.4986982101583398 0.07175635261972343 325.08576940970255 1750417.35487835 0.019262147164323003 0.04754581042275733 5.5360894557772465e-06 5.256796900878512 -0.1779399417830354 ANVS(ph)SPHREFPPATAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ANVSSPHREFPPATAR 16 1 Q5QPM7;H0Y555;Q5QPM9;Q92530 Q5QPM7 PSMF1 Proteasome inhibitor PI31 subunit 1 ANVS(0.5)S(0.5)PHREFPPATAR;ANVS(0.808)S(0.192)PHREFPPATAR 61.265 0.017766 24407600.0 41543.8 39380.3 45406.7 57642.0 58931.0 67182.3 68230.3 69250.7 65483.6 47805.0 True False 48576.34481254837 43289.71592866404 46489.367933868714 54412.505617885436 47383.89358972316 63659.14192032003 61767.03203940572 67432.94250218176 66441.17376720007 56471.668075828245 0.860189657357415 0.7665740610058848 0.8232334818132938 0.9635363620713694 0.8390737374022256 1.127275748873589 1.0937702770965971 1.1941021896437536 1.1765399541232802 1.0 15.78523962622517 -6.7630891063768175 24.998566344331365 1.128933604631254 0.8506202960917818 0.7982956039627908 0.06720501291257161 19.07983749680113 289115.9564721003 0.023654520808094555 0.021959648709794412 1.7254838294985428e-07 6.7630891063768175 -0.2783133085394721 ANVS(ph)SPHREFPPATAR ddPTM_PC-9_Lapatinib_30min_R1 4 ANVSSPHREFPPATAR 16 1 Q5QPM7;H0Y555;Q5QPM9;Q92530 Q5QPM7 PSMF1 Proteasome inhibitor PI31 subunit 1 ANVS(0.571)S(0.428)PHREFPPAT(0.001)AR;ANVS(0.5)S(0.5)PHREFPPATAR;ANVS(0.846)S(0.154)PHREFPPATAR;ANVS(0.787)S(0.212)PHREFPPAT(0.001)AR 127.88 0.00022534 90445000.0 89676.9 77866.2 99581.4 82313.9 102369.5 86272.1 83863.7 76126.1 91766.0 72488.7 True False 88398.09096127057 77685.90559798507 91394.20168732009 88367.53879712061 96348.3272761806 82582.44339308761 88205.75203776447 79663.19651799135 81430.34674118036 85018.27520987869 1.0397539910454354 0.9137553709035767 1.074994775672661 1.039394631083421 1.1332660776560357 0.9713493150645799 1.0374916665860026 0.9370126166560351 0.9577981503407231 1.0 16.37548537045555 -7.753503798332868 24.906459237944272 0.9605540353398537 1.0293376093027073 0.21624000936334775 0.0565698812255518 248.70693934316952 780593.7041859633 0.02769350717903837 0.015614793107950834 1.7639903365765605e-08 7.753503798332868 0.06878357396285362 ANVSS(ph)PHR ddPTM_PC-9_AZD4547_30min_R2 2 ANVSSPHR 8 0 Q5QPM7;H0Y555;Q5QPM9;Q92530 Q5QPM7 PSMF1 Proteasome inhibitor PI31 subunit 1 ANVS(0.076)S(0.924)PHR;ANVS(0.162)S(0.838)PHR 77.192 0.013538999999999999 49793000.0 50450.4 53329.0 53747.7 53785.1 52142.3 70262.0 61768.0 62176.0 75823.0 65438.1 True False 66492.57776649068 70566.55634456562 53034.97037987671 41385.77616651146 44903.24168661323 65868.50603277374 67265.2323395286 52568.127862342684 79830.84898427763 63147.13203680749 1.0529785854365197 1.1174942403311914 0.8398634849950658 0.6553864733300687 0.7110891696623661 1.043095765527087 1.0652143679355182 0.8324705519753698 1.264203874496556 1.0 15.946429591943389 -8.25307994949837 24.989536202499988 1.132101944242874 0.9128307127385388 0.22840008465653006 0.1598059377202071 892.9808681420444 2669481.373226873 0.12247056176204035 0.044614342120346005 5.583673951290321e-09 8.25307994949837 -0.21927123150433514 ANVSS(ph)PHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ANVSSPHR 8 0 Q5QPM7;H0Y555;Q5QPM9;Q92530 Q5QPM7 PSMF1 Proteasome inhibitor PI31 subunit 1 ANVS(0.228)S(0.772)PHR 77.533 0.023407 26320000.0 7939.8 16347.0 14809.0 8740.6 17139.0 14660.0 10473.0 10089.0 14711.0 11477.0 True False 9283.851321801845 17969.822126440667 15162.102723445243 8250.892519407544 13780.735983340945 13891.203792544953 9480.921622046151 9824.174440179118 14926.120544522286 13557.689248117995 0.6847664931611099 1.3254339878703991 1.1183397440349183 0.6085766068545115 1.0164516778000285 1.024599659892135 0.6993021781615361 0.7246201222337986 1.1009339623707814 1.0 13.726823688233072 ANVSS(ph)PHR ddPTM_PC-9_Lapatinib_30min_R1 5 ANVSSPHR 8 0 Q5QPM7;H0Y555;Q5QPM9;Q92530 Q5QPM7 PSMF1 Proteasome inhibitor PI31 subunit 1 ANVS(0.059)S(0.941)PHR;ANVS(0.153)S(0.847)PHR;ANVS(0.034)S(0.966)PHR;ANVS(0.429)S(0.571)PHR;ANVS(0.18)S(0.82)PHR 95.48299999999999 0.0036343000000000005 126402500.0 28950.8 76663.1 67549.5 60392.1 112411.0 81085.9 116236.0 123429.0 100900.0 90745.0 True False 28537.956283073512 76485.59130211684 61995.840858610485 64833.536496139764 105799.20598852918 77618.04507746497 122254.13133288414 129163.96193971748 89535.57947589627 106430.15233988802 0.2681378881422311 0.7186458876602724 0.5825026037792826 0.6091651197594065 0.9940717330804536 0.7292862348781509 1.148679473298711 1.213603091793276 0.8412614048503999 1.0 16.69954740787594 -5.9836767469162835 0.6385486938722709 1.0653206996133697 0.3785662119680862 0.6549612285709661 0.16077177991045194 0.6667612142596959 0.5123757353769999 0.09918116807183738 0.27587547871603835 1.0383009540864833e-06 5.9836767469162835 -0.6867544876452836 ANVSS(ph)PHREFPPATAR ddPTM_PC-9_AZD4547_30min_R2 2 ANVSSPHREFPPATAR 16 1 Q5QPM7;H0Y555;Q5QPM9;Q92530 Q5QPM7 PSMF1 Proteasome inhibitor PI31 subunit 1 ANVS(0.164)S(0.836)PHREFPPATAR;ANVS(0.282)S(0.718)PHREFPPATAR 65.225 0.012149 26105000.0 85357.0 58308.0 127930.0 185611.0 158638.0 126021.0 83628.0 147678.0 102401.0 127993.0 True False 112498.75046410655 77154.92072491383 126233.56461202294 142821.25161136364 136613.85199120356 118140.8869482252 91070.72999109743 124857.75840284122 107813.70780421517 123512.00402803728 0.9108325247363753 0.6246754826146261 1.0220347860550287 1.1563349873178574 1.106077527170494 0.9565134002797588 0.7373431490142799 1.0108957375066028 0.8729006435661218 1.0 16.914291737381376 -5.280027407412773 24.796753046522337 0.9840523480456662 0.7677539872316408 0.31354018026318253 0.1272440512862918 801.8242257930189 1069646.778211015 0.035498495894467214 0.07411311903593785 5.24774341798034e-06 5.280027407412773 -0.21629836081402543 ANVSS(ph)PHREFPPATAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ANVSSPHREFPPATAR 16 1 Q5QPM7;H0Y555;Q5QPM9;Q92530 Q5QPM7 PSMF1 Proteasome inhibitor PI31 subunit 1 ANVS(0.274)S(0.726)PHREFPPATAR 66.702 0.01239 33289000.0 92623.0 101870.0 119300.0 117760.0 97867.0 94907.0 120880.0 100650.0 89877.0 70257.0 True False 108302.24451236217 111982.98036462392 122144.56444776934 111162.2889830712 78690.66389413795 89929.90984577511 109429.37130458698 98008.04414748987 91191.28109442098 82994.0379458941 1.3049400558503628 1.3492894566429992 1.4717269754653757 1.3394008983577914 0.9481483952550709 1.0835707247357054 1.3185208722574353 1.1809046357207462 1.0987690604217963 1.0 16.340720080649547 -6.101252790183141 7.644578886459824 1.1241167132429781 1.3780256348797972 0.6083840418079394 0.1023136476861461 0.21113239448880544 14.117064718169518 0.03200600550898037 0.04147765758001713 7.920401727382317e-07 6.101252790183141 0.2539089216368191 ANVVT(ph)TPSTNR ddPTM_PC-9_AZD4547_30min_R2 1 ANVVTTPSTNR 11 0 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;E9PDP5 Q8IWZ3-6 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 1 ANVVT(0.451)T(0.451)PS(0.078)T(0.021)NR 99.75200000000001 0.010836 3392400.0 12740.0 23362.0 34778.0 38393.0 30185.0 35427.0 38374.0 44753.0 37262.0 40051.0 True False 16791.05499153807 30913.309631190183 34316.82099645846 29542.087015937 25994.333781026544 33211.744089594366 41789.211659711706 37837.4521716325 39231.593248119316 38648.82668057563 0.4344518691424344 0.7998511801323788 0.8879136559585553 0.7643721570151688 0.6725775660892428 0.8593208886800731 1.0812543419517155 0.9790064905294806 1.0150785060659184 1.0 15.238136996343577 -7.02334283537191 4.047362573401353 1.0151477561081503 0.7304670746289144 0.6174351170800899 0.11327477821175487 0.1632779956275641 6.021837743536606 0.0449566806661695 0.03623691264247203 9.476700699746988e-08 7.02334283537191 -0.284680681479236 ANVVTT(ph)PSTNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ANVVTTPSTNR 11 0 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;E9PDP5 Q8IWZ3-6 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 1 ANVVT(0.088)T(0.911)PS(0.001)TNR;ANVVT(0.115)T(0.431)PS(0.402)T(0.053)NR 107.09 0.0057523 8342300.0 38239.0 64870.0 86942.0 69980.0 87197.0 58936.0 75146.0 57418.0 53557.0 46889.0 True False 44712.10744532361 71309.86488910536 89015.02700937094 66059.2474782212 70111.37379890197 55845.2924091016 68027.6268700737 55910.8383393998 54340.16980511047 55389.60452688022 0.8072292233757529 1.2874232538435826 1.607070997702692 1.1926289787132 1.265785780522722 1.008226956774899 1.2281659609441755 1.0094103183615732 0.9810535798055668 1.0 15.757327617470335 -7.375659691856439 0.9594498934384984 0.98823892168516 1.249092328042982 0.1732567506946473 0.19421791236165153 0.9807343362867925 1.71150340940814 0.15829026590998352 0.08302801958570886 4.210564341136883e-08 7.375659691856439 0.26085340635782195 ANVVTT(ph)PSTNRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ANVVTTPSTNRK 12 1 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;E9PDP5 Q8IWZ3-6 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 1 ANVVT(0.02)T(0.975)PS(0.002)T(0.002)NRK 82.48299999999999 0.010241 9935800.0 28344.0 30051.0 49894.0 50056.0 55816.0 57762.0 43533.0 51678.0 52090.0 37074.0 True False 33142.07938048204 33034.26467985982 51083.66218404868 47251.52460374156 44879.25547850855 54732.85903581049 39409.23908837345 50321.50725736703 52851.717705401774 43795.222722377504 0.7567510180407838 0.7542892266872914 1.1664208790048483 1.078919609640392 1.0247523060449502 1.2497449638004539 0.899852464233205 1.149018183475406 1.206791846691461 1.0 15.418485885662957 -5.25440426409305 24.784214939902228 1.0974567259615282 0.755520063074593 0.6584598286970151 0.0983556660537841 270.49260049246305 952919.2962178418 0.02425420179402892 0.06121746739501 5.566673325209308e-06 5.25440426409305 -0.34193666288693525 ANVVTT(ph)PSTNRK ddPTM_PC-9_Lapatinib_30min_R1 1 ANVVTTPSTNRK 12 1 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;E9PDP5 Q8IWZ3-6 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 1 ANVVT(0.035)T(0.955)PS(0.005)T(0.005)NRK 63.894 0.038742 17553000.0 56285.0 49702.0 47101.0 48785.0 49513.0 38608.0 39526.0 30896.0 35881.0 30676.0 True False 55482.365578595105 49586.91807268179 43228.53759511789 52372.81164198926 46600.74268630335 36956.82583964373 41572.462877796665 32331.54095139327 31839.703936319427 35978.30572679936 1.5421061236151443 1.3782449470861466 1.2015167674479459 1.4556775418965335 1.295245613847558 1.0271975039701633 1.1554869535401817 0.8986398969674187 0.8849695196347952 1.0 15.134839629032204 -6.9008130547801425 0.9034733170708333 0.9218426251432986 1.408173991122492 0.7742893304373976 0.1043650760803324 0.2764932622089896 0.47845549793258446 0.07009889183090641 0.05632654631843117 1.256570747315959e-07 6.9008130547801425 0.48633136597919335 APAASEGNHTDGAEEAAGSCAQAPS(ph)HSPPNKPK ddPTM_PC-9_AZD4547_30min_R2 1 APAASEGNHTDGAEEAAGSCAQAPSHSPPNKPK 33 1 Q92560;F8W6N3 Q92560 BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1;Ubiquitin carboxyl-terminal hydrolase 1 APAASEGNHTDGAEEAAGS(0.054)CAQAPS(0.856)HS(0.09)PPNKPK 63.297 5.116399999999999e-05 10745000.0 23244.0 23494.0 52145.0 66741.0 55676.0 50529.0 40352.0 59011.0 46087.0 57780.0 True False 30635.108494765373 31087.976049789486 51453.52322906227 51354.893588171064 47946.34843771521 47369.413642225234 43943.249827817934 49892.20588787803 48523.064731524726 55757.13978686326 0.5494383071274972 0.5575604517847598 0.9228149690918158 0.9210460540924411 0.859914059813586 0.8495667787712771 0.7881187951138635 0.8948128630449037 0.8702574220451148 1.0 15.766868935713743 -5.256383115420395 24.98758515988751 0.8797518375564494 0.5534993329620154 0.8642936753737316 0.052981623236163226 135.65244387390567 670375.9899551184 0.013668105956981582 0.03387114451053767 5.541366623785251e-06 5.256383115420395 -0.326252504594434 APAASEGNHTDGAEEAAGSCAQAPS(ph)HSPPNKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APAASEGNHTDGAEEAAGSCAQAPSHSPPNKPK 33 1 Q92560;F8W6N3 Q92560 BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1;Ubiquitin carboxyl-terminal hydrolase 1 APAASEGNHTDGAEEAAGS(0.028)CAQAPS(0.539)HS(0.433)PPNKPK 53.678999999999995 0.00071822 9099700.0 7667.0 10002.0 13654.0 15094.0 19327.0 19666.0 17616.0 17232.0 14608.0 10719.0 True False 8964.871669847445 10994.932459084821 13979.563143083351 14248.332115408262 15540.013090030374 18634.680339985618 15947.284951204536 16779.67825881321 14821.61436437914 12662.269848442696 0.7079987851427771 0.868322393274304 1.1040329506800604 1.125258921658555 1.2272691449504691 1.471669816156813 1.2594333513722942 1.3251714313193936 1.1705337622544836 1.0 13.628248426145225 -5.155873957356623 1.055909728344447 1.2662378881388197 0.597738094176614 0.6989907169401015 0.11595490321349294 0.5488838244520473 0.7544341423225357 0.038562890987649596 0.35866831847111785 6.984350772256477e-06 5.155873957356623 -0.6684997939622056 APAASEGNHTDGAEEAAGSCAQAPS(ph)HSPPNKPK ddPTM_PC-9_Lapatinib_30min_R1 1 APAASEGNHTDGAEEAAGSCAQAPSHSPPNKPK 33 1 Q92560;F8W6N3 Q92560 BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1;Ubiquitin carboxyl-terminal hydrolase 1 APAASEGNHTDGAEEAAGS(0.003)CAQAPS(0.755)HS(0.242)PPNKPK 68.835 7.7368e-06 6843900.0 14002.0 15909.0 28959.0 17946.0 28827.0 29184.0 20803.0 23363.0 30399.0 21231.0 True False 13802.328912347682 15872.16368794604 26578.10280497269 19265.808706101034 27131.45253606258 27935.86835122676 21880.07755013925 24448.530270824733 26975.144504338656 24900.750061470742 0.5542937011244576 0.6374170918050074 1.0673615348678727 0.7737039510272131 1.0895837462359592 1.121888629148256 0.878691505120345 0.9818391096842607 1.0833065043320784 1.0 14.603901579419768 -5.187661487192509 4.863901693635963 0.9940781138417821 0.578017673367067 0.7174163172153589 0.10153363772571761 0.11228460650039614 4.9326294194584195 0.02621527921946362 0.07376494954457317 6.491402116949982e-06 5.187661487192509 -0.41606044047471513 APAASEGNHTDGAEEAAGSCAQAPSHS(ph)PPNKPK ddPTM_PC-9_Lapatinib_30min_R1 1 APAASEGNHTDGAEEAAGSCAQAPSHSPPNKPK 33 1 Q92560;F8W6N3 Q92560 BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1;Ubiquitin carboxyl-terminal hydrolase 1 APAASEGNHTDGAEEAAGS(0.004)CAQAPS(0.268)HS(0.728)PPNKPK 50.493 0.002337 6658800.0 9710.9 9200.2 17844.0 13712.0 20715.0 19185.0 14554.0 15267.0 20977.0 11928.0 True False 9572.420785239037 9178.897502158605 16376.935199831923 14720.42622189109 19496.58442725697 18364.50227241932 15307.534906731076 15976.360554923636 18614.349362397174 13989.738906939061 0.6842458496842292 0.6561164267051312 1.1706390883184237 1.0522302324448385 1.3936346172684078 1.3127122953888959 1.0941973262373306 1.1420056272100396 1.3305716058191948 1.0 13.772081417021436 -5.273880454577397 5.882914126941765 1.1972384543827996 0.6665073960610567 0.7474177305221139 0.12008373144096528 0.06935919665868305 10.004120600114979 0.03173162961710329 0.07349491681215913 5.322547494136578e-06 5.273880454577397 -0.5307310583217429 APAGQEEPGT(ph)PPSSPLSAEQLDR ddPTM_PC-9_Lapatinib_30min_R1 2 APAGQEEPGTPPSSPLSAEQLDR 23 0 P13051;Q68DM5;F5GYA2;P13051-2 P13051 UNG;DKFZp781L1143 Uracil-DNA glycosylase 1 APAGQEEPGT(1)PPSSPLSAEQLDR;APAGQEEPGT(1)PPSSPLSAEQLDR 97.06299999999999 1.7362e-05 6361800.0 20278.0 14113.1 19640.4 14468.7 18517.4 15246.7 13875.400000000001 14107.5 16667.1 13353.4 True False 19988.832001470226 14080.421984056273 18025.642126136463 15532.776464168292 17428.242938609143 14594.63418279362 14593.800319146385 14762.985951960783 14789.875685656183 15661.517397712942 1.276302384620101 0.8990458348635135 1.150951192556141 0.9917797918122895 1.112806792345306 0.93187868149512 0.931825438656252 0.9426280721762393 0.9443450024718522 1.0 13.934936377370125 -6.7683181067507086 24.985842982813985 0.9454052972823266 1.0741352702116431 0.33779370623341354 0.09437333498264779 188.89823604973927 686136.7924938079 0.030372964530803685 0.0273706764841287 1.704833196035679e-07 6.7683181067507086 0.12872997292931654 APAPAPPGT(ph)VTQVDVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APAPAPPGTVTQVDVR 16 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;H0YFG1 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 APAPAPPGT(0.998)VT(0.002)QVDVR 114.56 0.0014916999999999999 0.0 3141.8 5048.1 3921.6 7721.3 5215.4 5196.8 5515.4 5715.2 3326.4 4177.5 True False 3673.644686621453 5549.2420062693545 4015.1058167508204 7288.700593792351 4193.479809062161 4924.270659556456 4992.941383961936 5565.18205575495 3375.042307069469 4934.847680928193 0.7444291950122519 1.1245011730991463 0.8136230490493318 1.4769859304799098 0.8497688439845444 0.997856667103908 1.0117721370121024 1.1277312726921285 0.6839202596086328 1.0 12.268789839787347 -8.250762629142386 24.967907500200965 0.8419601116615929 1.0238170842310699 0.10337739885797281 0.20726833275604262 1338.7290285436102 3130676.885470614 0.13473071757801705 0.0497900407821097 5.613547099338037e-09 8.250762629142386 0.18185697256947697 APAPLGTVADSLRAS(ph)DGQLQAK ddPTM_PC-9_AZD4547_30min_R2 3 APAPLGTVADSLRASDGQLQAK 22 1 Q9BRG2;Q9BRG2-2 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 APAPLGTVADS(0.016)LRAS(0.984)DGQLQAK;APAPLGT(0.001)VADS(0.003)LRAS(0.996)DGQLQAK;APAPLGTVADS(0.051)LRAS(0.949)DGQLQAK 85.087 0.00010849 118758000.0 60846.9 61523.4 84555.7 136838.0 120733.5 105142.7 73095.0 94567.1 97675.3 105650.5 True False 80194.94850585682 81409.63589433987 83434.43617028712 105292.11322602519 103971.7375369078 98568.1103477287 79600.31339622215 79953.92763077297 102838.21694992301 101951.70815250956 0.7865973994853839 0.7985117402109555 0.8183721261979992 1.032764581722542 1.019813590385131 0.9668117595467911 0.7807648821062227 0.784233330462398 1.0086953795427078 1.0 16.637526421664887 -5.598575124332581 9.372150872020176 0.9303781380356098 0.7964996102879128 0.35489677278887444 0.08639395735798909 0.4064374177093338 46.392090092275495 0.026095140832063685 0.045258423026644415 2.52014120748266e-06 5.598575124332581 -0.13387852774769693 APAPLGTVADSLRAS(ph)DGQLQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 APAPLGTVADSLRASDGQLQAK 22 1 Q9BRG2;Q9BRG2-2 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 APAPLGT(0.004)VADS(0.06)LRAS(0.937)DGQLQAK;APAPLGT(0.001)VADS(0.323)LRAS(0.675)DGQLQAK;APAPLGT(0.002)VADS(0.005)LRAS(0.992)DGQLQAK;APAPLGTVADS(0.003)LRAS(0.996)DGQLQAK 72.271 0.0006544 96085400.0 93026.0 88413.0 107753.0 117262.0 127023.0 124244.0 130074.0 112892.0 113547.0 97627.0 True False 108773.46445274937 97190.05833883863 110322.24017552809 110692.19030853364 102133.75499223504 117728.42592093823 117752.44906579114 109928.70461896135 115207.41006518068 115326.00228509349 0.943182476609691 0.8427419351498753 0.9566120214832751 0.9598198855007151 0.8856090818075325 1.0208315868775697 1.021039893281823 0.9531996465741553 0.9989716783937447 1.0 16.815358305192433 -6.765301059829748 24.999890881706204 0.9972730022273526 0.9179483338628683 0.5467549686659443 0.03695857602759713 82.73770381712797 535626.5227238816 0.013067681144581737 0.01195639187294484 1.716717918463536e-07 6.765301059829748 -0.07932466836448426 APAPLGTVADSLRAS(ph)DGQLQAK ddPTM_PC-9_Lapatinib_30min_R1 2 APAPLGTVADSLRASDGQLQAK 22 1 Q9BRG2;Q9BRG2-2 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 APAPLGT(0.103)VADS(0.368)LRAS(0.53)DGQLQAK;APAPLGT(0.012)VADS(0.093)LRAS(0.895)DGQLQAK 53.481 0.0087508 88229000.0 73548.0 56515.0 61228.0 58214.0 70996.0 62299.0 60368.0 56445.0 62281.0 53975.0 True False 72499.1920329485 56384.142989771244 56194.07018691485 62495.25175621115 66820.15486350641 59634.61699606211 63493.55965710744 59067.64076260333 55266.25793199498 63304.506832833285 1.145245349188098 0.8906813402506004 0.8876788241207723 0.9872164697726954 1.055535509343068 0.9420279847300261 1.002986403871266 0.9330716518901546 0.8730224860282899 1.0 15.950020592535223 -7.849199280263104 6.938367494999974 0.926040348813053 0.9805809581829878 0.07891837365670662 0.07731651623708227 0.5918166412670325 39.022074759012064 0.04245141345951472 0.020254551940207262 1.4151442781850507e-08 7.849199280263104 0.05454060936993488 APAPVVLGS(ph)PVVLGPPVGQAR ddPTM_PC-9_AZD4547_30min_R2 2 APAPVVLGSPVVLGPPVGQAR 21 0 A0A0C4DFM2;Q6ZN55;Q6ZN55-2 A0A0C4DFM2 ZNF574 Zinc finger protein 574 1 APAPVVLGS(1)PVVLGPPVGQAR;APAPVVLGS(1)PVVLGPPVGQAR 108.47 5.461e-05 10985700.0 21179.5 23131.9 28014.3 36828.1 32575.7 29514.5 22922.4 32840.5 26042.8 26125.2 True False 27914.140439032995 30608.834306040924 27642.81207778155 28337.950533473027 28053.126352512383 27668.95364925997 24962.449193427183 27765.755324615027 27419.369240570046 25210.564699891995 1.1072397929726892 1.2141272784013464 1.0964773065118996 1.1240506061966327 1.1127527957607617 1.0975142357433392 0.9901582725568271 1.1013539623225488 1.087614242956149 1.0 14.621740813517796 -6.451390621946884 0.7535351803905235 1.048986536547188 1.15578913678458 0.4435887929535933 0.04449733444587398 0.6775271393117198 0.8530209375483713 0.027667870702670416 0.03854921732523427 3.5367908476645135e-07 6.451390621946884 0.10680260023739208 APAPVVLGS(ph)PVVLGPPVGQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APAPVVLGSPVVLGPPVGQAR 21 0 A0A0C4DFM2;Q6ZN55;Q6ZN55-2 A0A0C4DFM2 ZNF574 Zinc finger protein 574 1 APAPVVLGS(1)PVVLGPPVGQAR;APAPVVLGS(1)PVVLGPPVGQAR 166.21 2.3049e-08 7868100.0 22626.0 28493.0 27639.0 26571.0 33574.0 25735.0 33972.0 21284.0 21943.0 25920.0 True False 26456.134916129933 31321.596736323114 28298.018581491204 25082.313014344305 26995.415712975613 24385.411296121718 30753.926224019095 20725.317552262084 22263.87486292247 30619.090817392913 0.8640405123035774 1.0229433957761787 0.924195259430001 0.8191723641936655 0.8816530795761283 0.7964119980424041 1.0044036384826158 0.6768756680550829 0.7271239696730533 1.0 14.902143824610786 -5.667688579393658 4.9423666947451865 0.8366225280609861 0.9499485844377563 0.141399281038049 0.10448306604736128 0.3575117974113843 14.51759332449257 0.028533206482660008 0.05022025863644868 2.1493711765134055e-06 5.667688579393658 0.11332605637677018 APAPVVLGS(ph)PVVLGPPVGQAR ddPTM_PC-9_Lapatinib_30min_R1 2 APAPVVLGSPVVLGPPVGQAR 21 0 A0A0C4DFM2;Q6ZN55;Q6ZN55-2 A0A0C4DFM2 ZNF574 Zinc finger protein 574 1 APAPVVLGS(1)PVVLGPPVGQAR;APAPVVLGS(1)PVVLGPPVGQAR 128.94 1.9750999999999998e-05 7632700.0 14217.1 19120.8 18191.5 17701.3 22010.8 20239.7 24852.8 22105.0 23350.6 20970.1 True False 14014.361546903165 19076.52696237844 16695.865091220705 19003.112651805764 20716.168018897788 19374.09521204511 26139.556378315665 23132.078998269953 20720.609535281088 24594.753844098148 0.5698110107439073 0.7756339861460381 0.6788384708809398 0.7726490280107368 0.8423002787592005 0.7877328366388263 1.062810245795089 0.9405289902432106 0.8424808667175697 1.0 14.586062995510222 -6.137738554446427 0.564254315484459 0.9673082380509014 0.6094888108294932 0.6866722456336135 0.07799116881170089 0.7038128185087358 0.4355106489875405 0.057278967899896976 0.13770928198228938 7.282180603426772e-07 6.137738554446427 -0.35781942722140814 APAS(ph)PGAGSDAQGPQFGWDHSLHK ddPTM_PC-9_Lapatinib_30min_R1 1 APASPGAGSDAQGPQFGWDHSLHK 24 0 Q5T6F0 Q5T6F0 DCAF12 DDB1- and CUL4-associated factor 12 1 APAS(0.997)PGAGS(0.003)DAQGPQFGWDHSLHK 84.89 1.9452999999999998e-05 6695600.0 12387.0 13432.0 16006.0 13323.0 16719.0 21152.0 19038.0 17864.0 20155.0 16531.0 True False 12210.359108502402 13400.899029259617 14690.048464946736 14302.817864225128 15735.621290818694 20247.37826772029 20023.694486350567 18694.02665573825 17884.931658440903 19388.361323827085 0.6297777777380615 0.6911826536258507 0.757673545463256 0.7377012231893914 0.811601404987259 1.0443058043712816 1.0327687911274224 0.9641880684761357 0.9224571050499992 1.0 14.24290325365475 -6.553474734137181 2.9510552420222895 0.9928692719277092 0.7080922075231235 0.8959455269622679 0.04645955102007882 0.08659123576144503 1.542415081592201 0.017777847189716266 0.01858156871037309 2.795923380722254e-07 6.553474734137181 -0.2847770644045857 APASVLPAAT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 APASVLPAATPR 12 0 P13861-2;P13861;C9J830 P13861-2 PRKAR2A cAMP-dependent protein kinase type II-alpha regulatory subunit 1 APASVLPAAT(1)PR;APASVLPAAT(1)PR 117.7 0.0015124000000000001 23953000.0 48041.0 43443.0 53379.0 98523.0 90583.0 98986.0 73631.0 102011.0 72122.0 92519.0 True False 63317.038685124026 57485.100175832304 52671.15958278096 75810.04451517618 78007.11402639486 92796.38977199826 80184.01635785232 86247.5439295779 75934.2216800188 89279.93797059199 0.7091967145629077 0.6438747772737855 0.5899551543161955 0.8491274326394282 0.8737362032228305 1.0393868082946536 0.898119086779207 0.9660349893834724 0.8505183068678974 1.0 16.446048404369435 -5.9491188997772815 2.9467761227509395 0.9377786105570772 0.6472448965141486 0.8149817078446613 0.061436989001815656 0.10216119180873667 1.8075600663595404 0.01812276772858613 0.02790712770585176 1.1242971252971847e-06 5.9491188997772815 -0.2905337140429286 APASVLPAAT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APASVLPAATPR 12 0 P13861-2;P13861;C9J830 P13861-2 PRKAR2A cAMP-dependent protein kinase type II-alpha regulatory subunit 1 APASVLPAAT(1)PR;APASVLPAAT(1)PR 89.44 0.018313999999999997 9331900.0 34727.0 29981.0 46830.0 40191.0 62245.0 43569.0 42227.0 40821.0 41638.0 30338.7 True False 40605.595210485466 32957.31554247368 47946.60480376402 37939.22857098005 50048.53907947119 41284.164941159004 38226.95286299464 39749.49200342467 42246.87697864311 35838.86614898296 1.1330044606234781 0.9195970487869062 1.3378382174382673 1.0586057162987756 1.3964877926499768 1.151938366842852 1.066633991825644 1.1091168966725997 1.1788006016435315 1.0 15.129237374447326 -10.234485406099385 8.111306919939889 0.9999999972585195 1.1498908032017976 0.1083003620346411 0.12931427290099637 8.964618956693627e-11 0.0 0.12314243235939971 0.02986642680078137 5.827933584793425e-11 10.234485406099385 0.14989080594327808 APASVLPAAT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 APASVLPAATPR 12 0 P13861-2;P13861;C9J830 P13861-2 PRKAR2A cAMP-dependent protein kinase type II-alpha regulatory subunit 1 APASVLPAAT(1)PR 124.48 0.00078491 8890100.0 42446.0 34933.0 38747.0 37504.0 39500.0 30586.0 30419.0 30325.0 36762.0 23611.0 True False 41840.7122563569 34852.11478477711 35561.37122774534 40262.16926967645 37176.68765998792 29277.90807944838 31993.946978689884 31734.010206855273 32621.476438978174 27692.129890320106 1.5109243103392522 1.2585566701736368 1.2841688728383422 1.4539210031565775 1.3425001185258478 1.0572645800597156 1.155344392266248 1.1459577263483811 1.1780053238296107 1.0 14.757188399813725 -6.716705895713794 7.695977410076308 1.1195707281808345 1.3647122290680278 0.7072502827893083 0.08430733844097828 0.1362957493319 19.840409135485743 0.02766487005508016 0.027448486371365828 1.919968503470175e-07 6.716705895713794 0.24514150088719333 APDFVFYAPR ddPTM_PC-9_AZD4547_30min_R2 2 APDFVFYAPR 10 0 P15311;E7EQR4;A0A2R8Y7M3;A0A2R8Y5S7;P35241;P35241-5;P35241-4;P26038 P15311;A0A2R8Y7M3;P26038 EZR;RDX;MSN Ezrin;Radixin;Moesin 0 ; 93.178 0.032067 8228700.0 16942.5 16318.7 27892.0 45575.0 35221.0 28442.0 28292.0 30655.0 27533.0 31024.0 False True 22329.86257410783 21593.400645428614 27522.133855690954 35068.3878767309 30331.17210871409 26663.51724380394 30809.933191133674 25917.9741318212 28988.338170266445 29937.859202970674 0.7458737253962394 0.7212740396376085 0.9193086809947983 1.1713725967837785 1.0131376429783059 0.8906287207456094 1.029129470556013 0.8657257005620966 0.9682836028365712 1.0 14.869683440368558 -5.353443531113469 4.250843841644858 0.9873855035470241 0.7331760465832841 0.6207786556564037 0.07899861641013743 0.14409306236437852 4.563360815300902 0.022157596684758436 0.04983573218307594 4.431558318217697e-06 5.353443531113469 -0.2542094569637401 APDFVFYAPR ddPTM_PC-9_Lapatinib_30min_R1 2 APDFVFYAPR 10 0 P15311;E7EQR4;A0A2R8Y7M3;A0A2R8Y5S7;P35241;P35241-5;P35241-4;P26038 P15311;A0A2R8Y7M3;P26038 EZR;RDX;MSN Ezrin;Radixin;Moesin 0 ; 114.89 0.0053886 16478600.0 53721.0 44489.0 49886.0 47740.0 47947.0 48042.0 50514.0 38375.0 45681.0 41253.0 False True 52954.92868877514 44385.988453896025 45784.56564552878 51250.95885597143 45126.85172742892 45987.35565137187 53129.36775309973 40158.04259482513 40535.92473774444 48383.52608383273 1.0944826261116578 0.9173781252939216 0.9462841870226489 1.0592646506823498 0.9326904295738788 0.9504754897708554 1.0980879661611271 0.8299941291018033 0.837804269732409 1.0 15.56222829310639 -7.781240776670843 24.99813931060218 0.8754243873161266 0.9923878453707418 0.2981777201806366 0.07624900584045416 288.792750461211 364579.25293718197 0.04000589161969584 0.01925882306142991 1.6548522444949042e-08 7.781240776670843 0.11696345805461517 APDMS(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 1 APDMSPQR 8 0 Q8NC74 Q8NC74 RBBP8NL RBBP8 N-terminal-like protein 1 APDMS(1)PQR 79.48899999999999 0.018175999999999998 20765000.0 34823.0 36908.0 56675.0 72419.0 68267.0 61081.0 54558.0 69329.0 49644.0 57099.0 True False 45895.98963660357 48837.78922472249 55923.45246921281 55723.918412396604 58789.30542419541 57261.59541413366 59413.5563071494 58615.79607193062 52268.08048976532 55099.981389582965 0.8329583509674383 0.8863485611622296 1.0149450337162098 1.0113237247468763 1.0669569016462488 1.0392307577976672 1.078286322586344 1.0638079105234026 0.9486043220269937 1.0 15.749764211065285 -5.171622927959522 1.9784694246737906 1.0369510103950639 0.8250375462947878 0.779116800793578 0.03631477154317659 0.17358185606267607 1.165911170764913 0.010129259226189031 0.04959447668781469 6.735612155778214e-06 5.171622927959522 -0.21191346410027612 APDMS(ph)PQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APDMSPQR 8 0 Q8NC74 Q8NC74 RBBP8NL RBBP8 N-terminal-like protein 1 APDMS(1)PQR 72.243 0.029245999999999998 17378000.0 56164.0 52025.0 63788.0 76478.0 81582.0 66526.0 73651.0 70875.0 64955.0 49999.0 True False 65671.45591043583 57189.69817875303 65308.947837337146 72193.18560502132 65596.59274128723 63037.25944767028 66674.24409293635 69014.60634826974 65904.84399221298 59063.42290813376 1.1118802920138933 0.9682760558544822 1.1057426850949286 1.222299386835561 1.1106127872628555 1.0672808371725655 1.1288584509678745 1.1684830128388237 1.1158317745099238 1.0 15.849977347086249 -5.500332496892471 24.108110394260525 1.124745222584888 1.0393109368961244 0.17268288189493364 0.06395443297154306 672.4790749003109 719061.8177712149 0.016133331559397113 0.03313737883093926 3.159857539383348e-06 5.500332496892471 -0.08543428568876354 APDMS(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 2 APDMSPQR 8 0 Q8NC74 Q8NC74 RBBP8NL RBBP8 N-terminal-like protein 1 APDMS(1)PQR;APDMS(1)PQR 72.607 0.028372 22314000.0 100305.0 84247.0 114789.0 92224.0 94357.0 92295.0 89131.0 93760.0 99293.0 73451.0 True False 98874.63230631594 84051.93124762044 105351.49151835394 99006.46061024535 88807.10677299954 88347.7580001534 93745.76705866748 98116.43188770807 88109.57673835648 86146.9074826947 1.1477444193359814 0.9756813529783979 1.2229283046465373 1.1492746925376733 1.0308798001929347 1.0255476439232691 1.0882081527708845 1.1389431699265329 1.0227828173176854 1.0 16.394511386801064 -6.262098877831806 24.989199580104746 1.0585891862534962 1.1203925686170069 0.20823176668267795 0.06851686232691089 117.60290384253942 4456163.890491653 0.021244005726462276 0.02558486947025577 5.468914354180517e-07 6.262098877831806 0.061803382363510684 APDSGLPSGGGGRPGCAYPGS(ph)PGPGAR ddPTM_PC-9_AZD4547_30min_R2 2 APDSGLPSGGGGRPGCAYPGSPGPGAR 27 1 Q6PJ61 Q6PJ61 FBXO46 F-box only protein 46 1 APDS(0.001)GLPS(0.002)GGGGRPGCAY(0.145)PGS(0.852)PGPGAR;APDS(0.007)GLPS(0.027)GGGGRPGCAY(0.221)PGS(0.745)PGPGAR 48.115 0.012559 24280000.0 11085.599999999999 11175.9 16940.1 24225.0 20689.1 13994.0 14494.599999999999 19461.7 15883.900000000001 14222.1 True False 14610.590205195791 14788.291118363937 16715.46320553528 18640.30052251905 17816.775584861214 13118.952967786805 15784.591320239142 16454.34145037562 16723.49052637546 13724.188607870328 1.0645868125724491 1.0775348212486227 1.2179563894910017 1.358207836915729 1.2982024725777912 0.9559000785127332 1.1501292915187167 1.1989300001997676 1.218541292618577 1.0 13.744433237267758 -6.7196453708410555 24.999847398114618 1.1199710510592789 1.205731190398477 0.15447876183889353 0.11246253789393547 359.3745984117127 214965.23055377408 0.04065308586146425 0.04065265417545563 1.9070172836674248e-07 6.7196453708410555 0.08576013933919824 APDSGLPSGGGGRPGCAYPGS(ph)PGPGAR ddPTM_PC-9_Lapatinib_30min_R1 2 APDSGLPSGGGGRPGCAYPGSPGPGAR 27 1 Q6PJ61 Q6PJ61 FBXO46 F-box only protein 46 1 APDS(0.001)GLPS(0.024)GGGGRPGCAY(0.456)PGS(0.519)PGPGAR;APDSGLPSGGGGRPGCAY(0.038)PGS(0.962)PGPGAR 69.07 0.00011874 16700100.0 17902.6 16040.6 15626.2 15877.4 16455.3 18064.8 15764.599999999999 15814.300000000001 16411.2 14492.8 True False 17647.30564106525 16003.45897623152 14341.474154876358 17045.07696145373 15487.431606364538 17292.210615105585 16580.81385121979 16549.090110940517 14562.797838402661 16997.86116955788 1.0382074229827505 0.9414983930385741 0.8437222784570716 1.0027777490017633 0.9111400223753782 1.017316851962226 0.9754647179325717 0.9735983807526865 0.8567429568423428 1.0 14.053065603900743 -4.759492552459199 24.80353389132611 0.9465876218895805 1.038207549943754 0.1874314439029411 0.05701936562745036 80.12253578231662 1020501.7704847764 0.013910817403304496 0.0877258730120637 1.7398325334684372e-05 4.759492552459199 0.09161992805417352 APDVDVNIAGPDAALKVDVKS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 APDVDVNIAGPDAALKVDVKSPK 23 2 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 APDVDVNIAGPDAALKVDVKS(1)PK 42.208999999999996 0.027913 7695400.0 31079.0 24169.0 29431.0 47891.0 48770.0 29050.0 29693.0 26341.0 33490.0 37191.0 True False 40961.4755166414 31981.15659944505 29040.725710126215 36850.46985857421 41999.127331478005 27233.498907689518 32335.619477037017 22270.60370596321 35260.213028809936 35888.95441005936 1.1413393393584144 0.8911141916823581 0.8091828304138711 1.026791403213612 1.1702521854385932 0.7588267575735281 0.9009908482586949 0.6205420044146216 0.9824809222897506 1.0 15.13125227179244 -6.78925908038401 24.99808446828009 0.8318784049143533 0.991285097856369 0.21688630759495975 0.1430817640667787 335.24851019569843 301243.48576615093 0.05031215185304588 0.04438048601591102 1.6245793163043188e-07 6.78925908038401 0.1594066929420157 APDVDVNIAGPDAALKVDVKS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APDVDVNIAGPDAALKVDVKSPK 23 2 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 APDVDVNIAGPDAALKVDVKS(1)PK 58.835 0.0020824000000000003 3862100.0 20416.0 9536.6 15988.0 36221.0 49258.0 59174.0 58962.0 90368.0 67062.0 57841.0 True False 23872.02556561958 10483.330622806268 16369.214554827655 34191.654800066426 39606.248501511654 56070.81127012651 53376.692512086825 87995.93575281074 68042.65488116043 68327.11543089582 0.3493785068354465 0.1534285555111546 0.23957128076602371 0.500411214265981 0.5796563816830279 0.8206231291416802 0.7811934131197233 1.2878625886352164 0.9958367838603828 1.0 16.06017060132198 -6.658050775511705 0.826486493033105 1.097098481844584 0.2141866177095006 0.8795717365226461 0.12139545572435534 0.18914845748154038 0.2849473841390295 0.07548293938932056 0.0800711820233645 2.1976029251585127e-07 6.658050775511705 -0.8829118641350833 down APDWVDAEECHR ddPTM_PC-9_AZD4547_30min_R2 1 APDWVDAEECHR 12 0 I3L1P5;O14964-2;O14964 I3L1P5 HGS Hepatocyte growth factor-regulated tyrosine kinase substrate 0 114.72 0.00063428 4481700.0 26056.0 26958.0 37791.0 45886.0 36043.0 35152.0 27675.0 42146.0 26043.0 31164.0 False True 34341.26600153186 35671.646307577466 37289.866647799245 35307.691631633 31039.051597466936 32953.93988306716 30138.021386421042 35633.30411873221 27419.579812161737 30072.957845583365 1.1419317706580485 1.1861701961856188 1.2399800125838232 1.1740678057984386 1.0321249993713357 1.095799756454848 1.002163523161631 1.1848952238652328 0.9117686378890292 1.0 14.87617915166133 -6.2163294405101786 5.465566707949246 1.0480508688328471 1.1909822512106687 0.512413640128069 0.07017641333247551 0.17097806504576363 12.746374401867243 0.01983629241270097 0.025412264954251 6.076738663908385e-07 6.2163294405101786 0.14293138237782155 APDWVDAEECHR ddPTM_PC-9_Lapatinib_30min_R1 2 APDWVDAEECHR 12 0 I3L1P5;O14964-2;O14964 I3L1P5 HGS Hepatocyte growth factor-regulated tyrosine kinase substrate 0 ; 134.18 4.752e-05 7192700.0 40601.0 57787.0 63638.0 49572.0 60061.0 58262.0 40850.0 47135.0 59889.0 49548.0 False True 40022.02229468848 57653.197751922686 58405.92928978389 53217.690247344326 56528.330064469235 55770.27007535546 42965.013119414914 49325.06417477738 53143.67016087165 58112.30578143998 0.6887013302347881 0.992099641834141 1.0050526907235142 0.9157731659710032 0.9727428520401846 0.9596981108460417 0.7393444906661605 0.8487886259459164 0.9144994239386174 1.0 15.826556078635326 APEATVTLPVFIGNIAVNHAPVS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 APEATVTLPVFIGNIAVNHAPVSPR 25 0 Q5T370;Q8N5I2 Q5T370 ARRDC1 Arrestin domain-containing protein 1 1 APEATVTLPVFIGNIAVNHAPVS(1)PR 118.81 3.2366e-09 1959900.0 3131.1 5876.9 5579.3 3279.8 5210.1 9049.9 13077.0 15884.0 9622.8 6450.3 True False 4126.724669074163 7776.492995956744 5505.314836550145 2523.6927824048717 4486.767547872334 8484.008322364863 14240.827666494233 13429.492778008416 10131.441562664448 6224.476960318516 0.6629833631616483 1.2493407953041582 0.8844622402246677 0.4054465617743616 0.7208264367393111 1.3630074263992011 2.287875392146284 2.1575295183229675 1.6276775747188252 1.0 12.603736897994203 -6.965216287273703 4.048237285462439 1.8655432033344403 0.8008089773205079 0.5901936670031642 0.38346799548871174 0.1414929418606902 5.107756806866503 0.14384843317170862 0.12177288374242201 1.0833872312971603e-07 6.965216287273703 -1.0647342260139325 APEATVTLPVFIGNIAVNHAPVS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APEATVTLPVFIGNIAVNHAPVSPR 25 0 Q5T370;Q8N5I2 Q5T370 ARRDC1 Arrestin domain-containing protein 1 1 APEATVTLPVFIGNIAVNHAPVS(1)PR 134.98 3.1519e-07 2734700.0 2069.5 3657.1 4427.2 3153.0 4910.0 3970.7 4822.8 2850.8 2111.5 3023.1 True False 2419.825475511841 4020.1527190680927 4532.761238249495 2976.3476321639228 3947.9207467299184 3762.4695019821434 4365.949469951706 2775.9695206722795 2142.376692934458 3571.1640991535664 0.6776013110361928 1.12572612387679 1.2692671387808379 0.8334390550323278 1.105499673808227 1.0535694797318107 1.2225563846216194 0.7773290287417027 0.5999098986916456 1.0 11.802178713628246 -7.830061836932167 10.32052938731177 0.7651646206161268 1.0479980544946008 0.2642097225665999 0.18831233048318943 0.525202748941572 75.39682810479128 0.10006392418142807 0.048045732861029755 1.4788978006114257e-08 7.830061836932167 0.28283343387847404 APEEGDAEVMQLGS(ph)SSPPPAR ddPTM_PC-9_Lapatinib_30min_R1 1 APEEGDAEVMQLGSSSPPPAR 21 0 Q6NUJ5-2;Q6NUJ5 Q6NUJ5-2 PWWP2B PWWP domain-containing protein 2B 1 APEEGDAEVMQLGS(0.333)S(0.333)S(0.333)PPPAR 165.17 2.7466e-25 0.0 581.76 2246.9 2300.4 950.87 945.67 2423.3 2132.4 896.13 2259.5 1039.6 True False 573.4639957182821 2241.697441099124 2111.269991800792 1020.8001518093334 890.0475498587542 2319.661107988206 2242.805238086668 937.7674712834037 2005.0113164101838 1219.293474820074 0.47032482955172533 1.8385216417482442 1.7315519482398143 0.8372062779717316 0.7299699114604832 1.902463316578077 1.8394301982282235 0.7691072663386361 1.644404204415229 1.0 10.251829698322831 -4.740841190657119 24.81856522518276 1.3652403749811761 0.4703212884810342 0.2539188670076833 0.46051496661545316 2149.1475437836007 2589341.3578207195 0.11809609666926418 4.978626526338534 1.8161796674595222e-05 4.740841190657119 -0.894919086500142 APELPNTSS(ph)SPSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APELPNTSSSPSLK 14 0 Q9UN79 Q9UN79 SOX13 Transcription factor SOX-13 1 APELPNT(0.014)S(0.004)S(0.491)S(0.491)PSLK;APELPNT(0.123)S(0.123)S(0.373)S(0.373)PS(0.008)LK 205.66 9.334e-11 26771000.0 90223.0 88052.0 89849.0 100979.0 112669.0 102932.0 107812.0 94225.0 82490.0 77778.0 True False 105495.97191452264 96793.2206446048 91991.34091423002 95321.47400833498 90592.31825118378 97534.06471857 97599.26686871392 91751.6935896397 83696.26019425214 91878.53570969071 1.1482112889550073 1.0534911108122473 1.0012277645009031 1.0374727162557633 0.9860008929335683 1.0615544094732758 1.0622640654298088 0.9986194586246804 0.9109446460782509 1.0 16.487440243870843 -4.773807464691217 2.2252000008331225 1.011274711101121 1.1858795491182563 0.518720125442652 0.04120578602889463 0.5692183122770197 3.244005351683527 0.011356297346320116 0.2010543785162744 1.683420204545937e-05 4.773807464691217 0.17460483801713522 APELPNTSS(ph)SPSLK ddPTM_PC-9_Lapatinib_30min_R1 1 APELPNTSSSPSLK 14 0 Q9UN79 Q9UN79 SOX13 Transcription factor SOX-13 1 APELPNT(0.014)S(0.004)S(0.491)S(0.491)PSLK 220.25 8.218999999999999e-16 22204000.0 102270.0 77962.0 92200.0 85451.0 86489.0 88594.0 79137.0 75341.0 75711.0 58464.0 True False 100811.61104597895 77781.48377897106 84619.67190229222 91735.35159617956 81401.88706391637 84805.04114270097 83234.32663968507 78841.61790584298 67183.62990782535 68569.42450161678 1.4702122962050226 1.1343464575400815 1.2340729489467568 1.337846310698095 1.1871455485527227 1.2367763293784297 1.2138694067313123 1.149807198746199 0.9797899048466018 1.0 16.065277793365482 -8.021121094678282 1.5762747837895323 0.9790552124473673 1.2589898575214598 0.6059559072227549 0.08650247637529528 0.26788460650985746 1.191697690661845 0.07370024853550668 0.02429558996626648 9.52530532140893e-09 8.021121094678282 0.2799346450740925 APELPNTSSS(ph)PSLK ddPTM_PC-9_AZD4547_30min_R2 4 APELPNTSSSPSLK 14 0 Q9UN79 Q9UN79 SOX13 Transcription factor SOX-13 1 APELPNT(0.003)S(0.001)S(0.096)S(0.897)PS(0.003)LK;APELPNT(0.002)S(0.002)S(0.189)S(0.794)PS(0.014)LK;APELPNT(0.033)S(0.105)S(0.34)S(0.515)PS(0.008)LK;APELPNT(0.011)S(0.011)S(0.215)S(0.735)PS(0.029)LK 169.02 0.00032717 59352200.0 144883.0 134626.0 173535.0 212146.0 188555.0 181780.0 149078.0 191423.0 153822.0 177545.0 True False 190952.78024639015 178141.221745082 171233.81251424525 163239.017323027 162377.3929462138 170413.26786367598 162345.65319764655 161842.97381293814 161952.7168861631 171329.20359049228 1.1145372548558725 1.0397598191775388 0.9994432293254859 0.9527798758301457 0.9477508185605361 0.9946539427743705 0.9475655626444278 0.9446315655547671 0.9452721047677274 1.0 17.38641155863293 -4.856530304709338 1.1791110819960822 0.9590454109422636 1.1737018363828795 0.8527815719567667 0.020013712058591673 0.4736816740212652 0.6105882325122358 0.006165082863217624 0.1217993638013635 1.3914566967608685e-05 4.856530304709338 0.21465642544061592 APELPNTSSS(ph)PSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APELPNTSSSPSLK 14 0 Q9UN79 Q9UN79 SOX13 Transcription factor SOX-13 1 APELPNT(0.001)SS(0.038)S(0.958)PS(0.003)LK;APELPNTSS(0.234)S(0.765)PS(0.001)LK 206.67 8.042e-11 26922000.0 100161.0 88605.0 85003.0 107121.0 103896.0 97498.0 93480.0 108371.0 82639.0 84825.0 True False 117116.27903007584 97401.11882995491 87029.79389567266 101119.35766096771 83538.32462367654 92385.03324458038 84624.8976634083 105526.37607856594 83847.43903737194 100203.10102566969 1.1687889679190007 0.9720369712410699 0.8685339376211287 1.0091439948057426 0.8336900132689105 0.9219777861057763 0.8445337199866636 1.0531248534068078 0.8367748919855502 1.0 16.612567631324502 -4.784856621266823 3.3352936452760615 0.9199933917047992 1.2011209783660264 0.5000002939321024 0.07411901128527905 0.2399431425778557 4.230688417455008 0.017377501342246263 0.17429090426901303 1.6411314897681995e-05 4.784856621266823 0.28112758666122717 APELPNTSSS(ph)PSLK ddPTM_PC-9_Lapatinib_30min_R1 3 APELPNTSSSPSLK 14 0 Q9UN79 Q9UN79 SOX13 Transcription factor SOX-13 1 APELPNT(0.001)S(0.001)S(0.403)S(0.587)PS(0.008)LK;APELPNTSS(0.286)S(0.712)PS(0.001)LK;APELPNTSS(0.148)S(0.851)PSLK 217.79 1.602e-15 37832500.0 165692.0 137022.0 158612.0 151774.0 140712.0 143663.0 133125.0 123988.0 150133.0 116448.0 True False 163329.2016958088 136704.73397760658 145571.53362002605 162935.9662632222 132435.59681043614 137518.86838481 140017.5611143722 129748.93512044766 133223.44056942244 136575.8816427936 1.1958861237519738 1.0009434486767583 1.065865596978243 1.193006878691597 0.9696850953290118 1.0069044895092292 1.0251997602371707 0.9500135277163985 0.9754536376917612 1.0 17.059343210579662 -6.28725848137822 24.996532473908417 0.9881943559746978 1.1024225242064025 0.5371823883059166 0.05691829651724874 650.347010884036 629625.8654987057 0.017665766279150934 0.020037130169772648 5.161091024171919e-07 6.28725848137822 0.11422816823170467 APEPDLMS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 2 APEPDLMSPTR 11 0 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 APEPDLMS(0.983)PT(0.017)R;APEPDLMS(0.568)PT(0.432)R 85.973 0.025626999999999997 3140200.0 52917.9 52344.1 55548.0 57807.0 52045.4 51828.0 47965.0 71175.0 50297.4 48601.9 True False 69744.69143930235 69263.30668033488 54811.3972255816 44480.48925924701 44819.79457899743 48587.186966875415 52233.792079482715 60176.53918879058 52956.0178798228 46900.36227426702 1.4870821472858728 1.476818159213619 1.1686774806781215 0.9484039589956914 0.9556385581181078 1.0359661335395252 1.1137183072068082 1.2830719480776345 1.129117459053794 1.0 15.517311446197775 -5.326075761431002 3.580668018104337 1.0736682185541888 1.4902282735621415 0.7557133705872273 0.09288744943060062 0.12262026845162549 3.0944709677580287 0.02859813170329158 0.0699826702015481 4.7198069839781135e-06 5.326075761431002 0.4165600550079527 APEPDLMS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APEPDLMSPTR 11 0 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 APEPDLMS(0.984)PT(0.016)R 87.641 0.028019 0.0 20514.0 34476.0 31656.0 37463.0 35358.0 37667.0 40644.0 34970.0 30775.0 28905.0 True False 23986.615030031357 37898.54943605362 32410.79909604856 35364.06956668476 28429.85371952676 35691.676211036174 36793.90608292217 34052.074553777755 31225.026154420066 34145.247688145886 0.7024876565285167 1.1099216436262886 0.9492038069854309 1.0356952126887633 0.8326152435378782 1.04528971460433 1.0775703377221602 0.997271270801164 0.9144764870240017 1.0 15.059397178743037 APEPDLMS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 3 APEPDLMSPTR 11 0 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 APEPDLMS(0.99)PT(0.01)R;APEPDLMS(0.972)PT(0.028)R;APEPDLMS(0.96)PT(0.04)R 96.334 0.0058477 12004600.0 29903.8 33994.3 48537.0 28323.199999999997 48229.0 53003.0 52815.0 57998.0 63116.0 46212.1 True False 29477.366328314693 33915.58828695357 44546.47521823817 30406.182611425436 45392.26504186223 50736.18524602772 55549.502274220285 60692.798812108565 56007.21143905514 54199.79991124738 0.5438648551578442 0.6257511714524893 0.821893720847372 0.5610017502133922 0.8374987567517305 0.9360954344685524 1.0249023495507927 1.119797469944419 1.0333471992658168 1.0 15.725999905158412 -6.688101795864543 1.4826185532705107 1.0575143434850547 0.6429995810601391 0.8378145391173512 0.08007810753515583 0.1507271402078705 0.689205865160749 0.035102988293805676 0.03382659845112574 2.0506814557971905e-07 6.688101795864543 -0.4145147624249156 APEPHVEEDDDDELDSK ddPTM_PC-9_AZD4547_30min_R2 2 APEPHVEEDDDDELDSK 17 0 F5H3P3;P52566;F5H2R5;F5H6Q0 F5H3P3 ARHGDIB Rho GDP-dissociation inhibitor 2 0 ; 279.19 4.849299999999999e-83 27856000.0 134810.0 179115.0 126770.0 95983.0 106714.0 159955.0 163250.0 167381.0 161964.0 115830.0 False True 177676.775777806 237010.42096526988 125088.94696995338 73855.60227256743 91898.60311772283 149952.98856383702 177778.93374284482 141516.11248273918 170525.08638394054 111774.82695590827 1.589595623779351 2.1204275365039322 1.1191155502239973 0.6607534476586682 0.8221762056851495 1.3415631466196665 1.5905095859640483 1.2660821433305633 1.5256126180468832 1.0 16.770235786812144 -5.272943654638598 24.769457713678754 1.166375780766854 1.8550115748417617 0.4594100679743127 0.29908287280704593 548.414175789917 1180772.7193676606 0.08659774277723946 0.18279798775311984 5.334040948400785e-06 5.272943654638598 0.6886357940749077 APEPHVEEDDDDELDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 APEPHVEEDDDDELDSK 17 0 F5H3P3;P52566;F5H2R5;F5H6Q0 F5H3P3 ARHGDIB Rho GDP-dissociation inhibitor 2 0 ;; 229.68 1.0658e-42 18958100.0 136573.0 258260.0 165753.0 154484.0 176619.0 89454.0 172295.0 100985.0 96083.0 92893.0 False True 159692.11146029388 283898.3460191202 169705.18014175261 145828.76232388566 142011.7748201003 84762.87476523303 155973.97029222213 98334.25075245195 97488.03210382246 109733.76555941645 1.455268673650199 2.587155781739765 1.546517421293303 1.3289324537480236 1.2941483789983186 0.7724411381776316 1.4213853821298827 0.8961166168968099 0.8884050556985269 1.0 16.74364799206206 -5.749575244577925 1.7964720803882264 1.048278070197886 2.027085209264424 0.577324842281866 0.32209444307078217 0.231155134702528 1.5180765729742878 0.09572679033845227 0.20098308227309242 1.7800194812232545e-06 5.749575244577925 0.978807139066538 APEPHVEEDDDDELDSK ddPTM_PC-9_Lapatinib_30min_R1 2 APEPHVEEDDDDELDSK 17 0 F5H3P3;P52566;F5H2R5;F5H6Q0 F5H3P3 ARHGDIB Rho GDP-dissociation inhibitor 2 0 ; 263.99 2.8753999999999993e-69 32134000.0 47739.0 158660.0 124145.0 134058.0 169874.0 151083.0 180613.0 192309.0 133324.0 144074.0 False True 47058.23310573962 158292.63251804162 113938.277313558 143917.07252437845 159882.34530513393 144621.5322816745 189964.25739380388 201244.37819852022 118307.64715603944 168976.9989334626 0.2784889860913529 0.9367702913245126 0.6742827605692241 0.851696227490986 0.946178156283212 0.8558651958224299 1.124201865300054 1.1909572277216465 0.7001405392613522 1.0 17.366467355364456 -4.5740997215064025 0.7074499464048338 0.9836670551766622 1.792915992727577e-24 0.5167965135513417 0.17173627264424912 3.383078234122707 1.0486874105549877 0.07090399971456474 2.84703390679387 2.6662463780563358e-05 4.5740997215064025 -0.9836670551766622 APEPPGSAS(ph)SSSQESLRPPAAALASR ddPTM_PC-9_AZD4547_30min_R2 1 APEPPGSASSSSQESLRPPAAALASR 26 1 Q9P227 Q9P227 ARHGAP23 Rho GTPase-activating protein 23 1 APEPPGS(0.076)AS(0.399)S(0.085)S(0.085)S(0.354)QES(0.001)LRPPAAALASR 56.766000000000005 0.01875 0.0 6601.9 9883.3 9422.7 10082.0 9643.4 9165.3 8134.0 13160.0 9383.3 8913.9 True False 8701.16687194938 13077.88344653463 9297.748841317194 7757.75066534725 8304.580367200637 8592.192342122082 8857.910242354063 11126.424386715602 9879.282081613379 8601.827074180002 1.0115486857516078 1.5203611202311136 1.0809039476306297 0.9018724276187317 0.9654437709086704 0.9988799202803272 1.0297707877600495 1.2934954737829654 1.1485097289700112 1.0 13.070427413185916 -5.491273769786035 24.956290299531698 1.0493954675529984 1.274624388746145 0.2403206588400928 0.152706126934642 852.5712661020228 673215.9660373378 0.04051444842120633 0.08420268188200003 3.2264595906377354e-06 5.491273769786035 0.22522892119314664 APEPQLS(ph)PGSDASEVR ddPTM_PC-9_AZD4547_30min_R2 2 APEPQLSPGSDASEVR 16 0 B4DKV7;Q8TE68-2;Q8TE68;K7ELW3;Q8TE68-4 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 APEPQLS(0.974)PGS(0.008)DAS(0.018)EVR;APEPQLS(0.999)PGS(0.001)DASEVR 187.04 5.2571e-08 48747000.0 25057.8 23324.0 25786.7 35337.0 28805.0 23720.6 23341.0 29003.0 30224.6 29359.0 True False 33025.65916538165 30863.026874320683 25444.751509269532 27190.600601207658 24805.92296049259 22237.347132176925 25418.303782491523 24521.25277263776 31822.210651256166 28331.15034618411 1.16570131328359 1.0893672334938418 0.8981192503076973 0.9597422013917599 0.8755706230556809 0.7849080203399523 0.8971857292026649 0.8655226657939252 1.123223387063853 1.0 14.790101561041029 -5.13253023921795 3.0592431888730554 0.9134113617584617 1.1578451362827504 0.46868216611022406 0.08668429053501166 0.21888310759799492 3.760479750281708 0.023012661922927953 0.08379287556983739 7.370038571722713e-06 5.13253023921795 0.24443377452428872 APEPQLS(ph)PGSDASEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 APEPQLSPGSDASEVR 16 0 B4DKV7;Q8TE68-2;Q8TE68;K7ELW3;Q8TE68-4 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 APEPQLS(0.993)PGS(0.007)DAS(0.001)EVR;APEPQLS(0.991)PGS(0.009)DASEVR;APEPQLS(0.953)PGS(0.008)DAS(0.038)EVR 134.93 1.0499e-05 34926000.0 25376.4 23830.0 31194.7 34958.2 30812.4 30008.4 31815.7 27972.9 30300.8 25827.4 True False 29672.12331325375 26195.684913016525 31938.499954558567 32999.605390013574 24774.93140866414 28434.706677230944 28801.88657027917 27238.64101473747 30743.891876518315 30509.703170414097 0.9725470991152557 0.8586017624196041 1.0468308975726124 1.081610175152867 0.8120344950680777 0.9319889649009985 0.9440238211890887 0.8927861691277074 1.007675876254716 1.0 14.896980523521911 -6.250488674974816 24.9976581928084 0.9267163427689235 0.9845858765677197 0.12475308584947764 0.07473992724923158 1712.1421041974895 3908380.0670544826 0.022733645901776484 0.029054539889823445 5.617089257551661e-07 6.250488674974816 0.057869533798796224 APEPQLS(ph)PGSDASEVR ddPTM_PC-9_Lapatinib_30min_R1 2 APEPQLSPGSDASEVR 16 0 B4DKV7;Q8TE68-2;Q8TE68;K7ELW3;Q8TE68-4 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 APEPQLS(0.998)PGS(0.002)DASEVR;APEPQLS(0.972)PGS(0.021)DAS(0.007)EVR 171.87 2.1581999999999998e-05 38790000.0 24786.4 26998.0 22810.7 23334.0 24432.0 20158.4 21232.7 17600.2 23225.0 18065.3 True False 24432.94139073094 26935.487789752187 20935.29229784835 25050.060199942134 22994.957795160135 19296.272223525542 22332.025313601003 18417.969544689015 20609.155929907713 21187.863034500835 1.1531574161559401 1.2712696766961502 0.9880794615180769 1.1822834685665264 1.0852891467967654 0.910722907359975 1.054000834215187 0.8692698038824623 0.9726868583372096 1.0 14.370950467259766 -6.360330394742721 0.8442200297582406 0.9464147564862176 1.1833372340158248 0.5144412025384811 0.08324524092867792 0.4908619544061066 0.7628443349948316 0.044336565447074094 0.0657009031400171 4.361838738651692e-07 6.360330394742721 0.23692247752960716 APES(ph)DTGDEDQDQERDTVFLK ddPTM_PC-9_Lapatinib_30min_R1 2 APESDTGDEDQDQERDTVFLK 21 1 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 APES(0.994)DT(0.006)GDEDQDQERDTVFLK;APES(0.829)DT(0.159)GDEDQDQERDT(0.012)VFLK 69.27 0.0014635 7919000.0 21627.4 23654.0 27641.0 23257.4 21723.7 21113.5 15790.7 15944.0 24291.0 19046.1 True False 21318.989310020574 23599.23061629743 25368.46367734556 24967.826780412048 20445.954676437475 20210.524822972387 16608.26518151151 16684.816446433648 21555.09178443007 22338.193007667007 0.954373941647983 1.056452086710756 1.1356542433239112 1.1177191804118842 0.9152913429219601 0.9047520010251343 0.7434918829742027 0.7469188058634383 0.9649433943484974 1.0 14.447224866878475 -6.472042804921329 2.8887247583477462 0.8489236300676815 1.0697136073852915 0.4983742873062471 0.09060537235997963 0.20822934451210048 3.4514856350819656 0.031501516152923674 0.034685820142054305 3.372540665942325e-07 6.472042804921329 0.22078997731761008 APES(ph)PPSADPALVAGPAEEAECPPPR ddPTM_PC-9_AZD4547_30min_R2 2 APESPPSADPALVAGPAEEAECPPPR 26 0 Q6EEV4-2;Q6EEV4 Q6EEV4-2 POLR2M DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5 1 APES(0.983)PPS(0.017)ADPALVAGPAEEAECPPPR;APES(0.888)PPS(0.112)ADPALVAGPAEEAECPPPR 148.61 2.3686e-12 3307400.0 9150.3 14343.0 15150.7 14309.6 12562.599999999999 13482.6 12707.5 16197.1 12761.8 11662.6 True False 12059.905061936477 18979.09425734787 14949.791818708474 11010.742801116146 10818.499836260518 12639.530890630456 13838.442882310586 13694.210367330657 13436.362694268932 11254.295923819158 1.0715823667309377 1.6863866372288614 1.3283631352777905 0.978359097330332 0.9612773566193245 1.1230849958263065 1.2296142713843352 1.2167984972162977 1.193887452864247 1.0 13.458188183210698 -5.598072633025491 6.57401010374658 1.111278986390272 1.4099496366479949 0.34060064233486353 0.16608601043048093 0.21071795409707134 14.625797612609416 0.04503054761385548 0.07876957785386543 2.5230587714539043e-06 5.598072633025491 0.298670650257723 APES(ph)PPSADPALVAGPAEEAECPPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APESPPSADPALVAGPAEEAECPPPR 26 0 Q6EEV4-2;Q6EEV4 Q6EEV4-2 POLR2M DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5 1 APES(0.876)PPS(0.124)ADPALVAGPAEEAECPPPR 104.32 6.0501e-10 2104000.0 4190.6 6776.9 7214.7 7180.3 8992.7 5581.8 7494.6 5494.8 3572.8 6130.6 True False 4899.985811877226 7449.665845028179 7386.725809902119 6778.011069846691 7230.644989637093 5289.0805818026865 6784.657231794818 5350.567322221844 3625.045440926465 7242.029250197105 0.6766039797124355 1.0286710516704172 1.0199801125770205 0.9359270496818574 0.9984280289174885 0.7303312923872455 0.9368447706297459 0.7388215564133793 0.5005565865158308 1.0 12.822178288461691 -7.282223648802557 1.2929382134506562 0.7347471395126759 0.9352921612960017 0.1395186006810053 0.1603184386044149 0.7383199312428088 2.398967862500324 0.10103782453827792 0.05731878810426232 5.2212723968173436e-08 7.282223648802557 0.20054502178332578 APES(ph)PPSADPALVAGPAEEAECPPPR ddPTM_PC-9_Lapatinib_30min_R1 3 APESPPSADPALVAGPAEEAECPPPR 26 0 Q6EEV4-2;Q6EEV4 Q6EEV4-2 POLR2M DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5 1 APES(0.878)PPS(0.122)ADPALVAGPAEEAECPPPR;APES(0.974)PPS(0.026)ADPALVAGPAEEAECPPPR;APES(0.97)PPS(0.03)ADPALVAGPAEEAECPPPR 158.8 1.9819000000000003e-11 2764100.0 3013.8599999999997 13800.699999999999 17932.3 13557.4 19331.5 18294.6 17158.8 18482.1 16341.3 15499.300000000001 True False 2970.8818037257647 13768.745327062477 16457.97551467978 14554.456422160609 18194.459177191307 17512.182604795547 18047.198705346796 19340.84583822325 14500.77071248228 18178.333353480935 0.1634298230732399 0.7574261654975056 0.9053621800553169 0.8006485599722817 1.000887090328734 0.9633546851775701 0.992786211717862 1.0639504437583496 0.7976952798978986 1.0 14.149932314346104 -4.777881490380018 2.3399523828159547 0.9430776475600767 4.119611905907782e-16 0.88988136445234 0.08210420896923068 0.18398417260121336 1.209097780366644 0.02201548357764047 0.36202835310048037 1.6677022305229383e-05 4.777881490380018 -0.9430776475600763 down APETDDSFS(ph)DVDCHSNQEDTGCK ddPTM_PC-9_Lapatinib_30min_R1 3 APETDDSFSDVDCHSNQEDTGCK 23 0 Q68D20 Q68D20 PMS2CL Protein PMS2CL 1 APET(0.005)DDS(0.292)FS(0.703)DVDCHSNQEDTGCK;APET(0.002)DDS(0.181)FS(0.817)DVDCHSNQEDTGCK;APET(0.004)DDS(0.216)FS(0.78)DVDCHSNQEDTGCK 112.34 4.9632999999999996e-06 10298400.0 12279.4 35773.6 35459.5 30868.9 44796.8 41742.0 43149.5 47477.0 41150.0 38944.0 True False 12104.293504233825 35690.76842712345 32544.156787628333 33139.1018816317 42161.940297897425 39956.79196535458 45383.56997787503 49682.95474330976 36515.25367128966 45675.41851038186 0.2650067344535127 0.7813999212511006 0.712509219378716 0.7255347178504626 0.9230772628457508 0.8747985955787695 0.9936103807688046 1.0877394529404696 0.7994508832576953 1.0 15.479130327451722 -4.687961758224599 0.597681548626822 0.9654597407421727 5.525350221017994e-16 0.7346227280363539 0.11264252585448585 2.212149615440512 0.5536758210276476 0.05647405333450215 1.5152368864305692 2.0513428017444416e-05 4.687961758224599 -0.9654597407421721 down APFDLFENR ddPTM_PC-9_AZD4547_30min_R2 2 APFDLFENR 9 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ; 109.48 0.010901000000000001 11574200.0 26926.0 27003.0 28403.0 32286.0 33673.0 27661.0 26042.0 34569.0 36187.0 31295.0 False True 35487.90790440768 35731.19167755452 28026.357661809474 24842.96151372755 28998.085188289086 25931.353297266764 28359.68754996121 29227.155366593615 38099.77094277529 30199.37157545665 1.1751207410305544 1.1831766627420035 0.9280443995923011 0.8226317376060133 0.9602214773189565 0.8586719505892451 0.9390820427869244 0.9678067404007451 1.2616080717964138 1.0 14.882230908093007 -5.25756919605614 23.9399613134207 0.9558076105669016 1.179148753108064 0.3636231956285346 0.11130341255893965 185.9556740989818 1150250.6830113344 0.02944049826344882 0.07187441193126319 5.526253512388355e-06 5.25756919605614 0.22334114254116244 APFDLFENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APFDLFENR 9 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 90.709 0.024944 0.0 3030.6 5085.9 6107.6 5516.2 5679.6 5229.3 6028.4 5171.2 3326.0 3799.8 False True 3543.6207229215674 5590.794540457851 6253.22834720199 5207.145197761695 4566.723151349744 4955.066302343475 5457.346310163567 5035.461479339302 3374.6364578261923 4488.673660799753 0.7894583101169792 1.245533750711949 1.3931127142996278 1.1600632149395176 1.0173880964507642 1.1039043327245637 1.2158037590977877 1.121815008142545 0.7518114955197989 1.0 12.132073496740905 -8.182100937565892 7.394872055814959 0.8773618073119703 1.1434132430181734 0.2898824601059835 0.15878648555588964 0.30670418633678265 24.824362590336456 0.10991007188708601 0.040973937476481904 6.575050040350639e-09 8.182100937565892 0.26605143570620304 APFDLFENR ddPTM_PC-9_Lapatinib_30min_R1 2 APFDLFENR 9 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ; 150.36 0.0010101 14296500.0 16312.5 20982.0 18619.7 17084.8 20002.2 19193.7 20175.1 18873.8 18680.8 18232.2 False True 16079.880758653877 20933.417468130232 17088.860140120505 18341.273185222046 18825.709921838235 18372.830193700018 21219.667960477556 19750.7456501944 16576.77158645513 21383.611477120583 0.7519721715790881 0.9789467738191916 0.7991568757412539 0.8577257029218993 0.880380282908751 0.8592014596485746 0.9923332166403024 0.9236393801545979 0.7752091644665103 1.0 14.384217909882272 -7.092021686985015 24.999999959590536 0.9177660307717785 0.8589898900465828 0.14901043540224745 0.07909566142589174 137.67217744041585 37395.29068313578 0.029075087024824014 0.022521470946383536 8.090554970704385e-08 7.092021686985015 -0.05877614072519577 APGAPPRS(ph)PPQR ddPTM_PC-9_AZD4547_30min_R2 2 APGAPPRSPPQR 12 1 H3BN50;Q15599-3 H3BN50 SLC9A3R2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 1 APGAPPRS(1)PPQR;APGAPPRS(1)PPQR 108.23 0.00703 21088800.0 40106.0 37323.0 57879.0 77930.0 69447.0 57897.0 49270.0 64100.0 49218.0 54685.0 True False 52858.87374337721 49386.92985895518 57111.48664253321 59964.442506497784 59805.48279247804 54276.69143746985 53654.93455136278 54194.81787146429 51819.562999461574 52770.49479481858 1.0016747796074732 0.9358815006563929 1.0822617234231593 1.1363251896661306 1.133312905725307 1.028542401364771 1.0167601186985846 1.0269908986486433 0.9819798582701488 1.0 15.687443890362731 -10.091597124418561 11.02552027054342 0.9999999463617177 1.0409194960695536 0.033158772975670714 0.0602709310115142 0.0 0.0 0.06528024092040743 0.015832784034153422 8.098468095231942e-11 10.091597124418561 0.040919549707835845 APGAPPRS(ph)PPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 APGAPPRSPPQR 12 1 H3BN50;Q15599-3 H3BN50 SLC9A3R2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 1 APGAPPRS(1)PPQR;APGAPPRS(1)PPQR;APGAPPRS(1)PPQR;APGAPPRS(1)PPQR 61.657 0.025908999999999998 75851700.0 62551.9 63172.8 82641.0 72874.1 94021.0 81231.0 82912.0 88410.0 82835.0 63952.2 True False 73140.70121365975 69444.17808950943 84611.47485773772 68791.2004380198 75598.25998539572 76971.10336099724 75057.97512910268 86089.3311781382 84046.3051665763 75546.22761466332 0.9681582194510971 0.9192276078128154 1.119996027985848 0.9105841894435985 1.0006887487618548 1.0188609781232458 0.993537036845161 1.1395583061705188 1.1125149172936748 1.0 16.205072096058046 -7.743533267946688 24.13382128042752 1.0945274298489431 0.9908659581504882 0.3074009440529123 0.06398557877757383 165.60764260787303 223206.30067078513 0.029170666206802427 0.016790363897890185 1.804956468058415e-08 7.743533267946688 -0.10366147169845497 APGAPPRS(ph)PPQR ddPTM_PC-9_Lapatinib_30min_R1 2 APGAPPRSPPQR 12 1 H3BN50;Q15599-3 H3BN50 SLC9A3R2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 1 APGAPPRS(1)PPQR;APGAPPRS(1)PPQR 105.95 0.0083472 18756000.0 52867.0 49065.0 48752.0 48703.0 57507.0 50756.0 36723.0 40555.0 61201.0 46669.0 True False 52113.10688537959 48951.39300704459 44743.79874816216 52284.78108844524 54124.55132311204 48585.28419801487 38624.33725298098 42439.333353306385 54307.89890489911 54735.674467466335 0.952086685555587 0.8943233728880094 0.8174522225857813 0.9552231080941945 0.9888350120775888 0.8876347038875512 0.705651983441593 0.7753505143803677 0.9921847028153187 1.0 15.740193808572625 -7.006906180829783 24.85181318855614 0.8420142027170539 0.9183614846351454 0.03886756193716001 0.0942192071430198 659.4673361904955 2373091.6800630298 0.03445519874458581 0.02927229874567951 9.842237013194116e-08 7.006906180829783 0.07634728191809159 APGAS(ph)PGNPLSPSLSDKDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APGASPGNPLSPSLSDKDR 19 1 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 APGAS(1)PGNPLSPSLSDKDR 67.29899999999999 0.004368199999999999 3327100.0 12628.0 10679.0 17511.0 15351.0 17614.0 13332.0 15301.0 14709.0 14969.0 10637.0 True False 14765.670985631086 11739.140544947682 17928.52865083731 14490.933238613488 14162.66314315697 12632.846450355339 13851.57851035311 14322.904335473733 15187.893306434244 12565.403897554324 1.1751051622387572 0.9342429929556453 1.4268167419852569 1.1532405449723697 1.127115631031449 1.005367320728476 1.102358397969931 1.139868200994437 1.2087071319203953 1.0 13.617169424952936 -6.320975915017036 4.111132847018021 1.098380731627728 1.1737684010615463 0.08358082317067583 0.12423483693628638 0.6837488345598791 23.627988959671285 0.03995359947185693 0.04663641429175453 4.775557570780968e-07 6.320975915017036 0.07538766943381825 APGASPGNPLS(ph)PSLSDKDR ddPTM_PC-9_AZD4547_30min_R2 4 APGASPGNPLSPSLSDKDR 19 1 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 APGASPGNPLS(0.952)PS(0.039)LS(0.009)DKDR;APGASPGNPLS(0.98)PS(0.016)LS(0.004)DKDR;APGASPGNPLS(0.829)PS(0.14)LS(0.031)DKDR;APGASPGNPLS(0.982)PS(0.015)LS(0.003)DKDR 99.414 0.00023654 58924900.0 102305.0 117557.0 136050.0 190971.0 178666.0 160176.0 136128.0 174992.0 150007.0 143968.0 True False 134835.86192380727 155555.00129756972 134245.88810650923 146945.586422538 153861.30989964862 150160.16939890076 148243.1282851206 147951.00731612017 157936.06377463992 138927.72414044887 0.9705468275539809 1.1196829305309248 0.9663002034841761 1.0577124712270063 1.1074917612851891 1.0808509988049357 1.067052161131311 1.064949478093726 1.136821788104544 1.0 17.083975003840813 -5.993555534749517 24.989902345492055 1.0795252506841562 1.0261071200544882 0.19530227885977414 0.05116572955441375 268.1299687593669 1039723.300612386 0.013477998157228171 0.019937351881964126 1.01494957313388e-06 5.993555534749517 -0.05341813062966794 APGASPGNPLS(ph)PSLSDKDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 APGASPGNPLSPSLSDKDR 19 1 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 APGASPGNPLS(0.985)PS(0.01)LS(0.005)DKDR;APGASPGNPLS(0.965)PS(0.026)LS(0.008)DKDR;APGASPGNPLS(0.984)PS(0.008)LS(0.008)DKDR;APGASPGNPLS(0.982)PS(0.012)LS(0.006)DKDR 78.717 0.0014219 38766000.0 118318.0 102214.0 112279.0 127194.0 186040.0 152214.0 163998.0 156739.0 158934.0 129076.0 True False 138346.90051297884 112361.13041120753 114956.15718047848 120067.732548512 149586.79749931462 144231.6298825674 148462.92219730015 152624.76732869798 161258.10907641237 152476.4570349461 0.9073328643862121 0.7369080617177213 0.753927258121768 0.7874509605177517 0.9810484871446796 0.9459272118941675 0.9736776751264224 1.0009726766783273 1.0575934948400172 1.0 17.21822697651571 -6.2707013265125 5.987292276753348 0.990593858913765 0.7885078788244342 0.7876803467326695 0.04998943084078603 0.0720171344091113 11.235682814006164 0.015663368386279526 0.01873471406207556 5.361652629250695e-07 6.2707013265125 -0.20208598008933076 APGASPGNPLS(ph)PSLSDKDR ddPTM_PC-9_Lapatinib_30min_R1 3 APGASPGNPLSPSLSDKDR 19 1 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 APGASPGNPLS(0.971)PS(0.024)LS(0.005)DKDR;APGASPGNPLS(0.854)PS(0.081)LS(0.065)DKDR;APGASPGNPLS(0.981)PS(0.019)LS(0.001)DKDR 97.509 0.00028383 50790300.0 144772.0 120134.0 126774.0 105437.0 172548.0 172153.0 172077.0 147735.0 159675.0 145597.0 True False 142707.52473206675 119855.83710401083 116351.1310817916 113191.18870752107 162399.0658824201 164790.41749824348 180986.30508077244 154599.30743313336 141690.72004770784 170763.24745419252 0.8357039752968405 0.7018830977442164 0.6813593253607041 0.6628545099429827 0.951018842189587 0.9650227432132241 1.0598668494479309 0.9053429806352497 0.8297495050023371 1.0 17.38163797854581 -6.269998116670824 24.28741420975127 0.953161785218261 0.7163317952867048 0.7206255456776792 0.07055754730044993 233.84658101636816 663593.0061610475 0.022889067239502413 0.026382591762621893 5.37034125227481e-07 6.269998116670824 -0.23682998993155624 APGASPGNPLSPS(ph)LSDKDR ddPTM_PC-9_Lapatinib_30min_R1 1 APGASPGNPLSPSLSDKDR 19 1 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 APGASPGNPLS(0.332)PS(0.466)LS(0.201)DKDR 75.3 0.0019255 12418000.0 26489.0 24114.0 22084.0 23137.0 27356.0 32249.0 31014.0 29037.0 32980.0 29580.0 True False 26111.26200251234 24058.165514559743 20268.33876670522 24838.57216276942 25746.97386396533 30869.785446090744 32619.753167332525 30386.16502478009 29265.445105203737 34692.863587127526 0.7526407249991519 0.6934615084206053 0.5842221330563674 0.7159562398298406 0.7421403482391841 0.8898021741146989 0.94024389440818 0.875862119264626 0.8435580715816845 1.0 15.082351306724423 -6.659636489356544 2.4393745305281462 0.9077923662504067 0.6808112820902187 0.7897706680147141 0.0553649042886944 0.13497280735860892 1.6379837755330997 0.02095710896070469 0.020629727145926244 2.1895935780492717e-07 6.659636489356544 -0.22698108416018803 APGFGDNRK ddPTM_PC-9_AZD4547_30min_R2 1 APGFGDNRK 9 1 P10809 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 66.29899999999999 0.030891000000000002 22678000.0 66773.0 70988.0 87097.0 115200.0 93287.0 90084.0 89947.0 122990.0 68385.0 88336.0 False True 88005.42503531951 93933.48275399912 85942.03687183114 88642.4198222577 80335.7103008322 84451.03323925303 97952.10874957219 103984.72152903884 71999.69148925545 85243.38352738565 1.032401828665641 1.101944560000034 1.0081959832603433 1.0398744882502235 0.9424275172632397 0.9907048470468318 1.1490875267533658 1.2198568056092267 0.8446367156006251 1.0 16.379300238053702 APGPPYS(ph)PVPAESESLVNGNHTPQTATR ddPTM_PC-9_AZD4547_30min_R2 2 APGPPYSPVPAESESLVNGNHTPQTATR 28 0 Q86UU1-3;Q86UU1-2;Q86UU1;A0A087WXY7;A0A087WTZ7 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 APGPPY(0.043)S(0.913)PVPAES(0.032)ES(0.011)LVNGNHTPQTATR;APGPPY(0.452)S(0.528)PVPAES(0.017)ES(0.003)LVNGNHTPQTATR 60.196999999999996 0.00091928 25320000.0 8847.6 9916.4 16890.5 27031.5 21183.3 18631.8 13311.7 19574.3 18673.1 16528.2 True False 11660.952758487607 13121.682374228847 16666.520933943346 20799.805307511826 18242.364445374176 17466.75060062957 14496.415511820089 16549.541707666216 19660.121944110804 15949.552748792534 0.7311147178951712 0.8226990800868839 1.0449522438931769 1.3040995967166842 1.1437539806095955 1.095124789750101 0.9088916623644852 1.0376179174628646 1.232644090637537 1.0 13.96122834860882 -5.236956912415129 3.2902627683747347 1.1025805665070045 0.7541336177779052 0.5971126870782968 0.10649310250097946 0.1751223221676597 3.908772550981132 0.03041615238260508 0.08985188626642363 5.7948618603980025e-06 5.236956912415129 -0.3484469487290993 APGPPYS(ph)PVPAESESLVNGNHTPQTATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APGPPYSPVPAESESLVNGNHTPQTATR 28 0 Q86UU1-3;Q86UU1-2;Q86UU1;A0A087WXY7;A0A087WTZ7 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 APGPPY(0.06)S(0.841)PVPAES(0.097)ES(0.002)LVNGNHTPQTATR 88.027 1.7697e-07 7756600.0 2853.8 2599.9 8364.1 8728.2 10504.0 15830.0 15892.0 14551.0 9405.5 10273.0 True False 3336.8919748807407 2858.0008898594897 8563.531865025896 8239.187251206198 8445.816603594914 14999.84693287767 14386.594711883647 14169.0516680589 9543.037644042175 12135.413578976739 0.27497142583269985 0.2355091461250781 0.7056646079093066 0.6789374913006408 0.695964463726754 1.2360392033826721 1.1855051019280323 1.1675788036268673 0.7863792677469544 1.0 13.566935656408608 -5.728767991094374 0.8263407754342863 1.0822258748639195 0.16180479852200416 0.767331110887361 0.16304942436796038 0.41776685933058916 0.5009202487701295 0.07691513698122451 0.27651954975050663 1.8673770150267733e-06 5.728767991094374 -0.9204210763419154 down APGPPYS(ph)PVPAESESLVNGNHTPQTATR ddPTM_PC-9_Lapatinib_30min_R1 1 APGPPYSPVPAESESLVNGNHTPQTATR 28 0 Q86UU1-3;Q86UU1-2;Q86UU1;A0A087WXY7;A0A087WTZ7 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 APGPPY(0.009)S(0.99)PVPAES(0.001)ESLVNGNHTPQTATR 98.991 5.982500000000001e-10 8893900.0 2551.1 2863.7 5955.8 2298.4 7244.9 8422.9 5156.8 7304.4 8738.5 7810.0 True False 2514.720846185556 2857.069278595202 5466.137114052847 2467.432003237636 6818.769226021432 8062.672201738892 5423.793871583815 7643.789090023209 7754.2781095155515 9159.948093829142 0.2745343991501075 0.3119088939510419 0.596743241125489 0.26937183245611307 0.7444113390353259 0.8802093766416142 0.5921205902070239 0.8344795201593624 0.8465417085430256 1.0 13.161123707767334 -5.771536235551878 0.3208696339101312 0.9776626526415914 1.8168847366190544e-13 0.7362486884854925 0.1320551991412073 2.057038773525885 0.27798999053720874 0.1549639150374723 0.7481608975438993 1.692247045166495e-06 5.771536235551878 -0.9776626526414096 down APGPPYSPVPAES(ph)ESLVNGNHTPQTATR ddPTM_PC-9_Lapatinib_30min_R1 1 APGPPYSPVPAESESLVNGNHTPQTATR 28 0 Q86UU1-3;Q86UU1-2;Q86UU1;A0A087WXY7;A0A087WTZ7 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 APGPPY(0.034)S(0.462)PVPAES(0.486)ES(0.018)LVNGNHTPQTATR 77.40100000000001 1.25e-05 7554500.0 8821.9 8276.8 10125.0 8283.4 13876.0 15621.0 15704.0 15448.0 20894.0 11746.0 True False 8696.09808826168 8257.635578125077 9292.561583630248 8892.58886861235 13059.840961265632 14952.926244329537 16517.076279737867 16165.770475696634 18540.69769642592 13776.280449438815 0.6312370106123908 0.5994096598448282 0.6745334212478802 0.6454999882769225 0.9479947079472844 1.0854109931348452 1.198950350957083 1.1734495777018794 1.3458420627014156 1.0 13.74989879723542 -6.510859384287963 1.5508554285569576 1.1937284830287804 0.6203775560554419 0.8993133390193 0.08266288402306435 0.1036473277147394 0.5078037648915456 0.031372570935027495 0.03489678699767773 3.084186385369027e-07 6.510859384287963 -0.5733509269733386 APGPS(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APGPSPAK 8 0 Q9H9J4-2;Q9H9J4;C9JPC9 Q9H9J4-2 USP42 Ubiquitin carboxyl-terminal hydrolase 42 1 APGPS(1)PAK 70.399 0.038245 9708100.0 39789.0 63595.0 44163.0 46240.0 53760.0 41040.0 42954.0 45258.0 29014.0 27723.0 True False 46524.49183142816 69908.2913152868 45216.013409110165 43649.32271210269 43226.11391938909 38887.79015320907 38885.08615997045 44070.02545481481 29438.274860904745 32748.96044485276 1.4206402645901555 2.1346720740344742 1.3806854567262115 1.332846054323021 1.3199232382407746 1.1874511320349763 1.1873685647350716 1.3456923473655302 0.8989071549454827 1.0 14.999161491242011 -5.470011060647791 5.241854245455131 1.2114052526732455 1.7817470344181114 0.5520180746209222 0.21093494395503995 0.140953208435616 8.502530646844741 0.05280280442180131 0.10988703000908075 3.3883552653809402e-06 5.470011060647791 0.5703417817448659 APGPS(ph)PAKEK ddPTM_PC-9_AZD4547_30min_R2 1 APGPSPAKEK 10 1 Q9H9J4-2;Q9H9J4;C9JPC9 Q9H9J4-2 USP42 Ubiquitin carboxyl-terminal hydrolase 42 1 APGPS(1)PAKEK 59.155 0.034816 6117000.0 30112.0 25358.0 32292.0 40803.0 35749.0 36857.0 32021.0 31672.0 31488.0 34361.0 True False 39686.989631490884 33554.47759728279 31863.78698078201 31396.49875006583 30785.868422657506 34552.32596353572 34870.806967103454 26777.820150156298 33152.39139597394 33158.03184867442 1.1969042617671977 1.0119562509143383 0.9609673796744317 0.9468746182931539 0.9284588591734599 1.042049966090404 1.0516549090201053 0.8075817127012866 0.9998298918124505 1.0 15.017070755308763 -4.743028731686547 2.619728807774367 0.9641417387670378 1.2588822241274 0.5262576946358202 0.06513373782951773 0.45069969886064465 3.697446597741846 0.01708845321021544 0.30895629209244513 1.8070545724702283e-05 4.743028731686547 0.29474048536036224 APGS(ph)PAAPR ddPTM_PC-9_AZD4547_30min_R2 4 APGSPAAPR 9 0 Q5SPY9;Q9NQX5 Q5SPY9 NPDC1 Neural proliferation differentiation and control protein 1 1 APGS(1)PAAPR;APGS(1)PAAPR;APGS(1)PAAPR;APGS(1)PAAPR 89.679 0.0091598 17274700.0 10054.3 18282.0 24750.5 41449.9 29330.1 19124.9 19977.9 28232.4 20130.699999999997 20099.800000000003 True False 13251.358257568369 24191.298976004564 24422.292198310588 31894.265949571196 25258.121889378388 17929.016979678858 21755.894397679534 23869.731296011385 21194.767704361417 19396.112119902977 0.6831966208305592 1.2472241254566214 1.2591333792739878 1.6443638679961774 1.3022260200001738 0.9243613807161547 1.1216626436880157 1.2306451493192743 1.092732789609562 1.0 14.243479877969463 -6.729292320620376 24.99080266855691 1.0912818527211594 1.25328634168977 0.091193705155446 0.23172227297999934 502.49701814047694 390634.89272660716 0.08043489883713087 0.08042876009590766 1.86512386622832e-07 6.729292320620376 0.16200448896861053 APGS(ph)PAAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 APGSPAAPR 9 0 Q5SPY9;Q9NQX5 Q5SPY9 NPDC1 Neural proliferation differentiation and control protein 1 1 APGS(1)PAAPR;APGS(1)PAAPR;APGS(1)PAAPR;APGS(1)PAAPR 96.171 0.0051903999999999995 16945100.0 11591.3 18519.4 29001.1 12961.399999999998 32163.800000000003 23016.100000000002 13181.900000000001 16163.1 25019.1 8778.900000000001 True False 13553.478151389414 20357.883641549215 29692.59621128423 12235.21477942577 25861.534279770214 21809.095198471612 11933.215003308522 15738.835751220055 25384.957006013003 10370.445076265845 1.306933121164526 1.9630674953518594 2.86319400883186 1.1798157831651508 2.493772840951427 2.1030047445489735 1.150694585965195 1.5176625145279918 2.447817506319944 1.0 13.34019019226784 -7.227423835199991 24.873281478382413 1.57218196590292 2.010418868189807 0.1244123396358513 0.5857660335648852 1330.618323349001 972992.8951223353 0.22020103344171374 0.1705578420339122 5.923469611683798e-08 7.227423835199991 0.4382369022868873 APGS(ph)PAAPR ddPTM_PC-9_Lapatinib_30min_R1 4 APGSPAAPR 9 0 Q5SPY9;Q9NQX5 Q5SPY9 NPDC1 Neural proliferation differentiation and control protein 1 1 APGS(1)PAAPR;APGS(1)PAAPR;APGS(1)PAAPR;APGS(1)PAAPR 89.82700000000001 0.0090455 16552800.0 25537.3 25269.5 20593.5 12537.5 20253.9 15801.5 13866.4 11194.9 21921.9 7090.400000000001 True False 25173.133419032732 25210.990025303443 18900.381923208846 13459.54957387394 19062.60542269949 15125.70668009559 14584.33434318372 11715.05592299173 19452.82477415906 8315.966192635875 3.027084626838017 3.0316369068008955 2.272782438671516 1.6185190346003229 2.29228991329717 1.8188754414959043 1.753775088227119 1.4087426104937617 2.3392140279965696 1.0 13.021668177801166 -1.5228787453197072 0.294580209717185 1.4877987514807403 15.840273233639355 0.6561175871500009 0.3686001353244408 32.3289071901655 0.45978491159576373 0.37646308684770247 242.98724448524317 0.029999999997280438 1.5228787453197072 14.352474482158614 APGS(ph)SSCGAER ddPTM_PC-9_AZD4547_30min_R2 1 APGSSSCGAER 11 0 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 APGS(0.905)S(0.048)S(0.048)CGAER 73.082 0.025626999999999997 3374000.0 5880.8 5281.0 6207.7 9128.4 4437.8 6940.7 5768.8 6375.2 5801.7 5326.2 True False 7750.772071761144 6987.979974416371 6125.381841960873 7023.988412374114 3821.6880720039585 6506.696931793476 6282.212024353594 5390.0593275219835 6108.366017594705 5139.731359169109 1.5080111255102906 1.3596002370727116 1.1917708171718735 1.3666061359108883 0.7435579420286617 1.2659605098203714 1.2222841205788582 1.048704484896141 1.1884601724752761 1.0 12.327477240010637 -5.032505964548222 0.9836514140093909 1.1077558707122939 1.617536957965934 0.4141478015252633 0.15747276215565953 1.4228092034388644 1.4491173198143437 0.0536420585849034 0.7052622980953963 9.278847465822232e-06 5.032505964548222 0.5097810872536401 APGYPS(ph)SPVTTASGTTLR ddPTM_PC-9_AZD4547_30min_R2 1 APGYPSSPVTTASGTTLR 18 0 H0YJG4;Q9HCK8-2;Q9HCK8;H0YJA4 H0YJG4 CHD8 Chromodomain-helicase-DNA-binding protein 8 1 APGYPS(0.943)S(0.051)PVT(0.004)T(0.002)ASGTTLR 247.02 1.5967e-53 54227000.0 13752.0 13400.0 15780.0 28189.0 20214.0 19830.0 18513.0 17870.0 11352.0 14589.0 True False 18124.849940630414 17731.287948717934 15570.746889531172 21690.461565708538 17407.635019038273 18590.026965214558 20160.621135566846 15108.602111748316 11952.043544432683 14078.243550546007 1.2874368791501312 1.2594815457664283 1.106014882725003 1.5407079361734228 1.2364919641103338 1.3204791420513227 1.4320409405607237 1.0731880051302527 0.8489726365025939 1.0 13.78117972922162 -7.954310834310813 4.994232952952351 0.9328253153235038 1.3070960174625825 0.6595473218650527 0.11433757608567355 0.11071860818438663 6.192766971929895 0.06685582671876163 0.029978891162417233 1.1109363206046398e-08 7.954310834310813 0.37427070213907876 APGYPS(ph)SPVTTASGTTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APGYPSSPVTTASGTTLR 18 0 H0YJG4;Q9HCK8-2;Q9HCK8;H0YJA4 H0YJG4 CHD8 Chromodomain-helicase-DNA-binding protein 8 1 APGYPS(0.885)S(0.112)PVT(0.003)TASGTTLR 155.63 1.5482000000000002e-05 5857600.0 4517.5 5831.4 5953.9 4654.6 6136.1 7516.5 7042.4 5649.4 5380.2 5405.6 True False 5282.223525307916 6410.302853619996 6095.863556291492 4393.817852416809 4933.7752533624125 7122.321507957993 6375.292889439306 5501.1092360340845 5458.875246661601 6385.592489293948 0.8272096182404476 1.0038697058052917 0.9546277133268034 0.688083033764441 0.7726417339713354 1.1153736352420298 0.9983870565069866 0.861487676399209 0.8548737264104972 1.0 12.640604771733289 -6.730903818878022 24.999711352997082 0.9593904157751179 0.8547709338485783 0.22586400651075 0.10747136736839268 396.4295559754931 324559.1220838821 0.039179023784664306 0.03917462210763189 1.8582159397228634e-07 6.730903818878022 -0.10461948192653958 APGYPSS(ph)PVTTASGTTLR ddPTM_PC-9_AZD4547_30min_R2 1 APGYPSSPVTTASGTTLR 18 0 H0YJG4;Q9HCK8-2;Q9HCK8;H0YJA4 H0YJG4 CHD8 Chromodomain-helicase-DNA-binding protein 8 1 APGYPS(0.039)S(0.937)PVT(0.021)T(0.002)ASGTTLR 228.99 3.521199999999999e-35 54694000.0 20587.0 19923.0 25570.0 42575.0 31051.0 22612.0 14806.0 29816.0 17195.0 20339.0 True False 27133.237763798592 26362.720134500556 25230.925092858797 32759.99152719295 26740.104629274618 21198.068065427713 16123.705316977417 25208.622303519187 18103.89259571175 19626.937800709777 1.382448858772934 1.3431906903759174 1.2855252994150907 1.6691341186197797 1.3624185749601552 1.0800496888852993 0.8215089628701187 1.2843889637540686 0.9224002633287528 1.0 14.260547480303257 -6.765271373947959 4.262384062711766 1.0216519979541756 1.4167721000037834 0.6456332104938243 0.14424102779914902 0.13451909748211566 5.700924856013452 0.0506766546498705 0.04723313538963159 1.7168352674723332e-07 6.765271373947959 0.3951201020496078 APGYPSS(ph)PVTTASGTTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APGYPSSPVTTASGTTLR 18 0 H0YJG4;Q9HCK8-2;Q9HCK8;H0YJA4 H0YJG4 CHD8 Chromodomain-helicase-DNA-binding protein 8 1 APGYPS(0.01)S(0.888)PVT(0.091)T(0.011)ASGTTLR;APGYPS(0.055)S(0.605)PVT(0.26)T(0.079)ASGTTLR 216.71 1.5325999999999998e-27 72866000.0 42099.0 35228.0 49119.0 33120.0 48941.0 47917.0 54349.0 50534.0 35207.0 28063.0 True False 49225.52920684852 38725.20302625872 50290.18324484484 31264.39377648877 39351.36237590812 45404.148166942476 49200.66926731467 49207.53604519886 35721.83576989981 33150.59975341422 1.4849061426642431 1.168159952287752 1.5170218221969087 0.9431019049140675 1.1870482787224768 1.3696327820514391 1.4841562334704799 1.4843633723438416 1.0775622774734497 1.0 15.016747351047172 -8.435841727580774 5.969193687057394 1.0013863194222847 1.318843944047966 0.3099157304083031 0.17483841917189138 0.2664916057459839 13.468998611560115 0.173077773612363 0.04487796353639368 3.6657114192353624e-09 8.435841727580774 0.3174576246256813 APGYPSS(ph)PVTTASGTTLR ddPTM_PC-9_Lapatinib_30min_R1 2 APGYPSSPVTTASGTTLR 18 0 H0YJG4;Q9HCK8-2;Q9HCK8;H0YJA4 H0YJG4 CHD8 Chromodomain-helicase-DNA-binding protein 8 1 APGYPS(0.041)S(0.957)PVT(0.001)TASGTTLR;APGYPS(0.123)S(0.874)PVT(0.001)T(0.001)ASGTTLR 177.66 1.6281000000000002e-08 99969000.0 96449.0 76066.0 104468.0 83707.0 95927.0 96642.0 85493.0 93540.0 106461.0 76134.0 True False 95073.61957341967 75889.87385048128 95879.0442981416 89863.09201836627 90284.76245973841 92508.84694350533 89919.40921953836 97886.2098845588 94470.2410959702 89293.66045782155 1.0647297813300902 0.8498909492721307 1.073749735496964 1.00637706593755 1.0110993546107903 1.0360068841303969 1.0070077624604983 1.096227989564791 1.0579725437573908 1.0 16.44627013215549 -5.310183795617865 24.999862344106386 1.036501538791215 0.9573093834311867 0.23523707721064513 0.05678804135643697 442.97673011009203 227191.51078549415 0.01392710957529744 0.028991717908041597 4.895715863529002e-06 5.310183795617865 -0.07919215536002844 APIDT(ph)SDVEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APIDTSDVEEK 11 0 D6RIY6;Q06265-3;Q06265-4;Q06265;Q06265-2 D6RIY6 EXOSC9 Exosome complex component RRP45 1 APIDT(0.5)S(0.5)DVEEK 93.345 0.017488 9038200.0 24154.0 50794.0 34451.0 31593.0 31777.0 22333.0 35614.0 19578.0 20952.0 24689.0 True False 28242.7951367543 55836.492634148584 35272.44249614505 29822.946635887954 25550.52496310317 21161.81816500044 32240.384096968573 19064.09824460568 21258.38336271029 29164.920261983538 0.9683823882614475 1.9145086676932024 1.2094133012982267 1.0225622552022593 0.876070454970805 0.725591497419071 1.105450788390939 0.6536653648752033 0.7289025024498553 1.0 14.831946509322654 -5.75347403661819 2.415100343499313 0.8449519248398862 1.4578484975358956 0.46370330007153415 0.2507844536515304 0.2224353029413595 2.6447204069787245 0.07061811371802451 0.13135249060320364 1.7641112250017692e-06 5.75347403661819 0.6128965726960094 APIDTS(ph)DVEEK ddPTM_PC-9_AZD4547_30min_R2 4 APIDTSDVEEK 11 0 D6RIY6;Q06265-3;Q06265-4;Q06265;Q06265-2 D6RIY6 EXOSC9 Exosome complex component RRP45 1 APIDT(0.007)S(0.993)DVEEK;APIDT(0.058)S(0.942)DVEEK;APIDT(0.032)S(0.968)DVEEK;APIDT(0.05)S(0.95)DVEEK 164.48 0.00013014 50453200.0 104931.0 105928.0 89267.0 60900.7 77385.0 125042.0 126304.0 124083.0 125120.0 83956.0 True False 138296.87529961352 140167.15446505926 88083.26125397834 46860.984521435515 66641.42851233194 117223.10397298844 137544.81131673057 104908.8234936804 131733.58776245726 81016.7259942174 1.7070163426436722 1.730101441954884 1.0872231650074988 0.5784112347958894 0.8225638310425986 1.4469000386581319 1.6977335189593799 1.2949032709760242 1.6260048298157568 1.0 16.30593216431035 -6.922311931500219 24.999992034723736 1.4497199772287204 1.1720554600504558 0.08053993007340288 0.3739192805379127 87.67786905362908 28210.50112211961 0.14669752132958666 0.12937504286712911 1.195881282444048e-07 6.922311931500219 -0.27766451717826457 APIDTS(ph)DVEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APIDTSDVEEK 11 0 D6RIY6;Q06265-3;Q06265-4;Q06265;Q06265-2 D6RIY6 EXOSC9 Exosome complex component RRP45 1 APIDT(0.161)S(0.839)DVEEK;APIDT(0.225)S(0.775)DVEEK 155.88 0.00069335 17577300.0 62514.0 115240.0 76449.0 70087.0 75396.0 52213.0 77318.0 43279.0 51762.0 54677.0 True False 73096.38549221892 126680.2656053721 78271.83409444708 66160.25261511991 60622.69503471457 49474.85836426666 69993.87930615518 42142.97210789096 52518.92132591686 64589.50727710613 1.1317068139042465 1.9613133920015853 1.2118351322706356 1.0243188933347156 0.9385842622181203 0.7659890971455532 1.0836726003476518 0.652473968056242 0.8131184698560519 1.0 15.979012194177566 -5.65148233728779 2.5800957311533677 0.8759264512853701 1.554059106370065 0.5704714007619242 0.2245758705737492 0.1739124237056757 2.3322354683287383 0.06114074003384291 0.12191036105698214 2.231092943958915e-06 5.65148233728779 0.678132655084695 APIDTS(ph)DVEEK ddPTM_PC-9_Lapatinib_30min_R1 2 APIDTSDVEEK 11 0 D6RIY6;Q06265-3;Q06265-4;Q06265;Q06265-2 D6RIY6 EXOSC9 Exosome complex component RRP45 1 APIDT(0.036)S(0.964)DVEEK;APIDT(0.034)S(0.966)DVEEK 205.31 6.548099999999999e-06 56515000.0 133757.0 204393.0 128341.0 138264.0 179934.0 162339.0 172716.0 176704.0 134251.0 150551.0 True False 131849.6006519703 203919.74056636842 117789.2983905864 148432.3957951828 169350.63588385505 155396.1394006924 181658.38937412135 184914.31292966745 119130.23865429667 176573.53975340255 0.746712111203681 1.1548714538495222 0.6670835197339731 0.8406264947878325 0.9590940755923294 0.8800647006211355 1.028797347710309 1.0472368237501122 0.6746777508151588 1.0 17.42990964003547 -6.260170261295738 24.71783464936724 0.9362855476493168 0.8607025516279957 0.05896075792763311 0.15312359241908008 341.4995170021282 6651179.557922101 0.04524076330184012 0.0552004896975336 5.493254734628028e-07 6.260170261295738 -0.07558299602132112 APIIAVT(ph)RNPQTAR ddPTM_PC-9_AZD4547_30min_R2 2 APIIAVTRNPQTAR 14 1 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 1 APIIAVT(0.978)RNPQT(0.022)AR;APIIAVT(0.993)RNPQT(0.007)AR 75.998 0.012125 21058100.0 24950.0 16928.6 27563.3 48303.0 37016.0 32388.0 25093.0 31578.0 27865.0 26470.0 True False 32883.58100776096 22400.438893184073 27197.79263245973 37167.48962391073 31876.967342669483 30362.77324000852 27326.22838841782 26698.345690251175 29337.88701247502 25543.293356840953 1.2873665329045811 0.8769597005463993 1.0647723554087307 1.4550782119078867 1.2479583935143688 1.1886788761276479 1.069800515018529 1.0452193974079258 1.1485553801784063 1.0 14.640656926644526 -7.263762543701758 22.144441980334538 1.0696620815331452 1.1821459526674396 0.14336383960206123 0.1444046325866288 105.13631342056236 1002124.6770043367 0.06323399284415036 0.045026431680229476 5.4480044833189044e-08 7.263762543701758 0.11248387113429437 APIIAVTR ddPTM_PC-9_Lapatinib_30min_R1 1 APIIAVTR 8 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 116.9 0.016447999999999997 41027000.0 70039.0 62977.0 65055.0 49548.0 52695.0 64781.0 45027.0 43909.0 67825.0 53553.0 False True 69040.23101642037 62831.18062579538 59706.4290195621 53191.92520728262 49595.58370235605 62010.467641886724 47358.27774119696 45949.17243768537 60185.834271086846 62809.56469511297 1.0991993234080188 1.0003441503023838 0.9505945361886529 0.8468761957750255 0.7896183319069388 0.9872774623243262 0.7539978659473462 0.7315633002828396 0.9582272152854091 1.0 15.938696650250693 -5.1911630214005635 1.3492283940187957 0.8520716135617561 1.1141006321791396 0.4004385254549746 0.09050708450681459 0.6462971830820115 1.7004190306555897 0.027387964295136798 0.1890822179801362 6.439275086583998e-06 5.1911630214005635 0.2620290186173835 APILIATDVASR ddPTM_PC-9_Lapatinib_30min_R1 1 APILIATDVASR 12 0 P17844-2;P17844;J3KTA4;A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2;A0A0U1RQJ0 P17844-2;A0A1X7SBZ2 DDX5;DDX17 Probable ATP-dependent RNA helicase DDX5;Probable ATP-dependent RNA helicase DDX17 0 123.75 0.0015788 7609600.0 17127.0 11695.0 19238.0 15189.0 16485.0 17370.0 21084.0 17028.0 14109.0 10504.0 False True 16882.765839292864 11667.920946038657 17656.325900827527 16306.04972901864 15515.384710756989 16627.12559144768 22175.626355195684 17819.18304377022 12519.895845643407 12319.602404299781 1.370398596094339 0.947102070596558 1.4331895885426567 1.3235857127440662 1.2594062861429536 1.3496479063029247 1.8000277628648111 1.446408939102692 1.0162581092124954 1.0 13.58866807563088 -5.290791625670306 24.93050953452416 1.3594517716994872 1.1587501267009015 0.06487349531497721 0.23560031862271572 1379.4827038786173 1171669.7832759607 0.061813661126601645 0.12870325438939434 5.119273991992456e-06 5.290791625670306 -0.20070164499858567 APIQDIWYHEDR ddPTM_PC-9_AZD4547_30min_R2 1 APIQDIWYHEDR 12 0 J3QLR8;Q9Y3D9 J3QLR8 MRPS23 28S ribosomal protein S23, mitochondrial 0 119.25 0.00045932 2561000.0 10016.0 7271.6 8723.1 12856.0 9938.5 10664.0 8867.7 10489.0 9487.3 11716.0 False True 13200.879654257862 9622.002496111747 8607.425994427711 9892.247823220021 8558.710825997425 9997.178394203125 9656.908120988825 8868.166063241637 9988.77930929317 11305.826406072856 1.167617401870516 0.8510658266381436 0.7613265660796176 0.8749690175595178 0.7570177109211729 0.8842501233552641 0.8541532280914622 0.7843890171954307 0.8835072245517371 1.0 13.464778830141132 -4.762382940181717 6.325311211560839 0.8389643551303195 1.177627955159882 0.655332067110916 0.06871662666748345 0.0667584997190964 11.751864705876647 0.01562540283150958 0.09780989693690728 1.7282917618259448e-05 4.762382940181717 0.33866360002956253 APIQDIWYHEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APIQDIWYHEDR 12 0 J3QLR8;Q9Y3D9 J3QLR8 MRPS23 28S ribosomal protein S23, mitochondrial 0 78.486 0.02105 0.0 6023.6 11205.0 8928.4 8657.4 10294.0 8750.0 7395.5 8663.1 7859.0 5367.6 False True 7043.276508476987 12317.358348734788 9141.286917145557 8172.353945669499 8276.9645960973 8291.134596505346 6694.944701216684 8435.702804313187 7973.923007232726 6340.703390101783 1.1108036561798431 1.9425854815986063 1.4416834150317852 1.2888718242879855 1.3053700964814308 1.3076048643827596 1.0558678255898064 1.3304048912746531 1.257577041007863 1.0 12.630427175677191 -5.717308009215084 3.325677085789674 1.2307624379222626 1.5586041715191177 0.26167110062981713 0.21415329523404775 0.28327539971896415 6.393039246993797 0.05752791674151572 0.10244114497625117 1.917308469783391e-06 5.717308009215084 0.3278417335968551 APKPDGPGGGPGGSHMGGNYGDDR ddPTM_PC-9_Lapatinib_30min_R1 2 APKPDGPGGGPGGSHMGGNYGDDR 24 1 H3BPE7;P35637-2;P35637 H3BPE7 FUS RNA-binding protein FUS 0 ; 57.986000000000004 0.0040578 25483000.0 80456.0 52754.0 48318.0 44968.0 50544.0 45400.0 41962.0 42234.0 50973.0 39887.0 False True 79308.68268617647 52631.85135419613 44345.48055287371 48275.0967288505 47571.10129332735 43458.347832569045 44134.5870383571 44196.34582279724 45231.88397051395 46781.414803913314 1.6953032100162608 1.125058991370937 0.9479294446042313 1.03192896006241 1.0168803464521978 0.9289660865266031 0.9434213826868955 0.9447415390930025 0.9668772131006661 1.0 15.513647873127871 -4.740934520044072 2.5670979578326953 0.9719964175319507 1.8958987731040373 0.977092746367233 0.0331375514516795 0.08329084149004633 0.6433624075779306 0.00944560486198815 0.1768852638354035 1.8157894144622268e-05 4.740934520044072 0.9239023555720867 APKPPTDGSTS(ph)PTSTPSEDQEALGK ddPTM_PC-9_AZD4547_30min_R2 1 APKPPTDGSTSPTSTPSEDQEALGK 25 1 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;S4R3G4;F8WBN2;F6SRV7;Q8NHM5-5 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 APKPPT(0.001)DGS(0.261)T(0.261)S(0.348)PT(0.094)S(0.026)T(0.007)PS(0.002)EDQEALGK 69.071 0.00027072 19393000.0 27781.0 30472.0 30426.0 44579.0 49776.0 46783.0 46316.0 50828.0 34519.0 39192.0 True False 36614.7801193029 40321.478087562136 30022.53136000476 34302.00028868427 42865.46159630202 43857.65161440406 50438.03427401905 42973.70051124472 36343.603868064776 37819.90000911638 0.9681352967743704 1.066144492128291 0.7938289459455977 0.9069828392041192 1.133410230750727 1.1596448325837003 1.333637430608254 1.1362721874168369 0.9609650966635092 1.0 15.206857928544617 -6.267540186580986 22.84396443901835 1.1400672240431173 0.9332320016183371 0.3880523426548317 0.11340812569082843 151.3797376027825 566828.082683717 0.03648436004975198 0.04252786770545909 5.400821370199373e-07 6.267540186580986 -0.20683522242478025 APKPPTDGSTS(ph)PTSTPSEDQEALGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APKPPTDGSTSPTSTPSEDQEALGK 25 1 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;S4R3G4;F8WBN2;F6SRV7;Q8NHM5-5 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 APKPPTDGS(0.017)T(0.242)S(0.533)PT(0.091)S(0.09)T(0.028)PSEDQEALGK 90.899 2.5967e-06 11304000.0 67140.0 62104.0 65320.0 72133.0 93739.0 78841.0 84747.0 67721.0 62128.0 70487.0 True False 78505.47592455403 68269.2746889625 66877.47652747948 68091.62186834142 75371.51586104199 74706.43916835178 76719.15064485291 65943.39550633071 63036.50446537151 83265.7351252151 0.9428305149350741 0.8198963785799656 0.8031812416825368 0.8177628140308275 0.9051924629945106 0.8972050634754879 0.9213772091182835 0.7919631695698712 0.7570521580164655 1.0 16.34543531049639 -4.748227139754346 24.76052935609688 0.8524241725273685 0.9428307616362788 0.11643114759099837 0.06982739980418898 1294.2294116801343 2425301.1535157277 0.017453890459560223 0.3239022988717688 1.7855534707580236e-05 4.748227139754346 0.0904065891089103 APKPPTDGSTS(ph)PTSTPSEDQEALGK ddPTM_PC-9_Lapatinib_30min_R1 2 APKPPTDGSTSPTSTPSEDQEALGK 25 1 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;S4R3G4;F8WBN2;F6SRV7;Q8NHM5-5 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 APKPPTDGS(0.002)T(0.021)S(0.959)PT(0.012)S(0.004)T(0.001)PSEDQEALGK;APKPPTDGS(0.014)T(0.147)S(0.614)PT(0.147)S(0.056)T(0.021)PS(0.002)EDQEALGK 107.15 2.4796999999999996e-07 26142000.0 60563.0 73466.0 74175.0 72855.0 77743.0 87967.0 78015.0 75398.0 76691.0 57264.0 True False 59699.36051410602 73295.89399073772 68076.61782378012 78212.99973715533 73170.30958861872 84204.85647109256 82054.23496967339 78901.26633393143 68053.25198796784 67162.00610051616 0.8888859041041541 1.0913297301012934 1.0136179929154459 1.1645423399071793 1.0894598573948253 1.253757315483842 1.2217359148991052 1.1747901963477094 1.0132700903263347 1.0 16.035357703154375 -3.807926756153779 0.810648639905992 1.1434002172225504 1.397830944282986e-16 0.3818740833710511 0.08510495676384133 10.162828520607016 1.5821248629536788 0.03050147348323332 15.129240958825857 0.00015562280676314062 3.807926756153779 -1.1434002172225501 APKPPTDGSTSPT(ph)STPSEDQEALGK ddPTM_PC-9_AZD4547_30min_R2 1 APKPPTDGSTSPTSTPSEDQEALGK 25 1 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;S4R3G4;F8WBN2;F6SRV7;Q8NHM5-5 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 APKPPTDGS(0.004)T(0.019)S(0.082)PT(0.648)S(0.176)T(0.071)PS(0.001)EDQEALGK 99.07799999999999 1.3168e-06 19086000.0 64119.0 59181.0 66159.0 84579.0 78882.0 76465.0 65080.0 87800.0 66195.0 88006.0 True False 84507.50824194895 78310.10090246839 65281.68843247734 65080.61828252378 67930.59590243275 71683.63146218525 70871.99392333432 74232.52744328482 69693.93256022903 84924.93672694167 0.9950847359906211 0.9221096172759964 0.7686986996808362 0.7663310776642303 0.7998898618064249 0.844082247510751 0.8345251307187705 0.8740957639092974 0.8206533351248204 1.0 16.3739006177789 -10.017650518403387 11.751224626865373 1.000000475051785 0.843710111988575 0.32114010003430904 0.06643388114844763 0.0 0.0 0.06940136278967052 0.016832302902566043 9.60172982585569e-11 10.017650518403387 -0.15629036306320998 APKPPTDGSTSPT(ph)STPSEDQEALGK ddPTM_PC-9_Lapatinib_30min_R1 2 APKPPTDGSTSPTSTPSEDQEALGK 25 1 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;S4R3G4;F8WBN2;F6SRV7;Q8NHM5-5 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 APKPPTDGS(0.001)T(0.01)S(0.05)PT(0.667)S(0.206)T(0.065)PS(0.001)EDQEALGK;APKPPTDGS(0.004)T(0.054)S(0.054)PT(0.589)S(0.219)T(0.079)PSEDQEALGK 94.301 2.0759e-06 30844000.0 71483.0 117606.0 104124.0 90595.0 96262.0 116652.0 88432.0 112378.0 98437.0 80666.0 True False 70463.63931162332 117333.69053269131 95563.32665026314 97257.65851606062 90600.05841837371 111663.06588909343 93010.57625890074 117599.49213605902 87349.98847243606 94609.01061931145 0.7447878257088589 1.2401957251706144 1.0100869465255449 1.0279957255594483 0.9576261058572001 1.1802582561443775 0.9831048401209637 1.24300519967656 0.9232734588454339 1.0 16.52968997280474 -6.725107934226536 24.99969926965773 1.0759401800159534 1.0122420175474138 0.0485906684077988 0.14255379434724558 624.8886349947339 429984.85945089575 0.044143172046016595 0.044141901047797555 1.8831810086046204e-07 6.725107934226536 -0.06369816246853954 APLATGEDDDDEVPDLVENFDEASKNEAN ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APLATGEDDDDEVPDLVENFDEASKNEAN 29 1 P20290;P20290-2 P20290 BTF3 Transcription factor BTF3 0 46.63 0.030463999999999998 1460000.0 4488.1 3583.9 4921.7 5306.0 5536.7 4419.9 4865.3 4173.8 4556.9 3064.5 False True 5247.846685984385 3939.6859068300414 5039.051993651192 5008.722022284101 4451.823380533511 4188.112663210737 4404.423562278352 4064.2421725066515 4623.536041692174 3620.069591431349 1.4496535366076828 1.0882901025315146 1.3919765535940394 1.3835982695304176 1.2297618231071885 1.156914959072593 1.216668202374771 1.1226972492812437 1.2771953480220422 1.0 11.821801716293182 -6.505826565910229 4.62247728601813 1.167760026978102 1.3157721870913535 0.3437538760401688 0.11174859507631256 0.2602088895399301 14.27656823969063 0.035114334670179354 0.03776035346989124 3.120135351242068e-07 6.505826565910229 0.14801216011325136 APLKPYPVS(ph)PSDK ddPTM_PC-9_Lapatinib_30min_R1 1 APLKPYPVSPSDK 13 1 J3KR24;A0A0A0MSX9;P41252;Q5TCC6 J3KR24 IARS Isoleucine--tRNA ligase, cytoplasmic 1 APLKPYPVS(0.665)PS(0.335)DK 133.25 0.00022311 7508900.0 17326.0 31483.0 36034.0 33358.0 42196.0 33235.0 36965.0 33049.0 33701.0 32649.0 True False 17078.928062800725 31410.103047809753 33071.423615262465 35811.258599025874 39714.11424052786 31813.61652456899 38878.866828865896 34584.57719130619 29905.238492737164 38292.33614794209 0.4460142624053137 0.8202712659383617 0.8636564634628537 0.9352069422108226 1.0371295730585028 0.8308089744552898 1.0153171819723337 0.9031722968713372 0.7809718993690682 1.0 15.224768058704335 -4.540043414164603 1.6131674631493187 0.9251709098099982 3.008715484180387e-14 0.7731099953470133 0.07718684553012271 0.9090554906094895 1.4087725491685748 0.021048334292676506 1.5904467539818332 2.8837432158799694e-05 4.540043414164603 -0.9251709098099681 down APLKPYPVSPS(ph)DK ddPTM_PC-9_AZD4547_30min_R2 2 APLKPYPVSPSDK 13 1 J3KR24;A0A0A0MSX9;P41252;Q5TCC6 J3KR24 IARS Isoleucine--tRNA ligase, cytoplasmic 1 APLKPYPVS(0.296)PS(0.704)DK;APLKPYPVS(0.009)PS(0.991)DK 181.71 0.00038206 20995200.0 55266.0 64081.0 64039.0 55349.0 63488.0 72548.0 82327.0 89777.0 73422.0 62014.0 True False 72839.43839578825 84793.93007774578 63189.80101766076 42589.14318352557 54673.78708265072 68011.56209139602 89653.94351146818 75904.02752022551 77302.93702601612 59842.908735592544 1.2171774389780925 1.4169419881041514 1.0559279679544988 0.7116823711176824 0.9136218181542468 1.13650160943706 1.4981548424992424 1.26838800325694 1.291764365391533 1.0 15.86889268038374 -7.012481026697441 24.08548997293645 1.291283317877756 1.0590365118240825 0.17142658516590947 0.2056893540876519 643.3761823941346 1241566.5366217247 0.08355848302538108 0.0682078727844431 9.716704006400459e-08 7.012481026697441 -0.23224680605367354 APLKPYPVSPS(ph)DK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APLKPYPVSPSDK 13 1 J3KR24;A0A0A0MSX9;P41252;Q5TCC6 J3KR24 IARS Isoleucine--tRNA ligase, cytoplasmic 1 APLKPYPVS(0.011)PS(0.989)DK;APLKPYPVS(0.006)PS(0.994)DK 147.56 0.00026464 13818500.0 85660.0 116982.0 99369.0 99511.0 111883.0 79205.0 115387.0 81458.0 70697.0 74805.0 True False 100160.54613788071 128595.1998528953 101738.33381903122 93935.72128901503 89960.32930883559 75051.3503675664 104456.70803046321 79319.81381188527 71730.80987941618 88366.55434394562 1.1334666931566642 1.455247415808127 1.1513217254464756 1.0630234706605484 1.0180359523659435 0.8493185111127793 1.1820842037575723 0.8976225722590915 0.8117416188960045 1.0 16.431212810112427 -5.7632851233218565 1.8515082246512897 0.9613477287000813 1.2965356011234614 0.5343243695439708 0.12254280836296756 0.257176303512334 1.7972182174954214 0.037549989993328314 0.07654596386126031 1.7247052155244855e-06 5.7632851233218565 0.3351878724233801 APLKPYPVSPS(ph)DK ddPTM_PC-9_Lapatinib_30min_R1 1 APLKPYPVSPSDK 13 1 J3KR24;A0A0A0MSX9;P41252;Q5TCC6 J3KR24 IARS Isoleucine--tRNA ligase, cytoplasmic 1 APLKPYPVS(0.329)PS(0.671)DK 125.73 0.000666 10819000.0 10823.0 32407.0 33264.0 29036.0 36303.0 28663.0 34072.0 37673.0 31171.0 23587.0 True False 10668.662035304878 32331.963582580152 30529.162322753255 31171.404301256527 34167.728914444095 27437.150306716438 35836.08144442361 39423.42511204811 27660.19373481825 27663.981522298076 0.38565171924748387 1.16873861980133 1.1035708037234535 1.126786622385912 1.2350980240101659 0.9918004855736762 1.2954057757571358 1.425081385348365 0.9998630787301253 1.0 14.755721190018155 -4.761183880528202 24.994295100049587 1.1630243472322481 0.385650854165122 0.7454632369136236 0.13371239877062052 2.932648959946364 286342.42749439704 0.03282694044348941 0.18560465970430923 1.7330700595510196e-05 4.761183880528202 -0.7773734930671261 APLNVQFNSPLPGDAVK ddPTM_PC-9_Lapatinib_30min_R1 2 APLNVQFNSPLPGDAVK 17 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 190.57 4.8280000000000006e-08 7521400.0 79571.0 65676.0 70872.0 59667.0 59948.0 57383.0 62551.0 53405.0 65214.0 55932.0 False True 78436.30294846566 65523.93125712147 65045.17773383144 64055.11022327712 56421.97650230271 54928.862856306354 65789.58471560641 55886.39126453769 57868.912586135746 65599.7716752948 1.1956795114578906 0.9988438920405283 0.9915457946376934 0.9764532495682541 0.8600940988267418 0.8373331408559282 1.0028935015391691 0.8519296612976593 0.8821511280950001 1.0 16.001403172998096 -1.5228787452805954 0.6871476724873478 0.904033540369888 33.854685407935186 0.668545033577487 0.05886068528967539 153.63012307980122 0.858658357724035 0.02335857667107315 7759.5464823276525 0.029999999999982187 1.5228787452805954 32.9506518675653 APLS(ph)PGRK ddPTM_PC-9_Lapatinib_30min_R1 1 APLSPGRK 8 1 A0A1B0GW05 A0A1B0GW05 1 APLS(1)PGRK 56.013000000000005 0.039967 16406000.0 104780.0 119590.0 47099.0 35721.0 41967.0 46451.0 43288.0 35300.0 75938.0 16244.0 True False 103285.81798570107 119313.09670258794 43226.70202739762 38348.04150176281 39498.58357029658 44464.39901256973 45529.24083018931 36940.166868985674 67385.06277740943 19051.753756230544 5.421328624506457 6.26257814525703 2.2689093392917217 2.0128352482627356 2.0732255977945995 2.333874328919899 2.389766391731772 1.9389378711083245 3.536948022717978 1.0 14.217636186662318 -5.265909820517119 24.90161053029242 2.229004525000315 5.841953552444559 0.849541834920117 0.6138883161446849 103.56932043086277 576913.5487227532 0.14884921772411863 0.32778381454935096 5.42113446367675e-06 5.265909820517119 3.6129490274442437 APLS(ph)PSLNSRPSPISATPPALVPETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APLSPSLNSRPSPISATPPALVPETR 26 1 X6RKU3;Q6P3S6 X6RKU3 FBXO42 F-box only protein 42 1 APLS(0.786)PS(0.15)LNS(0.037)RPS(0.008)PIS(0.01)AT(0.009)PPALVPETR 58.861000000000004 0.0014798 17438000.0 12190.0 3698.2 4767.9 4531.5 18130.0 14574.0 14457.0 10970.0 14429.0 13217.0 True False 14253.52623652541 4065.332855447657 4881.584818361443 4277.614746321224 14577.556647293968 13809.713783939289 13087.528300383961 10682.049123675772 14639.996828013866 15613.137474285566 0.912918768569136 0.2603789829009804 0.31265879945022496 0.2739753462983558 0.9336724711034426 0.8844931908582455 0.838238203047836 0.6841705673359266 0.9376716788746376 1.0 13.930472856888862 -6.267169695014369 24.97040218144644 0.8620820267918696 0.41805953014833946 0.5582614398887797 0.19084078980231142 347.10492943453687 1512541.0364936392 0.0585263620065679 0.0681627243607614 5.405430713845099e-07 6.267169695014369 -0.44402249664353016 APLSPS(ph)LNSRPSPISATPPALVPETR ddPTM_PC-9_AZD4547_30min_R2 1 APLSPSLNSRPSPISATPPALVPETR 26 1 X6RKU3;Q6P3S6 X6RKU3 FBXO42 F-box only protein 42 1 APLS(0.017)PS(0.418)LNS(0.418)RPS(0.035)PIS(0.056)AT(0.056)PPALVPETR 61.611999999999995 0.00083718 37784000.0 2917.5 2730.4 6244.5 14196.0 14365.0 5222.3 4658.2 5516.0 5184.0 6692.5 True False 3845.204312230164 3612.9484041178684 6161.69384991618 10923.331526013646 12370.667707949184 4895.748755443265 5072.770775870872 4663.628945070161 5458.015656654244 6458.1976120384625 0.595398986407984 0.5594360255225265 0.9540887752382209 1.6913901032777179 1.9154984797754604 0.7580673509149518 0.785477788170329 0.7221254636706812 0.8451298620036308 1.0 12.656915870789906 APLSPS(ph)LNSRPSPISATPPALVPETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APLSPSLNSRPSPISATPPALVPETR 26 1 X6RKU3;Q6P3S6 X6RKU3 FBXO42 F-box only protein 42 1 APLS(0.187)PS(0.652)LNS(0.159)RPS(0.003)PISATPPALVPETR 70.391 0.00012144 9087800.0 1998.0 939.98 1800.3 1405.0 0.0 1589.5 1862.8 4333.1 3398.6 710.4 True False 2336.2219377012098 1033.295002288597 1843.2259796757712 1326.2824050714587 0.0 1506.1438218451708 1686.3420984959012 4219.360716298949 3448.2980954804875 839.1898964766942 2.783901411956633 1.231300575265319 2.1964349039645055 1.5804318076752393 0.0 1.7947592412261593 2.0094880855643544 5.027897421088801 4.109079613515405 1.0 9.712853498301541 -7.598670175977874 7.474730199960559 3.6694440807503814 1.5646070991138026 0.30891003779440596 1.1691238901291143 0.23396576739354144 19.604359658577536 0.5383673592406701 0.30900184023231053 2.519589698388615e-08 7.598670175977874 -2.104836981636579 APLSPSLNSRPS(ph)PISATPPALVPETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APLSPSLNSRPSPISATPPALVPETR 26 1 X6RKU3;Q6P3S6 X6RKU3 FBXO42 F-box only protein 42 1 APLS(0.044)PS(0.136)LNS(0.101)RPS(0.47)PIS(0.183)AT(0.067)PPALVPETR 53.603 0.0036735 16810000.0 8896.1 9869.6 3040.0 8772.2 8517.0 10408.0 12437.0 10094.0 4339.8 8078.4 True False 10402.034024015884 10849.388662085934 3112.4851292641997 8280.722073856126 6848.154989796066 9862.186157763157 11258.877323917503 9829.043195477047 4403.261364905022 9542.949971420781 1.0900229022648014 1.1369009262940364 0.3261554486385727 0.8677318961804501 0.7176140512425314 1.0334525683670588 1.1798109973997117 1.029979537240901 0.4614151156709304 1.0 13.22021959400254 -6.004519632908971 24.999521313579002 0.9134275673886266 0.832502282517271 0.005543031873877613 0.2764897810282845 1281.2632670408107 7087170.265592325 0.08253691741137695 0.11897002588520832 9.896471244310117e-07 6.004519632908971 -0.08092528487135564 APLSPSLNSRPSPISAT(ph)PPALVPETR ddPTM_PC-9_AZD4547_30min_R2 1 APLSPSLNSRPSPISATPPALVPETR 26 1 X6RKU3;Q6P3S6 X6RKU3 FBXO42 F-box only protein 42 1 APLS(0.016)PS(0.15)LNS(0.15)RPS(0.038)PIS(0.013)AT(0.633)PPALVPET(0.001)R 51.827 0.010894 45610000.0 20127.0 20277.0 16527.0 25779.0 18406.0 21088.0 7463.3 14026.0 7146.6 7845.0 True False 26526.967332392986 26831.14371165325 16307.841181450034 19836.04983157971 15850.644610686586 19769.364026346164 8127.519241672124 11858.60398541589 7524.354685926931 7570.348937832158 3.504061378178591 3.5442413463356957 2.1541729866575925 2.6202292647899994 2.0937799222799853 2.61142044953179 1.0735990254102497 1.5664540806241507 0.9939244211484922 1.0 12.886144084117225 -4.8803986820296785 0.26141339900971866 0.765965117668965 5.799147956317386 0.8157077518450642 0.39254676008434514 3.6472495564148297 0.22009771427299127 0.5434392643475862 5.930420613888484 1.3170471350878388e-05 4.8803986820296785 5.033182838648421 up APNPT(ph)ATSPPASAPR ddPTM_PC-9_Lapatinib_30min_R1 1 APNPTATSPPASAPR 15 0 Q8IV32 Q8IV32 CCDC71 Coiled-coil domain-containing protein 71 1 APNPT(0.362)AT(0.294)S(0.294)PPAS(0.051)APR 87.447 0.015653999999999998 0.0 7793.0 11465.0 8187.1 6969.3 10193.0 8783.6 7434.3 10023.0 9679.0 6000.7 True False 7681.870390938825 11438.453496907507 7513.98824111992 7481.8455709032605 9593.467780209043 8407.94590357166 7819.211677690725 10488.705170760439 8588.849095611486 7037.912999569849 1.0914983449508873 1.6252621334771566 1.0676443771866984 1.0630773030812608 1.3631125847670165 1.1946646547187423 1.1110128355051603 1.4903146957630053 1.2203687508124113 1.0 12.780931964725095 -11.89043372840488 1.62477652415674 6.523832154179245e-05 1.2528225708066434 0.14319826698491223 0.18114715982025648 1637835.4837124483 172099.24540045662 5981591.371104686 0.0470925956547516 1.2869636235309994e-12 11.89043372840488 1.2527573324851016 APNPTAT(ph)SPPASAPR ddPTM_PC-9_AZD4547_30min_R2 1 APNPTATSPPASAPR 15 0 Q8IV32 Q8IV32 CCDC71 Coiled-coil domain-containing protein 71 1 APNPT(0.074)AT(0.461)S(0.461)PPAS(0.003)APR 108.06 0.0026747 0.0 7378.7 8244.5 10648.0 15460.0 13903.0 9374.0 9772.7 11116.0 8232.5 12665.0 True False 9724.973113505645 10909.373395015306 10506.80056272039 11895.935854618972 11972.808433248694 8787.842298130172 10642.451367771526 9398.277620268294 8667.653143018144 12221.602204925974 0.7957199842084492 0.8926303779236271 0.8596909297608766 0.9733532195823114 0.9796431132755243 0.7190417549826806 0.8707901950434973 0.7689889969156642 0.7092075979632692 1.0 13.577145808861628 -6.759449440720532 24.999955232137673 0.8027415581050265 0.9015992909119585 0.176431931401261 0.0920443822620602 84.23905090450637 1058314.0802155565 0.03052072090581829 0.029075836081804536 1.7400052525143392e-07 6.759449440720532 0.098857732806932 APPAPLAASEVTNSNS(ph)AER ddPTM_PC-9_Lapatinib_30min_R1 1 APPAPLAASEVTNSNSAER 19 0 Q9Y2U8 Q9Y2U8 LEMD3 Inner nuclear membrane protein Man1 1 APPAPLAAS(0.001)EVT(0.039)NS(0.123)NS(0.837)AER 115.74 0.00066123 0.0 19336.0 15685.0 19408.0 17764.0 16722.0 12853.0 9784.4 11315.0 15905.0 12993.0 True False 19060.265094211867 15648.682346183532 17812.3491570465 19070.42381896684 15738.44483671692 12303.307151806397 10290.988356563117 11840.736207438329 14113.611412924964 15238.822737915752 1.2507701823178226 1.02689575273082 1.168879608575507 1.251436816803287 1.0327861349524106 0.8073659864284993 0.6753138699460086 0.7770112174070615 0.9261615320065935 1.0 13.895463832526717 -6.615102061718251 3.532906109239941 0.8130089879878603 1.1625529800365737 0.7075759133935178 0.10166258146064862 0.12608959058933747 3.092729557629447 0.03521468562220441 0.035379638000700764 2.4260398946603714e-07 6.615102061718251 0.34954399204871345 APPGQPAEPDAPRS(ph)SPGPGAR ddPTM_PC-9_Lapatinib_30min_R1 2 APPGQPAEPDAPRSSPGPGAR 21 1 Q8IX07 Q8IX07 ZFPM1 Zinc finger protein ZFPM1 1 APPGQPAEPDAPRS(0.5)S(0.5)PGPGAR;APPGQPAEPDAPRS(0.809)S(0.191)PGPGAR 96.561 0.00014861 4419900.0 23966.1 17203.0 23435.9 17865.8 13699.699999999999 14778.7 15244.2 18165.8 20459.6 10935.099999999999 True False 23624.33901915552 17163.167510449177 21509.090767190148 19179.710530561675 12893.9105806465 14146.649451832347 16033.470085556539 19009.84938551332 18155.224398860708 12825.217464895146 1.8420224907545972 1.3382359837116022 1.6770936497618287 1.495468640828889 1.0053560975429368 1.1030338854334587 1.2501519081015928 1.4822243316767603 1.4155880357237387 1.0 13.64669566798341 -6.062235656030302 7.201265316034704 1.2308561909455742 1.590597475886535 0.4985331913787675 0.18778622461250763 0.2536193725837964 25.57870655599687 0.05738919541738279 0.07482104411424872 8.664915741935774e-07 6.062235656030302 0.3597412849409609 APPGQPAEPDAPRSS(ph)PGPGAR ddPTM_PC-9_AZD4547_30min_R2 1 APPGQPAEPDAPRSSPGPGAR 21 1 Q8IX07 Q8IX07 ZFPM1 Zinc finger protein ZFPM1 1 APPGQPAEPDAPRS(0.308)S(0.692)PGPGAR 50.47 0.019903 4178000.0 4171.3 5028.8 5565.1 11406.0 7351.0 6650.6 6723.9 10715.0 6950.6 7754.6 True False 5497.686631570073 6654.261256456173 5491.303137828256 8776.522920943336 6330.440537496309 6234.73693065335 7322.314074079723 9059.242956204995 7317.994526068869 7483.113814316541 0.7346790076948998 0.8892369435468663 0.7338259545541599 1.1728437036668173 0.8459634177132305 0.8331741418559181 0.9785116538079136 1.2106247721200012 0.9779344144236095 1.0 12.869423002595328 -3.0481317106106136 0.2832794119662684 1.0550429889103 1.7377169735791278e-11 0.3063357710125131 0.1294075750045436 28.668553828014282 0.8644695510346153 0.15088618842326768 12.617955313139172 0.0008950932650717957 3.0481317106106136 -1.0550429888929227 APPGQPAEPDAPRSS(ph)PGPGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APPGQPAEPDAPRSSPGPGAR 21 1 Q8IX07 Q8IX07 ZFPM1 Zinc finger protein ZFPM1 1 APPGQPAEPDAPRS(0.255)S(0.745)PGPGAR 44.641000000000005 0.037096 5783200.0 7892.0 7641.7 15490.0 11962.0 11431.0 8101.5 9400.1 12126.0 10750.0 5192.9 True False 9227.959725894874 8400.317473764091 15859.340346152128 11291.80792132725 9191.177608120097 7676.643078124347 8509.654477169488 11807.705348559019 10907.198412998066 6134.331663026215 1.504313792081874 1.369394081574652 2.5853411940117255 1.8407560173811546 1.498317683655511 1.2514228932866782 1.3872178657147254 1.9248560392859473 1.7780581507745343 1.0 12.582690455125478 -6.259154074016405 13.118162343396262 1.5041450158124663 1.8467445225330519 0.16395797365854492 0.383985115993468 0.664309996763071 3698.628998827808 0.12209090850106971 0.1489314075941664 5.506123218251944e-07 6.259154074016405 0.3425995067205856 APPPPAAGS(ph)RR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APPPPAAGSRR 11 1 C9JI98 C9JI98 TMEM238 Transmembrane protein 238 1 APPPPAAGS(1)RR 73.219 0.011592 1492100.0 2553.4 1209.8 2780.3 831.87 3137.4 3272.4 2134.3 2681.6 2285.0 2025.2 True False 2985.640188051189 1329.9009487103388 2846.592896346468 785.2630208589287 2522.6489920143476 3100.789583269036 1932.123653006121 2611.210841390061 2318.4138022047055 2392.352728525621 1.2479933048548422 0.5558966839852003 1.1898717368909015 0.3282388134056123 1.054463650754806 1.2961255864556462 0.8076249083039131 1.0914823764300507 0.9690936351319385 1.0 11.224214400861246 APPPPIS(ph)PTQLSDVSSPR ddPTM_PC-9_Lapatinib_30min_R1 2 APPPPISPTQLSDVSSPR 18 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2 Q9P0K7-3 RAI14 Ankycorbin 1 APPPPIS(0.796)PT(0.149)QLS(0.035)DVS(0.015)S(0.005)PR;APPPPIS(0.493)PT(0.091)QLS(0.302)DVS(0.088)S(0.027)PR 110.32 0.0023439 0.0 7299.599999999999 10678.9 23274.7 15018.3 17642.0 16092.5 16505.9 17129.9 22476.0 15726.4 True False 7195.506365417308 10654.173663159656 21361.144008940155 16122.795881580132 16604.332245506514 15404.261288449728 17360.494738011024 17925.81768977444 19944.516197227396 18444.6872858892 0.39011267872901867 0.5776283163830299 1.1581190658234766 0.8741159788550391 0.9002230283518757 0.8351597969478454 0.9412192502332302 0.9718688862504213 1.0813149547124943 1.0 14.170917709112336 -5.0831744576664155 4.756689992677231 0.9562924852249336 0.42724673511835287 0.818954742825826 0.09301157074027751 0.07935636334512913 3.086314372377938 0.024415718724600473 0.07313574654172289 8.257061937790994e-06 5.0831744576664155 -0.5290457501065807 down APPPPISPT(ph)QLSDVSSPR ddPTM_PC-9_Lapatinib_30min_R1 1 APPPPISPTQLSDVSSPR 18 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2 Q9P0K7-3 RAI14 Ankycorbin 1 APPPPIS(0.363)PT(0.483)QLS(0.124)DVS(0.015)S(0.015)PR 86.411 0.008198299999999999 0.0 5450.6 6601.0 10397.0 9519.1 11346.0 8401.5 7760.9 7257.9 11676.0 8707.0 True False 5372.8734444823785 6585.715790064235 9542.198793580614 10219.166368786717 10678.650587094256 8042.187429853059 8162.721427624652 7595.128530266611 10360.925926269223 10211.993348651777 0.5261336607893232 0.6449001252956853 0.9344109879233723 1.0007024113598633 1.0456969782989616 0.7875237630187859 0.7993269432262531 0.7437459339189001 1.014584084863031 1.0 13.317976882741018 -5.132207978015667 3.511100214372566 0.905604039389145 0.5462781717349906 0.6338785588910985 0.10168887829007113 0.16771075357075496 3.6769826742592224 0.028854035438532676 0.09596202294341052 7.375509419274176e-06 5.132207978015667 -0.3593258676541544 APPQTHLPS(ph)GASSGTGSASATHGGGSPPGTR ddPTM_PC-9_Lapatinib_30min_R1 1 APPQTHLPSGASSGTGSASATHGGGSPPGTR 31 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;P46379-4;F6U341;A0A0G2JJM1;X6REW1;F6S6P2;F6TC96;F6VEM6;F6X9W3;A0A1B0GX79;A0A0G2JJR8;F6XTU0;F6U1F2;F6UR09;F6WML8 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 APPQTHLPS(0.579)GAS(0.202)S(0.202)GT(0.015)GSASAT(0.001)HGGGSPPGTR 74.3 1.4968e-06 57538000.0 11849.0 9541.1 84765.0 17878.0 39136.0 57538.0 22563.0 33279.0 88191.0 18913.0 True False 11680.03108715952 9519.00816915344 77795.94890236227 19192.80775925968 36834.09742433642 55077.233867629024 23731.201738393105 34825.26383096248 78258.00088759928 22182.086850011605 0.5265524008690556 0.4291304165166254 3.5071519387871106 0.8652390502767163 1.660533459876754 2.4829599775730844 1.0698363007437548 1.5699723865675994 3.5279818989419534 1.0 14.437107477535022 APPQTHLPSGASS(ph)GTGSASATHGGGSPPGTR ddPTM_PC-9_AZD4547_30min_R2 1 APPQTHLPSGASSGTGSASATHGGGSPPGTR 31 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;P46379-4;F6U341;A0A0G2JJM1;X6REW1;F6S6P2;F6TC96;F6VEM6;F6X9W3;A0A1B0GX79;A0A0G2JJR8;F6XTU0;F6U1F2;F6UR09;F6WML8 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 APPQTHLPS(0.027)GAS(0.094)S(0.285)GT(0.017)GS(0.078)AS(0.076)AT(0.067)HGGGS(0.256)PPGT(0.1)R 47.286 0.013973 140150000.0 5591.9 2385.7 14250.0 27512.0 17050.0 17906.0 6318.0 19167.0 11228.0 12817.0 True False 7370.007881254449 3156.8308700937605 14061.0356892154 21169.533456162815 14682.901804422798 16786.334989366205 6880.289760412216 16205.180563843322 11821.4891575837 12368.280731191173 0.5958797379710392 0.25523602986570715 1.1368625918843613 1.7115987190342505 1.187141699281975 1.357208439410118 0.5562850577171193 1.3102209527776965 0.9557908180214136 1.0 13.594357350116706 -5.27229771721384 22.453940432599218 1.1702779936700625 0.42555793504289235 0.4948312146873646 0.2930805246214362 128.94757599224437 266652.9990847901 0.07806951337421236 0.1657828552786034 5.341980308320528e-06 5.27229771721384 -0.7447200586271701 APPQTHLPSGASS(ph)GTGSASATHGGGSPPGTR ddPTM_PC-9_Lapatinib_30min_R1 1 APPQTHLPSGASSGTGSASATHGGGSPPGTR 31 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;P46379-4;F6U341;A0A0G2JJM1;X6REW1;F6S6P2;F6TC96;F6VEM6;F6X9W3;A0A1B0GX79;A0A0G2JJR8;F6XTU0;F6U1F2;F6UR09;F6WML8 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 APPQTHLPS(0.019)GAS(0.133)S(0.623)GT(0.097)GS(0.083)AS(0.011)AT(0.007)HGGGS(0.019)PPGT(0.007)R 71.359 3.2223e-05 49529000.0 6297.1 4576.9 30726.0 6260.8 13863.0 18614.0 7056.1 11709.0 28143.0 8115.1 True False 6207.302199253291 4566.3024692539 28199.826885789924 6721.240117416552 13047.605595706656 17817.9226113533 7421.43033223754 12253.042885806051 24973.238981071834 9517.784222308946 0.6521793365207689 0.4797652859738974 2.9628562937675893 0.7061769798964855 1.3708658749716225 1.872066249368154 0.7797434947981153 1.287383975052289 2.6238500892399412 1.0 13.216410032191218 APPQTHLPSGASSGTGSASAT(ph)HGGGSPPGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APPQTHLPSGASSGTGSASATHGGGSPPGTR 31 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;P46379-4;F6U341;A0A0G2JJM1;X6REW1;F6S6P2;F6TC96;F6VEM6;F6X9W3;A0A1B0GX79;A0A0G2JJR8;F6XTU0;F6U1F2;F6UR09;F6WML8 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 APPQTHLPS(0.001)GASSGTGS(0.001)AS(0.097)AT(0.677)HGGGS(0.175)PPGT(0.049)R 101.84 1.1248e-12 10516000.0 663.51 1289.3 12174.0 9873.1 11760.0 12208.0 9126.8 4649.1 8788.2 6237.1 True False 775.8291380801453 1417.293183313143 12464.274330152104 9319.942216022078 9455.71241986636 11567.790989044253 8262.243431690136 4527.066051128627 8916.71079935903 7367.836857143565 0.10529944583774706 0.19236218320157172 1.6917142129806029 1.264949590596028 1.2833770078253666 1.5700389698271586 1.121393373915356 0.6144362502732891 1.2102209878213765 1.0 12.84702540146651 -5.241714062022576 23.193289489626142 1.2186637478185312 0.14882982703638162 0.7016814491028813 0.2792488170161192 183.38675493724432 215625.91732144804 0.07587379310842067 0.19991536226753548 5.731732820785604e-06 5.241714062022576 -1.0698339207821495 APPQTHLPSGASSGTGSASATHGGGS(ph)PPGTR ddPTM_PC-9_AZD4547_30min_R2 4 APPQTHLPSGASSGTGSASATHGGGSPPGTR 31 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;P46379-4;F6U341;A0A0G2JJM1;X6REW1;F6S6P2;F6TC96;F6VEM6;F6X9W3;A0A1B0GX79;A0A0G2JJR8;F6XTU0;F6U1F2;F6UR09;F6WML8 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 APPQTHLPSGASSGTGSASAT(0.014)HGGGS(0.947)PPGT(0.039)R;APPQTHLPSGASSGTGSAS(0.003)AT(0.04)HGGGS(0.925)PPGT(0.032)R;APPQTHLPSGASSGTGSASAT(0.003)HGGGS(0.913)PPGT(0.085)R;APPQTHLPS(0.001)GAS(0.002)S(0.002)GT(0.002)GS(0.002)AS(0.006)AT(0.029)HGGGS(0.656)PPGT(0.3)R 209.83 7.1125e-47 184015700.0 4128.57 3891.4500000000003 46954.0 111026.0 64670.0 49518.0 22149.100000000002 73714.0 28127.7 48362.3 True False 5441.3693804092845 5149.2851110476395 46331.35928080143 85430.67103460054 55691.68678545588 46421.631632047094 24120.32699150781 62323.195079206285 29614.47279816234 46669.15059733847 0.11659456644834681 0.11033595094703313 0.9927619999032872 1.8305598010920865 1.193329770793642 0.9946963044725847 0.5168366401098242 1.3354259565795603 0.634562069785158 1.0 15.510181589295064 -5.278495186783634 5.510427980139971 1.0879821504930371 0.10488956886555188 0.5506476984856351 0.34286694912312843 0.11866919649706104 12.728314580164849 0.09403526490919432 0.21772291842255184 5.266290514072042e-06 5.278495186783634 -0.9830925816274853 APPQTHLPSGASSGTGSASATHGGGS(ph)PPGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 APPQTHLPSGASSGTGSASATHGGGSPPGTR 31 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;P46379-4;F6U341;A0A0G2JJM1;X6REW1;F6S6P2;F6TC96;F6VEM6;F6X9W3;A0A1B0GX79;A0A0G2JJR8;F6XTU0;F6U1F2;F6UR09;F6WML8 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 APPQTHLPSGASSGTGSAS(0.001)AT(0.069)HGGGS(0.903)PPGT(0.026)R;APPQTHLPS(0.001)GAS(0.007)S(0.007)GT(0.005)GS(0.005)AS(0.082)AT(0.152)HGGGS(0.667)PPGT(0.073)R;APPQTHLPSGASSGTGSAS(0.001)AT(0.009)HGGGS(0.759)PPGT(0.232)R;APPQTHLPS(0.009)GAS(0.041)S(0.036)GT(0.022)GS(0.022)AS(0.181)AT(0.181)HGGGS(0.35)PPGT(0.158)R 104.57 2.2500999999999996e-15 132445000.0 7242.2 13837.3 63786.9 48856.3 74027.0 68897.2 52256.1 36285.2 52519.2 25901.4 True False 8468.161420029885 15210.975696470134 65307.82160916538 46119.03990526173 59521.94075726593 65284.10954541111 47306.02390659852 35332.75194734733 53287.19394343519 30597.118784630427 0.27676336061693557 0.49713751819373675 2.134443509823901 1.5073000902434084 1.9453446311802747 2.13366853280985 1.5460940698233758 1.1547738267792622 1.7415755489435973 1.0 14.901108185708214 -5.18024438455944 6.200947172379737 1.669230279028899 0.3515274844251652 0.6636950488856033 0.35847988408617926 0.13273759773603194 8.148407793908996 0.09170445159103112 0.24975745779235298 6.603217696569417e-06 5.18024438455944 -1.3177027946037339 APPS(ph)PGSLAAPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APPSPGSLAAPGR 13 0 Q9Y4B5 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 APPS(0.977)PGS(0.023)LAAPGR 85.536 0.008043000000000002 3479100.0 12190.0 20046.0 19750.0 19950.0 27544.0 30540.0 20356.0 23182.0 23963.0 18272.0 True False 14253.52623652541 22036.034400601293 20220.914902292086 18832.26617877267 22146.95092625843 28938.42863740263 18427.732315322395 22573.49706335933 24313.413541457932 21584.568958927597 0.6603572331533638 1.0209161203326678 0.936822733906322 0.8724874800422387 1.0260548157529097 1.3406998625948192 0.8537456712889556 1.0458164398053778 1.1264257158770667 1.0 14.397712662201641 -6.34506797824391 4.9044828767888635 1.0737134658596874 0.8879908234167725 0.30695402779755543 0.14199143389692168 0.30410366842086944 12.763536993337112 0.04446724388645676 0.050870177639217216 4.517852228459751e-07 6.34506797824391 -0.18572264244291492 APPS(ph)PSTTSSNNNSSSSSNSGWDQLSK ddPTM_PC-9_Lapatinib_30min_R1 1 APPSPSTTSSNNNSSSSSNSGWDQLSK 27 0 E7EPF2;E7ETU5 E7EPF2 RBMS1 1 APPS(0.612)PS(0.131)T(0.131)T(0.021)S(0.017)S(0.061)NNNS(0.017)S(0.004)S(0.004)S(0.001)SNSGWDQLSK 67.793 0.00017052 4000500.0 15652.0 13735.0 14491.0 13384.0 15109.0 17502.0 13099.0 12740.0 15121.0 10716.0 True False 15428.799609774738 13703.197451375876 13299.605916877628 14368.304007715169 14220.318325436905 16753.480259154698 13777.202126100763 13331.946909656603 13417.913748810965 12568.24632182754 1.22760162513518 1.0903030622161853 1.0581910615309886 1.1432226612842102 1.1314480923834358 1.3330006295356076 1.0961912882128673 1.0607642918728228 1.067604294602962 1.0 13.617495740580372 -7.515869018343867 24.440957376010328 1.054206081790907 1.158485752541019 0.35277711835363046 0.07352902079794496 335.1727153086341 1168669.6725440605 0.035169559494435926 0.021335500290464146 3.04881436244426e-08 7.515869018343867 0.10427967075011213 APPSPGS(ph)LAAPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APPSPGSLAAPGR 13 0 Q9Y4B5 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 APPS(0.423)PGS(0.577)LAAPGR 71.976 0.024656 3427100.0 14706.0 20093.0 23704.0 21570.0 24011.0 22671.0 21281.0 18317.0 13941.0 12457.0 True False 17195.435343260262 22087.700249989113 24269.193257920597 20361.50283088354 19306.216914405704 21482.092849985445 19265.109618902337 17836.198158465733 14144.860751219168 14715.355490442256 1.1685368630359516 1.5009967149169625 1.6492427433155548 1.3836908557260816 1.311977609167869 1.459841922537192 1.309184112569702 1.212080684700447 0.9612313314759111 1.0 13.845034774570077 -7.942767749426941 1.5628426033637093 0.9692389608204652 1.4219900118184199 0.6593003969543401 0.12029514581217837 0.2475016879419033 1.0936204588449312 0.10740697815371154 0.03697635726269158 1.1408597296650134e-08 7.942767749426941 0.45275105099795465 APPTLQAETATKPQAT(ph)SAPSPAPK ddPTM_PC-9_AZD4547_30min_R2 1 APPTLQAETATKPQATSAPSPAPK 24 1 A8CG34-2;A8CG34;Q96HA1;Q96HA1-2;Q96HA1-3 A8CG34-2;Q96HA1 POM121C;POM121 Nuclear envelope pore membrane protein POM 121C;Nuclear envelope pore membrane protein POM 121 1 APPTLQAETATKPQAT(0.381)S(0.381)APS(0.237)PAPK 71.92699999999999 0.00040188 12427000.0 32476.0 32878.0 37988.0 40164.0 37109.0 39337.0 34436.0 44823.0 34258.0 40742.0 True False 42802.692457236255 43505.17053566778 37484.254299081724 30904.81032761427 31957.055897966333 36877.251171489894 37500.73728862853 37896.635280072456 36068.80794090687 39315.63498089967 1.0886939121810106 1.1065615640394328 0.9534185144737541 0.7860692150242125 0.8128332637509662 0.9379792845621242 0.9538377621739328 0.9639074963048011 0.9174163906656938 1.0 15.262815534875438 -5.34556879946116 4.217676580767827 0.9055929434228915 1.0983587612134535 0.5772087443857028 0.06281266242747462 0.1566013957450811 5.049701066515014 0.018334510372204727 0.041545026987085454 4.512645318792185e-06 5.34556879946116 0.192765817790562 APPTLQAETATKPQATSAPS(ph)PAPK ddPTM_PC-9_AZD4547_30min_R2 1 APPTLQAETATKPQATSAPSPAPK 24 1 A8CG34-2;A8CG34;Q96HA1;Q96HA1-2;Q96HA1-3 A8CG34-2;Q96HA1 POM121C;POM121 Nuclear envelope pore membrane protein POM 121C;Nuclear envelope pore membrane protein POM 121 1 APPTLQAETATKPQAT(0.002)S(0.002)APS(0.996)PAPK 68.458 0.00045203 9728900.0 35345.0 36043.0 37239.0 53741.0 52066.0 38652.0 38264.0 58085.0 48313.0 45951.0 True False 46583.97477832907 47693.19489071945 36745.186528469625 41351.84274017321 44837.53462457934 36235.084329776735 41669.42187280994 49109.29791051489 50866.72654705569 44342.269476395886 1.0505545911024352 1.0755695514436248 0.8286717608811088 0.9325603589637078 1.0111691429877556 0.8171680150260523 0.9397223544228211 1.1075052876275666 1.1471385463058645 1.0 15.4363949900468 -7.760412821192792 24.998450126010223 1.09549146842521 0.947360993912825 0.33421288171981145 0.08625715350999769 29.930595353147293 728925.1566505783 0.04487221720270676 0.023994826866906377 1.736149736727816e-08 7.760412821192792 -0.14813047451238492 APPTLQAETATKPQATSAPS(ph)PAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APPTLQAETATKPQATSAPSPAPK 24 1 A8CG34-2;A8CG34;Q96HA1;Q96HA1-2;Q96HA1-3 A8CG34-2;Q96HA1 POM121C;POM121 Nuclear envelope pore membrane protein POM 121C;Nuclear envelope pore membrane protein POM 121 1 APPT(0.002)LQAET(0.002)AT(0.004)KPQAT(0.293)S(0.085)APS(0.615)PAPK 45.511 0.024406 5241100.0 14383.0 13589.0 13923.0 12951.0 23550.0 16982.0 15031.0 16838.0 16281.0 14443.0 True False 16817.757822801068 14938.026113427662 14254.977123271534 12225.397457708514 18935.546555089513 16091.434024897575 13607.154864983848 16396.020341335698 16519.078824374108 17061.401569274913 0.9857195936989953 0.8755450748154748 0.8355103222552748 0.7165529401596563 1.1098470707816679 0.9431484253835214 0.7975402729801719 0.9610007873481233 0.9682134704643816 1.0 14.058448546368982 -6.254013085991881 24.985669463067957 0.9520469789697982 0.8536456718705283 0.24195014051173624 0.094095602738327 1022.9610258619421 3441737.10426438 0.029311993526180764 0.0370714423766326 5.571689602812751e-07 6.254013085991881 -0.09840130709926986 APQAGAHTPLTPQPGLAPQQQS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APQAGAHTPLTPQPGLAPQQQSPK 24 0 O15063 O15063 KIAA0355 Uncharacterized protein KIAA0355 1 APQAGAHTPLT(0.001)PQPGLAPQQQS(0.999)PK;APQAGAHTPLTPQPGLAPQQQS(1)PK 75.17399999999999 0.0014161 5054200.0 17164.6 17820.7 14880.0 19509.0 17925.6 14733.6 14286.8 15863.5 14602.2 11402.0 True False 20070.227763696803 19589.82132309666 15234.795632714258 18415.973979031376 14413.207359996297 13960.944078979548 12933.45087652526 15447.099933767608 14815.729550351656 13469.092341817663 1.4900950453346073 1.4544277243000179 1.13109296796597 1.3672765403690246 1.0700949250490643 1.036517066234287 0.9602318068880269 1.1468552996558499 1.0999798037135042 1.0 13.71736501297186 -5.151989422683552 0.6359171116767258 1.0426796242658523 1.6852994908302932 0.7391188336704598 0.09273050777420479 1.2070658166769344 0.5069827512820319 0.048094222399966934 0.5282773713283142 7.047102320964741e-06 5.151989422683552 0.6426198665644409 APQAGAHTPLTPQPGLAPQQQS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 APQAGAHTPLTPQPGLAPQQQSPK 24 0 O15063 O15063 KIAA0355 Uncharacterized protein KIAA0355 1 APQAGAHTPLTPQPGLAPQQQS(1)PK 166.98 3.1268000000000005e-10 3609800.0 29949.0 27198.0 20948.0 22742.0 25567.0 23473.0 24917.0 25624.0 24424.0 22495.0 True False 29521.921768026044 27135.024702040155 19225.73630161842 24414.52254508802 24063.199326655984 22469.114508235543 26207.080340182663 26814.58458501103 21673.111923877976 26383.23077729663 1.1189653768040542 1.028495142656693 0.7287104624867476 0.9253803202182984 0.9120641641569884 0.8516437845652598 0.9933233939921585 1.0163495445783535 0.8214730071090528 1.0 14.687333621204402 -5.010942473473 23.196932712389668 0.9067600183583521 1.0963480916430246 0.40566816127941585 0.0843187318991427 181.09916064131085 383929.3263936369 0.021135632171006103 0.0652413679031121 9.751187931289912e-06 5.010942473473 0.18958807328467253 APQPTSPPAS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 APQPTSPPASR 11 0 E7ET89;Q86UW9 E7ET89 DTX2 Probable E3 ubiquitin-protein ligase DTX2 1 APQPT(0.367)S(0.185)PPAS(0.449)R 92.19 0.0077822 4490600.0 15705.0 14053.0 15145.0 15301.0 13638.0 15315.0 13234.0 12503.0 16195.0 11545.0 True False 15481.043820055727 14020.461141913747 13899.836561390626 16426.28658263969 12835.839653339639 14660.013151008696 13919.191765540689 13083.935024445555 14370.94855908959 13540.537867254476 1.143310847163172 1.0354434424514174 1.0265350385382441 1.2131192086810607 0.9479564090567605 1.0826758356816448 1.0279644650750488 0.9662788253106889 1.0613277478321834 1.0 13.72499742739947 -6.288346486785105 24.998964311406265 1.0167764590061903 1.0940860644101833 0.3305269342314898 0.06214053357171286 1008.9117973438664 937360.5992422482 0.01893011688433357 0.021471917315120857 5.148177512131675e-07 6.288346486785105 0.07730960540399301 APQT(ph)SSSPPPVR ddPTM_PC-9_Lapatinib_30min_R1 1 APQTSSSPPPVR 12 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 APQT(0.52)S(0.262)S(0.073)S(0.146)PPPVR 95.273 0.011364 35199000.0 15421.0 11466.0 16874.0 11997.0 16374.0 18264.0 15443.0 13321.0 15560.0 12207.0 True False 15201.093712134942 11439.451181468936 15486.684855523648 12879.299400818794 15410.9135125226 17482.89129546346 16242.562976820667 13939.94229070137 13807.468945936027 14316.963685194925 1.0617540175682842 0.7990137736605698 1.0817017627514363 0.8995831577150112 1.07640934568123 1.2211312174761189 1.1344977422564109 0.9736661066701293 0.9644132128528228 1.0 13.80543794053286 -6.279973978088771 23.83621573898792 1.071982413758599 0.9576338370430595 0.1820693380279188 0.1036126919374006 721.4257041036901 927778.6583349103 0.03300804931578378 0.03750750094162883 5.248389064293876e-07 6.279973978088771 -0.11434857671553944 APQTS(ph)SSPPPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APQTSSSPPPVR 12 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 APQT(0.001)S(0.343)S(0.343)S(0.313)PPPVR 151.3 0.00018585 92547000.0 57227.0 53348.0 70505.0 55390.0 75426.0 62268.0 49262.0 52277.0 58878.0 46242.0 True False 66914.40081522895 58644.036875350575 72186.10659170157 52286.67787680289 60646.816750071455 59002.55646345082 44595.54673400532 50904.78414206004 59738.97936376745 54625.30854852941 1.22497067006554 1.0735689817340055 1.3214773245183788 0.9571877810145665 1.1102329371044652 1.0801322323155875 0.8163898368534872 0.9318900981005163 1.0936135822591286 1.0 15.737281903181927 -6.255615265785292 1.019244637999406 0.9665877768173994 1.1883254951237412 0.3740537849548565 0.10898253326533117 0.5740956911014695 1.2543007929804963 0.049519653074164026 0.07712116733843269 5.551172642931783e-07 6.255615265785292 0.2217377183063418 APQTS(ph)SSPPPVR ddPTM_PC-9_Lapatinib_30min_R1 3 APQTSSSPPPVR 12 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 APQT(0.064)S(0.705)S(0.212)S(0.019)PPPVR;APQT(0.038)S(0.321)S(0.321)S(0.321)PPPVR;APQT(0.03)S(0.323)S(0.323)S(0.323)PPPVR 123.95 0.00033685 165530000.0 121985.0 126653.0 151868.0 127654.0 157958.0 141886.0 129934.0 119593.0 143771.0 112787.0 True False 120245.471530691 126359.74276003723 139381.9992674329 137042.10100126048 148667.22099737654 135817.86653242056 136661.34674805525 125149.72737571142 127577.99600425259 132282.0826707691 0.9090080009547817 0.955229462742345 1.0536725492471604 1.0359838478075551 1.1238651372566282 1.0267291215126353 1.0331054968962463 0.9460822270782576 0.9644389733549608 1.0 17.013258139284233 -5.057060948563912 3.8420222664025037 1.0253898852858818 0.9154327429684012 0.3958158890852137 0.046346944003293845 0.23281629682735502 6.774946430841979 0.013335948984029978 0.04691189194380006 8.768777521379301e-06 5.057060948563912 -0.10995714231748066 APQTSS(ph)SPPPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APQTSSSPPPVR 12 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 APQT(0.095)S(0.098)S(0.404)S(0.404)PPPVR;APQT(0.011)S(0.128)S(0.43)S(0.43)PPPVR 129.76 0.00016585 161166000.0 86814.0 105807.0 109146.0 104483.0 131035.0 112775.0 99268.0 108232.0 96553.0 75301.0 True False 101509.89554534203 116310.81970589756 111748.4545785098 98629.15624845614 105359.6323926183 106860.88047095877 89864.61640191701 105391.02468128304 97964.90496466991 88952.47521761195 1.1411699932689878 1.3075613626417544 1.2562714450062251 1.1087848427733047 1.1844485736329218 1.2013255416393527 1.0102542529825462 1.1848014844270054 1.1013173576677895 1.0 16.440747130454923 -7.494403003274702 0.18441998843727014 0.9501398948341129 1.3161349272752634 0.45178546381447715 0.06919029296550817 3.5461374853103003 0.5471163982021437 0.36952741529802957 0.5133588817280502 3.203295449041424e-08 7.494403003274702 0.3659950324411505 APQTSSS(ph)PPPVR ddPTM_PC-9_AZD4547_30min_R2 7 APQTSSSPPPVR 12 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 APQT(0.044)S(0.165)S(0.165)S(0.626)PPPVR;APQTS(0.003)S(0.027)S(0.97)PPPVR;APQT(0.023)S(0.078)S(0.033)S(0.866)PPPVR;APQT(0.001)S(0.017)S(0.064)S(0.918)PPPVR;APQT(0.134)S(0.056)S(0.187)S(0.622)PPPVR;APQT(0.092)S(0.092)S(0.092)S(0.725)PPPVR;APQT(0.156)S(0.156)S(0.156)S(0.531)PPPVR 193.45 1.7986e-05 1330362500.0 453380.39999999997 429589.10000000003 631062.0 855250.0 721426.0 633391.0 532820.5 671449.0 538729.6000000001 609791.0 True False 597545.9363018464 568445.3755022823 622693.7055514135 658085.325980781 621268.4526192102 593784.9606416649 580240.4922899202 567691.9854130546 567205.7468177233 588442.4026959358 1.0154705601843153 0.9660170186546082 1.0582067211651576 1.1183512999161476 1.0557846439564562 1.0090791518783355 0.9860616597844772 0.9647367062811694 0.9639103916017655 1.0 19.166541684243377 -7.079071737081195 2.7173343672465347 0.9751294035280997 1.0431349819003048 0.3955767273564227 0.037146944322803924 0.32601613722462996 4.716045251860659 0.01781836892959673 0.01358990898078601 8.335434879225585e-08 7.079071737081195 0.06800557837220511 APQTSSS(ph)PPPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 APQTSSSPPPVR 12 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 APQT(0.08)S(0.08)S(0.26)S(0.581)PPPVR;APQT(0.026)S(0.303)S(0.303)S(0.368)PPPVR;APQT(0.008)S(0.033)S(0.032)S(0.927)PPPVR;APQT(0.004)S(0.049)S(0.402)S(0.545)PPPVR 180.3 6.5367e-05 943745000.0 391494.0 440373.0 505745.0 460849.0 527758.0 467736.0 490000.0 424737.0 443774.0 372076.6 True False 457766.2018410406 484090.32111623324 517803.8788485927 435029.1246226172 424347.60844250314 443207.1007578309 443583.6527072112 413588.10379605007 450263.3552120744 439531.1422232547 1.0414875258338887 1.1013788890306782 1.1780823452677678 0.9897572272629757 0.9654551581852663 1.008363363096372 1.0092200758823549 0.9409756535202978 1.0244174120052871 1.0 18.745605863103194 -5.78643170320221 24.992992289477506 0.9891074924762041 1.106422497292128 0.6615494728911762 0.03793994815770507 124.52680037184172 124529.66595616454 0.010655763603553864 0.01581238531769268 1.6351902796077908e-06 5.78643170320221 0.11731500481592383 APQTSSS(ph)PPPVR ddPTM_PC-9_Lapatinib_30min_R1 3 APQTSSSPPPVR 12 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 APQT(0.007)S(0.031)S(0.088)S(0.874)PPPVR;APQT(0.003)S(0.011)S(0.037)S(0.948)PPPVR;APQT(0.033)S(0.033)S(0.22)S(0.715)PPPVR 165.51 0.00018325 1021723600.0 461997.2 382679.4 465324.0 394036.2 452679.3 447750.0 412303.8 410202.4 457177.0 355033.7 True False 455409.03520809044 381793.32936105237 427066.8569225846 423014.93661423016 426053.59357574634 428600.77625622856 433650.8733460132 429261.9010214842 405684.91197276313 416400.8019923305 1.093679534307137 0.9168890346375568 1.02561487605024 1.0158840583165387 1.0231814913353448 1.0292986329649834 1.0414266045385772 1.030886345481608 0.974265443370196 1.0 18.667613321722662 -4.454227992122016 22.605934739430666 1.0102705703612036 4.066636938867293 0.35315215534139544 0.03509044284711376 504.41921691116886 179695.9775062375 0.008363993548505718 6389.322018045639 3.5137592983599255e-05 4.454227992122016 3.0563663685060893 APQTSSS(ph)PPPVRR ddPTM_PC-9_AZD4547_30min_R2 3 APQTSSSPPPVRR 13 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 APQTS(0.014)S(0.04)S(0.946)PPPVRR;APQT(0.004)S(0.039)S(0.065)S(0.892)PPPVRR;APQT(0.001)S(0.008)S(0.008)S(0.984)PPPVRR 99.568 0.0036341999999999998 159414000.0 53509.4 45786.6 69894.0 101677.0 94676.0 63429.0 56898.6 74329.0 53270.9 71807.0 True False 70524.27613533795 60586.22304423646 68967.15989207165 78236.93854399047 81531.87162671745 59462.774602954814 61962.465172806376 62843.160960500405 56086.6910193022 69293.0587863498 1.017768263813903 0.8743476490342419 0.9952968031721189 1.129073242173032 1.1766239368665106 0.8581346478915797 0.8942088321408105 0.9069185580948843 0.8094128329972187 1.0 16.08042322172352 -6.799184008761468 24.999716667315003 0.8879469035661083 1.0321140029893945 0.4043605778864017 0.08760549856202006 189.58874463879633 125570.67594467891 0.033545900190845246 0.029585339771929998 1.5878738305291882e-07 6.799184008761468 0.1441670994232862 APQTSSS(ph)PPPVRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 APQTSSSPPPVRR 13 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 APQT(0.001)S(0.004)S(0.018)S(0.977)PPPVRR;APQT(0.002)S(0.017)S(0.035)S(0.946)PPPVRR;APQT(0.025)S(0.019)S(0.054)S(0.902)PPPVRR 101.75 0.0028245 126150000.0 53583.2 46034.8 47578.0 64787.0 69158.4 63974.0 59921.8 62218.0 52322.1 48653.5 True False 62653.77744355934 50604.83071060564 48712.43996056981 61157.194432287935 55607.30797772835 60619.09082020947 54245.573307736595 60584.84342542014 53087.21172881172 57473.99440910592 1.0901239436671684 0.8804822290651168 0.8475561940906622 1.0640846362089367 0.967521198925373 1.054722078105733 0.943828141152169 1.0541262017421458 0.9236736070740339 1.0 15.81062169867146 -5.774004943954732 24.999239144358985 1.0018360356618023 0.9334969047210216 0.12601272596953905 0.0740200374903073 407.26463400137453 810254.1394424732 0.0201493383133363 0.03011555235099861 1.6826549058258544e-06 5.774004943954732 -0.0683391309407807 APQTSSS(ph)PPPVRR ddPTM_PC-9_Lapatinib_30min_R1 2 APQTSSSPPPVRR 13 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 APQT(0.013)S(0.044)S(0.044)S(0.898)PPPVRR;APQT(0.005)S(0.005)S(0.005)S(0.985)PPPVRR 96.756 0.0046764 121799000.0 69739.0 49249.0 54469.0 49372.0 57472.0 58811.0 46962.0 41711.0 68687.0 41873.0 True False 68744.50907143365 49134.96696634954 49990.76907642037 53002.981580163876 54091.60995429939 56295.790625136964 49393.46257316921 43649.04533349186 60950.74675382439 49110.69225773466 1.399787009937877 1.0004942856127435 1.0179202690539777 1.0792554359039033 1.1014222660602033 1.1463041557161249 1.0057578157104883 0.8887890462716369 1.2410891386737677 1.0 15.5837495382619 -4.756187623746639 24.999589365625006 1.0525795610595616 1.3997875516248452 0.5649859667622318 0.09116784681504972 121.51933791216729 578397.404398951 0.02218022314485411 0.18350767035902002 1.7531229546644776e-05 4.756187623746639 0.3472079905652836 APRPFGSVS(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APRPFGSVSSPK 12 1 Q96HC4;A0A0D9SFR4 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 1 APRPFGSVS(0.741)S(0.259)PK 59.75 0.029643 46514000.0 68546.0 55453.0 51836.0 72546.0 92634.0 72037.0 80984.0 83414.0 60065.0 63664.0 True False 80149.48395478852 60958.00736389025 53071.96682912472 68481.48281730551 74483.03267873287 68259.25290610925 73312.60924661378 81224.47088443853 60943.336993184086 75205.7792360532 1.0657357023483287 0.8105495080711476 0.7056900063829448 0.910588036091725 0.9903897471090379 0.9076330781954876 0.9748268017608432 1.080029642795058 0.8103544383457197 1.0 16.198555910532534 -5.996340714827536 24.99821796703114 0.9615076652725513 0.8477294338660183 0.15026263020512431 0.10553423194360233 183.73370131210322 1255138.2207473866 0.02960465612604831 0.04368290510397185 1.0084614125803937e-06 5.996340714827536 -0.11377823140653298 APRPFGSVS(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 1 APRPFGSVSSPK 12 1 Q96HC4;A0A0D9SFR4 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 1 APRPFGS(0.004)VS(0.666)S(0.33)PK 87.21600000000001 0.041985 11299000.0 46485.0 37898.0 35928.0 39285.0 37073.0 34607.0 34389.0 33023.0 34796.0 36589.0 True False 45822.11537569502 37810.24950944617 32974.13852609062 42174.14995091827 34892.43902832235 33126.939282857194 36169.494153330685 34557.36913638853 30876.908061875944 42913.3598982221 1.067782049328499 0.8810834108333859 0.7683886464330828 0.9827743632971871 0.8130903548703009 0.7719493267696721 0.8428492720941476 0.8052822994598529 0.7195173748945995 1.0 15.38913924075549 -4.788260861299628 3.5113198242345707 0.8325634318804636 1.094241940164615 0.39223374550599754 0.08518042374025918 0.27325713664056533 5.59556975436157 0.020752711519320743 0.18929098044811693 1.628317681132943e-05 4.788260861299628 0.2616785082841515 APRPFGSVSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 APRPFGSVSSPK 12 1 Q96HC4;A0A0D9SFR4 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 1 APRPFGSVS(0.004)S(0.996)PK 110.8 0.005547 10009000.0 62749.0 51529.0 46882.0 51363.0 45289.0 44895.0 43946.0 35646.0 43686.0 45487.0 True False 61854.187753242695 51409.687766432326 43027.54292975344 55140.406361945155 42625.190061599846 42974.94550535655 46221.30885057057 37302.243292120824 38765.62264602577 53349.36734238233 1.1594174558112122 0.9636419385538043 0.8065239584494769 1.0335718886424352 0.7989821095354794 0.8055380531423091 0.8663890717566388 0.6992068538081202 0.7266369701675769 1.0 15.703183542118934 -1.522878745286111 0.5630732205194598 0.8086905050243753 17.38783719920117 0.4857487629346561 0.10054794512594004 118.58264442059877 1.0414202522407647 0.048157981837411205 2389.4414308276187 0.029999999999601186 1.522878745286111 16.579146694176792 APRPS(ph)APSPPPR ddPTM_PC-9_AZD4547_30min_R2 1 APRPSAPSPPPR 12 1 Q8IV50 Q8IV50 LYSMD2 LysM and putative peptidoglycan-binding domain-containing protein 2 1 APRPS(0.953)APS(0.047)PPPR 74.69800000000001 0.0096969 7734300.0 6131.6 5724.8 11934.0 12487.0 11140.0 10239.0 10805.0 9459.6 9918.6 8737.7 True False 8081.321254797073 7575.229645434363 11775.74736246292 9608.315072226847 9593.403290397064 9598.7537113884 11766.624067941439 7997.8361799829045 10442.876946776774 8431.795782548894 0.9584341773934812 0.8984123715511058 1.3965883029134707 1.1395336557027353 1.137765137795714 1.1383996907580154 1.395506292063497 0.9485329562340509 1.2385116072652247 1.0 13.041624210096439 -5.22631838988649 24.97059590672015 1.17658041184422 0.9284231367449146 0.3379590274525539 0.13765608276319652 641.5990710886972 456167.25524834835 0.03318740376071837 0.08779808714727615 5.938566309298009e-06 5.22631838988649 -0.2481572750993054 APRPS(ph)APSPPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APRPSAPSPPPR 12 1 Q8IV50 Q8IV50 LYSMD2 LysM and putative peptidoglycan-binding domain-containing protein 2 1 APRPS(0.938)APS(0.062)PPPR 72.73100000000001 0.011482 8992900.0 18232.0 18251.0 26753.0 28146.0 25687.0 24833.0 21502.0 17999.0 19631.0 18924.0 True False 21318.31750158582 20062.83866334303 27390.8929813175 26569.070870563184 20653.816745672386 23530.71376400195 19465.174899000893 17526.545321516885 19918.066236796752 22354.77139769843 0.9536361218965845 0.8974745617577029 1.2252817304200914 1.1885190144820108 0.9239108903524207 1.0526036408685704 0.8707391613499103 0.7840180966163384 0.8909984308248148 1.0 14.448295172350464 -7.263900399484056 22.77750242807555 0.8684403907995729 1.0436120154395652 0.31088715524623467 0.1108206457633247 76.1138056876056 704439.192866024 0.04757189450041498 0.03383507747667713 5.4462754267345545e-08 7.263900399484056 0.17517162463999225 APRPSAPS(ph)PPPR ddPTM_PC-9_AZD4547_30min_R2 1 APRPSAPSPPPR 12 1 Q8IV50 Q8IV50 LYSMD2 LysM and putative peptidoglycan-binding domain-containing protein 2 1 APRPS(0.374)APS(0.626)PPPR 69.878 0.014674000000000001 36237000.0 65280.0 87942.0 76279.0 132410.0 144660.0 124700.0 77958.0 125060.0 101240.0 81499.0 True False 86037.68209164863 116367.531700459 75267.49062018687 101884.92021410723 124576.4560133607 116902.48928705294 84896.11097534273 105734.85059290694 106591.33971444375 78645.74481636487 1.0939903016055565 1.479641803535248 0.9570446665097253 1.295491834326257 1.5840202963840253 1.4864439209014584 1.0794749439219153 1.344444646557728 1.3553351165194112 1.0 16.263081089266684 -10.890019274711356 3.376779055384436 0.9978131422684747 1.3015948442763752 0.1800582136466934 0.19014392647359685 35241033.25591288 47125138.60720419 750755.0054398575 0.04962806865803262 1.2881923783043524e-11 10.890019274711356 0.30378170200790044 APRPSAPS(ph)PPPR ddPTM_PC-9_Lapatinib_30min_R1 2 APRPSAPSPPPR 12 1 Q8IV50 Q8IV50 LYSMD2 LysM and putative peptidoglycan-binding domain-containing protein 2 1 APRPS(0.366)APS(0.634)PPPR;APRPS(0.006)APS(0.994)PPPR 72.523 0.011715 85341000.0 110894.0 105422.0 99084.0 101347.3 83265.0 84613.8 91914.0 78885.2 101384.0 70495.0 True False 109312.63122453085 105177.90183610845 90937.69599530066 108800.71852668216 78367.5164052885 80995.06501840166 96672.85718134405 82550.49437658089 89965.06629915023 82679.96682131689 1.3221175023058598 1.2721086604136256 1.099875816252199 1.3159260061366003 0.9478416527990606 0.9796214020434171 1.169241605893091 0.9984340530153355 1.0881120271078177 1.0 16.33525018937315 -5.634319252612248 0.8864805856124314 1.0386456153423556 1.3281105650315914 0.5204499553352252 0.0941234906064063 0.716249968868629 0.9536517853075113 0.03922595477989094 0.15809598309592762 2.3210299653192387e-06 5.634319252612248 0.28946494968923586 APS(ph)APPGTGALPPAAPSGR ddPTM_PC-9_AZD4547_30min_R2 4 APSAPPGTGALPPAAPSGR 19 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 APS(1)APPGTGALPPAAPSGR;APS(1)APPGTGALPPAAPSGR;APS(0.999)APPGT(0.001)GALPPAAPSGR;APS(0.964)APPGT(0.036)GALPPAAPSGR 135.95 3.9374e-05 25759000.0 86963.9 82123.8 102957.7 130837.8 115026.6 125185.7 104102.8 144495.5 118559.1 122403.20000000001 True False 114616.61123851 108668.7123315613 101592.413626634 100675.16663385944 99057.14209364346 117357.81838927204 113367.74752615423 122167.04065126642 124825.89198280008 118117.90122463464 0.9703576684835777 0.9200020590011752 0.8600932845346385 0.8523277639550765 0.838629378499185 0.9935650496031326 0.9597846418770458 1.0342804891100392 1.056790636208548 1.0 16.849868101753522 -6.858237465606209 6.175082853030785 1.0099205155006392 0.8867719539063244 0.6720939375121009 0.04220480584365335 0.14247327575202787 7.628411160963977 0.0165516530425159 0.01462378482760692 1.385997779175848e-07 6.858237465606209 -0.12314856159431486 APS(ph)APPGTGALPPAAPSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 APSAPPGTGALPPAAPSGR 19 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 APS(1)APPGTGALPPAAPSGR;APS(0.994)APPGT(0.006)GALPPAAPSGR;APS(1)APPGTGALPPAAPSGR;APS(0.971)APPGT(0.029)GALPPAAPSGR;APS(0.983)APPGT(0.01)GALPPAAPS(0.007)GR 161.1 5.1372000000000006e-06 47975400.0 249111.1 275200.2 281582.5 303599.6 337130.2 276333.8 306967.9 243069.1 269331.2 225915.2 True False 291280.68906150176 302520.2571212386 288296.4947075785 286589.8986951836 271071.95741939027 261842.36907014696 277889.6782568612 236688.79367800037 273269.65927542996 266871.83741626056 1.0914628230597776 1.1335787996594577 1.0802806976515107 1.0738858827136837 1.015738341084595 0.9811539936367705 1.0412851387664983 0.8869006035613215 1.0239733870801444 1.0 18.025787542510784 -6.224558807361214 1.1196867005487738 0.9778477451974965 1.1133334123781484 0.6253507578479922 0.040142268729784686 0.3003044420004871 0.7794983965078087 0.016270238742861102 0.025299934904882245 5.962675743992918e-07 6.224558807361214 0.13548566718065191 APS(ph)APPGTGALPPAAPSGR ddPTM_PC-9_Lapatinib_30min_R1 2 APSAPPGTGALPPAAPSGR 19 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 APS(0.996)APPGT(0.004)GALPPAAPSGR;APS(1)APPGTGALPPAAPSGR 150.9 7.5048e-05 29124400.0 42001.0 50562.0 37105.0 39814.0 47759.0 50659.0 38347.0 41839.0 40219.0 36789.0 True False 41402.05803795994 50444.92679552005 34054.37012944202 42742.05437561055 44949.909517806685 48492.432661896826 40332.42002668798 43782.99268077885 35689.11269515432 43147.92963173884 0.9595375349714423 1.1691158121851961 0.7892469098770438 0.9905934013614933 1.0417628354696846 1.1238646460159856 0.9347475156031628 1.01471827395799 0.8271338393233599 1.0 15.397003715739716 -8.219208229796937 24.924918824543695 0.913566720350502 1.0040030790581391 0.10304742110039922 0.10544407790660389 926.0837478664778 546578.0254148473 0.06977367140365137 0.02637162012700414 6.036591254530874e-09 8.219208229796937 0.09043635870763711 APS(ph)ASPLALHASR ddPTM_PC-9_AZD4547_30min_R2 1 APSASPLALHASR 13 0 H0Y6J8;Q8N3F8 H0Y6J8;Q8N3F8 MICALL1 MICAL-like protein 1 1 APS(0.508)AS(0.484)PLALHAS(0.008)R 90.689 0.0054859999999999996 4789100.0 0.0 0.0 7909.6 17327.0 12608.0 6888.4 2135.2 11098.0 2840.2 8616.5 True False 0.0 0.0 7804.713535959173 13332.527849481425 10857.59682992156 6457.667259061215 2325.228663569509 9383.059106669436 2990.32717361678 8314.838957658483 0.0 0.0 0.9386487911194656 1.6034619452492629 1.3058096356660087 0.7766436959206892 0.2796480696030594 1.128471537987763 0.3596374131651104 1.0 13.021472606233873 -5.261425992152414 24.999690479371623 0.9382499534198614 3.752508752427007e-05 0.49140649116197677 0.37580182161224834 0.9916557180850448 1846426.5556086795 0.10481493601553174 0.24357777004186013 5.4773943293918505e-06 5.261425992152414 -0.9382124283323371 APS(ph)DSS(ph)LGTPSDGRPELR ddPTM_PC-9_AZD4547_30min_R2 1 APSDSSLGTPSDGRPELR 18 1 Q15642;M0R2H7;M0R0F9;W4VSQ9;Q15642-5;Q15642-4;Q15642-2;Q15642-3 Q15642 TRIP10 Cdc42-interacting protein 4 2 APS(1)DS(0.256)S(0.719)LGT(0.024)PS(0.002)DGRPELR 106.28 0.009622799999999999 4341200.0 7100.3 8659.8 12285.0 20665.0 16109.0 14263.0 12040.0 15852.0 14443.0 15423.0 True False 9358.047704585379 11458.910998381161 12122.092873123589 15901.003521067332 13872.543411580458 13371.132355262494 13111.536675429428 13402.437642721572 15206.427494031113 14883.04546439585 0.6287723656406402 0.7699305243536266 0.814490078802945 1.0683971609914589 0.9321038120032101 0.8984137277044374 0.8809713513807147 0.9005171471647869 1.021728216204733 1.0 13.861382149733249 -5.200508531240722 1.791621583493464 0.9451031422611168 0.6391089132009335 0.7234883935445697 0.06475532858191953 0.24618929656213134 1.3230437030310467 0.018892369725023526 0.09556143121607619 6.302189659060515e-06 5.200508531240722 -0.30599422906018325 APS(ph)DSSLGTPS(ph)DGRPELR ddPTM_PC-9_Lapatinib_30min_R1 1 APSDSSLGTPSDGRPELR 18 1 Q15642;M0R2H7;M0R0F9;W4VSQ9;Q15642-5;Q15642-4;Q15642-2;Q15642-3 Q15642 TRIP10 Cdc42-interacting protein 4 2 APS(0.969)DS(0.112)S(0.092)LGT(0.008)PS(0.818)DGRPELR 99.413 0.019397 5511400.0 54815.0 55224.0 63061.0 56148.0 63592.0 56289.0 49830.0 48940.0 64996.0 55720.0 True False 54033.32804816014 55096.13222095244 57876.36800249949 60277.3112242372 59851.643586682316 53881.65068606786 52409.95357993745 51213.93106425383 57675.46604177751 65351.12775776694 0.8268155409412703 0.843078522304526 0.8856215644361382 0.9223606889794381 0.9158471420498017 0.8244945808094958 0.801974738281522 0.7836732558630879 0.8825473717234026 1.0 15.995924512226608 -6.7808444900737355 24.976816487308586 0.8414823649552906 0.8795684110247647 0.0 0.06269278629753582 678.7189292469942 873590.6992434467 0.021866008896947616 0.01931104105587769 1.656362959193099e-07 6.7808444900737355 0.03808604606947408 APS(ph)DSSLGTPSDGRPELR ddPTM_PC-9_AZD4547_30min_R2 1 APSDSSLGTPSDGRPELR 18 1 Q15642;M0R2H7;M0R0F9;W4VSQ9;Q15642-5;Q15642-4;Q15642-2;Q15642-3 Q15642 TRIP10 Cdc42-interacting protein 4 1 APS(0.972)DS(0.013)S(0.015)LGTPSDGRPELR 114.56 6.6077e-05 110780000.0 65108.0 72268.0 85891.0 155660.0 125800.0 135750.0 86831.0 95030.0 79366.0 102310.0 True False 85810.98966947092 95627.21772223497 84752.02921981763 119774.99192302642 108334.84146606382 127261.53104023551 94558.79078606406 80345.29707215693 83561.12473109976 98728.1580407404 0.8691642928662846 0.9685911255710269 0.8584382703143769 1.2131796470222913 1.0973043923432584 1.2890094737483175 0.9577692186563853 0.8138032620744556 0.8463758099955443 1.0 16.591173990797706 -7.520356539371883 24.537276122033195 0.875210909429183 1.0529730691103691 0.22731856286078456 0.13500705312742903 120.7698356088204 1174959.4310867134 0.06669569970383392 0.039407414440536824 3.017473471478188e-08 7.520356539371883 0.17776215968118614 APS(ph)DSSLGTPSDGRPELR ddPTM_PC-9_Lapatinib_30min_R1 2 APSDSSLGTPSDGRPELR 18 1 Q15642;M0R2H7;M0R0F9;W4VSQ9;Q15642-5;Q15642-4;Q15642-2;Q15642-3 Q15642 TRIP10 Cdc42-interacting protein 4 1 APS(0.507)DS(0.217)S(0.217)LGT(0.057)PS(0.002)DGRPELR;APS(0.278)DS(0.228)S(0.203)LGT(0.047)PS(0.245)DGRPELR 69.612 0.0051087 13783200.0 23126.1 17482.9 28669.0 19175.1 25779.8 21795.2 20616.9 20177.4 25817.4 22393.0 True False 22796.317573192675 17442.419419196172 26311.945485540324 20585.300820258453 24263.482849036885 20863.070103092723 21684.342202733547 21114.915665220167 22909.572542725487 26263.60021320307 0.8679814415440521 0.664129033247606 1.0018407709508519 0.7837958487469643 0.9238445092093391 0.7943720561434899 0.825642411044337 0.8039612046259146 0.872293682387403 1.0 14.68077707391127 -8.621313703692422 5.205643537796841 0.9999949239245642 0.8331805574812661 0.2603810876205477 0.08444938540046448 1.1635060892303877 60.17909446385207 0.07623284262266913 0.01980804355445505 2.3915876181791684e-09 8.621313703692422 -0.16681436644329817 APS(ph)EEEALEK ddPTM_PC-9_AZD4547_30min_R2 2 APSEEEALEK 10 0 Q14147 Q14147 DHX34 Probable ATP-dependent RNA helicase DHX34 1 APS(1)EEEALEK;APS(1)EEEALEK 105.25 0.0024872 6138900.0 19004.8 26104.0 28341.0 24441.0 22120.0 31357.0 25090.0 32569.0 27385.0 24358.0 True False 25047.931075603028 34541.607508457695 27965.179822319555 18806.50505968579 19049.019818993103 29396.241832992073 27322.96139422957 27536.209411165702 28832.51519241445 23505.233833998183 1.0656320737968357 1.4695283506814725 1.1897426768786477 0.8000986160147827 0.8104160951353918 1.2506253730806576 1.1624203182658575 1.1714926814017514 1.2266423468083452 1.0 14.520694412324092 -5.5281321663161345 24.97926205525802 1.0634569994304122 1.2830940771483785 0.19346395959971008 0.17395070972447182 211.0020129023184 1003281.0077365368 0.05037639315789997 0.08761797544286946 2.963929256892587e-06 5.5281321663161345 0.21963707771796637 APS(ph)EEEALEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APSEEEALEK 10 0 Q14147 Q14147 DHX34 Probable ATP-dependent RNA helicase DHX34 1 APS(1)EEEALEK;APS(1)EEEALEK 103.43 0.0028334 4210900.0 15139.099999999999 24000.0 17516.800000000003 15872.4 22754.8 13342.9 21378.0 11879.1 11336.0 13975.0 True False 17701.85061914535 26382.56138952565 17934.46694483395 14983.120887015095 18296.160286698545 12643.174835166992 19352.921076683153 11567.28621194684 11501.767554394979 16508.55687396086 1.0722833470117963 1.5981143349446354 1.0863739987546817 0.907597254042729 1.1082834451482124 0.7658558486786461 1.1722963566372504 0.7006842754494219 0.6967155059166226 1.0 14.010926389456712 -5.506417534913227 5.034869497807102 0.9125381981463818 1.341182476898211 0.4420389499167694 0.19125876034486394 0.1539098230860947 11.103860324136416 0.05023615197919628 0.09970585613915543 3.1158924944438116e-06 5.506417534913227 0.4286442787518292 APS(ph)EEEALEK ddPTM_PC-9_Lapatinib_30min_R1 2 APSEEEALEK 10 0 Q14147 Q14147 DHX34 Probable ATP-dependent RNA helicase DHX34 1 APS(1)EEEALEK;APS(1)EEEALEK 103.88 0.0026849 6443300.0 10335.6 23388.7 21186.6 21297.2 27567.0 20546.4 29292.0 28455.0 24133.0 23604.9 True False 10188.212448683093 23334.544902147456 19444.71953064106 22863.467133376525 25945.563258807277 19667.678367997734 30808.59643314323 29777.123180084644 21414.88740824383 27684.975513447822 0.3680051096210732 0.8428595102355366 0.70235639259265 0.8258438632994537 0.9371712554415793 0.7104098162717994 1.1128272957358452 1.0755697856991266 0.7735201859883051 1.0 14.7568156253967 -4.422880678887944 0.559711635994042 0.9582586911000825 1.0306581483827432e-19 0.5559655132247977 0.1378336479437127 4.64622581081073 0.8277035399665674 0.0731503473434472 3.1549167716720845 3.7767594200940174e-05 4.422880678887944 -0.9582586911000825 APS(ph)EIDPR ddPTM_PC-9_AZD4547_30min_R2 2 APSEIDPR 8 0 O95801 O95801 TTC4 Tetratricopeptide repeat protein 4 1 APS(1)EIDPR;APS(1)EIDPR 97.635 0.0057526 97476000.0 146261.0 151090.0 197984.0 284150.0 264350.0 238440.0 155607.0 243280.0 200419.0 210500.0 True False 192768.95558220946 199926.8877740143 195358.60279955226 218643.60757373716 227649.56551314812 223530.30910669497 169455.72154929797 205686.66601825046 211012.73917650228 203130.45907121358 0.9489908921764826 0.9842289959278033 0.961739582004604 1.0763703709106716 1.1207062030679438 1.100427331916429 0.8342211321931297 1.0125840652294333 1.0388040284127222 1.0 17.63204705999025 -5.725663406132337 24.97153657002083 1.0257199461587938 0.9669106581431074 0.12387001859225188 0.07449422321786026 439.0396195660231 306445.442967675 0.022081249907134136 0.0382440397438282 1.8807739196138274e-06 5.725663406132337 -0.05880928801568641 APS(ph)EIDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APSEIDPR 8 0 O95801 O95801 TTC4 Tetratricopeptide repeat protein 4 1 APS(1)EIDPR;APS(1)EIDPR 96.03399999999999 0.006243899999999999 74076000.0 282371.0 290271.0 341897.0 331192.0 453263.0 355370.0 306394.0 348865.0 291975.0 215316.0 True False 330170.8332185325 319087.18654579134 350049.1211315938 312636.38597895106 364449.36892567057 336733.7716068687 277370.1422195368 339707.6634030217 296244.5820125691 254351.08635948208 1.2980909102620937 1.2545147383204638 1.3762438609633412 1.2291529415254496 1.4328594941032933 1.3238935851484932 1.090501110844564 1.3355856594333653 1.1647073588428778 1.0 17.95646173054846 -8.876521407232657 0.5420026447418271 0.9896998543519266 1.3148276350933061 0.5347172728648212 0.08631929661068821 1.1916504076777639 0.6965464564762686 0.11327131915710864 0.041697159209864 1.3288580534745853e-09 8.876521407232657 0.3251277807413795 APS(ph)EIDPR ddPTM_PC-9_Lapatinib_30min_R1 3 APSEIDPR 8 0 O95801 O95801 TTC4 Tetratricopeptide repeat protein 4 1 APS(1)EIDPR;APS(1)EIDPR;APS(1)EIDPR 104.01 0.0038649 112572000.0 403590.0 289101.0 386920.0 365405.0 356478.0 295849.0 299562.0 247424.0 396610.0 264695.0 True False 397834.7325906592 288431.604396812 355108.9311543919 392278.1026553457 335510.6649027135 283196.22792770324 315071.85459187656 258920.22230571962 351939.60531154805 310447.17806608323 1.2814892860967615 0.9290843169958372 1.1438626479600396 1.2635904925888666 1.0807334986671875 0.9122203322699257 1.0148968225596462 0.8340234365106861 1.133653742655804 1.0 18.243988292238818 -6.572695668170258 6.1264031950902345 0.97219244702381 1.1418493193833272 0.3417643383245432 0.11446981379359535 0.22786325556838918 19.397120505786493 0.03699715735419429 0.03720456387176788 2.6748801741729187e-07 6.572695668170258 0.1696568723595172 APS(ph)IDGKEELDLAEK ddPTM_PC-9_Lapatinib_30min_R1 1 APSIDGKEELDLAEK 15 1 Q9H0E9-3;H7C128;H7C179;H7C127;Q9H0E9-4;Q9H0E9-2;H0YA84;H0YAH7;B5MCW3;Q9H0E9 Q9H0E9-3 BRD8 Bromodomain-containing protein 8 1 APS(1)IDGKEELDLAEK 61.657 0.021773 9139500.0 22435.0 23504.0 21899.0 21829.0 21795.0 26197.0 24113.0 21710.0 24098.0 26524.0 True False 22115.072785924873 23449.577932081465 20098.548752584582 23434.377479409322 20513.060950618656 25076.615378189686 25361.45315418487 22718.725856251538 21383.829476810177 31108.638058991583 0.7108981352378033 0.7537963535277188 0.6460761385461983 0.7533077287077148 0.659400804102049 0.8060981432435802 0.8152543710236277 0.7303028121375748 0.6873920174923709 1.0 14.925027614391231 -6.775680514769676 24.956384024350278 0.7914187169108609 0.7068676472476997 0.2671428901748485 0.08316876338513245 380.055275720084 666010.2959928954 0.028048140287555676 0.024851171635710344 1.6761754875591212e-07 6.775680514769676 -0.08455106966316117 APS(ph)LDIKGPEVDVSGPK ddPTM_PC-9_Lapatinib_30min_R1 2 APSLDIKGPEVDVSGPK 17 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 APS(1)LDIKGPEVDVSGPK;APS(1)LDIKGPEVDVSGPK 78.708 0.014679 0.0 43187.0 57866.0 45955.0 53705.0 48788.0 36799.0 37645.0 33260.0 43347.0 58579.0 True False 42571.145460474174 57732.01483227644 42176.75729142995 57654.64485462812 45918.38576089854 35225.192552658766 39594.07390160033 34805.38102159954 38464.804395854044 68704.30209838897 0.6196285263113445 0.8402969402061677 0.6138881555194335 0.8391708101781307 0.6683480416574272 0.5127072319607298 0.5762968648586092 0.5065968208476377 0.5598602011962799 1.0 16.068112819519833 -10.861752053521288 3.93024278166802 1.000905767069117 0.6402260483220045 0.48377105310705704 0.11232969240245894 31973683.005042102 29456501.12752788 221788.489976111 0.029501436134330414 1.3748266640995259e-11 10.861752053521288 -0.3606797187471126 APS(ph)LTDLVK ddPTM_PC-9_AZD4547_30min_R2 2 APSLTDLVK 9 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 APS(0.994)LT(0.006)DLVK;APS(1)LTDLVK 87.184 0.011086 4842400.0 15133.2 14511.0 24952.0 36533.0 33979.0 30824.0 22194.0 29721.0 26677.0 28994.0 True False 19945.242809885687 19201.396971928796 24621.12017665282 28110.881279223475 29261.60237023358 28896.570407250314 24169.223004524967 25128.30237063636 28087.09175782508 27978.928885086756 0.7128665608252374 0.6862806310703147 0.8799879465641838 1.004716134583946 1.0458442669630041 1.0327975930005195 0.8638366073194308 0.898115237857807 1.00386586896098 1.0 14.772053112539881 -5.411674044515905 3.1127088752311765 0.9738012084060056 0.6973651238975404 0.800413925289512 0.054973867762886645 0.11894288973209045 2.1614722508471917 0.016939839668185085 0.04030410211361433 3.87548406467329e-06 5.411674044515905 -0.27643608450846524 APS(ph)LTDLVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APSLTDLVK 9 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 APS(0.999)LT(0.001)DLVK;APS(0.985)LT(0.015)DLVK 125.23 0.0014334 11460800.0 31880.0 30758.0 49696.0 59147.0 73129.0 72525.0 69178.0 58080.0 53578.0 62652.0 True False 37276.6543412986 33811.45096745957 50880.941113129535 55833.185347161285 58799.89741091902 68721.66132703431 62624.95903465183 56555.46154084673 54361.476890382386 74010.3116470408 0.5036683877116069 0.4568478393755213 0.6874844866994144 0.7543973819949953 0.7944824998351436 0.9285417099007993 0.8461653199531664 0.7641565111975586 0.734512200808385 1.0 16.17543867090788 -5.519743252449035 1.5004332743690447 0.8356172412090666 0.4579516240313972 0.7716326575781156 0.07653516378217602 0.2128601589018594 0.8985191248893065 0.024084649066941563 0.07804526998408355 3.0217375926088543e-06 5.519743252449035 -0.37766561717766933 APS(ph)LTDLVK ddPTM_PC-9_Lapatinib_30min_R1 2 APSLTDLVK 9 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 APS(0.886)LT(0.114)DLVK;APS(0.999)LT(0.001)DLVK 88.155 0.010336 7443000.0 32496.0 27232.0 31432.0 25420.0 32801.0 32645.0 30456.0 27048.0 31707.0 27314.0 True False 32032.60108096344 27168.945977129104 28847.78229102874 27289.471598634133 30871.70966924721 31248.849449211823 32032.8626576475 28304.74882357862 28135.82377048801 32035.188506382743 0.999919231771688 0.8480969597452476 0.90050296676984 0.8518592482512451 0.9636812239483554 0.9754538963610515 0.9999273970641759 0.8835518110948257 0.8782787017120933 1.0 14.967369859404624 -6.283596200438269 24.823381634903043 0.9480806115249025 0.8964096465097674 0.16301556564352282 0.05519284923860474 1379.2172568271174 1545201.1085196426 0.017520377388047455 0.019884611277695165 5.204797047308358e-07 6.283596200438269 -0.05167096501513513 APS(ph)LTNDEVEEFR ddPTM_PC-9_AZD4547_30min_R2 2 APSLTNDEVEEFR 13 0 Q13206;A0A3B3ISR7;E9PIF2 Q13206 DDX10 Probable ATP-dependent RNA helicase DDX10 1 APS(0.956)LT(0.044)NDEVEEFR;APS(0.839)LT(0.161)NDEVEEFR 158.65 5.1519e-05 19895400.0 9009.9 8524.0 10667.400000000001 14091.400000000001 14318.5 13405.1 12028.2 11565.1 11421.1 10686.4 True False 11874.86078243789 11279.2163040949 10525.943306044664 10842.84543995975 12330.62343030076 12566.876977881884 13098.686498289047 9777.979534559623 12024.796029362225 10312.272388687003 1.1515270674449127 1.0937663280179328 1.0207200614281744 1.0514506435899433 1.1957232087689977 1.2186331493404188 1.2702036956140588 0.9481886402929464 1.166066563811283 1.0 13.3320746562571 -3.6747629857803132 15.618587331501585 1.1152089944992611 45.0203470487136 0.0 0.09986487446471337 0.0 0.0 0.023404568892264638 0.0 0.00021146427815732673 3.6747629857803132 43.90513805421434 APS(ph)LTNDEVEEFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APSLTNDEVEEFR 13 0 Q13206;A0A3B3ISR7;E9PIF2 Q13206 DDX10 Probable ATP-dependent RNA helicase DDX10 1 APS(0.875)LT(0.125)NDEVEEFR 103.66 0.0014425999999999998 9109100.0 7485.8 4192.9 9627.2 10584.0 10336.0 7871.3 7806.4 7255.8 6920.2 7021.5 True False 8752.998088710572 4609.143402089254 9856.74895935932 9991.01279379098 8310.734997596825 7458.5151713682835 7066.921278558302 7065.342938155578 7021.394833267837 8294.442367836578 1.055284695527229 0.5556905693819953 1.1883558318014131 1.2045430362543967 1.0019642827133775 0.8992183971631684 0.8520067974625704 0.8518165085519084 0.8465180083105711 1.0 13.017929277271907 -6.822090918386161 4.780424600255552 0.8759453879671512 0.998229494106627 0.09315528545423224 0.17186067799443 0.5475647675338657 24.954325108273558 0.06497082229386153 0.05811278584357944 1.5062916950463613e-07 6.822090918386161 0.12228410613947582 APS(ph)LTNDEVEEFR ddPTM_PC-9_Lapatinib_30min_R1 2 APSLTNDEVEEFR 13 0 Q13206;A0A3B3ISR7;E9PIF2 Q13206 DDX10 Probable ATP-dependent RNA helicase DDX10 1 APS(0.889)LT(0.111)NDEVEEFR;APS(0.952)LT(0.048)NDEVEEFR 104.26 0.0013594000000000002 16842100.0 6417.4 5629.0 6596.6 7206.4 6289.0 7719.5 4969.0 5412.4 6175.6 6193.200000000001 True False 6325.886699192969 5615.966396344729 6054.253011612374 7736.382695845681 5919.093384649723 7389.354980033413 5226.270506496272 5663.879862937624 5480.038896049004 7263.686368079727 0.8708920482844745 0.773156509210543 0.8334959282132268 1.0650766434304237 0.8148883479690398 1.017300941365797 0.7195066308841638 0.779752810890562 0.7544432149674078 1.0 12.826486195855837 -7.281692301499439 24.856363398921953 0.7950717450667857 0.8914113213259565 0.11058763604428368 0.10918520064445274 1522.6842762693027 1868779.0914362743 0.044832994297375355 0.03026989486161346 5.227664388795446e-08 7.281692301499439 0.09633957625917078 APS(ph)PAPPPLPSSR ddPTM_PC-9_AZD4547_30min_R2 2 APSPAPPPLPSSR 13 0 Q6UXY1;B0QYF0;Q6UXY1-2 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 APS(1)PAPPPLPSSR;APS(1)PAPPPLPSSR 103.13 0.0015743 205952000.0 118157.0 99893.0 143955.0 247020.0 188820.0 173713.0 148654.0 176620.0 131594.0 175327.0 True False 155728.46818172385 132181.45873591644 142046.06264147404 190073.35542095572 162605.6022704465 162850.6986489316 161883.91801904375 149327.43732383798 138549.79018552456 169188.8550953852 0.9204416454850253 0.781265755722475 0.8395710377104414 1.1234389836954466 0.9610893234000125 0.9625379789769234 0.9568237690820529 0.8826080018075082 0.8189061277553598 1.0 17.368275011995266 APS(ph)PAPPPLPSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 APSPAPPPLPSSR 13 0 Q6UXY1;B0QYF0;Q6UXY1-2 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 APS(1)PAPPPLPSSR;APS(1)PAPPPLPSSR;APS(1)PAPPPLPSSR;APS(1)PAPPPLPSSR 143.25 8.5085e-05 302373000.0 364637.0 293863.0 420126.0 406292.0 467341.0 419973.0 429730.0 468873.0 389085.0 312087.0 True False 426362.842190969 323035.77656708995 430143.3971767268 383528.776456437 375768.8858854387 397948.8765597873 389022.8634242235 456565.58056200785 394774.63204849773 368665.9026206678 1.156501968747751 0.876229057992032 1.1667566599434478 1.0403152928711774 1.0192667214794728 1.0794295695125613 1.0552179104681172 1.2384263836620193 1.0708194851822086 1.0 18.49195446424838 -7.576600329922938 24.999711566879725 1.1221382811426124 1.052195282219333 0.03731728572796189 0.09381350563014382 215.44083380829994 100254.16357702762 0.041247417003655494 0.023814209550395732 2.650938607238832e-08 7.576600329922938 -0.06994299892327938 APS(ph)PAPPPLPSSR ddPTM_PC-9_Lapatinib_30min_R1 2 APSPAPPPLPSSR 13 0 Q6UXY1;B0QYF0;Q6UXY1-2 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 APS(1)PAPPPLPSSR;APS(1)PAPPPLPSSR 124.47 0.00015333 269300000.0 244100.0 209308.0 265500.0 248900.0 246200.0 294490.0 209971.0 209960.0 270780.0 192669.0 True False 240619.08923754268 208823.3601858449 243671.61485963783 267204.93630605977 231719.00004782368 281895.3491897196 220842.27098400675 219715.50809666346 240281.9049601899 225971.5799346952 1.0648201393603591 0.9241133785327957 1.0783285886218872 1.182471425757526 1.0254342608693954 1.24748142784675 0.9773010882511385 0.9723147847183272 1.063327985889333 1.0 17.785781813159076 APS(ph)PAPSSVPLGSEKPSNVSQDR ddPTM_PC-9_AZD4547_30min_R2 2 APSPAPSSVPLGSEKPSNVSQDR 23 1 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 APS(0.333)PAPS(0.333)S(0.333)VPLGSEKPSNVSQDR;APS(0.996)PAPS(0.002)S(0.002)VPLGSEKPSNVSQDR 125.03 8.143100000000001e-08 151159000.0 43745.0 38666.4 65107.0 84418.0 68325.0 56188.0 57895.0 68385.0 60996.0 79033.0 True False 57655.00004747505 51164.55763733637 64243.63863984194 64956.734345098586 58839.25312534831 52674.55547763368 63047.54284252379 57817.669580968555 64220.12403419795 76266.07872577295 0.755971737511023 0.6708691267753103 0.8423618955268483 0.851711998707329 0.7714996510691782 0.6906682021378545 0.8266787003593229 0.7581046586761246 0.8420535722717805 1.0 16.218753904031068 -8.691889773550926 2.080006651051704 1.0000407442348038 0.7713345238414797 0.6031736437811945 0.05636948422925142 0.46189828002077576 3.8099052430496507 0.056589450922518665 0.015617929935157667 2.0328729003546424e-09 8.691889773550926 -0.2287062203933241 APS(ph)PAPSSVPLGSEKPSNVSQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APSPAPSSVPLGSEKPSNVSQDR 23 1 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 APS(0.99)PAPS(0.007)S(0.003)VPLGSEKPSNVSQDR;APS(0.792)PAPS(0.104)S(0.104)VPLGSEKPSNVSQDR 97.395 3.7802999999999996e-06 131740000.0 26127.0 24886.0 29869.0 31913.0 33365.0 29216.0 32655.0 24946.1 25625.7 22850.9 True False 30549.78506822802 27356.51761415564 30581.190238813288 30125.018073341984 26827.36776265654 27683.861528171434 29561.68199827338 24291.291307577787 26000.42738343856 26993.58728237513 1.1317423189682843 1.0134450574495328 1.1329057497585955 1.1160064706557713 0.993842258978779 1.025571786312633 1.0951372149627192 0.8998911872464707 0.963207561538698 1.0 14.720329094427248 -7.146787751397998 0.820968973825106 0.9583453681711879 1.090617300587023 0.41905977435844766 0.05701542459643849 0.6290455760376414 0.8517563680742676 0.04468914092816602 0.02940983055456831 7.132015011378122e-08 7.146787751397998 0.13227193241583513 APS(ph)PAPSSVPLGSEKPSNVSQDR ddPTM_PC-9_Lapatinib_30min_R1 1 APSPAPSSVPLGSEKPSNVSQDR 23 1 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 APS(0.966)PAPS(0.024)S(0.01)VPLGSEKPSNVSQDR 48.57899999999999 0.019224 24306000.0 35404.0 26921.0 24658.0 24454.0 21705.0 24093.0 21512.0 18441.0 25449.0 19508.0 True False 34899.132467701544 26858.666078521295 22630.714422632576 26252.42873615262 20428.354573671848 23062.59855352614 22625.786100975605 19297.83618218033 22582.665630149466 22879.93180722394 1.525316279862458 1.1738962469302963 0.9891075993280418 1.1473997806175222 0.8928503260320886 1.007983710259334 0.9888922000122354 0.8434394099062557 0.987007558432468 1.0 14.481795131773861 -1.5228787473399932 0.7579243693962371 0.9575386510378899 107.3388513278341 0.8431830444628592 0.07231646917825864 138.93182699414967 0.5796156023183513 0.02622412718555182 25259.753404567917 0.02999999985772403 1.5228787473399932 106.38131267679621 APS(ph)PEPAAPR ddPTM_PC-9_AZD4547_30min_R2 1 APSPEPAAPR 10 0 P20749 P20749 BCL3 B-cell lymphoma 3 protein 1 APS(1)PEPAAPR 69.65 0.037828 4654300.0 16971.0 13824.0 22863.0 35831.0 34470.0 24911.0 20318.0 31278.0 19535.0 25968.0 True False 22367.424981270997 18292.33765694602 22559.821681581187 27570.716533431576 29684.435495510483 23353.311231994947 22126.262638818524 26444.703796936985 20567.580218507064 25058.86822404405 0.8925951795304703 0.7299746139131086 0.9002729684309916 1.1002378992909745 1.1845880360641423 0.9319379879091021 0.8829713473487328 1.0553031988716561 0.8207705166338046 1.0 14.613033636809737 -5.526753565224266 13.211609605151649 0.9993472379987942 0.8122290455490332 0.33593381790129007 0.10527397891378552 0.36538737748385947 1224.5490916211963 0.029523092446144827 0.05252256345443969 2.973352743624061e-06 5.526753565224266 -0.18711819244976102 APS(ph)PEPAAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APSPEPAAPR 10 0 P20749 P20749 BCL3 B-cell lymphoma 3 protein 1 APS(1)PEPAAPR 70.72800000000001 0.035018 6224500.0 22281.0 35383.0 35022.0 36560.0 38942.0 36543.0 39006.0 26127.0 37385.0 32990.0 True False 26052.73323019054 38895.59040189944 35857.05730167462 34511.66172911924 31311.594647486047 34626.62074972511 35311.06930101521 25441.193933844766 37931.68489952865 38970.825851303685 0.668518889735538 0.9980694417487761 0.9201000111850363 0.8855768635953791 0.8034624353858435 0.8885267374585738 0.9060898384793648 0.652826656302273 0.9733354136312132 1.0 15.25010688429109 APS(ph)PGAYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APSPGAYK 8 0 P54259 P54259 ATN1 Atrophin-1 1 APS(1)PGAYK 77.533 0.023407 20972000.0 136890.0 150770.0 143450.0 146410.0 149140.0 138720.0 149240.0 133600.0 118690.0 115130.0 True False 160062.77329925846 165737.44919578297 146870.39203715467 138207.1223676245 119917.08761044807 131445.27899739673 135102.90679596784 130093.14156090112 120425.61671058065 136002.15763142126 1.1769134849539944 1.21863838105383 1.0799122204751146 1.0162127187877337 0.8817293026735263 0.9664940710251516 0.9933879664035149 0.9565520417217634 0.8854684279123387 1.0 17.053270013996688 -5.618647130675577 1.9300112045175821 0.9489335150739011 1.2002456539286877 0.8501299709772617 0.041122692117725464 0.11861751967462121 0.8836204861060415 0.012318409553544869 0.028991885858571133 2.406317166648917e-06 5.618647130675577 0.25131213885478654 APS(ph)PGAYK ddPTM_PC-9_Lapatinib_30min_R1 1 APSPGAYK 8 0 P54259 P54259 ATN1 Atrophin-1 1 APS(1)PGAYK 77.533 0.023407 27469000.0 224130.0 193710.0 227690.0 193570.0 220990.0 222670.0 189600.0 219490.0 217270.0 191770.0 True False 220933.86509959216 193261.47639650694 208970.20710881735 207805.7835305901 207991.80268305654 213146.92316912216 199416.5602800753 229688.30668763924 192798.76464547045 224917.18898253664 0.9822898200846101 0.8592561434311383 0.9290984297560403 0.9239213084186503 0.9247483646045646 0.9476684469219098 0.8866221438307176 1.021212774918119 0.8571988895897148 1.0 17.779034395722597 -14.522878745280336 0.333840660099637 1.7576886042392965 0.9235407190168486 0.16203676247754362 0.048796528048474126 641.7433049832163 5.497214214435527 345.9113791588258 0.03717704750830622 3.0000000000000132e-15 14.522878745280336 -0.8341478852224479 APS(ph)PGDYK ddPTM_PC-9_AZD4547_30min_R2 1 APSPGDYK 8 0 P55198 P55198 MLLT6 Protein AF-17 1 APS(0.999)PGDY(0.001)K 82.831 0.038826 0.0 104350.0 111010.0 87301.0 72593.0 100740.0 112170.0 106350.0 108410.0 116150.0 105200.0 True False 137531.12938516436 146891.81158113285 86143.33169854002 55857.80540066986 86753.98989897655 105155.99216783243 115814.94397275095 91657.7255139696 122289.45187507525 101516.98002038793 1.354759857489295 1.4469679018390043 0.8485608189018193 0.5502311572847398 0.8545761495422097 1.0358463396637063 1.1408430781677263 0.9028807347850748 1.2046206639570596 1.0 16.631361531328793 -5.258657705132092 24.943580842507345 0.9320376483750373 1.400863924054948 0.5305217627404921 0.172378223019717 187.18933805887272 1678523.8534489244 0.048767208830311964 0.11771601428787486 5.512419938111177e-06 5.258657705132092 0.46882627567991075 APS(ph)PPEAALQPAPTEPR ddPTM_PC-9_AZD4547_30min_R2 2 APSPPEAALQPAPTEPR 17 0 Q9NVR5-2;Q9NVR5 Q9NVR5-2 DNAAF2 Protein kintoun 1 APS(1)PPEAALQPAPTEPR;APS(0.998)PPEAALQPAPT(0.002)EPR 77.74 0.0074842 23734000.0 6356.4 8227.3 69937.0 95842.0 73753.0 67612.0 25568.0 80660.0 40310.0 47967.3 True False 8377.602978666597 10886.613831379627 69009.58968397594 73747.10764413922 63513.66901944846 63384.21095169378 27843.502468220886 68195.8503824075 42440.70430550396 46287.97942710981 0.18098873794780568 0.2351931098768936 1.4908749644742239 1.5932237387952872 1.3721417483660987 1.3693449516738054 0.6015277143835228 1.4732950374253484 0.9168839260382019 1.0 15.498349966717768 -5.251791990915428 24.2676708297087 1.2450503355820937 0.20809062411245108 0.6615728062033727 0.29132196292029167 264.23871555627943 664677.7515995034 0.07606870518204023 0.19551104626825497 5.60025766436798e-06 5.251791990915428 -1.0369597114696425 APS(ph)PPEAALQPAPTEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APSPPEAALQPAPTEPR 17 0 Q9NVR5-2;Q9NVR5 Q9NVR5-2 DNAAF2 Protein kintoun 1 APS(0.999)PPEAALQPAPT(0.001)EPR 71.888 0.012759999999999999 6005600.0 5903.1 6324.4 4904.7 8195.2 9662.0 9273.0 7814.4 7734.7 5581.3 6003.9 True False 6902.378238460469 6952.2446354964995 5021.646649178329 7736.049513196884 7768.800459247342 8786.707555816458 7074.163460643314 7531.67232059207 5662.9159537177775 7092.359543153747 0.9732132439793374 0.9802442463887071 0.7080361082406945 1.0907582259650797 1.0953760045550092 1.2388976478636458 0.9974344105935805 1.061941695815801 0.7984530281158954 1.0 12.792049959361293 -5.829341846791684 24.999999957202963 1.0517600451415845 0.8964514982621122 0.23500195141657065 0.12520255058178148 73.53406960295091 27072.31204111934 0.036094230582258954 0.05353642058656697 1.4813516078644865e-06 5.829341846791684 -0.15530854687947226 APS(ph)PPEAALQPAPTEPR ddPTM_PC-9_Lapatinib_30min_R1 2 APSPPEAALQPAPTEPR 17 0 Q9NVR5-2;Q9NVR5 Q9NVR5-2 DNAAF2 Protein kintoun 1 APS(1)PPEAALQPAPTEPR;APS(0.998)PPEAALQPAPT(0.002)EPR 104.16 0.00080678 15904200.0 12160.0 10901.7 31041.0 15127.8 29251.0 27794.0 17559.4 22450.1 33917.0 16134.8 True False 11986.596170129102 10876.457783448452 28488.9288017251 16240.348876861432 27530.513689678653 26605.3154109785 18468.539813195937 23493.213604119417 30096.91029815631 18923.678681730413 0.6334178661415015 0.5747538819684657 1.5054646234946547 0.8582025276375274 1.4548182809855879 1.4059272437691626 0.9759487108088618 1.2414718089036565 1.5904365532909268 1.0 14.207904949199595 -5.2486270987816015 24.591239292269858 1.251184919932744 0.6040857205478424 0.5557385078990178 0.23243509436343096 437.85055446752835 840383.2152505575 0.05717268606839044 0.14907770471369705 5.641218236840048e-06 5.2486270987816015 -0.6470991993849017 APS(ph)PPLSQVFQTR ddPTM_PC-9_AZD4547_30min_R2 3 APSPPLSQVFQTR 13 0 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 APS(1)PPLSQVFQTR;APS(1)PPLSQVFQTR;APS(0.986)PPLS(0.009)QVFQT(0.005)R 172.09 0.00017173 100673000.0 51582.8 41313.1 62951.5 76116.1 63325.5 67507.9 54143.0 64777.3 43940.5 55875.0 True False 67985.05741110751 54666.75165329693 62116.72197822057 58568.70912702218 54533.84740269656 63286.620341150185 58961.62211111093 54767.45671927 46263.105123691326 53918.83325702639 1.260877754661876 1.0138711902890272 1.1520412855025175 1.0862384363517332 1.0114062955097425 1.1737386830955405 1.0935255559044834 1.0157389062593083 0.8580138391192392 1.0 15.71850165810717 -7.938580860892309 3.2519336551334903 0.9288873524690441 1.1082960081513507 0.48203535165288025 0.07683952560205932 0.2022689588987522 4.242101244703698 0.04876088181711013 0.019614236762122088 1.1519115664974275e-08 7.938580860892309 0.17940865568230657 APS(ph)PPLSQVFQTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APSPPLSQVFQTR 13 0 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 APS(0.994)PPLS(0.006)QVFQTR 119.77 0.00022279 25326000.0 17230.0 17747.0 19692.0 18828.0 20252.0 19096.0 19248.0 16147.0 16618.0 17304.0 True False 20146.698691987913 19508.804874162983 20161.53196232588 17773.128201199594 16283.76598019842 18094.57214341326 17424.69009654772 15723.158359160694 16861.00681183274 20441.078221611366 0.9855986300511184 0.9543921637918916 0.9863242899295823 0.8694809544052781 0.7966197185715174 0.8852063451468398 0.8524349795856384 0.7691941779537519 0.8248589741223342 1.0 14.319183676800776 -5.836415597058533 4.7121256602427355 0.843849940149421 0.9734852291002838 0.4503745990134682 0.05931776862392088 0.16625061789333354 6.819380907276217 0.016177678952761204 0.024986175710569547 1.4574189192228954e-06 5.836415597058533 0.12963528895086274 APS(ph)PPLSQVFQTR ddPTM_PC-9_Lapatinib_30min_R1 4 APSPPLSQVFQTR 13 0 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 APS(0.998)PPLS(0.002)QVFQTR;APS(0.999)PPLS(0.001)QVFQTR;APS(1)PPLSQVFQTR;APS(0.999)PPLS(0.001)QVFQTR 127.07 0.0001216 95781000.0 108921.59999999999 99873.5 96851.1 80418.3 100671.6 98122.6 86209.4 77916.0 102019.6 70529.3 True False 107368.3580102248 99642.24904695942 88888.3764140575 86332.53004958451 94750.29441598085 93926.1251329524 90672.90090616622 81536.26180634265 90529.07833398548 82720.19553061506 1.2979703121045858 1.2045697958980457 1.0745668073422234 1.043669317943434 1.1454312191623557 1.135467880974604 1.0961398280617922 0.985687488808773 1.0944011647129186 1.0 16.33595197538986 -5.046638475306983 2.466656614289995 1.075521838979124 1.3007180834263088 0.6940853810601397 0.04940097786978191 0.19982206469486816 2.1324987948113283 0.013885037023309317 0.0742492198929764 8.981761623817374e-06 5.046638475306983 0.2251962444471849 APS(ph)PPPTASNSSNSQSEK ddPTM_PC-9_AZD4547_30min_R2 1 APSPPPTASNSSNSQSEK 18 0 Q8N108-17;Q8N108;Q8N108-13;Q8N108-12;Q8N108-19;Q8N108-16;Q8N108-14;Q8N108-18;Q8N108-15 Q8N108-17 MIER1 Mesoderm induction early response protein 1 1 APS(0.972)PPPT(0.026)AS(0.001)NS(0.001)SNSQSEK 111.11 0.0021397 0.0 8278.9 10574.0 10225.0 9631.6 10804.0 9366.1 11263.0 11726.0 11351.0 9157.9 True False 10911.417988182455 13991.838714159961 10089.40981910368 7411.183426736615 9304.051090614894 8780.436286379028 12265.385180677868 9914.016136673798 11950.99068647422 8837.284708447822 1.2347025526689106 1.5832735026387403 1.141686632485532 0.8386267582453291 1.0528178504559071 0.9935672071293064 1.3879133223978881 1.1218396219821567 1.3523374068790515 1.0 13.109387448463838 -5.378966024419064 7.248186591080613 1.1074271340382196 1.4070319166435168 0.32268807165059554 0.1731018285441196 0.28436247769116313 15.737816942373765 0.04657146319667244 0.0976269357548185 4.178630554910234e-06 5.378966024419064 0.2996047826052972 APS(ph)PPSRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APSPPSRR 8 1 Q7Z2K8 Q7Z2K8 GPRIN1 G protein-regulated inducer of neurite outgrowth 1 1 APS(0.625)PPS(0.375)RR 55.721000000000004 0.040494 6158900.0 2335.2 2836.7 2729.3 4511.1 5529.0 3117.1 2801.5 1912.6 2766.3 2850.4 True False 2730.503237697631 3118.30882890281 2794.3768629278893 4258.35769218353 4445.632140258599 2953.6337886590613 2536.121638896428 1862.396276567208 2806.7519041745636 3367.154956246016 0.8109229522189328 0.9260960274840929 0.8298925648623231 1.264675296360908 1.3202933034050084 0.8771897423907148 0.7531942164384104 0.5531067921636615 0.8335677866467315 1.0 11.717314400084735 -6.995350734951482 24.94159664744519 0.7573640472957537 1.0336893805586258 0.2776662896347333 0.18564705341015258 162.29584128678502 870649.9958504438 0.07057421259776209 0.06201153693866651 1.0107628354495451e-07 6.995350734951482 0.2763253332628721 APS(ph)PPVEHPR ddPTM_PC-9_AZD4547_30min_R2 5 APSPPVEHPR 10 0 Q86WR7;Q86WR7-2 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 APS(1)PPVEHPR;APS(1)PPVEHPR;APS(1)PPVEHPR;APS(1)PPVEHPR;APS(1)PPVEHPR 124.38 0.00023506 538791400.0 58025.9 41234.3 84885.7 171246.0 107535.6 97384.5 53986.1 121196.7 80304.3 104647.3 True False 76476.92918630196 54562.48109431494 83760.06015466899 131767.880424326 92606.13813957114 91295.03182016843 58790.75831506645 102468.53483810445 84549.02135352221 100983.62987915904 0.7573200654186946 0.5403101587812454 0.8294419625725432 1.3048439690869162 0.9170410912183219 0.9040577361837323 0.5821810761349911 1.0147044125936284 0.8372547258867292 1.0 16.62376191586639 -5.513877887778216 24.830068248414833 0.9320199563735327 0.6578302866721701 0.2989134816174781 0.17508252049172732 482.3499856622746 1330624.5119207732 0.04881629462727728 0.09069224957136232 3.0628244985770635e-06 5.513877887778216 -0.2741896697013626 APS(ph)PPVEHPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 APSPPVEHPR 10 0 Q86WR7;Q86WR7-2 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 APS(1)PPVEHPR;APS(1)PPVEHPR;APS(1)PPVEHPR;APS(1)PPVEHPR;APS(1)PPVEHPR;APS(1)PPVEHPR;APS(1)PPVEHPR;APS(1)PPVEHPR 126.12 0.00020221 530330300.0 108929.3 115413.8 150675.1 195644.1 227059.7 176199.30000000002 213943.5 237111.40000000002 147228.6 101252.5 True False 127368.87903825639 126871.319320768 154267.76582249865 184682.79536373023 182568.98174669483 166959.09852685974 193677.2228631943 230887.47699029525 149381.53974585346 119608.77673565128 1.064879037428464 1.0607191443916173 1.2897696141767891 1.5440572205825647 1.5263844905812607 1.395876649552716 1.6192559455000743 1.9303556418822199 1.2489178789613684 1.0 16.86796373093288 -5.495770679569315 2.6185982701987447 1.5115198428068213 1.0588554340885685 0.31296559729680185 0.23123405350694493 0.28874662194874046 3.9064397859160342 0.06309176904354434 0.14708719297531314 3.193223527216119e-06 5.495770679569315 -0.45266440871825275 APS(ph)PPVEHPR ddPTM_PC-9_Lapatinib_30min_R1 7 APSPPVEHPR 10 0 Q86WR7;Q86WR7-2 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 APS(1)PPVEHPR;APS(1)PPVEHPR;APS(1)PPVEHPR;APS(1)PPVEHPR;APS(1)PPVEHPR;APS(1)PPVEHPR;APS(1)PPVEHPR 120.57 0.00039368 478464600.0 25530.5 31584.2 65499.7 46217.3 55498.9 43865.7 33586.82 35103.16 67271.8 44324.0 True False 25166.4303882797 31511.06872542746 60114.56750215372 49616.27441839316 52234.56381703559 41989.66626694108 35325.78119802761 36734.18096398595 59694.94148054115 51985.344341982476 0.48410625546161323 0.6061529287588013 1.1563752873635622 0.9544281190482353 1.0047940333608956 0.8077212298665288 0.6795334655405776 0.7066257120917068 1.1483032811678913 1.0 15.66581733693278 -5.077159212015024 6.577339586130524 0.9112113720937965 0.5124261008016475 0.5005377619081279 0.15559677237538844 0.18628092798680768 13.038848778794096 0.04203618085079309 0.1156425145326259 8.372223008246659e-06 5.077159212015024 -0.398785271292149 APS(ph)PSGLMSPSR ddPTM_PC-9_AZD4547_30min_R2 2 APSPSGLMSPSR 12 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 APS(0.846)PS(0.152)GLMS(0.002)PSR;APS(0.858)PS(0.141)GLMS(0.002)PSR 74.392 0.018391 60456100.0 60439.0 60629.0 89902.0 118367.0 103662.0 79476.0 90784.0 121589.0 73459.0 88631.0 True False 79657.34479070398 80226.13858528511 88709.84073907677 91079.31690191996 89270.32063636812 74506.35315619734 98863.60012808832 102800.21388726168 77341.89277047919 85528.05566717681 0.9313592384314444 0.9380096152013143 1.037201653271314 1.064905734047612 1.0437548233734428 0.8711334845039709 1.1559201171695677 1.2019472801684818 0.9042868117035983 1.0 16.384110122735926 -5.261470441162696 5.250276394714223 1.042304052940482 0.9330914356560943 0.14965006439442297 0.09436611320154324 0.2965556712819568 28.45383377585374 0.025144662042834207 0.06150337588596086 5.476833759758995e-06 5.261470441162696 -0.10921261728438758 APS(ph)PSGLMSPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 APSPSGLMSPSR 12 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 APS(0.814)PS(0.184)GLMS(0.001)PSR;APS(0.972)PS(0.027)GLMSPSR;APS(0.833)PS(0.167)GLMSPSR;APS(0.811)PS(0.184)GLMS(0.004)PS(0.001)R 88.803 0.006901000000000001 62598800.0 170904.0 177561.0 227795.0 227912.0 254418.0 197059.0 214492.0 172963.0 174834.0 172451.0 True False 199834.67169213574 195188.0826202317 233226.49671734875 215142.82954067385 204566.61925489473 186724.87913745662 194173.76497239814 168422.9045194472 177390.6164965674 203715.00117863473 0.9809521661927273 0.9581429030308578 1.1448665801142244 1.0560971371569157 1.004180438707669 0.9165985718141605 0.9531638016295618 0.8267574972142557 0.8707783691443329 1.0 17.63619269592452 -6.735659121541306 2.435758126919235 0.9006099752831914 1.0375111112013038 0.4525091504572172 0.06356697994941662 0.26144964927755526 3.180163676609667 0.025138075430826405 0.023621023254946 1.837980411204815e-07 6.735659121541306 0.13690113591811237 APS(ph)PSGLMSPSR ddPTM_PC-9_Lapatinib_30min_R1 2 APSPSGLMSPSR 12 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 APS(0.821)PS(0.178)GLMS(0.001)PSR;APS(0.769)PS(0.23)GLMSPSR 81.565 0.011504 43134500.0 128919.0 110311.0 179079.0 122426.0 115352.0 90892.0 91589.0 92715.0 102105.0 76669.0 True False 127080.59141915102 110055.5816569874 164355.81588493066 131429.61644116382 108567.2221507576 87004.76103960062 96331.03027158113 97022.87737274815 90604.85968668367 89921.13449497904 1.4132449744197442 1.2239122901983919 1.8277773830145334 1.4616098560066821 1.2073604582560034 0.9675674303737654 1.0712835287566351 1.0789774608344789 1.0076036094911904 1.0 16.456372617065085 -6.417469720646479 3.058941105240151 1.0349440771446146 1.4885429528089231 0.6946063381323313 0.14241994947831418 0.15834475840142961 2.8356225645886344 0.04915540750300334 0.055720891640562306 3.8241091471901713e-07 6.417469720646479 0.45359887566430857 APS(ph)PSINR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APSPSINR 8 0 E9PFK9;Q9UJ41;Q9UJ41-4;Q9UJ41-3 E9PFK9 RABGEF1 Rab5 GDP/GTP exchange factor 1 APS(0.792)PS(0.208)INR 79.986 0.019938 12539000.0 65385.0 73989.0 88359.0 91918.0 111250.0 84358.0 84243.0 74322.0 83596.0 49400.0 True False 76453.3890873843 81334.13894373397 90465.81366337332 86768.13246217696 89451.36111480708 79934.11797622821 76262.89317349698 72371.12625066823 84818.43335190586 58355.82894981519 1.310124292007447 1.3937620355574016 1.5502446849169438 1.4868803001118494 1.5328607737152256 1.369770928024515 1.3068599066441415 1.2401696206373127 1.453469771200542 1.0 15.8325891481982 -7.159924878776441 2.4613382521371414 1.264190079207464 1.45798770238743 0.38031382885727316 0.1222623912888193 0.34887412195092493 4.127997210376942 0.05376936445016376 0.03842735072725271 6.919506493543365e-08 7.159924878776441 0.19379762317996585 APS(ph)PSSR ddPTM_PC-9_AZD4547_30min_R2 2 APSPSSR 7 0 Q9UQ35;I3L3Q8 Q9UQ35;REV__O95996-2 SRRM2 Serine/arginine repetitive matrix protein 2 1 APS(0.847)PS(0.152)S(0.001)R;APS(0.912)PS(0.088)SR 90.601 0.015819 12535900.0 10401.3 11509.8 12118.2 15341.8 11878.7 14318.6 11739.400000000001 13435.1 14228.7 16299.5 True False 13708.69703952 15230.11776359355 11957.504750108774 11804.985038447168 10229.547546287224 13423.255678473075 12784.18385776879 11359.014002884716 14980.80003353323 15728.859466181684 0.8715633240283445 0.968291298955244 0.7602270702347091 0.7505302634198517 0.6503680427866735 0.8534157042558717 0.8127851790688203 0.7221765842149911 0.952440325742827 1.0 13.941126441139698 -8.41199385353858 5.166993324299832 0.9979544688528914 0.7992277486205466 0.42594164649230803 0.0831677509701987 0.21684757906884633 7.801837059943523 0.08622262843801719 0.02243817344418787 3.872631257212067e-09 8.41199385353858 -0.19872672023234483 APS(ph)PSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APSPSSR 7 0 Q9UQ35;I3L3Q8 Q9UQ35;REV__O95996-2 SRRM2 Serine/arginine repetitive matrix protein 2 1 APS(0.979)PS(0.021)SR;APS(0.665)PS(0.332)S(0.004)R 99.13600000000001 0.011939 25807000.0 4708.9 9420.9 13512.5 6061.7 25528.7 28026.2 9862.6 13133.8 27574.2 21591.6 True False 5506.0237649856 10356.14469144092 13834.68924644162 5722.082601296553 20526.53449430631 26556.456734694635 8928.343128959463 12789.05166641138 27977.42050973872 25505.986160988446 0.2158718243722368 0.406028005585634 0.5424095017977332 0.22434273135647315 0.804773215383523 1.041185256162057 0.35004892861642867 0.5014137303176424 1.096896247537778 1.0 14.638548261584562 -5.990743291656643 0.2356574640769787 1.018572327924389 6.56280947092375e-21 0.4360968917285942 0.24239543650786483 6.899928743436799 0.5697208478092927 0.48386234399012207 2.0740160202047075 1.0215431320790225e-06 5.990743291656643 -1.018572327924389 APS(ph)PSSR ddPTM_PC-9_Lapatinib_30min_R1 1 APSPSSR 7 0 Q9UQ35;I3L3Q8 Q9UQ35;REV__O95996-2 SRRM2 Serine/arginine repetitive matrix protein 2 1 APS(0.855)PS(0.145)SR 88.177 0.017446 10105000.0 1880.9 3524.3 3461.2 2938.4 3220.1 3402.9 4665.9 3881.8 3854.6 1053.3 True False 1854.078021085184 3516.139699882345 3176.6334966183736 3154.499738215052 3030.700048960181 3257.365899547342 4907.477471575962 4062.1625992076097 3420.454357262533 1235.3615015659718 1.5008384337175096 2.846243545249879 2.571420181535204 2.5535033544564385 2.4532900249185343 2.6367714190690195 3.972503162317374 3.2882379724949513 2.768788207279156 1.0 10.270717561452543 -7.011047817855227 24.36081870363585 2.9990071456195038 2.4418556272661758 0.010457778006996987 0.7847805536890125 917.7981239140523 2023776.74698265 0.2749339636489139 0.22666866535893265 9.748822927044171e-08 7.011047817855227 -0.557151518353328 APS(ph)PT(ph)GPALISGASPVHCAADGTVELK ddPTM_PC-9_Lapatinib_30min_R1 1 APSPTGPALISGASPVHCAADGTVELK 27 0 E7EWD6;Q76L83 E7EWD6 ASXL2 Putative Polycomb group protein ASXL2 2 APS(0.993)PT(0.814)GPALIS(0.101)GAS(0.092)PVHCAADGTVELK 71.472 0.00085833 3442200.0 10505.0 11193.0 12520.0 12232.0 14824.0 12487.0 9166.2 7878.3 12857.0 9665.3 True False 10355.196773618934 11167.083296195871 11490.653928597598 13131.58208475582 13952.08146510535 11952.960118618716 9640.780985438942 8244.354579148163 11408.909269787882 11335.934226797292 0.9134841969301508 0.9851048067831701 1.0136486061673293 1.1584031648413902 1.2307835583699562 1.054430969647197 0.8504619727458249 0.7272761480618979 1.006437497036467 1.0 13.468615672156846 -7.247627584206297 11.495743086526836 0.8733079364834704 1.0661893236135442 0.33196082011692074 0.11135899379201494 0.7740687712640235 640.6385095335766 0.046069019727996346 0.03478572247261663 5.6542162680252414e-08 7.247627584206297 0.19288138713007386 APS(ph)PTAEQPPGGGDSAR ddPTM_PC-9_AZD4547_30min_R2 4 APSPTAEQPPGGGDSAR 17 0 Q15742-2;Q15742-3;Q15742 Q15742-2 NAB2 NGFI-A-binding protein 2 1 APS(0.991)PT(0.009)AEQPPGGGDSAR;APS(0.978)PT(0.022)AEQPPGGGDSAR;APS(0.96)PT(0.04)AEQPPGGGDSAR;APS(0.997)PT(0.003)AEQPPGGGDSAR 175.19 5.651900000000001e-06 48976700.0 9447.5 16147.4 31764.700000000004 43033.1 29372.5 24288.800000000003 18019.7 42102.0 16453.6 27400.5 True False 12451.608479792452 21366.73127038269 31343.479323313728 33112.48364976736 25294.635381255644 22770.017496354172 19623.418391215582 35596.10330771281 17323.303705309852 26441.21683506311 0.4709166207237728 0.8080842649438411 1.1854023027317653 1.2523055900308502 0.9566365851859355 0.8611561880223061 0.7421526215538388 1.3462354448267906 0.655162877464013 1.0 14.690500951308655 -4.883216704417994 3.3701510924543294 1.0056476359302586 0.4538431039652796 0.3790674461237148 0.2068547817373782 0.2763838287752591 5.352761243791459 0.052345338652576325 0.3401951123500968 1.3085288298828144e-05 4.883216704417994 -0.551804531964979 APS(ph)PTAEQPPGGGDSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 APSPTAEQPPGGGDSAR 17 0 Q15742-2;Q15742-3;Q15742 Q15742-2 NAB2 NGFI-A-binding protein 2 1 APS(0.891)PT(0.109)AEQPPGGGDSAR;APS(0.959)PT(0.041)AEQPPGGGDSAR;APS(0.941)PT(0.059)AEQPPGGGDSAR;APS(0.989)PT(0.011)AEQPPGGGDSAR 168.55 1.8553e-05 43268300.0 12546.9 9708.1 48252.9 14946.7 32340.8 27404.899999999998 21178.199999999997 21691.3 23379.7 14818.8 True False 14670.842357429097 10671.856009402245 49403.432136142284 14109.284856855216 26003.852400375323 25967.738800430754 19172.04757910988 21121.926358832105 23721.583882453106 17505.33113444374 0.8380785398890592 0.6096346265855063 2.8221935224598744 0.8059993123519719 1.4854818912399648 1.4834188854237815 1.0952119346880955 1.2065996465083886 1.3551062645012284 1.0 14.09550673189007 -7.270123244773591 23.158044068727854 1.1814461349412935 1.3571695301971063 0.02085531320006495 0.5815410906387584 1405.5869854201014 3748371.0577549394 0.24172206107268762 0.16619213435175198 5.368794182614687e-08 7.270123244773591 0.17572339525581282 APS(ph)PTAEQPPGGGDSAR ddPTM_PC-9_Lapatinib_30min_R1 3 APSPTAEQPPGGGDSAR 17 0 Q15742-2;Q15742-3;Q15742 Q15742-2 NAB2 NGFI-A-binding protein 2 1 APS(0.965)PT(0.035)AEQPPGGGDSAR;APS(0.962)PT(0.038)AEQPPGGGDSAR;APS(0.989)PT(0.011)AEQPPGGGDSAR 118.23 0.00011536 34938100.0 10776.4 12753.199999999999 24840.9 13868.2 20977.199999999997 18853.3 17437.4 15520.5 22334.0 12218.8 True False 10622.726559850273 12723.670748954273 22798.577090646977 14888.113690959017 19743.362338761985 18046.988308188855 18340.223250146526 16241.639090370893 19818.509732553674 14330.803299472413 0.741251298888552 0.8878546780013856 1.5908792141112078 1.038888984786158 1.3776870651409217 1.259314494174465 1.2797763577441412 1.1333376609089894 1.3829308321664906 1.0 13.806831860306774 -5.069100666743359 7.478621723850716 1.2596792426265044 0.7761749642102278 0.542814437212489 0.16513967075354033 0.15886309577798916 15.266003467617145 0.03825910021892466 0.10378309571805151 8.529023936653885e-06 5.069100666743359 -0.48350427841627663 APS(ph)PTAEQPPGGGDSARR ddPTM_PC-9_AZD4547_30min_R2 1 APSPTAEQPPGGGDSARR 18 1 Q15742-2;Q15742-3;Q15742 Q15742-2 NAB2 NGFI-A-binding protein 2 1 APS(0.593)PT(0.407)AEQPPGGGDSARR 63.125 0.0086614 3731600.0 4107.8 5080.8 10707.0 23046.0 21214.0 11307.0 5865.5 16723.0 9107.2 12595.0 True False 5413.994952452122 6723.0692395407505 10565.018184170483 17733.10075715064 18268.80228029475 10599.97150255577 6387.518137020866 14138.844606310422 9588.587999282709 12154.052883619637 0.44544770409455076 0.5531545159394216 0.8692588624827574 1.4590277767385762 1.503103734632925 0.8721347195092144 0.5255463505206157 1.1633028703837338 0.788921036554442 1.0 13.569149853883369 -5.325167249821407 3.4782900870477906 1.0474997361111769 0.48396982643364317 0.3725253483492491 0.27821052114123185 0.2665591782527082 6.348137830136378 0.0824126814461593 0.20443701140764556 4.729690802067494e-06 5.325167249821407 -0.5635299096775337 APS(ph)PTAEQPPGGGDSARR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APSPTAEQPPGGGDSARR 18 1 Q15742-2;Q15742-3;Q15742 Q15742-2 NAB2 NGFI-A-binding protein 2 1 APS(0.554)PT(0.445)AEQPPGGGDS(0.001)ARR;APS(0.739)PT(0.261)AEQPPGGGDS(0.001)ARR 55.815 0.017735 6766600.0 12478.6 9630.4 13221.9 16048.699999999999 22315.0 21149.5 17136.7 24386.0 19185.3 12942.599999999999 True False 14590.980516415588 10586.442466903663 13537.160240334986 15149.543369587413 17942.53593956785 20040.3829884331 15513.387717036027 23745.893339102764 19465.84871747832 15288.990926434777 0.9543455540409587 0.692422575030745 0.8854188157656067 0.9908792177640541 1.1735591986352136 1.310772116018666 1.0146770177103883 1.5531367278167416 1.2731938171159305 1.0 13.900205571502038 -6.10705224915877 1.651500377396829 1.2550604226477495 0.8182256641212887 0.5370462320454905 0.15890582359926192 0.2660487082670844 1.447480593128737 0.053951230300852505 0.08250505656006643 7.815337740620261e-07 6.10705224915877 -0.4368347585264608 APS(ph)PTAEQPPGGGDSARR ddPTM_PC-9_Lapatinib_30min_R1 2 APSPTAEQPPGGGDSARR 18 1 Q15742-2;Q15742-3;Q15742 Q15742-2 NAB2 NGFI-A-binding protein 2 1 APS(0.777)PT(0.223)AEQPPGGGDSARR;APS(0.485)PT(0.485)AEQPPGGGDS(0.029)ARR 78.708 0.0019979 7657700.0 30130.0 15457.599999999999 19020.5 13911.0 11938.0 11445.5 9198.2 8548.5 19454.3 9967.3 True False 29700.340674834715 15421.808876912117 17456.707911253245 14934.061345735618 11235.830311011037 10956.002645763632 9674.43778886174 8945.694517833543 17263.151871139016 11690.134524407584 2.5406329253802857 1.319215689495553 1.493285460043745 1.2774926853540571 0.9611378113358735 0.9372007330530565 0.8275728366224261 0.765234523106301 1.4767282476600803 1.0 13.5130039113505 -1.6002183295937051 0.7304640638574174 0.9943542034531466 199.99999999634812 0.7849169996493568 0.2289978995395209 131.5347560608505 0.6999647650698302 0.0871535633363826 42836.12508270099 0.025106239671250297 1.6002183295937051 199.00564579289497 up APS(ph)PTGPALIS(ph)GASPVHCAADGTVELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APSPTGPALISGASPVHCAADGTVELK 27 0 E7EWD6;Q76L83 E7EWD6 ASXL2 Putative Polycomb group protein ASXL2 2 APS(0.903)PT(0.275)GPALIS(0.461)GAS(0.268)PVHCAADGT(0.093)VELK 49.312 0.041089 0.0 10174.0 10620.0 13458.0 14023.0 13718.0 11414.0 12733.0 9642.5 11029.0 8492.6 True False 11896.257254340404 11674.283414865105 13778.88975974921 13237.336773179408 11030.056375486958 10815.429746801372 11526.83806106309 9389.394592073255 11190.278260181918 10032.241152615394 1.1858025612989838 1.163676514277334 1.3734607801126342 1.3194795232497425 1.0994608490458222 1.0780671618905215 1.1489793642029884 0.9359219390001855 1.1154315461470565 1.0 13.292356312377478 -6.386577379182836 4.703788601361406 1.0605459818294998 1.2609831032099452 0.6051694452190173 0.07866883345627262 0.16954232942796169 5.764989559130664 0.026050360265816697 0.02959414947360429 4.1060347525188964e-07 6.386577379182836 0.20043712138044545 APS(ph)PTGPALISGASPVHCAADGTVELK ddPTM_PC-9_AZD4547_30min_R2 1 APSPTGPALISGASPVHCAADGTVELK 27 0 E7EWD6;Q76L83 E7EWD6 ASXL2 Putative Polycomb group protein ASXL2 1 APS(0.712)PT(0.139)GPALIS(0.139)GAS(0.01)PVHCAADGTVELK 66.282 0.00020356 4516900.0 7582.2 7863.3 14050.0 24216.0 20183.0 15186.0 9796.0 19198.0 12969.0 15784.0 True False 9993.181880442688 10404.957949787591 13863.687819893075 18633.375333470445 17380.93883393933 14236.417019351908 10667.825022633446 16231.390226152453 13654.514863261755 15231.406964275691 0.6560905308275898 0.6831252013810521 0.9102040180798454 1.2233522075257957 1.1411249712324825 0.9346751125974462 0.7003834279823368 1.0656527177182094 0.8964710151391504 1.0 13.894761592985324 -5.318879598369857 3.874902905933496 0.9928631666749465 0.6637065174803185 0.4745003301555458 0.13432933932459087 0.20083648887865554 6.116522502378258 0.03916303970928574 0.093706331505161 4.798664659763965e-06 5.318879598369857 -0.32915664919462795 APS(ph)PTKPLR ddPTM_PC-9_Lapatinib_30min_R1 1 APSPTKPLR 9 1 Q96FF9;B5MBX0 Q96FF9 CDCA5 Sororin 1 APS(0.998)PT(0.002)KPLR 56.434 0.040935 32622000.0 35024.0 54028.0 58901.0 44152.0 54259.0 53816.0 48307.0 51953.0 51798.0 48421.0 True False 34524.551337385026 53902.901485470444 54058.38714443513 47399.08536675433 51067.59229729839 51514.41513122329 50808.10009203367 54366.9260437511 45963.9637828788 56790.5053330731 0.6079282291097866 0.9491534045934787 0.9518912858300124 0.8346304560729187 0.8992276437370974 0.9070955581235659 0.8946583551959439 0.9573242168720308 0.8093600068057637 1.0 15.793362128753234 -4.7566389111839555 24.99774219620581 0.907964080175615 0.6079277729103417 0.7348177204298043 0.0546698450228685 72.58802445205455 377947.09671364893 0.012836646960598544 0.10222805874711702 1.7513021821669424e-05 4.7566389111839555 -0.3000363072652733 APS(ph)PTSSAGEEGTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APSPTSSAGEEGTK 14 0 O94964-2;H0YDM2;O94964-3;O94964 O94964-2 SOGA1 Protein SOGA1;N-terminal form;C-terminal 80 kDa form 1 APS(0.969)PT(0.029)S(0.001)SAGEEGTK;APS(0.805)PT(0.108)S(0.076)S(0.011)AGEEGTK 128.73 0.0005035 0.0 18817.2 24162.0 19514.6 17499.9 21075.7 15600.1 17245.5 15967.0 15576.300000000001 8904.7 True False 22002.58030335897 26560.643678904944 19979.90207353262 16519.43733844131 16946.067878178354 14782.003293593476 15611.881393392248 15547.883168434922 15804.073920035522 10519.051620433589 2.091688594874681 2.5250036445595585 1.8994014664516932 1.5704302949090754 1.6109881850242167 1.405260077332349 1.4841529404671499 1.4780689105311233 1.502423839173449 1.0 13.360717019144134 -1.522878745332609 0.21313182453409119 1.1128102862642308 7.764634227588143 0.7776195842283427 0.18813085942119992 23.428325715608988 0.29418439944458297 0.3182313920531378 53.06604047909502 0.029999999996389224 1.522878745332609 6.651823941323912 up APS(ph)RNLAPTPR ddPTM_PC-9_AZD4547_30min_R2 2 APSRNLAPTPR 11 1 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 APS(0.893)RNLAPT(0.107)PR;APS(0.999)RNLAPT(0.001)PR 71.529 0.013919999999999998 10319900.0 16667.199999999997 10598.5 20004.1 51833.0 39736.0 20309.4 17138.800000000003 17468.2 13528.3 28802.0 True False 21967.022900703534 14024.25786003634 19738.832563553246 39883.702661867064 34219.342293287045 19039.450007429572 18664.119997745012 14768.891069302865 14243.378319428173 27793.65074664651 0.7903611907965709 0.5045849495582534 0.7101921494042976 1.4349933020828256 1.2311927859068978 0.6850287564229687 0.6715245927164486 0.5313764357165217 0.5124687810631259 1.0 14.76246772715586 -6.968273452506884 24.839624057929385 0.6452883187913074 0.9289984128327888 0.17269546279897552 0.27417169450775103 338.07129390292886 264684.6991211976 0.10773129060479283 0.09500927923568889 1.0757876331614155e-07 6.968273452506884 0.2837100940414814 APS(ph)RQDVYGPQPQVR ddPTM_PC-9_AZD4547_30min_R2 7 APSRQDVYGPQPQVR 15 1 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 APS(1)RQDVYGPQPQVR;APS(1)RQDVYGPQPQVR;APS(1)RQDVYGPQPQVR;APS(1)RQDVYGPQPQVR;APS(1)RQDVYGPQPQVR;APS(1)RQDVYGPQPQVR;APS(1)RQDVYGPQPQVR 186.42 1.8011000000000002e-06 754181400.0 106529.49999999999 96463.90000000001 136205.7 238573.0 256827.0 217189.0 155055.80000000002 222423.0 158167.30000000002 184546.0 True False 140403.6650487484 127643.96922062174 134399.52342277652 183573.68076610685 221171.00420671486 203608.1374961159 168855.4658171135 188052.63612207063 166527.70057305714 178085.10071143036 0.7884077022044585 0.7167582729307401 0.7546926884161854 1.030819984562157 1.2419399675950489 1.1433193270112088 0.9481728967923454 1.0559706307311565 0.935101813165713 1.0 17.442207294476063 -5.776973020378758 5.370199805341496 1.0624162197248943 0.7471837033071553 0.7127568838386467 0.08648926123699781 0.09325171549917607 7.8358840324482575 0.026182620926116118 0.04177187147000434 1.6711944304865047e-06 5.776973020378758 -0.315232516417739 APS(ph)RQDVYGPQPQVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 APSRQDVYGPQPQVR 15 1 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 APS(1)RQDVYGPQPQVR;APS(0.991)RQDVY(0.009)GPQPQVR;APS(1)RQDVYGPQPQVR;APS(1)RQDVYGPQPQVR;APS(1)RQDVYGPQPQVR;APS(0.997)RQDVY(0.003)GPQPQVR;APS(1)RQDVYGPQPQVR 106.42 0.0045578 481562100.0 52564.299999999996 51274.2 101231.2 97341.8 132330.0 96948.3 101193.6 86648.2 87630.7 82992.5 True False 61462.39779775166 56364.363716617365 103644.93572946388 91888.05453237343 106400.88643885331 91864.16048027184 91607.8096297802 84373.7765613569 88912.13320650316 98038.38328173144 0.6269217804329564 0.574921391294713 1.057187320517322 0.9372661141128378 1.085298256429736 0.9370223927120785 0.9344075918360282 0.8606198280411586 0.9069114588619611 1.0 16.581059072947795 -5.254590906016137 24.999339457745386 0.9610983255149365 0.6009215399305353 0.8331394317281056 0.06512777062734651 205.84937848031345 751417.9738158943 0.0175587607365558 0.04432657323609443 5.5642815117380806e-06 5.254590906016137 -0.36017678558440114 APS(ph)RQDVYGPQPQVR ddPTM_PC-9_Lapatinib_30min_R1 5 APSRQDVYGPQPQVR 15 1 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 APS(1)RQDVYGPQPQVR;APS(1)RQDVYGPQPQVR;APS(1)RQDVYGPQPQVR;APS(1)RQDVYGPQPQVR;APS(1)RQDVYGPQPQVR 186.77 1.7057e-06 651880800.0 379819.0 378659.4 405331.1 365627.5 516714.4 370876.9 255905.9 234195.0 525901.0 190681.8 True False 374402.7114097252 377782.6374240642 372006.3415812928 392516.96604758454 486322.2748915972 355015.3595432802 269155.455344815 245076.55467088064 466668.4913969606 223640.89506247296 1.674124543747411 1.6892377278249247 1.6634092860224634 1.755121602146767 2.174567736172517 1.5874348895094006 1.2035162677632272 1.0958485683149306 2.0866867451348696 1.0 17.77082449852667 -7.002248529770662 24.98932145442213 1.3603538529714845 1.7869577060120867 0.3180655804865723 0.3067205968061498 111.25054784967638 1236410.7197374357 0.10746922243629682 0.09327282260705108 9.948359486645299e-08 7.002248529770662 0.4266038530406022 APS(ph)SSSLNSATSSQSK ddPTM_PC-9_AZD4547_30min_R2 1 APSSSSLNSATSSQSK 16 0 Q5F1R6;Q5F1R6-3;Q5F1R6-2;A0A2R8Y534;A0A2R8Y4Q0 Q5F1R6 DNAJC21 DnaJ homolog subfamily C member 21 1 APS(0.416)S(0.168)S(0.416)SLNSATSSQSK 201.04 2.1491e-12 14984000.0 6588.9 6661.1 10334.0 9623.6 11465.0 9197.3 13474.0 16011.0 12402.0 9914.7 True False 8684.033142366176 8814.170310089929 10196.964407884356 7405.027703137853 9873.282650305428 8622.19137706343 14673.159897403324 13536.867846178082 13057.54440081519 9567.589370799815 0.9076511131288468 0.921252989492911 1.0657819867359053 0.7739700583030791 1.0319509196787422 0.9011874405248065 1.5336318615622926 1.414867143806617 1.364768479787258 1.0 13.22393975682526 -7.249893948772857 24.779654007626014 1.3628891332017454 0.9362881370780957 0.6285457508700178 0.14767947371884638 373.73069229069523 802129.5368825007 0.05347685312031595 0.04105094251843314 5.624786611965032e-08 7.249893948772857 -0.42660099612364977 APS(ph)SSSLNSATSSQSK ddPTM_PC-9_Lapatinib_30min_R1 1 APSSSSLNSATSSQSK 16 0 Q5F1R6;Q5F1R6-3;Q5F1R6-2;A0A2R8Y534;A0A2R8Y4Q0 Q5F1R6 DNAJC21 DnaJ homolog subfamily C member 21 1 APS(0.499)S(0.499)S(0.002)SLNSATSSQSK 207.21 3.430799999999999e-63 0.0 11689.0 13741.0 12267.0 10254.0 13518.0 14771.0 11901.0 11456.0 13111.0 14982.0 True False 11522.31271649993 13709.18355874452 11258.454611989366 11008.113366341255 12722.897817410556 14139.278762882763 12517.175547959778 11988.28758218414 11634.301115049313 17571.61873773985 0.6557342774432395 0.7801889947282037 0.6407181250642981 0.6264712164906199 0.7240595193477911 0.8046656926669369 0.712351874621302 0.6822528852413591 0.662107531963545 1.0 14.100959481387362 -11.048346102525237 2.87851914971172 1.0128538731713996 0.7010693714104069 0.7261871597598515 0.055481951512667736 49909687.61666835 53757084.65256699 5013545.850178105 0.01444429241058708 8.946515062924235e-12 11.048346102525237 -0.3117845017609927 APS(ph)TPR ddPTM_PC-9_Lapatinib_30min_R1 1 APSTPR 6 0 Q86VL0;Q5JRI7;A0A0A0MT58;Q15560-2;Q15560 Q86VL0 TCEA2 Transcription elongation factor A protein 2 1 APS(0.958)T(0.042)PR 84.916 0.041893 3773100.0 14232.0 10506.0 16504.0 14271.0 19397.0 15896.0 14588.0 11220.0 19762.0 11914.0 True False 14029.049070170844 10481.674002486714 15147.104827282332 15320.536946660428 18256.106595969275 15216.165135385849 15343.29526036781 11741.322160623782 17536.195456914375 13973.319025592884 1.003988318342685 0.7501205678685905 1.0840019325072014 1.0964135949805514 1.3064975159110184 1.088944230609537 1.0980422927627818 0.8402672363751891 1.2549771049237401 1.0 13.77038711848156 -5.351330870614484 7.883039755337354 1.098488347067046 0.8778051258153534 0.3032222599090115 0.13288247913138865 0.31990889545257084 24.914188736415912 0.03455546745482159 0.07232065472634511 4.453168510358931e-06 5.351330870614484 -0.22068322125169249 APS(ph)VANVGSHCDLSLK ddPTM_PC-9_AZD4547_30min_R2 3 APSVANVGSHCDLSLK 16 0 Q60FE5;P21333-2;P21333 Q60FE5 FLNA Filamin-A 1 APS(1)VANVGSHCDLSLK;APS(1)VANVGSHCDLSLK;APS(1)VANVGSHCDLSLK 124.45 2.0002999999999998e-05 339160000.0 1087385.0 1584137.0 1470061.0 1187167.0 1120962.0 1329513.0 1589742.0 1801962.0 1627223.0 1381952.0 True False 1433150.8109869424 2096178.3057625503 1450567.0306192047 913483.9896973113 965335.7755125759 1246378.341936626 1731225.9582616747 1523510.177867389 1713234.6857384034 1333570.2811134525 1.0746721273590065 1.5718543937649578 1.087731971207447 0.6849912619038017 0.7238731915250671 0.9346176647667745 1.29818876648646 1.1424296112802903 1.284697709600992 1.0 20.346862428365235 -5.504400061212769 24.19248489336938 1.0030087446988516 1.3248958502006967 0.23621673494671513 0.22209383123554388 712.9762129086935 933433.1567101812 0.0638234791993513 0.12895883798773902 3.1304007488737076e-06 5.504400061212769 0.32188710550184507 APS(ph)VANVGSHCDLSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 APSVANVGSHCDLSLK 16 0 Q60FE5;P21333-2;P21333 Q60FE5 FLNA Filamin-A 1 APS(1)VANVGSHCDLSLK;APS(0.936)VANVGS(0.064)HCDLSLK;APS(1)VANVGSHCDLSLK;APS(1)VANVGSHCDLSLK 107.83 0.00048919 197225800.0 528669.0 1261135.0 953963.0 594744.0 699192.0 385632.0 525794.0 451699.0 386026.0 292325.0 True False 618162.2200112925 1386332.1482491451 976709.0958448242 561422.421866064 562190.3467917682 365408.7790536627 475986.9859010922 439842.37986465154 391670.89996055793 345321.20845657296 1.790107890488955 4.0146162885431 2.828407499818111 1.6257976866679116 1.6280214855742587 1.0581706831354842 1.378389088896495 1.2737195662859653 1.1342219660099846 1.0 18.397579416781923 -5.813443483986585 3.0696392008939757 1.2774362979870504 3.0290015610108036 0.6559229149306602 0.5280288012046426 0.13794036524501496 2.6404393434535374 0.14712049254764803 0.24646403584406995 1.5365847405959471e-06 5.813443483986585 1.7515652630237533 APS(ph)VANVGSHCDLSLK ddPTM_PC-9_Lapatinib_30min_R1 2 APSVANVGSHCDLSLK 16 0 Q60FE5;P21333-2;P21333 Q60FE5 FLNA Filamin-A 1 APS(1)VANVGSHCDLSLK;APS(1)VANVGSHCDLSLK 127.67 1.346e-05 259770000.0 96560.0 388420.0 443050.0 365160.0 447260.0 428620.0 521190.0 473940.0 532440.0 486690.0 True False 95183.03669306471 387520.6373544529 406624.13922245655 392015.08453805075 420953.04614699294 410288.9217620213 548174.6679977437 495960.9826030336 472471.000358238 570813.7180263385 0.16674973583706476 0.6788915982859612 0.7123587369771203 0.6867653529657506 0.7374613343254819 0.7187790145980509 0.9603389874600908 0.8688666143446625 0.8277148664048701 1.0 19.122660481098343 -4.751060018946964 2.038540701524182 0.8066024376149885 1.1287924620958492e-94 0.7848099960789889 0.10127993561710853 0.39677091372559714 1.711311845593605 0.028595573477313126 0.619655600918188 1.773944307094301e-05 4.751060018946964 -0.8066024376149885 down APS(ph)VASSWQPWTPVPQAGEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APSVASSWQPWTPVPQAGEK 20 0 A0A087WZ32;A0A087X038;A8K727;Q9HB19 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 APS(0.993)VAS(0.003)S(0.004)WQPWTPVPQAGEK 84.68 0.0025065 0.0 19163.0 16544.0 16193.0 17844.0 18107.0 16813.0 16782.0 17475.0 14222.0 12151.0 True False 22406.917413497667 18186.37898451301 16579.10253229447 16844.25853102855 14559.063332187097 15931.296682405073 15192.287468841649 17016.299766292992 14429.969844619392 14353.880112736933 1.5610355693033036 1.2670008974350637 1.1550258468149655 1.1734986218870378 1.0142946170539695 1.109894785053166 1.0584098062349534 1.1854843173166507 1.005300987000368 1.0 13.809153155665722 -1.5228787640764359 0.7238659110053326 1.0737110199005282 73.71591851240629 0.8687129578166823 0.058000549762471626 103.45751818822679 0.49842283215003497 0.021148028836161865 12210.063117702799 0.029999998701611557 1.5228787640764359 72.64220749250576 APS(ph)VATVGSICDLNLK ddPTM_PC-9_AZD4547_30min_R2 3 APSVATVGSICDLNLK 16 0 O75369-2;O75369-9;O75369;O75369-8;E7EN95;O75369-7;O75369-5;O75369-4;A0A0C4DGA1 O75369-2 FLNB Filamin-B 1 APS(0.996)VAT(0.004)VGSICDLNLK;APS(1)VATVGSICDLNLK;APS(0.985)VAT(0.015)VGSICDLNLK 270.79 1.4020999999999996e-69 140770400.0 280709.0 286856.0 338440.0 313612.0 284259.0 351581.0 334992.0 340667.0 339213.0 334182.0 True False 369968.6228900829 379576.59222518187 333952.06446723215 241313.59865709982 244794.54451750283 329596.5844910282 364805.6390345068 288024.7428988788 357143.1066629357 322482.3898970837 1.1472521740122115 1.1770459538777267 1.0355668245134528 0.7483000815458857 0.7590943015388406 1.0220607227458682 1.1312420475143776 0.8931487483418812 1.1074809597414406 1.0 18.298860854501946 -5.519042695181067 24.83718307901421 0.9451305129515254 1.1481884397481228 0.321314547349728 0.12116580206876199 172.93388237619357 1119689.0423781052 0.03565638742873985 0.06362906432992173 3.026615869025612e-06 5.519042695181067 0.2030579267965974 APS(ph)VATVGSICDLNLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APSVATVGSICDLNLK 16 0 O75369-2;O75369-9;O75369;O75369-8;E7EN95;O75369-7;O75369-5;O75369-4;A0A0C4DGA1 O75369-2 FLNB Filamin-B 1 APS(0.999)VAT(0.001)VGSICDLNLK;APS(1)VATVGSICDLNLK 233.48 6.980499999999999e-37 93523000.0 125965.0 184350.0 158802.0 141594.0 168144.0 98072.0 148778.0 146303.0 106802.0 88365.0 True False 147288.38657784462 202651.04967329424 162588.44193993852 133660.94723394155 135197.39023180364 92928.93167411107 134684.67078055762 142462.701270842 108363.77720046678 104384.87500304512 1.4110127216567334 1.9413832671388696 1.5575862109831093 1.2804627799769113 1.2951817993541657 0.8902528423912003 1.2902699818975554 1.3647829847637032 1.0381176123198461 1.0 16.671553160109944 -5.7905455795708605 2.341985552231268 1.16332720967257 1.6926012867600198 0.5921331570988497 0.18296265660207905 0.19755589721045894 2.2107532159542855 0.05383394637790369 0.09786132419113636 1.619773988341324e-06 5.7905455795708605 0.5292740770874498 APS(ph)VATVGSICDLNLK ddPTM_PC-9_Lapatinib_30min_R1 4 APSVATVGSICDLNLK 16 0 O75369-2;O75369-9;O75369;O75369-8;E7EN95;O75369-7;O75369-5;O75369-4;A0A0C4DGA1 O75369-2 FLNB Filamin-B 1 APS(0.928)VAT(0.071)VGSICDLNLK;APS(0.955)VAT(0.04)VGS(0.005)ICDLNLK;APS(1)VATVGSICDLNLK;APS(0.994)VAT(0.006)VGSICDLNLK 185.86 6.2835e-08 87636100.0 80177.0 108767.0 120834.0 117993.0 117491.0 127526.0 129491.0 121793.0 115982.0 130996.0 True False 79033.6612773388 108515.15669412437 110899.4949527289 126670.59883310918 110580.41037619344 122072.01025762546 136195.41037567076 127451.94740720607 102918.88581539539 153638.4840588018 0.5144131807958374 0.7063019227174393 0.7218210699754399 0.8244718086689058 0.7197442167801602 0.794540580151162 0.8864667678154446 0.8295574392573841 0.6698769936834668 1.0 17.229180108507997 -4.117161307805312 0.710063156154529 0.8184559954220104 5.902923793114717e-29 0.542878555608855 0.08491193141767052 5.447931096869312 1.05624523980673 0.033043300656269474 4.444334460318642 7.635521285931046e-05 4.117161307805312 -0.8184559954220104 APS(ph)YSGLSMVSGVK ddPTM_PC-9_AZD4547_30min_R2 1 APSYSGLSMVSGVK 14 0 A0A2R8Y7K2;A0A2R8Y5N9;A0A2R8Y481;A0A2R8YFW8;A0A2R8YGN6;A0A2R8YCL5;A0A2R8Y4I8;A0A2U3TZR0;Q9UBP0-4;Q9UBP0-3;Q9UBP0-2;Q9UBP0 A0A2R8Y7K2 SPAST Spastin 1 APS(0.953)Y(0.016)S(0.004)GLS(0.026)MVSGVK 64.39399999999999 0.036404 19303000.0 20801.0 19120.0 32643.0 56548.0 48592.0 41496.0 35614.0 51975.0 40102.0 45764.0 True False 27415.285312322056 25300.16608802142 32210.13249144269 43511.732257890915 41845.839558974345 38901.24856018876 38783.57700654017 43943.45801668268 42221.70985014438 44161.81628947747 0.6207916162826471 0.5728968646167242 0.7293661175597406 0.9852794996626655 0.9475570317279962 0.8808797243572122 0.8782151701441956 0.9950554961018027 0.9560682371708665 1.0 15.430511888122421 -5.585722331322772 3.475249426912568 0.9427600459378767 0.602615071808065 0.9184388507590612 0.04310383469331035 0.061761382684681364 1.504762372566051 0.012869272351547044 0.024864745907143545 2.595838495960481e-06 5.585722331322772 -0.3401449741298117 APS(ph)YSGLSMVSGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APSYSGLSMVSGVK 14 0 A0A2R8Y7K2;A0A2R8Y5N9;A0A2R8Y481;A0A2R8YFW8;A0A2R8YGN6;A0A2R8YCL5;A0A2R8Y4I8;A0A2U3TZR0;Q9UBP0-4;Q9UBP0-3;Q9UBP0-2;Q9UBP0 A0A2R8Y7K2 SPAST Spastin 1 APS(0.993)Y(0.002)S(0.001)GLS(0.004)MVSGVK;APS(0.996)Y(0.003)S(0.001)GLS(0.001)MVSGVK 106.32 0.00078097 51736000.0 99300.0 80038.0 104833.0 125298.0 131052.0 101906.0 99559.0 98074.0 92008.0 75356.0 True False 116109.5287356009 87983.6436872855 107332.61630136664 118277.95928159662 105373.30136465377 96561.86996473983 90128.05077525954 95499.66141799257 93353.44293796539 89017.44628223222 1.3043457612508058 0.9883865170466807 1.2057480952786004 1.3287053742992485 1.1837376353233597 1.0847521918185319 1.0124762565026424 1.0728196034203037 1.0487095152335169 1.0 16.441800493136697 -6.84005340324715 3.485025999213593 1.0407131350349734 1.1984942987986513 0.45914992647390807 0.08723475184822842 0.24770509036160784 5.965347761812638 0.03319062524551495 0.02958313356502089 1.4452620424191788e-07 6.84005340324715 0.1577811637636779 APS(ph)YSGLSMVSGVK ddPTM_PC-9_Lapatinib_30min_R1 3 APSYSGLSMVSGVK 14 0 A0A2R8Y7K2;A0A2R8Y5N9;A0A2R8Y481;A0A2R8YFW8;A0A2R8YGN6;A0A2R8YCL5;A0A2R8Y4I8;A0A2U3TZR0;Q9UBP0-4;Q9UBP0-3;Q9UBP0-2;Q9UBP0 A0A2R8Y7K2 SPAST Spastin 1 APS(0.985)Y(0.003)S(0.006)GLS(0.006)MVSGVK;APS(1)YSGLSMVSGVK;APS(0.991)YS(0.008)GLS(0.001)MVSGVK 184.51 6.5202e-06 47900000.0 151789.0 118262.0 145707.0 130832.0 107021.0 109512.0 81083.0 88117.0 110122.0 81880.0 True False 149624.46102530617 117988.17160499564 133727.5329052851 140453.82172275774 100726.23519138138 104828.42704494062 85281.08099783394 92211.23750692366 97718.90072393113 96032.84890175823 1.5580550065568943 1.2286230488246552 1.3925186478856688 1.46256018986214 1.0488727174430126 1.091589266003972 0.8880407274502148 0.960205164810386 1.0175570322181917 1.0 16.55124035664877 -6.343383490998951 4.387849569693282 0.9911988021491951 1.3962088163608362 0.8293657080558097 0.09100244787733051 0.09243750857015187 3.2586693263846596 0.02902944619672821 0.03339568092197239 4.535409537482537e-07 6.343383490998951 0.40501001421164107 APSASVDSS(ph)LYNLPR ddPTM_PC-9_AZD4547_30min_R2 1 APSASVDSSLYNLPR 15 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 APSASVDS(0.002)S(0.5)LY(0.498)NLPR 184.98 4.5357e-07 8795300.0 10010.0 13939.0 16290.0 24391.0 20044.0 19488.0 16769.0 17687.0 12549.0 14679.0 True False 13192.971779065621 18444.509157998444 16073.983956303076 18768.031787193486 17261.23658462466 18269.412279278935 18261.40851414253 14953.880556826663 13212.314520708735 14165.092677939876 0.9313720763445342 1.302110023376208 1.134760239256043 1.3249494524255414 1.2185756194526416 1.2897488703149083 1.2891838358800212 1.0556853313155665 0.93273759805928 1.0 13.790052420415963 -7.932641716974569 4.659221481010716 0.9731294866445819 1.220185889308882 0.46047394400500763 0.10991742257588623 0.16867166674189277 7.047195350717668 0.06270220438064124 0.028183040955768415 1.1677726055045568e-08 7.932641716974569 0.24705640266430007 APSASVDSS(ph)LYNLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 APSASVDSSLYNLPR 15 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 APSASVDS(0.119)S(0.779)LY(0.102)NLPR;APSASVDS(0.006)S(0.768)LY(0.226)NLPR;APSASVDS(0.128)S(0.729)LY(0.143)NLPR 167.18 1.0078e-10 9331600.0 19655.800000000003 25486.9 37827.0 30995.7 48044.0 36214.7 35267.4 30841.7 28902.4 25312.2 True False 22983.138720253995 28017.070994945883 38728.939139696384 29259.11141841524 38630.12308673974 34315.53737966423 31926.61655813527 30032.138054482333 29325.04292203121 29901.101488735054 0.7686385308886586 0.9369912678802498 1.2952345302157893 0.9785295511417305 1.2919297672459744 1.147634557629667 1.0677404834120678 1.0043823323965724 0.9807345369226325 1.0 14.867911010563654 -5.004716504969021 5.691634988812631 1.101102027881915 0.8017786211445818 0.45571359203099204 0.11306235472311224 0.12302989034483403 15.419748747357081 0.028628251754636687 0.09831317912020489 9.891986045386956e-06 5.004716504969021 -0.29932340673733326 APSASVDSSLY(ph)NLPR ddPTM_PC-9_AZD4547_30min_R2 1 APSASVDSSLYNLPR 15 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 APSASVDS(0.073)S(0.073)LY(0.853)NLPR 136.01 4.0213e-05 5590400.0 2853.5 2871.5 7561.7 14977.0 7122.6 10276.0 3498.3 9791.6 3868.4 4600.3 True False 3760.853643512862 3799.6562197569824 7461.426917272986 11524.284042343363 6133.7499350253265 9633.440095539325 3809.6419228949144 8278.53320858393 4072.875726504878 4439.244897222342 0.8471831878133255 0.8559239933202258 1.680787406421673 2.5960009661900307 1.381710195547726 2.1700627738665683 0.8581734081124082 1.8648516583898878 0.9174703853471334 1.0 12.116098583832537 -8.280454387621983 23.814821085645907 0.9587347972924776 1.5435579810446538 0.1455187665096055 0.5549177268392296 1036.0494128091548 1297549.5685771317 0.5486777016582083 0.14280408979735457 5.24258659107165e-09 8.280454387621983 0.5848231837521762 APSASVDSSLY(ph)NLPR ddPTM_PC-9_Lapatinib_30min_R1 3 APSASVDSSLYNLPR 15 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 APSASVDS(0.016)S(0.098)LY(0.886)NLPR;APSASVDS(0.059)S(0.059)LY(0.882)NLPR;APSASVDSS(0.012)LY(0.988)NLPR 244.73 6.193899999999999e-40 15724200.0 22370.7 21134.4 24726.800000000003 15264.5 26596.5 22876.0 19450.5 16856.699999999997 22592.3 12379.2 True False 22051.689715716067 21085.464595293655 22693.857952208255 16387.102250879263 25032.146160730863 21897.646806560555 20457.551717972572 17639.923820408818 20047.71726653409 14518.92822575285 1.5188235228411717 1.4522741808099482 1.5630532501672663 1.1286716206649987 1.7241042707498384 1.5082137239110909 1.409026300005129 1.2149604672003353 1.380798703238617 1.0 13.825647338361001 -8.70538927726182 0.6449932271940475 0.9999389557069276 1.4807674642115283 0.4581034086369796 0.1522039238599382 0.932000318907172 0.8349411047487744 0.15909030602143756 0.0621855316815129 1.970655558907886e-09 8.70538927726182 0.4808285085046007 APSDS(ph)S(ph)LGTPSDGRPELR ddPTM_PC-9_Lapatinib_30min_R1 1 APSDSSLGTPSDGRPELR 18 1 Q15642;M0R2H7;M0R0F9;W4VSQ9;Q15642-5;Q15642-4;Q15642-2;Q15642-3 Q15642 TRIP10 Cdc42-interacting protein 4 2 APS(0.4)DS(0.707)S(0.892)LGT(0.001)PS(0.001)DGRPELR 81.788 0.009547 11667000.0 23378.0 23527.0 27324.0 24231.0 26885.0 23748.0 21055.0 22482.0 32003.0 18922.0 True False 23044.62543299986 23472.52467699457 25077.52619369017 26013.028572246407 25303.677157943705 22732.353399291835 22145.124877093793 23526.5957945761 28398.48513346983 22192.642488019857 1.0383903334377564 1.0576714643001899 1.12999279861457 1.172146515958561 1.140183156269167 1.024319362219408 0.9978588574591009 1.060107907712042 1.279635138032798 1.0 14.437793839666007 -10.893924067403672 3.54680196666662 0.9994339831609598 1.0965646076600626 0.12301062401985174 0.07964651919017562 9785508.597060129 10220102.847389316 36958.78365815234 0.020019378863278335 1.2766620024977407e-11 10.893924067403672 0.09713062449910281 APSDS(ph)SLGTPSDGRPELR ddPTM_PC-9_AZD4547_30min_R2 3 APSDSSLGTPSDGRPELR 18 1 Q15642;M0R2H7;M0R0F9;W4VSQ9;Q15642-5;Q15642-4;Q15642-2;Q15642-3 Q15642 TRIP10 Cdc42-interacting protein 4 1 APS(0.219)DS(0.637)S(0.14)LGT(0.004)PS(0.001)DGRPELR;APS(0.031)DS(0.434)S(0.148)LGT(0.364)PS(0.023)DGRPELR;APS(0.01)DS(0.631)S(0.359)LGTPSDGRPELR 255.23 1.7665999999999995e-64 80102000.0 66068.9 82686.8 118813.7 157464.3 153148.0 117991.1 109837.4 144584.0 94670.6 118757.2 True False 87077.4358815094 109413.6910714962 117238.15270650745 121163.33843418349 131886.04372690592 110613.09786461566 119612.71581676185 122241.86500979404 99674.6946421396 114599.54657487868 0.759841015816005 0.9547480277333028 1.0230245774131812 1.0572758972917582 1.150842631307728 0.9652140970064109 1.0437451053840565 1.0666871611915316 0.8697651746554924 1.0 16.806241810368732 -4.742316596454484 2.1401175389167326 1.0291131485229932 0.6688032360428424 0.5654872262635169 0.0690202259244193 0.5481391637895953 2.629150125233647 0.01821503019761919 0.39899658808889227 1.8100201244849103e-05 4.742316596454484 -0.36030991248015076 APSDS(ph)SLGTPSDGRPELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 APSDSSLGTPSDGRPELR 18 1 Q15642;M0R2H7;M0R0F9;W4VSQ9;Q15642-5;Q15642-4;Q15642-2;Q15642-3 Q15642 TRIP10 Cdc42-interacting protein 4 1 APS(0.098)DS(0.759)S(0.137)LGT(0.001)PS(0.006)DGRPELR;APS(0.082)DS(0.268)S(0.268)LGT(0.203)PS(0.179)DGRPELR;APS(0.012)DS(0.484)S(0.484)LGT(0.02)PS(0.001)DGRPELR;APS(0.146)DS(0.838)S(0.016)LGTPSDGRPELR 224.36 3.7827e-34 62145900.0 69194.7 72312.9 95617.9 116305.0 126063.0 122174.0 118599.0 112165.0 105403.0 96436.7 True False 80907.99605237928 79491.64681269281 97897.79336890492 109788.80791589775 101361.86010081749 115766.98036496495 107364.44413759679 109220.78759864098 106944.31947211496 113919.9103175029 0.7102182210895615 0.6977853703636522 0.8593563065144346 0.9637367832357708 0.8897642196023046 1.0162137596695269 0.9424554833159932 0.9587506459075931 0.9387675883351165 1.0 16.797660390104596 -5.433512746228819 2.4017063746961362 0.9563881743568865 0.6968646594512242 0.9003833887663493 0.033541607415318926 0.08052214362456679 0.8942233246270547 0.009095806109442729 0.02385833598786118 3.6854222524609085e-06 5.433512746228819 -0.2595235149056623 APSDS(ph)SLGTPSDGRPELR ddPTM_PC-9_Lapatinib_30min_R1 3 APSDSSLGTPSDGRPELR 18 1 Q15642;M0R2H7;M0R0F9;W4VSQ9;Q15642-5;Q15642-4;Q15642-2;Q15642-3 Q15642 TRIP10 Cdc42-interacting protein 4 1 APS(0.061)DS(0.697)S(0.222)LGT(0.019)PS(0.001)DGRPELR;APS(0.131)DS(0.414)S(0.414)LGT(0.037)PS(0.005)DGRPELR;APS(0.099)DS(0.439)S(0.439)LGT(0.004)PS(0.018)DGRPELR 128.71 0.00020451 195246900.0 271415.0 209476.0 231305.0 234844.0 284585.0 263034.0 242081.0 271400.0 286129.0 284216.0 True False 267544.5723285849 208990.9711921675 212287.99576312 252115.2111766179 267846.26981563715 251784.648982202 254614.76966856985 284010.23479441146 253902.13894805487 333342.3569059855 0.802611989702953 0.6269559414290409 0.6368467473906799 0.7563251592647838 0.8035170576632702 0.7553334995264772 0.7638236317516058 0.8520076399247172 0.76168579746277 1.0 18.346645122864956 -14.522878745140591 0.11132302739989572 1.8464236326978334 0.6032433511720361 0.6488663806093844 0.059304978065199264 100.81288926689736 0.7409649890381311 19.19508649724755 0.7314569334694553 3.000000000965332e-15 14.522878745140591 -1.2431802815257973 APSDSSLGT(ph)PSDGRPELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APSDSSLGTPSDGRPELR 18 1 Q15642;M0R2H7;M0R0F9;W4VSQ9;Q15642-5;Q15642-4;Q15642-2;Q15642-3 Q15642 TRIP10 Cdc42-interacting protein 4 1 APS(0.001)DS(0.004)S(0.004)LGT(0.984)PS(0.006)DGRPELR 65.416 0.010793 7919000.0 11821.0 9224.1 13303.0 12171.0 18854.0 14837.0 12088.0 11102.0 8860.6 9279.7 True False 13822.061824607614 10139.807688046818 13620.19397190844 11489.098328914399 15159.69404457145 14058.921600954263 10942.93713045869 10810.584263541337 8990.16951239169 10962.036151935214 1.260902776914077 0.9249930895599864 1.2424875983923809 1.0480806822449804 1.3829268426463994 1.2825100561698415 0.9982577122341315 0.9861839637915134 0.8201185790474324 1.0 13.42022817725155 -7.435412307410254 4.56769378634836 0.9371001415562076 1.1823462512190863 0.4580091773867667 0.12840850563168243 0.22077323271752353 8.007278497596898 0.05804794869331548 0.03754980022900551 3.6693377810163324e-08 7.435412307410254 0.24524610966287874 APSDT(ph)GSLSPPWDQDRR ddPTM_PC-9_AZD4547_30min_R2 1 APSDTGSLSPPWDQDRR 17 1 Q96PC5;Q96PC5-11;Q96PC5-13;G3V599;Q96PC5-10;Q96PC5-9;Q96PC5-6;Q96PC5-12;Q96PC5-7;Q96PC5-14;Q96PC5-5;Q96PC5-8 Q96PC5 MIA2 Melanoma inhibitory activity protein 2 1 APS(0.048)DT(0.416)GS(0.128)LS(0.408)PPWDQDRR 55.536 0.044061 7340300.0 12331.0 8754.8 14758.0 17788.0 13546.0 12839.0 9912.6 15221.0 12963.0 9102.7 True False 16252.001499266547 11584.617890554913 14562.299277294094 13687.251421860436 11665.371720980133 12036.175300372644 10794.802196749304 12868.94419378407 13648.197715510985 8784.01724364625 1.850178688005436 1.318829138106989 1.6578177015564777 1.5581995164867013 1.3280224067658855 1.3702358461418982 1.2289140489287536 1.4650408619236912 1.5537535203933195 1.0 13.100665171120239 -9.28231167837487 0.052261142597527274 2.68971192217708e-16 2.51330426142104 0.4794122706715245 0.16341994287829786 97.8450171303808 1.8230779492940552 50.29541142378223 36.56893456325259 5.220214175227619e-10 9.28231167837487 2.5133042614210397 APSDTGSLS(ph)PPWDQDRR ddPTM_PC-9_AZD4547_30min_R2 1 APSDTGSLSPPWDQDRR 17 1 Q96PC5;Q96PC5-11;Q96PC5-13;G3V599;Q96PC5-10;Q96PC5-9;Q96PC5-6;Q96PC5-12;Q96PC5-7;Q96PC5-14;Q96PC5-5;Q96PC5-8 Q96PC5 MIA2 Melanoma inhibitory activity protein 2 1 APS(0.016)DT(0.045)GS(0.017)LS(0.922)PPWDQDRR 52.498000000000005 0.030943000000000002 7871500.0 10034.0 11075.0 12369.0 13630.0 15136.0 17338.0 12979.0 19892.0 12557.0 16443.0 True False 13224.603279834602 14654.77716657098 12204.978978238976 10487.814081400815 13034.627666377914 16253.852119157329 14134.105856345379 16818.148472685938 13220.737384376422 15867.335574859679 0.8334482634115181 0.9235814732367617 0.7691889366464671 0.660968820626557 0.8214755152106363 1.0243592594657196 0.8907674379017709 1.0599226564120023 0.8332046248094389 1.0 13.953772272331566 -6.665155738224182 6.530751055608008 0.9604818847798847 0.7967537932489618 0.4666049500434103 0.08568160747223356 0.2031886367738898 11.676533607302217 0.02905105362387066 0.028952979357297504 2.1619431107940974e-07 6.665155738224182 -0.16372809153092294 APSEEELHGDQT(ph)DFGQGSQSPQKQEEQR ddPTM_PC-9_AZD4547_30min_R2 2 APSEEELHGDQTDFGQGSQSPQKQEEQR 28 1 Q8TE77;C9JUG3;Q8TE77-4;Q8TE77-2;A0A087WWG1 Q8TE77 SSH3 Protein phosphatase Slingshot homolog 3 1 APSEEELHGDQT(0.384)DFGQGS(0.308)QS(0.308)PQKQEEQR;APSEEELHGDQT(0.887)DFGQGS(0.075)QS(0.037)PQKQEEQR 64.257 0.00021046 17506800.0 18595.0 21058.0 26342.0 26251.0 25048.0 35850.0 25425.0 26819.0 29226.0 22820.0 True False 24507.82319997254 27864.586688365827 25992.687868442972 20199.237523907028 21570.51755995205 33608.29383272525 27687.7757452486 22674.73978931048 30770.82669393847 22021.07874586742 1.112925641963466 1.2653597496260272 1.1803548848995822 0.9172683026574123 0.979539549759799 1.5261874416135195 1.257330581520427 1.0296834251848688 1.3973351191849794 1.0 14.42659752343781 APSEEELHGDQTDFGQGS(ph)QSPQKQEEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APSEEELHGDQTDFGQGSQSPQKQEEQR 28 1 Q8TE77;C9JUG3;Q8TE77-4;Q8TE77-2;A0A087WWG1 Q8TE77 SSH3 Protein phosphatase Slingshot homolog 3 1 APSEEELHGDQT(0.013)DFGQGS(0.809)QS(0.177)PQKQEEQR;APSEEELHGDQT(0.023)DFGQGS(0.755)QS(0.223)PQKQEEQR 73.11 2.5828e-05 25967000.0 40469.0 54104.0 43881.0 52384.0 53524.0 43754.0 49463.0 33553.0 37911.0 33553.0 True False 47319.602400815966 59475.087559120686 44927.289459619205 49449.0943112194 43036.356425248894 41459.4632154851 44777.50655889134 32672.269302342138 38465.376654434374 39635.89329459814 1.1938573466506182 1.5005360700985226 1.1335001112676375 1.2475836975259662 1.0857925190527795 1.0460080439548334 1.1297211400302647 0.8243101539178617 0.9704682664406281 1.0 15.27451987107386 -6.3574649943323145 0.6669407471773136 0.9411141869812655 1.349884571629125 0.6028927634949663 0.10863507217259971 0.5240055403669758 0.5072552081289906 0.0702888987350984 0.11664123757471774 4.390712549071205e-07 6.3574649943323145 0.40877038464785953 APSEEELHGDQTDFGQGS(ph)QSPQKQEEQR ddPTM_PC-9_Lapatinib_30min_R1 2 APSEEELHGDQTDFGQGSQSPQKQEEQR 28 1 Q8TE77;C9JUG3;Q8TE77-4;Q8TE77-2;A0A087WWG1 Q8TE77 SSH3 Protein phosphatase Slingshot homolog 3 1 APS(0.002)EEELHGDQT(0.24)DFGQGS(0.581)QS(0.177)PQKQEEQR;APSEEELHGDQTDFGQGS(0.5)QS(0.5)PQKQEEQR 95.926 7.004500000000001e-10 15631600.0 19875.7 29227.5 31588.3 27941.9 33188.4 33038.0 28261.5 33746.9 32667.8 30593.8 True False 19592.26887324302 29159.825519482256 28991.231908364174 29996.840537445933 31236.3235629049 31625.041755339586 29724.74218541846 35314.90417311541 28988.408356815464 35881.897566323954 0.5460209799949612 0.812661188433063 0.8079626183307864 0.8359881325116626 0.8705315404562373 0.88136480789189 0.8284049674484291 0.9841983442441827 0.8078839281906262 1.0 15.130968566828269 -4.27485160966754 1.0462646452009534 0.883236807105439 3.768974582827587e-32 0.7176919797496315 0.0624966234445481 2.3748764352570757 1.0203212209536692 0.018431266066040623 3.019380412115811 5.3106586854674864e-05 4.27485160966754 -0.883236807105439 APSEEELHGDQTDFGQGSQS(ph)PQKQEEQR ddPTM_PC-9_Lapatinib_30min_R1 2 APSEEELHGDQTDFGQGSQSPQKQEEQR 28 1 Q8TE77;C9JUG3;Q8TE77-4;Q8TE77-2;A0A087WWG1 Q8TE77 SSH3 Protein phosphatase Slingshot homolog 3 1 APSEEELHGDQT(0.035)DFGQGS(0.394)QS(0.571)PQKQEEQR;APSEEELHGDQT(0.008)DFGQGS(0.254)QS(0.738)PQKQEEQR 90.912 6.681499999999999e-08 36061600.0 68572.0 86435.0 78459.0 74403.0 95744.0 87442.0 87332.0 92127.0 82561.0 71930.0 True False 67594.1507054354 86234.86506805054 72008.40388049839 79874.8448211322 90112.52615994638 83702.30949725787 91853.62364124213 96407.55674614853 73262.11077412756 84363.00465929972 0.8012297686458016 1.0221881666769732 0.8535542821323703 0.9467994311452872 1.0681521660337505 0.9921684254287756 1.088790329507505 1.142770544215332 0.868415143225361 1.0 16.36432285839225 -6.0877020296516795 4.5943212147593835 1.034657096897293 0.9042987991335123 0.3300354917145806 0.08580884212688349 0.25791803273087127 9.445589112890524 0.024630556226168006 0.03276203725607599 8.171428224652172e-07 6.0877020296516795 -0.13035829776378072 APSGSSLPS(ph)SPGSNSR ddPTM_PC-9_Lapatinib_30min_R1 1 APSGSSLPSSPGSNSR 16 0 Q96Q07-3;Q96Q07-2;Q96Q07 Q96Q07-3 BTBD9 BTB/POZ domain-containing protein 9 1 APSGS(0.001)S(0.003)LPS(0.497)S(0.497)PGS(0.001)NSR 73.758 0.013974 4437800.0 11973.0 10103.0 11334.0 11479.0 12912.0 9405.1 7047.4 10055.0 15126.0 10445.0 True False 11802.262824420704 10079.607124226472 10402.162270505205 12323.203952821454 12152.541545968723 9002.865797358923 7412.279888806972 10522.192007582182 13422.350596158629 12250.40433291235 0.9634182271610697 0.8227979134652934 0.8491280767409778 1.005942629968018 0.9920114647415591 0.7349035634008846 0.6050641013450381 0.8589260992237542 1.0956659250909528 1.0 13.580541746692464 -8.250090954387533 22.52878103264705 1.047832944781018 0.8502140970605767 0.306104487341634 0.11660737531183032 227.01451952526162 450675.50333847385 0.08924620335718905 0.032894004763172495 5.622235662562266e-09 8.250090954387533 -0.19761884772044125 APSGSSLPSS(ph)PGSNSR ddPTM_PC-9_AZD4547_30min_R2 2 APSGSSLPSSPGSNSR 16 0 Q96Q07-3;Q96Q07-2;Q96Q07 Q96Q07-3 BTBD9 BTB/POZ domain-containing protein 9 1 APSGSS(0.001)LPS(0.04)S(0.897)PGS(0.062)NSR;APSGS(0.001)S(0.028)LPS(0.435)S(0.535)PGS(0.001)NSR 120.54 9.018700000000001e-05 9416600.0 23719.4 20759.6 28308.0 42926.0 34050.0 33291.0 27847.0 36854.0 27278.0 32472.0 True False 31261.675805831073 27469.73472389588 27932.617423881376 33030.073900088886 29322.745245782775 31209.308507259597 30325.329053212874 31159.06112066999 28719.859390859267 31335.165163707585 0.9976547320720164 0.8766424105436453 0.8914143990609298 1.054089669785572 0.9357775870204892 0.9959835330118587 0.9677730720352384 0.9943799867619157 0.9165376739141184 1.0 14.93549497695946 -5.722537400718407 24.999706894251393 0.9786476485191662 0.9173776907358254 0.2516297231587229 0.0461379462374941 208.8315204115277 134200.58987834983 0.011895570246743389 0.020603299589316754 1.8943603681677916e-06 5.722537400718407 -0.06126995778334077 APSGSSLPSS(ph)PGSNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APSGSSLPSSPGSNSR 16 0 Q96Q07-3;Q96Q07-2;Q96Q07 Q96Q07-3 BTBD9 BTB/POZ domain-containing protein 9 1 APS(0.029)GS(0.02)S(0.02)LPS(0.334)S(0.597)PGSNSR 66.568 0.026491000000000004 2373600.0 3586.5 4442.5 5273.8 5549.5 6783.0 5800.6 5584.9 6409.1 6848.2 3958.1 True False 4193.623613396094 4883.522040540319 5399.547392997875 5238.57950672175 5453.919842172921 5496.4063246273 5055.857840825512 6240.8679160027705 6948.341969478454 4675.672197697638 0.8969028272471901 1.0444534676629018 1.1548173534613233 1.1203906700947288 1.1664461518193046 1.1755328629183635 1.0813114408052562 1.3347530904916423 1.4860626826876162 1.0 12.19095807352795 -3.500836003044195 0.45313991975836027 1.2383825584981956 2.224690562949586e-16 0.37009711881547014 0.125779087069696 16.454479621455686 1.0609920681986524 0.08340954189843124 14.00015911131423 0.0003156196231555839 3.500836003044195 -1.2383825584981953 APSGSSLPSS(ph)PGSNSR ddPTM_PC-9_Lapatinib_30min_R1 1 APSGSSLPSSPGSNSR 16 0 Q96Q07-3;Q96Q07-2;Q96Q07 Q96Q07-3 BTBD9 BTB/POZ domain-containing protein 9 1 APSGSS(0.002)LPS(0.159)S(0.839)PGSNSR 165.89 5.2175e-05 3776700.0 14230.0 15572.0 18124.0 14111.0 13598.0 19699.0 14661.0 15353.0 15704.0 12892.0 True False 14027.077590537594 15535.943990740821 16633.91468066318 15148.770012916075 12798.1923746966 18856.519690611836 15420.074843176057 16066.356428882082 13935.250149548801 15120.365022489794 0.9276943757425128 1.027484717970294 1.1001000740340696 1.0018785915805626 0.8464208605850964 1.247094211189012 1.0198215995606243 1.0625640588031595 0.9216212789057492 1.0 13.884205347797538 -4.76256870304475 7.47977218604791 1.0300733697952398 0.9260537473552988 0.07685054088067511 0.10017623328790613 0.26891251946032946 107.50146669778607 0.024503120661962946 0.14299679883526825 1.7275526693751997e-05 4.76256870304475 -0.104019622439941 APSPAPS(ph)SVPLGSEKPSNVSQDR ddPTM_PC-9_AZD4547_30min_R2 1 APSPAPSSVPLGSEKPSNVSQDR 23 1 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 APS(0.155)PAPS(0.684)S(0.161)VPLGSEKPSNVSQDR 69.081 0.00057213 135440000.0 25333.0 23862.0 30185.0 42521.0 35433.0 35762.0 34639.0 47251.0 37431.0 39512.0 True False 33388.36704086607 31574.92485315725 29784.72717747138 32718.440392901244 30513.7395681005 33525.79648663657 37721.80389536545 39949.443669961955 39409.526243098946 38128.6969065168 0.8756755344334746 0.828114449611851 0.7811629977939449 0.8581053916717816 0.8002827802616359 0.8792798917003241 0.989328431229922 1.0477526616739414 1.0335922662062764 1.0 15.21858960564021 -7.237644207689337 2.426980428131326 1.0299035509814265 0.8277009656496769 0.912054611226305 0.027945002741983076 0.07765476120663745 0.8995495730257362 0.012852883402028772 0.008656938001928068 5.785698420584348e-08 7.237644207689337 -0.20220258533174962 APSPAPS(ph)SVPLGSEKPSNVSQDR ddPTM_PC-9_Lapatinib_30min_R1 2 APSPAPSSVPLGSEKPSNVSQDR 23 1 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 APS(0.079)PAPS(0.46)S(0.46)VPLGS(0.002)EKPSNVSQDR;APS(0.255)PAPS(0.372)S(0.372)VPLGS(0.001)EKPSNVSQDR 61.958999999999996 0.0018035 146506000.0 70298.0 38841.0 41990.0 46585.0 40781.0 44684.0 36951.0 37995.0 56623.0 49563.0 True False 69295.53762892574 38751.066050883914 38537.74428608731 50011.0163030044 38382.341758530834 42772.96948349155 38864.14197736845 39760.38640756688 50245.52147337631 58129.89851145377 1.1920808293734062 0.6666288268720871 0.6629590842738858 0.8603320766704995 0.6602857177011598 0.7358170335539751 0.6685740552206667 0.6839920148791003 0.8643662342447761 1.0 15.826992769331184 -4.7557436205011365 24.98140827346639 0.7400257748270557 1.1920815604504214 0.577807669886451 0.11111638664682828 119.46015686646415 523894.1896876011 0.02567467336590563 0.22171643930833368 1.754916185632033e-05 4.7557436205011365 0.4520557856233657 APSPAPSS(ph)VPLGSEKPSNVSQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APSPAPSSVPLGSEKPSNVSQDR 23 1 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 APS(0.008)PAPS(0.2)S(0.792)VPLGSEKPSNVSQDR;APS(0.291)PAPS(0.317)S(0.391)VPLGSEKPSNVSQDR 110.64 4.3181000000000005e-07 110293800.0 21759.4 18069.4 21016.6 26861.0 29460.0 24164.0 27803.0 27727.0 25017.0 18814.0 True False 25442.836652260128 19863.21061549563 21517.71544989934 25356.065254536985 23687.524480379507 22896.797301709154 25169.298563711374 26999.195629184895 25382.826297485837 22224.829268457943 1.1447933455385084 0.8937396267734672 0.9681836107707628 1.1408890906767493 1.0658135634813384 1.0302350144126815 1.1324855754654681 1.2148212840268184 1.1420931963472856 1.0 14.43988471583756 -6.346227559302675 0.9174714291609055 1.128764846094527 1.0020607096593221 0.14423228939505095 0.08703506333185164 0.9046942051678162 1.64158236168542 0.04502183612593532 0.06572180191113262 4.505805498877569e-07 6.346227559302675 -0.12670413643520484 APSPPS(ph)RR ddPTM_PC-9_AZD4547_30min_R2 1 APSPPSRR 8 1 Q7Z2K8 Q7Z2K8 GPRIN1 G protein-regulated inducer of neurite outgrowth 1 1 APS(0.477)PPS(0.523)RR 61.958 0.029262 5132200.0 1070.4 1340.1 4980.3 6077.2 4680.5 3663.3 2628.3 4998.4 3186.2 3837.4 True False 1410.7649342968873 1773.2611179161856 4914.25796792979 4676.195431804039 4030.6933663109044 3434.2332718946277 2862.213608308237 4226.012131805414 3354.616027243779 3703.0537940136546 0.38097338379948076 0.4788645308860579 1.3270825219644835 1.2627943562050226 1.088478210288738 0.927405720501927 0.7729333051913214 1.1412235324901767 0.9059052916451933 1.0 11.854499792257782 -5.172706953536167 6.586137958111758 1.0517834274430664 0.41384521215554865 0.713550714218744 0.15815849854234956 0.13702267903368143 8.49201943659202 0.04405591642327743 0.11942493599235375 6.718820621134363e-06 5.172706953536167 -0.6379382152875177 APSPSSR ddPTM_PC-9_Lapatinib_30min_R1 1 APSPSSR 7 0 Q9UQ35;I3L3Q8 Q9UQ35;REV__O95996-2 SRRM2 Serine/arginine repetitive matrix protein 2 0 88.64299999999999 0.028713 0.0 4433.4 11271.0 8688.4 10418.0 12159.0 7589.1 13458.0 12744.0 8050.5 7725.5 False True 4370.178903014014 11244.902691988174 7974.073290193885 11184.17447342921 11443.83152551376 7264.531884056164 14154.789389500256 13336.132764259304 7143.767914476732 9060.84238141831 0.48231485760929244 1.2410438476502876 0.8800587135857108 1.2343415769338801 1.2629986312290797 0.8017501660722006 1.5621935349552545 1.4718424847129694 0.7884220488292508 1.0 13.145429467715068 -4.756907107959476 24.841791632400763 1.1544105878375022 0.4823137628176301 0.3716870734168415 0.25498318764112105 135.3926901478539 741999.7788146519 0.06267963099146014 0.4857138769773691 1.750221006561548e-05 4.756907107959476 -0.672096825019872 APSPT(ph)AEQPPGGGDSARR ddPTM_PC-9_AZD4547_30min_R2 1 APSPTAEQPPGGGDSARR 18 1 Q15742-2;Q15742-3;Q15742 Q15742-2 NAB2 NGFI-A-binding protein 2 1 APS(0.153)PT(0.847)AEQPPGGGDSARR 114.53 0.00071934 0.0 5168.1 4988.3 7432.0 13447.0 9215.2 5430.9 5903.4 6265.5 4989.9 10023.0 True False 6811.448296842063 6600.670423476842 7333.446824017467 10347.001904078994 7935.828545930619 5091.304964467156 6428.791163598841 5297.310941866767 5253.655926917251 9672.09782076376 0.7042369114815461 0.6824445477905245 0.7582064366919709 1.0697784592155768 0.8204867954182833 0.5263909711021844 0.6646739190124517 0.5476899675781467 0.5431764674297302 1.0 13.239613120317891 -6.741765689958824 24.921831842254296 0.6286348706127213 0.8119938923998306 0.16797703144897114 0.16165785792935286 356.44332373690526 451526.9570228349 0.053531982201180495 0.05345944495948529 1.8123176083375107e-07 6.741765689958824 0.18335902178710928 APSPTGPALIS(ph)GASPVHCAADGTVELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APSPTGPALISGASPVHCAADGTVELK 27 0 E7EWD6;Q76L83 E7EWD6 ASXL2 Putative Polycomb group protein ASXL2 1 APS(0.001)PT(0.001)GPALIS(0.595)GAS(0.403)PVHCAADGTVELK 92.81700000000001 6.1754e-08 6592200.0 20816.0 18647.0 21077.0 27032.0 21763.0 22449.0 22307.0 24033.0 24194.0 19236.0 True False 24339.737665259476 20498.15092627021 21579.555614967634 25517.484678926463 17498.696377002692 21271.73492079411 20193.91947130561 23402.159215068365 24547.791479448868 22723.334527907773 1.0711340642090408 0.9020749530001992 0.9496650057439676 1.1229639139267629 0.7700760799657983 0.9361185478596519 0.888686449011449 1.0298734627317523 1.080290018584217 1.0 14.471886937714501 -7.891188781220415 7.307072124417535 1.0448435687788036 0.9464499568038625 0.15807844201807253 0.0930196127084721 0.3906435122335183 23.536127634194322 0.050902230026460916 0.024281044836059168 1.284728086748534e-08 7.891188781220415 -0.09839361197494112 APSPTGPALIS(ph)GASPVHCAADGTVELK ddPTM_PC-9_Lapatinib_30min_R1 2 APSPTGPALISGASPVHCAADGTVELK 27 0 E7EWD6;Q76L83 E7EWD6 ASXL2 Putative Polycomb group protein ASXL2 1 APSPTGPALIS(0.5)GAS(0.5)PVHCAADGTVELK;APSPTGPALIS(0.631)GAS(0.368)PVHCAADGT(0.001)VELK 98.29899999999999 1.2680999999999998e-09 8880100.0 38971.0 39818.0 49435.0 41744.0 52442.0 51692.0 42401.0 43415.0 51705.0 36263.0 True False 38415.26639359387 39725.80386741061 45370.64512461839 44813.99301390179 49357.46466493891 49481.25365993743 44596.31631031361 45432.21939424968 45881.438422212246 42531.01123258979 0.9032295560411647 0.9340432478823906 1.066766197410625 1.0536780507951486 1.1605053168149992 1.1634158752854187 1.0485599805381833 1.0682139473664056 1.0787760998980236 1.0 15.376227536956076 -5.24272373648691 2.2287227641124283 1.08998673437789 0.8988910885988294 0.6543297245258497 0.04702270915248167 0.20346515866727052 1.8628807326013646 0.013549953500131717 0.05104358922425966 5.718422814520109e-06 5.24272373648691 -0.19109564577906057 APSPTGPALISGAS(ph)PVHCAADGTVELK ddPTM_PC-9_AZD4547_30min_R2 1 APSPTGPALISGASPVHCAADGTVELK 27 0 E7EWD6;Q76L83 E7EWD6 ASXL2 Putative Polycomb group protein ASXL2 1 APSPTGPALIS(0.05)GAS(0.949)PVHCAADGTVELK 98.37 1.2572e-09 5801200.0 22313.0 20174.0 35766.0 43650.0 41849.0 38772.0 28707.0 38262.0 31575.0 30766.0 True False 29408.069860768355 26694.85097592804 35291.719470910735 33587.166885777355 36038.98871632199 36347.58071080679 31261.867387172137 32349.487073291228 33243.9900383599 29688.89170444158 0.9905411813122276 0.8991528293369867 1.188717983218988 1.1313041665597972 1.2138879778705383 1.224282168315803 1.0529819603368769 1.0896158534759859 1.119745067256467 1.0 14.857635617624778 -5.259929304181563 24.99983736707139 1.1347742035839712 0.9448469949965269 0.5222441501993861 0.06963316199874894 96.85160572413719 1603378.3331940332 0.018205359435547516 0.04327560409653931 5.496303371267072e-06 5.259929304181563 -0.18992720858744427 APSQVSISAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 APSQVSISASPR 12 0 Q8IVL1-4;Q8IVL1-11;A0A0A0MTL4;A0A0A0MTE8;Q8IVL1-8;Q8IVL1-9;Q8IVL1-10;Q8IVL1-13;Q8IVL1-12;Q8IVL1-3;Q8IVL1-2;Q8IVL1;Q8IVL1-5;Q8IVL1-7;Q8IVL1-6 Q8IVL1-4 NAV2 Neuron navigator 2 1 APSQVSIS(0.004)AS(0.995)PR;APSQVS(0.001)IS(0.044)AS(0.955)PR 85.271 0.009756200000000001 8936900.0 9650.1 9550.5 15282.5 22302.2 14131.400000000001 15556.900000000001 16257.5 16603.5 14902.3 16007.3 True False 12718.631065450665 12637.512354793334 15079.84406459188 17160.772355555197 12169.499035719677 14584.124583718933 17704.386005049313 14037.810585473593 15690.00515435157 15446.889299242916 0.8233781455321255 0.8181266862197767 0.9762382426946619 1.1109532814737193 0.7878284617677768 0.9441463780305418 1.1461457165953175 0.9087791278572583 1.015738822904659 1.0 13.915028716423285 -5.270143153465451 6.994223222476375 0.9847679569395363 0.820119543983626 0.3288645958480927 0.0945659638660358 0.15170794613249822 48.42266060283384 0.02488099285296252 0.05698163513161496 5.3685480749075035e-06 5.270143153465451 -0.16464841295591037 APSS(ph)SSLNSATSSQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APSSSSLNSATSSQSK 16 0 Q5F1R6;Q5F1R6-3;Q5F1R6-2;A0A2R8Y534;A0A2R8Y4Q0 Q5F1R6 DNAJC21 DnaJ homolog subfamily C member 21 1 APS(0.207)S(0.753)S(0.039)SLNSATSSQSK 163.44 1.8606e-15 0.0 7559.7 8781.9 10081.0 7165.3 10848.0 9152.3 13234.0 8942.6 7966.2 8698.4 True False 8839.407899119047 9653.708994444807 10321.369272405398 6763.851471216031 8722.41227301958 8672.337276296668 11980.379714137196 8707.866225467911 8082.690604430254 10275.351063503482 0.8602536151310011 0.939501622356568 1.0044785047846556 0.6582598910163007 0.8488675685252536 0.8439942560307764 1.165933858619169 0.8474519431649354 0.7866096792681633 1.0 13.32690006483581 APSTSPS(ph)FEGTQETYTVAHEENVR ddPTM_PC-9_AZD4547_30min_R2 1 APSTSPSFEGTQETYTVAHEENVR 24 0 Q9BUT9 Q9BUT9 FAM195A Protein FAM195A 1 APS(0.009)T(0.037)S(0.149)PS(0.803)FEGT(0.002)QETYTVAHEENVR 145.16 2.1112000000000002e-06 7745300.0 5227.4 5393.5 8340.8 7917.4 9370.4 5976.1 10048.0 12104.0 7091.0 8299.6 True False 6889.604463325433 7136.84339935897 8230.195542218096 6092.165752610623 8069.481704877623 5602.413522280317 10942.25253444476 10233.604922249677 7465.8157834365875 8009.033530201627 0.8602291946144452 0.8910992034739676 1.027614069935215 0.7606617864237175 1.0075474992641806 0.6995118076549339 1.3662388218481198 1.2777577823415662 0.9321743697642674 1.0 12.96741244423615 -7.259538690541391 24.98503658466853 1.1671892209530332 0.8830415144137334 0.43780791120256113 0.1485525744208992 152.73396352397677 2007742.961291244 0.05715849950794145 0.04198066236520055 5.5012490865454564e-08 7.259538690541391 -0.2841477065392999 APSTSPS(ph)FEGTQETYTVAHEENVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APSTSPSFEGTQETYTVAHEENVR 24 0 Q9BUT9 Q9BUT9 FAM195A Protein FAM195A 1 APS(0.012)T(0.043)S(0.157)PS(0.78)FEGT(0.008)QETYTVAHEENVR;APS(0.013)T(0.046)S(0.167)PS(0.774)FEGTQETYTVAHEENVR 142.01 7.6685e-09 15084000.0 15633.0 21855.4 14278.3 14546.2 13291.7 13178.0 23339.7 14536.400000000001 18355.300000000003 7534.4 True False 18279.3581341757 24025.05967469328 14618.748822754298 13731.22357341669 10687.286800266815 12486.922481456837 21128.794651205066 14154.834902588933 18623.711537684045 8900.327077722422 2.0537849872876084 2.6993457054885277 1.6424956852816255 1.5427774118308566 1.2007746127686885 1.4029734382134884 2.3739346280981715 1.5903724412576452 2.092474959071933 1.0 13.119642639250964 -5.279529734311107 23.204296475693468 1.6302942316875657 2.3765652288711268 0.36895138414297346 0.40222145440038437 301.8339583765834 387159.49710316455 0.10552880460817106 0.22060426939300873 5.253760435972756e-06 5.279529734311107 0.746270997183561 APSTSPS(ph)FEGTQETYTVAHEENVR ddPTM_PC-9_Lapatinib_30min_R1 1 APSTSPSFEGTQETYTVAHEENVR 24 0 Q9BUT9 Q9BUT9 FAM195A Protein FAM195A 1 APS(0.004)T(0.019)S(0.125)PS(0.852)FEGTQETYTVAHEENVR 213.57 6.8242e-38 6371800.0 2156.1 8289.0 5447.7 3958.5 8602.4 8082.7 11845.0 7094.4 5699.3 9776.6 True False 2125.3536186196857 8269.807329774645 4999.811134730127 4249.621295168895 8096.423744969124 7737.021762693963 12458.276141969885 7424.031723380515 5057.384817710359 11466.47228349936 0.18535374839549745 0.7212163536709696 0.43603743253494137 0.37061279093520705 0.7060954358752648 0.6747517084071094 1.0864959888228016 0.6474556027195868 0.4410584783768331 1.0 13.485133986952599 -6.380280067579187 4.293808651406997 0.7608532767092082 0.45050179848001093 0.3755585308605053 0.20906013234572815 0.28459900302437613 8.672426010528529 0.0668866810694261 0.07621439464336467 4.166006396417412e-07 6.380280067579187 -0.3103514782291973 APSVANVGS(ph)HCDLSLKIPEISIQDMTAQVTSPSGK ddPTM_PC-9_Lapatinib_30min_R1 1 APSVANVGSHCDLSLKIPEISIQDMTAQVTSPSGK 35 1 Q60FE5;P21333-2;P21333 Q60FE5 FLNA Filamin-A 1 APS(0.304)VANVGS(0.317)HCDLS(0.291)LKIPEIS(0.042)IQDMT(0.046)AQVT(0.001)SPSGK 40.163000000000004 0.025889999999999996 2141400.0 3080.9 4021.5 5348.9 5772.2 6551.9 4774.7 4884.9 4229.1 7165.4 6523.5 True False 3036.965801032135 4012.188463830222 4909.134089351097 6196.706843494726 6166.530123531009 4570.497211369327 5137.816220000734 4425.599425088593 6358.3571969929335 7651.078282982644 0.3969330450829246 0.524395165679332 0.6416264358802709 0.8099128795057948 0.8059687661602505 0.597366415859961 0.6715153119565054 0.5784281981445559 0.8310406666645992 1.0 12.901447368923218 -14.522878745280298 0.051261205124672006 2.3342918865350075 3.7874899742054975e-19 0.5593262476196701 0.1112115133534772 490.9094718082811 1.8513021885787626 89.07647363562475 19.110092665098506 3.0000000000002712e-15 14.522878745280298 -2.3342918865350075 APSVATVGSICDLNLK ddPTM_PC-9_Lapatinib_30min_R1 2 APSVATVGSICDLNLK 16 0 O75369-2;O75369-9;O75369;O75369-8;E7EN95;O75369-7;O75369-5;O75369-4;A0A0C4DGA1 O75369-2 FLNB Filamin-B 0 ; 164.22 1.5578e-15 3812300.0 22935.0 20587.6 21028.7 21092.4 20016.1 20380.6 22539.0 17760.5 20673.2 21137.8 False True 22607.942694236102 20539.930677098364 19299.801459129438 22643.605458183738 18838.79235116669 19508.969247499037 23705.95913582602 18585.717667892943 18344.766517552995 24791.440565651938 0.9119253330344574 0.8285089614984311 0.7784864864153533 0.9133638441953235 0.7598909914604749 0.7869235833970994 0.9562154757828057 0.7496828439103734 0.7399637172746353 1.0 14.597554484638415 -4.761769258079009 8.811402808899793 0.8275723478018993 0.9125864950209432 0.06042252726741448 0.08719240753067681 0.2305167323594577 227.30972632452404 0.020645642033362655 0.11778222968697828 1.7307356598683012e-05 4.761769258079009 0.08501414721904399 APSYS(ph)GLSMVSGVK ddPTM_PC-9_Lapatinib_30min_R1 1 APSYSGLSMVSGVK 14 0 A0A2R8Y7K2;A0A2R8Y5N9;A0A2R8Y481;A0A2R8YFW8;A0A2R8YGN6;A0A2R8YCL5;A0A2R8Y4I8;A0A2U3TZR0;Q9UBP0-4;Q9UBP0-3;Q9UBP0-2;Q9UBP0 A0A2R8Y7K2 SPAST Spastin 1 APS(0.173)Y(0.1)S(0.552)GLS(0.173)MVS(0.001)GVK 81.185 0.0094377 11492000.0 77617.0 75005.0 81574.0 63848.0 58740.0 56890.0 46236.0 46746.0 60848.0 46316.0 True False 76510.16734678533 74831.33053079335 74867.30060474621 68543.59491068417 55285.0286872833 54456.94731706728 48629.87384551452 48917.98981466306 53994.65748215396 54321.658887809324 1.4084652220360574 1.3775597443616865 1.3782219125408128 1.2618096780189916 1.0177345430754172 1.0024905062184748 0.8952207064579882 0.9005245939873361 0.9939802757804079 1.0 15.729239917170982 -6.195233709332831 1.6995115036244897 0.944587432501696 1.3961779456413639 0.9667440446764857 0.035988280716147986 0.05835991039430054 0.33370783230539947 0.012789771783969525 0.0180355095126744 6.379201062707085e-07 6.195233709332831 0.4515905131396679 APSYSGLS(ph)MVSGVK ddPTM_PC-9_AZD4547_30min_R2 1 APSYSGLSMVSGVK 14 0 A0A2R8Y7K2;A0A2R8Y5N9;A0A2R8Y481;A0A2R8YFW8;A0A2R8YGN6;A0A2R8YCL5;A0A2R8Y4I8;A0A2U3TZR0;Q9UBP0-4;Q9UBP0-3;Q9UBP0-2;Q9UBP0 A0A2R8Y7K2 SPAST Spastin 1 APS(0.102)Y(0.005)S(0.01)GLS(0.881)MVS(0.001)GVK 79.97399999999999 0.010693000000000001 16903000.0 32590.0 33444.0 47425.0 66449.0 71582.0 68586.0 52668.0 71000.0 48665.0 65245.0 True False 42952.94208588895 44254.118966934526 46796.11351305546 51130.209676816 61644.0748952606 64297.30657772098 57355.34996856452 60028.58141769063 51237.33254843339 62960.79240903243 0.6822173044907051 0.7028837673997537 0.7432580137975207 0.8120960318390275 0.9790867067679578 1.0212277215319292 0.9109693155694186 0.9534279846369732 0.8137974537481015 1.0 15.942166077913708 -5.963069739050849 2.3484312193204353 0.9456899626514617 0.7030125823452903 0.7878060784162917 0.055548734002793886 0.13509640711773688 1.5047662255161796 0.017722043766958927 0.028015313829811955 1.0887552468701749e-06 5.963069739050849 -0.24267738030617136 APTAALPQGVVMAAS(ph)PGSLHSPQQLAEEATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APTAALPQGVVMAASPGSLHSPQQLAEEATR 31 0 E9PAR2;Q03060-22;Q03060-15;Q03060-16;Q03060-31;Q03060-20;Q03060-21;Q03060-32;Q03060-26;Q03060-29;Q03060-7;Q03060-12;G5E998;C9IYM9;C9K092;J3KR46;Q03060;Q03060-6;Q03060-2;Q03060-23;Q03060-9;Q03060-11;Q03060-24;Q03060-27;Q03060-8;E9PB41;Q03060-10;Q03060-28;Q03060-19;Q03060-14;Q03060-13;Q03060-17;Q03060-30;Q03060-1 E9PAR2 CREM cAMP-responsive element modulator 1 APTAALPQGVVMAAS(0.805)PGS(0.194)LHS(0.001)PQQLAEEATR 99.09299999999999 8.949100000000001e-13 5786300.0 10906.0 16329.0 25707.0 30767.0 32064.0 29956.0 26663.0 24757.0 26501.0 17637.0 True False 12752.170396681382 17950.035205398515 26319.952374340417 29043.224737959823 25781.2893733499 28385.054625475892 24137.28761659665 24107.15498220976 26888.526990033646 20834.448485584813 0.6120714165054336 0.8615555731085467 1.2632900934503248 1.3940001703455023 1.2374356533213617 1.3624096958993315 1.1585277927225694 1.1570815036879571 1.2905802142368972 1.0 14.346683290118213 -5.077031118319641 2.816489761760969 1.2471671270224898 0.6263150371980836 0.7810417074695116 0.10847780933455102 0.12032015273448526 1.750450839845137 0.028427266341687303 0.12347451886191158 8.374692731438182e-06 5.077031118319641 -0.6208520898244062 APTVPPPLPPT(ph)PPQPAR ddPTM_PC-9_AZD4547_30min_R2 4 APTVPPPLPPTPPQPAR 17 0 Q9Y3L3;A0A2R8Y5V0 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 APTVPPPLPPT(1)PPQPAR;APTVPPPLPPT(1)PPQPAR;APTVPPPLPPT(1)PPQPAR;APTVPPPLPPT(1)PPQPAR 135.55 9.125199999999999e-08 18039000.0 48596.7 56482.7 103513.0 108785.0 109265.0 112342.0 102300.0 128927.0 96248.0 105784.0 True False 64049.439725845965 74739.6281956008 102140.34998580732 83706.29896149568 94095.4408011879 105317.23698064238 111404.5018186403 109004.29459772652 101335.47278581365 102080.53435814386 0.627440286520563 0.7321633714551393 1.0005859650719853 0.8200025547262203 0.9217765305876955 1.0317073440382152 1.0913393284931663 1.0678264498037504 0.9927012375374504 1.0 16.63934826070774 -4.135273307664686 0.49169952131959815 1.0447732925154296 1.488067600552691e-17 0.7844367927409475 0.06760333878502396 3.8691433266823925 0.4469017055244052 0.04343518345694213 2.6705424085188927 7.323635013695537e-05 4.135273307664686 -1.0447732925154296 APTVPPPLPPT(ph)PPQPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 APTVPPPLPPTPPQPAR 17 0 Q9Y3L3;A0A2R8Y5V0 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 APTVPPPLPPT(1)PPQPAR;APTVPPPLPPT(1)PPQPAR;APT(0.046)VPPPLPPT(0.954)PPQPAR 147.75 0.00019174 16845700.0 53754.0 67286.0 102295.0 93603.0 117827.0 92511.0 93403.0 70586.0 70665.0 61086.0 True False 62853.49051010559 73965.70940231749 104734.10075594805 88358.72737502026 94739.64517819657 87659.56030369218 84555.1916608399 68733.1922920492 71698.34193995438 72160.40824349002 0.8710245970064332 1.0250178900420832 1.451406710485132 1.2244765450449289 1.3129033979203346 1.214787477475232 1.1717670911107696 0.9525055908791924 0.9935966783616786 1.0 16.13891988013266 -7.720363454664656 6.108389161362151 0.9795386599145091 1.1950926005745688 0.2760820457339631 0.14713124395562946 0.24568329639852718 23.1682280324934 0.07760260770677295 0.043049518280161216 1.9038667329966653e-08 7.720363454664656 0.21555394066005973 APTVPPPLPPT(ph)PPQPAR ddPTM_PC-9_Lapatinib_30min_R1 3 APTVPPPLPPTPPQPAR 17 0 Q9Y3L3;A0A2R8Y5V0 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 APTVPPPLPPT(1)PPQPAR;APTVPPPLPPT(1)PPQPAR;APTVPPPLPPT(1)PPQPAR 140.75 8.3679e-05 17257400.0 151220.0 211814.0 218032.0 202244.0 185386.0 179873.0 175276.0 170942.0 180020.0 132753.0 True False 149063.5750696483 211323.55769681322 200106.25058785867 217117.69842620642 174481.95996289916 172180.25109444276 184350.93364794532 178884.5893744516 159744.2519053603 155699.17916774668 0.9573818941527666 1.3572554385090119 1.2852106970472132 1.3944691268557612 1.1206350662575835 1.1058520155006069 1.1840199455986207 1.1489115763527917 1.0259800517847018 1.0 17.248401813113603 -6.4346530809046705 11.99176167994013 1.108536946048702 1.2589388986006973 0.26954994506643914 0.12066175103391318 1.1953411848236521 159.33461691977902 0.03690464102561276 0.04184045044488005 3.675758067557403e-07 6.4346530809046705 0.1504019525519953 APTVPPPLPPT(ph)PPQPARR ddPTM_PC-9_AZD4547_30min_R2 2 APTVPPPLPPTPPQPARR 18 1 Q9Y3L3;A0A2R8Y5V0 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 APTVPPPLPPT(1)PPQPARR;APTVPPPLPPT(1)PPQPARR 97.689 0.00064284 28900000.0 106139.0 112731.0 147593.0 200633.0 184556.0 149887.0 135435.0 167255.0 144340.0 168576.0 True False 139888.99417165312 149169.09117514335 145635.82038444706 154380.1615989501 158933.58506844897 140514.542195417 147488.45262763952 141409.5828875471 151969.5177240497 162674.20555054097 0.8599334706951511 0.9169806034724926 0.8952606831031962 0.9490143878464247 0.977005447978476 0.8637788745909122 0.9066492879340763 0.8692809189322446 0.9341955426168322 1.0 17.31162598251828 -12.955333148021584 0.9659682317812899 3.2105284084522507 0.9086383133764518 0.3668967000415908 0.03624986894260045 48231.49815618601 590.8915027440156 232840.9115718771 0.01149398758939716 1.1083242916719617e-13 12.955333148021584 -2.301890095075799 APTVPPPLPPT(ph)PPQPARR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APTVPPPLPPTPPQPARR 18 1 Q9Y3L3;A0A2R8Y5V0 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 APTVPPPLPPT(1)PPQPARR 84.324 0.0016614000000000002 11797000.0 96231.0 95358.0 85733.0 123880.0 131660.0 108910.0 128900.0 119240.0 102510.0 106110.0 True False 112521.00765111353 104824.51204093275 87777.19986421296 116939.40522437905 105862.16812921816 103198.56787490258 116689.65884481513 116110.07634522309 104009.01482013335 125346.90303370192 0.8976768067485488 0.8362752449715385 0.7002741810111764 0.9329261624671943 0.8445535196091369 0.8233036906157599 0.9309337209028681 0.9263098930653649 0.8297693225988083 1.0 16.935566826148232 -10.222127579032183 0.19977647249527206 1.1000173001774969 0.8091245222767759 0.313426748379419 0.06569041742668309 19.131326018978264 0.9757013409319604 1.333049356657262 0.21146465734415823 5.996149065598796e-11 10.222127579032183 -0.290892777900721 APTVPPPLPPT(ph)PPQPARR ddPTM_PC-9_Lapatinib_30min_R1 2 APTVPPPLPPTPPQPARR 18 1 Q9Y3L3;A0A2R8Y5V0 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 APTVPPPLPPT(1)PPQPARR;APTVPPPLPPT(1)PPQPARR 85.805 0.0015344000000000002 18078600.0 69756.0 39492.0 44928.0 41843.0 33358.0 40997.0 34313.0 38626.0 43470.0 27843.0 True False 68761.2666483162 39400.558700381254 41234.1932670953 44920.2738041561 31395.948024351324 39243.65387867477 36089.55924520155 40420.70497114566 38573.950840606616 32655.625451534557 2.1056484356843015 1.2065473606946253 1.2626980098204679 1.3755753620711988 0.9614254080341298 1.2017425278507605 1.1051559645906468 1.2377868870138637 1.1812344827954886 1.0 14.995043919926138 -4.760726981143969 6.069160112116877 1.1773086456553417 2.1391487125821858 0.854525408816927 0.11581441597290659 0.04659223828261098 6.7833323612625005 0.0284212423251996 0.18624521163350152 1.734894294831389e-05 4.760726981143969 0.9618400669268441 APVDEDRLS(ph)PLVAADSLLEHVR ddPTM_PC-9_AZD4547_30min_R2 1 APVDEDRLSPLVAADSLLEHVR 22 1 Q01094 Q01094 E2F1 Transcription factor E2F1 1 APVDEDRLS(0.998)PLVAADS(0.002)LLEHVR 45.424 0.027583 2307300.0 4292.8 3959.4 7595.3 11854.0 8836.5 5958.8 6081.3 7444.0 5727.7 6740.4 True False 5657.821104213072 5239.198619712969 7494.58135931914 9121.243442474342 7609.704504092794 5586.195294015156 6622.523918960878 6293.700846102656 6030.454528668694 6504.420647618083 0.8698424365104622 0.8054827483569289 1.1522288863749384 1.4023145083358868 1.1699281021868513 0.8588305702615987 1.018157385221702 0.967603601776187 0.9271316932549626 1.0 12.667204845674169 -6.757641211093445 24.986617289032516 0.95630817531345 1.0866342228118162 0.13410015621175353 0.15910829411656657 236.76317147937638 1557569.2148024598 0.061337670006823254 0.0591308899737733 1.7472650458393467e-07 6.757641211093445 0.13032604749836618 APVGSVVS(ph)VPSQSSASSDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APVGSVVSVPSQSSASSDK 19 0 P52594-2;P52594-3;P52594;P52594-4 P52594-2 AGFG1 Arf-GAP domain and FG repeat-containing protein 1 1 APVGS(0.002)VVS(0.677)VPS(0.28)QS(0.03)S(0.01)ASSDK 77.795 0.0033013000000000005 3388400.0 11804.0 19513.0 11662.0 8890.8 12825.0 6148.4 6039.3 6446.5 4239.2 4927.0 True False 13802.184060372918 21450.12168307558 11940.066308381292 8392.677300362506 10312.033315032828 5825.967080360394 5467.2137832544 6277.286205631344 4301.1902802215245 5820.226097889457 2.371417162879273 3.6854447442950486 2.051478088232865 1.4419847544077156 1.7717582000417818 1.000986384785467 0.9393473193828213 1.0785296138078944 0.7390074213407674 1.0 12.506859483150981 -5.740665255197538 1.0833751634916438 0.9933068020481154 3.137478524569359 0.7734131847348353 0.40865917627112913 0.2590324587834389 0.5790037023135458 0.1492751538114861 0.4393427294204041 1.8169155624534386e-06 5.740665255197538 2.1441717225212433 APVGSVVS(ph)VPSQSSASSDK ddPTM_PC-9_Lapatinib_30min_R1 1 APVGSVVSVPSQSSASSDK 19 0 P52594-2;P52594-3;P52594;P52594-4 P52594-2 AGFG1 Arf-GAP domain and FG repeat-containing protein 1 1 APVGS(0.001)VVS(0.977)VPS(0.021)QS(0.001)SASSDK 190.23 2.2923e-47 0.0 5855.5 13921.0 10188.0 10295.0 11183.0 10853.0 13836.0 15520.0 10349.0 17513.0 True False 5771.999496232814 13888.766779803684 9350.381966817282 11052.128643113234 10525.237926623928 10388.842489578674 14552.360379932054 16241.115858545558 9183.386640198705 20540.098715394328 0.2810112831593567 0.676178190389824 0.45522575603832843 0.5380757315849665 0.5124239212509483 0.5057834742436013 0.7084854158478506 0.7907029115869447 0.447095545520235 1.0 14.326155494792102 -14.522878743366805 0.11806390595481556 2.4471633503541446 0.3343263716564495 0.5588768915708708 0.12941812688388601 116.19061794109159 0.8904918182504723 40.1524741951223 1.2668823388455968 3.000000013218215e-15 14.522878743366805 -2.112836978697695 APVHFVEPLS(ph)PTGVAGHR ddPTM_PC-9_AZD4547_30min_R2 2 APVHFVEPLSPTGVAGHR 18 0 Q5T5Y3-2;Q5T5Y3;Q5T5Y3-3 Q5T5Y3-2 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1 1 APVHFVEPLS(0.799)PT(0.201)GVAGHR;APVHFVEPLS(0.794)PT(0.206)GVAGHR 106.39 0.00018149 23300100.0 52613.0 61098.0 66615.0 87201.0 76672.0 79467.0 75626.0 92861.0 62279.0 68026.0 True False 69342.83958161631 80846.73366349025 65731.64157453227 67098.15669201993 66027.4162550561 74497.91592761995 82356.56749302524 78511.46618349545 65570.94079490169 65644.43044550299 1.0563400293218124 1.2315855757269152 1.001328538132442 1.0221454621001518 1.0058342468196302 1.1348703221588157 1.2545857574527426 1.1960110804628654 0.9988804891732237 1.0 16.002384991436656 -6.880843188221293 11.417507816132197 1.1381009518151566 1.0670760928451548 0.04949998724281235 0.09625382286972275 0.930014343531195 88.24670098990762 0.03490790571646961 0.030789437215450945 1.3156998094086221e-07 6.880843188221293 -0.07102485897000177 APVHFVEPLS(ph)PTGVAGHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APVHFVEPLSPTGVAGHR 18 0 Q5T5Y3-2;Q5T5Y3;Q5T5Y3-3 Q5T5Y3-2 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1 1 APVHFVEPLS(0.945)PT(0.055)GVAGHR;APVHFVEPLS(0.87)PT(0.13)GVAGHR 123.83 2.5661e-05 16263500.0 41415.0 48995.0 44148.0 48885.0 71512.0 57061.0 72881.0 67171.0 69205.0 50554.0 True False 48425.7415164643 53858.89980332541 45200.65575222237 46146.13193730835 57499.73695318738 54068.62070985042 65977.18406725352 65407.83242355752 70216.99220200282 59719.04001475619 0.8108928325790001 0.9018714934134444 0.7568885189891461 0.7727205917226054 0.962837596501544 0.9053832864106726 1.1047931120619316 1.0952592742179992 1.1757890311808872 1.0 15.865903353845042 -6.967132095446374 1.3485943439515429 1.1096148140321211 0.8194612753824441 0.7663444955793786 0.0668159001746129 0.19568382657881925 0.729247927818039 0.03469086658021012 0.026084831258871146 1.0786185986134624e-07 6.967132095446374 -0.2901535386496771 APVHFVEPLS(ph)PTGVAGHR ddPTM_PC-9_Lapatinib_30min_R1 2 APVHFVEPLSPTGVAGHR 18 0 Q5T5Y3-2;Q5T5Y3;Q5T5Y3-3 Q5T5Y3-2 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1 1 APVHFVEPLS(0.983)PT(0.017)GVAGHR;APVHFVEPLS(0.742)PT(0.258)GVAGHR 69.081 0.006433400000000001 18550700.0 47580.0 58438.0 56673.0 56641.0 64471.0 74238.0 64039.0 61039.0 79842.0 49514.0 True False 46901.50047489663 58302.69040142002 52013.564704106386 60806.56808883702 60678.942534862836 71063.01379723045 67354.62607476654 63875.0947738249 70849.3531864669 58072.42892674213 0.8076380020898122 1.003965073941859 0.8956671120080244 1.0470815361545145 1.044883839995892 1.2236962550141621 1.159838279878629 1.0999211838444503 1.2200170458832151 1.0 15.825565756749713 -6.024352539161669 1.3180746565822843 1.1458572744937456 0.8968305189850131 0.619955054419218 0.07818434279471918 0.27754906099372206 0.978683530496091 0.027208927100995622 0.04899623594645854 9.454693636805455e-07 6.024352539161669 -0.24902675550873254 APVPAPGLRPEEAPGLPAAPPPAPAAPAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 APVPAPGLRPEEAPGLPAAPPPAPAAPASPR 31 1 Q9C009 Q9C009 FOXQ1 Forkhead box protein Q1 1 APVPAPGLRPEEAPGLPAAPPPAPAAPAS(1)PR;APVPAPGLRPEEAPGLPAAPPPAPAAPAS(1)PR 123.19 4.3381e-18 13518200.0 7129.8 3458.2 13712.2 17075.0 15314.900000000001 12691.8 12240.099999999999 13056.1 13539.5 16899.7 True False 9396.928090947255 4575.99552121316 13530.367268607684 13138.622556120241 13188.69048941671 11898.179739642466 13329.44518778435 11038.579744331131 14255.170328562917 16308.046646868352 0.5762142023766994 0.2805974020249625 0.8296743050588423 0.8056527455814742 0.8087228823293404 0.7295895086201071 0.817353879125923 0.6768793334578105 0.8741188100109065 1.0 13.993296368120225 -5.273044730671537 24.99632415479518 0.8022918967925589 0.4284058029385199 0.6863068760853944 0.10487398857968733 334.59983268804126 720682.2565922161 0.02519635343872688 0.05315869106092511 5.332799668608364e-06 5.273044730671537 -0.373886093854039 APVPAPGLRPEEAPGLPAAPPPAPAAPAS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APVPAPGLRPEEAPGLPAAPPPAPAAPASPR 31 1 Q9C009 Q9C009 FOXQ1 Forkhead box protein Q1 1 APVPAPGLRPEEAPGLPAAPPPAPAAPAS(1)PR;APVPAPGLRPEEAPGLPAAPPPAPAAPAS(1)PR 125.95 2.6189e-16 16269600.0 18798.2 22143.9 26015.0 25241.0 29635.0 26811.0 32587.0 26649.0 26976.0 18992.1 True False 21980.363978626072 24342.20004806322 26635.2962624369 23826.82860242611 23828.234486627513 25404.983961931957 29500.123450550753 25949.49198694946 27370.47296642195 22435.217388619123 0.9797259192048753 1.084999517785438 1.18720918995634 1.0620279799255665 1.0620906440922224 1.132370750943529 1.3149025008117592 1.1566409871344971 1.219978059152053 1.0 14.453477542790955 -7.003292388719845 22.968516781547038 1.191319916606923 1.0828428432041068 0.2053661858754302 0.08734636843564236 65.1998147073759 454859.5894613636 0.03023367201427429 0.026064702857565677 9.924476581551134e-08 7.003292388719845 -0.1084770734028162 APVPASELLASGVLSR ddPTM_PC-9_Lapatinib_30min_R1 1 APVPASELLASGVLSR 16 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 130.56 6.1418e-05 3802900.0 1741.2 1636.4 1345.7 1828.8 2018.5 4017.1 1704.1 1527.6 2181.8 1730.3 False True 1716.370168703027 1632.6110163401158 1235.06174055222 1963.2960526979593 1899.775798523687 3845.2979973174683 1792.3299597746613 1598.5778727779757 1936.062708627457 2029.3800495201756 0.8457608367189988 0.8044875659076912 0.6085906584349425 0.9674363622339536 0.936136037689376 1.8948141321418068 0.8831908839344498 0.7877173490278184 0.9540168235541773 1.0 10.986823353903615 -6.075238142406738 2.882123480498854 1.0960442803277985 0.7614742209135031 0.18748821370332835 0.29509720588300636 0.4746344532208369 7.7200590883037385 0.09720858712723449 0.13718490810133893 8.409338948502998e-07 6.075238142406738 -0.3345700594142954 APVPEPGLDLSLS(ph)PRPDSPQPR ddPTM_PC-9_AZD4547_30min_R2 3 APVPEPGLDLSLSPRPDSPQPR 22 1 Q8TAP8 Q8TAP8 PPP1R35 Protein phosphatase 1 regulatory subunit 35 1 APVPEPGLDLS(0.211)LS(0.789)PRPDSPQPR;APVPEPGLDLS(0.192)LS(0.675)PRPDS(0.133)PQPR;APVPEPGLDLS(0.26)LS(0.738)PRPDS(0.002)PQPR 85.913 0.00010655 40236600.0 25458.7 25729.8 46463.1 70239.0 48219.3 47451.1 45157.7 56546.0 50073.3 50186.4 True False 33554.03702614366 34046.45467633752 45846.968935549754 54046.483731732376 41524.8825207041 44483.975215788836 49176.64781794346 47808.11499781314 52720.07241133196 48429.38941155128 0.6928445192856473 0.7030122636280197 0.94667658404577 1.1159852393026726 0.8574314693052824 0.9185326463186547 1.015429853968259 0.9871715414691982 1.088596677594231 1.0 15.563595193381408 -5.291247864721568 4.255240735912214 0.9911381796162998 0.6925529074724671 0.7386050118769492 0.07021075730684971 0.09910564779268397 4.2561711720057795 0.019083092968069308 0.04603338768112292 5.1138988688414645e-06 5.291247864721568 -0.2985852721438327 APVPEPGLDLSLSPRPDS(ph)PQPR ddPTM_PC-9_AZD4547_30min_R2 3 APVPEPGLDLSLSPRPDSPQPR 22 1 Q8TAP8 Q8TAP8 PPP1R35 Protein phosphatase 1 regulatory subunit 35 1 APVPEPGLDLS(0.001)LS(0.006)PRPDS(0.993)PQPR;APVPEPGLDLS(0.051)LS(0.014)PRPDS(0.935)PQPR;APVPEPGLDLSLSPRPDS(0.999)PQPR 103.75 2.2434000000000002e-05 51852700.0 41770.2 41721.8 65743.0 90829.0 76329.0 62574.0 56075.0 74909.0 53488.0 58853.0 True False 55052.254725866784 55207.555935732824 64871.20486428686 69889.77734406118 65732.03588444504 58661.2378881158 61065.566368330954 63333.53528757436 56315.26648208375 56792.57438345905 0.969356563309813 0.9720910970327863 1.1422480063376161 1.2306147080456475 1.1574054636197233 1.032903306901351 1.0752385682681154 1.1151728192483625 0.9915955931465169 1.0 15.793414689552588 -10.459959700552387 14.791752661092714 0.9999999999998005 1.0819280102112765 0.06798634057267272 0.08239714390770762 0.0 0.0 0.08713601211174866 0.021133587160696448 3.467690266658024e-11 10.459959700552387 0.081928010211476 APVPEPGLDLSLSPRPDS(ph)PQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 APVPEPGLDLSLSPRPDSPQPR 22 1 Q8TAP8 Q8TAP8 PPP1R35 Protein phosphatase 1 regulatory subunit 35 1 APVPEPGLDLS(0.031)LS(0.037)PRPDS(0.931)PQPR;APVPEPGLDLSLSPRPDS(1)PQPR;APVPEPGLDLS(0.173)LS(0.173)PRPDS(0.654)PQPR;APVPEPGLDLS(0.033)LS(0.178)PRPDS(0.789)PQPR;APVPEPGLDLS(0.011)LS(0.04)PRPDS(0.95)PQPR;APVPEPGLDLS(0.001)LS(0.013)PRPDS(0.986)PQPR 110.77 7.18e-06 82021900.0 48661.7 55698.7 58995.2 57420.3 72662.2 56755.700000000004 61221.0 60777.299999999996 52982.1 47851.7 True False 56899.16469761513 61228.09883611551 60401.869308541915 54203.226750124304 58424.5635199671 53779.33117930035 55421.70367834311 59181.96027387234 53756.86298021442 56526.83441615125 1.006586788121245 1.0831687192202113 1.068552129840893 0.9588937238388316 1.0335721807778009 0.9513947089868195 0.9804494493770489 1.0469710693185827 0.9509972305269341 1.0 15.78664828581226 -5.750871148307004 24.96984962167548 0.9908009363158462 1.0558091781989645 0.4020025246639489 0.03558830151292031 199.95399307405256 472431.5133411725 0.009306127219861772 0.015905365250453055 1.7747159467886967e-06 5.750871148307004 0.06500824188311827 APVPEPGLDLSLSPRPDS(ph)PQPR ddPTM_PC-9_Lapatinib_30min_R1 3 APVPEPGLDLSLSPRPDSPQPR 22 1 Q8TAP8 Q8TAP8 PPP1R35 Protein phosphatase 1 regulatory subunit 35 1 APVPEPGLDLS(0.006)LS(0.085)PRPDS(0.909)PQPR;APVPEPGLDLS(0.006)LS(0.004)PRPDS(0.99)PQPR;APVPEPGLDLSLS(0.05)PRPDS(0.95)PQPR 106.57 1.6245e-05 72846600.0 115814.0 94994.0 101553.0 91592.0 81535.0 82221.0 76530.0 70252.4 87063.0 72789.8 True False 114162.4711223134 94774.04722941379 93203.70434591647 98327.98122195517 76739.27160397757 78704.59949651241 80492.34893583419 73516.58297299537 77257.04812596586 85371.4199436881 1.3372446094678545 1.1101378809433855 1.0917436351345056 1.1517669647150457 0.898887141090023 0.9219080524656472 0.9428488947346524 0.8611381071263391 0.9049521277369572 1.0 16.381465554705834 -4.726241519830782 0.5164172080741254 0.9013449573491888 1.5900598104535637 0.7805986691695013 0.06630042825301992 2.1055391665379237 0.41311174711027937 0.040908966038050526 0.8935407319733109 1.878271981760223e-05 4.726241519830782 0.6887148531043749 APVPGT(ph)PDSLSSGSSR ddPTM_PC-9_AZD4547_30min_R2 4 APVPGTPDSLSSGSSR 16 0 Q9UJZ1;Q9UJZ1-2;A0A087WYB4 Q9UJZ1 STOML2 Stomatin-like protein 2, mitochondrial 1 APVPGT(0.993)PDS(0.007)LSSGSSR;APVPGT(1)PDSLSSGSSR;APVPGT(0.961)PDS(0.034)LS(0.002)S(0.002)GS(0.001)SR;APVPGT(0.966)PDS(0.02)LS(0.007)S(0.002)GS(0.003)S(0.002)R 186.42 1.4171e-07 58124000.0 98121.0 101761.0 128342.0 172360.0 152769.0 141918.0 92028.0 152675.0 101967.0 126237.0 True False 129321.43695641325 134653.25320518547 126640.1012228269 132625.0649354543 131559.66133488953 133043.84502518014 100218.31371814103 129082.58687247756 107356.76745024385 121817.4810535524 1.0615999923653159 1.1053688849959908 1.0395889007683095 1.0887194825277233 1.079973581764134 1.0921572493088452 0.8226923825003726 1.0596392714419316 0.88129196665172 1.0 16.89436165217724 -7.220664829059031 24.983008084365633 0.9458757754648267 1.0779943524969187 0.5416658387325155 0.06166801924197545 369.6354516424455 226479.8962964482 0.02155131058027669 0.016693368431940574 6.016378781733126e-08 7.220664829059031 0.13211857703209196 APVPGT(ph)PDSLSSGSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 APVPGTPDSLSSGSSR 16 0 Q9UJZ1;Q9UJZ1-2;A0A087WYB4 Q9UJZ1 STOML2 Stomatin-like protein 2, mitochondrial 1 APVPGT(0.999)PDS(0.001)LSSGSSR;APVPGT(0.99)PDS(0.01)LSSGSSR;APVPGT(0.994)PDS(0.004)LS(0.001)S(0.001)GSSR;APVPGT(0.998)PDS(0.002)LSSGSSR;APVPGT(0.959)PDS(0.017)LS(0.017)S(0.005)GS(0.002)S(0.001)R 160.63 7.2908e-05 45268000.0 84177.0 86314.3 100831.0 96701.1 119625.0 96325.0 85348.0 85288.3 80999.9 66836.7 True False 98426.5035284657 94883.01327266375 103235.19344369696 91283.25087619617 96185.33998524758 91273.54742952876 77263.2195739898 83049.57249542374 82184.3703007445 78953.66463097393 1.2466362896327485 1.2017556590456304 1.3075415045801086 1.1561623048512086 1.2182504819100388 1.1560394043283162 0.978589403482597 1.0518773622933641 1.040919008444646 1.0 16.26871860981779 -7.0635610552014905 3.264737705545549 1.022467059298944 1.224547239997888 0.8507631224770801 0.04105725489293837 0.09457108423653568 1.981325802726158 0.01647938669298009 0.01285204262610647 8.638512078008614e-08 7.0635610552014905 0.20208018069894407 APVPGT(ph)PDSLSSGSSR ddPTM_PC-9_Lapatinib_30min_R1 4 APVPGTPDSLSSGSSR 16 0 Q9UJZ1;Q9UJZ1-2;A0A087WYB4 Q9UJZ1 STOML2 Stomatin-like protein 2, mitochondrial 1 APVPGT(0.986)PDS(0.014)LSSGSSR;APVPGT(0.999)PDS(0.001)LSSGSSR;APVPGT(0.996)PDS(0.003)LSSGSSR;APVPGT(0.448)PDS(0.248)LS(0.248)S(0.052)GS(0.003)S(0.001)R 194.67 2.2423999999999997e-11 36235300.0 126612.0 113009.0 103983.0 91519.0 107299.0 88956.0 82172.0 72482.0 113871.0 81994.0 True False 124806.48966220293 112747.33460375205 95433.91912598739 98249.61255843424 100987.88377795041 85151.55924656425 86426.46408931617 75849.77832855028 101045.64886521084 96166.55364986252 1.297815975776952 1.1724173355973566 0.9923816077828617 1.0216609499822156 1.0501352075654298 0.8854591956845694 0.8987164539969945 0.7887334572133616 1.050735885088623 1.0 16.55324759710414 -3.847218078819042 0.5672241185461251 0.919014468377092 2.2302533370071287 0.690566969958806 0.07658533364800207 5.53427927777307 0.6093891051796896 0.03857782514501213 6.038550174291387 0.00014216147510700454 3.847218078819042 1.3112388686300367 APVPSTCSSTFPEELS(ph)PPSHQAK ddPTM_PC-9_AZD4547_30min_R2 4 APVPSTCSSTFPEELSPPSHQAK 23 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;Q14980-4;Q14980-3;F5H6Y5;F5H4J1;F5H0Z7;F5H763 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 APVPSTCSSTFPEELS(0.998)PPS(0.002)HQAK;APVPSTCSSTFPEELS(0.998)PPS(0.002)HQAK;APVPSTCSSTFPEELS(0.998)PPS(0.002)HQAK;APVPSTCSSTFPEELS(0.994)PPS(0.006)HQAK 127.16 2.2085e-07 911030000.0 1043943.0 938370.0 1270900.0 1706530.0 1598010.0 1469230.0 1187949.0 1466290.0 1050900.0 1384380.0 True False 1375895.1586366706 1241679.7516745122 1254047.0356086916 1313115.8741256734 1376153.8951604527 1377358.8158397484 1293674.159637847 1239708.5724921923 1106448.4285451274 1335913.2775724763 1.029928500401498 0.9294613449241268 0.9387188949027095 0.9829349675390392 1.030122178036211 1.03102412331928 0.9683818413636975 0.9279858156248734 0.8282337237905775 1.0 20.3493949258809 -7.775116003113018 3.542294642319508 0.904868785761766 0.9872571058980564 0.2719412630020571 0.05146138302524573 0.284105440914403 7.482504184971793 0.03007980037321831 0.014255246645191125 1.678355657635381e-08 7.775116003113018 0.08238832013629038 APVPSTCSSTFPEELS(ph)PPSHQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 APVPSTCSSTFPEELSPPSHQAK 23 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;Q14980-4;Q14980-3;F5H6Y5;F5H4J1;F5H0Z7;F5H763 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 APVPS(0.003)T(0.001)CS(0.006)S(0.006)T(0.003)FPEELS(0.774)PPS(0.206)HQAK;APVPSTCSSTFPEELS(0.998)PPS(0.002)HQAK;APVPSTCSSTFPEELS(1)PPSHQAK;APVPSTCSSTFPEELS(0.798)PPS(0.202)HQAK;APVPSTCSSTFPEELS(0.959)PPS(0.041)HQAK 142.4 6.2628e-07 712614300.0 723005.0 706769.0 784220.0 871174.0 975850.0 810427.0 858610.0 775323.0 822483.0 625794.0 True False 845395.4665003332 776932.3554464015 802918.7789709134 822364.9451642167 784639.1976978404 767926.7814448043 777276.245001915 754971.5927726214 834510.2578900367 739245.4984174207 1.143592309063983 1.0509801643833625 1.0861327944367665 1.1124382183249522 1.0614054456572257 1.0387980489415014 1.0514453543050457 1.0212731689119072 1.1288675543869515 1.0 19.495694027620914 -6.433984214123935 5.3444761183962655 1.0496244524174234 1.0938044846120252 0.2791112147089173 0.03794005359467924 0.33225239078000524 15.270211433029315 0.01144527181045242 0.012908785856252547 3.6814235475652576e-07 6.433984214123935 0.04418003219460176 APVPSTCSSTFPEELS(ph)PPSHQAK ddPTM_PC-9_Lapatinib_30min_R1 5 APVPSTCSSTFPEELSPPSHQAK 23 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;Q14980-4;Q14980-3;F5H6Y5;F5H4J1;F5H0Z7;F5H763 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 APVPSTCSSTFPEELS(1)PPSHQAK;APVPS(0.002)T(0.001)CS(0.001)S(0.001)TFPEELS(0.989)PPS(0.005)HQAK;APVPSTCSSTFPEELS(0.953)PPS(0.047)HQAK;APVPSTCSSTFPEELS(0.999)PPSHQAK;APVPS(0.084)T(0.027)CS(0.009)S(0.009)T(0.009)FPEELS(0.706)PPS(0.157)HQAK 134.4 8.4669e-09 889060000.0 999007.3 944430.0 1208014.6 1059673.2 1131808.4 1124817.6 1006243.4 1024188.7 1144501.2 900806.1 True False 984761.2727065004 942243.2303606082 1108696.3026592066 1137605.1020941657 1065237.6551329293 1076711.773325893 1058341.7596652303 1071776.2459866737 1015595.422724068 1056509.2341363202 0.9320896030894869 0.8918457121966163 1.049395752385968 1.07675831439764 1.0082615662169243 1.019121971239644 1.0017345097134036 1.0144504291652823 0.961274534958799 1.0 20.010873946142183 -5.257852572734915 24.997972582467437 1.018332787348587 0.911967649768686 0.6549478207962283 0.030286303133110655 185.19374938321062 1290678.8805639746 0.008217756428459445 0.020105034734843884 5.522648814119354e-06 5.257852572734915 -0.10636513757990096 APVPSTCSSTFPEELSPPS(ph)HQAK ddPTM_PC-9_AZD4547_30min_R2 1 APVPSTCSSTFPEELSPPSHQAK 23 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;Q14980-4;Q14980-3;F5H6Y5;F5H4J1;F5H0Z7;F5H763 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 APVPSTCSSTFPEELS(0.42)PPS(0.579)HQAK 53.909 0.006758199999999999 4331900.0 8885.5 10328.0 11010.0 15669.0 17267.0 14543.0 9619.2 11281.0 10944.0 10727.0 True False 11710.904170118632 13666.324024952151 10864.000206193794 12056.754133636776 14869.775100115452 13633.623910999253 10475.290165140425 9537.780661591089 11522.47749738118 10351.450995044688 1.1313297213815459 1.3202326931262405 1.0495147213076184 1.1647404928457303 1.4364918606322647 1.3170737046937442 1.0119634600168632 0.9213955286226917 1.113126797672816 1.0 13.337545388494654 -7.2759236738949795 23.355576030829372 1.0050710004424515 1.2376876915514785 0.4955585578719097 0.11110002750034868 304.34449658430816 490744.76798861235 0.048851589829924755 0.03313790579549076 5.297565390195466e-08 7.2759236738949795 0.23261669110902705 APVPTGEVYFADSFDR ddPTM_PC-9_AZD4547_30min_R2 1 APVPTGEVYFADSFDR 16 0 P27824;P27824-2;D6RHJ3;D6RD16;D6RAQ8;D6RAU8;D6RB85;D6RDP7;H0Y9Q7 P27824 CANX Calnexin 0 107.97 0.0065826999999999995 0.0 1094.4 927.17 3558.9 4654.4 3565.9 1435.1 1250.2 3468.4 2023.1 1778.1 False True 1442.3964350658755 1226.8595707024485 3511.7066606560484 3581.3999897631643 3070.836336914445 1345.3629701351194 1361.4653780416832 2932.4384759030695 2130.036935759491 1715.8492602115175 0.8406312072472306 0.7150159394253608 2.0466288863994677 2.0872462825328113 1.7896888777606808 0.7840799313392325 0.7934644433007195 1.709030358262112 1.2413893138240566 1.0 10.74470710026317 -6.754822416007554 24.9996473556874 1.1303991806463605 1.5159179928970425 0.13641328989034696 0.4876552343457484 387.67546687346885 1464681.534866523 0.1833768428340049 0.1793181192501516 1.758642579869754e-07 6.754822416007554 0.3855188122506821 APVPTGEVYFADSFDR ddPTM_PC-9_Lapatinib_30min_R1 1 APVPTGEVYFADSFDR 16 0 P27824;P27824-2;D6RHJ3;D6RD16;D6RAQ8;D6RAU8;D6RB85;D6RDP7;H0Y9Q7 P27824 CANX Calnexin 0 161.48 0.00027258 2271700.0 3180.1 3260.2 3537.4 1864.9 1571.5 1278.1 1991.4 1216.4 2014.3 2073.9 False True 3134.7511908410843 3252.6512072060923 3246.5686267588794 2002.0509671240302 1479.0674596878753 1223.4386423966191 2094.5049480049647 1272.9183846865221 1787.428322480651 2432.3708517019545 1.2887636721380982 1.3372349059890187 1.334734226274428 0.823086235276654 0.6080764611419993 0.5029819534058989 0.8610960563597522 0.5233241402296234 0.7348502475393378 1.0 11.248147490878967 -5.834784513631704 3.789519327974204 0.681471484464451 1.3276575164953817 0.7884736492032042 0.1425541462777672 0.08830205198178522 2.4880588589569905 0.039020849209592604 0.0621548100043297 1.4629028512555823e-06 5.834784513631704 0.6461860320309306 APVQPQQS(ph)PAAAPGGTDEKPSGK ddPTM_PC-9_AZD4547_30min_R2 4 APVQPQQSPAAAPGGTDEKPSGK 23 1 Q13200;C9JPC0;F8WBS8 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 1 APVQPQQS(1)PAAAPGGTDEKPSGK;APVQPQQS(1)PAAAPGGTDEKPSGK;APVQPQQS(1)PAAAPGGTDEKPSGK;APVQPQQS(1)PAAAPGGTDEKPSGK 138.78 1.5215999999999998e-07 346488000.0 215142.0 236459.0 248928.0 264054.0 243902.0 262210.0 231981.0 277942.0 239000.0 254411.0 True False 283552.6807684054 312889.74754223105 245627.05207333431 203180.4298936325 210040.41735497545 245813.967249062 252626.85959325486 234992.45037177094 251633.05207182976 245504.14832668193 1.1549812200773646 1.274478454538707 1.0005006178001068 0.8276048746160857 0.855547324909083 1.0012619702130972 1.0290125902764586 0.957183216550282 1.0249645628675583 1.0 17.905387876654046 -5.3561420397884785 5.166581372729731 0.95301224079121 1.2132210290655774 0.6793590353454317 0.06973601183323662 0.12154417203217044 5.073903748957399 0.019873472711350863 0.04292340187943126 4.40410799765743e-06 5.3561420397884785 0.26020878827436733 APVQPQQS(ph)PAAAPGGTDEKPSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 APVQPQQSPAAAPGGTDEKPSGK 23 1 Q13200;C9JPC0;F8WBS8 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 1 APVQPQQS(1)PAAAPGGTDEKPSGK;APVQPQQS(0.977)PAAAPGGT(0.021)DEKPS(0.002)GK;APVQPQQS(1)PAAAPGGTDEKPSGK;APVQPQQS(1)PAAAPGGTDEKPSGK;APVQPQQS(0.998)PAAAPGGTDEKPS(0.001)GK 128.58 4.8599e-09 327977600.0 287211.0 324105.0 317995.0 295945.0 334606.0 235804.0 328105.0 269563.0 244894.0 222047.0 True False 335830.1496241753 356280.00246467604 325577.20680275396 279364.1611166351 269042.35628926853 223438.0231307821 297024.5191255089 262487.256875607 248475.11145606957 262302.3633769146 1.2803169033654689 1.3582798030405872 1.2412286439635192 1.0650462981730882 1.0256955096613787 0.8518338159603751 1.1323745440246011 1.0007048868958406 0.9472850654381029 1.0 18.000871280960006 -5.761673428743592 2.194964849949438 0.9939089295723138 1.3213324491948844 0.8007112881123772 0.06781752144384932 0.12776716526105342 1.2558630137882985 0.02044705446952596 0.03895179523642736 1.7311175978268458e-06 5.761673428743592 0.32742351962257055 APVQPQQS(ph)PAAAPGGTDEKPSGK ddPTM_PC-9_Lapatinib_30min_R1 4 APVQPQQSPAAAPGGTDEKPSGK 23 1 Q13200;C9JPC0;F8WBS8 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 1 APVQPQQS(1)PAAAPGGTDEKPSGK;APVQPQQS(1)PAAAPGGTDEKPSGK;APVQPQQS(1)PAAAPGGTDEKPSGK;APVQPQQS(1)PAAAPGGTDEKPSGK 129.37 1.3808e-08 324218000.0 178955.0 253323.0 280141.0 256142.0 280677.0 281494.0 259257.0 259350.0 269874.0 214909.0 True False 176403.06888367241 252736.4461576183 257108.88835553214 274979.5371446641 264168.1306922138 269455.15781456354 272680.0589057568 271400.34780372324 239477.94822079325 252055.73430175768 0.6998573921452034 1.0027006402284253 1.020047764704789 1.0909473569661476 1.048054436944312 1.0690300641681714 1.081824461011103 1.0767473652426667 0.9500991869286081 1.0 17.943383250663096 -4.708538239050291 2.737996847224837 1.0486188653016948 0.5900186631665464 0.8580126036261562 0.041408477746131794 0.20769546768962915 1.740243117892836 0.010501606001664325 0.23627856589893287 1.9564185003097034e-05 4.708538239050291 -0.4586002021351484 APVS(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 2 APVSPLK 7 0 Q9UBS0 Q9UBS0 RPS6KB2 Ribosomal protein S6 kinase beta-2 1 APVS(1)PLK;APVS(1)PLK 83.78299999999999 0.020513 95061000.0 187257.0 183362.0 211330.0 245670.0 229580.0 199132.0 208060.0 215847.0 184851.0 222080.0 True False 246800.83081243632 242630.18066065802 208527.6261194311 189034.577063664 197706.77983926015 186680.24456062051 226576.93693437206 182492.80582062376 194621.84647920416 214305.046795891 1.151633311965327 1.1321720336887098 0.9730411356949403 0.882081779640518 0.9225484084262402 0.8710958857558732 1.057263654412064 0.8515562678019154 0.9081533514447117 1.0 17.709306299727388 -5.3107910564537235 3.176980013313052 0.9242038051595866 1.1498929989527396 0.6785506362174067 0.05814816284317159 0.1322024314849476 2.6522506877244147 0.015249738571188987 0.04029583956294118 4.888875115861037e-06 5.3107910564537235 0.225689193793153 APVS(ph)PLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APVSPLK 7 0 Q9UBS0 Q9UBS0 RPS6KB2 Ribosomal protein S6 kinase beta-2 1 APVS(1)PLK;APVS(1)PLK 81.97200000000001 0.023162000000000002 46045000.0 173857.0 180099.0 201710.0 239820.0 256260.0 232987.0 294000.0 251400.0 224380.0 192985.0 True False 203287.55626772798 197978.03848717388 206519.53138943535 226383.66290693037 206047.69257780234 220768.75156982717 266150.19162432646 244801.0163803176 227661.13301474456 227971.65283158064 0.8917229565287724 0.8684327021721194 0.9059000486433568 0.9930342658618901 0.9038303228429232 0.9684043995282398 1.1674705531084213 1.07382217630878 0.9986379016295264 1.0 17.79849491785391 -7.035843652077296 7.169342880934841 1.066840783408829 0.916156874413255 0.629181791132283 0.05324369747373641 0.1498877980264053 24.410565803111478 0.02082239743397553 0.01645379535101555 9.207809972991738e-08 7.035843652077296 -0.15068390899557393 APVSSTESVIQSNT(ph)PTPPPSQPLNETAEEESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APVSSTESVIQSNTPTPPPSQPLNETAEEESR 32 0 B5MBZ0;Q9HC35;Q9HC35-2 B5MBZ0 EML4 Echinoderm microtubule-associated protein-like 4 1 APVSSTES(0.001)VIQS(0.19)NT(0.455)PT(0.346)PPPS(0.008)QPLNETAEEESR 58.021 0.0021908 3188400.0 1638.8 1999.3 1861.5 3906.2 1236.7 3304.1 4471.5 1601.7 1484.6 1640.6 True False 1916.2164722245968 2197.7772910866106 1905.8852197780627 3687.3482780712675 994.3775127252318 3130.827179464377 4047.927149143453 1559.6570721414307 1506.309466412738 1938.0277930175455 0.9887456099073852 1.1340277466633388 0.983414802741587 1.9026292044707973 0.5130873335809945 1.6154707330536373 2.0886837452628866 0.8047650698099719 0.7772383202345029 1.0 10.920373545075076 APVSSTESVIQSNTPT(ph)PPPSQPLNETAEEESR ddPTM_PC-9_AZD4547_30min_R2 3 APVSSTESVIQSNTPTPPPSQPLNETAEEESR 32 0 B5MBZ0;Q9HC35;Q9HC35-2 B5MBZ0 EML4 Echinoderm microtubule-associated protein-like 4 1 APVSSTESVIQSNT(0.002)PT(0.996)PPPS(0.001)QPLNETAEEESR;APVSSTESVIQSNT(0.004)PT(0.99)PPPS(0.006)QPLNETAEEESR;APVSSTESVIQSNT(0.004)PT(0.995)PPPSQPLNETAEEESR 131.68 1.2422e-17 16171400.0 13140.100000000002 11363.0 15975.7 25233.199999999997 26588.7 15172.900000000001 17436.5 19670.6 14751.8 19639.3 True False 17318.37846894107 15035.867534424016 15763.851779663057 19416.075589053777 22897.317959369877 14224.136164422785 18988.314721023682 16630.960755420052 15531.550031603407 18951.734084737676 0.9138149781706789 0.7933768734404516 0.8317894135269709 1.024501267390093 1.208191179603437 0.7505453643884679 1.001930199955447 0.8775429562835306 0.8195318677519524 1.0 14.210042240663107 -5.739912203290316 24.86738071519954 0.9535390947472315 0.8410319945484356 0.14302120176489264 0.12123417253944106 456.12412983199505 526892.8832441363 0.033846146191350256 0.0585524430827694 1.8200687654211757e-06 5.739912203290316 -0.11250710019879595 APVSSTESVIQSNTPT(ph)PPPSQPLNETAEEESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 APVSSTESVIQSNTPTPPPSQPLNETAEEESR 32 0 B5MBZ0;Q9HC35;Q9HC35-2 B5MBZ0 EML4 Echinoderm microtubule-associated protein-like 4 1 APVSSTESVIQSNT(0.001)PT(0.991)PPPS(0.007)QPLNETAEEESR;APVSSTESVIQSNT(0.005)PT(0.992)PPPS(0.003)QPLNETAEEESR 130.77 1.5696e-15 10375900.0 13468.5 14918.1 18134.2 18374.1 20432.6 18470.4 15219.0 12504.300000000001 20405.0 12299.7 True False 15748.451034999383 16399.07037771177 18566.588102336467 17344.65874663593 16428.978706646376 17501.77970871912 13777.346143981711 12176.075374400996 20703.384522532604 14529.538245628379 1.0838920527799807 1.1286711319023435 1.2778512151219086 1.193751546223746 1.13072958196655 1.2045654454287302 0.9482301440740565 0.8380221840886452 1.4249168949854136 1.0 13.826701233839714 -7.244614956124615 24.49451899205484 1.039294147367707 1.1722448404362003 0.12596350771427522 0.1493788030402736 1192.700840818567 1736444.0739289124 0.05600666601924908 0.04326132007288927 5.693574973808812e-08 7.244614956124615 0.13295069306849316 APVSSTESVIQSNTPT(ph)PPPSQPLNETAEEESR ddPTM_PC-9_Lapatinib_30min_R1 2 APVSSTESVIQSNTPTPPPSQPLNETAEEESR 32 0 B5MBZ0;Q9HC35;Q9HC35-2 B5MBZ0 EML4 Echinoderm microtubule-associated protein-like 4 1 APVSSTESVIQS(0.001)NT(0.005)PT(0.988)PPPS(0.005)QPLNET(0.001)AEEESR;APVSSTESVIQSNT(0.001)PT(0.999)PPPSQPLNETAEEESR 125.95 1.5821e-16 10148500.0 22859.8 17448.3 22377.5 11568.2 18953.7 14900.9 18513.1 19112.4 25675.9 18424.0 True False 22533.8150600261 17407.89953337036 20537.708329647998 12418.964018383933 17838.880630407933 14263.623242694455 19471.617732705996 20000.431877246538 22784.009762786565 21608.563851563133 1.0428187275572243 0.8056018740047408 0.9504430035576996 0.5747241743456062 0.825546794916567 0.6600912184944973 0.9011065180667917 0.9255789516895513 1.0543972250677087 1.0 14.399315570530838 -7.803634500474468 2.218946763316974 1.0176854296732873 0.8063919739243046 0.3026482027567917 0.12623370707366477 0.39034200558542465 3.7725774667447314 0.08909788843989115 0.03628326024939084 1.5716849681533955e-08 7.803634500474468 -0.21129345574898273 APYS(ph)PTTSK ddPTM_PC-9_AZD4547_30min_R2 2 APYSPTTSK 9 0 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 APYS(0.877)PT(0.11)T(0.01)S(0.003)K;APYS(0.397)PT(0.256)T(0.256)S(0.091)K 122.69 0.0015411 50028000.0 93531.0 121770.0 150275.0 183391.0 186805.0 178099.0 170113.0 197288.0 141430.0 149478.0 True False 123271.91243434434 161129.7711578642 148282.25531205928 141113.03831270538 160870.35023901451 166962.44137557992 185252.72744745246 166801.67282723048 148905.7010649324 144244.82071756248 0.8546020011055787 1.117057585543145 1.0279901529525435 0.9782884238804714 1.11525910905325 1.1574934929726142 1.284293789724244 1.1563789396212378 1.0323122890942207 1.0 17.138159992550314 -6.375399583502533 4.3596138882714355 1.1448402559758817 1.0059163810654894 0.29697114874534825 0.09491278506662501 0.2861087533288657 8.96642199439861 0.030217410312411087 0.03445768864088036 4.2130868944763565e-07 6.375399583502533 -0.13892387491039226 APYS(ph)PTTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 APYSPTTSK 9 0 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 APYS(0.927)PT(0.062)T(0.008)S(0.002)K;APYS(0.585)PT(0.4)T(0.012)S(0.003)K;APY(0.002)S(0.546)PT(0.39)T(0.045)S(0.017)K 123.62 0.0014850999999999998 47253100.0 149833.0 162600.0 194665.0 188093.0 221299.0 173724.0 202802.0 179569.0 157473.0 145396.0 True False 175196.76756335646 178741.8534140367 199306.5518711238 177554.7590157339 177937.04955816362 164613.60761637634 183591.126400669 174855.5040190827 159775.74471535272 171755.14384589746 1.0200379659112098 1.0406783133925113 1.1604109630040897 1.0337667626131768 1.0359925506383245 0.9584202483278832 1.0689119538998555 1.0180510469949415 0.9302530400993817 1.0 17.38999378099018 -6.280780165475773 2.6315729533087686 1.001540273929886 1.071520993602216 0.29184680947482344 0.049634142097742695 0.3851518256668207 5.2920122967051 0.01662724330643828 0.02069771996880195 5.238655437769716e-07 6.280780165475773 0.0699807196723301 APYS(ph)PTTSK ddPTM_PC-9_Lapatinib_30min_R1 2 APYSPTTSK 9 0 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 APY(0.001)S(0.951)PT(0.026)T(0.017)S(0.005)K;APYS(0.994)PT(0.006)TSK 133.91 0.001145 50232000.0 198370.0 330010.0 370110.0 312050.0 324060.0 304900.0 298430.0 323650.0 307620.0 220244.0 True False 195541.20742339722 329245.88212075364 339680.98446591495 334999.1979682849 304999.4279264735 291860.13775661465 313881.2451707955 338687.9605424138 272972.5962177918 258312.88194331696 0.7569936348211466 1.2746010947800965 1.3149982374493157 1.2968737580876653 1.1807364217840333 1.1298706265088985 1.2151203718894368 1.3111539695365793 1.0567517739114989 1.0 17.978760066217646 -10.163023476868437 15.059122768416941 1.0000106645236058 1.1863133572453541 0.0855840041563124 0.1604093700226737 0.0 0.0 0.15172381254065642 0.03679842970744353 6.87031299824628e-11 10.163023476868437 0.18630269272174838 APYTCGGDSDQYVLMSS(ph)PVGR ddPTM_PC-9_AZD4547_30min_R2 2 APYTCGGDSDQYVLMSSPVGR 21 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 APYTCGGDSDQYVLMS(0.26)S(0.74)PVGR;APYTCGGDSDQYVLMS(0.241)S(0.759)PVGR 95.429 0.00030704 8227900.0 15948.5 17167.1 23500.2 32269.0 28773.0 24677.4 21704.9 24423.9 23322.0 25095.0 True False 21019.791250592214 22716.029354062357 23188.571993242094 24829.880601080193 24778.365608132397 23134.318276923143 23636.594052037217 20649.74746038778 24554.753307193347 24216.431688323522 0.8679970493228101 0.9380419727575051 0.9575552786508579 1.0253319283638496 1.0232046540564366 0.9553149107462374 0.9760560249441751 0.8527163591300078 1.0139707461125642 1.0 14.563698677908636 -4.797595122397719 1.994551884100474 0.9730088713960594 0.8397702878285911 0.32423095333222796 0.04758518654786402 0.9494169511265815 4.255561821168766 0.013400483771578976 0.2325784557163693 1.593693779853385e-05 4.797595122397719 -0.13323858356746832 APYTCGGDSDQYVLMSS(ph)PVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 APYTCGGDSDQYVLMSSPVGR 21 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 APYTCGGDSDQYVLMS(0.183)S(0.817)PVGR 91.589 0.000953 0.0 3885.8 2730.1 5132.5 5764.2 7414.2 6785.0 8776.0 7703.2 7555.0 5236.0 True False 4543.589191951637 3001.1262853976646 5254.878265114642 5441.250561788545 5961.440733280029 6429.1826556901415 7944.673747262205 7500.999162215063 7665.477582344225 6185.245351846807 0.7345851188578962 0.4852073142905447 0.8495828324005977 0.8797145872578656 0.963816371730516 1.039438581651494 1.2844557160355916 1.2127245946638794 1.239316655410516 1.0 12.594615108784039 -6.116358811235191 0.8378051643067407 1.1994880496457185 0.5973580837636377 0.7835882152772794 0.10901715047364714 0.28574986304296185 0.4172018560871169 0.05375450128296642 0.10863116982656434 7.649643372709983e-07 6.116358811235191 -0.6021299658820808 APYTCGGDSDQYVLMSS(ph)PVGR ddPTM_PC-9_Lapatinib_30min_R1 1 APYTCGGDSDQYVLMSSPVGR 21 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 APYTCGGDSDQYVLMS(0.369)S(0.631)PVGR 118.23 2.3038e-06 6156300.0 9239.0 10473.0 12383.0 10569.0 14713.0 14176.0 11008.0 11696.0 15534.0 12395.0 True False 9107.250165774902 10448.750411959198 11364.917539762315 11346.279517150442 13847.610266870946 13569.725525870015 11577.940377442334 12239.438858347212 13784.397339728164 14537.459234700673 0.6264678042251047 0.7187466697769446 0.781767801118537 0.7804857323394628 0.952546799499663 0.9334317164225855 0.7964211758410976 0.8419242084016907 0.9481985206070286 1.0 13.827487525712078 -3.706902268196521 0.4142514231111259 0.9199070315417985 1.4115680611940093e-15 0.725408137018197 0.059238577634829266 7.671464092601082 0.5178602310561852 0.04650267199672745 4.187473548196809 0.00019638021528915642 3.706902268196521 -0.9199070315417971 AQAAAPAS(ph)VPAQAPK ddPTM_PC-9_Lapatinib_30min_R1 2 AQAAAPASVPAQAPK 15 0 A0A3B3ITT5;P47914 A0A3B3ITT5 RPL29 60S ribosomal protein L29 1 AQAAAPAS(1)VPAQAPK;AQAAAPAS(1)VPAQAPK 155.2 0.00018864 9849900.0 106714.0 91774.0 112710.0 92441.0 94858.0 86683.0 87012.0 81810.0 88069.0 83923.0 True False 105192.23879104936 91561.50294157765 103443.4188731816 99239.4195141361 89278.63893800354 82975.77015794232 91517.05560701415 85611.19126208847 78149.74181231618 98428.97872963152 1.0687120820383134 0.9302291268619406 1.0509447543626753 1.008233761997376 0.9070361197512525 0.8430014334077705 0.9297775592937594 0.8697762830319368 0.7939708693613583 1.0 16.58679550522173 -6.3145828217202205 3.943114905010362 0.8814736676638585 1.0119408065958007 0.4980341499046671 0.0609809626811306 0.18580521887825371 6.012707313875313 0.01852760007175206 0.0217809824987036 4.846376814384628e-07 6.3145828217202205 0.13046713893194217 AQAAAPASVPAQAPK ddPTM_PC-9_Lapatinib_30min_R1 1 AQAAAPASVPAQAPK 15 0 A0A3B3ITT5;P47914 A0A3B3ITT5 RPL29 60S ribosomal protein L29 0 145.81 0.00052322 8804500.0 76992.0 67438.0 85498.0 72404.0 77862.0 78184.0 77395.0 64748.0 72612.0 92629.0 False True 75894.07996139646 67281.85145437827 78468.68447182424 77728.8316926636 73282.31024258184 74840.25257580566 81402.1344033566 67756.42845419509 64433.671921742105 108639.79922961601 0.6985845012562134 0.6193112646699069 0.7222830401773523 0.7154728952359307 0.6745438666330353 0.6888843048911274 0.7492846542481991 0.6236796177337208 0.5930945415828512 1.0 16.72919319298054 -10.63526635578176 4.762180632567794 1.0000171654627859 0.6779081089328493 0.8067854697244226 0.04754137960559632 9.950160648398831e-06 1.8545884383745802e-06 0.04751183555116176 0.011522630028450134 2.3159738116991393e-11 10.63526635578176 -0.3221090565299366 AQAEAQQPTFDALRDELR ddPTM_PC-9_AZD4547_30min_R2 3 AQAEAQQPTFDALRDELR 18 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ;; 137.81 0.00014197 16254400.0 38166.5 31300.6 39240.8 70306.0 56074.0 48455.0 36986.4 52826.9 40838.5 44666.8 False True 50302.65308748331 41417.906833406036 38720.44135251676 54098.037916872076 48289.093007695265 45425.101190089306 40278.11794784909 44663.71644639715 42997.13973654984 43103.02892751582 1.1670329055546127 0.9609047870639539 0.8983229790563203 1.2550866902612807 1.1203178572183543 1.0538726006118595 0.9344614276547191 1.036208302704338 0.9975433468691017 1.0 15.395501633206402 -7.019920223264934 22.695297972474965 0.9949415038523077 1.0746750298502552 0.1572027811893385 0.09622810003714263 532.4472222311881 606619.5490993181 0.03856485452953455 0.030364380270806023 9.551680273211833e-08 7.019920223264934 0.07973352599794747 AQAEAQQPTFDALRDELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AQAEAQQPTFDALRDELR 18 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ;; 164.93 1.9427e-07 10306400.0 37765.0 35393.7 43637.2 39898.2 51051.0 47150.5 40569.4 39452.7 43086.3 36085.0 False True 44157.86860725038 38907.35262718556 44677.67634300255 37662.833205709634 41047.92302266987 44677.84477628857 36726.37273497942 38417.10842859099 43716.35562622874 42626.92485129717 1.0359149472145566 0.9127412489386173 1.0481092994359638 0.8835456307743373 0.9629576415813339 1.0481132507715716 0.8615768757211162 0.901240438117645 1.025557339140274 1.0 15.379477361151872 -5.752787668384803 24.998341560864535 0.9509525694454203 0.9903037376320513 0.07916564282642735 0.06632998159345202 572.7055534122248 1654765.40680873 0.017889128143326785 0.03036927773358525 1.7669014681902373e-06 5.752787668384803 0.03935116818663098 AQAEAQQPTFDALRDELR ddPTM_PC-9_Lapatinib_30min_R1 2 AQAEAQQPTFDALRDELR 18 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 125.98 5.7036e-05 10649800.0 34339.0 37209.0 38744.0 34276.0 41996.0 35466.0 31298.1 38403.0 44859.0 31926.0 False True 33849.31956299863 37122.84484661415 35558.617876164986 36796.771381384126 39525.877847312746 33949.20185528401 32918.56247522056 40187.343577044114 39806.50703378819 37444.366561279014 0.9039896430776319 0.9914133488107301 0.9496386544013788 0.9827051372645048 1.0555894378030741 0.90665712824184 0.8791325771621262 1.0732547314233805 1.0630840013982732 1.0 15.192461063642106 -7.7855003803004434 24.999929959686675 1.0511270737408909 0.9574377278364616 0.4036121920891955 0.051284532957352434 249.81328236035714 259557.8510765443 0.029043208614360303 0.013962768722066947 1.638700626316257e-08 7.7855003803004434 -0.09368934590442923 AQASSIPVGSR ddPTM_PC-9_Lapatinib_30min_R1 1 AQASSIPVGSR 11 0 K7EK42;A0A494C0X0;Q99426;K7EP07;Q99426-2 K7EK42 TBCB Tubulin-folding cofactor B 0 92.23899999999999 0.035733 3094600.0 7554.4 7568.0 9730.8 8706.1 11710.0 11028.0 10657.0 7244.9 9231.9 10406.0 False True 7446.672870692705 7550.4767609765295 8930.771185974243 9346.375636698225 11021.24082274579 10556.358147523606 11208.767314898527 7581.524502807773 8192.106205783208 12204.663234876578 0.610149803184472 0.6186550677940836 0.73175072626775 0.7658036487225321 0.9030352260151687 0.8649446481536087 0.9184003769041217 0.6211989922952137 0.6712275503328177 1.0 13.575144866714686 -5.47813413384508 1.8657768115433793 0.816280921266375 0.6050060151217369 0.3744830142296085 0.10712736244767573 0.4401959606724365 2.934068537190705 0.0335339895832951 0.09759032703791695 3.3255682572810505e-06 5.47813413384508 -0.21127490614463806 AQAVASTSTVPSPSQTMPSCT(ph)SPSR ddPTM_PC-9_AZD4547_30min_R2 1 AQAVASTSTVPSPSQTMPSCTSPSR 25 0 A0A087X0D9;E7EV05;E9PFU9;B4DEN4;Q8WV99-2;Q8WV99 A0A087X0D9 ZFAND2B AN1-type zinc finger protein 2B 1 AQAVASTSTVPSPS(0.001)QT(0.002)MPS(0.274)CT(0.32)S(0.32)PS(0.084)R 86.07600000000001 8.1593e-05 0.0 5802.7 5557.3 7653.9 9109.3 8790.1 8751.0 7271.3 9830.4 6010.4 7797.0 True False 7647.837896342064 7353.5885460753825 7552.404285030584 7009.291622282051 7569.746343170492 8203.79858661586 7918.431613625407 8311.337560119237 6328.097473525204 7524.029403222093 1.016455078321059 0.9773471303722284 1.0037712348381227 0.9315874841318922 1.0060761245734662 1.0903464283516306 1.0524190150339412 1.1046391653599847 0.8410516671845085 1.0 12.877289771455121 -6.521636660995348 24.996555628128082 1.0288249746020328 0.981641544619076 0.041434142534526264 0.07099620409428437 123.94186119488569 2494357.997974784 0.022792479028892372 0.02309647725230645 3.008592295422661e-07 6.521636660995348 -0.04718342998295677 AQAVHIS(ph)APSAAASTPVPSAPIDPQAQLEADK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQAVHISAPSAAASTPVPSAPIDPQAQLEADK 32 0 H0YLX0;Q96KN3 H0YLX0 PKNOX2 Homeobox protein PKNOX2 1 AQAVHIS(0.496)APS(0.496)AAAS(0.004)T(0.004)PVPSAPIDPQAQLEADK 40.044000000000004 0.037255 6365500.0 1400.1 1642.1 3746.1 4258.0 3991.0 5602.7 2008.1 4213.4 4461.1 1147.0 True False 1637.1092767644966 1805.1168357391698 3835.421231163364 4019.4380646222594 3208.992199633217 5308.884549010342 1817.8782306149988 4102.802714466316 4526.335147927974 1354.942020352995 1.20825042855929 1.3322465527114535 2.8306902978506376 2.9665018902986704 2.368361266703646 3.9181636330292937 1.3416649593178884 3.0280282497973134 3.340611686652654 1.0 10.404015402854622 -5.255340612985038 21.785529962943766 2.6787423907846355 1.2702470094181202 0.28649674196545305 0.8313907913357731 92.1862206580979 329281.9060460026 0.20012558919283627 0.4976666577097048 5.55468437835044e-06 5.255340612985038 -1.4084953813665153 AQAVS(ph)EDAGGNEGR ddPTM_PC-9_AZD4547_30min_R2 2 AQAVSEDAGGNEGR 14 0 P55884;P55884-2;C9JZG1 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 1 AQAVS(1)EDAGGNEGR;AQAVS(1)EDAGGNEGR 188.44 3.6085000000000003e-06 17160800.0 21974.5 20143.1 30061.0 39333.0 32801.0 26785.0 25529.0 31896.0 27891.0 28837.0 True False 28961.933902005738 26653.963155210477 29662.371498491542 30265.384538792245 28247.147336473467 25110.129715747444 27801.031543773905 26967.2060971642 29365.261319394976 27827.425407299692 1.0407694379950954 0.9578307286817345 1.0659402033905194 1.0876099421994327 1.0150830313272055 0.9023518830153994 0.9990515161521604 0.9690873554579778 1.0552633198934702 1.0 14.764219816284308 -6.530867381503569 24.999948903957357 0.9812686677989881 1.0364321853822538 0.2173613193689803 0.047122638939700645 291.39776221607724 911904.1914955416 0.015925321357062244 0.01594948802951034 2.9453208955037563e-07 6.530867381503569 0.05516351758326565 AQAVS(ph)EDAGGNEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQAVSEDAGGNEGR 14 0 P55884;P55884-2;C9JZG1 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 1 AQAVS(1)EDAGGNEGR 128.82 2.4494e-05 7404100.0 8502.7 11778.0 10831.0 8922.5 12493.0 10894.0 11649.0 14683.0 9939.7 5513.4 True False 9942.039174020067 12947.242001909715 11089.252116796237 8422.601252135295 10045.086331750885 10322.699462209055 10545.522388543455 14297.58680792446 10085.049308435064 6512.935775949616 1.5265065580307324 1.9879271725233538 1.7026503098258132 1.2932111634261034 1.5423284794001004 1.5849533631711512 1.6191657266888786 2.195259910395755 1.5484644184080898 1.0 12.669092284992706 -11.381501486081163 2.0071200279916335 0.6491911182768864 1.6743206742040486 0.40709187546502046 0.24122868513291312 1562570.915866292 705512.6395206224 2614052.031484529 0.06644434688028086 4.1543062970713e-12 11.381501486081163 1.0251295559271623 AQAVS(ph)EDAGGNEGR ddPTM_PC-9_Lapatinib_30min_R1 1 AQAVSEDAGGNEGR 14 0 P55884;P55884-2;C9JZG1 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 1 AQAVS(1)EDAGGNEGR 152.25 0.00025131 9683100.0 14688.0 12982.0 13801.0 13724.0 13412.0 14873.0 12323.0 12932.0 15884.0 13569.0 True False 14478.54642655068 12951.940976611702 12666.335053400606 14733.30874192192 12623.13252900653 14236.916460656383 12961.024643097915 13532.867930587056 14094.976654064774 15914.383570443992 0.9097773949246811 0.813851250931635 0.7959048490526756 0.9257857005083407 0.7931901649304259 0.894594276783489 0.8144220343644964 0.8503545155038327 0.8856753132582402 1.0 13.95804365609056 -8.7225212745853 2.249432423269825 0.9999145932028295 0.8477523315048944 0.5034203440824229 0.04480993860869858 0.6216014454387733 5.453183460695566 0.040363092963102726 0.011022217230232589 1.894430710472132e-09 8.7225212745853 -0.15216226169793512 AQAVS(ph)EEEEEEEGK ddPTM_PC-9_AZD4547_30min_R2 3 AQAVSEEEEEEEGK 14 0 G3V529;Q9GZR7-2;Q9GZR7 G3V529 DDX24 ATP-dependent RNA helicase DDX24 1 AQAVS(1)EEEEEEEGK;AQAVS(1)EEEEEEEGK;AQAVS(1)EEEEEEEGK 140.96 1.5748e-05 19804200.0 37649.0 47666.4 42408.2 43050.0 42886.5 41604.4 45275.0 48155.0 39200.6 39583.6 True False 49620.598852152 63073.631632743934 41845.839558974345 33125.48761586977 36932.44974987559 39002.870291052575 49304.38729070327 40713.75124181538 41272.66368638894 38197.79021231015 1.2990437032182185 1.6512377098824147 1.0955041987085556 0.8672095278745808 0.9668739878563243 1.021076613968181 1.2907654347715054 1.0658666644201422 1.080498726679949 1.0 15.221201558596965 -5.351991488077745 6.509092708899832 1.0466698321390442 1.4727418621549409 0.6384254559335754 0.12870741976888736 0.13844855795347338 8.24116159355323 0.03490491513544874 0.07369126664704592 4.446399820718203e-06 5.351991488077745 0.42607203001589666 AQAVS(ph)EEEEEEEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQAVSEEEEEEEGK 14 0 G3V529;Q9GZR7-2;Q9GZR7 G3V529 DDX24 ATP-dependent RNA helicase DDX24 1 AQAVS(1)EEEEEEEGK 202.63 6.3809e-09 8628000.0 18304.0 30350.0 18154.0 19994.0 19578.0 12309.0 19127.0 13524.0 12227.0 14541.0 True False 21402.505679521 33362.94742383765 18586.8602094284 18873.801001422606 15741.831441848948 11663.494371243916 17315.15209251186 13169.00932986246 12405.796743788595 17177.168193507325 1.2459856850916078 1.9422844934619825 1.0820677774147844 1.0987725560349686 0.9164392677833294 0.6790114784841262 1.0080329829370065 0.7666577622986843 0.7222259573890517 1.0 14.068204594726353 -5.609406945699637 1.9135104983961528 0.8511242888662688 1.5908287773381755 0.6296830960905955 0.20950739730052076 0.19628773317186676 1.4336926994795116 0.05921621074576739 0.14166903742716044 2.4580632528109726e-06 5.609406945699637 0.7397044884719067 AQAVS(ph)EEEEEEEGK ddPTM_PC-9_Lapatinib_30min_R1 2 AQAVSEEEEEEEGK 14 0 G3V529;Q9GZR7-2;Q9GZR7 G3V529 DDX24 ATP-dependent RNA helicase DDX24 1 AQAVS(1)EEEEEEEGK;AQAVS(1)EEEEEEEGK 174.87 0.00012403 49110000.0 98479.0 100039.0 91372.0 80323.0 92019.0 78882.0 111409.0 112788.0 84428.0 92889.0 True False 97074.67140116302 99807.36584187787 83859.74686611985 86230.22136967297 86606.62333631465 75508.40074292317 117177.21289157645 118028.54223283748 74918.82957374598 108944.7398831875 0.8910450518790373 0.9161283596518116 0.7697457165535093 0.7915042200489033 0.7949592006844554 0.6930889992842667 1.0755655850591406 1.0833799076429922 0.6876773459101861 1.0 16.73323701574939 -7.2638544165875985 24.999225070500863 0.9686040306004979 0.8109887351986143 0.2861979429823821 0.11756746443829318 290.1975704529213 3003946.0172344274 0.04807443367584534 0.0341217676432406 5.446852106356168e-08 7.2638544165875985 -0.15761529540188368 AQAVS(ph)EEEEEEEGKSSSPK ddPTM_PC-9_AZD4547_30min_R2 1 AQAVSEEEEEEEGKSSSPK 19 1 G3V529;Q9GZR7-2;Q9GZR7 G3V529 DDX24 ATP-dependent RNA helicase DDX24 1 AQAVS(1)EEEEEEEGKSSSPK 80.609 0.006630500000000001 0.0 7718.4 10241.0 10230.0 17064.0 10005.0 11056.0 8930.4 8301.3 8523.3 9151.2 True False 10172.6906473067 13551.202976329876 10094.343515836743 13130.158436171942 8615.978448870972 10364.666572234602 9725.18829952283 7018.524829896825 8973.824237338182 8830.819273408499 1.1519532143454532 1.5345351950679673 1.1430812026957666 1.4868562054836385 0.9756714730665524 1.173692525159568 1.101278148541378 0.7947761824354301 1.0161938501403038 1.0 13.108331573821674 -6.72089550359091 0.9388211526405921 0.9465995459762524 1.3364076668673959 0.459968501084137 0.15758039474448873 0.46088719974696013 0.8805147927173567 0.08806513283144064 0.08447856754188518 1.9015357569655502e-07 6.72089550359091 0.3898081208911435 AQAVS(ph)EEEEEEEGKSSSPK ddPTM_PC-9_Lapatinib_30min_R1 1 AQAVSEEEEEEEGKSSSPK 19 1 G3V529;Q9GZR7-2;Q9GZR7 G3V529 DDX24 ATP-dependent RNA helicase DDX24 1 AQAVS(1)EEEEEEEGKSSSPK 101.67 0.00018055 10714000.0 23464.0 17758.0 17523.0 13231.0 13801.0 15765.0 16553.0 18684.0 13841.0 12018.0 True False 23129.399057229388 17716.882442048267 16082.326580736088 14204.05187732213 12989.252313809968 15090.76770000994 17410.03334554896 19552.12684929544 12282.08082780852 14095.295287021589 1.6409304371598414 1.2569358840152358 1.1409712427624046 1.0077158078696429 0.9215310533983617 1.0706244454420861 1.2351662729321786 1.3871385062289752 0.8713603069470558 1.0 13.782926081271857 -4.708372625862599 1.7930817559034908 1.0885056541368503 1.8962006045228903 0.5914154514471075 0.14218509960510065 0.825925713249759 2.352295254772629 0.041021399221125965 1.211209337644805 1.957164700190527e-05 4.708372625862599 0.80769495038604 AQAVSEDAGGNEGR ddPTM_PC-9_AZD4547_30min_R2 1 AQAVSEDAGGNEGR 14 0 P55884;P55884-2;C9JZG1 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 0 109.95 0.0024920000000000003 2381700.0 6774.0 9622.3 10037.0 13745.0 9616.7 11714.0 8309.9 10704.0 8534.9 10751.0 False True 8927.991092047003 12732.520300667806 9903.9028219407 10576.302608133103 8281.587201325086 10981.521728216005 9049.465001590606 9049.942753450141 8986.037389656316 10374.610762349716 0.86056154747004 1.2272769159567056 0.9546288577767897 1.0194409072690556 0.798255220463752 1.0584996372171203 0.8722703153772122 0.8723163654768717 0.8661565812442196 1.0 13.340769589574132 -6.051325768746845 22.169611422213286 0.910148718200894 1.027395841025827 0.17501473544177015 0.10976517241483684 152.56640869845106 65898.72615832045 0.030812188526971773 0.03977967424180926 8.88534369074833e-07 6.051325768746845 0.11724712282493299 AQAVSEDAGGNEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQAVSEDAGGNEGR 14 0 P55884;P55884-2;C9JZG1 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 0 102.97 0.009177600000000001 0.0 7895.7 8308.7 11588.0 14531.0 15474.0 12715.0 12040.0 9960.6 10610.0 9500.2 False True 9232.286062816544 9133.53282571466 11864.301867734726 13716.875180137627 12441.980781038437 12048.203016521764 10899.484037948607 9699.144804128071 10765.151177852047 11222.511056458181 0.8226577827698972 0.8138582158454293 1.0571878083298671 1.2222643498527919 1.108662822290426 1.0735746176510492 0.9712161550223037 0.8642579860544255 0.9592462082411638 1.0 13.45410789715194 -5.258657883716239 24.05433811899029 1.036043067776735 0.818257956319392 0.4686976640831847 0.09097028999691291 137.70087814130707 1190804.305069474 0.02744448817389451 0.06614969396792886 5.512417671375923e-06 5.258657883716239 -0.21778511145734292 AQAVSEEEEEEEGKSS(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 1 AQAVSEEEEEEEGKSSSPK 19 1 G3V529;Q9GZR7-2;Q9GZR7 G3V529 DDX24 ATP-dependent RNA helicase DDX24 1 AQAVSEEEEEEEGKS(0.057)S(0.471)S(0.471)PK 69.737 0.020850999999999998 0.0 17621.0 15955.0 10683.0 13155.0 14180.0 11530.0 11562.0 14305.0 8829.8 12074.0 True False 17369.721308704353 15918.057177772269 9804.684977572546 14122.462583793558 13345.960278952627 11036.888777742763 12160.623786699516 14969.662522969988 7835.294942083923 14160.974812406279 1.2265907918632075 1.1240791957222203 0.692373590621937 0.9972803970684998 0.9424464385926578 0.7793876427259416 0.8587419967759369 1.057106782638666 0.5533019474916024 1.0 13.789632960550717 -5.088111894247192 5.776593108765297 0.8676306563477291 1.2035335371618452 0.4320984738494117 0.14632665213322898 0.17852882051016428 9.070831816159226 0.035181462275011725 0.0987612964824237 8.163720092566992e-06 5.088111894247192 0.3359028808141161 AQAVSEEEEEEEGKSSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 AQAVSEEEEEEEGKSSSPK 19 1 G3V529;Q9GZR7-2;Q9GZR7 G3V529 DDX24 ATP-dependent RNA helicase DDX24 1 AQAVSEEEEEEEGKS(0.039)S(0.171)S(0.79)PK 79.332 0.0013312 5439600.0 18364.0 19897.0 12764.0 18888.0 19088.0 12494.0 18514.0 15142.0 11243.0 14322.0 True False 18102.125992454854 19850.929718968036 11714.593190464839 20277.086528520926 17965.281368451888 11959.66074493652 19472.564330302277 15845.552598588707 9976.694945961352 16797.53861713457 1.0776653892606336 1.181776102524855 0.6973993903199127 1.2071462962934933 1.069518682345885 0.7119888822721262 1.15925105303458 0.943325862184667 0.5939379080090031 1.0 14.035962226540926 -8.01506950975379 24.389455758888786 0.7875232032303028 1.0101658498478472 0.16758132522797087 0.1918099938353953 821.498669581315 1329556.4440938886 0.11660118634186353 0.04737704065393759 9.658962728686563e-09 8.01506950975379 0.2226426466175444 AQCETLS(ph)PDGLPEEQPQTTK ddPTM_PC-9_AZD4547_30min_R2 1 AQCETLSPDGLPEEQPQTTK 20 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659;A0A087X146 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 AQCET(0.192)LS(0.806)PDGLPEEQPQT(0.002)T(0.001)K 63.291000000000004 0.0048031 5781000.0 29197.0 24181.0 39877.0 46649.0 40543.0 38194.0 29634.0 44558.0 36123.0 37507.0 True False 38481.03866467322 31997.035364772248 39348.20492483104 35894.79376986549 34914.30427312103 35805.723142178744 32271.368591335176 37672.58494097829 38032.388033433876 36193.89134624228 1.0631915285524667 0.884045184826313 1.0871504406203134 0.9917362415244185 0.9646463249590846 0.9892753116720666 0.8916247297815257 1.0408547834934452 1.0507957729552744 1.0 15.143458605362206 AQCETLS(ph)PDGLPEEQPQTTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AQCETLSPDGLPEEQPQTTK 20 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659;A0A087X146 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 AQCET(0.01)LS(0.99)PDGLPEEQPQTTK;AQCET(0.009)LS(0.991)PDGLPEEQPQTTK 123.03 4.2576e-06 10824400.0 60386.0 61920.0 62667.0 66756.0 73159.0 67876.0 74908.0 73039.0 76024.0 60042.0 True False 70608.15712213468 68067.00838497614 64161.218945920926 63015.87774587207 58824.01912627582 64316.46307113097 67812.17195304448 71121.80364121744 77135.70717672244 70927.13930778952 0.9955026779767528 0.9596750841676867 0.9046074545244555 0.8884593169959049 0.8293584049824426 0.9067962376436556 0.9560821515551673 1.0027445676694102 1.0875344463279526 1.0 16.114050140342602 -7.72633580813444 2.2816396760608817 1.0431235934393415 0.9115893737995373 0.5644591847835521 0.045995080217364016 0.23865264930331864 2.4749191471422627 0.03294756548885711 0.014549092068683574 1.877864240324336e-08 7.72633580813444 -0.13153421963980416 AQCETLS(ph)PDGLPEEQPQTTK ddPTM_PC-9_Lapatinib_30min_R1 2 AQCETLSPDGLPEEQPQTTK 20 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659;A0A087X146 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 AQCET(0.063)LS(0.935)PDGLPEEQPQT(0.001)T(0.001)K;AQCET(0.029)LS(0.967)PDGLPEEQPQT(0.003)T(0.001)K 84.67399999999999 0.00044695 11483800.0 90773.0 100130.0 114639.0 107855.0 125237.0 128049.0 123256.0 108084.0 139802.0 104707.0 True False 89478.56037427044 99898.155136969 105213.82393933719 115787.01649373282 117870.80588541538 122572.64276679797 129637.59258376007 113105.97722004118 124056.02657967535 122805.46543669223 0.7286203432077522 0.8134666871847634 0.8567519659259485 0.9428490505858023 0.9598172643723195 0.998104134298369 1.0556337384722496 0.9210174548652212 1.0101832694378559 1.0 16.906015243475117 -5.320972431860833 0.864423267269982 0.9967700743724573 0.6889244935679681 0.8834677690250009 0.032808109393532764 0.3812361919413275 0.37525179980601076 0.013039058950691594 0.09585167014084264 4.77559587216488e-06 5.320972431860833 -0.3078455808044892 AQEEAERLEADR ddPTM_PC-9_AZD4547_30min_R2 4 AQEEAERLEADR 12 1 P15311;E7EQR4 P15311 EZR Ezrin 0 ;;; 89.35600000000001 0.009768299999999999 55772300.0 84739.0 69080.5 117990.0 227080.0 176297.0 118353.0 85979.0 112149.0 82225.1 125899.0 False True 111684.23931930508 91409.42068219461 116425.37550670354 174730.214351027 151821.20465773178 110952.36820040546 93630.96443660691 94818.94897764202 86571.35092013131 121491.31433067321 0.9192775626356681 0.7523946973970324 0.9583020493944013 1.4382115735076253 1.2496465734538613 0.9132535013854323 0.7706803153167278 0.7804586648850078 0.7125723464024986 1.0 16.890493650654868 -6.994277817598564 24.02862861035326 0.8039661412835364 1.0632653334165507 0.28031420191932244 0.1876580982267394 135.64803055878124 569607.3510689706 0.07507011635012902 0.06598511949697673 1.0132629953901543e-07 6.994277817598564 0.25929919213301433 AQEEAERLEADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AQEEAERLEADR 12 1 P15311;E7EQR4 P15311 EZR Ezrin 0 ;; 92.295 0.007697800000000001 34052900.0 63643.0 45007.0 71916.0 100988.0 105308.0 103679.0 84107.0 112997.0 93985.0 72631.0 False True 74416.50289345255 49474.997519099226 73630.75018294883 95329.96976751352 84673.65335980311 98241.89072355171 76139.77607805181 110030.94848021798 95359.35282284871 85798.42535332021 0.8673411264484563 0.5766422555584192 0.8581830013748555 1.1110923000619435 0.9868905287144226 1.1450313956111546 0.8874262641127291 1.282435522879442 1.1114347661994535 1.0 16.388663549933916 -5.599055165119699 3.9457544788581167 1.0775246547928943 0.7190639408415395 0.5942660607261734 0.11956416977528155 0.13505266876470337 4.089063296960632 0.031906409124167485 0.05925556774108306 2.517357146747802e-06 5.599055165119699 -0.3584607139513548 AQEEAERLEADR ddPTM_PC-9_Lapatinib_30min_R1 4 AQEEAERLEADR 12 1 P15311;E7EQR4 P15311 EZR Ezrin 0 ;;; 122.33 0.00052624 37280500.0 186536.0 134241.0 160943.0 137270.0 117824.0 119276.0 92749.0 97544.0 162668.0 112435.0 False True 183875.96243348747 133930.17321224243 147710.88779794576 147365.29371929655 110893.82397089677 114174.84352593627 97551.08939565763 102076.2503418793 144346.6168700208 131869.23993977992 1.3943809983090614 1.0156286126575362 1.1201314868076906 1.117510753732964 0.8409377654829748 0.865818621371261 0.7397562118368606 0.7740717273299973 1.0946193133132402 1.0 17.008748552584194 -3.381566517215776 0.5131243760675414 0.8706740980861242 3.125141997339569 0.5502859572574081 0.12633636134238965 12.628516683290211 0.8275581005057786 0.07208828762419758 23.428087304432353 0.00041536842789764163 3.381566517215776 2.2544678992534446 AQENYEGSEEVS(ph)PPQTK ddPTM_PC-9_AZD4547_30min_R2 2 AQENYEGSEEVSPPQTK 17 0 Q93008;Q93008-3 Q93008 USP9X Probable ubiquitin carboxyl-terminal hydrolase FAF-X 1 AQENYEGS(0.002)EEVS(0.998)PPQTK;AQENYEGSEEVS(1)PPQTK 242.1 6.386e-42 4043300.0 37913.0 34002.0 47795.0 50785.0 41299.0 40557.0 43833.0 49697.0 38393.0 41123.0 True False 49968.54536061087 44992.48155464976 47161.20707130179 39077.30287042851 35565.346722630915 38020.96437862866 47734.05208422739 42017.47057345024 40422.375599137034 39683.296286867015 1.2591833349576786 1.133788917871215 1.1884397588944633 0.9847292570642864 0.8962296495112753 0.9581100346044465 1.2028751779882947 1.0588200705331958 1.0186244435675726 1.0 15.276244247492029 -5.754143466718391 24.714176903618167 1.0197583650078241 1.1878025632556641 0.506562180997068 0.07984313756621725 139.3825383216095 472138.06535721757 0.024073164108980458 0.04060233777644628 1.7613940837495213e-06 5.754143466718391 0.16804419824784 AQENYEGSEEVS(ph)PPQTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQENYEGSEEVSPPQTK 17 0 Q93008;Q93008-3 Q93008 USP9X Probable ubiquitin carboxyl-terminal hydrolase FAF-X 1 AQENYEGSEEVS(1)PPQTK 199.31 1.2109999999999998e-53 0.0 11197.0 14082.0 12844.0 16415.0 13896.0 11551.0 11102.0 11444.0 13251.0 8698.6 True False 13092.430949169404 15479.967895304184 13150.249671141257 15495.32076814804 11173.17855327065 10945.245225626653 10050.338188480517 11143.60712592028 13444.77080657092 10275.587321920288 1.2741296958510697 1.5064801076899719 1.2797565004472908 1.507974219156584 1.0873518177822874 1.0651697934849744 0.978079196216915 1.0844739844844 1.3084187195694406 1.0 13.32693323595821 -6.2758840162502425 24.377405581769356 1.0849101445722105 1.3922327206699598 0.6463220827366135 0.11046370317888453 350.2363350989814 591072.8757631581 0.03344266959799219 0.03810165217626987 5.298049160004684e-07 6.2758840162502425 0.3073225760977494 AQENYEGSEEVS(ph)PPQTK ddPTM_PC-9_Lapatinib_30min_R1 4 AQENYEGSEEVSPPQTK 17 0 Q93008;Q93008-3 Q93008 USP9X Probable ubiquitin carboxyl-terminal hydrolase FAF-X 1 AQENYEGSEEVS(1)PPQTK;AQENYEGSEEVS(1)PPQTK;AQENYEGSEEVS(1)PPQTK;AQENYEGS(0.001)EEVS(0.999)PPQTK 197.94 1.5051e-53 6696600.0 62244.0 83967.0 102756.0 82705.0 89708.0 89745.0 79248.0 92235.0 94588.0 68805.0 True False 61356.389145848356 83772.579570417 94307.79832963082 88787.40159579217 84431.55181271382 85906.8155558129 83351.07367655786 96520.57482042215 83934.50338420297 80697.85257310048 0.7603224520784915 1.0381017201731766 1.1686531341611812 1.100244910672979 1.0462676405946634 1.06454896650433 1.0328784598208973 1.1960736468543396 1.0401082644444666 1.0 16.300242662428474 -4.774348720428543 3.9992505322243157 1.0862763009106124 0.7288561789272063 0.7303056674738282 0.058023077109403194 0.11364234864379068 3.4276740413455626 0.01416738070201697 0.11918326156822735 1.6813234859974635e-05 4.774348720428543 -0.3574201219834061 AQESGQGSTAGPLRPPPPGAGGPAT(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AQESGQGSTAGPLRPPPPGAGGPATPSK 28 1 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 AQESGQGSTAGPLRPPPPGAGGPAT(0.917)PS(0.083)K;AQESGQGSTAGPLRPPPPGAGGPAT(0.811)PS(0.189)K;AQESGQGSTAGPLRPPPPGAGGPAT(0.901)PS(0.099)K 84.18299999999999 3.7275999999999996e-07 35452900.0 59040.0 47568.0 60533.0 67704.0 86892.0 80869.0 69120.0 81057.0 64329.0 58852.0 True False 69034.30590684657 52290.23667403983 61976.33629268086 63910.76437932955 69866.13635944096 76628.0872782618 62572.45321453553 78929.3396369905 65269.689926488645 69521.4017278244 0.9929935845815536 0.7521458914012635 0.8914713275678418 0.919296256849647 1.0049586835571325 1.102222989954374 0.9000459090210244 1.1353243415027516 0.9388431231869984 1.0 16.085169550386944 -6.1036937393222965 2.442222693792269 1.020000344321398 0.8671267204249896 0.34873459168762855 0.0843065445312645 0.2919865299199872 3.416782427916012 0.025278878796983484 0.03580746817520751 7.876010032587791e-07 6.1036937393222965 -0.15287362389640846 AQESGQGSTAGPLRPPPPGAGGPAT(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 1 AQESGQGSTAGPLRPPPPGAGGPATPSK 28 1 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 AQESGQGSTAGPLRPPPPGAGGPAT(0.754)PS(0.246)K 82.946 2.7239999999999997e-06 13597000.0 21812.0 13761.0 20322.0 25135.0 17445.0 18585.0 15919.0 14645.0 19156.0 16434.0 True False 21500.95688016908 13729.13724997332 18651.203605188537 26983.511747902 16418.91939818962 17790.16287375101 16743.207927734795 15325.460164201015 16998.44955837727 19274.59500307146 1.1155075827400183 0.7122918664587009 0.9676573542643265 1.3999522035924545 0.8518425105987036 0.9229850417565765 0.8686671717391062 0.7951119160614716 0.8819095579268214 1.0 14.234412926164527 AQESGQGSTAGPLRPPPPGAGGPATPS(ph)K ddPTM_PC-9_AZD4547_30min_R2 2 AQESGQGSTAGPLRPPPPGAGGPATPSK 28 1 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 AQESGQGSTAGPLRPPPPGAGGPAT(0.477)PS(0.523)K;AQESGQGSTAGPLRPPPPGAGGPAT(0.313)PS(0.687)K 66.47399999999999 0.00012656 26238700.0 51942.0 45383.0 57540.0 92194.0 86086.0 65672.0 53921.0 63243.0 51758.0 71910.0 True False 68458.47553928332 60052.16723706463 56776.98200403186 70940.097683101 74134.44485252438 61565.519458374634 58719.86454118185 53470.247529563436 54493.822213948784 69392.45278770065 0.9865406508792139 0.865399115099567 0.8182011115493413 1.0223027841390075 1.0683358474059332 0.887207714745698 0.8461995819751389 0.7705484585355468 0.7852989774070568 1.0 16.08249114151942 -6.997103499386256 24.991327981350658 0.8364354718872317 0.9471892568384739 0.22086972124061333 0.08888159078919747 133.31960937147815 1150282.7383232343 0.033150201832526864 0.029078609087336813 1.0066917293711469e-07 6.997103499386256 0.11075378495124222 AQFSVAGVHTVPGS(ph)PQAR ddPTM_PC-9_AZD4547_30min_R2 2 AQFSVAGVHTVPGSPQAR 18 0 A0A087WWW7;E9PGF5;E9PF55;A0A494C067;A0A2R8Y4T1;Q9HBL0;H0Y4U1 A0A087WWW7 TNS1 Tensin-1 1 AQFSVAGVHTVPGS(1)PQAR;AQFSVAGVHT(0.007)VPGS(0.993)PQAR 96.708 0.00046345 16583100.0 32929.0 30983.0 69327.0 106106.0 89796.0 73194.0 56376.0 88475.0 65165.0 83612.0 True False 43399.73703425094 40997.64884441251 68407.67868254296 81644.90102135841 77329.37539178575 68617.16760927447 61393.35478521671 74803.22170324197 68609.4888630157 80684.7693295121 0.5378925588422869 0.5081212871413241 0.84783880837745 1.0118997885204974 0.9584135399331304 0.8504351958799782 0.7609038892394879 0.927104611252587 0.8503400261679918 1.0 16.300008744668773 -5.302352401382341 4.649421500135942 0.9003301654891717 0.5194947369329798 0.8147708233474443 0.07234294531549697 0.0783702823832507 4.022859747741001 0.02022414555749303 0.046608862119262504 4.984798397348379e-06 5.302352401382341 -0.3808354285561919 AQFSVAGVHTVPGS(ph)PQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AQFSVAGVHTVPGSPQAR 18 0 A0A087WWW7;E9PGF5;E9PF55;A0A494C067;A0A2R8Y4T1;Q9HBL0;H0Y4U1 A0A087WWW7 TNS1 Tensin-1 1 AQFSVAGVHT(0.001)VPGS(0.999)PQAR;AQFSVAGVHT(0.009)VPGS(0.991)PQAR 71.428 0.005118899999999999 12296200.0 22849.0 24735.6 39559.0 50660.0 53800.0 42095.0 44532.0 45168.0 42949.0 38465.0 True False 26716.88441167917 27191.18689611461 40502.236588342945 47821.684441936 43258.27620653147 39887.46409598772 40313.60657623981 43982.38785945188 43577.047873474796 45438.400011227524 0.5879803075169373 0.5984186698782494 0.8913658178618771 1.0524508880180548 0.9520202338956177 0.8778360172482261 0.8872144830425056 0.9679563507646425 0.9590357024610725 1.0 15.471624414732995 -5.298033171331286 3.9630509917447077 0.9501227496643257 0.5857863509002046 0.8988313811127342 0.048026747451594166 0.06188585236490944 2.1416762708408252 0.013707516822520707 0.03351462844216372 5.034621529742358e-06 5.298033171331286 -0.36433639876412116 AQFSVAGVHTVPGS(ph)PQAR ddPTM_PC-9_Lapatinib_30min_R1 2 AQFSVAGVHTVPGSPQAR 18 0 A0A087WWW7;E9PGF5;E9PF55;A0A494C067;A0A2R8Y4T1;Q9HBL0;H0Y4U1 A0A087WWW7 TNS1 Tensin-1 1 AQFSVAGVHTVPGS(1)PQAR;AQFSVAGVHTVPGS(1)PQAR 110.91 0.00012147 14282600.0 100179.0 71539.0 125776.0 84763.0 94857.0 102319.0 68323.0 78133.0 115625.0 69213.0 True False 98750.42908942158 71373.35584084317 115435.18278940047 90996.75378107895 89277.69775603742 97943.05488723853 71860.4306329936 81763.34441853978 102602.09491477204 81176.37482947462 1.216492228149685 0.8792380294239004 1.4220292915505595 1.1209758254447033 1.0997990233436892 1.20654630233224 0.8852382332168587 1.0072307933225424 1.2639403413900405 1.0 16.30877229321996 -7.211986357471819 24.99865936000406 1.0397041253687473 1.152603830513916 0.12484225510806657 0.15325525284511066 859.7318478124105 434597.44414911506 0.057703629826150245 0.04469698687749 6.137812856238314e-08 7.211986357471819 0.11289970514516856 AQGAGVTLPPT(ph)PSGSR ddPTM_PC-9_AZD4547_30min_R2 5 AQGAGVTLPPTPSGSR 16 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 AQGAGVTLPPT(0.856)PS(0.132)GS(0.012)R;AQGAGVT(0.001)LPPT(0.811)PS(0.166)GS(0.022)R;AQGAGVTLPPT(0.776)PS(0.216)GS(0.008)R;AQGAGVTLPPT(0.976)PS(0.023)GSR;AQGAGVTLPPT(0.905)PS(0.093)GS(0.002)R 187.56 1.1751e-07 31800600.0 108182.0 101188.0 145566.0 181096.0 159900.0 172983.0 143134.0 185255.0 148788.0 155931.0 True False 142581.62567461308 133895.0421608112 143635.6997288652 139347.11510530894 137700.64507490938 162166.34566433198 155872.64871270044 156628.09648639793 156652.62992327774 150471.90315170275 0.9475631176862643 0.8898341773867305 0.9545682397866303 0.9260673400589742 0.9151252970867415 1.077718446219419 1.035892053252977 1.0409125770708745 1.0410756203790665 1.0 17.199134599508625 -6.753706730246735 24.999999874308774 1.041475047485963 0.9261079971343065 0.8455695887066069 0.024025274889567794 59.98629295084976 193938.13014416207 0.007588423814698311 0.007451070822023144 1.763166272884675e-07 6.753706730246735 -0.11536705035165662 AQGAGVTLPPT(ph)PSGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AQGAGVTLPPTPSGSR 16 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 AQGAGVT(0.004)LPPT(0.969)PS(0.025)GS(0.001)R;AQGAGVTLPPT(0.776)PS(0.223)GS(0.001)R;AQGAGVT(0.005)LPPT(0.604)PS(0.351)GS(0.04)R;AQGAGVT(0.001)LPPT(0.989)PS(0.009)GS(0.002)R 130.95 2.9239000000000002e-05 11663100.0 53523.0 56081.0 63832.0 64657.0 74796.0 57791.0 74740.0 63787.0 68171.0 62355.0 True False 62583.3867725635 61648.35105358284 65353.99696420807 61034.4779108223 60140.26072757852 54760.338224758845 67660.08612925891 62112.65883791307 69167.87190813875 73659.46789809162 0.8496312634127094 0.8369372303757849 0.8872450321610491 0.8286032963917676 0.8164634152772184 0.7434256557557564 0.9185524693562422 0.8432406669546725 0.9390221499269175 1.0 16.16858335507169 -8.414643680272956 1.2660197906615906 1.000717071937902 0.8346080944818413 0.6088475106971128 0.04288031827772752 0.30368553796420933 1.0441764299074863 0.04118041609312408 0.012834070149293147 3.849074523488047e-09 8.414643680272956 -0.16610897745606068 AQGAGVTLPPT(ph)PSGSR ddPTM_PC-9_Lapatinib_30min_R1 4 AQGAGVTLPPTPSGSR 16 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 AQGAGVTLPPT(0.68)PS(0.208)GS(0.111)R;AQGAGVTLPPT(0.99)PS(0.01)GSR;AQGAGVT(0.002)LPPT(0.973)PS(0.025)GSR;AQGAGVTLPPT(0.963)PS(0.037)GSR 156.72 3.5666999999999996e-05 28063300.0 205952.0 165781.0 186470.0 185275.0 200743.0 201480.0 207416.0 195439.0 229505.0 173067.0 True False 203015.08671302928 165397.14428005452 171139.156395016 198900.74155928192 188935.69141592315 192863.1700728195 218154.98558571775 204519.8094251473 203655.7301052087 202981.40035271837 1.0001659578673334 0.8148389162388567 0.8431272820939728 0.9798963905739859 0.930802975482541 0.9501519338110954 1.0747535744981187 1.0075790642381799 1.0033221258268914 1.0 17.63098801047647 -6.598595894486922 1.1438942492153306 1.0202618784650268 0.8894430984411136 0.4325437509896509 0.056670962843777824 0.4309128443996809 1.1960696559686055 0.027769308082376945 0.029390902462538972 2.5200206844910684e-07 6.598595894486922 -0.13081878002391323 AQGAGVTLPPTPS(ph)GSR ddPTM_PC-9_AZD4547_30min_R2 1 AQGAGVTLPPTPSGSR 16 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 AQGAGVT(0.003)LPPT(0.102)PS(0.831)GS(0.065)R 73.593 0.01426 8250900.0 24086.0 45483.0 38175.0 36195.0 41074.0 54903.0 46955.0 59756.0 31157.0 25461.0 True False 31744.84698007735 60184.49028145801 37668.774556898126 27850.801957175536 35371.584088848205 51469.90673077029 51133.904036111984 50522.083256274906 32803.89541172381 24569.618139725237 1.2920366445887446 2.4495492741968623 1.5331444853020975 1.1335463904563148 1.4396472866486223 2.094859856513256 2.08118432062387 2.0562828029707383 1.335140628770499 1.0 14.58458781510033 -6.7335949316358485 24.996204454704316 1.8024923497535126 1.5922229920781512 0.004444118758824667 0.4639227933713177 832.5111455564978 747350.5846139565 0.15566674188860474 0.1556353869329097 1.8467370759100345e-07 6.7335949316358485 -0.21026935767536137 AQGAGVTLPPTPS(ph)GSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQGAGVTLPPTPSGSR 16 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 AQGAGVTLPPT(0.164)PS(0.747)GS(0.089)R 144.3 1.347e-07 0.0 10597.0 10603.0 10141.0 11098.0 17088.0 11965.0 10520.0 17776.0 15003.0 11191.0 True False 12390.862799709572 11655.595767214187 10382.799899956673 10476.215040201456 13739.72906723439 11337.534336821305 9523.469441795616 17309.398835228854 15222.390492112565 13219.839712092735 0.9372929679605069 0.8816745150512173 0.7853952942000573 0.7924615780793793 1.0393264492205674 0.8576151136273152 0.7203922021145313 1.3093501292148975 1.151480715623807 1.0 13.690417064112843 -7.76194912137384 24.999993830817832 1.1728115770389227 0.8614979710063302 0.6068296404816795 0.10826832803238158 8.634024920680769 423364.79115216265 0.05472847912721465 0.02879998458561516 1.7300190231656328e-08 7.76194912137384 -0.3113136060325925 AQGAGVTLPPTPS(ph)GSR ddPTM_PC-9_Lapatinib_30min_R1 1 AQGAGVTLPPTPSGSR 16 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 AQGAGVTLPPT(0.123)PS(0.871)GS(0.005)R 128.45 2.0926e-05 8020200.0 48701.0 36716.0 41900.0 36609.0 40332.0 41904.0 39213.0 29935.0 43333.0 38868.0 True False 48006.51480933043 36630.98635782432 38455.1437386773 39301.34798404397 37959.75105576288 40111.863602995036 41243.257269317415 31325.889383090296 38452.3812232806 45586.28201164545 1.0530912522558147 0.8035528396122891 0.8435683289296014 0.8621310238462541 0.8327011851079607 0.8799108379303247 0.9047295688378673 0.6871779842692106 0.8435077292212068 1.0 15.476312128254335 -4.754793257745061 24.9786067283403 0.8431892914032301 1.0530916114856572 0.3928614782847063 0.0749032038532259 220.63272317275636 829144.1854252798 0.01792557772878077 0.16862521174351805 1.7587606580069823e-05 4.754793257745061 0.20990232008242715 AQGEPVAGHES(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 AQGEPVAGHESPK 13 0 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;D6RHZ5;H7BXG7;O94979-7;O94979-6;O94979-10;O94979-4;H0YAB3 D6REX3 SEC31A Protein transport protein Sec31A 1 AQGEPVAGHES(1)PK;AQGEPVAGHES(1)PK;AQGEPVAGHES(1)PK 135.61 5.1719e-05 11869200.0 83413.0 125321.0 96462.0 94327.0 90213.4 111856.0 117767.0 113016.0 104279.0 99988.2 True False 109936.5989018184 165828.56246427482 95182.85085284877 72581.36748762248 77688.82660663429 104861.62663747062 128248.03485509078 95551.97404932 109790.97505020213 96487.64355203943 1.1393852606891104 1.7186507656271781 0.9864771005783043 0.7522348439204717 0.8051686593914357 1.0867881396742245 1.3291653742784357 0.9903027012757878 1.1378760119785465 1.0 16.55805657863892 -5.2882101867202875 24.418112109923104 1.0081320295711735 1.4290180292440648 0.410506162326123 0.20034656523128533 474.5877661856087 432878.9553400397 0.05462823157842306 0.11377431982247373 5.1497934825861e-06 5.2882101867202875 0.4208859996728913 AQGEPVAGHES(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AQGEPVAGHESPK 13 0 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;D6RHZ5;H7BXG7;O94979-7;O94979-6;O94979-10;O94979-4;H0YAB3 D6REX3 SEC31A Protein transport protein Sec31A 1 AQGEPVAGHES(1)PK;AQGEPVAGHES(1)PK;AQGEPVAGHES(1)PK;AQGEPVAGHES(1)PK 76.574 0.011673000000000001 39518300.0 290028.0 420400.0 285135.0 279660.0 312657.0 240615.0 302307.0 211363.0 204309.0 210665.0 True False 339124.0120858893 462134.5336731921 291933.6997805091 263991.5568699534 251394.10527705462 227996.72582150067 273670.2924468542 205814.94520760977 207296.63261034607 248856.89687677767 1.3627269982949586 1.857029238382007 1.17309869022863 1.0608167190988873 1.0101954514105078 0.9161760380480595 1.0997094952219184 0.827041355054426 0.8329953286887994 1.0 17.924956845185093 -5.478488875196184 3.571446493281118 0.9660766397873329 1.608286503256874 0.7639898723117317 0.14119389613911332 0.10054705001821207 2.6003881085122 0.03754770853644228 0.08090716114796692 3.322852968582344e-06 5.478488875196184 0.6422098634695411 AQGEPVAGHES(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 AQGEPVAGHESPK 13 0 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;D6RHZ5;H7BXG7;O94979-7;O94979-6;O94979-10;O94979-4;H0YAB3 D6REX3 SEC31A Protein transport protein Sec31A 1 AQGEPVAGHES(1)PK;AQGEPVAGHES(1)PK;AQGEPVAGHES(1)PK;AQGEPVAGHES(1)PK 147.53 0.00010025 17744600.0 58997.0 67554.0 41181.2 53783.0 59012.0 49703.0 63036.0 60838.0 46143.2 48848.5 True False 58155.69196127526 67397.58286350525 37795.440700029045 57738.381234828485 55541.03018205588 47577.31855335198 66299.69564248309 63664.755580038276 40946.06690656266 57291.898138465156 1.0150770676286978 1.1763894207278016 0.659699572331914 1.007793128014091 0.9694395191414724 0.8304371141337537 1.1572263757477115 1.1112348804742158 0.7146920984814067 1.0 15.80604351605558 -9.623453502982791 15.599308324689416 1.0000006480932508 0.9658278344256748 0.004038686199631214 0.16775777992473812 0.0 0.0 0.1592011331803485 0.03861194634238832 2.379833080192496e-10 9.623453502982791 -0.034172813667576074 AQGEPVAGHES(ph)PKIPYEK ddPTM_PC-9_AZD4547_30min_R2 6 AQGEPVAGHESPKIPYEK 18 1 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;D6RHZ5;H7BXG7;O94979-7;O94979-6;O94979-10;O94979-4;H0YAB3 D6REX3 SEC31A Protein transport protein Sec31A 1 AQGEPVAGHES(0.969)PKIPY(0.031)EK;AQGEPVAGHES(1)PKIPYEK;AQGEPVAGHES(0.996)PKIPY(0.004)EK;AQGEPVAGHES(0.999)PKIPY(0.001)EK;AQGEPVAGHES(0.873)PKIPY(0.127)EK;AQGEPVAGHES(0.996)PKIPY(0.004)EK 99.95700000000001 0.00029119 597481600.0 827348.0 680698.0 771224.0 974008.0 913761.0 806532.0 811573.0 830915.0 772192.0 867284.0 True False 1090427.4540925433 900720.3167251043 760997.0658511897 749465.5038735899 786901.0578129742 756099.4265410183 883801.4247747762 702516.1792771867 813008.4926587886 836920.6511407058 1.3029042270689735 1.0762314390228522 0.909282217870913 0.895503657189106 0.9402337685662842 0.9034302421746556 1.0560157926204508 0.8394059560122833 0.9714284042945703 1.0 19.674731321068577 -4.860168509196945 2.3984824446191237 0.935288975551722 1.3545876775826684 0.7890951101080464 0.057769750798239546 0.18753993383681997 1.5370503133036024 0.014552533074852499 0.15485436597587754 1.379848770064503e-05 4.860168509196945 0.41929870203094644 AQGEPVAGHES(ph)PKIPYEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 AQGEPVAGHESPKIPYEK 18 1 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;D6RHZ5;H7BXG7;O94979-7;O94979-6;O94979-10;O94979-4;H0YAB3 D6REX3 SEC31A Protein transport protein Sec31A 1 AQGEPVAGHES(0.996)PKIPY(0.004)EK;AQGEPVAGHES(0.969)PKIPY(0.031)EK;AQGEPVAGHES(1)PKIPYEK;AQGEPVAGHES(0.993)PKIPY(0.007)EK;AQGEPVAGHES(1)PKIPYEK;AQGEPVAGHES(0.974)PKIPY(0.026)EK 108.28 0.00013022 586107100.0 1162962.0 1017472.0 982481.0 1387218.0 1464525.0 1243882.0 1357887.0 1330083.0 1162155.0 1091318.0 True False 1359828.4970534905 1118479.895921811 1005907.0731199415 1309496.6728814386 1177561.8394306798 1178650.638190887 1229258.1131094624 1295169.730589428 1179149.3182937459 1289165.3145314653 1.0548131273200652 0.8676000535496192 0.7802777981856646 1.015770947388049 0.9134296634862948 0.9142742400102939 0.9535302410429995 1.0046575997587595 0.914661064025211 1.0 20.298005847113963 -7.403269095910358 4.193424704904724 0.9712476065788543 0.9190287203846796 0.07837869947869203 0.07412230702605647 0.6187597721120535 18.162188212246374 0.033259653099127866 0.021540657587209865 3.9512172037258e-08 7.403269095910358 -0.052218886194174696 AQGEPVAGHES(ph)PKIPYEK ddPTM_PC-9_Lapatinib_30min_R1 5 AQGEPVAGHESPKIPYEK 18 1 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;D6RHZ5;H7BXG7;O94979-7;O94979-6;O94979-10;O94979-4;H0YAB3 D6REX3 SEC31A Protein transport protein Sec31A 1 AQGEPVAGHES(0.893)PKIPY(0.107)EK;AQGEPVAGHES(0.994)PKIPY(0.006)EK;AQGEPVAGHES(0.997)PKIPY(0.003)EK;AQGEPVAGHES(1)PKIPYEK;AQGEPVAGHES(0.964)PKIPY(0.036)EK 100.94 0.00026249 644256000.0 863570.0 596089.0 657559.0 646257.0 656840.0 599531.0 550300.0 621014.0 636688.0 547863.0 True False 851255.3334406565 594708.7925441002 603497.0372711429 693784.895630155 618205.9625971254 573890.4567050212 578791.8413614207 649868.5775630664 564977.4928181312 642560.3895684392 1.3247865060782573 0.9255298057565026 0.9392067221517774 1.0797193647372498 0.9620978395701129 0.8931307718648226 0.900758669158167 1.01137354264793 0.8792597582891551 1.0 19.293472523508647 -4.758666071974085 24.999967146753068 0.9549848694193462 1.3247870006955627 0.7817809543537421 0.05867930353448093 35.07069946711221 316084.5999484921 0.014875735702693727 0.10018716706197843 1.7431466596943035e-05 4.758666071974085 0.3698021312762164 AQGGQTQS(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 2 AQGGQTQSPTK 11 0 B7Z385;A0A087X0J3;A0A087WZ15;E9PDI2;P40123-2;P40123 B7Z385 CAP2 Adenylyl cyclase-associated protein;Adenylyl cyclase-associated protein 2 1 AQGGQT(0.001)QS(0.606)PT(0.393)K;AQGGQT(0.002)QS(0.549)PT(0.448)K 114.87 0.0022993 0.0 38555.0 34540.0 24859.3 26181.0 25459.0 25599.3 19613.9 29125.5 26939.7 37910.0 True False 50814.68800618133 45704.37953348636 24529.649439221917 20145.374942417813 21924.457304328458 23998.571724186433 21359.49910284096 24624.823212407693 28363.67754351241 36582.78243890597 1.3890328897492406 1.2493412607368959 0.6705244326395062 0.5506791337170982 0.5993108189882159 0.6560072833241857 0.5838675376459345 0.6731260328142529 0.7753286013954888 1.0 15.158877188319773 -5.21826153577938 3.9629544445729086 0.6614366987845693 1.3536357804288202 0.8065933922720552 0.12361295372587029 0.07996509479504685 2.7094207058990767 0.030676245614660713 0.08740388582880543 6.0497644314511165e-06 5.21826153577938 0.6921990816442508 AQGGQTQS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AQGGQTQSPTK 11 0 B7Z385;A0A087X0J3;A0A087WZ15;E9PDI2;P40123-2;P40123 B7Z385 CAP2 Adenylyl cyclase-associated protein;Adenylyl cyclase-associated protein 2 1 AQGGQT(0.029)QS(0.837)PT(0.135)K;AQGGQTQS(0.995)PT(0.005)K 132.14 0.00012319999999999999 3292800.0 6665.200000000001 8487.7 7365.9 7410.5 21185.6 26171.0 11177.3 17858.1 19680.7 31642.0 True False 7793.486716299353 9330.30276274487 7541.530991331308 6995.31371016516 17034.433762102097 24798.54668858759 10118.505227355723 17389.343797220998 19968.493005273587 37378.444122065805 0.2085021701504848 0.24961720536775542 0.20176150100585052 0.18714833841988573 0.45572880739693694 0.6634451291659874 0.27070429133732765 0.46522385309653536 0.5342248312974988 1.0 15.189918897693618 -12.910199258281594 0.12237374911440982 2.4550594850511644 9.340782135207986e-12 0.7775232487690409 0.11647600047857296 46.63156598298477 0.5452333763579743 18.58375432291299 1.2696152423471727 1.22970444171436e-13 12.910199258281594 -2.4550594850418235 AQGGQTQS(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 3 AQGGQTQSPTK 11 0 B7Z385;A0A087X0J3;A0A087WZ15;E9PDI2;P40123-2;P40123 B7Z385 CAP2 Adenylyl cyclase-associated protein;Adenylyl cyclase-associated protein 2 1 AQGGQT(0.135)QS(0.615)PT(0.251)K;AQGGQT(0.002)QS(0.51)PT(0.488)K;AQGGQT(0.009)QS(0.496)PT(0.496)K 141.58 0.00013251 11499900.0 31455.6 35989.1 17055.6 31609.0 31072.5 16795.5 74505.0 57604.0 26413.5 27222.6 True False 31007.037375749424 35905.7694501137 15653.354404519916 33933.631304532915 29244.87664088545 16077.195617222767 78362.50434423522 60280.49213374085 23438.533483514217 31927.99013816559 0.9711553167477557 1.124585960304254 0.49027058505033955 1.062817645510666 0.9159635954011135 0.5035454955871042 2.4543513075871144 1.888013992515103 0.7341061364052672 1.0 14.962534117895455 -7.2319164709659995 24.995289537022124 1.5931194872806205 0.8544842579286694 0.31657160774163495 0.4804100088088332 780.7873768090601 661047.0792425759 0.182803958899276 0.14157857209587607 5.862509088966463e-08 7.2319164709659995 -0.738635229351951 AQGGQTQSPT(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 AQGGQTQSPTK 11 0 B7Z385;A0A087X0J3;A0A087WZ15;E9PDI2;P40123-2;P40123 B7Z385 CAP2 Adenylyl cyclase-associated protein;Adenylyl cyclase-associated protein 2 1 AQGGQT(0.003)QS(0.227)PT(0.77)K 96.059 0.014577000000000001 2698900.0 12699.0 9606.8 9973.1 6665.3 6116.3 6983.7 6075.1 8048.3 11338.0 12603.0 True False 16737.017844391037 12712.010228786816 9840.850177692217 5128.718062858462 5267.157320022945 6547.008134995912 6615.772130971868 6804.620166535203 11937.30353301424 12161.772806054649 1.3761988577897655 1.045243192049948 0.8091624744702534 0.42170809672625753 0.4330912445100709 0.5383267916118719 0.5439809011790004 0.5595089034345037 0.9815430466741938 1.0 13.57006592346944 -5.108323236021774 1.8462513008054047 0.6070303972650739 1.395769314927923 0.5801140436143406 0.19721472173229854 0.3117652029898267 1.6934108809881836 0.05522744363093283 0.3397588690294658 7.792499157210609e-06 5.108323236021774 0.7887389176628492 AQGGQTQSPT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 AQGGQTQSPTK 11 0 B7Z385;A0A087X0J3;A0A087WZ15;E9PDI2;P40123-2;P40123 B7Z385 CAP2 Adenylyl cyclase-associated protein;Adenylyl cyclase-associated protein 2 1 AQGGQT(0.001)QS(0.327)PT(0.672)K 98.40700000000001 0.012198 4772100.0 8336.8 8396.9 2854.6 7549.9 7371.5 3775.4 16529.0 10749.0 6171.3 7016.4 True False 8217.915703218123 8377.457493953998 2619.905807074658 8105.144831728086 6937.922862926609 3613.9349428872524 17384.790742981855 11248.437781153743 5476.223207330015 8229.175391234672 0.9986317355650796 1.018019071859529 0.3183679630726132 0.9849279479887258 0.8430884667152138 0.43916124897965414 2.1125799264771183 1.366897319157281 0.6654643930864602 1.0 13.006532156550833 -7.217820731782333 24.999985650666474 1.3168125911291018 0.7714088086373202 0.2817832250620499 0.40486909861078346 591.6135716585052 339083.11374323943 0.15533713086093762 0.12032282459232273 6.055907991357074e-08 7.217820731782333 -0.5454037824917816 AQGVRS(ph)PLLR ddPTM_PC-9_AZD4547_30min_R2 2 AQGVRSPLLR 10 1 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 AQGVRS(1)PLLR;AQGVRS(1)PLLR 65.695 0.022713999999999998 80817000.0 36367.0 26877.5 51346.0 85961.0 70568.0 54321.0 44458.0 54848.0 36066.0 54586.0 True False 47930.94951940852 35565.126256840784 50665.118491119574 66144.0195342109 60770.85129234654 50924.299282774606 48414.675873441985 46372.50188165484 37972.37512980168 52674.96075468534 0.9099380205071183 0.6751808781115671 0.9618444468724736 1.2557013538605724 1.1536952362501967 0.9667648262698513 0.9191212519154197 0.8803519018764545 0.7208809382249821 1.0 15.684829713717006 -10.234055269591481 6.965076551189647 1.0000000000566789 0.9453851899065219 0.010887413614000807 0.1643183942699951 2.580202449350691e-10 0.0 0.17720722672886263 0.04297906549563988 5.833708580604353e-11 10.234055269591481 -0.05461481015015701 AQGVRS(ph)PLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AQGVRSPLLR 10 1 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 AQGVRS(1)PLLR;AQGVRS(1)PLLR 66.023 0.02231 38266000.0 42884.0 33441.0 49382.0 64019.0 83202.0 90217.0 78317.0 90739.0 90533.0 63421.0 True False 50143.41420239179 36760.80147613031 50559.454162277885 60432.2229823984 66899.16537055437 85485.86170204818 70898.24679402164 88357.19739591778 91856.87385339107 74918.72525964012 0.6693041563189119 0.49067574693417704 0.674857373601297 0.8066370960392485 0.8929565357486666 1.141048001094337 0.9463354661777145 1.1793740094976919 1.2260869833950017 1.0 16.19303873191683 -6.195807158922644 1.0184873319317511 1.1187086585531627 0.5633118003885422 0.8399980479038114 0.09250194917938175 0.19501423380052155 0.42275143210988536 0.04052548237000011 0.06761227159191832 6.370783419133877e-07 6.195807158922644 -0.5553968581646205 AQGVRS(ph)PLLR ddPTM_PC-9_Lapatinib_30min_R1 3 AQGVRSPLLR 10 1 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 AQGVRS(1)PLLR;AQGVRS(1)PLLR;AQGVRS(1)PLLR 67.252 0.020799 105211000.0 151739.0 118901.0 154443.0 127464.0 138953.0 151105.0 120370.0 120516.0 164148.0 114537.0 True False 149575.17403447555 118625.69203975573 141745.29270722048 136838.12776743932 130780.05773210891 144642.59139295912 126602.16962506667 126115.61332528845 145659.92368492964 134334.56783904054 1.1134526015202304 0.8830615525699449 1.0551661793936722 1.0186367512746126 0.9735398701606676 1.0767339614794431 0.9424392519486212 0.9388172780397074 1.0843070851239058 1.0 17.035471070586105 -9.738762905326482 9.844683251355468 0.999999720128775 1.0043193658646792 0.0 0.07079044048076626 0.0 0.0 0.06385727142784674 0.015487663238867577 1.8248916947524324e-10 9.738762905326482 0.004319645735904154 AQHEDQVEQYKK ddPTM_PC-9_AZD4547_30min_R2 2 AQHEDQVEQYKK 12 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ; 71.176 0.011119 27170000.0 110125.0 109831.0 142501.0 182320.0 167084.0 149299.0 127419.0 147192.0 110717.0 138122.0 False True 145142.4592577025 145331.72288773445 140611.34363150067 140288.9408159204 143887.2706797762 139963.30992836933 138759.04415668952 124446.85853567207 116569.27458676475 133286.39082106514 1.0889518304427188 1.0903718075976712 1.0549564945476628 1.052537621821091 1.0795346005950643 1.0500945300279594 1.041059355737011 0.9336801587098266 0.874577470878157 1.0 17.024169956309436 -7.707927330596965 3.402275366029683 0.9251824226028452 1.0679961079473876 0.7802319754801317 0.031603505720842175 0.09890615507023458 2.3132167117573865 0.017011275456861763 0.008532719415718568 1.959172469480913e-08 7.707927330596965 0.14281368534454242 AQHEDQVEQYKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQHEDQVEQYKK 12 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 61.48 0.022080000000000002 16116000.0 153360.0 105710.0 121190.0 171250.0 189240.0 169950.0 161380.0 157930.0 160550.0 112000.0 False True 179320.81900193106 116204.19018694818 124079.62921563454 161655.41769999074 152159.78047070638 161037.52282012394 146092.91810997867 153784.50484066692 162897.74001924065 132304.71340848762 1.355362287421177 0.8783072590027124 0.9378322662817135 1.2218417132342332 1.150070746163946 1.2171714723641363 1.1042155214751896 1.1623509161450731 1.231231570082449 1.0 17.013504933558487 -5.773764146668866 24.993131145306986 1.1622689329070275 1.039281246190293 0.09637388340627795 0.13314692956872276 404.79841676033465 820881.8625342967 0.03628310847707394 0.05425441718098139 1.6835881230297595e-06 5.773764146668866 -0.12298768671673455 AQHEDQVEQYKK ddPTM_PC-9_Lapatinib_30min_R1 1 AQHEDQVEQYKK 12 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 57.802 0.028135000000000004 18018000.0 190810.0 160090.0 172920.0 157890.0 158070.0 153830.0 141850.0 161420.0 192040.0 148190.0 False True 188089.01440973143 159719.32144090047 158703.1850905028 169501.7573056001 148772.63337757703 147251.04949524434 149194.29892261935 168920.16249268173 170410.43292914887 173804.44404923677 1.0821876013506766 0.9189599398025395 0.9131135050007355 0.975244092478914 0.8559771540446427 0.8472225799561824 0.8584032458937261 0.9718978327437279 0.9804722420151327 1.0 17.407105445690547 -4.7614458497525955 9.966748245133292 0.9182610105868813 1.0828745031229094 0.4295327710909539 0.05404689299303917 0.07217524837798266 151.06319100760197 0.014144783096629828 0.08003856217371572 1.7320249757781937e-05 4.7614458497525955 0.1646134925360282 AQIFANTVDNAR ddPTM_PC-9_Lapatinib_30min_R1 2 AQIFANTVDNAR 12 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ; 141.89 0.0003676 16591100.0 89566.0 66633.0 57987.0 70866.0 60013.0 52074.0 46503.0 38565.0 51318.0 49712.0 False True 88288.7724156072 66478.71538241942 53219.53269629308 76077.72204204598 56483.15333009764 49846.91641042294 48910.697799073496 40356.87068845419 45538.026437502864 58304.65296292373 1.5142663223079393 1.1401957134483527 0.9127836286091213 1.3048310585164489 0.9687589319160447 0.8549389092860374 0.8388815525610983 0.6921723848372335 0.7810358886187139 1.0 15.831323400859834 -1.5228787452815564 0.35895050742548346 0.8025551597909422 8.95962984207956 0.6403774843983792 0.1438405246417922 41.59015236749613 0.581080971535693 0.12372712954165228 231.5617908262796 0.029999999999915806 1.5228787452815564 8.157074682288616 AQIHDLVLVGGS(ph)TR ddPTM_PC-9_AZD4547_30min_R2 1 AQIHDLVLVGGSTR 14 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 1 AQIHDLVLVGGS(0.799)T(0.201)R 102.39 0.00083492 2124400.0 5832.3 8250.5 9457.9 10508.0 9553.9 10159.0 8225.2 11953.0 8787.3 7309.7 True False 7686.850080623818 10917.312777678906 9332.482066317923 8085.542946981642 8227.505897318186 9523.756124035033 8957.22686567625 10105.938502614868 9251.778738371499 7053.789627899519 1.0897475663606957 1.5477230472678372 1.3230451372416328 1.1462693634923955 1.16639513386908 1.3501616331689528 1.2698460456274676 1.432696328600917 1.3116040066999415 1.0 12.784182834155782 -5.539604054170553 24.804666085651245 1.2584358087303567 1.347897547601524 0.038529005007680195 0.1536720254549278 642.1166500312594 952295.1542762974 0.04081176617557024 0.07071071678591123 2.886662070622264e-06 5.539604054170553 0.08946173887116737 AQIHDLVLVGGS(ph)TR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQIHDLVLVGGSTR 14 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 1 AQIHDLVLVGGS(0.749)T(0.251)R 73.76 0.011186 1235500.0 5881.2 7781.3 6422.7 6004.1 8904.4 6978.9 7090.3 3967.6 6349.3 5148.2 True False 6876.771001005189 8553.776039179831 6575.841526225394 5667.709742554838 7159.6467407702385 6612.914198348697 6418.655454673337 3863.4547040196885 6442.146500804521 6081.527906871224 1.13076370055549 1.4065176005383997 1.0812811561376983 0.9319549016869867 1.1772776266768257 1.0873771031909736 1.0554346790748437 0.6352769835446381 1.0592973672826282 1.0 12.570218112729167 -5.9284071091740005 0.4982375900135822 0.9108685335967092 1.31302736224826 0.2941865155350779 0.15498549509543608 1.9831694422079287 0.8192624972441465 0.12431690353336126 0.41692320348196765 1.1792147173655462e-06 5.9284071091740005 0.40215882865155084 AQIHDLVLVGGSTR ddPTM_PC-9_AZD4547_30min_R2 2 AQIHDLVLVGGSTR 14 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 ; 143.64 0.00014083 21015600.0 72983.0 74869.0 80980.0 94630.0 91750.0 84819.0 69141.0 80282.0 66861.0 65673.0 False True 96190.0758592953 99068.94010690771 79906.15228860789 72814.5155189259 79012.09622028109 79515.25452155976 75294.41505613497 67876.26159683154 70395.1359605631 63373.80825930547 1.5178206660031555 1.5632473860738985 1.2608702945806463 1.1489685963165106 1.2467626357088835 1.254702166488222 1.1880998968541414 1.0710459645900317 1.1107922640932133 1.0 15.951599092126086 -1.522878745287436 0.26802105077047994 1.0463386504198635 4.838395853519874 0.8187257845572471 0.07325712059121452 22.12569889441634 0.30831776368734165 0.09308433572666833 38.713775731180746 0.029999999999509662 1.522878745287436 3.7920572031000104 AQIHDLVLVGGSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQIHDLVLVGGSTR 14 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 99.069 0.0019279 11833000.0 31359.0 33192.0 46290.0 48766.0 47056.0 41794.0 38779.0 29480.0 39033.0 32544.0 False True 36667.459331517675 36487.08240171399 47393.729155802605 46033.79912150519 37835.71459432241 39602.2490658679 35105.572384352876 28706.181236641914 39603.78378181892 38443.969581837744 0.9537896250141829 0.9490976816023635 1.2328000898791949 1.197425750312037 0.9841781430447626 1.0301290292503344 0.9131620060624009 0.7467017987186136 1.0301689501005409 1.0 15.230469690696298 -7.026088037849349 2.034617933079904 0.9023217792837462 1.0766081992872314 0.2502364361378896 0.11340435751159947 0.43137287710443734 3.5699909860404615 0.0535372467035106 0.040848050911358666 9.416986810641377e-08 7.026088037849349 0.17428642000348515 AQIHDLVLVGGSTR ddPTM_PC-9_Lapatinib_30min_R1 1 AQIHDLVLVGGSTR 14 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 137.73 6.357e-05 15978000.0 53525.0 47383.0 52385.0 37597.0 62390.0 55797.0 47893.0 44532.0 46245.0 40601.0 False True 52761.72368471718 47273.28757470282 48078.107511947695 40362.00879991533 58720.34286345941 53410.692379159795 50372.66519775125 46601.119292058684 41036.40111856116 47618.82875256812 1.1080012899702347 0.9927436019130004 1.0096448982768145 0.8476060805619579 1.233132867853088 1.1216296951923521 1.0578308311506845 0.9786280030994137 0.8617683843462453 1.0 15.539244515620899 -7.932502033817968 4.16776250336212 0.9271912914596325 1.0502253629994498 0.2031695536398932 0.0988535709586219 0.3510322439095603 11.931660275577421 0.0630180047197318 0.027551073811190888 1.168148259364734e-08 7.932502033817968 0.12303407153981727 AQIPEGDY(ph)LSYR ddPTM_PC-9_AZD4547_30min_R2 2 AQIPEGDYLSYR 12 0 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 AQIPEGDY(0.993)LS(0.007)YR;AQIPEGDY(1)LSYR 137.01 9.440200000000001e-05 12230500.0 26081.0 61258.0 55003.0 63854.0 62631.0 39799.0 48167.0 59040.0 48606.0 37897.0 True False 34374.21548149954 81058.45053451949 54273.62428167825 49133.446834465714 53935.76673975395 37310.36223845557 52453.76968815686 49916.7246042317 51175.213928884325 36570.237564949035 0.9399505655507612 2.216514191097584 1.4840927457823552 1.343536441271521 1.474854152750952 1.0202384431381413 1.434329476121082 1.364954890314267 1.3993678284970594 1.0 15.158382378191012 -5.628380162722797 4.389008553365371 1.3093598179733017 1.6361747832597722 0.10870260819919497 0.32573697681125835 0.37830072725663494 12.726442101778002 0.0844013937376357 0.1518022827063956 2.3529886769915526e-06 5.628380162722797 0.32681496528647047 AQIPEGDY(ph)LSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AQIPEGDYLSYR 12 0 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 AQIPEGDY(0.754)LS(0.222)Y(0.024)R;AQIPEGDY(0.979)LS(0.021)YR 158.56 0.0006963999999999999 9113100.0 40455.0 35529.0 55954.0 29375.0 92124.0 36896.0 39210.0 33170.0 36781.0 30801.0 True False 47303.232477328565 39056.084317019064 57288.15556672667 27729.213985034938 74072.9635176674 34961.10880830411 35495.74494418313 32299.3226465201 37318.852542184344 36384.977479418165 1.3000759036909262 1.073412353741647 1.574500234310514 0.762106119227928 2.035811718162204 0.9608665781937205 0.9755604483818068 0.8877103926968434 1.0256665010523764 1.0 15.15105529729612 -6.9121753889196205 24.99806955965579 0.9630075472046636 1.3322214230340717 0.27195472940697896 0.309503982088644 29.208671654543668 8307.393676538859 0.10297362678661544 0.09081419875911516 1.2241217404200322e-07 6.9121753889196205 0.369213875829408 AQIPEGDY(ph)LSYR ddPTM_PC-9_Lapatinib_30min_R1 4 AQIPEGDYLSYR 12 0 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 AQIPEGDY(0.996)LS(0.004)YR;AQIPEGDY(0.997)LS(0.002)YR;AQIPEGDY(0.876)LS(0.124)YR;AQIPEGDY(0.981)LS(0.018)YR 144.7 0.00010206 14280100.0 136374.0 145794.0 73615.0 31722.9 68893.0 50693.8 47994.7 42619.4 87948.0 27588.9 True False 134429.2817520715 145456.42295055662 67562.65886211762 34055.907890492184 64840.84918884934 48525.74434701958 50479.63072612933 44599.65291376909 78042.37010650258 32357.604605101515 4.154488052891199 4.495277840425304 2.0879993957113148 1.0524854452644778 2.0038828578375822 1.499670477442233 1.5600546252478371 1.3783360498427466 2.4118710596456943 1.0 14.981817190276143 -5.328168666507618 4.147886469518097 1.5914113752144061 4.346784513512279 0.8767180035538937 0.4080115080027118 0.060282247578597827 2.037185690281154 0.10181772233444357 0.2353872850492355 4.6971165173925625e-06 5.328168666507618 2.7553731382978732 AQIS(ph)SPNLR ddPTM_PC-9_AZD4547_30min_R2 2 AQISSPNLR 9 0 H0Y507;Q5TCZ1-2;Q5TCZ1-3;Q5TCZ1 H0Y507 SH3PXD2A SH3 and PX domain-containing protein 2A 1 AQIS(0.5)S(0.5)PNLR;AQIS(0.5)S(0.5)PNLR 141.91 0.0006911 26232000.0 84489.0 104355.0 147413.0 198428.0 175202.0 146444.0 118103.0 165376.0 121351.0 147008.0 True False 111354.74451962809 138085.71297675074 145458.207302057 152683.49028203965 150878.22650665618 137286.8335296964 128613.93820417287 139820.9391624223 127765.36611702344 141861.29466575244 0.7849550843448695 0.9733853994643319 1.0253551375290875 1.0762871623425263 1.0635616068649947 0.9677539871123113 0.906617541502124 0.985617250229264 0.9006358388174786 1.0 17.114121493639686 -10.354091150014474 14.878774598442055 0.999999867619853 0.9720905576458808 0.009565858164058416 0.08165576077086022 0.0 0.0 0.08300384344060577 0.020131389049285252 4.4249549136821445e-11 10.354091150014474 -0.02790930997397223 AQIS(ph)SPNLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AQISSPNLR 9 0 H0Y507;Q5TCZ1-2;Q5TCZ1-3;Q5TCZ1 H0Y507 SH3PXD2A SH3 and PX domain-containing protein 2A 1 AQIS(0.5)S(0.5)PNLR;AQIS(0.5)S(0.5)PNLR;AQIS(0.5)S(0.5)PNLR;AQIS(0.5)S(0.5)PNLR 132.32 0.0012054000000000001 30530200.0 196522.0 222010.0 275671.0 276299.0 316077.0 284037.0 281569.0 267736.0 250850.0 212593.0 True False 229789.29311357177 244049.68558702435 282244.04212809005 260818.8628034441 254143.98082772997 269141.59970143874 254896.74593697308 260708.2136897409 254518.20668842504 251134.42801473784 0.9150051425847776 0.9717890434867109 1.1238763412857378 1.0385627524878345 1.01198383207266 1.0717033177372404 1.0149812909045448 1.0381221553360307 1.0134739736818905 1.0 17.93810029564441 -5.020561480918313 9.62251724557601 1.0403311226247 0.9289101811197907 0.573115451432815 0.03458310903791391 0.20388382819069734 95.51555137570139 0.008568426459710737 0.024818358198709096 9.5375871438783e-06 5.020561480918313 -0.11142094150490933 AQIS(ph)SPNLR ddPTM_PC-9_Lapatinib_30min_R1 2 AQISSPNLR 9 0 H0Y507;Q5TCZ1-2;Q5TCZ1-3;Q5TCZ1 H0Y507 SH3PXD2A SH3 and PX domain-containing protein 2A 1 AQIS(0.5)S(0.5)PNLR;AQIS(0.5)S(0.5)PNLR 108.43 0.002436 16047800.0 116170.0 93904.0 112486.0 89438.0 88239.0 84538.0 80942.0 84952.0 92292.0 67581.0 True False 114513.39449703098 93686.57105744458 103237.835288517 96015.56887642165 83048.95550454872 80922.50680770313 85132.78070775227 88899.18005252337 81897.10308215472 79262.28580397797 1.4447399962730303 1.1819816966815597 1.3024837000516551 1.211365126585876 1.0477739149478416 1.0209459137707815 1.0740641636085606 1.121582340842128 1.0332417523851491 1.0 16.274346952589795 -6.088235216463841 2.666742710347612 1.0545145785898031 1.2974288847803936 0.7552155077589173 0.06717420903565971 0.14303095791393874 1.991198112649224 0.02049407710098126 0.028976276519192667 8.161402252547123e-07 6.088235216463841 0.2429143061905905 AQISS(ph)PNLR ddPTM_PC-9_Lapatinib_30min_R1 1 AQISSPNLR 9 0 H0Y507;Q5TCZ1-2;Q5TCZ1-3;Q5TCZ1 H0Y507 SH3PXD2A SH3 and PX domain-containing protein 2A 1 AQIS(0.213)S(0.787)PNLR 78.513 0.021493 3644100.0 44573.0 31638.0 38269.0 34997.0 32992.0 31786.0 33828.0 28062.0 35341.0 27342.0 True False 43937.38084631292 31564.744154832923 35122.670542611944 37570.79612656962 31051.47542476767 30426.586876785008 35579.44831832477 29365.862965367618 31360.524422771523 32068.0282690751 1.370130413932685 0.9843057356062168 1.0952550698753936 1.1715967009671477 0.9683001138773553 0.948813772442847 1.1094990942313694 0.9157364687022768 0.9779374073027789 1.0 14.96884803068239 -4.757593870626187 24.99823371514867 1.022610435107124 1.3701309127238093 0.6532785890815231 0.07669131434720335 73.70781235955224 479079.59438476263 0.01995453264980701 0.14606211098051602 1.747455517640328e-05 4.757593870626187 0.34752047761668536 AQKLPDLS(ph)PVENK ddPTM_PC-9_AZD4547_30min_R2 1 AQKLPDLSPVENK 13 1 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3;H7C5N8;A0A2R8Y7F4;A0A2R8YET2 E7EPN9 PRRC2C Protein PRRC2C 1 AQKLPDLS(1)PVENK 75.445 0.008659299999999998 7245800.0 50443.0 35355.0 68323.0 93873.0 92807.0 67714.0 46300.0 54658.0 56742.0 75358.0 True False 66482.82472042029 46782.81234529271 67416.99237854492 72232.0301733924 79922.35001542936 63479.832875569184 50420.610305015136 46211.862015889186 59741.26627891112 72719.73935719016 0.9142335397252329 0.6433303083706262 0.9270796756765199 0.9932933040174663 1.0990461561318432 0.8729381243208845 0.693355212088364 0.6354789280652171 0.8215275083078829 1.0 16.150059408168886 -7.093490498468994 6.32873023973483 0.7588487275483253 0.9128011463934569 0.14437103830674403 0.13989402889515556 0.4148298681393883 23.379650476114794 0.0566639100423924 0.043913287477407345 8.063238419822231e-08 7.093490498468994 0.15395241884513156 AQLDYVDLYLIHSPMSLKPGEELS(ph)PTDENGK ddPTM_PC-9_AZD4547_30min_R2 1 AQLDYVDLYLIHSPMSLKPGEELSPTDENGK 31 1 A0A0A0MSS8;P42330;S4R3Z2;S4R3D5 A0A0A0MSS8 AKR1C3 Aldo-keto reductase family 1 member C3 1 AQLDYVDLYLIHS(0.003)PMS(0.131)LKPGEELS(0.433)PT(0.433)DENGK 62.052 0.00024333 7356200.0 11684.0 10222.0 12678.0 17909.0 16510.0 16750.0 14600.0 17129.0 14689.0 15908.0 True False 15399.268957702572 13526.061597895134 12509.881436341959 13780.356741291791 14217.871483344305 15702.619852110123 15899.37171605228 14482.106635262287 15465.430551812162 15351.065762018347 1.0031400553180803 0.8811154748200842 0.8149194088721804 0.8976807835314725 0.926181393771513 1.0229009565551854 1.0357177776796809 0.943394215084008 1.0074499576489846 1.0 13.906051199066976 -6.603593211785186 4.04592579601369 1.0001661682468077 0.8935738437211674 0.5045081172880209 0.04852446372154859 0.19145890972745078 6.044407762327252 0.017274689809944933 0.01738648418054378 2.4911896346552427e-07 6.603593211785186 -0.10659232452564027 AQLDYVDLYLIHSPMSLKPGEELS(ph)PTDENGK ddPTM_PC-9_Lapatinib_30min_R1 1 AQLDYVDLYLIHSPMSLKPGEELSPTDENGK 31 1 A0A0A0MSS8;P42330;S4R3Z2;S4R3D5 A0A0A0MSS8 AKR1C3 Aldo-keto reductase family 1 member C3 1 AQLDYVDLYLIHS(0.065)PMS(0.138)LKPGEELS(0.398)PT(0.398)DENGK 58.711999999999996 0.00053772 1519000.0 829.28 2434.8 4175.0 997.17 4326.8 4233.5 2967.6 3384.5 3929.2 4411.1 True False 817.4543151286728 2429.1623701936674 3831.7476159660546 1070.5052082616055 4072.306130816098 4052.443073770508 3121.2478074216815 3541.7562257247046 3486.6521196897056 5173.552757578714 0.1580063746196823 0.4695346667984005 0.7406414499886843 0.20691877679094456 0.7871391907332144 0.7832998451275291 0.6033083943812847 0.6845887906596492 0.6739376755329546 1.0 12.33693962621624 -5.611414805323167 0.20045641173370488 0.9781821266825708 1.8199348627509942e-23 0.5088473097663143 0.1754539669889653 9.625773779355631 0.5134227739815069 0.4530164574889917 2.4304664999411925 2.4467251981483065e-06 5.611414805323167 -0.9781821266825708 AQLDYVDLYLIHSPMSLKPGEELSPT(ph)DENGK ddPTM_PC-9_AZD4547_30min_R2 1 AQLDYVDLYLIHSPMSLKPGEELSPTDENGK 31 1 A0A0A0MSS8;P42330;S4R3Z2;S4R3D5 A0A0A0MSS8 AKR1C3 Aldo-keto reductase family 1 member C3 1 AQLDYVDLYLIHSPMS(0.014)LKPGEELS(0.418)PT(0.568)DENGK 110.08 1.2974e-15 2524600.0 9383.0 9520.8 12923.0 11522.0 11350.0 15214.0 15021.0 14961.0 14165.0 14642.0 True False 12366.59882147579 12598.212410608478 12751.6325762618 8865.78091312547 9774.248415260925 14262.666174925575 16357.83990046722 12649.121219578426 14913.732981579362 14129.388036677938 0.8752395212994228 0.8916318511392892 0.9024900825966649 0.6274709768116729 0.6917672860203378 1.0094326900713368 1.1577175075102 0.8952348952936289 1.0555116005636884 1.0 13.786411361458459 -6.829641509965999 8.45033116656148 1.026511170233423 0.7995371547400033 0.5550974018761343 0.1011105794332145 0.23391872238996925 26.06781695565054 0.038586819820603246 0.03408022238668699 1.4803298278717496e-07 6.829641509965999 -0.22697401549341978 AQLEPVAS(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 3 AQLEPVASPAK 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 AQLEPVAS(1)PAK;AQLEPVAS(1)PAK;AQLEPVAS(1)PAK 147.73 9.3249e-05 655020000.0 2734060.0 2124200.0 2282870.0 2081030.0 2379530.0 2503260.0 3074550.0 2871370.0 2791500.0 2521310.0 True False 3603434.2080191947 2810806.1090049706 2252597.6521992427 1601280.6850929947 2049173.3331776066 2346730.7564772004 3348178.993807439 2427665.744018515 2939052.991039799 2433039.70432704 1.4810420896998377 1.1552652034432862 0.9258367827672972 0.6581399729092775 0.8422276584854961 0.9645262887833917 1.3761300269177152 0.9977912566330227 1.2079757620941574 1.0 21.214328432867404 -4.848724763883909 2.9144103347515777 0.992650105828728 1.527621136411868 0.3932901925470663 0.18295074466328146 0.3884242322855087 5.1699694256781115 0.0522875941067678 0.4593015901275008 1.416691330129808e-05 4.848724763883909 0.5349710305831399 AQLEPVAS(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 AQLEPVASPAK 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 AQLEPVAS(1)PAK;AQLEPVAS(1)PAK;AQLEPVAS(1)PAK;AQLEPVAS(1)PAK;AQLEPVAS(1)PAK;AQLEPVAS(1)PAK 147.73 0.00016476 915852000.0 3609160.0 4114580.0 3505853.0 3396758.0 3637470.0 2653128.0 3309624.0 2846181.0 2482967.0 2517247.0 True False 4220119.503840691 4523048.310088093 3589445.831541548 3206448.661698022 2924733.865296877 2513993.2971150912 2996112.4551172405 2771471.764528048 2519275.6950629433 2973603.954583714 1.4191935336027228 1.5210661470623759 1.2071028577993832 1.0783038732361738 0.9835653671325312 0.8454364923882525 1.0075694345572923 0.9320245085953409 0.8472129219426016 1.0 21.50378108127198 -5.627253757306667 1.430634320865125 0.9296900321793758 1.4948248950031013 0.9130397546527066 0.06444751688905019 0.11284184658014063 0.447974147666931 0.02025596489775514 0.05762051641409641 2.3590994138216633e-06 5.627253757306667 0.5651348628237255 AQLEPVAS(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 5 AQLEPVASPAK 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 AQLEPVAS(1)PAK;AQLEPVAS(1)PAK;AQLEPVAS(1)PAK;AQLEPVAS(1)PAK;AQLEPVAS(1)PAK 166.48 7.152500000000001e-18 939110000.0 1056494.0 1606873.0 1648503.0 1741501.0 1705467.0 1546204.0 1523450.0 1435628.0 1634834.0 1358082.0 True False 1041428.2018227283 1603152.3842944792 1512969.4467455994 1869576.7930170312 1605154.784137132 1480076.459297567 1602326.7867019002 1502332.5178976818 1450701.7793547804 1592824.664169484 0.6538247587757816 1.006483902690181 0.9498656573945494 1.1737492738987996 1.0077410403323188 0.9292149303007526 1.0059655797315084 0.9431876286778961 0.9107730511639157 1.0 20.60315603514836 -4.760105894811481 24.994182210175563 0.9934583719726408 0.6538243467940607 0.6796572425467151 0.06961986421125654 20.54454201441942 384931.28222082113 0.018114475847631584 0.1098907825741586 1.737377149275703e-05 4.760105894811481 -0.3396340251785801 AQLEPVAS(ph)PAKKPK ddPTM_PC-9_AZD4547_30min_R2 2 AQLEPVASPAKKPK 14 2 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 AQLEPVAS(1)PAKKPK;AQLEPVAS(1)PAKKPK 90.714 0.013561000000000002 82860000.0 178959.0 58906.0 178835.0 338670.0 294910.0 177223.0 157074.0 179655.0 167447.0 197601.0 True False 235864.23942155915 77946.21253038647 176463.53105128676 260594.86389934065 253966.83701714507 166141.21779406088 171053.28170734228 151893.44781120028 176297.90657017418 190683.04913506334 1.236943926014595 0.40877368430990496 0.9254285152860928 1.3666388547980364 1.3318794626430428 0.8712951599404143 0.8970555195295989 0.7965755136609555 0.9245599300507306 1.0 17.540817074690956 -10.403308918357435 7.049879344701998 0.9999999998586248 0.9669146590807469 0.0003929120277290643 0.26906685579150263 1.7765836672832445e-09 2.912949906813625e-10 0.27562875589915503 0.06684979159384889 3.950854915161646e-11 10.403308918357435 -0.033085340777877836 AQLEPVAS(ph)PAKKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQLEPVASPAKKPK 14 2 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 AQLEPVAS(1)PAKKPK 43.761 0.045512000000000004 36512000.0 116730.0 28910.0 59156.0 105300.0 100940.0 187050.0 125690.0 171030.0 145400.0 127800.0 True False 136490.08347740836 31779.993740466107 60566.50339037928 99400.3823872063 81161.53160385304 177240.7687172941 113783.73328320247 166540.64372126403 147526.1999302249 150969.1283357566 0.9040926776357434 0.21050657237542722 0.40118469291071795 0.6584152898209693 0.5376034987984373 1.1740199514374168 0.7536887477428266 1.1031437059825653 0.9771944870882833 1.0 17.203894037560516 -6.745851123503308 24.819382921785397 0.9925607848246114 0.5225284282474395 0.5807863268094128 0.1946466242248823 154.25786732121716 245606.50452703334 0.06279944204854766 0.06258256606588362 1.7953489684229146e-07 6.745851123503308 -0.4700323565771719 AQLEPVAS(ph)PAKKPK ddPTM_PC-9_Lapatinib_30min_R1 2 AQLEPVASPAKKPK 14 2 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 AQLEPVAS(1)PAKKPK;AQLEPVAS(1)PAKKPK 84.829 0.020055 81154000.0 663090.0 192511.0 218016.0 223097.0 139046.0 183145.0 81354.0 82615.0 237732.0 116663.0 True False 653634.2150041874 192065.25260734028 200091.56604609665 239504.29760977492 130867.58765495388 175312.31528184703 85566.11205182075 86453.59450088556 210956.1187310583 136828.04410632412 4.777048588783978 1.4036980054914279 1.4623578620374982 1.7504035753347815 0.9564383420789193 1.2812601132090888 0.6253550769557915 0.631841192100251 1.5417608291406397 1.0 17.062004427954584 -4.756699214884105 4.484939131603142 1.1575678776379266 5.102865199644756 0.9044168021359733 0.351248957852347 0.06436557728992946 2.817635042646257 0.09534306488436804 0.8291210530596127 1.7510590230336858e-05 4.756699214884105 3.9452973220068297 up AQLGEDIR ddPTM_PC-9_Lapatinib_30min_R1 2 AQLGEDIR 8 0 Q92734-4;Q92734-3;Q92734-2;Q92734;C9JTY3;C9JUE0;C9JJP5 Q92734-4 TFG Protein TFG 0 ; 113.71 0.0070375 4500000.0 78771.0 78679.0 85791.0 72117.0 92515.0 90063.0 81387.0 78162.0 79782.0 64965.0 False True 77647.71109516763 78496.82360952339 78737.59514283676 77420.72475525952 87073.44959148821 86211.2154371072 85600.82063035063 81793.69186440947 70796.1110182948 76194.11368957882 1.0190775551443632 1.0302216248531482 1.03338160036378 1.016098501659564 1.142784466871453 1.1314681838591742 1.1234571344854212 1.073490954926568 0.9291545972530643 1.0 16.21739192741408 AQLGGPEAAK ddPTM_PC-9_Lapatinib_30min_R1 1 AQLGGPEAAK 10 0 P04792;C9J3N8 P04792 HSPB1 Heat shock protein beta-1 0 112.71 0.0065051 13533000.0 44875.0 45475.0 50047.0 48477.0 44551.0 35021.0 44316.0 39227.0 31324.0 36609.0 False True 44235.07427093287 45369.70543147567 45932.328847006735 52042.160294531364 41930.59777063602 33523.23346793835 46610.465640146664 41049.62962520404 27795.9612636568 42936.81687157377 1.0302364612458872 1.0566620615398388 1.0697655810022595 1.212063773851521 0.9765651211651902 0.7807573059784116 1.085559411158982 0.9560473415620351 0.6473689315813967 1.0 15.389927620261373 -6.516021137704423 24.610153140358097 0.9004515527238351 1.0888275241323953 0.3741970812741454 0.12069021945851781 296.00374008034305 1062284.964583959 0.039083112148902734 0.04057427199590819 3.0477466480342597e-07 6.516021137704423 0.1883759714085601 AQLGGPEAAKS(ph)DETAAK ddPTM_PC-9_Lapatinib_30min_R1 1 AQLGGPEAAKSDETAAK 17 1 P04792;C9J3N8 P04792 HSPB1 Heat shock protein beta-1 1 AQLGGPEAAKS(0.921)DET(0.079)AAK 70.538 0.006882300000000001 11662000.0 27709.0 22352.0 23037.0 25900.0 29966.0 21854.0 29718.0 23341.0 24541.0 20357.0 True False 27313.86457879173 22300.245317302797 21142.98678539161 27804.7723998672 28203.45879542273 20919.355364162195 31256.652628709235 24425.508070509764 21776.93415181336 23875.680326002537 1.144003613963818 0.9340150736151395 0.8855448932429036 1.1645646122002047 1.1812630429930366 0.876178399045632 1.3091418632652836 1.0230287781122793 0.9120969059087513 1.0 14.54325422218333 -4.442091834686649 16.411469061073426 1.040447502619806 3.3372045082171073 0.05361658059568264 0.1371681596353432 2781848.2020407678 8479862.649511192 0.03429369718541763 227094289.0528573 3.6133344800855126e-05 4.442091834686649 2.2967570055973017 AQLGGPEAAKSDET(ph)AAK ddPTM_PC-9_Lapatinib_30min_R1 1 AQLGGPEAAKSDETAAK 17 1 P04792;C9J3N8 P04792 HSPB1 Heat shock protein beta-1 1 AQLGGPEAAKS(0.268)DET(0.732)AAK 56.773999999999994 0.03443 11350000.0 23704.0 19861.0 17569.0 18418.0 25142.0 20896.0 23323.0 18991.0 17618.0 21816.0 True False 23365.976613218776 19815.0130747562 16124.544638301226 19772.52116064688 23663.19699107385 20002.326790955143 24530.55081968454 19873.39119005403 15633.675314235268 25586.866532007254 0.9132019578868592 0.7744212465394738 0.6301883279896985 0.7727605541660577 0.9248180882748173 0.7817419442874621 0.9587164879684918 0.7767028121709981 0.6110039029077168 1.0 14.643115859653257 -4.753938604981481 24.035988781504134 0.7979996336876797 0.9132022962794965 0.06691672834121531 0.12155485941677349 491.6983663219406 1575410.6254273013 0.030299223102845715 0.3020513498695105 1.7622251497347875e-05 4.753938604981481 0.11520266259181677 AQLS(ph)PGIYDDTSAR ddPTM_PC-9_AZD4547_30min_R2 3 AQLSPGIYDDTSAR 14 0 O75376-2;O75376;A0A088AWL3;E7EVK1 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 AQLS(1)PGIYDDTSAR;AQLS(1)PGIYDDTSAR;AQLS(0.886)PGIYDDT(0.057)S(0.057)AR 168.68 0.00018137 308660100.0 59833.0 60327.0 96014.0 140449.0 102486.0 78923.0 66110.0 109022.0 80250.0 76264.0 True False 78858.64939628699 79826.52299121695 94740.79162556681 108070.6529654191 88257.58793713042 73987.9323336171 71993.6619279602 92175.1549763304 84491.85116637789 73594.02057295485 1.071536094676513 1.0846876195883839 1.2873436032978909 1.4684705649188856 1.199249439696522 1.0053524968142182 0.9782542299967402 1.2524815774259241 1.1480803808322968 1.0 16.167300933329265 -6.589550000081503 8.036458283560687 1.0874620029146507 1.235749087004031 0.2433739006430763 0.12800529763839952 0.42878884639719345 45.49692108240293 0.046796708681656314 0.04679681673586839 2.573060512350935e-07 6.589550000081503 0.1482870840893804 AQLS(ph)PGIYDDTSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AQLSPGIYDDTSAR 14 0 O75376-2;O75376;A0A088AWL3;E7EVK1 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 AQLS(1)PGIYDDTSAR;AQLS(0.938)PGIYDDT(0.05)S(0.011)AR 170.09 1.3826e-05 47920000.0 38503.0 35636.0 56455.0 45949.0 50944.0 42435.0 47805.0 39870.0 41147.0 30137.0 True False 45020.79743108595 39173.7065698807 57801.1013067798 43374.62649866792 40961.88890456395 40209.63389745192 43276.56432177186 38823.454745756906 41748.697032523836 35600.599535639274 1.2646078442026305 1.100366484858336 1.6235990983499 1.218367866396356 1.1505954798193094 1.129465077047329 1.2156133572539496 1.090528116159709 1.1726964595281544 1.0 15.119613916803214 -5.994527595071862 24.995658258828783 1.1400574916588682 1.3256711220178947 0.32197379178320074 0.1312701344569486 189.16798255428637 864025.9738869099 0.03666602300369547 0.05419337140394359 1.0126804010564183e-06 5.994527595071862 0.18561363035902656 AQLS(ph)PGIYDDTSAR ddPTM_PC-9_Lapatinib_30min_R1 3 AQLSPGIYDDTSAR 14 0 O75376-2;O75376;A0A088AWL3;E7EVK1 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 AQLS(1)PGIYDDTSAR;AQLS(0.997)PGIY(0.002)DDT(0.001)SAR;AQLS(0.993)PGIY(0.003)DDT(0.002)S(0.002)AR 193.3 1.6617e-07 246915400.0 109927.0 109613.0 142536.0 98417.0 109589.0 117657.0 113739.0 108535.0 129064.0 102103.0 True False 108359.42082185711 109359.19783310268 130817.24028487138 105654.91448948775 103143.19048026383 112625.08438186305 119627.84889079884 113577.93232649752 114527.45321582827 119751.36750630442 0.904870007569245 0.9132187807988528 1.0924070681529745 0.8822856614470432 0.8613111702029939 0.9404910083881406 0.9989685410857702 0.9484478940962249 0.9563769967787538 1.0 16.869682605415377 -7.0259184458212385 22.86347106243295 0.9713777219692509 0.9325996062948563 0.10992678442460013 0.060520899643390455 746.5374616704676 658541.0188988304 0.024371691582816248 0.01897382554967761 9.420664862797995e-08 7.0259184458212385 -0.0387781156743946 AQLYLPS(ph)TSPPHEGLDGFAQELSR ddPTM_PC-9_AZD4547_30min_R2 1 AQLYLPSTSPPHEGLDGFAQELSR 24 0 I3L465;I3L1Z8;I3L1A6;Q8N137-4;Q8N137-5;Q8N137;Q8N137-3;Q8N137-2 I3L465 CNTROB Centrobin 1 AQLY(0.009)LPS(0.447)T(0.317)S(0.227)PPHEGLDGFAQELSR 67.895 0.00057973 16664000.0 3785.8 2823.6 6770.5 10858.0 8316.5 5548.0 5385.4 7369.6 6268.3 7541.7 True False 4989.605650468194 3736.273481492533 6680.718746233884 8354.855854427731 7161.8975282394285 5201.082682955641 5864.690167097805 6230.7976565607405 6599.62954101192 7277.667378514827 0.6856050697231008 0.5133888768429815 0.9179752795458531 1.1480128755393502 0.9840924510211645 0.7146634233807261 0.8058475143301518 0.8561531233146679 0.9068330823273657 1.0 12.829260399824477 -5.270584982782401 24.679614854293526 0.9110536787932196 0.599496972096673 0.5399574762624533 0.11702232951089629 404.7962552994454 1092354.1838765235 0.03384103479507467 0.07209411757867235 5.363089161959337e-06 5.270584982782401 -0.31155670669654667 AQLYLPS(ph)TSPPHEGLDGFAQELSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AQLYLPSTSPPHEGLDGFAQELSR 24 0 I3L465;I3L1Z8;I3L1A6;Q8N137-4;Q8N137-5;Q8N137;Q8N137-3;Q8N137-2 I3L465 CNTROB Centrobin 1 AQLY(0.009)LPS(0.411)T(0.29)S(0.29)PPHEGLDGFAQELSR;AQLY(0.019)LPS(0.751)T(0.115)S(0.115)PPHEGLDGFAQELSR;AQLYLPS(0.388)T(0.306)S(0.306)PPHEGLDGFAQELSR 93.667 4.0596e-06 32208400.0 22381.4 26026.8 37389.2 39523.0 41030.0 37375.1 35229.0 37322.0 34072.5 24935.6 True False 26170.128967200162 28610.56869887108 38280.70032733064 37308.654445294844 32990.46603631944 35415.083960896765 31891.854084127193 36342.33704592773 34570.74585366293 29456.226889898997 0.8884413154820691 0.9712910212774771 1.299579218696801 1.2665795447850983 1.1199827513425487 1.202295327683029 1.0826863265051578 1.233774345294376 1.173631164061877 1.0 14.84628502391344 -5.097978799058173 5.305889430957371 1.179418934642014 0.9068329928976795 0.5746034246023229 0.08446428144129009 0.13306804695187843 5.5700442247185205 0.021034659959253497 0.06004143009515543 7.980336439036315e-06 5.097978799058173 -0.2725859417443346 AQLYLPS(ph)TSPPHEGLDGFAQELSR ddPTM_PC-9_Lapatinib_30min_R1 1 AQLYLPSTSPPHEGLDGFAQELSR 24 0 I3L465;I3L1Z8;I3L1A6;Q8N137-4;Q8N137-5;Q8N137;Q8N137-3;Q8N137-2 I3L465 CNTROB Centrobin 1 AQLY(0.008)LPS(0.527)T(0.123)S(0.342)PPHEGLDGFAQELSR 89.631 8.0676e-06 9249400.0 13469.0 10286.0 13793.0 12067.0 14213.0 13472.0 12239.0 11890.0 16949.0 9478.4 True False 13276.929590087906 10262.18339896996 12658.992782519703 12954.447434331949 13377.019283833128 12895.833964765858 12872.675534113074 12442.452806579036 15040.025139117586 11116.728810825885 1.1943198233960999 0.9231297779771567 1.138733614711542 1.165311095986836 1.2033233437165516 1.1600385494883543 1.157955343983671 1.1192548651957859 1.3529182365653327 1.0 13.440444705139479 -5.5040278040945125 23.534491682333464 1.1700392978806426 1.0517764958679636 0.1451476351114217 0.1015785048138282 537.91753372725 671560.908274634 0.024737630922403546 0.050018896473143025 3.1330851337315598e-06 5.5040278040945125 -0.11826280201267902 AQLYLPSTS(ph)PPHEGLDGFAQELSR ddPTM_PC-9_AZD4547_30min_R2 2 AQLYLPSTSPPHEGLDGFAQELSR 24 0 I3L465;I3L1Z8;I3L1A6;Q8N137-4;Q8N137-5;Q8N137;Q8N137-3;Q8N137-2 I3L465 CNTROB Centrobin 1 AQLY(0.001)LPS(0.261)T(0.188)S(0.55)PPHEGLDGFAQELSR;AQLY(0.003)LPS(0.22)T(0.261)S(0.516)PPHEGLDGFAQELSR 93.416 4.3086000000000006e-06 18840600.0 25648.7 19654.9 38115.0 61858.0 54282.0 45560.0 31565.0 48637.0 37289.0 44250.0 True False 33804.45307389815 26007.962052481802 37609.57019610143 47597.59379657312 46745.88127552365 42711.12599773956 34374.223850492504 41121.269217073495 39260.0204129977 42700.82096865174 0.7916581533342241 0.6090740520322833 0.8807692532120639 1.1146763157438189 1.0947302701707198 1.0002413309358944 0.8050014746959526 0.9630088669082534 0.9194207399857708 1.0 15.381976187006849 -5.471152925091939 5.514625045441665 0.9828748078696833 0.7060584407508311 0.6039826746307064 0.09140722576743805 0.14464684908858974 9.919309431322048 0.026269640662607414 0.05451294088316213 3.379458167451159e-06 5.471152925091939 -0.27681636711885216 AQLYLPSTS(ph)PPHEGLDGFAQELSR ddPTM_PC-9_Lapatinib_30min_R1 1 AQLYLPSTSPPHEGLDGFAQELSR 24 0 I3L465;I3L1Z8;I3L1A6;Q8N137-4;Q8N137-5;Q8N137;Q8N137-3;Q8N137-2 I3L465 CNTROB Centrobin 1 AQLY(0.001)LPS(0.186)T(0.137)S(0.676)PPHEGLDGFAQELSR 94.449 3.7035e-06 13544000.0 15241.0 8344.5 17292.0 12851.0 16280.0 14865.0 11430.0 12614.0 18208.0 11552.0 True False 15023.660545142902 8325.17882293455 15870.318509050308 13796.105409679281 15322.442407711482 14229.258602007472 12021.78947258048 13200.092489670986 16157.223301259839 13548.747807927557 1.1088597085224623 0.6144611251870357 1.1713494659458026 1.0182568607267892 1.1309120684013405 1.0502268404229753 0.8872989329350692 0.9742666021097117 1.1925252082562219 1.0 13.725871901625164 -5.2892373079272055 24.999718531666844 1.0476953212213163 0.8616601503458815 0.22631431945170755 0.1413056175231683 906.9868388188004 815685.7751722779 0.03520802162454309 0.07331536365176253 5.1376284370544425e-06 5.2892373079272055 -0.18603517087543475 AQNEATST(ph)PHR ddPTM_PC-9_AZD4547_30min_R2 2 AQNEATSTPHR 11 0 Q13415 Q13415 ORC1 Origin recognition complex subunit 1 1 AQNEAT(0.001)S(0.19)T(0.809)PHR;AQNEATST(1)PHR 138.21 0.00020782 28596000.0 46501.0 29354.0 52993.0 71942.0 64692.0 57949.0 43373.0 66863.0 42364.0 54266.0 True False 61287.350719113914 38842.106451243766 52290.27819498892 55356.883392820084 55710.632465203504 54325.439869249516 47233.1129753655 56530.859708888 44603.27455217987 52366.163857284904 1.1703616649510968 0.7417405360664061 0.9985508645906773 1.0571116789017787 1.0638669774825091 1.0374149234475964 0.9019777179800936 1.0795302833897336 0.8517575332372738 1.0 15.676347301946413 AQNEATST(ph)PHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 AQNEATSTPHR 11 0 Q13415 Q13415 ORC1 Origin recognition complex subunit 1 1 AQNEATS(0.178)T(0.822)PHR;AQNEATS(0.024)T(0.976)PHR;AQNEATS(0.01)T(0.99)PHR;AQNEATS(0.035)T(0.965)PHR;AQNEAT(0.001)S(0.204)T(0.795)PHR 126.56 0.00084798 32957200.0 54182.5 51401.50000000001 71726.6 72711.5 81628.8 67050.8 60411.299999999996 77757.0 62328.4 50192.9 True False 63354.52709684476 56504.30121932098 73436.8341686453 68637.71038886363 65634.2226172439 63534.53801181256 54688.70432406345 75715.96114035154 63239.834936251995 59292.475443222225 1.0685087209339457 0.9529759180560581 1.2385523393936817 1.157612494263126 1.106957031674187 1.0715447033857186 0.9223548842455179 1.2769910612495214 1.0665743749695475 1.0 15.855561409623583 -8.535877935202995 23.643984721013258 0.999999985570069 1.0993766906550992 0.0780600227603333 0.10433741106328631 2992.738639500894 5443438.473685307 0.10120500558828414 0.026131020266479076 2.9115353325367737e-09 8.535877935202995 0.09937670508503027 AQNEATST(ph)PHR ddPTM_PC-9_Lapatinib_30min_R1 3 AQNEATSTPHR 11 0 Q13415 Q13415 ORC1 Origin recognition complex subunit 1 1 AQNEATS(0.028)T(0.972)PHR;AQNEAT(0.002)S(0.238)T(0.76)PHR;AQNEAT(0.005)S(0.186)T(0.808)PHR 145.52 0.00043134 26882450.0 30212.3 26258.0 30566.7 30462.1 29300.800000000003 26118.800000000003 20097.899999999998 22713.4 31173.800000000003 21092.8 True False 29781.46706174275 26197.20121428671 28053.623916874134 32702.384452586663 27577.384551589228 25001.759809896565 21138.470922220054 23768.747483343348 27662.678369332938 24738.662375610686 1.2038430619071652 1.0589578699337425 1.13399922319695 1.3219140128136935 1.1147484101152203 1.010635071140518 0.8544710543064777 0.9607935595893998 1.1181962043592533 1.0 14.594479875165106 -6.72120333369866 3.628130147883939 0.9754164293159167 1.1721862064425048 0.5213977232939839 0.08644015388804126 0.1921007341387405 5.252685835713409 0.031928234399641264 0.03056808045509003 1.9001884164377483e-07 6.72120333369866 0.19676977712658816 AQNTWGCGNSLR ddPTM_PC-9_AZD4547_30min_R2 1 AQNTWGCGNSLR 12 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 116.74 0.0030548000000000003 6780000.0 23835.0 23862.0 39836.0 47650.0 33001.0 27057.0 26095.0 39454.0 26720.0 30124.0 False True 31414.03420120169 31574.92485315725 39307.74861162001 36665.02868516131 28419.38078872473 25365.12151274887 28417.404447286608 33357.29086272627 28132.364650038875 29069.367929031978 1.080657628259886 1.0861923427520739 1.3522051359211984 1.2612943210417535 0.9776401350764117 0.8725721720084726 0.9775721479965773 1.147506576137553 0.9677666442118508 1.0 14.827212082067122 -6.269918021614322 24.727316077003792 0.9913411858588618 1.1985318412047568 0.5175868913062898 0.09673203144736094 485.2457660544725 1415179.8687413235 0.032798574514264746 0.03779161894293973 5.371331772464742e-07 6.269918021614322 0.20719065534589498 AQNTWGCGNSLR ddPTM_PC-9_Lapatinib_30min_R1 1 AQNTWGCGNSLR 12 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 151.13 0.00084593 5799800.0 34385.0 31536.0 30092.0 30471.0 37188.0 29293.0 28112.0 27864.0 28591.0 27238.0 False True 33894.66359456328 31462.980329566064 27617.95191847915 32711.93898827619 35000.674954421054 28040.20667531819 29567.50180692758 29158.663162533063 25370.78050342269 31946.052007646365 1.060996945301739 0.9848785171336766 0.8645184673169857 1.0239743859568784 1.0956181673417285 0.8777362119302472 0.925544784058153 0.9127470009613039 0.7941757716211735 1.0 14.963350029002635 -6.797236781905917 24.999935159648302 0.8980563832794072 0.9979629633985012 0.3271761684754535 0.07398182729181225 231.1539165882566 161430.07198415673 0.026702709269230452 0.023550351560927024 1.595009294337915e-07 6.797236781905917 0.09990658011909404 AQPAQPADEPAEK ddPTM_PC-9_Lapatinib_30min_R1 1 AQPAQPADEPAEK 13 0 P25786;P25786-2;F5GX11 P25786 PSMA1 Proteasome subunit alpha type-1 0 166.04 4.6917e-18 0.0 9552.1 8240.9 10751.0 7704.8 8896.8 9157.8 12552.0 10975.0 10643.0 10941.0 False True 9415.885302359402 8221.818702369384 9867.094280060128 8271.436694459338 8373.507715781789 8766.142241874464 13201.881142592316 11484.938566207313 9444.273264241456 12832.137272033893 0.7337737356410765 0.6407209125083048 0.7689361538832878 0.6445876099288577 0.6525419373459203 0.6831396871804997 1.0288138961359332 0.8950136927881345 0.7359859908001545 1.0 13.647473859795262 -7.239753423487003 24.489694301247408 0.9062045289038068 0.6853584606784433 0.6493606562087756 0.08185116387287639 393.9862626274708 444924.53987075045 0.031041187839754243 0.024020570244590055 5.757667438398714e-08 7.239753423487003 -0.22084606822536346 AQPFAQPPGPWPLS(ph)SPGPR ddPTM_PC-9_AZD4547_30min_R2 1 AQPFAQPPGPWPLSSPGPR 19 0 Q9BUT9 Q9BUT9 FAM195A Protein FAM195A 1 AQPFAQPPGPWPLS(0.5)S(0.5)PGPR 142.4 9.7214e-10 0.0 7926.7 8601.8 10285.0 16432.0 11307.0 9374.2 9108.8 13183.0 8089.6 8577.2 True False 10447.225714397551 11382.163632632974 10148.614179900376 12643.856271869268 9737.218223026897 8788.029792098556 9919.465553916234 11145.87026520303 8517.199740754279 8276.914838696492 1.262212541508142 1.375169837367267 1.2261349038476579 1.5276049733840822 1.1764308818912996 1.06175186810096 1.1984496333755228 1.3466213537794913 1.0290307326752233 1.0 13.014877398239427 -6.4904761910861 24.36941127719584 1.1494896778982526 1.34241926605261 0.43279269611373483 0.11880022605446133 501.4996657728698 377169.5228259989 0.035943671943460064 0.04071772691673541 3.2323904048078955e-07 6.4904761910861 0.19292958815435735 AQPFAQPPGPWPLS(ph)SPGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AQPFAQPPGPWPLSSPGPR 19 0 Q9BUT9 Q9BUT9 FAM195A Protein FAM195A 1 AQPFAQPPGPWPLS(0.5)S(0.5)PGPR;AQPFAQPPGPWPLS(0.5)S(0.5)PGPR 189.45 2.6701e-47 2923100.0 20989.9 22296.5 21491.8 24724.1 29162.0 21405.7 24071.0 27539.1 25507.2 18031.6 True False 24543.075500577917 24509.949167564955 22004.246020105384 23338.88883361371 23447.915441168592 20283.14740941878 21790.820621051556 26816.227805088387 25880.19454511855 21300.586341932925 1.1522253475371116 1.150670163445876 1.033034756268057 1.0956923184629959 1.1008107976355739 0.9522342288526027 1.0230150603015815 1.258943175301105 1.2149991615099383 1.0 14.378605523660472 -10.677441908212083 4.738151607823462 0.9999896707389972 1.1046845743595894 0.12246261256169799 0.08687945915945161 1.0352771287025421e-05 1.8472033550717175e-06 0.09186625126351929 0.02227864071485892 2.1016388681616035e-11 10.677441908212083 0.1046949036205922 AQPFAQPPGPWPLSS(ph)PGPR ddPTM_PC-9_Lapatinib_30min_R1 2 AQPFAQPPGPWPLSSPGPR 19 0 Q9BUT9 Q9BUT9 FAM195A Protein FAM195A 1 AQPFAQPPGPWPLS(0.215)S(0.785)PGPR;AQPFAQPPGPWPLS(0.23)S(0.77)PGPR 180.32 6.2198e-37 0.0 18153.4 17916.2 16914.9 14542.4 15806.5 14014.099999999999 12609.6 11558.2 13406.400000000001 12234.6 True False 17894.529187074168 17874.716139668053 15524.222215402215 15611.896608024277 14876.792746774674 13414.74961146269 13262.46338875334 12095.236167283581 11896.4300563494 14349.334308420228 1.2470633691051165 1.2456826048842644 1.0818775200109847 1.0879875172232327 1.0367583908087592 0.9348691251545292 0.924256352503467 0.8429127029388439 0.8290579758371469 1.0 13.808696188769739 -5.901757890883067 0.6422968958393773 0.8759974462271422 1.2983447243197688 0.8546680936450904 0.05333903815192467 0.38728502020750416 0.28849745228008383 0.03218797556656115 0.10045080241256599 1.2538399668901851e-06 5.901757890883067 0.4223472780926266 AQPGS(ph)PESSGQPK ddPTM_PC-9_AZD4547_30min_R2 4 AQPGSPESSGQPK 13 0 Q05GC8;Q96PN7-2;Q96PN7-3;Q96PN7-4;Q96PN7-5;Q96PN7 Q05GC8;Q96PN7 BCAR2;TRERF1 Transcriptional-regulating factor 1 1 AQPGS(0.893)PES(0.104)S(0.004)GQPK;AQPGS(0.945)PES(0.042)S(0.013)GQPK;AQPGS(0.776)PES(0.182)S(0.043)GQPK;AQPGS(0.958)PES(0.016)S(0.025)GQPK 169.98 0.00018536 93308900.0 76517.7 65184.6 90049.0 104619.0 97444.0 92117.0 75280.1 92287.0 76631.0 87209.0 True False 100848.73693296775 86254.24719567168 88854.89142302852 80500.7058974374 83915.58260587523 86356.90942787018 81979.8830631224 78026.16469428767 80681.55821471279 84155.83945435389 1.1983569718613298 1.0249347847389243 1.0558375033644978 0.9565670833941471 0.9971450959311151 1.0261546909612869 0.9741437266226578 0.927162811281908 0.9587161002472615 1.0 16.360775761140886 -1.5228787560311998 0.7715445149916238 0.9754390214106654 44.976349467587696 0.7916139185458807 0.03289454690396936 191.01597675011894 0.7522310123863917 0.012412909799772765 14646.26021622302 0.029999999257356753 1.5228787560311998 44.00091044617703 AQPGS(ph)PESSGQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AQPGSPESSGQPK 13 0 Q05GC8;Q96PN7-2;Q96PN7-3;Q96PN7-4;Q96PN7-5;Q96PN7 Q05GC8;Q96PN7 BCAR2;TRERF1 Transcriptional-regulating factor 1 1 AQPGS(0.521)PES(0.372)S(0.108)GQPK;AQPGS(0.989)PES(0.01)S(0.001)GQPK;AQPGS(0.99)PES(0.009)S(0.001)GQPK;AQPGS(0.987)PES(0.01)S(0.003)GQPK 184.51 5.1333000000000005e-05 81095300.0 76694.3 76475.9 82692.8 94966.4 99867.0 88137.2 91292.0 91996.0 71796.3 69425.0 True False 89677.13020852771 84067.92194038452 84664.50996619028 89645.74049322309 80298.77825125794 83515.13007532684 82644.16086315662 89581.20247781902 72846.18506224509 82011.20293200223 1.093474147463506 1.0250785128720472 1.0323529827551485 1.0930913983489654 0.9791196248863206 1.0183380695509558 1.0077179447261515 1.0923044568934477 0.8882467572466153 1.0 16.323533378432366 -5.723601526802249 0.29076231148110543 0.9811165732291118 1.1032656651336146 0.226916833347363 0.05249249658533576 8.142679393416314 0.8760491223020773 0.06585991483280175 0.34188667416032936 1.8897244109197902e-06 5.723601526802249 0.12214909190450274 AQPGS(ph)PESSGQPK ddPTM_PC-9_Lapatinib_30min_R1 2 AQPGSPESSGQPK 13 0 Q05GC8;Q96PN7-2;Q96PN7-3;Q96PN7-4;Q96PN7-5;Q96PN7 Q05GC8;Q96PN7 BCAR2;TRERF1 Transcriptional-regulating factor 1 1 AQPGS(0.776)PES(0.174)S(0.05)GQPK;AQPGS(0.919)PES(0.068)S(0.012)GQPK 143.93 8.8804e-05 47265300.0 53877.0 50010.0 48977.0 43455.0 48752.0 44577.0 42916.0 45863.0 47057.0 36274.0 True False 53108.704100168274 49894.204917605246 44950.300116687264 46650.825661630464 45884.50321011979 42670.545624062346 45137.98049039926 47993.962411113054 41756.945127822066 42543.91256793323 1.2483267498109256 1.1727695434202303 1.0565624410992187 1.0965335072823734 1.0785210019612648 1.0029765258643504 1.0609738918188092 1.1281041050109648 0.9815022316329146 1.0 15.376665096975692 -1.5228788809853402 0.5826836179862075 1.043344672963308 13.141483939400134 0.706309764925896 0.04281137476671108 86.4970891165091 0.7115176465246177 0.019695573936530833 1325.0952820882844 0.02999999062583198 1.5228788809853402 12.098139266436826 AQPGSPES(ph)SGQPK ddPTM_PC-9_Lapatinib_30min_R1 1 AQPGSPESSGQPK 13 0 Q05GC8;Q96PN7-2;Q96PN7-3;Q96PN7-4;Q96PN7-5;Q96PN7 Q05GC8;Q96PN7 BCAR2;TRERF1 Transcriptional-regulating factor 1 1 AQPGS(0.308)PES(0.533)S(0.159)GQPK 141.59 7.7815e-05 43029000.0 29320.0 23432.0 28675.0 27246.0 27671.0 24121.0 25328.0 24414.0 28289.0 21347.0 True False 28901.89142337052 23377.744643657785 26317.452188700976 29249.761729991595 26043.446183279153 23089.401058797328 26639.359909144194 25548.363567688866 25102.794923623653 25036.80050691045 1.154376391479944 0.933735308439481 1.0511507722976445 1.1682707509658958 1.0402066420623857 0.9222185179941176 1.064008154787646 1.020432445457127 1.0026358965753226 1.0 14.611762589274562 -6.526340770093369 24.991255737147984 1.0041528223271463 1.0697476997966813 0.20992623335641003 0.06804005258642663 191.6566096335798 1383488.3374098362 0.02268536138152892 0.022788998993664735 2.976180246812566e-07 6.526340770093369 0.06559487746953496 AQPPSSAAS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 AQPPSSAASR 10 0 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;C9K073;C9J2Z7;C9JIH5;C9JWH9;C9JHW9 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 AQPPS(0.044)S(0.136)AAS(0.82)R 69.21600000000001 0.038961 1803800.0 16163.0 9559.3 11754.0 11274.0 10216.0 12095.0 10113.0 8804.9 10743.0 8595.6 True False 15932.512656068815 9537.166028171643 10787.6314917521 12103.127568961509 9615.114965428776 11577.725044822091 10636.601656710964 9214.007797867762 9533.010211194778 10081.338007082939 1.5803966343430764 0.9460218496266098 1.0700594984686491 1.2005477408314356 0.9537538527796009 1.1484313924092042 1.0550783684901655 0.9139667563367274 0.945609620915109 1.0 13.299399507284036 -4.755901864464619 24.990493799164486 1.0325701389394286 1.5803975065786293 0.7755798378358764 0.08941184145663832 85.33206318456084 385058.28041007183 0.02300003949011529 0.19563144911863845 1.7542768629677693e-05 4.755901864464619 0.5478273676392007 AQPQDLIQWGAEYVLLS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 AQPQDLIQWGAEYVLLSR 18 0 D6RAA3 D6RAA3 ROPN1B 1 AQPQDLIQWGAEY(0.458)VLLS(0.542)R 55.011 0.023159 9485300.0 6931.6 4382.6 10379.0 18244.0 16047.0 10680.0 10594.0 11151.0 8993.0 12737.0 True False 9135.704613763364 5799.1897435859155 10241.367678481876 14038.127666990207 13819.151041382573 10012.177911673802 11536.845476702603 9427.869174488282 9468.351620426625 12291.081506841068 0.7432791499005633 0.47182094922714135 0.8332356817243181 1.1421393356782115 1.1243234400236464 0.8145888468887903 0.9386355033347825 0.7670496017165652 0.7703432456417 1.0 13.585324245293274 -5.4625358978133045 6.428048481006739 0.9341573427082603 0.6141972515039453 0.4708495605780517 0.13783037364028913 0.20901588760110734 17.625911617018744 0.03900214092639155 0.08117557513539238 3.447181117651836e-06 5.4625358978133045 -0.319960091204315 AQPQDSATFAHT(ph)PPPAQATPAPGFK ddPTM_PC-9_AZD4547_30min_R2 1 AQPQDSATFAHTPPPAQATPAPGFK 25 0 A0A0A0MQV9;Q9UPS6-2;Q9UPS6 A0A0A0MQV9 SETD1B Histone-lysine N-methyltransferase;Histone-lysine N-methyltransferase SETD1B 1 AQPQDS(0.002)AT(0.006)FAHT(0.992)PPPAQAT(0.001)PAPGFK 79.589 0.00018999 6203500.0 17776.0 13962.0 17944.0 32462.0 25623.0 25174.0 17619.0 25123.0 19911.0 20240.0 True False 23428.39823623081 18474.943458208945 17706.05083559867 24978.387432900457 22065.688735174524 23599.865800419113 19187.056867474337 21240.817619107616 20963.454810887855 19531.40376057653 1.1995245463882238 0.9459096583472401 0.9065426659878758 1.2788833685020877 1.1297543692027585 1.2083036165610705 0.9823695778693979 1.0875213005417195 1.0733204365577589 1.0 14.253508021843437 -5.736204280342183 24.999985304645882 1.1120171050555585 1.0101841467289498 0.12609145475113226 0.10936475777143304 447.99111936105504 443813.7625034766 0.029840592982325425 0.05166053593740251 1.8356746886714188e-06 5.736204280342183 -0.10183295832660866 AQPQDSATFAHT(ph)PPPAQATPAPGFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQPQDSATFAHTPPPAQATPAPGFK 25 0 A0A0A0MQV9;Q9UPS6-2;Q9UPS6 A0A0A0MQV9 SETD1B Histone-lysine N-methyltransferase;Histone-lysine N-methyltransferase SETD1B 1 AQPQDS(0.008)AT(0.017)FAHT(0.975)PPPAQATPAPGFK 83.31700000000001 4.752e-05 3867200.0 14137.0 14408.0 11410.0 13173.0 16317.0 12784.0 13799.0 14216.0 12516.0 11595.0 True False 16530.114881522535 15838.331020845242 11682.057672665971 12434.959517442227 13119.800982564575 12113.584535054204 12491.858823891416 13842.845063097064 12699.022822054309 13697.081714030504 1.2068348007729293 1.1563288700118775 0.8528866160373083 0.9078546640124493 0.9578537426060183 0.8843916381579109 0.9120087829435575 1.0106419273907994 0.927133464425941 1.0 13.741580926372164 -5.175968090137833 5.6137250336795415 0.9299773024072125 1.1909489068202008 0.8213303428891405 0.04673988550873724 0.08453525676837846 4.2760044534802555 0.0120618802215328 0.03330093365868964 6.6685576475626655e-06 5.175968090137833 0.2609716044129883 AQPQDSATFAHT(ph)PPPAQATPAPGFK ddPTM_PC-9_Lapatinib_30min_R1 1 AQPQDSATFAHTPPPAQATPAPGFK 25 0 A0A0A0MQV9;Q9UPS6-2;Q9UPS6 A0A0A0MQV9 SETD1B Histone-lysine N-methyltransferase;Histone-lysine N-methyltransferase SETD1B 1 AQPQDSAT(0.001)FAHT(0.999)PPPAQATPAPGFK 88.633 1.5602e-05 6344400.0 20502.0 14490.0 17092.0 14575.0 17536.0 19030.0 12657.0 17738.0 17099.0 12602.0 True False 20209.63772039368 14456.449295262944 15686.76173702798 15646.894120774685 16504.5669571025 18216.131261096667 13312.317528823365 18562.172235752638 15173.130559547557 14780.238908890504 1.367341749004972 0.9780930730806526 1.061333435387989 1.0586360759948796 1.1166644232776772 1.2324652783615988 0.9006835147174674 1.2558776857515648 1.0265822259761122 1.0 13.851381969052856 -6.697873697063766 0.012757360679125184 7.719532173907262e-06 2.2027970235842345 0.09218772812804976 0.13021506004806588 5346.838483930353 25.559561624129138 2124.746947218801 2285.7081975061406 2.0050550592265802e-07 6.697873697063766 2.2027893040520605 AQPS(ph)SSEDELDNVFFK ddPTM_PC-9_AZD4547_30min_R2 1 AQPSSSEDELDNVFFK 16 0 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 AQPS(0.766)S(0.117)S(0.117)EDELDNVFFK 104.26 0.0066118999999999995 0.0 3475.3 3314.0 4707.2 5879.8 4889.2 6120.9 5053.6 5604.2 6815.4 4637.6 True False 4580.373109269407 4385.185691197854 4644.779452370157 4524.302952004437 4210.418973735129 5738.159155389906 5503.360609879576 4738.199661704532 7175.648130085131 4475.239035575582 1.0234923928885293 0.9798774224880825 1.0378841030494295 1.0109634180518237 0.9408254934015176 1.282201712528612 1.2297355663308747 1.0587590124323112 1.6034111414033632 1.0 12.127749027648916 -6.76372036359279 24.99900395823353 1.2381760777931183 1.0004362898245844 0.3770470919625242 0.1517713371778163 63.5417011397441 696393.5073597336 0.04924521866210998 0.04551955155176108 1.7229776201388412e-07 6.76372036359279 -0.2377397879685339 AQPSAS(ph)LGVGYR ddPTM_PC-9_AZD4547_30min_R2 2 AQPSASLGVGYR 12 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 AQPS(0.109)AS(0.891)LGVGYR;AQPS(0.02)AS(0.98)LGVGYR 126.56 0.00025989 28094000.0 16736.7 29434.0 40215.0 52586.0 33299.0 34677.0 42430.0 48353.0 49168.0 39479.0 True False 22058.622455013738 38947.964886758484 39681.72282398581 40463.110145601124 28676.00863257918 32508.641708156596 46206.187802198554 40881.15489140269 51766.92010153855 38096.85222647237 0.5790143060608524 1.0223407607333683 1.041601090507214 1.062111638648311 0.7527133334300274 0.8533156890470679 1.2128610397394262 1.0730848482803415 1.3588240780052492 1.0 15.21738417871514 -7.261654847651186 24.99995455083758 1.1672829041883144 0.9005480536560448 0.40717083282212674 0.1624575058898337 21.39180540107361 2481762.731645469 0.06532905217985703 0.04721353267321909 5.4745087260941936e-08 7.261654847651186 -0.26673485053226953 AQPSAS(ph)LGVGYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AQPSASLGVGYR 12 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 AQPS(0.233)AS(0.767)LGVGYR;AQPS(0.139)AS(0.861)LGVGYR 116.9 0.00065542 15673200.0 36199.0 25280.9 15778.2 26243.6 32309.0 24356.9 30522.0 52453.0 24237.0 8903.1 True False 42326.77573716026 27790.62067635247 16154.412127156724 24773.256174899183 25978.283382097117 23079.581286128123 27630.73519985608 51076.164328547435 24591.420273100863 10517.161553099173 4.024543649297419 2.6424069399374392 1.5360049425499582 2.35550780976632 2.470085036816982 2.1944686472299253 2.6272045989170834 4.856459042743945 2.3382183632858924 1.0 13.36045777183996 -7.543273330320861 24.995692728469514 3.1067689624158352 2.478946419952202 0.0 1.0719856737072793 732.3268172272667 897532.2624241569 0.48788907210574795 0.2817202929761134 2.8623759198855944e-08 7.543273330320861 -0.6278225424636332 AQPSAS(ph)LGVGYR ddPTM_PC-9_Lapatinib_30min_R1 2 AQPSASLGVGYR 12 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 AQPS(0.075)AS(0.925)LGVGYR;AQPS(0.124)AS(0.876)LGVGYR 109.95 0.0012506 24644000.0 35006.0 40575.0 22182.3 24444.0 40499.0 40601.0 46133.0 35626.0 45701.0 47291.0 True False 34506.80802068581 40481.05108042055 20358.55692015419 26241.6933027936 38116.92844409748 38864.589875553655 48521.5410094974 37281.31401910723 40553.672127135134 55465.18633870343 0.6221345369682291 0.7298461206497922 0.36705108670928693 0.4731200782874181 0.6872225797878481 0.7007024124686672 0.8748107454862948 0.6721570137968228 0.7311554292721615 1.0 15.759294903162614 -6.640107840257197 2.29761533618175 0.7871088332059432 0.5508776462901122 0.46803550233277214 0.12414988372345452 0.30419930140322526 3.2761102653334757 0.04748265013332276 0.04733055347901708 2.2902988749054552e-07 6.640107840257197 -0.236231186915831 AQPSMS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 AQPSMSPK 8 0 Q969S3 Q969S3 ZNF622 Zinc finger protein 622 1 AQPS(0.039)MS(0.961)PK;AQPS(0.094)MS(0.906)PK 90.82700000000001 0.0091832 35925000.0 167175.0 143987.0 135123.0 160808.0 168940.0 153707.0 163997.0 155564.0 136131.0 157832.0 True False 220333.17254398594 190527.98193075013 133331.1807322004 123736.20005883346 145485.5971166681 144095.67699153954 178592.4152957143 131525.15830509295 143326.6067430554 152306.34972032218 1.4466446930714338 1.250952322609095 0.8754144589311896 0.812416555751276 0.9552168861234025 0.9460910674843185 1.1725868003774027 0.8635566313985634 0.9410415718467671 1.0 17.2166165641219 -5.069415533917517 3.389694586043166 0.9453258031408839 1.4243655467956247 0.7603394966522048 0.09327244309062234 0.11654121358464871 2.523553471894577 0.02581896209124515 0.09715225163303848 8.522842563176371e-06 5.069415533917517 0.4790397436547408 AQPSMS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 AQPSMSPK 8 0 Q969S3 Q969S3 ZNF622 Zinc finger protein 622 1 AQPS(0.004)MS(0.996)PK;AQPS(0.022)MS(0.978)PK;AQPS(0.008)MS(0.992)PK 101.39 0.0045996000000000006 88778200.0 274113.0 239516.0 212177.0 234531.0 215471.0 200962.0 175043.0 181149.0 186831.0 178457.0 True False 270204.09835383174 238961.4154178186 194732.62608690554 251779.19211248128 202797.41941228497 192367.32372530282 184105.87004802332 189565.84385693714 165788.12536235037 209303.05467099458 1.2909706395760352 1.1417005632977708 0.9303859725936995 1.2029408386239528 0.9689176287038148 0.9190851228984059 0.8796138706022282 0.9057003212634305 0.7920960619660056 1.0 17.67523384158006 -2.717900755310578 0.3553450895505447 0.8769018853784335 2.9639585466345446 0.6259885207421411 0.09169353349826942 17.661075941636895 0.5441256532343645 0.07871119648414356 21.323534391318155 0.0019146934195123724 2.717900755310578 2.0870566612561112 AQPSS(ph)SEDELDNVFFK ddPTM_PC-9_AZD4547_30min_R2 1 AQPSSSEDELDNVFFK 16 0 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 AQPS(0.195)S(0.682)S(0.123)EDELDNVFFK 81.594 0.042384 0.0 3356.4 4142.0 4811.2 4558.6 3680.2 3872.5 4049.5 5865.5 4588.0 6364.0 True False 4423.665382543043 5480.820498775351 4747.400344417763 3507.6851996679184 3169.2677548760576 3630.351962823669 4409.897655079027 4959.121750781182 4830.512313412358 6141.198297050841 0.7203260941219566 0.8924675989386924 0.7730413699061933 0.5711727630342759 0.5160666699849149 0.5911471649705655 0.7180842307594548 0.8075169553086533 0.7865748799761265 1.0 12.584304472592812 -8.542712837181805 1.0997573647437386 0.9932939066598216 0.6826613251074404 0.448984677676882 0.1050520121194795 0.5980856538088373 1.5829626087551936 0.11645984499538964 0.03739766154465974 2.866072438826809e-09 8.542712837181805 -0.31063258155238127 AQPSSS(ph)EDELDNVFFK ddPTM_PC-9_AZD4547_30min_R2 1 AQPSSSEDELDNVFFK 16 0 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 AQPS(0.029)S(0.289)S(0.682)EDELDNVFFK 107.98 0.0044231999999999995 0.0 3860.5 4242.4 5811.6 7271.6 4451.8 5345.5 5716.2 7151.2 6124.6 3747.7 True False 5088.058696611668 5613.672835346341 5734.53438676802 5595.244965100088 3833.7444136615495 5011.245039967444 6224.930726253292 6046.146358228012 6448.333852381286 3616.4941637111 1.4069036105924495 1.5522416410001385 1.5856611754858947 1.5471461342988797 1.0600720587718344 1.385663798452009 1.7212611010729573 1.6718252773353577 1.783034497078869 1.0 11.820376108108047 -7.243390372471565 24.352977231528662 1.6000156704360586 1.425372094784868 0.03601058171267202 0.24603884462526626 1418.2623665873427 1913620.297334746 0.0933737424991234 0.0721697303050074 5.709651848473713e-08 7.243390372471565 -0.1746435756511906 AQPSSS(ph)EDELDNVFFK ddPTM_PC-9_Lapatinib_30min_R1 1 AQPSSSEDELDNVFFK 16 0 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 AQPS(0.412)S(0.056)S(0.532)EDELDNVFFK 110.22 0.003662 0.0 3355.5 7601.8 5398.4 4898.9 5296.2 4619.5 4889.3 4364.7 5997.3 4110.4 True False 3307.6499546766613 7584.198499153203 4954.564390426621 5259.181448251327 4984.687928729825 4421.934753580455 5142.444030471368 4567.499896120734 5321.820919631243 4820.877163236278 0.6861095694162471 1.5731988686602199 1.027730892670287 1.0909179533462359 1.0339794522753574 0.9172469249583596 1.0667029788038036 0.9474416670377367 1.1039113297088614 1.0 12.235079954751448 -5.926418831704283 2.114203819801988 1.0084978116069994 1.1457867125042618 0.02490121247353705 0.20763411436353632 0.8861763249822792 8.032122319612759 0.06140349471283797 0.10239249017220915 1.1846257491980532e-06 5.926418831704283 0.13728890089726242 AQPSVS(ph)LGAPYR ddPTM_PC-9_AZD4547_30min_R2 2 AQPSVSLGAPYR 12 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 AQPS(0.013)VS(0.987)LGAPYR;AQPS(0.003)VS(0.997)LGAPYR 140.31 5.6200000000000004e-05 21345000.0 33089.0 27672.1 43818.0 65827.0 38334.0 31743.0 48790.0 63302.0 59265.0 41294.0 True False 43610.613706044176 36616.565167590874 43236.94468982741 50651.60216701183 33011.98579300551 29758.105191972052 53132.21548124599 53520.13043524858 62397.626908104554 39848.309628915405 1.0944156505549412 0.9188988318094312 1.085038364047771 1.2711104345128144 0.8284413090649846 0.7467846307432442 1.3333618408418333 1.3430966315422423 1.5658788914555746 1.0 15.282230905729937 -7.325621253759127 13.186720395845878 1.3393231904537033 0.9971787091352416 0.40457318448879953 0.18868675427134396 1.865389760443444 381.82278102102754 0.08009139755034501 0.053990035962079866 4.724749048592486e-08 7.325621253759127 -0.34214448131846165 AQPSVS(ph)LGAPYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AQPSVSLGAPYR 12 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 AQPS(0.361)VS(0.639)LGAPYR;AQPS(0.079)VS(0.921)LGAPYR 96.135 0.0043783 6155100.0 20325.2 17287.9 17770.6 19921.2 22670.0 24290.0 19778.7 36956.0 19094.0 12757.8 True False 23765.85491900133 19004.128460249187 18194.318499375786 18805.07974940182 18227.97623795666 23016.189639898836 17905.118350612465 35985.94415811866 19373.21362770094 15070.688149310758 1.576958841132164 1.2609993831713864 1.2072652767490173 1.2477917108424708 1.2094986013488904 1.5272155731622286 1.1880756985493948 2.387810284546591 1.2854896495610226 1.0 13.879457673521124 -6.823884360724458 6.7162958797280226 1.5485804262853247 1.2904900138582902 0.03903678605754346 0.3609843440037556 0.5125372596840858 43.33449164881912 0.12456755701921579 0.1104039539825473 1.5000842086598342e-07 6.823884360724458 -0.25809041242703445 AQPSVS(ph)LGAPYR ddPTM_PC-9_Lapatinib_30min_R1 4 AQPSVSLGAPYR 12 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 AQPS(0.06)VS(0.94)LGAPYR;AQPS(0.099)VS(0.901)LGAPYR;AQPS(0.086)VS(0.914)LGAPYR;AQPS(0.014)VS(0.986)LGAPYR 113.69 0.00080322 22461800.0 50805.0 57938.0 55917.0 40247.5 67656.0 48588.0 67418.0 50739.6 60319.0 60280.0 True False 50080.51138350404 57803.84812070013 51319.720105862 43207.43541172417 63676.60709681374 46510.00450416 70908.57416119259 53097.14705001659 53525.23903277087 70699.31768194883 0.7083591896713701 0.817601216191918 0.7258870635319457 0.6111435983880227 0.9006679156830372 0.6578564833311692 1.0029598090350056 0.7510277155556413 0.757082823253853 1.0 16.10940867122318 -7.240545025302099 24.998939296703654 0.8570199322412293 0.7418111971982256 0.2769408931950481 0.10928776649400382 1296.3589580984585 1551023.6080112627 0.040673422109120526 0.0314713444913118 5.747182320800142e-08 7.240545025302099 -0.11520873504300366 AQQCVS(ph)PSSSLCR ddPTM_PC-9_AZD4547_30min_R2 3 AQQCVSPSSSLCR 13 0 B9EGE7;Q8TCN5-2;Q8TCN5 B9EGE7 ZNF507 Zinc finger protein 507 1 AQQCVS(0.333)PS(0.333)S(0.333)S(0.002)LCR;AQQCVS(0.497)PS(0.497)S(0.006)S(0.001)LCR;AQQCVS(0.919)PS(0.076)S(0.002)S(0.002)LCR 169.17 5.4851999999999996e-05 20511300.0 27125.3 26421.1 35202.8 48551.0 46826.0 37328.0 26870.5 41434.0 38512.0 34868.8 True False 35750.581158710134 34961.20388222921 34735.9878708991 37358.317055472566 40325.018175595425 34993.8742590786 29261.92244494403 35031.32735859987 40547.66569619372 33648.0539252367 1.062485849498015 1.039026029853323 1.0323327449510067 1.1102667969588902 1.1984353765360223 1.0399969738764745 0.8696468006726835 1.041110057551521 1.2050523274328853 1.0 15.038235446833813 -6.983838683728826 24.98867107749305 1.0212986417962027 1.087384912617403 0.09557082887332102 0.08743848949794042 588.2652495350338 909574.7532932776 0.032792502928324946 0.028912953575724692 1.0379138715639855e-07 6.983838683728826 0.06608627082120044 AQQCVS(ph)PSSSLCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AQQCVSPSSSLCR 13 0 B9EGE7;Q8TCN5-2;Q8TCN5 B9EGE7 ZNF507 Zinc finger protein 507 1 AQQCVS(0.493)PS(0.493)S(0.009)S(0.005)LCR;AQQCVS(0.727)PS(0.264)S(0.009)S(0.001)LCR;AQQCVS(0.966)PS(0.03)S(0.003)SLCR 178.67 0.00012108 17918400.0 26421.1 30596.9 35511.2 35530.8 39824.0 37050.5 32975.6 34862.6 33220.7 24950.2 True False 30893.670389488227 33634.35802413238 36357.92168497596 33540.124468407805 32020.773078976003 35107.50655632242 29851.912445330403 33947.49368997804 33706.48989011022 29473.47375432547 1.0481855870468724 1.1411738672030902 1.2335811512424844 1.1379766344469497 1.086426844215358 1.191156049299079 1.012839975842664 1.1517981888713056 1.1436212158454353 1.0 14.847129486594138 -7.241094010000642 24.974074899274058 1.08971467280003 1.1415753984591177 0.16805479826342706 0.06589245575382294 1775.2967623643215 2179189.3532187575 0.02536454864117368 0.019624956169910245 5.739921989481246e-08 7.241094010000642 0.051860725659087725 AQQCVS(ph)PSSSLCR ddPTM_PC-9_Lapatinib_30min_R1 2 AQQCVSPSSSLCR 13 0 B9EGE7;Q8TCN5-2;Q8TCN5 B9EGE7 ZNF507 Zinc finger protein 507 1 AQQCVS(0.446)PS(0.276)S(0.276)S(0.002)LCR;AQQCVS(0.774)PS(0.225)S(0.001)SLCR 191.01 1.3482e-05 13744800.0 17847.9 23167.6 31353.0 18878.9 25016.0 26574.0 20903.0 21056.0 26392.0 18905.0 True False 17593.38567309599 23113.95684561311 28775.277366079918 20267.31728416421 23544.608063348325 25437.491967019603 21985.255060835487 22034.33862870716 23419.45503991926 22172.704060670927 0.7934704592166747 1.0424509695509687 1.2977793456018012 0.9140661070795413 1.0618735540294713 1.1472435611558822 0.9915459567167574 0.9937596500821388 1.0562290903191989 1.0 14.43649710361259 -4.7669529714947885 5.979497673214818 1.060754601363223 0.7843696936084925 0.38754790160532493 0.09911148438330213 0.1322554442039466 18.057936806206143 0.024548538165680204 0.14928844722496967 1.7102004977759134e-05 4.7669529714947885 -0.27638490775473046 AQQCVSPS(ph)SSLCR ddPTM_PC-9_AZD4547_30min_R2 1 AQQCVSPSSSLCR 13 0 B9EGE7;Q8TCN5-2;Q8TCN5 B9EGE7 ZNF507 Zinc finger protein 507 1 AQQCVS(0.221)PS(0.759)S(0.02)SLCR 198.48 6.8071e-07 6541400.0 16071.0 14582.0 25326.0 36393.0 32393.0 25450.0 19086.0 32977.0 20543.0 26250.0 True False 21181.243702433923 19295.346333448124 24990.16069228558 28003.15611624503 27895.79109388082 23858.607476788235 20784.61702551877 27881.162386073003 21628.861040634285 25330.995489878173 0.8361788904386952 0.761728702733306 0.9865447531373654 1.1054897596675428 1.1012512755382036 0.9418740564823724 0.8205211292948966 1.1006737732519765 0.8538496266077188 1.0 14.628616154589976 -5.26987151936677 23.53631687757986 0.9928722716628162 0.7989537922362673 0.3884668948015648 0.09515522151828451 251.66661005154066 702472.2091528187 0.02559885011174227 0.05486339991398897 5.3719069406587786e-06 5.26987151936677 -0.19391847942654894 AQQCVSPS(ph)SSLCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQQCVSPSSSLCR 13 0 B9EGE7;Q8TCN5-2;Q8TCN5 B9EGE7 ZNF507 Zinc finger protein 507 1 AQQCVS(0.212)PS(0.781)S(0.007)SLCR 136.14 5.4000000000000005e-05 5408200.0 4537.9 6669.1 6523.5 6492.5 8884.0 6740.6 6958.3 6926.9 5787.9 5499.6 True False 5306.076842389552 7331.164173453561 6679.044980511522 6128.746273969001 7143.243974327615 6387.111069851873 6299.159450270579 6745.076214657224 5872.53708786898 6496.633945190354 0.8167424680465173 1.1284557873052141 1.0280777764085374 0.9433725719618679 1.0995300080922623 0.9831415966695239 0.9696035675419313 1.0382416912454793 0.9039353513547718 1.0 12.665476703046904 -8.251045281976479 24.90154946864285 0.9519676702618955 1.0057892561134112 0.048455714942042816 0.08453130036342121 1770.7286129653394 4242231.858326108 0.05488734170967798 0.020245856589176835 5.6098948107592315e-09 8.251045281976479 0.05382158585151564 AQQCVSPS(ph)SSLCR ddPTM_PC-9_Lapatinib_30min_R1 2 AQQCVSPSSSLCR 13 0 B9EGE7;Q8TCN5-2;Q8TCN5 B9EGE7 ZNF507 Zinc finger protein 507 1 AQQCVS(0.239)PS(0.759)S(0.001)SLCR;AQQCVS(0.312)PS(0.646)S(0.031)S(0.01)LCR 92.906 0.0043855 12310000.0 16844.0 21344.0 26786.0 24334.0 28755.0 20921.0 22723.0 20500.8 32516.0 23315.0 True False 16603.801471188704 21294.57927937145 24583.75847695012 26123.60353584434 27063.687434505144 20026.257599232984 23899.48575550711 21453.3420098499 28853.70567134036 27344.966684715306 0.6071977217097703 0.7787385344036359 0.8990231643138703 0.9553349922509266 0.989713673691642 0.7323562624937051 0.8739994468110259 0.7845444559214411 1.055174285052919 1.0 14.73898768396525 -4.879894204632945 2.185440757019747 0.9003784333895429 0.5638751852460313 0.5061369225728429 0.0935603345177545 0.4423154089296365 2.921329870414985 0.025055806215634805 0.27245534499476515 1.3185779087526899e-05 4.879894204632945 -0.3365032481435116 AQQEAEAAQR ddPTM_PC-9_Lapatinib_30min_R1 1 AQQEAEAAQR 10 0 K7EK42;A0A494C0X0;Q99426;K7EP07;Q99426-2 K7EK42 TBCB Tubulin-folding cofactor B 0 101.38 0.016697 2292100.0 9314.0 9800.3 7817.0 9062.2 9968.3 7503.4 7990.9 7567.1 11383.0 9207.4 False True 9181.180652021594 9777.608007478642 7174.316434492605 9728.664418612994 9381.984192431844 7182.497073279701 8404.629702226011 7918.695091056703 10100.926671696003 10798.886821910683 0.8501969511703001 0.9054273990204351 0.6643570353877669 0.9008951180851129 0.86879178818654 0.6651145800238026 0.7782866735090898 0.7332880899344051 0.9353673983508619 1.0 13.398594982745562 -8.441450192421668 4.588177655964085 0.9986154174405671 0.7965749655913648 0.4116461583627413 0.0837736499187159 0.19652011714694229 6.955357518382734 0.08157490680957266 0.021295083104219983 3.6186768957836817e-09 8.441450192421668 -0.20204045184920238 AQQELEEQTRR ddPTM_PC-9_AZD4547_30min_R2 1 AQQELEEQTRR 11 1 P26038 P26038 MSN Moesin 0 83.045 0.008396899999999999 7532700.0 35402.0 28180.0 48420.0 63719.0 54687.0 42275.0 30004.0 56623.0 43643.0 36108.0 False True 46659.09959265546 37288.633910065044 47777.91916293403 49029.56899873652 47094.65401633256 39631.537567042105 32674.2978745502 47873.216417097094 45949.87988104964 34843.86991041985 1.3390906266327878 1.0701633890245383 1.3712001360860988 1.4071218014757458 1.351590800258647 1.1374034419520815 0.9377344697518557 1.373935115134295 1.318736408991947 1.0 15.088617244316259 -6.766940113149533 24.846263069921243 1.1634436017456689 1.3036658692458913 0.21118063271082788 0.1483570684474873 244.7276088207138 1105400.9607307378 0.0544775134083074 0.04940303071884529 1.7102511331740466e-07 6.766940113149533 0.14022226750022249 AQQELEEQTRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AQQELEEQTRR 11 1 P26038 P26038 MSN Moesin 0 ; 107.18 0.0014820999999999999 15665700.0 69096.0 62811.0 95507.0 99798.0 115110.0 95658.0 81930.0 80735.0 86163.0 66637.0 False True 80792.58809179318 69046.4609765622 97784.24909231455 94206.64160948145 92555.02182404899 90641.5260837153 74168.9972781667 78615.79179580323 87422.97087061882 78717.76060179835 1.0263578063467855 0.8771395482887352 1.2422132990668515 1.1967647566352293 1.175783217363713 1.1514749071970494 0.9422142691959694 0.9987046277077045 1.1105876259978564 1.0 16.264401558374026 -7.249567315462835 24.644005925586914 1.0127686798815858 1.113686428538483 0.17903189232748085 0.10353413736945474 1213.9313256846262 2519879.413694286 0.04372829480980882 0.03359669338889831 5.629018610793183e-08 7.249567315462835 0.10091774865689729 AQQELEEQTRR ddPTM_PC-9_Lapatinib_30min_R1 2 AQQELEEQTRR 11 1 P26038 P26038 MSN Moesin 0 ; 110.08 0.0012537000000000002 17832000.0 118184.0 92937.0 114845.0 96909.0 100765.0 95627.0 78093.0 80045.0 105318.0 79936.0 False True 116498.67448770891 92721.81008653236 105402.88741452021 104036.01113894723 94838.20081161226 91537.2561274246 82136.2734280164 83764.182918639 93455.97779229365 93752.83109197521 1.2426150029903538 0.9890027747062766 1.1242635148917886 1.109683941564216 1.0115769274057682 0.976367914027289 0.8760937933430244 0.8934576368841922 0.9968336604215148 1.0 16.51657463634595 -6.5354812303032 1.9362491548688077 0.9339032728848147 1.1096386567293144 0.5694204542112287 0.06851599858966112 0.24240818289323385 1.835428170282992 0.024973424475114296 0.02684592440136786 2.914196080176818e-07 6.5354812303032 0.17573538384449972 AQQELVPPQQQAS(ph)PPQLPK ddPTM_PC-9_AZD4547_30min_R2 3 AQQELVPPQQQASPPQLPK 19 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0 O15027 SEC16A Protein transport protein Sec16A 1 AQQELVPPQQQAS(1)PPQLPK;AQQELVPPQQQAS(1)PPQLPK;AQQELVPPQQQAS(1)PPQLPK 73.831 0.0026133000000000003 46139000.0 145486.0 148057.0 199038.0 231215.0 214671.0 208174.0 168525.0 213025.0 185408.0 203653.0 True False 191747.52170321054 195913.529837562 196398.62607088094 177911.95398614003 184867.6371411877 195156.8468712339 183523.39852381605 180106.8810775142 195208.28836206606 196523.1704571485 0.975699309435987 0.9968978689985086 0.9993662610572696 0.9052975970837668 0.9406913022579073 0.9930475191157547 0.9338511998198858 0.9164663925304736 0.9933092770077758 1.0 17.584339893449645 -5.698023412900244 24.999998341933267 0.9513341807702509 0.9912790157478049 0.2095139035516106 0.03156589593800284 90.19187595519993 35554.33749106276 0.00842504524942826 0.014592601940597603 2.004363968799878e-06 5.698023412900244 0.03994483497755397 AQQELVPPQQQAS(ph)PPQLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AQQELVPPQQQASPPQLPK 19 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0 O15027 SEC16A Protein transport protein Sec16A 1 AQQELVPPQQQAS(1)PPQLPK;AQQELVPPQQQAS(1)PPQLPK;AQQELVPPQQQAS(1)PPQLPK;AQQELVPPQQQAS(1)PPQLPK 84.947 0.00075034 51166600.0 236502.0 253343.0 256182.0 275731.0 291068.0 275426.0 288868.0 268381.0 268374.0 214345.0 True False 276537.117472578 278493.21875444136 262290.35045564536 260282.68600196313 234035.31484912065 260982.1757002378 261504.33181678836 261336.28312317433 272298.4620362734 253204.05174591337 1.0921512336227504 1.0998766284905477 1.0358852816417408 1.0279562440144245 0.924295299523768 1.0307187973521437 1.0327809923010403 1.0321173034996356 1.0754111561750244 1.0 17.94994096524954 -5.370209965132868 2.9112588264359958 1.0167006484423426 1.0976754373882975 0.4190963761313795 0.0362897553155939 0.2675919616471859 4.301897193893604 0.010545169085516396 0.026967983913882235 4.263733334102063e-06 5.370209965132868 0.08097478894595489 AQQELVPPQQQAS(ph)PPQLPK ddPTM_PC-9_Lapatinib_30min_R1 2 AQQELVPPQQQASPPQLPK 19 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0 O15027 SEC16A Protein transport protein Sec16A 1 AQQELVPPQQQAS(1)PPQLPK;AQQELVPPQQQAS(1)PPQLPK 100.92 0.00023907 43921000.0 149875.0 127777.0 137761.0 132065.0 146197.0 141302.0 129900.0 124000.0 145196.0 106898.0 True False 147737.75501629128 127481.14020709548 126434.82235283803 141777.50065592496 137597.97989436088 135258.84285105023 136625.58639441835 129761.49268425583 128842.49749833732 125375.17686736841 1.1783652769844524 1.0167972910774428 1.0084517965353748 1.130825927415506 1.097489816823331 1.078832718171457 1.089733947406124 1.0349855204713099 1.0276555592391061 1.0 16.935892210492575 -8.004871256007002 1.9760412725973135 1.00961698771914 1.0823807982780669 0.2873160211207202 0.04705482216807167 0.5006573575948684 3.559997682286136 0.04052438226998004 0.013518882718861584 9.88846188730475e-09 8.004871256007002 0.07276381055892678 AQQEQELAADAFK ddPTM_PC-9_Lapatinib_30min_R1 1 AQQEQELAADAFK 13 0 K7ELL7;P14314-2;P14314 K7ELL7 PRKCSH Glucosidase 2 subunit beta 0 105.95 0.0054008 4205000.0 33737.0 23466.0 13588.0 15029.0 14979.0 16958.0 18394.0 16627.0 13258.0 13316.0 False True 33255.904193391936 23411.665918746752 12470.847091196818 16134.28279527429 14097.964669847075 16232.745871028763 19346.35131746678 17399.551119847747 11764.744427070678 15617.652857545309 2.1293791388969896 1.4990514984737893 0.798509686759481 1.0330798707361064 0.9026942011350937 1.0393844721158778 1.2387489652851411 1.1140951382743507 0.7532978568791029 1.0 13.930890029878256 -4.924637571920586 2.822576352494922 1.0002115407355823 2.1793943757774636 0.86680773302503 0.14043252018185473 0.10981990494587168 1.498197675485892 0.037768889196336496 0.2593296878396505 1.1894944720573682e-05 4.924637571920586 1.1791828350418814 up AQQVSQGLDVLTAK ddPTM_PC-9_Lapatinib_30min_R1 2 AQQVSQGLDVLTAK 14 0 P18206;P18206-2 P18206 VCL Vinculin 0 ; 190.27 3.5172e-08 3050200.0 32442.0 36080.0 32156.0 29824.0 36276.0 30740.0 30519.0 31271.0 33925.0 35204.0 False True 31979.37113086582 35996.4589767486 29512.257805749563 32017.356449947463 34142.31700136007 29425.32185843992 32099.12448938615 32723.964820398058 30104.009253912558 41288.964493618594 0.7745258696378395 0.8718179159545653 0.7147735034699362 0.7754458568438038 0.8269114379615146 0.7126679542420528 0.7774262416861344 0.7925595912064034 0.7291054552497986 1.0 15.333468616454082 -10.566650808872652 6.015410705388305 1.000000395717171 0.7763912940763809 0.6740568124035076 0.04692414135836483 2.4259169478976056e-07 3.8540261621887745e-08 0.04426227530066978 0.010735159649870152 2.712371616844411e-11 10.566650808872652 -0.22360910164079018 AQRPQS(ph)CTSVGR ddPTM_PC-9_AZD4547_30min_R2 1 AQRPQSCTSVGR 12 1 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 AQRPQS(0.791)CT(0.104)S(0.104)VGR 58.824 0.031454 4467700.0 7147.1 7042.8 8577.5 14890.0 11003.0 10938.0 7518.4 11323.0 9058.1 12019.0 True False 9419.729131084903 9319.247370539597 8463.756745561062 11457.340548206757 9475.423375604929 10254.04513088839 8187.5230349292815 9573.29052665508 9536.892673522345 11598.218468298883 0.8121703481298969 0.8035067968422616 0.7297462768695757 0.987853486250739 0.8169723135931491 0.8841051889922157 0.7059293681446018 0.8254104328885952 0.8222722049588299 1.0 13.501615598321504 -11.819503922521426 1.8767092841369166 1.644645557803107 0.8211006343606154 0.3491948953482753 0.07335694223149841 5056489.666292061 665309.5840017552 13792796.078667631 0.020463838306550325 1.515291117619407e-12 11.819503922521426 -0.8235449234424915 AQS(ph)GSDSSPEPK ddPTM_PC-9_AZD4547_30min_R2 1 AQSGSDSSPEPK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AQS(0.649)GS(0.141)DS(0.105)S(0.105)PEPK 142.95 8.298e-05 5657500.0 28640.0 21256.0 28738.0 39133.0 34186.0 30322.0 26215.0 31286.0 31340.0 35439.0 True False 37746.92425099292 28126.586316264806 28356.915342924363 30111.491448823053 29439.863993313655 28425.960546607945 28548.084214815804 26451.46758075869 32996.568418121904 34198.29139679208 1.1037663786481948 0.8224558937731953 0.8291909971146786 0.8804969552264712 0.8608577443747735 0.8312099635853268 0.8347810094832314 0.7734733666618189 0.9648601456509344 1.0 15.061636627030463 -4.756653160162422 24.986399808883856 0.8563121264100221 1.103766757360389 0.537433428695336 0.06547688740662487 102.19337210361576 533435.7244849039 0.01504724632359548 0.11968144589816922 1.751244723786148e-05 4.756653160162422 0.24745463095036702 AQS(ph)GSDSSPEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQSGSDSSPEPK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AQS(0.646)GS(0.118)DS(0.118)S(0.118)PEPK 122.97 0.00037654 4643100.0 18665.0 25533.0 20685.0 24999.0 29339.0 22165.0 24167.0 22431.0 26006.0 19710.0 True False 21824.615849446003 28067.747498281602 21178.208848299346 23598.38707785154 23590.233561773726 21002.628380747537 21877.726806071758 21842.210017609043 26386.288551481637 23283.26697572584 0.9373519563298155 1.2054900855427144 0.9095892286240955 1.0135341875542736 1.0131839997526084 0.902048170587229 0.9396330346974314 0.9381076135226563 1.133272602121982 1.0 14.507005882769645 -4.447533443560937 15.532253678233806 1.0006913791106151 0.00015650822784837659 0.044580478035356474 0.09247524375597242 221218.4117800541 901907.2840309421 0.02275364789623836 7268348.249501848 3.568342696155582e-05 4.447533443560937 -1.0005348708827668 AQS(ph)GSDSSPEPK ddPTM_PC-9_Lapatinib_30min_R1 1 AQSGSDSSPEPK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AQS(0.857)GS(0.057)DS(0.029)S(0.057)PEPK 121.24 0.00045597 5404000.0 27850.0 23926.0 25923.0 26093.0 28485.0 23832.0 21971.0 23985.0 25110.0 21353.0 True False 27452.85389293551 23870.600817009068 23791.71100567379 28011.966263696337 26809.56830366471 22812.760915105406 23108.550875071367 25099.430661547358 22281.847379977746 25043.837598915958 1.096191978745455 0.9531526756922559 0.9500026068969412 1.1185173259911594 1.0705055963477892 0.9109131467971535 0.922724034757023 1.0022198300245249 0.8897137785681151 1.0 14.61216803050652 -6.763385631342445 24.999998029993254 0.943853511575961 1.0325990661637925 0.36503519410730145 0.060842844294801045 64.49397398110304 828430.805162868 0.021706654147388538 0.020109219033517492 1.7243061161635285e-07 6.763385631342445 0.08874555458783151 AQS(ph)LLSTDR ddPTM_PC-9_AZD4547_30min_R2 2 AQSLLSTDR 9 0 O00231-2;O00231;J3QRY4 O00231-2 PSMD11 26S proteasome non-ATPase regulatory subunit 11 1 AQS(0.995)LLS(0.004)TDR;AQS(0.995)LLS(0.005)TDR 107.97 0.0024671 23700000.0 80475.0 89257.0 110641.0 113307.0 123000.0 100807.0 110331.0 178159.0 135759.0 124041.0 True False 106064.3760160147 118107.57973423247 109173.82804845479 87185.82172569935 105923.57313454573 94503.5223541295 120150.24526053197 150628.62023654 142934.94358250833 119698.36234514198 0.8860971356499046 0.9867100720532617 0.9120745339327164 0.7283794031726603 0.8849208214655636 0.7895139123260108 1.0037751804330206 1.2584016797340365 1.1941261415955322 1.0 16.869043888600395 -7.539287112959249 4.821720562274656 1.1671739752936088 0.868272116405093 0.6731299042223338 0.0893070599841452 0.10696925769613419 6.6755401964815 0.04329358411626817 0.0253862528854582 2.888769479611291e-08 7.539287112959249 -0.2989018588885157 AQS(ph)LLSTDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AQSLLSTDR 9 0 O00231-2;O00231;J3QRY4 O00231-2 PSMD11 26S proteasome non-ATPase regulatory subunit 11 1 AQS(1)LLSTDR;AQS(1)LLSTDR;AQS(0.872)LLS(0.127)T(0.001)DR 114.76 0.0020195 24645900.0 101760.0 134140.0 122216.0 103115.0 157310.0 119537.0 117398.0 148192.0 112635.0 84531.0 True False 118985.95814838578 147456.53269962393 125130.09294676097 97337.80085334048 126486.23475928398 113268.26928713807 106277.21155208368 144302.1170224031 114282.07379051503 99855.80115297204 1.1915778229660157 1.4766947037331455 1.2531078966065325 0.9747836352965196 1.2666888983797346 1.1343183668780452 1.0643068337038777 1.4451049949651142 1.144471051966655 1.0 16.607558623458168 -5.523227317975248 24.999956700211765 1.1625896877850939 1.3418275441774359 0.21654184098513174 0.14279680170430992 16.854371420474173 1208794.8235292374 0.037709043572584915 0.06613326814181171 2.997593111162334e-06 5.523227317975248 0.17923785639234202 AQS(ph)LLSTDR ddPTM_PC-9_Lapatinib_30min_R1 1 AQSLLSTDR 9 0 O00231-2;O00231;J3QRY4 O00231-2 PSMD11 26S proteasome non-ATPase regulatory subunit 11 1 AQS(1)LLSTDR 142.19 0.00067509 6909300.0 26604.0 39710.0 31306.0 29651.0 46596.0 32935.0 41519.0 42598.0 41587.0 51417.0 True False 26224.62208142391 39618.05393477512 28732.141524654664 31831.63345283638 43855.31489126069 31526.44682523485 43668.65066597277 44577.258591644575 36903.03412947569 60304.35994115403 0.4348710790897096 0.6569683182681162 0.47645214297427174 0.5278496195614746 0.7272329054492149 0.5227888473735376 0.7241375367980913 0.7392045721925212 0.6119463694745498 1.0 15.879974690764254 -14.52287874306705 0.10938912226104512 2.2967362885315197 0.37491187365626666 0.6936679967722926 0.08756439826470984 92.81094918666878 0.673449307146519 26.798557439902712 1.07820778033109 3.0000000152888484e-15 14.52287874306705 -1.921824414875253 AQS(ph)MMSRR ddPTM_PC-9_AZD4547_30min_R2 1 AQSMMSRR 8 1 Q8IX29-2;Q8IX29 Q8IX29-2 FBXO16 F-box only protein 16 1 AQS(0.889)MMS(0.111)RR 52.278 0.033857 0.0 2005.3 1200.9 6705.5 8452.3 5907.1 2355.4 6631.5 7054.7 2047.6 6833.8 True False 2642.9436871688586 1589.067440120549 6616.580688704134 6503.752821733241 5087.001128968089 2208.116465651354 7221.690653082242 5964.558215878616 2155.831955741749 6594.550742046837 0.4007769127193847 0.24096674698227122 1.003340628879665 0.9862313713450306 0.7713946450564683 0.3348395595127367 1.0950997172615207 0.9044677111738044 0.3269111179926436 1.0 12.687058662971635 -5.252073135650349 24.82612069200135 0.79853168921599 0.32087177343383017 0.35738618673181843 0.25843468921768153 665.8172133907057 1764801.7120180645 0.06636840651507929 0.17045125447209286 5.5966334565926335e-06 5.252073135650349 -0.4776599157821599 AQS(ph)PGAVEEILDR ddPTM_PC-9_AZD4547_30min_R2 4 AQSPGAVEEILDR 13 0 H7BXT7;E9PHY4;A0A0C4DH16;B8ZZS0;Q9NYM9 H7BXT7 BET1L BET1-like protein 1 AQS(1)PGAVEEILDR;AQS(1)PGAVEEILDR;AQS(1)PGAVEEILDR;AQS(1)PGAVEEILDR 138.01 4.3707e-05 14445600.0 24933.0 35182.8 35359.0 30107.7 26310.4 27704.3 32362.4 35659.8 25101.199999999997 26760.1 True False 32861.17536138292 46554.952062847246 34890.11655683981 23166.834924328057 22657.655110562206 25971.945741421776 35242.590905724 30149.39729068399 26427.998186884553 25823.237044140515 1.2725428382666444 1.8028317667250362 1.3511132046381704 0.897131327289767 0.8774134347228709 1.0057587163463306 1.3647627075367301 1.1675297422685091 1.0234192615631534 1.0 14.656382239017589 -5.5571765042317445 5.8774192964949235 1.0616423594989632 1.5484992655288352 0.5632230575704418 0.17718368068764886 0.12307426786596504 11.767975661783334 0.05020063723098502 0.09011148130713413 2.7721932119616373e-06 5.5571765042317445 0.48685690602987197 AQS(ph)PGAVEEILDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AQSPGAVEEILDR 13 0 H7BXT7;E9PHY4;A0A0C4DH16;B8ZZS0;Q9NYM9 H7BXT7 BET1L BET1-like protein 1 AQS(1)PGAVEEILDR;AQS(1)PGAVEEILDR;AQS(1)PGAVEEILDR;AQS(1)PGAVEEILDR 181.51 8.193399999999999e-05 15283600.0 40339.0 45189.7 40249.3 30447.9 47745.7 27782.9 33761.5 25271.9 26968.6 22838.5 True False 47167.59596843304 49675.83476767695 41208.995958320265 28742.00287642367 38390.27283037525 26325.915814999797 30563.36630790713 24608.53940279142 27362.96475542137 26978.93926053346 1.7483117298622948 1.8412819825109275 1.527450562839713 1.0653496269391634 1.4229719137451422 0.975795065950241 1.132860191898545 0.9121388785952154 1.014234269597459 1.0 14.719546006054616 -5.523857660745201 0.7227812877677561 0.9995594849913053 2.0071112881315325 0.8210733697641323 0.1375942635952132 0.501853206474429 0.38160103385641214 0.06505067599693766 0.35396147333458955 2.9932455068256124e-06 5.523857660745201 1.007551803140227 AQS(ph)PGAVEEILDR ddPTM_PC-9_Lapatinib_30min_R1 4 AQSPGAVEEILDR 13 0 H7BXT7;E9PHY4;A0A0C4DH16;B8ZZS0;Q9NYM9 H7BXT7 BET1L BET1-like protein 1 AQS(1)PGAVEEILDR;AQS(1)PGAVEEILDR;AQS(1)PGAVEEILDR;AQS(1)PGAVEEILDR 168.05 0.00015352 12373000.0 36459.9 57990.8 40176.3 32566.4 41489.2 40294.0 32852.9 29685.3 41454.9 26634.3 True False 35939.975140073206 57856.525865544136 36873.15969900288 34961.4416943257 39048.886826905604 38570.71954990171 34553.86241152572 31064.587409515618 36785.812622550366 31238.003267026073 1.150520884220868 1.852119848089516 1.1803942583591798 1.1191957883950279 1.2500442647729815 1.2347370355331206 1.1061482424518398 0.9944485613876125 1.1775980784719489 1.0 14.93101461891846 -5.487107235590976 24.10853349971329 1.13582627734619 1.505054850029987 0.41391104281395363 0.17615794361962556 328.14568352013686 221155.7159683555 0.042935570212672455 0.08930880837481131 3.2575625563793247e-06 5.487107235590976 0.36922857268379694 AQS(ph)PGAVEEILDRENKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQSPGAVEEILDRENKR 17 2 H7BXT7;E9PHY4;A0A0C4DH16;B8ZZS0;Q9NYM9 H7BXT7 BET1L BET1-like protein 1 AQS(1)PGAVEEILDRENKR 47.485 0.032163 3147400.0 7005.1 7316.3 8527.1 11676.0 12958.0 10932.0 9241.6 10303.0 10099.0 7880.9 True False 8190.925072968344 8042.613912257773 8730.418403206837 11021.831574102745 10418.97291978132 10358.706675313877 8366.168744610117 10032.557166930856 10246.678769569073 9309.644784829927 0.8798321807417897 0.8639012656383216 0.937782117899177 1.183915372588955 1.1191590184793134 1.1126854906637682 0.8986560645410225 1.0776519833795286 1.100651958951865 1.0 13.184510406587838 -5.570535015645669 7.175591314128896 1.0701425332466945 0.878664916361701 0.5640560587603753 0.0726140785254122 0.15092823748729858 18.280471440103263 0.020927058533500274 0.03665645695283212 2.6882210924588066e-06 5.570535015645669 -0.19147761688499354 AQS(ph)PSYVISTGVSPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AQSPSYVISTGVSPSR 16 0 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 AQS(0.638)PS(0.362)YVISTGVSPSR;AQS(0.966)PS(0.034)YVISTGVSPSR 115.2 0.0019687999999999997 0.0 18956.199999999997 20922.8 22010.0 18030.0 24373.0 19775.5 15813.1 17381.5 15820.8 15023.3 True False 22165.11025798384 22999.877310031967 22534.801873389828 17019.837554048685 19597.285613044456 18738.43796722188 14315.168691070185 16925.254042221564 16052.149269986969 17746.905365622642 1.2489563561272863 1.2959936865716772 1.2697876846203155 0.9590312904365652 1.104264952638231 1.0558707324556946 0.8066290091792544 0.9537017126945022 0.9045041340605462 1.0 14.11527985470718 -5.915857960277325 0.8194539419142673 0.9247055324625229 1.3228427300485956 0.7179678504825964 0.08411244564395298 0.41146984641334944 0.5338518479630942 0.04101517400792587 0.11096131722268808 1.2137857645641597e-06 5.915857960277325 0.3981371975860728 AQS(ph)SPAAPASLSAPEPASQAR ddPTM_PC-9_AZD4547_30min_R2 2 AQSSPAAPASLSAPEPASQAR 21 0 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;Q8WUI4-10;H0YI15 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 AQS(0.5)S(0.5)PAAPASLSAPEPASQAR;AQS(0.5)S(0.5)PAAPASLSAPEPASQAR 246.32 2.8236999999999995e-61 81121900.0 33758.8 40041.7 57798.0 97028.0 60656.0 58506.0 52599.0 59854.0 44192.0 58081.0 True False 44493.39617333872 52984.396466879014 57031.5607554577 74659.69366765644 52234.9613987724 54847.610571197314 57280.209102235225 50604.93960809091 46527.898900243876 56047.60186848054 0.7938501325666968 0.9453463609595725 1.0175557714188395 1.3320765060180526 0.9319749580248812 0.9785897833755834 1.021992149399132 0.9028921474078194 0.8301496825756205 1.0 15.774365024721689 -7.766402219669248 23.27668177432954 0.8998905768915936 1.0103730964954274 0.0879086911322916 0.1329817640530563 122.693191341507 575419.957808047 0.07325491371121891 0.03703684982473632 1.7123706693349037e-08 7.766402219669248 0.11048251960383382 AQS(ph)SPAAPASLSAPEPASQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQSSPAAPASLSAPEPASQAR 21 0 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;Q8WUI4-10;H0YI15 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 AQS(0.952)S(0.048)PAAPASLSAPEPASQAR 166.59 1.0624e-31 0.0 8981.0 8486.0 12866.0 8457.4 11985.0 10454.0 11057.0 12532.0 10602.0 5479.5 True False 10501.305917164458 9328.433997979775 13172.774234576718 7983.559297260753 9636.625285042368 9905.773836784789 10009.600914252305 12203.048278751576 10757.034192986554 6472.889974301862 1.6223519878842192 1.4411544202071656 2.035068460436403 1.2333840570373398 1.4887670458328366 1.5303479398092477 1.5463882367831994 1.8852550139426314 1.6618595767413398 1.0 12.660194265921971 -11.549290508402457 2.6162661076318137 0.29319643006926555 1.6027675118325269 0.42013165709254907 0.21319966646432506 16446237.028699132 5234110.503944639 69812826.10890846 0.053861568684381446 2.8229909871692954e-12 11.549290508402457 1.3095710817632613 AQS(ph)SPAAPASLSAPEPASQAR ddPTM_PC-9_Lapatinib_30min_R1 2 AQSSPAAPASLSAPEPASQAR 21 0 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;Q8WUI4-10;H0YI15 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 AQS(0.762)S(0.236)PAAPAS(0.002)LSAPEPASQAR;AQS(0.5)S(0.5)PAAPAS(0.001)LSAPEPASQAR 201.85 1.0552999999999999e-19 145084000.0 74464.0 59344.0 73175.0 55193.0 59272.0 68681.0 65075.0 52176.0 73470.0 49071.0 True False 73402.12970497494 59206.59261408452 67158.83396366864 59252.07733845064 55785.7374932356 65743.67373323074 68444.26508557961 54600.2874378526 65195.03492660153 57552.85696700253 1.2753863765105433 1.0287342059844247 1.1669070399437098 1.0295245181733088 0.9692957123782735 1.1423181610414987 1.1892418325092284 0.9486981240419957 1.1327853796029723 1.0 15.812599926148865 -4.754172503349889 24.998878702943458 1.070890632196175 1.2753867339916987 0.3704412895552902 0.08119443288605152 286.9128694597299 986928.9903656907 0.019838738546316237 0.19869695262913936 1.7612763220846965e-05 4.754172503349889 0.20449610179552358 AQS(ph)SPASATFPVSVQEPPTKPR ddPTM_PC-9_AZD4547_30min_R2 5 AQSSPASATFPVSVQEPPTKPR 22 1 P56524-2;P56524 P56524-2 HDAC4 Histone deacetylase 4 1 AQS(0.752)S(0.248)PASATFPVSVQEPPTKPR;AQS(0.541)S(0.187)PAS(0.068)AT(0.187)FPVS(0.016)VQEPPTKPR;AQS(0.727)S(0.242)PAS(0.027)AT(0.003)FPVSVQEPPTKPR;AQS(0.742)S(0.256)PAS(0.002)ATFPVSVQEPPTKPR;AQS(0.8)S(0.198)PAS(0.002)ATFPVSVQEPPTKPR 181.49 7.8787e-14 368361000.0 145917.0 126725.9 189767.5 263195.5 231436.7 202666.9 155951.2 214116.8 181510.5 169159.6 True False 192315.57073785417 167687.56891495764 187251.05895811837 202519.84380493985 199305.70909323514 189994.10670481322 169830.55468249382 181029.96847458277 191104.77446896984 163237.37389217503 1.1781344317930922 1.0272621086499598 1.147108989157136 1.2406462991662222 1.220956355404766 1.1639130315237252 1.0403901424846118 1.1089982897798911 1.1707170356416194 1.0 17.316611880740837 -7.233034390199151 23.359270833023366 1.089109561620981 1.1622744492515065 0.2617452159246393 0.06757788057593045 545.5031357740903 448602.6611661969 0.02766061163460354 0.02141943793280691 5.8474377857981426e-08 7.233034390199151 0.07316488763052553 AQS(ph)SPASATFPVSVQEPPTKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AQSSPASATFPVSVQEPPTKPR 22 1 P56524-2;P56524 P56524-2 HDAC4 Histone deacetylase 4 1 AQS(0.743)S(0.256)PAS(0.001)ATFPVSVQEPPTKPR;AQS(0.761)S(0.238)PAS(0.001)ATFPVSVQEPPTKPR;AQS(0.785)S(0.215)PASATFPVSVQEPPTKPR;AQS(0.765)S(0.235)PASATFPVSVQEPPTKPR 173.34 4.5927e-13 357888000.0 102982.0 98675.0 117205.0 121084.0 131658.0 123169.0 118755.0 119704.0 104235.0 94064.0 True False 120414.81861278588 108470.80187964356 119999.6117024379 114300.05603962483 105860.56001486107 116709.80081336766 107505.66668825479 116561.89683687205 105759.23968175385 111117.05858978596 1.0836753612901573 0.9761849643634678 1.0799386991104933 1.0286454437350583 0.9526940449861038 1.0503319858765214 0.9674992125658811 1.0490009213363627 0.9517822107961684 1.0 16.76172078939706 -6.014390732361498 24.758777033917152 0.998277122551191 1.0420138494361404 0.23096888197716625 0.04240267950470801 943.8996668928712 1623952.5118693004 0.01142686711015081 0.015354949744018423 9.674070937577689e-07 6.014390732361498 0.04373672688494934 AQS(ph)SPASATFPVSVQEPPTKPR ddPTM_PC-9_Lapatinib_30min_R1 4 AQSSPASATFPVSVQEPPTKPR 22 1 P56524-2;P56524 P56524-2 HDAC4 Histone deacetylase 4 1 AQS(0.744)S(0.255)PAS(0.001)ATFPVSVQEPPTKPR;AQS(0.735)S(0.245)PAS(0.01)AT(0.009)FPVSVQEPPTKPR;AQS(0.735)S(0.238)PAS(0.017)AT(0.01)FPVSVQEPPTKPR;AQS(0.739)S(0.231)PAS(0.015)AT(0.015)FPVSVQEPPTKPR 154.71 3.6291e-06 314611000.0 153226.0 119297.1 161026.0 126085.0 124826.0 134613.0 119858.0 137147.9 145596.0 101485.9 True False 151040.96914179268 119020.87489454186 147787.06385833534 135357.71150722972 117483.98009735838 128855.91578822948 126063.6607703019 143520.29211702442 129197.44528615054 119027.6025935387 1.268957501039274 0.999943477824889 1.2416201001964717 1.137195982762552 0.9870313905132445 1.0825717142959939 1.0591128278101196 1.2057731903340485 1.0854410445225913 1.0 16.860936648869746 -4.7389161388809935 24.74088145487582 1.0971679580058764 1.268958286863626 0.2988232987808842 0.08190653887746124 2265.8183860803697 2488764.643144654 0.02018424076535464 1.0639129803230192 1.8242479257748578e-05 4.7389161388809935 0.17179032885774959 AQS(ph)TDSLGTSGSLQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AQSTDSLGTSGSLQSK 16 0 I3L456;Q15276-2;Q15276 I3L456 RABEP1 Rab GTPase-binding effector protein 1 1 AQS(0.979)T(0.021)DSLGTSGSLQSK;AQS(0.332)T(0.332)DS(0.332)LGT(0.004)SGS(0.001)LQSK 198.67 4.7642e-12 35916000.0 249417.0 339660.0 278676.0 268086.0 395100.0 322250.0 247912.0 282190.0 243668.0 270691.0 True False 291638.3718897009 373379.20006526134 285320.69272461603 253066.01056653904 317682.9912490808 305350.64271129685 224427.9806325508 274782.81150502025 247231.18352543423 319765.1355112234 0.9120393047961437 1.167667011190331 0.8922820565427202 0.7914121411702706 0.9934885200701641 0.9549216246577932 0.701852565239007 0.8593269903102856 0.7731649140866287 1.0 18.286653122551364 -5.438503004927464 8.317094869622295 0.8621677064269843 1.038874178013875 0.2837408005173674 0.10778181290249238 0.38423836506218034 34.64285845704843 0.02779004270657417 0.05797492644885885 3.6433172921167707e-06 5.438503004927464 0.1767064715868908 AQS(ph)YDIQAWK ddPTM_PC-9_AZD4547_30min_R2 2 AQSYDIQAWK 10 0 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 AQS(1)YDIQAWK;AQS(1)YDIQAWK 131.53 0.00017658 25536000.0 62835.0 71911.0 72166.0 87812.0 82143.0 108237.0 74616.0 94428.0 73187.0 82051.0 True False 82815.22295080798 95154.82445375044 71209.03168757318 67568.30008187586 70738.86234139002 101468.9232795729 81256.67944965458 79836.32233957296 77055.51540577815 79178.41946438084 1.045931751492756 1.2017772657934493 0.8993489914206639 0.8533676289442996 0.8934108917545717 1.2815224649087578 1.0262478084222009 1.0083091185659254 0.9731883501468768 1.0 16.272819648563605 -8.273012212066527 0.0037071331705364114 0.0001406046132068413 2.02666624575155 0.005874716147923897 0.12737229376510376 115562.8317815213 361.40850129062056 99053.42940097314 98491.41914303768 5.333198986826301e-09 8.273012212066527 2.026525641138343 AQS(ph)YDIQAWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AQSYDIQAWK 10 0 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 AQS(1)YDIQAWK;AQS(1)YDIQAWK 123.02 0.00049021 13687700.0 65508.0 69613.0 67705.0 71443.0 85120.0 66826.0 107806.0 78180.0 94460.0 76463.0 True False 76597.21055802348 76523.71858371038 69319.34397264247 67440.28033133109 68441.34703903264 63321.52691955037 97593.83523214996 76127.85783855729 95841.29879923709 90325.1366192251 0.8480165480504823 0.8472029099308643 0.7674424481068353 0.7466391179194395 0.7577220428412322 0.7010399240965312 1.0804726002637206 0.8428202899872945 1.0610700673862907 1.0 16.462839911324295 -7.257999636179611 24.9954159443029 0.9829924312678244 0.7783270665700047 0.6830025167897982 0.07256513214784724 186.29842523414197 1353772.2697742851 0.028231835478458298 0.02097064422276175 5.520779017713511e-08 7.257999636179611 -0.2046653646978197 AQS(ph)YDIQAWK ddPTM_PC-9_Lapatinib_30min_R1 2 AQSYDIQAWK 10 0 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 AQS(0.999)Y(0.001)DIQAWK;AQS(1)YDIQAWK 119.17 0.00081217 27731000.0 30707.0 42285.0 44301.0 41882.0 79863.0 99136.0 110594.0 95388.0 88280.0 77747.0 True False 30269.112549025856 42187.09168048267 40658.74278680529 44962.14199425629 75165.61535669917 94896.18437730311 116320.01617940194 99820.07471101456 78336.97677038774 91185.46535863425 0.33195106731074775 0.4626514929167713 0.4458906101635129 0.49308452632685806 0.824315750992456 1.0406941940151815 1.2756420743362225 1.0946928254236596 0.8590949935089639 1.0 16.476516261767017 -6.406513816849624 2.0078735514428336 1.0766845071762596 0.4179691064439383 0.8916534338841013 0.10223082849753672 0.10348509681874687 0.8248394695111364 0.03854071691580769 0.04520847695993501 3.9218066911326604e-07 6.406513816849624 -0.6587154007323213 down AQS(ph)YDIQAWKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AQSYDIQAWKK 11 1 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 AQS(0.999)Y(0.001)DIQAWKK;AQS(0.999)Y(0.001)DIQAWKK 69.878 0.015411000000000001 15994900.0 55789.0 37732.0 47827.0 81179.0 79025.0 100201.0 100254.0 105433.0 117761.0 92490.0 True False 65232.97581702344 41477.78359789927 48967.37706490752 76630.80381586908 63540.618535709174 94946.28316622086 90757.21534389548 102665.49546549762 119483.03184307569 109257.70484956288 0.5970560694721058 0.37963257286989605 0.4481823696766355 0.7013766573385571 0.5815664773774843 0.8690122430903391 0.8306710768715053 0.9396636658884415 1.0935890700577324 1.0 16.737375496554492 -6.8391985258759345 0.7012815083194747 1.0403149981380435 0.45533292110734036 0.8500024586169723 0.08825217561065961 0.2520671066287574 0.2689122453303679 0.06584926934924071 0.062080810794378924 1.4481097383562658e-07 6.8391985258759345 -0.5849820770307032 AQS(ph)YPDNHQEFSDYDNPIFEK ddPTM_PC-9_AZD4547_30min_R2 2 AQSYPDNHQEFSDYDNPIFEK 21 0 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 AQS(0.555)Y(0.445)PDNHQEFSDYDNPIFEK;AQS(0.934)Y(0.066)PDNHQEFSDYDNPIFEK 105.82 4.5498000000000004e-05 30691000.0 59865.0 62412.0 97299.0 125628.0 125682.0 111713.0 90851.0 119267.0 101860.0 104669.0 True False 78900.8247306457 82585.45846681981 96008.75168596274 96666.40553325186 108233.22372923553 104727.56845007621 98936.56299829244 100837.02563301004 107244.11164868866 101004.57016876407 0.7811609375577145 0.8176408090132101 0.9505386887498849 0.9570498183570926 1.0715675889555634 1.0368597012500678 0.9795256079302522 0.9983412182688953 1.0617748431531289 1.0 16.624061046727192 -5.323396832255679 1.3839739376467792 1.0211145870914073 0.7603991961863517 0.8854840852008364 0.03105478604651401 0.18127862482732046 0.5652003546726084 0.009933924174691654 0.04979541297472228 4.749010914893969e-06 5.323396832255679 -0.2607153909050557 AQS(ph)YPDNHQEFSDYDNPIFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AQSYPDNHQEFSDYDNPIFEK 21 0 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 AQS(0.979)Y(0.021)PDNHQEFSDYDNPIFEK;AQS(0.75)Y(0.237)PDNHQEFS(0.013)DYDNPIFEK 104.6 5.2196999999999995e-05 32041000.0 18512.4 23571.8 27948.0 28824.0 27459.0 29493.0 33470.0 25694.0 26947.0 23908.0 True False 21646.183683433388 25911.85252340085 28614.386313380233 27209.084728668855 22078.606066080807 27946.335160540817 30299.479298184364 25019.55972504333 27341.048896284563 28242.33114437612 0.7664446526307295 0.9174827811110295 1.0131736706542442 0.9634149741242938 0.7817557960500476 0.9895194209599003 1.072839176882815 0.8858886186534026 0.9680875405261641 1.0 14.785571554264402 AQS(ph)YPDNHQEFSDYDNPIFEK ddPTM_PC-9_Lapatinib_30min_R1 2 AQSYPDNHQEFSDYDNPIFEK 21 0 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 AQS(0.996)Y(0.004)PDNHQEFSDYDNPIFEK;AQS(0.816)Y(0.18)PDNHQEFS(0.004)DYDNPIFEK 130.15 1.3590999999999999e-05 29023000.0 68255.0 67033.0 74382.0 63013.0 69225.0 68208.0 53393.0 58322.0 75516.0 61738.0 True False 67281.67118356608 66877.78920699513 68266.59908282313 67647.18622520583 65153.32160158639 65290.90284061395 56157.42828604453 61031.8530349287 67010.59286126646 72409.33103928596 0.9291850955930273 0.9236073341253538 0.9427873190236329 0.9342329953097288 0.8997917901801524 0.9016918386552988 0.77555513191492 0.8428727645863161 0.9254414023644219 1.0 16.143888001950273 -6.616043390228994 2.3181179275777835 0.8713007882141185 0.9318505019328147 0.08510162558473411 0.055152141875228704 0.506800271530604 5.543193809184505 0.02017112348802205 0.020413103605046758 2.42078717454672e-07 6.616043390228994 0.06054971371869622 AQSAYLQPGPAALEGSGLAS(ph)ASSLSSLREPSLQPR ddPTM_PC-9_AZD4547_30min_R2 1 AQSAYLQPGPAALEGSGLASASSLSSLREPSLQPR 35 1 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 AQSAYLQPGPAALEGS(0.37)GLAS(0.377)AS(0.119)S(0.119)LS(0.008)S(0.003)LREPS(0.003)LQPR 59.426 0.00018887 9230400.0 18671.0 22618.0 38265.0 55984.0 46707.0 34477.0 36258.0 46347.0 32305.0 39502.0 True False 24607.98961907434 29928.826180903146 37757.58109809315 43077.75374417779 40222.53927150594 32321.14773977317 39484.89175894683 39185.136098108516 34012.57634803539 38119.047003473046 0.6455562652663455 0.7851409868189075 0.9905174464265342 1.1300847510760947 1.0551821840625042 0.8479002042424716 1.0358310310157897 1.0279673595863594 0.8922724732582241 1.0 15.218224431101877 -5.0902886087276284 2.7134022505617557 1.0020948368980305 0.654177789074346 0.7028247998288357 0.0759094902269261 0.16524461202622912 2.2158350595925844 0.021216118599871617 0.09258301888426533 8.122905322127745e-06 5.0902886087276284 -0.3479170478236845 AQSAYLQPGPAALEGSGLAS(ph)ASSLSSLREPSLQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQSAYLQPGPAALEGSGLASASSLSSLREPSLQPR 35 1 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 AQSAYLQPGPAALEGS(0.07)GLAS(0.302)AS(0.302)S(0.302)LS(0.012)S(0.012)LREPS(0.002)LQPR 69.756 4.8527999999999995e-06 4857200.0 3646.2 2189.9 4440.2 5618.6 7557.6 7383.7 6896.4 7702.7 7127.3 5441.9 True False 4263.429644267346 2407.2987994550913 4546.0712075522715 5303.808057746975 6076.7425326855455 6996.485773739028 6243.123066387771 7500.51228668527 7231.523278973126 6428.473391943305 0.6632102809370929 0.3744744129254883 0.7071774168420428 0.82504939110336 0.9452854763778633 1.0883588290973722 0.9711672874328406 1.1667641490257288 1.1249207763753475 1.0 12.650260457461938 -5.942528059575222 1.1530124908556154 1.0796285060683726 0.5042222813605688 0.8458288182663505 0.09188320056433114 0.17311278725595408 0.4652669309039209 0.03395685272954624 0.07223283524388599 1.1414895510990697e-06 5.942528059575222 -0.5754062247078038 AQSELAAHQK ddPTM_PC-9_Lapatinib_30min_R1 2 AQSELAAHQK 10 0 P25786;P25786-2;F5GX11;B4DEV8 P25786 PSMA1 Proteasome subunit alpha type-1;Proteasome subunit alpha type 0 ; 80.014 0.015305000000000001 5284600.0 50003.0 51934.0 60746.0 51687.0 58896.0 58485.0 48220.0 60528.0 66871.0 55176.0 False True 49289.948050572835 51813.750013815436 55751.69836634104 55488.234402777474 55431.85307399114 55983.73288519387 50716.59565772795 63340.35184832764 59339.28379715215 64713.09808260137 0.7616688044769229 0.8006686675343392 0.8615210833389281 0.8574498215485055 0.8565785708982218 0.8651066715077507 0.7837145363214114 0.9787871964880815 0.9169594032016525 1.0 15.981770126177329 -1.5228787479050283 0.04691896552761188 1.3269255423111812 0.045962845584750764 0.6512441464939315 0.04392804359567154 361.77406513734877 1.2898450844448708 8.701176607182335 34.42560194222127 0.029999999818692787 1.5228787479050283 -1.2809626967264305 AQSGSDS(ph)SPEPK ddPTM_PC-9_AZD4547_30min_R2 3 AQSGSDSSPEPK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AQS(0.002)GS(0.03)DS(0.484)S(0.484)PEPK;AQS(0.005)GS(0.139)DS(0.428)S(0.428)PEPK;AQS(0.307)GS(0.045)DS(0.324)S(0.324)PEPK 104.41 0.0019138999999999998 29967900.0 157285.0 138703.0 164313.0 214065.0 198292.0 184965.0 170358.0 164729.0 165678.0 200352.0 True False 207298.3582687644 183536.03226500162 162134.10225979303 164715.62152128134 170762.5785690677 173399.10931018242 185519.53197282393 139273.91814584154 174435.4008416592 193337.7374624023 1.0722084627119264 0.9493026797248686 0.8386055634447603 0.8519579451130849 0.8832345966719265 0.8968715139945337 0.9595619272667927 0.7203659253172219 0.9022315205047904 1.0 17.560763738142754 -4.8767567095791025 2.841731527140516 0.874245833732469 1.0876318543458237 0.39983612056170936 0.07088550616581314 0.3184389477667734 4.136907361792297 0.01772658282897111 0.14373381359282503 1.3281382683060303e-05 4.8767567095791025 0.21338602061335465 AQSGSDS(ph)SPEPK ddPTM_PC-9_Lapatinib_30min_R1 3 AQSGSDSSPEPK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AQSGS(0.012)DS(0.494)S(0.494)PEPK;AQSGS(0.005)DS(0.671)S(0.324)PEPK;AQSGS(0.011)DS(0.495)S(0.495)PEPK 164.92 0.00038496 43318000.0 427151.0 453940.0 440192.0 438153.0 465083.0 419595.0 398032.0 384315.0 457207.0 352418.0 True False 421059.7484101006 452888.9298199908 404001.1129502585 470376.2332555603 437727.7323283583 401649.89997371857 418640.14937446645 402171.6779108858 405711.53305684926 413332.9817325333 1.018693806250785 1.0956999558120286 0.9774228789022371 1.1380079839840593 1.0590196080979832 0.9717344555717675 1.0128399326366058 0.9729968226226138 0.9815609955834208 1.0 18.6569449619903 -6.753129043400922 24.813188567542298 0.9877020851772585 1.0598702123054644 0.41547025536109694 0.04144289939957549 160.13145197190914 478123.34737861715 0.013272821371696617 0.013061647643400795 1.765513149796482e-07 6.753129043400922 0.07216812712820586 AQSLLSTDREAS(ph)IDILHSIVK ddPTM_PC-9_AZD4547_30min_R2 1 AQSLLSTDREASIDILHSIVK 21 1 O00231-2;O00231;J3QRY4 O00231-2 PSMD11 26S proteasome non-ATPase regulatory subunit 11 1 AQS(0.041)LLS(0.012)T(0.004)DREAS(0.944)IDILHSIVK 54.103 0.0082054 1173100.0 2961.8 1198.8 4461.7 8267.7 6032.8 3980.0 3479.6 7646.9 4875.4 6010.9 True False 3903.5907907329215 1586.2886561882876 4402.534942777011 6361.70949969167 5195.249853708028 3731.12997082975 3789.2776591216125 6465.247313280822 5133.10369067363 5800.460220575569 0.6729794951245395 0.2734763442668491 0.758997523534461 1.0967594393846924 0.8956616641002518 0.643247230210212 0.6532718982676877 1.1146093701922306 0.8849476585435977 1.0 12.501951655868071 -5.468574372996646 6.825273428941847 0.885729683929617 0.4796985654595712 0.4817020765187483 0.17406092787005428 0.20863988471388997 21.548765677044518 0.0473018480038911 0.09805026584276007 3.399582829107759e-06 5.468574372996646 -0.40603111847004586 AQSLVISPPAPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 AQSLVISPPAPSPR 14 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 AQSLVIS(0.004)PPAPS(0.996)PR;AQSLVIS(0.001)PPAPS(0.999)PR;AQSLVISPPAPS(1)PR;AQSLVISPPAPS(1)PR 181.86 2.5663e-05 183015000.0 261183.0 472377.0 429877.0 632945.0 472382.0 371747.0 320418.0 381827.0 289619.0 405695.0 True False 344233.7610561126 625063.6274142939 424176.5501033576 487029.30915276887 406799.9132068534 348501.60132312786 348934.5812680843 322824.4106615848 304927.6690710927 391491.7415339481 0.8792874141031208 1.596620212128004 1.0834878621994513 1.2440346946898144 1.0391021573352341 0.8901888963420385 0.8912948710000477 0.8246008189002658 0.7788865938175887 1.0 18.578622348814726 -6.535601987148015 1.8896572088724413 0.8589293676601701 1.2273074603435652 0.42601832234534964 0.17555362874202904 0.29269881045471063 2.112668336714601 0.06254017649119312 0.06731439863737407 2.913385892117033e-07 6.535601987148015 0.36837809268339505 AQSLVISPPAPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AQSLVISPPAPSPR 14 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 AQSLVISPPAPS(1)PR;AQSLVISPPAPS(1)PR;AQS(0.243)LVIS(0.004)PPAPS(0.753)PR;AQSLVISPPAPS(1)PR 190.18 2.3164e-06 104855000.0 166636.0 188151.0 212168.0 283999.0 320578.0 240309.0 315109.0 286589.0 248236.0 154518.0 True False 194844.18358897814 206829.38783335956 217226.88977162127 268087.45676718134 257763.04218842866 227706.7730001829 285259.59432840126 279066.3424161458 251865.98188362631 182530.89023618525 1.067458682400881 1.133119920500762 1.1900828922191813 1.4687237673595437 1.4121612065491875 1.2474971918755366 1.5628017480180507 1.5288718641269365 1.3798540157105745 1.0 17.477781110590534 -5.614867002376873 4.299380789625971 1.3974463136950563 1.1121185726912908 0.34196965470270957 0.15297461790702327 0.2096635781943487 7.02985716301156 0.04075669792886929 0.07390747574505807 2.4273533299381727e-06 5.614867002376873 -0.28532774100376557 AQSLVISPPAPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 AQSLVISPPAPSPR 14 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 AQSLVISPPAPS(1)PR;AQSLVISPPAPS(1)PR;AQSLVISPPAPS(1)PR;AQSLVISPPAPS(1)PR 191.41 1.4035e-06 112106000.0 331709.0 419946.0 266346.0 161077.0 177715.0 196523.0 382773.0 329120.0 213952.0 135237.0 True False 326978.76883201866 418973.640838406 244448.06000529233 172923.13991712037 167262.15310113292 188118.1694074885 402591.1130173265 344412.1167116316 189854.4727455596 158612.53525802458 2.0614938680609485 2.6414913560068647 1.5411648241271343 1.0902236676049333 1.0545330028867987 1.186023343624546 2.538204892585616 2.1714054072167475 1.196970166555322 1.0 17.275147267168187 -8.445312016274343 6.143777625323724 1.0023938598176905 1.7620504292436923 0.20587652263313272 0.5446806726221215 0.37664322532065864 22.01563936558892 0.5898751919449061 0.15287236057523626 3.586641619353871e-09 8.445312016274343 0.7596565694260018 AQSNGSGNGS(ph)DSEMDTSSLER ddPTM_PC-9_AZD4547_30min_R2 2 AQSNGSGNGSDSEMDTSSLER 21 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 AQSNGSGNGS(0.609)DS(0.39)EMDTSSLER;AQSNGSGNGS(0.991)DS(0.009)EMDTSSLER 231.49 8.580999999999999e-109 21306000.0 31161.3 25636.8 37327.0 55462.0 52702.0 40628.0 28306.6 43364.0 33566.0 36815.0 True False 41069.94520469507 33923.39424505164 36832.019590971446 42676.092779358194 45385.23700273844 38087.524737404776 30825.832562849715 36663.09020558781 35340.23023365287 35526.11805561388 1.1560493364460107 0.9548860416425663 1.0367589144784481 1.2012596679589784 1.2775174853523465 1.0720992560397726 0.8676949312219768 1.0320038386460935 0.9947675729256426 1.0 15.116592433321726 -7.011867731041561 24.889156974696952 0.9753712042979248 1.121096781431177 0.38257986295417157 0.09090562340548365 665.4255887260904 1395538.5134844135 0.03683641147024776 0.030191140854091966 9.730435293081029e-08 7.011867731041561 0.14572557713325218 AQSNGSGNGS(ph)DSEMDTSSLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AQSNGSGNGSDSEMDTSSLER 21 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 AQSNGS(0.031)GNGS(0.967)DS(0.001)EMDTSSLER;AQSNGS(0.011)GNGS(0.985)DS(0.004)EMDTSSLER 177.32 2.4998999999999997e-41 0.0 23653.9 21992.7 18815.4 22440.5 24721.0 22233.0 24728.0 20022.3 22406.9 18292.5 True False 27658.03808417952 24175.98991130921 19264.030493801874 21183.23153808262 19877.09751118335 21067.062341040382 22385.58482478347 19496.735840380446 22734.55852280989 21608.785446649676 1.2799441297829974 1.1188037370724861 0.8914906643579386 0.9803064401922211 0.9198618571255788 0.9749304232324041 1.0359483127847073 0.9022596799119642 1.052097933913947 1.0 14.3993303652435 -4.967316371617389 3.2273603041043266 0.9676967979159273 1.2774338003537513 0.7835341449432125 0.05156465326178709 0.10671507757219882 2.140201009031759 0.012675867676742995 0.06654603356691557 1.0781610253522012e-05 4.967316371617389 0.309737002437824 AQSNGSGNGS(ph)DSEMDTSSLER ddPTM_PC-9_Lapatinib_30min_R1 3 AQSNGSGNGSDSEMDTSSLER 21 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 AQSNGS(0.006)GNGS(0.932)DS(0.061)EMDT(0.001)SSLER;AQSNGSGNGS(0.95)DS(0.05)EMDTSSLER;AQS(0.011)NGS(0.434)GNGS(0.551)DS(0.004)EMDTSSLER 217.18 4.8563999999999994e-32 29936000.0 106601.0 82746.0 85710.1 71713.7 79807.0 82971.0 63744.6 64626.7 93974.0 65068.2 True False 105080.85019177088 82554.406720899 78663.34642855362 76987.76472789004 75112.90916659888 79422.52374484768 67044.98348327687 67629.49241336765 83389.65852990958 76315.15167207348 1.3769329928518483 1.0817564390834946 1.0307697056879392 1.0088136240455472 0.984246345854875 1.040717629522989 0.8785278154378758 0.8861869619806544 1.092701209430013 1.0 16.21968189889028 -1.6101393214842725 0.9253844012634665 0.9744084559975696 199.99999999757205 0.7825753599877536 0.06142024233620755 385.1978170328687 0.909996672831731 0.0204380072803096 161881.80363635876 0.024539215724099273 1.6101393214842725 199.02559154157447 AQSPSYVISTGVSPS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 AQSPSYVISTGVSPSR 16 0 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 AQSPSYVISTGVS(0.385)PS(0.615)R 187.75 4.6377e-08 4184300.0 10010.0 10245.0 8871.5 7407.9 9453.0 7739.8 6621.9 8054.2 7337.1 5752.5 True False 9867.255564390824 10221.278331950927 8142.119514980318 7952.70167802997 8896.993125313062 7408.78679635502 6964.749580794457 8428.42753530268 6510.718534911778 6746.81196027556 1.4625063841245423 1.5149789844644581 1.2068099070968876 1.1787347453663373 1.3186958785419718 1.0981166868110583 1.0323023113438003 1.2492459527445372 0.96500666881575 1.0 12.719990237849444 -1.5228787452803378 0.24733758954905055 1.0072650570840378 4.26964512450542 0.7095559083867404 0.09622385528387264 27.309211955745877 0.3696995862272535 0.12507704367247707 36.93350968836513 0.02999999999999998 1.5228787452803378 3.262380067421382 AQSPVS(ph)GPNVAHLTDGATLNDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQSPVSGPNVAHLTDGATLNDR 22 0 Q5THJ4-2;Q5THJ4 Q5THJ4-2 VPS13D Vacuolar protein sorting-associated protein 13D 1 AQS(0.173)PVS(0.827)GPNVAHLTDGATLNDR 61.16 0.0037428000000000006 8608400.0 31464.0 35599.0 29304.0 40956.0 39278.0 41203.0 36936.0 30575.0 31525.0 25913.0 True False 36790.233757673144 39133.03345440515 30002.718496038873 38661.368101143555 31581.757859482208 39042.24214626396 33437.15468651739 29772.4386468903 31985.993485559455 30610.82177280486 1.2018701761988688 1.278405190976335 0.9801343694305445 1.2629967397834099 1.031718720061934 1.275439203692 1.0923311675423064 0.9726115446315985 1.0449243644277568 1.0 14.90175415527474 -7.536055989745078 6.25611256138527 1.0101610157478902 1.1672867320823732 0.3793525987040417 0.09516908284113312 0.16565019802768305 26.161217639291305 0.04208966418341888 0.02493370363130063 2.9103418892494853e-08 7.536055989745078 0.15712571633448302 AQSS(ph)PAAPASLSAPEPASQAR ddPTM_PC-9_AZD4547_30min_R2 2 AQSSPAAPASLSAPEPASQAR 21 0 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;Q8WUI4-10;H0YI15 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 AQS(0.311)S(0.688)PAAPAS(0.001)LSAPEPASQAR;AQS(0.08)S(0.9)PAAPAS(0.016)LS(0.003)APEPASQAR 200.2 2.566e-19 221070000.0 253270.0 230300.0 311500.0 429700.0 360970.0 276600.0 255730.0 363380.0 250300.0 295320.0 True False 333804.59165673744 304739.9712380403 307369.3064695154 330639.3037988213 310855.54629574844 259304.15827424798 278489.4745853467 307227.97064169555 263530.3470024225 284980.9366884125 1.1713225296248742 1.069334583496129 1.0785609382903443 1.1602155135040837 1.0907941770000786 0.9099000139709746 0.9772214163568305 1.0780649899316146 0.9247297382931853 1.0 18.120505890328445 -6.622212270768568 6.981453204786577 0.9832632385503683 1.1147177510798336 0.6351864201691722 0.051770236996398225 0.1539438388149709 9.394481569437271 0.017147746844177747 0.017127269870139402 2.3866444739677954e-07 6.622212270768568 0.13145451252946527 AQSS(ph)PAAPASLSAPEPASQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AQSSPAAPASLSAPEPASQAR 21 0 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;Q8WUI4-10;H0YI15 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 AQS(0.335)S(0.665)PAAPASLSAPEPASQAR;AQS(0.036)S(0.964)PAAPASLSAPEPASQAR;AQS(0.012)S(0.988)PAAPASLSAPEPASQAR;AQS(0.309)S(0.691)PAAPASLSAPEPASQAR 295.86 8.412699999999997e-132 254636000.0 143707.9 143602.9 143159.2 164895.3 179327.2 151607.4 166805.8 137216.3 150890.2 121356.6 True False 168034.80910959543 157858.84687349643 146572.6582622892 155656.75093877557 144189.32247107645 143656.84105442546 151004.7470545886 133614.51751768755 153096.68371878745 143357.5909216832 1.1721375061428974 1.1011544338781147 1.0224269068692873 1.0857935735249027 1.0058017963614332 1.0020874383478287 1.0533432243367082 0.9320365713363701 1.0679356616868982 1.0 17.12925877312142 -1.522878745363357 0.5171810109503526 1.006494026327969 7.018200766206184 0.6131998826833489 0.039454746743335614 72.38031202582671 0.7325837970812681 0.019720856597315782 476.66979099863255 0.02999999999426522 1.522878745363357 6.011706739878215 AQSS(ph)PAAPASLSAPEPASQAR ddPTM_PC-9_Lapatinib_30min_R1 1 AQSSPAAPASLSAPEPASQAR 21 0 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;Q8WUI4-10;H0YI15 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 AQS(0.335)S(0.665)PAAPASLSAPEPASQAR 161.97 2.5386e-06 118350000.0 55734.0 53990.0 68246.0 49992.0 44808.0 61384.0 47314.0 55400.0 55049.0 39829.0 True False 54939.222939636194 53864.98947213573 62635.07731717822 53668.578448423206 42172.48153591746 58758.74941309289 49763.68741081999 57974.086247643245 48848.801928331115 46713.38958119348 1.1760915538818957 1.1530952892748643 1.3408377743240176 1.1488906912897163 0.9027921526143297 1.25785668605707 1.0652981480679053 1.2410592930079998 1.0457130678437718 1.0 15.511548512218218 -14.522878202375802 0.05851336250252464 0.4434777171673536 1.3909677926357074 0.1786030537120843 0.1131481956448565 808.3896250375835 3.4490712643898513 65.23384032088369 11.30480208126134 3.0000037502540167e-15 14.522878202375802 0.9474900754683537 AQST(ph)DSLGTSGSLQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQSTDSLGTSGSLQSK 16 0 I3L456;Q15276-2;Q15276 I3L456 RABEP1 Rab GTPase-binding effector protein 1 1 AQS(0.038)T(0.717)DS(0.238)LGT(0.002)S(0.003)GS(0.001)LQSK 72.433 0.039807 5315200.0 29864.0 24922.0 30495.0 29398.0 32706.0 27929.0 23642.0 19147.0 19529.0 20888.0 True False 34919.38535911362 27396.09145623994 31222.11645293153 27750.925369601966 26297.494081985475 26464.354073805436 21402.458606742588 18644.411537923424 19814.57467976178 24674.82905068299 1.4151824633673424 1.1102849547596614 1.2653427664605161 1.1246653548278112 1.065761956363283 1.0725243129120245 0.8673802182289152 0.7556044866461741 0.8030278401954448 1.0 14.59075246915164 -6.6971928472462325 0.867520167252076 0.8245280962521023 1.2592633887781481 0.7320873607429323 0.09998831250945303 0.29623794609084003 0.4880722232551716 0.0605756392319975 0.06068415015260534 2.008200878627047e-07 6.6971928472462325 0.4347352925260458 AQSTDS(ph)LGTSGSLQSK ddPTM_PC-9_AZD4547_30min_R2 2 AQSTDSLGTSGSLQSK 16 0 I3L456;Q15276-2;Q15276 I3L456 RABEP1 Rab GTPase-binding effector protein 1 1 AQST(0.005)DS(0.549)LGT(0.352)S(0.094)GSLQSK;AQS(0.008)T(0.1)DS(0.81)LGT(0.059)S(0.021)GS(0.002)LQSK 197.1 4.0323e-50 5394600.0 22567.0 27982.0 40052.0 49888.0 46233.0 54695.0 36127.0 48187.0 34629.0 43110.0 True False 29742.83657724013 37026.63428216606 39520.88431048812 38387.09236191665 39814.34598967035 51274.91300365157 39342.233012727454 40740.80637710223 36459.41824349535 41600.732021662785 0.7149594521979112 0.8900476622114522 0.9500045405429015 0.9227504059766859 0.9570587836997145 1.2325483353742703 0.9457101137605161 0.9793290742068489 0.8764129012083202 1.0 15.34432129432762 -4.045198784083503 0.8656230442160175 0.9974872691286634 9.455660880411948e-14 0.4686813263066397 0.0887246054755997 6.572095952189118 1.5293364239752387 0.03213709020501545 8.442091880605997 9.011585673559531e-05 4.045198784083503 -0.9974872691285688 AQSTDS(ph)LGTSGSLQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQSTDSLGTSGSLQSK 16 0 I3L456;Q15276-2;Q15276 I3L456 RABEP1 Rab GTPase-binding effector protein 1 1 AQS(0.001)T(0.004)DS(0.759)LGT(0.219)S(0.012)GS(0.004)LQSK 98.572 0.0020322 4827700.0 22976.0 29108.0 29567.0 28869.0 28485.0 25630.0 22942.0 20358.0 21860.0 21539.0 True False 26865.38300331483 31997.64987192969 30271.98941347192 27251.56352456082 22903.56873128343 24285.917680963645 20768.767674303715 19823.624071084003 22179.66114494305 25443.850197369808 1.0558694063562741 1.257578928649618 1.1897566279729634 1.0710471612263257 0.9001612788009193 0.9544906723069034 0.8162588410637095 0.7791125917386992 0.8717100978387231 1.0 14.635029377229946 -6.174657696175384 1.8688288333608603 0.8658334543234264 1.1793254996487594 0.7391210652853684 0.07584288456597534 0.16332290811353037 1.1247848750977978 0.025868851297880132 0.03635890522514916 6.68870902993008e-07 6.174657696175384 0.31349204532533304 AQSTDS(ph)LGTSGSLQSK ddPTM_PC-9_Lapatinib_30min_R1 1 AQSTDSLGTSGSLQSK 16 0 I3L456;Q15276-2;Q15276 I3L456 RABEP1 Rab GTPase-binding effector protein 1 1 AQSTDS(0.593)LGT(0.378)S(0.027)GS(0.001)LQSK 191.4 1.4557e-08 7540700.0 21813.0 27638.0 27342.0 25250.0 23351.0 23468.0 18621.0 21154.0 21868.0 17196.0 True False 21501.942619985708 27574.005909073647 25094.04630317219 27106.969231530784 21977.54008983236 22464.328346579965 19585.104266747257 22136.89206647376 19404.99555975122 20168.3056877703 1.0661253827099668 1.3671949610419696 1.2442317511276504 1.3440379995810936 1.0897068117704676 1.113843110787533 0.9710832714432386 1.0976079205253804 0.9621529869768913 1.0 14.299802269721296 -6.53112973695494 2.307063000339422 1.0270444389061764 1.2616891133780799 0.5840526238468402 0.08942825329878733 0.20485393405035773 2.1944698052292817 0.03045441414921025 0.03255852953178857 2.9435421769765417e-07 6.53112973695494 0.2346446744719035 AQSTDSLGT(ph)SGSLQSK ddPTM_PC-9_Lapatinib_30min_R1 1 AQSTDSLGTSGSLQSK 16 0 I3L456;Q15276-2;Q15276 I3L456 RABEP1 Rab GTPase-binding effector protein 1 1 AQS(0.022)T(0.027)DS(0.312)LGT(0.369)S(0.27)GSLQSK 228.99 1.5325e-28 9871300.0 29870.0 28169.0 28082.0 23252.0 23799.0 27863.0 17367.0 22625.0 26863.0 14963.0 True False 29444.04832251287 28103.7764111982 25773.206359654778 24962.029646398158 22399.189610634243 26671.364441825353 18266.178282616376 23676.240096623274 23837.40606006939 17549.334613055762 1.6777871624037575 1.6014154969892989 1.4686144476657763 1.4223917998479412 1.2763554917900106 1.51979348675609 1.040847341814733 1.3491246602027533 1.358308254167975 1.0 14.099128711011316 -1.5228787452803516 0.13992525549900087 0.9836557518365581 3.3878727789385614 0.6640340997764749 0.12127282560699543 46.45832934281518 0.4346887057076328 0.5196843913285933 22.327819255596076 0.02999999999999903 1.5228787452803516 2.4042170271020034 AQT(ph)LPTSVVTITSESSPGK ddPTM_PC-9_AZD4547_30min_R2 1 AQTLPTSVVTITSESSPGK 19 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 AQT(0.999)LPTSVVTITSESSPGK 254.54 5.3578e-65 3262200.0 4738.5 9548.8 15250.0 15475.0 18586.0 27977.0 30453.0 28939.0 27854.0 34358.0 True False 6245.244433077165 12635.262863038643 15047.775035827015 11907.477836366657 16005.654717712747 26227.59376731253 33163.25800472193 24467.14250206405 29326.305574931986 33155.136877761295 0.18836430855654657 0.38109518020158456 0.45385953589352435 0.35914428223499695 0.4827503736969486 0.7910567181191343 1.0002449432493847 0.737959327155585 0.8845177048447812 1.0 15.0169447905792 -6.725764006806683 2.5097884002132385 0.8879419466276871 0.3575931929510134 0.8851368019249217 0.09339406403367491 0.09390099122899219 1.211477281459229 0.03533677860162165 0.03342749961019331 1.8803383045644546e-07 6.725764006806683 -0.5303487536766738 down AQT(ph)LPTSVVTITSESSPGK ddPTM_PC-9_Lapatinib_30min_R1 2 AQTLPTSVVTITSESSPGK 19 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 AQT(1)LPTSVVTITSESSPGK;AQT(0.998)LPT(0.002)SVVTITSESSPGK 243.99 3.2874000000000004e-53 10115700.0 54750.0 127143.0 115019.0 95325.0 105173.0 97901.0 98623.0 93578.0 88660.0 64598.0 True False 53969.25496007967 126848.60819514263 105562.58180617953 102335.5184948782 98986.93091807373 93714.00244837759 103729.21637395483 97925.97550328456 78674.17716881022 75763.67822857565 0.7123367848807027 1.6742667616063467 1.393313844764795 1.3507200400980597 1.306522244332364 1.2369251947568678 1.3691153703098784 1.2925187608743895 1.0384154915427115 1.0 16.209218753034072 -8.275281735690335 4.084298600930847 1.0046292087549598 1.3127865631209072 0.18664976803744893 0.22543113840976192 0.31964762464710367 12.250429736956626 0.1883734751444485 0.05442091508272129 5.305401603456497e-09 8.275281735690335 0.3081573543659475 AQT(ph)LPTSVVTITSESSPGKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQTLPTSVVTITSESSPGKR 20 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 AQT(0.937)LPT(0.031)S(0.031)VVTITSESSPGKR 89.92299999999999 0.00057989 13323000.0 33629.0 26141.0 29896.0 59959.0 79057.0 74416.0 81060.0 84631.0 93035.0 70345.0 True False 39321.72549697397 28736.105720149575 30608.834021211376 56599.69161970078 63566.34836542298 70513.49395811907 73381.40997642158 82409.52592395646 94395.46087007225 83097.99164928653 0.47319706188484745 0.34580987036882616 0.3683462549900769 0.6811198501472657 0.7649564941798296 0.8485583412860315 0.8830708001479314 0.9917150136644008 1.1359535771750835 1.0 16.342525989245097 -6.352345869474538 0.7247485873655367 1.0418877832762172 0.3363616126299888 0.9196102364337633 0.07436512420610865 0.1984043898370253 0.22821490567389466 0.04860722641178341 0.07779004316658392 4.4427730680640324e-07 6.352345869474538 -0.7055261706462284 down AQT(ph)PHEDGGPQPHR ddPTM_PC-9_AZD4547_30min_R2 1 AQTPHEDGGPQPHR 14 0 Q9BRZ2 Q9BRZ2 TRIM56 E3 ubiquitin-protein ligase TRIM56 1 AQT(1)PHEDGGPQPHR 94.639 0.0071212 2568800.0 9041.8 6882.8 10874.0 7549.0 8567.3 8326.6 12059.0 13730.0 8710.2 8145.0 True False 11916.904318876665 9107.530499510129 10729.803655054619 5808.694680887361 7377.878277362552 7805.936385706276 13132.227638621549 11608.343984012565 9170.60338977427 7859.84602914505 1.516175288254714 1.1587415918503425 1.3651417108258221 0.7390341565659395 0.9386797463976627 0.9931411323785642 1.6707996047156664 1.4769174791678783 1.1667662897935671 1.0 12.940285335674645 -7.229687429186406 24.9684455464762 1.3683641659587376 1.1061062735667608 0.12468813486273622 0.26327668545218597 1168.833682889134 919124.5621945095 0.1040519140816103 0.08059122311712169 5.8926761098532116e-08 7.229687429186406 -0.2622578923919767 AQT(ph)PHEDGGPQPHR ddPTM_PC-9_Lapatinib_30min_R1 1 AQTPHEDGGPQPHR 14 0 Q9BRZ2 Q9BRZ2 TRIM56 E3 ubiquitin-protein ligase TRIM56 1 AQT(1)PHEDGGPQPHR 120.59 0.00017722 3200600.0 21989.0 30922.0 26135.0 24002.0 29798.0 23544.0 24016.0 28231.0 27620.0 22486.0 True False 21675.432827711276 30850.40200884203 23986.281184017447 25767.18714832482 28045.34022512205 22537.078003744624 25259.430968809524 29542.715322332435 24509.144748505983 26372.67513928835 0.8218898050058101 1.169786600938448 0.9095126321972623 0.9770410856022145 1.0634241720644362 0.8545616963282692 0.9577879693812182 1.120201692331225 0.9293385907595625 1.0 14.686756299422258 AQT(ph)PPGPSLSGSK ddPTM_PC-9_AZD4547_30min_R2 4 AQTPPGPSLSGSK 13 0 Q9UQ35;Q9UQ35-2;I3L4D8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AQT(1)PPGPSLSGSK;AQT(0.998)PPGPS(0.001)LSGSK;AQT(0.979)PPGPS(0.021)LSGSK;AQT(0.968)PPGPS(0.032)LSGSK 116.58 0.00066486 738772000.0 275442.0 231607.0 290152.0 291563.0 283666.0 291926.0 236919.0 301133.0 234719.0 247974.0 True False 363026.8264504882 306469.4334282623 286304.394898051 224347.6549534459 244283.87233157805 273671.8210714688 258004.33202708105 254599.8141979353 247125.76715166442 239292.50573741147 1.5170839777525547 1.2807314315332872 1.1964620204705791 0.9375456797616329 1.0208588504633065 1.1436706729620008 1.078196457645034 1.0639690257467627 1.032735088757225 1.0 17.868415689095187 -4.975134627018999 1.446755180821465 1.0493703787696746 1.5988801726986208 0.8588941094519812 0.06050380656359099 0.30215939516168333 0.7601102115267064 0.018625867472613904 0.21757216066993093 1.0589254178267148e-05 4.975134627018999 0.5495097939289462 AQT(ph)PPGPSLSGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AQTPPGPSLSGSK 13 0 Q9UQ35;Q9UQ35-2;I3L4D8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AQT(0.99)PPGPS(0.008)LS(0.002)GSK;AQT(0.984)PPGPS(0.015)LS(0.001)GSK;AQT(0.999)PPGPS(0.001)LSGSK 104.9 0.0031488 585423000.0 113555.0 149098.0 118435.0 117534.0 124691.0 95622.0 117434.0 86128.0 85750.0 81238.0 True False 132777.61868651691 163899.4640856454 121258.9395672387 110948.95103036944 100258.69365183316 90607.4139870896 106309.80137146659 83867.23126015934 87003.9315269379 95965.80632034599 1.3835930085689943 1.707894409166201 1.2635640153166747 1.1561300351086283 1.0447335097373847 0.944163525127175 1.1077883409491818 0.87392827170336 0.9066138749098589 1.0 16.550232828720503 -5.716939465324789 1.472551175592226 0.9737896209717666 1.5556316141043032 0.812663069025083 0.10519367589892548 0.16230037724758328 0.7030868425195694 0.033307437112231636 0.08171349713218856 1.9189361953326117e-06 5.716939465324789 0.5818419931325366 AQT(ph)PPGPSLSGSK ddPTM_PC-9_Lapatinib_30min_R1 4 AQTPPGPSLSGSK 13 0 Q9UQ35;Q9UQ35-2;I3L4D8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AQT(0.986)PPGPS(0.013)LS(0.001)GSK;AQT(0.958)PPGPS(0.038)LS(0.004)GSK;AQT(0.992)PPGPS(0.007)LSGSK;AQT(0.998)PPGPS(0.002)LSGSK 132.51 0.00013511 737331000.0 120582.0 166555.0 154094.0 147754.0 181093.0 176766.0 174746.0 167392.0 175895.0 152066.0 True False 118862.4785679692 166169.35213060843 141424.9861400416 158620.32205289515 170441.46578253678 169206.13024167204 183793.4928412551 175169.64341454016 156083.85284353595 178350.40548479118 0.6664547705673997 0.9317015662449868 0.792961393923501 0.8893746084946327 0.9556550506248844 0.9487285985234336 1.030519063534891 0.9821656583196148 0.8751527781463103 1.0 17.444354970254054 -3.522391213349241 0.4702252422246551 0.9749940653611859 2.3589798630681447e-16 0.6194085678197236 0.0636552296797173 10.166757816821491 0.6918994089933798 0.03924508272060857 7.0950237596526256 0.00030033696422696754 3.522391213349241 -0.9749940653611857 AQT(ph)PPISSLPTSPSDEVGR ddPTM_PC-9_AZD4547_30min_R2 2 AQTPPISSLPTSPSDEVGR 19 0 Q15751 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 AQT(0.999)PPISSLPTSPSDEVGR;AQT(0.964)PPIS(0.033)S(0.004)LPTSPSDEVGR 156.29 3.9328e-05 11264600.0 46274.0 38541.0 56106.0 70732.0 59592.0 58529.0 55149.0 59567.0 46290.1 56687.0 True False 60988.16944100727 50998.62453966701 55361.99778099083 54425.83019850635 51318.67943279551 54869.17237756142 60057.15416223065 50362.288863486945 48736.90018288787 54702.40538417992 1.1149083666921384 0.9322921758467307 1.0120578316836075 0.9949440032164737 0.938143013499677 1.0030486226740907 1.097888726107085 0.9206594940348245 0.8909461995428579 1.0 15.739316652412432 -4.748831202079313 24.89024134891081 0.979271311393909 1.114908701892895 0.35222065371867495 0.05614354196115395 699.8644108487156 1381538.714288139 0.014435820737597778 0.25163395612917006 1.7830716620579843e-05 4.748831202079313 0.13563739049898593 AQT(ph)PPISSLPTSPSDEVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AQTPPISSLPTSPSDEVGR 19 0 Q15751 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 AQT(1)PPISSLPTSPSDEVGR;AQT(0.912)PPIS(0.06)S(0.017)LPT(0.004)S(0.004)PS(0.002)DEVGR 130.36 9.355e-05 7783400.0 18792.7 26158.5 26408.0 24113.5 25895.0 16883.0 14375.2 20241.7 17594.6 17320.4 True False 21973.932937256035 28755.343004496113 27037.66687289771 22762.4987720218 20821.06063881287 15997.625759177106 13013.476988564675 19710.376822853963 17851.887739287045 20460.45141178904 1.0739710720456024 1.4054109768041416 1.3214599389199677 1.11251205136688 1.0176246955536892 0.781880391454095 0.6360307857658742 0.9633402717350169 0.8725070322251554 1.0 14.320550354660318 -6.277994427817596 1.9206341782135765 0.8390709796826745 1.2743073468603974 0.6667726019693411 0.1265199008963046 0.19421012557371628 1.4087687931449822 0.04472809262329592 0.05785729777325253 5.272366260489598e-07 6.277994427817596 0.43523636717772285 AQT(ph)PPISSLPTSPSDEVGR ddPTM_PC-9_Lapatinib_30min_R1 2 AQTPPISSLPTSPSDEVGR 19 0 Q15751 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 AQT(0.994)PPIS(0.004)S(0.001)LPTSPSDEVGR;AQT(0.963)PPIS(0.023)S(0.008)LPT(0.006)S(0.001)PSDEVGR 99.01100000000001 0.0012776 11045600.0 33253.0 35203.0 37362.0 31557.0 27146.0 25189.0 22139.1 23732.0 25658.0 17178.3 True False 32778.806122146634 35121.489616365856 34290.24058149071 33877.80705106601 25549.325651089428 24111.725188426917 23285.354270551747 24834.675357925462 22768.125849281907 20147.546266354042 1.6269378756502233 1.743214243166572 1.7019561651909274 1.6814855071280417 1.2681110301633225 1.1967574050787995 1.1557414467605802 1.2326401949699861 1.1300694163092295 1.0 14.29831652575091 -6.330067054778443 2.875328924251306 1.1609362016868434 1.7013533957696112 0.9416851183839107 0.06443722036336635 0.05771524136090154 0.9382418102432427 0.02035085448993883 0.024310207570933575 4.67662928868161e-07 6.330067054778443 0.5404171940827678 AQTAPNKDVQR ddPTM_PC-9_AZD4547_30min_R2 1 AQTAPNKDVQR 11 1 P49588-2;P49588;H3BPK7 P49588-2 AARS Alanine--tRNA ligase, cytoplasmic 0 80.102 0.021442 1134700.0 1606.3 1514.3 4304.4 6249.0 5963.9 4262.3 4781.0 2574.1 3593.5 5702.7 False True 2117.0699868844267 2003.7678612495208 4247.320843555004 4808.389596087576 5135.915429407454 3995.777707202927 5206.499737975756 2176.331991933484 3783.4450737243496 5503.05020876679 0.3847084628651522 0.36411949468630356 0.7718121191750512 0.8737680765527879 0.9332852208445307 0.7261023533525717 0.9461116181861096 0.39547740059983766 0.6875178183359159 1.0 12.4260157762602 -5.265317195345898 10.96175008248286 0.7813675389239368 0.37426428592173305 0.5093381481300161 0.16359500755262682 0.14176361030497298 371.9219625988628 0.04393080440583345 0.0999691839197711 5.428537030019231e-06 5.265317195345898 -0.4071032530022038 AQTAPTKT(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 AQTAPTKTSPR 11 1 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 AQTAPT(0.023)KT(0.488)S(0.488)PR 101.32 0.038965 3939400.0 9539.5 6697.5 11597.0 16453.0 13069.0 8155.2 10788.0 11879.0 9116.7 11259.0 True False 12572.862566073572 8862.335898249126 11443.21620265481 12660.015046316033 11254.594937360796 7645.254054801701 11748.111100874803 10043.373502264041 9598.590149888067 10864.82583697289 1.1572079253482601 0.8156905624838172 1.053235125381731 1.1652294511002774 1.0358743992988388 0.7036701894277018 1.0812976919423873 0.9243934189986318 0.8834555007061562 1.0 13.407377427869898 -6.579885307607207 24.999861727270176 0.9179824852293063 1.040262070528891 0.20007255190078577 0.12667104858116798 146.32148888655374 64167.05484098928 0.04154501667990838 0.04154502183715818 2.630962708452574e-07 6.579885307607207 0.12227958529958471 AQTAPTKTS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 AQTAPTKTSPR 11 1 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 AQTAPT(0.002)KT(0.366)S(0.631)PR 104.7 0.010009 0.0 9807.9 6619.1 9269.1 6342.2 6460.7 7409.0 6352.8 6414.5 7208.4 4543.5 True False 9668.03754745142 6603.77388062629 8507.030377760704 6808.62654495899 6080.694328224909 7092.1343412225615 6681.716899510868 6712.541087283534 6396.514084182854 5328.837921166801 1.8142862835157332 1.2392521555957419 1.596413796705982 1.2776944327607125 1.1410920013295287 1.3308969884506583 1.2538788002859431 1.2596632111140955 1.200358160411506 1.0 12.379605238254522 -1.5228787452803376 0.4116217467886794 1.1860741005371316 10.13152785046959 0.5890683826623213 0.1411945906073695 57.31209427388669 0.7455961542593321 0.09445361010411706 419.5251360227308 0.029999999999999995 1.5228787452803376 8.945453749932458 AQTLPT(ph)SVVTITSESSPGKR ddPTM_PC-9_Lapatinib_30min_R1 3 AQTLPTSVVTITSESSPGKR 20 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 AQT(0.005)LPT(0.49)S(0.49)VVT(0.014)ITSESSPGKR;AQT(0.011)LPT(0.738)S(0.251)VVTITSESSPGKR;AQT(0.035)LPT(0.482)S(0.482)VVTITSESSPGKR 108.96 7.7803e-05 48916600.0 173615.0 128212.0 130640.0 111861.0 75292.0 98721.0 56003.0 63355.0 89074.0 52426.0 True False 171139.2182629082 127915.13299132153 119899.28348498358 120087.63109735688 70863.47258976745 94498.93295989091 58902.56131521645 66298.70458879843 79041.54812919693 61487.764246746076 2.783305269909287 2.0803347553507896 1.9499698021843206 1.9530329744216044 1.1524808790476966 1.536873784850484 0.9579558150601251 1.0782422389395456 1.285484178803587 1.0 15.908011729565562 -4.116813463755514 0.37239045102045665 0.994366785314156 5.036414139188683 0.8814469020459513 0.19540412595636794 3.1226269066568024 0.2352032603087257 0.1646498409989411 6.22251073286118 7.641639334118222e-05 4.116813463755514 4.042047353874527 up AQTLPTSVVTITSES(ph)SPGKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AQTLPTSVVTITSESSPGKR 20 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 AQTLPTSVVTIT(0.053)S(0.145)ES(0.401)S(0.401)PGKR;AQTLPTSVVTIT(0.001)S(0.057)ES(0.471)S(0.471)PGKR 144.58 2.1225e-05 175682000.0 212920.0 196930.0 182411.0 231010.0 260590.0 211870.0 231650.0 224320.0 196153.0 165141.0 True False 248963.1506383097 216479.90893497 186760.37003757025 218067.25864452528 209529.26016096745 200759.1642241815 209706.4349992352 218431.83768668683 199021.3665399827 195079.75604456302 1.2762121282407068 1.1096995061113284 0.9573539244887495 1.1178364329854458 1.0740697261949808 1.029113262671505 1.0749779436433728 1.119705304720544 1.0202051231523956 1.0 17.573704547773552 -4.810520334245973 3.7111396676719823 1.0557767638909634 1.2928538752854886 0.6608926491371925 0.04872579830536266 0.1430069603785271 3.398141329552758 0.011889295288089147 0.0885013790667403 1.5469620714280377e-05 4.810520334245973 0.23707711139452514 AQTLPTSVVTITSES(ph)SPGKR ddPTM_PC-9_Lapatinib_30min_R1 2 AQTLPTSVVTITSESSPGKR 20 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 AQTLPTSVVTIT(0.002)S(0.135)ES(0.431)S(0.431)PGKR;AQTLPTSVVTIT(0.011)S(0.082)ES(0.454)S(0.454)PGKR 128.09 8.8048e-06 37087000.0 80778.0 81588.0 80023.0 71843.0 81892.0 67875.0 64658.0 56065.0 65570.0 48837.0 True False 79626.09090712896 81399.08799875183 73443.8178377131 77126.57388122255 77075.27356586659 64972.144474352885 68005.67486597618 58669.984575345145 58184.81611728951 57278.41037878796 1.3901588815149288 1.4211129020594562 1.2822251412359675 1.346520850896117 1.3456252199766014 1.1343217111767852 1.187282859566942 1.0242949164851916 1.0158245616892543 1.0 15.805703834259472 -7.141934843897541 0.750911410993985 0.9861169007184444 1.385374293230692 0.9007185533650188 0.04897427601406165 0.19227739768921243 0.2192774736897737 0.03905312665374494 0.02690572421362204 7.212156732296087e-08 7.141934843897541 0.3992573925122477 AQTLPTSVVTITSESS(ph)PGKR ddPTM_PC-9_AZD4547_30min_R2 2 AQTLPTSVVTITSESSPGKR 20 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 AQTLPTSVVTIT(0.011)S(0.018)ES(0.054)S(0.917)PGKR;AQTLPTSVVTITS(0.001)ES(0.001)S(0.998)PGKR 198.73 5.1223e-16 1006700000.0 315260.0 281380.0 345560.0 422410.0 416150.0 378010.0 324160.0 379290.0 337750.0 413150.0 True False 415506.1221846388 372330.5823141981 340977.6486151067 325029.90066944354 358374.75577188 354372.97494305455 353009.61201887066 320679.44571712415 355602.7754697087 398685.74425307347 1.042189564523 0.9338948976260713 0.8552541783351666 0.8152533802741754 0.8988903188482071 0.8888528873962181 0.885433244372016 0.8043413900286505 0.8919375237153777 1.0 18.60489249446207 -4.8593692506080055 2.651987435620409 0.872246381608717 1.0610975343444877 0.47696991996580074 0.051178626110725364 0.3042530155627017 3.238237203818208 0.012653828318521715 0.11975446305061206 1.3823905279644169e-05 4.8593692506080055 0.1888511527357707 AQTLPTSVVTITSESS(ph)PGKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AQTLPTSVVTITSESSPGKR 20 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 AQTLPTSVVTITS(0.002)ES(0.244)S(0.754)PGKR;AQTLPTSVVTITS(0.011)ES(0.058)S(0.931)PGKR 179.66 5.545599999999999e-10 669800000.0 238661.0 186367.0 226176.0 220677.0 287607.0 221628.0 246977.0 223049.0 195474.0 216136.0 True False 279061.5935303841 204868.284103405 231568.8936172562 208313.18313448672 231252.4729541243 210005.43752620392 223581.55060136507 217194.20008995058 198332.43744952392 255319.7458683654 1.0929886859368068 0.8023989034088591 0.9069760461717113 0.8158913930686985 0.9057367348052688 0.8225193739401414 0.875692359166911 0.8506752948200446 0.7768002305304569 1.0 17.961945591362294 -4.753110670583011 24.99976608897336 0.8577363176137914 1.0929891219251844 0.558133695037508 0.06159866205229652 211.64283800049319 635226.2186335925 0.01381118898132 0.15360096472277993 1.765587841368942e-05 4.753110670583011 0.23525280431139295 AQTLPTSVVTITSESS(ph)PGKR ddPTM_PC-9_Lapatinib_30min_R1 2 AQTLPTSVVTITSESSPGKR 20 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 AQTLPTSVVTITS(0.018)ES(0.01)S(0.972)PGKR;AQTLPTSVVT(0.001)IT(0.059)S(0.022)ES(0.074)S(0.844)PGKR 259.81 9.399699999999997e-158 480300000.0 547797.0 449704.0 441287.0 436921.0 469272.0 337746.0 296316.0 296081.0 385021.0 310858.0 True False 539985.3143263331 448662.73801773036 405006.08627707994 469053.6278657301 441670.34358424967 323301.3909043801 311657.792594677 309838.00415683165 341655.8805291282 364589.3911077509 1.4810779674243062 1.2305973485803716 1.110855379106147 1.28652571716522 1.2114185282306205 0.8867547953660327 0.854818599213079 0.8498272624319505 0.9370977018586782 1.0 18.475913056606743 -6.725626836065981 4.746974720307142 0.8914738546734184 1.259678770740806 0.7807936167274152 0.09503662112380243 0.09295976282175991 4.824776834244216 0.0332474068207983 0.032125933296659887 1.880932298146879e-07 6.725626836065981 0.3682049160673875 AQTPESCGSLT(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 1 AQTPESCGSLTPER 14 0 C9JYJ6;Q4L180-6;Q4L180-5;Q4L180-3;Q4L180-7;Q4L180-2;Q4L180 C9JYJ6 FILIP1L Filamin A-interacting protein 1-like 1 AQTPES(0.007)CGS(0.236)LT(0.756)PER 120.32 0.0009096 0.0 13278.0 16427.0 19014.0 17151.0 22290.0 16973.0 19673.0 16784.0 21335.0 16342.0 True False 13088.65328511301 16388.96429077187 17450.742316162516 18412.34175405879 20978.94602382611 16247.104355995478 20691.571679271703 17563.84591300442 18932.027632490055 19166.69292565376 0.6828853227775374 0.855075226297176 0.9104722647695513 0.9606426014899366 1.094552206017071 0.847673848535939 1.0795587824948645 0.9163733139114469 0.9877566101740163 1.0 14.226313811425367 -4.546497115381764 1.0392579191085605 0.9834165523782075 0.40543215389087295 0.649669249138917 0.06813692028218767 1.6385721899379826 1.043899508815272 0.020646911863123733 1.1799350532801105 2.8412070564421502e-05 4.546497115381764 -0.5779843984873345 AQTPPGPSLS(ph)GSKSPCPQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQTPPGPSLSGSKSPCPQEK 20 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AQTPPGPS(0.147)LS(0.436)GS(0.106)KS(0.31)PCPQEK 67.88 0.0025198 219270000.0 106750.0 124590.0 102760.0 161930.0 182550.0 172860.0 146570.0 180270.0 138410.0 144570.0 True False 124820.66659139385 136958.47181337513 105210.18811947014 152857.58708414334 146780.63794614008 163794.9172973616 132685.82852509368 175538.10351185346 140433.98440400563 170779.39658450955 0.730888321938922 0.8019613287812605 0.616059022479373 0.8950587139971672 0.8594750940784958 0.9591023306860572 0.7769428349012498 1.0278646430571563 0.8223122180579459 1.0 17.381774408187304 -5.827611996801701 10.543343572401035 0.9021372377045231 0.7250064776387904 0.5163150268667153 0.08388363557109554 0.34660754814200784 53.26021552319591 0.022029932250939764 0.03272064283861056 1.487263785814754e-06 5.827611996801701 -0.1771307600657327 AQTPPGPSLS(ph)GSKSPCPQEK ddPTM_PC-9_Lapatinib_30min_R1 1 AQTPPGPSLSGSKSPCPQEK 20 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AQTPPGPS(0.119)LS(0.482)GS(0.119)KS(0.28)PCPQEK 54.728 0.011261 154520000.0 99736.0 91119.0 117680.0 109930.0 110090.0 100720.0 79091.0 76706.0 101850.0 83471.0 True False 98313.74635065768 90908.01955383486 108004.8046579366 118014.61891573004 103614.72264526757 96412.44038978763 83185.94498476491 80270.04078902041 90378.58047195278 97898.851131884 1.0042379988526602 0.928591280722677 1.1032285201430854 1.205475013764433 1.0583854810071618 0.9848168724667263 0.8497131888984206 0.8199283225590153 0.9231832593234386 1.0 16.579004309081597 -7.015466623135107 3.3354331247088234 0.8842115785500224 1.0622549113613071 0.4712718800408334 0.080000349439671 0.22119578702095197 5.118507420555125 0.03437222464342575 0.027689479315471166 9.650134732052861e-08 7.015466623135107 0.1780433328112847 AQTPPGPSLSGSKS(ph)PCPQEK ddPTM_PC-9_AZD4547_30min_R2 4 AQTPPGPSLSGSKSPCPQEK 20 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AQT(0.001)PPGPS(0.032)LS(0.034)GS(0.203)KS(0.729)PCPQEK;AQT(0.001)PPGPS(0.086)LS(0.302)GS(0.114)KS(0.497)PCPQEK;AQTPPGPS(0.071)LS(0.101)GS(0.101)KS(0.727)PCPQEK;AQTPPGPS(0.001)LS(0.001)GS(0.071)KS(0.927)PCPQEK 77.543 0.00092137 714397000.0 1378863.0 1141230.0 1689570.0 2138210.0 2164590.0 1937240.0 1641130.0 2120520.0 1780450.0 2192300.0 True False 1817312.7518679076 1510110.279530998 1667165.197854573 1645278.7195151898 1864074.0420431392 1816104.0765553308 1787187.3907099282 1792842.3587019918 1874560.952139285 2115548.244284183 0.8590268535723296 0.7138150990463275 0.7880534997766856 0.7777079648079056 0.8811304809897481 0.8584555239815994 0.8447868752407682 0.8474599260716071 0.8860875459607217 1.0 21.012600155512843 -10.969581435232353 0.121457698244794 1.254588525910475 0.6988604862072619 0.6674858872930383 0.04173332520465034 27.90768937249184 0.5807048776698245 2.643819424858135 0.5290926379397067 1.072552512992188e-11 10.969581435232353 -0.555728039703213 AQTPPGPSLSGSKS(ph)PCPQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AQTPPGPSLSGSKSPCPQEK 20 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AQTPPGPS(0.099)LS(0.072)GS(0.059)KS(0.77)PCPQEK;AQTPPGPS(0.008)LS(0.008)GS(0.062)KS(0.923)PCPQEK;AQTPPGPS(0.001)LS(0.005)GS(0.007)KS(0.986)PCPQEK 72.421 0.0015578 285275000.0 301081.0 316623.0 335514.0 445032.0 451851.0 422173.0 425892.0 427759.0 372702.0 341033.0 True False 352048.06667918904 348055.2389514912 343513.9262039314 420098.2998532117 363314.0401895431 400033.50468690874 385548.426568938 416530.77949812385 378152.06166708836 402859.5832842571 0.8738728859548675 0.863961671493623 0.8526889776419903 1.0427908812008848 0.9018378990209829 0.9929849537789094 0.9570293039222444 1.0339353878649584 0.9386696441083912 1.0 18.619917549419014 -5.744031976918624 24.999880234610007 0.9786471574559978 0.8635531730433013 0.6438579547057629 0.0400282709211769 145.38157128181257 208790.1299397477 0.01020104278980995 0.017616081056970857 1.8028849903147739e-06 5.744031976918624 -0.11509398441269658 AQTPPGPSLSGSKS(ph)PCPQEK ddPTM_PC-9_Lapatinib_30min_R1 2 AQTPPGPSLSGSKSPCPQEK 20 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 AQTPPGPSLS(0.001)GS(0.036)KS(0.962)PCPQEK;AQTPPGPSLS(0.001)GS(0.012)KS(0.987)PCPQEK 99.943 0.00015869 275390000.0 195786.0 172449.0 189514.0 191289.0 191648.0 160849.0 153605.0 155408.0 175201.0 132237.0 True False 192994.0557372445 172049.7049357346 173932.8904651955 205357.0311813979 180375.64143446521 153969.8632273327 161557.91530496278 162628.8230247969 155468.01843167987 155093.98925527325 1.2443683772914664 1.109325421068082 1.1214676423011778 1.3240811727616046 1.1630085878929854 0.9927519690908826 1.0416774762241132 1.0485823712814677 1.0024116290915117 1.0 17.242783249530063 -6.687967250910576 5.495749462734223 1.0218467567732632 1.1936746915564163 0.6881352462142596 0.059210329454877045 0.12964045718663372 6.938069635464476 0.02056850715362547 0.02036022690632656 2.051316857803038e-07 6.687967250910576 0.17182793478315306 AQTSTDAPTSAPSAPPS(ph)TPTPSAGKR ddPTM_PC-9_Lapatinib_30min_R1 1 AQTSTDAPTSAPSAPPSTPTPSAGKR 26 1 Q8IWZ8;B4DVK3;V9GZ08;Q8IWZ8-2 Q8IWZ8 SUGP1 SURP and G-patch domain-containing protein 1 1 AQTSTDAPTSAPSAPPS(0.498)T(0.498)PT(0.002)PS(0.001)AGKR 160.33 4.2346000000000006e-11 3926200.0 33215.0 20942.0 27957.0 21396.0 21173.0 22335.0 15452.0 13981.0 25138.0 16706.0 True False 32741.34800911499 20893.51008567264 25658.483377140838 22969.533214963645 19927.645767719623 21379.784115427967 16252.028952783332 14630.60830014984 22306.69372512467 19593.60984065424 1.671021740015506 1.066343070806752 1.309533239959834 1.1722971622771008 1.017048207542252 1.091161061657339 0.8294555768413049 0.746703053655442 1.1384677916185268 1.0 14.25809559744288 -1.522878745323228 0.4009453735108409 0.9254023321078325 11.322241472698902 0.6196008506525533 0.1501420697872358 49.147766588664076 0.650951566912435 0.10826612900473537 403.93604905711203 0.029999999997037233 1.522878745323228 10.39683914059107 AQTSTDAPTSAPSAPPST(ph)PTPSAGKR ddPTM_PC-9_AZD4547_30min_R2 1 AQTSTDAPTSAPSAPPSTPTPSAGKR 26 1 Q8IWZ8;B4DVK3;V9GZ08;Q8IWZ8-2 Q8IWZ8 SUGP1 SURP and G-patch domain-containing protein 1 1 AQTSTDAPTSAPSAPPS(0.256)T(0.743)PT(0.001)PSAGKR 159.1 1.1038e-10 5207400.0 12678.0 14440.0 18929.0 29048.0 26693.0 24090.0 16717.0 29043.0 22763.0 24879.0 True False 16709.340281218174 19107.447610409483 18677.98909201111 22351.432387126253 22987.137704718953 22583.64849178108 18204.78061487987 24555.071691746307 23966.20570841447 24007.99378257824 0.6959906951218705 0.795878563758838 0.7779904169071 0.9309995907840456 0.957478492909304 0.9406720401672731 0.7582799620720679 1.0227873230109323 0.9982594099889306 1.0 14.551227229979299 -3.276474957229417 0.3354770491044668 0.9789947805857854 1.1924983930312028e-13 0.5993942576667767 0.07121631905762138 14.250678150534123 0.5798887341689902 0.0699890748689487 6.919839089680312 0.0005290845049881198 3.276474957229417 -0.9789947805856661 AQTTNSNSSS(ph)SSDVSTHS ddPTM_PC-9_AZD4547_30min_R2 1 AQTTNSNSSSSSDVSTHS 18 0 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 AQTTNSNS(0.008)S(0.03)S(0.932)S(0.03)S(0.001)DVSTHS 168.47 9.8445e-08 1880300.0 605.35 523.06 3747.0 7117.6 4687.1 4519.0 947.06 4355.9 2759.8 4345.6 True False 797.8387079377998 692.1289160042093 3697.3123317536924 5476.7472858238025 4036.3770702351994 4236.426215623026 1031.3465053016764 3682.7957436242027 2905.6773937566327 4193.461866697695 0.1902577710969121 0.1650495313909348 0.8816849775398781 1.3060205290805902 0.9625405449111195 1.0102455561278694 0.2459415485549295 0.8782232581798494 0.692906597489778 1.0 12.033926021619134 -5.261441907723205 24.88990411406428 0.8691307456733056 0.17765358355385252 0.5403014144824323 0.2562451895592591 0.1623462324786324 1597111.0703986196 0.07117779090761402 0.1654586859607317 5.477193603240616e-06 5.261441907723205 -0.6914771621194531 AQTTNSNSSS(ph)SSDVSTHS ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQTTNSNSSSSSDVSTHS 18 0 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 AQTTNSNSS(0.001)S(0.707)S(0.286)S(0.005)DVSTHS 265.56 7.132699999999997e-173 0.0 0.0 900.04 2551.5 4159.2 5151.9 4863.3 2335.6 3369.6 3178.8 2729.0 True False 0.0 989.3900230428617 2612.3374366176363 3926.173508308333 4142.422178223596 4608.259986649648 2114.355059720329 3281.1515703863174 3225.283936301233 3223.7460972478875 0.0 0.3069069316245172 0.8103421788855484 1.2178916669833608 1.2849715992707933 1.4294736147439528 0.6558689784922436 1.0178070702241213 1.00047703479336 1.0 11.654522406112939 -5.246615524832817 2.1185668959265493 1.091029981768391 0.021930947897685012 0.7784011493747831 0.1989043524263351 0.17014834841723256 1.3894073627586148 0.06011240813789345 0.23468783011418284 5.667407951556317e-06 5.246615524832817 -1.069099033870706 down AQTTNSNSSSS(ph)SDVSTHS ddPTM_PC-9_Lapatinib_30min_R1 1 AQTTNSNSSSSSDVSTHS 18 0 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 AQTTNSNS(0.027)S(0.014)S(0.102)S(0.836)S(0.021)DVSTHS 234.82 5.343399999999999e-113 0.0 2940.3 901.72 3653.5 713.64 2116.5 2719.4 863.85 2369.6 3202.4 0.0 True False 2898.370782815018 899.6321227415119 3353.123332917837 766.1234662332527 1992.011631199101 2603.0976012310193 908.575926149488 2479.7002666500994 2841.711989233002 0.0 0.0 AQTTNSNSSSSS(ph)DVSTHS ddPTM_PC-9_AZD4547_30min_R2 1 AQTTNSNSSSSSDVSTHS 18 0 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 AQTTNSNSS(0.001)S(0.348)S(0.03)S(0.612)DVS(0.009)THS 278.19 9.003899999999999e-92 3310400.0 0.0 725.57 5018.8 9997.1 5463.8 4023.6 3300.9 5514.9 2775.2 3314.7 True False 0.0 960.0963132053186 4952.247432774335 7692.423048655321 4705.2456820531 3772.003655937331 3594.6737053093834 4662.698924794674 2921.8914063169104 3198.653361916159 0.0 0.30015641101859536 1.5482288552228998 2.4048942408836576 1.4710083118335817 1.1792473985607823 1.1238084589309758 1.4577068526117114 0.9134754772447572 1.0 11.643248940716454 -5.1990401953512775 4.760858166858934 1.4264925478009125 0.09436965954873495 0.605950793859546 0.3997220346484115 0.1456753096176127 6.7004009484916285 0.11103012915574098 0.31087535059052995 6.323533223336886e-06 5.1990401953512775 -1.3321228882521776 AQTVGLPVTMHS(ph)PNMRLLR ddPTM_PC-9_Lapatinib_30min_R1 1 AQTVGLPVTMHSPNMRLLR 19 1 Q9H0K1 Q9H0K1 SIK2 Serine/threonine-protein kinase SIK2 1 AQT(0.002)VGLPVT(0.133)MHS(0.866)PNMRLLR 49.902 0.030558 5493400.0 28718.0 24829.0 22261.0 22742.0 23391.0 22853.0 18529.0 21390.0 21923.0 19203.0 True False 28308.47605376379 24771.50997598923 20430.78650994498 24414.52254508802 22015.187368475377 21875.630462944933 19488.34095690671 22383.85748803411 19453.80088057555 22522.21296361089 1.2569136123302695 1.099870160006591 0.907139389142398 1.0840197002192693 0.9774877541583186 0.9712913423867077 0.8652942314502575 0.9938569324515171 0.8637606309827115 1.0 14.459060968724824 -1.5228787863950175 0.7038467842419969 0.9457973459483237 41.70276080120636 0.6773418885421116 0.06469012717372995 165.70955725475645 0.8655389706653462 0.024872551864306962 10635.608116662906 0.02999999715989866 1.5228787863950175 40.75696345525804 AQVLATIHGHAGAFPAAGDAGEGAPGGGS(ph)SPER ddPTM_PC-9_AZD4547_30min_R2 1 AQVLATIHGHAGAFPAAGDAGEGAPGGGSSPER 33 0 Q86WR7;D3DRR9 Q86WR7 PROSER2;C10orf47 Proline and serine-rich protein 2 1 AQVLATIHGHAGAFPAAGDAGEGAPGGGS(0.585)S(0.415)PER 91.869 4.2694e-12 107700000.0 12595.0 13839.0 24373.0 36285.0 28561.0 23409.0 17972.0 30178.0 22717.0 23021.0 True False 16599.94800772542 18312.186113605047 24049.79809496471 27920.05384766168 24595.798148746024 21945.23152943559 19571.473183622722 25514.683521451643 23917.77424232533 22215.041797047048 0.7472391076001478 0.8243147269720289 1.0825907200481408 1.256808522024612 1.107168664072261 0.9878546135507464 0.8810009615297809 1.148531871087598 1.0766477263844094 1.0 14.439249235294655 -5.192621165500964 4.141690536674859 1.0718965721057176 0.7681656109257146 0.5851724813700243 0.09553058999507237 0.16537370960232597 5.529110272501645 0.027215133123613445 0.07923860258651277 6.41769146866856e-06 5.192621165500964 -0.3037309611800031 AQVLATIHGHAGAFPAAGDAGEGAPGGGS(ph)SPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AQVLATIHGHAGAFPAAGDAGEGAPGGGSSPER 33 0 Q86WR7;D3DRR9 Q86WR7 PROSER2;C10orf47 Proline and serine-rich protein 2 1 AQVLATIHGHAGAFPAAGDAGEGAPGGGS(0.575)S(0.425)PER;AQVLATIHGHAGAFPAAGDAGEGAPGGGS(0.5)S(0.5)PER;AQVLATIHGHAGAFPAAGDAGEGAPGGGS(0.5)S(0.5)PER 82.50299999999999 1.0805e-08 113976000.0 58416.2 88976.0 100492.0 91663.0 107051.0 108462.0 104411.0 91188.0 106368.0 66315.0 True False 68304.90888745821 97808.94925810158 102888.11039803216 86527.4192854554 86075.12502203352 102774.0617835615 94520.43420982161 88794.4116216723 107923.43077151405 78337.38455074879 0.8719324659506432 1.2485603115168935 1.313397313276126 1.1045482279204881 1.0987745572010008 1.3119414488108427 1.2065814393967809 1.133487058967985 1.377674674619737 1.0 16.25741334140138 -6.727811127222052 24.99978413611245 1.2143204229599278 1.1432302692434546 0.06284632094097276 0.14348102442223754 639.440116587181 475368.32656175864 0.04662523978973389 0.046622563068660805 1.8714958688086875e-07 6.727811127222052 -0.0710901537164732 AQVLATIHGHAGAFPAAGDAGEGAPGGGS(ph)SPER ddPTM_PC-9_Lapatinib_30min_R1 1 AQVLATIHGHAGAFPAAGDAGEGAPGGGSSPER 33 0 Q86WR7;D3DRR9 Q86WR7 PROSER2;C10orf47 Proline and serine-rich protein 2 1 AQVLATIHGHAGAFPAAGDAGEGAPGGGS(0.5)S(0.5)PER 87.61 1.3428e-11 60557000.0 41288.0 49311.0 61732.0 47748.0 45837.0 41779.0 31223.0 43198.0 48399.0 32481.0 True False 40699.22554870811 49196.82340915882 56656.63325241115 51259.547202658665 43140.957779009295 39992.209561605785 32839.57416468768 45205.13678205224 42947.7949559356 38095.29757178803 1.0683530026773818 1.2914145982571918 1.487234300917207 1.3455610132999614 1.132448373653285 1.0497938619915792 0.8620374759589081 1.1866329878869222 1.1273778574639917 1.0 15.217325304077539 -6.433201454548651 3.5411681585878183 1.0478243346724945 1.3101452903418407 0.4781038338676331 0.12429097090494282 0.22658858517505331 5.3391898357724195 0.04336738365846974 0.04866816228816511 3.688064820092878e-07 6.433201454548651 0.2623209556693462 AQVLATIHGHAGAFPAAGDAGEGAPGGGSS(ph)PER ddPTM_PC-9_AZD4547_30min_R2 1 AQVLATIHGHAGAFPAAGDAGEGAPGGGSSPER 33 0 Q86WR7;D3DRR9 Q86WR7 PROSER2;C10orf47 Proline and serine-rich protein 2 1 AQVLATIHGHAGAFPAAGDAGEGAPGGGS(0.25)S(0.75)PER 94.152 1.6145e-15 94522000.0 24757.0 18500.0 45895.0 71603.0 56713.0 36630.0 33537.0 49027.0 33984.0 39395.0 True False 32629.21102241033 24479.76321278221 45286.4023127397 55096.0346053222 48839.378887638166 34339.52030942053 36521.72803022229 41451.003678381945 35780.32486028892 38015.793040904755 0.8583067302397587 0.6439366709104856 1.191252337259197 1.4492933120200653 1.2847128780159156 0.9032961714746137 0.9606988335328199 1.090362724612398 0.9411963291621858 1.0 15.214311266747917 -5.26418726610489 24.944457452532596 1.1125286364683207 0.7511216881864404 0.4114846747217421 0.16780103593457874 224.7482270283063 2040215.7022017296 0.048645968010202024 0.10910585822536904 5.4426791601190075e-06 5.26418726610489 -0.36140694828188025 AQVLATIHGHAGAFPAAGDAGEGAPGGGSS(ph)PER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQVLATIHGHAGAFPAAGDAGEGAPGGGSSPER 33 0 Q86WR7;D3DRR9 Q86WR7 PROSER2;C10orf47 Proline and serine-rich protein 2 1 AQVLATIHGHAGAFPAAGDAGEGAPGGGS(0.282)S(0.718)PER 68.45 2.0467e-05 10856000.0 3481.1 9044.6 7845.8 4583.7 7867.9 7848.2 8608.8 10294.0 9507.6 8059.3 True False 4070.381475140982 9942.488114320991 8032.873627362191 4326.890149555907 6326.241475192729 7436.626576033514 7793.312141685379 10023.793407394562 9646.630663387943 9520.387292616306 0.42754368599036235 1.0443365179095239 0.8437549209360652 0.4544867783805075 0.6644941304120212 0.7811264759996804 0.818591923012377 1.0528766424417084 1.0132603188180744 1.0 13.216804548717553 -7.548872786783391 2.123103844018575 1.0298183462754258 0.7089065523874639 0.4145075620043833 0.16889380615565622 0.34827463244111634 3.116717100428003 0.10325498806861373 0.052482575444589785 2.8257075578583762e-08 7.548872786783391 -0.32091179388796187 AQVLATIHGHAGAFPAAGDAGEGAPGGGSS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 1 AQVLATIHGHAGAFPAAGDAGEGAPGGGSSPER 33 0 Q86WR7;D3DRR9 Q86WR7 PROSER2;C10orf47 Proline and serine-rich protein 2 1 AQVLATIHGHAGAFPAAGDAGEGAPGGGS(0.37)S(0.63)PER 90.211 7.8363e-12 53759000.0 30611.0 27758.0 42468.0 30103.0 41203.0 33557.0 25823.0 31851.0 43970.0 21363.0 True False 30174.481526630098 27693.728056446438 38976.444971220706 32316.875040664174 38779.520548214765 32121.84533518765 27159.988587090615 33330.91373779218 39017.63557537318 25055.566085591796 1.2043025259757325 1.1052924512598308 1.5556002541740261 1.289808217873313 1.547740746137639 1.2820243304604209 1.083990219750372 1.330279811836266 1.5572442243805567 1.0 14.612843512792898 -5.207591230509119 24.99877402510603 1.3383543173263608 1.1547973125510147 0.13005742392859154 0.1812822683115672 624.4654532410179 289902.9697567789 0.04520552281003777 0.11960241760107329 6.200243839240589e-06 5.207591230509119 -0.1835570047753461 AQVPGPLT(ph)PEMEAR ddPTM_PC-9_AZD4547_30min_R2 2 AQVPGPLTPEMEAR 14 0 B8ZZS4;Q9H8Y5 B8ZZS4 ANKZF1 Ankyrin repeat and zinc finger domain-containing protein 1 1 AQVPGPLT(1)PEMEAR;AQVPGPLT(1)PEMEAR 150.37 0.00056999 6986200.0 21435.4 22896.0 34662.0 45145.0 33392.0 31879.0 28984.0 37518.0 28018.0 31118.0 True False 28251.411315982343 30296.684244316835 34202.35923225153 34737.51773329713 28756.09718787601 29885.601090472766 31563.519850552035 31720.455177872052 29498.97428011934 30028.56829158204 0.940817791965863 1.008928695838288 1.1389940039811868 1.1568156495504702 0.9576246495886804 0.9952389604552225 1.0511163750487662 1.0563425758384992 0.982363660953787 1.0 14.874048070965527 -6.296806124447577 24.99612451214214 1.0115378437776632 1.0631852115221057 0.14733097528704375 0.06337323145597444 1396.3889398200995 986920.357516216 0.02154030821894479 0.02442510873964785 5.048866362084606e-07 6.296806124447577 0.05164736774444245 AQVPGPLT(ph)PEMEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQVPGPLTPEMEAR 14 0 B8ZZS4;Q9H8Y5 B8ZZS4 ANKZF1 Ankyrin repeat and zinc finger domain-containing protein 1 1 AQVPGPLT(1)PEMEAR 87.363 0.02345 8192400.0 30891.0 35362.0 47941.0 50200.0 53464.0 46342.0 55180.0 43028.0 47944.0 41347.0 True False 36120.23617493901 38872.50566068358 49084.09525725493 47387.456750595906 42988.11299453528 43911.74393957151 49952.950931395666 41898.56059193445 48645.09029886317 48842.8837973281 0.739518909751904 0.7958683566266016 1.0049385179820203 0.9702018608735014 0.8801305257263885 0.8990407716665915 1.0227273053465424 0.8578232351265564 0.995950413180236 1.0 15.575860762456271 -5.123706181928726 4.676328808708683 0.9468236434667402 0.7521112238240358 0.6512877967827178 0.05483206016029519 0.12843722344714734 4.226903377166556 0.01378567458380143 0.04040109440053055 7.521315698566102e-06 5.123706181928726 -0.19471241964270436 AQVPGPLT(ph)PEMEAR ddPTM_PC-9_Lapatinib_30min_R1 2 AQVPGPLTPEMEAR 14 0 B8ZZS4;Q9H8Y5 B8ZZS4 ANKZF1 Ankyrin repeat and zinc finger domain-containing protein 1 1 AQVPGPLT(1)PEMEAR;AQVPGPLT(1)PEMEAR 153.41 0.00059659 9033900.0 53422.0 54889.0 63206.0 47807.0 48350.0 58536.0 54010.0 49116.0 66779.0 42755.0 True False 52660.19248360502 54761.90789287011 58009.446662215654 51322.88625947691 45506.14805975741 56032.55173408069 56806.37352704036 51398.10866677344 59257.64580595507 50145.144782543546 1.050155358249898 1.09206799841435 1.1568307742210333 1.023486650243821 0.9074886164372776 1.1174073178384094 1.132838957258644 1.0249867437747646 1.181722499016171 1.0 15.613822400681222 -10.306415300233716 15.084868500722608 0.99997959235621 1.0740018177809236 0.08301241782135538 0.07575366287649807 0.0 0.0 0.07524428270581725 0.018249419136465928 4.9383822134611784e-11 10.306415300233716 0.0740222254247136 AQVSPQS(ph) ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AQVSPQS 7 0 A9Z1X7;Q8IYB3;Q8IYB3-2 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 AQVS(0.084)PQS(0.916) 88.134 0.023481000000000002 11491000.0 25113.0 33447.0 33894.0 33069.0 40086.0 34962.0 32146.0 31751.0 34487.0 25620.0 True False 29364.134895640884 36767.39711647767 34702.16150371081 31216.25114114453 32231.436059758733 33128.53117291655 29100.898163114263 30917.56989296532 34991.307132006 30264.703192191577 0.9702436104913448 1.214860654108903 1.1466215704591518 1.0314408485327045 1.0649843765219738 1.094626005830576 0.9615457973703975 1.0215718851306028 1.1561754599012193 1.0 14.885348582067806 -5.766091936055561 24.998201743775 1.0472400445554744 1.1210038196906371 0.12436256057271344 0.07556773903558586 205.28057023994404 1102980.6238775898 0.02077068114706333 0.03199627341406475 1.7135945172739687e-06 5.766091936055561 0.07376377513516275 AQYDELAR ddPTM_PC-9_AZD4547_30min_R2 2 AQYDELAR 8 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ; 167.23 0.0021114000000000003 222090000.0 312280.0 272560.0 378330.0 504180.0 468470.0 377910.0 310070.0 483470.0 350910.0 383530.0 False True 411578.5441724889 360659.6897986988 373313.09700356895 387949.09050334967 403431.02688081784 354279.22795886174 337665.6293148176 408760.8205353649 369458.3862030361 370102.7314374459 1.1120656758569565 0.974485350048428 1.0086742552632733 1.048220014471631 1.0900514711521523 0.9572456452371289 0.9123564908676964 1.1044523204348544 0.9982590097838316 1.0 18.49756625751271 -6.769965774740869 24.99790523131675 0.9958593361459305 1.040659442473294 0.1661270498200178 0.05768599377445202 437.58618824512274 1282918.4032211683 0.02093569059489086 0.01874682258763807 1.6983774904951204e-07 6.769965774740869 0.04480010632736353 AQYDELAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AQYDELAR 8 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ;;; 136.27 0.016084 172308000.0 491763.0 520811.0 607502.0 610361.0 682020.0 587538.0 595032.0 556102.0 530568.0 449136.0 False True 575008.7631380181 572513.6741600106 621987.1516441661 576164.4519870603 548383.0769215359 556726.472978463 538666.2613013819 541504.9117387737 538326.55326396 530560.8014413813 1.0837754345512982 1.0790726955415013 1.172320212790703 1.0859536747188765 1.033591391282086 1.0493170084672616 1.0152771554890228 1.0206274384908578 1.0146368744194472 1.0 19.017158565655265 -6.2222760245856055 3.139389472850387 1.0229922140130274 1.1109296428226816 0.7071639236482412 0.0265280438260298 0.14848726440108323 2.9656945400743364 0.008635204912342652 0.011069530134857368 5.994099881004708e-07 6.2222760245856055 0.08793742880965416 AQYDELAR ddPTM_PC-9_Lapatinib_30min_R1 2 AQYDELAR 8 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ; 129.42 0.016266 377650000.0 513690.0 560980.0 634690.0 541840.0 584620.0 614960.0 554870.0 455730.0 561610.0 500780.0 False True 506364.6864007925 559681.0852765098 582508.2381742506 581688.721125254 550233.8010071429 588659.5943417773 583598.4536002394 476904.8795241611 498355.56778452004 587339.1557525926 0.862133371223918 0.9529095409267531 0.9917749097246005 0.9903796050850748 0.9368246533846285 1.0022481705438022 0.9936311037401209 0.8119752869414513 0.848497095593682 1.0 19.163834294678182 -7.749129779040803 24.999992634320485 0.8726771306983585 0.963993886629741 0.23702619604779895 0.05960441230798479 248.83327115629456 505366.25194097054 0.02775452424072304 0.015878508486216112 1.7818462236139173e-08 7.749129779040803 0.09131675593138244 ARAT(ph)VAPLPMT(ph)PVPGRAS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ARATVAPLPMTPVPGRASK 19 2 Q8TC57-3;Q8TC57-4;Q8TC57 Q8TC57-3 M1AP Meiosis 1 arrest protein 3 ARAT(1)VAPLPMT(1)PVPGRAS(1)K 42.277 0.044961 0.0 10925.0 11744.0 10707.0 16130.0 15994.0 15780.0 16213.0 12477.0 11431.0 10156.0 True False 12774.386721414277 12909.86670660789 10962.295486523624 15226.288394165565 12860.09051388968 14952.469020897643 14677.187268044909 12149.491970474253 11598.156749672642 11997.202405148237 1.0647804621461197 1.0760730935962213 0.9137376461882052 1.2691532475630871 1.071924110271838 1.246329645524797 1.2233841501037472 1.0126937564428076 0.9667384410131852 1.0 13.550410406486304 -7.936214409384602 9.468561534185177 0.9854513757679512 1.1219795355042044 0.2678339022294971 0.09960950855350802 0.4647017525542694 64.7020735270163 0.05697469633747455 0.027303733375646982 1.1582054137745006e-08 7.936214409384602 0.1365281597362532 ARDQADQECGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ARDQADQECGR 11 1 Q92817;K7EKI0 Q92817 EVPL Envoplakin 0 92.11200000000001 0.010143000000000001 523430.0 680.44 567.35 897.93 649.7 2178.1 2528.4 492.2 844.16 613.47 765.25 False True 795.6250526974031 623.6727585144739 919.3400566184885 613.2994153558197 1751.3169406216762 2395.806253006183 445.57525278058966 822.0016944614533 622.4408381787838 903.9837672843333 0.8801320128651737 0.689915882436756 1.0169873507577323 0.678440739260439 1.9373322884799413 2.6502757457730115 0.4929018295529208 0.9093102378716786 0.6885531142319784 1.0 9.82015305636579 -6.161134952515929 24.102178269001318 1.3048629891363455 0.8216628020639432 0.12504348825388156 0.5981750028180346 72.53032416434891 17412.14467750833 0.19366439065670588 0.25001965925982794 6.90025352285213e-07 6.161134952515929 -0.4832001870724023 AREELSR ddPTM_PC-9_AZD4547_30min_R2 1 AREELSR 7 1 P42566;P42566-2 P42566 EPS15 Epidermal growth factor receptor substrate 15 0 79.45100000000001 0.034803 582370.0 2622.4 462.89 2502.8 3626.0 2401.4 1876.5 1808.4 958.23 2468.1 2217.1 False True 3456.2686506914765 612.5101401926897 2469.6112366995303 2790.0817211415524 2068.0070611812853 1759.1621583572937 1969.3440966649976 810.15757143484 2598.5587272739854 2139.480003832719 1.6154713502812967 0.2862892567798827 1.1543044255031156 1.304093385375572 0.9665933112142225 0.8222381864779693 0.9204779166606205 0.3786703170786841 1.2145749072760021 1.0 11.063044479862711 -6.626473263586802 4.610839023412485 0.8326575937029759 1.0476853577344876 0.06572045376969526 0.36986440431828504 0.6439257035916267 23.455903231634867 0.12127543849105833 0.12103394322368687 2.3633428888382776e-07 6.626473263586802 0.2150277640315117 AREELSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AREELSR 7 1 P42566;P42566-2 P42566 EPS15 Epidermal growth factor receptor substrate 15 0 79.45100000000001 0.042654000000000004 0.0 1283.1 1186.0 2110.2 1024.6 2538.1 2662.8 2701.4 2353.8 1162.3 846.27 False True 1500.3034876198328 1303.7382419990595 2160.515170978065 967.1949837980187 2040.7775249033004 2523.1580804085065 2445.5038355576694 2292.015244057249 1179.2964386444323 999.6920519303662 1.5007656455033382 1.3041398493481988 2.1611807024034997 0.9674929213755407 2.0414061719933043 2.5239353214186178 2.4462571557266033 2.2927212831506036 1.1796597125757446 1.0 9.96533994108829 -6.399166524624245 19.899270045459087 2.035916096691165 1.5170734225152451 0.10353569098247983 0.5514853681293905 6.857455860840645 1075.3717227904456 0.16825856584633947 0.1907868808703357 3.9887193073318313e-07 6.399166524624245 -0.51884267417592 AREELSR ddPTM_PC-9_Lapatinib_30min_R1 1 AREELSR 7 1 P42566;P42566-2 P42566 EPS15 Epidermal growth factor receptor substrate 15 0 92.47 0.018879 499400.0 1338.8 1168.5 2127.6 2304.3 2140.1 2411.4 2490.3 2371.9 1240.9 2184.6 False True 1319.7084664941485 1165.7944100424259 1952.6769407735028 2473.765908919461 2014.2235255984854 2308.270043247953 2619.2355488685193 2482.1071330466607 1101.1367747437034 2562.205199203475 0.5150674375746379 0.45499650473148756 0.762107945679191 0.9654831352650804 0.7861288885935666 0.9008919519660392 1.0222583069001554 0.9687386216444668 0.42976135365193197 1.0 11.323170306016301 -5.3809602578347615 3.695886726779334 0.8706030643882061 0.484085643046169 0.4610821481858359 0.16259648572063018 0.19849926088862133 4.7984904438864815 0.04312685958562994 0.09918387314719344 4.159486720978629e-06 5.3809602578347615 -0.3865174213420371 AREES(ph)WGPPR ddPTM_PC-9_AZD4547_30min_R2 2 AREESWGPPR 10 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 AREES(1)WGPPR;AREES(1)WGPPR 84.169 0.0059995 14152300.0 18396.4 13489.1 20768.5 33518.0 28672.0 21960.7 20413.4 23474.0 18014.9 23813.0 True False 24246.072531109152 17849.187781272467 20493.096120103168 25790.94294793782 24691.387714745484 20587.49395738715 22230.153054004226 19846.6326788573 18967.130835852728 22979.3141181131 1.055126032329988 0.7767502410876186 0.8918062573482031 1.1223547759246868 1.0745049912209028 0.8959142057751569 0.9673984584457915 0.8636738493083869 0.8254002159665058 1.0 14.488048116908402 -10.396892967399054 7.467591169852267 1.0000000002284086 0.9415055841568373 0.026093365077314634 0.1073342792561862 4.715230797441948e-10 0.0 0.10966427280135102 0.026597492948030606 4.009655240748783e-11 10.396892967399054 -0.058494416071571353 AREES(ph)WGPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AREESWGPPR 10 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 AREES(1)WGPPR 75.102 0.01178 5975300.0 10254.0 6938.3 10218.0 8605.8 10815.0 8705.5 10760.0 8223.0 9142.8 8356.0 True False 11989.799674268384 7627.088570372745 10461.635871980794 8123.64492638004 8695.878386127102 8248.968254843116 9740.734904346094 8007.154962988681 9276.49615352174 9870.876653940393 1.2146641169386034 0.7726860377014293 1.0598487083520158 0.8229912307877062 0.8809631293139258 0.8356875021379361 0.986815583442394 0.8111898510850375 0.9397844263223186 1.0 13.268962503905906 -4.746941816910771 24.994317330939186 0.8977311132410561 1.214664937715074 0.5271230787400277 0.08904374614887263 567.7838719100845 978824.5828879548 0.02022088135943979 0.4345986148111067 1.790845760282343e-05 4.746941816910771 0.31693382447401786 AREES(ph)WGPPR ddPTM_PC-9_Lapatinib_30min_R1 2 AREESWGPPR 10 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 AREES(1)WGPPR;AREES(1)WGPPR 73.273 0.013392 20361000.0 21678.9 15859.5 19137.9 16154.6 16982.0 16086.6 16469.9 11856.4 18576.0 11957.7 True False 21369.754910576637 15822.778302154771 17564.45573643036 17342.66317416582 15983.152147896593 15398.61361769615 17322.630834160387 12407.29162791621 16483.775266048044 14024.572512366296 1.5237366338071023 1.128218224705451 1.2524057842720508 1.2365912158016772 1.1396534285664182 1.097973831581553 1.2351628414260754 0.8846823400125718 1.1753495695867608 1.0 13.77566917578897 -1.5228787452803376 0.2913810970274735 1.0380565297731046 4.063581615505365 0.523235510193922 0.11106265484886928 44.24950482672377 0.6283697676573122 0.11286281057864785 69.08958749892591 0.029999999999999995 1.5228787452803376 3.0255250857322604 ARFEELCSDLFR ddPTM_PC-9_AZD4547_30min_R2 2 ARFEELCSDLFR 12 1 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;P17066;P48741 A0A0G2JIW1;P17066 HSPA1B;HSPA1A;HSPA6;HSPA7 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7 0 ; 135.1 7.6961e-05 18087600.0 26971.1 23104.6 37528.0 58099.0 51373.0 35697.0 29467.0 43232.0 31180.0 36795.0 False True 35547.3487662694 30572.710114921523 37030.3541996404 44705.17317060205 44240.745712528595 33464.86094691195 32089.50591485705 36551.48777252959 32828.111144768394 35506.81824952637 1.0011414854594463 0.8610377280236687 1.0429082645312595 1.259058833614256 1.2459788821860638 0.9424911213315583 0.903756165628417 1.029421659684113 0.9245579514916489 1.0 15.115808466427886 ARFEELCSDLFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ARFEELCSDLFR 12 1 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;P17066;P48741 A0A0G2JIW1;P17066 HSPA1B;HSPA1A;HSPA6;HSPA7 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7 0 ;;; 119.69 0.00068343 10993300.0 42877.3 34609.2 46284.399999999994 54586.9 61769.799999999996 64777.6 57629.5 51665.799999999996 53125.3 43573.1 False True 50135.58002472279 38044.97265176545 47387.99563056446 51528.57296611759 49666.451108219495 61380.54862155248 52170.4165585514 50309.627494440094 53902.15700930665 51472.55810553021 0.9740254199516115 0.7391311808083209 0.920645823225038 1.0010882470708475 0.964911264102946 1.1924907344940712 1.0135578739177957 0.9774067842381984 1.0472018293474985 1.0 15.651515863559863 -5.728524838975984 2.408079846460944 1.0353409510980514 0.8516506967518502 0.4396023176545374 0.07970266487938184 0.2475299209811902 2.9212366529465177 0.023284132858677684 0.04431402272379617 1.8684228118949354e-06 5.728524838975984 -0.18369025434620112 ARFEELCSDLFR ddPTM_PC-9_Lapatinib_30min_R1 1 ARFEELCSDLFR 12 1 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;P17066;P48741 A0A0G2JIW1;P17066 HSPA1B;HSPA1A;HSPA6;HSPA7 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7 0 71.806 0.034387 2244200.0 16800.0 14045.0 16088.0 15587.0 19023.0 17378.0 14171.0 16960.0 17239.0 14957.0 False True 16560.428919257323 14012.479665422232 14765.306741475899 16733.31997670773 17904.104540656987 16634.783450096584 14904.705040764466 17748.023515524015 15297.362285282205 17542.29752105026 0.9440285059231995 0.7987824655583258 0.8416974300976227 0.9538841737593506 1.0206248365798476 0.9482670915902159 0.8496438407158038 1.0117274259102544 0.8720272967053377 1.0 14.098550089997856 -5.764976229187554 24.972134782021758 0.9499494764638211 0.8552307570391237 0.30071654930840475 0.062227469389239426 102.30687695737264 722351.0753145919 0.017048967577454475 0.026462720240279798 1.7180024182755502e-06 5.764976229187554 -0.09471871942469745 ARFEELNADLFR ddPTM_PC-9_AZD4547_30min_R2 2 ARFEELNADLFR 12 1 P11142;E9PKE3;P11142-2;E9PN89;E9PNE6;A8K7Q2;P54652 P11142 HSPA8;HSPA2 Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2 0 ; 166.45 0.0001013 71721000.0 76769.0 65789.0 96006.0 152262.0 119750.0 92411.0 86093.0 117218.0 77943.0 91645.0 False True 101179.94510560327 87054.00767598547 94732.89771079403 117160.34832444986 103124.77953546218 86632.52556139417 93755.11021575962 99104.65150167419 82062.90785621184 88436.53644456722 1.1440966502461767 0.98436699554094 1.0711963801315696 1.3247957578922935 1.1660879505395565 0.9796010681139258 1.0601400053079433 1.1206301771417049 0.9279299162473371 1.0 16.432354903662265 -6.7554866563706435 24.999891972121468 1.02785460254517 1.1362216929402893 0.2922317213887866 0.09302753599980204 232.61960907789614 976940.6480652592 0.033639387149077285 0.032797102777889144 1.7559548448055688e-07 6.7554866563706435 0.10836709039511927 ARFEELNADLFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ARFEELNADLFR 12 1 P11142;E9PKE3;P11142-2;E9PN89;E9PNE6;A8K7Q2;P54652 P11142 HSPA8;HSPA2 Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2 0 ; 173.19 0.0011178 34795000.0 64334.0 36298.0 63254.0 85839.0 81485.0 78388.0 89508.0 78664.0 81979.0 57208.0 False True 75224.47554558044 39901.4255548751 64762.21525213084 81029.71912379301 65518.59919496694 74277.1952858127 81029.15425819816 76599.15335139759 83177.78778596931 67579.35754172114 1.11312800656827 0.5904380717179999 0.9583135680470017 1.1990306222394624 0.9695060973984259 1.0991107046253963 1.1990222636871561 1.1334696886413569 1.2308164920718319 1.0 16.044295014813244 -5.543073785547644 7.0338371073485675 1.1182036307796408 0.8325252383955559 0.3735941365368183 0.1413709523077716 0.13558588756089815 28.56699860949613 0.036208397749529685 0.06481007933882826 2.863691394559107e-06 5.543073785547644 -0.2856783923840849 ARFEELNADLFR ddPTM_PC-9_Lapatinib_30min_R1 2 ARFEELNADLFR 12 1 P11142;E9PKE3;P11142-2;E9PN89;E9PNE6;A8K7Q2;P54652 P11142 HSPA8;HSPA2 Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2 0 ; 201.38 4.0543e-06 26519000.0 123229.0 95910.0 124190.0 99001.0 122123.0 120135.0 98792.0 93444.0 117440.0 95350.0 False True 121471.73186256934 95687.92628769281 113979.57758726347 106281.8637976548 114939.96524305595 114997.10609836309 103906.9663670316 97785.74937409337 104212.67050197472 111831.12045411108 1.0862068748780374 0.8556466741917114 1.0192116212770486 0.9503782432481899 1.027799460260443 1.0283104169161137 0.929141780437306 0.8744055230513308 0.9318754035441993 1.0 16.770962192825472 -7.37258084833708 7.433702371668048 0.9225540501888454 0.9887930810252036 0.16578909755825677 0.06412267060103244 0.45182250329073254 27.031478142012176 0.02594281482127815 0.017409630696149137 4.2405203496078415e-08 7.37258084833708 0.06623903083635818 ARGDS(ph)EALDEES ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ARGDSEALDEES 12 1 Q7Z4V5-2;Q7Z4V5;Q7Z4V5-4;Q7Z4V5-3;A0A087WZ99 Q7Z4V5-2 HDGFRP2 Hepatoma-derived growth factor-related protein 2 1 ARGDS(0.992)EALDEES(0.008) 88.163 0.039501999999999995 6902000.0 31218.0 36094.0 34939.0 35786.0 39267.0 33517.0 38596.0 38243.0 31016.0 26993.0 True False 36502.5908163946 39677.1737830641 35772.07826689537 33781.026439777386 31572.913230518072 31759.309516693676 34939.90746915815 37239.16177180788 31469.55032349286 31886.617223529556 1.144762097544134 1.2443205720105608 1.1218524064853979 1.0594107930285537 0.9901618917173818 0.9960074878453417 1.095754598997586 1.167861786992212 0.9869203152810785 1.0 14.960663433122697 -5.57570880974235 3.1572855933315553 1.0473001537961992 1.1942573157095557 0.5239068360190426 0.0583538819228403 0.20310662542220884 4.103931074955615 0.017137550283629805 0.034317394695814844 2.656386046210625e-06 5.57570880974235 0.1469571619133565 ARGGS(ph)PAPLPAK ddPTM_PC-9_AZD4547_30min_R2 1 ARGGSPAPLPAK 12 1 A0A087WWH3;Q9NZM4-2;Q9NZM4 A0A087WWH3 GLTSCR1 Glioma tumor suppressor candidate region gene 1 protein 1 ARGGS(1)PAPLPAK 56.527 0.035949 2960000.0 22237.0 24352.0 19282.0 29998.0 23267.0 26770.0 21137.0 21046.0 18527.0 20854.0 True False 29307.90344166655 32223.307770685013 19026.30808136502 23082.424564479934 20036.778667654267 25096.0676681187 23018.15205220529 17793.82428896784 19506.29939637986 20123.90780746358 1.4563723766810737 1.6012450503641242 0.9454579231529037 1.1470150223963507 0.9956703667775203 1.2470772529981 1.1438211838591452 0.8842131686952196 0.9693097177251697 1.0 14.296622864962318 -5.259062783580631 24.99644522698353 1.0505532420529344 1.5288087509755306 0.7626661820927618 0.10862867118654403 96.55410161836392 1015516.1309065586 0.029159697118732952 0.06998513183985405 5.507280749012435e-06 5.259062783580631 0.47825550892259616 ARGGS(ph)PAPLPAK ddPTM_PC-9_Lapatinib_30min_R1 1 ARGGSPAPLPAK 12 1 A0A087WWH3;Q9NZM4-2;Q9NZM4 A0A087WWH3 GLTSCR1 Glioma tumor suppressor candidate region gene 1 protein 1 ARGGS(1)PAPLPAK 61.409 0.026395 4018100.0 27910.0 31785.0 29586.0 25536.0 24392.0 26122.0 18274.0 19141.0 25464.0 21086.0 True False 27511.998281932865 31711.403785364564 27153.553285262675 27414.00262559879 22957.310516517104 25004.82295335614 19220.138304631284 20030.360737655952 22595.976172192488 24730.687004671112 1.1124639714511944 1.2822694241925 1.09797003537079 1.1085014589534394 0.9282924696827446 1.0110848497105336 0.777177694295391 0.8099395190223642 0.9136817011158881 1.0 14.594014697096359 -6.233556653125652 1.1222790225413073 0.8705994869376834 1.1948542299218814 0.690018519966838 0.08106776191274027 0.2572672066654115 0.6710857812785505 0.033567506548683054 0.051651077608617875 5.840410147657476e-07 6.233556653125652 0.324254742984198 ARGPEEEEIGSPEPMAAPAS(ph)ASQKLSPLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ARGPEEEEIGSPEPMAAPASASQKLSPLQK 30 2 H3BRB3;Q14807-2;Q14807 H3BRB3 KIF22 Kinesin-like protein;Kinesin-like protein KIF22 1 ARGPEEEEIGSPEPMAAPAS(0.333)AS(0.333)QKLS(0.333)PLQK 123.2 3.7469999999999996e-17 6682500.0 33131.0 25099.0 26544.0 39132.0 41407.0 43814.0 41867.0 50543.0 43231.0 32145.0 True False 38739.42393292232 27590.662846487692 27176.90962868059 36939.56090765572 33293.59559263657 41516.31670986112 37901.05466916893 49216.29980473515 43863.17158998322 37972.63404032 1.0201932236722933 0.7265933360638466 0.7156972465966853 0.9727942725393413 0.8767786705890578 1.0933220135789996 0.9981149748243678 1.2960991790160363 1.1551258609926438 1.0 15.212672457123864 -6.779522859403515 1.1937992745844388 1.1508190951719257 0.8274789273276898 0.5112980054104095 0.11909928549559609 0.34369907728415355 1.0335348367777721 0.060512957174467884 0.053627489979555375 1.6614112258861026e-07 6.779522859403515 -0.3233401678442359 ARGPEEEEIGSPEPMAAPAS(ph)ASQKLSPLQK ddPTM_PC-9_Lapatinib_30min_R1 2 ARGPEEEEIGSPEPMAAPASASQKLSPLQK 30 2 H3BRB3;Q14807-2;Q14807 H3BRB3 KIF22 Kinesin-like protein;Kinesin-like protein KIF22 1 ARGPEEEEIGSPEPMAAPAS(0.503)AS(0.381)QKLS(0.116)PLQK;ARGPEEEEIGSPEPMAAPAS(0.333)AS(0.333)QKLS(0.333)PLQK 74.748 6.6444e-06 8679200.0 51966.0 39650.0 48174.0 46208.0 42587.0 43675.0 34101.3 30784.8 44074.0 34112.0 True False 51224.955310602745 39558.192861088726 44213.31967701766 49606.290465369246 40082.11638926343 41807.122061397626 35866.898455057606 32215.174193437684 39109.92200020465 40008.21374861714 1.2803609686866688 0.9887517875615237 1.105106065340042 1.2399026554161983 1.0018471867079755 1.0449634748525274 0.8964883731230646 0.805214009199578 0.9775473168070759 1.0 15.28800859749717 -6.841181929570035 1.6417272541660157 0.9065601489417751 1.1340063616918323 0.5112498333162347 0.09558669897338029 0.29793849386456933 1.6584197975578518 0.04203931284450594 0.0359237180485481 1.4415113639281203e-07 6.841181929570035 0.22744621275005728 ARGS(ph)PPTSSNIVQGQIK ddPTM_PC-9_AZD4547_30min_R2 3 ARGSPPTSSNIVQGQIK 17 1 A2RRE0;Q9Y4E6-2;Q9Y4E6 A2RRE0 WDR7 WD repeat-containing protein 7 1 ARGS(0.903)PPT(0.08)S(0.009)S(0.009)NIVQGQIK;ARGS(0.952)PPT(0.014)S(0.014)S(0.02)NIVQGQIK;ARGS(0.929)PPT(0.067)S(0.003)SNIVQGQIK 124.68 0.00029259 25161000.0 73837.8 67294.5 135230.8 178707.7 152753.0 134878.8 94166.0 184364.0 94926.3 110126.6 True False 97316.68447835074 89046.1311093282 133437.55123376483 137509.40077144172 131545.88265870942 126444.80731395788 102546.59157628618 155874.78006325493 99943.91042211765 106271.10125392838 0.9157398702947322 0.8379148240551102 1.2556334662884865 1.293949146559339 1.2378330619195193 1.1898324739462862 0.9649527516540672 1.466765453863149 0.9404617929319063 1.0 16.697389806528008 -5.257944378173583 24.979577935726944 1.18577204993131 0.8768273191430234 0.3537076707536899 0.15644326703001946 280.15310247705116 2002295.2641558594 0.037855098670649096 0.09220993625174784 5.52148150568327e-06 5.257944378173583 -0.30894473078828666 ARGS(ph)PPTSSNIVQGQIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ARGSPPTSSNIVQGQIK 17 1 A2RRE0;Q9Y4E6-2;Q9Y4E6 A2RRE0 WDR7 WD repeat-containing protein 7 1 ARGS(0.939)PPT(0.035)S(0.013)S(0.013)NIVQGQIK;ARGS(0.991)PPT(0.009)SSNIVQGQIK 112.44 0.00012272 11288200.0 125458.0 117491.0 118407.0 150271.0 153279.0 147990.0 145033.0 133009.0 137185.0 116080.0 True False 146695.5614915508 129154.7300090314 121230.27194104812 141851.80305515512 123245.08027250823 140229.1438784944 131294.42429201002 129517.654684685 139191.07109647797 137124.38511122536 1.0697992291638134 0.9418801032673396 0.884089812637737 1.0344753993981102 0.8987831024550502 1.0226419156939204 0.9574841424850401 0.9445267855139672 1.0150716153335986 1.0 17.065125625792902 ARGS(ph)PPTSSNIVQGQIK ddPTM_PC-9_Lapatinib_30min_R1 2 ARGSPPTSSNIVQGQIK 17 1 A2RRE0;Q9Y4E6-2;Q9Y4E6 A2RRE0 WDR7 WD repeat-containing protein 7 1 ARGS(0.896)PPT(0.035)S(0.035)S(0.035)NIVQGQIK;ARGS(0.995)PPT(0.003)S(0.001)S(0.001)NIVQGQIK 110.38 0.00018687 20681700.0 169019.0 115303.0 140518.0 127545.0 122387.0 135914.0 112570.0 98675.0 154356.0 105684.0 True False 166608.75806571174 115036.02298769502 128965.15245516606 136925.084777647 115188.43728209972 130101.27505100869 118398.3237907597 103259.80073079765 136970.80183926094 123951.33858492173 1.3441465011010307 0.9280740676219592 1.040449856592789 1.1046680603923988 0.9293036977021563 1.0496157325632551 0.9552000417457571 0.8330672496937348 1.1050368911136792 1.0 16.9194143260099 -4.7550439726403395 24.99844332979745 0.9921422260512806 1.3441470875321524 0.6263611822633095 0.08113498697709115 140.10617565497114 547597.5131948562 0.019907695872059254 0.18336059491465073 1.7577456318916733e-05 4.7550439726403395 0.35200486148087184 ARHDS(ph)PDLAPNVTYSLPR ddPTM_PC-9_AZD4547_30min_R2 2 ARHDSPDLAPNVTYSLPR 18 1 Q9BRD0;H7C462 Q9BRD0 BUD13 BUD13 homolog 1 ARHDS(1)PDLAPNVTYSLPR;ARHDS(1)PDLAPNVTYSLPR 103.28 0.00019438 76120000.0 19337.0 22746.6 35103.0 54930.0 42052.0 33909.0 30939.0 34876.0 33832.0 33630.0 True False 25485.763765413783 30098.99361599308 34637.51128410725 42266.73716004013 36213.805670357055 31788.664869564323 33692.51106321518 29486.715570751778 35620.29045060309 32452.62393617534 0.785322130362608 0.927474883854965 1.0673254450003467 1.3024135503855168 1.1158976156004778 0.9795406661748884 1.0382060670803792 0.9086080567396763 1.0976089489915395 1.0 14.98604751067571 -4.988828651198254 2.7551709750385913 1.0661718005176026 0.7836555746510004 0.44612368337541664 0.09861454860399707 0.3111761799579353 4.2556185094322965 0.02862091928403228 0.16217970852259017 1.026056672132317e-05 4.988828651198254 -0.2825162258666022 ARHDS(ph)PDLAPNVTYSLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ARHDSPDLAPNVTYSLPR 18 1 Q9BRD0;H7C462 Q9BRD0 BUD13 BUD13 homolog 1 ARHDS(1)PDLAPNVTYSLPR;ARHDS(1)PDLAPNVTYSLPR;ARHDS(1)PDLAPNVTYSLPR;ARHDS(1)PDLAPNVTYSLPR 130.17 1.958e-05 34294800.0 32664.8 23809.4 36069.5 44096.6 50397.0 41897.3 51368.8 37614.0 43731.299999999996 32169.100000000002 True False 38194.305480792034 26173.03988115718 36929.53367434048 41626.01046510612 40522.069627891586 39700.13183201868 46502.775386094174 36626.6723553273 44370.78753100862 38001.10317954452 1.0050841234880652 0.6887442124376476 0.9718016211229137 1.0953895277312062 1.0663392964261118 1.0447099823509522 1.2237217210874547 0.9638318177837252 1.1676184062701844 1.0 15.213753680436103 -5.524391095242107 5.0927651910332665 1.0805184748912449 0.841354321858491 0.4649407588873643 0.10015949653369835 0.12947667501053367 10.0520738781365 0.02508647536757114 0.048136563891984195 2.9895712252432973e-06 5.524391095242107 -0.23916415303275385 ARHDS(ph)PDLAPNVTYSLPR ddPTM_PC-9_Lapatinib_30min_R1 2 ARHDSPDLAPNVTYSLPR 18 1 Q9BRD0;H7C462 Q9BRD0 BUD13 BUD13 homolog 1 ARHDS(0.995)PDLAPNVT(0.001)Y(0.001)S(0.004)LPR;ARHDS(1)PDLAPNVTYSLPR 69.27199999999999 0.0052671 31090100.0 21987.6 21467.0 24210.0 21232.4 21198.3 24033.0 15397.9 16904.7 24916.0 19923.3 True False 21674.052791967977 21417.294480428554 22219.547253302557 22793.901525210058 19951.457671461336 23005.164613659304 16195.127919496674 17690.15407564142 22109.697702888297 23367.015858871462 0.9275490256381737 0.91656095967844 0.9508936608551468 0.9754733622332089 0.8538299366920067 0.9845144434617749 0.6930764294982953 0.7570566212854785 0.9461926091214675 1.0 14.512185882583363 -7.2224323867128 24.99999171186249 0.8288359173770578 0.9328737299245987 0.16998083239969108 0.08831832350072764 766.2821099546035 491118.7957547434 0.03288630223085651 0.02547324648743154 5.991942171098458e-08 7.2224323867128 0.10403781254754096 ARLS(ph)ASTASELSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ARLSASTASELSPK 14 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;H0YF21 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 ARLS(0.793)AS(0.175)T(0.032)AS(0.001)ELSPK;ARLS(0.79)AS(0.149)T(0.06)AS(0.001)ELSPK 93.81200000000001 0.0017018 3892100.0 57508.0 56554.0 51738.0 62352.0 79592.0 87295.0 82418.0 98730.0 78366.0 67500.0 True False 67242.96856522588 62168.30736763478 52971.63013745766 58858.61958791143 63996.51895595272 82717.09652593522 74610.77038535275 96138.44211308217 79511.95449609362 79737.21567029385 0.8433072060513054 0.7796648885345469 0.6643275626338715 0.7381574474745454 0.8025928472417763 1.037371267990632 0.9357082481267155 1.2056909851305306 0.9971749556050256 1.0 16.282965608551713 -6.718801202035336 3.3056784439369156 1.045954498922425 0.752171080494291 0.7538651880804149 0.0771703990449734 0.11782061671417503 2.642811175392647 0.027896099658584833 0.02666295814762294 1.9107276925451412e-07 6.718801202035336 -0.29378341842813394 ARLS(ph)ASTASELSPK ddPTM_PC-9_Lapatinib_30min_R1 2 ARLSASTASELSPK 14 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;H0YF21 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 ARLS(0.962)AS(0.029)T(0.008)AS(0.001)ELSPK;ARLS(0.969)AS(0.026)T(0.005)ASELSPK 90.444 0.0023257 8671200.0 75773.0 61090.0 67448.0 59772.0 64259.0 95966.0 98792.0 84325.0 103881.0 104103.0 True False 74692.46312493378 60948.54985835841 61902.68579680923 64167.83227354683 60479.41195805484 91861.75788767225 103906.9663670316 88243.04734354716 92180.82786457463 122097.06484147177 0.6117465904844878 0.4991811223102923 0.5069956913147942 0.5255477054821995 0.4953387866987632 0.7523666355693612 0.8510193631758649 0.7227286541090898 0.754979884113187 1.0 16.897668993439027 -6.840200436565777 4.555305932063405 0.8076205949080117 0.524705178167272 0.7803191656051213 0.07686278512180574 0.09986696881306209 3.8238922801772413 0.02656515899319442 0.02363240342836392 1.4447728220506053e-07 6.840200436565777 -0.2829154167407397 ARLS(ph)PVTPSESLPRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ARLSPVTPSESLPRPR 16 2 K7EQZ1;A0A669KB29 K7EQZ1 CXXC1 1 ARLS(0.999)PVT(0.001)PSESLPRPR 58.723 0.016745 2296600.0 3904.3 4307.0 5064.1 4303.6 4594.2 4655.3 4673.7 4916.7 3549.6 3757.7 True False 4565.220876559978 4734.570496028624 5184.847349706196 4062.483244459453 3693.9994897406496 4411.167872812721 4230.973301342224 4787.641834674262 3601.5061848165547 4438.941264063168 1.0284481377393178 1.066599041162994 1.168036935221861 0.9151919349211831 0.8321803038140138 0.993743239750592 0.953149196993298 1.0785548962844154 0.8113435097629406 1.0 12.115999903754151 -5.775630536026659 24.999500756797058 0.9420881860875435 1.0855851481523533 0.41096539902818796 0.08067731451232006 226.68941475013904 399341.2047158697 0.0226910905038259 0.03383531239926808 1.6763683934511822e-06 5.775630536026659 0.14349696206480977 ARLSAS(ph)TASELSPK ddPTM_PC-9_AZD4547_30min_R2 2 ARLSASTASELSPK 14 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;H0YF21 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 ARLS(0.08)AS(0.456)T(0.456)AS(0.009)ELSPK;ARLS(0.079)AS(0.662)T(0.249)AS(0.01)ELSPK 108.25 0.00033160000000000004 9122300.0 73539.0 57401.0 85520.0 109795.0 101026.0 88919.0 66758.0 87300.0 67882.0 85461.0 True False 96922.87229377683 75954.75071226544 84385.94892222458 84483.45906584013 87000.28373569608 83358.88087341962 72699.33267261756 73809.79095442798 71470.10393615045 82469.03640230378 1.175263790169243 0.9210093148383582 1.0232440271348586 1.0244264120379618 1.0549448317946604 1.0107900432687846 0.8815348868388948 0.895000040916764 0.8666295503624185 1.0 16.331564930255468 -7.186630407357644 4.913336925397569 0.902132651678366 1.0311910991774553 0.44997350614428056 0.0671214285665717 0.19616129252682027 8.769620377527579 0.02509660720424924 0.01910258979164044 6.506831982319969e-08 7.186630407357644 0.12905844749908935 ARPATDS(ph)FDDYPPR ddPTM_PC-9_AZD4547_30min_R2 2 ARPATDSFDDYPPR 14 1 E7EX17;P23588-2;P23588;F8VP89;F8W0K0;F8VSC7 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 ARPAT(0.057)DS(0.943)FDDYPPR;ARPAT(0.006)DS(0.994)FDDYPPR 91.065 0.006220600000000001 3690700.0 14977.5 14525.5 24539.4 32337.0 29830.0 25649.0 21084.8 27150.0 24041.0 25315.0 True False 19740.033448646886 19220.583813365847 24213.991522240885 24882.20425166971 25688.61940328048 24045.163975329717 22961.306353330085 22954.591344933808 25311.758179325767 24428.729555286318 0.8080663140492785 0.7868024315331846 0.9912096111032117 1.0185631715049734 1.051574104381598 0.9842985866666325 0.9399304331960773 0.9396555515907494 1.0361471365934527 1.0 14.576291216058939 -5.2637777312123974 24.52540419087022 0.9935056363512286 0.7974343555671713 0.8396108563356057 0.0345637877469301 57.398825963599016 602028.1957419437 0.009919703250947898 0.022390467681022787 5.447813967015431e-06 5.2637777312123974 -0.19607128078405722 ARPATDS(ph)FDDYPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ARPATDSFDDYPPR 14 1 E7EX17;P23588-2;P23588;F8VP89;F8W0K0;F8VSC7 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 ARPAT(0.01)DS(0.986)FDDY(0.004)PPR 70.334 0.035004 0.0 10654.0 11663.0 12681.0 15877.0 16306.0 14601.0 9228.9 16575.0 10293.0 6954.4 True False 12457.51177390826 12820.825561918238 12983.363132960301 14987.463163928496 13110.956353600408 13835.297856408519 8354.671780550158 16139.923812664176 10443.51565255713 8215.177668999886 1.5164019910265476 1.560626693479539 1.5804117276675884 1.8243626331398706 1.5959431289081947 1.6841142594658973 1.016980048048949 1.9646469574928922 1.2712464749199417 1.0 13.004076061226762 ARPATDS(ph)FDDYPPR ddPTM_PC-9_Lapatinib_30min_R1 4 ARPATDSFDDYPPR 14 1 E7EX17;P23588-2;P23588;F8VP89;F8W0K0;F8VSC7 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 ARPAT(0.023)DS(0.966)FDDY(0.011)PPR;ARPAT(0.128)DS(0.872)FDDYPPR;ARPAT(0.001)DS(0.997)FDDY(0.002)PPR;ARPAT(0.042)DS(0.958)FDDYPPR 101.78 0.00076622 13750800.0 43839.9 32856.6 59568.0 41258.700000000004 39413.299999999996 40458.3 30695.899999999998 36133.8 55980.0 54097.0 True False 43214.73498674699 32780.522561403464 54670.548979129555 44293.002432988476 37095.08718352917 38727.9928219037 32285.183505807778 37812.708260922256 49674.942904466494 63447.59437027851 0.6811091171486648 0.5166550897122621 0.8616646465754659 0.6981037322628131 0.5846571103554093 0.6103933995651301 0.5088480316116051 0.5959675640379409 0.782928705138367 1.0 15.953277844547861 -8.56458419861312 3.26964908143845 0.9993838778452517 0.632603853206599 0.585600273508248 0.09615960329938347 0.18872370316183 5.441019857065084 0.09718117823554953 0.02574193165815211 2.725309319802859e-09 8.56458419861312 -0.3667800246386528 ARPFPDGLAEDIDKGEVSAR ddPTM_PC-9_AZD4547_30min_R2 2 ARPFPDGLAEDIDKGEVSAR 20 2 P13639 P13639 EEF2 Elongation factor 2 0 ; 93.738 0.0024562 20128700.0 50975.0 58612.0 87851.0 98416.0 82256.0 72721.0 59875.0 90972.0 66166.0 78985.0 False True 67183.98965413294 77557.18277986973 86686.03833917642 75727.71171204282 70836.17424191226 68173.74437404792 65203.75900675552 76914.36772859357 69663.39967943371 76219.75919116303 0.8814510878423543 1.0175469406214257 1.13731713743366 0.9935443579940192 0.9293675943563602 0.8944366276868535 0.8554705459409965 1.0091132344788498 0.9139808419587677 1.0 16.217877429653562 -6.1850684913709 4.492679714971283 0.9282289677172401 1.0196724429280823 0.19804877254189457 0.07177418105753056 0.3302440828493372 12.488910345922868 0.02230773915503278 0.028983970953418526 6.530275573722508e-07 6.1850684913709 0.09144347521084228 ARPFPDGLAEDIDKGEVSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ARPFPDGLAEDIDKGEVSAR 20 2 P13639 P13639 EEF2 Elongation factor 2 0 ; 130.47 0.00014491 20977200.0 75346.0 68589.0 67640.0 86965.0 98322.0 80951.0 87842.0 86619.0 86423.0 73383.0 False True 88100.58964866652 75398.06263109074 69252.79412612847 82092.63299433418 79056.50991038281 76705.78705390905 79520.96983899361 84345.3430304168 87686.77287874736 86686.75700049182 1.0163096728623344 0.86977602162073 0.7988855105715347 0.947003162130848 0.911979091684492 0.8848616525529251 0.9173370026813028 0.9729899462029507 1.0115359705779496 1.0 16.403523991577764 -7.832518872104249 2.440964101036505 1.0046571635550978 0.9004290099758013 0.3834535848227263 0.052309671447980086 0.31135187483284327 3.650841018192654 0.036926130040584475 0.01504610982617106 1.4705545116199207e-08 7.832518872104249 -0.10422815357929649 ARPFPDGLAEDIDKGEVSAR ddPTM_PC-9_Lapatinib_30min_R1 2 ARPFPDGLAEDIDKGEVSAR 20 2 P13639 P13639 EEF2 Elongation factor 2 0 ; 106.19 0.00053595 31268000.0 101092.0 94644.0 95831.0 94139.0 102433.0 87859.0 95747.0 86869.0 91979.0 79164.0 False True 99650.40954199772 94424.85763291003 87952.14509835746 101062.2960984978 96408.0923310264 84101.4753793322 100704.31116633091 90905.2508708758 81619.35643819087 92847.39192060048 1.0732709608818622 1.016989876394789 0.9472764207913428 1.0884774898677 1.0383500315600775 0.9058033148766585 1.0846218626415416 0.9790824382941685 0.8790699959347119 1.0 16.502573765035272 -8.001416718794436 24.97563538430903 0.9360487268240256 1.0187489780693821 0.22640998839280535 0.06145131000916369 69.06875296026907 1217610.5656641172 0.03327237028806314 0.015636291004276555 9.967431993411223e-09 8.001416718794436 0.08270025124535652 ARPQPSGPAPS(ph)S ddPTM_PC-9_AZD4547_30min_R2 1 ARPQPSGPAPSS 12 1 Q96MG7 Q96MG7 NDNL2 Melanoma-associated antigen G1 1 ARPQPSGPAPS(0.584)S(0.416) 98.337 0.017809000000000002 3203700.0 8612.5 8778.8 11525.0 19590.0 13354.0 13659.0 10773.0 14004.0 10152.0 11273.0 True False 11351.095848871397 11616.375421209332 11372.17096969877 15073.828162482901 11500.027606818896 12804.900570744607 11731.776129933658 11840.003579906188 10688.61399428123 10878.335701234151 1.0434588672956298 1.067844911229523 1.04539621519573 1.3856741119666651 1.0571495422332124 1.177101067885953 1.0784532167547176 1.0884021145406402 0.9825596752882523 1.0 13.409170232163492 -8.034668356468302 1.6806525474460097 0.9885196640189327 1.1295841682934864 0.2186342335655923 0.09701187818402804 0.6043383250589774 3.0546731590330656 0.08737914758900091 0.028497313789854543 9.232762063125695e-09 8.034668356468302 0.14106450427455375 ARPQPSGPAPSS(ph) ddPTM_PC-9_Lapatinib_30min_R1 1 ARPQPSGPAPSS 12 1 Q96MG7 Q96MG7 NDNL2 Melanoma-associated antigen G1 1 ARPQPSGPAPS(0.311)S(0.689) 98.0 0.018318 2966500.0 11116.0 9988.9 12402.0 8631.3 10781.0 10240.0 10032.0 10395.0 13991.0 10763.0 True False 10957.483801575268 9965.771315766191 11382.35543310443 9266.074595172731 10146.882776261516 9802.05907060588 10551.407873047014 10877.989648813207 12415.186248238491 12623.370209203978 0.8680315652618604 0.7894699395332576 0.9016891087298782 0.7340412616922722 0.8038172538790949 0.776500958789831 0.8358629825618002 0.8617341857629925 0.9835080523255433 1.0 13.623809514512574 -8.175453596234368 2.068006809406358 1.0045041711753653 0.8122822780460979 0.7121142034097809 0.04424679492260625 0.1701689511060214 1.2981967473773235 0.03943536060786352 0.01189935798955608 6.676462342314184e-09 8.175453596234368 -0.1922218931292674 ARPSAWEPAAGNS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 2 ARPSAWEPAAGNSPAR 16 1 Q8IY33-4;Q8IY33-2;Q8IY33;Q8IY33-5 Q8IY33-4 MICALL2 MICAL-like protein 2 1 ARPSAWEPAAGNS(1)PAR;ARPSAWEPAAGNS(1)PAR 62.167 0.018181 12545200.0 36034.0 28294.0 47970.0 65160.0 53419.0 38247.0 38474.0 48797.0 43956.0 49618.0 True False 47492.062446238815 37439.48218067352 47333.8864569588 50138.36871196454 46002.693929059344 35855.40904380034 41898.11146598599 41256.54489350773 46279.42442204746 47880.88892254379 0.991879297042 0.7819295552603215 0.9885757662839161 1.047147825368753 0.9607735980732778 0.7488459352081602 0.8750487388353201 0.8616495186680397 0.9665531585454272 1.0 15.547162316129969 ARPSLTVT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 ARPSLTVTPR 10 1 Q8TF76-2;Q8TF76 Q8TF76-2 GSG2 Serine/threonine-protein kinase haspin 1 ARPS(0.001)LT(0.002)VT(0.997)PR;ARPS(0.005)LT(0.013)VT(0.982)PR 83.087 0.01011 17247900.0 51648.0 54084.0 88836.0 112741.0 94586.0 90143.0 58558.0 100171.0 77686.0 91700.0 True False 68070.98965486336 71565.59532973591 87657.97659558867 86750.3042810866 81454.36657320427 84506.34395992623 63769.54855812262 84691.87365058446 81792.32336088773 88489.61091130761 0.7692540282846348 0.8087457340214266 0.9906018988313501 0.9803445103633205 0.9204963806976765 0.9549860496575833 0.7206444677673891 0.957082676467754 0.9243155497979022 1.0 16.433220465631543 -1.522878745280807 0.01819709128777467 1.6225761414783015 1.2781711002913316e-06 0.15687218177440732 0.08685669975389346 9134.071406955209 12.866690727176573 437.3418066025339 748.411968882371 0.02999999999996757 1.522878745280807 -1.6225748633072012 ARPSLTVT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ARPSLTVTPR 10 1 Q8TF76-2;Q8TF76 Q8TF76-2 GSG2 Serine/threonine-protein kinase haspin 1 ARPS(0.009)LT(0.002)VT(0.988)PR 73.877 0.019326 2298300.0 14988.0 14912.0 24277.0 22015.0 26478.0 21142.0 19558.0 20533.0 17298.0 16661.0 True False 17525.172373506382 16392.36481002527 24855.85575103522 20781.570923592997 21289.825973913397 20033.276301636113 17705.32465234209 19994.03050651182 17550.950525399112 19681.507411596576 0.890438522162197 0.83288157086823 1.26290406680892 1.0558932549723428 1.0817172449590513 1.0178730664619862 0.8995919002581023 1.0158790222913059 0.8917482872809775 1.0 14.264553100833872 -7.090407296546036 7.978898384775492 0.9534438244624567 1.031090213235384 0.08656263443813017 0.11347307419894591 0.845204850275616 67.17025127978033 0.04590024319178702 0.035567262330687965 8.120685726377647e-08 7.090407296546036 0.0776463887729274 ARPSQFPEQSSSAQQNGS(ph)VSDISPVQAAK ddPTM_PC-9_AZD4547_30min_R2 1 ARPSQFPEQSSSAQQNGSVSDISPVQAAK 29 1 O00139-1;O00139-5;O00139;O00139-4 O00139-1 KIF2A Kinesin-like protein KIF2A 1 ARPS(0.001)QFPEQS(0.008)S(0.02)S(0.199)AQQNGS(0.488)VS(0.146)DIS(0.138)PVQAAK 57.648 0.0008755000000000001 3646400.0 3532.4 3146.5 4659.3 5048.3 4842.9 5237.4 2439.6 6262.9 3701.7 5332.9 True False 4655.62972151562 4163.544591838879 4597.514637667461 3884.4924304575006 4170.546929538956 4909.904550056216 2656.7196738685725 5295.112712124711 3897.364304829674 5146.196794208427 0.9046738606566902 0.8090527351236484 0.8933810387588642 0.7548278050363603 0.8104134171923866 0.9540841025710218 0.5162491408914769 1.028937081862838 0.757329045250621 1.0 12.329290912468345 -10.833293473529729 3.917448278621821 1.0003470030464032 0.8251114706806421 0.1357617857897725 0.1321263912988005 88851397.5553335 153.9390654166806 278758.4958941794 0.0296414475281184 1.467933989286574e-11 10.833293473529729 -0.17523553236576117 ARPSQFPEQSSSAQQNGS(ph)VSDISPVQAAK ddPTM_PC-9_Lapatinib_30min_R1 1 ARPSQFPEQSSSAQQNGSVSDISPVQAAK 29 1 O00139-1;O00139-5;O00139;O00139-4 O00139-1 KIF2A Kinesin-like protein KIF2A 1 ARPSQFPEQS(0.003)S(0.002)S(0.002)AQQNGS(0.6)VS(0.218)DIS(0.174)PVQAAK 65.275 0.00010217 8641200.0 35335.0 31844.0 34064.0 34155.0 40622.0 38058.0 31715.0 30142.0 41320.0 31622.0 True False 34831.11642035461 31770.267174489527 31263.38941084257 36666.87263773992 38232.69382592483 36430.348057531104 33357.04751731321 31542.507358780917 36666.10648111031 37087.82056633358 0.9391524195404597 0.85662265103086 0.8429556909370368 0.9886499685836009 1.030869251471479 0.9822725493500878 0.8994070562235469 0.8504815564011217 0.9886293106797955 1.0 15.178657871156199 -5.762884171980629 24.999987486049477 0.9576649804664035 0.8772814907857378 0.3239719093664586 0.054763906363922164 51.37748054088731 889038.1362405972 0.016790905312495094 0.0265024530067063 1.7262982410219964e-06 5.762884171980629 -0.08038348968066567 ARPSQFPEQSSSAQQNGSVS(ph)DISPVQAAK ddPTM_PC-9_AZD4547_30min_R2 1 ARPSQFPEQSSSAQQNGSVSDISPVQAAK 29 1 O00139-1;O00139-5;O00139;O00139-4 O00139-1 KIF2A Kinesin-like protein KIF2A 1 ARPSQFPEQSSSAQQNGS(0.229)VS(0.627)DIS(0.144)PVQAAK 104.77 1.4621e-11 12021000.0 26227.0 26200.0 27496.0 43916.0 39708.0 38479.0 32121.0 43484.0 28132.0 37948.0 True False 34566.64044451087 34668.63763107538 27131.38507443277 33791.8446954364 34195.22960997187 36072.902047125106 34979.70677337779 36764.54696291348 29619.00008738371 36619.45207047224 0.94394204418977 0.9467273722271262 0.7409009021276404 0.9227840064456929 0.9337995976609624 0.985074871620271 0.9552220144108424 1.0039622354851738 0.8088324213694809 1.0 15.16032258408922 -5.989219900939214 24.990495584772198 0.948250751391766 0.8754269502055617 0.15411341462161887 0.07396485720682082 398.7843272074402 924455.4103837135 0.02074621587759798 0.030739807291685992 1.0251327284710349e-06 5.989219900939214 -0.07282380118620424 ARQEEGADAS(ph)EEDPTPAGEEDVKDAR ddPTM_PC-9_AZD4547_30min_R2 1 ARQEEGADASEEDPTPAGEEDVKDAR 26 2 Q86X53;E5RHA3;H0YB25 Q86X53 ERICH1 Glutamate-rich protein 1 1 ARQEEGADAS(0.967)EEDPT(0.033)PAGEEDVKDAR 79.782 0.00057355 0.0 6677.5 6265.1 7722.5 8040.7 6992.1 8939.2 7787.2 7373.3 5368.5 5834.4 True False 8800.806099371695 8290.171054291997 7620.09460420814 6187.040842576632 6021.367607431363 8380.230410864646 8480.245714194682 6233.9259065782835 5652.267949990028 5630.1394318531475 1.5631595284443836 1.4724628323393594 1.353446872220712 1.0989143195233766 1.0694881859168173 1.4884587695026785 1.5062230370737777 1.1072418333565854 1.0039303676942148 1.0 12.458954936124288 -1.522878745280339 0.12043036346116671 0.9146395238754286 2.763357178289522 0.40844211374547756 0.1679707085475804 118.34309855268302 0.9828276421192123 1.3184715303883683 36.7075549025845 0.029999999999999905 1.522878745280339 1.8487176544140933 ARQPLSEASNQQPLS(ph)GGEEK ddPTM_PC-9_AZD4547_30min_R2 2 ARQPLSEASNQQPLSGGEEK 20 1 Q9NQW6;Q9NQW6-2;C9JJT6 Q9NQW6 ANLN Actin-binding protein anillin 1 ARQPLSEASNQQPLS(1)GGEEK;ARQPLSEASNQQPLS(1)GGEEK 100.39 0.00014943 83389000.0 292420.0 257610.0 291210.0 374540.0 393270.0 315320.0 351470.0 329260.0 326540.0 279520.0 True False 385403.47728615144 340877.3946618825 287348.36512676615 288195.5895853164 338671.24883433146 295602.99055327626 382750.1491123896 278380.4326420958 343800.23775537714 269734.0898792671 1.4288274702639845 1.2637534796378875 1.0653023696611104 1.0684433314095103 1.2555745140924555 1.095905195689533 1.4189906410558208 1.0320550612149129 1.2745894963045348 1.0 18.04117834006589 -14.522878743390553 0.025655454015836472 5.17730942943947e-07 1.947594083463161 0.17306063542110606 0.13688694060724357 4312.880053215722 8.321601952529262 463.01770033337294 213.18336722557092 3.0000000130541687e-15 14.522878743390553 1.947593565732218 ARQPLSEASNQQPLS(ph)GGEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ARQPLSEASNQQPLSGGEEK 20 1 Q9NQW6;Q9NQW6-2;C9JJT6 Q9NQW6 ANLN Actin-binding protein anillin 1 ARQPLSEASNQQPLS(1)GGEEK;ARQPLSEASNQQPLS(1)GGEEK;ARQPLSEASNQQPLS(1)GGEEK 130.27 1.6467e-05 62697300.0 218041.0 153053.0 167779.0 273828.0 268931.0 283523.0 281697.0 290757.0 253716.0 213353.0 True False 254951.03479394875 168247.09034796135 171779.487665401 258486.3049223544 216235.90108733627 268654.55476628407 255012.6208503334 283124.93683250603 257426.11651648502 252032.2099985818 1.0115811578027403 0.6675618578629616 0.6815775160895808 1.025608214615937 0.8579693091155017 1.0659532556088598 1.0118255156821756 1.1233680680501084 1.021401655438936 1.0 17.943248597986155 -6.2946676292455725 1.2609837327372906 1.0502189672297595 0.790055303365287 0.4193266143430264 0.11420448419490462 0.40241562639908435 1.307903232239811 0.045921915620762206 0.06396761596558215 5.073788628302069e-07 6.2946676292455725 -0.26016366386447254 ARQPLSEASNQQPLS(ph)GGEEK ddPTM_PC-9_Lapatinib_30min_R1 3 ARQPLSEASNQQPLSGGEEK 20 1 Q9NQW6;Q9NQW6-2;C9JJT6 Q9NQW6 ANLN Actin-binding protein anillin 1 ARQPLSEASNQQPLS(1)GGEEK;ARQPLSEASNQQPLS(1)GGEEK;ARQPLSEASNQQPLS(0.999)GGEEK 107.95 5.0281e-05 114595500.0 364803.8 322576.4 344978.0 318075.0 300928.2 304214.0 311840.5 291743.8 286476.5 250694.0 True False 359601.6309151761 321829.4941648349 316615.2404935903 341467.2965670956 283228.19492360455 291203.4763774702 327986.0752427148 305299.28201110393 254210.4998387172 294026.12387124205 1.2230261249597347 1.094560884344305 1.076826903422501 1.1613501959323476 0.9632756137261937 0.9904000112078206 1.1154997757489884 1.0383406684801877 0.8645847399261685 1.0 18.165584816930895 -1.5228787815840708 0.26900945246519836 0.9727453511049715 2.580186112603419 0.49267631644642385 0.07027399579088849 47.97229236039331 0.6692143504362656 0.08457935713299458 35.7566068181738 0.029999997492227058 1.5228787815840708 1.6074407614984474 ARQS(ph)FPGPR ddPTM_PC-9_AZD4547_30min_R2 1 ARQSFPGPR 9 1 Q86WR7;Q86WR7-2;D3DRR9 Q86WR7 PROSER2;C10orf47 Proline and serine-rich protein 2 1 ARQS(1)FPGPR 65.241 0.024378 4173800.0 8873.2 8416.7 13005.0 26566.0 23766.0 13774.0 12739.0 18052.0 11453.0 14915.0 True False 11694.693025974526 11137.233677460767 12832.545202683956 20441.6191406085 20466.50113102124 12912.709602565072 13872.746321286988 15262.478193692257 12058.382198237085 14392.830389772678 0.8125360133670854 0.7738042744792374 0.8915928872338107 1.420264019447766 1.4219927961886092 0.8971626325660478 0.9638650595886092 1.0604222922363857 0.8378047869448655 1.0 13.81306270948434 -5.537296971814003 24.994862547182155 1.094609043898747 0.8030521503074577 0.29889342479534986 0.18609776264404093 287.76494995535165 498856.00128338125 0.05545767001790864 0.09610513403216513 2.9020375542190575e-06 5.537296971814003 -0.29155689359128933 ARQS(ph)FPGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ARQSFPGPR 9 1 Q86WR7;Q86WR7-2;D3DRR9 Q86WR7 PROSER2;C10orf47 Proline and serine-rich protein 2 1 ARQS(1)FPGPR 58.273999999999994 0.037307 2648100.0 9094.8 7363.0 11264.0 9325.6 10976.0 10047.0 9341.3 8092.8 9012.5 5805.6 True False 10634.370009511998 8093.949979628226 11532.576478957877 8803.116866003124 8825.331591875272 9520.117633267339 8456.424438844622 7880.372575030387 9144.290762525126 6858.109322895687 1.5506270764756296 1.1802013643332725 1.6815970606441861 1.2836069609759735 1.2868461519579522 1.3881548375854231 1.2330547736550344 1.149059048785048 1.333354475991956 1.0 12.743595186652517 -12.091344441235167 0.06366630433431189 1.2562435198776284e-05 1.9304645086774888 0.4447000232997068 0.1391369649314554 195.11911821634095 1.487635029439597 39.739108812472374 11.987005779039432 8.103181353647691e-13 12.091344441235167 1.93045194624229 ARS(ph)DPTHQHR ddPTM_PC-9_AZD4547_30min_R2 1 ARSDPTHQHR 10 1 A0A2R8Y6L5;A0A2R8Y6I6;Q13627-5;Q13627-2;Q13627 A0A2R8Y6L5 DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1 ARS(0.975)DPT(0.025)HQHR 81.494 0.006829899999999999 2048700.0 882.82 438.81 837.43 829.47 0.0 542.85 730.31 453.87 496.12 1311.3 True False 1163.5383962032677 580.6467511027553 826.325131032958 638.2485066837511 0.0 508.9055036846555 795.3061752020647 383.7348203950312 522.3438903509459 1265.3917861286568 0.9195084154631668 0.45886717257679344 0.6530191993430109 0.5043880588449292 0.0 0.4021722831326434 0.6285058777212602 0.3032537626698452 0.4127922245718113 1.0 10.305368420881228 -10.316691330100475 12.960494180234614 1.0000332849637066 0.46463910927415164 0.3215376735171608 0.22789991070398283 0.0 0.0 0.2267290792376538 0.054989878946816645 4.822904583374536e-11 10.316691330100475 -0.5353941756895549 ARS(ph)DPTHQHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ARSDPTHQHR 10 1 A0A2R8Y6L5;A0A2R8Y6I6;Q13627-5;Q13627-2;Q13627 A0A2R8Y6L5 DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1 ARS(0.806)DPT(0.194)HQHR;ARS(0.5)DPT(0.5)HQHR 73.46600000000001 0.011748999999999999 3273900.0 925.3199999999999 1172.8400000000001 2262.7 0.0 3477.7799999999997 3687.77 673.53 1760.69 2216.38 3894.11 True False 1081.9584000969398 1289.2718041704702 2316.651349337535 0.0 2796.3339744526206 3494.376849251943 609.7283624650765 1714.4737531052588 2248.7903645209926 4600.081317242203 0.2352041899871425 0.28027152462239563 0.5036109558877084 0.0 0.6078879440611828 0.7596337125942066 0.13254730088784933 0.37270509690317905 0.48885882866722147 1.0 12.167443649080681 -14.522878745279934 0.22007848077870987 4.1566498192824755 0.2989760788789125 0.4564666204075657 0.2098836256839223 148.05401264155194 1.4774277194868795 207.2072281812751 0.41234655053361186 3.0000000000027865e-15 14.522878745279934 -3.857673740403563 ARS(ph)DPTHQHR ddPTM_PC-9_Lapatinib_30min_R1 1 ARSDPTHQHR 10 1 A0A2R8Y6L5;A0A2R8Y6I6;Q13627-5;Q13627-2;Q13627 A0A2R8Y6L5 DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1 ARS(0.702)DPT(0.298)HQHR 89.01299999999999 0.0040541 3437100.0 909.01 2654.1 989.59 1553.7 2357.3 962.94 2428.2 3558.1 1191.6 2195.2 True False 896.0473507079821 2647.9545945174186 908.2297301278682 1667.9642809912607 2218.648248630116 921.7573009227766 2553.92031472615 3723.4223154826623 1057.389459895718 2574.637395079863 0.34802856216581424 1.0284767088280722 0.3527602496038848 0.6478443466170202 0.8617323172847396 0.35801441503345544 0.991953398799651 1.4461928979195786 0.410694516407006 1.0 11.330153546023443 -7.314631022404993 14.796292239997578 0.9994473803850638 0.621888626087064 0.23740932153475058 0.31413999329594455 5.820349037640305 1617.3887124599974 0.12432326489871816 0.08382032554619528 4.845838963391306e-08 7.314631022404993 -0.3775587542979998 ARS(ph)PDLGPQEQMNPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ARSPDLGPQEQMNPK 15 1 H3BUW4;H3BMU4;A0A0C4DGM2;C9K0J8;Q8IWY8-4;Q8IWY8-3;Q8IWY8-2;Q8IWY8 H3BUW4 ZSCAN29 Zinc finger and SCAN domain-containing protein 29 1 ARS(1)PDLGPQEQMNPK 71.929 0.031488999999999996 11107000.0 50613.0 47821.0 55600.0 65046.0 67853.0 72374.0 67848.0 71067.0 60643.0 54658.0 True False 59180.781247683364 52568.35284202108 56925.71486417421 61401.68350197729 54557.69173683612 68578.58003285465 61420.94626301807 69201.56655171076 61529.78914971548 64567.06272751007 0.9165784960273285 0.8141667070077713 0.8816525401568234 0.9509753256255205 0.8449771358979713 1.0621294687397231 0.951273662892651 1.0717781424216168 0.9529593967962786 1.0 15.97851077732015 -6.756825014220997 24.999999663719894 1.0085921169685528 0.8817691693480129 0.6111069100699923 0.05023735375150718 76.81605249040027 416178.60176132683 0.01613319888229767 0.015625566604553182 1.7505518782912195e-07 6.756825014220997 -0.12682294762053992 ARS(ph)PPQPLGELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ARSPPQPLGELK 12 1 A0A044PY82;Q96FF7 A0A044PY82 LOC113230 Uncharacterized protein LOC113230 1 ARS(1)PPQPLGELK 67.51899999999999 0.03466 0.0 13360.0 22592.0 18548.0 13817.0 19639.0 14046.0 18604.0 14303.0 14075.0 12281.0 True False 15621.584127972073 24834.78445467349 18990.254663681706 13042.878285318398 15790.878929741104 13309.40303343017 16841.69443870398 13927.561405281183 14280.820247716081 14507.448083657499 1.0767975206866078 1.7118644375953092 1.309000353072023 0.8990470419129796 1.0884670300856962 0.9174186222608706 1.1608998592713207 0.9600283471612384 0.9843785182180517 1.0 13.824506145622596 -5.628680521452549 5.297357195456976 1.0079139988827523 1.4206798696059555 0.521354412456368 0.1604646680148051 0.1386489861271107 5.925919071084828 0.04078351534772701 0.07196605169012092 2.351361909016275e-06 5.628680521452549 0.41276587072320314 ARS(ph)PPQPLGELKR ddPTM_PC-9_Lapatinib_30min_R1 1 ARSPPQPLGELKR 13 2 A0A044PY82;Q96FF7 A0A044PY82 LOC113230 Uncharacterized protein LOC113230 1 ARS(1)PPQPLGELKR 73.082 0.007066299999999999 8860700.0 39904.0 30068.0 26522.0 28159.0 29353.0 32278.0 26789.0 29366.0 33112.0 24848.0 True False 39334.96164250265 29998.379393372412 24341.463537880634 30229.906795670293 27626.514250218373 30897.545183693055 28176.00334041631 30730.451565853644 29382.57787518212 29142.943692121204 1.3497250675173509 1.0293530986536021 0.8352438173382378 1.0372976427855827 0.9479658109378705 1.0602067351228561 0.9668207727427924 1.0544731476169178 1.0082227171555667 1.0 14.830858989125295 -4.771117932560956 4.726196368589941 0.9892305303514138 1.373364157599628 0.7519766167183174 0.061763085267170156 0.08460681626394034 4.498375918591034 0.015180300891765322 0.10775550016652323 1.6938777658935822e-05 4.771117932560956 0.3841336272482142 ARS(ph)PQELDQGTGAALCFFNPLFPGDLGPTK ddPTM_PC-9_AZD4547_30min_R2 2 ARSPQELDQGTGAALCFFNPLFPGDLGPTK 30 1 E9PNR2;Q13671-2;Q13671 E9PNR2 RIN1 Ras and Rab interactor 1 1 ARS(0.711)PQELDQGT(0.289)GAALCFFNPLFPGDLGPTK;ARS(0.979)PQELDQGT(0.021)GAALCFFNPLFPGDLGPTK 73.23899999999999 5.5313000000000004e-05 1656700.0 9157.9 9539.9 10712.800000000001 10789.5 9832.7 11168.5 10195.25 11559.4 13105.9 9935.54 True False 12069.92170384666 12623.486112087632 10570.741272380825 8302.147471113285 8467.59932975649 10470.131929450261 11102.607499183703 9773.16033858666 13798.651117774865 9587.699768743016 1.2588965022868122 1.3166334383187115 1.1025315276186094 0.8659165046218097 0.8831731837663315 1.0920379425713844 1.158005336731492 1.0193435938042477 1.439203505595787 1.0 13.226969017499023 -5.334152905016888 5.059011400465673 1.0586736404111246 1.2875045366605182 0.2473868286391011 0.15203952781971478 0.28028716935805065 13.303637500974581 0.04172028272243998 0.09128699645204247 4.632837795426356e-06 5.334152905016888 0.22883089624939368 ARS(ph)PQELDQGTGAALCFFNPLFPGDLGPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ARSPQELDQGTGAALCFFNPLFPGDLGPTK 30 1 E9PNR2;Q13671-2;Q13671 E9PNR2 RIN1 Ras and Rab interactor 1 1 ARS(0.788)PQELDQGT(0.212)GAALCFFNPLFPGDLGPTK 82.6 1.8064e-07 1564200.0 2533.0 2476.5 2981.5 2831.7 3969.4 2518.9 3320.7 3105.6 2063.2 2303.3 True False 2961.786870969554 2722.3505533816783 3052.590267401717 2673.049029495265 3191.6245645763192 2386.804449729979 3006.1392562139463 3024.0812906551955 2093.370396809081 2720.870057087231 1.088544035116558 1.000544126056513 1.1219169616169036 0.9824243618443287 1.1730161667452228 0.8772210357907062 1.1048448448993937 1.1114390717697709 0.7693753662937117 1.0 11.409852342876906 -8.248954104138825 24.978272271817865 0.8846876689854257 1.0546606452426213 0.3423809305254134 0.09573251314075722 701.5216202132569 1403484.1741445777 0.0606911698514621 0.02257758656926108 5.636972237081595e-09 8.248954104138825 0.16997297625719554 ARS(ph)PSVAAMASPQLCR ddPTM_PC-9_AZD4547_30min_R2 1 ARSPSVAAMASPQLCR 16 1 P25325-2 P25325-2 MPST 3-mercaptopyruvate sulfurtransferase 1 ARS(1)PSVAAMASPQLCR 93.23700000000001 0.0013354 8824800.0 5314.1 7132.0 8226.3 20414.0 14655.0 6550.3 12688.0 14583.0 7053.6 14785.0 True False 7003.873259853403 9437.279526138525 8117.213887031066 15707.867693155997 12620.406213713562 6140.708705509075 13817.207420087094 12329.532434002558 7426.438895790199 14267.381650203755 0.4909010939476326 0.661458406140257 0.5689350776507155 1.1009635880127782 0.8845635816809686 0.43040193751467903 0.9684473128178895 0.8641762543603422 0.5205186962727769 1.0 13.800432975269452 ARS(ph)PSVAAMASPQLCR ddPTM_PC-9_Lapatinib_30min_R1 2 ARSPSVAAMASPQLCR 16 1 P25325-2 P25325-2 MPST 3-mercaptopyruvate sulfurtransferase 1 ARS(0.639)PS(0.361)VAAMASPQLCR;ARS(0.996)PS(0.004)VAAMASPQLCR 85.57600000000001 0.0022151999999999996 38226000.0 45224.0 48539.0 47344.0 38836.0 40300.0 48431.0 44116.0 38778.0 38922.0 28537.0 True False 44579.09746693411 48426.61092772725 43451.559073125 41692.12899309817 37929.63323284847 46359.719028175175 46400.11061875415 40579.76744604892 34538.194493169794 33469.58242683768 1.3319287016616088 1.4468842278981118 1.298240250475406 1.2456722184758187 1.13325684046881 1.3851298900879474 1.3863367049822555 1.212437219219978 1.0319278577397262 1.0 15.030562931336112 -8.161410975027499 2.87325865330389 1.0047369636123356 1.3147518427238452 0.6802451284373877 0.08188277746614012 0.173477626570697 2.571277989133536 0.07675123587127722 0.02385879298818165 6.895869354370845e-09 8.161410975027499 0.3100148791115096 ARS(ph)SSVPR ddPTM_PC-9_AZD4547_30min_R2 1 ARSSSVPR 8 1 Q7Z591-4;Q7Z591-5;Q7Z591-8;Q7Z591-7;Q7Z591-2;Q7Z591 Q7Z591-4 AKNA AT-hook-containing transcription factor 1 ARS(0.5)S(0.5)SVPR 66.92 0.022522999999999998 68807000.0 2771.5 0.0 1584.6 2582.4 1857.5 1093.7 1031.1 1073.8 1194.2 1000.8 True False 3652.7793492188184 0.0 1563.5871686407525 1987.0675776822784 1599.6181877838922 1025.3107661046474 1122.865902494624 907.8688834692416 1257.322973992381 965.7622966198118 3.7822757856706795 0.0 1.6190186489090952 2.0575120654813888 1.656327021030526 1.0616595508990738 1.1626731613200039 0.9400541796328161 1.3018969350874825 1.0 9.915524331540222 -6.730631019602937 5.723145375492178 1.0924192228908958 1.7284756914236568 0.14821227783964164 0.8608160536565455 0.4150211467691026 37.355104673974914 0.2807185639116031 0.2727696463010829 1.8593835327387287e-07 6.730631019602937 0.636056468532761 ARS(ph)VDALDDLTPPSTAESGSR ddPTM_PC-9_AZD4547_30min_R2 1 ARSVDALDDLTPPSTAESGSR 21 1 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 1 ARS(1)VDALDDLTPPSTAESGSR 73.058 0.00090062 49994000.0 6569.5 8177.8 7855.2 15985.0 11840.0 11153.0 7929.2 10290.0 7274.5 8377.3 True False 8658.464345911241 10821.113924404886 7751.034915503496 12299.905215788112 10196.220373276603 10455.60114690055 8634.883439104231 8699.916940676565 7659.015218813908 8084.013276851666 1.0710601342905384 1.3385819089870656 0.9588102654034917 1.5215097742365824 1.2612819925065164 1.293367636695978 1.0681431540729858 1.0761878590165754 0.9474273428948061 1.0 12.980855975804813 -7.426861467357455 3.077717318660509 1.012803729365146 1.2460125867993859 0.3544606452975686 0.14481315481709348 0.3018389909463286 5.482958775603019 0.06819882462887203 0.04166818022513066 3.742299422987156e-08 7.426861467357455 0.2332088574342399 ARS(ph)VDALDDLTPPSTAESGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ARSVDALDDLTPPSTAESGSR 21 1 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 1 ARS(1)VDALDDLTPPSTAESGSR;ARS(1)VDALDDLTPPSTAESGSR;ARS(0.999)VDALDDLT(0.001)PPSTAESGSR;ARS(1)VDALDDLTPPSTAESGSR;ARS(0.998)VDALDDLT(0.001)PPSTAESGSR 94.632 0.00017571 80971000.0 105482.1 68085.4 94372.6 94932.7 182283.3 148722.9 149590.2 144645.2 162471.0 140748.7 True False 123338.13616355998 74844.46855126694 96622.80069407875 89613.92859496624 146566.19589661813 140923.6093122975 135419.9333167393 140848.41676425745 164846.83101006597 166265.32514390378 0.7418151442990892 0.4501507965445503 0.5811362087100906 0.5389814654222387 0.8815199186587106 0.8475826766063649 0.8144809099524054 0.8471304322915928 0.9914684909038605 1.0 17.343127798449927 -6.2649628977224125 24.755341023093123 0.8827870789925282 0.5691098383421946 0.7573549829604063 0.08818125460036354 128.42706845207408 902294.5442223843 0.02609963501930635 0.03078327627333129 5.432967439761985e-07 6.2649628977224125 -0.31367724065033353 ARS(ph)VDALDDLTPPSTAESGSR ddPTM_PC-9_Lapatinib_30min_R1 3 ARSVDALDDLTPPSTAESGSR 21 1 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 1 ARS(1)VDALDDLTPPSTAESGSR;ARS(0.998)VDALDDLT(0.002)PPSTAESGSR;ARS(1)VDALDDLTPPSTAESGSR 105.52 3.9248e-05 80153800.0 178009.0 216967.0 104623.8 80889.8 146347.2 131916.9 115083.1 118424.4 193901.9 77679.2 True False 175470.55901714775 216464.62624191263 96022.0350235472 86838.70573246256 137739.34542566555 126275.12170031329 121041.53981206713 123926.82995352735 172062.62614447268 91105.946218972 1.926005560552617 2.375965952009791 1.053960131128647 0.9531617785270219 1.5118590074747784 1.3860250284521782 1.328580019586705 1.3602496334945116 1.8885992987869562 1.0 16.475257597140633 -5.259678509307894 24.999866278824914 1.320970714450144 2.150985796034292 0.59305535891114 0.27844317683927966 102.6595555084321 1457473.7374939246 0.07253579123281076 0.17255850988288912 5.499478274134745e-06 5.259678509307894 0.8300150815841483 ARSDEGQLS(ph)PATR ddPTM_PC-9_AZD4547_30min_R2 2 ARSDEGQLSPATR 13 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 ARS(0.01)DEGQLS(0.99)PATR;ARS(0.012)DEGQLS(0.988)PATR 80.488 0.0059919 68059000.0 19245.0 15585.9 30248.0 45492.0 40487.0 30351.0 23521.0 33937.0 16578.800000000003 34188.0 True False 25364.50967913265 20623.73737611365 29846.89175630791 35004.522244393665 34866.078906490664 28453.147172023535 25614.32343378535 28692.816444678378 17455.121521709 32991.088526017316 0.7688291236322736 0.6251305518412777 0.9046955735567851 1.0610296237054597 1.0568332378301097 0.8624494808525313 0.7764012822306688 0.8697141478690753 0.5290859532550314 1.0 15.009788759306772 -10.337602698945206 10.191211185386107 0.9999936732092458 0.8387870830060454 0.09167708247355477 0.15910568858662041 0.0 0.0 0.16531159854076533 0.04009395187783988 4.5961828833583324e-11 10.337602698945206 -0.16120659020320038 ARSDEGQLS(ph)PATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ARSDEGQLSPATR 13 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 ARSDEGQLS(1)PATR;ARSDEGQLS(0.999)PAT(0.001)R 103.77 0.00066755 35025000.0 34476.0 21254.0 38721.0 47545.0 55093.0 66399.0 53066.0 44759.0 50629.0 39287.0 True False 40312.10586796146 23363.956657207415 39644.25549021025 44881.20779296974 44297.92213840963 62916.91955124089 48039.204315430274 43584.12367608056 51369.35334434225 46409.42210427913 0.8686190010593673 0.5034313205777489 0.8542285961055932 0.9670710333803427 0.9545027740029796 1.3556928032818514 1.035117485571984 0.9391223096497453 1.1068733678458322 1.0 15.502130112556769 -5.747022136163928 1.8957468763254346 1.071961666204344 0.6837060785498827 0.5327103081732265 0.13906778921171772 0.25200654508208836 1.8449869410386601 0.04298834310689806 0.08819954082496789 1.7905145884626833e-06 5.747022136163928 -0.38825558765446133 ARSDEGQLS(ph)PATR ddPTM_PC-9_Lapatinib_30min_R1 3 ARSDEGQLSPATR 13 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 ARS(0.002)DEGQLS(0.888)PAT(0.11)R;ARS(0.001)DEGQLS(0.997)PAT(0.003)R;ARS(0.015)DEGQLS(0.963)PAT(0.021)R 70.45100000000001 0.013294 84349000.0 58690.0 36389.6 56225.0 35166.0 46262.0 41213.5 32005.5 34233.100000000006 46879.0 29922.5 True False 57853.06983757215 36305.34211697035 51602.397534776384 37752.224950337084 43540.96011459145 39450.89467836088 33662.58818588577 35823.69480007575 41598.99336224516 35094.56425577497 1.6484909006400377 1.0345004386540044 1.470381485824688 1.0757285565705461 1.2406753307223808 1.1241312013688576 0.9591966419798599 1.0207761674710294 1.1853400731539174 1.0 15.098959970519946 -1.5228787452803376 0.39301767635460827 1.0492699439406221 8.16109542683058 0.48132518081333187 0.15260895839750388 64.28952506523393 0.8619810778638051 0.10742951410872087 352.0354536965294 0.029999999999999995 1.5228787452803376 7.111825482889957 ARSDPT(ph)HQHR ddPTM_PC-9_Lapatinib_30min_R1 1 ARSDPTHQHR 10 1 A0A2R8Y6L5;A0A2R8Y6I6;Q13627-5;Q13627-2;Q13627 A0A2R8Y6L5 DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1 ARS(0.259)DPT(0.741)HQHR 95.50200000000001 0.0036755000000000004 4755600.0 755.0 2008.6 891.24 878.27 2047.7 709.62 2147.9 3156.6 812.86 419.12 True False 744.2335615499575 2003.9492101080157 817.9656874858887 942.8609056228324 1927.2583119330957 679.2712068050141 2259.107752244584 3303.2671597348494 721.3071470047277 491.56433355770434 1.5140104982059128 4.076677401723601 1.6640053633790914 1.9180824182235972 3.9206634419233275 1.3818561690364686 4.595751965758494 6.719908126424476 1.4673707951597224 1.0 8.941236431632328 -7.272773492827241 24.81363462004285 3.9224167088604434 2.500241542310731 0.04988086501503808 1.7496141372303144 1416.9747768918824 3102152.1208242034 0.698381952436151 0.47563895337304035 5.3361312994063895e-08 7.272773492827241 -1.4221751665497124 ARSPS(ph)VAAMASPQLCR ddPTM_PC-9_AZD4547_30min_R2 1 ARSPSVAAMASPQLCR 16 1 P25325-2 P25325-2 MPST 3-mercaptopyruvate sulfurtransferase 1 ARS(0.146)PS(0.852)VAAMAS(0.002)PQLCR 79.837 0.018621000000000002 17412000.0 15429.0 17158.0 24558.0 32697.0 29014.0 23684.0 18945.0 28872.0 20339.0 23657.0 True False 20335.101056863485 22703.987957022568 24232.344874087863 25159.211813614264 24985.90691809521 22203.03573596277 20631.068298671962 24410.495812557205 21414.07801710853 22828.77563063038 0.8907661709889941 0.9945337553083494 1.061482458199565 1.10208327510377 1.0944917643577219 0.9725898618133498 0.9037308278149767 1.0692862467755195 0.9380300706261405 1.0 14.478565865525331 -6.867304941308658 19.154969385166172 0.9764782468772996 1.0328126841779177 0.12403659555367641 0.06857158083115868 4.8477899998164204 855.7262094942404 0.025588508587300024 0.022567012726817014 1.357360037061502e-07 6.867304941308658 0.056334437300618156 ARSPS(ph)VAAMASPQLCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ARSPSVAAMASPQLCR 16 1 P25325-2 P25325-2 MPST 3-mercaptopyruvate sulfurtransferase 1 ARS(0.372)PS(0.628)VAAMASPQLCR 99.344 0.0041811999999999995 28775000.0 17380.0 15878.0 20385.0 22322.0 30770.0 24234.0 23786.0 21273.0 16908.0 17442.0 True False 20322.090729352873 17454.262905953692 20871.055710543016 21071.37070890043 24740.839384293176 22963.12637848118 21532.81788427289 20714.606290606636 17155.247513206625 20604.096529203984 0.9863131198472401 0.8471258558323216 1.0129566070009741 1.0226787027052673 1.2007728341412993 1.114493243900966 1.045074597362352 1.005363484938348 0.8326134314548078 1.0 14.330643583696192 -5.437407492626001 5.7485164002610745 1.0412047884802553 0.9172610688742993 0.18509379088035782 0.09350166981896652 0.3534652374016553 18.50994206283076 0.026267541913551802 0.055351919957306 3.6525191985649284e-06 5.437407492626001 -0.12394371960595607 ARSPS(ph)VAAMASPQLCR ddPTM_PC-9_Lapatinib_30min_R1 1 ARSPSVAAMASPQLCR 16 1 P25325-2 P25325-2 MPST 3-mercaptopyruvate sulfurtransferase 1 ARS(0.483)PS(0.514)VAAMAS(0.002)PQLCR 77.597 0.022756000000000002 34205000.0 23589.0 22844.0 24669.0 16974.0 19475.0 21616.0 15522.0 20022.0 19152.0 14381.0 True False 23252.616534307188 22791.106121531175 22640.810045093778 18222.32458360408 18329.51878932317 20691.534069357116 16325.653210270697 20952.29521390457 16994.90008049916 16866.736688522007 1.3786079052346172 1.3512457413911467 1.3423349438128769 1.0803704901615359 1.0867258514681504 1.2267657017162024 0.9679200850618885 1.242225784443699 1.0075985885322065 1.0 14.041893253074386 -5.7466773220230944 8.178791687308832 1.0981507808435174 1.3576606091582393 0.6753162520654621 0.0855774225255691 0.09087340353160285 34.550718665366986 0.021851865171999902 0.036427934870527215 1.791936756909804e-06 5.7466773220230944 0.2595098283147219 ARSVDALDDLT(ph)PPSTAESGSRS(ph)PTSNGGR ddPTM_PC-9_AZD4547_30min_R2 1 ARSVDALDDLTPPSTAESGSRSPTSNGGR 29 2 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 2 ARS(0.003)VDALDDLT(0.765)PPS(0.16)T(0.056)AES(0.045)GS(0.103)RS(0.789)PT(0.071)S(0.007)NGGR 73.781 7.574800000000001e-05 4249500.0 6378.7 5750.0 9386.3 17602.0 12083.0 10102.0 8651.6 11853.0 7814.9 9065.6 True False 8406.99391479779 7608.575052621497 9261.83152910053 13544.13084818908 10405.484017761923 9470.320343045758 9421.575639629998 10021.39120484347 8227.979659565448 8748.216103353885 0.9609952263953244 0.8697287495795316 1.0587108754149015 1.5482163092652157 1.1894406693694586 1.0825430271909988 1.0769710679664122 1.1455353967537996 0.940532282508546 1.0 13.094773143752501 -10.750880469772069 14.69512108369845 0.99999999994985 1.1055637326139083 0.024388301210581553 0.176598593817773 0.0 0.0 0.18555560209006802 0.045003843931907754 1.7746778556412062e-11 10.750880469772069 0.10556373266405827 ART(ph)PLTAAQQK ddPTM_PC-9_AZD4547_30min_R2 1 ARTPLTAAQQK 11 1 I3L2J0 I3L2J0 CIC 1 ART(0.999)PLT(0.001)AAQQK 68.033 0.02755 9355400.0 25829.0 22590.0 25960.0 36359.0 38164.0 28217.0 25646.0 31979.0 26560.0 25465.0 True False 34042.08472342515 29891.775728472978 25615.75343803732 27976.99429095028 32865.58735859191 26452.586529372616 27928.44431711486 27037.38035431447 27963.907376685333 24573.478100942753 1.385318129716409 1.2164242931213791 1.0424146444721059 1.138503641040417 1.337441416456673 1.0764689646581926 1.1365279348080317 1.1002667283503995 1.1379710784861385 1.0 14.584814449046661 ART(ph)PLTAAQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ARTPLTAAQQK 11 1 I3L2J0 I3L2J0 CIC 1 ART(1)PLTAAQQK 73.877 0.017043 6662300.0 24612.0 23703.0 23163.0 22029.0 27880.0 26593.0 27273.0 22399.0 25762.0 17789.0 True False 28778.32549084195 26056.077192330282 23715.293766166666 20794.78654898161 22417.114138254587 25198.416265699037 24689.504000579087 21811.04998370225 26138.720513084296 21014.004882353493 1.3694831447863869 1.2399386665323786 1.1285470760541023 0.9895679888436701 1.066770197482887 1.1991248887002688 1.1749071221217853 1.0379292336615986 1.2438714399954425 1.0 14.359063518871324 -4.997378195269112 2.287250325966885 1.1063207815483513 1.380511696240331 0.5304165269171561 0.07992759092234479 0.315460774319426 2.705196136441486 0.021717103352206325 0.14586234860547148 1.0060551874671015e-05 4.997378195269112 0.27419091469197965 ARTDEVPAGGS(ph)RSEAEDEDDEDYVPYVPLR ddPTM_PC-9_AZD4547_30min_R2 1 ARTDEVPAGGSRSEAEDEDDEDYVPYVPLR 30 2 D6RD33;D6RGI7;A0A499FJW5;Q9UJV9 D6RD33 DDX41 Probable ATP-dependent RNA helicase DDX41 1 ART(0.006)DEVPAGGS(0.495)RS(0.495)EAEDEDDEDY(0.003)VPYVPLR 52.773 0.0018125999999999997 4760600.0 3215.7 2234.4 4038.4 7310.5 6994.7 5536.9 3237.8 4834.1 1081.3 3791.6 True False 4238.225709284845 2956.6261039265178 3984.848177356313 5625.177171099094 6023.606642310626 5190.67676771036 3525.9579275502824 4087.1009215670147 1138.4553104822983 3658.8572380732217 1.1583468371443546 0.8080736447327189 1.0890963812118453 1.5374136800323344 1.6463081914293811 1.418660644557918 0.9636773719564623 1.1170430152446476 0.3111505140555351 1.0 11.837177410111739 -7.894075472071813 2.1186557012360803 0.6813903040611099 1.2593371297804936 0.360790746371246 0.2916806863621569 0.3782565247292862 3.235809090210501 0.24127523830667028 0.08922934373434899 1.276217007440822e-08 7.894075472071813 0.5779468257193837 ARVDHGAEIIT(ph)QSPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ARVDHGAEIITQSPGR 16 1 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 ARVDHGAEIIT(0.946)QS(0.054)PGR 70.555 0.014091999999999999 11353000.0 14692.0 12699.0 12021.0 24529.0 30646.0 30851.0 24319.0 21433.0 27560.0 15555.0 True False 17179.065419772873 13959.672795232762 12307.626229896376 23154.719654090968 24641.136294151733 29233.119249918418 22015.32826568704 20870.40646014064 27963.012861602478 18374.99836668774 0.9349152079881002 0.7597101516232199 0.6698028475588341 1.2601209095108514 1.3410143392896268 1.590918195830455 1.1981132093921105 1.135804534164033 1.5217967535875794 1.0 14.165456501260541 -5.807228310202918 7.097198960253302 1.3108258853567039 0.7857153127377564 0.6379148536845505 0.1738459660358573 0.11959860784704848 14.624631741689802 0.04863026962350454 0.07335280735793517 1.5587328558175423e-06 5.807228310202918 -0.5251105726189474 ARVDHGAEIITQS(ph)PGR ddPTM_PC-9_AZD4547_30min_R2 2 ARVDHGAEIITQSPGR 16 1 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 ARVDHGAEIITQS(1)PGR;ARVDHGAEIIT(0.003)QS(0.997)PGR 121.82 3.2404000000000003e-05 70359000.0 31760.0 29877.0 41338.0 75127.0 69094.0 52400.0 43908.0 57645.0 32816.0 42940.0 True False 41859.019350961455 39534.15597342134 40789.831110230625 57807.6308505795 59501.49074925454 49123.419716451994 47815.72693893315 48737.28980032079 34550.586764808206 41436.68366991877 1.0101923137577073 0.9540859082340466 0.9843893742838853 1.3950834316537095 1.4359617005848861 1.1855055802188499 1.15394676175896 1.1761870276240747 0.8338164086690757 1.0 15.3386209230079 -8.25027816603376 23.582731234619693 0.9169082124235102 1.1665009880484933 0.28377267630194536 0.15556263490820316 429.1394928213729 906746.2771608463 0.12194159376143072 0.04500912091588514 5.619812603534371e-09 8.25027816603376 0.24959277562498317 ARVDHGAEIITQS(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ARVDHGAEIITQSPGR 16 1 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 ARVDHGAEIITQS(1)PGR;ARVDHGAEIIT(0.29)QS(0.71)PGR 150.13 1.4529000000000001e-05 24742800.0 45628.0 24405.0 46641.0 84450.0 79302.0 108613.0 99137.0 68234.0 66069.0 91911.0 True False 53351.91920592133 26827.767112973914 47753.0983269775 79718.54029059391 63763.34237417023 102917.143077741 89746.0256702751 66442.9297998989 67035.13413473214 108573.7367329242 0.4913888092215099 0.24709260195185478 0.4398218184609715 0.7342341038394034 0.5872814576790232 0.9479009028758253 0.8265905583689861 0.6119613435000305 0.6174157411532123 1.0 16.72831564141468 -5.71813305041068 3.4299067589103447 0.751442584566354 0.36190006847846173 0.5879254293263818 0.1417536046154092 0.1647450742597045 3.9669334873985447 0.04047499847979688 0.07170036732041422 1.9136695636055564e-06 5.71813305041068 -0.3895425160878923 ARVDHGAEIITQS(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 2 ARVDHGAEIITQSPGR 16 1 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 ARVDHGAEIIT(0.011)QS(0.989)PGR;ARVDHGAEIIT(0.28)QS(0.72)PGR 101.62 0.00076125 57558000.0 107138.0 75308.0 105539.0 77754.0 92707.0 92806.0 81530.0 90675.0 89458.0 71334.0 True False 105610.19247329711 75133.62895290964 96861.9908123214 83472.28853974033 87254.15652897464 88836.90372135256 85751.22447064624 94888.09152536179 79382.29800549783 83663.98685341966 1.2623136482645452 0.8980402653359646 1.1577501199174838 0.9977087117063261 1.0429117689770748 1.0618296720307618 1.0249478622251584 1.134156942480005 0.9488227968932033 1.0 16.352319128148288 -4.735880966524318 24.880672482237603 1.0380565580572476 1.2623147819538534 0.46670880955038163 0.07413898980006212 2125.007015538781 2068543.2545678997 0.016750982822547507 1.2795833941869645 1.8370417794103863e-05 4.735880966524318 0.22425822389660577 ARVGGS(ph)DEEASGIPSR ddPTM_PC-9_Lapatinib_30min_R1 1 ARVGGSDEEASGIPSR 16 1 H7C446;A8MV53;A0A0A6YYI3;A0A0B4J1V8;Q9NQ55-2;Q9NQ55;Q9NQ55-3 H7C446 PPAN;PPAN-P2RY11 Suppressor of SWI4 1 homolog 1 ARVGGS(0.995)DEEAS(0.005)GIPSR 52.568999999999996 0.038079 3225700.0 13474.0 7096.8 10704.0 6549.1 7043.5 8823.2 5913.3 6660.2 8439.6 5314.5 True False 13281.85828917102 7080.367795626089 9823.958438634883 7030.7426611571545 6629.2151780538015 8445.852303883772 6219.461740000886 6969.65720625548 7489.043375072086 6233.104243873876 2.1308577186439517 1.1359296297001507 1.5760940382619513 1.1279680855758552 1.063549544285135 1.3549993668379068 0.9978112825745857 1.1181679197978303 1.2014949665622219 1.0 12.605735125577462 -2.6650572247672004 1.2510059102131124 1.1600463973270654 199.99999999495967 0.7203535740233056 0.1751883949663828 162.85403453026962 1.6016066034822822 0.0493910021657885 91547.22652574567 0.0021624335721195896 2.6650572247672004 198.8399535976326 up ARVS(ph)SGYVPPPVATPFSSK ddPTM_PC-9_AZD4547_30min_R2 1 ARVSSGYVPPPVATPFSSK 19 1 Q15942;Q15942-2;H7C3R3 Q15942 ZYX Zyxin 1 ARVS(0.781)S(0.215)GY(0.004)VPPPVATPFSSK 100.44 0.00021096 11607000.0 8262.2 11558.0 17400.0 45102.0 44508.0 35688.0 25438.0 34590.0 31770.0 29603.0 True False 10889.407735564031 15293.897470991193 17169.26463104196 34704.430718953736 38328.83246400295 33456.42371833471 27701.932720064255 29244.910299125608 33449.297340259516 28566.607980451925 0.3811935859873749 0.5353767406146637 0.6010256675483087 1.2148600471817275 1.341735514774148 1.171172431155595 0.9697312589237278 1.0237445873566033 1.1709229658330036 1.0 14.80204211934817 -5.6823390728243695 4.657883629184445 1.1326450582464536 0.4857218034069075 0.8658550007847461 0.11265526194311996 0.07658238059961588 3.019679113963348 0.03480691565282078 0.06121199422647214 2.0780736100156183e-06 5.6823390728243695 -0.646923254839546 down ARVS(ph)SGYVPPPVATPFSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ARVSSGYVPPPVATPFSSK 19 1 Q15942;Q15942-2;H7C3R3 Q15942 ZYX Zyxin 1 ARVS(0.677)S(0.273)GY(0.05)VPPPVATPFSSK 65.064 0.0051183999999999995 6806900.0 10676.0 15139.0 31447.0 29318.0 39881.0 33281.0 33329.0 31436.0 33182.0 30504.0 True False 12483.23593938846 16641.899869834546 32196.815743411626 27675.407510238456 32066.60433815393 31535.68577214791 30171.83583893597 30610.83830919522 33667.22397582344 36034.13373046886 0.3464280849030982 0.46183710129717637 0.8935088042976161 0.7680331020927905 0.8898952470457154 0.8751614790584723 0.8373126454105378 0.849495607086346 0.9343147868532202 1.0 15.137076542564913 -5.188196091723144 3.618207235819791 0.8717053371918102 0.3681684455040914 0.9101745578831827 0.06019498026316497 0.059686681490544416 1.5055481572229794 0.015114441324666585 0.04635789214140571 6.4834162961291466e-06 5.188196091723144 -0.5035368916877188 down ARVS(ph)SGYVPPPVATPFSSK ddPTM_PC-9_Lapatinib_30min_R1 1 ARVSSGYVPPPVATPFSSK 19 1 Q15942;Q15942-2;H7C3R3 Q15942 ZYX Zyxin 1 ARVS(0.738)S(0.261)GY(0.001)VPPPVATPFSSK 108.96 8.1885e-05 7374900.0 59773.0 45636.0 55769.0 46952.0 44147.0 39554.0 32641.0 28093.0 55565.0 28781.0 True False 58920.626058974245 45530.3326458675 51183.88809456548 50405.00670728052 41550.36025634146 37862.36762487743 34330.99126636041 29398.303338538666 49306.68457461024 33755.75750172811 1.7454985584594813 1.3488167949878356 1.5163009774538505 1.493226946683097 1.2309118008746895 1.1216565832640277 1.0170410563176622 0.8709122684340185 1.460689619306751 1.0 15.042845973883974 -6.410960812234964 1.99294599660097 1.0774287354590237 1.5238544654382056 0.5981154074880961 0.1674568198023312 0.23131064906955096 1.8179127187409698 0.05828536584870558 0.06820695324603497 3.881853916063363e-07 6.410960812234964 0.44642572997918184 ARVSS(ph)GYVPPPVATPFSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ARVSSGYVPPPVATPFSSK 19 1 Q15942;Q15942-2;H7C3R3 Q15942 ZYX Zyxin 1 ARVS(0.39)S(0.576)GY(0.034)VPPPVATPFSSK 87.46799999999999 0.00055391 6677000.0 10824.0 14092.0 32358.0 37927.0 58569.0 35733.0 40280.0 40288.0 35507.0 24881.0 True False 12656.289416255204 15490.960629216477 33129.537438398365 35802.073150993034 47092.8248910844 33859.098575648626 36464.38679805397 39230.482688664495 36026.222702355575 29391.728342112357 0.4306071854277899 0.5270517081848871 1.1271721435629387 1.2181003013591398 1.6022475556025733 1.1519941318706133 1.2406343163497444 1.3347456887200202 1.2257265814047873 1.0 14.84312257682656 -5.287813350957415 2.613324954090879 1.2752459531744476 0.42506291318698214 0.8178716401303849 0.14438795880675118 0.10688297306804316 1.4085278948715276 0.03875380814673119 0.11915779310597112 5.1545012471857335e-06 5.287813350957415 -0.8501830399874655 down ARVSS(ph)GYVPPPVATPFSSK ddPTM_PC-9_Lapatinib_30min_R1 1 ARVSSGYVPPPVATPFSSK 19 1 Q15942;Q15942-2;H7C3R3 Q15942 ZYX Zyxin 1 ARVS(0.355)S(0.591)GY(0.054)VPPPVATPFSSK 118.05 2.7495e-05 7612200.0 65931.0 48010.0 59787.0 49955.0 43106.0 46867.0 30665.0 30503.0 54621.0 27449.0 True False 64990.81184973541 47898.835794725586 54871.54364449401 53628.85734499486 40570.58982965671 44862.6076623131 32252.683655002653 31920.28073667624 48469.00779537094 32193.52307650653 2.018754259833182 1.4878407585555657 1.70442804641462 1.6658275398299272 1.2602096929013467 1.3935289889118079 1.0018376546846248 0.9915125058173676 1.5055515260068435 1.0 14.974482845364177 -6.34697320601694 1.0858363125023558 1.1329064997826923 1.7578097016104162 0.6399640650792957 0.1962699869018103 0.3278649944794329 0.8117790671829105 0.08657604556362261 0.1194434707630614 4.4980760510905313e-07 6.34697320601694 0.6249032018277239 ARVT(ph)PTLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ARVTPTLPK 9 1 Q9UPP1-4;Q9UPP1-3;Q9UPP1-2;Q9UPP1;H0Y3N9;Q9UPP1-5;H0Y589 Q9UPP1-4 PHF8 Histone lysine demethylase PHF8 1 ARVT(0.99)PT(0.01)LPK;ARVT(0.994)PT(0.006)LPK 72.531 0.023091999999999998 13250500.0 50555.0 48236.0 46312.0 52263.0 63770.0 60647.0 59125.0 53140.0 48372.0 40920.0 True False 59112.96299323557 53024.55129938166 47416.25371923808 49334.87354893212 51274.7262767753 57466.56455705826 53524.251972069054 51745.13130648408 49079.34898916674 48338.47207745823 1.2228968035752588 1.0969430563385287 0.9809216485630249 1.0206130113065477 1.0607436286900416 1.1888370088523494 1.107280591871027 1.0704751119060398 1.0153268582945965 1.0 15.560884251471489 -8.23108659782816 2.8851340151950247 1.001790372192941 1.0915085086396028 0.21323918759280414 0.06729158842829994 0.48794524870784695 7.522152604965122 0.06545817683810659 0.01927156250596063 5.8737221949628424e-09 8.23108659782816 0.08971813644666171 ARVT(ph)PTLPK ddPTM_PC-9_Lapatinib_30min_R1 2 ARVTPTLPK 9 1 Q9UPP1-4;Q9UPP1-3;Q9UPP1-2;Q9UPP1;H0Y3N9;Q9UPP1-5;H0Y589 Q9UPP1-4 PHF8 Histone lysine demethylase PHF8 1 ARVT(0.995)PT(0.005)LPK;ARVT(0.997)PT(0.003)LPK 81.525 0.012329999999999999 21316800.0 77154.0 82085.0 89482.0 77869.0 70211.0 85388.0 61398.0 70690.0 72838.0 55796.0 True False 76053.76981168934 81894.93722578743 82125.13537050883 83595.74602336899 66081.32702013705 81736.15428914997 64576.888017278754 73974.51546653251 64634.21742185656 65440.26425650334 1.162186165899097 1.2514456987029794 1.254963382308582 1.277435948236737 1.0097961518174952 1.2490193188825207 0.9868066510880756 1.1304128476098116 0.987682708133828 1.0 15.997890953635608 -7.0054519401335416 0.6736365380328434 1.0086817141990432 1.2400270198142302 0.4985673709269076 0.08360664203818437 0.6198448090548416 0.5911773545491129 0.06553361342488387 0.054246671241461784 9.875249111150821e-08 7.0054519401335416 0.23134530561518707 AS(ph)ADFGAAGSPRPLGR ddPTM_PC-9_AZD4547_30min_R2 1 ASADFGAAGSPRPLGR 16 1 Q86UD0 Q86UD0 SAPCD2 Suppressor APC domain-containing protein 2 1 AS(1)ADFGAAGSPRPLGR 89.87700000000001 0.0017213 10134000.0 16928.0 18934.0 17357.0 25661.0 23521.0 19233.0 18937.0 26355.0 19562.0 22752.0 True False 22310.751875726557 25054.045225449656 17126.834839137668 19745.252908497885 20255.515152013428 18030.357469590093 20622.356314170007 22282.440327651213 20596.007383385477 21955.45940516984 1.0161824202354452 1.1411305390198392 0.7800718046056837 0.8993322591941976 0.9225730502019863 0.8212243313544373 0.9392814759008902 1.0148929210018889 0.9380813675224553 1.0 14.422292101881181 -10.865339566043122 20.975992277451542 0.9999982411479661 0.9393181439087692 0.03156712678526763 0.09671310768274285 0.0 0.0 0.09818804231179687 0.02381409821318557 1.3635166137238363e-11 10.865339566043122 -0.06068009723919687 AS(ph)ADFGAAGSPRPLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASADFGAAGSPRPLGR 16 1 Q86UD0 Q86UD0 SAPCD2 Suppressor APC domain-containing protein 2 1 AS(1)ADFGAAGSPRPLGR;AS(1)ADFGAAGSPRPLGR 60.618 0.021119 14323500.0 32753.0 30954.0 28635.0 29055.7 28402.0 27559.0 25094.0 29173.0 25051.3 29425.8 True False 38297.43599876263 34026.90855214071 29317.766998842224 27427.803328850387 22836.83198546294 26113.757525153236 22716.914655172928 28407.23966134852 25417.627870096592 34760.464605495385 1.1017527076639844 0.9788968282881149 0.8434227600688424 0.7890516896173546 0.6569771792363385 0.7512488058351451 0.6535273596884417 0.8172284226850506 0.731222328543855 1.0 15.085159744773243 -5.148602405226806 1.4498137053485955 0.7520045903412106 1.1326280314004367 0.5772751404559067 0.09284590220619535 0.41181258549649696 1.2513918957492933 0.02611623704608282 0.1863505313312277 7.102276808790563e-06 5.148602405226806 0.3806234410592261 AS(ph)ADFGAAGSPRPLGR ddPTM_PC-9_Lapatinib_30min_R1 1 ASADFGAAGSPRPLGR 16 1 Q86UD0 Q86UD0 SAPCD2 Suppressor APC domain-containing protein 2 1 AS(1)ADFGAAGSPRPLGR 62.438 0.017667 9434700.0 19551.0 17544.0 15444.0 20912.0 11526.0 10395.0 10254.0 9690.5 16547.0 10576.0 True False 19272.19915478571 17503.37794590014 14174.253935564002 22449.938240386982 10848.06334098787 9950.430081928529 10784.901946792674 10140.756006909513 14683.302612365256 12404.047508365822 1.5537024621832278 1.4111021369512744 1.1427119999342372 1.8098881212157387 0.8745583515115909 0.8021921937349508 0.8694663527787098 0.8175360502344216 1.1837509169859441 1.0 13.598523336245686 -6.28569863318814 24.93350547572172 0.9065852514182761 1.4504305979015255 0.6813998129167709 0.18517306807644884 431.92047873224135 443923.7753071942 0.05613439410092445 0.0636810288328595 5.179661357458081e-07 6.28569863318814 0.5438453464832494 AS(ph)AELIEEEVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASAELIEEEVAK 12 0 P12081-3;P12081-2;P12081-4;P12081;A0A2R8YFR1;D6RF05;A0A2R8YCI2;E7ETE2;B4E1C5;B4DDD8 P12081-3 HARS Histidine--tRNA ligase, cytoplasmic 1 AS(1)AELIEEEVAK 115.37 0.00072576 849800.0 3706.8 5306.7 6575.0 5564.6 4858.6 4059.2 4899.3 4891.9 4562.2 3032.2 True False 4334.288027362787 5833.514105241487 6731.772935826359 5252.833502676611 3906.59220775193 3846.328406186798 4435.202836139664 4763.4928083964915 4628.91354416556 3581.913857118007 1.2100480916786025 1.628602567772277 1.8793787914382496 1.466487948122521 1.0906438188033807 1.0738193489894639 1.2382215243189043 1.329873636947031 1.2923017495149827 1.0 11.806514926451888 -6.102158953584403 4.965608980763853 1.188024881312167 1.5919971929390968 0.5141000872098216 0.17973486879378683 0.18916600106076434 7.265411665277191 0.055766086969217143 0.07344891423510946 7.903892892903732e-07 6.102158953584403 0.4039723116269298 AS(ph)ASPGENDSGTGGEEPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASASPGENDSGTGGEEPQR 19 0 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 AS(0.709)AS(0.291)PGENDSGTGGEEPQR 145.48 4.3746e-14 0.0 2296.3 2452.1 2832.3 2073.5 3938.4 3585.8 3418.3 2479.2 2260.2 2400.0 True False 2685.0182360076533 2695.5282826356606 2899.8327735575667 1957.3285173777012 3166.698792040957 3397.7543355598687 3094.493877651137 2414.1236269295314 2293.251149121696 2835.101001610454 0.9470626388557065 0.9507697542713609 1.0228322630870443 0.6903911064423659 1.1169615439598595 1.1984597140030653 1.0914933457020886 0.8515123889971502 0.8088781132732255 1.0 11.469184417334679 AS(ph)ASPSTSSTSSRPK ddPTM_PC-9_AZD4547_30min_R2 2 ASASPSTSSTSSRPK 15 1 J3KP75;F6TH74;O75167-5;O75167-2;O75167;O75167-4;F5H858 J3KP75 PHACTR2 Phosphatase and actin regulator;Phosphatase and actin regulator 2 1 AS(0.853)AS(0.147)PSTSSTSSRPK;AS(0.538)AS(0.46)PS(0.001)TSSTSSRPK 78.441 0.0056116000000000004 24273000.0 16242.4 15995.0 21437.0 32384.0 31240.0 24848.0 18215.7 28040.0 19443.5 23609.0 True False 21407.145337092457 21165.07095072711 21152.731373313018 24918.36912781247 26902.865241652096 23294.25063195418 19836.86201151326 23707.062295099204 20471.243715308032 22782.45609602033 0.9396329020395604 0.9290074284143689 0.9284658021137592 1.0937525358455642 1.1808588647451195 1.022464414450172 0.8707077905870909 1.0405841317188091 0.8985529755452475 1.0 14.475635666829936 -5.719280765594957 24.928388968585622 1.0181407589641789 0.9320323838182634 0.17208867766877545 0.08316440033112035 268.25478494147274 158616.98118720078 0.02460897027291872 0.04262345784805013 1.908618962906932e-06 5.719280765594957 -0.08610837514591552 AS(ph)ASPSTSSTSSRPK ddPTM_PC-9_Lapatinib_30min_R1 2 ASASPSTSSTSSRPK 15 1 J3KP75;F6TH74;O75167-5;O75167-2;O75167;O75167-4;F5H858 J3KP75 PHACTR2 Phosphatase and actin regulator;Phosphatase and actin regulator 2 1 AS(0.48)AS(0.48)PS(0.038)T(0.001)SSTSSRPK;AS(0.986)AS(0.012)PS(0.001)TSSTSSRPK 55.912 0.032351 22444000.0 21935.8 16162.5 18842.8 14134.2 15252.599999999999 13644.6 13753.0 11732.9 14927.3 8442.3 True False 21622.991469466942 16125.076724271034 17293.617719311413 15173.67621830899 14355.472055765373 13061.052265116119 14465.063046054174 12278.053367057282 13246.030282562391 9901.540306342351 2.183800782552641 1.628542249526798 1.7465583317611832 1.5324561380202246 1.4498221096539992 1.319092975539368 1.4608901846098326 1.24001448130173 1.3377747171394894 1.0 13.273437256265236 -1.5228787452803376 0.22586207963984678 1.10197927928558 6.3180366133385295 0.8568308323532041 0.11511707861437227 17.6530466098602 0.22890535718916877 0.16384243177399246 33.84229593419329 0.029999999999999995 1.5228787452803376 5.21605733405295 up AS(ph)DGQLQAK ddPTM_PC-9_Lapatinib_30min_R1 3 ASDGQLQAK 9 0 Q9BRG2;Q9BRG2-2 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 AS(1)DGQLQAK;AS(1)DGQLQAK;AS(1)DGQLQAK 104.24 0.002716 29590500.0 172927.0 234087.0 226296.0 170265.0 222002.0 222672.0 216494.0 209761.0 214154.0 172603.0 True False 170461.029269072 233544.98593376265 207690.8164078209 182786.85608738934 208944.27883272528 213148.83763378425 227703.00000672252 219507.261830179 190033.72137840526 202437.1985709593 0.8420440041276364 1.1536663596532595 1.0259518402445196 0.9029311676792345 1.032143698429442 1.052913393084079 1.1248080966053624 1.084322759748309 0.9387292588510786 1.0 17.627114889285586 -6.5083950773467185 23.83803106797654 1.049806044629855 0.9930295763681557 0.08103145035232673 0.08913331550804442 1016.0164134783214 1672219.1720043195 0.028167909450231107 0.030759186335275364 3.1017366569301434e-07 6.5083950773467185 -0.05677646826169924 AS(ph)DKDITVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASDKDITVSK 10 1 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 AS(1)DKDITVSK 66.267 0.02201 16828000.0 37665.0 37160.0 35442.0 43610.0 52974.0 42443.0 39774.0 42535.0 37678.0 31778.0 True False 44040.940582340416 40848.99921811555 36287.071694533515 41166.67308552761 42594.12497704086 40217.21436336871 36006.3187811767 41418.50131955779 38228.969470227086 37539.099845490404 1.1732018285896932 1.0881720495762703 0.9666473581915871 1.0966345291967088 1.1346602649599153 1.0713420015104604 0.9591684118526396 1.1033429541474054 1.0183773619393155 1.0 15.196106435578196 -4.8496332068362715 3.886305757447982 1.0493740144155599 1.1769187609340326 0.32605628710465406 0.05612056338346724 0.2799279883332547 7.089456123633952 0.014327686490892248 0.08682608162277825 1.4137310388724656e-05 4.8496332068362715 0.1275447465184727 AS(ph)DKDITVSK ddPTM_PC-9_Lapatinib_30min_R1 2 ASDKDITVSK 10 1 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 AS(1)DKDITVSK;AS(1)DKDITVSK 115.57 0.005370300000000001 42785000.0 38913.0 33776.0 34007.0 33782.0 38604.0 30848.0 28856.0 35587.0 36268.0 31337.0 True False 38358.093484229765 33697.79374719127 31211.075730816192 36266.440973448436 36333.388618384175 29528.70295020021 30350.02248650763 37240.501936730725 32183.11592102878 36753.55869607218 1.043656583065222 0.9168579844430825 0.8491987398801655 0.9867463794009205 0.9885679076368487 0.8034243212850003 0.825770988259461 1.0132488732502136 0.8756462520313214 1.0 15.165596326494637 -4.7622731471007285 7.384634230515421 0.9137713920263744 1.0458655694724337 0.20817555385000885 0.0733453498443634 0.16344635127234483 61.01201494362234 0.018463250335609034 0.10872669574029958 1.728728742890692e-05 4.7622731471007285 0.13209417744605934 AS(ph)DLEDEESAAR ddPTM_PC-9_AZD4547_30min_R2 2 ASDLEDEESAAR 12 0 E7ERS3;Q86VM9;H3BPD0 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 AS(1)DLEDEESAAR;AS(1)DLEDEESAAR 182.37 0.0006032 46442000.0 38861.0 49614.0 54197.0 44478.0 44199.0 55715.0 45895.0 47484.0 54643.0 41209.0 True False 51217.989640985936 65650.75524535008 53478.31236830929 34224.28427824984 38062.73178027471 52231.13224240689 49979.56608960408 40146.438873769315 57531.317424104556 39766.28545304341 1.2879752045602764 1.650914952136312 1.3448153821522313 0.8606356839303574 0.957160854896033 1.3134526307236352 1.2568326540989263 1.0095596914923017 1.4467360169216292 1.0 15.279258186632118 -5.531785818747127 24.74424208303987 1.1259841658421592 1.4765501358779776 0.37350219621902725 0.18693552136813066 164.1384380555061 455982.3650968096 0.05078011183313632 0.08812718406703338 2.9390987715878576e-06 5.531785818747127 0.35056597003581835 AS(ph)DLEDEESAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASDLEDEESAAR 12 0 E7ERS3;Q86VM9;H3BPD0 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 AS(0.999)DLEDEES(0.001)AAR;AS(0.996)DLEDEES(0.004)AAR 142.39 6.162e-05 21877000.0 49241.0 50071.0 51041.0 59747.1 70462.0 71567.0 61841.0 56865.3 62593.5 42175.2 True False 57576.52874591862 55041.71797228911 52258.011014070406 56399.66368971171 56655.476915699284 67813.90053349691 55982.972789931824 55372.646128765744 63508.81152223204 49821.229901300496 1.1556625330201993 1.1047844077982576 1.048910496942716 1.1320407746144279 1.1371753974748904 1.3611446499382134 1.123677052951888 1.11142671986346 1.2747339166063874 1.0 15.604473016355126 -4.434245628442589 18.639114530948504 1.148720686611773 1.4672736268511473 0.0 0.09871328392077482 1304.9378182370947 703184.1457385748 0.02393703351317629 62170.60557090036 3.6792082598159624e-05 4.434245628442589 0.3185529402393743 AS(ph)DLEDEESAAR ddPTM_PC-9_Lapatinib_30min_R1 2 ASDLEDEESAAR 12 0 E7ERS3;Q86VM9;H3BPD0 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 AS(1)DLEDEESAAR;AS(1)DLEDEESAAR 228.7 1.2527e-15 56782000.0 40979.0 36791.0 44555.0 38255.0 44700.0 42243.0 34312.0 45554.0 39302.0 36041.0 True False 40394.63194537175 36705.81269993231 40891.85988727366 41068.40031493899 42070.83388358126 40436.36536324262 36088.5074700946 47670.605143053115 34875.394891592405 42270.63882838622 0.9556191499581818 0.868352447876493 0.9673821125176216 0.9715585440208705 0.9952731978900026 0.9566064408775432 0.8537488069818311 1.1277474498691662 0.8250501023460368 1.0 15.367368295267587 -5.299003820742994 23.855858474089416 0.9641798145002377 0.9119857662546439 0.05836982183979034 0.0803032605829537 802.3318383426479 509531.3282641437 0.01952148354857349 0.040639129539310266 5.023381701397631e-06 5.299003820742994 -0.052194048245593816 AS(ph)DPAS(ph)S(ph)LRVAKTDS(ph)KT(ph)EEK ddPTM_PC-9_Lapatinib_30min_R1 1 ASDPASSLRVAKTDSKTEEK 20 3 H0YDT0;Q96D71-4;Q96D71-2;H0YCR2;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 5 AS(1)DPAS(1)S(1)LRVAKT(0.305)DS(0.865)KT(0.83)EEK 43.07 0.033781 3073600.0 10185.0 6275.3 8473.5 5959.2 8089.1 11902.0 6748.8 6126.0 9523.3 9053.1 True False 10039.760032299751 6260.769928403282 7776.841538655896 6397.459447308443 7613.315041782488 11392.979204917108 7098.219841867987 6410.636324062504 8450.685669205172 10617.916272502509 0.9455489923479596 0.589642051013056 0.7324263385647317 0.6025155297067192 0.7170253415445444 1.0729957660734055 0.6685134502567542 0.6037565337244459 0.7958892735941165 1.0 13.374213049807883 -6.555035195828997 24.999406435281873 0.8047641575105089 0.7032499972474507 0.09726406886912742 0.158658934190273 528.5610138786079 410916.0855285673 0.05284457254372688 0.052844959395571885 2.7858953866432257e-07 6.555035195828997 -0.10151416026305815 AS(ph)DPGLPAEEPK ddPTM_PC-9_AZD4547_30min_R2 4 ASDPGLPAEEPK 12 0 F8VPD4;P27708 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 AS(1)DPGLPAEEPK;AS(1)DPGLPAEEPK;AS(1)DPGLPAEEPK;AS(1)DPGLPAEEPK 190.85 5.9204e-05 82978000.0 314319.0 424503.0 317851.0 216083.0 251751.0 370750.0 454629.0 418266.0 397733.0 311359.0 True False 414265.9037586535 561715.2931413887 313636.0880598458 166268.40279907043 216799.7191885771 347566.9438907365 495090.10026692605 353632.60049650335 418756.3543919874 300458.4161803037 1.3787794964280662 1.8695275715102815 1.0438585546947508 0.5533824111596645 0.7215631432287007 1.1567888438916725 1.647782433792185 1.1769768508807223 1.3937248279332393 1.0 18.19680580839556 -5.2755392926322475 24.679414877466883 1.0835258629921334 1.6241535276352561 0.3226753809179349 0.3114073689847208 751.027717717276 1314542.2596379668 0.09133142544884429 0.19164960991086594 5.302256184927594e-06 5.2755392926322475 0.5406276646431227 AS(ph)DPGLPAEEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ASDPGLPAEEPK 12 0 F8VPD4;P27708 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 AS(1)DPGLPAEEPK;AS(1)DPGLPAEEPK;AS(1)DPGLPAEEPK;AS(1)DPGLPAEEPK 172.33 7.2537e-05 74153000.0 167991.0 352316.0 215971.0 198881.0 205050.0 128630.0 224290.0 144391.0 142909.0 146128.0 True False 196428.5583265088 387291.6041046712 221120.56771457856 187738.34235090186 164871.9244637412 121884.41635982659 203043.62748102067 140600.8892449103 144998.77376773424 172619.84965138813 1.1379256714868144 2.243609902840376 1.2809683716046523 1.0875825852591463 0.9551156764225311 0.7060857520498162 1.1762472733644156 0.8145117118851555 0.8399889935054652 1.0 17.39723884478836 -5.613095130905285 2.973783457806 0.927218857506603 1.7046058808953786 0.5256288122831521 0.2820842367526515 0.171323234680418 3.028426957831318 0.07446778489199904 0.14680839451412414 2.437276881692462e-06 5.613095130905285 0.7773870233887755 AS(ph)DPGLPAEEPK ddPTM_PC-9_Lapatinib_30min_R1 4 ASDPGLPAEEPK 12 0 F8VPD4;P27708 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 AS(1)DPGLPAEEPK;AS(1)DPGLPAEEPK;AS(1)DPGLPAEEPK;AS(1)DPGLPAEEPK 172.33 0.00019054 95014000.0 124857.0 304746.0 236705.0 257687.0 311643.0 307131.0 356159.0 366810.0 282438.0 289186.0 True False 123076.5162840304 304040.37936053885 217244.02860772377 276638.1615986318 293312.7714537118 293995.7230873293 374599.170320629 383853.33170574094 250626.85823600783 339171.4147838762 0.36287408348506056 0.8964210016173584 0.640513967682548 0.8156293530069706 0.8647921336195562 0.8668057220407759 1.1044538365927086 1.1317384513383493 0.7389386231021563 1.0 18.37165505976443 -4.4135269592194595 0.44919825369949123 0.9987401381682582 1.8107869368251019e-12 0.5352000954185518 0.14675569117165366 5.735477908348483 0.7026114532381144 0.10201422821684097 3.2650268270142226 3.8589845585846093e-05 4.4135269592194595 -0.9987401381664475 AS(ph)DPGLPAEEPKEK ddPTM_PC-9_AZD4547_30min_R2 2 ASDPGLPAEEPKEK 14 1 F8VPD4;P27708 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 AS(1)DPGLPAEEPKEK;AS(1)DPGLPAEEPKEK 105.39 0.00046043 62330000.0 198593.0 177396.0 189789.0 213823.0 199260.0 212333.0 242240.0 226404.0 207106.0 218460.0 True False 261741.44300898933 234735.78783214669 187272.27385407026 164529.41088241866 171596.18847796417 199055.7839437668 263798.89071893884 191418.46404634972 218053.20034472118 210811.78189404862 1.2415883052520154 1.1134851464332387 0.8883387454511009 0.7804564308702114 0.8139781701774442 0.9442346255761442 1.251347948149885 0.9080064801243142 1.0343501600603708 1.0 17.685595973314797 -5.033413076700568 3.6219003759427655 0.9492945735499021 1.2275026206654795 0.3635113802105693 0.12420765754482743 0.2600721899209525 6.994754644802477 0.03534281626582264 0.13768743125596722 9.259486936265195e-06 5.033413076700568 0.27820804711557745 AS(ph)DPGLPAEEPKEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASDPGLPAEEPKEK 14 1 F8VPD4;P27708 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 AS(1)DPGLPAEEPKEK;AS(1)DPGLPAEEPKEK;AS(1)DPGLPAEEPKEK 76.34100000000001 0.007746600000000001 38594000.0 121689.0 126432.0 108875.0 149147.0 155583.0 133644.0 183454.0 164879.0 131636.0 117061.0 True False 142288.5442326943 138983.33340002096 111470.99291073655 140790.77713109806 125097.62801191081 126635.47337318405 166075.90902805832 160551.1009537408 133560.92746915462 138283.2326456339 1.0289645498621258 1.0050628029226156 0.8061063570620548 1.0181333950435627 0.9046478421030795 0.9157688242485731 1.2009837046089762 1.1610308631211332 0.9658504860919711 1.0 17.07726670941034 -7.24175297738904 24.87395865377655 1.0953855096110077 0.9440909790658036 0.3537683713671219 0.08896013019910841 776.345227540562 980921.1242063144 0.03397524235049613 0.026277187502918256 5.73121924647285e-08 7.24175297738904 -0.15129453054520403 AS(ph)DPGLPAEEPKEK ddPTM_PC-9_Lapatinib_30min_R1 2 ASDPGLPAEEPKEK 14 1 F8VPD4;P27708 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 AS(1)DPGLPAEEPKEK;AS(1)DPGLPAEEPKEK 114.06 8.4412e-05 68516000.0 281910.0 372260.0 396580.0 430070.0 504670.0 444820.0 416970.0 419540.0 488530.0 346990.0 True False 277889.9117040381 371398.05484158697 363974.7232430693 461698.78247146297 474986.3028193956 425796.085526065 438558.66635012114 439033.36000607006 433506.6069510365 406966.7591648873 0.6828319646407479 0.9126004679195696 0.8943598341789893 1.1344876997297961 1.1671378365006695 1.0462674799283762 1.0776277336509295 1.07879415239462 1.0652137974133564 1.0 18.634551435153284 -4.925897072430173 1.131435100171256 1.0836680999781383 0.576840158919827 0.7956569432354166 0.061266829180240144 0.5640392665548921 0.7164015174211249 0.01972103969804998 0.32156058085169054 1.1860498080575026e-05 4.925897072430173 -0.5068279410583113 AS(ph)DSSSPSCSSGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASDSSSPSCSSGPR 14 0 Q92610;H0YM74 Q92610 ZNF592 Zinc finger protein 592 1 AS(0.493)DS(0.056)S(0.025)S(0.399)PS(0.004)CS(0.017)S(0.008)GPR 129.76 0.00043161 0.0 6681.2 7758.5 8318.1 7051.2 7545.4 8368.2 9180.0 8647.0 8721.3 9913.0 True False 7812.195200284953 8528.712605859777 8516.435050569915 6656.144124298837 6066.933035107108 7929.356860625829 8310.403942555498 8420.025412253824 8848.8325134214 11710.148428735178 0.6671303312530902 0.7283180617020556 0.7272696074177586 0.5684081773007699 0.5180918988370502 0.6771354700482037 0.7096753720185861 0.7190366085874864 0.7556550258327656 1.0 13.515471741984909 -8.844311188939821 0.8184091403325324 1.0007686806171405 0.6498665398713641 0.7303841317174944 0.06287139933915473 0.6653392696810195 0.8359076301055381 0.07106828035405842 0.02447370835273218 1.4311620483434237e-09 8.844311188939821 -0.3509021407457764 AS(ph)EAASPLPDSPGDK ddPTM_PC-9_AZD4547_30min_R2 1 ASEAASPLPDSPGDK 15 0 Q68CZ2;Q68CZ2-2 Q68CZ2 TNS3 Tensin-3 1 AS(0.575)EAAS(0.425)PLPDSPGDK 184.01 5.078e-07 14607000.0 32103.0 35067.0 44419.0 46614.0 50670.0 56734.0 52896.0 69842.0 56906.0 52972.0 True False 42311.086216118245 46401.72197743968 43829.975037141 35867.86247912088 43635.34512786528 53186.41401132035 57603.64152687 59049.52370949788 59913.93498409846 51117.466403421924 0.8277226786280206 0.9077469061403528 0.8574363739241763 0.7016752785838345 0.8536288708734638 1.040474377027417 1.1268876487785764 1.155173130911374 1.1720834227434964 1.0 15.641528711573773 -6.847378948654953 2.9880068292306508 1.1233424976470276 0.8254769857845058 0.8153914841218042 0.06482180476713122 0.10764023742662424 1.9376269587202737 0.025466886876015084 0.02254442318609391 1.421088259046077e-07 6.847378948654953 -0.29786551186252186 AS(ph)EGLDACASPTK ddPTM_PC-9_AZD4547_30min_R2 1 ASEGLDACASPTK 13 0 Q92618 Q92618 ZNF516 Zinc finger protein 516 1 AS(0.695)EGLDACAS(0.127)PT(0.177)K 108.57 0.0008828 19863000.0 52925.0 44460.0 52697.0 71674.0 65379.0 57495.0 59363.0 62218.0 65281.0 54000.0 True False 69754.04909161315 58830.82553731336 51998.20334839189 55150.66665226135 56302.25437368674 53899.82856101924 64646.191998630995 52603.63772740664 68731.62038619713 52109.47643632078 1.3386058326042583 1.1289851589510067 0.9978646285562883 1.0583615577035588 1.080460949218894 1.0343575151227304 1.2405841781509823 1.0094831367513304 1.3189850500645324 1.0 15.66925813908732 -4.777685303704439 4.249009552356555 1.0926884240497832 1.3582406139641408 0.34429405547674485 0.10121221180764903 0.22614886793316763 8.278574584414867 0.023988669774077362 0.18198584378894525 1.6684557627021847e-05 4.777685303704439 0.2655521899143576 AS(ph)ETPPPVAQPKPEAPHPGLETTLQER ddPTM_PC-9_AZD4547_30min_R2 1 ASETPPPVAQPKPEAPHPGLETTLQER 27 1 Q6P1N0;Q6P1N0-2 Q6P1N0 CC2D1A Coiled-coil and C2 domain-containing protein 1A 1 AS(0.534)ET(0.466)PPPVAQPKPEAPHPGLETTLQER 66.47399999999999 0.00014822 28835000.0 33030.0 26297.0 46854.0 49664.0 44907.0 43160.0 42149.0 52238.0 37032.0 36088.0 True False 43532.852933320406 34796.99098413697 46232.68534614025 38214.732101151116 38672.43820124428 40461.19837713871 45900.17934656765 44165.817409821415 38989.43591767359 34824.57010433231 1.2500614595642847 0.9992080556884776 1.3275881140134655 1.0973497156364624 1.1104929101890988 1.1618577991320322 1.318040085177031 1.2682372611493347 1.1195956131221028 1.0 15.087817922981118 -7.026909502989524 24.598663575933042 1.204696705877279 1.1525298375494932 0.0 0.1159760305171688 2266.7071097701905 2072048.9904336885 0.04228789454378537 0.032870269843257346 9.399191477554323e-08 7.026909502989524 -0.05216686832778583 AS(ph)GEMASAQYITAALR ddPTM_PC-9_AZD4547_30min_R2 6 ASGEMASAQYITAALR 16 0 A6NJA2;P54578-2;P54578-3;P54578 A6NJA2 USP14 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 14 1 AS(1)GEMASAQYITAALR;AS(1)GEMASAQYITAALR;AS(1)GEMASAQYITAALR;AS(1)GEMASAQYITAALR;AS(1)GEMASAQYITAALR;AS(0.904)GEMAS(0.095)AQY(0.001)ITAALR 174.19 3.9586e-10 87560300.0 57084.64 78143.5 71723.79000000001 42756.8 56780.4 68663.9 90744.53 110360.0 83976.76000000001 57498.03 True False 75236.36808572641 103401.85819557024 70772.68568110812 32899.880345974925 48897.42156104685 64370.335478406225 98820.61737455212 93306.39782051161 88415.60009164657 55485.04147073827 1.3559757024855899 1.8635988269036865 1.2755273097963216 0.5929504506782369 0.8812721458779912 1.1601385485555396 1.7810316935000974 1.6816496004552792 1.593503361410935 1.0 15.759811259034867 -7.242182986673985 23.84156687336543 1.5708502870863934 1.1818971192644745 0.15428778426741308 0.36391347289642784 801.71317118759 992611.3187948861 0.1534643075868302 0.1186436444603407 5.725547385753789e-08 7.242182986673985 -0.3889531678219189 AS(ph)GEMASAQYITAALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASGEMASAQYITAALR 16 0 A6NJA2;P54578-2;P54578-3;P54578 A6NJA2 USP14 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 14 1 AS(1)GEMASAQYITAALR;AS(0.999)GEMAS(0.001)AQYITAALR;AS(0.912)GEMAS(0.083)AQY(0.005)ITAALR 103.87 0.0011515 107571000.0 173827.0 314260.0 256361.0 164137.0 243360.0 118350.0 204236.0 104971.0 122276.0 136484.0 True False 203252.47786025456 345457.6559280134 262473.6184945061 154940.93602933353 195675.3549743771 112143.51765673212 184889.28753940752 102215.62247596815 124064.0551765349 161227.46879325047 1.2606566324060742 2.142672452242055 1.6279708442925958 0.9610083020531789 1.2136601562932228 0.6955608650070603 1.1467604678238774 0.633983918751736 0.7694970100636389 1.0 17.298738035397903 -5.744859449287155 4.065634786485262 0.9081448442538829 1.7444336946581827 0.6368567952339985 0.2630681570544615 0.12061588989625713 4.445733917311081 0.07182589255223247 0.12212838374364494 1.7994531778940102e-06 5.744859449287155 0.8362888504042998 AS(ph)GEMASAQYITAALR ddPTM_PC-9_Lapatinib_30min_R1 7 ASGEMASAQYITAALR 16 0 A6NJA2;P54578-2;P54578-3;P54578 A6NJA2 USP14 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 14 1 AS(1)GEMASAQYITAALR;AS(1)GEMASAQYITAALR;AS(1)GEMASAQYITAALR;AS(1)GEMASAQYITAALR;AS(0.952)GEMAS(0.047)AQYITAALR;AS(0.999)GEMAS(0.001)AQYITAALR;AS(1)GEMASAQYITAALR 199.41 3.9445e-12 131321200.0 30611.96 126259.2 101769.0 102337.87 142547.1 129903.43 164144.4 166710.2 141131.6 120567.5 True False 30175.427836854087 125966.85457974189 93401.94565970027 109864.13834892646 134162.7598363813 124347.7631185855 172642.99386728255 174456.1644975065 125235.87302636652 141407.43172890463 0.21339350745513913 0.8908078807430417 0.6605165267322247 0.7769332700953757 0.9487673893518394 0.8793580478639581 1.220890527156029 1.2337128421366166 0.885638551631848 1.0 17.109498418040197 -4.855763574460311 0.49584384870661474 1.0909215464775797 1.8918029519347326e-17 0.6357464351389019 0.166705220967146 2.893307789229479 0.5782269858524783 0.10916603112221489 1.8359303871730859 1.3939154299461029e-05 4.855763574460311 -1.0909215464775797 AS(ph)GQAFELILS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 ASGQAFELILSPR 13 0 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 2 AS(1)GQAFELILS(1)PR 96.15299999999999 0.028165 0.0 8535.0 10319.0 13008.0 18706.0 14371.0 12638.0 9652.2 15118.0 10135.0 11158.0 True False 11248.952460971539 13654.41495095675 12835.50542072378 14393.620704819039 12375.834711516722 11847.74386214733 10511.227101210952 12781.860477079532 10670.71540898742 10767.361816230878 1.0447268934545049 1.2681300381653273 1.1920752399511043 1.3367824867853781 1.1493841223818826 1.1003386033046525 0.976211933861661 1.1870930591198272 0.991024133033426 1.0 13.394377188309841 -6.714917272236769 2.954369932242255 1.0542210510980528 1.215094415418555 0.41697206468936343 0.08938897190955031 0.25543493881985535 4.553785510003674 0.031336368096379005 0.029930979089614555 1.9278921179789746e-07 6.714917272236769 0.16087336432050225 AS(ph)GQAFELILSPR ddPTM_PC-9_AZD4547_30min_R2 4 ASGQAFELILSPR 13 0 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 AS(1)GQAFELILSPR;AS(1)GQAFELILSPR;AS(0.908)GQAFELILS(0.092)PR;AS(1)GQAFELILSPR 168.69 0.00013167 124409300.0 40567.1 33756.5 75228.0 87084.7 73707.5 74024.0 33055.2 63115.7 44159.0 48303.9 True False 53466.59395190141 44667.62848066394 74230.42756689797 67008.66786020284 63474.48590906129 69395.26757806556 35997.04876359256 53362.61881950045 46493.154587614736 46612.795163562885 1.1470368546723866 0.9582696837622928 1.5924903732210363 1.4375595289892282 1.3617395328113502 1.488760056859059 0.772256815693631 1.1448062411244089 0.9974333104134104 1.0 15.50843840707339 -7.255077256348325 24.999722183973667 0.9906912764616124 1.3321648728150766 0.459395444180027 0.18706718732792407 521.354813507182 2048648.3933758829 0.07731846591751 0.05842309700493385 5.5580537663748565e-08 7.255077256348325 0.3414735963534642 AS(ph)GQAFELILSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ASGQAFELILSPR 13 0 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 AS(1)GQAFELILSPR;AS(0.996)GQAFELILS(0.004)PR;AS(0.982)GQAFELILS(0.018)PR;AS(1)GQAFELILSPR 186.75 3.8334e-05 75999400.0 28559.9 38799.4 38196.7 46292.8 76176.5 67903.0 64840.9 57215.9 66476.7 47856.0 True False 33394.52698626268 42651.1480156984 39107.45418979143 43699.1644992826 61250.261662580815 64342.04714360033 58698.70054453669 55714.043250257135 67448.79597593928 56531.91397211243 0.5907199073913617 0.7544614186729729 0.6917765814382899 0.7729999115338583 1.0834634343495955 1.1381544091243876 1.0383285549732695 0.9855325839089978 1.1931100724665402 1.0 15.78677792195815 -6.175719730873418 3.4421804772167817 1.075401064011941 0.69136196424607 0.8743666939425995 0.06935636770548723 0.0817264275452152 1.8554416527730961 0.02110676367902229 0.027737610111504652 6.672372275182863e-07 6.175719730873418 -0.3840390997658709 AS(ph)GQAFELILSPR ddPTM_PC-9_Lapatinib_30min_R1 4 ASGQAFELILSPR 13 0 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 AS(0.999)GQAFELILS(0.001)PR;AS(1)GQAFELILSPR;AS(0.963)GQAFELILS(0.037)PR;AS(0.914)GQAFELILS(0.086)PR 156.17 3.2302e-08 47554600.0 22040.2 20773.510000000002 21436.7 17353.0 36369.259999999995 29427.0 31058.4 37979.1 44281.2 25912.5 True False 21725.902706322326 20725.410213915664 19674.25727405497 18629.197507911034 34230.091631516276 28168.475807687417 32666.451982081653 39743.74763552111 39293.784954291914 30391.44109876412 0.7148691184376189 0.6819489127403857 0.6473617756433087 0.612975128338636 1.126306959919326 0.9268555484469244 1.0748569597579907 1.3077283010820209 1.2929227286918556 1.0 14.891377465622133 -6.543186202516744 1.1269462591731971 1.1903892971454093 0.6502222477999506 0.7437389759916635 0.1266855683724397 0.24000617786474332 0.6460006905153325 0.06176330535770247 0.06918926990426523 2.862950225010306e-07 6.543186202516744 -0.5401670493454587 AS(ph)GVAVSDGVIK ddPTM_PC-9_AZD4547_30min_R2 2 ASGVAVSDGVIK 12 0 P23528;E9PP50;E9PS23 P23528 CFL1 Cofilin-1 1 AS(1)GVAVSDGVIK;AS(0.997)GVAVS(0.003)DGVIK 158.86 8.1305e-05 44883000.0 98239.0 89990.0 122245.0 155619.0 146634.0 127396.0 116377.0 139664.0 97934.0 118769.0 True False 129476.95850186076 119077.5076496363 120623.95142653603 119743.44383958282 126276.40018708084 119429.90798086117 126734.3275478779 118082.13795944126 103110.59130377628 114610.93346046988 1.1297086114957635 1.0389716238608857 1.052464610351857 1.0447820310344402 1.1017831927059076 1.0420463770330723 1.1057786872627597 1.0302868530441611 0.8996575474131344 1.0 16.806385152884175 -8.055054999840197 5.624950385354642 0.9520631789482841 1.070250364554754 0.6375371805004235 0.03689661843862111 0.12720263576572832 8.732701166623551 0.023530901114359064 0.00885536478456379 8.809373024470386e-09 8.055054999840197 0.11818718560647001 AS(ph)GVAVSDGVIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASGVAVSDGVIK 12 0 P23528;E9PP50;E9PS23 P23528 CFL1 Cofilin-1 1 AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK 162.72 9.068100000000001e-05 38158700.0 168483.0 148362.0 156491.0 191948.0 222062.0 177192.0 176116.0 171346.0 164113.0 135675.0 True False 197003.84420906528 163090.3988696999 160222.33893542274 181193.7758638122 178550.54518540474 167899.73959131123 159433.01751057792 166848.34905609355 166512.8421537068 160271.80349729073 1.2291859198576716 1.0175863458880763 0.9996913707789603 1.1305405686464065 1.1140483933496323 1.0475937496650771 0.9947664781426947 1.0410337028428958 1.0389403408474251 1.0 17.290161109955918 -6.957309195508132 5.640398081710077 1.021852344947347 1.0897001102944994 0.2728285422797456 0.06074967666536933 0.3066390944855962 23.760349196219877 0.022316585833962125 0.019395739316515996 1.1032928520147224e-07 6.957309195508132 0.06784776534715253 AS(ph)GVAVSDGVIK ddPTM_PC-9_Lapatinib_30min_R1 2 ASGVAVSDGVIK 12 0 P23528;E9PP50;E9PS23 P23528 CFL1 Cofilin-1 1 AS(1)GVAVSDGVIK;AS(0.999)GVAVS(0.001)DGVIK 171.99 0.00017245 41804000.0 143630.0 112332.0 138273.0 130664.0 123909.0 125169.0 123314.0 100495.0 125178.0 88175.0 True False 141581.80986148422 112071.90215565762 126904.72768921511 140273.46644232597 116620.91623446708 119815.81365319034 129698.59553996398 105164.36457503469 111079.13545722242 103415.93126419773 1.369052215947113 1.0837005554719261 1.2271293807238493 1.356400940624592 1.127688111578616 1.1585817793111166 1.2541452168391896 1.0169068081625665 1.0741008092210418 1.0 16.65809892493897 -7.76490203079088 24.999999999973543 1.0341278050095577 1.2185998288290316 0.5107348480098088 0.08722691476255132 77.34332714825906 558391.7521496285 0.044659523506134974 0.022818463780000613 1.7182959608373688e-08 7.76490203079088 0.18447202381947392 AS(ph)HSAVDITK ddPTM_PC-9_AZD4547_30min_R2 1 ASHSAVDITK 10 0 H0YJ30;G3V582;F5H039;Q9NQX3;Q9NQX3-2 H0YJ30 GPHN Gephyrin;Molybdopterin adenylyltransferase;Molybdopterin molybdenumtransferase 1 AS(0.987)HS(0.013)AVDITK 73.881 0.015188 18349000.0 56960.0 54606.0 80594.0 94367.0 81065.0 84116.0 78435.0 103010.0 86260.0 81755.0 True False 75072.09515839936 72256.32162146938 79525.27090081591 72612.14610561625 69810.52403375576 78856.21322269239 85415.56305127128 87092.17143431409 90819.52749671965 78892.78233428516 0.9515711442436299 0.9158800017383629 1.0080170650320173 0.920390230350141 0.8848784637605253 0.9995364707580242 1.0826790553456176 1.1039307888177452 1.151176632507374 1.0 16.267605697952426 -7.12760793277997 3.061587130649347 1.094410548570175 0.9381942947081658 0.6915006221187783 0.04631606607645139 0.14369645817478355 2.5613892892789845 0.01903969509393343 0.014278726545290624 7.454045977681232e-08 7.12760793277997 -0.1562162538620091 AS(ph)HSAVDITK ddPTM_PC-9_Lapatinib_30min_R1 1 ASHSAVDITK 10 0 H0YJ30;G3V582;F5H039;Q9NQX3;Q9NQX3-2 H0YJ30 GPHN Gephyrin;Molybdopterin adenylyltransferase;Molybdopterin molybdenumtransferase 1 AS(0.625)HS(0.375)AVDITK 105.36 0.0014009 14457000.0 112020.0 91544.0 107970.0 91656.0 88184.0 80047.0 84659.0 74204.0 92468.0 78127.0 True False 110422.57425804788 91332.03549244654 99093.1233762526 98396.68799545278 82997.1904964146 76623.57640867075 89042.22878033153 77651.78873502024 82053.28010879253 91631.14785231608 1.2050768417309183 0.9967356912263979 1.0814349235913006 1.0738345017137718 0.9057748641344424 0.8362175767149249 0.9717462988005218 0.8474387864285332 0.895473668419385 1.0 16.48355047146984 -6.256686398540375 5.609882157713494 0.9007036617237288 1.0831138274490553 0.6352119850323408 0.06654246639843886 0.10359171595816621 12.64256027108888 0.019296243943936458 0.023640670746563872 5.537498243335805e-07 6.256686398540375 0.18241016572532642 AS(ph)HSSERPPPR ddPTM_PC-9_Lapatinib_30min_R1 1 ASHSSERPPPR 11 1 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0 O15027 SEC16A Protein transport protein Sec16A 1 AS(0.996)HS(0.002)S(0.002)ERPPPR 67.252 0.018953 1929800.0 1723.3 2407.4 2450.3 1059.9 2520.4 2492.3 2856.2 2066.2 2748.4 1019.1 True False 1698.7254259854851 2401.8258132102146 2248.8457924315258 1137.8485817227513 2372.1550272970535 2385.710138835064 3004.080060506068 2162.203195033945 2438.8462500649466 1195.2500771346067 1.4212301329089796 2.0094755559172626 1.8814855865332567 0.9519753259088132 1.9846516412564146 1.995992457540239 2.5133485602509227 1.8089964906904097 2.040448519285298 1.0 10.223096783450988 AS(ph)ISEPSDTDPEPR ddPTM_PC-9_AZD4547_30min_R2 1 ASISEPSDTDPEPR 14 0 Q8N1F8 Q8N1F8 STK11IP Serine/threonine-protein kinase 11-interacting protein 1 AS(0.974)IS(0.021)EPS(0.004)DT(0.001)DPEPR 115.83 0.00015341 5156000.0 6508.0 6252.6 8377.0 9004.5 8908.2 8176.0 8727.6 10246.0 7622.4 8588.3 True False 8577.408625190712 8273.630673742819 8265.915506565438 6928.651643138195 7671.450196724883 7664.753427513576 9504.33949239849 8662.716129657156 8025.304502561983 8287.626231075066 1.0349656688219222 0.9983112706893356 0.9973803446361731 0.8360236634657466 0.92565108305201 0.9248430387429898 1.1468108270570008 1.045259026906361 0.9683477848543063 1.0 13.016743224132753 -7.2203678664610695 24.975025063974194 1.0438761328366695 0.9504041510648658 0.29123300395750984 0.06650459496298326 647.7285331933954 393875.1533247091 0.027073611905532032 0.020970934232284764 6.020494077972692e-08 7.2203678664610695 -0.09347198177180371 AS(ph)ISEPSDTDPEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASISEPSDTDPEPR 14 0 Q8N1F8 Q8N1F8 STK11IP Serine/threonine-protein kinase 11-interacting protein 1 AS(0.774)IS(0.226)EPSDTDPEPR 164.92 0.00050239 5118000.0 5462.8 6206.7 11234.0 10265.0 12862.0 8009.7 12338.0 9957.8 9521.8 7978.8 True False 6387.544144781873 6822.8601573486985 11501.861165182254 9689.88532957902 10341.783430639549 7589.657231729015 11169.255320615439 9696.418301161226 9661.038311524188 9425.29327985395 0.6777024284681836 0.7238883666285685 1.2203186493694425 1.0280725534865447 1.0972373085455651 0.8052436148540325 1.185030002672608 1.0287656854017255 1.0250119571530076 1.0 13.202321795012404 -5.172986913269353 7.116590385820443 1.0465651027154759 0.6936503455125723 0.6293370253930268 0.10687526481253727 0.15962438253971026 11.061698927381775 0.026448781619776287 0.07123510418247239 6.714490856051641e-06 5.172986913269353 -0.35291475720290355 AS(ph)ISEPSDTDPEPR ddPTM_PC-9_Lapatinib_30min_R1 1 ASISEPSDTDPEPR 14 0 Q8N1F8 Q8N1F8 STK11IP Serine/threonine-protein kinase 11-interacting protein 1 AS(1)ISEPSDTDPEPR 169.17 7.539100000000001e-19 0.0 9456.1 9452.7 10902.0 9703.9 10176.0 11721.0 7958.6 8968.8 11393.0 7894.1 True False 9321.254279963638 9430.812853922163 10005.679642936988 10417.557177261438 9577.46768678575 11219.720152985503 8370.657366271125 9385.523190214139 10109.800366391333 9258.584666772942 1.0067688113730389 1.0186019994791764 1.0806921363310753 1.1251781511106982 1.0344418754582665 1.211818064725449 0.9040968644280594 1.0137103594134373 1.0919379937922067 1.0 13.17657595435827 -10.24217192598976 6.749085272495658 1.0000000447565025 1.0544199055118844 0.042044698636607425 0.07751496731517792 1.0908721403563768e-10 1.655468854274745e-10 0.07498006130331655 0.018185335762479837 5.725693206805454e-11 10.24217192598976 0.054419860755381855 AS(ph)IY(ph)QNQNS(ph)S ddPTM_PC-9_AZD4547_30min_R2 1 ASIYQNQNSS 10 0 J3KMZ8;Q92785-2;Q92785;H0YEI1 J3KMZ8 DPF2 Zinc finger protein ubi-d4 3 AS(1)IY(1)QNQNS(0.649)S(0.351) 95.815 0.017397 15944000.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AS(ph)IY(ph)QNQNS(ph)S ddPTM_PC-9_Lapatinib_30min_R1 1 ASIYQNQNSS 10 0 J3KMZ8;Q92785-2;Q92785;H0YEI1 J3KMZ8 DPF2 Zinc finger protein ubi-d4 3 AS(1)IY(1)QNQNS(0.644)S(0.356) 95.741 0.017483000000000002 14521000.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AS(ph)LADALPLHIAPR ddPTM_PC-9_AZD4547_30min_R2 2 ASLADALPLHIAPR 14 0 H3BRB6;Q8ND25;Q8ND25-2 H3BRB6 ZNRF1 E3 ubiquitin-protein ligase ZNRF1 1 AS(1)LADALPLHIAPR;AS(1)LADALPLHIAPR 99.74700000000001 0.0036215 0.0 28072.0 23253.0 25929.0 34359.0 35245.0 29465.0 24904.0 33257.0 27157.0 23667.0 True False 36998.31206612689 30769.07751280134 25585.164518292357 26438.06339125828 30351.840122984268 27622.548892085055 27120.407754559314 28117.8948198329 28592.463577885675 22838.425533674148 1.6200027454420918 1.3472503814868426 1.1202683162448426 1.1576132230427463 1.3289812854319556 1.2094769340100502 1.1874902547275683 1.231166079219184 1.2519454782785915 1.0 14.479175575212746 -4.856720405701971 2.8772423479049882 1.1996811652183492 1.6589008911911611 0.715736988970636 0.08365084671432463 0.1798906155037154 2.3442083323559495 0.020807766699902842 0.17979413128597083 1.390847756454282e-05 4.856720405701971 0.4592197259728119 AS(ph)LADALPLHIAPR ddPTM_PC-9_Lapatinib_30min_R1 1 ASLADALPLHIAPR 14 0 H3BRB6;Q8ND25;Q8ND25-2 H3BRB6 ZNRF1 E3 ubiquitin-protein ligase ZNRF1 1 AS(1)LADALPLHIAPR 81.346 0.018034 0.0 7279.6 9469.9 10431.0 8466.1 5080.2 5206.2 6994.4 4870.5 8035.2 6093.8 True False 7175.791569084854 9447.97302837892 9573.40344482441 9088.72523608169 4781.392624057487 4983.542962244955 7356.535808137961 5096.801210634417 7130.191161592876 7147.105210521898 1.0040137031312655 1.3219300332209616 1.3394798541275899 1.2716652362555623 0.6689970950782099 0.6972813209616996 1.0293028563939064 0.7131280512186887 0.9976334406125544 1.0 12.803143310598898 -6.248518781376163 24.90076168229231 0.8379370272062361 1.2480483459739444 0.6078549840908075 0.15040583858873632 471.9268793707219 909503.8854119536 0.04400960383534918 0.05644545004746947 5.642625388795116e-07 6.248518781376163 0.41011131876770834 AS(ph)LEDAPVDDLTR ddPTM_PC-9_AZD4547_30min_R2 3 ASLEDAPVDDLTR 13 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 AS(1)LEDAPVDDLTR;AS(1)LEDAPVDDLTR;AS(1)LEDAPVDDLTR 237.07 5.230999999999999e-26 61603000.0 36399.7 48246.8 45996.1 39594.5 41518.0 53713.0 43632.0 55455.0 45273.0 35737.0 True False 47974.04743920626 63841.63458240335 45386.16166068215 30466.599753926963 35753.942352846076 50354.31761888902 47515.163473616005 46885.703979127204 47666.038353338685 34485.85850749621 1.3911223184070687 1.851240982402281 1.3160803768540816 0.8834519734314986 1.036771125911632 1.4601439487998675 1.3778158796101192 1.3595631951263627 1.3821908578258968 1.0 15.07371726191581 -5.449565224685627 7.822012288725575 1.228472022394749 1.6153258536135182 0.3728196986679062 0.20755873690110832 0.33576512179705853 32.27833362001329 0.057443133416083196 0.11978517889760465 3.551687733162702e-06 5.449565224685627 0.38685383121876926 AS(ph)LEDAPVDDLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ASLEDAPVDDLTR 13 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 AS(1)LEDAPVDDLTR;AS(0.981)LEDAPVDDLT(0.019)R;AS(1)LEDAPVDDLTR;AS(1)LEDAPVDDLTR 185.2 4.7305e-05 64726200.0 87489.0 133163.0 105043.0 94677.0 111756.0 80087.6 122303.0 91530.0 85034.0 78557.0 True False 102299.15971348404 146382.54259639196 107547.62349779607 89372.55463697546 89858.2140471585 75887.66526983785 110717.57444295917 89127.43448405142 86277.46138147711 92798.76224313006 1.1023763382259693 1.5774191277775231 1.1589338143974854 0.9630791669701582 0.9683126355902528 0.8177659209614712 1.1930932241626493 0.9604377507809871 0.9297264241028633 1.0 16.50181794225567 -5.544969909400126 4.515266128294637 0.9790461032730794 1.3486908884313036 0.5296443599051014 0.13775952674582892 0.1318383136311252 6.565231353104865 0.03591295630618695 0.0681200927561035 2.8512158104743015e-06 5.544969909400126 0.3696447851582242 AS(ph)LEDAPVDDLTR ddPTM_PC-9_Lapatinib_30min_R1 4 ASLEDAPVDDLTR 13 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 AS(1)LEDAPVDDLTR;AS(1)LEDAPVDDLTR;AS(1)LEDAPVDDLTR;AS(1)LEDAPVDDLTR 234.04 8.0622e-26 57912600.0 25071.6 44869.7 48215.3 32687.4 58218.6 46014.7 55539.0 54289.5 47892.7 42903.7 True False 24714.074386431665 44765.806966436125 44251.22415044025 35091.34043796984 54794.29641017148 44046.75854650476 58414.53766558589 56811.98836356372 42498.519793510946 50319.54737941323 0.4911426209795899 0.8896305570655977 0.8794042564966382 0.697369953934173 1.088926655023709 0.8753409130330374 1.1608716832275103 1.129024232575007 0.8445727755273486 1.0 15.618831324890404 -4.218782160847032 0.5092999143233342 1.029416300587226 5.436030286725026e-12 0.5161526176790606 0.13529527555755302 6.408623828980335 0.8322828889093918 0.0795146531558289 4.443794254472723 6.042516418818984e-05 4.218782160847032 -1.02941630058179 AS(ph)LEDAPVDDLTRK ddPTM_PC-9_AZD4547_30min_R2 2 ASLEDAPVDDLTRK 14 1 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 AS(1)LEDAPVDDLTRK;AS(1)LEDAPVDDLTRK 98.508 0.0011167999999999998 8631900.0 19544.6 22855.2 26087.0 28551.0 26960.0 29840.0 24974.7 32425.0 29855.0 30591.0 True False 25759.37624706553 30242.696442204353 25741.069335056985 21969.008058552805 23217.06936347441 27974.10008280396 27197.399917595285 27414.4613023749 31433.0743498095 29520.018401175745 0.8726070525091396 1.024480948189376 0.8719869000498913 0.7442071261607955 0.7864855992958901 0.9476315259237708 0.921320561118351 0.9286735844745617 1.0648053779179745 1.0 14.84940600024575 -7.8374248065159176 1.3403435425541654 1.0276227063427956 0.8713113432439118 0.38218536952553805 0.07549930327772307 0.5383205619833978 1.7569102272404502 0.07158676670540572 0.02644299897242743 1.4540361147489161e-08 7.8374248065159176 -0.15631136309888383 AS(ph)LEDAPVDDLTRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASLEDAPVDDLTRK 14 1 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 AS(1)LEDAPVDDLTRK;AS(1)LEDAPVDDLTRK 97.823 0.0011947000000000001 5896500.0 37898.3 39903.0 43594.0 47535.0 56266.0 44450.0 51253.0 43163.0 45484.0 42793.0 True False 44313.73366445534 43864.30613026009 44633.44629116567 44871.76806054933 45241.08120886058 42118.96375024713 46397.94480041357 42030.01698497879 46149.11745272594 50551.03215079842 0.8766138252580752 0.8677232543820035 0.882938377163496 0.8876528559633101 0.8949586048787735 0.8331969093054787 0.9178436685922494 0.8314373653063968 0.9129213685500791 1.0 15.62545292892079 -8.538992758881012 22.53286823090881 1.0000000007598355 0.8751802144552422 0.7039417702615491 0.024820973344901666 386.19503368951655 540032.1898651363 0.021818947621765672 0.005633628051306886 2.8907280799188847e-09 8.538992758881012 -0.12481978630459334 AS(ph)LEDAPVDDLTRK ddPTM_PC-9_Lapatinib_30min_R1 2 ASLEDAPVDDLTRK 14 1 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 AS(1)LEDAPVDDLTRK;AS(1)LEDAPVDDLTRK 152.94 0.00011831 8493200.0 27160.6 37964.0 35983.0 34399.0 44083.0 48263.0 43665.0 42299.0 45036.0 38371.0 True False 26773.284863355962 37876.096690501196 33024.616638396765 36928.8172117001 41490.124610512605 46198.90399654805 45925.76004551414 44264.36596009137 39963.57142989557 45003.37622385635 0.5949172508786887 0.8416278925851574 0.7338253128859779 0.8205788167538436 0.9219335990289242 1.0265652907182983 1.020495880510601 0.9835787817320862 0.8880127400021786 1.0 15.457745618296208 -6.148229653616177 1.6532974776753817 0.9857662364118477 0.7273015509403816 0.7493278690294074 0.06636775272087089 0.18913207153387157 1.0278286184713539 0.02302649161438585 0.03398301750243112 7.10837525505276e-07 6.148229653616177 -0.25846468547146606 AS(ph)LENVHPPIAPPPTEIPER ddPTM_PC-9_Lapatinib_30min_R1 1 ASLENVHPPIAPPPTEIPER 20 0 C9J2P9;Q75N03-2;Q75N03 C9J2P9 CBLL1 E3 ubiquitin-protein ligase Hakai 1 AS(1)LENVHPPIAPPPTEIPER 78.794 0.0073741 0.0 7512.5 9940.3 13531.0 8874.4 10850.0 14783.0 9095.1 9646.0 17868.0 9510.9 True False 7405.3703723762255 9917.283846080216 12418.533411170469 9527.052980130558 10211.824331920738 14150.765550856127 9565.999775333916 10094.188374454276 15855.51768161857 11154.846392522355 0.6638702239181359 0.8890560655974843 1.1132859184412638 0.8540729871920973 0.9154607757544944 1.2685755637425975 0.857564455728093 0.9049150494103539 1.4214017050245809 1.0 13.445383026679503 -4.316459740458745 1.1804006869967942 1.035580752529473 3.405059720791746e-14 0.30272449996793527 0.17602280089467226 5.28354888387408 2.9558840481778623 0.05234351806706484 8.787117636527995 4.8254771065114836e-05 4.316459740458745 -1.035580752529439 AS(ph)LGQASIQNGK ddPTM_PC-9_AZD4547_30min_R2 1 ASLGQASIQNGK 12 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 AS(1)LGQASIQNGK 128.96 0.00018935 2517500.0 7393.8 7051.2 11852.0 12496.0 14871.0 14564.0 12224.0 13928.0 11718.0 14220.0 True False 9744.874599406132 9330.362506268644 11694.834736040768 9615.240261275465 12806.418342144962 13653.310777679522 13311.912318974182 11775.747633599918 12337.389557228873 13722.162128231144 0.7101559148144458 0.6799484235121317 0.8522588952640724 0.700708836655825 0.9332653427696946 0.994982470698989 0.9701031218387269 0.8581554075485822 0.8990849577448641 1.0 13.744220196768543 -6.269673944671668 24.572121922190433 0.9395007586663897 0.7401016796761042 0.7476397157027964 0.05883066300692264 260.7136708905587 777974.0408161615 0.018868402630884577 0.021767144663677157 5.374351351948243e-07 6.269673944671668 -0.19939907899028553 AS(ph)LGQASIQNGK ddPTM_PC-9_Lapatinib_30min_R1 2 ASLGQASIQNGK 12 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 AS(1)LGQASIQNGK;AS(1)LGQASIQNGK 129.17 0.00018325 6365800.0 21960.0 22738.0 23171.0 19857.7 23874.0 18434.7 16440.1 18533.3 18782.5 19527.2 True False 21646.846373029206 22685.351558018545 21265.96982264658 21318.1015013453 22469.778258089926 17646.290854384595 17291.28793597289 19394.424777138025 16667.01706150664 22902.45050164154 0.9451759920397017 0.9905207111523968 0.928545607865077 0.9308218568059919 0.981108037171804 0.7704979365906628 0.7549972844492572 0.8468274945402862 0.7277394643997606 1.0 14.48321435068494 -6.759294100345748 24.99999744616499 0.8063756985120456 0.9543558347496143 0.4600056500118793 0.07250187202091621 45.44490413094894 529593.4397223842 0.022887050156183388 0.02182765462027192 1.7406277366233745e-07 6.759294100345748 0.14798013623756867 AS(ph)LGSLEGEAEAEASSPK ddPTM_PC-9_AZD4547_30min_R2 2 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 AS(0.5)LGS(0.5)LEGEAEAEASSPK;AS(0.5)LGS(0.5)LEGEAEAEASSPK 81.884 0.0016561 33005600.0 59331.9 91596.6 110056.0 160662.0 154548.0 157616.0 135799.0 146526.0 123446.0 152884.0 True False 78198.21001981437 121203.409680861 108596.58553068698 123623.85810315597 133091.67789266506 147760.24660359378 147884.84792247863 123883.77353251446 129971.10353999617 147531.57769426826 0.5300438810589121 0.8215421510100877 0.7360904507896824 0.8379484584604892 0.9021233282577158 1.001549965864253 1.0023945397570577 0.8397102197960665 0.8809714202971319 1.0 17.170664256755778 -4.150250264487969 0.583994410648027 0.9398733201798978 2.93211480604129e-16 0.7388111196770686 0.07016730107807737 4.102797514855819 0.6180806902994992 0.03660499847028775 3.0609628937292315 7.075379444096811e-05 4.150250264487969 -0.9398733201798974 AS(ph)LGSLEGEAEAEASSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 AS(0.542)LGS(0.458)LEGEAEAEASSPK 109.85 0.0001355 7154100.0 22477.0 25518.0 26436.0 35296.0 38826.0 29390.0 27470.0 25174.0 23079.0 22754.0 True False 26281.912159014082 28051.258397413163 27066.33449908829 33318.479551175944 31218.324014773083 27848.736661861927 24867.842734422582 24513.209174057774 23416.48671382162 26879.12007943511 0.9777817161180828 1.0436077637405565 1.0069650501616092 1.2395673464276649 1.1614340023971932 1.0360732263393049 0.9251732445456303 0.9119795998386322 0.8711775774139754 1.0 14.714198290068886 -7.1653536168511085 3.513525719920156 0.9185994382788109 1.0883161344331105 0.4881395677796282 0.07642911580670768 0.22246956439579146 5.150868042869341 0.03403659048758117 0.02538674268295653 6.833550105710745e-08 7.1653536168511085 0.16971669615429963 AS(ph)LGSLEGEAEAEASSPK ddPTM_PC-9_Lapatinib_30min_R1 1 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 AS(0.5)LGS(0.5)LEGEAEAEASSPK 126.09 2.4899e-05 8823300.0 123240.0 100030.0 108700.0 89445.0 91976.0 96434.0 79877.0 74431.0 102070.0 77749.0 True False 121482.57500055214 99798.38668082468 99763.10559413426 96023.08367977328 86566.15251177347 92309.74261863354 84012.64021883726 77889.33598372458 90573.8017552501 91187.81105596955 1.3322238311652002 1.0944268266245596 1.0940399208936087 1.0530254270588415 0.9493171456724695 1.0123035255443884 0.9213143647814038 0.8541638962680814 0.9932665419466798 1.0 16.476553373848127 -1.5228787452845514 0.4685474486253102 0.9369110153815619 10.658489665158768 0.8238085176021669 0.05173732279226529 36.457464787922596 0.42047848558350026 0.030752271605305956 342.94240169127255 0.029999999999708923 1.5228787452845514 9.721578649777207 AS(ph)LGTLPLGKPR ddPTM_PC-9_AZD4547_30min_R2 1 ASLGTLPLGKPR 12 1 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 AS(1)LGTLPLGKPR 79.744 0.007101100000000001 9294400.0 31879.0 24972.0 50645.0 85609.0 80204.0 77196.0 56633.0 58961.0 47599.0 79140.0 True False 42015.858875607686 33043.7106459242 49973.41420914483 65873.16769586521 69069.05902181394 72368.9219166263 61673.22728734175 49849.9322389923 50114.98596471558 76369.33268834135 0.5501666362212679 0.4326829825890137 0.6543649453254139 0.8625604726008231 0.9044083088126567 0.9476175759183273 0.8075653553112279 0.6527480401384005 0.6562187228901399 1.0 16.22070579712183 -5.535280853211525 3.5833395225564737 0.8244104987175676 0.49526022145883397 0.6122209388610171 0.10951721837277141 0.16264363152660719 4.469209547238247 0.032966476238644175 0.06651794198470383 2.9155409576514663e-06 5.535280853211525 -0.3291502772587336 AS(ph)LSSAPVVLVGDHA ddPTM_PC-9_AZD4547_30min_R2 2 ASLSSAPVVLVGDHA 15 0 Q9HBH9 Q9HBH9 MKNK2 MAP kinase-interacting serine/threonine-protein kinase 2 1 AS(0.994)LS(0.003)S(0.003)APVVLVGDHA;AS(0.911)LS(0.044)S(0.044)APVVLVGDHA 183.89 5.142899999999999e-07 8209300.0 18993.8 16615.2 17313.7 27682.0 30165.0 22411.0 21268.5 25420.0 17737.3 26097.0 True False 25033.433304417238 21985.73847205508 17084.10902542938 21300.342582636637 25977.110435801387 21009.636627202384 23161.35529745603 21491.923093488647 18674.857466584366 25183.35197330857 0.9940469136495321 0.873026692211482 0.6783890025258176 0.8458104626108759 1.031519174386877 0.8342668858962922 0.9197089935447981 0.8534178895751284 0.7415556708407025 1.0 14.62018270205916 -4.7734197348133005 5.658788436396707 0.8587701684912793 0.9989771342724688 0.13017194616865657 0.10031523490536631 0.28056718392783664 29.475045148191906 0.02535803875057112 0.14929500290252343 1.6849238012733072e-05 4.7734197348133005 0.14020696578118952 AS(ph)LSSAPVVLVGDHA ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASLSSAPVVLVGDHA 15 0 Q9HBH9 Q9HBH9 MKNK2 MAP kinase-interacting serine/threonine-protein kinase 2 1 AS(0.907)LS(0.077)S(0.015)APVVLVGDHA 96.135 0.0027032 1888900.0 11705.0 12104.0 14303.0 14920.0 17507.0 15829.0 16163.0 15976.0 13265.0 12935.0 True False 13686.425315712058 13305.605127450775 14644.037764429564 14084.080771292649 14076.629025051052 14998.899374638058 14631.92363001356 15556.6469279712 13458.97553008552 15280.013106596347 0.8957076947665483 0.8707849289544638 0.9583786127845509 0.9217322441439911 0.9212445648344505 0.9816025202336421 0.9575858036206129 1.0181042921524348 0.8808222503601983 1.0 13.899358160410902 -1.522878761350766 0.25165931789647905 0.9804758231920667 0.3173281982267376 0.3390830837323253 0.03900090099887896 53.80706243684197 0.7335610190583172 0.047718922566975776 15.13695695339377 0.029999998889894155 1.522878761350766 -0.6631476249653292 AS(ph)LSSAPVVLVGDHA ddPTM_PC-9_Lapatinib_30min_R1 2 ASLSSAPVVLVGDHA 15 0 Q9HBH9 Q9HBH9 MKNK2 MAP kinase-interacting serine/threonine-protein kinase 2 1 AS(1)LSSAPVVLVGDHA;AS(0.997)LS(0.003)SAPVVLVGDHA 217.91 7.1284e-18 4757500.0 16916.3 19954.3 17865.8 16230.9 23221.0 24041.0 20349.3 19222.2 20864.0 22922.0 True False 16675.07045993052 19908.097044338538 16396.942887982346 17424.574530695154 21855.18643424252 23012.822472308217 21402.887184110397 20115.333586091132 18514.07661233992 26884.037158354873 0.6202591657536203 0.7405173905642966 0.6099137116720803 0.6481383144971603 0.8129428740746435 0.8560032236511181 0.7961187919076702 0.7482259255782868 0.6886642993121372 1.0 14.714462182509637 -6.261878552731867 24.99742419338879 0.8053106682245179 0.6576369126896461 0.47792258632048223 0.08253208696975012 38.2933138425431 2179628.6471919566 0.02456585391793817 0.029582736060530256 5.47168953288248e-07 6.261878552731867 -0.14767375553487183 AS(ph)LT(ph)RT(ph)PPRASLT(ph)RTPSMVSLK ddPTM_PC-9_Lapatinib_30min_R1 1 ASLTRTPPRASLTRTPSMVSLK 22 3 Q9UF83 Q9UF83 Uncharacterized protein DKFZp434B061 4 AS(0.998)LT(0.998)RT(0.998)PPRAS(0.115)LT(0.834)RT(0.035)PS(0.01)MVS(0.01)LK 51.348 0.029824 0.0 6515.9 7178.4 9135.7 6421.3 7355.1 6952.5 5263.2 5085.0 9251.9 6494.4 True False 6422.982071130282 7161.778855839583 8384.598010821821 6893.543822828854 6922.487478682969 6655.157782069079 5535.702742964616 5321.267663705161 8209.853595173876 7616.948386755951 0.8432487323004983 0.9402425344370459 1.1007817809820832 0.9050269836165722 0.9088268854124726 0.8737301927423855 0.7267612253471321 0.6986088645365605 1.077840255481952 1.0 12.894997404548324 -6.481703391056005 2.1251238931467946 0.8479047057601299 0.9586324825192195 0.050229550635556675 0.12233776542072482 0.6753411450331687 6.085608104515005 0.04468983766089713 0.04957446870378568 3.298349017332808e-07 6.481703391056005 0.11072777675908962 AS(ph)LTLEEK ddPTM_PC-9_AZD4547_30min_R2 1 ASLTLEEK 8 0 A0A0U1RQQ9;Q6P3W7 A0A0U1RQQ9 SCYL2 SCY1-like protein 2 1 AS(0.998)LT(0.002)LEEK 93.556 0.0071363 4268200.0 22720.0 22657.0 24245.0 32129.0 28787.0 31642.0 23125.0 32886.0 20726.0 24189.0 True False 29944.48739464245 29980.432168216597 23923.495458598405 24722.155438101745 24790.42194978998 29663.420737938413 25183.080200938995 27804.224345101018 21821.534047032375 23342.150472558584 1.2828504138830603 1.2843903222825201 1.024905373938158 1.0591207295645497 1.062045332067155 1.2708092501079205 1.078867186232247 1.191159502539756 0.9348553413142516 1.0 14.51064985975403 -5.24900723078129 24.267185242357247 1.090260363629346 1.283620428299433 0.45037632933534777 0.09013557925004256 484.1205336893583 944981.9914850227 0.022675017308654254 0.058997575968195895 5.636282716250075e-06 5.24900723078129 0.19336006467008704 AS(ph)LTLEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASLTLEEK 8 0 A0A0U1RQQ9;Q6P3W7 A0A0U1RQQ9 SCYL2 SCY1-like protein 2 1 AS(1)LTLEEK 115.23 0.0036428000000000003 3311900.0 15959.0 21043.0 16719.0 15519.0 16895.0 14141.0 16354.0 15401.0 12105.0 13401.0 True False 18660.543495382204 23132.00997165785 17117.64436716059 14649.520743276838 13584.546031772286 13399.421066192226 14804.830727293303 14996.740068708355 12282.012724589918 15830.495217742371 1.1787719359826467 1.4612309756255855 1.0813082049369889 0.925398766227987 0.8581251467450691 0.8464309474775328 0.9352095764319784 0.9473323394141475 0.7758451365958903 1.0 13.95041876686321 -5.537111770587019 3.158323740470779 0.8940037376545668 1.3191644604081891 0.7842411693491086 0.08786139072622512 0.09606725202001432 1.9668748206013846 0.02303879129707983 0.04800163263062387 2.9032753676206277e-06 5.537111770587019 0.4251607227536224 AS(ph)LTLEEK ddPTM_PC-9_Lapatinib_30min_R1 2 ASLTLEEK 8 0 A0A0U1RQQ9;Q6P3W7 A0A0U1RQQ9 SCYL2 SCY1-like protein 2 1 AS(0.996)LT(0.004)LEEK;AS(1)LTLEEK 123.86 0.0032984999999999998 8262600.0 68142.0 63017.0 69739.0 65519.0 70722.0 78386.0 63358.0 65567.0 74603.0 67260.0 True False 67170.28258428775 62871.088008252955 64005.328620324966 70337.48582497693 66562.27100480176 75033.61350669073 66638.3672269252 68613.48218410173 66200.42453558256 78885.80138168352 0.8514876113039527 0.7969886457013414 0.811366906328803 0.8916368293535342 0.8437801206169511 0.9511675382955896 0.8447447583691271 0.8697824067492211 0.8391931548654283 1.0 16.26747803315194 -14.522878745280336 0.1608783887754726 1.5149142292006514 0.8196003821832538 0.5363806447190671 0.040478647689656824 109.32711496400835 1.0040902577182995 18.106340555202188 0.175653346539148 3.0000000000000132e-15 14.522878745280336 -0.6953138470173976 AS(ph)LVSEEEEDEEEDK ddPTM_PC-9_AZD4547_30min_R2 1 ASLVSEEEEDEEEDK 15 0 Q96GN5-5;Q96GN5-4;Q96GN5-2;Q96GN5;C9J8L0;C9IZR6;C9JFL7 Q96GN5-5 CDCA7L Cell division cycle-associated 7-like protein 1 AS(0.5)LVS(0.5)EEEEDEEEDK 77.77600000000001 0.012575 69900000.0 3380.0 3781.8 49315.0 41434.0 36149.0 51818.0 17405.0 70167.0 31357.0 37222.0 True False 4454.769691632547 5004.192892870261 48661.05087815142 31882.031448918642 31130.335327160123 48577.81226845627 18954.011282047268 59324.30242725486 33014.46700341573 35918.86910949506 0.12402310546171788 0.1393193331787669 1.3547489685661622 0.8876123396794446 0.8666847286383773 1.3524315623738512 0.5276895334390365 1.6516194384185838 0.9191399345779636 1.0 15.132454307696243 -5.250071335293569 24.603619858297193 1.0702077506906824 0.13167098534028362 0.6113342730218756 0.29926743057326904 361.8443623091739 783127.5018097351 0.07171459576355062 0.18599746793843255 5.622489650733509e-06 5.250071335293569 -0.9385367653503988 AS(ph)LVSEEEEDEEEDK ddPTM_PC-9_Lapatinib_30min_R1 1 ASLVSEEEEDEEEDK 15 0 Q96GN5-5;Q96GN5-4;Q96GN5-2;Q96GN5;C9J8L0;C9IZR6;C9JFL7 Q96GN5-5 CDCA7L Cell division cycle-associated 7-like protein 1 AS(0.5)LVS(0.5)EEEEDEEEDK 78.234 0.006860300000000001 286490000.0 52514.0 24327.0 211290.0 39418.0 127390.0 159760.0 55887.0 93252.0 209370.0 74847.0 True False 51765.14073011182 24270.672326146436 193918.55180298616 42316.93121459328 119897.17065837618 152927.43721874963 58780.55540280881 97584.82835316277 185788.54583615853 87784.20422264162 0.5896862788528915 0.2764810883811197 2.209036961947762 0.4820563288045247 1.3658171389728435 1.7420837674952236 0.6696028735844929 1.1116445061763554 2.1164234212906297 1.0 16.421673745963787 -5.21606901767331 24.999825608228974 1.3021862873729044 0.4330829638120634 0.3067965300647211 0.5415132907282932 529.2292369571153 291612.3965650977 0.13202949030106254 0.34931428660561786 6.08038364711385e-06 5.21606901767331 -0.869103323560841 AS(ph)LYNAVTIEDVQK ddPTM_PC-9_AZD4547_30min_R2 2 ASLYNAVTIEDVQK 14 0 Q9Y617-2;Q9Y617 Q9Y617-2 PSAT1 Phosphoserine aminotransferase 1 AS(1)LYNAVTIEDVQK;AS(1)LYNAVTIEDVQK 167.05 0.00041121 5513600.0 15786.1 19315.2 21358.0 21656.7 18180.5 23790.0 23480.9 23513.0 24658.0 21971.0 True False 20805.751428722044 25558.46067067736 21074.778964930705 16664.08240767961 15656.45139327325 22302.407539205968 25570.65461146933 19879.60612498816 25961.3715396953 21201.801977451934 0.9813199581266211 1.205485302516207 0.9940088577067026 0.7859748159803502 0.7384490907859553 1.0519109443114565 1.2060604395165873 0.9376375718502642 1.224488916899854 1.0 14.371899266670656 -8.242573318245265 24.7997862262036 1.112244513512961 0.989481013825158 0.09747979491944825 0.15161342106503 1740.0424426221173 2287327.480478068 0.11213941149806275 0.04221783360731144 5.72040373786935e-09 8.242573318245265 -0.12276349968780309 AS(ph)LYNAVTIEDVQK ddPTM_PC-9_Lapatinib_30min_R1 2 ASLYNAVTIEDVQK 14 0 Q9Y617-2;Q9Y617 Q9Y617-2 PSAT1 Phosphoserine aminotransferase 1 AS(1)LYNAVTIEDVQK;AS(1)LYNAVTIEDVQK 177.66 1.0398e-18 2298000.0 17641.3 27247.0 25943.0 24090.0 31125.0 28730.0 27801.0 24758.0 23562.0 17743.3 True False 17389.731826981806 27183.911245550684 23810.06668287602 25861.65896188422 29294.28869410443 27501.284872901077 29240.39974866229 25908.347063522593 20908.1994411404 20810.205763538866 0.8356347853825644 1.3062778693509631 1.1441533521303835 1.2427392240011341 1.4076885652630284 1.3215287338045216 1.40509902116844 1.2449827434631173 1.0047089240113727 1.0 14.345003609522722 -4.756673371819011 24.94272080753806 1.2499289788592272 0.8356341384673549 0.41795105786487863 0.13824963005864466 135.46940180104215 708887.4967203037 0.03435761639331115 0.27257652346935235 1.7511632244007987e-05 4.756673371819011 -0.41429484039187225 AS(ph)MAGASSSK ddPTM_PC-9_AZD4547_30min_R2 2 ASMAGASSSK 10 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 AS(1)MAGASSSK;AS(1)MAGASSSK 78.548 0.017827000000000003 6581200.0 38429.0 34732.0 38287.0 57326.0 41301.0 53967.0 41949.0 42967.0 36263.0 36042.0 True False 50648.62262714412 45958.439778721746 37779.2893637186 44110.37637787108 35567.06905715346 50592.43495873595 45682.379734019014 36327.43743343536 38179.78814761823 34780.18055033102 1.4562495601151235 1.3213973893037867 1.0862303980580985 1.268261857181511 1.0226246239775472 1.454634051871086 1.3134601089235645 1.0444867409720684 1.097745541957943 1.0 15.085977801509392 -1.5228789868411996 0.04828087523115601 0.5346866838466585 2.428068962059629 0.3246058753829133 0.1378594821556076 727.4429187879065 2.6655364157818133 25.302760987311963 104.11034872170026 0.02999998331357144 1.5228789868411996 1.8933822782129703 AS(ph)MAGASSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASMAGASSSK 10 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 AS(1)MAGASSSK 64.64 0.044813 2095800.0 22279.0 26439.0 17192.0 16694.0 16478.0 10478.0 16449.0 9889.8 13003.0 12372.0 True False 26050.39466969235 29063.68919073619 17601.922481023084 15758.689302678253 13249.254188312745 9928.515234535202 14890.831639552862 9630.20322910926 13193.144275740819 14614.945663301894 1.7824489580624887 1.9886279333706363 1.2043782362613558 1.0782584941282605 0.9065551452292842 0.6793398664126195 1.0188769758442358 0.6589284319606254 0.9027159306427518 1.0 13.835156844928063 -5.476502774684268 1.737702374061446 0.8546037366111782 1.933720345246637 0.8804476206893674 0.14366211876261703 0.11278758033283856 0.6450557261810712 0.04082282782970564 0.1257822758069092 3.3380837247529916e-06 5.476502774684268 1.0791166086354589 AS(ph)NETLVSCSSSGSDQQR ddPTM_PC-9_Lapatinib_30min_R1 1 ASNETLVSCSSSGSDQQR 18 0 A0A087WYH0;J3KRC8;Q96N06;Q96N06-2 A0A087WYH0 SPATA33 Spermatogenesis-associated protein 33 1 AS(1)NETLVSCSSSGSDQQR 128.66 1.781e-05 0.0 20682.0 35067.0 48323.0 42287.0 45203.0 37885.0 25282.0 30326.0 36213.0 27947.0 True False 20387.070887385704 34985.80451601005 44350.06947217426 45396.92704529669 42544.248412517336 36264.74686424843 26590.978254223937 31735.05667050596 32134.31060020447 32777.60171296327 0.6219817748082157 1.0673692609478949 1.3530602348686842 1.384998434078311 1.297967093049747 1.106388050651858 0.8112545416557254 0.9681933702292506 0.9803740640211519 1.0 15.000422678056596 -7.0644792703695245 7.064653737717527 0.9389487318045394 1.1692426082057998 0.17801091233571498 0.20722908171481225 0.45823864972271844 43.14584063455698 0.08556001583115189 0.0665426868044324 8.620267237576159e-08 7.0644792703695245 0.23029387640126042 AS(ph)NPDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASNPDLR 7 0 Q8N4C8-3;Q8N4C8-2;Q8N4C8-5;Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5;Q9UKE5-8;Q9UKE5-5;Q9UKE5-7;Q9UKE5-3 Q8N4C8-3;Q9UKE5-6 MINK1;TNIK Misshapen-like kinase 1;TRAF2 and NCK-interacting protein kinase 1 AS(1)NPDLR 70.399 0.044085 7890500.0 47630.0 86550.0 72416.0 48574.0 73090.0 48863.0 65965.0 47166.0 40723.0 42105.0 True False 55692.81826461896 95142.11201097665 74142.67207920944 45852.55625903277 58768.539180955115 46300.538261604604 59716.31765475737 45927.94247650788 41318.496834653044 49738.30319700339 1.1197168919098615 1.912853995725144 1.4906554368279366 0.9218761660891414 1.181554966766453 0.9308829470562658 1.2006102704837571 0.9233918232915297 0.8307178608606491 1.0 15.60206967095984 -5.715242305467241 6.366267843777652 1.0084951095133998 1.5555205882976662 0.55065538345084 0.2096645692856119 0.13182306997925872 12.633780282703576 0.05464195809811349 0.09411194887076701 1.926449791175617e-06 5.715242305467241 0.5470254787842663 AS(ph)PAAPADGAAPAQPSIR ddPTM_PC-9_AZD4547_30min_R2 2 ASPAAPADGAAPAQPSIR 18 0 Q9P1Y5 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 AS(1)PAAPADGAAPAQPSIR;AS(1)PAAPADGAAPAQPSIR 180.14 3.53e-09 4723800.0 10817.2 12105.900000000001 11991.0 13122.2 12519.8 14025.9 10494.8 13067.3 13632.0 10943.7 True False 14256.844588262591 16018.895431222718 11831.991505219787 10097.079525969024 10781.641877478738 13148.858255743971 11428.816868878466 11048.049041681526 14352.559689720414 10560.564394003033 1.3500078268883569 1.516859784531902 1.1203938600041823 0.956111733166723 1.0209342488931035 1.2450904861875316 1.0822164841273523 1.0461608517775165 1.3590712725420926 1.0 13.36639931904418 -5.273688205057253 22.60274391891456 1.1014445991326702 1.433433775648618 0.5493906986397996 0.11941737356594119 131.5903882576915 242825.2079074104 0.031024482486497047 0.06555072203157605 5.324904152489024e-06 5.273688205057253 0.3319891765159477 AS(ph)PAAPADGAAPAQPSIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASPAAPADGAAPAQPSIR 18 0 Q9P1Y5 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 AS(1)PAAPADGAAPAQPSIR 99.37100000000001 0.00065337 3737400.0 7955.4 12542.0 9482.2 10149.0 8176.4 7381.2 10174.0 7337.4 6013.5 6023.1 True False 9302.092093687796 13787.086872809614 9708.291609443753 9580.38443350195 6574.293114778511 6994.116878140027 9210.245066618694 7144.801024617926 6101.43606107571 7115.040351166634 1.3073843062833168 1.937738395334467 1.3644745679976238 1.3464975545684825 0.9239994139598298 0.9830045274435051 1.2944754508818093 1.0041827835096413 0.8575406125525732 1.0 12.796656223320088 -5.87637683020433 1.9510769012858302 1.025474949138349 1.6119173176634425 0.6138503939030449 0.18971591350937586 0.20970471019313439 1.6267487277164427 0.0582213506504922 0.10389795684870301 1.329300505172334e-06 5.87637683020433 0.5864423685250935 AS(ph)PAAPADGAAPAQPSIR ddPTM_PC-9_Lapatinib_30min_R1 1 ASPAAPADGAAPAQPSIR 18 0 Q9P1Y5 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 AS(1)PAAPADGAAPAQPSIR 175.19 2.3519e-08 4964700.0 3633.0 7983.5 8972.2 5465.3 11255.0 7866.8 7358.0 12815.0 8364.9 5869.3 True False 3581.1927537893966 7965.01469625478 8234.540349693565 5867.236393706343 10593.00302818137 7530.355302406483 7738.961237029498 13410.431683457555 7422.756875697957 6883.800684649343 0.5202348118206477 1.1570664319227764 1.1962200428109908 0.852325141660492 1.538830584070139 1.0939240758668298 1.1242279652702811 1.948114464348509 1.0782934044343366 1.0 12.748989610478489 -4.591440708812714 1.8871745788258882 1.2573615361671313 1.1920351498235216e-50 0.3346798354744297 0.29488741549530917 1.7794720934043444 4.342137502868542 0.07918111310770268 4.66684559496961 2.561882996176678e-05 4.591440708812714 -1.2573615361671313 AS(ph)PALVAK ddPTM_PC-9_AZD4547_30min_R2 3 ASPALVAK 8 0 A6NMU3;Q92783-2;Q92783 A6NMU3 STAM Signal transducing adapter molecule 1 1 AS(1)PALVAK;AS(1)PALVAK;AS(1)PALVAK 95.523 0.0064005 41066000.0 142990.0 161050.0 211682.0 232519.0 209800.0 222872.0 191669.0 268446.0 184335.0 202206.0 True False 188457.84562323565 213106.26299559875 208874.9583694381 178915.33693273933 180672.89141160762 208935.77860773052 208727.1696879466 226963.8389753992 194078.57177263874 195126.82948671596 0.9658223121801182 1.0921422930725517 1.0704573990101043 0.9169181777994282 0.9259254193125075 1.070769094938606 1.0697000009532596 1.1631605944319958 0.9946278135260298 1.0 17.574052633246218 -6.889819026098763 24.5537424472594 1.0704943107497606 0.999495630080017 0.17714577831602596 0.06804226389790083 12.478202260271207 2724.035952851174 0.025187121480809885 0.022212953991892978 1.2887864872037976e-07 6.889819026098763 -0.07099868066974369 AS(ph)PALVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASPALVAK 8 0 A6NMU3;Q92783-2;Q92783 A6NMU3 STAM Signal transducing adapter molecule 1 1 AS(1)PALVAK 99.01299999999999 0.0053299 11785000.0 60706.0 52899.0 65172.0 67938.0 77481.0 75919.0 74778.0 57974.0 56993.0 56522.0 True False 70982.32680184684 58150.463122688234 66725.9476461863 64131.654117967824 62299.15425201234 71937.67399223878 67694.48649416285 56452.24392853049 57826.41480483708 66768.9911720943 1.063103179421909 0.8709201996598664 0.9993553365843574 0.9605005705818012 0.9330551976057098 1.0774114260139471 1.013861154793894 0.8454859499528333 0.8660669240275308 1.0 16.026890621936822 -7.7550122316608245 24.999874990269284 0.8918323236625386 0.9844563082588385 0.23688691635967918 0.06821371797140911 194.65868014039572 757177.9403270822 0.03249390294386316 0.018176218162477758 1.757874103721976e-08 7.7550122316608245 0.09262398459629984 AS(ph)PALVAK ddPTM_PC-9_Lapatinib_30min_R1 2 ASPALVAK 8 0 A6NMU3;Q92783-2;Q92783 A6NMU3 STAM Signal transducing adapter molecule 1 1 AS(1)PALVAK;AS(1)PALVAK 93.667 0.007053 23288000.0 114773.0 156282.0 151645.0 142027.0 145588.0 139107.0 127040.0 129151.0 137555.0 102191.0 True False 113136.31597320976 155920.1386309377 139177.33346662784 152472.13936818304 137024.80007702103 133157.71788425514 133617.5095885059 135151.82694890565 122062.10738163424 119854.57818905146 0.943946553253521 1.3009109955315896 1.1612183328291208 1.2721428056563895 1.143258790339125 1.1109940053705758 1.1148302518552575 1.1276317433258596 1.0184183969101352 1.0 16.870925492347446 -8.035211944912698 0.7968278945481082 0.9962748223431106 1.1731839374744748 0.26225672698951896 0.09170409918872875 0.772140782860609 0.9833314601053033 0.08291518746788654 0.03405975496726998 9.221213025871125e-09 8.035211944912698 0.1769091151313642 AS(ph)PAPGSGHPEGPGAHLDMNSLDR ddPTM_PC-9_AZD4547_30min_R2 6 ASPAPGSGHPEGPGAHLDMNSLDR 24 0 O94826 O94826 TOMM70A Mitochondrial import receptor subunit TOM70 1 AS(0.995)PAPGS(0.005)GHPEGPGAHLDMNSLDR;AS(0.997)PAPGS(0.003)GHPEGPGAHLDMNSLDR;AS(0.945)PAPGS(0.055)GHPEGPGAHLDMNSLDR;AS(0.614)PAPGS(0.386)GHPEGPGAHLDMNSLDR;AS(0.785)PAPGS(0.215)GHPEGPGAHLDMNSLDR;AS(0.778)PAPGS(0.222)GHPEGPGAHLDMNSLDR 102.16 2.2726e-06 449232000.0 68840.0 69349.2 239414.0 308689.0 226371.0 158323.6 186037.3 289976.0 164782.1 123295.4 True False 90729.6880390488 91764.97270247992 236239.21392967156 237525.5202475084 194943.2940978881 148423.6002637339 202594.2592979959 245166.87218558125 173492.14539667557 118978.86557419895 0.7625697858286178 0.7712712023233438 1.9855561135968756 1.9963673304598792 1.6384699346146931 1.2474786975605539 1.7027751804512858 2.0605917782321392 1.4581761606096373 1.0 16.86034580226265 -5.248667761361616 24.546992486603585 1.6754974400215132 0.7669202425446826 0.5359026044428978 0.3219114719721198 434.58504541392307 835265.6295616855 0.08165536954069706 0.21286223794657505 5.6406900796582125e-06 5.248667761361616 -0.9085771974768306 AS(ph)PAPGSGHPEGPGAHLDMNSLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 ASPAPGSGHPEGPGAHLDMNSLDR 24 0 O94826 O94826 TOMM70A Mitochondrial import receptor subunit TOM70 1 AS(0.954)PAPGS(0.046)GHPEGPGAHLDMNSLDR;AS(0.985)PAPGS(0.015)GHPEGPGAHLDMNSLDR;AS(0.95)PAPGS(0.05)GHPEGPGAHLDMNSLDR;AS(0.987)PAPGS(0.013)GHPEGPGAHLDMNSLDR;AS(0.507)PAPGS(0.493)GHPEGPGAHLDMNSLDR;AS(0.592)PAPGS(0.407)GHPEGPGAHLDMNS(0.001)LDR;AS(0.726)PAPGS(0.274)GHPEGPGAHLDMNSLDR 83.064 4.3017e-05 283950200.0 121854.9 104392.6 182977.0 148493.8 265541.0 179963.0 157519.3 137198.3 152118.7 114885.5 True False 142482.5278260194 114756.00742134122 187339.86562413644 140174.1738093953 213510.1472520184 170525.42347324474 142597.93156302662 133596.9899986148 154343.1482071934 135713.3317168824 1.0498786377395737 0.8455765249411075 1.38040871338237 1.032869593842253 1.5732437230074887 1.2565119529228372 1.050728987042382 0.9844057935097886 1.1372732969902726 1.0 17.05020292442793 -7.3077783548326485 9.974540478049322 1.0415974854158871 1.1930439787274854 0.12379102411719212 0.19099940398388915 1.5041091157778086 317.41191948185576 0.0840221533361367 0.05670695465876526 4.9229071552325525e-08 7.3077783548326485 0.1514464933115982 AS(ph)PAPGSGHPEGPGAHLDMNSLDR ddPTM_PC-9_Lapatinib_30min_R1 9 ASPAPGSGHPEGPGAHLDMNSLDR 24 0 O94826 O94826 TOMM70A Mitochondrial import receptor subunit TOM70 1 AS(0.992)PAPGS(0.008)GHPEGPGAHLDMNSLDR;AS(0.98)PAPGS(0.02)GHPEGPGAHLDMNSLDR;AS(0.761)PAPGS(0.239)GHPEGPGAHLDMNSLDR;AS(0.975)PAPGS(0.025)GHPEGPGAHLDMNSLDR;AS(0.939)PAPGS(0.061)GHPEGPGAHLDMNSLDR;AS(0.702)PAPGS(0.298)GHPEGPGAHLDMNSLDR;AS(0.689)PAPGS(0.311)GHPEGPGAHLDMNSLDR;AS(0.859)PAPGS(0.141)GHPEGPGAHLDMNSLDR;AS(0.788)PAPGS(0.212)GHPEGPGAHLDMNSLDR 87.485 1.2479e-05 226659400.0 199203.6 184937.5 150523.3 124022.3 122608.6 133889.0 110412.0 116114.3 193471.6 87389.60000000002 True False 196362.92013453352 184509.28858127637 138147.85531074103 133143.3136682645 115397.00320578217 128162.87958050311 116128.59310993498 121509.39427409228 171680.79106173263 102494.77592067771 1.915833449760423 1.8001823695294574 1.3478526497551035 1.2990253646810856 1.1258818039183742 1.2504332872505652 1.1330196301888469 1.1855179269637144 1.6750199170599587 1.0 16.645190852992904 -5.255623607635509 2.2254139445000174 1.2370061192084911 1.9267459838146017 0.6852586390668143 0.16665468174585457 0.18626772425829638 1.7064113415930908 0.04531304953747406 0.16663812856191393 5.551066018031125e-06 5.255623607635509 0.6897398646061106 AS(ph)PDSSSCGER ddPTM_PC-9_Lapatinib_30min_R1 1 ASPDSSSCGER 11 0 Q9BRK4 Q9BRK4 LZTS2 Leucine zipper putative tumor suppressor 2 1 AS(1)PDSSSCGER 100.82 0.0039897 1385300.0 8903.5 9958.4 8795.6 7348.5 7603.0 8106.0 9112.8 9863.2 10631.0 7324.7 True False 8776.534457298072 9935.34193664227 8072.459719997848 7888.933203877382 7155.806488073121 7759.325276008918 9584.616194727156 10321.480279381858 9433.624830607067 8590.764635450745 1.0216243640386475 1.156514275300126 0.939667196408332 0.9183039622949071 0.8329650260168798 0.903217071503647 1.1156883701801317 1.2014623514173723 1.0981123602988918 1.0 13.068570831238654 -7.277685781503891 22.76080342258616 1.1206043767893559 0.9620148330543782 0.3551924128532036 0.09247589214378278 293.93304573722554 411788.95193693525 0.04275999011779156 0.028963305471296656 5.276114580725594e-08 7.277685781503891 -0.1585895437349777 AS(ph)PEPEGEAAGK ddPTM_PC-9_AZD4547_30min_R2 2 ASPEPEGEAAGK 12 0 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 AS(1)PEPEGEAAGK;AS(1)PEPEGEAAGK 139.78 7.3452e-05 22753800.0 79546.0 78008.0 89747.0 108368.0 108724.0 104348.0 97076.0 105344.0 94709.0 94132.0 True False 104839.97334041499 103222.56047041707 88556.89614035195 83385.43186891009 93629.54931284832 97823.10306435729 105715.57593886954 89065.50536429846 99715.12438774446 90836.46733155103 1.1541617196290943 1.1363559537565138 0.974904669257131 0.917973081940265 1.0307484654935182 1.076914436878145 1.163801048680263 0.9805038436733938 1.0977433107761285 1.0 16.470983979667842 -6.759726249977865 24.51909936443819 1.0688245517214308 1.0373147411737382 0.012631437140765645 0.08006409081276519 172.13632242040924 2463679.360697619 0.02945266199474782 0.027989522643197717 1.73889656677637e-07 6.759726249977865 -0.03150981054769253 AS(ph)PEPEGEAAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASPEPEGEAAGK 12 0 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 AS(1)PEPEGEAAGK;AS(1)PEPEGEAAGK 118.76 0.00056982 24231000.0 83078.0 75232.0 86323.0 90282.0 106267.0 79944.0 91392.0 69750.0 83226.0 64417.0 True False 97141.46453470536 82700.53576903323 88381.2677018007 85223.79223819311 85444.74419404245 75751.59590663126 82734.68813921901 67919.1364062339 84443.02280187698 76095.29217530871 1.2765765365735158 1.086802263384538 1.1614551331005798 1.1199614299640788 1.1228650518509662 0.9954833438593594 1.0872510739378518 0.8925537239512985 1.1097010128739204 1.0 16.21551958011885 -1.5228787452803672 0.2452337034976308 0.9841378078723438 2.535854847889828 0.5224610437590327 0.06844266275199522 38.85707756747969 0.5241296822701792 0.08666384712806448 24.71304672943835 0.029999999999997955 1.5228787452803672 1.5517170400174845 AS(ph)PEPEGEAAGK ddPTM_PC-9_Lapatinib_30min_R1 1 ASPEPEGEAAGK 12 0 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 AS(1)PEPEGEAAGK 141.34 5.913100000000001e-05 7792300.0 48306.0 56818.0 72715.0 64379.0 60947.0 66290.0 62899.0 61915.0 72872.0 60884.0 True False 47617.147581764526 56686.4414118875 66736.65338801726 69113.6464220482 57362.21728641227 63454.93122953745 66155.60245282926 64791.7969318201 64664.387983820736 71407.71827716951 0.6668347446271602 0.7938419372519189 0.9345859943175684 0.9678736149190925 0.803305562344962 0.8886284670690181 0.9264489056497489 0.9073500525577688 0.9055658063855998 1.0 16.123792399439562 -4.9564286153520465 2.689030014300223 0.9102164165408725 0.6584017290727077 0.7172463359992723 0.0497336103818656 0.1782928331139265 2.2333559685689135 0.013158645420460281 0.085099307544871 1.1055321699168057e-05 4.9564286153520465 -0.2518146874681648 AS(ph)PEPPDSAEGALK ddPTM_PC-9_AZD4547_30min_R2 4 ASPEPPDSAEGALK 14 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 AS(0.99)PEPPDS(0.01)AEGALK;AS(1)PEPPDSAEGALK;AS(1)PEPPDSAEGALK;AS(1)PEPPDSAEGALK 158.31 7.6855e-05 76738400.0 69136.2 62098.4 84185.2 96267.4 97434.0 83114.7 83045.3 99462.0 75277.2 87827.5 True False 91120.07347770598 82170.493399602 83068.84924236752 74074.43824650362 83906.97093326302 77917.5246699807 90436.17081993692 84092.43330938512 79256.19911055031 84752.68595761049 1.0751290351232075 0.969532616827035 0.980132349833902 0.8740069699213113 0.9900213779092445 0.9193516853135671 1.067059642984873 0.9922096551777061 0.9351467533452653 1.0 16.37097146999691 -7.2307236089040146 24.998870220263957 0.9979548907461346 0.9653734387344874 0.06410581930192039 0.05666771031757123 2049.3194148037805 1667896.9180725426 0.021909604926610732 0.01696989965863608 5.878633579873652e-08 7.2307236089040146 -0.032581452011647194 AS(ph)PEPPDSAEGALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ASPEPPDSAEGALK 14 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 AS(1)PEPPDSAEGALK;AS(1)PEPPDSAEGALK;AS(1)PEPPDSAEGALK;AS(1)PEPPDSAEGALK 196.84 1.0555e-07 57229300.0 163322.0 175012.0 183459.0 207554.0 230875.0 174171.0 189806.0 172392.0 163062.0 140736.0 True False 190969.18884346224 192386.0347459861 187833.3583321319 195925.42227914653 185636.70110005455 165037.1661494779 171826.20160356053 167866.8926644226 165446.47326700395 166250.3227344373 1.1486846202909935 1.157206985115434 1.129822518493216 1.1784964928586108 1.1166095683109403 0.9927028316997781 1.0335390559092625 1.0097237100259202 0.995164824619815 1.0 17.34299761569377 -6.658814448593139 4.189736744975921 1.008484861853153 1.1516581883427661 0.950620161650906 0.01608157413323341 0.04343098530514963 1.380665637583101 0.0053320508453918395 0.005274977971891937 2.1937420068283482e-07 6.658814448593139 0.14317332648961312 AS(ph)PEPPDSAEGALK ddPTM_PC-9_Lapatinib_30min_R1 4 ASPEPPDSAEGALK 14 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 AS(1)PEPPDSAEGALK;AS(0.999)PEPPDS(0.001)AEGALK;AS(1)PEPPDSAEGALK;AS(1)PEPPDSAEGALK 165.78 0.00010506 56655500.0 110876.5 143704.2 158109.9 158763.1 153788.6 142091.8 137496.6 144192.3 158210.4 120603.2 True False 109295.38077774 143371.46175405997 145110.71434386386 170439.06799217637 144743.05690802066 136014.86494616367 144615.50117196917 150892.00065787107 140391.07872262946 141449.30242633753 0.7726823597073424 1.013589033630784 1.025884976841318 1.2049480984958256 1.0232857598106462 0.9615803161489329 1.0223839827508552 1.066756767757487 0.9925187068047991 1.0 17.109925536370376 -4.752218219583065 3.7513070723297117 1.0408952831458602 0.7353919529481536 0.615543925659408 0.06227183807371755 0.20540392675494984 4.899700124554093 0.016485271021666248 0.18243215843920765 1.7692197565747947e-05 4.752218219583065 -0.3055033301977066 AS(ph)PEPPGPESSSR ddPTM_PC-9_AZD4547_30min_R2 3 ASPEPPGPESSSR 13 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 AS(1)PEPPGPESSSR;AS(0.999)PEPPGPESSSR;AS(1)PEPPGPESSSR 160.48 0.00028826 844707000.0 79008.0 77708.0 89250.0 85581.0 90892.0 93461.0 81499.0 98100.0 91411.0 79546.0 True False 104130.90053151014 102825.5913372369 88066.48668508601 65851.62266326947 78273.21471012315 87616.86889540672 88752.25311551691 82940.89911373884 96242.79884074484 76761.11875191807 1.35655788014304 1.3395530577082364 1.1472798744596913 0.8578773177615263 1.0196987222540617 1.1414225107710196 1.1562136477238252 1.0805066479267065 1.253796197939598 1.0 16.228088117738324 -5.324372430284785 3.9944136258868754 1.0759426507169163 1.3519584398888336 0.5380758574897765 0.1001116613209209 0.1706879276325518 5.430116864422193 0.028355452069594833 0.06666046637118359 4.738354722252372e-06 5.324372430284785 0.27601578917191727 AS(ph)PEPPGPESSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASPEPPGPESSSR 13 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 AS(1)PEPPGPESSSR;AS(1)PEPPGPESSSR;AS(1)PEPPGPESSSR 127.78 0.00011298 731096000.0 78276.0 101621.0 89042.0 90058.0 102624.0 83322.0 93285.0 66587.0 73673.0 74127.0 True False 91526.5807785287 111709.26129020775 91165.09897366542 85012.3422319755 82515.563892548 78952.44764000211 84448.36947508615 64839.16180475836 74750.32824937718 87565.63831099082 1.045233981547311 1.2757202876026605 1.041105857641225 0.9708413468083538 0.942328126467743 0.9016373221605624 0.9644007752808968 0.7404635317620937 0.8536490990210127 1.0 16.418077231526233 -5.811284572414149 1.3292702012922983 0.8836170784931895 1.166393304342119 0.5756931660813515 0.08657627619027312 0.3035158927312022 1.0772387722678298 0.029781211243657735 0.0688456635318235 1.5442422398286203e-06 5.811284572414149 0.2827762258489296 AS(ph)PEPPGPESSSR ddPTM_PC-9_Lapatinib_30min_R1 3 ASPEPPGPESSSR 13 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 AS(1)PEPPGPESSSR;AS(0.992)PEPPGPES(0.003)S(0.003)S(0.002)R;AS(0.965)PEPPGPES(0.013)S(0.013)S(0.008)R 103.11 0.0015808 825058000.0 62164.0 72304.0 60801.0 55792.3 64988.0 60386.0 59068.0 63457.0 63372.0 56941.0 True False 61277.529960518594 72136.58453034445 55802.17647864716 59895.45185965678 61165.533611323925 57803.431546641266 62126.25201805628 66405.44388116793 56234.37802325562 66783.17598088668 0.9175593861851704 1.080161035632536 0.8355723677265323 0.8968643820832786 0.9158823717642521 0.8655388231788286 0.930268006957872 0.9943439033233931 0.8420440806731007 1.0 16.02719708425509 -4.335822706472536 0.0009212498395873679 1.8481453342816132 6.0423170855503925e-06 0.004824568311397992 0.07317220396834391 14096709.424446387 1863.9477025213193 1856291.3898833266 1883085.7122514786 4.6150593826330526e-05 4.335822706472536 -1.8481392919645276 AS(ph)PEPQR ddPTM_PC-9_AZD4547_30min_R2 1 ASPEPQR 7 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 AS(1)PEPQR 70.816 0.043012 10187000.0 30480.0 24061.0 25065.0 19895.0 16426.0 33558.0 28568.0 30291.0 43965.0 29168.0 True False 40172.00597661541 31838.247711500146 24732.62172281995 15308.515124685922 14145.533433398774 31459.61295505143 31110.496656450825 25610.221967933303 46288.9001436736 28146.837198048233 1.4272298409215594 1.1311483236101527 0.8786998535144462 0.5438804728563765 0.5025620937040719 1.117696199174837 1.105292805637434 0.9098792090824747 1.6445506760838968 1.0 14.7806851983009 -8.225704691377784 24.546075498079276 1.322275585660528 0.9376148098048268 0.19578692037947276 0.2989956533744523 684.9311050691578 470478.93307620776 0.21462009709451355 0.08111156426119036 5.946963987957063e-09 8.225704691377784 -0.38466077585570113 AS(ph)PEPQR ddPTM_PC-9_Lapatinib_30min_R1 1 ASPEPQR 7 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 AS(1)PEPQR 73.233 0.036802999999999995 12233000.0 16871.0 43220.0 21371.0 26393.0 41912.0 28995.0 44152.0 62513.0 36289.0 37281.0 True False 16630.416446237512 43119.92674542889 19613.958874445645 28334.029264467004 39446.81856216241 27754.95144064626 46437.97452260483 65417.58219492644 32201.750679888966 43724.971176190025 0.38034139300458664 0.9861624967498983 0.4485756844849842 0.6480056704964966 0.9021576801780206 0.634762029431821 1.0620470013686858 1.4961149301008323 0.7364613357921227 1.0 15.416169812661925 -7.3057569803677325 5.643254244924751 1.1199649615316172 0.6808702270118564 0.39559272328255335 0.24383657907755713 0.19785732198769296 16.10414526513425 0.09787616077517157 0.06628525781391496 4.945873674942944e-08 7.3057569803677325 -0.4390947345197608 AS(ph)PEPQRENAS(ph)PAPGTTAEEAMSR ddPTM_PC-9_AZD4547_30min_R2 2 ASPEPQRENASPAPGTTAEEAMSR 24 1 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 2 AS(1)PEPQRENAS(0.971)PAPGT(0.021)T(0.008)AEEAMSR;AS(1)PEPQRENAS(0.999)PAPGTTAEEAMSR 130.62 1.6934e-06 34735000.0 31276.0 43575.0 50097.0 46996.0 51145.0 51015.0 51223.0 64041.0 48735.0 44463.0 True False 41221.11741878682 57659.76659443167 49432.68104720171 36161.79828096205 44044.39957696213 47825.023985396925 55781.74776790045 54144.93496577916 51311.032605525594 42906.36390348393 0.9607226916620573 1.3438511528064905 1.1521060409220054 0.8428073365132153 1.0265237034776045 1.114637075585741 1.300080983170216 1.261932497649438 1.1958839653937494 1.0 15.38890402473544 -7.041859929886495 8.718143235362732 1.210984408627285 1.072857117688614 0.13712769250429413 0.14235178428010098 0.7371677749428819 145.9424468246651 0.05647455820899469 0.044164041096271284 9.081133707230368e-08 7.041859929886495 -0.13812729093867104 AS(ph)PEPQRENAS(ph)PAPGTTAEEAMSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASPEPQRENASPAPGTTAEEAMSR 24 1 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 2 AS(1)PEPQRENAS(0.984)PAPGT(0.007)T(0.007)AEEAMS(0.001)R 59.228 0.016162 3258100.0 7104.0 8361.2 7419.6 5636.3 8463.3 5170.4 9334.5 5855.9 6143.0 4294.9 True False 8306.566889604303 9191.244678754249 7596.511402989693 5320.516384131147 6804.977119307393 4899.255122030998 8450.268584072364 5702.188829838919 6232.829753585782 5073.531371590309 1.6372357400050117 1.8116069470313008 1.4972828285889854 1.0486810851163455 1.3412703343892713 0.9656499119064904 1.6655595413069475 1.1239092482543487 1.2284993029681588 1.0 12.308774552367856 -5.541761865363999 4.77843400327567 1.2183577854826297 1.713813915343343 0.5464464113298099 0.19525553320484654 0.13328170828680627 7.94123556237977 0.050948447518141385 0.09605651116496454 2.8723551351864775e-06 5.541761865363999 0.4954561298607132 AS(ph)PEPQRENAS(ph)PAPGTTAEEAMSR ddPTM_PC-9_Lapatinib_30min_R1 2 ASPEPQRENASPAPGTTAEEAMSR 24 1 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 2 AS(1)PEPQRENAS(0.62)PAPGT(0.337)T(0.043)AEEAMSR;AS(1)PEPQRENAS(0.999)PAPGTTAEEAMSR 99.25399999999999 1.3209e-05 37967000.0 33974.0 48601.0 49196.0 37827.0 50246.0 50583.0 43144.0 43992.0 50116.0 34059.0 True False 33489.52452993145 48488.46737053657 45151.29478205171 40608.92376717287 47290.629067436814 48419.68300473218 45377.78521478671 46036.028920691766 44471.40833512403 39946.05276923517 0.8383688051332001 1.2138487787679595 1.1303067925856596 1.0165941551663953 1.1838623791099114 1.2121268472869755 1.135976700299531 1.1524550169359125 1.1132866767094973 1.0 15.28576533122345 -4.751895324715798 24.960931678683533 1.1345841853277325 0.8383682061583746 0.6137581412497868 0.06895784693224932 246.53568585326505 644727.9618758549 0.016839516200547484 0.21194678098398742 1.770535648033822e-05 4.751895324715798 -0.29621597916935793 AS(ph)PEPQRENASPAPGTTAEEAMSR ddPTM_PC-9_AZD4547_30min_R2 1 ASPEPQRENASPAPGTTAEEAMSR 24 1 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 AS(0.999)PEPQRENAS(0.001)PAPGTTAEEAMSR 89.396 6.9114e-06 5769900.0 1374.5 0.0 1411.7 0.0 0.0 2975.7 0.0 1621.0 2142.5 0.0 True False 1811.562408623946 0.0 1392.9799356116055 0.0 0.0 2789.6290085924825 0.0 1370.5116968743152 2255.74817599956 0.0 0.0 AS(ph)PEPQRENASPAPGTTAEEAMSR ddPTM_PC-9_Lapatinib_30min_R1 1 ASPEPQRENASPAPGTTAEEAMSR 24 1 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 AS(0.997)PEPQRENAS(0.002)PAPGTTAEEAMSR 58.622 0.0083221 5301800.0 6525.6 6318.2 6326.1 6489.1 4261.4 4723.1 4868.1 6119.5 6382.7 4048.9 True False 6432.543747351525 6303.570596089051 5805.992477452182 6966.33006100302 4010.7528302347514 4521.104023083851 5120.146398203767 6403.834310333087 5663.813113189322 4748.746970179875 1.3545770679602815 1.3274176610530761 1.222636732155106 1.466982786143088 0.8445918166245928 0.9520625233297277 1.0782099847298927 1.3485313811298985 1.1926963362663197 1.0 12.21333117107692 -6.246349585671099 24.9991268270407 1.0813539881334695 1.3332069324584157 0.47925931017506873 0.13920985978534617 876.8614806939946 1452688.3425300503 0.045475873713684514 0.05847170347703351 5.670879437696527e-07 6.246349585671099 0.2518529443249462 AS(ph)PFEEDQNR ddPTM_PC-9_AZD4547_30min_R2 1 ASPFEEDQNR 10 0 Q8TB72-4;A0A0A0MR59;Q8TB72-3;Q8TB72;C9JW01;Q8TB72-2;A0A0C4DG68 Q8TB72-4 PUM2 Pumilio homolog 2 1 AS(1)PFEEDQNR 152.96 0.00017234 11650000.0 5583.4 12593.0 17342.0 15700.0 13346.0 17402.0 16009.0 21920.0 9963.6 12353.0 True False 7358.805058065432 16663.440980463056 17112.0337489385 12080.607562582005 11493.138268728839 16313.850189040033 17433.769986457617 18532.767671489826 10490.255554907448 11920.525229960564 0.6173222166058682 1.3978780849841952 1.435510048326546 1.0134291341642478 0.9641469689475135 1.3685512906794968 1.4625001541576614 1.5546938842015385 0.8800162201361451 1.0 13.541160183299663 -6.779382856933333 24.986448475006284 1.3009049259191456 1.1184264367001377 0.06059313527356858 0.28763802361844854 666.7487112700211 928447.2494895153 0.10191163950850704 0.0900612985002938 1.6619468973738974e-07 6.779382856933333 -0.1824784892190079 AS(ph)PFEEDQNR ddPTM_PC-9_Lapatinib_30min_R1 2 ASPFEEDQNR 10 0 Q8TB72-4;A0A0A0MR59;Q8TB72-3;Q8TB72;C9JW01;Q8TB72-2;A0A0C4DG68 Q8TB72-4 PUM2 Pumilio homolog 2 1 AS(1)PFEEDQNR;AS(1)PFEEDQNR 135.1 0.00011277 18408700.0 22278.5 29771.0 33289.0 26818.0 36016.0 39430.0 32723.0 33210.0 34498.0 29838.0 True False 21960.804504623455 29702.067078624794 30552.106919256035 28790.28518222543 33897.6096901804 37743.67081581936 34417.23682513132 34753.0578390656 30612.47195995509 34995.45854336416 0.6275329833844301 0.8487406170666365 0.8730306214275716 0.8226863250427289 0.9686288193131295 1.0785305404428345 0.9834772355528261 0.9930733668199205 0.8747555606971702 1.0 15.094880091261912 -3.9920118216493603 0.5897928023157549 0.9842071864321404 4.601750715857306e-13 0.7258867741239727 0.06324566061894121 4.866407356480776 0.6434041714096336 0.03258845061945804 4.012831726586689 0.00010185636620137267 3.9920118216493603 -0.9842071864316803 AS(ph)PGGVSTSSSDGK ddPTM_PC-9_AZD4547_30min_R2 2 ASPGGVSTSSSDGK 14 0 P54259 P54259 ATN1 Atrophin-1 1 AS(1)PGGVSTSSSDGK;AS(1)PGGVSTSSSDGK 152.88 0.00015803 22980000.0 43583.0 47139.0 45412.0 44640.0 48668.0 55798.0 53091.0 62086.0 51173.0 51702.0 True False 57441.48741728443 62375.75989661305 44809.807208326296 34348.93768112491 41911.28827082984 52308.942239286036 57815.9961491049 52492.035294348425 53877.90030824996 49891.92871686402 1.151318237129377 1.2502174500126984 0.8981374013945483 0.6884668234827047 0.8400414525699297 1.0484449806728966 1.158824636289566 1.052114773759098 1.0798921126903365 1.0 15.606518821524983 -9.242258617804762 16.756349817256776 0.9999054806292882 1.0129006212401226 7.35537783194129e-05 0.15886148993106136 0.0 0.0 0.17439747815670342 0.0422976013694963 5.724550385013733e-10 9.242258617804762 0.0129951406108344 AS(ph)PGGVSTSSSDGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASPGGVSTSSSDGK 14 0 P54259 P54259 ATN1 Atrophin-1 1 AS(1)PGGVSTSSSDGK;AS(0.998)PGGVS(0.001)T(0.001)SSSDGK 154.13 1.2605e-05 21059600.0 39586.0 59857.0 51234.0 45653.0 45697.0 31200.0 42215.0 34533.0 29901.0 27347.0 True False 46287.127940860926 65799.20737886832 52455.61286602698 43095.210419022966 36743.00088865929 29563.81707553903 38216.08958986713 33626.54534073796 30338.24555786562 32304.794621267112 1.4328253277421819 2.0368248165723033 1.623771749085631 1.3340190186707528 1.1373853732681027 0.915152608835234 1.1829850657743681 1.040915001471661 0.9391251643461351 1.0 14.979460682641466 -5.947591459218318 1.890789782931076 1.032816519165573 1.7543479214490703 0.786950906490949 0.15511809841292698 0.14021958841835694 1.0148671066143573 0.048133088621385135 0.08135203173721316 1.128258309619491e-06 5.947591459218318 0.7215314022834973 AS(ph)PGGVSTSSSDGK ddPTM_PC-9_Lapatinib_30min_R1 2 ASPGGVSTSSSDGK 14 0 P54259 P54259 ATN1 Atrophin-1 1 AS(0.997)PGGVS(0.001)TS(0.001)SS(0.001)DGK;AS(0.979)PGGVS(0.008)T(0.002)S(0.008)S(0.002)SDGK 114.21 0.00017682 19816300.0 19547.7 42782.0 55098.0 47889.0 60636.0 49676.0 54253.0 56449.0 59902.0 50780.0 True False 19268.946213390842 42682.94090751826 50568.05512443058 51410.91681302085 57069.50969496272 47551.47328041188 57061.95487803225 59071.82661720606 53155.20596397555 59557.25533990317 0.3235365045521282 0.7166707173445052 0.8490662445042216 0.863218368939438 0.9582293436669895 0.7984161293032681 0.9581024940180701 0.9918493772097676 0.8925059702736459 1.0 15.86198964927286 -4.682823850337353 1.3844033651225698 0.9200671151765201 4.344810835187856e-17 0.9055289038343054 0.058592676915432296 0.4408781179915574 0.6454947893501066 0.016959150905198547 0.6068474798759711 2.0757552722175207e-05 4.682823850337353 -0.9200671151765201 down AS(ph)PGLLPVANGNSLNK ddPTM_PC-9_AZD4547_30min_R2 2 ASPGLLPVANGNSLNK 16 0 Q14814-6;Q14814-3;Q14814-5;Q14814-4;Q14814-2;Q14814 Q14814-6 MEF2D Myocyte-specific enhancer factor 2D 1 AS(1)PGLLPVANGNSLNK;AS(1)PGLLPVANGNSLNK 132.15 7.6174e-06 18372900.0 36006.0 40168.0 55290.0 59963.0 71028.0 57530.0 57095.0 86954.0 78481.0 71994.0 True False 47455.159028674985 53151.520471947915 54556.81847415577 46139.45676911498 61166.9882325245 53932.640005486275 62176.344392329134 73517.25730413893 82629.34543786311 69473.51197326813 0.6830683764329444 0.7650616610888973 0.7852894855113705 0.6641301908973368 0.8804361042818765 0.7763050761884379 0.8949647516920293 1.058205569518736 1.1893647390340227 1.0 16.084175408769788 -7.5830165168696855 1.7697940791843638 1.108599819442207 0.756425364720739 0.810606316008788 0.07008361369912337 0.14574783318357823 0.8930765086656537 0.04525642676237956 0.02121758438603591 2.6120620118791723e-08 7.5830165168696855 -0.35217445472146813 AS(ph)PGLLPVANGNSLNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASPGLLPVANGNSLNK 16 0 Q14814-6;Q14814-3;Q14814-5;Q14814-4;Q14814-2;Q14814 Q14814-6 MEF2D Myocyte-specific enhancer factor 2D 1 AS(1)PGLLPVANGNSLNK;AS(1)PGLLPVANGNSLNK 171.56 2.3159e-05 13196600.0 36561.0 27950.0 43224.0 44888.0 55529.0 41340.0 42313.0 38517.0 34485.0 35931.0 True False 42750.05518733435 30724.691284885066 44254.62408793287 42373.07088885953 44648.49106826182 39172.05762508922 38304.80632040855 37505.96956213491 34989.27788578959 42445.00587036049 1.0071869307288017 0.7238705863000066 1.0426344202448572 0.9983052191883147 1.051913886044248 0.9228896738695758 0.9024573217730886 0.8836368093972976 0.8243438107337555 1.0 15.373307194106971 -6.994308065289921 24.99023548744476 0.8957355331407845 0.9605673439799421 0.08550084792797652 0.09532130012763207 402.77915507263833 1768374.9159117637 0.03452293829006821 0.0303592129021999 1.0131924262249093e-07 6.994308065289921 0.06483181083915768 AS(ph)PGLLPVANGNSLNK ddPTM_PC-9_Lapatinib_30min_R1 2 ASPGLLPVANGNSLNK 16 0 Q14814-6;Q14814-3;Q14814-5;Q14814-4;Q14814-2;Q14814 Q14814-6 MEF2D Myocyte-specific enhancer factor 2D 1 AS(1)PGLLPVANGNSLNK;AS(1)PGLLPVANGNSLNK 193.27 1.0708e-11 16629800.0 93213.0 55170.0 79037.0 71833.0 56011.0 46620.0 44195.0 35986.0 54558.0 51621.0 True False 91883.76552682932 55042.257254634664 72538.88295164275 77115.83844786353 52716.54310186287 44626.17127652796 46483.2008522042 37658.04093335181 48413.10351879036 60543.62106934114 1.5176456892394004 0.9091338820252307 1.1981259407752194 1.2737235911202285 0.8707200225352586 0.7370912160245126 0.7677638045297387 0.621998490810811 0.7996400390941667 1.0 15.885687343822132 -6.38994258954379 3.9685540289249936 0.7637926262939215 1.199485473963042 0.6149872210634455 0.16462844053238124 0.15703531472236124 4.262214605397933 0.050855744529339546 0.0579084477465213 4.07434133965067e-07 6.38994258954379 0.43569284766912053 AS(ph)PIKMDLAPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASPIKMDLAPSK 12 1 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 AS(0.978)PIKMDLAPS(0.022)K 94.71700000000001 0.023271 4921900.0 12265.0 16154.0 16123.0 19080.0 20094.0 13358.0 16880.0 11584.0 12877.0 11803.0 True False 14341.22225520789 17757.662361933217 16507.433466817994 18011.00945819462 16156.724945985945 12657.482964584959 15281.004199383087 11279.93227426255 13065.301764109412 13942.790467503402 1.0285761870002361 1.2736089237890489 1.1839404389883095 1.291779396683401 1.158787043643995 0.9078156194117581 1.095978902860132 0.8090154048110239 0.9370650584300781 1.0 13.767231706232616 -6.6898026990668145 5.190709186507704 0.9472260361956437 1.2016759289659544 0.6105048305309342 0.09482749966959533 0.13271525044831517 6.549102750985706 0.03119776613909027 0.030805081330802616 2.042665721413817e-07 6.6898026990668145 0.2544498927703107 AS(ph)PNGSISSAGNSSR ddPTM_PC-9_AZD4547_30min_R2 2 ASPNGSISSAGNSSR 15 0 Q9BSF8;E9PKU9;B7Z503;Q9BSF8-2 Q9BSF8 BTBD10 BTB/POZ domain-containing protein 10 1 AS(0.999)PNGSISSAGNSSR;AS(1)PNGSISSAGNSSR 102.63 0.0014424000000000001 5253300.0 3333.3 5245.700000000001 5794.299999999999 6870.8 6278.1 7560.4 5340.7 7530.6 5205.6 4539.1 True False 4393.220063052889 6941.269939745502 5717.463796071635 5286.843212801815 5406.494182894242 7087.646992829455 5816.01195369318 6366.918805972689 5480.75738855697 4380.1874905945115 1.002975345801147 1.5846969917726925 1.3053011562515602 1.2069901628992246 1.2343065666717459 1.6181149797922159 1.3277997725398252 1.4535722088710235 1.2512609107088886 1.0 12.09677690927432 -8.545573120951229 17.974013705997777 0.9999999901615019 1.3494787348631452 0.2643714824153227 0.17157574647658733 126.27448892653231 100011.64303587131 0.15918371926662672 0.04110105590759172 2.8472583748598978e-09 8.545573120951229 0.3494787447016433 AS(ph)PNGSISSAGNSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASPNGSISSAGNSSR 15 0 Q9BSF8;E9PKU9;B7Z503;Q9BSF8-2 Q9BSF8 BTBD10 BTB/POZ domain-containing protein 10 1 AS(0.999)PNGS(0.001)ISSAGNSSR 98.281 0.0022866999999999996 2874900.0 4333.6 3974.6 4070.0 4232.0 4422.3 2466.6 4024.7 3000.7 3936.2 2883.1 True False 5067.192887498482 4369.172020783693 4167.044235560953 3994.894760329121 3555.7820607461754 2337.247153798865 3643.4512796953263 2921.934804504457 3993.759478441211 3405.7832073929562 1.4878201514703264 1.28286850768995 1.223520107361949 1.1729738850251468 1.0440423961888166 0.6862583468981194 1.0697836761266726 0.857933293628847 1.1726405455790405 1.0 11.73377088891715 -5.657613669587361 1.059750258937428 0.9541257079059059 1.437464309582744 0.6219837549305581 0.1309352703754583 0.4211514335495133 0.86209203231791 0.04851075962944759 0.16570554941269575 2.1998158679014008e-06 5.657613669587361 0.48333860167683806 AS(ph)PNGSISSAGNSSR ddPTM_PC-9_Lapatinib_30min_R1 2 ASPNGSISSAGNSSR 15 0 Q9BSF8;E9PKU9;B7Z503;Q9BSF8-2 Q9BSF8 BTBD10 BTB/POZ domain-containing protein 10 1 AS(1)PNGSISSAGNSSR;AS(1)PNGSISSAGNSSR 125.41 2.651e-05 4800400.0 5117.1 7288.799999999999 5944.5 6248.799999999999 7177.9 5163.700000000001 5213.2 6066.9 6730.7 3712.6000000000004 True False 5044.12921563879 7271.923231422537 5455.766156433585 6708.357597385725 6755.710034294365 4942.860588172618 5483.113987616498 6348.790322307344 5972.617688586863 4354.3179632714555 1.158420046075154 1.6700487407582536 1.2529553887549814 1.5406218962350764 1.551496719182793 1.1351629876057518 1.259236012130121 1.4580447215520786 1.3716540084958697 1.0 12.088231045262601 -6.754946810159931 24.99856445809159 1.2743483684976598 1.4435696751156744 0.20652200688822764 0.18113118899524386 277.3931606441376 1068054.6520515843 0.05858741089804089 0.05726100459762188 1.7581389273138047e-07 6.754946810159931 0.1692213066180146 AS(ph)PNPVAMETR ddPTM_PC-9_Lapatinib_30min_R1 1 ASPNPVAMETR 11 0 H7BXF5;A0A2R8YDB8;Q9H0E3;Q9H0E3-3 H7BXF5 SAP130 Histone deacetylase complex subunit SAP130 1 AS(1)PNPVAMETR 69.92 0.033513999999999995 2135000.0 12542.0 9620.3 10432.0 8530.2 10119.0 10947.0 10055.0 10326.0 11665.0 7972.8 True False 12363.148780078887 9598.02478641947 9574.32122868452 9157.53936391302 9523.820314719436 10478.822328703385 10575.598700507142 10805.783656916332 10351.164862104357 9350.887856911775 1.322136354243686 1.0264292474992116 1.0238943483433598 0.9793229802391609 1.0184936939094866 1.1206232487279686 1.130972680063756 1.1555890544585197 1.1069713401014878 1.0 13.190887638534162 -6.795820662091826 24.970483825878425 1.1143144563461886 1.0633597683451534 0.008835145339753825 0.09700745455071663 603.2048011237185 438092.2198603947 0.03456532876782283 0.030485518622688588 1.6002186877741782e-07 6.795820662091826 -0.0509546880010352 AS(ph)PNSDEDKPEVPPR ddPTM_PC-9_Lapatinib_30min_R1 1 ASPNSDEDKPEVPPR 15 1 Q9UJM3 Q9UJM3 ERRFI1 ERBB receptor feedback inhibitor 1 1 AS(0.92)PNS(0.08)DEDKPEVPPR 91.065 0.005828 0.0 8450.8 15699.0 13903.0 13281.0 14905.0 13984.0 14593.0 15840.0 14241.0 12231.0 True False 8330.290042313076 15662.649930043694 12759.949007131987 14257.729044117226 14028.31720435747 13385.936918296167 15348.554135902607 16575.98422676299 12637.028615621775 14345.112053216926 0.5807058189165548 1.0918457710151734 0.889498036668911 0.9939085167982286 0.9779161816454118 0.9331357516509841 1.069950104186231 1.155514447379014 0.8809292369931604 1.0 13.808271616947696 -4.753696811627685 24.999967354030222 0.9999380407446894 0.5807050670007771 0.6958291573909436 0.08300406544231823 157.6560281749679 509014.1603854329 0.020424362523076053 0.2139676871694987 1.7632065413546077e-05 4.753696811627685 -0.41923297374391233 AS(ph)PPAESMSVYR ddPTM_PC-9_Lapatinib_30min_R1 1 ASPPAESMSVYR 12 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 AS(1)PPAESMSVYR 101.38 0.0027386999999999997 15090000.0 7236.0 11490.0 7808.2 9318.8 7172.3 9056.2 9833.6 4977.2 7674.0 5102.2 True False 7132.813313080114 11463.39561094349 7166.239936523622 10004.135638605498 6750.439415284343 8668.8874370333 10342.735691825666 5208.458882161917 6809.673309197498 5984.108471745844 1.1919592278044284 1.9156396754952338 1.1975451264560542 1.6717838063665351 1.128061004769007 1.44865145375685 1.7283670141775032 0.8703817630903282 1.137959537556778 1.0 12.54692061133006 -7.771072141231088 24.999344243333013 1.003127906421419 1.469527047758321 0.42754634121499246 0.24714096918631007 189.8531258467418 492706.39811250364 0.12521134780227877 0.061357789532365654 1.694056375127802e-08 7.771072141231088 0.4663991413369022 AS(ph)PPALLPGPAPR ddPTM_PC-9_AZD4547_30min_R2 2 ASPPALLPGPAPR 13 0 A6NEL2 A6NEL2 SOWAHB Ankyrin repeat domain-containing protein SOWAHB 1 AS(1)PPALLPGPAPR;AS(1)PPALLPGPAPR 97.779 0.0029253 14013500.0 24124.0 25721.0 26765.0 36444.0 31461.0 34747.0 31334.0 33389.0 30371.0 27276.0 True False 31794.930189628285 34034.8102484309 26410.078612059664 28042.398854187166 27093.18320638978 32574.26459709079 34122.665297998785 28229.497252891146 31976.34905637463 26321.07554216827 1.2079647026083908 1.2930630510863688 1.0033814374245005 1.0653971494919048 1.029334198862221 1.2375734625625179 1.2964008724997504 1.0725054607918831 1.214857235037611 1.0 14.68393082180077 -11.45529309161039 2.4282912833563275 0.8940075396739362 1.154679069773671 0.17414973418624002 0.10290457814115013 44785464.344184056 22396237.343817644 26912293.18681872 0.028754253271038498 3.5051524246261467e-12 11.45529309161039 0.26067153009973487 AS(ph)PPALLPGPAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASPPALLPGPAPR 13 0 A6NEL2 A6NEL2 SOWAHB Ankyrin repeat domain-containing protein SOWAHB 1 AS(1)PPALLPGPAPR;AS(1)PPALLPGPAPR 101.89 0.0018887 11601700.0 19165.300000000003 14089.4 17301.699999999997 20532.3 23696.0 25750.6 18256.2 22430.4 24526.0 21913.2 True False 22409.606758070597 15488.102518399279 17714.23814506263 19381.941797614738 19052.938903159284 24400.193204659477 16526.840572557918 21841.625766973295 24884.646351366573 25885.889695204256 0.8657074190585888 0.5983222018159445 0.6843202359911337 0.7487454372180814 0.7360356985021504 0.9426059328831944 0.6384497796735864 0.8437656972253799 0.9613208834764069 1.0 14.659878283871564 -8.136354353552052 2.9038926132351492 0.9881708570058018 0.7438823403948288 0.48614697676297525 0.09602098452288084 0.23233671176233942 3.509444829556382 0.08014215265776999 0.025454094487750132 7.305427690593727e-09 8.136354353552052 -0.24428851661097295 AS(ph)PPALLPGPAPR ddPTM_PC-9_Lapatinib_30min_R1 1 ASPPALLPGPAPR 13 0 A6NEL2 A6NEL2 SOWAHB Ankyrin repeat domain-containing protein SOWAHB 1 AS(1)PPALLPGPAPR 92.051 0.0048097999999999995 5724100.0 11993.0 8133.3 8705.5 14025.0 11921.0 10794.0 11190.0 12230.0 15107.0 12672.0 True False 11821.977620753154 8114.467843558464 7989.767394201793 15056.445286028471 11219.830217587752 10332.365782042962 11769.363446909498 12798.250447810058 13405.490576237504 14862.338315621379 0.7954318741572053 0.5459751804350719 0.5375848150222753 1.0130603251174193 0.7549168898809758 0.6952045877722288 0.7918917734862122 0.8611195745933319 0.9019772186283349 1.0 13.859373494817604 -7.29933264499541 0.200873539635317 1.0670911108635641 0.5433026175285736 0.36807498499091373 0.12441809916740666 4.31403075299281 0.6333370892638042 0.5089873550347617 0.8250139152403733 5.019579708444149e-08 7.29933264499541 -0.5237884933349906 AS(ph)PPDPK ddPTM_PC-9_Lapatinib_30min_R1 1 ASPPDPK 7 0 Q5T670;Q7L590-2;Q7L590 Q5T670 MCM10 Protein MCM10 homolog 1 AS(1)PPDPK 74.301 0.034381999999999996 2033500.0 39854.0 56929.0 54264.0 41472.0 51006.0 48217.0 44476.0 46735.0 41198.0 40559.0 True False 39285.67465167149 56797.18439820734 49802.6233850975 44521.98922653639 48005.92736165427 46154.87130931677 46778.74965726066 48906.47871450554 36557.847405827255 47569.56910852961 0.8258572736288934 1.1939814772890835 1.0469429157845258 0.9359342550477976 1.0091730545662314 0.9702604453703328 0.9833755178764663 1.028104303466062 0.7685133183027326 1.0 15.537751336785849 -8.226361088587376 24.98266625400775 0.884256475529315 1.0040185232131538 0.1686848874687742 0.1016222500572938 838.4179719032368 597120.6904715385 0.06518583986609894 0.024636055464421 5.937982473646435e-09 8.226361088587376 0.1197620476838388 AS(ph)PPGDLQNPK ddPTM_PC-9_AZD4547_30min_R2 3 ASPPGDLQNPK 11 0 O00273 O00273 DFFA DNA fragmentation factor subunit alpha 1 AS(1)PPGDLQNPK;AS(1)PPGDLQNPK;AS(1)PPGDLQNPK 132.14 0.00012319999999999999 96516000.0 203563.0 233288.0 146827.0 120322.0 140961.0 200473.0 231370.0 228431.0 200917.0 157132.0 True False 268291.7996265666 308693.78380451555 144879.97804494263 92583.62185636896 121390.99831397296 187937.39161863123 251961.48177691846 193132.23777217613 211537.06243981514 151630.85650725858 1.7693746893378752 2.0358243098741475 0.9554782013514987 0.610585628736701 0.8005692318183402 1.2394402824575133 1.6616768353139062 1.273700104456845 1.3950792557165885 1.0 17.210203842722805 -7.02506593714978 24.44961321924939 1.3690132484407913 1.2078696640213427 0.007628392893729852 0.426465342742018 3049.1136297090825 2974132.2377298726 0.18431140899824328 0.1434909822477658 9.43917554275738e-08 7.02506593714978 -0.16114358441944865 AS(ph)PPGDLQNPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ASPPGDLQNPK 11 0 O00273 O00273 DFFA DNA fragmentation factor subunit alpha 1 AS(1)PPGDLQNPK;AS(1)PPGDLQNPK;AS(1)PPGDLQNPK;AS(1)PPGDLQNPK 136.38 8.0862e-05 100636100.0 118644.0 184180.0 145079.0 119535.0 154599.0 90974.0 133916.0 85328.0 86565.0 90605.0 True False 138728.08587418543 202464.17319678492 148538.2335751716 112837.84148769878 124306.4357482073 86203.16328942588 121230.50701212 83088.23041248902 87830.84936010938 107030.96927121481 1.296149019473519 1.8916410322674353 1.387806114310504 1.0542541308933626 1.1614062415263822 0.8054039300624141 1.1326675618990591 0.7763008312289945 0.8206115478366581 1.0 16.707668773394467 -5.737981405707182 2.1816369229320927 0.9447154226220489 1.6086537830232555 0.6744974263474386 0.1825615344172683 0.16613738377716403 1.6112505415248417 0.05316754173843086 0.10380504598521152 1.8281784878220617e-06 5.737981405707182 0.6639383604012066 AS(ph)PPGDLQNPK ddPTM_PC-9_Lapatinib_30min_R1 2 ASPPGDLQNPK 11 0 O00273 O00273 DFFA DNA fragmentation factor subunit alpha 1 AS(1)PPGDLQNPK;AS(1)PPGDLQNPK 116.71 0.0012337 79197000.0 68380.0 124737.0 98905.0 106934.0 146284.0 110650.0 121212.0 126389.0 93949.0 107699.0 True False 67404.88866064377 124448.17914031839 90773.41268434067 114798.28308136684 137679.86272540956 105917.75743774814 127487.76426512895 132261.49434572918 83367.47429317111 126314.62865010275 0.533626939183413 0.985223805589814 0.7186294545169993 0.9088280930577193 1.089975596625384 0.8385232856215342 1.009287408968884 1.0470797860800392 0.6599985701110106 1.0 16.946662203497603 -4.755325053000405 24.97794427173301 0.9182800582805632 0.5336263011681881 0.426225473639274 0.1336154530035969 193.76862930160664 791496.5123340158 0.03228300332423846 0.2898040335453081 1.756608366862934e-05 4.755325053000405 -0.38465375711237515 AS(ph)PPLFQSR ddPTM_PC-9_AZD4547_30min_R2 4 ASPPLFQSR 9 0 O15055 O15055 PER2 Period circadian protein homolog 2 1 AS(1)PPLFQSR;AS(1)PPLFQSR;AS(1)PPLFQSR;AS(0.996)PPLFQS(0.004)R 107.55 0.0024945999999999996 45468100.0 107216.0 114434.7 113098.8 128183.0 117530.3 136838.0 128825.4 141293.1 127137.0 126801.7 True False 141308.45776866144 151423.4788824739 111599.0360145569 98632.38975760814 101213.24656565113 128281.49822824127 140290.61103213168 119459.49798743523 133857.20226467028 122362.41107843354 1.1548355129916785 1.237499960550895 0.9120369158386608 0.8060677203752171 0.8271596291182435 1.048373410573069 1.1465172171395535 0.9762761041939787 1.093940541747487 1.0 16.90080091417218 -5.25842557075713 24.988391254287748 0.9726967376176612 1.1961677526272916 0.4182517077110598 0.10365397718151609 270.0209713048929 2238797.417064177 0.03020550858445617 0.07298834360025717 5.515367164603821e-06 5.25842557075713 0.2234710150096304 AS(ph)PPLFQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASPPLFQSR 9 0 O15055 O15055 PER2 Period circadian protein homolog 2 1 AS(1)PPLFQSR 84.31 0.013306 7639900.0 20639.0 24749.0 22888.0 25130.0 19821.0 17798.0 18181.0 17941.0 15592.0 15112.0 True False 24132.77506116881 27205.917159557095 23433.736723223356 23722.04757255927 15937.217336239046 16864.641548411673 16458.764060958758 17470.067760060807 15820.003502834026 17851.685973473814 1.3518485087082641 1.5239970723203917 1.3126903956323244 1.3288407385055028 0.8927569844058698 0.9447086159520838 0.9219725288365017 0.9786228475013474 0.8861910032666547 1.0 14.123772713227167 -6.190147320564034 4.010953195700864 0.934951000066729 1.3967042634123288 0.9255722011772646 0.061489658430419515 0.05616164884161381 1.7609454923217878 0.018685518364217255 0.02426606339748055 6.454352485546378e-07 6.190147320564034 0.46175326334559974 AS(ph)PPLFQSR ddPTM_PC-9_Lapatinib_30min_R1 2 ASPPLFQSR 9 0 O15055 O15055 PER2 Period circadian protein homolog 2 1 AS(1)PPLFQSR;AS(1)PPLFQSR 121.36 0.0016214000000000003 11845500.0 22728.7 23760.8 29119.0 24061.9 28862.8 23972.3 25611.0 29311.7 30487.0 25373.8 True False 22404.58457006689 23705.783327459194 26724.948222590545 25831.492394145353 27165.14685044811 22947.06061116069 26937.01226441456 30673.628589621774 27053.23301765756 29759.627521536753 0.7528516462060189 0.796575269979557 0.8980269730610694 0.8680045600520824 0.9128187787561842 0.7710802359523528 0.905152870106338 1.0307127858849567 0.9090581862316455 1.0 14.861068848999604 -1.522878745341925 0.13558623304411543 1.0403723446549393 0.11919115616421617 0.5503444914633304 0.05804584553194392 64.7293973686021 0.5909345198715011 0.2932463056210512 11.479492336784846 0.02999999999574569 1.522878745341925 -0.9211811884907232 AS(ph)PPPQGPLPGPPGALHR ddPTM_PC-9_AZD4547_30min_R2 3 ASPPPQGPLPGPPGALHR 18 0 A0A087WXV6;Q96G74-2;Q96G74-3;Q96G74-5;Q96G74 A0A087WXV6 OTUD5 OTU domain-containing protein 5 1 AS(1)PPPQGPLPGPPGALHR;AS(1)PPPQGPLPGPPGALHR;AS(1)PPPQGPLPGPPGALHR 124.46 4.4905e-05 31629100.0 23520.7 24552.4 32961.9 42843.3 39490.5 32766.64 28985.16 35395.8 25711.3 35311.3 True False 30999.793339047832 32488.483151649438 32524.80366907714 32966.43910738659 34007.92573064862 30717.73682095197 31564.783088304794 29926.192424567504 27070.346827340712 34075.062134923224 0.909750163222048 0.9534387060838925 0.9545046034044575 0.9674652676157437 0.9980297496154585 0.9014726576087337 0.926330903325172 0.8782432239175998 0.7944327942867214 1.0 15.056428667296409 -7.239659629459344 1.8240787957505329 0.8825234428446875 0.9552458964139896 0.18675621581649537 0.05285305855129708 0.49533706783666365 3.219698217187994 0.026865631956002736 0.017047519519058748 5.758911048808219e-08 7.239659629459344 0.07272245356930207 AS(ph)PPPQGPLPGPPGALHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 ASPPPQGPLPGPPGALHR 18 0 A0A087WXV6;Q96G74-2;Q96G74-3;Q96G74-5;Q96G74 A0A087WXV6 OTUD5 OTU domain-containing protein 5 1 AS(1)PPPQGPLPGPPGALHR;AS(1)PPPQGPLPGPPGALHR;AS(1)PPPQGPLPGPPGALHR;AS(1)PPPQGPLPGPPGALHR;AS(1)PPPQGPLPGPPGALHR;AS(1)PPPQGPLPGPPGALHR 109.1 0.0012783 29224300.0 123707.6 136966.4 124944.9 148862.9 161346.8 151059.3 192812.0 187482.4 164859.1 151007.9 True False 144648.8533435265 150563.51901259672 127924.06027217188 140522.59433303363 129732.05277769483 143137.48438330053 174547.45152200514 182561.18565402264 167269.85245472426 178384.43689212092 0.810882697300571 0.844039545353673 0.7171256781191889 0.7877514248511238 0.7272610494386967 0.8024101590760622 0.9784903580325439 1.023414311442582 0.9376930822495558 1.0 17.444630227598758 -7.243002863383816 4.361875385009777 0.9888866892282685 0.7774623380982146 0.8628809599260585 0.03980160776925071 0.07213416936720181 3.4594651138456753 0.016617393253281074 0.012005299200853685 5.714748688199761e-08 7.243002863383816 -0.21142435113005387 AS(ph)PPPQGPLPGPPGALHR ddPTM_PC-9_Lapatinib_30min_R1 3 ASPPPQGPLPGPPGALHR 18 0 A0A087WXV6;Q96G74-2;Q96G74-3;Q96G74-5;Q96G74 A0A087WXV6 OTUD5 OTU domain-containing protein 5 1 AS(1)PPPQGPLPGPPGALHR;AS(1)PPPQGPLPGPPGALHR;AS(1)PPPQGPLPGPPGALHR 117.23 6.354699999999999e-05 103473000.0 89149.0 80889.0 94646.0 82358.0 83443.0 85982.0 76490.0 87964.0 106232.0 65703.0 True False 87877.71891207578 80701.70649030544 86864.5712241255 88414.88205823429 78535.04679524995 82304.75029383152 80450.27793155552 92051.12856836972 94267.03348744706 77059.67600625561 1.1403852632983036 1.0472624681649865 1.1272376906577435 1.147356005637201 1.0191458213355915 1.0680650965512768 1.043999690902213 1.1945434154290646 1.223299115347884 1.0 16.23368849981695 -7.7625693203352135 24.999175408175912 1.156690946892593 1.0842085848653187 0.10200160069153774 0.06847772529789901 50.53897136179012 1118038.0111683481 0.033882099266179404 0.017734210153735767 1.727550213896086e-08 7.7625693203352135 -0.07248236202727432 AS(ph)PSKPASAPASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASPSKPASAPASR 13 1 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 AS(0.763)PS(0.236)KPAS(0.001)APASR 52.599 0.043275 258580000.0 27219.0 25155.0 28569.0 33352.0 30014.0 28177.0 26149.0 22284.0 24540.0 25462.0 True False 31826.639100244887 27652.22215639657 29250.19330853585 31483.395568642907 24132.97215730179 26699.348517226397 23671.977417634396 21699.068611849685 24898.851074881164 30078.059042918914 1.0581347371793803 0.9193486227598371 0.97247609185148 1.046722979156291 0.8023447298532802 0.8876685985331908 0.7870181178864113 0.7214251618060494 0.8278077730797906 1.0 14.876423851501729 -6.26853370628243 24.97055928541841 0.8237452455560221 0.9915622873480516 0.5027376539528139 0.07778071562077225 434.3663536422341 1528876.722997988 0.023520623234106513 0.02722228584668394 5.388480229020507e-07 6.26853370628243 0.1678170417920295 AS(ph)PSKPASAPASR ddPTM_PC-9_Lapatinib_30min_R1 1 ASPSKPASAPASR 13 1 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 AS(0.965)PS(0.035)KPASAPASR 144.88 0.00045591 115770000.0 58127.0 36882.0 55106.0 39803.0 40929.0 43522.0 32804.0 39894.0 50713.0 28387.0 True False 57298.098320813726 36796.601995023346 50575.397395311484 42730.24539891561 38521.636689510044 41660.66551473722 34502.43060879528 41747.62088020726 45001.16790843531 33293.6551267001 1.7209915253451125 1.1052136467141462 1.5190701412279652 1.2834350940533341 1.1570263626181834 1.2513094568979042 1.0363064817454 1.2539212267723479 1.3516439615050342 1.0 15.022959644250932 -4.752366559791404 24.998221822789436 1.2304639950046297 1.7209924731596906 0.5147050584666695 0.14617127353462567 299.36082569630656 824765.2812617547 0.03587813650020069 0.43037753137782264 1.7686155545369085e-05 4.752366559791404 0.49052847815506095 AS(ph)PSPQPSSQPLQIHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASPSPQPSSQPLQIHR 16 0 B5MBZ0;Q9HC35 B5MBZ0 EML4 Echinoderm microtubule-associated protein-like 4 1 AS(0.944)PS(0.028)PQPS(0.014)S(0.014)QPLQIHR;AS(0.96)PS(0.04)PQPSSQPLQIHR 134.02 3.9192000000000005e-06 36940000.0 14676.7 13267.3 15014.6 15796.4 19844.6 17826.1 13651.9 14802.2 14985.599999999999 13865.400000000001 True False 17161.175431961645 14584.389863468905 15372.605007187596 14911.378920619783 15956.193085653053 16891.267934944437 12358.693200803204 14413.657934227303 15204.736050030126 16379.087261553992 1.0477491912655852 0.8904275086013058 0.9385507728059503 0.9103913229414617 0.9741808460295841 1.0312704038516645 0.7545410194994377 0.8800037330565992 0.9283017916217849 1.0 13.999567343370924 -7.232144750843111 24.98636354564418 0.8807118483846476 0.9586936508225707 0.19288532996842522 0.07297349413333579 1112.9591779227076 949281.1407626753 0.027447339818325166 0.021256882063977498 5.8594283655270534e-08 7.232144750843111 0.07798180243792319 AS(ph)PSTAGETPSGVK ddPTM_PC-9_AZD4547_30min_R2 2 ASPSTAGETPSGVK 14 0 A0A087WW69;F8W8L6;A0A087WTA5;E7ERK9;Q9UI10-3;Q9UI10;Q9UI10-2 A0A087WW69 EIF2B4 Translation initiation factor eIF-2B subunit delta 1 AS(0.694)PS(0.252)T(0.054)AGET(0.001)PSGVK;AS(0.653)PS(0.328)T(0.018)AGETPSGVK 80.737 0.011245 17369800.0 53935.0 58904.0 64471.0 54987.0 60771.0 69955.0 67991.0 83273.0 59941.0 63873.0 True False 71085.20808230809 77943.56606949861 63616.07241539692 42310.596690681334 52333.99563381687 65580.70279130536 74042.06728398032 70405.07127317377 63109.35888802314 61636.82571142809 1.1532911901582266 1.264561650764035 1.0321114314555278 0.6864499623775486 0.8490702600233616 1.0639857266229404 1.2012634724349889 1.1422566048874245 1.023890477155478 1.0 15.911504944706794 -5.342496185891348 6.031440392935462 0.9965017506772607 1.2077924488027367 0.26735862417391676 0.13898115296595664 0.32189210949669794 18.911741118291733 0.042365721185036655 0.09015112861449384 4.544685284753596e-06 5.342496185891348 0.21129069812547607 AS(ph)PSTAGETPSGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASPSTAGETPSGVK 14 0 A0A087WW69;F8W8L6;A0A087WTA5;E7ERK9;Q9UI10-3;Q9UI10;Q9UI10-2 A0A087WW69 EIF2B4 Translation initiation factor eIF-2B subunit delta 1 AS(0.818)PS(0.077)T(0.101)AGET(0.004)PS(0.001)GVK;AS(0.988)PS(0.01)T(0.001)AGETPSGVK 143.58 0.00016723 10135800.0 32767.0 59841.0 40403.0 36095.0 46305.0 31657.0 36578.0 25549.2 29466.2 23336.8 True False 38313.80592225007 65781.61900460864 41366.36074923074 34072.714171568885 37231.86765322378 29996.85119103651 33113.067038212954 24878.560571615053 29897.087430426403 27567.57710599284 1.3898140476741836 2.3861951578729257 1.5005439393597713 1.235970576614871 1.3505672809065996 1.0881206961244183 1.2011598593122133 0.9024572771107537 1.0845018158642297 1.0 14.750684855066847 -5.60784679485858 3.037671119180826 1.1256205778029424 1.9013853575307798 0.5884404592436984 0.25516101936134844 0.15640383936761415 2.8844872155565224 0.06863837590371809 0.13507172453396882 2.4669094301519083e-06 5.60784679485858 0.7757647797278373 AS(ph)PSTAGETPSGVK ddPTM_PC-9_Lapatinib_30min_R1 1 ASPSTAGETPSGVK 14 0 A0A087WW69;F8W8L6;A0A087WTA5;E7ERK9;Q9UI10-3;Q9UI10;Q9UI10-2 A0A087WW69 EIF2B4 Translation initiation factor eIF-2B subunit delta 1 AS(0.659)PS(0.302)T(0.038)AGET(0.001)PSGVK 77.288 0.015304 8253400.0 11820.0 20059.0 27242.0 22102.0 31080.0 34878.0 30204.0 29447.0 28237.0 29989.0 True False 11651.444632477474 20012.554617921283 25002.26791716102 23727.45481011063 29251.93550563102 33386.34924458906 31767.81533069298 30815.215121558693 25056.651711207945 35172.558692169274 0.33126519837385393 0.5689820519761284 0.7108458652661929 0.6746013282051398 0.8316692499298777 0.9492158229597925 0.9031988718456723 0.87611525198533 0.7123920648055239 1.0 15.102162669822059 -4.742501117016854 0.6568186412108405 0.8845798608050721 4.094713114381665e-16 0.8216897634629169 0.08063336299681749 1.456294851095576 0.4586441664708137 0.038287649198997756 0.9823056510090479 1.809251256805919e-05 4.742501117016854 -0.8845798608050717 down AS(ph)PSVTCK ddPTM_PC-9_AZD4547_30min_R2 1 ASPSVTCK 8 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 AS(0.999)PSVT(0.001)CK 94.40899999999999 0.0067423000000000005 8310000.0 22564.0 24094.0 30280.0 36907.0 35929.0 24800.0 22528.0 33430.0 28547.0 30973.0 True False 29738.88263964402 31881.914316150003 29878.467415399475 28398.661357465866 30940.878529683687 23249.252079542162 24532.94835748122 28264.161644977426 30055.936140144437 29888.644697447475 0.9949893325937176 1.0666898629522923 0.9996594933577276 0.9501488490005419 1.0352051370307225 0.7778623726464143 0.8208116696430989 0.9456488218547835 1.0055971571943256 1.0 14.867309858947454 -6.710784096714099 24.99990654393479 0.9010125729608339 1.0086987980141695 0.3178679790056518 0.07217369197423312 128.73494137386047 63534.013995646696 0.025142352535824905 0.02514231911106453 1.946327429976326e-07 6.710784096714099 0.10768622505333558 AS(ph)PSVTCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASPSVTCK 8 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 AS(0.996)PS(0.004)VTCK 87.258 0.011859999999999999 7184700.0 43708.0 34851.0 31029.0 45721.0 55550.0 34391.0 44463.0 24408.0 33371.0 26088.0 True False 51106.90112764989 38310.776957764945 31768.84903813779 43159.40059948196 44665.3762690116 32587.475418104605 40251.14275575655 23767.315862413696 33858.987743270554 30817.547887505614 1.6583701375011153 1.2431481277359293 1.030868813901247 1.4004813347586331 1.449348807116491 1.0574324581910222 1.3061111449452993 0.7712267033435746 1.0986918189230115 1.0 14.911464452587262 -7.384659386019528 1.4795721232707115 0.96383059705023 1.3232132904557667 0.37553777658208753 0.19494944938183573 0.4603771146604779 1.9478811829295217 0.12365162857345638 0.06600629188463882 4.124208509393139e-08 7.384659386019528 0.35938269340553675 AS(ph)PSVTCK ddPTM_PC-9_Lapatinib_30min_R1 2 ASPSVTCK 8 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 AS(0.995)PS(0.002)VT(0.003)CK;AS(0.977)PS(0.02)VT(0.003)CK 81.33800000000001 0.018025 20034100.0 65794.0 85970.0 102084.0 74088.0 77736.0 88220.0 74461.0 75480.0 83724.0 66146.0 True False 64855.76549485806 85770.94174698099 93691.0475756354 79536.67867032286 73163.72131485632 84447.03625086434 78316.22623952881 78987.07635328718 74294.12146719465 77579.247965995 0.8359937379553618 1.105591301743175 1.2076818225500539 1.0252313699300855 0.9430836626171715 1.0885261002772246 1.0094996831350678 1.0181469713126023 0.9576545714874639 1.0 16.243383170358342 -7.847288511525878 1.930965226760697 0.9812336611158581 1.04084065227764 0.03879266947973026 0.09375178511956814 1.2065955780508002 8.576850829866633 0.0746138783557348 0.02816976314356625 1.4213842161211839e-08 7.847288511525878 0.05960699116178203 AS(ph)PTLDFTER ddPTM_PC-9_AZD4547_30min_R2 2 ASPTLDFTER 10 0 A0A0D9SGJ6;J3KQV8;O43426 A0A0D9SGJ6 SYNJ1 Synaptojanin-1 1 AS(0.926)PT(0.074)LDFTER;AS(0.796)PT(0.061)LDFT(0.143)ER 80.245 0.01792 15289300.0 26215.0 32397.0 43049.0 34262.0 37869.0 39732.0 39349.0 44647.0 29772.0 33445.0 True False 34550.824694126386 42868.69669213542 42478.14213228307 26363.42524262324 32611.54301652123 37247.55175904715 42850.9847708864 37747.83203599482 31345.68713925738 32274.10072986573 1.0705433741846702 1.3282692847415476 1.3161681091543087 0.8168601028820337 1.010455513214137 1.154100375121501 1.3277204880021045 1.1696013578176578 0.9712334791795076 1.0 14.978089277076101 -14.522878745228821 0.1192702478428126 0.5590623551968482 1.2022342480387753 0.07067699388831883 0.1588071818857143 526.656238240574 4.0648284224745606 56.0465837450209 1.7097964289786312 3.000000000355862e-15 14.522878745228821 0.6431718928419271 AS(ph)PTLDFTER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASPTLDFTER 10 0 A0A0D9SGJ6;J3KQV8;O43426 A0A0D9SGJ6 SYNJ1 Synaptojanin-1 1 AS(0.652)PT(0.336)LDFT(0.011)ER 70.808 0.03481 2034800.0 7667.5 7550.8 6930.5 6590.5 10941.0 7626.9 8018.3 7807.1 9082.0 6414.9 True False 8965.456309971987 8300.393522501266 7095.7494040676165 6221.255651689288 8797.18959062567 7226.931937609892 7258.7485765351585 7602.17189730621 9214.807068544047 7577.87058967954 1.1831102423657418 1.0953464333114564 0.9363777488799381 0.8209767609600177 1.1609052287864017 0.953689014886636 0.9578876401532905 1.0032068781512007 1.216015364671691 1.0 12.887576787240071 -11.127623017913637 7.0365891547912 0.9999556668593887 1.0267922247535588 0.0025104454209127214 0.12004568667910606 8.493319962398758e-05 4.7708689631590335e-06 0.11823402669810909 0.02862860119201073 7.453787067352512e-12 11.127623017913637 0.026836557894170054 AS(ph)PTLDFTER ddPTM_PC-9_Lapatinib_30min_R1 1 ASPTLDFTER 10 0 A0A0D9SGJ6;J3KQV8;O43426 A0A0D9SGJ6 SYNJ1 Synaptojanin-1 1 AS(0.896)PT(0.098)LDFT(0.007)ER 68.132 0.041786000000000004 7677600.0 10728.0 14644.0 11897.0 14323.0 17221.0 17862.0 18007.0 17890.0 18281.0 13496.0 True False 10575.016752725749 14610.09271772468 10918.874583748062 15376.361200127343 16208.094637788672 17098.083898355693 18939.314351072324 18721.234710655914 16222.001272535756 15828.765617710396 0.6680885299668369 0.9230089743307479 0.6898121336468092 0.9714188441152436 1.0239645357850176 1.0801906043276734 1.1965124008079073 1.1827349752218965 1.0248431030140075 1.0 13.95026113302556 -6.100516080596826 1.6528387003650944 1.1116288697368615 0.7713007047769701 0.709289935845167 0.09134607085743197 0.19347106549269427 1.0548980739076668 0.030511059268408514 0.046914242844069295 7.933848796169071e-07 6.100516080596826 -0.3403281649598914 AS(ph)PTSTEEEQVMLR ddPTM_PC-9_AZD4547_30min_R2 1 ASPTSTEEEQVMLR 14 0 Q96PE3-2;Q96PE3-4;Q96PE3-3;Q96PE3 Q96PE3-2 INPP4A Type I inositol 3,4-bisphosphate 4-phosphatase 1 AS(0.853)PT(0.118)S(0.025)T(0.004)EEEQVMLR 123.68 3.5645e-05 3974300.0 10672.0 11028.0 17241.0 17168.0 16457.0 12808.0 16434.0 18747.0 12343.0 16112.0 True False 14065.474008610216 14592.585335706079 17012.37307493072 13210.18284295592 14172.229618497722 12007.113735273222 17896.59416312351 15850.081913203452 12995.425781266084 15547.923784111113 0.9046528786682208 0.9385552398075604 1.0941893793122508 0.8496428864962535 0.9115191079712357 0.772264766794371 1.1510600651009477 1.0194339857390555 0.8358302987403692 1.0 13.92443432026855 -7.260761695159357 24.999995732622647 1.0032005765645964 0.9184717965380882 0.15030922039007533 0.10381823076366942 139.92330636202473 5161939.330369239 0.042482062168901595 0.03101758767659199 5.4857789646302586e-08 7.260761695159357 -0.08472878002650819 AS(ph)PVAALK ddPTM_PC-9_AZD4547_30min_R2 2 ASPVAALK 8 0 H9KVB4;O15417;O15417-2 H9KVB4 TNRC18 Trinucleotide repeat-containing gene 18 protein 1 AS(1)PVAALK;AS(1)PVAALK 92.051 0.0082649 15447200.0 100701.0 113902.0 132839.0 97204.0 116356.0 131150.0 118865.0 150970.0 133681.0 114249.0 True False 132721.82328907968 150718.59402499016 131077.4680645394 74795.1195868293 100201.97785075751 122949.16976741758 129443.75472798305 127641.0554454752 140747.10474482938 110249.17728468927 1.2038350449215667 1.3670722787871636 1.1889201470054203 0.6784188456453578 0.9088682593250784 1.115193535185609 1.174101774870654 1.1577506389537584 1.2766272566496102 1.0 16.75040836439895 -5.53021988825247 24.997828159775096 1.0444667053252015 1.2835893835657455 0.2762652992585841 0.16007020874361277 231.28787775382932 787571.3841954137 0.04797898984380774 0.08332427912977182 2.949715373964203e-06 5.53021988825247 0.239122678240544 AS(ph)PVAALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASPVAALK 8 0 H9KVB4;O15417;O15417-2 H9KVB4 TNRC18 Trinucleotide repeat-containing gene 18 protein 1 AS(1)PVAALK;AS(1)PVAALK 91.265 0.0088545 9795400.0 83155.0 104248.0 102776.0 90101.0 114783.0 81872.0 88808.0 62614.0 70780.0 71377.0 True False 97231.49911388604 114597.05248896944 105226.5696201504 85052.9330813833 92292.09512665968 77578.48819258115 80395.46332575892 60970.44884501688 71815.02359739575 84317.0850799791 1.1531648540940067 1.3591201875665915 1.2479863306509895 1.0087271518068517 1.0945835596559805 0.9200802911888375 0.9534895952522514 0.7231090684311877 0.8517256440883304 1.0 16.363537372077836 -6.2866651838681 0.8796379657986438 0.8537944674921335 1.2804352484653578 0.7074883571989601 0.09681202019852216 0.3134098749180332 0.5213878134659087 0.049374185891391864 0.07863863582868436 5.16814650174283e-07 6.2866651838681 0.42664078097322433 AS(ph)PVAALK ddPTM_PC-9_Lapatinib_30min_R1 2 ASPVAALK 8 0 H9KVB4;O15417;O15417-2 H9KVB4 TNRC18 Trinucleotide repeat-containing gene 18 protein 1 AS(1)PVAALK;AS(1)PVAALK 91.265 0.0088545 22386000.0 144326.0 169906.0 154252.0 117281.0 175648.0 168085.0 162608.0 140697.0 155809.0 122829.0 True False 142267.88477385303 169512.5930959932 141569.99598993926 125906.23597794701 165316.72997725458 160896.39637527257 171027.0465929454 147234.29625965105 138260.14967849254 144059.82899064515 0.987561111037356 1.1766818986506007 0.9827166739114512 0.8739857381485786 1.1475560615026816 1.1168720489437811 1.1871945690290346 1.0220357561941298 0.9597411759212262 1.0 17.13630857125741 -4.493038502275661 18.193775870389512 1.0557341211894369 0.749619157896367 0.03605247031983572 0.09792847858772552 10273645.708881645 169103398.6306786 0.025554410097466715 99645941.85097809 3.2133756449460896e-05 4.493038502275661 -0.30611496329306986 AS(ph)PVAVGSSGAGADPSFQPVLSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASPVAVGSSGAGADPSFQPVLSAR 24 0 Q5TGY3 Q5TGY3 AHDC1 AT-hook DNA-binding motif-containing protein 1 1 AS(1)PVAVGSSGAGADPSFQPVLSAR 125.77 2.4739e-08 0.0 3264.9 4016.5 4952.5 4153.2 3783.0 4021.7 4251.0 1972.6 2847.1 2193.7 True False 3817.58308528563 4415.231575876239 5070.586382460844 3920.5096688560743 3041.7483064927233 3810.7949722017743 3848.314505425206 1920.8213401424634 2888.73345131598 2591.4004446803556 1.4731737401382294 1.7038013499379674 1.9566973498325118 1.5128922575066015 1.1737855153713679 1.4705542634387518 1.485032741012703 0.7412290694344591 1.1147383482340567 1.0 11.339516254605101 -7.0812277762716285 0.6708183129492641 0.9382025144495556 1.7009530193157467 0.5832112944701615 0.2185012545328323 0.54146700909835 0.5042863947752197 0.1917353941383386 0.14922198237017184 8.29415646272436e-08 7.0812277762716285 0.7627505048661911 AS(ph)PVGDGNFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASPVGDGNFR 10 0 Q86YS7-3;Q86YS7;Q86YS7-2;Q86YS7-4;Q86YS7-5;H0YFC4 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 AS(1)PVGDGNFR 80.87100000000001 0.017062 7280200.0 20223.0 27273.0 23788.0 24983.0 22593.0 22041.0 19582.0 19370.0 24118.0 16858.0 True False 23646.35447754335 29980.483199022212 24355.19613649237 23583.28350597883 18166.06383520753 20885.131159037064 17727.051198597146 18861.558024211467 24470.680123226743 19914.221952145424 1.1874104112310475 1.5054810211047345 1.223005156566938 1.1842432791323854 0.9122155954102158 1.0487545639103937 0.890170413948176 0.9471400926200608 1.2288042275530848 1.0 14.281511494315128 -5.892583237801206 2.153373486320378 0.9992471732117679 1.3408545559593945 0.5678466572122007 0.11842731250040266 0.20579908775321892 1.9408914522844596 0.03551934695437469 0.060638552070108105 1.280609626657349e-06 5.892583237801206 0.3416073827476266 AS(ph)PVGDGNFR ddPTM_PC-9_Lapatinib_30min_R1 1 ASPVGDGNFR 10 0 Q86YS7-3;Q86YS7;Q86YS7-2;Q86YS7-4;Q86YS7-5;H0YFC4 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 AS(1)PVGDGNFR 105.36 0.0024718000000000006 6094300.0 18662.0 34473.0 23284.0 21120.0 31257.0 28135.0 33413.0 23915.0 26298.0 24363.0 True False 18395.876457808332 34393.179886514816 21369.679398839184 22673.235254254654 29418.524713626415 26931.731635888344 35142.961648935365 25026.1782059998 23336.042309783123 28574.11208834307 0.6437952087866627 1.2036482456630966 0.7478685368339769 0.7934887069860798 1.029551666301044 0.9425220826678026 1.2298881428155413 0.8758339761748655 0.8166847752831193 1.0 14.802421048395269 -6.270153966144319 24.451035201246007 0.9865843070949831 0.865565632995567 0.12885258851977022 0.1693592549986271 1149.7227085979985 3225838.7468076074 0.0520471951511967 0.05993995652574033 5.368414415222366e-07 6.270153966144319 -0.12101867409941613 AS(ph)PVPAPSSGLHAAVR ddPTM_PC-9_AZD4547_30min_R2 2 ASPVPAPSSGLHAAVR 16 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 AS(1)PVPAPSSGLHAAVR;AS(1)PVPAPSSGLHAAVR 127.07 2.5889000000000002e-05 6788500.0 3755.0 3602.2 13616.699999999999 14080.5 11868.5 15018.4 10414.8 19192.7 13712.3 15010.8 True False 4949.01189114799 4766.540705139684 13436.133661006279 10834.458266556428 10220.76364022241 14079.297073846605 11341.697023858993 16226.909219370562 14437.104183784732 14485.276460931931 0.34165809016458276 0.3290610792272736 0.927571779333637 0.7479635128661796 0.705596725598487 0.9719729624643141 0.7829810535165518 1.1202346923191953 0.996674397117851 1.0 13.822299599194654 -5.004411699443465 0.5969422963653462 0.9781458574721736 1.0966686015672646e-32 0.7267997632505947 0.13532092733135145 1.630297723667591 0.5298234636363832 0.07404269003010767 1.059811886721735 9.898931080264755e-06 5.004411699443465 -0.9781458574721736 down AS(ph)PVPAPSSGLHAAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASPVPAPSSGLHAAVR 16 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 AS(1)PVPAPSSGLHAAVR 134.02 3.9192000000000005e-06 4124700.0 1552.5 2406.4 6735.5 6888.5 8259.0 8028.9 7406.5 4677.1 6809.5 4461.5 True False 1815.3075867272928 2645.2914886564404 6896.099864525996 6502.55967781832 6640.708237727569 7607.85034992934 6704.902701583581 4554.331080797081 6909.076055191657 5270.334632785432 0.3444387715790794 0.5019209733288554 1.3084747639413796 1.2338039481150824 1.2600164316735005 1.4435232067813697 1.2721967709363387 0.8641445748939218 1.3109368828711605 1.0 12.363678851407542 -5.2068893971992285 4.93732787417476 1.22024290156365 0.39429555508643116 0.7972662132869697 0.1593253814044329 0.0867410723528132 4.603794654274073 0.04209180247986497 0.11620121600314678 6.210271725483227e-06 5.2068893971992285 -0.8259473464772189 down AS(ph)PVSFQELNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASPVSFQELNR 11 0 F5H212;P15822 F5H212 HIVEP1 Zinc finger protein 40 1 AS(0.998)PVS(0.002)FQELNR;AS(0.999)PVS(0.001)FQELNR;AS(1)PVSFQELNR 94.54700000000001 0.0065881 9355200.0 10285.300000000001 13622.2 18182.9 9262.7 16514.0 14797.1 14632.3 8684.6 10299.599999999999 8066.5 True False 12026.398146065205 14974.521990016512 18616.44929503226 8743.740949078576 13278.200246740898 14021.114027194195 13246.22261532187 8456.638452094312 10450.21216507115 9528.892595621137 1.262098195082161 1.5714860714137795 1.9536844505506523 0.917603054220239 1.393467301000192 1.4714316366245321 1.3901114407994248 0.8874733729269272 1.0966869507872712 1.0 13.218092845110247 -7.713047184208426 7.20097202728055 0.9946317110523808 1.4318911619263037 0.38619256976302263 0.24727006040375324 0.2183623315621611 26.213712135347045 0.12175481153247342 0.06898353753583054 1.936211591542313e-08 7.713047184208426 0.43725945087392293 AS(ph)PVSFQELNR ddPTM_PC-9_Lapatinib_30min_R1 1 ASPVSFQELNR 11 0 F5H212;P15822 F5H212 HIVEP1 Zinc finger protein 40 1 AS(0.956)PVS(0.044)FQELNR 137.81 9.5054e-05 9270900.0 5357.5 9717.0 9008.7 7907.1 6102.3 5269.4 5744.7 4653.0 4742.2 5282.9 True False 5281.101067554827 9694.500883510696 8268.039460587643 8488.614511312351 5743.374711583403 5044.040045571351 6042.132456967022 4869.195366611625 4208.08349842017 6196.042225978227 0.8523345831009165 1.5646279560304537 1.3344065710078807 1.3700059169580907 0.9269424742625351 0.8140745110520936 0.9751599870695029 0.7858557429122233 0.6791566850169102 1.0 12.597131260778239 -6.344338640386882 4.524440748345125 0.8485172119707128 1.3043826833346586 0.5423641019614212 0.1876578358416151 0.16230752359246475 5.996551218174381 0.05770749087029007 0.06626277804029494 4.5254457142933947e-07 6.344338640386882 0.45586547136394573 AS(ph)QEANLLTLAQK ddPTM_PC-9_AZD4547_30min_R2 3 ASQEANLLTLAQK 13 0 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2;H7C1L3 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 AS(1)QEANLLTLAQK;AS(1)QEANLLTLAQK;AS(1)QEANLLTLAQK 157.42 0.00022659 9536100.0 46455.6 40777.0 55250.0 73825.0 59618.0 49646.0 52328.0 59392.0 45875.7 52733.0 True False 61227.514463492604 53957.36781230383 54517.348900291305 56805.78683488009 51341.069781588194 46541.627771812484 56985.0906272318 50214.33109238705 48300.595844902244 50886.83372067599 1.2032093566594821 1.060340443040382 1.0713448826378873 1.116316003206133 1.0089263966275748 0.9146104084071163 1.1198395824749068 0.9867843491308501 0.949176679178549 1.0 15.635004806321623 -1.5228787453359216 0.36552075521125765 0.9895448068115569 3.4468972614671203 0.4999234861946348 0.05895686478619875 58.921725435194986 0.8179628262825265 0.04854758713978507 101.2495049539166 0.02999999999616039 1.5228787453359216 2.457352454655563 AS(ph)QEANLLTLAQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASQEANLLTLAQK 13 0 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2;H7C1L3 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 AS(1)QEANLLTLAQK;AS(1)QEANLLTLAQK 191.96 7.964099999999999e-06 8165900.0 36072.0 34575.7 34708.0 44154.0 50009.0 40076.0 41870.0 48807.0 47001.0 31959.0 True False 42178.27714552455 38008.14699315925 35535.570350823014 41680.19452919944 40210.09544261026 37974.344010234054 37903.77048745083 47525.86796529109 47688.300707843904 37752.91371269522 1.1172191229134512 1.0067606246873126 0.9412669607769486 1.104025899732968 1.0650858831351278 1.0058652505399701 1.0039958975326686 1.258866224921588 1.2631687469411852 1.0 15.204300373302083 -7.754035285198625 24.999823721983258 1.1957631221844032 1.03291012276912 0.3566858375332983 0.08408282452504091 148.64101669161758 501888.71715877875 0.03927913094062648 0.022094357356531372 1.7618328966554333e-08 7.754035285198625 -0.1628529994152832 AS(ph)QEANLLTLAQK ddPTM_PC-9_Lapatinib_30min_R1 2 ASQEANLLTLAQK 13 0 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2;H7C1L3 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 AS(1)QEANLLTLAQK;AS(1)QEANLLTLAQK 199.49 5.2835e-07 6890800.0 18989.1 27886.0 31925.0 31234.0 38114.0 39354.0 38782.0 34004.0 39241.0 31643.0 True False 18718.31195182554 27821.43168031072 29300.249734063782 33531.052553569585 35872.20945500711 37670.92115865466 40789.9421982166 35583.94997770507 34821.26535395087 37112.450388352816 0.5043674496281711 0.7496522430931173 0.7894991957539733 0.9034987504919051 0.9665815401471056 1.0150480705115907 1.0990905146758487 0.9588143495066163 0.9382637090672676 1.0 15.179615639178687 -4.462272751107788 0.6384304142937867 1.0099303059244398 2.2234778430930638e-13 0.9105516167770702 0.04850401166518003 1.4008362154236165 0.3238125547031847 0.024039219790349783 1.1316607351344128 3.4492704585623625e-05 4.462272751107788 -1.0099303059242175 AS(ph)QSRPNSSALETLGGEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASQSRPNSSALETLGGEK 18 1 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 AS(0.43)QS(0.43)RPNS(0.082)S(0.058)ALETLGGEK 68.705 0.028089999999999997 0.0 6564.8 6463.8 8048.8 9216.6 8043.7 8802.8 11642.0 11780.0 8250.9 8063.3 True False 7676.09097928975 7105.483346233994 8240.713917243982 8700.22378262036 6467.594727183594 8341.165671556251 10539.185479219072 11470.78748194172 8371.553803330768 9525.112460952321 0.8058793017675608 0.7459736958867976 0.8651566006203433 0.9133985365827912 0.6790045528278166 0.8757025920429187 1.1064631018713833 1.2042679316349898 0.8788929094170274 1.0 13.217520410958377 -7.133944473589169 4.536514145997405 1.0631088586058304 0.8061155975919774 0.5826758221681909 0.0976514253167312 0.15758520617931715 5.10936021534096 0.03798679919416393 0.029158504398671525 7.346077849068739e-08 7.133944473589169 -0.256993261013853 AS(ph)S(ph)S(ph)LASS(ph)ELMRK ddPTM_PC-9_AZD4547_30min_R2 1 ASSSLASSELMRK 13 1 Q8IZF6;Q8IZF6-3 Q8IZF6 GPR112 Probable G-protein coupled receptor 112 4 AS(0.999)S(0.999)S(0.993)LAS(0.023)S(0.985)ELMRK 64.53399999999999 0.031202999999999998 44444000.0 0.0 0.0 0.0 0.0 0.0 0.0 736.0 0.0 0.0 782.75 True False 0.0 0.0 0.0 0.0 0.0 0.0 801.5025741790739 0.0 0.0 755.3461607505576 0.0 0.0 0.0 0.0 0.0 0.0 1.0611063057269696 0.0 0.0 1.0 9.560994145400436 -13.837240464475089 0.20750866947004543 3.9772859288345015 1.284113686554046e-34 0.43644434687863165 0.30962587209285547 108.80016000598121 1.397449397561458 135.35758228611465 0.7181102516860027 1.4546534306269937e-14 13.837240464475089 -3.9772859288345015 AS(ph)SCETYEYPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSCETYEYPQR 12 0 Q9UQC2-2;Q9UQC2 Q9UQC2-2 GAB2 GRB2-associated-binding protein 2 1 AS(0.411)S(0.411)CET(0.178)YEYPQR 140.63 7.6e-05 6197900.0 9346.4 10024.0 10341.0 10956.0 16089.0 14780.0 14393.0 15642.0 16476.0 12008.0 True False 10928.560920185488 11019.116473691878 10587.568658460888 10342.170839831244 12936.475945852882 14004.910781297016 13029.590843703842 15231.414074068956 16716.93033047033 14184.955344724309 0.7704332269364567 0.7768171422400794 0.7463942184631998 0.7290943530307074 0.9119856659023067 0.9873073577567337 0.9185500078821064 1.0737724373403719 1.1784972123079485 1.0 13.792073988459487 -6.8215503013046455 0.9275899707580255 1.0805813487363938 0.747070293766456 0.8164559010163812 0.06205013340820093 0.23614485511441863 0.435849193817463 0.04019943718912627 0.03481301219006655 1.5081679198394606e-07 6.8215503013046455 -0.3335110549699378 AS(ph)SEDTLNKPGSTAASGVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSEDTLNKPGSTAASGVVR 20 1 Q5M775;Q5M775-2;J3KRD8;J3KRB9;J3KTI9;J3QRQ9;J3QS22 Q5M775 SPECC1 Cytospin-B 1 AS(0.498)S(0.498)EDT(0.003)LNKPGST(0.001)AASGVVR 47.288000000000004 0.033199 15879000.0 11621.0 4616.7 4966.0 9475.4 13674.0 11750.0 8882.6 8346.4 4882.2 9260.0 True False 13588.205774787682 5075.015465292629 5084.408273659875 8944.524057661278 10994.677859630317 11133.809315307175 8041.175823545039 8127.315843741789 4953.592938785038 10938.764697880337 1.2422066065120445 0.46394776791167675 0.4648064396745921 0.8176905075391654 1.005111469466092 1.0178305889937127 0.7351082179419419 0.7429829663779735 0.4528475632851781 1.0 13.417162204986397 -3.6385487490817887 16.439442053002224 0.779845202955359 46.593265414147126 0.0 0.26084261433577155 0.0 0.0 0.06040661124493089 0.0 0.0002298535686659727 3.6385487490817887 45.81342021119177 AS(ph)SFSGISILTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSFSGISILTR 12 0 Q9Y2K5-2;H7C0E9;A0A0U1RRA6;B5MCU0;B5MCG9;Q9Y2K5;H0YIX9;Q9Y2K5-3 Q9Y2K5-2 R3HDM2 R3H domain-containing protein 2 1 AS(0.807)S(0.192)FS(0.001)GISILTR 147.96 0.00014268 7771400.0 20308.0 20072.0 20845.0 22434.0 25262.0 19347.0 17394.0 21242.0 13149.0 14804.0 True False 23745.74329871681 22064.615508773284 21342.02385510271 21177.09571200934 20312.092444784357 18332.40926155301 15746.31439834535 20684.420007759418 13341.279249535954 17487.848011600476 1.3578425020028302 1.26171130342263 1.2203916594509276 1.210960645241291 1.1614975399666347 1.0482941782998285 0.9004146415213645 1.1827881849178077 0.7628885635720349 1.0 14.094065147139018 -6.416040801932709 0.6361621518096379 0.9424770535401248 1.3336785854671507 0.6568552896802271 0.10062682126841627 0.5276700252040465 0.4659614187205679 0.06816566680300071 0.10821396899216458 3.836711979198454e-07 6.416040801932709 0.3912015319270259 AS(ph)SHS(ph)SQTQGGGSVTK ddPTM_PC-9_AZD4547_30min_R2 2 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 AS(0.494)S(0.494)HS(0.617)S(0.39)QT(0.004)QGGGSVTK;AS(0.5)S(0.5)HS(0.374)S(0.252)QT(0.374)QGGGSVTK 151.73 4.2106999999999997e-10 3248800.0 24392.3 25833.5 67368.0 99275.0 81030.0 71204.0 50797.0 80622.0 62521.0 66813.0 True False 32148.54400864157 34183.673673373494 66474.6563025308 76388.68253346048 69780.38317961158 66751.60262385968 55317.834593171756 68163.72240925422 65825.73242084876 64473.8972062944 0.4986288312272676 0.5301940033808944 1.031032079382989 1.1848001415059934 1.082304408500982 1.0353275591558768 0.857988069437987 1.0572297528587986 1.020967170795166 1.0 15.976427571199197 -5.257161865852555 6.3185911615222405 1.037418250477264 0.5099801194899312 0.8811687453050534 0.07629864539265346 0.04522402027439345 9.375739430646032 0.02167906592461936 0.05247746276950774 5.531439085812278e-06 5.257161865852555 -0.5274381309873328 AS(ph)SHSS(ph)QTQGGGSVTK ddPTM_PC-9_AZD4547_30min_R2 1 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 AS(0.97)S(0.026)HS(0.01)S(0.992)QT(0.002)QGGGSVTK 115.63 0.00038578 51666000.0 99339.0 91223.0 217530.0 328260.0 259380.0 239630.0 182410.0 253570.0 176300.0 227240.0 True False 130926.73562043972 120709.05078700725 214645.4100684227 252584.7285664438 223369.5642247036 224645.89821857636 198644.13662500636 214386.58295892717 185618.85807641642 219284.39676647272 0.5970636194415162 0.5504680340551387 0.9788448846956023 1.1518591030233416 1.0186295400788656 1.024449990656715 0.9058744696575596 0.9776645585378266 0.8464754483835506 1.0 17.742443634790817 -5.264765152981839 23.104077389836327 0.9924954528380533 0.5737657485532676 0.8267919303021694 0.07581166193146724 35.843116443601815 249008.8881694889 0.02102880888658949 0.046994460618856315 5.435441763994578e-06 5.264765152981839 -0.41872970428478573 AS(ph)SHSS(ph)QTQGGGSVTK ddPTM_PC-9_Lapatinib_30min_R1 1 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 AS(0.923)S(0.186)HS(0.165)S(0.626)QT(0.099)QGGGSVTK 72.801 0.034883 34504000.0 85130.0 72832.0 143680.0 93295.0 125770.0 147110.0 87501.0 117260.0 153790.0 94529.0 True False 83916.0305890698 72663.36197878481 131867.18502083884 100156.22552299676 118372.45587333389 140818.44823015944 92031.37363431876 122708.32767867608 136468.55071950526 110868.21169802491 0.7568989280501287 0.6554030309129564 1.189404816774798 0.9033809059335717 1.0676861659476253 1.2701426862887524 0.8300970334489329 1.1067945067329168 1.2309078375973879 1.0 16.758486247514142 -5.25484451201024 24.94156158523872 1.0704765427076721 0.7061509408425178 0.5512431484945982 0.133002417448438 362.4235864119527 1370663.9001210537 0.03340890730208658 0.08410464496075384 5.561033201507407e-06 5.25484451201024 -0.3643256018651543 AS(ph)SHSSQTQGGGSVTK ddPTM_PC-9_AZD4547_30min_R2 2 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 AS(0.479)S(0.479)HS(0.017)S(0.019)QT(0.005)QGGGSVTK;AS(0.337)S(0.337)HS(0.163)S(0.163)QTQGGGSVTK 114.55 0.00010834 812940000.0 10731.900000000001 18132.9 131144.0 408390.0 228022.0 167213.0 57975.0 233109.0 89319.0 168206.0 True False 14144.42096261282 23994.005316813997 129404.94487203265 314241.9950626027 196365.08124622313 156757.1446764711 63134.66268754323 197087.3603619215 94040.21999164743 162317.15913792152 0.08714063896716089 0.14782174259485528 0.7972351509804133 1.9359752026930808 1.2097616930282211 0.965745984645246 0.3889586475198069 1.2142114943895463 0.5793609282660073 1.0 17.308455994930505 -5.324735813186688 4.110952060140781 1.0469515902682756 0.10580369178961938 0.46300101401741245 0.3903776035072978 0.19146791227778587 6.455543775859092 0.11027986985107313 0.25661992132350886 4.7343917040377865e-06 5.324735813186688 -0.9411478984786562 AS(ph)SHSSQTQGGGSVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 AS(0.387)S(0.387)HS(0.176)S(0.048)QT(0.001)QGGGSVTK 55.851000000000006 0.036227999999999996 1495600.0 1972.5 1064.4 19111.0 7542.2 8646.6 16801.0 7361.2 12950.0 13887.0 7792.4 True False 2306.40529134917 1170.066597625463 19566.678718871106 7119.634986142316 6952.360800137453 15919.925983529856 6663.893845527182 12610.076221659181 14090.07110337714 9205.100435395538 0.2505573195573792 0.12711068236977752 2.1256344627846895 0.7734445741369458 0.7552726718118328 1.729467928705526 0.7239349415355769 1.3699009924075134 1.5306808657076536 1.0 13.168217747340647 -5.222767236294402 24.980113700035236 1.227751178922524 0.18883317605790445 0.4849315043926897 0.4373601295717877 447.01292153563406 288744.832129396 0.10736252725160156 0.28404303957699034 5.987324046474171e-06 5.222767236294402 -1.0389180028646194 AS(ph)SHSSQTQGGGSVTK ddPTM_PC-9_Lapatinib_30min_R1 4 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 AS(0.524)S(0.119)HS(0.307)S(0.051)QTQGGGSVTK;AS(0.485)S(0.485)HS(0.028)S(0.002)QTQGGGSVTK;AS(0.735)S(0.201)HS(0.056)S(0.008)QTQGGGSVTK;AS(0.482)S(0.482)HS(0.029)S(0.007)QTQGGGSVTK 124.2 2.0511e-05 434571300.0 71635.0 57695.0 190178.0 65827.2 126048.0 182835.0 106359.0 116629.0 255429.0 101928.0 True False 70613.47176375001 57561.41077227026 174542.29894830933 70668.35188110183 118634.10445990287 175015.57325920204 111865.74860141621 122048.00911509714 226659.89623338633 119546.11898947721 0.5906797507158356 0.48149961921672235 1.4600415339595678 0.5911388213892771 0.9923710235239455 1.4640004605637378 0.9357539127745582 1.0209282421442736 1.8960038029619144 1.0 16.86720776880655 -4.741199520910964 0.4439525622158717 1.2768824803839758 2.3418019154413148e-17 0.2989620914377267 0.3571208962929385 7.04524017359888 1.054486690798261 0.2603993160001875 4.8172404182081685 1.814681781249823e-05 4.741199520910964 -1.2768824803839758 AS(ph)SHSSQTQGGGSVTKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSHSSQTQGGGSVTKK 17 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 AS(0.897)S(0.088)HS(0.007)S(0.006)QT(0.002)QGGGSVTKK 49.592 0.039741000000000005 4272600.0 3174.0 1107.5 5998.5 6424.4 12393.0 16271.0 8283.8 6820.1 10160.0 5862.1 True False 3711.2955106424656 1217.4452807874866 6141.52698943793 6064.461696185823 9964.680613894885 15417.720116541539 7499.098494481613 6641.079601493264 10308.570779168413 6924.852325641935 0.5359385783433913 0.1758081217529255 0.8868820157646624 0.8757532162425783 1.4389737347895224 2.226433054673453 1.082925402858529 0.9590211154253943 1.488634023428479 1.0 12.757567590288073 -5.75199211559937 1.7044214442045813 1.3783168576571119 0.37563292801625137 0.5225650069338001 0.3670648885511742 0.3003994464854001 1.7727530337403654 0.12267317794085322 0.2639088201850159 1.7701410940581535e-06 5.75199211559937 -1.0026839296408605 AS(ph)SHSSQTQGGGSVTKK ddPTM_PC-9_Lapatinib_30min_R1 1 ASSHSSQTQGGGSVTKK 17 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 AS(0.794)S(0.162)HS(0.036)S(0.009)QT(0.001)QGGGSVTKK 57.788000000000004 0.016275 3726900.0 6542.5 3498.6 18380.0 2760.5 10364.0 17658.0 5654.6 8473.9 31560.0 8729.5 True False 6449.202750252442 3490.499206653341 16868.867348851752 2963.516378758046 9754.409896407971 16902.808502808468 5947.367519829705 8867.62832949286 28005.380458466658 10238.382443672404 0.6299044586128175 0.34092291686276704 1.6476105909949834 0.28945161943912134 0.9527295888850547 1.6509256804774721 0.5808893692484928 0.8661161446428769 2.7353325207904042 1.0 13.321700182306527 -8.21451311295698 24.28033585560147 1.8676665699922743 0.8779389656094037 0.31360224487605626 0.5904057199018551 289.5983423386314 149842.69985014183 0.3773875662125698 0.14263791597009054 6.10220631548267e-09 8.21451311295698 -0.9897276043828707 AS(ph)SKGGGGYTCQSGSGWDEFTK ddPTM_PC-9_AZD4547_30min_R2 2 ASSKGGGGYTCQSGSGWDEFTK 22 1 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 AS(0.344)S(0.274)KGGGGY(0.344)T(0.038)CQSGSGWDEFTK;AS(0.352)S(0.311)KGGGGY(0.173)T(0.032)CQS(0.087)GS(0.046)GWDEFTK 77.668 0.00033454 30183000.0 50113.0 39310.0 60652.0 100152.0 79720.0 55719.0 54709.0 59392.0 48000.0 62264.0 True False 66047.8915848466 52016.18875105241 59847.71485068722 77063.50373297546 68652.25406736585 52234.88212177456 59577.995014623615 50214.33109238705 50537.18200605782 60084.15631168664 1.0992563703852822 0.8657222127114237 0.9960648284753658 1.2825927576183052 1.142601615494644 0.8693619970430481 0.991575794217076 0.8357333143183395 0.8411066262442984 1.0 15.874696994047069 -6.76913725526288 24.999990003860482 0.9025401227364881 1.0723940676052572 0.3644048732916737 0.111864832307562 219.5642159919703 713062.8245728633 0.04274115493495118 0.03839670985366646 1.7016206399469626e-07 6.76913725526288 0.16985394486876915 AS(ph)SLEDLVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSLEDLVLK 10 0 Q15477 Q15477 SKIV2L Helicase SKI2W 1 AS(0.584)S(0.416)LEDLVLK 89.805 0.022357 0.0 4440.9 6570.3 7411.6 6905.7 6357.2 5097.8 7005.0 6814.4 6877.8 7103.8 True False 5192.656658226883 7222.5559624000125 7588.320652649521 6518.796017581473 5111.552295542043 4830.462393835992 6341.435688191858 6635.529220453618 6978.374813480753 8391.662706350136 0.6187875799985977 0.8606823480803825 0.9042690248867236 0.7768181641343345 0.6091227060012827 0.5756263761865317 0.7556828616804593 0.7907287807733719 0.8315842828382604 1.0 13.034740976202713 -8.603898964101173 1.4114849426960243 0.9979286403925041 0.7342125365071869 0.39775322732823637 0.10121334745233439 0.6159415890245217 2.6388015189041667 0.10811084630137753 0.032161095295775884 2.4894364027509013e-09 8.603898964101173 -0.2637161038853172 AS(ph)SLGEIDESSELR ddPTM_PC-9_AZD4547_30min_R2 3 ASSLGEIDESSELR 14 0 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 AS(0.654)S(0.346)LGEIDESSELR;AS(0.5)S(0.5)LGEIDESSELR;AS(0.663)S(0.337)LGEIDESSELR 255.39 1.0038999999999999e-44 222727000.0 104860.0 112631.0 141359.0 202372.0 174326.0 143885.0 133038.0 178661.0 141816.0 133126.0 True False 138203.29877650522 149036.7681307499 139484.48729767016 155718.26201623207 150123.84398579542 134887.84820423092 144878.12427124433 151053.04767135272 149312.10423689787 128465.29926040076 1.075802567480619 1.1601324948354381 1.085775599330784 1.2121426012528815 1.1685945142391527 1.0499944263610952 1.127760765789169 1.1758276245880712 1.1622757670477253 1.0 16.971019189142197 AS(ph)SLGEIDESSELR ddPTM_PC-9_Lapatinib_30min_R1 3 ASSLGEIDESSELR 14 0 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 AS(0.627)S(0.373)LGEIDESSELR;AS(0.5)S(0.5)LGEIDESSELR;AS(0.661)S(0.339)LGEIDESSELR 236.42 6.535400000000001e-27 154397000.0 79107.0 67187.0 92124.0 67998.0 81447.0 82978.0 78756.0 80112.0 99635.0 73399.0 True False 77978.91967355285 67031.43262945696 84549.92032892359 72998.7997546785 76656.44759096297 79429.22437116553 82833.60032393239 83834.29598323471 88413.05709693678 86085.91935198005 0.9058266469191082 0.7786573359969023 0.9821573721391508 0.8479760720938327 0.8904644123917324 0.9226738236528875 0.9622200813730074 0.9738444639298198 1.027032733837014 1.0 16.393489661976247 -7.322245175292306 0.9617062862015134 1.0126657939503396 0.8742456915065644 0.5481303430222 0.04839064503947326 0.4234591444296695 0.7509332537580983 0.03580083122669862 0.019550922212278474 4.761620998036382e-08 7.322245175292306 -0.13842010244377523 AS(ph)SLNENVDHSALLK ddPTM_PC-9_AZD4547_30min_R2 1 ASSLNENVDHSALLK 15 0 Q96SB3 Q96SB3 PPP1R9B Neurabin-2 1 AS(0.881)S(0.119)LNENVDHSALLK 102.5 0.00083117 9660100.0 36315.0 38098.0 43110.0 69150.0 59593.0 65050.0 46572.0 81548.0 53122.0 48138.0 True False 47862.41460107571 50412.43345300415 42538.33323242641 53208.53585685003 51319.5406000568 60982.41321670228 50716.81777808134 68946.63038661743 55929.92046928755 46452.703272066836 1.0303472398743383 1.0852421904866492 0.915734289634028 1.145434648769852 1.1047697331947635 1.3127850247925728 1.0917947547861788 1.4842328977671522 1.2040186367995422 1.0 15.50347493490279 -6.340840752136261 1.663850489617667 1.2404830724845932 1.0233636083105029 0.27308628500654597 0.13232917239765105 0.42513945844419365 2.3385281985788797 0.046752549665083395 0.05895244194545197 4.562041670310424e-07 6.340840752136261 -0.21711946417409034 AS(ph)SLNVLNVGGK ddPTM_PC-9_AZD4547_30min_R2 1 ASSLNVLNVGGK 12 0 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;H0YJK1 Q07866-6 KLC1 Kinesin light chain 1 1 AS(0.625)S(0.375)LNVLNVGGK 173.33 0.0011823 450660000.0 689020.0 697330.0 1008000.0 1299400.0 956090.0 861900.0 916570.0 1032300.0 845390.0 904430.0 True False 908114.0274936869 922728.2854686189 994633.2613844997 999843.4055298765 823353.406814699 808005.2567482813 998142.954368631 872781.7548941133 890075.5895021087 872766.1809870686 1.0405009351607106 1.0572456925691653 1.139633137777639 1.1456028284678583 0.9433837203493776 0.9257980824078852 1.1436544817075356 1.0000178443062804 1.0198328130627883 1.0 19.735235673866974 -6.255228413783931 24.996753256509056 1.008376561569666 1.0961304709568223 0.33604390700904985 0.06209778121035942 675.8181734338845 2719906.497383984 0.019687807244168957 0.024801192069699027 5.556119606491443e-07 6.255228413783931 0.08775390938715621 AS(ph)SMPATLLHSR ddPTM_PC-9_AZD4547_30min_R2 3 ASSMPATLLHSR 12 0 Q5T7N3 Q5T7N3 KANK4 KN motif and ankyrin repeat domain-containing protein 4 1 AS(0.5)S(0.5)MPATLLHSR;AS(0.5)S(0.5)MPATLLHSR;AS(0.5)S(0.5)MPATLLHSR 87.447 0.010329000000000001 12405500.0 54048.0 44699.0 79116.0 116820.0 93493.0 81223.0 60517.0 100691.0 67917.0 84262.0 True False 71234.139731762 59147.07761341368 78066.87014652388 89888.95385100826 80513.11075665127 76144.1129700265 65902.89576303668 85131.51959899538 71506.95396469645 81312.01302735691 0.8760592325736141 0.7274088466302516 0.9600902405436548 1.1054818409275602 0.9901748555845388 0.9364435848416187 0.8104939640451906 1.0469734597562284 0.8794143854320566 1.0 16.31118089119392 -5.283183583430427 21.498464696257255 0.9670281181320974 0.8017341561857151 0.3771838160493297 0.0844954054315602 121.41005572899604 120038.38443006537 0.022535980696753166 0.04704110930301677 5.2097444007588e-06 5.283183583430427 -0.16529396194638235 AS(ph)SMPATLLHSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASSMPATLLHSR 12 0 Q5T7N3 Q5T7N3 KANK4 KN motif and ankyrin repeat domain-containing protein 4 1 AS(0.5)S(0.5)MPATLLHSR;AS(0.5)S(0.5)MPATLLHSR;AS(0.5)S(0.5)MPATLLHSR 89.911 0.0050164 7644200.0 54752.0 53197.0 63182.0 64634.0 75321.0 72477.0 64328.0 62070.0 57027.0 49960.0 True False 64020.43219870707 58478.04659327487 64688.49849906931 61012.76652625526 60562.39074632256 68676.17853153343 58234.386145611126 60440.72826860121 57860.91199051542 59017.35251685758 1.0847730280754364 0.990861909242224 1.0960928564288248 1.0338106323699918 1.026179389002983 1.1636607811561341 0.9867332854176607 1.0241179194091612 0.980405076184808 1.0 15.848851583334117 AS(ph)SMPATLLHSR ddPTM_PC-9_Lapatinib_30min_R1 1 ASSMPATLLHSR 12 0 Q5T7N3 Q5T7N3 KANK4 KN motif and ankyrin repeat domain-containing protein 4 1 AS(0.5)S(0.5)MPATLLHSR 134.06 3.9e-05 4808100.0 29235.0 22998.0 25636.0 22154.0 27305.0 26132.0 20979.0 24619.0 30191.0 18295.0 True False 28818.10353895761 22944.749543992904 23528.307037821753 23783.27906357754 25698.973583695475 25014.39527666727 22065.18996896464 25762.88861607817 26790.571654675747 21457.266373444832 1.3430463618899018 1.069323050973024 1.0965193155704125 1.108402097902431 1.1976816215275266 1.165777356785051 1.028331828711982 1.2006603342521722 1.2485547407768274 1.0 14.389178669964442 -11.94436613462015 1.9265239401962397 6.345267952854663e-05 1.1541642933348648 0.2300349238750944 0.08787805216095779 1950268.5131319594 183317.30014826002 8477405.523535453 0.021834422987433905 1.1366686063467541e-12 11.94436613462015 1.1541008406553364 AS(ph)SPAQCVTPVQTVV ddPTM_PC-9_AZD4547_30min_R2 4 ASSPAQCVTPVQTVV 15 0 Q13614;Q13614-2 Q13614 MTMR2 Myotubularin-related protein 2 1 AS(0.5)S(0.5)PAQCVTPVQTVV;AS(0.635)S(0.365)PAQCVTPVQTVV;AS(0.5)S(0.5)PAQCVTPVQTVV;AS(0.5)S(0.5)PAQCVTPVQTVV 132.51 6.4902999999999995e-06 27820700.0 56497.9 52630.0 76328.0 85572.0 77185.0 76363.0 60277.0 76013.0 61430.0 72093.0 True False 74463.0569706765 69641.61826425557 75315.84084817079 65844.69747422087 66469.19506008072 71588.00953830947 65641.53622797831 64266.93745497069 64677.06438816942 69569.0460134015 1.0703475358327068 1.001043168693733 1.082605629429822 0.946465436101234 0.9554420948546047 1.0290210034577598 0.9435451539084407 0.923786383998863 0.9296816342099946 1.0 16.086157916997784 -5.770885539279043 24.999007159955106 0.9598174806011338 1.0463032194486208 0.5663014681144629 0.03607888012631221 146.513783604102 387745.31083934923 0.010390998606123665 0.01565097484592328 1.6947844114287051e-06 5.770885539279043 0.086485738847487 AS(ph)SPAQCVTPVQTVV ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ASSPAQCVTPVQTVV 15 0 Q13614;Q13614-2 Q13614 MTMR2 Myotubularin-related protein 2 1 AS(0.5)S(0.5)PAQCVT(0.001)PVQTVV;AS(0.782)S(0.218)PAQCVTPVQTVV;AS(0.574)S(0.422)PAQCVT(0.004)PVQTVV;AS(0.551)S(0.449)PAQCVTPVQTVV 123.72 0.00011722 14685900.0 81633.0 82504.0 85733.0 98762.0 117012.0 89577.0 90505.0 91020.0 86772.0 65998.0 True False 95451.85457475617 90694.45187005932 87777.19986421296 93228.68533072397 94084.33857767026 84879.42442870379 81931.7112005431 88630.82144366174 88040.87634350423 77962.91496011938 1.2243238291382892 1.163302474214215 1.125884016895904 1.1958081015623074 1.2067832331025274 1.0887153779732637 1.0509062063989512 1.1368330890269989 1.1292660925844047 1.0 16.250500412165387 -6.772450761422333 24.905382387527546 1.0878063231270139 1.17962775177362 0.5711119274668146 0.04398499886713004 173.36296919807626 392107.41507159994 0.015576345623898208 0.013868289526900222 1.6886873052710122e-07 6.772450761422333 0.09182142864660614 AS(ph)SPAQCVTPVQTVV ddPTM_PC-9_Lapatinib_30min_R1 3 ASSPAQCVTPVQTVV 15 0 Q13614;Q13614-2 Q13614 MTMR2 Myotubularin-related protein 2 1 AS(0.499)S(0.499)PAQCVT(0.002)PVQTVV;AS(0.5)S(0.5)PAQCVTPVQTVV;AS(0.5)S(0.5)PAQCVTPVQTVV 136.17 2.9247e-05 22486700.0 49366.0 62372.0 72893.0 58983.0 64717.0 59953.0 53601.0 52243.0 64134.0 48390.0 True False 48662.03178738435 62227.58146612422 66900.01891511717 63320.806581519966 60910.473298517456 57388.94994726898 56376.19750829276 54670.40050244818 56910.553559039894 56754.14702437798 0.8574180802414709 1.09644113652867 1.1787688199486315 1.1157036076028306 1.0732338779112334 1.0111851372309115 0.9933405832718643 0.9632846825971193 1.0027558608993759 1.0 15.792438193502154 -6.859200052643211 3.252290712696528 0.9881297061408931 1.0757810332160698 0.16362234830049194 0.07831462642484388 0.4226032346379345 8.874499512408452 0.030584371880531265 0.026980191578542607 1.3829292021635168e-07 6.859200052643211 0.08765132707517664 AS(ph)SPCHSPR ddPTM_PC-9_Lapatinib_30min_R1 1 ASSPCHSPR 9 0 A0A494BYR6;Q86Y91-6;Q86Y91 A0A494BYR6 KIF18B Kinesin-like protein KIF18B 1 AS(0.591)S(0.409)PCHSPR 89.171 0.0054132 12617000.0 38280.0 51887.0 81269.0 44656.0 67984.0 43368.0 56798.0 69763.0 76650.0 49808.0 True False 37734.12018030778 51766.85883942776 74587.37652741192 47940.15120804903 63985.31478168654 41513.25173574569 59738.72252525162 73004.44366235269 68016.86983971701 58417.246435011744 0.6459414382409548 0.8861571196618719 1.2768040446820648 0.8206506491431719 1.095315487916213 0.7106334904355432 1.022621334809233 1.2497070320417956 1.164328584288626 1.0 15.834106736207172 -7.52915008310123 16.864279016266746 1.151450362872728 0.9216120989089659 0.25016290987482015 0.17917817301389996 4.392485596263915 11793.521216338857 0.08330566980735037 0.04866612275246841 2.9569904158411032e-08 7.52915008310123 -0.22983826396376206 AS(ph)SPEKAEEDR ddPTM_PC-9_AZD4547_30min_R2 1 ASSPEKAEEDR 11 1 Q8N3D4;H0YDZ9 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 AS(0.5)S(0.5)PEKAEEDR 56.205 0.038488 15988000.0 53016.0 65849.0 50906.0 60645.0 55884.0 52144.0 49844.0 39623.0 53826.0 51854.0 True False 69873.98519869559 87133.4015026215 50230.953178610485 46664.23220590994 48125.47122805656 48883.42743692123 54280.01943937744 33500.17579595993 56671.132472043086 50038.607243129205 1.3964014797452218 1.7413234760762808 1.0038439506229002 0.9325645691770807 0.9617668012665292 0.9769142294349811 1.084762794768446 0.669486575299512 1.1325481581988794 1.0 15.61075401414923 -5.297598143276167 9.188334551523072 0.9606769728871538 1.5685687431230904 0.7472963194880042 0.13915834844406355 0.164587351339975 40.80697964342698 0.03391586589589309 0.07148754712191417 5.039667181991174e-06 5.297598143276167 0.6078917702359365 AS(ph)SPEKAEEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSPEKAEEDR 11 1 Q8N3D4;H0YDZ9 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 AS(0.737)S(0.263)PEKAEEDR 142.89 0.00070243 10131000.0 15796.0 15563.0 14486.0 15800.0 17039.0 14682.0 14620.0 14483.0 12664.0 9802.7 True False 18469.950814778935 17107.99178771616 14831.401178460927 14914.777224291136 13700.330265484934 13912.05007381617 13235.087760366167 14102.836596006953 12849.18704206581 11579.851911869493 1.595007514374774 1.47739296822788 1.2807936829708984 1.2879937790053517 1.1831179163389753 1.2014013805786363 1.1429410204114991 1.2178771113256956 1.1096158344559859 1.0 13.499329183189415 -1.5228787452803376 0.3179222105093603 1.090468559972617 6.083633587166916 0.9182638702202174 0.04738142704938114 14.545113168582397 0.20764100416894274 0.04435609575974623 42.13228599190877 0.029999999999999995 1.5228787452803376 4.993165027194299 AS(ph)SPFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSPFR 6 0 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 AS(0.5)S(0.5)PFR 82.671 0.045598 48904000.0 26472.0 40532.0 41081.0 33363.0 38405.0 21211.0 33129.0 27005.0 29887.0 23938.0 True False 30953.186754167393 44555.74909334388 42060.52684056008 31493.779274305376 30879.81594259927 20098.65782016854 29990.781286810565 26296.147364162643 30324.040834351006 28277.769906896272 1.0946120170041644 1.5756457896093778 1.4874060783096803 1.113729243076725 1.0920173706862373 0.7107582346961158 1.0605780224379198 0.9299229554077969 1.0723632356509025 1.0 14.787380727733389 -5.995030714298636 2.634594372278842 0.9648631516799566 1.402822275491081 0.5740724872855238 0.15546862914555912 0.18521895108338488 2.595052157582785 0.0470010019327825 0.07109417708595094 1.0115079155779587e-06 5.995030714298636 0.43795912381112445 AS(ph)SPGYIDSPTYSR ddPTM_PC-9_AZD4547_30min_R2 1 ASSPGYIDSPTYSR 14 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 AS(0.958)S(0.042)PGYIDSPTYSR 210.38 3.2688e-11 26703000.0 49698.0 45930.0 72282.0 87139.0 81119.0 76217.0 63582.0 75814.0 67964.0 65707.0 True False 65500.93021738296 60775.97428989661 71323.49345178022 67050.4498341295 69857.02706586364 71451.13894138965 69240.67482534485 64098.68833240555 71556.43828874396 63406.61792965429 1.0330298690596016 0.9585115288332171 1.1248588204295837 1.0574676906520675 1.1017308499779264 1.1268719460902372 1.0920102204814501 1.0109147976244226 1.128532645726845 1.0 15.952345805971197 -5.259487438566712 24.99997578578065 1.082719872210435 0.9957706978837247 0.3442759237623343 0.046566456649432 170.875699731953 2188490.6667751595 0.011408367383404573 0.027242113101898537 5.501898338442572e-06 5.259487438566712 -0.08694917432671023 AS(ph)SPGYIDSPTYSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSPGYIDSPTYSR 14 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 AS(0.937)S(0.063)PGYIDSPTYSR 212.83 1.0917e-12 26890000.0 19886.0 16543.0 28078.0 28788.0 30775.0 25732.0 25812.0 21965.0 20004.0 16811.0 True False 23252.307033596742 18185.279711121795 28747.48600640798 27175.10169195527 24744.859670186 24382.568621402916 23366.90049730311 21388.442023841228 20296.52065615009 19858.70122419723 1.1708876009104012 0.9157335872984271 1.4476015164264637 1.3684229086866582 1.2460462238102024 1.2278027825754028 1.176658041908161 1.0770312611269892 1.0220467303984306 1.0 14.277483652029002 -7.806925938464763 1.7130320721773582 1.007390497842863 1.232726597458459 0.32153897928125363 0.1300957251240802 0.5080352817316642 2.8188996571743705 0.11035858550648765 0.04215720228338269 1.559818480651996e-08 7.806925938464763 0.22533609961559598 AS(ph)SPIKQSHEPVPDTSVEK ddPTM_PC-9_Lapatinib_30min_R1 3 ASSPIKQSHEPVPDTSVEK 19 1 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 AS(0.472)S(0.429)PIKQS(0.098)HEPVPDTSVEK;AS(0.333)S(0.333)PIKQS(0.333)HEPVPDTSVEK;AS(0.442)S(0.442)PIKQS(0.117)HEPVPDTSVEK 54.974 0.013469 67071000.0 200550.0 122716.0 164703.0 134585.0 147705.0 140909.0 108407.0 110094.0 138573.0 101367.0 True False 197690.12022363392 122431.85864164864 151161.7551119655 144482.8298623987 139017.28229920307 134882.65054492236 114019.78402047516 115209.36915790712 122965.44950161905 118888.15088696279 1.6628244173096354 1.0298070726834263 1.2714619075511402 1.2152836828942775 1.1693115021309297 1.13453400981202 0.9590508656231317 0.9690567840309552 1.0342952479640541 1.0 16.859245408961357 -1.5228787452803376 0.40904758339068775 1.014596665757734 9.42908002551786 0.6263451013889891 0.12253797752262949 54.32327479665045 0.7098825134701304 0.0871038727607416 370.9773523126675 0.029999999999999995 1.5228787452803376 8.414483359760126 AS(ph)SPPDRIDIFGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASSPPDRIDIFGR 13 1 Q9NWB6-2;Q9NWB6 Q9NWB6-2 ARGLU1 Arginine and glutamate-rich protein 1 1 AS(0.5)S(0.5)PPDRIDIFGR;AS(0.569)S(0.431)PPDRIDIFGR 75.968 0.0083826 111220000.0 34758.0 22469.2 34361.0 48797.0 49365.0 66037.0 49381.0 53022.0 51793.0 36736.0 True False 40641.842898207564 24699.793682230415 35180.29655481817 46063.062292008544 39692.282619617574 62573.90346850553 44703.2741925199 51630.22868145277 52550.37464227061 43395.945997983996 0.9365354749979554 0.5691728366372718 0.810681637322816 1.0614600334821243 0.9146541619685286 1.4419297017148207 1.0301255834956713 1.1897477401195795 1.210951240576986 1.0 15.405272653514485 -5.948298562325811 1.536868515287826 1.1620450488431235 0.7366734249061512 0.5097663458068503 0.15820138311820572 0.29024024861046405 1.3910503200010074 0.05169505372966758 0.09423128950134588 1.1264228134955481e-06 5.948298562325811 -0.42537162393697237 AS(ph)SPSEHGPR ddPTM_PC-9_AZD4547_30min_R2 1 ASSPSEHGPR 10 0 C9J052;Q9NSU2-2;Q9NSU2;Q9NSU2-1 C9J052 TREX1 Three-prime repair exonuclease 1 1 AS(0.575)S(0.398)PS(0.028)EHGPR 77.387 0.012375 3016700.0 989.04 427.45 5112.0 8087.4 4971.2 5795.4 2715.7 6892.0 3364.4 6009.1 True False 1303.5341466900159 565.6148532596626 5044.21153987854 6222.974879084443 4281.034689158161 5433.012721845913 2957.3920389920013 5826.999762404556 3542.2353154412685 5798.723238027694 0.22479675148858871 0.09754127418090812 0.8698831333764803 1.0731629401235312 0.7382719459834506 0.9369325796093402 0.5100074477770545 1.0048763362582003 0.6108646972856875 1.0 12.50151956749985 -5.263125475915916 24.988817541494274 0.839116032122645 0.1611689674256403 0.7143906913741092 0.17243272679371396 67.85290119094664 1005632.7643393307 0.04273508113122462 0.09708598350420751 5.456002040664046e-06 5.263125475915916 -0.6779470646970047 AS(ph)SPSEHGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASSPSEHGPR 10 0 C9J052;Q9NSU2-2;Q9NSU2;Q9NSU2-1 C9J052 TREX1 Three-prime repair exonuclease 1 1 AS(0.5)S(0.5)PSEHGPR;AS(0.333)S(0.333)PS(0.333)EHGPR 130.1 0.00012716 6550800.0 2295.2 6966.0 21224.2 18985.6 25691.7 21980.0 17128.4 12371.0 18740.5 13404.3 True False 2683.732027733644 7657.538443309819 21730.265421226726 17921.898384145676 20657.59581441162 20827.330106421417 15505.873953122818 12046.274358157976 19014.544358957242 15834.393481619583 0.1694875165789517 0.48360162656047534 1.3723459282763824 1.1318335877499348 1.3046029100129894 1.3153222528287924 0.9792527873657991 0.7607663894509872 1.2008381868891378 1.0 13.95077398718598 -5.0970856672559455 4.2073595347884085 1.1297918249893317 0.2273727461319991 0.7737917120987414 0.17762117571875558 0.10164701813138632 3.0560123455928436 0.04961513613456121 0.15505860772446364 7.99676498343796e-06 5.0970856672559455 -0.9024190788573326 down AS(ph)SPSPLTIGTPESQR ddPTM_PC-9_Lapatinib_30min_R1 1 ASSPSPLTIGTPESQR 16 0 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 AS(0.751)S(0.19)PS(0.036)PLT(0.021)IGT(0.003)PESQR 63.754 0.032152999999999994 4971500.0 23429.0 21220.0 23809.0 16674.0 26154.0 25975.0 14505.0 25557.0 26608.0 21973.0 True False 23094.898163647613 21170.866393752916 21851.51592539778 17900.26158283344 24615.673140742394 24864.109800682414 15255.997926489916 26744.471520415515 23611.126845338415 25771.003772817894 0.8961582702497247 0.8214994875784777 0.8479109357954379 0.6945892267383794 0.9551693584673605 0.9648095208036859 0.5919830698477202 1.0377737614017344 0.9161896468403136 1.0 14.653461110377712 AS(ph)SSDMGSTAK ddPTM_PC-9_Lapatinib_30min_R1 1 ASSSDMGSTAK 11 0 K7EJ41;Q13472-3;Q13472-2;Q13472 K7EJ41 TOP3A DNA topoisomerase 3-alpha 1 AS(0.668)S(0.33)S(0.001)DMGS(0.001)T(0.001)AK 79.23 0.017509999999999998 2518300.0 7452.4 9441.3 10170.0 9722.2 15779.0 13306.0 21357.0 20747.0 20739.0 16934.0 True False 7346.127409397214 9419.439249921747 9333.861857335269 10437.203020308454 14850.910242707585 12736.933397800958 22462.760959396423 21710.981360647216 18403.155428648275 19861.01933686334 0.3698766556136585 0.4742676642199656 0.469958852515239 0.5255119509871443 0.7477415932596839 0.6413031064402814 1.1309973863075637 1.093145371463902 0.9265967227820389 1.0 14.277652048463024 -6.757682688194873 1.0350864990649324 1.052201133052959 0.43680016421778983 0.8636668464630783 0.09882075389252433 0.1750899251397418 0.4014366369335469 0.055537406991018626 0.050598104934302834 1.7470981820361495e-07 6.757682688194873 -0.6154009688351691 down AS(ph)SSGPRSPLDQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSSGPRSPLDQR 13 1 O14646;O14646-2 O14646 CHD1 Chromodomain-helicase-DNA-binding protein 1 1 AS(0.46)S(0.46)S(0.007)GPRS(0.074)PLDQR 54.812 0.03768 38174000.0 31882.0 33279.0 39024.0 43432.0 48555.0 46288.0 58759.0 42559.0 43856.0 44335.0 True False 37278.99290179682 36582.71918675103 39954.480159344166 40998.645848443826 39040.99630498394 43860.57579463308 53192.92214167958 41441.87134498787 44497.311032599355 52372.58454433313 0.7118035748310328 0.6985089528240475 0.7628892197505147 0.7828264769659913 0.7454471961744782 0.837472051002282 1.0156634927316226 0.7912894065769761 0.8496298477485411 1.0 15.67652418191713 -6.89051547295493 3.7907038100953905 0.9002078229019885 0.7413745771848538 0.6059450861883682 0.06564526533176392 0.1751967877532907 4.765511848775473 0.024550212866076636 0.021468549767299387 1.2867214091659596e-07 6.89051547295493 -0.15883324571713475 AS(ph)SVTTFTGEPNTCPR ddPTM_PC-9_AZD4547_30min_R2 3 ASSVTTFTGEPNTCPR 16 0 H0YFA4;P52943;P52943-2 H0YFA4 CRIP2 Cysteine-rich protein 2 1 AS(0.933)S(0.067)VTTFTGEPNTCPR;AS(0.492)S(0.492)VT(0.016)TFTGEPNTCPR;AS(0.729)S(0.268)VT(0.003)TFTGEPNTCPR 211.75 9.5995e-18 56048000.0 116539.0 116337.0 150469.0 215012.0 207816.0 146638.0 165647.0 207983.0 159994.0 166130.0 True False 153595.97783821443 153940.66015597014 148473.68274530195 165444.30530228568 178964.33556527423 137468.7026790282 180389.26209924088 175844.00632388063 168450.95620577535 160313.83926603632 0.9580955614401213 0.9602456086184171 0.9261438901660514 1.0320026396956004 1.1163374065809 0.8574974144989613 1.125225762947951 1.096873527132442 1.0507574204260415 1.0 17.290539447519222 -5.821368960673445 6.6424242321968014 1.0435580264551585 0.9495420786412001 0.2520641436382832 0.072244163847013 0.2844307503502879 24.390053823965342 0.020553675431122707 0.03095831931750507 1.5087977902166114e-06 5.821368960673445 -0.09401594781395839 AS(ph)SWPHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSWPHR 7 0 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 AS(0.945)S(0.055)WPHR 83.265 0.012101 0.0 14235.0 20470.0 28228.0 20968.0 31421.0 24309.0 23014.0 22676.0 19080.0 16544.0 True False 16644.704345934308 22502.126318482915 28901.062575286156 19793.230939173194 25264.280607535784 23034.193246451236 20833.947313068868 22080.779027208002 19359.008904186347 19543.296237768052 0.851683571871969 1.151398722340238 1.4788223144995325 1.0127887690164639 1.2927338510435995 1.178623757538757 1.0660406033659047 1.1298390383366437 0.9905703044491766 1.0 14.254386197153732 -7.963323220553862 1.2418294772755072 0.9937865115630292 1.1705398070279587 0.12291023627602549 0.156833487918241 0.962937858117038 2.67678934190506 0.14188630589025936 0.04970614988850104 1.0881199664230747e-08 7.963323220553862 0.17675329546492946 AS(ph)TASASAAVSAARPR ddPTM_PC-9_Lapatinib_30min_R1 1 ASTASASAAVSAARPR 16 1 E9PC69;Q7KZI7-14;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 AS(0.99)T(0.009)AS(0.001)ASAAVSAARPR 112.12 0.0018453 5467100.0 17592.0 23370.0 18922.0 20533.0 19695.0 19848.0 17291.0 14628.0 19752.0 13448.0 True False 17341.13485402232 23315.888200848505 17366.30620103226 22043.065316080054 18536.578821859817 18999.14730794782 18186.243374487236 15307.670282139461 17527.32176221905 15772.468881666367 1.099455956079225 1.4782649676329667 1.1010518601319632 1.397565941100224 1.175249034309803 1.204576623386595 1.1530372011465242 0.9705310181294965 1.1112605067550643 1.0 13.94512088397416 -7.319714025553677 1.2276706489880094 1.023490549719753 1.2674074479125137 0.3962671133816347 0.11788558881816456 0.44511158066940604 1.2948358745769686 0.07378984360117101 0.04023738817003621 4.7894536469271067e-08 7.319714025553677 0.24391689819276063 AS(ph)TFCGTPDYIAPEILQGLK ddPTM_PC-9_AZD4547_30min_R2 1 ASTFCGTPDYIAPEILQGLK 20 0 Q05655;Q05655-2 Q05655 PRKCD Protein kinase C delta type;Protein kinase C delta type regulatory subunit;Protein kinase C delta type catalytic subunit 1 AS(0.496)T(0.496)FCGT(0.008)PDYIAPEILQGLK 196.36 9.853300000000002e-16 2841900.0 11800.0 13857.0 14981.0 12813.0 12564.0 17210.0 15233.0 13775.0 13955.0 12946.0 True False 15552.154544752675 18336.004261595852 14782.342151588486 9859.160808876644 10819.705470426285 16133.85597939196 16588.707489768793 11646.39026800968 14692.632810302863 12492.764480455717 1.2448929593672573 1.4677299240117414 1.183272299314911 0.7891896804987232 0.8660777594385257 1.291456026777143 1.3278652227632215 0.9322508469786535 1.1760913954064152 1.0 13.608805140797383 -5.517849494128586 24.78454288800883 1.059188639871011 1.3486089128424015 0.329349458646081 0.17162635646454902 227.82793768095743 1122751.8801246434 0.04977795149410838 0.08945942697728884 3.034942769203454e-06 5.517849494128586 0.2894202729713904 AS(ph)TGPPLIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASTGPPLIK 9 0 A0A087WZ32;A0A087X038;A8K727;Q9HB19;E5RHB5 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 AS(0.967)T(0.033)GPPLIK 85.53299999999999 0.025443 0.0 14888.0 15014.0 15485.0 26097.0 29694.0 27967.0 31203.0 24096.0 23314.0 22978.0 True False 17408.244348596407 16504.490695930752 15854.221127189532 24634.869697615544 23875.673860162555 26500.361286910284 28247.225949843036 23463.50553182237 23654.923144245302 27143.72950625209 0.6413357583963073 0.608040641288045 0.5840841113428347 0.9075712934709774 0.8796018194428 0.9762977221242344 1.040653825530378 0.8644171585344584 0.8714691597113359 1.0 14.728331337981935 -5.786784643346109 6.58991846359474 0.9337360371708257 0.6102099199244523 0.8746998469501682 0.05606438991199159 0.05542268614377183 8.268371470268757 0.016819528474713373 0.02596886118739856 1.6338619416413207e-06 5.786784643346109 -0.32352611724637337 AS(ph)TGPPLIK ddPTM_PC-9_Lapatinib_30min_R1 1 ASTGPPLIK 9 0 A0A087WZ32;A0A087X038;A8K727;Q9HB19;E5RHB5 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 AS(0.98)T(0.02)GPPLIK 77.37899999999999 0.023144 4534900.0 11438.0 20094.0 27514.0 17347.0 29180.0 25887.0 26354.0 22625.0 30077.0 30621.0 True False 11274.892022527687 20047.47357757169 25251.905127111393 18622.75624789561 27463.689770087287 24779.87335554439 27718.481168887636 23676.240096623274 26689.411535148975 35913.799050082234 0.31394317284018636 0.5582108857271056 0.7031254224009357 0.5185404145611537 0.7647113504140521 0.6899819571020196 0.7718058769063633 0.659251895451285 0.7431519984262946 1.0 15.132250652457715 -5.062952694553531 0.1427898927040881 1.0544404351199832 2.7391778913729844e-21 0.7055529553100819 0.09357171777221013 15.6455255739044 0.42152805934267823 0.5860176221937783 3.234973972065393 8.650621403784098e-06 5.062952694553531 -1.0544404351199832 down AS(ph)TPDWVSEGPQPGLR ddPTM_PC-9_AZD4547_30min_R2 1 ASTPDWVSEGPQPGLR 16 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 AS(0.705)T(0.295)PDWVSEGPQPGLR 148.18 1.8893e-05 116080000.0 66273.0 63703.0 85793.0 110310.0 110800.0 96544.0 98316.0 122460.0 107520.0 96012.0 True False 87346.43543596541 84293.74896993865 84655.3287638496 84879.73377251094 95417.33254721665 90507.08841803683 107065.93353667123 103536.62085085073 113203.28769356945 92650.64910377853 0.9427503884849006 0.9098020336103715 0.9137046484048554 0.9161267038446396 1.02986145774693 0.9768640510727488 1.1555875168963583 1.117494824400839 1.2218294074418172 1.0 16.499513463255006 -6.913809260283147 1.2903974592323628 1.1364750435176365 0.9216069604782853 0.663192667342279 0.06118678457821405 0.23997740431881925 0.827361353337429 0.030439452421757957 0.023894283936760838 1.2195250899490486e-07 6.913809260283147 -0.21486808303935123 AS(ph)TPDWVSEGPQPGLR ddPTM_PC-9_Lapatinib_30min_R1 1 ASTPDWVSEGPQPGLR 16 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 AS(0.983)T(0.017)PDWVSEGPQPGLR 87.824 0.0041478 2873800.0 7725.8 6056.2 10929.0 8083.2 10632.0 12523.0 12478.0 13059.0 16058.0 10735.0 True False 7615.628675261795 6042.177240991819 10030.459807160001 8677.665492764732 10006.646663316244 11987.420482538811 13124.049784677094 13665.768814223346 14249.378941763547 12590.530446511626 0.6048695650763314 0.47989854491522915 0.7966669752138261 0.6892215963124091 0.7947756217124846 0.9520981291030582 1.042374651364533 1.0854005613408948 1.13175366219074 1.0 13.620051445484128 -6.473674472049009 0.7524471516298251 1.1004030549543071 0.5593078664921881 0.875861524169177 0.07331104011261227 0.21894362991112543 0.2753095638785889 0.04593719261827423 0.062373933080049404 3.3598936265939836e-07 6.473674472049009 -0.541095188462119 AS(ph)TPQPAPAGVPALASQHPPEEEVHYHLPVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASTPQPAPAGVPALASQHPPEEEVHYHLPVAR 32 0 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 AS(0.499)T(0.499)PQPAPAGVPALAS(0.001)QHPPEEEVHYHLPVAR 50.942 0.0047983 3670800.0 3118.7 5458.8 4471.2 5332.8 7124.5 6908.7 6358.3 5033.4 6637.0 3469.9 True False 3646.6343128672497 6000.713588047607 4577.810365120425 5034.020505170874 5728.505368651183 6546.395609928741 5755.995793894399 4901.278583328136 6734.053569029596 4098.965402286716 0.8896474975936314 1.4639580965235643 1.116820933049733 1.2281197841685885 1.3975490901814844 1.5970848659216934 1.4042557643163478 1.1957355337992919 1.6428666524662114 1.0 12.001044097479367 -4.75226635089637 24.984778483023053 1.3462105672543754 0.8896466041258477 0.3224344642313832 0.1949055452015556 428.3165088127842 1166530.326454207 0.04723126168518444 0.5733499563956044 1.769023691104413e-05 4.75226635089637 -0.45656396312852765 AS(ph)TPVLK ddPTM_PC-9_AZD4547_30min_R2 1 ASTPVLK 7 0 A0A669KBK8;Q04724;F6T2C8;A0A669KAE5 A0A669KBK8 TLE1 Transducin-like enhancer protein 1 1 AS(0.694)T(0.306)PVLK 115.49 0.0082036 26342000.0 272570.0 232650.0 309660.0 403240.0 369560.0 321980.0 264760.0 342350.0 313380.0 319910.0 True False 359241.5901917995 307849.56278128555 305553.70607175014 310279.2479958959 318252.973069941 301846.5397004427 288323.12709191756 289447.6739203715 329944.62702205015 308710.0482730257 1.163686093800495 0.99721264177647 0.9897757063013249 1.005083085994928 1.0309122584454247 0.9777671358254174 0.9339609407106898 0.9376036690078244 1.068784864204499 1.0 18.235892916760548 -4.761167668532224 5.752589145046671 0.9901017908433835 1.1710827838019708 0.6464002503715799 0.03773471798528989 0.09085191646431716 10.508040321437482 0.009701930348408877 0.06519981430991338 1.7331347553977962e-05 4.761167668532224 0.18098099295858738 AS(ph)TPVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASTPVLK 7 0 A0A669KBK8;Q04724;F6T2C8;A0A669KAE5 A0A669KBK8 TLE1 Transducin-like enhancer protein 1 1 AS(0.504)T(0.496)PVLK;AS(0.739)T(0.261)PVLK 86.794 0.018374 8339100.0 189433.0 159671.0 164265.0 193154.0 220120.0 173600.0 178154.0 166775.0 156557.0 136162.0 True False 221500.2654277049 175522.0816511231 168181.70057848128 182332.20759371747 176989.06614464178 164496.11039466618 161277.96339673558 162397.3329627191 158846.3499482551 160847.09274220074 1.3770859121632781 1.0912356490797308 1.045599878190128 1.133574778911001 1.1003560159356611 1.0226862518324402 1.0026787593557902 1.0096379747627957 0.9875612125787543 1.0 17.295330334429238 -2.0089286757003024 1.1013481271357761 1.0346694984010563 199.99999999992684 0.8376636317297959 0.044489339983954664 386.82874981305844 1.0854321502637059 0.015350200185980333 193665.51424887756 0.00979650860522652 2.0089286757003024 198.96533050152578 AS(ph)TPVLK ddPTM_PC-9_Lapatinib_30min_R1 2 ASTPVLK 7 0 A0A669KBK8;Q04724;F6T2C8;A0A669KAE5 A0A669KBK8 TLE1 Transducin-like enhancer protein 1 1 AS(0.5)T(0.5)PVLK;AS(0.5)T(0.5)PVLK 136.27 0.0036071 53509000.0 650340.0 566910.0 695680.0 561880.0 550890.0 563150.0 460750.0 442920.0 542370.0 383610.0 True False 641066.0323422505 565597.3547258463 638483.8758024595 603202.5295767345 518487.73329141154 539065.3872667685 484605.38053293584 463499.6801589548 481282.57919070194 449916.47737180407 1.4248556445121776 1.2571163386364383 1.4191164536408527 1.340698907273532 1.1524088566841735 1.1981454656111497 1.0771007618208777 1.030190498615426 1.0697153880696337 1.0 18.77929767840041 -6.690302280748409 0.8691862687730431 1.027550435863643 1.3750773071617968 0.8579256304163531 0.05650375296011929 0.2111103335847127 0.34928846388968704 0.0344208315779916 0.03472114950752177 2.040317334085798e-07 6.690302280748409 0.34752687129815385 AS(ph)TPYIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASTPYIEK 8 0 C9J618;C9J5A2;C9J347;C9J7P5;C9IZN7;Q969Z0-2;Q969Z0 C9J618 TBRG4 Protein TBRG4 1 AS(0.634)T(0.366)PYIEK 108.57 0.0037919000000000004 9947700.0 142730.0 147170.0 149840.0 145550.0 224110.0 138390.0 130280.0 151140.0 149890.0 137320.0 True False 166891.36995400098 161780.0649873539 153412.7538713641 137395.3053794666 180197.25428709594 131132.58477832834 117938.93525448025 147172.73514606748 152081.85768597986 162215.02897547834 1.0288280377475354 0.9973185962430756 0.9457369939166065 0.8469949193193209 1.1108542496043072 0.8083873954622992 0.7270530726983921 0.9072694193354627 0.9375324755449738 1.0 17.30754796368342 -6.791987145454586 24.996800585524657 0.8609405980276935 0.9766251354302661 0.24759430325260723 0.09325603006993792 287.32688693132525 235113.51084714534 0.033371752546474946 0.029434404139451847 1.6144063404234804e-07 6.791987145454586 0.11568453740257256 AS(ph)VSPMDEPVPDSESPIEK ddPTM_PC-9_Lapatinib_30min_R1 1 ASVSPMDEPVPDSESPIEK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 AS(0.552)VS(0.448)PMDEPVPDSESPIEK 101.75 0.00021453 3397200.0 25114.0 23639.0 29990.0 27373.0 24744.0 25783.0 21100.0 27524.0 27499.0 22312.0 True False 24755.869754656454 23584.265347875826 27524.337964747763 29386.101733651147 23288.60656857575 24680.321193108546 22192.45475690708 28802.865521302043 24401.77304269247 26168.599471128786 0.9460143169667539 0.9012429333062246 1.051807835383576 1.1229527879805778 0.8899447062220328 0.9431273240410812 0.8480566482509506 1.1006651522592785 0.9324829580434515 1.0 14.675549093766305 -7.781333464721625 24.999990107647868 1.0124304122633632 0.9622505275505406 0.07624480068494188 0.08414086634256301 804.6995283837728 1011215.4727536765 0.04789542555523423 0.023057008298892765 1.654499100099683e-08 7.781333464721625 -0.05017988471282253 AS(ph)VSQTSPQSASSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASVSQTSPQSASSPR 15 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 AS(0.583)VS(0.416)QT(0.001)SPQSASSPR 138.98 5.6766000000000005e-05 2658400.0 3871.4 4418.0 3948.7 4785.8 6482.1 4950.5 5178.1 4338.6 4277.0 4258.1 True False 4526.751556364598 4856.589842455182 4042.8519835281436 4517.667141772948 5211.979037144194 4690.88706514282 4687.592881802461 4224.716347126684 4339.543033710953 5030.059822898947 0.8999399044434666 0.9655133365106204 0.8037383502127314 0.8981338792844228 1.0361664116631526 0.9325708302290819 0.931915930793222 0.8398938573044399 0.8627219529190346 1.0 12.296359842881044 -4.439403168403573 21.16787990225138 0.9152892944170181 0.0007985668920987813 0.004414262762166721 0.06787521745188962 3944.644848595298 905538.2032063267 0.01692447757296663 16375.391801041716 3.635773598049908e-05 4.439403168403573 -0.9144907275249193 AS(ph)WESLDEEWR ddPTM_PC-9_AZD4547_30min_R2 1 ASWESLDEEWR 11 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 AS(0.998)WES(0.002)LDEEWR 83.314 0.037863 0.0 2208.7 2911.2 3553.5 5396.9 4028.1 3408.8 3332.5 4822.0 2967.0 3891.8 True False 2911.0206561860377 3852.1884683811672 3506.378268184345 4152.7280862738135 3468.8678450671855 3195.6471971267456 3629.086044092074 4076.870698536678 3123.8295627494476 3755.549266571729 0.7751251413733621 1.0257323749337086 0.9336525816329283 1.1057578509853103 0.9236645824203921 0.8509134004901252 0.9663263044888512 1.0855591044497916 0.8317903297274677 1.0 11.87480820870216 AS(ph)WESLDEEWR ddPTM_PC-9_Lapatinib_30min_R1 1 ASWESLDEEWR 11 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 AS(1)WESLDEEWR 132.56 0.00010194 615670.0 2010.9 1369.5 1552.8 1338.1 4870.6 2157.4 1374.5 2969.5 2964.9 1323.3 True False 1982.2241972461031 1366.3290068918288 1425.1347779813393 1436.508337770746 4584.120883968034 2065.133031145034 1445.664884519849 3107.47381069272 2630.961740218878 1552.0306418135867 1.2771810967145754 0.8803492470324162 0.9182388153857798 0.9255669953089006 2.9536278218137326 1.330600682427168 0.9314667156510218 2.002198749801459 1.6951738382848762 1.0 10.599941325664005 AS(ph)Y(ph)AFLREALRS(ph)SVGSPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASYAFLREALRSSVGSPLR 19 2 E9PP40;Q15048 E9PP40 LRRC14 Leucine-rich repeat-containing protein 14 3 AS(1)Y(1)AFLREALRS(0.416)S(0.357)VGS(0.227)PLR 54.261 0.013918999999999999 10311000.0 31057.0 36326.0 26453.0 35587.0 38564.0 36428.0 44003.0 35621.0 42455.0 34074.0 True False 36314.33669628954 39932.20520982953 27083.73984356117 33593.17576461069 31007.66103399034 34517.651552171046 39834.71728586816 34685.986493569275 43075.82405803097 40251.34647036441 0.9021893645974415 0.9920712898195877 0.6728654372718172 0.8345851433651819 0.7703509013498502 0.8575527175863576 0.9896493106186397 0.8617348122529837 1.070171008807025 1.0 15.296749423984815 -7.621283470158893 1.1788318755599525 1.0092292413790536 0.8341272201051529 0.3653073369030636 0.09124731649235836 0.58308495140118 1.4937993610169695 0.07574982373407407 0.03250851788363791 2.391754115024788e-08 7.621283470158893 -0.17510202127390062 AS(ph)Y(ph)HGLY(ph)Y(ph)IIT(ph)LVVVNGNVVTK ddPTM_PC-9_AZD4547_30min_R2 1 ASYHGLYYIITLVVVNGNVVTK 22 0 A0A6I8PRZ5;A0A6I8PL17;Q16827-5;Q16827-2;Q16827 A0A6I8PRZ5 PTPRO Receptor-type tyrosine-protein phosphatase O 5 AS(1)Y(1)HGLY(0.999)Y(0.999)IIT(0.994)LVVVNGNVVT(0.009)K 41.912 0.018893 17695000.0 775.51 1610.1 3110.5 4663.6 3969.7 1607.7 3436.5 4086.0 2969.9 1585.8 True False 1022.1060483899275 2130.533337778414 3069.252737635405 3588.4790719017474 3418.575677009805 1507.1702648499963 3742.3418426173757 3454.6025869392092 3126.8828508289835 1530.2816246799532 0.6679202258628004 1.3922491804238968 2.005678358895093 2.344979521434331 2.233951987579263 0.9848973159860098 2.4455249166309883 2.257494654071739 2.0433381675630766 1.0 10.579581467737128 -4.9214270878354265 2.4073668056793767 1.9709335732257727 0.5586242197487423 0.3765234016999649 0.49475956620966677 0.4047118624801673 3.6622133016281446 0.12881631500664195 1.065239490327062 1.1983202880581291e-05 4.9214270878354265 -1.4123093534770303 ASAAEAVRS(ph)S(ph)T(ph)S(ph)RPR ddPTM_PC-9_Lapatinib_30min_R1 1 ASAAEAVRSSTSRPR 15 2 Q7Z5J1-4;Q7Z5J1-3;Q7Z5J1 Q7Z5J1-4 HSD11B1L Hydroxysteroid 11-beta-dehydrogenase 1-like protein 4 AS(0.001)AAEAVRS(1)S(1)T(1)S(1)RPR 56.746 0.04487 2627000.0 1315.5 810.92 2158.2 1907.6 2144.4 1918.2 908.65 1348.3 2824.9 1220.4 True False 1296.7407287668464 809.0423645627759 1980.7611268929193 2047.891267567054 2018.270608052612 1836.1630575425993 955.6954509414037 1410.946940211144 2506.730014484235 1431.3445139192177 0.9059598972550587 0.5652324487187972 1.3838465216660687 1.430746579633471 1.4100522888974578 1.2828239740235095 0.6676907213096995 0.9857493611707623 1.7513114348833214 1.0 10.483155244429287 -5.262779002709258 24.992812777746842 1.232633059715969 0.7355961612934037 0.32091136684005206 0.2928166120078118 139.00465784109522 2593412.9390519727 0.07970449192194806 0.1820111550034299 5.4603564887421525e-06 5.262779002709258 -0.49703689842256527 ASAAFSSVGS(ph)VITK ddPTM_PC-9_Lapatinib_30min_R1 1 ASAAFSSVGSVITK 14 0 H0YC42;P55327-2;P55327;P55327-3;P55327-4;P55327-7;P55327-5;P55327-6 H0YC42 TPD52 Tumor protein D52 1 ASAAFS(0.045)S(0.112)VGS(0.842)VITK 125.33 0.00074945 0.0 11477.0 10729.0 8900.5 6818.1 9814.1 7410.3 11443.0 10214.0 7196.5 9116.1 True False 11313.335875375975 10704.157659687793 8168.735246923562 7319.525818514849 9236.853933262975 7093.378743253008 12035.462548970994 10688.57972804022 6385.954387495412 10691.805738560292 1.0581314468307368 1.0011552698795259 0.7640183002449057 0.6845921070298516 0.863918982361418 0.6634406681811046 1.125671644553433 0.9996982726212059 0.5972755719330265 1.0 13.384217909882272 -5.123021970156328 5.055612088199144 0.8373833502876282 1.044652383791522 0.19203859523696531 0.15928975314023597 0.35769923618067856 12.935753538641851 0.041515598769797865 0.11883426910537029 7.533174538300648e-06 5.123021970156328 0.2072690335038938 ASAELIEEEVAK ddPTM_PC-9_Lapatinib_30min_R1 2 ASAELIEEEVAK 12 0 P12081-3;P12081-2;P12081-4;P12081;A0A2R8YFR1;D6RF05;A0A2R8YCI2;E7ETE2;B4E1C5;B4DDD8 P12081-3 HARS Histidine--tRNA ligase, cytoplasmic 0 ; 175.15 2.6011000000000003e-25 1612400.0 22225.0 21225.7 23790.0 21220.0 20853.6 20463.9 22953.0 21078.6 23633.0 19878.1 False True 21908.06742443416 21176.553195753124 21834.078032055673 22780.589587844872 19627.032247755054 19588.706700680843 24141.394030108462 22057.98870721252 20971.202673477244 23314.003099096688 0.9396956554956879 0.9083190521053683 0.9365220524012732 0.9771204666575478 0.8418559508776728 0.8402120655735786 1.0354890117966842 0.9461261806243462 0.8995110185213017 1.0 14.508909121269372 -10.649998141040626 5.108366972708176 1.000002596128719 0.925299974770433 0.1413924070776026 0.05545283416949692 1.7033821270089518e-06 2.9110892444808406e-07 0.055781740689996875 0.013528589229430517 2.238730721237993e-11 10.649998141040626 -0.07470262135828587 ASAGPAPGPVVTAEGLHPSLPS(ph)PTGNSTPLGSSK ddPTM_PC-9_AZD4547_30min_R2 1 ASAGPAPGPVVTAEGLHPSLPSPTGNSTPLGSSK 34 0 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 ASAGPAPGPVVTAEGLHPS(0.002)LPS(0.905)PT(0.082)GNS(0.005)T(0.007)PLGSSK 121.3 2.725e-24 13154000.0 3102.9 3333.8 33024.0 92472.0 53945.0 58131.0 21439.0 63705.0 32450.0 54782.0 True False 4089.5576556706 4411.385653987751 32586.080182501715 71154.00907815811 46455.66790848022 54496.059380478415 23347.02946715377 53860.85604526729 34165.24075201199 52864.09885434305 0.07735982915245745 0.08344766579947732 0.6164122890335547 1.3459797976356207 0.8787753676929208 1.0308708662684656 0.44164243736532915 1.0188550871484752 0.646284368643979 1.0 15.690000669220163 -5.380995802992022 3.667228169169173 0.8986561836113658 0.07685188645733237 0.668378914761161 0.22983336503161012 0.13410181914896863 3.202712751416652 0.06171638060352252 0.14227558209887975 4.159146298602767e-06 5.380995802992022 -0.8218042971540334 ASAGPAPGPVVTAEGLHPSLPS(ph)PTGNSTPLGSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASAGPAPGPVVTAEGLHPSLPSPTGNSTPLGSSK 34 0 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 ASAGPAPGPVVTAEGLHPS(0.051)LPS(0.802)PT(0.074)GNS(0.045)T(0.024)PLGS(0.003)S(0.001)K 83.601 5.7662e-07 0.0 1423.8 3792.9 4804.4 6183.6 10424.0 12105.0 10688.0 7802.3 10485.0 8242.3 True False 1664.8212186681606 4169.434045597161 4918.955116788466 5837.152939501686 8381.492029310113 11470.19249036539 9675.55526558095 7597.4978922201935 10638.323289328817 9736.563743989103 0.17098652691468721 0.4282243874971982 0.5052044279816067 0.5995085219983559 0.8608264937909386 1.17805344800896 0.9937340852468801 0.7803058750486311 1.0926157902367164 1.0 13.24919698672274 -5.910946924206804 1.1495092746472138 1.00101172871271 0.27734626505554005 0.859072347727462 0.11606540348249182 0.1937084154556456 0.5150869555164921 0.04655378536061933 0.1033336372410103 1.2275892475517704e-06 5.910946924206804 -0.72366546365717 down ASAGPAPGPVVTAEGLHPSLPS(ph)PTGNSTPLGSSK ddPTM_PC-9_Lapatinib_30min_R1 1 ASAGPAPGPVVTAEGLHPSLPSPTGNSTPLGSSK 34 0 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 ASAGPAPGPVVTAEGLHPS(0.03)LPS(0.388)PT(0.106)GNS(0.154)T(0.186)PLGS(0.061)S(0.074)K 60.675 0.0012132 0.0 5306.8 3372.1 5210.9 3218.9 7229.0 8219.6 4705.9 7464.9 9794.5 4067.3 True False 5231.124058852067 3364.2921096312043 4782.4799166556895 3455.6286439356213 6803.80443276083 7868.066868823454 4949.548475854455 7811.746505957265 8691.340269342574 4770.327385663416 1.096596446309642 0.7052539244459691 1.0025475255700051 0.7244007307173619 1.426276203433911 1.6493767057728326 1.03756997700612 1.637570312141349 1.8219588650169463 1.0 12.219872565875098 -6.273649624316117 23.031385905572364 1.4521387807888424 0.8781569758636576 0.5035099734906288 0.265282016501821 207.19000209925105 390807.83647841256 0.08012834660789277 0.09166672281635684 5.32537721370125e-07 6.273649624316117 -0.5739818049251848 ASAGPAPGPVVTAEGLHPSLPSPT(ph)GNSTPLGSSK ddPTM_PC-9_AZD4547_30min_R2 1 ASAGPAPGPVVTAEGLHPSLPSPTGNSTPLGSSK 34 0 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 ASAGPAPGPVVTAEGLHPS(0.002)LPS(0.418)PT(0.419)GNS(0.11)T(0.04)PLGS(0.005)S(0.005)K 102.08 5.1205e-16 10533000.0 3220.8 1340.2 26778.0 71225.0 49521.0 43626.0 18662.0 56093.0 27001.0 42090.0 True False 4244.947403198256 1773.3934409605808 26422.906223565613 54805.17666528043 42645.86394468164 40898.05932347202 20322.881846915596 47425.115738908724 28428.217736365983 40616.44191119895 0.10451302978432044 0.0436619594802964 0.6505470440107697 1.3493347542628864 1.0499655296719412 1.0069335815502694 0.5003609595185166 1.1676334387585157 0.6999189588915623 1.0 15.309776241490184 -5.400927366966838 3.6917572961700325 0.9628754702420451 0.07519583810625867 0.7127835684395902 0.2236723642155227 0.12207309300447076 2.938249861652405 0.060853701790919326 0.13819338394043873 3.972579828245656e-06 5.400927366966838 -0.8876796321357865 down ASAGRLT(ph)PESQSK ddPTM_PC-9_AZD4547_30min_R2 1 ASAGRLTPESQSK 13 1 A0A0D9SGJ6;J3KQV8;O43426;H7BZ56;H7BZC2;J3KPK1;C9JFZ1;O43426-4;O43426-2 A0A0D9SGJ6 SYNJ1 Synaptojanin-1 1 ASAGRLT(0.997)PES(0.003)QSK 115.09 0.0030363000000000005 5622100.0 11980.0 12250.0 16591.0 22001.0 15247.0 15485.0 14461.0 14615.0 13657.0 14538.0 True False 15789.390800520083 16209.572938193623 16370.992499633185 16929.00936206158 13130.217232377392 14516.720502085098 15748.000985330964 12356.587569289406 14378.88113868191 14029.0290450228 1.1254799423287116 1.1554308488615208 1.1669369595782013 1.2067128314961777 0.9359320014406637 1.0347630228362326 1.1225296444102821 0.8807870829573383 1.024937726804638 1.0 13.776127542434267 -6.2565920709257385 24.997708673652873 1.001746408337602 1.1632892577557088 0.6253456381248557 0.06210675502546629 283.24211890869736 1460686.3086786435 0.01881289357764971 0.023533345810531046 5.538701103955843e-07 6.2565920709257385 0.16154284941810682 ASAGTPSLSAGVS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 ASAGTPSLSAGVSPK 15 0 Q8TEK3-1;Q8TEK3 Q8TEK3-1 DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 1 ASAGTPSLSAGVS(1)PK;ASAGTPSLS(0.001)AGVS(0.999)PK 158.14 0.00024211 34374000.0 66678.0 62911.0 68695.0 82618.0 74241.0 64558.0 72516.0 65875.0 68706.0 78151.0 True False 87880.2170114421 83245.75045834287 67784.05941548437 63571.69653537587 63933.91864294148 60521.17805447914 78969.78351789377 55695.532406906554 72337.65889392105 75414.95727731296 1.1652889583732358 1.1038360752792686 0.8988145304681596 0.8429587290172755 0.8477617829556827 0.8025089483500336 1.0471368859563115 0.7385210363788326 0.9591951186542984 1.0 16.202563065507178 -5.217007508666276 3.2969228966536566 0.8799386325673223 1.1536899178902404 0.5507927419292015 0.08794041659189876 0.16385699527880127 3.5889754625012253 0.021885000961286673 0.06689485937625136 6.067258396066539e-06 5.217007508666276 0.27375128532291815 ASAGTPSLSAGVS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ASAGTPSLSAGVSPK 15 0 Q8TEK3-1;Q8TEK3 Q8TEK3-1 DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 1 ASAGTPSLSAGVS(1)PK;ASAGTPS(0.006)LS(0.006)AGVS(0.987)PK;ASAGTPSLSAGVS(1)PK;ASAGTPSLSAGVS(1)PK 165.89 4.1928e-05 37431300.0 94063.0 87972.0 86542.0 124806.0 104816.0 85887.0 111609.0 110821.0 84209.0 74289.0 True False 109986.00807106552 96705.27877330637 88605.48949236283 117813.5244465113 84278.05722795159 81382.93452457763 101036.58754081432 107912.0661745555 85440.39731722376 87757.00762859966 1.2533017139388138 1.10196645699882 1.0096685368689196 1.34249705670361 0.9603570074384089 0.9273667906841352 1.1513221595751733 1.2296689357419177 0.9736019906104806 1.0 16.421226712571986 -4.770404303236481 4.777105192803768 1.0837692563364194 1.2642046596576486 0.1502434135550632 0.12536250284756562 0.36834128500682833 20.379025342435643 0.03148646092643706 0.22251775293283713 1.6966634207580024e-05 4.770404303236481 0.1804354033212292 ASALYESS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 ASALYESSR 9 0 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 ASALYES(0.2)S(0.8)R 69.346 0.023017 2085300.0 2630.0 1233.7 2461.2 976.61 597.11 2867.6 1479.2 919.99 875.75 651.27 True False 2592.4957177170672 1230.8434434483022 2258.849636506744 1048.4331572754559 561.9891637634278 2744.9594327020923 1555.7857382188142 962.7360939886162 777.1138129436679 763.8411517372738 3.394024676231069 1.6113866615445926 2.957224327818992 1.3725800906260528 0.7357408834091282 3.593626013025064 2.036792250169225 1.2603878329924716 1.0173762060033122 1.0 9.577128836637488 -1.5228787635422731 0.11239320981699512 0.5229190911235534 7.161847177414938 0.2598806425404826 0.8582333059519526 171.41876912759378 1.345251606023648 7.684814566902898 176.79517994121636 0.029999998738510208 1.5228787635422731 6.638928086291385 ASAPS(ph)PNAQVACDHCLK ddPTM_PC-9_AZD4547_30min_R2 6 ASAPSPNAQVACDHCLK 17 0 A0A3B3IUA7;Q14258 A0A3B3IUA7 TRIM25 E3 ubiquitin/ISG15 ligase TRIM25 1 AS(0.015)APS(0.985)PNAQVACDHCLK;AS(0.006)APS(0.994)PNAQVACDHCLK;ASAPS(1)PNAQVACDHCLK;AS(0.059)APS(0.941)PNAQVACDHCLK;ASAPS(1)PNAQVACDHCLK;AS(0.04)APS(0.96)PNAQVACDHCLK 184.57 2.0181e-08 559391100.0 508115.0 443879.0 676452.0 740323.0 660809.0 663397.0 598926.0 715858.0 553225.0 620743.0 True False 669685.0005514397 587354.2062230568 667481.8044941147 569652.9702263307 569067.076743627 621914.6807182267 652229.2537265975 605238.5948803548 582467.3440687776 599010.9765094657 1.117984522510427 0.9805399721481987 1.114306466274858 0.9509892014763921 0.9500111000630961 1.038235867299502 1.0888435760013002 1.0103965012580878 0.9723817541089305 1.0 19.192222914196584 -4.749481707189643 24.94609174733295 1.0146842522798136 1.1179847623188748 0.26889468343179523 0.052352549855360586 804.4718957835508 1678183.0613769817 0.013362135146857829 0.21833069885344816 1.7804028991841474e-05 4.749481707189643 0.10330051003906116 ASAPS(ph)PNAQVACDHCLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ASAPSPNAQVACDHCLK 17 0 A0A3B3IUA7;Q14258 A0A3B3IUA7 TRIM25 E3 ubiquitin/ISG15 ligase TRIM25 1 AS(0.011)APS(0.989)PNAQVACDHCLK;ASAPS(1)PNAQVACDHCLK;AS(0.047)APS(0.953)PNAQVACDHCLK;AS(0.032)APS(0.968)PNAQVACDHCLK;AS(0.051)APS(0.949)PNAQVACDHCLK 153.6 1.2709000000000001e-05 460043400.0 480321.0 490925.0 518656.0 502655.0 574735.0 526022.0 559548.0 429550.0 502066.0 401005.0 True False 561629.858527819 539660.7895897027 531022.7260538324 474492.86997949844 462119.8025197193 498436.48031119205 506543.5626632936 418274.7676458463 509407.7654344462 473704.0321461666 1.1856134219151462 1.13923621706303 1.1210010682154792 1.0016652546311626 0.9755454274392309 1.0522107613333425 1.0693249968093876 0.8829875602933078 1.0753713940886676 1.0 18.853626426559877 -5.658530301129042 3.2342312762968763 1.005742697693469 1.1577805095128433 0.5982088450603738 0.05329384794872651 0.16470736781301623 3.393363194163484 0.014903427157542327 0.027783267580015474 2.1951777842054784e-06 5.658530301129042 0.15203781181937437 ASAPS(ph)PNAQVACDHCLK ddPTM_PC-9_Lapatinib_30min_R1 6 ASAPSPNAQVACDHCLK 17 0 A0A3B3IUA7;Q14258 A0A3B3IUA7 TRIM25 E3 ubiquitin/ISG15 ligase TRIM25 1 AS(0.012)APS(0.988)PNAQVACDHCLK;AS(0.009)APS(0.991)PNAQVACDHCLK;AS(0.011)APS(0.989)PNAQVACDHCLK;AS(0.071)APS(0.929)PNAQVACDHCLK;AS(0.047)APS(0.953)PNAQVACDHCLK;AS(0.018)APS(0.982)PNAQVACDHCLK 177.32 2.3519e-06 635950200.0 822865.0 804563.0 871365.0 722660.0 708015.0 744288.0 681820.0 575448.0 780864.0 531015.0 True False 811130.7942050399 802700.0838057016 799724.733266171 775806.8271230891 666370.949711047 712456.5372600702 717121.3034291186 602185.4148562052 692914.8734575441 622800.2352169878 1.302393204656444 1.2888564236428643 1.2840790482160649 1.2456752314051276 1.06995937385746 1.1439567568754139 1.151446744684142 0.9668997871306195 1.1125796592162942 1.0 19.24840996372582 -6.250642483440137 0.5306875961235831 1.023938100432399 1.3518414127738076 0.7762005052316931 0.05457263588031618 0.5546355966470946 0.30926154054465077 0.043120679759100077 0.09355518184874867 5.615100277851757e-07 6.250642483440137 0.32790331234140857 ASAS(ph)PDRIPSLPQETVDQEPK ddPTM_PC-9_AZD4547_30min_R2 2 ASASPDRIPSLPQETVDQEPK 21 1 A0A494C1R1;A0A2R8Y5U1;Q76L82;Q8IXJ9 A0A494C1R1 ASXH1;ASXL1 Putative Polycomb group protein ASXL1 1 AS(0.205)AS(0.795)PDRIPSLPQETVDQEPK;AS(0.353)AS(0.646)PDRIPS(0.001)LPQETVDQEPK 80.102 0.00042931 32048000.0 60595.0 60909.0 69279.0 80461.0 74050.0 73389.0 72863.0 74211.0 64965.0 65588.0 True False 79862.9495457025 80596.64310958661 68360.31519390554 61911.95956005807 63769.43569604148 68799.97422844844 79347.6658456656 62743.39514913006 68398.91727132401 63291.78408343341 1.2618217467282073 1.2734139869298255 1.0800819756287896 0.9781989946506104 1.0075468185883085 1.0870285175995977 1.2536803472164217 0.9913355431159842 1.0806918822379568 1.0 15.949730614884304 -5.2816342574523585 5.625826401904871 1.0618962503536868 1.2690675789542818 0.5493754442178028 0.07534748923707336 0.12461126039046462 13.953189452003736 0.020842346469531522 0.04770366362449396 5.228363119929942e-06 5.2816342574523585 0.20717132860059495 ASAS(ph)PDRIPSLPQETVDQEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASASPDRIPSLPQETVDQEPK 21 1 A0A494C1R1;A0A2R8Y5U1;Q76L82;Q8IXJ9 A0A494C1R1 ASXH1;ASXL1 Putative Polycomb group protein ASXL1 1 AS(0.092)AS(0.907)PDRIPS(0.001)LPQETVDQEPK;AS(0.285)AS(0.715)PDRIPSLPQETVDQEPK 90.755 0.00019769 21867000.0 48557.0 51231.0 48331.0 64191.0 62182.0 49518.0 68139.0 49241.0 49389.0 42623.0 True False 56776.74105553438 56316.87510611621 49483.39433633818 60594.586380029876 49997.88347722193 46921.188908543 61684.3806363605 47948.47592515215 50111.22069019178 50350.21249651765 1.127636572724717 1.1185032259796566 0.9827842204193394 1.2034623763349708 0.993002432326972 0.9318965418822849 1.2251066594927829 0.9522993756673497 0.9952534101749343 1.0 15.61971024650098 -1.5228787452804458 0.18197784448752458 0.9872202476947876 1.5850949518887387 0.1384856459090218 0.093557952685301 121.86699480121744 1.383554664881989 0.20803958593647326 20.20654555780605 0.029999999999992526 1.5228787452804458 0.5978747041939512 ASAS(ph)PDRIPSLPQETVDQEPK ddPTM_PC-9_Lapatinib_30min_R1 2 ASASPDRIPSLPQETVDQEPK 21 1 A0A494C1R1;A0A2R8Y5U1;Q76L82;Q8IXJ9 A0A494C1R1 ASXH1;ASXL1 Putative Polycomb group protein ASXL1 1 AS(0.225)AS(0.775)PDRIPSLPQETVDQEPK;AS(0.223)AS(0.772)PDRIPS(0.005)LPQETVDQEPK 136.85 4.1537e-05 32205000.0 45671.0 43730.0 48364.0 48215.0 50689.0 49098.0 53275.0 45483.0 55578.0 41176.0 True False 45019.72316496437 43628.74587176317 44387.69861043885 51760.89194052503 47707.57267840831 46998.19299302811 56033.31882342301 47596.30622385484 49318.22037771418 48293.21673642875 0.9322162864128473 0.9034135396255959 0.9191290539351487 1.0718046019386511 0.9878731611270227 0.9731841481906552 1.1602730695956252 0.985569184252574 1.0212245882662905 1.0 15.559532941944527 -5.746640110441903 24.64702057288132 1.0294452373889533 0.9167689432858536 0.4853163008725817 0.05204426519144287 170.41464972072816 283809.3336042449 0.014139228149672231 0.024352872788783862 1.7920903017041313e-06 5.746640110441903 -0.11267629410309976 ASAS(ph)PGENDSGTGGEEPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASASPGENDSGTGGEEPQR 19 0 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 AS(0.06)AS(0.94)PGENDSGTGGEEPQR 178.23 8.9492e-37 0.0 3434.4 2956.9 4637.7 3297.3 4984.7 4109.0 3249.5 3417.6 2736.7 2431.1 True False 4015.7760875080276 3250.4414905286844 4748.280356575191 3112.5629709908335 4007.9838179683534 3893.5168065189073 2941.683835657309 3327.8916212465188 2776.7190601722614 2871.839185422987 1.3983290247906246 1.1318326969794912 1.6533935398182218 1.0838221676163913 1.3956156870873067 1.3557572534986633 1.0243205297110098 1.158801522779682 0.9668783246173599 1.0 11.48775924939113 -7.261017463527199 24.999321639693832 1.050733543916929 1.3327688792042864 0.4753264555389827 0.15359304691123774 35.00682250924092 2074317.9263217628 0.05783777574154354 0.0420089847091409 5.4825491845795244e-08 7.261017463527199 0.28203533528735747 ASAS(ph)PGENDSGTGGEEPQR ddPTM_PC-9_Lapatinib_30min_R1 1 ASASPGENDSGTGGEEPQR 19 0 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 ASAS(1)PGENDSGTGGEEPQR 136.33 2.9570999999999996e-09 0.0 3915.9 5377.2 3118.8 3089.9 3177.3 4210.8 4420.9 4432.5 5545.2 2956.7 True False 3860.058547911889 5364.749423774182 2862.3843029161503 3317.1415536042364 2990.417460812145 4030.7138998542223 4649.792570370168 4638.450131636802 4920.641182455296 3467.761655444896 1.1131268326504011 1.5470352223748527 0.8254270585239865 0.9565656129785726 0.8623480382847966 1.1623387938226402 1.3408627905753872 1.3375919663780103 1.4189675275776712 1.0 11.759789027995664 -7.03724550473016 6.053867941468223 1.2972982050422925 1.0635667895466352 0.17962211089937308 0.21255298687529875 0.34175615788217834 35.83570563560031 0.08463783590442864 0.06709624997578324 9.17813613873062e-08 7.03724550473016 -0.23373141549565735 ASAS(ph)PSTSSTSSRPK ddPTM_PC-9_AZD4547_30min_R2 2 ASASPSTSSTSSRPK 15 1 J3KP75;F6TH74;O75167-5;O75167-2;O75167;O75167-4;F5H858 J3KP75 PHACTR2 Phosphatase and actin regulator;Phosphatase and actin regulator 2 1 AS(0.308)AS(0.688)PS(0.004)TSSTSSRPK;ASAS(0.965)PS(0.027)T(0.004)S(0.001)S(0.001)T(0.001)SSRPK 122.12 0.00026621 6871980.0 21430.9 23789.2 35316.6 44844.0 42254.3 35833.2 26474.9 44707.6 28930.4 31562.2 True False 28245.480409588137 31478.59367683886 34848.2788085435 34505.90863289348 36388.01980730922 33592.54433938105 28831.114811322775 37799.06769844429 30459.60188141782 30457.216984786017 0.9273821841206737 1.0335348003910876 1.1441714725922236 1.1329304529080861 1.1947256975411034 1.1029420171961604 0.9466102837210796 1.2410545493150498 1.0000783031697542 1.0 14.894496501752897 -4.897087093259833 3.050426374590413 1.1035291663302076 0.9195781855540268 0.25384652538571717 0.08723615442523489 0.3842499147671312 6.082079218456921 0.021642294164314818 0.1503264158845203 1.2673976768950843e-05 4.897087093259833 -0.18395098077618077 ASAS(ph)PSTSSTSSRPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASASPSTSSTSSRPK 15 1 J3KP75;F6TH74;O75167-5;O75167-2;O75167;O75167-4;F5H858 J3KP75 PHACTR2 Phosphatase and actin regulator;Phosphatase and actin regulator 2 1 ASAS(0.544)PS(0.296)T(0.088)S(0.02)S(0.02)T(0.02)S(0.005)S(0.006)RPK;AS(0.201)AS(0.77)PS(0.011)T(0.003)S(0.003)S(0.003)T(0.004)S(0.004)S(0.001)RPK 90.476 0.020309 10402000.0 8487.1 9584.0 12588.7 10744.599999999999 15506.0 13522.5 13595.6 9141.5 7063.700000000001 7805.57 True False 9923.798402134113 10535.436181550578 12888.862350910607 10142.614896463192 12467.71061075236 12813.356294999254 12307.726344379907 8901.545311219876 7166.993249292509 9220.658052141875 1.0762570682066346 1.1425904877909763 1.3978245671865732 1.0999881829591496 1.3521497641761289 1.389635774642226 1.334799129821427 0.9653915437360925 0.7772756791070549 1.0 13.170654000032975 -7.86297416867201 5.012753283119797 0.8851055562184329 1.2595023518902801 0.6241474362537707 0.12218779047944645 0.13506491847431384 5.417502661923707 0.07150579098587422 0.03336931508693273 1.3709633070343718e-08 7.86297416867201 0.37439679567184725 ASAS(ph)PSTSSTSSRPK ddPTM_PC-9_Lapatinib_30min_R1 3 ASASPSTSSTSSRPK 15 1 J3KP75;F6TH74;O75167-5;O75167-2;O75167;O75167-4;F5H858 J3KP75 PHACTR2 Phosphatase and actin regulator;Phosphatase and actin regulator 2 1 AS(0.381)AS(0.528)PS(0.087)T(0.003)SSTSSRPK;AS(0.035)AS(0.951)PS(0.01)T(0.003)SSTSSRPK;AS(0.001)AS(0.911)PS(0.087)T(0.001)SSTSSRPK 91.81200000000001 0.018282 14147600.0 62466.0 51677.4 56380.9 45240.6 45886.8 43078.7 29174.5 33981.4 46440.2 32654.7 True False 61575.22338513858 51557.744155349996 51745.480038567766 48567.744642217476 43187.828640919855 41236.32442235444 30685.012858075155 35560.299899199745 41209.615639014 38299.02138534733 1.6077492624575624 1.3461895967680069 1.351091442204966 1.2681197295761404 1.1276483596377977 1.0766939449301667 0.8011957420357171 0.9284910844433382 1.0759965698439549 1.0 15.225019908500103 -5.972996185439744 0.7605222418992142 0.9408424635870498 1.5427859554839118 0.8441223015853725 0.08883772686912264 0.3200929402227568 0.36196610226836873 0.04823912553318759 0.12502748940817895 1.0641523650054987e-06 5.972996185439744 0.601943491896862 ASASGSGAQVGGPISSGS(ph)SASSVTVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASASGSGAQVGGPISSGSSASSVTVTR 27 0 P02545;P02545-3;P02545-5;P02545-4;A0A0C4DGC5 P02545 LMNA Prelamin-A/C;Lamin-A/C 1 ASASGSGAQVGGPIS(0.006)S(0.027)GS(0.531)S(0.354)AS(0.055)S(0.022)VT(0.004)VT(0.001)R 114.72 5.843400000000001e-06 0.0 9617.1 11499.0 13342.0 11172.0 11092.0 10210.0 8919.5 8023.5 12078.0 7780.2 True False 11245.085083616772 12640.544725756476 13660.123879816774 10546.0690601127 8918.602224588234 9674.56962632223 8074.580388412169 7812.891626600967 12254.617900668893 9190.688671970689 1.2235301928909288 1.3753642601676834 1.486300359784436 1.1474732130004126 0.9703954233362021 1.0526490420491839 0.8785609736773727 0.8500877252461332 1.3333731930276809 1.0 13.165957253511776 -5.969790595286521 4.5870618342075575 1.0049708696530402 1.3615674205327617 0.562448281109991 0.13676189157294363 0.13959752931592861 7.054773341161475 0.03953589410039361 0.058229810205023894 1.0720360866067728e-06 5.969790595286521 0.35659655087972153 ASASGSGAQVGGPISSGS(ph)SASSVTVTR ddPTM_PC-9_Lapatinib_30min_R1 1 ASASGSGAQVGGPISSGSSASSVTVTR 27 0 P02545;P02545-3;P02545-5;P02545-4;A0A0C4DGC5 P02545 LMNA Prelamin-A/C;Lamin-A/C 1 ASASGSGAQVGGPIS(0.001)S(0.02)GS(0.424)S(0.424)AS(0.092)S(0.034)VT(0.004)VT(0.002)R 152.03 2.5783e-10 4979400.0 12047.0 10455.0 13922.0 11054.0 12041.0 12363.0 9570.1 13114.0 16326.0 8420.0 True False 11875.207570850775 10430.792089853292 12777.386900474112 11866.948035063017 11332.772053516826 11834.263309560605 10065.592951141074 13723.32431501072 14487.193959598428 9875.385781055238 1.2025056877911502 1.0562414796861441 1.2938620509373944 1.2016693117780124 1.1475776546631131 1.1983595954563357 1.019260733130115 1.3896494394514993 1.467000305688351 1.0 13.269621392691752 -7.779733267346087 24.990878492974062 1.321243654153322 1.1636976464484488 0.1377611919388121 0.13523415294313978 375.51512801870575 512975.764213656 0.06986981729478613 0.0336631517874878 1.6606064966877717e-08 7.779733267346087 -0.15754600770487315 ASASPS(ph)TSSTSSRPK ddPTM_PC-9_AZD4547_30min_R2 1 ASASPSTSSTSSRPK 15 1 J3KP75;F6TH74;O75167-5;O75167-2;O75167;O75167-4;F5H858 J3KP75 PHACTR2 Phosphatase and actin regulator;Phosphatase and actin regulator 2 1 ASAS(0.115)PS(0.715)T(0.133)S(0.025)S(0.005)T(0.005)S(0.001)SRPK 131.56 4.4288999999999996e-05 1024600.0 3226.9 2663.8 3940.3 5376.4 4198.2 5617.1 2794.2 4214.8 1866.3 3606.6 True False 4252.987076310373 3524.8212565518543 3888.049047453717 4136.954044551967 3615.352396206909 5265.861849032109 3042.878386917349 3563.4995064687637 1964.948807873037 3480.3340317636025 1.2220054274949124 1.0127824583451572 1.1171482426597747 1.1886658024188652 1.0387946568378346 1.5130334620104609 0.8743064197706966 1.0238958312466975 0.5645862695763518 1.0 11.765010062817177 -7.460212597741176 24.99973911076891 0.8663627549241977 1.167584438079372 0.4437852286030789 0.17308379394842313 209.6748310732286 83646.6144596164 0.06971465131634026 0.04700154911086853 3.465671558456627e-08 7.460212597741176 0.3012216831551744 ASAVSELS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 ASAVSELSPR 10 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 ASAVSELS(1)PR;ASAVSELS(1)PR;ASAVSELS(1)PR;ASAVSELS(1)PR 122.18 0.0005605 3302430000.0 233606.0 211955.0 290553.0 430836.0 342849.0 305065.0 236313.0 320867.0 261670.0 298125.0 True False 307887.848693347 280465.3087440682 286700.0773760421 331513.4165498461 295250.3343545186 285989.2373244171 257344.39920105907 271284.3779401429 275501.34199010715 287687.7344921871 1.0702154168540283 0.9748949124964692 0.9965669126704746 1.1523376800718252 1.0262875296914575 0.9940960389890514 0.8945268370767052 0.9429820788814697 0.9576402083196532 1.0 18.134144187816723 -6.928285457637938 3.316076212158895 0.9438604290187186 1.0436041075061495 0.4367781236762982 0.050714858111798024 0.23679826622346264 5.255595870136265 0.02003792936637569 0.01709664471448575 1.1795450770204235e-07 6.928285457637938 0.09974367848743093 ASAVSELS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ASAVSELSPR 10 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 ASAVSELS(1)PR;ASAVS(0.001)ELS(0.999)PR;ASAVSELS(1)PR;ASAVSELS(1)PR;ASAVSELS(1)PR 144.7 0.00011211 2763656000.0 530936.0 542352.0 563390.0 648869.0 722637.0 563579.0 626851.0 566614.0 564255.0 432583.0 True False 620812.9783360007 596193.1222805016 576823.3542684724 612514.9735916809 581041.467343108 534023.9251158731 567471.1352717716 551740.982877157 572506.161909415 511006.87357485516 1.2148818547057383 1.1667027453265126 1.1287976426484918 1.198643316295737 1.137052156027396 1.0450425478232757 1.1104960903987628 1.0797134273700428 1.120349238953145 1.0 18.962983171481632 -6.564864425699079 5.300833722997965 1.0789842813937658 1.172673009526002 0.6313899551688442 0.03814245301827068 0.13340570509592334 8.968937873927981 0.012202015144960773 0.012367985933063985 2.7235513901385564e-07 6.564864425699079 0.09368872813223628 ASAVSELS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 6 ASAVSELSPR 10 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 ASAVSELS(1)PR;ASAVSELS(1)PR;ASAVSELS(1)PR;ASAVSELS(1)PR;AS(0.001)AVS(0.138)ELS(0.861)PR;ASAVSELS(1)PR 142.89 0.00011139 3470012000.0 813558.0 763552.0 822292.0 676227.0 774599.0 743456.0 663147.0 699662.0 879694.0 641398.0 True False 801956.5137317339 761784.0422564949 754686.3258989122 725958.9894071412 729038.6097402278 711660.119960582 697481.5068568088 732170.8507617067 780613.5981315062 752262.7896908866 1.0660589952365809 1.012656817133705 1.0032216616868972 0.9650337612810094 0.9691275704861038 0.9460259495927098 0.927177997390263 0.9732913295665788 1.0376873731216578 1.0 19.520877204365995 -4.805977099121884 1.121837353984256 0.9698375645716596 1.107249914243656 0.47857919431706697 0.028942998391573542 1.4039441569377817 1.5044977580641676 0.0095942155706116 0.22736579391735132 1.5632300714973426e-05 4.805977099121884 0.13741234967199645 ASAYVFAS(ph)PGCK ddPTM_PC-9_AZD4547_30min_R2 1 ASAYVFASPGCK 12 0 A6NF51;O95861-3;O95861-4;O95861;O95861-2 A6NF51 BPNT1 3(2),5-bisphosphate nucleotidase 1 1 ASAYVFAS(1)PGCK 105.19 0.0032044000000000005 0.0 18407.0 16140.0 18211.0 27997.0 24322.0 22754.0 18783.0 21715.0 19506.0 23212.0 True False 24260.043110615476 21356.939365097573 17969.51024114398 21542.724199338114 20945.31012827984 21331.188782979934 20454.650612507554 18359.445711058466 20537.04733771176 22399.354945182924 1.0830688280973333 0.9534622500229843 0.8022333806094001 0.9617564546862528 0.9350854156085516 0.9523126373586618 0.9131803421377728 0.8196417153971098 0.9168588733010965 1.0 14.45116956581512 -4.81885844843659 3.911268933611386 0.908523682294278 1.0929087875644181 0.4360190188533475 0.0577968074935549 0.19973450175831833 5.353752656629354 0.01443046171680093 0.0963204548151516 1.5175449071317619e-05 4.81885844843659 0.18438510527014007 ASDPAS(ph)PHIGR ddPTM_PC-9_AZD4547_30min_R2 2 ASDPASPHIGR 11 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 ASDPAS(1)PHIGR;ASDPAS(1)PHIGR 90.759 0.0048525 26610000.0 58751.0 68117.0 111213.0 147696.0 136030.0 115239.0 93426.0 143121.0 104250.0 113542.0 True False 77432.59590328507 90134.48814946417 109738.24295471661 113646.969080453 117144.58254871766 108033.08711267571 101740.7330098563 121004.93804339856 109760.44216940692 109566.92913949503 0.7067150326418461 0.8226431903983504 1.0015635540447014 1.0372378780075462 1.069160041891611 0.9860008668777556 0.9285715480838673 1.1043928947697461 1.0017661627594356 1.0 16.74145288618311 -5.096721279392898 2.2792359743672113 1.020687975947469 0.7028480716998674 0.8402265650515183 0.045249239717507446 0.13369113908368133 1.2084122507819863 0.012688247188215302 0.06459070434769733 8.003477357202379e-06 5.096721279392898 -0.31783990424760156 ASDPAS(ph)PHIGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASDPASPHIGR 11 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 AS(0.032)DPAS(0.968)PHIGR 67.252 0.04017 7600500.0 18319.0 17686.0 23340.0 25447.0 31876.0 21204.0 24295.0 21291.0 22998.0 17046.0 True False 21420.044883257506 19441.74919729795 23896.514117442915 24021.28709028712 25630.126623780627 20092.024912491335 21993.60171943199 20732.133809679202 23334.30224205856 20136.30486393824 1.0637525120916447 0.9655072928556939 1.1867377991599029 1.1929342177027935 1.2728316737834644 0.997800989220907 1.0922362304327222 1.029589785701349 1.158817489093918 1.0 14.297511343749495 ASDPAS(ph)PHIGR ddPTM_PC-9_Lapatinib_30min_R1 2 ASDPASPHIGR 11 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 AS(0.007)DPAS(0.993)PHIGR;AS(0.006)DPAS(0.994)PHIGR 79.283 0.010311 17392800.0 106842.0 95710.0 123209.0 92757.0 91339.0 95034.0 85786.0 85605.0 106372.0 76380.0 True False 105318.41348757698 95488.38937540505 113079.23162049375 99578.65920828127 85966.61959938315 90969.61735507408 90227.57932587822 89582.5208164171 94391.26521318157 89582.18123004718 1.1756625262017135 1.0659306132565662 1.262296028828614 1.1115900265094363 0.9596397232014338 1.015487858254578 1.0072045365157347 1.0000037907803234 1.0536834883578539 1.0 16.450924174247866 -6.078932539791812 5.305704761129744 1.0075151786654644 1.1622772773140553 0.692572101805691 0.049223380668814314 0.12271882409891088 6.010271343823305 0.014186678095695668 0.018710642538614212 8.338106927686684e-07 6.078932539791812 0.15476209864859092 ASDPQS(ph)PPQVSR ddPTM_PC-9_AZD4547_30min_R2 2 ASDPQSPPQVSR 12 0 Q7L7X3;Q7L7X3-3;Q7L7X3-2 Q7L7X3 TAOK1 Serine/threonine-protein kinase TAO1 1 ASDPQS(1)PPQVSR;ASDPQS(1)PPQVSR 156.96 8.6004e-05 58375000.0 89140.0 80106.0 108731.0 142231.0 129303.0 111183.0 100784.0 133830.0 128196.0 139220.0 True False 117484.66577281832 105998.69794179096 107289.15589642675 109441.84039704471 111351.51038224544 104230.70943386016 109753.58075552153 113149.64860745816 134972.17884267902 134345.95017526997 0.8744935416329697 0.7889980889152467 0.7986035735089559 0.8146270152115866 0.8288415857491379 0.7758381201508422 0.816947445102254 0.8422259730184739 1.0046613140670937 1.0 17.03559330676581 -8.2153610595699 3.599845777807586 1.0077521195870638 0.8125201606282874 0.8959155382870914 0.025306764865860133 0.06382398147397117 1.623237296165479 0.02075738411310619 0.00644511013718564 6.090303569067444e-09 8.2153610595699 -0.19523195895877643 ASDPQS(ph)PPQVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASDPQSPPQVSR 12 0 Q7L7X3;Q7L7X3-3;Q7L7X3-2 Q7L7X3 TAOK1 Serine/threonine-protein kinase TAO1 1 AS(0.062)DPQS(0.938)PPQVSR;ASDPQS(0.997)PPQVS(0.003)R 121.92 0.0004245 20254000.0 80247.0 64015.0 80007.0 82309.0 122185.0 111601.0 111094.0 94052.0 106331.0 83705.0 True False 93831.2321495041 70369.98613960344 81914.67030823724 77697.49357937842 98243.72636236138 105748.44709766784 100570.37206909133 91583.2346563314 107885.88971651116 98880.05389158468 0.9489399373950961 0.711670183925662 0.8284246122888561 0.7857751945055419 0.9935646522814299 1.0694618675432144 1.017094632445892 0.9262053473064067 1.0910783871012122 1.0 16.593391909089277 -6.306076105857161 5.696749563075911 1.016607256636375 0.8116313321124722 0.6661467147249576 0.06850278269743178 0.11630820860578003 9.670680306602398 0.020458258714760005 0.023599739044058415 4.942240714666432e-07 6.306076105857161 -0.2049759245239029 ASDPQS(ph)PPQVSR ddPTM_PC-9_Lapatinib_30min_R1 1 ASDPQSPPQVSR 12 0 Q7L7X3;Q7L7X3-3;Q7L7X3-2 Q7L7X3 TAOK1 Serine/threonine-protein kinase TAO1 1 ASDPQS(0.94)PPQVS(0.06)R 127.07 0.00024498 22706000.0 70966.0 79394.0 68428.0 55252.0 79527.0 59324.0 75414.0 79163.0 78636.0 68552.0 True False 69954.01182642936 79210.16807095284 62802.11397971859 59315.416395268825 74849.37821609773 56786.8508109984 79318.56791646394 82841.20197873966 69779.18560620988 80401.12186020166 0.8700626335545749 0.9851873486128764 0.7811099214376195 0.7377436411696364 0.930949425634171 0.7062942592982367 0.9865355865852218 1.0303488317337253 0.867888208420017 1.0 16.29492801143696 -7.3120590481831735 24.991289255462128 0.9737223218955957 0.8395013402244457 0.3639920812071187 0.08791564589824949 421.44101730128875 208066.7555492931 0.0369647724090552 0.024921675469046816 4.8746220854596775e-08 7.3120590481831735 -0.13422098167115004 ASDSGPSS(ph)SSSSSSSPPR ddPTM_PC-9_AZD4547_30min_R2 1 ASDSGPSSSSSSSSSPPR 18 0 Q16643-3 Q16643-3 DBN1 Drebrin 1 ASDS(0.01)GPS(0.036)S(0.179)S(0.179)S(0.028)S(0.028)S(0.135)S(0.135)S(0.135)S(0.135)PPR 62.693999999999996 0.020059999999999998 4663000.0 5008.7 4369.7 6070.0 7654.5 9378.5 9691.4 6625.6 9024.8 7280.4 7314.0 True False 6601.36241256803 5782.1200708591605 5989.507833932459 5889.873285846116 8076.4571596938 9085.395225954631 7215.265564512057 7630.224529272875 7665.22708076882 7057.939086208341 0.9353101991865457 0.8192363238381851 0.8486199385931703 0.8345032755178209 1.1443081416607446 1.2872589455621781 1.0222907106992665 1.081083930602747 1.0860432467810834 1.0 12.785031263603134 -6.260037250676652 24.984588628587364 1.1126794305032213 0.8557760954753261 0.6959642932920136 0.07887806981122714 70.61324330121646 1258258.929922079 0.024516917068816382 0.029963372090124746 5.494937401905869e-07 6.260037250676652 -0.2569033350278952 ASDSGPSSSSSSSS(ph)SPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASDSGPSSSSSSSSSPPR 18 0 Q16643-3 Q16643-3 DBN1 Drebrin 1 ASDSGPSSSSSSSS(0.748)S(0.251)PPR 246.38 1.7796e-53 4683900.0 5995.2 7923.2 8156.5 7158.5 8703.5 7366.1 5706.8 6284.4 5144.9 5429.7 True False 7010.0689494025555 8709.762933395401 8350.981893698501 6757.43245317013 6998.111653597518 6979.808748722061 5166.210590345936 6119.441158872202 5220.134429305467 6414.061628518451 1.092921982263799 1.3579169390374601 1.3019803016185627 1.0535340700695752 1.0910577507522288 1.0882041915045162 0.8054507252277916 0.9540664735218173 0.8138578535160158 1.0 12.647022500420256 -6.563145411316927 0.9621894559365042 0.8892109499033185 1.2521686059203185 0.6394959819400647 0.10228830765989054 0.32965895951346624 0.6625799409348194 0.05457290489017672 0.061639435956247234 2.7343530516532967e-07 6.563145411316927 0.36295765601700003 ASDSGPSSSSSSSSS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 3 ASDSGPSSSSSSSSSPPR 18 0 Q16643-3 Q16643-3 DBN1 Drebrin 1 ASDSGPSSSSS(0.001)S(0.015)S(0.162)S(0.162)S(0.66)PPR;ASDSGPSSSSSSSS(0.092)S(0.908)PPR;ASDSGPSSSSS(0.001)S(0.004)S(0.021)S(0.131)S(0.843)PPR 246.38 1.7509999999999997e-131 3954300.0 13627.3 11820.800000000001 18532.3 17685.3 20288.5 19088.800000000003 15369.55 21383.4 14384.3 15193.300000000001 True False 17960.497934551535 15641.642431657081 18286.5495932103 13608.227320161253 17471.791980001875 17895.174318385663 16737.410175236404 18079.086871648527 15144.624731869539 14661.387191480611 1.2250203681264185 1.0668596516396534 1.2472591682072338 0.928167788111392 1.191687508952381 1.2205648813902228 1.1415979918300037 1.2331088890520443 1.032959878494289 1.0 13.83973399049664 -8.42627791202327 6.099104674447974 1.0007713332985888 1.151685755147196 0.2725052296614112 0.09209121589687591 0.2832966990291286 13.597719033863365 0.08556557848988912 0.022180251617734136 3.747331277490109e-09 8.42627791202327 0.15091442184860715 ASDSGPSSSSSSSSS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASDSGPSSSSSSSSSPPR 18 0 Q16643-3 Q16643-3 DBN1 Drebrin 1 ASDSGPS(0.003)S(0.001)S(0.001)S(0.001)S(0.027)S(0.194)S(0.027)S(0.131)S(0.615)PPR;ASDSGPSSSS(0.001)S(0.004)S(0.007)S(0.022)S(0.205)S(0.761)PPR 181.86 3.8544e-33 0.0 7580.5 8863.599999999999 10390.599999999999 12279.7 10268.6 7143.9 9862.5 9027.8 6854.6 5272.7 True False 8863.728928300314 9743.519630508312 10638.351310569942 11591.70822032455 8256.541543761881 6769.261307882798 8928.252601683396 8790.829815744766 6954.835557370839 6228.598771329765 1.4230694982473506 1.5643196789874674 1.7079846850206926 1.8610459022792047 1.325585713076709 1.0868032371970566 1.4334287581309837 1.4113655636656108 1.1165971372861485 1.0 12.604691925756132 -6.427555114927011 6.582746064251722 1.2447519522299915 1.6369450048356884 0.6009082335814927 0.16469537538383489 0.18955422133754563 11.084681851875276 0.052936364992116756 0.05990093134901108 3.736327058386861e-07 6.427555114927011 0.3921930526056969 ASDSGPSSSSSSSSS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 3 ASDSGPSSSSSSSSSPPR 18 0 Q16643-3 Q16643-3 DBN1 Drebrin 1 ASDSGPSSSSSS(0.002)S(0.001)S(0.028)S(0.969)PPR;ASDSGPSSSSSSSS(0.025)S(0.975)PPR;ASDSGPSSSSS(0.001)S(0.003)S(0.021)S(0.106)S(0.87)PPR 226.06 6.249800000000001e-35 8280500.0 23207.92 25103.2 26062.3 20845.899999999998 28320.6 26907.399999999998 25061.3 25581.8 26713.8 24112.7 True False 22876.97080498871 25045.075082735995 23919.558297387328 22378.977025883843 26654.837988441872 25756.63322621297 26358.851488117314 26770.423818952342 23705.01053521501 28280.548066846844 0.8089295423453011 0.8855936958342127 0.8457954294537918 0.7913204854795093 0.9425149019544361 0.9107543872675986 0.9320488211831253 0.946602016187062 0.8382090219462289 1.0 14.787522458878525 -6.273314807084417 24.987496880772728 0.9249896363800189 0.8375933266486845 0.5265548453514921 0.04417944687687521 630.7649339009995 1327211.8269365884 0.013190104161796385 0.01506965519583524 5.32948437051734e-07 6.273314807084417 -0.08739630973133439 ASDSS(ph)SPSCSSGPR ddPTM_PC-9_AZD4547_30min_R2 1 ASDSSSPSCSSGPR 14 0 Q92610;H0YM74 Q92610 ZNF592 Zinc finger protein 592 1 AS(0.13)DS(0.016)S(0.762)S(0.088)PS(0.001)CS(0.002)S(0.001)GPR 145.49 0.00018581 21653000.0 18051.0 13938.0 19935.0 29721.0 21162.0 21853.0 16383.0 21166.0 17387.0 17941.0 True False 23790.84251587547 18443.185927554518 19670.6488747024 22869.282634872598 18224.02158270941 20486.528455412703 17841.0552619236 17895.2810462935 18306.041323735997 17312.891050815397 1.3741692503029397 1.0652863160417039 1.1361851014349196 1.3209395569895594 1.0526272896432916 1.1833106553539963 1.0305069909790328 1.0336390955022312 1.0573647850035899 1.0 14.079559037610947 -7.024132754457431 0.8199448833824345 1.0149553923832737 1.2082343116043943 0.4153343241962575 0.09373557553656474 0.6762636786153857 0.9420777985951818 0.06787479057046727 0.049789934899394546 9.459479612748115e-08 7.024132754457431 0.19327891922112062 ASDSS(ph)SPSCSSGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASDSSSPSCSSGPR 14 0 Q92610;H0YM74 Q92610 ZNF592 Zinc finger protein 592 1 AS(0.017)DS(0.005)S(0.915)S(0.057)PSCS(0.004)S(0.002)GPR 153.14 0.00025997 1606800.0 6803.8 6994.4 7027.9 7549.2 9529.2 9207.3 5831.0 7782.3 8435.5 6387.5 True False 7955.548958824577 7688.757807620761 7195.471789459173 7126.242798836623 7662.021665934564 8724.4529794747 5278.645467215806 7578.022871028435 8558.853229101876 7545.503186577824 1.0543430652810744 1.0189854297984744 0.953610595812709 0.9444357284896526 1.0154421085612961 1.1562453508725605 0.6995750100014039 1.004309809915455 1.1342985374821166 1.0 12.881401397551144 ASDSSS(ph)PSCSSGPR ddPTM_PC-9_AZD4547_30min_R2 2 ASDSSSPSCSSGPR 14 0 Q92610;H0YM74 Q92610 ZNF592 Zinc finger protein 592 1 ASDSS(0.048)S(0.885)PS(0.006)CS(0.06)SGPR;AS(0.071)DS(0.002)S(0.021)S(0.496)PS(0.013)CS(0.198)S(0.198)GPR 161.49 0.00051484 22961000.0 17406.7 15724.1 20746.9 31093.9 25168.4 21817.2 15030.6 21297.1 18404.8 19863.8 True False 22941.66851814799 20806.607823465358 20471.782550216354 23925.681750966167 21674.202098207326 20452.967035072063 16368.294281869552 18006.1225536718 19377.64015385611 19168.374408070176 1.196849979541781 1.085465432828016 1.06799784449105 1.2481852264369946 1.1307271882733132 1.067016252899414 0.8539218784759469 0.9393661752605871 1.0109172401024173 1.0 14.22644037264014 -7.023596589035212 4.227369584490069 0.945918545397022 1.1417076437506701 0.6815702912315244 0.06256699660369765 0.1272558716512686 5.274453033836504 0.024704141669954466 0.01992182289755033 9.47116518128816e-08 7.023596589035212 0.1957890983536481 ASDSSS(ph)PSCSSGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASDSSSPSCSSGPR 14 0 Q92610;H0YM74 Q92610 ZNF592 Zinc finger protein 592 1 AS(0.046)DS(0.003)S(0.047)S(0.842)PS(0.007)CS(0.045)S(0.01)GPR;ASDSS(0.127)S(0.868)PS(0.004)CS(0.001)SGPR 170.74 0.00014244 39756000.0 31983.0 29203.0 36182.0 35013.0 39435.0 33972.0 33068.0 31811.0 28396.0 26185.0 True False 37397.090206955865 32102.080844096567 37044.71610099915 33051.33512367756 31707.994836516133 32190.44851571194 29935.55964841231 30975.99495654056 28811.23778004586 30932.13321965404 1.2090045630346 1.0378230500992138 1.197612716780271 1.0685113402614275 1.0250827064319352 1.0406798744568442 0.967781932006923 1.0014179990941798 0.9314339096968398 1.0 14.91681871117551 -6.351343201782824 0.8639574624394093 0.9721492175766469 1.14856508085909 0.6551665995647458 0.05048290404369989 0.37884658792462816 0.6144719338966874 0.02560908175121154 0.03801182554206582 4.4530420708270987e-07 6.351343201782824 0.17641586328244308 ASDSSS(ph)PSCSSGPR ddPTM_PC-9_Lapatinib_30min_R1 3 ASDSSSPSCSSGPR 14 0 Q92610;H0YM74 Q92610 ZNF592 Zinc finger protein 592 1 ASDSS(0.023)S(0.973)PS(0.004)CSSGPR;AS(0.001)DSS(0.045)S(0.907)PS(0.006)CS(0.041)S(0.001)GPR;AS(0.061)DSS(0.006)S(0.904)PS(0.006)CS(0.018)S(0.005)GPR 205.26 9.857799999999998e-11 36158000.0 29650.5 32042.7 36565.5 30913.5 30647.1 30859.7 30047.0 27968.6 31865.0 22785.3 True False 29227.678432764253 31968.507096847618 33559.22573691181 33186.981914412914 28844.497832516852 29539.902568474266 31602.686638899886 29268.12326039415 28276.02814667426 26723.708745496184 1.0936984350156889 1.1962601224740317 1.25578474367139 1.241855396287613 1.0793598338919963 1.10538184837285 1.18257113710783 1.0952118786778344 1.0580877233755848 1.0 14.705832620049955 -8.096232486299462 0.5093368027361417 0.9960538523221759 1.1902280951294872 0.5038045970885444 0.05602205053605858 0.7719999417690925 0.49941193494101943 0.06453233552286068 0.0371890143242312 8.012490243443999e-09 8.096232486299462 0.19417424280731133 ASDVDTSS(ph)STLRKILMDPK ddPTM_PC-9_Lapatinib_30min_R1 1 ASDVDTSSSTLRKILMDPK 19 2 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 AS(0.002)DVDT(0.001)S(0.006)S(0.448)S(0.448)T(0.096)LRKILMDPK 50.077 0.019632 10197000.0 52213.0 15454.0 27558.0 26113.0 21664.0 18121.0 13151.0 11881.0 26681.0 18290.0 True False 51468.43304530848 15418.21721249093 25292.287616956295 28033.43713041437 20389.76611306275 17346.00707211417 13831.894431662799 12433.034633722913 23675.904816614344 21451.402130106922 2.399303911844197 0.7187510223796303 1.179050556395039 1.3068347215900447 0.9505097144417347 0.8086188010884915 0.6448014142744456 0.579590767928089 1.1036996403785346 1.0 14.388784329374072 -4.7567636579388255 24.999625964581828 0.9170304539307529 2.3993061458646774 0.7964231215933186 0.22416391145308207 67.94017349329721 363211.26387026004 0.06136362242736324 0.48297073876343927 1.750799210336605e-05 4.7567636579388255 1.4822756919339244 ASDVHEVR ddPTM_PC-9_AZD4547_30min_R2 2 ASDVHEVR 8 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ; 120.87 0.0028511 6763900.0 45633.0 31583.0 68177.0 86681.0 74482.0 80736.0 50901.0 67885.0 84694.0 96968.0 False True 60143.344774635465 41791.58711077304 67272.92843393954 66698.03465809999 64141.45995290434 75687.5651570128 55431.09039169708 57394.9330921116 89170.75193377209 93573.17983476204 0.6427412735234682 0.4466192896786398 0.7189338713585955 0.7127900833965456 0.6854684223211154 0.8088596036884406 0.5923822455278437 0.6133694846478822 0.9529520327430995 1.0 16.51380745995599 -14.52287873327556 0.08394216021617057 2.119385352485436 0.36798774447626864 0.5247656582492876 0.10902191450182983 198.02520963521562 1.1641833309798937 39.84346427833908 3.301645165603927 3.0000000829260683e-15 14.52287873327556 -1.751397608009167 ASDVHEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASDVHEVR 8 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ;; 118.33 0.0029439 12265100.0 34947.9 63740.0 79441.0 76961.0 119364.0 91184.0 57979.0 68158.0 91820.0 74698.0 False True 40863.88921751159 70067.68595701535 81335.17472167026 72649.1246809286 95975.48106164338 86402.15051974203 52486.8093883905 66368.92471937047 93162.69379362617 88240.1560909572 0.46309855997296107 0.7940566864454566 0.9217478563595316 0.8233113799803629 1.0876621859407487 0.9791704179521106 0.5948177305385492 0.7521397021437489 1.0557856867070232 1.0 16.42914772251241 -4.763987494451063 2.762970587797252 0.8883270214445845 0.3716600891524286 0.4645841901876131 0.14099898296116406 0.4644158895534338 4.639840746270697 0.03829150085601672 0.5661272687482849 1.7219181570614147e-05 4.763987494451063 -0.516666932292156 ASDVHEVR ddPTM_PC-9_Lapatinib_30min_R1 4 ASDVHEVR 8 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ;;; 119.21 0.0029118000000000004 84735400.0 394352.2 427160.1 652546.0 501979.0 743144.0 672249.0 637859.0 862806.0 960175.0 540725.0 False True 388728.66531266354 426171.03703308903 598896.1867804043 538896.2102128546 699433.7309973183 643498.4773589579 670884.2179519428 902895.1165881624 852029.9804090047 634188.5957792279 0.6129543607371754 0.671994166828958 0.9443502938499552 0.8497412501571594 1.1028797043219039 1.0146799889523257 1.0578623179554767 1.4237012816018468 1.3434962187582622 1.0 19.274552409020345 -5.699109612846258 0.5315341485639736 1.250050995289533 0.47966595728215145 0.7059511080440571 0.1322365323070667 0.9916590023230719 0.4173735392152683 0.09540873525674635 0.4280239309411121 1.9993571823767003e-06 5.699109612846258 -0.7703850380073815 ASDYSFMELLS(ph)QHDK ddPTM_PC-9_Lapatinib_30min_R1 1 ASDYSFMELLSQHDK 15 0 A0A1B0GVP4 A0A1B0GVP4 1 ASDYS(0.002)FMELLS(0.998)QHDK 61.423 0.041441000000000006 3600900.0 4411.0 11117.0 14630.0 16155.0 16095.0 16055.0 15119.0 12027.0 16118.0 14998.0 True False 4348.0983311216705 11091.25926952645 13427.177873433138 17343.09259150017 15148.323743987485 15368.365076032955 15901.78784216485 12585.818326722125 14302.621109935526 17590.38431642119 0.24718609058828697 0.6305296729175156 0.763324872947684 0.9859416530945169 0.8611707096044534 0.8736798923538067 0.9040045718228008 0.7154942211792871 0.8130931566164571 1.0 14.102499382844718 -4.764849987804484 1.5573377795264014 0.8658077426469162 5.401431436921201e-13 0.8499770624682157 0.08062720791527361 0.41729743707239264 0.9336229520115402 0.023433542212749882 0.5652271790920735 1.7185018824304832e-05 4.764849987804484 -0.865807742646376 down ASEAAS(ph)PLPDSPGDK ddPTM_PC-9_AZD4547_30min_R2 1 ASEAASPLPDSPGDK 15 0 Q68CZ2;Q68CZ2-2 Q68CZ2 TNS3 Tensin-3 1 AS(0.045)EAAS(0.955)PLPDSPGDK 184.01 5.078e-07 10939000.0 33408.0 37213.0 48347.0 48778.0 44899.0 61419.0 63883.0 83152.0 62821.0 55672.0 True False 44031.049070432 49241.37451012241 47705.88719063135 37532.98571258759 38665.54886315421 57578.460220701636 69568.46324223075 70302.76904287047 66141.58980838668 53722.940225238 0.8195949232456018 0.916580036455074 0.887998441459465 0.6986398278878139 0.7197213834731607 1.0717667346444375 1.2949489166184696 1.308617301065804 1.2311610185719997 1.0 15.713250644335112 -6.949317649253763 4.226904100212633 1.230365048234035 0.8143643828945853 0.7768570657414894 0.1015330242175208 0.09724040070638477 3.6766618234676205 0.03880174993725029 0.03328418802936495 1.1237827223935811e-07 6.949317649253763 -0.41600066533944957 ASEAAS(ph)PLPDSPGDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ASEAASPLPDSPGDK 15 0 Q68CZ2;Q68CZ2-2 Q68CZ2 TNS3 Tensin-3 1 ASEAAS(1)PLPDSPGDK;AS(0.001)EAAS(0.998)PLPDS(0.001)PGDK;ASEAAS(0.999)PLPDSPGDK;ASEAAS(1)PLPDSPGDK;AS(0.011)EAAS(0.989)PLPDS(0.001)PGDK 191.15 1.8903999999999998e-38 9568400.0 54894.7 70065.0 56449.4 75761.5 140069.0 122994.0 175777.0 135185.0 130207.0 129372.0 True False 64187.28849025356 77020.59015654655 57795.36778154164 71516.82877709695 112623.48494372985 116543.97812143757 159126.13004472505 131636.53699034717 132111.03104755693 152826.1194918118 0.4200020827833204 0.5039753048278713 0.3781772904640049 0.46796208013989854 0.736938720411363 0.7625920131256216 1.041223388867443 0.8613484228224486 0.8644532196908608 1.0 17.22153160970165 -6.517422031922693 1.5488738730852403 0.9242804268152538 0.43073677065760513 0.9050699864496131 0.07152435714103286 0.10908406208938258 0.5335956607010517 0.028490991275286284 0.03152810590036789 3.0379314371499244e-07 6.517422031922693 -0.49354365615764867 ASEAAS(ph)PLPDSPGDK ddPTM_PC-9_Lapatinib_30min_R1 3 ASEAASPLPDSPGDK 15 0 Q68CZ2;Q68CZ2-2 Q68CZ2 TNS3 Tensin-3 1 ASEAAS(1)PLPDSPGDK;ASEAAS(1)PLPDSPGDK;ASEAAS(1)PLPDSPGDK 183.76 5.2164e-07 25085000.0 52243.5 78858.0 70569.0 65209.4 177775.0 207333.0 216524.0 192984.0 207780.0 187564.0 True False 51498.49810971545 78675.409146021 64767.0892242176 70005.11680818142 167318.62401909783 198465.85090682926 227734.55325993127 201950.74116272913 184377.6283796006 219984.18748667964 0.23410090833384903 0.35764120160129653 0.2944170213513157 0.3182279490539307 0.7605938678171094 0.9021823485328765 1.0352314675968286 0.9180238973992507 0.8381403703880531 1.0 17.747040300666654 -6.37451514176837 2.4783364926606284 0.939270381599429 0.29417300919364364 0.9641629345768794 0.0582378433906829 0.051645353318542794 0.6200382153412484 0.020506632047879312 0.024117364708249826 4.2216755983385657e-07 6.37451514176837 -0.6450973724057854 down ASEAAS(ph)PLPDSPGDKLVIVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASEAASPLPDSPGDKLVIVK 20 1 Q68CZ2;Q68CZ2-2 Q68CZ2 TNS3 Tensin-3 1 AS(0.185)EAAS(0.815)PLPDSPGDKLVIVK 59.356 0.007335899999999999 3824400.0 9049.8 3495.1 10351.0 13113.0 27113.0 31325.0 31323.0 37571.0 39285.0 30542.0 True False 10581.752398302518 3842.070429688798 10597.807096386106 12378.321122919599 21800.402282299015 29682.261855489127 28355.858681118287 36584.801059765035 39859.46880508178 36079.022829661015 0.29329376375468597 0.10649042375200317 0.2937387508087807 0.3430891457720752 0.6042403749465364 0.8227013795697086 0.78593754645169 1.0140186233006347 1.1047823826401644 1.0 15.138872644476084 -6.600761993744507 0.8023074622393068 1.0453568840529348 0.16572367050412964 0.9525886339014756 0.07397634350847564 0.1223068835805677 0.1745445390594443 0.04654802114126968 0.05317267367671472 2.5074830516306e-07 6.600761993744507 -0.8796332135488052 down ASEDS(ph)EEEPSGK ddPTM_PC-9_Lapatinib_30min_R1 1 ASEDSEEEPSGK 12 0 Q8IY33-4;Q8IY33-2;Q8IY33 Q8IY33-4 MICALL2 MICAL-like protein 2 1 AS(0.011)EDS(0.989)EEEPSGK 119.21 0.0016894000000000002 0.0 8732.3 9740.0 12347.0 9799.6 12182.0 9144.1 7783.2 8891.5 9324.4 8633.1 True False 8607.775800692301 9717.44762842382 11331.877320798296 10520.295274507282 11465.4787107335 8753.028158938208 8186.176012509917 9304.63155001661 8274.187881715026 10125.31983211734 0.8501238423490174 0.9597175980160394 1.1191624075768725 1.03900868801567 1.132357189781324 0.8644693011250622 0.8084856723778253 0.9189469275333385 0.8171779280956089 1.0 13.30567985919333 -6.789703969069745 24.965398724568324 0.8721669107437809 1.0232776689470902 0.3684402427022544 0.09001658218622657 223.07510625695457 197035.03087901117 0.03252165417700707 0.028686914097771292 1.6229159590216126e-07 6.789703969069745 0.15111075820330921 ASEDT(ph)TSGSPPKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASEDTTSGSPPKK 13 1 H0YER7;G3V1C3;Q9BZZ5-1;Q9BZZ5-5;Q9BZZ5-2;Q9BZZ5-6;Q9BZZ5 H0YER7 API5 Apoptosis inhibitor 5 1 ASEDT(0.588)T(0.261)S(0.075)GS(0.075)PPKK 101.39 0.0068682000000000005 117200000.0 32676.0 35843.0 27969.0 38867.0 37764.0 33403.0 38165.0 36320.0 35490.0 32154.0 True False 38207.401419581984 39401.25616186533 28635.887033023188 36689.40799851417 30364.415291142283 31651.28787737919 34549.73490932794 35366.63848422098 36008.974109516406 37983.26566907606 1.0059009078487002 1.0373319794338725 0.7539079783847282 0.9659361129757918 0.7994156046425297 0.8332955926732748 0.9096041190964915 0.9311110527553875 0.9480220690669308 1.0 15.213076328271248 -10.375428283830503 13.338668558058467 0.9999999991698272 0.9054170203116676 0.09025251624534936 0.08546743484194923 0.0 0.0 0.08439159658588906 0.02046796862577267 4.2128084820502984e-11 10.375428283830503 -0.09458297885815958 ASEDT(ph)TSGSPPKK ddPTM_PC-9_Lapatinib_30min_R1 1 ASEDTTSGSPPKK 13 1 H0YER7;G3V1C3;Q9BZZ5-1;Q9BZZ5-5;Q9BZZ5-2;Q9BZZ5-6;Q9BZZ5 H0YER7 API5 Apoptosis inhibitor 5 1 ASEDT(0.594)T(0.283)S(0.019)GS(0.104)PPKK 111.39 0.0019480999999999997 100480000.0 22792.0 20166.0 17034.0 18818.0 20377.0 15654.0 17578.0 16660.0 16377.0 12338.0 True False 22466.9819004591 20119.30686599535 15633.530273141492 20201.93849500777 19178.464922723408 14984.514911256292 18488.102830185453 17434.084420320163 14532.449802544616 14470.6068606484 1.5525943118222754 1.3903568150074006 1.0803645226279739 1.3960671234836213 1.325339366027394 1.0355139252663563 1.277631477948744 1.204792901100139 1.0042736937359822 1.0 13.820837805668518 -1.5228787452803376 0.17547544893863662 0.9945801942713071 2.9922310830844565 0.5511589529468657 0.12231277193382581 49.677810360876165 0.5499279826871293 0.3042869289058693 26.270336624809435 0.029999999999999995 1.5228787452803376 1.9976508888131495 ASEDTTS(ph)GSPPK ddPTM_PC-9_AZD4547_30min_R2 1 ASEDTTSGSPPK 12 0 H0YER7;G3V1C3;Q9BZZ5-1;Q9BZZ5-5;Q9BZZ5-2;Q9BZZ5-6;Q9BZZ5 H0YER7 API5 Apoptosis inhibitor 5 1 ASEDT(0.002)T(0.04)S(0.882)GS(0.076)PPK 193.0 2.2655999999999998e-05 17571000.0 104120.0 101090.0 95556.0 107710.0 105910.0 103090.0 112110.0 97177.0 103570.0 102040.0 True False 137227.99416946172 133765.36557730575 94288.86500481867 82879.12360291136 91206.22463967276 96643.7660032259 122087.57281415246 82160.52755530874 109044.49875765445 98467.61065855889 1.3936358692129365 1.3584707162352452 0.9575622316232469 0.8416891914875304 0.9262560960876228 0.9814777200021919 1.2398754473437659 0.8343914004393208 1.1074148953991727 1.0 16.5873616307516 -5.251571035830953 9.686302604776307 0.981727403159429 1.3766083137068388 0.6545036383595704 0.11329863974958881 0.14095646206284004 122.79053702204135 0.029466393453101505 0.07230135591193142 5.603107620529853e-06 5.251571035830953 0.3948809105474098 ASEDTTS(ph)GSPPKK ddPTM_PC-9_AZD4547_30min_R2 1 ASEDTTSGSPPKK 13 1 H0YER7;G3V1C3;Q9BZZ5-1;Q9BZZ5-5;Q9BZZ5-2;Q9BZZ5-6;Q9BZZ5 H0YER7 API5 Apoptosis inhibitor 5 1 ASEDT(0.058)T(0.009)S(0.68)GS(0.253)PPKK 147.68 0.00016338 104210000.0 22474.0 19557.0 18778.0 28310.0 20993.0 20613.0 23432.0 21411.0 22198.0 20778.0 True False 29620.264511760317 25878.417792020635 18528.99145067276 21783.566885139906 18078.484315557056 19324.065851435575 25517.402606201176 18102.42192583343 23371.34096188482 20050.56854433098 1.4772780355964037 1.2906575559094255 0.9241130200226453 1.086431381582888 0.9016444733517791 0.9637664791754339 1.272652321543065 0.9028383352726244 1.165619863108208 1.0 14.29135552518015 -5.043901949194701 3.604863060890077 1.0285166720834882 1.4565727038694196 0.6235157449879098 0.11490216259455995 0.1376220413431192 3.5826684327665435 0.028790653830294947 0.10945633887486393 9.038535139877875e-06 5.043901949194701 0.42805603178593143 ASEDTTS(ph)GSPPKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASEDTTSGSPPKK 13 1 H0YER7;G3V1C3;Q9BZZ5-1;Q9BZZ5-5;Q9BZZ5-2;Q9BZZ5-6;Q9BZZ5 H0YER7 API5 Apoptosis inhibitor 5 1 AS(0.007)EDT(0.396)T(0.059)S(0.43)GS(0.108)PPKK 123.38 0.0002458 123570000.0 16013.0 15022.0 11335.0 19576.0 17080.0 15580.0 16839.0 18032.0 13249.0 14905.0 True False 18723.68462883359 16513.284883060594 11605.269388226881 18479.220186248298 13733.296609805897 14762.957372977504 15243.888016197381 17558.67910648328 13442.741560354556 17607.158512084916 1.0634131916278446 0.9378733582551934 0.6591222189691451 1.049528813724533 0.7799836981293636 0.8384633649344807 0.8657778599388725 0.9972466082151551 0.763481600459719 1.0 14.103874481717328 -10.812172725803666 17.83066649944153 0.9999999238950752 0.8821372956376053 0.07304572624558991 0.12396081339504379 0.0 0.0 0.11501490757389694 0.02789521249693117 1.541087416142288e-11 10.812172725803666 -0.11786262825746985 ASEDTTS(ph)GSPPKK ddPTM_PC-9_Lapatinib_30min_R1 1 ASEDTTSGSPPKK 13 1 H0YER7;G3V1C3;Q9BZZ5-1;Q9BZZ5-5;Q9BZZ5-2;Q9BZZ5-6;Q9BZZ5 H0YER7 API5 Apoptosis inhibitor 5 1 ASEDT(0.175)T(0.091)S(0.445)GS(0.29)PPKK 77.527 0.023532 107270000.0 29652.0 23902.0 27520.0 23448.0 26959.0 25717.0 24340.0 25190.0 26842.0 19907.0 True False 29229.15704248917 23846.656387534513 25257.411830272038 25172.444140234977 25373.324623433276 24617.143859255033 25600.206103465338 26360.41936061614 23818.771301209174 23347.898425589858 1.2518967022082514 1.021362006672001 1.0817852369354712 1.0781460361608124 1.086749829081983 1.054362298932826 1.0964672552886772 1.1290274987544269 1.0201676770660963 1.0 14.511005076489548 -1.523050586941124 0.011512657762924374 1.7719135959089836e-08 2.3293803275800165 0.2774048377490842 0.057848342968232 15036.821181355948 13.427056290035637 1144.6798945987716 1608.4824030418322 0.029988131946736312 1.523050586941124 2.3293803098608805 ASEDTTSGS(ph)PPK ddPTM_PC-9_AZD4547_30min_R2 3 ASEDTTSGSPPK 12 0 H0YER7;G3V1C3;Q9BZZ5-1;Q9BZZ5-5;Q9BZZ5-2;Q9BZZ5-6;Q9BZZ5 H0YER7 API5 Apoptosis inhibitor 5 1 ASEDT(0.005)T(0.01)S(0.047)GS(0.938)PPK;ASEDTTSGS(0.999)PPK;ASEDT(0.005)T(0.005)S(0.027)GS(0.963)PPK 136.24 6.2816e-05 136139000.0 76882.0 73478.0 68605.0 81470.0 79847.0 79697.0 82265.0 68876.0 68847.0 66892.0 True False 101328.87675505716 97228.32655939527 67695.25287428926 62688.3501989527 68761.6223095454 74713.53399126099 89586.42563157824 58232.7968130261 72486.11186606386 64550.131440340214 1.5697702621831116 1.5062452142217175 1.0487237030160952 0.971157591784174 1.0652437225956328 1.1574497576401406 1.3878581442452609 0.9021328928949921 1.1229429011009588 1.0 15.978132412775702 -5.235267214482423 6.409000160417201 1.0872736216674612 1.5435027201195737 0.6812998335238531 0.12477185226488678 0.10733858755992606 16.40521537833046 0.03323384398550542 0.08583612337855745 5.81745169087937e-06 5.235267214482423 0.45622909845211246 ASEDTTSGS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 ASEDTTSGSPPK 12 0 H0YER7;G3V1C3;Q9BZZ5-1;Q9BZZ5-5;Q9BZZ5-2;Q9BZZ5-6;Q9BZZ5 H0YER7 API5 Apoptosis inhibitor 5 1 ASEDT(0.001)T(0.002)S(0.002)GS(0.996)PPK;ASEDT(0.007)T(0.282)S(0.114)GS(0.597)PPK;ASEDTT(0.001)S(0.001)GS(0.997)PPK;ASEDT(0.003)T(0.006)S(0.004)GS(0.987)PPK;ASEDT(0.001)T(0.005)S(0.027)GS(0.967)PPK;ASEDT(0.003)T(0.013)S(0.013)GS(0.97)PPK 169.09 0.00016677 158010600.0 299179.0 307641.0 233519.0 321481.0 314461.0 270226.0 342367.0 290117.0 258687.0 238974.0 True False 349824.09564540046 338181.5653514609 239086.97858573886 303469.46182546456 252844.62442717588 256054.87285431445 309935.51923757093 282501.73615437077 262469.80798727775 282298.0944828569 1.2392010519456205 1.1979590792880737 0.846930897722577 1.0749964939770194 0.8956653600172648 0.9070371988283608 1.0979015632583107 1.0007213710453373 0.9297611748605576 1.0 18.106859865040178 -5.1531200010309455 6.474769307043243 0.9730465001678679 1.2270808764724743 0.6405395653888923 0.07485726206522682 0.141546413340488 7.271152367529122 0.01874131949077136 0.05099791987166866 7.028780789905227e-06 5.1531200010309455 0.25403437630460646 ASEDTTSGS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 4 ASEDTTSGSPPK 12 0 H0YER7;G3V1C3;Q9BZZ5-1;Q9BZZ5-5;Q9BZZ5-2;Q9BZZ5-6;Q9BZZ5 H0YER7 API5 Apoptosis inhibitor 5 1 ASEDT(0.001)T(0.002)S(0.008)GS(0.989)PPK;ASEDT(0.011)T(0.011)S(0.224)GS(0.754)PPK;ASEDT(0.003)T(0.008)S(0.008)GS(0.982)PPK;ASEDT(0.001)T(0.001)S(0.003)GS(0.995)PPK 164.13 0.0003741 148774000.0 185140.0 160719.0 122711.0 148879.0 142066.0 136474.0 137031.0 132658.0 135132.0 117657.0 True False 182499.86964948243 160346.86503004606 112622.17525815834 159828.0583057852 133709.95719250245 130637.32515643247 144125.79468216765 138821.77497183875 119912.01115695546 137993.8556819021 1.322521707561921 1.161985540861118 0.8161390570734575 1.1582259044505174 0.9689558751132028 0.946689434184464 1.0444363190662682 1.0059996822745874 0.8689663069736367 1.0 17.07424450539247 -5.014772546483036 5.116513347637163 0.9834903538013074 1.2934011057505386 0.6117956812848779 0.08887016046706542 0.09975376941247813 8.02104308508465 0.021607684234551526 0.07340783002945209 9.665569623718252e-06 5.014772546483036 0.3099107519492311 ASEDTTSGS(ph)PPKK ddPTM_PC-9_AZD4547_30min_R2 2 ASEDTTSGSPPKK 13 1 H0YER7;G3V1C3;Q9BZZ5-1;Q9BZZ5-5;Q9BZZ5-2;Q9BZZ5-6;Q9BZZ5 H0YER7 API5 Apoptosis inhibitor 5 1 ASEDT(0.116)T(0.028)S(0.018)GS(0.837)PPKK;ASEDT(0.004)T(0.011)S(0.101)GS(0.884)PPKK 138.81 2.442e-05 932860000.0 152014.0 144638.0 135187.0 170538.0 164985.0 162550.0 158538.0 152287.0 165140.0 158468.0 True False 200351.28991237583 191389.40494975107 133394.33205038344 131223.09888583512 142079.6805983987 152385.72280361236 172647.57487119807 128754.54335712432 173868.96326000793 152920.08355390493 1.3101698956484757 1.2515648729833813 0.8723140149433767 0.8581155322190134 0.9291106654955171 0.9965056208584648 1.1290052350143998 0.8419727505036174 1.136992337561197 1.0 17.22241836799543 -5.185878073490967 5.918027358235573 0.9662584779464223 1.290101801539725 0.6160072534283043 0.09812222859952315 0.1437451744634256 8.707000966507982 0.02514293152056618 0.06872231721009257 6.518113619141766e-06 5.185878073490967 0.3238433235933027 ASEDTTSGS(ph)PPKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASEDTTSGSPPKK 13 1 H0YER7;G3V1C3;Q9BZZ5-1;Q9BZZ5-5;Q9BZZ5-2;Q9BZZ5-6;Q9BZZ5 H0YER7 API5 Apoptosis inhibitor 5 1 ASEDT(0.022)T(0.005)S(0.026)GS(0.948)PPKK;AS(0.004)EDT(0.041)T(0.12)S(0.358)GS(0.478)PPKK;ASEDT(0.002)T(0.002)S(0.05)GS(0.945)PPKK 150.59 0.00018887 829520000.0 102233.6 98998.8 79586.5 134943.4 116517.6 90704.2 119847.4 115832.0 93297.5 85554.8 True False 119539.7292743599 108826.74660372373 81484.14399348192 127382.95879040539 93686.81270859 85947.51207638175 108494.58665196369 112791.53273414884 94661.79943597071 101065.20798857596 1.1827980336009623 1.0767973348061095 0.8062531667939831 1.2604036673511254 0.9269937159697926 0.8504164171521513 1.0735107443129936 1.1160273152250217 0.9366408215047747 1.0 16.624926904901102 -4.998722740550468 15.378975599184109 1.0007051042520374 1.15632569377307 0.1752097786070217 0.1251720209781467 0.6466905864732926 7423.814309254706 0.03069851249637556 0.10956167939744253 1.002945327547468e-05 4.998722740550468 0.15562058952103253 ASEDTTSGS(ph)PPKK ddPTM_PC-9_Lapatinib_30min_R1 1 ASEDTTSGSPPKK 13 1 H0YER7;G3V1C3;Q9BZZ5-1;Q9BZZ5-5;Q9BZZ5-2;Q9BZZ5-6;Q9BZZ5 H0YER7 API5 Apoptosis inhibitor 5 1 ASEDT(0.002)TS(0.053)GS(0.945)PPKK 140.31 0.00010611 159720000.0 26441.0 21744.0 19265.0 22729.0 20450.0 21342.0 22610.0 20620.0 19597.0 15172.0 True False 26063.94649131445 21693.65310394737 17681.106065050546 24400.566481721307 19247.17120624691 20429.2524106319 23780.635168420347 21578.080477010913 17389.779494441416 17794.45998458077 1.4647225324004967 1.2191239926777953 0.9936298196388961 1.371245123643249 1.0816383988570004 1.1480681306616904 1.3364066787655657 1.212629127026542 0.977258062875186 1.0 14.119140531032231 -1.5228787461089348 0.02487381812095488 6.8687072118967e-05 2.793666405941514 0.2746927879506671 0.13827984444584668 3180.3849710509344 6.105837481011883 236.42006469228986 492.3551434208509 0.02999999994276253 1.5228787461089348 2.7935977188693952 ASEENLLSSSSVPSADRDS(ph)SPTTNSK ddPTM_PC-9_AZD4547_30min_R2 2 ASEENLLSSSSVPSADRDSSPTTNSK 26 1 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 ASEENLLSSSSVPS(0.008)ADRDS(0.402)S(0.402)PT(0.136)T(0.047)NS(0.006)K;ASEENLLSSSSVPS(0.071)ADRDS(0.413)S(0.413)PT(0.098)T(0.004)NSK 101.41 9.876e-10 81350000.0 63396.0 60740.0 83730.0 99117.0 111412.0 91755.0 77132.0 83247.0 67028.0 81012.0 True False 83554.60928128297 80373.01716456188 82619.68549178982 76267.10699238474 95944.36691110599 86017.54534509654 83996.59857551678 70383.08897575326 70570.96323962597 78175.79453813365 1.0688040943482267 1.0281061758234697 1.056844845388664 0.9755846735293766 1.227289949247717 1.1003091922927337 1.0744578813911994 0.9003181789399127 0.902721407010477 1.0 16.254434356576645 -7.754945280694171 24.88272841808304 0.9261398341235966 1.076243300869344 0.4937228233460276 0.06553543985651597 115.59087035126846 442902.06963447074 0.032854822728601726 0.018389718890978454 1.7581451190066228e-08 7.754945280694171 0.15010346674574737 ASEENLLSSSSVPSADRDS(ph)SPTTNSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASEENLLSSSSVPSADRDSSPTTNSK 26 1 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 ASEENLLS(0.001)S(0.001)S(0.001)S(0.001)VPS(0.036)ADRDS(0.368)S(0.368)PT(0.113)T(0.1)NS(0.013)K;ASEENLLSSS(0.003)S(0.003)VPS(0.022)ADRDS(0.369)S(0.369)PT(0.155)T(0.066)NS(0.013)K;ASEENLLSSSSVPS(0.001)ADRDS(0.467)S(0.467)PT(0.047)T(0.017)NS(0.002)K 90.37799999999999 2.5189e-07 34810600.0 82752.0 65464.0 74786.0 82401.0 102791.0 81110.0 87213.0 80357.0 81322.0 64475.0 True False 96760.27917349887 71962.83328349609 76569.18186748432 77784.33911764651 82649.84144136764 76856.44881400545 78951.55327255905 78247.71389527922 82511.18040389096 76163.80711618085 1.270423352471076 0.9448429117221443 1.0053224066213644 1.0212769301171314 1.0851590088622138 1.0090941055082505 1.0366019801521442 1.0273608536390462 1.0833384454906223 1.0 16.216817974402737 -4.749503174432637 24.999974318145615 1.0257439155438348 1.2704239037271623 0.7862235588472772 0.038587234484750786 250.91694552042088 525504.5676064785 0.009697079047153154 0.15720874216503528 1.7803148957702122e-05 4.749503174432637 0.24467998818332748 ASEENLLSSSSVPSADRDS(ph)SPTTNSK ddPTM_PC-9_Lapatinib_30min_R1 2 ASEENLLSSSSVPSADRDSSPTTNSK 26 1 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 ASEENLLSSSSVPS(0.003)ADRDS(0.489)S(0.489)PT(0.015)T(0.003)NSK;ASEENLLSSSSVPS(0.02)ADRDS(0.474)S(0.474)PT(0.031)T(0.001)NSK 135.62 3.918600000000001e-11 83144000.0 72142.0 73476.0 82387.0 74999.0 74968.0 87489.0 77070.0 64037.0 90420.0 61416.0 True False 71113.24185077733 73305.87083635187 75613.45888301678 80514.67664932978 70558.52963275889 83747.29941682017 81060.30749359378 67012.39279856185 80235.94743518859 72031.67376832414 0.9872496102131297 1.0176893996955554 1.0497251407236872 1.1177676768735039 0.9795486616026259 1.1626454729648108 1.1253425507549426 0.9303184181738463 1.1138981400494996 1.0 16.136343807498598 -5.123763973861793 2.510254398472487 1.0630330770733951 0.9899350311934891 0.10617916657472992 0.06933530537509489 0.7212736844622243 8.224509185808786 0.018404193037908682 0.08014911799818378 7.5203148973314965e-06 5.123763973861793 -0.07309804587990598 ASEENLLSSSSVPSADRDSSPT(ph)TNSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASEENLLSSSSVPSADRDSSPTTNSK 26 1 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 ASEENLLSSSSVPS(0.002)ADRDS(0.31)S(0.31)PT(0.343)T(0.03)NS(0.004)K 94.72 3.4771999999999995e-09 24467000.0 37315.0 38232.0 41300.0 49729.0 65802.0 51921.0 56175.0 45453.0 46879.0 35999.0 True False 43631.69249515553 42027.42029351439 42284.7486311222 46942.84535359329 52908.57046360933 49198.1713583033 50853.69732821948 44259.90691143435 47564.51668864523 42525.33373207281 1.0260164627996393 0.9882913690531983 0.9943425464344056 1.1038795285970624 1.244165908184406 1.1569144093794095 1.1958447557077108 1.0407891726444776 1.1184983753054438 1.0 15.376034937524345 -5.838346170736566 4.645821382859391 1.1361517347235508 1.0012224709830975 0.40002614026688676 0.06684110491700108 0.19152424850647704 7.6066316096845945 0.01927083148729609 0.02978931791148488 1.4509546186320116e-06 5.838346170736566 -0.13492926374045333 ASEGLDACAS(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 1 ASEGLDACASPTK 13 0 Q92618 Q92618 ZNF516 Zinc finger protein 516 1 ASEGLDACAS(0.737)PT(0.263)K 152.88 0.00014223 7703100.0 24900.0 22884.0 31803.0 36918.0 34629.0 29263.0 25816.0 25181.0 27430.0 28030.0 True False 32817.68204782555 30280.80547898966 31381.27144028894 28407.125477414174 29821.361090050283 27433.179984017843 28113.57398778123 21289.85505181502 28879.893800545135 27048.678231667996 1.2132822819195404 1.1194929829708855 1.1601776312880396 1.050222315268468 1.1025071478404476 1.0142151771357049 1.0393696041999745 0.7870941001061311 1.0677007413520558 1.0 14.723270476181622 -6.451823161469717 0.7330207684656003 0.9499860886896055 1.1757359009839066 0.5050656675163505 0.07688002518266694 0.559151398511412 0.6663985901210534 0.04748865423671346 0.06697726869193174 3.533270102335763e-07 6.451823161469717 0.22574981229430102 ASEGLDACAS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASEGLDACASPTK 13 0 Q92618 Q92618 ZNF516 Zinc finger protein 516 1 ASEGLDACAS(0.583)PT(0.417)K 144.4 9.163799999999999e-05 5617100.0 40204.0 38811.0 42339.0 54442.0 54698.0 47634.0 60298.0 53331.0 44745.0 36499.0 True False 47009.74313480456 42663.89958703666 43348.522331551656 51391.791243345426 43980.3195528784 45135.989185135506 54586.13692028443 51931.117758865345 45399.31097577661 43115.979774074964 1.0903090543490528 0.9895147880343397 1.005393419300575 1.1919430223465917 1.0200468546309864 1.0468505974268767 1.2660303026003903 1.2044517608316256 1.052957887392706 1.0 15.39593504394791 ASEGLDACAS(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 2 ASEGLDACASPTK 13 0 Q92618 Q92618 ZNF516 Zinc finger protein 516 1 ASEGLDACAS(0.831)PT(0.169)K;ASEGLDACAS(0.5)PT(0.5)K 162.94 0.00033793 32290000.0 88621.0 108974.0 107767.0 111883.0 122273.0 99917.0 109284.0 97820.0 114294.0 106600.0 True False 87357.24828889886 108721.67739834251 98906.81325264982 120111.24905074696 115081.14253796726 95643.78282790318 114942.19078928126 102365.07430946671 101421.00615082336 125025.6679644283 0.6987145096777513 0.8695948533486377 0.7910920602383049 0.9606927201934281 0.920460129600824 0.7649931760821729 0.9193487438274199 0.8187524688017754 0.8112014740819395 1.0 16.93186478727189 ASEGLDACASPT(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 ASEGLDACASPTK 13 0 Q92618 Q92618 ZNF516 Zinc finger protein 516 1 ASEGLDACAS(0.306)PT(0.694)K 142.1 0.00019581 6036100.0 27418.0 24859.0 30819.0 41744.0 39283.0 32214.0 28918.0 31174.0 35720.0 28976.0 True False 36136.35367017194 32894.185605759645 30410.319923223145 32120.565738370904 33829.23352393791 30199.653487514952 31491.645978410965 26356.77460725474 37608.08627617468 27961.55905960799 1.2923583264129537 1.1764074219050649 1.0875759773764735 1.1487401567951492 1.2098479005344913 1.0800418325435943 1.1262478573271824 0.9426074758945954 1.3449924661211625 1.0 14.771157183211933 ASEGLDACASPT(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASEGLDACASPTK 13 0 Q92618 Q92618 ZNF516 Zinc finger protein 516 1 ASEGLDACAS(0.322)PT(0.677)K 128.95 0.00024124 5387000.0 23957.0 26492.0 30304.0 32204.0 30789.0 25893.0 32376.0 33912.0 29108.0 24169.0 True False 28012.446927681645 29121.95068047139 31026.562288559984 30399.714286776692 24756.11647068582 24535.125497978606 29309.11089805848 33021.84593273409 29533.649433074203 28550.648378301266 0.9811492389423752 1.0200101340817296 1.0867200589441055 1.0647644103900888 0.8670947203251846 0.8593544066980107 1.0265655094661055 1.156605814872876 1.0344300781456166 1.0 14.801235888764127 -10.721961670129696 5.69010348214983 0.9999996974309536 1.0109175932464498 0.0013742557147001788 0.08677182329536702 3.723331591454398e-07 5.2398141321918504e-08 0.0939343192533606 0.022781787391165254 1.896873327667551e-11 10.721961670129696 0.010917895815496181 ASEGLDACASPT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 2 ASEGLDACASPTK 13 0 Q92618 Q92618 ZNF516 Zinc finger protein 516 1 ASEGLDACAS(0.038)PT(0.962)K;ASEGLDACAS(0.411)PT(0.589)K 106.76 0.0026484 25593600.0 68714.0 87266.0 91241.0 89074.0 106129.0 95161.0 77261.0 88521.0 85582.0 82496.0 True False 67734.1257593956 87063.94093860702 83739.51718044518 95624.79910215313 99886.70087764204 91091.18586112572 81261.19653902369 92634.0088217986 75942.85394158718 96755.32368098944 0.700055802435438 0.8998361808562003 0.8654771023922313 0.9883156343669135 1.0323638749530415 0.941459161063438 0.8398627945987632 0.9574047742036483 0.7848958698332429 1.0 16.56205342309964 -4.254976156560504 1.485856783378427 0.9294491705784871 0.123493853384746 0.4621839839429971 0.07273196931335177 4.4598143052551915 3.086469147696056 0.0208088968586814 7.812105494927803 5.559347781126745e-05 4.254976156560504 -0.805955317193741 ASEIDQVVPAAQS(ph)SPINCEKR ddPTM_PC-9_AZD4547_30min_R2 1 ASEIDQVVPAAQSSPINCEKR 21 1 O94782;C9JWX4;C9JC88 O94782 USP1 Ubiquitin carboxyl-terminal hydrolase 1 1 ASEIDQVVPAAQS(0.584)S(0.416)PINCEKR 92.88600000000001 0.0001847 19570000.0 27224.0 16690.0 45899.0 80052.0 60182.0 35932.0 32778.0 44832.0 34576.0 46631.0 True False 35880.66570562263 22084.716109261357 45290.34927012615 61597.24819107096 51826.768116936866 33685.166359762465 35695.17850060015 37904.244536871876 36403.61677169701 44998.46288337177 0.7973753636567344 0.4907882335114672 1.0064865857198477 1.368874495796009 1.1517452996397428 0.748584822709802 0.7932532849647749 0.8423453182192716 0.8089968954283813 1.0 15.457588100360383 -10.362607039153247 14.669229326953353 0.9999999610396597 0.8949243801830562 0.020229074130696967 0.22754648452871468 0.0 0.0 0.24647251340676915 0.05977836509338673 4.3390330772293135e-11 10.362607039153247 -0.10507558085660351 ASEIDQVVPAAQS(ph)SPINCEKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASEIDQVVPAAQSSPINCEKR 21 1 O94782;C9JWX4;C9JC88 O94782 USP1 Ubiquitin carboxyl-terminal hydrolase 1 1 ASEIDQVVPAAQS(0.584)S(0.416)PINCEKR 92.88600000000001 0.0001847 8941500.0 25710.0 12063.0 21221.0 34162.0 30421.0 41118.0 31037.0 28687.0 45891.0 29183.0 True False 30062.195204353415 13260.53491841033 21726.989121090668 32248.013894698346 24460.22342897571 38961.699695897885 28096.950671578983 27933.996646388954 46562.069057757595 34473.6468874991 0.8720340874424466 0.3846571545413982 0.6302492217314366 0.9354395837474389 0.7095339668819758 1.1301879323369832 0.8150269324063755 0.8103000166344001 1.35065690060897 1.0 15.07320630570479 -6.247116998920604 0.7884434567253574 1.0221575045140356 0.5902303445758286 0.37357484229270355 0.20099379508370016 0.758571559884471 1.012750427313831 0.11024711538971667 0.19358168111802598 5.660867647364457e-07 6.247116998920604 -0.4319271599382071 ASEIDQVVPAAQS(ph)SPINCEKR ddPTM_PC-9_Lapatinib_30min_R1 2 ASEIDQVVPAAQSSPINCEKR 21 1 O94782;C9JWX4;C9JC88 O94782 USP1 Ubiquitin carboxyl-terminal hydrolase 1 1 ASEIDQVVPAAQS(0.59)S(0.41)PINCEKR;ASEIDQVVPAAQS(0.5)S(0.5)PINCEKR 92.71600000000001 0.00018529 30388000.0 163578.0 75588.0 95714.0 91094.0 65408.0 73809.0 56499.0 55686.0 90660.0 47715.0 True False 161245.34772346864 75412.98063011299 87844.76438672464 97793.35664067602 61560.83003707572 70652.3611271825 59424.241768269814 58273.374851737615 80448.91610787662 55962.47417375896 2.881311988151469 1.347563376057352 1.5697083748294214 1.7474809340458315 1.1000376760672574 1.2624953090496436 1.0618587302584648 1.0412937546471497 1.4375510964381102 1.0 15.772172126886025 -2.6642809172410336 1.1273504508462395 1.2417014928159762 199.99999999305422 0.7929315539489917 0.24248948374883883 89.37744840150245 1.2024379522919466 0.0756970690903917 44785.477687910156 0.0021663024094713784 2.6642809172410336 198.75829850023825 up ASEIDQVVPAAQSS(ph)PINCEKR ddPTM_PC-9_AZD4547_30min_R2 1 ASEIDQVVPAAQSSPINCEKR 21 1 O94782;C9JWX4;C9JC88 O94782 USP1 Ubiquitin carboxyl-terminal hydrolase 1 1 ASEIDQVVPAAQS(0.238)S(0.762)PINCEKR 101.58 7.59e-05 22132000.0 24321.0 21861.0 34979.0 72723.0 49332.0 40926.0 28733.0 32759.0 26069.0 46542.0 True False 32054.572091773705 28927.140734844997 34515.15560512743 55957.835909149806 42483.10333230417 38366.89075029605 31290.181336803467 27696.849276931353 27446.95411908171 44912.57874628224 0.7137103454436383 0.6440765937368831 0.768496411664728 1.2459279220029615 0.945906570457632 0.8542571328855609 0.6966908204840854 0.6166835672784439 0.6111195323282056 1.0 15.454831939290305 -7.2427755728119605 5.802502092063793 0.6986453872537267 0.8698543720956871 0.09787818887587774 0.18389135524348418 0.35890473040843235 44.982443056070906 0.07912849086787868 0.05848644018668732 5.717740318318248e-08 7.2427755728119605 0.17120898484196034 ASEIDQVVPAAQSS(ph)PINCEKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASEIDQVVPAAQSSPINCEKR 21 1 O94782;C9JWX4;C9JC88 O94782 USP1 Ubiquitin carboxyl-terminal hydrolase 1 1 ASEIDQVVPAAQS(0.267)S(0.733)PINCEKR 76.241 0.00062016 12078000.0 16818.0 17095.0 24757.0 28091.0 30596.0 41451.0 34592.0 35276.0 43927.0 30855.0 True False 19664.955229358853 18792.07862308087 25347.300771445334 26517.152342250793 24600.93343522375 39277.236589684915 31315.195335607797 34350.042378011545 44569.34927328059 36448.767251954414 0.5395231913722515 0.515575149446878 0.695422717488098 0.727518496275863 0.6749455548158388 1.0776012345816397 0.8591565009356702 0.9424198667835513 1.2227944216931161 1.0 15.153582400972251 -6.353430240118014 0.5670211885423265 1.0760057357690478 0.4793233078445336 0.7696355425566193 0.10664194274527224 0.4841379796342833 0.32573839907758706 0.08101768273289418 0.14896054179800217 4.4316939421438705e-07 6.353430240118014 -0.5966824279245142 ASEKPVS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 ASEKPVSPK 9 1 B1ALK7;A0A2R8YG42;Q14155-1;Q14155-5;Q14155-6;Q14155-2;Q14155-3;Q14155;E7EUY6;E7EU80 B1ALK7 ARHGEF7 Rho guanine nucleotide exchange factor 7 1 ASEKPVS(1)PK 96.745 0.024162 16299000.0 18684.0 16936.0 9952.1 17102.0 13180.0 12699.0 15431.0 12023.0 12633.0 14784.0 True False 24625.12334865755 22410.23079846916 9820.128651413375 13159.398123266075 11350.184503360273 11904.92952250427 16804.329106191974 10165.121611054843 13300.754589219341 14266.416659899385 1.7260902955312412 1.5708380970997948 0.6883388369706168 0.9224038829774991 0.7955876218913349 0.8344722999691382 1.177894176708455 0.7125210102427033 0.9323122201109991 1.0 13.800335393677823 -5.184551074306804 5.433657163310787 0.8803971372631214 1.6765889119275164 0.8322670367623173 0.13775084525851206 0.07736617833817953 4.0126035780549385 0.03420830061981029 0.09460497645101239 6.538060359729744e-06 5.184551074306804 0.796191774664395 ASEPLLS(ph)PPPFGESR ddPTM_PC-9_AZD4547_30min_R2 4 ASEPLLSPPPFGESR 15 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 ASEPLLS(0.999)PPPFGES(0.001)R;ASEPLLS(1)PPPFGESR;ASEPLLS(1)PPPFGESR;ASEPLLS(1)PPPFGESR 197.73 8.390200000000001e-10 54034900.0 95986.9 103429.6 148691.0 174332.0 152485.0 129667.0 121595.0 158196.0 108468.0 124814.0 True False 126508.73754845087 136861.19552393397 146719.26018702652 134142.45080255083 131315.08983269302 121558.90199185439 132416.71943927254 133750.44318243652 114201.39703818908 120444.29985042512 1.0503505579388723 1.1363028029877407 1.2181503015853072 1.113730172113889 1.0902557447365122 1.009254087929553 1.0994021269891185 1.1104754923938764 0.948167718854368 1.0 16.878006592611655 -6.4116711243241955 2.759226784973562 1.0446788425343625 1.1372171906153699 0.3621226663866346 0.05891271045917975 0.3342482444438227 4.937328180140566 0.020220123298460905 0.02309197855089808 3.875510123476606e-07 6.4116711243241955 0.09253834808100736 ASEPLLS(ph)PPPFGESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ASEPLLSPPPFGESR 15 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 ASEPLLS(1)PPPFGESR;AS(0.346)EPLLS(0.654)PPPFGESR;ASEPLLS(1)PPPFGESR;ASEPLLS(1)PPPFGESR 192.4 3.8960000000000006e-08 34854600.0 60594.0 67037.0 73744.0 79302.0 111336.0 113057.0 125901.0 122736.0 109754.0 100335.0 True False 70851.36741394766 73691.99032790124 75502.33663567736 74858.9660405528 89520.51003216335 107128.09189452612 113974.7458356947 119514.31004954163 111358.94461583158 118524.9412485769 0.5977760180058166 0.6217424750572154 0.6370164443054208 0.6315882990699362 0.7552883729713572 0.9038442944245069 0.9616098066369062 1.0083473469005124 0.9395401798367788 1.0 16.854831152374288 -6.659602780965184 1.536410904934063 0.9819590687626032 0.6156106267548412 0.9856699256356892 0.019635622542435175 0.03932386507748361 0.19237524473982745 0.008099073890833227 0.007989714432516972 2.1897635331022198e-07 6.659602780965184 -0.36634844200776195 ASEPLLS(ph)PPPFGESR ddPTM_PC-9_Lapatinib_30min_R1 2 ASEPLLSPPPFGESR 15 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 AS(0.025)EPLLS(0.975)PPPFGESR;ASEPLLS(1)PPPFGESR 137.27 4.0024e-05 36729000.0 56330.0 54353.0 70913.0 56974.0 93965.0 119454.0 108332.0 99053.0 107143.0 87719.0 True False 55526.72387034312 54227.14896793837 65082.80687209598 61164.058019692435 88438.1634422978 114345.23088087447 113940.90088745313 103655.36399075449 95075.42707419174 102881.1122717797 0.5397173751743556 0.5270855628454639 0.632602092210741 0.5945120213914109 0.8596151566545261 1.1114307413280113 1.1075006711286026 1.0075256935104808 0.92412907456747 1.0 16.65061861961331 -6.396299681359229 2.643290710768806 1.0348030381131972 0.5678356935910308 0.9303769821912332 0.058812324271121874 0.07228442898641818 0.9826486216978182 0.021539988583685454 0.024880900755553124 4.0151365401828074e-07 6.396299681359229 -0.46696734452216637 ASES(ph)SSEEKDDYEIFVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASESSSEEKDDYEIFVK 17 1 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 AS(0.065)ES(0.744)S(0.173)S(0.017)EEKDDY(0.002)EIFVK 55.413999999999994 0.024681 7940000.0 12324.0 11491.0 13863.0 16809.0 16122.0 17076.0 15860.0 16255.0 10858.0 13645.0 True False 14410.209789904766 12631.75053862664 14193.546495720275 15867.246225513267 12963.009832745356 16180.504499420023 14357.625983543592 15828.323473596147 11016.777708682137 16118.730486239432 0.8940040161479695 0.7836690705518261 0.8805623065561715 0.9843980106906771 0.8042202730427116 1.0038324366322353 0.890741736503424 0.9819832577453165 0.6834767612801247 1.0 13.9764505010003 -5.514352244207898 24.534433876689718 0.9073728994181147 0.8371563174551815 0.07052717811595777 0.09824605968223506 765.1290472897617 2201602.674166641 0.024718219009814125 0.04574078257107177 3.0594809669477887e-06 5.514352244207898 -0.07021658196293323 ASES(ph)SSEEKDDYEIFVK ddPTM_PC-9_Lapatinib_30min_R1 1 ASESSSEEKDDYEIFVK 17 1 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 AS(0.026)ES(0.58)S(0.261)S(0.133)EEKDDYEIFVK 86.213 0.0014643 6229700.0 51806.0 47506.0 50810.0 52549.0 44447.0 45508.0 44315.0 42171.0 41501.0 40885.0 True False 51067.23693994317 47396.00277575991 46632.5979322719 56413.62875832514 41832.71484616417 43561.728924329356 46609.41386503968 44130.41861280441 36826.720355095815 47951.917774161935 1.0649675614738368 0.9884068244982358 0.9724866094385712 1.1764624102004666 0.8723887758396393 0.9084460214811647 0.9720031237239558 0.9203056032220536 0.7679926489809602 1.0 15.549300894645738 -6.296053765124095 24.98557869839621 0.9062081502646299 1.0405617599456376 0.45042690645395167 0.07745703650768407 601.2349406100726 433985.7723161216 0.023871941437515243 0.027069366177771666 5.057620454064798e-07 6.296053765124095 0.13435360968100774 ASESSKPWPDATYGT(ph)GSASR ddPTM_PC-9_AZD4547_30min_R2 1 ASESSKPWPDATYGTGSASR 20 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 ASESSKPWPDAT(0.046)Y(0.002)GT(0.55)GS(0.316)AS(0.086)R 59.55 0.010956 22340000.0 20650.0 14017.0 21963.0 27591.0 24386.0 22281.0 20623.0 24796.0 22439.0 21776.0 True False 27216.270453317175 18547.721132625313 21671.756269630718 21230.32122670065 21000.424833000256 20887.765547753184 22458.407047955225 20964.347955395155 23625.079729873567 21013.628868098538 1.2951723200286964 0.8826519802480761 1.0313190741905272 1.0103119913253573 0.999371644222844 0.9940103957705073 1.0687543398108668 0.9976548118836248 1.1242741497990172 1.0 14.35903770376576 -10.83358328099266 14.754080971385815 1.0000062154289917 1.0351363635085467 0.009087776445125928 0.1024461064989538 0.0 0.0 0.09151004701790927 0.022194446450592847 1.4669547543841442e-11 10.83358328099266 0.035130148079554946 ASESSKPWPDATYGT(ph)GSASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASESSKPWPDATYGTGSASR 20 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 ASESSKPWPDAT(0.151)Y(0.12)GT(0.345)GS(0.345)AS(0.039)R;ASESSKPWPDAT(0.017)YGT(0.712)GS(0.254)AS(0.017)R;ASESSKPWPDAT(0.081)Y(0.001)GT(0.419)GS(0.419)AS(0.081)R 79.589 0.009626000000000001 40728000.0 71248.0 65719.0 75696.0 68289.0 71451.0 58320.0 55492.0 55536.0 54748.0 42648.0 True False 83308.87918785575 72243.1479982599 77500.87971867854 64462.98872592508 57450.68946529512 55261.596533507625 50235.396032711265 54078.238845255924 55548.5859269598 50379.74479861775 1.6536185230962397 1.4339720911059877 1.538334106861234 1.2795417877482724 1.140352927450148 1.0969010810674813 0.9971347856865197 1.0734123219842044 1.1025976044341508 1.0 15.620556193588632 -5.998000098662585 1.250794451470585 1.0491249768761666 1.570765699738169 0.9271868249939031 0.059864510825110136 0.10937823083110049 0.34773879318248085 0.021388518057617305 0.040688144781686815 1.004615562050813e-06 5.998000098662585 0.5216407228620024 ASESSKPWPDATYGTGS(ph)ASR ddPTM_PC-9_AZD4547_30min_R2 1 ASESSKPWPDATYGTGSASR 20 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 ASESSKPWPDAT(0.005)YGT(0.096)GS(0.803)AS(0.096)R 86.91799999999999 0.00035082 19860000.0 28647.0 23771.0 34051.0 46511.0 30805.0 30667.0 25778.0 47585.0 33373.0 36225.0 True False 37756.1501053839 31454.510882759256 33599.461491471826 35788.60753778674 26528.25748300555 28749.387642069338 28072.192061396967 40231.8316445184 35137.028647670144 34956.77377603185 1.0800810837775725 0.8998116097408874 0.9611716946976764 1.0237960678832791 0.7588874663598012 0.822426801348052 0.8030544306306865 1.150902308728027 1.0051565076569478 1.0 15.093284421593419 -7.763456983251993 24.999861538363824 1.0585220432797848 0.90437619879011 0.302595069957841 0.10066555500048924 67.47463486187232 836024.8229396798 0.054303086033393407 0.028131000311082097 1.7240228465550736e-08 7.763456983251993 -0.15414584448967483 ASESSKPWPDATYGTGS(ph)ASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASESSKPWPDATYGTGSASR 20 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 ASESSKPWPDAT(0.006)Y(0.001)GT(0.099)GS(0.759)AS(0.135)R;ASESSKPWPDAT(0.012)YGT(0.121)GS(0.494)AS(0.372)R 60.17100000000001 0.006644800000000001 20469200.0 46741.0 64562.0 45262.0 44339.0 59537.0 38150.0 54284.0 42843.0 45759.0 33845.0 True False 54653.3281231693 70971.28868460633 46341.21773709087 41854.82957897754 47871.15223993054 36149.346840763304 49141.82653787391 41718.41664591076 46428.13880747708 39980.83058312739 1.366988312299694 1.7751329236906213 1.1590859184563231 1.046872437828768 1.1973526197860682 0.9041669798630687 1.2291347083372655 1.0434604793707478 1.1612599871066853 1.0 15.287020823260605 -5.376882618171626 5.877742501001354 1.0898934436159575 1.5672952314855364 0.6883977043000976 0.12933279149015842 0.10726863827150208 4.743826738504265 0.0310593366161219 0.06587031204471575 4.198724524745819e-06 5.376882618171626 0.4774017878695789 ASESSKPWPDATYGTGS(ph)ASR ddPTM_PC-9_Lapatinib_30min_R1 2 ASESSKPWPDATYGTGSASR 20 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 ASESSKPWPDAT(0.007)YGT(0.334)GS(0.614)AS(0.046)R;ASESSKPWPDATYGT(0.002)GS(0.984)AS(0.014)R 131.94 1.9831e-05 39808000.0 111682.0 94132.0 122688.0 105212.0 94552.0 100904.0 90880.0 79175.0 94147.0 63077.0 True False 110089.39420002962 93914.04313745297 112601.06622937582 112949.6414569431 88990.63725638427 96588.57113871258 95585.32172074476 82853.75954254808 83543.17344813881 73979.77540518066 1.4881012222202594 1.2694556400461356 1.5220520150631682 1.52676377886156 1.2029049394782623 1.3056077909091446 1.2920466600125837 1.1199514879406622 1.1292704389893087 1.0 16.174843300147558 -7.57148228744575 0.5564038510504761 1.0034437731972417 1.445301028714515 0.7072517584770885 0.09309775204727312 0.4795411492521104 0.3145891688364337 0.09272201920079758 0.061999545625496706 2.6823640046905952e-08 7.57148228744575 0.4418572555172733 ASET(ph)PPPVAQPKPEAPHPGLETTLQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASETPPPVAQPKPEAPHPGLETTLQER 27 1 Q6P1N0;Q6P1N0-2 Q6P1N0 CC2D1A Coiled-coil and C2 domain-containing protein 1A 1 AS(0.085)ET(0.915)PPPVAQPKPEAPHPGLETTLQER;AS(0.265)ET(0.735)PPPVAQPKPEAPHPGLETTLQER 76.028 0.00046988 13406000.0 31955.2 27131.5 30545.4 32590.6 41503.0 28947.4 33815.7 31505.7 29775.4 26286.6 True False 37364.58421603088 29824.93601416314 31273.7181800746 30764.65434215081 33370.78508177838 27429.347385014702 30612.432091533097 30678.708758048495 30210.808895477443 31052.15249538891 1.2032848357800425 0.9604788595119773 1.0071352762008556 0.9907414420536292 1.0746689810548165 0.8833315947771357 0.9858392939452069 0.9879736602029161 0.972905466053073 1.0 14.922405657231588 -4.757525230678294 24.995594444294575 0.9849660541392643 1.2032851509914821 0.6836564967544305 0.04458915281827228 65.41086762777822 417652.868665442 0.010901195174497147 0.08033594964994903 1.7477317236245342e-05 4.757525230678294 0.21831909685221784 ASET(ph)PPPVAQPKPEAPHPGLETTLQER ddPTM_PC-9_Lapatinib_30min_R1 1 ASETPPPVAQPKPEAPHPGLETTLQER 27 1 Q6P1N0;Q6P1N0-2 Q6P1N0 CC2D1A Coiled-coil and C2 domain-containing protein 1A 1 AS(0.08)ET(0.92)PPPVAQPKPEAPHPGLETTLQER 88.829 3.212e-07 19368000.0 54832.0 51947.0 62403.0 50985.0 58406.0 59416.0 60445.0 58605.0 65264.0 48029.0 True False 54050.085625042695 51826.71991311417 57272.46622254599 54734.606980974124 54970.67391061406 56874.91618546087 63574.54634034359 61328.00224807098 57913.28105961241 56330.74865538029 0.9595129998308701 0.9200431584919841 1.0167176469272037 0.9716648240524722 0.9758555535434673 1.0096602218694035 1.1285940247178206 1.088712713961301 1.0280935801850197 1.0 15.781635025176744 -7.013268953706885 4.639925817144766 1.0694122762344922 0.970187121257331 0.5496201804715627 0.03913708259659567 0.1416462633307632 7.940738482658721 0.014923380610083779 0.012174479013106067 9.699091273621012e-08 7.013268953706885 -0.09922515497716122 ASFDHS(ph)PDSLPLR ddPTM_PC-9_AZD4547_30min_R2 1 ASFDHSPDSLPLR 13 0 H0Y6H0;Q8NB78;Q8NB78-2 H0Y6H0 KDM1B Lysine-specific histone demethylase 1B 1 AS(0.002)FDHS(0.996)PDS(0.002)LPLR 88.311 0.0037775999999999994 4142600.0 11952.0 11557.0 29459.0 47647.0 35780.0 26211.0 22241.0 38928.0 19869.0 29892.0 True False 15752.487382956275 15292.574240547248 29068.35441183135 36662.720288811775 30812.56460775646 24572.02202648707 24220.405913473893 32912.57207644872 20919.23477663255 28845.49017841668 0.5460987934517022 0.5301547710217019 1.0077261378481073 1.2710035455124369 1.068193482488005 0.8518496955504267 0.8396600565171378 1.1409954163675537 0.7252168240942266 1.0 14.816058159223758 -5.261145101265718 24.747313507851104 0.9959156408091782 0.538126733404587 0.5944322458238913 0.14855218559136477 14.789571035446194 1243556.059240681 0.03991341516366959 0.09313151736152696 5.480938117925653e-06 5.261145101265718 -0.4577889074045911 ASFDHS(ph)PDSLPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASFDHSPDSLPLR 13 0 H0Y6H0;Q8NB78;Q8NB78-2 H0Y6H0 KDM1B Lysine-specific histone demethylase 1B 1 AS(0.02)FDHS(0.95)PDS(0.03)LPLR 56.339 0.041806 1615700.0 15463.0 20838.0 21245.0 21686.0 21850.0 20615.0 16851.0 20075.0 19460.0 13668.0 True False 18080.580491828747 22906.658926455657 21751.561372111173 20471.003726960607 17568.649351537406 19533.91310936659 15254.751289324913 19548.052521220707 19744.56568529697 16145.900204171523 1.1198248634757058 1.418729128558431 1.3471878989126507 1.2678762700187898 1.0881182919115464 1.209837349565664 0.9448064893516207 1.210713077253518 1.2228841647488742 1.0 13.978880259268065 -6.158163583478718 4.350516524037331 1.1198309463444385 1.3073976646180365 0.3748823746845702 0.11069794242283162 0.24416548937262833 7.827744131644829 0.03280118605390721 0.04300203343866307 6.947625756355191e-07 6.158163583478718 0.18756671827359805 ASFGATGGPPAHLLTPS(ph)PLSGPGGSSLLEK ddPTM_PC-9_AZD4547_30min_R2 1 ASFGATGGPPAHLLTPSPLSGPGGSSLLEK 30 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 ASFGATGGPPAHLLT(0.061)PS(0.902)PLS(0.032)GPGGS(0.004)S(0.002)LLEK 85.595 6.7010999999999995e-09 4234700.0 9416.0 7133.6 14725.0 14622.0 14260.0 13973.0 7728.6 18429.0 11784.0 11166.0 True False 12410.092135033156 9439.396694848821 14529.736878855918 11251.123807648037 12280.245145517256 13099.266101106556 8416.430427717927 15581.221506290425 12406.87818248719 10775.081738665884 1.1517399529787429 0.8760394513738102 1.3484572304186453 1.0441799032738561 1.1396892797063582 1.2156999286697237 0.7811013068713859 1.4460420704167776 1.1514416765828959 1.0 13.395411193042072 -5.241180025391247 24.859861084500377 1.1430909788598989 1.0138897681048316 0.07064570575833495 0.1840131524445781 2108.1528785752234 2586863.733462373 0.04470403804653408 0.1179479862464333 5.738785265983548e-06 5.241180025391247 -0.1292012107550673 ASFNHFDR ddPTM_PC-9_AZD4547_30min_R2 2 ASFNHFDR 8 0 P12814-4;P12814-3;P12814;P12814-2;H9KV75;P35609-2;P35609;A0A494C1A0;H7C5W8;Q08043;H0YJ11;A0A087WSZ2;H0YJW3;A0A494C060;F6THM6 P12814-4 ACTN1;ACTN2;ACTN3 Alpha-actinin-1;Alpha-actinin-2;Alpha-actinin-3 0 ; 100.02 0.0042148 2344000.0 8451.7 8057.799999999999 19975.2 28132.0 20512.6 20588.0 12749.2 25222.0 17028.7 16278.4 False True 11139.164793719165 10662.326271132786 19710.31579643619 21646.602035067317 17664.779563249445 19300.62910538765 13883.85410152697 21324.519443901307 17928.802317219936 15708.498170759347 0.7091171079902605 0.6787616585129838 1.2547549474287774 1.3780185603841797 1.1245365006396109 1.2286743707501515 0.8838435062730013 1.3575148440094629 1.141344138842858 1.0 13.939257636237032 -5.257262931911962 24.949491999437956 1.181380304073594 0.6939393220405766 0.6404428032402925 0.142839899708087 197.95117928121675 1182520.0123867495 0.03627188083266241 0.08903833380367247 5.530151996679195e-06 5.257262931911962 -0.48744098203301733 ASFNHFDR ddPTM_PC-9_Lapatinib_30min_R1 1 ASFNHFDR 8 0 P12814-4;P12814-3;P12814;P12814-2;H9KV75;P35609-2;P35609;A0A494C1A0;H7C5W8;Q08043;H0YJ11;A0A087WSZ2;H0YJW3;A0A494C060;F6THM6 P12814-4 ACTN1;ACTN2;ACTN3 Alpha-actinin-1;Alpha-actinin-2;Alpha-actinin-3 0 84.213 0.014216999999999999 0.0 5797.6 6442.8 9197.7 8219.7 11435.0 11382.0 7597.3 9902.3 9214.3 7308.8 False True 5714.925160850373 6427.882092444453 8441.500610148732 8824.204158115383 10762.415782074992 10895.21839273791 7990.651020125609 10362.397008123435 8176.488503119431 8572.116341636161 0.6666877738338727 0.7498594088397034 0.9847627206302594 1.02940788557136 1.255514432276215 1.2710068270793369 0.9321678220014022 1.2088493197171846 0.9538471221400598 1.0 13.065435715213473 -5.316844325857976 1.7000240277088823 1.111678528426384 0.6534939618022926 0.6436817191373365 0.11381926598065598 0.26573065635734866 1.3461216586848366 0.03344811916050271 0.1391090331663675 4.821205842052485e-06 5.316844325857976 -0.45818456662409135 ASGDPGASGMS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 5 ASGDPGASGMSPR 13 0 Q8NDT2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 ASGDPGAS(0.002)GMS(0.998)PR;ASGDPGAS(0.006)GMS(0.994)PR;ASGDPGAS(0.011)GMS(0.989)PR;ASGDPGAS(0.037)GMS(0.963)PR;ASGDPGAS(0.008)GMS(0.992)PR 131.08 7.2653e-05 126748300.0 101409.0 91685.0 121322.0 176987.0 140599.0 131913.0 109167.0 146764.0 111472.0 115792.0 True False 133654.9525617648 121320.3832521047 119713.19100961344 136185.38157189186 121079.25576539857 123664.45925680004 118882.6515154988 124084.99610121048 117364.18234540161 111738.15732434184 1.1961442336462125 1.085756076144594 1.0713725183611404 1.2187902936020967 1.083598107081204 1.1067343709440256 1.0639396099079983 1.1104979630282386 1.0503500787535733 1.0 16.76976240853162 -8.722220989756929 0.2345080971959198 0.9646755260958135 1.157524050034979 0.4516085003395701 0.045979321904624816 3.6987096041994425 0.6075407652094335 0.2411630189522628 0.124773172062664 1.8957410322392066e-09 8.722220989756929 0.19284852393916552 ASGDPGASGMS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASGDPGASGMSPR 13 0 Q8NDT2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 ASGDPGASGMS(1)PR 98.0 0.0025269000000000003 59512000.0 22238.0 21690.0 24784.0 29608.0 29346.0 25152.0 28480.0 21654.0 21270.0 17321.0 True False 26002.454179479257 23843.239855783817 25374.944553843416 27949.159750431132 23595.861962023653 23832.98484243455 25782.16822265583 21085.60544430951 21581.03351111338 20461.160187039448 1.2708201266099166 1.1652926636528975 1.24015179598254 1.3659616314491663 1.1532025430781678 1.1647914695243378 1.2600540725440792 1.0305185654949125 1.0547316630062495 1.0 14.320600330528766 -7.766739219255749 24.954451278404658 1.0319687580005974 1.228854736995298 0.6999991920112447 0.06088528205518214 76.40533092699899 359747.95490588306 0.033197500627070914 0.016687541466768322 1.7110424360840438e-08 7.766739219255749 0.19688597899470062 ASGDPGASGMS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 ASGDPGASGMSPR 13 0 Q8NDT2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 ASGDPGAS(0.016)GMS(0.984)PR;ASGDPGASGMS(1)PR;ASGDPGASGMS(1)PR;ASGDPGAS(0.011)GMS(0.989)PR 164.92 0.00029435 95478000.0 127252.0 106853.0 130367.0 99943.0 130504.0 107144.0 101229.0 100472.0 115250.0 83910.0 True False 125437.36314484102 106605.58844352895 119648.72849117311 107293.14162007468 122828.01130073593 102561.70088486299 106470.14230269897 105140.29591106903 102269.33136369714 98413.73169695327 1.2745920816324898 1.0832389607153703 1.215772701919373 1.0902253148012302 1.2480779783756386 1.0421482766315846 1.0818626676057148 1.0683498542137286 1.039177456237677 1.0 16.586572008822706 -7.19958622195369 0.44605987588790236 0.9976505567543515 1.2011779263291924 0.5010899108074109 0.06415943703246327 0.9371447160377607 0.4177229338183769 0.06227586041962604 0.06708429376572231 6.315587813372408e-08 7.19958622195369 0.20352736957484086 ASGEMAS(ph)AQYITAALR ddPTM_PC-9_AZD4547_30min_R2 1 ASGEMASAQYITAALR 16 0 A6NJA2;P54578-2;P54578-3;P54578 A6NJA2 USP14 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 14 1 AS(0.063)GEMAS(0.665)AQY(0.272)ITAALR 97.45200000000001 0.0019250999999999997 40715000.0 22591.0 36807.0 32027.0 14863.0 22664.0 30683.0 40357.0 48234.0 42071.0 22032.0 True False 29774.468078009137 48704.142949885165 31602.301053929954 11436.56498106092 19517.494809116615 28764.387159539998 43948.69481813165 40780.54360705475 44294.78717035122 21260.66638601887 1.4004484872397502 2.2908098017996874 1.486421002998843 0.5379212849406106 0.9180095512881677 1.3529391147615022 2.0671362797467414 1.918121608543383 2.0834148077070487 1.0 14.375899196396729 -7.235519660031881 17.630320961773617 1.8436755334333423 1.3269421858340988 0.14391006055532984 0.5074518216808116 35.95327254680868 24454.16682943847 0.21018694161848764 0.16249247323737764 5.814071120544224e-08 7.235519660031881 -0.5167333475992435 ASGEMAS(ph)AQYITAALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASGEMASAQYITAALR 16 0 A6NJA2;P54578-2;P54578-3;P54578 A6NJA2 USP14 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 14 1 AS(0.043)GEMAS(0.773)AQY(0.179)IT(0.005)AALR 60.691 0.039159 5037800.0 19695.0 39339.0 31263.0 22214.0 28385.0 12136.0 23931.0 11535.0 19108.0 15548.0 True False 23028.974506018705 43244.315937606225 32008.42848558773 20969.421598759713 22823.16301342742 11499.566795793005 21664.082434563785 11232.218472342753 19387.418351215543 18366.729322099724 1.2538418845378827 2.3544919282701358 1.7427397074488198 1.1417069000700253 1.2426362153639137 0.6261085789485763 1.1795285951373242 0.6115524585440268 1.0555727158175996 1.0 14.164807119177995 -5.864996198210149 2.2372988906805875 0.9290286954050406 1.8648204334526102 0.5816954727048407 0.31473586180127516 0.1915835108644811 1.953003985025463 0.09190748461025297 0.15891724817797076 1.36459508212644e-06 5.864996198210149 0.9357917380475695 ASGGAQS(ph)PLR ddPTM_PC-9_AZD4547_30min_R2 4 ASGGAQSPLR 10 0 H7BZV9;C9JU48;D3YTC9;Q6NXT1 H7BZV9 ANKRD54 Ankyrin repeat domain-containing protein 54 1 ASGGAQS(1)PLR;AS(0.008)GGAQS(0.992)PLR;ASGGAQS(1)PLR;ASGGAQS(1)PLR 99.73200000000001 0.0042602 331833000.0 364211.0 369552.0 489102.0 727788.0 563230.0 510211.0 440494.0 576884.0 419434.0 511261.0 True False 480022.52194058715 489002.4570167613 482616.1879064301 560007.7208125122 485035.2365574807 478307.4255143269 479697.11265005055 487739.83327553596 441604.42494851834 493361.9080057374 0.9729622699914742 0.9911637868302443 0.9782193965019643 1.1350850394514036 0.9831225894963909 0.9694859245370937 0.972302694768385 0.9886045626162608 0.8950922594197986 1.0 18.91228680529033 -6.50943223665683 24.979393867134316 0.9661095492114717 1.0199926392660938 0.2095388050603202 0.04978154422340193 1052.7517983554176 1955685.7305606161 0.01609676116127291 0.017460148192678892 3.094338090031993e-07 6.50943223665683 0.05388309005462211 ASGGAQS(ph)PLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ASGGAQSPLR 10 0 H7BZV9;C9JU48;D3YTC9;Q6NXT1 H7BZV9 ANKRD54 Ankyrin repeat domain-containing protein 54 1 ASGGAQS(1)PLR;AS(0.001)GGAQS(0.999)PLR;AS(0.01)GGAQS(0.99)PLR;AS(0.008)GGAQS(0.992)PLR 80.318 0.017819 258251000.0 270855.0 255926.0 297117.0 321529.0 391348.0 337295.0 341430.0 317517.0 324100.0 240575.0 True False 316705.40186990047 281332.64192398917 304201.39610249735 303514.7725410826 314666.1687151237 319606.6564260876 309087.2786608628 309182.51518707094 328839.3493630389 284189.3431093477 1.1144168827894492 0.9899478947588146 1.0704180275523196 1.0680019497574864 1.1072412683471016 1.1246257615758393 1.0876103772193004 1.087945493677807 1.157113584081551 1.0 18.116492930032422 -5.9863341270563035 2.457874841394279 1.099438463021705 1.0509130462065748 0.09695836334785757 0.04725259190994245 0.5102934874548656 6.211613351590381 0.013791887225995227 0.02123800249832641 1.0319671501708047e-06 5.9863341270563035 -0.04852541681513012 ASGGAQS(ph)PLR ddPTM_PC-9_Lapatinib_30min_R1 4 ASGGAQSPLR 10 0 H7BZV9;C9JU48;D3YTC9;Q6NXT1 H7BZV9 ANKRD54 Ankyrin repeat domain-containing protein 54 1 ASGGAQS(1)PLR;AS(0.004)GGAQS(0.996)PLR;ASGGAQS(1)PLR;ASGGAQS(1)PLR 104.94 0.0025326999999999997 280268000.0 583723.0 438701.0 552284.0 461061.0 538050.0 558327.0 427275.0 453703.0 573196.0 360645.0 True False 575399.0029783132 437685.21478820906 506877.3413978923 494968.9639944086 506402.95684700046 534448.6557338063 449397.2088273682 474783.6977042322 508636.6304585308 422982.0077207439 1.3603391928627762 1.034760833319351 1.1983425586568608 1.1701891687109092 1.1972210344732481 1.2635257433612959 1.0624499402444179 1.1224678332362736 1.2025018113638932 1.0 18.69023677153116 -14.522878735693082 0.17447558880633193 0.30941022455098005 1.2113824189988391 0.2938530594746943 0.08725426192842371 177.46904497147125 1.68504458018805 42.386245992886565 0.2845170350259781 3.0000000662264162e-15 14.522878735693082 0.9019721944478591 ASGPPVSELITK ddPTM_PC-9_Lapatinib_30min_R1 2 ASGPPVSELITK 12 0 P10412;P16402;P16403 P10412;P16402;P16403 HIST1H1E;HIST1H1D;HIST1H1C Histone H1.4;Histone H1.3;Histone H1.2 0 ; 155.0 0.00028137 11720900.0 54046.0 52168.0 63941.0 50811.0 46636.0 59031.0 53878.0 57495.0 59994.0 53594.0 False True 53275.294129177455 52047.20820119239 58684.017799397734 54547.81044052712 43892.96216990375 56506.381737982054 56667.53921292133 60166.42759581682 53236.843955172604 62857.651490483884 0.8475546391872895 0.8280170666107673 0.9336018194743085 0.8677990530522 0.6982914749296476 0.898957889741341 0.9015217379144417 0.9571854208540628 0.8469429368234066 1.0 15.939800750217344 -6.98109333886229 24.996943408021355 0.9196154380861582 0.837622976761955 0.3033950653757105 0.0657332248451538 341.5074564509853 451513.55281546724 0.0235474810801448 0.020764151454936514 1.04449571137484e-07 6.98109333886229 -0.08199246132420324 ASGQAFELILS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 13 ASGQAFELILSPR 13 0 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR 192.4 5.3927e-06 2839010900.0 1073864.0 988304.2 1194148.1 1628105.1999999997 1161258.5 1161986.2000000002 843782.4 1253094.5999999999 898179.1 841787.0 True False 1415330.4142412138 1307754.2053080103 1178312.915951492 1252770.7001145906 1000037.8020557938 1089327.0192237606 918877.3989768991 1059457.6228192714 945655.0135570246 812316.2933500223 1.7423390689411622 1.609907638211692 1.4505592533323273 1.5422203276855597 1.231094107360079 1.3410133812918315 1.1311817902696681 1.304242733393946 1.1641463076618943 1.0 19.631682056524433 -1.5228787452803376 0.18378435045596975 0.9911503420073664 4.325114098872391 0.8804543967110399 0.0765163849034625 17.20390255477622 0.19663754986381365 0.16058496464038333 16.109941473557576 0.029999999999999995 1.5228787452803376 3.3339637568650247 ASGQAFELILS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 12 ASGQAFELILSPR 13 0 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;AS(0.277)GQAFELILS(0.723)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR 177.39 6.5688e-05 1088551550.0 379907.80000000005 372880.10000000003 389643.7 376102.1 583011.0 698661.4 931806.0 779344.1 767105.3 668618.0 True False 444218.68701892125 409897.1720492695 398934.2835399609 355030.3186764605 468774.1797294826 662022.3662608988 843538.5899887672 758887.1431583316 778322.763791852 789833.1506228255 0.5624209197456844 0.518966786499204 0.5050867809554208 0.4495004019475508 0.5935103880608572 0.8381800203484228 1.0679959296765298 0.9608195636760861 0.9854268122047082 1.0 19.59118839583784 -6.8354153657410865 2.4727533165396878 0.9993665983502101 0.5097193885898351 0.9710096625598912 0.03936664862452571 0.04331054413686496 0.5407921428325994 0.015453049857123877 0.013662619275855926 1.4607793948628914e-07 6.8354153657410865 -0.489647209760375 ASGQAFELILS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 17 ASGQAFELILSPR 13 0 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;AS(0.001)GQAFELILS(0.999)PR 173.19 9.0319e-05 1354943000.0 425810.1 365711.89999999997 472515.19999999995 334165.80000000005 745195.3999999999 1017920.3999999999 1224656.1 1098575.4 1171866.5 1038669.3 True False 419737.969889991 364865.1165648217 433666.8242174179 358741.4676764295 701364.4716825263 974386.3173803487 1288062.8005696828 1149619.2236306716 1039878.5544686859 1218201.9045651557 0.34455533874724886 0.2995112018767221 0.3559892843643335 0.29448440880946114 0.5757374611336553 0.7998561763274878 1.0573475511265633 0.9437017125999609 0.8536175740423559 1.0 20.216321834403104 -6.664785438828703 1.9153233131349867 0.9585934706877652 0.3215157692682063 0.9613318572300823 0.058102207661598695 0.05839323968380985 0.4400638485576583 0.022901303048537946 0.02248007881056265 2.1637872687494135e-07 6.664785438828703 -0.637077701419559 down ASGQAFELILSPR ddPTM_PC-9_AZD4547_30min_R2 1 ASGQAFELILSPR 13 0 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 0 93.766 0.024928 0.0 4743.5 5128.2 5436.3 6333.0 6224.5 5135.7 4081.0 5160.3 4193.3 6924.4 False True 6251.834329070703 6785.790362583234 5364.211109984681 4873.024693874641 5360.335617690894 4814.563867133251 4444.201094055438 4362.894206897307 4414.949277208381 6681.978863623326 0.9356261755190024 1.0155360412055563 0.8027877997620482 0.7292786752743823 0.8022078080600562 0.7205296462914187 0.6651025369519883 0.6529344518955142 0.6607248192961748 1.0 12.706059703821944 -5.419236692116184 3.4421944473047237 0.7315539298095245 0.9753439941818456 0.44834976775158353 0.0983607138177099 0.19377070438768204 4.220355383793443 0.025787646975597597 0.058965974239539434 3.808581976789992e-06 5.419236692116184 0.2437900643723211 ASGQAFELILSPR ddPTM_PC-9_Lapatinib_30min_R1 2 ASGQAFELILSPR 13 0 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 0 ; 164.22 0.00020529 6629000.0 28125.0 19795.7 28366.0 24724.0 23922.0 29225.0 24392.0 20662.3 26762.0 21573.0 False True 27723.932342506683 19749.86427289418 26033.856975926486 26542.285436846196 22514.954992461546 27975.114876802432 25654.898409027373 21622.34588943466 23747.781743646523 25301.864305784387 1.0957268605763795 0.7805695277710847 1.028930384784917 1.049024890659074 0.8898535981522234 1.10565429245492 1.0139528889640863 0.854575205531059 0.9385783378111557 1.0 14.626956069829438 -4.442534980108885 22.918546052648317 0.9647560092771176 10.185183090142903 0.15485790880578076 0.0933244362729811 1291.668644357544 371141.65398346214 0.022423987475661 4514.042517565271 3.609649386110289e-05 4.442534980108885 9.220427080865786 ASGS(ph)ENEGDYNPGR ddPTM_PC-9_AZD4547_30min_R2 2 ASGSENEGDYNPGR 14 0 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 AS(0.019)GS(0.979)ENEGDY(0.001)NPGR;AS(0.006)GS(0.994)ENEGDYNPGR 142.4 6.8578e-05 18619600.0 11657.099999999999 12633.5 19431.300000000003 21764.4 18088.0 17814.4 16554.2 22781.7 10599.2 16142.599999999999 True False 15363.81531725733 16717.03181344239 19173.62826581414 16746.95383662801 15576.793421607028 16700.462751846615 18027.491730265258 19261.311736385946 11159.452073304334 15577.452487425038 0.9862854872874645 1.0731556926228651 1.2308577593988572 1.0750765473460475 0.999957691039755 1.0720920359300168 1.1572811244212122 1.2364866303995932 0.7163849212387485 1.0 13.927171696115447 -8.26020318385045 24.999943780551135 0.8581924639237464 1.103399991140586 0.48107443443397135 0.10207484903232401 91.01774545114158 1840783.8898526414 0.07797029379850902 0.025719430811260553 5.492838323339527e-09 8.26020318385045 0.2452075272168397 ASGS(ph)ENEGDYNPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASGSENEGDYNPGR 14 0 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 AS(0.003)GS(0.997)ENEGDYNPGR;AS(0.021)GS(0.979)ENEGDYNPGR 146.1 0.00019171 9790900.0 12249.3 17049.5 16408.9 12832.2 20236.1 14291.3 14518.5 12096.1 11184.7 10444.5 True False 14322.864555297012 18742.061683779913 16800.150407099798 12113.253436553716 16270.981471059322 13541.839069604206 13143.202575162515 11778.590191877343 11348.25507812647 12338.005171383487 1.1608736060929175 1.519051209935449 1.3616585642276855 0.9817837866245139 1.3187692212026219 1.0975711941678277 1.0652615550564515 0.9546592036771357 0.9197803794447564 1.0 13.590821535625592 -6.67017530050914 0.6133542674291638 0.9385507585559825 1.3599886916055948 0.5177407843653516 0.1317679662831039 0.6634772513831662 0.5485267464908612 0.10469129848089433 0.1280357339687414 2.1370992873518262e-07 6.67017530050914 0.4214379330496123 ASGS(ph)ENEGDYNPGR ddPTM_PC-9_Lapatinib_30min_R1 2 ASGSENEGDYNPGR 14 0 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 AS(0.003)GS(0.997)ENEGDYNPGR;AS(0.011)GS(0.989)ENEGDYNPGR 157.37 1.3362999999999999e-05 23774100.0 7829.5 13025.6 19601.2 12080.0 9780.0 13970.2 12120.6 12264.9 9277.1 12480.7 True False 7717.849894245551 12995.440023490479 17989.664998820073 12968.40349769869 9204.759628219803 13372.727112126782 12748.145361448727 12834.77202921878 8232.21530580611 14637.972365512596 0.5272485629518597 0.887789626800228 1.2289724662415775 0.8859426137634028 0.6288275041361897 0.9135641725648587 0.8708955750923301 0.8768135168404746 0.5623876791297544 1.0 13.837428106613208 -6.020146305144155 24.795332198201724 0.806068577905086 0.911228040560314 0.025321126074921763 0.19952894087590847 2333.9627384936407 2872556.2165136263 0.059847180695341284 0.07831487183511744 9.546709222611692e-07 6.020146305144155 0.10515946265522802 ASGS(ph)ENEGDYNPGRK ddPTM_PC-9_AZD4547_30min_R2 2 ASGSENEGDYNPGRK 15 1 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 AS(0.007)GS(0.992)ENEGDYNPGRK;ASGS(1)ENEGDYNPGRK 212.39 7.939299999999999e-14 11315400.0 14118.6 12590.599999999999 17894.8 31903.0 25503.0 19019.8 18739.5 24878.0 17089.6 22134.3 True False 18608.021114876716 16660.265227397616 17657.503259745386 24548.256246436533 21962.348663823726 17830.48889929338 20407.279196778207 21033.67673956769 17992.92136689011 21359.38489415657 0.871187124867413 0.7799974254855755 0.8266859437780939 1.1492960292668524 1.0282294538281442 0.8347847556308322 0.9554244795860747 0.9847510517646982 0.8423894908983336 1.0 14.382582480557707 -5.575901155054479 24.999944806142285 0.9678385533496765 0.8200271657888182 0.36690131739436094 0.08701084926863983 100.25735051407406 47270.544529543695 0.024471493826183462 0.04238588058042018 2.6552098160374406e-06 5.575901155054479 -0.14781138756085832 ASGS(ph)ENEGDYNPGRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASGSENEGDYNPGRK 15 1 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 ASGS(1)ENEGDYNPGRK;AS(0.004)GS(0.996)ENEGDYNPGRK 166.04 0.00038964 9590100.0 39711.0 34816.0 43763.0 50657.0 52406.0 39771.0 39160.0 41884.0 36123.0 33059.0 True False 46433.28797199839 38272.302389071876 44806.47589210173 47818.85252220988 42137.42049961873 37685.338747155896 35450.48130615175 40784.589379766265 36651.230536998046 39052.33500509997 1.1890015786747326 0.9800259673096057 1.1473443492239401 1.2244812638211022 1.0789987460190502 0.9649957868648429 0.9077685444806861 1.044357254807941 0.9385157259408853 1.0 15.253121191669996 -6.654151347707021 4.2039014618274475 0.9699777977443675 1.1276303288282403 0.5623057259800256 0.06854169609423681 0.17632826309982347 5.606439675901222 0.023818013437793238 0.023596481649492018 2.2174235330491086e-07 6.654151347707021 0.15765253108387278 ASGS(ph)ENEGDYNPGRK ddPTM_PC-9_Lapatinib_30min_R1 3 ASGSENEGDYNPGRK 15 1 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 AS(0.189)GS(0.811)ENEGDYNPGRK;ASGS(1)ENEGDYNPGRK;AS(0.002)GS(0.998)ENEGDYNPGRK 167.92 0.00026583 8987500.0 36582.3 28826.5 34005.6 24999.1 28037.7 23915.3 24354.8 24297.199999999997 26644.600000000002 20797.1 True False 36060.62969362781 28759.754010344866 31209.79083341202 26837.61720855292 26388.57761023908 22892.49836828719 25615.772375048382 25426.13661328951 23643.60456792334 24391.851024606167 1.4783884034569716 1.1790722229867843 1.2795171142168753 1.1002698065628351 1.0818603960650073 0.9385305914337354 1.0501774690738943 1.0424029151227583 0.969323916584764 1.0 14.574111623648719 -1.5228787452805572 0.39096874713148644 0.9857603227658415 8.151284289157202 0.8441758787945037 0.06109063195502635 25.803258042543256 0.3470079746638386 0.04461823294801136 141.37967908440223 0.029999999999984827 1.5228787452805572 7.16552396639136 ASGSLSPPILAPLS(ph)PGAEISPHDLSLESCR ddPTM_PC-9_AZD4547_30min_R2 3 ASGSLSPPILAPLSPGAEISPHDLSLESCR 30 0 Q9NRF2-2;Q9NRF2-3;Q9NRF2 Q9NRF2-2 SH2B1 SH2B adapter protein 1 1 ASGSLSPPILAPLS(0.984)PGAEIS(0.016)PHDLSLESCR;AS(0.001)GS(0.001)LS(0.014)PPILAPLS(0.984)PGAEISPHDLSLESCR;ASGSLSPPILAPLS(1)PGAEISPHDLSLESCR 127.11 2.6671e-16 65388500.0 43817.8 42105.1 94069.0 162808.0 135303.0 121174.0 79392.0 156288.0 92674.0 113384.0 True False 57750.94893314102 55714.7501648928 92821.58359640728 125275.13095852557 116518.51394978422 113596.9706244535 86457.7341973167 132137.28074095832 97572.5584422792 109414.4606714039 0.5278182479606607 0.5092082876706459 0.8483484086730662 1.1449595436452848 1.0649279193516785 1.0382262995895088 0.7901856268977885 1.2076765715438302 0.8917702271120398 1.0 16.739443897761383 -5.396352604217773 3.2675314665409787 1.0209604984221519 0.5141781394624844 0.7557959885795218 0.11235784960094167 0.11124124805246179 2.192382322363856 0.029738040951269633 0.07044657270178126 4.014647287923278e-06 5.396352604217773 -0.5067823589596675 ASGSLSPPILAPLS(ph)PGAEISPHDLSLESCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASGSLSPPILAPLSPGAEISPHDLSLESCR 30 0 Q9NRF2-2;Q9NRF2-3;Q9NRF2 Q9NRF2-2 SH2B1 SH2B adapter protein 1 1 ASGSLSPPILAPLS(1)PGAEISPHDLSLESCR;ASGSLSPPILAPLS(1)PGAEISPHDLSLESCR 110.78 1.1648e-15 34288000.0 14225.1 16719.9 20478.3 26603.4 39573.0 40230.0 42088.0 38551.0 39582.0 28017.0 True False 16633.128471468208 18379.741174030405 20966.580336385217 25112.897747386498 31818.954727157423 38120.26797913255 38101.119949267515 37539.07709816087 40160.81186821299 33096.26031755005 0.5025682150151602 0.555341932825085 0.6335030041224087 0.7587835455255291 0.9614063468761362 1.1517998593611014 1.1512213036668535 1.1342392384512072 1.2134546768390266 1.0 15.01438058975029 -6.159512622191437 1.2404925399960296 1.1486335447318003 0.5276859771609274 0.9518672808982083 0.05639363289066794 0.08376878413720425 0.26279132143496414 0.021177906742719514 0.03391638072118457 6.926077994204246e-07 6.159512622191437 -0.620947567570873 ASGSLSPPILAPLS(ph)PGAEISPHDLSLESCR ddPTM_PC-9_Lapatinib_30min_R1 2 ASGSLSPPILAPLSPGAEISPHDLSLESCR 30 0 Q9NRF2-2;Q9NRF2-3;Q9NRF2 Q9NRF2-2 SH2B1 SH2B adapter protein 1 1 ASGSLS(0.002)PPILAPLS(0.998)PGAEISPHDLSLESCR;ASGSLSPPILAPLS(1)PGAEISPHDLSLESCR 130.43 1.4325999999999998e-15 38468000.0 31325.8 26170.8 50906.0 34827.0 63335.0 78239.0 65329.0 60295.0 83036.0 55262.0 True False 30879.08834755184 26110.203120529157 46720.70518284262 37388.293759466236 59609.75982140091 74892.90035401704 68711.41596274805 63096.52581771933 73683.61127215573 64813.963068013625 0.47642648105236746 0.402848427786 0.7208432098777151 0.5768555414553528 0.9197055233121357 1.1555056473776633 1.0601329205968253 0.9735020484939013 1.1368477992131818 1.0 15.984017030297208 -6.2716155894383 1.8300835965854636 1.0679047985118917 0.5131058346410563 0.8785094817162834 0.09172862187090587 0.11519298637109128 0.7599975527094915 0.03298303594472927 0.04319268559621145 5.350377321095897e-07 6.2716155894383 -0.5547989638708354 ASHMGVS(ph)TDSGTQETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASHMGVSTDSGTQETK 16 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 ASHMGVS(0.798)T(0.2)DS(0.001)GTQETK;ASHMGVS(0.5)T(0.5)DSGTQETK 100.97 0.0018077000000000002 1619100.0 27834.4 20861.1 30290.0 37375.0 40677.0 37423.0 25528.8 35354.0 26097.6 17772.3 True False 32546.21416554085 22932.05214179307 31012.22847546468 35280.999921384886 32706.633852287756 35460.47200057366 23110.527251493542 34425.99496065936 26479.228028191486 20994.277304550607 1.5502421775902857 1.0923001448981737 1.477175328571212 1.680505568712173 1.5578832925674675 1.6890541877756104 1.1008012762832386 1.6397799486623605 1.2612593252948978 1.0 14.357708506036923 -8.539432569317109 6.48036117396938 1.0000410520056418 1.4649096581146788 0.3481351759515052 0.2036769065466753 0.17810970374229754 47.54963787797718 0.19707910985964702 0.05103013952084478 2.887802118646834e-09 8.539432569317109 0.464868606109037 ASHMGVS(ph)TDSGTQETK ddPTM_PC-9_Lapatinib_30min_R1 2 ASHMGVSTDSGTQETK 16 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 ASHMGVS(0.938)T(0.062)DSGTQETK;ASHMGVS(0.844)T(0.155)DS(0.001)GTQETK 100.27 0.0035796 0.0 16860.2 10917.4 19587.4 20919.4 11608.1 11093.9 9939.6 10188.599999999999 17644.5 13549.900000000001 True False 16619.770456217986 10892.121431063051 17976.99958155054 22457.88246107268 10925.334380402677 10619.439758144008 10454.22385316368 10661.999551312967 15657.190605177897 15891.982160893145 1.0457959421270795 0.6853847003343794 1.1311993305522445 1.4131580462213735 0.6874746189488966 0.6682262571547705 0.6578300772882406 0.6709043241660518 0.985225785346461 1.0 13.956011458631426 ASHS(ph)AVDITK ddPTM_PC-9_AZD4547_30min_R2 1 ASHSAVDITK 10 0 H0YJ30;G3V582;F5H039;Q9NQX3;Q9NQX3-2 H0YJ30 GPHN Gephyrin;Molybdopterin adenylyltransferase;Molybdopterin molybdenumtransferase 1 AS(0.125)HS(0.875)AVDITK 78.28699999999999 0.011676 21984000.0 45160.0 67403.0 92935.0 112730.0 91486.0 88128.0 82591.0 103890.0 81239.0 71586.0 True False 59519.940613646664 89189.7016124951 91702.6211773498 86741.84016113814 78784.74806330944 82617.34222846321 89941.4390000323 87836.1876547023 85533.12768729443 69079.79592908255 0.8616114134840518 1.2911112491423313 1.3274883045614652 1.2556759757974312 1.1404890099008111 1.1959696915329385 1.3019934090767487 1.2715177639620576 1.2381786387311118 1.0 16.075976200509288 -4.756316051954914 24.999965338933684 1.236262706016094 0.8616108343666752 0.5833573360457568 0.09159186108697139 108.34394453279356 528619.8553180819 0.02197708008153234 0.18012488403904475 1.7526046032641655e-05 4.756316051954914 -0.3746518716494188 ASHS(ph)AVDITK ddPTM_PC-9_Lapatinib_30min_R1 1 ASHSAVDITK 10 0 H0YJ30;G3V582;F5H039;Q9NQX3;Q9NQX3-2 H0YJ30 GPHN Gephyrin;Molybdopterin adenylyltransferase;Molybdopterin molybdenumtransferase 1 ASHS(0.997)AVDIT(0.003)K 89.189 0.023150999999999998 0.0 25107.0 18412.0 20083.0 18547.0 22760.0 14462.0 15846.0 16090.0 23685.0 13983.0 True False 24748.9695759401 18369.368145229902 18431.85326262187 19911.008250978277 21421.301547881645 13843.493972568582 16666.428344926535 16837.60013943285 21017.345885892973 16399.94291882368 1.509088763201334 1.1200873220202332 1.1238974034151048 1.2140900946749416 1.306181469893685 0.8441184241366576 1.0162491679039314 1.0266865087747854 1.2815499413579963 1.0 14.001403172998094 -6.737450073358017 24.997205188073213 1.0342966201894812 1.2376728004541293 0.37090474427595055 0.14302075642502482 283.0945376288728 294987.94724234496 0.04767542987507298 0.047652120930329965 1.8304165195245412e-07 6.737450073358017 0.2033761802646481 ASHTAPQVLFSHR ddPTM_PC-9_Lapatinib_30min_R1 1 ASHTAPQVLFSHR 13 0 H7C3F9;O15144 H7C3F9 ARPC2 Actin-related protein 2/3 complex subunit 2 0 65.043 0.017103 4052900.0 10188.0 13052.0 13931.0 13672.0 14243.0 11720.0 13226.0 14363.0 13886.0 12447.0 False True 10042.717251749616 13021.778895912494 12785.646955215107 14677.484488455008 13405.25474281539 11218.76292065439 13910.777564684988 15030.357414709399 12322.012453937505 14598.447365415028 0.6879305038658887 0.891997523432677 0.8758223826942994 1.0054140773372398 0.9182657858926551 0.768490144180168 0.9528943192712953 1.02958602640974 0.8440632175123916 1.0 13.8335273173308 -4.460961532569359 1.7349208124092828 0.9242229099696084 0.3823613742012766 0.46368394948965175 0.07575935234918077 2.3655098505438032 3.4853485793398358 0.020973664757149343 2.784388095409406 3.459700206018028e-05 4.460961532569359 -0.5418615357683318 ASIANSDGPTAGS(ph)QTPPFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASIANSDGPTAGSQTPPFK 19 0 J3KP75;F6TH74;O75167-5;O75167-2;O75167;O75167-4;H9KVA6 J3KP75 PHACTR2 Phosphatase and actin regulator;Phosphatase and actin regulator 2 1 ASIANSDGPTAGS(0.5)QT(0.5)PPFK 213.01 1.3430999999999998e-27 9545800.0 43337.0 50198.0 53367.0 58172.0 66064.0 53228.0 57151.0 49644.0 53154.0 35826.0 True False 50673.09815523391 55181.325692975384 54639.47167547458 54912.81143616859 53119.23344439215 50436.629977461285 51737.243542591415 48340.89760216593 53931.27669251158 42320.97020154005 1.197351996277957 1.3038766698918294 1.2910732295425087 1.2975319605071418 1.2551515995835831 1.1917645020251901 1.2224966321946162 1.1422445509154897 1.2743393271865264 1.0 15.369085080935848 -14.52287874461045 0.17057630888430605 0.03722776144536538 1.2994087271311872 0.7017963427526693 0.048225474546952384 70.61943758752899 0.6648172483635624 22.910352050765862 0.1708670909243829 3.0000000046274185e-15 14.52287874461045 1.2621809656858218 ASIANSDGPTAGSQT(ph)PPFK ddPTM_PC-9_AZD4547_30min_R2 2 ASIANSDGPTAGSQTPPFK 19 0 J3KP75;F6TH74;O75167-5;O75167-2;O75167;O75167-4;H9KVA6 J3KP75 PHACTR2 Phosphatase and actin regulator;Phosphatase and actin regulator 2 1 ASIANS(0.001)DGPT(0.046)AGS(0.213)QT(0.741)PPFK;ASIANS(0.015)DGPT(0.036)AGS(0.218)QT(0.731)PPFK 114.21 0.0001979 19965400.0 67586.0 65923.0 89406.0 100232.0 105183.0 110911.0 101089.0 106281.0 96402.0 100210.0 True False 89076.94212386888 87231.32055547259 88220.4180231573 77125.06096896307 90580.15604073937 103975.71763685896 110085.72516465824 89857.71354441643 101497.6129114165 96701.67840154994 0.9211519758114265 0.9020662515623352 0.9122945897259969 0.7975565909901198 0.9366968344086936 1.0752214372650684 1.1384055270223084 0.9292259972085054 1.0495951527330438 1.0 16.561253309588473 -6.600571669526715 5.016956596842799 1.0393216453776821 0.8844019050192158 0.6077226976570487 0.05920764991440257 0.14542001064044072 6.59273257201401 0.020380092002830325 0.020434773778513653 2.5085821660718964e-07 6.600571669526715 -0.15491974035846634 ASIANSDGPTAGSQT(ph)PPFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASIANSDGPTAGSQTPPFK 19 0 J3KP75;F6TH74;O75167-5;O75167-2;O75167;O75167-4;H9KVA6 J3KP75 PHACTR2 Phosphatase and actin regulator;Phosphatase and actin regulator 2 1 ASIANSDGPT(0.001)AGS(0.094)QT(0.905)PPFK;ASIANSDGPTAGS(0.047)QT(0.953)PPFK;ASIANSDGPTAGS(0.107)QT(0.893)PPFK 206.8 4.2121e-20 27129300.0 159453.0 195972.0 202344.0 227115.0 259180.0 215093.0 222773.0 200871.0 194834.0 174959.0 True False 186445.24355969552 215426.80502617208 207168.64835389337 214390.48286676445 208395.53953919717 203813.14443041425 201670.3287031499 195598.3490904173 197683.07866028548 206677.68172531755 0.9021063232530753 1.04233221133418 1.0023755183650083 1.0373180165224491 1.0083117722220376 0.9861400743854366 0.9757721637848511 0.9463931831322498 0.9564800466603538 1.0 17.657023080894255 -7.167034518150201 2.3984353536305587 0.9640146583946497 1.0029193092997821 0.10072693593190518 0.03834577422226116 0.5508989591044361 6.196218862930753 0.01694029406633024 0.01199674595073952 6.807152526294882e-08 7.167034518150201 0.0389046509051324 ASIANSDGPTAGSQT(ph)PPFK ddPTM_PC-9_Lapatinib_30min_R1 2 ASIANSDGPTAGSQTPPFK 19 0 J3KP75;F6TH74;O75167-5;O75167-2;O75167;O75167-4;H9KVA6 J3KP75 PHACTR2 Phosphatase and actin regulator;Phosphatase and actin regulator 2 1 ASIANSDGPTAGS(0.022)QT(0.978)PPFK;ASIANSDGPT(0.001)AGS(0.028)QT(0.971)PPFK 162.44 5.0989e-06 30513000.0 98862.0 104789.0 116000.0 95735.0 114199.0 100207.0 99766.0 95490.0 106585.0 80260.0 True False 97452.20975092967 104546.36750871675 106462.92777294882 102775.67126259813 107482.03934387252 95921.38020392609 104931.39532121301 99926.81400338381 94580.27491019222 94132.83406027226 1.0352626766610686 1.1106259420785825 1.1309861095309395 1.091815329779532 1.1418124230175934 1.019000236862184 1.1147162025741895 1.061551104892919 1.004753292030212 1.0 16.52241041040535 -8.144275010590118 2.784792206011525 0.9993781097394004 1.0934262105668655 0.48034051174207293 0.036776835670970696 0.23469452937636337 3.262035457536274 0.030744575848110633 0.009634133955167134 7.173399024812902e-09 8.144275010590118 0.09404810082746506 ASIANSDGPTAGSQT(ph)PPFKR ddPTM_PC-9_AZD4547_30min_R2 1 ASIANSDGPTAGSQTPPFKR 20 1 J3KP75;F6TH74;O75167-5;O75167-2;O75167;O75167-4;H9KVA6 J3KP75 PHACTR2 Phosphatase and actin regulator;Phosphatase and actin regulator 2 1 ASIANSDGPTAGS(0.013)QT(0.987)PPFKR 103.71 0.00014484 16786000.0 26313.0 30464.0 36720.0 49788.0 52749.0 48603.0 42394.0 59438.0 46127.0 47874.0 True False 34679.986655599736 40310.89224401066 36233.06880757823 38310.14581693205 45425.71186401752 45563.84672669307 46166.98387193976 50253.22284936187 48565.17904986312 46197.945831711506 0.7506824390402758 0.8725689317627665 0.7843004305768696 0.8292608064541895 0.9832842358292929 0.9862743008676551 0.9993297979116965 1.0877804617638802 1.0512410925536582 1.0 15.495541083911819 -6.367467451665937 1.6302633547550827 1.03493665412734 0.8026527205903408 0.8702280749650924 0.039779318627335344 0.1279887592969904 0.6783754920885499 0.01507901215166962 0.018680175380218142 4.290743451432047e-07 6.367467451665937 -0.23228393353699917 ASIANSDGPTAGSQT(ph)PPFKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASIANSDGPTAGSQTPPFKR 20 1 J3KP75;F6TH74;O75167-5;O75167-2;O75167;O75167-4;H9KVA6 J3KP75 PHACTR2 Phosphatase and actin regulator;Phosphatase and actin regulator 2 1 ASIANSDGPT(0.031)AGS(0.021)QT(0.948)PPFKR;ASIANSDGPTAGS(0.008)QT(0.992)PPFKR 137.9 0.0001204 18756900.0 33147.0 29967.0 41403.0 47061.0 59098.0 46854.0 41830.0 47768.0 44887.0 33052.0 True False 38758.13241690794 32941.92571499648 42390.2045417519 44424.32474382058 47518.171138542675 44396.893758247 37867.55957702576 46514.14061437962 45543.387457139004 39044.06596051196 0.9926766453090924 0.8437114553671996 1.0857015912385797 1.137799654081879 1.217039515981793 1.1370970893028596 0.9698672165784146 1.1913241992118002 1.166461185246441 1.0 15.252815679264376 -5.388933322444567 5.265225835731716 1.1229900195326827 0.9200253622983905 0.4816438189990617 0.0811136275045651 0.17272258526661688 6.596548693857894 0.021403176791016585 0.04578195959490734 4.083820807249816e-06 5.388933322444567 -0.20296465723429225 ASIANSDGPTAGSQT(ph)PPFKR ddPTM_PC-9_Lapatinib_30min_R1 3 ASIANSDGPTAGSQTPPFKR 20 1 J3KP75;F6TH74;O75167-5;O75167-2;O75167;O75167-4;H9KVA6 J3KP75 PHACTR2 Phosphatase and actin regulator;Phosphatase and actin regulator 2 1 ASIANSDGPT(0.004)AGS(0.113)QT(0.883)PPFKR;ASIANSDGPT(0.004)AGS(0.269)QT(0.727)PPFKR;ASIANSDGPT(0.002)AGS(0.014)QT(0.983)PPFKR 112.42 3.4753000000000004e-05 23278600.0 96685.0 98936.0 100948.0 82301.0 84168.0 71228.0 73311.0 91604.0 86079.0 68052.0 True False 95306.2541701425 98706.9197706098 92648.44511054858 88353.69008808785 79217.40372065475 68181.74448057766 77106.68486652202 95860.25625684317 76383.87656794528 79814.69752640968 1.1940940343550994 1.2367010441648159 1.1607942895466385 1.1069852148328034 0.9925164935248011 0.854250490118279 0.9660712532426547 1.201035137984758 0.9570151730847669 1.0 16.284366816423493 -5.935464246371449 2.1685755390928585 0.9975151234063458 1.2084103371728403 0.554396407506978 0.08199969694280031 0.2572238636735228 2.450185010802449 0.027850821183507644 0.04580082220370596 1.160207727213453e-06 5.935464246371449 0.21089521376649445 ASIDS(ph)SLENLSTASSR ddPTM_PC-9_AZD4547_30min_R2 1 ASIDSSLENLSTASSR 16 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 ASIDS(0.634)S(0.366)LENLSTASSR 220.72 1.5431e-22 7675400.0 16734.0 15986.0 30455.0 40630.0 34951.0 33549.0 22685.0 38799.0 27021.0 32389.0 True False 22055.06391117722 21153.16187673171 30051.146801056497 31263.381227242484 30098.656948174863 31451.175726474186 24703.92105333194 32803.506062323606 28449.274895535167 31255.070968444335 0.7056475390327668 0.6767913564518317 0.9614806772122405 1.0002658851360964 0.9630007552554589 1.0062743341145455 0.7903972151678507 1.0495418837935961 0.9102290928808977 1.0 14.931802657884665 -5.262995932704227 24.988112748980402 0.959037492089454 0.6912194275744685 0.7197188208959115 0.06712666622105518 62.21082255629157 998720.9132994841 0.016756660813224113 0.03813049389392297 5.457629722983631e-06 5.262995932704227 -0.26781806451498547 ASIDSS(ph)LENLSTASSR ddPTM_PC-9_AZD4547_30min_R2 3 ASIDSSLENLSTASSR 16 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 ASIDS(0.262)S(0.738)LENLSTASSR;ASIDS(0.072)S(0.928)LENLSTASSR;ASIDS(0.318)S(0.682)LENLSTASSR 177.07 8.9912e-06 26495900.0 52672.0 41429.0 71831.0 106895.0 95137.0 90396.0 72215.0 90753.0 80476.0 89569.0 True False 69420.60035434017 54820.114061748915 70878.47400645829 82252.00926128683 81928.86973415669 84743.52382993112 78641.99510100794 76729.20914647442 84729.79706498969 86433.21657268167 0.8031703910494226 0.63424822348999 0.8200374441330271 0.9516249946815427 0.9478863911684082 0.9804508867105542 0.9098584805631744 0.8877282622237348 0.9802920731723598 1.0 16.399298231004508 -5.579804787803325 3.5908772876737145 0.945543164309181 0.7182300833950749 0.7806115590029032 0.04996677230877772 0.09348449066528208 2.453742885423212 0.013285665058385843 0.025586282830577824 2.631450543895423e-06 5.579804787803325 -0.22731308091410607 ASIDSS(ph)LENLSTASSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASIDSSLENLSTASSR 16 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 ASIDS(0.046)S(0.954)LENLSTASSR;AS(0.002)IDS(0.324)S(0.674)LENLSTASSR 252.37 1.9887999999999996e-48 15165700.0 23092.2 27039.0 41031.0 46286.0 52794.0 45274.0 53846.0 47746.0 45501.0 30117.0 True False 27001.25336826022 29723.253225474342 42009.33465093401 43692.74548123668 42449.394684900035 42899.751739678024 48745.31706871933 46492.71809106868 46166.366045565104 35576.9736939592 0.758953068929663 0.835463226331733 1.1808012399342163 1.2281186662218968 1.1931704773446692 1.205829144117511 1.370136692570792 1.3068204870658497 1.2976473615405892 1.0 15.118656174516314 -5.253619659627533 2.6586566256724398 1.244895679438351 0.7603177612914611 0.7710652130881678 0.09323699501699925 0.12240324065738747 1.673646859759463 0.024984817006004512 0.08071975196552021 5.5767392704030545e-06 5.253619659627533 -0.4845779181468899 ASIDSS(ph)LENLSTASSR ddPTM_PC-9_Lapatinib_30min_R1 4 ASIDSSLENLSTASSR 16 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 ASIDS(0.052)S(0.948)LENLSTASSR;ASIDS(0.322)S(0.678)LENLSTASSR;ASIDS(0.323)S(0.676)LENLSTAS(0.001)SR;ASIDS(0.235)S(0.765)LENLSTASSR 208.07 3.9969e-17 28633800.0 130757.0 94393.0 110887.0 102747.0 116446.0 106098.0 96959.0 76221.0 121429.0 72215.0 True False 128892.38120210309 94174.43880798844 101770.29889619835 110303.35713394427 109596.87522164457 101560.43586651789 101979.06259596931 79762.50591844061 107752.38731594245 84697.26652956122 1.5218009563167754 1.1118946651615902 1.201577135440118 1.3023248760388975 1.2939836161464884 1.1990993337556064 1.2040419576041024 0.9417364832028166 1.2722061966230573 1.0 16.370027789155543 -1.522878745394099 0.08349853178273227 0.8308795766970472 2.213317772106195 0.3696414918407056 0.12359101747866334 206.52464816668143 1.256103950202336 2.986508934076733 32.82837524229076 0.029999999992141632 1.522878745394099 1.3824381954091478 ASIGQS(ph)PGLPSTTFK ddPTM_PC-9_AZD4547_30min_R2 2 ASIGQSPGLPSTTFK 15 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 AS(0.002)IGQS(0.995)PGLPS(0.001)T(0.002)TFK;AS(0.052)IGQS(0.909)PGLPS(0.028)T(0.009)T(0.002)FK 156.17 2.1455e-05 90808000.0 111394.0 120289.0 149416.0 182367.0 142827.0 147614.0 122354.0 156044.0 116930.0 136770.0 True False 146814.97486086257 159170.06687039803 147434.64621332008 140325.10569206323 122997.93642347772 138383.6732447392 133243.26896889473 131930.9853343959 123110.68108267388 131981.72392954776 1.1123886738987652 1.2060008168658525 1.117083803906222 1.0632161901974335 0.9319315793233189 1.0485063319722119 1.0095584828094863 0.9996155634762056 0.9327858238038377 1.0 17.009978641735046 -5.851982634740367 2.4876840459256466 0.991302919960376 1.1576587852540814 0.7533801824531301 0.04053870504189135 0.13136175867949348 1.652516141280582 0.01188082666119702 0.02021310808833699 1.4061037460472547e-06 5.851982634740367 0.16635586529370538 ASIGQS(ph)PGLPSTTFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASIGQSPGLPSTTFK 15 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 ASIGQS(0.61)PGLPS(0.091)T(0.159)T(0.139)FK;ASIGQS(0.44)PGLPS(0.424)T(0.118)T(0.017)FK 79.32600000000001 0.010986 29775200.0 65800.0 56362.0 68600.0 69299.0 80632.0 83074.0 98045.0 87808.0 74417.0 74405.0 True False 76938.64039076063 61957.246876518504 70235.68416694882 65416.401700389266 64832.73842165516 78717.45319658103 88757.46781567048 85503.13304026653 75505.20784186758 87894.03751034402 0.8753567656020572 0.7049084173568306 0.7990949802332492 0.7442643841761233 0.73762385092419 0.8955949166326213 1.0098235367242612 0.9727978764225491 0.8590481218135141 1.0 16.42347767977568 -6.9124292026691405 4.286495835032157 0.9578504302678734 0.7690329686558067 0.7087750681121325 0.05721525093529844 0.1155983603190065 3.9363272154917692 0.020277715439064394 0.017684540657410305 1.2234065387103784e-07 6.9124292026691405 -0.1888174616120667 ASIGQS(ph)PGLPSTTFK ddPTM_PC-9_Lapatinib_30min_R1 2 ASIGQSPGLPSTTFK 15 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 ASIGQS(1)PGLPSTTFK;AS(0.001)IGQS(0.985)PGLPS(0.012)T(0.002)T(0.001)FK 185.71 4.127399999999999e-07 59669000.0 89493.0 78904.0 98797.0 82352.0 108422.0 118816.0 120870.0 119717.0 134103.0 101851.0 True False 88216.81340899372 78721.30263584745 90674.29202744876 88408.44079821875 102044.83112585357 113734.51665362385 127128.05717854785 125279.4888683952 118998.90797280573 119455.80964207323 0.738489100474215 0.658999364465579 0.7590613826078207 0.7400932701650756 0.8542475366548653 0.9521053600859418 1.0642266588746336 1.0487517454678137 0.9961751406596587 1.0 16.86611749430883 -6.598100584500223 1.4647847488591619 1.033065862414518 0.7121742253445014 0.9485935809869149 0.032002460216049924 0.07814908676989583 0.3467199923503175 0.01346920817961946 0.0140017239701212 2.5228963909793067e-07 6.598100584500223 -0.32089163707001656 ASIGQSPGLPSTT(ph)FK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASIGQSPGLPSTTFK 15 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 ASIGQS(0.243)PGLPS(0.272)T(0.169)T(0.316)FK 115.68 0.00038184 31920000.0 33940.0 29582.0 35275.0 39996.0 43396.0 43940.0 55932.0 46234.0 49127.0 50059.0 True False 39685.37165444402 32518.705459372824 36116.08978118249 37755.153788781536 34892.865320792574 41635.70904805085 50633.716047387155 45020.40648897224 49845.389435847064 59134.30043317402 0.6711057941624137 0.5499127447380777 0.6107468849148938 0.6384645377084921 0.5900613529743876 0.7040872850961037 0.8562495146891417 0.7613247499198628 0.8429183920451703 1.0 15.851707577809004 -7.8048436005229975 0.48955620228327157 0.9921740225919495 0.581850776375743 0.850499070389072 0.051984495056040886 0.33065754865236413 0.18974977262885356 0.05586718779821217 0.03818995082179234 1.5673153949742912e-08 7.8048436005229975 -0.4103232462162065 ASIHEAWTDGK ddPTM_PC-9_AZD4547_30min_R2 1 ASIHEAWTDGK 11 0 O43707;O43707-2;P12814-4;P12814-3;P12814;P12814-2;H9KV75 O43707;P12814-4 ACTN4;ACTN1 Alpha-actinin-4;Alpha-actinin-1 0 110.08 0.0016629000000000001 27558000.0 39076.0 33038.0 105840.0 196280.0 147650.0 109570.0 73170.0 133080.0 86117.0 103100.0 False True 51501.355168708105 43716.88740669727 104436.49244537253 151030.6784957704 127151.34612451766 102718.5705788483 79681.98825092762 112515.54387417262 90668.96880866005 99490.50038119788 0.5176509814643674 0.4394076543910826 1.0497132092533867 1.5180411990802771 1.2780249937163572 1.032446014295657 0.8009004673373443 1.1309174588837054 0.911332925869926 1.0 16.6022711594046 -5.285084063065868 6.293998079285354 1.1060961342825975 0.476351249770682 0.6286705262691367 0.1878608329501908 0.10549687684228601 16.53586477518617 0.05420867956371717 0.12075988116810818 5.186996284859987e-06 5.285084063065868 -0.6297448845119155 ASIHEAWTDGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASIHEAWTDGK 11 0 O43707;O43707-2;P12814-4;P12814-3;P12814;P12814-2;H9KV75 O43707;P12814-4 ACTN4;ACTN1 Alpha-actinin-4;Alpha-actinin-1 0 ;; 123.67 0.00046172 9581200.0 83185.0 95736.0 165913.0 183313.0 208875.0 197734.0 175677.0 153610.0 171476.0 117730.0 False True 97266.57752135916 105240.03738281768 169868.99514855634 173042.56691876476 167947.44317173384 187364.48094918695 159035.60276866218 149577.90026324816 173983.51209928005 139073.51704983303 0.6993896435833031 0.7567223409264031 1.2214330862696787 1.2442524686907852 1.2076162790328706 1.3472333548741005 1.1435362112232792 1.0755311538547716 1.2510182800434826 1.0 17.08548819655713 -5.241208110195527 6.262921417230826 1.196473276446304 0.7224832414034223 0.7956228549188599 0.09282592552535471 0.06732985537043489 10.73189697815301 0.02367244553229864 0.06028784114931787 5.738414164216206e-06 5.241208110195527 -0.4739900350428816 ASIHEAWTDGK ddPTM_PC-9_Lapatinib_30min_R1 2 ASIHEAWTDGK 11 0 O43707;O43707-2;P12814-4;P12814-3;P12814;P12814-2;H9KV75 O43707;P12814-4 ACTN4;ACTN1 Alpha-actinin-4;Alpha-actinin-1 0 ; 109.39 0.0017347 8014400.0 57862.0 68926.0 95195.0 84100.0 101221.0 116070.0 87661.0 85219.0 124346.0 63515.0 False True 57036.87726940875 68766.40608180086 87368.43456332658 90284.99454937587 95267.37978814285 111105.95667238532 92199.65765143288 89178.58584725465 110340.84405857087 74493.48312158223 0.7656626442922232 0.9231197575976666 1.1728332587258792 1.2119851397204775 1.2788686445585467 1.4914855906394815 1.2376875639034364 1.197132716988204 1.4812147242260303 1.0 16.184826600031457 -5.125349345180012 1.2606221766575025 1.2952365702278346 0.6776011791200233 0.6264022661669721 0.1328102618236567 0.5032020015331794 1.0466626539222967 0.03975487247856813 0.3445780148158525 7.492912392234862e-06 5.125349345180012 -0.6176353911078113 ASIPFSVVGSNQLIEAK ddPTM_PC-9_Lapatinib_30min_R1 1 ASIPFSVVGSNQLIEAK 17 0 Q15019-2;Q15019-3;Q15019;B5MCX3;H7C2Y0 Q15019-2 SEPT2 Septin-2 0 91.307 0.010313 2892300.0 8948.6 7830.7 8185.2 5640.8 7292.1 5794.4 9065.7 5877.7 6160.8 5416.3 False True 8820.991323027738 7812.568495266772 7512.244451785712 6055.64324915718 6863.1930148202 5546.587019406127 9535.077587189224 6150.799399598787 5466.905827899914 6352.500238233904 1.3885857524155107 1.229841511574471 1.1825650011898676 0.953269267541302 1.0803924057353953 0.8731344842811318 1.5009960219757703 0.9682485901501999 0.8605912039162394 1.0 12.633108809045222 -5.122193551475819 1.5383812496604543 1.0487072808293667 1.4040825936050687 0.2983248238114643 0.17282443613776732 0.8323268136986084 2.87342213153436 0.05134833739072095 0.369063124108679 7.547557816388282e-06 5.122193551475819 0.355375312775702 ASIQECILPDS(ph)PLYHNK ddPTM_PC-9_AZD4547_30min_R2 2 ASIQECILPDSPLYHNK 17 0 Q9NXE4-3;Q9NXE4-6;Q9NXE4-2;Q9NXE4;Q9NXE4-4 Q9NXE4-3 SMPD4 Sphingomyelin phosphodiesterase 4 1 ASIQECILPDS(0.999)PLY(0.001)HNK;ASIQECILPDS(1)PLYHNK 121.35 4.1355e-05 8766400.0 46882.0 47330.0 69775.0 61007.0 59176.0 44903.0 59194.0 69103.0 52499.0 44828.0 True False 61789.50079382164 62628.49691140443 68849.73790982491 46942.778698754206 50960.433852112845 42095.20831160004 64462.151326027306 58424.719178967236 55273.98996116728 43258.58536458125 1.4283754374550792 1.4477703416229288 1.5915855160209855 1.0851667548331216 1.178042079338027 0.9731064471208125 1.4901585611906498 1.35059245896662 1.2777576866030358 1.0 15.400698866835626 -5.759026597464393 24.99999902904903 1.2106821431592707 1.4850964356879304 0.4349736122746516 0.15355140108624557 67.2318350411648 696603.2157367973 0.04434448272264586 0.07238507336188836 1.74170020331029e-06 5.759026597464393 0.2744142925286597 ASIQECILPDS(ph)PLYHNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASIQECILPDSPLYHNK 17 0 Q9NXE4-3;Q9NXE4-6;Q9NXE4-2;Q9NXE4;Q9NXE4-4 Q9NXE4-3 SMPD4 Sphingomyelin phosphodiesterase 4 1 ASIQECILPDS(0.993)PLY(0.007)HNK 94.463 0.00098942 2599800.0 24372.0 17244.0 22830.0 18911.0 27898.0 16049.0 19184.0 15974.0 17893.0 13848.0 True False 28497.69823105801 18955.870358374174 23374.353783257135 17851.47798028923 22431.58716746869 15207.362187350192 17366.752639867602 15554.699425852039 18154.651274769716 16358.53277929231 1.7420693295386638 1.1587757052618888 1.428878377946334 1.0912640039995998 1.3712468880989157 0.9296287382570554 1.0616326582694238 0.9508615250349459 1.1097970410739433 1.0 13.997755736205436 -1.5228787452822072 0.36855036166127847 1.005094415573652 9.227621922710211 0.6292439794911837 0.14778741372278342 42.08895780081456 0.5824109603946483 0.11160913207110969 244.68060750258368 0.02999999999987085 1.5228787452822072 8.22252750713656 ASIQECILPDS(ph)PLYHNK ddPTM_PC-9_Lapatinib_30min_R1 2 ASIQECILPDSPLYHNK 17 0 Q9NXE4-3;Q9NXE4-6;Q9NXE4-2;Q9NXE4;Q9NXE4-4 Q9NXE4-3 SMPD4 Sphingomyelin phosphodiesterase 4 1 ASIQECILPDS(1)PLYHNK;ASIQECILPDS(0.999)PLY(0.001)HNK 112.36 0.00015026 6962900.0 36597.0 47751.0 31325.0 15198.2 25381.0 29769.0 23023.4 16343.099999999999 34742.0 10936.7 True False 36075.12006893216 47640.435493312674 28749.579417996803 16315.926327708958 23888.139480965918 28495.84926492836 24215.43899763861 17102.46008941984 30828.990110521183 12827.094022763271 2.8124156574289065 3.714047422492484 2.2413166510650897 1.2719892984922634 1.8623188883291453 2.221535853277363 1.887835152269509 1.3333074552248079 2.403427468124215 1.0 13.646906744535823 -5.4461619560064625 4.845168800131273 1.7582587328678707 3.240789670530205 0.6438182451042296 0.455224535033399 0.12524136107988645 5.29671978974845 0.11512730414575682 0.24449672063319736 3.579629215761786e-06 5.4461619560064625 1.4825309376623343 ASITALEAK ddPTM_PC-9_Lapatinib_30min_R1 1 ASITALEAK 9 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 134.26 0.0051847 7890700.0 56399.0 63581.0 49724.0 59753.0 81762.0 65434.0 70149.0 59088.0 68231.0 67097.0 False True 55594.73991769013 63433.782100904995 45635.88466019065 64147.434950164716 76952.91991027673 62635.54035410402 73780.9719783069 61833.444191349205 60546.106275717226 78694.62704886717 0.7064616988802469 0.8060751347295207 0.5799110609146421 0.8151437697306951 0.9778675215334728 0.7959315991828654 0.9375604757932327 0.7857390842319179 0.7693804335348051 1.0 16.26397751725718 -5.987508518064289 24.571292970011836 0.868712723439377 0.7065394057728571 0.43971012651282093 0.09048859469895887 183.34348663296902 360640.50700626423 0.024724276285813463 0.036644365437965766 1.0291803410980144e-06 5.987508518064289 -0.16217331766651988 ASKPLPPAPAPDEYLVS(ph)PITGEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASKPLPPAPAPDEYLVSPITGEK 23 1 Q15459;Q15459-2;H7C1L2 Q15459 SF3A1 Splicing factor 3A subunit 1 1 ASKPLPPAPAPDEY(0.372)LVS(0.598)PIT(0.031)GEK;ASKPLPPAPAPDEY(0.375)LVS(0.54)PIT(0.084)GEK 65.899 0.0013805 4944900.0 18493.1 28821.0 33664.0 26739.0 36105.0 26257.0 29392.0 25409.0 19249.4 22237.1 True False 21623.616574625754 31682.158408646625 34466.677431430944 25240.900519007646 29030.484431911143 24880.03669719322 26607.77698034763 24742.04067306086 19530.886058713033 26268.510201213252 0.8231763586511668 1.2060888937349532 1.3120910614047328 0.9608805495882997 1.1051439236386662 0.9471430433859966 1.0129153414691445 0.941889756348577 0.7435094685274907 1.0 14.681046760977633 -7.121359488573381 1.0126557306698618 0.8873023368845334 1.1031051573471327 0.22563587209578306 0.14067880144794448 0.759362502461031 1.5640747958757402 0.09647633076272649 0.062011018845252466 7.562066835087833e-08 7.121359488573381 0.21580282046259924 ASKPLPPAPAPDEYLVS(ph)PITGEK ddPTM_PC-9_Lapatinib_30min_R1 1 ASKPLPPAPAPDEYLVSPITGEK 23 1 Q15459;Q15459-2;H7C1L2 Q15459 SF3A1 Splicing factor 3A subunit 1 1 ASKPLPPAPAPDEY(0.282)LVS(0.658)PIT(0.06)GEK 57.919 0.0034459000000000004 3930200.0 20532.0 25477.0 25015.0 17805.0 23009.0 14522.0 21459.0 23638.0 25881.0 24107.0 True False 20239.20991489234 25418.009571802202 22958.36326069242 19114.43909573883 21655.655857434496 13900.927912435414 22570.0420203066 24736.307774761575 22966.00924098782 28273.862829441627 0.715827548467032 0.8989931699510963 0.8119995275914628 0.6760462555486026 0.7659249105107924 0.4916529444982789 0.7982652443515561 0.8748824992177444 0.8122699533320672 1.0 14.787181379951392 -8.463944229761424 1.1151461099415503 0.9891314957621181 0.7396737663718608 0.3516248787116306 0.10560858336222484 0.6084249229348049 1.6561754384499277 0.1063460678177585 0.034282004517066735 3.4360206897396758e-09 8.463944229761424 -0.24945772939025734 ASLAS(ph)LDSNPSTNEK ddPTM_PC-9_AZD4547_30min_R2 2 ASLASLDSNPSTNEK 15 0 Q96BY6;A0A2R8YD85;Q96BY6-3;H7C0I3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 AS(0.003)LAS(0.997)LDSNPSTNEK;ASLAS(1)LDSNPSTNEK 171.15 0.0001325 14902900.0 129866.0 133372.0 155302.0 208960.0 194987.0 156265.0 131483.0 189518.0 148933.0 187845.0 True False 171160.68661939434 176481.8907683888 153242.59400747585 160787.50039981742 167916.4207706148 146493.72484716374 143184.73228367823 160232.34779039238 156805.29432725426 181268.60372556842 0.9442379049740077 0.9735932596224636 0.8453896088893444 0.8870124064244552 0.9263403442155478 0.808158290163408 0.7899036531469771 0.8839498098246298 0.865043869177972 1.0 17.4677695419798 -5.258263154159213 24.95513736471946 0.8683128011216176 0.9589155893265053 0.24920579549404076 0.0566007898632041 329.0286134957693 2585095.2536494513 0.014386697444157473 0.03484948749251604 5.5174301765271155e-06 5.258263154159213 0.09060278820488776 ASLAS(ph)LDSNPSTNEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASLASLDSNPSTNEK 15 0 Q96BY6;A0A2R8YD85;Q96BY6-3;H7C0I3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 ASLAS(0.879)LDS(0.121)NPSTNEK;ASLAS(1)LDSNPSTNEK 219.53 4.7799e-18 15889300.0 66326.0 72069.0 76850.0 69772.0 89505.0 57978.5 70563.0 70966.0 56099.0 51773.7 True False 77553.68180178692 79223.53403257176 78682.39545524794 65862.90104387616 71967.13776701853 54938.00539468397 63878.76180812022 69103.21769469223 56919.34174611897 61159.861969616264 1.268048672842247 1.2953517467375806 1.2865038102004993 1.0768974769203425 1.176705366058073 0.8982689565580892 1.044455624178071 1.1298785750860942 0.9306649804801072 1.0 15.900297530264275 -5.976224374013414 1.3202045040758013 1.0187123538748744 1.2977457797591028 0.6842069139993983 0.07742164498221162 0.25678274386278477 0.9085489852819152 0.027512117546329286 0.05221930308248371 1.056271655759542e-06 5.976224374013414 0.2790334258842284 ASLAS(ph)LDSNPSTNEK ddPTM_PC-9_Lapatinib_30min_R1 2 ASLASLDSNPSTNEK 15 0 Q96BY6;A0A2R8YD85;Q96BY6-3;H7C0I3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 ASLAS(0.979)LDS(0.005)NPS(0.012)T(0.004)NEK;ASLAS(0.96)LDS(0.001)NPS(0.03)T(0.009)NEK 141.06 7.7056e-05 23571000.0 88583.0 86846.0 79642.0 63367.0 85848.0 77135.0 73851.0 66830.0 84473.0 52433.0 True False 87319.79017586718 86644.91342280217 73094.14218701051 68027.22056611534 80798.58942366186 73836.11586046731 77674.64342428173 69935.1657749098 74958.761199875 61495.97418741911 1.4199269355380197 1.4089526114138387 1.1886004434086055 1.1062060803979004 1.3138842093535237 1.2006658457908088 1.2630850141109313 1.1372316106704945 1.2189214365712109 1.0 15.908204347563085 -1.5228787452803376 0.09298964120455566 0.9065978984365269 2.210738251231814 0.5633077640586036 0.08242466317931776 125.29343743306512 0.8374348480210628 1.474321606486515 20.828403661426833 0.029999999999999995 1.5228787452803376 1.304140352795287 ASLASLDS(ph)NPSTNEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASLASLDSNPSTNEK 15 0 Q96BY6;A0A2R8YD85;Q96BY6-3;H7C0I3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 ASLAS(0.017)LDS(0.92)NPS(0.051)T(0.012)NEK 103.43 0.0012865 7539200.0 16544.0 15135.0 14675.0 18450.0 17306.0 14560.0 15989.0 14330.0 13419.0 11411.0 True False 19344.572441105516 16637.50277626961 15024.907655247425 17416.30631570706 13915.013532160474 13796.447968584884 14474.406169664471 13953.852683890049 13615.22748874615 13479.723970573696 1.4350866889659473 1.234261384920742 1.114630217061334 1.2920373112778083 1.0322921717489926 1.0234963266831427 1.073790991659931 1.0351734734592029 1.0100523956179117 1.0 13.718503333757518 -1.52287874530006 0.3476723773267883 1.0052437486041248 5.720285715899878 0.7913733128493925 0.06370529529523117 27.863241184346784 0.39289470108355223 0.05530721610420489 85.92652941196542 0.029999999998637616 1.52287874530006 4.715041967295753 ASLASLDSNPS(ph)TNEK ddPTM_PC-9_Lapatinib_30min_R1 1 ASLASLDSNPSTNEK 15 0 Q96BY6;A0A2R8YD85;Q96BY6-3;H7C0I3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 ASLASLDS(0.4)NPS(0.508)T(0.092)NEK 158.45 0.00024777 5858900.0 33736.0 27896.0 27554.0 24825.0 24952.0 21806.0 21535.0 20736.0 29967.0 13940.0 True False 33254.91845357528 27831.408525925122 25288.616481515834 26650.713313772336 23484.372417519462 20873.408212268747 22649.976928435728 21699.47026048972 26591.800893500327 16349.510426117566 2.0340008713931965 1.7022777930687008 1.5467506868657346 1.6300618562375475 1.4363960635790227 1.2766992814001616 1.3853611721763526 1.3272244669678823 1.6264585422093856 1.0 13.996959815493778 -1.5228787452803376 0.3207618514367152 1.2796827659910508 8.193551079632968 0.6916046387276902 0.14775921645309834 33.37053819142646 0.47620496105982 0.1360546829638281 135.45344344135412 0.029999999999999995 1.5228787452803376 6.913868313641917 ASLASLDSNPST(ph)NEK ddPTM_PC-9_AZD4547_30min_R2 1 ASLASLDSNPSTNEK 15 0 Q96BY6;A0A2R8YD85;Q96BY6-3;H7C0I3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 AS(0.001)LAS(0.047)LDS(0.001)NPS(0.072)T(0.879)NEK 134.84 3.9885e-05 14918000.0 43182.0 38039.0 46605.0 56012.0 44796.0 39402.0 39727.0 56009.0 38677.0 43930.0 True False 56912.977758602545 50334.36285681204 45986.98724883398 43099.298776773474 38576.84863524482 36938.18671121451 43262.626038603354 47354.09600878076 40721.38725933956 42392.024071251326 1.3425397584919467 1.187354554531566 1.0848028197837485 1.0166841456858342 0.9100025177001678 0.8713475593694192 1.0205369285007186 1.1170520173603724 0.9605907750688241 1.0 15.371505231241889 -5.0410836898690885 1.2840481310691072 0.9828167125889526 1.404509266904353 0.7700290194975115 0.06328083528535546 0.4738583156455287 0.9453326470928772 0.021859362358928734 0.23342802808721877 9.097379464674168e-06 5.0410836898690885 0.4216925543154004 ASLASLDSNPST(ph)NEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASLASLDSNPSTNEK 15 0 Q96BY6;A0A2R8YD85;Q96BY6-3;H7C0I3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 ASLAS(0.187)LDS(0.03)NPS(0.187)T(0.596)NEK 94.53200000000001 0.0073704999999999994 6313900.0 21478.0 24973.0 23325.0 19927.0 26866.0 23416.0 22082.0 19621.0 18486.0 13575.0 True False 25113.80119016347 27452.154399192677 23881.15646055509 18810.554794205655 21601.800159194696 22188.023738487907 19990.233100164547 19105.96954016795 18756.322777923928 16036.040040359136 1.566084964053322 1.711903582811076 1.4892178119069013 1.173017449873141 1.3470782128772305 1.3836348426822085 1.246581640470689 1.1914393760605788 1.169635566556235 1.0 13.969030304417885 -1.522878745765383 0.16433724945717604 0.9730619024118833 3.7434520513239224 0.7714189144647176 0.09745267582588787 30.596089465024228 0.32316406126190783 0.29443790843057943 20.650618451836255 0.029999999966494252 1.522878745765383 2.770390148912039 ASLENSLR ddPTM_PC-9_AZD4547_30min_R2 3 ASLENSLR 8 0 P05783;F8VZY9;CON__H-INV:HIT000015463 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ;; 117.81 0.016266 103079500.0 170401.0 174015.0 209640.0 291403.0 238182.0 220779.0 184561.0 239399.0 196714.0 207011.0 False True 224584.97343901754 230261.9457012053 206860.03662365733 224224.54048147018 205114.5406205887 206973.65422859846 200986.57145796763 202405.38539174234 207111.90044040952 199763.60789924415 1.1242536906536684 1.1526721414510281 1.0355241317427168 1.1224493932576725 1.026786323983713 1.036092892019606 1.006122053819434 1.0132245183208277 1.0367849410532857 1.0 17.60793425734012 -5.615445252072961 0.5633935388275028 1.009282776975801 1.167900127884519 0.6840793069779929 0.02969276435119325 0.9866234784815305 0.44985840606427324 0.01836082455680843 0.09206900899247926 2.4241235345747375e-06 5.615445252072961 0.15861735090871787 ASLENSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASLENSLR 8 0 P05783;F8VZY9;CON__H-INV:HIT000015463 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ;; 117.81 0.016266 76376200.0 174842.0 187761.0 206941.0 181901.0 231061.0 207190.0 200934.0 178855.0 184153.0 142769.0 False True 204439.2973130903 206400.6712107798 211875.25826811246 171709.67670099885 185786.25573526733 196324.59166285058 181900.0768838177 174160.24576253683 186845.88924175224 168651.88954121785 1.2121968978184863 1.2238266157126945 1.2562874856870845 1.0181307613457464 1.1015960523220933 1.1640817793201754 1.0785534474510707 1.0326610999515233 1.1078790148751214 1.0 17.363688956543065 -1.522878745280387 0.18397312335932337 1.0031976530640008 2.0799182750855203 0.5556509936391321 0.057499106421869776 43.20409184038278 0.4941597304945028 0.12997298338100832 13.082996456632698 0.029999999999996592 1.522878745280387 1.0767206220215195 ASLENSLR ddPTM_PC-9_Lapatinib_30min_R1 5 ASLENSLR 8 0 P05783;F8VZY9;CON__H-INV:HIT000015463 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ;;;; 141.52 0.01027 185404400.0 398925.0 412332.0 428611.0 474869.0 443424.0 466177.0 434836.0 375546.0 430318.0 388149.0 False True 393236.256346115 411377.2705876026 393372.2580663066 509792.45037654485 417342.6721251264 446239.6964216638 457349.68041111104 392995.2381580757 381851.05539057223 455240.03747396823 0.8637998066428884 0.9036491449000159 0.8640985539168456 1.119832194912549 0.9167530045047743 0.9802294606989196 1.0046341331242497 0.8632703756434169 0.8387905806997642 1.0 18.796267919877984 -1.6237486955652738 9.416086458305312 0.936602476055461 0.8648095524148215 0.0 0.08432421410569343 0.0 0.0 0.019620233193299044 0.0 0.02378216042890994 1.6237486955652738 -0.0717929236406395 ASLGQAS(ph)IQNGK ddPTM_PC-9_AZD4547_30min_R2 1 ASLGQASIQNGK 12 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 ASLGQAS(1)IQNGK 98.59200000000001 0.010626 0.0 8461.1 6219.4 7641.5 7628.8 10778.0 11925.0 8709.4 13421.0 9623.0 12238.0 True False 11151.553798187026 8229.699423004202 7540.1687171325975 5870.098023785069 9281.660741822227 11179.327864860494 9484.519727656565 11347.092833898947 10131.652134256137 11809.551344957288 0.9442825957100199 0.6968680843678542 0.6384805397668448 0.49706359304594727 0.7859452464115432 0.9466344265173205 0.8031227817732874 0.9608402980308128 0.8579201561778536 1.0 13.527666536096522 -6.537826909392832 6.7670018660277895 0.9011541967871165 0.68429454157096 0.447213354934792 0.11482762314840775 0.1477593439670047 30.366027578594267 0.03862372587933779 0.039597640279075155 2.8984985710902884e-07 6.537826909392832 -0.21685965521615647 ASLGS(ph)LEGEAEAEAS(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 3 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 AS(0.003)LGS(0.997)LEGEAEAEAS(0.569)S(0.431)PK;AS(0.01)LGS(0.99)LEGEAEAEAS(0.543)S(0.457)PK;AS(0.004)LGS(0.996)LEGEAEAEAS(0.653)S(0.347)PK 103.85 0.007427899999999999 3894100.0 47694.6 58117.4 50977.8 48709.5 52464.6 63837.5 56488.8 57769.0 52730.8 52462.4 True False 62860.49069069161 76902.71300230005 50301.801063697196 37480.277329273136 45180.795894916155 59845.731033377924 61516.19376669418 48842.12844955727 55518.04243593824 50625.70734431177 1.2416713560794232 1.5190447114007726 0.9936019406422977 0.7403408129068713 0.8924476963380661 1.1821213800798795 1.2151177137795794 0.9647693042069683 1.0966373676194405 1.0 15.62758253996497 -5.27365505618304 24.54651619808066 1.0089251792351936 1.3803580285725126 0.5141686227823397 0.14375065163747974 438.76522475093077 881667.9494116686 0.04105299677599745 0.08651592534844729 5.325310607836683e-06 5.27365505618304 0.3714328493373189 ASLGS(ph)LEGEAEAEAS(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 AS(0.001)LGS(0.999)LEGEAEAEAS(0.605)S(0.395)PK;AS(0.061)LGS(0.939)LEGEAEAEAS(0.568)S(0.432)PK;AS(0.001)LGS(0.999)LEGEAEAEAS(0.884)S(0.116)PK 200.94 5.6326e-14 7804500.0 50294.5 64603.0 49822.5 63772.6 72651.0 54498.1 69303.3 58464.200000000004 50434.2 58515.2 True False 58808.3654883451 71016.35889364687 51010.45735288344 60199.62797555879 58415.55807956724 51640.12369757803 62738.38971155841 56929.57669794028 51171.70476286765 69123.54255393162 0.8507718689686888 1.0273830922111442 0.7379606928143768 0.8708990562598813 0.8450891826614675 0.7470699820873233 0.907626944359928 0.8235917112251973 0.7402934350904025 1.0 16.076889536489823 -5.2605778729575645 24.9999628726415 0.8289953545411819 0.9390774730553093 0.18676127131274256 0.08713927183335099 108.54086402616791 3149606.7947270535 0.02087161466042882 0.04907616190108228 5.488101401254493e-06 5.2605778729575645 0.11008211851412741 ASLGS(ph)LEGEAEAEAS(ph)SPKGK ddPTM_PC-9_AZD4547_30min_R2 1 ASLGSLEGEAEAEASSPKGK 20 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 AS(0.053)LGS(0.947)LEGEAEAEAS(0.539)S(0.461)PKGK 70.316 0.013669 10093000.0 62700.0 39676.0 60716.0 157950.0 121230.0 79011.0 68791.0 74808.0 52481.0 96101.0 True False 82637.2957589825 52500.49109353231 59910.866168870365 121537.06780317366 104399.3070821218 74070.42967970598 74913.2657341747 63248.142516825304 55255.03851791502 92736.53324086784 0.891097530509856 0.5661252287399072 0.6460330581181182 1.3105629847894054 1.1257624523332335 0.7987189847535088 0.8078074855310782 0.6820196993190234 0.5958281659548258 1.0 16.50085017516752 -10.799379448668407 5.292435193241588 1.0000252468086273 0.8296734313481546 0.05156820100025761 0.22445475329613623 7.350511719795321e-05 1.0048456235995644e-05 0.23891097784317722 0.05793584133902067 1.5871594210459907e-11 10.799379448668407 -0.17035181546047262 ASLGS(ph)LEGEAEAEASS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 AS(0.003)LGS(0.997)LEGEAEAEAS(0.286)S(0.714)PK;AS(0.003)LGS(0.997)LEGEAEAEAS(0.248)S(0.752)PK;AS(0.031)LGS(0.969)LEGEAEAEAS(0.073)S(0.927)PK;AS(0.004)LGS(0.996)LEGEAEAEAS(0.264)S(0.736)PK 159.18 2.0379e-17 9614700.0 104031.5 133575.0 101098.9 101962.0 112041.0 135525.0 135923.0 129307.0 122042.0 121269.0 True False 137111.35301037607 176750.5065485075 99758.26252915217 78456.23619719651 96486.0411184363 127050.60032580433 148019.8836822589 109325.57432925803 128492.89096631903 117023.40922141093 1.1716574822303998 1.51038589393761 0.8524641624515253 0.6704319821067215 0.8245020527122273 1.0856853442495573 1.26487413644053 0.9342197006276888 1.0980101487490215 1.0 16.836437628087573 -5.266873560988191 24.995907691172466 0.9632241315973483 1.3410216940711766 0.42738110920974237 0.1734813603378204 408.29188956460774 1878050.8629002483 0.049675490424119055 0.10837645836691612 5.409117792313489e-06 5.266873560988191 0.37779756247382823 ASLGS(ph)LEGEAEAEASS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 ASLGS(1)LEGEAEAEAS(0.059)S(0.941)PK;AS(0.001)LGS(0.999)LEGEAEAEAS(0.287)S(0.713)PK 241.98 3.2896e-43 5407400.0 39404.0 48367.0 40410.0 51772.0 58323.0 44483.0 58999.0 43165.0 38289.0 43294.0 True False 46074.31893552479 53168.556113632825 41373.527655778424 48871.38268708864 46895.02682515864 42150.23317215394 53410.18760423004 42031.964487097954 38848.90418932864 51142.85948488459 0.9008944630704934 1.0396085914857174 0.8089795539884993 0.9555856512390104 0.9169418233061175 0.8241665326635003 1.0443332293536611 0.8218540165811538 0.7596154102570377 1.0 15.642245205935273 -5.255659865258507 24.97494667196755 0.8913324969394779 0.9702515147033072 0.10683721817163849 0.09115530257653748 1040.2493775756654 4495187.1139986655 0.022749887952980597 0.056753688918800706 5.550602599622731e-06 5.255659865258507 0.07891901776382926 ASLGS(ph)LEGEAEAEASS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 8 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 ASLGS(1)LEGEAEAEAS(0.015)S(0.985)PK;AS(0.001)LGS(0.999)LEGEAEAEAS(0.079)S(0.921)PK;AS(0.308)LGS(0.692)LEGEAEAEAS(0.275)S(0.725)PK;ASLGS(1)LEGEAEAEAS(0.208)S(0.792)PK;AS(0.008)LGS(0.992)LEGEAEAEAS(0.311)S(0.689)PK;ASLGS(1)LEGEAEAEAS(0.071)S(0.929)PK;AS(0.001)LGS(0.999)LEGEAEAEAS(0.095)S(0.905)PK;AS(0.008)LGS(0.992)LEGEAEAEAS(0.268)S(0.732)PK 269.0 2.493699999999999e-77 16821800.0 164296.8 207696.0 141224.90000000002 169437.10000000003 176799.80000000002 156399.7 165395.1 175671.3 153449.9 159976.1 True False 161953.897503657 207215.09267280443 129613.9338658786 181898.0695595958 166400.7833657806 149710.8494165076 173958.44899356036 183833.62991761052 136166.75636291696 187627.7557302456 0.8631659898789166 1.1043946662705904 0.6908036253027825 0.9694624809194679 0.8868665657602213 0.7979141936321429 0.9271466703660958 0.9797784405730997 0.7257282155987909 1.0 17.517513735618756 -5.2383429275322735 24.998852954527916 0.8747952875486896 0.9837802670423952 0.13286897473760884 0.11385351926295535 1573.5671217410043 1703172.3321838414 0.026956413631006527 0.0712145004617153 5.776397514804942e-06 5.2383429275322735 0.10898497949370556 ASLGS(ph)LEGEAEAEASSPK ddPTM_PC-9_AZD4547_30min_R2 12 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 AS(0.003)LGS(0.997)LEGEAEAEASSPK;ASLGS(1)LEGEAEAEASSPK;AS(0.004)LGS(0.996)LEGEAEAEASSPK;AS(0.009)LGS(0.99)LEGEAEAEASSPK;AS(0.002)LGS(0.998)LEGEAEAEASSPK;AS(0.003)LGS(0.997)LEGEAEAEASSPK;ASLGS(1)LEGEAEAEASSPK;AS(0.003)LGS(0.997)LEGEAEAEASSPK;ASLGS(1)LEGEAEAEASSPK;AS(0.168)LGS(0.832)LEGEAEAEASSPK;AS(0.015)LGS(0.985)LEGEAEAEASSPK;ASLGS(1)LEGEAEAEASSPK 189.87 1.1754e-42 423016800.0 144552.2 219152.0 232387.3 284422.8 292065.4 284967.8 240188.8 309422.1 226475.7 239384.7 True False 190516.7927274571 289988.59824906226 229305.69256283576 218853.51774845517 251517.1606257757 267148.7184174411 261565.13789263958 261608.02425750374 238446.74314269493 231003.91451603215 0.8247340445576512 1.2553406242340384 0.9926485143909606 0.9474017711213559 1.088800426402817 1.1564683610541173 1.132297426390523 1.1324830785036226 1.0322194913547504 1.0 17.81755777371891 -6.493321525479089 21.93487206863749 1.1039141392009215 1.021535312322657 0.11449029738260486 0.10956637453095354 346.4531210017818 257107.42331316843 0.03299567880374018 0.03731510066096196 3.2112822184108394e-07 6.493321525479089 -0.08237882687826459 ASLGS(ph)LEGEAEAEASSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 14 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 AS(0.01)LGS(0.983)LEGEAEAEAS(0.005)S(0.002)PK;ASLGS(1)LEGEAEAEASSPK;ASLGS(1)LEGEAEAEASSPK;ASLGS(1)LEGEAEAEASSPK;ASLGS(1)LEGEAEAEASSPK;AS(0.001)LGS(0.999)LEGEAEAEASSPK;AS(0.002)LGS(0.998)LEGEAEAEASSPK;AS(0.003)LGS(0.997)LEGEAEAEASSPK;AS(0.003)LGS(0.997)LEGEAEAEASSPK;ASLGS(1)LEGEAEAEASSPK;AS(0.017)LGS(0.983)LEGEAEAEASSPK;ASLGS(1)LEGEAEAEASSPK;AS(0.002)LGS(0.998)LEGEAEAEASSPK;ASLGS(1)LEGEAEAEASSPK 250.38 6.359199999999999e-54 724097100.0 151905.49999999997 206584.5 191187.5 251585.09999999998 266386.2 216118.19999999998 229772.2 214657.30000000002 176705.5 172353.7 True False 177620.10087961532 227092.84389060206 195746.13508263146 237489.6024968987 214189.73637933686 204784.58113765286 208006.51380932992 209022.77332320935 179289.48364353727 203600.0614588613 0.8723970887184854 1.115386912279924 0.9614247347473577 1.1664515265624564 1.0520121400975866 1.0058178748587012 1.0216426867403425 1.026634136677035 0.8805964121958963 1.0 17.63537847134345 -8.152409730680956 7.8037547413210895 0.9408338121754686 1.0333254885356844 0.1581439156720359 0.07994451856044134 0.4335392052720157 27.141108224083926 0.051490491730549204 0.019295811271161593 7.040285470261167e-09 8.152409730680956 0.09249167636021582 ASLGS(ph)LEGEAEAEASSPK ddPTM_PC-9_Lapatinib_30min_R1 10 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ASLGS(1)LEGEAEAEASSPK;ASLGS(1)LEGEAEAEASSPK;AS(0.037)LGS(0.958)LEGEAEAEAS(0.004)S(0.001)PK;AS(0.047)LGS(0.953)LEGEAEAEASSPK;AS(0.002)LGS(0.998)LEGEAEAEASSPK;ASLGS(1)LEGEAEAEASSPK;ASLGS(1)LEGEAEAEASSPK;AS(0.048)LGS(0.952)LEGEAEAEASSPK;AS(0.002)LGS(0.998)LEGEAEAEASSPK;ASLGS(1)LEGEAEAEASSPK 207.16 2.9691e-20 684369900.0 179169.3 232490.7 179744.2 170842.2 171250.5 169289.1 142698.6 155888.6 151182.1 124534.79999999999 True False 176614.31292637443 231952.38206833648 164966.32570867665 183406.5053008721 161177.88228143717 162048.9998251668 150086.83527838776 163131.75345531313 134154.37987990986 146060.47424780956 1.209186221227288 1.5880571610003178 1.129438518930118 1.2556888250937785 1.10350101977609 1.109465107926671 1.0275663970784252 1.116878158142497 0.9184851724656217 1.0 17.156206294456254 -5.992574149876792 0.6572647218217275 1.0085889544691828 1.4175037752955324 0.5581911227605723 0.11566456409872157 0.7186545913823892 0.5926631610205384 0.06610770721845684 0.17911492391924771 1.0172456704882781e-06 5.992574149876792 0.40891482082634956 ASLGSLEGEAEAEAS(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 5 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ASLGS(0.006)LEGEAEAEAS(0.981)S(0.013)PK;ASLGSLEGEAEAEAS(0.905)S(0.095)PK;ASLGSLEGEAEAEAS(0.832)S(0.168)PK;ASLGSLEGEAEAEAS(0.703)S(0.297)PK;ASLGSLEGEAEAEAS(0.857)S(0.143)PK 208.38 2.3374e-20 276925800.0 616355.75 625558.0 474952.1 433733.5 523517.5 549350.5 613758.19 523790.8 539506.0 502852.3 True False 812344.0575039798 827757.3900465737 468653.9248258105 333742.94269077486 450836.13169483416 514999.5263920361 668381.4799028374 442850.9673751733 568023.1857366714 485247.5940333287 1.6740815771014101 1.7058454286529035 0.9658037063726719 0.687778665560683 0.9290847337284664 1.0613128900061355 1.3774029755558774 0.9126288781655588 1.1705842393062074 1.0 18.888361534187105 -5.259974407874416 24.76744675905064 1.0100712881740679 1.6899635833556301 0.7194673632214827 0.1690605231362923 59.9582182829266 1013650.3864405882 0.04735398179090096 0.11228303131094995 5.495732581821585e-06 5.259974407874416 0.6798922951815622 ASLGSLEGEAEAEAS(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ASLGSLEGEAEAEAS(0.61)S(0.39)PK;ASLGSLEGEAEAEAS(0.5)S(0.5)PK;ASLGSLEGEAEAEAS(0.584)S(0.416)PK;ASLGSLEGEAEAEAS(0.578)S(0.422)PK;ASLGSLEGEAEAEAS(0.5)S(0.5)PK;ASLGSLEGEAEAEAS(0.942)S(0.058)PK;ASLGSLEGEAEAEAS(0.8)S(0.2)PK 322.37 1.2354999999999997e-176 202327300.0 352319.5 370227.3 254459.6 303961.8 341945.8 244119.4 396112.6 257590.0 239021.6 276318.4 True False 411960.23272268364 406981.01959701424 260526.88190740754 286931.80580345175 274943.97516846407 231317.34891635715 358589.94692112214 250828.53543916505 242516.83871555913 326412.73858474934 1.2620838099298715 1.2468294630950694 0.7981516990941967 0.8790459803974628 0.8423199914334164 0.7086652007495052 1.0985782861167912 0.7684397873891196 0.7429760240579348 1.0 18.31633783546691 -5.2560826717425 24.21289331592454 0.8504135719643413 1.2544567306471854 0.669588929793957 0.11227196271911159 153.87379921573373 695517.0089247613 0.028033926847936222 0.06963654179606611 5.545201451642574e-06 5.2560826717425 0.40404315868284413 ASLGSLEGEAEAEAS(ph)SPKGK ddPTM_PC-9_AZD4547_30min_R2 4 ASLGSLEGEAEAEASSPKGK 20 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ASLGSLEGEAEAEAS(0.5)S(0.5)PKGK;ASLGSLEGEAEAEAS(0.55)S(0.45)PKGK;ASLGSLEGEAEAEAS(0.598)S(0.402)PKGK;ASLGSLEGEAEAEAS(0.846)S(0.154)PKGK 121.14 4.9467000000000004e-06 560950000.0 129768.0 76622.9 128395.0 241201.0 189926.0 118633.0 93631.5 108401.0 92695.0 155727.0 True False 171031.52465792114 101389.75398252372 126692.39840819746 185595.83596830198 163558.05326139613 111214.85975614213 101964.5221117498 91650.11625717019 97594.66845940688 150275.04512960953 1.1381232626508915 0.6746945502167501 0.8430701072086023 1.2350409597829692 1.0883913102160792 0.7400753708656106 0.6785193245079862 0.6098824736876546 0.6494402871430398 1.0 17.19724592775706 -6.8503016169086255 6.516005894585182 0.7039614267619791 0.9821900953560575 0.3433305370026083 0.17722060000540665 0.25272545527986373 15.285142068545499 0.06544216963676622 0.05783431600390377 1.4115568798535324e-07 6.8503016169086255 0.27822866859407835 ASLGSLEGEAEAEAS(ph)SPKGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASLGSLEGEAEAEASSPKGK 20 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ASLGSLEGEAEAEAS(0.633)S(0.367)PKGK 83.064 0.00045284 8577400.0 21756.0 14055.0 15663.0 24653.0 28092.0 32935.0 30661.0 36057.0 31420.0 23521.0 True False 25438.861099413196 15450.287513740968 16036.465322258287 23271.772336104386 22587.574260109326 31207.830621246114 27756.568113583246 35110.54195554944 31879.458059199944 27785.171107866463 0.9155553154830497 0.5560623490048159 0.5771591349933449 0.8375608789940381 0.8129363023326638 1.1231829561204552 0.9989705661997842 1.2636431792787857 1.1473551102290789 1.0 14.762027504333453 -6.586148160088684 1.4530157891568842 1.133495628573774 0.6822605434242172 0.6841817331467344 0.12463539506143229 0.21618339530159333 0.9432194907807178 0.05194934167740747 0.05457266835169672 2.593294505629883e-07 6.586148160088684 -0.4512350851495569 ASLGSLEGEAEAEAS(ph)SPKGK ddPTM_PC-9_Lapatinib_30min_R1 2 ASLGSLEGEAEAEASSPKGK 20 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ASLGSLEGEAEAEAS(0.585)S(0.415)PKGK;ASLGSLEGEAEAEAS(0.615)S(0.385)PKGK 95.59100000000001 0.00024895 174058000.0 97008.0 32224.0 40231.0 45617.0 36657.0 38344.0 29098.9 24740.0 45862.0 25438.0 True False 95624.64813091156 32149.38730783664 36923.36247615099 48971.82635385104 34500.90733043488 36704.11650422966 30605.498659988803 25889.51071781037 40696.53861172993 29834.924405995615 3.2051245322309203 1.0775756248062058 1.2375886050085279 1.6414261919165338 1.1563933214961184 1.2302399699344846 1.0258279271469626 0.8677585491923562 1.3640570379173331 1.0 14.864714501029713 -4.759566247592556 24.9999998911047 1.1863072803227666 3.205127070269171 0.8984606750705177 0.20443659680589865 14.74608206747298 196756.91709355876 0.053177440857654995 0.3348888562029294 1.7395373275241156e-05 4.759566247592556 2.0188197899464044 ASLGSLEGEAEAEASS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ASLGSLEGEAEAEAS(0.207)S(0.793)PK;ASLGSLEGEAEAEAS(0.046)S(0.954)PK;ASLGSLEGEAEAEAS(0.263)S(0.737)PK;ASLGSLEGEAEAEAS(0.145)S(0.855)PK 248.75 1.1021999999999999e-53 256414000.0 159402.0 193075.0 124200.0 138006.0 127020.0 148294.0 161254.0 142230.0 135197.0 146678.0 True False 210088.5202324293 255482.7179625904 122553.02684916159 106190.84887144543 109385.46552479663 139021.15273724278 175605.29360960974 120251.62162025532 142343.23740985416 141542.84786530866 1.4842750686516375 1.8049850050050302 0.865836944059387 0.7502381820980175 0.7728081437847513 0.9821842278426847 1.2406511261997124 0.8495775196969758 1.0056547508872165 1.0 17.11087932640079 -5.266211625807 24.998151697986792 0.9284396933305882 1.6446300604646003 0.779440310181206 0.15132426036812568 162.90904255014755 853360.2537069808 0.041709199958897075 0.09154498966782819 5.41736845061581e-06 5.266211625807 0.7161903671340121 ASLGSLEGEAEAEASS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ASLGSLEGEAEAEAS(0.197)S(0.803)PK;ASLGSLEGEAEAEAS(0.372)S(0.628)PK;ASLGSLEGEAEAEAS(0.066)S(0.934)PK;ASLGSLEGEAEAEAS(0.033)S(0.967)PK 334.51 1.0409999999999994e-198 280019800.0 166821.3 226889.7 133742.3 184845.4 175547.6 138820.8 195683.3 143303.8 115825.7 137574.3 True False 195060.85121913656 249413.80995421085 136931.22365249734 174489.11151487203 141150.30795899083 131540.79286794827 177146.76119959392 139542.22709292683 117519.43174180349 162515.4315524407 1.2002604882244308 1.5347084739686991 0.8425736703551883 1.0736771877479685 0.8685348007302571 0.8094049384196632 1.0900304020817368 0.8586398581349436 0.7231278323491523 1.0 17.31021718929889 -5.269115615025372 24.954249949574844 0.9106518914145835 1.3674844883841528 0.6556548362196226 0.133114511267743 286.570905146763 931599.7520020421 0.03368857139919142 0.07228460656655915 5.381265069408818e-06 5.269115615025372 0.45683259696956935 ASLGSLEGEAEAEASS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 11 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ASLGSLEGEAEAEAS(0.134)S(0.866)PK;ASLGSLEGEAEAEAS(0.156)S(0.844)PK;ASLGSLEGEAEAEAS(0.005)S(0.995)PK;ASLGSLEGEAEAEAS(0.101)S(0.899)PK;ASLGSLEGEAEAEAS(0.024)S(0.976)PK;ASLGSLEGEAEAEAS(0.239)S(0.761)PK;ASLGSLEGEAEAEAS(0.387)S(0.613)PK;ASLGSLEGEAEAEAS(0.033)S(0.967)PK;ASLGSLEGEAEAEAS(0.245)S(0.755)PK;ASLGSLEGEAEAEAS(0.137)S(0.863)PK;ASLGSLEGEAEAEAS(0.105)S(0.895)PK 262.24 1.4300999999999997e-66 554760200.0 336216.2 451902.7 264364.3 339039.1 365684.5 316517.3 358528.2 354837.1 301452.1 310536.4 True False 331421.6953334997 450856.34706296993 242629.28772970848 363973.16641528235 344175.65667338914 302980.5929168635 377091.0359040445 371324.1270625203 267499.39006665803 364212.20297625614 0.9099686738258627 1.2378946761769054 0.6661756134116299 0.999343688764351 0.9449866145638914 0.8318793012452016 1.0353607946755918 1.019526869303519 0.7344602621238832 1.0 18.474419735242485 -5.242247133669403 24.999526842935015 0.911653429895304 1.0739316128797605 0.18976157171323216 0.13976210675195183 1359.0610689550397 1770286.4140090898 0.03358891476628424 0.08856803461782474 5.724701762439516e-06 5.242247133669403 0.1622781829844565 ASLGSLEGEAEAEASS(ph)PKGK ddPTM_PC-9_AZD4547_30min_R2 1 ASLGSLEGEAEAEASSPKGK 20 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ASLGSLEGEAEAEAS(0.457)S(0.543)PKGK 59.242 0.007432300000000001 3089800.0 12816.0 13702.0 10039.0 24081.0 17596.0 14089.0 12269.0 11559.0 7981.7 16518.0 True False 16891.22141063986 18130.90354278605 9905.876300633932 18529.497497741228 15153.099129068838 13208.012602768928 13360.917231797644 9772.822149395573 8403.596367036493 15939.709847687895 1.0596944092486091 1.1374676023614065 0.6214590099374243 1.1624739518347624 0.950650875948463 0.828623151172654 0.8382158370176159 0.6131116715912588 0.5272113763259914 1.0 13.960337747578482 -7.150173584236838 1.5784166253009804 0.6913520621345711 0.9845258899114959 0.2792892380552845 0.18292936057422912 0.4782973210493661 2.3540846774739896 0.09639363123101678 0.06372287674050746 7.07662880321696e-08 7.150173584236838 0.2931738277769248 ASLGSLEGEAEAEASS(ph)PKGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ASLGSLEGEAEAEASSPKGK 20 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ASLGSLEGEAEAEAS(0.226)S(0.774)PKGK;ASLGSLEGEAEAEAS(0.231)S(0.769)PKGK;ASLGSLEGEAEAEAS(0.294)S(0.706)PKGK;ASLGSLEGEAEAEAS(0.153)S(0.847)PKGK;ASLGSLEGEAEAEAS(0.211)S(0.789)PKGK 144.18 1.7771e-05 339665000.0 115448.0 60598.8 66162.6 152667.0 140982.0 149110.0 135044.0 199098.0 142710.0 115881.0 True False 134991.0661980628 66614.64838048282 67740.16730705762 144113.56294309243 113357.58914775502 141290.40910684693 122251.65468610731 193871.8884617681 144796.86376920505 136889.30798650862 0.9861330164030567 0.4866314934329871 0.49485360327582256 1.0527744282065903 0.8280967360791041 1.0321508026088646 0.8930694185272385 1.4162675764339134 1.0577660585695692 1.0 17.06265024084827 -6.490789635137986 0.9047577043132876 1.1365331438526503 0.6633164651133983 0.3917970220008342 0.20392506635227456 0.5510103268477072 0.9856251363621552 0.11151399066444384 0.13862388190465044 3.2300583281727435e-07 6.490789635137986 -0.473216678739252 ASLGSLEGEAEAEASS(ph)PKGK ddPTM_PC-9_Lapatinib_30min_R1 1 ASLGSLEGEAEAEASSPKGK 20 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ASLGSLEGEAEAEAS(0.119)S(0.881)PKGK 148.66 6.4737e-05 84879000.0 114750.0 47792.0 58462.0 57200.0 38924.0 43499.0 25237.0 26087.0 47704.0 30769.0 True False 113113.64395742732 47681.34056033175 53655.480029846105 61406.67881360635 36634.566847528346 41638.649171121615 26543.64837441063 27299.097255275617 42331.07317461005 36087.38065288462 3.134437631964449 1.3212746311228987 1.4868211285807797 1.7016108596038502 1.0151628127268912 1.1538285244815423 0.7355382378601336 0.7564721174379134 1.1730159520798122 1.0 15.13920681078033 -1.9472218173967644 0.7800158891108526 1.0204039515123895 199.99999999994174 0.811804316598772 0.28650227101162595 92.62080524438412 0.7400827809322553 0.1093386216318114 31970.345113916683 0.011292190148721898 1.9472218173967644 198.97959604842936 up ASLLT(ph)DEEDVDMALDQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASLLTDEEDVDMALDQR 17 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 ASLLT(1)DEEDVDMALDQR;ASLLT(1)DEEDVDMALDQR 105.0 0.0045538 872150.0 2104.5299999999997 4539.6 6327.9 5303.8 3475.0 5365.4 5797.799999999999 4433.4 3278.7 4436.6 True False 2460.785362637802 4990.261486828777 6478.781134694391 5006.645281151601 2794.098695496224 5084.028978753113 5248.590411562989 4317.027947575588 3326.6447848090024 5240.920459893722 0.4695330489117369 0.9521727194711084 1.2361914637463838 0.9552988486402497 0.5331312918938831 0.9700641361872928 1.0014634741603048 0.8237156012215324 0.6347443755855935 1.0 12.355604498391273 ASLLT(ph)DEEDVDMALDQR ddPTM_PC-9_Lapatinib_30min_R1 3 ASLLTDEEDVDMALDQR 17 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 AS(0.001)LLT(0.999)DEEDVDMALDQR;AS(0.001)LLT(0.999)DEEDVDMALDQR;ASLLT(1)DEEDVDMALDQR 156.11 2.5539e-17 724410.0 4130.099999999999 1755.87 4966.67 2878.86 2615.88 3102.3 1615.16 1417.78 2360.52 2057.16 True False 4071.204016632419 1751.804390895331 4558.329564500628 3090.5809679954345 2462.0190814179564 2969.621860814515 1698.7850817614235 1483.6552346603546 2094.653380222422 2412.7373650066015 1.6873796856962422 0.7260650978025276 1.8892771466189633 1.2809437996940782 1.0204256447991884 1.2308102422935658 0.7040903441874518 0.6149261234060157 0.8681646873805889 1.0 11.236455166306007 -6.856154245525237 1.3412972008606106 0.7704028633295544 1.3677952631103367 0.3869610101699421 0.31511178337964335 0.4381585931545803 1.6404220166993357 0.15275480274797962 0.12669722399872452 1.392662092429605e-07 6.856154245525237 0.5973923997807823 ASLQSGQEGAGDS(ph)PGSQFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASLQSGQEGAGDSPGSQFSK 20 0 Q12778 Q12778 FOXO1 Forkhead box protein O1 1 ASLQS(0.002)GQEGAGDS(0.918)PGS(0.072)QFS(0.008)K;ASLQSGQEGAGDS(0.997)PGS(0.003)QFSK 309.61 1.6723999999999993e-283 0.0 19529.0 17011.2 16289.1 16802.4 20901.8 15090.2 12540.199999999999 12124.2 14055.5 13764.3 True False 22834.873984668135 18699.959512895784 16677.49392075576 15861.016002115795 16806.24233482676 14298.84334722113 11352.3014728142 11805.952596651763 14261.035097106442 16259.658631861159 1.4043882778647454 1.1500831558820555 1.0256976667441127 0.9754827183785879 1.0336159396295417 0.8794061222910444 0.6981881803206567 0.7260885891858602 0.8770808428389529 1.0 13.989009348199115 -3.3950037447290846 0.45945180835422456 0.8156300058735001 3.2472753344776186 0.7611181355737606 0.09514143987935655 7.9222065947246225 0.4773968213933954 0.06398528889053691 13.753874226556363 0.0004027135618896984 3.3950037447290846 2.4316453286041186 ASLQSGQEGAGDS(ph)PGSQFSK ddPTM_PC-9_Lapatinib_30min_R1 2 ASLQSGQEGAGDSPGSQFSK 20 0 Q12778 Q12778 FOXO1 Forkhead box protein O1 1 ASLQSGQEGAGDS(0.914)PGS(0.086)QFSK;ASLQSGQEGAGDS(0.974)PGS(0.026)QFSK 255.63 4.0141e-66 13852900.0 40168.0 50431.0 48710.0 50362.0 47617.0 45672.0 37877.0 42616.0 44843.0 36049.0 True False 39595.19695409096 50314.23011797141 44705.25182603748 54065.78948270703 44816.26167862396 43718.71502663202 39838.08572641563 44596.09493735678 39792.309122275634 42280.02161772687 0.9364989760906312 1.1900237557323297 1.0573611392689966 1.2787550103815157 1.0599867257360558 1.0340277358870116 0.942243740710686 1.0547793787943298 0.94116104012567 1.0 15.367688493918564 -6.724258040746423 3.0143259118976635 0.9911749255414983 1.1205855767706827 0.2899252717372168 0.08886142442912856 0.3096308379751512 5.764667946450581 0.030961933200910677 0.029429208074954635 1.8868699118810415e-07 6.724258040746423 0.12941065122918438 ASLS(ph)APGSEYGSPSVISVSK ddPTM_PC-9_AZD4547_30min_R2 1 ASLSAPGSEYGSPSVISVSK 20 0 O43474-4;O43474-1;O43474 O43474-4 KLF4 Krueppel-like factor 4 1 ASLS(0.999)APGS(0.001)EYGSPSVISVSK 205.65 1.9007999999999999e-72 0.0 9823.1 14678.0 13345.0 17073.0 12177.0 14580.0 11941.0 18950.0 13221.0 11911.0 True False 12946.641466827114 19422.37645606581 13168.0365805319 13137.083625220554 10486.433740320033 13668.310295150193 13003.72586721784 16021.712927679382 13919.835068793556 11493.999515426243 1.1263826355178856 1.6897839981634581 1.1456444349818278 1.1429514685109483 0.9123398453467878 1.1891692075335292 1.1313490878232049 1.3939197497073528 1.2110523451920776 1.0 13.488593273013052 -5.401189866938204 21.461030504556586 1.148134190111636 1.4105529355687096 0.2733684753542299 0.17396464093292138 7.25811462359787 1255.600407381266 0.04470881529338199 0.09306888693234674 3.970179413208328e-06 5.401189866938204 0.26241874545707367 ASLS(ph)APGSEYGSPSVISVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASLSAPGSEYGSPSVISVSK 20 0 O43474-4;O43474-1;O43474 O43474-4 KLF4 Krueppel-like factor 4 1 AS(0.028)LS(0.956)APGS(0.016)EYGSPSVISVSK 149.74 0.00011171 3495500.0 33787.0 38500.0 23804.0 31616.0 29656.0 25092.0 23957.0 25461.0 24196.0 18909.0 True False 39506.47177633174 42322.025562364084 24371.577637172708 29844.65802045498 23845.119687377264 23776.131348058512 21687.61952634009 24792.675728159407 24549.820725665246 22337.052016438356 1.7686520023885877 1.8947005867747597 1.0910829960568251 1.3361054985452692 1.0675141764378346 1.0644256605822964 0.9709257743761204 1.1099349954467537 1.0990627011835967 1.0 14.447151174954156 -5.264068028037298 24.988919172970025 1.098787892814402 1.8316763403173881 0.9041097189424094 0.09628814683636112 58.867295334892894 559620.6989923499 0.026210329355898107 0.058879605416818595 5.4441736843891466e-06 5.264068028037298 0.7328884475029862 ASLS(ph)APGSEYGSPSVISVSK ddPTM_PC-9_Lapatinib_30min_R1 1 ASLSAPGSEYGSPSVISVSK 20 0 O43474-4;O43474-1;O43474 O43474-4 KLF4 Krueppel-like factor 4 1 AS(0.027)LS(0.762)APGS(0.207)EY(0.002)GS(0.002)PSVISVSK 91.589 0.00064957 3569900.0 25482.0 24534.0 21014.0 16947.0 21695.0 17043.0 22966.0 27795.0 24568.0 20189.0 True False 25118.62200717352 24477.193030364477 19286.310036385792 18193.338913534735 20418.94275401109 16314.110619173438 24155.067106498955 29086.45717063618 21800.893127490763 23678.641749848484 1.060813465254368 1.0337245391417396 0.8145023789850278 0.768343856279305 0.8623358961939507 0.688980001113359 1.020120468128351 1.2283836834020387 0.9206986345671733 1.0 14.531298707266387 -7.503228022823349 24.576243211580252 1.0695751137040908 0.8697544650355394 0.3006502530331395 0.12715586404684737 718.3178383970911 898370.4475940146 0.056421462681148546 0.03740959302297775 3.138860227850104e-08 7.503228022823349 -0.19982064866855132 ASLS(ph)DLSSLDDVEGMSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASLSDLSSLDDVEGMSVR 18 0 H7BYJ1;A0A087WTM5;Q969K3;Q969K3-2 H7BYJ1 RNF34 E3 ubiquitin-protein ligase RNF34 1 AS(0.428)LS(0.564)DLS(0.004)S(0.004)LDDVEGMSVR 81.71300000000001 0.0026414000000000003 1813500.0 7026.3 9878.9 13205.0 10162.0 15751.0 13530.0 15432.0 12204.0 10083.0 10482.0 True False 8215.713814249262 10859.611904624377 13519.857280241376 9592.656085648518 12664.704619499575 12820.462981796263 13970.169241995249 11883.657931206848 10230.444799838097 12382.303624533659 0.6635044708458828 0.8770267822465362 1.0918693072146792 0.7747069024088638 1.0228068220202888 1.0353859322585548 1.1282366888755235 0.9597291660383113 0.8262149847115702 1.0 13.595992120476714 -4.848010589938043 3.249457833971062 0.9804778575931652 0.6411119126358595 0.462906700919954 0.10340540094993556 0.2600593019074906 4.495255247871878 0.026780714999392177 0.20446410586301014 1.4190229194810474e-05 4.848010589938043 -0.33936594495730565 ASLS(ph)LIEK ddPTM_PC-9_AZD4547_30min_R2 1 ASLSLIEK 8 0 P52292 P52292 KPNA2 Importin subunit alpha-1 1 AS(0.002)LS(0.998)LIEK 89.82700000000001 0.026817 0.0 18068.0 14059.0 20334.0 33217.0 24553.0 22052.0 17769.0 23378.0 18945.0 25664.0 True False 23813.248162253498 18603.29681127056 20064.35787400042 25559.333847534166 21144.239765630104 20673.08495395418 19350.40657688582 19765.467272996768 19946.39402301595 24765.511171513634 0.9615488247884231 0.7511775825030771 0.8101733792226068 1.0320535550638512 0.8537776434007599 0.8347530083583844 0.7813449293606142 0.798104555004375 0.8054101482047807 1.0 14.596044778716685 -6.5203339907941436 24.061605550497994 0.8292676426454517 0.8820026170834064 0.03773246548365139 0.09172461166046081 195.4484869550062 1848075.9371629136 0.030127421398013294 0.030676601462386224 3.0176301428252244e-07 6.5203339907941436 0.05273497443795472 ASLS(ph)LIEK ddPTM_PC-9_Lapatinib_30min_R1 1 ASLSLIEK 8 0 P52292 P52292 KPNA2 Importin subunit alpha-1 1 ASLS(1)LIEK 87.29799999999999 0.030864999999999997 0.0 11110.0 15111.0 14902.0 13008.0 14722.0 12624.0 12491.0 13210.0 13176.0 10801.0 True False 10951.569362675522 15076.011407917067 13676.815083383504 13964.651713415924 13856.080904565624 12084.100947981313 13137.722861067601 13823.784825475952 11691.980130568963 12667.938458572167 0.8645107803839062 1.1900919362072997 1.0796401583502049 1.102361821466404 1.093791302340079 0.9539121923823539 1.037084518845096 1.091241867860642 0.9229583936490637 1.0 13.628894143366333 -6.739583812710378 24.849663234234985 1.0089948080958249 1.0757378952952963 0.11306841607129492 0.08764394799179898 483.75807953154396 550028.7507423571 0.027823266131183966 0.02779904711754764 1.8214455258715404e-07 6.739583812710378 0.06674308719947142 ASLSLIEK ddPTM_PC-9_Lapatinib_30min_R1 1 ASLSLIEK 8 0 P52292 P52292 KPNA2 Importin subunit alpha-1 0 92.06200000000001 0.038041000000000005 2883400.0 24475.0 23887.0 24583.0 21137.0 21724.0 19500.0 19342.0 16591.0 22625.0 18966.0 False True 24125.98201183471 23831.69111911292 22561.8806331242 22691.485490964988 20446.237031027296 18666.030456720193 20343.43411886715 17361.878428423286 20076.73424818783 22244.247829393527 1.0845941924794895 1.0713642152296894 1.0142793231835403 1.0201057668931597 0.919169629283201 0.8391396553339474 0.9145480788963948 0.7805109240637625 0.9025584682462696 1.0 14.441144695363647 -6.188304636741753 1.614722454037558 0.87347844228571 1.0643819514654203 0.6529686414193385 0.05577819329545529 0.2109383170300937 1.0929160081320566 0.019007313383031955 0.02727997267241874 6.481796071524609e-07 6.188304636741753 0.19090350917971022 ASLSPDASDFEHIT(ph)AETPSRPLSSTSNPFK ddPTM_PC-9_AZD4547_30min_R2 1 ASLSPDASDFEHITAETPSRPLSSTSNPFK 30 1 Q5M775;Q5M775-4;Q5M775-2;Q5M775-5;Q5M775-3 Q5M775 SPECC1 Cytospin-B 1 ASLSPDAS(0.029)DFEHIT(0.89)AET(0.026)PS(0.013)RPLS(0.011)S(0.011)T(0.011)S(0.011)NPFK 61.522 0.00046148 10931000.0 22488.0 27017.0 51181.0 82320.0 65058.0 50516.0 40982.0 63444.0 43701.0 51328.0 True False 29638.716220542206 35749.71690376958 50502.306498928665 63342.39583132179 56025.81968282338 47357.22653428029 44629.31860734624 53640.187598083976 46010.94564264026 49531.02234302727 0.5983869263848255 0.7217641634001574 1.0196096125207101 1.278842891484125 1.131125848661398 0.9561124381061157 0.9010377031644076 1.0829614463961328 0.9289318787726871 1.0 15.596044778716685 -5.190498250859453 3.4112217609880444 1.0460983049674877 0.6255795341863866 0.6813946303506571 0.10456218570171058 0.14823642248724078 3.3393704256583243 0.030271321170347705 0.09496215607603158 6.449139172826651e-06 5.190498250859453 -0.4205187707811011 ASLTLFCPEEGDWK ddPTM_PC-9_Lapatinib_30min_R1 1 ASLTLFCPEEGDWK 14 0 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 0 127.83 0.00012703 2892300.0 19166.0 21380.0 17788.0 17822.0 25439.0 15095.0 21536.0 19352.0 22604.0 24141.0 False True 18892.689325386065 21330.49592358329 16325.539303665675 19132.689332449176 23942.72803499832 14449.422038163648 22651.0287035427 20251.16456794932 20058.099489327637 28313.739684139473 0.6672622386215268 0.7533620129852366 0.5765942431409287 0.6757386889152883 0.8456222421374572 0.5103325169814212 0.8000013052401955 0.7152416033298995 0.7084228262705825 1.0 14.789214692814506 -14.522870524186683 0.27492512783904 3.1718226515786467 0.6745858241522323 0.5023228018061452 0.09220812200545966 177.8437402467082 1.714006983503375 219.6345709154539 0.10499464393483063 3.000056789840601e-15 14.522870524186683 -2.4972368274264145 ASLVALPEQTAS(ph)EEETPPPLLTK ddPTM_PC-9_AZD4547_30min_R2 2 ASLVALPEQTASEEETPPPLLTK 23 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 AS(0.002)LVALPEQT(0.318)AS(0.652)EEET(0.028)PPPLLTK;ASLVALPEQT(0.402)AS(0.595)EEET(0.003)PPPLLTK 104.3 0.00075432 0.0 11436.2 9620.4 15995.599999999999 19343.2 18918.7 11998.3 10591.9 16173.7 13175.6 13275.3 True False 15072.673712262762 12730.00616282433 15783.487892660616 14883.92408946092 16292.165065532778 11248.044404273009 11534.558580770836 13674.426299652147 13872.035317479496 12810.535787686844 1.1765841774354378 0.9937137972839577 1.2320708637207272 1.161850240781261 1.2717785840926643 0.8780307545828285 0.9003962653816209 1.0674359391584272 1.0828614468110647 1.0 13.645043195750011 -6.762290321597335 24.99999950870975 0.9846253451887308 1.1608682118451885 0.5041348733692184 0.08986702212483853 21.59549216779709 634444.1843387355 0.03261065457240609 0.030451028367254118 1.7286603803852604e-07 6.762290321597335 0.17624286665645772 ASLVALPEQTAS(ph)EEETPPPLLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASLVALPEQTASEEETPPPLLTK 23 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 ASLVALPEQT(0.104)AS(0.764)EEET(0.131)PPPLLTK;ASLVALPEQT(0.034)AS(0.877)EEET(0.09)PPPLLTK 93.147 7.2299e-06 2430300.0 34825.0 34938.0 39663.0 42939.0 50501.0 42529.0 44594.0 41455.0 38755.0 33430.0 True False 40720.18467489722 38406.41374280197 40608.71634276515 40533.2670401163 40605.69157446181 40298.704371974345 40369.73348739867 40366.850175203224 39321.71855774328 39490.59436826563 1.031136282608592 0.9725458519222769 1.0283136273937177 1.0264030635276675 1.0282370327424666 1.020463353784265 1.0222619875237813 1.0221889748927595 0.9957236447507598 1.0 15.269221461343564 ASLVS(ph)EEEEDEEEDKATPR ddPTM_PC-9_AZD4547_30min_R2 2 ASLVSEEEEDEEEDKATPR 19 1 Q96GN5-5;Q96GN5-4;Q96GN5-2;Q96GN5;C9J8L0;C9IZR6 Q96GN5-5 CDCA7L Cell division cycle-associated 7-like protein 1 AS(0.01)LVS(0.99)EEEEDEEEDKATPR;ASLVS(1)EEEEDEEEDKATPR 131.3 1.8892e-05 33145000.0 24299.1 25365.7 26110.2 23242.6 29443.0 40497.0 30814.0 31106.0 31397.0 31644.0 True False 32025.708347322012 33564.66647170108 25763.961687898398 17884.377664590353 25355.347673174223 37964.71618811368 33556.38630537229 26299.282444770186 33056.58132175411 30536.15319168399 1.0487800524934385 1.099177956732345 0.8437199514349694 0.5856788034931939 0.8303386321784412 1.2432710809969585 1.0989067972881015 0.861250671611523 1.0825391500444959 1.0 14.898230708847482 -6.719341977589883 24.999720282344033 1.0511295358771 0.8750922717857266 0.2377977901166699 0.15683912837272954 246.3552435105439 146298.32193113668 0.0578011365411946 0.05780063713988407 1.9083499699858812e-07 6.719341977589883 -0.17603726409137344 ASLVS(ph)EEEEDEEEDKATPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASLVSEEEEDEEEDKATPR 19 1 Q96GN5-5;Q96GN5-4;Q96GN5-2;Q96GN5;C9J8L0;C9IZR6 Q96GN5-5 CDCA7L Cell division cycle-associated 7-like protein 1 AS(0.012)LVS(0.988)EEEEDEEEDKATPR;AS(0.006)LVS(0.994)EEEEDEEEDKATPR 93.06200000000001 0.00039681 22521300.0 34987.0 31382.0 28845.0 35421.0 41759.0 29573.0 44937.0 32485.0 29107.0 25891.0 True False 40909.60807525137 34497.39756358724 29532.774195271668 33436.47620643141 33576.62371948972 28022.139819708846 40680.24204429372 31632.30317070261 29532.63480996601 30584.833346956762 1.337578256882081 1.1279249807329679 0.965601932835453 1.0932371553941587 1.0978194106403605 0.9162103158066445 1.3300789179660992 1.0342480147550017 0.9655973755012973 1.0 14.900528794576429 -4.808160542425425 3.5006569095253193 1.0592613899081644 1.362995979162586 0.3848222002999284 0.10887948499371593 0.2860483286164826 5.843243699151349 0.02711250759570615 0.22180624762438267 1.55539055560966e-05 4.808160542425425 0.30373458925442165 ASLVS(ph)EEEEDEEEDKATPR ddPTM_PC-9_Lapatinib_30min_R1 2 ASLVSEEEEDEEEDKATPR 19 1 Q96GN5-5;Q96GN5-4;Q96GN5-2;Q96GN5;C9J8L0;C9IZR6 Q96GN5-5 CDCA7L Cell division cycle-associated 7-like protein 1 AS(0.002)LVS(0.998)EEEEDEEEDKATPR;ASLVS(1)EEEEDEEEDKATPR 139.2 7.138899999999999e-05 35473000.0 31843.0 47822.0 40161.0 38313.0 48837.0 45967.0 43875.0 46605.0 47290.0 50969.0 True False 31388.912980708985 47711.27109717491 36859.11760594315 41130.66582842134 45964.50367723624 44001.09856431063 46146.632817976235 48770.43843991726 41963.70221422328 59778.92373807648 0.5250832738013258 0.7981286398902658 0.6165905188832558 0.6880462754504721 0.768908183737656 0.7360637464318199 0.7719548953435391 0.8158467130255925 0.7019815612286491 1.0 15.867349302465135 -14.522878745273054 0.08785440296429967 1.8923437320755867 0.4841215331323441 0.6322026224576549 0.07280500666669448 140.78887651139715 0.8598375723718035 23.782578672122057 1.7618364692731698 3.0000000000503106e-15 14.522878745273054 -1.4082221989432426 ASMSEFLES(ph)EDGEVEQQR ddPTM_PC-9_AZD4547_30min_R2 5 ASMSEFLESEDGEVEQQR 18 0 J3QQW9;Q15022 J3QQW9 SUZ12 Polycomb protein SUZ12 1 ASMSEFLES(1)EDGEVEQQR;ASMS(0.001)EFLES(0.999)EDGEVEQQR;ASMSEFLES(1)EDGEVEQQR;ASMSEFLES(1)EDGEVEQQR;ASMSEFLES(1)EDGEVEQQR 142.4 1.4669e-08 46505600.0 80434.70000000001 81192.2 112229.0 143723.0 117019.8 105488.0 103988.2 127049.0 99528.0 104423.1 True False 106011.26145430662 107435.99084999229 110740.77013087411 110589.88284821482 100773.62067877961 98891.81868414307 113242.94834816337 107416.4963455801 104788.84688956091 100767.27905291783 1.0520405279439462 1.06617933777464 1.0989754925576458 1.09747810884264 1.0000629333839455 0.9813882007492744 1.12380674969594 1.0659858771136457 1.0399094614287556 1.0 16.62066772030208 -6.239250373923189 24.890142808344056 1.0402320189817291 1.0792268018665518 0.21528420715204666 0.03996913715693235 1470.4127031909825 1649408.7529403998 0.012684274073040002 0.016359690957199167 5.764340491657448e-07 6.239250373923189 0.03899478288482272 ASMSEFLES(ph)EDGEVEQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ASMSEFLESEDGEVEQQR 18 0 J3QQW9;Q15022 J3QQW9 SUZ12 Polycomb protein SUZ12 1 ASMSEFLES(1)EDGEVEQQR;ASMSEFLES(1)EDGEVEQQR;ASMSEFLES(1)EDGEVEQQR;ASMSEFLES(1)EDGEVEQQR 175.7 1.9407e-08 29339600.0 81337.4 80975.0 106256.3 107556.0 124949.0 106525.2 109295.0 113009.0 101371.5 86975.1 True False 95106.2153331223 89013.66285486832 108789.85317126183 101529.98602125679 100466.14040390147 100938.83098510298 98941.78637272347 110042.63349293284 102853.86641146381 102742.9971354871 0.9256710236679763 0.866372067553043 1.0588541915688983 0.9881937343853158 0.9778393000490035 0.9824400085583939 0.9630027265240182 1.0710475318120196 1.0010790932624878 1.0 16.64868053897927 -5.253145357211413 24.99956576998258 1.0039247525924133 0.8960215391719063 0.6068811541715022 0.03516891051865939 410.6536207955542 1237771.3804204073 0.009073966308984169 0.023182715871841425 5.582833075206988e-06 5.253145357211413 -0.10790321342050702 ASMSEFLES(ph)EDGEVEQQR ddPTM_PC-9_Lapatinib_30min_R1 4 ASMSEFLESEDGEVEQQR 18 0 J3QQW9;Q15022 J3QQW9 SUZ12 Polycomb protein SUZ12 1 ASMSEFLES(1)EDGEVEQQR;ASMSEFLES(1)EDGEVEQQR;ASMS(0.002)EFLES(0.998)EDGEVEQQR;ASMSEFLES(1)EDGEVEQQR 193.3 1.9286e-14 30393200.0 124428.0 104640.0 133799.0 105985.0 121086.0 119677.0 104861.0 106781.0 125162.0 98451.0 True False 122653.63390269924 104397.71250906255 122798.56269907599 113779.49045559565 113963.95954423548 114558.69369071278 110290.18949118658 111742.43508320581 111064.9375457097 115468.12417228827 1.0622293795964812 0.9041258205017021 1.0634845207656625 0.9853757586451042 0.9869733345125755 0.9921239693803414 0.9551570208815745 0.9677340468134442 0.9618666479762966 1.0 16.81713511442863 -7.117239372729088 5.271165944548003 0.9686020571626676 0.997033595484982 0.08893103881973508 0.04330522021334524 0.5907359386523069 23.234424385680345 0.01574462001027569 0.012161169813092503 7.634148915699746e-08 7.117239372729088 0.028431538322314487 ASNDMYHSR ddPTM_PC-9_AZD4547_30min_R2 1 ASNDMYHSR 9 0 P01034 P01034 CST3 Cystatin-C 0 82.494 0.010648000000000001 342310.0 864.66 2281.1 3288.3 4232.4 4046.5 2017.5 890.26 3593.3 2988.9 2326.1 False True 1139.6038939547332 3018.4209656582434 3244.694993462948 3256.685569928157 3484.7133226743013 1891.345406067593 969.4914153378568 3038.0380508195435 3146.8871520397133 2244.663947009738 0.5076946575779743 1.3447095141699394 1.4455148164986638 1.4508566301279078 1.5524432186459418 0.8425962418949957 0.4319093807468949 1.3534489449374862 1.401941326777171 1.0 11.13228375712404 -6.776103353638875 24.992260055568906 0.9921903924313631 1.2858188021333883 0.10322054652588208 0.3698016035188664 550.6341821526946 938456.9180436665 0.13770587856284003 0.12195906038412843 1.6745443196288475e-07 6.776103353638875 0.2936284097020252 ASNGDAWVEAHGK ddPTM_PC-9_AZD4547_30min_R2 1 ASNGDAWVEAHGK 13 0 P38646;D6RJI2;A0A3B3ITI4 P38646 HSPA9 Stress-70 protein, mitochondrial 0 94.551 0.0031384 3123700.0 36305.0 40522.0 42383.0 60453.0 52770.0 42714.0 45244.0 59686.0 41270.0 45934.0 False True 47849.234809088615 53619.944049100624 41820.97372743974 46516.49483953951 45443.79637650392 40043.08682764368 49270.62835075822 50462.90014783491 43451.447945625114 44325.86464122148 1.0794879061330374 1.2096762123673495 0.9434891809994772 1.0494210370412227 1.025220754165341 0.903379711862519 1.1115548167996319 1.1384526970040467 0.9802729917921739 1.0 15.43586115283779 -5.25683764592701 24.998859883899186 1.0244072352838611 1.1445820560324778 0.31877809043251537 0.07310325966600976 474.9795589199887 2580295.968240429 0.01908924844659062 0.047005008128553044 5.5355700900892e-06 5.25683764592701 0.12017482074861663 ASNGDAWVEAHGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASNGDAWVEAHGK 13 0 P38646;D6RJI2;A0A3B3ITI4 P38646 HSPA9 Stress-70 protein, mitochondrial 0 92.06299999999999 0.004031900000000001 5085400.0 37878.0 39907.0 40786.0 47909.0 52107.0 37992.0 43569.0 44265.0 37427.0 43846.0 False True 44289.99727539866 43868.703223824996 41758.49292176635 45224.8140530737 41897.00740322927 35999.632638906376 39441.82890775603 43103.09065264433 37974.299070072426 51794.93271525499 0.8551029020326166 0.8469690165444407 0.80622738041452 0.8731513235416133 0.8089016667626538 0.6950415948373947 0.7614997614648771 0.8321874050808318 0.7331662979241207 1.0 15.660523340315153 -6.515563825920465 24.959135733517094 0.7868508729103372 0.8424750839545776 0.03631599456800394 0.07866142155990856 801.0626732609348 2733307.5481492314 0.024029916954752727 0.024989135012875932 3.0509576133862686e-07 6.515563825920465 0.055624211044240424 ASNGDAWVEAHGK ddPTM_PC-9_Lapatinib_30min_R1 2 ASNGDAWVEAHGK 13 0 P38646;D6RJI2;A0A3B3ITI4 P38646 HSPA9 Stress-70 protein, mitochondrial 0 ; 94.551 0.0031384 8614600.0 169836.0 135550.0 121472.0 115512.0 109584.0 97228.0 94548.0 79282.0 145180.0 83869.0 False True 167414.10749589215 135236.1423031674 111485.04105548008 124007.137816736 103138.4845704335 93069.78508953801 99443.232813083 82965.7311531708 128828.2995868246 98365.64490158188 1.7019570975557123 1.3748310442988068 1.1333737624251292 1.260675289028088 1.0485214088071806 0.9461614894372669 1.0109549214319622 0.8434421513342467 1.3096879476134338 1.0 16.58586690868676 -1.5648786222709605 0.5589460277483884 1.0110109780981307 32.81398910378432 0.7354534740294912 0.12378538831638572 64.185419057881 0.6010819991968838 0.058666160683957934 2452.0062933436825 0.02723462361926723 1.5648786222709605 31.80297812568619 ASNT(ph)STPTKGNTETSASASQTNHVK ddPTM_PC-9_AZD4547_30min_R2 1 ASNTSTPTKGNTETSASASQTNHVK 25 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YCQ1;A0A2R8Y7Y0 Q14004 CDK13 Cyclin-dependent kinase 13 1 AS(0.073)NT(0.267)S(0.221)T(0.183)PT(0.183)KGNT(0.059)ET(0.011)S(0.002)AS(0.001)ASQTNHVK 42.321999999999996 0.046345 30466000.0 7382.6 1965.6 16739.0 29910.0 20114.0 16366.0 14617.0 25222.0 13603.0 22083.0 True False 9730.113232380603 2600.9417605970134 16517.0299229317 23014.71160489348 17321.518292912617 15342.631432813998 15917.884683118917 21324.519443901307 14322.0268089251 21309.880891542063 0.456601014426247 0.1220533222984523 0.7750878574589942 1.080001888421069 0.8128397517129045 0.7199773434164769 0.7469720156641869 1.0006869373148422 0.6720838507647193 1.0 14.379234908959985 -5.346673075272214 5.801021513794091 0.8534366970547611 0.2923393536944092 0.7007229322976413 0.14729208920536527 0.10691175896315495 5.676266152167887 0.0376499846982178 0.08035119670251153 4.501185640457327e-06 5.346673075272214 -0.5610973433603519 down ASNTS(ph)TPTKGNTETSASASQTNHVK ddPTM_PC-9_AZD4547_30min_R2 1 ASNTSTPTKGNTETSASASQTNHVK 25 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YCQ1;A0A2R8Y7Y0 Q14004 CDK13 Cyclin-dependent kinase 13 1 AS(0.006)NT(0.156)S(0.424)T(0.32)PT(0.092)KGNT(0.001)ETSASASQTNHVK 51.39 0.0092557 5870000.0 1238.4 1034.2 6274.7 14250.0 10797.0 8448.9 4760.5 10787.0 5941.6 10093.0 True False 1632.1854396798067 1368.4849251167238 6191.493378183849 10964.882660305322 9298.022919786099 7920.588947372731 5184.175277689515 9120.117010600401 6255.660845983188 9739.64714207011 0.1675815782513959 0.14050662258652008 0.635699968168239 1.1257987584522282 0.9546570614066265 0.813231612176173 0.5322754717978054 0.9363909059093459 0.6422882425547073 1.0 13.249653790480282 -5.369849630563479 3.643254824233522 0.8457468532052029 0.14923441538899523 0.7392734107673549 0.16440577629996803 0.11769927828667441 2.811617129677777 0.045844219389739836 0.10677501275089481 4.267272425938066e-06 5.369849630563479 -0.6965124378162078 down ASNTS(ph)TPTKGNTETSASASQTNHVK ddPTM_PC-9_Lapatinib_30min_R1 1 ASNTSTPTKGNTETSASASQTNHVK 25 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YCQ1;A0A2R8Y7Y0 Q14004 CDK13 Cyclin-dependent kinase 13 1 AS(0.011)NT(0.121)S(0.39)T(0.311)PT(0.144)KGNT(0.016)ET(0.006)S(0.001)ASASQTNHVK 60.028999999999996 0.0016169 2924500.0 4557.7 2997.6 10150.0 4733.6 8434.4 7157.6 4543.4 5516.9 9628.6 5168.7 True False 4492.706362220184 2990.659241371996 9315.506180133047 5081.7247348266965 7938.305174668409 6851.486133180538 4778.635020973062 5773.23531443363 8544.125674347022 6062.102908140162 0.7411135096679735 0.4933369305486638 1.536678990985823 0.8382775435901924 1.3094969344728364 1.1302160713867784 0.7882800891677926 0.9523486159697748 1.409432634816214 1.0 12.565602627678972 -5.235423493608932 24.99041864958503 1.1040290373990636 0.6172251258087623 0.4193908555822544 0.2362640905298977 721.3782802545827 692941.3513714331 0.058079815892421845 0.15355774021197902 5.815358680836791e-06 5.235423493608932 -0.48680391159030123 ASNTST(ph)PTKGNTETSASASQTNHVK ddPTM_PC-9_AZD4547_30min_R2 2 ASNTSTPTKGNTETSASASQTNHVK 25 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YCQ1;A0A2R8Y7Y0 Q14004 CDK13 Cyclin-dependent kinase 13 1 AS(0.126)NT(0.126)S(0.136)T(0.35)PT(0.182)KGNT(0.066)ET(0.006)S(0.006)AS(0.001)ASQTNHVK;AS(0.001)NT(0.031)S(0.147)T(0.708)PT(0.111)KGNT(0.001)ETSASASQTNHVK 87.509 6.0552e-06 22321600.0 8834.7 6501.69 18181.0 31537.0 27194.0 22677.2 16650.5 23261.1 18781.2 21119.0 True False 11643.95082682428 8603.234145022376 17939.908060745627 24266.631891792913 23418.582502608417 21259.191099120693 18132.36224370745 19666.631481901997 19773.935889420274 20379.63023812331 0.5713524087911288 0.4221486869240969 0.8802862393050783 1.1907297437810405 1.1491171443729271 1.0431588233309566 0.889729697342006 0.9650141465821329 0.9702794240314533 1.0 14.314840255466072 -5.393311227065728 4.107485468775872 1.0285365727913578 0.49973876714896837 0.840834979495929 0.09118711733334418 0.08742201957878101 2.453313244496902 0.027066101424820597 0.06013196938742863 4.042860656309435e-06 5.393311227065728 -0.5287978056423894 ASNTST(ph)PTKGNTETSASASQTNHVK ddPTM_PC-9_Lapatinib_30min_R1 1 ASNTSTPTKGNTETSASASQTNHVK 25 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YCQ1;A0A2R8Y7Y0 Q14004 CDK13 Cyclin-dependent kinase 13 1 AS(0.036)NT(0.036)S(0.086)T(0.286)PT(0.286)KGNT(0.066)ET(0.091)S(0.108)AS(0.005)ASQTNHVK 48.852 0.019437 17984000.0 8853.3 6005.5 10725.0 6721.6 11728.0 11073.0 5693.8 8015.8 13921.0 6207.5 True False 8727.050318503616 5991.59463372682 9843.231899697228 7215.928886600283 11038.182098135147 10599.43360242373 5988.597104022635 8388.24333111659 12353.070385371164 7280.458104026176 1.1986952185986013 0.8229694544102107 1.3520072169983106 0.9911366542456705 1.51613839959204 1.455874541268512 0.8225577317326876 1.1521587256271408 1.696743557735711 1.0 12.829813515802197 -5.274156542188412 24.884118886214047 1.2463470180380065 1.0108323151143892 0.11195687758598905 0.26750387666740455 1427.5438865337514 2793327.0081169936 0.06979631938259227 0.14680546386242532 5.319164944981682e-06 5.274156542188412 -0.23551470292361731 ASNTSTPTKGNT(ph)ETSASASQTNHVK ddPTM_PC-9_Lapatinib_30min_R1 1 ASNTSTPTKGNTETSASASQTNHVK 25 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YCQ1;A0A2R8Y7Y0 Q14004 CDK13 Cyclin-dependent kinase 13 1 AS(0.169)NT(0.128)S(0.106)T(0.106)PT(0.087)KGNT(0.38)ET(0.017)S(0.006)ASASQTNHVK 67.413 0.0004378 17336000.0 21189.0 12149.0 32040.0 16238.0 23338.0 32714.0 16483.0 20400.0 36717.0 18496.0 True False 20886.8409744133 12120.869736932327 29405.794877976616 17432.196688380063 21965.304724273385 31314.89848005867 17336.409088061595 21347.858473861426 32581.544812849166 21693.008955629164 0.9628374291982823 0.5587454355329097 1.3555424670742158 0.8035859259559539 1.0125522360314871 1.4435479441376757 0.7991703282620429 0.9840893219343749 1.501937554144351 1.0 14.404942557238671 -5.255668255854218 24.992282665512707 1.0980079673738732 0.7607914521625648 0.23572584309966693 0.25226974477611797 678.6670419966267 2938996.8696223465 0.06266026738597066 0.15652616513699547 5.550495362680029e-06 5.255668255854218 -0.33721651521130835 ASNTSTPTKGNTETS(ph)ASASQTNHVK ddPTM_PC-9_AZD4547_30min_R2 1 ASNTSTPTKGNTETSASASQTNHVK 25 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YCQ1;A0A2R8Y7Y0 Q14004 CDK13 Cyclin-dependent kinase 13 1 AS(0.003)NT(0.002)S(0.01)T(0.009)PT(0.251)KGNT(0.102)ET(0.202)S(0.288)AS(0.117)AS(0.015)QT(0.001)NHVK 61.111000000000004 0.0013065 7151300.0 2200.4 2083.2 8137.9 13398.0 12590.0 9515.3 5590.0 8376.9 5972.9 9922.9 True False 2900.081428836761 2756.5536608036714 8029.986128790602 10309.298097036539 10842.095819218945 8920.306786793046 6087.499170735088 7082.442587012004 6288.615300082972 9575.502291295696 0.3028646791169365 0.287875620196909 0.8385968573251771 1.0766326176338423 1.1322743694682842 0.9315758605062175 0.6357367985039004 0.7396418873451759 0.6567399921985749 1.0 13.225132451506981 -5.274228818994777 5.852341046829402 0.8783808782319701 0.29105893149828005 0.6843745147150515 0.15795154461539462 0.09384531535160369 13.210406830290871 0.04725172875811357 0.10942954745879271 5.31827978460871e-06 5.274228818994777 -0.5873219467336901 ASPAPGS(ph)GHPEGPGAHLDMNSLDR ddPTM_PC-9_AZD4547_30min_R2 1 ASPAPGSGHPEGPGAHLDMNSLDR 24 0 O94826 O94826 TOMM70A Mitochondrial import receptor subunit TOM70 1 AS(0.443)PAPGS(0.557)GHPEGPGAHLDMNSLDR 48.641000000000005 0.031218 25554000.0 5230.6 3126.7 9120.1 9458.8 7946.1 6392.9 4473.4 11115.0 8517.5 7390.8 True False 6893.821996761299 4137.344629048984 8999.161515032516 7278.21979700323 6842.921174670034 5993.150952391334 4871.523933875912 9397.432147290572 8967.717661179113 7132.050341584443 0.9665974953325666 0.5801059205829776 1.2617916425185074 1.0204947313070023 0.9594605824318709 0.8403124859407409 0.6830467678378254 1.31763401787807 1.2573828326605532 1.0 12.800101170925318 -7.776071289462236 24.99678449560584 1.2156313675839236 0.9075997562839829 0.3234746962012599 0.19110628345444616 284.2041126465566 485520.00755562005 0.10538911189942995 0.05097166389774199 1.6746679566291445e-08 7.776071289462236 -0.3080316112999407 ASPAPGS(ph)GHPEGPGAHLDMNSLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASPAPGSGHPEGPGAHLDMNSLDR 24 0 O94826 O94826 TOMM70A Mitochondrial import receptor subunit TOM70 1 AS(0.088)PAPGS(0.911)GHPEGPGAHLDMNSLDR 51.777 0.014281 38681000.0 12425.0 11260.0 16985.0 13784.0 26985.0 16092.0 16098.0 16103.0 14270.0 13556.0 True False 14528.307095063834 12377.818385252447 17389.98681597121 13011.72716833095 21697.482963443337 15248.107191653025 14573.08090057281 15680.313312538829 14478.671753812325 16013.595490763042 0.9072482880839626 0.7729568535930745 1.0859514233391305 0.8125425158788587 1.3549413669128132 0.9521975998737094 0.9100442751272724 0.9791875485791771 0.904148713021002 1.0 13.967009648322792 -5.257385089474788 24.991461702993163 1.0002126298803473 0.8401025697033395 0.17134467469328796 0.14054428090351667 588.43454952035 3627194.5693409047 0.035604208091694 0.08732780723609829 5.52859670431813e-06 5.257385089474788 -0.1601100601770078 ASPAPSDSSPGEPFVGGPVS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 ASPAPSDSSPGEPFVGGPVSSPR 23 0 O60346 O60346 PHLPP1 PH domain leucine-rich repeat-containing protein phosphatase 1 1 ASPAPS(0.001)DSSPGEPFVGGPVS(0.763)S(0.236)PR 110.61 0.00098424 0.0 1985.7 2668.4 3067.6 5649.1 4501.0 5054.9 4974.4 6633.9 3864.1 5065.0 True False 2617.1112948741857 3530.908116593949 3026.921619665766 4346.787272724971 3876.1138429153675 4738.816303906359 5417.111963310308 5608.783186856586 4068.3484372834987 4887.675891666016 0.5354510718144438 0.7224104451390704 0.6192967141759491 0.88933623445382 0.7930382310178414 0.9695438913996983 1.108320617688058 1.1475358250370349 0.8323687019060422 1.0 12.254932905950266 -6.102462349961356 0.8611003702827777 1.035172393787513 0.5894920036833419 0.7090585829317437 0.10293995809315105 0.35773238635384913 0.5500032622802965 0.05012950080166253 0.10176005658521808 7.898373193387593e-07 6.102462349961356 -0.44568039010417115 ASPAPSDSSPGEPFVGGPVS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASPAPSDSSPGEPFVGGPVSSPR 23 0 O60346 O60346 PHLPP1 PH domain leucine-rich repeat-containing protein phosphatase 1 1 ASPAPSDSSPGEPFVGGPVS(0.5)S(0.5)PR 110.67 0.00097517 0.0 2454.8 4102.9 4271.9 4257.8 5983.5 3626.9 5164.3 5512.2 4357.6 2468.5 True False 2870.349155489956 4510.2087968785345 4373.758297270969 4019.249269973848 4811.076127914145 3436.6989792074546 4675.10011770581 5367.510590658667 4421.321656230732 2916.0195093647512 0.984338117859594 1.5467004875632928 1.4999070764872156 1.3783341493656307 1.6498778943225343 1.1785582943360116 1.6032472014305112 1.8406977639967737 1.5162181329828988 1.0 11.509784656579894 -4.757785722910643 24.94269030339761 1.4934764363914497 0.9843373735474334 0.28408605109636287 0.22724771720629366 125.36779823601789 855726.99893827 0.054507181937385484 0.39256967374006047 1.7466837387948847e-05 4.757785722910643 -0.5091390628440162 ASPDQNASTHT(ph)PQSSVK ddPTM_PC-9_AZD4547_30min_R2 2 ASPDQNASTHTPQSSVK 17 0 Q14677-2;Q14677;Q14677-3;H0YD52 Q14677-2 CLINT1 Clathrin interactor 1 1 ASPDQNASTHT(0.932)PQS(0.055)S(0.014)VK;ASPDQNASTHT(1)PQSSVK 141.3 7.9124e-05 27528000.0 17727.300000000003 21787.0 76176.0 147133.0 103254.0 97049.0 52476.0 110181.0 65019.0 97723.0 True False 23364.212649253735 28829.221681993862 75165.85646748572 113213.7600321896 88918.96439377556 90980.51068820499 57146.26234051779 93155.0581575011 68455.77160108062 94301.74751456646 0.24776012391122176 0.3057124861608817 0.7970780865526921 1.2005478479038987 0.9429195824821863 0.9647807499447616 0.6059936729347524 0.9878402109474351 0.7259226197320097 1.0 16.52499688541524 -5.29175787457257 3.859019753609453 0.9129030968222923 0.2601021343297432 0.7344053273447375 0.15208070234561305 0.10627822972974545 3.5001191323373417 0.041324462506184156 0.10315281519434386 5.107896932169967e-06 5.29175787457257 -0.652800962492549 down ASPDQNASTHT(ph)PQSSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASPDQNASTHTPQSSVK 17 0 Q14677-2;Q14677;Q14677-3;H0YD52 Q14677-2 CLINT1 Clathrin interactor 1 1 ASPDQNASTHT(1)PQSSVK;ASPDQNAST(0.001)HT(0.998)PQSSVK 123.6 8.9051e-05 15470200.0 11921.5 15250.3 38826.0 38019.0 50019.0 55494.0 38492.0 31671.0 35700.0 26217.0 True False 13939.574489642144 16764.248998278465 39751.75908842499 35888.918689261045 40218.13601439585 52583.79694839631 34845.759102052965 30839.669808198312 36222.044962235435 30969.934566342206 0.45010022413129425 0.5413072140132215 1.283559673116868 1.1588309498162368 1.2986186951167953 1.6978982256405482 1.1251479730255214 0.9957938316639047 1.169587390785164 1.0 14.91858071442146 -5.239272480097191 6.430274393255311 1.231377538810908 0.4874692802882544 0.6984033851481092 0.189218381939528 0.09747032912993714 16.320556763891602 0.051992388119855494 0.13295501008325875 5.7640470864308875e-06 5.239272480097191 -0.7439082585226536 ASPDQNASTHT(ph)PQSSVK ddPTM_PC-9_Lapatinib_30min_R1 1 ASPDQNASTHTPQSSVK 17 0 Q14677-2;Q14677;Q14677-3;H0YD52 Q14677-2 CLINT1 Clathrin interactor 1 1 ASPDQNASTHT(0.996)PQS(0.003)S(0.001)VK 119.37 0.00020967 8040600.0 12787.0 9719.3 30016.0 10680.0 18941.0 23949.0 13988.0 20139.0 30156.0 12134.0 True False 12604.655035151385 9696.795558002013 27548.20034511066 11465.44282743559 17826.92761943878 22924.757097845722 14712.230196190345 21074.731461034073 26759.51372324207 14231.345732461303 0.8856966355894593 0.6813688417311016 1.9357410650402502 0.8056471287380248 1.2526522757982088 1.610863619563046 1.033790512349943 1.480867084337864 1.88032208803728 1.0 13.796784470770909 -5.222290278208805 24.998724313897075 1.363695609524232 0.7835324038302587 0.30809067118843403 0.3542168788095252 644.8558987868042 411771.89486898907 0.08703649723828548 0.23026855692817952 5.993903156794149e-06 5.222290278208805 -0.5801632056939734 ASPEAAS(ph)TPRDPIDVDLPEEAER ddPTM_PC-9_AZD4547_30min_R2 2 ASPEAASTPRDPIDVDLPEEAER 23 1 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;H3BVD2;H3BT29;P29590-2 P29590;P29590-2 PML Protein PML 1 AS(0.007)PEAAS(0.774)T(0.218)PRDPIDVDLPEEAER;AS(0.003)PEAAS(0.821)T(0.176)PRDPIDVDLPEEAER 67.895 0.00065896 8264400.0 727.32 2806.23 4434.4 4317.200000000001 5536.799999999999 4137.6 2722.65 3755.8 2835.34 3947.5 True False 958.5926308041967 3713.2889686813983 4375.596958614509 3321.9362400750997 4768.110892124816 3878.875217915871 2964.9605755280645 3175.4274096980607 2985.2102839386685 3809.299226525487 0.25164540084674364 0.9747958214530548 1.1486619187449734 0.8720596735859688 1.251702900870267 1.018264774503904 0.7783480370567909 0.833598838228944 0.7836638989007747 1.0 11.895309903009364 -4.760970326513355 24.94260057677779 0.9651851622444334 0.25164457945527374 0.6801667795658148 0.14619282825378602 6.850009167532048 363868.8863823239 0.038889153729071986 0.2228385327059537 1.7339224652216444e-05 4.760970326513355 -0.7135405827891597 ASPEAAS(ph)TPRDPIDVDLPEEAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASPEAASTPRDPIDVDLPEEAER 23 1 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;H3BVD2;H3BT29;P29590-2 P29590;P29590-2 PML Protein PML 1 AS(0.021)PEAAS(0.818)T(0.16)PRDPIDVDLPEEAER;AS(0.004)PEAAS(0.836)T(0.16)PRDPIDVDLPEEAER 73.809 0.00022576 5860200.0 3936.2 2267.7 5289.3 4363.7 8158.2 5934.8 4298.2 4985.2699999999995 5552.6 4643.5199999999995 True False 4602.520916506262 2492.8222692928043 5415.416971781951 4119.216036306281 6559.659274128718 5623.568640381701 3891.0433797267997 4854.411944830186 5633.796270512847 5485.353417915901 0.8390564045470271 0.45445062138583664 0.9872503299595012 0.7509481563853968 1.1958498886697053 1.0251971408103568 0.7093514461653699 0.8849770607259368 1.0270616752080388 1.0 12.421368860231091 -5.280336840771764 24.876588408277176 0.9395796832349139 0.646753492872964 0.3639880211897548 0.15877977007921715 719.8256566786048 947576.5884764406 0.04147116298833825 0.08656009520071759 5.2440057501250974e-06 5.280336840771764 -0.2928261903619499 ASPEAAS(ph)TPRDPIDVDLPEEAER ddPTM_PC-9_Lapatinib_30min_R1 2 ASPEAASTPRDPIDVDLPEEAER 23 1 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;H3BVD2;H3BT29;P29590-2 P29590;P29590-2 PML Protein PML 1 AS(0.009)PEAAS(0.937)T(0.053)PRDPIDVDLPEEAER;AS(0.004)PEAAS(0.848)T(0.148)PRDPIDVDLPEEAER 97.62100000000001 3.6947000000000004e-06 5771400.0 3089.7 4615.700000000001 5182.3 4024.0 4114.5 4664.25 6746.1 4147.2 4207.55 2280.1000000000004 True False 3045.6403114184127 4605.012630237763 4756.231298256497 4319.9383836704865 3872.4931994182393 4464.770900397802 7095.380049079189 4339.894052097946 3733.6514115342634 2674.2122469577243 1.138892514939021 1.7220071576130815 1.7785541531594395 1.6154059531306824 1.4480874522296128 1.66956489915005 2.6532598738754327 1.6228682136338124 1.3961686907169741 1.0 11.384898258500789 -4.760268872391995 24.608444635938994 1.7032965925789973 1.1388916869571437 0.12280994698800696 0.3972229492920943 48.36618358127956 1016300.990156567 0.099207621834543 0.5942470343907996 1.736725286511622e-05 4.760268872391995 -0.5644049056218536 ASPEPQRENAS(ph)PAPGTTAEEAMSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASPEPQRENASPAPGTTAEEAMSR 24 1 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 ASPEPQRENAS(0.986)PAPGT(0.006)T(0.008)AEEAMSR 64.592 0.0021386 41734000.0 22976.0 12293.0 20559.0 31305.0 35741.0 31915.0 31833.0 35016.0 30816.0 25709.0 True False 26865.38300331483 13513.367798393285 21049.204530441675 29551.082342179376 28737.807618915263 30241.321216853466 28817.547789038013 34096.86710251877 31266.625701855657 30369.838187667963 0.8846073804312807 0.4449601514136664 0.6930957089850073 0.973040493649352 0.9462614664369399 0.9957682694909227 0.9488871034136667 1.122721395215211 1.029528886806906 1.0 14.890351601308991 -5.751992236444116 4.086219674294986 1.0056397792837652 0.6428910147567636 0.655432378628694 0.10908952498590062 0.11418540087402206 4.299055946353999 0.029769333986585638 0.05024809434717993 1.7701406015070591e-06 5.751992236444116 -0.36274876452700167 ASPEPQRENAS(ph)PAPGTTAEEAMSR ddPTM_PC-9_Lapatinib_30min_R1 1 ASPEPQRENASPAPGTTAEEAMSR 24 1 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 ASPEPQRENAS(0.997)PAPGT(0.002)TAEEAMSR 80.733 5.5984e-05 15564000.0 39872.0 20651.0 25842.0 21046.0 17777.0 19756.0 15183.0 15935.0 17786.0 10645.0 True False 39303.41796837072 20603.18387829367 23717.370513004727 22593.793047397896 16731.391810926732 18911.081933485337 15969.10144901045 16675.398273577546 15782.753385116848 12484.974066429097 3.1480576378651723 1.6502384200936118 1.8996731900932395 1.8096788128819945 1.3401222719329349 1.5147073460356983 1.2790656483580403 1.3356373977913258 1.2641398613358088 1.0 13.60790520407765 -1.5228787452803376 0.5913504618217228 1.3126156430157634 98.21742718881613 0.8306517766679571 0.23451016728027416 64.72757752128818 0.5168787433662009 0.10510538174167969 8083.150084891864 0.029999999999999995 1.5228787452803376 96.90481154580037 up ASPEPQRENASPAPGT(ph)TAEEAMSR ddPTM_PC-9_Lapatinib_30min_R1 1 ASPEPQRENASPAPGTTAEEAMSR 24 1 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 ASPEPQRENAS(0.007)PAPGT(0.497)T(0.497)AEEAMSR 86.258 1.4522000000000001e-05 16473000.0 23493.0 10558.0 15661.0 11630.0 7361.8 9551.2 6651.6 9016.7 12260.0 3833.6 True False 23157.985511911458 10533.553599681582 14373.413033208235 12485.308996542695 6928.7933978556775 9142.717440934657 6995.9873014712375 9435.64879908168 10879.149696476581 4496.232652049093 5.150530967599628 2.3427510128687548 3.1967680824206814 2.7768378468700226 1.541021991977657 2.03341734035226 1.5559664819130115 2.0985677408800276 2.419614494707823 1.0 12.134500972639417 -1.5228787452803378 0.607122421588733 1.8620171186576746 195.69715567792616 0.7224961999721928 0.5765862013445381 96.31054895048527 0.7276846604746016 0.2529910866052535 24816.521699691457 0.02999999999999998 1.5228787452803378 193.8351385592685 up ASPGLSMPS(ph)SSPPIKK ddPTM_PC-9_AZD4547_30min_R2 1 ASPGLSMPSSSPPIKK 16 1 P57682;P57682-2 P57682 KLF3 Krueppel-like factor 3 1 ASPGLS(0.002)MPS(0.333)S(0.333)S(0.333)PPIKK 53.778999999999996 0.027222000000000003 10209000.0 107210.0 99205.0 149410.0 207660.0 154480.0 154080.0 116360.0 158600.0 134980.0 151550.0 True False 141300.5498934692 131271.0761904899 147428.72577724015 159787.19531501774 133033.11851889954 144445.35324257487 126715.81458081095 134092.0142654329 142114.7672328683 146244.2806282299 0.9661953909341027 0.8976151110086579 1.008099086979143 1.0926047475402851 0.9096637348648549 0.9876991607608361 0.8664668049681711 0.9169043308183142 0.9717629067090883 1.0 17.15802067882082 ASPGLSMPSS(ph)SPPIKK ddPTM_PC-9_AZD4547_30min_R2 1 ASPGLSMPSSSPPIKK 16 1 P57682;P57682-2 P57682 KLF3 Krueppel-like factor 3 1 ASPGLSMPS(0.072)S(0.464)S(0.464)PPIKK 110.77 0.00024479 8448400.0 24204.0 24003.0 41332.0 48120.0 38911.0 36805.0 28646.0 36446.0 31329.0 38699.0 True False 31900.36852552491 31761.500345751996 40783.910674150946 37026.67744658894 33508.879302750465 34503.577531756026 31195.438505344802 30814.108145762682 32984.98698057888 37344.15978905883 0.8542264360937945 0.8505078310814626 1.0921094731953214 0.991498474078324 0.8972990553818262 0.9239350336612729 0.8353498560833736 0.825138611226451 0.8832702935853142 1.0 15.188595018757626 -6.779534390265211 2.1741930808703627 0.8739848714062532 0.9477533720797383 0.07059614397840308 0.07956556566846333 0.6628209586782103 6.439355046644251 0.03314003669347129 0.03016989641645513 1.661367114690718e-07 6.779534390265211 0.07376850067348506 ASPGLSMPSS(ph)SPPIKK ddPTM_PC-9_Lapatinib_30min_R1 1 ASPGLSMPSSSPPIKK 16 1 P57682;P57682-2 P57682 KLF3 Krueppel-like factor 3 1 ASPGLSMPS(0.015)S(0.771)S(0.213)PPIKK 69.024 0.010184 5965400.0 32168.0 19742.0 29222.0 24633.0 22589.0 32049.0 25359.0 23049.0 22256.0 19521.0 True False 31709.27842111128 19696.288611944867 26819.47996018204 26444.59299327911 21260.359431682722 30678.33897986798 26671.964937460052 24119.940684511363 19749.294913930087 22895.178839902535 1.384976227652226 0.8602810552244943 1.1714029467828437 1.1550288896276508 0.9285954733242533 1.3399475581470748 1.1649598862698203 1.05349431219442 0.862596228316431 1.0 14.48275621385258 -8.035761240550693 4.638565874796914 0.9343429989315476 1.132646858529434 0.2311285571106555 0.15335682715407387 0.31033831390418637 15.635926766015235 0.10088211679532953 0.03841626319747538 9.209557408684133e-09 8.035761240550693 0.19830385959788643 ASPGLSMPSSS(ph)PPIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASPGLSMPSSSPPIK 15 0 P57682;P57682-2 P57682 KLF3 Krueppel-like factor 3 1 ASPGLSMPS(0.141)S(0.141)S(0.718)PPIK 86.944 0.0229 0.0 14224.0 15114.0 16279.0 20453.0 19033.0 15121.0 18722.0 17979.0 16712.0 14803.0 True False 16631.8422631942 16614.418035053786 16667.153098451297 19307.084719520677 15303.620279533705 14328.028141000828 16948.516624457945 17507.070300325126 16956.3813840022 17486.666719516477 0.9511156431335066 0.9501192137727887 0.953134943656784 1.1041032021255641 0.8751593728525561 0.8193687436731231 0.9692251185608796 1.00116680789632 0.9696748760630043 1.0 14.093967690791436 -7.517214004680043 24.662390261112538 0.9882917169946538 0.9429214199319895 0.0918450856048082 0.06834415407845752 645.0420633256996 2808344.1273045614 0.03385039084208109 0.02035407588841651 3.039386956177423e-08 7.517214004680043 -0.04537029706266427 ASPGT(ph)PLSPGSLR ddPTM_PC-9_Lapatinib_30min_R1 1 ASPGTPLSPGSLR 13 0 E1P5H9;Q96BD0-2;Q96BD0-3;Q96BD0-4;Q96BD0 E1P5H9 SLCO4A1 Solute carrier organic anion transporter family member 4A1 1 ASPGT(0.735)PLS(0.265)PGSLR 159.58 0.00066031 5523600.0 31389.0 38166.0 28683.0 25729.0 26821.0 18184.0 18569.0 13986.0 29972.0 13350.0 True False 30941.387103962374 38077.62897191207 26324.794459581866 27621.196489427923 25243.441512114845 17406.31270897436 19530.411961185197 14635.840618403234 26596.237740847995 15657.529712243151 1.9761346567823057 2.4319052667763987 1.6812865722360801 1.7640839262038874 1.612223765564765 1.1116895850667796 1.2473495066028013 0.9347477467635892 1.698622849813371 1.0 13.934568996200271 -6.01680282617813 0.9089737388854205 1.183571246262967 2.2139458311202285 0.6803619090851842 0.2536562936227773 0.3558305454762283 0.5967510113096484 0.11092081574642587 0.24533789351187285 9.62048958617208e-07 6.01680282617813 1.0303745848572614 ASPGTPLS(ph)PGSLR ddPTM_PC-9_AZD4547_30min_R2 1 ASPGTPLSPGSLR 13 0 E1P5H9;Q96BD0-2;Q96BD0-3;Q96BD0-4;Q96BD0 E1P5H9 SLCO4A1 Solute carrier organic anion transporter family member 4A1 1 ASPGT(0.028)PLS(0.698)PGS(0.274)LR 115.37 0.0002904 6710100.0 10673.0 16508.0 24484.0 25074.0 23080.0 13953.0 25886.0 29560.0 21954.0 13862.0 True False 14066.791987808932 21843.888168465346 24159.326162438607 19293.5766894383 19875.740389799324 13080.516704268222 28189.80385217325 24992.181221224408 23114.443620020702 13376.695599264422 1.0515894514772737 1.6329808812922775 1.8060757967585894 1.4423275573751746 1.4858482980574277 0.9778585905017914 2.1073817254033496 1.8683374407203164 1.7279636400855047 1.0 13.707434155370086 -7.272597885334695 24.996940226671683 1.7482821060605314 1.4344215434109682 0.11129898775566971 0.35199076559537323 1454.803918224822 3258994.851905121 0.1438340270264528 0.0979530145494467 5.338289406758849e-08 7.272597885334695 -0.3138605626495632 ASPGTPLS(ph)PGSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ASPGTPLSPGSLR 13 0 E1P5H9;Q96BD0-2;Q96BD0-3;Q96BD0-4;Q96BD0 E1P5H9 SLCO4A1 Solute carrier organic anion transporter family member 4A1 1 ASPGT(0.392)PLS(0.606)PGS(0.002)LR;ASPGT(0.028)PLS(0.938)PGS(0.033)LR;ASPGT(0.001)PLS(0.969)PGS(0.029)LR;ASPGT(0.288)PLS(0.64)PGS(0.072)LR 147.7 0.00011129 19560700.0 63514.0 77535.0 81801.0 77676.0 116922.0 69900.0 72038.0 89100.0 65930.0 56947.0 True False 74265.66574131857 85232.16238903636 83751.44607201988 73324.06554898983 94011.97343159965 66234.32094808268 65214.039130044934 86761.21940925371 66894.1015226943 67271.04030779605 1.1039767692237088 1.2669963478944266 1.2449851479747953 1.0899796586093868 1.397510325415684 0.9845889203590444 0.9694221886812009 1.2897261438544891 0.9943967153863373 1.0 16.037697948337023 -6.789224317401807 24.999025525943907 1.0608468966526978 1.2173505275077796 0.3465390566615407 0.118084909294702 277.2219296094365 249423.76508238327 0.04083906069581871 0.03602410463753156 1.6247093605129044e-07 6.789224317401807 0.1565036308550818 ASPGTPLS(ph)PGSLR ddPTM_PC-9_Lapatinib_30min_R1 2 ASPGTPLSPGSLR 13 0 E1P5H9;Q96BD0-2;Q96BD0-3;Q96BD0-4;Q96BD0 E1P5H9 SLCO4A1 Solute carrier organic anion transporter family member 4A1 1 ASPGT(0.003)PLS(0.911)PGS(0.086)LR;ASPGT(0.001)PLS(0.913)PGS(0.086)LR 111.72 0.00053497 11124600.0 57901.0 70850.0 41183.0 32219.0 39947.0 29939.0 28902.0 27041.0 48341.0 17033.3 True False 57075.32112225704 70685.9511780111 37797.092710977246 34588.49273943328 37597.39599882376 28658.578761217726 30398.404141427895 28297.42357802385 42896.32752670264 19977.48320955442 2.8569825599933543 3.5382810955989132 1.8919847067072209 1.7313738861205001 1.8819886171068063 1.4345440043974855 1.5216333220037233 1.416465892184574 2.1472338170299183 1.0 14.286087221448454 -5.36189645496645 4.558044830908303 1.6246345641609026 3.1916959919022347 0.785625918609728 0.3298621953606748 0.08666526296568614 2.9518180083321623 0.08332833551965672 0.18357070690893712 4.346138329934445e-06 5.36189645496645 1.5670614277413322 ASPGTPLSPGS(ph)LR ddPTM_PC-9_AZD4547_30min_R2 1 ASPGTPLSPGSLR 13 0 E1P5H9;Q96BD0-2;Q96BD0-3;Q96BD0-4;Q96BD0 E1P5H9 SLCO4A1 Solute carrier organic anion transporter family member 4A1 1 ASPGT(0.061)PLS(0.099)PGS(0.84)LR 130.19 8.3594e-05 6523000.0 16676.0 18582.0 25157.0 33829.0 27136.0 19346.0 25348.0 42092.0 23817.0 17445.0 True False 21978.62111765217 24588.26810918481 24823.401742708207 26030.24670283992 23368.634801455548 18136.29156172671 27603.922894417356 35587.64857793568 25075.91799663083 16834.255859844754 1.305589109529838 1.460609148031065 1.474576717223373 1.5462665483735833 1.3881596546953667 1.077344416808333 1.63974713965598 2.11400188248439 1.4895768607417423 1.0 14.039112329343503 -7.475747408639239 24.947307715275475 1.656448907056915 1.389347441781551 0.052717311556072954 0.2845091906393891 702.690215029331 371944.90711000096 0.11536079900713603 0.0777736019833796 3.3438946877565906e-08 7.475747408639239 -0.26710146527536405 ASPITNDGEDEFVPS(ph)DGLDKDEYTFSPGK ddPTM_PC-9_AZD4547_30min_R2 3 ASPITNDGEDEFVPSDGLDKDEYTFSPGK 29 1 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 ASPIT(0.001)NDGEDEFVPS(0.972)DGLDKDEY(0.017)T(0.006)FS(0.004)PGK;ASPITNDGEDEFVPS(0.997)DGLDKDEY(0.001)T(0.002)FSPGK;ASPITNDGEDEFVPS(0.766)DGLDKDEY(0.212)T(0.022)FSPGK 116.92 1.5092e-07 0.0 24924.199999999997 23655.300000000003 28068.3 30909.4 32416.1 28894.0 28556.9 28420.3 26247.1 30512.7 True False 32849.57714443428 31301.413120396057 27696.09600249856 23783.71537546958 27915.68405761583 27087.253612350458 31098.408777954373 24028.595668523827 27634.46812148333 29444.459660343055 1.1156454396980282 1.0630663113357797 0.9406216423051139 0.8077484066553414 0.9480793459835081 0.9199439869101292 1.056171827796824 0.8160650915556272 0.9385286210126147 1.0 14.84570857820642 -5.205526060489207 3.362171248876825 0.9215406467637749 1.103375396196811 0.4605276728458497 0.07051644194063164 0.2078020870905569 4.668971369937509 0.018458576377215687 0.056983264350269056 6.229797634760181e-06 5.205526060489207 0.181834749433036 ASPITNDGEDEFVPS(ph)DGLDKDEYTFSPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASPITNDGEDEFVPSDGLDKDEYTFSPGK 29 1 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 ASPITNDGEDEFVPS(0.433)DGLDKDEY(0.178)T(0.387)FS(0.002)PGK;ASPITNDGEDEFVPS(0.709)DGLDKDEY(0.127)T(0.102)FS(0.061)PGK 130.14 2.0618000000000004e-11 0.0 17245.4 16743.7 15347.6 21216.0 23337.0 19366.7 24368.0 19603.8 15485.0 15716.900000000001 True False 20164.705607824068 18405.903880741695 15713.544990097127 20027.33630320005 18764.282376056235 18351.07615887315 22059.686630957767 19089.22102194304 15711.438830258152 18566.249555088063 1.0860947197759683 0.9913635937150039 0.8463499827185531 1.0786958477411814 1.0106662802511939 0.9884105082409633 1.1881606226127845 1.0281678572348856 0.8462365424767463 1.0 14.180394794998687 -4.756723781283389 24.25090299815666 1.002331397348236 1.0860949063246783 0.07063891111632847 0.094929631941006 322.4686769444166 1658060.298045931 0.024231118721424427 0.18823395062680426 1.7509599750367992e-05 4.756723781283389 0.08376350897644236 ASPITNDGEDEFVPS(ph)DGLDKDEYTFSPGK ddPTM_PC-9_Lapatinib_30min_R1 2 ASPITNDGEDEFVPSDGLDKDEYTFSPGK 29 1 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 ASPITNDGEDEFVPS(0.999)DGLDKDEYT(0.001)FSPGK;ASPITNDGEDEFVPS(0.855)DGLDKDEY(0.043)T(0.099)FS(0.002)PGK 137.86 1.6967e-16 0.0 23521.0 20989.0 17254.7 18589.2 16052.6 18544.6 16668.2 19063.5 20125.9 16003.4 True False 23185.586226776886 20940.401260060327 15836.085171068142 19956.31177975333 15108.417628625875 17751.490687574016 17531.197837871026 19949.259804728285 17859.1092068775 18769.5663668099 1.235275539864139 1.1156571681426322 0.8437107635619641 1.0632271087009204 0.8049422844068465 0.9457592328272356 0.9340225285583224 1.0628513954379057 0.9514929038775048 1.0 14.196107699527534 -5.038246776033993 4.505440100593875 0.9513370229397303 1.2154790710652978 0.5860259070300277 0.07843659417689446 0.12194074514977811 5.714445187485536 0.019561563696779805 0.06520948271086978 9.157000206192724e-06 5.038246776033993 0.2641420481255675 ASPITNDGEDEFVPSDGLDKDEYT(ph)FSPGK ddPTM_PC-9_AZD4547_30min_R2 1 ASPITNDGEDEFVPSDGLDKDEYTFSPGK 29 1 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 ASPITNDGEDEFVPS(0.002)DGLDKDEY(0.045)T(0.898)FS(0.055)PGK 94.072 3.8704e-05 0.0 5272.4 6784.8 6926.6 7805.1 11165.0 7168.8 5779.5 6217.0 7906.1 6795.9 True False 6948.913527267284 8977.853916004588 6834.748758239959 6005.754782592919 9614.932471928485 6720.533802734749 6293.864303624948 5256.305502447637 8324.000305376954 6557.9776095109755 1.059612267841436 1.3689973419525079 1.0422037349330966 0.9157937309640745 1.4661429246089581 1.024787549287759 0.9597264093273227 0.8015131821774544 1.2692937977258008 1.0 12.679035260698852 -6.9746799199194855 24.998812612220004 0.9912588696000391 1.1688087661691762 0.15780250785122685 0.18298358818252838 393.6179162243882 388622.43452843506 0.06347551541763628 0.055978288607991186 1.060034695240001e-07 6.9746799199194855 0.1775498965691371 ASPITNDGEDEFVPSDGLDKDEYT(ph)FSPGK ddPTM_PC-9_Lapatinib_30min_R1 2 ASPITNDGEDEFVPSDGLDKDEYTFSPGK 29 1 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 ASPIT(0.005)NDGEDEFVPS(0.094)DGLDKDEY(0.097)T(0.66)FS(0.144)PGK;ASPITNDGEDEFVPSDGLDKDEY(0.05)T(0.475)FS(0.475)PGK 112.26 9.661e-06 0.0 16485.6 15194.4 13738.5 12021.400000000001 15596.3 12094.5 13419.3 14856.4 16623.9 14346.2 True False 16250.512320911213 15159.218300341157 12608.973562143632 12905.493858214812 14678.956297505569 11577.246428656528 14114.08569286082 15546.682579954651 14751.541324572363 16825.921554890105 0.9658022158190996 0.9009443108889001 0.7493778882190911 0.7670007147076053 0.8724013272984406 0.6880601690010757 0.8388298760824101 0.9239721300992474 0.876715208522123 1.0 14.038397902884908 -8.395263577470127 1.1481544076612646 0.9908986935281727 0.8225982300857394 0.29358618128917036 0.07878401219486164 0.6120883571219474 1.729834773238378 0.07838372885920282 0.025238343824905096 4.024726956631786e-09 8.395263577470127 -0.16830046344243332 ASPITNDGEDEFVPSDGLDKDEYTFS(ph)PGK ddPTM_PC-9_Lapatinib_30min_R1 1 ASPITNDGEDEFVPSDGLDKDEYTFSPGK 29 1 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 ASPITNDGEDEFVPS(0.002)DGLDKDEY(0.015)T(0.261)FS(0.722)PGK 82.62700000000001 4.3774e-05 0.0 8145.2 7407.6 5646.4 5630.4 5552.3 6030.6 6864.2 7107.9 6628.2 5661.2 True False 8029.047954353253 7390.448157321584 5182.174787734305 6044.478398463793 5225.724630241797 5772.685296015221 7219.59468921145 7438.158982664681 5881.662317959718 6639.730876925165 1.2092429803527633 1.11306441395168 0.7804796434963568 0.9103499088298845 0.7870386205565324 0.8694155535846854 1.087332427026744 1.120250070453046 0.8858284209078507 1.0 12.696909051777372 -10.291442600798021 15.307046215750344 1.0000069366033222 0.9693216692758105 0.002218634084171889 0.14291556142957815 0.0 0.0 0.14896525181977843 0.036129380458804705 5.111606329088367e-11 10.291442600798021 -0.030685267327511645 ASPLS(ph)SDSPVKTPIK ddPTM_PC-9_Lapatinib_30min_R1 1 ASPLSSDSPVKTPIK 15 1 Q9Y426-2;Q9Y426-3;Q9Y426 Q9Y426-2 C2CD2 C2 domain-containing protein 2 1 AS(0.002)PLS(0.486)S(0.092)DS(0.415)PVKT(0.005)PIK 52.861999999999995 0.039361 4433200.0 34431.0 34599.0 21544.0 15487.0 11669.0 13248.0 13598.0 12299.0 18194.0 7952.1 True False 33940.00762612792 34518.88814125624 19772.73548224496 16625.96564311751 10982.652362136692 12681.413922596354 14302.037904474997 12870.456439706935 16144.800128686378 9326.6098894928 3.63905084787176 3.701118471798057 2.1200345802519935 1.7826376186108137 1.177561031528676 1.3597024077186952 1.53346586529661 1.37997156439518 1.731047006359174 1.0 13.187137058729476 -5.402825776993409 1.9163449981300673 1.410384323361246 3.8117547953528077 0.9401229358511972 0.22386379531710854 0.07529630125893565 0.5176234256966833 0.06262458184581164 0.2007338673574032 3.955252584631107e-06 5.402825776993409 2.4013704719915614 ASPS(ph)KPASAPASR ddPTM_PC-9_AZD4547_30min_R2 1 ASPSKPASAPASR 13 1 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 AS(0.118)PS(0.882)KPASAPASR 85.973 0.0036924999999999996 382570000.0 337970.0 357380.0 434710.0 485980.0 511170.0 432250.0 428500.0 466260.0 337600.0 398300.0 True False 445437.42978729313 472896.0960531953 428945.46136553126 373944.8193161529 440202.8689364696 405221.3391686329 466635.6698855079 394210.230588908 355444.84677593986 384355.6382330851 1.1589199831567611 1.230360762306332 1.1160118876814955 0.9729135782558268 1.145300927443445 1.0542874849747728 1.2140726542497748 1.0256392553550802 0.9247811438644414 1.0 18.552082306400678 -1.5228787465354607 0.1479089301713987 0.962486986085212 1.7929061787465217 0.3336183849639043 0.08071730746812364 89.79919439369107 0.876841483791887 0.3142361927068701 15.9430477630693 0.02999999991329916 1.5228787465354607 0.8304191926613097 ASPS(ph)KPASAPASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASPSKPASAPASR 13 1 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 AS(0.247)PS(0.722)KPAS(0.019)APAS(0.012)R 52.79 0.042741 276990000.0 19630.0 21401.0 22744.0 25650.0 24051.0 27329.0 20848.0 19540.0 23672.0 17356.0 True False 22952.97128982721 23525.549845718284 23286.30321710032 24212.913658422003 19338.379201548105 25895.819130045085 18873.126513550866 19027.095704341355 24018.15821697584 20502.505409979596 1.119520313778571 1.1474475619095421 1.135778420805377 1.180973406627483 0.9432202950247801 1.2630563246889959 0.9205278153158964 0.928037589741589 1.1714743021252905 1.0 14.32351259765554 -7.278654304911799 24.990210279796262 0.9990130672356685 1.1262458582238868 0.28298837429155 0.09835522573429117 1101.6112500168151 1599158.3912876232 0.03972846178789691 0.02685897943646152 5.2643613880180666e-08 7.278654304911799 0.12723279098821827 ASPS(ph)KPASAPASR ddPTM_PC-9_Lapatinib_30min_R1 1 ASPSKPASAPASR 13 1 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 AS(0.446)PS(0.553)KPAS(0.001)APASR 69.352 0.014491 455660000.0 219580.0 157210.0 244300.0 160500.0 206990.0 175970.0 159970.0 144680.0 206390.0 140550.0 True False 216448.74893396013 156845.98990395357 224214.59702527098 172303.70541230464 194815.25515799748 168444.1733061053 168252.46386077837 151402.3609803077 183144.1848169497 164843.8802288971 1.3130529846385934 0.9514820306714578 1.3601633055102413 1.0452538800533515 1.1818167279700227 1.0218406232139705 1.0206776474027923 0.9184590945692075 1.1110159780432334 1.0 17.33074080289306 -6.793370723229533 6.845843297356703 1.0088631542750046 1.1618617132241158 0.302003716815368 0.11807039247183598 0.2331310349278882 34.039763341716174 0.0385328832962317 0.03459459800633407 1.6092713396288408e-07 6.793370723229533 0.15299855894911119 ASPS(ph)PQPSSQPLQIHR ddPTM_PC-9_AZD4547_30min_R2 5 ASPSPQPSSQPLQIHR 16 0 B5MBZ0;Q9HC35 B5MBZ0 EML4 Echinoderm microtubule-associated protein-like 4 1 ASPS(1)PQPSSQPLQIHR;ASPS(1)PQPSSQPLQIHR;AS(0.058)PS(0.941)PQPSSQPLQIHR;AS(0.004)PS(0.98)PQPS(0.008)S(0.008)QPLQIHR;AS(0.208)PS(0.792)PQPSSQPLQIHR 272.24 1.7406e-70 150410300.0 56601.8 59013.11 118503.1 126817.1 138378.4 109756.9 95700.4 120078.5 84325.5 103180.8 True False 74599.99500942224 78087.94374323625 116931.67146545001 97581.3768996635 119166.94774505193 102893.78369230228 104217.5502037595 101523.12695442476 88782.77377607979 99568.47159779139 0.7492331037355906 0.7842637582976455 1.174384517398214 0.9800429326046624 1.1968341567642913 1.033397239519188 1.0466922764943922 1.0196312680637425 0.8916755711056747 1.0 16.603401364108727 -5.188690683761626 7.532607609447869 1.0464034443918409 0.7629028217482596 0.6322662831221812 0.0842145589581731 0.17526346170379664 16.041808387411447 0.021100179742496495 0.05652640937661812 6.476036923422604e-06 5.188690683761626 -0.2835006226435812 ASPS(ph)PQPSSQPLQIHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 ASPSPQPSSQPLQIHR 16 0 B5MBZ0;Q9HC35 B5MBZ0 EML4 Echinoderm microtubule-associated protein-like 4 1 AS(0.02)PS(0.98)PQPSSQPLQIHR;AS(0.141)PS(0.859)PQPSSQPLQIHR;AS(0.018)PS(0.982)PQPSSQPLQIHR;AS(0.002)PS(0.997)PQPSSQPLQIHR;AS(0.183)PS(0.817)PQPSSQPLQIHR;AS(0.022)PS(0.971)PQPS(0.004)S(0.004)QPLQIHR;AS(0.158)PS(0.823)PQPS(0.018)S(0.001)QPLQIHR 164.93 1.6899999999999997e-05 335112000.0 118193.3 144413.4 172751.0 189811.0 202431.0 166310.1 206760.0 154695.2 159711.3 137542.5 True False 138201.0912659163 158749.80795708875 176870.03900181595 179176.50504556453 162766.0987130923 157588.50558380148 187174.1959872302 150634.6149131127 162046.77561840572 162477.86646416897 0.8505841089216518 0.9770549762363948 1.0885792806789525 1.1027748513984708 1.0017739785436368 0.969907526564883 1.1519981155618355 0.9271085237097937 0.9973467718702577 1.0 17.309883674933317 -4.836016607360938 3.3542752470324295 1.0312973279984499 0.8373249568600883 0.4177235877334349 0.06390789002852205 0.2718418040480968 5.0236503990094326 0.0164336943040804 0.12595684252530082 1.458758476486334e-05 4.836016607360938 -0.19397237113836152 ASPS(ph)PQPSSQPLQIHR ddPTM_PC-9_Lapatinib_30min_R1 5 ASPSPQPSSQPLQIHR 16 0 B5MBZ0;Q9HC35 B5MBZ0 EML4 Echinoderm microtubule-associated protein-like 4 1 ASPS(0.791)PQPS(0.105)S(0.105)QPLQIHR;AS(0.079)PS(0.921)PQPSSQPLQIHR;AS(0.426)PS(0.574)PQPSSQPLQIHR;ASPS(0.995)PQPS(0.001)S(0.004)QPLQIHR;AS(0.024)PS(0.976)PQPSSQPLQIHR 295.22 1.1859999999999997e-111 129131100.0 38542.200000000004 41760.8 37650.200000000004 34836.1 37980.1 42882.9 27599.7 30908.1 30610.4 22454.299999999996 True False 37992.58116022616 41664.105433375895 34554.74588997488 37398.06300382292 35746.18518974958 41048.89833192235 29028.677419630723 32344.203161566475 27162.734410197954 26335.49583652594 1.4426377766365217 1.5820513003438492 1.312097790163847 1.4200629916355623 1.3573386053423573 1.5586909237148174 1.102264320361475 1.2281600225922755 1.0314115435231213 1.0 14.684721001910615 -7.273643028628829 24.834153557505548 1.1094722715333278 1.4404631282345293 0.769663470608996 0.09489450511685138 353.52630251646013 719415.2457714428 0.038944643018365456 0.02647951620100044 5.3254580915179786e-08 7.273643028628829 0.33099085670120143 ASPS(ph)TAGETPSGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASPSTAGETPSGVK 14 0 A0A087WW69;F8W8L6;A0A087WTA5;E7ERK9;Q9UI10-3;Q9UI10;Q9UI10-2 A0A087WW69 EIF2B4 Translation initiation factor eIF-2B subunit delta 1 AS(0.143)PS(0.652)T(0.204)AGETPSGVK;AS(0.345)PS(0.596)T(0.059)AGETPSGVK 185.66 5.6713e-06 10198300.0 39610.0 65427.0 45803.0 37274.0 51054.0 30389.0 44946.0 29673.8 27791.7 26583.6 True False 46315.19066683934 71922.1601680206 46895.117228844814 35185.65862393847 41050.33519420551 28795.347343222966 40688.38949913935 28894.89419198999 28198.101035769167 31402.99624433819 1.4748653378955758 2.290296110868332 1.4933325745087074 1.120455460688159 1.307210779341054 0.9169617803082925 1.2956849461928424 0.9201317596310449 0.8979430120733511 1.0 14.93861459664797 -5.587149606835791 3.309801707364585 1.0743057791625947 1.8910705185168817 0.6683961253645305 0.2314604829059669 0.1268225031531005 2.7988542443830386 0.06153176792533657 0.12029346483878352 2.587321474727064e-06 5.587149606835791 0.816764739354287 ASPS(ph)TAGETPSGVK ddPTM_PC-9_Lapatinib_30min_R1 1 ASPSTAGETPSGVK 14 0 A0A087WW69;F8W8L6;A0A087WTA5;E7ERK9;Q9UI10-3;Q9UI10;Q9UI10-2 A0A087WW69 EIF2B4 Translation initiation factor eIF-2B subunit delta 1 AS(0.141)PS(0.674)T(0.183)AGET(0.001)PSGVK 72.681 0.022226 9010200.0 13621.0 30766.0 26418.0 28362.0 39579.0 36732.0 39560.0 41257.0 30526.0 31539.0 True False 13426.762042214526 30694.7632172574 24246.01401642904 30447.836092858448 37251.041035307935 35161.05798647416 41608.223231433396 43173.950836083364 27087.840426969364 36990.47412692412 0.36297891170964036 0.8298018325457396 0.6554664299039407 0.8231264078525691 1.0070441624373276 0.9505435876768503 1.1248361696761322 1.1671640295266856 0.7322923283984899 1.0 15.174866171932916 -4.636122245597154 0.5760410790722926 1.0242179683223018 4.272695849596068e-16 0.6234542917482722 0.14007369141413764 2.9810864482897035 0.6668800926120199 0.07346907606864808 2.118214498356086 2.3114140797070125e-05 4.636122245597154 -1.0242179683223014 ASPTPLAS(ph)PGK ddPTM_PC-9_AZD4547_30min_R2 4 ASPTPLASPGK 11 0 A0A1B0GTL5 A0A1B0GTL5 1 ASPT(0.01)PLAS(0.99)PGK;ASPT(0.008)PLAS(0.992)PGK;AS(0.004)PT(0.006)PLAS(0.99)PGK;AS(0.002)PT(0.018)PLAS(0.98)PGK 120.59 0.00085157 48201900.0 261498.0 285261.0 321291.0 395648.0 334826.0 336233.0 336435.0 385531.0 321976.0 337163.0 True False 344648.92450370657 377466.03966710664 317030.47141218965 304437.4663006657 288341.18941745866 315208.2973572866 366377.0632390455 325956.0425710378 338994.994032968 325359.02599442936 1.0592880386530523 1.1601523532762525 0.9744019562488415 0.9356970053932917 0.8862246514789957 0.9688014536983629 1.126070076338741 1.0018349470243946 1.041910526369636 1.0 18.31167305145624 -5.271872130704308 24.877097516726042 0.9901232103176387 1.109720196547037 0.3515618576744334 0.06398741976882806 681.2256400401968 1624398.0203030652 0.01843035152184636 0.039061889385414786 5.34721774318783e-06 5.271872130704308 0.11959698622939818 ASPTPLAS(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASPTPLASPGK 11 0 A0A1B0GTL5 A0A1B0GTL5 1 ASPT(0.001)PLAS(0.999)PGK;ASPT(0.005)PLAS(0.995)PGK 96.756 0.0056729 21029000.0 128231.0 145361.0 135548.0 151504.0 168040.0 156308.0 180875.0 179724.0 162894.0 146272.0 True False 149937.9756223044 159791.47942261823 138779.9783886526 143015.72206259554 135113.76828523306 148110.9333154921 163741.21057840125 175006.43543331817 165276.01658482876 172789.95571148494 0.8677470574311766 0.9247729635941868 0.8031715606223067 0.8276853910501327 0.7819538336524521 0.857173281315029 0.9476315327715416 1.0128275958675177 0.9565140282852868 1.0 17.39865983044283 -7.334774959173933 3.1025371729988587 0.9874003005766936 0.8409302754932114 0.7539194372519915 0.03848220579309434 0.1397797996089186 2.636401409326021 0.01913431377516097 0.01239755936132741 4.6262067807299114e-08 7.334774959173933 -0.14647002508348217 ASPTPLAS(ph)PGK ddPTM_PC-9_Lapatinib_30min_R1 3 ASPTPLASPGK 11 0 A0A1B0GTL5 A0A1B0GTL5 1 ASPTPLAS(1)PGK;ASPT(0.002)PLAS(0.998)PGK;ASPT(0.013)PLAS(0.987)PGK 145.81 0.00021334 41298000.0 291211.0 320570.0 307156.0 260544.0 361733.0 330745.0 322924.0 311843.0 319760.0 290932.0 True False 287058.27773844294 319827.7398607625 281902.81933644763 279705.27490930515 340456.5761344411 316599.80735425197 339643.42464073264 326332.3642188409 283745.26157792436 341219.20855747804 0.8412723274050038 0.937308720727801 0.8261633936969917 0.8197231219536959 0.9977649780437009 0.9278487242634849 0.9953819014955017 0.956371611077899 0.8315629790522996 1.0 18.380339338298732 -6.258593676180465 24.973293455541782 0.9503196409059792 0.8597767718166295 0.41660946889674444 0.055210773317545994 269.79117477456083 2367629.049148666 0.016637028920893256 0.020541833632372036 5.513232705723852e-07 6.258593676180465 -0.09054286908934972 ASPVPSDPEKPGT(ph)PGEGMLSSDLDR ddPTM_PC-9_AZD4547_30min_R2 1 ASPVPSDPEKPGTPGEGMLSSDLDR 25 1 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 ASPVPS(0.002)DPEKPGT(0.833)PGEGMLS(0.086)S(0.079)DLDR 46.878 0.025960000000000004 4207500.0 29523.0 27609.0 33017.0 40165.0 39502.0 35107.0 33846.0 40226.0 35810.0 39980.0 True False 38910.699883451955 36533.06932657863 32579.17300707544 30905.57979306411 34017.82915415306 32911.75374018092 36858.22843160999 34009.99600152142 37702.84349243605 38580.31236896489 1.0085636298464196 0.9469355503706828 0.8444507316452693 0.8010712691358467 0.881740635711337 0.8530712096218296 0.9553636600739346 0.8815376007395946 0.977256045307847 1.0 15.235577203893754 -8.354984749573752 3.773343739452431 0.9990934616207159 0.8931870296750676 0.29222036921373085 0.057382409207158265 0.3086124579429848 7.603475319789972 0.05874068704683154 0.015699834719875697 4.41585953550279e-09 8.354984749573752 -0.1059064319456483 ASPVPSDPEKPGT(ph)PGEGMLSSDLDR ddPTM_PC-9_Lapatinib_30min_R1 2 ASPVPSDPEKPGTPGEGMLSSDLDR 25 1 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 ASPVPS(0.002)DPEKPGT(0.965)PGEGMLS(0.016)S(0.016)DLDR;ASPVPS(0.001)DPEKPGT(0.433)PGEGMLS(0.283)S(0.283)DLDR 62.284 0.017612 4540300.0 26869.0 26008.0 28635.0 25831.0 29988.0 32570.0 24668.9 24430.9 32385.0 24894.0 True False 26485.843132828864 25947.78007392674 26280.740834296503 27730.69790968996 28224.164798676422 31177.05702437829 25946.13493614528 25566.048803385347 28737.46027083151 29196.894730830056 0.9071458926370518 0.8887171157461324 0.9001210942664296 0.9497824397198006 0.9666837880835837 1.0678209895882287 0.8886607694190102 0.8756427366362777 0.9842642697371028 1.0 14.8335273173308 -5.789017045306425 4.1305741779549665 0.9589492186194566 0.8967732646179594 0.2421126334658188 0.05128174003021625 0.3444957340988202 12.956608717391106 0.01564906806749032 0.025437460859485887 1.6254849570284954e-06 5.789017045306425 -0.062175954001497225 ASPVT(ph)SPAAAFPTASPANK ddPTM_PC-9_Lapatinib_30min_R1 1 ASPVTSPAAAFPTASPANK 19 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;H0YHQ7 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 ASPVT(0.504)S(0.342)PAAAFPT(0.147)AS(0.007)PANK 205.68 2.7314999999999996e-72 0.0 12452.0 13676.0 13111.0 11793.0 19972.0 13655.0 15950.0 16192.0 13840.0 20167.0 True False 12274.43219658286 13644.334062250937 12033.064189923582 12660.296560294742 18797.28622646277 13071.007481359708 16775.812956050624 16944.339431802167 12281.193458338987 23652.83907916162 0.5189411789215932 0.5768581951868825 0.508736568563764 0.5352548384539845 0.7947158547670229 0.5526189662734987 0.7092515574940126 0.7163765573803905 0.5192270330524016 1.0 14.529725741955467 -14.522878745280327 0.16357192348283647 2.444357160627407 0.5108940927788911 0.6215792236482458 0.09392599758004383 87.96046891678077 0.8138341669039123 41.38690379634681 0.3731709354077444 3.0000000000000748e-15 14.522878745280327 -1.9334630678485158 ASPVTS(ph)PAAAFPTASPANK ddPTM_PC-9_AZD4547_30min_R2 1 ASPVTSPAAAFPTASPANK 19 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;H0YHQ7 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 ASPVT(0.031)S(0.786)PAAAFPT(0.177)AS(0.007)PANK 249.86 7.851399999999996e-137 0.0 14057.0 16024.0 16504.0 12289.0 18054.0 19823.0 17912.0 25253.0 19127.0 14761.0 True False 18526.8335962363 21203.4446336012 16285.146176477963 9455.960913157349 15547.513734724305 18583.464676321146 19506.13329985813 21350.72910621043 20138.014171455576 14244.221882898733 1.3006560659153428 1.4885646129296497 1.143280855237836 0.6638453817200044 1.0914961773651022 1.3046317888821994 1.3694067292841543 1.4989045580540694 1.4137672339710452 1.0 13.798089193465033 -6.875871740420325 4.731008885952395 1.3585416812500233 1.131804747705009 0.1236660719387237 0.2298762865488935 0.4253337310306235 15.763519728909838 0.09039273164855183 0.07971515260268494 1.330847397239802e-07 6.875871740420325 -0.22673693354501423 ASPVTT(ph)SPTAATTQNPVLSK ddPTM_PC-9_AZD4547_30min_R2 2 ASPVTTSPTAATTQNPVLSK 20 0 Q96JN0-3;Q96JN0-2;Q96JN0 Q96JN0-3 LCOR Ligand-dependent corepressor 1 ASPVT(0.025)T(0.887)S(0.087)PTAATTQNPVLSK;ASPVT(0.119)T(0.468)S(0.329)PT(0.073)AAT(0.007)T(0.004)QNPVLSK 282.41 4.080899999999999e-106 14065100.0 38966.0 34468.0 47279.0 65054.0 55379.0 45573.0 35126.0 53590.0 44605.0 50128.0 True False 51356.37745685024 45609.10694152311 46652.04956845017 50056.80537428088 47690.581761122005 42723.313105684465 38252.145951921404 45308.89687569068 46962.72923708771 48373.03397777571 1.0616736895280372 0.9428622352378715 0.9644226489883554 1.0348080584996746 0.9858918872658008 0.8832051577602734 0.7907741732614042 0.936656090178408 0.9708452287417833 1.0 15.561915406632819 -6.7113334714458786 7.064356274069155 0.9045618460211501 0.9955904344022588 0.29779643673995115 0.061367947676019885 0.2585875418503435 28.979105264131984 0.020997786976322316 0.02082136564157452 1.9438669172595543e-07 6.7113334714458786 0.09102858838110872 ASPVTTS(ph)PTAATTQNPVLSK ddPTM_PC-9_AZD4547_30min_R2 3 ASPVTTSPTAATTQNPVLSK 20 0 Q96JN0-3;Q96JN0-2;Q96JN0 Q96JN0-3 LCOR Ligand-dependent corepressor 1 ASPVT(0.002)T(0.207)S(0.791)PTAATTQNPVLSK;ASPVTT(0.043)S(0.771)PT(0.12)AAT(0.056)T(0.009)QNPVLSK;ASPVT(0.001)T(0.053)S(0.886)PT(0.053)AAT(0.003)T(0.005)QNPVLSK 263.19 6.206999999999998e-158 15053300.0 82367.0 73834.0 99891.0 138305.0 122282.0 111521.0 91013.0 120112.0 94707.0 115897.0 True False 108557.99265997004 97699.39659743593 98566.38007238015 106420.91904094943 105305.25504096382 104547.57424042825 99112.9806844567 101551.4502991783 99713.01867182738 111839.48130630142 0.9706589425487037 0.8735680410557414 0.8813200751747996 0.9515505418832206 0.9415749591377134 0.9348002424483498 0.8862074423701064 0.908010741046387 0.8915726137779325 1.0 16.771070049288532 -10.863861115500164 3.6024831921379357 1.000358114690864 0.9145536129630777 0.39552938937616866 0.03132951636644853 7405018.551567625 5582806.475132486 19119.26534484561 0.00772720557769344 1.3681662861632696e-11 10.863861115500164 -0.08580450172778631 ASPVTTS(ph)PTAATTQNPVLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASPVTTSPTAATTQNPVLSK 20 0 Q96JN0-3;Q96JN0-2;Q96JN0 Q96JN0-3 LCOR Ligand-dependent corepressor 1 ASPVTT(0.013)S(0.959)PT(0.028)AAT(0.001)TQNPVLSK;ASPVT(0.029)T(0.149)S(0.811)PT(0.011)AATTQNPVLSK 181.6 2.1497e-37 10197000.0 59570.0 62629.0 70929.8 68735.2 78283.0 70963.0 74896.7 59993.0 70200.0 65620.4 True False 69654.02443886951 68846.3932193584 72621.03543476434 64884.189586525 62944.0081092176 67241.5753567781 67801.9423708492 58418.24731783783 71226.54219464787 77516.85906919936 0.8985661348415744 0.888147353311867 0.9368418213376717 0.8370332643199956 0.8120041093644859 0.8674445296700103 0.8746734992232122 0.7536198966174289 0.9188522735559227 1.0 16.242222494457586 -5.770991581818003 24.997001369984172 0.854109362754206 0.9058813312011296 0.061596993270464306 0.06290117216073605 393.71200601103027 1030299.6373660474 0.016659268021119892 0.025068629192780644 1.6943706430985709e-06 5.770991581818003 0.051771968446923555 ASPVTTS(ph)PTAATTQNPVLSK ddPTM_PC-9_Lapatinib_30min_R1 2 ASPVTTSPTAATTQNPVLSK 20 0 Q96JN0-3;Q96JN0-2;Q96JN0 Q96JN0-3 LCOR Ligand-dependent corepressor 1 ASPVT(0.006)T(0.039)S(0.954)PT(0.001)AATTQNPVLSK;ASPVTT(0.033)S(0.964)PT(0.003)AATTQNPVLSK 211.26 9.917399999999998e-22 18095800.0 63996.0 52821.0 62089.0 46782.0 58898.0 68415.0 49556.0 54783.0 61427.0 46764.0 True False 63083.40530457095 52698.69621981258 56984.28209047094 50222.5043401771 55433.73543792328 65489.04993315436 52121.76720062974 57328.41817517404 54508.44440501363 54847.09509088679 1.1501685768414138 0.9608293043138545 1.0389662751699544 0.9156821205745481 1.0106959237506448 1.194029507390188 0.9503104424082821 1.0452407384598121 0.9938255492781891 1.0 15.743127591628186 -9.299520707149052 0.0038259923554198982 3.1642177857728673e-06 2.027314071002165 0.023116262514785935 0.08167204635573096 152161.62261160428 201.5555127905788 54036.7831419434 52758.12874649498 5.017406554856078e-10 9.299520707149052 2.0273109067843795 ASQCNVS(ph)LKK ddPTM_PC-9_AZD4547_30min_R2 1 ASQCNVSLKK 10 1 O15194-2;O15194 O15194-2 CTDSPL CTD small phosphatase-like protein 1 ASQCNVS(1)LKK 54.199 0.043711 19958000.0 62291.0 117280.0 81276.0 73691.0 63471.0 63464.0 79198.0 66091.0 56699.0 59084.0 True False 82098.24226671107 155188.4664645998 80198.22713520497 56702.678464600656 54659.14723920936 59495.5860474219 86246.46857314438 55878.1545700928 59695.99338669737 57015.487143769955 1.4399288049524608 2.721865132420554 1.4066042605753335 0.9945136191087779 0.9586719324414634 1.0434986883019721 1.5126849369131186 0.9800522168510241 1.0470136515043407 1.0 15.799066231996814 -5.477080904914573 7.076427190893178 1.0952431501714925 2.083551289709809 0.5995438543000124 0.3244544348556213 0.14571661817329662 18.69002091629114 0.08012187498564234 0.1649608925013907 3.3336430439195564e-06 5.477080904914573 0.9883081395383164 ASQEPS(ph)PKPGTEVIPAAPR ddPTM_PC-9_AZD4547_30min_R2 2 ASQEPSPKPGTEVIPAAPR 19 1 I3L4I0;I3L1Y9;Q96CP2 I3L4I0 FLYWCH2 FLYWCH family member 2 1 AS(0.022)QEPS(0.976)PKPGT(0.002)EVIPAAPR;AS(0.097)QEPS(0.893)PKPGT(0.01)EVIPAAPR 77.027 0.0016709 186919000.0 152006.0 155437.0 153553.0 226857.0 194646.0 162716.0 193221.0 184802.0 169817.0 209270.0 True False 200340.74607878597 205678.9705137962 151516.78689025203 174558.62355571138 167622.76273452686 152541.34279737022 210417.29468132425 156245.0972274938 178793.1799317232 201943.52099683048 0.9920632515956297 1.0184974962233344 0.7502928845765252 0.86439328528124 0.8300477376402569 0.7553663620620161 1.0419611069603305 0.7737069080317069 0.8853622985732202 1.0 17.623592334883924 -5.235810060074037 24.56551760954068 0.8560309663457584 1.0052804384237002 0.27396603491786775 0.09238129264833314 733.9487920702609 703481.145363021 0.02225043583138727 0.05881766625423164 5.810184720415814e-06 5.235810060074037 0.1492494720779418 ASQEPS(ph)PKPGTEVIPAAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASQEPSPKPGTEVIPAAPR 19 1 I3L4I0;I3L1Y9;Q96CP2 I3L4I0 FLYWCH2 FLYWCH family member 2 1 AS(0.005)QEPS(0.993)PKPGT(0.002)EVIPAAPR 68.08800000000001 0.0041031999999999996 73611000.0 56908.0 60906.0 64665.0 52437.0 66508.0 48612.0 56269.0 57126.0 37916.0 50270.0 True False 66541.40041576594 66952.3451662687 66206.8588433781 49499.12489304773 53476.2348316728 46062.70114346485 50938.79296771845 55626.50303000019 38470.44976997532 59383.553062898915 1.1205358551935323 1.1274560330762449 1.1149022823415762 0.8335493977704295 0.9005226543960901 0.7756811232678407 0.8577929467063752 0.9367324816533078 0.6478300436019299 1.0 15.857775795421526 -5.7587824893623845 23.99178647973719 0.8469606029846116 1.121613987207676 0.6592967579889234 0.08914046634345721 23.00961222470298 207768.06773010857 0.023072970866006463 0.03771581491647367 1.7426794527799177e-06 5.7587824893623845 0.2746533842230644 ASQEPS(ph)PKPGTEVIPAAPR ddPTM_PC-9_Lapatinib_30min_R1 2 ASQEPSPKPGTEVIPAAPR 19 1 I3L4I0;I3L1Y9;Q96CP2 I3L4I0 FLYWCH2 FLYWCH family member 2 1 AS(0.001)QEPS(0.998)PKPGT(0.001)EVIPAAPR;AS(0.012)QEPS(0.932)PKPGT(0.055)EVIPAAPR 87.79299999999999 0.00054477 184391000.0 130049.0 150119.0 131391.0 135546.0 122689.0 137055.0 123715.0 117245.0 111007.0 112527.0 True False 128194.47741193415 149771.40867878372 120588.53916392733 145514.50500820065 115472.6742358547 131193.4771408094 130120.35735785603 122692.63072391575 98504.22270446789 131977.1420171974 0.9713384867451491 1.1348283982332912 0.9137077627292001 1.1025735425399594 0.8749444977434649 0.9940621166331526 0.9859310132727422 0.9296506110726976 0.7463733582867874 1.0 17.00992855588396 -6.832860603396431 0.6946060501823735 0.8930734797371152 1.0345860162757154 0.2024997742308472 0.09370546463168311 1.103270173305027 1.1560674484367244 0.06911215585290038 0.06593658990414969 1.4693978383192863e-07 6.832860603396431 0.1415125365386003 ASQEPSPKPGT(ph)EVIPAAPR ddPTM_PC-9_AZD4547_30min_R2 1 ASQEPSPKPGTEVIPAAPR 19 1 I3L4I0;I3L1Y9;Q96CP2 I3L4I0 FLYWCH2 FLYWCH family member 2 1 AS(0.019)QEPS(0.352)PKPGT(0.629)EVIPAAPR 98.07700000000001 0.0058896 11102000.0 15324.0 11097.0 10864.0 16315.0 17044.0 14919.0 14765.0 14334.0 14099.0 16582.0 True False 20196.713240999146 14683.888236337532 10719.936261588507 12553.82881423729 14677.734800855273 13986.112571560065 16079.056396404934 12119.009662551793 14844.24435632102 16001.469227167983 1.2621786758623574 0.9176587491982671 0.6699344984764111 0.7845422589647492 0.917274194792987 0.8740517744341776 1.0048487528323475 0.7573685572557061 0.9276800864709237 1.0 13.965916756501779 -4.778684352773473 4.382499112122006 0.8584907284864669 1.291501163648119 0.5758973549535225 0.10078024556764609 0.1378384057802036 5.577157481126142 0.02540484847308923 0.18411742009774337 1.6646220657846757e-05 4.778684352773473 0.43301043516165216 ASQEPSPKPGT(ph)EVIPAAPR ddPTM_PC-9_Lapatinib_30min_R1 1 ASQEPSPKPGTEVIPAAPR 19 1 I3L4I0;I3L1Y9;Q96CP2 I3L4I0 FLYWCH2 FLYWCH family member 2 1 ASQEPS(0.003)PKPGT(0.997)EVIPAAPR 127.78 0.00034375 12428000.0 20452.0 15534.0 18504.0 18004.0 21187.0 15755.0 15362.0 14471.0 16118.0 13331.0 True False 20160.35072956255 15498.031977406117 16982.6725475056 19328.07421958336 19940.82231524467 15081.19537669879 16157.369193156717 15143.37548898278 14302.621109935526 15635.24558755907 1.2894169532971134 0.991224083473167 1.086178816469546 1.2361861610260005 1.2753763414571204 0.9645640224991966 1.0333940137155952 0.9685409419492796 0.9147679216063027 1.0 13.932514259840286 -6.781876015755941 24.988127766126176 0.9778584084565025 1.163818675681792 0.561477661505856 0.08780226906365987 207.27729922957008 253438.87018821412 0.03256610923521903 0.028753683404321564 1.652433474665478e-07 6.781876015755941 0.18596026722528958 ASQFTIVLEDEGSQGTDAPTPGNAENEPPEKET(ph)LSPPRR ddPTM_PC-9_AZD4547_30min_R2 1 ASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLSPPRR 39 2 P0C1Z6-2;P0C1Z6 P0C1Z6-2 TFPT TCF3 fusion partner 1 ASQFTIVLEDEGS(0.003)QGT(0.033)DAPT(0.033)PGNAENEPPEKET(0.514)LS(0.416)PPRR 44.84 0.0027107 5826600.0 7089.9 7291.3 8210.2 12403.0 10940.0 10927.0 9416.6 7618.9 11785.0 11554.0 True False 9344.340720918812 9648.070135857246 8101.327383550617 9543.679974439787 9421.169838145777 10243.7329626273 10254.659157628636 6441.574069904825 12407.931040445652 11149.497976763898 0.838095198581396 0.8653367313904445 0.7266091621734164 0.8559739635209841 0.8449860126240624 0.9187618118749152 0.9197417838004769 0.5777456602377418 1.1128690337721385 1.0 13.44469113160189 -8.30278611536279 24.99993231700091 1.0564346915585348 0.8257718903411163 0.4788277047009709 0.09909394861537765 494.3825723363697 298919.8203506367 0.09233752124357458 0.023842448638764766 4.979822746815146e-09 8.30278611536279 -0.23066280121741844 ASQGLLSSIENS(ph)ESDSSEAKEEGSR ddPTM_PC-9_AZD4547_30min_R2 1 ASQGLLSSIENSESDSSEAKEEGSR 25 1 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 ASQGLLS(0.182)S(0.139)IENS(0.384)ES(0.293)DS(0.001)SEAKEEGSR 62.781000000000006 0.00082739 6630400.0 4132.8 5843.9 10123.0 9737.6 8744.9 4632.7 6378.8 7311.7 6149.9 7873.6 True False 5446.944432419818 7732.826391306917 9988.762405749305 7492.746764420292 7530.8215829616975 4343.016536648991 6946.500842627014 6181.8447711511035 6474.971158730312 7597.947660537318 0.7168968089515132 1.0177519952486827 1.3146658613653717 0.9861540377984669 0.9911652355906234 0.571603902881039 0.9142601598463453 0.8136203416165584 0.8522000213768792 1.0 12.891394058504542 -6.5506102311917855 24.999682967835906 0.8192056441645713 1.0260090812179028 0.20854055272833916 0.16872407783729906 307.80879447259343 277484.68400094705 0.05636437707927491 0.056365303999235485 2.814425576259563e-07 6.5506102311917855 0.20680343705333148 ASQGLLSSIENS(ph)ESDSSEAKEEGSR ddPTM_PC-9_Lapatinib_30min_R1 2 ASQGLLSSIENSESDSSEAKEEGSR 25 1 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 AS(0.001)QGLLS(0.081)S(0.081)IENS(0.617)ES(0.177)DS(0.021)S(0.021)EAKEEGSR;AS(0.002)QGLLS(0.02)S(0.107)IENS(0.512)ES(0.344)DS(0.005)S(0.009)EAKEEGSR 61.256 0.0012648 11106500.0 15508.3 14143.599999999999 13918.0 11199.8 15577.6 16325.699999999999 14383.3 12582.900000000001 13122.7 10180.7 True False 15287.148798126089 14110.851363180192 12773.715765033667 12023.470653437556 14661.356194739948 15627.487868065478 15127.996895972597 13167.547470134841 11644.68333784285 11940.420430069955 1.2802856388228976 1.1817717345734635 1.0697877716989928 1.006955385185471 1.2278760434446487 1.308788744884582 1.2669568031185288 1.102770840210498 0.975232271429711 1.0 13.543566015289377 -8.063647128482899 4.001002601571799 0.9928102845022442 1.185779621326852 0.45491430397154053 0.08874286556285957 0.24931519749143782 7.68835876151016 0.07348998551132954 0.02645012934821212 8.636800171836896e-09 8.063647128482899 0.19296933682460793 ASQGLLSSIENSES(ph)DSSEAKEEGSR ddPTM_PC-9_AZD4547_30min_R2 1 ASQGLLSSIENSESDSSEAKEEGSR 25 1 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 ASQGLLS(0.001)S(0.005)IENS(0.273)ES(0.719)DS(0.002)SEAKEEGSR 88.84200000000001 3.4258999999999997e-06 5853100.0 17118.0 12544.0 18112.0 21161.0 17929.0 15794.0 15313.0 16735.0 16582.0 17966.0 True False 22561.167923481044 16598.60268871027 17871.82304582943 16282.658384190945 15439.867827067232 14806.398683237454 16675.82733478827 14148.990282042987 17458.490667176055 17337.01580842481 1.3013293736813454 0.9574082917225171 1.0308477100854194 0.9391846073231641 0.8905724028678758 0.854033868737801 0.9618626134426642 0.8161145169612971 1.007006676356159 1.0 14.081567970791117 -2.0099601047964253 1.085026577629822 0.9191239321147071 199.99999999985374 0.7225455882066549 0.06663253337475729 411.62187201132343 1.2235308990738722 0.01938205155672754 203015.4000347483 0.00977326996143541 2.0099601047964253 199.08087606773904 ASQMVNSCITSPSTPS(ph)KK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASQMVNSCITSPSTPSKK 18 1 Q86T82 Q86T82 USP37 Ubiquitin carboxyl-terminal hydrolase 37 1 ASQMVNSCITSPS(0.039)T(0.133)PS(0.827)KK 109.83 0.00050594 0.0 15545.0 14496.0 20120.0 17340.0 18529.0 12829.0 10425.0 10453.0 14333.0 7547.7 True False 18176.461472254923 15935.067079273489 20599.73710552492 16368.496017038506 14898.375461539441 12156.224655836231 9437.46852953606 10178.619825868996 14542.593009628019 8916.038262439675 2.0386253330502577 1.787236282554177 2.3104137173014174 1.8358485613496718 1.6709636077159267 1.3634110013913232 1.0584822823487645 1.1416079121988698 1.6310599597683604 1.0 13.122187092479304 -6.5593645751019745 1.7551147694441314 1.2175560917019383 2.014531965308135 0.7582749094341374 0.20333776492291744 0.1740204738766379 1.0908979996502053 0.0787212509054408 0.08361217456587873 2.7582614196117194e-07 6.5593645751019745 0.7969758736061967 ASQPDLVDT(ph)PTSSKPQPK ddPTM_PC-9_AZD4547_30min_R2 2 ASQPDLVDTPTSSKPQPK 18 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 AS(0.007)QPDLVDT(0.769)PT(0.131)S(0.067)S(0.027)KPQPK;ASQPDLVDT(0.958)PT(0.021)S(0.016)S(0.005)KPQPK 88.133 0.0011332 29503000.0 118895.0 133022.0 139274.0 174950.0 161452.0 149575.0 104940.0 153678.0 127442.0 159862.0 True False 156701.1368303701 176018.76011301167 137427.13575998496 134617.98045055548 139037.17666437937 140222.05160473843 114279.4567042828 129930.59626912452 134178.32394200042 154265.2800382059 1.0157900519907066 1.1410134546763744 0.8908494233177371 0.8726395234054967 0.9012862559219087 0.9089670181781054 0.7407982967779914 0.8422543052911545 0.869789520420728 1.0 17.235053870414767 -5.333860711855974 6.08109009525348 0.8683472568720231 1.0776092876180898 0.5839182453122118 0.06723280966550664 0.1325335781352386 8.708211997820866 0.01748587461006892 0.037270915890277125 4.635955815702672e-06 5.333860711855974 0.20926203074606675 ASQPDLVDT(ph)PTSSKPQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASQPDLVDTPTSSKPQPK 18 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ASQPDLVDT(0.954)PT(0.034)S(0.008)S(0.004)KPQPK;AS(0.003)QPDLVDT(0.483)PT(0.184)S(0.147)S(0.184)KPQPK 94.20299999999999 0.00070096 14587800.0 101836.0 95086.0 84060.0 104512.0 104338.0 79659.0 89284.0 81079.0 71418.0 62763.0 True False 119074.82344731732 104525.50967851833 86064.30919932527 98656.53147247568 83893.7178965999 75481.54180834498 80826.37315981738 78950.76216030162 72462.3531404181 74141.43506836548 1.6060496177005337 1.4098123347914135 1.1608125620979115 1.330653114301132 1.1315362026543172 1.0180750040614104 1.0901646708792154 1.064866927481259 0.97735298856302 1.0 16.177992419524124 -1.522878748895005 0.34052395893196974 0.9966612521188866 7.778296982078702 0.8894578886673064 0.06487557103324941 18.506035137434544 0.2621501755368461 0.057827012360819836 79.83213145864273 0.029999999750307614 1.522878748895005 6.781635729959816 ASQPDLVDT(ph)PTSSKPQPK ddPTM_PC-9_Lapatinib_30min_R1 2 ASQPDLVDTPTSSKPQPK 18 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ASQPDLVDT(0.845)PT(0.134)S(0.018)S(0.003)KPQPK;ASQPDLVDT(0.986)PT(0.008)S(0.005)S(0.001)KPQPK 110.75 0.00015723 31240000.0 200969.0 182251.0 200423.0 151107.0 153265.0 165135.0 159397.0 130367.0 137344.0 93864.0 True False 198103.14520679903 181829.00900696812 183944.994595153 162219.91285817546 144250.2540305835 158072.56099848665 167649.79672448896 136424.3267481323 121874.87242356283 110088.26733408183 1.79949371539858 1.6516656443976598 1.6708864536575927 1.4735440641089497 1.3103145096546143 1.4358710953165263 1.5228670664397572 1.2392267591434531 1.1070650431231923 1.0 16.748301196192095 -1.522878745295172 0.11198436542779998 0.7698008757844027 3.9318936845261194 0.8572143364215363 0.09204488572111061 40.99235441876651 0.3207284229542766 0.8804670789750069 20.05662431205312 0.029999999998975273 1.522878745295172 3.1620928087417166 ASQS(ph)RPNS(ph)SALETLGGEK ddPTM_PC-9_AZD4547_30min_R2 1 ASQSRPNSSALETLGGEK 18 1 O94804 O94804 STK10 Serine/threonine-protein kinase 10 2 AS(0.132)QS(0.868)RPNS(0.835)S(0.163)ALET(0.002)LGGEK 73.98100000000001 0.020957 8678200.0 47447.0 43354.0 71443.0 90494.0 90112.0 84168.0 70951.0 88820.0 74270.0 78005.0 True False 62534.159041091516 57367.33266632219 70495.6191399731 69632.00641836275 77601.50424634301 78904.9616544718 77265.50154970026 75094.90988055328 78195.76057478998 75274.0686928742 0.8307530086654037 0.7621128186970562 0.9365193135447791 0.9250464021344238 1.0309194865361269 1.0482356410998854 1.026455762142356 0.9976199132658564 1.0388140555260348 1.0 16.19986533327345 -5.627805331071926 1.3303144398332463 1.0243698951612155 0.7879217953357156 0.8661983866681207 0.03354394271889574 0.15331647494953393 0.5186846092303984 0.01069291471031197 0.03213549901450923 2.356105151984236e-06 5.627805331071926 -0.23644809982549986 ASQS(ph)RPNSSALETLGGEK ddPTM_PC-9_AZD4547_30min_R2 1 ASQSRPNSSALETLGGEK 18 1 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 AS(0.413)QS(0.576)RPNS(0.009)S(0.002)ALETLGGEK 74.561 0.0029408 14643000.0 17770.0 26091.0 24988.0 40513.0 45542.0 36244.0 37964.0 42237.0 22858.0 31295.0 True False 23420.49036103855 34524.40551268654 24656.642793130854 31173.35376961049 39219.27941214211 33977.65695044057 41342.72245398691 35710.24215970418 24066.22721446811 30199.37157545665 0.7755290636601403 1.143216024426975 0.8164621151643291 1.0322517371502329 1.2986786600558282 1.125111390663989 1.3689928067108053 1.1824829556627687 0.7969115236168354 1.0 14.882230908093007 -4.756436702331346 24.89233347385899 1.0973844240478314 0.7755285392212489 0.21612987188640165 0.1753079830855736 239.0115328522095 1189130.8214098478 0.04549405412542832 0.367782839231511 1.7521177837325114e-05 4.756436702331346 -0.32185588482658256 ASQSRPNS(ph)SALETLGGEK ddPTM_PC-9_AZD4547_30min_R2 3 ASQSRPNSSALETLGGEK 18 1 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 ASQS(0.003)RPNS(0.636)S(0.36)ALET(0.001)LGGEK;ASQSRPNS(0.97)S(0.023)ALET(0.007)LGGEK;AS(0.003)QS(0.003)RPNS(0.927)S(0.059)ALET(0.008)LGGEK 141.22 4.6835e-05 88693000.0 139740.0 126544.0 204388.0 285149.0 254588.0 224630.0 184276.0 245733.0 172824.0 212061.0 True False 184174.41322743567 167446.87329720616 201677.68157525326 219412.3035581335 219242.85070876227 210583.8505898213 200676.20701008535 207760.61123258265 181959.123812811 204636.80893634527 0.900006280320396 0.8182637042062775 0.9855396134426017 1.0722035038495168 1.0713754375292295 1.0290614463956282 0.9806457012946682 1.0152651046137504 0.8891808114023688 1.0 17.642706146859283 -5.3613553181150415 5.2805434359498635 1.0122138337786541 0.8601691049011682 0.5576002042500979 0.052199282171012495 0.15057288604287253 6.281948151387577 0.014294493280215188 0.03073570446207624 4.351557052806953e-06 5.3613553181150415 -0.152044728877486 ASQSRPNS(ph)SALETLGGEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASQSRPNSSALETLGGEK 18 1 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 ASQS(0.001)RPNS(0.913)S(0.087)ALETLGGEK;AS(0.014)QS(0.053)RPNS(0.874)S(0.053)ALET(0.005)LGGEK;AS(0.005)QS(0.005)RPNS(0.895)S(0.096)ALETLGGEK 135.98 3.7453e-05 52435000.0 126121.0 134785.0 144723.0 190155.0 217664.0 183875.0 186002.0 205931.0 178228.0 128437.0 True False 147470.7942967039 148165.56403696694 148173.74518503406 179501.2318408278 175014.30171409828 174232.27130656235 168382.54402213608 200525.52945193075 180834.24732575056 151721.6113932675 0.9719827844067295 0.9765620248582573 0.9766159469593475 1.1830960018975452 1.1535225608727246 1.1483681837187087 1.1098125209445797 1.3216675436709004 1.1918819320803424 1.0 17.21106707372794 -5.758668742214408 24.96253850489667 1.1691007212356312 0.9752043755020999 0.5511540551626699 0.07535805688877588 49.427972271521895 445319.39534636866 0.020549010510274537 0.03364773402104843 1.7431359420674757e-06 5.758668742214408 -0.19389634573353132 ASQSRPNS(ph)SALETLGGEK ddPTM_PC-9_Lapatinib_30min_R1 2 ASQSRPNSSALETLGGEK 18 1 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 AS(0.031)QS(0.031)RPNS(0.715)S(0.219)ALET(0.003)LGGEK;ASQSRPNS(0.995)S(0.004)ALETLGGEK 131.98 0.00019511 40422000.0 77385.0 76454.0 91877.0 93664.0 96287.0 106734.0 95894.0 83370.0 112030.0 74104.0 True False 76281.47570932891 76276.97546031972 84323.22771547624 100552.36301394428 90623.58796752561 102169.23562910633 100858.92210705433 87243.67455714817 99412.00167180023 86912.77766262676 0.877678492861362 0.8776267139500188 0.9702051871221687 1.1569341783582492 1.042695796920716 1.1755375719977705 1.1604613823132306 1.0038072295400093 1.1438134224370584 1.0 16.40728067299146 -5.550785814991283 3.6854061064883106 1.1010633847456421 0.8827365378704832 0.679179979373971 0.06148257018601619 0.11972875434447613 3.476742594631024 0.01655470123223743 0.03259374195976401 2.8132879434435973e-06 5.550785814991283 -0.2183268468751589 ASQSRPNSS(ph)ALETLGGEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASQSRPNSSALETLGGEK 18 1 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 ASQSRPNS(0.376)S(0.62)ALET(0.004)LGGEK 112.74 0.0028703 0.0 5782.4 7449.6 11048.0 8558.6 10997.0 11460.0 11727.0 10994.0 10428.0 11687.0 True False 6761.246112394138 8189.147055308761 11311.426219773315 8079.089389355576 8842.216792625033 10859.017425822998 10616.13366387236 10705.419149105877 10580.48977216222 13805.760585758911 0.4897409360675559 0.5931688445876812 0.8193265520945957 0.585196979128366 0.6404729922483275 0.7865569852793497 0.7689640565564526 0.7754313196006646 0.7663822435886899 1.0 13.752982750494338 -7.083851990455111 0.07098235239913175 1.4603552161783118 5.635183143140772e-17 0.7026464639137542 0.07592331350913452 22.042069128054017 0.8155639530826396 7.023987631364131 9.25997848035745 8.244190329166303e-08 7.083851990455111 -1.4603552161783118 ASREES(ph)WESGR ddPTM_PC-9_AZD4547_30min_R2 1 ASREESWESGR 11 1 Q9NQ29-3;Q9NQ29;B8ZZ08 Q9NQ29-3 LUC7L Putative RNA-binding protein Luc7-like 1 1 AS(0.002)REES(0.997)WES(0.001)GR 97.631 0.021909 0.0 15504.0 9912.0 44118.0 64152.0 41807.0 22397.0 14586.0 49029.0 13356.0 18471.0 True False 20433.949496766556 13115.86016027554 43532.96649381087 49362.74753851982 36002.819691349214 20996.512049415564 15884.125743173874 41452.694624337346 14061.970893185598 17824.33591213484 1.1464073386798712 0.7358400461554497 2.4423331510585786 2.769401776417015 2.019868783264931 1.1779688260431123 0.8911482493078428 2.3256235087062223 0.7889197646691669 1.0 14.121560706198009 -6.7646283232716975 24.99321578216854 1.297984501934378 1.8493960339811488 0.15540383108585076 0.6741772344285847 192.60544865767255 1509524.090635725 0.2529982942666001 0.2324466270611928 1.7193792321623515e-07 6.7646283232716975 0.5514115320467707 ASS(ph)APAAAAGLLR ddPTM_PC-9_Lapatinib_30min_R1 1 ASSAPAAAAGLLR 13 0 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 AS(0.259)S(0.741)APAAAAGLLR 71.806 0.025047999999999997 1802600.0 15957.0 16014.0 20343.0 14814.0 18497.0 16613.0 12961.0 18871.0 16929.0 13840.0 True False 15729.450253844594 15976.920566897234 18670.477066250885 15903.470978055322 17409.04282650119 15902.500716794491 13632.057161339946 19747.815551972493 15022.277749726929 16232.225559359202 0.9690261015856376 0.984271719763359 1.1502105486382816 0.9797467956503151 1.072498824196258 0.9796870218837862 0.8398144241828843 1.2165808982728352 0.9254601406807929 1.0 13.98657319726208 -6.788713532774425 24.953901864082923 0.99631392576623 1.0323051015782603 0.03456909835244937 0.10144505068718344 1034.3439841636816 946343.3001262868 0.0353398927350398 0.031175205004429104 1.6266213460678924e-07 6.788713532774425 0.03599117581203026 ASS(ph)ASVPAVGASAEGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSASVPAVGASAEGTR 17 0 V9GYZ0;Q9BZ23-3;Q9BZ23-4;Q9BZ23;A0A2R8YFI4 V9GYZ0 PANK2 Pantothenate kinase 2, mitochondrial 1 AS(0.083)S(0.916)AS(0.002)VPAVGASAEGTR 66.289 0.020334 23024000.0 16503.0 21899.0 19143.0 20222.0 23882.0 17410.0 23035.0 17165.0 17471.0 17628.0 True False 19296.631950892446 24072.987994550935 19599.441720231778 19089.026900608565 19202.49353837147 16496.988951446638 20852.95804104203 16714.436937820847 17726.480323115287 20823.816856828787 0.9266616242144134 1.1560314883703293 0.9412031355723579 0.9166920277801363 0.9221409153948819 0.7922173473225085 1.0013994160827286 0.8026596206035905 0.8512599032632298 1.0 14.345946908116234 -5.480899201600835 6.994942324929198 0.8933856222212493 1.0440163032794882 0.309831443925599 0.08425302339604678 0.239075792151629 32.241955959217094 0.021010414254509526 0.04307629192182164 3.304462276792963e-06 5.480899201600835 0.15063068105823896 ASS(ph)ASVPAVGASAEGTRR ddPTM_PC-9_AZD4547_30min_R2 1 ASSASVPAVGASAEGTRR 18 1 V9GYZ0;Q9BZ23-3;Q9BZ23-4;Q9BZ23;A0A2R8YFI4 V9GYZ0 PANK2 Pantothenate kinase 2, mitochondrial 1 AS(0.169)S(0.701)AS(0.13)VPAVGASAEGTRR 101.61 0.000236 14997000.0 6788.7 12325.0 17743.0 24836.0 21178.0 13936.0 13035.0 18267.0 9625.1 22001.0 True False 8947.365386268006 16308.815221488687 17507.716226929737 19110.443912374943 18237.8002588895 13064.579716955626 14195.089747859009 15444.254883900763 10133.8631359689 21230.751686583222 0.42143422514438317 0.7681694676781061 0.8246394892364429 0.9001303483970279 0.8590275336513347 0.6153611473498506 0.6686098522281525 0.7274473891407606 0.47732003489885844 1.0 14.37386783111812 -6.772868289939527 24.99207062412053 0.6788920490819599 0.7673968172874291 0.018104004662219952 0.17298062322090121 737.8792803128916 1613541.8298483326 0.06026790443415153 0.05361002180756071 1.687064590001284e-07 6.772868289939527 0.08850476820546926 ASS(ph)CETYEYPQR ddPTM_PC-9_AZD4547_30min_R2 1 ASSCETYEYPQR 12 0 Q9UQC2-2;Q9UQC2 Q9UQC2-2 GAB2 GRB2-associated-binding protein 2 1 AS(0.004)S(0.992)CET(0.004)YEYPQR 154.67 0.00027929 9397500.0 7352.4 5931.9 9769.6 13175.0 12938.0 10391.0 7698.8 14890.0 9220.0 11057.0 True False 9690.310260579621 7849.270670373127 9640.048720656758 10137.707301720888 11141.782026136198 9741.249127359777 8383.978285448173 12589.092638160742 9707.350376996941 10669.897795488876 0.9081914790858245 0.7356462846056238 0.9034808866428385 0.9501222500938113 1.044225749833033 0.9129655516923768 0.785759943173292 1.1798700305717345 0.9097885062311571 1.0 13.381258736532073 -5.555622445785747 3.5671900940163415 0.9691751451568412 0.8201557368570778 0.24163894926542806 0.10346262129061293 0.30721039711516823 8.220354773708364 0.02837565441895232 0.056035816079096294 2.7821308641671147e-06 5.555622445785747 -0.14901940829976346 ASS(ph)CETYEYPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSCETYEYPQR 12 0 Q9UQC2-2;Q9UQC2 Q9UQC2-2 GAB2 GRB2-associated-binding protein 2 1 AS(0.125)S(0.866)CET(0.009)YEYPQR 173.76 0.0011551999999999999 4194300.0 10583.0 9437.0 10247.0 14799.0 16628.0 16027.0 16711.0 16700.0 14164.0 12033.0 True False 12374.492876222179 10373.842993039732 10491.327341963904 13969.860009005342 13369.862765096748 15186.515906078994 15128.013102837129 16261.64269511262 14371.121704344618 14214.487646824413 0.8705549706525442 0.7298077321385059 0.7380728452993323 0.982790259916704 0.9405799981882317 1.0683829261670037 1.0642672095337042 1.1440189121938245 1.011019324889645 1.0 13.795074478374463 -6.078046032787991 1.4709070565846507 1.0621971444555565 0.7725433463069818 0.7515355512850642 0.06529024595915894 0.18444164643594926 0.8034788235522984 0.02302443057464199 0.03751854657854623 8.355144536749099e-07 6.078046032787991 -0.2896537981485746 ASS(ph)CETYEYPQR ddPTM_PC-9_Lapatinib_30min_R1 1 ASSCETYEYPQR 12 0 Q9UQC2-2;Q9UQC2 Q9UQC2-2 GAB2 GRB2-associated-binding protein 2 1 AS(0.12)S(0.701)CET(0.179)YEYPQR 148.13 0.00014484 10466000.0 11841.0 14319.0 13688.0 14492.0 14718.0 13479.0 17246.0 13133.0 16793.0 15511.0 True False 11672.145168626546 14285.84523525673 12562.625477207988 15557.790023894815 13852.316176701337 12902.53459108366 18138.91349467392 13743.207124373632 14901.595501870414 18192.055682891652 0.6416067195530507 0.7852793265519499 0.6905555752570751 0.8551969219468596 0.7614486464950998 0.709240055988702 0.9970788244526039 0.7554510256528156 0.8191265331209554 1.0 14.151020954751345 -14.522877519170484 0.03275511859856274 2.2149064382038164 1.9117960830513695e-07 0.47838534891757234 0.08273274710225959 1109.0074332083987 2.7192877161107813 149.4233827608601 55.591782629712355 3.000008469678771e-15 14.522877519170484 -2.2149062470242082 ASS(ph)DGEGTMSR ddPTM_PC-9_AZD4547_30min_R2 1 ASSDGEGTMSR 11 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 AS(0.157)S(0.843)DGEGTMSR 92.11200000000001 0.0068904 2537100.0 19068.0 28340.0 26865.0 20315.0 22925.0 29878.0 26682.0 28617.0 28638.0 21440.0 True False 25131.227360961366 37500.35078109451 26508.75254672083 15631.690613621242 19742.259464304563 28009.723936796796 29056.64631011694 24194.900203240162 30151.746214364233 20689.39212582812 1.2146914326007756 1.8125399989050432 1.281272663087475 0.7555413188822996 0.9542213393335429 1.3538205359755426 1.4044224273676629 1.1694350445915642 1.4573529290270228 1.0 14.3366036376069 -5.510718062251638 24.96795821275214 1.1616574734977756 1.521938423884582 0.2511849831662559 0.24419274498497015 759.2703633217513 1558909.3124842471 0.06746880177396354 0.12959226951456285 3.085190161476129e-06 5.510718062251638 0.3602809503868063 ASS(ph)DGEGTMSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSDGEGTMSR 11 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 AS(0.023)S(0.977)DGEGTMSR 99.539 0.0039805 2614100.0 17819.0 27368.0 25839.0 20160.0 28876.0 20533.0 28022.0 19644.0 17995.0 18155.0 True False 20835.40475870764 30084.914171189084 26455.099754953182 19030.500559601864 23217.955088100425 19456.213333719337 25367.553298288673 19128.365814538447 18258.142831804664 21446.357785099066 0.9715125042436847 1.4027982966922286 1.23354744055115 0.8873534961178471 1.0826059753713642 0.9072036160488528 1.182837363457307 0.8919167537076548 0.8513400277454303 1.0 14.388445036526367 -5.749664728417847 24.99748379833029 0.9780973101817064 1.2226374002520977 0.37265838235687665 0.1362776056028946 218.98102101612963 464890.589455835 0.03595183924017298 0.06163137824584621 1.7796527563938684e-06 5.749664728417847 0.24454009007039124 ASS(ph)DGEGTMSRPASVDGSPVSPSTNR ddPTM_PC-9_AZD4547_30min_R2 1 ASSDGEGTMSRPASVDGSPVSPSTNR 26 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 AS(0.125)S(0.832)DGEGT(0.017)MS(0.017)RPAS(0.005)VDGS(0.002)PVS(0.002)PS(0.001)T(0.001)NR 53.995 0.0093944 12361000.0 17854.0 17566.0 21909.0 34081.0 26070.0 22768.0 16515.0 24311.0 17440.0 19434.0 True False 23531.200613730012 23243.865978147714 21618.472344913705 26224.15199620111 22450.63050095615 21344.31336076677 17984.80300620572 20554.29356120389 18361.842795534343 18753.621575249217 1.2547550092823767 1.2394334547533294 1.1527625348612922 1.3983513472838442 1.1971357324702658 1.1381435460410865 0.9590042613391445 1.096017293445399 0.9791091668271723 1.0 14.194881605778107 -6.924513467995567 2.471796871124957 1.016985194543374 1.253853569574607 0.735717649969095 0.06769338724242088 0.15162199848105154 1.8798025508599854 0.026799718410800873 0.02241354477349185 1.1898344303874876e-07 6.924513467995567 0.23686837503123281 ASS(ph)DGEGTMSRPASVDGSPVSPSTNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSDGEGTMSRPASVDGSPVSPSTNR 26 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 AS(0.029)S(0.963)DGEGT(0.004)MS(0.004)RPASVDGSPVSPSTNR 57.04600000000001 0.0061443 7313500.0 6380.2 6260.8 7328.9 7202.8 11374.0 9240.9 6907.1 8089.4 8335.2 6758.2 True False 7460.24184530594 6882.330847814262 7503.648771008024 6799.250467792675 9145.346348942176 8756.290936325282 6252.8094849264735 7877.06182142778 8457.086531350833 7983.408162118237 0.9344682989785299 0.8620792909563794 0.9399054412141044 0.851672660312614 1.1455441289269672 1.0968111310999256 0.7832255795959976 0.986679080095757 1.059332851285273 1.0 12.96278905728799 -6.2107906024745585 24.99999149013671 1.0040751567162645 0.8975972626149363 0.2640389420368425 0.09342414767168544 587.2835139825542 289879.95872688823 0.02923561744562878 0.03774301964857171 6.154735552145241e-07 6.2107906024745585 -0.10647789410132813 ASS(ph)DGEGTMSRPASVDGSPVSPSTNR ddPTM_PC-9_Lapatinib_30min_R1 1 ASSDGEGTMSRPASVDGSPVSPSTNR 26 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 AS(0.07)S(0.854)DGEGT(0.055)MS(0.019)RPAS(0.001)VDGSPVSPSTNR 63.427 0.0013344000000000001 7514400.0 14053.0 16250.0 17127.0 12661.0 24296.0 24202.0 20491.0 24693.0 26470.0 20667.0 True False 13852.601642995425 16212.374123397021 15718.884172131879 13592.132175857872 22866.95704777384 23166.936877617532 21551.92371676698 25840.326926228423 23488.669858542842 24239.2634129535 0.5714943316137475 0.6688476397650394 0.6484885247681117 0.5607485650159739 0.9433849807314567 0.9557607623190846 0.8891327821970696 1.0660524821236652 0.9690339784001217 1.0 14.565058238152998 -6.290579232618346 7.821251397209033 0.9696870649769812 0.6189794392760247 0.9205629703917855 0.05153113522567802 0.06606943400089241 15.578680877049928 0.01622803610779894 0.018686422974191187 5.121778200977179e-07 6.290579232618346 -0.3507076257009565 ASS(ph)DIVSLAGPSAGPGSSEGGCSR ddPTM_PC-9_AZD4547_30min_R2 1 ASSDIVSLAGPSAGPGSSEGGCSR 24 0 V9GZ26;Q9BQ89 V9GZ26 FAM110A Protein FAM110A 1 AS(0.017)S(0.983)DIVSLAGPSAGPGSSEGGCSR 304.29 9.258799999999993e-299 0.0 3944.7 5435.7 6015.9 8790.0 8675.4 7686.9 6958.6 9086.2 5513.5 6438.9 True False 5199.03254514287 7192.683724092988 5936.125235280766 6763.601304146232 7470.970458304377 7206.236927831957 7577.901919405582 7682.136570104514 5804.932353966661 6213.476070848626 0.8367349428663359 1.1575941778931844 0.9553630154191647 1.088537434927704 1.2023817864778554 1.159775437398239 1.2195913902297535 1.236366967943485 0.9342487663550032 1.0 12.601184881149909 -4.756275356329372 24.984028154993982 1.1163622870369359 0.8367345051364394 0.37000326966867025 0.10461453952973426 174.38409976733718 843592.5050985995 0.026347066761605097 0.21659799137979235 1.7527688390198946e-05 4.756275356329372 -0.2796277819004964 ASS(ph)EDTLNKPGSTAASGVVR ddPTM_PC-9_AZD4547_30min_R2 1 ASSEDTLNKPGSTAASGVVR 20 1 Q5M775;Q5M775-2;J3KRD8;J3KRB9;J3KTI9;J3QRQ9;J3QS22 Q5M775 SPECC1 Cytospin-B 1 AS(0.244)S(0.75)EDT(0.006)LNKPGSTAASGVVR 68.406 0.0024083999999999998 15945000.0 24489.0 14630.0 24937.0 30053.0 28927.0 26108.0 23820.0 29941.0 18921.0 24945.0 True False 32275.99259715663 19358.861394756965 24606.319086453645 23124.74516422146 24910.985366365894 24475.462632769624 25939.933854545594 25314.306425733434 19921.125432012926 24071.68314266706 1.3408282422905204 0.8042171907972393 1.0222101604037377 0.9606617463002761 1.034866785954455 1.0167740447441693 1.0776119684197345 1.0516217862997632 0.8275750936876836 1.0 14.555049401157552 -4.741788141206531 24.998284246686172 0.985948850830545 1.3408294601427377 0.6078013000004348 0.08736055289647114 981.8879931725701 1248992.6037836978 0.0213202773080098 0.8244398967246211 1.81222392135428e-05 4.741788141206531 0.3548806093121928 ASS(ph)EDTLNKPGSTAASGVVR ddPTM_PC-9_Lapatinib_30min_R1 3 ASSEDTLNKPGSTAASGVVR 20 1 Q5M775;Q5M775-2;J3KRD8;J3KRB9;J3KTI9;J3QRQ9;J3QS22 Q5M775 SPECC1 Cytospin-B 1 AS(0.223)S(0.755)EDT(0.021)LNKPGST(0.001)AASGVVR;AS(0.245)S(0.747)EDT(0.008)LNKPGSTAASGVVR;AS(0.163)S(0.837)EDTLNKPGSTAASGVVR 156.83 2.4289e-20 29407000.0 37508.2 33062.6 38210.0 31584.3 35191.4 36311.6 31979.2 33122.3 38686.5 33578.5 True False 36973.32618983855 32986.04558106009 35068.52129486538 33907.114784136116 33121.51104095443 34758.63751447388 33634.92650057266 34661.28297690099 34329.21898309472 39382.4989844612 0.9388263097379064 0.837581322456838 0.8904595238789202 0.8609691019738118 0.8410210599896896 0.8825909581864849 0.8540576999403643 0.8801189327923803 0.8716871673542019 1.0 15.26526703873463 -11.044436331057158 3.084429100493553 1.0043090956144791 0.8711392594959885 0.6558707472825926 0.027559641474587376 24367544.073496327 31317815.14407624 894164.8523688866 0.006433252757367106 9.027420426052786e-12 11.044436331057158 -0.13316983611849065 ASS(ph)ESQGLGAGVR ddPTM_PC-9_AZD4547_30min_R2 2 ASSESQGLGAGVR 13 0 Q9BV36-2;H7C2D8;Q9BV36-3 Q9BV36-2 MLPH Melanophilin 1 AS(0.001)S(0.998)ES(0.001)QGLGAGVR;AS(0.006)S(0.739)ES(0.256)QGLGAGVR 141.82 6.9292e-05 15958600.0 37699.0 40334.0 49662.0 78909.0 61979.0 50629.0 53866.0 47267.0 53761.0 56754.0 True False 49686.49781208737 53371.17672564095 49003.44943142565 60717.749181897 53374.28568541471 47463.16062641694 58659.969647731 39962.97123760537 56602.69670474321 54767.05973457317 0.90723325394665 0.9745123617061546 0.8947613705924569 1.1086545357038273 0.9745691286713491 0.8666370050984232 1.0710812289727565 0.7296899163709838 1.0335171721663787 1.0 15.741020808387413 ASS(ph)ESQGLGAGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASSESQGLGAGVR 13 0 Q9BV36-2;H7C2D8;Q9BV36-3 Q9BV36-2 MLPH Melanophilin 1 AS(0.151)S(0.802)ES(0.048)QGLGAGVR;AS(0.063)S(0.875)ES(0.063)QGLGAGVR 137.73 6.9327e-05 3749200.0 24808.0 19183.6 30478.0 33937.0 42361.0 49559.0 62842.0 68915.0 55029.0 48900.0 True False 29007.504419665474 21088.021028004332 31204.71110845866 32035.61991523849 34060.666140982896 46960.03879636667 56889.150823319425 67106.05427147837 55833.695020360086 57765.18290781299 0.5021624265599285 0.3650645590728682 0.5401992954520376 0.5545835450112552 0.5896400639004303 0.8129471150694674 0.9848346003527485 1.1617041770398684 0.966563113103349 1.0 15.817912571565756 -6.885242261894008 1.3519317462815734 1.0596005966325703 0.4738984891054638 0.9311316870341412 0.06718753609533826 0.09799544350055786 0.37134896689433106 0.03397776704456737 0.027478480693093138 1.302440037436478e-07 6.885242261894008 -0.5857021075271065 ASS(ph)ESQGLGAGVR ddPTM_PC-9_Lapatinib_30min_R1 3 ASSESQGLGAGVR 13 0 Q9BV36-2;H7C2D8;Q9BV36-3 Q9BV36-2 MLPH Melanophilin 1 AS(0.005)S(0.946)ES(0.049)QGLGAGVR;AS(0.061)S(0.821)ES(0.118)QGLGAGVR;AS(0.019)S(0.978)ES(0.002)QGLGAGVR 178.67 0.00012108 13739500.0 29164.800000000003 24799.6 33415.9 29501.1 49896.0 75855.0 71150.0 63584.0 86688.0 79870.0 True False 28748.9046038307 24742.17804988287 30668.57369110421 31670.709306784636 46961.21537931034 72610.85847664156 74833.79886037631 66538.34476480413 76924.28457489086 93675.42307991457 0.3068991167438335 0.2641266752409039 0.32739188874482933 0.338089845399111 0.5013184230750438 0.775132431637882 0.7988626728329322 0.7103073845531525 0.8211789394243428 1.0 16.51538296797164 -6.584137610587919 1.7457645980984637 0.8160623337492564 0.2964106779376772 0.9238799164480265 0.06980942748219794 0.08984136482446113 0.5592832769781789 0.02672364563433087 0.027870968349831857 2.605327894770212e-07 6.584137610587919 -0.5196516558115791 down ASS(ph)ESQIFELNK ddPTM_PC-9_AZD4547_30min_R2 1 ASSESQIFELNK 12 0 Q9BV36;Q9BV36-4;H7C371 Q9BV36 MLPH Melanophilin 1 AS(0.178)S(0.775)ES(0.047)QIFELNK 90.689 0.02404 0.0 12628.0 12202.0 19525.0 23380.0 25155.0 15754.0 15101.0 19563.0 20506.0 22291.0 True False 16643.441321282786 16146.05787688479 19266.085742591644 17990.1022173992 21662.66245690648 14768.899889560771 16444.959745486693 16539.98786301805 21589.905296171277 21510.598874852334 0.7737321223882959 0.7506094075214644 0.8956554791747471 0.8363366506932131 1.0070692398170245 0.6865871087776563 0.7645049699063566 0.7689227045349566 1.003686853247571 1.0 14.392760070826103 -8.269521883653342 24.47107622570938 1.0018434882075058 0.8130338631256221 0.45288278652995917 0.08411714975091504 480.0383405034781 1453368.8459118234 0.07902943305428757 0.021892973256344133 5.376233421511262e-09 8.269521883653342 -0.1888096250818837 ASS(ph)ESQIFELNK ddPTM_PC-9_Lapatinib_30min_R1 1 ASSESQIFELNK 12 0 Q9BV36;Q9BV36-4;H7C371 Q9BV36 MLPH Melanophilin 1 AS(0.091)S(0.899)ES(0.01)QIFELNK 92.039 0.021318 0.0 10200.0 10602.0 13529.0 10394.0 12401.0 12318.0 11432.0 14853.0 18106.0 15463.0 True False 10054.54612954909 10577.451720384932 12416.69784345024 11158.40943336756 11671.597561304066 11791.187854660478 12023.893022794398 15543.124603542337 16066.711615367454 18135.758946847636 0.5544044866838492 0.583237335221833 0.6846527834782737 0.6152711593747291 0.6435681900885006 0.6501623609587084 0.6629936501711385 0.8570429640742467 0.8859133859495952 1.0 14.146549500150872 -7.96933618552847 1.0800074554023136 0.9920755181848034 0.6147429842657651 0.9238328501578288 0.03869945939744121 0.12535167825823315 0.267509019219079 0.035857673035417044 0.013024275051268854 1.0731583633598383e-08 7.96933618552847 -0.3773325339190383 ASS(ph)FADMMGILK ddPTM_PC-9_AZD4547_30min_R2 2 ASSFADMMGILK 12 0 E9PPF9;E9PLD2;Q9H019-3;Q9H019 E9PPF9 MTFR1L Mitochondrial fission regulator 1-like 1 AS(0.017)S(0.983)FADMMGILK;AS(0.011)S(0.989)FADMMGILK 91.09299999999999 0.005804600000000001 36492000.0 214272.0 216513.0 297008.0 393910.0 336747.0 317369.0 273148.0 317246.0 268796.0 284725.0 True False 282406.03886552947 286496.59310751985 293069.4798584201 303100.13534883317 289995.491726332 297523.86625936365 297457.6428422093 268222.92028784 283004.0078020903 274756.86441354547 1.0278397938057373 1.0427276993389492 1.066650256341955 1.1031576444715403 1.0554622260132158 1.082862358669048 1.0826213331452792 0.9762191778551126 1.030016150483257 1.0 18.067795999766624 -7.755876494961672 24.999868421919842 1.002338244631989 1.0667240081631453 0.608141506186828 0.02347118343685042 90.92157263132668 408611.6035374513 0.011826051832220977 0.006588844169644065 1.7543793428145487e-08 7.755876494961672 0.06438576353115621 ASS(ph)FADMMGILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSFADMMGILK 12 0 E9PPF9;E9PLD2;Q9H019-3;Q9H019 E9PPF9 MTFR1L Mitochondrial fission regulator 1-like 1 AS(0.062)S(0.938)FADMMGILK 73.273 0.020297 4753000.0 58389.0 54147.0 61472.0 77792.0 75588.0 67821.0 70877.0 63670.0 67517.0 54005.0 True False 68273.10446468263 59522.35631494358 62937.725613858216 73433.56644506681 60777.074012998164 64264.34736795293 64163.01745495707 61998.72996394134 68504.30839538533 63795.678996655224 1.0701838359344393 0.9330154839807302 0.9865515439871407 1.1510742984476565 0.9526832376246779 1.007346396788445 1.0057580460632938 0.9718327469669521 1.0738079674483436 1.0 15.9611710903545 -11.271264496427065 2.6997801384026814 0.9971389445885246 1.013677130013473 0.004218026589443369 0.062050627173133456 26170474.564350955 612744.6467516639 464590.48056473833 0.01500925796112568 5.3547044301652965e-12 11.271264496427065 0.01653818542494845 ASS(ph)FADMMGILK ddPTM_PC-9_Lapatinib_30min_R1 1 ASSFADMMGILK 12 0 E9PPF9;E9PLD2;Q9H019-3;Q9H019 E9PPF9 MTFR1L Mitochondrial fission regulator 1-like 1 AS(0.047)S(0.953)FADMMGILK 60.08 0.036733 8248000.0 105680.0 99924.0 100520.0 86255.0 91192.0 90746.0 95121.0 82271.0 93345.0 70756.0 True False 104172.98382066129 99692.63211731237 92255.63361842095 92598.4804382452 85828.26585037015 86865.00511925797 100045.89994937256 86093.61100505177 82831.50313357325 82986.08032355635 1.255306714264595 1.2013175188973677 1.111700097880552 1.1158314753174368 1.034248942903826 1.0467418726198177 1.2055744717584116 1.0374464087155268 0.9981373118313286 1.0 16.340581745740373 -1.5228787452803376 0.37571662664967326 1.0427961472387026 4.123174429100026 0.6136576057012744 0.05467065912823721 49.63442190467273 0.6811867212785296 0.044959122125035104 110.9023158096085 0.029999999999999995 1.5228787452803376 3.0803782818613237 ASS(ph)FSGISILTR ddPTM_PC-9_AZD4547_30min_R2 2 ASSFSGISILTR 12 0 Q9Y2K5-2;H7C0E9;A0A0U1RRA6;B5MCU0;B5MCG9;Q9Y2K5;H0YIX9;Q9Y2K5-3 Q9Y2K5-2 R3HDM2 R3H domain-containing protein 2 1 AS(0.004)S(0.995)FSGISILTR;AS(0.002)S(0.998)FSGISILTR 184.96 0.00045539 60091000.0 92244.0 110588.0 114968.0 182725.0 170113.0 140862.0 102849.0 169823.0 112066.0 128723.0 True False 121575.67320560743 146333.4083337925 113443.44920124313 140600.57432310804 146495.74631412193 132053.87687211568 112002.36175508637 143580.7574943164 117989.57997272653 124216.44695023216 0.9787405467676694 1.1780517952861878 0.913272372431444 1.1318998230519366 1.1793586913077305 1.0630949452693943 0.9016709502241728 1.1558916795602971 0.9498708332882806 1.0 16.92249668151061 -8.297934739583974 24.96743730812186 0.9749353807305282 1.0624430663038122 0.11288050097960856 0.09846527803916169 1495.1337859937753 1022847.6235466686 0.09209079949378676 0.023781257160391773 5.035762743316514e-09 8.297934739583974 0.08750768557328403 ASS(ph)FSGISILTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASSFSGISILTR 12 0 Q9Y2K5-2;H7C0E9;A0A0U1RRA6;B5MCU0;B5MCG9;Q9Y2K5;H0YIX9;Q9Y2K5-3 Q9Y2K5-2 R3HDM2 R3H domain-containing protein 2 1 AS(0.006)S(0.994)FSGISILTR;AS(0.014)S(0.664)FS(0.321)GIS(0.001)ILTR;AS(0.082)S(0.897)FS(0.021)GISILTR 154.67 6.212399999999999e-05 45106600.0 104082.0 92304.0 99811.0 113899.0 121022.0 102596.0 94623.0 87764.0 83202.0 77221.0 True False 121701.02688679563 101467.3311041158 102190.87277532519 107517.60829554035 97308.60786369625 97215.68515006414 85659.62442880489 85460.2879936444 84418.67184728054 91220.55601890053 1.3341403757896375 1.1123296714294548 1.1202614546018734 1.178655480605305 1.066739911599906 1.0657212517968147 0.9390386133039637 0.936853399314266 0.9254347433465471 1.0 16.477071343466513 -6.327033802061735 0.5857093220852967 0.9302197263182398 1.2470343779954431 0.756760583683512 0.05970646643623728 0.4987303643774208 0.35936663645403716 0.04486605440395287 0.08336588148263248 4.709406706580514e-07 6.327033802061735 0.31681465167720335 ASS(ph)FSGISILTR ddPTM_PC-9_Lapatinib_30min_R1 4 ASSFSGISILTR 12 0 Q9Y2K5-2;H7C0E9;A0A0U1RRA6;B5MCU0;B5MCG9;Q9Y2K5;H0YIX9;Q9Y2K5-3 Q9Y2K5-2 R3HDM2 R3H domain-containing protein 2 1 AS(0.03)S(0.959)FS(0.011)GISILTR;AS(0.014)S(0.986)FSGISILTR;AS(0.001)S(0.981)FS(0.017)GISILTR;AS(0.005)S(0.897)FS(0.098)GISILTR 174.46 0.00014268 45825000.0 118797.8 111090.29999999999 145216.40000000002 123526.0 115174.20000000001 110156.5 91887.7 128018.40000000001 140855.6 169217.5 True False 117103.72158715183 110833.07723571779 133277.26814351435 132610.514110656 108399.87999718948 105445.36328234342 96645.19549603085 133966.6022181464 124990.95905277546 198466.5194068546 0.5900427031074709 0.5584472260961606 0.671535272255655 0.6681757432285372 0.5461872376316061 0.5313005115295107 0.4869596936796632 0.6750085738316197 0.6297835999055594 1.0 17.59853612482933 -9.089436327608462 1.2566209645366044 1.0000487206984017 0.5864387927944621 0.8062340736094875 0.0599887517238457 1.262631660104954 2.3798180697530658 0.06265281939614152 0.018682836526401694 8.138861767793673e-10 9.089436327608462 -0.4136099279039396 ASS(ph)FSGISVLTR ddPTM_PC-9_AZD4547_30min_R2 4 ASSFSGISVLTR 12 0 H7C207;Q15032-2;Q15032-4;Q15032;Q15032-3;H7C1X4;H7BZ47 H7C207 R3HDM1 R3H domain-containing protein 1 1 AS(0.35)S(0.634)FS(0.002)GIS(0.014)VLTR;AS(0.146)S(0.853)FSGIS(0.001)VLTR;AS(0.139)S(0.86)FS(0.001)GISVLTR;AS(0.006)S(0.991)FS(0.001)GIS(0.003)VLTR 168.82 6.291e-05 67789900.0 95612.3 98410.6 150672.0 198454.0 176103.0 147390.0 118537.3 157801.0 130945.0 135117.0 True False 126015.02254061468 130219.90192582857 148673.99083266393 152703.49638373576 151654.13820904796 138173.68000015014 129086.89006282255 133416.48135623906 137866.48537048406 130386.59495641408 0.9664722250223595 0.9987215477891632 1.140255184072895 1.1711594772053204 1.1631114246042182 1.0597230493390761 0.9900319132191006 1.0232377139754116 1.057367020103335 1.0 16.992436028177494 -7.0031889868530905 24.526764680978438 1.020350178261888 1.0926065128202038 0.20984502666582583 0.06391248961009814 182.43617735500436 1403142.499436279 0.025873185556836334 0.022362160929513177 9.926839797349336e-08 7.0031889868530905 0.07225633455831582 ASS(ph)FSGISVLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ASSFSGISVLTR 12 0 H7C207;Q15032-2;Q15032-4;Q15032;Q15032-3;H7C1X4;H7BZ47 H7C207 R3HDM1 R3H domain-containing protein 1 1 AS(0.054)S(0.842)FS(0.098)GIS(0.007)VLTR;AS(0.271)S(0.729)FSGISVLTR;AS(0.04)S(0.96)FSGISVLTR;AS(0.013)S(0.505)FS(0.025)GIS(0.458)VLTR 150.51 0.00017564 54690000.0 139187.0 153604.0 150134.0 161827.0 178623.0 146347.0 152353.0 127728.0 134319.0 118157.0 True False 162748.61003144074 168852.78998652875 153713.76394636603 152760.35784021244 143623.10540593465 138672.3056908306 137921.02089979924 124375.27533900276 136283.1612684177 139577.92876970262 1.166005338136008 1.2097384699348015 1.1012755763125481 1.094444939731555 1.0289814920731943 0.9935117028397359 0.9881291556300624 0.8910812507055929 0.9763947815365484 1.0 17.090711303004937 -6.066907180540199 0.7963041871421407 0.9517446815057192 1.201258879626808 0.8689984910617969 0.033164049212924686 0.23365490104468808 0.30261611886149214 0.016748768319536558 0.03713479086260841 8.572210349659557e-07 6.066907180540199 0.24951419812108877 ASS(ph)FSGISVLTR ddPTM_PC-9_Lapatinib_30min_R1 3 ASSFSGISVLTR 12 0 H7C207;Q15032-2;Q15032-4;Q15032;Q15032-3;H7C1X4;H7BZ47 H7C207 R3HDM1 R3H domain-containing protein 1 1 AS(0.328)S(0.672)FSGISVLTR;AS(0.007)S(0.992)FS(0.001)GISVLTR;AS(0.148)S(0.852)FSGISVLTR 190.35 0.00016521 40331400.0 138569.0 124722.0 138556.0 102155.0 111099.0 119326.0 112218.0 109055.0 123808.0 140154.0 True False 136592.98064955758 124433.2138718969 127164.46052162703 109667.81947909018 104564.37524903785 114222.70514249202 118028.09895310896 114122.09342485071 109863.43928396191 164379.4321565342 0.8309615069085023 0.7569877340457195 0.7736032352303764 0.6671626616562126 0.6361159293302824 0.6948722455356869 0.7180223061040503 0.6942601755441962 0.6683527120311613 1.0 17.326670268699075 -10.560832850789913 4.827308384147891 1.000005490439328 0.713589406082217 0.7066284233657179 0.05496255739831861 84376230.88950668 21.018938374272633 6095.854983346617 0.014437354104299017 2.7489519531799712e-11 10.560832850789913 -0.2864160843571111 ASS(ph)GDQGSPPCFLR ddPTM_PC-9_AZD4547_30min_R2 1 ASSGDQGSPPCFLR 14 0 A6NN50;O75147-2;O75147-1;O75147-4;O75147 A6NN50 OBSL1 Obscurin-like protein 1 1 AS(0.009)S(0.949)GDQGS(0.043)PPCFLR 111.72 0.00037289 21311000.0 66630.0 67758.0 106020.0 137570.0 118260.0 95885.0 77875.0 102340.0 72297.0 96350.0 True False 87816.9540099044 89659.44842009168 104614.10552776263 105855.36193531242 101841.64031619027 89889.29579221373 84805.72413613489 86525.70453924565 76118.47182274927 92976.81582665739 0.9445037800996234 0.9643204881015662 1.1251633495687934 1.1385135207540913 1.0953444620652544 0.9667925814947254 0.9121168904541064 0.9306159150530713 0.8186822827387614 1.0 16.50458339833221 -6.962345775332758 3.927964711825892 0.9117995727605119 1.0568927408644408 0.4553414494038186 0.07145034390116571 0.2141533956529162 7.146258808480099 0.029125688249708386 0.02465070487064361 1.0905717024568249e-07 6.962345775332758 0.14509316810392892 ASS(ph)GDQGSPPCFLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASSGDQGSPPCFLR 14 0 A6NN50;O75147-2;O75147-1;O75147-4;O75147 A6NN50 OBSL1 Obscurin-like protein 1 1 AS(0.034)S(0.764)GDQGS(0.202)PPCFLR;AS(0.06)S(0.823)GDQGS(0.117)PPCFLR 112.08 0.00033797 18496800.0 67046.0 64730.0 73518.0 86106.0 94158.0 72566.0 74875.0 72386.0 72986.0 61123.0 True False 78395.56358113897 71155.96661433327 75270.94793856758 81281.75997941861 75708.41581885872 68760.5112148579 67782.29795194365 70485.94419930672 74053.28217405359 72204.11605059833 1.085749232442675 0.985483522358607 1.0424744745274648 1.1257219730030206 1.0485332410385675 0.9523073610744399 0.9387594732749583 0.9762039625263528 1.0256102591458833 1.0 16.139793460935124 -6.709738928771784 7.407853271073186 0.9746705495692157 1.0569552317585666 0.4935159742692673 0.03994652038004539 0.2025795509555106 24.116457011144657 0.014050530590223632 0.013957252279096255 1.9510170792177208e-07 6.709738928771784 0.08228468218935092 ASS(ph)HS(ph)SQTQGGGSVTK ddPTM_PC-9_AZD4547_30min_R2 3 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 AS(0.011)S(0.989)HS(0.963)S(0.034)QT(0.003)QGGGSVTK;AS(0.05)S(0.95)HS(0.963)S(0.037)QTQGGGSVTK;AS(0.004)S(0.996)HS(0.747)S(0.224)QT(0.029)QGGGSVTK 163.9 5.0739999999999996e-12 79871000.0 77072.0 72704.4 183120.0 277591.0 231532.0 208815.0 147148.0 221435.0 177125.0 215901.0 True False 101579.29280281196 96204.67548796776 180691.7091515177 213596.68368819763 199387.77833323248 195757.76503990285 160243.88693655195 187217.30882008938 186487.46589214556 208342.3717051498 0.4875594530841233 0.4617624091565901 0.8672825775797356 1.0252196033866978 0.9570198164750182 0.9395965085630449 0.7691372889012333 0.8986040971302899 0.8951010030550399 1.0 17.668596752280855 -5.2921195724969365 4.84322110339633 0.9186216558224752 0.47018354276406077 0.8769718889562719 0.06674089870514813 0.05908414570633036 3.6735546463462305 0.018801872463223422 0.04357595425816711 5.103644641003477e-06 5.2921195724969365 -0.44843811305841447 ASS(ph)HS(ph)SQTQGGGSVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 AS(0.002)S(0.998)HS(0.997)S(0.003)QTQGGGSVTK;AS(0.017)S(0.983)HS(0.908)S(0.092)QTQGGGSVTK 242.19 2.8456999999999993e-109 18792000.0 44970.9 67015.0 103624.0 113509.0 135916.0 115896.0 119663.0 105029.0 114410.0 85421.0 True False 52583.58515423792 73667.80631329436 106094.78915620837 107149.45873114308 109284.23548116989 109818.20973675241 108327.65435490383 102272.10003742417 116083.02980754491 100907.15110773593 0.5211086090231186 0.730055357866968 1.0514100139734768 1.0618618953650014 1.0830177473199096 1.0883094858113909 1.0735379323041756 1.0135267809536206 1.1503944817905531 1.0 16.622668893698624 -5.073401199805397 2.176870674018428 1.0717735879088874 0.5025100699807405 0.9521940801446936 0.04069593832776422 0.06896115843833395 0.5508162446711437 0.010590577200539186 0.060059327949943384 8.444983399295554e-06 5.073401199805397 -0.5692635179281469 ASS(ph)HS(ph)SQTQGGGSVTK ddPTM_PC-9_Lapatinib_30min_R1 3 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 AS(0.054)S(0.944)HS(0.643)S(0.358)QT(0.001)QGGGSVTK;AS(0.042)S(0.958)HS(0.961)S(0.038)QT(0.001)QGGGSVTK;AS(0.036)S(0.964)HS(0.529)S(0.356)QT(0.115)QGGGSVTK 161.48 2.131e-06 36272200.0 116335.0 98364.0 190496.0 116407.0 167089.0 184384.0 123542.0 170794.0 214256.0 132467.0 True False 114676.04156677375 98136.24420146628 174834.15421582508 124967.95910236867 157261.15352961325 176498.32614009714 129938.40026435134 178729.71275415143 190124.23306429738 155363.7444488178 0.7381132707222566 0.6316547309645705 1.1253214502268998 0.8043572813317295 1.0122126889225467 1.1360329063016488 0.8363495661444845 1.150395244323113 1.2237361666249675 1.0 17.245290351371445 -4.170169668571081 0.4407165300861685 1.090319996386305 0.08478983386511764 0.44574708846855493 0.14216910625770807 7.8612040978286375 0.7908308162253456 0.09838999170922418 4.613908796373813 6.758188973693113e-05 4.170169668571081 -1.0055301625211874 ASS(ph)HSS(ph)QTQGGGSVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 AS(0.026)S(0.974)HS(0.292)S(0.706)QT(0.001)QGGGSVTK;AS(0.016)S(0.984)HS(0.109)S(0.877)QT(0.014)QGGGSVTK 163.02 0.00025558 12578800.0 24420.0 29370.0 45201.0 48410.0 58713.0 52287.0 53120.0 46091.0 43816.0 35505.0 True False 28553.823683014798 32285.659500432 46278.76326574711 45697.74464733758 47208.609124797054 49544.977673997106 48088.08904450413 44881.16008745126 44456.726108271956 41941.77544257466 0.6807967326540523 0.7697733145473656 1.1034049650356483 1.0895519840333292 1.1255748862952542 1.181279932744681 1.1465439537805167 1.0700825039917805 1.0599629042681011 1.0 15.356100313181932 -5.2048198574680296 3.5120549807077857 1.1069879433594842 0.6977760269523563 0.903804623699401 0.04875133341832144 0.06404941602264759 1.5807944390290298 0.013182815046304495 0.03998408909554277 6.239936103086946e-06 5.2048198574680296 -0.40921191640712795 ASS(ph)HSS(ph)QTQGGGSVTK ddPTM_PC-9_Lapatinib_30min_R1 4 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 AS(0.145)S(0.855)HS(0.412)S(0.546)QT(0.042)QGGGSVTK;AS(0.096)S(0.902)HS(0.126)S(0.501)QT(0.373)QGGGS(0.002)VTK;AS(0.071)S(0.929)HS(0.021)S(0.848)QT(0.131)QGGGSVTK;AS(0.074)S(0.926)HS(0.179)S(0.817)QT(0.004)QGGGSVTK 159.04 0.00016897 36025100.0 108344.0 92810.0 165790.0 104803.0 147199.0 175019.0 110372.0 134680.0 194127.0 112137.0 True False 106798.9946921439 92595.10414722962 152159.38616790684 112510.56223255924 138541.04422436882 167533.84535921604 116086.52210565635 140937.7244735123 172262.37301206446 131519.73103683972 0.812037812503043 0.7040396404193755 1.1569320053223482 0.8554652700821305 1.0533860062834404 1.2738305046585632 0.882654801606457 1.071608977317894 1.309783495252225 1.0 17.004919728202452 -5.127510784532776 0.8083791901603207 1.0974890200311234 0.6391726505759256 0.3630508907539044 0.15136469000015926 1.8188679970647799 1.281242395941897 0.060134392213634424 0.6827050580303593 7.455713575429983e-06 5.127510784532776 -0.4583163694551977 ASS(ph)HSSQT(ph)QGGGSVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 AS(0.075)S(0.892)HS(0.179)S(0.319)QT(0.533)QGGGS(0.001)VTK 125.41 0.0031777 0.0 10446.0 10826.0 17996.0 20127.0 24322.0 23060.0 22948.0 18006.0 18905.0 15481.0 True False 12214.301482095518 11900.733733458528 18425.09289021005 18999.34944261442 19556.278696937883 21850.693005190085 20774.19931086749 17533.361578934 19181.44986025381 18287.582752471437 0.6679013649545805 0.6507548807591986 1.007519317320384 1.038920763874427 1.0693747206308604 1.1948376830851042 1.1359729490798889 0.9587577437791494 1.0488783629789222 1.0 14.158576772214513 -5.310029861068578 3.6050373262980475 1.0682770764475884 0.650447740384999 0.865453515074183 0.06289725942685151 0.07842232500715841 2.087863996097871 0.018481957713566952 0.04608074267775212 4.897451444848522e-06 5.310029861068578 -0.41782933606258943 ASS(ph)HSSQTQGGGSVTK ddPTM_PC-9_AZD4547_30min_R2 5 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 AS(0.028)S(0.862)HS(0.103)S(0.005)QT(0.002)QGGGSVTK;AS(0.152)S(0.812)HS(0.03)S(0.006)QTQGGGSVTK;AS(0.017)S(0.733)HS(0.227)S(0.024)QTQGGGSVTK;AS(0.009)S(0.786)HS(0.195)S(0.009)QT(0.001)QGGGSVTK;AS(0.12)S(0.627)HS(0.212)S(0.041)QTQGGGSVTK 155.92 2.5966999999999997e-05 17212000.0 20603.1 19563.09 75552.0 161027.0 104722.0 84898.0 44287.1 103166.0 64558.0 88680.0 True False 27154.457228897783 25886.476265424215 74550.13111520009 123904.71299235 90183.15793330007 79589.31463907156 48228.566104519115 87224.06521883761 67970.40408223095 85575.3401920911 0.3173163807230463 0.3024992504536564 0.8711637131427966 1.447902079199696 1.0538451583232482 0.9300496435119895 0.5635801855564977 1.019266356675248 0.7942755930582067 1.0 16.384907502016432 -5.295518976060894 4.8313613851955575 0.9705235282789321 0.303223242118093 0.6077800424044362 0.2097499469003368 0.12757942112088477 7.669403744344821 0.059876359808588346 0.13803850828908354 5.063852230470849e-06 5.295518976060894 -0.667300286160839 ASS(ph)HSSQTQGGGSVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 AS(0.099)S(0.759)HS(0.118)S(0.023)QT(0.001)QGGGSVTK;AS(0.007)S(0.928)HS(0.053)S(0.007)QT(0.005)QGGGSVTK;AS(0.004)S(0.996)HSSQTQGGGSVTK;AS(0.262)S(0.328)HS(0.328)S(0.079)QT(0.002)QGGGSVTK;AS(0.149)S(0.821)HS(0.028)S(0.001)QTQGGGSVTK 232.62 2.3318999999999998e-30 11217800.0 25386.3 34927.4 69462.2 73134.7 98360.0 102073.0 85264.5 90990.7 91778.9 64574.3 True False 29683.699187719834 38394.76144485494 71118.44228486028 69037.19986489665 79087.06408316788 96720.11219075322 77187.6292984775 88602.29053761599 93120.99278388 76281.10942012243 0.3891356511903257 0.5033324991826439 0.9323205027495277 0.9050366517963242 1.0367843976624866 1.2679431765741875 1.011883936734092 1.161523360254686 1.2207608606085025 1.0 16.219038205676124 -5.1334344163351195 0.8777959870550632 1.133919647857223 0.13951842395074052 0.8804907481447124 0.09460529041534183 0.44035278930768623 0.3783228656989324 0.03486978113863505 0.379919674021807 7.354710520215356e-06 5.1334344163351195 -0.9944012239064826 down ASS(ph)HSSQTQGGGSVTK ddPTM_PC-9_Lapatinib_30min_R1 2 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 AS(0.083)S(0.653)HS(0.22)S(0.044)QTQGGGSVTK;AS(0.167)S(0.296)HS(0.232)S(0.294)QT(0.012)QGGGSVTK 81.428 0.0040948 21446700.0 39700.0 27512.0 107671.0 36301.0 64288.0 105696.0 47887.0 64305.0 154578.0 47871.0 True False 39133.87071991165 27448.29765433224 98818.70600207943 38970.696636586086 60506.706235070975 101175.62846941012 50366.35454710946 67292.84505694418 137167.79786149727 56145.43856590206 0.6970089061460856 0.48887849762032115 1.7600486972078522 0.6941026311664356 1.0776780408269457 1.8020275743443126 0.8970693939453468 1.1985451850724718 2.4430799966143866 1.0 15.77688119780015 -4.760412156566435 0.4593337916307959 1.4742055620614087 1.4028757141501795e-09 0.21600481852695685 0.5149515186133814 8.24558966116892 1.3322426542820869 0.3619079665193911 6.696576017039602 1.7361523936617746e-05 4.760412156566435 -1.474205560658533 ASS(ph)HSSQTQGGGSVTKK ddPTM_PC-9_AZD4547_30min_R2 2 ASSHSSQTQGGGSVTKK 17 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 AS(0.445)S(0.524)HS(0.027)S(0.003)QT(0.001)QGGGSVTKK;AS(0.068)S(0.502)HS(0.209)S(0.209)QT(0.012)QGGGSVTKK 59.261 0.018084 21302000.0 2423.17 1318.9 31138.0 88398.0 61204.0 37798.0 13942.199999999999 41365.0 18797.4 36934.0 True False 3193.687654932912 1745.2086325047817 30725.08977479221 68019.20683548566 52706.881057940926 35434.48508477963 15183.028790379749 34972.98972313761 19790.992188347333 35640.95190183465 0.08960724909169765 0.04896638668101751 0.8620726477625479 1.9084565143722863 1.4788292187905283 0.9942070341548765 0.425999530882288 0.9812585763551771 0.555287980042098 1.0 15.121248248556224 -5.313511398986431 4.603828924171518 1.0590033393540896 0.06141857262183712 0.4837507594117961 0.39748958672061585 0.17868258338190285 8.24758214550989 0.11764871795949157 0.2678835922695021 4.858347789985124e-06 5.313511398986431 -0.9975847667322525 ASS(ph)HSSQTQGGGSVTKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSHSSQTQGGGSVTKK 17 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 AS(0.187)S(0.632)HS(0.157)S(0.021)QT(0.002)QGGGSVTKK 47.537 0.045963 4379100.0 973.93 2252.4 7619.5 5670.2 10658.0 12150.0 8213.4 6820.1 10982.0 6685.9 True False 1138.7971130056753 2476.003386406983 7801.177777114665 5352.517077036428 8569.641409093172 11512.832611147418 7435.367292133472 6641.079601493264 11142.590974097182 7898.00074444472 0.14418802300147668 0.31349748708855835 0.987740825752877 0.6777053143229027 1.085039326581587 1.457689481638159 0.9414239796524894 0.8408557831758187 1.410811588228152 1.0 12.947271788444985 -5.220630563706746 1.095100988868444 1.1030089183060139 7.251165499503373e-16 0.6974760023500756 0.21944150254861278 0.5388136379367077 0.8629318629560631 0.07459774500484503 0.5803348712762622 6.016853486063661e-06 5.220630563706746 -1.1030089183060132 ASS(ph)KGGGGYTCQSGSGWDEFTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASSKGGGGYTCQSGSGWDEFTK 22 1 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 AS(0.063)S(0.831)KGGGGY(0.055)T(0.047)CQS(0.002)GS(0.001)GWDEFTK;AS(0.037)S(0.655)KGGGGY(0.099)T(0.042)CQS(0.065)GS(0.102)GWDEFTK 89.434 0.00033808 5674500.0 16765.3 8936.6 16892.9 20572.0 29546.4 31287.4 34894.4 33995.1 31397.6 28360.1 True False 19603.33416023129 9823.76658806812 17295.690802680016 19419.417535323886 23756.995020607104 29646.633665680143 31588.949818421403 33102.76464578579 31856.730501576556 33501.56163157193 0.5851468769072864 0.29323309450775525 0.5162652115410801 0.5796570843140336 0.709130973710147 0.8849328873595285 0.9429097713657599 0.9880961672720858 0.9509028519898821 1.0 15.03194072603372 -6.461003600465689 1.0857432509086276 0.9821833633693019 0.4343706113563954 0.9087282660910536 0.06993468472233151 0.12789434217325193 0.3195472706302649 0.031533583852463076 0.038648290672167726 3.4593650986958766e-07 6.461003600465689 -0.5478127520129066 ASS(ph)KGGGGYTCQSGSGWDEFTK ddPTM_PC-9_Lapatinib_30min_R1 2 ASSKGGGGYTCQSGSGWDEFTK 22 1 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 AS(0.173)S(0.594)KGGGGY(0.215)T(0.016)CQS(0.002)GSGWDEFTK;AS(0.14)S(0.521)KGGGGY(0.239)T(0.089)CQS(0.01)GS(0.001)GWDEFTK 54.855 0.0064979 7429800.0 11215.9 13646.3 14447.0 14074.3 19516.8 15836.599999999999 16532.7 14127.8 19533.7 13733.599999999999 True False 11055.959209255845 13614.702830776172 13259.223427032719 15109.370972488452 18368.860195505127 15159.305534917687 17388.68231087762 14784.22916406957 17333.609007019968 16107.434461128283 0.6863885888182223 0.8452434100310782 0.8231741348400896 0.9380370914406987 1.1403963952070886 0.941137185533879 1.0795438809849789 0.9178512692227943 1.07612475772295 1.0 13.975439104198747 -5.774670506727371 2.2752986925237146 1.021656043088417 0.7740411426546809 0.6914299708823577 0.07220810026274596 0.16605686540064915 1.7541694597904212 0.020671591102810354 0.038446507264952204 1.6800781870139195e-06 5.774670506727371 -0.24761490043373602 ASS(ph)LDDLR ddPTM_PC-9_AZD4547_30min_R2 2 ASSLDDLR 8 0 Q96P11-5;Q96P11;Q96P11-2;Q96P11-4;Q96P11-3 Q96P11-5 NSUN5 Probable 28S rRNA (cytosine-C(5))-methyltransferase 1 AS(0.245)S(0.755)LDDLR;AS(0.103)S(0.897)LDDLR 135.55 0.0036637 10092000.0 87976.0 78140.0 120092.0 151466.0 136683.0 121618.0 110772.0 136770.0 109823.0 125745.0 True False 115950.53798552221 103397.22688901633 118499.5016132811 116547.85382637237 117706.92477031799 114013.20723426467 120630.49340620164 115635.33916193724 115628.01957190191 121342.70582379913 0.9555624888890574 0.8521091250359843 0.9765688082261276 0.9604850413968078 0.9700370860465183 0.9395967104922024 0.9941305708261385 0.9529648970400453 0.952904575408138 1.0 16.888727861969002 -5.289319269739518 24.914494702496953 0.9663313391016886 0.9038357870717701 0.43845148181913285 0.029127435956027507 510.02998939779036 455780.63777746184 0.006974689816867945 0.01452439625190312 5.136658934509763e-06 5.289319269739518 -0.06249555202991841 ASS(ph)LDDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSLDDLR 8 0 Q96P11-5;Q96P11;Q96P11-2;Q96P11-4;Q96P11-3 Q96P11-5 NSUN5 Probable 28S rRNA (cytosine-C(5))-methyltransferase 1 AS(0.09)S(0.91)LDDLR 82.645 0.039173 0.0 15452.0 21350.0 28255.0 24676.0 28579.0 28509.0 27819.0 29433.0 31926.0 18858.0 True False 18067.718409088644 23469.486902765537 28928.706357684212 23293.483720671407 22979.150106068093 27013.937852773804 25183.7829278814 28660.41493684129 32392.85735194197 22276.806120154146 0.8110551535815774 1.0535391283731808 1.2986020617880225 1.045638391564465 1.031528037822196 1.2126486044305027 1.130493428548416 1.286558530080836 1.4541068938350048 1.0 14.443254784358706 -7.115187251707677 1.29583039816765 1.2626330867617883 1.059767994323634 0.20851558712906915 0.15563628477784655 0.7114820096556194 2.387701241963489 0.09227042493972669 0.060543267424739276 7.67030702803677e-08 7.115187251707677 -0.20286509243815432 ASS(ph)LDDLR ddPTM_PC-9_Lapatinib_30min_R1 2 ASSLDDLR 8 0 Q96P11-5;Q96P11;Q96P11-2;Q96P11-4;Q96P11-3 Q96P11-5 NSUN5 Probable 28S rRNA (cytosine-C(5))-methyltransferase 1 AS(0.33)S(0.67)LDDLR;AS(0.043)S(0.957)LDDLR 117.53 0.0035428000000000005 10031700.0 146421.0 134488.0 148224.0 126601.0 151430.0 138229.0 115363.0 110307.0 155456.0 110897.0 True False 144333.00968967707 134176.6012989178 136037.59488118647 135911.65986855535 142523.1851228349 132317.26789753724 121335.93166450574 115432.26591550144 137946.9082557474 130065.39868903591 1.1096956695973583 1.0316087341546623 1.0459168714534837 1.0449486276784254 1.0957809421980356 1.0173133610568108 0.9328840174826141 0.8874940382221118 1.060596512570994 1.0 16.988877687229305 -7.025821841155312 4.994475261102551 0.9618301553045746 1.061387631439125 0.4679778492315898 0.04746720970598672 0.1637729450700588 10.95837997326644 0.017701000741565973 0.01425125722027439 9.422760632941608e-08 7.025821841155312 0.09955747613455046 ASS(ph)LEDLVLK ddPTM_PC-9_AZD4547_30min_R2 6 ASSLEDLVLK 10 0 Q15477 Q15477 SKIV2L Helicase SKI2W 1 AS(0.025)S(0.975)LEDLVLK;AS(0.002)S(0.998)LEDLVLK;ASS(1)LEDLVLK;AS(0.024)S(0.976)LEDLVLK;ASS(1)LEDLVLK;AS(0.12)S(0.88)LEDLVLK 211.37 1.4037000000000001e-05 85169000.0 1140458.0 1106060.0 1383379.0 1798074.0 1590914.0 1422540.0 1283754.0 1556426.0 1274829.0 1411287.0 True False 1503099.9209999582 1463572.2648178337 1365034.4905762183 1383555.819266374 1370043.0522745752 1333588.348920642 1398005.61903897 1315916.1248114156 1342213.8583250127 1361878.2716923337 1.1036962350035409 1.0746718669643875 1.0023175484545785 1.0159173899933822 1.005995235221791 0.9792272750364558 1.0265275892108496 0.966250914023466 0.9855608142254263 1.0 20.377166326511073 -5.071877855203661 1.4345293328414364 0.9948376429725394 1.1237725012593478 0.8278376863196804 0.016875190322657677 0.2768232919958811 0.7596154573205759 0.004984029117458225 0.044059222354689266 8.474657293346954e-06 5.071877855203661 0.1289348582868084 ASS(ph)LEDLVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 10 ASSLEDLVLK 10 0 Q15477 Q15477 SKIV2L Helicase SKI2W 1 AS(0.002)S(0.998)LEDLVLK;AS(0.033)S(0.967)LEDLVLK;AS(0.048)S(0.952)LEDLVLK;AS(0.04)S(0.96)LEDLVLK;AS(0.024)S(0.976)LEDLVLK;AS(0.001)S(0.999)LEDLVLK;AS(0.001)S(0.999)LEDLVLK;ASS(1)LEDLVLK;AS(0.105)S(0.895)LEDLVLK;AS(0.076)S(0.924)LEDLVLK 201.09 3.4118e-13 82681940.0 996051.4 995746.6 953941.9 1159451.0 1275767.4 1116575.0 1141074.0 983607.9 1013476.8 908190.2 True False 1164663.2291081084 1094597.7417879761 976687.4927408014 1094490.7194608578 1025789.9361429113 1058019.841382051 1032983.2100596497 957789.2348437177 1028296.9808902652 1072837.89403033 1.0855910623484955 1.0202825122776946 0.9103775119945471 1.0201827559885908 0.9561462564389167 0.9861879854069918 0.9628511593480742 0.892762308428155 0.9584830910728387 1.0 20.033000670445162 -4.973338345297232 3.836970303756418 0.9598884844156436 1.080371794713362 0.5414359248734499 0.03621693392234147 0.16317688687780707 5.154008323647683 0.0092487329956331 0.042041431208541855 1.0633143004159973e-05 4.973338345297232 0.12048331029771842 ASS(ph)LEDLVLK ddPTM_PC-9_Lapatinib_30min_R1 10 ASSLEDLVLK 10 0 Q15477 Q15477 SKIV2L Helicase SKI2W 1 ASS(1)LEDLVLK;AS(0.001)S(0.999)LEDLVLK;AS(0.147)S(0.853)LEDLVLK;AS(0.002)S(0.998)LEDLVLK;AS(0.002)S(0.998)LEDLVLK;AS(0.166)S(0.834)LEDLVLK;AS(0.146)S(0.854)LEDLVLK;AS(0.013)S(0.987)LEDLVLK;ASS(1)LEDLVLK;AS(0.046)S(0.954)LEDLVLK 222.18 1.1246e-08 78723400.0 1284222.9 1155724.7 1218404.2 1080966.3 1119385.7 1117226.5 986290.3 982530.0 1188370.2 833516.7999999999 True False 1265909.6459483642 1153048.6904646633 1118231.7098522217 1160464.1676998667 1053545.63392296 1069445.326977175 1037355.585778498 1028181.930702111 1054523.43398302 977589.0682886759 1.294930239107941 1.1794819805863206 1.1438668312952278 1.1870674553791032 1.0776978467724176 1.0939620354483899 1.0611366467041685 1.0517526883785646 1.0786980626011111 1.0 19.898868627009684 -1.5228787452803572 0.2429007403897477 1.0161442928880586 2.5879361353062036 0.880462711626208 0.028046364805376534 16.073647363672016 0.21591128253264882 0.03727024053330248 10.224376219340003 0.029999999999998646 1.5228787452803572 1.571791842418145 ASS(ph)LGEIDESSELR ddPTM_PC-9_AZD4547_30min_R2 3 ASSLGEIDESSELR 14 0 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 AS(0.08)S(0.92)LGEIDESSELR;AS(0.071)S(0.929)LGEIDESSELR;AS(0.098)S(0.902)LGEIDESSELR 230.57 6.0738e-21 113447800.0 66131.7 66552.8 95255.7 141909.0 117996.09999999999 90229.9 86002.4 120810.0 101395.5 106480.4 True False 87160.20497518807 88064.69108906241 93992.54717903133 109194.07252219421 101614.3782759444 84587.81008918872 93656.44699127485 102141.59043762258 106755.05912698414 102752.5536061112 0.848253419660066 0.8570559854565479 0.9147465817671039 1.0626896236640089 0.9889231431217772 0.8232185684985045 0.9114756150031548 0.9940540342108608 1.0389528569403348 1.0 16.648814722641525 -5.46094951608978 4.477610295426984 0.9671514361536074 0.8562454838781558 0.36366018851892723 0.06381231506987073 0.27133932537125915 10.80800477750328 0.01887653835059082 0.039994368411899 3.4597959336723217e-06 5.46094951608978 -0.11090595227545164 ASS(ph)LGEIDESSELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 ASSLGEIDESSELR 14 0 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 AS(0.005)S(0.995)LGEIDESSELR;AS(0.001)S(0.999)LGEIDESSELR;AS(0.001)S(0.999)LGEIDESSELR;AS(0.002)S(0.998)LGEIDESSELR;AS(0.032)S(0.968)LGEIDESSELR;AS(0.004)S(0.996)LGEIDESSELR;AS(0.059)S(0.941)LGEIDESSELR 296.97 1.0208999999999998e-98 302715800.0 115914.90000000001 125647.29999999999 159515.5 175647.0 213238.6 194244.1 208138.0 201613.4 200497.4 162327.8 True False 135537.0031463675 138120.73356992268 163318.9544859026 165806.06804525753 171456.02707609814 184057.59744880503 188421.66185137452 196321.26187705487 203429.29517118452 191756.5451538423 0.7068181325316899 0.7202921467901462 0.8516995044673712 0.8646696670105042 0.8941338974299027 0.9598504045905678 0.9826087641504373 1.0238047505473693 1.0608727592999625 1.0 17.54891629597121 -5.546691591552905 0.4595169462523512 1.0414694311716846 0.5843170924076166 0.9500127567923828 0.025922009247419667 0.5159510884476586 0.1402782029271498 0.021013801345482357 0.11981924428448791 2.839935054617301e-06 5.546691591552905 -0.4571523387640679 ASS(ph)LGEIDESSELR ddPTM_PC-9_Lapatinib_30min_R1 3 ASSLGEIDESSELR 14 0 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 AS(0.361)S(0.639)LGEIDESSELR;AS(0.049)S(0.951)LGEIDESSELR;AS(0.028)S(0.972)LGEIDESSELR 238.88 3.9616e-27 91329000.0 80994.0 68449.5 92511.1 68011.0 86496.0 92202.6 76869.5 66439.0 90346.6 81483.5 True False 79839.01070751963 68291.00938827486 84905.19446117319 73012.75581804512 81408.47533767886 88259.30973275838 80849.4265846479 69525.99848749393 80170.81451612501 95567.81440506093 0.8354173547291215 0.7145816801755636 0.888428755954441 0.7639889671284418 0.8518398777294603 0.9235254597188369 0.8459901179906695 0.7275043268522429 0.8388892747544037 1.0 16.544237204696742 -12.110350045688161 1.9285650241536214 3.442445161931143 0.8201869343400564 0.41556035812198056 0.06362860529212039 2353139.471839117 116804.16000364006 25147993.868700966 0.016244967581301485 7.756217057806346e-13 12.110350045688161 -2.6222582275910864 ASS(ph)LNENVDHSALLK ddPTM_PC-9_AZD4547_30min_R2 1 ASSLNENVDHSALLK 15 0 Q96SB3 Q96SB3 PPP1R9B Neurabin-2 1 AS(0.002)S(0.998)LNENVDHSALLK 163.02 0.00033081 3797300.0 16664.0 15887.0 22529.0 27466.0 24368.0 21364.0 25459.0 29957.0 26665.0 24627.0 True False 21962.805367267672 21022.162062782216 22230.250739812887 21134.13804546989 20984.923822297646 20028.105702715267 27724.80167938187 25327.833993376844 28074.457462323586 23764.816225875413 0.9241731624818672 0.8845918210759416 0.935426999667194 0.889303659855732 0.8830248726875916 0.8427629110343563 1.1666322775597473 1.0657702442402899 1.1813454476351382 1.0 14.536539624823474 -7.26040758023365 24.99915821076175 1.108917850462197 0.8940998893572415 0.7922205269130606 0.05271187716381381 38.09258824326225 922947.8896715401 0.019610633223287172 0.014301726764499116 5.4902537817960004e-08 7.26040758023365 -0.21481796110495555 ASS(ph)LNENVDHSALLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSLNENVDHSALLK 15 0 Q96SB3 Q96SB3 PPP1R9B Neurabin-2 1 AS(0.164)S(0.836)LNENVDHSALLK 139.67 2.0926e-06 0.0 12317.0 10915.0 12872.0 11346.0 17952.0 16766.0 13952.0 18074.0 14429.0 11120.0 True False 14402.024828161077 11998.569065278021 13178.91729733184 10710.320404228307 14434.434469510285 15886.761445143831 12630.365556267354 17599.576650985953 14639.996828013866 13135.967974128438 1.096380933367542 0.9134133920628805 1.0032695971311738 0.815343066100839 1.09884817760969 1.209409270518407 0.9615100753247208 1.33980051456038 1.1144969945760863 1.0 13.681234894449668 -6.497755345645784 22.19097067438698 1.1380677134227823 0.9572558210696044 0.31335437978813707 0.11836852019783833 200.6152838557507 177199.0579524202 0.035271557747471635 0.03975013107031071 3.1786642270316585e-07 6.497755345645784 -0.18081189235317796 ASS(ph)LNENVDHSALLK ddPTM_PC-9_Lapatinib_30min_R1 1 ASSLNENVDHSALLK 15 0 Q96SB3 Q96SB3 PPP1R9B Neurabin-2 1 AS(0.025)S(0.975)LNENVDHSALLK 155.79 3.2083e-14 0.0 20832.0 17752.0 18045.0 19770.0 29696.0 24821.0 24952.0 22904.0 27621.0 33427.0 True False 20534.931859879067 17710.896334679626 16561.40975571436 21223.951750786677 27949.339664582338 23759.46369057701 26243.89246892633 23968.203455162846 24510.032117975516 39204.81241132227 0.5237859996480589 0.45175312022573927 0.42243308249911327 0.5413608800907626 0.7129058384809571 0.6060343674470771 0.669404872891246 0.611358707795803 0.6251791708840587 1.0 15.258743136334147 -14.522878745278097 0.10304691088770948 2.3642819799819526 0.2992219995388942 0.8137429443559128 0.06663912972014592 81.063958520064 0.5623809768488173 23.588864877810884 1.1347767505525481 3.0000000000154745e-15 14.522878745278097 -2.0650599804430585 ASS(ph)LNFLNK ddPTM_PC-9_AZD4547_30min_R2 3 ASSLNFLNK 9 0 Q9H0B6;Q9H0B6-2;A8MZ87 Q9H0B6 KLC2 Kinesin light chain 2 1 AS(0.001)S(0.999)LNFLNK;AS(0.001)S(0.999)LNFLNK;AS(0.034)S(0.966)LNFLNK 141.88 0.00069293 749512700.0 294971.0 318039.0 392562.0 549499.0 425022.0 348186.0 359753.0 410331.0 322733.0 390339.0 True False 388765.6422220535 420838.8871583811 387356.3713845456 422820.49522492016 366015.0317137474 326413.8743777206 391770.3200660931 346923.77241834375 339792.00750752166 376673.3504199451 1.032102859914637 1.1172515567910415 1.0283614993008936 1.1225123698120045 0.9717040807524213 0.8665701303631083 1.040079739193964 0.9210202209197063 0.9020866677419435 1.0 18.52295444088638 -6.394707214357931 5.547057700708458 0.9442112595147034 1.0740839027893552 0.5672092207922501 0.053698861803416154 0.16334149524878305 6.7001204257961815 0.01615925344894578 0.018317263194093464 4.029886231311339e-07 6.394707214357931 0.12987264327465176 ASS(ph)LNFLNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ASSLNFLNK 9 0 Q9H0B6;Q9H0B6-2;A8MZ87 Q9H0B6 KLC2 Kinesin light chain 2 1 AS(0.008)S(0.992)LNFLNK;AS(0.039)S(0.961)LNFLNK;AS(0.011)S(0.989)LNFLNK;AS(0.02)S(0.98)LNFLNK 146.71 0.00042235 774945900.0 423622.0 495070.0 449397.0 575281.0 541684.0 479510.0 540394.0 517570.0 447975.0 357144.0 True False 495332.8376841161 544217.2777963517 460112.3288276136 543049.8706561656 435544.9087111293 454363.6514708885 489203.9682062468 503984.33591074595 454525.78688956413 421891.38004965085 1.1740766962951985 1.2899464258603832 1.0905942870258802 1.2871793460019403 1.0323626632520237 1.0769683216031012 1.1595495697226006 1.1945831551510577 1.0773526276741483 1.0 18.686512085609472 -1.5235487622881738 0.01910947673527975 2.1478931805123072e-08 2.591839802679824 0.33731050982344146 0.07729799712691918 4076.613188722041 6.0291063116361086 307.48739210375066 540.4852319712088 0.029953752548561557 1.5235487622881738 2.591839781200892 ASS(ph)LNFLNK ddPTM_PC-9_Lapatinib_30min_R1 3 ASSLNFLNK 9 0 Q9H0B6;Q9H0B6-2;A8MZ87 Q9H0B6 KLC2 Kinesin light chain 2 1 ASS(1)LNFLNK;ASS(1)LNFLNK;AS(0.122)S(0.878)LNFLNK 163.9 0.00032942 669657500.0 370831.0 334488.0 350642.0 279156.0 303066.0 282695.0 256109.0 267653.0 305478.0 244276.0 True False 365542.88193792413 333713.51358688204 321813.56827726186 299686.06347711635 285240.2537306812 270604.7938442315 269369.07086903846 280089.1354953153 271071.8508140518 286498.7811226898 1.2758968136111708 1.1647990692287555 1.1232633067972773 1.0460291045663446 0.9956072155452919 0.9445233685945357 0.9402101810467539 0.9776276687731191 0.9461535918296575 1.0 18.128169475645898 -5.31909708172064 0.785578387314861 0.9551895735154723 1.3271063820549995 0.953691625668236 0.022927312171287507 0.26425013951615856 0.20688402440302625 0.009790206814358405 0.07546187196957445 4.796262215235377e-06 5.31909708172064 0.37191680853952724 ASS(ph)LNVLNVGGK ddPTM_PC-9_AZD4547_30min_R2 5 ASSLNVLNVGGK 12 0 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;H0YJK1 Q07866-6 KLC1 Kinesin light chain 1 1 ASS(1)LNVLNVGGK;AS(0.165)S(0.835)LNVLNVGGK;AS(0.315)S(0.685)LNVLNVGGK;AS(0.133)S(0.867)LNVLNVGGK;AS(0.005)S(0.995)LNVLNVGGK 198.48 8.5593e-06 473204400.0 1324098.0 1264828.0 1649571.0 2274362.0 1794898.0 1656089.0 1706260.0 1948891.0 1493250.0 1777377.0 True False 1745133.6210506728 1673658.9159403744 1627696.6107294569 1750042.9794426213 1545707.394894715 1552533.4930305183 1858113.8345363985 1647734.6770099232 1572180.1464697064 1715151.572221453 1.0174806992657723 0.9758081694043299 0.9490103598373378 1.0203430459361542 0.9012074617362971 0.9051873421424131 1.0833525529931922 0.9606933309548776 0.9166421043671545 1.0 20.709904645914463 -10.660279417669305 21.070253074509814 0.9999999999993368 0.970140513615194 0.026351988185177033 0.054753053054430616 0.0 0.0 0.0533091657509803 0.012929371835579484 2.1863545081057477e-11 10.660279417669305 -0.02985948638414271 ASS(ph)LNVLNVGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ASSLNVLNVGGK 12 0 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;H0YJK1 Q07866-6 KLC1 Kinesin light chain 1 1 AS(0.09)S(0.91)LNVLNVGGK;AS(0.004)S(0.996)LNVLNVGGK;AS(0.047)S(0.953)LNVLNVGGK;AS(0.002)S(0.998)LNVLNVGGK;AS(0.003)S(0.997)LNVLNVGGK 191.01 0.00012958 900716000.0 624312.0 683365.0 728742.0 812009.0 823396.0 723822.0 771457.0 733295.0 680882.0 542441.0 True False 729995.6908759335 751204.9609980517 746117.9730494252 766514.768298696 662057.4645976436 685863.5001041939 698379.0080949944 714046.7832402776 690838.6111478092 640781.2593394071 1.1392275916878394 1.1723266716203318 1.1643879438961926 1.1962190796417953 1.03320353856817 1.0703551174565606 1.0898867560748668 1.1143378069084 1.07811925064726 1.0 19.28947242890399 -1.5228805601823108 0.06765675282173071 0.8723974212519224 1.6476703219305808 0.5696924087778025 0.039338980313308375 212.94190687835055 1.071036529544813 2.2218994332676396 15.831767587527699 0.029999874631275094 1.5228805601823108 0.7752729006786584 ASS(ph)LNVLNVGGK ddPTM_PC-9_Lapatinib_30min_R1 5 ASSLNVLNVGGK 12 0 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;H0YJK1 Q07866-6 KLC1 Kinesin light chain 1 1 AS(0.207)S(0.793)LNVLNVGGK;AS(0.023)S(0.977)LNVLNVGGK;AS(0.219)S(0.781)LNVLNVGGK;AS(0.007)S(0.993)LNVLNVGGK;AS(0.054)S(0.946)LNVLNVGGK 193.51 1.7878e-05 825642100.0 2475480.0 2413078.0 2411154.0 1953699.0 2315789.0 2207139.0 2110124.0 1975650.0 2249090.0 1659760.0 True False 2440179.2012525713 2407490.666150075 2212918.2254436016 2097380.5418088115 2179578.844036348 2112744.8100623065 2219375.8958039717 2067445.9114649165 1995773.8002323424 1946647.3045088123 1.253529180967011 1.2367369582429546 1.136784367829783 1.0774322276823705 1.1196578029250708 1.085324909740342 1.1401016972429814 1.0620546961312978 1.025236464566408 1.0 20.892560088139113 -1.5228787452803376 0.2570578424144631 1.02747174003489 2.6025753546033616 0.8180131940881875 0.033453897556099475 22.73024916190434 0.3123862000631767 0.04504004349451022 15.623820830912656 0.029999999999999995 1.5228787452803376 1.5751036145684716 ASS(ph)LPGSLQR ddPTM_PC-9_AZD4547_30min_R2 1 ASSLPGSLQR 10 0 E3W994;J3KR49;O75122;A0A0U1RQI6;B3KR06;E7ENG2;O75122-2;E7ERI8;E7EW49;O75122-3 E3W994;E7ERI8 CLASP2 CLIP-associating protein 2 1 AS(0.006)S(0.992)LPGS(0.002)LQR 83.081 0.014033000000000002 9199100.0 17966.0 19540.0 29141.0 35898.0 37400.0 33597.0 34356.0 34285.0 32920.0 35212.0 True False 23678.814283985314 25855.92287447377 28754.571299608833 27622.270718571282 32207.65557099194 31496.174278886218 37413.61744360907 28987.041040922835 34660.083992487984 33979.238597698655 0.6968612382500246 0.7609329679395741 0.8462394240215942 0.8129161175625073 0.9478627803382651 0.9269240741909793 1.1010728605950288 0.8530809469899678 1.0200370997964456 1.0 15.05236590471339 -5.633806463673816 0.6618314907903328 0.9898049028050655 0.662511593384149 0.7135200183276078 0.06356031466138695 0.7398476940440113 0.49685182969467023 0.03384435838246672 0.1578727771309676 2.323772117190436e-06 5.633806463673816 -0.3272933094209165 ASS(ph)LPGSLQR ddPTM_PC-9_Lapatinib_30min_R1 1 ASSLPGSLQR 10 0 E3W994;J3KR49;O75122;A0A0U1RQI6;B3KR06;E7ENG2;O75122-2;E7ERI8;E7EW49;O75122-3 E3W994;E7ERI8 CLASP2 CLIP-associating protein 2 1 AS(0.327)S(0.673)LPGSLQR 113.67 0.0031462 0.0 49347.0 44905.0 60592.0 47270.0 42998.0 41076.0 33669.0 38267.0 54041.0 31187.0 True False 48643.30273086849 44801.02523145497 55610.359651883875 50746.3934880974 40468.94217732054 39319.27523283276 35412.21607631777 40045.02452055171 47954.33350304169 36577.63139593465 1.3298647527044316 1.224820293761129 1.520337909525344 1.3873613886802278 1.1063849853825796 1.074954110812184 0.968138578821525 1.0947954526383694 1.3110289450937898 1.0 15.15867403517252 -6.276749321866405 8.108906486220443 1.0898628802864447 1.3667333840440818 0.6029055174307718 0.10854866549610218 0.1383573848596524 58.71426887529153 0.03467556510711348 0.04060865293100289 5.287503625089319e-07 6.276749321866405 0.2768705037576371 ASS(ph)MPATLLHSR ddPTM_PC-9_AZD4547_30min_R2 1 ASSMPATLLHSR 12 0 Q5T7N3 Q5T7N3 KANK4 KN motif and ankyrin repeat domain-containing protein 4 1 AS(0.243)S(0.757)MPATLLHSR 90.229 0.0084764 0.0 13541.0 15825.0 15727.0 31171.0 24786.0 21772.0 20510.0 20672.0 19281.0 20024.0 True False 17846.756329703043 20940.121775258292 15518.449704160741 23985.00753714929 21344.89173750286 20410.593398217414 22335.35026686523 17477.61739530281 20300.15429705835 19322.96585483125 0.9236033672978252 1.0836908750228273 0.8031090993353238 1.2412694675001148 1.1046384855131375 1.056286780795311 1.1558965862003427 0.9044997298348454 1.0505713485998205 1.0 14.238028927950097 -5.7558262739690385 24.999997299460166 1.0733670287139239 0.9514901556881786 0.25751453045909223 0.1053386214848599 214.97508051538364 957457.1669969549 0.02874056700941833 0.0480647283824737 1.7545822276545935e-06 5.7558262739690385 -0.12187687302574524 ASS(ph)PAES(ph)SPEDSGYMR ddPTM_PC-9_Lapatinib_30min_R1 1 ASSPAESSPEDSGYMR 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 2 AS(0.02)S(0.98)PAES(0.828)S(0.17)PEDS(0.002)GYMR 135.61 9.891e-05 3992100.0 11066.0 7936.6 11418.0 10089.0 7282.5 11788.0 8252.1 8966.5 11474.0 8571.4 True False 10908.19681074414 7918.22329032325 10479.256114754588 10830.97871591739 6854.157667945879 11283.854719170136 8679.353360164601 9383.116323817572 10181.677293423521 10052.955069327416 1.0850736659538203 0.7876513160277172 1.0424055456815737 1.077392531969411 0.6818052623012918 1.1224415747761889 0.8633633892034579 0.9333689705275229 1.0128044165330898 1.0 13.29533202395951 -10.719994840995456 5.338232579330417 1.0000025465106899 0.9508043708649777 0.007900079350279476 0.13515778740500967 3.820287461202506e-06 5.747747491498165e-07 0.1220499203951287 0.029599921833370176 1.9054833531550333e-11 10.719994840995456 -0.04919817564571216 ASS(ph)PAESSPEDSGYMR ddPTM_PC-9_AZD4547_30min_R2 1 ASSPAESSPEDSGYMR 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 AS(0.055)S(0.944)PAES(0.001)SPEDSGYMR 80.507 0.007051699999999999 6759100.0 8836.4 11761.0 15430.0 22568.0 19912.0 17612.0 11349.0 18083.0 12166.0 16588.0 True False 11646.191391462075 15562.513251109829 15225.388118217106 17365.296272124247 17147.562506138813 16510.718855842606 12359.039014073793 15288.687856001397 12809.069922618739 16007.25916899425 0.7275568708239898 0.9722159856856767 0.951155220108411 1.0848388277338878 1.0712366386466279 1.0314519607343866 0.7720896428048727 0.9551096595983958 0.8002038192415638 1.0 13.966438684167727 -7.240156054245701 24.808760740077382 0.8781098935411727 0.9815824156270851 0.1350080096832601 0.11172514713472752 1388.4462049245847 1618434.9731634536 0.043438599182601574 0.033612073221188005 5.7523320269687615e-08 7.240156054245701 0.1034725220859124 ASS(ph)PAESSPEDSGYMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSPAESSPEDSGYMR 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 AS(0.163)S(0.835)PAES(0.002)SPEDSGYMR 142.95 2.4425e-05 5138500.0 12038.0 16419.0 16838.0 17719.0 18043.0 14423.0 15888.0 11065.0 11362.0 11827.0 True False 14075.795638662252 18048.969810609233 17239.481778470596 16726.261875773074 14507.60367275925 13666.632489759602 14382.973620841141 10774.555474336597 11528.147755207814 13971.141477519515 1.0074907380553788 1.291875101232867 1.233935094438064 1.1972008087303911 1.038397878663167 0.9782044303072953 1.029477343993996 0.771200799281402 0.825140005471805 1.0 13.77016227693826 -6.7964623722722735 1.127081959175703 0.8720906940659825 1.1973047973928426 0.6133954790668055 0.09844832128262031 0.30360673757065004 0.8164880298307973 0.053209789939123474 0.04641931414610784 1.5978559629718298e-07 6.7964623722722735 0.32521410332686007 ASS(ph)PAESSPEDSGYMR ddPTM_PC-9_Lapatinib_30min_R1 4 ASSPAESSPEDSGYMR 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 AS(0.028)S(0.97)PAES(0.002)S(0.001)PEDSGYMR;AS(0.333)S(0.55)PAES(0.05)S(0.05)PEDS(0.003)GY(0.013)MR;AS(0.111)S(0.889)PAESSPEDSGYMR;ASS(1)PAESSPEDSGYMR 235.93 5.117499999999999e-37 15734400.0 57812.1 44145.8 50889.7 43688.6 39157.5 46153.0 46464.8 46237.5 50370.8 33470.7 True False 56987.68885255926 44043.58311240985 46705.74530592281 46901.60538489721 36854.33283660702 44179.14377789777 48870.51998998749 48385.86304829255 44697.51007596106 39256.065898095665 1.4516912876724044 1.12195611314547 1.1897714209866488 1.1947607156215934 0.9388188040104866 1.1254093543805908 1.244916393732624 1.232570354194351 1.1386140983151691 1.0 15.26062797788339 -4.759398213009851 24.965337891768723 1.1402093224253935 1.4516916914592781 0.5161853859181624 0.09257319089623488 46.26863400513563 565762.7492450756 0.023856448265855222 0.15190470156769623 1.7402105089628552e-05 4.759398213009851 0.3114823690338846 ASS(ph)PAQCVTPVQTVV ddPTM_PC-9_Lapatinib_30min_R1 1 ASSPAQCVTPVQTVV 15 0 Q13614;Q13614-2 Q13614 MTMR2 Myotubularin-related protein 2 1 AS(0.237)S(0.762)PAQCVT(0.002)PVQTVV 106.6 0.0009257 3615400.0 11862.0 13156.0 15918.0 10429.0 11277.0 12744.0 11678.0 12350.0 11838.0 10077.0 True False 11692.845704775611 13125.538090302238 14609.283485256923 11195.983450124128 10613.709031435033 12198.96882771497 12282.629699107154 12923.826085891604 10504.679780333588 11818.796023241528 0.9893432192062341 1.1105647364157074 1.236105899156558 0.9473032132974758 0.8980363998636829 1.0321667963239096 1.0392454252491965 1.0934976845760809 0.8888113272854744 1.0 13.528795455693649 -5.789554115896989 24.999995107861505 0.9900053552666038 1.1118608338234137 0.33625376112865735 0.08123045322959438 251.71680391038316 223829.01242701826 0.023721993557079338 0.03519395216792927 1.6234760422794585e-06 5.789554115896989 0.12185547855680989 ASS(ph)PCHSPR ddPTM_PC-9_AZD4547_30min_R2 2 ASSPCHSPR 9 0 A0A494BYR6;Q86Y91-6;Q86Y91 A0A494BYR6 KIF18B Kinesin-like protein KIF18B 1 AS(0.029)S(0.963)PCHS(0.008)PR;AS(0.039)S(0.961)PCHSPR 139.15 0.00084761 26896000.0 99857.0 65862.0 115944.0 184977.0 139735.0 138544.0 121107.0 123935.0 148113.0 206603.0 True False 131609.44884537047 87150.60349839258 114406.50680353631 142333.4105161614 120335.20725167287 129880.821778552 131885.2883846535 104783.6934929787 155941.9508013174 199369.8918550585 0.6601270012276993 0.43713021403327484 0.5738404416987376 0.7139162748788443 0.6035776321690354 0.6514565492816492 0.6615105578756789 0.5255743107347233 0.7821740251265566 1.0 17.605088029854592 -14.52287874527639 0.19129345654671093 2.688682819451275 0.5481565888027776 0.6691459231452956 0.08372028138455784 81.31619885312513 0.7944014764234579 52.12241611577986 0.22269815938136944 3.0000000000272664e-15 14.52287874527639 -2.140526230648497 ASS(ph)PCHSPR ddPTM_PC-9_Lapatinib_30min_R1 1 ASSPCHSPR 9 0 A0A494BYR6;Q86Y91-6;Q86Y91 A0A494BYR6 KIF18B Kinesin-like protein KIF18B 1 AS(0.024)S(0.966)PCHS(0.01)PR 139.15 0.00084761 10169000.0 29419.0 36749.0 56735.0 45986.0 51965.0 44255.0 43938.0 50883.0 71371.0 51134.0 True False 28999.47966521615 36663.90994835183 52070.4673034333 49367.963844798986 48908.52086712084 42362.3168134437 46212.89464971489 53247.20993752408 63332.44641005142 59972.44376822782 0.4835467398542042 0.6113459389789886 0.8682398787127493 0.8231774585606119 0.8155165571730725 0.7063630252780593 0.7705688103741662 0.8878612674732018 1.0560257750177535 1.0 15.872012140755201 -3.87467161981373 0.2312158957940538 0.9983042367221783 7.21812800338995e-25 0.6603883725192848 0.0946910814755636 13.250689133012706 0.43856244349114454 0.16857688038738342 4.04267294519982 0.00013345301201164085 3.87467161981373 -0.9983042367221783 ASS(ph)PEKAEEDR ddPTM_PC-9_AZD4547_30min_R2 3 ASSPEKAEEDR 11 1 Q8N3D4;H0YDZ9 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 AS(0.057)S(0.943)PEKAEEDR;AS(0.057)S(0.943)PEKAEEDR;AS(0.123)S(0.877)PEKAEEDR 145.0 0.00085811 31279300.0 58712.0 59006.0 46849.0 64748.0 56589.0 56557.0 54919.0 51726.0 53971.0 53010.0 True False 77381.19471453542 78078.53557477987 46227.751649407204 49821.34894662803 48732.59414724236 53020.48184930106 59806.684607799674 43732.9352452319 56823.796876019696 51154.13603498825 1.5127065123650698 1.526338662456853 0.90369528707881 0.973945663211893 0.9526618554149832 1.0364847490149431 1.1691466075566848 0.8549247164553728 1.110834847003447 1.0 15.642563272421901 -5.255397778159451 24.921171317316368 0.9997230243294323 1.519522664459522 0.8509788778562488 0.08692625231789892 153.74558347537666 634184.7089578047 0.021841668404347682 0.054712366443201106 5.553953276258935e-06 5.255397778159451 0.5197996401300898 ASS(ph)PEKAEEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSPEKAEEDR 11 1 Q8N3D4;H0YDZ9 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 AS(0.134)S(0.866)PEKAEEDR 179.59 0.009224 11643000.0 20731.0 21058.0 15873.0 20483.0 19475.0 17848.0 20040.0 17983.0 14615.0 13478.0 True False 24240.348844085987 23148.49907252629 16251.47251868773 19335.403916781976 15659.013552457262 16912.0194603917 18141.666122964292 17510.96530456348 14828.716726136441 15921.454708210704 1.5224958578430163 1.4539185958044774 1.0207278679319947 1.2144244524849037 0.9835165089771539 1.0622157189989783 1.139447773802266 1.0998345079318075 0.9313669509413146 1.0 13.958684537318058 -5.219476617860094 5.351780868083429 1.0658925246075213 1.498978486882757 0.8282966662624273 0.07860100282136702 0.07345366897869159 5.374466070060021 0.01976853403660412 0.05316863502398841 6.032861875985959e-06 5.219476617860094 0.43308596227523566 ASS(ph)PEKAEEDR ddPTM_PC-9_Lapatinib_30min_R1 3 ASSPEKAEEDR 11 1 Q8N3D4;H0YDZ9 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 AS(0.148)S(0.852)PEKAEEDR;AS(0.007)S(0.993)PEKAEEDR;AS(0.184)S(0.816)PEKAEEDR 201.38 0.00016587 37246000.0 116838.0 102781.0 73440.0 87567.0 80393.0 68689.0 67812.0 75697.0 79383.0 66573.0 True False 115171.8686945349 102543.01690934564 67402.04668659803 94006.96929494872 75664.44179871923 65751.33159187961 71322.97355333564 79214.15896548473 70442.05059995105 78080.05434705327 1.4750485211320998 1.3133061672006328 0.8632428249474159 1.2039818629877341 0.969062360822688 0.842101509043853 0.9134595787589557 1.0145248953515138 0.9021772741966531 1.0 16.252666436627976 -5.10611334963215 3.8101302366024647 0.9671547042697087 1.449085066932811 0.7606477416884925 0.09816599973620287 0.10698826961421987 2.7029811684885976 0.02614076560929916 0.08541223133032216 7.83225196525089e-06 5.10611334963215 0.4819303626631023 ASS(ph)PFR ddPTM_PC-9_AZD4547_30min_R2 2 ASSPFR 6 0 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 AS(0.006)S(0.994)PFR;AS(0.006)S(0.994)PFR 107.32 0.032037 260730000.0 137767.0 149963.0 194174.0 201931.0 168914.0 204462.0 170591.0 216454.0 172394.0 172418.0 True False 181574.04026838488 198435.60706370044 191599.12588896242 155378.92775285 145463.2067678752 191676.95881803829 185773.26852144374 183006.00791809533 181506.39489067357 166381.69829995467 1.091310174878978 1.1926528523946105 1.151563710712614 0.9338703074945853 0.8742740833528013 1.1520315081318682 1.1165486974807153 1.0999166962953473 1.0909036074595893 1.0 17.344137222675272 -5.646962891327679 23.742158178959247 1.0434785304945715 1.149946555087643 0.25245518780236165 0.08387905878122427 8.28659994475671 1683.9119823712947 0.025166482938975478 0.04358960474243269 2.2544318358252993e-06 5.646962891327679 0.10646802459307159 ASS(ph)PFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASSPFR 6 0 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 AS(0.096)S(0.904)PFR;AS(0.099)S(0.901)PFR 107.32 0.032037 354980000.0 153366.0 214089.0 203205.0 181753.0 213260.0 132809.0 171048.0 141174.0 146460.0 109151.0 True False 179327.83468342526 235342.34105509007 208050.17785925395 171569.96866117633 171473.2338997197 125844.26224311744 154845.09515972066 137468.3320862171 148601.70042490173 128939.21226115947 1.3907936270015853 1.8252193179094096 1.6135524190876818 1.330626778715466 1.329876543315697 0.9759968285538043 1.2009154736116288 1.0661483785691381 1.152494247629782 1.0 16.976331549088805 -6.1345997910526515 1.4736332401475825 1.0949903004660706 1.63665496562438 0.7452328816069693 0.13008088897945194 0.18919039354792647 0.8243451127809419 0.045232657429984 0.06983896708466061 7.33500153302361e-07 6.1345997910526515 0.5416646651583095 ASS(ph)PFR ddPTM_PC-9_Lapatinib_30min_R1 3 ASSPFR 6 0 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 AS(0.096)S(0.904)PFR;AS(0.115)S(0.885)PFR;AS(0.096)S(0.904)PFR 107.32 0.032037 305219000.0 130753.0 218713.0 215903.0 180446.0 230691.0 196904.0 224710.0 235122.0 227972.0 192326.0 True False 128888.43824283665 218206.58348618675 198152.28874968144 193716.60079020984 217122.20893595635 188482.87492564257 236344.38428552594 246046.62647506048 202295.39270841453 225569.2928417138 0.5713917733176567 0.967359434155368 0.8784541825412763 0.8587897685441804 0.9625521550414005 0.835587470932511 1.0477684320772032 1.0907806792998018 0.8968215050900966 1.0 17.783211158839144 -4.759505366331013 24.990485105587453 0.9465085680109947 0.5713912969988744 0.6747972658165746 0.0785619419382915 31.735312894302997 409960.9216323351 0.020610830056736196 0.13042097378023185 1.7397812004142493e-05 4.759505366331013 -0.37511727101212033 ASS(ph)PFRR ddPTM_PC-9_AZD4547_30min_R2 2 ASSPFRR 7 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 AS(0.002)S(0.998)PFRR;ASS(1)PFRR 80.219 0.037792 484440000.0 1080800.0 929550.0 1422450.0 2115040.0 1542390.0 1351220.0 1327200.0 1735530.0 1164120.0 1427930.0 True False 1424471.9179634496 1230008.8591590114 1403587.3835876824 1627450.2050422584 1328255.7720893645 1266727.9997951163 1445318.2288729188 1467343.7170118948 1225653.0066019164 1377938.6053280649 1.0337702365369943 0.8926441674563332 1.0186138759451557 1.1810759918833893 0.9639440878957943 0.9192920460295317 1.048898857528425 1.064883233068678 0.8894830305665964 1.0 20.39408017887441 ASS(ph)PFRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASSPFRR 7 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 AS(0.001)S(0.999)PFRR;ASS(1)PFRR 80.219 0.037792 448150000.0 380008.0 372501.0 434663.0 426467.0 508883.0 434087.0 452673.0 451587.0 412367.0 302435.0 True False 444335.84889988013 409480.4375066534 445027.01438860706 402573.4366146695 409171.0291971807 411322.7135535104 409792.536371287 439733.31974597723 418397.0872532819 357264.0714258577 1.2437182589520264 1.1461562196064041 1.245652865714941 1.1268231787427714 1.1452901702770164 1.1513128423798735 1.1470297999342216 1.2308355497125163 1.1711143681015543 1.0 18.446631309764925 -11.929780330292164 1.8483675878071344 1.0143731173355492e-05 1.1769677086136603 0.6128536174691117 0.042580548118528 602722.330820383 54359.30214881947 2515070.6463832567 0.010537662637028598 1.175491978070058e-12 11.929780330292164 1.176957564882487 ASS(ph)PFRR ddPTM_PC-9_Lapatinib_30min_R1 1 ASSPFRR 7 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 ASS(1)PFRR 101.72 0.016316999999999998 382080000.0 943420.0 781500.0 968710.0 902930.0 787530.0 874710.0 770370.0 698840.0 1061500.0 695250.0 True False 929966.6577979595 779690.4847652154 889066.4031287363 969334.4842861817 741209.0337435517 837300.6923486012 810255.9891506403 731310.6576408471 941942.6919094532 815423.0361376071 1.1404714075811597 0.9561791244681471 1.0903130813423592 1.188750429320225 0.9089871157606941 1.026829823590245 0.993663354163452 0.8968481698834843 1.1551583045423006 1.0 19.637189188746767 -6.269592370653343 24.882292261669672 0.9930900883517365 1.0838310253524484 0.2290945361539949 0.08622158617759608 928.8788640098276 2834861.415340941 0.02604923926413209 0.030074024196094864 5.375360917185189e-07 6.269592370653343 0.09074093700071184 ASS(ph)PGYIDSPTYSR ddPTM_PC-9_AZD4547_30min_R2 3 ASSPGYIDSPTYSR 14 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 AS(0.006)S(0.994)PGYIDSPTYSR;AS(0.408)S(0.592)PGYIDSPTYSR;AS(0.059)S(0.941)PGYIDSPTYSR 293.53 1.6902e-98 432987000.0 466220.0 500186.0 712383.0 875998.0 845687.0 769391.0 667353.0 923957.0 725064.0 794237.0 True False 614468.2620215763 661861.3428296584 702936.335957217 674050.1951341863 728277.9576702014 721280.8591423816 726746.1241659344 781180.67606965 763389.4027925065 766431.004376927 0.8017267810311387 0.8635628504717409 0.9171554020425775 0.8794662419511042 0.950219854769912 0.9410903982528076 0.9482211967099966 1.0192446177261758 0.9960314737177246 1.0 19.547796397927527 -1.9401170990491619 0.2305002149003801 1.0207836852579295 0.003175422701574357 0.8827768868540329 0.0220952847671612 13.334699600988317 0.20700074583828945 0.03339078197800923 4.925596279602153 0.011478440859651226 1.9401170990491619 -1.0176082625563552 ASS(ph)PGYIDSPTYSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ASSPGYIDSPTYSR 14 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 ASS(1)PGYIDSPTYSR;AS(0.003)S(0.997)PGYIDSPTYSR;AS(0.102)S(0.898)PGYIDSPTYSR;ASS(1)PGYIDSPTYSR;AS(0.005)S(0.995)PGYIDSPTYSR 276.32 1.1439999999999998e-69 401635000.0 143645.0 160510.0 201921.0 201618.0 212291.0 174600.0 190204.0 168439.0 160127.0 133010.0 True False 167961.26138192718 176444.37202636496 206735.5624296572 190321.9971143754 170694.10249369463 165443.66863426674 172186.5001622907 164017.65472587265 162468.55444447795 157123.6600934195 1.0689749798474915 1.1229650068071106 1.3157506788394597 1.2112879562582586 1.086367911695837 1.0529519776709664 1.0958661481021728 1.043876234988125 1.0340171196870072 1.0 17.26154091623568 -6.404322558742964 4.123535174001996 1.0527050988760105 1.18482050942948 0.4974873002649838 0.06349954086861238 0.22127823798940194 6.366993710535217 0.021992002234678842 0.02492448785644778 3.94164439931408e-07 6.404322558742964 0.13211541055346943 ASS(ph)PGYIDSPTYSR ddPTM_PC-9_Lapatinib_30min_R1 5 ASSPGYIDSPTYSR 14 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 AS(0.039)S(0.961)PGYIDSPTYSR;AS(0.466)S(0.534)PGYIDSPTYSR;AS(0.006)S(0.994)PGYIDSPTYSR;AS(0.002)S(0.981)PGY(0.014)IDS(0.002)PT(0.001)YSR;AS(0.092)S(0.908)PGYIDSPTYSR 258.6 5.5233e-45 418305000.0 439884.8 551583.0 596463.6 522564.2 535559.7 573677.8 469809.5 503001.7 535670.0 395030.4 True False 433611.9620870072 550305.8434526587 547424.6652240792 560995.3144910702 504059.13139688206 549142.9378022689 494133.9371144619 526372.9952799864 475337.20374483 463310.8782950795 0.9358985130732085 1.1877680176163978 1.1815493459564923 1.210839936578774 1.0879501324289007 1.1852580276617712 1.06652781159123 1.1361118849981828 1.0259573560931823 1.0 18.821621030924376 -8.338623774467539 3.205896272586847 0.9995732236826055 1.130521633813686 0.24781308728215867 0.07701651448420432 0.32753569193648313 6.175602975787762 0.0709650724473094 0.01936425292149677 4.5853894300474725e-09 8.338623774467539 0.1309484101310806 ASS(ph)PIKQSHEPVPDTSVEK ddPTM_PC-9_AZD4547_30min_R2 2 ASSPIKQSHEPVPDTSVEK 19 1 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 AS(0.154)S(0.846)PIKQSHEPVPDTSVEK;AS(0.122)S(0.439)PIKQS(0.439)HEPVPDTSVEK 109.85 7.3998e-05 55813000.0 102296.0 78070.0 106485.0 159358.0 145062.0 109961.0 92768.0 105829.0 91006.0 116943.0 True False 134824.00011101857 103304.60075794092 105072.93932393704 122620.47515655693 124922.64525238621 103085.12128703782 101024.17228457106 89475.55975849001 95816.39136756868 112848.86116467886 1.1947307107891119 0.9154243976568791 0.9310943702888191 1.0865902756219974 1.106990748183876 0.9134795001307727 0.8952165865205127 0.7928795987397649 0.8490683058621662 1.0 16.784032333814054 -6.9197779124336725 5.4796604543087355 0.8717759842901258 1.034971173526557 0.42423773415901134 0.09074377591160668 0.2080071475849384 10.59714493903219 0.03314549029567524 0.029095191031212834 1.202879400443153e-07 6.9197779124336725 0.16319518923643117 ASS(ph)PIKQSHEPVPDTSVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASSPIKQSHEPVPDTSVEK 19 1 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 AS(0.202)S(0.761)PIKQS(0.037)HEPVPDTSVEK;AS(0.185)S(0.787)PIKQS(0.028)HEPVPDTSVEK 81.854 0.0009595000000000001 77987000.0 127502.0 70550.0 95587.0 154097.0 151717.0 150701.0 140602.0 161483.0 156726.0 119510.0 True False 149085.57032071037 77553.73775129326 97866.15659571633 145463.44467921485 121989.1429595973 142797.97426605172 127283.16068967158 157244.24235538184 159017.82125353778 141176.2169593602 1.0560246869600352 0.549339962648371 0.693219854615375 1.030367917572751 0.8640913150032473 1.0114874682267365 0.9015906746269596 1.1138153843621343 1.126378257460416 1.0 17.10713754204903 -6.46678309519328 0.8103689242796782 1.0614546344476457 0.7606817142736113 0.32446648852723337 0.14604832165591214 0.7181070028522735 1.0424889522945073 0.08671342336367067 0.11508154460825859 3.413633601761945e-07 6.46678309519328 -0.30077292017403434 ASS(ph)PPDR ddPTM_PC-9_AZD4547_30min_R2 1 ASSPPDR 7 0 Q9NWB6-2;Q9NWB6 Q9NWB6-2 ARGLU1 Arginine and glutamate-rich protein 1 1 AS(0.01)S(0.99)PPDR 69.812 0.045593 21642000.0 265800.0 262940.0 221520.0 229480.0 184360.0 201900.0 160370.0 199460.0 304690.0 385470.0 True False 350318.87101654714 347930.21292805206 218582.50006140312 176576.93143065725 158764.79628524295 189275.16108304684 174642.6193221443 168638.04013482484 320795.29136303667 371974.8126279363 0.9417811613146767 0.9353596026300453 0.5876271528095045 0.47470131158390116 0.4268159856405269 0.5088386489016589 0.4695011957619525 0.45335876088874644 0.862411325908533 1.0 18.50484541048248 -5.272855063308718 5.0998810107767145 0.5585371204754523 0.9435217452570612 0.34303512863868324 0.1825442610027605 0.15544914745799968 13.01216149152997 0.04559973516071976 0.10880729795995037 5.33512914546918e-06 5.272855063308718 0.3849846247816089 ASS(ph)PPDRIDIFGR ddPTM_PC-9_AZD4547_30min_R2 3 ASSPPDRIDIFGR 13 1 Q9NWB6-2;Q9NWB6 Q9NWB6-2 ARGLU1 Arginine and glutamate-rich protein 1 1 AS(0.201)S(0.799)PPDRIDIFGR;AS(0.032)S(0.968)PPDRIDIFGR;AS(0.427)S(0.573)PPDRIDIFGR 78.508 0.0070395 397950000.0 67985.0 48710.2 80571.0 154072.0 108523.0 92753.0 61124.0 76958.0 64732.0 76001.0 True False 89602.81582415359 64454.81957012241 79502.57589584378 118553.08078867098 93456.45469333565 86953.14024732963 66563.91758712193 65065.90941891031 68153.60136700276 73340.22812290398 1.2217417114383209 0.8788467287299495 1.0840241151501862 1.6164809385375656 1.274286392138306 1.1856131685548217 0.9076044524373954 0.8871789887246121 0.9292799206022452 1.0 16.162317133072037 -7.236143707174235 5.700484050949734 0.9208447807661662 1.212114365137046 0.3814602932474396 0.17407096822565926 0.21611650930474297 23.446110627472702 0.07676888207550758 0.05716785450476354 5.805722755301917e-08 7.236143707174235 0.2912695843708799 ASS(ph)PPDRIDIFGR ddPTM_PC-9_Lapatinib_30min_R1 4 ASSPPDRIDIFGR 13 1 Q9NWB6-2;Q9NWB6 Q9NWB6-2 ARGLU1 Arginine and glutamate-rich protein 1 1 AS(0.21)S(0.79)PPDRIDIFGR;AS(0.184)S(0.816)PPDRIDIFGR;AS(0.209)S(0.791)PPDRIDIFGR;AS(0.201)S(0.799)PPDRIDIFGR 77.74 0.0074453 327741500.0 221999.0 129058.0 169094.0 139576.0 126109.0 138163.0 107004.0 90979.0 162955.0 99239.0 True False 218833.25355036967 128759.17413030006 155191.74404171575 149840.88465188703 118691.51655983343 132254.09056368357 112544.14354540683 95206.21647516843 144601.29190777664 116392.3289223443 1.8801346753390669 1.1062513768944926 1.3333502772786512 1.2873776651712094 1.0197537729399944 1.1362784110276036 0.9669378092820452 0.8179767288503093 1.2423610150824722 1.0 16.828636452009626 -1.5228787452803376 0.6751778913165434 1.0403910987804181 78.797243213277 0.675787415089451 0.15810375237579977 151.9223502219976 0.8899931977356187 0.06408496274758299 17751.433213982116 0.029999999999999995 1.5228787452803376 77.75685211449658 ASS(ph)PSEHGPR ddPTM_PC-9_AZD4547_30min_R2 3 ASSPSEHGPR 10 0 C9J052;Q9NSU2-2;Q9NSU2;Q9NSU2-1 C9J052 TREX1 Three-prime repair exonuclease 1 1 AS(0.21)S(0.723)PS(0.067)EHGPR;AS(0.313)S(0.663)PS(0.024)EHGPR;AS(0.037)S(0.957)PS(0.005)EHGPR 132.03 9.0752e-05 17533300.0 19048.64 16002.180000000002 69778.8 132232.6 97822.5 87160.6 42810.8 111521.0 62803.1 87648.9 True False 25105.711283674387 21174.57174531457 68853.48751934209 101748.41704330455 84241.53441426082 81710.43390339272 46620.87826449119 94287.99194763762 66122.74365093031 84580.33868924867 0.29682680009019247 0.25034862798446267 0.8140602010629489 1.20297954134627 0.9959942903961093 0.9660688898823154 0.5512023123456391 1.1147743483749246 0.7817744014228619 1.0 16.368034716983097 -5.31991003286224 4.243722370525783 0.9397954740652056 0.26715498008821453 0.7069845844702232 0.16989951872765005 0.10827574132277971 3.998994757858127 0.04561350576372156 0.105617146229718 4.787292541626937e-06 5.31991003286224 -0.672640493976991 down ASS(ph)PSEHGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASSPSEHGPR 10 0 C9J052;Q9NSU2-2;Q9NSU2;Q9NSU2-1 C9J052 TREX1 Three-prime repair exonuclease 1 1 AS(0.039)S(0.827)PS(0.134)EHGPR;AS(0.203)S(0.785)PS(0.013)EHGPR 144.7 7.6228e-05 8923900.0 13940.2 22927.0 62355.0 49025.0 81106.0 72441.0 52141.0 41082.0 57577.0 43328.0 True False 16300.000528499722 25203.04104073561 63841.77968265439 46278.28819119448 65213.8615242926 68642.06643490774 47201.82701185032 40003.64102997703 58418.954700017675 51183.02341574071 0.31846498000129586 0.4924101656914766 1.2473233393051306 0.9041726162851521 1.2741307013965275 1.3411100371573148 0.922216466746159 0.7815802654923741 1.1413736587130108 1.0 15.643377750413794 -5.154382590116859 4.730489427333017 1.072660412565183 0.3620900204650019 0.711275361719057 0.1719810865136307 0.12057413678845806 4.209721197737686 0.04679051435496115 0.13478806840468752 7.008376260783761e-06 5.154382590116859 -0.7105703921001811 down ASS(ph)PSEHGPR ddPTM_PC-9_Lapatinib_30min_R1 2 ASSPSEHGPR 10 0 C9J052;Q9NSU2-2;Q9NSU2;Q9NSU2-1 C9J052 TREX1 Three-prime repair exonuclease 1 1 AS(0.139)S(0.723)PS(0.139)EHGPR;AS(0.157)S(0.589)PS(0.254)EHGPR 128.85 0.00015075 3941700.0 7401.5 6339.9 15630.2 7479.9 11223.7 13110.0 8636.5 10643.5 20718.9 6138.799999999999 True False 7295.953252731135 6325.220351072296 14345.145290316796 8029.996798214935 10563.544032643204 12549.31586090265 9083.65571128095 11138.035866007061 18385.31930231066 7199.883400563166 1.013343251108824 0.8785170535647209 1.9924135561965817 1.1152953945874788 1.46718265351588 1.742988762834834 1.2616392802375713 1.5469744781055563 2.5535579230175567 1.0 12.81375782749601 -4.371077397475775 0.7109989051065791 1.6126939404199385 2.940061954145056e-11 0.1796417882291944 0.450538567142122 8.274088451103637 2.107396498310757 0.1807035220927116 12.235060878308426 4.255225721797215e-05 4.371077397475775 -1.6126939403905378 ASS(ph)PSGK ddPTM_PC-9_Lapatinib_30min_R1 1 ASSPSGK 7 0 P26639;P26639-2;D6RCA5;D6R9F8;D6RDJ6;D6RJ97;D6RHV7;D6RCS6 P26639 TARS Threonine--tRNA ligase, cytoplasmic 1 AS(0.002)S(0.963)PS(0.035)GK 73.248 0.036765 1302900.0 57632.0 18958.0 16503.0 19729.0 35878.0 20951.0 34765.0 39137.0 32635.0 18894.0 True False 56810.15711158562 18914.103915776046 15146.187043422231 21179.93647401469 33767.72657886198 20054.974569166392 36564.96159354856 40955.44789664289 28959.30263821478 22159.802725327503 2.563658071136823 0.8535321433235599 0.683498279797903 0.9557818152328189 1.5238279418556024 0.9050159343812478 1.6500580825007396 1.848186484522849 1.3068393702402323 1.0 14.435657417594559 -7.2828863527842165 24.128235914757834 1.5219531921939407 1.203299166765486 0.022581578158482163 0.5419991678028998 1578.1661852529837 1775455.8773666068 0.22614451118042836 0.15265190999544231 5.213311164267485e-08 7.2828863527842165 -0.31865402542845467 ASS(ph)PSLIER ddPTM_PC-9_AZD4547_30min_R2 1 ASSPSLIER 9 0 A1L170;A1L170-2 A1L170 C1orf226 Uncharacterized protein C1orf226 1 AS(0.391)S(0.608)PS(0.001)LIER 87.29799999999999 0.010998 7171300.0 33266.0 33446.0 49472.0 53375.0 51499.0 48209.0 48003.0 47621.0 47801.0 48458.0 True False 43843.89602421547 44256.7654278224 48815.968955569464 41070.218385529595 44349.25278744692 45194.48360897774 52275.17400586702 40262.26867171613 50327.663272324375 46761.50016946729 0.9376067034915861 0.9464359626494544 1.0439350486758685 0.8782912916969718 0.948413815354978 0.9664891726139974 1.117910542142954 0.8610131951670189 1.0762628035869901 1.0 15.513033593686213 -7.0188233551382035 24.857605523533365 1.0079266057836958 0.9523806749700436 0.14302136715734326 0.07249377170287519 1563.7570587204432 2065050.2391983736 0.026283753603144628 0.02071398889130975 9.575834794329285e-08 7.0188233551382035 -0.05554593081365211 ASS(ph)PSLIER ddPTM_PC-9_Lapatinib_30min_R1 4 ASSPSLIER 9 0 A1L170;A1L170-2 A1L170 C1orf226 Uncharacterized protein C1orf226 1 AS(0.275)S(0.681)PS(0.044)LIER;AS(0.03)S(0.966)PS(0.004)LIER;AS(0.025)S(0.964)PS(0.011)LIER;AS(0.255)S(0.577)PS(0.168)LIER 110.53 0.0022954 31520900.0 155884.0 161399.0 218855.0 154982.0 167964.0 171174.0 126252.0 131898.0 210350.0 134353.0 True False 153661.0655743753 161025.29053182536 200861.58670473113 166379.89328479613 158084.68774992964 163853.2870460833 132788.71080421968 138026.46259732233 186658.16791630085 157575.73703588088 0.9751568894098577 1.0218914000393284 1.2746986971667713 1.0558725373241344 1.0032298799524755 1.0398383033345608 0.8426976976409949 0.8759372806607462 1.1845616046447414 1.0 17.26568588516527 -6.4071727684155295 2.2493736011977403 0.9724901640349453 1.0917303994897412 0.12897713154975976 0.11352854255111856 0.5780259753077202 5.754206700499414 0.04104430907462343 0.04763982257166563 3.91586067706881e-07 6.4071727684155295 0.1192402354547959 ASS(ph)PSPLTIGTPESQR ddPTM_PC-9_AZD4547_30min_R2 2 ASSPSPLTIGTPESQR 16 0 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 AS(0.023)S(0.875)PS(0.098)PLT(0.004)IGTPESQR;AS(0.048)S(0.817)PS(0.132)PLT(0.002)IGTPESQR 90.853 0.0034106 8133400.0 14370.6 18146.6 27122.0 29153.0 29152.0 24746.0 26542.0 32544.0 25583.0 26898.0 True False 18940.15187295109 24012.133573895884 26762.344558800018 22432.22625936009 25104.748000148604 23198.62870807865 28904.18658133288 27515.07258672285 26935.265151270374 25956.309207114024 0.7296935678266628 0.9250981479028888 1.031053542522335 0.864230198537315 0.967192515693563 0.8937568327981099 1.1135707450044905 1.0600533522378293 1.037715529443918 1.0 14.66379763703361 -7.251856814351571 24.798306366224484 1.0578393534531976 0.9100294858503039 0.4751609406427899 0.07738615567168002 556.162846468846 1439271.6848020896 0.0299790717902088 0.022914259609411895 5.5994218240142054e-08 7.251856814351571 -0.14780986760289372 ASS(ph)RSPVFTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSRSPVFTPR 11 1 P52735-3 P52735-3 VAV2 Guanine nucleotide exchange factor VAV2 1 AS(0.34)S(0.625)RS(0.022)PVFT(0.012)PR 55.721000000000004 0.039458 11656000.0 17066.0 10759.0 15502.0 15560.0 20650.0 14524.0 19493.0 12429.0 10592.0 11272.0 True False 19954.936731135575 11827.082416246103 15871.626471662381 14688.22364620064 16603.78073726533 13762.335871959267 17646.481922901337 12102.751919614062 10746.887961904698 13315.52437089709 1.4986219224493955 0.8882175486904458 1.1919640586105646 1.1030901402804514 1.2469490704816084 1.0335556819706435 1.3252562521285418 0.908920413683917 0.8070946109635382 1.0 13.700821623148434 -7.84286916928475 8.688922112049845 0.890475055168033 1.1661986422971116 0.38048793015563387 0.16154953095554034 0.28826765234570917 27.594543449383302 0.08194835702879977 0.03928627593358648 1.4359219380438022e-08 7.84286916928475 0.2757235871290785 ASS(ph)SDMGSTAK ddPTM_PC-9_AZD4547_30min_R2 2 ASSSDMGSTAK 11 0 K7EJ41;Q13472-3;Q13472-2;Q13472 K7EJ41 TOP3A DNA topoisomerase 3-alpha 1 AS(0.054)S(0.941)S(0.005)DMGSTAK;AS(0.009)S(0.986)S(0.005)DMGSTAK 94.538 0.005804600000000001 15743400.0 143108.0 120678.0 126326.0 182489.0 171156.0 170104.0 122123.0 133666.0 161484.0 168345.0 True False 188613.36716868335 159684.8035130882 124650.83470005798 140418.9804769444 147393.9437676123 159467.36998945285 132991.71041640118 113010.99103911319 170019.71456387994 162451.29279023022 1.1610456520788397 0.982970346190385 0.7673120512559839 0.8643758880901263 0.9073116085197233 0.9816318925536011 0.8186559068392916 0.6956607675941477 1.0465888676147543 1.0 17.309647699142268 -4.888461669855367 3.418072200803352 0.8751212330621666 1.168317187597758 0.39859029472214214 0.10270510957116769 0.24788005400169014 4.9778278802905085 0.025637629622404456 0.16162165883393245 1.292820798092189e-05 4.888461669855367 0.29319595453559144 ASS(ph)SDMGSTAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSSDMGSTAK 11 0 K7EJ41;Q13472-3;Q13472-2;Q13472 K7EJ41 TOP3A DNA topoisomerase 3-alpha 1 AS(0.171)S(0.824)S(0.004)DMGSTAK 92.792 0.006563899999999999 6812800.0 28345.0 37503.0 35369.0 35412.0 72403.0 82370.0 72780.0 71288.0 89287.0 71704.0 True False 33143.248660731166 41226.04999130755 36212.33109767945 33427.98044725301 58216.15189928432 78050.37219590237 65885.7515184301 69416.76553587957 90592.65346059136 84703.3675914484 0.39128607991823555 0.48671087305706723 0.4275193788320575 0.3946475966396863 0.6872944199819723 0.9214553614015021 0.7778409925354831 0.8195278122907577 1.0695283556794208 1.0 16.37013170814945 -6.493885504144668 2.7245057780578894 0.8987007056287104 0.42879366640733535 0.8848347954897444 0.08342494610168666 0.09233137015018496 1.3727768957412634 0.02924367299784844 0.03181824287573846 3.2071147254013005e-07 6.493885504144668 -0.46990703922137506 ASS(ph)TPSSETQEEFVDDFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSTPSSETQEEFVDDFR 18 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0;F5H367;F5H270 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 AS(0.009)S(0.906)T(0.03)PS(0.046)S(0.002)ET(0.006)QEEFVDDFR 149.24 9.6064e-05 1711800.0 9203.5 13162.0 11838.0 15486.0 15532.0 14250.0 13652.0 15095.0 11922.0 10868.0 True False 10761.470772589142 14468.636375372364 12120.262815865004 14618.369626289397 12488.616097394919 13502.704914308695 12358.783728079254 14698.772244474543 12096.3366957919 12838.282368959332 0.8382329086800935 1.1269915989973032 0.9440719924629193 1.1386546273225768 0.9727637808925403 1.0517532272818535 0.9626508728270832 1.1449173512504713 0.9422083381682489 1.0 13.648164577060772 -4.743261679681361 24.99064919538249 1.0333389693654031 0.8382322899385024 0.3640782544659765 0.07661727579596517 1191.6806549113583 1638233.1481362684 0.017032427211200234 0.5495998910081593 1.8060855597798943e-05 4.743261679681361 -0.19510667942690074 ASS(ph)VGVLSPQKK ddPTM_PC-9_Lapatinib_30min_R1 1 ASSVGVLSPQKK 12 1 Q9UGU5 Q9UGU5 HMGXB4 HMG domain-containing protein 4 1 AS(0.005)S(0.969)VGVLS(0.027)PQKK 137.95 9.980299999999999e-05 12860000.0 26762.0 20824.0 24657.0 23830.0 21809.0 24398.0 24561.0 20713.0 24874.0 20325.0 True False 26380.368972450262 20775.78330742275 22629.796638772466 25582.537694549646 20526.237498143713 23354.55441451586 25832.648402104034 21675.401596524098 22072.428185167904 23838.14916863986 1.1066450161808201 0.8715350827133095 0.9493101363986332 1.0731763407288604 0.8610667444411703 0.9797134101853767 1.0836683762382033 0.9092736790589031 0.9259287719453136 1.0 14.540984606587745 -4.7349491446486764 24.70381302945547 0.9630383305336546 1.1066458503058882 0.2686210797904123 0.07180075841222056 3427.668571472459 3196322.207418158 0.017778613726438925 1.4549017571873848 1.840987566234216e-05 4.7349491446486764 0.14360751977223363 ASS(ph)VTTFTGEPNTCPR ddPTM_PC-9_AZD4547_30min_R2 1 ASSVTTFTGEPNTCPR 16 0 H0YFA4;P52943;P52943-2 H0YFA4 CRIP2 Cysteine-rich protein 2 1 AS(0.005)S(0.916)VT(0.062)T(0.016)FTGEPNTCPR 104.94 0.0011872999999999999 12554000.0 25747.0 28556.0 35521.0 49663.0 60966.0 40319.0 41656.0 60515.0 50155.0 47326.0 True False 33934.0104291311 37786.16855698427 35049.96833099092 38213.96263570128 52501.92324976191 37797.84655625243 45363.303301635206 51163.79724635982 52806.09090653812 45669.13114491327 0.7430404209235925 0.827389696490711 0.7674761365565166 0.8367569445200106 1.1496151105473722 0.8276454053026677 0.993303401321395 1.1203146625236062 1.1562753567388544 1.0 15.478931722257864 -6.176775650827353 0.6106116642352201 1.0844376073721107 0.7243916008861163 0.5820099781073751 0.09892874662413109 0.7589416560069875 0.5738668633586894 0.07026668174377612 0.15383907839717206 6.656169138269207e-07 6.176775650827353 -0.3600460064859944 ASS(ph)VTTFTGEPNTCPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ASSVTTFTGEPNTCPR 16 0 H0YFA4;P52943;P52943-2 H0YFA4 CRIP2 Cysteine-rich protein 2 1 AS(0.149)S(0.823)VT(0.027)TFTGEPNTCPR;AS(0.001)S(0.823)VT(0.169)T(0.007)FTGEPNTCPR;AS(0.019)S(0.98)VT(0.001)TFTGEPNTCPR;AS(0.016)S(0.678)VT(0.211)T(0.066)FT(0.03)GEPNTCPR 182.7 7.5361e-07 57386000.0 106590.0 95263.0 101418.0 108635.0 184919.0 180436.0 131892.0 185295.0 143651.0 130594.0 True False 124633.58175153771 104720.08106876575 103836.18974990692 102548.53314942213 148685.44940214872 170973.61852057578 119398.23494461113 180431.20258628106 145751.62411400813 154269.65841846506 0.8078943262677238 0.6788119072948661 0.6730823858327699 0.6647355948066827 0.9638022857277038 1.108277676072895 0.7739579912774343 1.1695832118643275 0.9447847723798591 1.0 17.235094816620204 -6.306209016500453 5.751635227739905 0.9985827605903482 0.7016752035780123 0.6444704023163146 0.1045826926762603 0.12311321359432933 10.458628404028964 0.0312813527625664 0.03606451508821371 4.940728432296472e-07 6.306209016500453 -0.29690755701233595 ASS(ph)VTTFTGEPNTCPR ddPTM_PC-9_Lapatinib_30min_R1 4 ASSVTTFTGEPNTCPR 16 0 H0YFA4;P52943;P52943-2 H0YFA4 CRIP2 Cysteine-rich protein 2 1 AS(0.223)S(0.766)VT(0.007)T(0.004)FTGEPNTCPR;AS(0.009)S(0.93)VT(0.041)T(0.013)FT(0.008)GEPNTCPR;AS(0.147)S(0.852)VT(0.001)TFTGEPNTCPR;AS(0.005)S(0.992)VT(0.003)TFTGEPNTCPR 212.43 3.9919e-18 52444700.0 134952.0 109100.0 151416.0 137031.0 168619.0 183208.0 182524.0 179354.0 233731.0 196031.0 True False 133027.5597328345 108847.38565308401 138967.1609626627 147108.71686201548 158701.1619377092 175372.6209187074 191974.19962320896 187687.4416039678 207405.75348345598 229914.69715511124 0.5785952850290725 0.4734250876517497 0.6044292195418414 0.6398404220447423 0.690261057259171 0.762772554728821 0.8349801121834945 0.8163351187477373 0.9020987176975916 1.0 17.810739166830743 -6.730936120258934 0.35627935679942924 1.0022249355541424 0.4356748952910141 0.9492362942428973 0.03463416462767927 0.3532998072741974 0.0914180029345205 0.03872272483076317 0.07559979098767884 1.858077736933537e-07 6.730936120258934 -0.5665500402631283 ASSAS(ph)VPAVGASAEGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSASVPAVGASAEGTR 17 0 V9GYZ0;Q9BZ23-3;Q9BZ23-4;Q9BZ23;A0A2R8YFI4 V9GYZ0 PANK2 Pantothenate kinase 2, mitochondrial 1 ASS(0.001)AS(0.694)VPAVGAS(0.304)AEGT(0.001)R 87.99 0.017308 0.0 7110.2 6012.8 7237.4 7782.2 11994.0 13568.0 9901.7 12234.0 14593.0 5147.6 True False 8313.816427148728 6609.71104678916 7409.967063992347 7346.188564232815 9643.861799649412 12856.47019490108 8963.739293899975 11912.870462994473 14806.395017756346 6080.819131620818 1.3672198181189306 1.0869770837974864 1.2185804089221859 1.20809193715892 1.585947812441986 2.1142661731289216 1.4741006268855634 1.9590897550375168 2.4349342904744087 1.0 12.570049963187506 -6.420471797903432 3.4969503117368097 1.8385268248528985 1.21090686410212 0.35229125149936413 0.3646295941327452 0.2534824575948975 5.752172389364927 0.11476576658974641 0.12952937321049227 3.7977659999983655e-07 6.420471797903432 -0.6276199607507786 ASSCET(ph)YEYPQR ddPTM_PC-9_Lapatinib_30min_R1 1 ASSCETYEYPQR 12 0 Q9UQC2-2;Q9UQC2 Q9UQC2-2 GAB2 GRB2-associated-binding protein 2 1 AS(0.096)S(0.235)CET(0.668)YEYPQR 140.91 0.00018786 8679300.0 11555.0 13232.0 14980.0 13217.0 15125.0 13958.0 11205.0 12748.0 13010.0 13371.0 True False 11390.223581072521 13201.362116971664 13748.402224472216 14189.022270619493 14235.377236894117 13361.048877687195 11785.140073513929 13340.318618862028 11544.676798626459 15682.159534262413 0.7263172878829053 0.8418076661016809 0.8766906237903447 0.904787522382953 0.9077434269044794 0.8519903683224207 0.7514998204020136 0.850668467548495 0.7361662641808755 1.0 13.936836621071803 -11.936183603871818 2.42852645292584 2.6826358815589257 0.833182419058194 0.39352924789176835 0.06388883606305083 5553925.599715936 1049580.4260769025 51759211.601941824 0.016995700109256315 1.1582875708789504e-12 11.936183603871818 -1.8494534625007317 ASSDGEGTMSRPAS(ph)VDGSPVSPSTNR ddPTM_PC-9_AZD4547_30min_R2 1 ASSDGEGTMSRPASVDGSPVSPSTNR 26 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 AS(0.001)S(0.004)DGEGT(0.025)MS(0.009)RPAS(0.897)VDGS(0.032)PVS(0.019)PS(0.007)T(0.007)NR 50.431999999999995 0.031777 4691500.0 10771.0 8125.1 11954.0 18864.0 19736.0 12963.0 13669.0 18766.0 12639.0 15569.0 True False 14195.953949282286 10751.379680009557 11795.482149395148 14515.19624589471 16995.997068157674 12152.421560770357 14885.51451963827 15866.14589978002 13307.071736970109 15023.934048834777 0.9448892615701606 0.7156168048303839 0.7851127481693105 0.9661381765064707 1.1312614267949244 0.8088708005020078 0.9907867321071445 1.056058010385806 0.8857248503431879 1.0 13.874975014611453 -5.783328379882113 8.313008735789264 0.9795828956087277 0.8051585639329063 0.3639575887784888 0.09770234007581294 0.18841976925640055 59.00982312182362 0.0268889748366823 0.0410391461081945 1.646916649683691e-06 5.783328379882113 -0.1744243316758214 ASSDGEGTMSRPAS(ph)VDGSPVSPSTNR ddPTM_PC-9_Lapatinib_30min_R1 1 ASSDGEGTMSRPASVDGSPVSPSTNR 26 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 ASSDGEGTMS(0.003)RPAS(0.487)VDGS(0.093)PVS(0.334)PS(0.067)T(0.016)NR 64.34899999999999 0.00081722 8440300.0 62555.0 59376.0 70485.0 63440.0 38904.0 31103.0 18617.0 23850.0 29244.0 17997.0 True False 61662.95422881797 59238.51852005059 64689.995379968146 68105.58922963621 36615.74320820688 29772.797194634273 19580.897166319388 24958.158068705634 25950.232767027846 21107.757470504876 2.9213408537114036 2.8064809159773647 3.064749794968192 3.2265667882911866 1.7347055109654463 1.4105144630469424 0.9276635470954666 1.182416374812964 1.2294168531777783 1.0 14.365485691629253 -6.452312330122302 2.666914596540771 1.1466904172799655 2.999699311955732 0.9622038463192686 0.1732653882571071 0.05186592521494462 0.7264884517638244 0.06291079882749956 0.070267212380334 3.52929263534401e-07 6.452312330122302 1.8530088946757666 up ASSDGEGTMSRPASVDGSPVS(ph)PSTNR ddPTM_PC-9_AZD4547_30min_R2 1 ASSDGEGTMSRPASVDGSPVSPSTNR 26 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 AS(0.004)S(0.011)DGEGT(0.061)MS(0.197)RPAS(0.197)VDGS(0.107)PVS(0.358)PS(0.049)T(0.015)NR 49.515 0.037538999999999996 6907800.0 11471.0 12322.0 18090.0 27213.0 28346.0 20558.0 16248.0 23282.0 15972.0 23785.0 True False 15118.539388377787 16304.845530156887 17850.11478020398 20939.463286658858 24410.64718757588 19272.505010130153 17694.040523453255 19684.301867136222 16816.24731251573 22952.294389590556 0.6586940343199165 0.7103797665453239 0.7777050292758295 0.9123037083454033 1.0635384320726875 0.8396766215612292 0.7709050878799267 0.8576180460661723 0.732660841094053 1.0 14.486350757111582 -5.4503875660189065 2.6931933236324785 0.8767793105995302 0.6810976098794701 0.4214213804006649 0.09327486730613968 0.2958348881533109 4.1557423313320445 0.027707161615147805 0.06719238957282261 3.5449689368075416e-06 5.4503875660189065 -0.19568170072006008 ASSDGEGTMSRPASVDGSPVS(ph)PSTNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSDGEGTMSRPASVDGSPVSPSTNR 26 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 ASSDGEGT(0.051)MS(0.19)RPAS(0.19)VDGS(0.035)PVS(0.296)PS(0.177)T(0.062)NR 65.33 0.00074821 9928300.0 22009.0 22058.0 34055.0 37921.0 29630.0 20966.0 20383.0 18160.0 19514.0 15899.0 True False 25734.68900243543 24247.772463756522 34867.0003543067 35796.409311540774 23824.214200734725 19866.506051466404 18452.174679859323 17683.31924211049 19799.355333139014 18781.362843585237 1.3702247923518018 1.291055003073876 1.8564680659590953 1.9059537696843452 1.2685029515241952 1.057777660594625 0.9824726157272262 0.9415354673343217 1.0542022694535969 1.0 14.197014133507276 -6.5448103873281775 3.686663449630658 1.0055088635095992 1.6028803891178016 0.7093198950506177 0.17993810931692042 0.13972251117430437 4.115168150518767 0.06781674469459063 0.07077596142809363 2.852263291885424e-07 6.5448103873281775 0.5973715256082024 ASSDGEGTMSRPASVDGSPVS(ph)PSTNR ddPTM_PC-9_Lapatinib_30min_R1 2 ASSDGEGTMSRPASVDGSPVSPSTNR 26 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 ASSDGEGTMSRPAS(0.003)VDGS(0.029)PVS(0.617)PS(0.176)T(0.176)NR;ASSDGEGT(0.004)MS(0.004)RPAS(0.001)VDGS(0.022)PVS(0.639)PS(0.073)T(0.256)NR 63.522 0.00039113 10407400.0 55028.0 49808.0 61855.0 43944.0 32718.0 27040.0 16799.1 15873.5 27812.0 13885.6 True False 54243.29062910074 49692.67263619437 56769.52066720483 47175.78835288665 30793.591566062907 25883.562233318666 17668.875199372414 16611.040759060746 24679.51968665635 16285.707458601024 3.3307297682332524 3.0513057392511382 3.4858492215653154 2.8967601482962624 1.8908353625006193 1.589342206908469 1.084931388107484 1.0199766145429503 1.5154097388395782 1.0 13.991318771978772 -6.399835611824958 1.530006064591904 1.179967747784506 3.2994980566312777 0.9588444518733381 0.1927392610733225 0.07027879157273464 0.3309884692952732 0.07448575408778711 0.09078640001478638 3.9825788971159856e-07 6.399835611824958 2.1195303088467714 ASSDLSIAS(ph)SEEDKLSQNACILESVSEK ddPTM_PC-9_AZD4547_30min_R2 1 ASSDLSIASSEEDKLSQNACILESVSEK 28 1 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 AS(0.007)S(0.011)DLS(0.083)IAS(0.703)S(0.193)EEDKLS(0.003)QNACILESVSEK 62.068999999999996 0.00047489 2109300.0 11720.0 10723.0 6577.5 11476.0 9059.3 10353.0 6163.3 7554.8 6907.6 5794.4 True False 15446.716208856047 14189.000050306155 6490.278052337848 8830.385502432551 7801.572569900729 9705.625273366933 6711.821760105823 6387.379252033365 7272.721633855104 5591.539819678098 2.7625156409501 2.537583654572455 1.1607317951124758 1.5792403858693993 1.395245821633058 1.7357696781860137 1.200353029139694 1.14232920769955 1.3006652672418582 1.0 12.44902991733773 -5.214442849710561 5.565314181403916 1.3423246783597516 2.682222587254945 0.8647915694991495 0.21121842965748625 0.06822760840412594 5.165805174062938 0.05507806855157024 0.1485485778020373 6.103193653636333e-06 5.214442849710561 1.3398979088951934 up ASSDLSIAS(ph)SEEDKLSQNACILESVSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSDLSIASSEEDKLSQNACILESVSEK 28 1 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 AS(0.012)S(0.012)DLS(0.128)IAS(0.408)S(0.408)EEDKLS(0.031)QNACILES(0.001)VS(0.001)EK 42.321000000000005 0.027275 3781000.0 6511.9 5688.5 3357.0 3897.3 5524.5 3942.6 5589.2 3692.7 3891.8 3819.8 True False 7614.236054112375 6253.216686013196 3437.043611493394 3678.9469162170776 4442.013882955077 3735.8431154493655 5059.750513696208 3595.7705377390653 3948.7102124377584 4512.29950247984 1.6874403061959413 1.385815964249845 0.7617055582424186 0.8153153207572383 0.9844235473540407 0.8279244570082827 1.1213241742742261 0.7968820632945409 0.8750993169375508 1.0 12.139647114012742 -5.071607519426761 3.520034660852987 0.8973715070615219 1.6499868839875833 0.8556175857539513 0.10795623420000798 0.0779019364689795 1.8158363198521508 0.02812737505190168 0.10233273952377239 8.4799341650284e-06 5.071607519426761 0.7526153769260614 ASSEDAGPS(ph)PQTR ddPTM_PC-9_AZD4547_30min_R2 2 ASSEDAGPSPQTR 13 0 Q5T5P2;Q5T5P2-2;Q5T5P2-7;Q5T5P2-10;Q5T5P2-3;Q5T5P2-4;Q5T5P2-8;Q5T5P2-6;Q5T5P2-9 Q5T5P2;Q5T5P2-9 KIAA1217 Sickle tail protein homolog 1 ASSEDAGPS(0.917)PQT(0.083)R;ASSEDAGPS(0.839)PQT(0.161)R 115.83 0.00028343 7235700.0 14498.3 17475.1 18745.9 29582.0 21191.6 22563.7 16118.599999999999 28656.0 14106.3 22192.4 True False 19108.457816626087 23123.5843307941 18497.317117646526 22762.32693734401 18249.51213364259 21152.78827206312 17553.124174134282 24227.873649371017 14851.930219417774 21415.450830840833 0.8922743661836716 1.0797617343405794 0.8637369936199595 1.0628927271782442 0.8521656759782564 0.9877349040721829 0.8196476605972575 1.13132680888884 0.6935147121922459 1.0 14.386364428227024 -6.2759371879989505 24.539010036423523 0.9195939436947181 0.9742497405058691 0.051326098895899785 0.12629733864878898 2282.5652999869408 3863465.105376026 0.03592409571240832 0.04093232314113391 5.297400546434848e-07 6.2759371879989505 0.05465579681115096 ASSEDAGPS(ph)PQTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSEDAGPSPQTR 13 0 Q5T5P2;Q5T5P2-2;Q5T5P2-7;Q5T5P2-10;Q5T5P2-3;Q5T5P2-4;Q5T5P2-8;Q5T5P2-6;Q5T5P2-9 Q5T5P2;Q5T5P2-9 KIAA1217 Sickle tail protein homolog 1 ASSEDAGPS(0.927)PQT(0.073)R 90.853 0.005404399999999999 3604300.0 8344.7 6028.2 7858.5 7273.7 9937.4 7130.1 5961.3 6451.8 6993.3 5381.3 True False 9757.292894662312 6626.639857014103 8045.876443527216 6866.17817065357 7990.237806222783 6756.185004176313 5396.6025079255005 6282.447086247163 7095.563782476226 6356.88709165264 1.5349168160426847 1.042434726537094 1.2656944078954024 1.0801164267444188 1.256941910564202 1.0628134347467015 0.848937920418925 0.9882898650971438 1.1162010084768625 1.0 12.634104748780063 -6.9107896633478 4.606091380572445 0.9832866445060358 1.2173319389711659 0.41871232327523056 0.1381328572763021 0.21777765205914754 8.226372553052167 0.048223558041806946 0.04219338146926836 1.228033846100645e-07 6.9107896633478 0.23404529446513012 ASSEDAGPS(ph)PQTR ddPTM_PC-9_Lapatinib_30min_R1 1 ASSEDAGPSPQTR 13 0 Q5T5P2;Q5T5P2-2;Q5T5P2-7;Q5T5P2-10;Q5T5P2-3;Q5T5P2-4;Q5T5P2-8;Q5T5P2-6;Q5T5P2-9 Q5T5P2;Q5T5P2-9 KIAA1217 Sickle tail protein homolog 1 ASSEDAGPS(0.778)PQT(0.222)R 96.135 0.0033399000000000002 3614500.0 10445.0 8503.7 9747.6 7711.8 8462.0 5308.1 10613.0 7030.1 8831.6 4883.4 True False 10296.052384621597 8484.010205115774 8946.189954824125 8278.95149781065 7964.2817969320995 5081.084936785458 11162.489210192178 7356.744110641819 7836.89220712909 5727.4891832785215 1.797655491813246 1.481279131855011 1.561974133612097 1.4454765836976449 1.3905363313795376 0.887140031904338 1.948932394805949 1.2844623316129393 1.3682945451925073 1.0 12.48368711357481 -1.5228787452844899 0.03840108812806979 7.401949186442436e-10 3.7036568922892443 0.2750177682204148 0.2595327772329727 1257.432206379124 3.6952652468323444 100.16267032646334 309.7189992567374 0.02999999999971317 1.5228787452844899 3.7036568915490493 ASSEDAGPSPQT(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSEDAGPSPQTR 13 0 Q5T5P2;Q5T5P2-2;Q5T5P2-7;Q5T5P2-10;Q5T5P2-3;Q5T5P2-4;Q5T5P2-8;Q5T5P2-6;Q5T5P2-9 Q5T5P2;Q5T5P2-9 KIAA1217 Sickle tail protein homolog 1 ASSEDAGPS(0.136)PQT(0.864)R 98.25299999999999 0.0068601 2966300.0 11143.0 12933.0 12004.0 10956.0 17396.0 12631.0 11559.0 10197.0 9741.0 7443.7 True False 13029.289815718017 14216.90276878063 12290.220885423514 10342.170839831244 13987.37867823089 11968.608124395316 10464.047840087036 9929.339554614578 9883.44369683853 8793.183885703223 1.4817488164784371 1.6168094462229765 1.3976986089653032 1.1761576892127217 1.5907069452934872 1.3611233746464682 1.1900180840185155 1.1292086784126762 1.1239891972358218 1.0 13.1021699237983 -7.499030290025206 0.5686852389081422 0.990464823804523 1.4955528795230162 0.66302424772741 0.11730041307238954 0.5316770321686278 0.35804604991705574 0.11817183494195811 0.0803147150028293 3.169346408127001e-08 7.499030290025206 0.5050880557184931 ASSES(ph)SYLSILPK ddPTM_PC-9_AZD4547_30min_R2 1 ASSESSYLSILPK 13 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 AS(0.014)S(0.229)ES(0.379)S(0.379)YLSILPK 198.57 6.6714e-07 2676700.0 14908.0 14063.0 21814.0 23952.0 18761.0 14346.0 13070.0 20425.0 15433.0 17277.0 True False 19648.433894336682 18608.5897330463 21524.732106985593 18430.236454711092 16156.358988432616 13448.942352141607 14233.204680055036 17268.78556980747 16248.756872906059 16672.137488709523 1.1785191855359114 1.116149008826742 1.2910601368038308 1.105451323634547 0.9690634448866442 0.8066717516724724 0.853712050401087 1.0357871377621497 0.9746054987796148 1.0 14.025151459679032 -6.190244068666025 3.161796100971957 0.9284473500005234 1.1878555737390877 0.7031714820090517 0.0754721677849748 0.14793074302751774 2.9057772803973188 0.025056235196094418 0.032792301915480326 6.452914804826146e-07 6.190244068666025 0.2594082237385643 ASSESS(ph)YLSILPK ddPTM_PC-9_AZD4547_30min_R2 2 ASSESSYLSILPK 13 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 AS(0.231)S(0.231)ES(0.231)S(0.305)Y(0.001)LS(0.001)ILPK;ASS(0.002)ES(0.09)S(0.706)Y(0.202)LS(0.001)ILPK 103.26 0.0015439 6170600.0 17131.7 16901.6 22265.7 34687.0 25374.0 20519.0 22868.0 28424.0 28054.0 28235.0 True False 22579.224238503346 22364.711671197823 21970.442269850068 26690.44805880777 21851.258087121652 19235.94368629539 24903.207698813967 24031.723918541375 29536.877166623875 27246.50124406514 0.8287017858273298 0.8208287541531347 0.8063582943382754 0.9795917582123139 0.8019840012258938 0.7059968365841242 0.9139965339306971 0.8820113710480896 1.0840612855956184 1.0 14.733783363130417 -8.0517731978436 2.296239672340859 1.0406619977398617 0.832891265723036 0.554251842286771 0.07159164922951393 0.24135253502486226 2.3207152044128656 0.061239081913089986 0.020065152813843332 8.876194336399271e-09 8.0517731978436 -0.20777073201682572 ASSESSY(ph)LSILPK ddPTM_PC-9_AZD4547_30min_R2 1 ASSESSYLSILPK 13 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 ASS(0.001)ES(0.007)S(0.048)Y(0.929)LS(0.014)ILPK 112.83 0.0005968 2404900.0 14847.0 20562.0 25441.0 37161.0 40448.0 34228.0 29908.0 37379.0 45533.0 36365.0 True False 19568.037163215504 27208.264388174484 25103.635717145906 28594.105581726737 34832.493383301655 32087.717749135863 32569.754060526833 31602.934433969793 47939.78142253812 35091.87241864457 0.5576230566944288 0.7753437623271004 0.7153689440580594 0.8148355619386807 0.9926085723711595 0.9143917248510064 0.9281281338302793 0.900577035529712 1.3661220709632858 1.0 15.098849308110944 -5.388393767433935 0.3643809313111852 1.1035616678484435 0.38453216221296366 0.6273064448852845 0.12373836930352028 2.7595043713714102 0.406932722803805 0.11936346148061745 0.8389631788486078 4.088897582081191e-06 5.388393767433935 -0.7190295056354798 ASSESSY(ph)LSILPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSESSYLSILPK 13 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 ASS(0.003)ES(0.021)S(0.176)Y(0.798)LS(0.002)ILPK 164.33 0.00047817 2033900.0 8138.5 5739.5 9008.3 11177.0 12857.0 11626.0 13926.0 13124.0 13695.0 11373.0 True False 9516.187307297949 6309.279628965937 9223.092036168 10550.788926322915 10337.763144746748 11016.312093596698 12606.828464491044 12779.508906027431 13895.263466605436 13434.834871381532 0.708321866133914 0.469620928680394 0.6865057981333842 0.7853307485600645 0.7694745222933801 0.8199812055050489 0.9383686949026607 0.9512218816511057 1.0342712507918275 1.0 13.713690968730598 -6.5458494196984125 0.5553197269326515 1.025724824919187 0.5608309023248527 0.8291986615654906 0.06743190065222011 0.37326055559766963 0.24727675600902166 0.054748896733407354 0.0823278562311729 2.845447521257478e-07 6.5458494196984125 -0.4648939225943344 ASSESSY(ph)LSILPK ddPTM_PC-9_Lapatinib_30min_R1 2 ASSESSYLSILPK 13 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 ASSES(0.034)S(0.127)Y(0.838)LS(0.001)ILPK;ASSES(0.02)S(0.102)Y(0.874)LS(0.004)ILPK 187.42 6.9355e-36 0.0 25462.0 17115.6 23923.0 15075.5 30645.0 23499.0 23504.0 17911.3 33088.0 18983.0 True False 25098.907210841076 17075.969879779317 21956.143285450522 16184.20256039375 28842.52135038811 22494.002548844506 24720.92211404476 18743.524386415393 29361.281007913305 22264.186256742454 1.127322010398658 0.7669703120008734 0.9861641935734954 0.7269164196599618 1.2954671245464218 1.0103222408154466 1.1103447406059277 0.8418688278238389 1.3187673094956065 1.0 14.442437262616313 -6.253952433254243 24.966867269371512 1.084642328237904 0.8982323936790446 0.24382152493797948 0.16683584222894746 853.6238198154725 2846594.7760890275 0.04669166372554893 0.05908747609057538 5.572467788676865e-07 6.253952433254243 -0.18640993455885946 ASSESSYLSILPKT(ph)PEGISEEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSESSYLSILPKTPEGISEEQR 23 1 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 ASSESSYLSILPKT(0.98)PEGIS(0.02)EEQR 104.96 1.8346e-06 5362100.0 6728.4 3604.5 5513.7 10075.0 9665.0 12435.0 11256.0 14848.0 10091.0 6422.4 True False 7867.385228042462 3962.330938689385 5645.167518823696 9510.530413590714 7771.212630783027 11782.886709433586 10189.750193617072 14458.255732756423 10238.561784703583 7586.730280309575 1.0369928727348185 0.5222712278269768 0.7440843828961514 1.2535743412777076 1.024316450388681 1.5530915524985274 1.3431016811106775 1.9057295038260482 1.3495354924210907 1.0 12.889262533314053 -6.191181014418205 1.1840232757986098 1.4796791255894937 0.7378012171791835 0.48287238242354913 0.27154630379283345 0.3553317742052164 1.0220141519128505 0.10646923702233856 0.1679476314481386 6.439008310018827e-07 6.191181014418205 -0.7418779084103102 ASSESSYLSILPKT(ph)PEGISEEQR ddPTM_PC-9_Lapatinib_30min_R1 2 ASSESSYLSILPKTPEGISEEQR 23 1 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 ASSESSYLSILPKT(0.977)PEGIS(0.023)EEQR;ASSESSYLSILPKT(0.83)PEGIS(0.17)EEQR 135.37 4.929800000000001e-07 12270300.0 47014.0 19333.2 31969.0 30251.0 31691.0 25662.0 19289.7 18833.2 28804.0 20504.0 True False 46343.57173868829 19288.435163228274 29340.63222390868 32475.759454377698 29826.997686903247 24564.49608104377 20288.42628077302 19708.259225976824 25559.79020043325 24048.089080137364 1.9271207614149262 0.8020776660861445 1.220081650817849 1.3504507300416317 1.2403063539688481 1.0214739308052936 0.843660642355585 0.8195353551918999 1.0628615901770126 1.0 14.553634638029571 -6.829953495936579 3.063559940806862 0.9175445337228179 1.2819739435203081 0.31697677304795124 0.2643825381114863 0.32795936419823385 6.22914054994772 0.09571692841308736 0.08558912347599149 1.47926677892839e-07 6.829953495936579 0.3644294097974903 ASSESSYLSILPKTPEGIS(ph)EEQR ddPTM_PC-9_AZD4547_30min_R2 2 ASSESSYLSILPKTPEGISEEQR 23 1 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 ASSESSYLSILPKT(0.143)PEGIS(0.857)EEQR;ASSESS(0.001)YLS(0.001)ILPKT(0.29)PEGIS(0.709)EEQR 130.29 3.7621e-07 17060700.0 22083.1 11859.3 22718.0 34831.0 35725.0 22288.0 18782.0 22721.9 21031.9 25658.5 True False 29105.0664429854 15692.586803748547 22416.744476322503 26801.25108358559 30765.200408387376 20894.327836646604 20453.561614444803 19210.752452318637 22143.60329652517 24760.20372483956 1.1754776643371092 0.6337826206173605 0.9053537977893903 1.0824325753304864 1.2425261419607616 0.8438673634855964 0.8260659662475106 0.7758721481377115 0.894322338483451 1.0 14.595735564521926 ASSESSYLSILPKTPEGIS(ph)EEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSESSYLSILPKTPEGISEEQR 23 1 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 ASSESSYLSILPKT(0.286)PEGIS(0.714)EEQR 127.4 2.1414e-07 5569500.0 9159.5 4853.8 6926.2 12671.0 13408.0 14386.0 13278.0 20815.0 12503.0 7403.9 True False 10710.022441628753 5335.653186353317 7091.346875759775 11961.084949936265 10780.798650133347 13631.572834894383 12020.211715604772 20268.628305315528 12685.83272164789 8746.168460759842 1.224538778286726 0.6100560731584367 0.8107946819885172 1.3675799870080618 1.2326310313484108 1.5585765236575504 1.3743402919271568 2.317429443104352 1.4504445893723137 1.0 13.094435421231472 -6.239470438163959 1.1469835000671504 1.6268103802300984 0.8549953518185324 0.3486094519794233 0.35640408228310966 0.46602307447693125 1.2663684533207078 0.14675958516810808 0.22264906804364595 5.761420344316081e-07 6.239470438163959 -0.771815028411566 ASSGDQGS(ph)PPCFLR ddPTM_PC-9_AZD4547_30min_R2 1 ASSGDQGSPPCFLR 14 0 A6NN50;O75147-2;O75147-1;O75147-4;O75147 A6NN50 OBSL1 Obscurin-like protein 1 1 ASSGDQGS(1)PPCFLR 149.6 0.00022569999999999996 21893000.0 67682.0 69214.0 88925.0 123830.0 113200.0 90901.0 70696.0 110010.0 73375.0 81071.0 True False 89203.468126945 91586.0719464599 87745.79639743717 95282.90665442866 97484.13397423226 85216.9461000991 76987.80704370077 93010.48227831197 77253.45270196859 78232.72896609202 1.1402320909143788 1.1706874240083782 1.1215995857113503 1.217941747829436 1.2460786586709032 1.0892748754429136 0.9840869423981 1.1888947695870995 0.9874825245512288 1.0 16.255484670442655 -6.946183695853766 7.511617330118161 1.053137739763948 1.177292377212967 0.5107263218126475 0.06422465691203165 0.20495018462569792 24.149674043368524 0.022350450771159294 0.01966076667506312 1.1319214870966364e-07 6.946183695853766 0.124154637449019 ASSGDQGS(ph)PPCFLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSGDQGSPPCFLR 14 0 A6NN50;O75147-2;O75147-1;O75147-4;O75147 A6NN50 OBSL1 Obscurin-like protein 1 1 ASSGDQGS(1)PPCFLR 153.41 0.00026327 12592000.0 57030.0 48930.0 65315.0 80486.0 86360.0 64840.0 73435.0 65704.0 60923.0 53132.0 True False 66684.05260615608 53787.447032895434 66872.35730851692 75976.6303591325 69438.37794044729 61439.6762557036 66478.70517664083 63979.33961914244 61813.88362000756 62764.411007319395 1.0624500658243983 0.8569736602263806 1.0654502485607404 1.2105049524048324 1.1063336184633294 0.9788935364746543 1.059178348202587 1.0193569666682822 0.9848556312079311 1.0 15.937659126290798 -10.435755184247471 14.040429772044805 0.9999998229257986 1.0390788933289143 0.016994692237506825 0.08698818862310208 0.0 0.0 0.09017290572894365 0.021870142052311685 3.6664419707608854e-11 10.435755184247471 0.039079070403115757 ASSGDQGS(ph)PPCFLR ddPTM_PC-9_Lapatinib_30min_R1 1 ASSGDQGSPPCFLR 14 0 A6NN50;O75147-2;O75147-1;O75147-4;O75147 A6NN50 OBSL1 Obscurin-like protein 1 1 ASSGDQGS(1)PPCFLR 148.18 0.00021187 21631000.0 104600.0 79282.0 92226.0 84779.0 86313.0 84552.0 71447.0 62256.0 83597.0 68650.0 True False 103108.38481870948 79098.42740007151 84643.53428265502 91013.93047445329 81236.2390378871 80935.90806033881 75146.1760671441 65148.641036701796 74181.42554456387 80516.06102962492 1.2805940019938629 0.9823931571983904 1.0512627319350787 1.130382302742875 1.008944526086506 1.0052144506989658 0.9333066608846521 0.8091384526713389 0.9213245729602905 1.0 16.29698897465982 -6.854088310445686 1.2847508546239632 0.8971241592406347 1.0994463237327565 0.49631999043044517 0.08526540808313304 0.36696888969476 1.2638274868820814 0.042715026863393166 0.03539106918497775 1.399302756178468e-07 6.854088310445686 0.20232216449212181 ASSHS(ph)SQTQGGGSVTK ddPTM_PC-9_AZD4547_30min_R2 3 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 AS(0.003)S(0.003)HS(0.859)S(0.134)QTQGGGSVTK;AS(0.046)S(0.046)HS(0.779)S(0.128)QTQGGGSVTK;AS(0.046)S(0.349)HS(0.534)S(0.07)QT(0.001)QGGGSVTK 225.13 1.9660999999999997e-92 878181000.0 15377.1 22650.7 132638.8 395516.8 209814.4 146358.7 56563.82 228934.8 89746.5 147918.3 True False 20266.69793645055 29972.0958164198 130879.92284734758 304336.5124336459 180685.29222016898 137206.86735218106 61597.890401361146 193558.18705834768 94490.31676888901 142739.72533982675 0.14198358507556835 0.20997725577139728 0.9169130915430584 2.1321080148437903 1.2658374659892582 0.9612381348326587 0.43153992523603596 1.3560218544454614 0.6619763106866834 1.0 17.123027375998547 -5.304314952411181 4.361337878861924 1.1274353022341106 0.16206777754012516 0.42479619091236076 0.4290381197889583 0.19283259585293805 8.282143002915104 0.12079902011070263 0.28294925220955464 4.962323209042612e-06 5.304314952411181 -0.9653675246939855 ASSHS(ph)SQTQGGGSVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 ASSHS(0.868)S(0.132)QTQGGGSVTK;AS(0.054)S(0.236)HS(0.656)S(0.054)QT(0.001)QGGGSVTK;ASSHS(0.5)S(0.5)QTQGGGSVTK;AS(0.127)S(0.127)HS(0.539)S(0.198)QT(0.009)QGGGSVTK;AS(0.004)S(0.013)HS(0.747)S(0.236)QTQGGGSVTK;ASS(0.001)HS(0.497)S(0.497)QT(0.004)QGGGSVTK;ASS(0.001)HS(0.929)S(0.07)QTQGGGSVTK;ASSHS(0.5)S(0.5)QTQGGGSVTK 311.43 1.6847999999999995e-129 432232900.0 69511.3 109688.6 416640.0 338421.0 592455.0 618850.0 372775.0 347583.8 482182.0 249631.6 True False 81278.1901792443 120577.75930129708 426574.2777159986 319460.3685456856 476367.69572380406 586396.4165768378 337463.0533427143 338460.09354547877 489232.9995512782 294887.8329973418 0.27562408849868336 0.4088936395771337 1.4465645238060527 1.0833284143960096 1.6154199747132265 1.9885405600376997 1.1443776771412482 1.1477587600181853 1.6590477625968658 1.0 18.169806772806233 -5.236726453654614 5.285036249342702 1.4030591678789717 0.3199393495171775 0.6697174483180159 0.29306055164826583 0.10426737219158017 8.897626640936682 0.07774610882655059 0.2027891241019518 5.7979377251303604e-06 5.236726453654614 -1.0831198183617943 ASSHS(ph)SQTQGGGSVTK ddPTM_PC-9_Lapatinib_30min_R1 1 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 AS(0.004)S(0.05)HS(0.67)S(0.245)QT(0.032)QGGGSVTK 128.82 1.9598e-05 12479000.0 10524.0 6445.3 32821.0 11310.0 20404.0 40697.0 18301.0 23913.0 61899.0 19307.0 True False 10373.92583013477 6430.376303848048 30122.58407272381 12141.775129053984 19203.876835807434 38956.48417934057 19248.536232519276 25024.085278698436 54927.2827946333 22644.189225039587 0.4581275013663747 0.2839746762377979 1.3302566841039614 0.5361982718121698 0.8480708514205529 1.720374432141872 0.8500430746813645 1.105099636379438 2.4256678942558727 1.0 14.466853264181237 -5.89359543667769 0.49043154139081335 1.4997472324293737 0.21256881752377094 0.3495575392096778 0.49106969755042823 2.037841340973423 0.7948166469080464 0.3853080850352117 1.360908287648966 1.277628418501566e-06 5.89359543667769 -1.2871784149056027 ASSHS(ph)SQTQGGGSVTKK ddPTM_PC-9_AZD4547_30min_R2 1 ASSHSSQTQGGGSVTKK 17 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 AS(0.007)S(0.006)HS(0.478)S(0.478)QT(0.031)QGGGSVTKK 71.545 0.0060624 10389000.0 1270.0 839.64 4485.7 21485.0 13121.0 7423.5 3218.1 8234.5 4785.5 9507.9 True False 1673.8335823589753 1111.0372099448903 4426.216687095689 16531.965189941053 11299.375634946135 6959.307371471016 3504.5046657142393 6962.047234985536 5038.451760208119 9175.031314979524 0.1824335552540521 0.12109356053433479 0.4824197907498441 1.801842917195313 1.2315353754159204 0.758505026583285 0.3819610577233284 0.7588036482904444 0.5491481813236038 1.0 13.16349736663849 -5.529746743689027 24.99595912040821 0.9177098757510919 0.189261643606942 0.4217014449384294 0.3694732393354055 170.19523933363337 619420.7341045387 0.11188106511417918 0.19434763407756908 2.9529307091161266e-06 5.529746743689027 -0.7284482321441499 ASSHSS(ph)QTQGGGSVTK ddPTM_PC-9_AZD4547_30min_R2 3 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 AS(0.056)S(0.226)HS(0.276)S(0.433)QT(0.009)QGGGSVTK;AS(0.046)S(0.105)HS(0.391)S(0.422)QT(0.036)QGGGSVTK;ASSHS(0.013)S(0.986)QTQGGGSVTK 131.37 5.9108e-06 29471500.0 40303.9 39612.0 115093.0 255136.0 157193.0 127964.0 60585.0 155128.0 87354.0 133641.0 True False 53119.7018268015 52415.8043451205 113566.79161956976 196318.3370119058 135369.46529868813 119962.39085106966 65976.94763130338 131156.53208681 91971.35410327445 128962.26926715481 0.41190110974831046 0.4064429436840733 0.8806202951059104 1.5222928235328888 1.0496827178053167 0.9302130889350183 0.5115988420971973 1.017014765885591 0.7131648243002691 1.0 16.976589509827136 -5.292091546461023 5.051648900196379 0.9639742810060938 0.40401032656677466 0.4449213519382851 0.24384466502218197 0.16990611690838997 11.996399601766743 0.0693480972633974 0.15902833041192213 5.1039740017235565e-06 5.292091546461023 -0.5599639544393191 ASSHSS(ph)QTQGGGSVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 AS(0.002)S(0.002)HS(0.01)S(0.98)QT(0.006)QGGGSVTK 108.47 0.00044879 218500000.0 18862.0 22322.0 71737.0 64520.0 85383.0 75861.0 65538.0 48216.0 59888.0 39140.0 True False 22054.964058518635 24537.98063904132 73447.48214408764 60905.15357666226 68652.81407699388 71882.7156143419 59329.76618596967 46950.38108907482 60763.74870303522 46235.77216793045 0.47701083002169814 0.5307141957079953 1.5885423493593447 1.3172734166837734 1.4848419493816107 1.554699148383649 1.2832005048056996 1.0154557583368322 1.3142150731762083 1.0 15.496721862352963 -5.248933484365991 24.611589527673203 1.3332198290743889 0.5038622813663907 0.7504060446832792 0.1880959530424231 296.2238684502673 582965.0260124909 0.04947731856081378 0.1288806080139261 5.637239880008665e-06 5.248933484365991 -0.8293575477079982 ASSHSS(ph)QTQGGGSVTK ddPTM_PC-9_Lapatinib_30min_R1 1 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 AS(0.013)S(0.013)HS(0.195)S(0.775)QT(0.005)QGGGSVTK 108.47 0.00044879 7687300.0 25580.0 13393.0 49259.0 20992.0 36119.0 40915.0 27253.0 30558.0 58464.0 22062.0 True False 25215.22450920251 13361.989331363471 45209.11516523877 22535.82170725917 33994.55143268618 39165.16082752341 28664.026990046856 31977.8362374636 51879.16866678688 25875.387304232838 0.9744868439158655 0.5163976552025423 1.747186027930226 0.8709365947760185 1.3137794241682776 1.5136067478733568 1.1077719012676512 1.235839906915422 2.0049620149376546 1.0 14.659292836662445 -5.250408086486271 24.990559071567755 1.3365779495540253 0.7454422379540435 0.3370799500989914 0.33833788536648846 801.5800742189261 1815910.8154824665 0.08236333478748793 0.21342601690951038 5.618131671752507e-06 5.250408086486271 -0.5911357115999818 ASSHSSQT(ph)QGGGSVTK ddPTM_PC-9_AZD4547_30min_R2 1 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 AS(0.002)S(0.272)HS(0.012)S(0.026)QT(0.689)QGGGSVTK 156.72 0.00010502 32216000.0 0.0 1234.5 30377.0 118920.0 62200.0 44691.0 10120.0 65153.0 23955.0 45166.0 True False 0.0 1633.5279830367383 29974.181132020793 91504.83129568491 53564.60365015238 41896.46470511365 11020.66039496227 55085.10091699712 25221.212394898223 43584.752087460445 0.0 0.037479345523378865 0.6877217305692676 2.099468894811296 1.2289757560778507 0.9612642655633569 0.2528558697052442 1.2638617470270155 0.5786705484589528 1.0 15.411535883007664 -5.373505068093721 4.094869092241157 1.0560403423962461 0.019695303218479142 0.44297115216108907 0.4561249485446019 0.21155049772714263 6.00688126305854 0.12902678819025598 0.2896626733768032 4.231505716403625e-06 5.373505068093721 -1.0363450391777669 ASSHSSQT(ph)QGGGSVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 ASSHSS(0.005)QT(0.774)QGGGS(0.219)VT(0.002)K;ASSHSSQT(0.598)QGGGS(0.391)VT(0.011)K 201.75 3.3518e-12 5917100.0 3678.1 2308.0 26146.0 8604.9 19087.6 21566.0 7873.5 6821.900000000001 14175.8 6859.9 True False 4300.729684213626 2537.122986959383 26769.419799257175 8122.795350462203 15347.52180148308 20435.040995226762 7127.665080796376 6642.832353400524 14383.094257021217 8103.545567061477 0.5307219720827909 0.31308801387778207 3.3034206542956914 1.002375476665297 1.8939267601414165 2.5217407400396654 0.8795736411686549 0.8197439378142918 1.774913726095927 1.0 12.984337557205732 ASSHSSQTQGGGS(ph)VTK ddPTM_PC-9_AZD4547_30min_R2 2 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 ASSHSSQT(0.018)QGGGS(0.722)VT(0.259)K;ASSHSSQT(0.042)QGGGS(0.931)VT(0.027)K 178.23 7.291799999999999e-06 46689000.0 6854.530000000001 5071.2 27271.3 68863.0 38187.3 23571.6 11844.099999999999 38946.2 16591.7 28024.4 True False 9034.127956918952 6710.366227278987 26909.664743249126 52987.699272744234 32885.65255577916 22097.66412573129 12898.201954937998 32927.95968464312 17468.70338937311 27043.27428596349 0.3340619135608152 0.24813438477610414 0.9950594169440602 1.9593670023990737 1.2160381249709875 0.8171223607047035 0.4769467564670106 1.2176025482880974 0.645953711250122 1.0 14.722982217195499 -5.281193557260961 6.802560237382814 1.0611386877007807 0.28894940292867627 0.38412875578759964 0.37936677832425214 0.16597728806226852 36.59878883369356 0.10782726050658281 0.23976574315719784 5.233671292569108e-06 5.281193557260961 -0.7721892847721044 ASSHSSQTQGGGS(ph)VTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 ASSHSSQTQGGGS(0.989)VT(0.011)K 129.89 9.931600000000001e-05 0.0 2372.1 2539.5 8147.7 6356.9 10747.0 9643.4 4685.7 4006.1 4829.4 3472.8 True False 2773.6496788894124 2791.6047770291834 8341.97206832432 6000.743502347871 8641.202497985016 9137.683127764527 4241.836574469749 3900.9441198138134 4900.020838672827 4102.3911493303285 0.6761056120507136 0.6804823517340327 2.033441416157028 1.46274289406251 2.106381908364735 2.227404163851162 1.0339912553590078 0.9508952164277658 1.19443043344921 1.0 12.002249339204317 ASSHSSQTQGGGS(ph)VTK ddPTM_PC-9_Lapatinib_30min_R1 2 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 ASSHSSQTQGGGS(0.83)VT(0.17)K;ASSHSSQT(0.003)QGGGS(0.914)VT(0.082)K 119.72 5.8932e-05 24350000.0 29419.0 21579.6 161353.0 31605.0 55153.0 75839.0 44223.0 46441.0 128705.0 37827.0 True False 28999.47966521615 21529.633762046677 148087.17918059163 33929.33713118931 51909.00897496998 72595.54275934373 46512.650555199165 48598.818401205805 114208.88757626574 44365.3465486908 0.6536515979513273 0.48528041448787024 3.3379020046212533 0.7647711506987102 1.17003501636125 1.6363118606471472 1.0484004786066914 1.0954229411432364 2.574281425953067 1.0 15.43714561733228 ASSHSSQTQGGGSVT(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 ASSHSSQT(0.002)QGGGS(0.371)VT(0.627)K 96.455 0.0048714 1394700.0 9519.6 8668.0 19080.0 11283.0 16350.0 15990.0 12009.0 13131.0 13307.0 9897.6 True False 11131.080259329556 9528.501755183683 19534.939561302956 10650.850089979544 13146.334869457049 15151.45625121376 10871.42058236917 12786.325163444537 13501.589700629325 11691.956530641506 0.9520288781572149 0.8149621263312103 1.67080158997402 0.910955327456658 1.1243913569986344 1.295887152120847 0.9298204756302395 1.0936001284246124 1.1547759064315073 1.0 13.5132287500407 -9.907245102005373 11.5445270038662 1.0000033486973106 1.108296675926796 0.018125786055583015 0.23140861170823063 0.0 0.0 0.21805488027996708 0.052886076680924585 1.2380976463495033e-10 9.907245102005373 0.10829332722948548 ASSKGGGGY(ph)TCQSGSGWDEFTK ddPTM_PC-9_Lapatinib_30min_R1 1 ASSKGGGGYTCQSGSGWDEFTK 22 1 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 AS(0.021)S(0.411)KGGGGY(0.51)T(0.058)CQSGSGWDEFTK 91.337 0.00052132 0.0 13857.0 10207.0 13285.0 11433.0 11514.0 15547.0 13458.0 11644.0 17266.0 16096.0 True False 13659.396638937424 10183.366318616212 12192.758581582995 12273.820959369948 10836.769157394969 14882.091051827116 14154.789389500256 12185.022748511878 15321.321260959603 18878.17215342815 0.7235550416599505 0.539425439912994 0.6458654197286188 0.6501593935905021 0.5740369919990947 0.7883226686819162 0.7497966050134701 0.6454556431354059 0.8115892331333229 1.0 14.20443146454352 -9.53844024220228 0.28818008211399126 1.105365795846405 0.6036778109946278 0.6963389119532721 0.07006945876159129 3.320181011658907 0.4157945283619048 0.4723362824879077 0.09524992520980169 2.8944080527300724e-10 9.53844024220228 -0.5016879848517771 ASSKGGGGYT(ph)CQSGSGWDEFTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSKGGGGYTCQSGSGWDEFTK 22 1 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 AS(0.021)S(0.021)KGGGGY(0.362)T(0.59)CQS(0.004)GS(0.002)GWDEFTK 52.99 0.015429 7426700.0 10485.0 6502.9 6685.6 14551.0 12520.0 20704.0 14701.0 19256.0 16560.0 13072.0 True False 12259.903411810415 7148.464935831097 6845.010059279191 13735.754644978499 10066.795875572003 19618.245792691043 13308.414853976941 18750.55040341847 16802.158671557958 15441.850122104932 0.7939400599582574 0.4629280092285124 0.4432765507470244 0.8895148273273183 0.6519164346221334 1.2704595393402778 0.8618406958196033 1.2142683846268623 1.0880923295263532 1.0 13.91455799498448 -6.440579188633345 1.454824892542185 1.0872882275192783 0.5809704775056551 0.5827453201934271 0.17629769296370987 0.26766340167402236 1.150741356397049 0.06754982613001921 0.08018989495535686 3.6259416531648474e-07 6.440579188633345 -0.5063177500136232 ASSLSES(ph)SPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSLSESSPPK 11 0 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VRN8;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 ASS(0.001)LS(0.008)ES(0.977)S(0.014)PPK 160.72 0.001234 703150000.0 162010.0 170830.0 145260.0 195590.0 195000.0 175930.0 121930.0 169940.0 126330.0 106510.0 True False 189435.09315664327 187788.87342386122 148723.54930161755 184631.72641133599 156791.14981921256 166703.9210929353 110379.90770324518 165479.25506631352 128177.3372571203 125819.41986730394 1.5056109252167267 1.4925269375897112 1.182039699900616 1.467434253043439 1.2461601713358168 1.3249458729721566 0.8772883217841719 1.3152123514862573 1.0187404884897988 1.0 16.940995089690382 -5.29647886850473 0.2526426740970291 0.9729556193489842 1.8307033749549029 0.549604777956533 0.1408288191767694 5.88678340480523 0.4001566165684548 0.20798634408934694 1.557556915632996 5.05267229162971e-06 5.29647886850473 0.8577477556059186 ASSLSES(ph)SPPK ddPTM_PC-9_Lapatinib_30min_R1 1 ASSLSESSPPK 11 0 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VRN8;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 ASS(0.001)LS(0.045)ES(0.477)S(0.477)PPK 72.29 0.027601999999999998 5258500.0 36258.0 31265.0 31248.0 28983.0 29683.0 23297.0 26838.0 27116.0 34846.0 23984.0 True False 35740.95427109713 31192.60781341587 28678.910060768187 31114.50650445371 27937.104299023347 22300.641617959503 28227.54032065747 28375.908351824808 30921.2765353526 28129.60244332883 1.2705815641405696 1.1088890387362533 1.0195277419418216 1.1061125576565969 0.9931567413832706 0.7927819692044132 1.003481665890087 1.0087561105419887 1.0992432828600405 1.0 14.779801542685853 -3.7496939097180957 0.7691778694745759 0.9857721753127469 2.381982934010544 0.5314294415306042 0.07907148739286522 9.225117672440144 1.264865660723495 0.031659167732816955 16.018517676541965 0.00017795331812233618 3.7496939097180957 1.396210758697797 ASSLSESS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASSLSESSPPK 11 0 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VRN8;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 AS(0.002)S(0.002)LS(0.018)ES(0.281)S(0.698)PPK;ASSLSES(0.08)S(0.92)PPK;ASSLS(0.001)ES(0.091)S(0.909)PPK 166.11 0.00010194 483578100.0 299204.0 307534.0 230883.0 309999.0 314821.0 268585.0 334006.0 330947.0 262996.0 236561.0 True False 349853.32765162754 338063.94309859985 236388.1263486535 292630.7610603179 253134.08501145846 254499.92978312998 302366.53368596797 322259.9919173322 266841.81896045076 279447.6366841537 1.2519459166049418 1.209757746066385 0.8459120612132128 1.0471756516984414 0.9058372724674849 0.9107249315218904 1.0820149967047974 1.153203497231817 0.9548902331997509 1.0 18.092218448476814 -5.130996031137254 6.7871513715305785 0.9931427549317464 1.2407927168959756 0.5613325464738124 0.08621549065314614 0.1772448586196973 8.838128923467474 0.02302409048188802 0.062447977668307425 7.396120340785751e-06 5.130996031137254 0.24764996196422917 ASSPAES(ph)SPEDSGYMR ddPTM_PC-9_AZD4547_30min_R2 1 ASSPAESSPEDSGYMR 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 AS(0.024)S(0.234)PAES(0.467)S(0.275)PEDSGYMR 196.97 6.6301e-12 9527100.0 17572.0 18489.0 23528.0 33316.0 28933.0 20572.0 19631.0 25262.0 15875.0 20403.0 True False 23159.53047969441 24465.207677898954 23216.003347077905 25635.51092706894 24916.15236993343 19285.629587916996 21378.120969713873 21358.33836300986 16714.120090545162 19688.697180189873 1.1762855748016063 1.2426016538318772 1.1791538634885956 1.3020420138749738 1.2655053882896452 0.9795279703586264 1.085806784169744 1.0848020144522272 0.8489195571234833 1.0 14.265080029444864 -6.761450467411776 24.999999999757776 1.0104860890682683 1.234475742533147 0.728852739705431 0.07099920968713448 0.1680746997612457 375451.583393741 0.024358004210332563 0.022880226406829494 1.7320065600284101e-07 6.761450467411776 0.22398965346487865 ASSPAES(ph)SPEDSGYMR ddPTM_PC-9_Lapatinib_30min_R1 2 ASSPAESSPEDSGYMR 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 AS(0.001)S(0.065)PAES(0.718)S(0.216)PEDSGYMR;ASS(0.003)PAES(0.927)S(0.07)PEDSGYMR 258.42 1.4868e-57 11454000.0 36023.0 32295.0 36864.0 32973.0 26617.0 33189.0 27155.0 25273.0 34074.0 23679.0 True False 35509.30541419086 32220.222911698904 33833.18421915511 35397.94441470352 25051.44039103543 31769.583837337777 28560.953029564545 26447.275843622545 30236.227304873017 27771.883599715795 1.278606302906809 1.160174202661163 1.2182531335217517 1.2745964560742205 0.9020432590064505 1.1439477528871285 1.0284125283405994 0.9523040001468678 1.088735202144605 1.0 14.761337409346195 -6.24825530185155 24.99907085226662 1.0235496230858268 1.2266655530117265 0.6919941314798266 0.0697495072067422 460.29282923373614 872786.9056618831 0.019971302953960195 0.025618876716810866 5.646049718119321e-07 6.24825530185155 0.20311592992589977 ASSPAESS(ph)PEDSGYMR ddPTM_PC-9_Lapatinib_30min_R1 1 ASSPAESSPEDSGYMR 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 ASS(0.019)PAES(0.404)S(0.568)PEDS(0.009)GYMR 135.61 8.164500000000001e-06 3304100.0 13215.0 10273.0 12344.0 18028.0 14915.0 12859.0 9957.2 10947.0 13587.0 13060.0 True False 13026.551676665804 10249.213499671234 11329.123969217952 19353.839259645007 14037.72902401823 12309.050545793074 10472.73509504622 11455.63758398829 12056.688982547092 15317.40359864387 0.8504412378230415 0.6691221154855937 0.739624303574594 1.263519573340648 0.9164561691944361 0.8035990216307194 0.6837147710838818 0.7478837722211953 0.7871235425052411 1.0 13.902884151171786 -6.873897064207055 5.663441495660401 0.778618531968386 0.8878468856705454 0.05067551133333348 0.16501968905822964 0.6079681715662841 27.916145047213544 0.06316581572977309 0.05575013046701174 1.3369123518535403e-07 6.873897064207055 0.10922835370215933 ASSPGYIDSPT(ph)YSR ddPTM_PC-9_AZD4547_30min_R2 2 ASSPGYIDSPTYSR 14 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 ASS(0.002)PGYIDS(0.329)PT(0.654)YS(0.015)R;ASSPGYIDS(0.21)PT(0.789)YSR 162.7 0.0013510999999999998 6956200.0 15075.099999999999 10868.6 17380.3 28021.0 18661.5 18580.1 18965.0 21653.0 14934.3 15486.8 True False 19868.668218440773 14381.662402942975 17149.82586591371 21561.191370134427 16070.672845937605 17418.283409802476 20652.848259926828 18307.0263864402 15723.69660902227 14944.611845815045 1.329487070218195 0.9623309425042235 1.1475591365537001 1.442740138893084 1.0753489626723154 1.1655226371556873 1.3819594963726185 1.2249917612658998 1.0521314819846186 1.0 13.867337806147932 -8.353131382306282 4.085890308304799 1.0065175710045602 1.2121709775338525 0.24192572251597533 0.1355857428794993 0.34327128758377934 9.704659985818926 0.1306519775658813 0.03472816906373287 4.43474464211704e-09 8.353131382306282 0.20565340652929232 ASSPHGLGSPLVAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 ASSPHGLGSPLVASPR 16 0 Q8IZW8 Q8IZW8 TNS4 Tensin-4 1 ASSPHGLGSPLVAS(1)PR 77.969 0.0057618 4095200.0 22436.0 24773.0 28161.0 35520.0 30007.0 31676.0 30626.0 36777.0 33603.0 30910.0 True False 29570.181302209417 32780.387787581305 27787.56673992947 27331.412778529495 25841.04600852287 29695.294712563613 33351.65466957654 31093.959701386004 35379.18597811587 29827.850308271787 0.9913614624118281 1.0989859292169883 0.9315980351498374 0.9163051475737765 0.8663395364216607 0.9955559789143968 1.1181380597289488 1.042447222311663 1.1861124959549834 1.0 14.864372386007352 -7.131879715764458 4.904758161742303 1.0894791409823947 0.9616985307438842 0.40253182704340473 0.07237870882612576 0.24649298709382444 8.779723756862685 0.029659610535895137 0.02283221413439096 7.381086318484598e-08 7.131879715764458 -0.1277806102385105 ASSPS(ph)PLTIGTPESQR ddPTM_PC-9_AZD4547_30min_R2 3 ASSPSPLTIGTPESQR 16 0 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 ASS(0.011)PS(0.98)PLT(0.008)IGTPESQR;AS(0.004)S(0.066)PS(0.824)PLT(0.104)IGT(0.001)PESQR;ASSPS(0.876)PLT(0.124)IGTPESQR 126.07 2.9498e-05 49161600.0 50663.0 53887.4 79249.0 94367.0 96452.0 85026.0 68882.0 101841.0 85787.0 87349.0 True False 66772.78014413605 71305.44822445838 78198.10647962331 72612.14610561625 83061.3046827089 79709.31077883672 75012.36455788468 86103.81352336652 90321.52568236849 84290.93809696643 0.7921703287644292 0.8459444138874118 0.9277166471876958 0.8614466482990715 0.98541203310796 0.9456450785627856 0.8899220515447592 1.0215073585290342 1.0715449100645267 1.0 16.3630899186018 -2.137839733926647 0.22569204805475732 1.0359766460812603 3.4898683419908104e-10 0.687453211688625 0.04638051014338849 23.304281199743123 0.38512723103260166 0.0736524759041011 8.371636338254566 0.0072804842396526825 2.137839733926647 -1.0359766457322734 ASSPS(ph)PLTIGTPESQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ASSPSPLTIGTPESQR 16 0 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 ASS(0.001)PS(0.562)PLT(0.422)IGT(0.016)PESQR;ASS(0.004)PS(0.995)PLTIGTPESQR;ASS(0.006)PS(0.989)PLT(0.005)IGTPESQR;ASS(0.004)PS(0.758)PLT(0.237)IGT(0.001)PESQR 217.79 3.6756e-22 51605800.0 99420.0 125661.0 131881.0 134795.0 155470.0 98572.0 117974.0 94747.0 91878.0 78674.0 True False 116249.84236549251 138135.7936153826 135025.54320147785 127242.87316128638 125006.76955073304 93402.71079391136 106798.6486622048 92259.99164274464 93221.54193390108 92936.97341695851 1.2508460098430538 1.4863384134066981 1.4528721803290325 1.3691308042754484 1.3450703735519178 1.0050113249854107 1.1491513521002708 0.9927156894686401 1.0030619516267854 1.0 16.503965042394185 -6.706481723086212 4.75589063208691 1.0361324778646865 1.395515042464123 0.8548381268570101 0.07231335406141505 0.07406369687725453 3.4546475007269106 0.024886396348071757 0.024322773235197777 1.9657047038497928e-07 6.706481723086212 0.3593825645994364 ASSPS(ph)PLTIGTPESQR ddPTM_PC-9_Lapatinib_30min_R1 4 ASSPSPLTIGTPESQR 16 0 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 ASS(0.002)PS(0.997)PLT(0.001)IGTPESQR;AS(0.023)S(0.12)PS(0.851)PLT(0.006)IGTPESQR;ASS(0.002)PS(0.997)PLT(0.001)IGTPESQR;AS(0.008)S(0.029)PS(0.69)PLT(0.265)IGT(0.009)PES(0.001)QR 205.66 5.9848e-17 56136900.0 86171.0 93352.0 117521.0 95048.0 105661.0 111207.0 90129.0 87349.0 91874.0 69300.9 True False 84942.18573817408 93135.84917952958 107858.87702417866 102038.14699083309 99446.22771751854 106450.93584617869 94795.43861541615 91407.55342320187 81526.18264388994 81279.46822735507 1.0450632563265996 1.1458717830068699 1.3270125823470647 1.2553988013973199 1.2235098221773226 1.3096903580669836 1.1662900937079728 1.124608162636061 1.0030353842355952 1.0 16.3106033428275 -8.011020370731188 1.883234160137923 0.9958575641555598 1.220944702656847 0.5423975956518858 0.07664507030488149 0.28749918439413896 1.8446336053176449 0.07029635020277042 0.023266703210536633 9.749439065675412e-09 8.011020370731188 0.22508713850128714 ASSQALGT(ph)IPK ddPTM_PC-9_Lapatinib_30min_R1 1 ASSQALGTIPK 11 0 F8W0I9;F8VVA6;F8VP44;F8W126;Q96EZ8-3;Q96EZ8;Q96EZ8-2 F8W0I9 MCRS1 Microspherule protein 1 1 AS(0.036)S(0.047)QALGT(0.917)IPK 80.455 0.039486 3235300.0 38897.0 38808.0 28422.0 35994.0 25273.0 21647.0 29588.0 30600.0 30526.0 28835.0 True False 38342.32164716382 38718.142460356416 26085.25287209274 38641.1188324641 23786.491828629758 20721.208271621643 31119.921864804128 32021.787710792134 27087.840426969364 33819.09132977766 1.1337478370805152 1.1448605192495267 0.7713173786288195 1.1425830001068258 0.7033450898098432 0.6127074222534374 0.9201879956308313 0.9468553545256552 0.800962987527656 1.0 15.045550276682476 -5.125451040339324 1.1949494949974242 0.8440841321018075 1.2248516287268656 0.31716041486732205 0.15022697506308083 1.0820488853643508 1.9654886709016945 0.04861675812029687 0.44165040398654126 7.491158044106227e-06 5.125451040339324 0.38076749662505804 ASSRVS(ph)GSFPEDSSK ddPTM_PC-9_Lapatinib_30min_R1 1 ASSRVSGSFPEDSSK 15 1 O15400-2;O15400 O15400-2 STX7 Syntaxin-7 1 AS(0.008)S(0.008)RVS(0.965)GS(0.019)FPEDSSK 87.287 0.038595 0.0 11313.0 10081.0 8746.3 10350.0 10576.0 11205.0 11558.0 8359.7 17821.0 7630.4 True False 11151.674545449885 10057.658063874791 8027.212975694342 11111.173526587858 9953.940473216016 10725.788270130752 12156.416686271672 8748.122180585264 15813.8113165505 8949.304473131102 1.2460939929947694 1.1238480145659753 0.8969650099395773 1.2415683877945412 1.1122585563047025 1.1985052360586532 1.3583644095213685 0.9775197845653976 1.7670436137276382 1.0 13.127559847244989 -6.907099695548371 1.3525611991684117 1.2834279678286673 1.1084023257753672 0.08852114697660651 0.22281726529602575 1.0324575695502496 3.9049617834611374 0.10793145823262153 0.085613016279736 1.2385122441410849e-07 6.907099695548371 -0.17502564205330007 ASSSGPRS(ph)PLDQR ddPTM_PC-9_AZD4547_30min_R2 1 ASSSGPRSPLDQR 13 1 O14646;O14646-2 O14646 CHD1 Chromodomain-helicase-DNA-binding protein 1 1 AS(0.012)S(0.09)S(0.09)GPRS(0.809)PLDQR 117.48 0.0012454 9878000.0 8205.7 6513.7 9716.9 17781.0 11919.0 9319.6 9221.9 12091.0 7728.4 10533.0 True False 10814.941910837031 8619.126142654031 9588.047557090324 13681.865163711513 10264.252586915854 8736.843938729888 10042.631234812505 10222.613773539391 8136.90744615869 10164.242875995682 1.0640184461134896 0.8479850636990715 0.9433115357498859 1.3460781418381098 1.0098393665067134 0.8595666244224839 0.9880353467870804 1.0057427688668834 0.8005424059056248 1.0 13.311215133863676 -6.535549548705204 24.161747546682363 0.9347135961677397 1.0469620910225317 0.15495063720619673 0.13262589067110325 337.0647672929667 642736.8327498416 0.04615750512879777 0.04618881323483673 2.9137376871534903e-07 6.535549548705204 0.11224849485479194 ASSSGPRS(ph)PLDQR ddPTM_PC-9_Lapatinib_30min_R1 2 ASSSGPRSPLDQR 13 1 O14646;O14646-2 O14646 CHD1 Chromodomain-helicase-DNA-binding protein 1 1 ASSS(0.043)GPRS(0.956)PLDQR;AS(0.021)S(0.021)S(0.002)GPRS(0.957)PLDQR 103.66 0.0069626 48032500.0 69207.0 58951.0 69793.0 56071.0 61746.0 65000.0 66851.0 62171.0 70602.0 51723.0 True False 68220.09548899057 58814.502581438646 64054.88894877102 60194.64838737274 58114.22167730671 62220.10152240062 70312.21767554483 65059.69162639403 62650.0592879804 60663.251633434666 1.124570372541503 0.9695243990024254 1.0559092568237316 0.9922753358343941 0.9579806573585803 1.025663805467821 1.1590578444494744 1.0724728707179332 1.0327514203582635 1.0 15.888535210015714 -7.026826225995582 24.9618070514597 1.0750029273922763 1.015106666537615 0.11605383623693422 0.0583024932902743 1207.5373233711425 1123609.9837454355 0.021700061565029564 0.016864674363818905 9.400993967558058e-08 7.026826225995582 -0.059896260854661376 ASSSKESPS(ph)PSVR ddPTM_PC-9_AZD4547_30min_R2 1 ASSSKESPSPSVR 13 1 H0Y517;H7C1U3;Q5T0F9-3;Q5T0F9-2;Q5T0F9 H0Y517 CC2D1B Coiled-coil and C2 domain-containing protein 1B 1 AS(0.032)S(0.018)S(0.002)KES(0.015)PS(0.927)PS(0.005)VR 94.45 0.025586 0.0 8301.3 9327.7 11175.0 14542.0 13615.0 9214.5 11041.0 15651.0 9430.3 12668.0 True False 10940.940722233501 12342.696611884796 11026.812198384705 11189.566571660354 11724.79226200683 8638.315858344406 12023.627610748863 13232.497574201057 9928.76640566098 12224.497175839108 0.8950012883848941 1.0096690632216188 0.9020258289378522 0.9153396177125205 0.9591226611087194 0.7066397688256212 0.983568275880725 1.0824574118561043 0.8122024376826324 1.0 13.577487504289955 -10.780432052314602 5.263962206468893 1.0000096033463866 0.9222618143641719 0.056252249157238254 0.0991092033880486 1.1109721211439087e-05 1.566985598789487e-06 0.09544449873297833 0.02314583226600007 1.6579367095891034e-11 10.780432052314602 -0.07774778898221468 ASST(ph)PSSETQEEFVDDFR ddPTM_PC-9_AZD4547_30min_R2 1 ASSTPSSETQEEFVDDFR 18 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0;F5H367;F5H270 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 AS(0.005)S(0.13)T(0.853)PS(0.008)S(0.003)ET(0.001)QEEFVDDFR 142.55 0.0004577 2050200.0 4617.1 4221.6 7053.4 8176.4 8742.1 6370.4 5007.7 6269.3 6596.3 6856.9 True False 6085.241758354032 5586.14964211251 6959.867307390309 6291.457304120734 7528.4103146301795 5972.0578809481985 5453.375598799659 5300.5237391820765 6944.966951386656 6616.842018077925 0.9196595206185211 0.8442319805808493 1.0518412391251297 0.9508247721393068 1.137764857323441 0.9025540982589418 0.8241659063191247 0.8010654817963728 1.0495893558305092 1.0 12.691927119233203 -6.955491613224075 24.999582570219005 0.8965880655934227 0.9800092015926992 0.08096831999831966 0.1007218513672176 277.1777342783441 155684.9731779859 0.03603691499166921 0.03178155216414085 1.107919960503907e-07 6.955491613224075 0.08342113599927647 ASST(ph)PSSETQEEFVDDFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSTPSSETQEEFVDDFR 18 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0;F5H367;F5H270 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 AS(0.003)S(0.016)T(0.46)PS(0.271)S(0.065)ET(0.185)QEEFVDDFR 121.26 0.00029706 0.0 4613.1 4948.7 4318.4 4586.3 7100.0 5233.8 4575.7 4756.5 5996.7 4342.3 True False 5394.006717121848 5439.974231181065 4421.367033623201 4329.34447998522 5708.805967776458 4959.330314421677 4142.256570800782 4631.646914928336 6084.39039285819 5129.524616372112 1.0515607430570812 1.0605221025391083 0.8619447929953088 0.8440050109452784 1.1129308064056131 0.9668206481732793 0.8075322531019296 0.9029388220782332 1.1861509297447164 1.0 12.324609413538932 -8.249582998632986 24.703352369910824 1.0930754764233863 0.9492840369579351 0.22965896422778154 0.10401999419481459 856.8042342603038 1785205.1525388977 0.07469009669803717 0.027702544082337275 5.6288153402789074e-09 8.249582998632986 -0.14379143946545125 ASSTPS(ph)SETQEEFVDDFR ddPTM_PC-9_AZD4547_30min_R2 1 ASSTPSSETQEEFVDDFR 18 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0;F5H367;F5H270 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 AS(0.009)S(0.037)T(0.206)PS(0.569)S(0.037)ET(0.142)QEEFVDDFR 97.083 0.00079466 2076200.0 3993.0 3235.4 5444.5 6652.7 7491.1 5797.0 3904.8 7343.9 5184.3 5507.3 True False 5262.690940440458 4281.179778304625 5372.302372626893 5119.022798190401 6451.090070798341 5434.512673592981 4252.319635400067 6209.06900103349 5458.331514041786 5314.491103291654 0.9902530342333036 0.8055672114406168 1.0108780442401026 0.9632197511855489 1.2138678841333854 1.02258383125846 0.8001367492677322 1.168328045029139 1.0270656979105752 1.0 12.375715835702062 -5.418792230672917 7.091806836148975 1.0295607835835952 0.8981500058082494 0.17046286791619103 0.11325750821166018 0.42853749559801046 25.45854249311746 0.02995250523240786 0.06274514589594997 3.812481713964561e-06 5.418792230672917 -0.1314107777753457 ASSTPSSET(ph)QEEFVDDFR ddPTM_PC-9_AZD4547_30min_R2 1 ASSTPSSETQEEFVDDFR 18 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0;F5H367;F5H270 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 ASS(0.001)T(0.016)PS(0.117)S(0.124)ET(0.742)QEEFVDDFR 78.705 0.01066 2104100.0 12004.0 11299.0 16079.0 22833.0 21703.0 16317.0 15315.0 18376.0 18660.0 19142.0 True False 15821.02230128908 14951.180786012239 15865.78195416804 17569.204616333427 18689.913071049166 15296.69541056006 16678.005330913747 15536.41143847159 19646.32950485498 18471.84440637134 0.856493913289572 0.8094037854094989 0.8589170418031232 0.9511342901022611 1.0118054624043178 0.8281087190883818 0.9028879284605246 0.8410860927949754 1.0635824486524224 1.0 14.173040305592334 -1.5228787473283962 0.09964437862477071 1.0541051140789994 0.42318160551414596 0.30191561372282516 0.07029599706199538 185.9610170993964 1.3189926193868593 0.9564066880419859 16.036488602517885 0.02999999985852512 1.5228787473283962 -0.6309235085648535 ASSTPSSET(ph)QEEFVDDFR ddPTM_PC-9_Lapatinib_30min_R1 1 ASSTPSSETQEEFVDDFR 18 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0;F5H367;F5H270 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 ASS(0.039)T(0.254)PS(0.11)S(0.145)ET(0.452)QEEFVDDFR 113.28 0.00038859 1716900.0 10364.0 11882.0 17021.0 12034.0 11928.0 13481.0 11706.0 12353.0 14508.0 11339.0 True False 10216.207459475167 11854.487959027898 15621.59908296005 12919.02050424718 11226.418491350287 12904.449055745896 12312.079402102107 12926.96547684363 12873.956263987136 13298.93104173222 0.7681976414056569 0.8913865273703848 1.1746507319978778 0.9714330019237731 0.8441594633524784 0.970337316228768 0.9257946645084962 0.9720304163002759 0.9680444408342666 1.0 13.699022667172917 ASSTS(ph)TPEPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSTSTPEPTR 11 0 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 1 AS(0.006)S(0.087)T(0.087)S(0.409)T(0.409)PEPT(0.003)R 69.26100000000001 0.035157 1210900.0 4584.5 3821.4 7615.8 6429.5 9061.0 8199.2 6534.9 6714.7 6498.8 4794.6 True False 5360.565301997601 4200.763337247224 7797.389555082339 6069.275959720246 7285.562094932746 7769.219518133329 5915.866963421125 6538.4462398127325 6593.83265547831 5663.823025967286 0.9464570622035114 0.7416833679279383 1.3767007760188048 1.071586441153626 1.2863329347562893 1.3717270971415065 1.0445006731845745 1.1544227653010177 1.1642017459315288 1.0 12.467560471772929 -5.252877249002959 24.998513407263207 1.1906066874827839 0.8440701958993418 0.5179163998400198 0.130925746000484 463.10185973138823 1352092.9715192309 0.032255662161148585 0.08251067344147006 5.586280656401632e-06 5.252877249002959 -0.346536491583442 ASSTST(ph)PEPTR ddPTM_PC-9_AZD4547_30min_R2 4 ASSTSTPEPTR 11 0 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 1 ASST(0.043)S(0.023)T(0.934)PEPTR;ASS(0.003)T(0.004)S(0.028)T(0.964)PEPTR;ASS(0.001)T(0.004)S(0.229)T(0.766)PEPTR;ASS(0.002)T(0.008)S(0.037)T(0.952)PEPTR 137.01 0.00021298 376540330.0 77976.35 83177.8 142749.0 171307.8 155478.4 156071.5 176243.6 214183.9 149001.7 187057.6 True False 102771.20729116305 110063.39721946788 140856.05498946033 131815.4333891266 133892.907912538 146312.32443275256 191928.93897090663 181086.69971138772 156877.62566900047 180508.77035990192 0.5693419055830684 0.6097398868765287 0.780328040064861 0.7302439273521748 0.7417529222850486 0.8105552109242792 1.0632665581192258 1.003201669095266 0.8690858918168618 1.0 17.4617094093185 -6.327933924212702 0.5655692633481157 1.003731770291954 0.5668159339609913 0.7852254842117357 0.07333174625086422 0.5073628579477701 0.3371228559344563 0.0606697993550459 0.11515958155912787 4.6996560614095413e-07 6.327933924212702 -0.43691583633096265 ASSTST(ph)PEPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ASSTSTPEPTR 11 0 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 1 AS(0.001)S(0.007)T(0.037)S(0.026)T(0.929)PEPTR;ASST(0.173)S(0.115)T(0.711)PEPTR;AS(0.004)S(0.004)T(0.004)S(0.03)T(0.954)PEPT(0.003)R;AS(0.001)S(0.004)T(0.011)S(0.033)T(0.951)PEPT(0.001)R 132.32 0.00027907 245845900.0 275059.2 331633.0 481512.0 549442.0 568368.0 456281.0 481847.0 499664.0 429024.0 349540.0 True False 321621.2898931664 364555.3325538573 492993.0722244281 518658.5460549993 457000.3704638263 432352.8211232063 436202.96388981945 486548.34943776904 435297.66436633345 412908.83504288236 0.7789159799880878 0.8828954520093925 1.1939513771199124 1.2561091021487452 1.1067827367180574 1.0470902640731932 1.0564147019148136 1.1783432761549868 1.0542222094160953 1.0 18.655463762740645 -5.113244072176323 4.267737175498535 1.1180117302842265 0.7998857375772621 0.695481449227285 0.07537662892719522 0.119452983165903 3.5333826395281327 0.020433471551729632 0.06249573390272836 7.70470345380855e-06 5.113244072176323 -0.3181259927069644 ASSTST(ph)PEPTR ddPTM_PC-9_Lapatinib_30min_R1 4 ASSTSTPEPTR 11 0 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 1 AS(0.002)S(0.008)T(0.067)S(0.018)T(0.906)PEPTR;AS(0.042)S(0.071)T(0.123)S(0.021)T(0.743)PEPTR;ASS(0.001)T(0.003)S(0.024)T(0.972)PEPTR;AS(0.001)S(0.002)T(0.009)S(0.048)T(0.941)PEPTR 126.19 0.0010343 334417600.0 144802.2 182424.0 215682.0 185066.5 164289.7 147548.8 145353.6 144462.6 176715.2 117679.7 True False 142737.29407452868 182001.6084360975 197949.45851659638 198676.90777374653 154626.50285197765 141238.48177705202 152879.29818737318 151174.8597826497 156811.67328244675 138020.47934665595 1.034174745300122 1.3186565450115368 1.4342035287344654 1.4394741180020412 1.1203156486916233 1.023315398161411 1.1076566239376506 1.0953074536348686 1.1361478675102579 1.0 17.074522823032936 -6.403792656498939 6.213980904406103 1.0798331730540613 1.3156521235253253 0.5026229715592349 0.11071634273844229 0.208311954455599 9.824081572969286 0.03623005647090788 0.041043058178870814 3.9464567123133843e-07 6.403792656498939 0.235818950471264 ASSTSTPEPTR ddPTM_PC-9_Lapatinib_30min_R1 1 ASSTSTPEPTR 11 0 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 0 96.665 0.026311 1359800.0 2942.1 3468.6 3433.4 1936.4 2769.8 2725.6 1140.6 3195.4 1165.8 1733.4 False True 2900.145114484937 3460.5686698101504 3151.1191053072685 2078.809315641036 2606.8858096363183 2609.0324416839267 1199.654687001338 3343.8699493812137 1034.4953275817627 2033.0158803896843 1.4265235911138299 1.7021847705128774 1.5499726960830569 1.0225248782820988 1.2822751827873748 1.2833310683160195 0.59008623521986 1.644782995369553 0.5088476374239993 1.0 10.989405769136402 -5.935439366404493 0.7174638675852681 0.9894057535684693 1.6580493305646045 0.33308222016743794 0.3224167480915223 1.1033965176222418 1.0770935978664316 0.16787748186958798 0.4734063058741157 1.160274195377275e-06 5.935439366404493 0.6686435769961352 ASSVGVLS(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 1 ASSVGVLSPQK 11 0 Q9UGU5 Q9UGU5 HMGXB4 HMG domain-containing protein 4 1 ASSVGVLS(1)PQK 73.273 0.02515 2388000.0 45586.0 42986.0 42538.0 41027.0 37016.0 34990.0 32274.0 27971.0 38698.0 45165.0 True False 44935.935280551465 42886.46855805195 39040.689841428495 44044.262442059924 34838.79165625605 33493.55926567381 33944.98980210519 29270.634773155794 34339.42373199438 52971.710071420406 0.8483006348098917 0.8096107998067122 0.7370101850363322 0.8314676340007934 0.6576867465536566 0.6322914480298124 0.6408135541846398 0.5525710748943341 0.6482596783395402 1.0 15.69293446307119 -6.268227602863431 24.154963976350967 0.6610271698452678 0.8018420533758943 0.17522680537919344 0.11635007785627122 458.8831905988904 1632869.7558888567 0.03372926654980081 0.03914407482758226 5.392279525835525e-07 6.268227602863431 0.14081488353062654 ASSVGVLS(ph)PQKK ddPTM_PC-9_AZD4547_30min_R2 1 ASSVGVLSPQKK 12 1 Q9UGU5 Q9UGU5 HMGXB4 HMG domain-containing protein 4 1 ASSVGVLS(1)PQKK 99.834 0.004733 15412000.0 29183.0 28641.0 36171.0 39800.0 37027.0 39952.0 36921.0 39573.0 34574.0 40590.0 True False 38462.58695589128 37898.643144718684 35691.34890628845 30624.724903870305 31886.440182543287 37453.79512426889 40206.89747454568 33457.90214707421 36401.511055780065 39168.95645463447 0.981966088385293 0.9675683647230412 0.9112152106382055 0.7818621601354097 0.8140742840436456 0.9562112068941105 1.0264990725783913 0.8541943716531021 0.9293459502282205 1.0 15.257423071846821 ASSVGVLS(ph)PQKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSVGVLSPQKK 12 1 Q9UGU5 Q9UGU5 HMGXB4 HMG domain-containing protein 4 1 AS(0.001)S(0.007)VGVLS(0.992)PQKK 62.104 0.024324000000000002 66836000.0 128180.0 130520.0 114150.0 155150.0 154740.0 151140.0 163960.0 141290.0 126520.0 132490.0 True False 149878.34232960024 143477.16302337014 116871.76891628577 146457.44850308643 124419.80781038431 143213.95233323643 148428.5218323964 137581.28720912922 128370.11564767602 156509.38820973728 0.9576316414242779 0.9167319907422886 0.7467396700807917 0.9357742061250645 0.7949670574627132 0.9150502341835001 0.9483681683905647 0.8790609226889148 0.8202071269721405 1.0 17.255889674197867 ASSVS(ph)TKESPAR ddPTM_PC-9_AZD4547_30min_R2 1 ASSVSTKESPAR 12 1 E7ETY2;Q13428-6;Q13428-7;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4 E7ETY2;Q13428 TCOF1 Treacle protein 1 AS(0.025)S(0.388)VS(0.499)T(0.086)KES(0.002)PAR 65.895 0.01913 170810000.0 90140.0 101590.0 124180.0 150250.0 152630.0 129870.0 110530.0 150150.0 112050.0 137750.0 True False 118802.64497152567 134426.9807992729 122533.29206222945 115612.18383935971 131439.9590855751 121749.20836976348 120366.95587501801 126947.7676037497 117972.73424539117 132927.41442783686 0.8937407342412487 1.011281091849192 0.9218060291750417 0.8697392056935165 0.9888100182444363 0.9159074438768854 0.9055088929030691 0.955015698982595 0.8874973966294648 1.0 17.02027914549501 ASSVS(ph)TKESPAR ddPTM_PC-9_Lapatinib_30min_R1 2 ASSVSTKESPAR 12 1 E7ETY2;Q13428-6;Q13428-7;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4 E7ETY2;Q13428 TCOF1 Treacle protein 1 AS(0.007)S(0.009)VS(0.748)T(0.167)KES(0.068)PAR;ASSVS(0.796)T(0.18)KES(0.024)PAR 90.759 0.011918999999999999 149667600.0 478155.5 394952.2 498682.7 389713.1 414408.0 385282.3 402989.4 378289.3 433660.7 374407.0 True False 471336.9148870206 394037.7124466899 457682.93337688985 418373.90141879144 390033.33619747584 368804.67416590836 423854.21928972146 395866.0018909857 384817.2653163807 439122.7510840307 1.0733602705017335 0.8973293036490534 1.0422665012164387 0.9527493175563824 0.8882102674813105 0.8398669238964886 0.9652294677134879 0.9014928079079023 0.8763318784244497 1.0 18.74426475730894 -6.016204708548657 5.640542166924836 0.9068746797822311 0.9945848295973287 0.31826774504658273 0.059867001024469624 0.20126134562931922 21.859493489248354 0.01668018192541727 0.02306601097513143 9.633748213358884e-07 6.016204708548657 0.08771014981509762 ASSVSTKES(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 2 ASSVSTKESPAR 12 1 E7ETY2;Q13428-6;Q13428-7;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4 E7ETY2;Q13428 TCOF1 Treacle protein 1 ASSVST(0.002)KES(0.998)PAR;ASSVS(0.039)T(0.026)KES(0.935)PAR 137.73 0.00032469 115708000.0 29748.0 21826.1 41148.0 57105.0 46481.0 40029.0 33273.0 44894.0 34896.3 41412.0 True False 39207.245203161256 28880.959992351687 40602.350634374394 43940.3245134551 40027.915470461965 37525.9803020965 36234.23254165808 37956.66386149017 36740.84717579159 39962.178484831784 0.9811088056183656 0.7227073469809427 1.0160194507360403 1.0995477769094415 1.0016449800316851 0.9390374029869273 0.9067131451657797 0.949814682297592 0.9193904979363701 1.0 15.286347611418437 -5.293284267484607 24.97572359159431 0.9783307842238059 0.8519079447326879 0.29601527014940043 0.07840469311000581 715.3003837383615 561003.9203980828 0.021039410669409325 0.04380243490970151 5.089975975826167e-06 5.293284267484607 -0.126422839491118 ASSVSTKES(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASSVSTKESPAR 12 1 E7ETY2;Q13428-6;Q13428-7;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4 E7ETY2;Q13428 TCOF1 Treacle protein 1 ASSVS(0.045)T(0.297)KES(0.658)PAR 104.9 0.008951299999999999 43393000.0 15895.0 14669.0 17746.0 19686.0 20418.0 20004.0 20619.0 23149.0 21443.0 14245.0 True False 18585.709559439812 16125.241375956324 18169.131942079788 18583.057242873132 16417.239471839406 18954.955024970623 18665.81905136729 22541.36327839294 21756.56330882955 16827.505736642037 1.1044839235424697 0.9582668773568428 1.0797281680621478 1.1043263056157138 0.9756193061988223 1.1264268942542117 1.1092445513610676 1.339554633418364 1.292916707284458 1.0 14.03853372805001 -7.431456525674042 2.535675539671796 1.234224947902719 1.050695199907543 0.29669287604998495 0.09943225684476313 0.290519723818627 3.6522721696460585 0.04867862504263042 0.02852194269611233 3.702912709360095e-08 7.431456525674042 -0.18352974799517607 ASSVSTKES(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 3 ASSVSTKESPAR 12 1 E7ETY2;Q13428-6;Q13428-7;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4 E7ETY2;Q13428 TCOF1 Treacle protein 1 ASSVS(0.006)T(0.006)KES(0.988)PAR;ASSVST(0.005)KES(0.995)PAR;ASS(0.001)VS(0.097)T(0.036)KES(0.866)PAR 181.75 0.0013731 233042000.0 78926.0 69788.0 89996.0 83007.0 83674.0 75945.0 73577.0 71357.0 84232.0 61051.9 True False 77800.50076674428 69626.41017376192 82596.87627460623 89111.61168323454 78752.45982941336 72697.0093864417 77386.45704497414 74672.5067215359 74744.9051577175 71604.63956845667 1.0865287673484363 0.9723728880332749 1.1535129116269145 1.2444949408346726 1.0998234235104711 1.0152555731663266 1.0807464084920062 1.0428445303484315 1.0438556161749635 1.0 16.127765448401412 -6.64721442601949 6.425876535166502 1.042310363223808 1.1145979727724051 0.24292811617450805 0.06591792427461084 0.3820335920315743 20.08592906384646 0.024171317345604165 0.024108992233944235 2.2531264919741167e-07 6.64721442601949 0.07228760954859714 AST(ph)FCGTPDYIAPEILQGLK ddPTM_PC-9_AZD4547_30min_R2 1 ASTFCGTPDYIAPEILQGLK 20 0 Q05655;Q05655-2 Q05655 PRKCD Protein kinase C delta type;Protein kinase C delta type regulatory subunit;Protein kinase C delta type catalytic subunit 1 AS(0.421)T(0.555)FCGT(0.024)PDYIAPEILQGLK 121.14 2.1986e-05 2751500.0 21099.0 27356.0 34141.0 30605.0 28155.0 31484.0 30286.0 28504.0 25474.0 27228.0 True False 27808.04311353699 36198.29202426328 33688.26803266687 23549.490092536456 24246.16424067591 29515.300502915554 32981.39532824381 24099.36175675848 26820.503633798264 26274.756007558208 1.0583559027356035 1.377683279488893 1.282153410786235 0.8962781647054001 0.9227931263643798 1.1233330004824849 1.2552502987565848 0.9172059200026842 1.0207707971135134 1.0 14.68138974665526 -5.744860313043578 24.999446716782625 1.0260615064106864 1.2532261993077491 0.39191862629927277 0.12504195105358556 255.32812422050844 385004.34145174944 0.03544443714279986 0.06117015297549982 1.799449599014335e-06 5.744860313043578 0.22716469289706276 AST(ph)GPPLIK ddPTM_PC-9_AZD4547_30min_R2 1 ASTGPPLIK 9 0 A0A087WZ32;A0A087X038;A8K727;Q9HB19;E5RHB5 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 AS(0.193)T(0.807)GPPLIK 106.2 0.0021429 0.0 12738.0 12080.0 16592.0 19805.0 19748.0 21497.0 18528.0 18366.0 18256.0 18550.0 True False 16788.419033140643 15984.623762724832 16371.97923897979 15239.263234199792 17006.331075292754 20152.78919169023 20176.95610650799 15527.956708694444 19220.974889637317 17900.570146180566 0.9378706318313988 0.8929672983704076 0.9146065798620984 0.8513283716525301 0.9500441011886643 1.1258182855136722 1.1271683494848423 0.8674559850266912 1.0737632786371603 1.0 14.127717918657293 -6.533077979092047 23.13405211525812 1.0362836548879066 0.8999540512660589 0.4601027564573099 0.07180955425493529 81.8360373467915 185618.42479695255 0.024274396301562366 0.02431045533127767 2.9303670403672967e-07 6.533077979092047 -0.13632960362184776 AST(ph)PDWVSEGPQPGLR ddPTM_PC-9_AZD4547_30min_R2 2 ASTPDWVSEGPQPGLR 16 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 AS(0.028)T(0.972)PDWVSEGPQPGLR;AS(0.002)T(0.998)PDWVSEGPQPGLR 186.29 1.4444000000000001e-07 135734300.0 26558.7 30003.8 38138.7 43611.0 40588.4 49160.9 44882.3 55241.0 53303.8 51716.1 True False 35003.81414472228 39701.94159371215 37632.95591861612 33557.15773323339 34953.40126678208 46086.861151498575 48876.737751463945 46704.772761896405 56121.33004613553 49905.53508015576 0.701401439509684 0.795541847811969 0.7540838077013293 0.6724135444963284 0.7003912734457548 0.9234819560090114 0.9793851057394855 0.9358635808008381 1.1245512137280218 1.0 15.606912214948428 -6.897619906125287 3.3591440841957954 1.0008421916470123 0.727052714263591 0.8569465621793201 0.05543260410861113 0.0931572423884878 2.0744076223376298 0.02151830722526509 0.018663636357957505 1.2658437273304234e-07 6.897619906125287 -0.2737894773834213 AST(ph)PDWVSEGPQPGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ASTPDWVSEGPQPGLR 16 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 AS(0.004)T(0.996)PDWVSEGPQPGLR;AS(0.002)T(0.998)PDWVS(0.001)EGPQPGLR;AST(0.999)PDWVSEGPQPGLR;AS(0.143)T(0.857)PDWVSEGPQPGLR 182.37 2.9973e-06 173856200.0 40028.5 51222.5 61691.0 63234.0 83349.0 67866.0 73369.0 77646.0 64593.5 58708.0 True False 46804.53445108756 56307.53128229073 63161.947404420316 59691.20398739405 67017.36177580283 64306.987488735045 66418.9571744396 75607.8747727375 65538.0577386039 69351.29566772765 0.6748905554026708 0.8119175098338244 0.9107536751301458 0.8607078413269086 0.966346210702291 0.9272643988778431 0.957717610535536 1.0902157493204747 0.9450156209424904 1.0 16.08163521575289 -3.6701235437479056 0.4266513855920346 1.0050669396257244 1.8715356109375348e-15 0.8157562667560003 0.045966305480889424 5.413085871505708 0.36923177700479526 0.03246477881527835 3.3642147124890487 0.00021373539899403188 3.6701235437479056 -1.0050669396257226 AST(ph)PDWVSEGPQPGLR ddPTM_PC-9_Lapatinib_30min_R1 5 ASTPDWVSEGPQPGLR 16 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 AS(0.004)T(0.996)PDWVSEGPQPGLR;AS(0.041)T(0.959)PDWVSEGPQPGLR;AS(0.005)T(0.995)PDWVSEGPQPGLR;AST(1)PDWVSEGPQPGLR;AS(0.046)T(0.934)PDWVS(0.02)EGPQPGLR 270.07 4.903699999999999e-69 277531500.0 109038.2 145041.7 136508.0 139674.0 180780.0 171437.0 148670.3 135491.0 160740.0 149871.0 True False 107483.29527284332 144705.86485498532 125284.83917611824 149946.09189880508 170146.87582715496 164105.03914916608 156367.7206846353 141786.4064942134 142635.7685327608 175776.00265944563 0.6114787778004321 0.82324016171504 0.7127528063022877 0.8530521210526998 0.9679755669310746 0.9336032033172852 0.8895851442678863 0.8066311916815812 0.8114632621900508 1.0 17.423378598346098 -3.92486955058721 0.6611739670272563 0.8913026875796294 3.1071632406146723e-10 0.5635458141627125 0.07356096394720496 7.359853594023047 1.0540978256780922 0.0331938589661367 6.404579141973818 0.0001188859272509254 3.92486955058721 -0.891302687268913 AST(ph)PDWVSEGPQPGLRR ddPTM_PC-9_AZD4547_30min_R2 4 ASTPDWVSEGPQPGLRR 17 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 AS(0.398)T(0.602)PDWVSEGPQPGLRR;AS(0.199)T(0.801)PDWVSEGPQPGLRR;AS(0.003)T(0.996)PDWVS(0.001)EGPQPGLRR;AS(0.164)T(0.836)PDWVSEGPQPGLRR 127.53 2.8989e-05 56108100.0 80984.0 64544.0 106485.0 243753.0 200842.0 126054.0 94087.0 137384.0 107410.0 146609.0 True False 106735.2274281566 85406.58577328738 105072.93932393704 187559.51179630918 172958.5550852722 118171.82345300811 102460.56072932933 116154.45957025353 113087.4733181391 141476.26353430675 0.7544391176423333 0.6036813783435625 0.7426895275507314 1.3257313072226256 1.2225270215970276 0.8352766782277402 0.7242243905069173 0.8210172976620004 0.7993388466236697 1.0 17.110200496724346 -5.543495410865585 24.99992004014877 0.9559928286969255 0.6775913153196411 0.30456217320615175 0.1822360488830501 306.8602481119672 372099.4057885711 0.05620379742442059 0.09736002598611121 2.8609125913660517e-06 5.543495410865585 -0.27840151337728436 AST(ph)PDWVSEGPQPGLRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ASTPDWVSEGPQPGLRR 17 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 AS(0.189)T(0.811)PDWVSEGPQPGLRR;AS(0.142)T(0.858)PDWVSEGPQPGLRR;AS(0.158)T(0.842)PDWVSEGPQPGLRR;AS(0.223)T(0.73)PDWVS(0.046)EGPQPGLRR 141.6 1.8494e-05 49142800.0 78280.0 37248.3 97729.0 127097.0 136276.0 208840.0 134670.0 193972.0 163989.0 129239.0 True False 91531.25789952511 40946.065058561195 100059.2299992965 119976.16714403353 109573.69606545124 197888.0627581917 121913.08267363292 188880.44053032203 166387.02888829226 152669.00764463923 0.5995405309280473 0.2682015537421289 0.6553997536435152 0.785858040181257 0.7177206281480586 1.2961901423948914 0.7985450652656662 1.2371891547888392 1.0898546565232405 1.0 17.220047694034065 -6.079001072852237 0.986669112544488 1.0869288812462308 0.4235078921041916 0.6659909184645127 0.1726193222210244 0.3212664214181837 0.6445069754631119 0.07201731513466565 0.14048550228857024 8.336791251515628e-07 6.079001072852237 -0.6634209891420392 AST(ph)PDWVSEGPQPGLRR ddPTM_PC-9_Lapatinib_30min_R1 4 ASTPDWVSEGPQPGLRR 17 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 AS(0.217)T(0.783)PDWVSEGPQPGLRR;AS(0.186)T(0.814)PDWVSEGPQPGLRR;AS(0.006)T(0.993)PDWVS(0.001)EGPQPGLRR;AS(0.006)T(0.994)PDWVSEGPQPGLRR 134.06 3.4381e-05 36179100.0 301095.0 127993.0 131708.0 126020.0 110536.0 122752.0 75503.0 66923.0 147159.0 85570.0 True False 296801.3300859401 127696.6400723666 120879.47664758269 135287.93119039625 104034.48980213741 117502.18310888804 79412.17590098362 70032.486894423 130584.4037670308 100360.66048514187 2.95734731767614 1.2723774380826416 1.2044507884190199 1.348017545285339 1.0366062688232252 1.170799220938606 0.7912679681172524 0.6978081506826186 1.301151299082607 1.0 16.6148343448711 -2.9386100688720598 1.268099809785433 1.0344088102893862 199.9999999987325 0.8845602392335306 0.20248538343499975 49.00174045448326 1.0033610762449543 0.06206282196500727 27506.04434193985 0.0011518340986046557 2.9386100688720598 198.9655911884431 up AST(ph)PVLK ddPTM_PC-9_AZD4547_30min_R2 1 ASTPVLK 7 0 A0A669KBK8;Q04724;F6T2C8;A0A669KAE5 A0A669KBK8 TLE1 Transducin-like enhancer protein 1 1 AS(0.022)T(0.978)PVLK 90.709 0.038501 24584000.0 226260.0 200430.0 249870.0 345980.0 331830.0 271980.0 231360.0 323080.0 262050.0 274080.0 True False 298205.97349963925 265215.0778777263 246556.5605378426 266219.65633771475 285761.13230273477 254973.04760459118 251950.5917962911 273155.4096398237 275901.4280143218 264484.542623459 1.1274986830674212 1.0027621094488963 0.9322153880609193 1.006560359622702 1.0804454939718984 0.9640376147334662 0.9526098928018933 1.0327840218197901 1.0431665505954226 1.0 18.012823883233125 AST(ph)PVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASTPVLK 7 0 A0A669KBK8;Q04724;F6T2C8;A0A669KAE5 A0A669KBK8 TLE1 Transducin-like enhancer protein 1 1 AS(0.019)T(0.981)PVLK;AS(0.026)T(0.974)PVLK 110.41 0.023153999999999997 23272500.0 230932.0 211718.0 199390.0 258942.0 254074.0 219490.0 216929.0 197261.0 191642.0 172914.0 True False 270024.2264850933 232735.963844483 204144.21379078538 244434.3192412909 204290.0235854697 207979.5580099381 196379.91469004567 192083.1077653064 194444.40169895603 204261.93941352898 1.3219507621457973 1.1393995597648188 0.9994236536523563 1.196670901799443 1.0001374909688088 1.0182002511436201 0.9614121713222055 0.9403764025584498 0.951936529425106 1.0 17.640060882938826 -1.5228787476433299 0.3929231094499598 0.9608400867863378 6.181068546993068 0.7313994038716591 0.06163059286994443 37.863522707079596 0.5077369509069466 0.04649992911998756 152.13799430827675 0.029999999836770274 1.5228787476433299 5.22022846020673 AST(ph)PYIEK ddPTM_PC-9_AZD4547_30min_R2 1 ASTPYIEK 8 0 C9J618;C9J5A2;C9J347;C9J7P5;C9IZN7;Q969Z0-2;Q969Z0 C9J618 TBRG4 Protein TBRG4 1 AS(0.001)T(0.999)PYIEK 150.27 0.001442 10159000.0 81487.0 96450.0 123770.0 169130.0 148070.0 134870.0 131520.0 167460.0 132360.0 145130.0 True False 107398.17096510682 127625.57631745098 122128.72893011867 130139.69153245179 127513.03637424519 126436.55757934904 143225.02521199995 141582.90484797812 139356.27938170455 140049.0428741339 0.7668611563566959 0.911292028122975 0.8720425818252772 0.9292437053597864 0.9104884528832147 0.902802011242456 1.0226776440073237 1.0109523202898483 0.9950534221568942 1.0 17.09557259818869 -2.0905434627159933 0.23571016455406957 1.0257881162280404 2.1320226687850205e-11 0.7601108648891582 0.03654492143201168 19.52597825960318 0.32737432331934785 0.05388075377766759 7.374486125661326 0.008118140012835864 2.0905434627159933 -1.0257881162067202 AST(ph)PYIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASTPYIEK 8 0 C9J618;C9J5A2;C9J347;C9J7P5;C9IZN7;Q969Z0-2;Q969Z0 C9J618 TBRG4 Protein TBRG4 1 AS(0.117)T(0.883)PYIEK;AS(0.005)T(0.995)PYIEK;AS(0.027)T(0.973)PYIEK 135.55 0.0085895 23966500.0 354790.0 364140.0 410830.0 427300.0 516410.0 396150.0 412250.0 390740.0 372850.0 364700.0 True False 414848.9395780839 400289.41268257843 420625.7452814516 403359.7663252921 415223.16758020344 375375.1966177822 373198.69556846406 380483.48902325094 378302.2258871013 430817.22303638887 0.9629348999890003 0.9291397634044173 0.9763438479011866 0.9362665760723834 0.9638035467888705 0.8713096332875164 0.866257604415555 0.8831668482091151 0.8781037657242132 1.0 18.716716400949636 -6.757017063115681 24.999583101294743 0.8903711230604766 0.9526231222914567 0.3158836249068503 0.038443073028641264 112.46276557808136 635758.1839144338 0.012037839579545495 0.011648139270529965 1.749777939766043e-07 6.757017063115681 0.062251999230980126 AST(ph)PYIEK ddPTM_PC-9_Lapatinib_30min_R1 1 ASTPYIEK 8 0 C9J618;C9J5A2;C9J347;C9J7P5;C9IZN7;Q969Z0-2;Q969Z0 C9J618 TBRG4 Protein TBRG4 1 AS(0.003)T(0.997)PYIEK 106.2 0.009364399999999998 8484200.0 164870.0 135800.0 119670.0 111990.0 119250.0 109010.0 74970.0 79574.0 152870.0 71666.0 True False 162518.92356654466 135485.56344352724 109831.1945395588 120226.11818768838 112235.9494545205 104347.89641472154 78851.57976897282 83271.29853916922 135652.17080753474 84053.37261105754 1.9335205538815545 1.6118991925578439 1.306683969098821 1.43035448136048 1.3352938254348574 1.2414480605980371 0.9381132168704864 0.9906955063480054 1.6138813541158155 1.0 16.35901808778698 -1.5228787545821307 0.44245677541187894 1.1404115077393766 18.37827643602447 0.6125810016473909 0.18872477324918693 57.692156282590716 0.706566489635446 0.12200676329334526 894.0521785374679 0.0299999993574549 1.5228787545821307 17.237864928285095 ASTAPGAEAS(ph)PSPCITER ddPTM_PC-9_AZD4547_30min_R2 2 ASTAPGAEASPSPCITER 18 0 Q66PJ3 Q66PJ3 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 ASTAPGAEAS(0.807)PS(0.19)PCIT(0.003)ER;ASTAPGAEAS(0.939)PS(0.049)PCIT(0.012)ER 113.14 0.0001621 21264500.0 41784.0 51214.0 51905.0 82885.0 72819.0 58814.0 48589.0 65525.0 58358.0 52746.0 True False 55070.44283880894 67767.9239556448 51216.70578587551 63777.1438104847 62709.33879743492 55136.35128250776 52913.32687063455 55399.6168647067 61442.68473978171 50899.378594632886 1.0819472527826868 1.3314096522740384 1.006234402069421 1.253004370022107 1.2320256264198741 1.083242129960338 1.0395672468232062 1.0884144049363373 1.207140174128974 1.0 15.635360422806924 -6.77914887302917 24.7474581138556 1.0864420561714065 1.1835840142945242 0.19870318536811793 0.09749500483026313 362.9003118408923 507117.74456859607 0.03301976520713212 0.029183902693106674 1.662842542180804e-07 6.77914887302917 0.09714195812311766 ASTAPGAEAS(ph)PSPCITER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASTAPGAEASPSPCITER 18 0 Q66PJ3 Q66PJ3 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 ASTAPGAEAS(0.978)PS(0.018)PCIT(0.004)ER 121.03 0.00045768 0.0 26713.0 35768.0 34772.0 32823.0 37731.0 34281.0 30636.0 33403.0 32856.0 26954.0 True False 31234.983294200432 39318.81065752305 35601.09635354436 30984.033723601784 30337.881404249805 32483.244011748546 27733.93629456756 32526.206643403995 33336.45684255485 31840.546832253407 0.9809813712922932 1.2348660613358062 1.118105682703968 0.9730999246600877 0.9528065445634416 1.0201848662612825 0.8710257534419608 1.0215341719714448 1.046981291438944 1.0 14.95857749261084 -5.754366901325888 11.031726355915735 0.9800838949510831 1.1237632427723208 0.38559182661590297 0.07324394680532831 0.19368926594615343 272.08764486133157 0.01957566366339981 0.03216549700297034 1.7604881197283136e-06 5.754366901325888 0.1436793478212377 ASTAPGAEAS(ph)PSPCITER ddPTM_PC-9_Lapatinib_30min_R1 2 ASTAPGAEASPSPCITER 18 0 Q66PJ3 Q66PJ3 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 ASTAPGAEAS(0.999)PS(0.001)PCITER;ASTAPGAEAS(0.993)PS(0.007)PCITER 232.73 2.7333e-37 22450000.0 43066.0 41877.0 51121.0 37386.0 53055.0 54020.0 47738.0 46462.0 46907.0 34381.0 True False 42451.87094266287 41780.036379415236 46918.028712766616 40135.491156039956 49934.40921014331 51709.690526770464 50209.64005617208 48620.79413787009 41623.83970739209 40323.71004019713 1.052776912152782 1.0361158816429923 1.1635345226417872 0.9953323024104292 1.2383386637877727 1.2823644073232123 1.245164197592931 1.205761922437244 1.0322423126715996 1.0 15.299340761699684 -6.2675666624691875 24.998496582229045 1.187245252245554 1.0673520895238944 0.21141370307439677 0.0949043796172537 688.860987610558 2810455.5185656273 0.02915513259003927 0.0338752271151549 5.400492130040341e-07 6.2675666624691875 -0.11989316272165973 ASTAS(ph)PCNNNINAATAVALQEPR ddPTM_PC-9_AZD4547_30min_R2 4 ASTASPCNNNINAATAVALQEPR 23 0 Q71RC2-5;Q71RC2-3;Q71RC2;Q71RC2-4;Q71RC2-6 Q71RC2-5 LARP4 La-related protein 4 1 AS(0.139)T(0.139)AS(0.723)PCNNNINAATAVALQEPR;AS(0.155)T(0.155)AS(0.689)PCNNNINAATAVALQEPR;AS(0.064)T(0.231)AS(0.705)PCNNNINAATAVALQEPR;AS(0.213)T(0.182)AS(0.605)PCNNNINAATAVALQEPR 99.774 3.4569999999999997e-06 54120000.0 45977.1 39263.7 57803.6 82735.8 62723.4 68996.0 54216.9 70078.6 40852.4 60716.2 True False 60596.861416910884 51954.923181498256 57037.08649579872 63662.33956536764 54015.33859469401 64681.66921290684 59042.09906794763 59249.56261602491 43011.77446217245 58590.54431857296 1.0342430185906624 0.8867458697602295 0.973486202580272 1.0865633747865173 0.9219122167733705 1.1039608859275098 1.0077069560391767 1.0112478609836544 0.7341077807419839 1.0 15.838380232500228 -8.206987779778913 24.998863735364846 0.8670531872417312 1.0019325403083503 0.28456134644701314 0.08635161626813032 323.8221756038223 148667.79270963947 0.05520054379603736 0.020863819053459593 6.208865045501469e-09 8.206987779778913 0.13487935306661913 ASTAS(ph)PCNNNINAATAVALQEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ASTASPCNNNINAATAVALQEPR 23 0 Q71RC2-5;Q71RC2-3;Q71RC2;Q71RC2-4;Q71RC2-6 Q71RC2-5 LARP4 La-related protein 4 1 AS(0.07)T(0.07)AS(0.859)PCNNNINAATAVALQEPR;AS(0.023)T(0.077)AS(0.9)PCNNNINAATAVALQEPR;AS(0.027)T(0.046)AS(0.928)PCNNNINAATAVALQEPR;AS(0.165)T(0.147)AS(0.688)PCNNNINAATAVALQEPR 108.31 8.973100000000001e-07 42806000.0 54812.4 67435.9 68136.0 72981.0 77330.0 74801.9 74724.2 67326.6 62034.0 55217.5 True False 64091.05672575268 74130.49048366299 69760.62064721884 68892.11117759434 62177.74161804985 70879.15668278096 67645.78281964101 65559.34808842918 62941.12989320204 65227.99564851047 0.9825697706720234 1.1364827287216483 1.0694889510806527 1.056173970894774 0.9532370418539715 1.0866370486795656 1.0370667095791062 1.0050799114187756 0.9649404257700712 1.0 15.993203677051472 -7.22255679685233 0.5424334653483579 0.9847238836301948 1.065615908507282 0.185814413705921 0.05001969822820535 1.463871243679117 0.9088071290929282 0.04735598622293466 0.040177773837424664 5.990225935620056e-08 7.22255679685233 0.08089202487708724 ASTAS(ph)PCNNNINAATAVALQEPR ddPTM_PC-9_Lapatinib_30min_R1 3 ASTASPCNNNINAATAVALQEPR 23 0 Q71RC2-5;Q71RC2-3;Q71RC2;Q71RC2-4;Q71RC2-6 Q71RC2-5 LARP4 La-related protein 4 1 AS(0.067)T(0.233)AS(0.699)PCNNNINAATAVALQEPR;AS(0.086)T(0.071)AS(0.844)PCNNNINAATAVALQEPR;AS(0.061)T(0.223)AS(0.716)PCNNNINAATAVALQEPR 105.61 1.3361000000000002e-06 35243200.0 79125.0 69318.0 83013.0 85163.0 65632.0 75069.0 57212.0 54093.0 79819.0 52834.0 True False 77996.66299025223 69157.49842988518 76187.99157944674 91426.1711154398 61771.6547974766 71858.47386438602 60174.15741953404 56606.35825620521 70828.9436886676 61966.286503120224 1.2586951291058053 1.1160503934087265 1.2295071381372902 1.4754179453828684 0.9968590710105918 1.1596382148988014 0.9710789659229306 0.9135025100036434 1.143023855158742 1.0 15.919195893057307 -6.30206615446375 24.998134256100283 1.0298263293089054 1.2560408052968979 0.5384903778926778 0.10819358251130999 429.918691290933 264532.9386657243 0.03441970816228477 0.03902879398040446 4.988085000284453e-07 6.30206615446375 0.2262144759879925 ASTNS(ph)ETNRGESEK ddPTM_PC-9_AZD4547_30min_R2 1 ASTNSETNRGESEK 14 1 J3QKN5;J3KS94;J3QQK6;P02686-2;P02686 J3QKN5 MBP Myelin basic protein 1 AS(0.001)T(0.002)NS(0.924)ET(0.041)NRGES(0.032)EK 97.291 0.020078 0.0 6798.1 8779.5 6518.5 10083.0 10640.0 10916.0 7746.9 10721.0 9880.7 10272.0 True False 8959.754390735858 11617.301682520083 6432.060430887764 7758.520130797096 9162.819659768838 10233.420794366222 8436.359092266124 9064.315794071283 10402.973630151157 9912.380406553462 0.903895333235215 1.1719991773963225 0.6488916049504393 0.7827100870410133 0.9243813578533507 1.0323878195393417 0.851093152830224 0.914443899679083 1.0494929778192676 1.0 13.275015839384068 -6.517847391566513 24.59263726681518 0.959142211047239 0.8781544259711344 0.094510612010957 0.13324731605250903 548.7397728498019 2682193.377648261 0.04555524745930347 0.0468113141046126 3.03495746239269e-07 6.517847391566513 -0.0809877850761046 ASTNS(ph)ETNRGESEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASTNSETNRGESEK 14 1 J3QKN5;J3KS94;J3QQK6;P02686-2;P02686 J3QKN5 MBP Myelin basic protein 1 AS(0.001)T(0.008)NS(0.99)ET(0.001)NRGESEK 122.31 0.0018401 0.0 8145.3 11225.0 6381.2 8602.3 10959.0 10983.0 8518.6 6225.7 8662.6 11115.0 True False 9524.13841299183 12339.343816559393 6533.352008835763 8120.341020032885 8811.662619839743 10407.032145533505 7711.6565386768225 6062.281971674409 8789.274136970893 13130.061513708406 0.7253689103473109 0.9397780660567762 0.49758731153046265 0.6184541490193983 0.6711059663079224 0.7926110730454744 0.5873282871238256 0.46171009673832064 0.6694008347024478 1.0 13.68058605475315 -8.598497946452788 20.43860258097318 1.0000000004582035 0.6599940117552743 0.37207075210544327 0.1315150447262232 19187.80684289492 5186133.650712392 0.13367210500691082 0.034513989109375594 2.5205890981337986e-09 8.598497946452788 -0.3400059887029292 ASTSDYQVISDRQT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 ASTSDYQVISDRQTPK 16 1 Q8NFH5-2;Q8NFH5;Q8NFH5-3 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 ASTSDYQVIS(0.002)DRQT(0.998)PK 79.462 0.006413299999999999 51421000.0 60004.0 54074.0 77073.0 67984.0 79062.0 79325.0 66945.0 93719.0 79595.0 66817.0 True False 79084.02383926597 71552.36302529661 76050.96166139634 52311.3391423296 68085.60600945902 74364.79521006772 72902.97531035075 79236.88199837368 83802.22920358684 64477.75716751199 1.226531866389322 1.1097216492720883 1.1794914246756039 0.8113082935938006 1.0559549370269488 1.1533402909296209 1.1306685981795273 1.2289025778691054 1.2997075718044944 1.0 15.976513940729474 -6.899031006079026 3.7334420393160737 1.1796215584550083 1.0698449537655093 0.099391346262233 0.12524132348825315 0.4989658680539094 13.327782473588337 0.04819335667720265 0.04198134267067606 1.2617374507206363e-07 6.899031006079026 -0.10977660468949901 ASTSDYQVISDRQT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASTSDYQVISDRQTPK 16 1 Q8NFH5-2;Q8NFH5;Q8NFH5-3 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 ASTSDYQVIS(0.01)DRQT(0.99)PK 60.826 0.031662 34153000.0 101980.0 70638.0 67541.0 83671.0 90704.0 64463.0 80061.0 86040.0 57595.0 64946.0 True False 119243.19980318773 77650.47380972146 69151.43359066894 78983.1851350419 72931.20232411216 61082.44679937413 72477.04248855503 83781.54116691556 58437.21791596497 76720.19568774686 1.5542608922494225 1.0121255963131384 0.9013458968759285 1.0294966589567298 0.9506128297814047 0.7961716762035023 0.9446931389948278 1.0920402433266536 0.7616927641035475 1.0 16.227318779746238 -4.760258527126685 3.7987016882237703 0.9377628857037543 1.631639841861009 0.7936599753890184 0.09420339830350259 0.11596399680738569 2.927640870081601 0.023072956303031553 0.23349362740434934 1.7367666572833068e-05 4.760258527126685 0.6938769561572546 ASTSDYQVISDRQT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 ASTSDYQVISDRQTPK 16 1 Q8NFH5-2;Q8NFH5;Q8NFH5-3 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 ASTSDYQVIS(0.001)DRQT(0.999)PK 75.319 0.0089535 39107000.0 120410.0 95762.0 121220.0 96569.0 105430.0 78771.0 92876.0 71773.0 97376.0 66665.0 True False 118692.93131951042 95540.26897259978 111253.75952273153 103671.00640474027 99228.81468335503 75402.1479541695 97684.66483424176 75107.83560021842 86408.48946526142 78187.95642447117 1.518046215137579 1.2219307594372386 1.4229014877783848 1.325920399324997 1.269106128630042 0.9643703634460286 1.2493569253035055 0.9606061986384294 1.1051380982022623 1.0 16.254658780626777 -6.586266539431863 4.333782202619219 1.0661116985294368 1.359258310106826 0.6690451129097703 0.1054638817862835 0.1304785209507981 4.934030903328605 0.033573156962321736 0.03395383076898419 2.592587725606056e-07 6.586266539431863 0.2931466115773893 ASTSSSSSSSSNQQTEKET(ph)NTPK ddPTM_PC-9_AZD4547_30min_R2 1 ASTSSSSSSSSNQQTEKETNTPK 23 1 C9J2P0;P51965-3;P51965 C9J2P0 UBE2E1 Ubiquitin-conjugating enzyme E2 E1 1 ASTSSSS(0.001)S(0.007)S(0.034)S(0.034)SNQQT(0.001)EKET(0.461)NT(0.461)PK 72.47399999999999 0.0004943 16090000.0 7256.7 6380.5 5247.2 7333.3 8441.9 8190.9 7491.0 8095.3 9991.0 10354.0 True False 9564.179651263286 8442.871847521996 5177.618699540425 5642.720983355581 7269.887902800992 7678.721728158139 8157.684488010116 6844.357396487753 10519.10386296924 9991.50961151232 0.9572306911703653 0.8450046265074932 0.5182018434506354 0.5647515943790896 0.7276065565131973 0.7685246801254775 0.8164616564658806 0.6850173459875988 1.0528042580121246 1.0 13.286486955122692 -8.263582911524281 24.897589821916903 1.0264021719986498 0.7296315946775652 0.4751255397154358 0.1222460881419014 170.02846457072783 1974840.646427972 0.1095080583650938 0.033585935403548484 5.450258344162272e-09 8.263582911524281 -0.2967705773210846 ASTSSSSSSSSNQQTEKET(ph)NTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASTSSSSSSSSNQQTEKETNTPK 23 1 C9J2P0;P51965-3;P51965 C9J2P0 UBE2E1 Ubiquitin-conjugating enzyme E2 E1 1 AST(0.001)SSS(0.001)S(0.001)S(0.003)S(0.014)S(0.014)S(0.014)NQQT(0.003)EKET(0.551)NT(0.397)PK;ASTSSSSS(0.001)S(0.011)S(0.011)S(0.003)NQQT(0.19)EKET(0.594)NT(0.19)PK 70.89699999999999 0.00067074 22978900.0 16941.7 15013.78 13604.1 20480.5 20750.3 21719.3 21593.6 22097.1 18474.6 16081.9 True False 19809.59519617247 16504.248855784677 13928.473337836562 19333.04398367687 16684.427672274902 20580.301673357542 19548.097883874325 21517.07453881275 18744.756074490604 18997.421165749656 1.0427518042231478 0.8687625921322466 0.7331770568390686 1.0176667567139221 0.8782469750344412 1.0833208093770987 1.0289869195044998 1.1326313372262211 0.9867000321225399 1.0 14.213515970532336 -6.760121636539206 24.999984541043382 1.0535334832081018 0.9023012064463596 0.3763484508710607 0.08855554979355458 36.02976834626804 683556.1255017542 0.030008032383926284 0.0284572193401715 1.7373141762849695e-07 6.760121636539206 -0.15123227676174222 ASTSSSSSSSSNQQTEKET(ph)NTPK ddPTM_PC-9_Lapatinib_30min_R1 1 ASTSSSSSSSSNQQTEKETNTPK 23 1 C9J2P0;P51965-3;P51965 C9J2P0 UBE2E1 Ubiquitin-conjugating enzyme E2 E1 1 ASTSSSSSSSSNQQTEKET(0.563)NT(0.436)PK 66.36 0.0011786 20607000.0 20187.0 16807.0 16261.0 20324.0 18530.0 15295.0 12952.0 9851.7 16376.0 13076.0 True False 19899.129678157602 16768.084424119003 14924.083349275208 21818.6947588765 17440.10183138168 14640.868504386423 13622.591185377289 10309.445947399052 14531.562433075087 15336.169177325217 1.2975293535219212 1.093368508800157 0.9731298068451615 1.4226952315533794 1.1371876268271193 0.9546626889088569 0.8882655784417479 0.6722308438434378 0.9475353502594537 1.0 13.90465053650526 -6.861974605790595 2.756064341124157 0.8545057067319776 1.1844438603259373 0.5378596333378625 0.13684844833808557 0.21034776324495533 3.2366698902954467 0.053374726263261105 0.04671249528627717 1.374122320794578e-07 6.861974605790595 0.3299381535939597 ASTSSSSSSSSNQQTEKETNT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 ASTSSSSSSSSNQQTEKETNTPK 23 1 C9J2P0;P51965-3;P51965 C9J2P0 UBE2E1 Ubiquitin-conjugating enzyme E2 E1 1 ASTSSSSSS(0.001)S(0.001)SNQQT(0.006)EKET(0.054)NT(0.939)PK;ASTSSSSSS(0.001)S(0.001)SNQQTEKET(0.012)NT(0.985)PK;ASTSSSSSSSSNQQTEKET(0.046)NT(0.954)PK 75.529 0.00027715 27852000.0 35837.3 28447.2 35563.3 40083.6 48873.9 47078.8 40344.8 37361.1 39917.6 45390.9 True False 47232.81593785298 37642.201084684246 35091.70740535258 30842.945305446643 42088.60260992254 44134.95519364313 43935.40904176622 31587.800467668738 42027.56284260444 43801.778406914666 1.0783310097381043 0.8593760905091915 0.8011480054383571 0.7041482429986836 0.9608879853900709 1.0076064671080995 1.00305080386486 0.7211533781624311 0.9594944399784886 1.0 15.418701825785726 ASTSSSSSSSSNQQTEKETNT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASTSSSSSSSSNQQTEKETNTPK 23 1 C9J2P0;P51965-3;P51965 C9J2P0 UBE2E1 Ubiquitin-conjugating enzyme E2 E1 1 ASTSSSSSSSSNQQTEKET(0.009)NT(0.99)PK;ASTSSSSSSSSNQQT(0.003)EKET(0.116)NT(0.881)PK 89.773 1.5735e-05 26068100.0 15549.1 13564.0 15408.6 22861.6 20339.2 20563.1 23108.5 21935.3 19669.6 15471.8 True False 18181.255521276216 14910.544278646907 15775.999461440913 21580.73867030724 16353.879766168857 19484.734836731324 20919.49558894812 21359.52161737149 19957.23068877271 18276.714865298596 0.9947769965923348 0.8158219017224518 0.863174787028838 1.1807777726664592 0.8947931773679654 1.066096121777681 1.1445982356855218 1.1686740081460767 1.0919484620655135 1.0 14.15771915708651 -6.0435027934730154 0.8651749703620509 1.1058330468545894 0.8805199640645669 0.33494961156834446 0.10111379613279826 0.7226796051348297 1.1033750293402442 0.04866688932355297 0.10664819355984624 9.046846185985662e-07 6.0435027934730154 -0.2253130827900225 ASTSSSSSSSSNQQTEKETNT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 ASTSSSSSSSSNQQTEKETNTPK 23 1 C9J2P0;P51965-3;P51965 C9J2P0 UBE2E1 Ubiquitin-conjugating enzyme E2 E1 1 ASTSSSSSS(0.001)S(0.001)S(0.001)NQQTEKET(0.034)NT(0.963)PK;ASTSSSSSSSSNQQTEKET(0.008)NT(0.992)PK 92.833 9.8044e-06 23054900.0 39434.0 32031.0 36916.0 40390.0 43974.0 33177.0 23312.7 24967.0 33046.0 33724.0 True False 38871.663928690075 31956.834187478766 33880.908979880915 43360.41533709022 41387.535776210374 31758.0970493644 24519.71753608283 26127.05796651461 29324.01149019293 39553.14846559465 0.9827704098575778 0.807946659803238 0.8565919602924218 1.0962569863384537 1.046377782345478 0.8029221005500793 0.6199182236380332 0.660555707448707 0.7413824847774244 1.0 15.271504918619462 -6.951322485156266 6.232174613390188 0.7247989568046246 0.9505702755148892 0.3741860057856481 0.1232343917086159 0.19245835305485035 17.25603293701794 0.04493011711925545 0.03930692625968296 1.1186069539526903e-07 6.951322485156266 0.22577131871026457 ASTVS(ph)PGGYMVPK ddPTM_PC-9_AZD4547_30min_R2 2 ASTVSPGGYMVPK 13 0 Q5TGY3 Q5TGY3 AHDC1 AT-hook DNA-binding motif-containing protein 1 1 AS(0.001)T(0.031)VS(0.955)PGGY(0.013)MVPK;ASTVS(1)PGGYMVPK 136.01 4.7078999999999994e-05 8724900.0 51584.0 53516.0 67805.0 93585.0 83644.0 74345.0 58676.0 83256.0 66902.0 74470.0 True False 67986.63898614586 70814.00043758127 66905.86139700002 72010.42412383683 72031.47440053608 69696.19539732109 63898.050329526304 70390.69823255275 70438.30313685999 71862.82796690398 0.9460612796570812 0.9854051453443254 0.9310218271372946 1.0020538595698019 1.0023467825912693 0.9698504410293912 0.8891669328537167 0.979514725818622 0.9801771671064762 1.0 16.132958089361424 -5.730949556345399 0.0023335110932761736 1.928683665811582 5.7841394021088696e-05 0.046183482526540476 0.03384687932501412 483082.27191707364 248.57778520667316 101504.28631257245 103948.49518157852 1.8580202531109439e-06 5.730949556345399 -1.928625824417561 ASTVS(ph)PGGYMVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASTVSPGGYMVPK 13 0 Q5TGY3 Q5TGY3 AHDC1 AT-hook DNA-binding motif-containing protein 1 1 AST(0.005)VS(0.995)PGGYMVPK;AS(0.001)T(0.026)VS(0.972)PGGY(0.002)MVPK 119.21 0.00020377 22705000.0 75073.0 75656.0 83053.0 87741.0 100122.0 93162.0 83590.0 75760.0 77256.0 68478.0 True False 87781.37614066206 83166.62768691452 85033.29850025657 82825.15623015993 80503.8128317908 88276.42071767202 75671.7500608075 73771.38027435516 78385.72284600722 80892.5193284503 1.0851606164500913 1.028112715209556 1.0511886538604804 1.0238914168795075 0.995194778208338 1.0912803983671302 0.935460419443178 0.9119678913054869 0.9690107749980605 1.0 16.303718672726937 -7.2761503490856585 24.97553490932873 0.9467737542357391 1.041948786741648 0.6283222751975157 0.03428796977682672 503.7088956117736 855167.7763192826 0.013906005276629664 0.009421713069677205 5.2948011061199876e-08 7.2761503490856585 0.09517503250590886 ASTVS(ph)PGGYMVPK ddPTM_PC-9_Lapatinib_30min_R1 2 ASTVSPGGYMVPK 13 0 Q5TGY3 Q5TGY3 AHDC1 AT-hook DNA-binding motif-containing protein 1 1 AST(0.003)VS(0.997)PGGYMVPK;ASTVS(1)PGGYMVPK 166.24 0.0002652 7303000.0 71545.0 64583.0 69051.0 61725.0 64268.0 68996.0 65449.0 63126.0 65645.0 57438.0 True False 70524.7551802537 64433.4620314677 63373.8933245681 66264.46240856395 60487.882595749485 66045.20191753155 68837.62897558342 66059.06441279307 58251.36882750449 67366.08176867582 1.0468881865866009 0.9564674141613541 0.9407388950152058 0.9836472697952858 0.8978981856693854 0.9803925088640311 1.0218440373593443 0.9805982874234717 0.8646987816143178 1.0 16.039734769459617 -4.760466967260845 24.416929464876013 0.9588742226150977 1.0468883192236031 0.25896335648843727 0.04486309935750095 25.866435710789712 649043.4016208011 0.011094937252976188 0.06541255419099885 1.7359332941391282e-05 4.760466967260845 0.08801409660850545 ASVALT(ph)PTAPSR ddPTM_PC-9_AZD4547_30min_R2 2 ASVALTPTAPSR 12 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7;H7BZ26 E9PHV5 SSFA2 Sperm-specific antigen 2 1 AS(0.001)VALT(0.858)PT(0.14)APSR;AS(0.013)VALT(0.98)PT(0.007)APSR 184.98 0.00018125 81470000.0 222410.0 226677.0 254640.0 395480.0 347630.0 293070.0 232670.0 340920.0 262610.0 289040.0 True False 293131.7535846139 299945.9073396671 251263.3072211794 304308.19610509113 299367.5750305861 274744.2865706217 253377.1792584858 288238.6475622403 276491.0284710592 278920.79757692834 1.0509497898010496 1.0753802152632232 0.900841060989291 1.0910200987115735 1.073306750989117 0.9850261757366633 0.9084198147275215 1.0334067952847512 0.9912886771908826 1.0 18.089495986581568 -6.868608723694989 8.870915227619212 0.9805607790879274 1.035572712547724 0.18339379068326034 0.057416409356157015 0.5010529490045743 38.08200721754802 0.02072699831687325 0.01828654188640786 1.353291257803691e-07 6.868608723694989 0.055011933459796714 ASVALT(ph)PTAPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASVALTPTAPSR 12 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7;H7BZ26 E9PHV5 SSFA2 Sperm-specific antigen 2 1 ASVALT(0.71)PT(0.29)APSR;AS(0.003)VALT(0.936)PT(0.061)APSR;ASVALT(0.71)PT(0.29)APSR 135.1 0.00014517 63118000.0 228422.0 242360.0 279707.0 270608.0 363601.0 247700.0 266925.0 197480.0 186846.0 170090.0 True False 267089.3330598527 266419.8990985603 286376.275674705 255446.71108297273 292355.9941816176 234710.17594907113 241639.93163035082 192296.35924735578 189578.26927209637 200925.97056830124 1.3292922378546401 1.3259604935340876 1.4252825300020457 1.2713474040238024 1.4550433343918394 1.1681425516333914 1.2026316505869985 0.957050791908396 0.9435229738390268 1.0 17.61630452526046 -7.42911098883044 1.3569017853151932 0.9507276835883577 1.3548904486511275 0.8423576162309757 0.07087909152652075 0.15237078323658237 0.5373338798912992 0.04547941866911034 0.02295466551858541 3.722965495330965e-08 7.42911098883044 0.4041627650627698 ASVALT(ph)PTAPSR ddPTM_PC-9_Lapatinib_30min_R1 2 ASVALTPTAPSR 12 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7;H7BZ26 E9PHV5 SSFA2 Sperm-specific antigen 2 1 AS(0.001)VALT(0.968)PT(0.031)APSR;ASVALT(0.659)PT(0.333)APS(0.008)R 89.663 0.017821 5161200.0 41096.0 41809.0 43378.0 45938.0 42415.0 41397.0 36504.0 29499.0 34239.0 31567.0 True False 40509.96350391661 41712.19382923728 39811.628283922284 49316.43376467567 39920.23309109845 39626.54681112031 38393.99850455624 30869.63123139404 30382.643267346004 37023.31388961645 1.0941744335662513 1.1266466841299116 1.0753123937694795 1.3320372647275893 1.0782458104674004 1.0703133417301673 1.0370222022541373 0.8337889828941468 0.8206354341464585 1.0 15.176146413551644 -7.437533635640355 1.771468517783941 0.8706362962494392 1.1418726300684903 0.6127457049322325 0.08603582042784451 0.23393037404325673 1.431225356998384 0.05173911490647754 0.027606018693203428 3.651458460067724e-08 7.437533635640355 0.2712363338190511 ASVALTPT(ph)APSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASVALTPTAPSR 12 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7;H7BZ26 E9PHV5 SSFA2 Sperm-specific antigen 2 1 ASVALT(0.313)PT(0.687)APSR 107.39 0.0038088 11354000.0 36992.0 40411.0 44584.0 42408.0 60659.0 34287.0 35434.0 31917.0 31856.0 29241.0 True False 43254.014974696285 44422.73701300507 45647.051645761574 40032.01724859102 48773.304394274965 32488.92936118615 32077.43500005571 31079.21256885685 32321.83373436896 34542.16182837138 1.252209262107312 1.2860439144986642 1.3214879796049457 1.15893201611112 1.411993396262036 0.9405586576373804 0.928645843286761 0.8997471763139554 0.9357212178833941 1.0 15.076070756610594 -6.776015446352512 24.99561498729162 0.9339006138618 1.2810257407600316 0.8810655615621155 0.06337431870917629 70.76731076374327 121353.84309686671 0.020940224074089926 0.018546944868912472 1.6748833051612749e-07 6.776015446352512 0.3471251268982316 ASVALTPT(ph)APSR ddPTM_PC-9_Lapatinib_30min_R1 2 ASVALTPTAPSR 12 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7;H7BZ26 E9PHV5 SSFA2 Sperm-specific antigen 2 1 ASVALT(0.141)PT(0.858)APSR;ASVALT(0.177)PT(0.822)APS(0.001)R 110.8 0.0028101 73768000.0 141385.0 125783.0 132313.0 104234.0 114416.0 99895.0 89737.0 77922.0 93053.0 74610.0 True False 139368.82397316664 125491.75719158466 121434.73588294993 111899.71607443088 107686.27583051096 95622.72371661854 94383.14277348682 81542.54058824673 82572.39124846955 87506.23908842429 1.5926729959487307 1.434089254650475 1.3877266026739097 1.2787627172658762 1.2306125477715357 1.0927532106595577 1.0785875813736376 0.931848305191687 0.9436171878559524 1.0 16.41709826256342 -5.997810141322235 0.5022724070331341 0.9327613874750552 1.652581508979475 0.9606356091492069 0.04232887619685719 0.2733509440044936 0.11943762971738368 0.03354326677076978 0.10255012233157662 1.0050550699170755e-06 5.997810141322235 0.7198201215044199 ASVALTPTAPS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 ASVALTPTAPSR 12 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7;H7BZ26 E9PHV5 SSFA2 Sperm-specific antigen 2 1 ASVALTPTAPS(1)R;ASVALTPTAPS(1)R 122.66 0.00039051 67565000.0 177549.0 157216.0 223410.0 168168.0 191789.0 208932.0 240282.0 236440.0 188402.0 212530.0 True False 234005.88875138125 208032.99747355498 220447.43742649892 129399.46576969996 165162.4078691172 195867.4490114076 261666.63251208747 199903.63085068695 198360.54508969383 205089.38938909737 1.1409946143406924 1.0143528053461262 1.0748846543604658 0.6309417866772336 0.8053191262653263 0.9550345319903711 1.2758662614946463 0.9747146424597718 0.9671906756393062 1.0 17.645893328167247 -9.69529810302043 17.641428323943828 1.000014738946719 0.9779113823404998 0.0004536282727860552 0.16641199888751698 0.0 0.0 0.17416753699769646 0.04224183244677497 2.016981417101724e-10 9.69529810302043 -0.022103356606219315 ASVALTPTAPS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASVALTPTAPSR 12 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7;H7BZ26 E9PHV5 SSFA2 Sperm-specific antigen 2 1 ASVALTPT(0.003)APS(0.997)R;ASVALTPT(0.001)APS(0.999)R;ASVALTPT(0.024)APS(0.976)R 100.22 0.0031005 56607000.0 130914.0 165285.0 155208.0 121980.0 137941.0 130414.0 147574.0 105432.0 115128.0 119291.0 True False 153075.15453063877 181693.40246948984 158908.74734961768 115145.85606449565 110912.45126775376 123574.8602592741 133594.72237676303 102664.52171443794 116811.5291992222 140917.51399296388 1.0862748723929514 1.2893599760677152 1.1276720887763612 0.8171152953368519 0.7870735732202294 0.8769304592291082 0.9480349077364048 0.7285433783593717 0.8289354948814573 1.0 17.104491403192583 -5.695002569464347 4.77424240404845 0.8455882436746411 1.1906690682074152 0.7319802091271745 0.08678945761764481 0.0940239121069183 4.118666383145097 0.023281823960101828 0.04068644909963489 2.0183544222333365e-06 5.695002569464347 0.3450808245327741 ASVALTPTAPS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 4 ASVALTPTAPSR 12 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7;H7BZ26 E9PHV5 SSFA2 Sperm-specific antigen 2 1 ASVALT(0.001)PT(0.003)APS(0.996)R;ASVALT(0.001)PT(0.006)APS(0.993)R;ASVALTPTAPS(1)R;ASVALTPTAPS(1)R 120.59 0.00048587 89208000.0 225821.0 260443.0 232529.0 221219.0 254843.0 259021.0 286202.0 283670.0 291229.0 203839.0 True False 222600.7511295009 259839.96023507055 213411.36320789697 237488.1832249505 239853.63578061562 247943.27563744233 301020.1391628587 296850.343788248 258427.7232426737 239072.29955160516 0.9311022295222087 1.0868676995302944 0.8926645354069173 0.9933739026661568 1.0032682005839904 1.0371058299203848 1.2591175963398542 1.2416760299918022 1.0809605451044342 1.0 17.86708745427873 -7.0656424688979955 5.209912325159742 1.1652827218792714 0.9858872010185384 0.4488099316879778 0.08454065286764853 0.18019390961388154 9.56712536249047 0.031683077997672206 0.024749209365558376 8.597209919379533e-08 7.0656424688979955 -0.17939552086073296 ASVGFGGSCFQK ddPTM_PC-9_Lapatinib_30min_R1 2 ASVGFGGSCFQK 12 0 O60701;O60701-2;O60701-3 O60701 UGDH UDP-glucose 6-dehydrogenase 0 ; 171.62 4.7002999999999996e-18 7040900.0 27110.0 26635.0 30788.0 27315.0 29189.0 29776.0 26832.0 21195.2 24339.0 24620.0 False True 26723.406428634873 26573.328293949507 28256.72948511685 29323.83622016884 27472.160407781976 28502.54989124616 28221.229670015695 22180.00636888174 21597.685518967664 28875.534195912092 0.9254688154797186 0.9202714004754756 0.9785699302878059 1.0155253240066537 0.9513992094965712 0.9870830336112453 0.9773405222061995 0.7681245381781288 0.7479579554246046 1.0 14.817560016109812 -7.751982727673047 24.998466289673658 0.818530933045783 0.9661470801315519 0.40450920082010433 0.06898212232994799 155.15078317720273 410140.7273631486 0.03175524480091802 0.018021390700096136 1.7701793587252775e-08 7.751982727673047 0.14761614708576898 ASVITQVFHVPLEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASVITQVFHVPLEER 15 0 Q00341;A0A024R4E5;Q00341-2;C9JK79;C9JIZ1;C9J5E5;C9JZI8;C9JES8;C9JHZ8;C9JHS7;C9JT62 Q00341 HDLBP Vigilin 0 105.17 0.0019506 0.0 8812.8 8808.9 11783.0 10303.0 13287.0 11141.0 10932.0 11408.0 9779.2 7780.1 False True 10304.632979265882 9683.389376008023 12063.951407276341 9725.756312776683 10683.507731527578 10556.746347390406 9896.441819173931 11108.55208777514 9922.202299571227 9190.57054276229 1.1212179843808425 1.0536222240994422 1.312644449128012 1.0582320507224503 1.1624422751361172 1.1486497272689995 1.076803858163901 1.2086901499845717 1.0796067832138132 1.0 13.165938710231236 -8.527856655055981 21.965237984735296 0.9999999960332817 1.1414875005919767 0.2731606867928681 0.07317643120202255 130.1298030105589 574209.5072541612 0.06662317252884635 0.017202029185495762 2.9658101349436702e-09 8.527856655055981 0.14148750455869497 ASVLDTSMS(ph)AGSGSPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASVLDTSMSAGSGSPSK 17 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 ASVLDT(0.003)S(0.038)MS(0.613)AGS(0.192)GS(0.154)PSK 101.2 0.007933299999999999 0.0 20912.0 20561.0 20207.0 23394.0 24633.0 22489.0 22248.0 20748.0 19520.0 17366.0 True False 24451.98856917303 22602.160197084886 20688.811515474248 22083.31002437131 19806.340479470073 21309.63725037814 20140.50837842861 20203.386984323144 19805.443071788115 20514.318330819642 1.1919474083834234 1.1017748595198789 1.0085059216611871 1.0764827603944556 0.9654885997217885 1.038768966471757 0.9817780953594037 0.9848432035867665 0.9654448542915243 1.0 14.324343595340453 -1.5228787453197525 0.5292784406167698 0.9869645587562685 9.049536280132543 0.8160205171629078 0.029608203532676035 46.806738038612785 0.45706666091189324 0.014543628918463251 425.3770408634762 0.02999999999727731 1.5228787453197525 8.062571721376274 ASVLDTSMS(ph)AGSGSPSKTVTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASVLDTSMSAGSGSPSKTVTPK 22 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 AS(0.001)VLDT(0.136)S(0.136)MS(0.71)AGS(0.008)GS(0.007)PS(0.002)KTVTPK 62.617 0.007536399999999999 9194100.0 26384.0 7581.9 17282.0 39160.0 37851.0 71175.0 37647.0 70196.0 62780.0 45583.0 True False 30850.29009224664 8334.580924968519 17694.068422349967 36965.99215843296 30434.368265677003 67442.45770357351 34080.80361932319 68353.42937880996 63698.0387319087 53846.83706517056 0.5729266893598353 0.15478311037807507 0.32859995845131856 0.6865025723552378 0.5652025248733261 1.2524868939274603 0.6329211793456941 1.2694047246652973 1.1829485667805386 1.0 15.716573983661384 -6.405739693506088 1.0570362825212223 1.0888331401413147 0.3234746644837604 0.6519072465043296 0.21958548310993833 0.30255708216127786 0.7165810293937158 0.10006058597727269 0.13074378169667317 3.928803486214594e-07 6.405739693506088 -0.7653584756575543 ASVLDTSMS(ph)AGSGSPSKTVTPK ddPTM_PC-9_Lapatinib_30min_R1 1 ASVLDTSMSAGSGSPSKTVTPK 22 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 ASVLDT(0.031)S(0.138)MS(0.794)AGS(0.037)GSPSKTVTPK 85.51 0.00034697 5305500.0 188970.0 38886.0 66352.0 50402.0 35996.0 37826.0 25690.0 25464.0 57718.0 26621.0 True False 186275.25314714637 38795.96185614873 60896.79468612679 54108.73121614316 33878.786050858886 36208.270156712715 27020.102497864595 26647.15040090233 51217.19104251511 31222.404379747204 5.966076503319395 1.2425680413425881 1.950419767339515 1.7330097502433686 1.0850793436278334 1.159688719559332 0.8654074865352623 0.8534624712691036 1.6403986835728055 1.0 14.930294020426189 -4.761096942174226 24.99998132255851 1.2886612707989948 5.966081734663343 0.9395394370585777 0.3565334124473455 1.9457201258884895 141847.91751186847 0.09700626684528314 0.5514824593226247 1.7334170253689087e-05 4.761096942174226 4.6774204638643475 ASVLDTSMSAGS(ph)GSPSK ddPTM_PC-9_AZD4547_30min_R2 2 ASVLDTSMSAGSGSPSK 17 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 ASVLDTSMS(0.025)AGS(0.929)GS(0.046)PSK;ASVLDTSMS(0.092)AGS(0.705)GS(0.202)PSK 210.57 8.1857e-18 100915000.0 126391.0 111151.0 122920.0 140842.0 147058.0 137440.0 141663.0 134843.0 133085.0 144115.0 True False 166580.70890388446 147078.3870737274 121290.00048549884 108373.05288720859 126641.53510585411 128845.85507307561 154270.73256240552 114006.11273388224 140119.60140158766 139069.57771519225 1.1978227851171999 1.0575885070632545 0.872153367243948 0.7792721792047959 0.910634354302922 0.9264848372297906 1.1093061120696326 0.8197775142983552 1.0075503478449168 1.0 17.08544733083975 -3.1095978633181 8.431655425680502 0.9588049972247492 1.0146431999392727 0.0 0.12491820927720548 0.0 0.0 0.029712082365253873 0.0 0.0007769662185725339 3.1095978633181 0.055838202714523444 ASVLDTSMSAGS(ph)GSPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASVLDTSMSAGSGSPSK 17 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 ASVLDTSMS(0.003)AGS(0.64)GS(0.357)PSK;ASVLDTS(0.005)MS(0.138)AGS(0.832)GS(0.025)PS(0.001)K 159.54 2.5726e-05 109542000.0 151548.0 153749.0 142292.0 170515.0 172204.0 137063.0 168264.0 142590.0 136507.0 122316.0 True False 177202.08319056206 169012.18462825785 145684.7809254149 160961.5973670891 138461.86237675705 129875.17499437845 152324.8157941346 138847.16358659344 138503.15662912797 144490.92254707642 1.2263890358429128 1.1697079764522382 1.0082625147469004 1.113991069678764 0.9582737789749038 0.8988466036824145 1.0542172000078815 0.9609403908495069 0.9585595703010507 1.0 17.140619334583683 -4.873490200858826 0.7585872648237808 0.9726211376210991 1.371608622679341 0.7162533768573455 0.05302156336686363 1.3223816414281586 0.633353624727263 0.02173536634914281 0.43991975967803026 1.3381654083164075e-05 4.873490200858826 0.3989874850582418 ASVLDTSMSAGS(ph)GSPSK ddPTM_PC-9_Lapatinib_30min_R1 2 ASVLDTSMSAGSGSPSK 17 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 ASVLDTSMS(0.002)AGS(0.938)GS(0.06)PSK;ASVLDTSMS(0.001)AGS(0.996)GS(0.003)PSK 184.21 3.2694e-08 101678000.0 122335.0 146309.0 138156.0 137199.0 148205.0 126471.0 124212.0 115880.0 130956.0 106461.0 True False 120590.48046650852 145970.23049969831 126797.34697758232 147289.07214244705 139487.87328224094 121062.13014830033 130643.08958601631 121264.20784073843 116206.35625218484 124862.64199963432 0.9657851102242551 1.1690464670780056 1.0154946663546784 1.179608806794897 1.1171305608177782 0.969562458470604 1.0462944519978916 0.9711808584115461 0.9306735336620954 1.0 16.929982372009277 -6.76344460468482 24.999647323911976 0.9856630643697097 1.0947414938389644 0.3903394990192337 0.06596158192949107 54.465300784573806 679026.4025641653 0.021893566965534277 0.02027340337701294 1.7240719865686894e-07 6.76344460468482 0.10907842946925461 ASVLDTSMSAGSGS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 2 ASVLDTSMSAGSGSPSK 17 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 ASVLDT(0.008)S(0.034)MS(0.079)AGS(0.259)GS(0.564)PS(0.057)K;ASVLDTS(0.002)MS(0.08)AGS(0.375)GS(0.543)PSK 159.44 2.5675e-05 94058000.0 124547.0 103251.0 119430.0 137461.0 120835.0 131934.0 123755.0 142858.0 115864.0 119959.0 True False 164150.3552614671 136624.86656664746 117846.28016582415 105771.49020127933 104059.14601392574 123684.14612348052 134768.95525479785 120782.57865025983 121988.33449895596 115759.271922678 1.418032029184774 1.1802498780219242 1.018028864629869 0.9137193802664026 0.8989270948717833 1.0684599520122757 1.164217371242776 1.0433944222708758 1.053810485093917 1.0 16.820768227500245 -4.876590657497802 2.295507840810857 1.02065491412003 1.4718671775873993 0.7460760137174407 0.07198577654792032 0.27036458478144654 2.0248729607289397 0.022110751883082744 0.23067825326394922 1.3286461778004525e-05 4.876590657497802 0.4512122634673692 ASVLDTSMSAGSGS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASVLDTSMSAGSGSPSK 17 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 ASVLDTSMS(0.003)AGS(0.022)GS(0.974)PS(0.001)K;ASVLDTSMSAGS(0.004)GS(0.937)PS(0.059)K;ASVLDT(0.003)S(0.014)MS(0.074)AGS(0.097)GS(0.809)PS(0.003)K 152.68 5.8679999999999993e-08 105362000.0 277895.0 282957.0 270284.0 301805.0 330132.0 256932.0 303337.0 269167.0 246669.0 199835.0 True False 324937.1348235618 311047.100962334 276728.5956177781 284895.8443150117 265445.00447239116 243458.03361706412 274602.7233903006 262101.65145601128 250276.06747309948 236063.5036070101 1.3764818782174195 1.3176416354480356 1.172263358754794 1.2068610351106874 1.1244643937603092 1.031324325433906 1.1632578488178722 1.1103014546981753 1.0602065276882018 1.0 17.84881548662952 -1.5228787452815116 0.3120438899516134 1.0475814524192588 4.274359147395285 0.8513830916331859 0.043918008372809 20.623322557792118 0.2944785905729938 0.043688076811102504 37.65026754603016 0.029999999999918904 1.5228787452815116 3.2267776949760263 ASVLDTSMSAGSGS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 2 ASVLDTSMSAGSGSPSK 17 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 ASVLDTSMSAGS(0.117)GS(0.83)PS(0.053)K;ASVLDTSMS(0.001)AGS(0.208)GS(0.734)PS(0.056)K 162.82 2.7462e-05 96550000.0 184499.0 228980.0 228190.0 226590.0 247800.0 212568.0 196017.0 188899.0 208142.0 170045.0 True False 181868.01042702742 228449.81087848876 209429.09903887275 243254.1844820818 233224.89119354452 203476.96216021018 206165.801141453 197675.93714970292 184698.8561275719 199437.0516792795 0.911906834240082 1.1454732656490807 1.050101258895773 1.2197040742121774 1.169416060003736 1.0202565694133274 1.0337387130701983 0.9911695719789887 0.9261010156958771 1.0 17.605573934866214 -7.304051436247273 1.7290106786609942 0.9717315855729136 1.102515121210882 0.28998044309371585 0.08152270582138392 0.46753820877117985 2.7221236675955622 0.046228876079087745 0.02746440140968573 4.965335103579469e-08 7.304051436247273 0.1307835356379683 ASVS(ph)PMDEPVPDSESPIEK ddPTM_PC-9_AZD4547_30min_R2 12 ASVSPMDEPVPDSESPIEK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 AS(0.042)VS(0.958)PMDEPVPDSESPIEK;AS(0.115)VS(0.88)PMDEPVPDS(0.003)ES(0.003)PIEK;AS(0.027)VS(0.973)PMDEPVPDSESPIEK;AS(0.011)VS(0.989)PMDEPVPDSESPIEK;AS(0.007)VS(0.993)PMDEPVPDSESPIEK;AS(0.215)VS(0.785)PMDEPVPDSESPIEK;AS(0.052)VS(0.948)PMDEPVPDSESPIEK;AS(0.212)VS(0.787)PMDEPVPDS(0.001)ESPIEK;AS(0.022)VS(0.978)PMDEPVPDSESPIEK;AS(0.028)VS(0.972)PMDEPVPDSESPIEK;AS(0.003)VS(0.997)PMDEPVPDSESPIEK;AS(0.015)VS(0.985)PMDEPVPDSESPIEK 238.05 9.7518e-44 347700600.0 587559.1 557086.4 715443.1 910966.2 837513.9 803655.9 648191.8 834133.1 695708.1 756025.1 True False 774390.6718115096 737153.6843816915 705955.8570317826 700957.0168774893 721239.551527224 753403.1695286811 705879.6144860969 705236.9958667711 732481.8098497642 729556.8913651302 1.06145343972077 1.0104128863786708 0.9676501797012899 0.9607982943809557 0.988599463679463 1.0326859747961947 0.9675456744233765 0.9666648402801702 1.0040091712096104 1.0 19.47666095935181 -4.850310357802054 3.0812453165972453 0.9850908054919945 1.0675992717689555 0.5412099062268017 0.021080124391316922 0.24598521966961678 3.7588912382376334 0.0056551270699578375 0.04589225743807955 1.411528470226871e-05 4.850310357802054 0.08250846627696107 ASVS(ph)PMDEPVPDSESPIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 ASVSPMDEPVPDSESPIEK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 AS(0.002)VS(0.998)PMDEPVPDSESPIEK;AS(0.041)VS(0.959)PMDEPVPDSESPIEK;AS(0.465)VS(0.535)PMDEPVPDSESPIEK;AS(0.065)VS(0.929)PMDEPVPDS(0.002)ES(0.004)PIEK;AS(0.001)VS(0.997)PMDEPVPDS(0.001)ESPIEK;AS(0.017)VS(0.983)PMDEPVPDSESPIEK;AS(0.052)VS(0.948)PMDEPVPDSESPIEK;AS(0.019)VS(0.981)PMDEPVPDSESPIEK 169.06 2.6366999999999996e-20 152763000.0 411176.8 450149.0 434617.9 533495.0 556182.0 483162.0 498642.0 469180.2 457859.0 390278.6 True False 480780.9111280207 494836.81778889865 444980.83903356537 503605.00476412574 447202.1296858949 457824.1341619107 451407.0199045479 456864.7168875147 464554.3216908722 461033.02073630143 1.042834004297958 1.073321856639705 0.9651821431855366 1.092340422731183 0.9700002159751645 0.9930397901450401 0.9791207995983018 0.9909587737508917 1.0076378497768923 1.0 18.814510559465482 -6.28855561209411 24.999311505518754 0.9892695814177437 1.039967107177268 0.39408336478754213 0.032249690996718094 774.3107267908011 713858.9626525698 0.009541160366434003 0.010820617274752975 5.145699113052012e-07 6.28855561209411 0.05069752575952435 ASVS(ph)PMDEPVPDSESPIEK ddPTM_PC-9_Lapatinib_30min_R1 15 ASVSPMDEPVPDSESPIEK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ASVS(1)PMDEPVPDSESPIEK;AS(0.16)VS(0.84)PMDEPVPDSESPIEK;ASVS(1)PMDEPVPDSESPIEK;AS(0.038)VS(0.962)PMDEPVPDSESPIEK;AS(0.029)VS(0.971)PMDEPVPDSESPIEK;AS(0.021)VS(0.978)PMDEPVPDSESPIEK;AS(0.03)VS(0.97)PMDEPVPDSESPIEK;AS(0.007)VS(0.993)PMDEPVPDSESPIEK;AS(0.027)VS(0.973)PMDEPVPDSESPIEK;AS(0.006)VS(0.994)PMDEPVPDSESPIEK;AS(0.022)VS(0.978)PMDEPVPDSESPIEK;AS(0.022)VS(0.978)PMDEPVPDSESPIEK;AS(0.255)VS(0.745)PMDEPVPDSESPIEK;AS(0.039)VS(0.961)PMDEPVPDSESPIEK;AS(0.092)VS(0.908)PMDEPVPDSESPIEK 237.34 3.2143999999999996e-47 250776500.0 556041.0 524486.0 578678.0 515463.2 562983.0 548831.0 492935.0 512872.0 577324.0 467847.8 True False 548111.7533745678 523271.5848913245 531101.3286016777 553372.0832628269 529869.4468071639 525358.7775175489 518456.76235052064 536701.9054512858 512299.69162876386 548714.6688619914 0.9989012222168692 0.9536314856983237 0.9679007300882935 1.0084878620258044 0.9656556984454022 0.9574352706974619 0.9448567566560154 0.9781074498416098 0.9336358597652392 1.0 19.065696618517926 -6.504891014437355 24.740894134517085 0.9604533956440067 0.9801524798328044 0.14502042136295734 0.022034113844361124 1250.2750745956928 1719671.9648646484 0.006650159422709009 0.0073985992144247024 3.126863950592648e-07 6.504891014437355 0.019699084188797733 ASVS(ph)QTSPQSASSPR ddPTM_PC-9_AZD4547_30min_R2 2 ASVSQTSPQSASSPR 15 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 AS(0.001)VS(0.998)QT(0.001)SPQSASSPR;AS(0.006)VS(0.993)QTSPQSASSPR 147.49 1.255e-09 3207700.0 7375.200000000001 7446.7 15491.0 20398.9 14545.3 15211.6 10265.3 17980.300000000003 10866.0 10073.5 True False 9720.360186310165 9853.700146844616 15285.579218360415 15696.248764863314 12525.93616515373 14260.416247304976 11178.891813478873 15201.857781190167 11440.354576621341 9720.829831134768 0.999951686755888 1.0136686186280393 1.5724562083580926 1.6147025549804324 1.2885665506698316 1.4669957704259367 1.1499935712971838 1.5638436270636338 1.1768907362187455 1.0 13.246863761266958 -5.238764864020493 23.266999504155933 1.3780160230974574 1.006809787221034 0.3317668402221794 0.19486247292996717 337.1703438650251 345976.5322866567 0.0472346340828083 0.12469673739993663 5.770788211884777e-06 5.238764864020493 -0.37120623587642343 ASVS(ph)QTSPQSASSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASVSQTSPQSASSPR 15 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 ASVS(0.376)QT(0.368)S(0.17)PQS(0.017)AS(0.035)S(0.035)PR;AS(0.005)VS(0.995)QTSPQSASSPR 182.91 2.4729e-06 10919900.0 13790.6 13126.6 16812.4 16596.6 17902.1 15157.3 16592.0 15205.1 13063.4 13282.1 True False 16125.076203234405 14429.72209732281 17213.27137738207 15666.74630890319 14394.312016300131 14362.424505098326 15020.285644322526 14805.982236135142 13254.427511475247 15690.039588954249 1.0277269290376054 0.9196740400503068 1.0970827243482657 0.998515409733736 0.9174171890830469 0.91538484805414 0.9573134318218529 0.943654867930258 0.84476698967709 1.0 13.937561372054052 -6.208714189884818 5.652657998334843 0.9275936681678615 1.0113231686285395 0.3477764069537307 0.054415156385647465 0.24299275835410553 17.828719407170805 0.015870191092578624 0.020422707387079575 6.184232518960769e-07 6.208714189884818 0.08372950046067806 ASVS(ph)QTSPQSASSPR ddPTM_PC-9_Lapatinib_30min_R1 2 ASVSQTSPQSASSPR 15 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 AS(0.241)VS(0.754)QT(0.002)S(0.001)PQS(0.001)AS(0.001)SPR;AS(0.016)VS(0.937)QT(0.027)S(0.014)PQS(0.005)AS(0.001)SPR 81.992 0.0082535 5999100.0 9871.3 10537.400000000001 11984.2 9646.0 10356.7 11443.9 7183.0 9412.5 9716.0 8979.7 True False 9730.533451825288 10513.001297715926 10998.905336349799 10355.399018112703 9747.53926805562 10954.471074033861 7554.900593311072 9849.839112020623 8621.681765984213 10531.829180301867 0.9239167560773509 0.9982122875083128 1.0443490060512493 0.9832479088704601 0.9255314628808129 1.0401299609494692 0.717339833752842 0.9352448604505664 0.8186309916713912 1.0 13.362468406622408 -7.228697154185339 24.99915464057276 0.8624075535301934 0.9862501290812097 0.3527448949908182 0.07823096614378731 660.8582460152229 504575.34866633883 0.028108925504820158 0.021771659353063248 5.906127875940626e-08 7.228697154185339 0.1238425755510163 ASVSGPNS(ph)PSETR ddPTM_PC-9_AZD4547_30min_R2 1 ASVSGPNSPSETR 13 0 C9J453;A0A087X255;O15344-2;O15344;A0A087X0X0 C9J453 MID1 E3 ubiquitin-protein ligase Midline-1 1 ASVS(0.002)GPNS(0.373)PS(0.373)ET(0.251)R 102.15 0.0018216999999999999 5444300.0 14550.0 19123.0 23096.0 28118.0 23125.0 29294.0 26480.0 32522.0 22038.0 27669.0 True False 19176.59734119927 25304.135779353204 22789.73194934169 21635.829518769493 19914.492916555864 27462.24154911727 28836.668701442766 27496.47218121314 23202.8836885313 26700.316731788153 0.7182160996003657 0.9477091988660674 0.8535378878936405 0.8103210810608431 0.7458523101655419 1.0285361714987449 1.0800122332298467 1.0298182024364197 0.8690115522452596 1.0 14.704569235494855 -6.772831129224917 24.998831363664085 1.0082478447709946 0.8243598821056101 0.5928324767780702 0.07692546218202274 162.68397273038985 357002.7212923731 0.027549576964554446 0.02450512216038433 1.687208951052627e-07 6.772831129224917 -0.18388796266538454 ASVSGPNS(ph)PSETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASVSGPNSPSETR 13 0 C9J453;A0A087X255;O15344-2;O15344;A0A087X0X0 C9J453 MID1 E3 ubiquitin-protein ligase Midline-1 1 ASVS(0.008)GPNS(0.581)PS(0.277)ET(0.133)R 133.48 4.3376000000000006e-05 5185400.0 15185.0 21195.0 22155.0 22442.0 26210.0 17890.0 22121.0 17408.0 16134.0 13734.0 True False 17755.520582579036 23299.099527124843 22683.25922330538 21184.647497945687 21074.3386500593 16951.816906454915 20025.538737828978 16951.058445300623 16369.929227470771 16223.865481715819 1.0944075320760878 1.436100388861259 1.398141475523774 1.3057706575427808 1.2989714857910977 1.0448691728589277 1.2343259847905925 1.0448224231398089 1.0090030175558078 1.0 13.98582997511564 -7.126226722452755 0.8373316874936886 1.0110695920420356 1.3316695282692554 0.5513900042913626 0.10614647039660076 0.46398241612287183 0.6563640733053145 0.0803360921827187 0.053410550867805266 7.477790222473201e-08 7.126226722452755 0.32059993622721983 ASVSGPNS(ph)PSETRR ddPTM_PC-9_AZD4547_30min_R2 3 ASVSGPNSPSETRR 14 1 C9J453;A0A087X255;O15344-2;O15344;A0A087X0X0 C9J453 MID1 E3 ubiquitin-protein ligase Midline-1 1 ASVSGPNS(0.977)PS(0.023)ETRR;ASVS(0.205)GPNS(0.612)PS(0.144)ET(0.04)RR;ASVSGPNS(0.991)PS(0.005)ET(0.003)RR 138.81 6.3380999999999995e-06 33253200.0 55315.0 51053.0 84734.0 126785.0 105593.0 91501.0 76286.0 111822.0 85958.0 102617.0 True False 72904.01937652504 67554.88385417128 83610.37179578799 97556.67705872361 90933.23461785448 85779.42800524962 83075.30621443587 94542.47931392975 90501.56439326506 99024.41006418367 0.7362227084137292 0.6822043555764169 0.8443410240121105 0.9851780686751 0.9182911017487021 0.8662452818416269 0.8389376534592812 0.95473913202463 0.9139318712891655 1.0 16.59549658087993 -5.430028550683695 3.9654133081330922 0.9172462260937067 0.711328799904306 0.7547444309526836 0.04858558158949991 0.1113020532040171 3.1251877385281888 0.013365236875070331 0.02936009371104754 3.7151080503335438e-06 5.430028550683695 -0.20591742618940068 ASVSGPNS(ph)PSETRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASVSGPNSPSETRR 14 1 C9J453;A0A087X255;O15344-2;O15344;A0A087X0X0 C9J453 MID1 E3 ubiquitin-protein ligase Midline-1 1 ASVS(0.001)GPNS(0.999)PSETRR;ASVSGPNS(0.487)PS(0.487)ET(0.026)RR;ASVSGPNS(0.917)PS(0.064)ET(0.019)RR 137.27 0.00010074 34487100.0 68127.0 62169.0 101838.0 100189.0 136819.0 121093.0 110502.0 108818.0 105690.0 85896.0 True False 79659.5555304158 68340.72745939252 104266.20414276584 94575.73514712071 110010.29911340961 114742.66990795686 100034.45059480051 105961.64280220139 107235.51630416418 101468.26484763833 0.7850686680217719 0.6735182429896766 1.0275745258808635 0.9320720649863556 1.0841842942578916 1.1308232192622094 0.9858693330866474 1.0442835793172394 1.0568379824488552 1.0 16.63066905597634 -5.268730099833612 24.783966204678947 1.0343631367742772 0.7292934495503205 0.8185145807347496 0.057143683734883946 171.0328061635707 581408.247826644 0.015283800044438156 0.03288081657138549 5.3860440398267964e-06 5.268730099833612 -0.30506968722395666 ASVSGPNS(ph)PSETRR ddPTM_PC-9_Lapatinib_30min_R1 3 ASVSGPNSPSETRR 14 1 C9J453;A0A087X255;O15344-2;O15344;A0A087X0X0 C9J453 MID1 E3 ubiquitin-protein ligase Midline-1 1 ASVSGPNS(0.999)PS(0.001)ETRR;ASVSGPNS(0.953)PS(0.036)ET(0.011)RR;ASVSGPNS(0.998)PS(0.002)ETRR 158.65 1.5808e-05 25542400.0 63458.0 50318.7 63179.0 50186.0 57514.0 49532.3 49980.0 45601.2 69587.0 42860.8 True False 62553.07728322802 50202.19014172169 57984.66649799263 53876.84585558827 54131.139596874586 47413.91899443082 52567.71984598182 47719.99822736515 61749.37927640419 50269.23217157391 1.2443611048151306 0.9986663406828375 1.1534822393961612 1.0717658402201413 1.0768244760954295 0.9431995864309679 1.0457235484831544 0.9492883850800033 1.2283732336640312 1.0 15.617388032562786 -4.751714902090559 24.996042904116745 1.0513204697420933 1.2443614914054075 0.32131034803089986 0.08389960292474696 478.38177090980207 1229559.3383032463 0.020063292458399506 0.26022278093920165 1.7712713494230924e-05 4.751714902090559 0.19304102166331427 ASVSGPNSPSET(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 ASVSGPNSPSETR 13 0 C9J453;A0A087X255;O15344-2;O15344;A0A087X0X0 C9J453 MID1 E3 ubiquitin-protein ligase Midline-1 1 ASVS(0.01)GPNS(0.302)PS(0.155)ET(0.533)R 103.77 0.0034593000000000002 5963200.0 21492.0 27983.0 23324.0 23087.0 35193.0 31413.0 30126.0 32166.0 27806.0 19362.0 True False 21185.520138849908 27918.207082770383 21406.390753243657 24784.894995974286 33123.01693210016 30069.53921727954 31685.776872349907 33660.5497877562 24674.195469839146 22708.69590175671 0.9329254410074261 1.2294060039181147 0.9426516980919055 1.0914274911778163 1.4586049800216758 1.3241420532190669 1.3953146851510194 1.4822757737115266 1.0865527274919555 1.0 14.470957237946092 -6.1322515395896176 6.281105211147482 1.3213870269018553 1.048950792532445 0.3390587168657947 0.16317961262132777 0.24305150417560004 11.383482437567725 0.04587608207423503 0.05963020279029634 7.374769661576105e-07 6.1322515395896176 -0.2724362343694102 ASVSGPNSPSET(ph)RR ddPTM_PC-9_Lapatinib_30min_R1 1 ASVSGPNSPSETRR 14 1 C9J453;A0A087X255;O15344-2;O15344;A0A087X0X0 C9J453 MID1 E3 ubiquitin-protein ligase Midline-1 1 ASVSGPNS(0.327)PS(0.065)ET(0.607)RR 175.26 0.00040432 4683500.0 16615.0 15463.0 18308.0 16789.0 14359.0 14168.0 12831.0 14469.0 20072.0 10636.0 True False 16378.067053182165 15427.19637354389 16802.786910923718 18023.71906646218 13514.43185088017 13562.067667221107 13495.32639743483 15141.282561681413 17811.279992469656 12474.418428420842 1.3129323140121325 1.2367066618829816 1.3469795812397494 1.4448544571343063 1.0833716961176991 1.08719037645252 1.081840125443285 1.2137866505411246 1.4278244789263828 1.0 13.606684936595661 -6.2707077976935235 24.99363893572206 1.1532428558361922 1.3291503798037227 0.37346649202068005 0.1180683913582882 804.9340966817743 2170617.8229052396 0.03819880528223668 0.04387490032587082 5.361572738836002e-07 6.2707077976935235 0.1759075239675305 ASVSPMDEPVPDS(ph)ESPIEK ddPTM_PC-9_AZD4547_30min_R2 9 ASVSPMDEPVPDSESPIEK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ASVSPMDEPVPDS(0.67)ES(0.33)PIEK;ASVSPMDEPVPDS(0.844)ES(0.156)PIEK;ASVSPMDEPVPDS(0.801)ES(0.199)PIEK;ASVSPMDEPVPDS(0.998)ES(0.002)PIEK;ASVSPMDEPVPDS(0.771)ES(0.229)PIEK;ASVSPMDEPVPDS(0.756)ES(0.244)PIEK;ASVSPMDEPVPDS(0.865)ES(0.135)PIEK;ASVSPMDEPVPDS(0.798)ES(0.202)PIEK;ASVSPMDEPVPDS(0.85)ES(0.15)PIEK 206.21 1.6623000000000003e-20 347049300.0 375046.1 368866.0 430763.0 476004.5 461326.0 458299.0 425504.0 463968.0 424369.0 439376.0 True False 494302.9583565055 488094.72093222255 425050.80116445624 366269.0167212143 397278.8479664017 429641.4910807302 463373.03168952913 392272.4065239867 446800.27897351515 423993.57997564663 1.1658265164885215 1.151184225384398 1.0024934839552766 0.8638551006886757 0.9369926025512477 1.0133207467561371 1.0928774716733787 0.9251847788509394 1.0537901988968288 1.0 18.693682894396467 -5.274126914111072 4.624383434760797 0.981080828722896 1.1618656125986666 0.5564307284899153 0.06174059600565091 0.13633132043936066 8.073190600777115 0.017156617749819664 0.04179204990834842 5.319527837011806e-06 5.274126914111072 0.18078478387577057 ASVSPMDEPVPDS(ph)ESPIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASVSPMDEPVPDSESPIEK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ASVSPMDEPVPDS(0.824)ES(0.176)PIEK;ASVSPMDEPVPDS(0.984)ES(0.016)PIEK;ASVSPMDEPVPDS(0.999)ES(0.001)PIEK 172.93 1.6748000000000002e-08 42490800.0 84830.0 83929.0 86760.0 102636.0 108523.0 93860.0 103777.0 94609.0 89920.0 77264.0 True False 99190.04353112805 92260.91645256229 88828.68743913219 96885.63767040177 87258.69718887392 88937.81636891337 93946.49127958405 92125.61399652153 91234.90988807313 91271.35157851258 1.0867598848451776 1.0108420096441595 0.9732373401167487 1.0615120297310348 0.9560359924528242 0.9744329938229097 1.0293097412803216 1.009359589873873 0.9996007324334614 1.0 16.477874475011454 -4.77028566758514 4.496164446278936 1.0009187749730575 1.093266877178597 0.4514204791098948 0.028355053899342522 0.17902926024289903 7.983542744635639 0.007010369847326624 0.052949115629816246 1.69712695937815e-05 4.77028566758514 0.09234810220553946 ASVSPMDEPVPDS(ph)ESPIEK ddPTM_PC-9_Lapatinib_30min_R1 7 ASVSPMDEPVPDSESPIEK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ASVSPMDEPVPDS(0.902)ES(0.098)PIEK;ASVSPMDEPVPDS(0.986)ES(0.014)PIEK;ASVSPMDEPVPDS(0.954)ES(0.046)PIEK;ASVSPMDEPVPDS(0.712)ES(0.288)PIEK;ASVSPMDEPVPDS(0.84)ES(0.159)PIEK;ASVSPMDEPVPDS(0.543)ES(0.457)PIEK;ASVSPMDEPVPDS(0.574)ES(0.426)PIEK 210.39 6.2574e-21 179052500.0 379424.0 359971.0 384099.0 371861.0 373061.0 367025.0 334998.0 361489.0 389376.0 310763.0 True False 374013.34418216074 359137.50926605286 352519.8628850173 399208.89843193133 351118.2854461455 351328.1963270631 352342.5572821969 378285.0986204742 345520.37456894526 364477.97048433195 1.0261617284719782 0.9853476433399185 0.9671911375509903 1.0952895120148074 0.9633456995482235 0.9639216215460293 0.9667046730258921 1.0378819277274696 0.9479869911199431 1.0 18.47547209328681 ASVSPMDEPVPDSES(ph)PIEK ddPTM_PC-9_AZD4547_30min_R2 6 ASVSPMDEPVPDSESPIEK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ASVSPMDEPVPDS(0.018)ES(0.982)PIEK;ASVSPMDEPVPDS(0.324)ES(0.676)PIEK;ASVSPMDEPVPDS(0.302)ES(0.698)PIEK;ASVSPMDEPVPDS(0.347)ES(0.653)PIEK;ASVSPMDEPVPDS(0.071)ES(0.929)PIEK;ASVSPMDEPVPDS(0.086)ES(0.914)PIEK 225.86 3.0999e-35 62248000.0 146864.0 133107.0 154330.0 192747.0 177552.0 165657.0 160569.0 183619.0 146912.0 160448.0 True False 193563.69703903052 176131.23470074605 152283.48336256936 148312.1570614647 152901.9695706083 155298.44160244826 174859.32993663047 155244.90269485835 154677.4683932077 154830.76435657032 1.250163026989 1.137572596975117 0.9835479660351307 0.9578985008425491 0.9875425611054914 1.0030205705424338 1.1293577905094818 1.0026747806872172 0.9990099127650782 1.0 17.240332633095704 -5.006409881812997 2.8953631536001407 1.0099248485519408 1.2490235476794354 0.7616388381431947 0.0437050165193412 0.1465604220341775 2.2873805435712646 0.01261253629301285 0.06443434913362428 9.853490862509641e-06 5.006409881812997 0.2390986991274946 ASVSPMDEPVPDSES(ph)PIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ASVSPMDEPVPDSESPIEK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ASVSPMDEPVPDS(0.262)ES(0.738)PIEK;ASVSPMDEPVPDS(0.013)ES(0.987)PIEK;ASVSPMDEPVPDS(0.041)ES(0.959)PIEK 187.75 4.533e-11 267587000.0 93983.8 103136.3 93545.0 111243.0 116435.0 103649.0 112323.0 100616.0 91767.1 85656.8 True False 109893.4010753368 113374.99025993899 95775.46757138803 105010.41536467188 93620.39758564132 98213.46397636375 101682.95229190197 97974.93661146417 93109.02023120319 101185.69978114418 1.0860566395550617 1.1204645568015952 0.9465316519878005 1.0377989734893391 0.925233484456144 0.9706259302331346 1.004914256775743 0.9682686073563299 0.9201796344008082 1.0 16.626645887862303 -5.25913186054342 24.992361296771726 0.9724106725191191 1.1032606090912584 0.6919315467272558 0.03511278062961558 102.19929625049329 1106883.3716737388 0.008789634987007711 0.021065663522301773 5.506404854912085e-06 5.25913186054342 0.1308499365721394 ASVSPMDEPVPDSES(ph)PIEK ddPTM_PC-9_Lapatinib_30min_R1 5 ASVSPMDEPVPDSESPIEK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ASVSPMDEPVPDS(0.001)ES(0.999)PIEK;ASVSPMDEPVPDS(0.012)ES(0.988)PIEK;ASVS(0.002)PMDEPVPDS(0.021)ES(0.977)PIEK;ASVSPMDEPVPDS(0.012)ES(0.988)PIEK;ASVSPMDEPVPDS(0.002)ES(0.998)PIEK 242.94 1.5089e-53 174347500.0 329352.0 309761.0 315354.0 304467.0 312458.0 316629.0 265159.0 286356.0 326439.0 253010.0 True False 324655.3800842409 309043.7674361589 289426.81142164354 326858.51885213854 294079.8347560636 303087.5157682493 278887.63558704837 299661.1451539733 289672.00226493663 296742.44138536695 1.094064531411685 1.0414545556522423 0.9753468700682997 1.101488945518451 0.9910272133070256 1.0213824296695135 0.9398306298385835 1.0098358150420956 0.976173145009452 1.0 18.17885175648688 -6.4157677894441525 13.591673525863273 0.989094883810832 1.0467059253074262 0.3945069831528686 0.0381434847729347 1.1419951027647348 140.5902614938972 0.011655185331776756 0.013215131179710191 3.839124626920106e-07 6.4157677894441525 0.05761104149659424 ASVSQT(ph)SPQSASSPR ddPTM_PC-9_AZD4547_30min_R2 1 ASVSQTSPQSASSPR 15 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 ASVS(0.21)QT(0.566)S(0.22)PQS(0.001)AS(0.003)SPR 226.74 5.3878e-24 12656000.0 12345.0 14209.0 19515.0 27548.0 22134.0 20629.0 15453.0 23699.0 13955.0 18578.0 True False 16270.453208048451 18801.781377860672 19256.218349125513 21197.234212357274 19061.076160650704 19339.06536890626 16828.287063572334 20036.86409884295 14692.632810302863 17927.589874703117 0.9075650057684004 1.0487623550776946 1.074110824918924 1.1823805854833738 1.0632258041303702 1.0787320272311014 0.9386809482583064 1.1176552028957414 0.8195542687550562 1.0 14.129893929689564 -8.254968964413084 24.993876676689727 0.9097771322514235 1.0539743601128466 0.3059019119292068 0.08525444023861019 558.4543929115961 2157215.4664064106 0.060257507611832364 0.021557061720440984 5.5594398476427685e-09 8.254968964413084 0.14419722786142308 ASVSQT(ph)SPQSASSPR ddPTM_PC-9_Lapatinib_30min_R1 2 ASVSQTSPQSASSPR 15 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 ASVSQT(0.562)S(0.247)PQS(0.089)AS(0.089)S(0.012)PR;ASVSQT(0.492)S(0.492)PQS(0.014)AS(0.001)SPR 160.93 6.4386e-05 24193000.0 25282.0 21932.7 25352.0 19660.2 19410.5 23748.0 21815.0 23278.4 27208.0 19686.5 True False 24921.474043849023 21881.916180691085 23267.656421550026 21106.076692504597 18268.8125525113 22732.353399291835 22944.473958385228 24359.99944597725 24143.54852705831 23089.285294387642 1.0793523370732803 0.9477086839933484 1.0077252771096272 0.9141069731437245 0.7912246879703952 0.9845412324138691 0.9937282018842907 1.0550347979761194 1.045660280048899 1.0 14.494935896178115 -7.372046474942492 2.7119372667729604 1.0354779707401796 0.9464130228358375 0.2005098774402162 0.0705038184384923 0.4524129946679457 6.454093482904274 0.03642252058767676 0.022577129215478345 4.2457412677229007e-08 7.372046474942492 -0.08906494790434205 ASVSQTS(ph)PQSASSPR ddPTM_PC-9_AZD4547_30min_R2 2 ASVSQTSPQSASSPR 15 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 ASVSQT(0.358)S(0.474)PQS(0.044)AS(0.123)SPR;ASVSQT(0.311)S(0.367)PQS(0.011)AS(0.311)SPR 233.48 8.584199999999998e-32 15898400.0 16204.3 17053.300000000003 27020.0 37034.0 26784.0 23682.0 20426.4 28971.0 21890.9 25825.0 True False 21356.930329621682 22565.445729542644 26661.697145445632 28496.383469596316 23065.503925493267 22201.16079627893 22244.310028819906 24494.1976373509 23048.008282841918 24920.874610518214 0.8569895986157597 0.9054836991964388 1.0698539903648758 1.1434744532428651 0.9255495357196709 0.890866036736472 0.8925974861023286 0.9828787319933294 0.9248474880217155 1.0 14.605067080901549 ASVSQTS(ph)PQSASSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASVSQTSPQSASSPR 15 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 ASVS(0.001)QT(0.194)S(0.689)PQS(0.033)AS(0.063)S(0.02)PR;ASVS(0.002)QT(0.223)S(0.766)PQS(0.006)AS(0.002)S(0.001)PR 241.66 9.486399999999999e-33 15703700.0 24538.0 26716.0 30285.0 35892.0 43303.0 31761.0 35237.0 27682.0 31334.0 27658.0 True False 28691.79875240858 29368.18792010698 31007.1092565021 33881.08760343401 34818.08800318647 30095.397247955007 31899.0962662122 26955.376831503447 31792.20047189594 32672.176459392467 0.8781722511834799 0.8988745502341436 0.9490371507707837 1.0370012431080027 1.0656800916358025 0.9211323061186303 0.9763382707564305 0.8250254422139797 0.9730665023620256 1.0 14.99577494276085 -5.267188718467754 3.5539812336775456 0.9674755679061349 0.884719849030399 0.21625714439606658 0.061871518007100876 0.3938805599810889 10.811935982954855 0.017882560815724584 0.04828469747396749 5.405193944299567e-06 5.267188718467754 -0.08275571887573585 ASVSQTSPQS(ph)ASSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASVSQTSPQSASSPR 15 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 ASVS(0.127)QT(0.113)S(0.16)PQS(0.374)AS(0.113)S(0.113)PR 163.34 0.00033508 5160900.0 10300.0 8768.5 10409.0 11044.0 13935.0 12377.0 11570.0 10261.0 10872.0 8736.7 True False 12043.586565726971 9638.978731002317 10657.190036352327 10425.24048513109 11204.536783234496 11727.92833153675 10474.005840453934 9991.659622428173 11030.982432196739 10320.59455032086 1.166946972580426 0.9339557603978006 1.032613962731537 1.0101395258092931 1.0856483828139682 1.1363616964462708 1.0148645787202544 0.9681282966510432 1.0688320695491127 1.0 13.33323846369164 -7.488430075768725 24.983432352659637 1.009387332149511 1.0546076166118588 0.10997492435386291 0.06527595175403599 1530.1047660371037 1109690.4451116289 0.027498901635208645 0.018529124618094167 3.247655273170273e-08 7.488430075768725 0.045220284462347715 ASVVDPSTESSPAPQEGSEQPASPAS(ph)PLSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ASVVDPSTESSPAPQEGSEQPASPASPLSSR 31 0 Q66K14;Q66K14-2 Q66K14 TBC1D9B TBC1 domain family member 9B 1 ASVVDPSTESSPAPQEGS(0.003)EQPAS(0.063)PAS(0.532)PLS(0.104)S(0.298)R 69.89399999999999 3.2304e-05 4319600.0 7090.5 9570.8 11386.0 11506.0 11465.0 10474.0 10002.0 9594.1 12717.0 8705.3 True False 8290.781606241462 10520.925772786339 11657.485421645464 10861.356122955303 9218.515552191146 9924.725001576795 9054.53815179086 9342.265040789214 12902.962066799671 10283.501978883118 0.8062216182061664 1.0230878347075505 1.133610461259577 1.056192350160363 0.8964373781539702 0.9651114009563025 0.8804917012107452 0.9084711667264024 1.2547245182910978 1.0 13.328044028050956 -8.245097910781666 24.749184395198494 1.1273622945791306 0.9654600938268846 0.2857358109602085 0.10623496172581903 850.4160436241524 1287962.9935236298 0.07442415706054936 0.027938156296648014 5.687246985969741e-09 8.245097910781666 -0.16190220075224604 ASWES(ph)LDEEWRAPQAGSR ddPTM_PC-9_AZD4547_30min_R2 1 ASWESLDEEWRAPQAGSR 18 1 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 AS(0.367)WES(0.633)LDEEWRAPQAGSR 72.383 0.003817 4417100.0 3552.1 1658.2 4722.7 9223.7 8413.0 6662.4 4803.1 6738.7 5284.7 5320.2 True False 4681.593911730167 2194.1807221316476 4660.073912242636 7097.318469744435 7245.000168950678 6245.799074787971 5230.566595162381 5697.388754921009 5564.0384530711235 5133.941417342849 0.9118907932831846 0.4273871756151203 0.907699082132209 1.3824307472167774 1.4111965018682353 1.2165699931224736 1.018820857108561 1.1097494676652897 1.0837752129923754 1.0 12.32585111828653 -5.533139903885195 6.585361418059773 1.1826702159457734 0.6673071700466706 0.593295228369955 0.1691834276408246 0.09023870624594875 18.143995297344922 0.04713755806597892 0.08630577160060943 2.9299492376000456e-06 5.533139903885195 -0.5153630458991028 ASYDVSDSGQLEHVQPWS(ph)V ddPTM_PC-9_AZD4547_30min_R2 2 ASYDVSDSGQLEHVQPWSV 19 0 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 1 ASYDVSDSGQLEHVQPWS(1)V;ASYDVSDSGQLEHVQPWS(1)V 149.86 8.489399999999999e-05 7223800.0 31867.0 28577.0 52068.0 68354.0 51212.0 50568.0 39895.0 62755.0 40863.0 49461.0 True False 42000.04312522316 37813.956396306894 51377.54429937317 52596.04135877267 44102.09778346633 47405.97496605996 43445.57771314424 53057.656716439036 43022.93475653211 47729.385444756714 0.8799619507742279 0.7922573493026386 1.0764342306237933 1.101963515110597 0.9240030512127857 0.9932240803923387 0.9102480014838936 1.1116350278142468 0.9013930172289358 1.0 15.542590140169406 -5.255339240937723 24.99990405629273 1.0034920166044803 0.8361096398462341 0.4406983853985029 0.07490857457869456 431.9496895427795 1770226.2960721573 0.018855643821431768 0.04718169420108992 5.554701927046412e-06 5.255339240937723 -0.1673823767582462 ASYDVSDSGQLEHVQPWS(ph)V ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASYDVSDSGQLEHVQPWSV 19 0 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 1 ASYDVSDSGQLEHVQPWS(1)V;ASYDVSDSGQLEHVQPWS(1)V 120.9 0.00031701 0.0 9577.5 11803.8 11991.2 12186.1 14510.0 10654.7 12932.3 12981.8 10856.7 8241.4 True False 11198.781585752433 12975.603255403452 12277.115684879245 11503.352324869253 11666.86966090653 10095.94877547262 11707.258922256031 12641.041505354067 11015.458698641502 9735.500581113502 1.1503036225458854 1.3328131560667384 1.2610667096765809 1.1815881709447293 1.1983841574145464 1.037024104857882 1.2025328153097403 1.298448025351383 1.1314732721613792 1.0 13.24903944617807 -14.522878745279352 0.1729120727459854 0.21522611318459367 1.247504926276249 0.37737051466876814 0.07925197121335796 153.42150930918 1.451868205206938 41.441513109593295 0.2901677752866456 3.0000000000068113e-15 14.522878745279352 1.0322788130916554 ASYDVSDSGQLEHVQPWS(ph)V ddPTM_PC-9_Lapatinib_30min_R1 2 ASYDVSDSGQLEHVQPWSV 19 0 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 1 ASYDVSDSGQLEHVQPWS(1)V;ASYDVSDSGQLEHVQPWS(1)V 133.94 5.1908999999999994e-05 2854600.0 13395.599999999999 15639.7 20788.5 15520.400000000001 20953.9 20025.7 17379.0 14711.800000000001 23295.1 19876.7 True False 13204.576287547814 15603.4872355503 19079.349775930612 16661.82199053665 19721.432798952428 19169.247493186744 18278.799583899923 15395.363936066398 20671.36052972201 23312.361110962072 0.5664195155821725 0.6693224749428378 0.8184220244837839 0.7147204828901622 0.8459646238783982 0.8222782498068318 0.7840818652772482 0.6603948807582215 0.8867124368625966 1.0 14.50880750973778 -9.185566427582389 0.04300655378901826 1.7387019161256847 6.147045986136135e-17 0.5713575239463579 0.07849721309768616 119.41589923871209 1.944295386464709 43.752807424433286 34.269850629697224 6.522792638878851e-10 9.185566427582389 -1.7387019161256847 ASYDVSDSGQLEHVQPWSV ddPTM_PC-9_Lapatinib_30min_R1 1 ASYDVSDSGQLEHVQPWSV 19 0 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 0 78.615 0.014032 3416500.0 9959.1 9282.5 14377.0 10787.0 14790.0 16566.0 12740.0 9968.7 15050.0 10593.0 False True 9817.081407724741 9261.006941565105 13194.978556824904 11580.311964377128 13920.08127825877 15857.510797232144 13399.614862701255 10431.882194528544 13354.910516474114 12423.985935714742 0.7901716452772186 0.7454135081514263 1.0620567847629174 0.9320931321314251 1.1204199159822987 1.2763625843818114 1.0785278518532375 0.8396566326222589 1.074929622874353 1.0 13.60084048121875 -5.262708422634072 24.978454118125743 1.0499714234710817 0.7677925562660743 0.5125974646259905 0.10928256134461845 88.89390383922546 1749733.0555776726 0.030873770841245575 0.07053277050075378 5.461243959584196e-06 5.262708422634072 -0.2821788672050074 ASYNNPHR ddPTM_PC-9_AZD4547_30min_R2 2 ASYNNPHR 8 0 A0A494C0B4;P54725-2;P54725-3;P54725;K7ELU6 A0A494C0B4 RAD23A UV excision repair protein RAD23 homolog A 0 ; 104.44 0.0032381 1655480.0 8284.3 8148.5 13451.3 18362.0 15131.4 13766.3 9291.5 14923.5 12925.099999999999 13468.4 False True 10918.53507585548 10782.343272397622 13272.926973076706 14128.924590072029 13030.666296976144 12905.491084782312 10118.425499979436 12617.415982914159 13608.294398885377 12996.875415461907 0.8400892312059941 0.829610420022205 1.0212398402531728 1.087101640850028 1.0025999234765333 0.9929687461210193 0.7785275442389726 0.970803795495622 1.047043536533103 1.0 13.665877205538692 -5.253317494241132 23.93390886191141 0.9833163122922645 0.8348497842902544 0.3857703614556308 0.07691815828954951 389.8560917473881 1148830.1708436522 0.02160182530686077 0.05494278004361431 5.5806207010814075e-06 5.253317494241132 -0.1484665280020101 ASYNNPHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ASYNNPHR 8 0 A0A494C0B4;P54725-2;P54725-3;P54725;K7ELU6 A0A494C0B4 RAD23A UV excision repair protein RAD23 homolog A 0 ; 102.51 0.0035719000000000002 1977450.0 10453.7 10681.0 13645.4 16301.9 17203.9 15513.2 15612.900000000001 13597.1 15697.6 11219.3 False True 12223.304940013595 11741.339091730148 13970.758086467684 15388.557394472886 13832.919294229494 14699.660482572188 14133.933084392675 13240.190532318307 15927.147703058467 13253.270278070062 0.9222859478116332 0.8859201423786189 1.0541366616196484 1.1611139795387742 1.043736300852369 1.1091345889848365 1.0664487170219286 0.9990130929591471 1.2017522746376659 1.0 13.69406077181511 -5.322271663037528 4.878339848797706 1.083110658981098 0.9036783517221704 0.5682969015602757 0.06135964786371325 0.12855436237462636 6.292634585542956 0.015285727538088302 0.03399240415386514 4.761330594259715e-06 5.322271663037528 -0.17943230725892756 ASYNNPHR ddPTM_PC-9_Lapatinib_30min_R1 4 ASYNNPHR 8 0 A0A494C0B4;P54725-2;P54725-3;P54725;K7ELU6 A0A494C0B4 RAD23A UV excision repair protein RAD23 homolog A 0 ;;; 137.9 0.0026 4865880.0 29828.9 24891.999999999996 34285.4 26296.800000000003 29857.800000000003 26678.5 23343.6 28250.100000000002 33772.2 22185.4 False True 29403.53441604968 24834.364103359934 31466.58675747126 28230.754395553195 28101.62290669337 25537.522745620987 24552.217386887965 29562.70277806042 29968.419198967924 26020.116829812698 1.1300308376156256 0.9544293849943756 1.2093176584594825 1.0849587870876753 1.0799960311667691 0.9814530393023149 0.9435859780136391 1.1361479647235397 1.1517403782227233 1.0 14.667339819292053 -6.5433484636146275 24.484571838442022 1.0433313867242153 1.0915570191488564 0.08080413078727189 0.08379644365848854 598.4699059281479 715845.276972753 0.02877461438941447 0.02877742353973235 2.8618807693871643e-07 6.5433484636146275 0.04822563242464106 AT(ph)ISDEEIER ddPTM_PC-9_Lapatinib_30min_R1 1 ATISDEEIER 10 0 C9J0A7;Q9UQN3-2;Q9UQN3 C9J0A7 CHMP2B Charged multivesicular body protein 2b 1 AT(0.765)IS(0.235)DEEIER 158.08 0.0010049 283130000.0 18726.0 18384.0 22724.0 18552.0 21106.0 18341.0 10960.0 13634.0 17323.0 17140.0 True False 18458.963806072188 18341.43297750959 20855.720437176664 19916.375967657787 19864.586575992536 17556.598184959217 11527.455172308137 14267.48541336406 15371.901320722991 20102.626162385593 0.9182364362229999 0.9123898951982997 1.0374624822004699 0.990735031670822 0.9881587816203607 0.8733484890551118 0.5734303110047073 0.7097324149647782 0.7646713019757413 1.0 14.295096363737855 -7.019723067325141 6.796279341398804 0.7351898123072784 0.9678087074624845 0.4592149155344678 0.10448770711344917 0.13409288031408695 27.038121994433357 0.03786257712955332 0.030640859083244248 9.556017417923369e-08 7.019723067325141 0.23261889515520606 AT(ph)ISSPLELEGTVSR ddPTM_PC-9_AZD4547_30min_R2 2 ATISSPLELEGTVSR 15 0 Q96GS4 Q96GS4 C17orf59 Uncharacterized protein C17orf59 1 AT(0.998)IS(0.002)SPLELEGTVSR;AT(0.999)ISSPLELEGTVSR 116.79 0.00033945 1298200.0 4076.0 2910.24 8009.7 10931.1 9456.9 8856.2 5956.0 10203.900000000001 6431.299999999999 5609.6 True False 5372.083213933212 3850.9181671549895 7903.486144554996 8411.103778811474 8143.972672976309 8302.420413985534 6486.072461699141 8627.121717295395 6771.245388240827 5413.209611429352 0.9924025854440763 0.7113927676150267 1.4600369673229945 1.5538108409939313 1.5044628339869333 1.5337334058625691 1.1981934798912213 1.5937165446319033 1.250874411725004 1.0 12.40226853813394 -5.267480424443308 24.990488258253762 1.4167286775085386 0.8518976634940426 0.5547383597979012 0.1902079372642081 275.7135324616735 1140570.8194413746 0.04639790929270438 0.1007141806703663 5.401564614362422e-06 5.267480424443308 -0.564831014014496 AT(ph)ISSPLELEGTVSR ddPTM_PC-9_Lapatinib_30min_R1 1 ATISSPLELEGTVSR 15 0 Q96GS4 Q96GS4 C17orf59 Uncharacterized protein C17orf59 1 AT(1)ISSPLELEGTVSR 90.444 0.010313 1726800.0 1215.6 1425.1 3384.0 1407.6 1199.5 3021.0 3646.7 768.63 1285.2 3698.2 True False 1198.2653210862616 1421.8002685078836 3105.780582617755 1511.1195996159483 1128.947768307735 2891.7988722949567 3835.508282559861 804.3433558217696 1140.4472422440215 4337.42894245825 0.2762616603021838 0.32779793914089445 0.7160418358018207 0.3483906294864895 0.2602804064999623 0.6667080684567991 0.8842815256325735 0.18544242833541516 0.26293162547987925 1.0 12.082624407724095 -6.769575467976946 24.956406264226096 0.5667384144396641 0.39880820677712164 0.13759124314819826 0.2605105794227513 499.2362043669634 1531333.5574880647 0.09458393708163325 0.08484160719747104 1.6999045331188804e-07 6.769575467976946 -0.16793020766254246 AT(ph)LENIT(ph)NLRPVGEDFRWY(ph)LK ddPTM_PC-9_Lapatinib_30min_R1 1 ATLENITNLRPVGEDFRWYLK 21 2 Q9NWV4 Q9NWV4 C1orf123 UPF0587 protein C1orf123 3 AT(1)LENIT(1)NLRPVGEDFRWY(1)LK 49.176 0.026479000000000003 11992000.0 55456.0 47068.0 49124.0 42819.0 54175.0 52418.0 47753.0 51411.0 43013.0 33861.0 True False 54665.18727061513 46959.016937849294 45085.21434412372 45968.052099996654 50988.533012148044 50176.20433232608 50225.41668277653 53799.742745082825 38168.42299302997 39713.82873305358 1.376477388721718 1.1824348957512019 1.1352522731357697 1.1574822565958673 1.2838986982312937 1.2634441435903339 1.2646833177525947 1.354685369338505 0.9610864580594471 1.0 15.277353834542186 -8.273846912373445 24.985555980415263 0.9805431609596603 1.244742353519518 0.6777492212591394 0.0748090719544806 529.4474905945734 1066158.9270310055 0.0738631884696812 0.019613107818072822 5.322958590467484e-09 8.273846912373445 0.2641991925598576 AT(ph)NESEDEIPQLVPIGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ATNESEDEIPQLVPIGK 17 0 O76021;J3QSV6;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 AT(0.616)NES(0.384)EDEIPQLVPIGK;AT(0.588)NES(0.412)EDEIPQLVPIGK;AT(0.55)NES(0.45)EDEIPQLVPIGK;AT(0.547)NES(0.453)EDEIPQLVPIGK 138.04 7.6518e-08 13205200.0 102039.0 101286.8 103783.0 117449.0 129627.0 103563.2 116503.8 121882.0 101875.0 78163.8 True False 119312.1873378851 111341.88412285836 106257.58031921941 110868.71330479579 104227.51988520559 98132.16347940605 105467.71664953101 118682.72664465387 103364.72914643497 92334.27819569981 1.2921765315044365 1.2058564413843416 1.150792342731153 1.2007319001271963 1.1288063536306463 1.0627923388475273 1.142237950092546 1.285359337440309 1.1194621452214792 1.0 16.494578713253034 -14.522878745280336 0.11389082157948612 0.5019831643156911 1.2589232503112584 0.42382681073482387 0.06573640067058932 192.23856529406766 1.4363885677845083 22.85651680617418 0.8104664432107386 3.0000000000000132e-15 14.522878745280336 0.7569400859955673 AT(ph)NESEDEIPQLVPIGKK ddPTM_PC-9_Lapatinib_30min_R1 1 ATNESEDEIPQLVPIGKK 18 1 O76021;J3QSV6;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 AT(0.524)NES(0.476)EDEIPQLVPIGKK 60.761 0.021474 14004000.0 333390.0 66569.0 95569.0 66821.0 61587.0 60586.0 32086.0 40480.0 82211.0 42941.0 True False 328635.797463761 66414.86357048705 87711.68572700815 71735.23924832139 57964.573744700705 57994.87801286408 33747.25608199625 42360.8485795054 72951.53145979099 50363.2946347141 6.525303792124055 1.3187156251828893 1.741579584163082 1.4243555702346005 1.1509289486543488 1.151530662032776 0.670076418287678 0.8411055886384998 1.4485059404653684 1.0 15.620085043021207 -4.760937018566825 6.4890613469376035 1.1848375466297847 6.6778854083312496 0.9676182755923812 0.2926774929248449 0.02136790958088694 4.209661481376426 0.08203578515338632 0.518465536551313 1.7340554524317144e-05 4.760937018566825 5.493047861701465 AT(ph)PAQTPR ddPTM_PC-9_AZD4547_30min_R2 3 ATPAQTPR 8 0 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;E5RFR3;E5RG53 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 AT(0.999)PAQT(0.001)PR;AT(0.995)PAQT(0.005)PR;AT(1)PAQTPR 120.27 0.0083696 82037000.0 77119.0 83783.0 107568.0 135083.0 116750.0 91491.0 73257.0 140354.0 96068.0 104171.0 True False 101641.23782515113 110864.21628413693 106141.57803631727 103941.70136154568 100541.27775169276 85770.05330683042 79776.73108238651 118665.51431406391 101145.95835329079 100524.00499718467 1.0111140898932325 1.1028631050587554 1.0558829011964845 1.0339988081897127 1.0001718271621647 0.853229567497162 0.7936087612567841 1.1804694243667204 1.0061871127809077 1.0 16.617180530617546 -6.281211502379081 3.154249334746204 0.9645361778842274 1.0575450992632793 0.1379190498177988 0.09808086018291912 0.5398378684113371 11.03873978555913 0.03407848877405365 0.04178159031361754 5.233455040893995e-07 6.281211502379081 0.09300892137905192 AT(ph)PAQTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATPAQTPR 8 0 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;E5RFR3;E5RG53 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 AT(0.996)PAQT(0.004)PR;AT(0.992)PAQT(0.008)PR 99.788 0.012451 53579000.0 64080.0 54515.0 90703.0 66570.0 87575.0 72806.0 55723.0 40127.0 59360.0 56664.0 True False 74927.47836230912 59926.88892291629 92865.70351304299 62840.29872285193 70415.30741239776 68987.925192362 50444.51404041613 39073.708768070894 60228.027701913066 66936.73464802274 1.1193775548852893 0.8952765508809666 1.3873653084717088 0.9388013779472313 1.0519680677981469 1.0306437198516651 0.7536148021810655 0.5837408856815979 0.8997754076085955 1.0 16.030510553788595 -7.204449437939719 4.572992735869752 0.7740120458966404 1.0736787065155842 0.3853951298244016 0.15973620906463348 0.20194968680709915 8.903854980684589 0.06176270623324011 0.04635642642983697 6.245260555237951e-08 7.204449437939719 0.29966666061894376 AT(ph)PAQTPR ddPTM_PC-9_Lapatinib_30min_R1 3 ATPAQTPR 8 0 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;E5RFR3;E5RG53 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 AT(0.994)PAQT(0.006)PR;AT(0.998)PAQT(0.002)PR;AT(0.998)PAQT(0.002)PR 89.029 0.025751999999999997 54641000.0 84749.0 111855.0 153157.0 103377.0 120880.0 126126.0 103171.0 100471.0 129588.0 89909.0 True False 83540.46371893672 111596.00661985061 140565.02266311686 110979.68943556254 113770.07605922373 120731.88499406622 108512.68956042004 105139.24944741822 114992.43481786354 105449.6508537882 0.7922308233601476 1.0582871134830467 1.3330060509922226 1.0524424551148306 1.0789042461313814 1.1449244641072134 1.0290474049162943 0.9970564017627676 1.0904961172162337 1.0 16.686194792779965 -7.423411736112271 24.94873618650994 1.028873150124033 1.0865003070021955 0.029563947216119768 0.12586896727999156 161.4525656025562 40467.38999712046 0.054664948642746944 0.03685505706085937 3.772144004325676e-08 7.423411736112271 0.057627156878162555 AT(ph)PPPS(ph)PLLSELLK ddPTM_PC-9_AZD4547_30min_R2 3 ATPPPSPLLSELLK 14 0 Q9H0E9-3;H7C128;H7C179;H7C127;Q9H0E9-4;Q9H0E9-2 Q9H0E9-3 BRD8 Bromodomain-containing protein 8 2 AT(1)PPPS(0.997)PLLS(0.003)ELLK;AT(1)PPPS(1)PLLSELLK;AT(1)PPPS(0.918)PLLS(0.082)ELLK 154.6 0.00066237 5818000.0 44042.0 47997.0 57131.0 67660.0 58318.0 65731.0 61768.0 71201.0 52370.0 52589.0 True False 58046.439869491296 63511.09161750858 56373.40561126773 52062.03233657953 50221.55234195477 61620.830179047756 67265.2323395286 60198.52148621113 55138.17128452599 50747.87511684583 1.1438201054889625 1.251502481064985 1.1108525328689967 1.0258958077891513 0.9896286736404387 1.2142543906945304 1.3254787946224726 1.186227430165409 1.086511921091703 1.0 15.63105979549125 AT(ph)PPPS(ph)PLLSELLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATPPPSPLLSELLK 14 0 Q9H0E9-3;H7C128;H7C179;H7C127;Q9H0E9-4;Q9H0E9-2 Q9H0E9-3 BRD8 Bromodomain-containing protein 8 2 AT(1)PPPS(0.998)PLLS(0.002)ELLK;AT(1)PPPS(0.987)PLLS(0.013)ELLK 120.32 0.0023579 4009600.0 16946.9 17566.0 22234.3 22254.5 26068.5 23225.9 24749.8 22920.2 19592.3 23264.7 True False 19815.675453467797 19309.836390350327 22764.450036052316 21007.652515062477 20960.564559293045 22007.89291713983 22405.31977096513 22318.56903595929 19878.800322509964 27482.40594673612 0.7210313206155503 0.7026253970549333 0.8283281340131678 0.7644036899745089 0.7626903044775952 0.8007993535862002 0.81526049118076 0.8121038994626271 0.7233282399305663 1.0 14.746220689945783 -14.52287874518317 0.24296558263210044 2.3006065513623404 0.7516460233218527 0.7265546778454939 0.0421448871851542 94.11200599974146 0.9354513247282328 60.680214608323645 0.06629012959781759 3.000000000671205e-15 14.52287874518317 -1.5489605280404877 AT(ph)PPPS(ph)PLLSELLK ddPTM_PC-9_Lapatinib_30min_R1 3 ATPPPSPLLSELLK 14 0 Q9H0E9-3;H7C128;H7C179;H7C127;Q9H0E9-4;Q9H0E9-2 Q9H0E9-3 BRD8 Bromodomain-containing protein 8 2 AT(1)PPPS(0.999)PLLS(0.001)ELLK;AT(1)PPPS(1)PLLSELLK;AT(1)PPPS(0.999)PLLS(0.001)ELLK 142.45 0.0017904 9148000.0 48076.7 51279.7 55173.6 47553.7 53599.1 46521.0 54957.0 53352.0 57404.0 53029.0 True False 47391.117441813025 51160.965005265374 50637.43958425504 51050.95773249284 50446.506317885025 44531.40527574767 57802.40455333379 55830.92869105169 50938.55702908171 62194.99199329903 0.7619764216211975 0.8225897836079394 0.8141722984659405 0.8208210355263513 0.8111023846312287 0.715996639738221 0.9293739367240613 0.8976756311354938 0.8190138047540854 1.0 15.924510797247645 -9.512382438953706 0.2806153797758504 1.0573778382803976 0.7818027854464196 0.5556751942592848 0.05205573429520898 4.74079279835306 0.5796364102763991 0.37003622206510234 0.0786582467162568 3.0733892016533205e-10 9.512382438953706 -0.275575052833978 AT(ph)PPPS(ph)PLLSELLKK ddPTM_PC-9_AZD4547_30min_R2 5 ATPPPSPLLSELLKK 15 1 Q9H0E9-3;H7C128;H7C179;H7C127;Q9H0E9-4;Q9H0E9-2 Q9H0E9-3 BRD8 Bromodomain-containing protein 8 2 AT(1)PPPS(1)PLLSELLKK;AT(1)PPPS(1)PLLSELLKK;AT(1)PPPS(1)PLLSELLKK;AT(1)PPPS(1)PLLSELLKK;AT(1)PPPS(1)PLLSELLKK 116.13 0.0009881 926620.0 29940.800000000003 24643.4 33904.200000000004 47380.1 48310.0 41140.100000000006 32316.199999999997 40027.6 33325.1 37350.5 True False 39461.3515926721 32608.897122047412 33454.60815538926 36457.34996024787 41602.99039130006 38567.60304345052 35192.27919522528 33842.25416274297 35086.59675145997 36042.87036360742 1.0948448665319488 0.9047253116381291 0.9281893427990814 1.0114996278725612 1.1542640741872408 1.070048047072087 0.9764005707702741 0.9389444797635645 0.9734684390421634 1.0 15.137426287883082 -7.4939363138556185 21.249877614103724 0.9652583692799466 1.0223267515211454 0.12434863040116739 0.0705121550445081 262.87588292235165 193008.17989600135 0.033060371813055336 0.02220328552152114 3.206739535185597e-08 7.4939363138556185 0.05706838224119881 AT(ph)PPPS(ph)PLLSELLKK ddPTM_PC-9_Lapatinib_30min_R1 3 ATPPPSPLLSELLKK 15 1 Q9H0E9-3;H7C128;H7C179;H7C127;Q9H0E9-4;Q9H0E9-2 Q9H0E9-3 BRD8 Bromodomain-containing protein 8 2 AT(1)PPPS(1)PLLSELLKK;AT(1)PPPS(0.998)PLLS(0.002)ELLKK;AT(1)PPPS(1)PLLSELLKK 87.24 0.010766 428920.0 11415.9 8347.89 9593.8 10367.4 12513.8 14009.800000000001 8623.8 9888.7 12151.5 9251.6 True False 11253.10717258033 8328.560973597829 8805.034797138951 11129.853180632554 11777.762887077393 13410.6335124389 9070.298167422532 10348.165102474186 10782.870109032241 10850.726733017882 1.0370832709608322 0.7675578952932888 0.8114695922021465 1.025724216864232 1.0854353977267361 1.2359203067598625 0.8359161916613704 0.9536840579521332 0.9937463521425566 1.0 13.405504050699369 -5.771620171897529 24.95534652828455 1.0209265060458101 0.8615890183193796 0.2525522680848762 0.1151024964110279 263.73334409890737 646468.3328083574 0.03392988411072399 0.05097044230697301 1.6919200152051765e-06 5.771620171897529 -0.15933748772643053 AT(ph)PPPSPLLSELLK ddPTM_PC-9_AZD4547_30min_R2 3 ATPPPSPLLSELLK 14 0 Q9H0E9-3;H7C128;H7C179;H7C127;Q9H0E9-4;Q9H0E9-2 Q9H0E9-3 BRD8 Bromodomain-containing protein 8 1 AT(0.992)PPPS(0.008)PLLSELLK;AT(1)PPPSPLLSELLK;AT(0.996)PPPS(0.004)PLLSELLK 93.71600000000001 0.011339 2202200.0 6175.1 8279.2 7496.320000000001 10808.440000000002 13837.99 10948.35 9961.5 11791.2 8739.8 11464.69 True False 8138.653349940865 10955.289491419813 7396.913898791529 8316.721146733373 11916.823949594414 10263.74794375223 10848.05420201746 9969.140974820746 9201.767985344675 11063.314692680051 0.7356433018510932 0.9902357291407691 0.6685983454565959 0.7517386405211868 1.0771476976496999 0.9277281021883209 0.9805428574851065 0.9010989248472471 0.8317369830791261 1.0 13.433496077439983 -6.23913509418939 24.97613489297539 0.9482066901506033 0.79267728485808 0.4084845351935166 0.09793439213766944 887.388305958677 993689.2309879815 0.029131208225446244 0.03757857106521354 5.765870789341048e-07 6.23913509418939 -0.15552940529252335 AT(ph)PPPSPLLSELLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ATPPPSPLLSELLK 14 0 Q9H0E9-3;H7C128;H7C179;H7C127;Q9H0E9-4;Q9H0E9-2 Q9H0E9-3 BRD8 Bromodomain-containing protein 8 1 AT(0.999)PPPS(0.001)PLLSELLK;AT(1)PPPSPLLSELLK;AT(0.999)PPPS(0.001)PLLSELLK 130.47 4.7375e-05 31661500.0 22067.1 26053.5 22550.3 25391.199999999997 28745.9 20513.3 26495.4 20279.9 17120.2 17551.0 True False 25802.624184908116 28639.91929841693 23087.984674488987 23968.613383381093 23113.34724916975 19437.546436399203 23985.563901915568 19747.574113330214 17370.550536763683 20732.857366360455 1.2445281289000463 1.3813783017137748 1.1135939569984108 1.1560689855644657 1.1148172603874513 0.9375237620617154 1.156886553458507 0.9524772087310606 0.8378271373702598 1.0 14.33963133942179 -5.8044029879172445 0.48747748319363426 0.93981039041196 1.3976659793670527 0.6514912500918688 0.09004320135754633 1.1661538163588965 0.4261179585930859 0.06993330095630415 0.2781997938084844 1.56890631859926e-06 5.8044029879172445 0.4578555889550927 AT(ph)PPPSPLLSELLK ddPTM_PC-9_Lapatinib_30min_R1 1 ATPPPSPLLSELLK 14 0 Q9H0E9-3;H7C128;H7C179;H7C127;Q9H0E9-4;Q9H0E9-2 Q9H0E9-3 BRD8 Bromodomain-containing protein 8 1 AT(0.999)PPPS(0.001)PLLSELLK 83.087 0.020733 1368900.0 922.81 2227.1 2395.6 3031.7 2041.2 2082.9 923.23 1188.2 1214.9 712.25 True False 909.6505601773714 2221.9432867826154 2198.6430152834205 3254.661331454726 1921.140629153604 1993.81922247705 971.030332000916 1243.4081097373598 1078.0651685358403 835.3614634865311 1.0889304809211349 2.659858497073753 2.63196605467888 3.896111412502574 2.2997716714575014 2.3867742404054497 1.162407382246419 1.4884671655163177 1.2905373489894323 1.0 9.706256781061844 -7.184675659663243 3.5850153443964654 1.2679678302550639 2.5889414092195615 0.4726175988684138 0.648128417519568 0.22797109314370786 5.667561976276781 0.27722425945758333 0.20510799976591085 6.536185065910435e-08 7.184675659663243 1.3209735789644976 AT(ph)PPPSPLLSELLKK ddPTM_PC-9_AZD4547_30min_R2 2 ATPPPSPLLSELLKK 15 1 Q9H0E9-3;H7C128;H7C179;H7C127;Q9H0E9-4;Q9H0E9-2 Q9H0E9-3 BRD8 Bromodomain-containing protein 8 1 AT(1)PPPSPLLSELLKK;AT(0.981)PPPS(0.019)PLLSELLKK 90.42200000000001 0.0035866 21763000.0 48576.0 35774.0 57056.0 68652.0 71386.0 55824.0 52658.0 51380.0 54392.0 54121.0 True False 64022.157556432714 47337.245901301125 56299.40016027184 52825.34206282678 61475.28611205437 52333.31645517585 57344.45998793707 43440.401594942836 57267.050076531166 52226.240263150314 1.22586188923129 0.9063881616364646 1.0779906781839599 1.011471279507347 1.177095762633903 1.0020502374187001 1.0980009225055793 0.8317734796926102 1.0965187190956485 1.0 15.672487228215694 AT(ph)PPPSPLLSELLKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATPPPSPLLSELLKK 15 1 Q9H0E9-3;H7C128;H7C179;H7C127;Q9H0E9-4;Q9H0E9-2 Q9H0E9-3 BRD8 Bromodomain-containing protein 8 1 AT(0.985)PPPS(0.015)PLLSELLKK;AT(0.999)PPPS(0.001)PLLSELLKK 67.153 0.025817000000000003 22577000.0 60171.2 36391.7 43732.8 59211.3 56421.5 56975.9 57245.1 57767.2 58592.1 48413.1 True False 70356.99572462817 40004.42747163338 44775.55580956759 55893.88282662465 45366.1121001267 53987.983503660405 51822.42970936638 56250.87220940775 59448.89861713713 57190.011792111254 1.2302322297183572 0.699500248698175 0.782926151026671 0.9773364452135785 0.7932523648541102 0.9440107076723399 0.9061447634902345 0.9835786083395589 1.0394979254985477 1.0 15.803475582562562 -7.785592731279441 1.8477479658526075 1.0223656707351596 0.887947643718083 0.10382206221887491 0.1358879832532853 0.7415701550637172 4.869677199531171 0.09874609848462627 0.038981351877000484 1.6383522002502694e-08 7.785592731279441 -0.1344180270170766 AT(ph)PPPSPLLSELLKK ddPTM_PC-9_Lapatinib_30min_R1 2 ATPPPSPLLSELLKK 15 1 Q9H0E9-3;H7C128;H7C179;H7C127;Q9H0E9-4;Q9H0E9-2 Q9H0E9-3 BRD8 Bromodomain-containing protein 8 1 AT(1)PPPSPLLSELLKK;AT(1)PPPSPLLSELLKK 82.449 0.0066086 17531800.0 53377.0 35056.5 44814.5 48640.2 39211.6 39986.7 26188.6 23345.3 36533.2 29708.3 True False 52615.834191857 34975.32882811496 41130.02479897261 52217.36256695059 36905.25078097173 38276.56205455043 27544.51756619605 24430.007864207684 32418.446304348978 34843.34007117853 1.5100686123767852 1.0037880627019913 1.1804271552311445 1.4986325208857743 1.0591766089468202 1.0985330905808244 0.790524602691007 0.7011385192780507 0.9304058175285165 1.0 15.08859530638974 -6.912326547991137 1.8719100699217013 0.8337170703844674 1.2609902934619241 0.5543953744697037 0.16793798162464207 0.2555523789939669 1.827512577346155 0.07280152357898051 0.0597086190780771 1.2236957508773263e-07 6.912326547991137 0.42727322307745674 AT(ph)PSENLVPSSAR ddPTM_PC-9_AZD4547_30min_R2 1 ATPSENLVPSSAR 13 0 Q8N684-2;Q8N684;Q8N684-3;F5H669;F5H6M0;F5H047 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 1 AT(0.89)PS(0.085)ENLVPS(0.013)S(0.013)AR 115.12 0.00071971 17307000.0 7759.5 14157.0 15430.0 13171.0 15219.0 17131.0 14559.0 20847.0 16294.0 15259.0 True False 10226.859592373588 18732.97339477611 15225.388118217106 10134.62943992151 13106.104549062211 16059.795861880519 15854.722795479809 17625.57516640275 17155.26757513972 14724.787054478136 0.6945336156330608 1.2722067440071396 1.0339971683044968 0.6882700172454679 0.8900709056486051 1.0906640484825467 1.0767369834837806 1.1970003437871393 1.1650604868966454 1.0 13.845959149926422 -6.840666128938869 5.385665625848593 1.1197028015747692 0.9298355871964172 0.24913898968328108 0.1636802153104548 0.3296446605427692 16.38969239812304 0.060572873466354475 0.05372212802716075 1.4432244277928635e-07 6.840666128938869 -0.18986721437835197 AT(ph)PSENLVPSSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATPSENLVPSSAR 13 0 Q8N684-2;Q8N684;Q8N684-3;F5H669;F5H6M0;F5H047 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 1 AT(0.758)PS(0.099)ENLVPS(0.049)S(0.094)AR 90.853 0.013213999999999998 5591900.0 6951.1 10825.0 10704.0 7109.8 8237.6 6005.1 7817.3 3190.2 6137.2 6576.9 True False 8127.783939516965 11899.634460067302 10959.223955146057 6711.460956282604 6623.501414106385 5690.181984625628 7076.788751649133 3106.460630296303 6226.9449395583015 7769.239907288241 1.046149177591025 1.5316343171362725 1.4105915232280737 0.8638503941661853 0.8525288822517824 0.7323987999505239 0.9108727283618148 0.3998409969786318 0.8014870198199017 1.0 12.923557746148946 -5.833275572179034 4.5559877889801985 0.7656604044213712 1.350636357087623 0.6304424680219438 0.18761548311274864 0.12192521598734476 4.789905055761545 0.053074533739389106 0.08242945229815427 1.467994497867323e-06 5.833275572179034 0.5849759526662518 AT(ph)PSENLVPSSAR ddPTM_PC-9_Lapatinib_30min_R1 1 ATPSENLVPSSAR 13 0 Q8N684-2;Q8N684;Q8N684-3;F5H669;F5H6M0;F5H047 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 1 AT(0.984)PS(0.016)ENLVPSSAR 130.47 0.00019598 18498000.0 8094.2 10150.0 13758.0 11660.0 13228.0 12370.0 7983.5 13077.0 16170.0 11345.0 True False 7978.775223705514 10126.498298614148 12626.870347415797 12517.515296619753 12449.955047248624 11840.963935878397 8396.846566434491 13684.60515993558 14348.76432235125 13305.968133737728 0.5996388345072812 0.7610493424328946 0.9489629180307403 0.940744421661523 0.9356669820726045 0.8898987143863089 0.6310586709691575 1.0284561801435406 1.0783705610995322 1.0 13.699785863297693 -4.96771158724773 2.569546340117663 0.9208576539567769 0.5867772419640581 0.4630361805571147 0.11402577551652092 0.3391639745488886 3.823301857441718 0.03185274967500847 0.20792727565747643 1.0771803261175442e-05 4.96771158724773 -0.33408041199271876 AT(ph)PTKAPAPVVLGSPVVLGPPVGQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATPTKAPAPVVLGSPVVLGPPVGQAR 26 1 A0A0C4DFM2;Q6ZN55;Q6ZN55-2 A0A0C4DFM2 ZNF574 Zinc finger protein 574 1 AT(0.982)PT(0.018)KAPAPVVLGSPVVLGPPVGQAR 94.72 0.00043557 0.0 1852.8 4251.1 5089.6 4361.6 1412.3 3699.0 4935.5 3088.2 4006.9 3625.4 True False 2166.442445531934 4673.121113458857 5210.95536641549 4117.233692497988 1135.5699532803797 3505.017928282659 4467.973710074363 3007.1380222183698 4065.493332189951 4282.656321349392 0.5058641840420491 1.0911735060698113 1.2167577726091285 0.9613738258597221 0.2651555175276313 0.8184214808014965 1.0432715994045914 0.7021665519195507 0.9492924547606434 1.0 12.064290191781536 -7.478361017101571 0.007026326242954947 1.7182727275023901 9.655332157038803e-05 0.01186755099213066 0.2736490150368121 48155.607148143186 251.59053075703267 30519.32779086628 30980.277907572072 3.323831374278072e-08 7.478361017101571 -1.7181761741808197 AT(ph)QFIQR ddPTM_PC-9_AZD4547_30min_R2 1 ATQFIQR 7 0 J9JIG6;Q96EG1 J9JIG6 ARSG Arylsulfatase G 1 AT(1)QFIQR 99.384 0.028995 14719000.0 11431.0 5277.8 10666.0 6591.7 14221.0 16185.0 3608.6 11182.0 3952.6 13174.0 True False 15065.820220429478 6983.745636995784 10524.56187095941 5072.085405749798 12246.659622328245 15172.949391427013 3929.7584092154975 9454.078836797406 4161.526366607172 12712.782269853513 1.1850922874810692 0.5493483242890665 0.8278724237979639 0.39897524382034766 0.9633343325142436 1.1935191738009565 0.30911867487374023 0.7436671718366764 0.32734977114141395 1.0 13.633992187047905 -7.277347836482166 24.98486429307229 0.5736728833676292 0.8224525610578354 0.14692769208696188 0.2973736714446183 1704.7585838802818 2677380.436404973 0.12144893411838327 0.08217297976847923 5.280221772143799e-08 7.277347836482166 0.24877967769020615 AT(ph)QFIQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ATQFIQR 7 0 J9JIG6;Q96EG1 J9JIG6 ARSG Arylsulfatase G 1 AT(1)QFIQR;AT(1)QFIQR;AT(1)QFIQR;AT(1)QFIQR 122.15 0.00022211 29151800.0 59703.0 58545.0 58394.5 58496.3 65465.0 42130.2 43022.7 51908.6 50854.5 49270.7 True False 69809.53871199976 64356.96068957413 59786.84634237449 55218.94195856339 52637.6031944346 39920.81814602165 38947.27839862553 50546.05425170794 51598.15085523819 58203.087883353415 1.199412973619324 1.1057310364452464 1.0272109009438664 0.9487287353074695 0.9043781886611795 0.6858883196374079 0.6691617200221569 0.8684428282054181 0.8865191303706708 1.0 15.828808074879317 -5.715685610675248 1.156716236171834 0.809659111858973 1.1780882707758424 0.6426684199112954 0.09491728032290828 0.34872313941624467 0.893627085111633 0.03593952366535644 0.1048072437936093 1.924484374742352e-06 5.715685610675248 0.36842915891686945 AT(ph)QFIQR ddPTM_PC-9_Lapatinib_30min_R1 4 ATQFIQR 7 0 J9JIG6;Q96EG1 J9JIG6 ARSG Arylsulfatase G 1 AT(1)QFIQR;AT(1)QFIQR;AT(1)QFIQR;AT(1)QFIQR 105.27 0.025006999999999998 39751200.0 79759.9 73928.7 100198.3 78614.1 105236.3 111730.6 74567.9 81516.9 96474.8 80826.6 True False 78622.50919982571 73757.52263731565 91960.38255062308 84395.64316294991 99046.50773652628 106952.14269474975 78428.66099846312 85304.47276607435 85608.792099318 94797.37011532544 0.8293743708731345 0.7780545235335766 0.9700731406235107 0.890274097902491 1.0448233702689387 1.1282184575862966 0.8273295018949469 0.8998611740209403 0.9030713826256034 1.0 16.53255941573832 -5.264201598667105 24.889182106585945 0.9564807166799943 0.8037144398886584 0.3594031589691209 0.08235017139705322 244.20548880215696 2200454.7600773536 0.0229361144587247 0.05140375004446606 5.442499544089459e-06 5.264201598667105 -0.15276627679133592 AT(ph)S(ph)ST(ph)S(ph)VTNS(ph)TGSALPK ddPTM_PC-9_Lapatinib_30min_R1 1 ATSSTSVTNSTGSALPK 17 0 Q8WXI7 Q8WXI7 MUC16 Mucin-16 5 AT(0.595)S(0.595)S(0.595)T(0.712)S(0.712)VT(0.681)NS(0.541)T(0.541)GS(0.03)ALPK 44.299 0.045646 0.0 3490.7 3074.7 3211.1 1997.1 3302.1 4225.5 3465.2 3526.0 3435.4 3585.6 True False 3440.921977884019 3067.580721059006 2947.095753204453 2143.973396130302 3107.876970178386 4044.785215121596 3644.611100646182 3689.830832295852 3048.4690756342316 4205.3661824883175 0.8182217263772316 0.7294443784307784 0.7007940867257973 0.509818480268872 0.7390264807664034 0.9618152235980303 0.8666572523036896 0.8774101165460405 0.7248997931092057 1.0 12.038015713361023 -6.592825203105252 6.662155473372917 0.8760047980101311 0.6849371205135347 0.47827374765264585 0.0981958236018743 0.19851850540585728 15.075562471319433 0.03330739802035573 0.033326174104465624 2.553728932729711e-07 6.592825203105252 -0.19106767749659637 AT(ph)SFEESER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATSFEESER 9 0 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 AT(0.514)S(0.486)FEESER 133.99 0.0027884 122810000.0 73271.0 62886.0 57708.0 69998.0 80597.0 69026.0 69218.0 78214.0 59641.0 59683.0 True False 85674.3331317844 69128.9064809046 59083.97757880869 66076.23899657799 64804.596420405505 65406.15504667171 62661.16994507695 76160.96537458319 60513.13679531328 70503.05544963201 1.2151861020121444 0.9805093699845516 0.8380342837909882 0.937210998518829 0.9191742968743031 0.9277066735554238 0.8887724020676329 1.0802505634524342 0.8583051671929933 1.0 16.105398161692257 -4.782835184985945 3.9077656100206353 0.9309436419493506 1.241510701355579 0.6246589989323543 0.06567568241012889 0.14568570865304697 4.083211585916649 0.015803972886182908 0.12869891375816192 1.6487879888326326e-05 4.782835184985945 0.3105670594062284 AT(ph)SGSSLPVGINR ddPTM_PC-9_AZD4547_30min_R2 1 ATSGSSLPVGINR 13 0 Q13905-2;Q13905;Q13905-4;Q13905-3 Q13905-2 RAPGEF1 Rap guanine nucleotide exchange factor 1 1 AT(0.866)S(0.134)GSSLPVGINR 139.19 0.00016468 5463000.0 22839.0 28532.0 31277.0 55142.0 42080.0 42324.0 30944.0 41150.0 34046.0 32485.0 True False 30101.32691928869 37754.41102632985 30862.246543971254 42429.86383540746 36237.91835367221 39677.47358929607 33697.95605352891 34791.2130329291 35845.60205371345 31347.71003766447 0.9602400584642947 1.2043754067192687 0.9845135898887055 1.3535235519413606 1.155998901040367 1.2657215963023563 1.0749734514272529 1.1098486298082777 1.143483910328529 1.0 14.936072436995543 -10.50216043182888 9.348356262571269 1.0002506162202294 1.1443281971825292 0.1187128411207643 0.11299105052142201 1.4925608932394522e-10 0.0 0.10519390904078571 0.025513270479222125 3.146585725636377e-11 10.50216043182888 0.14407758096229983 AT(ph)SGSSLPVGINR ddPTM_PC-9_Lapatinib_30min_R1 2 ATSGSSLPVGINR 13 0 Q13905-2;Q13905;Q13905-4;Q13905-3 Q13905-2 RAPGEF1 Rap guanine nucleotide exchange factor 1 1 AT(0.953)S(0.043)GS(0.004)SLPVGINR;AT(0.884)S(0.116)GSSLPVGINR 156.52 0.00022557 10811000.0 41518.0 48967.0 64865.0 36155.0 64037.0 72287.0 58032.0 59778.0 85651.0 52874.0 True False 40925.94570653125 48853.61992002351 59532.05008614089 38813.95930954434 60270.46956158599 69195.45351922733 61036.61300724323 62555.50411031802 76004.08243498493 62013.20044982355 0.6599553870735227 0.7877938820389091 0.959989964303 0.6258983414498934 0.9718974206201848 1.1158181325476844 0.9842519425622855 1.0087449713377277 1.2256113518359975 1.0 15.920287727249418 -6.4656340614025005 5.9760871709639645 1.0608239949838236 0.7757891794506924 0.6526335114572819 0.1061008325035108 0.14414282879125767 11.075467693334215 0.033017325978464705 0.036994214284217466 3.4226771745350264e-07 6.4656340614025005 -0.28503481553313126 AT(ph)SNVFAMFDQSQIQEFK ddPTM_PC-9_AZD4547_30min_R2 7 ATSNVFAMFDQSQIQEFK 18 0 J3QRS3;P19105;O14950;J3KTJ1;P24844;P24844-2 J3QRS3 MYL12A;MYL12B;MYL9 Myosin regulatory light chain 12A;Myosin regulatory light chain 12B;Myosin regulatory light polypeptide 9 1 AT(0.5)S(0.5)NVFAMFDQSQIQEFK;AT(0.5)S(0.5)NVFAMFDQSQIQEFK;AT(0.5)S(0.5)NVFAMFDQSQIQEFK;AT(0.5)S(0.5)NVFAMFDQSQIQEFK;AT(0.5)S(0.5)NVFAMFDQSQIQEFK;AT(0.5)S(0.5)NVFAMFDQSQIQEFK;AT(0.593)S(0.407)NVFAMFDQSQIQEFK 223.7 1.7734e-34 320991400.0 609404.6 647601.8 722889.6 826365.2 778236.7 765532.2 684790.3 832361.7 706268.5 711682.7000000001 True False 803182.5863968786 856926.4173065702 713303.6115763262 635859.4703550694 670191.9675482713 717663.350516389 745735.3100854089 703739.3250340474 743600.4110342802 686766.9052923552 1.1695126544500065 1.2477689456246854 1.0386400481436628 0.9258737796696614 0.9758652643038644 1.044988255820046 1.0858637833865201 1.024713508485775 1.08275516089077 1.0 19.389460993216304 -5.304855080116194 6.966918904391817 1.020719962335955 1.2084980378795829 0.703122355717359 0.04843800496844498 0.11695607514547184 15.70029972974712 0.01373981801784742 0.029342061940706148 4.95615545346442e-06 5.304855080116194 0.1877780755436278 AT(ph)SNVFAMFDQSQIQEFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ATSNVFAMFDQSQIQEFK 18 0 J3QRS3;P19105;O14950;J3KTJ1;P24844;P24844-2 J3QRS3 MYL12A;MYL12B;MYL9 Myosin regulatory light chain 12A;Myosin regulatory light chain 12B;Myosin regulatory light polypeptide 9 1 AT(0.5)S(0.5)NVFAMFDQSQIQEFK;AT(0.5)S(0.5)NVFAMFDQSQIQEFK;AT(0.5)S(0.5)NVFAMFDQSQIQEFK;AT(0.5)S(0.5)NVFAMFDQSQIQEFK 143.48 4.0818e-05 393464000.0 1148684.0 1231870.0 1388908.0 1260854.0 1855721.0 1373803.0 1447696.0 1247096.0 1191902.0 1023577.0 True False 1343133.5136568474 1354161.9124547879 1422024.8341829237 1190212.438123823 1492105.7914546619 1301758.3522380383 1310559.754468611 1214361.0514074347 1209331.3118929537 1209143.407468926 1.1108140733020246 1.1199349093664797 1.176059700941196 0.9843434871098286 1.2340188783545991 1.0765955007462524 1.0838745399207672 1.0043151572479154 1.0001554029264577 1.0 20.20555393134275 -7.613946927291964 1.9242328654803234 0.9965387442787392 1.1195944186691325 0.42335888976445524 0.060351404834113366 0.3298833080263733 2.4106759327231893 0.03757080513126881 0.017521171943140398 2.432501253331465e-08 7.613946927291964 0.12305567439039322 AT(ph)SNVFAMFDQSQIQEFK ddPTM_PC-9_Lapatinib_30min_R1 5 ATSNVFAMFDQSQIQEFK 18 0 J3QRS3;P19105;O14950;J3KTJ1;P24844;P24844-2 J3QRS3 MYL12A;MYL12B;MYL9 Myosin regulatory light chain 12A;Myosin regulatory light chain 12B;Myosin regulatory light polypeptide 9 1 AT(0.5)S(0.5)NVFAMFDQSQIQEFK;AT(0.5)S(0.5)NVFAMFDQSQIQEFK;AT(0.797)S(0.203)NVFAMFDQSQIQEFK;AT(0.5)S(0.5)NVFAMFDQSQIQEFK;AT(0.5)S(0.5)NVFAMFDQSQIQEFK 140.4 4.8472e-05 182150500.0 474959.0 763666.0 861067.0 702999.0 836913.0 831265.0 805767.0 793920.0 894728.0 650375.0 True False 468185.997563187 761897.7782965006 790273.3950747396 754699.8915959179 787687.422774265 795713.7337233592 847485.6726117885 830808.421547454 793954.3107364677 762791.452179786 0.6137798165216434 0.9988284164947946 1.0360281212072053 0.9893921719222922 1.0326379779470984 1.0431602654296832 1.1110319474477284 1.0891684996905768 1.0408537070881292 1.0 19.540929151376773 -4.75246933950692 3.6984988736880022 1.0450989401526039 0.5522422354730732 0.9331064700599064 0.034239055157861374 0.07653696016451415 1.746990008465107 0.00967696816831283 0.10862925031250743 1.768197045200173e-05 4.75246933950692 -0.4928567046795307 AT(ph)SPEAGGGGGALK ddPTM_PC-9_Lapatinib_30min_R1 2 ATSPEAGGGGGALK 14 0 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 AT(0.596)S(0.404)PEAGGGGGALK;AT(0.913)S(0.087)PEAGGGGGALK 161.87 0.00077083 50832600.0 171480.0 136494.0 164129.0 154982.0 145119.0 127110.0 134126.0 111961.0 153721.0 108341.0 True False 169034.66375441948 136177.95652916632 150634.94717626195 166379.89328479613 136583.3857349315 121673.80160788212 141070.38799644166 117163.11679372525 136407.32222610753 127067.59749469187 1.330273547994647 1.071696948821709 1.1854709630640068 1.3093809638743386 1.0748876065012336 0.9575517599045259 1.1101995377093263 0.9220534511059724 1.0735020171590621 1.0 16.955236661400477 -6.464589213968474 6.114138247489941 1.0138742810261274 1.2096748147526575 0.5910187814707595 0.08295080024394375 0.16298473842865613 12.933772241519389 0.025199363829905907 0.028267113536597936 3.430921536219473e-07 6.464589213968474 0.19580053372653006 AT(ph)SPESTSR ddPTM_PC-9_AZD4547_30min_R2 1 ATSPESTSR 9 0 Q8N3X1-2;Q8N3X1 Q8N3X1-2 FNBP4 Formin-binding protein 4 1 AT(0.615)S(0.385)PESTSR 108.43 0.0059562 106470000.0 51096.0 33865.0 40278.0 53898.0 51952.0 47408.0 42226.0 40649.0 49346.0 64828.0 True False 67343.46513717661 44811.198983830785 39743.88740282231 41472.64881579906 44739.36155679612 44443.57026560219 45984.032197398876 34367.631071094416 51954.32881814437 62558.3914521075 1.076489717430353 0.7163099616801475 0.6353086529286615 0.6629430177652356 0.715161635686349 0.7104333924510611 0.7350577777020151 0.5493688420266538 0.8304933616766469 1.0 15.932915797023641 -8.530351899603128 23.540730057917777 1.0000000095215198 0.7174467334570396 0.30013304085697357 0.12932332000818852 509.3674886489041 1604530.59612661 0.12332997730080462 0.031843663284646495 2.948818893002625e-09 8.530351899603128 -0.2825532760644802 AT(ph)SPLVSLYPALECR ddPTM_PC-9_AZD4547_30min_R2 2 ATSPLVSLYPALECR 15 0 A0A087WXV6;Q96G74-2;Q96G74-3;Q96G74-5;Q96G74;H7BZQ3;Q96G74-4 A0A087WXV6 OTUD5 OTU domain-containing protein 5 1 AT(0.5)S(0.5)PLVSLYPALECR;AT(0.629)S(0.371)PLVSLYPALECR 222.75 3.0432e-19 49848000.0 32869.0 29463.0 40382.0 60261.0 51789.0 42779.0 32985.0 44629.0 37301.0 38160.0 True False 43320.658282328455 38986.33856963255 39846.508294869935 46368.75747316907 44598.9912932113 40104.02236736833 35920.601099588 37732.61352239595 39272.654708499234 36824.03001500004 1.1764236088413478 1.0587200410642645 1.0820789652473861 1.2591983401675766 1.2111382506217863 1.0890720638407096 0.9754663214470541 1.0246736575824482 1.0664952937661023 1.0 15.16835990315464 -7.007652291884551 5.997253757560427 1.0199812621301942 1.1535392403673033 0.5660938904445247 0.0580508895145838 0.1369015913713195 19.71614653518421 0.02379671452780041 0.019647876018270647 9.825342721805343e-08 7.007652291884551 0.13355797823710902 AT(ph)SPLVSLYPALECR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ATSPLVSLYPALECR 15 0 A0A087WXV6;Q96G74-2;Q96G74-3;Q96G74-5;Q96G74;H7BZQ3;Q96G74-4 A0A087WXV6 OTUD5 OTU domain-containing protein 5 1 AT(0.907)S(0.093)PLVSLYPALECR;AT(0.5)S(0.5)PLVSLYPALECR;AT(0.5)S(0.5)PLVSLYPALECR;AT(0.616)S(0.384)PLVS(0.001)LYPALECR 199.38 1.4077999999999998e-09 48886000.0 58563.3 63185.8 72248.5 78179.0 84805.0 76904.2 70125.8 69834.0 68616.0 56204.4 True False 68476.91001210075 69458.46864359536 73971.17824396216 73798.88408973788 68188.06902778636 72871.20836989328 63482.97655717407 68000.93149523929 69619.37919128148 66393.81280621441 1.0313748694018574 1.0461587564842203 1.114127583843754 1.111532550557638 1.0270244492029537 1.0975602287307198 0.956158019459791 1.0242058502305873 1.0485823339364713 1.0 16.018761183626268 -7.245098395168656 24.97548958667177 1.0092537002791269 1.0719172118758418 0.4304603539393371 0.036064231966978805 827.005414303542 1263992.7456374776 0.014277119323205755 0.011023470818697374 5.68724064274637e-08 7.245098395168656 0.0626635115967149 AT(ph)SPLVSLYPALECR ddPTM_PC-9_Lapatinib_30min_R1 2 ATSPLVSLYPALECR 15 0 A0A087WXV6;Q96G74-2;Q96G74-3;Q96G74-5;Q96G74;H7BZQ3;Q96G74-4 A0A087WXV6 OTUD5 OTU domain-containing protein 5 1 AT(0.498)S(0.498)PLVS(0.003)LY(0.001)PALECR;AT(0.624)S(0.376)PLVSLYPALECR 162.67 0.00079319 66751000.0 23394.0 23653.0 26585.0 22720.0 23544.0 26212.0 23571.0 24144.0 25903.0 21634.0 True False 23060.39727006581 23598.232931735987 24399.28392106768 24390.904591698192 22159.188209284966 25090.9738631564 24791.39104621124 25265.81838200539 22985.53136931755 25373.408074507002 0.9088411459095593 0.9300379697690451 0.9616084622696768 0.9612782216750794 0.8733232896509711 0.9888688894088938 0.977061929300679 0.9957597461016792 0.9058905804778907 1.0 14.631029690120803 AT(ph)SVDYSSFADR ddPTM_PC-9_AZD4547_30min_R2 1 ATSVDYSSFADR 12 0 Q86YS7-3;Q86YS7-2;Q86YS7-4 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 AT(0.949)S(0.051)VDYSSFADR 155.47 0.00078407 5426800.0 23325.0 22929.0 27133.0 40185.0 34924.0 28147.0 24383.0 40484.0 26592.0 28281.0 True False 30741.86480986068 30340.350848966686 26773.19869161275 30920.969102061037 30075.40543212093 26386.963640438426 26553.03976387008 34228.12802977162 27997.598831356045 27290.890798066437 1.1264514975831696 1.1117391174023643 0.9810305896467708 1.1330142841746957 1.1020309177394743 0.9668780632953156 0.9729634682995165 1.2541960716136349 1.025895381668512 1.0 14.736131865732718 -5.027302512129407 24.268117567098866 1.0609959579110375 1.122773496107384 0.08184770772890038 0.08495012280528544 1221.3442461031425 1085610.5638546715 0.021845395940494873 0.05819655726030964 9.390689648929049e-06 5.027302512129407 0.06177753819634657 AT(ph)T(ph)LASTLMEQYMK ddPTM_PC-9_Lapatinib_30min_R1 1 ATTLASTLMEQYMK 14 0 E9PGC0;P20936-2;P20936-4;P20936 E9PGC0 RASA1 Ras GTPase-activating protein 1 2 AT(0.964)T(0.964)LAS(0.034)T(0.034)LMEQY(0.005)MK 72.006 0.028176999999999997 0.0 5086.3 5214.3 4671.6 6942.6 2430.1 1602.7 4495.0 5653.2 2745.0 2676.6 True False 5013.768429286814 5202.226608715636 4287.5190808974885 7453.181963834677 2287.1662957604235 1534.1562570761764 4727.729105796083 5915.868310021244 2435.8291938685334 3139.2467436546826 1.5971246731150004 1.657157602928418 1.365779574212761 2.3741943760552413 0.7285716869447877 0.48870203024886333 1.5060074890105972 1.8844865641666777 0.7759279192666337 1.0 11.616202713345361 -6.279045261658667 24.995266108389355 1.1015141790688179 1.7146933577460308 0.35943578854209823 0.44513061010982374 1088.6587765041004 1545577.1345449607 0.14662100179873838 0.16661070088958327 5.259624483482094e-07 6.279045261658667 0.6131791786772129 AT(ph)TPASTANSDVATIPTDTPLKEENEGFVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATTPASTANSDVATIPTDTPLKEENEGFVK 30 1 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 AT(0.51)T(0.467)PAS(0.02)T(0.002)ANSDVATIPTDTPLKEENEGFVK 72.87899999999999 1.7134000000000002e-05 3469200.0 11212.0 12608.0 11015.0 14687.0 18770.0 20772.0 29317.0 20926.0 22152.0 19270.0 True False 13109.970152905902 13859.638916630804 11277.639374620132 13864.135005896456 15092.153241572421 19682.679752983873 26539.88152330061 20376.71467292973 22475.931092533316 22763.498458763926 0.5759207081747391 0.60885364091717 0.49542645630897086 0.6090511540223632 0.6629979688276763 0.8646597002055305 1.165896427184846 0.8951486393816902 0.9873671717573843 1.0 14.47443467802188 -6.793109605419869 2.453310460907471 1.0056697124316587 0.5743442902312516 0.8892600873539447 0.0709953777651589 0.08795206845938135 1.084692545320825 0.027220568184529247 0.024692285807533267 1.6102391984776216e-07 6.793109605419869 -0.43132542220040715 AT(ph)VSPGPHAGEAEPPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATVSPGPHAGEAEPPSR 17 0 O15055 O15055 PER2 Period circadian protein homolog 2 1 AT(0.897)VS(0.103)PGPHAGEAEPPSR 115.58 0.0009698 0.0 2805.5 3872.7 4176.2 5583.2 5048.8 4540.2 4749.4 4521.9 4358.1 2463.2 True False 3280.4157388492235 4257.156062217335 4275.776446326694 5270.391404978625 4059.523883114056 4302.10391943469 4299.502449321687 4403.204916349086 4421.828967784825 2909.7586613195303 1.1273841306693133 1.4630615654862527 1.4694608536323408 1.8112812842658863 1.3951410943727975 1.4785088456386803 1.4776147955074492 1.5132543378536762 1.519654886353906 1.0 11.506683783996253 -10.566162980067109 6.362531384054038 0.9999996059488979 1.4816002399440615 0.4504687576641725 0.15639707560322932 8.767544078123771e-07 1.3179890227845236e-07 0.15189135220511205 0.03683903385396933 2.715420047064077e-11 10.566162980067109 0.4816006339951636 AT(ph)VTPSPVKGK ddPTM_PC-9_AZD4547_30min_R2 1 ATVTPSPVKGK 11 1 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 AT(0.515)VT(0.329)PS(0.155)PVKGK 120.55 0.0088117 610350000.0 61432.0 45691.0 61899.0 79048.0 79066.0 60568.0 62850.0 66087.0 56900.0 58740.0 True False 80966.09813502098 60459.72221379638 61078.17881591188 60824.70487942562 68089.05067850405 56780.67338523021 68443.5282434169 55874.77267818194 59907.61783634773 56683.53047906447 1.4283884128375708 1.0666188521218982 1.0775295451730997 1.0730578064803258 1.201214005250645 1.0017137765651634 1.2074676306320735 0.9857320496086382 1.0568787323237399 1.0 15.790641997473978 -4.760112788839918 24.999950921946482 1.0799172309061196 1.4283888339686153 0.6792180175802991 0.07288057748812168 18.82532592374889 354634.7511715647 0.01707955461506877 0.10358285743923074 1.7373495702183898e-05 4.760112788839918 0.3484716030624957 ATAGDTHLGGEDFDNR ddPTM_PC-9_AZD4547_30min_R2 7 ATAGDTHLGGEDFDNR 16 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;P17066;P48741 A0A0G2JIW1;P17066 HSPA1B;HSPA1A;HSPA6;HSPA7 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7 0 ;;;;;; 193.28 4.9284999999999994e-11 475144300.0 942888.0 853411.2 1221636.2 1790252.0 1429996.2 1338112.0 1057544.1 1407034.8 1103346.8 1258207.4 False True 1242706.7707112513 1129259.6810343976 1205436.5057850867 1377537.0605176804 1231465.911161157 1254439.645107273 1151663.4761656146 1189609.902103153 1161667.4593208649 1214157.941894527 1.0235132743703654 0.9300764275134935 0.9928168850126435 1.1345616686147295 1.0142551217345113 1.0331766583430586 0.9485285533516352 0.9797818397884297 0.9567679947044139 1.0 20.211524673921723 -7.2554621056965 24.786369903605898 0.969584750112125 1.0207686466703354 0.20184154718011726 0.04878099115851767 788.5930085394012 3270117.5781425084 0.020515816481749334 0.015444695773978105 5.5531306876886624e-08 7.2554621056965 0.05118389655821043 ATAGDTHLGGEDFDNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 ATAGDTHLGGEDFDNR 16 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;P17066;P48741 A0A0G2JIW1;P17066 HSPA1B;HSPA1A;HSPA6;HSPA7 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7 0 ;;;;; 160.79 3.0498000000000002e-05 371455600.0 673440.9 637791.2 822805.0 828139.5 940101.0 880075.0 811045.0 766248.0 788084.0 600176.7 False True 787441.1433059283 701106.8953208022 842423.7917053372 781741.5286794842 755894.9576214941 833922.3177165083 734216.9461426928 746134.8019068665 799608.2375915509 708983.9847138559 1.1106613975543291 0.9888896088446443 1.1882127239380975 1.1026222672646027 1.0661664775496604 1.1762216576063804 1.0355903122960117 1.0524000795420005 1.1278227080323553 1.0 19.435393513135935 -11.044547897497342 3.2754633860924844 0.9974865819256774 1.0928195536806977 0.189599151261301 0.05840903455803632 6175864.774898867 6943836.528569288 97985.05600681502 0.013724354807126374 9.025101658835836e-12 11.044547897497342 0.09533297175502031 ATAGDTHLGGEDFDNR ddPTM_PC-9_Lapatinib_30min_R1 5 ATAGDTHLGGEDFDNR 16 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;P17066;P48741 A0A0G2JIW1;P17066 HSPA1B;HSPA1A;HSPA6;HSPA7 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7 0 ;;;; 159.41 2.6264e-05 417268000.0 963361.0 919355.0 1084449.0 808145.0 880431.0 950248.0 844396.0 838654.0 1001558.0 760059.0 False True 949623.2954812298 917226.289982504 995289.7893141948 867578.679192692 828645.7795739463 909608.1081762793 888114.69321864 877620.9264969499 888751.9911666967 891434.1854350418 1.0652758341523443 1.0289332683992538 1.1165039501244491 0.9732391839665565 0.9295647318815206 1.0203872849372142 0.9962762341060751 0.9845044545477569 0.9969911471736569 1.0 19.765768762077897 -5.7795224855441045 24.999877217397238 0.9847342278478847 1.066107250177185 0.6263280303103702 0.029809275093167557 153.62250343926587 212382.50490238718 0.008493534823277278 0.012626096931290283 1.6614126561011157e-06 5.7795224855441045 0.08137302232930044 ATAPAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 ATAPASPR 8 0 Q5T0Z8 Q5T0Z8 C6orf132 Uncharacterized protein C6orf132 1 AT(0.002)APAS(0.998)PR 76.17 0.025336 12049000.0 24147.0 26172.0 51198.0 68955.0 64469.0 56488.0 49628.0 62308.0 54258.0 45411.0 True False 31825.243711198553 34631.5871786452 50519.08106782108 53058.49009413014 55518.59216594332 52955.79643020878 54044.79585782488 52679.73029540093 57125.96711009758 43821.17471203265 0.7262526374597578 0.790293446175825 1.1528463442571584 1.2107957041955122 1.2669352779969802 1.2084522329262866 1.2333032195730933 1.202152398733753 1.303615603312698 1.0 15.419340538649566 -5.264727465397346 3.032766882029677 1.2152942984971509 0.731240374163269 0.8441619635635852 0.07583887409608349 0.08117606460092296 1.5046678626635543 0.01879453568613054 0.05498021445401609 5.435913465956725e-06 5.264727465397346 -0.48405392433388184 ATAPAS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATAPASPR 8 0 Q5T0Z8 Q5T0Z8 C6orf132 Uncharacterized protein C6orf132 1 AT(0.001)APAS(0.999)PR 83.99799999999999 0.036644 0.0 20360.0 30492.0 43775.0 44607.0 47664.0 35441.0 46910.0 50788.0 42271.0 40271.0 True False 23806.545871669994 33519.04424539233 44818.762017611996 42107.81440784523 38324.581358886906 33582.41156968525 42466.345201010685 49454.86881433409 42889.13340612475 47571.813514939386 0.5004338517427724 0.7045988321396672 0.9421285148933238 0.885142089330308 0.8056153114039158 0.7059308672169725 0.8926787116844854 1.0395834247269837 0.9015660795158861 1.0 15.53781940378064 -4.9466261299992995 2.7109521508181125 0.8870589756780912 0.4848514106172219 0.6612169180055139 0.08964576918876023 0.2206479407755473 2.792808073432857 0.02572216304144284 0.17061795163836238 1.1307689380084348e-05 4.9466261299992995 -0.4022075650608693 ATAPQTQHVS(ph)PMR ddPTM_PC-9_AZD4547_30min_R2 24 ATAPQTQHVSPMR 13 0 P29692-2;P29692;E9PRY8;A0A087X1X7;E9PK01;P29692-3;E9PI39;E9PQ49;P29692-4;E9PL71;E9PL12;E9PQZ1;E9PPR1;E9PK06 P29692-2 EEF1D Elongation factor 1-delta 1 ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQT(0.004)QHVS(0.996)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQT(0.001)QHVS(0.999)PMR;ATAPQTQHVS(1)PMR;ATAPQT(0.002)QHVS(0.998)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQT(0.001)QHVS(0.999)PMR;AT(0.006)APQT(0.011)QHVS(0.983)PMR;ATAPQTQHVS(1)PMR;ATAPQT(0.002)QHVS(0.998)PMR 156.72 5.1719e-05 10078143100.0 8891045.0 8797239.5 12171631.6 16752030.0 15257372.2 13558259.7 10501323.100000001 13966955.8 10732782.5 12557494.1 True False 11718212.364775497 11640775.128980255 12010227.812181192 12890108.29978348 13139149.431444598 12710459.57762895 11435920.51214154 11808683.709825134 11300095.471540248 12117860.05376275 0.9670199451706691 0.9606296059976073 0.9911178837596711 1.0637281040212159 1.0842796808306698 1.0489029846224531 0.9437244250556055 0.9744858958127995 0.9325157594992545 1.0 23.530631613648865 -9.874067597322233 6.931054583351882 1.000000005774245 0.9990023951612792 0.0 0.049584675741398354 0.0 0.0 0.054135696311628456 0.013129834941717915 1.3363874935332344e-10 9.874067597322233 -0.0009976106129658824 ATAPQTQHVS(ph)PMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 24 ATAPQTQHVSPMR 13 0 P29692-2;P29692;E9PRY8;A0A087X1X7;E9PK01;P29692-3;E9PI39;E9PQ49;P29692-4;E9PL71;E9PL12;E9PQZ1;E9PPR1;E9PK06 P29692-2 EEF1D Elongation factor 1-delta 1 ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQT(0.007)QHVS(0.993)PMR;ATAPQT(0.004)QHVS(0.996)PMR;ATAPQTQHVS(1)PMR;ATAPQT(0.002)QHVS(0.998)PMR;ATAPQTQHVS(1)PMR;ATAPQT(0.005)QHVS(0.995)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;AT(0.001)APQT(0.02)QHVS(0.98)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQT(0.003)QHVS(0.997)PMR 140.03 2.7978000000000002e-05 19018697000.0 12255400.3 12528821.3 14585648.2 15186742.7 16874836.0 14773118.8 15520166.3 13875987.3 13092857.1 10487376.5 True False 14329997.515600607 13772599.878568593 14933425.369466813 14335878.742603129 13568333.022823796 13998390.4435387 14049983.791790538 13511757.336198837 13284315.365835363 12388654.841423314 1.156703265933774 1.111710678427964 1.2054113671433222 1.1571779927768253 1.0952224592984907 1.1299362701374966 1.1341008343224095 1.0906557256741274 1.0722968341500059 1.0 23.56251621254865 -8.513861930877367 0.4665343500073163 0.9935094886766339 1.1555422879106456 0.7447346949604998 0.026888166768986293 0.6029198850556072 0.33001256637166027 0.03576629769615946 0.01779491339563429 3.0629370353159428e-09 8.513861930877367 0.1620327992340117 ATAPQTQHVS(ph)PMR ddPTM_PC-9_Lapatinib_30min_R1 33 ATAPQTQHVSPMR 13 0 P29692-2;P29692;E9PRY8;A0A087X1X7;E9PK01;P29692-3;E9PI39;E9PQ49;P29692-4;E9PL71;E9PL12;E9PQZ1;E9PPR1;E9PK06 P29692-2 EEF1D Elongation factor 1-delta 1 ATAPQTQHVS(1)PMR;ATAPQT(0.001)QHVS(0.999)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQT(0.002)QHVS(0.998)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQT(0.001)QHVS(0.999)PMR;ATAPQTQHVS(1)PMR;ATAPQT(0.001)QHVS(0.999)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQT(0.002)QHVS(0.998)PMR;ATAPQT(0.018)QHVS(0.982)PMR;ATAPQTQHVS(1)PMR;ATAPQT(0.003)QHVS(0.997)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQT(0.001)QHVS(0.999)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQT(0.002)QHVS(0.998)PMR;ATAPQT(0.001)QHVS(0.999)PMR;ATAPQTQHVS(1)PMR;AT(0.001)APQT(0.004)QHVS(0.995)PMR;ATAPQTQHVS(1)PMR;ATAPQT(0.409)QHVS(0.59)PMR;ATAPQT(0.001)QHVS(0.999)PMR 153.92 7.7815e-05 12582060100.0 11642874.7 10826997.899999999 12071306.7 10849369.6 11201324.1 11106126.200000001 9338959.1 9566774.9 11434670.799999999 8755142.300000003 True False 11476845.171736287 10801928.651571313 11078850.459717395 11647268.43282 10542484.239088481 10631143.072070662 9822484.706320189 10011282.187082816 10146777.762082346 10268456.981061177 1.1176796273192577 1.0519524668111337 1.0789206674528493 1.1342764014400468 1.026686313097743 1.0353204080884217 0.9565687156732968 0.97495487448088 0.9881501944057172 1.0 23.29171607147439 -6.744636362260007 1.7729548009837517 0.9796221324113241 1.0901924791740933 0.7593874444313672 0.02780579968793164 0.16747369052911318 1.0883056092266445 0.011396859970971188 0.01054202838601964 1.800377752803859e-07 6.744636362260007 0.11057034676276922 ATAPQTQHVS(ph)PMRQVEPPAK ddPTM_PC-9_AZD4547_30min_R2 2 ATAPQTQHVSPMRQVEPPAK 20 1 P29692-2;P29692;E9PRY8;A0A087X1X7;E9PK01;P29692-3;E9PI39;E9PQ49;P29692-4;E9PL71;E9PL12;E9PQZ1;E9PPR1;E9PK06 P29692-2 EEF1D Elongation factor 1-delta 1 ATAPQT(0.001)QHVS(0.999)PMRQVEPPAK;ATAPQT(0.037)QHVS(0.963)PMRQVEPPAK 74.876 0.0037044000000000005 25196000.0 72087.0 31724.4 94078.0 438650.0 247013.0 92312.0 61439.0 82986.0 69245.0 123771.0 True False 95009.16649725316 41978.69189554531 92830.46425052668 337526.0195749422 212719.50870474416 86539.71604704436 66906.95197688595 70162.42052857003 72905.14933353073 119437.81496296021 0.7954697306436591 0.35146902100112637 0.7772284203232875 2.8259560816615323 1.7810063652848327 0.7245587678733227 0.5601823174480794 0.5874389158101112 0.610402571046196 1.0 16.86590015209712 -6.891852097619521 8.68450133605533 0.6536421259538692 1.3072790608483005 0.18322173179695966 0.6420765671184903 0.5090584421077419 37.55787943133881 0.2571967594645619 0.22687922908659106 1.2827673647298484e-07 6.891852097619521 0.6536369348944313 ATAPQTQHVS(ph)PMRQVEPPAK ddPTM_PC-9_Lapatinib_30min_R1 2 ATAPQTQHVSPMRQVEPPAK 20 1 P29692-2;P29692;E9PRY8;A0A087X1X7;E9PK01;P29692-3;E9PI39;E9PQ49;P29692-4;E9PL71;E9PL12;E9PQZ1;E9PPR1;E9PK06 P29692-2 EEF1D Elongation factor 1-delta 1 ATAPQT(0.005)QHVS(0.995)PMRQVEPPAK;ATAPQT(0.013)QHVS(0.986)PMRQVEPPAK 58.5 0.026022000000000003 26620000.0 340860.0 32243.0 81041.0 44127.0 30987.4 34767.0 17327.4 18923.7 56433.0 25207.0 True False 335999.2738939309 32168.343314503996 74378.12180730648 47372.24678335679 29164.782055572417 33280.09645583542 18224.52798838066 19802.9641863633 50076.92127416504 29563.99636378378 11.365150697472474 1.088091843831728 2.5158344931479055 1.602362759095327 0.986496605421708 1.1256968119710602 0.6164433172068006 0.6698338053722044 1.6938481745827103 1.0 14.851553680985878 -4.76083810608548 24.999999936472456 1.2628897228369256 11.365162236314838 0.9700981290157205 0.5324781746634685 2.3777086040531237 98780.90359993937 0.14388851377304593 0.830852405083365 1.734450436177554e-05 4.76083810608548 10.102272513477912 ATAPQTQHVSPMR ddPTM_PC-9_AZD4547_30min_R2 4 ATAPQTQHVSPMR 13 0 P29692-2;P29692;E9PRY8;A0A087X1X7;E9PK01;P29692-3;E9PI39;E9PQ49;P29692-4;E9PL71;E9PL12;E9PQZ1;E9PPR1;E9PK06 P29692-2 EEF1D Elongation factor 1-delta 0 ;;; 99.669 0.0016614000000000002 9712200.0 40697.7 40346.8 56666.0 79706.0 60603.0 53660.0 48528.7 64897.0 45492.8 61343.8 False True 53638.72203525264 53388.11407532335 55914.57181509334 61331.01314542429 52189.31953392581 50304.631717267424 52847.66028745112 54868.659834702325 47897.4565326081 59196.17223359956 0.9061180818175854 0.9018845655196001 0.9445639761037861 1.0360638337120893 0.8816333483181421 0.8497953468808018 0.8927546882407197 0.9268954015840749 0.8091309746109168 1.0 15.853216270299919 ATAPQTQHVSPMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATAPQTQHVSPMR 13 0 P29692-2;P29692;E9PRY8;A0A087X1X7;E9PK01;P29692-3;E9PI39;E9PQ49;P29692-4;E9PL71;E9PL12;E9PQZ1;E9PPR1;E9PK06 P29692-2 EEF1D Elongation factor 1-delta 0 ; 75.483 0.012424 10589700.0 24130.0 38109.0 31237.0 36324.0 44195.0 31097.0 30941.0 30288.0 31925.0 25854.0 False True 28214.7324107759 41892.20966639306 31981.808546982185 34288.88404399692 35535.30700646205 29466.218576860167 28010.04448655879 29492.972092788685 32391.8427288338 30541.125539848625 0.9238275247571556 1.3716655468945986 1.0471719028577982 1.122711865980787 1.1635231635486796 0.964804605462691 0.9171254821637991 0.9656805887624423 1.0605975436815662 1.0 14.898465610670337 -6.765378829658556 24.943345837992467 0.9754643954840279 1.1349027488776138 0.2983264658737149 0.10988005479475754 112.57206990595567 712765.4298305842 0.036134563254462855 0.0330482157961739 1.7164105304789289e-07 6.765378829658556 0.15943835339358592 ATAPQTQHVSPMR ddPTM_PC-9_Lapatinib_30min_R1 3 ATAPQTQHVSPMR 13 0 P29692-2;P29692;E9PRY8;A0A087X1X7;E9PK01;P29692-3;E9PI39;E9PQ49;P29692-4;E9PL71;E9PL12;E9PQZ1;E9PPR1;E9PK06 P29692-2 EEF1D Elongation factor 1-delta 0 ;; 78.28699999999999 0.010291 10816900.0 65099.0 123841.0 77069.0 90280.0 72053.0 74649.0 60444.0 61457.0 72898.0 69751.0 False True 64170.67632230551 123554.25377326833 70732.6843149431 96919.49236525135 67814.98420164839 71456.43628531822 63573.49456523657 64312.5165798089 64687.45959002861 81807.36741263465 0.7844119466481542 1.510307172580964 0.864624868786804 1.1847281660634728 0.8289593754996544 0.8734718955677117 0.7771120936403344 0.7861457789665559 0.7907290215531129 1.0 16.319943154880868 -6.273178475273913 23.447725945689317 0.8302991741996478 1.1005106024489886 0.2762072237638159 0.19172754611721127 372.72068122175097 744472.2082451364 0.0552751508186723 0.06326212878837754 5.331157641391416e-07 6.273178475273913 0.27021142824934075 ATAS(ph)GIMGSPKPAIK ddPTM_PC-9_AZD4547_30min_R2 1 ATASGIMGSPKPAIK 15 1 Q5T670;Q7L590-2;Q7L590 Q5T670 MCM10 Protein MCM10 homolog 1 AT(0.393)AS(0.592)GIMGS(0.015)PKPAIK 75.669 0.02244 7191600.0 21820.0 19755.0 26098.0 36958.0 27925.0 23287.0 26013.0 23183.0 20156.0 22110.0 True False 28758.306115805382 26140.417419919595 25751.923467869718 28437.904095408034 24048.09577058691 21830.860208721704 28328.106606141664 19600.60004234255 21221.405010710456 21335.93562976023 1.3478811810667504 1.2251826155426657 1.206974182653133 1.3328641681755773 1.1271170005332998 1.023196760036674 1.327718038604713 0.9186660656682352 0.994632032030973 1.0 14.380997756965353 -7.05367435881614 0.5125389261202763 0.9646897754911695 1.3008813176820286 0.5112802975745716 0.10598319594516023 0.821256795797732 0.46210788770180183 0.09976386162633198 0.10174169316706971 8.837422966369546e-08 7.05367435881614 0.3361915421908591 ATAS(ph)SPTQQDGR ddPTM_PC-9_AZD4547_30min_R2 2 ATASSPTQQDGR 12 0 Q9BV73-2;Q9BV73 Q9BV73-2 CEP250 Centrosome-associated protein CEP250 1 AT(0.002)AS(0.603)S(0.394)PT(0.002)QQDGR;AT(0.004)AS(0.497)S(0.497)PT(0.001)QQDGR 150.9 0.00018072 9779600.0 21440.0 22287.0 24313.0 38238.0 34568.0 31462.0 23421.0 38444.0 26914.0 28137.0 True False 28257.474020296402 29490.836903960946 23990.59373416801 29422.819871210893 29768.82988711362 29494.676166393354 25505.423627511 32503.363155235187 28336.619093979993 27151.932194236273 1.0407168748857885 1.0861413726652267 0.8835685638335772 1.083636319534441 1.096379796257478 1.0862827718999088 0.9393594328776798 1.197092086217529 1.0436317714433303 1.0 14.728767246745035 ATAS(ph)SPTQQDGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATASSPTQQDGR 12 0 Q9BV73-2;Q9BV73 Q9BV73-2 CEP250 Centrosome-associated protein CEP250 1 ATAS(0.599)S(0.382)PT(0.019)QQDGR 145.52 0.00011111 3790000.0 8982.7 13032.0 13238.0 13114.0 15400.0 13691.0 13585.0 12393.0 9625.2 8087.3 True False 10503.293693587924 14325.730834512431 13553.644125394569 12379.265096161644 12382.480549824988 12973.01985837196 12298.13045311726 12067.69688146891 9765.95034091061 9553.463470968423 1.0994226047449593 1.499532695974212 1.4187152299877535 1.2957881854869093 1.2961247601410246 1.3579389189894395 1.287295491367029 1.2631750692448738 1.0222418676313467 1.0 13.221808141007767 -8.201172146035146 2.2294428733909193 0.9886650695491269 1.332640851889162 0.6111738616607687 0.09761366022736791 0.19911450081196744 1.7721406264047528 0.08707240857409704 0.025898906628108776 6.292567080802244e-09 8.201172146035146 0.343975782340035 ATAS(ph)SPTQQDGR ddPTM_PC-9_Lapatinib_30min_R1 1 ATASSPTQQDGR 12 0 Q9BV73-2;Q9BV73 Q9BV73-2 CEP250 Centrosome-associated protein CEP250 1 ATAS(0.61)S(0.387)PT(0.003)QQDGR 129.76 0.00016585 4239100.0 13533.0 14986.0 19409.0 11633.0 13735.0 12397.0 13867.0 14080.0 11740.0 10636.0 True False 13340.016938351746 14951.300837737104 17813.26694090663 12488.529626550397 12927.134304048963 11866.809208818466 14584.965408247888 14734.208201567102 10417.717572319336 12474.418428420842 1.0693898889874325 1.19855694464065 1.427983760775743 1.0011312109025783 1.0362915416238312 0.9512915793959547 1.1691900100944606 1.1811539180053245 0.8351265136805366 1.0 13.606684936595661 -5.805573373851056 24.99999826053415 1.0358532518677668 1.228636040804155 0.3655008203052428 0.12442987418683765 148.672057582291 84215.58240746225 0.03547331818190018 0.05261575290496982 1.5646839442666526e-06 5.805573373851056 0.19278278893638823 ATASS(ph)PTQQDGR ddPTM_PC-9_Lapatinib_30min_R1 1 ATASSPTQQDGR 12 0 Q9BV73-2;Q9BV73 Q9BV73-2 CEP250 Centrosome-associated protein CEP250 1 ATAS(0.222)S(0.749)PT(0.029)QQDGR 81.185 0.013479 3731600.0 8863.4 9460.8 10739.0 9020.1 10648.0 9945.3 8190.5 8242.6 9490.6 7456.8 True False 8737.00629065151 9438.894098869823 9856.08087373879 9683.468244171518 10021.705574773452 9519.962702626624 8614.564013575711 8625.581287090696 8421.668687551439 8745.697944438562 0.9990061795133711 1.0792613875799437 1.126963329439742 1.1072264678806212 1.1459011777494912 1.0885309283612319 0.9850058929892223 0.986265629328732 0.9629498687302396 1.0 13.094357806693628 -7.2548646120873865 5.425492185227723 0.9817457369415811 1.0959079986922604 0.664575333302563 0.03738370586385725 0.10759856462013627 11.44466425519558 0.016089034009021654 0.01162805630685486 5.560775830957195e-08 7.2548646120873865 0.11416226175067934 ATAVMPDGQFK ddPTM_PC-9_AZD4547_30min_R2 1 ATAVMPDGQFK 11 0 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 132.78 0.00083933 0.0 21710.0 16329.0 26804.0 35663.0 32958.0 30327.0 24591.0 34853.0 24274.0 33377.0 False True 28613.328403947497 21607.02991900113 26448.56144657752 27441.44633785745 28382.35059649071 28430.647895817536 26779.551360920676 29467.269692264366 25557.074083646814 32208.48138916812 0.8883786869122712 0.6708490741282724 0.8211676026263167 0.8519944174420515 0.8812073519875993 0.8827068731461183 0.8314440857160927 0.9148916192669165 0.7934889501571407 1.0 14.975153019656547 -14.52287874509517 0.07711063215845035 1.5101048847460985 0.6737494109957952 0.365001802285029 0.06501440506142295 279.3437023554762 1.5271432288821298 24.844937253275283 2.5060298467862108 3.0000000012790924e-15 14.52287874509517 -0.8363554737503033 ATAVMPDGQFK ddPTM_PC-9_Lapatinib_30min_R1 2 ATAVMPDGQFK 11 0 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 ; 154.84 0.00055195 48070000.0 237150.0 240260.0 239530.0 214240.0 247550.0 224620.0 228100.0 207530.0 225000.0 208698.0 False True 233768.19751201596 239703.69273152982 219836.7680125387 229995.9242836895 232989.5957020255 215013.52621479437 239909.9018981285 217172.6014255125 199658.13064496184 244771.17122739548 0.9550479181833157 0.9792970778770433 0.8981317812476682 0.9396364904019698 0.9518669806321891 0.8784266755623934 0.9801395347953342 0.8872474660169699 0.815692998663952 1.0 17.901074124066866 -4.905843152357623 0.5405732431121825 0.9101161105608754 0.9994776361659401 0.07959817465491859 0.0521875696612364 9.027608344231023 2.218181240270864 0.030700023754988183 0.5018027496574321 1.2421008175711539e-05 4.905843152357623 0.08936152560506472 ATCAPQHGAPGPGPADASK ddPTM_PC-9_AZD4547_30min_R2 1 ATCAPQHGAPGPGPADASK 19 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 78.917 0.0024767 2228300.0 11119.0 13465.0 13779.0 20666.0 13891.0 16305.0 11794.0 16792.0 14351.0 15658.0 False True 14654.610710432631 17817.297927573658 13596.281456961338 15901.772986517179 11962.474426113618 15285.445772457057 12843.643151994565 14197.182241772682 15109.564561852829 15109.818185924274 0.9698733982176108 1.1791867849324333 0.8998309105815125 1.0524132581112497 0.7917020760221589 1.0116234083277316 0.8500197020212467 0.9395998063694924 0.9999832146179176 1.0 13.883198680433162 -5.2798995985885915 24.89588072046381 0.938602688993517 1.0745301114558794 0.25871995136887693 0.08868997121287253 817.5655063838554 1102586.8843147133 0.02155891851853319 0.045016195352309614 5.249288007297135e-06 5.2798995985885915 0.13592742246236245 ATCAPQHGAPGPGPADASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ATCAPQHGAPGPGPADASK 19 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ;; 116.73 5.5463e-05 7693000.0 47546.6 46033.1 48562.0 56215.0 59061.0 51458.0 56180.0 53282.0 47377.0 44603.0 False True 55595.30029184402 50602.96194584057 49719.90225241056 53065.45580148901 47488.42102293595 48759.451893368205 50858.22369202264 51883.403956945505 48069.79899652184 52689.170822846245 1.0551561055832304 0.9604053576014697 0.9436455627586343 1.0071415999296691 0.9012937626709581 0.925416952514005 0.965250029517836 0.9847071636672757 0.9123278701451603 1.0 15.685218855537544 -4.762243087681795 5.007545400838822 0.9535674151013303 1.0615751159614588 0.4381509700198988 0.033848021032830335 0.15962669355789189 10.570886006773796 0.008260891139320582 0.06081353931445127 1.728848399902374e-05 4.762243087681795 0.10800770086012856 ATCAPQHGAPGPGPADASK ddPTM_PC-9_Lapatinib_30min_R1 4 ATCAPQHGAPGPGPADASK 19 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ;;; 119.38 4.2365e-05 27596400.0 90620.0 82552.0 96189.0 85584.0 89925.0 78762.0 92761.0 73108.0 90103.0 82304.0 False True 89327.74218232716 82360.85591597972 88280.71172027766 91878.13285985481 84635.78829935219 75393.53286318955 97563.71069694126 76504.86457387537 79954.65131334656 96530.13673681379 0.9253870884475828 0.8532139153654558 0.9145404192368658 0.9518077562695005 0.8767809842651405 0.7810362174120556 1.0107072671299064 0.7925490127758064 0.8282869372840553 1.0 16.558691802065944 -6.488601217040481 24.274439366902563 0.8721562050618378 0.9081994219066597 0.02660030644905076 0.07574022673356812 1557.6096838803758 1103058.9153160767 0.022909925418880067 0.025959930911149766 3.2463757304213937e-07 6.488601217040481 0.036043216844821924 ATDEDMQS(ph)LASLMSMK ddPTM_PC-9_AZD4547_30min_R2 1 ATDEDMQSLASLMSMK 16 0 Q8NDI1-3;Q8NDI1-2;Q8NDI1;C9K0H9;B5MC86 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 ATDEDMQS(0.994)LAS(0.005)LMS(0.001)MK 61.435 0.025917000000000003 3694700.0 20908.0 24484.0 22153.0 29151.0 27431.0 29522.0 20371.0 28994.0 20501.0 19032.0 True False 27556.309086583824 32397.974189284338 21859.23674548693 22430.687328460375 23622.67914352621 27675.984673074352 22183.97953614392 24513.64351583832 21584.641006379003 18365.69547288996 1.5004228468919323 1.7640483169890169 1.1902210170997267 1.22133612427424 1.2862392920756096 1.506939103609092 1.2079030477713313 1.3347517142502714 1.175269460295724 1.0 14.1647259086869 -1.5228787452803418 0.10610058110733203 0.8958583960542359 2.858896655582782 0.46802770106899505 0.1509816148952864 115.2792158978995 0.8622629042240543 1.675058130532187 33.03307291996894 0.029999999999999704 1.5228787452803418 1.963038259528546 ATDFVVPGPGK ddPTM_PC-9_Lapatinib_30min_R1 2 ATDFVVPGPGK 11 0 O75874;C9J4N6 O75874 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic 0 ; 128.27 0.001467 7859800.0 92443.0 93883.0 101719.0 94177.0 91056.0 85028.0 88719.0 78812.0 92515.0 95289.0 False True 91124.74586803003 93665.61968165438 93356.05646669507 101103.09074526251 85700.26510298387 81391.55064994891 93312.43571459902 82473.89323735128 82094.98647386064 111759.57668538837 0.8153640929094879 0.8380992704126838 0.8353293671601799 0.9046481182536628 0.7668270375096049 0.7282736125519897 0.8349390583080013 0.7379581748911013 0.7345678008871152 1.0 16.77003893577421 -6.288141858390922 24.781649757731955 0.7854433921777317 0.8466965292554227 0.06331117678879972 0.07841283083520544 1389.080434509171 1289153.0935823026 0.02295300900502603 0.02603405628929776 5.150603772566884e-07 6.288141858390922 0.06125313707769098 ATDHPHPS(ph)TPATAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATDHPHPSTPATAR 14 0 H7BYJ3;O14578;O14578-4;O14578-3 H7BYJ3 CIT Citron Rho-interacting kinase 1 ATDHPHPS(0.499)T(0.499)PAT(0.002)AR 71.781 0.039606 0.0 3318.1 4425.6 12853.0 7157.4 12218.0 10858.0 7120.7 7669.4 8652.2 6072.2 True False 3879.7887945377333 4864.944320228528 13159.46426527395 6756.394082603882 9823.970607646872 10288.587365583424 6446.175746596393 7468.086376400996 8778.722056645758 7173.041792491246 0.54088473297327 0.6782261223294643 1.8345723677574697 0.9419147800974043 1.369568293597651 1.4343409202430044 0.8986669718478794 1.0411324222617249 1.2238492832755192 1.0 12.808369321071181 -5.029278833370684 24.468042652354637 1.214351975843264 0.5752197198804215 0.4588245864607239 0.26613163967156717 378.5597601513717 316360.1041578104 0.06579094380180261 0.17479968912462737 9.34805301319901e-06 5.029278833370684 -0.6391322559628424 ATDIPASAS(ph)PPPVAGVPFFK ddPTM_PC-9_AZD4547_30min_R2 2 ATDIPASASPPPVAGVPFFK 20 0 Q8N1G0;Q8N1G0-2;F8WCX2 Q8N1G0 ZNF687 Zinc finger protein 687 1 ATDIPAS(0.001)AS(0.999)PPPVAGVPFFK;ATDIPAS(0.044)AS(0.956)PPPVAGVPFFK 165.16 4.9616e-08 130434000.0 415860.0 516570.0 602240.0 582190.0 625770.0 619780.0 534090.0 653390.0 524040.0 536990.0 True False 548094.8295746478 683541.1504230762 594253.904103374 447975.09024583554 538892.6370764599 581025.0586233315 581622.9753305719 552423.5889085204 551739.6845511362 518190.1435470362 1.0577098704018424 1.3190933076113809 1.1467873549961365 0.8644994425780173 1.0399515386142124 1.1212584142303195 1.1224122700392078 1.0660634822714972 1.0647436880494325 1.0 18.983122048829678 -5.5341393720823016 24.944897703251776 1.046067645980237 1.1995363176870286 0.3214142494609218 0.09042457825221538 223.46325803450233 495021.04759354086 0.024764805680671485 0.04293886285437101 2.923214120886509e-06 5.5341393720823016 0.15346867170679168 ATDIPASAS(ph)PPPVAGVPFFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ATDIPASASPPPVAGVPFFK 20 0 Q8N1G0;Q8N1G0-2;F8WCX2 Q8N1G0 ZNF687 Zinc finger protein 687 1 ATDIPASAS(1)PPPVAGVPFFK;ATDIPAS(0.048)AS(0.952)PPPVAGVPFFK;ATDIPAS(0.027)AS(0.973)PPPVAGVPFFK 176.28 2.36e-09 101838400.0 484553.0 577712.0 519896.0 550951.0 608923.0 459157.0 508648.0 382278.3 416974.0 402337.1 True False 566578.2525420109 635063.4293944007 532292.292356559 520083.0016772409 489608.9093403297 435077.99862029805 460465.1791473826 372243.8996823396 423071.4559126934 475277.6313312685 1.1920995544330715 1.336194652408881 1.11996074981604 1.0942719947085897 1.0301534872763078 0.9154186310044301 0.9688341061993687 0.7832135895806246 0.8901564643967277 1.0 18.858410978061386 -6.070103443861338 0.8590087341679223 0.8871576208424808 1.277396122230447 0.78830256260089 0.06983815774387761 0.2761547824118941 0.41874679407469667 0.03284723795564642 0.06970372824075888 8.509353312280544e-07 6.070103443861338 0.39023850138796623 ATDIPASAS(ph)PPPVAGVPFFK ddPTM_PC-9_Lapatinib_30min_R1 2 ATDIPASASPPPVAGVPFFK 20 0 Q8N1G0;Q8N1G0-2;F8WCX2 Q8N1G0 ZNF687 Zinc finger protein 687 1 ATDIPAS(0.013)AS(0.987)PPPVAGVPFFK;ATDIPAS(0.001)AS(0.999)PPPVAGVPFFK 172.93 5.1267e-09 77707000.0 274530.0 371130.0 408510.0 319260.0 418000.0 392110.0 376890.0 398580.0 413890.0 323190.0 True False 270615.1518573642 370270.6712871591 374923.88469420216 342739.4454201397 393414.0618196194 375340.36935305427 396403.5200630666 417099.48188782815 367273.3497450809 379052.96087639354 0.7139243846867348 0.9768309695591633 0.9891068620789963 0.9041993620830853 1.0378867926793716 0.990205612654349 1.0457734432322003 1.1003725730659608 0.9689235744153603 1.0 18.532039908732322 -4.273629462200041 1.5430566383497988 1.0100450271931714 2.434881828403268e-14 0.7504617535227094 0.049677978945152426 2.355362260900029 1.7934667336806862 0.014521871201134165 5.329880023531875 5.325624450012995e-05 4.273629462200041 -1.010045027193147 ATDS(ph)FSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATDSFSGR 8 0 Q9HBH9;K7EK27;Q9HBH9-2 Q9HBH9 MKNK2 MAP kinase-interacting serine/threonine-protein kinase 2 1 AT(0.001)DS(0.837)FS(0.162)GR;AT(0.025)DS(0.974)FS(0.001)GR 90.149 0.009692000000000001 8755100.0 35371.0 34999.0 44559.0 45761.0 48682.0 37565.0 46242.0 38870.0 36136.0 33758.0 True False 41358.6116909057 38473.46941966701 45621.45555094853 43197.15952916374 39143.11156666107 35595.025270596925 41861.622996911894 37849.7036861693 36664.42063740447 39878.05817181906 1.037127021398773 0.9647779050298733 1.1440239982193567 1.08323126825895 0.9815701506329273 0.8925967537644834 1.0497407576002429 0.9491360768643656 0.9194133896748866 1.0 15.283307540185927 -6.374262648580521 5.392813987088569 0.9619269104214143 1.0564531136411155 0.3813965597943204 0.05762156627337361 0.2567219679356321 10.528979794306684 0.018618715638659945 0.02114847938320056 4.2241307394870127e-07 6.374262648580521 0.09452620321970118 ATDS(ph)FSGR ddPTM_PC-9_Lapatinib_30min_R1 1 ATDSFSGR 8 0 Q9HBH9;K7EK27;Q9HBH9-2 Q9HBH9 MKNK2 MAP kinase-interacting serine/threonine-protein kinase 2 1 ATDS(1)FSGR 123.86 0.0032984999999999998 6128100.0 18966.0 20976.0 25793.0 19148.0 23668.0 21985.0 23106.0 27575.0 32221.0 21537.0 True False 18695.541362061558 20927.43136076161 23672.39910385927 20556.2077958555 22275.894773078337 21044.752799538106 24302.315621473692 28856.23516748671 28591.931677828048 25259.641753751388 0.7401348579809144 0.8284928014726738 0.9371628994042881 0.8137964899206312 0.8818769082411897 0.8331374215318269 0.9621005657320726 1.1423849731836035 1.1319215037395283 1.0 14.624546557718805 -7.5274950587941225 3.19462858246524 1.1019459926929385 0.844593125584279 0.7793044117026777 0.06003873578911842 0.11115865502462023 2.3522816007588925 0.030453946356305262 0.01729406974904894 2.9682805150221766e-08 7.5274950587941225 -0.25735286710865946 ATDS(ph)LPGKFEDMYK ddPTM_PC-9_Lapatinib_30min_R1 1 ATDSLPGKFEDMYK 14 1 A0A499FJN1;A0A499FIS5;Q9BUB5-2;Q9BUB5;E9PN34;E9PSE0;E9PLE7;E9PMM8;E9PII5;E9PIA0;A0A499FJS1;Q9BUB5-3 A0A499FJN1 MKNK1 MAP kinase-interacting serine/threonine-protein kinase 1 1 AT(0.018)DS(0.982)LPGKFEDMYK 56.339 0.033629 2884300.0 16280.0 19247.0 20115.0 17319.0 24064.0 23654.0 19250.0 17621.0 21604.0 15030.0 True False 16047.84421461364 19202.434754032165 18461.222346145427 18592.697034490342 22648.6028316443 22642.373560167147 20246.67080902662 18439.735988623135 19170.730019794468 17627.915473783876 0.9103653939389426 1.089319652263474 1.0472720029546794 1.0547303260071381 1.2848145809030658 1.2844612055146702 1.1485572890984947 1.0460531204637664 1.0875210996050586 1.0 14.10557426354172 -3.8458581440171455 0.882579701788786 1.1400438531353754 0.043882471118006555 0.3117492593384418 0.09248969478158875 12.577234955319424 2.2398526701905563 0.034356680399589605 19.69048886202346 0.00014260733236684986 3.8458581440171455 -1.0961613820173688 ATDSDLSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 ATDSDLSSPR 10 0 Q9BRD0;Q9BRD0-2 Q9BRD0 BUD13 BUD13 homolog 1 ATDSDLS(0.185)S(0.815)PR;ATDSDLS(0.158)S(0.842)PR 112.83 0.0013942 42235000.0 136759.0 134034.0 184006.0 239159.0 214237.0 189499.0 161433.0 198721.0 145009.0 179213.0 True False 180245.51723608727 177357.86932227295 181565.96021261555 184024.5875197167 184493.89054980245 177649.59757343406 175800.22426284067 168013.2356042946 152673.87969825903 172938.80741819178 1.0422502613900118 1.0255527488020386 1.0498855804733407 1.0641023276789336 1.066816021829437 1.0272396359473608 1.0165458342599158 0.9715184122787062 0.8828202413184848 1.0 17.399902120094517 -7.717737830163196 2.16143753516497 0.9384140725667438 1.0465193582096126 0.6762585433435708 0.029513236414604224 0.17196456395944154 1.5943004442174535 0.019025405878820047 0.008334832063718347 1.9154118496146947e-08 7.717737830163196 0.10810528564286881 ATDSDLSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATDSDLSSPR 10 0 Q9BRD0;Q9BRD0-2 Q9BRD0 BUD13 BUD13 homolog 1 ATDSDLS(0.115)S(0.885)PR 113.67 0.0012735 11968000.0 85042.0 77832.0 94323.0 88832.0 109350.0 97913.0 90622.0 95546.0 79811.0 77886.0 True False 99437.93094393714 85558.64658623186 96572.01804196926 83855.03103722975 87923.65247554294 92778.26991401451 82037.62811353644 93038.01873935532 80978.08488742237 92006.11525476322 1.0807752361741974 0.9299234768180523 1.049626079468339 0.9114071472862073 0.9556283539641249 1.0083924275806364 0.891654080670353 1.0112155967213132 0.880138071944409 1.0 16.489442133703 -4.752336691323682 24.998086215793204 0.9606837306376144 1.0807754683601714 0.31275007155491386 0.05379473198006784 421.83879906804697 1158383.410038287 0.012304775676979275 0.14854653940958812 1.768737194703628e-05 4.752336691323682 0.12009173772255699 ATDSDLSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 ATDSDLSSPR 10 0 Q9BRD0;Q9BRD0-2 Q9BRD0 BUD13 BUD13 homolog 1 ATDSDLS(0.351)S(0.649)PR;ATDSDLS(0.13)S(0.87)PR 104.43 0.0026051 40337000.0 117402.0 110880.0 116292.0 100641.0 118667.0 106111.0 95261.0 94798.0 127618.0 87545.0 True False 115727.8259511098 110623.26417244702 106730.92066010188 108042.4748685342 111687.24036829847 101572.87988682243 100193.14846434718 99202.66115711373 113244.31696288336 102677.03660361982 1.1271052396834549 1.077390503579717 1.0394818957634304 1.0522554842094578 1.0877528614256968 0.9892463129700563 0.9758087278184548 0.966162098542844 1.1029176601586006 1.0 16.647754037958336 -6.761848751901332 24.999908675982915 1.002773445515647 1.0733936625488925 0.4159269135534279 0.04122008661475579 11.429092444045125 697931.040266606 0.014274492443725612 0.013369923951440514 1.730418892771623e-07 6.761848751901332 0.0706202170332455 ATDSFS(ph)GR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATDSFSGR 8 0 Q9HBH9;K7EK27;Q9HBH9-2 Q9HBH9 MKNK2 MAP kinase-interacting serine/threonine-protein kinase 2 1 AT(0.001)DS(0.114)FS(0.885)GR 77.533 0.023407 3339300.0 18041.0 22650.0 25978.0 22001.0 30448.0 30580.0 27120.0 20706.0 25620.0 20100.0 True False 21094.98497400778 24898.542311364836 26597.414042113625 20768.35529820439 24481.932972796847 28976.33096698666 24550.99726820315 20162.489439820467 25994.644031721895 23743.970888487547 0.8884354294856321 1.0486258776301436 1.1201754823162116 0.8746791088879785 1.0310799776404336 1.2203658395250168 1.0339886863703533 0.8491624899016538 1.0947892479233794 1.0 14.535273607792451 -1.5424962577581365 23.115114334089053 1.018387720943352 0.004869074300287712 0.0 0.11172599609522481 0.0 0.0 0.02580538053334454 0.0 0.028675020842537896 1.5424962577581365 -1.0135186466430643 ATDSFS(ph)GR ddPTM_PC-9_Lapatinib_30min_R1 1 ATDSFSGR 8 0 Q9HBH9;K7EK27;Q9HBH9-2 Q9HBH9 MKNK2 MAP kinase-interacting serine/threonine-protein kinase 2 1 ATDS(0.293)FS(0.706)GR 105.2 0.003846 7040100.0 15901.0 14346.0 11422.0 10309.0 13779.0 18886.0 15951.0 17884.0 20107.0 16849.0 True False 15674.248824113727 14312.782718415614 10482.927250195033 11067.158249815868 12968.546310556301 18078.289805416287 16776.86473115759 18714.95592875184 17842.33792390332 19761.327200118714 0.7931779412072872 0.7242824620772248 0.5304768826525 0.5600412430673879 0.6562588726570143 0.914831763187833 0.8489745937234826 0.947049544761316 0.9028916804634526 1.0 14.270392223270093 -6.755072296050019 6.680663571588916 0.9155542885892997 0.6439751048792149 0.7472665592880073 0.07836246540630867 0.0794158718505119 16.291944479722787 0.029005611357186184 0.027510133256006777 1.757631000625729e-07 6.755072296050019 -0.2715791837100847 ATEDGEEDEEMIES(ph)IENLEDLKGHSVR ddPTM_PC-9_AZD4547_30min_R2 2 ATEDGEEDEEMIESIENLEDLKGHSVR 27 1 P49736;H0Y8E6 P49736 MCM2 DNA replication licensing factor MCM2 1 ATEDGEEDEEMIES(1)IENLEDLKGHSVR;ATEDGEEDEEMIES(0.987)IENLEDLKGHS(0.013)VR 88.76799999999999 2.4647e-07 5877100.0 29614.0 24031.0 37299.0 53302.0 42596.0 35097.0 30326.0 38356.0 31884.0 41759.0 True False 39030.63599053438 31798.550798182154 36804.39088926636 41014.04740769083 36682.28066048058 32902.37904176174 33024.95525075355 32428.96153319634 33569.32314752391 40297.03012045035 0.9685735120893366 0.7891040779713615 0.9133276268562653 1.0177933035039375 0.9102973730529259 0.8164963756240713 0.8195381930638532 0.8047481771302784 0.8330470768486684 1.0 15.298385896010323 -6.7077313224345 7.729191430804071 0.8404327129686485 0.9179989837286793 0.14351682697348467 0.07549591094534816 0.4068709488473942 50.31162379953879 0.025012873411064725 0.024883246950555948 1.9600568934889107e-07 6.7077313224345 0.07756627076003075 ATEDGEEDEEMIES(ph)IENLEDLKGHSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATEDGEEDEEMIESIENLEDLKGHSVR 27 1 P49736;H0Y8E6 P49736 MCM2 DNA replication licensing factor MCM2 1 ATEDGEEDEEMIES(1)IENLEDLKGHSVR;ATEDGEEDEEMIES(0.981)IENLEDLKGHS(0.019)VR 91.883 9.6503e-08 5379500.0 25090.0 21780.7 27160.6 35267.1 33757.9 34963.0 29414.6 35328.6 31439.7 24230.2 True False 29337.24144991159 23942.943952368387 27808.211711149088 33291.1987244809 27143.281828112787 33129.47873115617 26628.2361447378 34401.261683745855 31899.446134431197 28622.943453842337 1.024955434692492 0.836494820701408 0.9715357107137812 1.16309487101376 0.948305050173625 1.157444858338246 0.9303108950929094 1.201877149330281 1.114471199856597 1.0 14.80488441946547 -5.560571526701016 9.025308290450395 1.0739991637640014 0.9240480771943059 0.2805458818387747 0.09626234909928394 0.32045858012115874 71.77733023614839 0.02465180511192747 0.042936210919407865 2.7506065529187034e-06 5.560571526701016 -0.14995108656969547 ATEETGQAQSGQANCQGLS(ph)PVSVASK ddPTM_PC-9_AZD4547_30min_R2 1 ATEETGQAQSGQANCQGLSPVSVASK 26 0 Q9UHF7;Q9UHF7-3;Q9UHF7-2;H0YC29;E5RJ97;E5RFF3 Q9UHF7 TRPS1 Zinc finger transcription factor Trps1 1 ATEETGQAQS(0.009)GQANCQGLS(0.936)PVS(0.052)VAS(0.003)K 70.154 0.0030953000000000005 0.0 5541.6 4467.6 4221.1 6620.7 6351.8 6875.2 5730.9 6819.5 7303.9 7148.7 True False 7303.713527559439 5911.6643313203185 4165.1254559822555 5094.399903795329 5469.9622100488405 6445.292657147913 6240.938997775624 5765.7029715202925 7689.969242792618 6898.426188894933 1.0587506958205823 0.8569584089827472 0.603779085537983 0.7384872671387395 0.7929290044234104 0.9343134913182846 0.9046902622256464 0.8357997626765804 1.1147425560879247 1.0 12.752051546776537 -7.803721738111513 0.9611479378856638 1.036433012352435 0.8080584996551639 0.2903046217644053 0.12244067428781015 0.7491349829111928 1.2603525533372322 0.11641657988877749 0.04717578717901106 1.5713692922269413e-08 7.803721738111513 -0.22837451269727116 ATEETGQAQSGQANCQGLS(ph)PVSVASK ddPTM_PC-9_Lapatinib_30min_R1 1 ATEETGQAQSGQANCQGLSPVSVASK 26 0 Q9UHF7;Q9UHF7-3;Q9UHF7-2;H0YC29;E5RJ97;E5RFF3 Q9UHF7 TRPS1 Zinc finger transcription factor Trps1 1 ATEETGQAQS(0.017)GQANCQGLS(0.944)PVS(0.037)VAS(0.002)K 89.23899999999999 0.00012858 0.0 11885.0 14179.0 18526.0 11814.0 15604.0 17998.0 14037.0 16596.0 17962.0 12772.0 True False 11715.517720557931 14146.169396655161 17002.863792428056 12682.840970348701 14686.203398644358 17228.26749538718 14763.767176431504 17367.11074667668 15938.93041175469 14979.623182379744 0.7820969578419489 0.9443608310050843 1.1350661886093512 0.8466728979716456 0.9804120717749075 1.1501135432867546 0.98559002430701 1.1593823512934087 1.0640408118211786 1.0 13.870713712308087 -6.572671019606179 7.760051301816766 1.075716159157635 0.939482858048192 0.32150066025947766 0.09909586637783642 0.3033479819757846 40.66591338655853 0.03266284090868202 0.032720130613755394 2.675031992418738e-07 6.572671019606179 -0.13623330110944298 ATENDIANFFS(ph)PLNPIR ddPTM_PC-9_AZD4547_30min_R2 2 ATENDIANFFSPLNPIR 17 0 P31942;P31942-2;P31942-3;P31942-4;P31942-5;P31942-6 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 1 ATENDIANFFS(1)PLNPIR;ATENDIANFFS(1)PLNPIR 194.67 4.4089e-12 58626000.0 91767.0 77186.0 120099.0 174797.0 128187.0 121159.0 98300.0 138129.0 107260.0 125916.0 True False 120946.99712782358 102134.86504550323 118506.40878870733 134500.25223672905 110390.44771868283 113582.90857682464 107048.5095676673 116784.33693865048 112929.54462437019 121507.71916584752 0.9953852969846417 0.8405627703874351 0.9752994262607821 1.106927635215898 0.9085056363210096 0.9347793651018484 0.8810017199117641 0.9611268958085697 0.9294022256333454 1.0 16.890688442988385 ATENDIYNFFS(ph)PLNPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ATENDIYNFFSPLNPVR 17 0 P31943;G8JLB6;E9PCY7;H0YB39;H0YBD7;H0YBG7;P52597 P31943;P52597 HNRNPH1;HNRNPF Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;Heterogeneous nuclear ribonucleoprotein F;Heterogeneous nuclear ribonucleoprotein F, N-terminally processed 1 ATENDIYNFFS(1)PLNPVR;ATENDIYNFFS(1)PLNPVR;ATENDIYNFFS(1)PLNPVR 144.4 3.3359000000000004e-05 8242450.0 13727.4 14630.5 16953.4 17444.6 20347.5 16183.5 18936.7 16343.58 17658.9 13226.6 True False 16051.177691491303 16082.919350393955 17357.633352127537 16467.235618156275 16360.553440750906 15334.80877057648 17142.878686164564 15914.578342454413 17917.12800514341 15624.477878292017 1.0273097006199563 1.0293412346750401 1.1109256569938566 1.0539382977421057 1.0471104102289115 0.9814605575961043 1.0971808990802918 1.018567050139029 1.1467345113680059 1.0 13.931520359725162 ATENDIYNFFSPLNPVR ddPTM_PC-9_Lapatinib_30min_R1 1 ATENDIYNFFSPLNPVR 17 0 P31943;G8JLB6;E9PCY7;H0YB39;H0YBD7;H0YBG7;P52597 P31943;P52597 HNRNPH1;HNRNPF Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;Heterogeneous nuclear ribonucleoprotein F;Heterogeneous nuclear ribonucleoprotein F, N-terminally processed 0 128.73 0.00014595 44228000.0 64513.0 59051.0 57189.0 64082.0 67161.0 63218.0 45683.0 52732.0 74204.0 61419.0 False True 63593.032789764744 58914.27103758261 52487.14117592397 68794.80405128526 63210.722023606366 60514.313508355735 48048.24221136431 55182.12122763042 65846.36411723895 72035.19231432691 0.8828050671715479 0.8178540119738847 0.7286319296115064 0.9550165945430928 0.8774977895218936 0.840065967260841 0.6670106744729009 0.7660439217937005 0.9140860460247973 1.0 16.136414277399254 -7.020011867567563 24.81829692433743 0.8081816226520647 0.8502241442774048 0.0 0.09916359072357064 2973.459449065703 3687614.60530336 0.03767713573250869 0.029600166238638446 9.54966490170208e-08 7.020011867567563 0.04204252162534006 ATEPPS(ph)PDAGELSLASR ddPTM_PC-9_AZD4547_30min_R2 3 ATEPPSPDAGELSLASR 17 0 Q8IYB8 Q8IYB8 SUPV3L1 ATP-dependent RNA helicase SUPV3L1, mitochondrial 1 ATEPPS(0.998)PDAGELS(0.001)LAS(0.002)R;AT(0.001)EPPS(0.999)PDAGELSLASR;ATEPPS(1)PDAGELSLASR 239.7 1.0855999999999998e-37 25710800.0 34807.1 36534.0 43476.0 62449.0 56192.0 47891.0 36656.0 58360.0 47957.0 41878.0 True False 45875.03376734414 48342.90103869113 42899.479833286256 48052.347877432076 48390.71074452352 44896.368199248136 39918.312987918674 49341.80297938622 50491.90911384405 40411.863966671175 1.135187275825203 1.1962551660215652 1.0615565733039853 1.1890653674639267 1.197438227161032 1.1109699922843317 0.9877869781220795 1.2209732028218205 1.2494328189238233 1.0 15.302491275823476 -6.832420457498423 24.999546534551545 1.1197654339619387 1.1547473660852416 0.0551372215740048 0.0852563007047108 200.5926276732535 70644.28852899207 0.03102673863435608 0.02736302006155725 1.470887788803236e-07 6.832420457498423 0.03498193212330292 ATEPPS(ph)PDAGELSLASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ATEPPSPDAGELSLASR 17 0 Q8IYB8 Q8IYB8 SUPV3L1 ATP-dependent RNA helicase SUPV3L1, mitochondrial 1 ATEPPS(1)PDAGELSLASR;ATEPPS(0.877)PDAGELS(0.062)LAS(0.062)R;ATEPPS(1)PDAGELSLASR;ATEPPS(0.999)PDAGELS(0.001)LASR 196.45 3.4667e-12 24472800.0 59464.4 60121.9 66824.5 68146.7 93496.0 64452.7 70418.0 69589.1 63786.4 53538.3 True False 69530.54844456459 66090.40490020507 68417.84951332753 64328.661333582306 75176.12996665193 61072.686949506286 63747.497257829265 67762.45986074606 64719.155427986974 63244.36998105037 1.0993950681364637 1.0450006051132685 1.081801424124033 1.01714447235156 1.1886612197920008 0.9656620339139315 1.0079552895685362 1.0714386099671707 1.0233188416198704 1.0 15.948649436242778 -6.814091125031668 24.999997854763215 1.0177825145690984 1.080000179903585 0.35594580418181077 0.048375147342332774 129.72383158301284 61594.178923104046 0.0167545110502477 0.014776106328431456 1.5342950184249757e-07 6.814091125031668 0.06221766533448658 ATEPPS(ph)PDAGELSLASR ddPTM_PC-9_Lapatinib_30min_R1 3 ATEPPSPDAGELSLASR 17 0 Q8IYB8 Q8IYB8 SUPV3L1 ATP-dependent RNA helicase SUPV3L1, mitochondrial 1 ATEPPS(1)PDAGELSLASR;ATEPPS(1)PDAGELSLASR;ATEPPS(1)PDAGELSLASR 216.77 2.1187e-22 13811800.0 55478.4 42362.9 40532.0 33726.3 39270.6 34189.4 31812.8 27341.6 44080.7 25955.9 True False 54687.26784250745 42264.811307818825 37199.61541804455 36206.64460963868 36960.78051697017 32727.199061384053 33459.91112277412 28611.9905514181 39115.86737565051 30442.342730937227 1.7964211337431386 1.3883560697471202 1.2219695358806997 1.1893514546383266 1.2141240522664682 1.0750552068426988 1.0991240529189061 0.939874792301743 1.2849164639322832 1.0 14.893791767177099 -1.5228787831097756 0.6421654838156066 1.0884658006551005 60.44453116778736 0.8460363767823291 0.09018630393555634 73.01831460745409 0.4853830569890528 0.03665635924624263 6150.189711001483 0.029999997386835106 1.5228787831097756 59.35606536713226 ATFDAISK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATFDAISK 8 0 H0YEN5;P15880;E9PQD7 H0YEN5 RPS2 40S ribosomal protein S2 0 92.06200000000001 0.038041000000000005 2998200.0 25732.0 22915.0 22180.0 29307.0 33322.0 27908.0 27638.0 27583.0 23866.0 20613.0 False True 30087.919369833624 25189.84976004086 22708.855318118425 27665.023804575976 26792.79330397848 26444.45535077383 25019.928558207917 26858.975476604268 24214.99509996391 24349.97372758177 1.2356448391462678 1.0344918660634013 0.9326028673450102 1.1361418338303655 1.1003212407424354 1.086015765217011 1.0275135750913469 1.1030391973762375 0.994456723891042 1.0 14.571632595261258 -7.174724639043709 0.011313362052018838 2.709845996591786e-07 2.121094324347299 0.15628733250902438 0.07483882715752734 3313.4728367563116 20.641000094527616 1894.7273586732651 1971.9321846947046 6.687678100735842e-08 7.174724639043709 2.1210940533626994 ATFDAISK ddPTM_PC-9_Lapatinib_30min_R1 2 ATFDAISK 8 0 H0YEN5;P15880;E9PQD7 H0YEN5 RPS2 40S ribosomal protein S2 0 ; 112.41 0.007659399999999999 0.0 131356.0 127436.0 135435.0 132836.0 139140.0 132803.0 151334.0 116291.0 117315.0 126830.0 False True 129482.83935225997 127140.9297716448 124300.0570942183 142605.20256790557 130956.05875976528 127123.32526891334 159169.33403705098 121694.30440116729 104101.74931828317 148752.3965096479 0.8704588456419381 0.8547151693344222 0.8356171733082388 0.9586749922288235 0.880362682098178 0.8545968216429258 1.0700287038853016 0.8180997903672386 0.699832417903474 1.0 17.182553385914424 -4.5228280086688555 21.575682225250837 0.8840687842797534 0.8568248164955732 0.0019232991418953738 0.09796616595196486 20282.469486713453 657.923888030995 0.023625022931788517 13743.212717901783 3.0003504965688493e-05 4.5228280086688555 -0.027243967784180256 ATFSGS(ph)AGR ddPTM_PC-9_AZD4547_30min_R2 2 ATFSGSAGR 9 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 AT(0.002)FS(0.007)GS(0.991)AGR;AT(0.052)FS(0.023)GS(0.925)AGR 93.667 0.0060795 83006000.0 88488.0 67171.0 122927.0 163191.0 127684.0 99082.0 97723.0 140329.0 98667.0 99488.0 True False 116625.34333526071 88882.71214950249 121296.90766092502 125569.83622581656 109957.28058627104 92886.38687682246 106420.15768546423 118644.3774896212 103882.33618732731 96004.95540179026 1.214784620722671 0.9258137955225283 1.2634442373655135 1.3079516125005668 1.1453292189563435 0.9675165879519836 1.1084860905365284 1.2358151409277023 1.0820518144357179 1.0 16.550821253602827 -6.534215034996874 24.91538653356259 1.0910419999293464 1.17365762113626 0.13819641411943273 0.11580417082466778 555.6201121956043 1221156.66124735 0.04025183972317702 0.04028499684890221 2.9227048820089407e-07 6.534215034996874 0.08261562120691357 ATFSGS(ph)AGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATFSGSAGR 9 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 AT(0.003)FS(0.009)GS(0.988)AGR 73.84100000000001 0.028506999999999998 27028000.0 47335.0 45109.0 56707.0 60862.0 69450.0 78151.0 75281.0 60510.0 52964.0 45347.0 True False 55347.88059113453 49587.1234050047 58059.1099424951 57452.099457266304 55841.771050996475 74052.62398302728 68149.83869275807 58921.67661564458 53738.498301956264 53568.052133345525 1.0332255586475037 0.9256846465420993 1.0838383631715804 1.0725067865871307 1.0424454283308835 1.3824027761675943 1.2722105056781698 1.0999406226116346 1.0031818623568103 1.0 15.709085216606542 -5.91902290119951 1.4631156274445072 1.157854826024017 0.9902570777208821 0.1779015385424615 0.11725542015955599 0.6416453081185763 2.7904285304629814 0.04295700876690459 0.08264059656314761 1.204972398139433e-06 5.91902290119951 -0.16759774830313479 ATFSGS(ph)AGR ddPTM_PC-9_Lapatinib_30min_R1 1 ATFSGSAGR 9 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 ATFS(0.002)GS(0.998)AGR 79.07 0.020681 35673000.0 44237.0 35011.0 39608.0 41152.0 42128.0 44711.0 30106.0 37549.0 50290.0 30865.0 True False 43606.17226792772 34929.934180569406 36351.58313130143 44178.45535904769 39650.11386683471 42798.81475643163 31664.741370210675 39293.66361936383 44625.81062282277 36199.974124972665 1.204591255159099 0.964915998557935 1.0041880970910466 1.2204001916280667 1.0953077957998307 1.182288545529836 0.8747172376669368 1.0854610968425245 1.2327580806760168 1.0 15.143701045648346 -12.05373371095065 1.9803834660308226 6.0252090469009026e-05 1.0888577540087714 0.05746039875101139 0.11339052648208249 3127744.4919199063 391444.61602659104 13816002.81149989 0.02851184078383956 8.836215297152484e-13 12.05373371095065 1.0887975019183023 ATFYGEQVDYYK ddPTM_PC-9_Lapatinib_30min_R1 1 ATFYGEQVDYYK 12 0 P46940;H0YLE8 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 0 103.21 0.009977600000000001 4217400.0 15492.0 8894.3 11001.0 12779.0 10458.0 9487.3 11257.0 10419.0 12005.0 10692.0 False True 15271.081239115145 8873.70579481416 10096.540245088043 13718.81028949433 9842.881001219086 9081.55029497648 11839.832379075975 10903.104776429522 10652.870481745626 12540.097953805534 1.2177800600417832 0.7076265135649329 0.805140460806692 1.093995464790695 0.7849126089347711 0.7242009056412919 0.944157886381019 0.8694592990097628 0.8495045669490011 1.0 13.614260996981072 -4.745420598662397 24.986662310238277 0.8612143764585235 1.217781067777574 0.4600404882979733 0.11483092913512821 855.6419203560376 1334587.7472673315 0.028532964313192112 0.7276687174939603 1.7971296163576415e-05 4.745420598662397 0.3565666913190505 ATGAALT(ph)PTEER ddPTM_PC-9_AZD4547_30min_R2 1 ATGAALTPTEER 12 0 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 AT(0.001)GAALT(0.575)PT(0.424)EER 98.59200000000001 0.008826899999999999 22722000.0 61150.0 50314.0 68515.0 120890.0 117390.0 94734.0 79344.0 128800.0 91944.0 101040.0 True False 80594.42800098512 66577.01655610412 67606.44633309435 93020.67823188151 101092.42479889677 88810.26800416732 86405.4622903051 108896.91952955684 96803.97213260373 97502.62035418247 0.8265873030716753 0.6828228442913662 0.6933808146643755 0.9540325982417692 1.0368175176387484 0.9108500641476116 0.8861860530151245 1.116861466225052 0.9928345697885773 1.0 16.57315337093668 -5.812487045622511 5.793281869436887 0.98706172953126 0.7290546332843882 0.7304016993376512 0.07001573491794266 0.09716457828869003 7.129982203163082 0.020529242284346997 0.03136892915892162 1.5399724605299488e-06 5.812487045622511 -0.2580070962468718 ATGAALT(ph)PTEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ATGAALTPTEER 12 0 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 ATGAALT(0.987)PT(0.012)EER;ATGAALT(0.647)PT(0.353)EER;AT(0.003)GAALT(0.815)PT(0.181)EER 151.3 0.00045442 81702000.0 237458.0 238901.0 211871.0 256143.0 340959.0 344730.0 322284.0 352180.0 281701.0 268851.0 True False 277654.9493907177 262617.51243829477 216922.80816524226 241792.13813681074 274150.53154466144 326651.75193751836 291754.9263858988 342935.64816555404 285820.34419906716 317591.5580766553 0.874251667998372 0.8269033157830606 0.6830244779771029 0.7613304950582178 0.8632173134730843 1.0285278170356034 0.9186482416370763 1.0798008934569399 0.8999620327756958 1.0 18.27681303904989 -6.567123642293454 3.8915626553110187 0.9856443329280085 0.7836881787081573 0.6687842822407266 0.06623364928403626 0.13309812068884144 4.284738757061363 0.0225745731672265 0.023161363295492073 2.7094201585532865e-07 6.567123642293454 -0.20195615421985114 ATGAALT(ph)PTEER ddPTM_PC-9_Lapatinib_30min_R1 3 ATGAALTPTEER 12 0 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 ATGAALT(0.934)PT(0.066)EER;ATGAALT(0.648)PT(0.352)EER;AT(0.002)GAALT(0.706)PT(0.292)EER 132.97 0.00017508 91194000.0 345090.0 325353.0 322122.0 243195.0 388100.0 382900.0 408490.0 374350.0 460920.0 339350.0 True False 340168.95331824437 324599.66511812934 295638.37258687895 261080.3715747376 365272.7210339573 366524.2595834956 429639.61344307975 391743.66763186327 409006.33589722525 398006.1953445483 0.8546825584555661 0.8155643528039256 0.7427984188310159 0.6559706221374871 0.9177563698920462 0.9209008901637844 1.0794797127998141 0.9842652506771568 1.027638113882007 1.0 18.602431362299434 -6.654292126889606 2.2144242596389936 1.0149724435438219 0.7709438756600273 0.7595228717760557 0.06199107381520766 0.15076654320460364 1.511492489147975 0.024037303364416188 0.023750785999211658 2.2167048582892906e-07 6.654292126889606 -0.24402856788379457 ATGAALT(ph)PTEERR ddPTM_PC-9_AZD4547_30min_R2 2 ATGAALTPTEERR 13 1 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 ATGAALT(0.842)PT(0.158)EERR;ATGAALT(0.832)PT(0.168)EERR 116.9 0.00091002 12097700.0 34904.0 41275.0 56301.0 79802.0 73624.0 68884.0 58495.0 73526.0 52541.0 55216.0 True False 46002.745951698904 54616.336573383065 55554.41195358007 61404.881828609534 63402.578442746344 64576.67259061213 63700.94168016976 62164.246159396025 55318.20999542258 53282.90464644238 0.8633678335846963 1.0250255111989228 1.0426310713015785 1.1524312016407583 1.1899234635095974 1.2119585638040815 1.1955230688502447 1.1666827582295973 1.0381980930372587 1.0 15.70138511069728 -4.822550456162897 1.1017738135938755 1.1500488419059125 0.7477614235948867 0.5844069024986269 0.06894070268575128 1.0675536921816524 1.119849555341476 0.021907691135025883 0.49510361137472636 1.5046986933419749e-05 4.822550456162897 -0.40228741831102577 ATGAALT(ph)PTEERR ddPTM_PC-9_Lapatinib_30min_R1 3 ATGAALTPTEERR 13 1 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 ATGAALT(0.988)PT(0.012)EERR;ATGAALT(0.928)PT(0.072)EERR;ATGAALT(0.553)PT(0.447)EERR 132.31 0.00019668 32600600.0 138036.0 99816.0 98498.0 79164.0 135097.0 123358.0 117710.0 128011.0 133176.0 69752.0 True False 136067.5813272978 99584.88218467696 90399.87465327518 84985.9846433626 127150.86007092119 118082.26590154304 123804.4478405467 133958.85838713113 118176.3164745487 81808.5402613023 1.6632442150011266 1.2172920072476021 1.105017573526328 1.0388400082914486 1.5542492222058026 1.4433977861526421 1.5133438079338228 1.6374678971077714 1.4445474286313522 1.0 16.319963838235935 -6.281648821810134 24.90608895512227 1.4686613978688765 1.24253504254611 0.11677682885412499 0.22287145484610846 1307.3982346520845 1611231.8426820117 0.06834915021806214 0.07759793430759875 5.228187786193468e-07 6.281648821810134 -0.2261263553227666 ATGAALTPT(ph)EER ddPTM_PC-9_AZD4547_30min_R2 1 ATGAALTPTEER 12 0 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 ATGAALT(0.23)PT(0.77)EER 131.35 0.00029112 53770000.0 146190.0 112720.0 140920.0 314740.0 245610.0 244860.0 215720.0 298630.0 220180.0 213840.0 True False 192675.3790591009 149154.53564025997 139051.3087245076 242181.5556845263 211511.29103720142 229548.86549180176 234918.6620949865 252483.5953347174 231818.2652936209 206353.52668783057 0.9337149800719334 0.722810693058323 0.6738499261748162 1.1736245053417285 1.0249947962225694 1.1124058269140262 1.1384281425457243 1.2235487291509775 1.123403457234405 1.0 17.654758569392207 -5.7658716563211 24.999726288087174 1.120358106501365 0.7713937252582572 0.7587733526413107 0.08699901762631085 49.183971470099344 277418.45673908695 0.024445606777857735 0.03770109970784329 1.7144638948645432e-06 5.7658716563211 -0.3489643812431078 ATGDGS(ph)SPELPSLER ddPTM_PC-9_AZD4547_30min_R2 1 ATGDGSSPELPSLER 15 0 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2;H3BS99 H3BSS6 ZNF106 Zinc finger protein 106 1 ATGDGS(0.603)S(0.397)PELPSLER 122.1 5.5462e-05 9092400.0 52626.0 45192.0 74533.0 87243.0 81984.0 72348.0 75334.0 92155.0 70649.0 70108.0 True False 69359.97331119938 59799.430222273215 73544.64372100295 67130.47424091349 70601.93674685055 67824.06812301288 82038.58005870448 77914.56226122915 74383.36190720796 67653.54025921444 1.0252231153823843 0.8839068878458065 1.0870775341425853 0.9922684605078046 1.0435808159682307 1.002520605176685 1.2126280419971192 1.151670141173686 1.099474789082851 1.0 16.045877810880214 -7.233015446385786 24.223961303829913 1.1285824185964164 1.005025700748188 0.370346464383735 0.06960109980894934 461.49071269070134 393300.37702402455 0.025810669504040297 0.019987954598535057 5.847692855090222e-08 7.233015446385786 -0.12355671784822841 ATGDGS(ph)SPELPSLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATGDGSSPELPSLER 15 0 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2;H3BS99 H3BSS6 ZNF106 Zinc finger protein 106 1 AT(0.001)GDGS(0.812)S(0.187)PELPSLER 86.738 0.0053827 7080300.0 24515.0 24729.0 23876.0 27096.0 33150.0 22898.0 23449.0 24843.0 21694.0 17473.0 True False 28664.905306679288 27183.93169173249 24445.294390234234 25577.89896641726 26654.495469266152 21697.188570374794 21227.74096394159 24190.897573334296 22011.2337089842 20640.716583808102 1.3887553365838992 1.3170052299956148 1.1843239206826126 1.2391962683350926 1.2913551407500863 1.051183881251267 1.0284401162987717 1.1719989214091133 1.0663987182620984 1.0 14.333205437227317 -1.5228787452803376 0.1903461934092174 0.9887369775864373 2.801128704756667 0.7403085320736065 0.06502716064267498 29.841056736862893 0.34920153623198635 0.14104669945505696 15.893339815130686 0.029999999999999995 1.5228787452803376 1.8123917271702297 ATGDGS(ph)SPELPSLER ddPTM_PC-9_Lapatinib_30min_R1 1 ATGDGSSPELPSLER 15 0 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2;H3BS99 H3BSS6 ZNF106 Zinc finger protein 106 1 AT(0.003)GDGS(0.499)S(0.499)PELPSLER 73.415 0.017649 1882500.0 8529.9 9704.5 12701.0 12933.0 12832.0 12349.0 10234.0 11078.0 13513.0 10939.0 True False 8408.262061807922 9682.029826492706 11656.772807277806 13884.13596322326 12077.246988682658 11820.862056924998 10763.866444653415 11592.724322227294 11991.02364180164 12829.791574698715 0.6553701213969546 0.7546521523846401 0.9085707074357945 1.0821793855641264 0.941343974168674 0.9213604124510175 0.8389743809931055 0.9035785386482031 0.934623417066947 1.0 13.64721011298632 -5.150185092221725 2.785384270339206 0.93994352256768 0.6684760018979005 0.7207177738417505 0.060482104124368836 0.16297061052817036 2.343849991863926 0.017681967565788465 0.06694510326712297 7.0764412883814126e-06 5.150185092221725 -0.2714675206697795 ATGDGSS(ph)PELPSLER ddPTM_PC-9_AZD4547_30min_R2 2 ATGDGSSPELPSLER 15 0 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2;H3BS99 H3BSS6 ZNF106 Zinc finger protein 106 1 ATGDGS(0.085)S(0.915)PELPSLER;ATGDGS(0.073)S(0.927)PELPSLER 247.17 2.9474e-40 11419800.0 37047.3 39590.8 56550.0 65515.0 57590.0 55559.0 39788.3 56053.0 53523.0 53319.0 True False 48827.57076828951 52387.75185970911 55800.11005088638 50411.52894665991 49594.622575760055 52084.886947067826 43329.381619849526 47391.296819800176 56352.11651062983 51452.31803904051 0.9489868023291114 1.0181805962553294 1.084501382591682 0.9797717744885492 0.9638948149649761 1.0122942742355618 0.8421269103361381 0.9210721426358488 1.0952298877549402 1.0 15.65094845468803 -5.982812764556164 24.643730734489218 0.9646824428469674 1.0197883555622045 0.07312723181619818 0.06832452677647095 470.233768047008 674233.2530776729 0.019730138743862292 0.02925675557411909 1.0403685986325117e-06 5.982812764556164 0.055105912715237126 ATGDGSS(ph)PELPSLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATGDGSSPELPSLER 15 0 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2;H3BS99 H3BSS6 ZNF106 Zinc finger protein 106 1 ATGDGS(0.13)S(0.869)PELPS(0.001)LER;ATGDGS(0.183)S(0.817)PELPSLER 169.3 0.00018066 11644400.0 29621.0 36259.0 41386.0 41575.0 45429.0 32825.0 40084.0 40362.0 36504.0 30614.0 True False 34635.250258582375 39858.55389261713 42372.799197279004 39245.687537968624 36527.51356480517 31103.59921489004 36286.95333697107 39302.540267074 37037.801941216894 36164.07585970933 0.9577252960352781 1.1021587845142158 1.1716820681843239 1.0852119570319931 1.0100496887161092 0.860068962789197 1.0033977773340155 1.0867840345081583 1.0241600555450938 1.0 15.142269664913538 -6.290048456903044 5.361163816471223 0.9945567189316827 1.0877261627726378 0.2340490661084078 0.07200677878763335 0.2814326661440021 24.1055739992295 0.02416578889958879 0.02834165831429062 5.128041640886971e-07 6.290048456903044 0.09316944384095505 ATGDGSS(ph)PELPSLER ddPTM_PC-9_Lapatinib_30min_R1 3 ATGDGSSPELPSLER 15 0 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2;H3BS99 H3BSS6 ZNF106 Zinc finger protein 106 1 ATGDGS(0.176)S(0.824)PELPSLER;ATGDGS(0.025)S(0.975)PELPSLER;ATGDGS(0.003)S(0.997)PELPSLER 241.3 1.2926999999999999e-32 19444400.0 66307.9 72401.0 78071.2 81342.7 84657.0 73199.9 66581.2 72358.5 79519.0 60471.8 True False 65362.33718662036 72233.35993280415 71652.48729954711 87324.9135092924 79677.64170206577 70069.3109143011 70028.44875168632 75720.54006769137 70562.73284780768 70924.27005639141 0.9215792722949592 1.0184575727796972 1.0102675324339143 1.231241624903026 1.1234185651641477 0.9879454643465411 0.9873693264098053 1.0676252290998056 0.994902489538542 1.0 16.11399177709077 -10.312488939128809 15.014720908137162 0.9999938324493101 1.0427866631190663 0.01617437438470737 0.08206454356438692 0.0 0.0 0.08502186168200704 0.020620830364798233 4.869799277035095e-11 10.312488939128809 0.042792830669756254 ATGEPGTFVCTSHLPAAAS(ph)ASPK ddPTM_PC-9_AZD4547_30min_R2 3 ATGEPGTFVCTSHLPAAASASPK 23 0 Q8IY33-4;Q8IY33-2;Q8IY33 Q8IY33-4 MICALL2 MICAL-like protein 2 1 ATGEPGTFVCTSHLPAAAS(0.96)AS(0.04)PK;ATGEPGTFVCT(0.023)S(0.084)HLPAAAS(0.84)AS(0.053)PK;ATGEPGTFVCTSHLPAAAS(0.826)AS(0.173)PK 134.06 8.431999999999999e-07 42854000.0 102537.0 118254.0 132771.0 179925.0 191100.0 168298.0 175878.0 166924.0 149982.0 183268.0 True False 135141.63309790718 156477.29291699186 131010.36978896968 138446.0710635394 164569.0636261113 157774.29945495084 191530.8012791675 141129.73133192345 157909.74232567847 176851.8431024374 0.7641516804528267 0.8847931136706105 0.740791656398429 0.7828364614970265 0.9305476309386748 0.8921269729915322 1.0830014430114119 0.7980110857548557 0.8928928280052635 1.0 17.432181728934452 -6.264334373647251 24.361378993197274 0.9281439759025566 0.7959502456687481 0.43425686765373295 0.0779377859134409 185.5597423395989 1561484.883127089 0.02380371338263914 0.028182303516742148 5.440835886485378e-07 6.264334373647251 -0.13219373023380854 ATGEPGTFVCTSHLPAAAS(ph)ASPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ATGEPGTFVCTSHLPAAASASPK 23 0 Q8IY33-4;Q8IY33-2;Q8IY33 Q8IY33-4 MICALL2 MICAL-like protein 2 1 ATGEPGTFVCTSHLPAAAS(0.914)AS(0.086)PK;ATGEPGTFVCTSHLPAAAS(0.541)AS(0.459)PK;ATGEPGTFVCTSHLPAAAS(0.93)AS(0.07)PK;ATGEPGTFVCTS(0.001)HLPAAAS(0.961)AS(0.038)PK 116.05 1.7003e-08 82225500.0 206966.0 257828.0 263463.0 388268.0 408086.0 365989.0 417369.0 364124.0 319001.0 297883.0 True False 242001.25603516976 283423.4599141088 269744.95710899145 366514.60274184024 328124.47776986245 346795.892553188 377832.7868301144 354566.13082126935 323665.7861344001 351886.82985946944 0.6877246759471393 0.8054392374596617 0.7665673569446109 1.0415695378204766 0.9324716071383041 0.985532458522774 1.0737338108988246 1.0076140984386086 0.91980079579466 1.0 18.424751993491725 -5.753255285134145 24.94616395923339 0.995063289433465 0.7584632082526215 0.8272508018948606 0.05048083537891376 69.55698426255884 212016.1414860357 0.013895955598547522 0.02354777126811027 1.765000020897466e-06 5.753255285134145 -0.23660008118084352 ATGEPGTFVCTSHLPAAAS(ph)ASPK ddPTM_PC-9_Lapatinib_30min_R1 1 ATGEPGTFVCTSHLPAAASASPK 23 0 Q8IY33-4;Q8IY33-2;Q8IY33 Q8IY33-4 MICALL2 MICAL-like protein 2 1 ATGEPGTFVCTS(0.001)HLPAAAS(0.774)AS(0.224)PK 115.12 1.8757999999999998e-08 10274000.0 55161.0 51682.0 44896.0 55953.0 46975.0 49997.0 43355.0 43927.0 41407.0 29754.0 True False 54374.39402471151 51562.33350433262 41204.82418357172 60067.97027373625 44212.02285640337 47858.74485869946 45599.70976235577 45968.00878339761 36743.307624959685 34896.939255287114 1.558142209175936 1.477560342101366 1.1807575410020785 1.7212962384555133 1.2669312495566487 1.3714310160152097 1.3066965394521561 1.317250445579784 1.0529091779701807 1.0 15.09081288547262 -8.059422881523885 0.6307647412780034 0.9816527388406994 1.4575411517507881 0.5454638894365558 0.14159126482541023 0.5589024577647751 0.49269957640961615 0.13423065466060063 0.06485711543705877 8.721217518140647e-09 8.059422881523885 0.47588841291008876 ATGEPGTFVCTSHLPAAASAS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 ATGEPGTFVCTSHLPAAASASPK 23 0 Q8IY33-4;Q8IY33-2;Q8IY33 Q8IY33-4 MICALL2 MICAL-like protein 2 1 ATGEPGTFVCTSHLPAAAS(0.142)AS(0.858)PK 75.718 0.00021348 29593000.0 18459.0 21962.0 34051.0 39691.0 39189.0 33553.0 40149.0 32694.0 27524.0 40665.0 True False 24328.578028948275 29060.78700968234 33599.461491471826 30540.853169837086 33748.28380137977 31454.925605841858 43722.18322108105 27641.893533379956 28978.862448640317 39241.33072746267 0.6199733183849994 0.7405657879319679 0.856226352893725 0.778282810589381 0.8600188417606682 0.8015764252313805 1.114187067832603 0.7044076493062209 0.7384780768497164 1.0 15.260086345707995 -4.017239505984614 0.8102587758142615 0.8607188359132611 4.1896314935002064e-12 0.304087761975542 0.11506363646897551 9.90944509232803 2.0409333903809412 0.041864555518550374 10.268939754928038 9.610821118485573e-05 4.017239505984614 -0.8607188359090715 ATGEPGTFVCTSHLPAAASAS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 ATGEPGTFVCTSHLPAAASASPK 23 0 Q8IY33-4;Q8IY33-2;Q8IY33 Q8IY33-4 MICALL2 MICAL-like protein 2 1 ATGEPGTFVCTSHLPAAAS(0.168)AS(0.832)PK;ATGEPGTFVCTSHLPAAAS(0.079)AS(0.921)PK 138.12 1.0720999999999999e-06 49869900.0 118635.0 105880.0 85777.0 106341.0 98823.0 92350.0 84846.0 85939.0 91728.0 68836.0 True False 116943.24314500575 105634.84136524769 78724.74616879517 114161.67188317659 93010.42543349332 88400.40577836455 89238.91072533366 89932.03967574376 81396.6267013381 80734.21088179547 1.4484967632398689 1.3084272480214083 0.9751101213345307 1.4140433235957792 1.1520571566578102 1.0949559649228913 1.1053419578967594 1.113927276844447 1.0082048961934178 1.0 16.30089252034906 -1.5228787452803376 0.238909062217 1.0136043473780314 3.2698991607087353 0.504292283167868 0.11396002375626198 45.74561626067163 0.6098966926580108 0.15916071912011548 40.86204609404088 0.029999999999999995 1.5228787452803376 2.2562948133307037 ATGPEAAGGGGAGGGGGGYRPIIQS(ph)PGYK ddPTM_PC-9_AZD4547_30min_R2 1 ATGPEAAGGGGAGGGGGGYRPIIQSPGYK 29 1 Q9ULL5;Q9ULL5-2 Q9ULL5 PRR12 Proline-rich protein 12 1 ATGPEAAGGGGAGGGGGGY(0.034)RPIIQS(0.953)PGY(0.012)K 55.063 0.0011805 30356000.0 26439.0 21770.0 30075.0 41710.0 35089.0 29170.0 25080.0 32296.0 35235.0 26679.0 True False 34846.05203463694 28806.726764446965 29676.185849344085 32094.40391307616 30217.498030228253 27345.995288719558 27312.07141360215 27305.395288249783 37097.45016632181 25744.976330455596 1.3535088006049172 1.1189261312456287 1.1526981213122336 1.2466278275466645 1.173724055612426 1.0621876259552043 1.0608699368386183 1.0606106192433455 1.4409587987244157 1.0 14.652003323293286 -6.530376799302402 23.818199278441643 1.1239596008703168 1.2067036813185883 0.1041441338296446 0.12705543257865312 271.0456289526031 860985.6377487893 0.04129835234957184 0.04139265182844301 2.948649831221058e-07 6.530376799302402 0.08274408044827153 ATGPEAAGGGGAGGGGGGYRPIIQS(ph)PGYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATGPEAAGGGGAGGGGGGYRPIIQSPGYK 29 1 Q9ULL5;Q9ULL5-2 Q9ULL5 PRR12 Proline-rich protein 12 1 ATGPEAAGGGGAGGGGGGY(0.122)RPIIQS(0.825)PGY(0.053)K 44.11 0.014936000000000001 20074000.0 9952.2 10992.0 9932.8 10284.0 15679.0 10523.0 12135.0 10177.0 11223.0 11381.0 True False 11636.910895090095 12083.213116402745 10169.63562235377 9707.820821177853 12606.812502643252 9971.155355317229 10985.484950208169 9909.864533422819 11387.115143169985 13444.285208053569 0.8655656076173691 0.8987620337870029 0.7564281376790358 0.7220778695889722 0.9377079039569435 0.7416649677547884 0.8171118642757967 0.7371060922961143 0.8469855382381154 1.0 13.714705433071169 -8.55049307023982 21.90132029416203 1.0000000021703208 0.8089724300515783 0.40399458958575807 0.06921753072715027 1609.4015371380237 1276439.0286502608 0.0665653649778166 0.0171871033008683 2.815184934886211e-09 8.55049307023982 -0.19102757211874255 ATGPEAAGGGGAGGGGGGYRPIIQS(ph)PGYK ddPTM_PC-9_Lapatinib_30min_R1 1 ATGPEAAGGGGAGGGGGGYRPIIQSPGYK 29 1 Q9ULL5;Q9ULL5-2 Q9ULL5 PRR12 Proline-rich protein 12 1 ATGPEAAGGGGAGGGGGGY(0.052)RPIIQS(0.936)PGY(0.012)K 50.478 0.0060838 27016000.0 32426.0 22940.0 30734.0 22308.0 22978.0 30419.0 24358.0 30501.0 26779.0 25103.0 True False 31963.59929379988 22886.883839429403 28207.16915667082 23948.604737306472 21626.479216486154 29118.05028015237 25619.13805539066 31918.187809374856 23762.867024628595 29442.020102355036 1.0856455903052369 0.777354398912278 0.9580582126704872 0.8134158136584809 0.7345446793834732 0.988996345322896 0.8701555792138533 1.0841031864801205 0.8071072209725116 1.0 14.845589041829735 ATGSAGLLGDPECEGS(ph)PPEHSPEQGR ddPTM_PC-9_AZD4547_30min_R2 2 ATGSAGLLGDPECEGSPPEHSPEQGR 26 0 Q5TH69 Q5TH69 ARFGEF3 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 1 ATGSAGLLGDPECEGS(0.756)PPEHS(0.244)PEQGR;ATGSAGLLGDPECEGS(0.997)PPEHS(0.003)PEQGR 154.32 1.5703999999999998e-10 13384600.0 45293.0 50445.0 61962.0 87015.0 68159.0 55949.0 47840.0 65362.0 55308.0 63843.0 True False 59695.23184707479 66750.35974425942 61140.34339474842 66955.03611834868 58696.29935997974 52450.500185415505 52097.6673216398 55261.80476933931 58231.4679664801 61607.876002296805 0.9689545512792762 1.0834712065348737 0.9924111552306891 1.0867934501727106 0.952740187923237 0.8513603063260953 0.8456332323435001 0.8969925333455595 0.945195188425408 1.0 15.910827177598167 -6.491479144474493 5.621104813580605 0.8976039947161899 1.0328187503699497 0.5433580653938019 0.05368773996119125 0.13044948146809363 11.979140986615906 0.01660311349803621 0.018206192574198435 3.224934182168685e-07 6.491479144474493 0.13521475565375984 ATGSAGLLGDPECEGS(ph)PPEHSPEQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATGSAGLLGDPECEGSPPEHSPEQGR 26 0 Q5TH69 Q5TH69 ARFGEF3 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 1 AT(0.001)GS(0.001)AGLLGDPECEGS(0.986)PPEHS(0.012)PEQGR;ATGSAGLLGDPECEGS(0.997)PPEHS(0.003)PEQGR 100.14 1.4807999999999999e-09 8776800.0 22387.5 21167.0 23499.2 25642.0 28452.0 20601.2 21508.0 21929.0 24380.6 20401.7 True False 26177.261576719644 23268.319872170396 24059.510049212266 24205.361872485668 22877.034844390968 19520.8368056601 19470.606535564657 21353.386985696074 24737.120151436327 24100.366710231672 1.0861768989434604 0.9654757602626837 0.9983047286578398 1.0043565794461302 0.9492401140385409 0.8099809036255303 0.8078966917668735 0.8860191731701168 1.0264209025887696 1.0 14.55676747816268 -6.473055984584188 4.271582178864609 0.8914361483652895 1.0074938599818284 0.3176288307478162 0.0721039359189768 0.254618151791903 9.796734417622428 0.024097760269588212 0.02657964380270266 3.364681927109634e-07 6.473055984584188 0.11605771161653888 ATGSAGLLGDPECEGS(ph)PPEHSPEQGR ddPTM_PC-9_Lapatinib_30min_R1 1 ATGSAGLLGDPECEGSPPEHSPEQGR 26 0 Q5TH69 Q5TH69 ARFGEF3 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 1 ATGSAGLLGDPECEGS(0.936)PPEHS(0.064)PEQGR 110.03 2.4139e-10 2926000.0 17963.0 21965.0 23307.0 21748.0 22708.0 20238.0 18123.0 18129.0 21871.0 17220.0 True False 17706.844325989237 21914.141392025573 21390.788427621756 23347.420469201235 21372.36008564572 19372.467917082202 19061.32026347996 18971.339523168317 19407.657668159827 20196.45405579231 0.8767303545995958 1.085048956192418 1.0591358447641412 1.1560158236047002 1.058223390433043 0.9592014451430998 0.9437953915486073 0.9393401173671557 0.9609438178873654 1.0 14.3018143970222 -6.767324711223147 9.01754751854362 0.955701808054943 1.0559303101524458 0.28541331959714866 0.06738175431058664 0.15032952551775045 123.45774570577171 0.02354611807283021 0.021791758003928793 1.70873725685582e-07 6.767324711223147 0.10022850209750278 ATGSAGLLGDPECEGSPPEHS(ph)PEQGR ddPTM_PC-9_Lapatinib_30min_R1 1 ATGSAGLLGDPECEGSPPEHSPEQGR 26 0 Q5TH69 Q5TH69 ARFGEF3 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 1 ATGSAGLLGDPECEGS(0.418)PPEHS(0.582)PEQGR 134.05 3.4759e-10 3908200.0 16627.0 22071.0 26429.0 20539.0 19926.0 23364.0 20375.0 17879.0 27950.0 19194.0 True False 16389.895930981646 22019.895955538206 24256.109638890255 22049.506576095453 18753.991856023276 22364.776184144128 21429.917804359327 18709.72361049844 24801.976673451907 22511.657325602635 0.7280626074714333 0.9781552569430263 1.0774910655424577 0.9794706030381168 0.8330791280610982 0.9934753297221054 0.9519475840629007 0.8311126693111025 1.1017392595632876 1.0 14.458384652574823 -4.75963241530304 24.978025553810202 0.9658121704655731 0.7280623065355641 0.4345165476282913 0.08317184650984265 46.11969072178244 637339.6277590991 0.02056565495196857 0.12904282658273777 1.739272317400155e-05 4.75963241530304 -0.23774986393000896 ATHGSNS(ph)LPSSAR ddPTM_PC-9_AZD4547_30min_R2 2 ATHGSNSLPSSAR 13 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;A0A0J9YYG8;Q8TDM6-5 Q8TDM6-4 DLG5 Disks large homolog 5 1 ATHGS(0.005)NS(0.994)LPS(0.001)SAR;ATHGS(0.001)NS(0.999)LPSSAR 129.36 5.307e-05 29087000.0 9104.0 10415.6 51884.0 121940.0 88737.0 72870.0 24943.0 86515.0 44300.0 67020.0 True False 11998.8826250363 13782.239011840791 51195.984259596626 93828.6169542198 76417.39926211527 68313.42738049354 27162.878679006335 73146.09466692242 46641.60755975754 64673.65019930031 0.18552969544876738 0.21310439366525655 0.7916049906233761 1.4508013180804649 1.1815847571093492 1.0562791364021789 0.4199991587810549 1.1310030351080103 0.721184089904085 1.0 15.980890418353598 -5.329006800705607 3.8458238882307376 0.9934224866170783 0.18745874288914843 0.5897375061005746 0.26055847407146293 0.15537120009994032 4.496850490889669 0.07340655194093205 0.17403729680039917 4.688060409586582e-06 5.329006800705607 -0.8059637437279299 ATHGSNS(ph)LPSSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATHGSNSLPSSAR 13 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;A0A0J9YYG8;Q8TDM6-5 Q8TDM6-4 DLG5 Disks large homolog 5 1 ATHGSNS(0.998)LPS(0.001)SAR;ATHGS(0.008)NS(0.992)LPS(0.001)SAR 100.58 0.0012577999999999999 16148700.0 14090.900000000001 23593.8 76511.0 62997.0 102295.0 91272.0 55026.0 52846.0 61657.0 46173.0 True False 16476.211062039034 25936.036538007917 78335.31240958345 59467.4823290297 82251.02908080195 86485.53564482684 49813.538926259105 51458.84849496536 62558.616981415966 54543.799394733134 0.30207303570477 0.4755084322290969 1.4361909745720367 1.0902702596616693 1.5079812919806295 1.5856162681101762 0.9132759264854073 0.9434408505824465 1.1469427813174444 1.0 15.735127578097927 -5.175476798907838 5.336791574244729 1.210259371107162 0.3543963223277454 0.6755844364084108 0.22624416679361453 0.131809828845629 6.147036656842974 0.06228655307728244 0.17337290823334178 6.676105654297119e-06 5.175476798907838 -0.8558630487794167 ATHGSNS(ph)LPSSAR ddPTM_PC-9_Lapatinib_30min_R1 2 ATHGSNSLPSSAR 13 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;A0A0J9YYG8;Q8TDM6-5 Q8TDM6-4 DLG5 Disks large homolog 5 1 ATHGSNS(0.981)LPS(0.014)S(0.004)AR;AT(0.01)HGS(0.048)NS(0.807)LPS(0.057)S(0.079)AR 88.28299999999999 0.0037855 11409400.0 41569.0 26945.0 89683.0 31567.0 58547.0 73658.0 29245.0 52065.0 93750.0 32338.0 True False 40976.21843717903 26882.610507995854 82309.6099263912 33888.542484425016 55103.38056783074 70507.81904518438 30759.163003116013 54484.12997262722 83190.88776873417 37927.58021232355 1.0803805095866597 0.7087879152190435 2.1701782572368513 0.8935065800325918 1.4528577952865651 1.8590117969686546 0.8109972434550847 1.4365306109068372 2.1934140618257403 1.0 15.210959709867542 -5.205169497855838 24.99997526790543 1.4608022550618374 0.8945837507460294 0.19553899887745652 0.47165762925376037 469.8249498354094 208735.1032935505 0.11529277647762198 0.30503579088944216 6.2349144973010836e-06 5.205169497855838 -0.566218504315808 ATIAGGGVIPHIHK ddPTM_PC-9_AZD4547_30min_R2 1 ATIAGGGVIPHIHK 14 0 Q71UI9;P0C0S5;Q71UI9-3;Q71UI9-4 Q71UI9 H2AFV;H2AFZ Histone H2A.V;Histone H2A.Z 0 94.12200000000001 0.0014824000000000003 4915700.0 49307.0 46556.0 69984.0 96865.0 76091.0 70095.0 51694.0 70081.0 55333.0 68612.0 False True 64985.60035068816 61604.316547799426 69055.96643326677 74534.27079933167 65527.078076265985 65711.94856917363 56294.66585545251 59251.59175117142 58257.78941544162 66209.91476386729 0.9815085940293753 0.9304394480419831 1.0429852791617347 1.1257267293750879 0.989686791018587 0.9924789784661464 0.8502452549021281 0.8949051205168863 0.879895248668023 1.0 16.01475965261846 -7.117685778407591 4.974213717051914 0.8979970542044045 1.015015210788848 0.4263055431021484 0.05923083595856378 0.22027073259507446 8.078627555231217 0.024239507409460927 0.01870453941741683 7.626305904364955e-08 7.117685778407591 0.11701815658444348 ATIAGGGVIPHIHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATIAGGGVIPHIHK 14 0 Q71UI9;P0C0S5;Q71UI9-3;Q71UI9-4 Q71UI9 H2AFV;H2AFZ Histone H2A.V;Histone H2A.Z 0 ; 81.565 0.0043201 7209200.0 102795.0 101535.0 120365.0 138824.0 150551.0 129331.0 135760.0 132536.0 133892.0 106945.0 False True 120196.16320620441 111614.72377856176 123234.95808680424 131046.14135348029 121051.61228939651 122548.65468578645 122899.82998271618 129057.07043349955 135849.9172012223 126333.28192384553 0.9514212041024898 0.8834942152919276 0.9754749992253904 1.0373049710881073 0.9581925716326055 0.9700425162678789 0.972822269089795 1.0215603399846442 1.0753295974936632 1.0 16.946875235028422 -4.507207047151159 0.3252520123349317 1.0257082637856176 0.8144111576618835 0.3874750782128924 0.03918466347245686 9.32817652782057 0.6961303048860242 0.042853373774049075 0.8074679266578009 3.110233199562829e-05 4.507207047151159 -0.2112971061237341 ATIAGGGVIPHIHK ddPTM_PC-9_Lapatinib_30min_R1 2 ATIAGGGVIPHIHK 14 0 Q71UI9;P0C0S5;Q71UI9-3;Q71UI9-4 Q71UI9 H2AFV;H2AFZ Histone H2A.V;Histone H2A.Z 0 ; 94.402 0.0014531 13504900.0 183216.0 166396.0 169515.0 168195.0 179978.0 179271.0 177721.0 163734.0 173345.0 142019.0 False True 180603.30624230017 166010.72028533983 155578.13104682276 180564.62138207201 169392.04789036216 171603.9972311119 186922.5237844684 171341.67938035424 153821.06069622628 166566.79492157733 1.0842695648153131 0.9966615516826189 0.934028484609263 1.0840373164836672 1.0169616817692566 1.030241335386841 1.1222076036972128 1.0286664845837072 0.9234797413773137 1.0 17.345741302651888 -4.748449755506889 24.685533136418815 1.0195311107370173 1.0842697465982463 0.11315029926800435 0.056876468064447114 1372.6510948102916 2608410.613496962 0.014573212196533587 0.2561243716932964 1.7846384453825574e-05 4.748449755506889 0.06473863586122897 ATIS(ph)DEEIER ddPTM_PC-9_AZD4547_30min_R2 2 ATISDEEIER 10 0 C9J0A7;Q9UQN3-2;Q9UQN3 C9J0A7 CHMP2B Charged multivesicular body protein 2b 1 AT(0.007)IS(0.993)DEEIER;AT(0.002)IS(0.998)DEEIER 144.28 0.0001326 592840000.0 29316.0 24007.0 38245.0 51629.0 38661.0 29835.0 33761.0 44096.0 31778.0 29273.0 True False 38637.87818931945 31766.793267527726 37737.84631116093 39726.73171009848 33293.58748743638 27969.412733594352 36765.66359627678 37281.97642527443 33457.720203927194 28248.161180007744 1.3678015338097436 1.124561456057191 1.3359399243965437 1.4063475302673698 1.178610787274871 0.9901321560494821 1.3015241368099097 1.3198018868449477 1.1844211731419334 1.0 14.785869337596703 -6.3729299529423304 12.416104744781821 1.1765815535724031 1.2974384206641545 0.24821401402919407 0.12260111652431321 1.2764951457293208 135.62023333303463 0.039451398547153675 0.04473072617958123 4.237113006422312e-07 6.3729299529423304 0.12085686709175136 ATIS(ph)DEEIER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATISDEEIER 10 0 C9J0A7;Q9UQN3-2;Q9UQN3 C9J0A7 CHMP2B Charged multivesicular body protein 2b 1 AT(0.004)IS(0.996)DEEIER 124.12 0.00042335 195840000.0 28820.0 30482.0 30169.0 26394.0 30623.0 30117.0 25889.0 32953.0 26560.0 20115.0 True False 33698.65677905351 33508.05151148003 30888.34337656964 24915.229750502553 24622.642979044846 28537.611502051604 23436.606499871385 32088.018666589596 26948.38975341662 23761.690269747607 1.4181927462440345 1.4101712096694183 1.299921976337491 1.0485461879041318 1.0362328058115196 1.2009924874066935 0.9863189964103646 1.3504097689314098 1.1341108080903735 1.0 14.53634984435179 -5.568985250820044 3.921130848383859 1.1190763547806188 1.4058091405954038 0.5997350553054712 0.10256639175400306 0.15001499211070504 4.852904584107932 0.028492201773317773 0.054248821280273855 2.697831052582126e-06 5.568985250820044 0.286732785814785 ATKMS(ph)RRMEAQALLQDYIS(ph)T(ph)QSAK ddPTM_PC-9_AZD4547_30min_R2 1 ATKMSRRMEAQALLQDYISTQSAK 24 3 C9J5N1;Q9BTE6;Q9BTE6-2;Q9BTE6-3 C9J5N1 PTGES3L-AARSD1;AARSD1 Alanyl-tRNA editing protein Aarsd1 3 AT(0.109)KMS(0.89)RRMEAQALLQDY(0.148)IS(0.664)T(0.595)QS(0.595)AK 44.729 0.031001 10758000.0 12930.0 8410.2 17899.0 29051.0 21134.0 17830.0 11965.0 17796.0 16403.0 21300.0 True False 17041.47103929255 11128.63267957519 17661.64756500116 22353.74078347579 18199.90889939423 16715.087281380518 13029.861820723676 15046.037111397487 17270.029092611792 20554.29348321542 0.829095441942997 0.5414261837149889 0.8592680443832142 1.0875460546347553 0.8854553387717378 0.8132163382326915 0.63392409140036 0.7320143172852932 0.8402151651047725 1.0 14.327152162262328 -12.025491126686338 1.469011490376114 2.0919428673214977 0.8005676861632667 0.15237738637532383 0.13970595126704716 766296.1194671622 55933.83741203077 2759643.333479278 0.04338535240340168 9.429938780988512e-13 12.025491126686338 -1.291375181158231 ATLLEDQQDPS(ph)PSS ddPTM_PC-9_AZD4547_30min_R2 1 ATLLEDQQDPSPSS 14 0 B5MBZ0;Q9HC35;Q9HC35-2 B5MBZ0 EML4 Echinoderm microtubule-associated protein-like 4 1 ATLLEDQQDPS(0.983)PS(0.01)S(0.007) 106.32 0.00088686 2459200.0 11417.0 10702.0 13390.0 19959.0 15460.0 15181.0 12632.0 14311.0 11568.0 12053.0 True False 15047.368511647574 14161.212210983538 13212.439851129422 15357.76091347606 13313.645859025019 14231.729670142315 13756.223528573464 12099.563784064363 12179.46086345993 11631.028138647674 1.2937264300520481 1.2175374388381495 1.1359649115822374 1.3204130133986323 1.14466629263722 1.2236003129296031 1.182717758446837 1.0402832526782249 1.047152557647928 1.0 13.50569101075162 -7.720839204227829 2.9553782827462203 1.025767957672465 1.2191146109305704 0.7186939547845377 0.05433837736171917 0.13937380287265616 2.4605658685141054 0.031047129963564703 0.014844583131959146 1.9017822767712532e-08 7.720839204227829 0.1933466532581054 ATLLEDQQDPSPS(ph)S ddPTM_PC-9_Lapatinib_30min_R1 2 ATLLEDQQDPSPSS 14 0 B5MBZ0;Q9HC35;Q9HC35-2 B5MBZ0 EML4 Echinoderm microtubule-associated protein-like 4 1 ATLLEDQQDPS(0.122)PS(0.511)S(0.367);ATLLEDQQDPS(0.015)PS(0.565)S(0.421) 111.12 0.00043019999999999994 4019300.0 50799.0 44242.0 59208.0 45984.0 53193.0 51906.0 42839.0 48922.0 77334.0 39792.0 True False 50074.59694460435 44139.56036722035 54340.14678948935 49365.816758127155 50064.292321461726 49686.101378795815 45056.99380716314 51195.094718541586 68623.83055687771 46669.99418049286 1.07295057185875 0.9457802843624484 1.1643486943523653 1.0577635079020664 1.0727297742494173 1.0646262604327392 0.9654381706778973 1.096959526511793 1.4704058091689483 1.0 15.5102076669549 -8.02083346317002 24.789608022140918 1.2513628714814415 1.0499484892568838 0.2710782813240351 0.11981991141980028 764.0065392964831 909080.7520350424 0.07225616545290642 0.02799030631934242 9.531615982775367e-09 8.02083346317002 -0.20141438222455776 ATLPDADKER ddPTM_PC-9_AZD4547_30min_R2 2 ATLPDADKER 10 1 P12814-4;P12814-3;P12814;P12814-2;H9KV75;H7C5W8 P12814-4 ACTN1 Alpha-actinin-1 0 ; 114.5 0.0015592 20643100.0 91450.0 76360.0 91459.0 131087.0 113310.0 100448.0 87121.0 119725.0 94381.0 107046.0 False True 120529.19772183351 101041.87669881362 90246.19390175096 100866.91742396106 97578.86237297073 94166.97068088122 94874.60022425982 101224.25225680287 99369.78697736977 103298.35212226666 1.166806587380716 0.9781557461750966 0.8736460170723069 0.9764620185283528 0.9446313553721923 0.911601867272991 0.9184522141453305 0.9799212686083429 0.9619687529937851 1.0 16.656457714080283 -4.777984591349221 4.0149043058533 0.9429588644143663 1.187341193526044 0.7748265241617346 0.03547388645434074 0.09935057276700499 3.0327278485931064 0.008714583037200286 0.07091308582707566 1.667306367080705e-05 4.777984591349221 0.2443823291116778 ATLPDADKER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATLPDADKER 10 1 P12814-4;P12814-3;P12814;P12814-2;H9KV75;H7C5W8 P12814-4 ACTN1 Alpha-actinin-1 0 ; 96.665 0.0070558999999999995 18973700.0 58854.0 60597.0 57653.0 69763.0 78354.0 62414.0 64019.0 63692.0 52332.0 49129.0 False True 68816.81978051394 66612.66968837852 59027.666170220036 65854.4052846975 63001.096168895354 59140.89996643247 57954.656862577394 62020.15248725228 53097.25649758278 58035.69879504998 1.185767057333744 1.1477878456089183 1.017092365488234 1.1347223631657968 1.0855576391245052 1.019043471420676 0.9986035847908236 1.0686552204062052 0.9149068177001357 1.0 15.824652980329132 -1.5228787452803376 0.2256776701684548 0.9704676185819644 2.1458689272177387 0.6094125699873463 0.04909019008035969 34.92680221312166 0.4526982354607392 0.07319501382547136 15.072124276160501 0.029999999999999995 1.5228787452803376 1.1754013086357742 ATLPDADKER ddPTM_PC-9_Lapatinib_30min_R1 2 ATLPDADKER 10 1 P12814-4;P12814-3;P12814;P12814-2;H9KV75;H7C5W8 P12814-4 ACTN1 Alpha-actinin-1 0 ; 103.26 0.0037601999999999996 24727000.0 106511.0 94144.0 101650.0 93536.0 104229.0 92868.0 84945.0 79115.0 96145.0 86458.0 False True 104992.13360827483 93926.01535218995 93292.72938034737 100414.9494669489 98098.45514209823 88896.25212588154 89343.0364609229 82790.97172350713 85316.13764826604 101402.15010195636 1.0354034258909586 0.9262724237873712 0.9200271324281069 0.9902644999734734 0.9674198726897174 0.8766702879228836 0.8810763516463069 0.8164616986943932 0.8413641876674569 1.0 16.6297287175921 -6.774583677410668 7.05972897809956 0.8711847793488254 0.964284578279321 0.3663171945314233 0.0545374531388296 0.149948190804467 35.30764167955349 0.018477435983996923 0.016945170199526353 1.6804141218025785e-07 6.774583677410668 0.09309979893049558 ATLPS(ph)PDKLPGFK ddPTM_PC-9_AZD4547_30min_R2 1 ATLPSPDKLPGFK 13 1 P22314;P22314-2;Q5JRR6 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 1 AT(0.004)LPS(0.996)PDKLPGFK 71.529 0.012121 10740000.0 66880.0 55566.0 46675.0 66354.0 65542.0 68684.0 61028.0 50626.0 51587.0 55522.0 True False 88146.44880958105 73526.62284764633 46056.059003096794 51057.11045908062 56442.62463727154 64389.17862222872 66459.37377309853 42802.91496974653 54313.78350305219 53578.191679581534 1.6451926809462172 1.3723237112473707 0.8596045808811535 0.9529457575653549 1.0534626658327781 1.2017796159919152 1.2404183808694307 0.7988868908776288 1.0137293141185089 1.0 15.7093582690738 -5.029723469963224 3.7512132173685324 1.0229302142796244 1.6138494444937268 0.7163629874765931 0.1292799873141134 0.1208912462378852 3.5824422131813005 0.03616855591709921 0.13874962219286824 9.338487247102333e-06 5.029723469963224 0.5909192302141024 ATLPS(ph)PDKLPGFK ddPTM_PC-9_Lapatinib_30min_R1 1 ATLPSPDKLPGFK 13 1 P22314;P22314-2;Q5JRR6 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 1 AT(0.002)LPS(0.998)PDKLPGFK 60.968 0.026095999999999998 12492000.0 63043.0 47808.0 43677.0 46546.0 48508.0 49052.0 38299.0 36827.0 41742.0 40445.0 True False 62143.995259329735 47697.30351331478 40086.04565809564 49969.14811290422 45654.85481039734 46954.16030579686 40281.93482155379 38538.11686357327 37040.576397253324 47435.86436042504 1.3100635162279333 1.00551142382277 0.8450577679688865 1.0534043974245078 0.9624543670903661 0.9898451506866595 0.8491873261860565 0.8124257327905884 0.7808559387853311 1.0 15.53369061525993 -4.786176877471184 3.0308795497590886 0.9123536402555353 1.3719320556956294 0.6639897230419998 0.08503317525647258 0.2377468028699978 3.2115843550189167 0.023411315929709024 0.2664327218171224 1.636150022011406e-05 4.786176877471184 0.45957841544009403 ATLPSPDKLPGFK ddPTM_PC-9_Lapatinib_30min_R1 1 ATLPSPDKLPGFK 13 1 P22314;P22314-2;Q5JRR6 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 80.014 0.01715 2872300.0 17765.0 17657.0 18397.0 16055.0 22767.0 17828.0 16794.0 12763.0 15845.0 15011.0 False True 17511.667842297993 17616.11630134284 16884.46967447365 17235.73825790996 21427.889821644174 17065.537999097818 17663.51114632691 13356.015573622219 14060.369244752981 17605.63134909977 0.9946628720698174 1.0005955453704083 0.9590380111723176 0.978990069492241 1.217104311498596 0.9693226934443581 1.0032875729406943 0.7586217903117205 0.7986290844078097 1.0 14.103749343636798 -7.6902515102155435 7.445274787403442 0.8345472280780577 1.019849634850108 0.40610307484167274 0.09080045464496365 0.20231010925424445 17.841074357543352 0.04339456557968226 0.024793852626357325 2.0405558682088827e-08 7.6902515102155435 0.18530240677205034 ATLSSIR ddPTM_PC-9_Lapatinib_30min_R1 1 ATLSSIR 7 0 P46779;H0YKD8;P46779-2;P46779-3 P46779 RPL28 60S ribosomal protein L28 0 120.62 0.027533 7659200.0 54195.0 56848.0 57791.0 65160.0 65721.0 72534.0 56834.0 44729.0 64783.0 52820.0 False True 53422.16936185421 56716.371948730724 53039.64705971116 69952.0837673879 61855.419992457435 69431.8899050124 59776.58642910223 46807.272631242515 57486.456344766906 61949.86662177406 0.8623451877308393 0.9155204852175763 0.8561704802939617 1.1291724677063506 0.9984754345010417 1.1207754542704467 0.9649187268482678 0.7555669638002216 0.9279512528371068 1.0 15.918813555792449 -14.503016762672136 14.22085775129441 0.9976848175907221 0.9537035285041995 0.0 0.11055058082561874 0.0 0.0 0.0 0.027101496020351373 3.140387480497204e-15 14.503016762672136 -0.04398128908652266 ATLSSTSGLDLMSESGEGEIS(ph)PQREVSR ddPTM_PC-9_AZD4547_30min_R2 5 ATLSSTSGLDLMSESGEGEISPQREVSR 28 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;H0YDG6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 ATLSSTSGLDLMS(0.001)ES(0.026)GEGEIS(0.974)PQREVSR;ATLSSTSGLDLMS(0.002)ES(0.006)GEGEIS(0.969)PQREVS(0.022)R;ATLSSTSGLDLMSES(0.003)GEGEIS(0.995)PQREVS(0.002)R;ATLSSTSGLDLMS(0.016)ES(0.066)GEGEIS(0.911)PQREVS(0.007)R;ATLSST(0.001)S(0.001)GLDLMS(0.039)ES(0.113)GEGEIS(0.834)PQREVS(0.013)R 93.712 4.415199999999999e-09 38095200.0 92122.6 55308.9 120370.2 258490.3 190491.6 111983.92 82071.7 108327.4 74064.8 130143.7 True False 121415.67053088413 73186.42030051087 118774.01249950852 198899.35497032452 164045.12946436286 104981.54777964856 89375.92230605 91587.88944601016 77979.71412171406 125587.40867565955 0.966782194260021 0.5827528497663423 0.9457477764052986 1.5837523607481978 1.3062227431415814 0.8359241494565158 0.711663081900759 0.7292760509339267 0.6209198433507254 1.0 16.938332302107575 -6.965044855742551 12.086291189640464 0.7472979378952789 1.07061849464496 0.2518229753487592 0.2578038735989052 1.3597165293404774 466.84203576071866 0.10262870098836525 0.09043201968346341 1.0838149673171671e-07 6.965044855742551 0.3233205567496811 ATLSSTSGLDLMSESGEGEIS(ph)PQREVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATLSSTSGLDLMSESGEGEISPQREVSR 28 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;H0YDG6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 ATLSSTS(0.001)GLDLMS(0.034)ES(0.034)GEGEIS(0.911)PQREVS(0.019)R;ATLSSTSGLDLMS(0.005)ES(0.012)GEGEIS(0.981)PQREVS(0.002)R 64.545 0.00050013 19330400.0 49754.0 22316.1 40984.0 71960.0 79598.0 83393.0 59321.0 90953.0 80902.0 57892.0 True False 58176.36951370673 24531.494926033047 41961.21399268556 67928.31449746789 64001.34329902408 79019.72427501374 53701.68543315191 88565.58012266945 82085.03869845302 68387.36132718017 0.8506889048603321 0.3587138683223788 0.6135814158983834 0.9932875487399476 0.9358650788239596 1.1554726303441656 0.7852574568015754 1.295057718325353 1.200295450876371 1.0 16.061442104728062 -5.787796767354426 3.675435410373269 1.0598430673303907 0.5737995190365136 0.5803470783238175 0.17365365823975107 0.15025662352082858 4.28960312614656 0.049459108549885084 0.08189729845358462 1.6300586571859575e-06 5.787796767354426 -0.4860435482938771 ATLSSTSGLDLMSESGEGEIS(ph)PQREVSR ddPTM_PC-9_Lapatinib_30min_R1 2 ATLSSTSGLDLMSESGEGEISPQREVSR 28 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;H0YDG6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 ATLSSTS(0.001)GLDLMS(0.074)ES(0.201)GEGEIS(0.722)PQREVS(0.001)R;ATLS(0.001)S(0.001)T(0.002)S(0.004)GLDLMS(0.058)ES(0.137)GEGEIS(0.792)PQREVS(0.006)R 51.475 0.0057594 11053600.0 13632.599999999999 4795.6 9379.099999999999 4987.0 8303.0 7259.6 1439.7 2477.8 12607.0 2763.79 True False 13438.196624087333 4784.496082840788 8607.98660237298 5353.760616144313 7814.633864326075 6949.123830954143 1514.2406214937982 2592.92763365362 11187.066902404596 3241.5074189813135 4.145662769548886 1.4760096043045243 2.6555504861618218 1.6516268279363688 2.4108023997001764 2.1437938997955452 0.467140877922059 0.799914144410159 3.4511927496745574 1.0 11.662449159544353 -4.756770263124646 24.993040652686627 1.790528733501239 4.145666335706005 0.4011999725088151 0.8655304108883328 148.6394066503106 795547.3065110993 0.21469864377800357 1.6861603513528438 1.7507725826296924e-05 4.756770263124646 2.3551376022047656 ATLTAS(ph)PLGAS ddPTM_PC-9_AZD4547_30min_R2 2 ATLTASPLGAS 11 0 Q13111;Q13111-3 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 ATLT(0.001)AS(0.991)PLGAS(0.008);ATLT(0.013)AS(0.964)PLGAS(0.023) 87.568 0.010302 12251100.0 84309.0 77486.0 136399.0 166621.0 139929.0 130307.0 112799.0 147455.0 111278.0 123475.0 True False 111117.50826386038 102531.83417868336 134590.26013847667 128209.10271878832 120502.27370035643 122158.88269068154 122837.89247938238 124669.21792881063 117159.92790146051 119152.17783286505 0.9325680007269785 0.8605116250791901 1.1295660942703594 1.07601140869307 1.0113308534686218 1.0252341578014126 1.030932834913746 1.0463024696341205 0.9832797858365705 1.0 16.862445795414935 -5.247504902187924 24.997439737538826 1.0392065921604003 0.8965397995569869 0.6411196219321718 0.04227476981761832 481.3633921356383 863527.307103205 0.010876816565640195 0.028459147632163 5.6558137293752435e-06 5.247504902187924 -0.14266679260341342 ATLTAS(ph)PLGAS ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATLTASPLGAS 11 0 Q13111;Q13111-3 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 AT(0.002)LT(0.03)AS(0.965)PLGAS(0.004) 68.355 0.037416000000000005 3802100.0 28171.0 36607.0 38933.0 35077.0 42731.0 40526.0 43767.0 35062.0 33867.0 30938.0 True False 32939.79389738782 40241.10103276523 39861.31037422473 33111.749411168385 34358.1672970501 38400.74521805434 39621.072914360186 34141.65965125978 34362.240804930756 36546.81449492674 0.9013041041363639 1.1010836809963649 1.0906917860038965 0.9060091794256051 0.9401138723545809 1.0507275599460237 1.084118368780409 0.9341897542397073 0.9402253323528584 1.0 15.157458042562933 -7.813503759051026 24.99998329923487 0.9529055453687361 1.0119533807359335 0.09810462403262832 0.07225823508585755 242.78700900693374 116576.66257343254 0.0411317638410646 0.019759096423561717 1.536371495157017e-08 7.813503759051026 0.05904783536719749 ATLTAS(ph)PLGAS ddPTM_PC-9_Lapatinib_30min_R1 2 ATLTASPLGAS 11 0 Q13111;Q13111-3 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 ATLT(0.001)AS(0.999)PLGAS;ATLT(0.01)AS(0.99)PLGAS 97.81299999999999 0.0052349 11968400.0 111339.0 105616.0 121928.0 117671.0 111479.0 100227.0 95634.0 96508.0 115791.0 95315.0 True False 109751.28544292788 105371.4526410275 111903.55049569075 126324.91787894866 104922.0243961466 95940.52485054832 100585.46057924429 100992.11399977538 102749.39824671461 111790.0707507456 0.981762375726879 0.94258328967311 1.001015114707264 1.1300191245125062 0.9385630019868899 0.8582204502264208 0.8997709716412665 0.9034086240535079 0.9191281261089042 1.0 16.77043252742282 -6.507889695882452 24.931493138452616 0.9078637458574588 1.011145019652599 0.40705415807944556 0.05564484869068444 648.3187782662853 1078359.644503648 0.017971207869934863 0.019706637425057162 3.1053481986487943e-07 6.507889695882452 0.1032812737951403 ATNES(ph)EDEIPQLVPIGK ddPTM_PC-9_AZD4547_30min_R2 29 ATNESEDEIPQLVPIGK 17 0 O76021;J3QSV6;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 AT(0.079)NES(0.921)EDEIPQLVPIGK;AT(0.002)NES(0.998)EDEIPQLVPIGK;AT(0.009)NES(0.991)EDEIPQLVPIGK;AT(0.014)NES(0.986)EDEIPQLVPIGK;AT(0.008)NES(0.992)EDEIPQLVPIGK;AT(0.157)NES(0.843)EDEIPQLVPIGK;AT(0.099)NES(0.901)EDEIPQLVPIGK;ATNES(1)EDEIPQLVPIGK;AT(0.003)NES(0.997)EDEIPQLVPIGK;AT(0.003)NES(0.997)EDEIPQLVPIGK;AT(0.013)NES(0.987)EDEIPQLVPIGK;AT(0.013)NES(0.987)EDEIPQLVPIGK;AT(0.285)NES(0.715)EDEIPQLVPIGK;AT(0.227)NES(0.773)EDEIPQLVPIGK;AT(0.001)NES(0.999)EDEIPQLVPIGK;AT(0.007)NES(0.993)EDEIPQLVPIGK;AT(0.003)NES(0.997)EDEIPQLVPIGK;AT(0.047)NES(0.953)EDEIPQLVPIGK;AT(0.002)NES(0.998)EDEIPQLVPIGK;AT(0.001)NES(0.999)EDEIPQLVPIGK;AT(0.013)NES(0.987)EDEIPQLVPIGK;AT(0.014)NES(0.986)EDEIPQLVPIGK;AT(0.006)NES(0.994)EDEIPQLVPIGK;AT(0.439)NES(0.561)EDEIPQLVPIGK;ATNES(1)EDEIPQLVPIGK;AT(0.018)NES(0.982)EDEIPQLVPIGK;AT(0.022)NES(0.978)EDEIPQLVPIGK;AT(0.014)NES(0.986)EDEIPQLVPIGK;AT(0.034)NES(0.966)EDEIPQLVPIGK 203.23 3.8401999999999996e-17 509516700.0 2243273.1 2265849.2 2913659.0 3614755.0 3088092.0 2860519.0 2638008.0 3267271.0 2678724.0 3030305.0 True False 2956587.282820883 2998240.6428038944 2875021.9779090276 2781429.0821580333 2659363.730148015 2681650.2947306363 2872785.601501347 2762389.3413684433 2820315.8819165705 2924214.944303051 1.01107043741121 1.0253147254599255 0.9831773767212766 0.9511712152271183 0.9094282673470983 0.9170496512081033 0.9824125983276645 0.9446601545998266 0.964469416795473 1.0 21.47961792975368 -5.538582286035187 2.8575396895474565 0.948376852528119 1.01778625812738 0.4993142426769056 0.025961435733962337 0.2042491534477319 3.3626072721033635 0.007469072340853365 0.016049254228838995 2.8934615392373325e-06 5.538582286035187 0.06940940559926101 ATNES(ph)EDEIPQLVPIGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 31 ATNESEDEIPQLVPIGK 17 0 O76021;J3QSV6;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 AT(0.014)NES(0.986)EDEIPQLVPIGK;AT(0.053)NES(0.947)EDEIPQLVPIGK;AT(0.003)NES(0.997)EDEIPQLVPIGK;AT(0.002)NES(0.998)EDEIPQLVPIGK;AT(0.025)NES(0.975)EDEIPQLVPIGK;AT(0.169)NES(0.831)EDEIPQLVPIGK;AT(0.013)NES(0.987)EDEIPQLVPIGK;AT(0.001)NES(0.999)EDEIPQLVPIGK;AT(0.011)NES(0.989)EDEIPQLVPIGK;AT(0.011)NES(0.989)EDEIPQLVPIGK;AT(0.011)NES(0.989)EDEIPQLVPIGK;AT(0.477)NES(0.523)EDEIPQLVPIGK;AT(0.017)NES(0.983)EDEIPQLVPIGK;AT(0.003)NES(0.997)EDEIPQLVPIGK;AT(0.002)NES(0.998)EDEIPQLVPIGK;AT(0.003)NES(0.997)EDEIPQLVPIGK;AT(0.004)NES(0.996)EDEIPQLVPIGK;AT(0.364)NES(0.636)EDEIPQLVPIGK;AT(0.006)NES(0.994)EDEIPQLVPIGK;AT(0.002)NES(0.998)EDEIPQLVPIGK;AT(0.098)NES(0.902)EDEIPQLVPIGK;AT(0.003)NES(0.997)EDEIPQLVPIGK;AT(0.002)NES(0.998)EDEIPQLVPIGK;AT(0.001)NES(0.999)EDEIPQLVPIGK;AT(0.001)NES(0.999)EDEIPQLVPIGK;AT(0.212)NES(0.788)EDEIPQLVPIGK;AT(0.023)NES(0.977)EDEIPQLVPIGK;AT(0.036)NES(0.964)EDEIPQLVPIGK;AT(0.05)NES(0.95)EDEIPQLVPIGK;AT(0.023)NES(0.977)EDEIPQLVPIGK;ATNES(1)EDEIPQLVPIGK 230.27 1.9877e-29 438278600.0 2779980.2 2865459.3 3183133.3 3173826.5 3820349.4 3012020.6 3252856.5 3448893.0 3102677.1 2416281.1 True False 3250575.9407482473 3149923.162143221 3259031.2699722606 2996007.290889345 3071779.359677637 2854064.9373767744 2944722.3836783506 3358363.21315419 3148047.882899116 2854333.7361593395 1.1388212596057787 1.1035581166418238 1.1417835373229563 1.049634544459624 1.0761808686782655 0.9999058278367522 1.031667161542446 1.176583932919158 1.1029011229552241 1.0 21.4447225976743 -5.76106154403547 24.999995765666473 1.0664565879971872 1.1256046917150913 0.26436120283202746 0.04981169882210222 16.42404334654484 1086575.8919673983 0.014771737185815956 0.02368209312741453 1.733558317141294e-06 5.76106154403547 0.05914810371790402 ATNES(ph)EDEIPQLVPIGK ddPTM_PC-9_Lapatinib_30min_R1 38 ATNESEDEIPQLVPIGK 17 0 O76021;J3QSV6;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 AT(0.005)NES(0.995)EDEIPQLVPIGK;AT(0.013)NES(0.987)EDEIPQLVPIGK;AT(0.047)NES(0.953)EDEIPQLVPIGK;AT(0.014)NES(0.986)EDEIPQLVPIGK;ATNES(1)EDEIPQLVPIGK;ATNES(1)EDEIPQLVPIGK;AT(0.018)NES(0.982)EDEIPQLVPIGK;AT(0.213)NES(0.787)EDEIPQLVPIGK;AT(0.285)NES(0.715)EDEIPQLVPIGK;AT(0.024)NES(0.976)EDEIPQLVPIGK;AT(0.007)NES(0.993)EDEIPQLVPIGK;AT(0.073)NES(0.927)EDEIPQLVPIGK;AT(0.001)NES(0.999)EDEIPQLVPIGK;AT(0.006)NES(0.994)EDEIPQLVPIGK;AT(0.001)NES(0.999)EDEIPQLVPIGK;AT(0.002)NES(0.998)EDEIPQLVPIGK;AT(0.221)NES(0.779)EDEIPQLVPIGK;AT(0.02)NES(0.98)EDEIPQLVPIGK;AT(0.034)NES(0.966)EDEIPQLVPIGK;AT(0.319)NES(0.681)EDEIPQLVPIGK;ATNES(1)EDEIPQLVPIGK;AT(0.012)NES(0.988)EDEIPQLVPIGK;AT(0.012)NES(0.988)EDEIPQLVPIGK;AT(0.001)NES(0.999)EDEIPQLVPIGK;AT(0.109)NES(0.891)EDEIPQLVPIGK;AT(0.004)NES(0.996)EDEIPQLVPIGK;AT(0.005)NES(0.995)EDEIPQLVPIGK;AT(0.007)NES(0.993)EDEIPQLVPIGK;AT(0.33)NES(0.67)EDEIPQLVPIGK;AT(0.009)NES(0.991)EDEIPQLVPIGK;AT(0.061)NES(0.939)EDEIPQLVPIGK;AT(0.004)NES(0.996)EDEIPQLVPIGK;AT(0.004)NES(0.996)EDEIPQLVPIGK;AT(0.023)NES(0.977)EDEIPQLVPIGK;AT(0.055)NES(0.945)EDEIPQLVPIGK;AT(0.008)NES(0.992)EDEIPQLVPIGK;AT(0.257)NES(0.743)EDEIPQLVPIGK;ATNES(1)EDEIPQLVPIGK 212.85 2.6985e-19 591375140.0 2574906.7 2592077.1 2974400.3 2601854.1999999997 2978360.3 2678005.0999999996 2494283.1 2511831.0 2943505.0 2441142.7 True False 2538188.058277937 2586075.3047316964 2729856.5888511874 2793203.237399178 2803179.0028356425 2563473.0646077916 2623424.8742970624 2628539.8381498987 2611976.4704182167 2863090.9630768113 0.8865202297136524 0.9032459457566724 0.953464847626621 0.9755901134197537 0.9790743776520517 0.8953515964623645 0.9162911371414506 0.9180776552503058 0.9122925202527498 1.0 21.44914207615991 ATNES(ph)EDEIPQLVPIGKK ddPTM_PC-9_AZD4547_30min_R2 1 ATNESEDEIPQLVPIGKK 18 1 O76021;J3QSV6;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 AT(0.281)NES(0.719)EDEIPQLVPIGKK 69.27199999999999 0.0051175 28432000.0 280950.0 133420.0 316400.0 741380.0 538890.0 300600.0 216490.0 291690.0 225970.0 364200.0 True False 370286.25587697193 176545.40582969753 312204.3292679126 570466.2952068181 464074.425418499 281803.43448025733 235757.1906032981 246616.01286938292 237914.3128731019 351449.4688538524 1.0535974263513617 0.5023351049738322 0.8883334787389887 1.6231815545694912 1.3204584628679032 0.8018320112967453 0.6708139049751586 0.7017111554433343 0.6769516927966586 1.0 18.422957749013328 -6.944964885320332 11.109883691014877 0.7373310717944318 1.0652918036529775 0.2257071890796486 0.2833830688978012 0.9752887987900607 193.0207306139935 0.11204695479425551 0.09880316454253082 1.1351025901575242e-07 6.944964885320332 0.3279607318585457 ATNES(ph)EDEIPQLVPIGKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATNESEDEIPQLVPIGKK 18 1 O76021;J3QSV6;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 AT(0.261)NES(0.739)EDEIPQLVPIGKK;AT(0.253)NES(0.747)EDEIPQLVPIGKK 55.302 0.018372 17518200.0 77383.0 48264.0 66323.0 102297.0 107458.0 149466.0 96920.0 147761.0 136100.0 97815.0 True False 90482.41351608232 53055.33095433608 67904.39185137808 96565.63074134893 86402.37629370725 141627.73984014502 87739.0359599648 143882.43031572038 138090.20502409645 115548.08519688604 0.7830715096827998 0.45916235534265604 0.5876721516905593 0.8357181391349557 0.7477612125418046 1.225703910184414 0.7593292074936897 1.245216916148412 1.1950886489274155 1.0 16.818133826844296 -6.409177835691761 1.079637854604372 1.1003670869588342 0.5916141069394505 0.5863169921579997 0.16678018218161272 0.3396653158227138 0.8365128195041003 0.07543099871442255 0.09766804111235264 3.8978234521230126e-07 6.409177835691761 -0.5087529800193837 ATNESEDEIPQLVPIGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATNESEDEIPQLVPIGK 17 0 O76021;J3QSV6;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 0 112.42 0.0037241999999999996 0.0 5988.0 6883.2 7695.9 9024.7 10705.0 5501.4 6157.7 6755.1 6695.9 4890.6 False True 7001.650131609033 7566.518606515956 7879.399442863277 8519.075317472161 8607.432096485489 5212.896899338795 5574.398078112631 6577.785782620073 6793.814870101744 5777.227066031701 1.2119395778602091 1.309714594914355 1.3638722094188918 1.474595895245606 1.48988987244322 0.9023181605564733 0.9648916364891315 1.138571447415562 1.1759646613246801 1.0 12.496161483615722 -6.759292915547605 24.99999998752415 1.040543791775472 1.3721232980941926 0.7195827899559861 0.10412163084347724 34.55520278437758 402467.87971148564 0.038987929910061725 0.037181831620651785 1.7406324852338435e-07 6.759292915547605 0.3315795063187206 ATPAQT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 ATPAQTPR 8 0 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;E5RFR3;E5RG53 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 ATPAQT(1)PR 82.831 0.03891 8729800.0 23895.0 17533.0 33685.0 48263.0 35939.0 36836.0 24257.0 46931.0 33299.0 44624.0 True False 31493.11295312417 23200.199373497875 33238.314890611975 37136.71100591693 30949.49020229626 34532.63909685544 26415.82600796442 39678.89231709348 35059.117158744164 43061.7273424885 0.7313481111114251 0.5387661110056426 0.7718760240678065 0.8624064406555882 0.7187238439401562 0.8019334389956645 0.6134409285969408 0.9214421892905068 0.8141595640115381 1.0 15.394118571290077 -14.522878742267453 0.06696683224567747 1.922137711314575 0.40830683628591324 0.4416285040514921 0.09711309589315303 317.45256007505 1.5318927921494565 45.373918509241875 6.141500626707097 3.000000020812268e-15 14.522878742267453 -1.5138308750286618 ATPAQT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 ATPAQTPR 8 0 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;E5RFR3;E5RG53 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 ATPAQT(1)PR;AT(0.007)PAQT(0.993)PR 98.04 0.013762 19748300.0 124104.0 114072.0 156878.0 103366.0 134096.0 127291.0 123018.0 119616.0 156793.0 110749.0 True False 122334.25420211375 113807.87329256294 143980.09640659209 110967.88045886779 126208.73692287956 121847.06065981387 129387.27010830323 125173.79603967657 139133.32123651332 129891.81708623379 0.9418164819489541 0.8761743106342651 1.108461638588097 0.8543100169674076 0.9716450177849997 0.9380657180191798 0.9961156369257996 0.9636773035254025 1.0711477008913055 1.0 16.9869510213045 -7.857714220426475 1.5597302035990068 1.0294356612971305 0.9503215488864645 0.1679139871818368 0.0676391037661482 0.7281522905252762 3.262126729160289 0.05381093625897271 0.019579140325751306 1.387668658589088e-08 7.857714220426475 -0.07911411241066602 ATPATAPGT(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATPATAPGTSPR 12 0 Q96P47;Q96P47-2;Q96P47-4;H0Y873;Q96P47-5 Q96P47 AGAP3 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 1 ATPAT(0.004)APGT(0.498)S(0.498)PR;ATPAT(0.001)APGT(0.499)S(0.499)PR 98.368 0.0089984 10225500.0 35442.0 47660.0 54943.0 46272.0 62827.0 56264.0 59363.0 51972.0 52978.0 41960.0 True False 41441.630588591775 52391.36982603305 56253.04949248782 43679.52985584805 50516.5003573932 53313.41679288872 53739.70688909827 50607.79006888579 53752.703025470866 49567.01584482275 0.8360727367233735 1.0569805128082024 1.1348887669291357 0.8812216977635613 1.019155571429657 1.0755825398041847 1.0841828174070187 1.0209973145714752 1.084445010644822 1.0 15.597092784303427 -6.52621402402948 22.43854792638114 1.0553079105036511 0.9887336389449828 0.1536491418369157 0.08198359544068341 61.34236858565355 412666.49335572356 0.027146809426056313 0.027329769949538854 2.977048952718989e-07 6.52621402402948 -0.06657427155866835 ATPATAPGT(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 ATPATAPGTSPR 12 0 Q96P47;Q96P47-2;Q96P47-4;H0Y873;Q96P47-5 Q96P47 AGAP3 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 1 ATPAT(0.004)APGT(0.581)S(0.415)PR 80.014 0.036078 2385900.0 31435.0 30689.0 38132.0 31649.0 29188.0 33497.0 35039.0 27021.0 36227.0 26574.0 True False 30986.73113552702 30617.941506026527 34996.934153776645 33976.57303796899 27471.219225815905 32064.41139532082 36853.14797285626 28276.49430501026 32146.733772777905 31167.280492370763 0.9942070865987831 0.9823744973040331 1.122874168066839 1.0901359535133615 0.8814121345152461 1.028784381851014 1.1824306577494725 0.9072493287289496 1.0314256895351166 1.0 14.927744657344466 ATPATAPGTS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 ATPATAPGTSPR 12 0 Q96P47;Q96P47-2;Q96P47-4;H0Y873;Q96P47-5 Q96P47 AGAP3 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 1 ATPAT(0.001)APGT(0.319)S(0.68)PR;ATPAT(0.001)APGT(0.048)S(0.951)PR 119.21 0.00054913 17442600.0 62337.0 55804.0 84586.0 117973.0 80919.0 68655.0 67683.0 96071.0 63931.0 87767.0 True False 82158.8693098514 73841.55169330278 83464.33437248948 90776.14751468075 69684.79361361219 64361.99199681323 73706.65588065515 81225.43444195716 67310.26214227674 84694.30404419555 0.9700636924412166 0.8718597139043786 0.9854775396576345 1.0718093564746873 0.8227801668604415 0.7599329461781464 0.870266976185237 0.959042468777732 0.7947436713943904 1.0 16.369977326633332 -6.286234309837174 24.927956454652325 0.860477051452274 0.9682120354645735 0.2919600473298466 0.08089894912743953 987.4132156466789 992707.643149795 0.02565140583209067 0.029099402599180015 5.173276488917051e-07 6.286234309837174 0.10773498401229942 ATPATAPGTS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATPATAPGTSPR 12 0 Q96P47;Q96P47-2;Q96P47-4;H0Y873;Q96P47-5 Q96P47 AGAP3 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 1 ATPATAPGT(0.232)S(0.767)PR;ATPAT(0.023)APGT(0.339)S(0.638)PR 99.73200000000001 0.0032539 10675000.0 78419.0 77384.0 107703.0 105038.0 113404.0 104860.0 105696.0 104448.0 91271.0 81020.0 True False 91693.78785414994 85066.17210696041 110271.04798590217 99153.06139779047 91183.30027742547 99360.95700451989 95683.70970722708 101706.35067180372 92605.66570723214 95708.28464603303 0.9580548663396248 0.8888067780293906 1.1521578136493407 1.03599246151467 0.9527210796291801 1.038164641357808 0.9997432308091526 1.0626702907481198 0.9675825457506045 1.0 16.5463561914126 -5.2102873349602685 24.999931224067875 1.0255855399274456 0.9234307658936329 0.3595380579694256 0.05482341390561324 377.80409330561935 184645.7766939031 0.013705301546930546 0.036260726395329596 6.161871893934646e-06 5.2102873349602685 -0.10215477403381268 ATPATAPGTS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 ATPATAPGTSPR 12 0 Q96P47;Q96P47-2;Q96P47-4;H0Y873;Q96P47-5 Q96P47 AGAP3 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 1 ATPATAPGT(0.035)S(0.965)PR;ATPATAPGT(0.232)S(0.768)PR 123.95 0.00033685 16372500.0 78906.0 72454.0 87291.0 67319.0 75171.0 62898.0 66811.0 70789.0 80719.0 60851.0 True False 77780.78597041196 72286.23721456047 80114.27093300445 72269.86382960073 70749.58957187226 60207.999162399305 70270.14667126627 74078.11536795 71627.5762112475 71369.01427113921 1.0898397121601495 1.012851837072271 1.1225357636108155 1.0126224183934933 0.9913208175061283 0.8436153949620502 0.9846030155930384 1.0379590656320206 1.0036228879262084 1.0 16.123010226070924 -6.0173844531747545 3.8277122463258855 0.9735535778181412 1.0693653118358961 0.38822901312081415 0.05455724585115799 0.25031771880131737 8.090859630834691 0.01729407764889672 0.02459876069987588 9.607614011026081e-07 6.0173844531747545 0.09581173401775489 ATPELGSSENS(ph)ASSPPR ddPTM_PC-9_AZD4547_30min_R2 1 ATPELGSSENSASSPPR 17 0 Q9BX63 Q9BX63 BRIP1 Fanconi anemia group J protein 1 ATPELGS(0.023)S(0.095)ENS(0.503)AS(0.305)S(0.075)PPR 91.65700000000001 0.0021789 16733000.0 33047.0 33505.0 49107.0 66644.0 47031.0 51002.0 35963.0 52972.0 43218.0 56039.0 True False 43555.25857969844 44334.83602401448 48455.8090940562 51280.25543953596 40501.55746415299 47812.83687745198 39163.63733043757 44786.39457546345 45502.41524870432 54077.09166694406 0.8054290132308031 0.819845051894964 0.8960505752138294 0.948280572397762 0.7489596096180327 0.8841606566404667 0.7242186316461484 0.828195326244592 0.8414360655515573 1.0 15.722729943327392 -8.788142677875985 4.789342937982594 0.9999998830207323 0.8329814311800642 0.38794417017804217 0.06303558158927182 11.776125169781173 212.29782216526064 0.06169881575061558 0.01606160230801737 1.628760851269449e-09 8.788142677875985 -0.1670184518406681 ATPELGSSENSAS(ph)SPPR ddPTM_PC-9_AZD4547_30min_R2 1 ATPELGSSENSASSPPR 17 0 Q9BX63 Q9BX63 BRIP1 Fanconi anemia group J protein 1 ATPELGSSENS(0.002)AS(0.681)S(0.317)PPR 135.57 4.1558000000000004e-05 17436000.0 50453.0 49054.0 67732.0 89894.0 76325.0 76481.0 55926.0 68788.0 52119.0 56752.0 True False 66496.00451240725 64909.746196747 66833.82942469743 69170.32714845521 65728.59121539994 71698.63097965578 60903.30565698219 58158.39519098735 54873.903936952694 54765.12975396438 1.2142033591656685 1.1852386087343885 1.2203719725480868 1.263035940190538 1.2001905502769659 1.309202247885948 1.1120818289045227 1.06196032863005 1.0019861941983337 1.0 15.740969967196953 -7.5956866352348476 2.5447073598401095 1.0172791902497824 1.229141318562659 0.8652382991800824 0.037452806537247356 0.09829923161170831 1.2799584603336478 0.02110580500379251 0.010795394936165213 2.5369585102142676e-08 7.5956866352348476 0.21186212831287654 ATPELGSSENSAS(ph)SPPR ddPTM_PC-9_Lapatinib_30min_R1 2 ATPELGSSENSASSPPR 17 0 Q9BX63 Q9BX63 BRIP1 Fanconi anemia group J protein 1 ATPELGSS(0.001)ENS(0.04)AS(0.616)S(0.343)PPR;ATPELGSSENSAS(0.712)S(0.288)PPR 174.4 6.2104e-06 31235000.0 53874.0 55328.0 59442.0 54114.0 58489.0 50918.0 44119.0 46708.0 64856.0 50659.0 True False 53105.7468807184 55199.89141534218 54554.90821275548 58093.72407901211 55048.792013798346 48740.35583565532 46403.26594407508 48878.22419593725 57551.23431604285 59415.34065112556 0.8938053085068421 0.9290511644032201 0.9181956648719811 0.9777563074177474 0.9265080602168609 0.8203328517772621 0.7809980627149029 0.8226532686724788 0.9686258411606465 1.0 15.858547853065451 -6.676124161715689 8.617023798313639 0.8614414895308722 0.9315414370449845 0.10015089613971129 0.06641489473743963 0.4521636400346763 40.8427188894079 0.02195422995043593 0.021927019027486692 2.108025394249347e-07 6.676124161715689 0.0700999475141123 ATPELGSSENSASS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATPELGSSENSASSPPR 17 0 Q9BX63 Q9BX63 BRIP1 Fanconi anemia group J protein 1 ATPELGS(0.001)S(0.005)ENS(0.068)AS(0.232)S(0.694)PPR;ATPELGSSENSAS(0.376)S(0.624)PPR 153.92 2.585e-05 14599000.0 35407.2 45324.0 46604.0 50597.0 47880.0 42632.0 49820.0 36318.0 41305.0 39857.2 True False 41400.93963592308 49823.46718411919 47715.21610665421 47762.214127687235 38498.257709455895 40396.30287065325 45100.68893443514 35364.690982101805 41909.00748361724 47082.99485057842 0.8793183136992924 1.0582051405658852 1.013427804626324 1.0144259998597025 0.8176679888701459 0.857980742279757 0.9578976247701684 0.7511138808041933 0.8901092128191669 1.0 15.522918469650973 -6.251563023690874 24.772268009605998 0.8695650296547198 0.9976974876556595 0.32860153211421594 0.07765195519265386 627.8610414506228 1574825.2009233343 0.022154377200603616 0.028237802655464456 5.603210991166852e-07 6.251563023690874 0.12813245800093964 ATPGAPALTSMT(ph)PTAVER ddPTM_PC-9_AZD4547_30min_R2 1 ATPGAPALTSMTPTAVER 18 0 P54198;P54198-2 P54198 HIRA Protein HIRA 1 ATPGAPALT(0.14)S(0.14)MT(0.716)PT(0.005)AVER 84.895 0.0072557 5351600.0 3882.3 3695.4 10946.0 18444.0 11855.0 14291.0 8639.4 12738.0 12572.0 14902.0 True False 5116.7906431434985 4889.86578251435 10800.84888801065 14192.020756959399 10209.137882195446 13397.381510836172 9408.28986326453 10769.63479012032 13236.530253753319 14380.285515815785 0.3558198227368941 0.3400395476944013 0.7510872350991652 0.9869081348454919 0.7099398597452874 0.9316492009912744 0.6542491700124498 0.748916617703843 0.9204636611140622 1.0 13.811804699844206 -5.306978239943825 4.22213862501255 0.8311828502863909 0.34140077670121677 0.7561726422022225 0.11193682036951304 0.09270480921109778 3.620350071906736 0.028749008738637883 0.0677915826726097 4.931985147421487e-06 5.306978239943825 -0.48978207358517417 ATPPPS(ph)PLLSELLKK ddPTM_PC-9_AZD4547_30min_R2 1 ATPPPSPLLSELLKK 15 1 Q9H0E9-3;H7C128;H7C179;H7C127;Q9H0E9-4;Q9H0E9-2 Q9H0E9-3 BRD8 Bromodomain-containing protein 8 1 ATPPPS(0.999)PLLS(0.001)ELLKK 69.935 0.011343 1427500.0 4188.7 2788.2 4693.1 6587.1 7723.9 5359.8 3321.1 5187.9 4863.0 5946.5 True False 5520.619469627589 3689.4311237772663 4630.866427582937 5068.545864680509 6651.569809218848 5024.650858706857 3616.6714661767965 4386.229261082213 5120.048251988736 5738.314844973736 0.9620628387902366 0.6429467924732095 0.8070080768815208 0.8832812422483429 1.1591503758363908 0.8756317829280513 0.6302671714405294 0.7643758454494994 0.8922564185326033 1.0 12.48641141150359 -12.315085844445512 1.3836983682466377 2.977000380394565 0.8415752493141803 0.09028550193757923 0.14563562844899394 1066871.690235477 35335.63528304219 6592816.520692194 0.04338514241097686 4.840766735271345e-13 12.315085844445512 -2.135425131080385 ATPPPSPLLSELLKK ddPTM_PC-9_AZD4547_30min_R2 1 ATPPPSPLLSELLKK 15 1 Q9H0E9-3;H7C128;H7C179;H7C127;Q9H0E9-4;Q9H0E9-2 Q9H0E9-3 BRD8 Bromodomain-containing protein 8 0 82.48299999999999 0.0049039999999999995 1647000.0 5937.3 3455.8 10287.0 12092.0 10197.0 8794.4 7087.7 9367.3 6076.6 7946.3 False True 7825.237896488137 4572.819768147718 10150.587658593598 9304.376219537686 8781.322563032223 8244.484777755066 7718.491569305745 7919.799024139904 6397.796670375232 7668.102455665479 1.020492089370371 0.5963430711295659 1.3237417884386726 1.2133870502295214 1.145175434705395 1.07516622598903 1.0065712624383412 1.0328238400477372 0.8343389655218159 1.0 12.904653898049608 -8.107112182373163 6.268657534950315 0.9181120265964241 1.0550450404096514 0.08077647905594709 0.18262814761898222 0.6742725569494125 33.453731869425795 0.13267920046850717 0.04919367735154842 7.814259288064298e-09 8.107112182373163 0.1369330138132273 ATPPPSPLLSELLKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATPPPSPLLSELLKK 15 1 Q9H0E9-3;H7C128;H7C179;H7C127;Q9H0E9-4;Q9H0E9-2 Q9H0E9-3 BRD8 Bromodomain-containing protein 8 0 94.67299999999999 0.0018901 966640.0 4745.2 3826.7 3569.4 4764.7 6763.9 5301.9 4217.5 5405.2 5502.3 4609.8 False True 5548.468638027921 4206.589486220743 3654.50803302488 4497.749306365823 5438.562350062418 5023.859030538473 3817.9878679442054 5263.319227282799 5582.760728171093 5445.520248843279 1.0189051522132362 0.7724862444711861 0.6711035614643357 0.8259540137273792 0.9987222710663248 0.9225673215714562 0.7011245378722466 0.9665411176096201 1.025202455055964 1.0 12.410854170991216 -7.98027052781375 24.64054997522601 1.0070247929292286 0.8425388289931512 0.3012688958723352 0.10809863813495307 244.56571342726966 305443.00948508293 0.06232020140551983 0.029931269176989857 1.0464764808515547e-08 7.98027052781375 -0.1644859639360774 ATPPPSPLLSELLKK ddPTM_PC-9_Lapatinib_30min_R1 1 ATPPPSPLLSELLKK 15 1 Q9H0E9-3;H7C128;H7C179;H7C127;Q9H0E9-4;Q9H0E9-2 Q9H0E9-3 BRD8 Bromodomain-containing protein 8 0 92.65 0.0022302 1274500.0 6152.2 4483.5 4778.7 3448.6 4280.1 3577.1 3937.9 3941.5 4009.1 3283.6 False True 6064.468499824694 4473.118731215418 4385.813732315444 3702.221548192357 4028.352933000363 3424.1157716273738 4141.7851937073165 4124.636479153178 3557.552940305405 3851.1658848780226 1.574709758319531 1.1614972880756846 1.138827530005074 0.9613248711849807 1.0460086772211197 0.8891114727289462 1.0754626826048805 1.0710098194806317 0.9237599850669852 1.0 11.911079551691182 ATPS(ph)ENLVPSSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATPSENLVPSSAR 13 0 Q8N684-2;Q8N684;Q8N684-3;F5H669;F5H6M0;F5H047 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 1 AT(0.063)PS(0.896)ENLVPS(0.02)S(0.02)AR 98.25299999999999 0.0028057 4688800.0 3340.0 10852.0 8921.1 5297.3 6659.4 6576.4 5398.8 2384.3 7873.5 8784.8 True False 3905.3960319930184 11929.314841630518 9133.81285746015 5000.509455078322 5354.538374902894 6231.522006909455 4887.386580072834 2321.7146513746707 7988.635042301426 10377.414699561457 0.376336124657142 1.1495459309470057 0.880162653405972 0.48186466474059675 0.5159799940469926 0.6004888681159475 0.4709637921937697 0.2237276545836397 0.769809752581153 1.0 13.341159452852045 -5.759507403074893 24.999999640980622 0.5416526732597651 0.8367680573997711 0.11459664511926992 0.2622245735357469 77.94908599775603 1008637.4711550261 0.06884545422293413 0.11193200261372599 1.739773041249098e-06 5.759507403074893 0.29511538414000604 ATPVQLPS(ph)PPCTSSPVVPSHPPVQQVK ddPTM_PC-9_AZD4547_30min_R2 2 ATPVQLPSPPCTSSPVVPSHPPVQQVK 27 0 Q14686 Q14686 NCOA6 Nuclear receptor coactivator 6 1 ATPVQLPS(0.994)PPCT(0.005)S(0.001)SPVVPSHPPVQQVK;AT(0.004)PVQLPS(0.768)PPCT(0.075)S(0.075)S(0.075)PVVPS(0.002)HPPVQQVK 164.55 3.5533e-30 11315000.0 55756.0 50960.0 77013.0 117255.0 98943.0 86752.0 62311.0 85448.0 70122.0 80232.0 True False 73485.24820315506 67431.82342288556 75991.75730059965 90223.67132169132 85206.47233049895 81327.38372598555 67856.55828759813 72243.97499970187 73828.50576309967 77423.10210072006 0.949138515627516 0.8709522299321357 0.9815126911569836 1.1653326833161366 1.1005303329186353 1.0504278635101238 0.8764381230724033 0.9331061794155361 0.9535720445178733 1.0 16.240476492600322 -10.276243893998958 11.542840809140714 0.9999911989051536 0.9888627086389373 0.0014770866901838708 0.0894035809505576 0.0 0.0 0.09829388198605285 0.023839768104734885 5.293660754602555e-11 10.276243893998958 -0.011128490266216318 ATPVQLPS(ph)PPCTSSPVVPSHPPVQQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATPVQLPSPPCTSSPVVPSHPPVQQVK 27 0 Q14686 Q14686 NCOA6 Nuclear receptor coactivator 6 1 ATPVQLPS(0.537)PPCT(0.303)S(0.08)S(0.08)PVVPSHPPVQQVK 113.08 3.1066e-11 4704900.0 32817.0 27727.0 36262.0 40459.0 43865.0 49654.0 45527.0 40583.0 39646.0 30205.0 True False 38372.269934705015 30479.553318640756 37126.623604400826 38192.2133998478 35269.96813753725 47050.05682912874 41214.35297306364 39517.739251242834 40225.74774713689 35680.927397351545 1.0754280433179895 0.8542253674971221 1.0405173383233473 1.0703817469352734 0.9884823828921891 1.3186332380088608 1.155080766654143 1.1075311695563181 1.127373941242421 1.0 15.122865492962719 -6.184337249079593 1.5314699696430918 1.1418017399792548 0.9779858728926417 0.2583375924855531 0.09917566179017698 0.4736085229730032 2.216944230610346 0.03561226563560115 0.05199039100854971 6.54128017142537e-07 6.184337249079593 -0.1638158670866131 ATPVQLPS(ph)PPCTSSPVVPSHPPVQQVK ddPTM_PC-9_Lapatinib_30min_R1 1 ATPVQLPSPPCTSSPVVPSHPPVQQVK 27 0 Q14686 Q14686 NCOA6 Nuclear receptor coactivator 6 1 AT(0.018)PVQLPS(0.801)PPCT(0.131)S(0.038)S(0.011)PVVPSHPPVQQVK 67.217 0.00018312 11554000.0 22352.0 19880.0 26647.0 22515.0 25411.0 29030.0 21206.0 22801.0 30835.0 25611.0 True False 22033.256381145227 19833.969081423562 24456.18652039458 24170.828207838233 23916.37493994819 27788.45457223524 22303.942918245106 23860.417699142847 27362.037593055094 30037.82722548759 0.7335169822952323 0.6602997258268439 0.8141796121539413 0.8046796469795555 0.796208552649732 0.9251153341962192 0.7425285041695641 0.7943456602246147 0.9109193347326386 1.0 14.874492839392873 -10.894745309169412 0.034603851908981346 1.92686806015841 1.7308259237803109e-10 0.6104026601131037 0.05992118672478538 350.67369217836506 2.036513987926429 70.96981410493858 44.430940677522145 1.2742501425072789e-11 10.894745309169412 -1.9268680599853274 ATQCLVKS(ph)PEVK ddPTM_PC-9_AZD4547_30min_R2 2 ATQCLVKSPEVK 12 1 O43379;O43379-4 O43379 WDR62 WD repeat-containing protein 62 1 ATQCLVKS(1)PEVK;ATQCLVKS(1)PEVK 137.21 0.00031716 20256500.0 43683.0 39207.0 41659.0 61095.0 66305.0 49962.0 48290.0 54674.0 44873.0 52193.0 True False 57573.28533715516 51879.896015327155 41106.57444049297 47010.491658340594 57099.69525761016 46837.868241858276 52587.71644987433 46225.38958353258 47244.89516995484 50365.73895631278 1.1431041523503547 1.0300632352545795 0.8161614480857473 0.9333823474548338 1.1337011317780608 0.929954949782141 1.0441168448950762 0.9177943288716257 0.9380363745071832 1.0 15.620155060781206 -4.889191758254942 4.212498939101558 0.9653938897714108 1.1401900119229469 0.31802708082126463 0.07991691874104612 0.26516360182875126 7.770280732520175 0.020567840264193192 0.1060583564839065 1.2906492748915413e-05 4.889191758254942 0.17479612215153606 ATQCLVKS(ph)PEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATQCLVKSPEVK 12 1 O43379;O43379-4 O43379 WDR62 WD repeat-containing protein 62 1 ATQCLVKS(1)PEVK;ATQCLVKS(1)PEVK 107.69 0.0073444 32677000.0 111263.0 72723.0 72317.0 141670.0 149692.0 141249.0 145488.0 163048.0 150868.0 116842.0 True False 130097.62835558021 79942.45883043658 74041.3115437499 133732.68920033702 120360.92717301307 133841.65378534648 131706.32339809544 158768.1627636363 153074.15908578533 138024.52967923688 0.9425688945140516 0.5791902281153897 0.5364358908943124 0.9689052338097155 0.8720256280005209 0.9696946919246078 0.9542240332510121 1.1502894676229416 1.109035904281095 1.0 17.07456515956892 -6.44335773046562 0.9748018459686832 1.0705033617130246 0.6902636446325839 0.5362346403628819 0.13026584108341038 0.4145574956771058 0.848700816916431 0.06747173829406164 0.08654248111737352 3.6028175493996623e-07 6.44335773046562 -0.3802397170804407 ATQCLVKS(ph)PEVK ddPTM_PC-9_Lapatinib_30min_R1 1 ATQCLVKSPEVK 12 1 O43379;O43379-4 O43379 WDR62 WD repeat-containing protein 62 1 ATQCLVKS(1)PEVK 104.41 0.009234299999999999 7493600.0 32168.0 23045.0 28441.0 25138.0 24522.0 25915.0 23998.0 26076.0 28742.0 22882.0 True False 31709.27842111128 22991.64071838059 26102.690765434865 26986.732377909728 23079.664172106943 24806.675860815587 25240.49901688419 27287.58615511815 25504.77329332219 26837.123211651517 1.181545360545369 0.8567103313218988 0.972633711876473 1.00557470952003 0.8599902452319015 0.9243418404117771 0.9405068798851681 1.0167850682025064 0.9503542198684366 1.0 14.711942410598649 -4.747360269276445 24.993032161820537 0.9468913631926896 1.1815459553713716 0.6374164155721844 0.052969555667796625 476.2895263411905 845454.0272388275 0.013207973080121194 0.27165818460521135 1.789121071693835e-05 4.747360269276445 0.234654592178682 ATRPASTSQPDPS(ph)PDR ddPTM_PC-9_AZD4547_30min_R2 2 ATRPASTSQPDPSPDR 16 1 P20749;H7C0A2 P20749 BCL3 B-cell lymphoma 3 protein 1 ATRPAS(0.002)T(0.002)S(0.002)QPDPS(0.995)PDR;ATRPASTSQPDPS(1)PDR 85.473 0.0099854 0.0 8298.0 8023.3 14142.6 13324.1 13493.1 10612.2 9188.7 17518.7 12421.7 12041.5 True False 10936.591390877775 10616.674820817056 13955.059883389311 10252.434600292921 11619.81597285966 9948.617456391827 10006.476499129427 14811.587454677418 13078.285702596837 11619.930750147354 0.9411924757588668 0.9136607652057155 1.2009589543562766 0.8823146041694705 0.9999901223776491 0.8561683946580892 0.86114768790705 1.2746708885928248 1.1255046164910225 1.0 13.504313850467735 -7.755853271114991 24.99999918248139 1.1500658182368855 0.9545919956605868 0.3525276813995688 0.11265219275088187 139.01297684689808 622145.246974605 0.05477566477568704 0.030485219506872344 1.754473160553366e-08 7.755853271114991 -0.19547382257629864 ATRPASTSQPDPS(ph)PDR ddPTM_PC-9_Lapatinib_30min_R1 1 ATRPASTSQPDPSPDR 16 1 P20749;H7C0A2 P20749 BCL3 B-cell lymphoma 3 protein 1 ATRPASTSQPDPS(1)PDR 111.81 0.0020146 3239800.0 3569.9 6854.3 6780.7 7637.7 7790.9 6401.1 6378.2 5278.8 8347.5 4282.0 True False 3518.9925713605176 6838.429289476937 6223.2170202589305 8199.401936620305 7332.654579498737 6127.339874692904 6708.431987227712 5524.07231920685 7407.316646928084 5022.137994593649 0.70069611292018 1.3616569868925412 1.2391569142381686 1.6326516605969397 1.4600663278054822 1.2200660119831455 1.3357721341885398 1.0999443514203584 1.4749329179927133 1.0 12.294085955123503 -4.759507898366215 24.996088200019834 1.3268875098461657 0.7006953204706388 0.5191717900274646 0.17660684666123358 39.6682406518167 513226.8786177635 0.04302095690234434 0.2718775622274084 1.7397710571253404e-05 4.759507898366215 -0.6261921893755269 ATS(ph)FEESER ddPTM_PC-9_AZD4547_30min_R2 2 ATSFEESER 9 0 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 AT(0.017)S(0.944)FEES(0.038)ER;AT(0.078)S(0.922)FEESER 163.84 0.00031412 396450000.0 145157.0 132663.0 191188.0 275412.0 248368.0 203758.0 194480.0 240619.0 187191.0 192076.0 True False 191313.9065468358 175543.7203836395 188652.72219997988 211920.01847298318 213886.3903437467 191016.98004932876 211788.34324231878 203436.86242455302 197085.53410199942 185351.47770338453 1.032168229340976 0.9470856265012343 1.0178107266124863 1.1433414025007986 1.1539502840437355 1.0305662647859255 1.1426309941873827 1.0975734585192263 1.0633070561077087 1.0 17.49990409143821 -5.598471718455593 6.017492998332177 1.0962619473161084 0.9878439054702483 0.40440427960552705 0.051024611307293195 0.1683938151398803 10.177414289819094 0.013403538582345614 0.023561714578165017 2.5207413266396992e-06 5.598471718455593 -0.10841804184586012 ATS(ph)FEESER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATSFEESER 9 0 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 AT(0.076)S(0.919)FEES(0.005)ER 121.36 0.0016214000000000003 172540000.0 63385.0 58051.0 66880.0 81187.0 61346.0 55831.0 60905.0 63445.0 51626.0 47489.0 True False 74114.82858918469 63813.91963430639 68474.67284381227 76638.35560180517 49325.6916759457 52903.124075141706 55135.637485985 61779.63597553411 52380.93258320354 56098.379777282826 1.3211580955355446 1.1375358769300496 1.2206176562614603 1.3661420509124946 0.8792712351368169 0.9430419253670665 0.9828383226909577 1.1012730888272806 0.9337334302908927 1.0 15.775671483341908 -6.26379434541848 24.999937094386247 0.9773813651127532 1.2496081857096084 0.7657444192152909 0.0779106511573528 108.71138421155429 1154060.2047280779 0.024491155205763185 0.02911534934526073 5.447605561483095e-07 6.26379434541848 0.2722268205968552 ATS(ph)FEESER ddPTM_PC-9_Lapatinib_30min_R1 2 ATSFEESER 9 0 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 AT(0.006)S(0.972)FEES(0.022)ER;AT(0.137)S(0.827)FEES(0.036)ER 163.84 0.0001467 310280000.0 142892.0 136493.0 175608.0 160753.0 157379.0 163584.0 153281.0 169318.0 199501.0 207575.0 True False 140854.33387681615 136176.95884460496 161170.18810648334 172575.31187628754 148122.27663901894 156587.89365292888 161217.14017030672 177185.13240574847 177031.09654133557 243454.06217369827 0.5785663735457417 0.5593538166039972 0.6620147828607292 0.7088619115057503 0.6084198198070627 0.6431927742540907 0.6622076408619644 0.7277969848756576 0.7271642746919064 1.0 17.8932900474569 -14.52287874528007 0.1533508263480592 2.2970274014264622 0.5478514543649292 0.9029050396637335 0.03675078285022888 40.92801797577814 0.3674123317951334 16.038851227100597 0.19101929989916258 3.000000000001854e-15 14.52287874528007 -1.749175947061533 ATS(ph)FSSAGEVPKPRPPSTR ddPTM_PC-9_AZD4547_30min_R2 1 ATSFSSAGEVPKPRPPSTR 19 2 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-4 O15231-7;O15231-3;O15231-4 ZNF185 Zinc finger protein 185 1 AT(0.349)S(0.568)FS(0.061)S(0.021)AGEVPKPRPPSTR 43.37 0.034776 391950000.0 22576.0 24112.0 27280.0 28233.0 29853.0 27313.0 21209.0 32384.0 22975.0 30052.0 True False 29754.698390028516 31905.7324641408 26918.249375564646 21724.318045501786 25708.426250289394 25605.113792279644 23096.559912722798 27379.796910288624 24189.41159560788 28999.888627116903 1.0260280228181915 1.1002018964413103 0.9282190604826744 0.7491172923053244 0.8865008614636621 0.8829383492299723 0.7964361591073807 0.9441345538371005 0.8341208446224551 1.0 14.823759739189153 -5.422487911316502 4.641081201153795 0.8644213445657231 1.0600057613791698 0.5456117802595988 0.06901738318814266 0.14662598323633264 5.117898376954035 0.017335355109749272 0.03732483722692529 3.7801765936099445e-06 5.422487911316502 0.19558441681344674 ATS(ph)FSSAGEVPKPRPPSTR ddPTM_PC-9_Lapatinib_30min_R1 1 ATSFSSAGEVPKPRPPSTR 19 2 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-4 O15231-7;O15231-3;O15231-4 ZNF185 Zinc finger protein 185 1 AT(0.146)S(0.403)FS(0.403)S(0.047)AGEVPKPRPPSTR 44.743 0.031160000000000004 234590000.0 18577.0 19408.0 23123.0 27630.0 31053.0 30480.0 28490.0 36479.0 40624.0 30817.0 True False 18312.088573395435 19363.061968423957 21221.91619736122 29662.002370978033 29226.523592546982 29176.441452350336 29965.07279735937 38173.94751313679 36048.497330315244 36143.677388928634 0.5066470789993469 0.535724734372357 0.5871543166180933 0.8206691879134568 0.8086206413932722 0.807235000976617 0.8290543453815282 1.056172206894201 0.9973666194065094 1.0 15.141455678249715 -5.626217713417625 0.38441405010085833 1.0369158011149096 0.2785822661494655 0.8946204347375473 0.060462806945553095 0.9940135176648893 0.18739744650200946 0.061893905719535326 0.32879833204764025 2.3647339504930504e-06 5.626217713417625 -0.7583335349654441 ATS(ph)NVFAMFDQSQIQEFK ddPTM_PC-9_AZD4547_30min_R2 1 ATSNVFAMFDQSQIQEFK 18 0 J3QRS3;P19105;O14950;J3KTJ1;P24844;P24844-2 J3QRS3 MYL12A;MYL12B;MYL9 Myosin regulatory light chain 12A;Myosin regulatory light chain 12B;Myosin regulatory light polypeptide 9 1 AT(0.219)S(0.781)NVFAMFDQSQIQEFK 87.74799999999999 0.0011171 1678800.0 19080.0 18155.0 24046.0 26220.0 24869.0 28282.0 24707.0 27737.0 24959.0 26732.0 True False 25147.04311134586 24023.248709624924 23727.13432862271 20175.3840949618 21416.368620187135 26513.522069097216 26905.875136198898 23450.883982851872 26278.28178519161 25796.12081658754 0.9748381661779043 0.9312736934530631 0.9197946659237841 0.782109226360443 0.8302166349917187 1.0278104315610264 1.043020201661397 0.9090856780207192 1.0186912199718816 1.0 14.654866511110926 -6.76932409304258 24.999937082650238 0.996745538830194 0.8859930390158413 0.46355907121598583 0.060226278282172516 184.49276997392258 584964.6202878207 0.023036273128119695 0.020676658707472432 1.7008887433707075e-07 6.76932409304258 -0.11075249981435276 ATS(ph)NVFAMFDQSQIQEFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATSNVFAMFDQSQIQEFK 18 0 J3QRS3;P19105;O14950;J3KTJ1;P24844;P24844-2 J3QRS3 MYL12A;MYL12B;MYL9 Myosin regulatory light chain 12A;Myosin regulatory light chain 12B;Myosin regulatory light polypeptide 9 1 AT(0.189)S(0.811)NVFAMFDQSQIQEFK;AT(0.183)S(0.817)NVFAMFDQSQIQEFK 153.57 1.3590999999999999e-05 1325000.0 37296.0 34420.0 34731.0 37453.0 45904.0 32858.5 36155.0 33334.0 28813.7 27443.6 True False 43609.47617042263 37836.990126144716 35559.118758050994 35354.629834264306 36909.440724621185 31135.342415916653 32730.136660467735 32459.017820292447 29235.045852335108 32418.907436581943 1.3451864858719174 1.1671272451165005 1.0968635765289731 1.0905558709350474 1.138515873701902 0.9604069007206302 1.0096002379011266 1.0012372527911055 0.901789978873436 1.0 14.984547850343661 -1.5228787527780958 0.3389410714873872 0.9617170767214848 4.93405896332703 0.8308287960182892 0.04945391233138396 23.763611776628643 0.33692458067093384 0.04437057439215832 59.67297968389375 0.029999999482073214 1.5228787527780958 3.972341886605545 ATS(ph)NVFAMFDQSQIQEFK ddPTM_PC-9_Lapatinib_30min_R1 4 ATSNVFAMFDQSQIQEFK 18 0 J3QRS3;P19105;O14950;J3KTJ1;P24844;P24844-2 J3QRS3 MYL12A;MYL12B;MYL9 Myosin regulatory light chain 12A;Myosin regulatory light chain 12B;Myosin regulatory light polypeptide 9 1 AT(0.498)S(0.502)NVFAMFDQSQIQEFK;AT(0.458)S(0.542)NVFAMFDQSQIQEFK;AT(0.179)S(0.821)NVFAMFDQSQIQEFK;AT(0.192)S(0.808)NVFAMFDQSQIQEFK 193.51 1.2151e-14 155504000.0 578079.0 859966.0 1161461.0 901494.0 1044214.0 1055163.0 1019266.0 1033482.0 1136576.0 845564.0 True False 569835.4874532948 857974.8015631555 1065970.1599491136 967792.8760558249 982795.3855237126 1010036.1381950899 1072038.6061731593 1081501.34663153 1008562.8422041255 991718.6107567919 0.5745939233896667 0.865139357330831 1.0748715899721388 0.975874472414399 0.9910022609878523 1.0184704887451086 1.0809907110194032 1.0905324705021153 1.0169848899321146 1.0 19.919571304269255 -4.830110160682299 2.2862666928753104 1.0325513214603192 0.4874286584532508 0.9277085466774069 0.039065537713272355 0.13360569088660154 0.915309928783275 0.011091191571923188 0.14303381227745285 1.4787332534782605e-05 4.830110160682299 -0.5451226630070685 ATS(ph)PEAGGGGGALK ddPTM_PC-9_AZD4547_30min_R2 3 ATSPEAGGGGGALK 14 0 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 AT(0.023)S(0.977)PEAGGGGGALK;AT(0.005)S(0.995)PEAGGGGGALK;AT(0.315)S(0.685)PEAGGGGGALK 155.39 0.00032466 97094000.0 228775.0 196870.0 262900.0 350873.0 285303.0 272147.0 200423.0 262762.0 201034.0 250823.0 True False 301520.69118439 260504.377497321 259413.7742241917 269984.6507838114 245693.6031382544 255129.6050681916 218260.2587292017 222158.17057007362 211660.2468209548 242041.76311457923 1.2457382862545678 1.0762786311963932 1.0717727836967903 1.1154465547997368 1.0150876442837116 1.0540726599624741 0.9017462768434732 0.9178505713698136 0.8744782061464235 1.0 17.884896473341442 -6.4776392018485245 0.6769572444690897 0.9098580236745777 1.1615119504981173 0.7008985561017471 0.05802583725668814 0.4354353371441811 0.44203678086467774 0.03975359293403529 0.05662368647751358 3.3293603118251587e-07 6.4776392018485245 0.2516539268235396 ATS(ph)PEAGGGGGALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ATSPEAGGGGGALK 14 0 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 AT(0.031)S(0.969)PEAGGGGGALK;AT(0.105)S(0.895)PEAGGGGGALK;AT(0.285)S(0.715)PEAGGGGGALK;AT(0.022)S(0.978)PEAGGGGGALK 166.62 6.5758e-05 97289000.0 290502.0 277760.0 295564.0 327219.0 365540.0 305003.0 329636.0 294954.0 284125.0 229623.0 True False 339678.2509239632 305334.17714811035 302611.36669271265 308885.980288311 293915.06105084595 289008.1057529048 298410.49172202917 287211.7700295963 288279.7906133092 271251.8322053326 1.2522615908704098 1.1256483492320821 1.1156104061396404 1.138742465910756 1.083550509728383 1.0654604741402485 1.1001234140831093 1.0588380830260433 1.0627754595039445 1.0 18.049273356895753 -1.5228787452803376 0.2637090752230153 1.0348608281802598 2.280205631476739 0.8042841602310269 0.028024684261988828 23.087563074826704 0.32009995899578486 0.03352354784717702 12.982210202457209 0.029999999999999995 1.5228787452803376 1.2453448032964791 ATS(ph)PEAGGGGGALK ddPTM_PC-9_Lapatinib_30min_R1 2 ATSPEAGGGGGALK 14 0 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 AT(0.015)S(0.985)PEAGGGGGALK;ATS(1)PEAGGGGGALK 180.61 3.2956999999999996e-05 50105200.0 225803.0 183285.0 199659.0 178977.0 176853.0 164496.0 161959.0 160455.0 187014.0 139555.0 True False 222583.00781280137 182860.61484349673 183243.80772602832 192139.56562976976 166450.85424637588 157460.88953890497 170344.44454852684 167910.3250697763 165950.51397527516 163676.8958046512 1.359892651425005 1.1172048073403185 1.119545961726512 1.173895464507641 1.0169477703501624 0.9620227018896726 1.0407360410343642 1.025864550059513 1.0138908925382941 1.0 17.32049116362522 -1.5228787452826167 0.4749794126749795 1.0081519786587307 9.621885635246425 0.8041660703199767 0.04910926420906932 44.2188835627495 0.501926577677927 0.030334430696293258 374.997348410024 0.029999999999842562 1.5228787452826167 8.613733656587694 ATS(ph)PESTSR ddPTM_PC-9_AZD4547_30min_R2 1 ATSPESTSR 9 0 Q8N3X1-2;Q8N3X1 Q8N3X1-2 FNBP4 Formin-binding protein 4 1 AT(0.029)S(0.97)PES(0.001)TSR 104.43 0.0027033 87851000.0 47427.0 25790.0 34147.0 49740.0 37883.0 34721.0 29404.0 37000.0 42697.0 60264.0 True False 62507.79945711739 34126.11314906234 33694.18846874657 38273.21147533941 32623.599358178846 32549.890381200927 32020.899036904226 31282.500175416208 44953.876252346905 58154.17570293397 1.0748634762948548 0.586821371579352 0.5793941374195533 0.6581335048208493 0.5609846406357529 0.5597171654099936 0.5506208049525964 0.5379235419863058 0.7730120100400445 1.0 15.82759516625442 -8.563619046543424 4.652974872881128 0.9998565881941185 0.6281301816839878 0.35055524189285625 0.1510127703006609 0.24121159265466263 18.298373519226583 0.1436110391014966 0.037426087749748586 2.7313726316004876e-09 8.563619046543424 -0.37172640651013067 ATS(ph)PESTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATSPESTSR 9 0 Q8N3X1-2;Q8N3X1 Q8N3X1-2 FNBP4 Formin-binding protein 4 1 AT(0.002)S(0.998)PESTSR;AT(0.002)S(0.997)PES(0.001)TSR 159.34 0.00012666 193452000.0 81919.0 129324.0 145257.0 111622.0 231230.0 221850.0 120718.0 148207.0 226320.0 194016.0 True False 95786.26872599854 142162.43204745866 148720.4777702399 105368.18122340656 185922.14139844346 210215.79545539527 109282.71711736525 144316.72328829704 229629.50184462487 229189.56497018907 0.4179346853704162 0.6202831794106763 0.6488972470870745 0.45974248974691284 0.8112155604581149 0.9172136413921737 0.47682239429870976 0.6296827837998142 1.0019195327435306 1.0 17.80618183393969 -6.703525793287157 0.09275304130698314 1.352179903249217 4.94769811592468e-20 0.45514894695362607 0.1551294574796244 29.698798941744105 1.0908451688050875 5.762812868876116 9.628209042407303 1.9791294747963264e-07 6.703525793287157 -1.352179903249217 ATS(ph)PESTSR ddPTM_PC-9_Lapatinib_30min_R1 2 ATSPESTSR 9 0 Q8N3X1-2;Q8N3X1 Q8N3X1-2 FNBP4 Formin-binding protein 4 1 AT(0.013)S(0.983)PES(0.004)TSR;AT(0.311)S(0.688)PESTSR 136.52 0.00099731 218332000.0 44859.0 68222.0 67502.0 64548.0 94562.0 72439.0 90453.0 82827.0 85499.0 75754.0 True False 44219.30243386692 68064.03615054728 61952.24612525518 69295.07524581587 89000.04907604502 69340.95283355666 95136.21375007178 86675.44479482935 75869.2022756159 88847.97796413994 0.4976962160209694 0.766072990181259 0.6972836922665794 0.779928556998609 1.001711587763612 0.7804449175145377 1.0707752267414554 0.9755477477474227 0.8539215411997061 1.0 16.43905132277805 -4.251937264459855 0.43163688078686224 0.9772506046883149 2.695817518513962e-20 0.6964341829070029 0.09114826934179145 4.637157836360987 0.4774527651133406 0.06473233421246136 2.550790087621621 5.59838466515132e-05 4.251937264459855 -0.9772506046883149 ATS(ph)PLVSLYPALECR ddPTM_PC-9_AZD4547_30min_R2 2 ATSPLVSLYPALECR 15 0 A0A087WXV6;Q96G74-2;Q96G74-3;Q96G74-5;Q96G74;H7BZQ3;Q96G74-4 A0A087WXV6 OTUD5 OTU domain-containing protein 5 1 AT(0.148)S(0.852)PLVSLYPALECR;AT(0.014)S(0.986)PLVSLYPALECR 197.06 9.4611e-10 47795000.0 55466.0 54703.0 76144.0 94668.0 91954.0 70307.0 62730.0 77609.0 67909.0 68446.0 True False 73103.03423552975 72384.67497453104 75134.2808083942 72843.75520602005 79187.77434157734 65910.69217565996 68312.8484758878 65616.31232740212 71498.53110102873 66049.7263733411 1.1067878437878813 1.0959118068920093 1.1375411365628278 1.1028623312423163 1.198911467005547 0.9978950072117596 1.034263913369672 0.9934380644744971 1.0824954928183756 1.0 16.01126496432751 -6.779328008302234 24.999999237740262 1.02199869419309 1.1256866250088218 0.6872134034336665 0.03599724743174195 141.60070273285055 197890.7528506704 0.012214970455755425 0.010794661889876602 1.6621568039522728e-07 6.779328008302234 0.10368793081573169 ATS(ph)PLVSLYPALECR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATSPLVSLYPALECR 15 0 A0A087WXV6;Q96G74-2;Q96G74-3;Q96G74-5;Q96G74;H7BZQ3;Q96G74-4 A0A087WXV6 OTUD5 OTU domain-containing protein 5 1 AT(0.013)S(0.986)PLVS(0.001)LYPALECR;AT(0.007)S(0.993)PLVSLYPALECR 233.52 8.5416e-32 34682200.0 13912.5 18808.1 19273.6 17175.5 23342.0 17193.8 19835.8 20611.0 16999.4 12785.3 True False 16267.611465599646 20675.243869597383 19733.155719535047 16213.212418722309 18768.302661949027 16292.126860044975 17956.80942524426 20069.983089159654 17247.984065294822 15103.17368162089 1.0770988805747341 1.3689337291245725 1.306556895624421 1.0734970517125304 1.2426727691536943 1.0787220754715232 1.1889427880377201 1.3288586566135363 1.1420105753192762 1.0 13.88256411940695 -8.536706988779502 23.04481890234352 0.9999999939178501 1.2101888490786366 0.278994717022921 0.10186116064328371 1064.212823664606 1773515.5832168488 0.09805369557088352 0.02531735535905585 2.9059826110610855e-09 8.536706988779502 0.21018885516078645 ATS(ph)PLVSLYPALECR ddPTM_PC-9_Lapatinib_30min_R1 2 ATSPLVSLYPALECR 15 0 A0A087WXV6;Q96G74-2;Q96G74-3;Q96G74-5;Q96G74;H7BZQ3;Q96G74-4 A0A087WXV6 OTUD5 OTU domain-containing protein 5 1 AT(0.149)S(0.851)PLVSLYPALECR;AT(0.081)S(0.919)PLVSLYPALECR 222.55 4.1448e-19 20594000.0 40629.0 37777.0 44779.0 38124.0 40346.0 45326.0 36061.0 38126.0 47019.0 33407.0 True False 40049.62300955391 37689.52967751195 41097.44347193866 40927.76613793581 37972.927603287935 43387.51264006665 37928.06213217187 39897.4731458059 41723.22508797982 39181.35543797059 1.0221602229396556 0.961925110967118 1.0489030563784731 1.0445724932290825 0.9691580900871141 1.107350987608251 0.968013018136066 1.0182770019013003 1.0648744695428762 1.0 15.25787968654275 -5.270269974776857 24.744543703599792 1.0275292472533144 0.9920426655115202 0.10064306806978074 0.04256813417841535 1142.2120919039037 3200650.6965628145 0.010582946856218344 0.022586620279204 5.366980597226003e-06 5.270269974776857 -0.0354865817417942 ATS(ph)PSSSVSGDFDDGHHSVSTPGPSR ddPTM_PC-9_AZD4547_30min_R2 1 ATSPSSSVSGDFDDGHHSVSTPGPSR 26 0 Q86U86-8;Q86U86;E7EVG2;Q86U86-5;Q86U86-4;Q86U86-7;Q86U86-9;Q86U86-2;Q86U86-6;Q86U86-3;C9JCJ2;C9J053;C9JQF1;C9JPI5;C9J409 Q86U86-8 PBRM1 Protein polybromo-1 1 AT(0.032)S(0.408)PS(0.408)S(0.118)S(0.029)VS(0.003)GDFDDGHHSVSTPGPSR 54.656000000000006 0.0045024999999999996 8102200.0 3707.8 3419.3 10743.0 17405.0 9825.0 10535.0 13677.0 12260.0 7129.2 8554.7 True False 4886.803272968979 4524.521856944122 10600.5408006485 13392.546154569416 8460.968341844813 9876.244784595834 14894.22650414021 10365.498706773045 7506.034957449737 8255.202556848024 0.5919664889282673 0.54808126460699 1.2841042636627884 1.6223158744251234 1.0249255888731765 1.1963661359711992 1.8042230219759838 1.2556322676994092 0.9092490348674943 1.0 13.011087899458396 -5.263026796768978 23.07256836288708 1.2926397458172827 0.5700237268284203 0.5250887042774951 0.2619876166980376 33.27886296773629 483730.99936985085 0.06907297313319528 0.15739291345059533 5.457241878654773e-06 5.263026796768978 -0.7226160189888624 ATS(ph)PVKSTTSITDAK ddPTM_PC-9_AZD4547_30min_R2 3 ATSPVKSTTSITDAK 15 1 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 AT(0.048)S(0.952)PVKSTTSITDAK;AT(0.003)S(0.997)PVKSTTSITDAK;AT(0.141)S(0.852)PVKS(0.001)T(0.002)T(0.002)S(0.002)IT(0.001)DAK 205.66 3.6105e-12 145463000.0 214275.0 71262.0 213512.0 621560.0 444310.0 194010.0 134723.0 182726.0 147632.0 292109.0 True False 282409.99280312494 94296.04789563704 210680.69137373738 478268.9450062716 382625.22584886104 181878.52403032174 146713.08600696668 154489.89532575995 155435.52612329848 281882.3528210597 1.001871844678408 0.3345227076187229 0.7474064596994425 1.6966970093011784 1.3573933310105206 0.6452284870269234 0.5204763070077709 0.5480651547698372 0.5514198550129519 1.0 18.104733635585767 -6.908873794370878 11.523580506087061 0.6124273759741671 1.010531211448241 0.21036826170939704 0.3583260808922741 0.8019857868707063 96.11533922933955 0.14089151787163628 0.12426527569016997 1.2334632245788894e-07 6.908873794370878 0.3981038354740739 ATS(ph)PVKSTTSITDAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ATSPVKSTTSITDAK 15 1 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 AT(0.064)S(0.699)PVKS(0.043)T(0.015)T(0.064)S(0.097)IT(0.017)DAK;AT(0.028)S(0.972)PVKSTTSITDAK;AT(0.002)S(0.995)PVKS(0.002)T(0.001)TSITDAK 167.69 0.00010645 90641000.0 97592.0 18875.8 44948.8 144565.0 117875.0 230319.0 132759.0 233112.0 202440.0 123595.0 True False 114112.39807013847 20749.664678183683 46020.54986127328 136465.491736054 94778.23992276768 218240.66618657278 120183.10642807471 226993.05700258072 205400.30202114664 146001.79512251812 0.781582157769913 0.1421192435392421 0.31520537006175103 0.9346836566053064 0.6491580452365949 1.4947807046032213 0.8231618407651938 1.554727849832931 1.4068340861753377 1.0 17.15562658188754 -6.343808558028839 1.1750545321671664 1.279059309179914 0.39659979854738353 0.5659095261252063 0.2982139640740167 0.3222102043096818 0.9221581455628359 0.12397414631228548 0.16781090630941503 4.5309726634179286e-07 6.343808558028839 -0.8824595106325306 ATS(ph)PVKSTTSITDAK ddPTM_PC-9_Lapatinib_30min_R1 1 ATSPVKSTTSITDAK 15 1 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 AT(0.002)S(0.998)PVKSTTSITDAK 239.33 1.5085999999999997e-31 18154000.0 271900.0 42461.0 71269.0 62800.0 35207.0 45657.0 21078.0 15355.0 63769.0 26932.0 True False 268022.6561396462 42362.68416329608 65409.537926295714 67418.52149465862 33136.193479625195 43704.35654166532 22169.315704553923 16068.449356183433 56586.663702660306 31587.160315365756 8.485177314570599 1.3411362002898535 2.0707634770979038 2.1343647488901523 1.0490399627188363 1.3836114454519384 0.701845796938243 0.5087019281175092 1.7914451042037292 1.0 14.947050624228885 -4.761437209007273 13.445856919740471 1.3369434035621086 8.489609070339354 0.9452312648491207 0.5166115194785889 0.012056687193432794 230.65868578010168 0.1402012521994784 0.7825260010291758 1.7320594365789062e-05 4.761437209007273 7.152665666777245 ATS(ph)SSSGSLSATGR ddPTM_PC-9_Lapatinib_30min_R1 1 ATSSSSGSLSATGR 14 0 Q03252 Q03252 LMNB2 Lamin-B2 1 AT(0.058)S(0.806)S(0.129)S(0.005)S(0.002)GSLSATGR 89.74700000000001 0.0052028 3941600.0 19160.0 22563.0 17990.0 17536.0 24356.0 21218.0 23590.0 20497.0 28957.0 21742.0 True False 18886.774886486335 22510.75675976658 16510.931643408214 18825.65593838114 22923.427965738392 20310.555601573797 24811.374773243504 21449.36544797732 25695.557729271804 25500.075730606048 0.7406556390661143 0.8827721532116242 0.6474855925071328 0.7382588246899187 0.8989552896984115 0.7964900110942175 0.9729921995276296 0.8411490881273372 1.0076659379654755 1.0 14.638213911182898 -7.262508265983254 0.6694737271764297 0.9905742870801402 0.7547076518544553 0.5600365496805804 0.07686310819641438 0.5864202468806361 0.5259675089181092 0.06656079680755593 0.04513721199807207 5.463761505346855e-08 7.262508265983254 -0.23586663522568485 ATS(ph)TATSGFAGAIGQK ddPTM_PC-9_AZD4547_30min_R2 2 ATSTATSGFAGAIGQK 16 0 E7ER27;A0A2R8YD50;P51659-3;P51659;P51659-2;E7EPL9;A0A2R8Y7L2;E7ET17 E7ER27 HSD17B4 Peroxisomal multifunctional enzyme type 2;(3R)-hydroxyacyl-CoA dehydrogenase;Enoyl-CoA hydratase 2 1 ATS(0.999)T(0.001)ATSGFAGAIGQK;AT(0.109)S(0.835)T(0.054)AT(0.002)SGFAGAIGQK 312.67 6.207999999999998e-147 33879000.0 127880.0 133655.0 174629.0 199169.0 195409.0 160368.0 154773.0 192331.0 160328.0 159057.0 True False 168543.17993076053 176856.3649840221 172313.30535943844 153253.6641803756 168279.8333548655 150340.16360854937 168547.49716496977 162610.6632767019 168802.61076390077 153488.4628431829 1.0980837048512162 1.1522453330235893 1.122646628727324 0.9984702520407206 1.096367963022698 0.9794883655988521 1.0981118322695855 1.0594324828364399 1.0997739350374764 1.0 17.22777069208786 -5.658900827747834 8.936974719059261 1.0512492950355123 1.128025532080048 0.3968593869629704 0.043250963570307326 0.26412351300515396 20.882299074889403 0.011119334716910428 0.019281361313578164 2.193305725124075e-06 5.658900827747834 0.07677623704453573 ATS(ph)TATSGFAGAIGQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ATSTATSGFAGAIGQK 16 0 E7ER27;A0A2R8YD50;P51659-3;P51659;P51659-2;E7EPL9;A0A2R8Y7L2;E7ET17 E7ER27 HSD17B4 Peroxisomal multifunctional enzyme type 2;(3R)-hydroxyacyl-CoA dehydrogenase;Enoyl-CoA hydratase 2 1 AT(0.005)S(0.973)T(0.02)AT(0.001)SGFAGAIGQK;ATS(0.995)T(0.005)ATSGFAGAIGQK;AT(0.004)S(0.497)T(0.497)AT(0.002)SGFAGAIGQK 337.22 2.236399999999999e-189 29124700.0 201399.0 222155.0 211699.0 227017.0 271662.0 216384.0 222054.0 191298.0 199093.0 177542.0 True False 235491.87288843136 244209.08022875304 216746.7070329281 214297.9734890443 218431.78124198466 205036.44211773854 201019.43758825952 186276.63019698492 202004.3584780483 209728.95917830127 1.1228390862714754 1.1644032430501812 1.0334610340990662 1.0217853286863388 1.0414955669344865 0.9776258029461092 0.9584724893302057 0.888177917474056 0.9631686500018058 1.0 17.678166555606033 -5.637502428041127 0.6162770292587494 0.943426742204182 1.1873781093791012 0.7592430263399981 0.03755502510026504 0.7011939344792257 0.3999626041163198 0.022485098244449803 0.10660558376183686 2.3040800944349642e-06 5.637502428041127 0.24395136717491916 ATS(ph)TATSGFAGAIGQK ddPTM_PC-9_Lapatinib_30min_R1 1 ATSTATSGFAGAIGQK 16 0 E7ER27;A0A2R8YD50;P51659-3;P51659;P51659-2;E7EPL9;A0A2R8Y7L2;E7ET17 E7ER27 HSD17B4 Peroxisomal multifunctional enzyme type 2;(3R)-hydroxyacyl-CoA dehydrogenase;Enoyl-CoA hydratase 2 1 AT(0.002)S(0.499)T(0.499)AT(0.001)SGFAGAIGQK 166.64 4.831e-05 9768400.0 49209.0 50574.0 59079.0 46268.0 45905.0 50720.0 47992.0 49684.0 55243.0 44127.0 True False 48507.27063617464 50456.89901025729 54221.75267153498 49670.70306552343 43204.95815270243 48550.82383409476 50476.79093334052 51992.50002035936 49020.95160542054 51754.29315446848 0.9372608083236184 0.9749316614113747 1.04767642192894 0.9597407294748231 0.8348091630534055 0.938102346199329 0.9753160145127465 1.0046026493914217 0.9471861872233502 1.0 15.659390922465992 -10.014554805221668 9.36684355059475 1.0000000089784884 0.9586487332508549 0.05608684748786541 0.05189320060624426 0.0 0.0 0.05477135972603302 0.013284005965243257 9.670416843946144e-11 10.014554805221668 -0.04135127572763353 ATSAGS(ph)SPSCSLAGR ddPTM_PC-9_AZD4547_30min_R2 2 ATSAGSSPSCSLAGR 15 0 Q9BXB5-2;Q9BXB5 Q9BXB5-2 OSBPL10 Oxysterol-binding protein-related protein 10 1 ATSAGS(0.729)S(0.27)PS(0.002)CSLAGR;ATSAGS(0.488)S(0.488)PS(0.018)CS(0.006)LAGR 171.11 0.00013367 16861000.0 44954.0 38118.0 50410.0 68988.0 63969.0 59270.0 47663.0 62082.0 47929.0 54023.0 True False 59248.43689871288 50438.89806188287 49741.53046269112 53083.88245397495 55088.00853531509 55563.83753042192 51904.914664534255 52488.653402437565 50462.42909100718 52131.67121332145 1.136515203133807 0.9675288915156433 0.9541518486746772 1.0182655038384838 1.0567090456374664 1.0658364912771765 0.9956503111542441 1.006847702765088 0.9679802683577172 1.0 15.669872489483845 -4.75082711543928 24.98508421656584 1.0061365974844623 1.1365154787392544 0.5674633659311388 0.03473581208285268 387.80605485379016 912974.1230691829 0.009640543986007744 0.1368388206962294 1.7748958933399524e-05 4.75082711543928 0.13037888125479213 ATSAGS(ph)SPSCSLAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATSAGSSPSCSLAGR 15 0 Q9BXB5-2;Q9BXB5 Q9BXB5-2 OSBPL10 Oxysterol-binding protein-related protein 10 1 ATSAGS(0.621)S(0.377)PS(0.002)CSLAGR 180.85 1.865e-05 17417000.0 51076.0 49009.0 51337.0 51606.0 62011.0 55232.0 60855.0 45060.0 47399.0 40250.0 True False 59722.158003016564 53874.2896308026 52561.06877665667 48714.68312890941 49860.38969968817 52335.53668962093 55090.37384795367 43877.22274501643 48092.1207049019 47547.006381175335 1.256065576962624 1.1330742717828046 1.1054548493607472 1.0245583652180545 1.048654657665866 1.1007114994802587 1.1586507341031018 0.9228177772804675 1.0114647454217514 1.0 15.537066889615502 -1.5228787452803394 0.526967010260866 1.0308943679938731 9.412426625704757 0.5720980720273038 0.058796376797336805 98.07839683073813 0.9644289598356097 0.03267974764532807 921.6148583925096 0.029999999999999874 1.5228787452803394 8.381532257710884 ATSAGS(ph)SPSCSLAGR ddPTM_PC-9_Lapatinib_30min_R1 3 ATSAGSSPSCSLAGR 15 0 Q9BXB5-2;Q9BXB5 Q9BXB5-2 OSBPL10 Oxysterol-binding protein-related protein 10 1 ATSAGS(0.615)S(0.38)PS(0.003)CS(0.003)LAGR;AT(0.001)S(0.014)AGS(0.95)S(0.031)PS(0.003)CS(0.002)LAGR;ATSAGS(0.923)S(0.076)PS(0.001)CSLAGR 166.79 1.8487000000000001e-07 34913000.0 133611.0 125960.0 120583.0 114462.0 103028.0 92904.0 77306.0 77919.0 104941.0 55982.0 True False 131705.6826387433 125668.34735895912 110669.13120384062 122879.91731403867 96968.09560084133 88930.71248980156 81308.52641883689 81539.40119729436 93121.43950227964 65658.41410867397 2.005922385221668 1.9139717135257062 1.6855285450645754 1.8715029746325431 1.4768571083722097 1.354445027298537 1.238356538497256 1.2418728399734893 1.4182712264135786 1.0 16.002692283508736 -5.819854493001756 0.3459816307448985 1.0698762142003393 2.343976853509322 0.8766167469199745 0.11157564267619902 1.1008629394543799 0.17978065755239706 0.12382053195593887 0.5540165022493536 1.5140684403555693e-06 5.819854493001756 1.2741006393089827 ATSAGSS(ph)PSCSLAGR ddPTM_PC-9_AZD4547_30min_R2 1 ATSAGSSPSCSLAGR 15 0 Q9BXB5-2;Q9BXB5 Q9BXB5-2 OSBPL10 Oxysterol-binding protein-related protein 10 1 ATSAGS(0.065)S(0.826)PS(0.082)CS(0.027)LAGR 69.878 0.024857 14338000.0 14114.0 15004.0 17368.0 24733.0 24770.0 20356.0 12375.0 26694.0 14796.0 21698.0 True False 18601.958410562656 19853.749580788346 17137.688971950396 19031.18897104081 21331.113061322747 19083.136102062905 13476.351026448436 22569.05566709623 15578.086353367327 20938.359624357203 0.8884152695955869 0.9481998560046151 0.8184828840180223 0.9089149920274644 1.0187576029837917 0.9113959471717091 0.6436201912766676 1.0778807925737444 0.7439974588671039 1.0 14.353860801068194 -7.036695599000784 24.996802055825754 0.8592423458625087 0.9177033176544171 0.03646040599247635 0.12219308958452042 2044.1238204412905 1392438.1875955572 0.044597256730589625 0.03455739997244579 9.189764898809946e-08 7.036695599000784 0.058460971791908456 ATSAGSS(ph)PSCSLAGR ddPTM_PC-9_Lapatinib_30min_R1 1 ATSAGSSPSCSLAGR 15 0 Q9BXB5-2;Q9BXB5 Q9BXB5-2 OSBPL10 Oxysterol-binding protein-related protein 10 1 ATSAGS(0.049)S(0.943)PS(0.007)CS(0.001)LAGR 123.1 3.9751e-05 2597000.0 22716.0 18895.0 17771.0 14098.0 13362.0 18743.0 15691.0 9937.3 19992.0 11832.0 True False 22392.065674395795 18851.249788405345 16309.936978043766 15134.813949549347 12576.07343070275 17941.405582066996 16503.403203347345 10399.023235897208 17740.290434907012 13877.145434851016 1.613593067790472 1.358438583562177 1.175309220085209 1.0906287622769901 0.9062435419260825 1.2928743642773255 1.1892505761235848 0.7493632811385789 1.278381819819666 1.0 13.760423211837061 -4.900755367946591 1.3032312050238555 1.0677775321285956 1.7787210159468287 0.550123504277254 0.15601018266200142 0.8319107972016687 1.4558465495175472 0.04634117693500968 0.7483553043699324 1.2567376672401154e-05 4.900755367946591 0.7109434838182331 ATSDTLES(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATSDTLESPPK 11 0 O94782 O94782 USP1 Ubiquitin carboxyl-terminal hydrolase 1 1 AT(0.003)S(0.052)DT(0.373)LES(0.572)PPK 87.831 0.010159 8158100.0 53121.0 81949.0 52190.0 59683.0 61861.0 41770.0 66167.0 44178.0 42191.0 39653.0 True False 62113.33611242544 90084.35513792651 53434.4075316772 56339.155004896675 49739.781122904154 39579.5076681175 59899.18275240411 43018.374310460196 42807.96355746993 46841.775007024735 1.3260243896203863 1.9231627137190426 1.140742585516108 1.2027544856369692 1.0618679824888106 0.8449617390071548 1.2787556138387408 0.9183762635811484 0.9138843169595972 1.0 15.515508125442219 -5.408664285791387 5.671849345679866 1.0416143600940577 1.6207294951240707 0.6197741363602604 0.1828898488062596 0.13358290708554318 5.720996203674788 0.046438646793233555 0.09840773049020338 3.902435324732371e-06 5.408664285791387 0.579115135030013 ATSDTLES(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 3 ATSDTLESPPK 11 0 O94782 O94782 USP1 Ubiquitin carboxyl-terminal hydrolase 1 1 ATSDT(0.002)LES(0.998)PPK;ATS(0.002)DT(0.01)LES(0.987)PPK;ATSDT(0.012)LES(0.988)PPK 90.434 0.008739499999999999 23379100.0 51419.0 80602.0 64975.0 77599.0 95428.0 84342.0 72432.0 82571.0 73244.0 72218.0 True False 50685.755630910266 80415.37102117209 59633.00631075314 83305.88932267546 89815.11265866655 80734.88927080491 76182.17454750206 86407.55010025529 64994.48942648702 84700.78507556373 0.59840951398139 0.9494052617036723 0.7040431355807742 0.9835314896828423 1.0603811119169697 0.9531775791544229 0.8994270180558303 1.0201505219009352 0.7673422314622442 1.0 16.37008772123648 -4.164318553596897 0.9365184186311564 0.9459976244343152 1.6943517697547346e-10 0.430873980932158 0.10904928875842877 5.705165106228524 1.7512496912490196 0.03545467982893477 7.2361111330741155 6.849856074143712e-05 4.164318553596897 -0.9459976242648801 ATSDTLES(ph)PPKIIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATSDTLESPPKIIPK 15 1 O94782 O94782 USP1 Ubiquitin carboxyl-terminal hydrolase 1 1 AT(0.002)S(0.006)DT(0.061)LES(0.931)PPKIIPK 57.034 0.030285000000000003 8019000.0 67748.0 51088.0 56343.0 76072.0 83895.0 58677.0 63619.0 90980.0 80337.0 68802.0 True False 79216.39831600683 56159.679011170265 57686.4308020174 71809.93246875153 67456.37699529657 55599.874825045 57592.54775832659 88591.8714012782 81511.7766423279 81275.25796366781 0.974668063821079 0.6909812459318816 0.709766197577678 0.8835398898500263 0.8299743204192763 0.6840934894343813 0.7086110730534005 1.0900226418337682 1.0029100944689195 1.0 16.310528609515387 -7.763448559505793 24.999999577509563 1.0348498206902244 0.778586836911301 0.6064480319292851 0.09144345249565199 35.42575806807262 440774.9791941764 0.047515980717312646 0.024624734634966103 1.7240562867030675e-08 7.763448559505793 -0.2562629837789233 ATSDTLES(ph)PPKIIPK ddPTM_PC-9_Lapatinib_30min_R1 1 ATSDTLESPPKIIPK 15 1 O94782 O94782 USP1 Ubiquitin carboxyl-terminal hydrolase 1 1 ATSDTLES(1)PPKIIPK 113.52 0.0044959 0.0 18337.0 9934.3 11722.0 11537.0 10127.0 8565.0 7972.4 10239.0 12028.0 9111.4 True False 18075.511017406043 9911.297738711573 10758.262408228527 12385.469466303783 9531.349770448049 8198.694915990176 8385.171862747211 10714.741319307217 10673.279979544897 10686.293349822648 1.6914668562515203 0.9274776027813295 1.0067347073536095 1.159005191122639 0.8919229014620147 0.7672159698036216 0.7846660753409294 1.0026620988731365 0.9987822372218551 1.0 13.38347390583976 -4.760642005343709 24.998010620758564 0.9446126830296089 1.6914677238106308 0.8062000011303615 0.10923254341737114 9.08370666345015 284602.0291163442 0.03030830217095353 0.1773481006398792 1.7352337844195415e-05 4.760642005343709 0.7468550407810219 ATSEEDVS(ph)IKSPICEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATSEEDVSIKSPICEK 16 1 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 AT(0.001)S(0.007)EEDVS(0.533)IKS(0.46)PICEK 56.347 0.029222 9285900.0 31830.0 49680.0 33174.0 38331.0 40416.0 28205.0 40114.0 30699.0 28085.0 29487.0 True False 37218.19032884362 54611.90207631811 33964.99397309561 36183.43834077869 32496.774928683586 26725.88014793521 36314.11151978988 29893.18377827918 28495.68999340007 34832.75968103642 1.0684823904178307 1.567831621048671 0.9750876555321215 1.0387761024997857 0.9329371323505963 0.7672627834447829 1.0425275474099154 0.8581916578534421 0.8180715583357477 1.0 15.088157156821659 -5.405264908221293 6.766436253091379 0.9223510512361072 1.3162114638572455 0.552001280612181 0.14078934320137837 0.1590899038574992 8.218911768749685 0.03512658889106788 0.07374955199068259 3.933100934505093e-06 5.405264908221293 0.39386041262113836 ATSEEDVS(ph)IKSPICEK ddPTM_PC-9_Lapatinib_30min_R1 1 ATSEEDVSIKSPICEK 16 1 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 AT(0.002)S(0.009)EEDVS(0.58)IKS(0.409)PICEK 58.56399999999999 0.025016 5261700.0 17475.0 32576.0 30779.0 29421.0 29264.0 28841.0 37888.0 38175.0 27792.0 26096.0 True False 17225.803295477483 32500.572273463476 28248.469430375837 31584.7184855789 27542.74905523763 27607.537661654726 39849.6552525922 39948.74986468922 24661.772297265667 30606.65882926571 0.5628122753146247 1.0618791307722497 0.9229517533408448 1.0319557800075185 0.8998940135504628 0.9020108276326045 1.3019929903125673 1.3052306717808322 0.8057649296134338 1.0 14.901557941449877 -7.226592954898667 24.47426313731131 1.1286830582897969 0.9118723139275781 0.2235780592402833 0.18470769694909206 679.8603788242941 477497.9123055544 0.06908332852021264 0.05350876456283823 5.93481307896286e-08 7.226592954898667 -0.2168107443622188 ATSEEDVSIKS(ph)PICEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATSEEDVSIKSPICEK 16 1 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 AT(0.002)S(0.006)EEDVS(0.325)IKS(0.667)PICEK 57.788000000000004 0.026489 6796000.0 29297.0 48243.0 33517.0 42092.0 39153.0 28466.0 50012.0 32569.0 31733.0 28172.0 True False 34256.403457874076 53032.24621312023 34316.172393930356 39733.72170410524 31481.25071216222 26973.19284847097 45274.501304475525 31714.098259707956 32197.035092062106 33279.36059057071 1.0293588233056437 1.5935476304838097 1.0311547994000045 1.1939448654961027 0.9459692179627405 0.8105081458840735 1.3604378359752347 0.9529659734115731 0.9674775753108891 1.0 15.022340094228136 -5.376124876791438 24.406233837663912 1.037538010340242 1.3117855525553404 0.2555768266877637 0.1900845061210851 19.97240334630016 4206.3755838349925 0.04780063820501856 0.09950504437561764 4.206056702769345e-06 5.376124876791438 0.2742475422150983 ATSEVPGSQAS(ph)PNPVPGDGLHR ddPTM_PC-9_AZD4547_30min_R2 2 ATSEVPGSQASPNPVPGDGLHR 22 0 Q96GM8;Q96GM8-2 Q96GM8 TOE1 Target of EGR1 protein 1 1 ATSEVPGS(0.159)QAS(0.841)PNPVPGDGLHR;ATSEVPGS(0.08)QAS(0.919)PNPVPGDGLHR 91.655 0.00011181 18779300.0 62758.0 58027.0 92375.0 126787.0 98268.0 91631.0 79369.0 110244.0 65303.0 83343.0 True False 82713.73855250751 76783.09297016819 91150.04714324721 97558.21598962334 84625.18442915076 85901.29908469852 86432.68724187347 93208.32295509696 68754.78326128332 80425.1869376347 1.0284556580098154 0.954714510389752 1.1333520084190671 1.213030640081376 1.0522224150348936 1.0680895171721545 1.0746967527585265 1.1589444364907087 0.8548911837108798 1.0 16.29535976378382 -8.261770963442693 24.999997002673002 0.9274455901701645 1.084887455460313 0.4147021194673811 0.07507648914807043 30.49183174838914 2298435.1666572657 0.062026693203991075 0.01978062888507763 5.47304522156317e-09 8.261770963442693 0.15744186529014847 ATSEVPGSQAS(ph)PNPVPGDGLHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATSEVPGSQASPNPVPGDGLHR 22 0 Q96GM8;Q96GM8-2 Q96GM8 TOE1 Target of EGR1 protein 1 1 ATSEVPGSQAS(1)PNPVPGDGLHR;AT(0.001)S(0.004)EVPGS(0.345)QAS(0.65)PNPVPGDGLHR 112.55 4.0025e-06 15176400.0 76640.0 87998.0 116121.0 108260.0 112334.0 105402.0 109542.0 101625.0 85928.0 82909.0 True False 89613.63829100147 96733.85988147819 118889.76503134484 102194.5431836558 90322.95909636638 99874.53357038349 99165.38874459824 98957.45143058819 87184.53444019497 97939.74539271712 0.9149874540889424 0.9876874755350488 1.2139072299465625 1.0434430146196303 0.9222298744415858 1.019754882656763 1.0125142591188752 1.0103911444101707 0.8901854307523868 1.0 16.579606825125005 -6.097400526411986 10.842834154948417 0.980509999274416 1.049494616712661 0.12777988624350833 0.08021005079142947 1.1803256788901244 125.58991241155337 0.024807491786074862 0.03204645491526101 7.990969509883905e-07 6.097400526411986 0.06898461743824513 ATSEVPGSQAS(ph)PNPVPGDGLHR ddPTM_PC-9_Lapatinib_30min_R1 2 ATSEVPGSQASPNPVPGDGLHR 22 0 Q96GM8;Q96GM8-2 Q96GM8 TOE1 Target of EGR1 protein 1 1 ATSEVPGS(0.001)QAS(0.998)PNPVPGDGLHR;ATSEVPGS(0.054)QAS(0.946)PNPVPGDGLHR 92.613 0.00010911 14262400.0 75406.0 66568.0 83182.0 67312.0 71876.0 78592.0 71056.0 65392.0 86387.0 61616.0 True False 74330.69661223325 66413.86588592576 76343.09705180566 72262.3490262494 67648.39499365294 75230.80336690012 74734.93200032182 68430.35104523257 76657.18636456136 72266.24350184074 1.0285673228654804 0.9190164407014471 1.0564143554778944 0.9999461093395391 0.9360995080909363 1.0410227475707086 1.034161018739243 0.9469199965193921 1.0607606352557786 1.0 16.141034282534978 ATSGSS(ph)LPVGINR ddPTM_PC-9_Lapatinib_30min_R1 2 ATSGSSLPVGINR 13 0 Q13905-2;Q13905;Q13905-4;Q13905-3 Q13905-2 RAPGEF1 Rap guanine nucleotide exchange factor 1 1 AT(0.258)S(0.017)GS(0.228)S(0.497)LPVGINR;AT(0.006)S(0.001)GS(0.192)S(0.801)LPVGINR 133.98 4.4556000000000005e-05 9496500.0 55567.0 62128.0 71605.0 52516.0 60722.0 68209.0 59848.0 59505.0 81142.0 49966.0 True False 54774.604390260196 61984.146433132926 65717.91330329316 56378.20182824039 57150.45134404529 65291.86007294506 62946.63660148701 62269.81953368253 72002.93349685994 58602.55652449002 0.9346794344606771 1.0577037950081536 1.1214171735977019 0.9620433846547279 0.9752211291355881 1.1141469578321141 1.0741278253821844 1.0625785499248648 1.2286653990388612 1.0 15.83867598284462 -6.772627096661614 24.873545399182706 1.0984539237674016 1.0163532817506211 0.2555483549702333 0.07268673098665719 315.18007917926235 700732.1760159563 0.025573885850467826 0.022755799779545338 1.6880017919884675e-07 6.772627096661614 -0.08210064201678047 ATSLGRPEEEEDELAHR ddPTM_PC-9_AZD4547_30min_R2 1 ATSLGRPEEEEDELAHR 17 1 D6RER6;P36551-2;P36551 D6RER6 CPOX Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial 0 80.53399999999999 0.0025604 4535900.0 10887.0 11515.0 16308.0 25144.0 26888.0 18139.0 12003.0 18824.0 10659.0 15638.0 False True 14348.83953633241 15236.998561902023 16091.745264542085 19347.439270927527 23155.065320663954 17004.76546253287 13071.243747107917 15915.183332487439 11222.412979220218 15090.518379836743 0.9508513342725635 1.009706769401706 1.0663480776142942 1.2820924228009745 1.534411525027708 1.1268509824853898 0.8661891803911198 1.0546478876267482 0.7436731261806812 1.0 13.881354744802683 -7.17907015404289 5.649685501718918 0.9213179164833226 1.1753577130316941 0.3333676298961966 0.17018700412007362 0.2980790030496516 15.772851252389321 0.07260640011891513 0.05577516703147541 6.621095407655596e-08 7.17907015404289 0.2540397965483715 ATSLGRPEEEEDELAHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATSLGRPEEEEDELAHR 17 1 D6RER6;P36551-2;P36551 D6RER6 CPOX Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial 0 55.18600000000001 0.023913 3592600.0 14541.0 16536.0 15644.0 16848.0 22474.0 21212.0 22388.0 20653.0 16537.0 14641.0 False True 17002.504102158808 18177.584797383173 16017.012290200391 15904.06118195298 18070.381030958895 20099.605378408145 20267.246564916386 20110.880633662342 16778.822340069684 17295.297401907774 0.9830709300369319 1.0510131381365018 0.9260905966516436 0.9195598556286559 1.044814703733607 1.162142801672265 1.1718356784475292 1.1627947277416573 0.9701378328550095 1.0 14.078092201387987 -6.513610963912455 6.249044442523508 1.1083136393025361 0.9733060442159204 0.386206382074085 0.07211061052711122 0.1507584788175689 25.529208034138325 0.023724695761950826 0.02528189689098138 3.0647075348054693e-07 6.513610963912455 -0.13500759508661575 ATSS(ph)SSGSLSATGR ddPTM_PC-9_AZD4547_30min_R2 2 ATSSSSGSLSATGR 14 0 Q03252 Q03252 LMNB2 Lamin-B2 1 AT(0.001)S(0.039)S(0.501)S(0.364)S(0.088)GS(0.006)LS(0.001)ATGR;AT(0.001)S(0.032)S(0.895)S(0.068)S(0.004)GSLSATGR 131.79 1.5255e-05 28170000.0 24906.0 24092.0 34601.0 60412.0 47540.0 41051.0 35837.0 49706.0 35709.0 38689.0 True False 32825.5899230178 31879.267855262126 34142.16813210822 46484.94675609582 40939.89160013255 38484.07448053567 39026.42357453193 42025.07983024967 37596.50483863166 37334.50988601509 0.8792291642032172 0.8538820504833676 0.9144935405968013 1.2450932635252925 1.0965696811107188 1.0307909384114131 1.0453176884786322 1.12563630695984 1.007017500789925 1.0 15.18822217153353 -5.573267456246508 11.563401885761383 1.0812292093502343 0.8709442107411516 0.6444078202799872 0.06734874092968401 0.3819435181231944 86.54349291542981 0.018260601195402393 0.03164759906285665 2.6713607691264115e-06 5.573267456246508 -0.21028499860908267 ATSS(ph)SSGSLSATGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATSSSSGSLSATGR 14 0 Q03252 Q03252 LMNB2 Lamin-B2 1 AT(0.001)S(0.006)S(0.496)S(0.496)S(0.002)GSLSATGR 217.2 1.789e-15 71295000.0 24528.0 25954.0 36649.0 42697.0 58106.0 46515.0 44142.0 42672.0 32246.0 26434.0 True False 28680.10594991757 28530.541595989518 37522.8511521065 40304.8255155417 46720.546417411126 44075.671515022404 39960.550199595295 41551.90521472127 32717.536746561447 31226.274948571132 0.9184606872626647 0.9136709915921314 1.201643526610384 1.2907343441355943 1.4961933978471227 1.411493096362403 1.2797091636901707 1.330671214647158 1.0477566344511597 1.0 14.930472856888862 -5.348303514473324 2.958021422730493 1.2938786620143636 0.9053583504947865 0.47315741589761395 0.14285353975206774 0.2058488594874778 3.446363857520223 0.039108521827880265 0.10187047709412671 4.484318857458013e-06 5.348303514473324 -0.3885203115195771 ATSS(ph)SSGSLSATGR ddPTM_PC-9_Lapatinib_30min_R1 1 ATSSSSGSLSATGR 14 0 Q03252 Q03252 LMNB2 Lamin-B2 1 AT(0.008)S(0.039)S(0.916)S(0.028)S(0.008)GS(0.001)LSATGR 97.631 0.0026538 111530000.0 13759.0 13231.0 13924.0 12381.0 19071.0 12963.0 15152.0 18147.0 15473.0 15445.0 True False 13562.794136908422 13200.364432410222 12779.222468194337 13291.540041805245 17949.281275028607 12408.602708228906 15936.496420694606 18990.17586888056 13730.267802086631 18114.647670831135 0.7487197313115688 0.7287121821124862 0.705463484601575 0.7337454353698398 0.990871122706471 0.6850038120371333 0.8797574598349011 1.0483326098281907 0.7579649381862176 1.0 14.144869125252994 -6.6984422292969334 0.31094394926964186 0.9897940346680864 0.6554115857845484 0.3518015364631544 0.1058131700206933 2.633174347577444 0.5152590571788923 0.13952398834314053 0.31504018865673644 2.0024319712984412e-07 6.6984422292969334 -0.33438244888353796 ATSS(ph)TQSLAR ddPTM_PC-9_AZD4547_30min_R2 2 ATSSTQSLAR 10 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 AT(0.003)S(0.046)S(0.902)T(0.046)QS(0.004)LAR;ATS(0.198)S(0.773)T(0.029)QSLAR 150.09 0.00015922 11196600.0 22748.0 22024.7 42858.0 50239.0 51045.0 38623.0 26218.0 47380.0 36070.0 40671.0 True False 29981.390812206268 29143.753558517023 42289.67491708026 38657.17473481259 43958.282850836484 36207.89770436114 28551.351209004028 40058.50968408706 37976.58656163552 39247.12066928895 0.7639131304647998 0.7425704882682552 1.0775229926656027 0.98496842763454 1.1200384155883834 0.9225618870098153 0.7274763274887982 1.020673848194755 0.9676273294451477 1.0 15.260299195375081 -5.2451393350852 24.401201610934834 0.9727973770693409 0.7532417400627596 0.4485659148967861 0.09939223793549429 588.3714911001517 880788.3260700562 0.027042157679570498 0.071039048648686 5.686704545252813e-06 5.2451393350852 -0.21955563700658132 ATSS(ph)TQSLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ATSSTQSLAR 10 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 AT(0.001)S(0.042)S(0.857)T(0.1)QSLAR;AT(0.006)S(0.03)S(0.919)T(0.044)QS(0.001)LAR;AT(0.002)S(0.218)S(0.72)T(0.056)QS(0.004)LAR;AT(0.011)S(0.187)S(0.67)T(0.132)QSLAR 139.76 0.00012173 24697800.0 75641.0 85599.0 93266.0 94908.0 102066.0 92205.0 99408.0 82987.0 87797.0 73002.0 True False 88445.5273221508 94096.70301591672 95489.81515327485 89590.61245588734 82066.89998691174 87369.60748237431 89991.35458840476 80808.6791819946 89080.86502939448 86236.68471648583 1.0256137235902194 1.091144717880467 1.107299236597625 1.0388921228874692 0.9516472050927886 1.0131373645637365 1.043539125886656 0.9370568853343968 1.0329810952526672 1.0 16.39601409573099 -6.006703697270592 8.82034070639379 0.9962970212204092 1.075892503719467 0.4877304689258358 0.036228846197483705 0.10701772408255275 89.04013496795629 0.010237720532724197 0.014276828567923266 9.846826884616695e-07 6.006703697270592 0.0795954824990579 ATSS(ph)TQSLAR ddPTM_PC-9_Lapatinib_30min_R1 1 ATSSTQSLAR 10 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 AT(0.088)S(0.06)S(0.777)T(0.06)QS(0.014)LAR 101.56 0.0035567 7521300.0 32130.0 34921.0 58804.0 29945.0 46977.0 45399.0 34493.0 40302.0 58971.0 35369.0 True False 31671.82030807963 34840.14257003983 53969.362110004266 32147.25519359166 44213.905220335546 43457.39060023793 36278.8787644548 42174.578049684475 52329.06498784016 41482.484523769905 0.7634986349463071 0.8398759854915647 1.30101566310666 0.7749597345156831 1.0658451567673222 1.0476081917257483 0.8745589658128268 1.0166839940726788 1.2614737421972653 1.0 15.3402146840858 -5.021458101763054 24.44614615172462 1.0315661485912426 0.7825928037390433 0.30155055055547875 0.1479775438202385 591.1861187047115 673514.3039623038 0.036212928202660914 0.09806527746945681 9.517916670765612e-06 5.021458101763054 -0.24897334485219935 ATSSHPNS(ph)TSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATSSHPNSTSLK 12 0 A0A3B3IUA7;Q14258 A0A3B3IUA7 TRIM25 E3 ubiquitin/ISG15 ligase TRIM25 1 ATSSHPNS(0.449)T(0.449)S(0.101)LK 95.98100000000001 0.013562000000000001 0.0 5737.5 9791.0 16849.0 20422.0 23855.0 19673.0 15417.0 12691.0 13900.0 12666.0 True False 6708.745429209559 10762.985773535242 17250.74406018832 19277.82154901731 19180.783994550344 18641.3132476628 13956.590150585851 12357.874697226001 14103.261203783546 14962.24553599917 0.4483782473070846 0.7193429453914182 1.1529515418446397 1.288431038150982 1.281945544096397 1.2458900773157204 0.9327871352602982 0.8259371674855187 0.9425898786282508 1.0 13.86903909090711 -5.049516120855104 3.0750713090787594 1.0916658945183138 0.46711115130520897 0.6490241122106566 0.1527845686089134 0.18400025659486197 3.289029961678333 0.04725162992053235 0.2022063219680571 8.922444991779409e-06 5.049516120855104 -0.6245547432131048 ATSSHPNSTS(ph)LK ddPTM_PC-9_AZD4547_30min_R2 2 ATSSHPNSTSLK 12 0 A0A3B3IUA7;Q14258 A0A3B3IUA7 TRIM25 E3 ubiquitin/ISG15 ligase TRIM25 1 ATSSHPNS(0.006)T(0.163)S(0.832)LK;ATSSHPNS(0.017)T(0.367)S(0.616)LK 73.758 0.012412000000000001 14072100.0 17878.199999999997 24695.3 70075.0 103953.0 84328.0 89643.0 51629.0 107562.0 62928.0 90788.0 True False 23563.09571033874 32677.57278208759 69145.75971380844 79988.24190784 72620.51280723547 84037.6090389678 56223.88098137419 90940.76442886794 66254.24560994192 87609.53975371663 0.26895582121054495 0.37299103355581004 0.789249206287208 0.9130083565408376 0.8289110182679018 0.9592289752372852 0.6417552373797173 1.0380235381274217 0.756244648655756 1.0 16.41880035218447 -5.252280836319696 2.922465916414193 0.8702475890526263 0.2815268647711036 0.7990411742474046 0.11057287374541878 0.10208465942071875 1.732932778829789 0.027537289761621696 0.08410410415700988 5.593957515166051e-06 5.252280836319696 -0.5887207242815227 down ATSSS(ph)SGSLSATGR ddPTM_PC-9_AZD4547_30min_R2 2 ATSSSSGSLSATGR 14 0 Q03252 Q03252 LMNB2 Lamin-B2 1 AT(0.008)S(0.12)S(0.019)S(0.384)S(0.384)GS(0.084)LSATGR;ATS(0.258)S(0.148)S(0.457)S(0.133)GS(0.004)LSATGR 179.83 5.4203e-05 30262800.0 25164.0 29862.0 44233.0 58455.0 48814.0 47936.0 35411.0 60530.0 42017.0 39050.0 True False 33165.62855628442 39514.30751676232 43646.441518671214 44979.10287074723 42037.01869097331 44938.55434213437 38562.51039980324 51176.4793410255 44237.932840594396 37682.87138589496 0.8801247711897723 1.0486012892200374 1.1582567865305633 1.1936219618227741 1.115547121143962 1.1925459151436977 1.0233432055880312 1.3580833269563772 1.1739533430871474 1.0 15.20162128017847 -4.839819014556664 1.967869553981279 1.1625152243602772 0.8160063693799706 0.43954753700568017 0.09405082125824168 0.5811453975368941 2.7154164321460237 0.024605076663332885 0.35536084678899477 1.4460422607286441e-05 4.839819014556664 -0.3465088549803066 ATSSS(ph)SGSLSATGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATSSSSGSLSATGR 14 0 Q03252 Q03252 LMNB2 Lamin-B2 1 AT(0.001)S(0.257)S(0.167)S(0.555)S(0.015)GS(0.005)LSATGR;ATS(0.071)S(0.234)S(0.544)S(0.107)GS(0.032)LS(0.01)ATGR 123.95 3.964e-05 31955500.0 21936.4 19969.8 25089.7 28617.0 34869.0 26657.0 30760.0 28196.0 28848.0 23829.0 True False 25649.799256350776 21952.269768189566 25687.933601217122 27013.682267565793 28036.669759210898 25259.059993033465 27846.19011688529 27455.884876131473 29269.847424945896 28149.009069739775 0.9112149984677204 0.7798594157898185 0.9125697298109043 0.959667255093734 0.9960091202411228 0.8973338965664333 0.9892422872825027 0.9753766041322779 1.039818039506443 1.0 14.780796515519775 -5.588253550698414 3.1223157152590884 0.9766372693522668 0.8446095347021451 0.5824560075379135 0.04543358144055745 0.16425736469906782 3.2233472671543786 0.012411253990431699 0.02464634034278509 2.580753050168287e-06 5.588253550698414 -0.13202773465012174 ATSSS(ph)SGSLSATGR ddPTM_PC-9_Lapatinib_30min_R1 2 ATSSSSGSLSATGR 14 0 Q03252 Q03252 LMNB2 Lamin-B2 1 ATS(0.001)S(0.023)S(0.476)S(0.476)GS(0.023)LSATGR;ATS(0.019)S(0.262)S(0.542)S(0.168)GS(0.008)LSATGR 193.45 1.6363e-07 29905200.0 40128.0 31859.0 47312.0 27099.6 39423.0 39377.0 27413.0 36389.0 47591.0 35116.5 True False 39555.76736142607 31785.23244291112 43422.18998960144 29092.5949856155 37104.21664860012 37692.93750227031 28832.311007160868 38079.765784575655 42230.80042455281 41186.34023520503 0.9604098624819015 0.7717420936503098 1.0542861963852097 0.7063651399826948 0.9008864695602253 0.9151805498380103 0.7000454724189294 0.9245726997618993 1.0253593833145436 1.0 15.329878315440077 -8.00197060744828 24.9990088765672 1.0001085118994446 0.8571366425983934 0.25449707488476725 0.10495521714132156 96.67706417325256 1226427.7399541915 0.05559272152111448 0.02606822285492743 9.95472787526628e-09 8.00197060744828 -0.1429718693010512 ATSSSS(ph)GSLSATGR ddPTM_PC-9_AZD4547_30min_R2 4 ATSSSSGSLSATGR 14 0 Q03252 Q03252 LMNB2 Lamin-B2 1 ATS(0.005)S(0.004)S(0.057)S(0.906)GS(0.027)LSATGR;AT(0.07)S(0.258)S(0.008)S(0.04)S(0.312)GS(0.312)LS(0.001)ATGR;ATSSS(0.204)S(0.665)GS(0.13)LSATGR;ATS(0.003)SS(0.064)S(0.895)GS(0.038)LSATGR 250.81 1.3442e-35 96557000.0 83492.5 85997.5 119811.0 187649.0 145013.0 137252.0 108986.2 158020.0 98551.0 114598.0 True False 110041.37824811535 113794.510102229 118222.2278568834 144389.4221981497 124880.44805658465 128669.61074279498 118685.76066575483 133601.63993835883 103760.20466414602 110585.95890091668 0.9950754991120593 1.0290140921433537 1.069052789629547 1.3056759070789483 1.1292613393032618 1.1635257497570823 1.073244395991497 1.2081248041450168 0.9382764837000108 1.0 16.754808692649767 -10.690057851574338 14.579641735883227 0.9999999645853118 1.1091662427480689 0.07736126433516177 0.10164224364406348 0.0 0.0 0.09926951970138546 0.0240763950078321 2.041465986602757e-11 10.690057851574338 0.10916627816275704 ATSSSS(ph)GSLSATGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ATSSSSGSLSATGR 14 0 Q03252 Q03252 LMNB2 Lamin-B2 1 ATSS(0.002)S(0.407)S(0.587)GS(0.004)LSATGR;AT(0.001)S(0.006)S(0.018)S(0.249)S(0.552)GS(0.174)LS(0.001)ATGR;ATSS(0.006)S(0.142)S(0.824)GS(0.027)LSATGR 164.92 0.00031713 55705000.0 40913.0 40251.7 45910.0 45170.0 51577.0 49586.0 54715.0 43183.6 42246.2 39418.3 True False 47838.76283141623 44247.622761782084 47004.66851464457 42639.27134311589 41470.85709859245 46985.62286883585 49531.999097704116 42050.0762568063 42863.97075304176 46564.525754908886 1.027364974856917 0.9502431742712949 1.0094523191764555 0.9157029015509904 0.890610532938168 1.0090433029672288 1.0637281985521434 0.903049597844843 0.9205284507492915 1.0 15.506943664746936 -3.0044642664154093 1.8080855985286293 0.9611899522532837 37.70360523501814 0.1096471527445313 0.053889371074330415 1837.2175359040723 13.841099301450196 0.01541004689596871 278821.1107466581 0.0009897732986889523 3.0044642664154093 36.74241528276485 ATSSSS(ph)GSLSATGR ddPTM_PC-9_Lapatinib_30min_R1 2 ATSSSSGSLSATGR 14 0 Q03252 Q03252 LMNB2 Lamin-B2 1 ATSSS(0.004)S(0.486)GS(0.486)LS(0.024)ATGR;ATSSS(0.022)S(0.841)GS(0.134)LS(0.003)ATGR 169.17 7.9034e-05 50045000.0 53354.0 53195.0 58692.0 39909.0 47821.0 49911.0 44707.0 37363.1 62677.0 41060.0 True False 52593.16217607468 53071.83024579103 53866.570317671765 42844.04099252124 45008.262799703356 47776.42287822364 47021.709706968984 39099.12602670255 55617.65624193011 48157.166290989066 1.0921149691051413 1.102054675001124 1.1185577239363234 0.8896711391537588 0.9346119438951516 0.9920937330393406 0.9764218563617489 0.811906701288165 1.154919621014682 1.0 15.555462881733957 -5.7479776606302595 24.99820389428894 0.958079550457375 1.1040237329154106 0.36671912012061714 0.08303651977026061 229.88517650576057 426889.4387606707 0.021398954889233556 0.03680018002115661 1.7865794710989012e-06 5.7479776606302595 0.14594418245803553 ATSSSSGS(ph)LSATGR ddPTM_PC-9_AZD4547_30min_R2 1 ATSSSSGSLSATGR 14 0 Q03252 Q03252 LMNB2 Lamin-B2 1 ATS(0.002)S(0.001)S(0.019)S(0.298)GS(0.679)LS(0.001)ATGR 122.1 6.2698e-05 19156000.0 5070.7 5770.5 9576.4 18661.0 16866.0 12102.0 9473.2 14655.0 8425.9 13455.0 True False 6683.077122887915 7635.701276722152 9449.4106788914 14358.994759575977 14524.447028351608 11345.260026879812 10316.296447979897 12390.406488397968 8871.275872184216 12983.94454538327 0.5147185510172432 0.5880879458497992 0.7277765740497827 1.105903888405133 1.1186467238506572 0.8737914727858161 0.7945425530678261 0.9542867689467799 0.683249673562307 1.0 13.664441122789546 -5.498360480618974 3.8390683325064785 0.9309069351705143 0.5617755154027719 0.5961873343928568 0.12653509818407563 0.16076903145048405 5.135807102410295 0.03694505356568525 0.07682568504436423 3.1742382407450187e-06 5.498360480618974 -0.36913141976774233 ATSSSSGS(ph)LSATGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATSSSSGSLSATGR 14 0 Q03252 Q03252 LMNB2 Lamin-B2 1 ATSSS(0.006)S(0.053)GS(0.936)LS(0.005)ATGR;ATSS(0.006)S(0.096)S(0.205)GS(0.685)LS(0.008)ATGR 177.36 8.9042e-05 38012000.0 21240.9 17993.7 27511.0 25275.0 24668.7 23303.0 25272.0 25876.0 20383.8 19313.9 True False 24836.564843101936 19779.995619779493 28166.966576048497 23858.92369265561 19835.045320744663 22080.949657413017 22878.05320656454 25196.78241788826 20681.87451263908 22815.357181251722 1.0885897882638067 0.8669597176428819 1.234561718770478 1.0457396525994969 0.8693725530207304 0.9678108250506726 1.002747974744149 1.1043781702700428 0.9064891839446717 1.0 14.47771761933288 -6.027253022602961 24.770270976304598 0.979202054390497 1.0597995709659673 0.14175215986254375 0.10133773228482308 1415.9071875879038 1286917.3834327369 0.03001269975864185 0.038868707314368034 9.391759815103378e-07 6.027253022602961 0.08059751657547032 ATSSSSGS(ph)LSATGR ddPTM_PC-9_Lapatinib_30min_R1 1 ATSSSSGSLSATGR 14 0 Q03252 Q03252 LMNB2 Lamin-B2 1 ATSS(0.01)S(0.007)S(0.086)GS(0.887)LS(0.01)ATGR 171.36 0.00022715 21450000.0 17818.0 19062.0 27523.0 21286.0 17476.0 20856.0 17892.0 18378.0 24963.0 18379.0 True False 17563.912052578995 19017.86311016579 25260.165181852393 22851.443448014405 16448.09603913796 19964.03749771058 18818.360213771648 19231.90897218751 22151.40406795637 21555.785661521873 0.8148119640998024 0.8822625817862719 1.171850823648846 1.0601071938103996 0.7630478562652723 0.9261568012966169 0.8730073915776281 0.8921924384559735 1.0276314867751586 1.0 14.395787526121754 -1.5385231018016392 23.050396130137944 0.938939797756234 0.0017613642982700073 0.0 0.11695189250812259 0.0 0.0 0.028092028046936227 0.0 0.02893855877594551 1.5385231018016392 -0.937178433457964 ATSSSSGSLSATGR ddPTM_PC-9_Lapatinib_30min_R1 2 ATSSSSGSLSATGR 14 0 Q03252 Q03252 LMNB2 Lamin-B2 0 ; 144.7 3.6754e-06 1159200.0 3888.9 3882.0 1961.03 2640.6 4351.8 2090.46 1219.04 5740.8 4526.1 2903.08 False True 3833.4435728630824 3873.011467509369 1799.8016831947093 2834.798532783372 4095.8356799679877 2001.0558989002718 1282.1559263914703 6007.538525820769 4016.322956054052 3404.873509889052 1.12586959889385 1.1374905576552743 0.5285957548694242 0.832570879520204 1.2029332860889304 0.5877034471584457 0.37656492162413674 1.7643940394180826 1.179580664124267 1.0 11.733385488172441 -7.764535297442595 24.999987353078325 1.3539903910460829 0.8332492196323815 0.3303801423943399 0.31633579421033403 92.23201652711471 744759.5756099097 0.16668612559681759 0.08543857930399266 1.7197475624469436e-08 7.764535297442595 -0.5207411714137014 ATST(ph)ATSGFAGAIGQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATSTATSGFAGAIGQK 16 0 E7ER27;A0A2R8YD50;P51659-3;P51659;P51659-2;E7EPL9;A0A2R8Y7L2;E7ET17 E7ER27 HSD17B4 Peroxisomal multifunctional enzyme type 2;(3R)-hydroxyacyl-CoA dehydrogenase;Enoyl-CoA hydratase 2 1 AT(0.008)S(0.049)T(0.943)ATSGFAGAIGQK 99.34299999999999 0.0047101999999999995 8366000.0 51497.0 46517.0 54432.0 64746.0 67576.0 57715.0 56303.0 57529.0 52869.0 41312.0 True False 60214.42498788753 51134.900339856846 55729.86531450951 61118.491529364146 54334.96789837494 54688.32379854922 50969.57224157975 56018.92470701398 53642.109106678574 48801.538574387945 1.2338632499486255 1.0478132828109952 1.1419694325735397 1.2523886195965221 1.1133863702996252 1.1206270416082902 1.044425518754641 1.1478925940341944 1.0991888918606976 1.0 15.574639012145989 -6.699871818786603 2.7451603692203297 1.086985695600408 1.1595172759036418 0.2745899150438257 0.06461311975555113 0.4437756723580266 6.8168696397738815 0.02358618264723522 0.022691194138195644 1.9958512998668683e-07 6.699871818786603 0.07253158030323381 ATST(ph)SPNSQSSK ddPTM_PC-9_AZD4547_30min_R2 1 ATSTSPNSQSSK 12 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;H7C5N8;A0A2R8Y7F4;A0A2R8YET2;A0A2R8Y424 E7EPN9 PRRC2C Protein PRRC2C 1 ATS(0.004)T(0.598)S(0.393)PNS(0.002)QS(0.002)SK 148.62 0.00036954 5587900.0 33698.0 30548.0 23897.0 22246.0 18949.0 13770.0 11236.0 21231.0 28101.0 35310.0 True False 44413.26303805723 40422.04360130117 23580.11016597757 17117.528397273847 16318.258433548834 12908.959723197404 12235.982232983795 17950.23678984491 29586.361490671476 34073.80764752754 1.3034429112673571 1.1863083814829916 0.6920303832756005 0.5023661744629215 0.4789091551596206 0.37885286718562855 0.3591022864118229 0.5268045466338545 0.8683021808634974 1.0 15.056375552908728 -5.281121356288774 2.6511856319492857 0.5457855258455726 1.2950459640460825 0.6362679960865244 0.1951986299515586 0.16407512739654964 2.2332688183553424 0.05285436176118668 0.16285011368807709 5.2345414569015176e-06 5.281121356288774 0.7492604382005099 ATST(ph)SPNSQSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATSTSPNSQSSK 12 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;H7C5N8;A0A2R8Y7F4;A0A2R8YET2;A0A2R8Y424 E7EPN9 PRRC2C Protein PRRC2C 1 ATS(0.003)T(0.736)S(0.238)PNS(0.02)QS(0.002)SK 185.2 0.0010819 5975200.0 6320.8 11463.0 11416.0 9209.4 32019.0 36479.0 11323.0 25452.0 28238.0 44975.0 True False 7390.786598509414 12600.970883672184 11688.20073542109 8693.427175277642 25745.10680031472 34565.97702239065 10250.403468579076 24783.91196862314 28650.927328952515 53128.61147809586 0.13911123202526243 0.23717862246159732 0.2199982346657029 0.16362985844005754 0.4845808328894318 0.6506094561993531 0.1929356552599754 0.46648898360238866 0.539274912930199 1.0 15.697201387865004 -12.36510071584908 0.1307773559114576 2.2666865621024788 2.303071866942619e-14 0.742467468383565 0.13219919032678845 39.399309537030305 0.5690081247441429 15.31235018952816 1.2134627738882913 4.3141901621684786e-13 12.36510071584908 -2.2666865621024557 ATST(ph)SPNSQSSK ddPTM_PC-9_Lapatinib_30min_R1 1 ATSTSPNSQSSK 12 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;H7C5N8;A0A2R8Y7F4;A0A2R8YET2;A0A2R8Y424 E7EPN9 PRRC2C Protein PRRC2C 1 ATS(0.004)T(0.744)S(0.245)PNS(0.004)QS(0.002)SK 199.8 1.4898e-05 16573000.0 31532.0 27321.0 10907.0 28715.0 27023.0 11223.0 65007.0 54159.0 23678.0 21863.0 True False 31082.347897739404 27257.739903097237 10010.26856223754 30826.796890431924 25433.56026926213 10743.018452090806 68372.74437830616 56675.424857150014 21011.134299606256 25641.9904193837 1.21216595862399 1.063011858958193 0.39038578513274924 1.202199844327562 0.9918715299899648 0.41896195561986377 2.6664367024574176 2.2102584054593137 0.8194034065203919 1.0 14.646220632797865 -7.243352214976633 24.97904517469766 1.7748796211766886 0.8856027335491677 0.3145327866342845 0.5666074976242418 890.0845953264454 1229241.49950381 0.21555930491370454 0.16662965629444978 5.7101535255425774e-08 7.243352214976633 -0.8892768876275209 ATSTS(ph)PNSQSSK ddPTM_PC-9_AZD4547_30min_R2 3 ATSTSPNSQSSK 12 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;H7C5N8;A0A2R8Y7F4;A0A2R8YET2;A0A2R8Y424 E7EPN9 PRRC2C Protein PRRC2C 1 ATS(0.003)T(0.22)S(0.756)PNS(0.019)QS(0.002)SK;ATS(0.001)T(0.201)S(0.778)PNS(0.018)QS(0.001)SK;ATST(0.007)S(0.992)PNS(0.001)QSSK 201.09 3.6675e-06 21557900.0 83743.0 76483.0 55820.0 45422.0 37399.0 31955.9 26571.4 49708.0 63122.0 85918.0 True False 110371.53203739208 101204.63404341739 55079.790327859955 34950.65966290448 32206.79440373071 29957.69252131617 28936.203124377535 42026.7707762051 66458.50005388296 82910.03697140401 1.331220393442348 1.2206559994458 0.6643319957372252 0.4215491988618832 0.3884547104331766 0.3613276946390543 0.34900723942937983 0.506896056393031 0.8015736391096382 1.0 16.339259142456882 -5.28937446546016 2.884100952301824 0.5044745781421069 1.3195666683631464 0.6717257424934713 0.20018002334559748 0.14028886405623425 2.3025890401858478 0.05331720833702211 0.15371999834789013 5.13600614340286e-06 5.28937446546016 0.8150920902210395 ATSTS(ph)PNSQSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ATSTSPNSQSSK 12 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;H7C5N8;A0A2R8Y7F4;A0A2R8YET2;A0A2R8Y424 E7EPN9 PRRC2C Protein PRRC2C 1 ATS(0.025)T(0.029)S(0.843)PNS(0.097)QS(0.005)S(0.002)K;ATS(0.001)T(0.005)S(0.671)PNS(0.311)QS(0.012)SK;ATST(0.204)S(0.79)PNS(0.005)QSSK 193.51 1.7878e-05 22031400.0 18251.699999999997 25520.800000000003 30145.2 24099.4 75573.0 92912.0 33311.0 62895.0 69761.0 102562.0 True False 21341.352322493098 28054.336362908594 30863.975894307652 22749.188749308985 60765.013155319764 88039.5311577719 30155.540929244675 61244.07289276099 70781.12265015414 121155.67871965466 0.1761481801598043 0.2315560992219297 0.2547464239437313 0.187768241569171 0.5015449031978562 0.7266645037868089 0.24889911267817977 0.5054989872532122 0.5842163025138628 1.0 16.886502501749234 -9.754745602205583 0.15180924307548438 1.51509709095238 1.8376847067187216e-11 0.7251743928768297 0.13591318548067963 10.237338970707974 0.46897378332928163 3.5060225601161323 1.1000313777432367 1.758953659046975e-10 9.754745602205583 -1.5150970909340031 ATSTS(ph)PNSQSSK ddPTM_PC-9_Lapatinib_30min_R1 3 ATSTSPNSQSSK 12 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;H7C5N8;A0A2R8Y7F4;A0A2R8YET2;A0A2R8Y424 E7EPN9 PRRC2C Protein PRRC2C 1 ATS(0.004)T(0.023)S(0.965)PNS(0.008)QSSK;ATST(0.027)S(0.946)PNS(0.017)QS(0.007)S(0.002)K;ATS(0.002)T(0.161)S(0.72)PNS(0.056)QS(0.056)S(0.005)K 188.48 0.00011217 31239300.0 71994.0 62753.0 29896.5 60147.0 62197.0 23216.1 133266.0 104319.0 48228.0 50659.0 True False 70967.35235791736 62607.699284032795 27438.525173827336 64570.411024510126 58538.69474400682 22223.20152237239 140165.8614044541 109166.04157523258 42796.05477664541 59415.34065112556 1.1944280985380997 1.053729535132216 0.46180876644199703 1.0867632890241943 0.985245461904086 0.3740313743694979 2.359085378765708 1.837337636692731 0.720286281415685 1.0 15.858547853065451 -7.24385455676186 24.924349057928545 1.548955592893586 0.8661621538437053 0.2783839723467977 0.48363212698304264 966.4804522578727 1369870.3685413278 0.18493941532459277 0.14292641208497026 5.70355249667976e-08 7.24385455676186 -0.6827934390498808 ATSVALPGWS(ph)PSETR ddPTM_PC-9_AZD4547_30min_R2 4 ATSVALPGWSPSETR 15 0 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5;B1AL79 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 ATSVALPGWS(0.995)PS(0.004)ET(0.002)R;ATSVALPGWS(0.831)PS(0.12)ET(0.049)R;ATSVALPGWS(0.709)PS(0.291)ETR;ATSVALPGWS(0.998)PS(0.002)ETR 163.9 0.00032069 23394000.0 86369.0 77753.0 94528.0 133177.0 131930.0 116108.0 87436.0 132153.0 106308.0 99691.0 True False 113832.54541319847 102885.13670721374 93274.49695650191 102475.1002141392 113613.79677756602 108847.74840530162 95217.63461402373 111731.79042383199 111927.22384791647 96200.84843357858 1.1832800569507826 1.069482633287276 0.9695808142576087 1.0652203372706495 1.1810061826638685 1.1314634972315762 0.9897795722640252 1.161442879591407 1.163474394149404 1.0 16.553761997302757 -6.066680552516521 24.999761523642032 1.1095642057260293 1.0642747740289604 0.03456800081292344 0.0779039402742054 564.1777716398834 211518.7264322579 0.023521166730170694 0.030365710762309945 8.576684756173857e-07 6.066680552516521 -0.045289431697068894 ATSVALPGWS(ph)PSETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ATSVALPGWSPSETR 15 0 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5;B1AL79 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 ATSVALPGWS(0.816)PS(0.183)ET(0.001)R;ATSVALPGWS(0.856)PS(0.11)ET(0.034)R;ATSVALPGWS(0.495)PS(0.495)ET(0.01)R 144.41 6.7725e-06 15096200.0 89332.0 84957.0 100766.0 100699.0 118163.0 94119.0 97003.0 69498.0 82274.0 75471.0 True False 104454.14321257478 93390.96949874701 103168.64359718304 95057.16150056294 95009.80839019277 89183.23395296975 87814.17359909712 67673.75113921781 83477.10160288395 89153.2948718926 1.1716240365840487 1.0475324510770316 1.1572050561387501 1.0662215192063715 1.065690376634039 1.0003358157555495 0.9849795649760369 0.7590717901840928 0.9363322098508533 1.0 16.444000496608922 -7.017424052514387 1.3589565395850343 0.8904952694807292 1.1087133834902356 0.6086568668650636 0.06962783969838683 0.26515125160314973 0.9944214806389319 0.03612942597839971 0.02601754940847581 9.60673802055983e-08 7.017424052514387 0.21821811400950641 ATSVALPGWS(ph)PSETR ddPTM_PC-9_Lapatinib_30min_R1 4 ATSVALPGWSPSETR 15 0 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5;B1AL79 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 ATSVALPGWS(0.985)PS(0.015)ET(0.001)R;ATSVALPGWS(0.867)PS(0.13)ET(0.003)R;AT(0.001)S(0.007)VALPGWS(0.843)PS(0.118)ET(0.032)R;ATSVALPGWS(0.941)PS(0.058)ET(0.001)R 142.57 6.7725e-06 21324300.0 87943.0 89008.0 108280.0 79172.0 84698.0 87140.0 68301.0 64908.0 74917.0 53965.0 True False 86688.91669322902 88801.90744463519 99377.6363728871 84994.57299004955 79716.23016267494 83413.22533326145 71837.29158064029 67923.86263830372 66479.05854901599 63292.77834615743 1.3696494127515577 1.403033802039225 1.5701259917739163 1.342879475525657 1.2594838186229598 1.3178948295974995 1.1349998128973209 1.0731692368885786 1.0503419234566118 1.0 15.949753278278225 -7.145974725403353 0.7503908694697309 1.0028670768264036 1.4419909662772987 0.8628841633803516 0.06417411966930256 0.24366887343067006 0.27724799581036214 0.05445880710837781 0.03740971543019297 7.14537908763499e-08 7.145974725403353 0.4391238894508951 ATSVALPGWSPSET(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ATSVALPGWSPSETR 15 0 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5;B1AL79 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 ATSVALPGWS(0.222)PS(0.044)ET(0.734)R 144.4 2.4447e-07 0.0 17539.0 14932.0 15793.0 17521.0 22671.0 16142.0 14499.0 16477.0 13489.0 10931.0 True False 20508.006288959725 16414.350277849888 16169.56501528603 16539.355173848413 18228.780295135228 15295.485103633064 13125.549756330292 16044.49620882458 13686.251106319156 12912.703770251608 1.5882038846276514 1.271178412352756 1.2522214791713573 1.2808591808596983 1.4116935244135964 1.1845300082598447 1.0164834561270615 1.2425357612391001 1.0599059151228771 1.0 13.656503495417084 -1.522878745526649 0.1521257504098953 0.9512979596733787 2.8737894378974027 0.6416148845776932 0.10295066970052114 47.58858665733611 0.47467913923072097 0.36641074854877503 20.24647561123649 0.029999999982985408 1.522878745526649 1.9224914782240239 ATT(ph)PADGEEPAPEAEALAAAR ddPTM_PC-9_AZD4547_30min_R2 4 ATTPADGEEPAPEAEALAAAR 21 0 Q5JZ02;Q96S44 Q5JZ02 TP53RK TP53-regulating kinase 1 AT(0.005)T(0.995)PADGEEPAPEAEALAAAR;AT(0.194)T(0.806)PADGEEPAPEAEALAAAR;AT(0.005)T(0.995)PADGEEPAPEAEALAAAR;AT(0.001)T(0.999)PADGEEPAPEAEALAAAR 182.28 4.6253e-13 25269500.0 54539.1 56498.4 79411.8 119823.0 92105.0 86087.9 80431.2 103187.9 81785.79999999999 86867.1 True False 71881.3993162475 74760.4029135705 78358.74764525166 92199.65859689574 79317.81059802696 80704.81000396842 87589.42098411937 87242.58107704936 86108.83041897998 83825.90926928725 0.8575081373150572 0.8918531700432358 0.9347795726680093 1.0998945242658587 0.9462207006096622 0.9627668904217618 1.0448967598161327 1.0407591380462833 1.027234075593012 1.0 16.355108606732564 -5.5469481923999435 6.753658984230632 1.0154593823015956 0.8835640938531918 0.6607468898156845 0.0416617976391526 0.09892477882595432 16.81697382483106 0.01177855525583203 0.021057564408823108 2.8382575879903175e-06 5.5469481923999435 -0.1318952884484038 ATT(ph)PADGEEPAPEAEALAAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ATTPADGEEPAPEAEALAAAR 21 0 Q5JZ02;Q96S44 Q5JZ02 TP53RK TP53-regulating kinase 1 AT(0.003)T(0.997)PADGEEPAPEAEALAAAR;AT(0.162)T(0.838)PADGEEPAPEAEALAAAR;AT(0.178)T(0.822)PADGEEPAPEAEALAAAR;AT(0.004)T(0.996)PADGEEPAPEAEALAAAR 250.1 2.7469999999999994e-61 20788800.0 46226.4 48272.799999999996 46393.9 59730.2 71540.8 61641.4 57430.0 59789.799999999996 56120.6 50000.5 True False 54051.6165069826 53065.00456017889 47500.106525845564 56383.7105419212 57522.8937999298 58408.81647051704 51989.81464280633 58220.38110252959 56941.25760525577 59065.19484625975 0.9151178904543201 0.898414111699814 0.8041979146853431 0.9546012789542444 0.9738881578170632 0.9888872223743409 0.8802106685355078 0.9856969278450851 0.9640407985357137 1.0 15.850020628153883 -5.896650250857143 10.14677280405106 0.9618732568237529 0.8752722806053479 0.5112357039972131 0.04092138785122686 0.2738230928819668 24.834670069841536 0.011529038949555597 0.01711955387045311 1.2686731515175237e-06 5.896650250857143 -0.08660097621840501 ATT(ph)PADGEEPAPEAEALAAAR ddPTM_PC-9_Lapatinib_30min_R1 4 ATTPADGEEPAPEAEALAAAR 21 0 Q5JZ02;Q96S44 Q5JZ02 TP53RK TP53-regulating kinase 1 AT(0.006)T(0.994)PADGEEPAPEAEALAAAR;AT(0.006)T(0.994)PADGEEPAPEAEALAAAR;AT(0.026)T(0.974)PADGEEPAPEAEALAAAR;AT(0.005)T(0.995)PADGEEPAPEAEALAAAR 234.12 1.3177e-50 17553800.0 65500.0 47278.5 58929.299999999996 45527.3 56524.799999999996 52711.700000000004 52402.9 49804.2 55775.9 47908.600000000006 True False 64565.95798877109 47169.02953803241 54084.360427676285 48875.52951662061 53200.12239603256 50457.34346797426 55116.065752641065 52118.284951170994 49493.83079573477 56189.53767580319 1.1490743768225562 0.8394628517889502 0.9625343554119781 0.8698332739204544 0.9467976530253965 0.8979846703686729 0.9808955195653016 0.9275442921754917 0.8808371245426392 1.0 15.778013909490824 -4.748211309351658 24.999995096319402 0.9219768469732836 1.1490749243093146 0.6606795235867564 0.04862780548537651 373.90264206422637 706604.9297486071 0.011120125920629578 0.20916951212424545 1.785618556884622e-05 4.748211309351658 0.22709807733603093 ATT(ph)PASTANSDVATIPTDTPLKEENEGFVK ddPTM_PC-9_AZD4547_30min_R2 2 ATTPASTANSDVATIPTDTPLKEENEGFVK 30 1 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 AT(0.027)T(0.784)PAS(0.161)T(0.027)ANSDVATIPTDTPLKEENEGFVK;AT(0.233)T(0.672)PAS(0.022)T(0.009)ANS(0.031)DVAT(0.009)IPT(0.024)DT(0.001)PLKEENEGFVK 131.27 2.0455e-15 12830700.0 53260.0 54953.0 61397.0 99165.0 110665.0 104069.0 87582.0 100549.0 80048.0 100097.0 True False 70195.57212318033 72715.48258551455 60582.83566391288 76304.04133397734 95301.07496694708 97561.54897846276 95376.62833118449 85011.46243616033 84279.17385876914 96592.6344971555 0.7267176476612974 0.7528056664367707 0.6271993302522145 0.7899571404300436 0.9866287990079984 1.01003093544711 0.9874109845714291 0.8801029486224832 0.8725217434798409 1.0 16.55962556261094 -6.101984256113539 3.9992740277832057 0.9536118997202268 0.706901038755484 0.8214302182649562 0.05398126076399594 0.10195252665776604 2.874207627395886 0.017624039775054133 0.023617122109806564 7.907072919149894e-07 6.101984256113539 -0.2467108609647427 ATT(ph)PASTANSDVATIPTDTPLKEENEGFVK ddPTM_PC-9_Lapatinib_30min_R1 1 ATTPASTANSDVATIPTDTPLKEENEGFVK 30 1 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 AT(0.12)T(0.43)PAS(0.09)T(0.296)ANS(0.062)DVAT(0.001)IPTDTPLKEENEGFVK 68.835 7.128399999999999e-05 7265800.0 23231.0 19724.0 21635.0 17784.0 37020.0 34693.0 32430.0 33203.0 32887.0 34965.0 True False 22899.72167995637 19678.33028983895 19856.253813515097 19091.89468568488 34842.55638412036 33209.261263333006 34109.066718791335 34745.732593510846 29182.91974453716 41008.65366206607 0.558411935896816 0.47985799416872466 0.4841966765634781 0.46555770503983446 0.8496391193732487 0.8098110593192266 0.8317529026889998 0.8472780618411628 0.7116283305718963 1.0 15.323640759475378 -6.262638324900257 24.999999986939912 0.8319585318980364 0.4948662471238288 0.8531144743572544 0.06999376974295364 37.50120679928627 781961.1955082307 0.020089946628931425 0.02407726104496085 5.462125508251703e-07 6.262638324900257 -0.33709228477420755 ATT(ph)PPNQGRPDS(ph)PVYANLQELK ddPTM_PC-9_AZD4547_30min_R2 2 ATTPPNQGRPDSPVYANLQELK 22 1 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 2 AT(0.177)T(0.822)PPNQGRPDS(0.945)PVY(0.056)ANLQELK;AT(0.067)T(0.936)PPNQGRPDS(0.924)PVY(0.072)ANLQELK 70.02 0.0069605000000000005 50763000.0 113929.0 124445.0 156027.0 173619.0 168710.0 167946.0 122662.0 177700.0 135873.0 138934.0 True False 150156.05212958742 164669.4125953883 153957.98003376924 133593.82193681068 145287.52864657866 157444.31007059664 133578.68037221965 150240.54813976912 143054.9693897729 134069.96294821848 1.1199827972472987 1.228234937746557 1.1483405876171686 0.9964485631163208 1.0836694920449312 1.1743443990613018 0.9963356253317637 1.120613035432822 1.0670172963725264 1.0 17.03262652629816 -1.5228787452803376 0.15175670284614162 1.0062824858216333 1.6230453467028978 0.29377972473320124 0.06374264120638434 91.48101901590272 0.9108232945581634 0.22696996935238561 12.44893186072881 0.029999999999999995 1.5228787452803376 0.6167628608812645 ATT(ph)PPNQGRPDS(ph)PVYANLQELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ATTPPNQGRPDSPVYANLQELK 22 1 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 2 AT(0.126)T(0.874)PPNQGRPDS(0.874)PVY(0.126)ANLQELK;AT(0.175)T(0.825)PPNQGRPDS(0.967)PVY(0.033)ANLQELK;AT(0.479)T(0.522)PPNQGRPDS(0.997)PVY(0.002)ANLQELK 72.64399999999999 0.0053533 11439000.0 78992.1 83409.0 77221.8 89638.0 106515.0 92949.0 95462.0 86243.0 77673.2 79937.6 True False 92363.90236490882 91689.29428912282 79063.0605773074 84615.87347031702 85644.1503743253 88074.59081263712 86419.14827497072 83979.21263201188 78809.0236067423 94429.65409430656 0.9781239087529148 0.9709798809339388 0.8372694079589384 0.8960731062914987 0.906962449410148 0.9327005553221379 0.9151695948040244 0.8893309356840611 0.8345791834420573 1.0 16.526952365160177 -5.126970305547275 9.091932421175857 0.8991975869580334 0.9762572629419572 0.30149357054275705 0.0444102039895 0.3530117401768112 23.999029881993984 0.010892092780395032 0.029003754165584185 7.464997978454671e-06 5.126970305547275 0.07705967598392383 ATT(ph)PPNQGRPDS(ph)PVYANLQELK ddPTM_PC-9_Lapatinib_30min_R1 3 ATTPPNQGRPDSPVYANLQELK 22 1 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 2 AT(0.283)T(0.719)PPNQGRPDS(0.909)PVY(0.089)ANLQELK;AT(0.167)T(0.834)PPNQGRPDS(0.965)PVY(0.035)ANLQELK;AT(0.158)T(0.841)PPNQGRPDS(0.982)PVY(0.018)ANLQELK 73.072 0.0043887 53947900.0 175727.0 179763.0 199192.0 174474.0 173062.0 184051.0 161249.0 172026.0 180842.0 157979.0 True False 173221.10075561504 179346.7698181054 182815.20266335583 187305.39998820235 162882.83341298325 176179.5677738363 169597.6842225836 180018.95597178812 160473.6696093163 185285.45965621417 0.9348877190742123 0.9679484302269177 0.9866678313698131 1.0109017746764157 0.8790912881949959 0.9508547950860617 0.9153318589449044 0.9715762710457814 0.8660888442464151 1.0 17.49939014422643 -6.249909603569196 24.994000777050676 0.9293296032871232 0.9754166775627663 0.21857148900346557 0.041286550921409426 1104.169678562098 2393594.239506985 0.011603203083332535 0.014845129305066773 5.624583861744812e-07 6.249909603569196 0.04608707427564307 ATT(ph)PPNQGRPDSPVYANLQELK ddPTM_PC-9_AZD4547_30min_R2 1 ATTPPNQGRPDSPVYANLQELK 22 1 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 AT(0.068)T(0.932)PPNQGRPDSPVYANLQELK 83.24700000000001 0.00020718 9513400.0 29923.0 30604.0 28968.0 38299.0 41697.0 35041.0 31544.0 38307.0 27603.0 33483.0 True False 39437.8915629351 40496.14450616148 28583.865392645053 29469.757263651496 35908.091292611 32849.88073061439 34351.35489117488 32387.53335728836 29062.038227358622 32310.770361432023 1.2205803551502572 1.2533326829774378 0.8846544069640748 0.9120722574546931 1.1113350406362625 1.0166851598755406 1.06315493276442 1.0023757711437289 0.899453584741784 1.0 14.979727527657166 -5.247783510291065 24.789278538838072 0.991957737019887 1.2369565704447545 0.6805537146227264 0.06862486727486626 427.8901149661563 776738.1691989616 0.018541822529259705 0.04847237007228295 5.652186581736685e-06 5.247783510291065 0.2449988334248675 ATT(ph)PPNQGRPDSPVYANLQELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ATTPPNQGRPDSPVYANLQELK 22 1 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 AT(0.053)T(0.791)PPNQGRPDS(0.141)PVY(0.015)ANLQELK;AT(0.19)T(0.807)PPNQGRPDS(0.002)PVYANLQELK 72.30199999999999 0.00099449 17709800.0 29295.0 25948.3 32484.0 43976.0 37720.0 33122.6 35564.1 37936.7 34736.2 34277.8 True False 34254.06489737587 28524.27573765953 33258.541756256025 41512.16729211564 30329.036775285647 31385.592546995198 32195.210986213282 36940.90182225623 35244.151210565884 40492.09379708451 0.8459445211460568 0.7044406219298375 0.8213589033682098 1.0251919177146769 0.7490113237233827 0.775104214276393 0.7950986962430523 0.9122991270191128 0.870395870047686 1.0 15.30535262450431 -8.562087192601936 1.0372129011864566 0.9965996792861844 0.818156221330272 0.2948801865023516 0.08326974815113845 0.7982845736210681 1.8741268467215053 0.08289534606195205 0.027122417532307378 2.7410238057577396e-09 8.562087192601936 -0.17844345795591243 ATT(ph)PPNQGRPDSPVYANLQELK ddPTM_PC-9_Lapatinib_30min_R1 2 ATTPPNQGRPDSPVYANLQELK 22 1 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 AT(0.208)T(0.788)PPNQGRPDS(0.003)PVY(0.001)ANLQELK;AT(0.038)T(0.962)PPNQGRPDSPVYANLQELK 105.91 2.7009000000000002e-05 24064000.0 82126.0 68782.0 76733.0 71337.3 72191.0 69081.0 65235.0 66280.9 75592.0 61077.5 True False 80954.86817993602 68622.73950495358 70424.30893794556 76583.68301625676 67944.86731296677 66126.56666567626 68612.54910269364 69360.55258432178 67078.03294095083 71634.66449434705 1.1301074521864267 0.9579543645432842 0.9831037729436564 1.0690869226071444 0.9484914572096383 0.923108485709381 0.957812109360938 0.9682540299996139 0.9363906903792953 1.0 16.128370265809636 -6.2828150145598745 24.235862089671713 0.9525672373261332 1.0258439764653486 0.3919646408299876 0.04779760745294957 605.0767966254464 686038.5803671892 0.014572206603780212 0.016538140435835406 5.214167585253336e-07 6.2828150145598745 0.0732767391392154 ATT(ph)PSLPSVDNEFK ddPTM_PC-9_AZD4547_30min_R2 1 ATTPSLPSVDNEFK 14 0 A0A087WU78;A0A087WWC4;Q6T4R5-4;Q6T4R5-3;Q6T4R5-2;Q6T4R5 A0A087WU78 NHS Nance-Horan syndrome protein 1 AT(0.002)T(0.995)PS(0.003)LPSVDNEFK 170.95 0.00059827 13575000.0 54030.0 66384.0 69269.0 78962.0 98525.0 78803.0 74002.0 106580.0 88597.0 96860.0 True False 71210.41610618535 87841.32979012614 68350.44780043935 60758.530850738956 84846.50441529346 73875.43595258701 80588.03463913017 90110.5099647529 93280.05654563975 93468.96088188946 0.7618616429915086 0.9397914447890933 0.7312635890625689 0.6500396524950726 0.9077505903003283 0.7903739942710876 0.8621903344037807 0.9640688108068258 0.9979789618450083 1.0 16.51219973475075 -7.688470683651863 1.5492140773148775 1.0058537713111668 0.7951839418944847 0.5500647250758948 0.07743064384702131 0.32724441501588714 1.4938506583588527 0.06035832485527474 0.02503314377729184 2.0489403557015346e-08 7.688470683651863 -0.2106698294166821 ATT(ph)PSLPSVDNEFK ddPTM_PC-9_Lapatinib_30min_R1 2 ATTPSLPSVDNEFK 14 0 A0A087WU78;A0A087WWC4;Q6T4R5-4;Q6T4R5-3;Q6T4R5-2;Q6T4R5 A0A087WU78 NHS Nance-Horan syndrome protein 1 AT(0.031)T(0.966)PS(0.002)LPSVDNEFK;AT(0.032)T(0.968)PSLPSVDNEFK 121.45 0.00017619 25082000.0 66968.0 74580.0 48255.0 46279.0 63852.0 61376.0 59381.0 50045.0 62513.0 47688.0 True False 66013.024039573 74407.31459218147 44287.660169686686 49682.512042218295 60096.350897861994 58751.09155444402 62455.45762653557 52370.27339825463 55472.12764892667 55930.807259734196 1.1802623147028528 1.3303458011368434 0.7918294467666361 0.888285266677812 1.0744767301280607 1.0504245233152607 1.1166557517487972 0.9363403813403767 0.9917991598319422 1.0 15.771355532708819 -5.244867439452159 24.999636405320583 0.9862720098993581 1.2553040828679902 0.5706401710350706 0.09501557415586862 625.5688939171744 943699.9891587221 0.025688838846392902 0.06756429666166207 5.6902658943000645e-06 5.244867439452159 0.2690320729686321 ATTPAS(ph)TANSDVATIPTDTPLKEENEGFVK ddPTM_PC-9_Lapatinib_30min_R1 1 ATTPASTANSDVATIPTDTPLKEENEGFVK 30 1 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 AT(0.071)T(0.29)PAS(0.319)T(0.319)ANS(0.001)DVATIPTDTPLKEENEGFVK 89.71 2.8005000000000004e-09 5480800.0 22707.0 21156.0 25355.0 21197.0 43027.0 39402.0 42642.0 40566.0 37763.0 43598.0 True False 22383.194016046178 21107.014581820764 23270.40977313036 22755.89809111911 40496.23645433674 37716.86831054814 44849.79411109154 42450.844453463855 33509.73327798086 51133.85620931662 0.437737258156719 0.4127796365566314 0.45508810596785143 0.44502605080218793 0.7919652350991337 0.7376104817159498 0.8771056485061238 0.8301905547606497 0.6553335844808701 1.0 15.641991209100137 -6.2652083617551195 4.963055730916267 0.8081141668073851 0.4346057595057056 0.8275959513693423 0.08445301814921073 0.07237705423484825 5.5252967514225 0.025039084969394266 0.03038891402426854 5.429897584288705e-07 6.2652083617551195 -0.3735084073016795 ATTPPNQGRPDS(ph)PVYANLQELK ddPTM_PC-9_AZD4547_30min_R2 2 ATTPPNQGRPDSPVYANLQELK 22 1 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 ATTPPNQGRPDS(0.995)PVY(0.005)ANLQELK;AT(0.002)T(0.007)PPNQGRPDS(0.941)PVY(0.049)ANLQELK 89.48299999999999 9.8182e-05 62266000.0 85915.0 79911.0 114525.0 161853.0 133407.0 105448.0 102272.0 137031.0 110323.0 118758.0 True False 113234.18285698514 105740.6680052239 113006.32367069423 124540.29145392278 114885.74082244164 98854.31989046597 111374.0098728838 115856.00760912048 116154.4485511315 114600.3185671219 0.9880791281628366 0.9226908731784296 0.9860908336350386 1.08673599699445 1.0024905886727755 0.8626007425325486 0.9718472973323505 1.0109571165045508 1.0135613059670454 1.0 16.806251528955436 -7.761756101617409 24.971453592658392 1.009194415735352 0.9739313601431213 0.07627347277470209 0.05386991686334724 25.675139674222315 2023645.0131841544 0.02994508203162486 0.01582132355027907 1.7307880913476372e-08 7.761756101617409 -0.03526305559223075 ATTPPNQGRPDS(ph)PVYANLQELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ATTPPNQGRPDSPVYANLQELK 22 1 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 ATT(0.001)PPNQGRPDS(0.995)PVY(0.004)ANLQELK;AT(0.01)T(0.04)PPNQGRPDS(0.938)PVY(0.012)ANLQELK;AT(0.021)T(0.184)PPNQGRPDS(0.784)PVY(0.012)ANLQELK;AT(0.004)T(0.041)PPNQGRPDS(0.946)PVY(0.01)ANLQELK 94.057 8.6587e-05 65507900.0 121441.0 122279.0 113448.0 147507.0 174043.0 146101.0 144180.0 133376.0 122794.0 112662.0 True False 141998.56273091704 134418.05100624217 116153.03057393577 139242.66101414614 139940.5235281296 138439.20636388863 130522.22662719543 129875.02132355342 124589.62994657506 133086.72876809843 1.0669626043506362 1.010003418451013 0.8727619323811816 1.046255042129515 1.0514987093264108 1.0402179664744544 0.9807305945180184 0.9758675603925816 0.9361536728704977 1.0 17.022007189224986 -7.466376553434779 6.7050116964745765 0.9690659893983942 1.011152709966294 0.12783659028427174 0.052973064634488726 0.5680259997310995 55.49245704554392 0.024157688435877976 0.015986013477070245 3.4168305900231844e-08 7.466376553434779 0.04208672056789986 ATTPPNQGRPDS(ph)PVYANLQELK ddPTM_PC-9_Lapatinib_30min_R1 2 ATTPPNQGRPDSPVYANLQELK 22 1 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 ATTPPNQGRPDS(0.998)PVY(0.002)ANLQELK;ATT(0.003)PPNQGRPDS(0.975)PVY(0.021)ANLQELK 130.72 5.8159000000000005e-06 50948000.0 81766.0 64656.0 72767.0 64291.0 67555.0 69457.0 65646.0 65821.0 73454.0 62935.0 True False 80600.00184595185 64506.29300445284 66784.37814874307 69019.17460848892 63581.547718240065 66486.48602217516 69044.82867165514 68879.2839513741 65180.83701508896 73813.23089438368 1.0919451820403183 0.8739123355371375 0.904775164825153 0.9350515317131372 0.8613841576616025 0.9007394096772154 0.9353990854356252 0.9331563341256616 0.8830508599244699 1.0 16.171591819613617 -4.754208617010378 24.99930647148729 0.9110285077814904 1.0919454976893113 0.6640466394896801 0.03787677104116764 143.7791638996374 497053.0827865355 0.008879199071485874 0.08852539276572978 1.761129869635335e-05 4.754208617010378 0.1809169899078209 ATVPVAAATAAEGEGS(ph)PPAVAAVAGPPAAAEVGGGVGGSSR ddPTM_PC-9_AZD4547_30min_R2 1 ATVPVAAATAAEGEGSPPAVAAVAGPPAAAEVGGGVGGSSR 41 0 O75179-4;O75179-6;O75179-2;O75179;H0YLQ3;A0A1W2PQ15;O75179-5;O75179-3 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 ATVPVAAAT(0.007)AAEGEGS(0.993)PPAVAAVAGPPAAAEVGGGVGGSSR 124.7 5.3531e-32 13516000.0 5616.7 7657.9 14677.0 16846.0 11880.0 12004.0 10378.0 7414.3 10618.0 13009.0 True False 7402.693765382404 10133.166416603513 14482.373390218567 12962.414968105508 10230.667063726856 11253.38798237194 11301.621895150047 6268.590298664553 11179.24580292338 12553.558869631428 0.5896888557467487 0.8071947183931135 1.1536468296056805 1.032568939431443 0.8149614917946554 0.8964300959782203 0.9002723460747082 0.4993476641774492 0.8905240274108502 1.0 13.615808798364283 ATVPVAAATAAEGEGS(ph)PPAVAAVAGPPAAAEVGGGVGGSSR ddPTM_PC-9_Lapatinib_30min_R1 2 ATVPVAAATAAEGEGSPPAVAAVAGPPAAAEVGGGVGGSSR 41 0 O75179-4;O75179-6;O75179-2;O75179;H0YLQ3;A0A1W2PQ15;O75179-5;O75179-3 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 ATVPVAAAT(0.001)AAEGEGS(0.999)PPAVAAVAGPPAAAEVGGGVGGSSR;ATVPVAAAT(0.001)AAEGEGS(0.999)PPAVAAVAGPPAAAEVGGGVGGSSR 112.0 2.4578000000000005e-27 15889700.0 22020.3 11719.599999999999 21257.7 12371.5 19082.5 15785.4 13648.1 8023.299999999999 18160.3 11449.9 True False 21706.286483971548 11692.463986250077 19509.973963095 13281.341380114172 17960.104867638478 15110.29523956465 14354.731837333826 8396.091808496682 16114.895777563115 13428.99995896726 1.6163740077664608 0.8706876179891857 1.4528240392217104 0.9890044992699185 1.3374119385297605 1.1251988447192376 1.0689352804523917 0.625220927407194 1.20000713581076 1.0 13.71306425259795 -7.301934981186727 2.7938358744492535 0.9271234718461098 1.2251764734681034 0.22379301355952663 0.24148018953685407 0.3907144994352016 6.058524409851626 0.10345858141325168 0.06777190680037391 4.989591817213772e-08 7.301934981186727 0.29805300162199366 ATVS(ph)PGPHAGEAEPPSR ddPTM_PC-9_Lapatinib_30min_R1 1 ATVSPGPHAGEAEPPSR 17 0 O15055 O15055 PER2 Period circadian protein homolog 2 1 AT(0.122)VS(0.878)PGPHAGEAEPPSR 60.325 0.020340999999999998 3886200.0 19030.0 23115.0 23273.0 20501.0 24622.0 22311.0 15955.0 21289.0 22159.0 19068.0 True False 18758.6287103254 23061.478637681368 21359.583776377964 22008.711929331195 23173.782368714514 21356.810539481245 16781.07183158542 22278.164659315473 19663.22007538538 22363.878393487088 0.838791392989705 1.0311931692669836 0.9550930031258978 0.9841187446154542 1.0362148264704967 0.9549689979400386 0.7503650098755895 0.9961673135283826 0.8792401626147186 1.0 14.448882784807669 -7.018179591192006 24.89420239223341 0.8984870597370499 0.974891118317229 0.11059954090663582 0.08251524800599976 1314.3578487858997 1799811.2755653048 0.02973108114010199 0.023503434981500083 9.590039783461574e-08 7.018179591192006 0.07640405858017907 ATVT(ph)PS(ph)PVKGK ddPTM_PC-9_Lapatinib_30min_R1 1 ATVTPSPVKGK 11 1 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 2 AT(0.001)VT(0.999)PS(1)PVKGK 86.756 0.010347 0.0 108990.0 130170.0 143040.0 144100.0 167180.0 137100.0 133140.0 126190.0 143420.0 125690.0 True False 107435.78261368185 129868.59936262105 131279.8033503675 154697.59470350825 157346.80108852615 131236.5525957097 140033.33774097668 132053.24807924347 127266.52932044628 147415.3490286026 0.7287964470567877 0.8809706738029227 0.8905436524448729 1.0493995077370994 1.0673705426562914 0.8902502586094088 0.9499237268285163 0.8957903566311913 0.8633193908169841 1.0 17.169527221492466 -4.7415044291830135 1.6223199800159431 0.953760354300669 0.6345555057352016 0.5203463418707631 0.06547063600508583 0.9987959169906921 2.3725221679513973 0.019923129429357162 0.5228075916445728 1.8134081816048005e-05 4.7415044291830135 -0.3192048485654674 ATVT(ph)PSPVK ddPTM_PC-9_Lapatinib_30min_R1 1 ATVTPSPVK 9 0 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 ATVT(0.697)PS(0.303)PVK 122.96 0.003728 2634400000.0 365240.0 1084500.0 1286800.0 1197400.0 1322600.0 993180.0 1354100.0 1266100.0 1064100.0 1108100.0 True False 360031.610623188 1081988.9068814795 1181004.271191643 1285460.7904093033 1244807.2683316462 950704.00661566 1424208.6723378147 1324927.6281252895 944249.8525302404 1299633.6085495641 0.2770254695282894 0.832533800113877 0.9087209375184476 0.9890947586711933 0.9578140024563492 0.7315169447462031 1.0958539875921496 1.0194624234163614 0.7265508111813573 1.0 20.309673526707506 -4.7314649075230015 2.88240338710601 0.9303285973271999 0.11147965132386706 0.749534742906871 0.11233350993627209 0.24673988619920298 2.549336919907073 0.02842323719535315 0.5067753123960854 1.8558167597059556e-05 4.7314649075230015 -0.8188489460033328 down ATVT(ph)PSPVKGK ddPTM_PC-9_Lapatinib_30min_R1 1 ATVTPSPVKGK 11 1 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 AT(0.177)VT(0.603)PS(0.221)PVKGK 130.69 0.002026 14407000.0 37114.0 44486.0 50619.0 50981.0 46387.0 45870.0 38585.0 40440.0 46843.0 36455.0 True False 36584.74755412596 44382.99540021171 46457.301214990584 54730.31280763051 43658.6078603509 43908.24702819255 40582.742502145025 42318.99003347822 41567.04806134197 42756.19817676589 0.8556595093622344 1.0380482197392806 1.0865629591977126 1.2800556443620252 1.021105938368379 1.0269446045381252 0.9491663017924279 0.9897743915050602 0.9721876554480442 1.0 15.383845955821776 -6.85677566605746 2.7494459369818984 0.9786856308171175 1.0705849739059816 0.11899845681661725 0.09755364246499473 0.5677227425964294 8.699983905915511 0.04003398215337478 0.035136947501327113 1.39067079392069e-07 6.85677566605746 0.09189934308886416 ATVTPS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 7 ATVTPSPVK 9 0 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 AT(0.051)VT(0.146)PS(0.802)PVK;AT(0.028)VT(0.152)PS(0.819)PVK;AT(0.001)VT(0.147)PS(0.852)PVK;ATVT(0.039)PS(0.961)PVK;AT(0.005)VT(0.122)PS(0.873)PVK;ATVT(0.02)PS(0.98)PVK;ATVT(0.016)PS(0.984)PVK 110.93 0.0022688 5932291000.0 3220722.0 3657498.0 3747428.0 3085362.0 3307700.0 3841248.0 4021248.0 4245548.0 3935968.0 3469716.0 True False 4244844.600820751 4839712.702228357 3697734.6561940447 2374079.459267715 2848482.950058018 3601054.155324081 4379131.28181039 3589496.109587509 4144015.2330420734 3348242.298939354 1.2677829803910607 1.445448766883289 1.1043808440522367 0.7090524661311903 0.850739789937052 1.075505842711805 1.3078896002232567 1.072053868599826 1.2376688611677842 1.0 21.67497250307553 -5.376021744936684 5.48634356938221 1.0352137737033047 1.3532954557956558 0.3638831291771545 0.1664476215782792 0.25035522559607504 10.260134090624494 0.04891162089073177 0.10439402122201068 4.2070556331167595e-06 5.376021744936684 0.3180816820923511 ATVTPS(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 9 ATVTPSPVK 9 0 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 ATVT(0.213)PS(0.786)PVK;AT(0.003)VT(0.171)PS(0.826)PVK;ATVT(0.022)PS(0.978)PVK;AT(0.168)VT(0.237)PS(0.595)PVK;AT(0.014)VT(0.133)PS(0.852)PVK;AT(0.006)VT(0.194)PS(0.8)PVK;AT(0.005)VT(0.139)PS(0.856)PVK;ATVT(0.088)PS(0.912)PVK;ATVT(0.04)PS(0.96)PVK 124.39 0.0014604000000000002 6350313000.0 3833331.0 6800480.0 5496156.0 4533735.0 5020338.0 2828910.0 4589576.0 3828548.0 3060406.0 2787025.0 True False 4482238.226561628 7475586.711593375 5627205.2033277005 4279724.526517192 4036638.807697873 2680556.9795885608 4154818.135627232 3728052.6716819103 3105158.64803067 3292290.570422245 1.3614345789614704 2.2706339406228686 1.7092067309860794 1.2999230884922486 1.2260882572039087 0.8141921018972429 1.261984034141423 1.1323583359180163 0.943160569096556 1.0 21.650660239836938 -5.865957986449949 2.2455098695730813 1.0688834567754106 1.8532280494601834 0.6442454724729412 0.23870543218253018 0.17447055323722027 1.7914306082800309 0.07032541868396111 0.12138201222690105 1.361576394687717e-06 5.865957986449949 0.7843445926847727 ATVTPS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 4 ATVTPSPVK 9 0 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 AT(0.001)VT(0.211)PS(0.789)PVK;ATVT(0.018)PS(0.982)PVK;AT(0.002)VT(0.018)PS(0.979)PVK;AT(0.001)VT(0.005)PS(0.994)PVK 115.0 0.0020050000000000003 3476450000.0 756176.0 2018960.0 2023050.0 2086840.0 2449550.0 1917500.0 2321100.0 2578800.0 1967780.0 1958610.0 True False 745392.7915743057 2014285.222164532 1856722.6381988323 2240313.1750941607 2305472.285000591 1835492.9949108197 2441275.2007704736 2698620.4623722457 1746147.8947579686 2297153.128816218 0.3244854608183764 0.8768615365239255 0.808271166126243 0.9752563496925656 1.003621507021023 0.7990294473127685 1.062739427400961 1.1747673363694802 0.7601356099659771 1.0 21.131415599666646 -4.647966787787419 2.0000659095564832 0.9578348027041061 1.0178874139936723e-26 0.6949091812154451 0.12272752032763991 0.667404053894016 2.1477658404499973 0.032660598288326716 1.3302176846597007 2.2492266064920486e-05 4.647966787787419 -0.9578348027041061 ATVTPS(ph)PVKGK ddPTM_PC-9_AZD4547_30min_R2 5 ATVTPSPVKGK 11 1 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 ATVT(0.082)PS(0.918)PVKGK;ATVT(0.005)PS(0.995)PVKGK;AT(0.003)VT(0.434)PS(0.563)PVKGK;AT(0.001)VT(0.004)PS(0.996)PVKGK;AT(0.063)VT(0.103)PS(0.834)PVKGK 144.51 2.7054000000000002e-05 3689913600.0 474752.0 404232.0 559385.0 712442.0 777273.0 623443.0 531393.0 608206.0 542942.0 666005.0 True False 625713.2605449506 534892.0888123991 551967.1894043337 548199.5040191752 669362.0606585988 584459.0106542748 578685.9475553554 514221.7378834907 571640.8056819389 642688.3676661435 0.9735873434541281 0.8322728646152482 0.8588411074075382 0.8529787243697986 1.041503307566182 0.9093972134219225 0.9004145347406765 0.8001105415223771 0.8894525472085227 1.0 19.293759834998305 -10.238286671031728 4.047362344327989 1.0000006503257015 0.8932703786038755 0.18241000150696884 0.06630064091725152 22534462.502700143 53371548.01662369 248.15013576090234 0.0169190424633454 5.777145811113768e-11 10.238286671031728 -0.10673027172182603 ATVTPS(ph)PVKGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ATVTPSPVKGK 11 1 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 AT(0.002)VT(0.057)PS(0.942)PVKGK;AT(0.001)VT(0.142)PS(0.857)PVKGK;AT(0.019)VT(0.347)PS(0.635)PVKGK;AT(0.001)VT(0.078)PS(0.921)PVKGK 126.83 0.0018864 937840000.0 217681.0 180539.0 219181.0 284977.0 288516.0 228031.0 237083.0 294698.0 216879.0 174396.0 True False 254530.09390427294 198461.7187793156 224407.10628857126 269010.6625979001 231983.36092943556 216072.65293436707 214624.781907722 286962.48975834105 220050.44508024296 206012.61428202363 1.2355073245943604 0.9633474118610468 1.0892881830108045 1.3057970432317045 1.1260638662245164 1.0488321488827457 1.0418040791128869 1.3929364993422202 1.06814063715051 1.0 17.652373151675178 -5.558379952596375 24.99819206334654 1.1521324683569905 1.0811492297666432 0.014840679703765458 0.13153891811833587 551.5169287655464 388348.584049214 0.0352283655864329 0.06101756311684315 2.7645219809670885e-06 5.558379952596375 -0.07098323859034728 ATVTPS(ph)PVKGK ddPTM_PC-9_Lapatinib_30min_R1 2 ATVTPSPVKGK 11 1 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 ATVT(0.017)PS(0.983)PVKGK;ATVT(0.028)PS(0.972)PVKGK 150.14 0.0010328 1397620000.0 215042.0 276368.0 294533.0 283066.0 284114.0 234900.0 225630.0 220292.0 268774.0 204767.0 True False 211975.4616461266 275728.0868759989 270317.63367025816 303883.6179204946 267402.9731096157 224853.87457864458 237312.01738393123 230527.5705354844 238501.8418043066 240160.70311512373 0.8826400776504797 1.148098266283912 1.1255697962404714 1.2653344780341709 1.1134335036545635 0.9362642250046143 0.9881384185912091 0.9598888058925212 0.993092702972218 1.0 17.87364058027228 -6.750273885174967 23.830246263254264 0.9737612371754749 1.1191240099593696 0.3439412469000639 0.09004606961181472 134.50399990556988 287067.40444846783 0.030504014182029367 0.030203300250865286 1.7771583024860035e-07 6.750273885174967 0.14536277278389464 ATVVESSEK ddPTM_PC-9_Lapatinib_30min_R1 1 ATVVESSEK 9 0 P61981 P61981 YWHAG 14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed 0 99.01299999999999 0.019708 8405900.0 40199.0 42243.0 45535.0 45517.0 41062.0 30635.0 39738.0 35997.0 39550.0 38636.0 False True 39625.754888406256 42145.18892890219 41791.28807018304 48864.47202026085 38646.81389099808 29324.812463672977 41795.439200472676 37669.552033509295 35095.46252003663 45314.18112076603 0.8744669749807539 0.9300662151784623 0.9222562790841529 1.0783483406669758 0.8528635613650644 0.6471442656222769 0.92234788683667 0.8312972032555732 0.7744918180581114 1.0 15.467674993417681 -6.503286142583107 24.750325006712075 0.8210831410055491 0.9499342519844982 0.2345198063801922 0.09906659332638064 894.5626233077664 1130056.497256972 0.030241809268337277 0.03379242717680445 3.1384401958128475e-07 6.503286142583107 0.12885111097894908 ATVVGGQAEAPDS(ph)VAMSSWER ddPTM_PC-9_AZD4547_30min_R2 1 ATVVGGQAEAPDSVAMSSWER 21 0 C9IZ84 C9IZ84 OTOG 1 ATVVGGQAEAPDS(0.932)VAMS(0.038)S(0.03)WER 50.891000000000005 0.022415 94538000.0 15423.0 17806.0 40044.0 111360.0 55614.0 39827.0 32197.0 37264.0 26218.0 34986.0 True False 20327.19318167124 23561.4412846919 39512.990395715184 85687.67249484929 47892.95606751727 37336.61139402927 35062.47062614627 31505.70504153271 27603.82995489216 33761.15078890962 0.6020882791811891 0.6978862015696374 1.170368588522611 2.5380554422036257 1.418581859574819 1.1059045832730967 1.0385448898164968 0.9331940501234984 0.817621121018182 1.0 15.043076460406073 -7.117801468525611 2.6996555496528067 0.9345120371567862 1.3106870972936364 0.09133414626635294 0.4948636679626648 0.7857005604543312 11.111859619153208 0.23924136894002926 0.17802476727482724 7.624274631202242e-08 7.117801468525611 0.3761750601368502 AVAAPRPDR ddPTM_PC-9_AZD4547_30min_R2 3 AVAAPRPDR 9 1 O75534;O75534-2;O75534-4;O75534-3;E9PLT0 O75534 CSDE1 Cold shock domain-containing protein E1 0 ;; 85.86200000000001 0.015694999999999997 5684300.0 15047.499999999998 14387.3 18663.4 27464.1 21882.5 20780.3 17954.699999999997 21556.9 15838.7 24717.699999999997 False True 19832.29199255642 19037.71336601414 18415.91112155108 21132.676061115184 18844.492594444695 19480.904555988298 19552.633517137256 18225.776433281888 16675.901346653085 23852.340846482344 0.8314610343781506 0.798148638263391 0.7720798239501507 0.8859791245282223 0.7900479334808689 0.8167292544312803 0.8197364628897967 0.7641085019950886 0.6991305991299545 1.0 14.541843237473824 AVAGVMITAS(ph)HNR ddPTM_PC-9_AZD4547_30min_R2 3 AVAGVMITASHNR 13 0 Q6PCE3 Q6PCE3 PGM2L1 Glucose 1,6-bisphosphate synthase 1 AVAGVMIT(0.004)AS(0.996)HNR;AVAGVMIT(0.043)AS(0.957)HNR;AVAGVMIT(0.012)AS(0.988)HNR 118.2 0.00017123 55277200.0 101684.0 100463.0 138670.0 204239.0 148344.0 120509.0 129721.0 145886.0 137090.0 131950.0 True False 134017.39684140924 132935.70008895878 136831.14519463162 157154.8540110948 127748.99620382977 112973.55317957864 141265.9176971248 123342.67082677763 144336.2975252182 127330.47066245435 1.0525163077161754 1.0440211160560584 1.0746143046730976 1.2342281717288486 1.0032869236970379 0.8872468042552434 1.1094431439872119 0.9686814961499032 1.1335566166863964 1.0 16.95821817736276 AVAGVMITAS(ph)HNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AVAGVMITASHNR 13 0 Q6PCE3 Q6PCE3 PGM2L1 Glucose 1,6-bisphosphate synthase 1 AVAGVMIT(0.019)AS(0.981)HNR;AVAGVMIT(0.022)AS(0.978)HNR;AVAGVMIT(0.005)AS(0.995)HNR;AVAGVMIT(0.013)AS(0.987)HNR 132.23 4.0689e-05 48284400.0 194036.0 169696.0 165550.0 209970.0 212389.0 185359.0 200444.0 179277.0 152574.0 159107.0 True False 226882.46241431058 186542.29739820576 169497.33985187157 198206.06163192447 170772.90009719392 175638.44773412953 181456.4932311102 174571.1687096828 154805.10610835024 187951.8396096813 1.2071308420576052 0.9925005138848189 0.9018126143583691 1.054557710334403 0.9085992478277265 0.9344864519489517 0.9654414322729696 0.9288079811946183 0.8236424098313337 1.0 17.520003510502903 -4.772920406142508 3.2166881167133754 0.940807645628818 1.2484781032863579 0.6554809489880574 0.05798039795007815 0.20902843061177756 3.264719015574643 0.014467523788753099 0.16526012490573347 1.6868621510364873e-05 4.772920406142508 0.30767045765753986 AVAGVMITAS(ph)HNR ddPTM_PC-9_Lapatinib_30min_R1 5 AVAGVMITASHNR 13 0 Q6PCE3 Q6PCE3 PGM2L1 Glucose 1,6-bisphosphate synthase 1 AVAGVMIT(0.059)AS(0.941)HNR;AVAGVMIT(0.007)AS(0.993)HNR;AVAGVMIT(0.061)AS(0.939)HNR;AVAGVMIT(0.035)AS(0.965)HNR;AVAGVMIT(0.388)AS(0.612)HNR 117.13 0.00018263 59398800.0 209286.0 202550.0 204182.0 179355.0 186997.0 195055.0 181103.0 162911.0 181115.0 133067.0 True False 206301.54326164807 202081.00791963513 187394.9441253127 192545.3650107406 175998.2041102471 186712.95234541327 190479.6271962156 170480.4397958448 160715.921474499 156067.45364936796 1.3218742180873888 1.294831197628459 1.2007304517591941 1.2337317006742896 1.1277060014425362 1.1963605990836221 1.2204955148698742 1.0923510047063245 1.029784991786786 1.0 17.25181018308983 -1.5228787452803376 0.1019943260610519 0.8784375109769799 2.1835447158873493 0.8177332442825934 0.043380049215510516 54.34773072107631 0.39319526955415784 0.5581044819400789 9.931818217063634 0.029999999999999995 1.5228787452803376 1.3051072049103696 AVAHHTDCTFIR ddPTM_PC-9_AZD4547_30min_R2 2 AVAHHTDCTFIR 12 0 P62195-2;P62195;J3QQM1;J3QRW1;J3QLH6;J3KRP2;J3QSA9;J3QRR3 P62195-2 PSMC5 26S protease regulatory subunit 8 0 ; 98.75399999999999 0.0014972999999999998 7397900.0 9070.4 9414.4 29004.0 48487.0 37245.0 29765.0 21869.0 36981.0 20810.9 32743.0 False True 11954.59852395972 12457.420691373887 28619.388009123042 37309.071266682404 32074.174645497216 27903.789844660176 23815.29863413338 31266.43618883964 21910.921687705613 31596.677536193543 0.37834986005303556 0.39426362715206653 0.9057720697481544 1.1807909620859787 1.0151122569376703 0.883124176986545 0.7537279388585492 0.9895482255380929 0.6934565086030633 1.0 14.94748524320304 -5.265682798790214 5.913580343886642 0.9329142866844881 0.38139539423386826 0.736475895386276 0.12960691519132775 0.07325343686274127 11.418171462124358 0.03556550151431634 0.08433718962431631 5.423969031199932e-06 5.265682798790214 -0.5515188924506198 down AVAHHTDCTFIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AVAHHTDCTFIR 12 0 P62195-2;P62195;J3QQM1;J3QRW1;J3QLH6;J3KRP2;J3QSA9;J3QRR3 P62195-2 PSMC5 26S protease regulatory subunit 8 0 ; 82.48899999999999 0.0050717 3880600.0 31572.0 37525.0 34821.0 40724.0 57460.0 37453.0 32743.0 37247.0 32637.0 21991.6 False True 36916.51602457592 41250.23400591458 35651.264699377876 38442.36630898937 46201.12548006131 35488.89874776167 29641.346001208556 36269.305716458686 33114.254381862134 25978.50299459019 1.4210409288119288 1.5878603172209191 1.3723371476332549 1.4797760408671228 1.7784367902062068 1.366087135781147 1.1409951530841143 1.3961276261380984 1.274679083269652 1.0 14.665030677752238 -8.286792011963305 0.5046998417170849 1.0048253888854162 1.522622241618872 0.5347218179923183 0.1409014274884695 0.7714712939477701 0.5011859678243095 0.16580572027445015 0.08863696618886702 5.166637455451714e-09 8.286792011963305 0.5177968527334558 AVAHHTDCTFIR ddPTM_PC-9_Lapatinib_30min_R1 2 AVAHHTDCTFIR 12 0 P62195-2;P62195;J3QQM1;J3QRW1;J3QLH6;J3KRP2;J3QSA9;J3QRR3 P62195-2 PSMC5 26S protease regulatory subunit 8 0 ; 68.069 0.014887000000000001 5325100.0 12952.1 10652.7 21348.6 14661.4 16117.6 22312.0 16320.3 15580.1 25070.0 12404.0 False True 12767.400678875752 10628.034327649942 19593.40051597913 15739.648264996638 15169.594456420808 21357.76777181235 17165.285278158808 16304.008323951393 22246.3526011964 14548.014872708916 0.8776043185676504 0.730548767006515 1.3468092167499095 1.0819103776504342 1.0427260756295988 1.468088117773241 1.179905672928594 1.1207033032758718 1.5291675734349872 1.0 13.828534685350615 -5.257100965299964 24.978940172161213 1.2214737368617292 0.804076509019893 0.48599681949258144 0.17157438774739148 287.04901148536067 1652703.8596548475 0.04263170823270237 0.10488976251262505 5.532214806737485e-06 5.257100965299964 -0.4173972278418362 AVAQALEVIPR ddPTM_PC-9_Lapatinib_30min_R1 2 AVAQALEVIPR 11 0 P49368-2;P49368;B4DUR8 P49368-2 CCT3 T-complex protein 1 subunit gamma 0 ; 115.7 0.006144600000000001 7334100.0 32204.0 50491.0 40907.0 45835.0 36423.0 39973.0 48754.0 41864.0 38451.0 43625.0 False True 31744.765054509688 50374.09119165777 37543.78436558642 49205.85880107775 34280.670750373196 38263.447971614136 51278.243564845914 43809.15427204584 34120.243473019655 51165.52312334143 0.6204327272875648 0.9845319292490021 0.7337711426321595 0.9616995155597327 0.669995509822796 0.7478365437479239 1.0022030546083298 0.8562241055649511 0.6668600532191996 1.0 15.642884385609733 AVAS(ph)PEATVSQTDENK ddPTM_PC-9_AZD4547_30min_R2 4 AVASPEATVSQTDENK 16 0 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 AVAS(1)PEATVSQTDENK;AVAS(0.995)PEAT(0.003)VS(0.001)QTDENK;AVAS(0.95)PEAT(0.048)VS(0.002)QTDENK;AVAS(1)PEATVSQTDENK 239.19 2.6495999999999996e-37 51805000.0 167173.0 162289.0 210641.0 216192.0 204802.0 218470.0 191933.0 231500.0 205443.0 201575.0 True False 220330.53658558786 214745.745515633 207847.76270961532 166352.27453310377 176368.77743984727 204809.03636361237 209014.66517651093 195726.99434078025 216302.29755980294 194517.9206046552 1.1327004519722124 1.1039895185394744 1.068527578659717 0.8552028214984045 0.9066968066058301 1.0529057463033094 1.074526524480587 1.0062157447106501 1.1119916195249848 1.0 17.5695435488076 -5.5316019121625475 24.98586999071062 0.9994881918659553 1.1103234145781327 0.30817107832608126 0.07152348492347001 244.05189053203335 699038.503220878 0.021401292575127306 0.03714263866288313 2.9403436275551306e-06 5.5316019121625475 0.11083522271217738 AVAS(ph)PEATVSQTDENK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AVASPEATVSQTDENK 16 0 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 AVAS(0.996)PEAT(0.003)VSQTDENK;AVAS(1)PEATVSQTDENK;AVAS(1)PEATVSQTDENK 262.73 8.206799999999997e-69 29222500.0 86788.0 98581.0 90190.0 83696.0 103640.0 62544.0 105319.0 76062.0 70080.0 69804.0 True False 101479.49425886538 108367.47018086763 92340.47164747976 79006.78446609309 83332.48598596502 59264.08253758057 95342.42187647098 74065.45309435064 71104.7874216656 82458.91263184004 1.2306673835483113 1.3141996022273943 1.1198361547618096 0.9581351723474707 1.0105940440668346 0.7187104540437125 1.1562415612021568 0.8982104023737949 0.8623056641449061 1.0 16.331387816387902 -5.580499540690241 2.3505143109560542 0.9381575933375846 1.2745697416164379 0.6020734767325732 0.1081215818015578 0.19286000977489534 2.130883965577339 0.030466114115879923 0.0677105674119937 2.627244305040454e-06 5.580499540690241 0.33641214827885324 AVAS(ph)PEATVSQTDENK ddPTM_PC-9_Lapatinib_30min_R1 4 AVASPEATVSQTDENK 16 0 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 AVAS(1)PEATVSQTDENK;AVAS(0.994)PEAT(0.005)VSQTDENK;AVAS(1)PEATVSQTDENK;AVAS(1)PEATVSQTDENK 285.79 1.5848999999999997e-96 50842800.0 136237.0 204139.0 209361.0 196649.0 230585.0 222729.0 235631.0 219801.0 222616.0 199198.0 True False 134294.23539719387 203666.3286877631 192148.14673683108 211111.22346183308 217022.44364755234 213203.39987665776 247830.82022866243 230013.75688300072 197542.64182959462 233629.10888534904 0.5748180782690796 0.8717506549567424 0.8224495126209881 0.9036169528234328 0.9289186809082671 0.9125720715789959 1.060787422470899 0.9845252502156205 0.8455395082063021 1.0 17.833860511618113 -4.166017139066666 0.7639788303414741 0.9567206175277737 1.4199135147543197e-23 0.7327923740269062 0.0651039660578633 3.3046519279177704 0.7536873674354619 0.024881673362414394 3.3637115793051424 6.823117667500076e-05 4.166017139066666 -0.9567206175277737 AVAS(ph)PEATVSQTDENKAR ddPTM_PC-9_AZD4547_30min_R2 2 AVASPEATVSQTDENKAR 18 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 AVAS(0.603)PEAT(0.396)VS(0.001)QTDENKAR;AVAS(0.994)PEAT(0.006)VSQTDENKAR 114.1 6.8365e-05 26760000.0 26040.0 16252.8 35288.0 69221.0 55660.0 32533.0 18604.9 41787.0 23286.4 36114.0 True False 34320.178334352524 21506.199759173356 34820.058063230405 53263.16790378918 47932.56976153511 30498.706367086477 20260.70005753297 35329.779319732894 24517.271563872193 34849.659852246084 0.984806694810267 0.6171136203439089 0.9991505859987965 1.528369807040063 1.3754099742940769 0.8751507617690798 0.5813743991600869 1.0137768767190956 0.703515376271084 1.0 15.08885695438425 -6.978181901145196 24.835266961687807 0.8118786515742593 1.0954874274092485 0.21351315357672318 0.2563481309834011 381.95683791203174 434775.1478213174 0.1006188522370992 0.08873073574908535 1.0515213593573867e-07 6.978181901145196 0.2836087758349892 AVAS(ph)PEATVSQTDENKAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVASPEATVSQTDENKAR 18 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 AVAS(0.948)PEAT(0.051)VSQTDENKAR 60.542 0.012214000000000001 11080000.0 14711.0 7886.8 13148.0 24644.0 23902.0 29849.0 21812.0 24736.0 26169.0 16359.0 True False 17201.281744505766 8669.749381954625 13461.498184067677 23263.27657692599 19218.57468194267 28283.66589383864 19745.80945479525 24086.70620995844 26551.672118115945 19324.757202227243 0.8901163189011896 0.44863432390009056 0.6965933927757806 1.2038069267046119 0.9945053632926196 1.4635974774668243 1.0217882298940075 1.246417016156993 1.3739718352091779 1.0 14.238162667679227 -5.74198454933768 5.711813173474533 1.1945158224952024 0.6489150617993403 0.6319691641057423 0.17730057970274923 0.09717996926255337 9.738688348055287 0.046810623276357724 0.07850564918993638 1.8114045348428379e-06 5.74198454933768 -0.545600760695862 AVAS(ph)PEATVSQTDENKAR ddPTM_PC-9_Lapatinib_30min_R1 2 AVASPEATVSQTDENKAR 18 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 AVAS(0.982)PEAT(0.018)VSQTDENKAR;AVAS(0.968)PEAT(0.032)VSQTDENKAR 103.71 0.00018192 27054000.0 103467.0 32437.0 54418.0 34637.0 30383.0 35854.0 24705.0 19880.6 49271.0 26029.0 True False 101991.54160647608 32361.89411942335 49943.96209955466 37184.32052564479 28595.931675276293 34320.60799975617 25984.10401750661 20804.325253698506 43721.581133368505 30528.07796853762 3.340909365849663 1.060069820077624 1.6360008694627661 1.218036738636711 0.936709206021663 1.1242308813259436 0.851154273265613 0.6814816601012204 1.4321760177115694 1.0 14.897849140645151 -3.212576694599939 1.4781951465399454 1.0616547169780142 199.99999999351866 0.8411819429450098 0.28707212001730925 45.912972246956 1.479227910500365 0.08072800811852213 29892.770924967543 0.0006129475386045305 3.212576694599939 198.93834527654064 up AVAS(ph)SPAATNSEVK ddPTM_PC-9_AZD4547_30min_R2 1 AVASSPAATNSEVK 14 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 AVAS(0.497)S(0.497)PAAT(0.005)NS(0.001)EVK 198.81 7.178499999999999e-08 11732000.0 58955.0 49646.0 55716.0 86919.0 75947.0 71679.0 57596.0 73354.0 53688.0 65526.0 True False 77701.46365982153 65693.098619556 54977.16943581229 66881.16743516349 65403.06999064512 67196.90079877009 62721.932421763515 62018.82480722929 56525.838073775645 63231.954684562115 1.2288322264817175 1.038922471197854 0.8694523158436346 1.057711528432195 1.0343357297257976 1.0627047848510685 0.9919341057010986 0.9808146073708361 0.8939441830599656 1.0 15.94836619767177 -4.795166008020859 4.016568305690153 0.9908138507526836 1.2464252836000826 0.5919076716753577 0.060105974990391865 0.15690647396076715 4.7104343437112375 0.01554495861446426 0.11265724639335879 1.602632671109377e-05 4.795166008020859 0.25561143284739907 AVAS(ph)SPAATNSEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVASSPAATNSEVK 14 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 AVAS(0.498)S(0.498)PAAT(0.003)NSEVK 159.41 0.00045005 8325200.0 30660.0 25779.0 28909.0 34446.0 37670.0 38693.0 44136.0 33796.0 35950.0 30178.0 True False 35850.13243739695 28338.16875252423 29598.30019799302 32516.10229543877 30288.833916357642 36663.870964866415 39955.11856303151 32908.890809821925 36475.70073928191 35649.032511083446 1.0056411047410887 0.7949211172480982 0.8302693821716136 0.912117384541344 0.8496397176260171 1.0284674893622274 1.1207911056382605 0.9231355942013406 1.023189078916558 1.0 15.12157530305165 -6.765130008353788 24.99825828073504 1.0206673047113757 0.873059658383412 0.5084595690217449 0.06900727339787799 77.40607092656802 524301.7044652348 0.02371060594766588 0.021714045018040067 1.717394199147742e-07 6.765130008353788 -0.14760764632796364 AVASS(ph)PAATNSEVK ddPTM_PC-9_AZD4547_30min_R2 1 AVASSPAATNSEVK 14 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 AVAS(0.03)S(0.854)PAAT(0.108)NS(0.008)EVK 111.31 0.00041142 14753000.0 46053.0 38180.0 40093.0 69515.0 61551.0 52454.0 40576.0 58361.0 45013.0 54029.0 True False 60696.896038092826 50520.938349406744 39561.34062369917 53489.39074604382 53005.706097596965 49174.04308791548 44187.18539387245 49342.648452363974 47392.29528413916 52137.461155147736 1.1641705348381732 0.9689949842219852 0.7587891651642713 1.0259301001802348 1.016652996199135 0.9431614428172119 0.8475131779505469 0.9463953050098256 0.9089874005009915 1.0 15.670032711788926 -6.995665412563019 24.443461582708053 0.9175541141447011 0.9758571077119802 0.07178474346586139 0.0997032577664487 293.19887730417656 1653374.7878001153 0.03655031466883199 0.032101564140161645 1.0100307302866291e-07 6.995665412563019 0.05830299356727908 AVASS(ph)PAATNSEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AVASSPAATNSEVK 14 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 AVAS(0.037)S(0.93)PAAT(0.028)NS(0.005)EVK;AVAS(0.036)S(0.937)PAAT(0.025)NS(0.002)EVK 127.79 2.7688000000000003e-05 11054700.0 58729.0 51143.0 56185.0 61696.0 73172.0 75891.0 84464.0 70185.0 75245.0 64735.0 True False 68670.65974937657 56220.13904768793 57524.663482799064 58239.37314113074 58834.47186959707 71911.14236153 76462.95845359545 68342.71811715455 76345.31577544568 76470.9430580219 0.8979967684885629 0.735183022459017 0.7522421089949491 0.7615882688532026 0.769370293040021 0.9403721137186424 0.9998955864265935 0.8937083208886268 0.9983571893120121 1.0 16.2226240454019 -6.79897435730244 5.170579631792751 0.964211339314464 0.7771987041846129 0.7623466504854592 0.051182833996247123 0.0908976608263124 5.812067177458871 0.017662219714627624 0.01595362886165376 1.5886405463044786e-07 6.79897435730244 -0.1870126351298511 AVASS(ph)PAATNSEVK ddPTM_PC-9_Lapatinib_30min_R1 2 AVASSPAATNSEVK 14 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 AVAS(0.141)S(0.859)PAATNSEVK;AVAS(0.066)S(0.933)PAATNSEVK 228.03 1.3122000000000001e-20 20894000.0 81357.0 81988.0 93238.0 78301.0 100231.0 103345.0 109626.0 104525.0 108076.0 88435.0 True False 80196.83426095363 81798.16182332775 85572.33154908833 84059.51674447903 94335.60964172787 98925.17525896152 115301.89787586252 109381.61308727281 95903.34278926629 103720.87191776975 0.7731986125659833 0.7886374295829061 0.825025185065262 0.8104397426500781 0.909514236599529 0.9537634367110771 1.1116556942104598 1.0545766832156107 0.924629161094006 1.0 16.662346713644197 -6.5728132757220425 1.6470381639445217 1.0261879646558125 0.7954392303693418 0.8135748716599127 0.04771178388256282 0.15367515707611815 0.8527745287968497 0.019718261629045546 0.02079840995241043 2.6741559109589614e-07 6.5728132757220425 -0.2307487342864707 AVDALLTHCK ddPTM_PC-9_Lapatinib_30min_R1 1 AVDALLTHCK 10 0 O76021;J3QSV6;I3L3C4;I3L3U9;I3L1A3 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 0 76.143 0.022121000000000002 0.0 34821.0 35077.0 44061.0 37311.0 38851.0 39207.0 32969.0 32246.0 37549.0 36009.0 False True 34324.44615461066 34995.78136162447 40438.474660378524 40054.9754058473 36565.86056400486 37530.20800598094 34675.973501444074 33744.26687981055 33319.83621150074 42233.1076710235 0.8127378743232045 0.8286338205141218 0.9575064893489643 0.9484259533505597 0.8658103222911303 0.8886442432397826 0.821061376102227 0.7990003279574613 0.788950613605017 1.0 15.366086789525907 -7.252221009813714 23.33606910486538 0.8355031084023963 0.8866205820497151 0.023698281031950263 0.06990735055544903 641.4085775326197 1623711.9180594117 0.027143928583643635 0.020689937629267966 5.594728167336123e-08 7.252221009813714 0.05111747364731878 AVDIT(ph)TPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVDITTPK 8 0 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 AVDIT(0.743)T(0.257)PK 99.01299999999999 0.013032 41703000.0 613230.0 553980.0 509660.0 677230.0 684600.0 573250.0 629630.0 585670.0 505100.0 457520.0 True False 717037.7271554134 608975.4732737273 521812.2272963144 639286.9987092841 550457.5444422207 543187.7608510505 569986.8882735532 570296.783068658 512486.13194468134 540464.7542736717 1.3267058054859422 1.1267626028493327 0.9654879863490371 1.1828467881655285 1.0184892540901733 1.0050382685565469 1.0546236063803203 1.055196992142582 0.9482322906207072 1.0 19.043841011929445 -4.82942368273683 2.9408565191323057 1.0358097186995534 1.3600431924254273 0.6822759632452318 0.061696969934115706 0.19781825645246087 2.6259218989339352 0.01543535774281204 0.1457874270543499 1.4810724968166676e-05 4.82942368273683 0.32423347372587386 AVDITT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 AVDITTPK 8 0 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 AVDIT(0.027)T(0.973)PK 112.3 0.0091256 59051000.0 266580.0 230430.0 251630.0 334060.0 322960.0 307390.0 310260.0 287030.0 273460.0 323500.0 True False 351346.8947915398 304911.99119575165 248293.22178787852 257047.6281755508 278122.5786953895 288168.8547068739 337872.53894673934 242676.1087932353 287914.5373203456 312174.363465737 1.125482858012145 0.9767361669633629 0.7953671116082219 0.82341043422601 0.8909206239990142 0.9231022416691885 1.0823199419571263 0.7773736001222612 0.9222875771217706 1.0 18.25199253891636 -4.870578719680682 3.5745609094671105 0.8972441924948459 1.1321837456811696 0.37356262507562443 0.0877387175628766 0.2633809311980201 5.6764181432665 0.022603510674426175 0.14249608941151484 1.3471665174757968e-05 4.870578719680682 0.23493955318632376 AVDITT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AVDITTPK 8 0 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 AVDIT(0.271)T(0.729)PK;AVDIT(0.032)T(0.968)PK 106.2 0.009364399999999998 83797000.0 1264300.0 1170160.0 974920.0 1266060.0 1371660.0 1165650.0 1326000.0 1086560.0 1031410.0 941600.0 True False 1478321.0189367556 1286325.7514819747 998165.7902046877 1195126.7628219018 1102893.069543699 1104521.2619904522 1200391.6805913493 1058038.9513054823 1046492.4200139833 1112304.6262985007 1.3290612876944288 1.1564509587293341 0.8973852725276876 1.0744599407079827 0.9915386877548813 0.9930024885952783 1.0791932823168977 0.9512132974097192 0.9408325698477713 1.0 20.085120521651966 -4.967481145665653 3.393417518630345 0.995693675331608 1.3233082569246335 0.796872327794667 0.05409058718896588 0.1028106808891034 2.3403756194017338 0.013707472876846007 0.06908086326172767 1.0777520418924323e-05 4.967481145665653 0.3276145815930255 AVDITT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 AVDITTPK 8 0 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 AVDIT(0.204)T(0.796)PK 92.051 0.020208 60131000.0 183840.0 173660.0 154790.0 165920.0 155600.0 145770.0 131650.0 134890.0 133280.0 113060.0 True False 181218.4078878729 173257.90093963835 142063.763706679 178122.31029289443 146447.91392137017 139535.7569064667 138466.19283160294 141157.48184015555 118268.60289937991 132602.27035701985 1.3666312605354223 1.3065982993591045 1.0713524234855474 1.3432825080092212 1.1044148303575207 1.0522878419108441 1.0442218859360024 1.0645178356305782 0.8919048111389962 1.0 17.016745951280775 -5.749075737633993 0.38301200143824765 0.9520150245580675 1.4635244375111827 0.6915664757835311 0.08381070502577408 1.6948191511304116 0.3377151446269162 0.08080047863850501 0.3741130261118672 1.7820679613334618e-06 5.749075737633993 0.5115094129531151 AVDS(ph)SSEEIEVEVPVVDRR ddPTM_PC-9_AZD4547_30min_R2 1 AVDSSSEEIEVEVPVVDRR 19 1 Q9Y6X4;D6RB01 Q9Y6X4 FAM169A Soluble lamin-associated protein of 75 kDa 1 AVDS(0.718)S(0.068)S(0.214)EEIEVEVPVVDRR 115.63 0.00038945 0.0 787.69 1154.5 912.45 2143.8 742.91 2179.8 1107.0 1081.6 927.71 821.16 True False 1038.1590350301894 1527.6695475220047 900.3503168157613 1649.5800313798284 639.7697700600434 2043.496761410727 1205.5208554568412 914.4635726954102 976.7468566424982 792.4114383416514 1.310126261179212 1.9278741744554975 1.136215699637051 2.0817216304096373 0.8073706904066723 2.5788329932330747 1.5213319711534452 1.1540262147265163 1.2326258927895104 1.0 9.63010589524149 -7.709015000551164 4.863659664522283 1.1416075554946463 1.6446576204201055 0.18787650392090816 0.4742018272719094 0.3278417542596976 16.224407755858604 0.22619044286528844 0.12243976586331125 1.9542719539674385e-08 7.709015000551164 0.5030500649254592 AVDSQILPK ddPTM_PC-9_Lapatinib_30min_R1 1 AVDSQILPK 9 0 Q02878 Q02878 RPL6 60S ribosomal protein L6 0 94.85 0.025870999999999998 12792000.0 130550.0 125990.0 131620.0 123230.0 130000.0 107010.0 113170.0 103230.0 111280.0 115190.0 False True 128688.3330600619 125698.27789580252 120798.71166789281 132292.74528322945 122353.65558983371 102433.43175249382 119029.38885493716 108026.44265964301 98746.47456965053 135100.43801897293 0.9525382370854302 0.9304061462639373 0.8941400445417383 0.9792177377296943 0.9056495847382144 0.758202069915632 0.8810436931242309 0.7996009801572386 0.7309115796929022 1.0 17.043672826574692 -6.5792987486370045 7.680114399384621 0.824707011574326 0.9361575105583103 0.322916570656511 0.07189060888678521 0.2556972802117326 29.87878635874499 0.022463184788866854 0.022485108836212193 2.6345184924770656e-07 6.5792987486370045 0.11145049898398429 AVDTWSWGER ddPTM_PC-9_AZD4547_30min_R2 1 AVDTWSWGER 10 0 Q08380 Q08380 LGALS3BP Galectin-3-binding protein 0 97.965 0.022768 4139300.0 18689.0 22894.0 26022.0 26697.0 25934.0 24382.0 25349.0 22069.0 26198.0 22024.0 False True 24631.713244651088 30294.03778342898 25676.931277527237 20542.419114538345 22333.511753425275 22857.389685620845 27605.011892480114 18658.743145169214 27582.77279572299 21252.946463583863 1.158978746163814 1.4254041356259326 1.2081586579782577 0.9665680544453927 1.0508430815319147 1.0754927428432635 1.2988792843279533 0.8779367687741687 1.2978328836890947 1.0 14.375375246857326 -5.529776223898667 20.200104292241704 1.0838664444811839 1.2983390399620267 0.2809161765083322 0.1385421141668829 17.355039010540118 50825.58792142964 0.03523876036592066 0.06142543868905219 2.9527302689414502e-06 5.529776223898667 0.21447259548084285 AVEFSSGAKS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 1 AVEFSSGAKSPSK 13 1 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 AVEFS(0.006)S(0.006)GAKS(0.749)PS(0.24)K 63.754 0.020853 29306000.0 100780.0 81658.0 121270.0 135360.0 138700.0 108940.0 98065.0 122240.0 98834.0 134330.0 True False 132825.94364577733 108052.35159077679 119661.88056358956 104154.84329115298 119443.8991362725 102127.96457844056 106792.59502292269 103350.61679575362 104058.16346638986 129627.1475868698 1.0246768992333481 0.8335626726520797 0.9231236109966702 0.8034956043552025 0.9214420077879676 0.7878593834674898 0.8238443644789414 0.7972914525986393 0.8027497742836248 1.0 16.98400836540211 AVEHINK ddPTM_PC-9_AZD4547_30min_R2 4 AVEHINK 7 0 P06733;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8Y6I8 P06733 ENO1 Alpha-enolase;Enolase 0 ;;; 102.77 0.0090388 53090300.0 628280.0 450383.0 456259.0 374931.0 386364.0 395039.0 377690.0 356510.0 689490.0 836720.0 False True 828059.9709641718 595960.4970304044 450208.7075456649 288496.4505762058 332724.0277280949 370337.14888105844 411303.6783175198 301419.5712848005 725935.0337782664 807426.6874777465 1.0255543739220212 0.7380985868724207 0.5575846259826198 0.3573035856387358 0.4120795520983632 0.45866349802967754 0.5094006486240347 0.37330890340815975 0.8990723802379568 1.0 19.62297174673393 -8.403173821591986 5.226803300564106 0.9944011134160712 0.5452670254703924 0.4126626289391574 0.18993834089690598 0.22200329033581226 7.938822230992603 0.19725884096541157 0.05133166541143727 3.952084105878042e-09 8.403173821591986 -0.4491340879456788 AVEHINK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 AVEHINK 7 0 P06733;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8Y6I8 P06733 ENO1 Alpha-enolase;Enolase 0 ;;;; 115.46 0.0068980000000000005 50992300.0 462348.0 700943.0 622927.0 546743.0 1170690.0 960192.0 434962.0 859389.0 1076530.0 1101650.0 False True 540614.3846107508 770527.9886690968 637779.9421438017 516110.7622747209 941301.6983684804 909837.8411985898 393759.2505078245 836830.9493479134 1092272.214655331 1301370.424343401 0.41541929530442084 0.5920896727446855 0.49008332309810243 0.3965902041573763 0.723315729910958 0.6991382500932762 0.30257276724764465 0.6430382416060605 0.8393246029134485 1.0 20.31160024106353 -8.321233637700221 2.429585277046458 0.9854140836176671 0.527169118314047 0.6187298864812254 0.12642098053591774 0.18931552582744815 2.095417216653044 0.1206433516590376 0.03395967524344629 4.772724459959748e-09 8.321233637700221 -0.45824496530362013 AVEHINK ddPTM_PC-9_Lapatinib_30min_R1 3 AVEHINK 7 0 P06733;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8Y6I8 P06733 ENO1 Alpha-enolase;Enolase 0 ;; 101.28 0.0094404 42009800.0 231427.0 253282.0 154958.0 211125.0 243216.0 146266.0 276285.0 409232.0 289693.0 234626.0 False True 228126.8085414862 252695.54109060025 142217.9513951778 226651.8367923538 228910.5130610538 140010.5441426994 290589.6854271124 428246.4126948652 257064.72373747078 275180.7914805062 0.829007022307539 0.9182891717516599 0.5168164195982863 0.8236470124711078 0.8318549846066193 0.5087947577642524 1.0559955288437992 1.5562365759283099 0.9341666704075936 1.0 18.07002024315782 -7.510401953687952 24.555535752923014 1.208344180566265 0.7475260443136611 0.49023775048342844 0.1996332259292088 353.7034691385969 696127.655671654 0.08336202472877939 0.05298307142216349 3.0874365866215963e-08 7.510401953687952 -0.4608181362526038 AVELAANTK ddPTM_PC-9_Lapatinib_30min_R1 4 AVELAANTK 9 0 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 ;;; 134.25 0.0051882 39384700.0 282911.0 287266.0 290245.0 284964.0 286127.0 279821.0 285971.0 251932.0 258604.0 268469.0 False True 278876.6372604772 286600.85322657006 266382.17647810053 305921.2031720366 269297.5724073261 267853.70812460996 300777.17911315046 263637.68044298276 229477.29429915428 314873.50893754297 0.8856783100028717 0.9102094812409863 0.8459974209228857 0.9715685648001525 0.8552563641063334 0.8506708266072023 0.9552317695065653 0.8372812350348497 0.7287919999159804 1.0 18.26441285962656 -7.902267544772234 24.99985726785038 0.8372262556501878 0.8946459417718262 0.0446684404216644 0.07349537762547485 28.10186554110811 7154.520755524367 0.03766956763181953 0.018095874364017807 1.2523694218238044e-08 7.902267544772234 0.05741968612163839 AVFHEEEQR ddPTM_PC-9_Lapatinib_30min_R1 2 AVFHEEEQR 9 0 A0A2R8Y611;O14617-3;O14617-4;O14617-2;O14617;O14617-5 A0A2R8Y611 AP3D1 AP-3 complex subunit delta-1 0 ; 131.22 2.7496e-06 0.0 42051.0 38053.0 45201.0 36224.0 37068.0 39518.0 31189.0 39682.0 41676.0 29054.0 False True 41451.34502879103 37964.89061646937 41484.748260905784 38888.03379972161 34887.73311849195 37827.907260957356 32803.81381105095 41525.77058626319 36982.01001226414 34075.94518797847 1.2164400664494115 1.114125827091155 1.217420324867204 1.1412165850484108 1.0238229028141492 1.1101058841444118 0.9626677596201703 1.2186241748303117 1.085282001959285 1.0 15.056466054161659 -6.042666909619041 6.719547153023284 1.0750265464894158 1.1765401366142996 0.35478786877106516 0.07071026924630379 0.26655660097357897 33.13598973709341 0.020341097637497165 0.026889183906868567 9.064275361391107e-07 6.042666909619041 0.10151359012488381 AVFPS(ph)IVGRPR ddPTM_PC-9_AZD4547_30min_R2 2 AVFPSIVGRPR 11 1 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;Q6S8J3;C9JTX5;A5A3E0;P63267-2;P0CG38;F8WCH0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;POTEE;POTEF;ACTG2;POTEI;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Actin, gamma-enteric smooth muscle;POTE ankyrin domain family member I;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 1 AVFPS(1)IVGRPR;AVFPS(1)IVGRPR 143.76 7.4992e-05 106452000.0 31411.0 46408.0 45101.0 70750.0 56415.0 50603.0 33273.0 48925.0 33403.0 43026.0 True False 41399.04461061239 61408.47844209716 44502.9312715301 54439.680576603634 48582.75104378373 47438.78641052708 36234.23254165808 41364.765434655106 35168.61438642395 41519.67283609515 0.997094673025027 1.4790212505892306 1.071851684554736 1.3111779755951367 1.1701140140379018 1.1425616622221102 0.872700338576797 0.9962690601621172 0.8470349591928887 1.0 15.341507455239398 -7.100652683536633 3.1572366663504217 0.9283608366839241 1.217493416849927 0.501668361487269 0.13045712630190262 0.2013778320332158 3.8231947207580785 0.04962963025980131 0.03785278755596691 7.931353676646654e-08 7.100652683536633 0.28913258016600285 AVFPS(ph)IVGRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AVFPSIVGRPR 11 1 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;Q6S8J3;C9JTX5;A5A3E0;P63267-2;P0CG38;F8WCH0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;POTEE;POTEF;ACTG2;POTEI;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Actin, gamma-enteric smooth muscle;POTE ankyrin domain family member I;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 1 AVFPS(1)IVGRPR;AVFPS(1)IVGRPR;AVFPS(1)IVGRPR;AVFPS(1)IVGRPR 119.21 0.00046579 63467000.0 119407.1 133351.3 114030.6 139171.8 143524.9 134617.19999999998 150523.2 125085.5 125161.1 115612.9 True False 139620.36363227354 146589.53577596025 116749.5219674587 131374.4552470632 115402.22614711568 127557.63705196323 136264.55280240398 121802.13816404219 126991.34430596189 136572.603578787 1.022316042702725 1.0733451068126896 0.8548531616746061 0.9619385718986819 0.844988109789835 0.9339913987828229 0.9977444174870306 0.8918489870757723 0.9298449394552414 1.0 17.059308582917843 -5.248565682832347 24.9621803130611 0.92414786505691 1.0478305883420393 0.4716733726774305 0.05112799389534197 611.6336946070047 1185956.7927973531 0.012478033113181162 0.032561435596489996 5.642016048661315e-06 5.248565682832347 0.1236827232851293 AVFPS(ph)IVGRPR ddPTM_PC-9_Lapatinib_30min_R1 2 AVFPSIVGRPR 11 1 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;Q6S8J3;C9JTX5;A5A3E0;P63267-2;P0CG38;F8WCH0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;POTEE;POTEF;ACTG2;POTEI;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Actin, gamma-enteric smooth muscle;POTE ankyrin domain family member I;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 1 AVFPS(1)IVGRPR;AVFPS(1)IVGRPR 136.01 3.6454e-05 87980000.0 65913.0 55543.0 57115.0 33423.0 61527.0 51545.0 53319.0 59349.0 44706.0 36364.0 True False 64973.068533036196 55414.393596051734 52419.22517027571 35881.038915859535 57908.10282673614 49340.54050726372 56079.59692812933 62106.57120417653 39670.739504949604 42649.46894801575 1.523420341112103 1.2992985601671805 1.2290709934552304 0.84130095405394 1.357768437804436 1.156885225637945 1.3148955499653041 1.4562097192787207 0.9301578773068234 1.0 15.380240157415782 -1.5228835408575918 0.02361903902270811 7.674163505179266e-10 2.8477405213378044 0.1716416106631553 0.1954563978013137 5219.2717110019175 9.520883364496001 403.3194909728149 809.5263596618628 0.029999668735088015 1.5228835408575918 2.847740520570388 AVFPSIVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVFPSIVGR 9 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;Q6S8J3;C9JTX5;A5A3E0;P63267-2;P0CG38;F8WCH0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;POTEE;POTEF;ACTG2;POTEI;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Actin, gamma-enteric smooth muscle;POTE ankyrin domain family member I;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 0 93.195 0.029688 12566000.0 36648.0 46722.0 59886.0 49828.0 53779.0 47085.0 43783.0 39233.0 43611.0 42891.0 False True 42851.782569006 51360.25138505908 61313.909358919766 47036.298704555615 43241.39100578172 44615.77971159473 39635.557278530185 38203.175320799615 44248.728371093865 50666.79877503078 0.8457566612659942 1.0136865289853292 1.2101397925525939 0.9283455801777569 0.8534462814155847 0.8805723035650308 0.7822786960454875 0.7540080732242079 0.8733278881021428 1.0 15.628753059065437 -5.996148381717026 24.934713488606604 0.8467977436369031 1.0300767526688925 0.3420593542404696 0.10237068338637352 114.31185003415736 740018.9632096065 0.02944000772610099 0.04344772591648144 1.008908122091426e-06 5.996148381717026 0.18327900903198946 AVFPSIVGR ddPTM_PC-9_Lapatinib_30min_R1 1 AVFPSIVGR 9 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;Q6S8J3;C9JTX5;A5A3E0;P63267-2;P0CG38;F8WCH0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;POTEE;POTEF;ACTG2;POTEI;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Actin, gamma-enteric smooth muscle;POTE ankyrin domain family member I;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 0 122.18 0.007243600000000001 53188000.0 49854.0 46910.0 44749.0 41148.0 45839.0 43473.0 50624.0 40097.0 37242.0 45738.0 False True 49143.07281789612 46801.38277714179 41069.90995613533 44174.16118570406 43142.84014294146 41613.761130512656 53245.063014865606 41960.05300129518 33047.413784354096 53643.752357945865 0.9161005831579735 0.872447968681472 0.7656047191123075 0.8234726178539011 0.8042472468194336 0.775742920682332 0.9925678326821743 0.7821983205296774 0.6160533581588467 1.0 15.71112253623366 -5.030489596432689 5.6373658771255215 0.8162731627500748 0.90720328656441 0.07966110697145334 0.1051622797219438 0.398945572343725 38.980507403473865 0.026302820455212914 0.08121303124889075 9.322028010845311e-06 5.030489596432689 0.09093012381433518 AVFPSIVGRPR ddPTM_PC-9_AZD4547_30min_R2 2 AVFPSIVGRPR 11 1 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;Q6S8J3;C9JTX5;A5A3E0;P63267-2;P0CG38;F8WCH0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;POTEE;POTEF;ACTG2;POTEI;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Actin, gamma-enteric smooth muscle;POTE ankyrin domain family member I;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 0 ; 163.38 0.0019866 86556000.0 84115.0 72066.0 99885.0 174504.0 151052.0 132102.0 102365.0 153834.0 98592.0 129252.0 False True 110861.82029931109 95359.92517256031 98560.4596363004 134274.7988599244 130081.03714731208 123841.64105692234 111475.28669271868 130062.49005364838 103803.37184044288 124726.92682124671 0.8888363012278295 0.7645496253525598 0.7902099582518619 1.0765502067758095 1.0429266595635651 0.9929022081527501 0.8937547772060502 1.0427779579629053 0.8322450852109058 1.0 16.92841343116728 -5.745893573738427 24.998445581795355 0.9839930136406465 0.8095336569793217 0.5166973382418197 0.07462409722510706 186.98433148997935 300677.8552520096 0.020141782946263995 0.03473000223856001 1.795173490114077e-06 5.745893573738427 -0.17445935666132484 AVFPSIVGRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AVFPSIVGRPR 11 1 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;Q6S8J3;C9JTX5;A5A3E0;P63267-2;P0CG38;F8WCH0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;POTEE;POTEF;ACTG2;POTEI;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Actin, gamma-enteric smooth muscle;POTE ankyrin domain family member I;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 0 ; 160.75 0.0012734000000000003 142861000.0 107945.0 98343.0 111758.0 128811.0 144407.0 129334.0 139799.0 136295.0 121067.0 100985.0 False True 126217.95648906767 108105.84311375525 114422.73456457509 121594.13728089641 116111.4849843233 122551.49736050547 126556.22666288828 132717.4006664896 122837.37583873843 119292.78110317983 1.0580519233590342 0.906222841935853 0.9591756810968092 1.0192916633884666 0.9733320315828252 1.0273169610699835 1.0608875532327986 1.1125350540004462 1.0297134051430386 1.0 16.86414721670085 -6.947346170848296 2.7954881725919885 1.0597496517543739 0.9791777822819733 0.31963397569215724 0.04575289917117033 0.2794584946163695 4.436572913134636 0.017817710688512768 0.014839412542182955 1.1288957269052954e-07 6.947346170848296 -0.08057186947240058 AVFPSIVGRPR ddPTM_PC-9_Lapatinib_30min_R1 2 AVFPSIVGRPR 11 1 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;Q6S8J3;C9JTX5;A5A3E0;P63267-2;P0CG38;F8WCH0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;POTEE;POTEF;ACTG2;POTEI;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Actin, gamma-enteric smooth muscle;POTE ankyrin domain family member I;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 0 ; 169.99 0.00037096 212480000.0 111050.0 106436.0 114301.0 101076.0 110435.0 110605.0 95325.0 85724.0 112610.0 90651.0 False True 109466.40663592434 106189.55398140813 104903.61299461915 108509.46621965164 103939.43042356383 105874.6819828479 100260.46207119283 89707.04999084791 99926.67596412964 106319.90456513508 1.0295946660567366 0.9987739776078609 0.9866789612320592 1.0205940897282801 0.977610268262488 0.9958124249254342 0.9430074498399307 0.8437465247712899 0.9398679990623136 1.0 16.6980521891723 -7.345380208242796 3.6813029279990537 0.9151551874899827 1.000881993206117 0.42701945568894506 0.03881247300809116 0.1941536538996584 4.995796197813171 0.016522637873835195 0.010809328495202499 4.514605348502448e-08 7.345380208242796 0.08572680571613434 AVFVDLEPT(ph)VIDEVR ddPTM_PC-9_Lapatinib_30min_R1 2 AVFVDLEPTVIDEVR 15 0 Q9BQE3;F5H5D3;A0A1W2PQM2;F8VVB9;F8VQQ4;F8VRZ4;F8VS66;F8VWV9;F8VX09;F8VRK0;P68363;P68363-2;Q71U36-2;Q71U36 Q9BQE3;P68363;Q71U36-2 TUBA1C;TUBA1B;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-1B chain;Tubulin alpha-1A chain 1 AVFVDLEPT(1)VIDEVR;AVFVDLEPT(1)VIDEVR 159.13 7.814e-10 315860.0 3180.45 3588.8900000000003 2363.1 2184.2 839.81 2954.1499999999996 2954.39 2103.2 3398.98 1727.75 True False 3135.096199776902 3580.5801457057432 2168.8150398297926 2344.833354277604 790.4140269299866 2827.8078909599967 3107.3538582587084 2200.922350109084 3016.151079553832 2026.3892854178368 1.54713421667666 1.7669754629439012 1.070285485339303 1.1571485159102115 0.39006030707816586 1.3954909411085388 1.533443687557783 1.0861300767563322 1.4884361564969035 1.0 10.984695638560522 -10.86328371495075 16.77102620017331 0.9999999071968511 1.2560249807504482 0.0462550040349603 0.36321847970591803 0.0 0.0 0.3721356334752932 0.09025614846322197 1.3699864919815286e-11 10.86328371495075 0.25602507355359716 AVFVDLEPTVIDEVR ddPTM_PC-9_AZD4547_30min_R2 4 AVFVDLEPTVIDEVR 15 0 Q9BQE3;F5H5D3;A0A1W2PQM2;F8VVB9;F8VQQ4;F8VRZ4;F8VS66;F8VWV9;F8VX09;F8VRK0;P68363;P68363-2;Q71U36-2;Q71U36 Q9BQE3;P68363;Q71U36-2 TUBA1C;TUBA1B;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-1B chain;Tubulin alpha-1A chain 0 ;;; 260.57 8.0997e-50 31324000.0 51926.3 53711.5 74047.4 89206.0 81320.0 73994.1 55248.7 79096.2 58606.2 66617.1 False True 68437.78326586372 71072.6919893703 73065.48309428837 68640.93491896115 70030.12168537594 69367.2372297923 60165.72726908617 66873.6997398584 61704.00408507138 64284.855605667086 1.0646019598406087 1.1055899763599193 1.1365893631694992 1.0677621388778549 1.0893719994480686 1.0790603257367692 0.9359238144385318 1.040271446669674 0.9598528845358689 1.0 15.97219128326144 -7.14038755031801 6.094986688504417 0.9877635499718402 1.093462952270341 0.7327174796780782 0.031533165697877404 0.12184934206778339 5.588230873957096 0.011730333837403588 0.009062516858611262 7.237897852623936e-08 7.14038755031801 0.10569940229850072 AVFVDLEPTVIDEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AVFVDLEPTVIDEVR 15 0 Q9BQE3;F5H5D3;A0A1W2PQM2;F8VVB9;F8VQQ4;F8VRZ4;F8VS66;F8VWV9;F8VX09;F8VRK0;P68363;P68363-2;Q71U36-2;Q71U36 Q9BQE3;P68363;Q71U36-2 TUBA1C;TUBA1B;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-1B chain;Tubulin alpha-1A chain 0 ;;; 248.21 1.0987e-39 38199000.0 59357.0 60208.0 63766.0 69252.0 65139.0 65512.0 62426.0 58115.0 50831.0 50955.0 False True 69404.96774581131 66185.05233919014 65286.423273901644 65372.03495801326 52375.48055422406 62076.43539271522 56512.55735489865 56589.54282793232 51574.30721219578 60192.73814044195 1.1530455315701928 1.0995521118306149 1.0846229178273148 1.0860452103954292 0.8701295566920608 1.0312944270433124 0.9388600535673143 0.9401390363052992 0.8568194238292066 1.0 15.877301825326517 -6.154761762768578 5.930711282412032 0.9414364537246791 1.1066499049216902 0.7145257804892259 0.05158120306898257 0.12970472180575524 6.127073387472505 0.01511286826354158 0.019645037267276202 7.002260076931166e-07 6.154761762768578 0.16521345119701114 AVFVDLEPTVIDEVR ddPTM_PC-9_Lapatinib_30min_R1 4 AVFVDLEPTVIDEVR 15 0 Q9BQE3;F5H5D3;A0A1W2PQM2;F8VVB9;F8VQQ4;F8VRZ4;F8VS66;F8VWV9;F8VX09;F8VRK0;P68363;P68363-2;Q71U36-2;Q71U36 Q9BQE3;P68363;Q71U36-2 TUBA1C;TUBA1B;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-1B chain;Tubulin alpha-1A chain 0 ;;; 295.34 1.8967999999999994e-103 189301000.0 78421.0 73698.0 84438.0 68602.0 76268.0 86049.0 71506.0 61485.0 74424.0 68690.5 False True 77302.70215935004 73527.35680899162 77495.83358010577 73647.21992956339 71782.06618865728 82368.88486001614 75208.23079845485 64341.81756202791 66041.58540053613 80563.56140066212 0.9595243906225168 0.9126626918008535 0.961921645875363 0.9141504999176726 0.8909991681185451 1.022408684869028 0.9335266402192188 0.7986466392919307 0.8197451087358877 1.0 16.297839840221684 -7.6401715042776415 8.520875404410532 0.8572412238229326 0.9424492188606662 0.20507821899586398 0.06052169259801077 0.3137320400339511 21.97247461880314 0.027554562910526662 0.015845376415992266 2.289963160421979e-08 7.6401715042776415 0.08520799503773369 AVFVDLEPTVIDEVRT(ph)GTYR ddPTM_PC-9_AZD4547_30min_R2 1 AVFVDLEPTVIDEVRTGTYR 20 1 Q9BQE3;F5H5D3;A0A1W2PQM2;F8VVB9;F8VQQ4;F8VRZ4;F8VS66;F8VWV9;F8VX09;F8VRK0;P68363;P68363-2;Q71U36-2;Q71U36 Q9BQE3;P68363;Q71U36-2 TUBA1C;TUBA1B;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-1B chain;Tubulin alpha-1A chain 1 AVFVDLEPT(0.236)VIDEVRT(0.565)GT(0.099)Y(0.099)R 56.681000000000004 0.014672999999999999 1623700.0 6381.5 5279.3 7523.5 8348.3 9973.2 6790.1 6444.4 9692.7 6735.8 5759.0 True False 8410.684256554168 6985.730482661689 7423.73347423243 6423.728414949256 8588.593329963025 6365.513973600772 7017.939115542974 8194.915931088022 7091.840636591758 5557.379162903175 1.5134263849941143 1.2570188712861448 1.3358335389076228 1.1558916940253363 1.5454395099211378 1.1454165330471042 1.2628145227860974 1.4746008308720469 1.2761124315453367 1.0 12.440188958957876 -8.55515925904401 22.251882981093264 0.9999999965442957 1.3288891722168819 0.3644747668218338 0.13241966651760698 3146.277853356413 2168817.089656393 0.12145879605613451 0.03136052627948241 2.785099664407553e-09 8.55515925904401 0.32888917567258613 AVGDGIVLCK ddPTM_PC-9_Lapatinib_30min_R1 1 AVGDGIVLCK 10 0 A0A0A0MSQ0;P13797-3;P13797-2;P13797;U3KQI3 A0A0A0MSQ0 PLS3 Plastin-3 0 130.75 0.00021494 0.0 26963.0 24115.0 27955.0 24781.0 27988.0 26980.0 24852.0 23879.0 26720.0 25560.0 False True 26578.50267559138 24059.163199121198 25656.647809420614 26603.477406992646 26341.80086652511 25826.12829345183 26138.714958230095 24988.505514575336 23710.512225926144 29978.011943440837 0.8865999094848827 0.8025603313693163 0.8558488754299888 0.8874330111411362 0.878704062037999 0.8615023685419061 0.8719295664951265 0.8335611301283372 0.7909301080625523 1.0 14.87161709057235 -11.26177594903803 2.721817641550237 1.0286252254440682 0.8529043360161136 0.6588738270525765 0.031917529708450604 18737469.06175587 15280904.873571007 3625403.3777914126 0.008648971664243438 5.47298239269185e-12 11.26177594903803 -0.1757208894279546 AVGMPS(ph)PVSPK ddPTM_PC-9_AZD4547_30min_R2 3 AVGMPSPVSPK 11 0 Q9UHB7 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 AVGMPS(0.998)PVS(0.002)PK;AVGMPS(0.996)PVS(0.004)PK;AVGMPS(0.965)PVS(0.035)PK 114.86 0.0014162 10005100.0 92858.0 83973.0 115628.0 136541.0 134134.0 117112.0 101249.0 118306.0 103937.0 117580.0 True False 122384.91243361408 111115.63006848453 114094.69717000687 105063.58198742098 115511.80942137547 109788.96812658611 110259.96485469701 100024.52610142667 109430.89762840899 113463.55998856685 1.0786274681135175 0.9793067490538909 1.0055624658833515 0.9259676146069074 1.01805204625181 0.9676143436504988 0.9717654272949602 0.8815563878967454 0.9644585243000994 1.0 16.79186950970739 -1.522878753591857 0.8096147598269601 0.9586582844449365 31.400624176970034 0.4339774648080973 0.03784048800270849 500.41313118423074 1.6697338888967117 0.013445188865681672 27964.464496464025 0.029999999425860575 1.522878753591857 30.441965892525097 AVGMPS(ph)PVSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AVGMPSPVSPK 11 0 Q9UHB7 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 AVGMPS(0.762)PVS(0.238)PK;AVGMPS(0.995)PVS(0.005)PK;AVGMPS(0.96)PVS(0.04)PK 92.611 0.006650799999999999 7403600.0 117919.0 126438.0 149252.0 142880.0 174632.0 150829.0 143086.0 121555.0 128287.0 116005.0 True False 137880.35769358842 138989.92904036865 152810.73372136225 134874.89682321026 140414.11320630088 142919.2617207206 129531.8582270691 118364.3100481685 130162.95467984036 137035.7882049255 1.006163130812222 1.0142600765905099 1.115115516341225 0.9842311894577217 1.0246528665659467 1.0429338466459348 0.9452410930301294 0.8637474312269771 0.949846433438195 1.0 17.064193190419374 -7.329149778303095 4.865445122300091 0.9261355829230777 1.0318622047262105 0.48990782845524816 0.04516016094922758 0.16840232953359432 7.807445100843969 0.019009984445961955 0.01269978076293794 4.68651726934679e-08 7.329149778303095 0.10572662180313275 AVGMPS(ph)PVSPK ddPTM_PC-9_Lapatinib_30min_R1 4 AVGMPSPVSPK 11 0 Q9UHB7 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 AVGMPS(0.999)PVS(0.001)PK;AVGMPS(0.984)PVS(0.016)PK;AVGMPS(0.983)PVS(0.017)PK;AVGMPS(0.961)PVS(0.039)PK 107.34 0.0045027999999999995 7480600.0 153489.0 140923.0 146832.0 125416.0 142781.0 136565.0 127556.0 116912.0 138337.0 123239.0 True False 151300.2187135649 140596.70145178348 134760.03974791052 134639.51101551153 134382.90229824645 130724.43329856386 134160.2255436986 122344.15832823933 122756.03030680916 144540.6969443543 1.0467655263334787 0.9727135984816152 0.9323328487878457 0.9314989747651863 0.9297236358973803 0.9044126399147676 0.9281830541840267 0.8464339865148134 0.849283509087189 1.0 17.141116230230963 -1.5228787452820043 0.5379666308484421 0.8989399754027907 7.006107347885588 0.5059145619800537 0.04119801770917251 98.61537276846431 0.9378487909935511 0.020660763442610388 692.5455086759703 0.029999999999884865 1.5228787452820043 6.107167372482797 AVGMPSPVS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 5 AVGMPSPVSPK 11 0 Q9UHB7 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 AVGMPS(0.028)PVS(0.972)PK;AVGMPS(0.004)PVS(0.996)PK;AVGMPS(0.343)PVS(0.657)PK;AVGMPS(0.32)PVS(0.68)PK;AVGMPS(0.024)PVS(0.976)PK 145.83 0.00021400000000000002 65439800.0 454244.0 400844.0 429392.0 482244.0 443117.0 417173.0 414273.0 434474.0 408454.0 377425.0 True False 598684.1431378517 530408.9840683505 423697.9815202516 371070.0963955289 381597.8533061832 391087.10636205075 451142.4944468581 367336.026519292 430044.0445646325 364211.46562922955 1.6437817027630794 1.4563214893633016 1.1633296079469937 1.01883145209185 1.047737068482773 1.0737913088111861 1.2386828450538818 1.0085789745379494 1.1807537245475437 1.0 18.47441681450571 -5.148217709053093 2.190801706003837 1.0853028932138111 1.6447064053838505 0.8701754095697395 0.07309999476928367 0.11664668376118922 0.9858381688788928 0.019881304375324427 0.09304781695653624 7.1085707620366406e-06 5.148217709053093 0.5594035121700394 AVGMPSPVS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 AVGMPSPVSPK 11 0 Q9UHB7 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 AVGMPS(0.046)PVS(0.954)PK;AVGMPS(0.202)PVS(0.798)PK;AVGMPS(0.021)PVS(0.979)PK;AVGMPS(0.032)PVS(0.968)PK;AVGMPS(0.296)PVS(0.704)PK;AVGMPS(0.007)PVS(0.993)PK 95.273 0.0055692 57862400.0 523612.0 547085.0 411714.0 605909.0 556334.0 491392.0 578963.0 499864.0 470660.0 429613.0 True False 612249.1697915954 601395.9832411926 421530.82319404033 571961.8831134827 447324.3463770359 465622.53847382317 524119.43331086653 486743.0996496873 477542.51209875935 507498.4360853636 1.2064060226751363 1.1850203675111128 0.8306051668760943 1.1270219619302946 0.8814299997208146 0.9174856617597601 1.032750834374408 0.9591026593189635 0.9409733668980892 1.0 18.953043850911243 -5.1823483723640225 8.436051836150579 0.9639029331868343 1.1980774129071454 0.594088842474616 0.07753655306999718 0.2246502882006879 22.059883773664186 0.018577003200149645 0.04954700114342828 6.5713050403988625e-06 5.1823483723640225 0.23417447972031114 AVGMPSPVS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 6 AVGMPSPVSPK 11 0 Q9UHB7 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 AVGMPS(0.01)PVS(0.99)PK;AVGMPS(0.322)PVS(0.678)PK;AVGMPS(0.275)PVS(0.725)PK;AVGMPS(0.452)PVS(0.548)PK;AVGMPS(0.034)PVS(0.966)PK;AVGMPS(0.001)PVS(0.999)PK 131.32 0.00016456 83301700.0 701327.0 649438.0 562278.0 567747.0 608754.0 539705.0 567086.0 564896.0 524800.0 484051.0 True False 691325.9483723807 647934.2662123521 516049.67329584685 609501.008328471 572948.2865764122 516623.0752638037 596446.9383068914 591143.1304142352 465691.49761100445 567718.5703925851 1.2177265011682097 1.141294824589403 0.9089885379986627 1.073597095664834 1.009211811021455 0.909998548940458 1.0506031851211775 1.0412608662870613 0.8202858280449985 1.0 19.114816408184716 -5.089617114246524 4.5082178422259185 0.9835438800926084 1.2031013377977158 0.5515184739857474 0.07421829739582059 0.15013710004200564 5.171140186249512 0.018590002341830603 0.056629549131654716 8.135474455022593e-06 5.089617114246524 0.21955745770510737 AVGPAS(ph)ILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVGPASILK 9 0 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 AVGPAS(1)ILK 67.726 0.044976 1907300.0 20439.0 18677.0 16686.0 19186.0 28458.0 16716.0 18895.0 19116.0 15689.0 14417.0 True False 23898.919011348888 20531.129128007105 17083.857522007387 18111.07062185125 22881.8591874623 15839.38353316381 17105.12881204642 18614.225255076224 15918.421944328056 17030.687975090794 1.4032855893023004 1.2055372723659832 1.0031219846781503 1.0634374047801611 1.343566344526391 0.9300495409422452 1.0043709823739653 1.0929814040572832 0.9346904815360633 1.0 14.0558490951416 -1.5228787584244836 0.7852093826085875 1.043298498377841 83.62708127590867 0.49300217261214496 0.11225284882806101 411.9923797528886 1.5286482442625282 0.041765797520175875 60430.79655156003 0.02999999909203457 1.5228787584244836 82.58378277753083 AVGPSGGGGET(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 AVGPSGGGGETPR 13 0 Q9H330-4;Q9H330 Q9H330-4 TMEM245 Transmembrane protein 245 1 AVGPS(0.001)GGGGET(0.999)PR;AVGPSGGGGET(1)PR 107.93 0.0023323 6696300.0 20626.9 14660.0 28552.0 28109.0 29266.0 17299.8 20674.9 29934.0 22537.0 21773.0 True False 27185.825133827042 19398.558308074997 28173.381824454624 21628.90432972088 25202.921067931846 16218.0407711961 22514.926047411594 25308.388114889432 23728.259809802603 21010.73389718541 1.2939017393137726 0.9232689540022978 1.3409042236372675 1.0294216487420402 1.1995259752115568 0.7718931118997543 1.0715916044430835 1.2045456497966371 1.1293398853136316 1.0 14.358838935246183 -4.7260755280388365 23.92324693701176 1.082167378117252 1.2939046568843966 0.15740331829808274 0.15135513457724598 6734.992925155021 4555675.441574563 0.037070049694492 7.297389222309458 1.8789900137291235e-05 4.7260755280388365 0.21173727876714454 AVGPSGGGGET(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AVGPSGGGGETPR 13 0 Q9H330-4;Q9H330 Q9H330-4 TMEM245 Transmembrane protein 245 1 AVGPS(0.001)GGGGET(0.999)PR;AVGPSGGGGET(1)PR 94.781 0.0090014 5864300.0 20966.9 22860.0 30128.0 18453.5 31062.0 15276.2 17693.699999999997 14739.4 13954.8 12771.3 True False 24516.18205484863 25129.389723523196 30846.36578107628 17419.610222054205 24975.624080432714 14475.089179786848 16017.624644705238 14352.506367685211 14158.862550112139 15086.635592444829 1.6250264616403927 1.6656722149574312 2.0446152882836053 1.1546384954626794 1.6554800390976598 0.9594643610955755 1.0617095207580036 0.9513391027269685 0.9385036486996938 1.0 13.88098349189055 -6.538503859249778 1.064115135374116 0.9486042810895068 1.733597034692148 0.6880216337335184 0.21312761865260757 0.2762263866090869 0.6683590405779699 0.10104807882196981 0.114810270645724 2.8939841002816436e-07 6.538503859249778 0.7849927536026413 AVGPSGGGGET(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 AVGPSGGGGETPR 13 0 Q9H330-4;Q9H330 Q9H330-4 TMEM245 Transmembrane protein 245 1 AVGPSGGGGET(1)PR 101.2 0.0050406999999999995 4189200.0 23844.0 20893.0 12598.0 7798.0 8495.9 10315.0 10166.0 6730.4 15253.0 3573.0 True False 23503.98018754592 20844.62354216209 11562.241069686313 8371.490933365421 7996.187865582061 9873.851495439429 10692.34573737997 7043.118954533186 13535.046518789346 4190.588289276762 5.608754323990722 4.974152100673098 2.7590973561570746 1.9976887146816862 1.9081301510920063 2.3561969856846803 2.5515142503357975 1.6806993358320894 3.2298678811812622 1.0 12.032937073323263 -5.260847385132206 2.5524457006516097 2.153192073338751 5.567785905418793 0.8409750440229223 0.5495742929810163 0.10078160020670404 1.2584132633100806 0.14036823104242566 0.46017698399075757 5.484696680838589e-06 5.260847385132206 3.414593832080042 AVGS(ph)PATATPDLVSMATTQGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVGSPATATPDLVSMATTQGVR 22 0 Q96L91-5;Q96L91-2;Q96L91;Q96L91-4;Q96L91-3 Q96L91-5 EP400 E1A-binding protein p400 1 AVGS(0.622)PAT(0.365)AT(0.007)PDLVS(0.005)MAT(0.001)T(0.001)QGVR 96.234 0.0017879 0.0 6861.3 6699.9 5842.9 8701.6 8889.4 6254.2 7741.2 6045.7 5583.2 6555.3 True False 8022.7825731478115 7365.02179390345 5982.216895321642 8214.077562967832 7147.585883091835 5926.218742110139 7007.897494565421 5887.006780948647 5664.843737623331 7743.723998273753 1.036036740841521 0.9510955963235875 0.7725245497715583 1.060739970174419 0.9230166112177022 0.7652931255596434 0.904977694985983 0.7602294170428842 0.7315399850105906 1.0 12.918811817670033 -6.632373417612388 6.536134292302421 0.8225065692200313 0.9476714796654943 0.24353733546755418 0.10251427787920765 0.30744624700941653 16.63564684203348 0.03350323525704848 0.03344280381954464 2.3314525570872307e-07 6.632373417612388 0.12516491044546296 AVGT(ph)PGGGGGGAVPGISAMSR ddPTM_PC-9_AZD4547_30min_R2 2 AVGTPGGGGGGAVPGISAMSR 21 0 P48634;P48634-2;P48634-3 P48634 PRRC2A Protein PRRC2A 1 AVGT(0.999)PGGGGGGAVPGISAMSR;AVGT(0.746)PGGGGGGAVPGIS(0.241)AMS(0.013)R 78.40100000000001 0.0042215 9728400.0 28017.0 25303.0 31688.0 38289.0 40769.0 33311.0 20500.8 42226.0 27016.0 30947.0 True False 36925.82321019796 33481.69992286641 31267.796415428595 29462.062609153018 35108.92807416499 31228.05790409794 22325.331484687984 35700.94195694932 28444.010605742882 29863.554949533678 1.2364845134009927 1.1211558697364405 1.0470219124370137 0.986555775390467 1.175644632177765 1.04569124328534 0.7475778259626319 1.1954685909725156 0.9524656610309898 1.0 14.866098293273435 -7.002949927605507 24.96351976121191 0.9768052833093711 1.103832890410283 0.23212204612572573 0.11896392532656751 195.57256247993573 1655029.5126433691 0.042321339818909155 0.03664504597308283 9.932305572794093e-08 7.002949927605507 0.12702760710091188 AVGT(ph)PGGGGGGAVPGISAMSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AVGTPGGGGGGAVPGISAMSR 21 0 P48634;P48634-2;P48634-3 P48634 PRRC2A Protein PRRC2A 1 AVGT(0.935)PGGGGGGAVPGIS(0.028)AMS(0.037)R;AVGT(1)PGGGGGGAVPGISAMSR;AVGT(0.991)PGGGGGGAVPGIS(0.004)AMS(0.006)R 93.34200000000001 0.0008191000000000001 10838300.0 51117.0 48985.0 55970.0 44746.0 58456.0 46813.7 51111.0 45881.0 42782.5 38052.6 True False 59770.09849322961 53847.907069413064 57304.537067407 42239.026688489306 47001.96642990711 44358.70716119109 46269.39606840457 44676.67236493785 43408.11312596187 44951.23515578415 1.329665320343008 1.1979182970789652 1.2748156278422815 0.9396633160825205 1.0456212441552695 0.9868184268454564 1.0293242423273168 0.9938919856174192 0.9656711984782088 1.0 15.456073137750625 -5.755644379059203 24.999999999953857 0.9974427906913701 1.2605116777114895 0.9033779840235409 0.040892924066438366 37.56189384951413 162042.2345719509 0.010551342710379415 0.017661092831368352 1.755317250624495e-06 5.755644379059203 0.26306888702011944 AVHS(ph)PIR ddPTM_PC-9_AZD4547_30min_R2 1 AVHSPIR 7 0 Q7RTP6 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 AVHS(1)PIR 76.17 0.017936 33314000.0 58612.0 46436.0 69850.0 97503.0 76205.0 68187.0 63519.0 80658.0 63785.0 73176.0 True False 77249.39679466475 61445.52889452733 68923.74336082074 75025.18975633338 65625.25114404921 63923.25611079602 69172.06794739219 68194.15943645188 67156.54488034156 70614.13051304099 1.093965134646788 0.8701591090635832 0.9760616304422516 1.0624670899612332 0.9293501267700176 0.9052473725353128 0.9795782720091345 0.9657296484569446 0.9510354994449606 1.0 16.10766928799267 -4.732428465243861 24.680001429426067 0.9605412702900645 1.0939660376330107 0.3938831205240392 0.04986549474872838 3289.3569441737595 2798125.007220891 0.012595526798644806 1.3818407485724848 1.851703872237224e-05 4.732428465243861 0.13342476734294617 AVHS(ph)PIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AVHSPIR 7 0 Q7RTP6 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 AVHS(1)PIR;AVHS(1)PIR;AVHS(1)PIR 74.173 0.019592 46614500.0 72829.0 76148.0 96642.0 103471.0 115009.0 99161.0 101332.0 112661.0 106582.0 85576.0 True False 85157.51126168227 83707.47019539995 98946.31179682593 97673.85532750825 92473.81204901465 93960.82259703605 91733.09937985128 109703.7681241963 108140.56011666622 101090.25138075672 0.8423909338293786 0.8280469090942857 0.978791826564407 0.966204495422802 0.9147648837147687 0.9294746161341745 0.9074376423730346 1.085206205601337 1.069742716430237 1.0 16.625284352362613 -1.7402578861917908 0.21607207388275468 1.0457643493223214 2.7108078607730442e-15 0.534422900802663 0.05547009684143709 39.78380348409856 0.546878859767856 0.09878882829023056 14.148328439265343 0.018186206320756033 1.7402578861917908 -1.0457643493223188 AVHS(ph)PIR ddPTM_PC-9_Lapatinib_30min_R1 2 AVHSPIR 7 0 Q7RTP6 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 AVHS(1)PIR;AVHS(1)PIR 72.87899999999999 0.021373 36169900.0 79697.0 68777.0 81836.0 66327.0 73895.0 76840.0 74128.0 65153.0 84002.0 67747.0 True False 78560.50616536003 68617.75108214642 75107.75997609532 71204.90884038588 69548.64138315963 73553.73232278864 77965.98512891028 68180.24623272027 74540.81017972484 79456.97868279666 0.9887175106290478 0.8635836929576451 0.9452632257254076 0.8961441779034388 0.8752993448292 0.9257051242336485 0.981235209561156 0.8580775076397672 0.9381279204851489 1.0 16.277886316164278 -6.992554800575698 24.92569559812206 0.935524271028497 0.9106509714238535 0.06880988904751917 0.04818640434032724 569.5142654892215 1906654.8440549392 0.016404538943439458 0.014434661609721544 1.0172909932636382e-07 6.992554800575698 -0.024873299604643462 AVIS(ph)TVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVISTVER 8 0 B4DKV7;Q8TE68-2;Q8TE68;K7EKX9;K7EN83;Q8TE68-3 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 AVIS(0.611)T(0.389)VER 80.219 0.019608 4115400.0 24463.0 27031.0 37616.0 41681.0 44025.0 40429.0 35778.0 29778.0 25020.0 23881.0 True False 28604.10273372609 29714.4590383445 38512.90809947443 39345.74870162527 35398.61728610685 38308.83206881307 32388.84882971139 28996.359052399006 25385.87016681039 28210.436258108002 1.0139546397658046 1.0533144105420995 1.365200727387028 1.394723156410488 1.2548057379273205 1.3579666658931115 1.148115843844934 1.0278592924653946 0.8998751360860008 1.0 14.783941356091239 -7.730575660025755 2.6553666408534116 0.9560673813037113 1.245143634186176 0.48751957794104517 0.12154133445328098 0.25772911070625193 3.654853179981409 0.08295003590951967 0.038151858436337276 1.85962056371957e-08 7.730575660025755 0.28907625288246463 AVIS(ph)TVER ddPTM_PC-9_Lapatinib_30min_R1 1 AVISTVER 8 0 B4DKV7;Q8TE68-2;Q8TE68;K7EKX9;K7EN83;Q8TE68-3 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 AVIS(0.5)T(0.5)VER 109.48 0.0037773000000000004 3925000.0 47109.0 26982.0 45628.0 33387.0 35702.0 38265.0 26309.0 26910.0 41828.0 27177.0 True False 46437.21702126745 26919.524836769135 41876.64196917342 35842.39135576703 33602.07855283266 36628.49515007169 27671.15128907435 28160.33683978486 37116.890171633175 31874.508238923758 1.456876343728508 0.8445471420291965 1.3137972719540028 1.1244845281094522 1.0541991205310353 1.1491469884182424 0.8681279435484294 0.8834751779918187 1.164469421564523 1.0 14.960115463740905 -6.828185029393114 1.5716778931531818 0.9769884566527075 1.163523143423148 0.1946221347334901 0.16938784710139784 0.6481093016181181 3.315083447935519 0.07349712473020431 0.06323309794153423 1.4853027003064845e-07 6.828185029393114 0.1865346867704406 AVIST(ph)VER ddPTM_PC-9_AZD4547_30min_R2 1 AVISTVER 8 0 B4DKV7;Q8TE68-2;Q8TE68;K7EKX9;K7EN83;Q8TE68-3 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 AVIS(0.104)T(0.896)VER 127.68 0.008882 4820800.0 26314.0 28544.0 35701.0 59201.0 60878.0 43747.0 31403.0 46221.0 43571.0 37312.0 True False 34681.30463479846 37770.289791657066 35227.58141338101 45553.1240963323 52426.14053077134 41011.493174343996 34197.8061643281 39078.60650291658 45874.074108040535 36005.718236888926 0.9632165759511618 1.0490080920802265 0.9783885210013478 1.2651635997546016 1.4560504024902134 1.1390272207464676 0.9497881958452765 1.0853444512843904 1.2740774619805024 1.0 15.135938425462262 -5.746373860925189 24.782403170659368 1.1724401809752847 1.0020846975143685 0.24007175286145344 0.138437070867499 350.56135558893374 576659.195455121 0.04113024554696246 0.0708704798015119 1.7931893013132286e-06 5.746373860925189 -0.17035548346091622 AVIST(ph)VER ddPTM_PC-9_Lapatinib_30min_R1 1 AVISTVER 8 0 B4DKV7;Q8TE68-2;Q8TE68;K7EKX9;K7EN83;Q8TE68-3 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 AVIS(0.134)T(0.866)VER 106.68 0.009345399999999998 4003700.0 43233.0 28201.0 46022.0 32778.0 32086.0 37474.0 26999.0 26391.0 36810.0 24421.0 True False 42616.48949203877 28135.702317164258 42238.2488100574 35188.60346420262 30198.76456350312 35871.32437616065 28396.876112878406 27617.22220508221 32664.07017351574 28642.13731106292 1.4878948812098007 0.9823185334111553 1.4746891389890455 1.2285606720630848 1.0543474544352163 1.2523969139099644 0.991437049703348 0.9642165284367643 1.140420137602628 1.0 14.805851531824162 -6.626642531855843 0.9302081371211567 1.0244193768668834 1.292418221418872 0.34976666987934624 0.1519718428611873 0.6668949645825847 1.258339032398855 0.08332304323752936 0.0885416460304918 2.3624219445752786e-07 6.626642531855843 0.2679988445519885 AVIVS(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 1 AVIVSSPK 8 0 Q14966-3;Q14966;Q14966-5 Q14966-3 ZNF638 Zinc finger protein 638 1 AVIVS(0.562)S(0.438)PK 106.6 0.0038235 5187800.0 99465.0 87422.0 80323.0 100760.0 91322.0 98289.0 101190.0 83240.0 89050.0 101390.0 True False 131092.80099947666 115679.4518696135 79257.8645378841 77531.33872648173 78643.51663246323 92142.97329218205 110195.71396899504 70377.17066490943 93757.00120082185 97840.36696071408 1.339864159055275 1.1823284750767786 0.8100732550370399 0.7924269004184433 0.8037941708051957 0.9417684760849302 1.1262806691356955 0.7193060783711904 0.9582650199837065 1.0 16.57814219440626 -5.094381264806714 3.741146911979326 0.887833555919422 1.3150374912033966 0.633181063081798 0.11421948843972832 0.14144672082396648 3.534350093132548 0.030378880727145525 0.10192050726204048 8.046717140273135e-06 5.094381264806714 0.4272039352839746 AVIVS(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVIVSSPK 8 0 Q14966-3;Q14966;Q14966-5 Q14966-3 ZNF638 Zinc finger protein 638 1 AVIVS(0.773)S(0.227)PK 101.64 0.0045228 17444000.0 105180.0 93953.0 88517.0 126510.0 98731.0 91904.0 111200.0 117660.0 102200.0 69139.0 True False 122984.89660030685 103280.0329262542 90627.58098259181 119422.05485095407 79385.3692964138 87084.3924522545 100666.3309817181 114571.54967107461 103694.48165659537 81673.35339597712 1.5058142158561665 1.2645499251821015 1.1096346264025905 1.462191153973559 0.9719861618945598 1.0662521964788567 1.2325480318367397 1.402802075673287 1.2696243921056254 1.0 16.31757784355127 -4.789513702363951 3.572311005640813 1.2019270939890587 1.5382627724876146 0.27491518011738303 0.1531238929630465 0.38706186199425324 8.330590686661795 0.039323658145548675 0.3472393103889015 1.6236271228439293e-05 4.789513702363951 0.33633567849855583 AVIVSS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 5 AVIVSSPK 8 0 Q14966-3;Q14966;Q14966-5 Q14966-3 ZNF638 Zinc finger protein 638 1 AVIVS(0.066)S(0.934)PK;AVIVS(0.245)S(0.755)PK;AVIVS(0.06)S(0.94)PK;AVIVS(0.341)S(0.659)PK;AVIVS(0.199)S(0.801)PK 119.68 0.0034489000000000004 323237900.0 1218341.0 1042198.0 1047133.0 1249850.0 1218370.0 1132860.0 1180750.0 1046521.0 1065396.0 1130418.0 True False 1605748.094932922 1379068.1222073096 1033247.332235451 961716.3924900085 1049220.356097043 1062022.085114118 1285834.4625841607 884805.2261101807 1121710.6575109577 1090842.4098924615 1.4720257301796886 1.2642230533952765 0.9472012848650719 0.8816272486002973 0.9618441184373079 0.9735797540350629 1.178753641152366 0.811121036445042 1.0282976233217218 1.0 20.057011265038497 -5.05558477941529 2.762563363728053 0.9693775707784335 1.4656643021176297 0.7622490153235595 0.09162448598943038 0.13496716255035682 1.8843868185688264 0.02433563796930191 0.11337841169271701 8.798633352003531e-06 5.05558477941529 0.4962867313391962 AVIVSS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AVIVSSPK 8 0 Q14966-3;Q14966;Q14966-5 Q14966-3 ZNF638 Zinc finger protein 638 1 AVIVS(0.04)S(0.96)PK;AVIVS(0.016)S(0.984)PK;AVIVS(0.035)S(0.965)PK;AVIVS(0.026)S(0.974)PK 131.62 0.003752 210285000.0 478900.0 461280.0 383085.0 533930.0 482670.0 374113.0 522930.0 498960.0 380162.0 352893.0 True False 559968.3112938488 507072.8299066826 392219.19925795286 504015.6331244145 388094.27837558626 354493.85569170304 473394.28471465677 485862.8286918191 385721.1500541559 416869.70740054944 1.343269374945978 1.2163820515254218 0.94086759554608 1.2090483529428797 0.9309726072340528 0.8503708698389242 1.1355929114316663 1.1655028419346805 0.9252798733191125 1.0 18.669237014319158 -5.049757530815787 3.7859576815627167 1.027699399750758 1.327239924378975 0.47952458939658893 0.11151235892460822 0.1913410739767729 5.508679040482378 0.029476098033190762 0.1065235917879528 8.917486677465705e-06 5.049757530815787 0.299540524628217 AVIVSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 6 AVIVSSPK 8 0 Q14966-3;Q14966;Q14966-5 Q14966-3 ZNF638 Zinc finger protein 638 1 AVIVS(0.198)S(0.802)PK;AVIVS(0.159)S(0.841)PK;AVIVS(0.004)S(0.996)PK;AVIVS(0.001)S(0.999)PK;AVIVS(0.206)S(0.794)PK;AVIVS(0.366)S(0.634)PK 146.69 0.0012055999999999998 382752600.0 1378490.0 1182410.0 1007460.0 1088650.0 1070920.0 966580.0 975530.0 928120.0 891940.0 832790.0 True False 1358832.4798158952 1179672.2022920516 924630.5277080607 1168712.952629941 1007930.5911097289 925241.6266080305 1026038.1700950518 971243.84346864 791480.3246554103 976736.641877078 1.3911963794094089 1.2077689642368439 0.9466528520227515 1.1965486933959248 1.0319369089836774 0.9472785057289496 1.0504757639922537 0.9943763772413801 0.8103313531213031 1.0 19.897610094280644 -1.5228787452804946 0.4970063439680179 0.9658218790216815 14.013074650062382 0.6695490477095607 0.0903061755333141 65.34622497272822 0.7001014837400145 0.05060688578495562 888.8051029855078 0.029999999999989153 1.5228787452804946 13.0472527710407 AVLFCLS(ph)EDKK ddPTM_PC-9_AZD4547_30min_R2 2 AVLFCLSEDKK 11 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 1 AVLFCLS(1)EDKK;AVLFCLS(1)EDKK 65.563 0.020346 10321200.0 38144.0 43745.0 41486.0 60152.0 84849.0 71385.0 46558.0 44866.0 58413.0 44443.0 True False 50272.99855551239 57884.715769900424 40935.868533529145 46284.88573913587 73069.18095035026 66921.2846652466 50701.57180520291 37932.990618114185 61500.59192749702 42887.06409739637 1.1722182344154544 1.3497010576066584 0.9545038671932389 1.0792271915378273 1.7037580559119274 1.560407224734913 1.182211300126766 0.88448559994614 1.4340126381192566 1.0 15.388254936905495 -9.155010791643912 0.6723485271003492 1.000330059312723 1.2698786405022133 0.07840302274218447 0.24775702400951893 6.535101020935739 4.462656132668421 0.3585950678021216 0.10250230653531452 6.998246060696428e-10 9.155010791643912 0.26954858118949043 AVLFCLS(ph)EDKK ddPTM_PC-9_Lapatinib_30min_R1 2 AVLFCLSEDKK 11 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 1 AVLFCLS(1)EDKK;AVLFCLS(1)EDKK 65.295 0.020652 6849600.0 24016.0 28107.0 35232.0 26923.3 37677.0 30721.0 32894.0 27948.0 29999.0 34266.0 True False 23673.527436005003 28041.91996838892 32335.360959452944 28903.32929549593 35460.91293583205 29407.13444414875 34597.09036842187 29246.566109190153 26620.196716525366 40188.83244342502 0.5890573573972548 0.6977540342298907 0.804585726768061 0.719188081320451 0.8823573808906094 0.7317240301903775 0.8608632862655365 0.7277286830952701 0.6623779567122132 1.0 15.294507044715496 AVLFCLSEDKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AVLFCLSEDKK 11 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 0 ; 108.7 0.0013624000000000002 25862000.0 58590.0 44786.0 57584.0 69479.0 81475.0 83711.0 77422.0 83015.0 60740.0 66712.0 False True 68508.12979475166 49232.058099637325 58957.020948536105 65586.31688395712 65510.5586231813 79321.04779520679 70088.02767326037 80835.94421166329 61628.207591209575 78806.3575080985 0.8693223739938931 0.624721908947232 0.7481251870127028 0.8322465211923691 0.831285199502453 1.0065310757073804 0.8893702220161337 1.025754098625307 0.7820207599986635 1.0 16.266024399782296 -6.237706389782962 1.6085441760875387 0.9373061013866545 0.737690121350988 0.4535931155826086 0.0890210498151008 0.31908978620232514 1.6393884214677727 0.030549416593703114 0.04211516291435552 5.784870086121302e-07 6.237706389782962 -0.1996159800356665 AVLFCLSEDKK ddPTM_PC-9_Lapatinib_30min_R1 2 AVLFCLSEDKK 11 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 0 ; 73.9 0.014924000000000002 45136000.0 221663.0 124015.0 134921.0 120088.0 113193.0 102822.0 113489.0 102852.0 105644.0 124192.0 False True 218502.04497198443 123727.85088695899 123828.31619012106 128919.67212182422 106535.21028600026 98424.54274978887 119364.90511405826 107630.87939968609 93745.26023936161 145658.42172456186 1.5000989464596073 0.849438360117115 0.8501280923136648 0.8850821709822561 0.7314043982122567 0.6757216066497574 0.8194850919075294 0.7389265799077148 0.6435965674311139 1.0 17.15222959252344 AVLPVTCHRDS(ph)FSR ddPTM_PC-9_Lapatinib_30min_R1 1 AVLPVTCHRDSFSR 14 1 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 AVLPVTCHRDS(0.935)FS(0.065)R 64.53399999999999 0.019353 6950200.0 18211.0 23087.0 23544.0 22439.0 19712.0 14310.0 13710.0 17208.0 19848.0 18766.0 True False 17951.30780051161 23033.543469961045 21608.30320246821 24089.238914309655 18552.578915283102 13697.99465823928 14419.836716454794 18007.546500892528 17612.50923129424 22009.678095876785 0.8156097386937498 1.0465188709087057 0.9817637090528931 1.0944839269967537 0.8429282261406029 0.6223623352676573 0.6551589102593989 0.8181649191982502 0.8002165753888834 1.0 14.42585042469358 -6.494560681002385 8.29158350407102 0.7569598960000424 0.9867005304204104 0.40045524554469747 0.11733178303837823 0.24709347629963196 65.57349685130069 0.03642883939484426 0.040286928015609354 3.2021326512409934e-07 6.494560681002385 0.22974063442036796 AVLRVS(ph)STQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVLRVSSTQGK 11 1 A0A286YF57;Q8NH92 A0A286YF57 OR1S1 Olfactory receptor 1S1 1 AVLRVS(0.333)S(0.333)T(0.333)QGK 52.79 0.041218 1945800.0 11364.0 10364.0 11856.0 13924.0 15273.0 13864.0 13438.0 13302.0 12296.0 11676.0 True False 13287.700750769049 11392.869426710156 12138.692004130387 13143.88342221708 12280.36528814786 13136.947433822868 12165.055357305091 12952.83659463401 12475.805738253419 13792.766372834862 0.9633818475269362 0.8260032192779433 0.8800766775864335 0.9529548363919388 0.8903482416938703 0.9524519649442014 0.8819880674020855 0.9391036028961449 0.9045180206071478 1.0 13.751624222341066 -14.522878745198849 0.1863710400958645 1.385636115803355 0.8914164811162225 0.30439632542294315 0.04066328578448957 161.2735623979487 1.5645420956033413 23.043887670573913 0.1123282369790989 3.0000000005629046e-15 14.522878745198849 -0.4942196346871325 AVLS(ph)DSPQLSEGK ddPTM_PC-9_Lapatinib_30min_R1 1 AVLSDSPQLSEGK 13 0 Q5VY60;Q7Z4H7-3;Q7Z4H7;Q5SYF9;Q7Z4H7-2 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 AVLS(0.933)DS(0.067)PQLSEGK 191.01 1.3482e-05 8826700.0 60785.0 54840.0 61424.0 58389.0 63585.0 52468.0 44858.0 46301.0 59768.0 43290.0 True False 59918.19475339618 54713.02134935955 56373.95582349673 62683.12183999409 59845.05531291982 50224.06594888176 47180.527748120316 48452.31349011065 53036.29845505809 50772.618819700874 1.180128111298971 1.0776088100488075 1.1103220029616125 1.2345851621833555 1.1786875820890028 0.9891958917311892 0.929251412373735 0.9543000659897044 1.0445846538543893 1.0 15.63176305483771 -6.7812055453326945 9.728460920873111 0.9770252568792777 1.1537100513359655 0.75942478196258 0.04855177211889764 0.14642928075326367 67.22388936711876 0.01819227301725937 0.016353473855061862 1.6549864967738357e-07 6.7812055453326945 0.17668479445668783 AVLS(ph)PGSVFSPGR ddPTM_PC-9_AZD4547_30min_R2 1 AVLSPGSVFSPGR 13 0 P27987-2;P27987 P27987-2 ITPKB Inositol-trisphosphate 3-kinase B 1 AVLS(0.933)PGS(0.067)VFSPGR 131.32 0.00052302 0.0 30438.0 27688.0 33747.0 62945.0 60410.0 50925.0 40364.0 66975.0 50729.0 48168.0 True False 40116.65085026967 36637.60453164941 33299.49273010191 48434.0027405557 52023.1142525033 47740.65169962435 43956.31780457086 56625.55268239188 53410.43137469388 46481.65298119814 0.8630642044183945 0.7882164721308287 0.716400785995532 1.04200258885258 1.119218248833506 1.0270859282679874 0.945670280322243 1.2182344871706037 1.1490648018971794 1.0 15.504373754345538 -5.827571938515369 6.270362262613106 1.077695526755324 0.7897530024964278 0.7236399059191334 0.08004183136427723 0.10653951167049266 7.61642360058719 0.023792632634179606 0.03590453689821239 1.4874009738030454e-06 5.827571938515369 -0.2879425242588963 AVLS(ph)PGSVFSPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVLSPGSVFSPGR 13 0 P27987-2;P27987 P27987-2 ITPKB Inositol-trisphosphate 3-kinase B 1 AVLS(0.5)PGS(0.5)VFSPGR 135.02 4.9111000000000005e-05 2428900.0 5475.5 3737.8 8279.9 9107.5 10842.0 12024.0 13793.0 13090.0 10406.0 11659.0 True False 6402.3940039454355 4108.864081740372 8477.324217695612 8597.236301913385 8717.587929948219 11393.440272957736 12486.427187327658 12746.401370001444 10558.16806378213 13772.684407406789 0.46486173752026894 0.29833429418673624 0.6155172054284934 0.6242237204890785 0.632962149721517 0.8272490631405507 0.9066080959941697 0.9254841680062442 0.7666020473179558 1.0 13.749522159342646 -6.0416696042789155 0.5776613603713726 0.9301357254582661 0.31121031924543285 0.8352908173010885 0.0849149481225993 0.4529045381935839 0.2836423544642247 0.05881706748890061 0.15842793443801576 9.085114303667626e-07 6.0416696042789155 -0.6189254062128332 down AVLS(ph)PGSVFSPGR ddPTM_PC-9_Lapatinib_30min_R1 2 AVLSPGSVFSPGR 13 0 P27987-2;P27987 P27987-2 ITPKB Inositol-trisphosphate 3-kinase B 1 AVLS(0.936)PGS(0.039)VFS(0.024)PGR;AVLS(0.496)PGS(0.496)VFS(0.007)PGR 103.97 0.0013905999999999999 6292700.0 20670.6 23541.5 24494.3 20007.1 29079.0 25972.7 27677.0 23614.0 31465.0 24241.8 True False 20375.83345347621 23486.991103135453 22480.47320473229 21478.488875729083 27368.630391513645 24861.90816632085 29109.979635398922 24711.19264714528 27921.080358860978 28431.96282983192 0.716652366754542 0.826077019152965 0.7906760901201273 0.7554346143556793 0.9626008079469426 0.8744351670379497 1.023846992542337 0.8691342484880199 0.9820314033882 1.0 14.795226079940742 -6.262375351725256 24.999703244068847 0.9451781174405172 0.7773766652677055 0.7313303026404785 0.05325474402316989 44.54008649600154 1189661.1989286458 0.015214144640017527 0.018265152011815486 5.465433925732594e-07 6.262375351725256 -0.16780145217281162 AVLSDS(ph)PQLSEGK ddPTM_PC-9_AZD4547_30min_R2 4 AVLSDSPQLSEGK 13 0 Q5VY60;Q7Z4H7-3;Q7Z4H7;Q5SYF9;Q7Z4H7-2 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 AVLSDS(1)PQLSEGK;AVLSDS(0.959)PQLS(0.04)EGK;AVLS(0.001)DS(0.999)PQLSEGK;AVLS(0.089)DS(0.882)PQLS(0.029)EGK 194.01 1.3537e-06 46569300.0 263272.0 243316.0 305361.0 395252.0 354944.0 328973.0 283177.0 333947.0 262025.0 331968.0 True False 346987.0196022146 321963.1386962876 301311.7136206671 304132.7579825267 305666.1523794158 308402.26630496804 308379.204413461 282343.1644886408 275875.1065653603 320345.9013631959 1.0831635994893347 1.005048409629122 0.9405823902802223 0.9493886348735038 0.9541753182378421 0.9627164417980593 0.9626444512047384 0.8813696797341912 0.8611788238632204 1.0 18.289271006625206 -1.5228787785830442 0.6672606089392656 0.9298879695943799 16.533820841941083 0.5815564142188991 0.03842492478278983 175.29170777067714 1.0592106258089975 0.01650684094427158 4055.534863587359 0.02999999769953061 1.5228787785830442 15.603932872346702 AVLSDS(ph)PQLSEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AVLSDSPQLSEGK 13 0 Q5VY60;Q7Z4H7-3;Q7Z4H7;Q5SYF9;Q7Z4H7-2 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 AVLS(0.006)DS(0.992)PQLS(0.002)EGK;AVLS(0.079)DS(0.918)PQLS(0.003)EGK;AVLS(0.002)DS(0.951)PQLS(0.047)EGK 189.33 3.5902e-08 14372600.0 144462.0 146954.0 140213.0 152181.0 176075.0 164366.0 161176.0 133726.0 157494.0 116679.0 True False 168916.5633454416 161542.62193484837 143556.2096807639 143654.79194745864 141574.3677149631 155746.35761019375 145908.2424668106 130215.83419440921 159797.05180062485 137831.97906954435 1.225525197314429 1.172025701331188 1.0415304971303598 1.0422457322112189 1.0271518168039253 1.1299725844581434 1.058594989724346 0.9447432669359529 1.15936122284073 1.0 17.07255112802695 -5.13844386819841 3.251951964917779 1.0501677815582857 1.2179176212109135 0.5239110569387728 0.05743636010880133 0.19145270542672238 3.6898102988481214 0.014568005258207208 0.05040437147220818 7.270363613188549e-06 5.13844386819841 0.1677498396526278 AVLSDS(ph)PQLSEGK ddPTM_PC-9_Lapatinib_30min_R1 3 AVLSDSPQLSEGK 13 0 Q5VY60;Q7Z4H7-3;Q7Z4H7;Q5SYF9;Q7Z4H7-2 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 AVLS(0.001)DS(0.967)PQLS(0.032)EGK;AVLS(0.003)DS(0.996)PQLS(0.001)EGK;AVLS(0.063)DS(0.935)PQLS(0.003)EGK 174.24 5.3462e-05 33020000.0 251493.0 225162.0 251840.0 226941.0 243134.0 254041.0 206648.0 199136.0 235672.0 179169.0 True False 247906.6637018328 224640.65122291225 231134.6873305125 243630.99819298374 228833.33613983574 243176.25862849533 217347.22230357045 208388.58554170906 209128.13762381955 210138.1229223139 1.1797319793966257 1.0690142659452602 1.09991792120443 1.1593850501988725 1.0889663091948019 1.1572210470272228 1.0343064803330413 0.99167434563384 0.9951937074318127 1.0 17.68097839161998 -7.436428088087896 4.129833279163262 0.9971758859304373 1.121520747064871 0.7713634392465855 0.03251144383786353 0.10804723501284517 3.335743538816238 0.01421060030373981 0.009065110867704326 3.6607655170213314e-08 7.436428088087896 0.12434486113443366 AVLSPGS(ph)VFSPGR ddPTM_PC-9_AZD4547_30min_R2 1 AVLSPGSVFSPGR 13 0 P27987-2;P27987 P27987-2 ITPKB Inositol-trisphosphate 3-kinase B 1 AVLS(0.312)PGS(0.682)VFS(0.006)PGR 99.73200000000001 0.0083212 0.0 15674.0 18536.0 24237.0 37215.0 28242.0 21341.0 18984.0 31338.0 17105.0 23349.0 True False 20658.005960546907 24527.399508763843 23915.601543825534 28635.656716018435 24321.085792405214 20006.543896351173 20673.539223118943 26495.432175599813 18009.13537945039 22531.558616882485 0.9168476230076796 1.0885797971555289 1.0614268613404316 1.2709132644983672 1.0794231418230371 0.8879343074544623 0.9175370232767048 1.1759254042792793 0.7992849356615956 1.0 14.459659494768225 -6.651369739792006 7.909111887614134 0.9650413966143465 1.0942442071678176 0.2147274570605605 0.12050281840696891 0.391787499673223 25.946816016804572 0.039877485628869315 0.039825909957001644 2.2316714639663417e-07 6.651369739792006 0.12920281055347105 AVLSPGS(ph)VFSPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVLSPGSVFSPGR 13 0 P27987-2;P27987 P27987-2 ITPKB Inositol-trisphosphate 3-kinase B 1 AVLS(0.415)PGS(0.579)VFS(0.007)PGR 104.17 0.0013685000000000001 2255800.0 6080.4 6183.3 5807.4 8261.9 12254.0 16734.0 17162.0 13306.0 14751.0 10588.0 True False 7109.69162662585 6797.137159993919 5945.870440687146 7799.012528441202 9852.916666075036 15856.439581476614 15536.291117879899 12956.731598872359 14966.705468849716 12507.520585438124 0.5684333340137218 0.5434440114300099 0.47538362220323854 0.623545847889405 0.7877593803480356 1.2677524272826277 1.242155950234295 1.03591527276455 1.1966164969798008 1.0 13.610508206334197 -6.528643421688022 2.810900423396896 1.1559997468247247 0.5472139481871131 0.9081386550029422 0.08931804664508804 0.0743364121991185 1.1924935291244891 0.031489981773749294 0.033485450818946515 2.960442145633959e-07 6.528643421688022 -0.6087857986376116 AVLVDLEPGTMDS(ph)VR ddPTM_PC-9_AZD4547_30min_R2 1 AVLVDLEPGTMDSVR 15 0 P04350;M0R0X0;M0QY85;M0QY37;M0QX14;M0QZL7;M0R278;A0A075B724;P68371;Q3ZCM7 P04350;P68371 TUBB4A;TUBB8;TUBB4B Tubulin beta-4A chain;Tubulin beta-4B chain;Tubulin beta-8 chain 1 AVLVDLEPGT(0.008)MDS(0.992)VR 67.095 0.026883999999999998 2418900.0 7200.7 8288.4 9106.1 16585.0 11938.0 14187.0 8876.1 9744.1 13828.0 11648.0 True False 9490.372816135648 10967.463211504004 8985.347164179953 12761.58448569571 10280.61476487973 13299.884647276796 9666.055704715873 8238.373242142521 14558.9198495785 11240.20706537527 0.8443236642294719 0.97573497958846 0.7993933841182279 1.1353513695496718 0.9146285922568542 1.1832419607505478 0.8599535265227926 0.7329378537447317 1.295253705283269 1.0 13.456380992460462 -5.746168383735762 24.95446750902729 1.002285984127514 0.8834091490124157 0.14124123074972184 0.15933862897563492 563.4901888833277 920796.8757459583 0.042334904222927176 0.07297125529274097 1.7940379113951744e-06 5.746168383735762 -0.11887683511509828 AVLVDLEPGTMDSVR ddPTM_PC-9_Lapatinib_30min_R1 1 AVLVDLEPGTMDSVR 15 0 P04350;M0R0X0;M0QY85;M0QY37;M0QX14;M0QZL7;M0R278;A0A075B724;P68371;Q3ZCM7 P04350;P68371 TUBB4A;TUBB8;TUBB4B Tubulin beta-4A chain;Tubulin beta-4B chain;Tubulin beta-8 chain 0 97.163 0.033427 8597700.0 25934.0 27395.0 37080.0 27552.0 27631.0 27150.0 24673.0 25864.0 31569.0 25456.0 False True 25564.176404286864 27331.56856064378 34031.42553293921 29578.265990777647 26005.798904636133 25988.8577897412 25950.447214083822 27065.73586117411 28013.36678369245 29856.03568201211 0.8562481863487644 0.915445334127555 1.1398507790986705 0.9906963639046755 0.8710399190842442 0.8704724922806535 0.8691859659626092 0.9065415164103947 0.9382815281323554 1.0 14.86573499506904 -6.251568146103257 23.970316411112552 0.9006382123496646 0.9830013013907705 0.14268908053741514 0.07706558424074368 684.1677553869763 1661361.9214805202 0.024054849264007902 0.03064119678213823 5.603144902857429e-07 6.251568146103257 0.0823630890411059 AVNELS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 AVNELSR 7 0 G3V3A5 G3V3A5 TTC6 1 AVNELS(1)R 74.165 0.034581 4851000.0 21953.0 17015.0 14613.0 15905.0 19852.0 25155.0 15033.0 20899.0 18329.0 16707.0 True False 21639.94619431285 16975.602812898487 13411.57554781125 17074.706757524626 18684.344390533683 24079.179289169035 15811.335182966088 21870.043835550492 16264.595007073358 19594.782689321826 1.1043728597258462 0.8663327928688558 0.6844462508441028 0.8713904628720116 0.9535366983536752 1.2288566640900274 0.8069155669474443 1.1161156611075136 0.8300472255778956 1.0 14.25818195275616 -6.3596845507038795 4.6164124514352185 1.0006425986984195 0.8668145077636622 0.11021227701646863 0.14918082650787212 0.45237031069974953 16.055702581115934 0.04677624905339348 0.05344045309218389 4.3683301018851585e-07 6.3596845507038795 -0.13382809093475734 AVNTQALS(ph)GAGILR ddPTM_PC-9_AZD4547_30min_R2 2 AVNTQALSGAGILR 14 0 O60749;O60749-2 O60749 SNX2 Sorting nexin-2 1 AVNT(0.003)QALS(0.997)GAGILR;AVNT(0.008)QALS(0.992)GAGILR 105.19 0.00099476 8385000.0 20287.2 21432.7 29146.3 36888.0 31069.0 29500.0 17248.8 24119.2 21388.6 26579.0 True False 26738.10760002596 28360.401135707973 28759.801018145907 28384.041513918797 26755.605639977253 27655.360336552152 18783.909784646767 20392.13184407835 22519.15773030767 25648.47730001796 1.0424832354475577 1.105734301649483 1.1213063715921165 1.1066560085381334 1.0431654607409586 1.0782456990744158 0.7323596471215706 0.7950620851891302 0.877991994101416 1.0 14.646585557938458 -7.244830831898432 24.26914264904231 0.8342752821752436 1.0849834545876953 0.730181062908962 0.06864428008731677 257.022725580821 375573.37825544825 0.02554319845730549 0.019723332895242335 5.690745558451163e-08 7.244830831898432 0.2507081724124517 AVNTQALS(ph)GAGILR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVNTQALSGAGILR 14 0 O60749;O60749-2 O60749 SNX2 Sorting nexin-2 1 AVNT(0.006)QALS(0.994)GAGILR 86.777 0.0063685 2451500.0 14930.0 14484.0 15637.0 13154.0 13938.0 10497.0 10429.0 10054.0 12780.0 9662.9 True False 17457.354119058597 15921.875798578738 16009.845383652737 12417.024025843397 11206.94895477018 9946.51884108761 9441.089620578563 9790.093153093547 12966.883322615378 11414.707278525686 1.5293737888400214 1.3948562508065643 1.4025629385846639 1.08780923792968 0.9817990668804658 0.8713774780541105 0.8270987060999752 0.857673606007532 1.1359803634220018 1.0 13.478606242770917 -5.850819559776115 1.7774397031298894 0.9241673844513428 1.471681826773129 0.8628188782311508 0.08865490725928946 0.11943994022877842 0.7698496140272769 0.028862219353290825 0.05467740571509714 1.409874449934364e-06 5.850819559776115 0.5475144423217863 AVPAPSPGPTHNS(ph)PELGRPPAAGVLAPDMSDKDK ddPTM_PC-9_Lapatinib_30min_R1 2 AVPAPSPGPTHNSPELGRPPAAGVLAPDMSDKDK 34 2 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 AVPAPS(0.003)PGPT(0.105)HNS(0.889)PELGRPPAAGVLAPDMS(0.003)DKDK;AVPAPS(0.028)PGPT(0.208)HNS(0.764)PELGRPPAAGVLAPDMSDKDK 61.538000000000004 9.661899999999999e-05 20052100.0 65056.0 53106.0 60349.0 53977.0 57453.0 55406.0 45080.0 55527.0 58574.0 37779.0 True False 64128.2895101907 52983.03631982288 55387.33817387677 57946.64864199355 54073.72749694399 53036.414537694305 47414.02182186594 58106.987131279595 51976.77930843554 44309.04981264676 1.4472955249852164 1.1957610588322836 1.2500231534657742 1.307783599219822 1.2203765985861919 1.1969657386459363 1.0700753462858723 1.3114022389777045 1.1730510929078928 1.0 15.435313768768236 -2.1961955689325556 0.026056642420705836 1.4931970238539694e-10 2.8357038481646857 0.5338766987854446 0.08157164036862863 1408.9355886454412 3.1692505700750204 121.61086940692948 241.9003327558317 0.006365088274563565 2.1961955689325556 2.835703848015366 AVPDSER ddPTM_PC-9_AZD4547_30min_R2 1 AVPDSER 7 0 O00743-2;O00743;O00743-3 O00743-2 PPP6C Serine/threonine-protein phosphatase 6 catalytic subunit;Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed 0 88.64299999999999 0.028713 0.0 13369.0 11703.0 15756.0 23164.0 15806.0 16185.0 11698.0 14690.0 15159.0 18032.0 False True 17620.06390752529 15485.765885361649 15547.065145212478 17823.89768023245 13611.609731419754 15172.949391427013 12739.099337971216 12419.998042617954 15960.273792288128 17400.705168513643 1.0126063131860066 0.8899504781784906 0.8934732813785442 1.0243204230874832 0.7822447193720511 0.8719732473188658 0.7321024759974932 0.7137640642915888 0.917219942394521 1.0 14.086858152433987 -6.27337766982823 24.91216151648944 0.8184876544334557 0.9460339483035697 0.27936564548653875 0.09042517602930074 861.498026250289 1797722.7925344554 0.027289644166876393 0.031188890872080943 5.328713000447503e-07 6.27337766982823 0.12754629387011396 AVPEGFVIPR ddPTM_PC-9_Lapatinib_30min_R1 2 AVPEGFVIPR 10 0 P43490;A0A0C4DFS8 P43490 NAMPT Nicotinamide phosphoribosyltransferase 0 ; 104.06 0.012254000000000001 12685500.0 32605.0 37578.0 30981.0 35240.0 36258.0 34350.0 33570.0 26624.0 38250.0 29392.0 False True 32140.046720975297 37490.99044978545 28433.861770118405 37831.66715719384 34125.37572597069 32880.93057376095 35308.09034072849 27861.048235690523 33941.882209643496 34472.3680376218 0.9323422947300545 1.087566436076258 0.8248305349689581 1.0974490384851376 0.9899341898626628 0.9538344026112734 1.0242432519342626 0.8082139354419765 0.9846112739513759 1.0 15.073152785849343 AVPETEDVQASVSDTAQQPSEEQS(ph)KSLEKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AVPETEDVQASVSDTAQQPSEEQSKSLEKPK 31 2 H0YME2;H0YK21;H0YK54;Q6FIF0-2;Q6FIF0 H0YME2 ZFAND6 AN1-type zinc finger protein 6 1 AVPETEDVQASVSDT(0.001)AQQPS(0.032)EEQS(0.484)KS(0.484)LEKPK;AVPETEDVQASVS(0.002)DT(0.014)AQQPS(0.132)EEQS(0.426)KS(0.426)LEKPK 77.646 3.6293e-07 12833500.0 24824.1 27716.0 28177.0 45369.0 45858.0 40559.0 46636.0 38014.0 38214.0 31952.0 True False 29026.32983167599 30467.461311337192 28848.846541867562 42827.12201828257 36872.45409440745 38432.01463996117 42218.300464598935 37016.17277916235 38772.807456214716 37744.64466810715 0.7690184948595419 0.8071995796818585 0.7643162836884192 1.134654264064908 0.9768923358169359 1.018211059552902 1.1185242525351382 0.9806999934599906 1.0272399646929602 1.0 15.20398434428277 -5.750046993410644 24.99999688138632 1.0359580520943727 0.7828801733623268 0.8419685024646738 0.05090434106146497 77.94907105698124 171053.6234147183 0.013426679365715292 0.022995718032957746 1.7780869993661217e-06 5.750046993410644 -0.2530778787320459 AVPETEDVQASVSDTAQQPSEEQS(ph)KSLEKPK ddPTM_PC-9_Lapatinib_30min_R1 1 AVPETEDVQASVSDTAQQPSEEQSKSLEKPK 31 2 H0YME2;H0YK21;H0YK54;Q6FIF0-2;Q6FIF0 H0YME2 ZFAND6 AN1-type zinc finger protein 6 1 AVPETEDVQASVS(0.002)DT(0.008)AQQPS(0.152)EEQS(0.419)KS(0.419)LEKPK 73.072 4.5946e-06 7387400.0 33839.0 31278.0 29170.0 30769.0 27311.0 29310.0 24120.0 23857.0 23211.0 21294.0 True False 33356.44965468743 31205.57771271459 26771.75519945625 33031.85490237505 25704.620675491922 28056.479624947122 25368.815579933613 24965.48331426039 20596.732757334255 24974.639527528532 1.3356128571113095 1.2494906154027947 1.071957622048832 1.3226158826422851 1.0292288962632978 1.1233987819532532 1.0157830527231673 0.9996333795625738 0.8247059075519914 1.0 14.608176234520094 -6.6729001338847915 0.5684532641571017 0.918116636963747 1.28615378620709 0.6538057439993832 0.09051114630729401 0.5716401512704317 0.4013271083867233 0.07321522544806358 0.09467538981167813 2.123732758688542e-07 6.6729001338847915 0.36803714924334296 AVPETEDVQASVSDTAQQPSEEQSKS(ph)LEKPK ddPTM_PC-9_AZD4547_30min_R2 1 AVPETEDVQASVSDTAQQPSEEQSKSLEKPK 31 2 H0YME2;H0YK21;H0YK54;Q6FIF0-2;Q6FIF0 H0YME2 ZFAND6 AN1-type zinc finger protein 6 1 AVPETEDVQAS(0.002)VS(0.007)DT(0.006)AQQPS(0.062)EEQS(0.205)KS(0.718)LEKPK 57.058 0.00046199 7129700.0 4673.9 6623.1 10140.0 10967.0 11811.0 11330.0 12853.0 11303.0 9304.1 13212.0 True False 6160.102976840641 8763.887553220426 10005.5369746417 8438.727588460953 10171.246522700154 10621.533308919868 13996.89210043974 9556.381067100801 9795.895731303388 12749.451901419823 0.48316610192118375 0.6873932794118348 0.7847817343055703 0.6618894407155799 0.7977791203375142 0.8330972492815175 1.09784265305405 0.7495523055415872 0.7683385769871788 1.0 13.63814760654729 -4.078845856328683 0.4067985423746508 0.8998766188556799 1.7293783764718103e-14 0.5511499660872823 0.1088301158157436 8.404706699873355 0.7061765231022604 0.08771864622666521 4.119504509833216 8.339771346994248e-05 4.078845856328683 -0.8998766188556626 AVPETEDVQASVSDTAQQPSEEQSKS(ph)LEKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVPETEDVQASVSDTAQQPSEEQSKSLEKPK 31 2 H0YME2;H0YK21;H0YK54;Q6FIF0-2;Q6FIF0 H0YME2 ZFAND6 AN1-type zinc finger protein 6 1 AVPETEDVQAS(0.004)VS(0.004)DT(0.003)AQQPS(0.189)EEQS(0.189)KS(0.611)LEKPK 49.94 0.0034248000000000004 6861200.0 8135.4 7910.6 9960.0 16450.0 15887.0 14914.0 17019.0 14013.0 13664.0 14470.0 True False 9512.562538525739 8695.912088665897 10197.484173510344 15528.359831619575 12774.05639578374 14131.883585403499 15406.837113110236 13645.173598000789 13863.810150251684 17093.296455543023 0.5565083694222714 0.5087323039931236 0.5965779742972572 0.9084473478832125 0.7473138039234886 0.8267500433376503 0.9013379691378429 0.7982763086973739 0.8110670862293458 1.0 14.061143028257884 -5.665950721892559 4.999491864720685 0.8435334140355845 0.5381970924867451 0.8042196647116848 0.06844020867982431 0.08354560404843608 3.4246251146984794 0.017984260295104266 0.031644571168198465 2.157989255905122e-06 5.665950721892559 -0.3053363215488394 AVPETEDVQASVSDTAQQPSEEQSKS(ph)LEKPK ddPTM_PC-9_Lapatinib_30min_R1 1 AVPETEDVQASVSDTAQQPSEEQSKSLEKPK 31 2 H0YME2;H0YK21;H0YK54;Q6FIF0-2;Q6FIF0 H0YME2 ZFAND6 AN1-type zinc finger protein 6 1 AVPETEDVQASVSDT(0.001)AQQPS(0.048)EEQS(0.187)KS(0.764)LEKPK 87.098 1.9668e-09 14749000.0 51996.0 45258.0 46217.0 47539.0 47392.0 41635.0 38516.0 42648.0 37460.0 32898.0 True False 51254.527505101425 45153.20788164326 42417.2166627792 51035.17664545511 44604.495736256904 39854.368105925365 40510.17001976461 44629.58177417852 33240.86032871232 38584.37546617042 1.3283752007348104 1.1702459178387425 1.0993366135981466 1.3226902348128238 1.1560248208595403 1.0329146869532315 1.0499112537219286 1.1566749813874362 0.8615109076433508 1.0 15.235729133755948 -7.014420734539706 0.6176107438780511 0.9719261852774458 1.2401099524052195 0.5336561482734306 0.0925720636571991 0.6961146689710833 0.5601114964471011 0.07982267124743309 0.07008602096134907 9.673402650995163e-08 7.014420734539706 0.2681837671277737 AVPIAVADEGES(ph)ESEDDDLKPR ddPTM_PC-9_AZD4547_30min_R2 2 AVPIAVADEGESESEDDDLKPR 22 1 Q9Y2K6 Q9Y2K6 USP20 Ubiquitin carboxyl-terminal hydrolase 20 1 AVPIAVADEGES(0.968)ES(0.032)EDDDLKPR;AVPIAVADEGES(0.974)ES(0.026)EDDDLKPR 103.94 2.1923000000000003e-05 9571400.0 45213.5 46617.3 52066.0 63147.0 53224.0 56376.0 53504.0 55433.0 49602.0 50346.0 True False 59590.452500777516 61685.43057401255 51375.57082067995 48589.4347614246 45834.766313114305 52850.79980791407 58265.75234901795 46867.103573617496 52223.86045550998 48583.40186412975 1.2265598993547326 1.269681171082347 1.0574716641777966 1.0001241760984898 0.9434243909328871 1.0878365404653771 1.1992933823770975 0.9646731553440386 1.0749321466117436 1.0 15.56817589218027 -5.286260061190108 6.998678573799113 1.0417123454602846 1.2484364935054015 0.5872449117315721 0.06948082115323495 0.12110390230010698 25.50113527420304 0.01909281500284583 0.041820255056020314 5.172969750229978e-06 5.286260061190108 0.20672414804511696 AVPIAVADEGES(ph)ESEDDDLKPR ddPTM_PC-9_Lapatinib_30min_R1 2 AVPIAVADEGESESEDDDLKPR 22 1 Q9Y2K6 Q9Y2K6 USP20 Ubiquitin carboxyl-terminal hydrolase 20 1 AVPIAVADEGES(0.981)ES(0.019)EDDDLKPR;AVPIAVADEGES(0.997)ES(0.003)EDDDLKPR 126.3 2.3387e-06 12173400.0 51009.0 48624.0 48207.0 48640.0 42988.0 42482.0 42641.0 41243.0 46117.0 36981.0 True False 50281.60230609506 48511.41411544968 44243.60654440134 52217.1478582834 40459.530357659794 40665.14389037881 44848.7423359846 43159.30034497386 40922.817826460916 43373.1165759149 1.1592803624818706 1.1184673351877157 1.0200698044597012 1.2039058287842657 0.9328250665788443 0.9375656420539576 1.034021667718688 0.9950703051147638 0.9435065094949936 1.0 15.404513491347961 -6.272669684753792 24.988743063188156 0.9747812568201221 1.1174076545412648 0.6671189481747528 0.05233692650074254 466.58029571222494 1038193.2285347788 0.016250812125675508 0.018591057014278486 5.337406930897772e-07 6.272669684753792 0.14262639772114272 AVPIGT(ph)PPK ddPTM_PC-9_AZD4547_30min_R2 4 AVPIGTPPK 9 0 Q86TB9-4;Q86TB9;Q86TB9-2 Q86TB9-4 PATL1 Protein PAT1 homolog 1 1 AVPIGT(1)PPK;AVPIGT(1)PPK;AVPIGT(1)PPK;AVPIGT(1)PPK 123.01 0.0037213000000000003 123614300.0 265983.0 281476.0 308014.0 294715.0 336763.0 399102.0 372965.0 376165.0 358587.0 335996.0 True False 350560.06120991055 372457.61243681563 303929.533107228 226773.01005136044 290009.27040251245 374146.0888487679 406158.1624710574 318037.34266176925 377541.1767501301 324232.88230922323 1.0811983618477625 1.1487348531220227 0.9373803512543438 0.6994139781143031 0.8944474364753928 1.1539424569897327 1.2526741876960568 0.9808916985737886 1.164413596983869 1.0 18.306670884659418 -6.765131018462224 24.999306413862488 1.118083248015311 0.9482807786230004 0.25976708924143244 0.13308371975358035 144.18869520087347 976419.9634121304 0.050813954216781955 0.04654139656293208 1.7173902047328383e-07 6.765131018462224 -0.16980246939231047 AVPIGT(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AVPIGTPPK 9 0 Q86TB9-4;Q86TB9;Q86TB9-2 Q86TB9-4 PATL1 Protein PAT1 homolog 1 1 AVPIGT(1)PPK;AVPIGT(1)PPK;AVPIGT(1)PPK 98.75399999999999 0.010662 76678000.0 133093.0 158366.0 153902.0 178697.0 238610.0 233524.0 297999.0 244785.0 244334.0 228730.0 True False 155623.01619342683 174087.5298755676 157571.6073565854 168685.18643349063 191856.08337621685 221277.59034449284 269770.37739407324 238359.65312114567 247906.92251548613 270196.93837431574 0.5759614343884067 0.6442986768206694 0.5831731784402919 0.6243045811266876 0.7100601677078596 0.8189492881593915 0.9984212960264873 0.8821700740033388 0.9175045579978028 1.0 18.043651801886433 -6.7640636984353435 1.6787639942224815 0.9420924864974853 0.6061579614018999 0.9356636819162532 0.040479179675582046 0.08317754379423083 0.48552632622263414 0.016967433277795676 0.015427869625994056 1.7216160452035873e-07 6.7640636984353435 -0.3359345250955854 AVPIGT(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 2 AVPIGTPPK 9 0 Q86TB9-4;Q86TB9;Q86TB9-2 Q86TB9-4 PATL1 Protein PAT1 homolog 1 1 AVPIGT(1)PPK;AVPIGT(1)PPK 108.43 0.0059562 47871500.0 80176.0 140340.0 124926.0 128586.0 204870.0 198438.0 200084.0 226440.0 214868.0 208126.0 True False 79032.67553752237 140015.05135246422 114655.06650830556 138042.6433903213 192819.94938991714 189951.2693215713 210443.37050146924 236961.22905986122 190667.30317965188 244100.30178953707 0.32377131432497874 0.5735963877389426 0.4697047306691206 0.5655160701494808 0.7899209791070485 0.7781689245322893 0.8621184363914192 0.970753527638687 0.7811022836999396 1.0 17.897114553210116 -6.150134075624237 0.6148173674371464 0.9355154229056337 0.3570143083427715 0.8603837086363157 0.0781726334116412 0.3526806130510266 0.26813656891382437 0.05138702967712242 0.11606394476501475 7.077272607168579e-07 6.150134075624237 -0.5785011145628622 down AVPMAPAPAS(ph)PGSSNDSSAR ddPTM_PC-9_AZD4547_30min_R2 9 AVPMAPAPASPGSSNDSSAR 20 0 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 AVPMAPAPAS(0.628)PGS(0.27)S(0.083)NDS(0.014)S(0.005)AR;AVPMAPAPAS(0.963)PGS(0.028)S(0.007)NDS(0.001)SAR;AVPMAPAPAS(0.952)PGS(0.029)S(0.01)NDS(0.01)S(0.001)AR;AVPMAPAPAS(0.951)PGS(0.024)S(0.017)NDS(0.006)S(0.001)AR;AVPMAPAPAS(0.621)PGS(0.215)S(0.075)NDS(0.044)S(0.044)AR;AVPMAPAPAS(0.875)PGS(0.094)S(0.029)NDS(0.001)SAR;AVPMAPAPAS(0.869)PGS(0.098)S(0.027)NDS(0.005)S(0.002)AR;AVPMAPAPAS(0.742)PGS(0.202)S(0.055)NDSSAR;AVPMAPAPAS(0.929)PGS(0.068)S(0.002)NDS(0.001)SAR 230.27 3.841499999999999e-102 222430000.0 237073.3 248806.09999999998 326258.6 402856.9 351983.7 307746.5 278648.8 357954.9 280926.5 310111.1 True False 312457.67796902644 329227.80615653074 321932.19779041765 309984.46578205994 303116.8389359181 288503.06270551746 303448.003385747 302641.19519029994 295775.70126718364 299254.20477947185 1.044121262053058 1.1001610032485498 1.075781702140686 1.0358566758000793 1.0129075351148122 0.9640735471641002 1.0140141676851815 1.011318104663973 0.9883760914408818 1.0 18.19101199285663 -6.043744243710953 2.1877774472856912 0.9973842542805665 1.0763513745019828 0.766539718314332 0.018615029098528423 0.1425270102090228 1.3580644472643169 0.005956201062092139 0.008974526568192155 9.041817901817353e-07 6.043744243710953 0.07896712022141628 AVPMAPAPAS(ph)PGSSNDSSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 9 AVPMAPAPASPGSSNDSSAR 20 0 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 AVPMAPAPAS(0.655)PGS(0.256)S(0.077)NDS(0.006)S(0.006)AR;AVPMAPAPAS(0.736)PGS(0.188)S(0.062)NDS(0.007)S(0.007)AR;AVPMAPAPAS(0.987)PGS(0.009)S(0.003)NDS(0.001)SAR;AVPMAPAPAS(0.982)PGS(0.011)S(0.004)NDS(0.001)S(0.001)AR;AVPMAPAPAS(0.919)PGS(0.04)S(0.04)NDS(0.001)S(0.001)AR;AVPMAPAPAS(0.971)PGS(0.022)S(0.007)NDSSAR;AVPMAPAPAS(0.933)PGS(0.051)S(0.016)NDSSAR;AVPMAPAPAS(0.419)PGS(0.419)S(0.141)NDS(0.016)S(0.006)AR;AVPMAPAPAS(0.951)PGS(0.022)S(0.022)NDS(0.002)S(0.002)AR 161.14 1.7873e-14 263092100.0 140766.3 159738.90000000002 170510.4 177795.0 207262.6 170645.3 181624.19999999998 174652.3 174256.7 147736.4 True False 164595.2543288438 175596.72231438724 174576.01460029266 167833.72256916735 166650.98137702316 161696.36006411785 164419.4409306635 170067.86218440792 176804.87457621252 174519.8398393011 0.9431320500889989 1.0061705447132987 1.000321881804632 0.9616884975582698 0.9549113815969369 0.9265213640638726 0.942124637989938 0.9744901344225815 1.013093266295772 1.0 17.41303152927147 -8.141050777538242 4.488378962826536 1.0060446452604868 0.9633370594529792 0.3518007578231147 0.023666019245156517 0.29125336639791877 9.051082441267944 0.019689830229115506 0.006908528713675315 7.2268530258396055e-09 8.141050777538242 -0.04270758580750755 AVPMAPAPAS(ph)PGSSNDSSAR ddPTM_PC-9_Lapatinib_30min_R1 9 AVPMAPAPASPGSSNDSSAR 20 0 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 AVPMAPAPAS(0.985)PGS(0.011)S(0.004)NDSSAR;AVPMAPAPAS(0.831)PGS(0.127)S(0.04)NDS(0.001)S(0.001)AR;AVPMAPAPAS(0.988)PGS(0.008)S(0.003)NDSSAR;AVPMAPAPAS(0.829)PGS(0.128)S(0.041)NDS(0.002)S(0.001)AR;AVPMAPAPAS(0.992)PGS(0.006)S(0.002)NDSSAR;AVPMAPAPAS(0.947)PGS(0.042)S(0.011)NDSSAR;AVPMAPAPAS(0.868)PGS(0.066)S(0.022)NDS(0.022)S(0.022)AR;AVPMAPAPAS(0.844)PGS(0.12)S(0.036)NDS(0.001)SAR;AVPMAPAPAS(0.757)PGS(0.073)S(0.073)NDS(0.073)S(0.023)AR 233.65 4.0373999999999994e-44 332209500.0 655605.0 615578.5 701721.0 628418.0 764234.0 772873.4 653465.9 689098.0 798952.2 616199.6 True False 646255.9524767672 614153.165804279 644028.2081013941 674633.9560609958 719283.2586618529 739819.4063378919 687299.1668687945 721116.008755931 708965.7898963543 722708.8798256437 0.894213383171214 0.8497933025984762 0.8911308911228106 0.9334795446594676 0.995260026188391 1.0236755448699844 0.9510041817039913 0.9977959713597306 0.9809839199255377 1.0 19.463055095040865 -5.945934516023051 2.233537314196191 0.9909362795343722 0.8724801165696445 0.8624312712486549 0.020343589888150604 0.10209174830711149 1.030352308947314 0.0063307890719899815 0.010251829583934691 1.1325711221864997e-06 5.945934516023051 -0.11845616296472772 AVPMAPAPASPGS(ph)SNDSSAR ddPTM_PC-9_AZD4547_30min_R2 2 AVPMAPAPASPGSSNDSSAR 20 0 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 AVPMAPAPAS(0.151)PGS(0.819)S(0.029)NDS(0.001)SAR;AVPMAPAPAS(0.098)PGS(0.664)S(0.206)NDS(0.031)S(0.001)AR 145.82 5.0343e-05 67470000.0 36936.0 49688.0 60983.0 62827.0 63198.0 55217.0 47671.0 65767.0 51694.0 50388.0 True False 48680.879683473264 65748.67429820121 60174.32557441567 48343.20581747389 54424.048576886344 51764.27226113224 51913.626649036196 55604.22132531346 54426.43930460734 48623.931456913546 1.0011711974917161 1.3521875407475468 1.237545459024372 0.9942265951964742 1.1192852356069227 1.0645842635534604 1.0676558865882266 1.1435566738280976 1.1193344033243278 1.0 15.569378925817938 -5.744168793702381 24.931153047955192 1.0800421270072613 1.2124900595118235 0.2669330145231803 0.09277945071558441 290.47354433686723 419313.0422287719 0.024215656777735614 0.04181110843048663 1.8023171127881001e-06 5.744168793702381 0.13244793250456222 AVPMAPAPASPGS(ph)SNDSSAR ddPTM_PC-9_Lapatinib_30min_R1 3 AVPMAPAPASPGSSNDSSAR 20 0 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 AVPMAPAPAS(0.078)PGS(0.803)S(0.114)NDS(0.005)SAR;AVPMAPAPAS(0.215)PGS(0.389)S(0.389)NDS(0.005)S(0.002)AR;AVPMAPAPAS(0.345)PGS(0.499)S(0.154)NDS(0.002)SAR 161.1 6.9745e-21 29095100.0 43016.8 49180.0 51729.9 43533.6 52163.0 50257.9 44687.0 46848.9 52667.4 39725.0 True False 42403.372543685044 49066.12673161021 47476.867305188614 46735.20616783241 49094.8748964038 48108.48677388703 47000.674204829724 49025.67092431794 46735.44279969092 46591.41331976473 0.9101113171361328 1.0531152252210316 1.0190046603511866 1.0030862521186212 1.053732252324208 1.032561224183314 1.0087840410046411 1.0522469148520242 1.00309133099135 1.0 15.507776473861236 -4.753330471326547 24.99999490059582 1.0264462836166652 0.9101111042742562 0.733427827153557 0.02077669175646908 144.20131276584627 444541.82563537156 0.004869958587492635 0.0527242113001014 1.764694485942837e-05 4.753330471326547 -0.116335179342409 AVPPGNDPVS(ph)PAMVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVPPGNDPVSPAMVR 15 0 A0A0A0MR08;O94966-2;O94966-7;O94966-6;O94966-5;H0YB23;E7ESU0;O94966-4;O94966-3;O94966 A0A0A0MR08 USP19 Ubiquitin carboxyl-terminal hydrolase 19;Ubiquitin carboxyl-terminal hydrolase 1 AVPPGNDPVS(1)PAMVR 82.59 0.006728499999999999 6972000.0 21930.0 19585.0 26692.0 29056.0 39334.0 34933.0 31373.0 35641.0 33023.0 23738.0 True False 25642.31586275655 21529.26936724416 27328.438509973705 27428.086520822977 31626.785061481572 33101.051983968115 28401.12231914963 34705.461514761024 33505.89890162189 28041.5114900954 0.9144412872256806 0.7677642260777761 0.9745708079832444 0.9781243971285538 1.1278559314697618 1.1804303771449627 1.0128242312894313 1.2376458924840557 1.194867791397642 1.0 14.775276494964112 -5.8775102396619365 1.415931046022427 1.1376503224718264 0.843832093737989 0.6390422440525565 0.08298829186460209 0.24815307310595164 1.0096059799051524 0.02780015374127536 0.05703058218823207 1.3258358572413144e-06 5.8775102396619365 -0.29381822873383745 AVPPVS(ph)PELR ddPTM_PC-9_AZD4547_30min_R2 4 AVPPVSPELR 10 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 AVPPVS(1)PELR;AVPPVS(1)PELR;AVPPVS(1)PELR;AVPPVS(1)PELR 123.67 0.00043826 195348000.0 130990.0 115251.0 201525.0 250925.0 212752.0 186696.0 153787.0 206026.0 155701.0 179776.0 True False 172642.09523874137 152503.63189385764 198852.6468259044 193078.1180026045 183215.05716683672 175021.8696065405 167473.74507510485 174189.41570649468 163931.03699010835 173482.09695955578 0.9951579918877148 0.8790741786422556 1.1462430435819744 1.1129570220010492 1.0561035425433554 1.0088756861599597 0.9653661559910031 1.0040771858268682 0.9449449820077164 1.0 17.404427261388165 -7.001368094921735 4.595154610675246 0.9794835212007663 1.0390603672787773 0.14171534570036826 0.06870262683842109 0.4477974004254153 24.715921637545524 0.02832072653567065 0.02339719702146734 9.968548015596075e-08 7.001368094921735 0.05957684607801095 AVPPVS(ph)PELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 AVPPVSPELR 10 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 AVPPVS(1)PELR;AVPPVS(1)PELR;AVPPVS(1)PELR;AVPPVS(1)PELR;AVPPVS(1)PELR;AVPPVS(1)PELR 123.01 0.00049114 171410200.0 163724.0 172234.0 203578.0 208161.0 238497.0 186836.0 200063.0 182657.0 173551.0 139321.1 True False 191439.2395035999 189332.25326514864 208432.07159386476 196498.41403706712 191765.22491503926 177037.99125401955 181111.5843093118 177862.44729108928 176088.85504876502 164578.91256477928 1.163206370246542 1.1504040846704846 1.266456730972898 1.1939464842418626 1.1651870943038298 1.0757027646803554 1.1004543746637354 1.0807122523736539 1.0699357062494586 1.0 17.328419970055634 -6.689415500414458 2.7042067795433935 1.0703344444983067 1.1951825902887745 0.7283515544424455 0.03762367231120685 0.15531318050639956 2.312735953958934 0.014057166535353391 0.01360246706698516 2.0444876881360173e-07 6.689415500414458 0.12484814579046777 AVPPVS(ph)PELR ddPTM_PC-9_Lapatinib_30min_R1 5 AVPPVSPELR 10 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 AVPPVS(1)PELR;AVPPVS(1)PELR;AVPPVS(1)PELR;AVPPVS(1)PELR;AVPPVS(1)PELR 136.5 0.00011546 171229000.0 183860.3 177573.4 213288.7 184724.8 183011.8 188239.0 169473.5 171685.2 196022.6 155639.7 True False 181238.4184061502 177162.23970237677 195752.92640419147 198310.07801586826 172247.4057390427 180188.45677654093 178248.00858979585 179662.32115963675 173944.47057851145 182541.81476813555 0.9928597381173134 0.9705296286629346 1.0723730705363956 1.0863816505153165 0.9436052005828429 0.9871078415946294 0.9764776843936076 0.9842255671000295 0.9529020558903479 1.0 17.477867453764688 -6.279846679312853 24.916585572403708 0.9740383083786781 1.0292382193448488 0.384934901417343 0.03496219587349418 926.3101577189153 1253873.573455327 0.0116954043624836 0.013291316999483464 5.249927677972621e-07 6.279846679312853 0.05519991096617072 AVPQGPPGLPPRPPLS(ph)SSSPQPSQPSR ddPTM_PC-9_AZD4547_30min_R2 1 AVPQGPPGLPPRPPLSSSSPQPSQPSR 27 1 Q13470-2;Q13470 Q13470-2 TNK1 Non-receptor tyrosine-protein kinase TNK1 1 AVPQGPPGLPPRPPLS(0.301)S(0.301)S(0.301)S(0.093)PQPS(0.003)QPSR 66.52 0.00016513 12404000.0 2730.0 1861.4 4673.3 6603.7 6271.6 5807.6 4862.8 7270.2 2842.1 2617.3 True False 3598.0832124724393 2463.0611483390717 4611.328988520023 5081.318991147947 5400.896595696076 5444.449853917298 5295.579779508157 6146.757642575972 2992.327603737854 2525.6691236441175 1.4246059306774943 0.9752113312393379 1.8257850742802952 2.0118704162707006 2.138402273336377 2.155646518757718 2.0967036932642715 2.433714529362908 1.1847662766769809 1.0 11.302449935290175 -5.369133724470337 5.159342797941755 1.9504767296960739 1.2052125527455642 0.24520535145307643 0.4395031024264631 0.2372804143688992 9.260013349224723 0.109551989005236 0.23582828501159367 4.274312546866638e-06 5.369133724470337 -0.7452641769505097 AVPQGPPGLPPRPPLS(ph)SSSPQPSQPSR ddPTM_PC-9_Lapatinib_30min_R1 1 AVPQGPPGLPPRPPLSSSSPQPSQPSR 27 1 Q13470-2;Q13470 Q13470-2 TNK1 Non-receptor tyrosine-protein kinase TNK1 1 AVPQGPPGLPPRPPLS(0.256)S(0.256)S(0.204)S(0.256)PQPS(0.021)QPS(0.007)R 58.418 0.0013072000000000001 11001000.0 3509.3 2072.5 5039.6 3632.5 3546.2 1459.6 3554.2 4296.2 3446.8 3863.1 True False 3459.256738473196 2067.7012535840195 4625.263541418567 3899.6461676647723 3337.61948809745 1397.1763104937836 3738.2190851658384 4495.817136049188 3058.585087586909 4530.831687742811 0.7634926602617949 0.45636240674703055 1.0208420573051127 0.8606910246113147 0.7366460990212151 0.30837082610540206 0.825062448309167 0.9922719372276955 0.6750604079734969 1.0 12.145560182979967 -8.655757176955946 0.7712517167146117 0.9883896826335373 0.7150695108568909 0.1222964075619517 0.20901541662847042 1.898611962215507 2.4334503959740363 0.21469988626245015 0.07863886888923631 2.2092396194113573e-09 8.655757176955946 -0.27332017177664647 AVPQGPPGLPPRPPLSSS(ph)SPQPSQPSR ddPTM_PC-9_AZD4547_30min_R2 1 AVPQGPPGLPPRPPLSSSSPQPSQPSR 27 1 Q13470-2;Q13470 Q13470-2 TNK1 Non-receptor tyrosine-protein kinase TNK1 1 AVPQGPPGLPPRPPLS(0.161)S(0.161)S(0.375)S(0.161)PQPS(0.095)QPS(0.048)R 52.849 0.0044001000000000005 7487000.0 7800.2 8403.7 14013.0 17475.0 14750.0 9639.9 8189.1 17576.0 11505.0 14153.0 True False 10280.501345761008 11120.031681689614 13827.178464068458 13446.408736058636 12702.217103532917 9037.115529095901 8917.914035611222 14860.033056300415 12113.130812076979 13657.507777837936 0.752736261475406 0.8142065055041822 1.0124232538608433 0.9845433701951207 0.9300538070455892 0.6616957995631125 0.652967889945656 1.0880486614412783 0.886921026084494 1.0 13.737406624188507 -7.78500006018434 24.99997746261429 0.9906135632979342 0.8395692590127607 0.2607534957753902 0.12412079311733096 403.530697643966 428175.67749643803 0.07505141786836995 0.036085470987233456 1.6405895458473382e-08 7.78500006018434 -0.15104430428517346 AVPQGPPGLPPRPPLSSS(ph)SPQPSQPSR ddPTM_PC-9_Lapatinib_30min_R1 1 AVPQGPPGLPPRPPLSSSSPQPSQPSR 27 1 Q13470-2;Q13470 Q13470-2 TNK1 Non-receptor tyrosine-protein kinase TNK1 1 AVPQGPPGLPPRPPLS(0.17)S(0.138)S(0.55)S(0.138)PQPS(0.003)QPS(0.001)R 56.946999999999996 0.0015921 8137000.0 16950.0 11366.0 11981.0 14744.0 10805.0 9763.5 12596.0 5282.5 11754.0 5859.0 True False 16708.289891750697 11339.682725324954 10995.968427997428 15828.322944542175 10169.471143447336 9345.937864830126 13248.159247298658 5527.9442347143595 10430.14074489281 6871.720343373237 2.4314566159351036 1.6501956073140271 1.6001769394765055 2.303400335522423 1.4799017764531548 1.3600579473294352 1.9279246804731451 0.8044483707846535 1.51783545076178 1.0 12.746455609345942 -1.5228787452823225 0.12466070874960788 0.7283338141405434 5.412954275690245 0.472783216122569 0.3532763560744275 80.44952022493081 0.6870301902391609 2.1427009601711333 65.77200465557195 0.029999999999862886 1.5228787452823225 4.684620461549701 AVPS(ph)PPPPPIVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVPSPPPPPIVK 12 0 A0A286YF23;A0A0J9YY01;A0A2R8YFM0;Q96JP2 A0A286YF23 MYO15B Unconventional myosin-XVB 1 AVPS(1)PPPPPIVK 90.61399999999999 0.024191 0.0 15539.0 21277.0 15829.0 21623.0 28692.0 27252.0 19302.0 18493.0 19867.0 16587.0 True False 18169.445790760332 23389.239945205733 16206.423391816785 20411.533412711862 23070.00856724537 25822.857145595848 17473.574825621592 18007.57834495315 20157.517290328626 19594.091797380253 0.927292062252643 1.1936883927599489 0.8271076587476025 1.0417187805275518 1.1773961664469619 1.317889974826411 0.8917777361825887 0.9190310289023336 1.0287548664553925 1.0 14.258131083911824 AVPS(ph)PTTGEEGSVHSR ddPTM_PC-9_AZD4547_30min_R2 1 AVPSPTTGEEGSVHSR 16 0 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 AVPS(0.831)PT(0.169)TGEEGSVHSR 154.56 2.018e-05 13280000.0 17233.0 18687.0 54032.0 121780.0 75933.0 54048.0 40510.0 81889.0 51169.0 69286.0 True False 22712.735531332444 24727.207305797903 53315.50037611837 93705.50248224438 65391.01364898744 50668.37001593123 44115.3115217314 69234.93667201795 53873.68887641612 66860.31822901723 0.3397042690334544 0.3698338261134143 0.7974161922696258 1.4015114639639332 0.9780242658283952 0.7578242425107284 0.6598130653614726 1.0355161103910233 0.8057647690500381 1.0 16.028862601186376 -5.319024932576009 4.068085468757667 0.9406371331753692 0.3463246538825352 0.5998533691427423 0.1903239537477058 0.1499543334592145 5.0738798604709485 0.05447913094092967 0.12805976727310775 4.797059082284162e-06 5.319024932576009 -0.594312479292834 AVPS(ph)PTTGEEGSVHSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVPSPTTGEEGSVHSR 16 0 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 AVPS(0.912)PT(0.088)T(0.001)GEEGSVHSR 69.024 0.01259 9705100.0 8502.5 16692.0 23117.0 23873.0 25613.0 32564.0 26117.0 27193.0 25232.0 21973.0 True False 9941.805317970251 18349.07144641509 23668.196951710695 22535.47320731027 20594.316514458933 30856.286514354266 23643.008689294318 26479.2125633651 25600.970265745796 25956.530961827702 0.3830174892242306 0.7069153991879606 0.9118397595779542 0.8682005018487055 0.7934155972053981 1.1887677347844463 0.9108693578531081 1.0201368049646569 0.9863016865926806 1.0 14.663809962478517 -4.652928470353082 0.9485286463157087 0.9834421595080489 1.6130243952663e-24 0.7848374534028764 0.09586632450067942 1.1701003660363924 0.7097636611183976 0.032644413241645104 1.256046967498781 2.2236761068374075e-05 4.652928470353082 -0.9834421595080489 down AVPS(ph)PTTGEEGSVHSR ddPTM_PC-9_Lapatinib_30min_R1 1 AVPSPTTGEEGSVHSR 16 0 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 AVPS(0.842)PT(0.158)TGEEGSVHSR 163.44 3.6665e-05 5156900.0 15681.0 11222.0 21681.0 14181.0 22694.0 22948.0 19558.0 15278.0 31434.0 14281.0 True False 15457.386064456798 11196.016148477625 19898.471871080234 15223.918046429224 21359.183538120673 21966.56753440077 20570.617541971038 15987.871655081126 27893.571905305475 16749.451821763632 0.9228592212416187 0.6684407506357866 1.188007349901737 0.9089203759282328 1.2752168707018412 1.3114797886016905 1.2281367629740767 0.954531039296884 1.6653423767016409 1.0 14.031826259181676 -5.670912407898499 1.0953488502975295 1.2372465575814475 0.7910517494761693 0.33673792247544543 0.21593124079550546 0.6709458458111308 1.4914596349544094 0.07518915515652741 0.2451247629368322 2.1334751666660096e-06 5.670912407898499 -0.44619480810527823 AVPS(ph)SPAGSAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVPSSPAGSAAR 12 0 F8WBN8;B0QYH1;Q8IWD4-4;Q8IWD4-3;Q8IWD4 F8WBN8 CCDC117 Coiled-coil domain-containing protein 117 1 AVPS(0.596)S(0.404)PAGSAAR 96.23 0.0043487 13953000.0 43385.0 58535.0 63436.0 60245.0 85949.0 58547.0 61492.0 57299.0 56783.0 49963.0 True False 50729.223607190725 64345.967955661865 64948.55482236973 56869.66796692527 69107.91044005915 55476.69225389695 55667.032596473044 55794.96196330889 57613.343952118055 59020.89639310959 0.8595129302901119 1.0902234952021832 1.1004332158864358 0.9635514104723854 1.1709058090166038 0.9399500116771116 0.9431749769725948 0.9453425036394852 0.9761516254918171 1.0 15.84893821174047 AVPS(ph)SPAGSAAR ddPTM_PC-9_Lapatinib_30min_R1 1 AVPSSPAGSAAR 12 0 F8WBN8;B0QYH1;Q8IWD4-4;Q8IWD4-3;Q8IWD4 F8WBN8 CCDC117 Coiled-coil domain-containing protein 117 1 AVPS(0.595)S(0.4)PAGS(0.005)AAR 107.39 0.0015578 13419000.0 60980.0 57720.0 67415.0 52914.0 61911.0 56999.0 49731.0 41790.0 60643.0 51009.0 True False 60110.41401763762 57586.352886306195 61872.3989294255 56805.47207592949 58269.51670170917 54561.28564115866 52305.82784434819 43731.71596189553 53812.74674089961 59825.83768477989 1.0047567463134766 0.9625665952180484 1.0342086517104676 0.9495140272875977 0.9739858054095136 0.9120020337807895 0.8743016373618644 0.730983763107778 0.8994900668911142 1.0 15.868481072152619 -6.930674253601672 1.9958234469326879 0.8539306184708393 0.9875818379449994 0.3672168971926474 0.06584408558632496 0.29913293127437274 2.421996404052589 0.027454284460425537 0.022381574429223283 1.1730749108125166e-07 6.930674253601672 0.13365121947416014 AVPSPT(ph)TGEEGSVHSR ddPTM_PC-9_AZD4547_30min_R2 1 AVPSPTTGEEGSVHSR 16 0 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 AVPS(0.411)PT(0.588)T(0.001)GEEGSVHSR 135.95 2.52e-06 0.0 2737.3 8519.9 16888.0 35753.0 31632.0 23060.0 13806.0 23257.0 14508.0 25873.0 True False 3607.704460623008 11273.791059274768 16664.05408557683 27510.698228343586 27240.44280806463 21618.054554606548 15034.7072542341 19663.165042693385 15274.863261330978 24967.194145128287 0.1444977933704641 0.4515441740767078 0.6674379983875119 1.1018738456724662 1.0910494246859497 0.8658583911730731 0.6021784893745356 0.7875600649554828 0.6117973518586781 1.0 14.607746077453122 -5.118605077582552 2.010099557529327 0.8536007536341977 0.14567893946429217 0.6519888293545588 0.16870563485560786 0.2821858764295094 1.907680211596866 0.051804503058690575 0.2838452256238766 7.6101798836947885e-06 5.118605077582552 -0.7079218141699055 AVPSS(ph)PAGSAAR ddPTM_PC-9_AZD4547_30min_R2 1 AVPSSPAGSAAR 12 0 F8WBN8;B0QYH1;Q8IWD4-4;Q8IWD4-3;Q8IWD4 F8WBN8 CCDC117 Coiled-coil domain-containing protein 117 1 AVPS(0.224)S(0.775)PAGS(0.001)AAR 81.278 0.013378 15470000.0 31516.0 33118.0 46736.0 58307.0 45508.0 43748.0 32464.0 44903.0 35632.0 51352.0 True False 41537.43242647672 43822.74584221197 46116.250103240105 44865.22198417 39189.99972525941 41012.43064418588 35353.23310889874 37964.273118289566 37515.43477583025 49554.18211033229 0.8382225406120862 0.8843400087734414 0.9306227676316474 0.9053771058974937 0.7908515095255322 0.8276280406136415 0.7134258220665379 0.76611643057214 0.7570589035714929 1.0 15.596719197914423 -6.265251474012933 24.163022156087937 0.7936206151403393 0.8921892912546651 0.19810867532718301 0.07543615876763493 267.0219856923351 1692520.716376277 0.022116355208954157 0.02605353626734648 5.429358587051985e-07 6.265251474012933 0.09856867611432574 AVPTWASVQVVDDPGS(ph)LASVESPGTPK ddPTM_PC-9_Lapatinib_30min_R1 1 AVPTWASVQVVDDPGSLASVESPGTPK 27 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 AVPTWASVQVVDDPGS(0.316)LAS(0.316)VES(0.316)PGT(0.051)PK 69.771 0.0001273 1602400.0 7344.4 8852.0 9260.9 7709.8 11802.0 10120.0 14893.0 11927.0 12883.0 14139.0 True False 7239.667509201995 8831.503737865254 8499.504550107788 8276.804411138854 11107.829563624751 9687.191190872218 15664.086667991342 12481.17196165418 11431.980875995747 16582.90731096675 0.43657408037336104 0.5325666707444434 0.5125461048972288 0.4991166057875247 0.6698360761070422 0.5841672397496789 0.9445923066597757 0.7526528206184945 0.6893833910797686 1.0 14.017409341474503 -6.587812658104892 0.21277592404104817 1.0464945180894987 0.22638152478426085 0.7447789592179495 0.09116291332654605 2.8019071733354743 0.27094563330952603 0.25186145125028564 0.6888716922089605 2.583374342193198e-07 6.587812658104892 -0.8201129933052378 down AVPTWASVQVVDDPGSLASVES(ph)PGTPK ddPTM_PC-9_Lapatinib_30min_R1 1 AVPTWASVQVVDDPGSLASVESPGTPK 27 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 AVPTWASVQVVDDPGS(0.01)LAS(0.029)VES(0.61)PGT(0.351)PK 68.28399999999999 0.0035231999999999998 0.0 8391.4 10711.0 10422.0 12105.0 12102.0 13987.0 12354.0 12908.0 13883.0 13211.0 True False 8271.737097205709 10686.199337581884 9565.143390083409 12995.242081096238 11390.18415344745 13388.808615289505 12993.629671413752 13507.75280297075 12319.35034552891 15494.503747449015 0.5338497593746784 0.6896767726001705 0.6173249266959063 0.8387001154029053 0.7351112587470062 0.8641005116084348 0.8385960520712383 0.8717770522463257 0.7950787289691124 1.0 13.919468929080924 -3.7069385715550816 0.23298117096359552 0.954647150546046 2.9209128756681155e-13 0.7773903232416142 0.061191366876182623 8.486484048237577 0.26602409441148317 0.08965723496500123 2.5291512005990398 0.0001963638002442914 3.7069385715550816 -0.9546471505457539 AVPTWASVQVVDDPGSLASVESPGT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AVPTWASVQVVDDPGSLASVESPGTPK 27 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 AVPTWASVQVVDDPGS(0.017)LAS(0.018)VES(0.105)PGT(0.86)PK;AVPTWASVQVVDDPGS(0.003)LAS(0.008)VES(0.178)PGT(0.811)PK 128.65 3.3996e-10 2497100.0 20190.1 22172.2 21527.2 25258.4 36642.7 33888.8 40058.3 44746.7 36134.1 32141.0 True False 23607.885157347955 24373.309485035017 22040.49009036064 23843.253736837676 29462.825976822878 32111.611670177186 36263.68782702295 43572.146538047666 36662.492853498945 37967.908871983986 0.6217852354457134 0.6419450059052306 0.5805031339670125 0.6279843806312783 0.775992854285507 0.8457566567189039 0.9551141715308278 1.1476045911551103 0.965617911092062 1.0 15.212492922538697 -6.851753284974661 1.2063380373095232 1.043895237052915 0.6116233236554518 0.918371687397965 0.05321087007847146 0.11501571406745509 0.3506821618821073 0.02802641567575894 0.023199780747392394 1.4068465018180283e-07 6.851753284974661 -0.4322719133974633 AVPVES(ph)PVQKV ddPTM_PC-9_AZD4547_30min_R2 3 AVPVESPVQKV 11 1 Q8TB61-5;Q8TB61-4;Q8TB61-3;Q8TB61-2;Q8TB61 Q8TB61-5 SLC35B2 Adenosine 3-phospho 5-phosphosulfate transporter 1 1 AVPVES(1)PVQKV;AVPVES(1)PVQKV;AVPVES(1)PVQKV 150.51 0.00049648 89729700.0 503812.0 573699.0 690247.0 772415.0 710062.0 505067.0 620976.0 659945.0 517582.0 530365.0 True False 664013.7360594022 759135.9824545915 681093.8737806219 594346.6554427885 611482.1478622905 473485.0806475057 676241.6610100889 557965.6642774328 544940.3278554042 511797.0827805428 1.2974160236550811 1.4832753214033207 1.3307888940677552 1.1612935584035806 1.1947745863266133 0.9251422029901152 1.3213081585696718 1.090208762515919 1.064758565826123 1.0 18.965212398543287 -5.780049346119072 2.2542614549577276 1.1080264824479629 1.397195828457061 0.5585993093451904 0.10861257969376036 0.2192311480698463 2.2736216771954667 0.031746628371315755 0.05893793166164148 1.6593983498477768e-06 5.780049346119072 0.28916934600909805 AVPVES(ph)PVQKV ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AVPVESPVQKV 11 1 Q8TB61-5;Q8TB61-4;Q8TB61-3;Q8TB61-2;Q8TB61 Q8TB61-5 SLC35B2 Adenosine 3-phospho 5-phosphosulfate transporter 1 1 AVPVES(1)PVQKV;AVPVES(1)PVQKV;AVPVES(1)PVQKV;AVPVES(1)PVQKV 150.51 0.00014543 81159000.0 661382.0 543711.0 545684.0 543267.0 827972.0 542425.0 548122.0 465537.0 480763.0 441218.0 True False 773340.9097100608 597687.034819183 558695.1760780953 512829.5112853786 665736.8302467329 513979.2781153609 496199.9161003696 453317.1470272245 487793.2493607622 521207.33072023396 1.483749103531246 1.1467356646600981 1.0719250155327986 0.9839261289297708 1.2772975186799078 0.9861320971927142 0.9520202170117068 0.8697443806110805 0.9358909988597085 1.0 18.991497849822814 -1.5228787452803376 0.567377934113485 0.9729110125834185 24.80151639555039 0.6789264822742596 0.09999057558944854 93.79247516044231 0.8120423986561425 0.05165908743336566 2741.339141372907 0.029999999999999995 1.5228787452803376 23.828605382966973 AVPVES(ph)PVQKV ddPTM_PC-9_Lapatinib_30min_R1 4 AVPVESPVQKV 11 1 Q8TB61-5;Q8TB61-4;Q8TB61-3;Q8TB61-2;Q8TB61 Q8TB61-5 SLC35B2 Adenosine 3-phospho 5-phosphosulfate transporter 1 1 AVPVES(1)PVQKV;AVPVES(1)PVQKV;AVPVES(1)PVQKV;AVPVES(1)PVQKV 145.14 0.00010016 88003000.0 1040631.0 1018337.0 652293.0 484634.0 621341.0 582931.0 459208.0 482495.0 711297.0 366547.0 True False 1025791.4111116467 1015979.1032429392 598663.9874637958 520275.6010516309 584794.9439834071 558000.4000085316 482983.54331800016 504913.4791345968 631183.241570531 429904.16055682406 2.386093239439722 2.363268831655442 1.3925522067253064 1.210212993467556 1.3602914268751531 1.2979646423653908 1.1234679438608506 1.174479164101642 1.4681952385689978 1.0 18.71365554704147 -5.289702775808468 3.8677998139173155 1.2477329165436923 2.4018718324000012 0.931268351690863 0.12240739356732519 0.04595452332883825 1.5306621561985765 0.03164728572561543 0.0792126648835111 5.132124982478253e-06 5.289702775808468 1.154138915856309 AVQGTDGGGGSNS(ph)SSR ddPTM_PC-9_Lapatinib_30min_R1 1 AVQGTDGGGGSNSSSR 16 0 Q9BXB5-2;Q9BXB5 Q9BXB5-2 OSBPL10 Oxysterol-binding protein-related protein 10 1 AVQGTDGGGGS(0.192)NS(0.616)S(0.192)SR 137.32 1.0068e-06 0.0 5692.3 4024.2 3918.7 3027.2 3026.9 2173.4 911.27 2186.6 2634.0 1124.5 True False 5611.126758160024 4014.8822121461126 3596.519612619441 3249.830386443166 2848.863693114368 2080.448748442854 958.4511017216452 2288.1974185757554 2337.3311827503526 1318.8683266979344 4.254501108695715 3.0441873012434977 2.7269739820229724 2.4641052640787904 2.160081969856005 1.5774499291007293 0.7267223591011015 1.734970331954776 1.772224819897188 1.0 10.36508482051581 -1.5228787452803376 0.3042784139973769 1.1248864173319337 28.520891612615554 0.8777395203605517 0.34350203275290586 18.846400432251528 0.2688651161669856 0.3726381987143786 282.39863138251195 0.029999999999999995 1.5228787452803376 27.39600519528362 up AVQGTDGGGGSNSS(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 1 AVQGTDGGGGSNSSSR 16 0 Q9BXB5-2;Q9BXB5 Q9BXB5-2 OSBPL10 Oxysterol-binding protein-related protein 10 1 AVQGTDGGGGS(0.041)NS(0.057)S(0.684)S(0.218)R 122.5 0.0006806 0.0 5185.2 3866.2 4359.9 3136.0 2664.2 2644.8 2471.2 2236.7 4055.8 1272.4 True False 5111.258097150777 3857.2480514386193 4001.4458517006965 3366.631901389325 2507.496994018731 2531.688069329927 2599.1466443255354 2340.625247474796 3598.993094532606 1492.3326446335736 3.425012590544645 2.584710630910125 2.681336407194395 2.255952728432048 1.6802533959407022 1.6964636392790002 1.7416670831882313 1.5684339921743866 2.411656079141993 1.0 10.543353436390145 -1.5228787453109431 0.31407036497415974 1.50918620224563 19.144003220465734 0.7386318832735215 0.33949655683136587 28.625200589811605 0.40874035421024657 0.32326894444377274 288.09408430142275 0.029999999997885843 1.5228787453109431 17.634817018220105 AVQLMQQVASNGATLPSALSAS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 AVQLMQQVASNGATLPSALSASK 23 0 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L2M4 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 AVQLMQQVAS(0.002)NGAT(0.091)LPS(0.015)ALS(0.192)AS(0.7)K 78.128 0.0018909000000000003 0.0 6062.3 6990.2 5817.3 5806.0 6035.2 8245.4 8768.5 8691.2 8878.1 9294.6 True False 7989.985296326623 9249.645449188669 5740.158801043702 4467.516401805802 5197.316655135044 7729.81383454262 9548.879513164688 7348.174743907496 9347.37824099963 8969.198883056055 0.890824855207605 1.0312677386006472 0.6399856749622961 0.49809536615867694 0.5794627505644265 0.8618176422807627 1.0646301456425191 0.8192676781634447 1.042164229255525 1.0 13.130763415954174 -6.995175183342895 23.54233486255978 0.9659929958461205 0.7264768534713033 0.37288534323295064 0.15471776333060858 83.28445538436463 406373.1471534169 0.0614606921895022 0.05396923796736722 1.011171491135314e-07 6.995175183342895 -0.23951614237481722 AVQLMQQVASNGATLPSALSAS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 AVQLMQQVASNGATLPSALSASK 23 0 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L2M4 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 AVQLMQQVASNGAT(0.022)LPS(0.342)ALS(0.26)AS(0.377)K 67.075 0.0082251 0.0 8946.5 10213.0 8775.3 12021.0 11410.0 10904.0 10089.0 8726.4 11641.0 9475.5 True False 8818.921269412836 10189.35242598485 8053.828707637585 12905.064440880456 10738.886232923101 10437.66133846549 10611.359054143873 9131.860401289423 10329.867994835553 11113.327549689893 0.7935446183855995 0.9168588238244785 0.7247000209097876 1.1612241592969659 0.9663070025523327 0.939202168909054 0.9548318455204691 0.8217035231310391 0.9295027028267333 1.0 13.440003232339556 -5.725660617894807 24.999995958838365 0.9583488028572865 0.822217042135663 0.37877712951638887 0.09062479571063743 218.77374248889984 152864.0904818496 0.025148627231965398 0.04355676901491473 1.8807859945111148e-06 5.725660617894807 -0.13613176072162347 AVQQHQHGYDS(ph)DEEVDSELGTWEHQLR ddPTM_PC-9_AZD4547_30min_R2 2 AVQQHQHGYDSDEEVDSELGTWEHQLR 27 0 Q8IWZ8 Q8IWZ8 SUGP1 SURP and G-patch domain-containing protein 1 1 AVQQHQHGY(0.047)DS(0.953)DEEVDSELGTWEHQLR;AVQQHQHGY(0.182)DS(0.814)DEEVDS(0.004)ELGTWEHQLR 78.45100000000001 2.9542e-05 7930800.0 7809.0 6258.5 9902.1 13877.400000000001 10298.7 10021.2 10051.0 12456.900000000001 9006.8 11548.4 True False 10292.09956270963 8281.437733362029 9770.791684082793 10678.179833692719 8868.903273502 9394.572779818864 10945.519528632984 10531.972336084933 9482.881060253367 11144.094031059392 0.9235474444153835 0.7431234616543135 0.8767685966082925 0.9581918282394121 0.7958388765191434 0.8430091090074718 0.9821811892583671 0.9450720988831903 0.8509333314869647 1.0 13.4439917157501 -9.873440822203532 0.1206179021273425 1.135749178006884 0.7764301369704987 0.23911531295585553 0.06962985943463794 40.5283253857293 1.3288134037255688 2.9316890013249246 1.0648109895284708 1.3383175644402768e-10 9.873440822203532 -0.35931904103638534 AVQQHQHGYDS(ph)DEEVDSELGTWEHQLR ddPTM_PC-9_Lapatinib_30min_R1 1 AVQQHQHGYDSDEEVDSELGTWEHQLR 27 0 Q8IWZ8 Q8IWZ8 SUGP1 SURP and G-patch domain-containing protein 1 1 AVQQHQHGY(0.18)DS(0.805)DEEVDS(0.014)ELGTWEHQLR 47.714 0.024232 4360600.0 8045.2 14521.0 12063.0 12394.0 13645.0 11873.0 11211.0 11514.0 13838.0 10473.0 True False 7930.473972691013 14487.377516667582 11071.226704526587 13305.496105171967 12842.427927102162 11365.219467314808 11791.450724155706 12048.982473923554 12279.418719399919 12283.244095604683 0.6456335078066857 1.1794422877138464 0.9013275823842178 1.0832232919586022 1.045524116198063 0.9252620381761874 0.9599622569069554 0.9809283590020852 0.9996885695525555 1.0 13.584404017011902 -4.742777816912763 24.96923932923044 1.0038219614586708 0.6456323290760555 0.6707335862711963 0.07618558252956122 728.5075918795558 974694.3698848407 0.01806891536897752 0.6236176519865877 1.80809890463362e-05 4.742777816912763 -0.35818963238261525 AVQTLAGSQPTSDKPSQRPS(ph)ESTNCSPTR ddPTM_PC-9_AZD4547_30min_R2 1 AVQTLAGSQPTSDKPSQRPSESTNCSPTR 29 2 Q9NR48-2;Q9NR48 Q9NR48-2 ASH1L Histone-lysine N-methyltransferase ASH1L 1 AVQTLAGS(0.002)QPT(0.019)S(0.007)DKPS(0.034)QRPS(0.242)ES(0.242)T(0.242)NCS(0.188)PT(0.026)R 48.025 0.0062834 7808300.0 6719.6 5074.6 9412.3 12129.0 11826.0 8969.6 7837.1 10563.0 9429.1 9948.1 True False 8856.29302363729 6714.865210788357 9287.486752112434 9332.84644118198 10184.164031619006 8408.729494058922 8534.586717525577 8930.731063592479 9927.502976110833 9599.820046965979 0.9225478165537405 0.6994782379186982 0.9674646719078597 0.9721897280909578 1.0608703060884677 0.8759257416201774 0.8890361148199785 0.9303019244006594 1.0341342783033123 1.0 13.228791646768476 -5.292041671947316 24.68612739092658 0.9613604522146767 0.8110130184686155 0.40992976123162395 0.07431039365728635 493.65503705235443 398218.7536601799 0.01928827723460266 0.04015986149919827 5.104560177346898e-06 5.292041671947316 -0.1503474337460612 AVQTLAGSQPTSDKPSQRPS(ph)ESTNCSPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVQTLAGSQPTSDKPSQRPSESTNCSPTR 29 2 Q9NR48-2;Q9NR48 Q9NR48-2 ASH1L Histone-lysine N-methyltransferase ASH1L 1 AVQTLAGSQPTSDKPS(0.026)QRPS(0.221)ES(0.221)T(0.221)NCS(0.221)PT(0.089)R 68.959 4.0876e-05 9187800.0 9348.2 7264.6 8917.9 9665.4 10765.0 10279.0 11208.0 7194.3 7835.4 7485.0 True False 10930.665624633866 7985.781477931172 9130.536557324082 9123.878973649591 8655.6755271991 9739.951144854676 10146.297101106966 7005.457247990941 7949.977901879542 8841.971248772606 1.236224968063677 0.903167546381664 1.0326358569183915 1.0318829044955464 0.9789305216753146 1.1015587894166385 1.1475152786224474 0.7922958637717127 0.8991182710510525 1.0 13.110152327784578 -7.762236753699301 24.999992696784798 0.8842803068738293 1.0516893528795306 0.3672938621757279 0.0979302232711865 22.243736304448245 697317.0567343232 0.04842786094611561 0.025400530375231843 1.728873614533944e-08 7.762236753699301 0.16740904600570128 AVQTLAGSQPTSDKPSQRPS(ph)ESTNCSPTR ddPTM_PC-9_Lapatinib_30min_R1 2 AVQTLAGSQPTSDKPSQRPSESTNCSPTR 29 2 Q9NR48-2;Q9NR48 Q9NR48-2 ASH1L Histone-lysine N-methyltransferase ASH1L 1 AVQTLAGSQPT(0.07)S(0.021)DKPS(0.07)QRPS(0.192)ES(0.192)T(0.192)NCS(0.192)PT(0.07)R;AVQTLAGS(0.002)QPT(0.01)S(0.01)DKPS(0.19)QRPS(0.376)ES(0.121)T(0.121)NCS(0.121)PT(0.05)R 45.14 0.0088255 19266300.0 24937.7 28782.0 35059.0 30377.0 35215.0 32244.0 27208.0 23356.1 38247.0 25472.6 True False 24582.083824985923 28715.357047360812 32176.584351653633 32611.025914701393 33143.7229353538 30864.999284435155 28616.697110233552 24441.309671635034 33939.22010123489 29875.504969894013 0.8228173498576058 0.9611672531158119 1.0770222757432368 1.0915640069536567 1.109394568183976 1.033120588774592 0.9578648842612374 0.8181053239523449 1.136021638309911 1.0 14.86667547796183 -4.840829197069111 3.20027873733149 1.02418510833473 0.8066984495983645 0.34060974314759673 0.08656396335413279 0.3723610052699739 6.173590264729376 0.02351957167331438 0.1884669721211835 1.4426826301393488e-05 4.840829197069111 -0.21748665873636552 AVQTLAGSQPTSDKPSQRPSES(ph)TNCSPTR ddPTM_PC-9_AZD4547_30min_R2 1 AVQTLAGSQPTSDKPSQRPSESTNCSPTR 29 2 Q9NR48-2;Q9NR48 Q9NR48-2 ASH1L Histone-lysine N-methyltransferase ASH1L 1 AVQTLAGS(0.001)QPT(0.027)S(0.01)DKPS(0.077)QRPS(0.077)ES(0.238)T(0.238)NCS(0.238)PT(0.096)R 41.047 0.021603 7501700.0 9373.6 8339.4 9595.3 12993.0 12505.0 11521.0 10333.0 13294.0 9323.5 13639.0 True False 12354.209817007933 11034.947964144656 9468.060052542354 9997.664589848915 10768.89660201215 10800.59004872602 11252.616982326594 11239.71776572928 9816.321175697507 13161.502761388498 0.9386625555594689 0.8384261405557387 0.7193753041877949 0.7596142151167389 0.818211780010755 0.8206198216522345 0.8549644509696913 0.8539843792536289 0.7458358937928693 1.0 13.684036602864781 -7.097458168879771 2.595417077365209 0.8518556325304655 0.8079747432451806 0.07114885855514541 0.0784348297659305 0.9809969870005022 12.914149256865237 0.03416236303461295 0.025629825300631178 7.989908965357422e-08 7.097458168879771 -0.043880889285284885 AVQTLAGSQPTSDKPSQRPSES(ph)TNCSPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVQTLAGSQPTSDKPSQRPSESTNCSPTR 29 2 Q9NR48-2;Q9NR48 Q9NR48-2 ASH1L Histone-lysine N-methyltransferase ASH1L 1 AVQTLAGSQPT(0.017)S(0.006)DKPS(0.143)QRPS(0.131)ES(0.44)T(0.131)NCS(0.099)PT(0.032)R 55.62 0.00075531 7788900.0 8693.5 9022.8 11559.0 8569.5 9567.9 11313.0 11252.0 11329.0 8129.1 7213.6 True False 10165.137845548294 9918.523954392163 11834.610397751618 8089.378697693854 7693.138678744838 10719.726364601705 10186.129102574556 11031.625754067709 8247.972708753732 8521.368577173816 1.192899679609874 1.163959035988762 1.3888156920536192 0.9493051056801916 0.9028055304816227 1.257981774584499 1.1953630464782539 1.2945838047210065 0.9679164366681158 1.0 13.056869438228283 -14.522878745260464 0.18569515459723598 0.36659890337406537 1.1785372273348884 0.095900510923847 0.14951361911326982 391.60425898827833 3.795051247796338 91.47962048429682 0.4540760527033534 3.000000000137285e-15 14.522878745260464 0.8119383239608231 AVQTLAGSQPTSDKPSQRPSESTNCS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 1 AVQTLAGSQPTSDKPSQRPSESTNCSPTR 29 2 Q9NR48-2;Q9NR48 Q9NR48-2 ASH1L Histone-lysine N-methyltransferase ASH1L 1 AVQTLAGS(0.001)QPT(0.004)S(0.004)DKPS(0.088)QRPS(0.068)ES(0.021)T(0.021)NCS(0.567)PT(0.226)R 60.278999999999996 0.015996 0.0 3312.5 2364.5 3875.9 5325.3 4257.3 4151.1 2471.8 4668.2 2847.8 4294.9 True False 4365.806095719765 3128.7783846823545 3824.503033531928 4097.634360064839 3666.247381347166 3891.5310607817523 2691.785411488908 3946.8369545642695 2998.3288941010737 4144.53685826582 1.0533881697812983 0.7549162890040059 0.922781764120249 0.9886832956721233 0.8845976056492878 0.9389543859455669 0.6494779763197037 0.9522986740225846 0.7234412424445541 1.0 12.016995177790823 AVQTRPVLQPQPGS(ph)LNSSIWDGSEVLR ddPTM_PC-9_AZD4547_30min_R2 1 AVQTRPVLQPQPGSLNSSIWDGSEVLR 27 1 Q86TB9-4;Q86TB9 Q86TB9-4 PATL1 Protein PAT1 homolog 1 1 AVQTRPVLQPQPGS(0.968)LNS(0.026)S(0.005)IWDGSEVLR 111.84 6.9835e-11 5231800.0 5325.4 1643.2 10337.0 12561.0 7451.9 12344.0 8740.2 11516.0 6883.9 11181.0 True False 7018.766424798807 2174.3322654726353 10199.92462592419 9665.255515515455 6417.332314157081 11572.12772862372 9518.060867989057 9736.466811353876 7247.7689002396155 10789.556593231531 0.6505148162624028 0.20152192971828242 0.9453516034498372 0.8957972861997527 0.5947725709305589 1.0725304259382733 0.8821549602844565 0.9023973068051493 0.6717392728433588 1.0 13.397347956711771 -5.273344824438621 24.975364217887257 0.8657815407487246 0.42601836478761707 0.528912192550687 0.16777856815794007 471.1759688212226 988438.2574358692 0.04182542736948808 0.08816408276897102 5.329116022545489e-06 5.273344824438621 -0.43976317596110753 AVQTRPVLQPQPGSLNS(ph)SIWDGSEVLR ddPTM_PC-9_AZD4547_30min_R2 1 AVQTRPVLQPQPGSLNSSIWDGSEVLR 27 1 Q86TB9-4;Q86TB9 Q86TB9-4 PATL1 Protein PAT1 homolog 1 1 AVQT(0.001)RPVLQPQPGS(0.383)LNS(0.384)S(0.167)IWDGS(0.065)EVLR 53.097 0.0039728 5074000.0 7827.1 5455.3 9303.8 14537.0 9142.9 9233.9 8855.1 8162.6 7995.9 7979.4 True False 10315.954986206238 7218.619040794098 9180.425533005071 11185.719244411119 7873.566152941776 8656.50277327759 9643.186745398261 6901.257727887902 8418.546950046624 7700.043634740334 1.33972682176289 0.9374776797661003 1.1922562998975343 1.4526825788290914 1.0225352642702645 1.1242147686309198 1.2523548180806452 0.8962621584053699 1.093311590088219 1.0 12.91065090598198 -7.756128096847792 24.996915008332536 0.9960901507804055 1.1804965903875713 0.2673362060596247 0.14537949696612656 181.02261073381743 851973.4619162213 0.07048888592436722 0.03915422200787926 1.7533632642456844e-08 7.756128096847792 0.18440643960716574 AVS(ph)EEQQPALK ddPTM_PC-9_AZD4547_30min_R2 4 AVSEEQQPALK 11 0 Q5STZ8;Q8NE71-2;Q8NE71;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 AVS(1)EEQQPALK;AVS(1)EEQQPALK;AVS(1)EEQQPALK;AVS(1)EEQQPALK 135.94 0.00010083 20247500.0 65765.0 73528.0 93077.0 168307.0 147807.0 114757.0 89662.0 123674.0 92869.0 107611.0 True False 86676.9020030219 97294.48808159202 91842.73816456861 129506.4214672287 127286.54938453504 107581.2266488719 97641.74430169043 104563.02504579553 97777.86574417885 103843.5716442393 0.8346872187714306 0.9369331826809273 0.8844335447091064 1.2471298840809184 1.225752806544537 1.0359931283704065 0.9402772146185814 1.0069282420679926 0.9415880462890748 1.0 16.664052384466018 -5.6411732288772365 22.58865135168694 1.0590044084164794 0.890443366092632 0.3740607853675467 0.101544343416192 4.616653014682822 873.979933852396 0.030835692538296412 0.05340897452732957 2.284687318707686e-06 5.6411732288772365 -0.1685610423238474 AVS(ph)EEQQPALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVSEEQQPALK 11 0 Q5STZ8;Q8NE71-2;Q8NE71;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 AVS(1)EEQQPALK 134.56 6.2859e-05 5370200.0 24027.0 19640.0 19777.0 22091.0 24559.0 25970.0 18732.0 26096.0 17252.0 18399.0 True False 28094.296545118606 21589.729403761834 20248.558684690157 20853.31288998833 19746.840248256627 24608.087482427854 16957.569352064213 25411.007650997522 17504.27786242258 21734.59305359615 1.2926074334973665 0.9933348809670791 0.9316281484892989 0.9594526494499052 0.9085442823595616 1.1322083381890724 0.7802110354791509 1.169150376468313 0.805364877053742 1.0 14.407705463200646 -4.76279632774998 4.523353593821605 0.9644049583644718 1.3195110795162956 0.4203606838049685 0.11610174635311642 0.1819683300594313 8.283975484850624 0.0261006402311028 0.210689979218534 1.726647452639389e-05 4.76279632774998 0.35510612115182383 AVS(ph)EEQQPALK ddPTM_PC-9_Lapatinib_30min_R1 3 AVSEEQQPALK 11 0 Q5STZ8;Q8NE71-2;Q8NE71;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 AVS(1)EEQQPALK;AVS(1)EEQQPALK;AVS(1)EEQQPALK 174.72 9.287700000000001e-05 21401400.0 81400.0 68361.0 85002.0 76170.0 71417.0 59889.0 55180.0 66503.0 76684.0 156816.0 True False 80239.22107306817 68202.71430458732 78013.46367720886 81771.79589567111 67216.39247122427 57327.687078077724 58036.950402186405 69592.97216113743 68047.04040168105 183921.43665581488 0.43626899904672595 0.3708252585707008 0.42416732435165205 0.44460176792059547 0.36546252407222674 0.31169660329132304 0.31555294182915195 0.3783842352828705 0.36997884335267706 1.0 17.488730114897216 -11.23434607252264 4.147311982159919 1.0395330308845 0.378279592601891 0.9492285702393332 0.043039250732857505 0.01630056941012071 0.0011340462433404703 0.04317774590717917 0.011254966583921337 5.829803645637862e-12 11.23434607252264 -0.6612534382826092 AVS(ph)GGSPER ddPTM_PC-9_AZD4547_30min_R2 2 AVSGGSPER 9 0 Q96HB5-2;Q96HB5;Q96HB5-5;Q96HB5-3;Q96HB5-4 Q96HB5-2 CCDC120 Coiled-coil domain-containing protein 120 1 AVS(0.876)GGS(0.124)PER;AVS(0.601)GGS(0.399)PER 77.288 0.023277000000000003 7693400.0 25087.0 21986.4 34718.0 49428.0 36571.0 41219.0 28369.0 31984.0 35924.0 37429.0 True False 33064.144157983916 29093.073832514325 34257.61663566177 38033.13825498746 31493.747911410355 38641.56941397773 30893.786041964908 27041.607719203035 37822.86929970046 36118.622102500965 0.915432046774964 0.8054868136982399 0.9484751809867538 1.0530063452324758 0.8719531941731972 1.0698517043179803 0.8553423204875173 0.7486887966673178 1.047184723502547 1.0 15.140455235717988 -5.286461269308349 23.838649947799606 0.9422267667639727 0.8604594233472248 0.1100116799236236 0.09946929689412606 905.9683943300499 863125.6521355629 0.026270581643046322 0.054734303995435725 5.170573674574001e-06 5.286461269308349 -0.08176734341674785 AVS(ph)ILPLLGHGVPR ddPTM_PC-9_AZD4547_30min_R2 1 AVSILPLLGHGVPR 14 0 Q9Y2W2 Q9Y2W2 WBP11 WW domain-binding protein 11 1 AVS(1)ILPLLGHGVPR 97.904 0.0014655 3780600.0 6754.1 7444.8 12699.0 16855.0 10937.0 11350.0 12894.0 14736.0 12544.0 12944.0 True False 8901.763305992714 9851.186009001138 12530.602962620802 12969.340157154116 9418.586336362001 10640.282705758204 14041.541021012212 12458.889799592804 13207.050230916439 12490.834499846967 0.7126636179593745 0.7886731674430424 1.0031838115199045 1.0383085419403333 0.7540397990604546 0.851847224930293 1.124147551645508 0.997442548754084 1.057339301956026 1.0 13.608582244691743 -3.887345268511458 0.6400423052673314 0.9897350954153972 7.393916942474993e-154 0.42573020237267645 0.10297393819941347 10.34776807397576 1.369713119767724 0.04972227403788917 9.729682022218546 0.0001296148410152955 3.887345268511458 -0.9897350954153972 AVS(ph)ILPLLGHGVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVSILPLLGHGVPR 14 0 Q9Y2W2 Q9Y2W2 WBP11 WW domain-binding protein 11 1 AVS(1)ILPLLGHGVPR 118.2 6.746600000000001e-05 6560800.0 5086.0 4296.0 6868.7 4772.0 6172.7 7883.0 6239.3 9577.6 8519.0 4838.1 True False 5946.959346921104 4722.478488725092 7032.47585768981 4504.640311032739 4963.203746097712 7469.601602771615 5648.268335379795 9326.198148306019 8643.5742586354 5715.209231621476 1.0405497167133246 0.8263001925802227 1.2304844097010617 0.7881846715443377 0.868420305355923 1.3069690539837675 0.9882872361222917 1.6318209483399895 1.5123810709871617 1.0 12.480590600581664 -7.28601836630871 1.5282656708344935 1.394941677602976 0.9635992363341573 0.3234296706522256 0.22687726687688448 0.415964211782952 1.891795376174162 0.12949656818766855 0.07580748997085592 5.175849428263686e-08 7.28601836630871 -0.4313424412688186 AVS(ph)ILPLLGHGVPR ddPTM_PC-9_Lapatinib_30min_R1 1 AVSILPLLGHGVPR 14 0 Q9Y2W2 Q9Y2W2 WBP11 WW domain-binding protein 11 1 AVS(1)ILPLLGHGVPR 126.77 1.7492e-05 1929400.0 7980.6 5750.7 7111.9 6096.1 6072.3 8296.4 7851.1 5415.2 9982.5 7312.2 True False 7866.795180537205 5737.384607471956 6527.187034727901 6544.427529993453 5715.139252601132 7941.5823118529925 8257.591542272668 5666.80996115953 8858.165729614808 8576.104027105946 0.9172924157255002 0.6689966200664276 0.7610900024180952 0.7631002969773801 0.6664027435462134 0.9260128243258872 0.962860468596629 0.6607674001211744 1.0328892585278078 1.0 13.066106690280492 -6.775700504560285 24.996658881672776 0.8982011341085409 0.751324058433731 0.32425633382467545 0.11471792174864716 308.5243913566212 540772.9946030709 0.038818634150447125 0.034393402049502975 1.676098338004365e-07 6.775700504560285 -0.1468770756748099 AVS(ph)LDSPVSVGSSPPVK ddPTM_PC-9_AZD4547_30min_R2 2 AVSLDSPVSVGSSPPVK 17 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 AVS(0.999)LDS(0.001)PVSVGSSPPVK;AVS(1)LDSPVSVGSSPPVK 209.66 1.2889e-17 7582800.0 27768.0 24397.0 31150.0 48439.0 38040.0 31452.0 35540.0 44184.0 33197.0 28011.0 True False 36597.646389719666 32282.853140662053 30736.93064695155 37272.1369250898 32758.802618196085 29485.301467974183 38702.99114989713 37356.378047313236 34951.725646981286 27030.343415884832 1.3539467785012471 1.19431901563228 1.1371269012027603 1.3788998664066623 1.2119269856906378 1.0908223034505233 1.4318349772482974 1.382016405509674 1.2930551828076784 1.0 14.722292220731962 -7.267674300187254 24.99230795033022 1.308561326337466 1.2283362878462458 0.009091893728232159 0.13533131999832235 1480.8435579116556 5935841.160887736 0.05393853252615543 0.03739724860910093 5.399153810895731e-08 7.267674300187254 -0.0802250384912202 AVS(ph)LDSPVSVGSSPPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AVSLDSPVSVGSSPPVK 17 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 AVS(1)LDSPVSVGSSPPVK;AVS(0.775)LDS(0.027)PVS(0.001)VGS(0.15)S(0.046)PPVK;AVS(0.987)LDS(0.013)PVSVGSSPPVK 145.1 3.8141e-09 10171300.0 84443.1 127412.4 84870.9 96653.0 109464.0 92478.0 122267.0 121802.0 105948.0 90393.8 True False 98737.64900275129 140061.06103278336 86894.54413068041 91237.84576325376 88015.31499389894 87628.29088178523 110684.98462357665 118604.82655988663 107497.28906607607 106781.48038307314 0.9246701642319903 1.3116606037893594 0.8137604369123808 0.854435108372188 0.8242563661615148 0.8206319163905874 1.0365560041544646 1.1107246887231552 1.0067034909090509 1.0 16.70430192973668 -9.56073106090399 11.977276964598374 0.9999998295038232 0.9671241536395748 0.004313687533068822 0.150202049581259 0.0 0.0 0.15439545769706928 0.03744639883532941 2.7495963277034937e-10 9.56073106090399 -0.03287567586424833 AVS(ph)MDNSNK ddPTM_PC-9_AZD4547_30min_R2 1 AVSMDNSNK 9 0 O43524;O43524-2 O43524 FOXO3 Forkhead box protein O3 1 AVS(0.999)MDNS(0.001)NK 71.03 0.031769 44217000.0 48907.0 45618.0 52035.0 58884.0 56234.0 61805.0 53568.0 59436.0 59618.0 62970.0 True False 64458.40867120504 60363.126391389145 51344.98190093501 45309.20354873114 48426.87976949629 57940.32357968155 58335.44822503347 50251.531903406445 62769.28576744074 60765.439466576274 1.0607741709275396 0.9933792451972898 0.8449701401267256 0.7456410082190427 0.7969477419172333 0.953507850651707 0.9600103074564381 0.8269755364979636 1.0329767433339583 1.0 15.890963399162437 -10.285821224952967 10.969915875420527 0.9999999953448614 0.9049130351919503 0.058790031314672975 0.10030350456916395 0.0 0.0 0.10348596733285084 0.025099033582560146 5.178199459504204e-11 10.285821224952967 -0.09508696015291107 AVS(ph)MDNSNK ddPTM_PC-9_Lapatinib_30min_R1 2 AVSMDNSNK 9 0 O43524;O43524-2 O43524 FOXO3 Forkhead box protein O3 1 AVS(1)MDNSNK;AVS(0.991)MDNS(0.009)NK 109.39 0.002372 54947000.0 62693.0 91735.0 120775.0 147267.0 298210.0 342900.0 359890.0 356010.0 353700.0 366650.0 True False 61798.98632351188 91522.59324368162 110845.34570498209 158097.50644831025 280669.8741034179 328234.96633894154 378523.34324470535 372551.52427840244 313862.58137388 430024.9639695842 0.14371022964118646 0.21283088404643188 0.2577649089991487 0.36764727561140503 0.6526827454679347 0.7632928174889811 0.880235742014918 0.8663485971590085 0.7298706067587266 1.0 18.7140608885532 -6.274284174270439 1.1670716084810873 0.8644292233467419 0.17008430095837504 0.9539253060207264 0.06379896280920169 0.08948453074633742 0.2516713114450158 0.026043416105851404 0.03788719553740279 5.317601958629403e-07 6.274284174270439 -0.6943449223883669 down AVS(ph)MDNSNKYTK ddPTM_PC-9_AZD4547_30min_R2 1 AVSMDNSNKYTK 12 1 O43524;O43524-2 O43524 FOXO3 Forkhead box protein O3 1 AVS(0.99)MDNSNKY(0.008)T(0.002)K 58.723 0.031651 34258000.0 124180.0 66178.0 159640.0 315030.0 259890.0 181000.0 136430.0 208010.0 135770.0 215720.0 True False 163666.65689554115 87568.74431867577 157523.06929307707 242404.7006649812 223808.75952794362 169682.04138698088 148572.00570006945 175866.83409427875 142946.5250200514 208167.70846005747 0.7862250014965456 0.4206644006722982 0.7567123184396396 1.164468314793853 1.075136778819311 0.8151218200085961 0.7137130287840823 0.844832444932368 0.68668923762246 1.0 17.667386765659685 -5.520677819984079 24.99525556227649 0.8949949898402835 0.5997555794294059 0.34624388270010265 0.16373390754929196 90.92608263869343 1032619.3649154787 0.04691256487782201 0.08298863429445055 3.0152420426597732e-06 5.520677819984079 -0.29523941041087753 AVS(ph)MDNSNKYTK ddPTM_PC-9_Lapatinib_30min_R1 1 AVSMDNSNKYTK 12 1 O43524;O43524-2 O43524 FOXO3 Forkhead box protein O3 1 AVS(0.999)MDNS(0.001)NKYTK 143.56 0.00041411 11701000.0 16432.0 7808.2 11082.0 13300.0 19790.0 24562.0 16891.0 15384.0 34981.0 21689.0 True False 16197.676666740253 7790.120592634374 10170.880737757085 14278.126367499375 18625.991108637 23511.54051681854 17765.533331702267 16098.796802053148 31041.07141373958 25437.914751224118 0.6367533198042812 0.30624053381810706 0.39983154426082207 0.561293113336355 0.7322137561507743 0.9242715350984939 0.6983879577176174 0.6328662140546896 1.2202679235822909 1.0 14.634692791470103 -6.711993411962039 0.4844258614630219 1.009561910164101 0.368617005762774 0.589558467835138 0.167511173107859 0.8413369985501703 0.41653173679965705 0.15840256045466952 0.22836119476573674 1.9409153201193492e-07 6.711993411962039 -0.6409449044013269 AVS(ph)PAPQSSSR ddPTM_PC-9_AZD4547_30min_R2 2 AVSPAPQSSSR 11 0 A0A075B784;Q9P275 A0A075B784 USP36 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 36 1 AVS(0.862)PAPQS(0.059)S(0.019)S(0.059)R;AVS(1)PAPQSSSR 104.94 0.005746500000000001 0.0 57314.0 60709.0 82977.0 115276.0 102315.0 91830.0 78322.0 111903.0 86394.0 99426.0 True False 75538.65979474207 80331.99702079984 81876.67076379141 88700.89919644601 88110.32833545582 86087.85558324026 85292.50627018145 94610.96262512424 90960.6104631534 95945.12600291893 0.7873110697925808 0.8372702227558272 0.853369776817016 0.9244961457838669 0.9183408475879771 0.8972613739714221 0.888971746908609 0.9860945163826863 0.9480482673021463 1.0 16.54992189915385 -1.5228787452804278 0.19099003655087832 0.9998580478709228 0.058499265479360046 0.8314234756390874 0.025780160768596187 22.754515203188372 0.26686914322044214 0.05547653904022726 6.322197994478829 0.029999999999993768 1.5228787452804278 -0.9413587823915628 AVS(ph)PAPQSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVSPAPQSSSR 11 0 A0A075B784;Q9P275 A0A075B784 USP36 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 36 1 AVS(0.999)PAPQS(0.001)SSR 96.756 0.013992 0.0 58724.0 71498.0 92714.0 103810.0 123190.0 103680.0 111930.0 105320.0 98757.0 81055.0 True False 68664.81334813111 78595.84892617943 94924.65337980317 97993.862256561 99051.80382681447 98242.83828179122 101327.18009697575 102555.46159576417 100201.13429511184 95749.62986897296 0.7171287601016774 0.8208475482749401 0.9913840242484623 1.0234385489600233 1.0344875897939274 1.0260388308156392 1.0582514024924723 1.0710794572898563 1.0464910875606566 1.0 16.54697928969692 -5.106017003697707 1.5580066248532034 1.042782538398776 0.679868477901908 0.9710861123830747 0.018686227334851428 0.08972508290126276 0.31527059914607486 0.005581851190695243 0.04133233457737784 7.833989701682407e-06 5.106017003697707 -0.36291406049686814 AVS(ph)PAPQSSSR ddPTM_PC-9_Lapatinib_30min_R1 1 AVSPAPQSSSR 11 0 A0A075B784;Q9P275 A0A075B784 USP36 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 36 1 AVS(1)PAPQSSSR 106.79 0.004666399999999999 0.0 56093.0 47740.0 58578.0 56602.0 60549.0 52232.0 48785.0 47501.0 59134.0 43631.0 True False 55293.103533803645 47629.460963136844 53761.94295761907 60764.69989873686 56987.62686391419 49998.159118738935 51310.848593161725 49708.06987092604 52473.70621137409 51172.56021534691 1.0805225163860566 0.9307617356391821 1.0506010004458521 1.1874469372457392 1.113636422021803 0.9770501790087148 1.0027023931816752 0.9713813352652686 1.0254266347150043 1.0 15.643082794206482 -6.774276202275754 24.99933063444462 0.9939853237546115 1.0698730867766324 0.28429087166475986 0.06121609256391829 359.2791709220539 699681.5220663367 0.024012660407076798 0.02131589030434762 1.6816042555183466e-07 6.774276202275754 0.07588776302202094 AVS(ph)PAVPFSR ddPTM_PC-9_AZD4547_30min_R2 2 AVSPAVPFSR 10 0 I3L2J0 I3L2J0 CIC 1 AVS(0.998)PAVPFS(0.002)R;AVS(0.999)PAVPFS(0.001)R 96.756 0.0054084 71044000.0 187230.0 190896.0 237896.0 393260.0 315960.0 286470.0 251600.0 357790.0 272070.0 297060.0 True False 246765.24537407112 252599.398825258 234741.34360151476 302599.9828064331 272094.4078665945 268556.9856139694 273991.9125862161 302501.7766962743 286451.06475808675 286660.0198180268 0.8608289552575867 0.8811811252424016 0.8188841393038685 1.0556058113668068 0.9491885476018643 0.9368484164078782 0.9558079035930701 1.0552632239692996 0.9992710700987438 1.0 18.128981181832444 -5.753925416138134 24.999812913271032 0.9897109609609724 0.8563863611866499 0.7123305656590954 0.04057509722865327 100.55275723358082 334546.74478789314 0.01168709696920934 0.019749299779535025 1.7622786665656939e-06 5.753925416138134 -0.13332459977432254 AVS(ph)PAVPFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AVSPAVPFSR 10 0 I3L2J0 I3L2J0 CIC 1 AVS(0.654)PAVPFS(0.346)R;AVS(1)PAVPFSR;AVS(0.996)PAVPFS(0.004)R;AVS(0.999)PAVPFS(0.001)R 96.756 0.0054084 61560300.0 165556.0 151587.0 176235.0 195681.0 253446.0 209213.0 181375.0 170568.0 169441.0 158016.0 True False 193581.3609199506 166635.5555564177 180437.11077495958 184717.62797636172 203785.07567733407 198241.5019815623 164193.8469587149 166090.77073173458 171918.75407412185 186663.0499460323 1.037063098325665 0.8927077726662834 0.9666461081993852 0.9895778946597464 1.0917269150817586 1.0620286234414231 0.8796269374479113 0.8897892259863667 0.9210111702547811 1.0 17.51007684798158 -10.534163096940556 4.8633006011250925 1.0000004742753337 0.9694893151665346 0.015518857175938816 0.07152362713065188 110669744.59762727 18.017602215563155 587.7705551019637 0.01898429724176072 2.923054434431189e-11 10.534163096940556 -0.03051115910879909 AVS(ph)PAVPFSR ddPTM_PC-9_Lapatinib_30min_R1 2 AVSPAVPFSR 10 0 I3L2J0 I3L2J0 CIC 1 AVS(0.999)PAVPFS(0.001)R;AVS(0.997)PAVPFS(0.003)R 86.11399999999999 0.011473 57971000.0 348410.0 309140.0 370930.0 314230.0 326540.0 307900.0 289350.0 267180.0 322930.0 261020.0 True False 343441.60950943176 308424.2053235055 340433.5672312075 337339.5224405507 307333.55920234043 294731.834749956 304331.12719957664 279594.15818854317 286558.2227963448 306136.95921271155 1.1218560816461236 1.0074713164874833 1.1120302759480465 1.101923542025381 1.0039087080263231 0.9627450259776343 0.9941012283594279 0.9132976263551185 0.9360458258071251 1.0 18.223817703078623 -6.473889310074588 3.031335451192696 0.9581394202283071 1.0818742498839087 0.7069855756379264 0.03771205534346523 0.14797990218957227 2.709242749858578 0.012841069093111213 0.014110527234928734 3.358231955922987e-07 6.473889310074588 0.12373482965560156 AVS(ph)PEEGAR ddPTM_PC-9_Lapatinib_30min_R1 1 AVSPEEGAR 9 0 B4DKV7;Q8TE68-2;Q8TE68;K7ELW3;Q8TE68-4 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 AVS(1)PEEGAR 70.41199999999999 0.037743 3993500.0 21237.0 19822.0 25828.0 20542.0 23989.0 16735.0 15505.0 17786.0 18557.0 13843.0 True False 20934.156485611187 19776.103376860054 23704.521538963185 22052.727206103173 22578.014184188614 16019.28306119038 16307.773033452348 18612.40249098526 16466.915246126915 16235.744105361951 1.2893869446179285 1.218059563425176 1.4600206424252908 1.3582825069791613 1.3906362429506443 0.9866676240542567 1.0044364414481384 1.1463843215438707 1.0142384075078283 1.0 13.986885886287086 -6.760960826210745 24.999997694034686 1.037875045066274 1.3436400494564 0.824113385168854 0.07224210833434812 5.605306352018678 292831.66084441164 0.02592115183455906 0.024434758317682083 1.7339603956328827e-07 6.760960826210745 0.3057650043901261 AVS(ph)PPHLDGPPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 AVSPPHLDGPPSPR 14 0 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BVD2;H3BT57;H3BUJ5;H3BRN3;P29590-2 P29590;P29590-2 PML Protein PML 2 AVS(1)PPHLDGPPS(1)PR;AVS(1)PPHLDGPPS(1)PR 116.73 0.00031306 42162000.0 151140.0 168095.0 194005.0 213290.0 179556.0 197360.0 173701.0 211617.0 173698.0 167217.0 True False 199199.3760927055 222428.42147311504 191432.36693938504 164119.28579765078 154627.74876216624 185019.04800074367 189160.0524965749 178916.45512489363 182879.32166850485 161362.78372689383 1.2344815297054494 1.3784369377859438 1.1863476975173155 1.0170826383078662 0.9582615346043694 1.1466029757759262 1.1722656744489974 1.1087838905141185 1.1333426298472127 1.0 17.29994835216135 -5.510492951345689 5.11593210242816 1.0836563394233696 1.3035620720868124 0.6169018588363393 0.07253951900259964 0.12069301172914458 9.34978933010089 0.020775643317308478 0.040871433131979655 3.0867897442648493e-06 5.510492951345689 0.21990573266344282 AVS(ph)PPHLDGPPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 AVSPPHLDGPPSPR 14 0 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BVD2;H3BT57;H3BUJ5;H3BRN3;P29590-2 P29590;P29590-2 PML Protein PML 2 AVS(1)PPHLDGPPS(1)PR;AVS(1)PPHLDGPPS(1)PR;AVS(1)PPHLDGPPS(1)PR;AVS(1)PPHLDGPPS(1)PR;AVS(1)PPHLDGPPS(1)PR;AVS(1)PPHLDGPPS(1)PR;AVS(1)PPHLDGPPS(1)PR;AVS(1)PPHLDGPPS(1)PR 148.97 0.0026594 60179500.0 147165.3 203318.4 190339.9 161761.6 202154.7 158810.6 154011.2 126389.8 137616.2 128689.9 True False 172077.47864283252 223502.50706750603 194878.3250840906 152698.621990183 162543.93771465612 150482.29256591666 139422.14419147058 123072.20167106276 139628.57658072794 152020.36016131216 1.1319370540908948 1.470214297810784 1.2819225324640786 1.0044616512429725 1.0692247902989913 0.9898824894654675 0.917128100759179 0.8095770957289414 0.9184860266911944 1.0 17.21390503189952 -5.998776208687928 1.1980070270009866 0.9159431307877636 1.3294542027799345 0.6860820422822076 0.10293550886770565 0.2622061027587301 0.7651957526858361 0.03948673707356641 0.07673885619414846 1.002821857598043e-06 5.998776208687928 0.41351107199217096 AVS(ph)PPHLDGPPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 8 AVSPPHLDGPPSPR 14 0 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BVD2;H3BT57;H3BUJ5;H3BRN3;P29590-2 P29590;P29590-2 PML Protein PML 2 AVS(1)PPHLDGPPS(1)PR;AVS(1)PPHLDGPPS(1)PR;AVS(1)PPHLDGPPS(1)PR;AVS(1)PPHLDGPPS(1)PR;AVS(1)PPHLDGPPS(1)PR;AVS(1)PPHLDGPPS(1)PR;AVS(1)PPHLDGPPS(1)PR;AVS(1)PPHLDGPPS(1)PR 130.87 0.00021961 63583800.0 210468.7 214609.0 224542.5 171737.6 207531.1 214032.2 182756.1 192721.9 208847.0 154865.5 True False 207467.37774276757 214112.08604603715 206081.4824091155 184367.75600383928 195324.52871984095 204878.54173942725 192218.3166255352 201676.46303988548 185324.45160359278 181633.79532969257 1.1422289412946702 1.1788119367180079 1.1345987790160235 1.0150520483767032 1.0753754738499939 1.1279758888897409 1.058273964251147 1.11034657770495 1.0203192157450716 1.0 17.47067313421539 -1.5228787452803376 0.13218066979645227 0.9889584184979335 1.5632708984612051 0.5090006697760096 0.04092827750141964 75.8389298180791 0.6786260340120488 0.22392187903910513 8.136946120135097 0.029999999999999995 1.5228787452803376 0.5743124799632716 AVS(ph)PSNPK ddPTM_PC-9_AZD4547_30min_R2 3 AVSPSNPK 8 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 AVS(0.976)PS(0.024)NPK;AVS(0.697)PS(0.303)NPK;AVS(0.792)PS(0.208)NPK 79.986 0.019938 67788000.0 282031.0 299845.0 372859.0 520829.0 523207.0 468675.0 451102.0 529433.0 404196.0 526732.0 True False 371710.99139077467 396764.03246144217 367914.6460382576 400759.92077783647 450568.739260213 439368.67816046 491249.204099631 447621.2950100297 425560.9753775119 508291.27300474275 0.7312952457228324 0.780583994912972 0.7238264073733657 0.7884454092803145 0.8864380783024163 0.8644033480314355 0.9664718443730732 0.8806393475220123 0.8372384063606402 1.0 18.9552959354005 -6.224906481198046 2.1707801119255743 0.9053687126490699 0.7473620486196608 0.7195966320428511 0.046513028945948554 0.17458427911574037 1.6151879952805959 0.015220327205371987 0.020119879286831628 5.957904242474357e-07 6.224906481198046 -0.1580066640294091 AVS(ph)PSNPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AVSPSNPK 8 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 AVS(0.869)PS(0.131)NPK;AVS(0.5)PS(0.5)NPK 87.149 0.011942 42629000.0 192069.0 220681.0 332270.0 306970.0 367040.0 301570.0 329030.0 318960.0 272340.0 228890.0 True False 224582.48816433124 242588.75125007983 340192.576940993 289771.46611016785 295121.1468186865 285755.1383163562 297861.8964290892 310587.6379660545 276322.4572833396 270385.94510775676 0.8305997121071825 0.8971943832117497 1.2581740400944887 1.0716957421536293 1.091481092706472 1.056841686806148 1.1016175279021343 1.1486826278720819 1.02195569807897 1.0 18.04466063548614 -5.086440399073969 6.873108121511234 1.096915611068977 0.8463931190461825 0.6509434501204185 0.06805928067839309 0.12198117311017408 8.136200141875253 0.01651790967177396 0.04500743812719874 8.195200832884767e-06 5.086440399073969 -0.25052249202279453 AVS(ph)PSNPK ddPTM_PC-9_Lapatinib_30min_R1 4 AVSPSNPK 8 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 AVS(0.845)PS(0.155)NPK;AVS(0.5)PS(0.5)NPK;AVS(0.849)PS(0.151)NPK;AVS(0.5)PS(0.5)NPK 89.029 0.010532 117596000.0 470989.0 436420.0 526760.0 469073.0 457345.0 392990.0 377051.0 340763.0 436294.0 292781.0 True False 464272.61049119616 435409.49630356487 483451.82615240174 503570.19320165785 430444.86627486575 376182.73380443425 396572.85585528763 356596.09299649164 387153.9753405017 343387.8057438397 1.352035811188747 1.2679818241081382 1.4078887428898594 1.4664766330616612 1.2535240304833912 1.095504055508188 1.1548833395415412 1.0384646368674637 1.1274540588354807 1.0 18.389479282253106 -6.6136729308537765 3.2451226901252666 1.0888291607563458 1.368731125553929 0.8285172852015477 0.06231466547958462 0.10394334567266289 2.1877371221140876 0.02236951456096416 0.02252601432555931 2.434036402861839e-07 6.6136729308537765 0.2799019647975831 AVS(ph)PSSSEK ddPTM_PC-9_AZD4547_30min_R2 2 AVSPSSSEK 9 0 Q76FK4-2;Q76FK4-4;Q76FK4;F8WE42;F5H101 Q76FK4-2 NOL8 Nucleolar protein 8 1 AVS(0.926)PS(0.036)S(0.011)S(0.027)EK;AVS(0.929)PS(0.016)S(0.051)S(0.003)EK 110.84 0.0022751 25143000.0 88388.0 85109.0 83095.0 102650.0 83862.0 94258.0 94543.0 100215.0 100947.0 102158.0 True False 116493.54541539004 112618.81985279359 81993.1060066914 78985.6284266906 72219.20886349004 88364.03235941479 102957.14384594036 84729.07446160373 106282.85233261508 98581.47951447517 1.1816980835460555 1.1423932812476938 0.8317293107236434 0.8012217793413496 0.7325839419247686 0.8963553072505865 1.0443862716710666 0.8594826825373681 1.0781219033845915 1.0 16.589029012741378 -5.22308525208016 7.8988893557524795 0.8952403307689288 1.1638723564611921 0.4917037632724406 0.10393537639837416 0.24657672297908084 45.20695384752611 0.027943082064430337 0.07351775775196243 5.982941382918932e-06 5.22308525208016 0.2686320256922633 AVS(ph)PSSSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AVSPSSSEK 9 0 Q76FK4-2;Q76FK4-4;Q76FK4;F8WE42;F5H101 Q76FK4-2 NOL8 Nucleolar protein 8 1 AVS(0.761)PS(0.077)S(0.137)S(0.025)EK;AVS(0.846)PS(0.022)S(0.022)S(0.109)EK;AVS(0.952)PS(0.024)S(0.024)S(0.001)EK 88.134 0.010353 23079000.0 113099.0 194166.0 157282.0 132458.0 170738.0 135111.0 134808.0 120480.0 118973.0 112146.0 True False 132244.4268929273 213441.51728160994 161032.19937530626 125036.80769462994 137283.11455298823 128025.541310678 122038.010314599 117317.52765911166 120712.75505019716 132477.18205275232 0.9982430547191716 1.6111568345152274 1.2155466841918734 0.9438365593015133 1.0362774360517586 0.9663969245639473 0.9212002280211814 0.8855678075368172 0.9111965787597249 1.0 17.01538436487342 -5.668282592515924 4.1455676954320815 0.9495618697894583 1.3273712972752616 0.51568076857384 0.14411180514575472 0.1490129376928634 4.693540171009608 0.03775127226331278 0.06737124488280047 2.146433349799239e-06 5.668282592515924 0.37780942748580326 AVS(ph)PSSSEK ddPTM_PC-9_Lapatinib_30min_R1 1 AVSPSSSEK 9 0 Q76FK4-2;Q76FK4-4;Q76FK4;F8WE42;F5H101 Q76FK4-2 NOL8 Nucleolar protein 8 1 AVS(0.96)PS(0.03)S(0.009)S(0.002)EK 110.54 0.0022949999999999997 11143000.0 18633.0 40388.0 38440.0 34315.0 43233.0 39547.0 44271.0 47893.0 46027.0 31458.0 True False 18367.29000312628 40294.4840674313 35279.61158269106 36838.6395714843 40690.1199393483 37855.666998559675 46563.13576033335 50118.28362199242 40842.95457420291 36895.47338484984 0.49781960544429077 1.0921254118934052 0.9562043347349408 0.9984595992908746 1.1028485666769254 1.0260246996615068 1.262028414018216 1.3583857049133885 1.1069909348547347 1.0 15.171156205975505 -4.5625207707937525 2.1642988717291707 1.1153055086155343 1.0456993531239529e-41 0.686581218210291 0.12089432701285216 1.0114837875852252 3.040029029179874 0.035249063089335966 2.7343185405937467 2.7382886683146268e-05 4.5625207707937525 -1.1153055086155343 AVS(ph)PSSSEKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVSPSSSEKR 10 1 Q76FK4-2;Q76FK4-4;Q76FK4;F8WE42;F5H101 Q76FK4-2 NOL8 Nucleolar protein 8 1 AVS(0.761)PS(0.152)S(0.043)S(0.043)EKR 77.67399999999999 0.031499 10865000.0 12800.0 10983.0 16706.0 16077.0 18794.0 18684.0 15076.0 17387.0 15115.0 12874.0 True False 14966.787188476233 12073.319655881678 17104.334397857805 15176.257812337259 15111.450613857849 17704.178148697814 13647.892139212052 16930.609673049294 15336.028280229373 15207.954289472065 0.9841420419600562 0.7938819006208886 1.1246965944458773 0.997915796133294 0.9936543946820631 1.1641393583720723 0.8974180142466637 1.1132733141346802 1.0084215133948666 1.0 13.892538480348508 -5.26341568079914 24.999992782349782 1.0380342075374835 0.8890119735904074 0.3260689140590518 0.08535148455068477 175.618571305818 2221588.440792749 0.02052739617103451 0.046563660026352545 5.452357440970004e-06 5.26341568079914 -0.14902223394707614 AVS(ph)PTEPTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVSPTEPTPR 10 0 Q6PJI9-3;Q6PJI9;H3BMH3;Q6PJI9-2 Q6PJI9-3 WDR59 WD repeat-containing protein 59 1 AVS(0.668)PT(0.314)EPT(0.018)PR 75.566 0.024332 4132200.0 28011.0 28649.0 32813.0 39829.0 38168.0 35747.0 40106.0 35536.0 35390.0 24172.0 True False 32752.70905753183 31493.08338535502 33595.38636399547 37597.51025736024 30689.254391280527 33872.364391003015 36306.869337704884 34603.21765350432 35907.51179869783 28554.19225455328 1.1470367911496095 1.1029232802175695 1.1765483003161583 1.3167071903904024 1.0747722827420128 1.186248383040907 1.271507490530234 1.2118436881360724 1.257521539344962 1.0 14.801414953538469 -5.510077609505933 24.581218117685143 1.1997472627701735 1.1286689506106553 0.06311075894511653 0.08888953649271704 1099.2600542385255 2110833.319715442 0.022629441229523612 0.043734873887835146 3.089743238361234e-06 5.510077609505933 -0.07107831215951821 AVS(ph)PTEPTPR ddPTM_PC-9_Lapatinib_30min_R1 1 AVSPTEPTPR 10 0 Q6PJI9-3;Q6PJI9;H3BMH3;Q6PJI9-2 Q6PJI9-3 WDR59 WD repeat-containing protein 59 1 AVS(0.608)PT(0.385)EPT(0.008)PR 97.47200000000001 0.0051321000000000006 15497000.0 48485.0 44936.0 59940.0 47607.0 43818.0 43159.0 45064.0 37627.0 47568.0 37106.0 True False 47793.595008939956 44831.95345285963 55011.96457509109 51108.17759229645 41240.71138950257 41313.19017854291 47397.193420154545 39375.28778411685 42210.39092675351 43519.72265936288 1.0982054132796177 1.0301525541366112 1.264069741567063 1.174368182268298 0.9476326793785299 0.949298103342916 1.0890968628440343 0.9047688123454898 0.9699140607384437 1.0 15.409381742221417 -6.262121756305445 24.99971380288413 0.9762647634397296 1.1424721446819945 0.5644059259134029 0.07097324574357333 48.66032981113218 1782726.035136753 0.022536422146114787 0.027092832692565055 5.468626261371352e-07 6.262121756305445 0.16620738124226497 AVS(ph)T(ph)VVVT(ph)T(ph)APSPK ddPTM_PC-9_Lapatinib_30min_R1 1 AVSTVVVTTAPSPK 14 0 Q6P4R8-3;Q6P4R8;Q6P4R8-2 Q6P4R8-3 NFRKB Nuclear factor related to kappa-B-binding protein 4 AVS(0.998)T(0.998)VVVT(0.998)T(0.999)APS(0.008)PK 65.043 0.023563 3441200.0 15165.0 13581.0 18103.0 13308.0 15600.0 11792.0 11056.0 12080.0 14593.0 12984.0 True False 14948.744319079595 13549.55402891416 16614.64121960082 14286.714714186588 14682.438670780039 11287.683648494592 11628.42558257653 12641.280900208143 12949.38266889745 15228.267099907507 0.9816444787188157 0.8897633552143603 1.0910395195065716 0.9381707465765007 0.9641568915526322 0.741232313200177 0.7636079342637192 0.8301194625280064 0.8503516903099303 1.0 13.894464159285965 -6.690221402596894 8.84391813337616 0.8220113506051048 0.9735436204425256 0.41054101328537085 0.08043100017492702 0.26711706312018535 30.292791417906454 0.02584288353153256 0.025804473258334855 2.0406973353701493e-07 6.690221402596894 0.15153226983742085 AVSETPAVPPVS(ph)EDEDDDDDDATPPPVIAPRPEHTK ddPTM_PC-9_Lapatinib_30min_R1 1 AVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTK 36 1 H0YCM0;E9PM17;B3KNX7;Q13153;Q13153-2 H0YCM0 PAK1 Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase PAK 1 1 AVSET(0.002)PAVPPVS(0.998)EDEDDDDDDATPPPVIAPRPEHTK 100.14 7.2471e-17 5953400.0 35738.0 34012.0 39886.0 30169.0 38436.0 35544.0 29084.0 29649.0 43088.0 28864.0 True False 35228.369566453446 33933.24730369105 36606.72704441245 32387.72890083374 36175.27004808345 34023.86597711088 30589.827210895062 31026.600778995948 38234.97570324497 33853.103941137546 1.0406245060336907 1.002367385947618 1.0813403435047728 0.9567137169208548 1.0685953675321351 1.005044206175902 0.9036047998459302 0.9165068240993142 1.1294378137297676 1.0 15.047000497993373 -7.003558465347053 24.938625379508583 0.9767002960836663 1.028149251869269 0.07650686351679503 0.06574677472771208 321.3311414375591 2251981.4516003495 0.02309777532989139 0.019947178133840334 9.918398073514314e-08 7.003558465347053 0.05144895578560271 AVSGGS(ph)PER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVSGGSPER 9 0 Q96HB5-2;Q96HB5;Q96HB5-5;Q96HB5-3;Q96HB5-4 Q96HB5-2 CCDC120 Coiled-coil domain-containing protein 120 1 AVS(0.227)GGS(0.773)PER 84.81700000000001 0.012915000000000001 2673200.0 13207.0 14699.0 17079.0 16272.0 25941.0 24873.0 12819.0 17213.0 19332.0 16898.0 True False 15442.684249859816 16158.21957769324 17486.228132468194 15360.332594535783 20858.047269026643 23568.616093585973 11604.691518477008 16761.176988681054 19614.69392744917 19961.473635505605 0.7736244593881992 0.809470276230133 0.8759988591907024 0.7694989295386618 1.0449152026494826 1.1807052186600253 0.5813544495951274 0.8396763332576729 0.9826275497296144 1.0 14.284930609651424 -6.23169458693627 24.887081413403802 0.9244786497208847 0.8122319035206829 0.1529040895384849 0.14884822720361074 1651.6457670008685 1381910.462153953 0.046780568389062055 0.060384954848946376 5.86550505033574e-07 6.23169458693627 -0.11224674620020181 AVSGGS(ph)PERR ddPTM_PC-9_AZD4547_30min_R2 1 AVSGGSPERR 10 1 Q96HB5-2;Q96HB5;Q96HB5-5;Q96HB5-3;Q96HB5-4 Q96HB5-2 CCDC120 Coiled-coil domain-containing protein 120 1 AVS(0.001)GGS(0.999)PERR 72.73100000000001 0.01366 13251000.0 8566.8 5842.2 9675.9 13435.0 12096.0 9212.8 7470.2 10161.0 6778.0 9584.0 True False 11290.864199490443 7730.576899552233 9547.591243879251 10337.768318680852 10416.679192158248 8636.722159613144 8135.033328305052 8590.850926551466 7136.271242438748 9248.467077142564 1.2208362861987831 0.8358765658211865 1.0323431077000822 1.117781815348673 1.1263141345772751 0.933854452589085 0.8796088325178402 0.9288945784089575 0.7716166563511835 1.0 13.174998545050551 -6.920296971835541 5.766309603358209 0.8913581119992872 1.0541887947856574 0.37355282224187025 0.10628492635452448 0.2375024409959691 13.092202071392018 0.03766616951690076 0.03309835564023302 1.2014426037017514e-07 6.920296971835541 0.16283068278637025 AVSGGS(ph)PERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AVSGGSPERR 10 1 Q96HB5-2;Q96HB5;Q96HB5-5;Q96HB5-3;Q96HB5-4 Q96HB5-2 CCDC120 Coiled-coil domain-containing protein 120 1 AVS(0.002)GGS(0.998)PERR;AVS(0.013)GGS(0.987)PERR;AVS(0.003)GGS(0.997)PERR;AVSGGS(1)PERR 63.943999999999996 0.024276 33284800.0 29741.7 30419.6 45986.3 51073.9 54926.2 45237.6 43204.7 50123.2 44045.4 37200.2 True False 34776.382384648714 33439.45685186728 47082.787796013945 48212.3949668179 44163.80540102584 42865.260619756555 39112.03804105961 48807.51910992028 44689.48064928977 43944.301783378825 0.7913741025190729 0.760950919568716 1.0714196354309171 1.0971250653720344 1.004995041649064 0.975445254109592 0.8900366248589041 1.1106677573468895 1.016957349091226 1.0 15.423388484125654 -5.256343475813933 24.966455771382225 1.0206503561850762 0.7761624816214886 0.7225380850187875 0.060646878992097954 218.7897194963987 1071911.7350606804 0.016585776590500888 0.04111365360378575 5.541872427165558e-06 5.256343475813933 -0.24448787456358756 AVSGGS(ph)PERR ddPTM_PC-9_Lapatinib_30min_R1 2 AVSGGSPERR 10 1 Q96HB5-2;Q96HB5;Q96HB5-5;Q96HB5-3;Q96HB5-4 Q96HB5-2 CCDC120 Coiled-coil domain-containing protein 120 1 AVS(0.001)GGS(0.999)PERR;AVS(0.001)GGS(0.999)PERR 73.082 0.013241 23708000.0 13093.2 12880.4 13384.3 11829.3 14844.4 11939.7 11964.0 12631.3 13442.8 11445.7 True False 12906.488567001183 12850.576225169416 12283.894518892079 12699.266183387997 13971.281577213282 11429.066863800104 12583.437379698407 13218.196310827741 11928.730305040413 13424.07399456341 0.9614434911658083 0.9572784111867787 0.9150645715948011 0.9460068671053995 1.0407631530391954 0.8513858660514491 0.9373784280982471 0.9846635467132372 0.8886073117498762 1.0 13.712534952711536 -6.76191757706789 24.999999999398213 0.9317592336013302 0.9600010588510431 0.08992150817473432 0.04955436905201302 38.82700703688793 2029728.5241942764 0.01680302249922455 0.015710505473629784 1.730144684977086e-07 6.76191757706789 0.02824182524971297 AVSISYT(ph)VMTPMLNPMIYT(ph)LRNQDMK ddPTM_PC-9_Lapatinib_30min_R1 1 AVSISYTVMTPMLNPMIYTLRNQDMK 26 1 Q15615 Q15615 OR4D1 Olfactory receptor 4D1 2 AVS(0.057)IS(0.057)Y(0.293)T(0.32)VMT(0.275)PMLNPMIY(0.477)T(0.521)LRNQDMK 45.395 0.011175 9129000.0 21984.0 18321.0 19808.0 16835.0 21112.0 18631.0 19103.0 20860.0 20158.0 17798.0 True False 21670.504128628145 18278.578850138892 18179.46270109115 18073.102059913694 19870.233667789005 17834.19556098225 20092.059868303135 21829.231753173975 17887.59376684952 20874.36058565572 1.0381397810824209 0.8756473653472971 0.8708991409099052 0.8658038643029395 0.9518966382828166 0.8543588910329265 0.9625233686012802 1.0457437325373413 0.8569169672742637 1.0 14.349444385805269 -7.4464596035951285 10.571647089969582 0.9715856544167807 0.9062442917502408 0.14425446421880805 0.06741620460285089 1.1094699050324341 149.91496271763555 0.027304030480323968 0.018385403994411097 3.5771767255318176e-08 7.4464596035951285 -0.06534136266653989 AVSLDS(ph)PVSVGSSPPVK ddPTM_PC-9_AZD4547_30min_R2 1 AVSLDSPVSVGSSPPVK 17 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 AVSLDS(0.987)PVS(0.01)VGS(0.003)SPPVK 129.29 3.0511e-05 2444000.0 14360.0 14583.0 16969.0 23372.0 21902.0 21867.0 13691.0 18388.0 13604.0 19279.0 True False 18926.181293444773 19296.669563892057 16743.979972652367 17983.94649380042 18861.28535603919 20499.65303319954 14909.472477018624 15546.557114204152 14323.079666883552 18604.048078070904 1.0173152216131702 1.037229611690671 0.900018098340057 0.966668459376784 1.0138269519025538 1.1018920692514784 0.8014101239930047 0.8356545333017764 0.7698904887139351 1.0 14.183328952857488 -7.275820828421869 24.997457725818098 0.8380433217356362 1.0012997454737036 0.5037290241084107 0.07450032162554206 651.0340691183353 1131605.8690355157 0.030796519744179893 0.020867684958819334 5.298820057610038e-08 7.275820828421869 0.16325642373806737 AVSLDS(ph)PVSVGSSPPVK ddPTM_PC-9_Lapatinib_30min_R1 2 AVSLDSPVSVGSSPPVK 17 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 AVSLDS(0.808)PVS(0.191)VGSSPPVK;AVS(0.054)LDS(0.907)PVS(0.037)VGS(0.001)SPPVK 196.22 3.5898e-12 5166900.0 47168.0 37279.0 53278.0 40358.0 36961.0 42065.0 26479.0 33154.0 38616.0 27429.0 True False 46495.37567044819 37192.68276591495 48897.68849902739 43326.06195034136 34787.02664812187 40265.97800830433 27849.953057257942 34694.45587462754 34266.659435492635 32170.066103154873 1.4452993513087142 1.1561270233842484 1.5199747598352638 1.3467818751573046 1.0813476893885012 1.2516597845708344 0.8657101594990735 1.0784701456123247 1.0651721798026443 1.0 14.973431279997538 -6.531975231604868 1.4222949230502029 1.0241788709549922 1.3657186548788613 0.599798539576762 0.1239474354746682 0.28886260287859694 1.202615522492673 0.05082280025510826 0.055988808266006385 2.937817194827572e-07 6.531975231604868 0.3415397839238692 AVSLDSPVSVGS(ph)SPPVK ddPTM_PC-9_AZD4547_30min_R2 1 AVSLDSPVSVGSSPPVK 17 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 AVS(0.001)LDS(0.073)PVS(0.001)VGS(0.924)S(0.001)PPVK 284.53 9.084799999999998e-97 59712000.0 47392.0 41102.0 49196.0 76538.0 61298.0 46460.0 47915.0 69010.0 47705.0 52143.0 True False 62461.67018516259 54387.41770658244 48543.62889590461 58893.34660031226 52787.83078049906 43554.84885546485 52179.34217634557 58346.09019203979 50226.58890831226 50317.48944109395 1.241351086450481 1.0808849628766375 0.964746640484399 1.1704349174506798 1.0490950833764692 0.8656005961198434 1.0370020991892146 1.1595588500166492 0.9981934604887609 1.0 15.618772321217365 -4.796781384906216 3.5962314979120453 1.0355141464713136 1.2613385232425731 0.3606930833678218 0.0839562777823737 0.30766272437260245 6.756528341025903 0.02192612489227092 0.1835779189591727 1.596682682877001e-05 4.796781384906216 0.22582437677125955 AVSLDSPVSVGS(ph)SPPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AVSLDSPVSVGSSPPVK 17 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 AVSLDSPVSVGS(0.614)S(0.385)PPVK;AVSLDS(0.002)PVS(0.002)VGS(0.976)S(0.02)PPVK 213.0 3.4356000000000004e-22 67779000.0 94994.0 106296.0 100649.0 105220.0 126253.0 99564.0 100809.0 97405.0 95458.0 81274.0 True False 111074.60798297747 116848.36439420882 103048.85387345814 99324.8645278425 101514.63096474379 94342.68856759516 91259.64172604303 94848.22195912842 96853.89266120641 96008.33283536992 1.1569267448216438 1.2170648207648216 1.0733323955344682 1.0345442066800554 1.0573522939807296 0.982651044773052 0.9505387608649585 0.9879165605528137 1.008807150388565 1.0 16.550872006409797 -5.575845759066684 1.027834924604873 0.9879766655440103 1.2088421438472927 0.8423443854275723 0.031406734620326 0.2609251413716406 0.47445272317888154 0.011903283245954507 0.047850771180955654 2.6555485202068845e-06 5.575845759066684 0.2208654783032824 AVSLDSPVSVGS(ph)SPPVK ddPTM_PC-9_Lapatinib_30min_R1 1 AVSLDSPVSVGSSPPVK 17 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 AVSLDS(0.035)PVS(0.361)VGS(0.374)S(0.23)PPVK 89.624 0.0025242 47506000.0 25268.0 27612.0 32950.0 32760.0 26958.0 23649.0 18333.0 18223.0 26455.0 16964.0 True False 24907.673686416318 27548.06611047622 30240.9781906782 35169.27968415634 25372.38344146721 22637.58739851158 19282.193035942073 19069.707106332186 23475.359316499846 19896.20479689086 1.2518806446095987 1.3845889902973405 1.519937018109298 1.7676375993904212 1.2752373480510264 1.1377841970167653 0.9691392520725994 0.9584595303980873 1.179891318778961 1.0 14.280205642334428 -6.673131805277819 2.8554163879520686 1.0327657130037704 1.479554244441725 0.6826808759744414 0.13834393451866914 0.159648314971287 2.6350245330695743 0.05270319807249142 0.051494423551826846 2.122600170223152e-07 6.673131805277819 0.4467885314379545 AVSLDSPVSVGSS(ph)PPVK ddPTM_PC-9_Lapatinib_30min_R1 1 AVSLDSPVSVGSSPPVK 17 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 AVSLDS(0.109)PVS(0.033)VGS(0.358)S(0.5)PPVK 191.89 4.9605e-09 57283000.0 47753.0 46970.0 52134.0 40591.0 46242.0 43218.0 36900.0 39798.0 47077.0 36474.0 True False 47072.03346317233 46861.24385082821 47847.7437630597 43576.19754760656 43522.13647526993 41369.66688607862 38810.50144691336 41647.160369742014 41774.69251721273 42778.482301449985 1.1003670754718855 1.0954396072447814 1.1185002643592592 1.018647581756998 1.0173838372427424 0.9670671950107119 0.9072435336397586 0.9735539488349351 0.9765351707158804 1.0 15.384597678905791 -6.124434474383793 1.4047242945739673 0.9609790621904465 1.1066480396554605 0.8212741721974133 0.027319405939787034 0.16379694518637053 0.6513529209783692 0.010220795643124671 0.016191119003871716 7.508713357698325e-07 6.124434474383793 0.14566897746501406 AVSPPHLDGPPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 6 AVSPPHLDGPPSPR 14 0 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BVD2;H3BT57;H3BUJ5;H3BRN3;P29590-2 P29590;P29590-2 PML Protein PML 1 AVSPPHLDGPPS(1)PR;AVSPPHLDGPPS(1)PR;AVSPPHLDGPPS(1)PR;AVSPPHLDGPPS(1)PR;AVSPPHLDGPPS(1)PR;AVSPPHLDGPPS(1)PR 127.32 1.6522000000000002e-05 115176000.0 116079.1 139477.5 181600.6 217666.2 192887.9 196207.8 165450.9 221133.0 162228.7 182312.0 True False 152989.839204729 184560.87424382893 179192.4573882758 167486.62049926666 166108.74457251187 183938.8952488871 180175.70957913666 186961.97598081967 170803.7778855448 175929.31237145435 0.8696097150752724 1.0490626704329409 1.0185480462171743 0.9520108857450547 0.9441788996582475 1.0455272789364483 1.0241369510881537 1.0627107754850489 0.9708659437314939 1.0 17.4246363511624 -6.767166516947779 24.993044170732603 1.0247856616819757 0.9733251246288076 0.2165543633391107 0.05023205573820193 236.60841221345734 1032545.3280781887 0.017369379881713193 0.01573330602724246 1.7093597876519118e-07 6.767166516947779 -0.05146053705316811 AVSPPHLDGPPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AVSPPHLDGPPSPR 14 0 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BVD2;H3BT57;H3BUJ5;H3BRN3;P29590-2 P29590;P29590-2 PML Protein PML 1 AVSPPHLDGPPS(1)PR;AVSPPHLDGPPS(1)PR;AVSPPHLDGPPS(1)PR 133.52 5.602899999999999e-06 47475300.0 55755.0 66670.0 69556.0 72203.0 78821.0 71131.0 80192.0 61404.0 66400.0 53027.2 True False 65193.22028855407 73288.55699331975 71214.47883259882 68157.6999952843 63376.59087128281 67400.76514103106 72595.63322019727 59792.210062915845 67370.97438354169 62640.61159691577 1.0407500601696549 1.1699846972268109 1.136873938761243 1.0880752639177644 1.011749235130445 1.0759914921448448 1.1589228037449695 0.9545278779790813 1.0755159099828908 1.0 15.934810678122368 -7.454034692419454 0.35476241810745823 0.9970379026564692 1.124850865309502 0.21222053112111028 0.059696241660191926 2.0603107772946014 0.7022439363087393 0.07788493832886735 0.09180063959007428 3.515323582116989e-08 7.454034692419454 0.12781296265303277 AVSPPHLDGPPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 AVSPPHLDGPPSPR 14 0 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BVD2;H3BT57;H3BUJ5;H3BRN3;P29590-2 P29590;P29590-2 PML Protein PML 1 AVSPPHLDGPPS(1)PR;AVSPPHLDGPPS(1)PR 124.45 2.1572e-05 13836200.0 111241.0 101546.0 112754.0 91013.0 102486.0 111433.0 92540.0 94822.0 105342.0 71710.0 True False 109654.68294089926 101310.87647596764 103483.80136302691 97706.39963046779 96457.97497522846 106667.27035301032 97331.26839830258 99227.77628472964 93477.27465956248 84104.97795243109 1.303783504977777 1.2045764584025933 1.230412323769424 1.161719579615484 1.1468759320023139 1.268263460140733 1.1572593057851124 1.1798085999243928 1.1114356954285425 1.0 16.35990357188183 -14.522878745252209 0.10187127666144626 0.3469839026657678 1.3285811167006827 0.7226342386641986 0.04251878924603271 101.28241346934271 0.6964764151747189 13.840961545532048 0.6883318077695769 3.0000000001943065e-15 14.522878745252209 0.981597214034915 AVSPPPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 AVSPPPSPR 9 0 H9KVB4;O15417;O15417-2 H9KVB4 TNRC18 Trinucleotide repeat-containing gene 18 protein 1 AVS(0.047)PPPS(0.953)PR 79.986 0.019347 3277700.0 30133.0 28781.0 33031.0 28551.0 31230.0 29160.0 22327.0 27575.0 27958.0 17841.0 True False 29703.297894284588 28714.35936279937 30315.31868334724 30650.735783343975 29393.112800542374 27912.894775280045 23482.982813149978 28856.23516748671 24809.075629208197 20924.793078361803 1.419526481482896 1.3722649134577445 1.4487750760458473 1.4648047255979657 1.4047026745004043 1.333962762295824 1.122256393418465 1.3790451862258442 1.1856306313902385 1.0 14.352925735835353 -8.377443659705076 0.35780522993617714 0.9728474080707233 1.4563138496614714 0.7400603219164885 0.07564348038977693 0.7733760787978964 0.2933650175599463 0.13666408223673449 0.08451918033272797 4.19330392184867e-09 8.377443659705076 0.48346644159074803 AVSPS(ph)NPK ddPTM_PC-9_AZD4547_30min_R2 1 AVSPSNPK 8 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 AVS(0.336)PS(0.664)NPK 71.61399999999999 0.03493 35096000.0 221950.0 204970.0 326280.0 405430.0 338280.0 334110.0 383530.0 476840.0 351010.0 454230.0 True False 292525.48315320874 271222.54409318743 321953.3140124355 311964.377331059 291315.66113783786 313218.0488828968 417663.42700394103 403155.33469312114 369563.6719988825 438327.5459568513 0.6673673280437749 0.6187668253910887 0.734503950258532 0.7117152006727148 0.6646072413767827 0.7145753256258501 0.9528569008643951 0.9197581544026611 0.8431221706409986 1.0 18.741649819889865 -7.20200765409679 4.97758454162028 0.9224239696605043 0.6823748691320901 0.8669542741730206 0.046815577786785585 0.07552091725247802 3.9226554546265344 0.01862776274845855 0.014101778362708066 6.280472898789726e-08 7.20200765409679 -0.24004910052841422 AVSPS(ph)NPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVSPSNPK 8 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 AVS(0.251)PS(0.749)NPK 68.847 0.042479 25551000.0 143380.0 169380.0 230070.0 218470.0 278590.0 226520.0 218240.0 247090.0 190860.0 185710.0 True False 167651.40211591558 186194.9270065769 235555.74134533413 206229.83418929647 224002.2893750487 214640.8924343301 197566.72727922804 240604.1493134957 193650.96642835424 219377.7529204485 0.7642133255723059 0.8487411532294049 1.0737448907627025 0.9400672194143598 1.0210802435207602 0.9784077445271486 0.9005777689357151 1.0967572878766079 0.8827283708142303 1.0 17.743057704012458 -5.0568057027410065 4.839846124725083 0.985982842297467 0.7801438684738464 0.5671831561863891 0.06480871026799073 0.1207086265304437 5.905898275918731 0.015337717342811147 0.04725903536666846 8.773932667893868e-06 5.0568057027410065 -0.2058389738236206 AVSPT(ph)EPTPR ddPTM_PC-9_AZD4547_30min_R2 2 AVSPTEPTPR 10 0 Q6PJI9-3;Q6PJI9;H3BMH3;Q6PJI9-2 Q6PJI9-3 WDR59 WD repeat-containing protein 59 1 AVS(0.036)PT(0.95)EPT(0.013)PR;AVS(0.025)PT(0.973)EPT(0.002)PR 123.96 0.0010482999999999998 28348000.0 87880.0 86907.0 99449.0 133794.0 125338.0 104370.0 102535.0 120566.0 84554.0 83401.0 True False 115824.01198244626 114997.98819098731 98130.24128117766 102949.8603966941 107936.98219136347 97843.72740087972 111660.4163633848 101935.29503106025 89023.35181958778 80481.15637528867 1.4391444805086004 1.428880912877848 1.219294623745094 1.2791796866912852 1.3411460154479709 1.215734611772081 1.3874106858343993 1.2665734393244747 1.1061390743998052 1.0 16.296363413879135 -14.239248837912628 0.08249515738775656 1.6059040364394009e-09 1.6039034535330827 0.6700314950846734 0.07664589959526194 148.0224389481595 0.9056496294899985 26.876602488380676 2.5821562242611993 5.764360878984242e-15 14.239248837912628 1.6039034519271786 AVSPT(ph)EPTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVSPTEPTPR 10 0 Q6PJI9-3;Q6PJI9;H3BMH3;Q6PJI9-2 Q6PJI9-3 WDR59 WD repeat-containing protein 59 1 AVS(0.038)PT(0.962)EPTPR 127.51 0.00075883 14661000.0 91176.0 90260.0 92821.0 100100.0 112330.0 96357.0 101770.0 102130.0 95321.0 70536.0 True False 106610.2959919145 99220.416292441 95034.20466560296 94491.72152857888 90319.7428676522 91303.86929319605 92129.60884900557 99449.19571567969 96714.88929538516 83323.6184373312 1.2794727112349007 1.190783815600447 1.140543419115667 1.1340328624788105 1.083963281498425 1.0957741755042347 1.1056842054728753 1.1935294887664625 1.160713986132584 1.0 16.346437871211286 -4.70479619007607 1.2180562043354548 1.1163182019312312 1.375818979625063 0.5449029310228608 0.048276541490977355 1.4190224700716072 1.6011108107868448 0.01471951466558722 0.4882713605834169 1.9733485910045364e-05 4.70479619007607 0.25950077769383184 AVSPT(ph)EPTPR ddPTM_PC-9_Lapatinib_30min_R1 1 AVSPTEPTPR 10 0 Q6PJI9-3;Q6PJI9;H3BMH3;Q6PJI9-2 Q6PJI9-3 WDR59 WD repeat-containing protein 59 1 AVS(0.038)PT(0.958)EPT(0.004)PR 115.7 0.0026951 9149600.0 121000.0 103300.0 136170.0 113350.0 110120.0 114170.0 95813.0 111040.0 116260.0 82386.0 True False 119274.51781131777 103060.81519673302 124974.62823140089 121686.13712451559 103642.95810424983 109287.21524326905 100773.72832339047 116199.32377144984 103165.57452792568 96626.31032755529 1.2343896544014452 1.0665916441118914 1.293380941564954 1.2593478599359693 1.0726163273016291 1.1310295805851878 1.042922243245921 1.202564015717289 1.0676758139496667 1.0 16.560128452780965 -6.270040027706741 24.733494815968207 1.0963469857582806 1.2086502070409437 0.4027736687078628 0.07523282132760746 637.1037437103923 1832162.2920669387 0.02303360368351254 0.02656091970839399 5.369823019337318e-07 6.270040027706741 0.11230322128266312 AVSSSPDEETGS(ph)PCR ddPTM_PC-9_Lapatinib_30min_R1 1 AVSSSPDEETGSPCR 15 0 Q0VDD7-2;Q0VDD7;K7EMZ7 Q0VDD7-2 C19orf57 Uncharacterized protein C19orf57 1 AVSSSPDEET(0.001)GS(0.999)PCR 238.83 3.5948999999999997e-32 4220600.0 5304.1 5389.1 8866.7 6387.8 6950.5 6356.0 5129.1 7611.3 8931.8 5286.2 True False 5228.462561347189 5376.62187005532 8137.714152451784 6857.580121076132 6541.685255208767 6084.16869655967 5394.659701120954 7964.948784416736 7925.806627976305 6199.912626581259 0.843312297488014 0.8672092969510256 1.312553037854513 1.1060768972251667 1.0551253943744634 0.9813313611025173 0.8701186655424956 1.2846872632153123 1.2783739232058717 1.0 12.598032168857385 -7.775110408362369 24.999176971398455 1.211147960860499 1.016518326343629 0.22934775675616093 0.15054009716882175 359.9207126862723 658149.8495782408 0.08571209371232535 0.041522995993385416 1.6783772790058524e-08 7.775110408362369 -0.19462963451686988 AVSTPS(ph)NEGAIIFLPPWLFSR ddPTM_PC-9_AZD4547_30min_R2 1 AVSTPSNEGAIIFLPPWLFSR 21 0 O95971-4;O95971-3 O95971-4 1 AVS(0.286)T(0.286)PS(0.427)NEGAIIFLPPWLFSR 47.618 0.034010000000000006 5561700.0 13648.0 9667.7 17060.0 37290.0 26809.0 18031.0 11622.0 23496.0 13658.0 21817.0 True False 17987.780103964797 12792.594962822413 16833.77325319402 28693.36662475689 23087.03310702469 16903.51871960584 12656.335485202728 19865.233084367013 14379.933996640375 21053.193470577982 0.8543967512151006 0.6076320431244873 0.7995828887773896 1.3628985391150334 1.096604804363244 0.802895710013241 0.601159890678346 0.9435733876729365 0.6830286349069302 1.0 14.361751465797163 -6.961010317024554 24.798419136105434 0.7879223602659595 0.9416481062113151 0.09202266382380975 0.21352110953094547 381.1753121536006 242435.85543510053 0.08254641224378396 0.07279898573449309 1.0939303787426532e-07 6.961010317024554 0.1537257459453556 AVSTVFSTSSLMLALS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 AVSTVFSTSSLMLALSR 17 0 F5H8E2;F8W679;M0QYN2;F5GXW4;M0R060;F5H5T6;Q9NX18 F5H8E2 SDHAF2 Succinate dehydrogenase assembly factor 2, mitochondrial 1 AVS(0.001)T(0.002)VFS(0.016)T(0.016)S(0.016)S(0.174)LMLALS(0.775)R 59.88399999999999 0.032905000000000004 15292000.0 14714.0 16435.0 23958.0 38587.0 26066.0 21722.0 16835.0 28125.0 18551.0 22220.0 True False 19392.74592978737 21747.29234605815 23640.301266120903 29691.36331320714 22447.185831911134 20363.71990612155 18333.28238628359 23778.927498204903 19531.56798738289 21442.08456324162 0.9044244682736 1.0142340536861678 1.1025187964535736 1.3847237298983206 1.046875165784607 0.9497080307682061 0.8550139951277181 1.1089839436119637 0.9108987481966213 1.0 14.388157548538219 -6.527935390840012 18.01429989859848 0.9685759267943634 1.110377895429134 0.20153164335996154 0.12816735358657957 7.529669646759972 26812.876345734687 0.04472492431437655 0.04513002255224854 2.965272494633726e-07 6.527935390840012 0.14180196863477046 AVSTVVVTT(ph)APSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVSTVVVTTAPSPK 14 0 Q6P4R8-3;Q6P4R8;Q6P4R8-2 Q6P4R8-3 NFRKB Nuclear factor related to kappa-B-binding protein 1 AVSTVVVT(0.017)T(0.607)APS(0.376)PK 162.88 3.1888e-13 0.0 79369.0 86669.0 64438.0 83277.0 86006.0 69091.0 82161.0 77584.0 71487.0 61324.0 True False 92804.60409079441 95272.92554453346 65974.44630247598 78611.25967767663 69153.74169923685 65467.74633224582 74378.11528587155 75547.50220704313 72532.36213488311 72441.55575948308 1.2810962315458787 1.3151695121078568 0.9107265244484963 1.0851680206686602 0.9546142538522742 0.9037319207998327 1.0267327158574306 1.0428752035347262 1.0012535122202721 1.0 16.144529909581173 -5.253966926993976 24.972250585184643 0.9924438764039607 1.2981329146780025 0.8390709100584958 0.0538615266107498 202.28532157459014 676014.8643568718 0.013883981602355901 0.03521871253226675 5.572281821427738e-06 5.253966926993976 0.3056890382740418 AVSTVVVTTAPS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 AVSTVVVTTAPSPK 14 0 Q6P4R8-3;Q6P4R8;Q6P4R8-2 Q6P4R8-3 NFRKB Nuclear factor related to kappa-B-binding protein 1 AVSTVVVT(0.002)T(0.005)APS(0.993)PK;AVSTVVVT(0.005)T(0.109)APS(0.886)PK 136.83 5.2765e-05 37905000.0 161071.0 136762.0 120986.0 170357.0 149906.0 170936.0 152404.0 135704.0 133963.0 145292.0 True False 212288.22751507317 180967.64197332546 119381.6465891518 131083.82563941288 129094.13946591232 160247.34489792792 165967.6607543308 114734.06496769386 141044.01068911524 140205.37130344313 1.5141233573400183 1.290732589564358 0.851476983223253 0.9349415391205754 0.9207503126718088 1.1429472594962744 1.1837468080672242 0.8183285982630272 1.0059815068272746 1.0 17.09718209485812 -5.040153517511737 3.779000806883188 0.9858395446771469 1.4864849580226234 0.7158550173087436 0.10985238672232893 0.11815536768511446 3.4796479622674235 0.03033123248729735 0.11243905381214216 9.11688512230696e-06 5.040153517511737 0.5006454133454765 AVSTVVVTTAPS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVSTVVVTTAPSPK 14 0 Q6P4R8-3;Q6P4R8;Q6P4R8-2 Q6P4R8-3 NFRKB Nuclear factor related to kappa-B-binding protein 1 AVSTVVVT(0.001)T(0.006)APS(0.993)PK 120.21 9.005200000000001e-05 17176000.0 135170.0 135220.0 111130.0 156520.0 138590.0 124550.0 156820.0 129610.0 115730.0 122120.0 True False 158051.6112708075 148643.7479621528 113779.76066287182 147750.69184468695 111434.28437663929 118018.37874225593 141964.87432152007 126207.87483314631 117422.33231035022 144259.38929861214 1.0956071007873598 1.030392189270018 0.7887165002989962 1.0242015619437286 0.7724577576435876 0.8180984219887539 0.9840945189893845 0.8748676633581209 0.8139666532712814 1.0 17.138305695932942 -5.0852557485600105 5.358481308122315 0.8826216890659114 1.0815722347190133 0.4145881787011544 0.08624449528006752 0.17977288663410312 8.347058806093207 0.021216021351274116 0.06083591521238256 8.21758587917033e-06 5.0852557485600105 0.19895054565310188 AVSTVVVTTAPS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 AVSTVVVTTAPSPK 14 0 Q6P4R8-3;Q6P4R8;Q6P4R8-2 Q6P4R8-3 NFRKB Nuclear factor related to kappa-B-binding protein 1 AVSTVVVT(0.068)T(0.229)APS(0.703)PK;AVSTVVVT(0.005)T(0.013)APS(0.982)PK;AVSTVVVT(0.013)T(0.055)APS(0.932)PK 143.05 3.1213e-05 25643000.0 255567.0 213749.0 200474.0 209673.0 232993.0 215053.0 220947.0 208178.0 179260.0 196285.0 True False 251922.5677147517 213254.07732319908 183991.80157201854 225093.05186862356 219288.80982186264 205855.68450302802 232386.55455802637 217850.70987115346 159069.85110851482 230212.60071667744 1.0943039908783825 0.9263353815530314 0.7992255897341483 0.9777616480065985 0.9525491182463175 0.8941981623168166 1.0094432443514438 0.9463022840320642 0.6909693501281541 1.0 17.812607276169068 AVT(ph)PLRPGELLFR ddPTM_PC-9_AZD4547_30min_R2 1 AVTPLRPGELLFR 13 1 B0QZ88;Q9H7B4 B0QZ88 SMYD3 Histone-lysine N-methyltransferase SMYD3 1 AVT(1)PLRPGELLFR 61.419 0.03857 5200400.0 9982.5 10566.0 13659.0 21223.0 14759.0 13430.0 14896.0 15222.0 13699.0 11414.0 True False 13156.727351101154 13981.252870608481 13477.87273536794 16330.36524208139 12709.967608884232 12590.219976945613 16221.715142624316 12869.78966676177 14423.101172937206 11014.399334151216 1.1945024827915438 1.2693613556626957 1.2236593504993492 1.4826378403992948 1.1539410569104518 1.1430691402216018 1.472773471389158 1.1684513404973194 1.3094768707193118 1.0 13.427103199938216 -10.669959855445853 3.9992945855687334 0.9998960246352563 1.2696327142390305 0.3238148744553583 0.11645756805326707 12534329.518042842 6688226.883685685 10703.625300105201 0.02727173356491937 2.1381597238387303e-11 10.669959855445853 0.26973668960377417 AVT(ph)PLRPGELLFR ddPTM_PC-9_Lapatinib_30min_R1 1 AVTPLRPGELLFR 13 1 B0QZ88;Q9H7B4 B0QZ88 SMYD3 Histone-lysine N-methyltransferase SMYD3 1 AVT(1)PLRPGELLFR 80.737 0.008952799999999999 3821700.0 15490.0 12299.0 14373.0 12302.0 14945.0 14781.0 10891.0 10392.0 16591.0 9569.7 True False 15269.109759481897 12270.522421148302 13191.307421384452 13206.73011826897 14065.964483000507 14148.851086193894 11454.88268992773 10874.850257861168 14722.346869024723 11223.809894176287 1.3604212743664341 1.0932582195209064 1.1752967615951018 1.1766708669149468 1.253225474738211 1.2606103648935933 1.0205877325017185 0.9689089854866318 1.3117067206086346 1.0 13.454274857852631 -7.260641891379609 24.99932367605534 1.072709940093472 1.2116772832320628 0.29534299804767683 0.10895646247344547 98.13516707531926 3076382.557716796 0.04236680954226669 0.030882656810640532 5.487292471570765e-08 7.260641891379609 0.13896734313859072 AVT(ph)PSSEAK ddPTM_PC-9_AZD4547_30min_R2 2 AVTPSSEAK 9 0 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5 Q99700 ATXN2 Ataxin-2 1 AVT(0.737)PS(0.086)S(0.177)EAK;AVT(0.857)PS(0.071)S(0.071)EAK 100.88 0.0089935 226520000.0 176209.0 179889.0 242870.0 266550.0 254000.0 241920.0 228350.0 264770.0 226590.0 231350.0 True False 232239.79662511265 238034.6013288744 239649.38511156128 205101.01565644782 218736.48435914342 226792.7041565656 248672.70762743402 223855.88030932302 238567.08480734672 223250.50691745942 1.040265483970331 1.066221997054103 1.073455054685116 0.9187034712188946 0.9797804599835245 1.0158664689635657 1.1138729808993166 1.0027116327762131 1.0686071359988005 1.0 17.768303925601785 -7.054991178176223 24.998330618640257 1.0491447398740867 1.0144650821784138 0.07724889467717966 0.05131991224273749 839.0428883531125 381415.9013009175 0.02078487627979569 0.01610000133491936 8.810667699354716e-08 7.054991178176223 -0.03467965769567294 AVT(ph)PSSEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AVTPSSEAK 9 0 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5 Q99700 ATXN2 Ataxin-2 1 AVT(0.872)PS(0.099)S(0.029)EAK;AVT(0.827)PS(0.153)S(0.019)EAK;AVT(0.961)PS(0.03)S(0.009)EAK;AVT(0.93)PS(0.066)S(0.004)EAK 105.17 0.006490300000000001 229507000.0 844760.0 874440.0 954500.0 1026390.0 1156620.0 962630.0 1079070.0 1017260.0 881740.0 796380.0 True False 987761.1832294655 961248.624227365 977258.8999614092 968884.6959012763 929988.6138661429 912147.9881867359 976852.677809732 990558.0028760611 894633.7794118075 940757.3898593909 1.0499637779907314 1.0217816352960425 1.0388001311448363 1.0298985757062078 0.9885530784989555 0.9695889695036771 1.0383683278382072 1.052936722638037 0.9509718329669702 1.0 19.843463191466213 -6.132084083449003 5.87136370060069 1.003199208759794 1.0351389087306966 0.26172379666313794 0.028652458077784528 0.3877385651691152 16.8996489437826 0.008774249296358264 0.011425975048363683 7.377613788395266e-07 6.132084083449003 0.03193969997090251 AVT(ph)PSSEAK ddPTM_PC-9_Lapatinib_30min_R1 1 AVTPSSEAK 9 0 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5 Q99700 ATXN2 Ataxin-2 1 AVT(0.908)PS(0.034)S(0.059)EAK 88.134 0.025314 101320000.0 120980.0 133660.0 155010.0 142890.0 143070.0 132640.0 127820.0 114930.0 129030.0 112800.0 True False 119254.80301498488 133350.51848204568 142265.67615590355 153398.6072670666 134654.9038864423 126967.29639894194 134437.89417193658 120270.06737259285 114497.28265386404 132297.32970344787 0.9014150420292036 1.007960771248812 1.0753480548307386 1.1594988924638046 1.0178202703582837 0.9597117090990913 1.0161799521826096 0.9090891527605672 0.8654542227761991 1.0 17.013424416911512 -7.371273826545776 1.41401172254154 0.919777344776135 1.0360213086522927 0.24851893932672142 0.0718535513256214 0.5827275298330331 2.2487523404142875 0.04952664603622061 0.02647772812647231 4.2533015411565477e-08 7.371273826545776 0.11624396387615765 AVT(ph)PVPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVTPVPTK 8 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YBW1 Q6PKG0 LARP1 La-related protein 1 1 AVT(0.906)PVPT(0.094)K 83.99799999999999 0.034979 15803000.0 74464.0 112160.0 110090.0 105750.0 111590.0 80876.0 102510.0 76402.0 84031.0 64858.0 True False 87069.28446896038 123294.50356038348 112714.96311864976 99825.17034612568 89724.74055551742 76634.72018593898 92799.51069186983 74396.52845461029 85259.79440396678 76616.24198435454 1.1364337667036764 1.609247600339898 1.4711627743588205 1.3029243899291032 1.1710929462429092 1.0002411786470577 1.2112250390827053 0.9710281596662295 1.1128161887838 1.0 16.225362643062493 -6.238894568907719 2.159001365373146 1.067548627563259 1.4226825524517532 0.5839968499663841 0.12843459946169872 0.2126667836734244 1.9463897813963646 0.041739590501465904 0.054661380917046004 5.769064985584618e-07 6.238894568907719 0.35513392488849416 AVT(ph)PVPTKTEEVSNLK ddPTM_PC-9_AZD4547_30min_R2 2 AVTPVPTKTEEVSNLK 16 1 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YBW1 Q6PKG0 LARP1 La-related protein 1 1 AVT(0.572)PVPT(0.023)KT(0.399)EEVS(0.007)NLK;AVT(0.939)PVPT(0.048)KT(0.011)EEVS(0.002)NLK 90.49799999999999 0.02005 531543000.0 160142.0 134046.0 237328.0 366735.0 307832.0 242006.0 208460.0 219930.0 179177.0 240001.0 True False 211063.8248394734 177373.74808760037 234180.87565263978 282189.9117492682 265094.84036710113 226873.32656297064 227012.5361594698 185944.87198862908 188647.93042290484 231598.6380406188 0.9113344820380856 0.765866973952117 1.0111496234773543 1.2184437444739051 1.1446303942452702 0.9795969807179116 0.9801980619577536 0.8028754985856922 0.8145468039834454 1.0 17.821267243749183 -7.643172056049263 5.53427941488559 0.8575381571820111 1.0081261252738896 0.1807660745341626 0.12532123162377495 0.36322322387953687 16.072041101339945 0.06862663629818352 0.038698968650006035 2.2741962755370606e-08 7.643172056049263 0.15058796809187847 AVT(ph)PVPTKTEEVSNLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVTPVPTKTEEVSNLK 16 1 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YBW1 Q6PKG0 LARP1 La-related protein 1 1 AVT(0.659)PVPT(0.134)KT(0.202)EEVS(0.005)NLK 63.443000000000005 0.024077 429550000.0 196390.0 119080.0 177300.0 287100.0 277500.0 309950.0 269950.0 300540.0 284520.0 200990.0 True False 229634.94812069155 130901.47542769625 181527.50441399412 271014.71779075795 223125.86705041744 293695.6763642094 244378.3817312485 292651.1434484512 288680.56674104213 237427.8959640353 0.9671776232876856 0.5513314890661573 0.7645584512170854 1.141461144194321 0.9397626430729762 1.2369889189798378 1.0292740907254891 1.2325895500197706 1.2158662551799322 1.0 17.857129925021603 -5.743479646819381 7.22478409074564 1.1180634793617386 0.7378669867847358 0.5919784736466785 0.1337670175492065 0.0991189571272227 22.818098713030324 0.03545956943733549 0.059351381575182646 1.805179334752904e-06 5.743479646819381 -0.3801964925770027 AVT(ph)PVPTKTEEVSNLK ddPTM_PC-9_Lapatinib_30min_R1 2 AVTPVPTKTEEVSNLK 16 1 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YBW1 Q6PKG0 LARP1 La-related protein 1 1 AVT(0.988)PVPT(0.008)KT(0.003)EEVS(0.002)NLK;AVT(0.973)PVPT(0.022)KT(0.005)EEVSNLK 106.3 0.010661 108895000.0 348230.0 203283.0 280750.0 244210.0 195588.0 192541.0 158993.0 170920.0 251820.0 144909.0 True False 343264.1763424383 202812.31070317022 257667.81872633976 262170.0180606785 184083.89838080303 184306.470264993 167224.87958127636 178861.567174137 223457.37981784152 169956.32757089502 2.019719896567253 1.1933201523113035 1.5160825278414953 1.5425728586146212 1.0831247121647465 1.0844342949697592 0.9839285301779701 1.0523972230426506 1.3147929412903396 1.0 17.37480454967453 -1.5228787452807857 0.40024738365438356 1.063942170768121 13.929970577301686 0.628792468963557 0.19028746937769098 51.02315635929324 0.6765411507726601 0.1403633190717883 517.7529697182151 0.029999999999969044 1.5228787452807857 12.866028406533566 AVT(ph)PVSQGSNSSSADPK ddPTM_PC-9_AZD4547_30min_R2 2 AVTPVSQGSNSSSADPK 17 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 AVT(0.999)PVS(0.001)QGSNSSSADPK;AVT(0.998)PVS(0.002)QGSNSSSADPK 226.08 1.3022e-28 27676000.0 140021.0 148197.0 177751.0 244800.0 210312.0 199779.0 171965.0 219095.0 180956.0 186739.0 True False 184544.76538227237 196098.78209971281 175393.9055995598 188365.14212229758 181113.80904937087 187286.7875483411 187269.5518596528 185238.90205223797 190520.96473100415 180201.32444892777 1.0241032686448184 1.0882205372208054 0.9733219560729118 1.0453038716465348 1.0050636953043135 1.0393197060070525 1.0392240591590562 1.027955275127503 1.057267283210236 1.0 17.45925008918914 AVT(ph)PVSQGSNSSSADPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AVTPVSQGSNSSSADPK 17 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 AVT(0.999)PVS(0.001)QGSNSSSADPK;AVT(0.995)PVS(0.005)QGSNSSSADPK;AVT(0.481)PVS(0.026)QGS(0.007)NS(0.301)S(0.092)S(0.092)ADPK;AVT(0.978)PVS(0.02)QGS(0.001)NS(0.001)SSADPK 161.95 7.4964e-05 37736200.0 231980.0 212507.0 214170.0 260306.0 301763.0 237817.0 255720.0 236922.0 222145.0 208178.0 True False 271249.6321861498 233603.29055016363 219276.62504424786 245721.89874343807 242634.70637382107 225345.45786709865 231496.35034752585 230703.04853960962 225393.45036794984 245919.02346385852 1.1030038602361887 0.9499195599420357 0.8916619054339805 0.9991984161385976 0.9866447213242121 0.9163400809462654 0.9413519421426447 0.9381260761777337 0.9165352366531123 1.0 17.907823815696197 -4.76203250517128 7.368843635514051 0.9464697456143153 1.105703269941939 0.6369717414094203 0.03487682364513957 0.06421660348433068 23.66612818725516 0.00866998748652929 0.051300932749683274 1.729686894358379e-05 4.76203250517128 0.1592335243276236 AVT(ph)PVSQGSNSSSADPK ddPTM_PC-9_Lapatinib_30min_R1 2 AVTPVSQGSNSSSADPK 17 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 AVT(1)PVSQGSNSSSADPK;AVT(0.996)PVS(0.003)QGSNSSSADPK 203.17 9.444e-17 35259000.0 197134.0 168613.0 185640.0 163059.0 162794.0 178346.0 156412.0 158243.0 170348.0 142522.0 True False 194322.8330100515 168222.58695805172 170377.39579112324 175050.90280887805 153218.7769853184 170718.5573248318 164510.24803020633 165595.5474744729 151161.61439603544 167156.73780137222 1.1625186969188164 1.0063763457620596 1.0192672938710854 1.0472261250807984 0.9166174154905086 1.0213082617566513 0.9841676153412934 0.9906603206820509 0.904310627165126 1.0 17.35084198312658 -1.5228787460920603 0.8360626734009488 0.9785130773122569 56.613283489070575 0.613434153932964 0.042022015072615805 411.29036710165855 1.2168401049389206 0.014189499499402788 43476.17369984681 0.029999999943928178 1.5228787460920603 55.63477041175832 AVTDFVIPECQKKS(ph)PISK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVTDFVIPECQKKSPISK 18 2 Q6P0N0 Q6P0N0 MIS18BP1 Mis18-binding protein 1 1 AVTDFVIPECQKKS(0.909)PIS(0.091)K 55.097 0.012988999999999999 4677400.0 22829.0 7701.0 14280.0 33148.0 31007.0 32663.0 29234.0 57467.0 39355.0 28366.0 True False 26693.49880669719 8465.50438586404 14620.489357201583 31290.825027265975 24931.40093561192 30950.09478007473 26464.74388416854 55958.55214131954 39930.49242265479 33508.53125486755 0.7966179897192484 0.2526372857549319 0.43632140263019636 0.9338166686348145 0.7440314451857781 0.9236482060245128 0.7897912231030476 1.6699792573925731 1.1916515265602508 1.0 15.032240831303497 -6.837457297100375 0.7981172492084796 1.2784543915657545 0.5062110760777526 0.5117117284470853 0.2580774143838457 0.48938973821259024 0.6736364080568237 0.18189149178094968 0.16150107048295972 1.453927338980301e-07 6.837457297100375 -0.7722433154880018 AVTELNEPLSNEDR ddPTM_PC-9_AZD4547_30min_R2 2 AVTELNEPLSNEDR 14 0 Q04917 Q04917 YWHAH 14-3-3 protein eta 0 ; 204.85 4.7842e-10 7358400.0 17507.1 19552.4 21967.0 23165.0 23747.0 22455.0 20746.4 26664.0 21678.0 24067.0 False True 23073.99362969827 25872.33093197856 21675.70322701718 17824.667145682302 20450.13895305738 21050.885300246748 22592.78940889776 22543.691477764813 22823.854823485854 23224.421655424674 0.9935228515931088 1.114014002838921 0.9333150917002168 0.7674967071362521 0.8805445946715625 0.9064116046708858 0.972803101153678 0.9706890364048804 0.9827523441538422 1.0 14.503355049989901 -10.388342358513682 15.13916475278193 1.0000002389159022 0.9444095037105126 0.03384644467903741 0.08431404461897953 0.0 0.0 0.09144390939529178 0.022178405720952896 4.089381627493596e-11 10.388342358513682 -0.055590735205389596 AVTELNEPLSNEDR ddPTM_PC-9_Lapatinib_30min_R1 2 AVTELNEPLSNEDR 14 0 Q04917 Q04917 YWHAH 14-3-3 protein eta 0 ; 223.36 1.2031e-19 11926400.0 28444.0 32842.6 35106.0 29620.7 36679.0 35341.0 34914.0 30370.5 31149.0 30309.0 False True 28038.38334400923 32766.55497754332 32219.72019307889 31799.105089758552 34521.61333368856 33829.547813894766 36721.67608448596 31781.62430296121 27640.671606488508 35547.8702657961 0.7887500189002198 0.9217585957342447 0.9063755423930551 0.8945431850626343 0.9711302836306626 0.9516617327830554 1.03302042597526 0.8940514316420598 0.7775619579967963 1.0 15.11747550763567 -4.757292528460388 4.913221389445745 0.9287441286342711 0.7788059856490148 0.2837847190823647 0.06633665343043352 0.2585952356431645 15.80814125858718 0.01704329452697239 0.13532940941059188 1.7486684383271254e-05 4.757292528460388 -0.14993814298525632 AVTEQGAELSNEER ddPTM_PC-9_Lapatinib_30min_R1 2 AVTEQGAELSNEER 14 0 P27348;E9PG15 P27348 YWHAQ 14-3-3 protein theta 0 ; 310.34 2.8769999999999993e-115 59826000.0 75598.0 58821.0 76757.0 77343.0 71228.0 78419.0 72851.0 65464.0 84262.0 64275.0 False True 74519.95865702472 58684.80358845149 70446.33575058832 83031.06222868452 67038.50907963591 75065.20217361748 76622.86831731937 68505.69642808169 74771.52624180351 75384.84810894603 0.9885270120771302 0.7784694810771567 0.9344893240187925 1.1014290578484445 0.8892835995736438 0.9957598119072072 1.0164226663504603 0.9087462288055207 0.9918641227975131 1.0 16.201986959346375 -5.519832660750052 24.99954816423338 0.9829479674777274 0.8767435246431197 0.2459092874174954 0.07219763484711067 143.12795383630467 1174665.3497724158 0.018431179755567267 0.032719500645436744 3.0211155708525976e-06 5.519832660750052 -0.10620444283460773 AVTEQGHELSNEER ddPTM_PC-9_AZD4547_30min_R2 2 AVTEQGHELSNEER 14 0 P31946-2;P31946;Q4VY20;Q4VY19;A0A0J9YWE8;A0A0J9YWZ2 P31946-2 YWHAB 14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed 0 ; 223.03 2.2685000000000003e-20 95516000.0 106844.0 74069.0 170691.0 231380.0 210677.0 168517.0 130452.0 208024.0 131724.0 164078.0 False True 140818.16950674207 98010.35575176043 168427.5258124818 178038.91578536486 181428.13509972935 157979.6053503312 142061.97528098975 175878.670715967 138686.6617201242 158333.6791614565 0.8893759701190707 0.6190114211381207 1.0637504711851757 1.124453854216414 1.1458594031325635 0.9977637492351564 0.89723156837735 1.1108102309466292 0.8759138450809458 1.0 17.27260863825802 -5.275146189007842 24.946503368717405 1.0329810161721684 0.7541936947760832 0.5189582901045088 0.1049225832808654 497.98481535715365 906336.4858292495 0.02725513461524039 0.05721982333403536 5.307057718952446e-06 5.275146189007842 -0.2787873213960852 AVTEQGHELSNEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AVTEQGHELSNEER 14 0 P31946-2;P31946;Q4VY20;Q4VY19;A0A0J9YWE8;A0A0J9YWZ2 P31946-2 YWHAB 14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed 0 ; 203.74 9.9111e-11 67441000.0 126014.0 143752.0 169806.0 170750.0 207517.0 176875.0 186867.0 141088.0 179603.0 130133.0 False True 147345.6813100501 158022.7485361289 173854.81903284142 161183.4310789694 166855.5335232493 167599.36362935792 169165.60496007837 137384.5894950928 182229.35409950654 153725.08276773896 0.958501232571607 1.0279568284564415 1.1309463355145248 1.0485174454093427 1.0854151483876509 1.0902538519532392 1.100442438633572 0.8937031421389132 1.1854236850523234 1.0 17.22999305802265 -4.876222897741537 3.8290532053593958 1.0658405226734393 0.9572883211594326 0.16505066572863336 0.07426477356751542 0.4071482071772624 10.028582119215923 0.01770723207805525 0.10215884057314263 1.329771749401377e-05 4.876222897741537 -0.10855220151400669 AVTEQGHELSNEER ddPTM_PC-9_Lapatinib_30min_R1 2 AVTEQGHELSNEER 14 0 P31946-2;P31946;Q4VY20;Q4VY19;A0A0J9YWE8;A0A0J9YWZ2 P31946-2 YWHAB 14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed 0 ; 218.45 1.1681e-15 83101000.0 135206.0 120524.0 157236.0 124247.0 130009.0 146521.0 122661.0 120122.0 144860.0 95497.0 False True 133277.93764625644 120244.93408297269 144308.66302851215 133384.53885584162 122362.1262275283 140254.6383871333 129011.78639511752 125703.30664692048 128544.341356574 112003.52920824612 1.189944090051441 1.0735816534798959 1.288429606179656 1.1908958565746814 1.0924845591251202 1.2522340981448934 1.1518546541086956 1.12231558715621 1.1476811692029263 1.0 16.773184666460914 -9.16511128909239 0.6448728617163584 0.9952004967453845 1.1784917002005701 0.4146245091522299 0.06182483520187664 2.2540858648543685 1.4229917857869885 0.08686557373505589 0.024227852601381748 6.837364155928674e-10 9.16511128909239 0.18329120345518568 AVTETS(ph)FNSVNVNGQR ddPTM_PC-9_AZD4547_30min_R2 1 AVTETSFNSVNVNGQR 16 0 Q8IZT6-2;Q8IZT6 Q8IZT6-2 ASPM Abnormal spindle-like microcephaly-associated protein 1 AVTET(0.042)S(0.958)FNSVNVNGQR 162.88 6.392399999999999e-05 5380600.0 13566.0 14125.0 10972.0 14990.0 15835.0 12774.0 13167.0 19291.0 12439.0 16528.0 True False 17879.705809670755 18690.63002057021 10826.504111022548 11534.287093191351 13636.583581996187 11975.239760648052 14338.83749214113 16310.019213079846 13096.500145278189 15949.359750731672 1.1210296895366305 1.1718733737705542 0.6788049351338937 0.7231818250674432 0.854992538579526 0.7508288701117731 0.8990227643139933 1.0226127862174297 0.8211301487934267 1.0 13.961210891126825 -5.24501668693129 24.98190512676152 0.8393700139272856 1.1464515959364892 0.5666828659465518 0.10579605367268709 599.0160270195305 911208.9565239924 0.028308250728766426 0.07442781594476706 5.688310741825085e-06 5.24501668693129 0.30708158200920355 AVTFS(ph)PDLGPVPHEGLGEYNR ddPTM_PC-9_AZD4547_30min_R2 2 AVTFSPDLGPVPHEGLGEYNR 21 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 AVT(0.039)FS(0.961)PDLGPVPHEGLGEYNR;AVT(0.066)FS(0.934)PDLGPVPHEGLGEYNR 108.77 2.9256e-05 10135200.0 24673.6 25426.0 38231.0 47585.0 44605.0 41670.0 29949.0 48744.0 31894.0 34761.0 True False 32519.291557238103 33644.45726747032 37724.03196030837 36615.01343092133 38412.36568834483 39064.36831268234 32614.402981099316 41211.73482568886 33579.851727108515 33544.02797042495 0.9694510029001188 1.002993954605986 1.1246124643578537 1.0915508853976632 1.145132770644366 1.1645699898391617 0.9722864233792894 1.2285863481280292 1.0010679622827394 1.0 15.03376831782685 -5.145075028937575 4.350143315153893 1.0993458490316617 0.9770448264076312 0.22531735553319776 0.07722599408507573 0.2819846787530936 8.589555830393891 0.01843416987969713 0.05477299773112341 7.160196995962884e-06 5.145075028937575 -0.12230102262403042 AVTFS(ph)PDLGPVPHEGLGEYNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AVTFSPDLGPVPHEGLGEYNR 21 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 AVT(0.019)FS(0.981)PDLGPVPHEGLGEYNR;AVT(0.051)FS(0.949)PDLGPVPHEGLGEYNR 131.97 1.7223e-05 8186100.0 20089.3 19154.9 20369.4 20582.0 28470.0 21912.4 24024.0 14501.900000000001 20724.0 15839.0 True False 23490.02170823872 21056.471881676032 20855.08374737967 19428.857267744315 22891.50787360504 20763.275169424425 21748.272801302082 14121.24049103315 21027.049294043904 18710.485318544994 1.255446949040732 1.1253835228317568 1.1146201390462622 1.0383940842243842 1.2234587977745293 1.1097133407247752 1.1623574926592721 0.7547233677063849 1.123811004154063 1.0 14.191559359698294 -7.69557604026341 24.999984994346867 0.9544397322532054 1.1422964246919558 0.4160164843048426 0.10166196534283115 49.25984212697973 18697.24603105509 0.04461763333166541 0.025759987019296642 2.015691014085091e-08 7.69557604026341 0.18785669243875036 AVTFS(ph)PDLGPVPHEGLGEYNR ddPTM_PC-9_Lapatinib_30min_R1 2 AVTFSPDLGPVPHEGLGEYNR 21 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 AVT(0.239)FS(0.761)PDLGPVPHEGLGEYNR;AVT(0.219)FS(0.781)PDLGPVPHEGLGEYNR 94.955 0.0002056 8017900.0 24630.0 23540.0 31299.0 25950.0 23080.0 27049.0 21182.0 23141.0 32597.0 22268.0 True False 24278.771683411174 23485.494576293288 28725.717037633905 27858.449566662308 21722.479777025874 25892.177324298693 22278.70031567801 24216.215340373892 28925.582598372537 26116.99412975511 0.9296158494652473 0.8992418675599521 1.099886031865615 1.0666790147539666 0.8317373610877156 0.991391934142977 0.8530346258452411 0.9272206142890058 1.1075387333880664 1.0 14.672701242603827 -8.251000265963379 24.830424214307776 1.053769369729896 0.9512797560957512 0.19671314134225026 0.08395873639966443 987.3047136504582 2348413.833598608 0.06047796780677705 0.022299145616644745 5.610476324449374e-09 8.251000265963379 -0.10248961363414477 AVTHTSPEDVSFAES(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 AVTHTSPEDVSFAESR 16 0 A0A0J9YVU1;I3L439;A0A0J9YWI5;A0A0J9YVR1;J3KR97;Q9BTW9;Q9BTW9-4 A0A0J9YVU1 TBCD Tubulin-specific chaperone D 1 AVTHT(0.011)S(0.011)PEDVS(0.007)FAES(0.97)R 73.833 0.013841999999999998 124690000.0 5118.4 5066.0 22668.0 26499.0 18276.0 17933.0 9849.3 34670.0 13824.0 15194.0 True False 6745.944730666283 6703.485428970527 22367.407508991902 20390.064955468835 15738.692866723233 16811.646675097967 10725.868619377656 29312.5481373427 14554.70841774465 14662.062684693674 0.4600952045927788 0.4571993431707647 1.5255293876449016 1.390668243203929 1.073429653465709 1.1466085663818866 0.7315388598477913 1.9992103954065934 0.9926780924855072 1.0 13.839800458167595 -5.2483896636996095 24.414779472540676 1.247158756026759 0.45864703968592346 0.46604495639228316 0.33100982007264346 475.6228305200003 889839.513218367 0.08259516803504852 0.21540424615424425 5.644303215761419e-06 5.2483896636996095 -0.7885117163408355 AVTHTSPEDVSFAES(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 AVTHTSPEDVSFAESR 16 0 A0A0J9YVU1;I3L439;A0A0J9YWI5;A0A0J9YVR1;J3KR97;Q9BTW9;Q9BTW9-4 A0A0J9YVU1 TBCD Tubulin-specific chaperone D 1 AVTHT(0.001)S(0.001)PEDVS(0.012)FAES(0.986)R 72.615 0.015962999999999998 57209000.0 99457.0 98294.0 268860.0 107730.0 175780.0 197820.0 127310.0 154020.0 238230.0 119070.0 True False 98038.72494181995 98066.4062821655 246755.36862961279 115652.8235767451 165440.96599677674 189359.69974094315 133901.48886738587 161176.3314776538 211398.02872688556 139651.0908491978 0.7020262021990723 0.7022244200588629 1.766941934567998 0.8281555330035537 1.1846736390725952 1.3559485900860109 0.9588288072305813 1.154135857425561 1.5137585209066766 1.0 17.091467317346343 -5.101358775277848 24.99492841785232 1.2079442613634062 0.701634937478952 0.3861919887990918 0.26093728244222214 32.57530904993887 8023.045934784351 0.062901823927027 0.16642277887225698 7.918469070759656e-06 5.101358775277848 -0.5063093238844542 AVTIANS(ph)PSKPSEK ddPTM_PC-9_AZD4547_30min_R2 2 AVTIANSPSKPSEK 14 1 Q8NEF9 Q8NEF9 SRFBP1 Serum response factor-binding protein 1 1 AVT(0.002)IANS(0.829)PS(0.168)KPS(0.002)EK;AVT(0.056)IANS(0.943)PS(0.001)KPSEK 83.964 0.0035258000000000004 130213000.0 231710.0 239830.0 238300.0 190127.0 199590.0 245470.0 268330.0 241180.0 237890.0 212660.0 True False 305388.96013259754 317350.35736873315 235139.98629754575 146296.15758286807 171880.37367417876 230120.7220953712 292210.8501759121 203911.1727650509 250464.37973793977 205214.83812866674 1.4881426846002386 1.5464298793528715 1.145823510822918 0.7128926880576856 0.8375630887197945 1.1213649275745297 1.4239265193518809 0.9936473143194525 1.220498390963826 1.0 17.64677552370882 -5.33015284919349 4.575511029271724 1.0471233189544666 1.5189613289394552 0.501226118144372 0.18523898364638594 0.17918124131931665 7.265167626293752 0.05406440276349857 0.12129025902882361 4.67570551676557e-06 5.33015284919349 0.4718380099849886 AVTIANS(ph)PSKPSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AVTIANSPSKPSEK 14 1 Q8NEF9 Q8NEF9 SRFBP1 Serum response factor-binding protein 1 1 AVT(0.018)IANS(0.905)PS(0.072)KPS(0.005)EK;AVT(0.006)IANS(0.982)PS(0.009)KPS(0.003)EK;AVT(0.002)IANS(0.866)PS(0.102)KPS(0.03)EK 72.819 0.010337 217693000.0 223114.0 284578.0 229527.0 224644.0 232100.0 153051.0 233898.0 178765.0 148122.0 164128.0 True False 260882.7934976323 312829.0231295173 234999.79416599468 212057.92498567494 186621.67114379053 145024.7361291132 211741.48816512438 174072.6081671737 150288.0040307072 193883.10716346678 1.345567426241404 1.61349293244906 1.212069465999746 1.093741110755382 0.9625473506902591 0.7480008869820717 1.0921090097168746 0.8978224596968603 0.7751474908228922 1.0 17.564827582816115 -5.712476659998745 1.6216747174187816 0.9089074902012994 1.4851695633596707 0.7753736648532207 0.1188755418590228 0.16732157868355882 0.8864925177089821 0.0368096148584884 0.08545365264357742 1.9387568264789906e-06 5.712476659998745 0.5762620731583713 AVTIANS(ph)PSKPSEK ddPTM_PC-9_Lapatinib_30min_R1 3 AVTIANSPSKPSEK 14 1 Q8NEF9 Q8NEF9 SRFBP1 Serum response factor-binding protein 1 1 AVT(0.001)IANS(0.655)PS(0.235)KPS(0.109)EK;AVTIANS(0.796)PS(0.192)KPS(0.012)EK;AVTIANS(0.993)PS(0.007)KPSEK 95.662 0.0014826 154427000.0 293248.0 467353.0 397191.0 391537.0 461230.0 435278.0 458162.0 462348.0 356329.0 406289.0 True False 289066.22974490374 466270.8728425817 364535.4891815979 420331.9371091429 434101.35821306927 416662.17462257703 481883.38655611733 483830.37596435717 316195.47570928244 476515.5123039364 0.6066250148862484 0.978500931875602 0.7650023551575081 0.8820949712147925 0.9109910317802749 0.8743937266764507 1.0112648468173207 1.0153507356456322 0.6635575706244861 1.0 18.86216365427967 -4.7517197177766475 24.997950704790398 0.8988301927362596 0.6066244304354206 0.39831947554143554 0.10820793188204451 404.7842699665774 1040990.4658621354 0.02601277896455395 0.3335270429335368 1.7712517087418052e-05 4.7517197177766475 -0.29220576230083906 AVTIANS(ph)PSKPSEKDSVVSLESQK ddPTM_PC-9_AZD4547_30min_R2 2 AVTIANSPSKPSEKDSVVSLESQK 24 2 Q8NEF9 Q8NEF9 SRFBP1 Serum response factor-binding protein 1 1 AVT(0.032)IANS(0.591)PS(0.292)KPS(0.064)EKDS(0.014)VVS(0.004)LES(0.001)QK;AVT(0.004)IANS(0.497)PS(0.497)KPS(0.001)EKDSVVSLESQK 60.761 0.010962000000000001 147236000.0 75628.0 43075.0 75606.0 93578.0 100044.0 85602.0 63082.0 81790.0 67060.0 85339.0 True False 99676.13083987741 56998.15137246457 74603.41503991719 72005.03786568779 86154.61748514237 80249.2934077809 68696.17579397344 69151.23484722423 70604.65469429664 82351.30758516995 1.2103770269438607 0.6921341390179572 0.9059165813822727 0.8743642326652582 1.0461839649120195 0.9744750358066253 0.8341843961970609 0.8397102228851212 0.8573592425508896 1.0 16.329503936989404 -7.26223146843391 24.47984787282708 0.8694559870406956 0.9376796284936713 0.05130716958749959 0.1311938459389648 178.89074480606752 5528503.952763847 0.05139876592148122 0.03699385471300218 5.467244943221932e-08 7.26223146843391 0.06822364145297566 AVTIANS(ph)PSKPSEKDSVVSLESQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVTIANSPSKPSEKDSVVSLESQK 24 2 Q8NEF9 Q8NEF9 SRFBP1 Serum response factor-binding protein 1 1 AVT(0.009)IANS(0.491)PS(0.491)KPS(0.009)EKDSVVSLESQK 74.444 9.7275e-05 83865000.0 125400.0 62792.0 88670.0 147740.0 120060.0 146310.0 139260.0 173340.0 125490.0 98941.0 True False 146627.7432371028 69025.57478212903 90784.22908284765 139462.6067795428 96535.10485792141 138637.24603596528 126068.2846449104 168790.00866891147 127325.05384624444 116878.22008347501 1.2545343617688611 0.5905768819274507 0.7767420569718558 1.1932300704095076 0.8259460555523138 1.1861683548650028 1.0786294020808307 1.4441527989420166 1.0893822112905915 1.0 16.834646587325558 -6.773283509337167 24.532105660138978 1.1823613732405596 0.9157576350906612 0.2264388069520764 0.21121197798878233 241.4139088392937 500023.9437197674 0.07320435091763325 0.06508835588231794 1.6854523954847453e-07 6.773283509337167 -0.26660373814989835 AVTIANS(ph)PSKPSEKDSVVSLESQK ddPTM_PC-9_Lapatinib_30min_R1 2 AVTIANSPSKPSEKDSVVSLESQK 24 2 Q8NEF9 Q8NEF9 SRFBP1 Serum response factor-binding protein 1 1 AVT(0.026)IANS(0.74)PS(0.205)KPS(0.027)EKDS(0.001)VVSLESQK;AVT(0.072)IANS(0.514)PS(0.229)KPS(0.179)EKDS(0.005)VVS(0.001)LESQK 58.477 0.0017809999999999998 201772000.0 336260.0 190112.0 206586.0 244540.0 227580.0 229090.0 184350.0 187367.0 202897.0 177402.0 True False 331464.8707374687 189671.80734444613 189601.29652502073 262524.2873615267 214194.1918394948 219292.35473487308 193894.74096852244 196072.75483686215 180044.60325987008 208065.69932669366 1.5930779163028705 0.9115957505645059 0.9112568632820103 1.2617374618260604 1.0294546027174738 1.0539572617904305 0.9318919052778577 0.9423598193808926 0.8653257304904143 1.0 17.666679623604182 -4.756533475787252 24.99674108778484 0.9954186120247682 1.5930788317457465 0.742673790329909 0.10649719766353982 81.79328945846552 416708.08020667883 0.02805205306556402 0.22525704950799708 1.7517274043694982e-05 4.756533475787252 0.5976602197209783 AVTIANSPS(ph)KPSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVTIANSPSKPSEK 14 1 Q8NEF9 Q8NEF9 SRFBP1 Serum response factor-binding protein 1 1 AVT(0.002)IANS(0.103)PS(0.828)KPS(0.067)EK 63.16 0.021490000000000002 54055000.0 70489.0 94882.0 61144.0 68326.0 78724.0 52332.0 73301.0 58564.0 51811.0 53203.0 True False 82421.39547878932 104301.25790670737 62601.90484991131 64497.9157358808 63298.59732496253 49587.617794779144 66357.39862671694 57026.75705368715 52568.637858217975 62848.2827452837 1.3114343284896584 1.6595721211576684 0.9960797990874162 1.0262478610160735 1.0071651055527469 0.7890051347266179 1.055834713824326 0.9073717620067604 0.8364371397588085 1.0 15.939585704804463 -5.324279393134083 6.803283976224448 0.9495527527200273 1.4840030242346074 0.783616252260226 0.11212851765798645 0.08952478902536037 8.138413483016114 0.02827265165373445 0.05985045547519037 4.73936990955989e-06 5.324279393134083 0.5344502715145801 AVTIANSPS(ph)KPSEKDSVVSLESQK ddPTM_PC-9_AZD4547_30min_R2 1 AVTIANSPSKPSEKDSVVSLESQK 24 2 Q8NEF9 Q8NEF9 SRFBP1 Serum response factor-binding protein 1 1 AVT(0.039)IANS(0.412)PS(0.509)KPS(0.035)EKDS(0.003)VVS(0.001)LESQK 48.641000000000005 0.011566 128970000.0 75916.0 56426.0 69117.0 105600.0 97725.0 87526.0 76599.0 75336.0 72572.0 83603.0 True False 100055.70884910562 74664.60102942967 68200.46341975454 81255.55150373628 84157.57060628838 82052.9853836294 83416.1626080746 63694.552249058215 76408.00776132567 80676.08441677275 1.2402152332061347 0.9254861780811307 0.8453615952334879 1.0071826377191289 1.043153881533594 1.0170670276924147 1.0339639462067423 0.7895097129406043 0.9470961352883936 1.0 16.299853444541625 -7.723197227989845 24.99991371865673 0.9012266227391583 1.0067516833052716 0.1602040118077379 0.10661576372017975 282.9247846002679 184955.33802114087 0.05053012555154785 0.029172842165762283 1.8914844357410298e-08 7.723197227989845 0.10552506056611333 AVTIANSPSKPS(ph)EK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVTIANSPSKPSEK 14 1 Q8NEF9 Q8NEF9 SRFBP1 Serum response factor-binding protein 1 1 AVTIANS(0.112)PS(0.216)KPS(0.672)EK 110.92 0.0021651 11997000.0 27195.0 35729.0 22487.0 26075.0 30357.0 19291.0 27843.0 24610.0 20175.0 23554.0 True False 31798.576374266482 39275.9389952651 23023.17536242239 24614.102286290607 24408.763769547866 18279.346000135374 25205.50947413646 23964.01357645039 20470.021207649857 27824.1537466386 1.1428407370020384 1.4115771265823307 0.8274528516506559 0.884630760396952 0.8772508947373344 0.6569596389735187 0.9058859329075374 0.8612665741665352 0.7356924991877898 1.0 14.764050189161829 -5.271628728108317 24.865949565554455 0.8369075271325539 1.2772089298593836 0.7237185561404008 0.10708893357966437 262.7611468379688 641239.6845398623 0.026518980827404434 0.056226549302899116 5.350215459083622e-06 5.271628728108317 0.4403014027268297 AVTKYTS(ph)SK ddPTM_PC-9_Lapatinib_30min_R1 1 AVTKYTSSK 9 1 Q16778;P33778;P23527;Q96A08;A0A2R8Y619;Q8N257;U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880 Q16778;Q8N257;U3KQK0 HIST2H2BE;HIST1H2BB;HIST1H2BO;HIST1H2BA;HIST3H2BB;HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL Histone H2B type 2-E;Histone H2B type 1-B;Histone H2B type 1-O;Histone H2B type 1-A;Histone H2B type 3-B;Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L 1 AVTKYT(0.014)S(0.931)S(0.054)K 89.266 0.045747 4012500.0 21664.0 19637.0 24435.0 18019.0 17634.0 23740.0 13419.0 20425.0 27664.0 16759.0 True False 21355.06738730896 19591.531732993677 22426.04862182766 19344.17736962191 16596.802789777903 22724.695540642944 14113.770160328735 21374.020065128414 24548.189005165434 19655.77082003619 1.086452807311967 0.9967317950727718 1.1409396673961816 0.9841474825247426 0.8443730312962281 1.156133521737974 0.718047147046597 1.087417037002727 1.2489049261879945 1.0 14.262665321100219 -7.9888878349728305 24.99935659330724 1.139022084467813 0.9895809401873777 0.14670021725419446 0.13650324503411165 339.2370359234469 763191.4357328587 0.07205938514277552 0.03456976952132137 1.0259168550916405e-08 7.9888878349728305 -0.1494411442804352 AVTPS(ph)SEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVTPSSEAK 9 0 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5 Q99700 ATXN2 Ataxin-2 1 AVT(0.187)PS(0.407)S(0.407)EAK 87.258 0.011029 11935000.0 99663.0 98928.0 112050.0 138830.0 140120.0 115500.0 131340.0 119560.0 105350.0 96853.0 True False 116533.97746602395 108748.91804762483 114721.69695199144 131051.80519293276 112664.49185983646 109442.97667387054 118898.5243807449 116421.6766842915 106890.54444738118 114411.68221207378 1.0185496377023482 0.9505053675030104 1.00270964235403 1.145440768452428 0.9847289165017369 0.9565716940601114 1.0392166436321975 1.0175680877455502 0.9342625017019556 1.0 16.803874843064904 AVTPVPT(ph)KTEEVSNLK ddPTM_PC-9_AZD4547_30min_R2 2 AVTPVPTKTEEVSNLK 16 1 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YBW1 Q6PKG0 LARP1 La-related protein 1 1 AVT(0.075)PVPT(0.721)KT(0.181)EEVS(0.022)NLK;AVT(0.082)PVPT(0.458)KT(0.458)EEVS(0.002)NLK 60.763999999999996 0.031841 612410000.0 280710.0 211434.0 408170.0 618800.0 508200.0 370060.0 309060.0 427790.0 360970.0 435580.0 True False 369969.9408692823 279775.90568277834 402757.39910646004 476145.22036469675 437645.20217053726 346920.089699813 336565.7412714469 361684.8851362511 380050.1372651398 420330.4767802331 0.8801882359406419 0.6656093743805717 0.9581922352897551 1.1327877626481175 1.04119312385563 0.8253507867363084 0.8007169593068029 0.860477422210228 0.9041698336422234 1.0 18.68116453979097 -1.5231171041219114 0.01093801737135091 1.6929392502674458 7.1060729079397455e-06 0.03942495843327776 0.12373243137013494 60028.58098894754 50.938365224987244 3350.5875368172683 4628.821850851495 0.029983539272116885 1.5231171041219114 -1.692932144194538 AVTPVPT(ph)KTEEVSNLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVTPVPTKTEEVSNLK 16 1 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YBW1 Q6PKG0 LARP1 La-related protein 1 1 AVT(0.247)PVPT(0.515)KT(0.238)EEVSNLK 72.615 0.011507 56750000.0 118100.0 59424.0 105100.0 145140.0 173110.0 165780.0 140030.0 197220.0 140360.0 107010.0 True False 138091.9974186749 65323.222000465554 107605.98259396983 137008.27635022908 139190.33818053245 157086.2049609892 126765.34467059337 192043.1839718629 142412.49946496793 126410.06590930608 1.0924129848785153 0.5167564903204166 0.8512453642036119 1.083839924967105 1.1011016977112857 1.24267164826646 1.002810525876493 1.5192080044451983 1.1265914501392866 1.0 16.947751822914128 -5.833520308759561 2.5404982565251655 1.18412640343402 0.7783847515289759 0.39620847565615847 0.18988179851590026 0.24655602713479868 3.2363115994032086 0.05479893161508019 0.09411479800053439 1.4671674766687322e-06 5.833520308759561 -0.4057416519050441 AVTPVPTKT(ph)EEVSNLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVTPVPTKTEEVSNLK 16 1 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YBW1 Q6PKG0 LARP1 La-related protein 1 1 AVT(0.212)PVPT(0.143)KT(0.64)EEVS(0.005)NLK 56.527 0.044119 56022000.0 82141.0 53258.0 61583.0 111420.0 116930.0 113220.0 112300.0 127520.0 107820.0 76010.0 True False 96045.8489412989 58545.10227013992 63051.372274828085 105177.49862851358 94018.4058890283 107282.54388758099 101662.13101840757 124172.73511860872 109396.66352459995 89790.01130517088 1.0696718660037385 0.6520224401260143 0.7022092029873377 1.171371927675173 1.047092037548434 1.1948160193783464 1.132220940176594 1.3829237051388787 1.2183611733023576 1.0 16.454267340751713 -5.77012711837263 24.994343262928073 1.1748921496439024 0.7923732918900421 0.5704682655520619 0.14108134742164852 120.85364449382106 347692.5592032981 0.03987344952824305 0.06018024182916672 1.6977466478078227e-06 5.77012711837263 -0.3825188577538603 AVTT(ph)PGK ddPTM_PC-9_AZD4547_30min_R2 1 AVTTPGK 7 0 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 1 AVT(0.096)T(0.904)PGK 98.58200000000001 0.029625 18389000.0 437840.0 365420.0 354810.0 455210.0 402400.0 429230.0 342180.0 387870.0 561610.0 693670.0 True False 577064.0123622471 483534.86882242566 350104.9875712647 350268.36742439185 346533.7059296033 402390.180246044 372633.3571095057 327933.60386591085 591295.5580504612 669384.8244367155 0.8620811098426739 0.722357082458985 0.523024984717687 0.5232690593473511 0.5176898150047097 0.6011343035520019 0.5566803182654687 0.4899029555112272 0.8833417437391623 1.0 19.352476318622195 -8.418884307711055 4.408259804694123 0.9957046916623963 0.5952917761944369 0.6207443262007017 0.10849191713078024 0.14204511815303153 4.276637551615957 0.11187830643680112 0.029277220716777002 3.811673495513007e-09 8.418884307711055 -0.40041291546795943 AVTT(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AVTTPGK 7 0 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 1 AVT(0.038)T(0.962)PGK;AVT(0.126)T(0.874)PGK 93.162 0.034475 43971000.0 421270.0 613920.0 546580.0 540580.0 1019520.0 892230.0 553870.0 658830.0 736090.0 741360.0 True False 492582.69053823286 674865.9203440668 559612.5401161944 510293.0551840068 819752.3746855551 845439.8881188532 501403.4239284543 641536.4105880877 746853.9237045347 875762.6993974693 0.5624613732431549 0.7706036359031724 0.6390002000555763 0.5826841626562674 0.9360439480347249 0.9653755391734788 0.5725334320283603 0.7325459408461552 0.8528039892751487 1.0 19.740180478074954 -14.52287874512995 0.038439602323378466 2.2354333639810755 6.939752435263521e-08 0.3437691363115073 0.13074128048054828 1223.0932184838216 3.5035779608638586 179.65893072744265 56.39484314486113 3.0000000010388456e-15 14.52287874512995 -2.2354332945835513 AVTT(ph)PGK ddPTM_PC-9_Lapatinib_30min_R1 3 AVTTPGK 7 0 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 1 AVT(0.138)T(0.862)PGK;AVT(0.034)T(0.966)PGK;AVT(0.045)T(0.955)PGK 101.72 0.027159 97514000.0 807600.0 1162730.0 983850.0 1039060.0 1215160.0 719690.0 1147600.0 1090890.0 1102410.0 772560.0 True False 796083.4759042965 1160037.7701229162 902961.6507708256 1115475.9386025497 1143686.6778964803 688910.5363793314 1207017.1127500746 1141576.731889738 978244.9769080537 906095.9666285081 0.8785862703554934 1.2802592803048225 0.9965408566276429 1.2310792451191714 1.2622136285983299 0.7603063712364797 1.3321073674362152 1.2598850165258213 1.0796262348987216 1.0 19.78930433182419 AVTTVTQSTPVPGPSVPPPEELQVS(ph)PGPR ddPTM_PC-9_AZD4547_30min_R2 4 AVTTVTQSTPVPGPSVPPPEELQVSPGPR 29 0 P51610;P51610-2;H7C1C4 P51610 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 AVTTVTQSTPVPGPSVPPPEELQVS(1)PGPR;AVTTVTQSTPVPGPSVPPPEELQVS(1)PGPR;AVTTVTQSTPVPGPSVPPPEELQVS(1)PGPR;AVTTVTQSTPVPGPSVPPPEELQVS(1)PGPR 125.96 2.0801e-13 106464000.0 65801.6 64445.0 90134.0 109534.0 99414.0 96649.0 78220.0 106939.0 82133.4 94678.0 True False 86725.14004169469 85275.58595933799 88938.76426749062 84282.62858343043 85612.08211055069 90605.52275143834 85181.42846778141 90414.03476375209 86474.80384534068 91363.35203774042 0.9492333425536994 0.9333675271033434 0.9734621408237272 0.9224993030970987 0.9370505810161825 0.9917053252819683 0.9323369443865701 0.9896094303370547 0.946493335857682 1.0 16.479327962381447 -14.009642207886095 0.12069114216966517 1.1407441544309154 0.9287803178302719 0.31551233481239616 0.022369151550545086 154.2229461001848 1.3546593466728236 5.377896560345426 0.20882567612269504 9.780426464293193e-15 14.009642207886095 -0.21196383660064344 AVTTVTQSTPVPGPSVPPPEELQVS(ph)PGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 AVTTVTQSTPVPGPSVPPPEELQVSPGPR 29 0 P51610;P51610-2;H7C1C4 P51610 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 AVTTVTQSTPVPGPSVPPPEELQVS(1)PGPR;AVTTVTQSTPVPGPSVPPPEELQVS(1)PGPR;AVTTVTQSTPVPGPSVPPPEELQVS(1)PGPR;AVTTVTQSTPVPGPSVPPPEELQVS(1)PGPR 190.83 6.7149e-26 75947000.0 111907.0 107899.0 127482.0 130902.0 156532.0 140253.0 133396.0 129099.0 128100.0 106737.0 True False 130850.64483600075 118610.49964035135 130521.65435817704 123567.98533000992 125860.67827436377 132897.88577870428 120759.76517659375 125710.2880416973 129973.22015860974 126087.57317037298 1.0377759008747973 0.9406993620226285 1.0351666788115004 0.9800171596850505 0.9982004975565465 1.0540125599778896 0.9577451777378556 0.9970077532687073 1.0308170495357727 1.0 16.944066569223324 -6.546463268768161 24.99903853679945 1.0069840740723548 0.9959412730970508 0.01638183533726012 0.0345636760889352 1206.4339514601677 1278782.3397445672 0.010990578737709018 0.010991207118553963 2.8414284937129796e-07 6.546463268768161 -0.011042800975303968 AVTTVTQSTPVPGPSVPPPEELQVS(ph)PGPR ddPTM_PC-9_Lapatinib_30min_R1 4 AVTTVTQSTPVPGPSVPPPEELQVSPGPR 29 0 P51610;P51610-2;H7C1C4 P51610 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 AVTTVTQSTPVPGPSVPPPEELQVS(1)PGPR;AVTTVTQSTPVPGPSVPPPEELQVS(1)PGPR;AVTTVTQSTPVPGPSVPPPEELQVS(1)PGPR;AVTTVTQSTPVPGPS(0.001)VPPPEELQVS(0.999)PGPR 128.63 1.0601e-13 81634000.0 72524.7 68877.0 83122.0 75843.0 82498.0 83410.0 67663.0 75610.0 84824.0 62567.5 True False 71490.48447859877 68717.51953829011 76288.03002019874 81420.74722483115 77645.62983730847 79842.74873820666 71166.25906239824 79123.11662787577 75270.22788368116 73382.20900904675 0.9742209377995861 0.9364329646960946 1.0395984401449914 1.1095434210054018 1.0580988346608116 1.088039591835719 0.9698026268686553 1.0782329626806584 1.0257285641864726 1.0 16.163142713931883 -5.314561357718545 6.214939584691751 1.0507819309397755 0.955446667709476 0.4461696699705149 0.04026288122949293 0.1650882007200228 14.765526588011932 0.010413560744591958 0.022350702314726925 4.846616341283957e-06 5.314561357718545 -0.0953352632302995 AVVGVVAGGGR ddPTM_PC-9_Lapatinib_30min_R1 2 AVVGVVAGGGR 11 0 E9PKU4;P62917;E9PKZ0;E9PP36 E9PKU4 RPL8 60S ribosomal protein L8 0 ; 124.59 0.0023203000000000004 10873900.0 58037.0 52603.0 51788.0 47214.0 54767.0 53271.0 50575.0 44747.0 60944.0 47551.0 False True 57209.38173731766 52481.20098541866 47530.19054746107 50686.27506128689 51545.7127360648 50992.7235107662 53193.52603462444 46826.108976954754 54079.84495122909 55770.12699227521 1.025806911740434 0.9410271020664503 0.8522517898165183 0.9088427406361744 0.9242530995707516 0.9143375900476121 0.9537996218296642 0.8396270817787576 0.9696919814925248 1.0 15.76720493564396 -8.513434724167695 24.33740695997443 1.0000000180069661 0.9182396485789972 0.2296727697591726 0.0490188928206157 521.3914965959325 1343633.129922026 0.04710643426144512 0.012162828992694993 3.0659514669849923e-09 8.513434724167695 -0.08176036942796894 AVVIVDDR ddPTM_PC-9_AZD4547_30min_R2 4 AVVIVDDR 8 0 Q15233;Q15233-2;H7C367;C9IZL7;P23246;P23246-2 Q15233;P23246 NONO;SFPQ Non-POU domain-containing octamer-binding protein;Splicing factor, proline- and glutamine-rich 0 ;;; 117.17 0.016395 30155900.0 170427.0 157303.0 203234.0 281428.0 245278.0 224562.0 173326.0 235504.0 183961.0 194712.0 False True 224619.24089818305 208148.11852217742 200538.98436926326 216549.1226192566 211225.3835064646 210520.10264057005 188751.67822304624 199112.26814354653 193684.80289617513 187895.1921457202 1.1954496458003134 1.1077884226050354 1.0672917283255299 1.1524995405487233 1.1241659836758935 1.1204123971267095 1.0045583182174336 1.0596985791372833 1.0308129797486507 1.0 17.519568626046997 -7.249681618868217 22.898190067158588 1.028742354504069 1.1252076938529185 0.6881912516951105 0.03425509234477046 149.72443969340114 291588.0474488126 0.01325486193436159 0.010161312826172768 5.627537285657797e-08 7.249681618868217 0.09646533934884949 AVVIVDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AVVIVDDR 8 0 Q15233;Q15233-2;H7C367;C9IZL7;P23246;P23246-2 Q15233;P23246 NONO;SFPQ Non-POU domain-containing octamer-binding protein;Splicing factor, proline- and glutamine-rich 0 ;; 112.17 0.017205 12144600.0 103350.0 98586.0 108460.0 118696.0 135195.0 124551.0 131712.0 111378.0 114796.0 101298.0 False True 120845.11374445473 108372.96654782376 111046.09773684034 112045.84793762401 108704.51025542803 118019.32630049555 119235.28584769795 108454.44551474562 116474.67432730494 119662.5255254735 1.0098826948018031 0.9056550166555992 0.9279939333488418 0.9363486809725735 0.9084256727665944 0.9862680549506859 0.9964296284413235 0.9063359229507326 0.9733596530394979 1.0 16.86861189151964 -6.7708674260550525 24.99848497867939 0.968121580799103 0.9352730885933861 0.18037268602169365 0.03634629584724734 379.5786449660749 1006448.9805762239 0.01263473538243019 0.011289500434570722 1.6948550976821847e-07 6.7708674260550525 -0.03284849220571695 AVVIVDDR ddPTM_PC-9_Lapatinib_30min_R1 5 AVVIVDDR 8 0 Q15233;Q15233-2;H7C367;C9IZL7;P23246;P23246-2 Q15233;P23246 NONO;SFPQ Non-POU domain-containing octamer-binding protein;Splicing factor, proline- and glutamine-rich 0 ;;;; 112.17 0.017205 51469300.0 399296.0 367652.0 419814.0 354099.0 376718.0 392585.0 337805.0 318184.0 380935.0 308039.0 False True 393601.96581808216 366800.7243824717 385298.51344890345 380140.6216996359 354560.1878960842 375795.0547103329 355294.89000744035 332967.99022779946 338030.0888766158 361283.13071383245 1.089455699302631 1.0152722150567546 1.0664724718467224 1.0521958801357383 0.9813914842786463 1.0401677320715954 0.9834250752462192 0.9216261760406936 0.9356376208563276 1.0 18.46277036744776 -7.048551189491519 0.9944011985243136 0.9470793664104037 1.0518471908138054 0.5914748333080868 0.03331272714609128 0.36817918892490925 0.7441833388734348 0.022006712220489378 0.015135153629022308 8.942291245789821e-08 7.048551189491519 0.10476782440340171 AVVLPGGTAT(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AVVLPGGTATSPK 13 0 Q8N1G0;Q8N1G0-2;F8WCX2;H0Y5I5 Q8N1G0 ZNF687 Zinc finger protein 687 1 AVVLPGGTAT(0.6)S(0.399)PK;AVVLPGGTAT(0.624)S(0.376)PK;AVVLPGGT(0.003)AT(0.595)S(0.402)PK 156.0 0.00048425 25508000.0 270499.0 312420.0 214605.0 311672.0 318592.0 242187.0 321093.0 291149.0 228381.0 224049.0 True False 316289.13810122106 343434.99288815 219721.9970939951 294210.0282942581 256166.1846318077 229486.2873741532 290676.74652799254 283506.6472478652 231720.640070596 264667.3101290923 1.1950442158759615 1.297610168481474 0.8301818497600819 1.1116220894479045 0.9678799565645709 0.8670745444997365 1.0982721907976245 1.071181201447145 0.8755166626266521 1.0 18.013820488586113 -5.246862757303941 24.990884331455103 0.9850434075257123 1.2463272257534896 0.5557572742417665 0.09588310674677573 578.735090640557 992208.1746158976 0.023708371701068057 0.06212215391050834 5.664182562833091e-06 5.246862757303941 0.26128381822777735 AVVLPGGTAT(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 1 AVVLPGGTATSPK 13 0 Q8N1G0;Q8N1G0-2;F8WCX2;H0Y5I5 Q8N1G0 ZNF687 Zinc finger protein 687 1 AVVLPGGT(0.065)AT(0.656)S(0.279)PK 119.74 0.00054586 3438300.0 37950.0 43616.0 39017.0 42354.0 47537.0 42785.0 36503.0 42904.0 37298.0 34757.0 True False 37408.82604082236 43515.00983175908 35809.17286997547 45468.854448802165 44740.967121337875 40955.18528670633 38392.94672944925 44897.476468752495 33097.10647464794 40764.70113920865 0.9176769360597982 1.0674678978550172 0.8784358003187515 1.115397713662346 1.0975418896988978 1.0046727718387334 0.9418184276229569 1.1013812247863832 0.8119060253041865 1.0 15.31503281768534 -9.856283277914898 7.7801218534631635 0.9999999999883467 1.000459170377692 0.0 0.09902663004051286 0.0 0.0 0.09094933233780388 0.02205845316518644 1.3922483827626206e-10 9.856283277914898 0.000459170389345287 AVVLPGGTATS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 AVVLPGGTATSPK 13 0 Q8N1G0;Q8N1G0-2;F8WCX2;H0Y5I5 Q8N1G0 ZNF687 Zinc finger protein 687 1 AVVLPGGTAT(0.33)S(0.67)PK;AVVLPGGT(0.004)AT(0.23)S(0.766)PK 154.23 5.1821000000000004e-05 41384000.0 177729.0 160266.0 160197.0 169754.0 188904.0 151061.0 161418.0 154173.0 155844.0 165916.0 True False 234243.1250071479 212068.8503275545 158072.68310913982 130619.8379731559 162677.94032039196 141615.13178982705 175783.8892918995 130349.10539309325 164081.59567816838 160107.3313409002 1.4630380947915367 1.3245417842610716 0.9872919733611186 0.8158267137376765 1.0160555357332042 0.884501231791194 1.0979128052395104 0.8141357694330326 1.0248225006561766 1.0 17.288679845045493 -5.1942108834402365 3.020943270512105 0.9448789572248882 1.4402736846766948 0.8051834756164784 0.0875925804182376 0.09912771694989148 1.7431672668143396 0.02187482293043049 0.07268226956768015 6.394242703260747e-06 5.1942108834402365 0.49539472745180657 AVVLPGGTATS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVVLPGGTATSPK 13 0 Q8N1G0;Q8N1G0-2;F8WCX2;H0Y5I5 Q8N1G0 ZNF687 Zinc finger protein 687 1 AVVLPGGT(0.001)AT(0.023)S(0.977)PK 139.32 6.792899999999999e-05 9223900.0 114410.0 122030.0 97411.0 138140.0 133480.0 105480.0 113220.0 112080.0 101940.0 95350.0 True False 133777.35329949716 134144.33193182593 99733.64767327458 130400.46365592263 107325.5521941976 99948.44311307238 102494.9819581842 109138.01875857635 103430.67964846716 112636.20020981514 1.1876941254259372 1.1909522132489032 0.8854493270147067 1.1577136250425422 0.9528513212828111 0.8873563110873023 0.9099648404976357 0.9689426539183451 0.918272095967369 1.0 16.781311044926277 -4.6115892552017375 0.639502371427678 0.9362203187254831 1.4509466624558611 0.5207966259327879 0.0819071994379574 3.1985309038580123 0.8501228871277262 0.037727995498702135 1.2669440662275537 2.4457425810139976e-05 4.6115892552017375 0.5147263437303781 AVVLPGGTATS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 AVVLPGGTATSPK 13 0 Q8N1G0;Q8N1G0-2;F8WCX2;H0Y5I5 Q8N1G0 ZNF687 Zinc finger protein 687 1 AVVLPGGTAT(0.146)S(0.854)PK;AVVLPGGTAT(0.215)S(0.785)PK;AVVLPGGTAT(0.123)S(0.876)PK 154.23 2.5550999999999998e-08 31805000.0 214479.0 212174.0 197898.0 207879.0 223725.0 191096.0 189844.0 191290.0 177404.0 177470.0 True False 211420.49012936887 211682.72413893216 181627.59034837113 223167.11512401476 210565.9353602736 182923.26954653347 199673.19340617393 200178.03173847825 157422.89337306138 208145.4530360895 1.0157343677006077 1.0169942271197698 0.872599365967795 1.0721690619171043 1.0116288023056859 0.8788242398685363 0.9592964462766977 0.9617218575693326 0.7563119495373577 1.0 17.667232517402404 -6.754133109659469 24.997823901146983 0.9118426095413841 0.9960633500651831 0.23821198144070654 0.07739141253897104 264.81123301464856 906029.8759653441 0.02541944241260023 0.024927245336199753 1.7614360899932132e-07 6.754133109659469 0.08422074052379902 AVVMPLQLIQEQAAS(ph)PNAEIHILK ddPTM_PC-9_AZD4547_30min_R2 1 AVVMPLQLIQEQAASPNAEIHILK 24 0 H3BRB3;Q14807-2;Q14807;I3L306 H3BRB3 KIF22 Kinesin-like protein;Kinesin-like protein KIF22 1 AVVMPLQLIQEQAAS(1)PNAEIHILK 80.664 8.3681e-05 1704900.0 7323.5 7147.1 10678.0 13869.0 10918.0 8545.8 7085.0 9750.6 8019.2 8637.0 True False 9652.220661736972 9457.260305841935 10536.402743118744 10671.716323914008 9402.22415839813 8011.429775054489 7715.551274536336 8243.868816497657 8443.07854047873 8334.621258898202 1.158087495749381 1.134695868242985 1.2641729498949792 1.2804080704351957 1.1280925510994437 0.9612230149631974 0.9257230814536491 0.9891113897582743 1.0130128626378476 1.0 13.024900926546357 -6.625880385507323 3.8199218343646155 0.9739908018809134 1.2079195757007963 0.8469269615654764 0.046662532037161183 0.09155612892568718 2.5351908762230515 0.01768195172941287 0.01766821582903144 2.3665714148613059e-07 6.625880385507323 0.23392877381988297 AVVMPLQLIQEQAAS(ph)PNAEIHILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVVMPLQLIQEQAASPNAEIHILK 24 0 H3BRB3;Q14807-2;Q14807;I3L306 H3BRB3 KIF22 Kinesin-like protein;Kinesin-like protein KIF22 1 AVVMPLQLIQEQAAS(1)PNAEIHILK 46.415 0.032751999999999996 5149300.0 1150.9 2884.4 3940.7 3168.6 4265.5 2526.4 4317.2 3227.6 3219.0 3038.3 True False 1345.724638688851 3170.7441696644923 4034.6612331879724 2991.0736147398034 3429.705895147957 2393.911136526981 3908.2435621787145 3142.878919924878 3266.071785250305 3589.1197388304354 0.3749455957486038 0.8834322620559111 1.1241367039213697 0.8333724791568214 0.9555841389302812 0.6669911595947674 1.0889142315024212 0.8756684503785959 0.9099924279245696 1.0 11.809414339255277 -4.765919574122232 5.221803508007757 0.9259216890525925 0.34563729290156503 0.6463029313410207 0.12277299554885843 0.09541316134877138 7.436230354234044 0.0295214360588473 0.20098166268019807 1.714274740243971e-05 4.765919574122232 -0.5802843961510276 AVVPSKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVVPSKR 7 1 B4DY08;B2R5W2;G3V4W0;G3V576;G3V5V7;G3V555;G3V575;P07910-2;P07910;G3V4C1;G3V2Q1;G3V2D6;P07910-3 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 0 71.715 0.025756 4837600.0 26167.0 18354.0 23598.0 33760.0 37656.0 27639.0 29698.0 29780.0 33472.0 24966.0 False True 30596.556278191983 20176.063822639746 24160.665815913373 31868.536651396756 30277.5771158578 26189.562184321272 26884.790445099454 28998.306554518185 33961.46467719734 29492.13816925274 1.0374478819609851 0.6841166858384808 0.819223946302485 1.0805773548362645 1.02663214657742 0.8880184283018654 0.9115917703494419 0.9832554828035696 1.1515429801086492 1.0 14.848042800604713 -5.745390211636951 24.98692391213966 0.9972646788702124 0.8306481433167395 0.30962197040714934 0.10744845704249571 284.9503986662411 443635.21688274934 0.02934145954981848 0.050614303615252966 1.7972553636009935e-06 5.745390211636951 -0.1666165355534729 AVVQLKPR ddPTM_PC-9_Lapatinib_30min_R1 1 AVVQLKPR 8 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 102.77 0.0054135 4443100.0 23274.0 29396.0 27735.0 26549.0 28773.0 23668.0 30230.0 23100.0 25209.0 22712.0 False True 22942.108492071133 29327.935368084854 25454.735360196035 28501.502024867743 27080.62870989451 22655.774812802734 31795.16148347399 24173.31033069601 22369.696957461532 26637.73893816228 0.8612633581750198 1.1009919211299308 0.9555891894311109 1.0699670152572658 1.0166264025922158 0.8505141846084081 1.193613375267485 0.9074835663346924 0.8397746148571873 1.0 14.701184008462384 -7.93938232055758 24.99998409321011 0.904451586423852 1.0085886905649617 0.13493901820333154 0.10460318223355157 114.55888675730652 47245.77935051365 0.05351970593226399 0.02571002989714025 1.1497877556713244e-08 7.93938232055758 0.10413710414110966 AVVQS(ph)PQVTEVL ddPTM_PC-9_AZD4547_30min_R2 1 AVVQSPQVTEVL 12 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 AVVQS(0.988)PQVT(0.012)EVL 88.021 0.0082618 2652700.0 17768.0 16815.0 23128.0 31888.0 26240.0 23257.0 16977.0 26137.0 19245.0 22683.0 True False 23417.854402641155 22250.11991475314 22821.30760843326 24536.714264688846 22597.028935369748 21802.736113464198 18487.920111193125 22098.127218509573 20262.251410553814 21888.875074167863 1.0698518915792852 1.0165035818131924 1.0425984675368634 1.120967349009444 1.0323522272753802 0.9960647150476306 0.8446263249504141 1.0095597486683388 0.9256871968932882 1.0 14.417910192148627 -6.861604000374022 3.2779387405986413 0.9434615417715392 1.0581162122421417 0.5255657669073285 0.04970645835255742 0.19092900780130645 4.063601285809447 0.018141256495553218 0.0159884175753194 1.3752954292396627e-07 6.861604000374022 0.11465467047060252 AVVQS(ph)PQVTEVL ddPTM_PC-9_Lapatinib_30min_R1 2 AVVQSPQVTEVL 12 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 AVVQS(1)PQVTEVL;AVVQS(1)PQVTEVL 94.402 0.00492 3653400.0 36559.0 37484.0 43984.0 38219.0 37940.0 34575.0 33543.0 32146.0 42505.0 24230.7 True False 36037.66195590051 37397.208101010096 40367.805303149944 41029.75275484651 35708.44379290994 33096.307848261546 35279.692412840486 33639.62051474261 37717.63930250713 28418.94420962173 1.2680858827858683 1.3159253146479881 1.4204540818051472 1.4437465534330147 1.2565014213589334 1.1645861156607011 1.2414146054340727 1.1837040907154224 1.327200582269948 1.0 14.794565337654547 -6.4776117994350075 5.8343686629878055 1.1993740902147096 1.362431574118605 0.46412842813693844 0.08967115515045153 0.19882486111401854 16.970762959924123 0.027874527947336233 0.030989005397958652 3.329570389065591e-07 6.4776117994350075 0.1630574839038954 AVVS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 1 AVVSPPK 7 0 P49792;J3KQ37;F8VYC4;A0A286YES2;A0A1W2PNU4;J3KNE0;P0DJD0;P0DJD1;Q7Z3J3;A6NKT7;H7BZ48;Q99666;O14715 P49792;Q99666 RANBP2;RGPD8;RGPD1;RGPD3;RGPD2;RGPD4;RGPD6;RGPD5 E3 SUMO-protein ligase RanBP2;RANBP2-like and GRIP domain-containing protein 1;RANBP2-like and GRIP domain-containing protein 2;RanBP2-like and GRIP domain-containing protein 4;RanBP2-like and GRIP domain-containing protein 3;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8 1 AVVS(1)PPK 70.816 0.043012 38496000.0 165190.0 235410.0 180530.0 208060.0 211740.0 194000.0 231650.0 225290.0 171120.0 159240.0 True False 162834.3603078639 234864.92260854755 165687.5202659524 223361.42646781306 199285.86949685664 185703.07223608813 243643.70352784503 235757.79586158044 151846.66362651478 186764.42182603732 0.8718703418766601 1.2575463801521776 0.8871471270919196 1.1959527638292062 1.0670440737502054 0.994317174654722 1.3045509479037085 1.2623271261010207 0.8130384906390423 1.0 17.510860125716704 AVVVCPK ddPTM_PC-9_Lapatinib_30min_R1 1 AVVVCPK 7 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PRZ7;A0A1W2PQ74;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7;A0A1W2PQD4 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 126.05 2.5926999999999998e-05 0.0 49708.0 45954.0 55508.0 47378.0 50673.0 48372.0 46697.0 39691.0 48215.0 48359.0 False True 48999.1548046692 45847.59633640535 50944.346507076334 50862.33616837484 47692.51376695113 46303.24232063942 49114.742169824196 41535.18875911928 42784.518973541504 56717.788715682946 0.8639115860157031 0.8083459770660648 0.8982075581693084 0.8967616213555056 0.8408739982093792 0.8163795410422301 0.8659495245138772 0.7323132600836826 0.7543403920067008 1.0 15.791513666162377 -6.526261257108124 5.342276510412434 0.8197245952777531 0.8654599478447418 0.027473975212558455 0.0720345303618682 0.47875921387993603 44.058533527703446 0.0231998442257073 0.02433262983753057 2.9767251918909785e-07 6.526261257108124 0.045735352566988685 AVVVS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 AVVVSPK 7 0 G3V5E1;O75909-1;O75909 G3V5E1 CCNK Cyclin-K 1 AVVVS(1)PK;AVVVS(1)PK 76.679 0.030904 54355000.0 455730.0 555670.0 415110.0 335760.0 415870.0 482670.0 511830.0 474100.0 528000.0 394760.0 True False 600642.6602271299 735279.4607809029 409605.3701719445 258355.71944028884 358133.62893872836 452488.56859809026 557381.8784539076 400838.73873418476 555909.0020666358 380939.572555592 1.5767399963139188 1.930173480922885 1.075250248809919 0.6782065662201214 0.9401323851342972 1.1878224295850934 1.46317662592685 1.0522370675356623 1.4593101954129741 1.0 18.539202639377315 -5.269591719975766 24.81286087676739 1.1032136066069593 1.7534567466447568 0.54986400447925 0.2339347266512506 376.0845195878995 1144671.892712958 0.06535876481264885 0.13994985125867465 5.375368970774588e-06 5.269591719975766 0.6502431400377975 AVVVS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVVVSPK 7 0 G3V5E1;O75909-1;O75909 G3V5E1 CCNK Cyclin-K 1 AVVVS(1)PK 89.08 0.01684 19333000.0 266890.0 363100.0 233410.0 223970.0 247870.0 190760.0 275680.0 174960.0 183410.0 202840.0 True False 312069.20568221965 399146.16835569916 238975.37961235383 211421.6870205371 199301.65284968284 180756.20978621257 249565.59464964058 170367.48538544317 186092.0242723694 239613.28631944396 1.3023869021443994 1.6657931389646383 0.9973377657103718 0.8823454252811223 0.8317637803438868 0.7543663899556671 1.0415348768136694 0.7110101781180668 0.7766348316106232 1.0 17.870348380792798 -5.406566405896422 4.363466551004917 0.8522790800692059 1.4792632879690428 0.7873945082965406 0.12813071597946485 0.08792056047578282 2.704633489858884 0.0328122633675812 0.07166902251523397 3.921331825350143e-06 5.406566405896422 0.6269842078998369 AVVVS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 AVVVSPK 7 0 G3V5E1;O75909-1;O75909 G3V5E1 CCNK Cyclin-K 1 AVVVS(1)PK 76.221 0.031573000000000004 71092000.0 448290.0 382550.0 275580.0 296990.0 340830.0 266150.0 361920.0 323090.0 252060.0 262050.0 True False 441897.30239368277 381664.22897880175 252922.87616956283 318831.6353295977 320783.0494975616 254767.3849259527 380658.44671183964 338101.94089803385 223670.34849052943 307344.99334032374 1.43778916842276 1.2418104646207273 0.8229282456197385 1.0373737729202401 1.04372303583406 0.8289296733194162 1.2385379783634078 1.1000730391714983 0.7277500962667669 1.0 18.229499458150634 -5.031109046352128 4.379267149560979 0.9878743617443004 1.4072596587413237 0.529182620388913 0.14264213406472048 0.14573465734995172 6.5535343697036 0.03634316860300576 0.1256581191051027 9.30874114332115e-06 5.031109046352128 0.4193852969970233 AVVVS(ph)PKEENK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AVVVSPKEENK 11 1 G3V5E1;O75909-1;O75909 G3V5E1 CCNK Cyclin-K 1 AVVVS(1)PKEENK 106.79 0.011539 16263000.0 38751.0 32687.0 28679.0 54572.0 43730.0 37547.0 36589.0 37682.0 40422.0 33217.0 True False 45310.778932862704 35931.949339142695 29362.81612571318 51514.507764811155 35161.420418431604 35577.96922228413 33123.02503857986 36692.88742737925 41013.0952790891 39238.97915437267 1.1547389842789377 0.9157207988969446 0.7483073402647653 1.3128401623840549 0.8960839750723567 0.9066996641863309 0.8441357484930576 0.9351132016718207 1.0452131060223755 1.0 15.259999888280868 AVVVS(ph)PKEENK ddPTM_PC-9_Lapatinib_30min_R1 1 AVVVSPKEENK 11 1 G3V5E1;O75909-1;O75909 G3V5E1 CCNK Cyclin-K 1 AVVVS(1)PKEENK 54.023 0.042948 71977000.0 132560.0 150070.0 166850.0 170200.0 144440.0 159980.0 165930.0 120230.0 115110.0 143610.0 True False 130669.67009147353 149722.52213527332 153132.23705962524 182717.07577055585 135944.32317996598 153138.02833159466 174521.04349827438 125816.32472119416 102145.09963796254 168432.79715170333 0.7757970674427649 0.8889154883559992 0.9091592590586901 1.0848069904460889 0.8071131363894897 0.9091936423383562 1.0361464420797306 0.7469823386467569 0.6064442398707119 1.0 17.361813561066278 -7.790617081099436 24.949862041754916 0.7575347630185035 0.9166378834199658 0.17833921114389606 0.1253012156856337 297.2409075847594 254166.65367843077 0.06632423428828206 0.03186923548964231 1.6195073333697372e-08 7.790617081099436 0.15910312040146224 AWGPGLEGGVVGK ddPTM_PC-9_Lapatinib_30min_R1 2 AWGPGLEGGVVGK 13 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 175.86 0.00073597 12123100.0 52420.0 57719.0 63656.0 51114.0 54591.0 58713.0 54133.0 47520.0 52172.0 46549.0 False True 51672.48118734936 57585.35520174476 58422.44939926593 54873.09407130551 51380.06471003546 56201.981856687795 56935.74186519674 49727.95268028896 46295.83996448421 54594.932627356284 0.9464702803105476 1.05477472780853 1.070107546391435 1.0050950048028788 0.9411141700775737 1.0294358679824849 1.0428759433374137 0.9108528994753519 0.8479878577830942 1.0 15.736479429363943 -7.77170504293188 24.885331849741032 0.9095652251460228 1.0142364585153503 0.39205172457124604 0.05273589299283882 187.60510442240363 454771.8513687918 0.028403507375309955 0.01388453233096158 1.6915894077999244e-08 7.77170504293188 0.10467123336932749 AWGPGLHGGIVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AWGPGLHGGIVGR 13 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 106.16 0.00096469 4259400.0 36309.0 38508.0 44297.0 44743.0 51931.0 44640.0 48599.0 45623.0 36908.0 31637.0 False True 42455.39656456118 42330.81974949394 45353.20847730802 42236.1947687632 41755.49333980269 42298.99981577127 43995.35089370963 44425.44459156427 37447.709676923965 37372.53766164577 1.136005185115695 1.132671806574609 1.2135437226103207 1.1301398677058219 1.1172774436094823 1.1318203810168708 1.1772106912306528 1.1887189731072683 1.0020114238952347 1.0 15.189690908148288 -8.270088928071218 24.9029447132118 1.00100567058135 1.1528276043095729 0.8142214661771872 0.029120950925737386 277.6107302162218 799259.2826059981 0.027893375612970887 0.007663714019407178 5.369218426069226e-09 8.270088928071218 0.15182193372822295 AWGPGLHGGIVGR ddPTM_PC-9_Lapatinib_30min_R1 2 AWGPGLHGGIVGR 13 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 104.07 0.0011583 11481800.0 61329.0 62804.0 61637.0 62708.0 65421.0 75983.0 61908.0 45328.0 59234.0 56240.0 False True 60454.4372136388 62658.58119666629 56569.44378570049 67319.75550775576 61573.06540263474 72733.38421502411 65113.29332182958 47434.10435799952 52562.44315832739 65961.00906491051 0.9165177742224525 0.9499336363245385 0.857619441965055 1.02059923676286 0.9334767050340648 1.102672400651862 0.9871482296117284 0.7191233886570906 0.7968714230342059 1.0 16.00932584869789 -7.740610762999441 24.997394197698696 0.8184980281301685 0.968007864343746 0.29143389064853775 0.08994925260473564 245.67322293091297 294844.49000757025 0.042144797390046104 0.024298493415583995 1.8171435504628065e-08 7.740610762999441 0.1495098362135775 AWIY(ph)S(ph)MLY(ph)NSK ddPTM_PC-9_Lapatinib_30min_R1 1 AWIYSMLYNSK 11 0 Q8IZU8 Q8IZU8 DSEL Dermatan-sulfate epimerase-like protein 3 AWIY(0.974)S(0.593)MLY(0.84)NS(0.593)K 65.5 0.018473 0.0 562.25 2130.7 2057.8 850.75 980.72 2519.6 1134.6 2518.3 2202.7 1263.8 True False 554.2322118959777 2125.7664950598187 1888.6156273377114 913.3169930188046 923.0359777697051 2411.8425814744696 1193.3440363595637 2635.309411506137 1954.6087305406993 1482.246146092353 0.3739137479676372 1.434152148524035 1.2741578936242612 0.6161709345148801 0.6227278648712333 1.6271538892732578 0.805091677590512 1.7779161837955229 1.3186802581296206 1.0 10.533569330321711 -6.759617926020058 24.999983316611193 1.3230958507442174 0.904880510172934 0.2375033363170691 0.3915910365795162 79.71262726868653 1094084.1222898893 0.1331895269632555 0.12676078254334963 1.7393303453747858e-07 6.759617926020058 -0.4182153405712834 AWS(ph)QCGGGGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AWSQCGGGGLR 11 0 D6RER6;P36551-2;P36551 D6RER6 CPOX Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial 1 AWS(1)QCGGGGLR 80.438 0.016168000000000002 3948200.0 16308.0 14331.0 12702.0 16438.0 18268.0 18372.0 16452.0 17164.0 16453.0 14874.0 True False 19068.622302317985 15753.686969720507 13004.863852603261 15517.032152715054 14688.516537935258 17408.53997794242 14893.547457834753 16713.46318676125 16693.59399898206 17570.538457480794 1.0852611232411815 0.8965967097618032 0.740151696777758 0.8831278671547232 0.8359741833456167 0.9907801072841109 0.8476432007975093 0.9512208875787391 0.9500900635105257 1.0 14.100870783646677 -8.274119937621988 1.0198106266157316 0.9989936053965786 0.8894242205137743 0.11517910297420475 0.0877949036691235 1.0655968449745112 2.29348382564411 0.08466753556343608 0.029026331661183045 5.319613290379315e-09 8.274119937621988 -0.10956938488280421 AWSS(ph)QDEVSTNVR ddPTM_PC-9_Lapatinib_30min_R1 1 AWSSQDEVSTNVR 13 0 A1L390-3;A1L390;A0A0U1RR71 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 AWS(0.044)S(0.956)QDEVSTNVR 119.65 0.00022469 3395300.0 10009.0 9931.3 13059.0 12272.0 11147.0 11173.0 10039.0 10083.0 10948.0 15401.0 True False 9866.269824574198 9908.30468502725 11985.33942919777 13174.523818191905 10491.355375845205 10695.156835535114 10558.770298795755 10551.492989801214 9714.920952449078 18063.042329457454 0.5462130711216987 0.54854019075561 0.663528281149622 0.7293635024431467 0.5808188446049181 0.5921016316334102 0.5845510466183412 0.5841481627152972 0.5378341463888314 1.0 14.140753283662306 -11.784330192959702 2.433921075840626 2.7335099217786625 0.5995396544420429 0.8250857750551138 0.055739005959212516 9663506.450588878 1788304.2067844376 92050499.74613301 0.01533686998330955 1.64312198683666e-12 11.784330192959702 -2.1339702673366197 AWSTGDCDNGGDEWEQEIR ddPTM_PC-9_AZD4547_30min_R2 1 AWSTGDCDNGGDEWEQEIR 19 0 Q9BRF8-3;Q9BRF8-2;Q9BRF8 Q9BRF8-3 CPPED1 Serine/threonine-protein phosphatase CPPED1 0 147.35 5.265e-14 0.0 2771.9 1447.3 5523.7 4608.2 5161.3 3972.0 2348.1 4749.8 3509.3 3748.4 False True 3653.306540898302 1915.1114215059295 5450.452128878535 3545.8506859802806 4444.742585523013 3723.6302120944124 2557.07635112756 4015.8275495457315 3694.7944336220553 3617.1696569241653 1.0099903757361675 0.5294502617094358 1.5068278919251161 0.9802832109886351 1.2287901887639323 1.02943200492862 0.7069274028196819 1.1102126608461496 1.0214600873225 1.0 11.820645551293586 -5.232297407808828 24.99888524652739 1.0645517699562448 0.7697204402566049 0.2330603645058198 0.21963164136768926 1052.0462802360794 902474.7283745531 0.05454634497400028 0.1442659579871274 5.857369105271718e-06 5.232297407808828 -0.2948313296996399 AWSTGDCDNGGDEWEQEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AWSTGDCDNGGDEWEQEIR 19 0 Q9BRF8-3;Q9BRF8-2;Q9BRF8 Q9BRF8-3 CPPED1 Serine/threonine-protein phosphatase CPPED1 0 133.47 2.1949e-06 0.0 1501.8 908.06 2973.8 3166.0 2480.9 2372.7 1488.0 1003.3 2784.4 1575.4 False True 1756.0250780979381 998.2061956405279 3044.7066701993044 2988.6192843104886 1994.7854542896646 2248.271435100367 1347.0458678129164 976.9644380842205 2825.116582432726 1861.0075491404623 0.9435883690579266 0.5363794446194301 1.6360528314920342 1.6059146485949682 1.0718846654926197 1.2080936674000968 0.7238261168983824 0.5249653278061381 1.5180575617425913 1.0 10.861868192335034 -7.239861299564717 23.898318494552292 0.9021260140834859 1.1752715073879751 0.07429148424000631 0.3787335866491001 1156.0722960523237 1280382.9540474543 0.15247858701600842 0.11797239505953092 5.7562374468335855e-08 7.239861299564717 0.27314549330448923 AWYDNHR ddPTM_PC-9_AZD4547_30min_R2 1 AWYDNHR 7 0 Q5F1R6;Q5F1R6-3;Q5F1R6-2 Q5F1R6 DNAJC21 DnaJ homolog subfamily C member 21 0 114.78 0.00051208 0.0 5193.1 3722.9 5729.4 7597.8 6586.9 6305.4 5300.0 7051.9 6589.3 7302.8 False True 6844.397776809756 4926.254619722538 5653.42441247654 5846.244594839844 5672.422633170236 5911.122341223595 5771.68973253953 5962.190891541017 6937.596945677434 7047.131194799327 0.9712317803677069 0.6990439774071522 0.8022306178503784 0.8295921323494418 0.8049264979423677 0.8387983958047938 0.8190126695525333 0.8460451106602103 0.9844569022352346 1.0 12.782820357300762 -8.23963470504563 3.071284202749044 1.0023917184338977 0.8184313929861077 0.5347791725934721 0.062134359100275115 0.18221537247656605 3.253934280745935 0.05224649994404978 0.015360295633815704 5.759241565557647e-09 8.23963470504563 -0.18396032544779006 AWYDNHR ddPTM_PC-9_Lapatinib_30min_R1 1 AWYDNHR 7 0 Q5F1R6;Q5F1R6-3;Q5F1R6-2 Q5F1R6 DNAJC21 DnaJ homolog subfamily C member 21 0 130.77 3.4109e-06 0.0 8803.3 6061.2 7407.2 8276.6 6695.3 5020.7 5232.3 5762.7 7790.1 4991.9 False True 8677.763327672492 6047.165663799018 6798.208608618864 8885.288773928225 6301.495617466257 4805.976364823335 5503.202892159476 6030.45607977065 6912.696904610298 5854.743263711355 1.4821765766329449 1.0328660696841019 1.1611454682830005 1.517622272013306 1.0763060536785523 0.8208688491281169 0.9399563130751123 1.0300120446183167 1.1807002618639677 1.0 12.51539019316973 -6.508753535620302 24.592655353932138 0.9878753019979544 1.273085713662153 0.457942063816256 0.1558988699650796 528.2449782253618 919701.2162799964 0.05025658025998161 0.054779337791139304 3.099177599671192e-07 6.508753535620302 0.2852104116641986 AYDAS(ph)LAMLMRK ddPTM_PC-9_Lapatinib_30min_R1 1 AYDASLAMLMRK 12 1 Q9NR50-3;Q9NR50-2;Q9NR50 Q9NR50-3 EIF2B3 Translation initiation factor eIF-2B subunit gamma 1 AY(0.019)DAS(0.981)LAMLMRK 57.858999999999995 0.042982 20130000.0 14377.0 16982.0 13931.0 14925.0 17048.0 19243.0 11818.0 6268.2 10978.0 11554.0 True False 14171.981343581107 16942.679222370978 12785.646955215107 16022.63428834046 16045.270157657578 18420.021747623934 12429.878214081898 6559.443455189128 9741.542036535073 13551.093505262732 1.0458182830837413 1.2502813308602057 0.9435140382028686 1.1823868149177683 1.1840572239743017 1.3593015014227667 0.9172601612744097 0.48405270413355855 0.7188749773405243 1.0 13.726121654078119 -7.517510021084099 8.115060274976097 0.7001178443800061 1.1558833305725702 0.6003319909968738 0.15684468504292193 0.07439252088213558 45.053833332153616 0.068075936454465 0.04194096980381328 3.0373160068965126e-08 7.517510021084099 0.4557654861925641 AYDATHLVK ddPTM_PC-9_AZD4547_30min_R2 1 AYDATHLVK 9 0 H7BZT7;X6RA14;U3KQT1;P10768 H7BZT7 ESD S-formylglutathione hydrolase 0 73.985 0.02465 0.0 39691.0 42580.0 43721.0 66833.0 61832.0 48846.0 42975.0 50018.0 40459.0 46331.0 False True 52311.9123759134 56343.15230271714 43141.230973206075 51425.684409556874 53247.69409800999 45791.651898278855 46799.69174639362 42288.86739929643 42597.58014131446 44708.96579205889 1.1700541815083751 1.260220434638743 0.9649346659874815 1.15023202837519 1.190984697469064 1.024216308452661 1.0467630131293728 0.9458699536012907 0.9527748939538331 1.0 15.448276553389638 -7.141537584065301 1.5432950033352602 0.9671722353600826 1.1434174037006863 0.5023104205197169 0.07565016135527343 0.34757830146984964 1.6385043560303234 0.041686440110699725 0.027625370469126286 7.218756887447498e-08 7.141537584065301 0.17624516834060378 AYDATHLVK ddPTM_PC-9_Lapatinib_30min_R1 2 AYDATHLVK 9 0 H7BZT7;X6RA14;U3KQT1;P10768 H7BZT7 ESD S-formylglutathione hydrolase 0 ; 91.584 0.0064527000000000004 7518900.0 132981.0 131192.0 107550.0 120943.0 124713.0 116501.0 104692.0 115839.0 123573.0 102827.0 False True 131084.66655427136 130888.2329844123 98707.65415500599 129837.55167402107 117377.62653519178 111518.52380709526 110112.43949810971 121221.30283106052 109654.90745862167 120600.50994163477 1.086932937660964 1.085304142144642 0.8184679667007716 1.0765920619809703 0.973276369992111 0.9246936340573122 0.9130346094838172 1.0051475146309596 0.9092408275196326 1.0 16.879876481912888 -5.080852255758788 24.99975540719082 0.9552622547264337 1.0865311742674604 0.3980054186836367 0.06563829721509372 82.31114882521936 25449.924099145486 0.015874515333198145 0.0420000525160194 8.301331255324922e-06 5.080852255758788 0.1312689195410267 AYDSHSLK ddPTM_PC-9_Lapatinib_30min_R1 2 AYDSHSLK 8 0 Q9NVP1 Q9NVP1 DDX18 ATP-dependent RNA helicase DDX18 0 ; 91.853 0.007061199999999999 4057600.0 90735.0 75978.0 90040.0 84256.0 89291.0 84108.0 84934.0 73677.0 93499.0 68792.0 False True 89441.102261239 75802.07760907443 82637.25876445111 90452.46730977636 84039.07893286039 80510.89690532425 89331.46693474638 77100.30239111226 82968.15803188128 80682.60554042185 1.108554956327348 0.9395095398982587 1.024226451425766 1.1210900627702192 1.041600954381139 0.9978718010660727 1.1071961092033828 0.9556000562287882 1.0283276980973846 1.0 16.299970054223536 -7.780323679046106 24.999998913314855 0.9939729379231551 1.0440172682324085 0.16471298948846724 0.05498613186676457 503.9213026419933 667108.0552648575 0.029767816455266587 0.014340760916010565 1.658350480538513e-08 7.780323679046106 0.05004433030925337 AYGELPEHAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AYGELPEHAK 10 0 X6RAC9;A6NJH9;P47813;O14602 X6RAC9 EIF1AX;EIF1AY Eukaryotic translation initiation factor 1A, X-chromosomal;Eukaryotic translation initiation factor 1A, Y-chromosomal 0 82.831 0.014297 0.0 26015.0 24472.0 25744.0 27743.0 26724.0 27219.0 27493.0 26108.0 24709.0 21321.0 False True 30418.825680328824 26901.41843018633 26357.83459466368 26188.649654019566 21487.624039839156 25791.587723689023 24888.664007917017 25422.692663712587 25070.322380164573 25186.32852305685 1.2077514851949096 1.0680960667037833 1.0465135706672917 1.0397962382665318 0.8531463416816901 1.0240312596604975 0.9881815043082863 1.0093846207254604 0.9953940828340232 1.0 14.62035321152134 -4.333759192622902 0.9332196944461317 0.9843007316290572 1.5319673787078354 0.6553964563968878 0.04859999639178401 2.685778148682683 1.0421304713472088 0.016585281528963963 1.8183381214224936 4.637039627978281e-05 4.333759192622902 0.5476666470787782 AYGPGIEPTGNMVK ddPTM_PC-9_Lapatinib_30min_R1 2 AYGPGIEPTGNMVK 14 0 Q60FE5;P21333-2;P21333;A0A087WWY3;F8WE98 Q60FE5 FLNA Filamin-A 0 ; 199.19 3.0123e-07 10594900.0 29958.0 33297.0 32964.0 36000.0 41015.0 33195.0 31364.0 29442.0 32325.0 30553.0 False True 29530.79342637565 33219.902842261574 30253.827164719754 38647.56009247951 38602.578338592546 31775.32723132445 32987.874454769386 30809.98280330529 28684.218102659503 35834.04534068651 0.8240987905668006 0.9270486356320814 0.8442760753659343 1.0785151306542131 1.0772598508369524 0.8867356986693954 0.9205735534780511 0.8597963894498726 0.8004739021215395 1.0 15.129043299556596 -10.092432443034236 10.485261626446604 0.9999999999913946 0.9191335121885594 0.07164707923224989 0.0915188569943284 0.0 0.0 0.09513671856785083 0.023074043673674435 8.08290653521649e-11 10.092432443034236 -0.08086648780283512 AYGPGLEK ddPTM_PC-9_Lapatinib_30min_R1 2 AYGPGLEK 8 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 98.523 0.02525 13064700.0 79144.0 80584.0 70839.0 81674.0 87703.0 73937.0 71996.0 72774.0 77266.0 62846.0 False True 78015.39204676807 80397.4126990661 65014.890866447684 87680.57841647712 82544.4819707323 70774.88686556515 75723.6006008664 76155.34571454873 68563.48943294941 73708.84736296893 1.0584264282765428 1.0907430461252539 0.8820500278113281 1.1895529716359063 1.1198721038772121 0.9601952736697142 1.0273339403610005 1.033191379856103 0.930193482680825 1.0 16.169550177711145 -8.129333620878334 5.42531531854261 0.9660446556866322 1.0460875140366919 0.13713072088769673 0.08080178619075491 0.46551347914689384 18.123988122330072 0.057578273302107956 0.02096402996556487 7.424485768603374e-09 8.129333620878334 0.08004285835005964 AYGVPVKPMT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 AYGVPVKPMTPK 12 1 H3BT74;F8W872;Q15131-4;Q15131-3;Q15131-2;Q15131 H3BT74 CDK10 Cyclin-dependent kinase 10 1 AYGVPVKPMT(1)PK 76.868 0.011764 17395000.0 151840.0 156720.0 149570.0 178480.0 178400.0 189580.0 160120.0 154780.0 155700.0 162540.0 True False 200121.9615318003 207376.6751733638 147586.60407269807 137334.19348851204 153632.239408154 177725.53263062902 174370.36980645862 130862.3074905654 163929.98413215 156849.52407332545 1.2758850415015952 1.3221377393304519 0.9409439075103788 0.8755792808418711 0.9794880814323199 1.1330957724012236 1.1117048064802695 0.8343175298982016 1.0451417376026881 1.0 17.259021626072297 -5.258625035590393 24.98804532221519 0.9891070973681261 1.2990114215309805 0.6581025406632367 0.08907959087917207 148.0510931249899 1314501.8544006187 0.024579204492039906 0.05927860760796601 5.5128346221889565e-06 5.258625035590393 0.3099043241628544 AYHLQK ddPTM_PC-9_AZD4547_30min_R2 2 AYHLQK 6 0 P61927;D6R9X9;D6RG19 P61927 RPL37 60S ribosomal protein L37;Ribosomal protein L37 0 ; 118.18 0.017159 20356000.0 221662.0 205147.0 263240.0 338930.0 309070.0 263471.0 239433.0 272570.0 242952.0 250495.0 False True 292145.9051439797 271456.75588176405 259749.26560203946 260794.92491630063 266160.96543653647 246996.1167197201 260742.07315681851 230450.5695354923 255793.94672366176 241725.24629474393 1.2085866479488705 1.1229971219090928 1.0745640746408351 1.078889892197294 1.101088816813107 1.021805212760231 1.0786712482604597 0.9533574712113272 1.058201204237324 1.0 17.883008633523467 -1.5228787452803376 0.29943337882548404 1.0068726667983952 2.6084509698007965 0.7078525327060649 0.035903483153756945 29.137056241840703 0.4151474230599784 0.035713716822813 24.979469125746785 0.029999999999999995 1.5228787452803376 1.6015783030024013 AYHLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AYHLQK 6 0 P61927;D6R9X9;D6RG19 P61927 RPL37 60S ribosomal protein L37;Ribosomal protein L37 0 123.53 0.012294 5681600.0 112100.0 102120.0 112190.0 115780.0 131830.0 113820.0 123080.0 115670.0 111830.0 98294.0 False True 131076.31592407677 112257.79871243177 114865.0350829445 109293.22196382453 105998.85784957328 107851.07883134148 111420.97137796649 112633.78506249575 113465.30218842544 116113.92410512429 1.128859582812878 0.9667901552513086 0.9892442785668918 0.9412585338591727 0.9128867073134719 0.9288384632810962 0.95958320448365 0.9700282367558453 0.9771894547780428 1.0 16.82518146156619 -4.1565250382506616 1.589887176674891 0.9541964804050104 1.8028847381336857 0.7829472759392255 0.02631419986583909 3.100906967208997 1.7937462059831415 0.00762635201579372 6.68945665458994 6.973887893741497e-05 4.1565250382506616 0.8486882577286753 AYHLQK ddPTM_PC-9_Lapatinib_30min_R1 1 AYHLQK 6 0 P61927;D6R9X9;D6RG19 P61927 RPL37 60S ribosomal protein L37;Ribosomal protein L37 0 100.36 0.029586 9726300.0 134770.0 129880.0 136020.0 133950.0 144980.0 138280.0 136470.0 117780.0 137390.0 105840.0 False True 132848.15508620918 129579.27083980358 124836.96065238399 143801.12984410056 136452.56144164703 132366.08674642383 143535.74884716162 123252.48877702959 121915.69141916138 124134.30297706502 1.07019697134606 1.0438635230726236 1.0056604633728745 1.1584318467609165 1.0992333156038097 1.0663135295558046 1.156293992915731 0.9928962891087538 0.9821273289921034 1.0 16.921542315904034 -7.8507095189182845 11.14446980883551 0.990128302510696 1.0835700161766262 0.4882646253623091 0.0440756591750768 0.40381907258223 47.71536697965805 0.02510095594620505 0.012052356283305695 1.4102317269827162e-08 7.8507095189182845 0.09344171366593024 AYILVT(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 1 AYILVTPLK 9 0 Q6P0N0 Q6P0N0 MIS18BP1 Mis18-binding protein 1 1 AYILVT(1)PLK 103.31 0.0070819 36613000.0 70348.0 65223.0 96781.0 138860.0 127000.0 105390.0 96737.0 109090.0 85420.0 114110.0 True False 92717.20067070013 86305.0592447186 95497.62070441786 106847.97236561391 109368.24217957171 98799.9466396351 105346.40559559914 92232.6471388152 89935.12681161384 110115.04363238074 0.8420030325759726 0.7837717390627224 0.8672531704499599 0.9703303821258614 0.993217988858069 0.8972429504680477 0.956694036713987 0.8376026026628483 0.8167378756336183 1.0 16.748652054067847 -5.522318975950404 6.170306769648738 0.9209228522427076 0.8152473937958028 0.36435916514330846 0.059398163723493075 0.1660594449791646 27.33661719240283 0.016974805876308594 0.03201097365933841 3.0038692425735186e-06 5.522318975950404 -0.10567545844690485 AYILVT(ph)PLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AYILVTPLK 9 0 Q6P0N0 Q6P0N0 MIS18BP1 Mis18-binding protein 1 1 AY(0.006)ILVT(0.994)PLK;AYILVT(1)PLK 108.47 0.00595 51950000.0 146413.0 146884.0 161586.0 193491.0 190491.0 165088.0 175716.0 183718.0 156915.0 128205.0 True False 171197.82911143478 161465.6727974617 165438.82305831762 182650.32657628626 153165.65600108515 156430.4946591854 159070.9084063269 178895.5971653117 159209.58502098493 151447.55162977814 1.130410015012572 1.0661491127448095 1.092383609229563 1.2060302369415983 1.0113445503266174 1.0329021035717258 1.0503366128703386 1.1812379615263229 1.051252287063587 1.0 17.20845872949232 -6.290520275973089 24.995259772397358 1.0622848701825827 1.1173894597586218 0.24947507674243918 0.05747136863881098 1325.6651466918388 1139415.4970574216 0.01861702525214544 0.0211122540458534 5.122473543354594e-07 6.290520275973089 0.05510458957603914 AYILVT(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 2 AYILVTPLK 9 0 Q6P0N0 Q6P0N0 MIS18BP1 Mis18-binding protein 1 1 AYILVT(1)PLK;AYILVT(1)PLK 121.9 0.003885 56157000.0 194218.0 167086.0 188365.0 162817.0 158370.0 158790.0 148776.0 128272.0 161417.0 129160.0 True False 191448.41570478043 166699.12263273337 172878.35680992727 174791.10532159018 149054.9879673998 151998.92185756916 156478.89331344122 134231.98539995824 143236.5176636348 151485.13390511795 1.2638099249045343 1.1004322228552448 1.1412232497890444 1.153849891508627 0.9839578586025459 1.0033916724315206 1.0329653430642975 0.8861066557463906 0.9455483450498209 1.0 17.208816695239335 -6.115540624520276 0.6813457771794802 0.9451971018853703 1.216052593681292 0.7456197852771538 0.05395653497669377 0.45538506223993824 0.4301471235265775 0.03289391506459466 0.07382398599386411 7.664068460287705e-07 6.115540624520276 0.2708554917959217 AYIQENLELVEK ddPTM_PC-9_Lapatinib_30min_R1 1 AYIQENLELVEK 12 0 V9GZ78;V9GYY3;A0A384N5Y3;F5H2F4;P11586;A0A494C1T2 V9GZ78 MTHFD1 C-1-tetrahydrofolate synthase, cytoplasmic;Methylenetetrahydrofolate dehydrogenase;Methenyltetrahydrofolate cyclohydrolase;Formyltetrahydrofolate synthetase;C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed 0 115.14 0.003394 1459700.0 12735.0 11061.0 14868.0 10359.0 12948.0 11619.0 13615.0 10975.0 12203.0 11039.0 False True 12553.396564687017 11035.388934085813 13645.610432139716 11120.835416610977 12186.424096747432 11122.08245521189 14319.918081293365 11484.938566207313 10828.569636713197 12947.076441457095 0.9695931449427843 0.8523460090766147 1.0539530289977963 0.8589456829807217 0.9412491037533368 0.85904200114232 1.106034875598662 0.887068105153998 0.8363718006668789 1.0 13.660338741586108 AYLGYQAVPSGSSGSLST(ph)SSSSSPPGTPSPADAK ddPTM_PC-9_AZD4547_30min_R2 1 AYLGYQAVPSGSSGSLSTSSSSSPPGTPSPADAK 34 0 P17676-3;P17676-2;P17676 P17676-3 CEBPB CCAAT/enhancer-binding protein beta 1 AYLGYQAVPSGS(0.001)S(0.008)GS(0.019)LS(0.114)T(0.281)S(0.281)S(0.114)S(0.114)S(0.033)S(0.033)PPGTPSPADAK 85.274 3.327e-11 11595000.0 73442.0 79682.0 113160.0 158280.0 140430.0 123770.0 116980.0 137150.0 105410.0 130710.0 True False 96795.02831150207 105437.64823356298 111659.42446256938 121790.99140162296 120933.71849824589 116030.64233407006 127390.99337971226 115956.61889346848 110981.75740121987 126133.88268502738 0.7673991020573891 0.8359185176028746 0.88524528132855 0.9655691936935836 0.9587726622214034 0.9199006632009702 1.0099664790136054 0.9193137991559901 0.8798726800344019 1.0 16.94459634578545 -5.1853260938469505 1.4974030060473567 0.9489387302569734 0.7588784581001699 0.7201074155016229 0.0377491236505681 0.31631801561402273 1.0770953564535914 0.011282060595798922 0.07112970813881458 6.526403278721157e-06 5.1853260938469505 -0.19006027215680354 AYLGYQAVPSGSSGSLST(ph)SSSSSPPGTPSPADAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AYLGYQAVPSGSSGSLSTSSSSSPPGTPSPADAK 34 0 P17676-3;P17676-2;P17676 P17676-3 CEBPB CCAAT/enhancer-binding protein beta 1 AYLGYQAVPSGS(0.001)S(0.004)GS(0.003)LS(0.072)T(0.203)S(0.203)S(0.203)S(0.203)S(0.053)S(0.053)PPGTPSPADAK 82.226 2.3773e-08 6828500.0 43280.0 43159.0 43914.0 54629.0 59231.0 54139.0 49211.0 50406.0 52460.0 42717.0 True False 50606.44918103525 47443.54029210574 44961.07630477243 51568.31423960762 47625.110743291174 51299.85553373748 44549.37782321333 49082.89590957167 53227.12825543056 50461.25395241405 1.0028773606925845 0.9401974104100925 0.8910019625586714 1.021938818409815 0.9437956256141115 1.0166187225968313 0.8828432576254301 0.9726848238027894 1.054811842480664 1.0 15.622888437002219 -8.10865448098701 6.038709861150107 1.0256861248751035 0.9561420605511013 0.26058887149678156 0.04661866916858915 0.3065106940594654 14.388742342932774 0.03125633661319795 0.011551336316846668 7.786557930475895e-09 8.10865448098701 -0.06954406432400217 AYLGYQAVPSGSSGSLSTS(ph)SSSSPPGTPSPADAK ddPTM_PC-9_AZD4547_30min_R2 1 AYLGYQAVPSGSSGSLSTSSSSSPPGTPSPADAK 34 0 P17676-3;P17676-2;P17676 P17676-3 CEBPB CCAAT/enhancer-binding protein beta 1 AYLGYQAVPSGSSGSLS(0.007)T(0.02)S(0.283)S(0.283)S(0.283)S(0.062)S(0.062)PPGTPSPADAK 127.42 5.735e-24 10878000.0 142530.0 137880.0 203780.0 277960.0 231440.0 209760.0 177620.0 226340.0 189860.0 210420.0 True False 187851.57519183037 182447.01360964382 201077.7440525131 213880.61643919084 199308.5509451968 196643.6740405149 193427.83590446622 191364.35377577602 199895.611993128 203053.2598468634 0.9251344959125617 0.8985180230410476 0.9902709476526494 1.053322742025876 0.9815579966335397 0.9684339674665533 0.9525965554571427 0.9424342850742569 0.9844491644403207 1.0 17.631498663123097 -5.264290630850871 24.989965342215648 0.9827693772346044 0.9118262561584918 0.4975604011373653 0.02903838199426709 212.85696405182608 1865614.4519050808 0.00847830975075101 0.01893549485342746 5.441383923295345e-06 5.264290630850871 -0.07094312107611267 AYLGYQAVPSGSSGSLSTS(ph)SSSSPPGTPSPADAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AYLGYQAVPSGSSGSLSTSSSSSPPGTPSPADAK 34 0 P17676-3;P17676-2;P17676 P17676-3 CEBPB CCAAT/enhancer-binding protein beta 1 AYLGYQAVPSGSS(0.003)GS(0.009)LS(0.081)T(0.081)S(0.231)S(0.231)S(0.231)S(0.064)S(0.064)PPGT(0.007)PS(0.001)PADAK;AYLGYQAVPSGSSGSLS(0.007)T(0.021)S(0.282)S(0.282)S(0.282)S(0.062)S(0.062)PPGTPSPADAK 124.98 3.6689999999999995e-15 0.0 44923.1 46972.7 50589.3 62354.0 69368.0 64611.0 63372.0 51658.0 52102.0 47741.4 True False 52527.69355833095 51635.83922424046 51795.54077298865 58860.507534395576 55775.8383623545 61222.68541883506 57368.9453864517 50302.03223617529 52863.89318270002 56396.53789928557 0.9313992580916278 0.9155852672455375 0.9184170288163167 1.0436900867835226 0.9889940134616148 1.0855752444975995 1.0172423259190604 0.891934755392361 0.9373606102755059 1.0 15.783318979960061 -5.73594923717076 24.91872789621351 0.9949223932537682 0.9211789267433806 0.30833448207494285 0.0502180476763144 302.15854769770823 295382.5521965038 0.015190758932576607 0.026298919403472204 1.836753021026553e-06 5.73594923717076 -0.07374346651038755 AYLGYQAVPSGSSGSLSTS(ph)SSSSPPGTPSPADAK ddPTM_PC-9_Lapatinib_30min_R1 1 AYLGYQAVPSGSSGSLSTSSSSSPPGTPSPADAK 34 0 P17676-3;P17676-2;P17676 P17676-3 CEBPB CCAAT/enhancer-binding protein beta 1 AYLGYQAVPSGSSGSLS(0.002)T(0.01)S(0.234)S(0.234)S(0.234)S(0.144)S(0.144)PPGTPSPADAK 131.83 3.3209e-22 7410200.0 145830.0 124110.0 151120.0 124400.0 140590.0 143160.0 120670.0 122570.0 145130.0 95183.0 True False 143750.43745805338 123822.63092029566 138695.4969400692 133548.79098623473 132320.7726105748 137037.38052225948 126917.70215715544 128265.0496637841 128783.93111334811 111635.25472662454 1.2876795758658264 1.109171392348375 1.242398714274541 1.1962958414281641 1.1852955675570904 1.2275457323749595 1.1368962472290225 1.1489654408715513 1.153613447908707 1.0 16.768433180701322 -10.270787201242022 0.2701846416519595 0.8994084128068508 1.2199281016077619 0.642847260477754 0.045403275075739706 7.482276041858595 0.5572756390064363 0.6638708682187263 0.06238378436506384 5.360592553725522e-11 10.270787201242022 0.3205196888009111 AYPGYYFT(ph)GDGAY(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AYPGYYFTGDGAYR 14 0 Q9NUB1-3;Q9NUB1-4;Q9NUB1-2;Q9NUB1 Q9NUB1-3 ACSS1 Acetyl-coenzyme A synthetase 2-like, mitochondrial 2 AYPGY(0.001)Y(0.001)FT(0.999)GDGAY(1)R 67.997 0.031093 13228000.0 19123.0 25299.0 30372.0 29631.0 32218.0 35052.0 27708.0 28286.0 29516.0 21392.0 True False 22360.14620353366 27810.517524733717 31096.18366645143 27970.871134998142 25905.114178848147 33213.81141448061 25083.297651451823 27543.52247149434 29947.61566121403 25270.200261021182 0.8848424615781052 1.1005262023044164 1.2305475756128739 1.1068717638198813 1.0251250053924705 1.314346980689041 0.9926038334623865 1.0899605933863419 1.1850960954752572 1.0 14.625149476932151 -4.76868833371232 5.035883958169936 1.1228103630900457 0.8713382984306525 0.33622315266323777 0.09753547625997165 0.18063569344997116 12.19288884773532 0.023313116646724433 0.15911789388254477 1.7033804806890423e-05 4.76868833371232 -0.2514720646593932 AYPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AYPSPR 6 0 Q7Z7M8 Q7Z7M8 B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 1 AYPS(1)PR 115.46 0.023393999999999998 12542000.0 85419.0 76129.0 84247.0 95401.0 103670.0 88248.0 71494.0 74701.0 65494.0 55502.0 True False 99878.74959784756 83686.58400096673 86255.7679885269 90055.99126421506 83356.6077013218 83620.11952827474 64721.57074826396 72740.1779022519 66451.7258475252 65564.07324640971 1.5233762127998496 1.2764091652214333 1.315595015952586 1.3735569924973587 1.271376282374073 1.2753954320989929 0.9871499365974508 1.1094517820586316 1.013538704311116 1.0 16.000617865924756 -7.07863620900455 2.0155386978897116 1.0315513708613044 1.3522830908775336 0.8056820210236556 0.07517398052158028 0.1447559958503124 1.1650845592715637 0.03351887832409229 0.024577132678516193 8.343798183376993e-08 7.07863620900455 0.3207317200162292 AYQDQIS(ph)PVPGAPK ddPTM_PC-9_AZD4547_30min_R2 2 AYQDQISPVPGAPK 14 0 W0Z7M9;A0A499FIJ6;Q969V6;E7ER32;A0A087X287;A0A087WU73;A0A494BZX7;B0QY83 W0Z7M9 mkl1;MKL1 MKL/myocardin-like protein 1 1 AYQDQIS(1)PVPGAPK;AYQDQIS(1)PVPGAPK 110.57 0.00048198 57067000.0 427470.0 397090.0 545980.0 691450.0 627920.0 544900.0 443060.0 577540.0 511310.0 554230.0 True False 563396.5680716457 525441.5769818211 538739.948463005 532046.8852960084 540744.1466881613 510827.31686058664 482491.48167905 488294.4635489169 538336.8027399465 534826.5763944836 1.0534191697610948 0.9824522568120471 1.0073170860260972 0.9948026309440074 1.0110644656695462 0.9551270251084245 0.9021456729614131 0.9129958852096293 1.0065632982734833 1.0 19.028711631490893 -6.8061359371430585 5.291555251124704 0.9458159324197537 1.0074298384494238 0.3572431684979598 0.035434656458962446 0.19586144144003723 12.486545579230803 0.012412600222383753 0.011151759500135363 1.5626584433035057e-07 6.8061359371430585 0.061613906029670096 AYQDQIS(ph)PVPGAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AYQDQISPVPGAPK 14 0 W0Z7M9;A0A499FIJ6;Q969V6;E7ER32;A0A087X287;A0A087WU73;A0A494BZX7;B0QY83 W0Z7M9 mkl1;MKL1 MKL/myocardin-like protein 1 1 AYQDQIS(1)PVPGAPK;AYQDQIS(1)PVPGAPK 158.91 0.0001633 25978000.0 72234.0 75695.0 85507.0 103415.0 121331.0 133780.0 155374.0 143579.0 124445.0 117811.0 True False 84461.78951346806 83209.49934917249 87545.81116710343 97620.9928259535 97557.06153187114 126764.34129376957 140655.84990965363 139810.20338452532 126264.77269819003 139169.20170863732 0.6069000071603203 0.5979016788741717 0.6290602381293248 0.701455434301703 0.700996056125372 0.9108649021294353 1.0106823074557023 1.0046059161654888 0.9072752530587636 1.0 17.086480451008953 -6.7206859640987044 1.7867038147713765 0.9852569948184116 0.6261834649253827 0.9490271492188628 0.037537064431848954 0.07370079745079289 0.48601862991909994 0.016185443500960503 0.015244771288597364 1.9024534360768634e-07 6.7206859640987044 -0.3590735298930289 AYQDQIS(ph)PVPGAPK ddPTM_PC-9_Lapatinib_30min_R1 1 AYQDQISPVPGAPK 14 0 W0Z7M9;A0A499FIJ6;Q969V6;E7ER32;A0A087X287;A0A087WU73;A0A494BZX7;B0QY83 W0Z7M9 mkl1;MKL1 MKL/myocardin-like protein 1 1 AYQDQIS(1)PVPGAPK 106.42 0.00087728 19214000.0 93341.0 103720.0 127560.0 128450.0 170250.0 193350.0 193370.0 185490.0 197010.0 167220.0 True False 92009.94022335683 103479.84271253782 117072.50919583964 137896.64149663894 160236.2297243783 185080.87122086392 203381.75243332316 194108.54256453732 174820.65919272846 196123.75419335606 0.4691422546023942 0.527625239166686 0.5969318182662323 0.7031103502163654 0.8170159213167179 0.9436943116966592 1.0370072369347545 0.9897247957693489 0.8913793227737976 1.0 17.581404757450322 -6.107847596679682 0.9958052372098101 0.9871433207152929 0.4812221916474658 0.9603688471012621 0.03959933710810737 0.10542919236558972 0.21637995330111875 0.018528543364513473 0.034704487247507326 7.801038177859774e-07 6.107847596679682 -0.505921129067827 down AYQDTTLNS(ph)SSEYCVEK ddPTM_PC-9_AZD4547_30min_R2 2 AYQDTTLNSSSEYCVEK 17 0 X6R717;Q7L7V1-2;Q7L7V1 X6R717 DHX32 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 1 AYQDTTLNS(0.374)S(0.374)S(0.249)EY(0.002)CVEK;AYQDTT(0.002)LNS(0.348)S(0.348)S(0.302)EYCVEK 291.68 7.183299999999999e-98 8759100.0 34355.0 41096.0 40243.0 52382.0 48411.0 47761.0 32576.0 50432.0 37740.0 41803.0 True False 45279.17537160834 54379.47832391883 39709.351525690916 40306.13919383251 41689.96828468695 44774.49711979891 35475.20089192599 42638.893212070005 39734.859352262974 40339.48969384295 1.1224528548887256 1.3480457669800125 0.9843791239568355 0.9991732542909304 1.0334778303120211 1.1099420805670943 0.8794162038529852 1.0570013040739583 0.9850114528922198 1.0 15.299905213108188 -5.275845536779705 24.998917825096463 1.0080076493505896 1.2352493119220185 0.5972833150378505 0.07526678707683611 435.61478982599476 755919.5474057955 0.018583808649233965 0.038972136647448315 5.2985185999050805e-06 5.275845536779705 0.22724166257142886 AYQDTTLNS(ph)SSEYCVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AYQDTTLNSSSEYCVEK 17 0 X6R717;Q7L7V1-2;Q7L7V1 X6R717 DHX32 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 1 AYQDTTLNS(0.48)S(0.48)S(0.041)EYCVEK 270.95 7.849499999999998e-173 0.0 13540.0 12640.0 13327.0 13798.0 13454.0 12033.0 14555.0 13303.0 10851.0 9808.1 True False 15832.054572810002 13894.815665150181 13644.766222928949 13024.94279371957 10817.785280347114 11401.968297114148 13176.24503092541 12953.810345693597 11009.67534692484 11586.230889123126 1.3664542614693407 1.1992524400833664 1.1776708364873278 1.1241742822462715 0.9336759627760043 0.9840964163607374 1.1372330792488308 1.1180348872431258 0.9502378687499191 1.0 13.500123699824913 -5.006201131862998 0.9068284770097614 1.0323056027269901 1.455126863715315 0.7042926616731795 0.06936150125323697 1.0050696651521096 0.8211076222212768 0.027030671944208808 0.39240687036721256 9.858228224444972e-06 5.006201131862998 0.42282126098832484 AYQDTTLNS(ph)SSEYCVEK ddPTM_PC-9_Lapatinib_30min_R1 2 AYQDTTLNSSSEYCVEK 17 0 X6R717;Q7L7V1-2;Q7L7V1 X6R717 DHX32 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 1 AYQDTTLNS(0.494)S(0.494)S(0.012)EYCVEK;AYQDTTLNS(0.44)S(0.44)S(0.121)EYCVEK 297.73 3.650799999999999e-112 8924300.0 36709.0 37904.0 47962.0 43078.0 50066.0 42482.0 43805.0 43719.0 48385.0 32516.0 True False 36185.522928393875 37816.2356168148 44018.74949867398 46246.09982399533 47121.21631354321 40665.14389037881 46073.00856048886 45750.34434405623 42935.37178336211 38136.34727515347 0.9488460619292033 0.991606126931112 1.1542466083885543 1.2126515287457935 1.2355985740732844 1.0663093556648224 1.2081127809140302 1.1996519754230217 1.1258385988984134 1.0 15.218879047521442 -5.221217460317422 3.7951811701750824 1.1626661800690916 0.9594106158437201 0.5143326847919597 0.06968893554073814 0.15859106377417476 4.882026096818088 0.017473003816336544 0.050203451062007985 6.008727925882635e-06 5.221217460317422 -0.2032555642253715 AYQHGGVTGLS(ph)QY ddPTM_PC-9_AZD4547_30min_R2 2 AYQHGGVTGLSQY 13 0 Q92900-2;Q92900 Q92900-2 UPF1 Regulator of nonsense transcripts 1 1 AYQHGGVTGLS(1)QY;AYQHGGVTGLS(1)QY 127.78 0.00011298 38137000.0 137818.0 121322.0 153680.0 250880.0 199818.0 210831.0 147194.0 185948.0 136539.0 179830.0 True False 181641.25720751882 160536.9639189819 151642.10278727172 193043.49205736123 172076.71980974523 197647.70424120827 160293.98084743827 157214.00925995412 143756.17279010697 173534.2064359921 1.0467173068527962 0.9251027057780438 0.8738456002517564 1.1124232854262375 0.9916011565893527 1.1389553005165607 0.9237025030368439 0.9059540046241105 0.8284025135017474 1.0 17.40486054410755 -7.49758010610977 24.66346473313033 0.9032725671567673 1.0096486160950904 0.25560554869961993 0.08339186488531838 880.3120023284355 858213.1179113776 0.03585771608585575 0.024051052801641166 3.1799470893843856e-08 7.49758010610977 0.10637604893832309 AYQHGGVTGLS(ph)QY ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AYQHGGVTGLSQY 13 0 Q92900-2;Q92900 Q92900-2 UPF1 Regulator of nonsense transcripts 1 1 AYQHGGVT(0.001)GLS(0.944)QY(0.055);AYQHGGVTGLS(0.986)QY(0.014);AYQHGGVTGLS(1)QY 103.14 0.0015742 20255600.0 97697.0 92047.0 101634.0 101896.0 119620.0 101179.0 112146.0 104542.0 99309.0 85981.0 True False 114235.17249629376 101184.8178425695 104057.34000909155 96187.09747128907 96181.31969935475 95872.9951245501 101522.71901327124 101797.8832714052 100761.20625083007 101568.67467477873 1.1247087043527244 0.9962207163435151 1.0245022920923355 0.9470153842144601 0.9469584988415551 0.9439228721998578 0.9995475409947542 1.0022566859059685 0.9920500250049127 1.0 16.632095996037812 -3.1811637199173157 1.1938060210242314 0.9772426554820981 7.031736047863287 0.7238398683153282 0.026248527731500774 35.26241076827681 1.5737539837887293 0.008410291186778144 545.3713070523925 0.000658925447334185 3.1811637199173157 6.054493392381189 AYQHGGVTGLS(ph)QY ddPTM_PC-9_Lapatinib_30min_R1 2 AYQHGGVTGLSQY 13 0 Q92900-2;Q92900 Q92900-2 UPF1 Regulator of nonsense transcripts 1 1 AYQHGGVTGLS(0.908)QY(0.091);AYQHGGVT(0.001)GLS(0.984)QY(0.015) 80.37100000000001 0.012831 35493000.0 131211.0 85799.0 119611.0 112408.0 111307.0 106103.0 84439.0 82495.0 141985.0 86452.0 True False 129339.90707884982 85600.33768697479 109777.04529181188 120674.85930209549 104760.14109798179 101565.22202817349 88810.83825679982 86328.01886280367 125993.15413166612 101395.11300995082 1.275602967828997 0.8442254774012043 1.082666038165355 1.1901447290684766 1.0331872808081068 1.0016776845862974 0.8758887447374708 0.8514021662398219 1.2425959239209219 1.0 16.629628594172416 -6.660479415732574 3.5389470463563537 0.9769222835945648 1.0816161270413607 0.09354765506463347 0.1427676746423141 0.5834661309582144 14.206032864275796 0.04933309979872425 0.04862461360609434 2.1853478961925967e-07 6.660479415732574 0.10469384344679589 AYQQKPYPS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 AYQQKPYPSPK 11 1 A0A2R8YDI1;A0A2R8Y852;P39880-6;P39880-4;P39880-5;P39880-2;P39880;P39880-3 A0A2R8YDI1 CUX1 Homeobox protein cut-like 1 1 AYQQKPY(0.002)PS(0.998)PK 72.321 0.012987 61587000.0 234990.0 245470.0 202410.0 280210.0 253390.0 303300.0 261090.0 185000.0 288930.0 270910.0 True False 309711.93190435896 324813.37707252166 199725.91114765525 215611.91370134443 218211.1723297767 284334.6030534334 284326.50420165074 156412.50087708136 304202.2499377145 261425.52335858677 1.1847042627109508 1.2424700270255875 0.7639878026511563 0.8247546411357789 0.8346972764035181 1.0876313812076535 1.0876004016319847 0.5983061595043139 1.163628730774128 1.0 17.996040474886485 -5.246864854622475 24.647327207684686 0.9112431802297268 1.2135872098159874 0.33827676840313703 0.16383303826504267 721.6498483007779 1220393.0273128839 0.04097767708507026 0.10733885467124823 5.664155209120613e-06 5.246864854622475 0.3023440295862606 AYQQKPYPS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AYQQKPYPSPK 11 1 A0A2R8YDI1;A0A2R8Y852;P39880-6;P39880-4;P39880-5;P39880-2;P39880;P39880-3 A0A2R8YDI1 CUX1 Homeobox protein cut-like 1 1 AYQQKPYPS(1)PK 118.76 0.0032240000000000003 0.0 8136.1 10062.0 8978.2 12777.0 11522.0 10336.0 11970.0 10419.0 9099.4 9970.2 True False 9513.381034700118 11060.888862558631 9192.274338013109 12061.146113592898 9264.346811369063 9793.961964511906 10836.114944704717 10145.51228984302 9232.461510626476 11777.718335940228 0.8077439758148754 0.9391368130112129 0.780480062081505 1.0240647440844104 0.7865994539110771 0.8315670051834402 0.9200521387608527 0.8614157683567233 0.7838921977318146 1.0 13.523772456557069 -10.597190793167153 4.6446443241385555 1.000006865203189 0.8631815430038037 0.2335099145055889 0.07612748814086327 5.074255406910268e-06 1.0113473837229172e-06 0.06911158328704846 0.01676118016061779 2.5281870756085404e-11 10.597190793167153 -0.13682532219938537 AYRPPS(ph)GEK ddPTM_PC-9_AZD4547_30min_R2 1 AYRPPSGEK 9 1 P30414;A0A087WYW3 P30414 NKTR NK-tumor recognition protein;Putative peptidyl-prolyl cis-trans isomerase 1 AYRPPS(1)GEK 97.734 0.022628 13323000.0 28183.0 28275.0 34334.0 33376.0 32002.0 36129.0 25215.0 37707.0 32269.0 32109.0 True False 37144.60775718347 37414.34080223877 33878.708726562945 25681.67885405969 27559.074694729516 33869.84791862012 27459.086152072487 31880.249570659988 33974.67346153085 30984.873683218964 1.1987981018396259 1.2075034155295565 1.0933950892596747 0.828845685046913 0.8894364061795476 1.0931091172065557 0.8862093947132661 1.0288971934045983 1.0964922371115273 1.0 14.91927646640133 -5.532404891094491 7.412934048493417 0.9724128526313761 1.1909039418541056 0.5510739643652162 0.08319306314996103 0.0983918836802334 32.96989633179189 0.023421320267751584 0.042488215341821234 2.934912168629527e-06 5.532404891094491 0.21849108922272953 AYRPPS(ph)GEK ddPTM_PC-9_Lapatinib_30min_R1 1 AYRPPSGEK 9 1 P30414;A0A087WYW3 P30414 NKTR NK-tumor recognition protein;Putative peptidyl-prolyl cis-trans isomerase 1 AYRPPS(1)GEK 97.45200000000001 0.023066 15242000.0 44792.0 51337.0 43551.0 40854.0 37837.0 43811.0 41944.0 39793.0 50902.0 34854.0 True False 44153.25786615319 51218.13233063586 39970.40489172158 43858.53944494884 35611.50205040415 41937.30565842914 44115.65508643182 41641.928051488634 45168.8807381771 40878.46745996428 1.0801104006503224 1.2529367051442934 0.9777862864078247 1.0729007756443705 0.8711555071207473 1.0259021011367873 1.079190533002197 1.0186763506306118 1.1049553357746293 1.0 15.319053489979726 -5.2725204575336795 24.993757690091496 1.0185544954376704 1.1665235570972596 0.3979076024581869 0.07267503622267485 614.8945583088654 1386917.527364547 0.018699366244517103 0.03951254115279106 5.339241223727807e-06 5.2725204575336795 0.14796906165958923 AYS(ph)FCGTVEYMAPEVVNR ddPTM_PC-9_AZD4547_30min_R2 7 AYSFCGTVEYMAPEVVNR 18 0 B4DG22;B1AXG1;B7ZB17;P51812;Q9UK32-2;Q9UK32;E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2 B4DG22;E9PGT3 RPS6KA3;RPS6KA6;RPS6KA1 Ribosomal protein S6 kinase alpha-3;Ribosomal protein S6 kinase alpha-6;Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 AYS(0.869)FCGT(0.13)VEY(0.001)MAPEVVNR;AYS(0.822)FCGT(0.172)VEY(0.005)MAPEVVNR;AYS(0.644)FCGT(0.049)VEY(0.307)MAPEVVNR;AYS(0.999)FCGTVEYMAPEVVNR;AYS(1)FCGTVEYMAPEVVNR;AYS(0.991)FCGT(0.009)VEYMAPEVVNR;AYS(0.97)FCGT(0.029)VEYMAPEVVNR 230.97 1.6682e-35 149418800.0 103623.5 104877.20000000001 132101.5 202987.8 153230.69999999998 148405.9 129608.1 157613.2 131108.5 137990.89999999997 True False 136573.61749730344 138776.70391457327 130349.74779641315 156192.09884024734 131957.262259412 139126.05561255343 141142.96981584097 133257.70153102442 138038.6276466925 133159.88059216095 1.0256363770376005 1.042181048056174 0.9788965506483548 1.1729666484053778 0.9909686136139436 1.0448045987564796 1.0599511593745752 1.0007346126958696 1.036638265465813 1.0 17.022799956327006 -8.133096666405752 1.004615770979347 1.0048489714544708 1.0452852466769182 0.06101167852166256 0.0507046481020417 1.5654431158401938 3.08219996955268 0.046079643603618804 0.016380626847070517 7.360432488221323e-09 8.133096666405752 0.040436275222447415 AYS(ph)FCGTVEYMAPEVVNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AYSFCGTVEYMAPEVVNR 18 0 B4DG22;B1AXG1;B7ZB17;P51812;Q9UK32-2;Q9UK32;E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2 B4DG22;E9PGT3 RPS6KA3;RPS6KA6;RPS6KA1 Ribosomal protein S6 kinase alpha-3;Ribosomal protein S6 kinase alpha-6;Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 AYS(0.99)FCGT(0.008)VEY(0.002)MAPEVVNR;AYS(0.912)FCGT(0.053)VEY(0.034)MAPEVVNR 84.195 0.0017347999999999999 73967000.0 88557.0 99125.0 106623.0 110769.0 120443.0 106952.0 111834.0 107671.0 107069.0 85597.0 True False 103547.95101952263 108965.47490569689 109165.29668997944 104562.9720479434 96843.0587573098 101343.24884176446 101240.27391195559 104844.75033685443 108634.68157035256 101115.05851452095 1.0240606348920058 1.0776384497670894 1.0796146320214255 1.0340989125069566 0.9577511023583332 1.002256739308624 1.0012383456952325 1.0368856219550906 1.0743669950480397 1.0 16.62563834038655 -5.99587692307108 18.746180861130167 1.0113512619323577 1.0612748822132807 0.32427432108752496 0.031303049063628456 6.50629514949853 29563.4367007885 0.009422264542389492 0.01382308020171599 1.009538943932882e-06 5.99587692307108 0.04992362028092301 AYS(ph)FCGTVEYMAPEVVNR ddPTM_PC-9_Lapatinib_30min_R1 6 AYSFCGTVEYMAPEVVNR 18 0 B4DG22;B1AXG1;B7ZB17;P51812;Q9UK32-2;Q9UK32;E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2 B4DG22;E9PGT3 RPS6KA3;RPS6KA6;RPS6KA1 Ribosomal protein S6 kinase alpha-3;Ribosomal protein S6 kinase alpha-6;Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 AYS(0.995)FCGT(0.004)VEY(0.001)MAPEVVNR;AYS(0.971)FCGT(0.024)VEY(0.005)MAPEVVNR;AYS(0.902)FCGT(0.038)VEY(0.06)MAPEVVNR;AYS(1)FCGTVEYMAPEVVNR;AYS(0.687)FCGT(0.313)VEYMAPEVVNR;AYS(0.996)FCGT(0.004)VEYMAPEVVNR 254.68 3.935999999999999e-65 95906200.0 86927.1 114958.2 137377.5 116576.2 137747.6 142013.69999999998 133163.30000000002 131191.0 140971.0 104220.1 True False 85687.5036135221 114692.02135091077 126082.85224248547 125149.60263480291 129645.55699020134 135940.1051011038 140057.84410096915 137286.61279629168 125093.36148955955 122234.40542044597 0.7010096978734048 0.9382957356106745 1.0314841538174306 1.0238492362631424 1.0606306509551338 1.1121263660056655 1.1458135998552652 1.1231421490870028 1.0233891273024132 1.0 16.89929089333473 -4.231951638027471 0.9457100878534948 1.084548790651693 1.1355289504270822e-11 0.8649017732033797 0.04432561762173525 1.7118180331902473 0.5881968141129755 0.015081291586115918 2.439880554589466 5.8620343906244036e-05 4.231951638027471 -1.0845487906403377 AYS(ph)GSDLPSSSSGGANGTAGGGGGAR ddPTM_PC-9_AZD4547_30min_R2 3 AYSGSDLPSSSSGGANGTAGGGGGAR 26 0 Q8NHG8 Q8NHG8 ZNRF2 E3 ubiquitin-protein ligase ZNRF2 1 AYS(0.987)GS(0.013)DLPSSSSGGANGTAGGGGGAR;AYS(0.899)GS(0.101)DLPSSSSGGANGTAGGGGGAR;AYS(0.499)GS(0.499)DLPS(0.002)SSSGGANGTAGGGGGAR 299.9 1.3227999999999998e-153 44214400.0 53530.0 51700.0 72853.0 111911.0 91065.0 72732.0 76334.0 86932.0 70320.0 72923.0 True False 70551.42650683141 68411.0139513968 71886.92161869544 86111.6479577143 78422.19664632024 68184.05654230902 83127.57812144773 73498.65689862912 74036.9716388748 70369.9879660338 1.0025783511698934 0.9721617969356118 1.0215565427323057 1.2236984891809088 1.1144267451654686 0.9689365951749218 1.1812930558062873 1.0444602738045865 1.052110051157192 1.0 16.102672645850006 -5.5359075681892715 24.952822865463908 1.088813361243819 0.9897423000184421 0.22675787261870062 0.07310879351639626 289.88811304750703 555191.87036976 0.019775874836191212 0.034276308766944555 2.911336678059798e-06 5.5359075681892715 -0.09907106122537679 AYS(ph)GSDLPSSSSGGANGTAGGGGGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AYSGSDLPSSSSGGANGTAGGGGGAR 26 0 Q8NHG8 Q8NHG8 ZNRF2 E3 ubiquitin-protein ligase ZNRF2 1 AYS(0.938)GS(0.062)DLPSSSSGGANGTAGGGGGAR;AYS(0.938)GS(0.061)DLPSSSSGGANGTAGGGGGAR 279.86 2.0467999999999995e-121 25069400.0 21405.1 23951.9 25090.9 30879.1 46469.0 51069.0 55683.0 55384.0 51734.0 46434.0 True False 25028.560660004096 26329.686339407483 25689.16221376814 29149.04413839294 37363.73303050763 48390.85173816359 50408.30312999103 53930.22868419866 52490.51187888763 54852.11662865824 0.45629161094081794 0.480012221181109 0.4683349302212066 0.5314114737946798 0.6811721283875933 0.8822057326568348 0.918985560233687 0.983193211107957 0.9569459686349322 1.0 15.743259671841562 -6.594549553363546 1.3029617384026904 0.9740992421934254 0.4618672947723454 0.9939722229371806 0.01726918655816212 0.02819869260924918 0.10000461100201473 0.007422371827432295 0.007794239107979509 2.543609548595059e-07 6.594549553363546 -0.5122319474210799 down AYS(ph)GSDLPSSSSGGANGTAGGGGGAR ddPTM_PC-9_Lapatinib_30min_R1 3 AYSGSDLPSSSSGGANGTAGGGGGAR 26 0 Q8NHG8 Q8NHG8 ZNRF2 E3 ubiquitin-protein ligase ZNRF2 1 AYS(0.773)GS(0.227)DLPSSSSGGANGTAGGGGGAR;AYS(0.828)GS(0.026)DLPS(0.146)SSSGGANGTAGGGGGAR;AYS(0.905)GS(0.095)DLPSSSSGGANGTAGGGGGAR 323.87 2.613299999999999e-213 34353400.0 28561.3 26289.899999999998 27434.0 26903.2 43130.0 48318.0 40777.0 41278.0 59645.0 45670.0 True False 28154.010624499057 26229.02735179664 25178.482418302443 28881.751074444303 40593.17819684253 46251.551774759275 42888.23353660666 43195.92657274762 52927.152010305545 53563.998648550165 0.5256144301180007 0.48967642471752976 0.47006353247647165 0.53920080283674 0.7578444332206569 0.8634820577572989 0.8006914087577652 0.8064358088007835 0.9881105471153644 1.0 15.708976044003709 -6.371867120242621 1.9401045872568654 0.8781526615448411 0.4900066140134668 0.892207657356316 0.06333268344710682 0.10630602483131532 0.789709735791337 0.022671891771883283 0.027352009610592566 4.2474950337613915e-07 6.371867120242621 -0.38814604753137427 AYS(ph)PEYR ddPTM_PC-9_AZD4547_30min_R2 3 AYSPEYR 7 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 AYS(0.998)PEY(0.002)R;AYS(1)PEYR;AYS(0.997)PEY(0.003)R 83.78299999999999 0.020513 954191000.0 218494.0 209168.0 294893.0 393918.0 324411.0 295554.0 235437.0 365104.0 289182.0 285867.0 True False 287970.5470424745 276777.46549682366 290982.5261403369 303106.2910724315 279372.13239147293 277072.961657944 256390.43689809626 308685.5660552748 304467.57014324615 275858.8833411432 1.0439052879306892 1.003329898767641 1.0548238382466404 1.0987729936454231 1.0127356748775969 1.004401084721638 0.9294260666640518 1.118998099015489 1.1037076872624174 1.0 18.073570914019143 -10.694422193266812 5.032635491852191 0.9999973456245408 1.039199692627477 0.04789626701824656 0.054398970760451235 1.7091482250736946e-06 2.8135630388068653e-07 0.055565662555417554 0.013475740193748259 2.0210534846784065e-11 10.694422193266812 0.03920234700293612 AYS(ph)PEYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 AYSPEYR 7 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 AYS(1)PEYR;AYS(1)PEYR;AYS(1)PEYR;AYS(1)PEYR;AYS(0.996)PEY(0.004)R;AYS(1)PEYR 100.25 0.011581999999999999 1628730900.0 407953.0 422206.0 500273.0 486562.0 552241.0 485462.0 479205.0 436759.0 437963.0 352381.0 True False 477011.38546097185 464119.82141775184 512201.40561591875 459301.5085952883 444033.3403451884 460003.518112992 433811.23325624346 425294.53903441195 444367.38033040747 416264.8858535395 1.1459323177905658 1.1149627008919745 1.2304698835350094 1.103387588538734 1.066708616160862 1.105074037580104 1.0421518797261164 1.0216920847463686 1.0675110859260795 1.0 18.667142339084577 -6.592171826609385 0.8679292871122356 1.0307757227835934 1.159564006447539 0.6446026045236662 0.03770067912552224 0.39383920171347175 0.6528839206061182 0.022609646587235434 0.025402966898375155 2.557573794424301e-07 6.592171826609385 0.12878828366394557 AYS(ph)PEYR ddPTM_PC-9_Lapatinib_30min_R1 5 AYSPEYR 7 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 AYS(1)PEYR;AYS(0.986)PEY(0.014)R;AYS(0.988)PEY(0.012)R;AYS(0.979)PEY(0.021)R;AYS(0.999)PEY(0.001)R 93.598 0.013808 1458674000.0 492006.0 558572.0 640408.0 592857.0 577457.0 575694.0 498524.0 527851.0 583799.0 458046.0 True False 484989.9042171507 557278.6608525625 587756.1262863697 636457.6814929747 543492.1145841434 551072.9096282598 524335.1334233336 552376.8844748142 518045.4089439914 537218.6407920688 0.9027793665202818 1.0373405137820935 1.0940724719078792 1.1847274706525244 1.0116776919408923 1.025788883304132 0.9760181304398897 1.0282161535951102 0.9643101888277581 1.0 19.03514983972282 -6.495245582420317 24.77615977952412 1.0013722356067336 1.0615360960241276 0.13117347422495584 0.06734904120337168 1336.0221262834664 1197892.2301591313 0.022119228280683974 0.025012788686713226 3.197086727679282e-07 6.495245582420317 0.060163860417393966 AYS(ph)PEYRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AYSPEYRR 8 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 AYS(0.999)PEY(0.001)RR 54.25899999999999 0.043126 22071000.0 15245.0 2103.4 8384.7 32278.0 30268.0 54490.0 20548.0 52245.0 39112.0 26228.0 True False 17825.677397525018 2312.2116511136787 8584.623047151821 30469.56830668795 24337.20268065602 51632.44847583727 18601.544685362784 50873.624108153235 39683.9390073656 30982.928779266236 0.5753386816501981 0.07462856941597497 0.2770759055191918 0.9834308603865163 0.7855036189136021 1.66648055913906 0.6003804487912366 1.6419888665334261 1.2808323993541268 1.0 14.919185906362825 -5.969139272314244 1.6714770580423632 1.2144950858988641 0.26468851811257654 0.5577778311355028 0.33753377070936125 0.25555633420692464 1.4445594554860552 0.10806118959397083 0.18660132829264478 1.0736450538101652e-06 5.969139272314244 -0.9498065677862876 AYS(ph)PTCSPTLGFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AYSPTCSPTLGFK 13 0 Q5TGY3 Q5TGY3 AHDC1 AT-hook DNA-binding motif-containing protein 1 1 AYS(0.91)PT(0.027)CS(0.013)PT(0.05)LGFK 100.73 0.0072683999999999995 0.0 12829.0 12773.0 11674.0 12831.0 17993.0 13915.0 15803.0 11964.0 13567.0 11780.0 True False 15000.696315700117 14041.019026183807 11952.35243389154 12112.120668663267 14467.400813831237 13185.2729040425 14306.025436187852 11649.957676905828 13765.391708757654 13915.620749571315 1.0779753620521908 1.0090113318600145 0.8589162243631672 0.8703974394413122 1.039651846956013 0.947515970816371 1.0280551398778646 0.8371856266106359 0.9892042875041497 1.0 13.764417645556621 -5.005894486037122 6.291537556089053 0.9433452876470969 1.0633417276857575 0.2728271553584558 0.06763046272692129 0.16368694677496462 31.50680120807702 0.017067450228367295 0.056982501226859925 9.865191361542937e-06 5.005894486037122 0.11999644003866061 AYS(ph)QEEITQGFEETGDTLYAPYSTHFQLQNQPPQK ddPTM_PC-9_AZD4547_30min_R2 2 AYSQEEITQGFEETGDTLYAPYSTHFQLQNQPPQK 35 0 Q8NFJ5 Q8NFJ5 GPRC5A Retinoic acid-induced protein 3 1 AY(0.08)S(0.861)QEEIT(0.059)QGFEETGDTLYAPYSTHFQLQNQPPQK;AY(0.004)S(0.996)QEEIT(0.001)QGFEETGDTLYAPYSTHFQLQNQPPQK 104.39 4.4899e-21 8179500.0 17161.0 21821.0 61828.0 76712.0 73448.0 49555.0 52415.0 83424.0 53746.0 54919.0 True False 22617.841029025476 28874.211517087624 61008.120322302435 59027.23358858541 63251.01300476518 46456.318016198034 57079.833458690446 70532.73769280873 56586.90383536631 52996.30252604259 0.4267814913674587 0.544834453363963 1.1511769201695308 1.1137990911645053 1.19349860254276 0.8765954566994408 1.0770531289544434 1.3308992199625373 1.0677519211375035 1.0 15.693604088028646 -5.214849658903316 4.734483521834893 1.1088809358088452 0.46297423905099633 0.8227713632983109 0.11448297796625308 0.07895831018677912 4.063697411439711 0.03048199610855295 0.08388986249393299 6.097479390853584e-06 5.214849658903316 -0.6459066967578488 down AYS(ph)QEEITQGFEETGDTLYAPYSTHFQLQNQPPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AYSQEEITQGFEETGDTLYAPYSTHFQLQNQPPQK 35 0 Q8NFJ5 Q8NFJ5 GPRC5A Retinoic acid-induced protein 3 1 AY(0.001)S(0.989)QEEIT(0.01)QGFEETGDTLYAPYSTHFQLQNQPPQK 97.613 5.0499e-16 4962300.0 4062.1 4735.7 7853.3 10218.0 18624.0 12173.0 13023.0 9411.3 10979.0 8755.3 True False 4749.733299867913 5205.828998849026 8040.5524558061 9645.518587202967 14974.760893502633 11534.626450658227 11789.367161644905 9164.263347096614 11139.547104772631 10342.566583083337 0.459241259092955 0.503340148408023 0.7774233205283404 0.9326039634088036 1.4478766728943158 1.1152576449954563 1.1398879636828256 0.8860724534358815 1.0770582925705177 1.0 13.336306624893824 -5.577281517843987 1.9574571782920722 1.1080210799704628 0.47076922483396494 0.757620158899716 0.1394071527451498 0.1706895342978791 1.2963486142980807 0.044214867847679494 0.10866658968868066 2.646783887362199e-06 5.577281517843987 -0.6372518551364978 down AYS(ph)SFGGGR ddPTM_PC-9_AZD4547_30min_R2 1 AYSSFGGGR 9 0 Q15056;Q15056-2 Q15056;Q15056-2 EIF4H Eukaryotic translation initiation factor 4H 1 AYS(0.5)S(0.5)FGGGR 74.165 0.027826 9387200.0 64715.0 59625.0 95423.0 112240.0 102130.0 84785.0 75103.0 104390.0 75730.0 85435.0 True False 85293.02384437891 78897.61521957509 94157.62867171936 86364.80209071371 87951.01239212339 79483.38054693474 81787.02150621069 88258.92414355952 79732.93319414086 82443.94665438993 1.0345577486960018 0.9569849385100245 1.1420805588848615 1.047557832872318 1.0667976966316206 0.9640899516872226 0.9920318571000353 1.0705324978381534 0.9671168888649423 1.0 16.331125948987882 -6.744309159777149 24.986084647595483 1.002742360826677 1.0494755383984968 0.20249224870531946 0.050137215135671695 456.6835586010509 666115.0373633798 0.016878285326550432 0.016837372089245562 1.8017346893157818e-07 6.744309159777149 0.04673317757181983 AYS(ph)SPSTTPEAR ddPTM_PC-9_Lapatinib_30min_R1 1 AYSSPSTTPEAR 12 0 G3V2R1;Q9UPU9-2;Q9UPU9-3;Q9UPU9 G3V2R1 SAMD4A Protein Smaug homolog 1 1 AYS(0.577)S(0.363)PS(0.021)T(0.03)T(0.009)PEAR 128.36 0.00020698 22565000.0 29076.0 26802.0 29044.0 24208.0 31516.0 25762.0 21965.0 25139.0 28530.0 24135.0 True False 28661.37090811462 26739.941615709977 26656.114433082173 25988.337075520678 29662.290842839997 24660.21931415515 23102.240224429577 26307.049714431487 25316.650965781148 28306.702592133995 1.012529481836545 0.9446505303355468 0.9416891404543002 0.9180983546540826 1.0478893027647345 0.8711795107144642 0.8161402815900337 0.9293576187055365 0.8943694831066711 1.0 14.788856081069959 -6.800511798630236 24.999980897250804 0.8924148735997366 0.9666118014770174 0.2738624227290394 0.05602088072073056 204.12819045579286 130607.35163019347 0.01938713837116951 0.017098148991072815 1.5830265594854884e-07 6.800511798630236 0.07419692787728083 AYS(ph)TENYSLESQK ddPTM_PC-9_AZD4547_30min_R2 2 AYSTENYSLESQK 13 0 Q6ZV73-2;Q6ZV73;F8VY01 Q6ZV73-2 FGD6 FYVE, RhoGEF and PH domain-containing protein 6 1 AYS(0.5)T(0.5)ENYSLESQK;AYS(0.818)T(0.182)ENYSLESQK 233.28 8.7626e-26 21003200.0 52620.0 54542.0 66081.0 79890.0 82317.0 84764.0 62193.0 69610.0 69772.0 65045.0 True False 69352.0654360072 72171.63487305783 65204.72276344167 61472.594788195995 70888.70544484865 79463.69368025464 67728.05651619451 58853.373978668256 73460.00547763894 62767.79434815711 1.1048988761868672 1.1498195152874098 1.0388245029252985 0.9793652210753659 1.12938022087644 1.2659946793651786 1.0790255929740669 0.9376364836435617 1.1703454970900338 1.0 15.937736893251644 -10.719653934329008 4.219783518169603 0.9999622572871479 1.092526999544939 0.09081909994749471 0.08989066484872303 3.3462109281665564e-05 6.369209900934123e-06 0.09124593930360286 0.022121370439593932 1.9069796811667952e-11 10.719653934329008 0.09256474225779099 AYS(ph)TENYSLESQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AYSTENYSLESQK 13 0 Q6ZV73-2;Q6ZV73;F8VY01 Q6ZV73-2 FGD6 FYVE, RhoGEF and PH domain-containing protein 6 1 AYS(0.946)T(0.054)ENYSLESQK;AYS(0.982)T(0.018)ENYSLESQK;AYS(0.939)T(0.06)ENYS(0.001)LESQK 121.92 0.00018977 14921300.0 57841.0 58312.7 54521.0 69931.0 68514.0 69496.0 56888.0 60690.0 55697.0 53506.0 True False 67632.33888817612 64101.59948079137 55820.987412043905 66012.99278936085 55089.173531864275 65851.50741928401 51499.156806546496 59096.95180637034 56511.46325662825 63206.21424673706 1.070026732247574 1.014166094975393 0.8831566338419896 1.0444066865271668 0.8715784387404311 1.0418517894810242 0.814779961437179 0.934986417248066 0.8940808104093275 1.0 15.947778786404628 -1.5228797541045151 0.6312438085600324 0.925950479999769 12.545815855375364 0.25555687934129234 0.07226594140575383 257.36964936454643 1.7820606637305878 0.029300757689516795 4160.4129541131115 0.029999930312975556 1.5228797541045151 11.619865375375596 AYSFCGT(ph)VEYMAPEVVNR ddPTM_PC-9_Lapatinib_30min_R1 1 AYSFCGTVEYMAPEVVNR 18 0 B4DG22;B1AXG1;B7ZB17;P51812;Q9UK32-2;Q9UK32;E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2 B4DG22;E9PGT3 RPS6KA3;RPS6KA6;RPS6KA1 Ribosomal protein S6 kinase alpha-3;Ribosomal protein S6 kinase alpha-6;Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 AY(0.004)S(0.451)FCGT(0.515)VEY(0.03)MAPEVVNR 105.36 0.00084186 7678300.0 3904.2 4365.5 5092.1 4901.7 6087.8 6231.3 5562.0 3931.6 4931.8 3801.4 True False 3848.525392057406 4355.3919529655195 4673.447194074429 5262.187369591857 5729.727573075308 5964.80182486977 5849.973144924987 4114.2764890114495 4376.3287498436575 4458.4669249528915 0.8631947835069046 0.9768810728615058 1.0482184286079028 1.1802683429455871 1.285134031388121 1.3378593864824497 1.3121041926282313 0.922800720127563 0.9815770361220967 1.0 12.122331999294499 -5.276898324645986 1.8056691160820915 1.161736131997328 0.8777954775747492 0.30131935657033915 0.13754515955566135 0.5538849767069081 3.164506727416702 0.044349259520992 0.18864035028253037 5.2856898382864935e-06 5.276898324645986 -0.2839406544225789 AYSFCGTVEY(ph)MAPEVVNR ddPTM_PC-9_AZD4547_30min_R2 1 AYSFCGTVEYMAPEVVNR 18 0 B4DG22;B1AXG1;B7ZB17;P51812;Q9UK32-2;Q9UK32;E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2 B4DG22;E9PGT3 RPS6KA3;RPS6KA6;RPS6KA1 Ribosomal protein S6 kinase alpha-3;Ribosomal protein S6 kinase alpha-6;Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 AYS(0.397)FCGT(0.119)VEY(0.484)MAPEVVNR 166.11 1.3915999999999998e-07 55556000.0 13290.0 13901.0 16540.0 24414.0 17958.0 17623.0 13743.0 18532.0 16283.0 15831.0 True False 17515.943550827385 18394.226401128963 16320.668792955987 18785.729492539947 15464.84167764368 16521.031024103686 14966.100376281272 15668.305222994959 17143.68613759666 15276.761508581374 1.146574392811474 1.204065821856054 1.0683330222696885 1.229693183466109 1.0123115209304443 1.0814485134708276 0.9796644640864758 1.0256300207471096 1.1222068321199217 1.0 13.899051121176038 -6.275363227957631 24.997030634863393 1.0375263483825623 1.1584570092803037 0.5558953723858078 0.05481949256206216 597.3235538079571 1072352.6860305876 0.016298267462897958 0.01857442326518109 5.304406176016113e-07 6.275363227957631 0.1209306608977414 AYSFCGTVEY(ph)MAPEVVNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AYSFCGTVEYMAPEVVNR 18 0 B4DG22;B1AXG1;B7ZB17;P51812;Q9UK32-2;Q9UK32;E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2 B4DG22;E9PGT3 RPS6KA3;RPS6KA6;RPS6KA1 Ribosomal protein S6 kinase alpha-3;Ribosomal protein S6 kinase alpha-6;Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 AYSFCGT(0.002)VEY(0.998)MAPEVVNR 124.39 4.7113999999999996e-05 32321000.0 67273.0 74991.0 75190.0 87316.0 94845.0 74892.0 84777.0 81426.0 82969.0 65513.0 True False 78660.99019768438 82435.61088174672 76982.81475966302 82423.96760229128 76260.80310052916 70964.53168016893 76746.30882767186 79288.65377797853 84182.26466307328 77389.98829937734 1.0164233375173837 1.0651973555397214 0.9947386793994696 1.0650469061119427 0.9854091566149357 0.916973025059107 0.9916826519056258 1.0245337351810462 1.0877668612304285 1.0 16.23985932104736 -3.611173999362273 14.721586908422603 1.0135249065395955 1.0194017524639896 0.0 0.047001821451852006 0.0 0.0 0.011399581655019217 0.0 0.0002448082225262285 3.611173999362273 0.005876845924394081 AYSFCGTVEY(ph)MAPEVVNR ddPTM_PC-9_Lapatinib_30min_R1 1 AYSFCGTVEYMAPEVVNR 18 0 B4DG22;B1AXG1;B7ZB17;P51812;Q9UK32-2;Q9UK32;E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2 B4DG22;E9PGT3 RPS6KA3;RPS6KA6;RPS6KA1 Ribosomal protein S6 kinase alpha-3;Ribosomal protein S6 kinase alpha-6;Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 AYS(0.012)FCGT(0.181)VEY(0.807)MAPEVVNR 182.92 8.984199999999999e-10 33695000.0 15124.0 19190.0 21914.0 20123.0 24907.0 20814.0 23724.0 19765.0 21814.0 17667.0 True False 14908.328986598084 19145.566734030086 20112.315510486264 21602.912548360142 23442.019229046073 19923.833739803787 24952.312637576473 20683.354055679956 19357.077608396423 20720.717410202236 0.7194890356092443 0.9239818465263855 0.9706379905834528 1.0425755112959332 1.1313324131095939 0.961541694979823 1.2042204979491073 0.9981968117327886 0.9341895468766733 1.0 14.338786333646476 -4.496238941650127 1.1254050285488995 1.04506435790176 0.37637162136285823 0.6127912296704014 0.07636632294097742 1.8572442767705177 1.287410164881697 0.02348666674483043 1.7138437511850382 3.1897824066453906e-05 4.496238941650127 -0.6686927365389017 AYSGS(ph)DLPSSSSGGANGTAGGGGGAR ddPTM_PC-9_AZD4547_30min_R2 1 AYSGSDLPSSSSGGANGTAGGGGGAR 26 0 Q8NHG8 Q8NHG8 ZNRF2 E3 ubiquitin-protein ligase ZNRF2 1 AYS(0.124)GS(0.874)DLPS(0.001)SSSGGANGTAGGGGGAR 308.98 7.714999999999997e-173 30074000.0 22832.0 25459.0 35392.0 46494.0 37451.0 33666.0 26108.0 40690.0 31838.0 26950.0 True False 30092.101064897706 33688.123872120144 34922.678955278025 35775.52662513934 32251.575101316022 31560.859697978478 28431.56142210227 34402.29546318069 33520.89168143479 26006.48870294159 1.1570997303259163 1.2953737913995935 1.342844832079462 1.3756384813722575 1.2401357011209302 1.2135763523665781 1.093248755987823 1.3228350761281147 1.2889433888721489 1.0 14.666584004788996 -6.523058043176422 4.84714033638323 1.2001132307470899 1.2980778597753382 0.19525760646449442 0.10129815272401227 0.3515171458828821 23.088252221959088 0.033540826219115104 0.035391915021366814 2.998761709642658e-07 6.523058043176422 0.09796462902824832 AYSGS(ph)DLPSSSSGGANGTAGGGGGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AYSGSDLPSSSSGGANGTAGGGGGAR 26 0 Q8NHG8 Q8NHG8 ZNRF2 E3 ubiquitin-protein ligase ZNRF2 1 AYS(0.366)GS(0.634)DLPSSSSGGANGTAGGGGGAR 330.93 3.3901999999999985e-214 18973000.0 17542.0 15570.0 17238.0 22473.0 38739.0 40273.0 35877.0 41463.0 35663.0 31513.0 True False 20511.51412970702 17115.686701454768 17649.019295479055 21213.910668449033 31148.37104023834 38161.01298343541 32478.47083301345 40374.64018367992 36184.50390723255 37226.057443229234 0.550998830885802 0.459777045354767 0.47410390752215154 0.5698672415364112 0.8367356948218453 1.0251156207350727 0.872466037601323 1.0845800752672334 0.9720208475585931 1.0 15.18402521012808 -6.33638531575431 2.165546986475494 0.9903159291011603 0.4906350735868718 0.942729001346015 0.05573466990590665 0.06538312482303078 0.6019716444703935 0.018653940680201993 0.02278934549412289 4.6090846482780355e-07 6.33638531575431 -0.4996808555142885 AYSGS(ph)DLPSSSSGGANGTAGGGGGAR ddPTM_PC-9_Lapatinib_30min_R1 1 AYSGSDLPSSSSGGANGTAGGGGGAR 26 0 Q8NHG8 Q8NHG8 ZNRF2 E3 ubiquitin-protein ligase ZNRF2 1 AYS(0.337)GS(0.659)DLPS(0.004)SSSGGANGTAGGGGGAR 172.42 4.9135000000000003e-14 19254000.0 29236.0 27482.0 28175.0 27792.0 44234.0 50866.0 48910.0 49547.0 66573.0 45875.0 True False 28819.089278774238 27418.36711748904 25858.560258645182 29835.916391394167 41632.243087390045 48690.57975443738 51442.320481532006 51849.13450021625 59074.84769523123 53804.43262540487 0.5356266737244008 0.5095930907473764 0.48060278673834633 0.5545252488603797 0.7737697631204556 0.9049548035090165 0.9560981869222881 0.9636591628276852 1.097955034792762 1.0 15.715437412243293 -6.54284852191733 1.315833614985742 1.0081304989091038 0.49683743167722605 0.9701842967577955 0.038732160590552504 0.06777986872427408 0.24377850232619297 0.017430513966985525 0.019162937224904666 2.865177144147767e-07 6.54284852191733 -0.5112930672318777 AYSPTCS(ph)PTLGFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AYSPTCSPTLGFK 13 0 Q5TGY3 Q5TGY3 AHDC1 AT-hook DNA-binding motif-containing protein 1 1 AYS(0.375)PT(0.15)CS(0.468)PT(0.007)LGFK 105.66 0.0020525 0.0 12647.0 13792.0 13739.0 14462.0 21725.0 16648.0 18464.0 12160.0 13999.0 15377.0 True False 14787.887310363973 15161.178611847417 14066.589865447644 13651.74102643661 17468.142204217413 15774.949572870966 16714.95625221619 11840.812884584988 14203.708891493947 18164.728375734983 0.81409900574776 0.8346493434000476 0.7743903225240757 0.7515521699004889 0.9616517155055238 0.8684385060193711 0.9201875143117778 0.6518574150771403 0.7819389642218768 1.0 14.148852172282753 -4.7493538948066245 21.173613119807193 0.830064852627388 0.8140988011382729 0.0 0.09957238225537847 1321.062721169876 2313388.46112347 0.024985787096011226 0.33910094653496675 1.7809269468868275e-05 4.7493538948066245 -0.01596605148911512 AYSS(ph)PSTTPEAR ddPTM_PC-9_AZD4547_30min_R2 2 AYSSPSTTPEAR 12 0 G3V2R1;Q9UPU9-2;Q9UPU9-3;Q9UPU9 G3V2R1 SAMD4A Protein Smaug homolog 1 1 AYS(0.026)S(0.613)PS(0.1)T(0.1)T(0.16)PEAR;AYS(0.043)S(0.95)PS(0.004)T(0.002)T(0.001)PEAR 171.49 0.00031766 52686000.0 37096.0 36264.0 56033.0 71592.0 59195.0 56161.0 46391.0 57527.0 45370.0 51517.0 True False 48891.75635526652 47985.62881882892 55289.96580868816 55087.57048537391 50976.79603007671 52649.24379190193 50519.70912872478 48637.523988950525 47768.16557530926 49713.40551055438 0.9834722818352604 0.9652452558021066 1.1121741759765351 1.1081029335976302 1.0254134776434518 1.0590552638910296 1.0162190381022926 0.9783583218539426 0.9608709177078577 1.0 15.601347314954362 -7.599512305038612 3.1341650608814815 0.976808395010346 1.0440378422839203 0.27898459181164237 0.04475613376182517 0.3570106374634829 7.05373382849318 0.026317668693374194 0.014040516644820415 2.5147087617408193e-08 7.599512305038612 0.06722944727357427 AYSS(ph)PSTTPEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AYSSPSTTPEAR 12 0 G3V2R1;Q9UPU9-2;Q9UPU9-3;Q9UPU9 G3V2R1 SAMD4A Protein Smaug homolog 1 1 AYS(0.33)S(0.613)PS(0.024)T(0.017)T(0.017)PEAR;AYS(0.045)S(0.953)PS(0.001)T(0.002)TPEAR 155.47 0.00032067 29434200.0 43656.0 44823.0 48133.0 46551.0 56225.0 48525.0 56405.0 44195.0 45720.0 39199.0 True False 51046.09855469677 49272.731215112835 49280.67326541903 43942.8983903783 45208.11486453963 45980.26357661965 51061.91006316372 43034.928078473175 46388.56850625785 46305.46840088672 1.1023773285860827 1.0640801813845662 1.0642516956912011 0.9489785960039403 0.9763018586304577 0.9929769671812488 1.1027187895195962 0.929370322008212 1.0017946067330903 1.0 15.49889495681437 -5.62907149564192 6.638904489978694 0.9942404273410375 1.0785096021248748 0.4361997336997827 0.04386581024847788 0.20786886541969868 11.466953613175606 0.01219374590937724 0.021266738092736846 2.349246044854082e-06 5.62907149564192 0.08426917478383733 AYSS(ph)PSTTPEAR ddPTM_PC-9_Lapatinib_30min_R1 2 AYSSPSTTPEAR 12 0 G3V2R1;Q9UPU9-2;Q9UPU9-3;Q9UPU9 G3V2R1 SAMD4A Protein Smaug homolog 1 1 AYS(0.255)S(0.734)PS(0.005)T(0.005)TPEAR;AYS(0.309)S(0.689)PS(0.001)T(0.001)TPEAR 83.137 0.013822 20995000.0 46537.0 47706.0 48615.0 43161.0 47197.0 41550.0 41188.9 35476.0 50668.0 36180.0 True False 45873.373846159404 47595.5396880479 44618.062359326876 46335.20392087526 44420.96525287218 39773.00335778068 43321.45970316446 37124.344471505276 44961.23628230635 42433.664793180345 1.0810608527390702 1.1216457480169646 1.0514779380190982 1.0919444301290222 1.0468331092630778 0.9372983349807847 1.0209219475694873 0.8748795243693317 1.059565241452636 1.0 15.372921662246597 -6.578680267584285 4.5551850664071685 0.9737059468561224 1.0850970609228274 0.5204108492108979 0.04900785588550141 0.15301588947620762 6.621179570570157 0.015373390576825229 0.015570878720764325 2.638272996869639e-07 6.578680267584285 0.11139111406670499 AYSSFGGGR ddPTM_PC-9_Lapatinib_30min_R1 1 AYSSFGGGR 9 0 Q15056;Q15056-2 Q15056;Q15056-2 EIF4H Eukaryotic translation initiation factor 4H 0 95.815 0.024442 4972900.0 7930.5 8497.3 10256.0 6780.0 11424.0 9924.2 11869.0 7371.5 8435.2 6170.4 False True 7817.409615724418 8477.625023922554 9412.791269304877 7278.623817416973 10752.062780448152 9499.765100440127 12483.518744536981 7714.006800983797 7485.138949406142 7236.9454184588185 1.080208453111315 1.171436916229769 1.3006580435574746 1.005759114729793 1.4857183740841193 1.312676074108515 1.7249706917363312 1.0659202681435413 1.03429534376676 1.0 12.821165175405444 -7.968558503191267 24.999982936171012 1.0281330411120515 1.2968365433788602 0.2866294203481119 0.19168959205343605 250.13771063868285 198891.12884448454 0.10840894194922225 0.052077244011897 1.0750817679037059e-08 7.968558503191267 0.2687035022668087 AYSSFGGGRGS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 AYSSFGGGRGSR 12 1 Q15056;Q15056-2 Q15056;Q15056-2 EIF4H Eukaryotic translation initiation factor 4H 1 AYSSFGGGRGS(1)R;AYSSFGGGRGS(1)R 86.539 0.004278100000000001 63807000.0 45530.0 54989.0 67515.0 116446.0 103507.0 77692.0 57329.0 92232.0 57838.0 77639.0 True False 60007.59291716855 72763.11888149632 66619.70698648269 89601.173772766 89136.83971087352 72833.90695821728 62431.16993901108 77979.6636805132 60895.19860138273 74920.88224147238 0.8009461597604013 0.9711994400570255 0.8892007807885292 1.1959439223363462 1.1897462635795273 0.9721442777925557 0.8332946445797773 1.0408268208746163 0.8127933999110631 1.0 16.19308026789046 -10.566850902108445 13.887896007342025 1.0000001468694157 0.9767836258543501 0.0008587493236368315 0.13550277093666152 0.0 0.0 0.13769262102702767 0.033395365903681085 2.7111222290914415e-11 10.566850902108445 -0.02321652101506566 AYSSFGGGRGS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AYSSFGGGRGSR 12 1 Q15056;Q15056-2 Q15056;Q15056-2 EIF4H Eukaryotic translation initiation factor 4H 1 AYSSFGGGRGS(0.999)R;AYSSFGGGRGS(1)R;AYSSFGGGRGS(1)R 86.288 0.029643 29378600.0 127530.0 112494.0 163906.0 143397.0 184009.0 152850.0 122215.0 168809.0 104887.0 100352.0 True False 149118.31016768562 123661.660873054 167814.1406569663 135362.93098934676 147953.75736965926 144834.27692295337 110637.91044002384 164377.94261792037 106420.77394829119 118545.02321400518 1.2579044326347428 1.0431619777897545 1.4156152329905687 1.1418693701293625 1.2480807153123883 1.2217659838953265 0.9332986526165092 1.3866287943710183 0.8977245190308284 1.0 16.855075570954007 -8.15325832287365 0.7097101211154951 0.9817985393426224 1.217776898801644 0.21956587027273833 0.15233046116869722 1.0652755529805753 1.1668003318244988 0.13834631077773935 0.059371314874999366 7.026542495060174e-09 8.15325832287365 0.23597835945902157 AYSSFGGGRGS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 AYSSFGGGRGSR 12 1 Q15056;Q15056-2 Q15056;Q15056-2 EIF4H Eukaryotic translation initiation factor 4H 1 AYSSFGGGRGS(1)R 71.031 0.013384 33818000.0 49902.0 48893.0 61296.0 50839.0 48964.0 36668.0 28015.0 35069.0 44852.0 36464.0 True False 49190.38832909401 48779.79126247696 56256.47948940243 54577.86965393236 46084.033786927816 35099.79511728284 29465.479621552247 36698.433765678725 39800.29544750148 42766.75381477411 1.1502015921559332 1.140600745002666 1.3154255226630784 1.2761751778101524 1.0775667937417248 0.8207261946815646 0.6889809722096132 0.8581066013245309 0.9306363447616208 1.0 15.38420208400329 -6.600997884865168 3.4847937109194507 0.8403980516042657 1.2191893667526714 0.7790688263324224 0.09056535051640743 0.10939118181629587 2.6549868279422255 0.0328658905473607 0.0332484025348467 2.506121458510429e-07 6.600997884865168 0.3787913151484057 AYT(ph)HQVVTR ddPTM_PC-9_AZD4547_30min_R2 1 AYTHQVVTR 9 0 D6REC6;D6R9G1;D6RAD4;P50613 D6REC6 CDK7 Cyclin-dependent kinase 7 1 AYT(0.999)HQVVT(0.001)R 105.36 0.0064586 26162000.0 19995.0 16503.0 30018.0 24661.0 31596.0 25150.0 24455.0 30563.0 25481.0 30203.0 True False 26352.994078163552 21837.272016245686 29619.94170658724 18975.787458651896 27209.440786659394 23577.366524213117 26631.447624387572 25840.190617871503 26827.873639507485 29145.60216307771 0.904184237838397 0.7492475843888936 1.016274823929026 0.6510686364439174 0.9335693472522901 0.8089510860777975 0.9137381164876008 0.8865896979341338 0.9204775900459392 1.0 14.8309905883207 -8.408515058074531 0.654127060654812 0.9993793651220491 0.8404733318920549 0.19707178894660926 0.09557839781459834 1.1793075690944002 1.1803624248630393 0.08836397091263426 0.037523480941753805 3.903776469048447e-09 8.408515058074531 -0.1589060332299942 AYT(ph)HQVVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 AYTHQVVTR 9 0 D6REC6;D6R9G1;D6RAD4;P50613 D6REC6 CDK7 Cyclin-dependent kinase 7 1 AYT(1)HQVVTR;AYT(0.999)HQVVT(0.001)R 88.803 0.024051 39740000.0 39291.0 49528.0 50950.0 54550.0 70027.0 60231.0 55726.0 52182.0 54064.0 46851.0 True False 45942.19026737651 54444.8125208511 52164.84122895103 51493.74035348617 56305.71204302563 57072.380329384345 50447.22985869797 50812.2777913992 54854.58372096071 55344.715427688054 0.8301097930009842 0.9837400391368396 0.9425442126829298 0.9304183778985464 1.0173638369609685 1.0312164384322042 0.9115094272119076 0.9181053222288077 0.9911440197507613 1.0 15.756157947861698 -4.7570315991308725 24.976666103717765 0.966540086629131 0.8301095879390445 0.5205901752768194 0.04005212287624361 116.19165164460394 658315.8243750235 0.010507915156577865 0.08082225410175874 1.74971937495778e-05 4.7570315991308725 -0.1364304986900865 AYT(ph)HQVVTR ddPTM_PC-9_Lapatinib_30min_R1 1 AYTHQVVTR 9 0 D6REC6;D6R9G1;D6RAD4;P50613 D6REC6 CDK7 Cyclin-dependent kinase 7 1 AY(0.004)T(0.995)HQVVTR 117.86 0.004481000000000001 30592000.0 35525.0 39425.0 42181.0 29151.0 42792.0 25492.0 35720.0 45605.0 33191.0 36171.0 True False 35018.40698551289 39333.713834764756 38713.04100336866 31294.86178488527 40275.058692308936 24401.766584754427 37569.40682069767 47723.97478923778 29452.680063275235 42423.109155172075 0.8254559291593924 0.9271765935611377 0.9125460574274976 0.7376843048070161 0.9493660293731381 0.5751998632514055 0.885588245860979 1.1249523134826491 0.6942602899647319 1.0 15.37256273823905 -10.660068614295033 5.186235848321823 1.0000031555925006 0.8532118322471082 0.08918995832731502 0.14484520515865035 8.08816383974275e-06 1.3455017387366322e-06 0.1376674864897004 0.03338815103885852 2.187416006240111e-11 10.660068614295033 -0.14679132334539247 AYT(ph)PPPPLGPHPNLGK ddPTM_PC-9_AZD4547_30min_R2 2 AYTPPPPLGPHPNLGK 16 0 J3QS41;P42694 J3QS41 HELZ Probable helicase with zinc finger domain 1 AY(0.104)T(0.896)PPPPLGPHPNLGK;AY(0.003)T(0.997)PPPPLGPHPNLGK 114.56 0.00040067 42963000.0 275202.0 256894.0 364782.0 436390.0 434460.0 386230.0 358730.0 395440.0 339030.0 388980.0 True False 362710.5114427985 339929.96166402614 359944.7523356751 335787.02765829064 374142.7283254856 362078.97704361123 390656.2750479074 334333.8343072051 356950.43365653727 375361.9285962965 0.9662954173301238 0.9056058586847852 0.9589271711218145 0.8945686871175237 0.9967519341256311 0.9646129494209543 1.0407455985448646 0.8906972413464518 0.9509500204013474 1.0 18.517922805450944 -6.271878239118641 24.749493989580564 0.9713664496758949 0.9314803152474475 0.2002168026568637 0.0415272316215587 1121.4748800592802 2658897.33389877 0.012842846547260726 0.014710734462686663 5.34714253433033e-07 6.271878239118641 -0.03988613442844746 AYT(ph)PPPPLGPHPNLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AYTPPPPLGPHPNLGK 16 0 J3QS41;P42694 J3QS41 HELZ Probable helicase with zinc finger domain 1 AY(0.027)T(0.973)PPPPLGPHPNLGK 98.07700000000001 0.0044045 14031000.0 83761.0 93933.0 92533.0 105220.0 113050.0 121690.0 108190.0 101070.0 88491.0 82901.0 True False 97940.08294484028 103258.04745842984 94739.3376533565 99324.8645278425 90898.66403621538 115308.36217699824 97941.45997223082 98417.01959251687 89785.0134664755 97930.295056045 1.000099947506435 1.054403516290192 0.9674160340182543 1.014240429593308 0.9281975918095065 1.1774534337000402 1.0001140088077896 1.0049701120188939 0.9168257219596041 1.0 16.579467610839544 -8.068060095481547 5.873519429898669 0.9579468015215521 1.0206405049239187 0.12529237408115101 0.06439454144744974 0.46742751511726816 30.086197224161292 0.04363143462639395 0.016284274930335112 8.549484012483917e-09 8.068060095481547 0.06269370340236657 AYT(ph)PPPPLGPHPNLGK ddPTM_PC-9_Lapatinib_30min_R1 2 AYTPPPPLGPHPNLGK 16 0 J3QS41;P42694 J3QS41 HELZ Probable helicase with zinc finger domain 1 AY(0.014)T(0.986)PPPPLGPHPNLGK;AY(0.015)T(0.985)PPPPLGPHPNLGK 117.07 0.00031195 44282000.0 340010.0 278330.0 264710.0 252730.0 256130.0 251340.0 237830.0 212575.0 254830.0 197652.0 True False 335161.3950498029 277685.5439855446 242946.56561014956 271316.60728256585 241064.93697095488 240590.77410215678 250143.67368887292 222452.01054319058 226128.3619211362 231815.8848452651 1.4458085789656734 1.1978710784677118 1.0480151770976096 1.1703969616390486 1.039898267247145 1.037852838526354 1.0790618332986173 0.959606416495898 0.9754653442842139 1.0 17.822619902741053 -1.5228787452803438 0.6063604192713931 1.0153072202965092 28.59744421243946 0.8658216972616027 0.05045700884879613 62.255173425306836 0.47170451187259516 0.023514820664911704 2279.2686218818594 0.029999999999999565 1.5228787452803438 27.58213699214295 AYT(ph)PVVVTLWYR ddPTM_PC-9_AZD4547_30min_R2 2 AYTPVVVTLWYR 12 0 P21127;P21127-8;A0A0D9SEN2;A0A0D9SER5;A0A0D9SEI3;P21127-9;P21127-2;P21127-3;P21127-6;P21127-10;P21127-5;P21127-4;P21127-12 P21127 CDK11B Cyclin-dependent kinase 11B 1 AYT(1)PVVVTLWYR;AYT(1)PVVVTLWYR 198.52 2.0769e-05 12309800.0 30352.0 37489.0 37449.0 28455.0 29569.0 37520.0 40929.0 42233.0 37656.0 33024.0 True False 40003.304639180795 49606.58611264824 36952.401791258075 21895.13937536758 25463.85474809254 35173.868468726694 44571.60171002085 35706.86026779333 39646.41928375237 31867.83981172329 1.2552876152108903 1.5566347265998042 1.1595515105377276 0.6870606700901317 0.7990455235916273 1.1037418499821632 1.3986389404914794 1.1204669183336917 1.2440886962525637 1.0 14.95981360768502 -5.508962783981911 24.04736271380757 1.0510628389018657 1.3939942940006698 0.3247276343703268 0.20247698761721128 488.82917911174377 844714.3655190822 0.05989448120297971 0.11694153805529989 3.0976847378916902e-06 5.508962783981911 0.34293145509880407 AYT(ph)PVVVTLWYR ddPTM_PC-9_Lapatinib_30min_R1 2 AYTPVVVTLWYR 12 0 P21127;P21127-8;A0A0D9SEN2;A0A0D9SER5;A0A0D9SEI3;P21127-9;P21127-2;P21127-3;P21127-6;P21127-10;P21127-5;P21127-4;P21127-12 P21127 CDK11B Cyclin-dependent kinase 11B 1 AYT(1)PVVVTLWYR;AYT(1)PVVVTLWYR 184.34 0.0011952999999999998 36993000.0 51406.0 91436.0 86244.0 77961.0 95250.0 95021.0 94584.0 94788.0 76213.0 76063.0 True False 50672.941013294185 91224.28555981096 79153.35123146737 83694.51201027211 89647.58226870517 90957.17333476961 99481.09671693375 99192.19652060675 67629.08938153097 89210.3882024233 0.568016147383133 1.0225746955928272 0.8872660777113092 0.9381700236564898 1.0049007080351433 1.019580512623516 1.1151290642431197 1.1118906499491312 0.7580853614051856 1.0 16.444924095698354 -4.75866696494512 24.996462609304672 0.9890540280279299 0.5680155829523513 0.6095504515450867 0.0998532439696722 51.88244067205104 467690.11355939956 0.025079578916571477 0.16882248470530753 1.7431430755412893e-05 4.75866696494512 -0.4210384450755785 AYT(ph)PVVVTQWYR ddPTM_PC-9_AZD4547_30min_R2 4 AYTPVVVTQWYR 12 0 Q5QPR4;Q5QPR3;Q9UQ88-4;Q9UQ88-3;Q9UQ88-2;Q9UQ88;Q9UQ88-5;Q9UQ88-10 Q5QPR4 CDK11A Cyclin-dependent kinase 11A 1 AYT(1)PVVVTQWYR;AYT(1)PVVVTQWYR;AY(0.001)T(0.999)PVVVTQWYR;AYT(0.998)PVVVT(0.002)QWYR 143.76 0.00021593 92479000.0 78874.40000000001 82502.59999999999 93673.0 102700.4 93869.4 96420.4 93164.4 102571.9 97407.0 92259.3 True False 103954.81851056285 109169.95202372369 92430.8348151492 79024.40948536282 80837.25411378822 90391.2171455761 101455.85111664252 86721.76972277781 102555.7351596682 89029.3299885456 1.1676468701262555 1.2262245715852218 1.0382065643652627 0.8876221970392228 0.9079845273932605 1.0152970617346633 1.1395778349640022 0.9740808982156253 1.1519320113142812 1.0 16.441993078080387 -5.327737981447047 5.325456743194861 1.0082292855196553 1.1967064922599966 0.44812959526715124 0.08118996387539543 0.18238010789815393 10.110681831372379 0.02274656092801359 0.049505048225837685 4.701776906622161e-06 5.327737981447047 0.1884772067403413 AYT(ph)PVVVTQWYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 AYTPVVVTQWYR 12 0 Q5QPR4;Q5QPR3;Q9UQ88-4;Q9UQ88-3;Q9UQ88-2;Q9UQ88;Q9UQ88-5;Q9UQ88-10 Q5QPR4 CDK11A Cyclin-dependent kinase 11A 1 AY(0.003)T(0.993)PVVVT(0.004)QWYR;AYT(1)PVVVTQWYR;AYT(1)PVVVTQWYR 143.76 0.00016612 67344000.0 57630.0 66412.0 64239.0 63730.0 72135.0 45554.2 62887.0 53088.0 47994.0 46177.0 True False 67385.62075561598 73004.94445838223 65770.70138776423 60159.41471544774 58000.66457543019 43165.25755841411 56929.88809754764 51694.496251385564 48695.82145427251 54548.524563069106 1.2353335180991851 1.3383486545813679 1.2057283293101726 1.1028605300935557 1.0632856716109658 0.791318516938187 1.0436558743532136 0.9476790924311123 0.8927064818768895 1.0 15.735252554387415 -6.003939058819853 1.4232555275712468 0.940630532329559 1.2874687459643994 0.7815525531008717 0.07359186371635922 0.18007612300796744 0.7388976618852906 0.025548337281229152 0.04543166890375064 9.909709904189384e-07 6.003939058819853 0.34683821363484046 AYT(ph)PVVVTQWYR ddPTM_PC-9_Lapatinib_30min_R1 2 AYTPVVVTQWYR 12 0 Q5QPR4;Q5QPR3;Q9UQ88-4;Q9UQ88-3;Q9UQ88-2;Q9UQ88;Q9UQ88-5;Q9UQ88-10 Q5QPR4 CDK11A Cyclin-dependent kinase 11A 1 AYT(0.995)PVVVT(0.005)QWYR;AYT(1)PVVVTQWYR 161.25 0.00034045 35839200.0 37306.2 50161.0 55462.0 42121.0 56346.0 43833.0 46487.0 45442.0 45702.0 35936.0 True False 36774.20674688081 50044.85528638264 50902.128449511234 45218.718851536934 53031.839060498234 41958.36476971364 48893.869397362076 47553.40121417701 40554.55949660464 42147.48971828991 0.8725123843122414 1.1873745179339985 1.207714357123913 1.0728686133806509 1.2582443086162036 0.9955127826155161 1.1600659902680888 1.1282617667628543 0.9622058103025288 1.0 15.363159087138595 -8.259307904380353 24.750472824638226 0.9811028922438476 1.1176481607124733 0.18955823862413435 0.1060098545817008 238.14641474050887 2765435.1938557383 0.07646931700153341 0.025704563625575577 5.504173253462738e-09 8.259307904380353 0.1365452684686257 AYTHQVVT(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 AYTHQVVTR 9 0 D6REC6;D6R9G1;D6RAD4;P50613 D6REC6 CDK7 Cyclin-dependent kinase 7 1 AYT(0.203)HQVVT(0.797)R 84.916 0.031392 29099000.0 33319.0 40363.0 31804.0 34304.0 47526.0 21985.0 31761.0 41443.0 21128.0 30051.0 True False 32843.86495004371 40269.54195339534 29189.19788699027 36826.83059478936 44730.61411971105 21044.752799538106 33405.42917223348 43368.59307510976 18748.34215229669 35245.275309559496 0.9318657511276566 1.1425514937734966 0.828173354602038 1.0448728310770465 1.2691236974840387 0.5970942946168499 0.9477987866127692 1.2304796229906876 0.5319391602882902 1.0 15.105142254243422 -6.749371485711075 24.999907119168874 0.8812633149212993 1.0369642972709225 0.14813724417394958 0.21517563799285574 526.0482523224647 1089762.458023153 0.07005854351712856 0.06954693084180959 1.7808548126953882e-07 6.749371485711075 0.15570098234962326 AYTNFDAER ddPTM_PC-9_AZD4547_30min_R2 1 AYTNFDAER 9 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 119.75 0.0079191 86745000.0 212830.0 228750.0 266920.0 265060.0 292460.0 274260.0 234810.0 348180.0 309610.0 286430.0 False True 280505.5128609921 302688.9640499426 263380.4663975704 203954.5121361776 251856.97722706743 257110.47884416254 255707.6351127558 294376.7813804443 325975.3525186575 276402.17288250726 1.0148455416818634 1.0951034172173795 0.9528885523976248 0.7378904080572274 0.9111975300357951 0.9302042605629399 0.9251288889883356 1.065030633842295 1.1793516278080156 1.0 18.076409431677078 -7.831255649312378 4.648419403807838 1.0985391065406804 0.935584010310648 0.3274875912958306 0.09400327194104376 0.2547289548648511 10.397895319344531 0.058713301666453756 0.027509505710297144 1.474838107912104e-08 7.831255649312378 -0.16295509623003246 AYTNFDAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 AYTNFDAER 9 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 131.12 0.0057319 6755700.0 23831.0 33897.0 36794.0 30981.0 49698.0 27715.0 30621.0 27083.0 27236.0 25021.0 False True 27865.117616295094 37262.07014253131 37671.30850202205 29245.235011757202 39960.03366007811 26261.57661053092 27720.357203158153 26372.09994681047 27634.27497455027 29557.109233872998 0.9427551725647497 1.2606804626153454 1.2745261454340748 0.9894484193414158 1.3519601441362596 0.8885028776912548 0.9378575213096316 0.8922421925005966 0.9349451178020101 1.0 14.851217556411997 -6.786800860775155 24.99958943421239 0.924421332097841 1.1657092799851605 0.4840273905902358 0.12027285545937424 187.10461842081537 184433.38177778298 0.04047768539006769 0.03571109511604153 1.6338009310908918e-07 6.786800860775155 0.24128794788731944 AYTNFDAER ddPTM_PC-9_Lapatinib_30min_R1 3 AYTNFDAER 9 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ;; 148.69 0.0014385 253642100.0 858480.0 1131261.0 963586.0 1230915.0 1063065.0 1013645.0 1056582.0 940332.0 1219584.0 1009281.0 False True 846237.9177740496 1128641.63465897 884363.6786295238 1321440.5953120657 1000537.6067662043 970293.7662719055 1111286.6460645683 984023.2575707389 1082221.6071311347 1183733.876067604 0.7148886543530163 0.9534589298131334 0.7470967051879971 1.116332498400677 0.8452386359762022 0.8196891090886473 0.938797704899933 0.8312875701755625 0.9142440112690736 1.0 20.17491334384509 -11.201027646313664 0.01582122111426358 1.9262371077154958 3.1166717277008586e-06 0.12853709360644394 0.10715843469248137 6608.146254978648 15.873659768671681 1085.8051407518396 856.4863959491543 6.294661110345409e-12 11.201027646313664 -1.926233991043768 AYTS(ph)EDEAWK ddPTM_PC-9_Lapatinib_30min_R1 2 AYTSEDEAWK 10 0 Q6ISB3-2;Q6ISB3 Q6ISB3-2 GRHL2 Grainyhead-like protein 2 homolog 1 AYT(0.259)S(0.741)EDEAWK;AYT(0.194)S(0.806)EDEAWK 96.229 0.0056113 4610700.0 43941.0 65257.0 63413.0 57642.0 61766.0 65724.0 62637.0 70158.0 61324.0 51597.0 True False 43314.393282207515 65105.90142587814 58199.42792125874 61881.184968075126 58133.045316628246 62913.13773012708 65880.0373748051 73417.79680437114 54417.04534965171 60515.472701319086 0.7157573319469975 1.075855455136501 0.961728056037975 1.0225679847779867 0.9606311034460628 1.0396206940436858 1.0886478190456088 1.213207028336917 0.899225320741245 1.0 15.885016439878918 -4.756774151014314 24.99175309822109 1.0334641676608207 0.7157568509509235 0.5685762606268481 0.08179061571139043 104.34575506912238 558915.2658388541 0.020346915462117456 0.16009363030203666 1.750756909439148e-05 4.756774151014314 -0.31770731670989727 CAAPRPPSS(ph)SPEQR ddPTM_PC-9_AZD4547_30min_R2 2 CAAPRPPSSSPEQR 14 1 H0YEN2;E9PQP7;H7BXH2;E9PKF6;Q5H9R7-4;Q5H9R7-6;Q5H9R7-2;Q5H9R7;Q5H9R7-5 H0YEN2 PPP6R3 Serine/threonine-protein phosphatase 6 regulatory subunit 3 1 CAAPRPPS(0.027)S(0.824)S(0.149)PEQR;CAAPRPPS(0.038)S(0.864)S(0.097)PEQR 71.976 0.011254 8726600.0 14653.9 13238.3 19096.2 19830.8 23116.3 21272.8 17952.8 23294.0 18130.4 21543.1 True False 19313.535379945028 17517.321585933776 18842.971910764583 15259.115442805822 19907.00076138293 19942.60845313243 19550.564420818046 19694.44754286879 19088.7359300548 20788.882626209295 0.9290319122585143 0.8426292985967921 0.9063965702037573 0.7340036363266635 0.9575791599441451 0.9592919836869954 0.9404336333194716 0.9473547903935582 0.918218466729373 1.0 14.343524596959389 CAAPRPPSS(ph)SPEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 CAAPRPPSSSPEQR 14 1 H0YEN2;E9PQP7;H7BXH2;E9PKF6;Q5H9R7-4;Q5H9R7-6;Q5H9R7-2;Q5H9R7;Q5H9R7-5 H0YEN2 PPP6R3 Serine/threonine-protein phosphatase 6 regulatory subunit 3 1 CAAPRPPS(0.188)S(0.682)S(0.131)PEQR;CAAPRPPS(0.319)S(0.608)S(0.073)PEQR 65.105 0.018732 8413000.0 16448.8 19318.4 22501.0 23827.0 23186.2 24735.0 22691.0 19104.8 20849.0 16574.2 True False 19233.256961391227 21236.203081142186 23037.509175517687 22492.05043817626 18643.030553529356 23437.8530565211 20541.54421138636 18603.319243208833 21153.877182567132 19578.971258704994 0.9823425708763907 1.0846434575412316 1.1766455382723437 1.1487861206280734 0.9521966352159841 1.1970931846636432 1.0491636123247996 0.9501683718411723 1.0804386452716161 1.0 14.257017342705806 -7.521281391466319 24.99843783291231 1.0091152906778749 1.093068795130412 0.1735531487824833 0.07856949989505196 107.49339942692941 1682342.2568844995 0.0360950882907654 0.021203419106475465 3.0110544461437183e-08 7.521281391466319 0.08395350445253724 CAAPRPPSS(ph)SPEQR ddPTM_PC-9_Lapatinib_30min_R1 2 CAAPRPPSSSPEQR 14 1 H0YEN2;E9PQP7;H7BXH2;E9PKF6;Q5H9R7-4;Q5H9R7-6;Q5H9R7-2;Q5H9R7;Q5H9R7-5 H0YEN2 PPP6R3 Serine/threonine-protein phosphatase 6 regulatory subunit 3 1 CAAPRPPS(0.018)S(0.793)S(0.189)PEQR;CAAPRPPS(0.245)S(0.643)S(0.112)PEQR 83.25200000000001 0.0039096 33734600.0 22442.9 15992.5 13799.5 17901.4 18977.5 20753.0 14364.699999999999 16275.2 20114.3 14173.2 True False 22122.8601304762 15955.470348826268 12664.958377610441 19217.928673319813 17861.280761200527 19865.442567605853 15108.433878983098 17031.405207538694 17848.815721030904 16623.018735398105 1.330856957007838 0.9598419277991718 0.7618928053447284 1.1561034117344728 1.074490803716992 1.1950562580611863 0.9088862931261844 1.0245675276338915 1.0737409375002693 1.0 14.020894778451984 -8.347188708730819 0.007346726063707344 6.370215453291271e-07 2.058299918042142 0.022905950894095528 0.14877085012008598 17385.847850418962 100.79693930481463 14210.716918732971 14017.435165415596 4.4958445994493064e-09 8.347188708730819 2.058299281020597 CAAPRPPSSS(ph)PEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CAAPRPPSSSPEQR 14 1 H0YEN2;E9PQP7;H7BXH2;E9PKF6;Q5H9R7-4;Q5H9R7-6;Q5H9R7-2;Q5H9R7;Q5H9R7-5 H0YEN2 PPP6R3 Serine/threonine-protein phosphatase 6 regulatory subunit 3 1 CAAPRPPS(0.017)S(0.118)S(0.865)PEQR 116.9 0.0006653 7373900.0 7481.7 6480.7 4835.0 4851.3 8231.2 5238.3 6986.0 4913.0 6049.4 4647.4 True False 8748.204039689263 7124.061066545789 4950.284736839609 4579.497389126809 6618.355448163603 4963.594326499881 6324.235505739941 4784.038955753793 6137.86103065958 5489.936831201845 1.5934981236886336 1.2976581125772635 0.9017015840154764 0.8341621278954271 1.2055430966980227 0.9041259451820072 1.1519687202585631 0.8714196725477589 1.118020337825252 1.0 12.422573833922408 -4.983402965377906 3.0540257917747726 0.9985663715970955 1.5901912253961954 0.7112853090480579 0.12085507319474208 0.13826905177760426 2.4455205178504342 0.030262488772696786 0.15818866116716565 1.0389557108588996e-05 4.983402965377906 0.5916248537990999 CAAPRPPSSS(ph)PEQR ddPTM_PC-9_Lapatinib_30min_R1 1 CAAPRPPSSSPEQR 14 1 H0YEN2;E9PQP7;H7BXH2;E9PKF6;Q5H9R7-4;Q5H9R7-6;Q5H9R7-2;Q5H9R7;Q5H9R7-5 H0YEN2 PPP6R3 Serine/threonine-protein phosphatase 6 regulatory subunit 3 1 CAAPRPPS(0.021)S(0.195)S(0.784)PEQR 107.46 0.0037551999999999998 3315200.0 5555.5 5584.8 7765.7 6649.6 6345.3 7679.3 5785.2 4332.7 8370.6 5701.4 True False 5476.277551246072 5571.868738729086 7127.234122468882 7138.633766415331 5972.081929339787 7350.874240322632 6084.729348799003 4534.013059298992 7427.814881674297 6686.879393362031 0.8189586246586553 0.8332539606232766 1.065853547402692 1.0675583252633134 0.8931044778926606 1.099298164046407 0.9099505151594668 0.6780461845625392 1.1108043744661795 1.0 12.707117381318783 -5.152680394989151 8.064423699027566 0.9685237232360698 0.8233097671896326 0.19351732518767095 0.12294928740931131 0.5088583959849696 33.90089161660202 0.031903388188304384 0.08534599637598689 7.0358991370193365e-06 5.152680394989151 -0.14521395604643728 CADTRPGSEQPPLGGAAS(ph)PEVLAPVSK ddPTM_PC-9_Lapatinib_30min_R1 1 CADTRPGSEQPPLGGAASPEVLAPVSK 27 1 Q96RY5 Q96RY5 CRAMP1L Protein cramped-like 1 CADT(0.001)RPGSEQPPLGGAAS(0.996)PEVLAPVS(0.003)K 63.906000000000006 0.00024471 5972700.0 45431.0 48823.0 48862.0 44282.0 48962.0 53141.0 39669.0 45096.0 48980.0 41039.0 True False 44783.14560897497 48709.95334317618 44844.75497277443 47538.64600042161 46082.15142299567 50868.28330772143 41722.86671809231 47191.32479104192 43463.35661773436 48132.53646896979 0.9304131652784575 1.0119963940520493 0.9316931594013349 0.9876613510918743 0.9574012674919808 1.0568377866501037 0.8668329113507308 0.9804454170302318 0.9029932724562403 1.0 15.554724831416184 -10.405832892340648 5.147337522470089 1.000000069503662 0.9609321312194321 0.05271490864429085 0.051875851308383014 3.888346537911726e-08 8.468481179055648e-09 0.04718191816411151 0.01144327555014669 3.927960462332045e-11 10.405832892340648 -0.03906793828422983 CAGNEDIITLR ddPTM_PC-9_Lapatinib_30min_R1 1 CAGNEDIITLR 11 0 P12004 P12004 PCNA Proliferating cell nuclear antigen 0 95.48299999999999 0.028567000000000002 3584500.0 36745.0 24969.0 28603.0 21784.0 32544.0 25358.0 29725.0 31161.0 27327.0 29259.0 False True 36221.00956179226 24911.18581459079 26251.371750772938 23386.06802929372 30629.825903965757 24273.497452385156 31264.015054457963 32608.85381882333 24249.145493932774 34316.37916483317 1.0555020792785426 0.7259269894103322 0.7649808164398326 0.6814841366847747 0.8925716130143088 0.7073443656683983 0.9110522676150165 0.9502416808659206 0.706634734901836 1.0 15.066609716870662 -7.294907235222143 24.89704108746118 0.8878356582956103 0.7976542247955742 0.10487308064570111 0.12377668639475899 1438.639605533607 1070211.4553311435 0.0500850322132069 0.033769436647355926 5.0709901244529776e-08 7.294907235222143 -0.09018143350003605 CALGWDHQEK ddPTM_PC-9_Lapatinib_30min_R1 1 CALGWDHQEK 10 0 Q14247-3;Q14247;Q14247-2 Q14247-3 CTTN Src substrate cortactin 0 84.65799999999999 0.012159 0.0 26426.0 27577.0 29154.0 24010.0 23981.0 25791.0 23411.0 24755.0 27524.0 24803.0 False True 26049.16039406513 27513.147150825844 26757.07065769445 25775.775495012025 22570.484728460015 24687.979051757444 24623.10702909723 25905.207672570556 24423.957279430786 29090.165502079926 0.895462777350051 0.9457886084855266 0.9197978146869373 0.886064931228015 0.7758802447117821 0.8486709726691748 0.8464409398886609 0.8905142760606966 0.8395949922555267 1.0 14.828243883906223 -5.913629083624914 4.488615283530851 0.8572834995348889 0.9221887970336851 0.1441708331946684 0.05476713495639626 0.31689310235331936 11.620599892429102 0.015011863013704146 0.0227634026430948 1.2200311418348356e-06 5.913629083624914 0.06490529749879614 CALSS(ph)PSLAFTPPIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CALSSPSLAFTPPIK 15 0 Q8NFH5-2;Q8NFH5;Q8NFH5-3 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 CALS(0.117)S(0.502)PS(0.369)LAFT(0.011)PPIK 99.669 0.0020172000000000002 5222800.0 16460.0 14007.0 14598.0 16857.0 23901.0 20050.0 24169.0 21612.0 21406.0 20086.0 True False 19246.352900181148 15397.522390961904 14946.071683223294 15912.55694113138 19217.770624764107 18998.54270399224 21879.537351593 21044.70789980683 21719.02225382666 23727.4327993115 0.8111435005619159 0.6489333473703356 0.6299068175490516 0.6706396379128347 0.8099388917170066 0.8006994631354944 0.9221198743518464 0.8869357286902729 0.915354915870076 1.0 14.534268395460318 -6.857881547234788 1.1323840199666622 0.9337357825047403 0.6826507847786828 0.7711642117930405 0.0573189478355028 0.23149233854510734 0.624117617991414 0.03221420704184115 0.026477099315275743 1.3871341147422705e-07 6.857881547234788 -0.2510849977260575 CALSSPSLAFT(ph)PPIK ddPTM_PC-9_AZD4547_30min_R2 2 CALSSPSLAFTPPIK 15 0 Q8NFH5-2;Q8NFH5;Q8NFH5-3 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 CALSSPS(0.001)LAFT(0.999)PPIK;CALSSPS(0.002)LAFT(0.998)PPIK 141.65 0.00020239 20146100.0 98076.0 86022.0 107753.0 131906.0 133427.0 115219.0 101233.0 129083.0 110986.0 122461.0 True False 129262.12789247131 113826.92924810557 106324.12481544062 101497.10962738485 114902.9641676672 108014.33771583719 110242.54088569338 109136.1883822498 116852.4933775903 118173.67766422768 1.0938318113425374 0.9632172874531948 0.8997276459275835 0.8588808576794341 0.9723228255123472 0.9140304325870546 0.9328857581883048 0.9235236690555023 0.9888199782493753 1.0 16.85054919580412 -10.797353542304258 20.963711257490118 0.999999999916072 0.9443032139525833 0.052694360697163156 0.06020459603641742 0.0 0.0 0.05939471049369768 0.014405333233441016 1.594580532527664e-11 10.797353542304258 -0.055696785963488704 CALSSPSLAFT(ph)PPIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 CALSSPSLAFTPPIK 15 0 Q8NFH5-2;Q8NFH5;Q8NFH5-3 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 CALSSPS(0.17)LAFT(0.83)PPIK;CALSSPS(0.319)LAFT(0.681)PPIK 134.61 3.4394e-05 14741800.0 66657.0 65950.0 64061.0 91576.0 88994.0 76445.0 84259.0 77342.0 73282.0 60631.0 True False 77940.71356423902 72497.0801516342 65588.45719269536 86445.293613398 71556.2645487743 72436.08962626867 76277.37753766707 75311.85445062282 74353.61061407653 71622.92034526818 1.0882090982679153 1.012205028811336 0.9157467592289891 1.2069501382612788 0.9990693510377326 1.011353478426745 1.0649855824079977 1.0515049384690212 1.0381259275053947 1.0 16.128133723699946 -8.580019910925746 17.008191921418813 0.9999999986035943 1.042187948236304 0.032830417164574355 0.07040411327278694 2367.800730852693 704787.4140705715 0.06625890371423657 0.017107975363412076 2.630147405812988e-09 8.580019910925746 0.042187949632709554 CAPS(ph)AGSPAAAVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CAPSAGSPAAAVGR 14 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 CAPS(0.685)AGS(0.315)PAAAVGR 72.681 0.022226 5619200.0 10456.0 19427.0 14468.0 16578.0 18619.0 13011.0 16699.0 15538.0 14966.0 11105.0 True False 12225.994284586515 21355.58417142978 14812.97199019555 15649.188406601175 14970.740607609838 12328.68025544354 15117.149829709617 15130.14396387185 15184.849437109688 13118.248592868367 0.9319837322821494 1.6279295227748294 1.1291882361680892 1.192932752860678 1.141214888681753 0.939811451823373 1.1523756180324207 1.1533661568280718 1.157536337995974 1.0 13.67928749927314 -5.482190515169738 24.999832119525497 1.1123306106148214 1.3046072181474726 0.13376315259780658 0.1727508855091023 813.1825822959252 499637.62716740515 0.042124567824097785 0.0876727456796588 3.294651515593133e-06 5.482190515169738 0.1922766075326512 CAPS(ph)AGSPAAAVGR ddPTM_PC-9_Lapatinib_30min_R1 1 CAPSAGSPAAAVGR 14 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 CAPS(0.5)AGS(0.5)PAAAVGR 93.228 0.0038361999999999997 11854000.0 11177.0 9845.7 16043.0 13485.0 11831.0 11236.0 17497.0 11994.0 13107.0 9201.2 True False 11017.613930389232 9822.902886568003 14724.006467770876 14476.731884641282 11135.123840640941 10755.462472395277 18402.90904652148 12551.2850262497 11630.751637171177 10791.615160171674 1.0209420709377819 0.9102347276820182 1.3643932116957223 1.3414796274491116 1.031831072121349 0.9966499280005995 1.7052970082217724 1.1630589897768402 1.0777581913870022 1.0 13.397623185912375 -5.249439064978578 24.624831460733073 1.2242757412728948 0.9655883672183275 0.17762479105965412 0.20862458158751607 1024.7712090414393 2102834.8196742577 0.05401852344666572 0.14043057543169363 5.630681148537049e-06 5.249439064978578 -0.2586873740545673 CAPSAGS(ph)PAAAVGR ddPTM_PC-9_AZD4547_30min_R2 3 CAPSAGSPAAAVGR 14 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 CAPSAGS(1)PAAAVGR;CAPS(0.008)AGS(0.992)PAAAVGR;CAPS(0.13)AGS(0.87)PAAAVGR 188.09 3.868e-06 61422900.0 38197.0 33800.3 52292.0 57544.0 52512.0 45371.0 49628.0 57356.0 47344.0 51011.0 True False 50342.85145304392 44725.585974108275 51598.57391301417 44278.11984593752 45221.61522309974 42533.94419761722 54044.79585782488 48492.94810976143 49846.50718530837 49225.12041654001 1.0227065170596992 0.9085927184259389 1.0482163065603525 0.8995025196740756 0.9186694687679207 0.8640698862226752 1.0979108918475173 0.9851260433578836 1.0126233671651836 1.0 15.587107114861299 -7.26335049080475 24.999911683944394 1.0226755745116234 0.9436478771426376 0.30642130850518634 0.059164715159775935 227.16683811616426 2971618.3790842243 0.02377459071031363 0.01694030159830578 5.453175931288957e-08 7.26335049080475 -0.07902769736898574 CAPSAGS(ph)PAAAVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 CAPSAGSPAAAVGR 14 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 CAPS(0.234)AGS(0.766)PAAAVGR;CAPS(0.415)AGS(0.585)PAAAVGR;CAPS(0.014)AGS(0.986)PAAAVGR;CAPS(0.487)AGS(0.513)PAAAVGR 130.66 1.8785e-05 81956300.0 66613.0 82014.0 59258.0 78843.0 80828.0 63985.0 79453.0 69052.0 65685.0 62083.0 True False 77889.26523327857 90155.80790835674 60670.935457216445 74425.68232245476 64990.33362865289 60629.513960845055 71926.6366500938 67239.45816664163 66645.51886118871 73338.15645124245 1.0620564928580096 1.2293165286789722 0.8272765282496898 1.0148289229486607 0.8861735387616477 0.8267117268096791 0.9807532685650876 0.9168414018062285 0.9087427621049731 1.0 16.162276380094816 -5.260326673037138 24.99703616773305 0.9181890457102473 1.1456865164170082 0.6114809553825817 0.07189143887711377 57.132576624118364 1283447.7459259992 0.01750033168095313 0.04129226650227049 5.491276687771277e-06 5.260326673037138 0.22749747070676096 CAPSAGS(ph)PAAAVGR ddPTM_PC-9_Lapatinib_30min_R1 3 CAPSAGSPAAAVGR 14 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 CAPS(0.181)AGS(0.819)PAAAVGR;CAPS(0.01)AGS(0.99)PAAAVGR;CAPS(0.033)AGS(0.967)PAAAVGR 150.9 3.1506999999999995e-05 83964000.0 50469.0 63491.0 64519.0 51551.0 58788.0 59454.0 56472.0 57575.0 60946.0 49292.0 True False 49749.30280511892 63343.99049037539 59214.49687054224 55342.232509094756 55330.205421654966 56911.291014043185 59395.84384038188 60250.14468787115 54081.619690168176 57812.05652253855 0.8605350820848884 1.0956882404914996 1.0242586137280367 0.9572783920516491 0.9570703543487332 0.9844190716837034 1.0273954502418692 1.042172659337626 0.9354730300777999 1.0 15.819082773165206 -7.127239673818709 13.999733733625273 1.0049690542444014 0.9850663649763047 0.022889946148719642 0.06130220746085008 4.694857486736363 504.2076909621414 0.023251340863906553 0.018010667100749465 7.460369298581251e-08 7.127239673818709 -0.019902689268096685 CAPSAGS(ph)PAAAVGRES(ph)PGAAATSSSGPQAQQHR ddPTM_PC-9_Lapatinib_30min_R1 1 CAPSAGSPAAAVGRESPGAAATSSSGPQAQQHR 33 1 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 2 CAPS(0.246)AGS(0.869)PAAAVGRES(0.881)PGAAAT(0.003)S(0.001)SSGPQAQQHR 80.79 1.2143e-08 6683300.0 4031.3 4422.4 5972.6 4995.0 4397.0 5839.9 5940.2 4173.8 6262.7 3816.6 True False 3973.812922750122 4412.160204511449 5481.555882902722 5362.348962831534 4138.377104834606 5590.141090471808 6247.754490378174 4367.729985206022 5557.3287768453465 4476.294224700166 0.8877461407301257 0.985672519059443 1.224574526995015 1.1979438110305893 0.924509627182026 1.248832362185989 1.3957425890155077 0.9757468490576231 1.2415021215942506 1.0 12.128089151755038 -5.074806170761566 4.0844161886764 1.1554795762771242 0.9038959016289272 0.28817170121334323 0.1382304612589235 0.2604140274261521 8.054545180146144 0.03549681328447694 0.1160810047234058 8.417707471048002e-06 5.074806170761566 -0.251583674648197 CAPSAGSPAAAVGRES(ph)PGAAATSSSGPQAQQHR ddPTM_PC-9_AZD4547_30min_R2 3 CAPSAGSPAAAVGRESPGAAATSSSGPQAQQHR 33 1 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 CAPSAGSPAAAVGRES(0.975)PGAAAT(0.008)S(0.01)S(0.003)S(0.003)GPQAQQHR;CAPS(0.001)AGS(0.004)PAAAVGRES(0.822)PGAAAT(0.05)S(0.05)S(0.05)S(0.022)GPQAQQHR;CAPS(0.001)AGS(0.004)PAAAVGRES(0.994)PGAAATSSSGPQAQQHR 83.318 2.5434e-09 51764600.0 17397.45 11538.51 30187.5 49726.4 40573.7 33916.4 25847.0 44150.2 22124.0 35374.5 True False 22929.47721055994 15268.107709638904 29787.194025837907 38262.746745221506 34940.74210804161 31795.6021463945 28147.332927726256 37327.80106066652 23293.429472958833 34136.0495221598 0.6717085758759229 0.44727225098872203 0.8726022619137933 1.1208897128058948 1.0235731022524863 0.9314376616940993 0.8245632790476852 1.0935009054411746 0.6823703913904168 1.0 15.059008488162283 -5.384521642763773 5.088800146474023 0.9568308643638214 0.56332200478172 0.5826945560578396 0.13117755082466206 0.1390178885992723 5.125941922618876 0.03348293447547214 0.07196162725964764 4.125516773782183e-06 5.384521642763773 -0.39350885958210136 CAPSAGSPAAAVGRES(ph)PGAAATSSSGPQAQQHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 CAPSAGSPAAAVGRESPGAAATSSSGPQAQQHR 33 1 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 CAPSAGSPAAAVGRES(1)PGAAATSSSGPQAQQHR;CAPSAGSPAAAVGRES(0.492)PGAAAT(0.12)S(0.158)S(0.158)S(0.072)GPQAQQHR;CAPSAGSPAAAVGRES(0.999)PGAAATSSSGPQAQQHR;CAPSAGSPAAAVGRES(0.566)PGAAAT(0.076)S(0.105)S(0.105)S(0.147)GPQAQQHR 132.79 3.7213e-22 58851900.0 20901.600000000002 23863.800000000003 41361.2 47088.6 51493.5 37040.8 49814.0 42568.2 38863.0 36718.3 True False 24439.828054582395 26232.840353640084 42347.40787122452 44450.37840530101 41403.7183241827 35098.3152413983 45095.25729787141 41450.82985473613 39431.297853427364 43375.03712809714 0.5634537667923045 0.6047911907525996 0.9763082794871673 1.0247917085126204 0.9545517667663858 0.8091823676771585 1.039659220687098 0.95563791063329 0.909078134895356 1.0 15.404577372156744 -5.244925075776566 6.789659944406785 0.9570848901454644 0.5810017326028936 0.8533922250232019 0.062103444561123364 0.056112892113368444 12.76125242132802 0.016331723813421312 0.04102677233698634 5.6895107747600535e-06 5.244925075776566 -0.3760831575425708 CAPSAGSPAAAVGRES(ph)PGAAATSSSGPQAQQHR ddPTM_PC-9_Lapatinib_30min_R1 2 CAPSAGSPAAAVGRESPGAAATSSSGPQAQQHR 33 1 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 CAPSAGSPAAAVGRES(0.998)PGAAATS(0.001)S(0.001)SGPQAQQHR;CAPSAGSPAAAVGRES(0.993)PGAAAT(0.004)S(0.002)S(0.001)SGPQAQQHR 99.09299999999999 4.2956e-16 18760200.0 21511.3 14427.9 26173.5 20361.0 23518.4 24279.5 15449.3 18386.5 27112.1 16322.7 True False 21204.544917310723 14394.493083997528 24021.61586263175 21858.415862304882 22135.09395095342 23241.12238327887 16249.18915999454 19240.803913218293 24058.44979493007 19144.056946369383 1.1076306854243925 0.7519040046904689 1.2547818850480061 1.14178598212174 1.1562384092861402 1.2140123929001625 0.8487850409928995 1.0050536292866208 1.2567059250987387 1.0 14.224608973020034 -5.267406449212769 24.996740934354342 1.1070701823706723 0.9297673459426323 0.19680268864761719 0.14530049066794595 714.9491915356555 2995013.7997575956 0.038021670847543675 0.08260299331097382 5.402484764254849e-06 5.267406449212769 -0.17730283642804 CCLTYCFNKPEDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CCLTYCFNKPEDK 13 1 P62979;A0A2R8Y422 P62979 RPS27A Ubiquitin-40S ribosomal protein S27a;Ubiquitin;40S ribosomal protein S27a 0 77.185 0.021262 4387000.0 40740.0 27989.0 29122.0 37554.0 28099.0 23752.0 20899.0 22787.0 19981.0 26303.0 False True 47636.47734832199 30767.562947143066 29816.378925800018 35449.971131710736 22593.202660359257 22506.40330699371 18919.29542434285 22188.86539482223 20273.184324661812 31071.525685566583 1.5331232148169087 0.9902173217530572 0.9596045983557991 1.1409150451912968 0.7271352842147144 0.7243417505387718 0.6088949611229192 0.7141221715137552 0.6524682608063613 1.0 14.923305462494893 -1.5228787452992134 0.48200055897057154 0.7173127339009984 22.06466934054791 0.6928168117105431 0.14888584419617365 55.934931417400044 0.6236430443021199 0.08660550634708583 1197.654258057865 0.029999999998696104 1.5228787452992134 21.347356606646912 CCS(ph)PPNELGFR ddPTM_PC-9_AZD4547_30min_R2 1 CCSPPNELGFR 11 0 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 CCS(1)PPNELGFR 81.23899999999999 0.015277 2824300.0 21790.0 20881.0 23046.0 36545.0 33852.0 23992.0 25118.0 23754.0 23317.0 24737.0 True False 28718.766739844134 27630.374899789495 22740.394982011112 28120.11486462162 29152.234128053995 22491.776447273205 27353.45333998641 20083.365112617223 24549.489017401065 23870.965159356794 1.2030836016945519 1.1574888034621051 0.9526382712304144 1.1780049393436138 1.2212423726246813 0.9422231693240529 1.1458880341612232 0.8413302511459227 1.0284246511824977 1.0 14.542969278707627 -7.178961471145765 1.438010912101335 0.9687024707012386 1.1289192296574029 0.28305436713449295 0.10527872421187305 0.548765599292331 2.237825919260892 0.059489990283159974 0.03763984409044824 6.622752554842711e-08 7.178961471145765 0.16021675895616427 CCSGAIIVLT(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 CCSGAIIVLTK 11 0 P14618;P14618-3;B4DNK4 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 1 CCSGAIIVLT(1)K 82.54299999999999 0.03381 6032900.0 17945.0 18884.0 24116.0 37600.0 31696.0 27713.0 14777.0 23116.0 23899.0 21856.0 True False 23651.136720812436 24987.883703252948 23796.206082885514 28931.900914209156 27295.557512785046 25980.10172904645 16092.124373157854 19543.953352835724 25162.25234922451 21090.828092448643 1.1213944097946769 1.1847748980610016 1.1282727249294449 1.3717764322666843 1.2941908868224072 1.2318198989231894 0.762991585850509 0.9266565194674949 1.1930424087157392 1.0 14.364328120551855 -7.226748069661944 24.29725821890517 0.9645606679512692 1.2261683742746332 0.513098350568512 0.11985906619608076 358.54388456846993 251118.76681132618 0.047637231198034084 0.036897450874205 5.932693750293432e-08 7.226748069661944 0.26160770632336405 CCSGAIIVLTK ddPTM_PC-9_Lapatinib_30min_R1 2 CCSGAIIVLTK 11 0 P14618;P14618-3;B4DNK4 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ; 138.25 0.00045821 31710000.0 100041.0 84048.0 106507.0 85548.0 95354.0 80029.0 74329.0 85988.0 87933.0 85248.0 False True 98614.39699472763 83853.39201989381 97750.40558890914 91839.48529976224 89745.46519317706 76606.34622671072 78177.3919254099 89983.31639462736 78029.05956445976 99983.00321417996 0.9863116112193535 0.8386764682419683 0.9776702284038394 0.9185509771398547 0.8976072163078317 0.7661936905676597 0.7819068182813146 0.8999861326616522 0.7804232425116171 1.0 16.609395241809253 -6.538280535826057 23.519003289843035 0.8350679248591762 0.9247583100089991 0.21566463456829865 0.07483973698472002 164.69450634888713 251490.29562303933 0.02334326950179428 0.023353447543117238 2.89547263090324e-07 6.538280535826057 0.08969038514982286 CDDLTRR ddPTM_PC-9_AZD4547_30min_R2 3 CDDLTRR 7 1 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 ;; 99.375 0.0075057000000000006 4938500.0 21555.9 11989.8 21760.800000000003 44493.0 36607.2 28755.0 19463.600000000002 25798.0 23844.300000000003 24420.8 False True 28410.22780942663 15865.268376681955 21472.237573745875 34235.82625999754 31524.92216626784 26956.94530432398 21195.82269401064 21811.51187906453 25104.66101889676 23565.835225113005 1.2055684654516798 0.6732317452417338 0.9111596244576945 1.4527737265816927 1.3377383769819968 1.143899422482477 0.8994301492621507 0.9255564961186278 1.0652990135543297 1.0 14.524409194099185 -11.540332947540678 3.384305379845746 0.9262789977988218 1.064345900045383 0.008473360199501956 0.21789656441202113 0.21609582735785396 0.0011144939675460635 0.37615768618652773 0.056082764751941405 2.8818213363978068e-12 11.540332947540678 0.13806690224656115 CDDLTRR ddPTM_PC-9_Lapatinib_30min_R1 1 CDDLTRR 7 1 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 89.369 0.010533 1360200.0 10962.0 5246.8 7557.0 7754.2 6159.7 5340.1 4362.7 4592.8 8135.2 4322.0 False True 10805.679869815402 5234.65135696243 6935.692630863588 8324.469735252904 5797.398556436145 5111.716371381101 4588.579259144956 4806.198254840725 7218.928108546191 5069.051941297002 2.131696418768711 1.032668715488257 1.3682425651154357 1.6422143295542853 1.1436849776987654 1.0084166488286532 0.9052144882877037 0.948145394937693 1.4241179992129076 1.0 12.307500231597501 -6.399346905588522 4.885572078127198 1.0474504880077846 1.492842581802114 0.3877020388105745 0.2889748392641485 0.2618628710386065 9.326742826614487 0.08963760795018635 0.10159509770058137 3.987062966603702e-07 6.399346905588522 0.4453920937943294 CDENILWLDYK ddPTM_PC-9_AZD4547_30min_R2 2 CDENILWLDYK 11 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BUW1;H3BTJ2 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ; 189.13 0.0030388999999999998 25489000.0 105776.0 88190.0 128647.0 159386.0 165438.0 140931.0 99192.0 145235.0 120512.0 132600.0 False True 139410.56772252193 116695.6928505548 126941.05672354346 122642.02018915249 142469.78936774767 132118.56229120778 108019.89583963416 122792.26791828586 126882.0182898759 127957.71436029857 1.0895049854514816 0.9119863810787321 0.9920547374432428 0.9584574154225798 1.113413052741678 1.0325173667856653 0.8441843180746083 0.9596316137105415 0.99159334725694 1.0 16.965307602149075 -8.526442748814407 23.159482201314567 1.0000000226436816 0.9846590018809759 0.001151622999019164 0.07499516375416665 1770.5414731737194 11505367.567639358 0.07423729704068091 0.01916798764956296 2.9754814780355554e-09 8.526442748814407 -0.015341020762705715 CDENILWLDYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 CDENILWLDYK 11 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BUW1;H3BTJ2 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ;;; 155.15 0.0016285999999999998 16788000.0 113627.0 114197.0 102806.0 136581.0 139612.0 119113.0 128457.0 124921.0 108385.0 102146.0 False True 132861.80686445252 125533.72345831938 105257.28493392593 128928.8093715765 112256.0308131279 112866.50459354743 116288.62301185721 121641.95611474015 109969.9255807254 120664.26121270908 1.101086647605138 1.0403554639681283 0.8723153307869389 1.0684920959678237 0.9303171434932254 0.9353764193242303 0.9637370820748786 1.0081026054625037 0.9113711423374024 1.0 16.88063891104276 -5.023902268009851 9.213264384657133 0.9628854238771946 1.0862853669073216 0.43077999084205587 0.05241146654584886 0.24922253247154313 95.25114516115674 0.01248003469601036 0.03568599095997184 9.464501229643786e-06 5.023902268009851 0.12339994303012702 CDENILWLDYK ddPTM_PC-9_Lapatinib_30min_R1 4 CDENILWLDYK 11 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BUW1;H3BTJ2 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ;;; 176.42 0.00048131 64330400.0 151086.0 137051.0 159632.0 136969.0 139727.0 123891.0 146736.0 129474.0 128814.0 124999.0 False True 148931.48593422107 136733.66682988862 146507.67315733977 147042.15717518935 131508.53257385167 118592.47073402657 154333.27209523783 135489.83470807533 114305.61084844502 146604.91059930186 1.0158696958062896 0.9326677140004324 0.999336738165423 1.0029824824700624 0.8970267915055631 0.8089256372739216 1.0527155704699347 0.9241834680312581 0.7796847348508212 1.0 17.16157390245567 -6.264620382177262 24.241267120442288 0.9086716615212711 0.9846124545654299 0.1915250425486834 0.07764158973000586 330.08549375376555 2515458.2053978224 0.023876374384051584 0.02823209835079325 5.437253954752394e-07 6.264620382177262 0.0759407930441588 CDEPILSNR ddPTM_PC-9_Lapatinib_30min_R1 1 CDEPILSNR 9 0 P30086 P30086 PEBP1 Phosphatidylethanolamine-binding protein 1;Hippocampal cholinergic neurostimulating peptide 0 120.87 0.007607200000000001 5660200.0 21747.0 29905.0 35100.0 25469.0 31113.0 23268.0 26423.0 33753.0 23209.0 32684.0 False True 21436.883792088636 29835.756809857707 32214.213489918217 27342.075222093357 29282.994510511526 22272.881880357196 27791.053651268063 35321.28760138454 20594.958018395184 38333.38585130752 0.5592222892921795 0.7783230243628488 0.840369635358454 0.7132705503278872 0.7639031580486572 0.5810309051945509 0.7249830150424903 0.9214236315673576 0.5372590383297099 1.0 15.226313811425367 -10.647588710437304 4.094387975904717 1.0000696808675824 0.7230194018994965 0.3439741112496112 0.11809374406803988 20408553.95579658 7581877.524965518 12792.29207991002 0.02759134993713589 2.2511855351226956e-11 10.647588710437304 -0.2770502789680859 CDGDASPPS(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 CDGDASPPSPAR 12 0 E7EUV9;F8W8D3;Q14493 E7EUV9 SLBP Histone RNA hairpin-binding protein 1 CDGDAS(0.006)PPS(0.994)PAR;CDGDASPPS(1)PAR;CDGDAS(0.149)PPS(0.851)PAR 88.163 0.0081846 48022600.0 34914.0 42602.0 44320.0 45232.0 48948.0 37542.8 42734.0 46909.0 41855.0 31703.4 True False 40824.2506170671 46831.24501319047 45376.756884535986 42697.797684122575 39356.99077615805 35573.98947767779 38685.92615263251 45677.6884541939 42467.05019311947 37450.97545602369 1.0900717570094918 1.2504679635963405 1.2116308409061076 1.1400984130375962 1.0508936094968333 0.9498815196269073 1.0329751276587962 1.2196661875424397 1.1339370917851215 1.0 15.192715675462864 -6.05151493768415 3.8674084197295864 1.0688562658094647 1.1897340036597213 0.3224227994842247 0.07856049531912022 0.2994920125532651 9.158799177514073 0.025807392187802605 0.03565740744845152 8.881474277065715e-07 6.05151493768415 0.12087773785025657 CDILVQEELLAS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 CDILVQEELLASPK 14 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 CDILVQEELLAS(1)PK;CDILVQEELLAS(1)PK 121.82 6.676e-05 7908500.0 70965.0 75046.0 53214.0 41282.0 52966.0 71546.0 81855.0 67595.0 69813.0 55559.0 True False 93530.39383630305 99303.15189548404 52508.34759059005 31765.07270054208 45612.58515971017 67072.21730979519 89139.93642585323 57149.74592857453 73503.17265393569 53613.89632084343 1.7445177510805405 1.852190545921544 0.9793794369348311 0.5924783475994599 0.8507604984862368 1.2510229980006058 1.6626274630817752 1.065950245185901 1.3709724101018177 1.0 15.710319364463416 -5.258214878923559 24.964072183843466 1.0979433414599447 1.7983542206151661 0.5077009963248551 0.27638944767861356 239.503309349447 1854211.1392699166 0.08007675663314241 0.19430070173215844 5.518043516224849e-06 5.258214878923559 0.7004108791552215 CDILVQEELLAS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 CDILVQEELLASPK 14 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 CDILVQEELLAS(1)PK;CDILVQEELLAS(1)PK 164.01 0.00010167 4831700.0 44191.7 66683.0 39826.0 48744.0 51269.0 29125.9 58645.0 34347.2 33215.5 34121.7 True False 51672.48198413947 73302.84754740579 40775.60288094608 46013.03171018019 41223.207487595966 27598.486530783422 53089.72104696805 33445.62239386657 33701.213849947664 40307.694102771435 1.2819508318285722 1.8185820146522773 1.011608423369038 1.1415446289947029 1.0227131173142843 0.6846952460345737 1.3171113413634288 0.8297577705286533 0.8360987796528522 1.0 15.29876763230801 -5.312183836955421 10.146022883152186 0.9827581141140949 1.549874792231617 0.5544451902915819 0.20431963071245118 0.3981274524580351 78.54764032139155 0.05157576566737876 0.10770870146860277 4.873221628521537e-06 5.312183836955421 0.5671166781175221 CDILVQEELLAS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 CDILVQEELLASPK 14 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 CDILVQEELLAS(1)PK;CDILVQEELLAS(1)PK 111.7 0.00037465 6769700.0 46003.0 76072.0 54962.0 72538.0 78610.0 63230.0 74293.0 79469.0 57976.0 76828.0 True False 45346.988784083034 75895.85995784967 50443.23651945537 77872.68649967448 73986.31435320634 60525.80029632913 78139.52802155913 83161.41985584763 51446.13236565468 90107.61743312483 0.5032536657373968 0.8422801769692478 0.5598110121698959 0.8642186833701296 0.8210883437032032 0.6717057005890713 0.8671800481191498 0.9229122045932192 0.5709409906863474 1.0 16.459361451941923 -5.710476224079278 0.05117137171017411 1.4335423705084784 5.561899376114083e-15 0.26657855502237215 0.139798024277872 234.04273984592237 2.659401162195018 28.119568025016473 47.344696651566906 1.947707676385194e-06 5.710476224079278 -1.4335423705084729 CDSLLHFTENLFPS(ph)PNKK ddPTM_PC-9_AZD4547_30min_R2 1 CDSLLHFTENLFPSPNKK 18 1 Q56NI9;E5RFP7;E5RIE3;E5RFE4 Q56NI9 ESCO2 N-acetyltransferase ESCO2 1 CDSLLHFTENLFPS(1)PNKK 77.469 0.0018039000000000002 2150400.0 7646.0 5674.3 11549.0 19259.0 16889.0 11606.0 10060.0 14922.0 10310.0 15205.0 True False 10077.268953320254 7508.406508015689 11395.852714017456 14819.135098583873 14544.25387536051 10880.274985288961 10955.320511197679 12616.147773447588 10854.96555171784 14672.677578041805 0.6868050428915069 0.5117270837636542 0.7766716506516687 1.0099816492090883 0.9912474255637236 0.741533024726972 0.7466476689702986 0.8598395014368824 0.7398080884679624 1.0 13.840844548179925 -5.454220492176312 5.592002075235392 0.861178466460265 0.6045578640434944 0.4952959242705931 0.10778399354844971 0.18781944502890713 11.030083185082331 0.02987017815435562 0.06265673215982656 3.5138199789179364e-06 5.454220492176312 -0.25662060241677054 CDST(ph)SSGSSALSR ddPTM_PC-9_Lapatinib_30min_R1 1 CDSTSSGSSALSR 13 0 O75509 O75509 TNFRSF21 Tumor necrosis factor receptor superfamily member 21 1 CDS(0.151)T(0.357)S(0.239)S(0.239)GS(0.012)S(0.002)ALSR 103.46 0.0029877 0.0 9654.6 10497.0 10131.0 5071.4 7045.4 5618.7 6027.2 7275.9 7736.5 4826.4 True False 9516.9236335632 10472.69484143376 9298.06828679092 5444.367673694463 6631.003423789343 5378.4012988294235 6339.258924683905 7613.964875978843 6865.133901043316 5660.636809226247 1.681246113167269 1.8500912873202464 1.6425834407245556 0.9617942039349198 1.1714235778175168 0.9501406785298768 1.1198844120067153 1.3450721416305804 1.2127847329568757 1.0 12.46674864687714 -5.666044880414038 5.330119847522529 1.120580181018108 1.758421630686351 0.8436528377888856 0.12189117558796399 0.07740938925472224 3.45361383796122 0.03504804084601692 0.06145846240334919 2.1575214372686465e-06 5.666044880414038 0.637841449668243 CEDPDS(ph)PVTKK ddPTM_PC-9_AZD4547_30min_R2 1 CEDPDSPVTKK 11 1 Q9BUB4-2;Q9BUB4 Q9BUB4-2 ADAT1 tRNA-specific adenosine deaminase 1 1 CEDPDS(0.735)PVT(0.265)KK 62.924 0.024301 4862900.0 34105.0 31028.0 30361.0 40275.0 39241.0 34242.0 30800.0 41398.0 30615.0 36397.0 True False 44949.680571931385 41057.19421438954 29958.393302475026 30990.220992547165 33793.06449896511 32100.84232692269 33541.14033249386 35000.89033140218 32233.24639823877 35122.752108384586 1.2797881109436435 1.1689629015315195 0.8529625813497481 0.8823403387329977 0.9621417021844924 0.913961475110588 0.9549690248927515 0.9965304035228688 0.9177312272902434 1.0 15.100118273897614 -5.102683144116221 4.190385964847241 0.9346719328206714 1.258922808732472 0.8693964207575815 0.04563254350667398 0.07048824793781705 2.074680255878482 0.012278756323829399 0.038235845407443333 7.894358702112581e-06 5.102683144116221 0.3242508759118006 CEFQDAYVLLSEK ddPTM_PC-9_Lapatinib_30min_R1 3 CEFQDAYVLLSEK 13 0 P10809 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 ;; 222.73 1.4495e-15 13329300.0 63151.0 57822.0 73738.0 59199.0 56544.0 50510.4 67002.0 56498.0 65519.0 51827.9 False True 62250.45515952492 57688.116711573064 67675.54627691137 63552.69194207489 53218.19308978119 48350.187937493276 70471.03571669613 59123.10333608935 58139.56027434336 60786.28345866423 1.0240872054935939 0.9490318116060185 1.1133358123947807 1.0455104067234489 0.8754967413984197 0.7954128001652261 1.1593246322522368 0.9726388910796648 0.9564585456829141 1.0 15.891458193042585 CELLYEGPPDDEAAMGIK ddPTM_PC-9_Lapatinib_30min_R1 1 CELLYEGPPDDEAAMGIK 18 0 P13639 P13639 EEF2 Elongation factor 2 0 118.37 0.00091481 0.0 9499.7 9278.3 10021.0 6925.7 11075.0 6275.2 8354.2 7186.1 7981.5 7298.2 False True 9364.23253596838 9256.816666407058 9197.11206217864 7435.039081457929 10423.590274287759 6006.824324205666 8786.739598585458 7519.992440147827 7082.539421078942 8559.684145759777 1.0939927661474698 1.0814437202093048 1.074468625893705 0.8686113827156853 1.2177540779295353 0.7017577076347233 1.026526148507262 0.8785362067212512 0.8274299963027759 1.0 13.063341846504247 -6.75608947903308 24.99995536782757 0.8879882885489335 1.0574074926291908 0.37683046755511174 0.11564613006910705 150.13986759714936 701600.0094388752 0.037005794631761325 0.0359705972692177 1.7535191816497352e-07 6.75608947903308 0.16941920408025724 CEPCLPYSADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CEPCLPYSADR 11 0 Q5T5P2;Q5T5P2-2;Q5T5P2-7;Q5T5P2-10;Q5T5P1;A0A0U1RQK8 Q5T5P2 KIAA1217 Sickle tail protein homolog 0 102.51 0.015149000000000001 8580900.0 13530.0 18402.0 19808.0 21417.0 25066.0 21624.0 21188.0 14253.0 21884.0 14690.0 False True 15820.361770319018 20228.82894541879 20280.29784225831 20217.074924850833 20154.49723778658 20489.999373123588 19180.91925216404 13878.873852301807 22204.01209953951 17353.180714023983 0.9116692801760419 1.1657130343298303 1.1686789976127416 1.1650356933419355 1.1614295713234124 1.1807633258013952 1.1053258516845255 0.7997884699653699 1.2795355771057766 1.0 14.08291250228244 -7.543176652370139 24.9997459924161 1.0143086631489475 1.1336173996550571 0.09924941365860929 0.13117650117053245 462.3437392409781 569434.9176269307 0.05826449605499104 0.03364375696966417 2.8630131820501362e-08 7.543176652370139 0.11930873650610962 CEQDRPSPTTAPPAPPSPS(ph)PSPVPK ddPTM_PC-9_Lapatinib_30min_R1 1 CEQDRPSPTTAPPAPPSPSPSPVPK 25 1 P11279-2;P11279 P11279-2 LAMP1 Lysosome-associated membrane glycoprotein 1 1 CEQDRPSPTTAPPAPPS(0.142)PS(0.429)PS(0.429)PVPK 49.662 0.012963999999999998 7281400.0 17247.0 14861.0 11867.0 16201.0 12023.0 15414.0 13535.0 13629.0 13306.0 10477.0 True False 17001.054617287566 14826.590267557118 10891.341067944708 17392.475584951695 11315.830778127467 14754.779151788973 14235.776072736366 14262.253095110653 11807.33816160827 12287.935490275022 1.3835566300573945 1.2065973392594103 0.8863442582819862 1.4154107171799961 0.9208895006881422 1.2007533050174517 1.1585165045831265 1.160671221491857 0.9608886839414881 1.0 13.584954926819414 -4.891673652955052 4.095145761419118 1.1027307352527684 1.3800071006855332 0.2644699795531047 0.1502609792678146 0.2929495777074355 8.242675005995784 0.03518320955882921 0.1849749101389155 1.2832945416438174e-05 4.891673652955052 0.2772763654327648 CFIVGADNVGSK ddPTM_PC-9_Lapatinib_30min_R1 2 CFIVGADNVGSK 12 0 F8VWV4;F8VS58;F8VQY6;F8VPE8;F8VRK7;G3V210;F8VZS0;F8VU65;F8VWS0;P05388-2;Q8NHW5;P05388 F8VWV4 RPLP0;RPLP0P6 60S acidic ribosomal protein P0;60S acidic ribosomal protein P0-like 0 ; 154.66 0.00029298 9100800.0 156670.0 148066.0 164678.0 161843.0 178486.0 148741.0 191809.0 144483.0 145210.0 165396.0 False True 154435.85707024042 147723.16227414773 151138.8105154629 173745.4741124208 167987.80439697727 142379.6941622062 201739.93149135512 151196.20764112362 128854.92067091064 193984.4782236834 0.7961248161935952 0.7615205279662027 0.7791283709884499 0.8956668889356961 0.8659858043037373 0.7339746739841125 1.0399797619824453 0.7794242561344488 0.6642537683985628 1.0 17.56558169341831 -5.698148736913081 11.942816664033197 0.8482055199366418 0.777064531808341 0.09215206031463496 0.10705804978677211 1.934886758178566 358.78331597808364 0.028805337705120566 0.049890419150363303 2.0037856545312256e-06 5.698148736913081 -0.07114098812830083 CFSIDNPGYEPEVVAVHPGGDTVAIGGVDGNVR ddPTM_PC-9_Lapatinib_30min_R1 1 CFSIDNPGYEPEVVAVHPGGDTVAIGGVDGNVR 33 0 O75083;O75083-3 O75083 WDR1 WD repeat-containing protein 1 0 118.67 1.4438999999999998e-10 0.0 4882.2 5267.1 6478.0 4113.5 5837.8 5255.6 5096.2 5427.8 5865.2 4951.1 False True 4812.578932714172 5254.904353559659 5945.403845803135 4416.020512233734 5494.432081556398 5030.83023940198 5360.056300101893 5679.995403158093 5204.599412705909 5806.891038073937 0.8287703180858093 0.9049428203672022 1.0238531783739375 0.7604793138495785 0.9461916963020581 0.8663551987485949 0.9230509518704086 0.9781474055421687 0.896279847267842 1.0 12.503550247873479 -8.765691879408942 0.37810087862182806 1.0085259659752452 0.8850346167416234 0.18095739305654635 0.06903116630320308 3.453754390378213 1.1544366340051109 0.13851404774589046 0.05942522556982105 1.7151737469141857e-09 8.765691879408942 -0.12349134923362182 CGDLVFAK ddPTM_PC-9_Lapatinib_30min_R1 1 CGDLVFAK 8 0 P51858 P51858 HDGF Hepatoma-derived growth factor 0 96.25299999999999 0.028458999999999998 2116200.0 42769.0 33459.0 37039.0 30946.0 34688.0 33305.0 33488.0 30500.0 32819.0 32615.0 False True 42159.10621712597 33381.52774121482 33993.79639467465 33221.872072829734 32647.720039231925 31880.622787746972 35221.84478195755 31917.141345724194 29122.578620608878 38252.45929324425 1.1021279937567745 0.8726635713879531 0.888669565898428 0.868489835337124 0.8534802896972908 0.8334267489404896 0.9207733419685795 0.8343814211014943 0.7613256548384121 1.0 15.223264882808657 -4.760634765057857 6.011852114722623 0.8650376671069375 1.1109696607546813 0.5810167307966285 0.05892470245338496 0.09069159717486763 12.662389975348452 0.013933411015144077 0.09190506739094088 1.7352627133925553e-05 4.760634765057857 0.24593199364774376 CGEDDETIPSEYR ddPTM_PC-9_Lapatinib_30min_R1 1 CGEDDETIPSEYR 13 0 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;F8W7E0;E9PDE4;P20810-2;E9PCH5;P20810-3;H0Y7F0;H0Y9H6;E7EQ12;E7EQA0;H0YD33;A0A0A0MR45;D6RAA8 P20810-6 CAST Calpastatin 0 120.86 0.00094989 2769800.0 10658.0 11231.0 13535.0 8870.6 15553.0 12678.0 10525.0 10923.0 14195.0 13217.0 False True 10506.014965562179 11204.995309530577 12422.204546610901 9522.973515454132 14638.20311837449 12135.791493861465 11069.933000779482 11430.522456371982 12596.209620023263 15501.540839454517 0.6777400436750308 0.7228310672840745 0.8013528897071902 0.6143243187294171 0.9443063286403981 0.7828764649623379 0.7141182360791059 0.7373797595190679 0.8125779076079581 1.0 13.920124004788057 -14.522878745278765 0.21150247592297858 2.1699558472747817 0.723628178265629 0.4603381238073194 0.0818849605840796 139.2619585216332 1.385478904091317 69.17340193010025 0.17264484985904127 3.0000000000108605e-15 14.522878745278765 -1.4463276690091527 CGEEGHLS(ph)PYCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CGEEGHLSPYCR 12 0 Q9NUD5-2;Q9NUD5 Q9NUD5-2 ZCCHC3 Zinc finger CCHC domain-containing protein 3 1 CGEEGHLS(0.997)PY(0.003)CR 55.815 0.044853 2476200.0 33632.0 35091.0 29926.0 32787.0 32999.0 34588.0 38057.0 28232.0 32326.0 25170.0 True False 39325.23333772127 38574.60257166017 30639.54933498701 30950.050686888197 26533.082835303576 32774.144391305934 34451.965451180215 27490.939914276594 32798.70659521633 29733.121754389627 1.3226069452971423 1.2973613363004926 1.0304854494622167 1.040928394352635 0.892374606826691 1.102277273877821 1.1587066348354063 0.9245897602466848 1.103103362847331 1.0 14.85978332288714 -5.250100195888141 5.588544828225724 1.0307493099793021 1.3140807022110397 0.680233377951914 0.07639999530512628 0.09028383323417341 10.598099341041225 0.019933593099740517 0.04993210904410456 5.6221160263622915e-06 5.250100195888141 0.28333139223173753 CGEEGHLS(ph)PYCR ddPTM_PC-9_Lapatinib_30min_R1 1 CGEEGHLSPYCR 12 0 Q9NUD5-2;Q9NUD5 Q9NUD5-2 ZCCHC3 Zinc finger CCHC domain-containing protein 3 1 CGEEGHLS(0.992)PY(0.008)CR 88.507 0.0045323 3084700.0 25588.0 28516.0 30463.0 25465.0 28301.0 29307.0 28956.0 23903.0 28386.0 19320.0 True False 25223.1104277355 28449.97295401781 27958.44973058056 27337.78104874974 26636.390821906818 28053.607927953773 30455.199997203854 25013.620642191658 25188.869762168386 22659.43625771819 1.1131393623768588 1.2555463706352035 1.2338546031151785 1.2064634237949334 1.1755098634827692 1.238054098472915 1.344040498219822 1.1038942168595034 1.1116282627547112 1.0 14.467824348461129 -7.952846479791909 12.477760713613304 1.0731068965578856 1.2235139179986692 0.5687930673022297 0.061218792386994195 0.6787109312518526 178.51289065460196 0.03332376789219347 0.015998454822338137 1.1146884989190334e-08 7.952846479791909 0.15040702144078355 CGENT(ph)SPVLDAVLK ddPTM_PC-9_AZD4547_30min_R2 2 CGENTSPVLDAVLK 14 0 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 CGENT(0.76)S(0.24)PVLDAVLK;CGENT(0.86)S(0.14)PVLDAVLK 97.273 0.0067058000000000005 4092500.0 36079.0 32753.0 40931.0 50610.0 53279.0 45768.0 35661.0 45592.0 37136.0 39327.0 True False 47551.37151018067 43339.76673017599 40388.2281961597 38942.646416705444 45882.13051248345 42906.11972485831 38834.7599154891 38546.80399993448 39098.933145353396 37950.17370020717 1.2529948317448962 1.1420176116332084 1.0642435661879255 1.0261519940419366 1.2090097630365517 1.130590865375251 1.0233091479967877 1.015721411565609 1.030270202561417 1.0 15.211818868506501 -1.5228787452803376 0.20204480622126114 0.9974466078580073 1.9855255720139733 0.5007014751286288 0.059729889508732356 52.9955283849533 0.6443855619408301 0.120440598157588 16.62707488259457 0.029999999999999995 1.5228787452803376 0.988078964155966 CGENT(ph)SPVLDAVLK ddPTM_PC-9_Lapatinib_30min_R1 1 CGENTSPVLDAVLK 14 0 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 CGENT(0.5)S(0.5)PVLDAVLK 105.63 0.0023301 1737000.0 9306.8 8212.4 8457.5 9608.0 11137.0 10207.0 7952.8 8996.2 11436.0 7612.6 True False 9174.083325341908 8193.384692368352 7762.156996894108 10314.604371348427 10481.943556184453 9770.470403679128 8364.55707065074 9414.196294242753 10147.957253581266 8928.427766848115 1.027513865252506 0.9176738510212257 0.8693755720033427 1.1552542777629096 1.173996568030113 1.0943102927883426 0.9368454658623026 1.0544069504821811 1.136589500254608 1.0 13.124190433953569 -5.759319029925768 24.99999705958845 1.0797403519954256 0.9361363709018169 0.41450677642343303 0.07654914062428443 57.788766992093 681337.9653571198 0.022690366129174126 0.03694300049743782 1.740527823143373e-06 5.759319029925768 -0.14360398109360872 CGENTS(ph)PVLDAVLK ddPTM_PC-9_Lapatinib_30min_R1 1 CGENTSPVLDAVLK 14 0 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 CGENT(0.111)S(0.889)PVLDAVLK 102.29 0.0014971 1293900.0 11590.0 11298.0 11977.0 12382.0 11847.0 13604.0 12745.0 9996.8 12582.0 10470.0 True False 11424.724474654304 11271.840175147054 10992.297292556987 13292.613585141147 11150.18275209816 13022.188632472891 13404.873738236065 10461.287823112634 11164.882665666259 12279.725549601937 0.9303729491759407 0.9179228093996323 0.8951582222383884 1.0824845825297817 0.9080156317060041 1.0604625144000082 1.091626493123912 0.8519154423163594 0.9092127198256628 1.0 13.583990696556164 -3.1599699945617106 18.97560677729392 0.9652527721116853 0.921607297500081 0.0 0.08223003160426216 0.0 0.0 0.019319760358643693 0.0 0.0006918787712237894 3.1599699945617106 -0.043645474611604285 CGESGHLAR ddPTM_PC-9_AZD4547_30min_R2 2 CGESGHLAR 9 0 P62633-8;P62633-4;P62633-5;P62633-6;P62633-2;P62633;P62633-7;P62633-3 P62633-8;P62633-2 CNBP Cellular nucleic acid-binding protein 0 ; 159.28 0.00010567 9554200.0 24231.0 20109.4 57058.0 92819.0 76941.0 70783.0 55383.0 80083.0 57446.0 70763.0 False True 31935.95396388999 26609.370289249873 56301.37363896507 71421.01358925473 66259.07024833412 66356.92782041265 60311.97970891261 67708.01247426635 60482.47828166659 68285.60890858095 0.4676820559167165 0.3896775721056222 0.8244983758487082 1.0459160389837245 0.9703226098055314 0.9717556726959794 0.88323119135771 0.9915414617582472 0.8857280362343843 1.0 16.059293944245702 -5.368761701713044 3.6348640342107545 0.9598417885870069 0.42553537034607897 0.9410503784345401 0.052683188559627676 0.046473551709860346 1.1075200530560119 0.013872535239635865 0.032362800641235534 4.277975551737325e-06 5.368761701713044 -0.5343064182409278 down CGESGHLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 CGESGHLAR 9 0 P62633-8;P62633-4;P62633-5;P62633-6;P62633-2;P62633;P62633-7;P62633-3 P62633-8;P62633-2 CNBP Cellular nucleic acid-binding protein 0 ; 112.11 0.0018382000000000001 7031200.0 27554.8 41858.0 60519.0 79844.0 92166.0 78568.0 71317.0 61576.0 70955.0 53026.0 False True 32219.283407892555 46013.38561011523 61962.00247958559 75370.59953774072 74106.73391916706 74447.75576894073 64561.33746963299 59959.69524516494 71992.58264132828 62639.19404641495 0.5143629942623211 0.7345781871972972 0.9891890121330813 1.2032498292026546 1.1830729154058846 1.18851714014353 1.030685953937941 0.9572232873995069 1.149321662535801 1.0 15.934778029714792 -5.13457034296206 2.004623663282805 1.1040376031731143 0.5069943046612665 0.8474109780923266 0.08208680485563177 0.15739226055002165 1.0676491521875122 0.02490674680067473 0.13150569574737805 7.3354989123871286e-06 5.13457034296206 -0.5970432985118478 CGESGHLAR ddPTM_PC-9_Lapatinib_30min_R1 2 CGESGHLAR 9 0 P62633-8;P62633-4;P62633-5;P62633-6;P62633-2;P62633;P62633-7;P62633-3 P62633-8;P62633-2 CNBP Cellular nucleic acid-binding protein 0 ; 113.62 0.0017532 7226500.0 59244.0 48021.0 74508.0 54255.0 77926.0 80670.0 60277.0 65796.0 85623.0 52769.0 False True 58399.169695980985 47909.81032490146 68382.23984919736 58245.09368937431 73342.54588841065 77219.93215095479 63397.84812237384 68853.12236010721 75979.23608983806 61890.05133972726 0.9435954314436725 0.7741116591084184 1.104898741702978 0.9411059197487974 1.1850458078604311 1.2476953965844793 1.0243625065742792 1.1125071133348754 1.227648619529694 1.0 15.917419898256018 -5.605514695127409 1.3300912007817893 1.1319508474464441 0.8590245416365052 0.4428714599268866 0.10499759752649925 0.43006877606997823 1.441096304027506 0.03381120929228448 0.10526046348406749 2.4801920145583125e-06 5.605514695127409 -0.27292630580993893 CGGSS(ph)S(ph)EES(ph)KY(ph)SWQREK ddPTM_PC-9_Lapatinib_30min_R1 1 CGGSSSEESKYSWQREK 17 2 E9PQ38 E9PQ38 KBTBD4 4 CGGS(0.074)S(0.951)S(0.951)EES(0.923)KY(0.555)S(0.547)WQREK 49.528 0.039786 4778400.0 3595.3 6589.3 4150.3 4089.9 6541.5 5148.9 6675.3 6471.4 3222.1 6584.0 True False 3544.0303627027274 6574.042880695385 3809.0783546212956 4390.684889506445 6156.741831083825 4928.69354967213 7020.914371506254 6772.0848690072 2859.193167782806 7722.035627371459 0.4589502734409291 0.8513354765410679 0.4932738643576922 0.5685916384461194 0.7972951859041795 0.6382635081612323 0.9092051254749438 0.8769818213481078 0.37026417718770105 1.0 12.91476549515962 -6.261103127530112 24.900716416343826 0.760023996726418 0.6043616479379836 0.16488084587266338 0.18905307064958646 59.956342579233535 4439969.180575316 0.05545428208183392 0.06723146384448542 5.481467865768631e-07 6.261103127530112 -0.15566234878843432 CGGVEQASSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 CGGVEQASSSPR 12 0 Q5VZL5-2;Q5VZL5-4;Q5VZL5;H7C1I7;Q5VZL5-3 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 CGGVEQAS(0.014)S(0.108)S(0.878)PR;CGGVEQAS(0.01)S(0.088)S(0.902)PR;CGGVEQAS(0.002)S(0.026)S(0.972)PR;CGGVEQAS(0.002)S(0.062)S(0.936)PR 123.28 0.00036229 89204000.0 103266.0 104933.0 122862.0 150319.0 135221.0 129163.0 124120.0 149891.0 109070.0 117662.0 True False 136102.43993376542 138850.54017334463 121232.7696033952 115665.276955399 116447.89823436119 121086.41719152813 135166.43954769944 126728.79010252209 114835.21752918171 113542.6891935254 1.1986895933192894 1.2228928270025718 1.0677285386183042 1.0186941825752938 1.025586931765233 1.066439574855806 1.1904459944340222 1.1161334208539129 1.0113836332822213 1.0 16.792875290972162 -5.2643790144647085 24.36224639364205 1.0680905994291066 1.2107912223354889 0.5419312057413381 0.054473194705708085 136.35952548283032 1130099.4451963517 0.015365274376144244 0.03440247261660641 5.440276655619524e-06 5.2643790144647085 0.1427006229063823 CGGVEQASSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 CGGVEQASSSPR 12 0 Q5VZL5-2;Q5VZL5-4;Q5VZL5;H7C1I7;Q5VZL5-3 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 CGGVEQAS(0.004)S(0.075)S(0.921)PR;CGGVEQAS(0.004)S(0.033)S(0.963)PR;CGGVEQASS(0.001)S(0.999)PR 135.04 5.9204e-05 58611000.0 114758.0 113705.0 109501.0 135538.0 143560.0 112897.0 128237.0 119580.0 105224.0 93377.0 True False 134184.26282618413 124992.88094983416 112111.91912485525 127944.24528012484 115430.44855408314 106976.48257619026 116089.4630045193 116441.15170548279 106762.70193574982 110305.51092807486 1.2164783218644397 1.1331517337455266 1.0163764093161063 1.159908006441776 1.0464613017326942 0.9698199271833725 1.0524357489284093 1.0556240638004812 0.9678818495783484 1.0 16.751145345057793 -1.5228787452854178 0.3807989887001699 1.0082502100312303 3.882263470026112 0.6214456374172175 0.04851113197860799 47.90714051610774 0.653317479808485 0.03791318066051485 101.66974804067678 0.02999999999964907 1.5228787452854178 2.8740132599948813 CGGVEQASSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 CGGVEQASSSPR 12 0 Q5VZL5-2;Q5VZL5-4;Q5VZL5;H7C1I7;Q5VZL5-3 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 CGGVEQAS(0.004)S(0.107)S(0.889)PR;CGGVEQAS(0.001)S(0.005)S(0.994)PR 119.21 0.00054913 41129000.0 51613.0 57327.0 61768.0 54975.0 53247.0 56477.0 57207.0 57298.0 65026.0 46974.0 True False 50876.98915533502 57194.26285366039 56689.67347137512 59018.04489122391 50115.11614762981 54061.61036431726 60168.89854399925 59960.27425663293 57702.087125863465 55093.393311079395 0.9234680620970854 1.0381328761276083 1.0289740759165529 1.0712363378669445 0.9096393076509149 0.9812721111415978 1.0921254787168675 1.0883387399660278 1.047350392814876 1.0 15.749591703630546 -7.254566972711815 24.915913675347404 1.0643152149830526 0.9957341308653016 0.2645679887677056 0.05217449413495932 705.5924822352447 2558136.3093196503 0.020770778930724796 0.015707228117969974 5.564588159226859e-08 7.254566972711815 -0.06858108411775099 CGHTNNLRPK ddPTM_PC-9_Lapatinib_30min_R1 1 CGHTNNLRPK 10 1 P62987;M0R2S1 P62987 UBA52 Ubiquitin-60S ribosomal protein L40;Ubiquitin;60S ribosomal protein L40 0 58.433 0.034662 3645200.0 26831.0 27841.0 28516.0 28519.0 23662.0 22985.0 22714.0 29917.0 25711.0 21881.0 False True 26448.385019797202 27776.535875045935 26171.524554943222 30616.3823965951 22270.247681281882 22001.98513065197 23890.019779544447 31307.05303737803 22815.156431167165 25663.101695400204 1.0305997043427433 1.0823530298375639 1.019811434548231 1.1930117707511056 0.8677925196108914 0.857339280021462 0.930909290042148 1.2199247545743637 0.8890256798248397 1.0 14.64740792761323 -6.267251505620359 24.979252501022835 0.9651574000063721 1.0771065907123718 0.23490896754062573 0.10634906029085811 822.6327306068383 3535487.6006235685 0.03425257247742042 0.03985549681323394 5.404412556968971e-07 6.267251505620359 0.11194919070599973 CGSGPVHISGQHLVAVEEDAES(ph)EDEEEEDVK ddPTM_PC-9_AZD4547_30min_R2 3 CGSGPVHISGQHLVAVEEDAESEDEEEEDVK 31 0 P06748;P06748-3;P06748-2;E5RI98 P06748;E5RI98 NPM1 Nucleophosmin 1 CGSGPVHISGQHLVAVEEDAES(1)EDEEEEDVK;CGSGPVHISGQHLVAVEEDAES(1)EDEEEEDVK;CGSGPVHISGQHLVAVEEDAES(1)EDEEEEDVK 89.08 3.7517e-09 41157300.0 57187.5 54858.4 121446.0 223086.0 145616.0 153124.0 90674.0 175404.0 93766.0 138157.0 True False 75371.93542610537 72590.30498551847 119835.54668859334 171656.969344342 125399.73191512215 143549.13207370188 98743.81034118688 148299.34218293775 98722.27933291694 133320.16548171823 0.56534534857325 0.5444810597349021 0.898855370120479 1.2875544275249253 0.9405908810720597 1.0767248266983762 0.7406517234988529 1.1123549213061363 0.740490224987415 1.0 17.02453548772298 -5.3195883987853145 4.405535494445055 0.9883391607597786 0.5512824484960142 0.5431875630450937 0.15508917512097883 0.14316883952502477 5.746077957933877 0.04000280651941083 0.09160306299152426 4.790839274976162e-06 5.3195883987853145 -0.4370567122637644 CGSGPVHISGQHLVAVEEDAES(ph)EDEEEEDVK ddPTM_PC-9_Lapatinib_30min_R1 3 CGSGPVHISGQHLVAVEEDAESEDEEEEDVK 31 0 P06748;P06748-3;P06748-2;E5RI98 P06748;E5RI98 NPM1 Nucleophosmin 1 CGSGPVHISGQHLVAVEEDAES(1)EDEEEEDVK;CGSGPVHISGQHLVAVEEDAES(1)EDEEEEDVK;CGSGPVHISGQHLVAVEEDAES(1)EDEEEEDVK 94.949 2.0962e-12 69329600.0 87526.4 91433.0 183747.0 109937.0 158986.0 186596.0 136909.0 145464.0 188455.0 131423.0 True False 86278.2574856241 91221.2925061268 168640.0309439315 118022.13371908125 149634.75605850216 178615.72405652085 143997.47811911802 152222.7884824404 167229.21338087245 154139.29043985988 0.5597421477639867 0.5918107722295398 1.094075562841191 0.7656849423809281 0.9707762091774047 1.158794253864889 0.9342035876005356 0.9875664280538048 1.0849226884570344 1.0 17.233875129265975 -5.251103776462674 24.22812417234691 0.9930391570345412 0.5757763285627604 0.7370536576305617 0.10117584005801553 230.36145335207854 539995.5933495878 0.026154215169169027 0.06747691905379417 5.609139273145126e-06 5.251103776462674 -0.41726282847178076 CGSGPVHISGQHLVAVEEDAES(ph)EDEEEEDVKLLSISGK ddPTM_PC-9_AZD4547_30min_R2 1 CGSGPVHISGQHLVAVEEDAESEDEEEEDVKLLSISGK 38 1 P06748;P06748-3;P06748-2;E5RI98 P06748;E5RI98 NPM1 Nucleophosmin 1 CGSGPVHISGQHLVAVEEDAES(0.99)EDEEEEDVKLLS(0.008)IS(0.001)GK 53.482 0.00026095 5942100.0 5103.8 4104.5 15699.0 36373.0 19570.0 13491.0 9603.8 14716.0 6671.2 13993.0 True False 6726.7022343651415 5431.199357127819 15490.821002455632 27987.766807248103 16853.043302789098 12647.405637302549 10458.519594974181 12441.98034003852 7023.826012475268 13503.109329137715 0.49815950314864976 0.40221842427122273 1.1472039976028876 2.072690528162624 1.2480861179449032 0.936629136965611 0.774526765654355 0.9214159521904015 0.5201636038981695 1.0 13.721004031063996 -6.994922097678252 5.5100451761245965 0.8036343626620605 1.0967275909583232 0.07523854949413444 0.4418761980720734 0.516862051074115 53.062524461570106 0.18533457659364375 0.1554823355339259 1.011760924344513e-07 6.994922097678252 0.2930932282962627 CHELSPR ddPTM_PC-9_AZD4547_30min_R2 2 CHELSPR 7 0 Q9UGI8-2;Q9UGI8 Q9UGI8-2 TES Testin 0 ; 155.51 0.00039543 4331200.0 7809.8 5067.2699999999995 9224.8 16149.6 12479.0 15363.3 8679.1 12651.0 8231.5 11984.0 False True 10293.153946068593 6705.165931634319 9102.47312462275 12426.55922883276 10746.506253219484 14402.630422323782 9451.523086355446 10696.078641059212 8666.60028505969 11564.443807645705 0.8900690873921137 0.5798087692899915 0.7871085956252172 1.0745488010947035 0.9292713451653032 1.2454235293876945 0.8172916262610638 0.9249107712372313 0.7494178214891635 1.0 13.497408260720515 -5.598407284467193 6.407351758193641 0.9632969205255002 0.7224991769033824 0.30871403902762284 0.14547584161340166 0.2271363853806892 15.110642931097706 0.03951241899926105 0.06920220595528004 2.52111534351896e-06 5.598407284467193 -0.2407977436221178 CHSSQPGMLLDSWS(ph)RMVK ddPTM_PC-9_Lapatinib_30min_R1 1 CHSSQPGMLLDSWSRMVK 18 1 O95714;A0A3B3IRP6;A0A0J9YVP0 O95714 HERC2 E3 ubiquitin-protein ligase HERC2 1 CHSSQPGMLLDS(0.01)WS(0.99)RMVK 54.857 0.019478 7006900.0 41692.0 32128.0 50784.0 34445.0 38508.0 51211.0 37601.0 44865.0 54894.0 28940.0 True False 41097.46443462359 32053.609589938435 46608.73555190901 36978.200205151596 36243.03514964092 49020.82490867168 39547.795796894025 46949.59168773497 48711.25966055345 33942.24043987392 1.2108058838197377 0.9443575077702648 1.3731779325078088 1.089444884189529 1.0677855875142561 1.4442424622943884 1.165149833492869 1.3832201728375169 1.4351221083016517 1.0 15.05079417615708 -6.7448920836865165 24.999996812817482 1.3019733959706774 1.1368719813718515 0.17133585435358822 0.16120471922938656 390.90684596272615 590588.9434047042 0.05082819392167065 0.050686765125226144 1.799317965797665e-07 6.7448920836865165 -0.16510141459882588 CHTPPLYR ddPTM_PC-9_AZD4547_30min_R2 1 CHTPPLYR 8 0 M0R117;Q02543 M0R117 RPL18A 60S ribosomal protein L18a 0 75.854 0.021639 1705200.0 8613.2 5448.5 5393.8 10586.0 10323.0 6007.8 7999.8 10275.0 5258.5 7775.1 False True 11352.018434310485 7209.621073775349 5322.2746877536865 8145.56125206963 8889.829637950537 5632.131316269087 8711.766702333905 8687.234846010851 5536.453574559482 7502.896115556253 1.5130182078322518 0.9609117549724783 0.7093627055182946 1.0856556090628653 1.1848530888650668 0.7506609753787761 1.1611205284145172 1.1578508768099602 0.7379088673612827 1.0 12.873231867610992 -4.760326758615657 24.871560990838507 0.9779523738076781 1.5130188891310647 0.4651339134347019 0.1739313405275499 23.936250023633416 534813.7808756327 0.043016146744153674 0.25678750286516105 1.7364938173749494e-05 4.760326758615657 0.5350665153233867 CIACQAAKLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 CIACQAAKLSPR 12 1 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 CIACQAAKLS(1)PR;CIACQAAKLS(1)PR 93.649 0.025111 46216000.0 21768.0 12345.400000000001 25475.0 55088.0 46458.0 29177.0 23068.1 32369.0 17665.2 30792.0 True False 28689.771197472564 16335.809122544957 25137.184854930707 42388.31270111579 40008.10862345304 27352.55757761296 25121.11621116888 27367.114815622903 18598.946407779436 29713.981452355383 0.9655310327050893 0.5497684364089163 0.8459716142461993 1.4265443615855704 1.3464405195111158 0.9205281904571143 0.8454308370438041 0.9210181025220218 0.625932490319473 1.0 14.858854308072605 -10.647449096790952 4.416977921072343 1.0000072063517271 0.946976435768399 0.004087149914340116 0.25935139478228364 2.02891430383933e-05 4.0210255252048425e-06 0.276827846821231 0.06713149194593014 2.251909345252576e-11 10.647449096790952 -0.05303077058332817 CIACQAAKLS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 CIACQAAKLSPR 12 1 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 CIACQAAKLS(1)PR 96.23 0.020988999999999997 12229000.0 18273.0 7192.1 11427.0 8890.5 9518.5 8444.1 6144.4 1894.7 11350.0 5525.6 True False 18012.42366914221 7175.447134331311 10487.516169495586 9544.33702783859 8958.640544091013 8082.965527158511 6462.526967219902 1982.7346789424137 10071.643479201404 6480.692597600805 2.7793979420981216 1.1072037480974963 1.6182708887284876 1.472734107365618 1.3823585070841904 1.2472379156127351 0.9971969615735781 0.3059448738050675 1.5540998631735738 1.0 12.661932288162268 -3.058430759359022 1.4286542662672779 1.1584000952339615 199.99999999999986 0.6112097942770276 0.37304216236284704 126.52861281980857 2.7016383255949448 0.11026691021593013 80380.86652340904 0.0008741163440075457 3.058430759359022 198.8415999047659 CIFMSETQS(ph)SPTK ddPTM_PC-9_AZD4547_30min_R2 1 CIFMSETQSSPTK 13 0 B4DGW0;A0A087WUY7;O75928-2;O75928 B4DGW0 PIAS2 E3 SUMO-protein ligase PIAS2 1 CIFMSETQS(0.722)S(0.278)PTK 151.66 0.00011887 8563500.0 39820.0 41184.0 41614.0 39946.0 42013.0 45493.0 46999.0 42977.0 38940.0 35559.0 True False 52481.931692546765 54495.922602985 41062.17116989541 30737.06685954781 36180.22014716805 42648.31551833111 51181.819950872734 36335.892163212535 40998.2889024144 34314.09023331723 1.5294571802923538 1.5881500057976838 1.1966562683345205 0.8957564268949695 1.0543837794084632 1.2428805551406337 1.4915686122774663 1.0589204585098468 1.1947945763285066 1.0 15.066513484681748 -5.29795958690965 5.509626976838886 1.1462063142423324 1.5605142782853596 0.5436916988328616 0.15305604951776966 0.14180907132324785 12.111549440874057 0.04340280307771721 0.09669197701029932 5.035474640052962e-06 5.29795958690965 0.41430796404302717 CIFMSETQSS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 CIFMSETQSSPTK 13 0 B4DGW0;A0A087WUY7;O75928-2;O75928 B4DGW0 PIAS2 E3 SUMO-protein ligase PIAS2 1 CIFMSETQS(0.23)S(0.769)PTK;CIFMSETQS(0.05)S(0.95)PTK;CIFMSETQS(0.207)S(0.792)PT(0.001)K 157.5 9.012e-07 15476900.0 175233.0 199262.0 176086.0 185720.0 200932.0 153886.0 195296.0 172196.0 153534.0 145871.0 True False 204896.48589048896 219043.41448331936 180284.55804987377 175314.71051236422 161560.81700243117 145815.94725917952 176796.14905940302 167676.03745674362 155779.14429220866 172316.2575857994 1.1890722834928518 1.2711709130187767 1.0462423022395713 1.0174008707511062 0.9375831350212971 0.8462112008588343 1.025998077815571 0.9730714896315263 0.9040304523480228 1.0 17.394699296904655 -5.502131702386122 1.9413688116486458 0.9496301603602783 1.236766356495465 0.7870220477980909 0.05565533203431872 0.14945626244441548 1.0919119909597337 0.01637856631576968 0.044751317390235947 3.146793885418229e-06 5.502131702386122 0.2871361961351867 CIFMSETQSS(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 3 CIFMSETQSSPTK 13 0 B4DGW0;A0A087WUY7;O75928-2;O75928 B4DGW0 PIAS2 E3 SUMO-protein ligase PIAS2 1 CIFMSET(0.001)QS(0.071)S(0.833)PT(0.096)K;CIFMSETQS(0.035)S(0.965)PTK;CIFMSETQS(0.235)S(0.609)PT(0.157)K 169.58 1.928e-18 12932000.0 65532.0 109785.0 91263.0 96401.0 106445.0 105890.0 102615.0 114764.0 94976.0 87584.0 True False 64597.501662903 109530.79957767055 83759.70842536761 103490.65112430876 100184.11437892183 101361.3315416461 107927.90260094883 120096.3544065802 84278.8027383817 102722.7777016557 0.6288527540650978 1.0662756793414196 0.815395672697211 1.0074752011173533 0.9752862667897566 0.9867464043470112 1.0506715746570903 1.1691307136902362 0.8204490242968117 1.0 16.648396594102948 -4.753985223001934 24.999542869849087 0.9899686741092422 0.6288521162570755 0.5334715120791489 0.1007235738001716 207.47764922765947 695774.7609502678 0.02443154573958336 0.24899872283031843 1.7620359991871603e-05 4.753985223001934 -0.3611165578521667 CIIPNHEK ddPTM_PC-9_AZD4547_30min_R2 1 CIIPNHEK 8 0 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580;P35749-4;P35749-3;P35749;P35749-2 P35579;P35749-4 MYH9;MYH10;MYH11 Myosin-9;Myosin-10;Myosin-11 0 99.13600000000001 0.0044418 5617200.0 58423.0 61517.0 65654.0 80477.0 64974.0 82840.0 74954.0 83193.0 55952.0 61624.0 False True 77000.29872610903 81401.1672194986 64783.38506243847 61924.27100725554 55953.48163287782 77660.00170440612 81624.76079486182 70337.43343495666 58909.508491728055 59466.562516885766 1.2948503405463279 1.3688561062594533 1.0894086074681544 1.0413292510336696 0.9409234242687158 1.305944019924714 1.3726160944931725 1.1828064454706637 0.9906324831706973 1.0 15.85979106223894 -5.260979866410645 24.997173362126844 1.1290928625401802 1.3318532350287309 0.29355512985091126 0.13293786293629556 56.05337356132334 3049030.643474824 0.03775415781285084 0.08828817488472095 5.483023832478264e-06 5.260979866410645 0.20276037248855072 CIIPNHEK ddPTM_PC-9_Lapatinib_30min_R1 1 CIIPNHEK 8 0 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580;P35749-4;P35749-3;P35749;P35749-2 P35579;P35749-4 MYH9;MYH10;MYH11 Myosin-9;Myosin-10;Myosin-11 0 74.301 0.023483 6442700.0 90920.0 81732.0 97875.0 90606.0 91502.0 106110.0 99292.0 83435.0 81024.0 93607.0 False True 89623.46412731381 81542.75457559913 89828.09530842566 97269.46749275544 86120.03225985361 101571.92265449115 104432.8539205127 87311.69469444243 71898.22389945497 109786.84522651289 0.8163406457522496 0.7427370228861174 0.8182045410184781 0.8859847215034596 0.7844294285182368 0.9251738898674731 0.9512328522150919 0.7952837565766683 0.6548892424325894 1.0 16.74434567392173 -5.517823817274111 11.16979235950002 0.8519830623836222 0.7797465352433155 0.09800426576861943 0.093597908734323 0.5071384389913206 1009.0543920039144 0.025481621787366335 0.047191484166678156 3.035122209861312e-06 5.517823817274111 -0.0722365271403067 CIPALDSLTPANEDQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CIPALDSLTPANEDQK 16 0 P10809 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 117.79 0.0021783 0.0 6212.3 5810.5 8279.1 7876.9 8328.5 7378.5 7545.8 6027.6 5970.3 6307.2 False True 7263.919691482098 6387.328039743286 8476.505142661592 7435.582830254355 6696.590211637495 6991.558470893105 6831.007197138917 5869.381886770108 6057.604342802079 7450.645432232275 0.9749383134053887 0.8572851973482772 1.1376873614185612 0.9979783493772556 0.8987933022107509 0.9383829272893444 0.9168342876158436 0.7877682464097064 0.8130308169808009 1.0 12.863149692994922 -6.9267279977157585 1.3054042579861571 0.859105247020399 0.9858937764449003 0.22267523188449778 0.08595151650661083 0.6108025785359901 2.14976660989014 0.046115055807962775 0.03581778521689968 1.1837827366746272e-07 6.9267279977157585 0.12678852942450125 CIPALDSLTPANEDQK ddPTM_PC-9_Lapatinib_30min_R1 2 CIPALDSLTPANEDQK 16 0 P10809 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 ; 232.5 2.0134e-29 8070800.0 41065.0 34476.0 38240.0 32887.0 33858.0 33156.0 31380.0 22820.4 39090.0 32363.0 False True 40479.40556960131 34396.17294019914 35096.05481066873 35305.61968781595 31866.53900738916 31737.995170411017 33004.70285648078 23880.719093966047 34687.272564051345 37956.901429013145 1.066457061709996 0.9061902222057492 0.9246290790175599 0.9301502061184944 0.8395453213425718 0.836158747830544 0.8695310105385196 0.6291535450707871 0.9138594368384719 1.0 15.212074603851164 -2.5669160100148956 0.4996055499994678 0.8299119391393817 3.0911080702133296 0.28796659241262357 0.09272800411054323 41.77135749500031 1.2793805132938718 0.05040411246004243 87.69369937110046 0.002710715817614458 2.5669160100148956 2.261196131073948 CKLEEMGFKDTDPDS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CKLEEMGFKDTDPDSK 16 2 B1AMS2;Q14141-2;Q14141-4;Q14141;H0Y961;D6RDU5;Q9NVA2-2;D6RGI3;D6RER5;Q9NVA2 B1AMS2;D6RGI3 SEPT6;SEPT11 Septin-6;Septin-11 1 CKLEEMGFKDT(0.051)DPDS(0.949)K 59.708999999999996 0.043655 2372000.0 1385.2 0.0 1248.7 2501.4 2390.2 3697.9 1641.9 1865.4 2618.4 1928.5 True False 1619.6870010529121 0.0 1278.4737437211215 2361.254667648219 1921.8574681942655 3503.975614219098 1486.3673456734061 1816.4352265546747 2656.6891464738733 2278.1217840023996 0.710974721556504 0.0 0.5611963999022868 1.0364918522923583 0.8436148943792555 1.5380984628762968 0.6524529795163226 0.7973389479483426 1.1661752085116248 1.0 11.15362915746756 -5.633671071985502 4.01607904572927 0.997076091748211 0.338794318220183 0.488578823284344 0.2764215185569742 0.17297031802468898 5.095377208271028 0.07503312206379922 0.13638396425963245 2.324496668134219e-06 5.633671071985502 -0.658281773528028 CLDSNEQLERLNLSGNQICS(ph)FK ddPTM_PC-9_AZD4547_30min_R2 1 CLDSNEQLERLNLSGNQICSFK 22 1 A0A2R8Y4H4;Q6ZRR7-2;Q6ZRR7 A0A2R8Y4H4 LRRC9 Leucine-rich repeat-containing protein 9 1 CLDSNEQLERLNLS(0.011)GNQICS(0.988)FK 43.848 0.036169 23606000.0 44733.0 60988.0 81174.0 136360.0 104010.0 85316.0 71782.0 99491.0 65303.0 92480.0 True False 58957.163495798406 80701.17831465743 80097.57972185052 104924.30874099891 89570.00684328533 79981.17703299265 78170.45893983995 84116.95202573886 68754.78326128332 89242.30334872105 0.6606414366673038 0.9042928665714899 0.8975292738564038 1.1757238977909303 1.0036720645060422 0.8962249295657482 0.8759350219187304 0.9425681416698257 0.7704281566178184 1.0 16.445440129649803 -4.687752877544471 2.4049933291558694 0.948383845937696 0.5441150393132898 0.4192795075784622 0.0998459092626372 0.8538450719985203 4.797994506459026 0.0276131773007513 0.7976256344510708 2.0523296642477838e-05 4.687752877544471 -0.40426880662440623 CLDSNEQLERLNLSGNQICS(ph)FK ddPTM_PC-9_Lapatinib_30min_R1 1 CLDSNEQLERLNLSGNQICSFK 22 1 A0A2R8Y4H4;Q6ZRR7-2;Q6ZRR7 A0A2R8Y4H4 LRRC9 Leucine-rich repeat-containing protein 9 1 CLDSNEQLERLNLS(0.01)GNQICS(0.99)FK 45.236999999999995 0.031396 20436000.0 41220.0 91314.0 147500.0 127390.0 125980.0 132010.0 120200.0 118570.0 142730.0 103130.0 True False 40632.195241177804 91102.56804331556 135373.1193664651 136758.6855605824 118570.10408620976 126364.24003034014 126423.36785688315 124079.19506106598 126654.24438646832 120955.88308791278 0.33592574584938245 0.7531883999152045 1.1191941715482632 1.1306493084026668 0.980275626610332 1.0447134674590113 1.0452023054140864 1.02582191038102 1.0471110718476908 1.0 16.88412141568805 -4.893944505016119 2.521371654980742 1.049464679837683 0.2679220502080692 0.9546312358787402 0.04827532641185419 0.07682901689943843 0.755608006294586 0.013494081818229276 0.11773080430135795 1.2766019250378716e-05 4.893944505016119 -0.7815426296296137 down CLEEFELLGK ddPTM_PC-9_Lapatinib_30min_R1 2 CLEEFELLGK 10 0 Q99613-2;Q99613;B5ME19;H3BPE4;H3BPE3;H3BTY8 Q99613-2 EIF3C;EIF3CL Eukaryotic translation initiation factor 3 subunit C;Eukaryotic translation initiation factor 3 subunit C-like protein 0 ; 127.4 0.00035372 1787200.0 39728.0 30729.0 35953.0 34550.0 29975.0 28370.0 26971.0 27377.0 32334.0 26707.0 False True 39161.471434777064 30657.848888484128 32997.08312259344 37090.922255421334 28211.929433117435 27156.68123370008 28367.42640988347 28649.03536465217 28692.20442788531 31323.26936515942 1.2502357585423698 0.978756353019285 1.0534367513786982 1.1841331702327733 0.9006700132169888 0.866981058621748 0.9056342771625331 0.914624684628809 0.9160028633473165 1.0 14.93494718128253 -6.275286978063653 24.900457794214944 0.9099489235329621 1.1022770849718175 0.6256877744060779 0.07506903828657513 497.95032697736787 895401.7406994201 0.02275289310077452 0.02592729225550089 5.305337562283744e-07 6.275286978063653 0.19232816143885545 CLHEDPQS(ph)PPPLPAEKPIGNTFSTVSGK ddPTM_PC-9_AZD4547_30min_R2 1 CLHEDPQSPPPLPAEKPIGNTFSTVSGK 28 1 A0A0U1RQE4;A0A494C1M0;Q5HYK7-2;Q5HYK7 A0A0U1RQE4 SH3D19 SH3 domain-containing protein 19 1 CLHEDPQS(0.999)PPPLPAEKPIGNTFSTVSGK 73.649 2.0997e-05 7742100.0 14193.0 12056.0 17944.0 25513.0 19586.0 19535.0 15057.0 21407.0 16884.0 17234.0 True False 18706.078767260573 15952.8662320704 17706.05083559867 19631.372021920684 16866.821978969212 18313.473361849025 16397.043830725986 18099.04003392256 17776.45377063085 16630.642905621342 1.1247958887348672 0.9592453113570345 1.0646642427523851 1.1804337410963868 1.014201439757211 1.1011885388783658 0.9859536954631865 1.0882946700638303 1.0688975688740339 1.0 14.021556320803827 -9.64592338061638 9.311746713888173 1.0000000000813034 1.0634413801854803 0.08931448093546845 0.06229857253757736 0.0 0.0 0.05850046292545479 0.014188446340540005 2.259834421032803e-10 9.64592338061638 0.06344138010417688 CLHEDPQS(ph)PPPLPAEKPIGNTFSTVSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CLHEDPQSPPPLPAEKPIGNTFSTVSGK 28 1 A0A0U1RQE4;A0A494C1M0;Q5HYK7-2;Q5HYK7 A0A0U1RQE4 SH3D19 SH3 domain-containing protein 19 1 CLHEDPQS(1)PPPLPAEKPIGNTFSTVSGK 55.977 0.0012682000000000001 6938800.0 49930.0 39278.0 36339.0 48936.0 70253.0 73290.0 70781.0 68239.0 75382.0 58090.0 True False 58382.16283754828 43177.26026074118 37205.459576424924 46194.27457265258 56487.42896538016 69446.54338032872 64076.111269936904 66447.79855519715 76484.31914126719 68621.25715981291 0.8507883016713221 0.6292111518765259 0.5421856304639925 0.6731773284926877 0.8231768303781709 1.0120266846553654 0.9337647534015479 0.9683267445894503 1.1145863877594357 1.0 16.066367936246735 -6.525793762132827 2.4616745239384668 1.0013867901802136 0.6605716231209628 0.775018165577236 0.08418882595727094 0.13953927794043447 1.7017723593380951 0.030991200716158067 0.033160659109135335 2.979931203919397e-07 6.525793762132827 -0.34081516705925075 CLHEDPQS(ph)PPPLPAEKPIGNTFSTVSGK ddPTM_PC-9_Lapatinib_30min_R1 2 CLHEDPQSPPPLPAEKPIGNTFSTVSGK 28 1 A0A0U1RQE4;A0A494C1M0;Q5HYK7-2;Q5HYK7 A0A0U1RQE4 SH3D19 SH3 domain-containing protein 19 1 CLHEDPQS(0.999)PPPLPAEKPIGNTFSTVSGK;CLHEDPQS(1)PPPLPAEKPIGNTFSTVSGK 84.947 2.0074e-07 21461000.0 101283.0 102210.0 120033.0 85341.0 147046.0 195921.0 207484.0 193883.0 195087.0 165544.0 True False 99838.68584697276 101973.33902476377 110164.35008077945 91617.2618292306 138397.04338355904 187541.91554415753 218226.5062929912 202891.51198469 173114.24770281615 194158.0598264854 0.5142134503002157 0.5252078595959138 0.567395194303192 0.4718694753702568 0.7128060689689694 0.9659239266799402 1.123963159129295 1.0449811466287287 0.891615047335786 1.0 17.566872071615478 -6.633856347856702 2.5755629608212702 1.0224543954027951 0.5246534597501958 0.9373937102866009 0.05942958785404428 0.06412304513119878 0.8642948479741179 0.022179696434389582 0.02216527896738378 2.3235052180679258e-07 6.633856347856702 -0.4978009356525993 CLLADLPLPPELPGGDDLS(ph)KSPEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CLLADLPLPPELPGGDDLSKSPEEK 25 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YF61;A0A2R8YCQ1;A0A2R8Y7Y0;A0A087X209;Q9BVE2 Q14004 CDK13 Cyclin-dependent kinase 13 1 CLLADLPLPPELPGGDDLS(0.5)KS(0.5)PEEK 74.3 0.0012061 0.0 19700.0 18856.0 11625.0 16891.0 18295.0 13068.0 16224.0 11348.0 13796.0 14205.0 True False 23034.820907264195 20727.899065037323 11902.184088058004 15944.652031360869 14710.226081756378 12382.691075100776 14687.145268411812 11050.12702419988 13997.74040053222 16780.25405328186 1.372733740152109 1.2352553780902613 0.7092970136367029 0.9502032556081852 0.8766390565391572 0.7379322765783147 0.8752635819324391 0.6585196498880607 0.8341792893054895 1.0 14.0344769379157 -5.147211649840611 4.423073772668098 0.8228641251096789 1.3411985801966644 0.777477420316617 0.10211238065435929 0.09152966998700651 2.8632992049702914 0.025491771468136575 0.0752148654866201 7.125057117088064e-06 5.147211649840611 0.5183344550869855 CLLADLPLPPELPGGDDLSKS(ph)PEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CLLADLPLPPELPGGDDLSKSPEEK 25 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YF61;A0A2R8YCQ1;A0A2R8Y7Y0;A0A087X209;Q9BVE2 Q14004 CDK13 Cyclin-dependent kinase 13 1 CLLADLPLPPELPGGDDLS(0.083)KS(0.917)PEEK 97.771 9.979500000000001e-07 2728500.0 18219.0 16973.0 12580.0 19819.0 17936.0 12524.0 19904.0 15877.0 13128.0 15627.0 True False 21303.116858347537 18657.967269350793 12879.95490991568 18708.605684064943 14421.56955465331 11867.21939275805 18018.549027519028 15460.245573072028 13319.972164264065 18460.051396736064 1.154011784718766 1.0107213066941798 0.6977204252092708 1.01346444178226 0.7812312785436338 0.6428594990183127 0.9760833618645776 0.837497428409412 0.7215566131424304 1.0 14.172118949310656 -5.0268384562465265 4.611747924639443 0.830910825706814 1.1303652531995927 0.4157602602650967 0.12315838920535128 0.16276591893793194 8.709406067677438 0.030539161218204935 0.10405385948325555 9.400729228075475e-06 5.0268384562465265 0.29945442749277873 CLLTFPSPEQLEIS(ph)GIIHMNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CLLTFPSPEQLEISGIIHMNK 21 0 A0A096LNH2 A0A096LNH2 EFCAB8 1 CLLT(0.027)FPS(0.18)PEQLEIS(0.793)GIIHMNK 45.257 0.042374 12508000.0 8286.5 8678.8 9425.1 8680.1 10344.0 6319.1 7755.6 8113.6 6075.0 5688.5 True False 9689.24078416471 9540.373907808964 9649.830128890797 8193.78213826389 8317.167455025312 5987.715271860217 7020.933422318454 7900.626597069807 6163.835382229141 6719.780019858777 1.4418985079169806 1.4197449737364265 1.4360336350852148 1.2193527338765608 1.2377142451755594 0.8910582272284049 1.0448159614704182 1.1757269692938321 0.9172674349477707 1.0 12.714198290068886 -6.171913400872665 1.382147542215411 1.02222455736331 1.4402954654989792 0.8010102688739015 0.08918118801099371 0.18321484726316542 0.705467737599817 0.03320278903881096 0.05054467150621509 6.731108624611301e-07 6.171913400872665 0.4180709081356693 CLPTSDS(ph)SPEPQQPPEDR ddPTM_PC-9_Lapatinib_30min_R1 1 CLPTSDSSPEPQQPPEDR 18 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 CLPT(0.001)S(0.007)DS(0.496)S(0.496)PEPQQPPEDR 184.02 1.6021e-10 4383000.0 12280.0 11466.0 15410.0 16228.0 16916.0 14355.0 10852.0 12574.0 15521.0 11992.0 True False 12104.884948123807 11439.451181468936 14143.049284320214 17421.46125502105 15921.034138135594 13741.070113139407 11413.863460756196 13158.233943643809 13772.861536624227 14064.801221664415 0.8606509795160352 0.8133389872477133 1.005563396270064 1.2386567702205615 1.131977188103588 0.9769828877477233 0.8115197137073716 0.9355435413744636 0.979243241305785 1.0 13.779801542685853 -10.390732030337315 14.754330973656051 1.000068528523841 0.9757062529750418 0.003607784128058178 0.12753049889364917 0.0 0.0 0.14021840168744595 0.034007957694860314 4.066941914133793e-11 10.390732030337315 -0.024362275548799328 CLQLS(ph)PPSQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CLQLSPPSQSK 11 0 Q9HBH9 Q9HBH9 MKNK2 MAP kinase-interacting serine/threonine-protein kinase 2 1 CLQLS(0.956)PPS(0.043)QS(0.001)K 88.163 0.0099777 3055100.0 17102.0 19853.0 19940.0 23217.0 27188.0 18303.0 24749.0 17764.0 17686.0 17088.0 True False 19997.030820103148 21823.87463609387 20415.4452228711 21916.226760529575 21860.706570691043 17343.15845940997 22404.595552756637 17297.713822513808 17944.624291375247 20185.91913146644 0.9906425706883545 1.0811434690667188 1.0113706039298884 1.0857185455759544 1.0829681040688355 0.8591711056830161 1.109912083113008 0.856919801860773 0.8889674121106831 1.0 14.301061658526352 -6.742125482138918 24.996855620516254 0.9444839182250864 1.0518757077341097 0.3363162026943245 0.07538913169452086 287.52309671980663 372123.6518647739 0.02437287292771952 0.024338231033837428 1.8108168117449507e-07 6.742125482138918 0.10739178950902328 CLST(ph)TPPGDMAHAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CLSTTPPGDMAHAR 14 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 CLS(0.045)T(0.478)T(0.478)PPGDMAHAR 73.593 0.020105 9876100.0 43944.0 34431.0 41305.0 54607.0 55214.0 52444.0 53162.0 54986.0 53116.0 33650.0 True False 51382.85126643744 37849.08213344825 42289.86785008483 51547.54682828265 44395.213057015404 49693.74431761444 48126.11050045048 53542.67576248278 53892.72101440051 39750.47862674657 1.2926347818077315 0.9521667019118875 1.06388323640535 1.2967780164940779 1.1168472579634192 1.2501420368854987 1.210705183007992 1.3469693350171632 1.3557753988435794 1.0 15.27868461122384 -5.752512910493083 24.989395246910185 1.2356798139141294 1.0878220511923984 0.15645315979525865 0.12726509989523144 292.2441627768378 818120.9791555221 0.03367755658157796 0.057252036062814336 1.7680196581329393e-06 5.752512910493083 -0.147857762721731 CLSTT(ph)PPGDMAHAR ddPTM_PC-9_Lapatinib_30min_R1 1 CLSTTPPGDMAHAR 14 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 CLS(0.001)T(0.012)T(0.987)PPGDMAHAR 77.726 0.014775 7828500.0 43462.0 39061.0 39699.0 41788.0 50894.0 39711.0 36109.0 32614.0 51395.0 36565.0 True False 42842.22391004534 38970.556654400694 36435.10146257159 44861.2289206815 47900.514981453816 38012.65310086232 37978.54733730605 34129.3655032606 45606.35388665693 42885.2115302001 0.9989976120293942 0.908717836845863 0.8495959367464869 1.0460768950408434 1.1169471543289906 0.8863813828711913 0.8855861025790036 0.7958306438392273 1.0634517648243518 1.0 15.388192616313257 -9.89639048435669 15.179645561205982 1.000002073766475 0.9454085864578725 0.020634914640022317 0.0981470022240273 0.0 0.0 0.09900426223461484 0.024012060622333332 1.2694322156512247e-10 9.89639048435669 -0.05459348730860247 CLTAIVK ddPTM_PC-9_Lapatinib_30min_R1 1 CLTAIVK 7 0 P04083 P04083 ANXA1 Annexin A1 0 108.09 0.045208 11255000.0 107600.0 105110.0 129280.0 98188.0 122800.0 96569.0 88506.0 106780.0 97918.0 127330.0 False True 106065.60426857689 104866.62425293922 118651.09743523164 105409.07306556597 115577.14543408921 92438.96898333394 93088.40761681613 111741.388619555 86889.44371774826 149338.8208434396 0.7102346440767167 0.7022060550677367 0.7945094032824884 0.7058383913187067 0.7739256596598906 0.6189882072273958 0.6233369668453859 0.748240731970824 0.5818275732124564 1.0 17.188229719334444 -10.797796189859357 5.252300321286984 1.0000468956067938 0.6983637739222507 0.6589495467439282 0.06569857730389835 3.630976239984578e-05 5.012602990020101e-06 0.0640215689742706 0.015525102703319589 1.5929561103459375e-11 10.797796189859357 -0.30168312168454314 CLTTDEYDGHSTYPSHQYQ ddPTM_PC-9_AZD4547_30min_R2 1 CLTTDEYDGHSTYPSHQYQ 19 0 A0A2R8YEP4;P30043;M0R192 A0A2R8YEP4 BLVRB Flavin reductase (NADPH) 0 105.0 0.00020866 5396200.0 0.0 3212.0 18485.0 34135.0 21156.0 17426.0 10036.0 20460.0 12536.0 23064.0 False True 0.0 4250.216185916566 18239.876822115562 26265.703130492802 18218.854579141866 16336.34946524604 10929.184557691833 17298.377124027455 13198.627367248768 22256.536380135225 0.0 0.19096485245161687 0.8195289918693424 1.180134351629659 0.8185844494385416 0.7340023257089917 0.4910550487741898 0.7772268257996734 0.593022523443002 1.0 14.441941473756671 -5.1904654800355585 4.043445380443031 0.795352165511061 0.04978399279083577 0.7070398888229089 0.18311619797877568 0.1294373420329914 4.089702619493677 0.05158881154102619 0.15163616667537316 6.449625827819641e-06 5.1904654800355585 -0.7455681727202252 down CLTTDEYDGHSTYPSHQYQ ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CLTTDEYDGHSTYPSHQYQ 19 0 A0A2R8YEP4;P30043;M0R192 A0A2R8YEP4 BLVRB Flavin reductase (NADPH) 0 79.393 0.002352 3518600.0 8498.3 8887.2 20527.0 21060.0 22704.0 21932.0 20314.0 15762.0 20411.0 17819.0 False True 9936.894340924026 9769.462482541352 21016.44152908102 19880.076477441216 18255.314182027716 20781.84731092058 18389.710859376064 15348.26420121947 20709.47226118172 21049.4436448736 0.47207396587624606 0.464119748120783 0.998432162087067 0.9444466472767239 0.867258749923 0.9872872490851704 0.8736435589286803 0.7291529629077583 0.983848913566194 1.0 14.36149448165874 -5.254967214782137 24.98295680238332 0.9126428558033509 0.4680967911480787 0.8378256554974608 0.0799534237870805 186.98380754819442 721764.1655750063 0.020828595275462495 0.05237251317393645 5.559462244859421e-06 5.254967214782137 -0.44454606465527224 CLTTDEYDGHSTYPSHQYQ ddPTM_PC-9_Lapatinib_30min_R1 1 CLTTDEYDGHSTYPSHQYQ 19 0 A0A2R8YEP4;P30043;M0R192 A0A2R8YEP4 BLVRB Flavin reductase (NADPH) 0 84.859 0.0011155999999999998 5679600.0 8164.0 7711.4 9003.6 8369.3 7511.3 10527.0 6965.0 7324.7 10467.0 8391.3 False True 8047.579862905758 7693.544727086999 8263.358762901074 8984.806241166354 7069.500101783983 10076.784749635564 7325.6136199932635 7665.032302131997 9288.09623760362 9841.72502429558 0.8177001331615402 0.7817272590012911 0.8396250395638871 0.9129300218189585 0.7183192056607964 1.0238839964294582 0.7443424401625764 0.7788301627214607 0.9437467735254486 1.0 13.26469549310057 -8.44590899950451 4.5437173026233255 0.9988259873313905 0.8295589760647752 0.33366777488868404 0.08344222475018007 0.21992898009434697 7.890458848629619 0.07684430337735831 0.02006526211198223 3.5817147919707202e-09 8.44590899950451 -0.16926701126661525 CLVAGLLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 CLVAGLLSPR 10 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 CLVAGLLS(1)PR;CLVAGLLS(1)PR 75.652 0.024213 8684000.0 29054.0 28685.0 30038.0 51737.0 38404.0 31657.0 33475.0 37768.0 29730.0 33524.0 True False 38292.56763925797 37956.86528425178 29639.676493519462 39809.83397868187 33072.26750129344 29677.482785567165 36454.210150332205 31931.82342230054 31301.46710500208 32350.33496391145 1.1836838067357078 1.1733067161930384 0.9162092610968056 1.2305849081034832 1.0223160761144312 0.9173779133561988 1.1268572702878918 0.9870631465770668 0.9675778362085141 1.0 14.981493029890016 -1.5228787453303763 0.3604715939017014 0.9976481925764902 3.4536318642185875 0.28554272657326585 0.09299384871249243 85.79736813858473 1.197027300640938 0.07537150197045302 144.64142951112643 0.029999999996543448 1.5228787453303763 2.4559836716420973 CLVAGLLS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 CLVAGLLSPR 10 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 CLVAGLLS(1)PR;CLVAGLLS(1)PR 95.48299999999999 0.0058993000000000006 7429500.0 36587.0 33367.0 32034.0 41356.0 50837.0 44709.0 47862.0 37088.0 37281.0 33937.0 True False 42780.45647381094 36679.455245179255 32797.81204962153 39038.95739796102 40875.85478645798 42364.3813343037 43328.16486912757 36114.47929798424 37826.16409627728 40089.509454855805 1.0671234708418014 0.9149389888764651 0.8181145764967429 0.9737948388199213 1.0196147406714384 1.0567448170452072 1.0807856084624523 0.9008461263077367 0.9435427025833967 1.0 15.290937143973112 -4.740320286616242 24.548556519591937 0.9679702526036221 1.0671239314327974 0.14010545547556807 0.07396391555489995 3095.269559430129 3597668.1822715397 0.020553721505006887 0.902131376548378 1.8183593472751972e-05 4.740320286616242 0.09915367882917525 CLVAGLLS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 CLVAGLLSPR 10 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 CLVAGLLS(1)PR 82.831 0.014376 3510400.0 20534.0 17389.0 21039.0 13803.0 13806.0 15438.0 14597.0 14709.0 15090.0 13111.0 True False 20241.181394525593 17348.736838876965 19309.254632888576 14818.118665458182 12993.958223640338 14777.752727735708 15352.761236330469 15392.433837844485 13390.405295255443 15377.218880690647 1.316309636454657 1.1282103073047869 1.2557052600152185 0.9636410055959772 0.845013544026287 0.9610159575924554 0.9984094884419646 1.0009894479145993 0.8707949987022641 1.0 13.908506981038643 -5.775869091059912 11.128934401694183 0.9467879483384736 1.2229231585688352 0.7951143682298811 0.0661956412132311 0.16005783461086032 120.90720850310808 0.018341047929477047 0.02798861382837847 1.675447828438865e-06 5.775869091059912 0.2761352102303616 CMPTFQFFK ddPTM_PC-9_Lapatinib_30min_R1 1 CMPTFQFFK 9 0 P10599-2;P10599 P10599-2 TXN Thioredoxin 0 108.98 0.011056 6432800.0 11916.0 10316.0 13492.0 12251.0 14301.0 9537.0 11899.0 10860.0 13335.0 11152.0 False True 11746.075654873224 10292.11393581315 12382.739840626102 13151.979408137953 13459.843296847788 9129.124741832844 12515.07199774585 11364.595246379165 11833.07187622474 13079.608340894058 0.8980449069066176 0.7868824254954435 0.9467209963704218 1.0055331218915495 1.0290708212389592 0.6979662161052769 0.9568384367150233 0.8688788647323011 0.9046961933277499 1.0 13.675031720606416 -12.257993497737312 1.6276853168551262 2.583961138255795 0.8992877291931359 0.09396788823423674 0.09370940600545002 4780112.340882863 150659.18469401158 27973487.132399052 0.0252764805892301 5.520857050533082e-13 12.257993497737312 -1.6846734090626594 CMVEVPQELETS(ph)TGHSLEK ddPTM_PC-9_AZD4547_30min_R2 2 CMVEVPQELETSTGHSLEK 19 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 CMVEVPQELET(0.143)S(0.7)T(0.143)GHS(0.014)LEK;CMVEVPQELET(0.178)S(0.802)T(0.019)GHS(0.001)LEK 103.24 0.00020795 16813300.0 85770.0 76709.0 95722.0 103177.0 98645.0 121253.0 89500.0 142200.0 106730.0 106543.0 True False 113043.07587317236 101503.68412374647 94452.66373635629 79391.13671875956 84949.84448664433 113671.0307419648 97465.32661552589 120226.25743092378 112371.52990638638 102812.96199916521 1.0995021802220835 0.9872654395908818 0.9186843944552749 0.7721899571320995 0.8262561727122897 1.1056099204970649 0.947986758871097 1.1693686777733332 1.0929704554888593 1.0 16.649662636177403 -6.773650147714065 24.999713959923053 1.0665726970221248 0.9161018946876944 0.3384552575682792 0.09938401926894358 280.02445869517925 573304.5200916671 0.03776813149311436 0.03354889474868824 1.6840301099447696e-07 6.773650147714065 -0.15047080233443033 CMVEVPQELETS(ph)TGHSLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 CMVEVPQELETSTGHSLEK 19 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 CMVEVPQELET(0.228)S(0.757)T(0.015)GHSLEK;CMVEVPQELET(0.021)S(0.876)T(0.063)GHS(0.04)LEK 101.33 0.00027767 16082700.0 64496.0 78259.0 75744.0 71974.0 82451.0 61503.0 73109.0 62806.0 55457.0 44206.0 True False 75413.89894593459 86028.03632428683 77550.02422071951 67941.53012285636 66295.31842945589 58277.674410156375 66183.5862566763 61157.409048457695 56267.95371066359 52220.19786549656 1.4441519187686342 1.6474092370517064 1.4850580310029642 1.301058458220576 1.2695340335594398 1.115998728313172 1.2673943983733116 1.1711447207837222 1.077513223055815 1.0 15.672320303669562 -6.004177796750126 1.1567058660635432 1.1404870410886636 1.5671571804799982 0.8032847347368215 0.08447974497809327 0.2112991678167307 0.5752557304615908 0.032158986554837406 0.06326045272401967 9.90426389097447e-07 6.004177796750126 0.4266701393913346 CMVEVPQELETS(ph)TGHSLEK ddPTM_PC-9_Lapatinib_30min_R1 2 CMVEVPQELETSTGHSLEK 19 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 CMVEVPQELET(0.034)S(0.74)T(0.203)GHS(0.023)LEK;CMVEVPQELET(0.175)S(0.656)T(0.169)GHSLEK 111.67 8.479e-05 16304500.0 63680.0 75138.0 96799.0 81143.0 80825.0 89554.0 78485.0 68536.0 77896.0 72802.0 True False 62771.91152251824 74964.02257746512 88840.55987494547 87110.52690511303 76071.03240806387 85723.98418057027 82548.56926994573 71720.43276296895 69122.53219875529 85385.72869743255 0.7351569457813354 0.8779455738218604 1.0404614591948407 1.0202000759845051 0.8909103847743028 1.003961499050226 0.966772439952578 0.8399580803147201 0.8095326145624816 1.0 16.381707338646137 -10.541084071360896 14.73826346018726 0.9999999998410637 0.9174972568648113 0.07112881776943814 0.0942125508026749 0.0 0.0 0.09684064043901534 0.023487305432789433 2.8768414576528156e-11 10.541084071360896 -0.08250274297625237 CNAEEHVR ddPTM_PC-9_AZD4547_30min_R2 1 CNAEEHVR 8 0 P11279-2;P11279 P11279-2 LAMP1 Lysosome-associated membrane glycoprotein 1 0 116.37 0.0014945 0.0 8126.4 8538.8 8113.6 9949.3 8144.6 6890.5 6934.3 9590.9 10522.0 7989.1 False True 10710.42616037951 11298.800114665126 8006.00836266794 7655.642600152685 7013.862876029442 6459.635945729241 7551.439266480921 8108.846781956738 11078.171438911264 7709.4040406927825 1.389267718210946 1.4655867113756555 1.0384730545201135 0.9930265114843733 0.9097801644599188 0.8378904402510424 0.9795101186319888 1.0518124019905513 1.436968588030542 1.0 12.912403624598989 -5.267611426517763 20.16991674561423 1.0183713075450258 1.4274274177747899 0.5249133408775202 0.15050375684740355 24.5899531079182 80366.01369671444 0.04132668911116796 0.09053709363359565 5.3999355136344295e-06 5.267611426517763 0.40905611022976407 CNAEEHVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CNAEEHVR 8 0 P11279-2;P11279 P11279-2 LAMP1 Lysosome-associated membrane glycoprotein 1 0 94.309 0.007703100000000001 0.0 6668.1 8780.9 8052.9 7849.4 14625.0 8837.7 7362.9 7827.1 7744.5 7342.6 False True 7796.877629021742 9652.609721053574 8244.911676793321 7409.623566098152 11759.336236440946 8374.23545411831 6665.4328092202495 7621.646918497958 7857.748661345448 8673.75525601038 0.8989044997112392 1.1128524423564878 0.9505584874648272 0.8542578557267613 1.3557376118368625 0.9654682668519474 0.7684598668611861 0.8787020954063264 0.9059223403727596 1.0 13.082441020470714 -7.00358674486542 24.99773642482992 0.876563061434218 1.0377903460749365 0.1938166790067677 0.13967718274634836 231.2142178863981 1611451.8466095058 0.049846768718897 0.04304523527562202 9.917752248157868e-08 7.00358674486542 0.16122728464071845 CNEPAVWSQLAK ddPTM_PC-9_Lapatinib_30min_R1 2 CNEPAVWSQLAK 12 0 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 ; 155.02 0.00041887 3173900.0 33526.0 34674.0 31303.0 34672.0 30866.0 27990.0 36037.0 30863.0 28240.0 28675.0 False True 33047.913092084564 34593.71448336422 28729.388173074352 37221.89454240139 29050.52256489084 26792.932947876823 37902.819529604785 32297.00765092084 25059.313819616535 33631.43554296423 0.982649493206015 1.0286124848631775 0.8542421014521517 1.106759017016991 0.863790739107129 0.7966633750631547 1.1270056992120914 0.9603220061677518 0.7451157946440676 1.0 15.037522740528543 -6.342843932769054 24.99999957986341 0.9181343173431794 0.9857138503190143 0.09603689188939435 0.11555930809225713 290.81040847546393 89306.90768773957 0.036252966458827196 0.04110700618033785 4.541047735518785e-07 6.342843932769054 0.06757953297583486 CNNVLYIR ddPTM_PC-9_Lapatinib_30min_R1 1 CNNVLYIR 8 0 P62306 P62306 SNRPF Small nuclear ribonucleoprotein F 0 115.46 0.016738999999999997 2642700.0 22142.0 14068.0 15793.0 17636.0 15121.0 15415.0 16834.0 17185.0 15325.0 15518.0 False True 21826.25101965449 14035.426410335338 14494.560502742968 18933.01027197136 14231.612509029812 14755.736384120091 17705.58215060539 17983.47783692689 13598.937120595738 18200.265623564734 1.1992270591586873 0.7711660203553852 0.7963928001125535 1.0402601073831532 0.7819453190069643 0.8107429138295186 0.9728199860820244 0.9880887569928013 0.7471834423662784 1.0 14.151671885523045 -4.749309884079879 24.96755098409228 0.8786265014613222 1.1992278006466848 0.4538295501947789 0.10547712146061779 517.2003025202249 1064547.3451422413 0.025848840834522196 0.4282254618295526 1.7811074323962267e-05 4.749309884079879 0.3206012991853626 CNTPDPS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 CNTPDPSK 8 0 P14784 P14784 IL2RB Interleukin-2 receptor subunit beta 1 CNTPDPS(1)K 73.039 0.031041000000000003 6409200.0 21996.0 25124.0 28156.0 19997.0 21387.0 24382.0 18512.0 18088.0 25997.0 20742.0 True False 21682.333006427627 25065.82692161396 25841.122365303057 21467.646088036476 20129.05870845979 23339.238697218032 19470.460780088335 18928.434513490472 23068.944099453664 24327.227063022303 0.8912784408291667 1.030361037724449 1.0622304917185525 0.8824534761985912 0.8274292280132584 0.9593875469964258 0.8003567660896167 0.7780761228747659 0.948276761658494 1.0 14.570284263721549 -5.839996543524324 8.162995515183486 0.8725175949012104 0.9979000262230177 0.2785961085858961 0.07893991791684245 0.27876483695901827 25.45473011793058 0.021930961568857137 0.03267841507234314 1.4454512748001995e-06 5.839996543524324 0.12538243132180726 CPARLS(ph)DSENEEPSR ddPTM_PC-9_Lapatinib_30min_R1 1 CPARLSDSENEEPSR 15 1 Q8NCN4 Q8NCN4 RNF169 E3 ubiquitin-protein ligase RNF169 1 CPARLS(0.797)DS(0.201)ENEEPS(0.002)R 55.907 0.032361 5252800.0 15943.0 14371.0 20707.0 18561.0 21191.0 20155.0 15851.0 18785.0 23780.0 14941.0 True False 15715.649896411875 14337.72483245161 19004.550391331526 19926.037857680898 19944.587043108986 19293.017633599753 16671.68722046134 19657.81967801405 21101.64598549863 17523.53194236891 0.8968311838102748 0.8181983449230025 1.0845159785044114 1.1371016940656318 1.138160224131893 1.1009776851521882 0.9513885257430349 1.1217955228811376 1.204189090127342 1.0 14.09700596511607 -5.26920576545797 23.85870472730039 1.0951360823655114 0.8575147574910804 0.641828108244686 0.07012002780975096 170.9707651507126 525233.3593503534 0.018762113799370695 0.040342115547484396 5.3801481474885405e-06 5.26920576545797 -0.237621324874431 CPEPGSASWR ddPTM_PC-9_AZD4547_30min_R2 1 CPEPGSASWR 10 0 H7C5R6 H7C5R6 ARID4B 0 66.29899999999999 0.039082 1174000.0 3826.8 3946.3 4278.6 4756.3 5072.1 3965.5 5442.0 4059.2 3084.9 4412.8 False True 5043.642797615213 5221.86430089743 4221.862968412425 3659.808519102472 4367.926465818938 3717.5366581219546 5926.32745744908 3431.9439111364736 3247.9615160518306 4258.309215151783 1.1844238036235322 1.2262764484826878 0.9914411460281757 0.859451095303332 1.0257419659138698 0.8730076822261595 1.3917090464830986 0.8059405124750072 0.7627350086496855 1.0 12.056064998888383 -5.294995137210296 5.860246430329376 0.9664455816420358 1.2060800344141618 0.2543711336514928 0.1655941521006826 0.24460291677363935 25.964531793525342 0.0442933085305411 0.09800063950602132 5.069963850748978e-06 5.294995137210296 0.23963445277212603 CPFPAGAALACCS(ph)EDEEDDEEHEGGGSR ddPTM_PC-9_Lapatinib_30min_R1 1 CPFPAGAALACCSEDEEDDEEHEGGGSR 28 0 Q147X3 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 CPFPAGAALACCS(1)EDEEDDEEHEGGGSR 144.43 5.4318e-10 4314400.0 5663.3 10286.0 12681.0 10880.0 14895.0 12784.0 10406.0 13779.0 11249.0 11833.0 True False 5582.540303477973 10262.18339896996 11638.417130075568 11680.151494616039 14018.905384696725 12237.258120959532 10944.771763050956 14419.222642712577 9982.019162778557 13878.318283518603 0.4022490469978339 0.7394399803582085 0.8386042813196566 0.8416114442689335 1.010129981047133 0.8817536729570515 0.7886237755512912 1.0389747769249775 0.7192527912141089 1.0 13.760545138314285 -4.577255687067663 1.3520472448697323 0.8968062880209817 9.348485961862105e-13 0.7095282929766132 0.09533529456902028 1.061604560088755 1.2258103500155506 0.026030788623029245 1.4897031805396437 2.6469413162926997e-05 4.577255687067663 -0.8968062880200469 down CPLPCIPT(ph)LIGTPVK ddPTM_PC-9_AZD4547_30min_R2 1 CPLPCIPTLIGTPVK 15 0 Q9H0H5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 CPLPCIPT(0.5)LIGT(0.5)PVK 93.05799999999999 0.0083041 36663000.0 27024.0 22682.0 35693.0 18578.0 26150.0 29472.0 25860.0 28555.0 33447.0 27867.0 True False 35617.06986588104 30013.51292931494 35219.68749860808 14295.12912723877 22519.523881856665 27629.111180978503 28161.489902541933 24142.480878621885 35214.94013659615 26891.38481205467 1.3244788289933989 1.1161014257570219 1.3097015175960762 0.5315876897805075 0.8374252214695087 1.0274335581480776 1.0472309291382387 0.8977775241905531 1.3095249791974364 1.0 14.71485643041072 CPLPCIPTLIGT(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 1 CPLPCIPTLIGTPVK 15 0 Q9H0H5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 CPLPCIPT(0.012)LIGT(0.988)PVK 110.84 0.0011843 27755000.0 22133.0 28361.0 23557.0 9276.2 31855.0 38245.0 37021.0 32519.0 26798.0 28934.0 True False 29170.833605000946 37528.13862041709 23244.61878812964 7137.715405861354 27432.483107324817 35853.53410411653 40315.79728081999 27493.935762280005 28214.487570798698 27921.029466824184 1.0447621080613012 1.344081480412751 0.832512956434824 0.2556394066466066 0.9825025663871076 1.2841050200787818 1.4439223069737916 0.9847035115574212 1.010510289540835 1.0 14.769064515198068 -6.530530452365561 23.306417303068013 1.159164450569831 0.8653578549648224 0.17271789347143307 0.2843875442450911 150.8940355484953 459601.08598950115 0.103502862361746 0.10375524755381522 2.9476067856394834e-07 6.530530452365561 -0.29380659560500866 CPLPCIPTLIGT(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CPLPCIPTLIGTPVK 15 0 Q9H0H5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 CPLPCIPTLIGT(1)PVK 137.79 0.00011020000000000001 2254900.0 10600.0 12664.0 11870.0 10331.0 12463.0 9522.9 11753.0 7918.7 8184.8 7440.1 True False 12394.370640456878 13921.198226539696 12153.025817225685 9752.187563553905 10020.964616394087 9023.502359892658 10639.670755648658 7710.842515556186 8304.48721587968 8788.931234200807 1.4102250103204863 1.583946654670302 1.3827649225350642 1.1095988014566243 1.140180113982347 1.0266893800214356 1.2105761749785886 0.8773356293368868 0.9448802129164482 1.0 13.101472023766254 -5.750121186726304 1.9320135693887475 1.033790114321415 1.5078473672194412 0.8013986532437193 0.09622913167358096 0.14498086670174884 1.103010970855302 0.030653684810286064 0.062148834729069354 1.7777832632893406e-06 5.750121186726304 0.47405725289802625 CPS(ph)PINEHNGLIK ddPTM_PC-9_AZD4547_30min_R2 4 CPSPINEHNGLIK 13 0 A0A087X1M6;G5E9X3;Q9Y2H6-2;Q9Y2H6 A0A087X1M6 FNDC3A Fibronectin type-III domain-containing protein 3A 1 CPS(1)PINEHNGLIK;CPS(1)PINEHNGLIK;CPS(1)PINEHNGLIK;CPS(1)PINEHNGLIK 90.49799999999999 0.0031627 16782500.0 130754.0 129522.0 170727.0 176927.0 179862.0 121482.0 174208.0 169543.0 149211.0 134030.0 True False 172331.05214784655 171387.453559242 168463.04842896006 136139.21364490115 154891.26594411128 113885.71133576351 189712.17451438625 143344.0250605568 157097.9888397061 129337.65049555717 1.3324121126954152 1.3251164908483417 1.3025058657204143 1.0525876504118004 1.1975729058835183 0.8805302315250852 1.4667977482775054 1.1082930957175594 1.2146346267910788 1.0 16.98078278265833 -5.6597768779039646 6.994438395912985 1.1425775755687804 1.3243717109918793 0.2590200275126997 0.14554120451849636 0.31437138870282466 18.88455390037609 0.03838505504533713 0.06676369715121096 2.188885891913526e-06 5.6597768779039646 0.18179413542309897 CPS(ph)PINEHNGLIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 CPSPINEHNGLIK 13 0 A0A087X1M6;G5E9X3;Q9Y2H6-2;Q9Y2H6 A0A087X1M6 FNDC3A Fibronectin type-III domain-containing protein 3A 1 CPS(1)PINEHNGLIK;CPS(1)PINEHNGLIK;CPS(1)PINEHNGLIK 81.71300000000001 0.006418600000000001 10766500.0 108375.0 125470.0 108218.0 110926.0 153404.0 92516.0 102642.0 86784.0 83055.0 85934.0 True False 126720.74699618034 137925.83239765736 110798.32753905053 104711.17584694443 123345.58741982799 87664.29809489001 92919.00669627244 84506.0119552487 84269.52225037708 101513.15394683013 1.248318489469387 1.35869911469699 1.0914676889763835 1.0315035222114106 1.2150699946179695 0.8635757503978865 0.9153395701303982 0.832463662783157 0.8301340168636194 1.0 16.631307156569335 -6.040128089805627 0.6403849978951054 0.8624464749601708 1.335718006944321 0.6860483778478622 0.09924028542823449 0.572399758589978 0.4553309269130598 0.06287432452844752 0.1613810428317647 9.117418926607563e-07 6.040128089805627 0.4732715319841503 CPS(ph)PINEHNGLIK ddPTM_PC-9_Lapatinib_30min_R1 2 CPSPINEHNGLIK 13 0 A0A087X1M6;G5E9X3;Q9Y2H6-2;Q9Y2H6 A0A087X1M6 FNDC3A Fibronectin type-III domain-containing protein 3A 1 CPS(1)PINEHNGLIK;CPS(1)PINEHNGLIK 91.65700000000001 0.0028368 10590600.0 80677.0 99721.0 51952.0 36072.0 55529.0 52631.0 46308.0 50931.0 61017.0 27150.0 True False 79526.53118565005 99490.10215133986 47680.7071005194 38724.85521266446 52262.893394214436 50380.09481885336 48705.601653215825 53297.44019275666 54144.62292250507 31842.841324899022 2.4974696941841525 3.1244103230682843 1.4973760228876374 1.2161243658361651 1.6412760677027984 1.582148223043759 1.5295620499522204 1.6737652161423655 1.7003703397588303 1.0 14.95868145231708 -5.2697414545169545 24.9082745563378 1.5058836226981227 2.8109400212190576 0.8185081060655091 0.25043878956551535 190.69113851033813 572121.6788686601 0.0622918486143249 0.13320849058652104 5.373515989204604e-06 5.2697414545169545 1.305056398520935 CPS(ph)QSSSRPAAMISQPPTPPTGQPVR ddPTM_PC-9_Lapatinib_30min_R1 2 CPSQSSSRPAAMISQPPTPPTGQPVR 26 1 Q6PKG0;Q6PKG0-3 Q6PKG0 LARP1 La-related protein 1 1 CPS(0.738)QS(0.124)S(0.038)S(0.038)RPAAMIS(0.061)QPPT(0.001)PPTGQPVR;CPS(0.243)QS(0.212)S(0.212)S(0.212)RPAAMIS(0.116)QPPT(0.004)PPTGQPVR 65.064 0.00023761 9732400.0 1705.57 3414.9 3706.5 4775.5 5378.9 6072.9 6675.2 6081.9 6864.1 6843.4 True False 1681.2482590367692 3406.9930088608326 3401.7658775037553 5126.706200601 5062.523677324283 5813.176223621332 7020.809193995558 6364.48727706754 6090.9927758225895 8026.272571742687 0.20946812408985155 0.4244801031123089 0.42382885045295116 0.6387406052779834 0.6307440511237327 0.7242684785073475 0.8747284784113905 0.7929567828875346 0.758881874665776 1.0 12.970514435450344 -5.43685963398233 0.3949968423653621 0.9115852347848592 1.4497245915811898e-16 0.915089088156207 0.06563444118524037 0.9492922465517684 0.17163565151534296 0.05895605630181563 0.3909519019426083 3.65712972665322e-06 5.43685963398233 -0.9115852347848591 down CPS(ph)QSSSRPAAMISQPPTPPTGQPVREDAK ddPTM_PC-9_AZD4547_30min_R2 1 CPSQSSSRPAAMISQPPTPPTGQPVREDAK 30 2 Q6PKG0;Q6PKG0-3 Q6PKG0 LARP1 La-related protein 1 1 CPS(0.416)QS(0.124)S(0.124)S(0.32)RPAAMIS(0.015)QPPT(0.001)PPTGQPVREDAK 52.192 0.0063697 19426000.0 20419.0 14853.0 19634.0 26475.0 23624.0 24503.0 17612.0 17046.0 17927.0 23327.0 True False 26911.817258415686 19653.941783754286 19373.640331372288 20371.597784672536 20344.21537992284 22970.82353649279 19179.43388103514 14411.93237811202 18874.58462130413 22510.328830186216 1.195531947197817 0.87310771566333 0.8606555895972675 0.9049889025767738 0.9037724652267793 1.0204570404004518 0.8520281523082699 0.6402364215482141 0.8384855131922118 1.0 14.458299511339915 -7.514916486231799 24.890770644749853 0.7928430429024179 0.9454396278327662 0.1854889673181701 0.12339062100256867 516.939594332109 1616017.811777772 0.054069505545365854 0.033051677970880794 3.0555086235712016e-08 7.514916486231799 0.15259658493034833 CPS(ph)QSSSRPAAMISQPPTPPTGQPVREDAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CPSQSSSRPAAMISQPPTPPTGQPVREDAK 30 2 Q6PKG0;Q6PKG0-3 Q6PKG0 LARP1 La-related protein 1 1 CPS(0.278)QS(0.278)S(0.086)S(0.225)RPAAMIS(0.086)QPPT(0.03)PPT(0.016)GQPVREDAK 42.275 0.044077 7866000.0 6361.8 5662.1 4580.9 6758.5 11489.0 16469.0 16265.0 18679.0 17507.0 13332.0 True False 7438.727088722508 6224.195868484716 4690.126029159991 6379.8431563526365 9237.812924476584 15605.336647982453 14724.2614515975 18188.696042036452 17763.00675500997 15748.986063946068 0.4723305397895983 0.3952124818202538 0.2978049513864915 0.40509548554099756 0.5865655659969488 0.9908788149674937 0.9349339310995738 1.1549121935967408 1.127882562273299 1.0 13.942971328949046 -6.683811791881484 1.9028348762133263 1.0706443242331145 0.38050388899916665 0.9506384204709917 0.07070570924197661 0.06848323285318275 0.5102367120077036 0.029235480138077398 0.028312749188119303 2.0710386704473546e-07 6.683811791881484 -0.6901404352339479 down CPSLDNLAVPES(ph)PGVGGGK ddPTM_PC-9_AZD4547_30min_R2 1 CPSLDNLAVPESPGVGGGK 19 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 CPSLDNLAVPES(1)PGVGGGK 180.86 5.511199999999999e-37 0.0 21286.0 20980.0 20179.0 33409.0 27270.0 25719.0 25941.0 31268.0 27016.0 33246.0 True False 28054.505223695363 27761.37471373897 19911.413275275634 25707.071213904608 23484.031214463917 24110.786864263897 28249.69874562415 26436.249067159835 28444.010605742882 32082.067659294848 0.8744606339475562 0.8653237381255855 0.6206399626960103 0.801290973103996 0.7319986811280258 0.7515346928482178 0.8805448278967026 0.8240194911346588 0.8866015403936116 1.0 14.969479504686516 -8.433388378229246 0.785050743246332 0.9973456306466737 0.7738016036224381 0.46828269712810233 0.07216079914093898 0.6014756492894031 0.8373354449435344 0.07213264775723686 0.027276544270239806 3.6864777902276733e-09 8.433388378229246 -0.2235440270242356 CPSLDNLAVPES(ph)PGVGGGK ddPTM_PC-9_Lapatinib_30min_R1 1 CPSLDNLAVPESPGVGGGK 19 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 CPSLDNLAVPES(1)PGVGGGK 123.58 2.5727e-05 2889000.0 30009.0 24128.0 27627.0 22707.0 39551.0 38590.0 35897.0 30545.0 44890.0 39451.0 True False 29581.066157023375 24072.13309841989 25355.61470330399 24376.94852833144 37224.68794025781 36939.5956576837 37755.57101463005 31964.23221000476 39834.01548734373 46270.05278484679 0.6393134301050771 0.5202529854537662 0.5479919122030443 0.5268407330694632 0.804509303530527 0.7983478175279115 0.8159828818478203 0.6908190132964984 0.8609027457256148 1.0 15.497791124279182 -6.266376754750181 23.942674631324177 0.8108417707013509 0.5551029978689999 0.7357610227917462 0.07878469165305753 118.53341051683601 574799.849284108 0.022958069610706722 0.026878738163516113 5.415309031676065e-07 6.266376754750181 -0.255738772832351 CPT(ph)PDFEDLPER ddPTM_PC-9_AZD4547_30min_R2 1 CPTPDFEDLPER 12 0 H7C4C9;Q3B820-2;Q3B820;Q3B820-3 H7C4C9 FAM161A Protein FAM161A 1 CPT(1)PDFEDLPER 103.76 0.004876 2401200.0 4172.9 3239.8 5665.0 7302.7 5746.3 4124.0 3821.8 6228.4 4901.2 5505.2 True False 5499.795398288005 4287.001992257936 5589.878398554757 5619.175340590291 4948.5254333580515 3866.125628065803 4161.9327961923755 5265.9438943935775 5160.267426001888 5312.464623652467 1.0352624982765049 0.8069704545741526 1.0522194112441092 1.0577341664680964 0.9314933432828778 0.7277461408124605 0.7834278608957458 0.9912430985325028 0.9713509249599598 1.0 12.375165613750173 -4.423504852027545 15.764932661328674 0.922135685020458 5.20593395304604 0.08426632780059573 0.1090629645016105 1164798.4569600758 1986150.5884990694 0.02951292185279057 174450129.69936842 3.7713353157424524e-05 4.423504852027545 4.283798268025582 CPT(ph)PDFEDLPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 CPTPDFEDLPER 12 0 H7C4C9;Q3B820-2;Q3B820;Q3B820-3 H7C4C9 FAM161A Protein FAM161A 1 CPT(1)PDFEDLPER;CPT(1)PDFEDLPER 86.699 0.021957 4224500.0 9602.3 7121.900000000001 9494.0 8350.1 8224.1 5799.7 9722.5 8403.1 6536.799999999999 5457.7 True False 11227.779735930098 7828.915165002611 9720.372966195499 7882.270968389457 6612.6466421958285 5495.5535222116605 8801.514415195616 8182.527528820413 6632.388333589376 6447.137806870574 1.7415138426178665 1.2143241543029384 1.5077036131966512 1.2226000443157106 1.0256716763753482 0.8524020560496115 1.3651816788864095 1.2691721154308926 1.0287337625265873 1.0 12.654443105928365 -1.5228787452837367 0.5593761976789574 1.1101904950135006 28.59573491670185 0.5260828488801168 0.17362356195434533 125.11551752836624 1.1120096051424848 0.08851908503409693 4146.474761894724 0.029999999999765197 1.5228787452837367 27.48554442168835 CPT(ph)PDFEDLPER ddPTM_PC-9_Lapatinib_30min_R1 2 CPTPDFEDLPER 12 0 H7C4C9;Q3B820-2;Q3B820;Q3B820-3 H7C4C9 FAM161A Protein FAM161A 1 CPT(1)PDFEDLPER;CPT(1)PDFEDLPER 105.95 0.0042287 3785400.0 7631.700000000001 8498.3 9050.599999999999 7075.5 8739.6 8873.0 9505.3 11078.1 9550.2 7100.4 True False 7522.870558517622 8478.622708483996 8306.494604326315 7595.8558731760795 8225.553910714703 8493.522473973248 9997.437924209904 11592.828968592368 8474.555907935619 8327.69467931171 0.903355712260502 1.0181236266439058 0.9974542684618276 0.9121198801928078 0.9877348086679075 1.0199128091323402 1.200504858691121 1.3920814120854061 1.017635280144066 1.0 13.023701460321801 -7.144905139982544 3.6708313014085356 1.1849353271705236 0.9684513462908261 0.3917676523915755 0.10807431241631243 0.2167853109506701 5.26691805317587 0.04238024013412552 0.03203142900933323 7.162998496770897e-08 7.144905139982544 -0.21648398087969756 CPT(ph)PVGDGSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CPTPVGDGSSSR 12 0 Q5TGY3 Q5TGY3 AHDC1 AT-hook DNA-binding motif-containing protein 1 1 CPT(0.999)PVGDGSSSR 78.964 0.035753 0.0 7673.2 5888.7 8659.7 10954.0 11468.0 7932.9 6945.1 7868.6 7552.4 6364.8 True False 8972.121207391854 6473.291218937488 8866.180090095135 10340.282893347163 9220.927723726823 7516.8847589276875 6287.209849830303 7662.057587470848 7662.839562262936 7518.687856270925 1.193309441608046 0.8609602290562536 1.1792190684841823 1.3752775871288365 1.2264011886111421 0.9997601845724007 0.8362110477277609 1.0190684510303678 1.0191724551873478 1.0 12.87626519278518 -6.863999947022689 5.982740049046632 0.9636723462903675 1.1616529512867682 0.3584849504524361 0.12868766738835197 0.2680604604566492 13.448948552349972 0.050284837918487285 0.044414308839942754 1.3677289924379398e-07 6.863999947022689 0.1979806049964007 CPT(ph)PVGDGSSSR ddPTM_PC-9_Lapatinib_30min_R1 2 CPTPVGDGSSSR 12 0 Q5TGY3 Q5TGY3 AHDC1 AT-hook DNA-binding motif-containing protein 1 1 CPT(0.998)PVGDGS(0.001)SSR;CPT(0.999)PVGDGS(0.001)SSR 84.169 0.025319 6539500.0 17801.1 21947.0 21812.0 19597.4 22935.0 18953.0 17734.5 21887.0 26212.0 19214.3 True False 17547.253049678064 21896.183069919658 20018.70155675486 21038.658171009953 21586.008391944888 18142.42437160092 18652.705634425052 22903.949922421813 23259.728535403294 22535.466153554575 0.7786505471026297 0.9716321340202638 0.8883198341826739 0.9335798970234069 0.9578682883619904 0.8050609757961128 0.8277044507234618 1.016351282301259 1.032138779686813 1.0 14.459909672534419 -7.778803406148176 24.792109376252615 1.0181838874723876 0.8863426798699049 0.5109577403866854 0.060660511786526296 196.64854446052755 280767.57741595554 0.033680663908984144 0.01624037877757475 1.6641658046028354e-08 7.778803406148176 -0.13184120760248275 CQENGQELS(ph)PIALEPGPEPHR ddPTM_PC-9_AZD4547_30min_R2 1 CQENGQELSPIALEPGPEPHR 21 0 A0A0A0MR08;O94966-2;O94966-7;O94966-6;O94966-5;H0YB23 A0A0A0MR08 USP19 Ubiquitin carboxyl-terminal hydrolase 19 1 CQENGQELS(1)PIALEPGPEPHR 73.655 0.00097521 2197700.0 14594.0 13586.0 19112.0 23038.0 20733.0 19690.0 17408.0 20151.0 15687.0 23872.0 True False 19234.588425942424 17977.408811289686 18858.56239244105 17726.945033551863 17854.580827630383 18458.781187346176 18957.27827623549 17037.12597391385 16516.182794354772 23036.248546071285 0.8349705199383597 0.7803965465703243 0.8186472877614998 0.769523952569747 0.7750646027247953 0.8012928472459213 0.8229325290670454 0.7395790134769772 0.7169649503183331 1.0 14.491618172517002 -10.602560646603836 5.05720041549303 1.000004769461421 0.7848692214241645 0.7716329446179041 0.03519013266208711 1.95412201643994e-06 3.556613915678297e-07 0.03518517566987167 0.008533469384881818 2.497119657113219e-11 10.602560646603836 -0.21513554803725643 CQENGQELS(ph)PIALEPGPEPHR ddPTM_PC-9_Lapatinib_30min_R1 1 CQENGQELSPIALEPGPEPHR 21 0 A0A0A0MR08;O94966-2;O94966-7;O94966-6;O94966-5;H0YB23 A0A0A0MR08 USP19 Ubiquitin carboxyl-terminal hydrolase 19 1 CQENGQELS(1)PIALEPGPEPHR 63.138000000000005 0.0034611999999999993 1544700.0 26940.0 34585.0 41420.0 34711.0 42018.0 40083.0 37768.0 33608.0 36807.0 34082.0 True False 26555.830659809068 34504.92055739604 38014.60748582369 37263.76273250158 39546.58385056643 38368.74352803669 39723.44223975673 35169.55037203603 32661.408065107164 39973.02828858963 0.6643437286784067 0.8632050668836999 0.951006443929469 0.9322226593259781 0.989331695488657 0.9598658187973493 0.9937561385884756 0.8798320236867126 0.8170861569282309 1.0 15.286739252568914 -4.7629937938461815 2.3050673460632183 0.9401726371653092 0.5875855005435732 0.7099876383893005 0.05328621808701417 0.3636876426061129 2.2219747473206946 0.014759799551892707 0.26828481783546615 1.7258625547303488e-05 4.7629937938461815 -0.352587136621736 CQHLQAEK ddPTM_PC-9_AZD4547_30min_R2 2 CQHLQAEK 8 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 113.66 0.0031141 8857200.0 143806.0 111398.0 130180.0 150555.0 154868.0 158933.0 158572.0 128807.0 171906.0 182253.0 False True 189533.3166493818 147405.224993379 128453.72814189909 115846.87080156259 133367.25141626695 148994.89438539845 172684.60080533216 108902.83784040116 180992.60020694518 175872.37794349573 1.0776752942424823 0.838137442144197 0.7303803453613887 0.6586984957852896 0.7583183497929117 0.8471762088374534 0.981874486628095 0.6192151326650593 1.0291132827299037 1.0 17.42416938912185 -8.308833621548423 24.93195856530213 1.014557036315792 0.8116336868515648 0.2722759375211089 0.13115193876151812 611.2669782523706 321554.4679212383 0.12797419441359487 0.03304315684671071 4.9109597925512325e-09 8.308833621548423 -0.2029233494642273 CQHLQAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CQHLQAEK 8 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 91.867 0.0070528000000000006 2960200.0 46003.0 55166.0 50175.0 49348.0 76697.0 56030.0 50493.0 58110.0 56201.0 51309.0 False True 53790.399299333774 60642.51590060716 51371.36228974716 46583.191548374605 61668.773424021274 53091.68816482223 45709.937502337096 56584.67407263439 57022.83330315388 60610.91553817947 0.887470496390219 1.000521364215457 0.8475595828508444 0.7685610939011696 1.017453256999153 0.875942686121928 0.7541535562772338 0.9335723370981106 0.9408013853087994 1.0 15.887290014414171 -8.365873644111007 2.286558239208457 0.9932602217415254 0.8827769464889453 0.17384254058864834 0.08061207165675378 0.5276542140688476 5.394117303360137 0.0782918189898567 0.021929716111389625 4.306518883602663e-09 8.365873644111007 -0.11048327525258006 CQHLQAEK ddPTM_PC-9_Lapatinib_30min_R1 2 CQHLQAEK 8 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 109.44 0.0031708 10410000.0 166361.0 179686.0 163309.0 159005.0 189234.0 145130.0 182137.0 222800.0 218210.0 178643.0 False True 163988.6616331289 179269.94810687503 149882.36441097033 170698.7581251308 178103.62816835844 138923.128214554 191567.1626568147 233152.10137138882 193632.89194683186 209521.20452316492 0.7826828888576675 0.8556172083625776 0.715356542322661 0.8147087475638205 0.8500506121740393 0.6630504465202923 0.9143091893385655 1.1127852281204849 0.9241684744391758 1.0 17.67673673321754 -7.5112832982932884 9.59355479518052 1.0139732252466418 0.7856507558861399 0.6974865463665176 0.0692051389933176 0.11709448093001115 89.32027741740485 0.028869408829801473 0.018153910712458827 3.081177385770936e-08 7.5112832982932884 -0.22832246936050193 CQSVSS(ph)AGELETENYER ddPTM_PC-9_Lapatinib_30min_R1 1 CQSVSSAGELETENYER 17 0 Q96RS0 Q96RS0 TGS1 Trimethylguanosine synthase 1 CQS(0.001)VS(0.049)S(0.925)AGELET(0.025)ENYER 63.614 0.024896 3023800.0 10180.0 9858.5 12492.0 10640.0 12816.0 11398.0 13343.0 10280.0 13236.0 9180.1 True False 10034.831333216634 9835.673248954436 11464.955980514475 11422.501093999505 12062.188077225459 10910.534110035724 14033.83525219959 10757.64632898507 11745.222298740951 10766.868053285645 0.9320102450920609 0.9135129361925223 1.064836675231271 1.0608935706715366 1.1203061110741976 1.0133433470196782 1.3034278104594204 0.999143509119371 1.0908671157307206 1.0 13.39431102858582 -5.325953227539177 3.4847464769344683 1.090280474185431 0.9197354927101642 0.36449482839044445 0.08366943914461532 0.23237867971505327 5.546451684031661 0.021770128879689515 0.053906117896350934 4.721138840442917e-06 5.325953227539177 -0.17054498147526687 CRLT(ph)EGSERLPR ddPTM_PC-9_Lapatinib_30min_R1 1 CRLTEGSERLPR 12 2 A0A3B3ITI3;A0A3B3IS53;A0A3F2YNX6;Q92794 A0A3B3ITI3 KAT6A Histone acetyltransferase KAT6A 1 CRLT(0.5)EGS(0.5)ERLPR 91.31299999999999 0.027246 1973600.0 6936.5 13155.0 21847.0 21009.0 13919.0 16640.0 10590.0 12756.0 18361.0 13099.0 True False 6837.584238001689 13124.540405740792 20050.82399185878 22554.071943969513 13100.311785806896 15928.345989734558 11138.298382732039 13348.690328067472 16292.990830098417 15363.144696679643 0.445064104582668 0.854287365305967 1.3051249850033801 1.4680634980183458 0.852710304071939 1.0367894271787383 0.7250012027250711 0.8688774721331927 1.0605244662975633 1.0 13.907185932454109 CRS(ph)PGMLEPLGSSR ddPTM_PC-9_AZD4547_30min_R2 5 CRSPGMLEPLGSSR 14 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 CRS(1)PGMLEPLGSSR;CRS(1)PGMLEPLGSSR;CRS(1)PGMLEPLGSSR;CRS(1)PGMLEPLGSSR;CRS(1)PGMLEPLGSSR 96.37100000000001 0.0013995999999999998 101061700.0 72058.4 64830.9 77814.8 117054.9 99941.7 104223.6 61470.6 100455.5 71033.3 76286.1 True False 94971.47229217018 85786.220587652 76782.92490871287 90069.70128517717 86066.5200743156 97706.48181602302 66941.36431566878 84932.4107127437 74787.97522064384 73615.34685868165 1.2901042560389695 1.165330657917494 1.0430287730099537 1.2235179908624587 1.1691382809013493 1.327256964551003 0.9093397935647193 1.1537323987046786 1.0159291290743122 1.0 16.167718941060848 -7.263725974063624 24.999960694699492 1.0325613694001488 1.1934612015419945 0.4879555339587126 0.09130187167641071 208.03652108411603 2274501.7598014413 0.0368599635916721 0.026225846430820803 5.4484632502366535e-08 7.263725974063624 0.16089983214184578 CRS(ph)PGMLEPLGSSR ddPTM_PC-9_Lapatinib_30min_R1 7 CRSPGMLEPLGSSR 14 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 CRS(1)PGMLEPLGSSR;CRS(1)PGMLEPLGSSR;CRS(1)PGMLEPLGSSR;CRS(1)PGMLEPLGSSR;CRS(1)PGMLEPLGSSR;CRS(1)PGMLEPLGSSR;CRS(0.998)PGMLEPLGS(0.002)SR 120.29 4.1932e-05 179760000.0 101184.8 112443.4 146277.0 124318.5 139472.7 121722.0 136595.9 121621.0 134692.7 104705.29999999999 True False 99741.88619698008 112183.04421580205 134250.66970554888 133461.2972043586 131269.18999987858 116516.23380784079 143668.16733312805 127271.9556592894 119522.18974898961 122803.47159395767 0.8122073822698649 0.9135168799358423 1.093215590430869 1.086787657319985 1.0689371260929195 0.9488024425978343 1.1699031425443593 1.0363872780413448 0.9732802191796546 1.0 16.905991820003152 -5.0415226180188775 3.364627431798992 1.0511279410854169 0.8213413581865041 0.6099575736245836 0.06125002951096241 0.15247110146850212 3.383909447289262 0.015863506447887376 0.06410230109278088 9.088189666202582e-06 5.0415226180188775 -0.22978658289891274 CS(ph)DS(ph)TLLSNLLEEMKAT(ph)LAK ddPTM_PC-9_Lapatinib_30min_R1 1 CSDSTLLSNLLEEMKATLAK 20 1 A0A2R8Y611;O14617-3;O14617-4;O14617-2;O14617;O14617-5 A0A2R8Y611 AP3D1 AP-3 complex subunit delta-1 3 CS(0.5)DS(0.5)T(0.5)LLS(0.5)NLLEEMKAT(1)LAK 47.09 0.025509999999999998 4826500.0 16440.0 11435.0 7875.1 11538.0 9418.3 12506.0 7877.2 12467.0 10866.0 7457.8 True False 16205.562585273234 11408.522960064309 7227.639676765091 12386.543009639687 8864.334111090233 11971.147532909883 8285.042872564381 13046.2623330211 9642.156655947356 8746.870793106144 1.8527268743978322 1.304297643113232 0.8263114715792491 1.4161113502902267 1.0134291817911234 1.3686205977050623 0.9472007839757103 1.4915348176062608 1.1023549888889217 1.0 13.094551267469384 -4.795511588633342 3.971064099589078 1.163570185621935 1.905075929180434 0.5090213069927767 0.20721586761558597 0.17042051957015714 4.9494153142128186 0.04800456545802688 0.3525607455371785 1.601357917436816e-05 4.795511588633342 0.7415057435584991 CS(ph)EMVPGTADCHITADRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CSEMVPGTADCHITADRK 18 1 P21217;K7ES24;K7ENT3 P21217 FUT3 Galactoside 3(4)-L-fucosyltransferase 1 CS(0.988)EMVPGT(0.012)ADCHITADRK 46.415 0.036012999999999996 14856000.0 12111.0 15544.0 13689.0 17247.0 22278.0 14241.0 19273.0 16731.0 18307.0 9248.1 True False 14161.153096846527 17087.105593282784 14015.397675821601 16280.706505528437 17912.785823961112 13494.176890152286 17447.3219155634 16291.82897795983 18574.705241558666 10924.707322080681 1.296250112643699 1.564079026515141 1.2829082979178867 1.4902647755718246 1.63965818908085 1.235198023372056 1.59705165558984 1.49128287812629 1.700247401961611 1.0 13.415307009331269 CS(ph)LPAEEDSVLEK ddPTM_PC-9_AZD4547_30min_R2 1 CSLPAEEDSVLEK 13 0 E7EVA0;P27816;P27816-6 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 CS(1)LPAEEDSVLEK 145.52 1.6757e-07 0.0 8824.6 8537.1 9521.9 12151.0 12258.0 11506.0 9795.4 13461.0 10308.0 10096.0 True False 11630.639236917335 11296.550622910432 9395.633384501065 9349.774681078603 10556.188288481806 10786.528001097258 10667.171623795793 11380.911753007507 10852.859835800911 9742.542112983238 1.1937992263249195 1.1595074973149226 0.9643923809146413 0.9596853236711987 1.0835147712027107 1.1071574416622505 1.0949063909695975 1.1681665443191591 1.113965914639263 1.0 13.250082547244315 -6.52401425038895 23.44860743901935 1.1059074737063326 1.062453343364582 0.01708029720367321 0.07882168329207735 60.54706270927138 1250226.3889238213 0.02806794812116053 0.028327194429179085 2.99216645383794e-07 6.52401425038895 -0.04345413034175061 CS(ph)LPAEEDSVLEK ddPTM_PC-9_Lapatinib_30min_R1 1 CSLPAEEDSVLEK 13 0 E7EVA0;P27816;P27816-6 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 CS(1)LPAEEDSVLEK 101.61 0.0019593 1556600.0 5179.8 6153.1 6859.5 6973.6 6985.5 5594.6 7351.8 7122.3 6962.3 6229.0 True False 5105.935102141018 6138.852874995337 6295.538388435726 7486.461807247646 6574.6266240214145 5355.331999649579 7732.440231366329 7453.2280592344705 6178.132457730741 7305.674350379221 0.6988999040007827 0.840285589060876 0.8617326870186787 1.024746169648123 0.8999342577704877 0.7330373272621433 1.0584156726017981 1.0201971374275107 0.8456621745547758 1.0 12.834801731824413 -4.611683691402305 1.157843856491199 0.9357014396572603 0.5162036161922651 0.37738571746478733 0.09382037761907631 2.5020776220634575 2.194419719029762 0.02972546371648913 1.3983778601312549 2.4452108184961314e-05 4.611683691402305 -0.4194978234649952 CS(ph)PTVAFVEFPSSPQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 CSPTVAFVEFPSSPQLK 17 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 CS(0.996)PT(0.004)VAFVEFPSSPQLK;CS(0.92)PT(0.08)VAFVEFPSSPQLK 118.21 0.00011574 4475800.0 34559.0 32650.0 26890.3 39718.0 46112.0 43691.0 39703.0 48797.0 35363.0 32094.0 True False 40409.1561286367 35891.27622366718 27531.46673403066 37492.72922749337 37076.68461776172 41399.76704639029 35942.04441517219 47516.13045469525 35880.116974776814 37912.38814403581 1.0658562571979173 0.9466899338366638 0.7261865601669246 0.9889308234831296 0.9779569801010924 1.0919852078192838 0.9480290262544808 1.2533140954923003 0.9463955907621002 1.0 15.210381715906106 -6.398487671641635 2.217496497305732 1.0568558223028799 0.9152549510016558 0.18033128195873172 0.11475760753901423 0.47667820337491706 4.610669309101243 0.039808199166661215 0.046525430513956495 3.9949590167511496e-07 6.398487671641635 -0.14160087130122412 CS(ph)PVNSHLCLSR ddPTM_PC-9_AZD4547_30min_R2 1 CSPVNSHLCLSR 12 0 Q6AWC2-2;Q6AWC2-4;Q6AWC2;Q6AWC2-6;Q6AWC2-5 Q6AWC2-2 WWC2 Protein WWC2 1 CS(1)PVNSHLCLSR 67.415 0.020936 6728900.0 19733.0 23899.0 25658.0 34121.0 31291.0 25354.0 27133.0 31349.0 22634.0 18369.0 True False 26007.683528102094 31623.884379582843 25317.758155360618 26254.930614194953 26946.784771976185 23768.610371964183 29547.78443641417 26504.73237835468 23830.38703177318 17725.90690108845 1.4672131402487005 1.7840488814505169 1.4282912742707679 1.481161486444611 1.520192164064764 1.3408967171380488 1.666926527443276 1.4952539537893643 1.3443818228736095 1.0 14.113571820736796 -8.633969859647266 2.0903469314093654 1.0009728926905073 1.5267181750447891 0.6523127780474576 0.11686940469133483 0.2861760189580909 2.6755299917936157 0.11120104286747787 0.030731886177193496 2.322898001572994e-09 8.633969859647266 0.5257452823542819 CS(ph)QTQCPR ddPTM_PC-9_AZD4547_30min_R2 1 CSQTQCPR 8 0 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BVD2;H3BT57;H3BUJ5;H3BRN3;P29590-2 P29590;P29590-2 PML Protein PML 1 CS(0.999)QT(0.001)QCPR 89.82700000000001 0.026817 0.0 6454.6 5528.6 7899.9 10247.0 9267.2 6680.3 5037.1 10670.0 5410.5 7772.9 True False 8507.028535979718 7315.611832334472 7795.142164297039 7884.712464571836 7980.609243515958 6262.579784958287 5485.392141844314 9021.196672207865 5696.487984245331 7500.773136886623 1.1341535573372594 0.9753143707757828 1.039245158070812 1.0511866337880704 1.0639715530482639 0.834924569863437 0.7313102318571334 1.202702242498742 0.7594534430366462 1.0 12.872823592706034 -6.7466760639605114 24.980608308001095 0.9074489940732372 1.0476311403399938 0.24416395260287738 0.12922590631354466 366.4756126083624 620102.3391542347 0.04162681748999755 0.04146076922055873 1.7919419477928204e-07 6.7466760639605114 0.14018214626675662 CS(ph)TVVCVICLEKPKY(ph)RCPACR ddPTM_PC-9_AZD4547_30min_R2 2 CSTVVCVICLEKPKYRCPACR 21 3 A0A087WTR0;A0A087X045;Q15649-2;Q15649 A0A087WTR0 ZNHIT3 Zinc finger HIT domain-containing protein 3 2 CS(0.5)T(0.5)VVCVICLEKPKY(1)RCPACR;CS(0.5)T(0.5)VVCVICLEKPKY(1)RCPACR 49.606 0.036377 17178800.0 19538.9 21888.1 30141.0 50489.0 39309.0 30526.0 27460.0 33813.0 29211.0 32115.0 True False 25751.863765632876 28963.000279875596 29741.310646220467 38849.54109727408 33851.62387273054 28617.204394359043 29903.886802931236 28587.97779544185 30755.033824561557 30990.663625045214 0.8309555444569898 0.9345717997619465 0.9596861495468242 1.2535885506458688 1.0923168436242594 0.9234137332648775 0.9649321216459625 0.9224706557215631 0.992396748797169 1.0 14.919546028255793 -5.000107260303919 2.263594627619637 1.0172086679104797 0.8274144057374723 0.2783191664168069 0.09263105347126503 0.5907653378857944 4.943813452963154 0.02786180111455533 0.18764514060375012 9.997530545191827e-06 5.000107260303919 -0.18979426217300743 CS(ph)VKNDHSAY(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CSVKNDHSAYK 11 1 A0A0G2JR96;A0A0G2JQT1;Q7L576;A0A087WTQ3;A0A087WWZ1;E7EVJ5;Q96F07-2;Q96F07 A0A0G2JR96 CYFIP1;CYFIP2 Cytoplasmic FMR1-interacting protein 1;Cytoplasmic FMR1-interacting protein 2 2 CS(0.998)VKNDHS(0.002)AY(1)K 104.2 0.027863 9672600.0 11742.0 16421.0 22357.0 18691.0 16074.0 18179.0 14741.0 14191.0 9696.8 13599.0 True False 13729.688684928738 18051.16835739169 22890.075669394646 17643.8038670396 12924.415088174475 17225.6612376995 13344.625764402024 13818.501286607381 9838.597355456708 16064.39105037524 0.85466599025601 1.1236758555482276 1.424895322680779 1.0983176275846118 0.804538127069098 1.072288466066514 0.8306960234319193 0.8601945285865412 0.6124475757969607 1.0 13.97157867344594 -6.176349344800423 5.3809782535128035 0.8655709902136456 1.151613525011629 0.3572083095809787 0.17164173297139906 0.25128247310496005 12.075081613083157 0.05265032444891924 0.06839517306614547 6.662706081010353e-07 6.176349344800423 0.28604253479798347 CS(ph)VSAVNLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CSVSAVNLPK 10 0 Q3KQU3-4;Q3KQU3;C9JIR3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 CS(0.587)VS(0.413)AVNLPK 67.214 0.044179 6488700.0 27879.0 34975.0 39260.0 49275.0 52459.0 49550.0 51844.0 55464.0 48465.0 40147.0 True False 32598.364064650697 38447.08685827747 40196.107294379115 46514.281501705445 42180.035530082445 46951.510772210255 46932.96100194414 54008.12876896567 49173.70893822806 47425.33329652286 0.6873618338290255 0.8106866981385313 0.8475661529473367 0.9807897650582413 0.8893988212239935 0.9900090839351603 0.9896179476167262 1.1388033570852194 1.0368658588179787 1.0 15.533370292217324 -4.088560107519492 0.3783599444284676 1.0624747048808099 0.17775016530543636 0.8243033067168161 0.051456517543846995 3.991757518346381 0.3028952746883927 0.04390640224973224 1.7779889597764615 8.155299077980448e-05 4.088560107519492 -0.8847245395753736 CSATPSAQVKPIVS(ph)ASPPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CSATPSAQVKPIVSASPPSR 20 1 H0Y3K4;Q96EV2 H0Y3K4 RBM33 RNA-binding protein 33 1 CSATPSAQVKPIVS(0.45)AS(0.45)PPS(0.1)R 95.223 0.0002566 35460000.0 43696.0 43494.0 45934.0 55733.0 57553.0 43200.0 47257.0 45065.0 50056.0 42761.0 True False 51092.86976466071 47811.79687816788 47029.24076566509 52610.46069882394 46275.90279766742 40934.51595074638 42780.47484894827 43882.09150031437 50787.97430335172 50513.23080411027 1.0114749928152145 0.9465202703739437 0.9310281686008948 1.0415184271789444 0.9161144924015024 0.8103721599097465 0.8469162270544615 0.8687247044341434 1.005439040324047 1.0 15.624373698412308 -6.507481799756684 24.732552724324137 0.8909157787298724 0.9766754424734421 0.22299993259132767 0.06506861994920694 825.6267053903417 1326229.872501299 0.020587775436886314 0.022608033439004267 3.1082661600128097e-07 6.507481799756684 0.08575966374356969 CSATPSAQVKPIVSAS(ph)PPSR ddPTM_PC-9_AZD4547_30min_R2 2 CSATPSAQVKPIVSASPPSR 20 1 H0Y3K4;Q96EV2 H0Y3K4 RBM33 RNA-binding protein 33 1 CSATPSAQVKPIVS(0.083)AS(0.842)PPS(0.075)R;CSATPSAQVKPIVS(0.321)AS(0.65)PPS(0.029)R 98.21 0.00019463 102302000.0 92939.0 70630.0 91530.0 136393.0 121991.0 116042.0 116850.0 128889.0 106299.0 125603.0 True False 122491.66874870934 93459.76625507069 90316.25239536037 104949.70110084381 105054.65536793771 108785.87539573517 127249.4236315555 108972.1666245737 111917.74812629049 121205.67720057783 1.010609994332224 0.7710840648199038 0.7451486966728469 0.8658810669995867 0.8667469857380317 0.8975311875508134 1.0498635589566991 0.8990681718995766 0.9233705112763227 1.0 16.887097749793043 -6.8778347719320765 2.78853800083634 0.9608326671728011 0.8401855903345411 0.3253717177830169 0.07706288187754798 0.3227567294832302 5.074142611022165 0.030213773948196788 0.026221172063984336 1.324845479021822e-07 6.8778347719320765 -0.12064707683826004 CSATPSAQVKPIVSAS(ph)PPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CSATPSAQVKPIVSASPPSR 20 1 H0Y3K4;Q96EV2 H0Y3K4 RBM33 RNA-binding protein 33 1 CSATPS(0.001)AQVKPIVS(0.145)AS(0.803)PPS(0.05)R 61.684 0.0053622 29846000.0 32967.0 31272.0 30874.0 50115.0 52974.0 34248.0 46395.0 32275.0 35053.0 28734.0 True False 38547.66197206999 34376.47749055192 31610.153250297022 47307.21902502219 42594.12497704086 32451.974589841695 42000.12972928782 31427.81544818922 35565.58381123919 33943.24674178117 1.1356504068487114 1.0127633856615572 0.93126486958561 1.3937152030536648 1.2548630159356917 0.9560657186602055 1.2373633568055036 0.9258930262998184 1.0477955771821044 1.0 15.050836947795956 -7.773454003452859 24.995245523903932 0.9901332321822658 1.1274511651449814 0.18020426373101261 0.13705572358248955 441.69046740458595 918879.4638802136 0.07741322876854066 0.03763384719966167 1.6847908551483515e-08 7.773454003452859 0.13731793296271566 CSATPSAQVKPIVSAS(ph)PPSR ddPTM_PC-9_Lapatinib_30min_R1 2 CSATPSAQVKPIVSASPPSR 20 1 H0Y3K4;Q96EV2 H0Y3K4 RBM33 RNA-binding protein 33 1 CSATPSAQVKPIVS(0.023)AS(0.698)PPS(0.279)R;CSATPSAQVKPIVS(0.061)AS(0.809)PPS(0.13)R 100.39 0.00014938 80993000.0 118197.0 103688.0 97676.0 112970.0 117163.0 124991.0 115071.0 109209.0 117021.0 90837.0 True False 116511.48910532486 103447.91680657164 89645.4563202637 121278.19065687254 110271.70269132065 119645.42629825194 121028.8133332728 114283.2488270557 103840.8626942402 106538.05441730589 1.0936138241172808 0.9709949874001801 0.8414407115895465 1.138355598102346 1.035045207972263 1.1230299535000416 1.13601486337649 1.0726988534952229 0.9746833022452158 1.0 16.701009314398824 -5.785814360651928 24.99865446709645 1.075261329375167 0.9689141624101318 0.25851984705340236 0.07691665148336171 285.65331146357215 292961.1778941248 0.021874280803586436 0.03246218095937253 1.63751632885315e-06 5.785814360651928 -0.1063471669650351 CSDAAGYPHATHDLEGPPLDAYS(ph)IQGQHTISPLDLAK ddPTM_PC-9_AZD4547_30min_R2 1 CSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAK 37 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 CSDAAGYPHATHDLEGPPLDAY(0.331)S(0.363)IQGQHT(0.104)IS(0.201)PLDLAK 41.086000000000006 0.026504000000000003 6534400.0 5204.2 4628.5 15592.0 32186.0 21322.0 22018.0 13644.0 23294.0 15810.0 18951.0 True False 6859.02734591541 6124.572109749328 15385.239892368172 24766.01496874295 18361.808344510435 20641.210979328996 14858.289568069691 19694.44754286879 16645.684323245303 18287.531258235475 0.37506578931076684 0.33490425926086836 0.8412967105901565 1.354256876941222 1.0040616245695553 1.1287040709791587 0.8124819779257255 1.0769330898067357 0.9102204167524912 1.0 14.158572709863328 -5.3645536702192915 3.792860710977414 1.0399872732512294 0.3512460259654517 0.7951387342060707 0.1368563888556008 0.0929496312849875 2.387260001054433 0.036588544287128905 0.08443175424189664 4.319627822522491e-06 5.3645536702192915 -0.6887412472857777 down CSDAAGYPHATHDLEGPPLDAYSIQGQHT(ph)ISPLDLAK ddPTM_PC-9_AZD4547_30min_R2 2 CSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAK 37 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 CSDAAGYPHATHDLEGPPLDAY(0.006)S(0.148)IQGQHT(0.811)IS(0.035)PLDLAK;CSDAAGYPHATHDLEGPPLDAY(0.001)S(0.013)IQGQHT(0.76)IS(0.227)PLDLAK 73.805 7.7531e-08 8539100.0 6508.799999999999 6459.5 25261.0 42956.0 31852.0 30005.0 17407.2 28534.0 21392.0 30951.0 True False 8578.463008549683 8547.4070525928 24926.022634755813 33053.157863584245 27429.89960554108 28128.78260672025 18956.407077785305 24124.72594608989 22522.737447366446 29867.414910751195 0.2872181283242476 0.28617833442009877 0.8345557427463648 1.1066628284487485 0.9183888089245816 0.9417883231867817 0.634685229184722 0.8077272846739024 0.7540906206535829 1.0 14.866284754230868 -5.271649823024005 5.75974832137788 0.8731675014414934 0.28169538613423245 0.7834407374117942 0.1237743340625804 0.06938916215431887 9.36384353674766 0.03500227617846616 0.08186565550797074 5.349955590244051e-06 5.271649823024005 -0.5914721153072608 down CSDAAGYPHATHDLEGPPLDAYSIQGQHT(ph)ISPLDLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAK 37 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 CSDAAGYPHATHDLEGPPLDAY(0.052)S(0.208)IQGQHT(0.605)IS(0.135)PLDLAK 66.67699999999999 2.6456e-06 5032400.0 9047.5 11124.0 19460.0 25825.0 34493.0 29787.0 25732.0 18357.0 24795.0 13547.0 True False 10579.063053729586 12228.317204045139 19924.000202460975 24378.108975779644 27734.344260072306 28224.9172829834 23294.478676452945 17875.14820084923 25157.57996746856 16002.96386200701 0.6610689835303304 0.7641282770797637 1.2450193835507548 1.5233496236066775 1.7330754789690568 1.7637306143015667 1.4556352733981286 1.1169898498169464 1.5720575378662027 1.0 13.966051506726272 -5.340012250610036 2.481672079044931 1.4804674737579968 0.6686702451536779 0.6195918094964381 0.22828157049736397 0.19156484130492982 2.2493990118999108 0.06562199316540936 0.1919348900443414 4.570752962201398e-06 5.340012250610036 -0.8117972286043189 CSDAAGYPHATHDLEGPPLDAYSIQGQHT(ph)ISPLDLAK ddPTM_PC-9_Lapatinib_30min_R1 1 CSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAK 37 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 CSDAAGYPHATHDLEGPPLDAY(0.232)S(0.327)IQGQHT(0.415)IS(0.026)PLDLAK 47.303999999999995 0.0032109 5463000.0 17431.0 13614.0 37263.0 18639.0 21045.0 32925.0 19412.0 20617.0 38382.0 17026.0 True False 17182.430743546098 13582.477619441675 34199.379979339654 20009.77423788127 19807.17447606194 31516.87450192371 20417.05837635452 21574.941086058876 34059.01497962189 19968.921414281038 0.8604586290403174 0.6801808338896055 1.7126303053544754 1.0020458202399962 0.9919000663649554 1.5782962859167746 1.022441720951087 1.0804259598432429 1.705601132531081 1.0 14.28546878983302 -5.224841836981929 24.961737860956738 1.2483977529530903 0.7703195015927659 0.32020258386411515 0.28584655614669824 667.8530074846187 455514.1337186666 0.06983742960955211 0.18476073321289252 5.958791135426128e-06 5.224841836981929 -0.47807825136032445 CSDVSELS(ph)SSPPGPYHQEPYVCKPEER ddPTM_PC-9_AZD4547_30min_R2 2 CSDVSELSSSPPGPYHQEPYVCKPEER 27 1 Q9Y478;F5H610;F5H2X8 Q9Y478 PRKAB1 5-AMP-activated protein kinase subunit beta-1 1 CSDVS(0.011)ELS(0.369)S(0.31)S(0.31)PPGPYHQEPYVCKPEER;CSDVS(0.008)ELS(0.309)S(0.278)S(0.278)PPGPY(0.125)HQEPYVCKPEER 110.9 1.0277e-10 27108600.0 45947.0 38135.0 58891.0 79321.0 70231.0 65360.0 65442.0 70403.0 52376.0 57958.0 True False 60557.19024302975 50461.39297942972 58110.066861304156 61034.76894723363 60480.63792530311 61273.02886769663 71266.2112220475 59523.83404999542 55144.48843227679 55928.908061042224 1.0827529508878682 0.9022416980563054 1.0389987731904466 1.0912919823254683 1.0813842075960614 1.095552031890587 1.2742285464301528 1.064276706153991 0.9859747015280667 1.0 15.771306543409553 -5.588146089122135 4.034206292488165 1.095216255033412 0.9876537512928424 0.15231289918603874 0.08413743466459069 0.3282799556805055 10.662377436354191 0.023654507317780224 0.0440548878903366 2.5813917092269573e-06 5.588146089122135 -0.10756250374056953 CSDVSELS(ph)SSPPGPYHQEPYVCKPEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 CSDVSELSSSPPGPYHQEPYVCKPEER 27 1 Q9Y478;F5H610;F5H2X8 Q9Y478 PRKAB1 5-AMP-activated protein kinase subunit beta-1 1 CS(0.001)DVS(0.036)ELS(0.309)S(0.271)S(0.271)PPGPY(0.111)HQEPY(0.001)VCKPEER;CSDVS(0.007)ELS(0.315)S(0.244)S(0.244)PPGPY(0.189)HQEPYVCKPEER;CS(0.002)DVS(0.137)ELS(0.334)S(0.26)S(0.26)PPGPY(0.007)HQEPYVCKPEER 109.23 1.6179e-10 34574000.0 56103.3 52125.6 54937.1 82859.0 83005.0 71213.0 75030.0 70698.0 68862.0 56246.8 True False 65600.48059931544 57300.28508191076 56247.00881411198 78216.67886250267 66740.76610637813 67478.46491667828 67922.61522984099 68842.25241072301 69868.9764758951 66443.89959057611 0.9873062990514138 0.8623859441572841 0.8465338302041745 1.177183749666558 1.0044679273436883 1.0155705088424536 1.0222551001427769 1.0360959069971123 1.0515484025835953 1.0 16.01984912706542 -5.737716490583412 24.99966574961167 1.0416564785400348 0.8951063828744743 0.5606685937118722 0.05882377863629223 167.66877081459515 176691.40869925375 0.01567038093608655 0.02712192265288271 1.8292939979040138e-06 5.737716490583412 -0.14655009566556054 CSDVSELS(ph)SSPPGPYHQEPYVCKPEER ddPTM_PC-9_Lapatinib_30min_R1 1 CSDVSELSSSPPGPYHQEPYVCKPEER 27 1 Q9Y478;F5H610;F5H2X8 Q9Y478 PRKAB1 5-AMP-activated protein kinase subunit beta-1 1 CS(0.001)DVS(0.019)ELS(0.7)S(0.14)S(0.14)PPGPY(0.001)HQEPYVCKPEER 80.453 1.0426e-05 14002000.0 9818.7 9884.8 12205.0 12715.0 17192.0 14558.0 14391.0 12754.0 14384.0 11695.0 True False 9678.683537470943 9861.9123529203 11201.552012662445 13650.103515996585 16180.800360772479 13935.388276355518 15136.095564296207 13346.597400766108 12763.922449765028 13716.46516739204 0.7056252044061572 0.7189835159837599 0.8166500534913134 0.9951618984493749 1.1796625561546912 1.0159606069269158 1.1034982686559096 0.9730347606243908 0.9305547962975564 1.0 13.743621115977783 -5.666939064180147 2.688039717707748 1.0391352104651788 0.7177050447666886 0.8022986290687866 0.06543937931003706 0.11623683373639374 1.6916342640818736 0.020007097082343123 0.03884191316456369 2.153083812528493e-06 5.666939064180147 -0.32143016569849014 CSDVSELSS(ph)SPPGPYHQEPYVCKPEER ddPTM_PC-9_AZD4547_30min_R2 1 CSDVSELSSSPPGPYHQEPYVCKPEER 27 1 Q9Y478;F5H610;F5H2X8 Q9Y478 PRKAB1 5-AMP-activated protein kinase subunit beta-1 1 CS(0.001)DVS(0.158)ELS(0.082)S(0.271)S(0.271)PPGPY(0.216)HQEPYVCKPEER 85.11 4.2155e-07 18191000.0 29443.0 33345.0 38737.0 46264.0 44196.0 46142.0 38577.0 47488.0 33476.0 42793.0 True False 38805.26154755533 44123.11915298501 38223.322069693844 35598.5495716748 38060.148278490924 43256.73344573528 42010.27826644858 40149.820765680124 35245.47301739151 41294.8300951755 0.9397123431218324 1.068490148798068 0.9256200347984843 0.8620582646696444 0.9216686009064731 1.0475096603143303 1.0173253690504145 0.9722723322300544 0.8535081252582574 1.0 15.333673554343758 -12.207659195568917 2.148706847514518 2.1852985326416365 0.9599835101227655 0.03290486027029771 0.06845420889467121 3538394.7448520083 718334.0576807312 21056634.326796994 0.01813322467635493 6.199273605933441e-13 12.207659195568917 -1.225315022518871 CSDVSELSS(ph)SPPGPYHQEPYVCKPEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 CSDVSELSSSPPGPYHQEPYVCKPEER 27 1 Q9Y478;F5H610;F5H2X8 Q9Y478 PRKAB1 5-AMP-activated protein kinase subunit beta-1 1 CSDVSELS(0.054)S(0.469)S(0.469)PPGPY(0.006)HQEPYVCKPEER;CSDVS(0.009)ELS(0.255)S(0.361)S(0.361)PPGPY(0.014)HQEPYVCKPEER;CSDVS(0.004)ELS(0.12)S(0.428)S(0.428)PPGPY(0.019)HQEPYVCKPEER 96.34100000000001 1.1669000000000002e-09 107422000.0 63503.0 71723.0 73613.0 97570.0 101174.0 87962.0 100684.0 79826.0 77640.0 71342.0 True False 74252.80365857852 78843.18543920635 75368.21309885728 92103.46922620777 81349.68098363612 83349.11787174881 91146.48263096502 77730.65208263845 78775.33811955056 84275.73985703863 0.8810697335263677 0.9355383360971046 0.8943049711187151 1.092882357158154 0.9652799384690525 0.9890048786654179 1.0815269351011525 0.9223372255704554 0.9347332726260406 1.0 16.362829767239745 -5.702386118634295 24.999999468882 0.9964777910999716 0.9068273282430984 0.3952216795745819 0.05340657395687845 83.79998583322632 35475.440451563336 0.014674570941741362 0.02541709341617147 1.984329922659423e-06 5.702386118634295 -0.08965046285687317 CSDVSELSS(ph)SPPGPYHQEPYVCKPEER ddPTM_PC-9_Lapatinib_30min_R1 6 CSDVSELSSSPPGPYHQEPYVCKPEER 27 1 Q9Y478;F5H610;F5H2X8 Q9Y478 PRKAB1 5-AMP-activated protein kinase subunit beta-1 1 CS(0.002)DVS(0.005)ELS(0.093)S(0.449)S(0.449)PPGPY(0.002)HQEPYVCKPEER;CS(0.001)DVS(0.005)ELS(0.199)S(0.385)S(0.385)PPGPY(0.024)HQEPY(0.001)VCKPEER;CS(0.013)DVS(0.072)ELS(0.139)S(0.366)S(0.366)PPGPY(0.042)HQEPY(0.001)VCKPEER;CSDVS(0.001)ELS(0.034)S(0.482)S(0.482)PPGPY(0.001)HQEPYVCKPEER;CS(0.002)DVS(0.024)ELS(0.055)S(0.407)S(0.407)PPGPY(0.104)HQEPY(0.002)VCKPEER;CSDVS(0.009)ELS(0.076)S(0.351)S(0.351)PPGPY(0.213)HQEPYVCKPEER 91.565 9.9629e-08 218349000.0 107405.0 127378.0 139830.0 124966.0 135867.0 136274.0 121142.0 138042.0 144526.0 114701.0 True False 105873.38500433502 127083.06406708092 128333.717159409 134156.41651435517 127875.57018479952 130445.87869020959 127414.14000764175 144455.9352670967 128247.9599537501 134526.91502052473 0.7870052248517105 0.9446664561340152 0.9539631317631061 0.9972459153908864 0.9505575160575829 0.9696637930804219 0.9471274948080257 1.0738069422394554 0.9533256592867186 1.0 17.037535318460122 -4.036328384964745 1.2379983235341159 0.9837919597037148 2.399584782567329e-19 0.7239820068500102 0.03581787393169597 4.043016088744942 1.3890737974873468 0.010428250960883957 7.95964329026951 9.197538513001246e-05 4.036328384964745 -0.9837919597037148 CSDVSELSSSPPGPY(ph)HQEPYVCKPEER ddPTM_PC-9_AZD4547_30min_R2 1 CSDVSELSSSPPGPYHQEPYVCKPEER 27 1 Q9Y478;F5H610;F5H2X8 Q9Y478 PRKAB1 5-AMP-activated protein kinase subunit beta-1 1 CSDVS(0.005)ELS(0.05)S(0.188)S(0.188)PPGPY(0.569)HQEPYVCKPEER 101.16 6.816300000000001e-09 10179000.0 35086.0 34398.0 53587.0 62584.0 61870.0 61351.0 49254.0 57184.0 50441.0 60890.0 True False 46242.618165863736 45516.480810447705 52876.40136687619 48156.22571316132 53280.418453937746 57514.712271451215 53637.51058235887 48347.526757594635 53107.208282657535 58758.259633473564 0.7869977506876347 0.7746397033263687 0.8998973369312222 0.8195652154021178 0.9067732568373215 0.978836211797636 0.9128505663194031 0.8228209456709621 0.9038254130386679 1.0 15.842504044753705 -5.34169488175817 0.90782898192138 0.9123527547186057 0.7509151139556076 0.47293544499586226 0.05314950758594891 1.0643661289113786 1.2003622921257524 0.02099501262080167 0.1438974912758778 4.553078292024467e-06 5.34169488175817 -0.16143764076299805 CSEGSFLLTTFPR ddPTM_PC-9_Lapatinib_30min_R1 1 CSEGSFLLTTFPR 13 0 Q15233;Q15233-2;H7C367 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 103.31 0.0067439 0.0 8245.8 10444.0 8293.2 5417.8 7792.8 5439.6 6409.0 7273.6 6139.0 5686.0 False True 8128.213379905479 10419.817559677453 7611.365108677772 5816.243085250989 7334.442825234275 5206.960988326929 6740.826660522162 7611.558009582274 5447.561173464093 6668.817523881242 1.2188387747600073 1.5624685369428333 1.141336538512448 0.8721550806305379 1.0998115931301777 0.7807922423549063 1.0107978867892324 1.1413654643158326 0.8168706302063609 1.0 12.70321525841552 -5.495054787739848 5.17924564842824 0.9681555304198615 1.3873530647115124 0.6238888015932565 0.1330551674057003 0.10952091542548552 8.060908021144396 0.03371374171334494 0.06806279226627304 3.198491583544973e-06 5.495054787739848 0.41919753429165096 CSGPGLS(ph)PGMVR ddPTM_PC-9_AZD4547_30min_R2 5 CSGPGLSPGMVR 12 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 CSGPGLS(1)PGMVR;CSGPGLS(1)PGMVR;CSGPGLS(1)PGMVR;CS(0.001)GPGLS(0.999)PGMVR;CSGPGLS(1)PGMVR 166.62 6.5367e-05 336511000.0 593651.0 585419.0 703760.0 1057610.0 857937.0 815368.0 688259.0 791480.0 630548.0 743650.0 True False 782419.669292118 774644.2432575009 694427.682571384 813794.3544116147 738827.2566205905 764382.9100642 749512.7176656462 669174.9524010373 663877.4799907448 717615.0398494442 1.090305561957383 1.0794704684840795 0.9676883064171496 1.134026336156986 1.029559325812899 1.0651712514617417 1.0444495670309448 0.9324985058025406 0.9251164525899939 1.0 19.452850601161146 -7.710767087874 5.603877876344352 0.9465002044112324 1.0588228405024334 0.5429826573101485 0.04460820209392098 0.1339647046941515 9.170970785114053 0.021215019887016476 0.011727023535892504 1.9464036580236243e-08 7.710767087874 0.11232263609120097 CSGPGLS(ph)PGMVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 CSGPGLSPGMVR 12 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 CSGPGLS(1)PGMVR;CSGPGLS(1)PGMVR;CSGPGLS(1)PGMVR;CS(0.004)GPGLS(0.996)PGMVR 126.09 0.00027392 479179000.0 425606.0 398495.0 384976.0 486773.0 540917.0 394955.0 461465.0 447736.0 418617.0 354688.0 True False 497652.68969832885 438054.950038293 394155.28786960954 459500.6869493579 434928.19685517385 374242.86452145956 417751.6944827208 435983.4044155059 424738.4816794426 418990.1266913367 1.1877432378375388 1.0455018439157662 0.9407269115913498 1.096686193008707 1.0380392499691968 0.893202108309245 0.9970442448885479 1.0405577044460712 1.013719547602468 1.0 18.676556722320214 -4.799345858649587 3.575315709662767 1.0038458893169193 1.2053445996888845 0.5266722097886813 0.052603902496913574 0.21651362701605426 4.679106770797444 0.013746988141599999 0.11438063971784246 1.587282182855788e-05 4.799345858649587 0.2014987103719652 CSGPGLS(ph)PGMVR ddPTM_PC-9_Lapatinib_30min_R1 10 CSGPGLSPGMVR 12 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 CSGPGLS(1)PGMVR;CSGPGLS(1)PGMVR;CS(0.011)GPGLS(0.989)PGMVR;CSGPGLS(1)PGMVR;CS(0.02)GPGLS(0.98)PGMVR;CSGPGLS(1)PGMVR;CSGPGLS(1)PGMVR;CSGPGLS(1)PGMVR;CSGPGLS(1)PGMVR;CSGPGLS(1)PGMVR 121.21 0.00045738 716957300.0 816028.0 903288.0 1049114.0 981654.0 1010436.0 1038502.0 977837.0 1012153.0 1074786.0 835536.0 True False 804391.2910787924 901196.4921338471 962859.8966171513 1053848.1098617464 951004.1410736102 994087.6903264025 1028464.615266814 1059181.3234261894 953732.2826816707 979957.284318264 0.8208432183229198 0.9196283415157129 0.9825529255461304 1.0754020881582473 0.9704546884767575 1.0144194101459931 1.0494994340312451 1.08084438003136 0.9732386277889271 1.0 19.902359338924555 -4.9576888434975945 1.5546056467360887 1.0257061197832018 0.7833707261884915 0.7512637393916262 0.03666636419080453 0.36086996092917467 1.0724169137463642 0.01051146123249182 0.12151889566710362 1.1023288059474471e-05 4.9576888434975945 -0.24233539359471035 CSKT(ph)LYR ddPTM_PC-9_AZD4547_30min_R2 1 CSKTLYR 7 1 A0A0A0MRA3;A0A0A0MTS7;Q8WZ42-3;Q8WZ42-10;Q8WZ42-9;Q8WZ42-5;Q8WZ42-11;Q8WZ42-4;Q8WZ42-7;Q8WZ42-2;Q8WZ42;Q8WZ42-8;Q8WZ42-13;Q8WZ42-12 A0A0A0MRA3 TTN Titin 1 CS(0.019)KT(0.981)LYR 75.189 0.023847 2415800.0 13590.0 8907.9 14747.0 19580.0 14924.0 12975.0 11294.0 12291.0 10177.0 12331.0 True False 17911.33731043974 11787.204471521229 14551.445144481373 15066.133507984434 12852.060206991551 12163.671198873362 12299.144120622921 10391.70836908219 10714.935443242717 11899.295443264291 1.5052435159577975 0.9905800328870301 1.2228829188973838 1.266136602777836 1.0800690064609315 1.0222177654861677 1.0336027186874301 0.8733045093829076 0.9004680566451527 1.0 13.53858853370449 -6.7261483103289486 0.9315787324537051 0.9209642752348495 1.2430901007159292 0.5348430815036506 0.12386644784551316 0.4542553211829804 0.854810203511395 0.07170508783037881 0.06850669112363227 1.8786751450323232e-07 6.7261483103289486 0.3221258254810797 CSKT(ph)LYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CSKTLYR 7 1 A0A0A0MRA3;A0A0A0MTS7;Q8WZ42-3;Q8WZ42-10;Q8WZ42-9;Q8WZ42-5;Q8WZ42-11;Q8WZ42-4;Q8WZ42-7;Q8WZ42-2;Q8WZ42;Q8WZ42-8;Q8WZ42-13;Q8WZ42-12 A0A0A0MRA3 TTN Titin 1 CS(0.007)KT(0.993)LYR 64.567 0.042575999999999996 2186300.0 8887.3 7789.4 9529.6 10519.0 12442.0 12165.0 8320.8 10465.0 10162.0 8820.3 True False 10391.744357823813 8562.680153648798 9756.82180520925 9929.654533058136 10004.079415644324 11527.045984741422 7532.593586624813 10190.304838584048 10310.600025384781 10419.350568543616 0.9973504864302054 0.8218055527855862 0.9364136220414195 0.9530012900262815 0.9601442383412062 1.1063113683440096 0.7229427148142972 0.9780172738739529 0.9895626370911105 1.0 13.346977737709048 -5.52719468387085 0.008858161996738006 1.8580331716472511 2.7154063471953975e-07 0.030981553539759954 0.09828708436423846 27293.191581798772 49.0965754538763 4898.62014557473 5405.511641344963 2.970334203180263e-06 5.52719468387085 -1.8580329001066165 CSKT(ph)LYR ddPTM_PC-9_Lapatinib_30min_R1 1 CSKTLYR 7 1 A0A0A0MRA3;A0A0A0MTS7;Q8WZ42-3;Q8WZ42-10;Q8WZ42-9;Q8WZ42-5;Q8WZ42-11;Q8WZ42-4;Q8WZ42-7;Q8WZ42-2;Q8WZ42;Q8WZ42-8;Q8WZ42-13;Q8WZ42-12 A0A0A0MRA3 TTN Titin 1 CS(0.004)KT(0.996)LYR 71.342 0.03003 1460000.0 11362.0 8837.2 12127.0 8056.9 8329.3 10207.0 9155.8 7450.5 10950.0 9112.9 True False 11199.975796464381 8816.738006355954 11129.964871573733 8649.431303030504 7839.386950033863 9770.470403679128 9629.84252432654 7796.677429387481 9716.695691388146 10688.052622824016 1.0478967676999613 0.8249152878914606 1.0413463765893167 0.80926166891805 0.7334719641343351 0.9141487929068184 0.9009913090961303 0.7294759582992613 0.909117501034607 1.0 13.383711395627154 -5.77784797446949 24.994630628811933 0.8444787260055944 0.9567390859919502 0.21285461683406626 0.09800340175048772 345.3851725010054 526112.1240842937 0.026492129811427168 0.03942315155464911 1.6678309374669865e-06 5.77784797446949 0.11226035998635586 CSLHS(ph)ASPASVR ddPTM_PC-9_AZD4547_30min_R2 1 CSLHSASPASVR 12 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 CSLHS(0.647)AS(0.351)PAS(0.002)VR 94.45 0.0027798000000000002 9156800.0 11505.0 10897.0 33922.0 79327.0 46705.0 50284.0 28920.0 63251.0 29226.0 42181.0 True False 15163.35068113385 14419.242147550698 33472.172115758956 61039.385739932724 40220.8169369834 47139.733530955586 31493.823974536463 53477.011313385156 30770.82669393847 40704.25602889717 0.3725249435923588 0.35424409028171516 0.8223261000519468 1.4995823949367613 0.9881231316064206 1.1581033073664255 0.7737231200633676 1.3137940974875015 0.7559609165216861 1.0 15.312892029833751 -5.3926746818125695 3.807880749938954 1.075866385509909 0.3643023705402341 0.6266504061018724 0.214622008332229 0.13575573302238103 3.418313165896718 0.05496571346787535 0.12441104278897594 4.048790620311832e-06 5.3926746818125695 -0.7115640149696749 CSLHSAS(ph)PASVR ddPTM_PC-9_AZD4547_30min_R2 1 CSLHSASPASVR 12 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 CSLHS(0.04)AS(0.837)PAS(0.123)VR 89.46600000000001 0.0042369999999999994 7691700.0 8600.9 11803.0 44995.0 78994.0 55792.0 45312.0 25994.0 64396.0 32860.0 46234.0 True False 11335.807290166373 15618.08892975505 44398.33690078926 60783.15374513397 48046.24384002092 42478.6334769441 28307.41564294954 54445.07787286763 34596.91251498043 44615.361732534344 0.2540785695770812 0.3500607934859811 0.9951356478280703 1.3623817309724908 1.0768991211604302 0.9521077903974025 0.6344768829321684 1.220321336835991 0.7754484368497616 1.0 15.445252916589757 -5.246590462215461 5.080195739157749 1.0123965908871038 0.2869364957632228 0.6773461584775835 0.19352566428286916 0.1007064104493655 8.12833678152324 0.052018821233005864 0.13316094568388068 5.667735020357252e-06 5.246590462215461 -0.725460095123881 CSLHSAS(ph)PASVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 CSLHSASPASVR 12 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 CSLHS(0.167)AS(0.797)PAS(0.035)VR;CS(0.003)LHS(0.048)AS(0.761)PAS(0.189)VR 96.23 0.011265 5458900.0 21459.9 25338.2 52025.0 49001.0 76409.0 59062.0 47070.0 39707.0 51016.0 35988.0 True False 25092.63721765476 27853.609041669944 53265.47330591124 46255.63283338543 61437.204956596004 55964.68474729128 42611.18884271101 38664.733323044136 51762.01248721018 42512.33951914874 0.5902436210632994 0.6551888076901509 1.2529414731908364 1.088051924607692 1.4451617024963535 1.316433896141689 1.0023251913369233 0.9094943670561453 1.2175761925286452 1.0 15.375594034428694 -5.25164599924189 21.26368299704044 1.1591936168924437 0.6227152423803031 0.6546116298526724 0.15432743068743032 56.38566122136613 122419.55922515999 0.04249816856699761 0.10849452155046574 5.602140553647297e-06 5.25164599924189 -0.5364783745121406 CSLHSAS(ph)PASVR ddPTM_PC-9_Lapatinib_30min_R1 1 CSLHSASPASVR 12 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 CSLHS(0.173)AS(0.825)PAS(0.001)VR 70.438 0.029773 2662800.0 38293.0 23078.0 31743.0 27050.0 23748.0 23350.0 14241.0 13465.0 34734.0 17450.0 True False 37746.93479792383 23024.564308908088 29133.213071523467 29039.347236154732 22351.18933036438 22351.374931508533 14978.329298251832 14090.63305639922 30821.89115476491 20466.209249336556 1.844353995312906 1.1250038553013653 1.4234787066133345 1.4188923255094779 1.0921020623830928 1.0921111310455838 0.7318565502665022 0.6884828003434974 1.505989251808517 1.0 14.32095629072237 -6.397247557636647 1.8515591693096394 0.9617360006317952 1.4415881453395747 0.3915762203422978 0.2651809117485406 0.36594821052574844 2.4877363978636438 0.09537782421902234 0.11358752561207633 4.006382796827855e-07 6.397247557636647 0.4798521447077795 CSLPAEEDS(ph)VLEK ddPTM_PC-9_AZD4547_30min_R2 1 CSLPAEEDSVLEK 13 0 E7EVA0;P27816;P27816-6 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 CS(0.327)LPAEEDS(0.673)VLEK 122.46 0.0010826 0.0 11195.0 8142.6 7816.8 15980.0 13154.0 11111.0 9478.3 11303.0 12398.0 10494.0 True False 14754.777129534425 10774.536212778408 7713.14412459361 12296.057888538879 11327.794154567602 10416.227413540033 10321.850338099895 9556.381067100801 13053.332968981354 10126.608254125009 1.45703050412009 1.0639827217952733 0.7616710285451904 1.2142326018714271 1.1186168034053552 1.0285998186309864 1.0192801063372188 0.9436902097213122 1.289013324245476 1.0 13.305863426904574 -4.764550688183114 6.276277246206038 1.0429517272435058 1.4694907487087236 0.4448982915607199 0.1368389020221024 0.11120624187568227 18.927607873431434 0.03342404498782278 0.2037450831811115 1.719686618270577e-05 4.764550688183114 0.4265390214652178 CSPT(ph)VAFVEFPSSPQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 CSPTVAFVEFPSSPQLK 17 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 CS(0.02)PT(0.979)VAFVEFPSSPQLK;CS(0.03)PT(0.469)VAFVEFPS(0.395)S(0.105)PQLK 106.3 0.0016269000000000001 45404000.0 30767.0 31604.0 23425.0 40828.0 45870.0 39262.0 41622.0 37950.0 38837.0 34114.0 True False 35975.24542405062 34741.43625644038 23983.540839807214 38540.53952616194 36882.10278055015 37203.031603199175 37679.26284281532 36953.85271134875 39404.91765261451 40298.59815372459 0.8927170440723039 0.8621003669634947 0.5951457851788956 0.9563741989024955 0.9152204907937059 0.9231842621741594 0.935001825599058 0.9170009480325633 0.9778235337690653 1.0 15.298442032897086 CSPTVAFVEFPS(ph)SPQLK ddPTM_PC-9_Lapatinib_30min_R1 1 CSPTVAFVEFPSSPQLK 17 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 CSPTVAFVEFPS(0.5)S(0.5)PQLK 201.3 9.0003e-13 6173200.0 13625.0 21886.0 16325.0 17463.0 23160.0 25177.0 25399.0 28064.0 20501.0 19608.0 True False 13430.705001481016 21835.324311671833 14982.82151632235 18747.28727486027 21797.774334311922 24100.238400453534 26714.035941738533 29367.95589266895 18191.9614948994 22997.216673982304 0.5840143697335218 0.9494768267489967 0.6515058638932176 0.8151980972579976 0.9478440214451099 1.0479632706039215 1.161620396087376 1.27702218529315 0.7910505759369008 1.0 14.489171643604832 -6.411581267635732 1.9496806589964952 1.0810809692544936 0.7481521958262812 0.49268984578847097 0.14645239566946563 0.27570751896074003 2.07604881474122 0.051311594305715566 0.06014990935526021 3.8763120598325677e-07 6.411581267635732 -0.33292877342821237 CSPTVAFVEFPSS(ph)PQLK ddPTM_PC-9_AZD4547_30min_R2 2 CSPTVAFVEFPSSPQLK 17 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 CSPTVAFVEFPS(0.212)S(0.788)PQLK;CSPTVAFVEFPS(0.041)S(0.959)PQLK 307.07 5.789699999999999e-129 36693000.0 113639.0 108846.0 102754.0 90025.0 103020.0 116214.0 120656.0 112557.0 100594.0 111303.0 True False 149773.83816196158 144028.340900459 101391.41482172921 69271.12712238512 88717.45125464168 108947.12020854512 131394.15025835676 95163.90195254913 105911.19347327868 107406.31584799635 1.394460251051946 1.340967146701977 0.9439986282112166 0.6449446345447605 0.825998457857883 1.014345565699594 1.2233372797583757 0.886017746733135 0.9860797536633358 1.0 16.71271930551316 -5.249828553532746 5.414481794553954 0.9336664072694812 1.3750391819413748 0.5993763642023571 0.13979962216976874 0.12050992256907453 12.513403989207955 0.04041504422278377 0.10169112996447446 5.625633645445021e-06 5.249828553532746 0.4413727746718935 CSPTVAFVEFPSS(ph)PQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 CSPTVAFVEFPSSPQLK 17 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 CSPTVAFVEFPS(0.215)S(0.785)PQLK;CSPTVAFVEFPS(0.225)S(0.775)PQLK 230.67 1.6661e-29 18476900.0 55863.0 55597.0 46469.0 64343.0 81525.0 54256.0 80690.0 52313.0 54234.0 56199.0 True False 65319.502555456864 61116.30273222741 47576.99719466386 60738.07031282051 65550.76148210942 51410.71984777069 73046.45905498933 50939.83918020518 55027.06964935233 66387.43382896083 0.9839136533541067 0.9206004692045509 0.7166566690503541 0.9149031196070145 0.9873971277605489 0.7744043847247384 1.1003055072618815 0.7673114660742196 0.8288777932149464 1.0 16.018622565875795 -4.995737776785155 20.340050084158396 0.8817049425119443 0.9680865249203343 0.06228931117967795 0.11354924039644013 36.27408664945108 172960.62775175468 0.02728246798412955 0.10244002920276357 1.0098624481596287e-05 4.995737776785155 0.08638158240839 CSPTVAFVEFPSS(ph)PQLK ddPTM_PC-9_Lapatinib_30min_R1 1 CSPTVAFVEFPSSPQLK 17 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 CSPTVAFVEFPS(0.171)S(0.829)PQLK 127.07 3.5099000000000004e-05 6398100.0 37216.0 61469.0 53723.0 62829.0 78164.0 70476.0 87462.0 83502.0 81037.0 77517.0 True False 36685.29301542145 61326.672307144094 49306.10231677708 67449.65425139989 73566.54719633667 67461.9057675801 91990.3544051474 87381.80775903817 71909.75970255905 90915.71016509006 0.40350884295801187 0.6745442805845495 0.5423276376243906 0.7418921782486312 0.8091731017967108 0.7420269351147214 1.0118202259885112 0.961129903735726 0.7909497662393123 1.0 16.472241992108643 -4.755565798039098 0.3330239309832972 0.9825709427914311 0.035718442312240035 0.7699699157315094 0.08929910937788783 3.341759823147598 0.29526578049200175 0.09049891439629382 1.2947594719703444 1.7556348855601727e-05 4.755565798039098 -0.946852500479191 down CSQAVYAAEK ddPTM_PC-9_Lapatinib_30min_R1 2 CSQAVYAAEK 10 0 E9PP21;P21291;E9PND2;E9PS42 E9PP21 CSRP1 Cysteine and glycine-rich protein 1 0 ; 145.55 0.00052744 8751200.0 28416.0 26907.0 31016.0 26997.0 29493.0 25959.8 28593.0 23159.0 23723.2 28905.0 False True 28010.7826291438 26844.698494661163 28465.984205222318 28982.449439351934 27758.27972546898 24849.559869249486 30073.40563337651 24235.051686086124 21051.243399629144 33901.19073650849 0.8262477517929404 0.7918511978917564 0.8396750552648597 0.8549094828147283 0.8187995501755589 0.7329996182844627 0.8870899511205131 0.7148731699263644 0.6209588200971028 1.0 15.049048326642232 -6.551558928390948 22.676466179281604 0.7789736427715891 0.8277053934995018 0.024982572257289504 0.09690404315457075 253.54735431638335 200467.411335375 0.0311465046333478 0.031147577011874688 2.808284297461429e-07 6.551558928390948 0.04873175072791269 CSS(ph)VTGVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CSSVTGVQR 9 0 O60343-2;A0A3B3IRT3;O60343-3;O60343 O60343-2 TBC1D4 TBC1 domain family member 4 1 CS(0.146)S(0.709)VT(0.146)GVQR 77.288 0.023277000000000003 3550800.0 16667.0 18128.0 26542.0 26051.0 33383.0 20184.0 30088.0 37040.0 25570.0 20215.0 True False 19488.393911744784 19927.6280362217 27174.86194109555 24591.446928481542 26841.84079187062 19125.515508098713 27237.846821743966 36067.739247124046 25943.91287631261 23879.819478148056 0.8161030668417835 0.834496594685612 1.1379843958185163 1.02980036976346 1.1240386811312812 0.8009070389162736 1.1406219735734926 1.5103857581557059 1.0864367253719553 1.0 14.543504309997855 -7.514262550926109 24.963353511158335 1.2441475126140935 0.9707432982347157 0.29727705813407324 0.16782175691072437 450.35733953522816 1304813.4660609667 0.07423449759157756 0.04561319637267107 3.060112895832095e-08 7.514262550926109 -0.2734042143793778 CSSCEPFPDGATNNLS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 CSSCEPFPDGATNNLSR 17 0 O95999 O95999 BCL10 B-cell lymphoma/leukemia 10 1 CSSCEPFPDGAT(0.01)NNLS(0.99)R 133.95 2.5719000000000002e-05 4224500.0 8609.6 8158.4 8042.3 8062.2 10343.0 11570.0 12036.0 14789.0 11955.0 7676.0 True False 11347.27370919514 10795.443253792568 7935.653847254533 6203.584349748324 8907.052983175661 10846.526070979955 13107.180683178456 12503.699867411628 12586.916893383774 7407.265576392565 1.5319112825331438 1.4574127446163594 1.071333782407637 0.8374999229836647 1.2024751767457909 1.4643090569816393 1.769503273239168 1.6880318031611732 1.6992663167767459 1.0 12.854725348457146 -6.8846652665733465 3.9454343785560284 1.5987559847970805 1.2041278115870166 0.2300227708593664 0.27040005401887235 0.2905677435129568 8.386038601493158 0.10242941925318201 0.0898665807661733 1.3041715842900052e-07 6.8846652665733465 -0.3946281732100638 CSSCEPFPDGATNNLS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 2 CSSCEPFPDGATNNLSR 17 0 O95999 O95999 BCL10 B-cell lymphoma/leukemia 10 1 CSSCEPFPDGAT(0.041)NNLS(0.959)R;CSSCEPFPDGAT(0.002)NNLS(0.998)R 107.63 0.00057773 9145500.0 24815.3 38199.0 31281.0 30933.0 40297.0 42082.0 38165.0 40286.0 39957.0 38298.0 True False 24461.429271431327 38110.55256243958 28709.196928151876 33207.916009463035 37926.80968695025 40282.250957933305 40140.996957220814 42157.83463127357 35456.62189413662 44917.75827112272 0.5445825930088187 0.8484517934400247 0.6391502611253153 0.7393048381671385 0.8443611423799192 0.8968001188926308 0.893655393818421 0.9385560690008101 0.7893675744038946 1.0 15.454998307914934 -6.301592519537381 2.135646296320097 0.8993572541665714 0.69215775055831 0.5805743258396754 0.08561491887067367 0.23779518025314406 2.129445476150755 0.027630987512116168 0.034643995423542816 4.993527897003232e-07 6.301592519537381 -0.20719950360826145 CSSDANMLGEMMFGSVAMS(ph)Y(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 CSSDANMLGEMMFGSVAMSYK 21 0 J3KNG8;Q8TF40;Q8TF40-2;Q8TF40-3 J3KNG8 FNIP1 Folliculin-interacting protein 1 2 CS(0.002)S(0.003)DANMLGEMMFGS(0.039)VAMS(0.979)Y(0.978)K 46.361999999999995 0.04068 0.0 5418.1 3206.1 3885.4 6534.7 5026.1 3675.8 4128.1 5470.9 4693.8 4462.5 True False 7140.943096519023 4242.409126297355 3833.8770573247393 5028.225875108576 4328.312771801143 3445.951644918593 4495.492902810647 4625.498113775257 4941.904685417378 4306.269233279287 1.6582667524206542 0.9851704332631099 0.8903012908937852 1.1676524626583806 1.0051189410897725 0.8002174175009608 1.0439414396269098 1.074131194127143 1.1476069928990587 1.0 12.07222280606559 -4.76010132400661 24.999440139278448 1.0101181911014854 1.658267536752721 0.7762144079518105 0.10398370632831717 16.06172049188947 299975.34938720585 0.02684858360261098 0.1628503877223789 1.7373954346881545e-05 4.76010132400661 0.6481493456512357 CSVCPDYDLCS(ph)VCEGK ddPTM_PC-9_AZD4547_30min_R2 2 CSVCPDYDLCSVCEGK 16 0 Q13501;Q13501-2;E7EMC7;E9PFW8;E3W990;C9JRJ8 Q13501 SQSTM1 Sequestosome-1 1 CSVCPDYDLCS(1)VCEGK;CSVCPDYDLCS(1)VCEGK 103.67 0.0013325 28117000.0 86463.0 70544.0 90905.0 135450.0 100093.0 91097.0 100303.0 109229.0 84214.0 105545.0 True False 113956.43545787732 93345.9684368923 89699.54030372809 104224.09518163916 86196.81468094395 85400.69018911498 109229.77268734219 92350.16788271745 88665.38011371164 101849.90167539754 1.1188664258220309 0.9165052386048653 0.8807032586993214 1.0233107098503476 0.8463122031836513 0.8384955585062094 1.072458302762675 0.9067281005046388 0.8705494915085352 1.0 16.636085061981802 -4.759713301425986 24.89429593987532 0.9260373874193951 1.1188666786752899 0.3681510290301502 0.074825886331377 46.082552740463576 664415.3887964529 0.018360459619445355 0.1141817349381588 1.738948412998254e-05 4.759713301425986 0.19282929125589476 CSVCPDYDLCS(ph)VCEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 CSVCPDYDLCSVCEGK 16 0 Q13501;Q13501-2;E7EMC7;E9PFW8;E3W990;C9JRJ8 Q13501 SQSTM1 Sequestosome-1 1 CSVCPDYDLCS(1)VCEGK;CSVCPDYDLCS(1)VCEGK 169.64 3.2283999999999997e-21 4578800.0 55773.0 55683.0 47893.0 60545.0 68025.0 60541.0 61687.0 74411.0 52295.0 43345.0 True False 65214.267333037904 61210.84024387321 49034.95075521396 57152.85993953842 54695.989571548416 57366.12338366054 55843.560784795285 72457.79009497169 53059.71544257987 51203.10538116881 1.273638910131846 1.1954517170043555 0.9576557982213274 1.1161990960133792 1.068216256892579 1.120364145037936 1.0906283978106748 1.4151053838547027 1.0362597160385096 1.0 15.643943689426166 CSVCPDYDLCS(ph)VCEGK ddPTM_PC-9_Lapatinib_30min_R1 2 CSVCPDYDLCSVCEGK 16 0 Q13501;Q13501-2;E7EMC7;E9PFW8;E3W990;C9JRJ8 Q13501 SQSTM1 Sequestosome-1 1 CSVCPDYDLCS(1)VCEGK;CSVCPDYDLCS(1)VCEGK 189.59 3.0295e-08 18868200.0 73430.0 143879.0 170873.0 164903.0 161480.0 162393.0 137887.0 159039.0 171961.0 136925.0 True False 72382.87473458727 143545.85701539958 156824.48152885464 177030.51672028235 151982.0638818949 155447.82994657254 145026.11417372728 166428.53254041413 152592.9413503923 160592.30380890585 0.4507244308588914 0.8938526542729569 0.9765379648296554 1.102359904687194 0.9463844796867938 0.9679656263698982 0.9030701393156343 1.0363418955521866 0.9501883822027221 1.0 17.293043229541254 -4.73925129391234 2.825895394921688 0.9848971996086289 0.31901936009816634 0.9056516960361435 0.05152722639885461 0.1420211046441108 1.4196293046969617 0.013551047474999797 0.23224891306463785 1.8228406548126187e-05 4.73925129391234 -0.6658778395104625 down CSVS(ph)AVNLPK ddPTM_PC-9_AZD4547_30min_R2 2 CSVSAVNLPK 10 0 Q3KQU3-4;Q3KQU3;C9JIR3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 CSVS(1)AVNLPK;CS(0.007)VS(0.993)AVNLPK 130.44 0.00021314 54750000.0 165409.0 181478.0 233514.0 346440.0 319990.0 325470.0 307770.0 280290.0 277010.0 360430.0 True False 218005.62127906733 240137.2145042863 230417.45178466305 266573.6104446443 275564.91192945815 305118.30944873363 335160.9337705079 236977.62092344335 291652.18307287694 347811.4554063537 0.6267925276479691 0.690423534853762 0.6624780414879167 0.766431370505615 0.7922824497183718 0.8772520418922345 0.9636282202923249 0.6813393211749699 0.8385352999145328 1.0 18.40794592400419 -6.045719676387988 1.4418878158530926 0.8560321059841312 0.6538767807305189 0.5472890163402206 0.0822397202498323 0.34917017370163 1.466322471765033 0.029661770420448336 0.05026782945452034 9.000783667269589e-07 6.045719676387988 -0.20215532525361224 CSVS(ph)AVNLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 CSVSAVNLPK 10 0 Q3KQU3-4;Q3KQU3;C9JIR3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 CS(0.055)VS(0.945)AVNLPK;CS(0.007)VS(0.993)AVNLPK;CS(0.001)VS(0.999)AVNLPK;CSVS(1)AVNLPK 142.19 0.00012641 66896800.0 203109.0 237146.0 267263.0 354852.0 391629.0 324723.0 340005.0 339968.0 311411.0 238778.0 True False 237491.34211439255 260688.28763668513 273635.56352057203 334970.7928857069 314892.1087823002 307693.9542378293 307797.2649769697 331044.2002258712 315964.7967432692 282066.561234392 0.8419691475482687 0.9242084084545494 0.9701099000288306 1.1875593881805524 1.1163751825252013 1.0908558352017539 1.0912220988903252 1.1736385864993748 1.1201781429196367 1.0 18.105676120152125 -5.548814507898013 3.437097098837368 1.1169005040699036 0.8895064158911395 0.7572671607443946 0.05280294171945299 0.10432123664474367 2.5786357155614974 0.014285303745496504 0.028694902712560064 2.826086770912073e-06 5.548814507898013 -0.22739408817876405 CT(ph)CPDQFPMIK ddPTM_PC-9_AZD4547_30min_R2 2 CTCPDQFPMIK 11 0 A0A5E8;Q99501;Q99501-2;Q99501-4;Q99501-3 A0A5E8 GAS2L1 GAS2-like protein 1 1 CT(1)CPDQFPMIK;CT(1)CPDQFPMIK 110.38 0.004076099999999999 6217600.0 4437.3 6496.0 35086.0 28797.0 23779.0 10135.0 6412.1 44776.0 9862.3 10507.3 True False 5848.269098426362 8595.704963796397 34620.736715214836 22158.296559214912 20477.696305417594 9501.256847829025 6982.764478116364 37856.89805011991 10383.601043715502 10139.442625173215 0.5767840811985909 0.847749258174786 3.4144615236799964 2.1853564715877445 2.0196076907203535 0.9370590868811897 0.6886734050627439 3.7336271281946516 1.0240800631324758 1.0 13.307690727748712 CT(ph)CPDQFPMIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CTCPDQFPMIK 11 0 A0A5E8;Q99501;Q99501-2;Q99501-4;Q99501-3 A0A5E8 GAS2L1 GAS2-like protein 1 1 CT(1)CPDQFPMIK 89.46 0.019441 2731800.0 1195.4 1174.6 30079.0 3172.7 7500.9 1335.3 2837.4 1900.6 3519.8 1588.8 True False 1397.7576097737876 1291.2065253390338 30796.19743524275 2994.943905032181 6031.152490661189 1265.2745173386954 2568.6209310029376 1850.711263852159 3571.2704161926117 1876.8368630661205 0.7447411318905585 0.6879695037690363 16.40856381354963 1.5957401327569034 3.213466556069404 0.6741526353396865 1.3685904095077686 0.9860799839729911 1.9028134445091602 1.0 10.87408753947981 -5.924640406488128 24.999998613524056 1.5562839520456082 6.017989801444617 0.1952230843527798 4.104813376799798 63.23726833421295 20976.127359588892 1.176678366168356 1.7452961642519311 1.1894867084509706e-06 5.924640406488128 4.461705849399009 CT(ph)CPDQFPMIK ddPTM_PC-9_Lapatinib_30min_R1 1 CTCPDQFPMIK 11 0 A0A5E8;Q99501;Q99501-2;Q99501-4;Q99501-3 A0A5E8 GAS2L1 GAS2-like protein 1 1 CT(1)CPDQFPMIK 91.62 0.016971 1749000.0 3067.6 3042.8 11309.0 3151.5 4747.8 7384.0 5457.1 5009.0 8748.7 4304.2 True False 3023.8554614710565 3035.7545835490746 10379.217674002419 3383.2718230958108 4468.543738533943 7068.20353294471 5739.641936204629 5241.73642625352 7763.329278104786 5048.175235014007 0.5989997020106744 0.6013568155267597 2.05603355486007 0.6701969851659524 0.8851799968313787 1.4001501936620269 1.1369735932292184 1.0383428035336368 1.5378486119615151 1.0 12.301546275469434 -5.092893670203462 20.58081626033695 1.1987547133826644 0.5977834199841778 0.3110317446584798 0.3656831542612324 12.828553474911295 2838.3817360039548 0.08997852600764876 0.23806342964915053 8.074326925456646e-06 5.092893670203462 -0.6009712933984865 CT(ph)EKSTYMNSY(ph)SK ddPTM_PC-9_AZD4547_30min_R2 1 CTEKSTYMNSYSK 13 1 E9PLN1;E9PMC1;Q9H5F2 E9PLN1 C11orf1 UPF0686 protein C11orf1 2 CT(1)EKS(0.181)T(0.139)Y(0.072)MNS(0.211)Y(0.316)S(0.082)K 71.085 0.026174 0.0 1572.7 0.0 1299.2 2235.4 2567.1 1375.0 1725.0 2351.0 0.0 1631.6 True False 2072.7858858078416 0.0 1281.971759117801 1720.0630665857218 2210.7024763714817 1289.0210326359052 1878.521658232205 1987.7069706055022 0.0 1574.4781806203882 1.3164907023297752 0.0 0.8142200856747779 1.092465483331099 1.404085813053569 0.8186972982553464 1.1931074570319007 1.2624544405069433 0.0 1.0 10.620658049166925 -4.476909162936122 23.63012750150587 0.8722532930696135 6.735040411824372 0.08350626668297645 0.46160053092093495 1397.722837979545 759240.4885985088 0.11181177605658263 23375.33249850328 3.334961595486605e-05 4.476909162936122 5.862787118754758 CTELNQAWS(ph)SLGK ddPTM_PC-9_AZD4547_30min_R2 1 CTELNQAWSSLGK 13 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 1 CTELNQAWS(0.638)S(0.362)LGK 194.77 1.2392e-06 2766500.0 17742.0 17717.0 23476.0 26531.0 20222.0 24288.0 20264.0 25272.0 20389.0 22108.0 True False 23383.58694347475 23443.673775181764 23164.6929010541 20414.687849863894 17414.52435712832 22769.267520480644 22067.456743430386 21366.793092786993 21466.720915031514 21334.005649151484 1.0960710955096604 1.098887576985065 1.085810760623635 0.9569083361837324 0.8162801043329126 1.0672757800355341 1.0343794365831187 1.0015368629864787 1.006220832039824 1.0 14.380867249475926 -5.730878473348336 9.21927249243506 0.981981050316963 1.094442823037822 0.3929597785954936 0.0628451611721267 0.3342715737567279 93.36285661748559 0.01847315327688634 0.031648795231889 1.858324388813427e-06 5.730878473348336 0.112461772720859 CTELNQAWSS(ph)LGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CTELNQAWSSLGK 13 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 1 CTELNQAWS(0.238)S(0.762)LGK 89.624 0.0060143 3356500.0 17142.0 21325.0 15624.0 24647.0 25760.0 17630.0 21760.0 19900.0 14957.0 17092.0 True False 20043.80203006716 23442.005067984763 15996.535414349952 23266.108496652138 20712.512919707264 16705.451764158755 19698.735271242665 19377.646085792872 15175.717829136014 20190.644299802454 0.9927272122892715 1.1610330368810529 0.7922746385317908 1.152321250931045 1.0258470513449596 0.8273857691763805 0.9756367839849172 0.9597339142853636 0.7516212758641136 1.0 14.30139932851991 -6.733687622775288 23.89526821935122 0.9049065220664614 1.0265689317987245 0.213961064515946 0.11682947534428921 210.95176190303377 181635.972887931 0.037176297533373995 0.03716586380414492 1.8463429702852942e-07 6.733687622775288 0.12166240973226317 CTELNQAWSS(ph)LGK ddPTM_PC-9_Lapatinib_30min_R1 2 CTELNQAWSSLGK 13 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 1 CTELNQAWS(0.018)S(0.982)LGK;CTELNQAWS(0.106)S(0.894)LGK 178.68 0.00012085 5845700.0 27457.0 37846.0 43973.0 41192.0 42519.0 43398.0 37338.0 38104.0 37071.0 34567.0 True False 27065.458145002856 37758.36991225131 40357.70968068869 44221.39709248381 40018.116015570304 41541.96870567912 39271.1789437629 39874.45094549098 32895.67360506393 40541.85989236776 0.6675929080919667 0.9313428148706998 0.9954577759341097 1.0907589639420747 0.9870814047952435 1.024668547914834 0.9686575566099257 0.9835377817236644 0.8114002093736389 1.0 15.307124654736754 -4.757142616072088 3.083933053737246 0.9864937910978377 0.6071416100835655 0.6694029802344734 0.06604929529705858 0.24094005877223296 3.2264571635224266 0.017232781981917987 0.23308988748412912 1.749272158435985e-05 4.757142616072088 -0.37935218101427226 CTGDFSPS(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 4 CTGDFSPSPEK 11 0 A0A2R8YH03;Q5VWN6;Q5VWN6-2 A0A2R8YH03 FAM208B Protein FAM208B 1 CTGDFS(0.003)PS(0.997)PEK;CTGDFS(0.042)PS(0.958)PEK;CTGDFS(0.042)PS(0.958)PEK;CTGDFS(0.08)PS(0.92)PEK 131.79 0.00014078 42548900.0 225201.0 196513.0 217515.0 245710.0 239809.0 230420.0 244801.0 233389.0 206875.0 242827.0 True False 296810.2335282077 260031.98422883655 214630.60897822396 189065.35568165782 206515.65975465227 216011.8009745206 266587.8147576242 197324.09279568106 217809.99015631707 234325.70064078635 1.2666567632852535 1.1097032187154625 0.9159499294840291 0.8068485666089561 0.8813188616951327 0.9218442551705399 1.1376806471872865 0.8420932584692127 0.9295181431686517 1.0 17.838155670863998 -5.020177030580601 2.6694206470006776 0.9249050008981179 1.2676074417519445 0.613377525710751 0.08638521426739929 0.21273002945980485 2.7257466971267594 0.024053957779939406 0.127796821295643 9.546033836568765e-06 5.020177030580601 0.3427024408538266 CTGDFSPS(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 CTGDFSPSPEK 11 0 A0A2R8YH03;Q5VWN6;Q5VWN6-2 A0A2R8YH03 FAM208B Protein FAM208B 1 CTGDFS(0.003)PS(0.997)PEK;CT(0.001)GDFS(0.034)PS(0.964)PEK;CTGDFS(0.001)PS(0.999)PEK;CTGDFS(0.077)PS(0.923)PEK 124.48 0.00050912 32464300.0 175067.0 164144.0 139342.0 209116.0 203561.0 165398.0 189820.0 211986.0 168694.0 137159.0 True False 204702.38536913827 180439.13153009576 142664.44173747793 197399.90848321933 163674.6833248653 156724.2377134619 171838.87542220968 206421.59211773265 171160.83061230675 162024.84094995327 1.2634012424821164 1.1136510332130514 0.8805096854348683 1.2183311356817985 1.0101826507913167 0.967285243389755 1.0605711717704311 1.2740120027736537 1.0563863516778604 1.0 17.305855492286902 -10.499788093744103 15.10092667485496 1.000000001673174 1.089927482223664 0.0498855209436182 0.12176761975058353 0.0 0.0 0.11847712634316256 0.028734923890147528 3.1638210137149726e-11 10.499788093744103 0.08992748055048994 CTGDFSPS(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 3 CTGDFSPSPEK 11 0 A0A2R8YH03;Q5VWN6;Q5VWN6-2 A0A2R8YH03 FAM208B Protein FAM208B 1 CTGDFS(0.026)PS(0.974)PEK;CTGDFS(0.019)PS(0.981)PEK;CT(0.004)GDFS(0.052)PS(0.944)PEK 145.29 9.6448e-05 31014200.0 158561.0 186141.0 176507.0 204508.0 187685.0 189352.0 166777.0 170081.0 176352.0 162638.0 True False 156299.89106347412 185710.00195096887 161995.2757967232 219548.20053868875 176645.7373029071 181253.85636107094 175411.89701387155 177983.5841712165 156489.38069111234 190749.7615984871 0.8193975696413861 0.9735792086695945 0.8492554561494563 1.1509749668826326 0.9260600685558505 0.9502179968255778 0.9195916972263352 0.9330736913100716 0.8203909634262605 1.0 17.54132172839887 -10.334736401178768 14.923219431119081 0.9999999994302033 0.9332464100494415 0.051245334694690836 0.09072541485868817 0.0 0.0 0.08575731607265426 0.020799204255119566 4.626617527780104e-11 10.334736401178768 -0.06675358938076181 CTGGEVGATSALAPK ddPTM_PC-9_Lapatinib_30min_R1 1 CTGGEVGATSALAPK 15 0 P30050;P30050-2 P30050 RPL12 60S ribosomal protein L12 0 151.55 8.9699e-10 0.0 11963.0 10400.0 12321.0 11868.0 10266.0 9867.9 11078.0 9017.0 9881.5 12663.0 False True 11792.405426254489 10375.91943897409 11308.014940435392 12740.812310487407 9662.174063732562 9445.872920198412 11651.5646349297 9435.96273817689 8768.541413191957 14851.782677613124 0.794006058547423 0.6986312461071936 0.761391085898433 0.857864176109465 0.6505733536147729 0.6360093683862392 0.7845229685788978 0.6353420961646722 0.5904032939028419 1.0 13.858348489416839 -10.551362292839883 4.290410305625022 1.0000184844504705 0.7132519187309639 0.5301824300728075 0.08130275606392641 13621936.49741493 4189381.290202514 2437.245643005484 0.020423269461761213 2.8095560924853483e-11 10.551362292839883 -0.28676656571950654 CTKEEHLCTQR ddPTM_PC-9_AZD4547_30min_R2 1 CTKEEHLCTQR 11 1 A0A087WWU8;P06753-5;P06753-2;P06753-7;J3KN67 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 61.48 0.02665 5893500.0 57847.0 47627.0 70759.0 114030.0 98949.0 65451.0 60295.0 76619.0 58425.0 80518.0 False True 76241.14270765323 63021.49635325293 69820.68942689075 87742.14524593792 85211.63933406632 61358.33862331106 65661.13819310772 64779.29407946523 61513.22622299852 77699.0893277718 0.9812359883142483 0.8110969755050567 0.8986037034791206 1.1292557738456848 1.0966877484831643 0.7896918632401512 0.8450695981276916 0.8337201200157609 0.7916852920052436 1.0 16.24561006917334 -6.78051605634749 24.99982596851537 0.8412056382284823 0.9771998721162096 0.2942521956910481 0.10078431112845933 338.28836482926994 443321.1506722129 0.03833970758076822 0.0338648867760867 1.6576160518166143e-07 6.78051605634749 0.13599423388772736 CTLPEHES(ph)PSQDISDACEAESTER ddPTM_PC-9_AZD4547_30min_R2 5 CTLPEHESPSQDISDACEAESTER 24 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 CTLPEHES(0.998)PS(0.002)QDISDACEAESTER;CTLPEHES(0.923)PS(0.076)QDISDACEAESTER;CTLPEHES(0.988)PS(0.012)QDISDACEAESTER;CTLPEHES(0.989)PS(0.011)QDISDACEAESTER;CT(0.006)LPEHES(0.992)PS(0.002)QDISDACEAESTER 149.18 1.4439000000000002e-09 561250000.0 92713.8 97199.7 140248.0 149383.0 158690.0 145171.0 113203.0 164471.0 118621.6 134747.0 True False 122194.85983316033 128617.60218126862 138388.21988358482 114945.05729434325 136658.6326887889 136093.43442093593 123277.84769673068 139055.7861175913 124891.69560520393 130029.54854379449 0.9397468590918363 0.9891413422692127 1.0642828605759183 0.883991820179467 1.0509813670756667 1.046634676079792 0.9480756418623586 1.0694168185222666 0.9604870354767086 1.0 16.988479979948693 CTLPEHES(ph)PSQDISDACEAESTER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 CTLPEHESPSQDISDACEAESTER 24 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 CT(0.001)LPEHES(0.959)PS(0.039)QDISDACEAESTER;CTLPEHES(0.999)PS(0.001)QDISDACEAESTER;CT(0.002)LPEHES(0.996)PS(0.002)QDISDACEAESTER;CTLPEHES(0.967)PS(0.025)QDIS(0.008)DACEAESTER 159.67 4.4034e-09 338076000.0 83955.0 85435.0 105642.0 109329.0 124664.0 98825.3 111111.0 92836.0 92312.0 80299.0 True False 98166.92331316571 93916.42217975495 108160.9059295158 103203.65057940055 100236.98410801179 93642.72729600228 100585.76170602233 90399.15336787292 93661.88836285393 94856.57305346591 1.0348984804440904 0.9900887113728952 1.1402573638049405 1.087996827813185 1.0567215416006355 0.9872033564107419 1.0603984359557999 0.9530088475462785 0.9874053568228889 1.0 16.533460127704636 -7.120899783929412 1.2342922219231247 0.9853436977799632 1.063053798693483 0.3252293677903635 0.04442518629686406 0.5753924977003739 1.7525297121922334 0.02821756321875595 0.018296560051712003 7.570075589269653e-08 7.120899783929412 0.07771010091351971 CTLPEHES(ph)PSQDISDACEAESTER ddPTM_PC-9_Lapatinib_30min_R1 5 CTLPEHESPSQDISDACEAESTER 24 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 CTLPEHES(0.942)PS(0.058)QDISDACEAESTER;CT(0.064)LPEHES(0.931)PS(0.005)QDISDACEAESTER;CTLPEHES(0.998)PS(0.002)QDISDACEAESTER;CTLPEHES(0.995)PS(0.005)QDISDACEAESTER;CT(0.003)LPEHES(0.473)PS(0.473)QDIS(0.044)DACEAES(0.005)T(0.002)ER 146.19 6.6911e-09 480590800.0 129525.4 234862.2 303423.0 249761.9 280420.8 275190.9 255104.0 285447.8 284006.4 237795.7 True False 127678.34404395067 234318.3910057905 278476.73218665086 268130.2233072739 263926.99987250497 263421.6267083202 268312.03688654175 298710.7468664269 252018.60851202323 278898.3699021471 0.45779523232332714 0.8401569040650984 0.9984882030122866 0.9613904283533414 0.9463196216066271 0.9445075881968871 0.9620423273921622 1.071037980506057 0.9036216618994412 1.0 18.08937997660167 -4.761142776889716 2.4401959073443993 0.9729434251197259 0.3231343001598929 0.9301371107894959 0.04254657656847389 0.13337176403481976 0.9444588621733079 0.010892056039158065 0.18885110817671433 1.7332340930796563e-05 4.761142776889716 -0.649809124959833 down CTNINSDS(ph)PVGKK ddPTM_PC-9_Lapatinib_30min_R1 1 CTNINSDSPVGKK 13 1 A0A087WV86;Q6PGQ7-2;Q6PGQ7;H3BLY2 A0A087WV86 BORA Protein aurora borealis 1 CT(0.003)NINS(0.017)DS(0.98)PVGKK 53.995 0.038256 3430800.0 19019.0 15516.0 12321.0 21941.0 15770.0 14415.0 10349.0 13667.0 16066.0 12943.0 True False 18747.785572342567 15480.073655300204 11308.014940435392 23554.614333030353 14842.439605012903 13798.504053006236 10884.82058195409 14302.018713836474 14256.4778975198 15180.180304536565 1.2350173183871755 1.0197555855561227 0.7449196724663419 1.5516689433518194 0.9777512063264012 0.9089815651848735 0.7170415873585628 0.9421507799589407 0.9391507618166618 1.0 13.889901306199793 -6.513672444501281 24.82065643332477 0.8926610188626835 1.1217612341758592 0.23711360097689693 0.19932461676408994 631.8611061067804 1703535.3084659164 0.06465789174123258 0.06815522783063105 3.0642737123750064e-07 6.513672444501281 0.2291002153131757 CTVFHGAQVEDAFR ddPTM_PC-9_AZD4547_30min_R2 1 CTVFHGAQVEDAFR 14 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 72.681 0.018654 2708000.0 6484.1 6310.2 6873.9 12224.0 8227.1 9891.9 5626.9 8689.8 7261.0 7163.7 False True 8545.9089223416 8349.84874731343 6782.747594673525 9405.945658917348 7084.909175083097 9273.357929258995 6127.683199250315 7346.991081738695 7644.8016363747065 6912.901043460581 1.2362261326488682 1.2078646424733888 0.9811723836391123 1.3606365257918918 1.024882192084209 1.3414567734961782 0.8864126884973913 1.0627941924163304 1.105874594227916 1.0 12.755075558617538 -7.2669052449893465 24.99977493960269 1.0190032272799752 1.1832396218880683 0.33066183509890623 0.12378619468426477 581.6919343745016 2660527.2089434597 0.048174777764534354 0.03352356943731112 5.408723183931254e-08 7.2669052449893465 0.16423639460809314 CTVFHGAQVEDAFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CTVFHGAQVEDAFR 14 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 84.759 0.0060097 1952700.0 11803.0 11802.0 12267.0 13512.0 16970.0 10650.0 16086.0 11529.0 12396.0 11669.0 False True 13801.014780123814 12973.62456329924 12559.491802856572 12754.966446495053 13644.850320164302 10091.495251746499 14562.217627445278 11226.37596598523 12577.268049072007 13784.497328246829 1.0011982629096774 0.9411750210661676 0.9111316505622582 0.9253124102217287 0.9898692709094029 0.7320901888143047 1.0564199245484829 0.8144204100196266 0.9124212330397424 1.0 13.750759037882819 -1.522885640951195 0.8579299582324947 0.9095176123610356 35.457477230426015 0.07149803558872725 0.08770708565133664 1746.9050754500333 4.692470912401175 0.028070992542574138 117855.65144161346 0.0299995236677139 1.522885640951195 34.54795961806498 CTYLVLDEADR ddPTM_PC-9_Lapatinib_30min_R1 1 CTYLVLDEADR 11 0 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 119.53 0.0044051 2590000.0 13587.0 9320.2 11963.0 8652.1 11135.0 11427.0 9520.1 7726.0 10235.0 8749.0 False True 13393.246888449356 9298.619649531387 10979.44831851543 9288.4042965595 10480.061192252302 10938.293847638024 10013.00419579295 8084.978165149673 9082.226520671926 10261.252992690292 1.3052252875930621 0.906187544167886 1.069990996843831 0.9051920173078463 1.0213237310996894 1.065980329637134 0.975807165355519 0.7879133445895048 0.8850991713333394 1.0 13.324919287489402 -7.55410804976725 7.63559224325666 0.8774963871746103 1.0320210452947074 0.259791065097868 0.11505273506686915 0.270640980761869 52.72888001830702 0.05154402577497059 0.02988962376877016 2.7918491601096018e-08 7.55410804976725 0.15452465812009708 CVACQNPDKPS(ph)PSTSVPAPASFK ddPTM_PC-9_AZD4547_30min_R2 1 CVACQNPDKPSPSTSVPAPASFK 23 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 CVACQNPDKPS(0.71)PS(0.179)T(0.048)S(0.063)VPAPASFK 90.09700000000001 9.889e-06 19019000.0 76371.0 68083.0 82479.0 97343.0 102360.0 99836.0 87632.0 96362.0 83591.0 84630.0 True False 100655.38938451737 90089.49831437033 81385.27456917876 74902.07528435792 88149.0808622122 93593.23913762798 95431.07823432132 81471.46707847173 88009.44960559123 81667.12945936705 1.232507987618174 1.1031304627793215 0.9965487351881454 0.9171630713630625 1.0793703837242157 1.1460331685123657 1.1685371931898554 0.9976041476884201 1.0776606229239363 1.0 16.317467898455853 -6.8188000356240535 0.008932119937660807 1.88367802626184e-07 2.1418201943415065 0.08770854031211917 0.08649394745189624 11221.21061673677 40.956461585895084 4795.264329869249 5021.90525759218 1.5177490313642155e-07 6.8188000356240535 2.141820005973704 CVACQNPDKPS(ph)PSTSVPAPASFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 CVACQNPDKPSPSTSVPAPASFK 23 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 CVACQNPDKPS(0.532)PS(0.179)T(0.145)S(0.145)VPAPASFK;CVACQNPDKPS(0.365)PS(0.08)T(0.277)S(0.277)VPAPAS(0.001)FK 86.625 1.4293e-05 27673000.0 120226.0 133602.0 121937.0 145321.0 150244.0 139270.0 158540.0 124423.0 129379.0 126335.0 True False 140577.88722826104 146865.12361514228 124844.4405286477 137179.135507039 120804.76673557851 131966.43602917687 143521.943469798 121157.02808706586 131270.92311397943 149238.53543269058 0.9419677486158683 0.9840965216479308 0.8365429221526696 0.9191937934080665 0.8094743518175556 0.8842651507304308 0.9616949339102105 0.8118347431901058 0.8796047397100403 1.0 17.187260581741384 -5.250665831581021 24.95841448221914 0.8819391023156248 0.9630321414364735 0.2012692447028802 0.0590018086467364 977.1074175618932 2263592.7743019783 0.01423542209262084 0.03681723527930351 5.614798412104452e-06 5.250665831581021 0.08109303912084875 CVACQNPDKPSPS(ph)TSVPAPASFK ddPTM_PC-9_AZD4547_30min_R2 1 CVACQNPDKPSPSTSVPAPASFK 23 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 CVACQNPDKPS(0.307)PS(0.477)T(0.161)S(0.055)VPAPASFK 84.993 1.6364e-05 20989000.0 121490.0 98908.0 126410.0 168190.0 137180.0 147910.0 147960.0 165880.0 129180.0 153400.0 True False 160121.2928510168 130878.07674864138 124733.72080517323 129416.39400959657 118134.92489916249 138661.1643179469 161128.15336349953 140247.05754319066 136008.1910738032 148029.51269132615 1.0816849284973642 0.884135023949925 0.8426273824549451 0.8742607582547273 0.7980498128471152 0.9367129689002335 1.088486683729662 0.9474263273137729 0.918791047819025 1.0 17.175525309539424 -7.001334084857725 24.995212496879773 0.9883384438332117 0.8889029794696228 0.22539833519803298 0.08029572846319087 74.36265365756748 1393275.2567764807 0.029283168517880497 0.025482986271792733 9.969328693789108e-08 7.001334084857725 -0.09943546436358885 CVACQNPDKPSPS(ph)TSVPAPASFK ddPTM_PC-9_Lapatinib_30min_R1 2 CVACQNPDKPSPSTSVPAPASFK 23 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 CVACQNPDKPS(0.019)PS(0.425)T(0.425)S(0.131)VPAPAS(0.001)FK;CVACQNPDKPS(0.028)PS(0.598)T(0.187)S(0.187)VPAPASFK 88.555 1.1845e-05 32762000.0 111673.0 110918.0 125632.0 107395.0 130654.0 127798.0 118645.0 107258.0 133214.0 106736.0 True False 110080.52254168005 110661.17618578144 115303.02191354413 115293.18655921772 122969.18859564715 122332.3774516885 124787.85756555638 112241.59824457963 118210.03651439087 125185.17538322012 0.8793415211082198 0.8839798789834544 0.9210597146233611 0.9209811481773238 0.9822983290090913 0.9772113756856707 0.996826159196187 0.8966045532227176 0.9442814307087339 1.0 16.93370420070554 -5.690932890014362 1.5003602654499926 0.9623144918066464 0.8804116981133551 0.5544555332925759 0.02943176757263118 0.3507571830147893 1.5717394428646458 0.010093549178017124 0.025333192954633835 2.0373568789135537e-06 5.690932890014362 -0.08190279369329134 CVEDPETGLCLLPLTDK ddPTM_PC-9_Lapatinib_30min_R1 1 CVEDPETGLCLLPLTDK 17 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 170.07 4.0538999999999995e-24 0.0 6945.8 7441.6 8215.9 6648.8 7651.8 6304.8 6396.4 5127.1 5879.5 4667.9 False True 6846.751618296278 7424.36943241054 7540.4204162911365 7137.77493174661 7201.736168017611 6035.158401206635 6727.574294174434 5365.3237833987705 5217.288796120236 5474.740295414221 1.2506075628886522 1.3561135381397684 1.3773110703729967 1.3037650274891375 1.3154479992502959 1.1023643269913341 1.2288389825193384 0.9800143009327583 0.952974664476846 1.0 12.418574814050865 -7.335989094729059 0.9113320407715062 0.9578250862196969 1.3337969079226597 0.8208549875532833 0.06563726368159345 0.22785764202216724 0.36193301775283643 0.05103589244459923 0.027914724841556708 4.613291585351086e-08 7.335989094729059 0.37597182170296284 CVPAPGAGAS(ph)GGTSPSATQPNPAVFIFEHK ddPTM_PC-9_Lapatinib_30min_R1 1 CVPAPGAGASGGTSPSATQPNPAVFIFEHK 30 0 O60343-2;O60343-3;O60343 O60343-2 TBC1D4 TBC1 domain family member 4 1 CVPAPGAGAS(0.26)GGT(0.25)S(0.216)PS(0.216)AT(0.058)QPNPAVFIFEHK 79.558 6.9402e-07 5572800.0 37346.0 32412.0 41805.0 35175.0 45637.0 46871.0 43878.0 36679.0 49820.0 39190.0 True False 36813.439191582394 32336.95200538734 38367.954271966664 37761.88684036019 42952.72138579415 44866.43659163753 46149.7881432971 38383.24024327272 44208.74697214219 45963.93928260746 0.8009200204803253 0.7035287338312077 0.8347403392921311 0.8215546236840737 0.9344873841578514 0.9761225276140503 1.0040433623312168 0.8350729037229573 0.9618137100983981 1.0 15.488214827227566 -6.026559880870636 1.5943403320793388 0.9501336147379424 0.7613800654108882 0.6945811662801962 0.05330815161304781 0.2212070257509086 1.1324880132836415 0.01846902995583404 0.03071439954959673 9.406761199184954e-07 6.026559880870636 -0.18875354932705424 CVPAPGAGASGGT(ph)SPSATQPNPAVFIFEHK ddPTM_PC-9_AZD4547_30min_R2 1 CVPAPGAGASGGTSPSATQPNPAVFIFEHK 30 0 O60343-2;O60343-3;O60343 O60343-2 TBC1D4 TBC1 domain family member 4 1 CVPAPGAGAS(0.097)GGT(0.269)S(0.269)PS(0.269)AT(0.097)QPNPAVFIFEHK 65.223 0.00034806 15370000.0 13333.0 12055.0 21861.0 20319.0 22352.0 17089.0 20298.0 25405.0 21189.0 20116.0 True False 17572.61665637182 15951.543001626469 21571.10885627636 15634.768475420622 19248.81062360461 16020.42212852 22104.48267756366 21479.240998822945 22309.007281799153 19411.74496283387 0.905256930276836 0.821746990400277 1.1112400712855468 0.805428286089441 0.9916064042907418 0.825295312667307 1.1387169324491624 1.1065074798761032 1.1492530591408676 1.0 14.24464219034055 -7.272200506635395 24.824891661684678 1.1074950037127338 0.9141701691369541 0.4925479174297105 0.0935161227642524 539.7679366390977 1245187.608067534 0.03669402930013266 0.025026858487297323 5.343176167674905e-08 7.272200506635395 -0.19332483457577965 CVPAPGAGASGGT(ph)SPSATQPNPAVFIFEHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CVPAPGAGASGGTSPSATQPNPAVFIFEHK 30 0 O60343-2;O60343-3;O60343 O60343-2 TBC1D4 TBC1 domain family member 4 1 CVPAPGAGAS(0.088)GGT(0.325)S(0.287)PS(0.287)AT(0.014)QPNPAVFIFEHK 76.777 4.182300000000001e-06 4879000.0 57747.0 55259.0 50646.0 70678.0 75806.0 58674.0 72227.0 74352.0 69365.0 51367.0 True False 67522.42654476069 60744.74832599161 51853.59271602458 66718.14080116758 60952.35847792426 55597.032150326224 65385.13568180351 72400.3387824558 70379.3318993126 60679.43047905173 1.1127729118695562 1.0010764413315059 0.8545497593937689 1.0995182432406083 1.0044978668507238 0.9162418254653841 1.0775502532835461 1.1931611455623412 1.1598548526853685 1.0 15.888919924447125 -7.51532796537778 21.754765754577274 1.1329760503268733 0.9966418626855581 0.2867773987675334 0.08534226972617472 72.62147475419177 209243.26449273867 0.03804644331560906 0.023269373141022228 3.052615004827621e-08 7.51532796537778 -0.13633418764131522 CVPAPGAGASGGTS(ph)PSATQPNPAVFIFEHK ddPTM_PC-9_AZD4547_30min_R2 1 CVPAPGAGASGGTSPSATQPNPAVFIFEHK 30 0 O60343-2;O60343-3;O60343 O60343-2 TBC1D4 TBC1 domain family member 4 1 CVPAPGAGAS(0.005)GGT(0.174)S(0.582)PS(0.109)AT(0.13)QPNPAVFIFEHK 105.91 3.0273000000000005e-15 10027000.0 47861.0 42951.0 56494.0 73876.0 55677.0 61619.0 66012.0 81224.0 63511.0 67339.0 True False 63079.80242935661 56834.07079741669 55744.85264747611 56845.02957282221 47947.20960497645 57765.95418908504 71886.94011781107 68672.69714183798 66868.06179972373 64981.48210639645 0.9707350522734131 0.874619490893733 0.8578575132559014 0.8747881354837038 0.737859587851056 0.8889602440046355 1.1062680903477713 1.0568041065822071 1.0290325740837722 1.0 15.987741028774918 -7.177825807061628 5.7939112821528225 1.0522394318362616 0.8600503843446894 0.6960223898774138 0.05847839496981587 0.1280091974912362 6.960834816520667 0.02334069275867242 0.01795011867504618 6.640093472043904e-08 7.177825807061628 -0.19218904749157217 CVPAPGAGASGGTS(ph)PSATQPNPAVFIFEHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CVPAPGAGASGGTSPSATQPNPAVFIFEHK 30 0 O60343-2;O60343-3;O60343 O60343-2 TBC1D4 TBC1 domain family member 4 1 CVPAPGAGAS(0.015)GGT(0.197)S(0.73)PS(0.055)AT(0.003)QPNPAVFIFEHK 116.13 1.1312e-08 0.0 22410.0 19372.0 21350.0 23192.0 26513.0 20632.0 19506.0 23103.0 21810.0 17149.0 True False 26203.570382324393 21295.124134912126 21859.064970325897 21892.627429478493 21317.96797516299 19550.021599439795 17658.250468789498 22496.570729651918 22128.92998953374 20257.97794859069 1.2934938743058177 1.0511969254262905 1.0790348881708893 1.0806916408457006 1.052324572040816 0.9650529608163511 0.8716689549964659 1.1105042559895255 1.0923563075096152 1.0 14.30620255817388 -1.7763601892351468 1.0489293025564903 1.0228987055014829 199.9967337302248 0.5635053158443253 0.06838124802346145 1007.8726742276903 1.9912048433363516 0.023409578471646514 481344.8087648491 0.016735543106385736 1.7763601892351468 198.97383502472331 CVRICSKSY(ph)LT(ph)LENGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 CVRICSKSYLTLENGK 16 2 C9J342;F8WAV2;C9JZG6;F8WDC0;A0A140TA42;A0A0G2JKF9;Q9UBS5-5;Q9UBS5-4;Q9UBS5 C9J342 GABBR1 Gamma-aminobutyric acid type B receptor subunit 1 2 CVRICS(0.087)KS(0.087)Y(0.828)LT(0.997)LENGK 56.147 0.022946 10933000.0 21529.0 16565.0 19211.0 25096.0 31529.0 23800.0 23449.0 28827.0 22507.0 18984.0 True False 25173.434482867557 18209.463725728845 19669.063098123213 23689.952482329758 25351.118782820282 22551.88610249453 21227.74096394159 28070.321794731215 22836.122295939298 22425.64892273868 1.122528697813633 0.8119927226393525 0.8770788825726954 1.0563775685576315 1.1304519601711633 1.0056291427815873 0.9465831306409839 1.2517061107769805 1.0183037456180104 1.0 14.452862112032745 -5.7838468553770355 16.48145954567333 1.0650673679320088 0.9246815342205811 0.2041628052469161 0.10829818844674602 6.639873758032525 4883.4851629071545 0.030148273969092053 0.044930238378874866 1.64495167784e-06 5.7838468553770355 -0.14038583371142777 CVS(ph)VQTDPTDEIPTKK ddPTM_PC-9_AZD4547_30min_R2 2 CVSVQTDPTDEIPTKK 16 1 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;P18583-8 P18583-10 SON Protein SON 1 CVS(0.541)VQT(0.432)DPT(0.015)DEIPT(0.012)KK;CVS(0.943)VQT(0.057)DPTDEIPTKK 74.77600000000001 0.005906000000000001 15025700.0 50369.0 37142.0 55434.0 83983.0 71261.0 55518.0 52160.0 58914.0 48478.0 60696.0 True False 66385.29425971597 49147.42514860309 54698.90894006782 64622.01687441555 61367.640204397336 52046.45068354929 56802.13895269095 49810.195009039795 51040.44811020146 58571.05151442457 1.1334147593946977 0.8391077823914314 0.9338898231423566 1.1033098297458563 1.0477469435440139 0.8886036589377528 0.9697988594024475 0.8504234382196946 0.8714278946764595 1.0 15.83790017464616 -6.770487557912722 24.984831169116774 0.9100614803380539 1.002706382508782 0.2218362416128703 0.08826199576989668 328.7285515095561 907715.6870062738 0.0317257020830242 0.028366452067146556 1.6963381998971364e-07 6.770487557912722 0.09264490217072818 CVWS(ph)PLASPSTSILK ddPTM_PC-9_AZD4547_30min_R2 1 CVWSPLASPSTSILK 15 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 CVWS(0.998)PLAS(0.001)PSTSILK 124.78 2.8281999999999998e-05 3229100.0 8676.8 8702.0 12993.0 13696.0 17560.0 10299.0 8128.9 12542.0 9955.9 11198.0 True False 11435.841911348307 11514.751323115179 12820.70433052461 10538.598801090646 15122.097107663596 9655.00190190341 8852.35635223407 10603.922086488385 10482.148548627321 10805.961428405924 1.0582900917346048 1.0655924879433716 1.1864473527383206 0.9752578584435388 1.3994217180816255 0.8934884661463851 0.8192104340631496 0.9813029739874479 0.9700338667758532 1.0 13.399539816974757 CVWS(ph)PLASPSTSILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 CVWSPLASPSTSILK 15 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 CVWS(0.999)PLAS(0.001)PSTSILK;CVWS(0.981)PLAS(0.015)PS(0.003)T(0.001)SILK 161.94 0.00031127 5892300.0 24133.0 32858.0 32366.0 30911.0 38501.0 24486.0 32424.0 31722.0 28428.0 19707.9 True False 28218.24025152318 36119.92508904309 33137.72818873855 29179.15688481412 30957.00543174104 23201.91105486055 29352.56399056857 30889.33111223728 28843.705719507805 23280.786262349455 1.2120827850715146 1.5514907736366947 1.4233938585798582 1.2533578787243853 1.3297233642751083 0.9966120041393763 1.260806385995589 1.3268164899650594 1.238948951056473 1.0 14.506852162780062 -6.046631943107085 1.9292046134932648 1.1978540229649615 1.4084450047630788 0.3121933898446423 0.13391812899611305 0.4187713530669506 3.1105480904440665 0.04367658190008022 0.06747947701815488 8.981896719025894e-07 6.046631943107085 0.2105909817981173 CVWSPLAS(ph)PSTSILK ddPTM_PC-9_AZD4547_30min_R2 2 CVWSPLASPSTSILK 15 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 CVWS(0.368)PLAS(0.613)PS(0.013)T(0.006)S(0.001)ILK;CVWS(0.219)PLAS(0.622)PS(0.129)T(0.026)S(0.004)ILK 107.13 0.00087105 9810400.0 46829.7 50957.0 68598.0 71834.0 79236.0 71408.0 70394.0 84894.0 68654.0 74227.0 True False 61720.57048172917 67427.85373155368 67688.3456988631 55273.78112423662 68235.44911291754 66942.8464716109 76658.92962875229 71775.58297004808 72282.91028008107 71628.33532294034 0.8616781362216298 0.9413572635403495 0.9449939802968533 0.7716747970622477 0.952632066699222 0.9345860987805363 1.0702319031027487 1.0020557178446752 1.0091384918299375 1.0 16.12824279306065 -6.915674299168151 2.271970654488365 1.0193133202915674 0.8902707235520977 0.5549338447439632 0.05299159500522275 0.2352037861911386 2.467763082467245 0.0218249700493333 0.018220517938224583 1.214299177450526e-07 6.915674299168151 -0.12904259673946972 CVWSPLAS(ph)PSTSILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 CVWSPLASPSTSILK 15 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 CVWS(0.052)PLAS(0.664)PS(0.271)T(0.01)S(0.003)ILK;CVWS(0.017)PLAS(0.522)PS(0.431)T(0.024)S(0.007)ILK 203.53 9.682e-13 7400800.0 31766.0 37672.0 36760.0 39268.0 42524.0 37454.0 49972.0 44808.0 36499.0 34944.0 True False 37143.35639290125 41411.82719442544 37636.497813076334 37067.941268573675 34191.7274610882 35489.84630600126 45238.290394050455 43631.83747800037 37032.72882567594 41279.0705834482 0.899810869477152 1.0032160755826336 0.9117573937860791 0.8979839115718106 0.8283066207115178 0.8597540061919837 1.0959134921073004 1.0569966053328625 0.8971308777607283 1.0 15.33312286775865 -7.250058843670495 24.967192808530726 1.0172599636361015 0.9019886643296737 0.4297299272371147 0.06330110410629051 735.368298453775 1613290.3017498034 0.02589292250628664 0.019869701849613924 5.6226513728701245e-08 7.250058843670495 -0.11527129930642777 CVWSPLAS(ph)PSTSILK ddPTM_PC-9_Lapatinib_30min_R1 1 CVWSPLASPSTSILK 15 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 CVWSPLAS(0.983)PS(0.013)T(0.003)S(0.001)ILK 110.84 0.00048436 4510200.0 28992.0 44830.0 47356.0 48138.0 37502.0 56347.0 55917.0 56608.0 59468.0 41471.0 True False 28578.56876351834 44726.198889347 43462.57247944635 51678.2291036605 35296.20609176879 53937.1701612724 58812.10865601771 59238.21433766406 52770.08761419819 48639.207093366014 0.5875623899184865 0.9195503290892931 0.8935707441944358 1.0624809118384864 0.7256739614199612 1.1089237136974008 1.2091502343597864 1.2179107735854449 1.0849290267602985 1.0 15.569832089996394 -6.863340136857883 6.7535115837026085 1.1472541815518151 0.8586039111372407 0.5385363784390647 0.13132853115202994 0.1742481464297468 10.079828906413317 0.04611012402284791 0.04071071051304858 1.3698085200454848e-07 6.863340136857883 -0.2886502704145745 CYEMASHLR ddPTM_PC-9_AZD4547_30min_R2 6 CYEMASHLR 9 0 P07737;K7EJ44;CON__P02584 P07737 PFN1 Profilin-1 0 ;;;;; 90.15 0.005967899999999999 91324300.0 178466.0 169877.0 219951.0 282389.0 250295.0 231067.0 204496.0 249905.0 198552.0 211951.0 False True 235214.47567659538 224786.41812420596 217034.30602656965 217288.5789165587 215545.85965618814 216618.3439622406 222695.74783875557 211287.9244956055 209047.05336805794 204530.66000286362 1.150020616338412 1.0990353139282822 1.0611333578228856 1.062376559648888 1.053855982536654 1.0590996184103045 1.08881351986855 1.0330379048923388 1.0220817424885398 1.0 17.641957599846187 -1.5228787452803376 0.3747398975153065 1.035343052969975 2.504670229487509 0.7319531156736965 0.02082621429567155 39.31862782380959 0.5402496331985644 0.017204142692085873 41.76066351884795 0.029999999999999995 1.5228787452803376 1.469327176517534 CYEMASHLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 CYEMASHLR 9 0 P07737;K7EJ44;CON__P02584 P07737 PFN1 Profilin-1 0 ;;; 89.88600000000001 0.0061066 60321500.0 183727.0 195049.0 176633.0 235104.0 245821.0 175944.0 224419.0 208700.0 205375.0 154349.0 False True 214828.3523263416 214412.1756860664 180844.6006043825 221931.88509745194 197654.1396908132 166717.18690828976 203160.40766714193 203221.84613592803 208378.2208436723 182331.2518739885 1.1782311047522027 1.1759485742699196 0.99184642646652 1.217190595778018 1.0840387353201224 0.9143642968212063 1.1142379903558646 1.1145749510697007 1.1428552083198835 1.0 17.476202337291724 -5.160194314736788 11.921855915640695 1.0779286339351504 1.1774968565139061 0.20628744896033124 0.08157560081428426 1.1885376554247287 135.2067007823354 0.021033605165955364 0.05572045458823086 6.915214968438844e-06 5.160194314736788 0.09956822257875575 CYEMASHLR ddPTM_PC-9_Lapatinib_30min_R1 8 CYEMASHLR 9 0 P07737;K7EJ44;CON__P02584 P07737 PFN1 Profilin-1 0 ;;;;;;; 100.48 0.0026337 100414000.0 330780.0 412875.0 411228.0 385395.0 412947.0 424739.0 400364.0 394242.0 420034.0 349297.0 False True 326063.016542377 411919.01330446446 377418.42122598476 413738.2339400315 388658.2693450392 406573.903084968 421092.88892390294 412559.9225711793 372725.3477658928 409672.5210410027 0.7959113677281335 1.0054836293577936 0.9212685787832234 1.0099242997521474 0.9487047565636938 0.9924363539244445 1.0278768218426766 1.0070480722574204 0.9098129081705922 1.0 18.644111601115398 -4.756700366970194 24.999343214225366 0.980466416001699 0.7959110883590017 0.6787791771527635 0.03804985148211018 83.3085668178755 439418.91603734903 0.009213384808913773 0.07292705929407525 1.7510543778720518e-05 4.756700366970194 -0.18455532764269733 CYS(ph)QNSSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 CYSQNSSLR 9 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 CY(0.01)S(0.794)QNS(0.098)S(0.098)LR;CY(0.01)S(0.794)QNS(0.098)S(0.098)LR 60.43600000000001 0.039689 1473910.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 398.12 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 387.66977184300805 0.0 0.0 0.0 DADAGDEDEESEEPR ddPTM_PC-9_AZD4547_30min_R2 2 DADAGDEDEESEEPR 15 0 Q9NZT2-2;Q9NZT2;A0A087X028 Q9NZT2-2 OGFR Opioid growth factor receptor 0 ; 253.42 3.7809e-49 4778200.0 7536.4 6898.9 6391.5 9855.9 8950.1 7903.700000000001 4648.7 8311.7 6055.700000000001 7857.299999999999 False True 9932.818433141872 9128.834509657476 6306.744533868091 7583.774527137071 7707.5331049715305 7409.48038955957 5062.425294274815 7027.3177488650535 6375.791939043428 7582.218318575986 1.310014828880231 1.2039793799253145 0.8317809206860927 1.0002052444938538 1.0165274568906215 0.9772180222517177 0.6676707371867905 0.9268155378286248 0.8408874119890634 1.0 12.88840428200319 -5.143085486025574 4.198410427202423 0.9064473644365132 1.2873693460057374 0.6564165431359974 0.10200936900070792 0.1368749414773398 3.9594504066925227 0.0275118455655304 0.08294425059161996 7.193073764323722e-06 5.143085486025574 0.3809219815692242 DADAGDEDEESEEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DADAGDEDEESEEPR 15 0 Q9NZT2-2;Q9NZT2;A0A087X028 Q9NZT2-2 OGFR Opioid growth factor receptor 0 ; 236.08 2.8366999999999995e-31 6241500.0 8466.5 9230.5 7977.5 9956.3 10462.5 9046.9 9403.2 7480.099999999999 8225.4 8116.2 False True 9899.711229002649 10146.843037750692 8167.713854837221 9398.480789760117 8412.448230684675 8572.464637842759 8512.46082272743 7283.755300821069 8345.680914072032 9587.60281219615 1.0325533319350144 1.0583295153657333 0.8519036525425602 0.9802743160995931 0.8774297804643524 0.8941197091454332 0.8878612297016456 0.7597055743230816 0.8704658586248171 1.0 13.226954428031268 -4.943831106639817 0.7222070848242368 0.8681996933763276 1.1482748725634027 0.3897058936929969 0.06904805873658465 2.255722721566523 1.039545749669949 0.029042327586976523 0.496627068953802 1.1380697852521175e-05 4.943831106639817 0.28007517918707503 DADAGDEDEESEEPR ddPTM_PC-9_Lapatinib_30min_R1 2 DADAGDEDEESEEPR 15 0 Q9NZT2-2;Q9NZT2;A0A087X028 Q9NZT2-2 OGFR Opioid growth factor receptor 0 ; 176.99 0.0002229 5701700.0 8035.4 8274.8 9048.3 7671.1 7375.5 9288.4 6277.1 7102.0 9009.2 4987.0 False True 7920.8137224881075 8255.640209002191 8304.383701448056 8235.258284039437 6941.68759079091 8891.15678431794 6602.0975239138115 7431.984847125674 7994.489024918175 5848.996305240194 1.3542175971955641 1.4114627156809543 1.419796366430946 1.4079780280697665 1.1868168876379286 1.5201166696501816 1.1287573421783332 1.2706427666003584 1.3668138271442924 1.0 12.513973362403107 -13.939329126010012 0.14669968299842684 1.8301776806949636e-10 1.4559597789725334 0.5022891282443573 0.10625524219579616 90.56299552395849 0.9313279841816741 26.963046825639204 0.5680831146637101 1.1499285960179171e-14 13.939329126010012 1.4559597787895155 DADDAVYELNGK ddPTM_PC-9_AZD4547_30min_R2 2 DADDAVYELNGK 12 0 Q08170;A0A0D9SEM4;Q13247-3;Q13247;A0A590UJK4;A0A590UK01;A0A590UJP7;A0A590UK80;Q13247-2 Q08170;Q13247-3 SRSF4;SRSF6 Serine/arginine-rich splicing factor 4;Serine/arginine-rich splicing factor 6 0 ; 143.97 0.00010153 2234600.0 24902.0 32139.0 33790.0 32579.0 31719.0 35407.0 39288.0 43602.0 34460.0 33771.0 False True 32820.318006222966 42527.30323760044 33341.9225220062 25068.414890532444 27315.364359793948 33192.994692755994 42784.55588905904 36864.31277428375 36281.48524851566 32588.68756909239 1.0071076945531938 1.3049713385185226 1.0231133871628566 0.769236712505959 0.8381854685581219 1.0185434630462609 1.312865263393932 1.131199674614894 1.1133153236562239 1.0 14.992083631727546 -7.026902872053402 24.452271183806953 1.1524821203930733 0.9890947052707816 0.18617498375431096 0.14944278192795965 999.4817387568197 908435.1738281385 0.06297879815197957 0.04894586224566344 9.399334988275013e-08 7.026902872053402 -0.1633874151222917 DADDAVYELNGK ddPTM_PC-9_Lapatinib_30min_R1 2 DADDAVYELNGK 12 0 Q08170;A0A0D9SEM4;Q13247-3;Q13247;A0A590UJK4;A0A590UK01;A0A590UJP7;A0A590UK80;Q13247-2 Q08170;Q13247-3 SRSF4;SRSF6 Serine/arginine-rich splicing factor 4;Serine/arginine-rich splicing factor 6 0 ; 161.19 0.00037012 8157100.0 42574.0 61681.0 57838.0 48977.0 61612.0 60494.0 68096.0 67007.0 50419.0 58958.0 False True 41966.8869528846 61538.18143416935 53082.782901136416 52578.93196248246 57988.10329385261 57906.81263840162 71621.67768371309 70120.38984108 44740.2812843926 69148.81174340322 0.606906841850225 0.8899383790212431 0.7676600879002162 0.7603736150606879 0.8385986950727995 0.837423105017071 1.0357615102553919 1.014050539310525 0.6470144628141179 1.0 16.077416839795376 -6.737261996476754 2.04352500977256 0.9233127533217459 0.7689746825888961 0.25701400720645584 0.12186001874509637 0.4737191635371397 4.072095943643101 0.04756225023771639 0.04443981227460384 1.831209376902297e-07 6.737261996476754 -0.15433807073284977 DADLS(ph)PVNASIIK ddPTM_PC-9_AZD4547_30min_R2 1 DADLSPVNASIIK 13 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 DADLS(0.997)PVNAS(0.003)IIK 158.65 7.1024e-05 4314000.0 40989.0 58477.0 44573.0 37296.0 40025.0 57969.0 54341.0 69062.0 57267.0 49136.0 True False 54022.649375836205 77378.54666993859 43981.932896519196 28697.983417455973 34468.2196317902 54344.18926608786 59177.24372753409 58390.05478688097 60294.01670710237 47415.76359583442 1.1393394364861018 1.6319160718258783 0.9275803986078399 0.6052414058344334 0.7269358757056548 1.1461207232537771 1.2480499994042686 1.2314481589833697 1.2716027779503973 1.0 15.53307914923764 -6.985182700850839 24.982335333975918 1.2056373302023555 1.0065416960783502 0.09653138291075047 0.26519573133733015 622.2516768988148 1049127.6009917401 0.10613451140208753 0.09356975285858571 1.03470679025192e-07 6.985182700850839 -0.19909563412400533 DADLS(ph)PVNASIIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DADLSPVNASIIK 13 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 DADLS(1)PVNASIIK 103.79 0.0014109 3081700.0 18160.0 26557.0 16663.0 20537.0 21707.0 14948.0 20637.0 12680.0 18346.0 11038.0 True False 21234.129323650654 29193.403450901373 17060.30911477941 19386.37847185234 17453.669175003328 14164.100565549928 18682.11396105857 12347.163435570536 18614.275542777923 13039.102023240079 1.6284962941316259 2.238912112112389 1.3083960141098816 1.4867878506740166 1.3385637403476867 1.0862788357898208 1.4327761166191306 0.9469335705452511 1.4275734256546966 1.0 13.670556897030494 -5.335294874160114 7.460485503624077 1.261298240132049 1.9315837938801663 0.5970743698361833 0.22353240395740864 0.1589598128950185 14.17302362487999 0.055313947379048954 0.11615632810095994 4.620671837971688e-06 5.335294874160114 0.6702855537481174 DADLS(ph)PVNASIIK ddPTM_PC-9_Lapatinib_30min_R1 2 DADLSPVNASIIK 13 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 DADLS(1)PVNASIIK;DADLS(1)PVNASIIK 184.48 5.1538999999999996e-05 7196100.0 38249.0 65785.0 59911.0 59131.0 81504.0 64355.0 72707.0 79421.0 70065.0 67907.0 True False 37703.562245992434 65632.67887431839 54985.34884314785 63479.69099523352 76710.09496302938 61602.6866688322 76471.4127019167 83111.18960061514 62173.5418828411 79644.63446961025 0.4733973920161422 0.8240690576508534 0.6903835921819497 0.7970366292465724 0.9631545862929336 0.7734693878510767 0.960157745856636 1.0435252814466442 0.7806369166847575 1.0 16.281289552538922 -4.114395044053609 0.44960208020294706 0.9445520706970439 2.0950463106316728e-12 0.6019727880276304 0.10223075291831074 6.365116350115629 0.6346775168735146 0.06753819722362019 3.6222521147627287 7.68431139992943e-05 4.114395044053609 -0.944552070694949 DADPILISLR ddPTM_PC-9_Lapatinib_30min_R1 1 DADPILISLR 10 0 Q9BR76 Q9BR76 CORO1B Coronin-1B 0 105.1 0.011559999999999999 1549900.0 16267.0 13672.0 17048.0 12987.0 14902.0 14305.0 12612.0 13634.0 14241.0 13732.0 False True 16035.029596997543 13640.343324005185 15646.37924718306 13942.107303361981 14025.493658459247 13693.208496583711 13264.987649010065 14267.48541336406 12637.028615621775 16105.557903260144 0.9956208715844408 0.8469339221862074 0.9714894287527827 0.8656705583939921 0.8708480477798386 0.8502163401499978 0.8236279505924423 0.8858734046385307 0.7846377437855626 1.0 13.975271016695249 -5.854202407564667 8.65077592784714 0.8610771840698532 0.92875850679106 0.18949305060499144 0.06354058503392254 0.40738914666876874 33.810516141250645 0.01656278790042807 0.024641205506325214 1.3989351819881015e-06 5.854202407564667 0.06768132272120675 DAEAEDKT(ph)LRT ddPTM_PC-9_Lapatinib_30min_R1 1 DAEAEDKTLRT 11 2 E5RK88 E5RK88 ST18 1 DAEAEDKT(0.97)LRT(0.03) 93.178 0.030493 2100800.0 2508.8 2417.5 2328.6 1041.4 2295.3 2051.5 2660.3 2220.2 2468.4 1130.4 True False 2473.0240519424265 2411.9024272807565 2137.1514966559403 1117.9880300085604 2160.294966733427 1963.7621272800754 2798.037317052128 2323.3585972385836 2190.3827985956614 1325.7881338366788 1.8653237186440783 1.8192216129593706 1.6119856876914933 0.8432629629692274 1.6294420741885667 1.4812035778274566 2.11047093094349 1.7524358062513732 1.6521363728433327 1.0 10.37263453018457 DAEDAIYGR ddPTM_PC-9_Lapatinib_30min_R1 1 DAEDAIYGR 9 0 Q13242;S4R3G0;H0YIB4 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 0 110.41 0.010615000000000001 6099200.0 39608.0 50045.0 56801.0 51901.0 54493.0 44830.0 44777.0 43667.0 53036.0 43332.0 False True 39043.18265678238 49929.12387725561 52131.04103820069 55717.97267666057 51287.828877360094 42912.72540383416 47095.33396445636 45695.92823422091 47062.52718616085 50821.87846373937 0.7682357251835761 0.9824336562624161 1.0257598226203974 1.0963383165070233 1.0091683036460994 0.8443750349458596 0.9266744045688543 0.8991389066192084 0.9260288798600634 1.0 15.63316208040779 -6.735537855065853 24.9946078340966 0.9134040101707983 0.986129970578749 0.09162061631667384 0.08633747843440553 475.10152144468407 458465.1601815678 0.029581351454365322 0.029571539284899223 1.8384936954770006e-07 6.735537855065853 0.07272596040795065 DAEDALHNLDR ddPTM_PC-9_AZD4547_30min_R2 2 DAEDALHNLDR 11 0 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 0 ; 89.35600000000001 0.010118 3370200.0 50001.0 58148.0 57892.0 44522.0 50627.0 69153.0 62581.0 79769.0 62424.0 52124.0 False True 65900.2779145913 76943.20385388432 57124.31425403919 34258.14075804305 43598.3149356313 64828.85197808793 68150.58776453894 67442.5339592642 65723.60519887824 50299.154625310824 1.310166709669309 1.529711670644382 1.1356913387425782 0.681087803825716 0.8667802721617189 1.2888656372261509 1.35490523195086 1.3408283789590119 1.3066542706029047 1.0 15.618246532500317 DAEDALHNLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DAEDALHNLDR 11 0 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 0 ; 160.72 0.0010356 5375700.0 34555.0 69017.0 56440.0 42237.0 46070.0 31696.0 43414.0 28279.0 30208.0 31400.0 False True 40404.47900764031 75868.55164253704 57785.74364989194 39870.597824201555 37042.91421626218 30033.805962380942 39301.51162985887 27536.706214077236 30649.73485207865 37092.571437736755 1.0892876239508735 2.0453839866532113 1.55787914965374 1.074894413592435 0.9986612623619818 0.8096986754556882 1.059552091065728 0.7423779249249434 0.8263038571894917 1.0 15.17884266550515 -5.837657414400937 3.0171734816120983 0.9031521647751269 1.6246924251976296 0.6112234900789593 0.2340457836085905 0.15114617199889235 2.7720945634154344 0.06597561776923995 0.1089976373657423 1.453257542327765e-06 5.837657414400937 0.7215402604225026 DAEDALHNLDR ddPTM_PC-9_Lapatinib_30min_R1 3 DAEDALHNLDR 11 0 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 0 ;; 166.11 0.00027422 9321000.0 51930.9 99539.0 90558.0 86321.0 109282.0 97236.0 107347.0 110970.0 84663.0 88381.0 False True 51190.35584303929 99308.52356115775 83112.67080398886 92669.33429841472 102854.24761667849 93077.44294818697 112904.90240709494 116126.07131590231 75127.3613990862 103657.5380897201 0.49384113096272664 0.9580443968792883 0.8018005476075579 0.8939951305635427 0.9922505349071061 0.8979322166384505 1.0892107268587727 1.1202858321349496 0.7247650560064451 1.0 16.661465509062822 -4.507258404963953 2.2255769048127987 0.9495212579987312 6.845670103009549e-18 0.5640180203428518 0.11653385137079669 1.5627575686179216 4.143908604162653 0.030804483302768203 3.939226578507925 3.109865418398983e-05 4.507258404963953 -0.9495212579987312 DAEDALHNLDRK ddPTM_PC-9_AZD4547_30min_R2 2 DAEDALHNLDRK 12 1 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 0 ; 70.808 0.011465000000000001 8453200.0 85127.0 89957.0 97607.0 107417.0 98407.0 112139.0 102505.0 114396.0 100801.0 93713.0 False True 112195.61524840354 119033.84104498643 96312.66740471912 82653.67022610652 84744.88667846557 105126.93060273296 111627.74642150289 96718.72675856519 106129.13507067981 90432.13639401711 1.240660894701878 1.316278104128275 1.0650270052791881 0.9139855976196399 0.9371103023512357 1.1624952676633662 1.2343813921981839 1.0695172160608604 1.173577660581523 1.0 16.464547926276346 -5.266890563977731 24.697132853222243 1.0709204609062584 1.2784695066790408 0.42088627182233973 0.09803215382768071 361.0653119356062 1635852.2251098417 0.028505151389945298 0.06218625194585732 5.408906025006455e-06 5.266890563977731 0.20754904577278244 DAEDALHNLDRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DAEDALHNLDRK 12 1 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 0 82.417 0.004815600000000001 4491000.0 43223.0 38328.0 41515.0 49155.0 57088.0 38164.0 52946.0 43081.0 41799.0 38252.0 False True 50539.80020683659 42132.950539072466 42504.87504651425 46401.00471266018 45902.01620963697 36162.61265611771 47930.57158415506 41950.1693980926 42410.23129906103 45186.784797334614 1.1184641800364987 0.932417535968563 0.9406483607353591 1.0268711288216545 1.0158283315688472 0.8002917848284438 1.060721000600651 0.9283725227683619 0.9385538601445845 1.0 15.463613287256265 -4.755458334172418 24.97977603183529 0.9594952066191046 1.1184644418314489 0.3214545849898871 0.06887781719637752 234.36098711150873 978709.4231174572 0.01658682145649025 0.14711440084871985 1.756069361855479e-05 4.755458334172418 0.1589692352123443 DAEDALHNLDRK ddPTM_PC-9_Lapatinib_30min_R1 2 DAEDALHNLDRK 12 1 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 0 ; 80.916 0.005464699999999999 11560600.0 138597.0 126206.0 129298.0 118407.0 132471.0 142761.0 128483.0 114144.0 139774.0 111251.0 False True 136620.58136442304 125913.77776107349 118667.61754471344 127115.04577417314 124679.31622800678 136655.44482214516 135135.22106785263 119447.54694315864 124031.18023452829 130480.5871173608 1.047056764402352 0.9650000857814988 0.9094656926855933 0.9742065741920634 0.9555392030529716 1.047323957082063 1.0356729997413732 0.9154430523501669 0.950571904792001 1.0 16.99347565324087 -4.758222345837506 24.427427574347778 0.971791305128432 1.0470569055794061 0.21314917338883488 0.04290424182800596 118.50862102881597 899651.5498764005 0.011506356384540674 0.07980408912175498 1.7449285727473584e-05 4.758222345837506 0.07526560045097408 DAEDAVYGR ddPTM_PC-9_Lapatinib_30min_R1 1 DAEDAVYGR 9 0 J3KTL2;Q07955;Q07955-3;Q07955-2 J3KTL2 SRSF1 Serine/arginine-rich splicing factor 1 0 109.11 0.011015 7647500.0 49830.0 47262.0 43579.0 44729.0 49375.0 51335.0 52613.0 54282.0 43986.0 47898.0 False True 49119.41506229716 47152.56774276862 39996.102839804706 48018.519871569886 46470.859574984934 49139.52171772978 55337.04370261387 56804.139886183584 39031.83348688572 56177.10547992678 0.8743671401839762 0.8393555940616625 0.711964464849406 0.854770274497818 0.8272206119909455 0.8747250556596998 0.9850461897220197 1.0111617428648199 0.6947996546534885 1.0 15.777694671202525 -6.911712877331899 3.3639716150226033 0.9244627039610874 0.8178887798505581 0.20707484779109897 0.09284099084318494 0.3838284943927986 8.64032999049606 0.03469493043050165 0.029888713825151316 1.2254260905748725e-07 6.911712877331899 -0.10657392411052935 DAEDDGEEEDD ddPTM_PC-9_AZD4547_30min_R2 2 DAEDDGEEEDD 11 0 H0YCE2;Q5TB25;Q5TB19;Q9BTT0-3;Q9BTT0-2;Q9BTT0 H0YCE2 ANP32E Acidic leucine-rich nuclear phosphoprotein 32 family member E 0 ; 183.26 0.0064194000000000005 11229800.0 72866.0 75864.0 80156.0 110285.0 84871.0 86612.0 78153.0 90987.0 78638.0 81114.0 False True 96035.87229304659 100385.55439862226 79093.07906700004 84860.49713626469 73088.12663009799 81196.13794811715 85108.46559757758 76927.04982325951 82794.64413734106 78274.22354918023 1.226915681031401 1.282485470271696 1.0104613687711042 1.0841435825032013 0.9337445114888456 1.037329203235099 1.0873115278378118 0.9827890502794413 1.0577510754267734 1.0 16.256249671992883 -5.263415416170137 24.994225071170224 1.025211024986075 1.2547005895896433 0.8011581409246782 0.04593269572282242 63.56790895768962 804060.7506832127 0.011569569338473938 0.026210660333005578 5.452360763260326e-06 5.263415416170137 0.22948956460356817 DAEDDGEEEDD ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DAEDDGEEEDD 11 0 H0YCE2;Q5TB25;Q5TB19;Q9BTT0-3;Q9BTT0-2;Q9BTT0 H0YCE2 ANP32E Acidic leucine-rich nuclear phosphoprotein 32 family member E 0 ; 178.83 0.0015435 12719700.0 61671.0 65734.0 64479.0 66681.0 80655.0 69807.0 75526.0 65826.0 62172.0 52926.0 False True 72110.68224222795 72259.63709912826 66016.4238979692 62945.07975271884 64851.23173676196 66146.19803179974 68371.63051911173 64098.1372484121 63081.1478821317 62521.06483801453 1.1533821829340096 1.1557646576613074 1.0559069022418408 1.0067819528634532 1.0372701089590308 1.057982588799112 1.0935775117755175 1.0252246569133716 1.0089583094204855 1.0 15.932054729599127 -5.303338023078809 4.1637074238857235 1.0373639333398434 1.1563696515808035 0.766754910928025 0.026364234883927973 0.09912303848479044 3.805980156966361 0.007420984019860578 0.017676465522385623 4.973498335390539e-06 5.303338023078809 0.11900571824096007 DAEDDGEEEDD ddPTM_PC-9_Lapatinib_30min_R1 2 DAEDDGEEEDD 11 0 H0YCE2;Q5TB25;Q5TB19;Q9BTT0-3;Q9BTT0-2;Q9BTT0 H0YCE2 ANP32E Acidic leucine-rich nuclear phosphoprotein 32 family member E 0 ; 164.72 0.0078641 11365400.0 88623.0 83821.0 82336.0 71825.0 84571.0 81819.0 75238.0 81375.0 82988.0 72952.0 False True 87359.2197685323 83626.91762444683 75566.65190615106 77107.2501011762 79596.70005298321 78319.79209940456 79133.4554976387 85155.97957404287 73641.01753761813 85561.6559975702 1.0210089876125488 0.977387787197827 0.8831836063142235 0.9011893143275058 0.9302847066826713 0.9153608726510472 0.9248705459824895 0.9952586655926944 0.8606777963683804 1.0 16.38467678487104 -5.0227333262648 4.834374771614954 0.9249814832339677 1.0134302139798834 0.3512068076946516 0.04151300251181889 0.1732115468213301 10.997171448259989 0.010076232051194999 0.03402129042135425 9.490010080290104e-06 5.0227333262648 0.08844873074591575 DAEDVDLNHYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DAEDVDLNHYR 11 0 Q15435;B5MBZ8;H7C003;Q15435-3;H7C118;C9JD73;C9J177;Q15435-2;Q15435-5;Q15435-4 Q15435 PPP1R7 Protein phosphatase 1 regulatory subunit 7 0 153.34 2.5053999999999997e-08 0.0 22185.0 33244.0 27908.0 20447.0 27501.0 16420.0 22223.0 14933.0 19788.0 13849.0 False True 25940.482326276953 36544.24461805796 28573.43256167938 19301.420880068414 22112.376467580347 15558.906294242022 20117.876559412925 14541.024572821352 20077.36206478194 16359.714071376311 1.5856317667350668 2.2337948242015675 1.7465728579983397 1.1798140722910948 1.3516358764649288 0.9510500138547398 1.2297205483934506 0.8888312173048905 1.2272440690091395 1.0 13.99785991319511 -5.722453857542195 3.240800088138658 1.1119128011438286 1.9298622324641146 0.7499109825462933 0.1966061084896595 0.10617176921481122 2.279528110077051 0.053132563916819066 0.09464108497281913 1.8947248123676752e-06 5.722453857542195 0.817949431320286 DAEFYEHR ddPTM_PC-9_AZD4547_30min_R2 2 DAEFYEHR 8 0 O95340;O95340-2 O95340 PAPSS2 Bifunctional 3-phosphoadenosine 5-phosphosulfate synthase 2;Sulfate adenylyltransferase;Adenylyl-sulfate kinase 0 ; 106.68 0.0027458 0.0 27394.0 22378.0 41676.0 42943.0 36384.0 37369.0 40788.0 49010.0 36531.0 38708.0 False True 36104.722169402965 29611.250874358935 41123.34900938536 33043.15481273625 31332.709633555394 35032.310522597196 44418.05298317405 41436.63063776076 38461.954080485404 37352.844701798254 0.9665856096808819 0.7927441968812988 1.1009428957202176 0.8846221774146554 0.8388306134029723 0.9378753024641965 1.1891477968486737 1.1093299845986269 1.0296927687179271 1.0 15.188930498893184 -7.137935790351012 6.82547082956429 1.0905097747129078 0.9156157810975 0.4367526681771867 0.08998555531272633 0.22664983737488512 11.6649462647171 0.034166199601240343 0.026430618827377125 7.278874134114845e-08 7.137935790351012 -0.1748939936154078 DAEFYEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DAEFYEHR 8 0 O95340;O95340-2 O95340 PAPSS2 Bifunctional 3-phosphoadenosine 5-phosphosulfate synthase 2;Sulfate adenylyltransferase;Adenylyl-sulfate kinase 0 136.27 0.0029298 2864300.0 25378.0 31682.0 30372.0 34556.0 38200.0 35985.0 39590.0 28557.0 26152.0 26736.0 False True 29673.994161652325 34827.17958095631 31096.18366645143 32619.93935206356 30714.984220994458 34097.883252027954 35839.74859322136 27807.40900864256 26534.4235252768 31583.025157940447 0.9395551570268701 1.1027182927155488 0.9845853432641611 1.03283137663152 0.9725155860591224 1.0796268907589188 1.1347788381256667 0.880454258880624 0.840148256621505 1.0 14.946861744899985 -7.785918214576129 24.99916235916248 0.895225823374385 1.03508123974346 0.42468862433055377 0.0680607665077172 206.64209163524512 211031.39034120893 0.03611538443734478 0.017361372681134614 1.637124792299807e-08 7.785918214576129 0.13985541636907484 DAEFYEHR ddPTM_PC-9_Lapatinib_30min_R1 2 DAEFYEHR 8 0 O95340;O95340-2 O95340 PAPSS2 Bifunctional 3-phosphoadenosine 5-phosphosulfate synthase 2;Sulfate adenylyltransferase;Adenylyl-sulfate kinase 0 ; 124.08 0.0027843000000000004 5074700.0 48609.0 57220.0 62142.0 55121.0 52986.0 55661.0 44391.0 47419.0 68387.0 50149.0 False True 47915.82674620114 57087.510605586336 57032.924635056894 59174.78221826565 49869.467654484084 53280.508782128316 46689.34877316883 49622.25985157033 60684.53591296447 58817.18783065786 0.814656880300991 0.9705923168232476 0.969664255272828 1.0060797600292852 0.847872356598629 0.9058663079154626 0.793804506730131 0.8436693708383187 1.031748340088665 1.0 15.843950187240056 -3.265279658927441 15.361722649062818 0.9135939022713337 0.4097105122018698 0.0 0.08353402510937998 0.0 0.0 0.01932437343757755 0.0 0.0005429006243081385 3.265279658927441 -0.5038833900694639 DAEGILEDLQSYR ddPTM_PC-9_Lapatinib_30min_R1 1 DAEGILEDLQSYR 13 0 E5RK61;E5RFS4;E5RHU5;E5RGI7;E5RJE1;E5RIR8;E5RJL8;E5RI16;Q9NUQ9 E5RK61 FAM49B Protein FAM49B 0 153.34 0.00066809 1969400.0 9884.4 8141.6 9997.2 8654.0 10461.0 8107.7 9255.2 7207.0 11533.0 6868.5 False True 9743.446643423034 8122.748625418415 9175.26880630799 9290.444028897715 9845.704547117308 7760.95257097181 9734.388969958598 7541.863530447025 10234.03209212597 8055.71107329904 1.2095079571210117 1.0083217423650623 1.1389768976099162 1.1532742354292278 1.2222017966547074 0.9634099957601236 1.2083835779840217 0.9362132606077219 1.2704070440221047 1.0 12.975796225132697 -6.739264861346922 24.999760373956054 1.0799897811961539 1.1387455419222112 0.0900479641145776 0.11072416742909268 722.3011104673301 814326.5178852777 0.03419095420637568 0.034164962114794487 1.8227837098453957e-07 6.739264861346922 0.05875576072605737 DAELQDQEFGKRDS(ph)LGTYSSR ddPTM_PC-9_Lapatinib_30min_R1 1 DAELQDQEFGKRDSLGTYSSR 21 2 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 DAELQDQEFGKRDS(0.683)LGT(0.186)Y(0.006)S(0.063)S(0.063)R 48.75899999999999 0.016904 170890000.0 142640.0 85996.0 98515.0 79246.0 82392.0 94255.0 62164.0 59935.0 99386.0 69609.0 True False 140605.92744302767 85796.88154557848 90415.47697889715 85074.01519690626 77545.86454890441 90223.93336913658 65382.547749211975 62719.79890347472 88192.10209902305 81640.82290183785 1.7222502474293708 1.0509066236230584 1.1074787559112387 1.0420523969876732 0.9498417800386815 1.1051325814980915 0.8008560598149008 0.7682406506226288 1.0802451391880534 1.0 16.317003103693935 -2.3210637562174474 1.0998583770891537 0.9566478139576674 199.99998540748086 0.7891630075086857 0.11355729679161138 186.78033256406175 1.1460074866810936 0.03578388022156068 92706.32416693485 0.0047745917554033665 2.3210637562174474 199.0433375935232 DAENHEAQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DAENHEAQLK 10 0 Q9Y266;A0A0A0MSS4;A0A0A0MSU9 Q9Y266 NUDC Nuclear migration protein nudC 0 75.566 0.02315 0.0 32068.0 35505.0 35308.0 44720.0 44067.0 36161.0 41005.0 36130.0 33549.0 32651.0 False True 37496.47902812934 39029.70175562953 36149.87662633565 42214.48338419617 35432.38768760638 34264.65350219767 37120.7095495085 35181.62578289934 34039.590656527645 38570.367834826226 0.9721576726647848 1.0119089847099814 0.9372447984199661 1.0944796680440154 0.9186427217739294 0.8883672991902137 0.9624152330741117 0.9121413084148215 0.8825321760554324 1.0 15.235205284161424 DAENHEAQLK ddPTM_PC-9_Lapatinib_30min_R1 1 DAENHEAQLK 10 0 Q9Y266;A0A0A0MSS4;A0A0A0MSU9 Q9Y266 NUDC Nuclear migration protein nudC 0 99.568 0.0036284999999999998 3670000.0 49183.0 46524.0 51271.0 52713.0 56522.0 46531.0 49465.0 43917.0 52005.0 42808.0 False True 48481.64140094245 46416.276536426056 47055.69629178335 56589.689865413144 53197.48708652758 44540.97759905884 52026.05566589617 45957.5441468908 46147.64926307215 50207.3057619255 0.9656292180033349 0.9244924783760384 0.9372280702516375 1.1271206253080344 1.0595566975607298 0.8871413616628738 1.036224805859826 0.9153557126688625 0.9191421161274108 1.0 15.615609688339356 -9.779225888847414 11.530729339391316 1.000001142268261 0.9765527355630661 0.01028149940540779 0.07247935888120229 0.0 0.0 0.07372425734851391 0.017880758836361293 1.6625476873535982e-10 9.779225888847414 -0.02344840670519499 DAEPPS(ph)PTPAGPPR ddPTM_PC-9_AZD4547_30min_R2 2 DAEPPSPTPAGPPR 14 0 O43306-2;O43306 O43306-2 ADCY6 Adenylate cyclase type 6 1 DAEPPS(0.878)PT(0.122)PAGPPR;DAEPPS(0.94)PT(0.06)PAGPPR 137.73 7.5743e-05 15780800.0 32020.0 49931.0 47055.0 58592.0 54269.0 32053.0 45218.0 62804.0 42473.0 41280.0 True False 42201.693942625454 66070.21929607722 46431.01995480919 45084.51963737611 46734.686101127314 30048.720842966333 49242.31440112685 53099.08489234706 44718.03606965197 39834.7997646541 1.0594177501068183 1.6586055330119203 1.165589389908469 1.1317872790559411 1.1732125271681564 0.7543334225475116 1.2361632214057257 1.3329823472455993 1.1225871934551765 1.0 15.281741702572381 -5.4971912727431995 24.54852387674221 1.1172025108759203 1.3722831619893348 0.20030516838301082 0.19732386843692995 866.4743161460246 828053.8392667774 0.051008879754253056 0.1054967480063734 3.1827954406027192e-06 5.4971912727431995 0.2550806511134145 DAEPPS(ph)PTPAGPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DAEPPSPTPAGPPR 14 0 O43306-2;O43306 O43306-2 ADCY6 Adenylate cyclase type 6 1 DAEPPS(0.967)PT(0.033)PAGPPR;DAEPPS(1)PTPAGPPR 158.31 5.0703e-05 11962800.0 59644.0 63267.0 58624.0 42232.0 116244.0 62267.0 51910.0 61366.0 58804.0 49150.0 True False 69740.55117730272 69547.72964296327 60021.818492758066 39865.87795799133 93466.82266453632 59001.60890521122 46992.70900414551 59755.207522651544 59663.8972537617 58060.5059288141 1.2011702285682648 1.1978491838881535 1.0337804938584012 0.686626430828375 1.6098175716748426 1.0162090040612284 0.8093747764058684 1.0291885433433057 1.0276158689852524 1.0 15.825269522954104 -6.986472893113175 24.999861164333737 0.9609505762837983 1.1366006592599531 0.13258048268723643 0.2187474369943085 514.9391299332807 951670.8386527719 0.07821446041323521 0.06894517606006882 1.031637468025042e-07 6.986472893113175 0.1756500829761548 DAEPPS(ph)PTPAGPPR ddPTM_PC-9_Lapatinib_30min_R1 2 DAEPPSPTPAGPPR 14 0 O43306-2;O43306 O43306-2 ADCY6 Adenylate cyclase type 6 1 DAEPPS(0.752)PT(0.248)PAGPPR;DAEPPS(0.767)PT(0.233)PAGPPR 74.133 0.019017 14741900.0 75655.0 79605.0 47624.0 33028.0 49272.0 35949.0 38754.0 30777.0 64585.0 24976.0 True False 74576.14582657223 79420.67951341663 43708.53855395627 35456.98929817813 46373.91783247914 34411.54507121201 40760.49249522166 32207.011776962398 57310.75718979938 29293.06832157191 2.545863239995692 2.7112448119656314 1.492111992985336 1.2104225105045416 1.5831020951235963 1.1747333769699626 1.3914722775969817 1.0994755285927016 1.9564613908197102 1.0 14.838271696715902 -5.296384351454117 5.165792485368011 1.3567400022381897 2.6363797518920773 0.7897788708359696 0.261481996987319 0.0685946639212045 4.963779303922548 0.0638694027864599 0.14462080251155524 5.053772042313475e-06 5.296384351454117 1.2796397496538876 DAEPQPGS(ph)PAAESLEEPDAAAGLSSTK ddPTM_PC-9_AZD4547_30min_R2 1 DAEPQPGSPAAESLEEPDAAAGLSSTK 27 0 Q9H9J4-2;Q9H9J4;C9JPC9 Q9H9J4-2 USP42 Ubiquitin carboxyl-terminal hydrolase 42 1 DAEPQPGS(0.975)PAAES(0.025)LEEPDAAAGLSSTK 85.448 1.8431e-05 0.0 7192.9 10357.0 8409.6 7159.0 7389.5 12919.0 9622.5 13745.0 9319.1 9159.9 True False 9480.09257838572 13704.697707826243 8298.083209264978 5508.6031554474275 6363.595477054683 12111.172887726018 10478.883858747478 11621.026078678271 9811.688600680287 8839.214689056575 1.0725039397586515 1.5504429058379359 0.9387805932056899 0.6232005160217882 0.7199276973024717 1.3701639018588725 1.1854994167887904 1.3147125041623584 1.1100181346231683 1.0 13.109702485214239 -6.781154619477484 24.999914977969013 1.2150870580574786 0.9903882505407929 0.1539837976189441 0.24963873529228217 521.344289417107 661086.2472822671 0.09795533189950636 0.08650353705602729 1.655180573714465e-07 6.781154619477484 -0.2246988075166857 DAEPQPGS(ph)PAAESLEEPDAAAGLSSTK ddPTM_PC-9_Lapatinib_30min_R1 1 DAEPQPGSPAAESLEEPDAAAGLSSTK 27 0 Q9H9J4-2;Q9H9J4;C9JPC9 Q9H9J4-2 USP42 Ubiquitin carboxyl-terminal hydrolase 42 1 DAEPQPGS(0.968)PAAES(0.03)LEEPDAAAGLS(0.001)S(0.001)TK 63.25 0.00044648 1446600.0 7647.1 9972.8 9197.0 10616.0 11133.0 12560.0 10851.0 11312.0 10626.0 12276.0 True False 7538.050951693611 9949.708594327 8440.85816144666 11396.736053937844 10478.178828320148 12022.838078790031 11412.811685649234 11837.596816486299 9429.187983259395 14397.890243258207 0.523552466669434 0.691053232537728 0.5862565986290305 0.7915559753120323 0.7277579319808012 0.8350416537186557 0.7926725022086668 0.8221757921810272 0.6549006711364951 1.0 13.813569805204478 -3.4002794202673803 0.11300803235193829 1.053567678973343 6.885931209499634e-24 0.604404783099371 0.08177251879404901 48.01148785806487 0.5929091390840382 0.8360404133442046 7.757489726027694 0.00039785111518252276 3.4002794202673803 -1.053567678973343 DAETGEEVTHYLVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DAETGEEVTHYLVK 14 0 C9JFU2;H7C294;Q8TD26-3;Q8TD26 C9JFU2 CHD6 Chromodomain-helicase-DNA-binding protein 6 0 62.298 0.020526 1411600.0 16426.0 21250.0 12885.0 16731.0 16483.0 14289.0 20095.0 12602.0 12961.0 15285.0 False True 19206.59737171177 23359.559563642517 13192.22726663462 15793.616312633862 13253.274474205546 13539.659685653127 18191.456124798762 12271.210852922703 13150.530105197022 18056.04950400657 1.063720907912326 1.2937248293686345 0.7306264453754026 0.8746994357281375 0.7340074289929641 0.7498683298718652 1.0074992384553525 0.6796177009926655 0.7283171273029003 1.0 14.14019465861313 -5.2651726612606655 24.999789028530383 0.8056999676743659 1.178722880158471 0.5947386283689825 0.1206089485623478 182.59546883690206 1222752.8521206754 0.030005753005018537 0.0665779647174496 5.430343958821328e-06 5.2651726612606655 0.37302291248410513 DAGDPS(ph)PPNK ddPTM_PC-9_AZD4547_30min_R2 1 DAGDPSPPNK 10 0 Q9BTA9-2;Q9BTA9;A0A0A0MRT2;Q9BTA9-5;Q9BTA9-3;E9PMZ7;C9JMU2;A0A494C0B7;A0A494C0C1;A0A494C0S5;C9JVK6;C9JD58;J3QTA0 Q9BTA9-2 WAC WW domain-containing adapter protein with coiled-coil 1 DAGDPS(1)PPNK 87.667 0.01048 32516000.0 77652.0 67626.0 89770.0 104400.0 102650.0 98144.0 90547.0 100200.0 93407.0 97036.0 True False 102343.72073806233 89484.78200149255 88579.59114532391 80332.19296392107 88398.81936797642 92007.04016510425 98605.50758721818 84716.39236693778 98344.30332583006 93638.79917545976 1.092962763718182 0.9556378636788855 0.9459710283057353 0.8578943095307656 0.9440405061403586 0.9825739007257245 1.0530411373863502 0.9047146387278714 1.0502516498695498 1.0 16.51481881298787 -6.910936928934254 5.481945618424324 0.9971573420101757 0.9530525765714206 0.07986103197843042 0.06579223769836941 0.5641422536581077 27.175715425631495 0.02405154064431086 0.021140765770096995 1.227617500801162e-07 6.910936928934254 -0.04410476543875508 DAGDPS(ph)PPNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DAGDPSPPNK 10 0 Q9BTA9-2;Q9BTA9;A0A0A0MRT2;Q9BTA9-5;Q9BTA9-3;E9PMZ7;C9JMU2;A0A494C0B7;A0A494C0C1;A0A494C0S5;C9JVK6;C9JD58;J3QTA0 Q9BTA9-2 WAC WW domain-containing adapter protein with coiled-coil 1 DAGDPS(1)PPNK;DAGDPS(1)PPNK 86.911 0.010964 33818000.0 224850.0 241340.0 211863.0 246010.0 246070.0 217130.0 249090.0 233090.0 211990.0 168664.0 True False 262912.6640100688 265298.64023950486 216914.61741490234 232226.8572751809 197854.3499282755 205743.3205644808 225494.39194456977 226971.63447926953 215089.95270432185 199241.4480565107 1.3195681248788107 1.3315434254636536 1.0887022732005993 1.165554956262487 0.9930381045622506 1.032633132168995 1.1317644704158794 1.1391788038746522 1.0795442153347332 1.0 17.604158275885965 -5.263242353829918 21.235891568004757 1.0840505621520238 1.325555956830301 0.7637665015742263 0.054830532472459975 8.644245085535317 101833.80396999308 0.014701679442021942 0.033471542985733974 5.454533911631569e-06 5.263242353829918 0.24150539467827725 DAGDPS(ph)PPNK ddPTM_PC-9_Lapatinib_30min_R1 3 DAGDPSPPNK 10 0 Q9BTA9-2;Q9BTA9;A0A0A0MRT2;Q9BTA9-5;Q9BTA9-3;E9PMZ7;C9JMU2;A0A494C0B7;A0A494C0C1;A0A494C0S5;C9JVK6;C9JD58;J3QTA0 Q9BTA9-2 WAC WW domain-containing adapter protein with coiled-coil 1 DAGDPS(1)PPNK;DAGDPS(1)PPNK;DAGDPS(1)PPNK 113.61 0.0012824000000000002 82849000.0 409372.0 404636.0 426015.0 401522.0 410513.0 408510.0 386782.0 370720.0 399191.0 369172.0 True False 403534.2802103685 403699.09020276193 390989.69116545573 431051.2673181275 386367.4324396107 391038.9795833211 406807.6794211391 387945.00457989704 354229.9059124131 432982.8883092305 0.9319866699262485 0.9323673085076876 0.903014187678974 0.9955388052432145 0.8923388033840088 0.9031280222419468 0.939546782113483 0.8959823010438047 0.8181152546135424 1.0 18.723950484517616 DAGEGGLSLAIEGPSK ddPTM_PC-9_Lapatinib_30min_R1 1 DAGEGGLSLAIEGPSK 16 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 184.98 3.2488e-07 5200100.0 21301.0 25580.0 21305.0 19942.0 23115.0 20479.0 23529.0 19985.0 19975.0 19097.0 False True 20997.243833875 25520.771081630508 19553.385139678274 21408.60120456185 21755.42114583851 19603.160908880658 24747.21649171881 20913.576058829436 17725.205153924948 22397.891004847 0.9374652206911404 1.1394274164521876 0.873001173880471 0.9558311182034478 0.971315609185282 0.8752235156711161 1.1048904776955744 0.9337297004572283 0.7913783110244236 1.0 14.451075273435364 -5.273619619065888 24.948829490041906 0.9413250076799806 1.0384463310935856 0.16123286753849342 0.09125782726450601 1178.8006126858543 2414543.8833583547 0.023341819781577337 0.04922346808961175 5.3257451548161745e-06 5.273619619065888 0.09712132341360502 DAGEGLLAVQITDQEGKPK ddPTM_PC-9_Lapatinib_30min_R1 2 DAGEGLLAVQITDQEGKPK 19 1 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 149.95 0.00012321 9325300.0 74891.0 67905.0 60646.0 60936.0 72950.0 68287.0 64642.0 58467.0 63640.0 59718.0 False True 73823.0406066725 67747.77014457069 55659.91998032989 65417.43671653699 68659.22442521818 65366.52419477187 67988.84646426492 61183.590264277205 56472.193041090555 70040.17673076673 1.0540099133451224 0.9672701199054935 0.7946856015838694 0.9339987385811507 0.9802834263132015 0.9332718340509004 0.9707120917985816 0.8735499126375124 0.8062828461751135 1.0 16.09589510364472 -7.773929886056645 24.850110361602496 0.8799372554416091 0.942777111308023 0.08815096438952574 0.075590391347352 488.2726106891993 971411.4743959473 0.04158411992466261 0.020190952431751168 1.682945739488421e-08 7.773929886056645 0.06283985586641394 DAGGPRPES(ph)PVPAGR ddPTM_PC-9_AZD4547_30min_R2 1 DAGGPRPESPVPAGR 15 1 E9PS47;E9PLE4;Q9BVG9 E9PS47 PTDSS2 Phosphatidylserine synthase 2 1 DAGGPRPES(1)PVPAGR 110.6 0.0024614999999999997 10327000.0 13427.0 14482.0 23135.0 22378.0 20547.0 15696.0 18521.0 18840.0 18206.0 16221.0 True False 17696.506701050355 19163.023289054716 22828.214783859534 17219.097836653506 17694.403717036676 14714.526638729589 20169.333120068794 15928.710900130856 19168.33199171435 15653.107727288132 1.1305427017664968 1.2242312276205531 1.458382270254424 1.1000433994736634 1.1304083524698385 0.9400386744338116 1.2885194091463068 1.0176069300514852 1.2245703745012955 1.0 13.93416149406492 -5.890795621436127 23.02782392750156 1.1032988936725239 1.2685355381044583 0.28786317241210513 0.123075917446398 6.5142376566628295 1346.884896216919 0.03350599719665535 0.049697426128131474 1.2858916569491799e-06 5.890795621436127 0.16523664443193442 DAGLLVEQPPLAGVAAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 DAGLLVEQPPLAGVAASPR 19 0 Q13469-3;Q13469-4;Q13469-2;Q13469 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 DAGLLVEQPPLAGVAAS(1)PR;DAGLLVEQPPLAGVAAS(1)PR 220.48 3.2196e-28 22550000.0 40540.0 37747.0 54511.0 79982.0 67298.0 66969.0 94998.0 149964.0 111277.0 97171.0 True False 53430.87671561641 49947.979567183254 53788.148523145355 61543.385609581775 57954.83434803786 62781.417843341085 103452.63796448853 126790.50962989526 117158.87504350214 93769.07286655054 0.5698134265618441 0.5326700802328267 0.573623550695602 0.6563292536460135 0.6180591593404952 0.669532244737983 1.1032703513206252 1.3521570146090691 1.249440476075084 1.0 16.516824547713092 -7.28423224560064 2.9536558934617934 1.228370738683464 0.5923874081376611 0.9101853170663986 0.088637341458945 0.06860661823834598 1.2077645645309623 0.03939370938082151 0.026350807451380784 5.197179950796834e-08 7.28423224560064 -0.6359833305458028 DAGLLVEQPPLAGVAAS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DAGLLVEQPPLAGVAASPR 19 0 Q13469-3;Q13469-4;Q13469-2;Q13469 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 DAGLLVEQPPLAGVAAS(1)PR;DAGLLVEQPPLAGVAAS(1)PR 135.36 3.8466e-05 13986600.0 31569.0 29979.0 56208.0 61171.0 128346.0 95415.0 113583.0 119661.0 92718.0 112817.0 True False 36913.00818382861 32955.11699569121 57548.21189002707 57743.78718905777 103197.52263947007 90411.26943149226 102823.5959702921 116520.0255413096 94073.8253447772 133269.82904111943 0.276979481773323 0.24728115307721413 0.43181725604428434 0.4332847697376527 0.7743502290201726 0.678407634211015 0.7715444426552587 0.874316612992414 0.7058898928710369 1.0 17.023990680073908 -5.800289118636315 0.4633127060108692 0.8990040078797625 0.05019590140407093 0.8799519817750799 0.08440947700355335 0.6392654321451476 0.20614910415890358 0.06684494687501912 0.27210606951449706 1.5838384480709592e-06 5.800289118636315 -0.8488081064756916 down DAGLLVEQPPLAGVAAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 DAGLLVEQPPLAGVAASPR 19 0 Q13469-3;Q13469-4;Q13469-2;Q13469 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 DAGLLVEQPPLAGVAAS(1)PR;DAGLLVEQPPLAGVAAS(1)PR 157.02 1.441e-05 12250000.0 44588.0 30133.0 50778.0 50822.0 77157.0 53624.0 63593.0 52455.0 94726.0 99818.0 True False 43952.16694356223 30063.22888986601 46603.22884874832 54559.61941722206 72618.77695649845 51330.62652364942 66885.53437706137 54892.250796392225 84056.96037099848 117071.40830087545 0.37543041107530234 0.2567939459018296 0.3980752390795304 0.4660370982896433 0.6202947244801822 0.4384557021107055 0.5713225402154934 0.4688783674261288 0.7179973453037373 1.0 16.83702925190577 -14.522878745269006 0.08681582154074319 2.7905924730379983 2.0183281238547827e-11 0.8404053606937545 0.0797217194543911 85.93439620259016 0.5196651817531025 28.44013643369213 2.170412240756708 3.0000000000782754e-15 14.522878745269006 -2.790592473017815 DAGRPGERGS(ph)GGLFSPSTAHVPDGALGQR ddPTM_PC-9_AZD4547_30min_R2 1 DAGRPGERGSGGLFSPSTAHVPDGALGQR 29 2 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 DAGRPGERGS(0.793)GGLFS(0.164)PS(0.007)T(0.036)AHVPDGALGQR 49.208 0.0052409 23619000.0 6968.6 5961.5 20029.0 40809.0 34774.0 34932.0 20762.0 27550.0 21192.0 28158.0 True False 9184.469844115547 7888.438291513576 19763.402373283883 31401.11554276492 29946.230342932482 32747.696517845412 22609.777778676544 23292.78053601936 22312.16585567452 27172.19699062816 0.33800983583636324 0.2903128626012222 0.7273391393452796 1.1556340311236275 1.1020908744795683 1.2051913405875967 0.8320923695082433 0.8572284583411922 0.8211395590636307 1.0 14.729843598011184 -5.432476204547522 3.2905587652894863 0.9955655799554579 0.31389620195107787 0.8158055834783946 0.12834779216787212 0.10785814000124322 2.1989718757733088 0.03944407440344215 0.0904254224607656 3.694228848730704e-06 5.432476204547522 -0.6816693780043801 down DAGT(ph)IAGLNVLR ddPTM_PC-9_AZD4547_30min_R2 1 DAGTIAGLNVLR 12 0 P11142;E9PKE3;P11142-2;E9PN89;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65 P11142 HSPA8 Heat shock cognate 71 kDa protein 1 DAGT(1)IAGLNVLR 111.88 0.0024954 4151100.0 14656.0 17353.0 17152.0 25606.0 20263.0 16673.0 17908.0 19987.0 14957.0 20335.0 True False 19316.3031362623 22962.01789358973 16924.553273082285 19702.932308756368 17449.83221483984 15630.434674282511 19501.777307607143 16898.46840556875 15747.596484679314 19623.077839492275 0.9843666367865811 1.1701537384404448 0.8624820943746605 1.0040694161189834 0.889250522143948 0.7965332860692016 0.99381847573162 0.8611527989538862 0.8025038994130986 1.0 14.26026372261126 -5.272808109784605 24.993718833066836 0.8990805666414835 1.0772601914044988 0.4138913131771981 0.08376078366788176 585.136747493785 1286401.7545692704 0.02119903049558737 0.04477914693802697 5.335705981389076e-06 5.272808109784605 0.1781796247630153 DAGT(ph)IAGLNVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DAGTIAGLNVLR 12 0 P11142;E9PKE3;P11142-2;E9PN89;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65 P11142 HSPA8 Heat shock cognate 71 kDa protein 1 DAGT(1)IAGLNVLR 99.834 0.0078777 1726000.0 6340.7 6956.4 6989.8 8241.9 7656.9 8528.3 9678.0 7810.3 7055.1 7197.4 True False 7414.055275466498 7646.985418754006 7156.463340964113 7780.1330636003195 6156.585410516562 8081.060934785884 8761.22977734772 7605.287900696895 7158.26749056211 8502.231645412943 0.8720128531744333 0.8994092066263152 0.8417158740699697 0.9150695238699824 0.7241140523192066 0.9504635102650625 1.030462370673529 0.8945049038742716 0.8419280712522202 1.0 13.053625850759365 DAGT(ph)IAGLNVLR ddPTM_PC-9_Lapatinib_30min_R1 2 DAGTIAGLNVLR 12 0 P11142;E9PKE3;P11142-2;E9PN89;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65 P11142 HSPA8 Heat shock cognate 71 kDa protein 1 DAGT(1)IAGLNVLR;DAGT(1)IAGLNVLR 129.17 0.00044807 5304600.0 19624.7 19580.3 16566.7 17976.0 20676.0 17577.1 18284.699999999997 19364.8 21434.0 17014.6 True False 19344.848179270786 19534.963018360057 15204.649875311345 19298.015006178117 19459.878330580013 16825.36840722136 19231.39229827579 20264.559302678023 19019.877209973827 19955.5509394706 0.9693968479220543 0.9789237629977606 0.7619258381505106 0.9670499734491457 0.9751611664145948 0.8431422644384139 0.9637114182719718 1.0154848324731656 0.9531121073863174 1.0 14.284502489351773 -7.510917706413736 24.006563972779862 0.9884987253448316 0.9156964125145344 0.2042916066992133 0.06639044792713336 568.1492199836498 1140321.780808397 0.029497382798509473 0.018661377377133033 3.083772232676868e-08 7.510917706413736 -0.07280231283029726 DAGTIAGLNVLR ddPTM_PC-9_Lapatinib_30min_R1 2 DAGTIAGLNVLR 12 0 P11142;E9PKE3;P11142-2;E9PN89;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 ; 123.51 0.0016187999999999999 81660000.0 149096.0 158578.0 173119.0 160286.0 164143.0 187584.0 157113.0 141993.0 178853.0 151167.0 False True 146969.8636991424 158210.82238400358 158885.82407866526 172073.96713842172 154488.43145755437 179561.46959966165 165247.54238018682 148590.51315093163 158708.69173441504 177296.01453263362 0.8289518751257137 0.8923540825272349 0.8961612842651929 0.9705461659249497 0.8713587378983004 1.0127778115768702 0.9320431867337372 0.8380927994497114 0.8951622074121844 1.0 17.435800580449893 -4.676307839902439 1.398866025218534 0.9250559964452252 0.7724843899381358 0.2527608954165901 0.05231795469087407 2.443546971181912 3.624067318292084 0.015361507981302655 0.5649003728765384 2.107134025765689e-05 4.676307839902439 -0.15257160650708934 DAGVIAGLNVLR ddPTM_PC-9_Lapatinib_30min_R1 2 DAGVIAGLNVLR 12 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 ; 117.71 0.0028495 30786000.0 75020.0 69289.0 71238.0 69143.0 67848.0 66031.0 72769.0 55828.0 64727.0 65741.0 False True 73950.20104301679 69128.56557760361 65381.086626632256 74228.00687428653 63857.31403430037 63207.008055778955 76536.62275854847 58421.9726901341 57436.76365447304 77104.24425562378 0.959093779557058 0.8965597969992626 0.8479570386537254 0.9626967696901138 0.8281945391046717 0.8197604252008319 0.9926382587293967 0.7577011259775489 0.7449235020584973 1.0 16.23452265600637 -1.5228787661564274 0.48260273342315446 0.8537381073665797 3.623111563503219 0.08396902173562049 0.08613278787372262 248.61013990187078 2.76753346293195 0.04953312634104441 691.6559088450625 0.02999999855793084 1.5228787661564274 2.7693734561366394 DAHDVS(ph)PTSTDTEAQLTVER ddPTM_PC-9_AZD4547_30min_R2 7 DAHDVSPTSTDTEAQLTVER 20 0 Q8IVF2-3;Q8IVF2 Q8IVF2-3 AHNAK2 Protein AHNAK2 1 DAHDVS(0.999)PT(0.001)STDTEAQLTVER;DAHDVS(0.704)PT(0.285)S(0.011)TDTEAQLTVER;DAHDVS(0.999)PT(0.001)STDTEAQLTVER;DAHDVS(0.986)PT(0.013)S(0.001)TDTEAQLTVER;DAHDVS(0.999)PTSTDTEAQLTVER;DAHDVS(0.957)PT(0.004)S(0.005)T(0.002)DT(0.016)EAQLT(0.016)VER;DAHDVS(0.981)PT(0.019)STDTEAQLTVER 164.01 5.6193e-08 230394400.0 191393.4 195705.6 277640.0 350253.0 319939.0 281927.0 212165.0 300792.0 261981.8 278498.0 True False 252252.51996997168 258963.60796840375 273958.3121932468 269507.582204907 275520.9923991333 264298.06012214074 231047.27398193342 254311.50791253507 275829.623101555 268747.8697881943 0.9386214676558257 0.9635931558173774 1.0193878463451969 1.0028268593061276 1.0252025164563239 0.9834424374430928 0.8597176013489018 0.9462828788669587 1.0263509188703224 1.0 18.035893793759605 -7.02386444137831 24.968372351193466 0.9490355119891101 0.9921674302303849 0.08088029388554963 0.04710612274399215 1518.0449572733844 1588263.120219613 0.018552800393012055 0.01446326788829546 9.465325614496193e-08 7.02386444137831 0.043131918241274825 DAHDVS(ph)PTSTDTEAQLTVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 DAHDVSPTSTDTEAQLTVER 20 0 Q8IVF2-3;Q8IVF2 Q8IVF2-3 AHNAK2 Protein AHNAK2 1 DAHDVS(0.998)PT(0.002)STDTEAQLTVER;DAHDVS(0.995)PT(0.001)S(0.001)T(0.001)DT(0.001)EAQLTVER;DAHDVS(0.995)PT(0.005)STDTEAQLTVER;DAHDVS(0.998)PT(0.002)STDTEAQLTVER;DAHDVS(0.982)PT(0.013)S(0.004)TDTEAQLTVER 175.23 1.5402000000000001e-09 138857000.0 171528.9 173541.5 198657.3 217774.0 254569.0 232452.6 205465.6 206279.6 202149.2 165247.3 True False 200565.3549197984 190769.5532241816 203394.04344400612 205572.82881283358 204688.03188885725 220262.3764465847 186002.4109258752 200864.97907130208 205105.24962128693 195205.32739309306 1.0274584080172753 0.9772763672582616 1.0419492447274408 1.0531107503990558 1.048578102977018 1.1283625267205604 0.9528551982155408 1.0289933259188768 1.050715430569464 1.0 17.574632900794157 -3.4365442735471947 13.757690734471502 1.0321950612156912 0.9781112935059404 0.0 0.045576622819124314 0.0 0.0 0.010494619401050731 0.0 0.0003659786294736758 3.4365442735471947 -0.05408376770975076 DAHDVS(ph)PTSTDTEAQLTVER ddPTM_PC-9_Lapatinib_30min_R1 5 DAHDVSPTSTDTEAQLTVER 20 0 Q8IVF2-3;Q8IVF2 Q8IVF2-3 AHNAK2 Protein AHNAK2 1 DAHDVS(0.992)PT(0.006)S(0.002)T(0.001)DTEAQLTVER;DAHDVS(1)PTSTDTEAQLTVER;DAHDVS(0.987)PT(0.012)S(0.001)TDTEAQLTVER;DAHDVS(1)PTSTDTEAQLTVER;DAHDVS(0.943)PT(0.051)S(0.003)T(0.003)DTEAQLTVER 201.85 1.7052e-16 223236000.0 407236.0 349387.9 446150.0 330514.6 468173.0 414626.0 353797.0 386245.0 441968.0 347650.8 True False 401428.73996206454 348578.9137838779 409469.2691888042 354821.7462483839 440635.984603533 396893.412520414 372114.87751798413 404191.35275669675 392188.90971063374 407741.77756442776 0.9845170695039567 0.8549011481385386 1.0042367295171353 0.8702118982456196 1.0806741149646055 0.9733940311223085 0.9126238663615622 0.9912924674313758 0.9618560846359765 1.0 18.63729625858027 -6.226869016267036 24.99947499000074 0.9818416912344688 0.928624194459046 0.1941517399571393 0.05756487692064762 1140.0171401821592 824400.9373527165 0.01642390554287618 0.021202103458399554 5.931041785339627e-07 6.226869016267036 -0.05321749677542287 DAIAQAVR ddPTM_PC-9_Lapatinib_30min_R1 2 DAIAQAVR 8 0 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 ; 110.12 0.017357 40046000.0 119813.0 115393.0 141877.0 122755.0 129471.0 132489.0 116576.0 101642.0 102543.0 100588.0 False True 118104.44464898664 115125.8145982248 130212.42072105747 131782.81219867567 121855.77032977958 126822.75431694376 122611.73486925123 106364.65838236411 90993.52751433919 117974.50177491514 1.0011014488056023 0.9758533654829465 1.103733592954613 1.1170448716969839 1.032899215478524 1.0750013978351889 1.0393070792804322 0.9015902316358023 0.7712982563634534 1.0 16.848115553193814 -7.786052990118995 4.264827317050249 0.8714999568173004 1.0525264418401485 0.5497483725024986 0.06548921408224664 0.1426609189737639 5.8427056838335725 0.03649475827135 0.01760887316640131 1.6366168186578822e-08 7.786052990118995 0.18102648502284813 DAIHFYNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DAIHFYNK 8 0 P31948-2;P31948;P31948-3 P31948-2 STIP1 Stress-induced-phosphoprotein 1 0 68.22399999999999 0.03708 7225000.0 102790.0 137350.0 137900.0 132080.0 154320.0 111690.0 118810.0 116320.0 109010.0 82739.0 False True 120190.31680495868 150985.20028547288 141188.05898866258 124679.98580913736 124082.10379538924 105832.77978099226 107555.45669008905 113266.72325122774 110604.06502334133 97738.9257384364 1.229707774020409 1.5447806403104047 1.4445427747640933 1.2756430957999185 1.2695259627413034 1.0828109576753093 1.1004362476616851 1.15887014713407 1.1316275904170865 1.0 16.57664562736764 -6.342193830259172 1.4864835324046561 1.1032857076923914 1.4146788794534086 0.6912643498499909 0.08863527211423562 0.22271143140743044 0.9880138064234776 0.03342207558581945 0.042937579435341884 4.5478503943472665e-07 6.342193830259172 0.3113931717610172 DAIHFYNK ddPTM_PC-9_Lapatinib_30min_R1 2 DAIHFYNK 8 0 P31948-2;P31948;P31948-3 P31948-2 STIP1 Stress-induced-phosphoprotein 1 0 ; 79.906 0.016828 9322400.0 200537.0 272510.0 301080.0 267020.0 331410.0 308850.0 319900.0 306480.0 317430.0 301160.0 False True 197677.3056060178 271879.01983796386 276326.36460240965 286657.5415526077 311917.11537712946 295641.20546451444 336462.8567172787 320720.17966024805 281677.69071391237 353215.10472952365 0.5596513369873869 0.769726481675116 0.7823175195579704 0.8115664865807969 0.8830797754699128 0.8370004609256539 0.9525721075120129 0.9080024477034787 0.7974678515790217 1.0 18.430187513494623 -3.9835565506465356 0.5562380063056945 0.9017831466760664 1.2356170722105885e-19 0.7575486997105729 0.05684268680930881 4.408394004864827 0.5349930460567025 0.028508700473145077 3.121494429152857 0.00010385883562485992 3.9835565506465356 -0.9017831466760664 DALDGPAAEAEPEHSFDGLR ddPTM_PC-9_AZD4547_30min_R2 1 DALDGPAAEAEPEHSFDGLR 20 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 65.92399999999999 0.0052193000000000005 2948000.0 5937.9 5747.4 6655.6 9656.3 8685.9 6877.4 8306.9 11162.0 6992.0 7147.1 False True 7826.028684007367 7605.134653467274 6567.3423953082165 7430.189223347813 7480.0127145475635 6447.355090800128 9046.198007402381 9437.169377243126 7361.582845549094 6896.882204407932 1.1347197838184913 1.1026916841651557 0.9522190173279892 1.0773258123212595 1.0845498723708724 0.9348216918478756 1.3116358579563356 1.368323990108407 1.0673783642185686 1.0 12.751728611078631 -7.265575440006232 24.98561368800174 1.2175282158270604 1.0488986355487588 0.23860633797242514 0.11668663654991172 432.3193042325406 2611591.2832537703 0.046634621626030645 0.03273279092915615 5.4253100169231e-08 7.265575440006232 -0.16862958027830155 DALDGPAAEAEPEHSFDGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DALDGPAAEAEPEHSFDGLR 20 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ;; 135.29 5.7215e-05 7460900.0 44458.4 51860.2 53751.4 46878.2 53591.2 46123.6 53892.1 39039.4 42324.8 38815.5 False True 51984.32902657431 57008.53792387828 55033.03722931965 44251.766435175 43090.38906764813 43704.79722004273 48787.05014298421 38014.65711566343 42943.72012934516 45852.44288667105 1.1337308495222127 1.2433042676653159 1.2002203975334393 0.9650907050808114 0.9397621229069602 0.9531618048805721 1.06400111033487 0.8290650338875183 0.9365634070028701 1.0 15.484710978072085 -5.771246284130233 6.583459088109301 0.9513465691527069 1.1984970966189643 0.7627516769776922 0.06054955367528489 0.06492799790940869 12.210821746389293 0.017012264011816925 0.026938683048968546 1.6933772305318818e-06 5.771246284130233 0.24715052746625743 DALDGPAAEAEPEHSFDGLR ddPTM_PC-9_Lapatinib_30min_R1 2 DALDGPAAEAEPEHSFDGLR 20 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 170.89 1.4099999999999999e-08 6585200.0 13472.7 16248.2 13454.5 15044.1 16099.8 13200.9 14511.2 16818.4 15483.2 14104.7 False True 13280.576827409412 16210.578291186424 12348.322945871922 16150.493299646412 15152.841417424648 12636.328279800895 15262.518932153092 17599.8442625878 13739.318970675871 16542.678601668613 0.8028069182260386 0.9799246350316756 0.7464524484339786 0.976292515168454 0.9159847556910297 0.7638622851879806 0.9226147288271445 1.063905349694248 0.8305377443100433 1.0 14.013905235126556 -7.519658511228492 24.987588306824886 0.9669849396165828 0.8692125827598987 0.19422504456655376 0.09251527002216076 221.85740531449832 1721558.580793729 0.04040197457559194 0.02393077985141316 3.022327263273168e-08 7.519658511228492 -0.09777235685668417 DALDGPAAEAEPEHSFDGLRR ddPTM_PC-9_AZD4547_30min_R2 2 DALDGPAAEAEPEHSFDGLRR 21 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 121.72 6.3815e-07 11160600.0 58254.0 39090.6 71835.0 109267.0 94158.0 74687.0 61576.0 71949.0 56795.0 71158.0 False True 76777.5602415273 51725.87199165321 70882.42096384482 84077.18130832163 81085.78698538661 70016.81008325657 67056.14471148181 60830.93527354111 59797.06775070945 68666.78007880966 1.1181179626219375 0.7532881537810107 1.0322665615380864 1.2244229482120068 1.180859025169427 1.0196605986606253 0.9765441838764056 0.8858859437376375 0.8708296454570851 1.0 16.067324693925137 -7.4159525625722384 2.695695127380921 0.910704257966913 1.0541322040595384 0.1989044053101645 0.12311143885270633 0.5094642468340619 7.189025919991031 0.06743013942382418 0.04047711880029725 3.837491596303337e-08 7.4159525625722384 0.14342794609262544 DALDGPAAEAEPEHSFDGLRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DALDGPAAEAEPEHSFDGLRR 21 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 94.882 0.00014482 10406500.0 58281.0 41952.0 60897.0 70616.0 79391.0 80901.0 73620.0 85242.0 81624.0 69969.0 False True 68146.82219777998 46116.71730889087 62349.01543315856 66659.614460161 63834.90346306214 76658.40914192896 66646.18063735688 83004.4878213645 82817.59658256306 82653.82582570061 0.8244847896271272 0.5579501837717863 0.7543391344599027 0.8064915785112233 0.7723163788894226 0.927463530890697 0.806329047343792 1.0042425379849127 1.001981405642466 1.0 16.334793979127802 -6.9205580274912215 0.5668855491502948 1.0193611067980584 0.6822491046883622 0.6535828941251225 0.07899211100710907 0.5163073532400662 0.35547265890857777 0.06691225175333619 0.06869563972312334 1.2007206301270153e-07 6.9205580274912215 -0.33711200210969616 DALDGPAAEAEPEHSFDGLRR ddPTM_PC-9_Lapatinib_30min_R1 2 DALDGPAAEAEPEHSFDGLRR 21 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 131.82 5.5335e-07 10489600.0 59765.0 43866.0 50118.0 36962.0 39024.0 38311.0 27249.0 28679.0 45655.0 29301.0 False True 58912.74014044128 43764.43097211902 45997.49150107463 39680.30878161742 36728.68504413596 36672.52783730291 28659.819889619022 30011.53103783686 40512.85313153658 34365.638808871656 1.714292013254608 1.2734938877615458 1.3384733441707524 1.1546506963628378 1.0687618888275772 1.0671277796190919 0.8339673255897793 0.8733005431602581 1.1788767657383978 1.0 15.06867915683333 -1.5228787452904784 0.4182705254976002 0.9561443832559603 14.34091314129863 0.7975036455644817 0.10860293303832562 33.318973886362414 0.4283075263846603 0.07529109392297609 372.66963548168917 0.029999999999299497 1.5228787452904784 13.38476875804267 DALGDSLQVPVS(ph)PSSTTSSR ddPTM_PC-9_AZD4547_30min_R2 2 DALGDSLQVPVSPSSTTSSR 20 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 DALGDSLQVPVS(0.983)PS(0.014)S(0.002)T(0.001)TSSR;DALGDSLQVPVS(0.943)PS(0.008)S(0.002)T(0.002)T(0.012)S(0.017)S(0.017)R 222.93 1.0645999999999999e-35 56401000.0 36670.8 28615.1 49535.7 59085.0 49246.4 47959.9 41485.8 43105.8 44872.3 44895.3 True False 48331.351599975955 37864.37147622077 48878.82425194857 45463.8661041502 42409.387414740595 44960.95987135623 45177.955831356325 36444.78908274207 47244.15816938391 43323.52921206579 1.1155912844356979 0.8739909274444654 1.1282281277845574 1.0494035673226805 0.9788996461287691 1.0377954125407312 1.0428041448380911 0.8412239202477539 1.0904965276057474 1.0 15.402863151797524 DALGDSLQVPVS(ph)PSSTTSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DALGDSLQVPVSPSSTTSSR 20 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 DALGDSLQVPVS(0.968)PS(0.025)S(0.004)T(0.001)T(0.001)SSR;DALGDSLQVPVS(0.776)PS(0.208)S(0.013)T(0.001)T(0.001)SSR;DALGDSLQVPVS(0.979)PS(0.02)STTSSR;DALGDSLQVPVS(0.878)PS(0.065)S(0.042)T(0.013)T(0.002)SSR;DALGDSLQVPVS(0.63)PS(0.265)S(0.081)T(0.011)T(0.011)S(0.001)S(0.001)R;DALGDSLQVPVS(0.935)PS(0.054)S(0.006)T(0.002)T(0.002)S(0.001)SR 264.1 5.7906e-79 484261000.0 97428.0 112842.0 138188.0 149873.0 184012.0 181478.0 203327.0 203199.0 186826.0 138252.0 True False 113920.63610928606 124044.2080132022 141482.9260009083 141476.10170482157 147956.1695411947 171960.97420623977 184066.39459999834 197865.24155713705 189557.97680993308 163315.99319776983 0.6975473367836807 0.7595349701176485 0.8663139673625078 0.8662721815217391 0.9059502786235091 1.0529340748520641 1.1270567627574632 1.2115484692153162 1.1606822644759913 1.0 17.31730655239896 -6.468287986141348 0.8830905469500218 1.1529791456444165 0.746450144186928 0.8503228783474452 0.0636906718969194 0.20927907558353787 0.3573977672034196 0.03553982220047815 0.04566570445737498 3.4018253556792675e-07 6.468287986141348 -0.4065290014574885 DALGDSLQVPVS(ph)PSSTTSSR ddPTM_PC-9_Lapatinib_30min_R1 4 DALGDSLQVPVSPSSTTSSR 20 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 DALGDSLQVPVS(0.998)PS(0.001)STTSSR;DALGDSLQVPVS(0.969)PS(0.013)S(0.013)T(0.003)T(0.001)S(0.001)SR;DALGDSLQVPVS(0.93)PS(0.031)S(0.031)T(0.003)T(0.003)S(0.001)S(0.001)R;DALGDSLQVPVS(0.962)PS(0.028)S(0.007)T(0.002)T(0.002)SSR 298.42 3.886099999999999e-122 559022000.0 146127.0 148898.0 164143.0 144216.0 177888.0 182498.0 180574.0 175921.0 200758.0 152540.0 True False 144043.20218359045 148553.23582926567 150647.79615030336 154822.1257304727 167424.9775812642 174692.98596361652 189923.23816463203 184094.93189118474 178146.51996453883 178906.33575322607 0.8051319232331493 0.8303408328376483 0.842048413299901 0.8653808993328562 0.9358247536420473 0.9764494098441476 1.0615791630018183 1.0290017461713348 0.9957529967539256 1.0 17.448844954045228 -6.432747782127799 1.2667746338171497 1.0245715645478233 0.8218174976387128 0.9457506360340707 0.020277266414189997 0.09400780725070385 0.3114855669032265 0.008957707993801486 0.010947202854327334 3.6919194569439803e-07 6.432747782127799 -0.20275406690911046 DALGDSLQVPVSPS(ph)STTSSR ddPTM_PC-9_AZD4547_30min_R2 3 DALGDSLQVPVSPSSTTSSR 20 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 DALGDSLQVPVS(0.027)PS(0.951)S(0.011)T(0.003)T(0.003)S(0.003)S(0.003)R;DALGDSLQVPVS(0.183)PS(0.599)S(0.082)T(0.025)T(0.082)S(0.025)S(0.004)R;DALGDSLQVPVS(0.276)PS(0.482)S(0.165)T(0.033)T(0.02)S(0.02)S(0.004)R 267.93 3.1304999999999994e-79 577547600.0 50553.1 46819.9 57003.1 88291.8 70693.0 67350.3 60867.0 66392.3 60270.4 67132.1 True False 66627.93423019799 61953.51706195367 56247.20164883611 67937.48960471198 60878.4972000036 63138.87509406401 66284.04508499683 56132.895578277996 63456.170299539706 64781.82561242093 1.0284973231353811 0.9563410181215243 0.8682558899366919 1.048712180653427 0.9397465512044951 0.9746387122804099 1.0231889030352963 0.8664914124852228 0.979536616939257 1.0 15.983301504750694 -9.940797294563112 13.200027175934608 0.9999999999909553 0.9627529580123952 0.029555650462793848 0.05878193945791314 0.0 0.0 0.05491972678816293 0.01331999026339174 1.1460477304171542e-10 9.940797294563112 -0.0372470419785601 DALGDSLQVPVSPS(ph)STTSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DALGDSLQVPVSPSSTTSSR 20 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 DALGDSLQVPVS(0.031)PS(0.698)S(0.188)T(0.04)T(0.031)S(0.01)S(0.002)R;DALGDSLQVPVS(0.206)PS(0.699)S(0.061)T(0.018)T(0.01)S(0.003)S(0.002)R;DALGDSLQVPVS(0.234)PS(0.744)S(0.012)T(0.004)T(0.004)SS(0.002)R 173.19 1.3559999999999998e-28 0.0 23723.7 26490.100000000002 27436.0 31232.5 35757.1 38913.0 31645.0 35484.0 35718.2 29718.6 True False 27739.653845566696 29119.862061028063 28090.1782916094 29482.644282131183 28750.75293949009 36872.33377757855 28647.356510040143 34552.58259840577 36240.511102804434 35106.34692769185 0.7901606482355386 0.8294757105034574 0.800145294224615 0.8398095177164476 0.8189616823051311 1.0503039195027635 0.8160164476538896 0.984226090785616 1.0323065278608627 1.0 15.09944426060154 -6.902898138583613 0.5648783017390778 1.0130673616082029 0.7879075755619858 0.5765552974209001 0.0654923051580812 0.6561819106901884 0.44928852284592 0.056263615546590276 0.05885555198540657 1.250552306087298e-07 6.902898138583613 -0.22515978604621711 DALNIETAIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DALNIETAIK 10 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ; 146.11 0.00064945 8046300.0 38996.0 34324.0 58500.0 43352.0 56032.0 50922.0 51961.0 45804.0 55617.0 38317.0 False True 45597.25259389211 37731.45988058662 59894.861862485464 40923.127989080356 45052.93182907753 48251.56067694226 47038.87791493745 44601.693533349615 56430.293407973375 45263.5687827949 1.00737201727726 0.8335944534477072 1.323246563917692 0.9041074110938334 0.9953464351269308 1.0660131751538584 1.039221589898527 0.9853773074628426 1.2467044673115357 1.0 15.46606271718702 -8.216831599348644 24.985994495681865 1.1233531403538384 1.0208122099753372 0.08999120065634947 0.13230095299435193 944.0846539437639 528807.9169560377 0.08520632193249095 0.03220455319778313 6.069716413629113e-09 8.216831599348644 -0.1025409303785012 DALNIETAIK ddPTM_PC-9_Lapatinib_30min_R1 4 DALNIETAIK 10 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ;;; 198.25 0.0031595 67094100.0 204473.0 203200.0 256992.0 225081.0 229173.0 190413.0 246537.0 220602.0 254427.0 233440.0 False True 201557.17752424462 202729.50288457057 235863.10977780778 241634.20758820494 215693.49471145353 182269.4798643828 259301.4795451945 230851.97426719475 225770.75202491408 273789.79296075186 0.7361749148666696 0.74045675951708 0.8614751749040516 0.8825537467090439 0.7878069243522657 0.6657278121778315 0.9470823464275957 0.8431723176045781 0.8246134729254813 1.0 18.062709137543244 -14.522878745274587 0.13380301162895364 1.6476795452540127 0.736773584318199 0.4130126791814771 0.07354178173913324 154.19352119022892 1.2827680414521954 26.58917875079011 0.5417724641448073 3.0000000000397214e-15 14.522878745274587 -0.9109059609358138 DAMEQCHNYNAR ddPTM_PC-9_AZD4547_30min_R2 2 DAMEQCHNYNAR 12 0 J3KMZ8;Q92785-2;Q92785;E9PN04 J3KMZ8 DPF2 Zinc finger protein ubi-d4 0 ; 98.182 0.0030221000000000002 1763900.0 6106.1 5200.200000000001 7610.2 8365.9 8107.700000000001 7107.7 3510.5 6877.5 4969.1 5986.2 False True 8047.712785230028 6881.062954546491 7509.2837755836545 6437.271006866551 6982.085804089078 6663.25439539362 3822.9276992603823 5814.740404227707 5231.756481381293 5776.624960057472 1.3931513367885253 1.1911908773939222 1.2999431030241133 1.1143654039126865 1.2086790907089826 1.1534857189910641 0.6617926082607148 1.0065982203161508 0.905677020328708 1.0 12.496011117261379 -7.071118065111124 7.245390424300733 0.8941069572028407 1.2298567008072505 0.6855035059329881 0.11176615795449131 0.15865683771428024 14.117991931342061 0.04152606822591484 0.03224435805431099 8.48949652484649e-08 7.071118065111124 0.3357497436044098 DAMEQCHNYNAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DAMEQCHNYNAR 12 0 J3KMZ8;Q92785-2;Q92785;E9PN04 J3KMZ8 DPF2 Zinc finger protein ubi-d4 0 81.676 0.012281 0.0 4501.4 6161.6 7727.8 4810.1 7651.2 5824.0 6591.9 4522.5 5957.2 6265.2 False True 5263.398113297414 6773.282927404219 7912.060059844703 4540.605691554608 6152.00228459877 5518.579187433956 5967.467510776862 4403.78916698484 6044.312780084849 7401.031164704093 0.7111709160743488 0.9151809763626401 1.0690483371530353 0.6135098732199636 0.8312358302094434 0.7456500404635978 0.8063021730317835 0.5950237296644206 0.8166852220418277 1.0 12.85351057602052 -5.767368586873516 24.99934205053966 0.7584763739873093 0.9001381614862808 0.1491409921648501 0.1347833071551077 228.84993800222753 964905.4322950692 0.03632364949182156 0.055505559478463855 1.708564636261744e-06 5.767368586873516 0.14166178749897151 DAMEQCHNYNAR ddPTM_PC-9_Lapatinib_30min_R1 1 DAMEQCHNYNAR 12 0 J3KMZ8;Q92785-2;Q92785;E9PN04 J3KMZ8 DPF2 Zinc finger protein ubi-d4 0 113.38 0.00057059 1957300.0 5027.7 4659.2 5406.7 2949.4 6086.4 5653.1 4613.8 3204.0 7233.7 6255.0 False True 4956.004076032742 4648.411908660397 4962.18199646555 3166.3087149099756 5728.409918322796 5411.330091019741 4852.679988503222 3352.86953677706 6418.964531762043 7336.1684157364025 0.6755575656362927 0.6336293886996037 0.6763996837669991 0.4316025117577869 0.7808449307182079 0.7376234819544493 0.6614733623200377 0.45703279242949335 0.8749750779975394 1.0 12.840811043791176 -8.474830344158418 5.991883674443598 0.999512754110064 0.6367914276566837 0.5897023347861234 0.10450496457042223 0.12210813489258183 10.245716159247195 0.10096605008343239 0.026173613097347222 3.350963179677231e-09 8.474830344158418 -0.3627213264533803 DANDPVDDR ddPTM_PC-9_Lapatinib_30min_R1 1 DANDPVDDR 9 0 O94906-2;O94906 O94906-2 PRPF6 Pre-mRNA-processing factor 6 0 112.11 0.0023166999999999997 0.0 42061.0 42200.0 43329.0 34238.0 36822.0 45991.0 36833.0 37692.0 47163.0 32636.0 False True 41461.20242695727 42102.28849276025 39766.65687477681 36755.97673461984 34656.20235483738 44024.072140257354 38740.03251474686 39443.307921411026 41851.006291592596 38277.08911526347 1.0831858792110733 1.0999344376992197 1.0389153876102704 0.9602605000588441 0.9054032883868848 1.1501415901216532 1.0120945299181276 1.0304678028842718 1.0933696176730423 1.0 15.224193499899725 -5.358883295857264 4.738872423645788 1.021625351651457 1.0912424397082343 0.15877923664084292 0.0630879615963319 0.4020353758644328 14.648325244534888 0.017371277952955528 0.03802554556540776 4.3763969243023505e-06 5.358883295857264 0.06961708805677724 DANGNSFATR ddPTM_PC-9_AZD4547_30min_R2 1 DANGNSFATR 10 0 P62701;C9JEH7;Q8TD47;P22090 P62701 RPS4X;RPS4Y1;RPS4Y2 40S ribosomal protein S4, X isoform;40S ribosomal protein S4, Y isoform 2;40S ribosomal protein S4, Y isoform 1 0 105.4 0.011363 5801200.0 14211.0 13018.0 17235.0 25311.0 17967.0 18799.0 13463.0 27690.0 17058.0 20545.0 False True 18729.802392837315 17225.81391913507 17006.452638851042 19475.940001051807 15472.592182994982 17623.49555819811 14661.180918713153 23411.14675289934 17959.651055402795 19825.72580341132 0.9447221543644353 0.8688617047337105 0.8577972280805388 0.9823569736700724 0.7804300501489174 0.8889205738518646 0.7395028592693678 1.1808468948395876 0.9058760941963881 1.0 14.275086062316785 -7.757218129805682 24.999999916588624 1.0325211091935524 0.8679285191773515 0.40183411688601123 0.09098443123894884 98.99700543271652 586312.2918724611 0.04194276197507041 0.023102135987314944 1.7489680270369542e-08 7.757218129805682 -0.16459259001620097 DANGNSFATR ddPTM_PC-9_Lapatinib_30min_R1 2 DANGNSFATR 10 0 P62701;C9JEH7;Q8TD47;P22090 P62701 RPS4X;RPS4Y1;RPS4Y2 40S ribosomal protein S4, X isoform;40S ribosomal protein S4, Y isoform 2;40S ribosomal protein S4, Y isoform 1 0 ; 141.91 0.00057991 23718000.0 52697.0 53125.0 47348.0 40901.0 56246.0 44501.0 45060.0 43695.0 52638.0 33859.0 False True 51945.53111655378 53001.992326490275 43455.230208565445 43908.99598173622 52937.720863890674 42597.79596689768 47392.98631972669 45725.22921643995 46709.35413728665 39711.48303571842 1.308073311435674 1.3346767301240736 1.0942736681347236 1.1057002313976125 1.3330582697270696 1.072682073560012 1.1934327981933879 1.1514359505363343 1.176217823325158 1.0 15.27726861924146 -1.5228787481761454 0.02225862236199753 9.432910990644439e-09 2.7322142534640275 0.39193368751432367 0.08593901571307704 2815.715991148592 4.8435517403274435 213.21158614372874 411.1797671679057 0.02999999979996468 1.5228787481761454 2.7322142440311166 DANSSFFDNSS(ph)SPHLLDQLK ddPTM_PC-9_AZD4547_30min_R2 1 DANSSFFDNSSSPHLLDQLK 20 0 P49454 P49454 CENPF Centromere protein F 1 DANS(0.001)S(0.001)FFDNS(0.12)S(0.489)S(0.39)PHLLDQLK 58.418 0.0097667 2152400.0 13588.0 13577.0 20315.0 28079.0 24688.0 18585.0 15180.0 21180.0 13871.0 19297.0 True False 17908.70135204231 17965.49973729428 20045.609826414802 21605.8203662255 21260.497345899705 17422.877012027864 16530.990592443402 17907.117667981496 14604.19274179226 18621.41790354967 0.9617259783761417 0.9647761427377474 1.0764813898835086 1.160267197596534 1.1417227976956021 0.935636432320584 0.8877407014904174 0.9616409320027122 0.7842685673795208 1.0 14.184675308758601 -6.898899371277806 6.55466877659105 0.9061944462544946 1.0615435512280451 0.46473078897248754 0.07930622134457237 0.20760567081610393 11.650750425896534 0.030008174495354478 0.026455037549539664 1.2621199417232424e-07 6.898899371277806 0.15534910497355048 DANSSFFDNSS(ph)SPHLLDQLK ddPTM_PC-9_Lapatinib_30min_R1 1 DANSSFFDNSSSPHLLDQLK 20 0 P49454 P49454 CENPF Centromere protein F 1 DANSSFFDNS(0.03)S(0.485)S(0.485)PHLLDQLK 80.453 0.00081 1863100.0 10276.0 4494.2 6498.1 6616.8 5814.7 5521.6 5382.6 3637.3 6728.1 5148.4 True False 10129.462355612395 4483.793956022822 5963.851301391384 7103.421544997732 5472.690778140047 5285.454039478268 5661.284690735931 3806.3022366164787 5970.310527966077 6038.294080188214 1.677537102548119 0.7425597190991834 0.9876715546132345 1.17639542736155 0.9063306134916607 0.8753223955785737 0.9375635925568349 0.6303605266767391 0.988741265112411 1.0 12.559925306120702 -4.753501846301062 24.999323591925815 0.914014974779902 1.6775384880451423 0.723688365433696 0.14114314364675176 159.20505552659802 501377.71734765085 0.03615273858420204 0.38698920227989275 1.7639982652358543e-05 4.753501846301062 0.7635235132652403 DANSSFFDNSSS(ph)PHLLDQLK ddPTM_PC-9_AZD4547_30min_R2 1 DANSSFFDNSSSPHLLDQLK 20 0 P49454 P49454 CENPF Centromere protein F 1 DANS(0.006)S(0.005)FFDNS(0.1)S(0.201)S(0.689)PHLLDQLK 51.46 0.02424 4313100.0 20568.0 15465.0 24104.0 42651.0 34115.0 22892.0 14191.0 21106.0 16039.0 23454.0 True False 27108.19615902314 20463.758815442005 23784.36521072617 32818.4709013812 29378.721117764442 21460.559621164484 15453.971508390285 17844.55266763066 16886.788795732522 22632.882598841992 1.1977350229532904 0.9041605162786038 1.0508765335946688 1.4500349550286782 1.298054765647377 0.9482026660741177 0.6828105717820047 0.7884348177789636 0.7461174564037429 1.0 14.466132722272212 -6.9703276273998185 5.141812301131488 0.7890265335812979 1.1710246862697589 0.5695711461281541 0.15446362240790687 0.14657132957035143 10.154886698919507 0.06127274543598666 0.052529932599646154 1.0707112666508414e-07 6.9703276273998185 0.38199815268846093 DANSSFFDNSSS(ph)PHLLDQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DANSSFFDNSSSPHLLDQLK 20 0 P49454 P49454 CENPF Centromere protein F 1 DANSSFFDNS(0.032)S(0.157)S(0.81)PHLLDQLK;DANS(0.001)S(0.001)FFDNS(0.063)S(0.367)S(0.568)PHLLDQLK 117.4 9.2658e-06 5405100.0 22563.0 24166.0 27194.0 28415.0 32867.0 24683.0 31772.0 24350.0 21884.0 18002.5 True False 26382.470260436647 26565.04077246988 27842.408093819293 26822.999672672966 26426.947287733656 23388.580028061875 28762.32615063977 23710.838300957617 22204.01209953951 21266.210742288407 1.2405816240678187 1.2491666284320513 1.3092322102523863 1.2612966173298914 1.2426730651729596 1.0998000683569398 1.352489472581269 1.1149536035495033 1.0440981879007838 1.0 14.376275373340837 -7.966131290538811 5.367644188814548 1.0380239925377568 1.2472809807394036 0.6926533905534971 0.06214863281677558 0.1017879025935799 7.620657854411334 0.036617003059558215 0.01645258440736605 1.0811070749660863e-08 7.966131290538811 0.20925698820164684 DAPAGS(ph)PPASPGPQGPSTK ddPTM_PC-9_AZD4547_30min_R2 1 DAPAGSPPASPGPQGPSTK 19 0 A0A0A0MRX4;Q3MIN7;Q3MIN7-2 A0A0A0MRX4 RGL3 Ral guanine nucleotide dissociation stimulator-like 3 1 DAPAGS(0.999)PPAS(0.001)PGPQGPSTK 184.97 1.2855e-38 0.0 13675.0 11532.0 18100.0 22042.0 19867.0 16704.0 15732.0 20071.0 16366.0 17314.0 True False 18023.365542329895 15259.493479448889 17859.9821736701 16960.55744550526 17108.809979382284 15659.496239381948 17132.11752307772 16969.48813569673 17231.07334814881 16707.842129971443 1.0787368830831 0.91331324301153 1.0689580398675116 1.0151255508382189 1.0239987813083034 0.9372542616554346 1.0253937875283838 1.0156600717010567 1.0313165047950008 1.0 14.028237796406549 DAPAGS(ph)PPASPGPQGPSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DAPAGSPPASPGPQGPSTK 19 0 A0A0A0MRX4;Q3MIN7;Q3MIN7-2 A0A0A0MRX4 RGL3 Ral guanine nucleotide dissociation stimulator-like 3 1 DAPAGS(1)PPASPGPQGPSTK;DAPAGS(0.999)PPAS(0.001)PGPQGPSTK 237.39 1.1148e-43 13416700.0 47236.0 51041.0 49225.0 44935.0 35932.0 19783.2 21921.3 14188.0 12982.3 10629.7 True False 55232.1218464737 56108.01316178242 50398.71068685207 42417.43763123559 28891.38254002025 18745.734165666803 19844.755767531784 13815.580033428607 13172.141577401373 12556.780465341091 4.398589431337436 4.468343881351621 4.013665033482215 3.3780504284768798 2.3008590951928736 1.4928774312339301 1.5804015864024046 1.100248592508408 1.0490062810095937 1.0 13.616178986924268 -6.26192380641054 0.9743464020573884 1.100627669590806 4.562271032999283 0.991898156505408 0.12325397894581709 0.04439913819252104 0.08924852599337219 0.05872195847842575 0.09240729790533435 5.471119410097285e-07 6.26192380641054 3.461643363408477 up DAPAGS(ph)PPASPGPQGPSTK ddPTM_PC-9_Lapatinib_30min_R1 2 DAPAGSPPASPGPQGPSTK 19 0 A0A0A0MRX4;Q3MIN7;Q3MIN7-2 A0A0A0MRX4 RGL3 Ral guanine nucleotide dissociation stimulator-like 3 1 DAPAGS(0.999)PPAS(0.001)PGPQGPSTK;DAPAGS(1)PPASPGPQGPSTK 133.93 4.007e-05 16702800.0 62577.0 60173.0 70880.0 50983.0 37657.0 27194.0 18366.0 20979.0 18587.2 13160.5 True False 61684.64050478365 60033.67311551809 65052.52000471227 54732.4598943023 35442.089296510545 26030.97601231018 19316.901614471833 21953.76092760485 16493.71380410681 15435.274889736029 3.9963422061114047 3.8893815331684563 4.214535890641646 3.5459336024328056 2.29617480412211 1.6864601504194758 1.25147765442888 1.4223109782258176 1.0685727285022057 1.0 13.913943555960701 -6.4259241083470675 1.4483075319255752 1.2217082414811162 4.068159004960012 0.9847853668338257 0.1554673638050219 0.04456679577137752 0.1896712912010263 0.06270084125072349 0.07540728000602018 3.7503853337399604e-07 6.4259241083470675 2.846450763478895 up DAPQDFHPDR ddPTM_PC-9_AZD4547_30min_R2 3 DAPQDFHPDR 10 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ;; 111.63 0.0013158 102196000.0 394357.0 359288.0 446310.0 646490.0 524750.0 483100.0 433325.0 505060.0 436411.0 467910.0 False True 519754.32286483236 475420.8197402211 440391.63778622623 497451.7186709328 451897.5203443312 452891.68063011364 471890.08553824376 427014.5821242079 459478.7945092854 451528.6133207195 1.151099415477469 1.0529140473375294 0.9753349506411397 1.101705858710651 1.0008170180421094 1.0030187839024631 1.0450945335839914 0.9457087979071233 1.017607258884652 1.0 18.784457888472765 DAPQDFHPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DAPQDFHPDR 10 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ;;; 117.25 0.00081623 83010100.0 485744.0 481183.0 534132.0 581824.0 607875.0 548553.0 540104.0 506963.0 488935.0 375596.0 False True 567970.8653186864 528951.6682123384 546867.7325868912 549226.2875788594 488766.2574171995 519785.9150076334 488941.4391056636 493655.75842169946 496084.74940085603 443688.5815837004 1.2801115216699364 1.1921687646869348 1.232548583141138 1.2378643723903218 1.1015975567200738 1.171510686960461 1.1019923870036004 1.1126176758023532 1.1180922160091047 1.0 18.759187900021047 -1.5228787771448702 0.08405944861932822 0.869614721346921 1.9496813723134279 0.818756298077314 0.03379967465829196 71.22188517459182 0.4357550456760864 0.7975929254109666 8.900054125325001 0.029999997798876146 1.5228787771448702 1.080066650966507 DAPQDFHPDR ddPTM_PC-9_Lapatinib_30min_R1 5 DAPQDFHPDR 10 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ;;;; 131.12 0.00015988 137576000.0 541686.0 507215.0 556035.0 442966.0 507291.0 477901.0 458981.0 445166.0 519029.0 425694.0 False True 533961.4583069532 506040.574830696 510319.94865717104 475543.19733125664 477453.1407524797 457462.2882716423 482744.79036871874 465850.03751838184 460570.4884023289 499274.64069840056 1.0694744230550777 1.013551527717953 1.02212270974412 0.9524681579381887 0.9562935944124936 0.9162538029805202 0.966892269339858 0.9330536733584879 0.9224792345913442 1.0 18.92947410518297 -5.519863588868482 1.2362666061052427 0.9434828943536054 1.058286526795779 0.6983991663123715 0.025845944318048146 0.2963342901246768 0.8042007290752037 0.008139187682805044 0.03109388611192001 3.0209004309024427e-06 5.519863588868482 0.11480363244217362 DAPSLEEVEGHVADGS(ph)ATEMGTTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DAPSLEEVEGHVADGSATEMGTTK 24 0 C9J470;E9PHA2;Q15003;Q15003-2 C9J470 NCAPH Condensin complex subunit 2 1 DAPSLEEVEGHVADGS(0.419)AT(0.419)EMGT(0.127)T(0.036)K 77.065 0.00015735 4487800.0 9409.4 11756.0 8104.1 7768.8 12122.0 8345.2 9246.4 9519.3 8496.3 6500.9 True False 11002.225575878769 12923.057987302647 8297.332478970402 7333.539322789428 9746.7811185051 7907.563021115015 8370.514053861123 9269.428461532063 8620.542314079581 7679.461708903913 1.432681871845561 1.682807790071936 1.0804575624552046 0.9549548654284705 1.2692010830920928 1.0297027735611508 1.089987081276279 1.2070414324463226 1.122545126318494 1.0 12.906789473588761 -5.269591201705775 24.92714569121986 1.100448449619719 1.5577448364258555 0.7601206791876808 0.10410648256157565 228.22044209936917 697867.9163500416 0.0262050389889581 0.05607151086650585 5.375375385532796e-06 5.269591201705775 0.4572963868061364 DAPSLEEVEGHVADGSAT(ph)EMGTTK ddPTM_PC-9_AZD4547_30min_R2 1 DAPSLEEVEGHVADGSATEMGTTK 24 0 C9J470;E9PHA2;Q15003;Q15003-2 C9J470 NCAPH Condensin complex subunit 2 1 DAPSLEEVEGHVADGS(0.372)AT(0.512)EMGT(0.086)T(0.031)K 74.3 0.00030827 4893900.0 6806.2 8326.4 8548.2 7351.1 11881.0 9470.6 7988.3 10430.0 6748.8 10685.0 True False 8970.430022245397 11017.745968373503 8434.845282705339 5656.417468362842 10231.528230988108 8878.401884859357 8699.243224612359 8818.283157556516 7105.5277900517285 10310.921402260878 0.8699930561276947 1.0685510575182582 0.818049614931196 0.5485850631275841 0.9923000895676151 0.8610677492811252 0.8436921284944403 0.8552371619885425 0.6891263654180991 1.0 13.331885639808938 -5.29151169931192 22.63897349348731 0.818751963825617 0.9692720135987869 0.1553816351520627 0.1327477690016595 324.124449561218 244006.16902104035 0.03419142511947091 0.07120260874242894 5.110793110595261e-06 5.29151169931192 0.1505200497731699 DAPSLEEVEGHVADGSAT(ph)EMGTTK ddPTM_PC-9_Lapatinib_30min_R1 1 DAPSLEEVEGHVADGSATEMGTTK 24 0 C9J470;E9PHA2;Q15003;Q15003-2 C9J470 NCAPH Condensin complex subunit 2 1 DAPSLEEVEGHVADGS(0.089)AT(0.429)EMGT(0.34)T(0.142)K 60.382 0.0041727 4278700.0 30487.0 27715.0 34174.0 25805.0 31218.0 27902.0 28432.0 24810.0 35799.0 21454.0 True False 30052.24978936893 27650.82762030452 31364.34563545485 27702.785782956485 29381.818616949455 26708.696502738818 29904.06984115556 25962.763173357936 31766.93963981774 25162.29531434193 1.1943365823323693 1.0988992567996843 1.2464818985562853 1.1009641782229038 1.1676923050896113 1.061457079693182 1.1884476144793885 1.0318121955495754 1.2624817904315477 1.0 14.618975910970882 -11.481454013095552 2.806851915252055 0.8885792340917936 1.1456903890974 0.2763501142687189 0.07261626194946649 55352502.12027569 38525070.11008562 40275186.50160981 0.01648100415595413 3.300243519303242e-12 11.481454013095552 0.25711115500560633 DAPSLEEVEGHVADGSATEMGT(ph)TK ddPTM_PC-9_AZD4547_30min_R2 1 DAPSLEEVEGHVADGSATEMGTTK 24 0 C9J470;E9PHA2;Q15003;Q15003-2 C9J470 NCAPH Condensin complex subunit 2 1 DAPSLEEVEGHVADGS(0.013)AT(0.036)EMGT(0.683)T(0.268)K 77.83800000000001 0.00020392 4105300.0 22308.0 22617.0 28477.0 38141.0 35215.0 31881.0 27827.0 33971.0 30944.0 33098.0 True False 29401.479964774804 29927.502950459202 28099.37637345875 29348.181722575813 30326.005105146563 29887.476030156577 30303.549091958033 28721.56252592065 32579.63666657195 31939.249094247134 0.9205438699581253 0.9370133550149654 0.8797757358209145 0.9188751318471661 0.9494902342775758 0.9357601345593275 0.948787149082233 0.8992560357686665 1.0200501762090632 1.0 14.963042774304215 -8.267743654297139 24.990532245636306 1.0100251019711153 0.9246068889603405 0.7310598291000721 0.0209405031916492 282.2604612041627 1118880.4310935193 0.019151447365091646 0.005416725377278386 5.398291668674412e-09 8.267743654297139 -0.08541821301077479 DAPT(ph)SPASVASSSSTPSSK ddPTM_PC-9_AZD4547_30min_R2 1 DAPTSPASVASSSSTPSSK 19 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 DAPT(0.5)S(0.5)PASVASSSSTPSSK 243.61 3.4342e-53 15393000.0 23369.0 23146.0 32551.0 43126.0 34380.0 32531.0 29053.0 33202.0 24301.0 34020.0 True False 30799.85589460384 30627.49185530041 32119.352471554448 33183.966990058085 29606.930441997418 30496.83142740267 31638.660716881324 28071.393806058633 25585.501248525234 32828.9701548821 0.9381913520069253 0.932940988121301 0.9783844062125682 1.010813523345422 0.9018537682515293 0.9289609538015735 0.9637421024057387 0.8550799392616355 0.7793574129135553 1.0 15.002681872812513 -7.763512844510171 24.99564804266539 0.8629139844691706 0.9506775012485857 0.23501359070427696 0.05806565522704218 64.84667638753886 781685.586526113 0.028880884314184407 0.014953692389460949 1.7238011078595253e-08 7.763512844510171 0.08776351677941518 DAPT(ph)SPASVASSSSTPSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DAPTSPASVASSSSTPSSK 19 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 DAPT(0.919)S(0.081)PASVASSSSTPSSK;DAPT(0.5)S(0.5)PASVASSSSTPSSK 292.19 1.8822999999999995e-107 34958000.0 76675.0 72401.0 71113.0 87274.0 91388.0 85011.0 84225.0 81127.0 79824.0 69843.0 True False 89654.56309971983 79588.49279846024 72808.60361755422 82384.32072612559 73481.17743424719 80552.87350668747 76246.59826380557 78997.50221116167 80991.27498782851 82504.9830231163 1.0866563426187283 0.964650738442805 0.8824752269466519 0.9985375150376443 0.8906271444678582 0.9763394955686264 0.9241453724369926 0.9574876488251394 0.9816531319706631 1.0 16.332193635461103 -4.773300939406536 4.655462899715118 0.9478266633458884 1.0958636436424436 0.5103246738617703 0.039341313488119076 0.13276427573779365 6.666055475473247 0.009063699896261039 0.0640954919765834 1.6853847525284538e-05 4.773300939406536 0.1480369802965552 DAPT(ph)SPASVASSSSTPSSK ddPTM_PC-9_Lapatinib_30min_R1 1 DAPTSPASVASSSSTPSSK 19 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 DAPT(0.5)S(0.5)PASVASSSSTPSSK 282.67 1.8718999999999995e-105 105100000.0 63197.0 50614.0 64995.0 48571.0 56295.0 53921.0 48108.0 47956.0 51497.0 40044.0 True False 62295.79919108959 50496.80639271488 59651.361987955366 52143.073368106176 52983.83878022838 51614.92452599019 50598.79684574817 50184.21083198522 45696.86557254932 46965.552044723954 1.326414712037603 1.0751881792984828 1.2701088221245878 1.110240827542106 1.1281425741525062 1.09899537594786 1.0773597805805493 1.0685323316160795 0.9729868719318683 1.0 15.519315346641468 -4.537833478418035 0.2180911189857536 0.96714369212456 1.5176963747920842 0.6293510098297346 0.06318482181758518 9.191541582869297 0.3601971166652811 0.10964908256826283 1.4018329273072305 2.8984547294875078e-05 4.537833478418035 0.5505526826675242 DAPTS(ph)PASVASSSS(ph)TPSSK ddPTM_PC-9_Lapatinib_30min_R1 1 DAPTSPASVASSSSTPSSK 19 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 2 DAPT(0.112)S(0.888)PASVAS(0.003)S(0.006)S(0.004)S(0.677)T(0.309)PSSK 174.68 1.5711e-28 0.0 27669.0 21095.0 25831.0 25563.0 26946.0 21315.0 16892.0 17955.0 27848.0 17651.0 True False 27274.434986126842 21046.155823572928 23707.274890543507 27442.988295668158 25361.089257874293 20403.40713769185 17766.585106809223 18789.254847950095 24711.46498755955 20701.9518315209 1.317481327755707 1.016626644427215 1.145171000468018 1.325623232002855 1.2250578817046307 0.985578910807121 0.8582082139596967 0.9076078913168698 1.1936780255634518 1.0 14.337479174564232 -6.767577418732672 23.517290159336156 0.9750645893278359 1.1987389717396575 0.46562723518503557 0.1156098863871633 65.49598322796622 250938.3117435688 0.041429999918097864 0.03751925848919991 1.7077432651109778e-07 6.767577418732672 0.22367438241182158 DAPTS(ph)PASVASSSST(ph)PSSK ddPTM_PC-9_AZD4547_30min_R2 1 DAPTSPASVASSSSTPSSK 19 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 2 DAPT(0.088)S(0.912)PASVASSS(0.003)S(0.055)T(0.755)PS(0.172)S(0.015)K 205.0 6.912599999999999e-71 0.0 9831.4 10092.0 14029.0 18174.0 15678.0 16801.0 14815.0 16509.0 13344.0 17008.0 True False 12957.580694176393 13354.04164018368 13842.96629361423 13984.26508550098 13501.380321978926 15750.430814047893 16133.50629954211 13957.913389079633 14049.336597684069 16412.555096832304 0.7894919845038183 0.813647939726403 0.8434376129702063 0.8520468021581846 0.8226251331570398 0.9596574525491035 0.982997845512546 0.850441220561299 0.856011542066089 1.0 14.00251223379287 -6.74944038255597 24.841803171704463 0.9237977014639683 0.826271129764052 0.5453836017776688 0.04801867222818628 186.73075766242383 386592.3144594113 0.016853824045350033 0.016727354991695323 1.7805723187858496e-07 6.74944038255597 -0.0975265716999163 DAPTS(ph)PASVASSSST(ph)PSSK ddPTM_PC-9_Lapatinib_30min_R1 1 DAPTSPASVASSSSTPSSK 19 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 2 DAPT(0.074)S(0.926)PAS(0.003)VAS(0.01)S(0.002)S(0.003)S(0.061)T(0.897)PS(0.019)S(0.004)K 142.97 1.2627e-08 0.0 24242.0 18691.0 22982.0 23548.0 21333.0 21356.0 17779.0 16201.0 23278.0 15458.0 True False 23896.304634561675 18647.722137871624 21092.50867308548 25279.798473825198 20078.234882291705 20442.65366326751 18699.50962668489 16953.757604658287 20656.186511792985 18129.894703509708 1.3180608616516492 1.02856207621888 1.163410434424765 1.3943709484937805 1.1074656091855197 1.12756604478845 1.0314185455839913 0.9351271963745197 1.1393439868017667 1.0 14.146082925637284 -6.919359564903504 1.9282449506154027 1.0223266569501424 1.2058510767144441 0.39139303416129134 0.10511853026221472 0.3724811196599441 2.8216875300642545 0.046181422106745 0.0378084491151746 1.2040386693193425e-07 6.919359564903504 0.18352441976430178 DAPTS(ph)PASVASSSSTPSSK ddPTM_PC-9_AZD4547_30min_R2 3 DAPTSPASVASSSSTPSSK 19 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 DAPT(0.109)S(0.89)PAS(0.001)VASSSSTPSSK;DAPT(0.05)S(0.854)PAS(0.076)VAS(0.014)S(0.005)SSTPSSK;DAPT(0.028)S(0.954)PAS(0.018)VASSSSTPSSK 218.11 6.458e-28 195364000.0 97977.0 94050.0 125070.0 155807.0 149417.0 132409.0 109700.0 135107.0 97243.0 116438.0 True False 129131.64795179937 124449.82325200917 123411.4900807138 119888.10334415389 128673.02867515809 124129.44429839098 119463.08748294106 114229.31759999864 102383.06645448094 112361.54106096906 1.1492513072754191 1.1075838056055214 1.0983428040894248 1.0669852176475652 1.1451696680213577 1.104732483430754 1.0632026434927464 1.016622916715036 0.9111931492549248 1.0 16.777788790999978 -7.773848080463503 1.9710690388567962 0.9568785895723336 1.1099916956988984 0.799045316807131 0.031135660797915708 0.14165550882604944 1.0712337495549689 0.02199127650351892 0.00891199560264377 1.6832627763089834e-08 7.773848080463503 0.1531131061265648 DAPTS(ph)PASVASSSSTPSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DAPTSPASVASSSSTPSSK 19 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 DAPT(0.024)S(0.976)PASVASSSSTPSSK;DAPT(0.008)S(0.991)PASVASSSSTPSSK;DAPT(0.037)S(0.962)PAS(0.001)VASSSSTPSSK 266.29 2.0115999999999997e-78 156139000.0 173880.0 188162.0 184258.0 224721.0 240101.0 221293.0 216646.0 192366.0 208968.0 169043.0 True False 203314.44971345674 206841.47984066347 188651.40952235638 212130.61092531195 193054.93262945005 209688.00551593807 196123.72249878847 187316.59632862464 212023.76167138398 199689.15775634866 1.0181546759866227 1.0358172780369064 0.9447253503494665 1.0623040995753197 0.9667772391779358 1.05007206135743 0.9821450733849527 0.9380408953258221 1.061769021681615 1.0 17.60739647734495 DAPTS(ph)PASVASSSSTPSSK ddPTM_PC-9_Lapatinib_30min_R1 3 DAPTSPASVASSSSTPSSK 19 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 DAPT(0.007)S(0.991)PAS(0.002)VASSSSTPSSK;DAPT(0.007)S(0.993)PASVASSSSTPSSK;DAPT(0.008)S(0.991)PAS(0.001)VASSSSTPSSK 300.28 9.329999999999998e-122 128340000.0 193084.0 168523.0 194019.0 171350.0 182042.0 182299.0 153526.0 164480.0 192666.0 131004.0 True False 190330.58675273115 168132.79534752187 178067.50675499838 183951.65060684306 171334.64746834224 174502.49672972466 161474.82507151287 172122.34126376093 170965.92621707657 153647.8668481424 1.2387453900732903 1.0942735411595113 1.1589325020111805 1.1972287958195433 1.1151124384803892 1.1357300319840684 1.0509408843996917 1.1202390556705726 1.1127126573520896 1.0 17.22926821202197 -14.52287873816458 0.04383680286049395 0.3809940421471069 1.4693416756253652 0.5915160379309812 0.041261507547205874 518.103589446889 1.684112358805792 39.80811722643002 10.640870644421879 3.0000000491539086e-15 14.52287873816458 1.0883476334782582 DAQELYAAGENR ddPTM_PC-9_AZD4547_30min_R2 2 DAQELYAAGENR 12 0 P50995;P50995-2 P50995 ANXA11 Annexin A11 0 ; 165.35 0.0021785999999999997 10534700.0 19922.3 17483.9 34676.0 39250.0 37324.0 29853.0 22405.7 32874.0 27424.0 29036.0 False True 26257.176990417465 23135.228758700698 34216.17358310408 30201.518906455 32142.206859136448 27986.287190748888 24399.76389440773 27794.07866936846 28873.576652794378 28019.458477870558 0.9371050839956482 0.8256843642061331 1.221157561275769 1.077876609582152 1.1471387601770386 0.9988161338968108 0.8708149700208653 0.9919563110514752 1.030483036479752 1.0 14.774141453132595 -6.993436950198249 24.98310278853851 0.9672393031963035 1.0448780282996564 0.08122808027873585 0.10828809854282613 437.7235022615601 1666239.925767514 0.041096583404573075 0.036159424360283035 1.0152267439892532e-07 6.993436950198249 0.0776387251033529 DAQELYAAGENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DAQELYAAGENR 12 0 P50995;P50995-2 P50995 ANXA11 Annexin A11 0 124.38 0.0014937000000000001 3428600.0 8503.2 10025.0 9629.1 10112.0 9994.3 10223.0 10150.0 8694.0 9667.6 9076.8 False True 9942.623814144616 11020.215747083112 9858.694262565103 9545.457423546322 8035.988659682853 9686.887883437037 9188.518520363652 8465.791712054439 9808.970360697687 10722.351988090739 0.9272801177566113 1.027779703494458 0.9194525859172599 0.890239141015741 0.7494613745760617 0.9034293869662378 0.8569499052604589 0.7895461482198449 0.9148151796912152 1.0 13.388333780622354 -5.636147055701272 2.8261208539563127 0.8579293410279737 0.9770061184089154 0.25369871315982717 0.0693523071006228 0.28837835844948945 4.611860848242275 0.018748072469828847 0.03680251012844737 2.3112820384576427e-06 5.636147055701272 0.11907677738094169 DAQELYAAGENR ddPTM_PC-9_Lapatinib_30min_R1 2 DAQELYAAGENR 12 0 P50995;P50995-2 P50995 ANXA11 Annexin A11 0 ; 131.69 0.00050263 13487500.0 35066.0 33346.0 39591.0 33762.0 33575.0 34092.0 35734.0 27943.0 36198.0 35916.0 False True 34565.95240968317 33268.78938577212 36335.98080567953 36244.970106730354 31600.184510989737 32633.964632333562 37584.13167219518 29241.333790936762 32121.00005816145 42124.03274493823 0.8205755754436102 0.7897816808569881 0.862595018518159 0.8604344775390879 0.7501699730965793 0.7747113109975201 0.8922253930379308 0.6941722310395484 0.7625338308099483 1.0 15.36235593895725 -4.343430329168416 16.897374832903672 0.811898151310088 10.169158953777966 0.0 0.0829091758190907 1857.6085898198235 175367.12657714554 0.019102025311194416 1729.576937178885 4.534920425060923e-05 4.343430329168416 9.357260802467879 DAQHYGGWEHR ddPTM_PC-9_AZD4547_30min_R2 3 DAQHYGGWEHR 11 0 F5H6X6;Q14697;Q14697-2;E9PKU7 F5H6X6 GANAB Neutral alpha-glucosidase AB 0 ;; 150.51 0.00014216 112812600.0 133419.0 134092.0 190756.0 233306.0 175368.0 169062.0 149126.0 209596.0 149838.0 173581.0 False True 175843.46671240317 177434.61668802134 188226.45080224393 179520.90624176784 151021.1802720248 158490.5264141758 162397.92510465847 177207.75423693386 157758.13077966028 167503.98202394464 1.0497867846942672 1.0592859617072095 1.1237132904418774 1.071741125629511 0.9015975527700372 0.9461896039672635 0.9695168027793138 1.0579315912119753 0.9418171966628758 1.0 17.353835867188785 -6.159181611995032 8.136210957960786 0.9713556576024422 1.0791083148175147 0.6029111469065918 0.04237320112601541 0.22352697113853143 16.022194091591377 0.013145475919728356 0.017006520477292703 6.93135891864985e-07 6.159181611995032 0.10775265721507243 DAQHYGGWEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DAQHYGGWEHR 11 0 F5H6X6;Q14697;Q14697-2;E9PKU7 F5H6X6 GANAB Neutral alpha-glucosidase AB 0 ;;; 122.55 0.00027697 103778000.0 141213.0 150909.0 163743.0 172141.0 173141.0 151687.0 166824.0 140586.0 144201.0 111512.0 False True 165117.57181611695 165890.24819716337 167647.25411878573 162496.49785865232 139215.2639530683 143732.26669029784 151021.2230188323 136895.76646317999 146309.66682350988 131728.24287149362 1.2534712998274486 1.2593369848483913 1.2726750958208148 1.233573714462846 1.0568368705022397 1.0911271839442558 1.146460468361062 1.0392286686517749 1.11069322443055 1.0 17.0072051706943 -6.195049189124135 4.791609924485692 1.0804290177070874 1.2595776694906595 0.8428351076718752 0.03823828631895786 0.08154939039968447 3.7089072380618733 0.011081335498742063 0.01433575611390797 6.381911991934519e-07 6.195049189124135 0.1791486517835721 DAQHYGGWEHR ddPTM_PC-9_Lapatinib_30min_R1 3 DAQHYGGWEHR 11 0 F5H6X6;Q14697;Q14697-2;E9PKU7 F5H6X6 GANAB Neutral alpha-glucosidase AB 0 ;; 126.71 0.00016701 94488400.0 132018.0 133931.0 119541.0 95991.0 109116.0 119027.0 116061.0 109011.0 125593.0 89824.0 False True 130135.39911086396 133620.89099819583 109712.80042160442 103050.49835658904 102698.0114103099 113936.49267548889 122070.0706891656 114076.04902422069 111447.3937870785 105349.9587170432 1.2352676801743354 1.2683525710445203 1.0414128468363169 0.9781731251871657 0.974827258225548 1.0815048630584474 1.1587101900725991 1.0828295560192356 1.057877906591423 1.0 16.684830223250515 -5.262798698948406 24.97771624758933 1.050073289665832 1.2518101400148187 0.7063967555710439 0.05280629641608282 67.1086895348484 1233164.1771707633 0.015653300919989965 0.03570839316491405 5.460108854814091e-06 5.262798698948406 0.2017368503489867 DAQPS(ph)FSAEDIAK ddPTM_PC-9_AZD4547_30min_R2 1 DAQPSFSAEDIAK 13 0 P25205;J3KQ69;A0A499FHX9;P25205-2 P25205 MCM3 DNA replication licensing factor MCM3 1 DAQPS(0.951)FS(0.049)AEDIAK 81.128 0.011982 3661100.0 9698.5 8890.4 10716.0 20687.0 14993.0 12057.0 9402.7 13653.0 10652.0 10544.0 True False 12782.421258668126 11764.04793875238 10573.898838289982 15917.931760963951 12911.480748018246 11303.07388399354 10239.522084556493 11543.24256472858 11215.042973510996 10174.85776934382 1.2562751783303274 1.1561879492995653 1.039218343685201 1.5644377662873712 1.268959334932395 1.1108827405970196 1.0063553040915718 1.1344868720924643 1.102230933124312 1.0 13.312721007269817 -6.8386516884049495 4.7755074515942795 1.0710651180373219 1.2562992341885255 0.34508618968929017 0.12917102809772932 0.2766184809469995 11.514028912733204 0.04883558070688268 0.0434282919156351 1.449934259398086e-07 6.8386516884049495 0.18523411615120366 DAQPS(ph)FSAEDIAK ddPTM_PC-9_Lapatinib_30min_R1 2 DAQPSFSAEDIAK 13 0 P25205;J3KQ69;A0A499FHX9;P25205-2 P25205 MCM3 DNA replication licensing factor MCM3 1 DAQPS(0.901)FS(0.099)AEDIAK;DAQPS(0.979)FS(0.021)AEDIAK 95.094 0.0036025 4706900.0 29213.0 25084.0 31229.0 26607.0 28515.0 26997.1 26852.0 25227.5 34896.0 23683.0 True False 28796.41726299191 25025.919539156366 28661.47216742609 28563.767538350057 26837.803762646978 25842.496966313873 28242.265172154934 26399.66174751661 30965.64500882927 27776.574994386134 1.036715911476195 0.900972115684324 1.0318576776733202 1.0283401587173013 0.9662027722305976 0.9303701760039474 1.0167655723523479 0.950428976677369 1.1148114918807546 1.0 14.761581097542525 -8.249013554817443 24.97006950890783 1.0574057541436193 0.981982285154103 0.2562234900199988 0.050896128814934945 852.177070952273 1712483.3921533236 0.03329504940635337 0.012374414182768781 5.636200643376398e-09 8.249013554817443 -0.07542346898951624 DAQRLS(ph)PIPEEVPK ddPTM_PC-9_AZD4547_30min_R2 2 DAQRLSPIPEEVPK 14 1 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 DAQRLS(1)PIPEEVPK;DAQRLS(1)PIPEEVPK 86.179 0.0031156 178701000.0 400640.0 480030.0 475360.0 396810.0 444970.0 478900.0 521980.0 571010.0 508470.0 448390.0 True False 528035.1861703136 635190.3100017217 469056.4158052942 305331.5851533867 383193.59624129155 448954.307294062 568435.2087907523 482773.5250044446 535346.686137921 432692.00257929426 1.220348846344917 1.4679964182728753 1.0840422587180494 0.7056557166143422 0.8856036024633209 1.0375840196209485 1.3137178533513156 1.115744044555047 1.2372465470743579 1.0 18.72298093019588 -5.361494099439345 6.453707236931673 1.040728115474195 1.3419910971490703 0.32961394008888767 0.16974983971914548 0.2782291241170862 15.024143845388629 0.04957397560178798 0.10460658754704358 4.350166709632539e-06 5.361494099439345 0.3012629816748753 DAQRLS(ph)PIPEEVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DAQRLSPIPEEVPK 14 1 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 DAQRLS(1)PIPEEVPK;DAQRLS(1)PIPEEVPK;DAQRLS(1)PIPEEVPK;DAQRLS(1)PIPEEVPK 114.9 7.868e-05 52138000.0 248257.0 345256.0 263890.0 273635.0 290301.0 206104.0 297275.0 210532.0 205842.0 203749.0 True False 290282.0068007454 379530.7339625868 270182.1384083975 258304.118086639 233418.602993165 195295.54341464434 269114.9599153798 205005.7580770923 208852.0498351956 240687.08082380355 1.2060556212954698 1.5768637546459112 1.1225452462327463 1.0731947772291612 0.9698011301405932 0.8114085008061219 1.1181113626634038 0.8517522310521021 0.8677326972447142 1.0 17.876799179890092 -5.639551916246379 1.938558555470569 0.9382319345946444 1.3910985432983618 0.6524280853557421 0.12503653797658296 0.18849374051759452 1.422974081165577 0.03587704362071078 0.08213533882860247 2.293232477439389e-06 5.639551916246379 0.4528666087037174 DAQRLS(ph)PIPEEVPK ddPTM_PC-9_Lapatinib_30min_R1 2 DAQRLSPIPEEVPK 14 1 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 DAQRLS(1)PIPEEVPK;DAQRLS(1)PIPEEVPK 82.24799999999999 0.034755 112123000.0 205105.0 382174.0 316303.0 301291.0 365259.0 355573.0 382144.0 396853.0 299474.0 283685.0 True False 202180.16508834987 381289.0995837004 290297.78830488917 323448.9452173125 343775.1837468233 340365.97167114745 401929.5464750471 415292.23916310363 265744.0845189743 332719.57426349865 0.6076593646042371 1.1459773607480543 0.8724998790572707 0.9721368090028745 1.0332280104282927 1.0229815075490365 1.2080129260947459 1.2481749535848203 0.798702886979884 1.0 18.343947218512042 -4.752685541496941 24.99763434300799 1.0394430356570992 0.6076585446397933 0.48131757425007726 0.1324974606502306 299.64209733000695 855600.298618151 0.03333064544849323 0.38746271775977104 1.7673170142632525e-05 4.752685541496941 -0.43178449101730587 DARS(ph)PSGPSGSLENGTK ddPTM_PC-9_AZD4547_30min_R2 1 DARSPSGPSGSLENGTK 17 1 Q14134-2;Q14134;E9PM74;E9PI31;E9PLI4;E9PJ94;E9PJD4 Q14134-2 TRIM29 Tripartite motif-containing protein 29 1 DARS(0.972)PS(0.025)GPS(0.003)GS(0.001)LENGTK 55.588 0.024406999999999998 5858000.0 11855.0 8919.2 18940.0 32728.0 25895.0 20098.0 15186.0 18084.0 11389.0 19453.0 True False 15624.643400681609 11802.156975537686 18688.84322482383 25183.0652425595 22299.926230236273 18841.26888284831 16537.52458081987 15289.533328979101 11990.999288895673 18771.95639103238 0.8323396387254401 0.6287121453774385 0.9955724824585542 1.3415258760450666 1.1879383142446065 1.0036923424693784 0.8809696888450088 0.8144880059642116 0.6387719553100996 1.0 14.196291393519932 -10.530309192063017 4.5164128185271295 1.0000021044587355 0.9360273589295912 0.00877625658786052 0.21151124525516493 335906871.0868144 53.88026632980124 7351.503081824085 0.05764258125561343 2.949108887462084e-11 10.530309192063017 -0.06397474552914428 DAS(ph)EETSTSVMQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DASEETSTSVMQK 13 0 Q9H0W8-2;Q9H0W8;M0QZH1;M0QX70;M0QYR7;M0R2N0;M0QZC7 Q9H0W8-2 SMG9 Protein SMG9 1 DAS(1)EETSTSVMQK 86.262 0.006765100000000001 4274100.0 33703.0 38269.0 57328.0 47782.0 57437.0 57855.0 47865.0 47999.0 50356.0 42795.0 True False 39408.25223540739 42068.093408989866 58694.91693765069 45104.92945133414 46182.632164954426 54820.981952093294 43330.88068740942 46739.07710914434 51092.361235807526 50553.39473496637 0.7795372089651142 0.8321517007816794 1.1610479819479473 0.8922235526971707 0.9135416603983508 1.0844174212137558 0.8571309783364294 0.9245487341489299 1.0106613315221809 1.0 15.625520354029035 -5.022617978577549 24.45718704216453 0.9731925789762994 0.7926907174788538 0.3950409561299505 0.08712457292206524 486.1731752695234 525710.7669908311 0.021629844452674362 0.05828045392993255 9.492530941460768e-06 5.022617978577549 -0.18050186149744563 DAS(ph)EETSTSVMQK ddPTM_PC-9_Lapatinib_30min_R1 3 DASEETSTSVMQK 13 0 Q9H0W8-2;Q9H0W8;M0QZH1;M0QX70;M0QYR7;M0R2N0;M0QZC7 Q9H0W8-2 SMG9 Protein SMG9 1 DAS(1)EETSTSVMQK;DAS(0.985)EET(0.009)S(0.003)T(0.003)S(0.001)VMQK;DAS(1)EETSTSVMQK 156.08 0.00019967 10644400.0 70540.0 77388.0 91474.0 70976.0 75317.0 83101.0 71216.0 81217.0 84468.0 59712.0 True False 69534.08666454829 77208.81284070473 83953.36081985112 76195.81180899523 70887.00213891923 79546.96394789247 74903.21601743579 84990.63831723532 74954.3243525272 70033.13963876142 0.9928740453906921 1.1024611096825905 1.1987662020136711 1.0879965142505612 1.0121922636135139 1.135847462475685 1.0695395980216615 1.213577439989501 1.0702693716024982 1.0 16.095750145589754 DAS(ph)PINR ddPTM_PC-9_AZD4547_30min_R2 2 DASPINR 7 0 Q13523;H0YDJ3 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 DAS(1)PINR;DAS(1)PINR 78.264 0.028586 12018400.0 68898.0 96154.0 73407.0 59748.0 67215.0 87160.0 85220.0 98681.0 95563.0 73758.0 True False 90806.13083257388 127233.90010604661 72433.57521671824 45974.021697398086 57883.357465353525 81709.87142148758 92804.41490698456 83432.11891379065 100614.26508426879 71175.75487018802 1.2758014438791438 1.7876016958035603 1.0176720338101684 0.6459225024201931 0.8132454312697144 1.1480014728401817 1.3038767917002552 1.172198581749587 1.4136030628374987 1.0 16.119098268419016 -5.27881417944756 24.542285260103714 1.0581001294595487 1.5317015703872028 0.3783746639967568 0.2395231325076901 618.5023749665579 873647.9239855541 0.06848740641859515 0.14313804088275736 5.262423803099768e-06 5.27881417944756 0.4736014409276541 DAS(ph)PINR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DASPINR 7 0 Q13523;H0YDJ3 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 DAS(1)PINR 80.755 0.024942 5607000.0 31280.0 58617.0 37651.0 23444.0 32229.0 19971.0 29122.0 17599.0 13478.0 22584.0 True False 36575.08619183879 64436.10837374271 38548.742632212656 22130.508686473517 25913.958807812323 18923.68560306379 26363.35333497833 17137.04489768186 13675.09025212911 26678.300425154357 1.3709676257095067 2.415300350729516 1.4449474673381342 0.8295321791041519 0.9713496885048437 0.709328754136867 0.9881946343973594 0.6423589443322908 0.5125922579099222 1.0 14.70337914028849 -5.613862345961324 3.4248765462545046 0.8008773779184221 1.9064732193591605 0.7136430341438935 0.2801311158216255 0.11027362783321357 2.5383804470854754 0.07421599660792422 0.14080108837140085 2.43297504297788e-06 5.613862345961324 1.1055958414407385 DAS(ph)PINR ddPTM_PC-9_Lapatinib_30min_R1 1 DASPINR 7 0 Q13523;H0YDJ3 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 DAS(1)PINR 72.243 0.039346 8596600.0 23258.0 64603.0 52004.0 50706.0 63827.0 58674.0 60728.0 62790.0 50402.0 44965.0 True False 22926.336655005165 64453.41572269646 47728.43186124518 54435.08839025738 60072.821348710095 56164.64979577438 63872.19869561393 65707.45262616474 44725.196003410536 52737.14033790362 0.43472847613861576 1.2221636461462062 0.9050250270574769 1.032196437680816 1.1390989531059976 1.0649923267721688 1.2111426271194163 1.2459426545534362 0.8480777629739116 1.0 15.68653172298972 -4.753752355889351 24.999521903931964 1.0813848916786621 0.43472731908803564 0.6942728069413902 0.12724494641036746 153.79046516569477 500112.36497605155 0.030971742439589587 0.32353494215380846 1.7629810497882374e-05 4.753752355889351 -0.6466575725906265 DAS(ph)PKT(ph)ST(ph)S(ph)LGKGS(ph)FLDK ddPTM_PC-9_AZD4547_30min_R2 1 DASPKTSTSLGKGSFLDK 18 2 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 5 DAS(0.669)PKT(0.669)S(0.669)T(0.997)S(0.997)LGKGS(1)FLDK 51.76 0.041736 0.0 5274.6 6140.8 4982.5 6581.4 8141.5 7474.6 7176.1 5431.1 5758.9 6571.5 True False 6951.813081504448 8125.693510110973 4916.428794492335 5064.159911616383 7011.193257519545 7007.212080392978 7814.7589980522525 4591.848289262247 6063.303696972632 6341.43378520893 1.0962525695244498 1.2813653481746885 0.7752866246052516 0.7985827942299543 1.1056164102624229 1.104988606320694 1.2323331383321825 0.7241025365545088 0.9561408196226817 1.0 12.630593352305873 -5.244867244810333 24.918116754865576 0.9663134303243499 1.1888089608828853 0.24636187543550736 0.15845037506640963 1213.502576284217 1824633.610692605 0.04289269041219094 0.11278897831382088 5.690268444560405e-06 5.244867244810333 0.22249553055853544 DAS(ph)PSKEER ddPTM_PC-9_AZD4547_30min_R2 1 DASPSKEER 9 1 Q9BUQ8;F8W1J5;F8VVA2;Q9BUQ8-2 Q9BUQ8 DDX23 Probable ATP-dependent RNA helicase DDX23 1 DAS(0.999)PS(0.001)KEER 107.03 0.012211 22533000.0 23551.0 14624.0 13734.0 13909.0 14716.0 15065.0 14607.0 12784.0 23605.0 24585.0 True False 31039.728108768653 19350.92201209337 13551.878186363814 10702.494941907838 12672.937416650208 14122.983168479948 15906.994702491495 10808.52654709516 24852.712109437387 23724.286633091615 1.3083524317849524 0.8156587513616492 0.5712238431422884 0.451119778960163 0.5341756998911601 0.5952964313279131 0.6704941205820605 0.4555891063977865 1.0475641478202256 1.0 14.534077086969743 -4.797446586928823 2.765145795742624 0.6327843297961376 1.4218041306781914 0.4825502710748212 0.19721723609641328 0.32506831305193884 3.48654489680974 0.04841500753702068 0.584507274102686 1.5942389411398365e-05 4.797446586928823 0.7890198008820538 DAS(ph)PTPSTDAEYPANGSGADR ddPTM_PC-9_AZD4547_30min_R2 2 DASPTPSTDAEYPANGSGADR 21 0 E9PEE2;E7EPF5;O43639 E9PEE2 NCK2 Cytoplasmic protein NCK2 1 DAS(0.99)PT(0.005)PS(0.001)T(0.004)DAEYPANGSGADR;DAS(0.985)PT(0.007)PS(0.004)T(0.004)DAEYPANGSGADR 146.18 1.2482e-06 29602000.0 32045.0 33830.0 39818.0 47969.0 56041.0 47958.0 33898.0 49057.0 43748.0 43962.0 True False 42234.64342259318 44764.88591829311 39289.98730338096 36910.48816366221 48260.67448807383 44959.178678656564 36914.85633087263 41476.36786771332 46060.42996668785 42422.903760991394 0.9955622948523547 1.0552056071054525 0.9261503532322745 0.8700603893503879 1.137608937850463 1.0597855095434867 0.8701633565408243 0.9776880927668032 1.0857443947304999 1.0 15.37255575332236 -6.240229056445104 24.99763480929854 1.0150304192406416 0.9658780169440672 0.1146291085975003 0.08015965097938964 2520.0719550712724 2970054.7618195154 0.025520889863791956 0.03290800522536631 5.751365177019969e-07 6.240229056445104 -0.04915240229657447 DAS(ph)PTPSTDAEYPANGSGADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DASPTPSTDAEYPANGSGADR 21 0 E9PEE2;E7EPF5;O43639 E9PEE2 NCK2 Cytoplasmic protein NCK2 1 DAS(0.999)PT(0.001)PSTDAEYPANGSGADR;DAS(1)PTPSTDAEYPANGSGADR 292.65 1.2665999999999996e-131 22987000.0 42048.0 42908.0 42643.0 51640.0 56757.0 43270.0 49021.0 47390.0 52280.0 40947.0 True False 49165.895914144414 47167.62267090695 43659.77084447809 48746.77821913887 45635.873283533554 41000.84502751839 44377.37599869423 46146.06271385552 53044.49609595714 48370.36696372637 1.0164466180505645 0.9751346874477639 0.9026140090526743 1.0077818565175405 0.9434675845597068 0.847643869608546 0.9174496449856058 0.9540151462663311 1.0966320792177568 1.0 15.561835862438455 -8.161939949061946 6.565080450350551 1.0473571615261241 0.9423128338228065 0.38702697277270304 0.05171406164549554 0.23699901410950056 12.96321931324261 0.03711053251402274 0.013741635426074567 6.887475245300281e-09 8.161939949061946 -0.10504432770331762 DAS(ph)PTPSTDAEYPANGSGADR ddPTM_PC-9_Lapatinib_30min_R1 2 DASPTPSTDAEYPANGSGADR 21 0 E9PEE2;E7EPF5;O43639 E9PEE2 NCK2 Cytoplasmic protein NCK2 1 DAS(0.997)PT(0.003)PSTDAEYPANGSGADR;DAS(0.988)PT(0.012)PSTDAEYPANGSGADR 233.38 5.855699999999998e-51 26750000.0 23654.1 25990.0 25324.5 20229.5 23370.0 19643.6 17476.1 18725.1 20581.2 18352.1 True False 23316.788196369318 25929.82175182085 23242.417365396963 21717.244913633738 21995.422547187787 18803.489019468136 18380.92694678597 19595.13650533836 18263.128526355937 21524.236032363868 1.083280640544462 1.2046802364010847 1.0798254270418535 1.0089670490966398 1.021890975090379 0.8735961170094579 0.8539641973423998 0.9103754705103163 0.8484913703276379 1.0 14.393674411973905 -6.14249072615885 1.1116406012758175 0.889179766680976 1.144766875566548 0.7407084650506844 0.05641228482748866 0.23286950208370794 0.5929044545719521 0.022596323343592788 0.03857314694873971 7.202931320756452e-07 6.14249072615885 0.2555871088855721 DAS(ph)TLIR ddPTM_PC-9_AZD4547_30min_R2 1 DASTLIR 7 0 A0A087WUR6;Q8IU85-2;Q8IU85 A0A087WUR6 CAMK1D Calcium/calmodulin-dependent protein kinase type 1D 1 DAS(0.5)T(0.5)LIR 93.429 0.013921000000000001 10372000.0 82276.0 72856.0 100910.0 133090.0 111150.0 106050.0 102330.0 136560.0 100910.0 90874.0 True False 108438.0565528873 96405.27722326809 99571.86746657739 102408.15672000244 95718.74108865672 99418.6767353003 111437.17176052263 115457.78983661748 106243.89658815207 87692.52891989273 1.2365712095262487 1.0993556510536315 1.1354657995726916 1.167809367358449 1.0915267499708663 1.133718892131842 1.2707715598249043 1.316620597657622 1.2115501502437687 1.0 16.420166315157296 -7.244097813877126 23.85987545117624 1.2261206264239657 1.1403409255210981 0.05692011182188539 0.08698954421227376 753.1482811963618 1036240.8360943041 0.03168347405983935 0.02446886909592563 5.7003587162065384e-08 7.244097813877126 -0.08577970090286757 DASLHGLSQYNS(ph)L ddPTM_PC-9_AZD4547_30min_R2 2 DASLHGLSQYNSL 13 0 Q9Y4B5-4 Q9Y4B5-4 MTCL1 Microtubule cross-linking factor 1 1 DASLHGLS(0.013)QY(0.013)NS(0.974)L;DASLHGLS(0.021)QY(0.029)NS(0.95)L 72.681 0.023029 7756400.0 35200.7 32225.0 77817.0 111760.0 93929.0 81507.0 54358.0 94636.0 60751.0 80955.0 True False 46393.79037995556 42641.101055778745 76785.09573527554 85995.45867478759 80888.57968255904 76410.35440513074 59195.756694600714 80012.1807189374 63962.173834375375 78120.79009078423 0.5938725187756204 0.5458355068634801 0.9829021909026204 1.1008011897326204 1.035429615964692 0.9781052433844334 0.7577465182547345 1.0242111047002365 0.8187599454645157 1.0 16.25341891984292 -5.261884773020462 24.993885327221857 0.9639343325031017 0.5698539810064411 0.7236237962300628 0.09699563531217326 19.465596994624278 1092417.0657944726 0.026264976072985953 0.060670249074341355 5.471611163836414e-06 5.261884773020462 -0.39408035149666054 DASLHGLSQYNS(ph)L ddPTM_PC-9_Lapatinib_30min_R1 2 DASLHGLSQYNSL 13 0 Q9Y4B5-4 Q9Y4B5-4 MTCL1 Microtubule cross-linking factor 1 1 DASLHGLS(0.083)QY(0.121)NS(0.796)L;DASLHGLS(0.116)QY(0.101)NS(0.784)L 71.976 0.024656 7075400.0 53535.0 46240.0 98800.0 62689.0 77767.0 88274.0 60941.0 62491.0 97722.0 54294.0 True False 52771.58108288337 46132.93412097715 90677.04537902895 67299.35818437359 73192.89795580454 84498.7267967445 64096.226793396876 65394.559994611496 86715.51930171988 63678.64555779251 0.8287170780821608 0.7244647513601481 1.4239788642604472 1.0568591337781368 1.149410407753997 1.3269554660997995 1.0065576337553441 1.0269464656760277 1.3617676466284119 1.0 15.958522029692364 -5.240835528453182 24.994662418833784 1.1651484325990198 0.7765908268570486 0.5273614586061224 0.14858238180964908 609.796211565724 739745.1539189684 0.036332605755606796 0.09588743167821895 5.743339268742171e-06 5.240835528453182 -0.3885576057419712 DASPS(ph)KEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DASPSKEER 9 1 Q9BUQ8;F8W1J5;F8VVA2;Q9BUQ8-2 Q9BUQ8 DDX23 Probable ATP-dependent RNA helicase DDX23 1 DAS(0.34)PS(0.66)KEER 100.04 0.019057 21035000.0 9074.4 14228.0 11182.0 8414.9 24839.0 24629.0 12290.0 13268.0 20424.0 24217.0 True False 10610.516692430361 15640.461810423783 11448.621287971146 7943.440434473895 19971.97625825345 23337.411883123434 11125.802228105338 12919.729058608029 20722.662361588147 28607.350398333478 0.3709017628227631 0.5467287809826288 0.4001985898224984 0.2776713090820407 0.6981414210040549 0.8157837604031639 0.3889141102964038 0.45162270810514027 0.7243824427303602 1.0 14.804098261544642 -14.522878742467102 0.14353225558609672 2.7111653361939756 0.35180178348486596 0.5142958551383773 0.1537621273147476 124.90260196743297 1.0826928357101748 60.771138987845596 0.9470820690288897 3.000000019433146e-15 14.522878742467102 -2.3593635527091097 DASS(ph)SPASTASSASSTSLK ddPTM_PC-9_AZD4547_30min_R2 1 DASSSPASTASSASSTSLK 19 0 A0A669KBK8;Q04724 A0A669KBK8 TLE1 Transducin-like enhancer protein 1 1 DASS(0.929)S(0.071)PASTASSASSTSLK 341.3 4.5906999999999985e-200 59946000.0 53356.0 52302.0 62208.0 83591.0 78649.0 69033.0 67611.0 75367.0 62246.0 63784.0 True False 70322.09812625631 69207.59867864508 61383.08127401485 64320.38641807595 67729.94393055994 64716.35559705785 73628.24802013773 63720.76191136744 65536.1964822723 61550.94157433865 1.1425023943999983 1.1243954504751001 0.9972728231927847 1.0449943538295425 1.1003884294565753 1.051427548332403 1.1962164369364297 1.0352524312631053 1.0647472614715474 1.0 15.909493306027482 -8.582941866797718 1.6969445369515053 1.0018045205333168 1.0869875323189224 0.1892506087116962 0.05487134006191232 0.7891917829330637 5.01867900653164 0.05367824287728245 0.015383050242391465 2.6125110329571367e-09 8.582941866797718 0.08518301178560561 DASS(ph)SPASTASSASSTSLK ddPTM_PC-9_Lapatinib_30min_R1 2 DASSSPASTASSASSTSLK 19 0 A0A669KBK8;Q04724 A0A669KBK8 TLE1 Transducin-like enhancer protein 1 1 DASS(0.5)S(0.5)PASTASSASSTSLK;DASS(0.5)S(0.5)PASTASSASSTSLK 321.93 2.4152999999999993e-158 98879000.0 109933.0 91813.0 105416.0 88386.0 104519.0 87076.0 85039.0 90289.0 92737.0 66342.0 True False 108365.33526075665 91600.41263947371 96749.10339752774 94886.20128705242 98371.39791226028 83351.96246407002 89441.90332097733 94484.1565561996 82291.98249609696 77809.12630484166 1.3927072620787626 1.1772450995092834 1.2434158818142076 1.2194739331130124 1.2642655506355318 1.0712363243549679 1.1495040179549199 1.214306869171468 1.0576135011938357 1.0 16.247651759729457 -1.5228787486356221 0.08556130447311586 0.8572692952644767 2.092428786281942 0.6403067163295166 0.06548947597691261 115.80726256121271 0.7197095379971382 1.4485684457191765 16.82583761297359 0.029999999768225157 1.5228787486356221 1.2351594910174655 DASSQDCY(ph)DIPR ddPTM_PC-9_AZD4547_30min_R2 2 DASSQDCYDIPR 12 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 DASSQDCY(1)DIPR;DASS(0.001)QDCY(0.999)DIPR 130.1 0.00022612 16454000.0 9720.400000000001 18501.1 18703.4 21903.9 18881.6 15450.7 14220.3 19136.5 15077.9 15238.7 True False 12811.285003119827 24481.218766270562 18455.380695415526 16854.29426688154 16260.215760140161 14484.565286507343 15485.879151628651 16179.393638023048 15874.887011857069 14705.197751299298 0.8712079374782885 1.664800377411279 1.255024312324183 1.1461453665519294 1.1057461473922354 0.9849962939279439 1.053088806660922 1.100249987226013 1.0795425726562855 1.0 13.844038564855728 -5.915272880233256 2.5024015599792873 1.0568445849171038 1.3055484939805022 0.20322624238054887 0.18218749651933158 0.38397733958588476 4.875495760941414 0.05289977591616315 0.08566034863673219 1.215422074572504e-06 5.915272880233256 0.24870390906339845 DASSQDCY(ph)DIPR ddPTM_PC-9_Lapatinib_30min_R1 1 DASSQDCYDIPR 12 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 DASS(0.002)QDCY(0.997)DIPR 136.53 9.233e-05 10784000.0 8558.7 9308.5 8685.6 9425.6 11026.0 11152.0 12188.0 11103.0 15232.0 6837.2 True False 8436.651368526645 9286.946740162532 7971.503495385568 10118.790066879854 10377.472357950051 10675.054956581718 12819.035003657988 11618.88591349428 13516.411759929142 8019.000910003665 1.0520826052035939 1.1581176812908338 0.9940768912298235 1.2618517169959056 1.2941103853728466 1.3312200704784356 1.5985825600376604 1.4489193908183469 1.6855481015181684 1.0 12.969206786682616 -6.355951655588888 1.2414073870044802 1.4622519383422012 1.0764495155841312 0.3915554858560669 0.17864925607118184 0.40898539571452813 1.296604898267327 0.07083011621649729 0.093433501689859 4.406039075349869e-07 6.355951655588888 -0.3858024227580701 DASSS(ph)PASTASSASSTSLK ddPTM_PC-9_AZD4547_30min_R2 3 DASSSPASTASSASSTSLK 19 0 A0A669KBK8;Q04724 A0A669KBK8 TLE1 Transducin-like enhancer protein 1 1 DAS(0.052)S(0.228)S(0.72)PASTASSASSTSLK;DAS(0.02)S(0.109)S(0.802)PAS(0.053)T(0.007)AS(0.007)S(0.002)ASSTSLK;DAS(0.001)S(0.006)S(0.993)PASTASSASSTSLK 157.83 1.2567999999999999e-05 112476000.0 148392.0 135088.0 204377.0 248235.0 227646.0 209472.0 176289.0 228766.0 180729.0 189054.0 True False 195577.56925465574 178752.5542101798 201666.82744244047 191008.25594251888 196041.28235599044 196373.68272604293 191978.3794829545 193415.47121971 190281.96597443396 182435.2770035591 1.072038108346996 0.9798135379633433 1.1054157438997183 1.0469918925756476 1.0745799034918333 1.0764019215549627 1.0523095238823204 1.0601867927985038 1.0430108096402966 1.0 17.47702520085374 -1.8371576522938318 13.907975336215953 1.053554005033647 1.1506353466897101 0.0 0.035356567372447203 0.0 0.0 0.007600687964421692 0.0 0.01454930833436342 1.8371576522938318 0.09708134165606319 DASSS(ph)PASTASSASSTSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DASSSPASTASSASSTSLK 19 0 A0A669KBK8;Q04724 A0A669KBK8 TLE1 Transducin-like enhancer protein 1 1 DAS(0.064)S(0.121)S(0.813)PAS(0.001)TASSASSTSLK;DASS(0.097)S(0.903)PASTASSASSTSLK;DASS(0.206)S(0.794)PASTASSASSTSLK;DAS(0.005)S(0.037)S(0.957)PASTASSASSTSLK 369.65 4.201399999999998e-276 136374000.0 326759.0 324904.0 343299.0 399703.0 424229.0 382825.0 411619.0 379085.0 347543.0 310949.0 True False 382072.8449155711 357158.3219042686 351484.5501287072 377308.93676461006 341104.3728033568 362748.9830751035 372627.46845650853 369134.4204237591 352625.15888824075 367321.59222907067 1.0401589587940727 0.9723314105682521 0.9568850771764947 1.027189647292259 0.9286259779431529 0.9875514828131432 1.0144447708484532 1.0049352617244398 0.9599902819443707 1.0 18.486684178799905 -7.008826242501909 24.84899152455148 0.9960744629374999 0.982407846025363 0.016154281712131957 0.032740641859071294 1681.209198133948 4733189.755493979 0.011758377463009164 0.009838577639696268 9.798819493581151e-08 7.008826242501909 -0.013666616912136886 DASSS(ph)PASTASSASSTSLK ddPTM_PC-9_Lapatinib_30min_R1 2 DASSSPASTASSASSTSLK 19 0 A0A669KBK8;Q04724 A0A669KBK8 TLE1 Transducin-like enhancer protein 1 1 DAS(0.002)S(0.033)S(0.965)PASTASSASSTSLK;DASSS(1)PASTASSASSTSLK 294.93 3.5133999999999992e-121 57622000.0 265930.0 202257.0 232190.0 199616.0 227950.0 204030.0 187570.0 191899.0 223600.0 162062.0 True False 262137.78943441124 201788.68634313348 213100.2344793193 214296.42653945577 214542.42916694307 195304.1125171602 197281.45681294132 200815.32810174202 198415.81338761526 190074.20076595878 1.3791339822977104 1.0616311184262135 1.1211423413623232 1.1274356313265375 1.1287298765554847 1.0275151058382777 1.0379181183871289 1.056510180195412 1.0438860854763117 1.0 17.53620319920126 DASVPLIDVT(ph)NLPTPR ddPTM_PC-9_AZD4547_30min_R2 1 DASVPLIDVTNLPTPR 16 0 Q96A65-2;Q96A65 Q96A65-2 EXOC4 Exocyst complex component 4 1 DASVPLIDVT(0.642)NLPT(0.358)PR 87.824 0.010142 6348100.0 5599.3 4031.8 4620.5 8354.1 7605.9 8231.4 5406.4 8940.7 5045.6 8381.5 True False 7379.760927324891 5335.000503853801 4559.229151018933 6428.191314558367 6549.95207239058 7716.689256755775 5887.559126415421 7559.120251847133 5312.300115203443 8088.066236130046 0.9124258768256499 0.6596138493552294 0.563698295477909 0.7947748110473077 0.8098291830414809 0.9540833409949959 0.7279316161031445 0.9346016750060641 0.6568071971855237 1.0 12.98157909670829 -5.987282287753995 24.807318231359776 0.8395899999104933 0.7021083859287152 0.18392713247548997 0.126422605299707 337.70968794655664 658734.0449238798 0.034268906245037936 0.05079303982028319 1.0297165957613422e-06 5.987282287753995 -0.13748161398177816 DASVPLIDVTNLPT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 DASVPLIDVTNLPTPR 16 0 Q96A65-2;Q96A65 Q96A65-2 EXOC4 Exocyst complex component 4 1 DASVPLIDVTNLPT(1)PR;DASVPLIDVTNLPT(1)PR 199.61 4.9567e-39 6284800.0 14393.0 15675.5 17696.2 26337.7 22444.6 22152.0 19140.6 28071.0 18671.4 22733.2 True False 18969.674607002144 20742.29882389015 17461.536825508327 20265.950178408668 19328.554711996945 20766.83193814588 20844.07631974455 23733.271957408335 19658.332085581427 21937.31758744755 0.8647217022493452 0.9455257572493191 0.7959741092274542 0.9238116783250094 0.8810810453442435 0.9466440851468815 0.950165225837431 1.0818675466041674 0.8961137571728391 1.0 14.4210995087602 -7.008177553603655 1.7306761782627782 0.9916467100570644 0.8812184721826176 0.4111361074513413 0.05674030203770082 0.3439515421733664 2.0753982977016143 0.02545716452974187 0.019201351520204663 9.813466548044659e-08 7.008177553603655 -0.11042823787444678 DASVPLIDVTNLPT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DASVPLIDVTNLPTPR 16 0 Q96A65-2;Q96A65 Q96A65-2 EXOC4 Exocyst complex component 4 1 DASVPLIDVTNLPT(1)PR;DASVPLIDVTNLPT(1)PR;DASVPLIDVT(0.009)NLPT(0.991)PR;DASVPLIDVT(0.003)NLPT(0.997)PR 203.06 1.9881e-16 10252500.0 59281.8 55956.4 59959.100000000006 57102.2 67976.7 56245.0 51147.5 48014.9 43523.100000000006 42291.3 True False 69317.0378710789 61511.38158903554 61388.752340153034 53902.948861830235 54657.1536098239 53295.413186336315 46302.438524167475 46754.55975099176 44159.54299988428 49958.377912253396 1.3874957668326808 1.2312525778373704 1.22879794952462 1.078957146216898 1.0940538082686233 1.0667963095187771 0.926820294395723 0.9358702524952109 0.8839266774723119 1.0 15.608439014703109 -5.377952777032824 0.46322774085521295 0.9179442327710203 1.52365646035985 0.8964416720851726 0.04868849217867082 0.8598289677336826 0.2138201439226652 0.03736485293466338 0.26975215352781934 4.188391050702995e-06 5.377952777032824 0.6057122275888296 DASVPLIDVTNLPT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 DASVPLIDVTNLPTPR 16 0 Q96A65-2;Q96A65 Q96A65-2 EXOC4 Exocyst complex component 4 1 DASVPLIDVTNLPT(1)PR;DASVPLIDVTNLPT(1)PR;DASVPLIDVT(0.003)NLPT(0.997)PR 156.67 2.3426e-05 12539600.0 46410.3 45519.399999999994 48932.7 42711.0 38264.3 33230.7 26336.9 27264.699999999997 41719.0 27548.800000000003 True False 45748.480611393345 45414.00262600358 44909.642291684315 45852.10941971924 36013.66910450828 31809.500425545197 27700.495814558588 28531.517496680844 37020.16689945404 32310.573373531417 1.4158981359603529 1.4055461690818027 1.3899364078903644 1.4191054083020684 1.1146094093771302 0.9844919821696295 0.8573198467982196 0.8830396528974522 1.1457601346616981 1.0 14.979718732003876 -6.429333709933383 2.5129991697922835 0.9593958461745706 1.4104087075060683 0.883100226098124 0.07433976614082224 0.09203316033208299 1.140640790235595 0.026206233258034815 0.0297653745895444 3.7210567204432146e-07 6.429333709933383 0.45101286133149765 DAT(ph)PPVSPINMEDQER ddPTM_PC-9_AZD4547_30min_R2 2 DATPPVSPINMEDQER 16 0 P17275 P17275 JUNB Transcription factor jun-B 1 DAT(0.999)PPVS(0.001)PINMEDQER;DAT(1)PPVSPINMEDQER 93.181 0.014606999999999998 0.0 11756.3 10911.2 12975.7 17068.4 17225.5 15123.0 11178.8 13836.2 12163.8 13268.0 True False 15494.558853769146 14438.03201985456 12803.633739828228 13133.544084151263 14834.036658773308 14177.356419311134 12173.691543794877 11698.133214245785 12806.753635110132 12803.491358464888 1.2101823182412732 1.1276636673253202 1.000011120510754 1.0257783378334664 1.1585930933569888 1.1073039394007114 0.9508103065767585 0.9136674432565375 1.0002547958641834 1.0 13.644249649049787 -7.261216736391324 24.99536068763067 0.9589887510828714 1.1000292600146533 0.5507107562860074 0.06115762100784347 16.756646958699992 1881306.8342446429 0.026240980325258657 0.0190257733629544 5.4800341338146975e-08 7.261216736391324 0.14104050893178188 DATNVGDEGGFAPNILENK ddPTM_PC-9_AZD4547_30min_R2 4 DATNVGDEGGFAPNILENK 19 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 ;;; 241.64 1.0101e-43 17404300.0 80322.8 85049.0 110730.0 105907.0 108238.0 118890.0 102138.0 115504.0 106114.0 101687.0 False True 105863.77958197138 112539.42602615753 109261.64785030314 81491.77739683907 93211.02202387786 111455.78950551507 111228.08413247611 97655.51081787207 111722.96940397545 98126.96908111377 1.0788448942559532 1.146875594752449 1.1134721562630272 0.8304727860235476 0.949902181803126 1.1358323868475284 1.1335118691022923 0.9951954262150705 1.1385551846773434 1.0 16.582362078811066 -6.775739302880943 24.999172931889724 1.0836244738426741 1.0249735019979878 0.07980543868511336 0.09597138135405119 737.6103064950275 1289485.3407088108 0.03704483476155791 0.03282633014843705 1.6759486080427748e-07 6.775739302880943 -0.05865097184468637 DATNVGDEGGFAPNILENK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DATNVGDEGGFAPNILENK 19 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 ;;; 325.61 2.0598999999999993e-176 27337200.0 174952.0 200682.0 201999.0 202707.0 213604.0 147964.0 206464.0 167501.0 156158.0 148768.0 False True 204567.9181404916 220604.38269886654 206815.42224547337 191349.98397496107 171749.82956914417 140204.5073642646 186906.23525008495 163104.27623197922 158441.51532808846 175738.46075316035 1.1640475127856313 1.2552993906594196 1.1768364270355325 1.088833845220304 0.9773035955423637 0.7978020677055649 1.0635476972374913 0.9281080278782746 0.9015756405800838 1.0 17.423070437357765 -6.044106313046774 2.0953519197549952 0.9377585246669308 1.2080960959367624 0.7427747979868783 0.06786645486322591 0.15561976340669378 1.361234304453994 0.021762550528980535 0.033069158959430626 9.034282920701228e-07 6.044106313046774 0.2703375712698316 DATNVGDEGGFAPNILENK ddPTM_PC-9_Lapatinib_30min_R1 4 DATNVGDEGGFAPNILENK 19 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 ;;; 224.36 1.973e-34 121635000.0 219725.0 218177.0 220778.0 225701.0 234209.0 209300.0 233381.0 201246.0 208063.0 227750.0 False True 216591.6812073696 217671.8245612545 202626.48506772553 242299.8044564648 220433.28709261035 200348.72690213026 245464.32623799666 210596.62384464286 184628.7539394788 267116.28404220013 0.810851655802278 0.8148953754046152 0.7585703200173066 0.9070948456971843 0.8252334292647819 0.7500431043375788 0.9189418275945214 0.7884080321039953 0.6911924317961476 1.0 18.027108403202128 -11.00284102016896 2.9205825404295944 1.0057322306001624 0.8105552938989409 0.4401634790726646 0.06511839746767464 23215584.20940762 26341316.74612186 1076458.6193722512 0.015838920371668196 9.934796595875932e-12 11.00284102016896 -0.1951769367012215 DATNVGDEGGFAPNILENKEGLELLK ddPTM_PC-9_AZD4547_30min_R2 1 DATNVGDEGGFAPNILENKEGLELLK 26 1 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 90.46799999999999 6.7429e-07 3368700.0 13638.0 7595.5 13849.0 25230.0 23948.0 16502.0 14272.0 15363.0 11953.0 19040.0 False True 17974.60031197772 10050.596836902021 13665.353211224141 19413.613299614277 20623.233572569923 15470.1273313147 15542.180351472485 12989.001356619438 12584.81117746686 18373.415395324966 0.9782939059088207 0.547018429652407 0.7437568311170513 1.0566142920033248 1.1224496441645473 0.8419843016911818 0.8459058926750833 0.7069453924132381 0.6849467508729492 1.0 14.165332210457072 -10.944954652670589 3.8922954713024573 1.0009190746478065 0.8367182677964254 0.07851162774795983 0.16810589021730887 30044514.1866352 84487299.89573826 144192.92000096265 0.04418431522649639 1.1351293352453576e-11 10.944954652670589 -0.16420080685138105 DATNVGDEGGFAPNILENKEGLELLK ddPTM_PC-9_Lapatinib_30min_R1 1 DATNVGDEGGFAPNILENKEGLELLK 26 1 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 114.57 1.5838e-11 4915000.0 45898.0 18653.0 33301.0 23037.0 24528.0 23260.0 17462.0 13849.0 30542.0 15377.0 False True 45243.48610333762 18609.810124536896 30563.12032557739 24731.217829179182 23085.311263903393 22265.224021708298 18366.096917777795 14492.47509826013 27102.03833848187 18034.893961435442 2.5086638269170383 1.031877989653325 1.6946659287784798 1.3712982112377645 1.2800358745256508 1.2345636225707064 1.0183645635538847 0.8035797232437201 1.502755624537354 1.0 14.138503320181949 -4.756158402041991 24.99997744048292 1.2254353600795016 2.5086658307573058 0.7046973820302082 0.2511077093431217 96.2082609554391 455397.36052103346 0.06433178501580832 0.5341257963471291 1.7532409183201486e-05 4.756158402041991 1.2832304706778042 DATPPVS(ph)PINMEDQER ddPTM_PC-9_AZD4547_30min_R2 1 DATPPVSPINMEDQER 16 0 P17275 P17275 JUNB Transcription factor jun-B 1 DAT(0.001)PPVS(0.999)PINMEDQER 98.552 0.0017921 3847500.0 7328.5 7469.7 10991.0 12727.0 13931.0 11038.0 11024.0 12434.0 11604.0 11668.0 True False 9658.810557730509 9884.134447055096 10845.252158608173 9792.986780189889 11996.921116563868 10347.792115080096 12005.114643682222 10512.611004895274 12217.363749964481 11259.506871462792 0.8578360196405007 0.8778478986594362 0.9632084497497357 0.869752724696159 1.0654925880430919 0.9190271148824967 1.0662202866192276 0.9336653127802138 1.085070943997501 1.0 13.458856023159942 -5.310020296327967 0.5030452359890684 1.0194280904834994 0.7941274939389374 0.4514378241871133 0.06072536325659168 2.4936871984536575 0.7101406310752522 0.03873471551509446 0.3126835296330587 4.89755930569066e-06 5.310020296327967 -0.22530059654456192 DAVAHCHEAER ddPTM_PC-9_AZD4547_30min_R2 2 DAVAHCHEAER 11 0 P49792;J3KQ37;H0YBN8;Q99666;O14715;F8W705;Q99666-2 P49792;Q99666 RANBP2;RGPD8;RGPD5 E3 SUMO-protein ligase RanBP2;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8 0 ; 132.17 5.1223e-05 2382540.0 10555.2 11581.099999999999 12078.8 14520.8 14699.3 11619.8 10455.0 12729.6 11712.5 13646.5 False True 13911.534038201135 15324.464094246063 11918.627219852277 11173.253904123614 12658.555923387215 10893.21206910741 11385.474745981286 10762.532817107527 12331.598838457341 13168.740188671334 1.0564058398060585 1.1637000863172342 0.9050696611134836 0.8484679433295848 0.9612579291584008 0.8272022921735906 0.8645834440393823 0.8172788484631359 0.9364296555160105 1.0 13.684829713717006 -5.307730087242384 7.054269131368754 0.8851394795346188 1.109794014702164 0.6617077708231924 0.06119222149762319 0.11170577772183654 14.491113478975818 0.015142677525141467 0.03222735333978392 4.923454318690219e-06 5.307730087242384 0.2246545351675453 DAVAHCHEAER ddPTM_PC-9_Lapatinib_30min_R1 1 DAVAHCHEAER 11 0 P49792;J3KQ37;H0YBN8;Q99666;O14715;F8W705;Q99666-2 P49792;Q99666 RANBP2;RGPD8;RGPD5 E3 SUMO-protein ligase RanBP2;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8 0 118.9 0.00042803 1028000.0 4481.3 6526.7 5800.6 5981.1 7574.1 5779.5 7140.6 6597.9 6989.4 6377.6 False True 4417.395840230228 6511.587827149256 5323.6970589635175 6420.970046364704 7128.606329253539 5532.3242576725315 7510.305328775869 6904.4625208181515 6202.180170355094 7479.95966238217 0.5905641259599258 0.8705378265469799 0.7117280439007154 0.8584230846399771 0.9530273759502155 0.7396195310377692 1.0040569291498072 0.9230614645613292 0.8291729434781288 1.0 12.868814774689689 -3.4507447159181823 0.38625512501334175 0.9287176280822631 5.680766817807274e-20 0.48063463034878406 0.09163664807090836 14.957169879462406 0.7872896379036013 0.06993299551670333 7.938861170977776 0.0003542054866055805 3.4507447159181823 -0.9287176280822631 DAVIQDLER ddPTM_PC-9_Lapatinib_30min_R1 1 DAVIQDLER 9 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;A0A3B3ISX8;Q8WX93-4 Q8WX93-3 PALLD Palladin 0 94.69200000000001 0.026105 2526600.0 10991.0 12063.0 11423.0 12185.0 13382.0 12587.0 12881.0 12353.0 11308.0 11362.0 False True 10834.26632449745 12035.06886464851 10483.845034055148 13081.125547968415 12594.89707002427 12048.683351730097 13547.915152782947 12926.96547684363 10034.373961481013 13325.906561086644 0.8130228344940447 0.9031332172020817 0.7867265904947376 0.9816311924448712 0.9451437327951094 0.9041548728034607 1.0166599240868608 0.9700627433927855 0.7529974726659627 1.0 13.701946062379683 -5.765815582529315 24.999747812798 0.9394987960521582 0.841178112955356 0.28875504239261196 0.07482210534169394 145.6040929219967 831793.648257437 0.020567560883059038 0.03174225157976873 1.7146852716078655e-06 5.765815582529315 -0.0983206830968022 DAVLLLFANK ddPTM_PC-9_Lapatinib_30min_R1 1 DAVLLLFANK 10 0 C9JPM4;C9JAK5;P18085;U3KQF2 C9JPM4 ARF4 ADP-ribosylation factor 4 0 130.56 0.00096263 2141300.0 5865.8 5446.6 8261.6 8439.8 7361.2 7516.0 8638.2 7564.5 8469.6 6409.8 False True 5782.152616344025 5433.988732338107 7582.363138698235 9060.491046347466 6928.228688676033 7194.558200651736 9085.44372896279 7915.974285564937 7515.664459158081 7517.725389478364 0.7691359176855 0.7228235205216983 1.0085980460672768 1.2052170805584788 0.9215857629453481 0.9570126371895779 1.2085362604064478 1.052974653296588 0.9997258571956927 1.0 12.876080501656006 -5.307892860294461 5.08004314905228 1.0522259794121833 0.7446338567040746 0.636932205626215 0.09022582794543983 0.11318965458961867 6.9548012586078265 0.02424374964107487 0.05421735722993239 4.9216093596695145e-06 5.307892860294461 -0.30759212270810876 DAVLLVFANK ddPTM_PC-9_Lapatinib_30min_R1 2 DAVLLVFANK 10 0 P61204-2;P84077;P61204;F5H423;C9J1Z8;P84085 P61204-2 ARF3;ARF1;ARF5 ADP-ribosylation factor 3;ADP-ribosylation factor 1;ADP-ribosylation factor 5 0 ; 151.44 0.0005761 14996500.0 155631.0 142014.0 154804.0 153189.0 153323.0 127190.0 147448.0 148229.0 133638.0 151437.0 False True 153411.67340076985 141685.1753083142 142076.61268072078 164455.03008352345 144304.8425846159 121750.38019437142 155082.13597139518 155116.26047656898 118586.28116947296 177612.6836728812 0.8637427813619233 0.7977199171724887 0.7999237990367337 0.925919403292217 0.8124692426267814 0.6854824648593545 0.8731478673956544 0.8733399961584665 0.6676678642381175 1.0 17.438375085508717 -10.854538952192819 3.925607116778127 1.0004427891876346 0.8137130206147195 0.34680671575207667 0.07771798932048715 19150831.13948491 26476962.696122866 58654.07193436093 0.01856419214828239 1.3978515353636002e-11 10.854538952192819 -0.18672976857291512 DAVS(ph)SPQKR ddPTM_PC-9_AZD4547_30min_R2 1 DAVSSPQKR 9 1 O00472;D6RC27 O00472 ELL2 RNA polymerase II elongation factor ELL2 1 DAVS(0.61)S(0.39)PQKR 88.134 0.015209 4661300.0 14840.0 10656.0 17922.0 22938.0 19286.0 13894.0 15067.0 18529.0 15991.0 18510.0 True False 19558.811308824555 14100.343610562551 17684.342569973236 17649.99848856727 16608.471800592266 13025.205983595113 16407.93381135342 15665.76880406182 16836.251613726472 17861.970534005526 1.0949974008516357 0.7894058264018738 0.9900555225027315 0.9881327737589364 0.9298230432623962 0.7292143920402172 0.9185959511083104 0.8770459437404966 0.9425752652359214 1.0 14.124603627019702 -4.737293610957756 24.92473422378577 0.903981689534406 1.0949982737164834 0.3098785347159573 0.08395071495595449 2729.4899509529396 2817395.235968116 0.02104167575051469 1.3405718663041275 1.8310760788076437e-05 4.737293610957756 0.19101658418207734 DAVSS(ph)PQKR ddPTM_PC-9_AZD4547_30min_R2 1 DAVSSPQKR 9 1 O00472;D6RC27 O00472 ELL2 RNA polymerase II elongation factor ELL2 1 DAVS(0.134)S(0.866)PQKR 80.102 0.028173 4892200.0 17286.0 15899.0 27353.0 32638.0 27433.0 25238.0 19205.0 25524.0 23795.0 26194.0 True False 22782.588428863954 21038.040828109424 26990.281347867283 25113.813352073335 23624.401478048738 23659.863870301826 20914.20779498522 21579.85228317091 25052.75512154472 25276.95603283308 0.9013185131655446 0.8323011995899511 1.06778210607356 0.9935457940209322 0.9346220900713763 0.9360250435048129 0.8274021511062907 0.8537361957325922 0.9911302250556935 1.0 14.625535117560153 -7.0191613508671615 24.05062036419333 0.9024263686554304 0.9476492856121379 0.012613987652771108 0.07586050825144706 1446.363196282731 1815416.8737484692 0.02979727894126337 0.0234834616516418 9.568385166802205e-08 7.0191613508671615 0.04522291695670755 DAVSS(ph)PQKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DAVSSPQKR 9 1 O00472;D6RC27 O00472 ELL2 RNA polymerase II elongation factor ELL2 1 DAVS(0.132)S(0.868)PQKR;DAVS(0.176)S(0.824)PQKR 80.834 0.026605 7139600.0 30730.0 32604.0 41298.0 44943.0 47698.0 41602.0 37463.0 38757.0 38529.0 30889.0 True False 35931.98205483396 35840.709647670585 42282.70094353717 42424.98941717193 38351.919302957955 39420.317883864576 33914.23343136783 37739.66981643592 39092.41373529329 36488.93118281054 0.9847364910420026 0.9822351185927494 1.1587815694490937 1.1626810663382157 1.0510562534927042 1.0803363268265576 0.9294389375631913 1.0342772066235413 1.0713499263499724 1.0 15.155171272323253 DAVSS(ph)PQKR ddPTM_PC-9_Lapatinib_30min_R1 2 DAVSSPQKR 9 1 O00472;D6RC27 O00472 ELL2 RNA polymerase II elongation factor ELL2 1 DAVS(0.042)S(0.958)PQKR;DAVS(0.05)S(0.95)PQKR 112.94 0.0031359 8781700.0 47230.0 42293.0 52934.0 50027.0 50993.0 44652.0 41632.0 37707.0 54234.0 40931.0 True False 46556.49153907877 42195.07315697416 48581.97085114901 53706.152465179766 47993.69199609533 42742.33804889591 43787.50125305954 39459.00487617122 48125.595810661616 48005.868812870765 0.9698083315720889 0.8789565567796018 1.0120006585137313 1.118741391277158 0.9997463473305128 0.8903565148567072 0.9121280863334725 0.821962102800063 1.0024940075193214 1.0 15.550923168501063 -6.75277845395388 24.974003733989335 0.9134320193183341 0.9970810422233716 0.1778091112351724 0.07352218395284196 299.0810105573114 862406.5177708798 0.025716110217309796 0.02533207070756611 1.7669389569563242e-07 6.75277845395388 0.0836490229050375 DAVTYTEHAK ddPTM_PC-9_AZD4547_30min_R2 4 DAVTYTEHAK 10 0 P62805 P62805 HIST1H4A Histone H4 0 ;;; 154.24 0.00010571 81757100.0 814221.0 696204.0 733058.0 820495.0 630808.0 569940.0 515899.0 788504.0 379676.0 468143.0 False True 1073126.341151105 921238.3279887489 723337.1719484123 631342.5542713843 543231.1977386705 534301.5617021882 561813.0115712108 666658.8248193621 399744.89823608345 451753.4560616402 2.3754690235389826 2.0392502052337353 1.6011768415773127 1.397537851232819 1.2024948352903104 1.182728221628225 1.243627478733784 1.4757138343362202 0.8848740233689317 1.0 18.78517611265766 -5.046079339504614 0.871165730544694 1.173929624033379 2.7997784989054053 0.8905802404774094 0.14517661937854362 0.492854222840223 0.3817707060956025 0.05308308883133937 0.7091535434029982 8.993332709593607e-06 5.046079339504614 1.6258488748720263 up DAVTYTEHAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DAVTYTEHAK 10 0 P62805 P62805 HIST1H4A Histone H4 0 ;;; 178.54 0.00010778 120511000.0 403301.0 639355.0 495051.0 751884.0 704955.0 677501.0 814887.0 633065.0 515849.0 465144.0 False True 471571.8937421614 702825.9390500061 506854.8933313719 709758.3771208168 566824.1283118102 641971.654887653 737695.0040890222 616447.7145378137 523392.31573457166 549470.9251221225 0.8582290202841075 1.279095775438527 0.9224416982913536 1.2917123448580463 1.031581658639774 1.1683450853108774 1.342555120500809 1.1218932364816305 0.9525386909566602 1.0 19.067683618410435 -4.740144649606466 24.63865623399766 1.1315318603941085 0.8582277914724845 0.24181470515051506 0.1401641128045367 1943.8649579929195 2248972.646987838 0.03340215608946996 1.5027975959315565 1.8190948753566883e-05 4.740144649606466 -0.27330406892162395 DAVTYTEHAK ddPTM_PC-9_Lapatinib_30min_R1 2 DAVTYTEHAK 10 0 P62805 P62805 HIST1H4A Histone H4 0 ; 150.15 0.00013385 20090500.0 349960.0 235410.0 152585.0 131726.0 124150.0 126892.0 180796.0 114830.0 148362.0 95175.0 False True 344969.5062251954 234864.92260854755 140040.05029513332 141413.56946505452 116847.74108829108 121465.1249596994 190156.73223837774 120165.42100752488 131651.90923887913 111625.87193728425 3.0904081664778635 2.1040366228046468 1.2545483216813147 1.2668529885661826 1.0467800973052257 1.0881449152571299 1.7035184490672124 1.0765015217532947 1.1794031881143674 1.0 16.768311919074982 -4.891562530233893 1.791723231986221 1.2016181978901024 3.479790523180449 0.9090599340633813 0.18962146294026308 0.18781937108058164 0.7427803611566864 0.053442136461098244 0.6827708221654463 1.2836229396155136e-05 4.891562530233893 2.2781723252903467 up DAYGTSS(ph)LS(ph)SSSNS(ph)GS(ph)YK ddPTM_PC-9_Lapatinib_30min_R1 1 DAYGTSSLSSSSNSGSYK 18 0 A0A3B3IRY9;O15079;O15079-2 A0A3B3IRY9 SNPH Syntaphilin 4 DAY(0.104)GT(0.111)S(0.11)S(0.688)LS(0.713)S(0.117)S(0.124)S(0.124)NS(0.673)GS(0.63)Y(0.604)K 42.647 0.038655 1425600.0 3850.7 3643.1 4018.5 4094.0 4201.3 4527.4 2777.4 4166.1 3190.8 4362.5 True False 3795.788311868103 3634.6646257813986 3688.114441858583 4395.086417183643 3954.187794073605 4333.773655884871 2921.200182077428 4359.672215095787 2831.4185033864196 5116.552312334139 0.7418644587523993 0.7103737837331496 0.7208202353307102 0.8589937420533539 0.772822704175525 0.8470105241448866 0.5709313623229223 0.852072244934584 0.5533840622641351 1.0 12.32095629072237 DAYSGGAVNLYHVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DAYSGGAVNLYHVR 14 0 P28074;P28074-3 P28074 PSMB5 Proteasome subunit beta type-5 0 151.99 0.00020887 3106400.0 18711.0 18850.0 17576.0 20734.0 21942.0 21812.0 28248.0 25736.0 25422.0 18184.0 False True 21878.40274090459 20721.303424689937 17995.07849735118 19572.341200534953 17642.62261196494 20668.140322168507 25572.14494219038 25060.45726954602 25793.748656301097 21480.615255535213 1.0185184400277767 0.9646512997038289 0.8377357111647039 0.9111629703200178 0.8213276203724527 0.9621763658209304 1.1904754420663461 1.16665453812308 1.2007918930373496 1.0 14.390747695656646 -7.1602856734569045 4.519290044152564 1.1528731831537276 0.9085026182587472 0.6770941064898953 0.07474147497467365 0.1267846350308572 4.312557601642408 0.029491093647539712 0.022500624980447134 6.913760428327523e-08 7.1602856734569045 -0.24437056489498032 DCDLQEDACYNCGR ddPTM_PC-9_AZD4547_30min_R2 2 DCDLQEDACYNCGR 14 0 P62633-2;P62633;P62633-7;P62633-3 P62633-2 CNBP Cellular nucleic acid-binding protein 0 ; 187.78 1.8868e-05 8283800.0 34063.0 32691.0 30164.0 30423.0 36081.0 36340.0 30107.0 27407.0 33414.0 24948.0 False True 44894.325445585644 43257.72644265209 29764.005651192507 23409.447380664496 31071.77595339467 34067.65405526459 32786.46467501275 23171.877900206273 35180.19582396699 24074.578113580206 1.8648021674058433 1.7968217859755924 1.2363251190018967 0.9723720710793883 1.290646748067723 1.4150883099399942 1.3618707883615315 0.9625040069605735 1.461300615860937 1.0 14.555222895841291 -5.252070176919121 5.162840195365971 1.2162831745944742 1.8422337273952212 0.6732155112165672 0.17256136726071936 0.09652552387385935 8.493134458805658 0.044701909544413256 0.11252797734800184 5.596671585077511e-06 5.252070176919121 0.625950552800747 DCDLQEDACYNCGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DCDLQEDACYNCGR 14 0 P62633-2;P62633;P62633-7;P62633-3 P62633-2 CNBP Cellular nucleic acid-binding protein 0 104.59 0.006695399999999999 0.0 7822.1 15260.0 9311.0 11704.0 10845.0 16158.0 12256.0 6767.4 11418.0 14671.0 False True 9146.2270364828 16774.911950173388 9533.00955216414 11048.262824879968 8720.000101483902 15310.64603546667 11095.022954244025 6589.762920653 11584.966649266225 17330.7361644279 0.527746020117474 0.9679284129086584 0.550063740034948 0.6374952985296155 0.503152319598638 0.8834388735830186 0.6401934025755379 0.38023560327337846 0.6684636208959709 1.0 14.081045317268092 DCDLQEDACYNCGR ddPTM_PC-9_Lapatinib_30min_R1 2 DCDLQEDACYNCGR 14 0 P62633-2;P62633;P62633-7;P62633-3 P62633-2 CNBP Cellular nucleic acid-binding protein 0 ; 236.08 3.1728e-26 13718300.0 59761.0 58744.0 41605.0 45722.0 47863.0 44381.0 48027.0 50480.0 46749.0 40665.0 False True 58908.79718117484 58607.981877220605 38184.39749994435 49084.54840412079 45047.792442278536 42482.92808716403 50513.60306208422 52825.48508630022 41483.63533120587 47693.891067293465 1.2351434505114662 1.2288362422459504 0.8006140125172061 1.0291579761203626 0.9445191288485683 0.8907415003574136 1.059121030632881 1.1075943669969464 0.8697892833418589 1.0 15.541516868184223 -5.232996674633554 23.840791813158045 0.9691337936379636 1.2319900984072767 0.6008432840038492 0.0876721374151423 274.64348525932917 230205.4320088269 0.0221608483292452 0.05859950700517495 5.847945618637464e-06 5.232996674633554 0.2628563047693131 DCDLQEDEACYNCGR ddPTM_PC-9_Lapatinib_30min_R1 1 DCDLQEDEACYNCGR 15 0 P62633-8;P62633-4 P62633-8 CNBP Cellular nucleic acid-binding protein 0 212.1 5.967399999999999e-63 0.0 4749.5 6913.4 4865.1 4319.2 4737.1 4613.5 5180.6 4519.5 5192.3 3486.4 False True 4681.7712590483725 6897.392447058028 4465.110257829088 4636.848376428819 4458.473091496932 4416.191359593773 5448.826119129519 4729.492469245919 4607.488496657045 4089.019594664009 1.144961805797624 1.686808362586186 1.0919757546908948 1.1339755824304933 1.0903525865503416 1.08001227613502 1.332550747920112 1.1566323808811527 1.1267954065736479 1.0 11.997539260966537 -5.300610759064628 24.99927055176639 1.1368002413168161 1.4158854554059639 0.38601688419916336 0.1455075145457601 448.94531152885907 286517.21128261904 0.03570580346874997 0.07432946490968852 5.004828970115446e-06 5.300610759064628 0.27908521408914777 DCDPGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 DCDPGSPR 8 0 Q00341;A0A024R4E5;Q00341-2;H0Y394 Q00341 HDLBP Vigilin 1 DCDPGS(1)PR 75.652 0.026068 202900000.0 454090.0 385340.0 478880.0 636540.0 581190.0 534250.0 442270.0 487190.0 424010.0 529850.0 True False 598481.1743412497 509893.61926559487 472529.7383053665 489795.5374449655 500501.80056964664 500843.2630441699 481631.1732094835 411905.9800124604 446422.3029664284 511300.1127737889 1.1705085905311188 0.9972491820888444 0.9241729592858992 0.9579413835601137 0.9788806770537136 0.979548508853458 0.9419735321329146 0.8056051029949551 0.8731120760850214 1.0 18.963810818666573 -1.5228818895435254 0.9509360491656035 0.924529412209612 176.64589726988316 0.6308664997464263 0.05466586918137732 821.7557753570378 1.4035947934292423 0.019123351888144378 314140.5072362626 0.0299997828027799 1.5228818895435254 175.72136785767356 DCDPGS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 DCDPGSPR 8 0 Q00341;A0A024R4E5;Q00341-2;H0Y394 Q00341 HDLBP Vigilin 1 DCDPGS(1)PR;DCDPGS(1)PR;DCDPGS(1)PR;DCDPGS(1)PR;DCDPGS(1)PR 120.27 0.003423 444575600.0 822329.0 1026100.0 1014897.0 1008407.0 1269363.0 1096753.0 1046311.0 1053732.0 1098015.0 906620.0 True False 961533.0579619132 1127964.426741346 1039095.9934983042 951909.2250896043 1020640.4323485385 1039237.3419566883 947196.8474443561 1026072.6515213399 1114071.3921347028 1070983.029200031 0.8978041964681072 1.0532047623423848 0.9702263856360592 0.8888182157289937 0.952994029336678 0.9703583657464161 0.8844181668796967 0.9580662097771645 1.0402325356797264 1.0 20.03050418864396 -8.183913974987878 6.0778659391170455 1.0196042603943511 0.9478580998486128 0.2720999180837961 0.04796827472528174 0.29458932331976945 18.000731477460157 0.034191081031564846 0.012488246798201333 6.547658571854552e-09 8.183913974987878 -0.07174616054573835 DCDPGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 DCDPGSPR 8 0 Q00341;A0A024R4E5;Q00341-2;H0Y394 Q00341 HDLBP Vigilin 1 DCDPGS(1)PR;DCDPGS(1)PR 75.652 0.026068 483520000.0 314690.0 440371.0 502632.0 399987.0 508204.0 431747.0 455252.0 454273.0 500588.0 397982.0 True False 310202.46289292147 439351.34800581384 461307.5371756287 429403.3782975171 478312.4398875067 413282.1872614136 478822.72099485574 475380.1819851212 444206.50801466766 466772.65842231945 0.6645686230667376 0.9412533919420452 0.9882916851531905 0.9199411545416785 1.0247224880398766 0.8854035895296387 1.025815699259818 1.0184405050456362 0.9516549437922845 1.0 18.832360530953828 -4.759370970842427 3.9290248287289886 0.9752372852650969 0.6279186816481153 0.8173860323169413 0.04399042310518822 0.1008972217343947 2.834307983736251 0.010631884326591009 0.10409709303227481 1.7403196712822168e-05 4.759370970842427 -0.34731860361698164 DCDPGS(ph)PRR ddPTM_PC-9_AZD4547_30min_R2 2 DCDPGSPRR 9 1 Q00341;A0A024R4E5;Q00341-2;H0Y394 Q00341 HDLBP Vigilin 1 DCDPGS(1)PRR;DCDPGS(1)PRR 80.763 0.026757 108958000.0 60128.0 52342.0 70834.0 104335.0 87654.0 74649.0 66173.0 74409.0 59753.0 75188.0 True False 79247.4532599057 69260.52789640258 69894.69487788656 80282.17770968119 75484.75511817468 69981.18622926374 72062.26880591293 62910.798798717515 62911.421591832805 72555.69100544593 1.0922293229066966 0.9545843604632471 0.9633247772754361 1.1064904295881535 1.0403698741220575 0.9645168457428246 0.9931994004509451 0.8670691151435043 0.8670776987998193 1.0 16.14680115805001 -7.432591364386002 1.8952825663094344 0.9032998972341842 1.023098198235057 0.37893910705061506 0.0606580765485203 0.3556255464322899 2.4968709224285934 0.03542145112704055 0.01932294048842146 3.6932493971925935e-08 7.432591364386002 0.11979830100087285 DCDPGS(ph)PRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DCDPGSPRR 9 1 Q00341;A0A024R4E5;Q00341-2;H0Y394 Q00341 HDLBP Vigilin 1 DCDPGS(1)PRR;DCDPGS(1)PRR 77.062 0.026022000000000003 36403000.0 63014.0 51110.0 62285.0 67347.0 74755.0 65914.0 64995.0 69025.0 64876.0 54097.0 True False 73681.02561676879 56183.86302577734 63770.11061717786 63573.76593191997 60107.29438325759 62457.35380503466 58838.20307694928 67213.16688803275 65824.68876666632 63904.357868383624 1.1529890616931169 0.8791867237206688 0.9978992473176516 0.994826770074984 0.9405820884242918 0.9773567232092498 0.9207228589657608 1.0517775176845356 1.0300500773709014 1.0 15.963626696648666 -7.787218123181325 24.998404547033058 1.0306853574068278 0.9761746623813137 0.08570935425681325 0.06871671436727377 503.5011582800615 488252.6010622833 0.035119343442023936 0.01688031211115733 1.6322319580853364e-08 7.787218123181325 -0.05451069502551409 DCDPGS(ph)PRR ddPTM_PC-9_Lapatinib_30min_R1 1 DCDPGSPRR 9 1 Q00341;A0A024R4E5;Q00341-2;H0Y394 Q00341 HDLBP Vigilin 1 DCDPGS(1)PRR 79.65899999999999 0.02912 40991000.0 17382.0 18121.0 23103.0 18185.0 19046.0 20469.0 16639.0 16327.0 19413.0 16401.0 True False 17134.129492531592 18079.041937850914 21203.560520158993 19522.385563381667 17925.75172587672 19593.588585569516 17500.486004747727 17085.612024643902 17226.503512047315 19235.8909970412 0.8907375018483473 0.9398598661549794 1.1022915716989898 1.014893750769566 0.9318908975224489 1.018595322077014 0.9097829680694071 0.8882152652701117 0.8955396718923516 1.0 14.231513035658732 -7.276958558967834 23.76767538133933 0.9140690668859984 0.9856246727795552 0.1768690517543905 0.061607203180199535 684.2643984103472 1047947.2543439928 0.026769869702038287 0.018132809067393025 5.284956792211999e-08 7.276958558967834 0.0715556058935568 DCEYQQISPGAAPLPAS(ph)PGAR ddPTM_PC-9_Lapatinib_30min_R1 1 DCEYQQISPGAAPLPASPGAR 21 0 Q9NUE0 Q9NUE0 ZDHHC18 Palmitoyltransferase ZDHHC18 1 DCEYQQISPGAAPLPAS(1)PGAR 197.69 1.0376e-64 0.0 11157.0 20077.0 13599.0 7924.0 11046.0 5970.3 8710.2 8075.3 11388.0 5687.3 True False 10997.899134056785 20030.512940027194 12480.942713658058 8506.7573936891 10396.295997271558 5714.964186449052 9161.171536664084 8450.507918332018 10105.363519043673 6670.342227149103 1.6487758438081332 3.0029213281592324 1.8711098004625768 1.2753104869290761 1.558585098521238 0.8567722602280367 1.3734185180749803 1.2668777149000578 1.5149692736773859 1.0 12.703545066573456 -5.5939222462006954 3.83102817846764 1.2763760827190982 2.353226673657589 0.581498375075469 0.36556734927480133 0.1353584788207055 3.9290027485639096 0.09465874677519387 0.17751826655786415 2.547286264494874e-06 5.5939222462006954 1.076850590938491 DCGATWVVLGHSER ddPTM_PC-9_AZD4547_30min_R2 4 DCGATWVVLGHSER 14 0 P60174;P60174-3;P60174-4;U3KPZ0;U3KQF3;U3KPS5 P60174 TPI1 Triosephosphate isomerase 0 ;;; 153.14 1.6963e-05 120771800.0 176159.5 185071.0 265807.0 352248.0 281594.0 267848.0 217693.0 297868.0 235428.0 259602.0 False True 232174.55665477668 244891.5814893413 262282.2255047913 271042.66577734926 242499.53376625443 251099.4222177904 237067.25527277842 251839.34492569906 247872.2434442124 250513.41299669884 0.9267949124058925 0.9775587604667235 1.0469787719839478 1.0819487169771662 0.968010179037599 1.0023392329140446 0.9463255976473499 1.0052928580275966 0.9894569734973782 1.0 17.934528324746594 DCGATWVVLGHSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DCGATWVVLGHSER 14 0 P60174;P60174-3;P60174-4;U3KPZ0;U3KQF3;U3KPS5 P60174 TPI1 Triosephosphate isomerase 0 ;;; 156.24 4.4285e-05 92266600.0 205428.0 226901.0 223989.0 272223.0 280943.0 252396.0 262748.0 215014.0 230078.0 183888.0 False True 240202.9030120544 249426.23174353203 229329.7472430126 256971.22786887392 225894.23591620036 239159.9094422359 237858.60730921233 209370.11032616408 233442.45548518788 217225.4387433926 1.1057770415913626 1.1482367497398778 1.055722334224026 1.1829702329312952 1.0399069152441587 1.100975607763667 1.0949850472632425 0.9638378982559774 1.074655237598357 1.0 17.72883353798383 -7.409499679097639 0.947418654780026 1.0103870609179892 1.115364118820762 0.39349063174568544 0.04838437652205812 0.5628589960767755 0.9513795275048134 0.0366227903567883 0.018791114544119084 3.8949359550231066e-08 7.409499679097639 0.10497705790277267 DCGATWVVLGHSER ddPTM_PC-9_Lapatinib_30min_R1 5 DCGATWVVLGHSER 14 0 P60174;P60174-3;P60174-4;U3KPZ0;U3KQF3;U3KPS5 P60174 TPI1 Triosephosphate isomerase 0 ;;;; 150.9 8.4329e-06 148118900.0 302900.0 309690.2 321281.1 279020.2 337731.0 319945.6 271935.2 302013.0 298007.4 273450.2 False True 298580.5904549428 308973.1313692098 294866.60813891084 299540.27629210206 317866.3265846935 306262.27251762146 286014.67406684754 316045.6265326625 264442.66845495754 320715.7027205119 0.9309821375199119 0.9633863535471003 0.9194018429333743 0.933974463212164 0.991115570233549 0.9549338243176516 0.8918012795778054 0.9854385795636607 0.8245391984607827 1.0 18.29093546645276 -10.015073218203527 5.823660070183236 0.9999999992755361 0.9360815195088015 0.15707198981652992 0.04612690487198356 29109102.620001912 6.428411784011847 0.06034305803251187 0.010504377938971538 9.658880250952315e-11 10.015073218203527 -0.06391847976673459 DCIHEHLS(ph)GDEFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DCIHEHLSGDEFEK 14 0 A0AVK6;E9PMT9 A0AVK6 E2F8 Transcription factor E2F8 1 DCIHEHLS(1)GDEFEK 57.173 0.038610000000000005 6084100.0 28939.0 22085.0 27285.0 31098.0 30750.0 25529.0 36914.0 40339.0 30475.0 23556.0 True False 33837.80112869637 24277.45284531974 27935.577878938737 29355.679881076307 24724.758240721985 24190.214298763993 33417.23868578363 39280.14399270348 30920.639221964277 27826.5163308066 1.2160272139863482 0.8724574990525239 1.0039193389080974 1.0549534671207397 0.8885322886555269 0.8693224121620687 1.200913484408667 1.4116083927191643 1.111193325616983 1.0 14.764172685026125 -7.319862718240146 8.995299569427125 1.2158824059472153 0.9789774098492512 0.31595006063731845 0.1379176242890084 0.44814842746283046 66.04576401276934 0.05604955411580681 0.03776687841392295 4.7878141261415076e-08 7.319862718240146 -0.23690499609796412 DCIHEHLS(ph)GDEFEK ddPTM_PC-9_Lapatinib_30min_R1 2 DCIHEHLSGDEFEK 14 0 A0AVK6;E9PMT9 A0AVK6 E2F8 Transcription factor E2F8 1 DCIHEHLS(1)GDEFEK;DCIHEHLS(1)GDEFEK 78.848 0.0076325 14799800.0 50618.0 49498.0 52286.0 55076.0 57949.0 55289.0 40949.0 46082.0 48010.0 41877.0 True False 49896.17803779563 49383.39042214805 47987.24690979668 59126.47276815004 54540.55375211747 52924.41835495395 43069.13885500418 48223.13795061184 42602.608232287166 49115.38365240503 1.0158971451982615 1.0054566767031636 0.9770308881104891 1.203827973463357 1.1104576549397835 1.0775527832482361 0.8768971277880921 0.9818336815180411 0.8673984618300146 1.0 15.583887347937553 -7.250244739318853 24.807059757829986 0.9300184580713241 1.066701940989111 0.4632468985849255 0.07038056340717783 625.6467676099244 1386420.8470561062 0.028622310105897848 0.02195145707043154 5.620245165104979e-08 7.250244739318853 0.13668348291778687 DCIIVGGMDMVAQALELS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 DCIIVGGMDMVAQALELSR 19 0 Q9Y6V7 Q9Y6V7 DDX49 Probable ATP-dependent RNA helicase DDX49 1 DCIIVGGMDMVAQALELS(1)R 71.781 0.0053449 13699000.0 1920.2 4805.3 75125.0 118650.0 75668.0 61061.0 18729.0 92392.0 41103.0 49999.0 True False 2530.783657358821 6358.519252236885 74128.79341419703 91297.07562422635 65162.80432475457 57242.8460172953 20395.844717119406 78114.93935694746 43275.62066656238 48248.550228511165 0.052453050824796045 0.131786742236236 1.5363942141911788 1.8922242262582396 1.35056502249571 1.1864158766675066 0.42272450924477806 1.6190111202717044 0.8969310054209636 1.0 15.558197972509216 -5.251261232771256 24.030091631328954 1.2565620910083357 0.09211949124019223 0.5797318312947627 0.3900114706003071 293.7073335500848 693421.5986096677 0.10460279862516492 0.2694774022400346 5.607106011576162e-06 5.251261232771256 -1.1644425997681436 DCIIVGGMDMVAQALELS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DCIIVGGMDMVAQALELSR 19 0 Q9Y6V7 Q9Y6V7 DDX49 Probable ATP-dependent RNA helicase DDX49 1 DCIIVGGMDMVAQALELS(1)R;DCIIVGGMDMVAQALELS(1)R 75.479 0.0035444 16178500.0 5506.299999999999 5431.7 88209.0 32632.9 57641.0 58374.0 17438.0 29876.2 42827.0 17774.1 True False 6438.407835617706 5970.923279145272 90312.23709449534 30804.584410289277 46346.65982938065 55312.76467844601 15786.146399812927 29091.981406450526 43453.26385427614 20996.40363030182 0.3066433637390098 0.28437838137804183 4.3013193442403415 1.467136227360022 2.207361824693329 2.6343923298663934 0.7518500157346235 1.3855697346409004 2.0695574641918575 1.0 14.357854616533391 -7.270886797454534 24.727545787096645 1.3338752046419542 1.9029041152844852 0.05595003889749284 1.1283554380491643 2153.6823448935647 5636994.954006027 0.4871354841081001 0.33341035632313304 5.359363356663644e-08 7.270886797454534 0.569028910642531 DCLCQLCAQPMSS(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 1 DCLCQLCAQPMSSSPK 16 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;A0A494C1P1;A0A494C1G0 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 DCLCQLCAQPMSS(0.5)S(0.5)PK 160.03 4.7742e-05 4834800.0 21904.0 21636.0 16801.0 14360.0 18678.0 17709.0 23599.0 22096.0 19864.0 19661.0 True False 28869.016368496843 28629.413884959802 16578.207762421614 11049.52385978838 16084.882105748346 16601.65343050856 25699.26528267931 18681.57091556747 20913.97048684026 18972.67437434265 1.5216102800740274 1.5089814603931784 0.8737939330704401 0.582391477436149 0.8477920291248157 0.8750296928597217 1.3545409980489225 0.9846566987325284 1.102320636205241 1.0 14.211635433873788 -5.256453736916698 24.4067518012466 0.9466423979795002 1.5152959830735648 0.5927760952647938 0.1865138802071423 216.92986162293144 1061946.6307965487 0.05330509887555494 0.13193142803872995 5.540465604310428e-06 5.256453736916698 0.5686535850940646 DCLCQLCAQPMSS(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 1 DCLCQLCAQPMSSSPK 16 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;A0A494C1P1;A0A494C1G0 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 DCLCQLCAQPMS(0.003)S(0.714)S(0.283)PK 167.92 3.6809e-05 4418400.0 21851.0 31581.0 22349.0 29525.0 30754.0 28081.0 27537.0 27343.0 26500.0 24158.0 True False 21539.40073301736 31507.87613483087 20511.551489634818 31696.36699251272 28945.11018469037 26880.041090008173 28962.731120424196 28613.45560052905 23515.290942628828 28333.67811148839 0.7602048928580095 1.1120291552283657 0.7239283021754259 1.1186816927824443 1.0215796929292447 0.9486957882502797 1.022201600740313 1.0098743794554235 0.8299413457758645 1.0 14.790230275609508 -4.734625749450377 24.373123676706804 0.9751799011523127 0.7602033995604707 0.24369317699038884 0.11420474587535963 2937.5613053434527 2669998.89043817 0.02677475368007512 2.179058668183417 1.842358958888846e-05 4.734625749450377 -0.214976501591842 DCLCQLCAQPMSSS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DCLCQLCAQPMSSSPK 16 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;A0A494C1P1;A0A494C1G0 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 DCLCQLCAQPMS(0.002)S(0.286)S(0.712)PK;DCLCQLCAQPMS(0.019)S(0.188)S(0.794)PK 110.56 0.0034631 0.0 28778.0 29460.0 24616.0 27853.0 25806.0 24088.0 31982.0 24145.0 22972.0 22675.0 True False 33649.54700859133 32384.594105642747 25202.938796699862 26292.486710644367 20749.499549921024 22824.782875499495 28952.43343037144 23511.21933374217 23307.92204124574 26785.798004798777 1.256245828575385 1.2090210678002173 0.9409067742609222 0.9815831025804782 0.7746455620326739 0.8521225640322663 1.080887469739916 0.8777494450428561 0.8701597031781557 1.0 14.709180657142046 -5.244490583856785 2.8554228456408195 0.913677186557137 1.256349877294378 0.6998932742656623 0.08157312613881813 0.14863585563755913 2.3864770237931916 0.02270437530199426 0.07129546018710897 5.695205720378364e-06 5.244490583856785 0.34267269073724094 DCLCQLCAQPMSSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 DCLCQLCAQPMSSSPK 16 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;A0A494C1P1;A0A494C1G0 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 DCLCQLCAQPMS(0.031)S(0.226)S(0.743)PK 151.11 2.7334e-05 4820300.0 21183.0 26858.0 18022.0 25081.0 26437.0 21718.0 26379.0 24794.0 19994.0 21269.0 True False 20880.926535513565 26795.811951150616 16540.300726931797 26925.540407763285 24882.02763714179 20789.17176713072 27744.775546561727 25946.019754947054 17742.06517384608 24945.318310838928 0.8370679530050593 1.0741820014983587 0.6630623237926337 1.0793825146766693 0.9974628235683953 0.8333897169833936 1.1122237528036039 1.0401158017564087 0.711238275365563 1.0 14.606481458298026 DCLHGIEAK ddPTM_PC-9_Lapatinib_30min_R1 1 DCLHGIEAK 9 0 Q8N684-2;Q8N684;Q8N684-3;F5H669 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 0 85.807 0.0096906 0.0 25397.0 19590.0 20683.0 20307.0 26642.0 19143.0 19609.0 21699.0 22321.0 23415.0 False True 25034.834122760607 19544.640558606014 18982.523578688833 21800.444522166148 25074.9699401873 18324.29851451254 20624.258072426113 22707.214756094076 19806.973929449734 27462.251551473688 0.9116089434923692 0.7116911197893824 0.6912224055303356 0.7938331087421813 0.9130704339077296 0.6672540479853414 0.7510039019841172 0.8268518957206753 0.7212436275417791 1.0 14.745162292324421 -10.741994241478839 4.573682321966167 1.0000391460708982 0.7740666285137048 0.4018139677234501 0.08179358194639551 4.990476444038671e-05 8.520502117070415e-06 0.07820576027516588 0.01896260493958452 1.8113641102155908e-11 10.741994241478839 -0.2259725175571934 DCRS(ph)PGLLDTTPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DCRSPGLLDTTPIR 14 1 Q8IY92;Q8IY92-2 Q8IY92 SLX4 Structure-specific endonuclease subunit SLX4 1 DCRS(1)PGLLDTTPIR 59.607 0.027813 2779200.0 7424.4 5609.3 7130.5 8263.4 10083.0 8701.0 7418.2 9190.7 7691.0 6129.2 True False 8681.204281415858 6166.154233427757 7300.518162571843 7800.428488304267 8107.308531421132 8244.704242764916 6715.494392882915 8949.453863351595 7803.4663250574995 7240.375441279497 1.1989991888986549 0.8516345987077838 1.008306574953207 1.0773513820611766 1.1197359304324188 1.1387122545827453 0.927506376892546 1.2360483148882229 1.0777709510155589 1.0 12.821848793189986 -5.783406441346479 4.980440706782679 1.090426859283728 1.002119422999639 0.055366125890992324 0.10987779275305608 0.4041302787054388 25.82408179774779 0.029781225231000245 0.047514292166512054 1.6466206542763002e-06 5.783406441346479 -0.08830743628408899 DCS(ph)PTCWEQGK ddPTM_PC-9_Lapatinib_30min_R1 1 DCSPTCWEQGK 11 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 DCS(0.944)PT(0.056)CWEQGK 145.14 0.00019553 7423200.0 24934.0 31812.0 34902.0 31504.0 38831.0 35259.0 33405.0 31634.0 42012.0 29497.0 True False 24578.43658766442 31738.34126852346 32032.4922856161 33820.90925426316 36547.03692468332 33751.05476274342 35134.5474480797 33103.831125594705 37280.16615402728 34595.51714771808 0.7104514866107621 0.9174119621627603 0.9259145382577108 0.9776095876772865 1.056409614246624 0.9755904101283146 1.0155809291146027 0.9568821007717827 1.0776010659082251 1.0 15.078297486551422 -4.070201106074755 0.8882195509116925 1.0086707026904245 9.458307266764272e-13 0.8457408621537332 0.03800003076592441 2.393266806928971 0.5964292913364247 0.012394588240260414 3.171659338291036 8.507439981855444e-05 4.070201106074755 -1.0086707026894786 DCSPT(ph)CWEQGK ddPTM_PC-9_AZD4547_30min_R2 1 DCSPTCWEQGK 11 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 DCS(0.16)PT(0.84)CWEQGK 125.82 0.0010806 4006000.0 15927.0 15880.0 21604.0 21721.0 23635.0 19272.0 19363.0 20784.0 19614.0 18397.0 True False 20991.454697819994 21012.899449674696 21317.51684419717 16713.559036104696 20353.688219796648 18066.91879342485 21086.269488898673 17572.31036880677 20650.755997225388 17752.926629610993 1.1824222076605273 1.183630163526178 1.200788877741466 0.9414537323793879 1.1464976251210162 1.01768678316341 1.1877630054375279 0.9898261134869468 1.1632310789129812 1.0 14.115769256898174 -5.682024614363845 24.999999999987075 1.0700374124121352 1.1884173553068345 0.35523373064807584 0.07695206516032942 34.490122489205795 10855.397219498545 0.01914024853357937 0.03315187840827342 2.0795788201667353e-06 5.682024614363845 0.11837994289469922 DCSYGAVT(ph)SPTSTLESR ddPTM_PC-9_AZD4547_30min_R2 1 DCSYGAVTSPTSTLESR 17 0 Q9HCD6;Q9HCD6-2;Q9HCD6-3;Q9HCD6-4;J3KRP9 Q9HCD6 TANC2 Protein TANC2 1 DCSYGAVT(0.459)S(0.459)PT(0.06)S(0.018)T(0.003)LESR 149.6 0.00014923 76577000.0 30733.0 30983.0 42796.0 64036.0 53098.0 54887.0 45349.0 61372.0 44999.0 42601.0 True False 40505.45471388846 40997.64884441251 42228.49707759037 49273.48954633769 45726.25923819602 51454.907213299615 49384.97314734625 51888.36758826063 47377.55527272077 41109.55195673521 0.9853051854351874 0.9972779291673997 1.0272186162970778 1.1985897972859063 1.1123025443410222 1.251653320558009 1.2013016634022262 1.2621973511866376 1.1524707280337712 1.0 15.327186027945617 -5.694816502612494 4.431591561735712 1.18210781024832 0.9963135710217087 0.5238593367975004 0.07159391900905861 0.14572813803780754 5.559435450213143 0.01897177477665791 0.033285217581691534 2.0192193406919005e-06 5.694816502612494 -0.1857942392266113 DCSYGAVT(ph)SPTSTLESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DCSYGAVTSPTSTLESR 17 0 Q9HCD6;Q9HCD6-2;Q9HCD6-3;Q9HCD6-4;J3KRP9 Q9HCD6 TANC2 Protein TANC2 1 DCSYGAVT(0.395)S(0.395)PT(0.151)S(0.045)T(0.013)LESR;DCS(0.079)Y(0.015)GAVT(0.29)S(0.29)PT(0.12)S(0.158)T(0.049)LESR;DCS(0.005)Y(0.06)GAVT(0.455)S(0.455)PT(0.017)S(0.007)T(0.002)LESR 185.86 7.3907e-08 68085100.0 63624.0 70678.0 99755.0 98547.0 114323.0 99406.0 112940.0 102739.0 100018.0 82887.0 True False 74394.28656871966 77694.4447453705 102133.5375229444 93025.73108368464 91922.22882452235 94192.97436573818 102241.5055852089 100042.21011096859 101480.57403453387 97913.75696686914 0.7597940153996163 0.7934987600532967 1.0430969118823936 0.9500782521822909 0.9388081069713816 0.9619993888867939 1.0441995972006684 1.0217380397814746 1.0364281504270296 1.0 16.579223953510663 -5.218961855755547 6.925160769930173 0.9966076390680614 0.7740258295389303 0.851188130400663 0.037271530438960115 0.08996748896169868 11.852564102873504 0.01046863185926094 0.02772989407126577 6.040016767367013e-06 5.218961855755547 -0.2225818095291311 DCSYGAVT(ph)SPTSTLESR ddPTM_PC-9_Lapatinib_30min_R1 3 DCSYGAVTSPTSTLESR 17 0 Q9HCD6;Q9HCD6-2;Q9HCD6-3;Q9HCD6-4;J3KRP9 Q9HCD6 TANC2 Protein TANC2 1 DCS(0.001)Y(0.001)GAVT(0.461)S(0.461)PT(0.021)S(0.028)T(0.028)LESR;DCSYGAVT(0.587)S(0.404)PT(0.009)STLESR;DCSYGAVT(0.519)S(0.415)PT(0.031)S(0.027)T(0.006)LES(0.001)R 128.82 2.656e-05 3102400.0 36774.0 38880.0 46905.0 42052.0 44872.0 45350.0 42450.0 42516.0 51426.0 34448.0 True False 36249.596016474345 38789.975748780096 43048.65195853599 45144.64436135969 42232.71718174631 43410.48621601338 44647.8532905548 44491.44857228882 45633.862340212494 40402.29090092526 0.897216351057068 0.9600934720236807 1.065500272350896 1.1173783306511915 1.045305012166504 1.0744560580107902 1.1050822192246605 1.1012110348245108 1.1294869999356254 1.0 15.302149478905227 -5.143839624440748 2.3526585532621644 1.0860451371410287 0.898716695965964 0.7498395025030842 0.03582323988933864 0.15221988895605773 1.5135102424471882 0.009437235722557811 0.0417230485520507 7.180594061262621e-06 5.143839624440748 -0.18732844117506464 DCSYGAVTS(ph)PTSTLESR ddPTM_PC-9_AZD4547_30min_R2 1 DCSYGAVTSPTSTLESR 17 0 Q9HCD6;Q9HCD6-2;Q9HCD6-3;Q9HCD6-4;J3KRP9 Q9HCD6 TANC2 Protein TANC2 1 DCS(0.001)YGAVT(0.325)S(0.657)PT(0.013)S(0.004)TLESR 222.09 2.613e-23 76251000.0 24461.0 20345.0 31159.0 47422.0 34111.0 36108.0 29921.0 36769.0 28442.0 33349.0 True False 32239.089179592807 26921.123381840767 30745.811301071077 36489.59056259644 29375.276448719433 33850.16105193987 32583.91103534249 31087.195917564302 29945.386054506165 32181.461660645607 1.00179070545505 0.8365413499773487 0.9553889013894551 1.1338698952639308 0.9128011884134576 1.0518528154156186 1.0125056275858668 0.9659970154674649 0.9305166549077565 1.0 14.973942233350883 -5.524722259439672 24.99959384510061 1.0021171136167004 0.913365785416956 0.18678531321169578 0.06933572018429406 79.94981471541837 1084181.7320549344 0.01806841302203943 0.0315736417320795 2.9872924452357697e-06 5.524722259439672 -0.0887513281997444 DCSYGAVTS(ph)PTSTLESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DCSYGAVTSPTSTLESR 17 0 Q9HCD6;Q9HCD6-2;Q9HCD6-3;Q9HCD6-4;J3KRP9 Q9HCD6 TANC2 Protein TANC2 1 DCSYGAVT(0.192)S(0.592)PT(0.186)S(0.029)T(0.001)LESR 127.2 4.8385e-05 0.0 6367.3 7137.6 9041.0 9919.0 12255.0 11518.0 11658.0 11411.0 10220.0 8306.4 True False 7445.15813009255 7846.173757244925 9256.571728183435 9363.27058783189 9853.720723253597 10913.975803719832 10553.669843389103 11111.473340953891 10369.448165659554 9812.284566573782 0.7587588883688707 0.7996276202560871 0.9433656010870882 0.9542396089620669 1.004222885750885 1.112276731241472 1.075556846296621 1.1324043106949715 1.0567822503827282 1.0 13.26037335883804 -5.420596831267889 0.7748583442231914 1.08460068125133 0.6904303795864286 0.8822210793096883 0.040619243703012134 0.38370732360942844 0.3166838955062698 0.017669413283984546 0.11270119593737132 3.796672780691054e-06 5.420596831267889 -0.3941703016649014 DCSYGAVTS(ph)PTSTLESR ddPTM_PC-9_Lapatinib_30min_R1 1 DCSYGAVTSPTSTLESR 17 0 Q9HCD6;Q9HCD6-2;Q9HCD6-3;Q9HCD6-4;J3KRP9 Q9HCD6 TANC2 Protein TANC2 1 DCSYGAVT(0.035)S(0.773)PT(0.085)S(0.085)T(0.023)LESR 199.05 2.0877e-12 68247000.0 27504.0 23395.0 22875.0 18753.0 24557.0 24822.0 20578.0 22910.0 24291.0 22344.0 True False 27111.787916384143 23340.83031488453 20994.30580005353 20132.158178174115 23112.605540919587 23760.420922908135 21643.428151072694 23974.48223706691 21555.09178443007 26206.130628491483 1.0345589854805968 0.8906629767581262 0.8011219243953696 0.7682232246940834 0.8819541453323676 0.9066741389541745 0.8258917906614498 0.9148425067759408 0.8225209623657768 1.0 14.677616733017944 -11.168010534243217 5.642494895156545 1.0013080086651993 0.8684918433482558 0.2257060359539167 0.07097742484697182 0.0012074629673639683 7.593980605652084e-05 0.07105192765442112 0.017067810886406062 6.791871580595182e-12 11.168010534243217 -0.1328161653169435 DCSYGAVTSPT(ph)STLESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DCSYGAVTSPTSTLESR 17 0 Q9HCD6;Q9HCD6-2;Q9HCD6-3;Q9HCD6-4;J3KRP9 Q9HCD6 TANC2 Protein TANC2 1 DCSYGAVT(0.365)S(0.12)PT(0.428)S(0.084)T(0.003)LESR 143.43 0.00028948 48255000.0 34123.0 41173.0 43920.0 53419.0 65305.0 62535.0 58176.0 54608.0 51945.0 39555.0 True False 39899.34994002926 45260.38333712249 44967.21936752753 50426.10661673471 52508.954045864986 59255.55451342421 52665.14812223406 53174.59786195864 52704.597354714875 46726.00838279227 0.8539002435894554 0.968633634748704 0.9623595278916987 1.0791871243019566 1.123762886307284 1.2681492933868106 1.1271056515417865 1.1380085674414504 1.1279499186608102 1.0 15.511938178311876 -5.721969401746065 1.5397529883619048 1.1449386220094906 0.9016781736688532 0.6606369743465305 0.06556807967122741 0.23308248267319817 1.1102321058913944 0.020864931185874618 0.04940796699637078 1.896839558492633e-06 5.721969401746065 -0.24326044834063743 DCVGPEVEK ddPTM_PC-9_Lapatinib_30min_R1 1 DCVGPEVEK 9 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 89.24700000000001 0.043739 23419000.0 136660.0 125780.0 134250.0 117730.0 132650.0 111020.0 133810.0 103930.0 109680.0 121360.0 False True 134711.20333962524 125488.76413790022 123212.48321998658 126388.25693576696 124847.78779993425 106271.93340026039 140738.02706264151 108758.96721511838 97326.68341839749 142336.914297965 0.9464249243005488 0.8816318996153364 0.8656396959825632 0.8879513621546448 0.8771286662754301 0.7466224339934265 0.988766882834228 0.7640952998843625 0.6837768255580975 1.0 17.11895033987239 -3.70044949821753 0.49212749953827895 0.832715839423088 1.196973109525541 0.08402060896281371 0.09481964457682499 30.34012887269458 2.4968442390474124 0.05537810833607836 8.044102931885346 0.00019931982710553965 3.70044949821753 0.3642572701024529 DDAT(ph)PVRDEPMDAESITFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DDATPVRDEPMDAESITFK 19 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;H3BSK8 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 DDAT(0.998)PVRDEPMDAES(0.002)ITFK 52.731 0.028118999999999998 8524800.0 32372.0 52478.0 35672.0 31476.0 36571.0 28845.0 35513.0 24713.0 28426.0 25959.0 True False 37851.94022385564 57687.66902498033 36522.55576681334 29712.501766568857 29405.175077120133 27332.317421279604 32148.951548145225 24064.30993558792 28841.67647329145 30665.16120866906 1.2343629947445012 1.8812119927376085 1.1910113734046959 0.9689334931058219 0.9589114786328686 0.8913149758219024 1.0483868429511696 0.7847442826677502 0.9405356220706217 1.0 14.904312914885988 -5.512821422221585 4.15101452723336 0.9403752007906063 1.5619341192626566 0.6990713665384298 0.16028465686721824 0.09722720760123521 3.922692759281131 0.04056823664734023 0.08170985280635541 3.070284200657815e-06 5.512821422221585 0.6215589184720502 DDAT(ph)PVRDEPMDAESITFK ddPTM_PC-9_Lapatinib_30min_R1 3 DDATPVRDEPMDAESITFK 19 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;H3BSK8 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 DDAT(1)PVRDEPMDAESITFK;DDAT(1)PVRDEPMDAESITFK;DDAT(1)PVRDEPMDAESITFK 85.176 0.00094455 11401700.0 45408.0 68894.0 57413.0 58858.0 66047.0 65030.0 70257.0 75245.0 61320.0 64568.0 True False 44760.47359319267 68734.48017583459 52692.724760589 63186.613664532226 62162.24531339802 62248.818492334016 73894.56368985883 78741.15739537773 54413.495871773564 75728.49276854817 0.591065158658258 0.9076435785657369 0.6958110855531715 0.834383616450044 0.8208567613168642 0.8219999661499591 0.9757828393033723 1.0397824453741247 0.7185339874395701 1.0 16.20854859444737 -2.619894308562075 0.20732942144484567 0.9810529930686646 6.025182057150479e-12 0.3702617411810064 0.10844730023554577 37.458989673538184 0.6857959238551175 0.18978629398031455 10.990074436779228 0.0023994167785073312 2.619894308562075 -0.9810529930626394 DDDVPLDWR ddPTM_PC-9_AZD4547_30min_R2 2 DDDVPLDWR 9 0 O95340;O95340-2 O95340 PAPSS2 Bifunctional 3-phosphoadenosine 5-phosphosulfate synthase 2;Sulfate adenylyltransferase;Adenylyl-sulfate kinase 0 ; 141.52 0.0032863 4189400.0 27530.0 30006.0 37907.0 40137.0 33885.0 43228.0 32329.0 44344.0 34078.0 34606.0 False True 36283.967340427225 39704.85270068885 37404.3284120062 30884.034760468414 29180.65264767548 40524.94632638906 35206.2183704284 37491.6537237475 35879.29350838412 33394.45447324661 1.086526727648613 1.1889654533059584 1.1200760426247427 0.92482525160609 0.8738173181134927 1.2135232320939668 1.0542534359599514 1.1226910070887155 1.0744087326573397 1.0 15.027320926314749 -1.524030132517654 0.00788629534992849 0.16060619798956385 2.0680318033397613 0.03556958529072274 0.10056932009057097 109794.41995379425 67.2486142837171 7234.889838156465 9132.500932536148 0.029920570324527353 1.524030132517654 1.9074256053501975 DDDVPLDWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DDDVPLDWR 9 0 O95340;O95340-2 O95340 PAPSS2 Bifunctional 3-phosphoadenosine 5-phosphosulfate synthase 2;Sulfate adenylyltransferase;Adenylyl-sulfate kinase 0 ;; 97.635 0.021748 2357020.0 29979.3 31492.8 37113.2 37287.0 39739.0 31920.5 38580.0 34387.0 33660.7 25908.9 False True 35054.20337183478 34619.19705533556 37998.11944059481 35197.930276085055 31952.42821879839 30246.532787171305 34925.423104988105 33484.37768603819 34152.92405771199 30605.978475260465 1.1453384311882047 1.1311253153797736 1.2415260460079585 1.150034471354555 1.0439930304671126 0.9882557034280179 1.1411307478118744 1.0940469592600808 1.1158906121991365 1.0 14.901525871492016 -6.152032404152938 5.18170410807702 1.0689669635912489 1.1722302742929223 0.48431406788222275 0.05222861905558706 0.21664641753242217 8.576174736565592 0.016183432025273545 0.0211157906852815 7.046404914395547e-07 6.152032404152938 0.10326331070167338 DDDVPLDWR ddPTM_PC-9_Lapatinib_30min_R1 2 DDDVPLDWR 9 0 O95340;O95340-2 O95340 PAPSS2 Bifunctional 3-phosphoadenosine 5-phosphosulfate synthase 2;Sulfate adenylyltransferase;Adenylyl-sulfate kinase 0 ; 116.05 0.00088257 2145100.0 21492.5 22069.4 28107.2 25514.2 27703.9 22370.6 24823.7 25247.2 24994.6 22506.7 False True 21186.013008758222 22018.299660239896 25796.334512929596 27390.59938087613 26074.41106996303 21413.861586415613 26108.949722703044 26420.27708143499 22179.4449431936 26396.953106707362 0.8025931221348019 0.8341227705801065 0.9772466696686615 1.0376424608609955 0.9877810883915092 0.8112247462747674 0.98908952170199 1.0008835858681622 0.8402274631293675 1.0 14.688083794302695 -5.189724392490992 4.954108993058826 0.9556223805848622 0.8123960412066227 0.38783729058537886 0.06915739471320893 0.22491921815746654 10.379220693077993 0.018162579596402727 0.05085834376522468 6.460640975377262e-06 5.189724392490992 -0.14322633937823948 DDEVQVVR ddPTM_PC-9_Lapatinib_30min_R1 1 DDEVQVVR 8 0 J3QRI7;J3QQQ9;J3QQV1;E5RIT6;J3QRC4;Q9UNX3;P61254 J3QRI7 RPL26;RPL26L1 60S ribosomal protein L26-like 1;60S ribosomal protein L26 0 89.698 0.046213 4904900.0 30307.0 26408.0 27199.0 23493.0 29316.0 29203.0 24955.0 25502.0 31157.0 22067.0 False True 29874.8166223769 26346.853898502683 24962.803211176215 25220.753590350607 27591.690517473584 27954.05576551793 26247.04779424722 26686.916019628152 27647.770562244765 25881.25154757077 1.1543033986384237 1.017989947281959 0.9645129859849935 0.9744796747558309 1.066087954315461 1.080089025607485 1.0141336382440433 1.0311292701814105 1.0682547755245555 1.0 14.65961976341063 -4.759725911365267 24.991410339762048 1.0243895046900544 1.154303560887609 0.5282892877084437 0.036916065726629935 38.877896589013254 566877.9965828006 0.010068192890975058 0.062375545825027835 1.7388979225672845e-05 4.759725911365267 0.1299140561975547 DDFFYEDR ddPTM_PC-9_AZD4547_30min_R2 2 DDFFYEDR 8 0 G3V1T9;J3KPD3;Q9Y580 G3V1T9 RBM7 RNA-binding protein 7 0 ; 100.19 0.019117 0.0 9689.0 12503.699999999999 12212.099999999999 13263.7 13418.9 12860.0 10098.1 16400.9 12824.2 11229.7 False True 12769.90045628039 16545.27650181974 12050.159574755606 10205.958887122231 11555.917362074439 12055.862167052903 10996.811337388193 13866.517760188759 13502.061030876812 10836.551621054661 1.178409968672079 1.5268027210495103 1.111992079781449 0.9418087269840313 1.0663832708204057 1.112518316585989 1.0147888112323629 1.2796061187257288 1.2459739502964442 1.0 13.403618118650938 -5.363800587865522 8.60040402123029 1.0968734857636424 1.351860757198483 0.3995719057844124 0.12559538758005462 0.2939203290196065 22.2191242768928 0.033401045864538625 0.06973943396185331 4.327124711604138e-06 5.363800587865522 0.2549872714348407 DDFNSGFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DDFNSGFR 8 0 Q15056 Q15056 EIF4H Eukaryotic translation initiation factor 4H 0 95.815 0.029077 2449700.0 10454.0 18056.0 13999.0 11521.0 13257.0 9679.1 12593.0 13597.0 11756.0 7352.3 False True 12223.655724088327 19848.48035205313 14332.789251503142 10875.515721585965 10659.386016170782 9171.510956918273 11400.099874575311 13240.093157212345 11927.909259833048 8685.21378922522 1.4074098831341215 2.2853185694377425 1.650251749621206 1.2521874516293439 1.2273026634525335 1.0559913871430946 1.3125871338617074 1.5244406733703963 1.3733581635757408 1.0 13.084345646419736 -5.631323953592822 4.05779868632106 1.2653619981329596 1.8720522792955339 0.5086313663340918 0.24277812437800914 0.16311523001917938 4.8880515488302105 0.06551404764128803 0.11901488960197465 2.3370932786463353e-06 5.631323953592822 0.6066902811625743 DDFTEFGK ddPTM_PC-9_Lapatinib_30min_R1 1 DDFTEFGK 8 0 O75822;O75822-3;H0YGJ7;H0YLP3 O75822 EIF3J Eukaryotic translation initiation factor 3 subunit J 0 92.439 0.036739 4740500.0 28718.0 28354.0 36524.0 24328.0 29268.0 27823.0 26498.0 30121.0 36755.0 26654.0 False True 28308.47605376379 28288.34805506457 33521.13770671718 26117.16227582894 27546.513783101964 26633.075148580796 27869.936784290254 31520.531622116658 32615.264852691427 31261.108385777457 0.9055493395954893 0.9049054725114809 1.0722952396009076 0.8354522160100758 0.8811752111654018 0.8519555615212213 0.8915210695782607 1.0082985936754958 1.0433176089025065 1.0 14.932081310616272 -7.804105204269041 6.203326278957863 1.0213062221678952 0.9066848989169508 0.40919677243036334 0.061177585266374165 0.20441100459174708 19.402147049184002 0.03527819666790304 0.017040583327792055 1.569982442921626e-08 7.804105204269041 -0.11462132325094443 DDGEMAAAGTFLHPFPSES(ph)VSDCVDSPPAAASGR ddPTM_PC-9_AZD4547_30min_R2 1 DDGEMAAAGTFLHPFPSESVSDCVDSPPAAASGR 34 0 U3KPY3 U3KPY3 SSBP4 1 DDGEMAAAGT(0.001)FLHPFPS(0.379)ES(0.485)VS(0.092)DCVDS(0.035)PPAAAS(0.008)GR 46.813 0.019752000000000002 0.0 1107.9 1404.0 1129.9 3231.3 3009.8 1492.1 1523.3 2712.3 1479.3 3026.7 True False 1460.1891542484318 1857.8155432835806 1114.9167877364546 2486.3737080873398 2591.941222929722 1398.7987511243896 1658.8707489768801 2293.1763574535526 1557.4927779491952 2920.736154255779 0.49993874048527215 0.6360778396831819 0.38172458204138676 0.8512832302446992 0.8874273765375988 0.4789199288289742 0.567963233022522 0.7851364301127253 0.5332535003820137 1.0 11.512116322343298 -14.522878745280336 0.29185889144829164 3.8804170842738626 0.6108407298619819 0.32851401733613306 0.15983937892531047 319.83388975500384 3.0015829042164723 561.9235507521325 0.17422389949412131 3.0000000000000132e-15 14.522878745280336 -3.2695763544118805 DDGLFSGDPNWFPK ddPTM_PC-9_AZD4547_30min_R2 2 DDGLFSGDPNWFPK 14 0 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 0 ; 214.04 1.2845e-14 10663700.0 52144.0 55632.0 99959.0 132511.0 100851.0 86083.0 79136.0 127915.0 93182.0 101528.0 False True 68724.70733742234 73613.95605694597 98633.47834794967 101962.63622454162 86849.57946497608 80700.21640174295 86178.95069325434 108148.67594427991 98107.41028517665 97973.53562271799 0.7014619499093236 0.7513657192124079 1.0067359284426871 1.0407161033484091 0.8864595823041574 0.823694030115519 0.8796145831167828 1.1038560082259858 1.001366436983291 1.0 16.580104484063526 -5.1924926289837 5.214189230811731 0.9628140615593973 0.7175838568754608 0.5947142703487718 0.07980489291535739 0.16501899895102112 8.569049502212456 0.022912321481735193 0.06349401589221915 6.419591169975176e-06 5.1924926289837 -0.24523020468393653 DDGLFSGDPNWFPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DDGLFSGDPNWFPK 14 0 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 0 ; 234.3 4.0283e-26 9776100.0 64122.0 72097.0 73364.0 77818.0 99630.0 73538.0 81302.0 72729.0 66188.0 65053.0 False True 74976.58813277136 79254.31368752618 75113.27599451941 73458.10974936002 80108.21669993908 69681.53782374962 73600.48598449328 70819.94081274532 67155.87428460614 76846.59394073521 0.9756657294478657 1.03133150896249 0.977444440184915 0.9559058636484472 1.042443296338147 0.9067615654831579 0.9577585968384577 0.921575533554061 0.8738952612056866 1.0 16.229693696541517 -6.775383024008596 24.999998621122554 0.9287066826984015 0.9951696909249679 0.40456330284977593 0.03904126321454742 231.95890424885926 415883.9132108883 0.01326029375922281 0.011751782941880274 1.6773240574057067e-07 6.775383024008596 0.06646300822656637 DDGLFSGDPNWFPK ddPTM_PC-9_Lapatinib_30min_R1 2 DDGLFSGDPNWFPK 14 0 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 0 ; 231.17 2.0391e-20 20849700.0 100653.0 84564.0 121087.0 97066.0 102431.0 100449.0 79883.0 86001.0 103926.0 93538.0 False True 99217.66976250021 84368.19725359658 111131.69426933693 104204.55744268381 96406.20996709431 96153.03042805559 84018.95086947913 89996.92042208622 92220.75949070357 109705.91866844958 0.9043966904133341 0.7690396131549838 1.012996341657703 0.9498535603863649 0.8787694514317927 0.8764616494270179 0.7658561351042422 0.8203469923448032 0.8406179047587286 1.0 16.743281836123955 -6.820189098895151 2.9599403539710307 0.8404813051344346 0.9057261933856887 0.051564966256723466 0.08030412310636327 0.5888792949377238 10.494779811929398 0.03023668615783997 0.027161136084748606 1.5129023626572293e-07 6.820189098895151 0.06524488825125407 DDGLFSGDPNWFPKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DDGLFSGDPNWFPKK 15 1 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 0 72.615 0.012199 3048900.0 27005.0 20519.0 22513.0 32812.0 33744.0 35570.0 31306.0 34928.0 28508.0 26728.0 False True 31576.413126937536 22555.99071465321 23049.79530102795 30973.65001793931 27132.105433330835 33704.64658259373 28340.4690441876 34011.177009275074 28924.87556816269 31573.574821268405 1.0000898949734136 0.7143945797185809 0.7300343857643032 0.9809991486005261 0.8593295370232916 1.0674954221493411 0.8976008958319494 1.0772038706990084 0.9161102514333754 1.0 14.946429994173767 -5.7757373073048806 24.923933534547032 0.9707436608105593 0.8047951197839299 0.3512952367129065 0.09711079437182629 220.24379760556383 383925.25761228736 0.026395111727714256 0.03935673294487216 1.6759563090169933e-06 5.7757373073048806 -0.16594854102662937 DDGSWEVIEGYR ddPTM_PC-9_AZD4547_30min_R2 3 DDGSWEVIEGYR 12 0 P49448;P00367 P49448 GLUD2;GLUD1 Glutamate dehydrogenase 2, mitochondrial;Glutamate dehydrogenase 1, mitochondrial 0 ;; 139.15 0.00019051 9422000.0 30004.1 24951.7 30000.9 38995.3 37878.4 29521.1 27357.8 37297.6 31179.1 27134.8 False True 39544.7796759503 33016.84906791233 29603.068463760188 30005.536056379267 32619.637988777067 27675.140950216613 29792.591200918872 31534.112933583878 32827.16357260577 26184.818911190327 1.5102178025394124 1.2609156924053528 1.1305431809233952 1.145913445426049 1.245746174507121 1.0569154991707574 1.1377810670360118 1.2042898994465636 1.2536715905480933 1.0 14.676443006989718 -4.790222323317627 2.409224152159368 1.1542883917611761 1.5894414699026986 0.6868128525577637 0.07439936662915463 0.3086801324736451 2.251451364008802 0.018998099384221836 0.2826486495693985 1.6209800754683834e-05 4.790222323317627 0.4351530781415225 DDGSWEVIEGYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DDGSWEVIEGYR 12 0 P49448;P00367 P49448 GLUD2;GLUD1 Glutamate dehydrogenase 2, mitochondrial;Glutamate dehydrogenase 1, mitochondrial 0 113.44 0.0038381 1363200.0 6887.1 7107.3 8123.7 8929.9 10183.0 8714.9 8942.2 7407.9 7760.8 5880.0 False True 8052.950003574584 7812.865773490656 8317.399817303818 8429.586654126415 8187.714249277135 8257.875302295362 8095.130080078402 7213.450474318846 7874.287018008876 6945.9974539456125 1.159365527696843 1.1248011283178092 1.1974377866463501 1.2135890791808543 1.1787672402076934 1.1888681729367103 1.1654381006834424 1.038504624014987 1.1336438100097426 1.0 12.761966166562525 -8.176535200654673 0.8535175963073265 1.013611718903123 1.180081702161217 0.6419698053326787 0.03960027700194304 0.3568112378068021 0.5381091486163765 0.03787906819869048 0.014409267994485197 6.659855393160329e-09 8.176535200654673 0.16646998325809403 DDGSWEVIEGYR ddPTM_PC-9_Lapatinib_30min_R1 2 DDGSWEVIEGYR 12 0 P49448;P00367 P49448 GLUD2;GLUD1 Glutamate dehydrogenase 2, mitochondrial;Glutamate dehydrogenase 1, mitochondrial 0 ; 141.89 0.0003676 6777500.0 43334.0 49162.0 45353.0 33237.0 43848.0 39631.0 34883.0 38270.0 44836.0 33428.0 False True 42716.04921351769 49048.1684095043 41624.25140764274 35681.359855381714 41268.94684848484 37936.074514373235 36689.07105617015 40048.16391150376 39786.097535988905 39205.98525998981 1.0895287780743506 1.2510377709996887 1.0616810451673766 0.9100998130455092 1.052618537063021 0.9676092633000979 0.9358028069661037 1.021480869462383 1.0147965233408152 1.0 15.258786295261405 -5.499518417187676 6.847271632889153 0.9866001784886762 1.1679646860331356 0.6545222604587939 0.05330946702622639 0.09645829720616722 18.274954956389912 0.013374748532574064 0.02653930656007989 3.165786208640929e-06 5.499518417187676 0.18136450754445943 DDGTGQLLLPLSDAR ddPTM_PC-9_AZD4547_30min_R2 1 DDGTGQLLLPLSDAR 15 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 86.803 0.035079 0.0 1584.8 4448.4 5364.3 5131.1 4720.3 7999.8 5039.6 4255.3 4870.2 4158.2 False True 2088.7334341122073 5886.25830679678 5293.1658770286485 3948.204169704747 4064.9678233089107 7499.571241367792 5488.11463700117 3597.7411620661783 5127.62882928964 4012.6226836575784 0.5205407033706665 1.4669354112884965 1.3191287330818335 0.983946032549935 1.013045118810827 1.8689948775676553 1.3677126083528626 0.8966058973645565 1.277874655439996 1.0 11.97032978715213 -4.75077943309795 24.827619196934005 1.2510050975828968 0.5205390258167738 0.38102104160706707 0.2764179384800871 469.99402804638163 1094563.8364581699 0.0713772424886301 1.0036264151337293 1.7750907745586846e-05 4.75077943309795 -0.730466071766123 DDGTGQLLLPLSDAR ddPTM_PC-9_Lapatinib_30min_R1 2 DDGTGQLLLPLSDAR 15 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 148.89 0.00060211 5111200.0 22760.0 22008.0 22297.5 22196.0 21318.0 17833.7 20758.0 17575.5 19636.199999999997 19530.8 False True 22435.43822632717 21957.04182816748 20464.28562083907 23828.36788368542 20064.117152800583 17070.99422338518 21832.74767032595 18392.121892517232 17424.56437764711 22906.67275684485 0.9794280672920134 0.9585434803754461 0.8933766085571742 1.0402369709745451 0.8759070933514397 0.7452411096362354 0.9531173689903089 0.8029154686824342 0.7606763567371606 1.0 14.48348029887286 -6.505703490764446 23.68540737085615 0.8423906690470102 0.9614262484567322 0.31034703054594837 0.08120894024989037 429.03935764432475 591664.4619431463 0.024414683131128174 0.027011196746215542 3.121019694808484e-07 6.505703490764446 0.11903557940972198 DDGVFVQEVTQNS(ph)PAAR ddPTM_PC-9_AZD4547_30min_R2 4 DDGVFVQEVTQNSPAAR 17 0 Q09666;E9PJZ0;E9PKR9;E9PJC6;E9PLK4;Q09666-2;E9PQE3 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 DDGVFVQEVTQNS(1)PAAR;DDGVFVQEVTQNS(1)PAAR;DDGVFVQEVTQNS(1)PAAR;DDGVFVQEVT(0.009)QNS(0.991)PAAR 310.98 1.3245999999999996e-129 162087000.0 151650.0 155095.0 183997.0 232168.0 215870.0 194300.0 144819.0 226125.0 160971.0 176130.0 True False 199871.54548404587 205226.42570197055 181557.07955849613 178645.25455984316 185900.17668743434 182150.39028447735 157707.61044842337 191182.57708556775 169479.59843119045 169963.74230979994 1.1759657840419384 1.2074717990610955 1.0682106494664287 1.0510786131916245 1.0937637296111449 1.0717014570817363 0.9278897269804943 1.124843301797223 0.9971514872994087 1.0 17.374867489218246 -5.339209605286997 4.046074700390764 1.0434917101427188 1.1925416097311285 0.5636845762538147 0.05302197195519585 0.1543928850946147 4.746603694339297 0.013785134363721543 0.03179085650396118 4.579208252091337e-06 5.339209605286997 0.14904989958840975 DDGVFVQEVTQNS(ph)PAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DDGVFVQEVTQNSPAAR 17 0 Q09666;E9PJZ0;E9PKR9;E9PJC6;E9PLK4;Q09666-2;E9PQE3 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 DDGVFVQEVT(0.003)QNS(0.997)PAAR;DDGVFVQEVTQNS(1)PAAR;DDGVFVQEVTQNS(1)PAAR;DDGVFVQEVTQNS(1)PAAR;DDGVFVQEVT(0.007)QNS(0.993)PAAR;DDGVFVQEVTQNS(1)PAAR 300.86 1.0987999999999998e-112 143208800.0 103643.0 104567.0 120329.1 104248.6 129874.0 97494.8 118255.0 88340.8 89455.2 74866.5 True False 121187.71285744084 114947.72070077229 123198.20209465295 98407.8889205213 104426.12200831005 92382.0010582137 107053.03030794114 86021.94760481463 90763.31306738858 88439.20380711227 1.370294028446409 1.29973717257197 1.3930270376851286 1.1127179427706173 1.1807673239128835 1.0445820075415961 1.2104703084101256 0.9726675942541305 1.0262791743958397 1.0 16.43239841659073 -5.867126951363903 0.4511298143330113 0.9995226417914809 1.468651946754229 0.7411329301398577 0.07462936660863934 1.0231175367934844 0.3208815017842121 0.06196633829247386 0.2344019936419565 1.3579164474291715e-06 5.867126951363903 0.4691293049627481 DDGVFVQEVTQNS(ph)PAAR ddPTM_PC-9_Lapatinib_30min_R1 4 DDGVFVQEVTQNSPAAR 17 0 Q09666;E9PJZ0;E9PKR9;E9PJC6;E9PLK4;Q09666-2;E9PQE3 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 DDGVFVQEVTQNS(1)PAAR;DDGVFVQEVTQNS(1)PAAR;DDGVFVQEVTQNS(1)PAAR;DDGVFVQEVTQNS(1)PAAR 284.84 8.720099999999998e-97 141002000.0 171697.0 162343.0 196214.0 140652.0 146602.0 149241.0 117761.0 105532.0 158660.0 102703.0 True False 169248.5692946267 161967.10475782424 180082.04232794367 150996.01728131724 137979.15859062164 142858.3103277629 123858.08837100168 110435.40198350727 140790.0400361318 120455.07670685458 1.405076265125117 1.344626637464151 1.4950141351551351 1.2535463129444397 1.1454823023060665 1.1859882890235498 1.0282512929897412 0.9168181616144607 1.1688178189348166 1.0 16.878135673205882 -6.374225847694613 1.0505508827898422 1.028037770778547 1.4170653593525393 0.7873116746963873 0.08072470232120309 0.22798631695397653 0.5325125110708683 0.03755005132281542 0.05082040874414178 4.224488695542954e-07 6.374225847694613 0.3890275885739922 DDGVFVQEVTQNSPAAR ddPTM_PC-9_Lapatinib_30min_R1 1 DDGVFVQEVTQNSPAAR 17 0 Q09666;E9PJZ0;E9PKR9;E9PJC6;E9PLK4;Q09666-2;E9PQE3 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 105.58 0.0072755 0.0 6134.0 7970.9 10043.0 9556.8 9932.9 9746.7 7267.3 7666.5 7929.8 7062.1 False True 6046.528035162167 7952.44387078064 9217.303307101101 10259.638952550229 9348.666350832767 9329.856361667418 7643.565234828004 8022.713577934248 7036.662419504083 8282.774575343255 0.7300123865693382 0.9601183514584634 1.1128279809207673 1.2386717589890521 1.1286877683068344 1.1264167914748264 0.9228266645795123 0.9686021881866524 0.849553776394122 1.0 13.015898409339657 -7.27852549855869 23.948186791807625 0.9326291479165445 1.0604777710705302 0.14818693623763202 0.13251569261552523 965.4605175103468 1353198.1103189746 0.06038401871904008 0.04084313826464991 5.265922963827968e-08 7.27852549855869 0.1278486231539857 DDHDDFFST(ph)TPLQHQR ddPTM_PC-9_Lapatinib_30min_R1 1 DDHDDFFSTTPLQHQR 16 0 Q6P0N0 Q6P0N0 MIS18BP1 Mis18-binding protein 1 1 DDHDDFFS(0.007)T(0.886)T(0.107)PLQHQR 98.573 0.020554 1453700.0 6531.0 9507.7 8285.2 7071.4 10133.0 8936.4 10209.0 9537.2 8212.7 7077.3 True False 6437.866742361285 9485.685504801348 7604.022837796876 7591.454345498878 9536.996862244496 8554.211003765859 10737.572066979365 9980.333129260347 7287.699242435012 8300.601875090526 0.7755903534755513 1.1427708071708833 0.9160809001833915 0.9145667338027926 1.1489524501668122 1.030553101147568 1.2935895768235797 1.2023625852012692 0.8779723870753087 1.0 13.019000234462208 -6.2606172910912425 24.99998630610679 1.1093397801469347 0.9504198602469304 0.2289620565254823 0.1363424561156966 111.7562348950969 3398543.873285774 0.04072320229295139 0.04949124742061079 5.487603303980624e-07 6.2606172910912425 -0.15891991990000431 DDHDDFFSTT(ph)PLQHQR ddPTM_PC-9_AZD4547_30min_R2 1 DDHDDFFSTTPLQHQR 16 0 Q6P0N0 Q6P0N0 MIS18BP1 Mis18-binding protein 1 1 DDHDDFFS(0.005)T(0.193)T(0.803)PLQHQR 100.77 0.017503 1292500.0 6424.1 6327.0 8597.6 11087.0 8091.2 9951.3 7545.6 12737.0 7996.4 7906.6 True False 8466.830170419122 8372.079018771525 8483.59020642796 8531.063442442472 6967.876544278346 9329.043637868863 8217.143782235902 10768.789317142602 8419.073379025851 7629.792340581738 1.1097065021527917 1.097287926729234 1.1119031590551942 1.118125246616085 0.9132458962503134 1.2227126534295119 1.0769813142266178 1.4114131599447344 1.1034472503591013 1.0 12.897428076546293 DDISEIQSLAS(ph)DHSGR ddPTM_PC-9_AZD4547_30min_R2 1 DDISEIQSLASDHSGR 16 0 A0A087X0K9;G5E9E7;Q07157-2;H0YKB1;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 DDISEIQSLAS(0.933)DHS(0.066)GR 91.64 0.006993200000000001 0.0 5450.1 5348.3 7325.7 5006.8 6870.8 8423.7 7739.0 8871.1 7490.3 4841.2 True False 7183.118430877671 7077.033383293142 7228.556431472649 3852.5596142888935 5916.908018640953 7896.96470735642 8427.756007570455 7500.2753325982385 7886.221966249475 4671.711061546596 1.5375776318879746 1.5148696676780884 1.5473038328444042 0.824657082498052 1.2665398053710384 1.6903795211902692 1.803997699459692 1.6054664412647195 1.6880799908971034 1.0 12.189735333074289 -6.759574121636705 24.991811361180186 1.6108272067095262 1.3310930173181035 0.11607051419391767 0.2839984943115968 89.37026059423327 1197439.6328276184 0.09785900314509746 0.09315050339538639 1.7395057888559587e-07 6.759574121636705 -0.2797341893914227 DDISEIQSLAS(ph)DHSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DDISEIQSLASDHSGR 16 0 A0A087X0K9;G5E9E7;Q07157-2;H0YKB1;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 DDISEIQS(0.105)LAS(0.661)DHS(0.234)GR 90.71799999999999 0.0072786000000000005 0.0 4681.0 12071.0 7925.4 6551.1 7865.9 5751.8 8475.7 4947.3 5419.9 5275.6 True False 5473.400846035718 13269.32910554018 8114.371593246871 6184.06310595276 6324.633360835615 5450.165482534794 7672.820337245931 4817.438617097646 5499.15578405658 6232.024518373376 0.8782701078756882 2.1292164474673174 1.3020442344737129 0.9923040398382236 1.0148601537412454 0.874541726603692 1.2311922577686871 0.7730134249142923 0.8824027838536036 1.0 12.605485194002956 -5.624772342955885 4.065884508860954 0.9672217704532038 1.5477423270776536 0.34141532312133094 0.303628642540493 0.20447715821231496 6.1889326305591 0.07874507499182556 0.14342557822895127 2.3726171049512207e-06 5.624772342955885 0.5805205566244498 DDISEIQSLAS(ph)DHSGR ddPTM_PC-9_Lapatinib_30min_R1 2 DDISEIQSLASDHSGR 16 0 A0A087X0K9;G5E9E7;Q07157-2;H0YKB1;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 DDISEIQS(0.027)LAS(0.963)DHS(0.01)GR;DDISEIQSLAS(0.829)DHS(0.171)GR 103.73 0.00095864 950910.0 7786.799999999999 10234.2 9817.8 8848.7 11322.9 11593.900000000001 10355.3 13542.0 11584.5 11043.4 True False 7675.758804075769 10210.503338687378 9010.618381803955 9499.462916397877 10656.909283677913 11098.055923700937 10891.446765127957 14171.210757501536 10279.73161980693 12952.236975594471 0.5926203186784631 0.7883196823781666 0.6956804757959884 0.7334225689583539 0.8227852303627876 0.8568447245531938 0.8408931048474791 1.0941129925436002 0.7936645723187997 1.0 13.660913666255883 -6.554834275182561 0.5338342936955607 0.9767117092642197 0.6487561974995437 0.6058067482923581 0.08554780362043192 0.6878388788514643 0.4168804281976529 0.06837643737996607 0.10513969182549875 2.7871845427904346e-07 6.554834275182561 -0.32795551176467597 DDKEEEEDGTGS(ph)PQLNNR ddPTM_PC-9_AZD4547_30min_R2 1 DDKEEEEDGTGSPQLNNR 18 1 P49407-2;P49407 P49407-2 ARRB1 Beta-arrestin-1 1 DDKEEEEDGT(0.122)GS(0.878)PQLNNR 59.537 0.013498 7021400.0 34220.0 40648.0 37530.0 37062.0 43104.0 42795.0 38985.0 40888.0 45010.0 40363.0 True False 45101.24817978274 53786.67108503633 37032.327678333626 28517.928502191993 37119.753629198836 40119.02188483896 42454.589476047855 34569.69911276808 47389.13671026383 38949.90365554105 1.1579296467236986 1.3809192330924955 0.9507681458171046 0.7321694234315521 0.9530127200691585 1.0300159466281913 1.0899793193713903 0.8875426090521321 1.21666890704933 1.0 15.249332139265276 -5.2721878043515495 24.89391284514508 0.9740425337354434 1.269424439939769 0.43844580431300906 0.12959424898585759 530.1961324229916 1227963.2700519052 0.034442756483516766 0.07288243869421074 5.343332447654726e-06 5.2721878043515495 0.2953819062043256 DDKEEEEDGTGS(ph)PQLNNR ddPTM_PC-9_Lapatinib_30min_R1 1 DDKEEEEDGTGSPQLNNR 18 1 P49407-2;P49407 P49407-2 ARRB1 Beta-arrestin-1 1 DDKEEEEDGT(0.031)GS(0.969)PQLNNR 114.87 6.455399999999999e-05 11216000.0 29687.0 39389.0 31790.0 37434.0 43391.0 38231.0 41157.0 42712.0 40843.0 37983.0 True False 29263.657936070955 39297.79719055297 29176.348912948702 40187.02123616329 40838.82668998829 36595.94925081383 43287.90807725239 44696.55544782202 36242.83124414301 44548.310940833864 0.6568971374680629 0.8821388816008248 0.6549372646630488 0.9020997740977664 0.9167312032150384 0.8214890414008774 0.971707056070982 1.0033277245277614 0.8135624107562317 1.0 15.443083112228678 -2.822355821654116 0.24537729090733323 0.9813143406933439 1.4867651685799513e-17 0.4644033088039857 0.08812300782372476 24.471292757072973 0.5741644291603286 0.11746654118610236 8.637265254662859 0.0015053731940296445 2.822355821654116 -0.9813143406933439 DDPVTNLNNAFEVAEK ddPTM_PC-9_Lapatinib_30min_R1 1 DDPVTNLNNAFEVAEK 16 0 O43707;K7EJH8 O43707 ACTN4 Alpha-actinin-4 0 226.93 4.4626e-28 3569300.0 10853.0 11339.0 14903.0 14097.0 12300.0 9915.3 11863.0 7755.8 13391.0 10577.0 False True 10698.234229803551 11312.74524216608 13677.732867243622 15133.740406213445 11576.538182730426 9491.24573269321 12477.208093895195 8116.162781939923 11882.764566518601 12405.220357033404 0.8623977585160717 0.911934243534181 1.1025787913141534 1.2199493415393503 0.9331989154200603 0.7651009381152949 1.005803019599001 0.6542538180176938 0.9578841991131108 1.0 13.598659741960427 -6.517877415983849 24.86869381656716 0.8615267969544321 1.0286401079994838 0.20365348175759945 0.13596255685823228 301.68389241900826 1500107.9946225814 0.04477806024911949 0.0460015098689966 3.034747651576566e-07 6.517877415983849 0.16711331104505167 DDQRS(ph)TPDSTYSESFK ddPTM_PC-9_AZD4547_30min_R2 1 DDQRSTPDSTYSESFK 16 1 Q6ISB3-2;Q6ISB3 Q6ISB3-2 GRHL2 Grainyhead-like protein 2 homolog 1 DDQRS(0.98)T(0.02)PDSTYSESFK 122.44 2.7451e-05 16565000.0 16136.0 23377.0 26138.0 23484.0 24165.0 24900.0 21265.0 23600.0 23685.0 24171.0 True False 21266.912350349943 30933.1580878492 25791.393041734187 18070.126624183173 20810.106868262596 23342.99906373385 23157.543804236433 19953.162274049264 24936.940746114153 23324.7806470798 0.9117733054871195 1.3261928828351897 1.1057507220314717 0.7747179661664044 0.8921887490876775 1.0007810755835052 0.992830078645807 0.8554490855007182 1.0691179104072814 1.0 14.509575893172755 -5.571327437340731 13.482356517016472 0.9375316470065295 1.143219486973617 0.29271661486865375 0.1227290441539422 1.352274953859851 375.0339308488767 0.03197434570316265 0.05539264721311303 2.683320586973286e-06 5.571327437340731 0.2056878399670875 DDQRS(ph)TPDSTYSESFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DDQRSTPDSTYSESFK 16 1 Q6ISB3-2;Q6ISB3 Q6ISB3-2 GRHL2 Grainyhead-like protein 2 homolog 1 DDQRS(0.5)T(0.5)PDSTYSESFK;DDQRS(0.5)T(0.5)PDSTYSESFK 75.743 0.0056902 23196000.0 43303.0 32712.6 41552.0 49391.0 52754.0 32636.7 45302.0 37815.0 41129.3 38171.3 True False 50633.34262676454 35960.090737958206 42542.75726683755 46623.78239778248 42417.23239775767 30925.173998373255 41010.66660192256 36822.39631830443 41730.73820350899 45091.454526155474 1.1229032897440572 0.7974923655900125 0.9434771557914695 1.0339826667320784 0.9406933718040386 0.6858322563188771 0.9094997496284837 0.81661584673312 0.9254688863341703 1.0 15.460566427644778 -6.546480464461543 24.999290170545432 0.8536050717341304 0.9630758329242609 0.17265658620062152 0.10844842372367243 383.5263830246002 406233.9190375165 0.03440611907917831 0.03440773393898876 2.8413159908655054e-07 6.546480464461543 0.10947076119013055 DDQRS(ph)TPDSTYSESFK ddPTM_PC-9_Lapatinib_30min_R1 1 DDQRSTPDSTYSESFK 16 1 Q6ISB3-2;Q6ISB3 Q6ISB3-2 GRHL2 Grainyhead-like protein 2 homolog 1 DDQRS(0.5)T(0.5)PDSTYSESFK 109.54 0.00031667 15204000.0 26228.0 33326.0 40312.0 35174.0 41810.0 34334.0 33223.0 36336.0 43539.0 38679.0 True False 25853.98391037387 33248.83569454335 36997.70296882003 37760.8132970243 39350.8180016227 32865.614856463144 34943.12437861252 38024.30321108966 38635.1793340044 45364.613613472124 0.5699152235851052 0.732924476726267 0.8155630572335055 0.8323847662136885 0.867434215067061 0.7244769047631192 0.7702727212964801 0.8381930359877995 0.8516589530155448 1.0 15.46927975040286 -3.1093489850142864 0.059852282287486167 1.2757490780333485 3.5969526909246086e-19 0.6097703040109896 0.06669518366083797 209.5289725918539 1.2814018606084954 6.888458452818765 25.622088902530905 0.000777411597134537 3.1093489850142864 -1.2757490780333485 DDQRST(ph)PDSTYSESFK ddPTM_PC-9_AZD4547_30min_R2 1 DDQRSTPDSTYSESFK 16 1 Q6ISB3-2;Q6ISB3 Q6ISB3-2 GRHL2 Grainyhead-like protein 2 homolog 1 DDQRS(0.354)T(0.646)PDSTYSESFK 100.07 0.0013165999999999998 15396000.0 21669.0 17121.0 25271.0 25771.0 27591.0 26460.0 19651.0 25417.0 20315.0 22710.0 True False 28559.29125680047 22655.028430597 24935.89002822194 19829.894107980952 23760.465905327248 24805.45201712442 21399.900930968743 21489.38667455551 21388.809426105516 21914.92981238602 1.3031888078719351 1.0337714345675288 1.1378494132401242 0.9048577512109286 1.0842136437917385 1.131897397321561 0.9764987209255769 0.980582044228588 0.97599260454929 1.0 14.419626437856015 -2.1839748900106057 1.2194504977303415 1.0196304044450075 199.99985991731862 0.5782152178786513 0.0708896267432517 767.2565309287173 2.190618222977981 0.02126369149713833 425843.44179849187 0.006546740248420018 2.1839748900106057 198.98022951287362 DDQRST(ph)PDSTYSESFK ddPTM_PC-9_Lapatinib_30min_R1 1 DDQRSTPDSTYSESFK 16 1 Q6ISB3-2;Q6ISB3 Q6ISB3-2 GRHL2 Grainyhead-like protein 2 homolog 1 DDQRS(0.267)T(0.732)PDSTYSESFK 73.984 0.009789 15248000.0 21202.0 27602.0 35981.0 35580.0 37496.0 31255.0 35975.0 32045.0 32499.0 32887.0 True False 20899.655592029383 27538.089264861836 33022.78107067653 38196.67189140057 35290.55899997236 29918.296508963576 37837.60947297313 33533.92768602399 28838.620390358283 38571.47413082704 0.5418422827486904 0.713949619126765 0.8561451646537955 0.9902829163812819 0.9149393378192795 0.7756586229369004 0.9809739017138732 0.8693970982878005 0.7476670529247396 1.0 15.235246663721817 -4.984558355176404 2.049647504499779 0.8923208503824621 0.513943782999048 0.6595563454280726 0.0808998619111552 0.28632248866587345 1.8244573895291512 0.02211666765743149 0.17490080778489367 1.0361953638273076e-05 4.984558355176404 -0.37837706738341415 DDS(ph)FDSLDSFGSR ddPTM_PC-9_AZD4547_30min_R2 1 DDSFDSLDSFGSR 13 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 DDS(0.814)FDS(0.185)LDS(0.001)FGSR 93.649 0.017011000000000002 0.0 2776.5 2757.5 2742.5 3952.3 3896.6 2311.2 3512.8 3423.9 2765.9 2051.4 True False 3659.369245212355 3648.807949148483 2706.1326580823325 3041.158297426298 3355.6243502119605 2166.6802986386224 3825.4323948046926 2894.814928394799 2912.0998273032365 1979.5811103975652 1.8485573670065143 1.8432222503960356 1.3670228736113024 1.5362635465922045 1.6951183927684783 1.0945145350490244 1.932445391962959 1.4623371142460664 1.4710687084291236 1.0 10.950979465528954 -12.510303519546168 0.14339964815277634 7.055182296438624e-20 1.8071288735620143 0.39257383985905925 0.2330017764100789 77.91914658347518 1.1768920999847723 26.32688086176413 1.517244116140969 3.0881364426569426e-13 12.510303519546168 1.8071288735620143 DDS(ph)LDLSPQGR ddPTM_PC-9_Lapatinib_30min_R1 2 DDSLDLSPQGR 11 0 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 DDS(0.681)LDLS(0.319)PQGR;DDS(0.999)LDLS(0.001)PQGR 119.21 0.0009872 3905100.0 26363.0 35830.0 36487.0 27025.0 31735.0 33773.0 26727.0 26286.0 33724.0 27116.0 True False 25987.0587856179 35747.037836388656 33487.17970389304 29012.508652757195 29868.409693410562 32328.607518708257 28110.79328378465 27507.343521760864 29925.647990536425 31802.964470201143 0.817126931986713 1.1240159032936394 1.0529578063475804 0.9122579965758048 0.9391706147833097 1.016528114824001 0.8839048105129949 0.8649301717622832 0.9409703934542413 1.0 14.95687363018872 -5.771567422255819 24.996172963807933 0.9324091619850591 1.0106317867921653 0.09251839291828867 0.08436069941082795 378.93985546336836 935230.5170829744 0.023483329731506138 0.035292032651134876 1.6921255292022635e-06 5.771567422255819 0.07822262480710618 DDS(ph)PDEVPSTFTVQQPPPSR ddPTM_PC-9_AZD4547_30min_R2 1 DDSPDEVPSTFTVQQPPPSR 20 0 P0DP91;Q8N328 P0DP91 PGBD3 PiggyBac transposable element-derived protein 3 1 DDS(1)PDEVPSTFTVQQPPPSR 87.15700000000001 0.00073871 1834600.0 3305.2 4399.3 3889.8 2459.0 3623.1 4378.2 6032.0 4262.9 4367.0 4317.7 True False 4356.1848475691995 5821.287691999615 3838.218710449829 1892.115541171283 3120.0951042583133 4104.43046188111 6568.836314467628 3604.1667566968035 4597.830704592804 4166.538637205599 1.0455164890756399 1.397151976467406 0.9212007963099157 0.4541216837101698 0.7488458348608735 0.9850935798914987 1.5765691588241681 0.8650266013407317 1.1035132768327003 1.0 12.024633643242122 -7.013776687790483 24.419770313843323 1.147286875895256 0.9103461797054255 0.12454646174031392 0.27877510002611283 1103.5702171759856 1956123.9859964442 0.1132532051336779 0.09162370624658171 9.68775868273458e-08 7.013776687790483 -0.23694069618983038 DDS(ph)PVSHR ddPTM_PC-9_AZD4547_30min_R2 2 DDSPVSHR 8 0 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8YFE7 Q14004 CDK13 Cyclin-dependent kinase 13 1 DDS(1)PVSHR;DDS(1)PVSHR 85.355 0.0075309 6572200.0 75123.0 78037.0 57313.0 36125.0 47827.0 66859.0 65700.0 52783.0 91685.0 74771.0 True False 99010.55134453026 103260.93415329124 56552.99217235104 27796.939375686296 41187.04660411314 62678.29616073018 71547.17272223525 44626.600182675546 96531.28192136271 72153.29004852129 1.372225040298899 1.4311327187415963 0.7837895144396128 0.3852483976405448 0.5708270070071078 0.868682441487846 0.9915995885166368 0.618497093516668 1.3378638986032074 1.0 16.138777559830274 -5.262790742337481 24.999999843092294 0.7894420700783322 1.4016789269053669 0.4574592639480981 0.2518734044703443 95.46124242244504 1766057.3641717373 0.06684614558462824 0.15262328309281822 5.460208889149181e-06 5.262790742337481 0.6122368568270347 DDS(ph)PVSHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DDSPVSHR 8 0 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8YFE7 Q14004 CDK13 Cyclin-dependent kinase 13 1 DDS(1)PVSHR;DDS(1)PVSHR 69.01 0.023822 6132100.0 35557.0 85776.0 44610.0 35413.0 76521.0 51741.0 43703.0 26784.0 47960.0 56553.0 True False 41576.09781723824 94291.2744061648 45673.671584367105 33428.92442049508 61527.25936059472 49027.610875175196 39563.13545768005 26080.94837999378 48661.3242685942 66805.61122669825 0.6223443967326914 1.4114274635733315 0.6836801691609108 0.5003909672655688 0.9209893934179875 0.7338846239847254 0.5922127607429031 0.3904005651784347 0.7284017521143067 1.0 16.02768166411923 -5.466827398875013 24.92016736475829 0.6700149905817189 1.024553483214608 0.21219254571046808 0.24572748124996094 352.3838305034422 156667.13038076594 0.06117654501483899 0.12734836734551255 3.4132853845287924e-06 5.466827398875013 0.35453849263288906 DDS(ph)PVSHR ddPTM_PC-9_Lapatinib_30min_R1 2 DDSPVSHR 8 0 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8YFE7 Q14004 CDK13 Cyclin-dependent kinase 13 1 DDS(1)PVSHR;DDS(1)PVSHR 83.397 0.0085649 8332900.0 26398.0 57832.0 33867.0 46385.0 61815.0 41831.0 69177.0 75396.0 48204.0 46148.0 True False 26021.5596791997 57698.09355718749 31082.58599040057 49796.30763582398 58179.16323296594 40041.98564282369 72758.64657433945 78899.17340663001 42774.75790937663 54124.62031165522 0.4807712188901251 1.0660230635329326 0.5742781346349183 0.9200306135930679 1.0749112492238142 0.7398109291530869 1.3442800366152696 1.4577316746486224 0.790301302126003 1.0 15.723997378808425 -6.420770607104954 0.9634169446863212 1.148654061323478 0.7292973595417358 0.2794609960409159 0.2513023770187046 0.7126617559013348 1.4253827039567863 0.12562865586333316 0.16577173209817098 3.7951539080423577e-07 6.420770607104954 -0.4193567017817421 DDS(ph)QNAIDHK ddPTM_PC-9_Lapatinib_30min_R1 1 DDSQNAIDHK 10 0 Q6PL18;A0A0B4J211 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 DDS(1)QNAIDHK 71.279 0.031531 0.0 15777.0 21975.0 17565.0 20128.0 19686.0 19616.0 19573.0 22687.0 21545.0 18067.0 True False 15552.01708685255 21924.118237639963 16120.873502860773 21608.280265039644 18528.108184165136 18777.069407129395 20586.39416857547 23741.120842965403 19118.37522109201 21189.85687723573 0.7339368631394622 1.034651548835757 0.7607825572516931 1.0197463999038818 0.8743857163126897 0.8861347915615989 0.9715211522118132 1.1204002452923831 0.9022418288077674 1.0 14.371086222889566 -7.393342582049411 4.245297630355006 1.0143825799481023 0.8920390839155831 0.23112437999703717 0.10178479739306676 0.33132747664826745 9.84296163195763 0.04160418040536751 0.027062592528996777 4.0425687823407634e-08 7.393342582049411 -0.12234349603251926 DDSFDSLDS(ph)FGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DDSFDSLDSFGSR 13 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 DDSFDS(0.05)LDS(0.949)FGSR;DDSFDS(0.001)LDS(0.999)FGSR 128.35 0.00083405 0.0 9050.5 12770.3 9483.7 9648.2 10830.9 10232.8 9169.5 9261.2 6815.4 7940.7 True False 10582.570894476881 14038.050988027479 9709.827375132536 9107.642633886442 8708.662895266205 9696.173954185128 8300.898578568911 9018.103313052516 6915.062331529952 9380.286051453391 1.1281714476966518 1.4965482833918917 1.035131265919986 0.9709344239534459 0.9284005676902439 1.033675721720959 0.8849302178031939 0.9613889452396008 0.7371909868845125 1.0 13.195416203001969 -5.446219768144597 5.12080386964154 0.9357895195522874 1.3104258857562185 0.6412287555225309 0.1123804800621602 0.12132429902748353 5.657836044860594 0.028197550628952916 0.05963898568860098 3.5791527366586173e-06 5.446219768144597 0.37463636620393115 DDSFDSLDS(ph)FGSR ddPTM_PC-9_Lapatinib_30min_R1 1 DDSFDSLDSFGSR 13 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 DDSFDS(0.044)LDS(0.946)FGS(0.01)R 89.26 0.026331 0.0 5209.9 5476.7 5293.3 3796.4 6763.3 5629.9 6440.6 5065.4 7491.7 5669.2 True False 5135.605870621353 5464.019037637448 4858.105306728892 4075.5999204191457 6365.495991159401 5389.122300937897 6774.0627539021725 5300.756976151845 6647.905854901602 6649.113666265838 0.7723745040901856 0.8217665258693129 0.7306395334127621 0.6129538649785204 0.9573450403554737 0.8105023573712561 1.0187918411246693 0.7972125672997805 0.9998183500200388 1.0 12.698946325350246 -6.280522628370933 24.913690810904647 0.9188758702092658 0.7404006591201362 0.5488642999137479 0.08667374373059579 639.5758979019189 834981.2722088494 0.026124144839082184 0.029669794951674867 5.241762887468446e-07 6.280522628370933 -0.17847521108912956 DDSFDSLDSFGS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 DDSFDSLDSFGSR 13 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 DDSFDS(0.001)LDS(0.246)FGS(0.753)R 117.48 0.00025804 1407600.0 4021.3 4683.7 6759.9 6527.5 6921.8 6852.7 4558.9 7490.8 4141.5 5780.8 True False 5299.989751763894 6197.6144302544935 6670.259309159805 5022.685723869686 5960.827548965027 6424.199585704781 4964.633268240464 6333.2689814596715 4360.411234960179 5578.415951538578 0.9500886627685244 1.1109989796557094 1.1957264153670875 0.900378488714952 1.0685520048609813 1.1516171690160408 0.8899718686038771 1.1353167344419517 0.7816576018784576 1.0 12.445639796806846 -8.256031039909498 24.984438188730604 0.8908288013799845 1.0508398620849118 0.24605370764469414 0.11167901344678734 554.3287932713123 2560815.4484525593 0.07692364949607051 0.027162862658344656 5.545860741472582e-09 8.256031039909498 0.1600110607049272 DDSHSAEDS(ph)EDEKEDHK ddPTM_PC-9_Lapatinib_30min_R1 1 DDSHSAEDSEDEKEDHK 17 1 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 DDS(0.001)HS(0.003)AEDS(0.996)EDEKEDHK 49.141000000000005 0.037787 4928800.0 13074.0 23848.0 16499.0 19752.0 26747.0 17454.0 21627.0 27248.0 17476.0 19490.0 True False 12887.56236252204 23792.781421216754 15142.515907981777 21204.627970740432 25173.794046625262 16707.533107261246 22746.74023827629 28514.04155371452 15507.668849561573 22858.82053120743 0.5637894722051655 1.0408577900480147 0.6624364493044965 0.9276343869882239 1.101272658064635 0.7309009266008151 0.9950968470670598 1.2473977611743545 0.6784107180153988 1.0 14.480463344883246 -3.9297934627371167 0.6476063413097168 0.9625888237202029 1.0852808873376172e-21 0.19816307382092535 0.18947711425172684 15.85104237743459 2.224162954953074 0.0803763483203465 14.513581563800022 0.00011754564334086776 3.9297934627371167 -0.9625888237202029 DDSLDLS(ph)PQGR ddPTM_PC-9_AZD4547_30min_R2 3 DDSLDLSPQGR 11 0 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 DDS(0.013)LDLS(0.987)PQGR;DDS(0.1)LDLS(0.9)PQGR;DDS(0.488)LDLS(0.512)PQGR 118.76 0.0010321 27533700.0 95732.0 104875.0 135144.0 152687.0 130840.0 130393.0 119872.0 154967.0 102182.0 131026.0 True False 126172.7846507004 138773.7928075964 133351.90225847918 117487.37114063423 112675.1244627964 122239.50509708616 130540.37577716584 131020.41093739818 107583.13191131248 126438.8196212108 0.997895939148219 1.097556851790764 1.0546753177384824 0.929203321358159 0.8911434383866593 0.9667877750147853 1.0324390576267843 1.036235638152215 0.8508710555319422 1.0 16.94807994647033 -5.749390215321059 24.714796754779645 0.9602769506587698 1.054794167660705 0.3328718673857983 0.05947952555828456 232.2991134005532 476478.13011968596 0.016721413426724 0.028676551905385088 1.7807780122794415e-06 5.749390215321059 0.09451721700193527 DDSLDLS(ph)PQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DDSLDLSPQGR 11 0 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 DDS(0.016)LDLS(0.984)PQGR 126.5 0.00040761 11428000.0 70398.0 59931.0 66867.0 74805.0 63247.0 54926.0 68254.0 73351.0 53339.0 46826.0 True False 82314.99097612119 65880.55360981927 68461.3628745096 70613.91837108202 50854.20437238842 52045.58386830315 61788.48700383257 71425.61397180878 54118.98196752597 55315.18312558794 1.4881084419305406 1.1910030824673155 1.237659517804985 1.276573887693 0.9193534487073597 0.9408914682635784 1.1170258057999665 1.2912478986039624 0.9783748133790663 1.0 15.755387910886165 -1.5228787452828296 0.5597260338842014 1.0663438832106442 20.26702633578308 0.5153760335564808 0.12242420753196995 129.4207673697171 1.1490054105189966 0.06366105945743154 2998.548755187983 0.029999999999827855 1.5228787452828296 19.200682452572433 DDSLDLS(ph)PQGR ddPTM_PC-9_Lapatinib_30min_R1 1 DDSLDLSPQGR 11 0 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 DDSLDLS(1)PQGR 106.54 0.0024209 10419000.0 41251.0 47638.0 51373.0 45148.0 45175.0 50491.0 39533.0 39096.0 60713.0 39516.0 True False 40662.75317549307 47527.69713786998 47149.31024551474 48468.3345293129 42517.89531746723 48331.61763026967 41579.825303545425 40912.542886965006 53874.862603766975 46346.287948239755 0.8773680692811009 1.0254909129065448 1.0173265720476214 1.0457867647014811 0.9173959166902831 1.0428368650418598 0.8971554604326114 0.8827577072117785 1.162441804701495 1.0 15.500166172054497 -8.262934079583566 24.999617932213404 1.0812208927029998 0.968811577515489 0.2907286469660445 0.07328724882009881 178.65900359098282 2988007.4158613603 0.058655510223932415 0.018250796160836753 5.458407065279695e-09 8.262934079583566 -0.11240931518751085 DDVGS(ph)PRPR ddPTM_PC-9_AZD4547_30min_R2 1 DDVGSPRPR 9 1 A0A1C7CYW6;A0A1B0GWB1;A0A1B0GTQ2;P0DI83 A0A1C7CYW6 RAB34 Ras-related protein Rab-34, isoform NARR 1 DDVGS(1)PRPR 55.258 0.043253 17468000.0 18787.0 18905.0 28152.0 31789.0 25271.0 27872.0 25647.0 30979.0 18150.0 22804.0 True False 24760.875206124445 25015.67154257556 27778.68608580998 24460.537185154117 21762.557859212247 26129.159433911253 27929.53331517762 26191.907376600517 19109.371946040625 22005.638900997394 1.1252059218786041 1.136784605760378 1.2623439933185001 1.1115576918807595 0.9889536930566406 1.187384722228036 1.269198928548797 1.19023617057596 0.868385236711964 1.0 14.425585638394827 -8.25600309699502 24.79198833715301 0.9341926093274647 1.1590406987343738 0.5502475719769959 0.08128255351979602 285.23213793099274 1300808.3605409598 0.062270192327949246 0.022025137216393997 5.546217578836052e-09 8.25600309699502 0.22484808940690904 DDYPS(ph)SPPK ddPTM_PC-9_Lapatinib_30min_R1 1 DDYPSSPPK 9 0 H3BPC4;H3BQQ9;B0QYN7;P63279 H3BPC4 UBE2I SUMO-conjugating enzyme UBC9 1 DDY(0.001)PS(0.637)S(0.362)PPK 71.34899999999999 0.035218 4383700.0 29648.0 46896.0 38663.0 42367.0 51173.0 43589.0 49137.0 48051.0 37819.0 44743.0 True False 29225.214083222687 46787.415193281624 35484.27738349592 45482.8105121689 48163.104749988954 41724.80008092185 51681.07343081248 50283.62487879977 33559.425968274714 52476.76793370006 0.5569171889577168 0.8915834003419104 0.6761902224681081 0.8667227861600122 0.9177986115844434 0.7951099452930789 0.9848372044579257 0.9582073526770715 0.6395101544873 1.0 15.679391246044807 -4.00658364157554 0.7480969096445416 0.8791778348088514 1.1862709529797746e-19 0.3335376962549399 0.12050247982024492 9.642850710317834 1.7691801147953068 0.04472955270932006 9.32444303451939 9.849549302488238e-05 4.00658364157554 -0.8791778348088514 DDYPSS(ph)PPK ddPTM_PC-9_AZD4547_30min_R2 2 DDYPSSPPK 9 0 H3BPC4;H3BQQ9;B0QYN7;P63279 H3BPC4 UBE2I SUMO-conjugating enzyme UBC9 1 DDYPS(0.028)S(0.972)PPK;DDYPS(0.043)S(0.957)PPK 87.806 0.010606 4733300.0 93492.0 119425.0 89201.0 85842.0 91017.0 98275.0 119699.0 115772.0 106462.0 105493.0 True False 123220.51124559485 158026.79576683883 88018.13645710204 66052.45314567933 78380.86061777995 92129.84871439528 130351.97911231115 97882.09757589981 112089.36397351943 101799.72217956994 1.2104208990692493 1.5523303245178504 0.8646205959368157 0.6488470865290369 0.7699516161696374 0.9050108069242325 1.280474802105809 0.9615163526992773 1.1010773072228923 1.0 16.635374098613646 -5.269484878802562 24.888213304188227 0.9342962880933694 1.3813756183197228 0.48731381578862254 0.18037938610224688 446.03585777744496 1379785.2298047673 0.051498021761565 0.11030706329567147 5.376691532769547e-06 5.269484878802562 0.4470793302263534 DDYPSS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DDYPSSPPK 9 0 H3BPC4;H3BQQ9;B0QYN7;P63279 H3BPC4 UBE2I SUMO-conjugating enzyme UBC9 1 DDY(0.004)PS(0.226)S(0.769)PPK 77.744 0.022612 4234400.0 69724.0 105830.0 62598.0 75739.0 76687.0 45863.0 74919.0 67228.0 48302.0 41212.0 True False 81526.89608822767 116336.10299389575 64090.573724237016 71495.58937915102 61660.73285223566 43457.86354280279 67822.12995341116 65463.336233953945 49008.325371593746 48683.4093659875 1.6746340724687652 2.3896457645214464 1.3164766921400883 1.4685822194922358 1.2665656258518887 0.8926626978012038 1.3931261355083908 1.3446744401531108 1.006674060215537 1.0 15.571142585053185 -5.3688351115326824 5.987252237312711 1.223031794173822 2.0268839787139363 0.6547188974544933 0.23893350206389152 0.12517838484107774 5.8647426236470706 0.0610881543623696 0.1294862877603691 4.277252496560868e-06 5.3688351115326824 0.8038521845401143 DDYPSS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 1 DDYPSSPPK 9 0 H3BPC4;H3BQQ9;B0QYN7;P63279 H3BPC4 UBE2I SUMO-conjugating enzyme UBC9 1 DDYPS(0.205)S(0.795)PPK 101.66 0.0034257 5160300.0 29484.0 47132.0 38394.0 41389.0 48803.0 47762.0 48460.0 47588.0 42745.0 47765.0 True False 29063.552753296593 47022.86874978144 35237.393525125924 44432.88512965652 45932.50349038967 45719.33059865996 50969.021683398954 49799.11220853518 37930.60797519508 56021.11660713819 0.5187963845332088 0.839377570417613 0.6290019845951444 0.793145296286274 0.81991410154322 0.816108877644799 0.9098180252427261 0.8889346593671751 0.6770769715497241 1.0 15.77368311889772 -3.2361310000199874 0.28146003015759696 0.8988364784794751 1.597466507862837e-32 0.44944667101222524 0.10078170089397537 20.35605513682276 0.6655163746111304 0.11204117114180767 7.408022606591084 0.0005805892629193816 3.2361310000199874 -0.8988364784794751 DDYSRDDYR ddPTM_PC-9_AZD4547_30min_R2 1 DDYSRDDYR 9 1 E7EX17;P23588-2;P23588;F8VX11 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 90.601 0.01095 21535000.0 34443.0 32189.0 59010.0 91486.0 77295.0 62325.0 43848.0 53838.0 42895.0 58235.0 False True 45395.157541094624 42593.46475979713 58227.48884355092 70395.31614461001 66563.92345881896 58427.807897478466 47750.38705516855 45518.57417416373 45162.342128121876 56196.2103753545 0.8077974873729776 0.757941940840854 1.036146182360497 1.2526701653797405 1.184491320930981 1.039710818705004 0.8497083119346787 0.8099936609627049 0.8036545850061153 1.0 15.778185224283495 -7.265381009287818 23.40706100709595 0.8500052571512111 1.0212510617643882 0.18587918576472284 0.1489653517537539 251.59968779241495 1494086.4387521225 0.06967186832137781 0.04902892725610374 5.427739435502768e-08 7.265381009287818 0.17124580461317707 DDYVHEFCR ddPTM_PC-9_AZD4547_30min_R2 2 DDYVHEFCR 9 0 Q13564-3;Q13564-2;Q13564;Q13564-4 Q13564-3 NAE1 NEDD8-activating enzyme E1 regulatory subunit 0 ; 96.665 0.0031961 0.0 47581.0 48177.0 50383.0 54532.0 51084.0 57558.0 50393.0 63550.0 49662.0 51774.0 False True 62710.76825371839 63749.27309741671 49714.88850033259 41960.48991100141 43991.8683740255 53958.889161059975 54877.87937582351 53729.80773372166 52287.03193301759 49961.40801877913 1.2551841659495888 1.2759703063903862 0.9950658012209368 0.8398580339295002 0.8805169853797986 1.0800113787981775 1.0984053803126688 1.0754262112374033 1.0465484061891195 1.0 15.608526515284073 -5.26205493339973 24.957041451304462 1.0007755151371065 1.265577258622765 0.6343230126639152 0.08005222231903682 36.071540365454624 1462565.7066222501 0.024246645708776892 0.05598194449891079 5.469467758620822e-06 5.26205493339973 0.26480174348565844 DDYVHEFCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DDYVHEFCR 9 0 Q13564-3;Q13564-2;Q13564;Q13564-4 Q13564-3 NAE1 NEDD8-activating enzyme E1 regulatory subunit 0 ; 72.243 0.027537 3754300.0 49921.0 50683.0 47212.0 52893.0 58935.0 44271.0 55979.0 49394.0 44167.0 39494.0 False True 58371.639315306355 55714.47328772202 48337.713132507044 49929.5766914197 47387.10981843743 41949.350825358626 50676.26386713662 48097.459837269 44812.8588192452 46653.949565668 1.2511617957048857 1.1942070029741176 1.0360904828533124 1.0702111430274746 1.015714859290476 0.8991596899274863 1.0862159439643366 1.0309407946173814 0.9605373014811669 1.0 15.509711599481973 -5.088294765622924 1.1970233286450014 1.0034673689261167 1.31026861045336 0.7501747850754537 0.04942325301063643 0.47364360981514864 0.8316412806008303 0.015887462415705045 0.15851421927164894 8.160283262223508e-06 5.088294765622924 0.3068012415272434 DDYVHEFCR ddPTM_PC-9_Lapatinib_30min_R1 1 DDYVHEFCR 9 0 Q13564-3;Q13564-2;Q13564;Q13564-4 Q13564-3 NAE1 NEDD8-activating enzyme E1 regulatory subunit 0 79.97399999999999 0.016252000000000003 2368000.0 12703.0 20744.0 24452.0 20086.0 25941.0 21147.0 21752.0 22751.0 24771.0 21293.0 False True 12521.852890555108 20695.968542507548 22441.650947449565 21563.191444931777 24415.20138196829 20242.592106064716 22878.212126646587 23808.094516608882 21981.029129805982 24973.466678860947 0.5014062745703768 0.8287182876386908 0.8986197725782915 0.8634440593377517 0.9776456627319103 0.810563962399312 0.9161007729059935 0.9533355870357195 0.8801753241736381 1.0 14.60810848168279 -4.652596322501543 2.087727352634543 0.9087878854350496 0.2798300295529287 0.8440689772294172 0.05285089611780432 0.387390307317041 1.3960573889503367 0.013337067419110296 0.5225666417458649 2.2253774219133575e-05 4.652596322501543 -0.6289578558821209 DEALQNIS(ph)ADDLPDSASQAAHPQDSAFSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DEALQNISADDLPDSASQAAHPQDSAFSYR 30 0 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;F8W9S7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 DEALQNIS(0.996)ADDLPDS(0.003)ASQAAHPQDSAFSYR 77.321 7.528899999999999e-05 0.0 2605.7 4246.1 3912.2 3376.6 4036.9 3535.4 4531.0 2879.8 3899.2 3556.8 True False 3046.793545079103 4667.624746502702 4005.4816851011233 3187.4200490849034 3245.898424129124 3349.9974002839986 4101.790878400758 2804.2083014003183 3956.2184234383303 4201.619684386694 0.7251473893272756 1.1109108146669469 0.9533184785823373 0.7586169830956911 0.7725350383784021 0.7973109543285554 0.9762403993019878 0.66741126328516 0.9415936521193768 1.0 12.036729864978426 -5.7379729629586205 24.45384905018471 0.8314426064120856 0.947904200337115 0.06894851815382641 0.13212768595519764 357.03533676298593 372054.76696365426 0.03389798968003774 0.05866404605186195 1.8282140282260282e-06 5.7379729629586205 0.11646159392502942 DEALQNISADDLPDS(ph)ASQAAHPQDSAFSYR ddPTM_PC-9_AZD4547_30min_R2 2 DEALQNISADDLPDSASQAAHPQDSAFSYR 30 0 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;F8W9S7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 DEALQNIS(0.346)ADDLPDS(0.593)AS(0.061)QAAHPQDSAFSYR;DEALQNISADDLPDS(0.496)AS(0.496)QAAHPQDS(0.002)AFS(0.003)Y(0.003)R 79.016 7.790899999999999e-07 9193200.0 6868.6 8084.1 12751.3 11678.3 9880.0 10535.4 11946.3 13381.400000000001 10833.099999999999 11455.099999999999 True False 9052.67192424476 10697.127231808254 12582.209430448582 8986.048362936393 8508.332541213915 9876.619772532604 13009.49755695038 11313.61210398148 11405.715549788014 11054.060435661078 0.8189453981127409 0.9677102178036465 1.1382432277878272 0.8129183312538123 0.7697020104725962 0.8934834244862658 1.1768976325641338 1.0234802107181424 1.0318123024723544 1.0 13.432288784855755 -7.2317518077742475 24.34229216414238 1.060004233035152 0.9041627733874434 0.3477310701336688 0.10583317340314743 638.3958321363789 523452.486742079 0.04365340208270686 0.03380795286658159 5.864732286649933e-08 7.2317518077742475 -0.15584145964770857 DEALQNISADDLPDS(ph)ASQAAHPQDSAFSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DEALQNISADDLPDSASQAAHPQDSAFSYR 30 0 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;F8W9S7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 DEALQNISADDLPDS(0.729)AS(0.27)QAAHPQDSAFSYR 86.07600000000001 6.310899999999999e-09 4840800.0 4975.0 5671.0 6189.5 6547.8 6762.1 5034.2 5522.7 5678.5 6439.3 5118.7 True False 5817.169239271033 6233.97940166667 6337.081153809463 6180.947994254022 5437.115047141013 4770.197689797392 4999.549875114513 5529.445391868086 6533.462580541249 6046.679790393094 0.962043541401563 1.0309756126942848 1.048026582105068 1.0222052776921067 0.899190173056534 0.7888953698815399 0.8268256379406347 0.9144597669374216 1.0805041455844167 1.0 12.561927465926452 -6.26118804842833 23.510352068748503 0.9029902972710355 1.0191968111956968 0.24985335420996468 0.08008257634080815 12.800199915479196 1197317.156494323 0.025724547963922883 0.031167373688876093 5.480396137513807e-07 6.26118804842833 0.1162065139246613 DEALQNISADDLPDSAS(ph)QAAHPQDSAFSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DEALQNISADDLPDSASQAAHPQDSAFSYR 30 0 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;F8W9S7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 DEALQNISADDLPDS(0.256)AS(0.744)QAAHPQDSAFSYR 110.07 1.4364e-15 4512100.0 12037.0 13586.0 13908.0 13661.0 13735.0 11276.0 12930.0 8839.1 11800.0 8356.0 True False 14074.626358413161 14934.728293253978 14239.619466383721 12895.618459559579 11043.725347522479 10684.666709736479 11705.176794906596 8607.082990800594 11972.552676593228 9870.876653940393 1.4258739980095545 1.5130093118215722 1.4425891403170714 1.30643091912325 1.1188191013524509 1.0824435442085305 1.185829506868973 0.8719674343579908 1.2129168559525925 1.0 13.268962503905906 -6.092552266779029 1.6365950951485237 1.0661270587218823 1.477664917340802 0.7863746415314791 0.09068917167667172 0.15767364981404067 0.8439882619355434 0.02982772470131031 0.046316730700105974 8.080676733613011e-07 6.092552266779029 0.4115378586189198 DEAS(ph)SVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DEASSVTR 8 0 E7ERS3;Q86VM9 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 DEAS(0.5)S(0.5)VTR 70.399 0.038245 9631700.0 27526.0 48744.0 39708.0 28693.0 33627.0 24264.0 31208.0 24990.0 23413.0 32047.0 True False 32185.608136718474 53582.98218212659 40654.78931342858 27085.424233961116 27038.030743439274 22991.553125669212 28251.752313646193 24334.03897909367 23755.37083195569 37856.86741608759 0.8501920611381842 1.4154098275800828 1.0739079086124275 0.7154692419809395 0.7142173293490534 0.6073284636303203 0.7462781323961416 0.642790612113688 0.627504927200095 1.0 15.208267415254173 -5.722204917274458 4.363415851322138 0.7009756594954337 1.1563396102834482 0.5402855728568876 0.1646636107932875 0.13003312911423315 5.386779498587339 0.04278373334326296 0.07383154967760638 1.8958111916116933e-06 5.722204917274458 0.4553639507880145 DEASS(ph)VTR ddPTM_PC-9_Lapatinib_30min_R1 1 DEASSVTR 8 0 E7ERS3;Q86VM9 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 DEAS(0.129)S(0.871)VTR 102.62 0.0042228000000000005 12080000.0 47048.0 50428.0 42850.0 43389.0 60515.0 53265.0 42169.0 51818.0 44689.0 47667.0 True False 46377.08689245348 50311.2370642871 39327.03840578335 46579.97180146094 56955.62667706762 50986.98011677954 44352.30448549834 54225.65345090937 39655.65422396753 55906.17743771494 0.8295520999288886 0.8999226806436345 0.7034471002707634 0.833181124811398 1.018771615006622 0.912009771613953 0.7933345923160501 0.9699402809523537 0.7093250878786675 1.0 15.770720084198548 -6.018740623408581 24.836177650657188 0.8971537030191771 0.8112763744067195 0.1512930830048138 0.09836878801053471 1368.9416815343006 1814202.6054943309 0.02819441262169427 0.03706550167555034 9.577659134428317e-07 6.018740623408581 -0.08587732861245756 DEDDADYKPK ddPTM_PC-9_Lapatinib_30min_R1 1 DEDDADYKPK 10 1 P11387 P11387 TOP1 DNA topoisomerase 1 0 77.192 0.028651999999999997 7231400.0 64321.0 59443.0 53431.0 46680.0 40757.0 50971.0 52198.0 53537.0 46716.0 32737.0 False True 63403.77074497319 59305.36338566706 49038.1094296245 50113.00291991511 38359.75339134502 48791.08914920433 54900.5570332245 56024.52446642739 41454.35213871125 38395.54683068945 1.6513313646647882 1.5445896277290276 1.2771822119337153 1.3051774764634927 0.9990677710750607 1.2707486460436541 1.4298678249151187 1.4591412049286705 1.0796656268892335 1.0 15.228651374406526 -5.180069939035915 2.254042964114139 1.2415700659488569 1.6553243968516316 0.4927901465123603 0.1520700832430674 0.31727290432519895 2.9082758806294664 0.04313967240553536 0.18319207266356988 6.6058705811729926e-06 5.180069939035915 0.4137543309027747 DEDDDEEEEEEGGSWGR ddPTM_PC-9_Lapatinib_30min_R1 1 DEDDDEEEEEEGGSWGR 17 0 Q5VYD6;O00165-4;O00165-6;O00165-3;O00165;O00165-2 Q5VYD6 HAX1 HCLS1-associated protein X-1 0 265.77 1.2467e-68 2036100.0 4380.8 4554.3 2032.0 3888.5 3097.0 3312.4 4212.5 2986.3 4016.7 3023.3 False True 4318.328988659669 4543.754798165359 1864.936803746831 4174.473261655738 2914.840548936268 3170.7363735815375 4430.602638079202 3125.0544000241375 3564.2969482738586 3545.873376705972 1.2178463610765733 1.2814204895230619 0.5259456854827994 1.1772764614436737 0.8220374049690635 0.8942046251316149 1.2495095474038391 0.8813214878324942 1.0051957781935805 1.0 11.791925303115256 DEDMLY(ph)SPELAQR ddPTM_PC-9_Lapatinib_30min_R1 1 DEDMLYSPELAQR 13 0 Q9Y2W2 Q9Y2W2 WBP11 WW domain-binding protein 11 1 DEDMLY(0.5)S(0.5)PELAQR 75.509 0.019162000000000002 9235300.0 39908.0 39902.0 48214.0 48453.0 52423.0 42438.0 42012.0 41695.0 43126.0 44340.0 True False 39338.9046017691 39809.60937057157 44250.031031422106 52016.395254469746 49339.58220758348 40623.02566780983 44187.17579370526 43632.301915080985 38268.695743087235 52004.10992066376 0.7564576080964294 0.7655089074941225 0.8508948830953728 1.0002362377478382 0.9487631320458091 0.7811502923477271 0.8496862240526022 0.8390164158495433 0.7358782950322398 1.0 15.666338024492662 -5.295863300217632 4.4951004245068304 0.873588033268266 0.7592640816478615 0.24158301139846483 0.08193759550951574 0.2965275172868552 14.498179337668464 0.022699702165933915 0.0533811081207 5.05983901891144e-06 5.295863300217632 -0.11432395162040443 DEDMLYS(ph)PELAQR ddPTM_PC-9_AZD4547_30min_R2 2 DEDMLYSPELAQR 13 0 Q9Y2W2 Q9Y2W2 WBP11 WW domain-binding protein 11 1 DEDMLYS(1)PELAQR;DEDMLYS(1)PELAQR 139.19 4.6313e-05 29137000.0 46596.0 55573.0 66274.0 66999.0 78198.0 74279.0 57499.0 82106.0 57682.0 62388.0 True False 61412.55874299113 73535.88546075388 65395.16345733766 51553.41567423128 67341.55749573348 69634.32238775461 62616.299609677415 69418.40430818165 60730.952759863096 60203.8151094293 1.0200775255083878 1.2214489285619454 1.0862295576862084 0.8563147631180076 1.118559635686381 1.156643017742048 1.0400719538431753 1.153056565966849 1.0087558844813347 1.0 15.877567292864248 -8.452867463407154 13.109994035069105 1.0000007247044636 1.0812121025564747 0.09810297761509756 0.09377985149590354 3.413020646587978 634.8829807196345 0.09234079827856574 0.023843481793171674 3.524784228616464e-09 8.452867463407154 0.08121137785201116 DEDMLYS(ph)PELAQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DEDMLYSPELAQR 13 0 Q9Y2W2 Q9Y2W2 WBP11 WW domain-binding protein 11 1 DEDMLYS(1)PELAQR 122.66 0.00015711 9736500.0 26287.0 28103.0 32255.0 26564.0 38801.0 31149.0 35306.0 24194.0 29292.0 21045.0 True False 30736.86990808396 30892.88011374329 33024.081527768685 25075.70520164999 31198.222585309068 29515.49160531941 31961.560086695474 23558.933135661962 29720.340084980395 24860.291907871677 1.2363841109344154 1.2426595885610447 1.3283867160591165 1.008664954320593 1.254941925095842 1.1872544262432303 1.2856470151332082 0.9476531177899139 1.1954944131436305 1.0 14.601555616067216 -8.44836797577968 0.17511892260050008 0.9064026381646163 1.3193816138821424 0.28581650828169847 0.10711713384061941 6.1308444983752715 0.8588439592110799 0.9687053383702026 0.6841367480607432 3.5614924188266744e-09 8.44836797577968 0.41297897571752606 DEDMLYS(ph)PELAQR ddPTM_PC-9_Lapatinib_30min_R1 3 DEDMLYSPELAQR 13 0 Q9Y2W2 Q9Y2W2 WBP11 WW domain-binding protein 11 1 DEDMLYS(1)PELAQR;DEDMLYS(1)PELAQR;DEDMLYS(1)PELAQR 136.01 4.7078999999999994e-05 17111400.0 61089.7 60148.7 73870.20000000001 64938.6 67123.5 60841.3 63559.100000000006 60661.5 66845.1 64125.2 True False 60218.54967552103 60009.42938067508 67796.87730321827 69714.40127281922 63175.427699878426 58239.259426997436 66849.87920093529 63480.05474569337 59316.300927891236 75209.15537854194 0.8006811055439947 0.7979005890790323 0.9014444712479981 0.9269403561565532 0.8399965055039446 0.7743639605293824 0.8888529443585316 0.8440469039465504 0.788684577420675 1.0 16.198620674633773 -11.320278877118115 3.995386763764893 1.0243451268600587 0.8430082344758629 0.4874463501157742 0.049051669865855144 0.012391217336878342 0.0006283390706756624 0.055325732360260546 0.012194749664820955 4.7832284426967104e-12 11.320278877118115 -0.1813368923841958 DEEDTS(ph)FESLSK ddPTM_PC-9_AZD4547_30min_R2 1 DEEDTSFESLSK 12 0 H7C3L4;E7EQA9;Q92844 H7C3L4 TANK TRAF family member-associated NF-kappa-B activator 1 DEEDT(0.039)S(0.945)FES(0.016)LSK 99.161 0.0099864 0.0 19217.0 20508.0 19830.0 19196.0 22379.0 25943.0 22115.0 29927.0 17316.0 23239.0 True False 25327.60626156882 27136.809944202058 19567.041243308173 14770.658775243579 19272.06213965853 24320.780108853327 24083.192157568246 25302.469804045453 18231.288408685356 22425.4096834011 1.1294155433118298 1.2100920485875561 0.8725388530043827 0.6586572545952891 0.8593850641633262 1.0845188762306157 1.073924289347285 1.1282946515253143 0.8129745973907375 1.0 14.452846721118165 -5.257582738659681 24.965004341949708 0.9384164590774631 1.1697538137242511 0.31749504211810964 0.13689251469623132 423.2428327183824 2739728.8979735174 0.039524800159160246 0.09672773796764322 5.526081189928252e-06 5.257582738659681 0.23133735464678806 DEEPSGWEEPS(ph)PQSISR ddPTM_PC-9_AZD4547_30min_R2 4 DEEPSGWEEPSPQSISR 17 0 Q9UPQ9-1;Q9UPQ9;H0Y720 Q9UPQ9-1 TNRC6B Trinucleotide repeat-containing gene 6B protein 1 DEEPSGWEEPS(0.886)PQS(0.113)IS(0.001)R;DEEPSGWEEPS(1)PQSISR;DEEPSGWEEPS(0.999)PQS(0.001)ISR;DEEPSGWEEPS(0.999)PQS(0.001)ISR 250.08 1.0290999999999998e-47 21170200.0 41521.9 46023.5 44840.2 50246.6 51662.1 58897.1 49691.6 56063.3 57399.7 48717.899999999994 True False 54725.00049082762 60899.69633640447 44245.589649933776 38663.02267223142 44489.70916775787 55214.255026371044 54114.05613461533 47400.00519147061 60433.73095818991 47012.30114957468 1.1640570478929366 1.2953991795178361 0.9411492006988061 0.822402259128326 0.9463418739322945 1.1744639950871787 1.1510616330488834 1.0082468637444997 1.2854876166540647 1.0 15.520750678584152 -6.775704536480547 24.982361620546122 1.1260680442448479 1.0314999456639096 0.08985116952356975 0.14300617061528872 676.6334073635338 1184971.4586568165 0.05513678995244448 0.04885450161013963 1.676082777448652e-07 6.775704536480547 -0.09456809858093829 DEEPSGWEEPS(ph)PQSISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DEEPSGWEEPSPQSISR 17 0 Q9UPQ9-1;Q9UPQ9;H0Y720 Q9UPQ9-1 TNRC6B Trinucleotide repeat-containing gene 6B protein 1 DEEPSGWEEPS(0.987)PQS(0.012)IS(0.001)R;DEEPSGWEEPS(0.995)PQS(0.005)ISR;DEEPSGWEEPS(0.853)PQS(0.146)ISR 137.4 5.942e-05 13705500.0 42585.4 46442.0 42828.2 54816.1 50195.1 50578.4 60333.5 47853.8 52939.5 45762.5 True False 49794.26712001062 51052.45483551458 43849.386714853 51744.931633193984 40359.73048354027 47925.97966581555 54618.27410328673 46597.68845529225 53713.64003580567 54058.87899424935 0.9211117220042171 0.9443861172360865 0.8111412506263325 0.9571957945835037 0.7465883724269169 0.8865514889961701 1.0103478858504795 0.8619802948605204 0.9936136493233534 1.0 15.722243974918069 -8.274017704679043 23.119491713395938 0.996806927962416 0.8924706579823771 0.2567348494543391 0.07105006450622005 445.4958649575422 818817.5327082836 0.06610677774551507 0.017642144886977934 5.320865675016101e-09 8.274017704679043 -0.10433626998003886 DEEPSGWEEPS(ph)PQSISR ddPTM_PC-9_Lapatinib_30min_R1 3 DEEPSGWEEPSPQSISR 17 0 Q9UPQ9-1;Q9UPQ9;H0Y720 Q9UPQ9-1 TNRC6B Trinucleotide repeat-containing gene 6B protein 1 DEEPSGWEEPS(0.984)PQS(0.016)ISR;DEEPSGWEEPS(0.999)PQSISR;DEEPS(0.016)GWEEPS(0.983)PQS(0.001)ISR 270.78 6.746199999999998e-70 15068600.0 40094.0 43321.0 37661.8 37958.0 50883.0 47500.0 42586.0 46995.0 47877.0 42124.0 True False 39522.25220766087 43220.6928861343 34565.392182752184 40749.55794417602 47890.16197982702 45468.53572790817 44790.89470510169 49178.559263682204 42484.58809283928 49405.077273298164 0.7999633719634189 0.87482289820228 0.6996323878119639 0.8248050644422295 0.9693368500348464 0.9203211134836629 0.9066050935884217 0.9954150864219297 0.8599235227955168 1.0 15.592371692221935 -6.160537274430137 5.050276822138502 0.9385661631801534 0.7947106669164894 0.6103817762243641 0.055896465293627726 0.1539636226402965 6.116831981356165 0.016104245680513943 0.021002269412369153 6.909756221170675e-07 6.160537274430137 -0.143855496263664 DEEQSEADAGS(ph)GPPTPGPTTLGPK ddPTM_PC-9_Lapatinib_30min_R1 1 DEEQSEADAGSGPPTPGPTTLGPK 24 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2;A0A087X0E3 A0A0A0MS59 SRCAP Helicase SRCAP 1 DEEQS(0.02)EADAGS(0.967)GPPT(0.012)PGPTTLGPK 65.801 0.0059243 0.0 8167.5 8133.2 9523.1 8094.1 11107.0 10624.0 8582.6 5848.7 8301.9 6924.1 True False 8051.029952263934 8114.36807510232 8740.147478229064 8689.367115126064 10453.708097202183 10169.636285753608 9026.965033015673 6120.451953729086 7366.852599117367 8120.9214592166945 0.9913936482080568 0.9991930245665734 1.076250709001697 1.0699976792983539 1.2872563969126847 1.2522761532451174 1.1115690600320582 0.7536647145851643 0.9071449140486995 1.0 12.987427720104385 -7.741464131793514 24.507434461216835 0.8728036736940773 1.117261010822841 0.4856800307764225 0.10602384657245778 157.08364758022643 192724.82436753623 0.05494537491633515 0.031664942319380045 1.813576452235082e-08 7.741464131793514 0.2444573371287636 DEEVHAGLGELLR ddPTM_PC-9_AZD4547_30min_R2 2 DEEVHAGLGELLR 13 0 P50454;E9PQ34;E9PJH8;E9PIG2;E9PRS3;E9PNX1;E9PK86;E9PMI5;E9PR70;E9PPV6 P50454 SERPINH1 Serpin H1 0 ; 89.44 0.0051242 6369200.0 35892.0 43157.0 47905.0 43697.0 36619.0 46367.0 45588.0 61051.0 42832.0 42059.0 False True 47304.90940002228 57106.65626886717 47269.74839942906 33623.33176192011 31535.08393995067 43467.66416016659 49645.24368434191 51616.97076241445 45096.01207673891 40586.527211763256 1.1655323243894546 1.407034801743665 1.1646660024100015 0.8284357906870882 0.7769840414138909 1.0709875208926052 1.223195160928998 1.2717759884480637 1.1111079260722918 1.0 15.308713280592471 -5.522537537454466 24.997301073516034 1.0455193698458598 1.2861753044174702 0.2920603967772636 0.15433129699956952 16.139656770026196 1182410.3838136746 0.04784781099652852 0.08406470415585571 3.002357906295503e-06 5.522537537454466 0.24065593457161039 DEEVHAGLGELLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DEEVHAGLGELLR 13 0 P50454;E9PQ34;E9PJH8;E9PIG2;E9PRS3;E9PNX1;E9PK86;E9PMI5;E9PR70;E9PPV6 P50454 SERPINH1 Serpin H1 0 ;; 100.22 0.0030604 3658700.0 60851.6 86883.0 66627.0 53651.2 63594.0 47542.0 65757.0 37859.1 37605.1 45591.0 False True 71152.57400611552 95508.1700502565 68215.6403643047 50645.297203537266 51133.212213348736 45048.81382709223 59528.02092054704 36865.33874003223 38155.00344564033 53856.287401842565 1.3211563113368487 1.7733894157544348 1.2666235207659498 0.9403785453247666 0.9494381191154914 0.8364634103157841 1.1053123746979712 0.6845131834834008 0.7084595928596249 1.0 15.716827160232702 -5.626769978900501 2.8334202221203912 0.8801683576001664 1.5494015636738558 0.7416497042006308 0.15801971136060328 0.1218364439500525 1.9585536681484375 0.04443571551348539 0.08786015407797546 2.361728775460137e-06 5.626769978900501 0.6692332060736894 DEEVHAGLGELLR ddPTM_PC-9_Lapatinib_30min_R1 2 DEEVHAGLGELLR 13 0 P50454;E9PQ34;E9PJH8;E9PIG2;E9PRS3;E9PNX1;E9PK86;E9PMI5;E9PR70;E9PPV6 P50454 SERPINH1 Serpin H1 0 ; 106.79 0.00090644 4918700.0 47024.0 53691.0 45732.0 35760.0 48288.0 46093.0 49214.0 46764.0 44621.0 41089.0 False True 46353.42913685453 53566.681788265225 41972.09149062503 38389.90969186298 45447.794777860676 44121.70983803093 51762.06011404861 48936.82616037525 39595.31310003929 48191.17890234902 0.96186543248468 1.111545370093741 0.870949672670887 0.7966169445585344 0.9430728986720301 0.9155557270644041 1.0740982331836155 1.0154726917873735 0.8216298916503424 1.0 15.556481473753916 -9.287750579401205 16.590144664575206 0.9999297638438573 0.9488157536477566 0.02678288459466538 0.09660907384858977 0.0 0.0 0.09818004384118423 0.023812158299116194 5.155246316400905e-10 9.287750579401205 -0.051114010196100734 DEFEFLEK ddPTM_PC-9_Lapatinib_30min_R1 2 DEFEFLEK 8 0 A0A3B3IUA7;Q14258 A0A3B3IUA7 TRIM25 E3 ubiquitin/ISG15 ligase TRIM25 0 ; 121.05 0.002852 0.0 12428.0 13459.9 8001.900000000001 8822.9 11330.4 11729.9 8089.7 8463.8 12280.5 9346.7 False True 12250.774440983925 13428.734428523798 7344.014670227253 9471.765498331599 10663.968148423482 11228.239520732413 8508.5450827939 8857.059046620994 10897.340770602019 10962.26464130511 1.1175404756079135 1.2249963732790383 0.6699359038054489 0.864033647084435 0.9727887893020147 1.0242627676059861 0.7761667284271033 0.8079588786105532 0.9940775129202353 1.0 13.420258248037749 -5.23932718257961 24.9840912960768 0.8847458299662236 1.171268482834667 0.5103680965366688 0.11067287954502203 636.2574168662302 718890.9542011173 0.028538140872798858 0.07537681839792734 5.763321109379008e-06 5.23932718257961 0.28652265286844325 DEFEGLFK ddPTM_PC-9_AZD4547_30min_R2 2 DEFEGLFK 8 0 P22314;P22314-2;Q5JRR6 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 ; 111.04 0.017289 2685200.0 13085.2 15466.8 19872.9 25512.0 21437.9 20608.3 17757.199999999997 19520.7 20051.0 16946.6 False True 17246.021410932015 20466.140630241083 19609.372361277816 19630.602556470847 18461.617630090077 19319.659743178563 19337.556399745456 16504.224356060746 21110.85492507219 16353.304692143583 1.0545893772295032 1.2514987652662877 1.1991076256714341 1.2004058461591396 1.128922745441132 1.1813917802473324 1.1824861557820519 1.0092286951633493 1.290922863756964 1.0 13.997294585988875 -13.629102530780555 0.36682976211572 1.2434978724017022e-15 1.1706817184945129 0.266084466895837 0.0808280883094332 329.45563384127996 4.9320723908736985 255.19537260349418 0.05448428007799966 2.349078171268976e-14 13.629102530780555 1.1706817184945115 DEFEGLFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DEFEGLFK 8 0 P22314;P22314-2;Q5JRR6 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 ; 117.4 0.016349000000000002 3272800.0 18633.6 20101.7 17529.8 25568.0 23281.0 20159.1 22497.0 20610.7 21156.9 17913.699999999997 False True 21787.900449624278 22097.263928492837 17947.77691413672 24135.507852574417 18719.255174056863 19101.921307932676 20365.921295824723 20069.69096384178 21466.279637577558 21161.31200522881 1.029610094319324 1.0442293900790631 0.8481410278201065 1.1405487451161207 0.884598042381846 0.9026813320087491 0.9624129775503735 0.9484143024252324 1.014411565420584 1.0 14.369141457131743 DEFEGLFK ddPTM_PC-9_Lapatinib_30min_R1 2 DEFEGLFK 8 0 P22314;P22314-2;Q5JRR6 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 ; 119.27 0.015972 7907700.0 29619.0 27224.0 32824.0 30790.0 28626.0 24630.0 30847.0 25743.0 24583.0 24920.0 False True 29196.62762854063 27160.964500637587 30125.33742430414 33054.399312429 26942.2749608814 23576.632315334264 32444.10672446982 26939.1137594419 21814.20366953377 29227.388796187224 0.998947522549445 0.9292983608642039 1.0307228481606285 1.1309391866282976 0.9218160113022508 0.8066622878883346 1.11005834119202 0.921707852429026 0.7463617027731017 1.0 14.835033322649357 -6.46901510246286 24.954815305259633 0.91747847494631 1.017656327614644 0.19747040347441946 0.10326507707357195 570.8974562776314 264494.1543605011 0.03287057412956156 0.037271508009790615 3.396134624268038e-07 6.46901510246286 0.10017785266833401 DEGNYLDDALVR ddPTM_PC-9_AZD4547_30min_R2 2 DEGNYLDDALVR 12 0 P09525-2;P09525;Q6P452 P09525-2 ANXA4 Annexin A4;Annexin 0 ; 126.12 0.0026203000000000003 0.0 7016.1 9386.4 11361.8 13934.3 10153.7 13950.5 12238.7 13180.5 9888.9 9833.099999999999 False True 9247.07385605417 12420.370238943728 11211.13510833176 10721.962417788944 8744.034020619814 13078.173029663423 13327.920590496524 11143.756582758739 10411.607065410528 9488.846161962703 0.9745203682532331 1.3089442095428236 1.1815066781536707 1.1299542889386647 0.9215065637454881 1.3782680008122603 1.404588119883665 1.1744058647962872 1.0972469031215655 1.0 13.212016951716723 -6.779710294555431 24.99923832259003 1.2339074544408544 1.120538864301287 0.09850103497578411 0.15071123882726759 577.3576634820508 789965.9443979571 0.05443222930758044 0.048091214292254464 1.6606943397896093e-07 6.779710294555431 -0.11336859013956735 DEGNYLDDALVR ddPTM_PC-9_Lapatinib_30min_R1 3 DEGNYLDDALVR 12 0 P09525-2;P09525;Q6P452 P09525-2 ANXA4 Annexin A4;Annexin 0 ;; 191.33 0.00051873 14456900.0 34558.6 34100.8 37939.8 30707.5 30887.9 31050.6 34570.2 32652.0 27167.4 33557.9 False True 34065.78802672894 34021.84169274689 34820.53609586323 32965.83198721706 29071.134449947895 29722.6382204839 36360.07580271228 34169.13112198643 24107.521326595277 39358.338301908945 0.8655291228358767 0.86441255298364 0.8847054423071102 0.8375819053727216 0.7386270788911303 0.7551802109247662 0.9238214155232451 0.8681548204571728 0.612513697648308 1.0 15.264381691329197 -5.996204891330947 15.493127875657787 0.8099210143267165 0.8692234827495192 0.055155028881061496 0.09990996575681672 3.0708184664427693 12471.98936470788 0.027802066310778466 0.04052912987986438 1.0087768533284476e-06 5.996204891330947 0.059302468422802734 DEHLLK ddPTM_PC-9_AZD4547_30min_R2 1 DEHLLK 6 0 O00629;O00505 O00629;O00505 KPNA4;KPNA3 Importin subunit alpha-3;Importin subunit alpha-4 0 79.027 0.045221 3534900.0 75046.0 75416.0 92707.0 103590.0 99371.0 97449.0 80428.0 91462.0 87237.0 87457.0 False True 98909.06694622974 99792.74715973977 91477.64460632218 79708.92594954591 85575.05191831682 91355.49862497179 87585.93619031852 77328.64948767361 91848.1697221348 84395.1570498391 1.1719756251868758 1.1824463707177855 1.0839205447807931 0.9444727486255431 1.0139805992396098 1.082473234465602 1.037807609488719 0.9162688025096938 1.0883109047109703 1.0 16.36487259292924 -5.454136277278612 3.7405736766758984 1.0122854595631325 1.1751122524633009 0.6256247822713576 0.05082954571584521 0.14628627785012022 3.940685618412141 0.013828957023115162 0.030198840414584267 3.5145014167327733e-06 5.454136277278612 0.16282679290016833 DEHLLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DEHLLK 6 0 O00629;O00505 O00629;O00505 KPNA4;KPNA3 Importin subunit alpha-3;Importin subunit alpha-4 0 79.027 0.045221 3132300.0 53043.0 63572.0 63436.0 73506.0 73126.0 61632.0 68829.0 56784.0 55382.0 53960.0 False True 62022.13225299565 69883.0080272886 64948.55482236973 69387.6971296674 58797.48523938329 58399.9094230648 62309.01884119306 55293.48016762127 56191.85697754965 63742.52085287504 0.9730103457337335 1.0963326691861859 1.0189203996540763 1.0885621748443566 0.9224217124248122 0.9161844972817816 0.9775110555324497 0.8674504777626364 0.8815443165049407 1.0 15.959968454674428 -6.274201376841576 24.171069284746068 0.9228240980577601 1.0461235580665311 0.5737445496881624 0.04916180916354009 332.10869839258964 629008.328948039 0.014713629625281891 0.016795530050577066 5.318615846119439e-07 6.274201376841576 0.12329946000877101 DEILEWESR ddPTM_PC-9_Lapatinib_30min_R1 2 DEILEWESR 9 0 H0YK42;Q13596-2;Q13596;Q13596-3 H0YK42 SNX1 Sorting nexin-1 0 ; 107.69 0.011018 738440.0 10297.2 13090.2 13158.6 11008.5 12516.400000000001 12908.5 15938.2 16498.0 14730.3 11609.599999999999 False True 10150.360039724786 13059.890446159485 12076.75070166489 11818.101813279465 11780.209960189195 12356.433546183207 16763.40200978846 17264.55730891009 13071.218497064352 13616.303891180378 0.7454563382871786 0.9591362348058862 0.8869331059427445 0.8679375774606755 0.8651547478915723 0.9074733969610344 1.2311271945572937 1.2679327258620292 0.959968182373699 1.0 13.733047520379152 -7.166963630648206 5.865732538459047 1.1362151840410686 0.8735895629780637 0.5825385509034874 0.10024138175353375 0.1543721628727763 7.783744234197172 0.03785460373894389 0.029164288826935662 6.808263711082821e-08 7.166963630648206 -0.2626256210630049 DEILPT(ph)TPISEQK ddPTM_PC-9_AZD4547_30min_R2 4 DEILPTTPISEQK 13 0 P23396;P23396-2;E9PL09;E9PPU1;H0YEU2;E9PSF4 P23396 RPS3 40S ribosomal protein S3 1 DEILPT(0.5)T(0.5)PISEQK;DEILPT(0.657)T(0.339)PIS(0.004)EQK;DEILPT(0.58)T(0.344)PIS(0.076)EQK;DEILPT(0.492)T(0.492)PIS(0.016)EQK 269.88 1.8569e-55 1489088000.0 706140.1 679489.4 836235.4 783588.0 769465.8 880807.0 785053.0 845304.0 770404.0 757712.0 True False 930677.9631734828 899121.0604105657 825146.3722094963 602943.8929139185 662638.7556165167 825729.999049406 854921.1961508222 714681.6899535157 811125.9826290628 731184.733509582 1.2728356057249197 1.229677014856305 1.1285060182382527 0.8246122563580809 0.9062535433910738 1.1293042116539007 1.1692273607072223 0.9774297208355895 1.1093311244831032 1.0 19.47987642295103 -5.43610612129451 3.962953259162741 1.019542281614843 1.2473137549750972 0.46937440530035246 0.09914466748278647 0.21927221960912413 6.251399927498069 0.029236267365782356 0.06399954325438403 3.6634804535210628e-06 5.43610612129451 0.22777147336025427 DEILPT(ph)TPISEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DEILPTTPISEQK 13 0 P23396;P23396-2;E9PL09;E9PPU1;H0YEU2;E9PSF4 P23396 RPS3 40S ribosomal protein S3 1 DEILPT(0.931)T(0.069)PISEQK;DEILPT(0.92)T(0.08)PISEQK;DEILPT(0.666)T(0.332)PIS(0.002)EQK;DEILPT(0.689)T(0.309)PIS(0.002)EQK 219.84 2.0575e-14 1479256000.0 1348084.0 1480592.0 1331784.0 1619039.0 1606885.0 1392514.0 1560533.0 1218528.0 1344990.0 1094117.0 True False 1576287.9953273283 1627575.388868355 1363538.7813789425 1528329.493825261 1292027.4193704892 1319488.1144592045 1412708.0169594707 1186542.9311371353 1364657.9342789063 1292471.751074591 1.219591835579204 1.2592734715595533 1.054985364473355 1.18248580098913 0.9996562155391541 1.0209028656619779 1.0930281577024121 0.9180416749152281 1.055851265719578 1.0 20.3017013179263 -5.381561785545641 0.6164867120530425 1.0017703199759347 1.3168681510537827 0.6278850766840927 0.06282932353850654 1.1861328648442433 0.5594621156851243 0.033177919677618524 0.24041723128286202 4.153729533916874e-06 5.381561785545641 0.31509783107784806 DEILPT(ph)TPISEQK ddPTM_PC-9_Lapatinib_30min_R1 5 DEILPTTPISEQK 13 0 P23396;P23396-2;E9PL09;E9PPU1;H0YEU2;E9PSF4 P23396 RPS3 40S ribosomal protein S3 1 DEILPT(0.489)T(0.489)PIS(0.023)EQK;DEILPT(0.932)T(0.068)PISEQK;DEILPT(0.491)T(0.491)PIS(0.018)EQK;DEILPT(0.632)T(0.281)PIS(0.086)EQK;DEILPT(0.892)T(0.103)PIS(0.005)EQK 261.45 3.3108999999999997e-44 1853791200.0 571418.0 787730.0 614520.0 571771.0 608036.0 625280.0 558766.0 544755.0 585479.0 497275.0 True False 563269.474534774 785906.0595829868 563996.5377157982 613820.9467121422 572272.5179247705 598538.2319988712 587696.1694169649 570066.3060259019 519536.1896528071 583228.3211727128 0.9657786737828384 1.3475101106248482 0.9670252922247591 1.0524539437281029 0.9812152413553696 1.0262502870151682 1.0076605474769613 0.9774324828390609 0.8907938294357204 1.0 19.15370125209784 -5.362547562458103 23.690749422391892 0.9911953606528647 1.1569643822578848 0.3378946641190067 0.09441646592002478 22.951239046203785 5369.569704218146 0.022753815096313773 0.04736584667886945 4.339627349158998e-06 5.362547562458103 0.16576902160502005 DEILPTT(ph)PISEQK ddPTM_PC-9_AZD4547_30min_R2 4 DEILPTTPISEQK 13 0 P23396;P23396-2;E9PL09;E9PPU1;H0YEU2;E9PSF4 P23396 RPS3 40S ribosomal protein S3 1 DEILPT(0.021)T(0.658)PIS(0.321)EQK;DEILPT(0.286)T(0.712)PIS(0.002)EQK;DEILPT(0.136)T(0.863)PIS(0.001)EQK;DEILPT(0.447)T(0.553)PISEQK 219.84 2.0575e-14 1792028300.0 361826.0 478817.0 426258.0 509997.0 412267.0 465348.0 424277.0 495021.0 431384.0 456261.0 True False 476879.1415516685 633585.2314732288 420605.540407971 392425.0710251038 355030.8432964206 436249.7159964034 462036.8310665422 418526.8789009392 454186.0775521092 440287.44126503915 1.0831086623354362 1.4390263543579715 0.9552976101237004 0.8912929015135734 0.8063615039219418 0.9908293426289096 1.0493981607538303 0.9505764636357166 1.0315671876698012 1.0 18.748086167943846 -5.285219633903024 24.39849292753528 0.954086674453362 1.2610674780230429 0.5744967134783259 0.10376119261320847 332.1511671073454 340786.0493798735 0.026785036296601335 0.055811119813710654 5.185377347222315e-06 5.285219633903024 0.3069808035696808 DEILPTT(ph)PISEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 13 DEILPTTPISEQK 13 0 P23396;P23396-2;E9PL09;E9PPU1;H0YEU2;E9PSF4 P23396 RPS3 40S ribosomal protein S3 1 DEILPT(0.023)T(0.976)PIS(0.001)EQK;DEILPT(0.216)T(0.777)PIS(0.006)EQK;DEILPT(0.024)T(0.976)PISEQK;DEILPT(0.259)T(0.727)PIS(0.014)EQK;DEILPT(0.035)T(0.931)PIS(0.035)EQK;DEILPT(0.292)T(0.705)PIS(0.004)EQK;DEILPT(0.051)T(0.912)PIS(0.037)EQK;DEILPT(0.078)T(0.922)PISEQK;DEILPT(0.197)T(0.723)PIS(0.08)EQK;DEILPT(0.024)T(0.931)PIS(0.044)EQK;DEILPT(0.225)T(0.774)PIS(0.001)EQK;DEILPT(0.218)T(0.773)PIS(0.009)EQK;DEILPT(0.228)T(0.761)PIS(0.011)EQK 222.56 1.9126999999999997e-15 1624641800.0 886648.0 1071802.0 922942.0 1088628.0 1070162.0 918373.0 1083940.0 883403.0 854254.0 746740.0 True False 1036739.994303756 1178203.4192673478 944948.4375570277 1027635.7025395954 860471.4383221971 870211.9031767314 981261.3561539894 860214.6072928491 866745.8486602078 882118.0508094117 1.175284865050054 1.3356527714020303 1.0712267328505116 1.1649639201880746 0.9754606399139524 0.9865027729318594 1.1123923325836107 0.9751694872398717 0.9825735318134589 1.0 19.750612214029942 -5.720106110845578 1.2696908882679727 1.0093478267908231 1.2539456954725499 0.624491959952785 0.06967770903680116 0.30770658560075337 0.9700466412674575 0.02320291403006292 0.06279888588075949 1.9049952150430774e-06 5.720106110845578 0.24459786868172673 DEILPTT(ph)PISEQK ddPTM_PC-9_Lapatinib_30min_R1 5 DEILPTTPISEQK 13 0 P23396;P23396-2;E9PL09;E9PPU1;H0YEU2;E9PSF4 P23396 RPS3 40S ribosomal protein S3 1 DEILPT(0.039)T(0.957)PIS(0.004)EQK;DEILPT(0.02)T(0.979)PIS(0.001)EQK;DEILPT(0.002)T(0.998)PISEQK;DEILPT(0.209)T(0.789)PIS(0.002)EQK;DEILPT(0.19)T(0.806)PIS(0.004)EQK 269.88 1.8569e-55 1512227000.0 660271.0 759248.0 701333.0 614876.0 657845.0 671191.0 657169.0 615896.0 650537.0 555391.0 True False 650855.4144611285 757490.0079040566 643672.1079636712 660096.0322062063 619151.8504730315 642485.7255526396 691193.9952673875 644512.7765988893 577266.672601696 651389.5943380095 0.9991799379641245 1.1628831877086925 0.9881522725548274 1.0133659455783064 0.9505092741038635 0.9863309625103566 1.0611069032655183 0.9894428498721891 0.8862080045788224 1.0 19.313161147936583 -5.365948380267345 11.717759005765627 0.986549479654286 1.080984767540213 0.32308200510986584 0.05588811903774614 0.6502171899870149 69.28611830350644 0.014269701688236767 0.029715892115848477 4.305777854208254e-06 5.365948380267345 0.09443528788592714 DEILPTTPISEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DEILPTTPISEQK 13 0 P23396;P23396-2;E9PL09;E9PPU1;H0YEU2;E9PSF4 P23396 RPS3 40S ribosomal protein S3 0 119.27 0.0010618000000000001 1828600.0 15502.0 19137.0 17023.0 19403.0 23168.0 16040.0 18037.0 15415.0 15750.0 15825.0 False True 18126.182421543628 21036.794887973014 17428.892880087013 18315.912815374737 18628.396712879578 15198.834163193798 16328.404783428488 15010.37258354258 15980.313953927394 18693.947229368914 0.9696284149698836 1.1253265364376013 0.9323281309313609 0.9797777104345159 0.9964934898079548 0.8130350415944173 0.8734594456207693 0.8029536191244139 0.8548389357182791 1.0 14.190283606041863 -6.748825293975763 24.58861126360574 0.8568296453404791 1.002672008732766 0.4748533540161066 0.06873533083371218 146.78210750975174 286121.40667731676 0.0219657442292591 0.021818563743381907 1.7830959189714663e-07 6.748825293975763 0.14584236339228696 DEILPTTPISEQK ddPTM_PC-9_Lapatinib_30min_R1 3 DEILPTTPISEQK 13 0 P23396;P23396-2;E9PL09;E9PPU1;H0YEU2;E9PSF4 P23396 RPS3 40S ribosomal protein S3 0 ;; 173.04 0.00029296 21781900.0 146363.0 145737.0 158490.0 146241.0 153891.0 128099.0 149528.0 133807.0 125994.0 149432.0 False True 144275.83678031305 145399.55493055432 145459.56398909228 156996.05098567452 144839.43394134683 122620.50438335373 157269.82819387678 140024.16170646908 111803.22894436134 175261.12209437607 0.8232050271972023 0.8296167067346423 0.8299591047395212 0.8957836690166457 0.826420784087828 0.6996446383432603 0.8973457793405477 0.7989459386838098 0.6379237312206446 1.0 17.419146475199135 -6.531724296373888 24.989438772855 0.7957743083530044 0.8448421245668403 0.028051002865599473 0.09471493905632808 643.2866659619054 1817326.3004938008 0.029962393637855897 0.0300036228091026 2.939515155279805e-07 6.531724296373888 0.049067816213835824 DELADEIANS(ph)SGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DELADEIANSSGK 13 0 P35579;P35579-2 P35579 MYH9 Myosin-9 1 DELADEIANS(0.5)S(0.5)GK 64.313 0.042344 1716200.0 12904.0 23894.0 12735.0 14303.0 16741.0 7939.9 15710.0 8254.5 8050.2 8702.7 True False 15088.392334382597 26266.038410055236 13038.650697756442 13501.649280951653 13460.721226274043 7523.51766660489 14221.83506944955 8037.828121365695 8167.918945517859 10280.430619464705 1.4676809652131322 2.554955077496831 1.268298107383692 1.3133349935155416 1.3093538320065947 0.7318290395696123 1.3833890423346946 0.7818571438191583 0.7945113631770375 1.0 13.327613075944544 -5.435004402654285 5.6845955368253245 1.0640363333310228 2.0084366234347737 0.571231719435698 0.3295216991092633 0.14877319133572278 7.5050653011379085 0.0844247937512402 0.1781064921336891 3.6727857719773125e-06 5.435004402654285 0.9444002901037509 DELADEIANS(ph)SGKGALALEEK ddPTM_PC-9_AZD4547_30min_R2 1 DELADEIANSSGKGALALEEK 21 1 P35579;P35579-2 P35579 MYH9 Myosin-9 1 DELADEIANS(0.933)S(0.067)GKGALALEEK 62.871 0.0030636 6935500.0 14988.0 15410.0 14833.0 13283.0 13717.0 21456.0 18807.0 16545.0 15945.0 18275.0 True False 19753.87223023331 20390.981141025626 14636.304728289968 10220.80957030425 11812.631322654988 20114.35292817164 20480.78656601338 13988.350416277342 16787.820147637336 17635.197812477083 1.1201389652832385 1.1562660854645361 0.829948429494487 0.5795687510277272 0.6698326521915978 1.1405799437044324 1.1613584822690797 0.7932063232304909 0.9519496365251873 1.0 14.106170137988927 -6.778988256318327 24.99603611345792 1.005990430235572 0.8685025724420883 0.11669819113745317 0.1900143930850029 667.6433421992859 950962.8120760338 0.0765284611405366 0.06764038244897644 1.6634576310309644e-07 6.778988256318327 -0.13748785779348371 DELADEIANS(ph)SGKGALALEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DELADEIANSSGKGALALEEK 21 1 P35579;P35579-2 P35579 MYH9 Myosin-9 1 DELADEIANS(0.5)S(0.5)GKGALALEEK 48.968 0.024332 5009800.0 11553.0 14104.0 14519.0 13011.0 13319.0 12133.0 12466.0 9256.3 10489.0 11821.0 True False 13508.694717848888 15504.151909911243 14865.188023614131 12282.035852231134 10709.2375612415 11496.724121074212 11285.13023397569 9013.331932860536 10642.38178176155 13964.053725015483 0.9673906291014295 1.1102901933223586 1.0645324285013555 0.8795465911326917 0.7669146633299441 0.8233084996284963 0.8081557444711978 0.645466718357999 0.7621269576395697 1.0 13.769430192158906 -5.911494806554675 3.1666424289667647 0.7859086134768544 1.0548721899376259 0.5988865063513209 0.08936760243744454 0.15333425245245183 3.08176216864013 0.025906023972569164 0.04053712390184761 1.2260415640241364e-06 5.911494806554675 0.2689635764607715 DELADEIANSS(ph)GK ddPTM_PC-9_AZD4547_30min_R2 2 DELADEIANSSGK 13 0 P35579;P35579-2 P35579 MYH9 Myosin-9 1 DELADEIANS(0.018)S(0.982)GK;DELADEIANS(0.078)S(0.922)GK 229.9 7.1066e-20 11693000.0 79036.0 121106.0 83287.0 50365.0 65260.0 117796.0 120191.0 125116.0 121470.0 78113.0 True False 104167.80394907408 160251.14614309222 82182.55996124102 38754.127381493156 56199.77546959719 110430.19749845758 130887.76615918073 105782.1970796587 127890.65621408013 75378.28764574674 1.3819338061727886 2.1259589617665515 1.0902683322745688 0.5141285188597658 0.7455698082943689 1.4650133473108773 1.7364120391578854 1.403351023000156 1.6966511207461268 1.0 16.201861401494554 -6.966912126387366 24.977742428317665 1.508144740314306 1.1757257372504617 0.09324500684643844 0.4395846147051115 472.7953901370126 356907.76506137755 0.1723269178125603 0.15197717421880375 1.0791650545890366e-07 6.966912126387366 -0.3324190030638443 DELADEIANSS(ph)GK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DELADEIANSSGK 13 0 P35579;P35579-2 P35579 MYH9 Myosin-9 1 DELADEIANS(0.246)S(0.754)GK;DELADEIANS(0.078)S(0.922)GK;DELADEIANS(0.062)S(0.938)GK 211.77 1.2952e-10 11139500.0 82018.0 209947.0 111890.0 73347.0 84110.0 51945.0 92738.0 39405.0 60316.0 62708.0 True False 95902.02747065965 230789.15066861422 114557.88194518775 69237.60538418249 67629.24928868712 49220.91275605374 83953.18527502305 38370.66050304866 61198.00739333872 74076.46400374502 1.2946356006654316 3.115553013666344 1.5464815105023932 0.9346775162038257 0.9129654094351487 0.6644608840071703 1.1333314353500823 0.517987204425805 0.8261464449794038 1.0 16.17672761359556 -5.584075284075088 3.6558337189651215 0.8433827421461302 2.237153995750601 0.5988744484643064 0.44275278585142996 0.12898854501412416 3.4862905421368464 0.11368376941995638 0.2171749262793363 2.605701817676455e-06 5.584075284075088 1.3937712536044706 DELADEIANSS(ph)GK ddPTM_PC-9_Lapatinib_30min_R1 2 DELADEIANSSGK 13 0 P35579;P35579-2 P35579 MYH9 Myosin-9 1 DELADEIANS(0.02)S(0.98)GK;DELADEIANS(0.047)S(0.953)GK 286.88 7.7261e-83 12805200.0 94923.0 174655.0 97468.0 101769.0 141642.0 122331.0 155070.0 168901.0 101671.0 109945.0 True False 93569.38061325374 174250.59707827136 89454.55727736023 109253.4317514317 133310.89603888622 117099.18829748897 163098.76583666255 176748.7570634153 90219.74133690618 128948.84675749604 0.7256317754374517 1.3513156686540264 0.6937212664304815 0.8472617979817689 1.0338277494609436 0.9081057430293131 1.2648330709260982 1.3706889321454174 0.699655278860891 1.0 16.97643934500728 -7.2313773554812 24.120357067618 1.1146851220711316 0.9366235416014811 0.0881825980122698 0.23816399432480093 1009.3842158521898 809883.2165134684 0.08873873261024484 0.06872659167047863 5.869791087873864e-08 7.2313773554812 -0.17806158046965048 DELADEIANSS(ph)GKGALALEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DELADEIANSSGKGALALEEK 21 1 P35579;P35579-2 P35579 MYH9 Myosin-9 1 DELADEIANS(0.305)S(0.695)GKGALALEEK 58.711999999999996 0.005901 5071300.0 11954.0 12688.0 8221.5 12733.0 12279.0 8618.8 13074.0 10070.0 9461.3 7467.2 True False 13977.57609773787 13947.580787929237 8417.531740212378 12019.611290942983 9873.018095539037 8166.814955469744 11835.536072436882 9805.673170046952 9599.653613478937 8820.944249677319 1.5845895521048314 1.5811890873745695 0.9542665163675988 1.3626218407833919 1.119269980183834 0.925843619946753 1.3417538686824646 1.1116353184530845 1.088279592497153 1.0 13.106717383915578 -5.2471453339181995 24.621149424391206 1.127576319272818 1.5828894497753994 0.6492048810337797 0.13784036285993215 389.825236604544 671461.0494973959 0.03398408392242393 0.08895107317992726 5.660498323218278e-06 5.2471453339181995 0.45531313050258126 DELADEIANSS(ph)GKGALALEEK ddPTM_PC-9_Lapatinib_30min_R1 1 DELADEIANSSGKGALALEEK 21 1 P35579;P35579-2 P35579 MYH9 Myosin-9 1 DELADEIANS(0.121)S(0.879)GKGALALEEK 47.105 0.029827999999999997 6402500.0 17056.0 19477.0 16137.0 17931.0 17040.0 22201.0 18439.0 18678.0 15694.0 16593.0 True False 16812.77831231268 19431.90220316331 14810.278150621372 19249.705556062494 16037.740701928979 21251.5149830587 19393.681197280097 19545.848067391365 13926.376454853475 19461.077941217292 0.8639181428231327 0.998500815928999 0.7610204427193712 0.9891387113399754 0.8240931335032625 1.0920009183072732 0.9965368442518565 1.00435588030787 0.7156014942706909 1.0 14.248304002175075 -6.720136518559254 24.999997260002413 0.9641496877544012 0.8921486309777342 0.0983460230571842 0.11198836763364164 386.85585475184075 234156.8327608819 0.036127703403663204 0.03612734215634229 1.904861838904049e-07 6.720136518559254 -0.07200105677666702 DELADEIANSSGK ddPTM_PC-9_Lapatinib_30min_R1 2 DELADEIANSSGK 13 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 191.29 6.2542e-36 3736200.0 65886.0 63492.0 54607.0 56154.0 53391.0 49787.0 54720.0 54993.0 52680.0 57633.0 False True 64946.453557987385 63344.98817493689 50117.42324911574 60283.75248425263 50250.64635074468 47657.72606916554 57553.13385298372 57548.17554181671 46746.62365500703 67594.78725885475 0.9608204447670565 0.9371283015117242 0.7414391742545278 0.8918402576428793 0.7434100821755597 0.7050503152951709 0.851443375841743 0.8513700223870154 0.6915714295540347 1.0 16.044624373308842 -5.173819572743209 6.401183540082354 0.8027212718837986 0.9529843347499394 0.2758049787856274 0.08997983702819545 0.28097842241046433 16.91052451561787 0.021704205209325908 0.05898908152757899 6.701629702009212e-06 5.173819572743209 0.15026306286614077 DELHIVEAEAMNY(ph)EGSPIKVTLATLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DELHIVEAEAMNYEGSPIKVTLATLK 26 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 DELHIVEAEAMNY(0.525)EGS(0.474)PIKVTLATLK 63.122 0.00065407 6187300.0 69981.0 75120.0 70787.0 74026.0 82912.0 68483.0 84103.0 63950.0 65026.0 58064.0 True False 81827.40111224631 82577.41714921544 72474.83054119241 69878.5632155302 66665.98878877204 64891.63092256859 76136.15498700931 62271.3802606259 65976.88223289406 68590.54356562885 1.192983709685172 1.203918395401017 1.0566300655111005 1.0187783852254932 0.9719413977961066 0.9460725567873498 1.1100095002769685 0.9078712169855215 0.9618947278026163 1.0 16.06572206831813 -5.423861834819296 1.9088733044449138 0.9847212439385163 1.2104361383431013 0.7309743758747598 0.050401105343995244 0.1856172254315201 1.2746085329283432 0.01473212134623473 0.04579671304093161 3.768236614979438e-06 5.423861834819296 0.22571489440458492 DELHIVEAEAMNY(ph)EGSPIKVTLATLK ddPTM_PC-9_Lapatinib_30min_R1 1 DELHIVEAEAMNYEGSPIKVTLATLK 26 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 DELHIVEAEAMNY(0.554)EGS(0.444)PIKVT(0.002)LATLK 65.21300000000001 0.00031638 16570000.0 40056.0 36160.0 39209.0 38853.0 33658.0 42994.0 38623.0 40869.0 34405.0 37984.0 True False 39484.79409462924 36076.27374166377 35985.38737111691 41710.37922980852 31678.30261417404 41155.24684390911 40622.709956209575 42767.92293961975 30529.94659928851 44549.483789501406 0.8863131676496391 0.8098022844019026 0.8077621626582635 0.9362707641438046 0.7110812498716179 0.9238097356721294 0.9118559072009444 0.9600093940863687 0.6853041607293155 1.0 15.443121094379899 DELHIVEAEAMNYEGS(ph)PIK ddPTM_PC-9_AZD4547_30min_R2 10 DELHIVEAEAMNYEGSPIK 19 0 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 DELHIVEAEAMNY(0.45)EGS(0.55)PIK;DELHIVEAEAMNY(0.122)EGS(0.878)PIK;DELHIVEAEAMNY(0.426)EGS(0.574)PIK;DELHIVEAEAMNY(0.268)EGS(0.732)PIK;DELHIVEAEAMNYEGS(1)PIK;DELHIVEAEAMNY(0.224)EGS(0.776)PIK;DELHIVEAEAMNY(0.023)EGS(0.977)PIK;DELHIVEAEAMNY(0.006)EGS(0.994)PIK;DELHIVEAEAMNYEGS(1)PIK;DELHIVEAEAMNYEGS(1)PIK 229.23 1.2497e-35 332274800.0 731022.9 1196849.0 886711.0 564733.0 683448.0 1088329.0 1136586.0 1216663.0 1138819.0 856581.7 True False 963472.975979093 1583707.033592174 874952.6327733243 434542.53188787436 588563.0423712123 1020275.6155837126 1237739.9521411662 1028655.6894843916 1199014.6473949326 826593.035406178 1.1655953228612117 1.9159452907971324 1.058504723964173 0.5257031129887821 0.712034843218827 1.2343143141562538 1.497399444616607 1.2444524033267743 1.4505501450369118 1.0 19.656817682539177 -6.990654021544154 24.87811593288854 1.325240927705065 1.0789926218213146 0.07781656321333608 0.36150328427123196 553.7409270363656 1473998.4014033703 0.1428407523550432 0.12580456684743824 1.02175313392624e-07 6.990654021544154 -0.24624830588375035 DELHIVEAEAMNYEGS(ph)PIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 DELHIVEAEAMNYEGSPIK 19 0 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 DELHIVEAEAMNY(0.05)EGS(0.95)PIK;DELHIVEAEAMNY(0.08)EGS(0.92)PIK;DELHIVEAEAMNY(0.001)EGS(0.999)PIK;DELHIVEAEAMNY(0.006)EGS(0.994)PIK;DELHIVEAEAMNYEGS(1)PIK;DELHIVEAEAMNY(0.379)EGS(0.621)PIK;DELHIVEAEAMNY(0.348)EGS(0.652)PIK;DELHIVEAEAMNY(0.008)EGS(0.992)PIK 144.95 2.0748000000000002e-05 244260000.0 906902.0 2072993.0 1162942.0 941268.0 1039620.0 633213.4 1047638.0 534627.5 614167.6 696257.0 True False 1060422.5964690235 2278786.0451065395 1190670.947762098 888531.8055920297 835913.9239746146 600006.5745955177 948398.1443977068 520594.0946096587 623148.6392590532 822482.8825326216 1.2892944266556996 2.77061820191274 1.4476543804726212 1.0803043132715755 1.0163298735174107 0.7295064582352813 1.153091650342147 0.6329543211970867 0.7576432926363518 1.0 19.64962612830928 -5.607159813339893 3.057958346898864 0.8952236643073763 2.048650718889488 0.5906137152231006 0.3710750804590666 0.14938715500624633 2.7913537154152026 0.09786221750513628 0.1923190293564538 2.470814757867981e-06 5.607159813339893 1.1534270545821115 DELHIVEAEAMNYEGS(ph)PIK ddPTM_PC-9_Lapatinib_30min_R1 11 DELHIVEAEAMNYEGSPIK 19 0 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 DELHIVEAEAMNY(0.023)EGS(0.977)PIK;DELHIVEAEAMNY(0.006)EGS(0.994)PIK;DELHIVEAEAMNYEGS(1)PIK;DELHIVEAEAMNYEGS(1)PIK;DELHIVEAEAMNY(0.004)EGS(0.996)PIK;DELHIVEAEAMNYEGS(1)PIK;DELHIVEAEAMNY(0.051)EGS(0.949)PIK;DELHIVEAEAMNY(0.003)EGS(0.997)PIK;DELHIVEAEAMNYEGS(1)PIK;DELHIVEAEAMNY(0.047)EGS(0.953)PIK;DELHIVEAEAMNYEGS(1)PIK 190.85 1.4872e-11 221593300.0 341810.0 818979.0 597460.0 645845.0 874634.0 741588.0 947633.0 993230.0 681994.0 783666.0 True False 336935.7267197236 817082.7044434217 548339.1450622946 693342.5957757627 823189.7477166055 709872.0099660623 996696.7999361209 1039379.0917643812 605180.6540048007 919121.6239306933 0.3665844845198968 0.8889821359540053 0.5965904084785653 0.7543534802397865 0.8956265702858477 0.7723374050653284 1.0844014263027253 1.130839558881661 0.6584337026221838 1.0 19.809896255028114 -4.345049926419499 0.39469879960408594 0.9778239352028735 2.5579271248056127e-15 0.43937737852115444 0.16697582371203615 8.036787281460402 0.7607353281692831 0.1343581927999276 3.9784402782627204 4.5180400207839177e-05 4.345049926419499 -0.9778239352028709 DELHIVEAEAMNYEGS(ph)PIKVTLATLK ddPTM_PC-9_AZD4547_30min_R2 4 DELHIVEAEAMNYEGSPIKVTLATLK 26 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 DELHIVEAEAMNY(0.018)EGS(0.981)PIKVT(0.001)LATLK;DELHIVEAEAMNY(0.454)EGS(0.544)PIKVT(0.002)LATLK;DELHIVEAEAMNY(0.449)EGS(0.546)PIKVT(0.003)LAT(0.002)LK;DELHIVEAEAMNY(0.444)EGS(0.556)PIKVT(0.001)LATLK 104.23 5.0954e-10 73304800.0 112382.0 122538.8 118694.6 114563.2 125177.6 144459.6 136708.4 156258.2 145507.5 127308.1 True False 148117.1383091859 162147.0707231611 117120.63205032598 88152.42422379582 107798.85096265783 135426.51837539638 148875.1827607375 132112.08564622246 153198.7293905514 122851.08216856992 1.205664090984133 1.3198668490414374 0.9533545002853054 0.7175551298997725 0.8774757947572802 1.1023632513840709 1.211834524635759 1.0753839796457394 1.2470279193824276 1.0 16.90655104058095 -9.524444460296124 15.187284760037763 0.9999997778817488 1.0702768279322687 0.01575231537845967 0.1755607320519102 0.0 0.0 0.19027217711384087 0.04614778140332926 2.989203896540976e-10 9.524444460296124 0.07027705005051998 DELHIVEAEAMNYEGS(ph)PIKVTLATLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DELHIVEAEAMNYEGSPIKVTLATLK 26 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 DELHIVEAEAMNY(0.214)EGS(0.76)PIKVT(0.022)LAT(0.004)LK;DELHIVEAEAMNY(0.038)EGS(0.959)PIKVT(0.003)LATLK;DELHIVEAEAMNY(0.215)EGS(0.769)PIKVT(0.013)LAT(0.002)LK 103.35 6.158799999999999e-10 31899800.0 147388.0 147780.0 143006.4 155260.0 175439.0 140529.0 159610.0 121321.2 130770.6 115557.3 True False 172337.87735430742 162450.62175600437 146416.2149307923 146561.28555971137 141062.9873493988 133159.4118528343 144490.58532366916 118136.64705043669 132682.87263133086 136506.92373891652 1.2624845145871229 1.190054081554924 1.0725918577641405 1.073654592348919 1.0333760624420505 0.9754773472700574 1.058485396682312 0.8654260444428821 0.9719863945150536 1.0 17.05861460206893 -3.9434830709698194 0.4197139193645854 0.9528161403803254 1.8095749303117503 0.8116074846662206 0.046422041088594254 4.236686511444027 0.34076333065343856 0.0335566782588957 2.0941993195987036 0.00011389821791422752 3.9434830709698194 0.856758789931425 DELHIVEAEAMNYEGS(ph)PIKVTLATLK ddPTM_PC-9_Lapatinib_30min_R1 4 DELHIVEAEAMNYEGSPIKVTLATLK 26 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 DELHIVEAEAMNY(0.192)EGS(0.795)PIKVT(0.013)LAT(0.001)LK;DELHIVEAEAMNY(0.449)EGS(0.548)PIKVT(0.002)LATLK;DELHIVEAEAMNY(0.444)EGS(0.55)PIKVT(0.006)LAT(0.001)LK;DELHIVEAEAMNY(0.012)EGS(0.755)PIKVT(0.227)LAT(0.007)LK 121.48 1.9373e-12 53044200.0 67267.4 89191.0 75681.5 66741.8 78601.0 76249.0 70208.7 73255.0 71835.7 67590.3 True False 66308.15454066948 88984.48371937878 69459.2592090382 71650.21461611817 73977.84371551173 72988.00801510045 73843.7629521925 76658.69473052533 63744.80700254353 79273.1932965863 0.8364511606412716 1.1225040902094034 0.8762011005305281 0.9038391369961832 0.9332012580688787 0.9207148719495762 0.9315098822362237 0.9670191339930095 0.8041155446337815 1.0 16.274545472007766 DELHIVEAEAMNYEGSPIKVTLATLK ddPTM_PC-9_AZD4547_30min_R2 3 DELHIVEAEAMNYEGSPIKVTLATLK 26 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 0 ;; 157.28 5.3468e-12 25860300.0 110210.3 109370.2 140484.0 111888.3 127670.2 148735.5 133205.4 137281.7 125741.8 123160.9 False True 145254.88288335243 144721.9782991695 138621.09036938514 86094.18109200288 109945.39647806586 139435.04567244957 145060.4225469475 116067.96768463321 132388.25484102758 118849.07437826063 1.2221793366353877 1.2176954600299474 1.1663623893964556 0.7243992563037652 0.925084162861403 1.1732110359452192 1.2205431410030512 0.9765996772951214 1.1139191073518657 1.0 16.858771141746665 -5.542451136298008 24.99820208802956 1.0225949517546178 1.2129604885579615 0.2959474296863466 0.1309088701386518 313.09643860706063 399890.64197835483 0.03890736974631484 0.06740082176831759 2.8678000217315255e-06 5.542451136298008 0.19036553680334367 DELHIVEAEAMNYEGSPIKVTLATLK ddPTM_PC-9_Lapatinib_30min_R1 3 DELHIVEAEAMNYEGSPIKVTLATLK 26 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 0 ;; 177.09 9.0379e-18 16267600.0 91096.9 95265.1 92038.4 94838.1 111465.5 91205.5 93238.8 84101.6 95251.5 86735.9 False True 89797.84150087467 95044.51951402014 84471.35803049833 101812.81024462746 104909.31843960458 87304.85337540487 98066.24884304788 88009.26736398552 84523.27302723813 101728.08474667775 0.8827241928764151 0.9342997044591869 0.830364183507908 1.0008328624112082 1.0312719314518572 0.858217802810409 0.964003687745144 0.8651422818304828 0.8308745145228786 1.0 16.634358503005316 -10.52171676818973 24.1883903648365 0.9999999829690263 0.9140389942242688 0.13670008932461997 0.0667750098565165 0.0 0.0 0.06619550112891096 0.016054767240893705 3.008037400825426e-11 10.52171676818973 -0.08596098874475744 DELT(ph)ESPK ddPTM_PC-9_AZD4547_30min_R2 1 DELTESPK 8 0 Q8NC51;Q8NC51-2 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 DELT(0.709)ES(0.291)PK 133.75 0.010013 36441000.0 362680.0 452740.0 221860.0 123630.0 167910.0 298090.0 345730.0 264370.0 313740.0 221240.0 True False 478004.69578736543 599079.3511867576 218917.99143925094 95129.01356445947 144598.5948375737 279450.38517704513 376499.3002322435 223517.69111823756 330323.6558870957 213494.45494021534 2.2389560231024297 2.8060651568422106 1.025403641047981 0.44558072288621436 0.6772943816178529 1.3089350974258296 1.7635085667104293 1.0469484614053748 1.5472235847043239 1.0 17.703839073865055 -7.799686180853574 24.987611726589847 1.2228149968103608 1.4254054762057689 0.029300195021004338 0.6753895271342027 1171.319894238026 765238.267878538 0.42066636322849443 0.2020877289597154 1.5860388426855698e-08 7.799686180853574 0.20259047939540809 DELT(ph)ESPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DELTESPK 8 0 Q8NC51;Q8NC51-2 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 DELT(0.605)ES(0.395)PK 102.53 0.010393000000000001 19365000.0 106660.0 171880.0 91409.0 75056.0 84933.0 64967.0 132610.0 66579.0 65013.0 87133.0 True False 124715.43136897459 188943.11048465248 93588.53723056293 70850.85565483516 68290.98834664203 61560.01615213286 120048.22078674096 64831.3717962816 65963.69213248773 102929.52315555142 1.2116584974410052 1.8356551618247927 0.9092487204971114 0.6883433779029791 0.6634732800951367 0.5980792902256118 1.1663147472792528 0.6298617715182233 0.6408627001292975 1.0 16.65129732256844 -5.40159572194464 5.4200886737796194 0.7619645987330091 1.5163372483573143 0.6415529559763613 0.2219101139820625 0.1234600522866597 4.9173171943392235 0.05643241268210024 0.12013300534312465 3.96647095134134e-06 5.40159572194464 0.7543726496243052 DELT(ph)ESPK ddPTM_PC-9_Lapatinib_30min_R1 1 DELTESPK 8 0 Q8NC51;Q8NC51-2 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 DELT(0.991)ES(0.009)PK 89.029 0.025751999999999997 47399000.0 82324.0 121150.0 64077.0 106370.0 109880.0 97757.0 158980.0 143200.0 81533.0 123040.0 True False 81150.04466362731 120869.48461843381 58808.83640437288 114192.80463991799 103417.0744323917 93576.16099269714 167211.20650488557 149853.59477730162 72349.89495944745 144307.30005950545 0.5623419233134076 0.8375839931077153 0.4075250273556703 0.7913168952147973 0.7166447878225664 0.648450639393231 1.1587162010233414 1.0384339164789942 0.5013599099256504 1.0 17.13878475758718 -7.221486215315777 24.822940707518637 0.9278304104104856 0.6656663212621658 0.30639437320601715 0.19446818485219433 602.157080420796 374121.1884401246 0.07301273551261804 0.05655462083262007 6.005010687542296e-08 7.221486215315777 -0.2621640891483198 DELTES(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 DELTESPK 8 0 Q8NC51;Q8NC51-2 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 DELT(0.004)ES(0.996)PK 113.69 0.0037099000000000004 38248000.0 235520.0 325860.0 126940.0 75875.0 103420.0 195690.0 222770.0 163960.0 207790.0 139550.0 True False 310410.46087967383 431187.8724603899 125256.69265887742 58383.19100706429 89061.91815914394 183453.4733647424 242596.09843732684 138623.74942597953 218773.35518830764 134664.3969757144 2.3050670247731015 3.20194410804922 0.9301396320919658 0.43354585412500096 0.6613620241080166 1.3623012279765876 1.8014865390224637 1.0294016275955937 1.6245819986685983 1.0 17.03900895110256 -7.776519945338175 24.72237473954621 1.2452440918205923 1.4875705408188784 0.030030391936882617 0.7795229907216912 1454.8294964427996 2384940.2559620566 0.48044967523830406 0.23228400045134334 1.6729388035172793e-08 7.776519945338175 0.24232644899828615 DELTES(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DELTESPK 8 0 Q8NC51;Q8NC51-2 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 DELT(0.231)ES(0.769)PK 113.69 0.0037099000000000004 21944000.0 183690.0 321880.0 143380.0 129490.0 179020.0 106520.0 217990.0 115570.0 116420.0 148640.0 True False 214785.08895712497 353834.11916918796 146798.72297167825 122235.09511224445 143942.3161058226 100933.90368225696 197340.4090890709 112536.40995653677 118122.4222549987 175587.25536640716 1.2232384890857917 2.0151469332487926 0.8360442941336809 0.6961501554151527 0.8197765595541122 0.5748361603559032 1.123887999030854 0.6409144543076383 0.6727277672203853 1.0 17.42182860810881 -5.328814778575456 8.217657681514813 0.7822347743692684 1.6173285325113835 0.6578987709270665 0.2374716970482508 0.1579515698552066 17.84853425150193 0.05761729906965305 0.12064616241829977 4.690133681124642e-06 5.328814778575456 0.8350937581421152 DELTES(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 DELTESPK 8 0 Q8NC51;Q8NC51-2 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 DELT(0.122)ES(0.878)PK 137.46 0.0032046999999999996 56404000.0 163010.0 305460.0 132320.0 228440.0 294870.0 233950.0 384200.0 308010.0 188230.0 278650.0 True False 160685.44750762687 304752.72613740654 121441.16036997101 245240.23965350105 277526.32633672527 223944.50386408632 404091.9960949619 322321.26904578746 167029.55525022745 326814.2812222141 0.49167204966288 0.9324951314786424 0.3715907392902402 0.750396337443872 0.8491866551817667 0.6852347548172704 1.2364575825259103 0.9862520935143233 0.5110840157461093 1.0 18.318111502590824 -6.41985741529481 1.5657737615824403 0.9115316879120462 0.631140476947816 0.22546980251650595 0.22599540980619817 0.6109026090978236 3.0132708589666226 0.08724372289170294 0.10428191850869842 3.8031423809273827e-07 6.41985741529481 -0.28039121096423014 DELTES(ph)PKYIQK ddPTM_PC-9_AZD4547_30min_R2 2 DELTESPKYIQK 12 1 Q8NC51;Q8NC51-2 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 DELT(0.012)ES(0.987)PKY(0.001)IQK;DELT(0.024)ES(0.974)PKY(0.002)IQK 86.944 0.0041741999999999994 32709000.0 257740.0 192092.0 223555.0 274500.0 277600.0 214121.0 214690.0 194808.0 213905.0 258290.0 True False 339695.95867496147 254181.9824362035 220590.5146317579 211218.26598272365 239060.03172479625 200731.98002111446 233796.9940903608 164704.8998424992 225211.58160428755 249247.34571735718 1.362886965545349 1.0197981515295338 0.8850265345730273 0.847424334148144 0.9591276931626257 0.8053525282020118 0.938011971270832 0.6608090423930617 0.9035666195606118 1.0 17.92721861560674 -4.628348881653308 1.5873309888394902 0.8612607608060642 1.7072045600738681 0.7306319361223559 0.08961488148459945 0.7519263620290826 1.3604117740043844 0.024016624103716015 1.1083825693832623 2.3531581625737853e-05 4.628348881653308 0.8459437992678039 DELTES(ph)PKYIQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DELTESPKYIQK 12 1 Q8NC51;Q8NC51-2 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 DELT(0.053)ES(0.941)PKY(0.006)IQK 61.167 0.026868 10554000.0 65700.0 27990.0 43099.0 67225.0 72745.0 73850.0 87805.0 95457.0 71721.0 67986.0 True False 76821.71236585059 30768.66222053429 44126.643613867695 63458.601196390555 58491.139454351935 69977.17599450512 79487.47474685022 92951.3548950518 72769.78394219866 80311.32362312 0.9565489510091348 0.38311735920234063 0.549444855633839 0.7901575809431948 0.7283050112439378 0.8713239034994575 0.9897418092604738 1.1573879087244054 0.9060961849376084 1.0 16.29331579672128 -6.784646524398315 1.2330540731492525 1.0344447836364128 0.6290013481520774 0.5198405742875265 0.1510781227676714 0.337604894974253 1.0800952721077082 0.07546303416212774 0.06656916929695729 1.641925605316635e-07 6.784646524398315 -0.40544343548433537 DELTES(ph)PKYIQK ddPTM_PC-9_Lapatinib_30min_R1 1 DELTESPKYIQK 12 1 Q8NC51;Q8NC51-2 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 DELT(0.003)ES(0.997)PKYIQK 88.706 0.0037223 13814000.0 124700.0 95238.0 103650.0 118570.0 102410.0 105600.0 87195.0 90670.0 109600.0 93691.0 True False 122921.75513282066 95017.48226240544 95128.29710057034 127290.03333792475 96386.44514580678 101083.73416562314 91709.53045158827 94882.85920710856 97255.6938608348 109885.36451458959 1.1186362776864631 0.8646964287022033 0.8657048872776871 1.1583893260055058 0.8771545289182661 0.9199017049463595 0.8345927672598467 0.8634713059946293 0.8850650338236997 1.0 16.745639722887113 DENSVPAAYYLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DENSVPAAYYLR 12 0 Q9ULI1 Q9ULI1 NWD2 NACHT and WD repeat domain-containing protein 2 0 84.81700000000001 0.046088 749520000.0 111330.0 114390.0 100030.0 139130.0 144250.0 115420.0 86330.0 139780.0 88546.0 91971.0 False True 130175.97013227035 125745.88322282641 102415.09456588731 131334.99716554623 115985.24800728913 109367.17201470253 78152.19742492544 136110.92310915215 89840.81773742569 108644.61425796467 1.1981815299484782 1.1574055840840547 0.9426614956054237 1.2088495878286774 1.067565555821248 1.0066506541688502 0.7193379806141302 1.2528087474816907 0.8269238042864101 1.0 16.72925713330106 -6.739785476452432 3.470206268544854 0.9591408466010444 1.1167997555282132 0.22650313039464354 0.14551111115285378 0.38283933678499754 9.667040659487004 0.05036980132770415 0.04761325225634856 1.8205999377575606e-07 6.739785476452432 0.15765890892716883 DENSVPAAYYLR ddPTM_PC-9_Lapatinib_30min_R1 1 DENSVPAAYYLR 12 0 Q9ULI1 Q9ULI1 NWD2 NACHT and WD repeat domain-containing protein 2 0 91.265 0.029941000000000002 1061200000.0 156250.0 145030.0 124940.0 134020.0 138960.0 140710.0 123630.0 102840.0 124470.0 107630.0 False True 154021.84634725942 144694.19194561636 114667.91548234687 143876.2778776138 130786.64600587136 134692.16131103074 130030.95647376415 107618.32183587797 110450.87787279284 126233.70209203957 1.2201325303361454 1.1462405803492706 0.9083779813313259 1.1397612166417384 1.0360675781378268 1.0670063467902093 1.0300811456749952 0.8525324065788014 0.8749713907008831 1.0 16.945737609399934 -7.61512136976483 4.371152649941489 0.8988554360875299 1.0790284430142492 0.4598836371582242 0.08516108214563332 0.1951593715478597 6.737322588402416 0.043025824706438266 0.02386890687907375 2.4259320391568087e-08 7.61512136976483 0.18017300692671923 DEPAES(ph)PSETPGPR ddPTM_PC-9_Lapatinib_30min_R1 1 DEPAESPSETPGPR 14 0 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 DEPAES(0.954)PS(0.045)ETPGPR 212.03 1.1393e-11 5007500.0 19078.0 28717.0 33295.0 28618.0 32602.0 33185.0 33174.0 41384.0 38594.0 29940.0 True False 18805.94422152329 28650.507550867205 30557.613622416713 30722.663186849426 30684.414457998148 31765.754908013318 34891.587398371375 43306.85171971965 34247.13730716291 35115.08910745771 0.5355516588317385 0.8159030285582399 0.8702131875247588 0.874913433733095 0.8738241946104424 0.9046183767555053 0.9936351661132802 1.2332832642740519 0.975282654199204 1.0 15.099803475683773 -4.100447467747427 0.36887222601719155 1.0668729756452853 3.253980153041143e-14 0.7078836351115378 0.08995903178523905 6.006376945541069 0.4416993830052566 0.08235640287111211 3.135142378751051 7.935102339556673e-05 4.100447467747427 -1.0668729756452526 DEPAES(ph)PSETPGPRPAGPAGDEPAESPSETPGPR ddPTM_PC-9_AZD4547_30min_R2 1 DEPAESPSETPGPRPAGPAGDEPAESPSETPGPR 34 1 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 DEPAES(0.333)PS(0.333)ET(0.333)PGPRPAGPAGDEPAESPSETPGPR 63.724 3.368e-05 4245700.0 2849.4 5398.9 4136.2 4983.1 4509.1 5030.8 6239.6 6082.3 3887.5 2824.7 True False 3755.449928798158 7143.988843756217 4081.351285454929 3834.323283127544 3883.0892977315457 4716.2232807161545 6794.912312293145 5142.42029234957 4092.9853135114527 2725.808112771765 1.3777381875129102 2.6208700496132065 1.497299559103875 1.4066739566742923 1.4245644363362715 1.7302110367264318 2.492806548067564 1.886567241565823 1.5015676614702933 1.0 11.412468289763225 -8.57577790497601 3.4417734377087146 1.0012893169257309 1.8135220021038174 0.26157600461237707 0.41640077909582285 0.38411070395039537 12.445500988238445 0.4147293858689342 0.1094828145369725 2.655963455037368e-09 8.57577790497601 0.8122326851780866 DEPAES(ph)PSETPGPRPAGPAGDEPAESPSETPGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DEPAESPSETPGPRPAGPAGDEPAESPSETPGPR 34 1 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 DEPAES(0.907)PS(0.072)ET(0.021)PGPRPAGPAGDEPAESPSETPGPR 54.934 0.00047164 4866600.0 3125.5 7275.5 5529.5 4105.5 6158.5 3665.9 4828.3 3582.4 3540.1 4571.2 True False 3654.585418561128 7997.763557895577 5661.344250745528 3875.482145210587 4951.78613416216 3473.6537505518786 4370.928470135154 3488.365795866552 3591.8672652887885 5399.9223744007095 0.676784806368021 1.4810886163494488 1.0484121545124678 0.7176921956476631 0.9170106143816033 0.6432784602644199 0.8094428340037473 0.6460029522653454 0.6651701665780739 1.0 12.398722952887807 -5.691487747853322 5.214229784997625 0.7588307006343193 1.1200534743615627 0.28572863186336805 0.21233099658768434 0.20959600909498652 10.503743401915907 0.054950527664687186 0.09584568493064057 2.0347555987727923e-06 5.691487747853322 0.3612227737272433 DEPAESPS(ph)ETPGPRPAGPAGDEPAESPSETPGPR ddPTM_PC-9_Lapatinib_30min_R1 1 DEPAESPSETPGPRPAGPAGDEPAESPSETPGPR 34 1 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 DEPAES(0.138)PS(0.431)ET(0.431)PGPRPAGPAGDEPAESPSETPGPR 80.245 1.1548e-08 6468100.0 2871.7 4915.7 3744.1 3040.8 7086.2 5214.7 5865.1 5680.8 4760.9 4828.2 True False 2830.749031394717 4904.317998669708 3436.2745506439514 3264.4305758114374 6669.4036480052255 4991.679437059427 6168.766179845294 5944.750706779999 4224.677307500439 5662.747936827896 0.4998896406786594 0.8660668024395523 0.6068210326467137 0.5764746395616674 1.177768059325139 0.8814941955293207 1.0893591324675584 1.0497996331636248 0.7460472114651422 1.0 12.467286597927144 -6.249808956166714 24.98095069122136 0.9927028854617233 0.6514745704737845 0.6030913780084115 0.1402704612100649 521.4129422576843 1119940.7253306746 0.04022802980344163 0.051486383674497566 5.625887505656891e-07 6.249808956166714 -0.3412283149879387 DEQLS(ph)PEEEEK ddPTM_PC-9_AZD4547_30min_R2 1 DEQLSPEEEEK 11 0 P15408;P15408-3;P15408-2;C9JCN8 P15408 FOSL2 Fos-related antigen 2 1 DEQLS(1)PEEEEK 122.1 0.00070294 4839100.0 17579.0 20343.0 17634.0 12817.0 16203.0 19680.0 22791.0 19842.0 16288.0 16596.0 True False 23168.756334085363 26918.476920952908 17400.16163814908 9862.23867067602 13953.493134138575 18449.406488926994 24819.35484798273 16775.87482380024 17148.950427388958 16014.97909142926 1.44669288681648 1.6808312247724928 1.0864929350710877 0.6158133965940672 0.8712776366724118 1.15200940217278 1.5497588043224675 1.0475115033261697 1.0708069195398804 1.0 13.967134294133416 -5.285541035698458 11.188723368816097 1.0505231102505406 1.5637276342535593 0.4526149878190351 0.2263429204659641 0.7643910446795791 354.39854708965953 0.06617228674141516 0.1401083725373417 5.181541302494712e-06 5.285541035698458 0.5132045240030187 DEQLS(ph)PEEEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DEQLSPEEEEK 11 0 P15408;P15408-3;P15408-2;C9JCN8 P15408 FOSL2 Fos-related antigen 2 1 DEQLS(1)PEEEEK 106.29 0.0048107 0.0 18728.0 24164.0 17430.0 18885.0 20198.0 14431.0 20835.0 16979.0 14466.0 15084.0 True False 21898.280505139275 26562.842225687415 17845.5973036431 17826.934675996075 16240.34689255619 13674.21295567641 18861.35796766272 16533.319240737557 14677.537883016754 17818.609795121698 1.2289556119655582 1.4907359514073693 1.0015145686914806 1.0004672014803677 0.9114261482398252 0.7674118863874597 1.0585201755092308 0.9278680789824567 0.823719585971017 1.0 14.121097161980462 -5.380032663406968 4.7546052012934386 0.9274987356561117 1.356946854756497 0.742827230319117 0.10020683899094403 0.09988928291856258 3.4189278518020547 0.026166265489781893 0.05683769414384505 4.168380317887932e-06 5.380032663406968 0.42944811910038516 DEQLS(ph)PEEEEK ddPTM_PC-9_Lapatinib_30min_R1 1 DEQLSPEEEEK 11 0 P15408;P15408-3;P15408-2;C9JCN8 P15408 FOSL2 Fos-related antigen 2 1 DEQLS(1)PEEEEK 119.32 0.00097708 5421200.0 22536.0 26627.0 18290.0 22925.0 23533.0 17929.0 21757.0 22944.0 15346.0 20178.0 True False 22214.632507403745 26565.346817458 16786.26680144171 24610.980975558137 22148.835207658136 17162.21846454031 22883.47100218141 24010.06200119001 13617.57187945592 23665.740414505064 0.9386831816083001 1.1225233756546966 0.7093066393626617 1.039941305215776 0.9359029052005828 0.7251925426352326 0.9669450691750092 1.0145493688620832 0.5754128812766627 1.0 14.530512438985733 -5.2421961213335955 24.986189260214182 0.8780101055380332 1.0306032601813833 0.14870550922443115 0.15208057330286964 1589.8053988258184 2064257.570243235 0.03688025542269393 0.09724699536481544 5.7253742267984435e-06 5.2421961213335955 0.1525931546433501 DEREDITHTYK ddPTM_PC-9_AZD4547_30min_R2 2 DEREDITHTYK 11 1 P21980;P21980-2 P21980 TGM2 Protein-glutamine gamma-glutamyltransferase 2 0 ; 77.744 0.008633799999999999 13588900.0 121209.0 142411.0 143982.0 113722.0 122674.0 165089.0 157126.0 182775.0 154552.0 143701.0 False True 159750.94069617995 188442.57075110957 142072.70460383248 87505.14988738552 105642.83260737604 154765.9587322391 171109.90960660533 154531.32350166768 162721.3031958386 138670.0717291801 1.1520217643513617 1.358927477293977 1.0245376153067667 0.6310312585565062 0.7618286432684219 1.1160732579304777 1.2339353940825788 1.1143812184900594 1.1734421217696496 1.0 17.081296928090353 -9.61198076046135 16.201698419596767 1.0000000149668216 1.0570367975905348 0.007655613873082112 0.205295371626661 0.0 0.0 0.2253095726772007 0.054645598035933975 2.4435388007142204e-10 9.61198076046135 0.057036782623713256 DEREDITHTYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DEREDITHTYK 11 1 P21980;P21980-2 P21980 TGM2 Protein-glutamine gamma-glutamyltransferase 2 0 ; 97.81299999999999 0.0023587 9658000.0 78580.0 108947.0 100453.0 93498.0 95193.0 64577.0 99963.0 62020.0 64313.0 60590.0 False True 91882.0419742548 119762.53815436026 102848.18049012397 88259.61018460567 76540.61499866833 61190.46843868859 90493.78097055275 60392.04071562184 65253.45595675762 71574.48736982401 1.2837261620820564 1.6732573652333618 1.4369391143342651 1.2331155056489604 1.0693840474635108 0.8549201075310342 1.2643301306927022 0.8437649075092543 0.9116859701641209 1.0 16.127157811953104 -6.022113818150311 1.9078242146323385 0.9829121118608309 1.4948487884174726 0.6947038895622378 0.1419634218864496 0.18241882917814323 1.3302883596477646 0.04566042299788106 0.07218771502335201 9.503556956197173e-07 6.022113818150311 0.5119366765566417 DESANQEEPEAR ddPTM_PC-9_Lapatinib_30min_R1 2 DESANQEEPEAR 12 0 K7EM16;P50552 K7EM16 VASP Vasodilator-stimulated phosphoprotein 0 ; 174.24 0.00088353 4693300.0 14340.7 16259.9 17551.3 11790.7 17044.8 17683.0 13357.0 15267.4 16514.9 14095.099999999999 False True 14136.198988237707 16222.25120055527 16108.299863977249 12657.827410622174 16042.258375366135 16926.739311086316 14048.560103697067 15976.779140383922 14654.818052393244 16531.419254459805 0.8551110325523974 0.9812981541907766 0.9744051382419324 0.7656830436507971 0.9704102308722401 1.0239132557550896 0.8498096798257102 0.9664493347159983 0.8864827530424954 1.0 14.012922967668803 DETEFYLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DETEFYLGK 9 0 C9K025;P18077;F8WBS5;F8WB72 C9K025 RPL35A 60S ribosomal protein L35a 0 ; 120.15 0.0078057000000000005 7579500.0 57101.0 66910.0 71990.0 61065.0 80757.0 54764.0 77200.0 68041.0 61835.0 53312.0 False True 66767.07150384226 73552.38260721504 73706.51462359536 57643.72602540114 64933.24556897519 51892.07943348784 69887.0571204015 66254.99584539875 62739.21989467309 62977.04358244024 1.0601811026019454 1.1679237135184208 1.1703711452747012 0.9153133069821306 1.0310621438425285 0.8239840500857808 1.1097227361731532 1.052049954657962 0.9962236447721491 1.0 15.942538412204346 -5.750944052769855 24.99995622233253 0.9917452634208265 1.1363351876566592 0.4124605593564792 0.0781861758401206 209.7802923466506 499693.8803522567 0.021470112013469544 0.03668106276297655 1.7744180524819808e-06 5.750944052769855 0.14458992423583272 DETEFYLGK ddPTM_PC-9_Lapatinib_30min_R1 4 DETEFYLGK 9 0 C9K025;P18077;F8WBS5;F8WB72 C9K025 RPL35A 60S ribosomal protein L35a 0 ;;; 144.12 0.0026095 35209500.0 111861.0 111789.0 125345.0 110976.0 124613.0 111677.0 118756.0 104601.0 117349.0 112455.0 False True 110265.84162720513 111530.15943879595 115039.6179456925 119137.54524508346 117283.50833858423 106900.83504180207 124904.60460242936 109461.14432472456 104131.91988024724 131892.69691313122 0.836026893132906 0.8456128508180654 0.8722212877446982 0.903291448529188 0.889234287292123 0.810513679254056 0.9470168366084405 0.8299257418082762 0.7895199834213101 1.0 17.00900515715437 -11.664206097717239 2.4969004784386595 1.3136920380319153 0.8608207399679392 0.47952256760699197 0.0442560111939844 11122606.393155597 1768682.1131933578 19911391.73734359 0.010960779878719273 2.166675648561008e-12 11.664206097717239 -0.4528712980639761 DEVQEVVFVPAGT(ph)HTPGSR ddPTM_PC-9_AZD4547_30min_R2 1 DEVQEVVFVPAGTHTPGSR 19 0 J3KS57;J3KT79;J3QR84;J3QRJ1;J3QL71;Q96FV2-2;Q96FV2 J3KS57 SCRN2 Secernin-2 1 DEVQEVVFVPAGT(0.455)HT(0.455)PGS(0.089)R 94.01899999999999 0.0016465999999999998 2996800.0 11147.0 9755.8 14920.0 14157.0 14264.0 14423.0 14791.0 17914.0 12677.0 14286.0 True False 14691.514127996448 12909.171564933022 14722.151051445186 10893.322373469651 12283.689814562273 13521.127529969213 16107.37034603626 15145.80292276774 13347.080339391561 13785.851488319977 1.065695081688918 0.9364072705897261 1.0679174270750331 0.7901813234169095 0.8910359889608265 0.9807974169332195 1.1683986556567205 1.0986483450514448 0.9681723577756395 1.0 13.750900758253255 -7.0171023608396 23.360075570631764 1.0681073505017955 0.9460025240496223 0.24053391443850136 0.09066416027006031 424.7411853855419 580151.9011333289 0.03490055239954046 0.027750193088301643 9.613856583244166e-08 7.0171023608396 -0.12210482645217324 DEVQEVVFVPAGT(ph)HTPGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DEVQEVVFVPAGTHTPGSR 19 0 J3KS57;J3KT79;J3QR84;J3QRJ1;J3QL71;Q96FV2-2;Q96FV2 J3KS57 SCRN2 Secernin-2 1 DEVQEVVFVPAGT(0.412)HT(0.412)PGS(0.175)R 92.428 0.0018428000000000001 4278400.0 11389.0 13561.0 18572.0 18629.0 20106.0 17748.0 16671.0 15156.0 14138.0 14961.0 True False 13316.932756996539 14907.246458473226 19014.826914702215 17585.277526032878 16166.373632128652 16817.263636431635 15091.802192412046 14758.171059109398 14344.741503531783 17673.310868789154 0.7535052631544028 0.8434891780690191 1.0759063231486614 0.9950188539425433 0.9147337333763684 0.9515627129114054 0.8539318017126026 0.8350541202312094 0.8116612450281977 1.0 14.109284715225067 -7.269934837602073 23.744348073521586 0.8614162941866161 0.9287180126796266 0.0475387344294409 0.09336653308385644 836.6899110805297 2338488.035598908 0.040712606742975006 0.027991401816985707 5.371123797221241e-08 7.269934837602073 0.06730171849301048 DEVQEVVFVPAGTHT(ph)PGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DEVQEVVFVPAGTHTPGSR 19 0 J3KS57;J3KT79;J3QR84;J3QRJ1;J3QL71;Q96FV2-2;Q96FV2 J3KS57 SCRN2 Secernin-2 1 DEVQEVVFVPAGT(0.163)HT(0.419)PGS(0.419)R 77.23100000000001 0.007292900000000001 4318200.0 9831.2 12717.0 13422.0 11503.0 16363.0 14041.0 14196.0 11600.0 9402.2 11805.0 True False 11495.427984949021 13979.45971627491 13742.031383218451 10858.524203229172 13156.787612778344 13304.665242232168 12851.252109860332 11295.512291215946 9539.689387785156 13945.153051671416 0.824331432029082 1.002460113881603 0.9854342460279689 0.7786593781362413 0.9434667058889984 0.9540709372592736 0.9215569067074547 0.8099955769120875 0.6840863884704201 1.0 13.767476147954802 -7.762179139421101 24.484278451456042 0.8102807043870722 0.9190011822616468 0.12609342612749685 0.09684544840588823 24.06211086874127 796251.5431627629 0.04767308084961852 0.025032865950397224 1.7291029851958277e-08 7.762179139421101 0.10872047787457462 DEVQEVVFVPAGTHT(ph)PGSR ddPTM_PC-9_Lapatinib_30min_R1 2 DEVQEVVFVPAGTHTPGSR 19 0 J3KS57;J3KT79;J3QR84;J3QRJ1;J3QL71;Q96FV2-2;Q96FV2 J3KS57 SCRN2 Secernin-2 1 DEVQEVVFVPAGT(0.258)HT(0.702)PGS(0.04)R;DEVQEVVFVPAGT(0.191)HT(0.582)PGS(0.227)R 108.79 0.00037086 5821700.0 33800.0 39704.0 44074.0 42978.0 42227.0 45733.0 38267.0 40973.0 46670.0 33946.0 True False 33318.00580183913 39612.067827406485 40450.40585055997 46138.74549040515 39743.29088147621 43777.10619882994 40248.27801813097 42876.75515929037 41413.53314311274 39813.52086979822 0.8368515286753634 0.9949400847252231 1.0159967007902804 1.1588712699208956 0.9982360266867207 1.0995537506465152 1.010919836749795 1.0769395477358008 1.0401876608337912 1.0 15.280970839946026 -4.681614381014658 1.7633783104805454 1.0556526227282301 0.723045548790477 0.6432370337244563 0.047896164376662775 0.6941724892420449 1.7933924019801988 0.012302763514492525 0.422112160911637 2.0815441125446853e-05 4.681614381014658 -0.33260707393775313 DEVQEVVFVPAGTHTPGS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 DEVQEVVFVPAGTHTPGSR 19 0 J3KS57;J3KT79;J3QR84;J3QRJ1;J3QL71;Q96FV2-2;Q96FV2 J3KS57 SCRN2 Secernin-2 1 DEVQEVVFVPAGT(0.181)HT(0.301)PGS(0.518)R 70.593 0.0039186 2726600.0 11361.0 10497.0 16400.0 16648.0 15783.0 16795.0 16181.0 21699.0 15849.0 15125.0 True False 14973.561676519928 13889.94996997703 16182.525284430367 12810.060809036006 13591.802884410861 15744.805994996397 17621.07765324946 18345.91814341505 16686.745783625214 14595.478353691704 1.0259041405609426 0.9516611674781991 1.1087355201576687 0.8776732422610798 0.9312338078301505 1.0787454589327652 1.2072970290002505 1.2569590183232828 1.1432818698542042 1.0 13.833233874198447 -6.99830945462003 4.25916670104431 1.1713856319692115 0.9797982214224299 0.4768922394057854 0.08448275794609623 0.16422757692569867 7.199882039576182 0.03166097129050308 0.02615266701019165 1.0039002106941411e-07 6.99830945462003 -0.19158741054678163 DEVVS(ph)PLPSALQGPSGSLSAPPAASVISAPPSSSSR ddPTM_PC-9_AZD4547_30min_R2 1 DEVVSPLPSALQGPSGSLSAPPAASVISAPPSSSSR 36 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 DEVVS(0.885)PLPS(0.096)ALQGPS(0.009)GS(0.009)LS(0.002)APPAASVISAPPSSSSR 58.332 0.00019309 10261000.0 13386.0 16097.0 18851.0 24652.0 22725.0 23950.0 16759.0 23854.0 20794.0 19404.0 True False 17642.469553903335 21300.04045600841 18601.023422975413 18968.862269603298 19570.02601205326 22452.402713912692 18250.518533515093 20167.912410388613 21893.128388207635 18724.671866117937 0.9422044711943479 1.1375387834993558 0.9933964961294588 1.0130411045507943 1.045146539922282 1.1990812375484154 0.9746776159287032 1.0770769471737554 1.1692129263863353 1.0 14.192652816456583 -6.538133406899386 24.994159307937714 1.0864515755747435 1.0279790630564272 0.12451750240582415 0.07769798457422486 535.2494658718078 876979.2725620372 0.024784276194057573 0.024793084547319516 2.89645371624299e-07 6.538133406899386 -0.05847251251831631 DEVVS(ph)PLPSALQGPSGSLSAPPAASVISAPPSSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DEVVSPLPSALQGPSGSLSAPPAASVISAPPSSSSR 36 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 DEVVS(0.958)PLPS(0.03)ALQGPS(0.006)GS(0.004)LS(0.002)APPAASVISAPPSSSSR;DEVVS(0.974)PLPS(0.021)ALQGPS(0.003)GS(0.001)LSAPPAASVISAPPSSSSR 61.577 8.9088e-05 8846200.0 13215.0 16120.7 17808.6 20631.8 18006.7 18046.2 19294.5 13140.9 14850.1 15181.7 True False 15452.038491852607 17721.056558005253 18233.224563491596 19475.867135198103 14478.41639717751 17099.825503480533 17466.785279916876 12795.965298934447 15067.254618870935 17934.022031728917 0.8616047456903322 0.988125057873416 1.016683515344931 1.0859731911080153 0.8073156356985767 0.953485251285377 0.9739469065564097 0.7135022626991198 0.8401492198578718 1.0 14.130411454733729 -6.975383197212351 1.1284307749086002 0.8535241502143136 0.9761100303098613 0.11575650233092283 0.10168149779166201 0.857652925818368 2.2542627402430058 0.06102612231567753 0.044847543433489206 1.0583195110182017e-07 6.975383197212351 0.12258588009554772 DEVVS(ph)PLPSALQGPSGSLSAPPAASVISAPPSSSSR ddPTM_PC-9_Lapatinib_30min_R1 2 DEVVSPLPSALQGPSGSLSAPPAASVISAPPSSSSR 36 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 DEVVS(0.981)PLPS(0.014)ALQGPS(0.003)GS(0.002)LSAPPAASVISAPPSSSSR;DEVVS(0.865)PLPS(0.037)ALQGPS(0.021)GS(0.051)LS(0.026)APPAASVISAPPSSSSR 75.19800000000001 1.2854e-08 19618500.0 45032.7 42136.0 44093.9 39089.7 41733.3 43304.5 44006.6 54663.1 53427.4 33769.6 True False 44390.52544001426 42038.43668082815 40468.66974937618 41964.48693741658 39278.6293448247 41452.46748271995 46285.04642205248 57202.94718345755 47409.84359653613 39606.63036483645 1.1207852077066633 1.0613989701620945 1.0217650271330598 1.0595318650150427 0.9917185325540101 1.046604245321568 1.1686186377305467 1.4442770479723381 1.1970178518046193 1.0 15.273454345050242 -7.413642909684962 4.240146213763025 1.2508767109561436 1.0480980894795473 0.31236499830853315 0.10672903813498531 0.2147103803615533 6.493695647809627 0.04520364644680688 0.02921214078637343 3.857954401978086e-08 7.413642909684962 -0.2027786214765963 DEWGLVAPIS(ph)PGPLTPMR ddPTM_PC-9_AZD4547_30min_R2 1 DEWGLVAPISPGPLTPMR 18 0 A0A669KB77;P11137-3;P11137;E7EV03 A0A669KB77 MAP2 Microtubule-associated protein 2 1 DEWGLVAPIS(0.894)PGPLT(0.106)PMR 69.229 0.0098675 2922100.0 42774.0 44812.0 52131.0 70762.0 65099.0 62721.0 48835.0 70745.0 52493.0 53376.0 True False 56375.24224552972 59296.60265357818 51439.70887820968 54448.91416200182 56061.12754053491 58799.04595487756 53181.22039406939 59812.98580837353 55267.67281341652 51507.322486389945 1.0945092760437325 1.1512266565447358 0.9986873010493192 1.0571101648001437 1.0884108284865368 1.1415667349125815 1.0324982512558627 1.1612520884613684 1.0730061308859569 1.0 15.652489925706428 DEWGLVAPIS(ph)PGPLTPMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DEWGLVAPISPGPLTPMR 18 0 A0A669KB77;P11137-3;P11137;E7EV03 A0A669KB77 MAP2 Microtubule-associated protein 2 1 DEWGLVAPIS(0.999)PGPLT(0.001)PMR;DEWGLVAPIS(0.999)PGPLT(0.001)PMR 92.236 0.0010193 6146700.0 16584.6 21129.1 22737.0 32343.0 38567.0 43086.0 39513.0 35819.0 32242.0 31674.0 True False 19392.045219218962 23226.657410642758 23279.136310552694 30530.926567420767 31010.073205526027 40826.49431143189 35770.042590653095 34878.78920336761 32713.478254128735 37416.24546875394 0.5182787576966569 0.6207639788454773 0.6221665487520106 0.8159804968383838 0.8287863417889518 1.0911435340439442 0.9560029912815389 0.9321830335033122 0.8743121562383255 1.0 15.191377178230582 -5.91505135120866 1.3139408669842743 0.9621046665968239 0.5549224119165688 0.8643847062203739 0.06479250509502159 0.15745618970189598 0.5509675024906723 0.02366466492066086 0.04835576357181927 1.216042206673335e-06 5.91505135120866 -0.40718225468025515 DEWGLVAPIS(ph)PGPLTPMR ddPTM_PC-9_Lapatinib_30min_R1 1 DEWGLVAPISPGPLTPMR 18 0 A0A669KB77;P11137-3;P11137;E7EV03 A0A669KB77 MAP2 Microtubule-associated protein 2 1 DEWGLVAPIS(0.964)PGPLT(0.036)PMR 74.33800000000001 0.0055773 2236600.0 9927.6 14965.0 15493.0 11455.0 19778.0 21133.0 17276.0 14033.0 17284.0 14327.0 True False 9786.030603501134 14930.349461946858 14219.225344709475 12297.438912759795 18614.69692504408 20229.19085342911 18170.466747882783 14685.024409985173 15337.293911411192 16803.402860472484 0.5823838590766232 0.8885313043983665 0.8462110599132332 0.7318421759492357 1.1077932892290763 1.2038746569015069 1.081356371608879 0.8739315799259635 0.9127492829139926 1.0 14.03646580260136 -6.257721483038053 24.994597433878546 1.034913909950581 0.7772605316139686 0.5583003929027093 0.11629688303895111 279.32065663998304 1877809.5820173447 0.03794472142397932 0.04706785533125406 5.524316050665889e-07 6.257721483038053 -0.2576533783366125 DEYRQDYDAGR ddPTM_PC-9_AZD4547_30min_R2 2 DEYRQDYDAGR 11 1 P52298-3;P52298;C9JQX9;B3KSB0;P52298-2 P52298-3 NCBP2 Nuclear cap-binding protein subunit 2 0 ; 118.23 0.0014049000000000002 28691000.0 54424.0 38618.0 83849.0 104670.0 81782.0 80471.0 57099.0 93324.0 69893.0 65870.0 False True 71729.6999104762 51100.51328384994 82737.1074740367 80539.94863537958 70427.98096007656 75439.13564890464 62180.700384580094 78902.92017217692 73587.40129061244 63563.91134926762 1.128465797460758 0.8039233615292417 1.3016365059635369 1.2670703694244512 1.1079868979914187 1.1868233726899793 0.9782390520764663 1.2413163145141481 1.1576915222580983 1.0 15.955920281935269 -5.265289496653278 24.999209550717495 1.1608474294978484 0.9661945846073499 0.2709113143134083 0.12366919978060903 374.7765740101293 2433481.1526678363 0.031130481659820727 0.0689964050715204 5.428883265534355e-06 5.265289496653278 -0.1946528448904985 DEYRQDYDAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DEYRQDYDAGR 11 1 P52298-3;P52298;C9JQX9;B3KSB0;P52298-2 P52298-3 NCBP2 Nuclear cap-binding protein subunit 2 0 ; 119.22 0.0012783 22246000.0 89433.0 78646.0 86958.0 94772.0 109454.0 108338.0 100416.0 85536.0 84910.0 74528.0 False True 104572.24051773369 86453.45512669324 89031.40851005154 89462.23209496961 88007.27442211316 102656.564561851 90903.86953111675 83290.77063288353 86151.64811606206 88039.33643667641 1.187789966964924 0.9819866735237851 1.0112685092088203 1.0161620443302255 0.9996358217149182 1.1660306485350245 1.032536968250558 0.9460631350031999 0.9785585807774448 1.0 16.42586065104966 -7.625025230400194 6.007583377004814 0.9727535780494766 1.0537228859986407 0.2479411040029813 0.06589083818140629 0.3186501765690434 16.041389577507026 0.03188205258822516 0.01811643964381577 2.3712359443678944e-08 7.625025230400194 0.08096930794916413 DEYRQDYDAGR ddPTM_PC-9_Lapatinib_30min_R1 2 DEYRQDYDAGR 11 1 P52298-3;P52298;C9JQX9;B3KSB0;P52298-2 P52298-3 NCBP2 Nuclear cap-binding protein subunit 2 0 ; 103.31 0.0038333 33601000.0 125564.0 96225.0 149275.0 89925.0 117924.0 126537.0 90309.0 112830.0 124155.0 85687.0 False True 123773.43433438255 96002.19692454659 137002.18571816376 96538.3844810059 110987.94216750424 121125.30748215398 94984.75813466925 118072.49370616564 110171.35648988989 100497.88377924959 1.23160239479529 0.9552658555022105 1.3632345335658842 0.9606011674142213 1.104380888370712 1.2052523190260793 0.9451418732687914 1.1748754229046243 1.0962554866517262 1.0 16.61680559680294 -8.027627948451608 0.01382548109481418 1.5613136978031065e-06 2.169442791959219 0.08310726905002874 0.12759310650223465 1519.9012034254617 21.225825959718975 1667.3140686255324 1658.2280269944265 9.38365542010542e-09 8.027627948451608 2.1694412306455213 DFAKS(ph)IT(ph)RPFSVYFNPYTQS(ph)IEILK ddPTM_PC-9_AZD4547_30min_R2 1 DFAKSITRPFSVYFNPYTQSIEILK 25 2 Q8IWU9;Q8IWU9-2 Q8IWU9 TPH2 Tryptophan 5-hydroxylase 2 3 DFAKS(0.994)IT(0.942)RPFS(0.1)VY(0.085)FNPY(0.087)T(0.093)QS(0.698)IEILK 51.833999999999996 0.037639 0.0 2344.2 2272.7 4144.4 5670.6 2504.2 2375.2 3668.0 4781.1 3321.7 3431.2 True False 3089.606837610952 3007.3058299291974 4089.442548097144 4363.330779896661 2156.5350556384506 2226.678368521311 3994.4448941424503 4042.2908537481735 3497.2782806150476 3311.0747323759992 0.9331129881788793 0.9082567060548283 1.2350801110316814 1.3177989422079794 0.6513096894345659 0.6724941441969403 1.206389229178186 1.2208395099700633 1.0562365888085619 1.0 11.69308385800996 -10.541094519387618 8.786978873690197 1.0000036148199682 1.0240212282393402 0.0008747728096935026 0.22091524736215068 3.2797518096787687e-10 3.196689323273222e-18 0.23200993163483533 0.056270673783691695 2.8767722489565716e-11 10.541094519387618 0.02401761341937192 DFAYRS(ph)AFIVHK ddPTM_PC-9_Lapatinib_30min_R1 1 DFAYRSAFIVHK 12 1 P59923 P59923 ZNF445 Zinc finger protein 445 1 DFAY(0.036)RS(0.964)AFIVHK 57.794 0.033471 27686000.0 126340.0 104190.0 146110.0 124970.0 157690.0 142860.0 147850.0 92053.0 145000.0 87965.0 True False 124538.36843208168 103948.75445641426 134097.3998009105 134160.71068769932 148414.9842304684 136750.21082292555 155504.9495643941 96330.1184359982 128668.57308230888 103169.63304400501 1.2071223358811625 1.0075518482466341 1.299775872457682 1.3003895306138742 1.4385529913357826 1.3254889717849185 1.5072744273314076 0.9337061264423656 1.2471554786613208 1.0 16.65465886473533 -7.774260881358832 24.999674377711553 1.0678231506878855 1.2934702980640485 0.3584871245062723 0.14554277141940486 296.0482963219899 577233.327232229 0.08321240710533294 0.04038212355244102 1.6816635797202777e-08 7.774260881358832 0.22564714737616298 DFFQSYGNVVELR ddPTM_PC-9_Lapatinib_30min_R1 2 DFFQSYGNVVELR 13 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 0 ; 118.9 0.001088 7770400.0 31528.0 25707.0 25269.3 26362.0 28037.0 27123.0 25851.0 23688.0 28398.0 23434.6 False True 31078.4049384729 25647.477020933384 23191.75569631881 28300.74942105403 26387.91878286283 25963.012516801107 27189.43829008555 24788.63095729555 25199.51819580277 27485.23938535833 1.130730735240701 0.933136388639062 0.8437894744578174 1.0296708361990885 0.9600760034464152 0.9446165686529138 0.9892378199394415 0.9018888505843143 0.9168382287849679 1.0 14.746369424272235 -4.759297708731399 24.999354404380835 0.9445950555305548 1.1307309738309965 0.5452139672514664 0.050425751998097526 43.79458709685004 511084.7458908855 0.012529803307501673 0.08051428219046051 1.740613274477717e-05 4.759297708731399 0.18613591830044174 DFGNHQVT(ph)GK ddPTM_PC-9_AZD4547_30min_R2 1 DFGNHQVTGK 10 0 A0A075B785;A0A2R8Y566;Q9P260;Q9P260-2 A0A075B785 KIAA1468 LisH domain and HEAT repeat-containing protein KIAA1468 1 DFGNHQVT(1)GK 88.94200000000001 0.023634 6735800.0 11684.0 10002.0 17275.0 24224.0 21216.0 18775.0 15546.0 20719.0 11806.0 19454.0 True False 15399.268957702572 13234.950900229616 17045.922212715526 18639.531057069216 18270.524614817255 17600.99628199211 16929.56388340745 17517.354625255364 12430.041057573311 18772.92138133675 0.8202915595764375 0.7050022013828519 0.9080058381143526 0.9928945356155305 0.9732382213554169 0.9375736426132526 0.9018076376880857 0.9331182009141307 0.6621260913568165 1.0 14.196365554726974 -5.282229034688932 19.213314458448757 0.9166047559390091 0.7626473988504657 0.2915947250581594 0.09401741524694834 44.66863055074645 41282.6882302457 0.024527261284303336 0.05131729611576457 5.221207645809298e-06 5.282229034688932 -0.1539573570885434 DFHKDEVR ddPTM_PC-9_AZD4547_30min_R2 1 DFHKDEVR 8 1 P49915-2;P49915 P49915-2 GMPS GMP synthase [glutamine-hydrolyzing] 0 71.877 0.015413999999999999 2492300.0 14385.0 14623.0 12602.0 13223.0 11971.0 15661.0 15439.0 16570.0 13457.0 12138.0 False True 18959.13077341247 19349.59878164942 12434.889245999471 10174.641643313502 10309.033284501193 14681.715194262493 16813.041090693932 14009.487240720178 14168.309546989996 11713.052314519668 1.6186328093071403 1.651968954126789 1.061626714548607 0.86865843079185 0.8801320960311914 1.2534491266689578 1.43541074002139 1.1960577708129774 1.209617200243079 1.0 13.515829457541205 -5.258646272802703 24.95533198038725 1.1195915795844362 1.635300940452697 0.6174128140462525 0.16435854320256757 172.0515088912215 1537192.6601116555 0.04884718936179084 0.11781908487303377 5.512565048474214e-06 5.258646272802703 0.5157093608682608 DFIHTASISFLT(ph)PLR ddPTM_PC-9_AZD4547_30min_R2 1 DFIHTASISFLTPLR 15 0 B7ZC39;B7ZC38;Q9NR46;Q9NR46-2 B7ZC39 SH3GLB2 Endophilin-B2 1 DFIHT(0.065)AS(0.026)IS(0.07)FLT(0.838)PLR 91.62200000000001 0.008068500000000001 2657800.0 12150.0 6439.2 17508.0 21182.0 18068.0 15641.0 12166.0 18036.0 12721.0 15159.0 True False 16013.447264300425 8520.54547458093 17275.832480476023 16298.817158637714 15559.570076381886 14662.965797424144 13248.750431335078 15248.95062604883 13393.406089563787 14628.28802404049 1.0946904544115845 0.5824704477091273 1.1809879906715326 1.1141985399693959 1.0636630924145671 1.0023705968413161 0.9056938453468891 1.0424289295499465 0.9155826073121293 1.0 13.836473317600873 -5.282731391620822 24.99531760375981 1.0286832674300144 0.8385803103238731 0.2298865286692866 0.13875881925694117 970.7964677695126 1139645.122810488 0.034867646599534695 0.07269479655882428 5.215171664321883e-06 5.282731391620822 -0.19010295710614122 DFQDYMEPEEGCQGS(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 7 DFQDYMEPEEGCQGSPQR 18 0 O43237;O43237-2;H3BUM4;B4E2E0 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 DFQDY(0.001)MEPEEGCQGS(0.999)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDY(0.1)MEPEEGCQGS(0.9)PQR;DFQDYMEPEEGCQGS(1)PQR 174.72 2.1943e-08 177711300.0 196241.0 194438.0 254487.0 302329.0 284941.0 264909.0 236402.0 316434.0 244514.0 231256.0 True False 258641.55593362846 257286.28105767313 251112.33610114796 232631.71998648782 245381.86058967983 248344.1983523971 257441.32002864304 267536.3962299371 257438.5108547757 223159.7978288483 1.158997088409234 1.1529239744830655 1.1252579476422442 1.042444572229376 1.0995791490090643 1.1128536625708179 1.1536187186640439 1.198855702652694 1.1536061304922733 1.0 17.767717623929478 -7.247703996031244 21.986621375643796 1.143091442507982 1.113471574299351 0.0 0.05728210519177995 535.9496614937947 857912.7464070166 0.021998229479603476 0.01690333818225463 5.6532215259883465e-08 7.247703996031244 -0.02961986820863083 DFQDYMEPEEGCQGS(ph)PQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DFQDYMEPEEGCQGSPQR 18 0 O43237;O43237-2;H3BUM4;B4E2E0 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 DFQDY(0.018)MEPEEGCQGS(0.982)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR 147.49 3.5916e-05 142879000.0 263053.0 315109.0 342954.0 309878.0 363031.0 298402.0 312675.0 309962.0 287000.0 226692.0 True False 307582.6773664248 346390.939037168 351131.3240202871 292516.5402980308 291897.6815898394 282753.2738133016 283056.1604290352 301825.8259318857 291196.83204934443 267789.465107116 1.1485988712938784 1.2935196644073035 1.3112215743058986 1.0923377444330158 1.0900267546861118 1.0558790044268547 1.057010066903911 1.1271011942577918 1.087409588472293 1.0 18.030739680294424 -5.8141565172998595 7.720066937588466 1.0768649336682812 1.2551041535763323 0.7215345578776831 0.05071117951229447 0.11647719305016625 14.649146259793458 0.014182890321776848 0.02124434353648582 1.5340640150795405e-06 5.8141565172998595 0.17823921990805114 DFQDYMEPEEGCQGS(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 15 DFQDYMEPEEGCQGSPQR 18 0 O43237;O43237-2;H3BUM4;B4E2E0 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDY(0.001)MEPEEGCQGS(0.999)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDY(0.002)MEPEEGCQGS(0.998)PQR;DFQDYMEPEEGCQGS(1)PQR 213.01 9.857899999999999e-68 183965400.0 314277.6 422286.2 471260.0 415949.1 470558.0 433479.5 424214.3 443168.5 461539.2 372136.9 True False 309795.9437925473 421308.4222490871 432514.8219162065 446539.38437952247 442880.70359262236 414940.59227506845 446178.04075748904 463759.7263761501 409555.79507276043 436460.26732374897 0.7097918573255899 0.9652847092644452 0.9909603560669227 1.0230928627652085 1.0147102422592593 0.9506949964068137 1.022264966965554 1.0625474094578957 0.9383575682250319 1.0 18.73549080012649 -4.742008597100601 3.238416780546593 1.0022034390422934 0.6520953890452363 0.8666493663737842 0.03396464818094802 0.13095947007475156 1.9438652255055906 0.008519540955695808 0.12268234259716543 1.8113042364908278e-05 4.742008597100601 -0.350108049997057 DFQDYMEPEEGCQGS(ph)PQRR ddPTM_PC-9_AZD4547_30min_R2 6 DFQDYMEPEEGCQGSPQRR 19 1 O43237;O43237-2;H3BUM4;B4E2E0 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 DFQDY(0.005)MEPEEGCQGS(0.995)PQRR;DFQDY(0.002)MEPEEGCQGS(0.998)PQRR;DFQDYMEPEEGCQGS(1)PQRR;DFQDYMEPEEGCQGS(1)PQRR;DFQDYMEPEEGCQGS(1)PQRR;DFQDYMEPEEGCQGS(1)PQRR 94.359 0.00035174 242330300.0 135699.0 124482.7 181731.0 238876.0 217401.0 195632.0 151716.1 198141.0 166019.2 171971.0 True False 178848.45928545736 164719.29838312467 179321.12819907398 183806.8287974102 187218.62376441804 183399.10011391054 165218.53898696997 167522.86127722004 174794.63597708565 165950.34763389887 1.077722715471575 0.9925818218019645 1.0805709705090358 1.1076013483436884 1.1281604795275202 1.1051444165607 0.9955901951555816 1.0094758080699553 1.0532947864785318 1.0 17.340392126023417 -7.263691824219289 24.982030594437898 1.0153798469660444 1.081102721997289 0.4474771239644083 0.03666448118796504 219.90008421803154 2438908.350260279 0.01660998955602387 0.011843537585953608 5.448891695669863e-08 7.263691824219289 0.06572287503124463 DFQDYMEPEEGCQGS(ph)PQRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DFQDYMEPEEGCQGSPQRR 19 1 O43237;O43237-2;H3BUM4;B4E2E0 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 DFQDY(0.079)MEPEEGCQGS(0.921)PQRR;DFQDY(0.061)MEPEEGCQGS(0.939)PQRR;DFQDY(0.009)MEPEEGCQGS(0.991)PQRR 94.61 0.00028073 257092000.0 127458.0 118471.0 150379.0 168739.0 166301.0 147540.0 153032.0 132475.0 133774.0 117018.0 True False 149034.12198975054 130232.01793243726 153964.60567553356 159285.10088921952 133715.5128517172 139802.74267067394 138535.7011042652 128997.67161886468 135730.19167445638 138232.43708602202 1.0781414632587765 0.9421234312131377 1.1138095292331525 1.152299013509372 0.9673237025294292 1.01135989220587 1.0021938701554864 0.9331939329015045 0.9818982760897972 1.0 17.076736667095943 -6.307375046176792 24.995348393346326 0.981732814041382 1.0653610660821884 0.3898982154736744 0.05426795112871442 500.3334581109881 272249.0807764937 0.01780586015228322 0.020190010018428156 4.927480948667522e-07 6.307375046176792 0.08362825204080637 DFQDYMEPEEGCQGS(ph)PQRR ddPTM_PC-9_Lapatinib_30min_R1 10 DFQDYMEPEEGCQGSPQRR 19 1 O43237;O43237-2;H3BUM4;B4E2E0 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 DFQDY(0.011)MEPEEGCQGS(0.989)PQRR;DFQDY(0.172)MEPEEGCQGS(0.828)PQRR;DFQDY(0.002)MEPEEGCQGS(0.998)PQRR;DFQDY(0.01)MEPEEGCQGS(0.99)PQRR;DFQDY(0.003)MEPEEGCQGS(0.997)PQRR;DFQDY(0.001)MEPEEGCQGS(0.999)PQRR;DFQDYMEPEEGCQGS(1)PQRR;DFQDYMEPEEGCQGS(1)PQRR;DFQDYMEPEEGCQGS(1)PQRR;DFQDYMEPEEGCQGS(1)PQRR 119.18 2.3666e-05 359188200.0 341943.3 390534.9 473586.0 376220.0 431850.5 444638.3 357415.2 371317.5 411807.0 331262.7 True False 337067.1258372784 389630.6404334436 434649.5871748265 403888.4738331285 406449.9026407499 425622.15641150204 375920.4102099952 388570.26661117835 365424.95914004336 388521.0163151974 0.8675647176929657 1.0028560208370967 1.118728637377511 1.0395537355061995 1.0461465032074537 1.095493264297974 0.9675677619071715 1.0001267635312192 0.9405539051807257 1.0 18.567633115061156 -9.7992433211551 7.6313865087940345 0.9999999993197066 1.0148896063319142 0.0 0.06978347358874129 0.0 0.0 0.06990636998140817 0.016954785263784973 1.5876569864966674e-10 9.7992433211551 0.01488960701220754 DFQEYVEPGEDFPAS(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 5 DFQEYVEPGEDFPASPQR 18 0 Q9Y6G9;E9PHI6;C9JGM7 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 DFQEYVEPGEDFPAS(1)PQR;DFQEYVEPGEDFPAS(1)PQR;DFQEYVEPGEDFPAS(1)PQR;DFQEYVEPGEDFPAS(1)PQR;DFQEYVEPGEDFPAS(1)PQR 157.88 1.0333e-08 27572600.0 82098.7 91266.8 108018.8 105133.1 100678.0 115407.90000000001 97499.5 122059.2 99216.6 96718.2 True False 108204.37884095637 120767.00828045137 106586.40013376978 80896.28808520315 86700.59752877869 108191.42576897536 106176.76661844099 103197.75528138272 104460.98692129656 93332.12525672912 1.1593476366612039 1.293948980035084 1.1420119261249229 0.8667571627955685 0.9289469975133529 1.159208851950737 1.1376229387939045 1.105704547041184 1.119239346944637 1.0 16.510086126985122 -5.524833684188585 24.999987259437972 1.0497189175811144 1.2244813726635018 0.3815285611544269 0.09342570667367579 66.16661232292626 846143.4820643736 0.027914410597680028 0.04876915612415678 2.9865261089633348e-06 5.524833684188585 0.1747624550823874 DFQEYVEPGEDFPAS(ph)PQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DFQEYVEPGEDFPASPQR 18 0 Q9Y6G9;E9PHI6;C9JGM7 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 DFQEYVEPGEDFPAS(1)PQR;DFQEYVEPGEDFPAS(1)PQR;DFQEYVEPGEDFPAS(1)PQR;DFQEYVEPGEDFPAS(1)PQR;DFQEYVEPGEDFPAS(1)PQR;DFQEY(0.005)VEPGEDFPAS(0.995)PQR 222.13 1.7739e-28 62936800.0 96565.59999999999 141487.0 131821.4 117891.6 128307.0 103398.3 130260.7 110598.5 103006.7 84683.5 True False 112912.24882246244 155532.89430499246 134964.52211144366 111286.51586172392 103166.16440950631 97975.91112569575 117921.46349020017 107695.406563797 104512.9781179691 100035.94819578265 1.1287167349229228 1.5547700312751118 1.3491602223562822 1.1124652474320784 1.0312909136183468 0.9794070320995494 1.1787908808482863 1.076567059203796 1.0447542108905126 1.0 16.610159004079215 -5.796674849416008 4.104473475404409 1.0599572341298595 1.3691426403285492 0.5903428427942115 0.10864989743865221 0.13333379873020576 4.845252360665233 0.029917213849404958 0.04834737490778604 1.5970744084109402e-06 5.796674849416008 0.3091854061986896 DFQEYVEPGEDFPAS(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 6 DFQEYVEPGEDFPASPQR 18 0 Q9Y6G9;E9PHI6;C9JGM7 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 DFQEYVEPGEDFPAS(1)PQR;DFQEYVEPGEDFPAS(1)PQR;DFQEYVEPGEDFPAS(1)PQR;DFQEYVEPGEDFPAS(1)PQR;DFQEYVEPGEDFPAS(1)PQR;DFQEYVEPGEDFPAS(1)PQR 223.44 8.701199999999998e-35 55047900.0 88694.2 114820.5 113247.9 107458.29999999999 127768.3 119218.9 110981.5 127872.6 117437.9 101795.0 True False 87429.40444347572 114554.64018680065 103937.0948115359 115361.14185238024 120253.21979614264 114120.18555982971 116727.5790333499 133814.02781787683 104210.80702608859 119390.13011668884 0.7323001018427945 0.9594984114251144 0.8705668945159073 0.9662535901387261 1.0072291543581553 0.9558594621539618 0.9776987337166261 1.1208131500241305 0.8728594811332865 1.0 16.865324049563284 -3.791109463591863 0.7297357124511707 0.9920864539331051 2.917712963009303e-13 0.5214294810332514 0.0676487470181164 8.255204720928312 1.1343954398630425 0.025123919354932012 9.406646776704411 0.00016176722532006894 3.791109463591863 -0.9920864539328134 DFQEYVEPGEDFPAS(ph)PQRR ddPTM_PC-9_AZD4547_30min_R2 7 DFQEYVEPGEDFPASPQRR 19 1 Q9Y6G9;E9PHI6;C9JGM7 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 DFQEYVEPGEDFPAS(1)PQRR;DFQEYVEPGEDFPAS(1)PQRR;DFQEYVEPGEDFPAS(1)PQRR;DFQEYVEPGEDFPAS(1)PQRR;DFQEYVEPGEDFPAS(1)PQRR;DFQEYVEPGEDFPAS(1)PQRR;DFQEYVEPGEDFPAS(1)PQRR 140.67 1.9282e-05 522252300.0 1358141.7 1025373.8 1698555.9 2325386.0 1876797.6 1670456.0 1408071.4 1696779.8 1524141.5 1757972.0 True False 1790002.509497723 1356805.8285724719 1676031.9389492897 1789304.184555562 1616236.6491247131 1566002.1222493397 1533387.026804258 1434581.4700308829 1604704.5080934572 1696425.935365032 1.055161013623949 0.7998025733322206 0.9879782571165691 1.0547493688078664 0.9527304525540257 0.9231184749084681 0.9038927045608439 0.8456493384853809 0.9459325483302998 1.0 20.694067013806254 -6.756824384572553 3.8617048132272616 0.9118543111742751 0.9671347057714121 0.0779693436909561 0.07572903235080733 0.5491058965479341 17.977586794625054 0.027111596113788262 0.025402543539815997 1.750554416276643e-07 6.756824384572553 0.05528039459713707 DFQEYVEPGEDFPAS(ph)PQRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DFQEYVEPGEDFPASPQRR 19 1 Q9Y6G9;E9PHI6;C9JGM7 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 DFQEYVEPGEDFPAS(1)PQRR;DFQEYVEPGEDFPAS(1)PQRR;DFQEYVEPGEDFPAS(1)PQRR;DFQEYVEPGEDFPAS(1)PQRR;DFQEYVEPGEDFPAS(1)PQRR;DFQEYVEPGEDFPAS(1)PQRR 128.8 1.6181e-05 438521200.0 599927.6 587268.8 731331.4 775326.0 887450.1 838416.5 874968.8 973362.6 719581.7 606016.1 True False 701483.4935697891 645568.9653397126 748769.1141657779 731886.9978608066 713560.6235188473 794448.4627921052 792085.4210384596 947812.8631129242 730104.2210476716 715882.0217091908 0.9798870097267917 0.9017812233898491 1.0459392629780926 1.0223570025035738 0.9967572894416302 1.1097477499090347 1.1064468683643303 1.3239791395375333 1.0198666804126815 1.0 19.44936232349135 -6.800986491149864 2.1454938271396804 1.1391377944831869 0.9848035009829247 0.2995437841010017 0.09003314272394518 0.33632613272178663 3.1805580065855175 0.03522887564812296 0.03159899328081182 1.5812972251935335e-07 6.800986491149864 -0.15433429350026218 DFQEYVEPGEDFPAS(ph)PQRR ddPTM_PC-9_Lapatinib_30min_R1 6 DFQEYVEPGEDFPASPQRR 19 1 Q9Y6G9;E9PHI6;C9JGM7 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 DFQEYVEPGEDFPAS(1)PQRR;DFQEYVEPGEDFPAS(1)PQRR;DFQEYVEPGEDFPAS(1)PQRR;DFQEYVEPGEDFPAS(1)PQRR;DFQEYVEPGEDFPAS(1)PQRR;DFQEYVEPGEDFPAS(1)PQRR 161.56 1.8793000000000002e-06 427515700.0 297701.1 264822.3 323945.1 256038.1 307095.1 303154.0 240423.3 235383.6 287137.0 216187.6 True False 293455.82772230444 264209.1202349841 297311.5843422474 274867.99599206354 289032.36999019614 290188.81010649 252871.24207375819 246320.38136607906 254796.6073733437 253555.3386081307 1.157364026855849 1.0420175796153075 1.1725707925311795 1.0840552500330964 1.139918297823321 1.1444791961370462 0.9973019833140655 0.9714659636757511 1.0048954550593445 1.0 17.951941125107943 -7.270030808138228 23.656453514979017 0.9910379874511563 1.1208989708291102 0.7542611923115976 0.03632054870316857 145.50453468553886 400643.27747403935 0.014205123306439721 0.009760960438314826 5.3699370156665125e-08 7.270030808138228 0.12986098337795382 DFQHLIS(ph)SPLKK ddPTM_PC-9_Lapatinib_30min_R1 1 DFQHLISSPLKK 12 1 Q15361 Q15361 TTF1 Transcription termination factor 1 1 DFQHLIS(0.5)S(0.5)PLKK 50.102 0.040072 9638900.0 66567.0 79030.0 81980.0 88650.0 100900.0 86751.0 77710.0 78495.0 93219.0 87077.0 True False 65617.74237310736 78847.01089058879 75239.92085195139 95169.6167277309 94965.26037703255 83040.86195645813 81733.44356204974 82142.16426008572 82719.69458041208 102128.14342719101 0.6425040167296043 0.7720399905908428 0.7367207346287586 0.9318647488738403 0.9298637690866768 0.8131045877247289 0.8003028432639528 0.8043048811383352 0.8099598387332325 1.0 16.640020958555894 -5.0741075957187505 1.4058271706043755 0.8553399233417118 0.6323506447173897 0.4728723189523022 0.07199897369420238 0.7260188666949734 1.895145508712957 0.021998614497108954 0.19712538107218702 8.431258488928176e-06 5.0741075957187505 -0.22298927862432216 DFSASYFSGEQEVT(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 1 DFSASYFSGEQEVTPSR 17 0 P49454 P49454 CENPF Centromere protein F 1 DFSAS(0.003)YFS(0.368)GEQEVT(0.606)PS(0.023)R 92.427 0.0050076 5628000.0 12619.0 11152.0 10622.0 18449.0 15079.0 14372.0 8039.0 15371.0 13067.0 17639.0 True False 16631.57950849442 14756.665910753907 10481.145339708495 14195.868084208636 12985.541132486296 13473.316568031452 8754.455426393448 12995.76514044115 13757.694943190787 17021.463978893742 0.977094539524757 0.8669445782719902 0.6157605099481981 0.8339980686626729 0.7628921430370558 0.7915486344028976 0.5143185942906432 0.7634927968919493 0.8082556800196529 1.0 14.055067504955222 -5.016245955012303 6.050795625281996 0.7470020589123282 0.9539874898212582 0.23161470712576393 0.12239955046737314 0.1774697260934642 26.66058476845662 0.02992658917423081 0.09564980571334954 9.632833306093501e-06 5.016245955012303 0.20698543090893007 DFSASYFSGEQEVT(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DFSASYFSGEQEVTPSR 17 0 P49454 P49454 CENPF Centromere protein F 1 DFSASYFSGEQEVT(1)PSR;DFSASYFSGEQEVT(0.978)PS(0.021)R 195.28 9.9966e-12 6025300.0 17852.6 17438.6 18870.5 15586.099999999999 21736.0 18730.300000000003 18482.6 16235.3 13898.2 9351.7 True False 20874.69257507741 19169.788960307582 19320.444286769773 14712.861347817987 17476.986833181556 17748.05009519132 16731.794325563857 15809.140577722275 14101.434882188818 11047.089181983527 1.8896102159763064 1.7352796419504968 1.7489172005852087 1.3318314992706761 1.5820445137425359 1.606581589305557 1.5145885083331634 1.4310684305423262 1.276484207730174 1.0 13.431378660847102 -1.5228787474896641 0.051028554013134664 4.527616408544249e-14 4.371684027311722 0.808849769157187 0.10878053902562801 215.08675692704915 0.8308239657188045 16.52955856572465 73.59320846550807 0.02999999984738513 1.5228787474896641 4.371684027311677 DFSASYFSGEQEVT(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 2 DFSASYFSGEQEVTPSR 17 0 P49454 P49454 CENPF Centromere protein F 1 DFSASYFSGEQEVT(0.998)PS(0.001)R;DFSASYFS(0.001)GEQEVT(0.931)PS(0.068)R 103.77 0.0020366 8485200.0 31450.0 25129.0 28330.0 25512.0 23579.0 18843.5 20867.0 18363.1 20569.9 16397.9 True False 31001.517232776347 25070.815344421157 26000.81675696248 27388.23758553716 22192.129578097607 18037.60743134393 21947.391156984842 19216.316663792386 18253.101251350232 19232.2551661717 1.61195434258308 1.3035816719257711 1.351938008949478 1.4240783178517362 1.153901577654405 0.9378831174760474 1.1411761630320343 0.9991712619117414 0.9490879303357135 1.0 14.231240321961623 -6.410557511670714 3.096224569108951 1.0142996775008613 1.4110988113765228 0.8207175980646368 0.09176472079431001 0.11070752344262097 2.0210551503675993 0.03013530179051261 0.03426658683888914 3.8854604113751623e-07 6.410557511670714 0.39679913387566157 DFTNEAPPAPLPDAS(ph)ASPLSPHR ddPTM_PC-9_AZD4547_30min_R2 1 DFTNEAPPAPLPDASASPLSPHR 23 0 A0A494BZV2;Q6WCQ1-2;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 DFTNEAPPAPLPDAS(0.499)AS(0.499)PLS(0.003)PHR 115.31 1.8406e-08 3720900.0 22611.0 28943.0 57953.0 68653.0 64137.0 58053.0 49774.0 74575.0 56445.0 56105.0 True False 29800.827661983298 38298.25873878682 57184.505354182504 52826.11152827666 55232.68463520618 54422.93673280891 54203.78957498537 63051.14731301794 59428.56746524862 54140.78102703293 0.5504321713996609 0.7073828269980846 1.0562187000152403 0.9757175741868253 1.0201678584508793 1.0052115189405024 1.0011637908939839 1.164577719732857 1.0976673468300255 1.0 15.72442807936128 -5.1215846491591135 2.7037342439809726 1.0426957208467786 0.5570379537575386 0.902053852425352 0.05517248298559304 0.08761470592391916 1.1719354133678452 0.016103003659281138 0.06597813837681783 7.558147287023396e-06 5.1215846491591135 -0.48565776708924 DFTNEAPPAPLPDAS(ph)ASPLSPHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DFTNEAPPAPLPDASASPLSPHR 23 0 A0A494BZV2;Q6WCQ1-2;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 DFTNEAPPAPLPDAS(0.492)AS(0.473)PLS(0.035)PHR 104.84 1.4612999999999999e-06 3895900.0 24763.0 33556.0 45070.0 46906.0 58808.0 42339.0 42201.0 33240.0 33325.0 24845.0 True False 28954.886808456 36887.21791612178 46144.63972892684 44278.0088913038 47284.99455676029 40118.66830645025 38203.415771218366 32367.48522069122 33812.315080294014 29349.201827088204 0.9865647106536212 1.2568388787348987 1.572262169199337 1.508661433185446 1.6111168826784934 1.3669423973711692 1.3016849996907942 1.102840391073847 1.1520693230262407 1.0 14.84103364827627 -7.654522131956297 2.1668014195512506 1.0797229524414969 1.4023011482690373 0.37881154859945276 0.17047039474519768 0.36988653833498464 3.4614413351592956 0.11806574234085482 0.05487169424884871 2.2155311883876977e-08 7.654522131956297 0.32257819582754044 DFTNEAPPAPLPDAS(ph)ASPLSPHR ddPTM_PC-9_Lapatinib_30min_R1 2 DFTNEAPPAPLPDASASPLSPHR 23 0 A0A494BZV2;Q6WCQ1-2;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 DFTNEAPPAPLPDAS(0.481)AS(0.481)PLS(0.038)PHR;DFTNEAPPAPLPDAS(0.459)AS(0.289)PLS(0.252)PHR 140.42 1.4755999999999998e-07 14372300.0 42658.0 58455.0 84000.0 66526.0 70670.0 76308.0 63437.0 76408.0 78840.0 57255.0 True False 42049.68909748086 58319.65103896451 77093.84424937687 71418.5439642305 66513.32954256576 73044.48472263615 66721.45746037507 79958.19462111776 69960.2089779946 67151.45046250802 0.6261918217382071 0.8684793945221708 1.1480592558818947 1.0635443236494926 0.9904972876155738 1.0877573636837274 0.9935966684387104 1.190714334097072 1.041827220352519 1.0 16.03513094156207 -4.932398506201697 2.8710727673563365 1.0663693121056934 0.6106475542693495 0.8218610390394423 0.06386061379259053 0.11701477808196419 1.6818315204375214 0.01623980845057453 0.10664990771590424 1.168426757078413e-05 4.932398506201697 -0.45572175783634394 DFTNEAPPAPLPDAS(ph)ASPLSPHRR ddPTM_PC-9_AZD4547_30min_R2 1 DFTNEAPPAPLPDASASPLSPHRR 24 1 A0A494BZV2;Q6WCQ1-2;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 DFTNEAPPAPLPDAS(0.382)AS(0.309)PLS(0.309)PHRR 62.376999999999995 0.00099589 40632000.0 41132.0 38283.0 64624.0 73806.0 70648.0 58346.0 56023.0 73550.0 59911.0 69846.0 True False 54211.12040125145 50657.23108513196 63767.04353542848 56791.16699133297 60839.74467324706 54697.61539649058 61008.93846906829 62184.53751086123 63077.773149269386 67400.71279946795 0.8043107876698803 0.7515830171685046 0.9460885632641536 0.8425900058401351 0.9026572887182779 0.8115287379708892 0.9051675558770929 0.9226094936988872 0.9358621078228021 1.0 16.040476228327798 -1.5228787652237794 0.07613178495944294 1.1240489439902726 0.26403489541633673 0.5645462937198442 0.04808959434090292 163.30103939689485 0.9145134428156831 1.6507509392496493 14.863192688602512 0.029999998622355875 1.5228787652237794 -0.8600140485739358 DFTNEAPPAPLPDAS(ph)ASPLSPHRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DFTNEAPPAPLPDASASPLSPHRR 24 1 A0A494BZV2;Q6WCQ1-2;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 DFTNEAPPAPLPDAS(0.333)AS(0.333)PLS(0.333)PHRR;DFTNEAPPAPLPDAS(0.482)AS(0.184)PLS(0.334)PHRR 94.384 3.0107e-06 73545000.0 81675.0 96890.0 115404.0 99131.0 133449.0 92084.0 106008.0 79965.0 77483.0 71754.0 True False 95500.96434521845 106508.59887629755 118155.66903210712 93577.01145703837 107300.62642166186 87254.9529353826 95966.1548085428 77866.00347992094 78616.04229156545 84762.43219564862 1.1266897595008027 1.2565543026237664 1.3939627022426662 1.1039915801500828 1.2658983896779954 1.029405960579101 1.1321779274458965 0.918638145023855 0.927486862459349 1.0 16.37113736492656 -7.140280675784413 1.01883134702692 0.9447605991858367 1.243514642683741 0.606180512669789 0.09211303248793948 0.3490751724117201 0.7244692735389818 0.06192821771836844 0.039125037903257394 7.239679229494857e-08 7.140280675784413 0.29875404349790424 DFTNEAPPAPLPDASAS(ph)PLSPHR ddPTM_PC-9_AZD4547_30min_R2 1 DFTNEAPPAPLPDASASPLSPHR 23 0 A0A494BZV2;Q6WCQ1-2;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 DFTNEAPPAPLPDAS(0.208)AS(0.671)PLS(0.121)PHR 131.64 5.428100000000001e-07 29638000.0 19216.0 18922.0 26517.0 31172.0 25055.0 27576.0 24879.0 30486.0 27999.0 28356.0 True False 25326.288282370133 25038.16646012245 26165.367254099998 23985.777002599123 21576.545730780846 25851.668360703807 27093.182802990745 25775.089198587546 29478.9699789086 27363.265070894686 0.9255579777030625 0.915028465910475 0.9562224093619278 0.8765685286626093 0.7885223373336041 0.944758174644929 0.9901297499693771 0.94195956264019 1.0773191686932242 1.0 14.739952766956769 -6.998971231195343 24.999809154148153 0.9932195068617169 0.8933399519645828 0.5005810471427542 0.051465003576379724 33.58966256749295 816226.0322843257 0.01915805892403665 0.01676181849479196 1.0023716356028068e-07 6.998971231195343 -0.09987955489713407 DFTNEAPPAPLPDASAS(ph)PLSPHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DFTNEAPPAPLPDASASPLSPHR 23 0 A0A494BZV2;Q6WCQ1-2;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 DFTNEAPPAPLPDAS(0.174)AS(0.734)PLS(0.092)PHR;DFTNEAPPAPLPDAS(0.26)AS(0.557)PLS(0.183)PHR 133.56 6.7521e-07 13099300.0 53698.0 64157.0 83884.0 73918.0 103128.0 64938.0 70130.0 66299.0 66345.0 55358.0 True False 62788.01081615598 70526.0829611582 85884.11269184151 69776.61410538922 82920.8087105425 61532.53696318443 63486.7787027687 64558.72149959713 67315.17011259141 65393.9671863131 0.9601498963546204 1.0784799576423199 1.3133338805879478 1.0670191320032563 1.2680192421159264 0.9409512774759923 0.970835406298097 0.9872274810253324 1.0293789015859007 1.0 15.996869927935798 -6.782671346016329 24.999756987274363 0.9839526025818922 1.1399911129332063 0.38399139660400916 0.09604339742301127 258.95922278596703 304911.54940844513 0.03418217416759915 0.03017434167316817 1.649410116669047e-07 6.782671346016329 0.1560385103513141 DFTNEAPPAPLPDASAS(ph)PLSPHR ddPTM_PC-9_Lapatinib_30min_R1 1 DFTNEAPPAPLPDASASPLSPHR 23 0 A0A494BZV2;Q6WCQ1-2;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 DFTNEAPPAPLPDAS(0.395)AS(0.597)PLS(0.008)PHR 128.95 3.6155e-07 3905600.0 17159.0 24728.0 39876.0 26670.0 31613.0 34021.0 24765.0 31439.0 31667.0 21538.0 True False 16914.309513424792 24670.743835283785 36597.54920581135 28631.400768511914 29753.585493549348 32566.00113682447 26047.210523924354 32899.7707137122 28100.328991706687 25260.814602418977 0.6695868593170814 0.9766408654502106 1.44878737213434 1.133431412214639 1.1778553448034943 1.289190457607252 1.0311310594643321 1.3024033955960277 1.1124078710041203 1.0 14.624613542978986 -4.92472810496574 3.796758185526579 1.1951665850610256 0.6796764702543179 0.6074539268867143 0.1282425979866054 0.14088752028363472 3.763878522626668 0.030390031436878018 0.15905621297392145 1.1892465358352068e-05 4.92472810496574 -0.5154901148067077 DFTNEAPPAPLPDASAS(ph)PLSPHRR ddPTM_PC-9_AZD4547_30min_R2 1 DFTNEAPPAPLPDASASPLSPHRR 24 1 A0A494BZV2;Q6WCQ1-2;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 DFTNEAPPAPLPDAS(0.051)AS(0.474)PLS(0.474)PHRR 97.304 1.8669e-06 33492000.0 31624.0 22508.0 42928.0 64646.0 50225.0 42196.0 31238.0 53117.0 45684.0 46806.0 True False 41679.774179937194 29783.270832070382 42358.74667134309 49742.86347074373 43252.12569660617 39557.47744953066 34018.12148397545 44908.98815723197 48098.762974265526 45167.3361866376 0.9227857495892757 0.6593984358298626 0.937818128045253 1.101301685474641 0.9575974442655303 0.8757983266065054 0.7531575770465614 0.9942802022165288 1.06490147604709 1.0 15.462992210667117 -5.425291454526702 9.503275341421825 0.9561381179023818 0.7918315876517691 0.28005209052111246 0.10891780486804999 0.5353711007814919 48.71612882640004 0.02984928091875929 0.06221529164437312 3.755852648539194e-06 5.425291454526702 -0.1643065302506127 DFTNEAPPAPLPDASAS(ph)PLSPHRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DFTNEAPPAPLPDASASPLSPHRR 24 1 A0A494BZV2;Q6WCQ1-2;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 DFTNEAPPAPLPDAS(0.058)AS(0.471)PLS(0.471)PHRR 59.211999999999996 0.0018457999999999999 19470000.0 26132.0 23614.0 37903.0 32737.0 34549.0 28653.0 29781.0 34085.0 30658.0 28351.0 True False 30555.63146947349 25958.241860510785 38806.751267927975 30902.852024786 27779.371462071664 27150.386239276304 26959.928084231495 33190.30486604273 31106.315250762316 33490.8118736075 0.9123586368938675 0.7750854759351842 1.1587282928339433 0.9227262731465479 0.829462467703366 0.8106816383472693 0.8049947605324349 0.9910271805682447 0.9288014685387699 1.0 15.031477729372229 -11.549323224896035 6.037127652678986 1.1404211760566123 0.9027736668401727 0.06796349424711057 0.10685941236489716 0.10734259188817213 0.00047019369134689243 0.054991241357602846 0.025982583484687433 2.8227783321813895e-12 11.549323224896035 -0.23764750921643962 DFTNEAPPAPLPDASAS(ph)PLSPHRR ddPTM_PC-9_Lapatinib_30min_R1 1 DFTNEAPPAPLPDASASPLSPHRR 24 1 A0A494BZV2;Q6WCQ1-2;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 DFTNEAPPAPLPDAS(0.048)AS(0.476)PLS(0.476)PHRR 65.33 0.0004838 25790000.0 12405.0 12628.0 20479.0 17913.0 19595.0 15953.0 12321.0 15518.0 21455.0 13909.0 True False 12228.102425201612 12598.760641862013 18795.29567122607 19230.381776016267 18442.460625252254 15270.727378259333 12958.921092883997 16239.022931244184 19038.511968834035 16313.15211742247 0.7495855085015716 0.772306942960859 1.1521559742676994 1.178826853179294 1.130527104296151 0.936099122250578 0.7943848619571107 0.9954558637322387 1.167065189596367 1.0 13.993747954045267 -5.243015514214318 22.644555868144522 1.0392442209305237 0.7609458972920128 0.49432821239840063 0.11454860413277647 230.481804115685 283277.4885517023 0.033031936876334204 0.08687669021483074 5.714582222202475e-06 5.243015514214318 -0.2782983236385109 DFTNEAPPAPLPDASASPLS(ph)PHR ddPTM_PC-9_AZD4547_30min_R2 1 DFTNEAPPAPLPDASASPLSPHR 23 0 A0A494BZV2;Q6WCQ1-2;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 DFTNEAPPAPLPDAS(0.387)AS(0.198)PLS(0.415)PHR 88.927 1.366e-05 10900000.0 47137.0 53466.0 62423.0 68881.0 60150.0 68899.0 57907.0 74822.0 64495.0 64431.0 True False 62125.585489492114 70747.8389153846 61595.23023353639 53001.54965084149 51799.21076457663 64590.734638240945 63060.61081927671 63259.979138513336 67904.07403084796 62175.29030127009 0.9992005696871357 1.1378770983227622 0.9906705692096809 0.8524535936064426 0.8331157042224296 1.0388489434511174 1.0142391054986122 1.017445657784425 1.0921392357288413 1.0 15.924053718062801 -10.516116169703977 11.119499707421397 1.0000000028303822 0.9944888649606805 0.0 0.08901279578734232 0.0 0.0 0.09504196295351323 0.023051061889610338 3.0470798153117976e-11 10.516116169703977 -0.005511137869701699 DFTNEAPPAPLPDASASPLS(ph)PHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DFTNEAPPAPLPDASASPLSPHR 23 0 A0A494BZV2;Q6WCQ1-2;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 DFTNEAPPAPLPDAS(0.112)AS(0.16)PLS(0.728)PHR;DFTNEAPPAPLPDAS(0.02)AS(0.038)PLS(0.942)PHR;DFTNEAPPAPLPDAS(0.218)AS(0.15)PLS(0.631)PHR;DFTNEAPPAPLPDAS(0.062)AS(0.105)PLS(0.832)PHR 139.59 2.017e-11 28749100.0 70999.0 87460.0 93610.0 83858.0 117402.0 80857.0 94009.0 76891.0 81893.0 68445.0 True False 83017.72840583 96142.45079699646 95842.01741790211 79159.70813130404 94397.92087730854 76616.71657938664 85103.78695377981 74872.69272274862 83090.53019866507 80853.5366896782 1.026766815710958 1.1890939436081593 1.1853781707255526 0.9790506559425446 1.1675175229454053 0.9475988276610238 1.0525672770557257 0.9260286660077158 1.0276672313985795 1.0 16.30302326089297 -6.6343223342847 1.1662344315137947 0.9862567540078764 1.1223840766162763 0.3156973551441392 0.07667731907991042 0.5225247707541768 1.505984078237589 0.03589875379385467 0.03662181425910511 2.321013495782953e-07 6.6343223342847 0.13612732260839988 DFTNEAPPAPLPDASASPLS(ph)PHR ddPTM_PC-9_Lapatinib_30min_R1 1 DFTNEAPPAPLPDASASPLSPHR 23 0 A0A494BZV2;Q6WCQ1-2;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 DFTNEAPPAPLPDAS(0.02)AS(0.051)PLS(0.93)PHR 126.8 2.1666999999999997e-07 10078000.0 27143.0 26436.0 35422.0 36694.0 36128.0 36669.0 34087.0 36162.0 35251.0 33709.0 True False 26755.935842583407 26374.78906622299 32509.739892874142 39392.599167595625 34003.02207038087 35100.75234961399 35851.85807102807 37842.218535871434 31280.661170513566 39535.555735580856 0.6767562854441892 0.6671156779133484 0.8222912082051832 0.9963841012140732 0.860061821257748 0.8878274681244541 0.906825701674972 0.9571692576921217 0.7912032748375376 1.0 15.27086308373238 -5.406244892530339 3.4755401601675713 0.9090525001908779 0.6714618015731235 0.7182551357901755 0.059918660178904924 0.11836609346385492 2.5945003647888556 0.015364288742216129 0.03537252537051113 3.924235908732415e-06 5.406244892530339 -0.2375906986177544 DFTNEAPPAPLPDASASPLS(ph)PHRR ddPTM_PC-9_AZD4547_30min_R2 4 DFTNEAPPAPLPDASASPLSPHRR 24 1 A0A494BZV2;Q6WCQ1-2;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 DFTNEAPPAPLPDAS(0.162)AS(0.162)PLS(0.676)PHRR;DFTNEAPPAPLPDAS(0.012)AS(0.186)PLS(0.803)PHRR;DFTNEAPPAPLPDAS(0.197)AS(0.009)PLS(0.794)PHRR;DFTNEAPPAPLPDAS(0.138)AS(0.096)PLS(0.766)PHRR 121.47 3.4556e-09 22427500.0 26896.699999999997 22783.199999999997 38677.6 47513.2 41535.1 36945.3 31757.0 45306.100000000006 31700.500000000004 35422.8 True False 35449.29111388554 30147.423850241077 38164.7097525051 36559.7658116224 35768.66831301358 34635.10455057697 34583.3114785392 38305.08327560608 33376.123712146604 34182.65855386117 1.0370548287819263 0.8819508231853346 1.1164933146545482 1.0695413217791603 1.0463980809641635 1.0132361266167431 1.0117209410159462 1.1205998859114266 0.976405145888705 1.0 15.060976986432296 -5.26476083994493 24.999466899386253 1.047310027168216 0.9595028292617844 0.260967544608648 0.05689884112562416 324.28877407657274 2440826.7238659533 0.014022608112001933 0.03128874201754507 5.4354957443658036e-06 5.26476083994493 -0.08780719790643166 DFTNEAPPAPLPDASASPLS(ph)PHRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DFTNEAPPAPLPDASASPLSPHRR 24 1 A0A494BZV2;Q6WCQ1-2;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 DFTNEAPPAPLPDAS(0.048)AS(0.048)PLS(0.904)PHRR;DFTNEAPPAPLPDAS(0.009)AS(0.237)PLS(0.754)PHRR;DFTNEAPPAPLPDAS(0.004)AS(0.047)PLS(0.949)PHRR;DFTNEAPPAPLPDAS(0.26)AS(0.167)PLS(0.573)PHRR 103.92 8.2084e-07 42669600.0 55443.0 62732.0 80266.0 84199.0 88256.0 80470.0 82795.0 77824.0 81664.0 61487.0 True False 64828.40485083493 68959.61837865526 82179.8458505001 79481.60300684096 70962.87035099692 76250.01154066117 74952.05821610922 75781.20246134387 82858.18150689051 72634.10636917585 0.8925339360731301 0.949410983707236 1.1314222747204505 1.0942738470941116 0.9769910293976143 1.0497824693141655 1.0319127192830317 1.0433280761543666 1.1407613537055026 1.0 16.148359524676703 -5.067340294248692 5.418233349034105 1.0569513602280507 0.9044901220704604 0.5618450952273795 0.04968859174360976 0.1365752872717783 7.653319750117099 0.012894567595624623 0.03743122606850676 8.563665707117046e-06 5.067340294248692 -0.15246123815759027 DFTNEAPPAPLPDASASPLS(ph)PHRR ddPTM_PC-9_Lapatinib_30min_R1 5 DFTNEAPPAPLPDASASPLSPHRR 24 1 A0A494BZV2;Q6WCQ1-2;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 DFTNEAPPAPLPDAS(0.011)AS(0.055)PLS(0.934)PHRR;DFTNEAPPAPLPDAS(0.29)AS(0.061)PLS(0.649)PHRR;DFTNEAPPAPLPDAS(0.046)AS(0.046)PLS(0.909)PHRR;DFTNEAPPAPLPDAS(0.005)AS(0.024)PLS(0.971)PHRR;DFTNEAPPAPLPDAS(0.012)AS(0.098)PLS(0.89)PHRR 187.01 7.8334e-21 137406300.0 238636.0 315828.0 368799.0 348329.0 430940.0 395072.0 353252.0 371412.0 389316.0 316984.0 True False 235233.00687951714 315096.71967041475 338477.7698253088 373946.27665148006 405592.9564606378 378175.69151781296 371541.66008468956 388669.157426168 345467.1324007727 371774.2620453698 0.6327307479150084 0.8475485041295345 0.9104389528288604 1.0058422941764733 1.0909656688690863 1.017218592371685 0.999374346251404 1.0454439618489146 0.9292389701754377 1.0 18.50406737028645 -4.665893065052529 1.0713422462723134 1.017379560246174 0.37494901854092777 0.8844498671112413 0.04227444754194725 0.6723347127835532 0.5385268150742056 0.013760518949072709 0.5225301057036824 2.158275769103051e-05 4.665893065052529 -0.6424305417052462 DFTPVCTTELGR ddPTM_PC-9_Lapatinib_30min_R1 2 DFTPVCTTELGR 12 0 P30041 P30041 PRDX6 Peroxiredoxin-6 0 ; 163.84 0.00093596 24670000.0 26900.0 23126.0 19542.2 23579.0 20660.2 22355.2 21708.1 19845.0 22073.2 20340.3 False True 26516.401067144157 23072.453167857217 17935.5157510735 25313.078317238178 19445.00765551602 21399.120208516466 22832.039199450937 20767.07114773431 19587.08377489942 23856.09375325388 1.1115147912062266 0.9671513453333164 0.7518211462690603 1.0610738949575753 0.8150960445007387 0.8970085559626755 0.957073669964796 0.8705143164899644 0.8210515928337101 1.0 14.542070212013853 -4.861611880573321 3.8637326116290716 0.8952468966097037 1.1161136640750553 0.357057039868264 0.0872349810067293 0.2323742014684217 5.789192192843859 0.020595917110162478 0.12177792434067429 1.3752704749650734e-05 4.861611880573321 0.2208667674653516 DFTSEPR ddPTM_PC-9_Lapatinib_30min_R1 1 DFTSEPR 7 0 Q2VIR3;P41091;Q2VIR3-2 Q2VIR3 EIF2S3L;EIF2S3 Putative eukaryotic translation initiation factor 2 subunit 3-like protein;Eukaryotic translation initiation factor 2 subunit 3 0 88.029 0.029306 0.0 42401.0 43981.0 71347.0 52094.0 52467.0 61261.0 49003.0 54261.0 71483.0 47921.0 False True 41796.3539646089 43879.16469668459 65481.125067384426 55925.16654048968 49380.99421409083 58641.00983636588 51540.135566479505 56782.16414951932 63431.83179063909 56204.080999281214 0.743653365049122 0.7807113632415011 1.165059972570708 0.9950374696315183 0.8786015772541919 1.043358574568915 0.9170176729184246 1.0102854301673485 1.1285983270761122 1.0 15.778387268423906 -5.139513819838127 7.110234091596886 1.0089092200406669 0.753921608338297 0.6121731299231832 0.08115343028987972 0.1627412207393151 8.681536609162338 0.020878765621643005 0.05635207098137233 7.252473993703554e-06 5.139513819838127 -0.25498761170236983 DFTVSAMHGDMDQK ddPTM_PC-9_AZD4547_30min_R2 1 DFTVSAMHGDMDQK 14 0 P60842;P60842-2;J3KT12;J3KSZ0;J3QL52 P60842 EIF4A1 Eukaryotic initiation factor 4A-I 0 67.095 0.020194 11291000.0 11160.0 8967.4 28663.0 32020.0 26848.0 25320.0 16361.0 24812.0 21645.0 21861.0 False True 14708.647857579655 11865.93668293531 28282.909891928488 24638.283704068515 23120.6186302137 23736.736397339006 17817.097304543262 20977.875523038565 22789.110510856714 21095.653043970546 0.6972359578971938 0.5624825483336612 1.3406984762679421 1.1679317844635535 1.0959897084969323 1.125195619583975 0.8445861935350542 0.9944169767730587 1.0802751857625088 1.0 14.364658128339943 -5.245167457381145 24.99825276607005 1.077692935839583 0.6298591786318728 0.6757550466368643 0.12502081921518765 497.81776964027154 764785.4790399645 0.03405778407788647 0.0895174091635918 5.686336320425837e-06 5.245167457381145 -0.44783375720771024 DFVDDDDDDDLER ddPTM_PC-9_Lapatinib_30min_R1 1 DFVDDDDDDDLER 13 0 G3V4K3;Q9H9C1-2;Q9H9C1 G3V4K3 VIPAS39 Spermatogenesis-defective protein 39 homolog 0 214.04 1.1389e-13 5154000.0 14945.0 14360.0 17874.0 16228.0 14380.0 19278.0 12597.0 17143.0 17375.0 13076.0 False True 14731.881559422667 14326.750302275765 16404.468715635263 17421.46125502105 13534.196672167765 18453.52487921292 13249.21102240562 17939.526363598357 15418.044533138709 15336.169177325217 0.9605972253621198 0.9341805073106592 1.0696588258748179 1.1359721618602756 0.8825017848771715 1.203268212931347 0.8639192010215172 1.1697527691675602 1.005338709743405 1.0 13.90465053650526 -5.257053440874099 24.43215905906937 1.044523183538173 0.9473888558365717 0.11077218540284961 0.10611905720210678 533.3747020073306 2971163.66231147 0.025076472113050762 0.06149601716497801 5.532820224787259e-06 5.257053440874099 -0.09713432770160124 DFVT(ph)ISPVQPEER ddPTM_PC-9_Lapatinib_30min_R1 1 DFVTISPVQPEER 13 0 Q9H611-2;Q9H611-4;Q9H611;Q9H611-3 Q9H611-2 PIF1 ATP-dependent DNA helicase PIF1 1 DFVT(0.752)IS(0.248)PVQPEER 97.2 0.0075092 1435000.0 10411.0 9624.1 9697.3 8161.8 8835.6 10892.0 8738.5 8503.0 10007.0 9958.1 True False 10262.537230856431 9601.81598775294 8900.025426660504 8762.045998966641 8315.907379457965 10426.17455049212 9190.93677219112 8898.08042172763 8879.906281618369 11679.344316665814 0.8786912135309108 0.8221194381650047 0.7620312566657216 0.750217286296086 0.7120183422961167 0.8927020445500963 0.7869394482253711 0.7618647229220338 0.7603086304209052 1.0 13.511671662530464 -11.161550096688323 2.7239875377695104 1.0217320579367548 0.7902520487921382 0.5685416289973969 0.05437476364400187 23448882.175236695 21139002.725443047 3580906.8185777967 0.014567220896720382 6.893660689069805e-12 11.161550096688323 -0.23148000914461664 DFVTIS(ph)PVQPEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DFVTISPVQPEER 13 0 Q9H611-2;Q9H611-4;Q9H611;Q9H611-3 Q9H611-2 PIF1 ATP-dependent DNA helicase PIF1 1 DFVT(0.004)IS(0.996)PVQPEER 132.65 0.00038417 0.0 8585.3 6941.3 9058.3 10558.0 7350.6 7974.6 8380.2 8874.4 10682.0 7786.5 True False 10038.621722595704 7630.386390546439 9274.284225794056 9966.469489497833 5910.302696723609 7556.397937519029 7586.366788606057 8641.456403204034 10838.204041641427 9198.130812099918 1.0913762728173142 0.8295583685881973 1.0082792270788277 1.0835320450528039 0.6425547556845733 0.8215145111416301 0.8247726569213796 0.9394796159928936 1.1783050559994246 1.0 13.167124999951783 -8.09576218437571 5.91238577152006 1.0856880502263249 0.8948458348327356 0.23326318574130767 0.13466501848500376 0.34206743123664135 17.02909770810876 0.09579202751237692 0.03541278144198638 8.021171750644655e-09 8.09576218437571 -0.19084221539358925 DFVTIS(ph)PVQPEER ddPTM_PC-9_Lapatinib_30min_R1 1 DFVTISPVQPEER 13 0 Q9H611-2;Q9H611-4;Q9H611;Q9H611-3 Q9H611-2 PIF1 ATP-dependent DNA helicase PIF1 1 DFVT(0.237)IS(0.763)PVQPEER 109.99 0.00072574 1351100.0 11616.0 10203.0 11859.0 11312.0 13271.0 11496.0 13039.0 10730.0 13323.0 9274.1 True False 11450.35370988649 10179.375580370448 10883.998797063821 12143.92221572579 12490.425871789877 11004.342878484882 13714.095619683007 11228.554971790832 11822.42344259034 10877.115828038526 1.0527012758630645 0.9358524577011973 1.000632793576359 1.1164652843377607 1.148321491584436 1.01169676341208 1.2608209599397153 1.032309956913981 1.0869079294085517 1.0 13.409008442369396 -5.725356534105987 6.844729937304868 1.1009637406736124 0.9892900143079271 0.25077510465945196 0.07621188386847365 0.22933891788099608 30.766449717227953 0.019891554951105762 0.03404097414687834 1.882103342125842e-06 5.725356534105987 -0.11167372636568529 DGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVSS(ph)PVQEK ddPTM_PC-9_AZD4547_30min_R2 1 DGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEK 41 1 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 DGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVS(0.322)S(0.677)PVQEK 57.925 2.0924e-05 5301100.0 29329.0 29032.0 33225.0 33296.0 40776.0 43175.0 39343.0 46080.0 43434.0 39688.0 True False 38655.01191890264 38416.02624829696 32784.41479117065 25620.12161807201 35114.95624499378 40475.26042476747 42844.450782509935 38959.39481305888 45729.8325677316 38298.53520008703 1.009307842113366 1.0030677687174225 0.8560226812824985 0.6689582639185059 0.9168746549062269 1.0568357304870366 1.1186968524689835 1.0172554801252647 1.1940360728894843 1.0 15.225001594154444 -6.752350294933432 4.20547987936489 1.0835580924314239 0.8802610472947883 0.46212076555067405 0.10110974879430897 0.2004960082044691 8.162160048024525 0.038276352056172865 0.03604802903411136 1.7686817925866015e-07 6.752350294933432 -0.2032970451366356 DGAS(ph)SSPESASRR ddPTM_PC-9_Lapatinib_30min_R1 1 DGASSSPESASRR 13 1 G5E9M9;A0A075B6E4;A0A0A6YYI5;G5E9M7;Q14135-5;Q14135-6;Q14135-2;Q14135;Q14135-4 G5E9M9 VGLL4 Transcription cofactor vestigial-like protein 4 1 DGAS(0.41)S(0.343)S(0.243)PES(0.002)AS(0.002)RR 53.3 0.040142000000000004 5025700.0 27231.0 18340.0 24781.0 17065.0 22288.0 21003.0 13326.0 13039.0 19553.0 15721.0 True False 26842.680946446202 18297.53485680625 22743.601837426304 18320.017027171198 20977.06365989396 20104.750650384318 14015.95507538123 13644.839541209756 17350.73523778195 18438.353903084248 1.4558067974796889 0.9923627105207888 1.2334941588045938 0.9935820260021555 1.1376863558511616 1.0903766548824798 0.7601521886960165 0.7400248207041593 0.9410132449448014 1.0 14.170422243458745 -7.152964549310997 4.821690609676217 0.8397149580302141 1.1443907780337945 0.4980701525291219 0.14279317624504886 0.1846878942193044 6.688014366715635 0.05349315639036092 0.04101399031490562 7.031297127738946e-08 7.152964549310997 0.3046758200035804 DGASS(ph)SPESASR ddPTM_PC-9_AZD4547_30min_R2 1 DGASSSPESASR 12 0 G5E9M9;A0A075B6E4;A0A0A6YYI5;G5E9M7;Q14135-5;Q14135-6;Q14135-2;Q14135;Q14135-4 G5E9M9 VGLL4 Transcription cofactor vestigial-like protein 4 1 DGAS(0.023)S(0.574)S(0.403)PESASR 91.20200000000001 0.0065327 28873000.0 8624.5 6469.0 10519.0 13159.0 11183.0 9391.3 8075.9 10742.0 8932.5 10700.0 True False 11366.91159925589 8559.97774181017 10379.511187007502 10125.395854523356 9630.433482631097 8804.060526395335 8794.639454908678 9082.070726603271 9404.653713939826 10325.396256826527 1.100869285451469 0.8290217178009832 1.005240954326106 0.980630244367528 0.9326938398382568 0.8526607897081551 0.8517483722810343 0.8795856837551156 0.9108273890914393 1.0 13.333909528437637 -6.531218321775362 5.188893512478707 0.8884680547772467 0.9689818723395047 0.19658950885857507 0.07356004045677962 0.27659240601107954 22.583082682139526 0.023030182593527668 0.024033421661639524 2.9429418318780394e-07 6.531218321775362 0.08051381756225806 DGASS(ph)SPESASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DGASSSPESASR 12 0 G5E9M9;A0A075B6E4;A0A0A6YYI5;G5E9M7;Q14135-5;Q14135-6;Q14135-2;Q14135;Q14135-4 G5E9M9 VGLL4 Transcription cofactor vestigial-like protein 4 1 DGAS(0.06)S(0.578)S(0.361)PESASR;DGAS(0.139)S(0.52)S(0.341)PESASR 134.18 5.6618999999999994e-05 53865000.0 16956.3 19246.6 21320.9 19864.4 23610.0 20852.0 23272.0 18595.6 18920.1 14664.5 True False 19826.66668780934 21157.27525165185 21829.27111596353 18751.462069253725 18983.78998580312 19758.484412151927 21067.50768531063 18107.485203666845 19196.770669187412 17323.05776588187 1.1445246535434628 1.221336067661308 1.2601280565465032 1.082456822731673 1.0958683069909343 1.1405887274166275 1.216154097621468 1.0452822733945921 1.1081629426299011 1.0 14.08040598826949 -14.506871621708662 0.05647761088358025 0.3832818754843682 1.4189231660451596 0.4474479985015789 0.058046805916528686 423.593222560419 1.7537434069794975 36.45031006280893 6.733633596433634 3.1126363024567553e-15 14.506871621708662 1.0356412905607915 DGASS(ph)SPESASRR ddPTM_PC-9_Lapatinib_30min_R1 1 DGASSSPESASRR 13 1 G5E9M9;A0A075B6E4;A0A0A6YYI5;G5E9M7;Q14135-5;Q14135-6;Q14135-2;Q14135;Q14135-4 G5E9M9 VGLL4 Transcription cofactor vestigial-like protein 4 1 DGAS(0.019)S(0.422)S(0.422)PES(0.069)AS(0.069)RR 82.65100000000001 0.015093 2138200.0 17348.0 9339.7 13273.0 12400.0 12259.0 11241.0 7828.4 9277.5 12254.0 9498.6 True False 17100.614338766427 9318.074498479453 12181.745175261665 13311.937365187392 11537.949722121319 10760.248634050851 8233.71624734462 9708.566519178888 10873.825479659392 11140.420353911077 1.5350062022357083 0.8364203685732692 1.093472668738663 1.1949223586086641 1.035683516023763 0.9658745623789 0.739084880621583 0.8714721896261746 0.9760695857263508 1.0 13.44351604948606 -6.701246791388043 2.458822541150822 0.8847638751231114 1.1348529936119254 0.3163961881908356 0.17366368668949275 0.3626476889714952 4.48478380665071 0.06321003837598131 0.06067059347768632 1.9895424439467472e-07 6.701246791388043 0.250089118488814 DGASSS(ph)PESASR ddPTM_PC-9_AZD4547_30min_R2 1 DGASSSPESASR 12 0 G5E9M9;A0A075B6E4;A0A0A6YYI5;G5E9M7;Q14135-5;Q14135-6;Q14135-2;Q14135;Q14135-4 G5E9M9 VGLL4 Transcription cofactor vestigial-like protein 4 1 DGAS(0.001)S(0.141)S(0.858)PESASR 174.46 0.0011099 32942000.0 12092.0 9271.1 12748.0 18742.0 16568.0 15609.0 11658.0 13308.0 11964.0 13310.0 True False 15937.004470775371 12267.80176875813 12578.953190604767 14421.321461013502 14267.819184497188 14632.966762482803 12695.53941546148 11251.554387417267 12596.392615009912 12844.020951248702 1.240811154954241 0.9551371657927301 0.9793625561924855 1.122804261667874 1.1108529983447328 1.1392823803405723 0.9884396376842732 0.8760149512465086 0.9807203416143045 1.0 13.64880930306102 -7.460585266144202 5.845544426079355 0.9433960950824892 1.0817206356698132 0.37866263806868994 0.0817642137100601 0.23601473508192225 16.3165842001451 0.03587779407239454 0.023561141167683857 3.462698938819553e-08 7.460585266144202 0.13832454058732402 DGASSS(ph)PESASR ddPTM_PC-9_Lapatinib_30min_R1 1 DGASSSPESASR 12 0 G5E9M9;A0A075B6E4;A0A0A6YYI5;G5E9M7;Q14135-5;Q14135-6;Q14135-2;Q14135;Q14135-4 G5E9M9 VGLL4 Transcription cofactor vestigial-like protein 4 1 DGASS(0.07)S(0.93)PESASR 205.31 8.311899999999999e-08 28525000.0 16879.0 16108.0 19114.0 14265.0 16617.0 17867.0 17539.0 17422.0 18979.0 13581.0 True False 16638.302364770505 16070.702915672566 17542.52070217368 15314.095686645003 15639.620730278973 17102.870060011268 18447.083601013903 18231.48972213793 16841.385162269904 15928.457754455016 1.0445645536597512 1.0089302532241557 1.101332029289981 0.9614299088285442 0.9818666044994057 1.0737304467049098 1.1581211367343116 1.144585998417755 1.0573142373158853 1.0 13.95931896670699 -6.965137837419685 7.478776440609489 1.104037825754428 1.0208041155293717 0.26370781568333157 0.054600653471881505 0.2358609927052202 40.50942372539375 0.019336586385297585 0.016924370967289354 1.0835829492960654e-07 6.965137837419685 -0.08323371022505643 DGASSS(ph)PESASRR ddPTM_PC-9_Lapatinib_30min_R1 1 DGASSSPESASRR 13 1 G5E9M9;A0A075B6E4;A0A0A6YYI5;G5E9M7;Q14135-5;Q14135-6;Q14135-2;Q14135;Q14135-4 G5E9M9 VGLL4 Transcription cofactor vestigial-like protein 4 1 DGAS(0.023)S(0.076)S(0.852)PES(0.001)AS(0.049)RR 133.04 7.1658e-05 2362900.0 25080.0 13021.0 19246.0 13438.0 16373.0 14819.0 11899.0 10032.0 16852.0 11654.0 True False 24722.354600891285 12990.850674507856 17663.668171708432 14426.275347853882 15409.972330556522 14185.225914776234 12515.07199774585 10498.123343616562 14953.950300572864 13668.378372021109 1.8087262386222378 0.9504310109749274 1.292301668196836 1.0554489314829163 1.127417745626681 1.0378133768825937 0.9156222967432587 0.7680591697041403 1.0940544586608236 1.0 13.738554470085315 -3.123736672817203 1.7153263839683026 1.020174341843898 199.99603425135632 0.7296099849883346 0.13974241107291688 190.45783891946672 2.8562935725621066 0.03992923026045488 147325.52771538735 0.0007520787661583203 3.123736672817203 198.97585990951242 DGASSSPESAS(ph)RR ddPTM_PC-9_AZD4547_30min_R2 1 DGASSSPESASRR 13 1 G5E9M9;A0A075B6E4;A0A0A6YYI5;G5E9M7;Q14135-5;Q14135-6;Q14135-2;Q14135;Q14135-4 G5E9M9 VGLL4 Transcription cofactor vestigial-like protein 4 1 DGAS(0.01)S(0.019)S(0.209)PES(0.063)AS(0.699)RR 83.85600000000001 0.016812 0.0 14123.0 11846.0 22052.0 32905.0 24482.0 20470.0 13335.0 20473.0 13992.0 17617.0 True False 18613.82022335102 15674.98783884422 21759.576071479165 25319.260627182222 21083.096890080877 19190.007664041445 14521.789166682009 17309.36827273775 14731.58855476586 17000.234192197462 1.0949155178046983 0.9220454060590833 1.279957430319759 1.4893477549152185 1.2401650854761348 1.128808429759692 0.8542111245353916 1.0181841071743687 0.8665520950015597 1.0 14.053267000359172 -7.089801253646373 4.472131558244766 0.9377276038289434 1.2079288508771873 0.44658664740609266 0.1424423467131234 0.24520245636154098 8.523261972472 0.06247633052686502 0.048440574088770345 8.132025772378833e-08 7.089801253646373 0.2702012470482439 DGDGVPGGGPLS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 2 DGDGVPGGGPLSPAR 15 0 M0QZR4;Q92888-2;Q92888;Q92888-3 M0QZR4 ARHGEF1 Rho guanine nucleotide exchange factor 1 1 DGDGVPGGGPLS(1)PAR;DGDGVPGGGPLS(1)PAR 130.02 1.3517000000000001e-05 74528000.0 46735.0 53884.0 53261.0 61983.0 55914.0 61136.0 49684.0 68399.0 53703.0 52751.0 True False 61595.75785161152 71300.94924094903 52554.7243398808 47693.776977803864 48151.306245894244 57313.15625543906 54105.779749338486 57829.50620265653 56541.63094315256 50904.20354615477 1.2100328373817444 1.4006888286995898 1.032424056929395 0.9369319949100074 0.9459200398300215 1.1259022293409089 1.0628941419401807 1.1360457913897541 1.1107458128067231 1.0 15.635497175040824 -5.27290151779752 24.947069300189003 1.0450102184441503 1.305360831552299 0.6407812490212141 0.07831408444159338 405.55545989585704 882682.5703686631 0.021867872715306956 0.04614426624843216 5.334558501694619e-06 5.27290151779752 0.2603506131081488 DGDGVPGGGPLS(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DGDGVPGGGPLSPAR 15 0 M0QZR4;Q92888-2;Q92888;Q92888-3 M0QZR4 ARHGEF1 Rho guanine nucleotide exchange factor 1 1 DGDGVPGGGPLS(1)PAR;DGDGVPGGGPLS(1)PAR;DGDGVPGGGPLS(1)PAR 133.23 4.4576e-06 66680300.0 71438.0 87810.0 90227.0 72207.0 98314.0 74993.0 95859.0 85322.0 77121.0 67609.0 True False 83531.04243518483 96527.19648392686 92378.35386780296 68161.47588825242 79050.07745295405 71060.23506236859 86778.54156093983 83082.3879061315 78248.74872640216 79865.97650745042 1.0458902036637905 1.2086147406577088 1.156667180538202 0.8534482250009661 0.9897841472655097 0.8897435199548286 1.0865520632912384 1.0402726109331553 0.9797507292620732 1.0 16.285293414894348 -5.731508236957296 24.996749328489145 0.9802085703047045 1.144213279130281 0.49953782832443283 0.07322735007461759 170.33305215298023 142251.0539793028 0.020168488178197073 0.034926941340899985 1.855631614643052e-06 5.731508236957296 0.1640047088255765 DGDGVPGGGPLS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 2 DGDGVPGGGPLSPAR 15 0 M0QZR4;Q92888-2;Q92888;Q92888-3 M0QZR4 ARHGEF1 Rho guanine nucleotide exchange factor 1 1 DGDGVPGGGPLS(1)PAR;DGDGVPGGGPLS(1)PAR 127.05 2.1878000000000003e-05 65712000.0 31931.0 38251.0 41195.0 36283.0 40781.0 46246.0 36602.0 43191.0 43417.0 29474.0 True False 31475.658084571754 38162.43215963443 37808.10611729857 38951.37285653985 38382.341758530834 44268.16638469139 38497.07246503855 45197.81153649747 38526.92025872135 34568.541628363666 0.9105289549949025 1.103964192933206 1.0937142365958772 1.1267866974341796 1.1103257456206346 1.2805910894536878 1.113644679573393 1.3074838974234435 1.1145081176091565 1.0 15.077172120265521 -3.77260549703143 0.7842987344449662 1.169018186841169 4.570486882116003e-17 0.38761851472176223 0.08580533794353566 10.085864714033349 1.451099377425122 0.0297662442485523 14.91071106925558 0.00016880857468224905 3.77260549703143 -1.169018186841169 DGDKPEETQGK ddPTM_PC-9_Lapatinib_30min_R1 1 DGDKPEETQGK 11 1 F5H6X6;Q14697;Q14697-2;E9PKU7 F5H6X6 GANAB Neutral alpha-glucosidase AB 0 75.819 0.027612 3893500.0 16122.0 28274.0 19590.0 17924.0 29567.0 17386.0 28421.0 35535.0 30674.0 24879.0 False True 15892.097323587288 28208.533290149382 17979.385819586827 19242.19075271118 27827.927190958566 16642.441308745503 29892.50031497897 37186.08582689539 27219.171108460276 29179.302000816293 0.5446359656972846 0.9667309138978117 0.6161691537064132 0.659446574567578 0.9536872126063906 0.5703509051820338 1.0244419251064583 1.2743994296318364 0.9328246134091494 1.0 14.832657752455527 -7.397493413026989 5.976477777480762 1.0906433276787968 0.7341720946803894 0.5212022220289281 0.1587782160953145 0.17842251086911332 7.932536199238101 0.06387104756396084 0.04253702520645413 4.004115413527109e-08 7.397493413026989 -0.35647123299840744 DGDKS(ph)PMSSLQISNEK ddPTM_PC-9_AZD4547_30min_R2 1 DGDKSPMSSLQISNEK 16 1 Q9UER7-3;Q9UER7;Q9UER7-2;Q9UER7-5;Q9UER7-4 Q9UER7-3 DAXX Death domain-associated protein 6 1 DGDKS(0.996)PMS(0.003)S(0.001)LQISNEK 64.565 0.045656 30981000.0 24235.0 26028.0 27594.0 24189.0 23640.0 30511.0 32969.0 30341.0 28994.0 29741.0 True False 31941.225880684848 34441.04199471866 27228.085530400687 18612.599766324598 20357.99405610294 28603.142346730263 35903.17713058411 25652.495616819007 30526.563647575844 28699.77664245586 1.1129433611491555 1.2000456457828208 0.9487211649627235 0.6485276871036967 0.709343292448735 0.9966329251642103 1.2509915173859643 0.8938221344507267 1.0636516105291773 1.0 14.808751888642915 -5.292548670630355 8.319801365538542 0.9295648203140687 1.1564644441847083 0.2215384245387353 0.1623722815130835 0.4249341533123036 106.5665289276488 0.0474345555487393 0.10110599916675894 5.098604551949107e-06 5.292548670630355 0.22689962387063956 DGDKS(ph)PMSSLQISNEK ddPTM_PC-9_Lapatinib_30min_R1 4 DGDKSPMSSLQISNEK 16 1 Q9UER7-3;Q9UER7;Q9UER7-2;Q9UER7-5;Q9UER7-4 Q9UER7-3 DAXX Death domain-associated protein 6 1 DGDKS(0.982)PMS(0.017)S(0.001)LQISNEK;DGDKS(0.917)PMS(0.041)S(0.041)LQISNEK;DGDKS(0.882)PMS(0.059)S(0.059)LQISNEK;DGDKS(0.929)PMS(0.031)S(0.04)LQIS(0.001)NEK 80.719 0.016992 28038900.0 107183.0 140992.0 122595.0 143085.0 163734.0 137439.0 148393.0 161747.0 129424.0 134432.0 True False 105654.55076504486 140665.54168652298 112515.71233038533 153607.9482175675 154103.4880334293 131561.0543559573 156076.06344747456 169262.35610645416 114846.90622486017 157668.3920806195 0.6701060965410318 0.8921606913743209 0.713622501286456 0.9742469380865139 0.977389862355117 0.8344161605243434 0.9899007745805466 1.07353385084251 0.7284079244376152 1.0 17.26653394522451 -5.766825302087959 24.999230860340848 0.9420386454200923 0.7719828473850014 0.38153728201573067 0.10520294983500769 137.06740309459806 636213.9133132509 0.028224625069169045 0.04327555862686069 1.7107033187604433e-06 5.766825302087959 -0.17005579803509085 DGDSVMVLPTIPEEEAK ddPTM_PC-9_Lapatinib_30min_R1 2 DGDSVMVLPTIPEEEAK 17 0 P30041 P30041 PRDX6 Peroxiredoxin-6 0 ; 145.0 0.0013923 6588400.0 33759.0 40118.0 35473.0 32843.0 34496.0 29655.0 36533.0 38137.0 31852.0 39873.0 False True 33277.5904693576 40025.10923584257 32556.546869739836 35258.38378103624 32467.013101745422 28386.724779181404 38424.49998265815 39908.98424596341 28264.492343570342 46764.99492256714 0.7115918760273191 0.8558775490538514 0.6961734289428778 0.7539482007731767 0.6942588822152953 0.6070079730829389 0.8216508960661907 0.8533943885173981 0.6043942138852002 1.0 15.513141410470402 -11.143528773123967 4.366428200007113 1.005789187996517 0.7375648101277174 0.46412391320669355 0.08590460947885038 0.004907112464269393 0.00042632348893497263 0.0843074563264224 0.020074247950875937 7.185735494616242e-12 11.143528773123967 -0.2682243778687997 DGDSYDPYDFS(ph)DT(ph)EEEMPQVHTPK ddPTM_PC-9_AZD4547_30min_R2 1 DGDSYDPYDFSDTEEEMPQVHTPK 24 0 P25205;J3KQ69;A0A499FHX9;P25205-2;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 2 DGDS(0.031)Y(0.027)DPY(0.095)DFS(0.869)DT(0.849)EEEMPQVHT(0.129)PK 52.769 0.011514 5624400.0 15274.0 16421.0 18662.0 21872.0 20086.0 17520.0 15634.0 18435.0 18853.0 21789.0 True False 20130.81428106377 21728.767119843065 18414.529686465805 16829.748319031456 17297.405609597452 16424.47163038623 17025.39571292886 15586.294344156697 19849.53109083768 21026.173742055445 0.9574169094208127 1.0334151798804139 0.8757908077984742 0.8004189694946484 0.822660642958547 0.7811441031486802 0.8097239146690566 0.7412805836842208 0.9440391454169188 1.0 14.359898717703015 -5.419745741291669 4.215233917959597 0.8276461484240186 0.9938470274231274 0.3757291215877824 0.07558127275020185 0.1925716934575918 5.796043584673009 0.018934435923007902 0.04137286021189279 3.804120442499835e-06 5.419745741291669 0.16620087899910874 DGDSYDPYDFS(ph)DT(ph)EEEMPQVHTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DGDSYDPYDFSDTEEEMPQVHTPK 24 0 P25205;J3KQ69;A0A499FHX9;P25205-2;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 2 DGDS(0.001)Y(0.001)DPY(0.02)DFS(0.865)DT(0.895)EEEMPQVHT(0.218)PK 57.806000000000004 0.0044551 4810400.0 13424.0 14323.0 12651.0 16122.0 20116.0 15635.0 17628.0 15904.0 14822.0 15624.0 True False 15696.41806391445 15744.89278259067 12952.647819184682 15218.736608229217 16174.414203914255 14815.073076155546 15958.14822433206 15486.536851680909 15038.743709530925 18456.50752048404 0.8504544018684851 0.8530808315233057 0.7017930019972157 0.8245729367454071 0.876352917038232 0.8027018686884813 0.8646353166557019 0.8390827373214085 0.8148206638141103 1.0 14.171841960725589 -14.522878745152182 0.2800561504657467 2.281850890510274 0.8137762738994491 0.5605604397887292 0.04644973540528915 175.64505905967658 1.6803878968785118 130.84601961392656 0.05483954131308628 3.0000000008852663e-15 14.522878745152182 -1.4680746166108247 DGDSYDPYDFS(ph)DT(ph)EEEMPQVHTPK ddPTM_PC-9_Lapatinib_30min_R1 1 DGDSYDPYDFSDTEEEMPQVHTPK 24 0 P25205;J3KQ69;A0A499FHX9;P25205-2;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 2 DGDS(0.011)Y(0.016)DPY(0.579)DFS(0.666)DT(0.612)EEEMPQVHT(0.116)PK 46.578 0.034119 6500100.0 7020.0 6848.2 7350.8 5123.7 5943.4 7244.1 5835.8 6779.8 6523.8 4562.8 True False 6919.893512689664 6832.343413652155 6746.445598908566 5500.513990162144 5593.820897173979 6934.286729821886 6137.9491692113 7094.814258876749 5789.0209453404495 5351.473900451167 1.2930818016521146 1.276721804263334 1.2606705600002635 1.027850288067071 1.0452860279674316 1.295771381644462 1.1469642351603038 1.3257682632589511 1.08176196932445 1.0 12.385720577301154 -5.553199207383672 24.5123090192501 1.1489428980774634 1.2808504552839257 0.28758281934432073 0.10251917433100288 221.3244683337683 178926.65995071706 0.028271098088251567 0.04896773174599366 2.7976977438345353e-06 5.553199207383672 0.1319075572064623 DGDSYDPYDFS(ph)DTEEEMPQVHT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 DGDSYDPYDFSDTEEEMPQVHTPK 24 0 P25205;J3KQ69;A0A499FHX9;P25205-2;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 2 DGDS(0.002)Y(0.002)DPY(0.044)DFS(0.911)DT(0.405)EEEMPQVHT(0.637)PK 54.516999999999996 0.006224899999999999 5559600.0 6295.7 6734.0 9272.5 10476.0 10959.0 9546.5 7825.4 9528.0 7702.8 9150.4 True False 8297.601641305031 8910.633809452725 9149.540591456129 8060.920052586572 9437.532016109642 8949.555845860858 8521.845440191482 8055.66653165853 8109.954282422127 8830.047281164994 0.939700703415745 1.0091263982764427 1.036182514104158 0.9128965900081853 1.068797449843836 1.013534306316885 0.9650962411457383 0.9123016304614514 0.918449700685197 1.0 13.10820544757769 -7.50283276608207 5.058027858616386 0.9364729163826933 0.9981338612912948 0.20078100982727953 0.047371121096477786 0.25741046141957724 18.730858990588622 0.02115556174330924 0.013105878503677679 3.1417182434501215e-08 7.50283276608207 0.06166094490860152 DGDSYDPYDFS(ph)DTEEEMPQVHT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 DGDSYDPYDFSDTEEEMPQVHTPK 24 0 P25205;J3KQ69;A0A499FHX9;P25205-2;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 2 DGDS(0.003)YDPY(0.04)DFS(0.724)DT(0.245)EEEMPQVHT(0.988)PK 53.895 0.036655 0.0 4485.1 5390.4 4330.3 3807.7 4413.6 3568.5 3021.8 3120.5 3473.9 3584.4 True False 4421.141651533393 5377.918859985191 3974.2794494413915 4087.730960114842 4154.000725471464 3415.883573579796 3178.254018219046 3265.489821945323 3082.632800211257 4203.958764087218 1.051661517068503 1.2792510968296495 0.9453659449260332 0.9723527725901442 0.988116429913032 0.8125397429585559 0.7560145559394236 0.7767654263978825 0.7332690383514197 1.0 12.037532802882577 -5.993221866685432 0.8450220409168019 0.7956344619696571 1.1673091073289483 0.5750158951984277 0.10375654193734858 0.4660737153732951 0.6663519819756923 0.04838797965057749 0.11513537613532179 1.0157296576187256e-06 5.993221866685432 0.3716746453592912 DGDSYDPYDFS(ph)DTEEEMPQVHTPK ddPTM_PC-9_AZD4547_30min_R2 6 DGDSYDPYDFSDTEEEMPQVHTPK 24 0 P25205;J3KQ69;A0A499FHX9;P25205-2;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 1 DGDSYDPY(0.01)DFS(0.512)DT(0.478)EEEMPQVHTPK;DGDSYDPYDFS(0.727)DT(0.273)EEEMPQVHTPK;DGDSYDPYDFS(0.99)DT(0.01)EEEMPQVHTPK;DGDSYDPY(0.001)DFS(0.988)DT(0.011)EEEMPQVHTPK;DGDSYDPY(0.002)DFS(0.55)DT(0.448)EEEMPQVHTPK;DGDSYDPY(0.002)DFS(0.963)DT(0.036)EEEMPQVHTPK 123.84 1.113e-08 90616200.0 452534.0 411515.0 522217.0 664074.0 596745.0 544086.0 511028.5 559367.0 485121.0 543802.0 True False 596430.3987080608 544529.1761355716 515292.0613694742 510981.99914102454 513897.257318492 510064.21640926565 556509.0465066194 472929.68312492117 510763.5056658495 524763.6575004469 1.136569558854317 1.037665563063707 0.9819507391649648 0.9737373993750499 0.9792927729909618 0.9719884544573884 1.0604946408777278 0.9012241537029809 0.9733210338892695 1.0 19.001308284028106 -4.78195779806185 1.8252128429187247 0.9783770640407022 1.1890854024852469 0.6347514247255555 0.036462637594557624 0.5434401092784362 1.8758272655889414 0.00991179003688695 0.19974684998169903 1.652122333027235e-05 4.78195779806185 0.21070833844454462 DGDSYDPYDFS(ph)DTEEEMPQVHTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 DGDSYDPYDFSDTEEEMPQVHTPK 24 0 P25205;J3KQ69;A0A499FHX9;P25205-2;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 1 DGDS(0.002)Y(0.002)DPY(0.032)DFS(0.48)DT(0.48)EEEMPQVHT(0.005)PK;DGDSYDPYDFS(0.828)DT(0.172)EEEMPQVHTPK;DGDSYDPYDFS(0.994)DT(0.006)EEEMPQVHTPK;DGDSYDPY(0.014)DFS(0.493)DT(0.493)EEEMPQVHTPK;DGDSYDPY(0.017)DFS(0.491)DT(0.491)EEEMPQVHTPK 115.63 1.3714e-08 79570500.0 392861.0 438806.0 439608.0 502471.0 568995.0 502840.0 507668.0 492379.0 468108.0 360523.0 True False 459364.60794155975 482367.7597121747 450089.9219426234 474319.17890296155 457504.5143147843 476470.18520077044 459578.0118419672 479454.57296867407 474953.1939266694 425882.96600150166 1.078617001882954 1.1326298495593596 1.0568394556100569 1.113731275416376 1.0742493850133727 1.1187819735412718 1.0791180876681195 1.1257895037928882 1.115219982583184 1.0 18.700097502149404 -10.503174636072336 4.51514530921988 0.9999976611577083 1.0995902669428548 0.6005548124591282 0.02432975936279988 2473703.0296677276 5754352.076834121 30.249140933796735 0.005457144418943389 3.139246103923962e-11 10.503174636072336 0.0995926057851465 DGDSYDPYDFS(ph)DTEEEMPQVHTPK ddPTM_PC-9_Lapatinib_30min_R1 5 DGDSYDPYDFSDTEEEMPQVHTPK 24 0 P25205;J3KQ69;A0A499FHX9;P25205-2;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 1 DGDSYDPY(0.001)DFS(0.827)DT(0.171)EEEMPQVHTPK;DGDS(0.006)Y(0.001)DPY(0.099)DFS(0.796)DT(0.099)EEEMPQVHTPK;DGDSYDPY(0.013)DFS(0.871)DT(0.115)EEEMPQVHT(0.001)PK;DGDSYDPY(0.001)DFS(0.964)DT(0.034)EEEMPQVHTPK;DGDSYDPY(0.06)DFS(0.774)DT(0.166)EEEMPQVHTPK 104.89 9.1568e-07 31318800.0 351585.0 321828.0 348668.0 321031.0 366129.0 347947.0 297342.0 307091.0 368720.0 303249.0 True False 346571.33342720795 321082.8270390526 320001.86293740093 344640.6906680225 344594.0120573091 333066.11791407294 312736.9138544204 321359.5689508129 327190.8708062682 355665.18559610593 0.9744314244486527 0.9027670968158095 0.8997278223930404 0.9690031654079214 0.9688719222820721 0.9364597138059598 0.8793014512518665 0.903545193528583 0.9199406747047397 1.0 18.440160237068255 -4.739772615928754 24.398443866829137 0.9279925152797489 0.9744316628530769 0.10943785916810367 0.03616394570603963 2874.0838875477084 3236212.7888482204 0.00929037761521817 0.42326711059043054 1.8206538509806332e-05 4.739772615928754 0.04643914757332801 DGDSYDPYDFSDT(ph)EEEMPQVHT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 DGDSYDPYDFSDTEEEMPQVHTPK 24 0 P25205;J3KQ69;A0A499FHX9;P25205-2;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 2 DGDS(0.004)Y(0.002)DPY(0.024)DFS(0.618)DT(0.643)EEEMPQVHT(0.709)PK 53.545 0.024133 4269800.0 18969.0 16879.0 19456.0 14950.0 13477.0 17483.0 14944.0 15516.0 17521.0 13554.0 True False 18698.498581511427 16839.917712542676 17856.402782331865 16049.472871738024 12684.309356801457 16735.292844863543 15717.727198446417 16236.930003942842 15547.600475690555 15896.790840430242 1.176243605970811 1.0593281299086972 1.1232709143355997 1.0096045820090598 0.7979163520565111 1.0527466211797127 0.9887358622390368 1.0213967188048751 0.97803390833755 1.0 13.956447930852233 -5.845164740073834 4.845581130190822 0.9730918089769417 1.11354890878006 0.47187409633613797 0.0690426568023564 0.18882046734885657 7.776247800230998 0.019895677356932987 0.030531484390913657 1.428352041757592e-06 5.845164740073834 0.14045709980311838 DGDSYDPYDFSDT(ph)EEEMPQVHTPK ddPTM_PC-9_AZD4547_30min_R2 4 DGDSYDPYDFSDTEEEMPQVHTPK 24 0 P25205;J3KQ69;A0A499FHX9;P25205-2;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 1 DGDSYDPYDFS(0.299)DT(0.701)EEEMPQVHTPK;DGDSYDPY(0.001)DFS(0.157)DT(0.843)EEEMPQVHTPK;DGDSYDPYDFS(0.013)DT(0.987)EEEMPQVHTPK;DGDSYDPY(0.002)DFS(0.134)DT(0.864)EEEMPQVHTPK 109.85 7.187600000000001e-07 44686500.0 251616.0 241069.0 290411.0 358034.0 349175.0 296478.0 276308.0 309221.0 283197.0 317550.0 True False 331624.65406207484 318989.83988876716 286559.96038882335 275494.79287015833 300698.0784492279 277939.1837918743 300898.8767204783 261437.9996416853 298166.215261866 306432.67115469783 1.0822104993323614 1.0409785571713077 0.9351481984900949 0.8990385778123476 0.9812859618269133 0.9070155043995325 0.981941238793608 0.8531662066467526 0.9730235817816612 1.0 18.225210596765237 -5.1657639989328255 3.3642044309308976 0.9358605509879168 1.0747683118112432 0.555195983568572 0.04345961072393027 0.16184769990441641 3.4034808706113804 0.010600593833823254 0.034636304554829196 6.827095863086524e-06 5.1657639989328255 0.13890776082332645 DGDSYDPYDFSDT(ph)EEEMPQVHTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DGDSYDPYDFSDTEEEMPQVHTPK 24 0 P25205;J3KQ69;A0A499FHX9;P25205-2;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 1 DGDSYDPY(0.004)DFS(0.042)DT(0.61)EEEMPQVHT(0.344)PK;DGDSYDPY(0.001)DFS(0.125)DT(0.873)EEEMPQVHT(0.001)PK;DGDSY(0.001)DPY(0.01)DFS(0.175)DT(0.796)EEEMPQVHT(0.019)PK;DGDSYDPYDFS(0.008)DT(0.529)EEEMPQVHT(0.462)PK 73.672 0.00035579 16637900.0 80341.9 89592.0 85702.9 106905.5 114160.4 106746.6 108420.3 91926.0 90112.4 79238.8 True False 93942.19684514364 98486.10166709906 87746.38216605829 100915.93142730722 91791.48912728857 101148.62037935048 98149.94428900309 89513.03990364823 91430.12337408811 93604.16718600449 1.0036112672042414 1.0521550976613412 0.9374196128650345 1.0781136616148002 0.9806346435932294 1.080599544017673 1.0485638325691795 0.9562933210630823 0.9767740702441565 1.0 16.51428513846878 -7.764242716242403 24.999950509729878 0.9749002680027171 1.0258544444056696 0.20978687952583097 0.04274989105299073 110.06804283190121 981537.3513098315 0.021316978736418805 0.010962980506451144 1.7209065348828347e-08 7.764242716242403 0.05095417640295252 DGDSYDPYDFSDT(ph)EEEMPQVHTPK ddPTM_PC-9_Lapatinib_30min_R1 6 DGDSYDPYDFSDTEEEMPQVHTPK 24 0 P25205;J3KQ69;A0A499FHX9;P25205-2;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 1 DGDSYDPY(0.013)DFS(0.195)DT(0.791)EEEMPQVHTPK;DGDSYDPY(0.001)DFS(0.035)DT(0.964)EEEMPQVHTPK;DGDSYDPYDFS(0.042)DT(0.957)EEEMPQVHTPK;DGDSYDPY(0.002)DFS(0.036)DT(0.962)EEEMPQVHTPK;DGDSYDPY(0.001)DFS(0.066)DT(0.934)EEEMPQVHTPK;DGDSYDPYDFS(0.397)DT(0.602)EEEMPQVHTPK 112.36 5.5592e-07 73570400.0 531147.0 515471.0 608529.0 540371.0 568860.0 535052.0 467420.0 492341.0 602024.0 467921.0 True False 523572.7463795706 514277.4585699438 558498.0946098707 580111.6859648118 535400.773221791 512169.0732271314 491620.7204963745 515216.9602391866 534217.7175262338 548800.5213844595 0.9540310658939487 0.9370936041980713 1.0176704883605925 1.057053817116215 0.9755835724629691 0.933251797820968 0.8958094996997498 0.9388055225229167 0.9734278607800195 1.0 19.065922326571474 -6.621904338359979 5.227475802550748 0.9415142715599192 0.9924539803158055 0.19759188212988765 0.039989517465684764 0.31709650700992315 13.738428448789552 0.014452641803113158 0.014431482710827599 2.388337301805645e-07 6.621904338359979 0.05093970875588627 DGDSYDPYDFSDTEEEMPQVHT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DGDSYDPYDFSDTEEEMPQVHTPK 24 0 P25205;J3KQ69;A0A499FHX9;P25205-2;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 1 DGDSYDPYDFSDT(0.002)EEEMPQVHT(0.998)PK 72.881 0.00044707 5305600.0 31506.0 31728.0 37176.0 49301.0 41825.0 44944.0 44615.0 34929.0 35881.0 31679.0 True False 36839.343528135316 34877.74615695293 38062.41683076512 46538.82480599856 33629.69149327469 42587.057520609815 40388.744215371815 34012.15076033466 36405.69174481707 37422.15192917399 0.9844261120487751 0.9320080315788184 1.0171092486290716 1.2436170131017317 0.8986573395598147 1.1380173326539598 1.0792736957461042 0.9088774698127149 0.9728380081861489 1.0 15.191604901470821 -10.389970477161985 5.051104585820764 0.9999999628081263 1.021824496619129 0.002712391401833214 0.10286293385322567 4.8246790147961443e-08 1.0961078558198323e-08 0.10041925490302141 0.024355200662565343 4.074079719868719e-11 10.389970477161985 0.02182453381100269 DGEEAGAYDGPR ddPTM_PC-9_AZD4547_30min_R2 1 DGEEAGAYDGPR 12 0 H7BZJ3;P30101 H7BZJ3;P30101 PDIA3 Protein disulfide-isomerase A3 0 105.4 0.008274 20702000.0 53637.0 58228.0 75952.0 83700.0 76739.0 83973.0 76338.0 78547.0 70569.0 65416.0 False True 70692.45028109312 77049.06228939907 74944.82685384476 64404.25815210925 66085.1144615601 78722.15503529832 83131.9341136987 66409.3659804978 74299.13327053115 63125.80575108074 1.1198661061032529 1.2205636248544829 1.1872296276006216 1.020252452793549 1.046879539599836 1.2470677260852319 1.3169247207949573 1.0520161317602008 1.1770009489226856 1.0 15.945942277282146 -9.90035475552732 1.2369128446782494 0.9984797320171375 1.1548850347042658 0.20591043427199585 0.09070092282335965 95.16290836019725 80.41511425084715 0.8750154756541818 0.02782717288161148 1.2578974724384685e-10 9.90035475552732 0.15640530268712838 DGEEAGAYDGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DGEEAGAYDGPR 12 0 H7BZJ3;P30101 H7BZJ3;P30101 PDIA3 Protein disulfide-isomerase A3 0 99.788 0.014911 15151000.0 41695.0 44874.0 54718.0 69136.0 62601.0 41606.0 66132.0 51518.0 50042.0 39940.0 False True 48753.13998621221 49328.7941580656 56022.684639170606 65262.534061936254 50334.78343503859 39424.108116822994 59867.498205782154 50165.707087833034 50773.76957983717 47180.80583513398 1.033325716321432 1.0455267409047109 1.1874041497920405 1.3832433106375095 1.066848743765117 0.8355963281887222 1.2688952031675733 1.0632651604792283 1.0761530813453728 1.0 15.525912439170133 -6.488066918732725 24.995132476930205 1.053685167575895 1.1644701629735847 0.14272084701916177 0.13307548359793991 1343.1860115301201 964417.513582004 0.04335394783703997 0.04913203487113862 3.250372098182852e-07 6.488066918732725 0.11078499539768982 DGEEAGAYDGPR ddPTM_PC-9_Lapatinib_30min_R1 2 DGEEAGAYDGPR 12 0 H7BZJ3;P30101 H7BZJ3;P30101 PDIA3 Protein disulfide-isomerase A3 0 ; 139.15 0.00032973 29690000.0 138811.0 179241.0 152893.0 132614.0 173581.0 147082.0 155149.0 165781.0 141227.0 129909.0 False True 136831.52968518029 178825.9784770342 140322.72772404767 142366.87594733533 163371.3068533764 140791.64572488825 163181.85607011264 173483.79047329494 125320.52807376011 152363.5975571381 0.8980591944468027 1.1736791552849255 0.920972791230038 0.934389041935992 1.0722463204645079 0.9240504161244274 1.0710029080858212 1.1386170532514273 0.8225096419554118 1.0 17.21715873227459 -7.29411365550171 24.972008019282 1.019583791745199 0.9941580327489727 0.0018426592545740528 0.10836913033605974 4796.4507190406 3665767.4034077385 0.043962945755479474 0.029643076976159404 5.0802647389031676e-08 7.29411365550171 -0.025425758996226344 DGEQS(ph)PNVSLMQR ddPTM_PC-9_AZD4547_30min_R2 1 DGEQSPNVSLMQR 13 0 F2Z305;Q58WW2;Q58WW2-2;Q58WW2-4;Q58WW2-3 F2Z305 DCAF6 DDB1- and CUL4-associated factor 6 1 DGEQS(0.998)PNVS(0.002)LMQR 93.243 0.0037145000000000004 7206400.0 39178.0 36517.0 50580.0 52195.0 54491.0 49438.0 37909.0 45062.0 43788.0 45475.0 True False 51635.78904697632 48320.406121144224 49909.276151615086 40162.24915471132 46925.86523312627 46346.63404469377 41282.82756053606 38098.703321746114 46102.54428502628 43882.93409151273 1.1766712986715044 1.1011206775822615 1.137327692071253 0.9152133964186998 1.0693420165403675 1.0561425530034814 0.9407490272743738 0.8681895162774603 1.0505802594895959 1.0 15.421372369687976 -4.9080954937651535 0.5576034290296781 0.9678416494280467 1.2955473703679907 0.46602376143690205 0.0689164363572286 3.178328894716663 0.8321300795218635 0.040091406900178476 0.6650406838327693 1.2356757000839161e-05 4.9080954937651535 0.327705720939944 DGEQSPNVS(ph)LMQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DGEQSPNVSLMQR 13 0 F2Z305;Q58WW2;Q58WW2-2;Q58WW2-4;Q58WW2-3 F2Z305 DCAF6 DDB1- and CUL4-associated factor 6 1 DGEQS(0.27)PNVS(0.73)LMQR 94.54700000000001 0.0032939 5723700.0 26130.0 29604.0 27464.0 24654.0 33829.0 31484.0 36786.0 30712.0 29893.0 30077.0 True False 30553.292908975287 32542.88947397988 28118.845917799994 23272.716309346426 27200.45029350842 29832.923615585638 33301.36377242338 29905.84254205381 30330.128573000107 35529.72201059902 0.8599361655534712 0.9159342553896672 0.7914175604698439 0.6550210638406865 0.7655689027173964 0.8396610479160533 0.9372818555261735 0.8417133838855388 0.8536551049837148 1.0 15.116738780419565 -7.017311982397537 5.820227775744231 0.8945843517994635 0.7962257026478388 0.31810445847975133 0.07530906467452153 0.2599411489534599 31.08285714844966 0.031051329680860128 0.02525203595717755 9.609217368610093e-08 7.017311982397537 -0.09835864915162473 DGEQSPNVS(ph)LMQR ddPTM_PC-9_Lapatinib_30min_R1 1 DGEQSPNVSLMQR 13 0 F2Z305;Q58WW2;Q58WW2-2;Q58WW2-4;Q58WW2-3 F2Z305 DCAF6 DDB1- and CUL4-associated factor 6 1 DGEQS(0.047)PNVS(0.953)LMQR 85.271 0.0071982 2779900.0 26559.0 28219.0 25228.0 28082.0 36268.0 39807.0 38026.0 40212.0 33939.0 37288.0 True False 26180.263789675893 28153.660639270187 23153.851222896203 30147.24395880582 34134.78754563146 38104.547404649275 39994.80021735304 42080.39632112329 30116.432426486033 43733.181116863154 0.5986361641454204 0.6437597247736998 0.5294344164222773 0.6893448678761054 0.7805237733431051 0.8712960372772077 0.9145184319082468 0.9622075331926274 0.6886403334349118 1.0 15.416440672276938 -6.331244548058486 1.7417165855456798 0.8881033704991435 0.5959024065503814 0.7130838624561797 0.08252292550807919 0.19272589299272205 1.157232443584181 0.029015373543050175 0.03659583871628929 4.663966817860736e-07 6.331244548058486 -0.29220096394876205 DGETPDPEDPSR ddPTM_PC-9_Lapatinib_30min_R1 1 DGETPDPEDPSR 12 0 P09960-3;P09960-2;P09960-4;P09960 P09960-3 LTA4H Leukotriene A-4 hydrolase 0 132.88 0.00034225 2770600.0 23769.0 21937.0 26298.0 23335.0 24853.0 28368.0 23173.0 20792.0 22146.0 23292.0 False True 23430.049701299253 21886.20622430526 24135.879953215623 25051.13374327804 23391.195402877966 27154.766769037877 24372.7845536402 21758.07222492777 19651.68427228145 27317.991165360872 0.8576783541466432 0.8011645545905624 0.8835159147360675 0.9170196150821953 0.856256057090242 0.9940250219961282 0.8921880238597051 0.7964740925942219 0.7193678390671612 1.0 14.737563778172813 -10.775103323612448 3.8140283124911027 1.0001839412479416 0.8615797559297482 0.2652827664940014 0.07084484722582544 109649295.82627216 122851049201.60535 41343408.03240869 0.0189581245913063 1.678404658999797e-11 10.775103323612448 -0.1386041853181934 DGFPS(ph)GTPALNAK ddPTM_PC-9_AZD4547_30min_R2 2 DGFPSGTPALNAK 13 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 DGFPS(0.978)GT(0.022)PALNAK;DGFPS(0.967)GT(0.033)PALNAK 136.14 5.4000000000000005e-05 9609600.0 42400.0 52114.0 63329.0 66371.0 67351.0 84605.0 66071.0 76482.0 54702.0 74552.0 True False 55882.31802521301 68958.83135518554 62489.21608156651 51070.191371728055 58000.47621288451 79314.63597538979 71951.19100351301 64663.46428151842 57593.43604365367 71941.95717186267 0.7767694989408661 0.9585342693756479 0.8686060059818163 0.7098804839257584 0.8062120978211191 1.1024809317588409 1.0001283511321257 0.8988282613307752 0.8005542010216415 1.0 16.13454578789308 -6.6917569822494904 24.99999999999711 0.9565670884884052 0.8276120857481696 0.34388925620834176 0.09406048797543444 65.55395865845463 23517.69318841973 0.03330396710830815 0.03330395749340214 2.0334945732600453e-07 6.6917569822494904 -0.12895500274023564 DGFPS(ph)GTPALNAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DGFPSGTPALNAK 13 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 DGFPS(0.997)GT(0.003)PALNAK;DGFPS(0.999)GT(0.001)PALNAK;DGFPS(0.988)GT(0.012)PALNAK 108.97 0.0008384999999999999 2404700.0 57042.0 78961.0 87068.0 75416.0 98559.0 81161.0 113136.0 65233.0 81439.0 73972.0 True False 66698.08396914527 86799.7262449308 89144.031327229 71190.68602197088 79247.07146170158 76904.7742842252 102418.93904629191 63520.70287007673 82629.89130754874 87382.53803797007 0.763288472350885 0.9933303402930913 1.0201584129828491 0.8147015138314775 0.9068982572612687 0.8800931629018146 1.1720755810707641 0.7269267326897197 0.9456110243861745 1.0 16.41505738921824 DGFPS(ph)GTPALNAK ddPTM_PC-9_Lapatinib_30min_R1 1 DGFPSGTPALNAK 13 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 DGFPS(0.997)GT(0.003)PALNAK 168.0 0.00027467 4520700.0 15661.0 23875.0 20522.0 20018.0 34011.0 33017.0 31946.0 32450.0 34772.0 25087.0 True False 15437.671268124344 23819.71890437561 18834.760377210856 21490.190498090415 32010.539848198747 31604.939876386175 33600.0075670215 33957.74546454915 30855.611194607172 29423.254523673706 0.524675856496545 0.8095541873252146 0.6401317829085347 0.7303811507594983 1.0879333495362769 1.07414833566277 1.1419541485455735 1.1541124873601945 1.0486811093511428 1.0 14.844669212324408 -6.229426397093214 3.953793498795497 1.09719896440076 0.6750953679968663 0.8701999058869854 0.07741715572556401 0.07152242044081385 2.500369790292229 0.022722206753057878 0.028772289364527213 5.896218959223719e-07 6.229426397093214 -0.4221035964038937 DGFQHPAR ddPTM_PC-9_AZD4547_30min_R2 1 DGFQHPAR 8 0 F5H1H2;F5H2E6;A0A0C4DGG8;Q8IX12-2;Q8IX12;F5H3E1 F5H1H2 CCAR1 Cell division cycle and apoptosis regulator protein 1 0 76.47800000000001 0.020899 1632400.0 12059.0 11357.0 17162.0 22668.0 17749.0 18055.0 14934.0 21250.0 13525.0 16289.0 False True 15893.511157218016 15027.928151760423 16934.420666548413 17442.242817108843 15284.857720041073 16926.017995811835 16263.097069008549 17966.30077642149 14239.903888165245 15718.72706798573 1.0111194811434996 0.9560524899225298 1.0773404610503532 1.1096472851566581 0.9723979336196811 1.076805896724614 1.0346319392574437 1.1429870051636295 0.9059196604518697 1.0 13.940196769724718 -5.259472717235483 24.919287346435556 1.0462735929298033 0.9835859858101598 0.09733096075854042 0.06649577637018085 317.33037619745306 4020767.120465139 0.016156862038049318 0.038414356283771454 5.502084840099789e-06 5.259472717235483 -0.0626876071196435 DGFQHPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DGFQHPAR 8 0 F5H1H2;F5H2E6;A0A0C4DGG8;Q8IX12-2;Q8IX12;F5H3E1 F5H1H2 CCAR1 Cell division cycle and apoptosis regulator protein 1 0 91.069 0.0075553 773030.0 12018.0 14000.0 11679.0 12565.0 15449.0 13342.0 15097.0 12432.0 11704.0 10371.0 False True 14052.410033680255 15389.827477223293 11957.471652854141 11861.023786279635 12421.879351574433 12642.322032751352 13666.902867185212 12105.673172792824 11875.148858207387 12251.180203209178 1.1470250049868052 1.2561914217204928 0.9760261015279083 0.9681535647620837 1.0139332819805018 1.0319268693345736 1.1155580638349591 0.9881230193334158 0.9693065207788478 1.0 13.580633115822353 -5.265033640395791 24.999805682310022 1.0109563206196672 1.20160821938342 0.7247521181983227 0.0477253773302708 150.35894317128717 1045826.2185803045 0.01303996882577586 0.02895566303528262 5.432082530199927e-06 5.265033640395791 0.19065189876375288 DGFQHPAR ddPTM_PC-9_Lapatinib_30min_R1 2 DGFQHPAR 8 0 F5H1H2;F5H2E6;A0A0C4DGG8;Q8IX12-2;Q8IX12;F5H3E1 F5H1H2 CCAR1 Cell division cycle and apoptosis regulator protein 1 0 ; 98.458 0.0046162 3020300.0 31922.0 34079.0 37125.0 33619.0 34419.0 37775.0 31170.0 34289.0 36886.0 33109.0 False True 31466.786426222174 34000.09216930751 34072.72580664427 36091.45340969633 32394.542090357572 36159.4513078259 32783.83008401866 35882.192118148756 32731.51025320027 38831.846535030636 0.8103345381177184 0.875572376879777 0.8774428425881546 0.9294292347683707 0.8342261566452706 0.9311803206475401 0.8442511239954557 0.9240403256584524 0.8429037806294587 1.0 15.24495269157543 -14.522878745280336 0.30469204671123656 2.0426046383415972 0.8713232007582382 0.4585130811786774 0.04067213579129544 248.3126989917441 2.2744356002282293 165.86146053087873 0.037121704881097554 3.0000000000000132e-15 14.522878745280336 -1.171281437583359 DGFYEAELCPDR ddPTM_PC-9_AZD4547_30min_R2 1 DGFYEAELCPDR 12 0 Q04206;Q04206-4;Q04206-3;Q04206-2;A0A087X0W8;E9PKH5;Q2TAM5;E9PQS6;A0A087WVP0;E9PKV4;E9PMD5;E9PI38;E9PNV4;E9PRX2;E9PJR1 Q04206 RELA Transcription factor p65 0 111.5 0.004912 1947200.0 8037.3 7117.9 9206.8 13030.0 12753.0 9197.9 8893.7 10901.0 8151.8 8644.0 False True 10592.994213774631 9418.621976879052 9084.711816383744 10026.134811493215 10982.46608280376 8622.753858968586 9685.222070620151 9216.500930059794 8582.687505770467 8341.376191028836 1.2699336381887936 1.1291448510629212 1.0891142670383775 1.201976098653402 1.3166251984433242 1.0337327632150644 1.1611060152204409 1.1049137119570456 1.0289294367278583 1.0 13.026069709121273 -8.013035126202722 0.8563711813504928 0.996694833539014 1.1811796839798985 0.41960900603011086 0.07584630588458467 0.6111100581206514 0.8726193436222913 0.07230708434392874 0.028671658372267834 9.704314745344856e-09 8.013035126202722 0.18448485044088447 DGFYEAELCPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DGFYEAELCPDR 12 0 Q04206;Q04206-4;Q04206-3;Q04206-2;A0A087X0W8;E9PKH5;Q2TAM5;E9PQS6;A0A087WVP0;E9PKV4;E9PMD5;E9PI38;E9PNV4;E9PRX2;E9PJR1 Q04206 RELA Transcription factor p65 0 116.55 0.0024052 0.0 9742.2 11551.0 14387.0 16705.0 15112.0 12446.0 12304.0 13676.0 11626.0 8937.2 False True 11391.362042779157 12697.706942100453 14730.04064300133 15769.07300834073 12150.912082399691 11793.309850069203 11138.476046754122 13317.01949091977 11796.008255768887 10557.44361316373 1.0789886700011015 1.2027255278226727 1.395227972104433 1.4936450135219088 1.1509331735619328 1.117061125987404 1.0550353338251242 1.261386750322324 1.1173167187045954 1.0 13.365972921339264 -6.493213221121586 24.91149450878825 1.124267532344987 1.297143351565156 0.34082455049297655 0.11994879299757495 856.7622353574831 719463.02569535 0.03963012271980585 0.04486546571392487 3.2120831478312894e-07 6.493213221121586 0.17287581922016892 DGFYEAELCPDR ddPTM_PC-9_Lapatinib_30min_R1 1 DGFYEAELCPDR 12 0 Q04206;Q04206-4;Q04206-3;Q04206-2;A0A087X0W8;E9PKH5;Q2TAM5;E9PQS6;A0A087WVP0;E9PKV4;E9PMD5;E9PI38;E9PNV4;E9PRX2;E9PJR1 Q04206 RELA Transcription factor p65 0 108.9 0.0063414 2381500.0 6071.9 10309.0 8144.0 7933.0 11304.0 10904.0 9692.4 10785.0 9917.4 9666.2 False True 5985.313592549912 10285.130143883069 7474.4317567491125 8516.41928371222 10639.120944519085 10437.66133846549 10194.225046722571 11286.110472578212 8800.397977148197 11336.989790598112 0.527945574892693 0.9072187885723102 0.6592959766928378 0.7512063996718933 0.9384431970947194 0.920673082648584 0.8992003375690389 0.9955120963360049 0.7762552617315103 1.0 13.468750004778498 -6.198035498516303 4.641830626474845 0.9204847793154118 0.7178732533729545 0.4938465807751723 0.10454292108317915 0.19186271794658885 8.366175806671329 0.02951614100166846 0.038139398177571324 6.338179019072196e-07 6.198035498516303 -0.20261152594245735 DGGAILMRLRS(ph)T(ph)PS(ph)SK ddPTM_PC-9_Lapatinib_30min_R1 1 DGGAILMRLRSTPSSK 16 2 Q8TER5-4;Q8TER5-3;Q8TER5;Q8TER5-2 Q8TER5-4 ARHGEF40 Rho guanine nucleotide exchange factor 40 3 DGGAILMRLRS(0.75)T(0.75)PS(0.75)S(0.75)K 60.55 0.020116 3890800.0 7233.2 3631.1 36849.0 6226.6 16664.0 23546.0 7131.2 9974.6 32120.0 9550.7 True False 7130.053241593571 3622.6924110441187 33819.41746125344 6684.52493532869 15683.856282684528 22538.992468406843 7500.418642770421 10438.056330067555 28502.307361405226 11201.525769492186 0.6365251831150148 0.3234106215164607 3.019179543679845 0.5967512884302125 1.4001535688468578 2.012135929713496 0.669589018238758 0.9318423708398751 2.5445022354929923 1.0 13.451407635953585 DGGAWGTEQR ddPTM_PC-9_AZD4547_30min_R2 2 DGGAWGTEQR 10 0 P09382 P09382 LGALS1 Galectin-1 0 ; 140.11 0.00056398 97245000.0 65627.0 72628.0 95654.0 124689.0 100606.0 102251.0 91070.0 111191.0 97272.0 90627.0 False True 86495.02087360027 96103.58068205112 94385.56546078663 95943.87747584637 86638.59348596857 95857.22880585748 99175.05357403323 94008.98586499204 102413.59933527622 87454.17631471179 0.9890324798479616 1.0989021305993858 1.0792573829879961 1.097075994753911 0.9906741694552325 1.0960852053640817 1.1340230707467052 1.0749513611184465 1.171054415591676 1.0 16.416239660261937 -6.970177061082797 24.99943018065571 1.1032247896193905 1.0563410566414984 0.13050734856322588 0.05462843492807661 391.03825511566856 327791.51887205854 0.018332751607204722 0.01616787731579823 1.0710825377758031e-07 6.970177061082797 -0.04688373297789217 DGGAWGTEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DGGAWGTEQR 10 0 P09382 P09382 LGALS1 Galectin-1 0 ;;;;; 140.11 0.00056398 73732000.0 235326.6 233974.2 210642.4 258424.7 300783.0 255808.2 273102.6 232328.0 238141.9 193271.5 False True 275162.7454677871 257201.61229438186 215664.91368175007 243946.00188318169 241846.73033883132 242393.16766740094 247232.34463639988 226229.6361718636 241624.27476728836 228310.0930136478 1.205214985617559 1.126545081294356 0.9446140152413594 1.0684854036155083 1.0592905777686068 1.0616839775581506 1.0828796106776626 0.9908875826980639 1.0583162206186156 1.0 17.800635113319956 -5.019379392053951 5.942942420935811 1.0374844707954174 1.188833686644745 0.6437304319111837 0.04127019491204523 0.08621064072088314 11.644781223327154 0.010326604307218552 0.03270558761909163 9.563582484499634e-06 5.019379392053951 0.1513492158493277 DGGAWGTEQR ddPTM_PC-9_Lapatinib_30min_R1 2 DGGAWGTEQR 10 0 P09382 P09382 LGALS1 Galectin-1 0 ; 114.89 0.0053886 83444000.0 116588.0 98222.0 119333.0 94194.0 105346.0 104165.0 98089.0 103228.0 103098.0 86778.0 False True 114925.43374037926 97994.5729937416 109521.90137870099 101121.34098197283 99149.75539820486 99710.1057704748 103167.56846683689 108024.34973234145 91486.01756993003 101777.46167558328 1.1291835328602051 0.9628317643261759 1.0760918927984586 0.9935533792766237 0.9741818450360428 0.9796874880639271 1.013658296919259 1.0613779117096689 0.8988828770513325 1.0 16.635058590576556 -4.75138526522849 24.97684372050175 0.9993545997662043 1.1291838004067893 0.41543930705213894 0.047353060206508216 411.58069268066555 1022395.370416927 0.011267551434094655 0.14976808181554538 1.7726162847052977e-05 4.75138526522849 0.129829200640585 DGGEALVS(ph)PDGTVTEAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DGGEALVSPDGTVTEAPR 18 0 Q96HN2-2;Q96HN2 Q96HN2-2 AHCYL2 Putative adenosylhomocysteinase 3 1 DGGEALVS(0.822)PDGT(0.134)VT(0.044)EAPR 104.03 0.0040553 0.0 9354.0 15558.0 12860.0 11149.0 12565.0 9258.5 11433.0 8482.2 9379.9 7055.4 True False 10937.447450078647 17102.495420760013 13166.631171821582 10524.357675545683 10102.978448607217 8772.967961342254 10349.983472248034 8259.55123763379 9517.063292472612 8334.488169484333 1.3123118333918473 2.052015081547373 1.5797768146134665 1.2627479290305166 1.212189428212039 1.0526102842719676 1.241825924013328 0.9910088141795059 1.1418893516842614 1.0 13.02487788903038 -5.816443822241489 2.4643845780274343 1.1141402615833353 1.710121153865391 0.6361007181041052 0.18354305514800573 0.16304014193314254 2.0173586478561805 0.052031857964742766 0.09126584976672719 1.5260057770981652e-06 5.816443822241489 0.5959808922820558 DGGQTES(ph)NEEGKENR ddPTM_PC-9_Lapatinib_30min_R1 2 DGGQTESNEEGKENR 15 1 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5;Q5VU81;Q5VU80;Q5VU79;Q5VU78;Q5VU77 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 DGGQT(0.023)ES(0.977)NEEGKENR;DGGQTES(1)NEEGKENR 111.34 0.0020862 13451400.0 15123.2 13438.4 14466.3 14547.7 16699.800000000003 18120.4 12574.4 15249.6 12660.5 15942.7 True False 14907.540394744778 13407.284210452828 13276.936655532874 15617.586387704567 15717.550597070034 17345.432732715508 13225.440904988274 15958.152087401828 11234.541169024613 18698.374452687556 0.7972639778107602 0.7170293997682655 0.7100583363076544 0.8352376527286745 0.8405837971017271 0.927643885654585 0.707304313455299 0.853451305501486 0.6008298313551983 1.0 14.190625234101809 -5.766550427194965 24.768736446002688 0.817672324496917 0.7390084506740918 0.11098008420003813 0.10553075619382488 254.20637228976994 1231923.067604108 0.028435062334128337 0.04366629848693056 1.7117864046667751e-06 5.766550427194965 -0.07866387382282514 DGGQTESNEEGKENR ddPTM_PC-9_AZD4547_30min_R2 2 DGGQTESNEEGKENR 15 1 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5;Q5VU81;Q5VU80;Q5VU79;Q5VU78;Q5VU77 F8W726 UBAP2L Ubiquitin-associated protein 2-like 0 ; 80.411 0.012799 7843200.0 13571.3 11006.0 14890.1 18810.6 20761.9 16065.8 16688.9 20470.1 16106.4 17169.5 False True 17886.691099423893 14563.474265939523 14692.647544981497 14474.106790872944 17879.4685614807 15061.2029862705 18174.17976931678 17306.916401102357 16957.7514221327 16568.401030989065 1.0795665234061596 0.8789909321183388 0.8867872957384836 0.8735970818065658 1.079130600957778 0.909031774285307 1.096918147703228 1.0445737261388104 1.0234995755121694 1.0 14.016146758453319 -6.260019144822765 24.996477656515893 1.0254992558737004 0.9230431236337574 0.2927894716471673 0.0726355782413236 157.7865193481548 2777079.6689856374 0.021705933691908673 0.026538119951059494 5.495166492101087e-07 6.260019144822765 -0.10245613223994299 DGGQTESNEEGKENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DGGQTESNEEGKENR 15 1 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5;Q5VU81;Q5VU80;Q5VU79;Q5VU78;Q5VU77 F8W726 UBAP2L Ubiquitin-associated protein 2-like 0 ;; 105.58 0.0013377 10371400.0 22845.800000000003 24387.100000000002 25548.1 27747.2 37298.0 27841.899999999998 32138.3 31521.6 27054.3 24152.3 False True 26713.142714882048 26808.090119270877 26157.26359570879 26192.614341636126 29989.72464593329 26381.821751136238 29093.927562857418 30694.191399895928 27449.9179557929 28530.92080049841 0.9362874371168347 0.9396153144416763 0.9168040449382148 0.9180430777116231 1.0511306261594402 0.9246747392280228 1.0197332138803306 1.0758219692425675 0.9621111827317319 1.0 14.80023868843458 -6.244410670648374 24.852188614442255 1.0060322564150708 0.92776206337784 0.47481117340637846 0.04013028554401012 690.9550322664227 1008399.4448617264 0.01187536605805583 0.015290960987081173 5.696253774304979e-07 6.244410670648374 -0.07827019303723082 DGGQTESNEEGKENR ddPTM_PC-9_Lapatinib_30min_R1 3 DGGQTESNEEGKENR 15 1 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5;Q5VU81;Q5VU80;Q5VU79;Q5VU78;Q5VU77 F8W726 UBAP2L Ubiquitin-associated protein 2-like 0 ;; 138.31 6.4996e-05 10380100.0 19785.8 21191.3 21447.7 17581.5 19522.5 21870.2 16566.899999999998 19229.0 21275.8 15216.8 False True 19503.65086372866 21142.23284683958 19684.35289651619 18874.50216016468 18374.224932711753 20934.862527926252 17424.653019535737 20122.449538915742 18879.49535989368 17847.003604888527 1.0928249523290485 1.1846376744748595 1.1029500151568519 1.0575726087148158 1.029541167777812 1.173018339178904 0.9763349302379755 1.127497365070512 1.057852386757088 1.0 14.123394255078919 -1.522878756133242 0.0644668524886863 0.9061953148669206 1.4711651213183288 0.2426212248392593 0.0572229445358859 434.19145540982294 2.088722926717082 3.474905234940826 22.647929291729547 0.029999999250307934 1.522878756133242 0.5649698064514082 DGGRS(ph)SPGGQDEGGFMAQGK ddPTM_PC-9_Lapatinib_30min_R1 2 DGGRSSPGGQDEGGFMAQGK 20 1 A0A1B0GTU4;F5GZ78;P49023;A0A1B0GV30 A0A1B0GTU4 PXN Paxillin 1 DGGRS(0.5)S(0.5)PGGQDEGGFMAQGK;DGGRS(0.786)S(0.214)PGGQDEGGFMAQGK 108.34 4.7567e-05 18447800.0 181125.0 68033.0 92225.0 78025.0 82091.0 81965.0 70026.0 58407.0 89476.0 53231.0 True False 178542.1242857426 67875.47376843511 84642.61649879502 83763.21878376992 77262.56877711571 78459.54801974716 73651.6036401506 61120.802445236455 79398.27065594944 62431.90742415095 2.8597896756983587 1.0871920556151131 1.3557589378736834 1.34167322831734 1.237549387242135 1.2567219432638403 1.1797109311393466 0.9789994406224515 1.271757886821111 1.0 15.929995923340424 -4.75901912843295 24.999998645459463 1.202453214190956 2.8597918398745934 0.9412381772574968 0.12513450014608166 14.212521645147328 146776.85101880008 0.031568236760215654 0.20686449915484428 1.7417301574681e-05 4.75901912843295 1.6573386256836373 DGGRSS(ph)PGGQDEGGFMAQGK ddPTM_PC-9_AZD4547_30min_R2 1 DGGRSSPGGQDEGGFMAQGK 20 1 A0A1B0GTU4;F5GZ78;P49023;A0A1B0GV30 A0A1B0GTU4 PXN Paxillin 1 DGGRS(0.258)S(0.742)PGGQDEGGFMAQGK 63.443000000000005 0.017804 4834100.0 15435.0 10374.0 21378.0 45077.0 34190.0 21116.0 17915.0 23244.0 14585.0 24107.0 True False 20343.008932055724 13727.19262537312 21094.513751862934 34685.194082707574 29443.30866235868 19795.613181919838 19509.400294046365 19652.17389398311 15355.93332413237 23263.02126759972 0.8744783705454917 0.5900864065533948 0.9067830661034111 1.4910012626354958 1.265670022980495 0.8509476458026017 0.8386443046079606 0.8447816673474942 0.6601005581987672 1.0 14.505750857475164 -6.966247299307023 24.986262318601316 0.8260678249296136 1.0244273850890688 0.1345587537431826 0.23646819719140008 430.19451963358404 318460.8250615263 0.09495170009455826 0.08373917822906075 1.0808183281457361e-07 6.966247299307023 0.19835956015945522 DGGRSS(ph)PGGQDEGGFMAQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DGGRSSPGGQDEGGFMAQGK 20 1 A0A1B0GTU4;F5GZ78;P49023;A0A1B0GV30 A0A1B0GTU4 PXN Paxillin 1 DGGRS(0.252)S(0.748)PGGQDEGGFMAQGK;DGGRS(0.279)S(0.721)PGGQDEGGFMAQGK 98.07700000000001 0.00063714 45609000.0 59759.0 27043.0 40738.0 93325.0 90554.0 111384.0 87688.0 130367.0 102323.0 65848.0 True False 69875.01840594933 29727.650319039272 41709.34841972533 88096.30281373217 72810.59374732796 105542.82695967436 79381.55783385696 126945.00438525427 103819.2802989024 77785.72114751877 0.8983013511365797 0.3821736159347484 0.5362082886732457 1.1325510841078354 0.9360406083944945 1.356840630936813 1.0205158049934606 1.6319833834863613 1.3346830082350412 1.0 16.24721772858757 -6.084269042799999 1.2749638316027903 1.2886505829145614 0.5749130612388942 0.5594821240603998 0.23585057086215858 0.3093325554693013 1.0219580408509432 0.08784647499566611 0.15053057677221543 8.236277245527103e-07 6.084269042799999 -0.7137375216756672 DGGRSS(ph)PGGQDEGGFMAQGK ddPTM_PC-9_Lapatinib_30min_R1 3 DGGRSSPGGQDEGGFMAQGK 20 1 A0A1B0GTU4;F5GZ78;P49023;A0A1B0GV30 A0A1B0GTU4 PXN Paxillin 1 DGGRS(0.274)S(0.726)PGGQDEGGFMAQGK;DGGRS(0.18)S(0.82)PGGQDEGGFMAQGK;DGGRS(0.375)S(0.625)PGGQDEGGFMAQGK 77.027 0.0031152 44070600.0 204510.0 81110.0 112306.0 100536.0 92679.0 85694.0 52483.0 55374.3 108926.0 54685.0 True False 201593.64989745873 80922.19477838337 103072.63419369687 107929.75281826423 87227.8034339246 82029.06738247068 55200.312938708754 57947.19213182082 96657.60683836935 64137.22938681778 3.1431611846160066 1.2617039362635056 1.6070640278527768 1.6827941251925544 1.360018265021168 1.278961816197976 0.8606594557708499 0.9034876106408611 1.5070436899514017 1.0 15.968874412838959 -3.1365743588305106 1.4560603855227146 1.2490256804909268 199.99999999100643 0.7903885011148433 0.2847825463611192 71.22913428578977 1.8593464577258763 0.08652069092204176 45894.86685031643 0.0007301727837861645 3.1365743588305106 198.75097431051552 up DGGS(ph)GNSTIIVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DGGSGNSTIIVSR 13 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 DGGS(0.745)GNS(0.249)T(0.006)IIVSR 73.80199999999999 0.020442 60407000.0 18645.0 18634.0 20924.0 18538.0 21539.0 22459.0 22275.0 19232.0 20090.0 15467.0 True False 21801.23024446401 20483.86037218422 21422.907514711886 17499.3759610069 17318.587569005227 21281.21050319012 20164.95074296553 18727.180377988385 20383.77824345407 18271.04466329538 1.1932120273484093 1.1211105193855804 1.17250589167177 0.9577654854164589 0.9478706821726762 1.164750614722203 1.1036561463546095 1.0249649499029103 1.1156328835648326 1.0 14.157271503250431 -5.730591664883646 24.999855144932923 1.0493818256788259 1.1581596833801526 0.3886047323298196 0.06721965589255381 240.42543923189822 194845.84977327284 0.019295205971926147 0.033416095507270815 1.8595520332277478e-06 5.730591664883646 0.10877785770132675 DGGS(ph)YEQYR ddPTM_PC-9_AZD4547_30min_R2 1 DGGSYEQYR 9 0 H0Y872;Q8IWU5 H0Y872 SULF2 Extracellular sulfatase Sulf-2 1 DGGS(0.972)Y(0.027)EQY(0.001)R 83.081 0.014837000000000001 10553000.0 13457.0 16093.0 19846.0 20905.0 17244.0 19304.0 14491.0 24404.0 18767.0 17512.0 True False 17736.046077011582 21294.747534232658 19582.82907285395 16085.675229030383 14849.968253106552 18096.917828366193 15780.67092721327 20632.92254813128 19758.98530641014 16898.91021023796 1.0495378611022181 1.2601254914847435 1.1588220085926002 0.9518764836850314 0.8787530123753137 1.0708925962221185 0.9338277279947189 1.2209617242436808 1.169246126560247 1.0 14.044642591442711 -5.67813653227994 8.867713602703418 1.032659063659593 1.1677125140683424 0.21112284377201607 0.10916533350326604 0.45329146473040965 43.56408697253383 0.03162661512266883 0.05482954163814716 2.0982801285070917e-06 5.67813653227994 0.1350534504087495 DGGS(ph)YEQYR ddPTM_PC-9_Lapatinib_30min_R1 1 DGGSYEQYR 9 0 H0Y872;Q8IWU5 H0Y872 SULF2 Extracellular sulfatase Sulf-2 1 DGGS(0.934)Y(0.066)EQYR 79.036 0.020731 4822700.0 20394.0 14451.0 28608.0 13023.0 14641.0 17726.0 15506.0 20278.0 20266.0 13166.0 True False 20103.177820198453 14417.539597366791 26255.96067007351 13980.754863454466 13779.845165313507 16967.900301324207 16308.824808559302 21220.189908478515 17983.429669559082 15441.725557407744 1.3018737928906206 0.9336741249393836 1.7003255609265722 0.9053881194480614 0.8923772873753092 1.0988344688708913 1.056153002326582 1.3742110510634422 1.1645997464921933 1.0 13.91454635715648 -4.4576247655931995 20.528309766164007 1.1364565809232579 4.918727710621604 0.04627182205816083 0.23576259329858087 594.6131613069537 194380.06839778248 0.05669876594007982 3977.5580313525065 3.4863841172041826e-05 4.4576247655931995 3.782271129698346 DGGSGNS(ph)TIIVSR ddPTM_PC-9_AZD4547_30min_R2 1 DGGSGNSTIIVSR 13 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 DGGS(0.106)GNS(0.864)T(0.03)IIVSR 122.75 0.00017713 7976100.0 18600.0 23647.0 62594.0 87705.0 68089.0 41929.0 25924.0 68659.0 31184.0 47427.0 True False 24514.413095966083 31290.43030771141 61763.96266180698 67485.96727874236 58636.01765169172 39307.17300173886 28231.185778557512 58049.32917686222 32832.322576602215 45766.5951656553 0.5356398702423569 0.6836958308664556 1.3495424433093204 1.4745682311404709 1.2811968519715018 0.8588616404489755 0.616851344880973 1.2683777101344056 0.7173861734254732 1.0 15.482007345284389 -8.292364092169741 24.880906376273945 0.8586932367971314 1.015697369964395 0.0336561931412066 0.319475120404209 3377.1368186606323 2717090.8715798054 0.3336123996900359 0.08617339470021335 5.100771958243198e-09 8.292364092169741 0.15700413316726358 DGGSGNS(ph)TIIVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DGGSGNSTIIVSR 13 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 DGGS(0.41)GNS(0.585)T(0.005)IIVSR;DGGS(0.033)GNS(0.885)T(0.082)IIVSR;DGGS(0.17)GNS(0.761)T(0.069)IIVSR 101.72 0.0019304000000000003 12148500.0 65613.0 95044.0 86969.0 72037.0 92160.0 69000.0 84707.0 65007.0 50474.0 62094.0 True False 76719.98498417909 104479.34019608676 89042.67079176918 68001.00043710526 74101.9095760956 65381.51853244208 76682.93973442788 63300.63513060997 51212.086762573446 73351.1506641665 1.04592749110967 1.424372204799331 1.2139232988920008 0.927061127485831 1.0102351347610945 0.8913495962972297 1.0454224513193495 0.862980806128425 0.6981770060710386 1.0 16.162531977274508 -5.73954920426901 4.86233825397037 0.9201262543354626 1.2538582540753955 0.561002856480987 0.12496082294675967 0.13001297425576386 7.72942081800645 0.034474121599380285 0.05824204684914072 1.8215906806111696e-06 5.73954920426901 0.33373199973993295 DGGSGNS(ph)TIIVSR ddPTM_PC-9_Lapatinib_30min_R1 2 DGGSGNSTIIVSR 13 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 DGGSGNS(0.973)T(0.027)IIVSR;DGGS(0.275)GNS(0.687)T(0.038)IIVSR 158.14 0.00024112 12698900.0 53318.0 42896.0 87158.0 45660.0 54958.0 56231.0 41033.0 49310.0 70638.0 37236.0 True False 52557.67554267633 42796.67694752237 79992.20567960941 49017.98871729484 51725.47849158526 53826.131210863256 43157.48796398905 51601.12261500521 62682.004588883596 43672.19298614878 1.2034585842608292 0.9799525515262287 1.8316507647092513 1.1224073115092148 1.1844030481361603 1.232503511512118 0.9882143536432215 1.1815555640031907 1.4352841087866604 1.0 15.414427356987868 DGGSGNSTIIVS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 DGGSGNSTIIVSR 13 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 DGGSGNSTIIVS(1)R 81.327 0.011759 1859700.0 9203.4 8668.1 9682.0 8654.4 6210.6 10239.0 7416.3 8621.6 8426.5 5062.9 True False 9072.15782830314 8648.029547016482 8885.983333600801 9290.873446232072 5845.304718509399 9801.101838274775 7800.279725765406 9022.191010698214 7477.4188350212 5938.0155191098065 1.5278097201172667 1.456383790036464 1.4964567379461713 1.5646428367073224 0.9843869049681592 1.6505685791377152 1.3136172683723095 1.5193949867026904 1.2592454180958712 1.0 12.535765148500886 -13.091744531303835 0.19778475887600594 1.569394849577122e-12 1.5014534188863669 0.36646347188828465 0.17579474791293842 82.1459229503631 1.3452677582007757 33.73569796360138 0.4385070091877511 8.095719804758043e-14 13.091744531303835 1.5014534188847974 DGGSY(ph)EQYR ddPTM_PC-9_Lapatinib_30min_R1 1 DGGSYEQYR 9 0 H0Y872;Q8IWU5 H0Y872 SULF2 Extracellular sulfatase Sulf-2 1 DGGS(0.128)Y(0.871)EQY(0.002)R 93.162 0.0093796 7779700.0 12422.0 16891.0 13992.0 14742.0 15857.0 19419.0 15936.0 17894.0 14432.0 12361.0 True False 12244.860002084188 16851.889927279957 12841.631770681926 15826.175857870358 14924.322436061486 18588.49463789996 16761.088104553153 18725.420565258642 12806.51618430261 14497.582380002821 0.8446139281108058 1.1623931139390895 0.8857774651030765 1.091642416165893 1.029435256505063 1.2821789282287452 1.1561298749833275 1.2916236703774466 0.8833552966712039 1.0 13.823524715707933 -6.2350429055377985 2.0765361538275067 1.1393861157393446 0.9881275973530578 0.14037740089369533 0.1424774340854236 0.5626312257000763 4.763420531671986 0.04610279481076064 0.060861230219968115 5.820457125089214e-07 6.2350429055377985 -0.1512585183862868 DGIVLGADTR ddPTM_PC-9_AZD4547_30min_R2 1 DGIVLGADTR 10 0 Q5TBG5;Q99436-2;Q99436 Q5TBG5 PSMB7 Proteasome subunit beta type;Proteasome subunit beta type-7 0 91.265 0.037697 5848500.0 24309.0 24883.0 34942.0 42818.0 39026.0 41153.0 39122.0 38725.0 29390.0 31213.0 False True 32038.75634138921 32925.94313641406 34478.6462493028 32946.97163150551 33607.913537794964 38579.69640441121 42603.78221064368 32740.941061972808 30943.495399125804 30120.24237049781 1.0636951704203599 1.0931500062783153 1.1447001596200288 1.0938481578679602 1.115791603679566 1.2808561076586578 1.4144568189920428 1.087007888556764 1.0273322179317639 1.0 14.878445758633275 -6.551433727855965 24.611215776612326 1.1848373447609237 1.102104337547606 0.04609731454152355 0.11572641444460277 455.8193746591904 392861.96560193057 0.04035587506240476 0.04035643593174412 2.8090940000854427e-07 6.551433727855965 -0.08273300721331767 DGIVLGADTR ddPTM_PC-9_Lapatinib_30min_R1 2 DGIVLGADTR 10 0 Q5TBG5;Q99436-2;Q99436 Q5TBG5 PSMB7 Proteasome subunit beta type;Proteasome subunit beta type-7 0 ; 134.77 0.00051662 13247200.0 94310.0 103693.0 112881.0 113970.0 120554.0 113992.0 106965.0 89680.0 108924.0 108857.0 False True 92965.12210566398 103452.90522937868 103600.35991326075 122351.73399277501 113463.25073828328 109116.82788833058 112503.12431623536 93846.86019293581 96655.83209943022 127672.78740716517 0.7281514251677303 0.8102972241019056 0.8114521662542362 0.9583227285747226 0.88870348210096 0.8546600266534699 0.8811832701470536 0.7350576587134887 0.7570589948129053 1.0 16.96209153153398 -4.861912825562586 1.787759486798467 0.8567561837098948 0.7016043058447149 0.2242642041784082 0.07674273137782665 1.2604609844100243 4.735289158675923 0.02206737556235176 0.31797616987433763 1.3743178094142847e-05 4.861912825562586 -0.15515187786517992 DGKFS(ph)PIQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DGKFSPIQEK 10 1 O43683-2;O43683-3;O43683;A0A590UJ99 O43683-2 BUB1 Mitotic checkpoint serine/threonine-protein kinase BUB1 1 DGKFS(1)PIQEK 127.71 0.0014657 4228500.0 19465.0 24927.0 22340.0 25152.0 25450.0 25626.0 25987.0 27860.0 20525.0 22689.0 True False 22760.040048725772 27401.587823196092 22872.67032492181 23742.81498388422 20463.255194353653 24282.12744800525 23525.32323041282 27128.704520110026 20825.139295514902 26802.336093974816 0.8491812045384449 1.0223581902383496 0.8533834604836406 0.885848714852196 0.7634877468368814 0.9059705602850002 0.8777340582525316 1.0121768649191956 0.7769897080052066 1.0 14.71007113113965 DGKFS(ph)PIQEK ddPTM_PC-9_Lapatinib_30min_R1 1 DGKFSPIQEK 10 1 O43683-2;O43683-3;O43683;A0A590UJ99 O43683-2 BUB1 Mitotic checkpoint serine/threonine-protein kinase BUB1 1 DGKFS(1)PIQEK 53.946000000000005 0.045624 16008000.0 54208.0 57411.0 55940.0 51499.0 56968.0 50330.0 52346.0 49317.0 53615.0 42013.0 True False 53434.98397947028 57278.06835682131 51340.82913464455 55286.40825562786 53617.25424339728 48177.50322496037 55056.21974905493 51608.44786055998 47576.31410902057 49274.89107119639 1.0844262223180372 1.16241897468756 1.0419267910803318 1.1219996037281044 1.0881252718737964 0.9777292689566695 1.1173280864183992 1.0473579289296018 0.965528549627404 1.0 15.588565061549444 -7.0479841329269775 0.38689883096957745 0.9886463014355135 1.1267309702494017 0.3895171309549381 0.048658287652780526 1.495552193671343 0.5048922917231593 0.05376581460584151 0.07593442111970239 8.953974785547943e-08 7.0479841329269775 0.13808466881388826 DGKS(ph)PTVPCLQEEAGEPLGGK ddPTM_PC-9_AZD4547_30min_R2 3 DGKSPTVPCLQEEAGEPLGGK 21 1 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 DGKS(0.798)PT(0.202)VPCLQEEAGEPLGGK;DGKS(0.5)PT(0.5)VPCLQEEAGEPLGGK;DGKS(0.83)PT(0.17)VPCLQEEAGEPLGGK 97.346 0.00013758 59243900.0 130895.0 152265.0 170912.0 161654.0 167298.0 169764.0 142877.0 170539.0 143516.0 151072.0 True False 172516.88721486425 201481.68354563712 168645.59520808322 124387.16782940342 144071.5604736845 159148.6302432012 155592.77621057563 144186.11614635948 151101.96276627918 145783.0152627377 1.1833812526373213 1.382065552578374 1.1568260877588614 0.85323497806124 0.9882602593589609 1.0916815649365963 1.0672901498858305 0.9890460551011364 1.0364853717283553 1.0 17.153463119865755 -5.5263390292073025 23.82136923633722 1.0086281898562115 1.2794040470313104 0.696667422832313 0.07476274576282772 28.14938402160622 193785.81425748847 0.02040475975913916 0.03560440621050056 2.9761921769689997e-06 5.5263390292073025 0.2707758571750989 DGKS(ph)PTVPCLQEEAGEPLGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DGKSPTVPCLQEEAGEPLGGK 21 1 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 DGKS(0.573)PT(0.427)VPCLQEEAGEPLGGK;DGKS(0.659)PT(0.341)VPCLQEEAGEPLGGK 85.00200000000001 0.00021819 18977100.0 90596.0 103254.0 99567.0 117701.0 176429.0 184398.0 231520.0 201656.0 196207.0 163937.0 True False 105932.11344743671 113504.37473808655 101941.05488995017 111106.59456179073 141859.00395617384 174727.84426587351 209588.7495403538 196362.74367219373 199076.15618782473 193657.4803754221 0.5470075994073555 0.5861089100098189 0.5263987463449821 0.5737273579435238 0.7325253002423022 0.9022519756383702 1.0822651886931893 1.0139693199122866 1.0279807204033535 1.0 17.563147703621787 -6.683954503945409 1.7084198648563986 1.0337359004636577 0.5537481637428727 0.9814227712920557 0.02949356465815192 0.04272677321207113 0.2575711289940804 0.012139019714852994 0.011745425981885877 2.0703582251299398e-07 6.683954503945409 -0.479987736720785 DGKS(ph)PTVPCLQEEAGEPLGGK ddPTM_PC-9_Lapatinib_30min_R1 4 DGKSPTVPCLQEEAGEPLGGK 21 1 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 DGKS(0.903)PT(0.097)VPCLQEEAGEPLGGK;DGKS(0.581)PT(0.419)VPCLQEEAGEPLGGK;DGKS(0.534)PT(0.466)VPCLQEEAGEPLGGK;DGKS(0.74)PT(0.26)VPCLQEEAGEPLGGK 81.788 0.00033808 37622000.0 86942.7 133391.0 137762.0 123626.0 202828.0 244435.0 287724.0 297067.0 280599.0 266884.0 True False 85702.8811546617 133082.14133501862 126435.7401366982 132717.86844424665 190898.05581519066 233981.08485581525 302620.94087565556 310869.8173164014 248994.985781536 313014.54379942326 0.27379839963468056 0.42516280464046546 0.4039292826524924 0.42399904756275797 0.6098696038146915 0.7475086684973593 0.9667951437731666 0.9931481570888406 0.7954741743281092 1.0 18.255870166035088 -6.664399916590405 1.265569263288429 0.9460258662280289 0.3659615644789795 0.9311446381830264 0.06815645296834762 0.10379735577602696 0.34963371060095355 0.031674198031347904 0.031248044152644247 2.1657089106510858e-07 6.664399916590405 -0.5800643017490494 down DGKSPT(ph)VPCLQEEAGEPLGGK ddPTM_PC-9_Lapatinib_30min_R1 1 DGKSPTVPCLQEEAGEPLGGK 21 1 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 DGKS(0.234)PT(0.766)VPCLQEEAGEPLGGK 94.45 0.0005172999999999999 0.0 8264.7 14296.0 17209.0 14103.0 22024.0 28748.0 28260.0 29883.0 30794.0 25167.0 True False 8146.843862439646 14262.898490343623 15794.142448661029 15140.181666228846 20728.591620849973 27518.515054861124 29723.164522758027 31271.473273254935 27325.655444804237 29517.08241708041 0.2760043742577138 0.4832082754252916 0.5350848103985223 0.5129294776596145 0.7022574700287832 0.9322911616405966 1.0069817911799563 1.0594364589082599 0.9257573312527637 1.0 14.849262506421045 -6.4731202747503005 1.156056255251428 1.0172841095498577 0.41300699150560427 0.936003101102176 0.06637887185938161 0.11014666873863244 0.309209984644885 0.030847597357077667 0.03688176954549289 3.3641838780696396e-07 6.4731202747503005 -0.6042771180442534 down DGLAFNALIHR ddPTM_PC-9_AZD4547_30min_R2 2 DGLAFNALIHR 11 0 O43707;M0QZQ3;C9JY79;Q9H254-2;Q9H254-4;Q9H254 O43707 ACTN4;SPTBN4 Alpha-actinin-4;Spectrin beta chain, non-erythrocytic 4 0 ; 176.95 0.0019177 29104000.0 205028.0 199153.0 261070.0 345280.0 307060.0 265250.0 235550.0 287510.0 229130.0 262760.0 False True 270222.63915267424 263525.3126008224 257608.04121989204 265681.03052282275 264430.01924141205 248663.87556848975 256513.49367918668 243081.9358225382 241241.34402183397 253560.85237791904 1.0657111956301586 1.0392981019327536 1.0159614104622936 1.0477998793237973 1.0428661079246297 0.9806871732623355 1.0116447049044734 0.9586729715683295 0.9514139969141471 1.0 17.9519724973594 -6.974402917255885 1.2477292786156093 0.9706998174570398 1.0429265861703072 0.6699477441065783 0.021120766468026686 0.27122599074799414 0.867411080644368 0.011725495611923908 0.00868399256914324 1.0607110245715612e-07 6.974402917255885 0.07222676871326739 DGLAFNALIHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DGLAFNALIHR 11 0 O43707;M0QZQ3;C9JY79;Q9H254-2;Q9H254-4;Q9H254 O43707 ACTN4;SPTBN4 Alpha-actinin-4;Spectrin beta chain, non-erythrocytic 4 0 ; 176.95 0.0016471 28221000.0 169153.0 178205.0 206577.0 226258.0 245277.0 212594.0 229007.0 195411.0 181298.0 168296.0 False True 197787.26197596246 195896.0146841844 211502.57912763546 213581.49779833367 197216.7325856771 201445.19638965224 207313.79909289847 190281.66830506915 183949.14026788136 198806.732569597 0.9948720519649522 0.9853590577754019 1.0638602445397265 1.0743172277808268 0.9920022830043581 1.0132715013518547 1.0427906359776995 0.957118835190637 0.9252661511525301 1.0 17.601007088883804 -7.771905254571679 24.85139836039395 0.9558943298713638 1.0241626656084073 0.43241549292383663 0.032923916880184326 186.17729240460196 442073.4210255668 0.018532942000819282 0.009052790899965663 1.6908097574709922e-08 7.771905254571679 0.0682683357370435 DGLAFNALIHR ddPTM_PC-9_Lapatinib_30min_R1 2 DGLAFNALIHR 11 0 O43707;M0QZQ3;C9JY79;Q9H254-2;Q9H254-4;Q9H254 O43707 ACTN4;SPTBN4 Alpha-actinin-4;Spectrin beta chain, non-erythrocytic 4 0 ; 176.95 0.0019177 33729000.0 164009.0 165937.0 167740.0 154366.0 164384.0 165284.0 160050.0 147872.0 173161.0 143863.0 False True 161670.20158443294 165552.78307163875 153949.06469512507 165718.5905898802 154715.2563113785 158215.18861582238 168336.60586933538 154742.67295327614 153657.78471383208 168729.52786460205 0.9581618797284024 0.9811725615950725 0.9124014429689056 0.9821552438815688 0.9169423886228771 0.937685244652513 0.9976712908508701 0.9171048773244376 0.9106751299460497 1.0 17.364352943474934 -5.21073755964257 24.99726711787574 0.9455522705884922 0.9696672206479029 0.06782119373061901 0.03360139262423303 979.6524568191654 482989.988791817 0.00822957908177033 0.021773352511151853 6.155487310582719e-06 5.21073755964257 0.024114950059410667 DGLAPEKTS(ph)PDRDK ddPTM_PC-9_Lapatinib_30min_R1 1 DGLAPEKTSPDRDK 14 2 Q7L4I2;E9PI52 Q7L4I2 RSRC2 Arginine/serine-rich coiled-coil protein 2 1 DGLAPEKT(0.225)S(0.775)PDRDK 79.514 0.035663 74857000.0 105150.0 191370.0 159110.0 178910.0 194870.0 192460.0 199280.0 201340.0 145400.0 155650.0 True False 103650.54171785168 190926.8945227379 146028.58998236156 192067.63822626407 183408.12972916072 184228.9344461729 209597.7433154712 210694.9914278072 129023.52087012203 182553.895109412 0.5677804993190075 1.0458659039200868 0.7999204284019285 1.0521147089803267 1.004679355755388 1.0091755880407645 1.1481417210509297 1.1541522644670446 0.7067694764485467 1.0 17.4779629259819 -4.757535838790694 24.95755065296247 0.9978325903447032 0.5677798664713991 0.4771901392378527 0.13279670899223148 97.02812760310198 620267.0894956933 0.03256619506596949 0.23973611741806972 1.747689033908426e-05 4.757535838790694 -0.43005272387330407 DGLGFCALIHR ddPTM_PC-9_AZD4547_30min_R2 2 DGLGFCALIHR 11 0 P12814-4;P12814-3;P12814;P12814-2;H9KV75;G3V2N5;G3V2W4;G3V2X9 P12814-4 ACTN1 Alpha-actinin-1 0 ; 145.46 0.00017123 5786100.0 84808.0 77446.0 94193.0 134189.0 120537.0 101910.0 85482.0 116449.0 84573.0 104797.0 False True 111775.17988401579 102478.90496092608 92943.93927538705 103253.79924938334 103802.51817007118 95537.55158976367 93089.73239942346 98454.48278181213 89043.35612079847 101128.08892772412 1.105283221201788 1.0133574761228543 0.9190714494942522 1.0210199791590886 1.0264459584938708 0.9447182538774564 0.9205131174381666 0.9735621806536578 0.8805007299647226 1.0 16.62582424446066 -6.772394754336862 21.556561158339658 0.9407472519205601 1.0116101682276355 0.3340991859750292 0.05127601348930363 51.56922920473583 101468.46057263055 0.01817556855938569 0.016237612227721562 1.6889050942527154e-07 6.772394754336862 0.07086291630707542 DGLGFCALIHR ddPTM_PC-9_Lapatinib_30min_R1 1 DGLGFCALIHR 11 0 P12814-4;P12814-3;P12814;P12814-2;H9KV75;G3V2N5;G3V2W4;G3V2X9 P12814-4 ACTN1 Alpha-actinin-1 0 121.9 0.0006062999999999999 2910000.0 27955.0 26418.0 28751.0 27047.0 28992.0 25318.0 26761.0 24173.0 29780.0 21929.0 False True 27556.356573680867 26356.83074411709 26387.203762069465 29036.12660614706 27286.747560465064 24235.208159140595 28146.55363742136 25296.16582787511 26425.862802697608 25719.398431444202 1.0714230601906622 1.024784106610113 1.0259650447270499 1.1289582329673726 1.0609403494875154 0.9422929631787555 1.0943706056129894 0.9835442261724265 1.0274681530027425 1.0 14.650569278431412 -6.586994942414691 24.999968025239106 1.0124540875544976 1.0621298042229859 0.2568607771655552 0.044837708122555 94.51736619907363 36852.77084121846 0.014597825826225222 0.014597826248837925 2.5882430564152596e-07 6.586994942414691 0.049675716668488246 DGLILTSR ddPTM_PC-9_AZD4547_30min_R2 1 DGLILTSR 8 0 Q99497;K7ELW0;K7EN27 Q99497 PARK7 Protein deglycase DJ-1 0 143.89 0.0077832 4367900.0 12906.0 10939.0 13722.0 23024.0 17545.0 14865.0 12910.0 15198.0 12277.0 15635.0 False True 17009.83953852357 14474.817826195926 13540.037314204483 17716.172517254025 15109.179598744757 13935.489200096546 14058.964990016095 12849.498315296642 12925.937156007754 15087.623408923624 1.1274035066691184 0.9593835578925404 0.8974267813575055 1.1742188969785485 1.0014287332893252 0.9236371310709118 0.9318210435780677 0.8516582079916419 0.8567245354468926 1.0 13.881077951074168 -6.761875809655189 3.521314358032807 0.9019245233389223 1.0303948332724084 0.34552195659681206 0.08255573521963738 0.2773618950324108 7.291074521137841 0.030248611099712556 0.028200892454403464 1.7303110862212188e-07 6.761875809655189 0.12847030993348618 DGLILTSR ddPTM_PC-9_Lapatinib_30min_R1 2 DGLILTSR 8 0 Q99497;K7ELW0;K7EN27 Q99497 PARK7 Protein deglycase DJ-1 0 ; 131.03 0.017187 15636400.0 66688.0 65000.0 57938.0 53572.0 63276.0 67283.0 58966.0 49151.0 64697.0 56863.0 False True 65737.01689091863 64849.496493588085 53174.56128714762 57511.863590953144 59554.23008540244 64405.46293433349 62018.97095714615 51434.734894547175 57410.14257038711 66691.69378481522 0.9856852204567348 0.9723774103388183 0.7973191003173282 0.8623542202499558 0.8929782212093423 0.9657194064097638 0.929935460287665 0.7712314978909436 0.8608289775279123 1.0 16.02521946957002 DGLLPENTFIVGYAR ddPTM_PC-9_AZD4547_30min_R2 1 DGLLPENTFIVGYAR 15 0 P11413;P11413-2;P11413-3;E7EUI8;E7EM57;E9PD92 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 131.13 4.7794e-05 4672200.0 8328.3 6768.4 10385.0 13768.0 11931.0 9847.8 11477.0 10075.0 10093.0 12738.0 False True 10976.526160598623 8956.15293672406 10247.288114561545 10594.000313479566 10274.58659405093 9232.015509230458 12498.430766104946 8518.14025046807 10626.49537473212 12292.04649714545 0.8929779238264087 0.7286136558956171 0.8336519160532989 0.8618581385890286 0.8358727406731639 0.75105601914005 1.0167900657557247 0.6929798266257955 0.8645017228986145 1.0 13.5854375088883 -11.546827122717461 1.538263903723099 1.1871015420049649 0.8281088634635229 0.25125766217177103 0.0874408466661205 143704.99429145994 34782.0686049807 94877.83177920002 0.022595387862913405 2.839048928568546e-12 11.546827122717461 -0.358992678541442 DGLLPENTFIVGYAR ddPTM_PC-9_Lapatinib_30min_R1 2 DGLLPENTFIVGYAR 15 0 P11413;P11413-2;P11413-3;E7EUI8;E7EM57;E9PD92 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ; 147.52 0.00056707 41366000.0 84396.0 69735.0 85161.0 67884.0 85450.0 90911.0 81133.0 72334.0 80174.0 81305.0 False True 83192.49756366915 69573.53289200566 78159.39131096654 72876.41581438566 80423.99900116376 87022.94845389183 85333.66975318217 75694.9017082495 71143.9598503518 95358.46091789755 0.8724186271766368 0.729599997968797 0.8196377181282404 0.7642364936775914 0.8433860847482408 0.9125875943909949 0.8948725569999856 0.7937932405748649 0.7460686672743793 1.0 16.54107333049177 -6.429526179041444 6.09115974483206 0.8602129432087797 0.7938354112245679 0.17761412773083096 0.07265526238536164 0.4599543465254448 24.634444480293386 0.022758225475757024 0.025729789256335574 3.7194080009168176e-07 6.429526179041444 -0.06637753198421181 DGLNDDDFEPYLS(ph)PQAR ddPTM_PC-9_AZD4547_30min_R2 3 DGLNDDDFEPYLSPQAR 17 0 Q9Y5A9;S4R3J8 Q9Y5A9 YTHDF2 YTH domain-containing family protein 2 1 DGLNDDDFEPYLS(1)PQAR;DGLNDDDFEPYLS(1)PQAR;DGLNDDDFEPYLS(1)PQAR 205.92 2.7742e-17 28376000.0 28833.7 31843.8 37474.9 29237.0 30422.100000000002 40432.3 36362.5 37756.4 37569.6 29729.8 True False 38002.216821782626 42136.68561055105 36977.95834033534 22496.861357147143 26198.516538670443 37904.06188934164 39598.6920565035 31922.01593575906 39555.45235614146 28688.968751046843 1.3246281925137497 1.4687417305306072 1.288926021050723 0.7841641695931035 0.9131912954422412 1.3212068449814371 1.380275896290576 1.1126930428474968 1.3787687072125276 1.0 14.808208489709354 -3.7359955564936342 0.01654773416690437 3.9965923971786695e-07 2.5471379708030337 0.059934220691682194 0.21187641709805058 12782.96047694225 24.98199727868113 1634.6614844127644 2251.5148577824784 0.0001836557134081151 3.7359955564936342 2.547137571143794 DGLNDDDFEPYLS(ph)PQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DGLNDDDFEPYLSPQAR 17 0 Q9Y5A9;S4R3J8 Q9Y5A9 YTHDF2 YTH domain-containing family protein 2 1 DGLNDDDFEPYLS(1)PQAR;DGLNDDDFEPYLS(1)PQAR;DGLNDDDFEPYLS(1)PQAR;DGLNDDDFEPYLS(1)PQAR 167.9 2.0172e-05 22754000.0 40075.2 51651.399999999994 47795.9 41845.5 51576.5 49478.9 65408.0 41476.200000000004 46921.0 37335.7 True False 46859.139838720504 56779.009639789394 48935.53552296017 39501.03229994145 41470.45507000317 46884.139381374676 59212.080727088214 40387.493697666476 47607.13085918906 44104.36686076141 1.0624603225040274 1.2873784090142855 1.109539463007164 0.8956263316203404 0.9402800226319183 1.0630271494291954 1.3425446263410206 0.9157255068454061 1.0794198907669612 1.0 15.428633886499236 -5.523051521642018 24.999999834189186 1.0375620612521446 1.1808042745490768 0.16354022080356911 0.12909022099210335 10.129021644074642 1465586.3720201328 0.03619206524407503 0.06346763944431587 2.998806740549816e-06 5.523051521642018 0.1432422132969322 DGLNDDDFEPYLS(ph)PQAR ddPTM_PC-9_Lapatinib_30min_R1 4 DGLNDDDFEPYLSPQAR 17 0 Q9Y5A9;S4R3J8 Q9Y5A9 YTHDF2 YTH domain-containing family protein 2 1 DGLNDDDFEPYLS(1)PQAR;DGLNDDDFEPY(0.008)LS(0.992)PQAR;DGLNDDDFEPYLS(1)PQAR;DGLNDDDFEPYLS(1)PQAR 145.05 4.4987e-09 21982800.0 18468.8 35615.9 38037.6 33509.6 44733.1 45786.7 50199.899999999994 47584.3 45005.399999999994 44285.5 True False 18205.431525236872 35533.433571784386 34910.29535738213 35974.00776874866 42101.987006658404 43828.509575010765 52799.005192002835 49795.240293027666 39936.41792412785 51940.189668280465 0.35050760579634177 0.6841221373799569 0.6721249109858684 0.6926044744637841 0.8105859311555386 0.8438265215226303 1.0165347013402772 0.9587034743432462 0.7688924160497773 1.0 15.664563661817368 -4.625549871168712 0.43132747056757936 0.9500326578296193 7.407541034737317e-20 0.7913422163773717 0.08598679636717702 2.826586251269854 0.3719251097858159 0.06601514709878013 1.4230609034095538 2.3683731496988372e-05 4.625549871168712 -0.9500326578296193 down DGLNQTTIPVS(ph)PPSTTKPSR ddPTM_PC-9_AZD4547_30min_R2 4 DGLNQTTIPVSPPSTTKPSR 20 1 Q71RC2-5;Q71RC2-3;Q71RC2;Q71RC2-4;X6RLN4;Q71RC2-2;Q71RC2-6 Q71RC2-5 LARP4 La-related protein 4 1 DGLNQTTIPVS(0.929)PPS(0.023)T(0.023)T(0.023)KPS(0.003)R;DGLNQTTIPVS(0.947)PPS(0.008)T(0.02)T(0.02)KPS(0.005)R;DGLNQTTIPVS(0.964)PPS(0.011)T(0.011)T(0.011)KPS(0.003)R;DGLNQTTIPVS(0.964)PPS(0.01)T(0.01)T(0.014)KPS(0.003)R 105.32 6.8475e-05 773998000.0 105270.0 93853.0 114112.0 122820.0 123584.0 116009.0 98989.0 130672.0 107685.0 113998.0 True False 138743.67024797562 124189.146854554 112598.80032054368 94505.74655008418 106426.49481511967 108754.93889095196 107798.82923289709 110479.64494383759 113377.0092567155 110006.96471829095 1.2612262378411627 1.1289207658131573 1.0235606500814742 0.8590887567173338 0.9674523343831888 0.9886186676403151 0.979927311956579 1.0042968209036318 1.0306348288679235 1.0 16.74723534042726 -5.042231261997285 2.092451183666297 0.9752200404987058 1.271122833027094 0.806831189295841 0.04436203529218184 0.1838957318193164 1.302275696638363 0.013055821865974595 0.08431359611790344 9.07337244044206e-06 5.042231261997285 0.29590279252838825 DGLNQTTIPVS(ph)PPSTTKPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DGLNQTTIPVSPPSTTKPSR 20 1 Q71RC2-5;Q71RC2-3;Q71RC2;Q71RC2-4;X6RLN4;Q71RC2-2;Q71RC2-6 Q71RC2-5 LARP4 La-related protein 4 1 DGLNQTTIPVS(0.99)PPS(0.003)T(0.003)T(0.003)KPS(0.001)R;DGLNQTTIPVS(0.998)PPS(0.001)T(0.001)T(0.001)KPSR;DGLNQTTIPVS(0.987)PPS(0.003)T(0.003)T(0.004)KPS(0.004)R;DGLNQT(0.001)T(0.001)IPVS(0.959)PPS(0.013)T(0.013)T(0.013)KPS(0.002)R;DGLNQTTIPVS(0.995)PPS(0.002)T(0.002)T(0.001)KPSR;DGLNQTTIPVS(0.999)PPSTTKPSR 119.69 6.0197e-06 637707000.0 180197.0 221260.0 202702.0 229136.0 245566.0 205888.0 226493.0 215332.0 202407.0 165048.0 True False 210700.79304701957 243225.2305436023 207535.1844316156 216298.25278893538 197449.1051102804 195090.87083489058 205037.9433726826 209679.76316311312 205366.81945857656 194969.895880751 1.0806837234805216 1.2475014639817297 1.0644473265685586 1.109393077386826 1.012715856559957 1.000620480169993 1.051638984810709 1.0754468643269888 1.0533257892499703 1.0 17.572891857815073 -5.694107909475365 1.7813644477169333 1.0381254587316762 1.1600861944534544 0.4539576203894883 0.05057419485654075 0.3030224518161717 1.9428261359905101 0.015037706713232707 0.03380873262458496 2.022516580030076e-06 5.694107909475365 0.12196073572177824 DGLNQTTIPVS(ph)PPSTTKPSR ddPTM_PC-9_Lapatinib_30min_R1 5 DGLNQTTIPVSPPSTTKPSR 20 1 Q71RC2-5;Q71RC2-3;Q71RC2;Q71RC2-4;X6RLN4;Q71RC2-2;Q71RC2-6 Q71RC2-5 LARP4 La-related protein 4 1 DGLNQTTIPVS(0.99)PPS(0.001)T(0.001)T(0.001)KPS(0.006)R;DGLNQTTIPVS(0.993)PPS(0.002)T(0.002)T(0.002)KPS(0.001)R;DGLNQTTIPVS(1)PPSTTKPSR;DGLNQTTIPVS(0.998)PPSTTKPSR;DGLNQTTIPVS(0.996)PPS(0.004)TTKPSR 129.74 3.1645e-06 654706000.0 187263.0 221815.0 235792.0 210187.0 260109.0 223251.0 214762.0 205116.0 248634.0 227119.0 True False 184592.59528017175 221301.40099577274 216406.0919434412 225644.85314327787 244809.90001396963 213703.0751534992 225881.32552146347 214646.43817277218 220630.22068790876 266376.216532955 0.692977014550151 0.8307851349348759 0.8124077095173708 0.8470908404668402 0.919038130356817 0.8022603441665023 0.847978578798976 0.805801812813934 0.828265464385456 1.0 18.023105751208952 -14.522878745280336 0.20731492203436083 1.8046785715970128 0.7996063759321751 0.5275622383902512 0.0519552228219582 125.64821898264701 1.2469732699643001 42.194880250174265 0.1176671896329423 3.0000000000000132e-15 14.522878745280336 -1.0050721956648379 DGLPRT(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 1 DGLPRTPSR 9 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 DGLPRT(0.995)PS(0.005)R 66.568 0.034668 31587000.0 45395.0 84337.0 85552.0 71168.0 83509.0 73229.0 79498.0 89063.0 86228.0 54289.0 True False 44747.65897557658 84141.72285814994 78518.24480027021 76401.93212948854 78597.16480501101 70097.16637513656 83614.01745329866 93201.19212046645 76516.09461890563 63672.78131445455 0.7027753154772003 1.3214708250705653 1.2331524268195515 1.199915105831011 1.2343918890059296 1.1008968813370115 1.3131830544728722 1.4637524888410767 1.2017080617387053 1.0 15.958389164046553 -4.756297028435941 24.999876515569312 1.2422095153260315 0.7027744795404943 0.6354943513523936 0.1194185904651648 101.12927424171453 491591.9455429797 0.02939950960591915 0.2413245399377035 1.7526813747603255e-05 4.756297028435941 -0.5394350357855372 DGMDNQGGYGS(ph)VGR ddPTM_PC-9_AZD4547_30min_R2 1 DGMDNQGGYGSVGR 14 0 P31942;P31942-2;P31942-3;P31942-4 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 1 DGMDNQGGYGS(1)VGR 87.824 0.005246100000000001 6601300.0 28307.0 36186.0 49178.0 67356.0 60540.0 53752.0 42948.0 54491.0 47634.0 61263.0 True False 37308.03717782324 47882.41684420205 48525.86758766563 51828.114839826405 52135.06599646665 50390.87894272379 46770.28879869955 46070.66802861095 50151.83599326166 59118.20101700596 0.6310753124421224 0.8099437401761969 0.820827879618777 0.8766862649443192 0.881878424911297 0.8523750397653057 0.7911318002597135 0.7792975299664184 0.8483315650764638 1.0 15.851314748097572 -14.522878745263323 0.023371208553280617 2.073883307686677 9.874007194961493e-09 0.47460667174674287 0.06431886352760856 2690.482850828739 4.734967827780272 297.82168956464363 146.88409534061597 3.0000000001175295e-15 14.522878745263323 -2.0738832978126696 DGMDNQGGYGS(ph)VGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DGMDNQGGYGSVGR 14 0 P31942;P31942-2;P31942-3;P31942-4 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 1 DGMDNQGGYGS(1)VGR;DGMDNQGGYGS(1)VGR 75.998 0.014813 10835500.0 45067.0 45871.0 70723.0 77219.0 110058.0 90838.0 81311.0 97020.0 91306.0 71996.0 True False 52695.952986176424 50424.76972912215 72409.30453847106 72892.6697773759 88492.92495796362 86074.29536884029 73608.63343933878 94473.32780118738 92641.1775160187 85048.30487997738 0.61960027375669 0.5928956467772407 0.8513903321254569 0.8570737521487833 1.0405019251453322 1.0120636206719325 0.8654920699856088 1.1108196446068015 1.0892771777962722 1.0 16.375994860992236 -5.504529407629679 1.0440678822568725 1.0228203959636637 0.5451839656796855 0.8291607478304923 0.07167981022506655 0.2936545067687414 0.528579947146181 0.026643774067249725 0.12035811480457903 3.1294685569016883e-06 5.504529407629679 -0.4776364302839782 DGMDNQGGYGS(ph)VGR ddPTM_PC-9_Lapatinib_30min_R1 2 DGMDNQGGYGSVGR 14 0 P31942;P31942-2;P31942-3;P31942-4 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 1 DGMDNQGGY(0.003)GS(0.997)VGR;DGMDNQGGYGS(1)VGR 91.59200000000001 0.0044784 10809500.0 39486.3 35340.0 37735.9 33674.3 41362.4 33130.2 36206.9 37616.2 44562.6 33822.0 True False 38923.21812109942 35258.17240128314 34633.39996678645 36150.82035617175 38929.54495360724 31713.29857626828 38081.51612027767 39363.985976689495 39543.490723018556 39668.08763501786 0.9812224496231855 0.8888296488020822 0.8730796474346061 0.9113325726410576 0.981381943888854 0.7994662830247627 0.9600038315600673 0.9923338462613481 0.9968590138968708 1.0 15.275691227600362 -7.513149720195168 24.19181829179467 0.9919916645894941 0.9050013154481401 0.4104060506009465 0.049183174856173566 309.5396208479559 769697.5834804986 0.021488758309171106 0.013345467940935269 3.067964145394206e-08 7.513149720195168 -0.08699034914135395 DGMDNQGGYGSVGR ddPTM_PC-9_Lapatinib_30min_R1 2 DGMDNQGGYGSVGR 14 0 P31942;P31942-2;P31942-3;P31942-4 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 0 ; 159.66 0.00087133 9334400.0 25520.0 26018.0 23564.0 25417.5 25328.0 23789.0 19578.6 19147.6 22688.0 22712.9 False True 25156.080120205155 25957.756919541152 21626.65887967045 27286.787740294407 23838.2568367639 22771.59992486752 20592.284109174456 20037.267397750442 20132.638524768416 26638.79450196312 0.944340034544405 0.9744343693040698 0.8118482567999349 1.0243251712566623 0.8948699549826538 0.8548284691782653 0.7730186179279595 0.7521837144797906 0.7557638737475437 1.0 14.701241176470987 -6.840579681702569 2.5681401820749907 0.8009226314859956 0.9337469139112732 0.27111799600628994 0.08407665739755575 0.31709629948644447 4.262721829101363 0.03124405205376325 0.027591192312375074 1.443511733264871e-07 6.840579681702569 0.13282428242527755 DGPEPPS(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 2 DGPEPPSPAK 10 0 Q9H4Z2-2;Q9H4Z2 Q9H4Z2-2 ZNF335 Zinc finger protein 335 1 DGPEPPS(1)PAK;DGPEPPS(1)PAK 103.46 0.0028212 22438000.0 165934.0 148076.0 157787.0 178207.0 193710.0 196640.0 186650.0 186774.0 172227.0 192349.0 True False 218697.560358389 195938.67121599682 155694.64128380571 137124.12942070406 166816.7101779903 184344.06971456346 203261.48841103853 157912.36993954546 181330.56761161084 185614.92005647862 1.1782326565765513 1.0556191881362602 0.8388045596573336 0.7387559651938548 0.8987246829469935 0.9931532963970329 1.095070850711734 0.8507525682283307 0.9769180600160583 1.0 17.501953155949472 -5.008294640834047 3.9860340645961734 0.9201557667123239 1.1635963899893822 0.42087655435587934 0.09543129338239956 0.20786115851901943 7.543118138195029 0.026787466189637947 0.10560440028632023 9.81082116158666e-06 5.008294640834047 0.2434406232770583 DGPS(ph)SAPATPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DGPSSAPATPTK 12 0 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 DGPS(0.728)S(0.272)APATPTK 84.169 0.010355 3365700.0 28050.0 33380.0 30900.0 37315.0 36750.0 31292.0 32267.0 27235.0 24920.0 22713.0 True False 32798.31098724672 36693.74579926525 31636.77318890259 35224.36152686228 29549.101312082388 29650.99243358232 29210.43616715014 26520.110107867793 25284.407855991794 26830.68710399092 1.2224178553507168 1.367603656851831 1.1791264631533342 1.312838593746742 1.101317353430249 1.1051149125872328 1.0886950473514054 0.9884245604699057 0.9423690029999595 1.0 14.711596380432914 -6.7904405890845565 0.7385056409000177 0.9680763389202373 1.2933324816007292 0.7971608988085432 0.05977139567614767 0.27940793458441704 0.33297283057856036 0.041161981562182814 0.03966293684674069 1.620165615275463e-07 6.7904405890845565 0.32525614268049197 DGPSS(ph)APATPTK ddPTM_PC-9_AZD4547_30min_R2 1 DGPSSAPATPTK 12 0 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 DGPS(0.005)S(0.995)APATPTK 153.49 0.00021840000000000002 3747400.0 29942.0 27086.0 37176.0 36332.0 37461.0 37316.0 30302.0 38890.0 36884.0 36618.0 True False 39462.933167710566 35841.01980440104 36683.02194963312 27956.21872380443 32260.18677392859 34982.62462097563 32998.8192972477 32880.44410329557 38833.61293982159 35336.014965651746 1.1167907078959067 1.0142915051185082 1.0381199460462853 0.7911536926554729 0.9129548650374695 0.989999145488827 0.933857972647003 0.9305079855568574 1.0989811097139752 1.0 15.108851728056312 -5.029507745579553 1.79862408273781 0.9496633786687605 1.1208176581159193 0.27142095875430017 0.07757029778355128 0.7055777647628476 3.3428756385321403 0.02212374616938327 0.17502449888262195 9.343127047761553e-06 5.029507745579553 0.17115427944715877 DGPSS(ph)APATPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DGPSSAPATPTK 12 0 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 DGPS(0.177)S(0.823)APATPTK;DGPS(0.053)S(0.946)APATPTK 97.463 0.0039631 9599800.0 79605.0 91345.0 82439.0 97419.0 96777.0 83381.0 93014.0 68609.0 72835.0 66681.0 True False 93080.55422958183 100413.12792192573 84404.65841164862 91960.92926665948 77814.24156950736 79008.35357613847 84203.04055695602 66808.08644724432 73900.07408471775 78769.73745349456 1.1816791224489778 1.2747678381079963 1.0715366223161644 1.1674652250929867 0.9878697591882756 1.0030292867585702 1.0689770371098326 0.848144079275212 0.9381784994313096 1.0 16.265353846648736 -6.043523650114786 0.6605476579976168 0.9395991954046402 1.2508868841895402 0.6760268346790288 0.06833196706467597 0.5516779695465797 0.4715773801780579 0.04117898853681684 0.10361794147275807 9.046411728935833e-07 6.043523650114786 0.3112876887849 DGPSS(ph)APATPTK ddPTM_PC-9_Lapatinib_30min_R1 2 DGPSSAPATPTK 12 0 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 DGPS(0.004)S(0.996)APATPTK;DGPS(0.24)S(0.741)APAT(0.019)PTK 130.56 0.00014222 11691300.0 79292.0 127654.0 120435.0 120724.0 134642.0 130034.0 110484.0 113570.0 128814.0 102567.0 True False 78161.2815396282 127358.42500603863 110533.29919254397 129602.4456834582 126722.6222763567 124472.74894405925 116204.32091763617 118846.87680766871 114305.61084844502 120295.56928806343 0.6497436439446976 1.0587125175081242 0.9188476337632816 1.0773667430186746 1.0534271796237387 1.034724301823561 0.9659900327614708 0.9879572249504416 0.9502063253445796 1.0 16.876223980759157 -4.756217536219113 24.999709271124143 1.0056252898524758 0.649743090198418 0.8280882705127445 0.048593491986886145 64.90436338911454 310697.1820085698 0.012186789684190558 0.10089762026430513 1.7530022107029166e-05 4.756217536219113 -0.35588219965405776 DGPSSAPATPT(ph)KAPYSPTTSK ddPTM_PC-9_AZD4547_30min_R2 1 DGPSSAPATPTKAPYSPTTSK 21 1 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 DGPSS(0.001)APAT(0.013)PT(0.619)KAPY(0.129)S(0.184)PT(0.037)T(0.012)S(0.004)K 90.755 0.00030202 7524000.0 39162.0 19312.0 52051.0 95671.0 82997.0 47944.0 41429.0 50353.0 42861.0 62334.0 True False 51614.70137979697 25554.226333256785 51360.76973048075 73615.52905221556 71474.29918250322 44946.054100869704 45116.100741392496 42572.10084683064 45126.544957534235 60151.70563299295 0.8580754416959796 0.4248296214436919 0.8538539213476533 1.2238311163006783 1.1882339566328088 0.7472116314556672 0.7500385943610968 0.7077455310507442 0.7502122256161349 1.0 15.876318025901305 -10.49735676186219 17.65313148964433 0.9999999999999971 0.8355247204003332 0.048870307001902424 0.21986665135654954 0.0 0.0 0.2369342568962052 0.05746499808884022 3.181582858600419e-11 10.49735676186219 -0.1644752795996639 DGPSSAPATPT(ph)KAPYSPTTSK ddPTM_PC-9_Lapatinib_30min_R1 1 DGPSSAPATPTKAPYSPTTSK 21 1 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 DGPSSAPAT(0.03)PT(0.538)KAPY(0.047)S(0.11)PT(0.186)T(0.065)S(0.023)K 91.926 0.00029565 8639200.0 95134.0 32740.0 45931.0 41032.0 37516.0 41580.0 24141.0 25507.0 49606.0 33914.0 True False 93777.37171456113 32664.192541539614 42154.73047878727 44049.63015873941 35309.38263929388 39801.720327714116 25390.902857179804 26692.148337881543 44018.84990566211 39775.989712435556 2.357637670175749 0.8212037658318151 1.0598034337686895 1.1074427180115582 0.8877059475971949 1.0006468881218187 0.6383474815019272 0.6710618272695429 1.1066688779814338 1.0 15.279610207917425 -4.759206414907123 24.99982753099944 0.9138640286125794 2.3576395325111066 0.8791869976658092 0.1596959927573744 19.776515019471606 221362.65314234936 0.0419282706105926 0.27111210018930443 1.7409792103859418e-05 4.759206414907123 1.4437755038985272 DGPSSAPATPTKAPY(ph)SPTTSK ddPTM_PC-9_Lapatinib_30min_R1 1 DGPSSAPATPTKAPYSPTTSK 21 1 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 DGPSSAPAT(0.003)PT(0.062)KAPY(0.606)S(0.17)PT(0.106)T(0.039)S(0.015)K 80.541 0.0040103000000000005 7005000.0 54472.0 21776.0 27416.0 24357.0 23636.0 22712.0 19091.0 21983.0 34548.0 24765.0 True False 53695.219291058624 21725.579009913443 25161.962308820435 26148.29503257009 22245.77695016393 21740.660704257883 20079.438567019584 23004.41043288703 30656.840433431753 29045.597252711734 1.8486526141598127 0.7479818308051873 0.8662917856327187 0.9002498659286082 0.7658915310507872 0.7485010728167467 0.6913074774231038 0.792010239374207 1.0554728885999958 1.0 14.826031875259769 -4.7587428519795045 24.9999062147089 0.8271053317763393 1.8486539740628667 0.8796836269070766 0.11170907251500119 22.909378241265856 212355.0057569594 0.02772286826720563 0.18543979862209456 1.7428385116855144e-05 4.7587428519795045 1.0215486422865274 DGPSSAPATPTKAPYS(ph)PTTSK ddPTM_PC-9_AZD4547_30min_R2 1 DGPSSAPATPTKAPYSPTTSK 21 1 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 DGPSSAPATPTKAPY(0.358)S(0.466)PT(0.129)T(0.036)S(0.01)K 109.28 2.2028000000000003e-05 6791900.0 21711.0 11221.0 22003.0 53903.0 39595.0 28284.0 20451.0 27491.0 24400.0 36140.0 True False 28614.646383146224 14847.968811385375 21711.225843495187 41476.49614304827 34097.917709449895 26515.397008781067 22271.099381163393 23242.897630334257 25689.734186412712 34874.749600159856 0.8204975436731182 0.425751266507081 0.6225485800590714 1.1892987510613742 0.9777250905134413 0.760303581037311 0.6386024168345945 0.6664677996778425 0.7366284914141709 1.0 15.089895238013726 -5.560795684679352 24.99995618568105 0.8370010152599346 0.5983793128003525 0.24421021957631206 0.18276304368619387 230.90922722583267 152245.46966963785 0.05333982198007082 0.09238750863616244 2.7491872134198937e-06 5.560795684679352 -0.23862170245958214 DGPSSAPATPTKAPYS(ph)PTTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DGPSSAPATPTKAPYSPTTSK 21 1 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 DGPSSAPATPT(0.003)KAPY(0.082)S(0.828)PT(0.059)T(0.021)S(0.007)K;DGPS(0.001)S(0.002)APAT(0.044)PT(0.065)KAPY(0.271)S(0.533)PT(0.072)T(0.008)S(0.003)K 96.561 0.00014861 9858700.0 24747.6 11064.6 15255.0 28877.0 38642.0 53732.0 30782.0 53382.0 50546.0 37745.0 True False 28936.87989261987 12163.020364606062 15618.737054909661 27259.11531049717 31070.377493918022 50914.199330220006 27866.106117619107 51980.77906290427 51285.139626362834 44587.86971074437 0.6489854769995196 0.27278765376124553 0.35029117013737937 0.6113572029194416 0.6968347601148339 1.1418845452926218 0.624970564828402 1.1658053950574458 1.1502038549736906 1.0 15.444363652734301 -6.386692491407033 1.5124447635056406 1.0134768083145664 0.41151059159027564 0.6744576363822526 0.17878334927333978 0.2319913310311762 1.0674860425097459 0.06909895015782953 0.08528679563313095 4.104946568859425e-07 6.386692491407033 -0.6019662167242907 DGQAMLWDLNEGK ddPTM_PC-9_Lapatinib_30min_R1 3 DGQAMLWDLNEGK 13 0 D6R9L0;P63244;D6R9Z1;D6RFX4;H0Y8W2;J3KPE3;H0YAM7;H0YAF8;D6RAC2;D6REE5;H0Y8R5 D6R9L0 GNB2L1 Guanine nucleotide-binding protein subunit beta-2-like 1;Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed 0 ;; 178.15 0.00059063 11734000.0 57333.0 60879.0 59073.0 55898.0 58836.0 56363.0 50381.0 51479.0 51908.0 48068.0 False True 56515.42090641548 60738.03841589461 54216.24596837428 60008.92539026169 55375.382156026564 53952.48587857029 52989.48166387375 53870.90227332901 46061.574424527425 56376.489753416026 1.002464345573964 1.077364672429154 0.9616818323650445 1.064431745444484 0.9822424630946661 0.957003284783284 0.9399216215064712 0.9555561637298429 0.8170351617490766 1.0 15.782806031757255 -6.8449896544265005 1.225119808838638 0.9187163580314728 1.0274744146977126 0.40853217365780503 0.0527051532448398 0.4266001435073183 1.341163492372689 0.026203422059758206 0.02184139212729611 1.428927997404439e-07 6.8449896544265005 0.10875805666623983 DGQDAIAQS(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 4 DGQDAIAQSPEK 12 0 Q9NWH9;H7BXE3;H0YL55 Q9NWH9 SLTM SAFB-like transcription modulator 1 DGQDAIAQS(1)PEK;DGQDAIAQS(1)PEK;DGQDAIAQS(1)PEK;DGQDAIAQS(1)PEK 162.7 0.00069425 204130600.0 204683.0 267919.0 204344.0 161747.0 161284.0 226280.0 253308.0 249901.0 220511.0 204866.0 True False 269767.9363291202 354518.57730840007 201634.2650440021 124458.72811623888 138892.50056448817 212130.6758289844 275851.92127738165 211284.54260369448 232166.76127787132 197693.70369635697 1.3645752559902664 1.7932719691109364 1.019932659836742 0.629553323091151 0.702564107847445 1.0730269698159003 1.3953500598130832 1.0687469487051142 1.1743761027132278 1.0 17.592907398155972 -5.277275972884241 23.396876305323385 1.0021389153441196 1.5789235363180774 0.5033015420752107 0.22683014790188263 265.2182892739668 391832.3397366227 0.0659535283200596 0.1381951596382409 5.281095573554112e-06 5.277275972884241 0.5767846209739578 DGQDAIAQS(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 DGQDAIAQSPEK 12 0 Q9NWH9;H7BXE3;H0YL55 Q9NWH9 SLTM SAFB-like transcription modulator 1 DGQDAIAQS(1)PEK;DGQDAIAQS(1)PEK;DGQDAIAQS(1)PEK;DGQDAIAQS(1)PEK;DGQDAIAQS(1)PEK 130.01 0.00015864 199720400.0 261937.0 424180.0 258229.0 258288.0 279347.0 164419.0 294831.0 169723.0 173688.0 195564.0 True False 306277.7606084294 466289.78709204035 264386.1586989362 243816.96074099475 224610.9606592186 155796.57819689266 266902.4732884076 165267.95108638334 176227.8584145871 231018.2051162276 1.3257732673247027 2.018411435832277 1.144438632297056 1.0554015023115948 0.9722651967892079 0.6743909126923994 1.1553309106272653 0.715389295848937 0.762831043232827 1.0 17.817647020433142 -5.487717977417592 3.5309149350327127 0.901360221688553 1.6720787181771646 0.6619728957973511 0.21499706876878763 0.1255707052819901 3.217541285861684 0.056453502729659086 0.12076363309669956 3.25298471456586e-06 5.487717977417592 0.7707184964886116 DGQDAIAQS(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 2 DGQDAIAQSPEK 12 0 Q9NWH9;H7BXE3;H0YL55 Q9NWH9 SLTM SAFB-like transcription modulator 1 DGQDAIAQS(1)PEK;DGQDAIAQS(1)PEK 147.51 0.00013678 136768000.0 77685.0 136651.0 106906.0 96847.0 137388.0 113558.0 124724.0 149000.0 108434.0 103476.0 True False 76577.19765431585 136334.5930053124 98116.60134909366 103969.45145212117 129307.10795520066 108701.38905662729 131181.59844078106 155923.0839512428 96221.02105935899 121361.68872689658 0.6309832901768494 1.1233742248932423 0.8084643710742032 0.8566908761964114 1.0654689244328486 0.8956812499638243 1.0809144122572527 1.2847801113094317 0.7928451067938557 1.0 16.888953540125897 -6.426874311126673 1.302992316462346 1.0462395741275994 0.8666513395697425 0.16645246259882085 0.16663300907268105 0.7967489798379901 2.780613518624052 0.06779893506337181 0.08288572383039021 3.742188750341277e-07 6.426874311126673 -0.17958823455785689 DGQDAIAQS(ph)PEKESK ddPTM_PC-9_AZD4547_30min_R2 3 DGQDAIAQSPEKESK 15 1 Q9NWH9;H7BXE3;H0YL55 Q9NWH9 SLTM SAFB-like transcription modulator 1 DGQDAIAQS(0.991)PEKES(0.009)K;DGQDAIAQS(0.989)PEKES(0.011)K;DGQDAIAQS(1)PEKESK 149.52 0.00064762 116195000.0 120606.0 117703.0 101199.7 89868.5 103347.6 127950.0 126015.0 115321.0 110287.0 111531.0 True False 158956.19923935924 155748.19294238405 99857.72585529073 69150.70577948411 88999.56964942903 119949.26627328298 137230.09087659806 97500.78926295058 116116.54566462718 107626.33363739433 1.4769266393009466 1.447119749216004 0.927818708307235 0.6425073069241669 0.82693116676518 1.1144973745682543 1.2750605380551403 0.9059194526819255 1.0788860099595825 1.0 16.71567158913335 -5.257371197806846 23.485745000293512 0.9671348976621112 1.462023362906766 0.5960274102795617 0.1615177428619828 108.1383598999392 624269.2773549919 0.046695470630549164 0.11419361041021886 5.528773548973382e-06 5.257371197806846 0.4948884652446548 DGQDAIAQS(ph)PEKESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DGQDAIAQSPEKESK 15 1 Q9NWH9;H7BXE3;H0YL55 Q9NWH9 SLTM SAFB-like transcription modulator 1 DGQDAIAQS(0.977)PEKES(0.023)K;DGQDAIAQS(0.998)PEKES(0.002)K;DGQDAIAQS(0.999)PEKES(0.001)K;DGQDAIAQS(0.997)PEKES(0.003)K 106.87 0.0043357 81167000.0 198849.0 201808.0 143038.0 216224.0 212386.0 155026.0 195503.0 177047.0 151485.0 159400.0 True False 232510.20825322715 221842.16453739128 146448.56839463563 204109.67028766603 170770.48792565777 146896.16365232406 176983.5405208527 172399.70384680302 153700.1815435362 188297.95819029462 1.2347994130571052 1.1781442914702067 0.7777491046750181 1.083971766074022 0.906916302050798 0.7801261631518609 0.9399121595465866 0.9155686312465228 0.8162604789809044 1.0 17.522657830603997 -5.161853021688445 5.9647153436026 0.9035795062499139 1.2178787165594605 0.6415650076680506 0.09106953759829577 0.13462305722164447 6.62355183923634 0.022694706876934173 0.06231451400604307 6.888853964303837e-06 5.161853021688445 0.31429921030954655 DGQDAIAQS(ph)PEKESK ddPTM_PC-9_Lapatinib_30min_R1 6 DGQDAIAQSPEKESK 15 1 Q9NWH9;H7BXE3;H0YL55 Q9NWH9 SLTM SAFB-like transcription modulator 1 DGQDAIAQS(0.902)PEKES(0.098)K;DGQDAIAQS(0.999)PEKES(0.001)K;DGQDAIAQS(1)PEKESK;DGQDAIAQS(1)PEKESK;DGQDAIAQS(1)PEKESK;DGQDAIAQS(1)PEKESK 164.53 0.0012825999999999998 488952400.0 210294.0 267315.0 218483.0 237288.2 272288.0 251543.0 252986.0 273418.0 226460.0 226491.0 True False 207295.16899680317 266696.04854128405 200520.17110876876 254739.16579823065 256272.55517880482 240785.09226537246 266084.3772099949 286121.99844148254 200953.69007048046 265639.6675697127 0.7803622512153687 1.003976744065508 0.7548577851466615 0.9589650827709255 0.9647375240429797 0.9064350007221058 1.0016741085559653 1.0771056938113153 0.7564897664154151 1.0 18.0191110726766 DGQDAIAQS(ph)PEKESKDYEMNANHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DGQDAIAQSPEKESKDYEMNANHK 24 2 Q9NWH9;H7BXE3;H0YL55 Q9NWH9 SLTM SAFB-like transcription modulator 1 DGQDAIAQS(0.931)PEKES(0.059)KDY(0.01)EMNANHK 52.72 0.041371 14920000.0 21046.0 10392.0 14154.0 33895.0 27394.0 23934.0 23835.0 28375.0 25387.0 21677.0 True False 24608.67212255241 11423.649081664604 14491.485039343916 31995.973039072676 22026.342349474417 22678.858906601006 21577.176249543594 27630.18631579765 25758.236847514585 25606.868504962415 0.9610184126100166 0.4461165987340775 0.565921796979415 1.2495074527708103 0.8601732127146231 0.8856553038574794 0.8426323681617728 1.0790146522774986 1.0059112398895178 1.0 14.644243214343746 -5.737610578396225 24.999913521020066 0.9765066631868541 0.6365285446497656 0.455429515173271 0.16513618808508446 203.53117215633227 213532.4310709405 0.04421651339702835 0.07653261204829134 1.8297401655684349e-06 5.737610578396225 -0.3399781185370885 DGQDAIAQS(ph)PEKESKDYEMNANHK ddPTM_PC-9_Lapatinib_30min_R1 1 DGQDAIAQSPEKESKDYEMNANHK 24 2 Q9NWH9;H7BXE3;H0YL55 Q9NWH9 SLTM SAFB-like transcription modulator 1 DGQDAIAQS(0.531)PEKES(0.252)KDY(0.217)EMNANHK 67.76 0.0026998 18720000.0 102090.0 59273.0 63219.0 82053.0 69904.0 70255.0 48139.0 47500.0 66387.0 51051.0 True False 100634.1778789869 59135.75701022226 58021.3778523971 88087.45134078397 65792.38415655184 67250.35742240399 50631.40187406402 49707.0234072754 58909.79697389807 59875.09732881841 1.6807351030484385 0.9876519562960226 0.9690402260852927 1.4711867749797662 1.0988271767682853 1.1231774213757446 0.8456170283283143 0.8301785821624206 0.9838780996109423 1.0 15.869668475545483 -6.983130700657679 2.173264979920442 0.9021442129190456 1.2302045656585365 0.3529047964376133 0.2076489808759318 0.37648404745791597 3.580170670625696 0.08895415230410714 0.07058662295279951 1.039607249581986e-07 6.983130700657679 0.32806035273949097 DGQDAIAQSPEKESKDY(ph)EMNANHK ddPTM_PC-9_AZD4547_30min_R2 1 DGQDAIAQSPEKESKDYEMNANHK 24 2 Q9NWH9;H7BXE3;H0YL55 Q9NWH9 SLTM SAFB-like transcription modulator 1 DGQDAIAQS(0.016)PEKES(0.378)KDY(0.606)EMNANHK 59.537 0.0017589000000000003 24559000.0 52713.0 36724.0 53189.0 86146.0 84664.0 60744.0 43419.0 42741.0 56252.0 69939.0 True False 69474.63750148712 48594.31482303862 52483.67910692475 66286.37064243239 72909.86500701788 56945.66807740763 47283.20688625168 36136.36054047204 59225.36587926596 67490.45689777473 1.0293994246729987 0.7200175707306681 0.7776459298004134 0.9821591627811007 1.0802988801431843 0.8437588170970765 0.7005910029305297 0.5354291880881238 0.8775368933858666 1.0 16.04239590008941 -7.007637610429782 24.291371633395144 0.7443178448430383 0.9086221521985107 0.14233407951100363 0.15194123415674105 417.86830112252767 1329029.9962851591 0.056294106397412266 0.04753659410890142 9.825674876067056e-08 7.007637610429782 0.1643043073554724 DGQHYGDDR ddPTM_PC-9_AZD4547_30min_R2 2 DGQHYGDDR 9 0 Q14151 Q14151 SAFB2 Scaffold attachment factor B2 0 ; 103.88 0.0023001 12906000.0 138227.0 103050.0 126389.0 163706.0 152884.0 141470.0 118756.0 110204.0 164509.0 185762.0 False True 182180.31069979016 136358.89724741664 124712.99927889448 125966.11093248743 131658.69556993406 132623.8585360011 129325.05393914445 93174.50403598831 173204.60988822015 179258.5289215526 1.0162992622767544 0.7606828978669696 0.6957158469903073 0.7027063743651099 0.7344626577157215 0.7398468532230349 0.7214443559097814 0.519777243495976 0.9662280000301587 1.0 17.451682236823423 -8.431787765910963 9.238836155276205 0.9998488729725936 0.7343663099019133 0.43169953523625937 0.11354831336988959 0.3171795147963474 28.895680434853517 0.10927505869519512 0.028229666528899616 3.700089541897762e-09 8.431787765910963 -0.2654825630706803 DGQHYGDDR ddPTM_PC-9_Lapatinib_30min_R1 2 DGQHYGDDR 9 0 Q14151 Q14151 SAFB2 Scaffold attachment factor B2 0 ; 114.51 0.0017076 13717900.0 122119.0 159779.0 146419.0 141704.0 173147.0 121327.0 171942.0 183884.0 187429.0 148090.0 False True 120377.56066611817 159409.04154229263 134380.99501368467 152125.38487068625 162962.83388009958 116138.12703705077 180844.3154413325 192427.92194154556 166318.77230513137 173687.15918247824 0.6930711587011896 0.9177940516305825 0.7736956240530255 0.8758585584951685 0.9382549328755414 0.6686627127975211 1.0412071697904555 1.1078995295177694 0.9575766745680633 1.0 17.406131572937966 -7.292236367081082 24.47495835837404 1.0356625466220473 0.8230733761989075 0.5769704783286969 0.08990251381743822 382.3712939770161 303876.0746786568 0.03597515018289089 0.024258062420470523 5.102272305102346e-08 7.292236367081082 -0.21258917042313974 DGQPCMDHDR ddPTM_PC-9_AZD4547_30min_R2 2 DGQPCMDHDR 10 0 A0A6I8PRU9;A0A6I8PTV8;A0A6I8PIP7;A0A6I8PLB3;A0A6I8PS05;A0A6I8PLB8;A0A6I8PRS0;A0A6I8PL42;B4DER1;A0A6I8PIT3;A0A6I8PIV1;Q9P2J5-2;Q9P2J5 A0A6I8PRU9 LARS Leucine--tRNA ligase, cytoplasmic 0 ; 70.72800000000001 0.023761 5050600.0 17653.2 17345.9 19702.9 28884.0 26617.0 23737.9 21594.4 25802.0 21266.8 21140.5 False True 23266.550390629494 22952.622957437783 19441.626672353836 22225.240053351503 22921.68899286346 22253.5653604421 23516.259766104078 21814.89377097539 22390.919630967295 20400.377529667396 1.1404960695846902 1.125107754700067 0.9530032786932845 1.0894523898408393 1.1235914119495793 1.090840859590941 1.1527364987194668 1.069337748247596 1.0975737874657046 1.0 14.316308230527552 -5.0245143434015995 24.995997634540444 1.0777892644553653 1.136649096819134 0.1601441384766391 0.05488320676845771 1267.394720198476 1292301.9331188842 0.014203797945202669 0.038020941861286996 9.451171776321969e-06 5.0245143434015995 0.058859832363768794 DGQPCMDHDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DGQPCMDHDR 10 0 A0A6I8PRU9;A0A6I8PTV8;A0A6I8PIP7;A0A6I8PLB3;A0A6I8PS05;A0A6I8PLB8;A0A6I8PRS0;A0A6I8PL42;B4DER1;A0A6I8PIT3;A0A6I8PIV1;Q9P2J5-2;Q9P2J5 A0A6I8PRU9 LARS Leucine--tRNA ligase, cytoplasmic 0 62.799 0.039310000000000005 2685300.0 8786.7 8971.1 9721.6 12356.0 12154.0 11505.0 10065.0 8110.1 9264.6 8479.0 False True 10274.114764764377 9861.691520065573 9953.399813373308 11663.733378692481 9772.510948219022 10901.657546605018 9111.57033571036 7897.218468361245 9400.077248098778 10016.17558027293 1.025752262669942 0.984576542317048 0.9937325612558889 1.1644897081940588 0.9756728873110202 1.0884051960986052 0.909685564384054 0.7884464888889313 0.9384896633214408 1.0 13.290044137125191 -7.350327292164677 6.123082766816392 0.8892465831108058 1.0368670277563155 0.4261558454229053 0.07241799224759934 0.2061085345486615 11.588972332385724 0.029949030090494894 0.020031136660965607 4.463470901419842e-08 7.350327292164677 0.1476204446455096 DGQPCMDHDR ddPTM_PC-9_Lapatinib_30min_R1 1 DGQPCMDHDR 10 0 A0A6I8PRU9;A0A6I8PTV8;A0A6I8PIP7;A0A6I8PLB3;A0A6I8PS05;A0A6I8PLB8;A0A6I8PRS0;A0A6I8PL42;B4DER1;A0A6I8PIT3;A0A6I8PIV1;Q9P2J5-2;Q9P2J5 A0A6I8PRU9 LARS Leucine--tRNA ligase, cytoplasmic 0 70.72800000000001 0.023761 1420200.0 16345.0 16456.0 16879.0 13620.0 20835.0 19020.0 15974.0 17163.0 17899.0 14115.0 False True 16111.917302694104 16417.897143053626 15491.273774824205 14621.660234988085 19609.526263186046 18206.558937785532 16801.055558617725 17960.45563661195 15883.026135174096 16554.75894294474 0.973249888942698 0.9917327820741575 0.9357595497593296 0.8832300298289455 1.1845250257505668 1.0997779551205578 1.014877692663592 1.0849119397335765 0.9594235826637076 1.0 14.014958383075049 -6.241845574208804 24.99950022418914 1.0615058223370082 0.9485292250757161 0.42247280396816755 0.06358378972728597 834.8567673719463 1065183.4207169346 0.019198172226679796 0.024752521989973585 5.729997411688652e-07 6.241845574208804 -0.11297659726129206 DGQS(ph)SPQPSPR ddPTM_PC-9_AZD4547_30min_R2 2 DGQSSPQPSPR 11 0 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 DGQS(0.5)S(0.5)PQPSPR;DGQS(0.5)S(0.5)PQPSPR 104.94 0.0026206999999999997 4372600.0 19604.5 24134.0 29779.0 42463.0 36634.0 29468.0 26737.0 35660.0 27748.0 33416.0 True False 25838.32320106813 31934.84353390735 29384.111002747057 32673.81139681018 31548.001448869494 27625.361301610832 29116.5412035678 30149.566385279533 29214.702631335247 32246.11601103882 0.8012848180606587 0.9903469776941536 0.9112449695550306 1.0132634697966398 0.9783504294926453 0.8567035264697874 0.9029472322682313 0.9349828790220325 0.9059913640865824 1.0 14.976837780424558 -6.070837576073334 0.005927618146193715 1.8505351218793982 1.471292161600468e-07 0.08209923496284899 0.06167089879912198 45973.55633199661 70.5265050394979 10728.36770608742 11290.11243233114 8.494981236093633e-07 6.070837576073334 -1.850534974750182 DGQS(ph)SPQPSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DGQSSPQPSPR 11 0 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 DGQS(0.499)S(0.499)PQPS(0.001)PR 89.189 0.026077999999999997 0.0 7918.9 9081.7 10117.0 12278.0 14997.0 15923.0 16473.0 14467.0 13749.0 13966.0 True False 9259.41336459566 9983.271157135634 10358.227648936156 11590.10346581308 12058.445506865284 15087.969849160523 14912.558185807924 14087.256579053548 13950.053114447475 16497.925245204835 0.5612471402903788 0.6051228265831364 0.6278503202665924 0.702518849706982 0.7309067854074622 0.9145374115176016 0.9039050646772872 0.8538804952548834 0.8455640880359847 1.0 14.009996984223038 -6.298328910459122 1.0511698142359973 0.9028915622393294 0.58106821277995 0.888741273823985 0.0473260999778498 0.16534220104453182 0.38405201429006197 0.021556396389560306 0.03165742535614965 5.031194298217522e-07 6.298328910459122 -0.3218233494593794 DGQS(ph)SPQPSPR ddPTM_PC-9_Lapatinib_30min_R1 1 DGQSSPQPSPR 11 0 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 DGQS(0.5)S(0.5)PQPSPR 108.32 0.0021994 59745000.0 29949.0 28423.0 24688.0 23747.0 28006.0 27080.0 26013.0 28246.0 33935.0 22231.0 True False 29521.921768026044 28357.18828980393 22658.247938435903 25493.43359766975 26358.742141914492 25921.8515265632 27359.82585741347 29558.412277092637 30112.882948607905 26073.598729054494 1.1322534366968298 1.087582446308218 0.8690111470185059 0.9777489430050079 1.01093609730759 0.994180043803382 1.0493306329411942 1.133652956166535 1.1549185542635636 1.0 14.670302099755025 -7.552527734881558 4.255855673231229 1.1074198365043955 1.0079040283152456 0.1945537911833073 0.07534781649521732 0.3106652507740762 12.937167701439249 0.03855038209120174 0.0221365268321962 2.8020266731360345e-08 7.552527734881558 -0.09951580818914985 DGQSS(ph)PQPSPR ddPTM_PC-9_AZD4547_30min_R2 3 DGQSSPQPSPR 11 0 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 DGQS(0.084)S(0.916)PQPSPR;DGQS(0.23)S(0.77)PQPSPR;DGQS(0.232)S(0.73)PQPS(0.037)PR 158.11 0.0003432 161745100.0 125916.0 133652.0 179911.0 232607.0 217547.0 179779.0 152758.0 198983.0 161785.0 186508.0 True False 165954.66878449806 176852.39529269017 177525.26258824102 178983.04989232548 187344.35418456118 168537.3907100003 166353.16606854182 168234.7495244549 170336.62480937652 179978.41168861662 0.9220809719757876 0.9826311591118227 0.9863697591430031 0.9944695489478304 1.0409268113149508 0.9364311482067604 0.924295111328974 0.9347496066112663 0.9464280921874035 1.0 17.4574643408938 DGQSS(ph)PQPSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DGQSSPQPSPR 11 0 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 DGQS(0.004)S(0.996)PQPSPR;DGQS(0.188)S(0.812)PQPSPR;DGQS(0.082)S(0.918)PQPSPR;DGQS(0.106)S(0.894)PQPSPR 147.73 0.00014078 128557100.0 85380.0 103981.0 134069.0 155407.0 216413.0 211015.0 206236.0 199451.0 191228.0 154917.0 True False 99833.14766813292 114303.54649351128 137265.71341951372 146700.04962629202 174008.42618371948 199949.00192932287 186699.8330606621 194215.6225858028 194024.34773216676 183002.22577770238 0.5455296909306605 0.6246019468219955 0.750076742707239 0.801629865444874 0.9508541518784154 1.0926042078428388 1.0202052585275727 1.0612746471276346 1.060229442060739 1.0 17.481501669934794 -5.827101985097977 0.9157200851259136 1.0579918208722372 0.5391508823711854 0.9617204136060794 0.03652964294907687 0.12250004785744173 0.19514301141624665 0.015928752477394982 0.04604216305937431 1.489011373054898e-06 5.827101985097977 -0.5188409385010518 DGQSS(ph)PQPSPR ddPTM_PC-9_Lapatinib_30min_R1 2 DGQSSPQPSPR 11 0 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 DGQS(0.226)S(0.774)PQPSPR;DGQS(0.079)S(0.921)PQPSPR 156.52 0.00029502 62765700.0 51066.0 53015.0 51363.0 46108.0 55076.0 53325.0 54255.0 47309.6 62526.0 41691.0 True False 50337.78947564252 52892.24702473186 47140.13240691364 49498.93613177906 51836.53796358216 51044.41405664635 57064.05842824614 49507.77672818599 55483.66345203057 48897.233800234404 1.0294608828240344 1.081702233725915 0.9640654234041284 1.0123054472570547 1.060111870036576 1.043912100737315 1.167020176670456 1.012486246777188 1.1346994326653421 1.0 15.577465231320732 -6.629748909698755 2.2692415744147705 1.07979931010783 1.0232677720527308 0.1507887527303956 0.054629900210867985 0.5289944934152486 5.5538446721287755 0.019570020452377546 0.01963959466291948 2.3455845389869082e-07 6.629748909698755 -0.05653153805509925 DGQVINETS(ph)QHHDDLE ddPTM_PC-9_Lapatinib_30min_R1 2 DGQVINETSQHHDDLE 16 0 P08670 P08670 VIM Vimentin 1 DGQVINET(0.24)S(0.76)QHHDDLE;DGQVINET(0.108)S(0.892)QHHDDLE 151.38 3.1109e-05 34021000.0 208253.0 147469.0 205991.0 160222.0 182516.0 159273.0 169464.0 178665.0 168530.0 148037.0 True False 205283.27403107678 147127.5445909682 189055.21512825464 172005.26036492398 171780.76772026243 152461.26507349705 178238.01672627978 186966.42814864978 149548.37670042395 173624.9982030968 1.182337083689688 0.8473868746645955 1.0888709407334791 0.9906710562710668 0.9893780820623705 0.878106647380099 1.0265688614596093 1.0768404900424933 0.8613297523291585 1.0 17.405615153712546 -4.73454707615758 24.887495123304145 0.9789967040883044 1.1823381878055579 0.3719500767845111 0.08120316616838232 3005.5313058704096 2781314.907728741 0.019274474041338367 1.6777610229618822 1.8426927360403576e-05 4.73454707615758 0.20334148371725347 DGQVINETSQHHDDLE ddPTM_PC-9_Lapatinib_30min_R1 3 DGQVINETSQHHDDLE 16 0 P08670 P08670 VIM Vimentin 0 ;; 133.23 3.1487e-06 29520400.0 147968.0 179401.0 195053.0 257140.0 296635.0 393200.0 253423.0 204089.0 293890.0 195692.0 False True 145857.94918599186 178985.6080068647 179016.49526635392 276050.9333938941 279187.5125068486 376383.75259396824 266544.0029317377 213571.72000352418 260789.01340110134 229517.10145680082 0.6354992645872399 0.7798356064572075 0.7799701814378655 1.2027466870299937 1.216412680078206 1.6398941525706323 1.1613252399926546 0.9305263906172244 1.1362509013307074 1.0 17.808242128153132 -5.731820923250246 4.630268888337144 1.2021917402322648 0.7258669946635509 0.5694826004710504 0.1800847070331478 0.1513659064912985 7.578432240079651 0.054706335479444854 0.09335074659982188 1.8542960652272107e-06 5.731820923250246 -0.47632474556871396 DGQWFTDWDAVPHSR ddPTM_PC-9_AZD4547_30min_R2 2 DGQWFTDWDAVPHSR 15 0 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 0 ; 187.75 2.5064e-07 12878000.0 65404.0 46831.0 73163.0 118506.0 100481.0 86027.0 56904.0 89262.0 68679.0 84957.0 False True 86201.11151228836 61968.20491988129 72192.8108161451 91186.27259944865 86530.94757831126 80647.71809059585 61968.3457623452 75468.60893670267 72309.23172904261 81982.68128889815 1.0514551385374298 0.7558694585934802 0.880586115032581 1.1122626287144481 1.0554783793102047 0.9837165218639528 0.7558711765473419 0.9205433117118896 0.8820061821866091 1.0 16.323031554432347 -9.88049755999861 10.711472544791558 1.0 0.9311086567431679 0.029365032914711264 0.114903268179295 0.0 0.0 0.1177878951089647 0.02856776076196679 1.316747310596512e-10 9.88049755999861 -0.0688913432568321 DGQWFTDWDAVPHSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DGQWFTDWDAVPHSR 15 0 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 0 ; 169.15 9.390200000000001e-05 11712400.0 93766.0 75984.0 104697.0 113661.0 128927.0 109393.0 114644.0 116656.0 116489.0 89582.0 False True 109638.73183708297 83527.18935923827 107193.37354558332 107292.94266393394 103664.67986021355 103656.2385046297 103784.09036931721 113593.90360724906 118192.43124946348 105822.50746927815 1.036062501816192 0.789314025501498 1.0129543904136193 1.0138952972276023 0.979608991880191 0.9795292228803277 0.9807373955814389 1.0734380267848695 1.1168931267648945 1.0 16.691286982426377 -6.7185426392307805 0.5796034447443913 1.0614696296318875 0.929600737626593 0.22380418736830288 0.0717272159641846 1.2419059411852897 0.9083660342930651 0.05945300968669569 0.07228188449575719 1.9118656075502102e-07 6.7185426392307805 -0.1318688920052945 DGQWFTDWDAVPHSR ddPTM_PC-9_Lapatinib_30min_R1 1 DGQWFTDWDAVPHSR 15 0 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 0 175.26 5.2573999999999995e-05 4834600.0 37145.0 33666.0 40596.0 30734.0 31488.0 31628.0 26967.0 21615.0 34544.0 24661.0 False True 36615.305488441256 33588.04844543287 37258.35358509173 32994.28088561848 29635.937747789878 30275.344168469033 28363.21930945561 22619.311809436993 30653.290955553588 28923.62099128302 1.2659308977764696 1.1612670645752 1.288163525456257 1.140738253193204 1.0246275096994784 1.0467342307380323 0.9806247744016455 0.7820359634865215 1.0598012940631414 1.0 14.81996055629056 -6.36344486749919 1.1530875465075145 0.9449041658023751 1.239232613036913 0.6919496722930005 0.07801650190047216 0.2615518670226422 0.7241244864231217 0.033648219594524714 0.0448849845425615 4.3306704092910547e-07 6.36344486749919 0.29432844723453777 DGRHPQGEQMYR ddPTM_PC-9_AZD4547_30min_R2 3 DGRHPQGEQMYR 12 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ;; 92.24700000000001 0.0026875999999999996 2884250.0 8051.0 5798.3 10639.0 22088.6 17762.8 11718.0 5832.83 11081.7 10016.4 13857.599999999999 False True 10611.05052879693 7672.48708306352 10497.91990860089 16996.414535468088 15296.741828246408 10985.271607583676 6351.940570311049 9369.277897132699 10545.846455114113 13372.449641925159 0.7935008777695658 0.5737532979005449 0.7850409004860206 1.2710023212337336 1.1438997519413518 0.8214853599554992 0.47500201835843997 0.7006403574524027 0.7886248770794313 1.0 13.70697615033154 -7.00363781976646 24.960398675101143 0.7064235259992178 0.9148386544584075 0.11477877123643765 0.21766135274793982 306.22870046362357 2101158.7320686807 0.0859103973184785 0.07418271499187705 9.916585946372414e-08 7.00363781976646 0.20841512845918975 DGRHPQGEQMYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DGRHPQGEQMYR 12 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 65.695 0.028067 1117100.0 2791.1 1332.0 2515.5 5377.0 3993.6 5230.1 4325.4 6220.8 6258.9 5782.4 False True 3263.578103262186 1464.232157118673 2575.479060086875 5075.744122469205 3211.082748297472 4955.824348935154 3915.6667988158515 6057.51059148243 6350.424571824521 6830.7033465467875 0.47778068197209356 0.21436037884135387 0.3770444900654176 0.7430778157032994 0.47009547705227334 0.7255218236699644 0.5732450379059996 0.886806275161219 0.9296882399430992 1.0 12.737818422816035 -6.898956762803506 0.3613473830090499 1.0395272985058257 0.2469068653877606 0.7293331891254925 0.12768292260257424 0.8550853906866315 0.24243384847905494 0.14896328406098364 0.2524196579473925 1.261953165017114e-07 6.898956762803506 -0.7926204331180651 down DGRHPQGEQMYR ddPTM_PC-9_Lapatinib_30min_R1 2 DGRHPQGEQMYR 12 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 93.839 0.0022976 1719640.0 9149.900000000001 4368.8 8331.1 5989.5 5962.8 7230.9 6090.4 5772.4 6844.6 3540.3 False True 9019.420748113844 4358.684312018273 7646.149116976002 6429.987810386283 5612.0798273158525 6921.6512630511825 6405.731111443929 6040.606777182242 6073.689071166689 4152.236137846778 2.1721839627336412 1.0497197575758668 1.8414533430030453 1.548560244871015 1.3515801223737975 1.666969563691659 1.5427184049233156 1.45478401917544 1.4627513632488922 1.0 12.019672776819641 -12.5054059041419 0.18814175026032293 7.945958622516757e-14 1.679746052093609 0.3128095957526573 0.27215879122180064 71.61669309899563 1.383538244943571 29.543525130378157 0.7664527886222872 3.1231590081724766e-13 12.5054059041419 1.6797460520935295 DGS(ph)FGEGLTMK ddPTM_PC-9_Lapatinib_30min_R1 4 DGSFGEGLTMK 11 0 Q9ULT0;Q9ULT0-4;G5E9G4 Q9ULT0 TTC7A Tetratricopeptide repeat protein 7A 1 DGS(0.99)FGEGLT(0.01)MK;DGS(1)FGEGLTMK;DGS(1)FGEGLTMK;DGS(1)FGEGLTMK 140.01 9.831e-05 19978700.0 117785.3 196477.6 128664.3 141964.4 152958.1 141942.8 154217.9 156591.4 137574.0 132541.1 True False 116105.66002282155 196022.66818874772 118086.01791256064 152404.93555535574 143961.405285195 135872.23732882782 162202.54826801992 163867.20810901077 122078.96740155532 155450.6525350858 0.7468972186952774 1.2609961102897569 0.7596366820390682 0.980407177904624 0.9260907107012779 0.8740538242395666 1.043434335094928 1.0541429414201096 0.7853229652670749 1.0 17.246097147128374 -7.2551174044117355 24.82119070828575 0.9752369700943344 0.9350625472987293 0.018941394583958604 0.15027620554910895 2843.555070096352 11164335.70496635 0.0555856546588883 0.041953237363339814 5.55753997955412e-08 7.2551174044117355 -0.040174422795605125 DGS(ph)ISPVSSECSVVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DGSISPVSSECSVVER 16 0 H0YCZ0;H7BY22;H0YEM9;Q8NCP5-3;Q8NCP5-4;Q8NCP5-2;Q8NCP5 H0YCZ0 ZBTB44 Zinc finger and BTB domain-containing protein 44 1 DGS(0.99)IS(0.01)PVSSECSVVER;DGS(0.499)IS(0.499)PVS(0.003)SECSVVER 211.49 1.1748e-17 18764500.0 40103.0 35373.0 35690.0 43674.0 52942.0 38030.0 43588.0 37946.0 35464.0 30494.0 True False 46891.64582964547 38884.59766798714 36540.98495507873 41227.08737301844 42568.39514732691 36035.63985201122 39459.02909020795 36949.95770711038 35982.59390870356 36022.32080962883 1.3017386102760835 1.0794584244997678 1.0143984100355705 1.1444872636301204 1.1817227260923262 1.0003697441498225 1.0954049656806255 1.0257517249480936 0.998897158760669 1.0 15.136603512283981 -4.76354856714784 5.307201705579854 1.0642415281256752 1.3142153497434095 0.5829260072517335 0.061368686101166504 0.11807887841384287 9.822208204614512 0.015789216041012424 0.10902505421169839 1.7236593234425815e-05 4.76354856714784 0.2499738216177343 DGS(ph)PEAPAS(ph)PEREEVALSEYK ddPTM_PC-9_AZD4547_30min_R2 1 DGSPEAPASPEREEVALSEYK 21 1 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 2 DGS(1)PEAPAS(1)PEREEVALSEYK 69.649 0.009600299999999999 4387100.0 31302.0 37192.0 25966.0 20575.0 27277.0 29894.0 31977.0 30421.0 30553.0 26614.0 True False 41255.38487795323 49213.58667079979 25621.673874117012 15831.751630581188 23490.059385292705 28024.723454267478 34822.89105234275 25720.133455036117 32167.96920481425 25682.251960671132 1.606377234408035 1.9162488844889338 0.9976412470897456 0.6164471735120953 0.9146417308444964 1.0912097388182127 1.3559126787506508 1.0014750067253835 1.2525369369506658 1.0 14.648484090967921 -5.267576614167411 24.95100918044908 1.0239028304508202 1.7613130778607746 0.6850074997340004 0.1986873730179439 253.66351118998517 1031276.0891642881 0.05631825574481863 0.12215288879527687 5.400368381168507e-06 5.267576614167411 0.7374102474099544 DGSIS(ph)PVSSECSVVER ddPTM_PC-9_AZD4547_30min_R2 1 DGSISPVSSECSVVER 16 0 H0YCZ0;H7BY22;H0YEM9;Q8NCP5-3;Q8NCP5-4;Q8NCP5-2;Q8NCP5 H0YCZ0 ZBTB44 Zinc finger and BTB domain-containing protein 44 1 DGS(0.374)IS(0.576)PVS(0.047)S(0.004)ECSVVER 120.59 8.9433e-05 11833000.0 16209.0 16821.0 21944.0 27902.0 29348.0 21715.0 17310.0 27784.0 20349.0 22232.0 True False 21363.124831855614 22258.059297416745 21653.008222045097 21469.624981602763 25273.536783354848 20357.157617228146 18850.556466086662 23490.621212804454 21424.60659669315 21453.66444689416 0.995779759897771 1.0374945199927856 1.0092918287057386 1.0007439537775988 1.178052208559349 0.9488895320246908 0.8786637132667399 1.094946798993362 0.9986455530581761 1.0 14.388936471462328 DGSIS(ph)PVSSECSVVER ddPTM_PC-9_Lapatinib_30min_R1 1 DGSISPVSSECSVVER 16 0 H0YCZ0;H7BY22;H0YEM9;Q8NCP5-3;Q8NCP5-4;Q8NCP5-2;Q8NCP5 H0YCZ0 ZBTB44 Zinc finger and BTB domain-containing protein 44 1 DGS(0.001)IS(0.997)PVS(0.001)SECSVVER 160.04 5.4272e-05 10964000.0 20655.0 22221.0 25880.0 25139.0 23382.0 26298.0 20071.0 21219.0 27274.0 20134.0 True False 20360.455912336907 22169.54863975417 23752.24629968897 26987.80592124563 22006.716730780696 25173.295843632164 21110.17817184276 22204.91220376793 24202.114912047517 23614.13507313136 0.8622147645586835 0.9388253506256569 1.0058486675937903 1.1428665855288047 0.9319298234988239 1.0660265881291942 0.893963641118592 0.9403229097742024 1.024899486561554 1.0 14.527363073684711 -4.939448885579732 2.8280007877352658 0.9992089089664968 0.8582807032738182 0.2952790291135948 0.06708539029424686 0.4196428540379328 5.859937310992008 0.017920685319780902 0.11665875002431235 1.1496115393353049e-05 4.939448885579732 -0.1409282056926786 DGSISPVS(ph)SECSVVER ddPTM_PC-9_AZD4547_30min_R2 1 DGSISPVSSECSVVER 16 0 H0YCZ0;H7BY22;H0YEM9;Q8NCP5-3;Q8NCP5-4;Q8NCP5-2;Q8NCP5 H0YCZ0 ZBTB44 Zinc finger and BTB domain-containing protein 44 1 DGS(0.004)IS(0.367)PVS(0.604)S(0.025)ECSVVER 217.32 4.0121e-22 12377000.0 11045.0 10019.0 12239.0 19159.0 15727.0 13250.0 12121.0 12324.0 10508.0 8996.8 True False 14557.080249728244 13257.445817776486 12076.702863179462 14742.188553599279 13543.577517780488 12421.475405400544 13199.745518511634 10419.608977346741 11063.43142749283 8681.824770412797 1.6767304840496216 1.527034485072443 1.3910327819948902 1.6980518431839218 1.5599920380720294 1.4307447724275983 1.5203883823474154 1.2001634740263616 1.2743209774512407 1.0 13.083782588915208 -8.10600777905381 0.7416441860840564 1.0104662945216265 1.5705769911363983 0.7716067183802628 0.09917478326231767 0.2917576665566576 0.33813107007150617 0.09359009192696485 0.03946943571494979 7.834156101523497e-09 8.10600777905381 0.5601106966147718 DGSISPVS(ph)SECSVVER ddPTM_PC-9_Lapatinib_30min_R1 1 DGSISPVSSECSVVER 16 0 H0YCZ0;H7BY22;H0YEM9;Q8NCP5-3;Q8NCP5-4;Q8NCP5-2;Q8NCP5 H0YCZ0 ZBTB44 Zinc finger and BTB domain-containing protein 44 1 DGS(0.003)IS(0.359)PVS(0.552)S(0.084)ECS(0.001)VVER 197.75 5.7742e-12 9961900.0 21759.0 24694.0 30732.0 21194.0 25262.0 29924.0 27688.0 25069.0 32162.0 22359.0 True False 21448.71266988809 24636.822560194847 28205.333588950598 22752.6774611114 23776.13882700293 28644.220276251028 29121.54916157552 26233.79725888393 28539.576879125594 26223.723358505216 0.8179125586653798 0.9394860608992931 1.0755655557891126 0.867637182945341 0.9066652550424937 1.0923018018705861 1.1105039800585923 1.0003841521755317 1.0883113922824872 1.0 14.678584919780599 -6.759002305590407 24.99933958950572 1.0615870149450104 0.9280271339356607 0.48354007606001814 0.07051000945202637 61.003940398082136 625775.1572714907 0.024499516779259538 0.023417743179741348 1.7417976264803005e-07 6.759002305590407 -0.13355988100934968 DGSPEAPAS(ph)PEREEVALSEYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DGSPEAPASPEREEVALSEYK 21 1 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 DGS(0.001)PEAPAS(0.971)PEREEVALS(0.026)EY(0.002)K;DGS(0.025)PEAPAS(0.95)PEREEVALS(0.025)EY(0.001)K 59.339 0.0054731 25165000.0 57952.0 61418.0 49369.0 53398.0 65575.0 53270.0 57005.0 45854.0 50827.0 44328.0 True False 67762.12899582613 67515.1731425785 50546.144192975116 50406.28317865179 52726.049484076204 50476.427423524496 51605.0737195399 44650.38108632898 51570.24871976304 52364.3154997451 1.294051652334804 1.2893355426923732 0.9652784288418926 0.9626075066119629 1.0069080246896929 0.9639470494705542 0.9855007790523129 0.8526871908894966 0.9848357269181544 1.0 15.676296378542393 -5.26141294889012 7.496244860359463 0.9617730369416759 1.292912034712801 0.9117478819823139 0.040619961535619725 0.02913134843494765 14.5433302022926 0.010718450332544077 0.025229341591761288 5.47755883565832e-06 5.26141294889012 0.331138997771125 DGSPEAPAS(ph)PEREEVALSEYK ddPTM_PC-9_Lapatinib_30min_R1 2 DGSPEAPASPEREEVALSEYK 21 1 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 DGS(0.006)PEAPAS(0.985)PEREEVALS(0.006)EY(0.002)K;DGS(0.005)PEAPAS(0.995)PEREEVALSEYK 91.618 0.00019462 24689000.0 59217.0 62484.0 58686.0 49982.0 55138.0 63794.0 56374.0 51208.0 60329.0 56536.0 True False 58372.5547209322 62339.3221370055 53861.06361451108 53657.84301506422 51894.891245478844 61065.67933107734 59292.76987989956 53587.3106239949 53534.112727466214 66308.1722705154 0.8803221793354746 0.9401453848355479 0.8122839428415515 0.8092191532011769 0.7826319059702757 0.9209374537115815 0.894200033715372 0.8081554473463152 0.8073531646908432 1.0 16.016899068402694 DGT(ph)SPEEEIEIER ddPTM_PC-9_AZD4547_30min_R2 2 DGTSPEEEIEIER 13 0 Q9H501 Q9H501 ESF1 ESF1 homolog 1 DGT(0.63)S(0.37)PEEEIEIER;DGT(0.5)S(0.5)PEEEIEIER 183.28 0.00014309 26265000.0 46601.0 47945.0 48605.0 60248.0 56608.0 51800.0 50513.0 65313.0 55109.0 48727.0 True False 61419.14863898471 63442.283634423955 47960.465942057184 46358.75442232105 48748.95632520619 48560.93781130175 55008.55914335269 55220.37659343131 58021.94923274666 47021.082561344505 1.3062044787857925 1.349230604200915 1.0199779190427432 0.9859142303208487 1.0367467882434964 1.0327481879633105 1.1698701124455735 1.1743748460361343 1.2339560484820875 1.0 15.521020133936053 -5.255254319687971 24.95691580456294 1.0843006618510294 1.3277175702402264 0.5997154797762827 0.08037461927314297 357.38600629110834 1442054.3596578664 0.022963719520705667 0.05755556373276957 5.555788190794256e-06 5.255254319687971 0.24341690838919705 DGTAPPPQSPGSPGT(ph)GQDEEWSDEESPRK ddPTM_PC-9_AZD4547_30min_R2 1 DGTAPPPQSPGSPGTGQDEEWSDEESPRK 29 1 A0A0C4DGG1;Q9UKS6 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 1 DGTAPPPQS(0.013)PGS(0.006)PGT(0.472)GQDEEWS(0.472)DEES(0.037)PRK 60.621 0.00094415 19382000.0 19137.0 18439.0 27354.0 38810.0 35193.0 28861.0 23675.0 32719.0 28304.0 27551.0 True False 25222.167925672195 24399.04615570225 26991.268087213895 29862.954108522787 30307.059425398944 27056.317107567196 25782.02913544781 27663.030357822787 29800.09165623875 26586.44787587173 0.9486851362555404 0.9177249352609216 1.0152265625416457 1.1232397140057442 1.1399439130378834 1.0176732609745092 0.969743278824624 1.0404936562784717 1.1208752592813849 1.0 14.698403416083448 -5.4244790594601895 4.265000371782626 1.0592052930213733 0.9349274852928485 0.46098435891535483 0.053582096183667466 0.21139128859250356 6.559533169514138 0.015624176006190562 0.034003539409042584 3.7628849547377465e-06 5.4244790594601895 -0.12427780772852481 DGTAPPPQSPGSPGTGQDEEWS(ph)DEESPRK ddPTM_PC-9_AZD4547_30min_R2 3 DGTAPPPQSPGSPGTGQDEEWSDEESPRK 29 1 A0A0C4DGG1;Q9UKS6 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 1 DGTAPPPQSPGSPGT(0.028)GQDEEWS(0.968)DEES(0.005)PRK;DGTAPPPQS(0.004)PGS(0.011)PGT(0.404)GQDEEWS(0.556)DEES(0.025)PRK;DGTAPPPQS(0.003)PGS(0.005)PGT(0.109)GQDEEWS(0.874)DEES(0.009)PRK 80.477 1.0246e-06 44118000.0 73240.0 77496.0 91911.0 114940.0 115512.0 100761.0 83148.0 99460.0 91493.0 95614.0 True False 96528.79651336328 102545.0664831227 90692.20008641946 88442.3588052979 99475.15268225734 94460.39874140132 90548.01092098048 84090.74236342966 96329.13319333845 92266.58296263673 1.0461945529342138 1.1113998501998088 0.9829365862952265 0.9585524462427806 1.0781276328672507 1.0237769266870214 0.9813738410324333 0.9113889304590604 1.0440305699014218 1.0 16.493520607881294 -7.237020958345276 4.685201588110712 0.9764240264751883 1.0338452987975801 0.1802544010764493 0.05078416974868476 0.32953443493974516 19.17389234218125 0.02125767743431008 0.01556213917099646 5.7940073481518254e-08 7.237020958345276 0.0574212723223918 DGTAPPPQSPGSPGTGQDEEWS(ph)DEESPRK ddPTM_PC-9_Lapatinib_30min_R1 4 DGTAPPPQSPGSPGTGQDEEWSDEESPRK 29 1 A0A0C4DGG1;Q9UKS6 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 1 DGTAPPPQSPGS(0.001)PGT(0.023)GQDEEWS(0.964)DEES(0.012)PRK;DGTAPPPQSPGS(0.001)PGT(0.088)GQDEEWS(0.91)DEES(0.001)PRK;DGTAPPPQSPGSPGT(0.007)GQDEEWS(0.982)DEES(0.01)PRK;DGTAPPPQSPGS(0.003)PGT(0.091)GQDEEWS(0.901)DEES(0.004)PRK 86.508 2.1934e-08 111487000.0 206195.0 167898.0 174801.0 147875.0 164647.0 153312.0 135633.0 144171.0 172685.0 121838.0 True False 203254.6214884677 167509.2424966221 160429.5365313731 158750.22079653898 154962.7871684566 146755.20314772747 142655.4130826342 150869.71098211186 153235.39684633425 142897.53596106955 1.4223801699690721 1.172233246500889 1.1226893133768234 1.1109374260994136 1.084432884907645 1.0269960371304716 0.9983056189401242 1.0557894505837682 1.072344570644529 1.0 17.124621514121806 -1.5228787453681616 0.661733220482765 1.0391033570717687 36.978293968178015 0.9319862159786914 0.030633874090039818 56.9659489796403 0.3514837342429299 0.013299782351348445 3006.9471280396206 0.02999999999393333 1.5228787453681616 35.93919061110625 DGTDT(ph)SQSGEDGGCWQR ddPTM_PC-9_AZD4547_30min_R2 1 DGTDTSQSGEDGGCWQR 17 0 Q9NPI1;Q9NPI1-2 Q9NPI1 BRD7 Bromodomain-containing protein 7 1 DGT(0.105)DT(0.395)S(0.395)QS(0.105)GEDGGCWQR 101.01 0.005640399999999999 0.0 5895.9 6982.8 9453.7 8580.3 7619.6 8841.4 6260.6 7056.4 7881.6 8581.0 True False 7770.673557661636 9239.853543903551 9328.337761062156 6602.244399313532 6561.750063869795 8288.545860325163 6817.781271610747 5965.9955199407295 8298.2052853947 8280.581801853128 0.9384212056117387 1.1158459351051573 1.1265316839179764 0.7973164878144193 0.7924262112115513 1.0009617752306066 0.8233456820733276 0.7204802346865998 1.002128290494954 1.0 13.015516421125863 -5.76032739394716 24.999945409020064 0.8644662419900987 1.0658242589238422 0.38665581315978126 0.10511524600437178 27.412743328936145 616266.5081847718 0.028599946038396735 0.0461752389486817 1.7364912770515805e-06 5.76032739394716 0.20135801693374356 DGTGVVEFVR ddPTM_PC-9_Lapatinib_30min_R1 2 DGTGVVEFVR 10 0 J3KTL2;Q07955;Q07955-3;Q07955-2;J3KSR8 J3KTL2 SRSF1 Serine/arginine-rich splicing factor 1 0 ; 138.06 0.00054583 18918600.0 76842.0 55323.0 76940.0 96647.0 77015.0 80509.0 76385.0 73446.0 75016.0 63773.0 False True 75746.21898890311 55194.90299253502 70614.29019698894 103754.74278494089 72485.12911731565 77065.8177456454 80339.84154532455 76858.56928780535 66566.90812649984 74796.07807781904 1.0127030846469722 0.7379384643016892 0.9440908134718066 1.3871682239407364 0.9691033404438795 1.0303457042956836 1.0741183710426327 1.0275748577063153 0.8899785902844072 1.0 16.19067500412733 -5.529947772903177 24.998579708633315 1.0602795491228048 0.8667441696982612 0.22232720045766985 0.13706108378106782 214.45644590734716 758391.5808530333 0.03679635067198826 0.06391076462768638 2.9515641525626105e-06 5.529947772903177 -0.19353537942454357 DGTS(ph)PEEEIEIER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DGTSPEEEIEIER 13 0 Q9H501 Q9H501 ESF1 ESF1 homolog 1 DGT(0.146)S(0.854)PEEEIEIER;DGT(0.046)S(0.954)PEEEIEIER 139.77 6.9885e-05 24378000.0 71126.0 74385.0 79244.0 88970.0 80876.0 52388.0 95521.0 80611.0 85150.0 64217.0 True False 83166.2269974657 81769.45120666124 81133.47749454345 83985.29934463195 65028.92837322378 49640.681056196765 86472.55936784789 78495.04666441472 86395.1576620265 75859.03375850775 1.0963259466528392 1.0779131654506557 1.0695295401840543 1.107123241405811 0.8572338079105924 0.6543806135762895 1.139911162632622 1.0347488331356625 1.1388908265963393 1.0 16.211033375216836 -6.229632409693307 24.708184477538087 0.9652267924165874 1.0857227637760785 0.15623407352181395 0.13262645977848347 1217.9043953573341 946088.1135442132 0.04261593230216945 0.05501191640180537 5.893422682981979e-07 6.229632409693307 0.12049597135949108 DGTS(ph)PEEEIEIER ddPTM_PC-9_Lapatinib_30min_R1 2 DGTSPEEEIEIER 13 0 Q9H501 Q9H501 ESF1 ESF1 homolog 1 DGT(0.152)S(0.848)PEEEIEIER;DGT(0.011)S(0.989)PEEEIEIER 193.11 1.4894999999999999e-06 26666000.0 73586.0 78908.0 85050.0 69722.0 90044.0 85770.0 98112.0 80421.0 78028.0 65797.0 True False 72536.65014598047 78725.2933740929 78057.51730249409 74849.58846577373 84747.7889533154 82101.81703963532 103191.7592942972 84157.65325129467 69239.66496873372 77169.92378100863 0.9399601112970335 1.0201551267239561 1.0115018063773686 0.9699321289752793 1.0981971317454076 1.0639095261078957 1.3372017780804455 1.090549907631316 0.8972364047581639 1.0 16.23575106037881 -6.268328696199278 22.733330725061833 1.0976472910365438 0.9897360299610302 0.15295092960190226 0.10608661161515223 280.8064199411165 926603.0134261725 0.0340052682064148 0.03951938546636808 5.391024478610925e-07 6.268328696199278 -0.10791126107551363 DGVLTLANNVT(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 1 DGVLTLANNVTPAK 14 0 E7EVA0;P27816;P27816-6 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 DGVLTLANNVT(1)PAK 117.0 0.00033374 6796000.0 24020.0 20369.0 29811.0 25839.0 24059.0 36487.0 31862.0 35822.0 30858.0 25441.0 True False 31657.860352962653 26952.880912495184 29415.68666183863 19882.21775857047 20718.8231385694 34205.4621220264 34697.65627512728 30286.53300766918 32489.090882144435 24550.318333637733 1.2895091592187824 1.097862787203275 1.198179439552708 0.8098558026161623 0.8439329729660332 1.3932797798047134 1.4133281615165911 1.2336513358432484 1.3233673975473204 1.0 14.583454111029662 -6.776915715946046 24.998527021303534 1.2961162285568788 1.0457732126518815 0.29376306791164475 0.17241043382020013 299.91753321637873 484445.9815010313 0.0631186370215226 0.05585871779406157 1.6714149563536224e-07 6.776915715946046 -0.2503430159049973 DGVLTLANNVT(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DGVLTLANNVTPAK 14 0 E7EVA0;P27816;P27816-6 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 DGVLTLANNVT(1)PAK;DGVLTLANNVT(1)PAK 170.48 0.00030247 9750100.0 64243.0 103705.0 80863.0 56139.0 63191.0 38782.0 52401.0 34065.0 39937.0 32349.0 True False 75118.0710429124 114000.14703753176 82791.08059463513 52993.71383509371 50809.17717038902 36748.20364819086 47437.19792961337 33170.829844850974 40521.00307161895 38213.61762545689 1.9657408984191735 2.983233572777153 2.166533443813022 1.3867756346572828 1.3296091898020486 0.9616520479262394 1.241368938019937 0.8680368911932969 1.060381235526493 1.0 15.22179922147034 -5.78769614521536 2.242830840716415 1.0771293831817361 2.5084753873069245 0.8328041102630608 0.26189241190957807 0.10558885374510368 1.0841005168922848 0.07565301842125978 0.1397231014896118 1.6304363709220816e-06 5.78769614521536 1.4313460041251884 DGVLTLANNVT(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 2 DGVLTLANNVTPAK 14 0 E7EVA0;P27816;P27816-6 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 DGVLTLANNVT(1)PAK;DGVLTLANNVT(1)PAK 144.08 0.00042089 11759200.0 60980.0 88450.0 78959.0 73582.0 90896.0 71375.0 85897.0 73411.0 68282.0 69648.0 True False 60110.41401763762 88245.199459352 72467.29581055428 78993.46574235623 85549.67598841181 68322.4576332515 90344.3263627512 76821.94306003138 60591.36211866345 81686.5639998737 0.7358665987925573 1.0802902599684379 0.8871384994313914 0.9670313191589056 1.047291889869968 0.8363977414126164 1.1059875937845898 0.9404477223469719 0.7417543247229389 1.0 16.317811179525897 -4.739332214838564 24.98487979306284 0.9563535165502122 0.7358657262094009 0.27801743427360026 0.10654830967945025 2406.9372124032575 2720110.5490275924 0.025438703747158904 1.2911305778064244 1.8225010414420813e-05 4.739332214838564 -0.22048779034081123 DGVLTLANNVT(ph)PAKDVPPLSETEATPVPIK ddPTM_PC-9_AZD4547_30min_R2 1 DGVLTLANNVTPAKDVPPLSETEATPVPIK 30 1 E7EVA0;P27816;P27816-6 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 DGVLT(0.015)LANNVT(0.899)PAKDVPPLS(0.022)ET(0.044)EAT(0.02)PVPIK 55.852 0.0014135999999999999 3163800.0 18341.0 23081.0 19126.0 16237.0 15662.0 20037.0 18440.0 20762.0 19459.0 18726.0 True False 24173.05648350073 30541.481876444665 18872.376743293604 12493.810509149307 13487.601645798817 18784.083222491383 20081.12427698659 17553.709963297064 20487.563013664152 18070.408439750805 1.337715003183076 1.690137883616417 1.0443801979471947 0.6913961325669736 0.7463916319749114 1.0394941146526968 1.111271189245101 0.9714063753358712 1.133763139996114 1.0 14.141341494902132 -5.36422366848644 5.5629740019002485 0.9509049190137363 1.509689900376594 0.6639035416520641 0.15619049506020044 0.12646031464915167 5.553857604416804 0.04378908205250952 0.09351630646474118 4.322911369621587e-06 5.36422366848644 0.5587849813628577 DGVTVAK ddPTM_PC-9_Lapatinib_30min_R1 1 DGVTVAK 7 0 P10809;E7ESH4;E7EXB4;P10809-2;C9JL19;C9JCQ4;C9JL25 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 89.14200000000001 0.028232 0.0 29202.0 27752.0 22838.0 22002.0 29927.0 32122.0 29634.0 30205.0 36952.0 23706.0 False True 28785.574125009076 27687.74194907779 20960.347797229406 23620.10047652041 28166.752698745815 30748.21694003927 31168.303519724395 31608.434568773726 32790.076638189465 27803.55051374054 1.035320079382783 0.9958347562623155 0.7538730633294759 0.8495354024964306 1.013063158420209 1.105909726343888 1.1210188247116493 1.1368488550824762 1.179348537589995 1.0 14.76298150643682 -6.560537629742091 3.1352110918820855 1.1181567050344234 0.9047364859522007 0.5566569837378159 0.08363408732300888 0.19372974244056093 3.918608415903223 0.030839374346081118 0.03202995806211506 2.750821247877843e-07 6.560537629742091 -0.21342021908222275 DGVVEITGK ddPTM_PC-9_Lapatinib_30min_R1 2 DGVVEITGK 9 0 P04792 P04792 HSPB1 Heat shock protein beta-1 0 ; 111.46 0.010292 10066700.0 90986.0 96534.0 101492.0 88921.0 89405.0 91229.0 88829.0 80784.0 93518.0 82163.0 False True 89688.52295521091 96310.48145403131 93147.71953044932 95460.54697176008 84146.37367699294 87327.3483351859 93428.13097636492 84537.51955649116 82985.01805180231 96364.76507468439 0.9307190536468462 0.999436686006436 0.9666159561356082 0.9906167144990856 0.8732068574211541 0.9062165851543941 0.9695258521510064 0.877265870891431 0.8611551949251105 1.0 16.556218113719922 -6.249655346238252 24.8603486196453 0.9107559687876728 0.973444135872639 0.2875476570563137 0.0439014013409205 841.3631952119376 1774992.4124028066 0.01273407266166847 0.01629319110968053 5.627877733632771e-07 6.249655346238252 0.06268816708496616 DGVYVLDLAAK ddPTM_PC-9_Lapatinib_30min_R1 2 DGVYVLDLAAK 11 0 P53396;P53396-2 P53396 ACLY ATP-citrate synthase 0 ; 155.15 0.00062755 13016400.0 111009.0 102822.0 96840.0 105000.0 108580.0 87704.0 103988.0 92724.0 84106.0 103244.0 False True 109425.99130344237 102583.92197636473 88878.18901321001 112722.05026973183 102193.53787649347 83953.10436800968 109371.98982280817 97032.29554560449 74633.09660455633 121089.58783601735 0.9036779566186143 0.8471737645625363 0.7339870471239125 0.9308979598013245 0.8439498366687531 0.6933139823855139 0.9032319935791883 0.8013264994923274 0.6163461114891761 1.0 16.885715291383534 -6.55911966011973 24.999034156368374 0.7935821124138427 0.8502013962399599 0.04508550898862651 0.10910743952144308 556.9064466159153 384151.2901065659 0.03487318359655948 0.03487328885152324 2.759817345582802e-07 6.55911966011973 0.05661928382611725 DGWNQNHFITPVS(ph)TLER ddPTM_PC-9_AZD4547_30min_R2 1 DGWNQNHFITPVSTLER 17 0 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 DGWNQNHFIT(0.023)PVS(0.717)T(0.261)LER 88.765 0.0015132 4627300.0 12055.0 16448.0 17813.0 15346.0 15855.0 17472.0 16416.0 21702.0 17992.0 15452.0 True False 15888.239240423178 21764.494341829308 17576.78798119257 11808.21679333652 13653.806927221325 16379.473077974217 17876.99219799413 18348.454562348186 18943.020388604004 14911.030183222754 1.0655359854545756 1.4596237868472546 1.1787775737298964 0.7919115344976375 0.9156850170274619 1.0984803113337998 1.198910603648871 1.2305289666030637 1.270403195207657 1.0 13.864092314493696 -5.523996520390048 24.996696552410413 1.0743097327498095 1.2767351185867943 0.18227782299961504 0.16353975264502768 58.51420013448996 1308542.1883039817 0.047887952085768286 0.08381710379270893 2.9922886110217577e-06 5.523996520390048 0.20242538583698488 DGWNQNHFITPVS(ph)TLER ddPTM_PC-9_Lapatinib_30min_R1 1 DGWNQNHFITPVSTLER 17 0 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 DGWNQNHFIT(0.012)PVS(0.494)T(0.494)LER 95.59100000000001 0.0046725000000000004 0.0 25092.0 26770.0 20312.0 16066.0 21923.0 18387.0 16992.0 20261.0 19985.0 17325.0 True False 24734.18347869075 26708.015709743904 18642.025766587423 17247.547234604877 20633.53224227635 17600.63087219047 17871.762617505454 21202.400026416984 17734.078848620273 20319.60316588858 1.2172572110174436 1.3143965210196544 0.9174404447958225 0.8488131925508812 1.015449567288537 0.8661896951677399 0.8795330534558654 1.0434455758471894 0.872757145099726 1.0 14.31058460664993 -5.265364195282831 24.999223544530913 0.9280113165878667 1.265826881658125 0.7946926894030018 0.06817630377203289 119.9680582128836 764144.5177974862 0.017046219508226282 0.037719750881627725 5.427949578178765e-06 5.265364195282831 0.33781556507025834 DGWS(ph)LDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DGWSLDR 7 0 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 DGWS(1)LDR 79.986 0.026067 1683600.0 6895.7 12334.0 9710.9 9823.9 10642.0 7382.0 8857.4 7143.3 9818.7 7537.2 True False 8063.00581371684 13558.43800743373 9942.444684793329 9273.498732513523 8556.776494236205 6994.87492473171 8018.362949977234 6955.795943951974 9962.27991234457 8903.634695557632 0.9055858746922519 1.5227981011169023 1.1166725752746796 1.0415407920026671 0.9610430781156725 0.7856201611934646 0.9005718702697794 0.7812310569550309 1.1189003427235324 1.0 13.120178686672732 -5.911687646054316 2.0222561561871575 0.9055245959336998 1.2258948865358663 0.31693695992606075 0.16839336643256034 0.322841040816455 2.682005087196402 0.05063484754635824 0.08656454452723909 1.2254972864231032e-06 5.911687646054316 0.3203702906021665 DGWS(ph)LDR ddPTM_PC-9_Lapatinib_30min_R1 2 DGWSLDR 7 0 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 DGWS(1)LDR;DGWS(1)LDR 91.265 0.015373 3400100.0 17417.699999999997 21390.5 18611.0 16188.800000000001 17593.9 19517.1 24650.0 22337.0 18296.1 20200.5 True False 17169.320403985002 21340.97161147839 17080.875420537548 17379.378356253674 16559.061392938278 18682.399129582227 25926.256386623667 23374.85856522757 16235.400551525709 23692.1295095257 0.7246845580968935 0.9007620696526246 0.7209514625382231 0.7335507071775076 0.6989266788483708 0.788548750844484 1.0942982721835834 0.9866085931967167 0.6852655665670776 1.0 14.532120257095851 -7.031844618221753 22.32353560423116 0.9405696859446155 0.7589682953875228 0.3937209293640206 0.11020045052498896 194.1203730985447 136080.06597511086 0.042360888609359125 0.03286664483373711 9.292988116206066e-08 7.031844618221753 -0.1816013905570928 DGWS(ph)LDRDR ddPTM_PC-9_AZD4547_30min_R2 1 DGWSLDRDR 9 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 DGWS(1)LDRDR 134.13 0.0054667000000000006 5632500.0 24302.0 22059.0 36127.0 34951.0 29690.0 33112.0 30611.0 33656.0 30445.0 29816.0 True False 32029.530486998283 29189.140362743936 35647.932375037526 26893.586937567117 25568.055986704578 31041.501405556457 33335.31969863537 28455.23853794077 32054.260545300633 28772.150915284084 1.1132129322310709 1.0144928145513912 1.238973494890886 0.9347089488287421 0.8886390197933566 1.07887316095881 1.1585967207243892 0.988985447133361 1.114072445945397 1.0 14.812385455990615 DGWS(ph)LDRDR ddPTM_PC-9_Lapatinib_30min_R1 1 DGWSLDRDR 9 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 DGWS(1)LDRDR 66.663 0.022571 2723600.0 7371.3 12686.0 13640.0 8924.9 16980.0 13796.0 15987.0 15121.0 16347.0 8355.4 True False 7266.18391026914 12656.626346425512 12518.571851922628 9581.26691859362 15981.269783964428 13205.977240046757 16814.728635008236 15823.576861924437 14505.828718458632 9799.619757129321 0.7414761072727254 1.2915425965602072 1.2774548566351507 0.9777182335695374 1.6308050904054614 1.3476009852769315 1.7158552119101715 1.6147133515474033 1.4802440378266204 1.0 13.258510055813753 -6.261106257674925 24.99999137481876 1.5022912830564537 1.102398053309563 0.3885791686686272 0.23742495326025 30.56462233953829 2293804.2935275435 0.06912957970679336 0.08381812474381349 5.481428358643652e-07 6.261106257674925 -0.3998932297468907 DGYDYDGYR ddPTM_PC-9_AZD4547_30min_R2 2 DGYDYDGYR 9 0 J3KTL2;Q07955;Q07955-3;Q07955-2 J3KTL2 SRSF1 Serine/arginine-rich splicing factor 1 0 ; 137.14 0.0044329999999999994 58990000.0 217850.0 205636.0 247820.0 333030.0 303100.0 282030.0 232490.0 303750.0 262720.0 259100.0 False True 287121.7684385057 272103.815568848 244533.74487728847 256255.07876220925 261019.79688683647 264394.6195158575 253181.15960719102 256812.41698061235 276606.8428464898 250028.98786390186 1.1483539204453947 1.0882890735731894 0.9780215764837451 1.0249014762308137 1.0439581390815262 1.0574558645166987 1.0126072251470497 1.027130570637685 1.1062990943956268 1.0 17.931735842216582 -4.98450824759355 4.405777458859525 1.0325222810866697 1.1405514340584268 0.5584052187688705 0.032970423297322964 0.1389136749331321 6.680141631460086 0.008339494693213908 0.0339769583982535 1.036314923809261e-05 4.98450824759355 0.10802915297175719 DGYDYDGYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DGYDYDGYR 9 0 J3KTL2;Q07955;Q07955-3;Q07955-2 J3KTL2 SRSF1 Serine/arginine-rich splicing factor 1 0 ;; 128.38 0.006136600000000001 83452000.0 291642.0 276977.0 288911.0 314787.0 355320.0 348910.0 309859.0 310782.0 304216.0 246582.0 False True 341011.23040793615 304473.44608277705 295799.7339410684 297150.50494322425 285697.59668596194 330612.545379049 280506.9123351098 302624.3018007472 308664.5834798724 291285.36465796153 1.1707118577974718 1.0452754687496966 1.0154980985344315 1.0201353758097313 0.9808168598564471 1.1350125529556454 0.9629969314266502 1.0389272463314465 1.0596638929742255 1.0 18.152073690965516 -4.7629711860809705 3.8859553480272284 1.0278112116420952 1.1873458641274073 0.4793989615332612 0.04475291389987401 0.22050663143188018 6.011876450079216 0.01074851032246354 0.10322232396590293 1.7259523990931742e-05 4.7629711860809705 0.15953465248531207 DGYDYDGYR ddPTM_PC-9_Lapatinib_30min_R1 3 DGYDYDGYR 9 0 J3KTL2;Q07955;Q07955-3;Q07955-2 J3KTL2 SRSF1 Serine/arginine-rich splicing factor 1 0 ;; 140.14 0.0036474000000000003 104503000.0 344099.0 297644.0 361653.0 317438.0 316245.0 280037.0 302142.0 281398.0 334808.0 259650.0 False True 339192.0851599715 296954.8236051934 331919.28636095085 340783.449462125 297644.090861592 268060.47030813113 317785.43436784 294472.77837390406 297098.3973554595 304530.1565381229 1.1138210054987097 0.9751245229075328 1.0899389739728427 1.1190466433148263 0.9773879022202226 0.8802427758072416 1.043526979332366 0.9669741142271412 0.975595982784933 1.0 18.216225574600514 -6.334601880738451 8.389533400854766 0.9708210480783747 1.0683898152400106 0.4603297776277674 0.053107857756082656 0.3362086072208532 35.85272781137316 0.016556690683071335 0.018784376625449215 4.6280508202844866e-07 6.334601880738451 0.09756876716163598 DGYGGSRDS(ph)YSSSR ddPTM_PC-9_AZD4547_30min_R2 2 DGYGGSRDSYSSSR 14 1 P38159;P38159-2;H3BUY5;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 DGYGGSRDS(0.9)Y(0.023)S(0.051)S(0.015)S(0.011)R;DGYGGSRDS(1)YSSSR 140.49 0.00057537 25096400.0 18117.4 19652.6 27319.0 41693.0 40129.0 38065.0 27626.7 39771.0 29543.6 31019.0 True False 23878.356334669686 26004.91862246074 26956.7322100825 32081.323000428773 34557.78102696085 35684.78953257147 30085.42277999052 33625.305796661596 31105.21438154522 29933.034251448775 0.7977258881970498 0.8687698815966874 0.9005679806342313 1.071769828976694 1.154503106389498 1.192154100810689 1.0050909816646594 1.1233510613790887 1.0391600838140793 1.0 14.869450908891354 -5.685054051792414 2.7422162300293493 1.095624247915944 0.838629150811396 0.7524418883832775 0.06061144176355118 0.125966157287981 1.9115070884792316 0.017675985006367422 0.03360630683319647 2.0651231169642165e-06 5.685054051792414 -0.25699509710454793 DGYGGSRDS(ph)YSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DGYGGSRDSYSSSR 14 1 P38159;P38159-2;H3BUY5;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 DGYGGS(0.013)RDS(0.986)YS(0.001)SSR 123.63 0.00019612 12479000.0 28468.0 27955.0 35433.0 39341.0 44036.0 34301.0 39423.0 31106.0 33925.0 32864.0 True False 33287.0701313704 30730.187651841243 36277.857100400826 37136.85131524287 35407.46191507099 32502.19517654053 35688.56804219666 30289.50045953132 34421.08894520551 38821.983048719136 0.8574283825119708 0.7915666650329737 0.9344668729280111 0.9565933628026798 0.9120467099951299 0.8372111011370111 0.9192876107696447 0.7802151791555807 0.8866391215000331 1.0 15.244586193156993 -5.258682387918185 24.999429451938017 0.895883351403631 0.8244975236037574 0.2091950511085735 0.05991626185475292 397.94859096845147 3608409.4056597203 0.015679269723750718 0.0377547803041986 5.512106652952268e-06 5.258682387918185 -0.07138582779987357 DGYGGSRDS(ph)YSSSR ddPTM_PC-9_Lapatinib_30min_R1 2 DGYGGSRDSYSSSR 14 1 P38159;P38159-2;H3BUY5;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 DGYGGSRDS(0.975)YS(0.011)S(0.003)S(0.011)R;DGYGGSRDS(1)YSSSR 155.63 0.0016041 31732000.0 54248.0 44280.0 51998.0 40068.0 53051.0 49728.0 43704.0 46358.0 50294.0 35834.0 True False 53474.4135721352 44177.47238055507 47722.9251580845 43014.734382929724 49930.64448227901 47601.249361629845 45966.779274685636 48511.9619181994 44629.36010070094 42027.859154196376 1.2723563523886017 1.0511473405883454 1.1355069260842778 1.023481453697477 1.1880368281212714 1.1326118036844373 1.0937216455884113 1.1542810624784252 1.0618994400109674 1.0 15.359058348856676 -14.522878743649104 0.18096034039858103 0.4965045719812839 1.145979222904195 0.2708971421421469 0.06678962070137784 193.47518964457706 1.8602126997050419 34.92472989666506 0.19686019335434465 3.000000011268165e-15 14.522878743649104 0.649474650922911 DGYNYTLSK ddPTM_PC-9_AZD4547_30min_R2 1 DGYNYTLSK 9 0 P31949 P31949 S100A11 Protein S100-A11;Protein S100-A11, N-terminally processed 0 99.568 0.018887 13604000.0 35936.0 34265.0 51517.0 59097.0 47926.0 51045.0 39629.0 56094.0 52360.0 48726.0 False True 47362.90048476544 45340.4911614045 50833.85091939014 45473.09968954831 41272.30216297757 47853.14808065441 43155.90422845451 47425.9612118864 55127.6427049414 47020.117571040115 1.0072901330628838 0.9642785578513715 1.0811085455621856 0.9670988087353355 0.8777583786476397 1.017716470154625 0.9178178715366379 1.0086312766069359 1.1724267303596607 1.0 15.520990525919041 -8.016335513107727 23.676578991903728 1.0876519672676683 0.9762005747461633 0.31087032782602886 0.06472234777157361 406.3367924345106 588935.886629085 0.04034696271233895 0.016209191220282526 9.630847074870734e-09 8.016335513107727 -0.11145139252150504 DGYNYTLSK ddPTM_PC-9_Lapatinib_30min_R1 2 DGYNYTLSK 9 0 P31949 P31949 S100A11 Protein S100-A11;Protein S100-A11, N-terminally processed 0 ; 145.25 0.0023209 61698000.0 213973.0 228698.0 254150.0 242180.0 242948.0 229170.0 248600.0 205140.0 239795.0 214631.0 False True 210921.70578215728 228168.4638321638 233254.7680473704 259990.72508879667 228658.27629414544 219368.9333213626 261471.29159085822 214671.55330038903 212786.76194670517 251729.68237216887 0.8378896910151454 0.9064027002379041 0.926608121256498 1.0328171181037533 0.9083484877086779 0.8714464311643526 1.0386986910994744 0.8527860174351971 0.8452986550553515 1.0 17.941515814441246 -4.795419186352754 2.5212945099270803 0.9328642490178138 0.8192113232265894 0.16199506598537783 0.0664789481361111 0.9813402854126299 8.17389022521103 0.017538090730115512 0.24053818281746822 1.6016986651832217e-05 4.795419186352754 -0.11365292579122444 DGYQQNFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DGYQQNFK 8 0 G3V153;Q14444-2;Q14444 G3V153 CAPRIN1 Caprin-1 0 90.65700000000001 0.0429 2130900.0 10060.0 13916.0 15451.0 17614.0 19008.0 15482.0 17349.0 15456.0 15280.0 15113.0 False True 11762.95930594304 15297.488512359962 15819.410438243798 16627.14468535848 15283.518850069713 14670.096665496652 15705.57712411714 15050.29637698567 15503.441093080048 17852.867265557834 0.6588834796658358 0.8568645184447337 0.88609914603258 0.931343096771685 0.8560820300028238 0.8217221607757396 0.8797229537698241 0.8430184436547653 0.8684006250911666 1.0 14.123868176918908 -14.522876794390228 0.01997133060444367 2.0813451219126295 3.017403142114062e-11 0.4075857995430159 0.06349627083650343 4042.049738593078 6.088801591386695 427.82834447218875 233.7755192702484 3.000013476301719e-15 14.522876794390228 -2.0813451218824555 DGYQQNFK ddPTM_PC-9_Lapatinib_30min_R1 2 DGYQQNFK 8 0 G3V153;Q14444-2;Q14444 G3V153 CAPRIN1 Caprin-1 0 ; 101.54 0.020983 13808300.0 63538.0 46576.0 58698.0 52975.0 57123.0 56254.0 52802.0 45922.0 55016.0 51123.0 False True 62631.93646855788 46468.15613362089 53872.07702083247 56870.95821941953 53763.13744813902 53848.147554478826 55535.82919782977 48055.703766503124 48819.51873583656 59959.54243288444 1.0445699537928392 0.7749918403002308 0.8984737847380013 0.9484888628541136 0.8966569000808946 0.8980746911928759 0.9262216979056113 0.8014688207518287 0.8142076599480819 1.0 15.87170175329007 -7.7321066561601635 24.974729515250143 0.855878538717225 0.9068892063051026 0.03710229179160607 0.08011134947666891 525.8934236275039 447761.18661792466 0.03587683739596729 0.020709225844746496 1.853076479955681e-08 7.7321066561601635 0.051010667587877645 DGYRDGYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DGYRDGYR 8 1 E7EX17;P23588-2;P23588;F8VX11 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 ; 83.75299999999999 0.018938 4133900.0 8419.4 1649.54 7462.6 12216.7 12184.3 24850.0 9561.4 22276.2 17763.5 13039.8 False True 9844.638129270063 1813.2954297699218 7640.536686068106 11532.237906075796 9796.873880729396 23546.822254075163 8655.674973458614 21691.473353584894 18023.257582259645 15403.81251699999 0.6391039957416582 0.11771731366950414 0.49601594914478736 0.7486612741714794 0.6360031888155837 1.5286359937248242 0.5619177047179729 1.4081886110757127 1.1700517363716791 1.0 13.910999848562994 -6.227077606766314 1.291968592563398 1.1229494852000488 0.3757038444461715 0.5084212555297368 0.29232678805701995 0.3429351904656858 1.162971943401527 0.11008593676532753 0.16246633900567342 5.928193805537354e-07 6.227077606766314 -0.7472456407538772 DHAGVMGESNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DHAGVMGESNR 11 0 P52306-6;P52306-2;P52306-3;P52306-4;P52306;P52306-5 P52306-6 RAP1GDS1 Rap1 GTPase-GDP dissociation stimulator 1 0 67.87899999999999 0.026194 748880.0 2161.1 2892.7 3656.9 3252.1 3298.2 3994.6 2886.2 3283.0 2248.7 2980.1 False True 2526.931546329372 3179.8681388117006 3744.094364870478 3069.8953804504554 2651.9413863268032 3785.116143908598 2612.798241721534 3196.8247286260325 2281.5829833775583 3520.3685395413777 0.7178031271290057 0.9032770583803603 1.0635518193098745 0.8720380681649857 0.7533135683209717 1.0752045137869886 0.7421945209355612 0.9080937670924945 0.6481091277093379 1.0 11.781510753961312 DHAGVMGESNR ddPTM_PC-9_Lapatinib_30min_R1 1 DHAGVMGESNR 11 0 P52306-6;P52306-2;P52306-3;P52306-4;P52306;P52306-5 P52306-6 RAP1GDS1 Rap1 GTPase-GDP dissociation stimulator 1 0 67.252 0.027256 523540.0 2646.2 4212.5 4641.2 2395.0 3441.1 3156.9 2917.1 3653.3 2636.4 2725.9 False True 2608.4647027463516 4202.746215065231 4259.618451550098 2571.1362894857916 3238.701263462899 3021.8867460933297 3068.133164520079 3823.045655027352 2339.460869477233 3197.0681829665655 0.8158927346760407 1.3145625850135905 1.3323514569519097 0.8042169082237182 1.0130222685641013 0.9452055987399416 0.9596708574645263 1.1957973481441178 0.7317519475941995 1.0 11.642533797056656 -5.762323207610823 24.99999080926737 0.9609454633166111 1.1702982702400684 0.2175900229079526 0.17590121955953358 34.428001056779735 973883.8921955973 0.04755112804647201 0.07541878020839032 1.7285294862601106e-06 5.762323207610823 0.20935280692345726 DHALLEEQSK ddPTM_PC-9_AZD4547_30min_R2 2 DHALLEEQSK 10 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ; 157.75 0.00033079 9691700.0 153714.0 114111.0 153497.0 217761.0 204500.0 169462.0 155845.0 197476.0 152212.0 163703.0 False True 202591.85455017918 150995.14918777274 151461.52948684184 167559.5658239122 176108.7049269476 158865.51435094237 169714.90308823038 166960.62174704036 160257.61557304306 157971.80779731506 1.2824557582458869 0.9558360526044388 0.9587883534331252 1.0606928423513307 1.114810974075216 1.0056573800483055 1.0743366519295787 1.0569013805378384 1.0144697196772021 1.0 17.26930758739558 -4.750701599211195 24.993834338850387 1.0311146154688424 1.2824562905794692 0.7164959608769479 0.048170809384163134 271.74068020839275 632476.8198539513 0.01280884913630765 0.18334177667482812 1.7754089333230297e-05 4.750701599211195 0.25134167511062677 DHALLEEQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DHALLEEQSK 10 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ; 150.15 0.00012821 8342800.0 113143.0 130269.0 122149.0 140066.0 164847.0 139096.0 138863.0 127548.0 117365.0 110689.0 False True 132295.87522388788 143201.2454021718 125061.4954126619 132218.5561200991 132546.41371409103 131801.5608954866 125708.89135894153 124200.00014827715 119081.2410922341 130756.0394863581 1.0117764024023566 1.0951788228268577 0.9564490933186278 1.011185079018041 1.013692478257723 1.0079959703065002 0.9614002676492572 0.9498605237369173 0.9107131231567926 1.0 16.996518059041264 -7.277891151395713 2.3561043423108106 0.9478261830933127 1.018247617866201 0.3874555818236367 0.03735364739418743 0.30982159915688245 3.376452900700793 0.018001447959125467 0.011690476663800542 5.273620192770999e-08 7.277891151395713 0.07042143477288831 DHALLEEQSK ddPTM_PC-9_Lapatinib_30min_R1 3 DHALLEEQSK 10 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ;; 144.55 0.00010829 15500000.0 260259.0 232260.0 246273.0 253780.0 245407.0 232314.0 217703.0 204191.0 237996.0 222741.0 False True 256547.65893434462 231722.2162400118 226025.3845812714 272443.8277852628 230972.64274872563 222378.4717703845 228974.59611104004 213678.45929589373 211190.384271015 261241.48506627357 0.982032615797073 0.8870039005528807 0.865197135607814 1.042881178370837 0.8841346262065953 0.8512372057369447 0.8764863515186042 0.8179346371487908 0.8084105945785707 1.0 17.995024489035657 -6.508215771766901 24.693892114309833 0.8606666086384016 0.9381600835744871 0.20534987639433733 0.06718745259582717 868.0248714534797 1461842.379628923 0.020758110367682023 0.02270055670112847 3.1030175240336855e-07 6.508215771766901 0.0774934749360855 DHANYEEDENGDIT(ph)PIK ddPTM_PC-9_AZD4547_30min_R2 2 DHANYEEDENGDITPIK 17 0 H3BSB3;H3BNT4;Q99547 H3BSB3 MPHOSPH6 M-phase phosphoprotein 6 1 DHANYEEDENGDIT(1)PIK;DHANYEEDENGDIT(1)PIK 112.14 0.00058625 31231000.0 149140.0 168587.0 194121.0 173914.0 213641.0 213939.0 171267.0 224710.0 190198.0 214861.0 True False 196563.4176952894 223079.45085153045 191546.82870359172 133820.81424451526 183980.63486209366 200561.36050988585 186509.43121185762 189986.23282210212 200251.47798308736 207338.781788599 0.9480301562478741 1.0759176306870584 0.9238350252240382 0.645421049984551 0.8873430878439272 0.9673123319224314 0.8995395342971638 0.9163082332364169 0.9658177609399778 1.0 17.661630465756964 -10.605365724010698 12.135999300041098 0.9999999932995556 0.911889984295804 0.05805040461811317 0.10301165183592176 0.0 0.0 0.10783898674317204 0.026154796247908476 2.481042912659632e-11 10.605365724010698 -0.08811000900375154 DHANYEEDENGDIT(ph)PIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DHANYEEDENGDITPIK 17 0 H3BSB3;H3BNT4;Q99547 H3BSB3 MPHOSPH6 M-phase phosphoprotein 6 1 DHANYEEDENGDIT(1)PIK;DHANYEEDENGDIT(1)PIK 102.43 0.0020212 14851600.0 86851.0 106562.0 95807.0 114699.0 124920.0 100150.0 120484.0 99432.0 91703.0 78690.0 True False 101553.15891455839 117140.77111627634 98091.40223007063 108272.78688917546 100442.82274572343 94897.95769600105 109070.88329137853 96822.01535691236 93043.98288996861 92955.87409030295 1.0924878057292378 1.26017610250729 1.055246945822689 1.1647761687872757 1.0805430396808189 1.0208925323407905 1.1733619242332172 1.041591145308941 1.0009478561793745 1.0 16.504258414712304 -6.833379350956304 0.28246169576265723 0.9852748713708142 1.199843982180065 0.35389998911749143 0.06527338503999111 2.9215634671321804 0.5162781666832578 0.09992404619996946 0.21769360026883167 1.4676437485958395e-07 6.833379350956304 0.2145691108092509 DHANYEEDENGDIT(ph)PIK ddPTM_PC-9_Lapatinib_30min_R1 2 DHANYEEDENGDITPIK 17 0 H3BSB3;H3BNT4;Q99547 H3BSB3 MPHOSPH6 M-phase phosphoprotein 6 1 DHANYEEDENGDIT(1)PIK;DHANYEEDENGDIT(1)PIK 100.76 0.0023655 34019000.0 135355.0 191419.0 212650.0 184866.0 232260.0 200471.0 195127.0 202043.0 209296.0 188463.0 True False 133424.81287893327 190975.78106624863 195166.73785273798 198461.66233489796 218598.9234407293 191897.322650726 205229.7212962562 211430.65537423428 185722.88049541297 221038.57843883717 0.6036268140217559 0.8639929844603705 0.8829532800616609 0.8978598384797956 0.9889627638064866 0.8681621281048243 0.9284791946535461 0.9565328227657713 0.8402283520240957 1.0 17.75393866335279 -4.331029824964989 1.4506104409402358 0.921893713813284 1.6698654164714785e-15 0.7934770144847987 0.04832419638621679 1.578008242639979 1.260709282193083 0.012906858778529392 2.9052047471321703 4.6662733380584554e-05 4.331029824964989 -0.9218937138132823 DHAPSIPT(ph)SPFGDSLESSTELR ddPTM_PC-9_AZD4547_30min_R2 1 DHAPSIPTSPFGDSLESSTELR 22 0 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;J3QL92 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 DHAPSIPT(0.582)S(0.417)PFGDSLESSTELR 95.319 0.00034773 4330200.0 12443.0 14092.0 17534.0 19552.0 19314.0 19359.0 15958.0 22939.0 23055.0 16533.0 True False 16399.615169521825 18646.963415920378 17301.487703487917 15044.58847538876 16632.58448390745 18148.478669671647 17378.231085257703 19394.304635780347 24273.64023228464 15954.184702253553 1.027919350037696 1.168781969365471 1.084448251438637 0.9429869815449541 1.0425217455053075 1.1375372047127013 1.089258486696785 1.2156249283638336 1.5214591460042426 1.0 13.961647264815428 -7.839046140329544 3.796876524050466 1.2904376814724057 1.0703666593978196 0.2683112295743352 0.13122106280545753 0.25373177846928724 7.046171035401955 0.07457490626449556 0.033845441778329904 1.448617941250921e-08 7.839046140329544 -0.22007102207458606 DHAPSIPT(ph)SPFGDSLESSTELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DHAPSIPTSPFGDSLESSTELR 22 0 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;J3QL92 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 DHAPSIPT(0.562)S(0.438)PFGDSLESSTELR 134.56 5.171e-05 3161700.0 5925.8 9307.6 12185.0 9543.8 11320.0 11223.0 11760.0 8832.2 9783.3 6373.7 True False 6928.920900115034 10231.597016214546 12475.536611869835 9009.091827417069 9101.927261299927 10634.446123037655 10646.007664973054 8600.364108489443 9926.362254314792 7529.2013558185645 0.9202730240120841 1.3589219536953372 1.6569535097143795 1.1965534459315323 1.2088834965565054 1.412426845885767 1.413962406085185 1.1422677787522688 1.318381828989565 1.0 12.878281126835994 -9.340096455514619 0.8114399842497468 0.9954592724178789 1.3116339633977132 0.17622279306914512 0.18625852336657908 6.412488592911406 4.994081924745061 0.2708472991649593 0.06351262449414008 4.5698668295804925e-10 9.340096455514619 0.3161746909798343 DHAPSIPT(ph)SPFGDSLESSTELRR ddPTM_PC-9_AZD4547_30min_R2 4 DHAPSIPTSPFGDSLESSTELRR 23 1 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;J3QL92 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 DHAPSIPT(0.424)S(0.424)PFGDS(0.005)LES(0.049)S(0.049)T(0.049)ELRR;DHAPSIPT(0.563)S(0.436)PFGDS(0.001)LESSTELRR;DHAPS(0.007)IPT(0.446)S(0.446)PFGDS(0.067)LES(0.021)S(0.007)T(0.007)ELRR;DHAPSIPT(0.5)S(0.5)PFGDSLESSTELRR 91.54700000000001 1.4482000000000001e-05 29109100.0 46408.4 40450.9 69658.4 99939.0 80016.0 65370.0 59111.9 76743.2 58560.3 62462.600000000006 True False 61165.305845313545 53525.86236453688 68734.68410201005 76899.60759215812 68907.15957669752 61282.403566115754 64372.7445850761 64884.30182329733 61655.67790477812 60275.8033861358 1.0147572061956514 0.8880157435918724 1.140336258343757 1.2757956472106684 1.1431976963503574 1.016699904828004 1.067969914439708 1.0764568562883983 1.0228926773452132 1.0 15.879291354468414 -10.438496752284301 14.795319885357138 0.9999966947532566 1.07490699220099 0.04618543137666331 0.09694909773886529 0.0 0.0 0.10368662221089983 0.025147699725826724 3.6433697462185195e-11 10.438496752284301 0.07491029744773336 DHAPSIPT(ph)SPFGDSLESSTELRR ddPTM_PC-9_Lapatinib_30min_R1 3 DHAPSIPTSPFGDSLESSTELRR 23 1 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;J3QL92 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 DHAPSIPT(0.5)S(0.5)PFGDSLESSTELRR;DHAPSIPT(0.741)S(0.259)PFGDSLESSTELRR;DHAPS(0.001)IPT(0.499)S(0.499)PFGDSLESSTELRR 100.45 1.4604000000000001e-05 19576200.0 63932.0 48815.2 62110.0 50786.3 65623.0 69844.0 55541.0 65049.0 81790.0 67778.0 True False 63020.31795630706 48702.171403596956 57003.55555153334 54521.29392013034 61763.18415978192 66856.93493431607 58416.641215799835 68071.41401304961 72577.94891311746 79493.33699149199 0.7927748455578358 0.6126572772861385 0.7170859559919383 0.6858599221462504 0.7769605164064545 0.841038223637179 0.7348621082802456 0.8563159704861195 0.9130066954024755 1.0 16.27854632054794 -7.962039964623773 0.44514863225471374 1.0104791359505982 0.6849626994049057 0.7378631904638311 0.055373389622283546 0.4842435385896496 0.2542483862228518 0.0623335579370375 0.04346382178815788 1.0913399046050587e-08 7.962039964623773 -0.3255164365456925 DHAPSIPTS(ph)PFGDSLESSTELRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DHAPSIPTSPFGDSLESSTELRR 23 1 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;J3QL92 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 DHAPSIPT(0.453)S(0.545)PFGDSLESSTELRR 60.938 0.0017242999999999998 7009600.0 7165.9 5896.2 8256.3 12157.0 10901.0 11372.0 10073.0 10088.0 10120.0 9500.9 True False 8378.945337023575 6481.535769371717 8453.161504192116 11475.882703525782 8765.027303483266 10775.63230073814 9118.81251779537 9823.200689119523 10267.985854840968 11223.337960916975 0.7465644682715225 0.5775051764405889 0.7531771326523853 1.0225017497903246 0.780964391699307 0.9601094022350676 0.8124866728196021 0.8752476957681262 0.9148780773239807 1.0 13.45421419484303 -5.5487121198926594 7.769129783129835 0.8966769927732683 0.6625291759251613 0.6097541521452338 0.08130846958347082 0.1090865500403584 25.99599987888743 0.020373769633207195 0.035964018889537125 2.826753119464027e-06 5.5487121198926594 -0.23414781684810704 DHFEEAMR ddPTM_PC-9_AZD4547_30min_R2 2 DHFEEAMR 8 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 ; 151.04 0.00038381 8488000.0 61865.0 54127.0 78360.0 104295.0 82768.0 77157.0 65973.0 89116.0 71100.0 72051.0 False True 81536.78312806138 71622.49423882503 77320.89520048555 80251.39909168736 71277.09187967534 72332.36059279177 71844.46919336433 75345.16988195649 74858.20084647313 69528.5164206175 1.1727099516232886 1.030116820061856 1.1120745728662975 1.154222802715954 1.0251490402654317 1.0403265353054885 1.0333093943603848 1.0836585297772032 1.0766546548126146 1.0 16.08531718559818 -6.2738880033529725 24.971740213506045 1.0467294453570781 1.1106831325643205 0.42674969828858234 0.041672081618293756 834.6014434776677 1674195.0184786054 0.012898753680062035 0.01472718982118849 5.322454980026887e-07 6.2738880033529725 0.06395368720724237 DHFEEAMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DHFEEAMR 8 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 ; 87.696 0.0078245 76029000.0 478930.0 518840.0 481530.0 567630.0 574480.0 475090.0 523360.0 497150.0 475920.0 418340.0 False True 560003.3897013218 570347.0063058959 493011.5014126933 535827.531381291 461914.76793918613 450175.4440518545 473783.5520017257 484100.33927396534 482879.4296478171 494181.7304223826 1.1331932267562395 1.154124021983601 0.9976319864987945 1.0842722391281305 0.9347062821290104 0.9109512074982711 0.9587233255199007 0.9795998303300274 0.9771292622151262 1.0 18.9146821505907 -5.504034222713803 1.0856613655695129 0.9598670667446457 1.1632359328172939 0.7048627494775546 0.042686761927054735 0.3768908913969521 0.7446677616470818 0.015276391113277572 0.06695307945089876 3.133038828901753e-06 5.504034222713803 0.20336886607264815 DHFEEAMR ddPTM_PC-9_Lapatinib_30min_R1 2 DHFEEAMR 8 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 ; 184.38 0.00078856 19657500.0 171927.0 157829.0 152242.0 139071.0 153310.0 157541.0 122022.0 133403.0 163413.0 128873.0 False True 169475.2894524494 157463.5566474851 139725.25043111463 149298.74526725576 144292.60721905704 150803.33867600784 128339.70210176865 139601.39039159485 145007.70712482271 151148.52633752188 1.121250028425702 1.0417802969237122 0.9244235045937628 0.9877618319206403 0.9546411778891232 0.9977162353489096 0.8490966151742688 0.9236040454662342 0.9593722852514855 1.0 17.205607387534663 -5.000335483773577 2.593178522198169 0.9462997415279155 1.1258244363840433 0.6245955921844843 0.04282486670274444 0.21163930513327872 2.501209639577186 0.011605002951730873 0.06746554247547952 9.992278183498335e-06 5.000335483773577 0.17952469485612776 DHFGLEGDEESTMLEDS(ph)VSPK ddPTM_PC-9_Lapatinib_30min_R1 1 DHFGLEGDEESTMLEDSVSPK 21 0 Q9Y490 Q9Y490 TLN1 Talin-1 1 DHFGLEGDEESTMLEDS(0.604)VS(0.396)PK 112.37 1.1650999999999999e-05 4911100.0 18297.0 17980.0 14829.0 16171.0 19098.0 12869.0 15049.0 15867.0 15044.0 17049.0 True False 18036.081424741154 17938.368414687902 13609.816861595358 17360.26928487461 17974.69318811266 12318.622869104214 15828.163584677473 16604.23874533133 13349.586299656907 19995.896933635468 0.9019891172974756 0.8971024642817318 0.6806304766805451 0.8681915766265318 0.898919075636817 0.6160575297016475 0.7915705725634457 0.8303822929493617 0.6676162786777182 1.0 14.287416375510478 DHFGLEGDEESTMLEDS(ph)VSPKK ddPTM_PC-9_AZD4547_30min_R2 1 DHFGLEGDEESTMLEDSVSPKK 22 1 Q9Y490 Q9Y490 TLN1 Talin-1 1 DHFGLEGDEES(0.003)T(0.043)MLEDS(0.477)VS(0.477)PKK 58.848 0.0031921999999999996 5191600.0 32929.0 26209.0 26120.0 27526.0 29903.0 32420.0 25443.0 25775.0 27341.0 28653.0 True False 43399.73703425094 34680.54670507076 25773.631733495185 21180.30597246065 25751.484613352193 30392.772274949875 27707.37771037797 21792.066000577106 28786.18944224223 27649.86719129445 1.5696182818525555 1.2542753448012913 0.9321430571503796 0.7660183618939501 0.9313420724660855 1.09920138366954 1.0020799564310974 0.7881436048068372 1.0410968430005896 1.0 14.7549849304282 -4.9764632607805295 2.4200478451070366 0.9378188857622377 1.5986932250283854 0.7996413293896061 0.09957431780387777 0.16284020446168068 1.5860086851846042 0.02815674344082969 0.19036593102880564 1.0556908057913627e-05 4.9764632607805295 0.6608743392661477 DHFGLEGDEESTMLEDSVS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 DHFGLEGDEESTMLEDSVSPK 21 0 Q9Y490 Q9Y490 TLN1 Talin-1 1 DHFGLEGDEESTMLEDS(0.068)VS(0.932)PK 167.28 1.3539000000000001e-08 6211200.0 23547.0 27211.0 20188.0 23249.0 22080.0 23592.0 24872.0 19146.0 21449.0 23258.0 True False 31034.45619197383 36006.42360989283 19920.29392939512 17889.30224346936 19014.57312854285 22116.788510506394 27085.55981655153 16187.42563131132 22582.750350998635 22443.74449918424 1.3827664181929107 1.6042966275614816 0.8875655276738319 0.7970729770212622 0.847210372103192 0.9854321996630407 1.2068200035665175 0.7212444265661501 1.0061935231805659 1.0 14.454025773844258 -5.265922219313209 24.997679003469415 0.9254427385536002 1.493531543900174 0.7318433696119828 0.13605879946946983 167.4858045086043 933956.9856907297 0.035840644634770234 0.07886181196094194 5.4209796963837604e-06 5.265922219313209 0.5680888053465738 DHFGLEGDEESTMLEDSVS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 DHFGLEGDEESTMLEDSVSPK 21 0 Q9Y490 Q9Y490 TLN1 Talin-1 1 DHFGLEGDEESTMLEDS(0.286)VS(0.714)PK 146.39 9.7869e-05 5669600.0 21228.0 23665.0 17940.0 20783.0 20670.0 18678.0 20360.0 20112.0 17419.0 20727.0 True False 20925.28482726156 23610.205146473254 16465.042450402645 22311.451150055607 19454.23123878355 17879.18548054461 21414.14117775489 21046.476942465735 15457.08878979818 24309.634333008522 0.8607815543670451 0.9712283131472053 0.6773052290649144 0.9178028284761278 0.8002683616004819 0.7354773517209015 0.8808911267199925 0.8657669076448448 0.6358420936348669 1.0 14.56924057197315 -5.226264750464875 24.99519500510864 0.8121523735015895 0.9160049210354687 0.12545911357603123 0.10744156990294232 1189.7785177207 845456.6743295172 0.02548855363808055 0.06743075925960283 5.939299822956482e-06 5.226264750464875 0.10385254753387918 DHGGALGPEEFK ddPTM_PC-9_Lapatinib_30min_R1 1 DHGGALGPEEFK 12 0 O43707;O43707-2;F5GXS2;O43707-3 O43707 ACTN4 Alpha-actinin-4 0 98.40700000000001 0.0030785 7746800.0 29478.0 34698.0 28731.0 32376.0 32533.0 29721.0 35884.0 34826.0 27918.0 39808.0 False True 29057.638314396878 34617.65891283878 26368.848084867222 34757.03904316993 30619.472902338908 28449.9021130349 37741.89793823953 36444.14309856363 24773.580850426875 46688.75975917423 0.6223690340947025 0.741455954096885 0.5647793649024015 0.7444412578627183 0.6558210811398187 0.6093522779311901 0.8083722534699229 0.7805763804081869 0.5306112430103463 1.0 15.510787644868596 -11.717468667908776 2.471753766680106 1.9723840623079967 0.6787686800843061 0.5486920573097636 0.08881149727434376 3788174.9933246598 1333452.7906212262 20481717.80816531 0.02135820440840662 1.916599330434908e-12 11.717468667908776 -1.2936153822236904 DHGS(ph)WSLSPPPER ddPTM_PC-9_AZD4547_30min_R2 1 DHGSWSLSPPPER 13 0 Q8N1F8 Q8N1F8 STK11IP Serine/threonine-protein kinase 11-interacting protein 1 DHGS(0.876)WS(0.124)LSPPPER 83.292 0.016443 0.0 5813.2 6102.6 12467.0 16053.0 12297.0 9454.9 6612.4 13694.0 7247.2 10645.0 True False 7661.676677928501 8075.146107152694 12301.679434206913 12352.228866377645 10589.773811670806 8863.68360834126 7200.890790083848 11577.906956814855 7630.272196547966 10272.32179008583 0.7458563735146077 0.7861071987587357 1.1975558871295957 1.2024768225523468 1.0309036290015134 0.8628705164684292 0.7009993395099513 1.127097378120406 0.7427991794330472 1.0 13.326474681601422 -6.763315121499655 24.996486747644425 0.8830872351332146 1.0041577648200877 0.078918397911799 0.17837300650182172 136.6454995806363 1820939.877761005 0.06531856874793181 0.060539121679635766 1.7245860884596863e-07 6.763315121499655 0.12107052968687304 DHGS(ph)WSLSPPPER ddPTM_PC-9_Lapatinib_30min_R1 1 DHGSWSLSPPPER 13 0 Q8N1F8 Q8N1F8 STK11IP Serine/threonine-protein kinase 11-interacting protein 1 DHGS(0.999)WS(0.001)LSPPPER 76.156 0.0099492 1746500.0 6534.4 5744.5 8274.7 5160.3 8166.8 8193.0 6024.1 8255.7 8208.6 7409.4 True False 6441.218257737795 5731.198963191029 7594.386107265701 5539.805676256169 7686.444880546565 7842.604488815818 6335.998421852323 8639.289960914592 7284.061027609923 8690.104917595088 0.7412129449318947 0.6595086040430785 0.8739119008665988 0.6374843259992841 0.8845054177635547 0.9024752362812889 0.7291049396910798 0.9941525496915912 0.838201735960827 1.0 13.085157879789266 -5.203638750478643 0.1396363944489656 1.073346920616552 0.4098886478216004 0.432772328399848 0.09227244819881765 22.744993758279612 0.6291834149407927 0.5955305220903659 2.9478482682897345 6.256929326143532e-06 5.203638750478643 -0.6634582727949516 DHHTADLCR ddPTM_PC-9_AZD4547_30min_R2 3 DHHTADLCR 9 0 P21980;P21980-2;A2A299;P21980-3;A2A2A0 P21980 TGM2 Protein-glutamine gamma-glutamyltransferase 2 0 ;; 116.37 0.0016135000000000001 28340300.0 52537.78 36474.950000000004 107840.2 172452.9 122960.5 136666.7 78393.6 139594.2 84458.5 124542.5 False True 69243.70118628949 48264.76428097684 106410.16848646503 132696.54827574512 105889.55702772595 128120.90964432109 85370.47853147364 118023.12394559706 88922.80388455486 120182.30498278666 0.5761555429995043 0.4015962606798867 0.8854062875704192 1.1041271699253135 0.8810744397263156 1.066054688023095 0.7103414978078594 0.9820341186042417 0.73989930462135 1.0 16.874864971211096 -5.3006299894786855 7.232027047804409 0.9241307617355788 0.48907509323635556 0.6518771381830628 0.12637237438522234 0.11931007446265743 18.884394009433823 0.03176605819290904 0.06786261325945131 5.004607362872947e-06 5.3006299894786855 -0.4350556684992233 DHHTADLCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DHHTADLCR 9 0 P21980;P21980-2;A2A299;P21980-3;A2A2A0 P21980 TGM2 Protein-glutamine gamma-glutamyltransferase 2 0 ;; 113.66 0.0017512 30216600.0 30148.7 34022.9 68360.0 63392.0 77293.0 68842.0 71046.0 59704.0 59191.0 45117.0 False True 35252.279446032284 37400.46866248719 69989.96165674379 59840.351759636935 62147.99150244303 65231.80433058528 64316.00855150303 58136.83326161697 60056.55639662966 53296.354954024486 0.6614388446722533 0.7017453387712967 1.3132222966677527 1.122785072473672 1.1660833382705873 1.2239449468327952 1.2067618621758378 1.0908219391695375 1.1268417220734286 1.0 15.701749247063454 -5.248301679780969 24.473031430064665 1.1629207343596748 0.6815919381406083 0.8497093031563064 0.0798203277284842 190.26682393432006 354428.67214775993 0.019479721039194226 0.05082971679388805 5.645446813580464e-06 5.248301679780969 -0.48132879621906655 DHHTADLCR ddPTM_PC-9_Lapatinib_30min_R1 4 DHHTADLCR 9 0 P21980;P21980-2;A2A299;P21980-3;A2A2A0 P21980 TGM2 Protein-glutamine gamma-glutamyltransferase 2 0 ;;; 116.37 0.0016135000000000001 41287400.0 57867.0 56238.5 99824.0 62669.2 80929.1 93220.0 65323.5 71040.1 111940.0 64299.0 False True 57041.805968491855 56108.28320853311 91616.85605178322 67278.10202632274 76169.0094507324 89233.19790643374 68705.63119965972 74340.88239063535 99332.13841954229 75412.99647696798 0.7563922484622806 0.7440134436995782 1.2148682631880845 0.8921287466261902 1.0100249692902112 1.1832602081219066 0.911058231463369 0.985783430755731 1.317175328656772 1.0 16.20252555472932 -5.2416950783717855 24.567003603735447 1.0544697512550625 0.7502027321017175 0.4832033962975685 0.1296098327634828 553.3126564656778 688460.3664909925 0.03205610667639754 0.0845413825409978 5.731983368736293e-06 5.2416950783717855 -0.304267019153345 DHINDIIK ddPTM_PC-9_Lapatinib_30min_R1 1 DHINDIIK 8 0 P46940;H0YLE8;A0A0J9YXZ5 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 0 82.645 0.013576 2500200.0 40968.0 43052.0 35387.0 38101.0 42230.0 37276.0 39460.0 38864.0 39293.0 38417.0 False True 40383.78880738891 42952.31573910699 32477.617457770237 40903.07464121005 39746.114427374436 35681.7923746001 41503.04572073712 40669.76332000735 34867.40856636661 45057.32726256519 0.8962757282973779 0.9532814826944452 0.720806568674425 0.9078007313406137 0.8821232159590734 0.7919198617057225 0.921116458570301 0.9026226318975838 0.7738454694212493 1.0 15.459474117015263 -11.607327538867233 2.697013232288474 1.23210882536089 0.8626190410627864 0.2583826540504852 0.07055946615907228 51050197.55504182 13085619.69904526 73063723.64158504 0.017413778740961814 2.4698607077681995e-12 11.607327538867233 -0.36948978429810364 DHLMWVLLQFISGS(ph)IQK ddPTM_PC-9_AZD4547_30min_R2 1 DHLMWVLLQFISGSIQK 17 0 Q5JWT2;Q9ULK4-6;Q9ULK4-2;Q9ULK4-4;Q9ULK4-5;Q9ULK4-3;Q9ULK4 Q5JWT2 MED23 Mediator of RNA polymerase II transcription subunit 23 1 DHLMWVLLQFIS(0.001)GS(0.999)IQK 67.749 0.018359 5467500.0 31956.0 33667.0 38033.0 45863.0 44867.0 44761.0 34832.0 44168.0 37160.0 41040.0 True False 42117.34327390816 44549.19935593186 37528.65756967925 35289.99392628653 38637.991510793996 41962.08759404787 37931.98052147489 37342.85047966981 39124.20173635642 39603.20209160382 1.0634832803794259 1.1248888221939162 0.9476167478294796 0.8910894084942763 0.9756279661786628 1.0595629994006004 0.9578008473591777 0.9429250289735229 0.9879050094449573 1.0 15.273329462756182 -5.264191755696063 24.988536010642886 0.9683782219916962 1.0941860560272179 0.5660450183186305 0.04335680349605924 164.2256963539891 1491000.5974727059 0.012016376214171249 0.02695104978728133 5.442622895812106e-06 5.264191755696063 0.12580783403552165 DHLPPPS(ph)SASPSR ddPTM_PC-9_AZD4547_30min_R2 2 DHLPPPSSASPSR 13 0 Q2YD98;Q2YD98-2 Q2YD98 UVSSA UV-stimulated scaffold protein A 1 DHLPPPS(0.25)S(0.25)AS(0.25)PS(0.25)R;DHLPPPS(0.453)S(0.265)AS(0.158)PS(0.123)R 86.49700000000001 0.012289 0.0 40485.0 38863.0 60216.0 82310.0 73435.0 59641.0 47962.0 61889.0 48345.0 68002.0 True False 53358.38785968749 51424.70474261384 59417.496495564534 63334.70117682327 63239.817830368906 55911.63884177314 52230.5250852945 52325.47711773876 50900.41800172639 65621.27067819801 0.8131264041099294 0.7836590820497349 0.9054609257254963 0.9651550560093859 0.9637091323710024 0.8520352968469599 0.7959389470135262 0.7973859173550469 0.7756694967297781 1.0 16.00187590975729 -9.811366372560478 13.003572198511076 1.0000053323436113 0.8535225038824628 0.30239331514692247 0.06807624177871537 0.0 0.0 0.0755932571555228 0.018334057872746976 1.5439514064172648e-10 9.811366372560478 -0.14648282846114857 DHLPPPS(ph)SASPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DHLPPPSSASPSR 13 0 Q2YD98;Q2YD98-2 Q2YD98 UVSSA UV-stimulated scaffold protein A 1 DHLPPPS(0.421)S(0.421)AS(0.139)PS(0.019)R 71.545 0.03827 0.0 23644.0 19676.0 25537.0 27832.0 34401.0 23592.0 25811.0 30586.0 26807.0 18976.0 True False 27646.462209713434 21629.303245846117 26145.898929611812 26272.663272561458 27660.370999644794 22354.793988657602 23365.995224542487 29783.149908545765 27199.001661138525 22416.19858606665 1.2333251823927802 0.9648961291452134 1.1663841587245507 1.1720391917339583 1.2339456618143003 0.997260704254859 1.0423709950118931 1.3286440961072778 1.2133637002147521 1.0 14.452254021384801 -7.737241479501214 24.999175702878986 1.203253195478471 1.11404586668451 0.05208944698804285 0.11526698049921319 501.6533741678892 518265.54210367636 0.053454883546163214 0.030843414211419506 1.831295889089389e-08 7.737241479501214 -0.08920732879396098 DHLPPPS(ph)SASPSR ddPTM_PC-9_Lapatinib_30min_R1 3 DHLPPPSSASPSR 13 0 Q2YD98;Q2YD98-2 Q2YD98 UVSSA UV-stimulated scaffold protein A 1 DHLPPPS(0.716)S(0.23)AS(0.047)PS(0.007)R;DHLPPPS(0.431)S(0.431)AS(0.069)PS(0.069)R;DHLPPPS(0.348)S(0.348)AS(0.259)PS(0.044)R 105.19 0.0009726000000000001 3366700.0 62537.0 56413.0 76741.0 57592.0 58256.0 63543.0 51938.0 54058.0 66352.0 47247.0 True False 61645.21091211873 56282.37916450435 70431.65120882643 61827.50780127997 54829.496615702745 60825.414015967704 54627.095505414254 56569.7320284314 58878.73904246441 55413.580997329744 1.112456726359 1.0156784339062381 1.2710178613473901 1.1157464774611714 0.9894595445536151 1.0976625751528086 0.9858069903124761 1.020864037484915 1.062532649627925 1.0 15.757951981027967 -6.161783347000661 6.288393850855386 1.0289028818033426 1.1322977578727693 0.36831995913369764 0.06596319746738434 0.2760084810132541 14.6875506933259 0.01962621033966137 0.02547140452501424 6.889959244875344e-07 6.161783347000661 0.10339487606942677 DHLPPPSS(ph)ASPSR ddPTM_PC-9_AZD4547_30min_R2 1 DHLPPPSSASPSR 13 0 Q2YD98;Q2YD98-2 Q2YD98 UVSSA UV-stimulated scaffold protein A 1 DHLPPPS(0.114)S(0.417)AS(0.417)PS(0.053)R 88.311 0.0037775999999999994 2982300.0 18143.0 19190.0 24848.0 32360.0 28083.0 19995.0 18345.0 25263.0 18149.0 23535.0 True False 23912.096602156587 25392.792219096802 24518.499284605223 24899.90195701615 24184.16019786542 18744.709489130873 19977.669461025973 21359.183835987576 19108.31908808216 22711.046813496472 1.0528839466768378 1.1180811006917855 1.0795847274655186 1.0963784347544434 1.0648632974281715 0.8253564726920237 0.8796454705537334 0.9404755320787096 0.8413667254090057 1.0 14.471106584838381 -6.686865116348199 6.7372277837117345 0.8929017340527722 1.0867250702522164 0.7833669786302253 0.048645655987926695 0.09068378785660129 6.614922012053944 0.015321799545258183 0.015249703528760178 2.0565292158844858e-07 6.686865116348199 0.19382333619944425 DHLPPPSSAS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 1 DHLPPPSSASPSR 13 0 Q2YD98;Q2YD98-2 Q2YD98 UVSSA UV-stimulated scaffold protein A 1 DHLPPPS(0.007)S(0.175)AS(0.53)PS(0.288)R 95.073 0.0053387 0.0 18385.0 15328.0 25934.0 30009.0 25397.0 19698.0 20362.0 29027.0 20893.0 20951.0 True False 24231.047568243903 20282.476244623016 25590.09821502542 23090.888684428235 21871.064934130554 18466.280946081515 22174.178553579215 24541.54412410288 21997.361326095124 20217.51186698809 1.198517786345869 1.0032132726352445 1.265739245431575 1.1421231671010863 1.0817881586033564 0.9133804924944275 1.0967807858585232 1.2138755889232458 1.088035039663473 1.0 14.30331783781747 -6.270336900122463 5.516366013470932 1.0699077116012112 1.1502250231564153 0.16914823713447225 0.09410913256808114 0.37427577200204787 41.99435957667268 0.030332321395635874 0.03641022209449733 5.366153602244206e-07 6.270336900122463 0.08031731155520405 DHLPPPSSAS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DHLPPPSSASPSR 13 0 Q2YD98;Q2YD98-2 Q2YD98 UVSSA UV-stimulated scaffold protein A 1 DHLPPPS(0.076)S(0.331)AS(0.493)PS(0.1)R;DHLPPPS(0.012)S(0.26)AS(0.54)PS(0.187)R 79.32600000000001 0.022074 0.0 31572.0 35491.0 36792.0 46794.0 41144.0 42393.0 42916.0 37902.0 42963.0 29161.0 True False 36916.51602457592 39014.31192815231 37669.260814437 44172.28388819488 33082.128554675306 40169.83645138868 38850.685795066616 36907.112660488536 43591.2525969894 34447.658461651 1.0716698223675605 1.132567891997221 1.0935216643642838 1.2823014933618742 0.9603592822282572 1.1661122481258896 1.1278178990980563 1.0713968469460857 1.2654344168419325 1.0 15.072118300343353 -10.758681356661608 3.611061348597915 0.9997828781270858 1.1278712358577239 0.1598781907626391 0.08935595845499483 26384609.703823593 28383021.21484725 59409.4063601949 0.020857852234485497 1.7430853119584544e-11 10.758681356661608 0.1280883577306381 DHLYGTLDPNTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DHLYGTLDPNTR 12 0 Q14204;A0A2R8YFZ7 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ;; 110.15 0.00085168 0.0 72537.0 82515.0 80717.0 74748.0 85393.0 71069.0 85808.0 70446.0 58395.0 63930.0 False True 84816.08142894534 90706.54387736288 82641.59940092705 70560.11189628558 68660.85464877951 67342.0165301758 77679.64504387823 68596.86714370688 59248.91640251371 75520.0029303985 1.123094255003067 1.2010929602447282 1.0943007970628924 0.9343234793213117 0.9091744171681164 0.8917109893684751 1.0285969548421512 0.9083271250257737 0.784546002429572 1.0 16.20457120023002 -5.681192887175178 3.1340584006075214 0.9193235588746032 1.160795927758444 0.7136055687940102 0.06396344607934636 0.1289328702530448 2.52798469159928 0.018356119090972015 0.03390605418591078 2.083565284683688e-06 5.681192887175178 0.24147236888384094 DHLYGTLDPNTR ddPTM_PC-9_Lapatinib_30min_R1 1 DHLYGTLDPNTR 12 0 Q14204;A0A2R8YFZ7 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 95.417 0.003863 6422300.0 32238.0 47881.0 44437.0 42639.0 46665.0 45845.0 46050.0 45214.0 49779.0 33953.0 False True 31778.28020827486 47770.13448629989 40783.561391780495 45774.81429953428 43920.256446919906 43884.31621991471 48434.24367561949 47314.807501822084 44172.364823891374 39821.7308104713 0.7980135358636551 1.199599653607686 1.024153409752252 1.1494933386345323 1.1029218357171677 1.1020193077186675 1.2162767084670134 1.1881655201531434 1.1092527603615876 1.0 15.281268307223069 -4.7536183302888935 24.99018557957877 1.126833681815068 0.7980129401388685 0.6724196387087007 0.0675993113085913 162.21279784411874 518268.04155537544 0.016230655785767333 0.17227121607233384 1.7635251991309912e-05 4.7536183302888935 -0.32882074167619946 DHMNASAQGHSPEEPPPPS(ph)SA ddPTM_PC-9_AZD4547_30min_R2 1 DHMNASAQGHSPEEPPPPSSA 21 0 K7ENY0;Q96FH0 K7ENY0 MEF2BNB Protein MEF2BNB 1 DHMNASAQGHSPEEPPPPS(0.5)S(0.5)A 75.764 0.0059233 0.0 2365.9 2401.1 5545.5 8390.9 5214.7 5264.7 3803.3 7192.4 4106.1 4299.1 True False 3118.20698622291 3177.208618930346 5471.963046634671 6456.507643112702 4490.728917274114 4935.497476740548 4141.786332031622 6080.979844909825 4323.140063230709 4148.589817544198 0.7516305837314053 0.7658526773348561 1.3189935103957464 1.5563138143492576 1.0824711805160938 1.1896807575115171 0.9983600486401899 1.4657944295176248 1.0420745972398489 1.0 12.01840530570661 -5.253417476429666 24.350446091336707 1.2233459031835283 0.7587415157228832 0.48898180541213254 0.18254831676940342 331.4209052990847 1006017.3096553176 0.04627341385023939 0.11771964044256474 5.579336092427909e-06 5.253417476429666 -0.46460438746064514 DHQYQFLEDAVR ddPTM_PC-9_AZD4547_30min_R2 1 DHQYQFLEDAVR 12 0 Q13263-2;Q13263;M0R2I3;M0R3C0 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 0 118.76 0.00047846 3977900.0 19717.0 22863.0 18896.0 19059.0 21991.0 24737.0 21483.0 26072.0 22766.0 17743.0 False True 25986.595860922756 30253.017639667032 18645.42669357293 14665.242008614687 18937.929242291026 23190.191479501376 23394.945381914476 22043.17147495816 23969.364282289847 17121.822970548874 1.5177470241119837 1.7669273705086797 1.0889860691612567 0.8565233990469511 1.1060696793131213 1.3544230377449096 1.3663816885711269 1.2874313391088357 1.3999306220791665 1.0 14.063548694054704 -5.263173312385279 24.999987111305444 1.1910738032313841 1.642337215206996 0.5235008864533834 0.17534196078005718 123.87143305817828 1786020.8243500704 0.05028203554431357 0.1141718366565705 5.455401108550386e-06 5.263173312385279 0.4512634119756118 DHQYQFLEDAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DHQYQFLEDAVR 12 0 Q13263-2;Q13263;M0R2I3;M0R3C0 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 0 88.09200000000001 0.006901399999999999 2164500.0 8358.7 9771.8 10215.0 10161.0 12152.0 8708.8 10224.0 9195.6 9133.6 9561.7 False True 9773.662818149713 10741.879724423614 10458.56434060323 9591.71211240647 9770.90283386191 8252.095197033801 9255.508704650047 8954.225243543573 9267.161620926428 11295.16051962445 0.8652964958903191 0.9510161193159181 0.9259332191368418 0.8491877645954324 0.8650521448443107 0.7305868015506674 0.8194225029887207 0.7927488261885532 0.8204541763550386 1.0 13.463417153088823 -5.9873986316242025 2.203768970083223 0.8208368560219278 0.9177690539983714 0.1711906392239082 0.06863861522413699 0.40469475348659395 3.9526655556001034 0.020584442238630287 0.03235011953803113 1.0294407802179297e-06 5.9873986316242025 0.09693219797644359 DHQYQFLEDAVR ddPTM_PC-9_Lapatinib_30min_R1 2 DHQYQFLEDAVR 12 0 Q13263-2;Q13263;M0R2I3;M0R3C0 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 0 ; 114.87 0.0006286000000000001 6370400.0 26077.4 38459.0 33560.0 34050.7 36227.0 34844.0 33048.6 31675.0 32624.0 33396.9 False True 25705.53149399052 38369.9505484139 30800.826345346293 36554.902067805335 34096.199085022345 33353.803345331195 34759.69479995829 33146.736135272586 28949.541574049923 39169.50966642798 0.6562638060292754 0.9795872063545545 0.786346998153657 0.9332489065885956 0.8704780676446929 0.8515246585769389 0.8874171542093794 0.8462382199203916 0.7390835836493111 1.0 15.257443447939195 -12.062403156617668 2.3131131136319714 3.7048593808791663 0.8472178564529769 0.22354889903937403 0.0888601441740079 3422686.767680307 691997.9247013212 48309446.2524154 0.02104198716481796 8.661574463872831e-13 12.062403156617668 -2.8576415244261897 DHRPPCAQEAPR ddPTM_PC-9_AZD4547_30min_R2 3 DHRPPCAQEAPR 12 1 Q13501;Q13501-2;E7EMC7;E9PFW8;E3W990;C9JRJ8 Q13501 SQSTM1 Sequestosome-1 0 ;; 77.597 0.022543 9149700.0 5410.1 3626.7 7382.200000000001 11524.2 9562.4 8937.0 5886.299999999999 9705.5 7929.400000000001 9444.8 False True 7130.399262929357 4798.95985101607 7284.3072045562085 8867.47373711513 8234.825819038868 8378.167977212426 6410.169296725927 8205.737985202757 8348.531895809067 9114.140426773378 0.7823446786032995 0.5265400384789788 0.7992313990640395 0.9729358252004052 0.903521937718727 0.9192493844620844 0.7033213223153375 0.9003304317210069 0.9159977249510786 1.0 13.153890883821969 -5.496427587764526 7.510957241741754 0.8903626774968316 0.6555298936308168 0.5222355362552326 0.09398157069225554 0.16152057719388 36.4153828715181 0.02443311453763559 0.04883764079748943 3.188397149842128e-06 5.496427587764526 -0.2348327838660148 DHRPPCAQEAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DHRPPCAQEAPR 12 1 Q13501;Q13501-2;E7EMC7;E9PFW8;E3W990;C9JRJ8 Q13501 SQSTM1 Sequestosome-1 0 ; 98.75399999999999 0.0016038 9986500.0 22628.6 22631.3 27651.0 27106.5 24590.6 24849.9 26441.7 21465.8 25199.1 21457.8 False True 26459.175044777585 24877.98589894882 28310.30470700147 25587.81068545872 19772.248455099118 23546.727498251217 23936.950754669895 20902.345494895104 25567.58916548648 25347.929280148666 1.0438397058926308 0.9814602851378521 1.1168685376273635 1.0094635503618008 0.7800340704983675 0.9289408707910485 0.944335550652503 0.8246174771863855 1.008665792101205 1.0 14.629580275129895 -6.019001401200368 24.57995801282738 0.9066896616895874 1.0445248399065579 0.41294127819789417 0.07280589261693407 539.8837677645173 698386.7606624117 0.020371831257145673 0.026764731283303127 9.571909830250702e-07 6.019001401200368 0.13783517821697044 DHRPPCAQEAPR ddPTM_PC-9_Lapatinib_30min_R1 2 DHRPPCAQEAPR 12 1 Q13501;Q13501-2;E7EMC7;E9PFW8;E3W990;C9JRJ8 Q13501 SQSTM1 Sequestosome-1 0 ; 94.402 0.0022168 12051000.0 36798.6 31680.4 37382.5 29553.9 29608.4 31718.4 26685.5 30725.2 29102.0 26454.8 False True 36273.84521596323 31607.045980237977 34309.05515062299 31727.392394920298 27866.89212435409 30361.877971201713 28067.144616845708 32152.80495985721 25824.22630235412 31027.47693119479 1.1690878151775783 1.0186792194005467 1.105763618057159 1.022557923909753 0.8981359388696194 0.9785480797723554 0.9045899761390915 1.0362687572424243 0.8323018452199907 1.0 14.921258765206051 -6.008638453243306 3.9662199810144623 0.9437448543746294 1.0886556899786795 0.5459263523090356 0.06389006142892543 0.16383437784064092 5.8768917561343885 0.01755338493029127 0.025090176458069997 9.803057426631307e-07 6.008638453243306 0.14491083560405005 DHS(ph)PTPSVFNR ddPTM_PC-9_AZD4547_30min_R2 1 DHSPTPSVFNR 11 0 H0Y8P7 H0Y8P7 FIP1L1 1 DHS(0.999)PT(0.001)PSVFNR 61.03 0.034605000000000004 5160100.0 14412.0 12257.0 13792.0 22838.0 22275.0 18182.0 13492.0 18494.0 13850.0 20729.0 True False 18994.7162117776 16218.835551301167 13609.109068467296 17573.05194358267 19182.500744487847 17045.076665735305 14692.761862532698 15636.177249841832 14582.082724664595 20003.284019416536 0.9495798886492861 0.8108086419988874 0.6803437403207082 0.8785083452559631 0.95896757381778 0.852113915354609 0.7345174846425673 0.7816805097935071 0.7289844362810748 1.0 14.287949252028957 -10.012200303812723 7.279371814225884 1.0000006573408948 0.8183368770447609 0.27514522533877617 0.08787219893315278 0.0 0.0 0.09014228777807066 0.021862716108459374 9.722986800816256e-11 10.012200303812723 -0.18166378029613395 DHS(ph)PTPSVFNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DHSPTPSVFNR 11 0 H0Y8P7 H0Y8P7 FIP1L1 1 DHS(0.998)PT(0.002)PSVFNR;DHS(0.996)PT(0.004)PSVFNR 70.628 0.017991999999999998 5927400.0 25059.0 26404.0 28124.0 32610.0 36791.0 35132.0 32944.0 31664.0 29771.0 23789.5 True False 29300.993762189504 29025.214622043157 28794.58282086395 30782.967423046462 29582.06765640334 33289.61607364866 29823.305826094576 30832.85355078118 30206.344553801446 28102.34803242162 1.0426528675961528 1.032839483325622 1.0246326316805876 1.095387737264239 1.05265466153485 1.1845848622770774 1.0612389324795029 1.0971628959690265 1.0748690649960084 1.0 14.778403056373199 -5.761776756159908 24.999977311058224 1.08722232914052 1.0333214353807096 0.18617391543319728 0.04408872325972162 12.657213760413645 938060.5312100241 0.011722182452409463 0.018681659821162894 1.7307057790282055e-06 5.761776756159908 -0.05390089375981044 DHS(ph)PTPSVFNR ddPTM_PC-9_Lapatinib_30min_R1 2 DHSPTPSVFNR 11 0 H0Y8P7 H0Y8P7 FIP1L1 1 DHS(0.989)PT(0.011)PSVFNR;DHS(0.99)PT(0.01)PSVFNR 63.662 0.028263 7309800.0 25035.0 33041.0 35420.0 29896.0 32795.0 31222.0 29490.0 30589.0 35371.0 23858.3 True False 24677.996309143262 32964.49559453298 32507.904325153908 32094.65157013244 30866.062577450753 29886.707842036787 31016.84790432179 32010.276610634646 31387.145506857545 27982.175365813564 0.8819184350939674 1.1780533558804875 1.1617361373865709 1.1469677089274188 1.1030615802358417 1.0680623450937996 1.1084502008452048 1.1439523979876955 1.1216835394864941 1.0 14.772220503148514 -4.752716808205378 24.986312998296356 1.119629131232582 0.881917982165076 0.6700369715134262 0.048886974575854475 193.50005722148484 554250.512977653 0.011956794855990728 0.13883659749336966 1.7671897821684088e-05 4.752716808205378 -0.2377111490675059 DHS(ph)PTPSVFNS(ph)DEERYR ddPTM_PC-9_Lapatinib_30min_R1 2 DHSPTPSVFNSDEERYR 17 1 Q6UN15;Q6UN15-5;Q6UN15-3 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 2 DHS(0.903)PT(0.097)PSVFNS(1)DEERYR;DHS(0.972)PT(0.028)PSVFNS(1)DEERYR 76.533 0.0036491999999999996 11977000.0 23609.9 24998.2 25096.0 25613.3 24508.8 28156.2 24167.2 23373.0 27252.9 18927.6 True False 23273.218496474597 24940.31820378484 23032.703753361446 27496.987525464043 23067.240570154732 26952.024961307958 25418.45936498223 24458.99490733153 24183.391416240353 22199.210440558316 1.0483804619444506 1.123477714244218 1.0375460791740738 1.2386470950888686 1.0391018469742739 1.2140983587446053 1.1450163704265037 1.101795713537836 1.0893807003179223 1.0 14.438220744694748 -8.72085487185087 1.7115337514932625 1.0003419917150314 1.1218848819798348 0.23135321439488954 0.06506018659010122 1.0442153816150685 5.684168785415833 0.05939216167306167 0.016875007126853272 1.901713669244338e-09 8.72085487185087 0.12154289026480347 DHS(ph)PTPSVFNSDEER ddPTM_PC-9_AZD4547_30min_R2 3 DHSPTPSVFNSDEER 15 0 Q6UN15;Q6UN15-5;Q6UN15-3 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 DHS(0.857)PT(0.143)PSVFNSDEER;DHS(0.491)PT(0.491)PS(0.015)VFNS(0.002)DEER;DHS(0.94)PT(0.06)PSVFNSDEER 128.95 9.361100000000001e-06 154309000.0 167523.0 172357.0 181844.0 263481.0 209961.0 239807.0 191762.0 278620.0 173865.0 216244.0 True False 220791.8293051357 228068.02962516257 179432.62974524114 202739.52619087094 180811.53934066996 224811.83038059488 208828.44650778195 235565.68105066076 183055.14894756756 208673.36337955086 1.0580738515415735 1.092942702084766 0.8598731857255568 0.9715639931585949 0.8664811666058033 1.0773384141592148 1.0007431860287266 1.1288727858485519 0.8772329442671274 1.0 17.670886930359693 DHS(ph)PTPSVFNSDEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DHSPTPSVFNSDEER 15 0 Q6UN15;Q6UN15-5;Q6UN15-3 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 DHS(0.999)PT(0.001)PSVFNSDEER;DHS(0.999)PTPSVFNSDEER;DHS(0.999)PT(0.001)PSVFNSDEER 217.79 7.3028e-18 96156000.0 132780.0 155853.0 103620.0 145753.3 177942.0 134108.0 144996.3 133921.0 106706.7 99130.2 True False 155257.03147545853 171325.05584340566 106090.6937810383 137587.21513957417 143075.54246733506 127075.14039635855 131261.20078169464 130405.71565102885 108267.08361825671 117101.72054576859 1.325830489525362 1.4630447361910806 0.9059704100553613 1.174937605513652 1.221805638725989 1.085168858357567 1.1209160733927208 1.1136105861062944 0.9245558742746319 1.0 16.837402747582622 -1.5228787452804395 0.37921212184098024 1.0436612861778642 6.056032808901358 0.41162842935381105 0.1263300847355822 69.17782699000529 0.9453115587296257 0.09746444380707735 254.62769631758522 0.029999999999992956 1.5228787452804395 5.012371522723495 DHS(ph)PTPSVFNSDEER ddPTM_PC-9_Lapatinib_30min_R1 4 DHSPTPSVFNSDEER 15 0 Q6UN15;Q6UN15-5;Q6UN15-3 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 DHS(0.675)PT(0.009)PS(0.316)VFNS(0.001)DEER;DHS(0.995)PT(0.005)PSVFNSDEER;DHS(0.984)PT(0.009)PS(0.007)VFNSDEER;DHS(0.998)PT(0.002)PSVFNSDEER 202.63 3.8436e-50 173099000.0 129020.7 228195.0 247488.9 197572.0 259575.0 232827.0 222455.0 207629.0 201308.0 169987.4 True False 127180.84115850131 227666.62849775885 227141.31797678125 212102.1039608715 244307.30884408506 222869.53195624577 233972.63141932563 217276.20132692967 178634.57317278188 199369.49559602694 0.6379152476575548 1.141933111768859 1.1392982527127773 1.0638643756748225 1.2253996435799461 1.1178717751678313 1.1735628397907643 1.0898166777087417 0.895997517768419 1.0 17.60508516241306 -4.758668535939654 24.99781831531861 1.1047827122217961 0.6379146223007905 0.703643233948432 0.0885951167932429 40.90559402969668 368969.53352361394 0.021904366946406194 0.14754889979705765 1.7431367699965402e-05 4.758668535939654 -0.4668680899210056 DHS(ph)PTPSVFNSDEERYR ddPTM_PC-9_AZD4547_30min_R2 1 DHSPTPSVFNSDEERYR 17 1 Q6UN15;Q6UN15-5;Q6UN15-3 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 DHS(0.948)PT(0.05)PS(0.001)VFNSDEERYR 50.873999999999995 0.032962 13846000.0 11159.0 2636.5 12244.0 20544.0 14798.0 11867.0 8835.8 11482.0 5796.1 9058.8 True False 14707.329878380935 3488.69706543245 12081.636559912524 15807.898201635966 12743.55313207324 11124.954614029306 9622.169082787314 9707.720730111598 6102.470013027329 8741.654169284127 1.6824424294956237 0.3990888907148505 1.3820767014970938 1.8083417503726882 1.457796532016873 1.2726372375973725 1.1007263495503041 1.1105130152851361 0.6980909899718754 1.0 13.093690589103701 -7.716227642755359 1.640277649572913 0.8737380008551237 1.3182236608365139 0.20489541822219204 0.3631006155081056 0.7044039556598466 3.623869063001927 0.2849440473186323 0.116592619559684 1.9220839721830187e-08 7.716227642755359 0.4444856599813902 DHS(ph)PTPSVFNSDEERYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DHSPTPSVFNSDEERYR 17 1 Q6UN15;Q6UN15-5;Q6UN15-3 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 DHS(0.632)PT(0.317)PS(0.052)VFNSDEERYR 65.374 0.00909 10528000.0 11652.0 3915.1 9443.1 9841.6 12340.0 15482.0 12229.0 12250.0 15419.0 8020.1 True False 13624.453462509759 4303.765254005494 9668.259317156184 9290.207058897702 9922.065583431202 14670.096665496652 11070.580589707097 11928.450479947871 15644.473705117878 9474.080642923329 1.4380765771385484 0.45426732325950747 1.0204957801766124 0.980591933829171 1.047285320591238 1.5484454078881513 1.1685123873181589 1.259061531089862 1.651292013943699 1.0 13.209770236785152 -6.590524748671403 6.555496610087075 1.3311317910737972 0.9483205691348251 0.2677750400205058 0.27956429864116433 0.2597661145631723 19.7775664789695 0.08837807999658041 0.08846110271391296 2.567291904441725e-07 6.590524748671403 -0.3828112219389721 DHS(ph)PTPSVFNSDEERYR ddPTM_PC-9_Lapatinib_30min_R1 2 DHSPTPSVFNSDEERYR 17 1 Q6UN15;Q6UN15-5;Q6UN15-3 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 DHS(0.969)PT(0.031)PSVFNSDEERYR;DHS(0.979)PT(0.021)PSVFNSDEERYR 89.911 0.0010431 17065400.0 15963.7 9931.9 18996.0 9668.6 9631.1 11752.0 7459.1 4964.4 16936.1 6560.4 True False 15736.054710615957 9908.903295764123 17434.222206680508 10379.661097504097 9064.617633471136 11249.394355250039 7845.295700343398 5195.064147433215 15028.57807296061 7694.356398816482 2.0451424258221804 1.2878144424513887 2.2658454200746636 1.3489966619041274 1.1780865303906929 1.4620318805326433 1.0196168845974085 0.675178517625243 1.9531949514675784 1.0 12.90958494077137 -5.956610849169114 11.724974740709941 1.2067122070781622 1.8087639500513633 0.35733856710250544 0.38983302958581517 0.8460958824371365 225.85564498547294 0.10507181761958237 0.15584042259329242 1.1050683761243534e-06 5.956610849169114 0.6020517429732011 DHSPT(ph)PSVFNSDEERYR ddPTM_PC-9_AZD4547_30min_R2 1 DHSPTPSVFNSDEERYR 17 1 Q6UN15;Q6UN15-5;Q6UN15-3 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 DHS(0.053)PT(0.795)PS(0.152)VFNSDEERYR 105.95 0.00049653 14366000.0 6664.3 7752.4 13510.0 24134.0 16878.0 13483.0 7436.5 13981.0 8341.1 15630.0 True False 8783.408773948751 10258.211693555293 13330.848572722816 18570.279166583063 14534.781035486689 12639.905878567217 8098.33409359061 11820.557701418767 8781.993517306855 15082.798457401745 0.5823460943773584 0.6801265509532265 0.8838445073951661 1.231222390130783 0.9636660647914366 0.8380345274960761 0.536925167863423 0.7837111750053212 0.5822522618802993 1.0 13.880616510148792 -7.021636605921722 22.700302974308006 0.7048096957323924 0.8810255727905048 0.09918352859616497 0.19890031534804198 508.19396060835123 533175.5392690045 0.08029568693305111 0.06294538818793974 9.51400541085702e-08 7.021636605921722 0.17621587705811237 DHSPT(ph)PSVFNSDEERYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DHSPTPSVFNSDEERYR 17 1 Q6UN15;Q6UN15-5;Q6UN15-3 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 DHS(0.02)PT(0.846)PS(0.128)VFNS(0.006)DEERYR 69.024 0.011991 9948500.0 11319.0 2677.9 6168.3 10891.0 14439.0 9128.8 8014.2 18199.0 11954.0 8590.4 True False 13235.083139559561 2943.744214375446 6315.375665408015 10280.812579098403 11609.781601228777 8650.069657666052 7255.036958216582 17721.295533434408 12128.804635253846 10147.771518431016 1.3042354289827256 0.29008775069766146 0.6223411370602536 1.0131103721073882 1.1440720339576396 0.8524107624965004 0.7149389346261424 1.7463238604897522 1.1952185377079838 1.0 13.308875321511973 -7.741125388679688 24.9989345095785 1.3530786138126698 0.8363696000694419 0.30791320501553954 0.3175339353710064 254.10219899249105 312705.5534419768 0.14995891090449975 0.08644643592651817 1.8149915661936902e-08 7.741125388679688 -0.5167090137432279 DHSPTPSVFNS(ph)DEER ddPTM_PC-9_Lapatinib_30min_R1 1 DHSPTPSVFNSDEER 15 0 Q6UN15;Q6UN15-5;Q6UN15-3 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 DHS(0.155)PT(0.048)PS(0.155)VFNS(0.642)DEER 116.78 0.00013893 28373000.0 18505.0 32618.0 45888.0 45875.0 56908.0 45807.0 48995.0 54514.0 54366.0 49142.0 True False 18241.115306598625 32542.475025043947 42115.265772802435 49248.800534513844 53560.78332543274 43847.941391332395 51531.72136562385 57046.91945314124 48242.728580639974 57636.129222401 0.31648751490946736 0.5646193709413072 0.7307094758270791 0.8544779324870533 0.9292918183099581 0.7607717933682879 0.894087130084291 0.9897770759901976 0.8370223544069963 1.0 15.814685828539528 -4.79231792044574 0.9027493175522256 0.9034435062054623 3.679705510316631e-18 0.8934646489997148 0.06527494552241553 0.6549145263402499 0.420573171129844 0.023089073975407857 0.5857824662026555 1.6131772160444974e-05 4.79231792044574 -0.9034435062054623 down DHTVS(ph)GDEDYCPR ddPTM_PC-9_AZD4547_30min_R2 2 DHTVSGDEDYCPR 13 0 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 DHT(0.172)VS(0.828)GDEDYCPR;DHT(0.209)VS(0.791)GDEDYCPR 164.64 0.00032517 20543700.0 27614.6 30017.4 41408.0 51176.0 47613.8 34182.9 33205.3 51175.5 30022.7 47134.0 True False 36395.46838063789 39719.93752774968 40858.902864493444 39378.16386131828 41003.44574401329 32045.43785926539 36160.507372810345 43267.50237100035 31609.63862944316 45483.85300647304 0.8001843725829091 0.8732755670918411 0.8983166588520679 0.8657613913164783 0.901494553202823 0.7045453659061127 0.7950185611510124 0.9512717043747972 0.6949639606157516 1.0 15.473066851850872 -3.252955543176629 15.348256499550136 0.8456707580671071 0.3475766720900534 0.0 0.09449137114181928 0.0 0.0 0.02051101158057181 0.0 0.0005585273658100091 3.252955543176629 -0.49809408597705374 DHTVS(ph)GDEDYCPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DHTVSGDEDYCPR 13 0 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 DHT(0.297)VS(0.703)GDEDYCPR;DHT(0.003)VS(0.997)GDEDYCPR 179.67 0.00010719 12618700.0 37878.2 37097.2 48914.9 41151.7 62713.5 53124.6 45066.3 51628.7 45568.5 31806.9 True False 44290.23113144844 40779.96484914627 50081.21672679128 38846.103664611495 50425.23986762664 50338.65245548662 40797.2938122428 50273.50133012941 46234.85310536766 37573.239186718136 1.178770638095656 1.0853459997551047 1.3328959070554296 1.0338768896545738 1.342051975264661 1.3397474783936372 1.0858072046837086 1.3380135015854775 1.2305261432373749 1.0 15.197417875544375 -7.299671445617152 24.996556096758532 1.1917545965162466 1.2151019367659346 0.023656977465105977 0.12938968869217854 5422.884627739506 3545522.3878870183 0.05356894581319944 0.03611724517205971 5.0156653746881984e-08 7.299671445617152 0.023347340249687987 DHTVS(ph)GDEDYCPR ddPTM_PC-9_Lapatinib_30min_R1 2 DHTVSGDEDYCPR 13 0 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 DHT(0.017)VS(0.983)GDEDYCPR;DHT(0.023)VS(0.977)GDEDYCPR 180.84 9.1106e-05 24515300.0 11344.7 13850.0 15004.1 11735.5 10251.1 13643.2 10616.0 11981.5 11510.5 9457.1 True False 11182.922497636813 13817.931175941458 13770.520815500902 12598.567818480376 9648.150452438033 13059.71213985255 11165.64453551306 12538.204230616213 10214.066279061477 11091.747134206349 1.0082201083677147 1.2457849073504124 1.2415105256982788 1.1358506163223894 0.8698494777872873 1.1774260611817504 1.006662377027945 1.1304084089646318 0.9208708200317557 1.0 13.437199011354583 -6.01723641836987 24.806689449293767 1.028902192062851 1.1758077396094182 0.30229313191198937 0.10390409778158942 801.1899692694856 1153075.5953664265 0.029217837487673128 0.03865277419337407 9.610889446819718e-07 6.01723641836987 0.14690554754656726 DHVDLLAS(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 1 DHVDLLASSR 10 0 E9PEK0;Q12766-2;Q12766 E9PEK0 HMGXB3 HMG domain-containing protein 3 1 DHVDLLAS(0.5)S(0.5)R 61.691 0.035565 5677900.0 6684.8 6501.3 4403.6 4205.1 7198.6 6530.2 6035.0 5562.8 6835.7 4895.0 True False 6589.473526157819 6486.246639288681 4041.553006387573 4514.357081802378 6775.192500992135 6250.918568639698 6347.462770518213 5821.267995999819 6065.791482887847 5741.094227822488 1.147773101201495 1.1297927506319327 0.7039691121600827 0.7863234607655284 1.180122156532147 1.0888026429433084 1.105618984575648 1.013964893275709 1.056556684523973 1.0 12.48711001922905 -6.274309572278166 24.960151601017472 1.0771791240532491 0.9383812146703412 0.18822930381606096 0.1343402759401919 1399.5790259209784 2714306.1188010615 0.04568504104559727 0.052116337109671305 5.317290988648859e-07 6.274309572278166 -0.13879790938290792 DHVFEDSYR ddPTM_PC-9_AZD4547_30min_R2 1 DHVFEDSYR 9 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 0 96.665 0.0042232 5522200.0 25976.0 26751.0 40506.0 53248.0 48493.0 41072.0 35224.0 49600.0 35306.0 43201.0 False True 34235.827665635225 35397.737605683105 39968.86397384979 40972.49627339917 41760.584000109986 38503.76134721593 38358.86776207028 41935.45969461202 37172.20308137247 41688.546139360995 0.8212286307895695 0.8490998339772202 0.9587492890790082 0.9828238225538465 1.0017280012718164 0.9236052804168651 0.9201296594474678 1.0059228152122557 0.8916646542939923 1.0 15.347363439531978 -5.215201887266261 3.8768200097540566 0.960777239574095 0.8280939020676155 0.6507478184851383 0.036957504093809025 0.13163585956076773 4.18492582440493 0.009497393417851909 0.02737006861112197 6.092536121767929e-06 5.215201887266261 -0.13268333750647954 DHVFEDSYR ddPTM_PC-9_Lapatinib_30min_R1 1 DHVFEDSYR 9 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 0 105.98 0.0021824 4051500.0 55387.0 47113.0 49238.0 36395.0 45733.0 41251.0 37891.0 36561.0 44748.0 32858.0 False True 54597.171223268175 47003.91274311412 45189.84170417645 39071.60971016089 43043.07485453741 39486.79089077765 39852.810577913086 38259.75753249255 39708.009022669976 38537.4615194671 1.4167298278245066 1.2196940558570577 1.172621130775542 1.0138604923529788 1.1169151562511275 1.024633936276031 1.0341316995615173 0.9927939211347829 1.0303742762769046 1.0 15.233973923318768 -1.5228787452803376 0.50701508952935 1.0119559652302885 14.67139948595746 0.9249771420394347 0.035069924558094455 25.45204083085687 0.26521524635573396 0.01805168897836289 371.5735450186776 0.029999999999999995 1.5228787452803376 13.659443520727171 DHYEATAMHR ddPTM_PC-9_AZD4547_30min_R2 9 DHYEATAMHR 10 0 B1AJY6;B1AJY5;B1AJY7;O75832-2;O75832 B1AJY6 PSMD10 26S proteasome non-ATPase regulatory subunit 10 0 ;;;;;;;; 154.85 0.00010437 48508300.0 78987.1 79169.0 100396.30000000002 126285.4 123004.80000000002 116666.59999999999 104582.8 124911.70000000001 97892.90000000001 101010.6 False True 104103.35476625693 104758.83101582467 99064.97946422304 97172.25211998043 105927.70673739957 109371.4190589965 113890.46659627071 105609.46695031195 103067.31884168384 97474.24963923392 1.0680087833613316 1.074733392701683 1.0163194877711461 0.9969017712845062 1.0867250287071004 1.1220544858133885 1.1684159356732218 1.0834601686208165 1.0573799667414796 1.0 16.572733523289592 -6.454190272999947 9.381927345428172 1.0974735818924868 1.0400470281808556 0.181898428880931 0.04620804591755199 0.6888124684391238 90.57021011287121 0.014762534743130851 0.01671796577487353 3.514064486837001e-07 6.454190272999947 -0.05742655371163119 DHYEATAMHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DHYEATAMHR 10 0 B1AJY6;B1AJY5;B1AJY7;O75832-2;O75832 B1AJY6 PSMD10 26S proteasome non-ATPase regulatory subunit 10 0 ;;; 86.189 0.007752199999999999 17085500.0 24770.9 25793.62 29467.3 30205.960000000003 36523.3 30096.61 30165.100000000002 28479.74 24758.4 25969.75 False True 28964.12412242389 28354.24012950401 30169.91218735758 28513.617990243605 29366.821549702818 28518.290789546125 27307.643351588333 27732.177001778844 25120.44476170897 30677.86009857212 0.9441376950464679 0.9242574298988911 0.9834425246877574 0.9294526377858654 0.9572643416243258 0.9296049560794981 0.8901417264387143 0.9039801639577076 0.8188460564391903 1.0 14.904910232245298 -7.103135858599498 3.472454272721776 0.8952614222146409 0.9472749819173361 0.17615242177207147 0.04382980698450615 0.3644802355076772 8.158033609055519 0.016692162782701678 0.01279069492876227 7.886133802694157e-08 7.103135858599498 0.05201355970269517 DHYEATAMHR ddPTM_PC-9_Lapatinib_30min_R1 7 DHYEATAMHR 10 0 B1AJY6;B1AJY5;B1AJY7;O75832-2;O75832 B1AJY6 PSMD10 26S proteasome non-ATPase regulatory subunit 10 0 ;;;;;; 122.94 0.00020899999999999998 40252800.0 80716.5 78155.09999999999 94782.20000000001 79648.1 94693.8 88517.4 76160.40000000001 80387.8 92781.3 72592.09999999999 False True 79565.4679084067 77974.13666778516 86989.57338587256 85505.68697227282 89124.09685917382 84731.71714613761 80103.61285630077 84122.91065809205 82331.29296359728 85139.54776210681 0.9345300744458385 0.9158392159382508 1.0217293334577604 1.0043004598895575 1.04680021449257 0.9952098569150409 0.9408508144783992 0.9880591672056398 0.9670158595820096 1.0 16.377541806489617 -5.252764480223245 24.983591402789195 0.9952542012970537 0.9251846369510552 0.515092784407245 0.02728710283905499 541.7772532841005 1560302.9139548228 0.00765788834229769 0.019551825294375866 5.587731376761801e-06 5.252764480223245 -0.07006956434599843 DHYPCVSS(ph)LEQLTELGR ddPTM_PC-9_AZD4547_30min_R2 1 DHYPCVSSLEQLTELGR 17 0 Q8WWK9-6;Q8WWK9-5;Q8WWK9 Q8WWK9-6 CKAP2 Cytoskeleton-associated protein 2 1 DHYPCVS(0.079)S(0.92)LEQLT(0.001)ELGR 68.189 0.044695 0.0 4196.2 5221.3 7084.0 7037.6 6334.6 5753.4 6480.7 5762.4 5079.2 6504.9 True False 5530.5043136178965 6908.983116913505 6990.0615313966255 5415.190049836122 5455.150133155228 5393.638988485399 7057.469745220555 4871.953486778879 5347.676142607687 6277.165430937461 0.8810512283713934 1.1006533431255587 1.1135697486871392 0.8626807926945765 0.869046736647903 0.8592475453813057 1.124308387737769 0.7761390934142194 0.8519253158840264 1.0 12.615897515448319 -5.770614588693118 24.999240597730466 0.902449383333595 1.0386476371577107 0.22064198113428957 0.10775104605720362 267.9017959447402 729939.8210148938 0.030451495716077626 0.04589265605537728 1.6958420949211601e-06 5.770614588693118 0.13619825382411566 DHYQDPVPGIT(ph)PSSSSR ddPTM_PC-9_AZD4547_30min_R2 3 DHYQDPVPGITPSSSSR 17 0 Q7KZ85;Q7KZ85-2 Q7KZ85 SUPT6H Transcription elongation factor SPT6 1 DHYQDPVPGIT(0.769)PS(0.046)S(0.018)S(0.046)S(0.12)R;DHYQDPVPGIT(0.996)PS(0.003)SSS(0.001)R;DHYQDPVPGIT(0.976)PS(0.017)S(0.006)S(0.001)S(0.001)R 156.17 2.5393000000000003e-17 7699500.0 44179.0 40339.6 62630.0 89421.0 68050.0 72082.0 69306.0 79603.0 56504.0 77780.0 True False 58227.003019714306 53378.586816127034 61799.48527828497 68806.36999067815 58602.43212850281 67574.70114506278 75474.0997364875 67302.18544496367 59490.686084797744 75056.94587438961 0.7757710141465016 0.7111745114896887 0.8233679715893122 0.9167222192310888 0.7807729377448425 0.9003124275553573 1.0055578315536047 0.8966816416643998 0.7926073382249986 1.0 16.19569796658334 -5.53419290898945 0.7281915319085024 0.912866545632909 0.7067839152605875 0.42247117110901966 0.07144303516470212 1.3035391362387325 1.016638412580671 0.03539036894007995 0.18856375251816332 2.9228537888911533e-06 5.53419290898945 -0.20608263037232155 DHYQDPVPGIT(ph)PSSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DHYQDPVPGITPSSSSR 17 0 Q7KZ85;Q7KZ85-2 Q7KZ85 SUPT6H Transcription elongation factor SPT6 1 DHYQDPVPGIT(0.646)PS(0.04)S(0.06)S(0.06)S(0.195)R;DHYQDPVPGIT(0.462)PS(0.106)S(0.039)S(0.106)S(0.287)R 94.671 0.0036185 17351200.0 57620.0 56731.0 61481.0 77373.0 95519.0 75143.0 77524.0 75107.0 75119.0 59628.0 True False 67373.92795312506 62362.87875788247 62946.94020799092 73038.04165665066 76802.73763887875 71202.36879830869 70180.36549484445 73135.52083244435 76217.4732638141 70438.0843850118 0.9564985837045458 0.8853573929837363 0.8936492347509825 1.0369112433187082 1.0903581252874228 1.0108504429098233 0.9963411996164082 1.0382951420525361 1.0820492057565392 1.0 16.104068054110066 -5.765831964055561 24.99982982368678 1.037510890456352 0.9091872899390959 0.7366579095664698 0.03411438554553503 53.33966665804478 303578.3821512905 0.009798317796960936 0.015118222487193899 1.7146205951424774e-06 5.765831964055561 -0.128323600517256 DHYQDPVPGIT(ph)PSSSSR ddPTM_PC-9_Lapatinib_30min_R1 4 DHYQDPVPGITPSSSSR 17 0 Q7KZ85;Q7KZ85-2 Q7KZ85 SUPT6H Transcription elongation factor SPT6 1 DHYQDPVPGIT(0.586)PS(0.137)S(0.051)S(0.137)S(0.088)R;DHYQDPVPGIT(0.724)PS(0.147)S(0.049)S(0.049)S(0.031)R;DHYQDPVPGIT(0.945)PS(0.049)S(0.004)S(0.001)SR;DHYQDPVPGIT(0.5)PS(0.111)S(0.039)S(0.026)S(0.324)R 199.91 3.9967e-12 29527400.0 75338.0 92731.0 107395.0 93377.0 118645.0 111666.0 89859.0 95637.0 113107.0 93028.0 True False 74263.66630470289 92516.28706687567 98565.39765668848 100244.25607654043 111666.53436504469 106890.30548615986 94511.45933653618 100080.64416003335 100367.69859048743 109107.76584798192 0.6806451009928408 0.8479349416408829 0.9033765551942292 0.9187637130816988 1.0234517543015944 0.9796764204216993 0.8662211951825451 0.9172641688903619 0.9198950946381591 1.0 16.735394264930996 -4.506766017971961 1.2059734953548134 0.9435353658853373 0.4070556700942969 0.7747212827274723 0.04357525969402853 1.3211352793146018 1.0675889434347252 0.014135486005368644 1.0397701648420863 3.11339326807757e-05 4.506766017971961 -0.5364796957910404 DHYQDPVPGITPSSSS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DHYQDPVPGITPSSSSR 17 0 Q7KZ85;Q7KZ85-2 Q7KZ85 SUPT6H Transcription elongation factor SPT6 1 DHYQDPVPGIT(0.077)PS(0.019)S(0.022)S(0.063)S(0.817)R;DHYQDPVPGIT(0.02)PS(0.013)S(0.005)S(0.219)S(0.743)R 101.89 0.00057615 8986800.0 53124.0 51031.0 68320.0 66510.0 84240.0 72949.0 79689.0 73144.0 69659.0 62739.0 True False 62116.84395317271 56097.02042787012 69949.0079050429 62783.66032832937 67733.77672189998 69123.42602062489 72140.28102160168 71224.047502474 70677.63109311945 74113.08405834921 0.838136001792452 0.7569111600281666 0.9438145611370331 0.8471332845749586 0.9139246812151711 0.9326750721398132 0.9733811774018966 0.9610185354909712 0.9536457967054099 1.0 16.177440640565962 -5.208278437288348 0.3425510069230214 0.9937237911308185 0.6912231796511538 0.6837537667806036 0.040084809374701394 2.749969569245415 0.32394046957347644 0.03928147874743203 0.33707165060328703 6.190440628580879e-06 5.208278437288348 -0.3025006114796648 DIAAHIK ddPTM_PC-9_Lapatinib_30min_R1 1 DIAAHIK 7 0 P63167;F8VXL2;F8VRV5 P63167 DYNLL1 Dynein light chain 1, cytoplasmic 0 82.671 0.018581 11551000.0 69229.0 88922.0 95886.0 84150.0 94308.0 83403.0 90992.0 88678.0 86188.0 78220.0 False True 68241.78176495625 88716.10657235139 88002.62321066359 90338.67171617082 88760.98885666182 79836.04811188886 95703.12053272466 92798.30361495499 76480.5998401243 91740.2227784016 0.7438589061397223 0.9670360926269499 0.9592588784445599 0.9847226110883094 0.967525324971838 0.8702403994018276 1.0431969493239126 1.0115334452490832 0.8336648584870248 1.0 16.485266790358303 -4.760452180664225 24.98468509892334 0.9608754279155454 0.7438586486957254 0.5384540527175122 0.05993706381009059 18.517137724039245 468406.9615082328 0.014467099566106516 0.08556040575826163 1.7359923991552583e-05 4.760452180664225 -0.21701677921982 DIAWTEDSKR ddPTM_PC-9_AZD4547_30min_R2 2 DIAWTEDSKR 10 1 O75083;D6RD66 O75083 WDR1 WD repeat-containing protein 1 0 ; 95.775 0.0036618 12300100.0 16287.3 17431.6 27904.0 25712.0 27450.0 25240.8 19213.6 28825.0 23077.0 24977.0 False True 21466.32260311443 23066.023806482957 27533.974727850302 19784.495646440042 23639.0413214901 23662.488785859194 20923.573178324797 24370.758582604663 24296.803107370753 24102.562832407133 0.8906240698292821 0.956994655168765 1.1423670967814867 0.8208461392262724 0.9807687873633999 0.9817416077448727 0.8681057414438924 1.0111272710733037 1.0080589054497746 1.0 14.55689893633769 DIAWTEDSKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DIAWTEDSKR 10 1 O75083;D6RD66 O75083 WDR1 WD repeat-containing protein 1 0 ; 94.40899999999999 0.0039951 7358400.0 34712.0 30626.0 29545.0 26602.0 44681.0 37973.0 39097.0 34535.0 32666.0 29048.0 False True 40588.05600674897 33666.3468798172 30249.464850036456 25111.57618484765 35926.07879524223 35981.629032353965 35393.44912223228 33628.49284285714 33143.678451999505 34314.17245615852 1.1828365104420417 0.981120757693661 0.8815443498946293 0.7318135448824079 1.046974944278291 1.0485938158154875 1.0314527959971262 0.9800175972718723 0.9658889047767508 1.0 15.066516941639005 DIAWTEDSKR ddPTM_PC-9_Lapatinib_30min_R1 2 DIAWTEDSKR 10 1 O75083;D6RD66 O75083 WDR1 WD repeat-containing protein 1 0 ; 94.40899999999999 0.0039951 12933600.0 28725.0 29081.0 24570.6 24698.8 26293.0 24632.0 23102.5 20402.3 25482.1 20208.7 False True 28315.37623248016 29013.66473123131 22550.500113258797 26515.232144781483 24746.497434026915 23578.5467799965 24298.634408599337 21350.265340257993 22612.03755959102 23701.74686859986 1.1946535582148357 1.2241150364182098 0.9514277676779074 1.1187037095526884 1.0440790533802866 0.9948020671519965 1.0251832720730907 0.9007886827338825 0.9540240930320418 1.0 14.532705772250699 -2.8403610737749543 0.35080641577970284 0.9543858599454854 2.254331633872273 0.6088889553496488 0.06331578472371238 16.059521381652374 0.5286453638750442 0.054412812982117864 11.667537074470099 0.0014442385270797347 2.8403610737749543 1.2999457739267877 DICNDVLSLLEK ddPTM_PC-9_Lapatinib_30min_R1 1 DICNDVLSLLEK 12 0 P63104;E7EX29;E7ESK7;B0AZS6 P63104 YWHAZ 14-3-3 protein zeta/delta 0 151.78 0.00088487 26402000.0 24519.0 31577.0 39308.0 27131.0 28442.0 26521.0 36839.0 26459.0 25191.0 28510.0 False True 24169.354563766086 31503.885396585094 36076.24797326794 29126.30424636282 26769.09747912345 25386.758653470566 38746.34316538864 27688.38173332839 22353.72430700993 33437.91551281293 0.7228128366585751 0.9421605657360208 1.0789024202015238 0.8710562186569925 0.8005611913477656 0.7592207308419906 1.158754742069421 0.8280534629235068 0.6685142887703124 1.0 15.029197293563309 -5.9564879968316164 24.999985541039884 0.8664974534468106 0.9269788018124432 0.016570813110225457 0.14992112114560588 621.1944371998054 356905.5112463271 0.04339895432143515 0.06437099482300654 1.105381019831237e-06 5.9564879968316164 0.06048134836563257 DIDAFWLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DIDAFWLQR 9 0 O75643;A0A494C1A5;O75643-2 O75643 SNRNP200 U5 small nuclear ribonucleoprotein 200 kDa helicase 0 ; 112.41 0.0099977 4912400.0 42396.0 40834.0 51443.0 53421.0 55638.0 65554.0 48168.0 55990.0 48617.0 45572.0 False True 49572.8054408311 44887.72965749545 52669.5962186639 50427.994563218796 44736.133300724854 62116.23283877841 43605.17833387941 54520.321826308726 49327.931650672304 53833.84285224649 0.9208483514151066 0.8338199036003294 0.9783733322405015 0.9367340671113623 0.8310038988579841 1.1538509894094675 0.8099956462992827 1.0127518107140587 0.9162996553312903 1.0 15.716225793314681 -5.480273260885162 0.8663999877692135 0.9586982891981368 0.874088877018456 0.06534182622070606 0.09525981174716444 3.0119780222241372 3.4013657308298817 0.03717787770846798 0.20022285513323076 3.3092283718203062e-06 5.480273260885162 -0.08460941217968088 DIDDDLEGEVTEECGK ddPTM_PC-9_AZD4547_30min_R2 2 DIDDDLEGEVTEECGK 16 0 A0A0J9YYL3;A0A0J9YXJ8;A0A0J9YVP6;A0A0J9YXX5;Q9UHX1-4;Q9UHX1-6;Q9UHX1-3;Q9UHX1-5;Q9UHX1-2;Q9UHX1 A0A0J9YYL3 PUF60 Poly(U)-binding-splicing factor PUF60 0 ; 210.64 2.8052999999999995e-63 0.0 9127.6 6610.9 11199.6 14444.400000000001 13534.9 8431.1 10893.099999999999 15757.3 10826.0 9535.4 False True 12029.9869341258 8747.744141804433 11051.08598631136 11114.466743755382 11655.812764380193 7903.9019841866075 11862.564797269124 13322.371351732052 11398.240258282956 9201.568548349878 1.3073843737525754 0.9506796689976482 1.2010002347146733 1.2078882731084521 1.2667202013585428 0.8589733307593539 1.2891894175364746 1.4478369945003735 1.2387279623458338 1.0 13.167664096270723 DIDDDLEGEVTEECGK ddPTM_PC-9_Lapatinib_30min_R1 1 DIDDDLEGEVTEECGK 16 0 A0A0J9YYL3;A0A0J9YXJ8;A0A0J9YVP6;A0A0J9YXX5;Q9UHX1-4;Q9UHX1-6;Q9UHX1-3;Q9UHX1-5;Q9UHX1-2;Q9UHX1 A0A0J9YYL3 PUF60 Poly(U)-binding-splicing factor PUF60 0 180.61 4.725399999999999e-29 0.0 3331.7 4628.1 4936.5 4984.3 4063.5 3993.0 5164.1 5254.7 4660.3 3455.5 False True 3284.1893470410473 4617.383918799617 4530.640025441061 5350.862049137379 3824.4929191483775 3822.228698137624 5431.471829864638 5498.852545225472 4135.407938865402 4052.7785708356737 0.8103549921711748 1.1393131497553106 1.117909588755759 1.3202946955066541 0.9436718173230411 0.9431131337011313 1.340184699196305 1.3568105064500529 1.0203883253391488 1.0 11.984695638560522 -7.258354636080394 24.94944270874451 1.2090800882275239 1.0611437033041653 0.11711384379344358 0.1689525626556528 540.0563228429934 4368000.330225403 0.0675721042738038 0.05006851537933494 5.516268080354352e-08 7.258354636080394 -0.1479363849233586 DIDECR ddPTM_PC-9_AZD4547_30min_R2 1 DIDECR 6 0 Q14246-5;Q14246-2;Q14246-3;Q14246;Q8IX30;Q8IX30-2 Q14246-5 EMR1;SCUBE3 EGF-like module-containing mucin-like hormone receptor-like 1;Signal peptide, CUB and EGF-like domain-containing protein 3 0 128.82 6.4818e-07 0.0 59812.0 75575.0 85513.0 92511.0 93794.0 102210.0 75308.0 102290.0 82821.0 96276.0 False True 78830.97183311426 100003.14080032527 84379.04174679836 71184.01823070226 80772.32210228943 95818.79254233872 82010.26610907311 86483.43089036025 87198.7489775775 92905.40654413367 0.8485079046036627 1.076397429602979 0.9082253109426419 0.7661988777465507 0.8694038926993926 1.0313586270872306 0.8827286716636351 0.9308761901738977 0.9385756138546654 1.0 16.50347493490279 DIDEVSSLLR ddPTM_PC-9_AZD4547_30min_R2 4 DIDEVSSLLR 10 0 P50990-2;P50990;P50990-3;H7C4C8 P50990-2 CCT8 T-complex protein 1 subunit theta 0 ;;; 179.37 0.00054598 10107500.0 36327.2 40646.0 47470.7 64813.0 53518.0 46877.6 42209.2 49561.0 44539.8 47805.3 False True 47878.49394729996 53784.02462414843 46841.207501195626 49871.364200867974 46087.94948792375 43946.3362614494 45965.7370299448 41902.48624848116 46894.08289819614 46131.650997800854 1.0378664737054908 1.1658812000184509 1.0153811209451098 1.081066103687583 0.9990526783903922 0.9526287334382282 0.9964034678085993 0.9083240105687675 1.0165273057413797 1.0 15.493469305244084 -6.346689836225211 2.53319526495933 0.9698618440200958 1.0798134884773187 0.5110082784043009 0.04622485898065746 0.2178873772629782 2.7371964028606297 0.014773499688965384 0.01765250131391993 4.5010119272090924e-07 6.346689836225211 0.10995164445722294 DIDEVSSLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DIDEVSSLLR 10 0 P50990-2;P50990;P50990-3;H7C4C8 P50990-2 CCT8 T-complex protein 1 subunit theta 0 ;;; 166.09 0.0012758 7458400.0 29029.300000000003 33682.3 32533.899999999998 29947.6 40381.5 37977.3 37480.2 35266.8 31990.2 28451.7 False True 33943.38713519007 37026.05614543418 33309.63156150282 28269.73306342918 32469.034956023228 35985.70353278425 33929.80412285059 34341.08386826334 32457.996155487534 33609.76798646671 1.009926255630735 1.1016456930123133 0.9910699643899732 0.8411165788116197 0.9660594791697816 1.0706918163575017 1.0095221167998765 1.0217590279733886 0.9657310389216924 1.0 15.03659296307816 DIDEVSSLLR ddPTM_PC-9_Lapatinib_30min_R1 4 DIDEVSSLLR 10 0 P50990-2;P50990;P50990-3;H7C4C8 P50990-2 CCT8 T-complex protein 1 subunit theta 0 ;;; 183.43 0.0022914999999999997 19015300.0 45907.5 51406.0 54012.0 48482.1 55654.0 52633.0 54739.0 49012.1 52629.0 44131.2 False True 45252.85063159557 51286.972565375254 49571.341852349324 52047.635365544455 52380.541139973924 50382.009283515574 57573.117580015954 51289.38109346781 46701.36781206084 51759.21911887227 0.8742954666233677 0.9908760881339335 0.9577297087597442 1.0055722681211592 1.0120040841357112 0.9733919897015111 1.1123258534444125 0.9909226214498057 0.9022811512052497 1.0 15.65952823138859 -3.8108563650163525 1.2001515299967267 1.0006993534967148 3.3477847135377442e-09 0.3326244803186308 0.05005431076053043 15.72255689259489 3.2301114284114867 0.015155117553005092 33.828122339272106 0.00015457655887996614 3.8108563650163525 -1.00069935014893 DIDHETVVEEQIIGENS(ph)PPDYSEYMTGK ddPTM_PC-9_AZD4547_30min_R2 1 DIDHETVVEEQIIGENSPPDYSEYMTGK 28 0 A0A494C032;H0YJU4;H0YJV7;P25490 A0A494C032 YY1 Transcriptional repressor protein YY1 1 DIDHETVVEEQIIGENS(0.997)PPDY(0.002)S(0.001)EYMTGK 95.834 5.642e-05 0.0 6351.5 5654.1 9731.6 10432.0 11416.0 7829.1 7302.7 8280.0 5891.3 9796.2 True False 8371.144880592936 7481.677253048215 9602.552625485518 8027.063572793342 9831.085454503851 7339.545139352559 7952.626152795547 7000.516255471523 6202.702090672678 9453.238019731214 0.8855320116895729 0.7914406933827467 1.0157950752369345 0.8491337630596947 1.0399701598525264 0.7764054098747051 0.8412594855007857 0.7405416261454264 0.6561457648401665 1.0 13.20659286530336 -6.825062016612465 24.999997570795085 0.7890531125371886 0.9112236708891893 0.21477729760045672 0.10666580281101778 92.06954326814075 36176.811082729415 0.03632467978429711 0.032035366139192646 1.4960220111005876e-07 6.825062016612465 0.12217055835200075 DIDIHEVR ddPTM_PC-9_AZD4547_30min_R2 3 DIDIHEVR 8 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PRZ7;A0A1W2PQ74;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 ;; 116.37 0.0030156999999999996 64408900.0 663121.0 469869.0 930471.0 949039.0 835027.0 790838.0 911770.0 1120532.0 768745.0 876977.0 False True 873979.6842263488 621744.9654609066 918132.346581049 730252.721056386 719097.9146652042 741386.7748419754 992915.763667464 947379.5266637723 809379.291275978 846274.3021610256 1.0327380637632213 0.7346849170218612 1.0849110557138844 0.8629031026838819 0.8497220260959516 0.8760596569561289 1.1732788779382504 1.1194709850512616 0.9564030116584736 1.0 19.690765833084598 -7.24473011645895 24.50959239172079 1.072244138072639 0.9025126067077256 0.33420445537505306 0.10701696317928465 665.635218050048 976372.7854693857 0.03948111973695151 0.03049195121417672 5.692065428785417e-08 7.24473011645895 -0.16973153136491348 DIDIHEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DIDIHEVR 8 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PRZ7;A0A1W2PQ74;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 ;;;;; 116.37 0.0030156999999999996 55885800.0 789029.0 766045.0 871808.0 930551.0 1104648.0 863557.0 939025.0 871047.0 828546.0 655616.0 False True 922596.0256668909 842092.8849849663 892595.209070253 878415.2443570467 888200.15418202 818270.5507147834 850073.7540477297 848182.9392005826 840661.9177949671 774473.9909466004 1.1912550149544059 1.0873094446408957 1.1525179922172453 1.134208836740152 1.1468431019825698 1.0565500717650345 1.0976143343545048 1.0951729162187762 1.0854617813149134 1.0 19.562857264436268 -14.522878745280323 0.06572064827177435 0.5705226403165854 1.2782786070347987 0.6668840874751019 0.029721969111046714 211.15451310220502 1.0018250559468354 13.900576733037305 1.951061232664517 3.0000000000000992e-15 14.522878745280323 0.7077559667182133 DIDIHEVR ddPTM_PC-9_Lapatinib_30min_R1 5 DIDIHEVR 8 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PRZ7;A0A1W2PQ74;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 ;;;; 143.73 0.0014398 76577200.0 989044.0 1040437.0 1223707.0 1110589.0 891932.0 1096809.0 899050.0 825462.0 1206188.0 822599.0 False True 974940.0511915463 1038027.9320507577 1123098.5341056196 1192265.4198762954 839470.3133657821 1049901.0358566577 945598.4099145643 863815.9780171865 1070334.4057172667 964784.1411057331 1.0105266138331974 1.075917283280673 1.1640930714495819 1.235784637286686 0.8701120567795304 1.088223770607768 0.9801139650065349 0.8953463694243278 1.1094029846827325 1.0 19.879846667188744 -6.260087184526521 24.999984022460964 0.9896640796698154 1.1213553644462455 0.3494928963398477 0.087582070003649 143.5296228115888 2653643.661854004 0.026515539589950794 0.032396645261929986 5.494305647146325e-07 6.260087184526521 0.1316912847764301 DIDIS(ph)SPEFK ddPTM_PC-9_AZD4547_30min_R2 3 DIDISSPEFK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 DIDIS(0.5)S(0.5)PEFK;DIDIS(0.5)S(0.5)PEFK;DIDIS(0.5)S(0.5)PEFK 170.4 0.00012842 86861000.0 245248.0 271386.0 280729.0 331935.0 317462.0 343969.0 296531.0 332983.0 293105.0 303051.0 True False 323231.7625247033 359106.21725751937 277006.35003492987 255412.5140946282 273387.88109300146 322460.5640543563 322921.68454333633 281528.1285381248 308597.9319142831 292441.27673154604 1.1052877560147645 1.2279600926074814 0.9472204236381273 0.8733805191566396 0.9348471055403197 1.1026506506137546 1.1042274474809197 0.962682599681579 1.0552475196501363 1.0 18.15778742982129 -5.263792635869213 24.999867317906887 0.9970913240840081 1.166623928561582 0.4479110947646071 0.07509031819258058 188.84344359417284 2006206.8378226375 0.02148246962446697 0.048426503869890544 5.447627005385366e-06 5.263792635869213 0.1695326044775739 DIDIS(ph)SPEFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DIDISSPEFK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 DIDIS(0.5)S(0.5)PEFK;DIDIS(0.5)S(0.5)PEFK;DIDIS(0.658)S(0.342)PEFK;DIDIS(0.722)S(0.278)PEFK;DIDIS(0.5)S(0.5)PEFK;DIDIS(0.756)S(0.244)PEFK 226.33 3.021e-12 207931400.0 1082477.0 1042776.0 956765.0 1194049.0 1424651.0 1136331.0 1341830.0 1196308.0 1096310.0 1059075.0 True False 1265718.9762047038 1146295.9098134988 979577.9061514679 1127150.3056890878 1145500.8634927769 1076739.8019636027 1214722.1483920745 1164906.1825930981 1112341.4597352478 1251076.913866915 1.0117035668834558 0.9162473522674542 0.7829877566229887 0.9009440532358748 0.9156118627048945 0.8606503645211875 0.9709412226603457 0.9311227548692634 0.889107174312046 1.0 20.25473905574509 -7.265129231940059 24.95681056695338 0.9420530160346053 0.8945557227318884 0.13956941972192738 0.05948984480141968 735.2394950732877 4972859.016438978 0.024987073604311755 0.017635736495842536 5.4308870187743885e-08 7.265129231940059 -0.0474972933027169 DIDIS(ph)SPEFK ddPTM_PC-9_Lapatinib_30min_R1 3 DIDISSPEFK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 DIDIS(0.673)S(0.327)PEFK;DIDIS(0.5)S(0.5)PEFK;DIDIS(0.5)S(0.5)PEFK 179.19 0.00011643 167182200.0 1049163.0 1168401.0 965584.0 963095.0 1025037.0 953622.0 926566.0 931067.0 1012684.0 805523.0 True False 1034201.74322707 1165695.639270843 886197.4107820273 1033924.2190907389 964746.3389602791 912837.8100614565 974539.0537577424 974327.7718471921 898624.863884722 944756.5772580687 1.0946753567237335 1.2338581887982165 0.9380166617669966 1.0943816047213537 1.021158637244131 0.9662148240457359 1.031523968413229 1.0313003320653735 0.9511707941666486 1.0 19.84958313179034 -5.261177181201598 24.999997862821086 1.0087814223077762 1.1642667744358974 0.5896412990663813 0.05329776630419946 14.533207813586955 1385539.3745225086 0.013051285211590742 0.03049286444392739 5.480533273616232e-06 5.261177181201598 0.1554853521281212 DIDISS(ph)PEFK ddPTM_PC-9_AZD4547_30min_R2 3 DIDISSPEFK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 DIDIS(0.009)S(0.991)PEFK;DIDIS(0.378)S(0.622)PEFK;DIDIS(0.056)S(0.944)PEFK 222.2 1.1015e-08 382549400.0 1718770.0 1865350.0 1768361.0 2171029.0 2106879.0 2128801.0 1922165.0 2138493.0 1958806.0 2086582.0 True False 2265303.107363093 2468287.908592612 1744911.3777134484 1670531.8061136839 1814375.2182287718 1995686.736942799 2093233.9612729896 1808038.0445304387 2062344.4861782917 2013531.3992861356 1.1250398718223213 1.2258502199010668 0.8665925837223487 0.8296527219321951 0.9010910973983464 0.9911376289688539 1.0395834711170193 0.8979438041897181 1.02424252579794 1.0 20.94129653936855 -5.258091249971681 24.996791266718493 0.9396478635873107 1.1754450611423057 0.6354676129460869 0.0701285937126741 180.58515794031726 1348213.3785539235 0.019202751524789653 0.04666618005373563 5.519614540200924e-06 5.258091249971681 0.23579719755499506 DIDISS(ph)PEFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DIDISSPEFK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 DIDIS(0.454)S(0.546)PEFK;DIDIS(0.07)S(0.93)PEFK;DIDIS(0.203)S(0.797)PEFK 207.95 4.4796e-05 187369200.0 704200.0 715232.0 654902.0 829720.0 916358.0 690179.0 861351.0 799802.0 684421.0 690376.0 True False 823407.1514160134 786235.5061563855 670517.3474096656 783233.478388535 736804.2280309452 653984.7982493102 779757.5976387927 778808.0449602682 694429.3623276774 815535.7037865903 1.0096518737228493 0.9640724526294044 0.82218024826676 0.9603914025491788 0.9034604182378659 0.8019082367734636 0.9561293196831515 0.9549649896923054 0.8515008712719658 1.0 19.63738851329709 -5.011776577495086 20.896886072911556 0.9038237607327116 0.9982574901134544 0.22955775417129543 0.06141754619563763 80.41488887214321 142713.16223419207 0.01497237700561778 0.045525685901976115 9.732477816785703e-06 5.011776577495086 0.09443372938074279 DIDISS(ph)PEFK ddPTM_PC-9_Lapatinib_30min_R1 4 DIDISSPEFK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 DIDIS(0.275)S(0.725)PEFK;DIDIS(0.329)S(0.671)PEFK;DIDIS(0.245)S(0.755)PEFK;DIDIS(0.102)S(0.898)PEFK 208.17 7.806100000000001e-09 149922000.0 1212360.0 1299518.0 1107614.0 1120304.0 1181178.0 1106768.0 1045522.0 1100801.0 1166424.0 983226.0 True False 1195071.5240804034 1296509.0459131454 1016550.2524336837 1202694.8933845907 1111703.4323252963 1059434.1126422212 1099654.0133815655 1151948.2331316215 1035049.0461307514 1153175.3040337064 1.0363311804373088 1.124294841710597 0.8815227388913722 1.042941944019846 0.9640368020687357 0.9187103720799545 0.9535878972911332 0.9989359198919776 0.8975643534077085 1.0 20.137180415388947 -5.2516166535740325 24.997789787074474 0.9589326069559188 1.080313014528367 0.4859338093012867 0.05063987865102695 541.5220843993067 1378108.733007211 0.012197020184464741 0.031443987461789905 5.60251910810109e-06 5.2516166535740325 0.12138040757244828 DIDNNLITS(ph)TPR ddPTM_PC-9_Lapatinib_30min_R1 1 DIDNNLITSTPR 12 0 Q05D32;H0YMH7;Q05D32-2;H0YNU2;H0YNW9 Q05D32 CTDSPL2 CTD small phosphatase-like protein 2 1 DIDNNLIT(0.01)S(0.684)T(0.306)PR 109.15 0.0013474000000000001 9852300.0 61986.0 59343.0 61005.0 52201.0 54929.0 46844.0 41910.0 37666.0 55652.0 36652.0 True False 61102.06827315976 59205.59492952303 55989.404386109934 56040.03567743123 51698.18421456905 44840.59131869747 44079.894732795074 39416.099866493336 49383.88571845963 42987.249364279865 1.421399814521102 1.3772827013844657 1.302465387158132 1.3036432083044034 1.2026399683420432 1.0431137600527107 1.025417894484385 0.9169253778597436 1.148803109032955 1.0 15.391621178740838 -6.441520570780246 1.2168053837693176 1.0086964542569186 1.378684459715806 0.8716012121005304 0.05919107220011177 0.14710967006179723 0.4527397978662819 0.02529692325048491 0.03089001576946941 3.6180905288910903e-07 6.441520570780246 0.36998800545888755 DIDNNLITST(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 DIDNNLITSTPR 12 0 Q05D32;H0YMH7;Q05D32-2;H0YNU2;H0YNW9 Q05D32 CTDSPL2 CTD small phosphatase-like protein 2 1 DIDNNLITS(0.029)T(0.97)PR;DIDNNLITS(0.026)T(0.974)PR 163.33 0.00020979 20729000.0 105645.0 112841.0 113790.0 142071.0 150565.0 155584.0 110285.0 157581.0 100165.0 149376.0 True False 139237.91244749152 149314.6465239763 112281.07025093466 109318.72592506939 129661.64869108028 145855.30788481832 120100.15134964572 133230.47730114203 105459.51740909954 144146.3917065159 0.9659479560957855 1.0358542087406741 0.778937779306613 0.7583868359857656 0.899513662160016 1.0118554211317465 0.833181808630849 0.9242720245984456 0.7316139943607928 1.0 17.137175197969114 -5.247321876799351 24.867459349962655 0.8657319387635349 1.0009010946178711 0.25272106869731004 0.09192111514901857 1032.8287901903104 1819281.8037708423 0.023540136936120386 0.06162392534582064 5.658197769935989e-06 5.247321876799351 0.1351691558543362 DIDNNLITST(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DIDNNLITSTPR 12 0 Q05D32;H0YMH7;Q05D32-2;H0YNU2;H0YNW9 Q05D32 CTDSPL2 CTD small phosphatase-like protein 2 1 DIDNNLIT(0.028)S(0.209)T(0.763)PR;DIDNNLITS(0.004)T(0.996)PR;DIDNNLITS(0.023)T(0.977)PR 168.0 0.0017277000000000002 16491100.0 109739.0 100325.0 123111.0 105919.0 131670.0 107575.0 105633.0 87951.0 87777.0 81652.0 True False 128315.6452559528 110284.60297517324 126046.43314106738 99984.70182403113 105870.2087010038 101933.57762503573 95626.67752330763 85642.37944178756 89060.57256723076 96454.86124312371 1.3303180741976388 1.1433804533416967 1.306791918173572 1.0365957768785765 1.0976140272924948 1.0568008321333062 0.991413768998863 0.887901121187845 0.9233393881801878 1.0 16.557566330261487 -6.1394667396639 0.5981606780272268 0.9281045506375926 1.3069360431914503 0.7525949083413715 0.06971892820092114 0.512616907436997 0.364191553463406 0.04706251275521926 0.10937698455993124 7.253260248794525e-07 6.1394667396639 0.37883149255385773 DIDNNLITST(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 DIDNNLITSTPR 12 0 Q05D32;H0YMH7;Q05D32-2;H0YNU2;H0YNW9 Q05D32 CTDSPL2 CTD small phosphatase-like protein 2 1 DIDNNLIT(0.003)S(0.022)T(0.975)PR 159.0 0.00051612 9701500.0 125770.0 107140.0 126810.0 115930.0 112320.0 101810.0 92606.0 81439.0 113390.0 67790.0 True False 123976.49673660674 106891.92391266197 116384.17130075578 124455.87893114329 105713.5584296163 97455.82363070156 97400.6855553619 85222.95324768622 100618.82415036536 79507.41117550302 1.5593074268629321 1.344427171408096 1.463815379975733 1.565336829499101 1.3296063457061427 1.2257451499153909 1.225051653868614 1.0718869095054149 1.2655276113601717 1.0 16.278801725076086 -6.7251973243149585 1.7373909399841438 1.14661719610784 1.4726711839129685 0.7401547455469005 0.09139006788547989 0.18670108868179908 1.1654587262303873 0.0368857090032986 0.03459873392823732 1.8827934365751657e-07 6.7251973243149585 0.3260539878051285 DIDPQNDLTFLR ddPTM_PC-9_AZD4547_30min_R2 1 DIDPQNDLTFLR 12 0 Q9NP97;Q8TF09;H3BQI1;B1AKR6 Q9NP97 DYNLRB1;DYNLRB2 Dynein light chain roadblock-type 1;Dynein light chain roadblock-type 2 0 124.6 0.0014636 1989600.0 7015.4 8001.6 8602.0 12270.0 8895.3 9055.6 8617.2 10954.0 7696.1 8680.2 False True 9246.151270615073 10587.960720183684 8487.931859553046 9441.341069610267 7660.341139054673 8489.351900463795 9384.11410627163 9261.310997878632 8102.900134100455 8376.308840047259 1.1038455538326244 1.2640365729547225 1.013326039146517 1.12714815677176 0.9145246773173484 1.0134955697760422 1.1203161542236886 1.1056553876810469 0.9673592854361299 1.0 13.032098921031862 -5.2753612317539815 24.912722763647576 1.0380934154780779 1.1839410670576194 0.3978232574478128 0.0741813121385362 664.6364599651484 1189346.3865448579 0.019349574743556048 0.040627004544832875 5.30443055739728e-06 5.2753612317539815 0.1458476515795415 DIDPQNDLTFLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DIDPQNDLTFLR 12 0 Q9NP97;Q8TF09;H3BQI1;B1AKR6 Q9NP97 DYNLRB1;DYNLRB2 Dynein light chain roadblock-type 1;Dynein light chain roadblock-type 2 0 90.82700000000001 0.035332 0.0 7772.2 6262.2 8157.3 8768.2 5775.8 7116.8 7484.3 6871.6 5859.4 3906.8 False True 9087.879952052726 6883.869830561985 8351.80096873252 8276.946180887951 4644.073451927222 6743.582479589624 6775.332922360358 6691.227781062032 5945.082640104264 4615.071913788217 1.9691740717845212 1.4916061892763566 1.809679485985964 1.79345984970664 1.0062840923566887 1.4612085370635641 1.4680882657793561 1.4498642504510035 1.2881885160537676 1.0 12.172137413325617 -1.5228787452875427 0.11812198730029295 0.8824309841386083 3.9012376099157238 0.5414450763543268 0.20750310502996427 83.76660885188319 0.6847956743693444 1.573895699443381 41.51201403779652 0.029999999999502282 1.5228787452875427 3.0188066257771156 DIDPQNDLTFLR ddPTM_PC-9_Lapatinib_30min_R1 1 DIDPQNDLTFLR 12 0 Q9NP97;Q8TF09;H3BQI1;B1AKR6 Q9NP97 DYNLRB1;DYNLRB2 Dynein light chain roadblock-type 1;Dynein light chain roadblock-type 2 0 174.77 0.0050236000000000005 3767000.0 13279.0 13298.0 14432.0 14157.0 17016.0 12088.0 14879.0 14141.0 12404.0 13986.0 False True 13089.639024929644 13267.209298026677 13245.456669131032 15198.153006367573 16015.15233474316 11571.024418504283 15649.361816493873 14798.04248425854 11006.930900089355 16403.461464826432 0.797980295378354 0.8088054662410888 0.807479366323563 0.9265210906220388 0.9763276104305232 0.7054013839283718 0.9540280171993235 0.9021292558274755 0.6710126959295308 1.0 14.001712664588016 -12.03481914051888 2.3420985348609364 3.4517608730444906 0.8449925851151554 0.19725541268103985 0.0968146306969118 10047007.525931006 949684.8596661893 133786688.3552891 0.023623987706382164 9.229557068185933e-13 12.03481914051888 -2.6067682879293352 DIDTHTHR ddPTM_PC-9_AZD4547_30min_R2 2 DIDTHTHR 8 0 A0A0A0MSJ0;Q86XP3-2;Q86XP3 A0A0A0MSJ0 DDX42 ATP-dependent RNA helicase DDX42 0 ; 158.07 3.0966e-05 4767600.0 52652.0 46938.0 68743.0 97999.0 82978.0 75874.0 59784.0 64904.0 62970.0 70764.0 False True 69394.24077036604 62109.79057738229 67831.42290412173 75406.84461945704 71457.93700453924 71129.58678561205 65104.66018304588 54874.57814554633 66298.465644197 68286.57389888517 1.0162208587755632 0.9095461527964619 0.9933346927693665 1.1042704343479754 1.0464419713068347 1.0416335558280703 0.9534035237944303 0.8035924928200593 0.9708858104723186 1.0 16.059314331804835 -7.51726327117116 24.8546222886938 0.9080430957396118 1.0159572296622645 0.2847023157634342 0.06673693786982463 278.22838508105445 1231484.1652537 0.031471498909341505 0.0188926678180917 3.039042186801418e-08 7.51726327117116 0.1079141339226527 DIDTHTHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DIDTHTHR 8 0 A0A0A0MSJ0;Q86XP3-2;Q86XP3 A0A0A0MSJ0 DDX42 ATP-dependent RNA helicase DDX42 0 ;; 128.38 0.0031006000000000002 4291900.0 47547.2 47959.7 51069.0 60439.0 63836.0 58393.0 51864.7 58388.7 52743.0 45049.2 False True 55596.00185999347 52720.82206138474 52286.67864026104 57052.798775881776 51327.7940505603 55330.76828499844 46951.70014808912 56856.05849294143 53514.26659504718 53216.26335072904 1.0447182564018154 0.9906900398835028 0.9825319432080106 1.0720932884721261 0.9645133051202313 1.0397341865274055 0.8822810395131943 1.0683962930321476 1.0055998528561487 1.0 15.699579592753796 DIDTHTHR ddPTM_PC-9_Lapatinib_30min_R1 4 DIDTHTHR 8 0 A0A0A0MSJ0;Q86XP3-2;Q86XP3 A0A0A0MSJ0 DDX42 ATP-dependent RNA helicase DDX42 0 ;;; 129.42 0.0031769000000000003 4629700.0 75310.3 66091.2 72164.7 63941.4 66431.2 69054.6 57679.9 65652.7 75090.5 55457.0 False True 74236.36131178253 65938.16988703115 66231.59692979774 68643.86385825743 62523.8474247643 66101.2957321349 60666.28299208179 68703.16411896495 66633.01715197996 65042.668558192396 1.1413486401678725 1.0137679057254172 1.0182792065264301 1.0553666597618627 0.9612743266956436 1.016275887773506 0.9327151597078902 1.0562783729806162 1.0244508509420198 1.0 15.989098828793457 DIEDVFYK ddPTM_PC-9_Lapatinib_30min_R1 2 DIEDVFYK 8 0 J3KTL2;Q07955;Q07955-3;Q07955-2;J3QQV5;J3KSW7 J3KTL2 SRSF1 Serine/arginine-rich splicing factor 1 0 ; 95.531 0.029480000000000003 6535700.0 43531.0 44023.0 49743.0 51462.0 49385.0 45488.0 42416.0 47972.0 39305.0 48322.0 False True 42910.23995739228 43921.06744826509 45653.322553532795 55246.6871521995 46480.27139464566 43542.584277707065 44612.092936918074 50200.95425039608 34878.057000000976 56674.39331498232 0.7571362911448868 0.7749719913923491 0.8055370315091486 0.9748086202732161 0.8201282568005581 0.7682937872084153 0.7871648963046688 0.8857784144488594 0.6154112106001263 1.0 15.790409421913374 -5.321060158498775 4.291829933066162 0.8296029897144809 0.7651239516092472 0.0646156849116396 0.10257187533356783 0.6529088868470493 24.55404591503307 0.026494455853127884 0.061052345963631724 4.774631308540183e-06 5.321060158498775 -0.0644790381052337 DIEEHLQR ddPTM_PC-9_AZD4547_30min_R2 1 DIEEHLQR 8 0 Q9UNE7;Q9UNE7-2;H3BTA3 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 0 124.08 0.0027843000000000004 6112500.0 58911.0 71438.0 72262.0 96265.0 99909.0 90334.0 58800.0 82346.0 86578.0 76746.0 False True 77643.47257507825 94528.93645376951 71303.75866484789 74072.59152942407 86038.35990487262 84685.4006997325 64033.08608930647 69621.31782283299 91154.3363275098 74059.14589966423 1.0483981638172022 1.2763978750421705 0.9627947743476631 1.0001815525901157 1.1617519870056008 1.1434833560525366 0.8646209095640783 0.9400772447086598 1.2308315903481553 1.0 16.17639029101654 DIEEHLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DIEEHLQR 8 0 Q9UNE7;Q9UNE7-2;H3BTA3 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 0 ; 158.07 3.0966e-05 7479500.0 104777.0 108737.0 106558.0 115666.0 137775.0 123686.0 118853.0 104742.0 101982.0 99687.0 False True 122513.67665991967 119531.69074220199 109098.74684346528 109185.60901423154 110778.97777611284 117199.68842324098 107594.38341879612 101992.63348332245 103473.29381901087 117759.46397814195 1.0403722343934936 1.0150495484964928 0.9264541732604673 0.9271917969539852 0.9407225036000095 0.9952464495337302 0.9136792898341263 0.8661098652950214 0.8786834647805222 1.0 16.845483484046987 -5.194169929877544 3.5951142446197224 0.9277364310570595 1.0352617953780827 0.47861582329827423 0.0405569615131634 0.20891517306782184 5.281838538409696 0.011326024120755753 0.034554402289929016 6.394845702786702e-06 5.194169929877544 0.10752536432102322 DIELVMSQANVSR ddPTM_PC-9_Lapatinib_30min_R1 1 DIELVMSQANVSR 13 0 E9PAV3;F8VZJ2;F8W0W4;H0YHX9;Q13765;E9PAV3-2 E9PAV3 NACA Nascent polypeptide-associated complex subunit alpha, muscle-specific form;Nascent polypeptide-associated complex subunit alpha 0 120.03 0.0010081 6247900.0 13039.0 8942.2 12186.0 14812.0 15872.0 11205.0 11098.0 7786.1 14687.0 13303.0 False True 12853.061468940246 8921.494885307127 11184.114119320317 15901.323891383516 14938.440165552618 10725.788270130752 11672.600137068948 8147.870630555513 13032.795399033579 15602.405824866717 0.8237871526489436 0.5718025146537514 0.7168198446354574 1.0191584599113805 0.9574446616267417 0.6874445127581712 0.7481282225376714 0.5222188630403168 0.835306781872206 1.0 13.929480883251964 -5.5405111211627895 24.986134762512187 0.8061661115361571 0.6844237896927445 0.1053421195415799 0.15390472643810385 557.5537578984964 790084.1997975494 0.04426416076944986 0.07668695640263633 2.880639283080037e-06 5.5405111211627895 -0.1217423218434126 DIERDS(ph)RES(ph)AS(ph)SR ddPTM_PC-9_AZD4547_30min_R2 1 DIERDSRESASSR 13 2 Q2M3C7-2;Q2M3C7 Q2M3C7-2 SPHKAP A-kinase anchor protein SPHKAP 3 DIERDS(1)RES(0.982)AS(0.596)S(0.423)R 116.58 0.0032925 1284700.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DIEREDIEFICK ddPTM_PC-9_AZD4547_30min_R2 2 DIEREDIEFICK 12 1 P50991;P50991-2 P50991 CCT4 T-complex protein 1 subunit delta 0 ; 143.31 0.00010896 7573000.0 29300.0 28519.0 34243.0 42514.0 38830.0 37369.0 25437.0 39005.0 30496.0 30042.0 False True 38616.7905221401 37737.209030558726 33788.915446021274 32713.054134752318 33439.12475458872 35032.310522597196 27700.843722001504 32977.67349573268 32107.956301182057 28990.23872407313 1.3320618325944726 1.3017212238139393 1.1655273268917026 1.128416169529084 1.1534615176114882 1.2084174558213212 0.9555231326535808 1.1375440474847982 1.1075437014087095 1.0 14.823279593066676 -1.5228787452803378 0.2784022113416029 1.0433456950356945 3.3489408791330195 0.6719611945461059 0.0634087139643095 31.651368409917648 0.4455475987539728 0.07174102520754175 35.42856954615997 0.02999999999999998 1.5228787452803378 2.3055951840973252 DIEREDIEFICK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DIEREDIEFICK 12 1 P50991;P50991-2 P50991 CCT4 T-complex protein 1 subunit delta 0 108.35 0.0018701 3387300.0 16990.0 19882.0 19514.0 24133.0 24671.0 22596.0 18981.0 19840.0 22760.0 17577.0 False True 19866.071432204 21855.75356443955 19979.287767257123 22780.90625024164 19836.894652255345 21411.025982015402 17182.98226946034 19319.221022217636 23092.821942310315 20763.570960544566 0.9567752806082337 1.052600904053083 0.9622279233770648 1.0971574346980324 0.9553700897571947 1.0311822577484935 0.8275542921837411 0.9304382689725424 1.1121796913542399 1.0 14.341766962167902 DIEREDIEFICK ddPTM_PC-9_Lapatinib_30min_R1 2 DIEREDIEFICK 12 1 P50991;P50991-2 P50991 CCT4 T-complex protein 1 subunit delta 0 ; 161.48 0.0005197 9953200.0 38408.0 39184.0 51126.0 47139.0 52684.0 44133.0 41417.0 40531.0 45964.0 43095.0 False True 37860.294876835425 39093.2718554578 46922.61763206717 50605.75931109423 49585.23070072925 42245.534469047794 43561.36960506261 42414.21822569008 40787.05029762234 50543.91332952201 0.7490574508943245 0.7734516241468774 0.9283534760388312 1.001223608887761 0.9810326789985054 0.8358184336386307 0.8618519369694116 0.8391558039673298 0.8069626511051962 1.0 15.625249747879035 -5.216152080988973 6.338760147706384 0.9029202085375607 0.7588786902648245 0.42602182384238274 0.06749569545659656 0.23208178070412944 24.17916754903331 0.01896502574694765 0.05057246090961923 6.079220821999367e-06 5.216152080988973 -0.14404151827273626 DIIDYES(ph)DVEPETKR ddPTM_PC-9_AZD4547_30min_R2 1 DIIDYESDVEPETKR 15 1 F5GYN7;Q5FWF4-2;Q5FWF4-3;Q5FWF4 F5GYN7 ZRANB3 DNA annealing helicase and endonuclease ZRANB3;DNA annealing helicase ZRANB3;Endonuclease ZRANB3 1 DIIDYES(1)DVEPETKR 90.706 0.0018959 2001700.0 5947.4 6599.5 9616.9 11497.0 10009.0 9548.9 9061.9 10203.0 9513.6 10856.0 True False 7838.549486395088 8732.659314743587 9489.37362242916 8846.544276879325 8619.423117916002 8951.80577348145 9868.391544773582 8626.360791615449 10016.469473600662 10475.934744309236 0.7482434434457665 0.833592374130372 0.9058259576868788 0.8444634767971391 0.8227832005729385 0.8545114103869608 0.9420058243618131 0.8234454492284312 0.9561408807974711 1.0 13.35479135768062 -14.522878741549201 0.02227624387513011 2.1557310571079444 3.910036776953153e-08 0.5911848613142385 0.046165014657680165 1967.4894190798075 3.3021984362032053 222.89729647590698 113.6188568893975 3.0000000257737777e-15 14.522878741549201 -2.1557310180075766 DIIDYES(ph)DVEPETKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DIIDYESDVEPETKR 15 1 F5GYN7;Q5FWF4-2;Q5FWF4-3;Q5FWF4 F5GYN7 ZRANB3 DNA annealing helicase and endonuclease ZRANB3;DNA annealing helicase ZRANB3;Endonuclease ZRANB3 1 DIIDYES(1)DVEPETKR 76.051 0.040128 0.0 4742.4 5527.4 5744.7 5946.8 7317.5 7072.5 7554.5 4336.4 6593.6 4531.7 True False 5545.194653330445 6076.123742686006 5881.675434896072 5613.620075785728 5883.688404113273 6701.60564957532 6838.883070156371 4222.574094795592 6690.018926134329 5353.261337082541 1.0358535300562228 1.1350321533148642 1.0987088177730382 1.0486355367894442 1.0990848444772188 1.251873433331691 1.277517131992565 0.788785345775187 1.249709010055598 1.0 12.38620236894396 -9.830362749098303 0.595623085904573 0.9901653707859621 1.1111202559237652 0.048099658175002835 0.1351222927091119 27.277755216411734 8.932970822061183 0.7962783107666576 0.05504713166128242 1.4778734629244898e-10 9.830362749098303 0.12095488513780306 DIIHDPGR ddPTM_PC-9_AZD4547_30min_R2 4 DIIHDPGR 8 0 E9PKU4;P62917;E9PKZ0;G3V1A1 E9PKU4 RPL8 60S ribosomal protein L8 0 ;;; 109.71 0.0031671 91137000.0 370070.0 343644.0 485088.0 626200.0 493819.0 459091.0 442476.0 527810.0 379218.0 461328.0 False True 487744.562065815 454720.20267531544 478655.4161691317 481839.26469355787 425260.755786409 430383.96719552705 481855.50681040675 446249.09236720036 399262.6892911093 445177.047137315 1.0956192939465947 1.0214367645397875 1.0752023700392852 1.082354240390418 0.9552620884680005 0.9667703444350647 1.0823907250136782 1.0024081323077618 0.8968627018363698 1.0 18.764019685187627 -6.254010166542556 24.867084376566876 0.9881325586070716 1.0657483698594739 0.433544543562015 0.047241035851350005 607.870995298291 2034665.4212089044 0.014606556505406576 0.018466426894070385 5.571727057398983e-07 6.254010166542556 0.07761581125240224 DIIHDPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DIIHDPGR 8 0 E9PKU4;P62917;E9PKZ0;G3V1A1 E9PKU4 RPL8 60S ribosomal protein L8 0 ;;;;; 110.41 0.0031578 89683400.0 487997.0 426530.0 537753.0 522789.0 583107.0 494757.0 532384.0 544025.0 472499.0 377363.0 False True 570605.2537199083 468873.0795614332 550575.0709596087 493498.8272348053 468851.3692186232 468811.07195007894 481952.73339362466 529744.9201921336 479408.4039947147 445775.92469613644 1.2800270766279311 1.0518133743562776 1.235093777966831 1.1070558096451693 1.0517646719889957 1.0516742739519735 1.0811546938568928 1.1883659274628497 1.075447051837768 1.0 18.765959176589867 -1.5229008454832602 0.8375992349929172 1.09169471147769 52.269090904342114 0.3629850632624715 0.06910288434856279 771.1468685862062 2.268610937957307 0.023914713250268584 75129.63139101054 0.0299984734109085 1.5229008454832602 51.17739619286442 DIIHDPGR ddPTM_PC-9_Lapatinib_30min_R1 4 DIIHDPGR 8 0 E9PKU4;P62917;E9PKZ0;G3V1A1 E9PKU4 RPL8 60S ribosomal protein L8 0 ;;; 91.318 0.0073982 104145000.0 367803.0 362719.0 389143.0 339242.0 369715.0 350773.0 340259.0 343027.0 377670.0 296288.0 False True 362558.06177319057 361879.1464408887 357149.1646754191 364190.98835813696 347969.0905876564 335771.25648180087 357875.94611992635 358965.2867016308 335132.8275585903 347500.98602105654 1.0433295914481855 1.0413758838052936 1.0277644641093995 1.0480286474239504 1.0013470596787646 0.9662454783983119 1.0298559155692328 1.032990699715251 0.9644082780768949 1.0 18.406657545872008 -6.270555104046346 23.550516132124972 1.0006817145438816 1.0393311506806373 0.4645459096742528 0.021510769109987254 293.80793792465454 759051.4050598403 0.006805621070561652 0.007832569370646759 5.36345814624193e-07 6.270555104046346 0.038649436136755755 DIIIFVGT(ph)PVQK ddPTM_PC-9_AZD4547_30min_R2 1 DIIIFVGTPVQK 12 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 DIIIFVGT(1)PVQK 76.24 0.04614 2622300.0 24369.0 32858.0 28034.0 26666.0 25791.0 36126.0 26036.0 42381.0 33908.0 25995.0 True False 32117.835093311693 43478.7059267891 27662.250842909787 20518.565685593116 22210.364835065593 33867.03550909435 28353.15356158474 35831.990268495 35700.30765544602 25084.922962262197 1.2803641112085462 1.7332604924559085 1.102744101886417 0.8179640701492799 0.8854069382026369 1.3500952568219555 1.130286650839601 1.4284273594302326 1.4231778869384462 1.0 14.614532887030453 -5.281327768463765 24.617387586901973 1.1438030875227678 1.5068123180740194 0.2985002219211217 0.22353139168991848 770.1776260710275 953307.3886503681 0.06316346418923348 0.13177870601869554 5.232054166805983e-06 5.281327768463765 0.36300923055125156 DIIIFVGT(ph)PVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DIIIFVGTPVQK 12 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 DIIIFVGT(1)PVQK;DIIIFVGT(1)PVQK 150.26 0.00042166 4868200.0 46027.0 81506.0 59409.0 40682.0 54737.0 33748.0 54446.0 23975.0 28434.0 29858.0 True False 53818.46202531212 89597.37702561147 60825.53586988718 38402.719432823535 44011.677782842264 31978.19547004142 49288.48072509546 23345.681653612286 28849.79345815692 35271.019044202054 1.5258550357693434 2.5402548452974094 1.7245188122764445 1.0887896203026286 1.2478141821671302 0.9066422331026492 1.3974215109386707 0.6618941637142721 0.8179461280095713 1.0 15.106195638012185 -5.678407907213094 3.255395825925798 1.0159800998423656 2.0554309062429237 0.6664057198359752 0.3006603795256647 0.13222775870415135 2.7801861165892725 0.0826594919230691 0.15183948495953947 2.096969398610236e-06 5.678407907213094 1.039450806400558 DIIIFVGT(ph)PVQK ddPTM_PC-9_Lapatinib_30min_R1 2 DIIIFVGTPVQK 12 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 DIIIFVGT(1)PVQK;DIIIFVGT(1)PVQK 120.29 0.0012219000000000002 4355300.0 39364.0 70410.0 58169.0 50086.0 51303.0 54012.0 55344.0 53803.0 49114.0 41058.0 True False 38802.66214152649 70246.9699709775 53386.56935883339 53769.49152199801 48285.458405578756 51702.03266812156 58209.441519728214 56302.88379750813 43582.26412665179 48154.820593653916 0.8057897768731402 1.4587733710762698 1.1086443413282894 1.1165962381154426 1.0027128709091704 1.073662657875941 1.2087978067848797 1.1692055562330972 0.9050446785881138 1.0 15.555392607492443 -8.260441341457122 24.96894305723861 0.9525223296825504 1.1267245064775302 0.1499888980383658 0.15650188525943715 150.27227235747344 3759790.2669924526 0.11525239165630637 0.037831194606054254 5.489826996542954e-09 8.260441341457122 0.17420217679497985 DIINEEEVQFLK ddPTM_PC-9_Lapatinib_30min_R1 1 DIINEEEVQFLK 12 0 P49588-2;P49588 P49588-2 AARS Alanine--tRNA ligase, cytoplasmic 0 164.13 0.00352 2503700.0 9721.3 14876.0 13300.0 9739.5 12292.0 11464.0 12164.0 12029.0 16540.0 13742.0 False True 9582.67247933192 14841.555535978721 12206.525339484673 10455.775320019558 11569.008727001812 10973.711443889248 12793.792401090896 12587.911254023482 14677.091026078528 16117.286389935984 0.5945586774033853 0.9208470444035878 0.7573561109584004 0.6487305038240427 0.7178012754197739 0.6808659459412159 0.7937932038658594 0.7810192702093867 0.9106428136217305 1.0 13.976321242439298 -8.331424588715466 1.3402910022525782 1.0007738467510594 0.7301829083685192 0.5537487279256611 0.08217539708617712 0.3199561779111028 1.1722579147864576 0.07737036331333413 0.024017998384260414 4.6620337294708775e-09 8.331424588715466 -0.2705909383825402 DIIRQPS(ph)EEEIIK ddPTM_PC-9_AZD4547_30min_R2 1 DIIRQPSEEEIIK 13 1 B1AKZ5;Q15121;Q15121-2 B1AKZ5 PEA15 Astrocytic phosphoprotein PEA-15 1 DIIRQPS(1)EEEIIK 70.45100000000001 0.013294 95718000.0 34602.0 19200.0 42781.0 98512.0 92016.0 45620.0 25955.0 39851.0 32495.0 49997.0 True False 45604.71623368914 25406.02452353615 42213.69598739115 75801.58039522785 79241.16671177532 42767.374188254566 28264.944718502546 33692.9436348787 34212.61936014269 48246.62024790243 0.9452416770203059 0.5265866166996579 0.8749565414217058 1.5711272625054684 1.6424190192932824 0.8864325411501528 0.5858429994323052 0.6983482669201794 0.7091195027620639 1.0 15.558140262399169 -6.994406539307699 24.996244523525785 0.7250396611703693 1.1091257568236779 0.22550466594656837 0.31856505433289956 249.88214901631855 1116673.7929578312 0.12853481669928182 0.11302074565914862 1.0129627161491783e-07 6.994406539307699 0.38408609565330853 DIIRQPS(ph)EEEIIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DIIRQPSEEEIIK 13 1 B1AKZ5;Q15121;Q15121-2 B1AKZ5 PEA15 Astrocytic phosphoprotein PEA-15 1 DIIRQPS(1)EEEIIK;DIIRQPS(1)EEEIIK;DIIRQPS(1)EEEIIK;DIIRQPS(1)EEEIIK;DIIRQPS(1)EEEIIK;DIIRQPS(1)EEEIIK 81.71300000000001 0.0053438 171691000.0 76396.1 32637.9 58765.6 125234.4 111871.2 149496.0 88949.0 146312.0 103335.3 96042.8 True False 89328.45083824598 35877.97501563331 60166.79477377905 118217.92258340264 89950.84143412874 141656.16658733282 80523.10678500742 142471.46503037828 104846.38327131899 113454.5993656135 0.7873497534496621 0.3162320013137116 0.5303160480950477 1.0419843994375149 0.7928355653899704 1.248571387845091 0.7097385847313021 1.2557575085277626 0.9241263365044015 1.0 16.791755570423362 -5.757490861796383 24.91981542281835 0.9969143730096486 0.5217923921141978 0.532394210720611 0.19355529132952998 66.7088631850897 421003.9362881143 0.049571587902644244 0.08193255603307728 1.7478700398237453e-06 5.757490861796383 -0.47512198089545077 DIIRQPS(ph)EEEIIK ddPTM_PC-9_Lapatinib_30min_R1 4 DIIRQPSEEEIIK 13 1 B1AKZ5;Q15121;Q15121-2 B1AKZ5 PEA15 Astrocytic phosphoprotein PEA-15 1 DIIRQPS(1)EEEIIK;DIIRQPS(1)EEEIIK;DIIRQPS(1)EEEIIK;DIIRQPS(1)EEEIIK 122.46 8.5619e-05 156915000.0 196319.0 54555.0 118117.0 98671.0 78154.0 84945.0 59058.0 53839.3 115160.0 93717.0 True False 193519.45505950475 54428.68124934921 108405.87620480514 105927.59449680666 73557.13537667581 81312.1003664665 62115.7342669867 56340.870428027796 102189.46811143901 109915.8585799469 1.7606145060382627 0.49518497105456993 0.9862623792903963 0.9637152988234233 0.6692131265405555 0.7397667763048446 0.565120766643578 0.512581816272203 0.9297063174656628 1.0 16.746040026730107 -4.752455239739536 24.999647604561744 0.7506660761367003 1.7606164473073207 0.7142687592127177 0.18927595904559155 189.2343732641933 526533.0866967457 0.04733466172666627 0.5632271905857523 1.7682544522655997e-05 4.752455239739536 1.0099503711706204 DIISDTSGDFR ddPTM_PC-9_AZD4547_30min_R2 2 DIISDTSGDFR 11 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YN28;H0YNP5;H0YL33;H0YNA0;H0YN52 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ; 110.53 0.0088672 25993000.0 68779.0 109085.0 86703.0 63309.0 68145.0 93365.0 91520.0 113411.0 99468.0 76165.0 False True 90649.29130792765 144344.59297655956 85553.26156926628 48714.08816429962 58684.24301832208 87526.8717905826 99665.10270226744 95885.9358755171 104725.67541205324 73498.48653282183 1.2333490876366124 1.9639124529741216 1.1640139219881924 0.6627903574932202 0.7984415161000052 1.1908663146620875 1.3560157141162428 1.3045974196039782 1.4248684612748652 1.0 16.165426922096096 -7.126425113568073 6.8277293745008025 1.295707456360202 1.1633346129741402 0.02001532808101736 0.337273365142418 1.2839895113943922 65.80238631594537 0.14615643357561628 0.11310326757587058 7.474375055095007e-08 7.126425113568073 -0.1323728433860618 DIISDTSGDFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DIISDTSGDFR 11 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YN28;H0YNP5;H0YL33;H0YNA0;H0YN52 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ; 128.27 0.001467 13507000.0 55307.0 83845.0 67046.0 54851.0 74662.0 45235.0 53948.0 46042.0 41403.0 46340.0 False True 64669.382736957414 92168.57748769932 68644.63091337089 51777.87629934136 60032.517065651555 42862.796968333634 48837.65489030324 44833.44628553143 42008.440548219456 54741.075172761855 1.1813685159245044 1.6837188015912536 1.2539876262336767 0.9458688221948749 1.0966630976134466 0.7830097752566864 0.8921573925278682 0.8190092383833871 0.7674025476416305 1.0 15.740336150590982 -5.691639933625041 2.667993432423812 0.8872649550526338 1.4434852328207 0.691738807456676 0.1473998329108492 0.1388397948026428 1.998837711095935 0.04156892241165679 0.07920370069719176 2.0340427032272305e-06 5.691639933625041 0.5562202777680662 DIISDTSGDFR ddPTM_PC-9_Lapatinib_30min_R1 3 DIISDTSGDFR 11 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YN28;H0YNP5;H0YL33;H0YNA0;H0YN52 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ;; 170.47 0.00054597 68030000.0 294215.0 333899.0 341424.0 325124.0 388147.0 331755.0 424338.0 421096.0 343583.0 340877.0 False True 290019.4401475774 333125.8773801933 313353.4366547536 349034.7035418696 365316.9565863631 317566.6120086775 446308.14533821965 440661.6574465269 304885.06445061276 399797.13525994885 0.7254165039451976 0.8332372796108063 0.7837810955073767 0.8730295261243595 0.9137558135548753 0.79431937850729 1.116336526643767 1.102213144073701 0.7625994224605335 1.0 18.608908608947885 -6.3869181927109215 0.8489624761298299 0.9882814035352188 0.7732785638736801 0.3498792354338509 0.1070257933885531 0.7135863392310344 1.1242236451912893 0.05973956309535253 0.08557494163191277 4.1028137969131363e-07 6.3869181927109215 -0.21500283966153866 DIISDTSGDFRK ddPTM_PC-9_AZD4547_30min_R2 4 DIISDTSGDFRK 12 1 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YN28;H0YNP5;H0YL33;H0YNA0;H0YN52 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ;;; 150.09 0.00010767 47551600.0 149819.0 190920.0 198083.0 152233.0 158386.0 174175.0 174159.0 225482.0 183380.0 186245.0 False True 197458.32557121187 252631.1563559123 195456.28999486714 117138.03382640437 136396.8378413673 163283.80971589743 189658.81360931168 190638.93796089728 193073.0924223103 179724.61923856646 1.0986715476587305 1.4056569290630667 1.0875320856038007 0.6517639838252507 0.7589212786719783 0.9085222180894121 1.0552745328538355 1.060728011379694 1.074271812288694 1.0 17.455428521685292 -5.522798338161568 24.999999919873776 0.9250456646005473 1.2507718451994334 0.4410377863015785 0.14592222433572666 2.5047421815681647 778721.8054353493 0.0431103758812042 0.07568580120619132 3.0005554841199026e-06 5.522798338161568 0.32572618059888614 DIISDTSGDFRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DIISDTSGDFRK 12 1 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YN28;H0YNP5;H0YL33;H0YNA0;H0YN52 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ;;; 152.67 0.00012881 42044000.0 99640.0 115369.0 130852.0 101619.0 126641.0 95111.0 107634.0 91882.0 84063.0 98605.0 False True 116507.08402029444 126822.07187284107 133972.0079389733 95925.6168832433 101826.60515002535 90123.21172665375 97438.12831732204 89470.19485702601 85292.26234342864 116481.30594324958 1.0002213065593326 1.0887761846920705 1.150158876174047 0.8235279996772947 0.8741883886469809 0.7737139534696009 0.8365130140693521 0.7681077588588889 0.732239921700256 1.0 16.829738910114287 -5.771469571349466 24.972374092350616 0.8198914631407546 1.0806245257498206 0.6867441587347662 0.07716192098362835 100.15206313158718 249350.84844339543 0.021034895393416297 0.031615693680166077 1.6925068250233379e-06 5.771469571349466 0.26073306260906604 DIISDTSGDFRK ddPTM_PC-9_Lapatinib_30min_R1 4 DIISDTSGDFRK 12 1 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YN28;H0YNP5;H0YL33;H0YNA0;H0YN52 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ;;; 163.46 0.00046365 79826000.0 197256.0 208646.0 190061.0 162422.0 189817.0 173646.0 185183.0 191026.0 180858.0 172876.0 False True 194443.09326768023 208162.89300617183 174434.91823667675 174367.05570390826 178652.3372545805 166219.56536859678 194770.869632622 199901.7653346988 160487.8675208287 202757.38625720996 0.95899388356199 1.0266599745081773 0.8603135079646151 0.8599788097618952 0.8811138304374728 0.8197953644842179 0.9606104775169246 0.9859160695685403 0.7915266145581507 1.0 17.62939494583398 -5.262068468703484 24.988086916543676 0.8923278056739572 0.9928269312745169 0.25390919954550994 0.0670245498641701 69.91266425267426 2777132.1996428403 0.017100871641986808 0.0394809122678739 5.469297298813127e-06 5.262068468703484 0.10049912560055974 DIISIAEDEDLR ddPTM_PC-9_AZD4547_30min_R2 2 DIISIAEDEDLR 12 0 P12956;B1AHC9;P12956-2 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 ; 196.44 5.7087e-05 7380500.0 20000.1 21321.0 27135.0 26925.0 25995.0 28476.0 23643.0 32963.0 23603.0 27461.0 False True 26359.715772076957 28212.59629512051 26775.17217030597 20717.857237103228 22386.04295636192 26695.391218429126 25747.181197440023 27869.325764384994 24850.606393520477 26499.59874847788 0.9947213171894175 1.0646423956415954 1.01039915450961 0.7818177714216615 0.8447691291041816 1.0073885069660722 0.9716064549437347 1.0516885945673342 0.93777293118251 1.0 14.693682894396465 -9.534679596298648 14.008381537460151 1.0000003082531748 0.9625508096639777 0.017289258127386575 0.08422349122692915 0.0 0.0 0.08994353337945553 0.021814511086162527 2.919580159731061e-10 9.534679596298648 -0.037449498589197106 DIISIAEDEDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DIISIAEDEDLR 12 0 P12956;B1AHC9;P12956-2 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 ;; 203.02 4.9794e-07 4119300.0 13573.900000000001 17365.7 17418.6 16533.9 17869.6 13303.400000000001 16418.9 13975.800000000001 14355.5 10449.099999999999 False True 15871.693173254489 19089.6519300869 17833.92548440835 15607.55918662704 14368.180157996929 12605.746284702767 14863.582929458009 13608.950058584127 14565.422029562209 12343.439114969913 1.2858404392342786 1.5465423981340254 1.4448100985712864 1.2644417039087963 1.1640337854116722 1.0212507363053083 1.2041686916437826 1.1025249877142769 1.180013276194437 1.0 13.591456792096025 -6.022075404444679 2.3000961629896786 1.115199052186227 1.4389339387855409 0.7335330467448945 0.08484371439750432 0.14739904129846151 1.5584000667109394 0.025818118414081034 0.03916858316318762 9.504397590836333e-07 6.022075404444679 0.32373488659931393 DIISIAEDEDLR ddPTM_PC-9_Lapatinib_30min_R1 4 DIISIAEDEDLR 12 0 P12956;B1AHC9;P12956-2 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 ;;; 175.33 0.00029298 11545700.0 31168.9 41430.3 41360.7 34777.399999999994 42286.8 35602.2 37037.3 38302.8 41602.3 36073.1 False True 30724.425770323796 41334.37068582003 37960.18290291909 37335.04601000545 39799.57356304753 34079.57689878171 38954.91016909931 40082.48791924606 36916.61088235952 42308.287270615656 0.7262034876004733 0.9769804771683103 0.8972280692932599 0.8824523141577449 0.9407039644143076 0.8055059445162407 0.9207394740404592 0.9473909369780733 0.8725621684052237 1.0 15.368652663064486 -14.52287874528027 0.11956192295570285 1.3444005470449072 0.8387737528381126 0.23311748160670054 0.06804180208309071 252.74891904178637 1.9540452000063386 21.204303338967417 0.6416294481321609 3.0000000000004672e-15 14.52287874528027 -0.5056267942067946 DILCEFLSNIFQALT(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 DILCEFLSNIFQALTK 16 0 J3KND1;E9PRZ1;Q96ER3 J3KND1 SAAL1 Protein SAAL1 1 DILCEFLS(0.006)NIFQALT(0.994)K 79.652 0.034974 0.0 14909.0 11753.0 17934.0 22412.0 17032.0 22417.0 15500.0 17743.0 17715.0 17949.0 True False 19649.751873535402 15551.927407558342 17696.18344213256 17245.259661948272 14667.400793720195 21015.261446253888 16879.469972521263 15001.22704357864 18651.378734110727 17320.610973250412 1.1344722137043588 0.8978856133641251 1.021683557783393 0.9956496158583256 0.8468177488872778 1.2133094772874593 0.9745308637547233 0.8660911019101012 1.076831456056344 1.0 14.080202200637878 -5.956116565823993 0.002769705877025105 0.21811484314041304 1.7803626518240692 0.0 0.1106407579558855 976516.5090340473 663.2328629673937 184688.59593351145 189413.4998441861 1.1063268029914628e-06 5.956116565823993 1.5622478086836562 DILIQYDR ddPTM_PC-9_AZD4547_30min_R2 3 DILIQYDR 8 0 M0R210;P62249 M0R210 RPS16 40S ribosomal protein S16 0 ;; 107.15 0.017575999999999998 18120400.0 77719.0 87609.0 107226.0 125351.0 107986.0 97113.0 91663.0 125984.0 88311.0 101631.0 False True 102432.02534437552 115926.89596262905 105804.1131797762 96453.26360364434 92994.007874041 91040.50875808777 99820.8294252398 106516.06762431434 92978.9391695203 98072.92962406878 1.04444749164745 1.1820478536431789 1.078830963705708 0.9834850857761371 0.9482128068418451 0.928293965593385 1.0178224491495362 1.086090402648413 0.9480591588925235 1.0 16.5815673540515 -5.657379683607869 4.131801561694628 0.988141150701549 1.1167235213943587 0.5082685199383947 0.052068002235319516 0.17430715843308 5.376801955065253 0.014956723911141334 0.02681860539983966 2.2010013878125954e-06 5.657379683607869 0.12858237069280976 DILIQYDR ddPTM_PC-9_Lapatinib_30min_R1 4 DILIQYDR 8 0 M0R210;P62249 M0R210 RPS16 40S ribosomal protein S16 0 ;;; 110.87 0.017301 34594800.0 152874.0 171471.0 179866.0 151456.0 177645.0 173686.0 186731.0 164652.0 167049.0 154246.0 False True 150693.98872634186 171073.96943464724 165078.11178283853 162594.5794824053 167196.27036350782 166257.85466184124 196399.0174982001 172302.33301167793 148234.18251604543 180907.21558012388 0.8329904821270074 0.9456448096116902 0.9125015343001914 0.8987733239992967 0.9242100699375173 0.9190227936939617 1.0856339636227217 0.9524348294187589 0.8193934224276005 1.0 17.46489042619949 -7.024027404265046 24.972856678169368 0.966391298462563 0.9071256384666804 0.1590325179789258 0.06672466093090865 1528.4995850822597 1588639.9136399254 0.02575719709677377 0.020066580887735257 9.461774550675682e-08 7.024027404265046 -0.059265659995882625 DILS(ph)PDMISPPLGDFR ddPTM_PC-9_Lapatinib_30min_R1 1 DILSPDMISPPLGDFR 16 0 C9JEZ4;Q9UKI2 C9JEZ4 CDC42EP3 Cdc42 effector protein 3 1 DILS(1)PDMISPPLGDFR 72.815 0.015615 3020700.0 6031.0 18617.0 24089.0 25657.0 24306.0 18083.0 15973.0 15155.0 21303.0 17873.0 True False 5944.996834050057 18573.893480325063 22108.495406229056 27543.901369242987 22876.36886743459 17309.63224353186 16800.00378351075 15859.156626047547 18903.631809464976 20962.324235724478 0.28360389655258056 0.8860607856008164 1.0546776758920295 1.3139717265846902 1.091308798117346 0.8257496663481804 0.801438027319499 0.7565552582675925 0.9017908318224068 1.0 14.355511066723126 -4.765681174147385 4.117926041289857 0.9656926926944618 0.21584628653055196 0.6336991803605486 0.1551465616427267 0.17427977087701083 5.7596210728518455 0.04547553477422479 0.3969625885792314 1.7152160260833803e-05 4.765681174147385 -0.7498464061639099 DINAYNCEEPTEK ddPTM_PC-9_AZD4547_30min_R2 1 DINAYNCEEPTEK 13 0 P30041 P30041 PRDX6 Peroxiredoxin-6 0 133.88 0.0003795 0.0 4411.3 5307.6 6200.2 8108.3 5283.9 8216.2 8663.9 7307.6 6647.9 5732.3 False True 5814.001639259957 7023.17790422502 6117.98129686129 6239.05670698622 4550.321691753059 7702.439715158642 9434.970315801738 6178.378331942472 6999.294422043162 5531.61392177633 1.0510497879058316 1.2696435440978342 1.1060029465860957 1.1278908461823225 0.8226029068731254 1.3924398600626142 1.7056451244109874 1.116921466196334 1.26532591048862 1.0 12.433484751964691 -6.80634416707967 24.999767704416918 1.3289729205818122 1.0908379839025626 0.21907669117166995 0.20254823311942774 194.96604705301672 108541.73971835672 0.07233316127248131 0.06379211985305594 1.561909379506555e-07 6.80634416707967 -0.23813493667924956 DINAYNCEEPTEK ddPTM_PC-9_Lapatinib_30min_R1 2 DINAYNCEEPTEK 13 0 P30041 P30041 PRDX6 Peroxiredoxin-6 0 ; 197.38 3.8983e-06 12679300.0 31455.0 36630.0 33251.0 28661.0 36856.0 33272.0 41181.0 35491.0 35759.0 29698.0 False True 31006.445931859475 36545.18548554048 30517.231132571804 30768.8255502932 34688.20254168395 31849.034120820197 43313.15067981948 37140.041426265496 31731.444861036405 34831.259729902406 0.8901901961714191 1.0492065394398205 0.8761449160672464 0.8833681523117112 0.9958928505793996 0.9143807708303473 1.2435137579200282 1.0662847601340417 0.9110048016378567 1.0 15.088095030861048 DINAYNCEEPTEKLPFPIIDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DINAYNCEEPTEKLPFPIIDDR 22 1 P30041 P30041 PRDX6 Peroxiredoxin-6 0 64.76100000000001 0.0040449 2826800.0 4765.8 4368.6 4867.8 6188.1 7119.4 6012.5 5454.0 6312.7 6208.3 4987.4 False True 5572.5558111593755 4802.2857369284075 4983.866813234304 5841.400819090889 5724.404677040524 5697.193915598673 4937.357636459443 6146.998313858529 6299.084642550316 5891.576139763323 0.9458514460246349 0.8151105278122274 0.8459309860390798 0.9914835488021971 0.9716253412063152 0.9670067534470566 0.8380368036214138 1.0433537932865393 1.0691679939493004 1.0 12.524437926329519 -6.663449429165239 0.4242785022831396 1.0298928625900503 0.8550100425976691 0.32973285419180065 0.06823091549851262 1.7366984406031376 0.636104548111278 0.07223350608368716 0.12453016265590534 2.1704539244318803e-07 6.663449429165239 -0.1748828199923812 DINTFLGT(ph)PVQK ddPTM_PC-9_AZD4547_30min_R2 2 DINTFLGTPVQK 12 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 DINT(0.007)FLGT(0.993)PVQK;DINTFLGT(1)PVQK 161.04 0.001021 15909000.0 85109.0 116167.0 120043.0 79077.0 96201.0 133416.0 107197.0 146969.0 113596.0 98449.0 True False 112171.89162282656 153715.71098050114 118451.15138529713 60847.01937747124 82845.15170013368 125073.47642920147 116737.3253318942 124258.31806164204 119600.45264916957 95002.33047554357 1.1807277891114782 1.6180204234050042 1.2468236388768377 0.6404792290135985 0.8720328363045841 1.3165306135453079 1.2287838071714028 1.3079502096385924 1.2589212501472087 1.0 16.535675283774836 DINTFLGT(ph)PVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DINTFLGTPVQK 12 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 DINTFLGT(1)PVQK 98.0 0.0092801 5928300.0 52141.0 77023.0 62456.0 43599.0 47153.0 22859.0 45952.0 27780.0 23896.0 23388.0 True False 60967.44146830772 84669.33441272652 63945.187905699 41156.28937986515 37913.70814064271 21660.23379903035 41599.09389633008 27050.80443534303 24245.433793209486 27628.059260693884 2.2067218291747834 3.064613899000303 2.314501619615138 1.4896554619172153 1.3722899528662187 0.7839940400680301 1.5056828097771102 0.9791062115545659 0.8775655779667152 1.0 14.753846602817845 -5.817442639719038 1.9975263516238673 1.0883343263362713 2.669634928542653 0.8428144866038473 0.28072093853893343 0.11329492484045828 0.9232857991865318 0.08420812923450925 0.15748070668787048 1.5225002067515104e-06 5.817442639719038 1.5813006022063816 up DINTFLGT(ph)PVQK ddPTM_PC-9_Lapatinib_30min_R1 2 DINTFLGTPVQK 12 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 DINT(0.001)FLGT(0.999)PVQK;DINT(0.002)FLGT(0.998)PVQK 122.12 0.0010163 10862000.0 53890.0 122815.0 118843.0 89919.0 101356.0 102424.0 116097.0 93854.0 80216.0 73227.0 True False 53121.518717784325 122530.62941323123 109072.18728724624 96531.9432209909 95394.4393535631 98043.5642820056 122107.9345930163 98214.79947087195 71181.22936807228 85884.18938115562 0.6185250055982952 1.4266959995330226 1.2699914626099789 1.1239780443473752 1.110733419514514 1.141578735136993 1.421774315771894 1.1435725268942443 0.8288048112344482 1.0 16.390104946293455 -8.183920508909043 6.452863177440056 0.9162361159816701 1.1767401495015686 0.16422412754457283 0.21597661686618871 0.3564344502753474 23.990135370326886 0.14433604085762808 0.053125447722295036 6.547560063665088e-09 8.183920508909043 0.2605040335198985 DINTFVGT(ph)PVEK ddPTM_PC-9_AZD4547_30min_R2 2 DINTFVGTPVEK 12 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 DINT(0.005)FVGT(0.995)PVEK;DINTFVGT(1)PVEK 151.49 0.00017871 19288800.0 89463.0 127557.0 108664.0 93595.0 88669.0 124121.0 103999.0 143550.0 109498.0 108036.0 True False 117910.37305400081 168787.30573691163 107223.0443602038 72018.1187783353 76358.8398883499 116359.69424858272 113254.70952724098 121367.64595083782 115285.8407354025 104253.692523599 1.1309946938072286 1.6190055397673777 1.0284819824097131 0.6907968152977716 0.7324329531164109 1.1161206038073268 1.086337632612912 1.1641568083870495 1.1058202155219226 1.0 16.669738957302364 -5.391411119310369 7.367739190192674 0.9815126411913602 1.372340423246004 0.408479359931766 0.18553957960732217 0.249147198739218 13.654261155480645 0.05225511188400026 0.10944238107481503 4.0605875684591236e-06 5.391411119310369 0.39082778205464375 DINTFVGT(ph)PVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DINTFVGTPVEK 12 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 DINT(0.002)FVGT(0.998)PVEK;DINT(0.001)FVGT(0.999)PVEK;DINTFVGT(1)PVEK 171.15 0.0026698 22458200.0 118628.0 185176.0 151457.0 113899.0 132721.0 85387.0 120677.0 87101.0 70859.0 65846.0 True False 138709.37739019975 203559.0494944506 155068.30928387112 107517.60829554035 106715.27279567016 80909.15540477734 109245.60093417944 84814.69104113804 71895.17882294225 77783.35856335088 1.7832783252374929 2.617000001724808 1.9935923589308024 1.3822700675488617 1.371955065539573 1.0401859330730834 1.4044855217353986 1.090396359936817 0.9243002635889914 1.0 16.247173908974197 -5.794539234289277 2.3002985851405753 1.1556144126012176 2.231145316816669 0.781328747030233 0.23642371137707135 0.12589607545417836 1.3593529158021556 0.0690331801455544 0.12573322391349592 1.604947260147098e-06 5.794539234289277 1.0755309042154515 DINTFVGT(ph)PVEK ddPTM_PC-9_Lapatinib_30min_R1 1 DINTFVGTPVEK 12 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 DINT(0.001)FVGT(0.999)PVEK 87.824 0.020462 8937200.0 27642.0 77896.0 71494.0 65363.0 70205.0 70876.0 72072.0 67020.0 56562.0 56356.0 True False 27247.820011078038 77715.63659791605 65616.039294821 70170.01306457611 66075.67992834063 67844.79870002571 75803.53550899557 70133.99386853889 50191.39193573478 66097.0595103502 0.41223951886711807 1.1757805441518392 0.9927225171725851 1.0616207980263952 0.9996765426152396 1.0264420112274713 1.146851858018365 1.061075854025799 0.7593589231889395 1.0 16.01229847088609 -4.753080530757308 24.99990018374382 1.029968026343414 0.4122383717378837 0.7486127211030562 0.10646005840497808 151.22056732790927 452240.43839582877 0.025783570327480722 0.2876034091417999 1.7657103765578345e-05 4.753080530757308 -0.6177296546055302 DINVSVGSQQPDTKDS(ph)PVCPHFTTNGNENSSIEK ddPTM_PC-9_Lapatinib_30min_R1 1 DINVSVGSQQPDTKDSPVCPHFTTNGNENSSIEK 34 1 E9PEM5;A0A494C1L5;P50851-2;P50851;A0A494C0R9;A0A494BZW2 E9PEM5 LRBA Lipopolysaccharide-responsive and beige-like anchor protein 1 DINVS(0.005)VGS(0.046)QQPDT(0.214)KDS(0.688)PVCPHFT(0.036)T(0.005)NGNENS(0.004)S(0.002)IEK 59.461000000000006 0.00021977 10474000.0 7940.7 5696.4 9444.8 7457.5 8778.9 11191.0 7099.9 9857.1 13367.0 6115.5 True False 7827.46416185397 5683.210335785772 8668.285001982316 8005.949427490722 8262.542361981468 10712.387017495153 7467.49808192249 10315.096851112721 11861.4676992498 7172.556026608463 1.0913074966324354 0.7923549589159603 1.2085350006085778 1.1161919680781258 1.1519662350951902 1.4935243416370352 1.0411209134121593 1.4381340226337982 1.653729528949875 1.0 12.808271616947696 -5.973138457112559 0.8486984885162113 1.3440332897852574 0.9406842679930092 0.2780550436716548 0.20836109260929322 0.8761285282213027 1.2549840154023084 0.09703253133486528 0.23694586684877722 1.0638038136249043e-06 5.973138457112559 -0.4033490217922482 DIPGLTDTTVPR ddPTM_PC-9_Lapatinib_30min_R1 2 DIPGLTDTTVPR 12 0 P62753;A2A3R5 P62753 RPS6 40S ribosomal protein S6 0 ; 164.97 0.00090038 17534700.0 83815.0 86632.0 89485.0 94397.0 98459.0 95795.0 86902.0 83288.0 93530.0 93425.0 False True 82619.78273021127 86431.40892665439 82127.88872208938 101339.27027916057 92667.83519784194 91698.07115905189 91401.36034524834 87157.8645377928 82995.66648543671 109573.38676901258 0.7540132249848117 0.7887992830673118 0.749524050901338 0.9248529525950491 0.8457148029310385 0.8368644418407643 0.8341565688567062 0.7954291375653737 0.7574436542734293 1.0 16.741537912893463 -11.963156511479749 2.2551379709972004 2.841608855373456 0.8128157522386606 0.5549849723932756 0.0510658271634629 4073764.311344443 244525.44355834989 38740048.3786134 0.013688666225107355 1.0885377343209151e-12 11.963156511479749 -2.028793103134795 DIQDSLTVS(ph)NEVQTAK ddPTM_PC-9_Lapatinib_30min_R1 1 DIQDSLTVSNEVQTAK 16 0 P47755 P47755 CAPZA2 F-actin-capping protein subunit alpha-2 1 DIQDS(0.001)LT(0.011)VS(0.953)NEVQT(0.036)AK 73.435 0.014536000000000002 3802400.0 5841.2 17558.0 15491.0 14275.0 18887.0 17933.0 21627.0 23400.0 16700.0 17767.0 True False 5757.90341685511 17517.345529760314 14217.389776989261 15324.831120004026 17776.103793270686 17166.047393864777 22746.74023827629 24487.24942589988 14819.070141203834 20838.002276960615 0.2763174387029074 0.8406441892526444 0.6822818036020954 0.735427077716937 0.8530618029984911 0.8237856568834476 1.0915988939796812 1.1751246160949906 0.7111559901108385 1.0 14.346929353745997 -4.623805411040607 0.4631238248621595 0.9962400473489194 1.6556314179955492e-12 0.5607128225520762 0.15787124027782926 4.515667561126114 0.6741438929538415 0.10912274021897676 2.549988272339882 2.3779054866852988e-05 4.623805411040607 -0.9962400473472637 DIQDSLTVSNEVQT(ph)AK ddPTM_PC-9_AZD4547_30min_R2 1 DIQDSLTVSNEVQTAK 16 0 P47755 P47755 CAPZA2 F-actin-capping protein subunit alpha-2 1 DIQDSLT(0.001)VS(0.075)NEVQT(0.924)AK 86.463 0.010952 4495400.0 26038.0 39930.0 30622.0 21069.0 25011.0 37562.0 33273.0 42063.0 36983.0 28981.0 True False 34317.54237595512 52836.591626291585 30215.93227194065 16211.867562805108 21538.654371285567 35213.2422020872 36234.23254165808 35563.12986158194 38937.84587770908 27966.384011129863 1.2270997338196339 1.889289355580044 1.0804375803434412 0.579691230598608 0.7701622906527267 1.2591274648904658 1.2956352357615426 1.2716384730835697 1.3923089185292197 1.0 14.77140610828474 -6.943150434190564 24.999918030101533 1.2646639254082428 1.1109375483041106 0.03741831685849084 0.33255886303383825 348.15665819505915 153101.84333912193 0.1328315759658061 0.11714642606879552 1.1398548876579e-07 6.943150434190564 -0.15372637710413217 DIS(ph)LDSELHDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DISLDSELHDLR 12 0 H0YJ97;Q15643-2;Q15643 H0YJ97 TRIP11 Thyroid receptor-interacting protein 11 1 DIS(0.999)LDS(0.001)ELHDLR 100.18 0.0033728 0.0 3338.7 3346.7 2619.6 2934.4 4837.7 2672.7 3208.9 3492.9 2033.4 1187.6 True False 3903.8759676691866 3678.9382584302275 2682.061198888322 2769.9950814531594 3889.7874127200257 2532.538906980551 2904.9297615758537 3401.2150760334634 2063.134628185142 1402.902478963572 2.782713714037535 2.6223763330635297 1.9117944683295158 1.9744744363838889 2.7726712804682614 1.805213794227183 2.070656945251063 2.424413048686173 1.4706187059483509 1.0 10.45419900993809 -10.22279522342867 0.16773822912760522 7.9119634300535e-11 2.7683459106762394 0.5990254912907647 0.3490812774440462 15.217830069052942 0.6231843274331526 9.2430284770541 1.8711336204775604 5.986938219230621e-11 10.22279522342867 2.7683459105971195 DIS(ph)SSLNSLADSNAR ddPTM_PC-9_AZD4547_30min_R2 1 DISSSLNSLADSNAR 15 0 O94776 O94776 MTA2 Metastasis-associated protein MTA2 1 DIS(0.743)S(0.023)S(0.235)LNSLADSNAR 249.54 1.6618e-40 6033700.0 17622.0 16226.0 22372.0 27765.0 26484.0 23570.0 19710.0 24453.0 16072.0 21657.0 True False 23225.429439629796 21470.737183275905 22075.33266239487 21364.20821497386 22807.153747116332 22096.164173984216 21464.151816670583 20674.35072403928 16921.533108361687 20898.795021877766 1.1113286395371795 1.027367231498247 1.0562969127782464 1.0222698577888762 1.091314294591665 1.0572936932896366 1.0270521240196373 0.989260419196249 0.8096894146599118 1.0 14.351132141660537 -7.940863478658726 3.125656582179824 0.9025515046725187 1.0555695657980502 0.5795731871797327 0.05097825334812545 0.1591213711458863 3.075531418785768 0.032272202593579484 0.012781319245492013 1.1458730923398798e-08 7.940863478658726 0.1530180611255315 DIS(ph)SSLNSLADSNAR ddPTM_PC-9_Lapatinib_30min_R1 2 DISSSLNSLADSNAR 15 0 O94776 O94776 MTA2 Metastasis-associated protein MTA2 1 DIS(0.649)S(0.019)S(0.332)LNSLADSNAR;DIS(0.688)S(0.153)S(0.153)LNS(0.005)LADSNAR 180.56 2.0901999999999997e-05 9904700.0 28446.0 32485.0 30854.0 24973.5 32552.0 35668.0 28096.0 28003.8 33528.0 22322.7 True False 28040.354823642483 32409.782978372463 28317.303219884216 26810.134499153814 30637.35535969437 34142.56278616902 29550.67340521619 29304.95878089808 29751.72357450792 26181.148951871943 1.07101315053775 1.2379052973553772 1.0815913110589266 1.0240243676256575 1.1702066787066583 1.3040895511855617 1.1287004042312407 1.119315230770374 1.136379600039695 1.0 14.676240790461174 -9.183216531496312 1.2672775181234823 0.9999281773115866 1.1458471353069473 0.2322503711621754 0.07718928940105067 6.498204221226632 11.012933305268342 0.07900720587411852 0.023282343424098847 6.558182054955416e-10 9.183216531496312 0.1459189579953607 DISENKR ddPTM_PC-9_Lapatinib_30min_R1 4 DISENKR 7 1 P11142;E9PKE3;P11142-2;E9PN89;E9PNE6;A8K7Q2 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 ;;; 85.359 0.012236 15592900.0 83777.0 110700.0 53449.0 113452.0 101802.0 46209.9 200703.0 218567.0 97682.0 121461.0 False True 82582.32461717974 110443.68095138775 49054.62953910647 121795.6385447774 95814.20651043269 44233.610297538165 211094.4192926788 228722.4207380623 86680.0245229385 142455.37201339085 0.5797066368926893 0.7752861783338435 0.34435085771630514 0.854973995177441 0.6725910378544807 0.31050854504370806 1.4818284232400576 1.6055724505535833 0.6084714342312801 1.0 17.120150501370226 -7.263386031712645 24.999360646985295 1.2244324516591463 0.6027024453748008 0.4753540459625194 0.2987073157210282 146.82505478462505 1885541.2182131421 0.11843307635273029 0.08439420741730687 5.4527296836356875e-08 7.263386031712645 -0.6217300062843455 DISGPS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 2 DISGPSPSK 9 0 S4R3D6;Q96GX9-3;Q96GX9 S4R3D6 APIP Methylthioribulose-1-phosphate dehydratase 1 DIS(0.007)GPS(0.978)PS(0.015)K;DIS(0.007)GPS(0.948)PS(0.045)K 131.12 0.0012439999999999999 269670000.0 1203670.0 1202850.0 1328580.0 1124010.0 1264590.0 1503940.0 1382800.0 1396650.0 1389130.0 1294240.0 True False 1586412.0221086817 1591647.7394862203 1310962.161121249 864886.8602813879 1089023.5069123206 1409898.3940526878 1505866.521161449 1180829.8343241885 1462556.5758348966 1248929.0515359947 1.270217888003833 1.274410053580492 1.0496690420556418 0.6925027960697265 0.8719658699371158 1.128885898137068 1.205726233455343 0.945473910525138 1.1710485667990285 1.0 20.2522600927837 -5.3024616871889325 4.870490690166329 0.9995437273512116 1.2746290258807778 0.35661871079371577 0.14251872102077703 0.2158638691786079 12.522992917735895 0.04126605964988308 0.09390734676321774 4.9835441811440285e-06 5.3024616871889325 0.2750852985295662 DISGPS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DISGPSPSK 9 0 S4R3D6;Q96GX9-3;Q96GX9 S4R3D6 APIP Methylthioribulose-1-phosphate dehydratase 1 DIS(0.02)GPS(0.965)PS(0.015)K;DIS(0.001)GPS(0.944)PS(0.054)K;DIS(0.007)GPS(0.939)PS(0.054)K 105.36 0.0026414999999999998 264837000.0 722265.0 746198.0 618856.0 631294.0 706899.0 571988.0 734019.0 611215.0 516274.0 543040.0 True False 844530.1991159967 820275.605989218 633611.8740644505 595924.643862762 568387.2154669317 541991.9423526739 664487.4064826405 595171.2538858228 523823.5305555507 641488.8532977239 1.3165157816452946 1.2787059381817765 0.9877207854933411 0.9289711595131726 0.8860437910105591 0.8448968981556533 1.035851836032204 0.9277967198123637 0.8165746417302701 1.0 19.29106467126882 -5.292948900976806 2.767781216652544 0.9180372821210034 1.3193613523739045 0.8554202493138072 0.061333490589998825 0.09349545998700588 1.398235957973107 0.016915761935027685 0.049693791133788724 5.093908023762981e-06 5.292948900976806 0.40132407025290107 DISGPS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 3 DISGPSPSK 9 0 S4R3D6;Q96GX9-3;Q96GX9 S4R3D6 APIP Methylthioribulose-1-phosphate dehydratase 1 DIS(0.002)GPS(0.713)PS(0.285)K;DIS(0.012)GPS(0.938)PS(0.05)K;DISGPS(0.961)PS(0.039)K 125.23 0.0014334 292611000.0 1197635.0 1220747.0 1147315.0 1183111.0 1204691.0 1073136.0 1226652.0 1130114.0 1187008.0 1042221.0 True False 1180556.505280638 1217920.4353239704 1052987.1894639744 1270120.9296825957 1133833.4438936326 1027240.4748821994 1290162.0385056667 1182623.22212399 1053314.6592916208 1222367.5111778094 0.9657950612112682 0.9963619158614956 0.8614325723115555 1.039066334852743 0.9275716456183705 0.8403695823790377 1.0554616567504596 0.9674858103717728 0.8617004703247568 1.0 20.221246673499657 DISGPS(ph)PSKK ddPTM_PC-9_AZD4547_30min_R2 3 DISGPSPSKK 10 1 S4R3D6;Q96GX9-3;Q96GX9 S4R3D6 APIP Methylthioribulose-1-phosphate dehydratase 1 DIS(0.275)GPS(0.653)PS(0.071)KK;DIS(0.004)GPS(0.802)PS(0.194)KK;DISGPS(0.872)PS(0.128)KK 118.76 0.0012436 148970000.0 239223.0 226492.0 232718.0 253766.0 249771.0 242066.0 233725.0 254529.0 253703.0 238955.0 True False 315290.9378524887 299701.1097075393 229632.0072647598 195264.169345617 215094.60801128918 226929.57475348632 254526.07221467927 215197.39154455406 267113.2226350599 230589.2581822412 1.3673270833947755 1.2997184347185724 0.9958486751506661 0.8468051412494428 0.9328041111147243 0.9841289943096025 1.1038071513874255 0.9332498540520803 1.1583940411654075 1.0 17.814965782187265 -5.22967840359964 4.310837893358472 0.9869251447498445 1.3473223074025746 0.7272903865287061 0.08333148024865174 0.10362318024731165 4.579782288295942 0.022373721657475504 0.061190729443696454 5.892798573790429e-06 5.22967840359964 0.36039716265273014 DISGPS(ph)PSKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DISGPSPSKK 10 1 S4R3D6;Q96GX9-3;Q96GX9 S4R3D6 APIP Methylthioribulose-1-phosphate dehydratase 1 DIS(0.195)GPS(0.797)PS(0.008)KK 105.66 0.0035674 8627300.0 40447.0 51803.0 41130.0 47617.0 45810.0 46733.0 45268.0 48685.0 37609.0 37589.0 True False 47293.87823533579 56945.659485899894 42110.69518639361 44949.17386639692 36833.85934983654 44282.23921125535 40979.88732806123 47407.07033602145 38158.960475762244 44403.588145639726 1.0650913633424437 1.2824562577943772 0.9483624397261403 1.0122869737231082 0.82952438953863 0.9972671367461035 0.922895852327315 1.0676405289710051 0.8593665978209762 1.0 15.438388641502321 -5.279306493229616 24.56582198711944 0.9550587930263097 1.1737738028021099 0.5254501897785278 0.08328859774060242 400.4947627213104 550647.2742030192 0.020239920240663723 0.042283397269239284 5.256461728999634e-06 5.279306493229616 0.21871500977580016 DISGPSPS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DISGPSPSK 9 0 S4R3D6;Q96GX9-3;Q96GX9 S4R3D6 APIP Methylthioribulose-1-phosphate dehydratase 1 DIS(0.034)GPS(0.397)PS(0.569)K;DIS(0.01)GPS(0.218)PS(0.772)K 115.23 0.0019913 26861000.0 242726.0 259740.0 220039.0 242500.0 264730.0 173675.0 252682.0 184052.0 178349.0 168234.0 True False 283814.7177429753 285525.27063814155 225285.5642625546 228913.51119560743 212858.05688020564 164567.1772626359 228746.13170074165 179220.8300192134 180957.01672184104 198733.49246038878 1.4281171946874769 1.436724465027212 1.1336064267448938 1.1518617640216537 1.0710728938788823 0.8280797324358256 1.151019533088188 0.901814927118716 0.9105511833034841 1.0 17.600475504219453 -5.379632857136052 0.8136952298957264 0.9599905308433145 1.5629103836977287 0.7811497580881648 0.09207690770489534 0.5465891156580438 0.48964664727439877 0.037866670464888535 0.25545108351279955 4.172219445475371e-06 5.379632857136052 0.6029198528544142 DISGPSPS(ph)KK ddPTM_PC-9_Lapatinib_30min_R1 1 DISGPSPSKK 10 1 S4R3D6;Q96GX9-3;Q96GX9 S4R3D6 APIP Methylthioribulose-1-phosphate dehydratase 1 DIS(0.003)GPS(0.418)PS(0.579)KK 73.95100000000001 0.039101 60329000.0 53224.0 88337.0 112130.0 121500.0 128980.0 108630.0 91955.0 94650.0 124540.0 95899.0 True False 52465.01599991376 88132.46110390898 102911.10423431719 130435.51531211815 121393.6499844365 103984.14812889828 96715.97996072935 99047.78453681275 110512.99373566029 112475.01437261478 0.46645929580505885 0.783573681635086 0.9149685804296621 1.1596843622531368 1.0792943718351125 0.9245088672263923 0.8598885761447619 0.880620332340484 0.982555942331738 1.0 16.779245025708505 -4.830994405580865 1.9272929975863382 0.9762318224446322 0.34524966222006326 0.7726684996353994 0.085351796326198 0.3713985338810956 1.616956942652203 0.026769854359884417 0.410320167417429 1.4757255428981317e-05 4.830994405580865 -0.630982160224569 down DISLSDYK ddPTM_PC-9_AZD4547_30min_R2 1 DISLSDYK 8 0 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 93.429 0.033319999999999995 3958700.0 34687.0 34834.0 42273.0 52667.0 51373.0 46206.0 36564.0 48348.0 42767.0 41541.0 False True 45716.744465579315 46093.40928400303 41712.4323993125 40525.436847038625 44240.745712528595 43316.73151561797 39818.12516614628 40876.92752651416 45027.576309439035 40086.662234096315 1.140447767853674 1.1498440307858204 1.0405563864539802 1.0109456509594132 1.103627572038137 1.080577157126698 0.9933010868706942 1.0197139209995307 1.1232558112842868 1.0 15.290834677836722 -5.260713686218809 24.88959197105061 1.0472892177715816 1.1451459088292628 0.4725373696161219 0.04168301479226345 49.89783442246129 1711301.3082067673 0.010889541808477649 0.02551675184415983 5.4863854217798735e-06 5.260713686218809 0.09785669105768124 DISLSDYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DISLSDYK 8 0 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 93.551 0.032897 12217000.0 115830.0 113600.0 110880.0 134920.0 134470.0 133820.0 131110.0 116780.0 111270.0 98183.0 False True 135437.73125321875 124877.45724375505 113523.79971474179 127360.86981654199 108121.56880097179 126802.24362335382 118690.3116458009 113714.64873863789 112897.1132478414 115982.80068379991 1.1677397894749773 1.0766894445341457 0.9787985722489836 1.0981013483521729 0.9322207099976837 1.0932848911714987 1.023344072966322 0.980444066432353 0.9733953015639712 1.0 16.823551355583547 -4.888790607662158 2.6892107630798887 1.0130194103900316 1.1809297469748257 0.4939345369074922 0.04955423070577082 0.29982517448883594 3.4525247176626417 0.01240240702221596 0.10247441709557645 1.29184197692442e-05 4.888790607662158 0.16791033658479404 DISLSDYK ddPTM_PC-9_Lapatinib_30min_R1 2 DISLSDYK 8 0 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 ; 95.741 0.029182 69823000.0 167283.0 203343.0 173337.0 179566.0 185005.0 173515.0 166153.0 185392.0 214510.0 152274.0 False True 164897.5137440549 202872.17177685638 159085.90096016956 192771.8826546164 174123.3696338245 166094.1679332207 174755.5893471274 194005.98912677 190349.62490955906 178594.35800764913 0.9233075198097377 1.1359383019712608 0.890766666623119 1.0793839447400688 0.974965679634554 0.9300079229048599 0.9785056554790083 1.0862940536926748 1.0658210429100254 1.0 17.4463269792915 -7.752159254702273 24.98144127235443 1.0570431637947701 0.9903726705090529 0.13678656927647326 0.07193062515203515 347.55133502534454 935589.0965633754 0.03272999554993133 0.018564681945854995 1.76945998277771e-08 7.752159254702273 -0.06667049328571728 DISS(ph)SLNSLADSNAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DISSSLNSLADSNAR 15 0 O94776 O94776 MTA2 Metastasis-associated protein MTA2 1 DIS(0.047)S(0.691)S(0.251)LNS(0.011)LADSNAR 225.37 2.7036999999999998e-24 4943000.0 15748.0 12804.0 15579.0 17907.0 19268.0 15710.0 16520.0 17208.0 14431.0 11144.0 True False 18413.82536282215 14075.096501311937 15950.462443686503 16903.7288452773 15492.573716495323 14886.139944125596 14955.106005557385 16756.30823338312 14642.026074230243 13164.318984144542 1.3987677892795103 1.069185312074583 1.211643569477287 1.2840564609256735 1.1768610085455231 1.13079453346997 1.1360333963017544 1.272857962008127 1.1122509331371788 1.0 13.684345269440051 -14.522878737048869 0.13653998980324217 0.33454738157315506 1.2691992398895786 0.36929020092114284 0.08769736051081964 165.7315499467657 1.3957502293817674 30.049091171298027 0.5677008853144153 3.000000056860974e-15 14.522878737048869 0.9346518583164236 DISSS(ph)LNSLADSNAR ddPTM_PC-9_AZD4547_30min_R2 2 DISSSLNSLADSNAR 15 0 O94776 O94776 MTA2 Metastasis-associated protein MTA2 1 DIS(0.038)S(0.058)S(0.863)LNS(0.041)LADSNAR;DIS(0.385)S(0.132)S(0.483)LNSLADSNAR 224.67 2.9598000000000003e-24 12676600.0 26958.0 30530.0 41747.0 44403.0 44334.0 39239.0 36092.0 42077.0 36827.0 38245.0 True False 35530.08323876632 40398.22545331035 41193.407502994785 34166.57436951138 38178.989360544314 36785.37912698204 39304.118080531465 35574.96648326997 38773.60003618941 36906.05419087202 0.9627169313471062 1.0946232627410504 1.116169376708474 0.9257715331150682 1.034491229083686 0.9967302095405306 1.0649775204159473 0.9639330799028831 1.0506026961229384 1.0 15.1715698797024 -5.7428459756847134 24.99997873722363 1.0070687536665557 1.0615151529547757 0.16802774524048614 0.05335891735969665 423.62808270142284 569589.6331516214 0.014002820248876835 0.024199060422799127 1.807815161376472e-06 5.7428459756847134 0.05444639928822004 DISSS(ph)LNSLADSNAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DISSSLNSLADSNAR 15 0 O94776 O94776 MTA2 Metastasis-associated protein MTA2 1 DIS(0.001)S(0.017)S(0.982)LNSLADSNAR;DIS(0.016)S(0.007)S(0.977)LNSLADSNAR;DIS(0.213)S(0.116)S(0.671)LNSLADSNAR 195.17 1.2464000000000002e-09 12025000.0 39861.0 40458.0 52441.0 56774.0 55378.0 44040.0 43679.0 46900.0 42745.0 36611.2 True False 46608.68000936335 44474.4028623929 53691.392323599975 53593.13684379143 44527.078434299256 41730.46487201088 39541.40891142502 45668.92469465758 43370.06475940488 43248.52074590026 1.077694200992565 1.028345064648456 1.2414619366765196 1.2391900559713775 1.0295630386045098 0.9648992416917916 0.9142834998622084 1.0559650112191816 1.0028103623293552 1.0 15.400363167812092 -6.457297175527127 6.621563999112731 0.9874985784814196 1.1446346776753615 0.5462139520009562 0.06877487455008485 0.20823398221814443 17.32183111218331 0.023653926171332676 0.026653499235587914 3.4890149027802296e-07 6.457297175527127 0.1571360991939419 DISSS(ph)LNSLADSNAR ddPTM_PC-9_Lapatinib_30min_R1 1 DISSSLNSLADSNAR 15 0 O94776 O94776 MTA2 Metastasis-associated protein MTA2 1 DIS(0.096)S(0.323)S(0.579)LNS(0.002)LADSNAR 212.72 1.9891e-14 7037000.0 26533.0 23947.0 27992.0 22113.0 20466.0 26511.0 20760.0 21111.0 24103.0 19016.0 True False 26154.63455444372 23891.552192799285 25690.605812244747 23739.263786805535 19262.230117704134 25377.18633015943 21834.85122053987 22091.894129494543 21388.26632415784 22302.890262772733 1.1727015757280659 1.07123121314363 1.1518958085502793 1.0644030216312526 0.8636651972348188 1.1378429446213172 0.9790144220449266 0.9905395161437719 0.9589907887346084 1.0 14.444943062680428 -6.004308227884879 21.342722092692505 0.9920738134287587 1.122918219363791 0.48023122650028793 0.06712470108604163 24.633085637755805 122043.15078488944 0.01842280970065223 0.026443419179771444 9.90128980204309e-07 6.004308227884879 0.13084440593503233 DISTNYYASQK ddPTM_PC-9_Lapatinib_30min_R1 2 DISTNYYASQK 11 0 P14625;H0YIV0 P14625 HSP90B1 Endoplasmin 0 ; 178.67 0.009407200000000001 13989200.0 40658.0 46367.0 45282.0 40538.0 40248.0 38327.0 43607.0 37422.0 41178.0 33291.0 False True 40078.20946423594 46259.64006028 41559.08875357483 43519.299750803715 37880.691770612524 36687.84355460077 45864.75708931028 39160.762735727556 36540.10001643663 39045.30499253086 1.0264539993195767 1.1847683113021963 1.0643812043861571 1.1145847051042042 0.9701727718059542 0.9396224094451033 1.174654855381049 1.0029570198828972 0.935838509224772 1.0 15.2528614613043 -6.25118407920629 24.587856898166052 1.0093485487868268 1.1014081615153206 0.2806407832708473 0.07305223125488847 798.8137523118676 1915213.5816145726 0.022025981279686527 0.028099010275617613 5.608102217296561e-07 6.25118407920629 0.09205961272849383 DISTTLNADEAVAR ddPTM_PC-9_Lapatinib_30min_R1 1 DISTTLNADEAVAR 14 0 Q92598-2;Q92598-3;Q92598;A0A0A0MSM0;Q92598-4;D6RJ96;E9PDE8;O95757 Q92598-2 HSPH1;HSPA4L Heat shock protein 105 kDa;Heat shock 70 kDa protein 4L 0 128.21 0.00080204 0.0 11389.0 10494.0 13269.0 10227.0 13369.0 12338.0 7563.9 10005.0 11243.0 9682.0 False True 11226.590771513187 10469.70178774944 12178.07403982122 10979.127696271895 12582.661704465281 11810.332501282757 7955.521731553057 10469.868825048206 9976.694945961352 11355.52079954594 0.9886460488859384 0.9219922161710169 1.0724364170340976 0.9668537348556399 1.1080655767869676 1.0400520336993264 0.7005862498064523 0.9220069259585921 0.878576607984398 1.0 13.47110625359885 -7.182952381869803 24.99999915495265 0.868783443397932 1.0165223356340316 0.3956393145250038 0.08525087004410833 108.03113464566741 34409.85919889268 0.031782714574034227 0.024618782712238534 6.562172131614941e-08 7.182952381869803 0.1477388922360996 DITAEEEEEEVES(ph)LKS(ph)IR ddPTM_PC-9_Lapatinib_30min_R1 1 DITAEEEEEEVESLKSIR 18 1 V9GYZ0;Q9BZ23-3;Q9BZ23-4;Q9BZ23;A0A2R8YF29 V9GYZ0 PANK2 Pantothenate kinase 2, mitochondrial 2 DIT(0.001)AEEEEEEVES(1)LKS(1)IR 51.695 0.012398000000000001 347640.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DITDPLSLNTCTDEGHVVLAS(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 6 DITDPLSLNTCTDEGHVVLASPLK 24 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 DITDPLSLNTCTDEGHVVLAS(1)PLK;DITDPLSLNTCTDEGHVVLAS(1)PLK;DITDPLSLNT(0.001)CT(0.036)DEGHVVLAS(0.963)PLK;DITDPLSLNTCT(0.005)DEGHVVLAS(0.995)PLK;DITDPLSLNTCTDEGHVVLAS(1)PLK;DITDPLSLNTCTDEGHVVLAS(1)PLK 137.3 5.535800000000001e-09 331369500.0 267946.0 250837.0 302163.0 372831.0 359622.0 344142.0 321752.0 357343.0 340369.0 352436.0 True False 353147.2543769751 331915.15486511623 298156.1211902029 286880.5731315294 309694.69282757345 322622.7463370085 350387.3046837844 302123.85027523746 358360.21046291455 340097.3229131697 1.0383711678528478 0.9759416864032698 0.876678824273854 0.8435249377272308 0.9106060882068209 0.948618894066912 1.0302559916746001 0.8883452762501537 1.0536990041359648 1.0 18.375588124307633 -7.010762114328918 16.169883914834003 0.9845806209737554 0.9245361418690501 0.17663738057693856 0.06403961028614787 10.063545665882694 15119.238114846294 0.02470057102426571 0.020377277500357015 9.755238365323737e-08 7.010762114328918 -0.06004447910470534 DITDPLSLNTCTDEGHVVLAS(ph)PLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DITDPLSLNTCTDEGHVVLASPLK 24 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 DITDPLS(0.011)LNT(0.042)CT(0.055)DEGHVVLAS(0.892)PLK;DITDPLSLNT(0.001)CT(0.004)DEGHVVLAS(0.994)PLK;DITDPLSLNTCTDEGHVVLAS(1)PLK;DITDPLS(0.003)LNT(0.009)CT(0.026)DEGHVVLAS(0.962)PLK;DITDPLSLNTCTDEGHVVLAS(1)PLK;DITDPLSLNTCTDEGHVVLAS(1)PLK 125.42 4.5123999999999994e-09 330435900.0 270606.0 254994.0 265481.0 328660.0 331704.0 297618.0 336871.0 332452.0 294237.0 249871.0 True False 316414.2510878752 280308.1191233628 271811.0738822987 310246.24573009607 266708.9823570874 282010.38815345464 304960.1401451642 323725.48726201017 298539.6594832851 295170.6343222529 1.0719706308671262 0.9496477173855178 0.9208608251508809 1.0510742250578504 0.9035755977876431 0.9554147850818028 1.0331655818180872 1.0967401550812215 1.0114138222752678 1.0 18.171189673392675 -7.337343448047637 5.73499383187163 1.0445457320044795 0.9720384043699591 0.21510963638367597 0.05494069065888796 0.3084596537857552 17.814132958707713 0.022946714652802947 0.015352192746028866 4.5989273811793644e-08 7.337343448047637 -0.07250732763452039 DITDPLSLNTCTDEGHVVLAS(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 6 DITDPLSLNTCTDEGHVVLASPLK 24 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 DITDPLSLNTCTDEGHVVLAS(1)PLK;DITDPLSLNT(0.002)CT(0.01)DEGHVVLAS(0.988)PLK;DITDPLSLNTCTDEGHVVLAS(1)PLK;DITDPLSLNTCTDEGHVVLAS(1)PLK;DIT(0.001)DPLS(0.32)LNT(0.009)CT(0.001)DEGHVVLAS(0.67)PLK;DITDPLSLNTCT(0.001)DEGHVVLAS(0.999)PLK 130.26 1.9248000000000001e-07 361873200.0 271719.4 366210.4 359086.9 358042.7 373778.2 334295.5 313106.0 315413.1 350555.8 295466.2 True False 267844.6315287645 365362.4623186999 329564.1611975184 384374.3545534343 351793.3011522151 319998.4607458722 329317.0966405758 330068.34409813234 311072.51428777404 346537.1389860366 0.7729175358014284 1.0543241148344042 0.9510211868252249 1.109186610353248 1.0151676734607955 0.9234175063665145 0.9503082342174163 0.9524761041887408 0.897659959904928 1.0 18.402650451214114 -6.766040279238455 24.94574665780522 0.9421481094835357 0.9901324041265244 0.035431258365649754 0.08572243742017849 345.8445842929965 1875131.216355636 0.029260269497495744 0.026647599704676943 1.7137983515543314e-07 6.766040279238455 0.0479842946429887 DITDPLSLNTCTDEGHVVLASPLKT(ph)GR ddPTM_PC-9_Lapatinib_30min_R1 1 DITDPLSLNTCTDEGHVVLASPLKTGR 27 1 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 DITDPLS(0.013)LNT(0.046)CT(0.046)DEGHVVLAS(0.071)PLKT(0.824)GR 47.383 0.018272 2753400.0 52238.0 9845.0 11393.0 10324.0 7303.9 7439.5 6791.7 7168.4 14457.0 5227.9 True False 51493.07654072404 9822.204507375 10456.311518251798 11083.2613998544 6874.298962019895 7121.3299273215325 7143.340993956681 7501.470033530796 12828.700421040941 6131.535549261127 8.398071922934403 1.6019159358145794 1.7053332618306065 1.8075833224501119 1.1211382380141748 1.1614268351065304 1.1650166482060893 1.2234243727796297 2.092249211959123 1.0 12.582032704725492 -4.761191972211 6.52592166624186 1.419539645224068 8.592563207489363 0.9750266556059771 0.33463174051189837 0.016912404038397465 3.4245985582143943 0.08585625428481523 0.5391002524083005 1.733037769657567e-05 4.761191972211 7.1730235622652945 DITSDTSGDFR ddPTM_PC-9_AZD4547_30min_R2 3 DITSDTSGDFR 11 0 P04083;Q5T3N1 P04083;Q5T3N1 ANXA1 Annexin A1;Annexin 0 ;; 177.06 0.00067691 134328900.0 365455.0 428687.0 570920.0 709687.0 596306.0 515879.0 438979.0 581424.0 482421.0 502124.0 False True 481662.0880637796 567251.6893188092 563349.2277674983 546079.6267048499 513519.20489080006 483621.00457831094 478047.2805849948 491578.280594356 507920.78917800914 484544.7915946507 0.9940506975188319 1.1706898911284707 1.1626360194967735 1.1269951430242109 1.059797182425166 0.9980934951064079 0.9865904842599331 1.014515663199181 1.048243212988478 1.0 18.886270509787387 -6.485771638408621 3.158649228888757 1.0093586354968147 1.120758577487934 0.510963505014689 0.04768932791308324 0.20248646335431403 4.081271259043747 0.016247407101644254 0.01771466075567131 3.267596043950066e-07 6.485771638408621 0.11139994199111936 DITSDTSGDFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DITSDTSGDFR 11 0 P04083;Q5T3N1 P04083;Q5T3N1 ANXA1 Annexin A1;Annexin 0 125.97 0.0020012 32682000.0 130190.0 158610.0 170930.0 172600.0 195230.0 162520.0 168240.0 120830.0 152410.0 112930.0 False True 152228.59563029028 174355.7525830274 175005.61945563514 162929.78157675033 156976.08297028166 153997.16509989105 152303.08924787954 117658.34052996765 154638.70791860783 133403.31504661168 1.141115538074155 1.3069821579929013 1.3118536026971102 1.2213323298586845 1.1767030145797617 1.1543728508252122 1.1416739471179123 0.88197463825286 1.1591818978754496 1.0 17.025434992097864 -7.080990496706557 1.117048129647417 1.0169992010201248 1.2526970035243554 0.5479794986356702 0.0826790750497797 0.35571180889600995 0.8972526778232446 0.050455562728332654 0.03361638135696152 8.298689266252836e-08 7.080990496706557 0.23569780250423067 DITSDTSGDFR ddPTM_PC-9_Lapatinib_30min_R1 3 DITSDTSGDFR 11 0 P04083;Q5T3N1 P04083;Q5T3N1 ANXA1 Annexin A1;Annexin 0 ;; 192.64 0.0010215 130322000.0 609614.0 582409.0 682954.0 654375.0 633764.0 581663.0 576675.0 504076.0 655597.0 549906.0 False True 600920.7925704828 581060.467743602 626804.158398678 702499.9204310087 596487.2475479646 556786.6294126785 606532.4098075547 527497.2111799094 581756.7621175335 644956.5193963142 0.931722952630901 0.9009296755190265 0.9718549073437897 1.0892205897671299 0.9248487760171533 0.863293280504919 0.9404237209281567 0.8178802683840644 0.9020092744578561 1.0 19.298842377041304 -6.514270822153498 24.813096687892866 0.8954036391488002 0.9730023935163861 0.2006262988004548 0.0636067950901383 554.4398451972289 1598226.4363273694 0.020894885296780467 0.021917553207084876 3.060054615909995e-07 6.514270822153498 0.0775987543675859 DITTS(ph)ADQIAEVK ddPTM_PC-9_AZD4547_30min_R2 2 DITTSADQIAEVK 13 0 F5H527;Q76I76;A0A3B3IS79 F5H527 SSH2 Protein phosphatase Slingshot homolog 2 1 DITT(0.006)S(0.994)ADQIAEVK;DIT(0.015)T(0.019)S(0.966)ADQIAEVK 220.52 6.512e-15 30242000.0 90485.0 101029.0 105926.0 152116.0 135086.0 142705.0 120459.0 153784.0 119442.0 118292.0 True False 119257.34779508038 133684.6485202257 104521.35202918119 117048.00636877218 116331.6406540915 133781.63379076897 131179.61763999582 130020.21640476212 125755.46027432401 114150.63308528281 1.0447366306412187 1.1711248979263116 0.9156440853997935 1.0253820167718626 1.0191063992363427 1.1719745232671612 1.1491799396503612 1.1390231739461578 1.1016623988442635 1.0 16.80057933528252 -6.748091872042016 24.998906728868462 1.1233577044841898 1.0355629359173504 0.2149041719891982 0.07223559516758205 330.60230937659225 619192.8075400689 0.02392453449154751 0.023793055159855806 1.7861096955340027e-07 6.748091872042016 -0.08779476856683943 DITTS(ph)ADQIAEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DITTSADQIAEVK 13 0 F5H527;Q76I76;A0A3B3IS79 F5H527 SSH2 Protein phosphatase Slingshot homolog 2 1 DIT(0.04)T(0.066)S(0.894)ADQIAEVK;DIT(0.001)T(0.023)S(0.977)ADQIAEVK 230.86 4.7182e-20 14796200.0 85560.0 74400.0 79544.0 116991.0 126427.0 107432.0 103219.0 91827.0 92681.0 76094.0 True False 100043.61811297055 81785.94030752934 81440.63063229978 110436.37355993927 101654.53691381322 101798.07679677285 93441.34907915427 89416.63854874873 94036.2842897741 89889.2398402275 1.1129654482649072 0.9098523967150989 0.9060108949308662 1.228582795407248 1.1308866010492225 1.1324834538339912 1.0395165121569658 0.994742404181871 1.0461350486100196 1.0 16.455860808323308 -5.730708244801893 24.999940342725022 1.0839447430028495 0.9696338924145531 0.24358072153271781 0.0848838472580878 286.73308924563696 233256.79881570197 0.024099245422084806 0.04173524764819123 1.859052931030751e-06 5.730708244801893 -0.11431085058829638 DITTS(ph)ADQIAEVK ddPTM_PC-9_Lapatinib_30min_R1 2 DITTSADQIAEVK 13 0 F5H527;Q76I76;A0A3B3IS79 F5H527 SSH2 Protein phosphatase Slingshot homolog 2 1 DITT(0.02)S(0.98)ADQIAEVK;DITT(0.025)S(0.975)ADQIAEVK 246.66 3.9902e-34 25699000.0 171595.0 145316.0 141670.0 129059.0 150256.0 141667.0 121593.0 130317.0 134066.0 101364.0 True False 169148.02383333087 144979.52973018875 130022.43946201487 138550.42938820348 141418.23749466197 135608.23265190647 127888.49058088157 136372.00356559816 118966.07530243306 118884.6323409597 1.4227913272105377 1.219497649741551 1.0936858440131445 1.1654191686511888 1.1895417827350145 1.1406708334091802 1.07573609862458 1.1470953047529717 1.0006850587823646 1.0 16.859202711148754 -1.5228787456123662 0.7917883600854453 1.1009890195505505 76.66381528282034 0.7295308609629503 0.06029671759707682 255.90798713104823 0.922542646212022 0.02171007540692392 34656.761555582634 0.029999999977064273 1.5228787456123662 75.56282626326978 DIVEAHYR ddPTM_PC-9_AZD4547_30min_R2 2 DIVEAHYR 8 0 A0A2R8YDT1;P15104 A0A2R8YDT1 GLUL Glutamine synthetase 0 ; 123.98 0.00028660000000000003 2358400.0 31617.0 30046.0 47365.0 62821.0 58386.0 50401.0 43132.0 58646.0 44051.0 44495.0 False True 41670.548325546224 39757.78191844618 46736.90915225876 48338.589024774825 50280.11171572025 47249.41750245983 46970.664442244335 49583.608251012425 46379.4459281011 42937.24359322396 0.9704989151218445 0.9259509598497015 1.0884934672339899 1.1257962779986945 1.1710139614936783 1.100429686406707 1.0939375821892978 1.1547925321139465 1.0801682187028039 1.0 15.389941958216403 -5.326474635990949 4.852112832560651 1.1117600855856038 0.9480290395650179 0.6424189691560657 0.04553673997050252 0.10610852585875177 4.960099551625079 0.011392908044415137 0.025277538812039417 4.715474102162344e-06 5.326474635990949 -0.16373104602058586 DIVEAHYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DIVEAHYR 8 0 A0A2R8YDT1;P15104 A0A2R8YDT1 GLUL Glutamine synthetase 0 114.89 0.0017059999999999998 0.0 13987.0 13969.0 14983.0 19920.0 20013.0 16395.0 15011.0 12099.0 13502.0 13935.0 False True 16354.722844157583 15355.750002095161 15340.251543343917 18803.946981511355 16091.596314522578 15535.21733825201 13589.049409771293 11781.414069950151 13699.441206725565 16461.30519060069 0.9935252797266667 0.932839153657342 0.9318976451577552 1.1423120319917461 0.9775407313212797 0.9437415295065745 0.8255146996199645 0.7157035200755083 0.8322208383906196 1.0 14.006791108829969 -7.132875501823051 2.939482207406785 0.8187581145332193 0.9951924687447319 0.40129773727681417 0.08576902432816084 0.24566834132464554 4.0688138380040275 0.03631324923705546 0.0270387679809942 7.364181745036286e-08 7.132875501823051 0.17643435421151255 DIVEAHYR ddPTM_PC-9_Lapatinib_30min_R1 2 DIVEAHYR 8 0 A0A2R8YDT1;P15104 A0A2R8YDT1 GLUL Glutamine synthetase 0 ; 114.89 0.0030698 3167700.0 46046.0 41946.0 46972.0 33011.0 38890.0 49032.0 39923.0 42271.0 43696.0 31090.0 False True 45389.37559619779 41848.876614154564 43110.14347716349 35438.7390614678 36602.566660681776 46935.0156591746 41990.01759526076 44235.06497787234 38774.4963407211 36463.86507517902 1.2447768634130443 1.1476807663661834 1.1822702664207858 0.9718865235049089 1.0038038092017068 1.287165130805711 1.1515514745540072 1.213120575305748 1.0633677000717878 1.0 15.15417987096642 DIVQFVPFR ddPTM_PC-9_Lapatinib_30min_R1 1 DIVQFVPFR 9 0 O75131;E7ENV7;Q86YQ8-2;Q9HCH3-2;Q96FN4-2;Q96FN4;Q8IYJ1;Q96A23;O95741;Q9UBL6-2;Q86YQ8;Q96A23-2;Q9HCH3;O95741-2;Q9UBL6 O75131 CPNE3;CPNE8;CPNE5;CPNE2;CPNE9;CPNE4;CPNE6;CPNE7 Copine-3;Copine-8;Copine-5;Copine-2;Copine-9;Copine-4;Copine-6;Copine-7 0 96.948 0.022765999999999998 2238200.0 5976.4 9878.7 10363.0 6389.6 10852.0 5521.8 6779.6 9419.4 9455.2 7658.5 False True 5891.175440062469 9855.826477095514 9510.994142336815 6859.512499080751 10213.70669585289 5285.6454859444875 7130.614515162432 9857.059711210304 8390.25580832997 8982.261520690208 0.6558677262393695 1.0972544558397783 1.0588640867813408 0.7636732111707272 1.1370974528325752 0.5884537511816214 0.7938551442459568 1.0973917524562204 0.9340916860418079 1.0 13.132863011801872 -7.7621091679891405 24.999987729790664 1.011806276407067 0.8819438665984595 0.11294001715684032 0.17755592786152413 45.18813670998673 1686402.4496469144 0.09062656270679433 0.04764342875256463 1.729381592371219e-08 7.7621091679891405 -0.12986240980860753 DIVVLGVEK ddPTM_PC-9_Lapatinib_30min_R1 2 DIVVLGVEK 9 0 O14818;O14818-4 O14818 PSMA7 Proteasome subunit alpha type-7 0 ; 129.38 0.0059886 8035200.0 103602.0 104538.0 110205.0 103117.0 99844.0 90257.0 106494.0 88416.0 93222.0 109523.0 False True 102124.61648172002 104295.94868379539 101144.37030360215 110700.56816822808 93971.37222085662 86396.91850934319 112007.7382408562 92524.13013847686 82722.35668882048 128453.9046197758 0.7950292891758285 0.8119328796778262 0.7873981768245192 0.8617921619113278 0.7315571488388177 0.672590831435436 0.8719683420476759 0.7202905229883727 0.6439847580630504 1.0 16.97089121901552 -6.277440550339758 24.22121352899631 0.7593012271694091 0.8119849052686232 0.027582062853665268 0.0985447602305308 1678.5261227338372 2540803.218834133 0.029275466457701207 0.033301273947479774 5.279094662547348e-07 6.277440550339758 0.05268367809921415 DIYLS(ph)PDR ddPTM_PC-9_AZD4547_30min_R2 1 DIYLSPDR 8 0 Q15696 Q15696 ZRSR2 U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 1 DIYLS(1)PDR 102.95 0.0041206 19726000.0 41982.0 49755.0 65571.0 51196.0 59602.0 57282.0 53997.0 76599.0 56887.0 51739.0 True False 55331.40272015316 65837.33073794493 64701.485696669646 39393.5531703152 51327.2911054081 53700.14748469089 58802.62839395037 64762.38461991108 59893.93068288775 49927.63335812594 1.1082320350188946 1.3186551476554138 1.2959053202576685 0.7890130278707418 1.028033729082301 1.0755596424830531 1.1777571745122581 1.2971250640978103 1.1996148556306396 1.0 15.607550902011239 -14.522142216212886 0.00972913173286882 0.2941504704110401 1.8417436765899056 0.02097625116438806 0.1549280428022267 117046.54416962646 86.1965343260987 7937.959169822882 5911.67477094395 3.0050920792150042e-15 14.522142216212886 1.5475932061788655 DIYLS(ph)PDR ddPTM_PC-9_Lapatinib_30min_R1 1 DIYLSPDR 8 0 Q15696 Q15696 ZRSR2 U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 1 DIYLS(1)PDR 100.82 0.0047757 16563000.0 21591.0 30282.0 28825.0 25518.0 30153.0 27944.0 30909.0 32756.0 29268.0 23749.0 True False 21283.108380695525 30211.88388952052 26455.119767717726 27394.678845552575 28379.459823078894 26748.900260645572 32509.31678110148 34277.96334165711 25971.529634296643 27853.983006446655 0.7640956905793209 1.0846521979469916 0.949778699929372 0.9835102878899662 1.0188654102542756 0.9603258627125134 1.1671335038000623 1.2306305828406536 0.9324170847769122 1.0 14.765596021397796 -7.244947462430483 23.997298992017363 1.101764506371606 0.9691132156720613 0.22288944656600662 0.1088251725892415 659.4644462950274 959583.6902070628 0.040038127652823316 0.030910080181962115 5.689217504107816e-08 7.244947462430483 -0.13265129069954462 DKAIT(ph)PPLPESTVPFSNGVLK ddPTM_PC-9_AZD4547_30min_R2 2 DKAITPPLPESTVPFSNGVLK 21 1 Q92667-2;Q92667;I3NI36 Q92667-2 AKAP1 A-kinase anchor protein 1, mitochondrial 1 DKAIT(0.998)PPLPES(0.001)T(0.001)VPFSNGVLK;DKAIT(0.987)PPLPES(0.006)T(0.006)VPFSNGVLK 83.236 0.00039668 32306000.0 176377.0 160014.0 195417.0 184844.0 206260.0 160310.0 224457.0 199233.0 191097.0 179397.0 True False 232461.2171304946 211735.39625568286 192825.64289680024 142231.07161133172 177624.3593067597 150285.7903577181 244433.238169175 168446.11776888368 201197.9972877425 173116.3656341972 1.342803242656421 1.2230813388440087 1.1138498788973519 0.8215922919261861 1.026040251342199 0.8681200636760066 1.411959159803953 0.9730224935799429 1.1622124606802517 1.0 17.4013825914189 -5.164605048403896 2.5503217005961236 1.0415567091062152 1.3247003735908993 0.2879577060288333 0.1551417392040096 0.40195970276108206 4.827656021830207 0.04219790768537435 0.1665501370569356 6.8453388603052184e-06 5.164605048403896 0.2831436644846841 DKAIT(ph)PPLPESTVPFSNGVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DKAITPPLPESTVPFSNGVLK 21 1 Q92667-2;Q92667;I3NI36 Q92667-2 AKAP1 A-kinase anchor protein 1, mitochondrial 1 DKAIT(0.997)PPLPES(0.002)T(0.001)VPFSNGVLK;DKAIT(0.981)PPLPES(0.008)T(0.011)VPFSNGVLK 83.31700000000001 0.00039 35228000.0 168863.0 126668.0 124625.0 141003.0 201027.0 133369.0 146156.0 144126.0 128479.0 128138.0 True False 197448.17070372397 139242.7619203518 127596.53264294428 133103.05904789397 161637.2024343937 126374.89485729374 132311.0456021937 140342.84521411985 130357.76231661187 151368.40506015005 1.304421293368738 0.9198931696810849 0.8429535383704452 0.8793318460018266 1.0678397672893698 0.8348829123691663 0.8740994895838177 0.9271607582728448 0.8611953218692562 1.0 17.207704579233173 -4.76198449668246 6.450281827955421 0.9070174068247527 1.3158013198016205 0.7420582211354854 0.06940819901796921 0.058884042818098635 11.329738707219587 0.016998574742495054 0.10601602473150924 1.7298781107963334e-05 4.76198449668246 0.4087839129768678 DKAIT(ph)PPLPESTVPFSNGVLK ddPTM_PC-9_Lapatinib_30min_R1 1 DKAITPPLPESTVPFSNGVLK 21 1 Q92667-2;Q92667;I3NI36 Q92667-2 AKAP1 A-kinase anchor protein 1, mitochondrial 1 DKAIT(1)PPLPESTVPFSNGVLK 102.43 0.00010096 13068000.0 127690.0 120490.0 60684.0 51322.0 46609.0 53524.0 46359.0 40439.0 82225.0 29132.0 True False 125869.11718452169 120211.0128078835 55694.79576701411 55096.39108517314 43867.5502568197 51234.903290538015 48759.242183670896 42317.94356982755 72963.95463236434 34167.427384050025 3.683892140011679 3.5182927721388872 1.630055290408357 1.6125413969824705 1.2838997143021036 1.4995247583215878 1.4270679977045213 1.2385463820311602 2.135482833174184 1.0 15.060334004548201 -5.264011227586497 4.03808188084067 1.468946344092032 3.664840980615544 0.9033098794263221 0.27852468968203364 0.051907763746179426 2.0363465268960708 0.06961355434474166 0.18045787292162785 5.444885762840852e-06 5.264011227586497 2.195894636523512 DKAPVQPQQS(ph)PAAAPGGTDEKPSGK ddPTM_PC-9_AZD4547_30min_R2 5 DKAPVQPQQSPAAAPGGTDEKPSGK 25 2 Q13200;C9JPC0;F8WBS8 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 1 DKAPVQPQQS(1)PAAAPGGTDEKPSGK;DKAPVQPQQS(1)PAAAPGGTDEKPSGK;DKAPVQPQQS(1)PAAAPGGTDEKPSGK;DKAPVQPQQS(1)PAAAPGGTDEKPSGK;DKAPVQPQQS(1)PAAAPGGTDEKPSGK 105.65 8.0124e-07 238547100.0 748571.0 725468.0 847571.0 835833.0 848855.0 876860.0 811443.0 887746.0 779732.0 838151.0 True False 986601.0067559374 959961.3437000372 836331.6547469464 643144.6153411216 731006.1355538617 822029.8055833608 883659.8550266179 750565.2540736499 820947.0416655722 808807.5886033105 1.2198216493735543 1.1868846895437104 1.034030425198119 0.7951762871707669 0.9038072167648671 1.016347790458894 1.0925464442693547 0.9279898762692912 1.0150090741399012 1.0 19.62543700776701 -5.324480471480171 3.6132726994808397 0.9637495656455602 1.2089240825099472 0.6032075737221079 0.07616044751068765 0.16015974802095714 4.134510033285452 0.022131588000821437 0.054060756648706576 4.737176089189828e-06 5.324480471480171 0.24517451686438696 DKAPVQPQQS(ph)PAAAPGGTDEKPSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DKAPVQPQQSPAAAPGGTDEKPSGK 25 2 Q13200;C9JPC0;F8WBS8 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 1 DKAPVQPQQS(0.992)PAAAPGGT(0.006)DEKPS(0.001)GK;DKAPVQPQQS(1)PAAAPGGTDEKPSGK;DKAPVQPQQS(1)PAAAPGGTDEKPSGK;DKAPVQPQQS(1)PAAAPGGTDEKPSGK;DKAPVQPQQS(1)PAAAPGGTDEKPSGK;DKAPVQPQQS(1)PAAAPGGTDEKPSGK 133.48 1.1119000000000002e-07 193716200.0 480863.0 470607.0 433066.0 492019.0 507038.0 446312.0 514430.0 447050.0 415377.0 369157.0 True False 562263.6084228313 517325.75282668683 443391.93585195014 464452.7705771211 407687.54370273754 422906.613032628 465699.466249328 435315.41118862946 421451.1028089201 436082.2418547948 1.289352224092748 1.1863031858998383 1.0167621913840492 1.0650577482854096 0.9348868276972581 0.9697863669794792 1.067916602768693 0.9982415457623228 0.96644867036171 1.0 18.734240716611303 -5.020762856100839 1.4857086559088726 0.9966956968836734 1.3428193070889922 0.861116133072314 0.03897272266496101 0.25647186585731674 0.7294996046014519 0.011651358954050006 0.11534205722066553 9.533165747296512e-06 5.020762856100839 0.3461236102053188 DKAPVQPQQS(ph)PAAAPGGTDEKPSGK ddPTM_PC-9_Lapatinib_30min_R1 5 DKAPVQPQQSPAAAPGGTDEKPSGK 25 2 Q13200;C9JPC0;F8WBS8 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 1 DKAPVQPQQS(1)PAAAPGGTDEKPSGK;DKAPVQPQQS(1)PAAAPGGTDEKPSGK;DKAPVQPQQS(1)PAAAPGGTDEKPSGK;DKAPVQPQQS(1)PAAAPGGTDEKPSGK;DKAPVQPQQS(1)PAAAPGGTDEKPSGK 113.79 2.8954e-08 188351200.0 324945.0 392458.0 419516.0 378584.0 426803.0 415271.0 382527.0 409634.0 410812.0 339414.0 True False 320311.2247123848 391549.2876135477 385025.013858591 406426.3302792027 401699.2866669835 397510.82737398177 402332.3763410138 428667.0910824383 364542.0265178584 398081.2576592732 0.80463779328829 0.9835913650290052 0.9672020635247858 1.020963239186388 1.0090886695570256 0.9985670506352256 1.0106790224356135 1.076833141060221 0.9157477763745365 1.0 18.602703422935797 -4.108548072190262 1.4498671947597248 1.0057836223891632 1.5221777632200815e-20 0.6883198063975744 0.03893102770829694 3.8262813734172476 1.794991551775289 0.010355479727795831 9.000048595035128 7.788465990116856e-05 4.108548072190262 -1.0057836223891632 DKDDDEVFEK ddPTM_PC-9_Lapatinib_30min_R1 2 DKDDDEVFEK 10 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73;C9JF13;C9J6B6 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 0 ; 105.13 0.0032461999999999994 10977800.0 87254.0 108029.0 82408.0 82634.0 107136.0 90686.0 97851.0 117142.0 85000.0 97351.0 False True 86009.74195957629 107778.86548778192 75632.73234407912 88711.18001894323 100834.47111748015 86807.57117939115 102917.24599137976 122584.84496789602 75426.40491031895 114177.99063794661 0.7532952846605034 0.9439548277701257 0.6624107844383703 0.7769551690591795 0.8831340484631738 0.7602828767118012 0.901375522693562 1.073629377106549 0.6606037160830125 1.0 16.80092505282861 -7.3381317399445205 6.65734391115601 0.9162845523499761 0.8004388013473056 0.16851762340277954 0.12171166079962294 0.45685732644820526 33.19578116208356 0.049165939833828 0.03298340420138077 4.590587397194903e-08 7.3381317399445205 -0.11584575100267047 DKDDQEWESPS(ph)PPKPTVFISGVIAR ddPTM_PC-9_AZD4547_30min_R2 7 DKDDQEWESPSPPKPTVFISGVIAR 25 2 P51397 P51397 DAP Death-associated protein 1 1 DKDDQEWES(0.018)PS(0.976)PPKPT(0.005)VFIS(0.001)GVIAR;DKDDQEWES(0.002)PS(0.997)PPKPT(0.001)VFISGVIAR;DKDDQEWES(0.057)PS(0.942)PPKPTVFISGVIAR;DKDDQEWES(0.001)PS(0.999)PPKPTVFISGVIAR;DKDDQEWES(0.126)PS(0.851)PPKPT(0.022)VFIS(0.001)GVIAR;DKDDQEWES(0.06)PS(0.931)PPKPT(0.007)VFIS(0.001)GVIAR;DKDDQEWESPS(0.999)PPKPT(0.001)VFISGVIAR 133.65 4.9325e-07 721449800.0 443024.9 490514.3 415202.0 336701.6 391522.0 491580.0 477038.4 420308.6 489434.8 429983.1 True False 583897.6027096263 649063.4549450604 409696.1501918321 259080.24810786368 337165.9284616561 460841.4248895706 519493.89345416735 355359.5636007829 515305.3243270529 414929.5225456689 1.4072211568058768 1.56427397829621 0.9873873222572135 0.6243957926116193 0.8125860179653671 1.1106498811225187 1.252005136359006 0.8564335490533107 1.2419104843771058 1.0 18.662506784128823 -5.267867095334508 24.213753520232952 0.975434791479501 1.4857475860137765 0.53807805742299 0.1851410525366359 232.29802733372026 875091.7594213978 0.051708585086547014 0.11209267188858626 5.3967575114195975e-06 5.267867095334508 0.5103127945342756 DKDDQEWESPS(ph)PPKPTVFISGVIAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 DKDDQEWESPSPPKPTVFISGVIAR 25 2 P51397 P51397 DAP Death-associated protein 1 1 DKDDQEWES(0.01)PS(0.99)PPKPTVFISGVIAR;DKDDQEWES(0.002)PS(0.996)PPKPT(0.001)VFISGVIAR;DKDDQEWES(0.002)PS(0.982)PPKPT(0.014)VFIS(0.002)GVIAR;DKDDQEWES(0.008)PS(0.989)PPKPT(0.002)VFIS(0.001)GVIAR;DKDDQEWES(0.003)PS(0.983)PPKPT(0.01)VFIS(0.004)GVIAR 113.04 1.7447e-07 646270000.0 345048.0 416339.0 274735.0 376294.0 375869.0 330087.0 447424.0 337511.0 314006.0 328886.0 True False 403457.81139135576 457670.38443140447 281285.7243382895 355211.4671416077 302220.1676481935 312776.6566350469 405040.75965075765 328651.6938724647 318597.74370901135 388510.42833985714 1.0384735697195318 1.1780131266670872 0.724010744165223 0.9142906888225906 0.7778946087486239 0.8050663092148439 1.0425479732462684 0.8459275991041614 0.8200494001420001 1.0 18.567593798197926 -5.251280670138351 24.998810861352478 0.863396039769467 1.1082433638088456 0.4953630565200363 0.09767660202276574 544.6466639109589 1340274.0392656296 0.02421878771463894 0.0625453374789456 5.606855064480268e-06 5.251280670138351 0.2448473240393786 DKDDQEWESPS(ph)PPKPTVFISGVIAR ddPTM_PC-9_Lapatinib_30min_R1 11 DKDDQEWESPSPPKPTVFISGVIAR 25 2 P51397 P51397 DAP Death-associated protein 1 1 DKDDQEWES(0.009)PS(0.801)PPKPT(0.09)VFIS(0.1)GVIAR;DKDDQEWESPS(0.987)PPKPT(0.012)VFIS(0.001)GVIAR;DKDDQEWES(0.017)PS(0.976)PPKPT(0.006)VFIS(0.001)GVIAR;DKDDQEWES(0.009)PS(0.989)PPKPT(0.001)VFIS(0.001)GVIAR;DKDDQEWES(0.209)PS(0.789)PPKPT(0.001)VFIS(0.001)GVIAR;DKDDQEWES(0.044)PS(0.954)PPKPT(0.001)VFISGVIAR;DKDDQEWESPS(0.997)PPKPT(0.002)VFIS(0.001)GVIAR;DKDDQEWES(0.069)PS(0.666)PPKPT(0.063)VFIS(0.202)GVIAR;DKDDQEWES(0.244)PS(0.752)PPKPT(0.003)VFISGVIAR;DKDDQEWES(0.014)PS(0.981)PPKPT(0.004)VFIS(0.001)GVIAR;DKDDQEWES(0.016)PS(0.878)PPKPT(0.07)VFIS(0.035)GVIAR 117.4 1.967e-08 440466400.0 603139.2 664097.2 516874.3 585110.3 668891.6 596943.4 596092.0 631854.6 574698.2 594992.2 True False 594538.3244058181 662559.5237354103 474378.89024649735 628141.2633327415 629548.7111794834 571413.5223250312 626954.727059444 661212.8714146235 509969.63687566447 697835.8089927293 0.8519745142686029 0.9494490182321863 0.6797858237329862 0.9001275876619367 0.9021444630194417 0.8188366302810132 0.8984272789961917 0.9475192629753865 0.7307874292260313 1.0 19.41252810483055 -11.733498432626757 2.342826007765861 1.4458635520694343 0.856866062295955 0.2130768375312495 0.0843575937505966 12860559.216098398 2409731.910493479 30430534.7752081 0.02160217855978849 1.8471474612717244e-12 11.733498432626757 -0.5889974897734793 DKDQPPS(ph)PSPPPQSEALSSTSR ddPTM_PC-9_Lapatinib_30min_R1 1 DKDQPPSPSPPPQSEALSSTSR 22 1 H3BU99;H3BPL8;H3BR21;H3BUX9;Q7L1V2 H3BU99 MON1B Vacuolar fusion protein MON1 homolog B 1 DKDQPPS(0.964)PS(0.036)PPPQSEALSSTSR 79.373 0.00027375 9043400.0 17144.0 35951.0 30842.0 25910.0 35723.0 34662.0 36678.0 37986.0 33398.0 29501.0 True False 16899.523416175452 35867.75766832284 28306.289813562867 27815.507833226242 33621.84337412023 33179.58706106847 38577.00737316768 39750.96823471078 29636.36554346861 34600.20854238841 0.488422588420876 1.0366341469988993 0.8180959308058817 0.8039115659996589 0.9717237204778811 0.9589418231517435 1.1149356896478624 1.1488649898168162 0.8565371941952709 1.0 15.078493112849683 -4.025352737358411 0.5199168646573814 1.023328696703535 5.944832484600421e-17 0.47257606208260716 0.13167218814211382 8.733483661278463 1.0017825057203653 0.0749034623911017 6.435102546853196 9.432944139998243e-05 4.025352737358411 -1.023328696703535 DKDQPPSPS(ph)PPPQSEALSSTSR ddPTM_PC-9_AZD4547_30min_R2 2 DKDQPPSPSPPPQSEALSSTSR 22 1 H3BU99;H3BPL8;H3BR21;H3BUX9;Q7L1V2 H3BU99 MON1B Vacuolar fusion protein MON1 homolog B 1 DKDQPPS(0.15)PS(0.847)PPPQS(0.001)EALS(0.001)ST(0.001)SR;DKDQPPS(0.016)PS(0.978)PPPQS(0.001)EALS(0.001)ST(0.002)S(0.002)R 89.87899999999999 9.725200000000001e-05 18066200.0 19773.0 25625.0 21665.4 21765.7 18722.7 26619.0 25043.0 32310.0 27800.0 23705.7 True False 26060.402696050383 33907.7801258132 21378.102640079116 16747.954141712806 16123.376282326502 24954.509721989234 27271.77848528064 27317.23190993777 29269.451245175154 22875.770658453508 1.1392141967649962 1.4822573906721226 0.9345303797307941 0.7321263354038641 0.7048233051054948 1.0908707774077788 1.192168731382286 1.194155699399048 1.2794957460529937 1.0 14.481532726504636 -9.432577770363247 14.67071172514326 0.9999355734621792 1.0758782442605745 0.01105757043485378 0.22675531219028508 0.0 0.0 0.2462764666743969 0.059730816776614494 3.693365002856964e-10 9.432577770363247 0.07594267079839534 DKDQPPSPS(ph)PPPQSEALSSTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DKDQPPSPSPPPQSEALSSTSR 22 1 H3BU99;H3BPL8;H3BR21;H3BUX9;Q7L1V2 H3BU99 MON1B Vacuolar fusion protein MON1 homolog B 1 DKDQPPS(0.002)PS(0.997)PPPQSEALSSTSR 110.44 7.8884e-06 5537000.0 8112.6 12119.0 9189.0 10818.0 14541.0 7459.9 10360.0 7505.6 5820.8 7702.3 True False 9485.902948846267 13322.09422831923 9408.100609476562 10211.902532429214 11691.795433441892 7068.689711596598 9378.62580009531 7308.585952840557 5905.918188128293 9098.666018626749 1.0425597477066164 1.4641810350051643 1.0340087865865546 1.1223516185255566 1.285001055045487 0.7768929749839819 1.0307693216670915 0.8032590643373932 0.6490971507293183 1.0 13.151439327843176 -6.763325044300841 24.99968905764283 0.8508802161428841 1.1924915813414003 0.5449171221973952 0.15425444622840376 39.05404961744432 517763.32774996466 0.05218198790659163 0.04836204708857493 1.7245466854046118e-07 6.763325044300841 0.3416113651985162 DKDSGSSS(ph)PLPK ddPTM_PC-9_AZD4547_30min_R2 1 DKDSGSSSPLPK 12 1 Q86VQ1;H7C0B2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 DKDS(0.236)GS(0.042)S(0.236)S(0.485)PLPK 118.24 0.0027794 0.0 25577.0 29523.0 24289.0 18806.0 24981.0 27748.0 34611.0 32358.0 36417.0 26716.0 True False 33709.95396535079 39065.732396268606 23966.911989849337 14470.567249803638 21512.81935344786 26012.913173513527 37691.311949608615 27357.814612868056 38341.928273220976 25780.68097171753 1.3075664681756078 1.5153103379668413 0.9296461957751243 0.5612949970436564 0.8344550470582336 1.0090079933129292 1.461998307607062 1.0611750187235436 1.487234891711497 1.0 14.654002751144464 -7.218645210264324 23.33623155453915 1.2577000135023901 1.014206637929072 0.13510347572982206 0.2795062509284978 478.702724129574 261042.56944295627 0.11769377206941743 0.0911639791360306 6.044422168647693e-08 7.218645210264324 -0.24349337557331818 DKDVTLS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 2 DKDVTLSPVK 10 1 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 DKDVT(0.004)LS(0.996)PVK;DKDVT(0.013)LS(0.987)PVK 63.754 0.025376 79563000.0 247550.0 280980.0 249670.0 205186.0 221900.0 281890.0 304670.0 302240.0 305670.0 265780.0 True False 326265.7506401294 371801.29013662395 246359.21266852017 157883.53779209877 191093.01527281085 264263.3737379889 331785.03977600357 255535.7527842643 321827.09216232697 256475.1230971364 1.2721146078427292 1.4496582968626137 0.9605579273870356 0.6155900653659208 0.7450742706162461 1.0303664953809293 1.2936343913960988 0.9963373823491009 1.2548082179511788 1.0 17.968459372296785 -7.021038103337693 24.177086073322094 1.139619893193932 0.9965116447050049 0.06038911266373437 0.23831197253798503 1709.6380826720551 1964719.4495283153 0.10282573505057158 0.08060277459759836 9.527125729974445e-08 7.021038103337693 -0.14310824848892723 DKDVTLS(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DKDVTLSPVK 10 1 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 DKDVT(0.004)LS(0.996)PVK;DKDVT(0.001)LS(0.999)PVK;DKDVT(0.008)LS(0.992)PVK;DKDVT(0.005)LS(0.995)PVK 76.311 0.010998 111630000.0 367679.0 513788.0 382308.0 425546.0 444058.0 281444.0 413784.0 316505.0 286202.0 266550.0 True False 429919.79270873126 564793.4771334003 391423.6726311644 401704.03725874703 357048.02259702544 266684.58118615404 374587.3839832661 308197.0791147676 290387.1628090109 314873.4049913611 1.3653734672209823 1.7937160400983883 1.2431144276599146 1.2757636271941362 1.1339415045447279 0.846958101124707 1.1896444032595999 0.9787967933437356 0.9222346447994806 1.0 18.264412383363357 -5.829446469827018 1.1969394597384617 0.9994744519003057 1.5798149056695614 0.6820783887125312 0.14663961220264266 0.2744156021870592 0.7828731787044843 0.0512359546193195 0.12365304038962642 1.4809947881452905e-06 5.829446469827018 0.5803404537692557 DKDVTLS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 2 DKDVTLSPVK 10 1 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 DKDVT(0.002)LS(0.998)PVK;DKDVT(0.022)LS(0.978)PVK 73.80199999999999 0.012742 99270000.0 206676.0 344240.0 308870.0 314710.0 392260.0 340970.0 367710.0 386320.0 301530.0 332970.0 True False 203728.76234026346 343442.93343004247 283475.90087267937 337854.8232417848 369188.03801283246 326387.5079398913 386748.2245811521 404269.83753049636 267568.5161483347 390523.4208453629 0.5216812909690627 0.87944260215327 0.7258870678205199 0.8651333190476341 0.9453672130948103 0.8357693559924343 0.9903329837272278 1.035199980209578 0.685153570480181 1.0 18.575049548090163 -4.180308498848103 0.7657655021982134 0.9141362496581519 1.7787783813787405e-23 0.47483934599228106 0.1116174975649639 5.4937464084650145 1.2785301217266918 0.04095263522379567 5.329031203735222 6.602242944702625e-05 4.180308498848103 -0.9141362496581519 DKEDPQEMPHS(ph)PLGSMPEIR ddPTM_PC-9_AZD4547_30min_R2 1 DKEDPQEMPHSPLGSMPEIR 20 1 G5E9C0;Q9HB58-2;Q9HB58-5;Q9HB58-3;Q9HB58-7;Q9HB58;Q9HB58-6 G5E9C0 SP110 Sp110 nuclear body protein 1 DKEDPQEMPHS(0.935)PLGS(0.065)MPEIR 42.58 0.029526999999999998 6583800.0 28763.0 24072.0 36988.0 39023.0 38319.0 39570.0 34422.0 36757.0 36688.0 29522.0 True False 37909.03569243398 31852.803246383457 36497.51495247014 30026.850249339983 32999.068284086665 37095.681644656586 37485.491315750136 31077.050241831726 38627.25277996352 28488.443765797467 1.330681170375008 1.1180955866962856 1.2811340364013906 1.0540010713182406 1.1583317276075482 1.302130855220416 1.3158139357810168 1.090865141575128 1.3558919924695383 1.0 14.798089193465033 -10.691850338638774 4.9377177032495565 0.9999829821402414 1.2159179090277241 0.28867169638795764 0.10448397663365418 1.885777071138151e-05 3.1737484527517182e-06 0.09746374516094847 0.023636568258924063 2.0330574981502065e-11 10.691850338638774 0.21593492688748273 DKEDPQEMPHS(ph)PLGSMPEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DKEDPQEMPHSPLGSMPEIR 20 1 G5E9C0;Q9HB58-2;Q9HB58-5;Q9HB58-3;Q9HB58-7;Q9HB58;Q9HB58-6 G5E9C0 SP110 Sp110 nuclear body protein 1 DKEDPQEMPHS(0.964)PLGS(0.036)MPEIR 42.58 0.029526999999999998 6201400.0 27258.0 26160.0 25198.0 34181.0 33737.0 34775.0 32950.0 27506.0 32226.0 26264.0 True False 31872.241029959765 28756.99191458296 25798.815883947165 32265.949386297176 27126.47703308091 32951.337782111244 29828.737462658344 26783.996645016017 32697.24428439774 31025.45529429041 1.0272932573474656 0.9268838004731904 0.8315370601086683 1.039983106782483 0.8743297004274093 1.0620742699680947 0.9614278720398893 0.8632910102674644 1.0538844305184134 1.0 14.921164761411779 -5.7890927662527165 24.999079129235827 0.971920536237345 0.9284022810001574 0.07620773115251911 0.0780165508822305 646.0224738526214 584011.3354457619 0.02150074874164735 0.03189805413180976 1.6252015720561857e-06 5.7890927662527165 -0.04351825523718755 DKENGNNS(ph)PLPK ddPTM_PC-9_AZD4547_30min_R2 1 DKENGNNSPLPK 12 1 Q6P1L5 Q6P1L5 FAM117B Protein FAM117B 1 DKENGNNS(1)PLPK 61.435 0.026344 20947000.0 50501.0 59516.0 64358.0 84296.0 85011.0 95426.0 76242.0 84294.0 78314.0 77565.0 True False 66559.2675139454 78753.38310118625 63504.57086922982 64862.859560217345 73208.6900466736 89458.99713477377 83027.39029967539 71268.29918342001 82453.51815880035 74849.47295894854 0.8892416323418879 1.052156815377696 0.8484304345610975 0.8665773718378967 0.9780788982552377 1.1951853980834024 1.1092581820210285 0.9521549900893406 1.1015911655653512 1.0 16.191704537353672 -6.531294765228558 24.898304447096063 1.072735949756674 0.9196538830558308 0.46701570503208745 0.079600551676728 173.51365911327875 513325.91692132095 0.02690018855002097 0.026942717964144648 2.942423868036674e-07 6.531294765228558 -0.15308206670084312 DKENGNNS(ph)PLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DKENGNNSPLPK 12 1 Q6P1L5 Q6P1L5 FAM117B Protein FAM117B 1 DKENGNNS(1)PLPK 54.598 0.039725 17619000.0 73166.0 74729.0 64879.0 83628.0 102600.0 80321.0 82955.0 74846.0 74167.0 80257.0 True False 85551.5587056292 82147.60125324411 66425.96141497763 78942.59428563403 82496.26652026252 76108.82536296059 75096.90185780967 72881.3718058921 75251.55206482126 94806.95878593755 0.9023763635198351 0.8664722748751311 0.7006443647766329 0.832666665997342 0.8701499085792737 0.802776782818284 0.79210326772921 0.7687344129501007 0.7937344792878549 1.0 16.53270533569313 DKENGNNS(ph)PLPK ddPTM_PC-9_Lapatinib_30min_R1 1 DKENGNNSPLPK 12 1 Q6P1L5 Q6P1L5 FAM117B Protein FAM117B 1 DKENGNNS(1)PLPK 53.49100000000001 0.042395999999999996 19294000.0 61985.0 58721.0 48683.0 53961.0 56761.0 48076.0 46311.0 44993.0 48190.0 42599.0 True False 61101.082533343186 58585.035132307494 44680.47166181446 57929.47194861907 53422.429576419614 46019.90155062974 48708.75697853669 47083.539035021924 42762.334736803175 49962.18039040048 1.2229466779853124 1.172587638780548 0.8942858640812877 1.1594664503422953 1.0692573694538754 0.9210947398819249 0.9749125558158263 0.9423835922915077 0.855894086340142 1.0 15.608548818260289 -1.5228787452803458 0.33630229249426197 0.9298058730398331 4.149862973937256 0.52013608983746 0.08407526003056595 48.733483259263636 0.6918927979749788 0.0762482905461036 98.16586101133196 0.02999999999999943 1.5228787452803458 3.2200571008974226 DKEVS(ph)DDEAEEK ddPTM_PC-9_AZD4547_30min_R2 2 DKEVSDDEAEEK 12 1 P07900;P07900-2;G3V2J8 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 DKEVS(1)DDEAEEK;DKEVS(1)DDEAEEK 65.704 0.020523 5953700.0 59113.0 75070.0 45598.0 52158.0 50511.0 65578.0 74248.0 62245.0 63349.0 56775.0 True False 77909.70437321736 99334.90942613839 44993.34072679609 40133.77893306704 43498.41953332554 61477.39729323447 80855.92816256512 52626.46549780491 66697.49881045317 54787.32453096503 1.422038857348909 1.813100206599716 0.821236319020588 0.7325376677297682 0.7939504238565408 1.122109864271403 1.4758145037154804 0.960559142983176 1.2173892297433992 1.0 15.741554532743377 -5.261467669696777 24.999999999116174 1.0162772474800994 1.6175695524760532 0.5318318292872741 0.22597200569140916 1.982876060509872 1754168.1448883114 0.06371089661764137 0.147947640364427 5.476868710482925e-06 5.261467669696777 0.6012923049959538 DKEVS(ph)DDEAEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DKEVSDDEAEEK 12 1 P07900;P07900-2;G3V2J8 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 DKEVS(1)DDEAEEK 76.158 0.0089459 9942600.0 39346.0 79402.0 37643.0 41486.0 34087.0 29538.0 40095.0 30112.0 29327.0 28407.0 True False 46006.500681076985 87284.50581046325 38540.55188187248 39161.673919426714 27407.897045576934 27988.97528132284 36296.911337337966 29321.591906301255 29755.85189376693 33556.964230311714 1.3709971010881763 2.6010846872620235 1.148511278235924 1.167020760598252 0.8167573460301161 0.8340735201559336 1.0816506251346563 0.8737855935077499 0.8867265730458634 1.0 15.034324586150325 -5.425064148054179 6.210774676441002 0.956316304729085 1.9812267084922817 0.6571497213567896 0.29455008779344066 0.12137214683262314 6.399270743710147 0.07196453693100237 0.15141333683389405 3.7578189481567625e-06 5.425064148054179 1.0249104037631966 DKEVS(ph)DDEAEEK ddPTM_PC-9_Lapatinib_30min_R1 2 DKEVSDDEAEEK 12 1 P07900;P07900-2;G3V2J8 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 DKEVS(1)DDEAEEK;DKEVS(1)DDEAEEK 91.65700000000001 0.0029656999999999995 78800000.0 243616.0 304244.0 142771.0 184539.0 206935.0 198320.0 236841.0 242672.0 169207.0 191111.0 True False 240141.99116629668 303539.541710696 131032.91949199772 198110.61366405766 194763.4901498633 189838.31590649992 249103.4681080868 253947.42703769074 150149.12583129818 224144.28171059917 1.0713723737835648 1.3542149699032116 0.5845918463410951 0.8838530795973885 0.8689201824088001 0.8469469506770959 1.1113532150229615 1.1329641117749838 0.6698771197079262 1.0 17.774068168770796 -5.240170946369643 24.995373821614525 0.8978412970135793 1.212793667717748 0.3559981103531219 0.17464872466644582 920.3740044160112 1081650.4911901748 0.04466985001491648 0.11793568475112066 5.752134780684606e-06 5.240170946369643 0.3149523707041687 DKFS(ph)PFPVQDRPESSLVFK ddPTM_PC-9_AZD4547_30min_R2 1 DKFSPFPVQDRPESSLVFK 19 2 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 DKFS(1)PFPVQDRPESSLVFK 47.64 0.024899 56120000.0 37155.0 44390.0 49516.0 51439.0 54720.0 47117.0 45777.0 49575.0 46989.0 50280.0 True False 48969.51712799031 58738.19940623798 48859.385486820334 39580.53327462775 47123.07253595403 44170.76654160437 49851.06431820041 41914.322870169155 49472.74261005523 48519.712504040894 1.009270554187887 1.2106048526430584 1.0070007212584196 0.8157619085507017 0.9712149991001998 0.9103674416439642 1.0274394003065999 0.8638617317997995 1.0196421218681988 1.0 15.566283381569635 -5.515651804671661 24.97041136578087 0.9392503429172662 1.1096539971920854 0.41499404614695 0.07809441528488659 257.1110997304264 888365.0161646446 0.019432026808613008 0.03551664366161982 3.050339617381746e-06 5.515651804671661 0.17040365427481918 DKFS(ph)PFPVQDRPESSLVFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DKFSPFPVQDRPESSLVFK 19 2 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 DKFS(0.999)PFPVQDRPESSLVFK 50.077 0.019632 44350000.0 75442.0 74695.0 79773.0 81824.0 107260.0 79527.0 84848.0 80262.0 70218.0 68674.0 True False 88212.84055257984 82110.2259579423 81675.09086078715 77239.66655698705 86243.17297235274 75356.46412071773 76810.5831936764 78155.20754461836 71244.80541059513 81124.05257691507 1.0873820741258429 1.0121563623820717 1.0067925389125456 0.9521179490355814 1.0631023751011963 0.9289040885780578 0.94682872408095 0.9634036400057566 0.8782204925357586 1.0 16.307842103963935 -1.5228787657521299 0.35810189857237734 0.943839406185666 2.6139646554839606 0.4456944203094627 0.044397468316054414 58.27597458493511 0.8148439314028016 0.035883975412567694 66.2228362661743 0.02999999858585872 1.5228787657521299 1.6701252492982945 DKFS(ph)PFPVQDRPESSLVFK ddPTM_PC-9_Lapatinib_30min_R1 1 DKFSPFPVQDRPESSLVFK 19 2 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 DKFS(1)PFPVQDRPESSLVFK 45.047 0.030501999999999998 13965000.0 32233.0 23790.0 33182.0 30545.0 31572.0 28880.0 31181.0 24115.0 34627.0 27839.0 True False 31773.351509191732 23734.915716653246 30453.90404622411 32791.38119513297 29714.997032940246 27644.869722568168 32795.399610195265 25235.470936135713 30726.942621524842 32650.934056864233 0.9731222835419006 0.7269291492646727 0.9327115724526037 1.0043014738268785 0.910081070917885 0.8466792917599968 1.004424545805625 0.7728866467399097 0.9410739235824431 1.0 14.99483664360081 -12.491471439964082 1.351639903078663 3.077622395586352 0.8980767407145807 0.0987756489971634 0.08889496248915363 1291087.4793410164 26552.09918939709 8225320.329100369 0.024430982953521925 3.2249913939464305e-13 12.491471439964082 -2.179545654871771 DKGEYTLVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DKGEYTLVVK 10 1 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 91.469 0.010437 6781200.0 55255.0 57063.0 52815.0 70156.0 74366.0 66669.0 64479.0 67797.0 59246.0 50550.0 False True 64608.58016400423 62727.83752377093 54074.3099020029 66225.38676882072 59794.516140797816 63172.760275933135 58371.08233246575 66017.40058685932 60112.36066757986 59714.3148464202 1.0819613409309248 1.0504656661489165 0.9055502025113595 1.10903703641491 1.0013430832219021 1.0579165219999214 0.9775056865776803 1.1055540159281754 1.0066658358583431 1.0 15.865789198516538 DKGEYTLVVK ddPTM_PC-9_Lapatinib_30min_R1 2 DKGEYTLVVK 10 1 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 77.744 0.02767 20336100.0 178285.0 152330.0 140441.0 141410.0 157323.0 159375.0 137371.0 142679.0 156896.0 124586.0 False True 175742.6232065353 151977.28924412752 128894.48309793713 151809.76312993138 148069.57044891865 152558.9027712706 144483.3982185349 149308.38721529747 139224.72029187516 146120.52409958965 1.202723739799595 1.0400817419772335 0.8821107362719836 1.0389352492772623 1.0133386213972284 1.044062110448583 0.9887960579723971 1.0218166690500994 0.9528074248966244 1.0 17.15679930786287 -4.800170770619398 4.006720030042969 0.9956725737131472 1.21710458781132 0.6601301717097834 0.045027669363843954 0.12930149307428526 3.8208689052796996 0.011222250909824006 0.07931323613430706 1.584270112965265e-05 4.800170770619398 0.2214320140981728 DKHIEEVR ddPTM_PC-9_AZD4547_30min_R2 2 DKHIEEVR 8 1 P16949 P16949 STMN1 Stathmin 0 ; 78.264 0.010081 13939200.0 83093.0 100521.0 116466.0 150741.0 133761.0 117095.0 101451.0 152443.0 110202.0 119631.0 False True 109514.84555823189 133012.44745470726 114921.58474246738 115989.99137523396 115190.59403292665 109773.0311392737 110479.94246337136 128886.43714164826 116027.05273815794 115442.75510284252 0.9486506577278951 1.1521939799185554 0.9954854649829619 1.0047403258169292 0.9978157046781218 0.9508871391841097 0.9570106185091475 1.116453232832406 1.0050613625324074 1.0 16.81681811047504 -4.475364534325346 23.717502865812744 1.019475905451928 6.231689729241239e-07 0.10879147813109091 0.06121597261047618 385.41062843791957 658527.0001908714 0.015003733411465723 88313.96041726069 3.3468439674652736e-05 4.475364534325346 -1.0194752822829551 DKHIEEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DKHIEEVR 8 1 P16949 P16949 STMN1 Stathmin 0 ;; 76.1 0.01146 14080000.0 97320.0 124634.0 122555.0 127369.0 123459.0 119974.0 129258.0 105681.0 101642.0 90730.0 False True 113794.35384238328 137006.83984258887 125477.1759924259 120232.92786586977 99268.0952078472 113682.35223784372 117013.74649311973 102906.98572827507 103128.32196222812 107178.63078171543 1.0617261389925918 1.278303695833014 1.1707294175830447 1.1217994388334862 0.9261929778709418 1.0606811395955789 1.0917637745478845 0.9601446200396031 0.9622097353740565 1.0 16.709657765135447 -6.0544970487740395 4.721932087013358 1.0059706755145894 1.177188367484522 0.5783429499276826 0.06675218581807664 0.15102485957026313 7.130281871318143 0.020004273099956338 0.026974673895154736 8.820697961765355e-07 6.0544970487740395 0.17121769196993264 DKHIEEVR ddPTM_PC-9_Lapatinib_30min_R1 3 DKHIEEVR 8 1 P16949 P16949 STMN1 Stathmin 0 ;; 93.14299999999999 0.0033548000000000002 16988800.0 136556.0 160792.0 168401.0 140594.0 165951.0 166707.0 163806.0 165472.0 172584.0 140165.0 False True 134608.68639869642 160419.69600303101 154555.71982665834 150933.75176783543 156190.08845221926 159577.3302229977 172287.0731710864 173160.433205235 153145.77252991145 164392.3334918773 0.8188258146803877 0.9758344114688136 0.9401637931874421 0.9181313298609095 0.9501056718069927 0.9707102930738707 1.048023770400456 1.0533364271138042 0.9315870714705711 1.0 17.326783494313162 -6.786715206199521 2.0880724395079624 1.0120206184109084 0.9205665552268302 0.4200177454752805 0.04900283052716372 0.31747285860074725 2.8471058000733067 0.019391171519557156 0.017535783870245084 1.6341231924420738e-07 6.786715206199521 -0.09145406318407823 DKHIEEVRK ddPTM_PC-9_AZD4547_30min_R2 1 DKHIEEVRK 9 2 P16949 P16949 STMN1 Stathmin 0 45.972 0.035394999999999996 13271000.0 53725.0 51732.0 67684.0 90695.0 79377.0 87079.0 57033.0 71044.0 63075.0 63163.0 False True 70808.43245057933 68453.35732560274 66786.46593606005 69786.66897378191 68356.87369675492 81633.93636429234 62108.82651243904 60065.782228710035 66409.01572983545 60951.68259532096 1.1617141551399115 1.1230757611744364 1.0957280109800775 1.144950656032245 1.1214928085020974 1.339322113653333 1.0189846099048774 0.9854655305827614 1.0895353975828295 1.0 15.895378427112236 DKKS(ph)PLIESTANMDNNQSQK ddPTM_PC-9_AZD4547_30min_R2 1 DKKSPLIESTANMDNNQSQK 20 2 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 DKKS(0.966)PLIES(0.008)T(0.026)ANMDNNQSQK 50.943999999999996 0.014765 21131000.0 37975.0 29912.0 39253.0 56931.0 66280.0 48748.0 43972.0 51244.0 54238.0 53627.0 True False 50050.26007093073 39580.469038958996 38732.479572545424 43806.43752518192 57078.16607607884 45699.77985377099 47885.42281494871 43325.41726997378 57104.90995092842 51749.53505278841 0.9671634734471665 0.7648468531859068 0.7484604360799646 0.8465088136636604 1.1029696405553178 0.8830954675661102 0.9253304936189666 0.83721365275608 1.103486435050617 1.0 15.659258280228084 -6.024119939690266 24.33874215802291 0.9614275236966704 0.8167690159110051 0.3381964572441495 0.09723744099802759 622.9513464291903 628602.3021708075 0.028219456821295345 0.0366542557009298 9.459758738599918e-07 6.024119939690266 -0.14465850778566525 DKKS(ph)PLIESTANMDNNQSQK ddPTM_PC-9_Lapatinib_30min_R1 2 DKKSPLIESTANMDNNQSQK 20 2 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 DKKS(0.865)PLIES(0.058)T(0.075)ANMDNNQS(0.002)QK;DKKS(0.82)PLIES(0.09)T(0.09)ANMDNNQSQK 47.222 0.022633 34552000.0 128213.0 75173.0 83193.0 73066.0 96287.0 95914.0 80707.0 81306.0 87937.0 91139.0 True False 126384.6591086151 74998.94153711542 76353.19267426665 78439.5173810307 90623.58796752561 91811.98180645444 84885.61355761603 85083.77358214589 78032.6090423378 106892.25471491614 1.1823556294671267 0.7016312055269033 0.7143005157661068 0.7338185314757418 0.8478031285729785 0.8589208081663063 0.7941231456292855 0.7959769752173914 0.7300118165759755 1.0 16.70579779532308 -4.753496471316036 24.999810426777806 0.7898344181690826 1.1823563423646912 0.6467664090337445 0.08518259483407588 177.20919014049466 557710.5662884013 0.02066971693808545 0.22131299145373973 1.7640200972492226e-05 4.753496471316036 0.3925219241956086 DKLCS(ph)PLSEPGDPSK ddPTM_PC-9_AZD4547_30min_R2 2 DKLCSPLSEPGDPSK 15 1 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 DKLCS(0.893)PLS(0.107)EPGDPSK;DKLCS(0.999)PLS(0.001)EPGDPSK 102.07 0.00073226 18760000.0 112776.0 96385.0 107606.0 156459.0 164387.0 165183.0 113413.0 136883.0 114071.0 141533.0 True False 148636.422113477 127539.5663385952 106179.0741314886 120389.79481745334 141564.70257616727 154854.08089737967 123506.53728990653 115730.87760841862 120100.560179438 136577.97274929273 1.0882898546628683 0.9338223709961727 0.7774245875386845 0.8814729959306471 1.0365119625551065 1.133814463490648 0.9042932385342943 0.8473612199593725 0.8793552705596148 1.0 17.05936529944224 -11.906153922413111 2.166425557189058 1.4057113778428685 0.9400511439535827 0.02537916651386607 0.10596946008887276 19813690.432989 3023531.6399510317 39047930.21002786 0.03060836291968785 1.241212319834328e-12 11.906153922413111 -0.4656602338892858 DKLCS(ph)PLSEPGDPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DKLCSPLSEPGDPSK 15 1 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 DKLCS(1)PLSEPGDPSK;DKLCS(0.998)PLS(0.002)EPGDPSK 83.25299999999999 0.0032844000000000003 9812300.0 112298.0 113572.0 93617.0 159308.0 150392.0 142818.0 176363.0 129261.0 150890.0 133567.0 True False 131307.8334133989 124846.67758880048 95849.18432444974 150382.48924350465 120923.76719800539 135328.37266328 159656.61988245248 125868.03571335069 153096.48079416578 157781.63978420992 0.8322123765032616 0.7912623912360592 0.6074799606312743 0.9531051233158387 0.7663994832566501 0.8576940437959819 1.01188338580336 0.797735629351388 0.970306057178441 1.0 17.26756981075551 -7.084446950167038 0.48178316289124684 0.9799935174705038 0.7522098740462367 0.3578815111360121 0.09662404901479578 1.1950995555114756 0.6008803433321803 0.09290210974530838 0.09919377057969966 8.232903971459942e-08 7.084446950167038 -0.22778364342426705 DKLCS(ph)PLSEPGDPSK ddPTM_PC-9_Lapatinib_30min_R1 2 DKLCSPLSEPGDPSK 15 1 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 DKLCS(0.999)PLS(0.001)EPGDPSK;DKLCS(1)PLSEPGDPSK 81.643 0.011864 10196000.0 128889.0 148833.0 140147.0 130528.0 179272.0 189740.0 180911.0 201966.0 186927.0 178545.0 True False 127051.01922465205 148488.3863327721 128624.65464306432 140127.4645486432 168727.5734223127 181625.26250554287 190277.68637567872 211350.07767313247 165873.3128314256 209406.26535374194 0.6067202383368504 0.7090923764001825 0.6142349868366338 0.6691655777917211 0.8057427180475604 0.8673344238231377 0.9086532633312091 1.0092824936068983 0.7921124640240453 1.0 17.67594508222392 -6.5181680316946276 1.5370175743002195 0.9262169710123916 0.6439109181894433 0.8059148223806164 0.06190488711797221 0.1595468801439104 0.7690857000444583 0.023769982330137877 0.026305532390220373 3.032717576676225e-07 6.5181680316946276 -0.2823060528229483 DKLESEMEDAYHEHQANLLR ddPTM_PC-9_AZD4547_30min_R2 1 DKLESEMEDAYHEHQANLLR 20 1 P23246;P23246-2;H0Y9K7 P23246 SFPQ Splicing factor, proline- and glutamine-rich 0 50.966 0.011904000000000001 7371400.0 20999.0 20036.0 29703.0 47278.0 27278.0 30086.0 29728.0 41303.0 25144.0 27888.0 False True 27676.24519366624 26512.2451746651 29309.118812404588 36378.7875378186 23490.920552553962 28204.717663915544 32373.734409233053 34920.57039851935 26473.060507506638 26911.64960844656 1.0284113235845527 0.9851586788772657 1.0890866683700262 1.351785864750582 0.8728903985573979 1.0480486359729928 1.2029635819527074 1.2976005152638093 0.9837026303730461 1.0 14.71594320638745 -7.241449845039521 23.7425270726626 1.145866733508871 1.0647757349488551 0.027614458918027163 0.14198040644824214 1308.8291506714477 1554559.6805490684 0.055050404966386024 0.042574559139812194 5.7352209653131e-08 7.241449845039521 -0.08109099856001589 DKLESEMEDAYHEHQANLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DKLESEMEDAYHEHQANLLR 20 1 P23246;P23246-2;H0Y9K7 P23246 SFPQ Splicing factor, proline- and glutamine-rich 0 ; 89.311 0.00017982 14475800.0 66860.0 62968.0 66369.0 69886.0 83616.0 73870.0 76213.0 79202.0 61819.0 53795.0 False True 78178.07745480644 69219.04689898551 67951.48866583416 65970.51399346892 67232.04504247852 69996.12715929713 68993.55290566258 77123.03142145566 62722.985924942106 63547.60765901428 1.2302284906506125 1.0892470928316171 1.069300500350074 1.0381274201139963 1.057979167417825 1.101475409347973 1.0856986666731867 1.2136260397918488 0.9870235597459946 1.0 15.955550193474535 -14.522756747277517 0.01244779290082928 4.504011391427742e-05 1.9650717834355464 0.20611146608815978 0.06778217733999307 17924.56905934435 16.876003421366956 1606.3526844255769 1101.7931240635187 3.0008428507253923e-15 14.522756747277517 1.9650267433216322 DKLNNLVLFDK ddPTM_PC-9_AZD4547_30min_R2 2 DKLNNLVLFDK 11 1 P62851 P62851 RPS25 40S ribosomal protein S25 0 ; 90.79299999999999 0.021062 2494100.0 52669.0 47846.0 74387.0 106528.0 93757.0 80341.0 58323.0 85323.0 68955.0 79103.0 False True 69416.64641674391 63311.28382047451 73400.57977639757 81969.61544119347 80740.45891362273 75317.26456945548 63513.63401337791 72138.29087748735 72599.82052557752 76333.62804707928 0.9093848699806424 0.82940226267546 0.9615759351976204 1.0738336109301414 1.0577311858389005 0.986685246022933 0.8320531283303532 0.9450394632493502 0.9510856798369532 1.0 16.220031142097774 -5.354173727324029 6.331937066456127 0.976372955531533 0.8700780624646189 0.3009662783596374 0.06521029270400885 0.3030594745543208 17.003699537799637 0.019336774674567014 0.040890010624210785 4.424113627066256e-06 5.354173727324029 -0.10629489306691409 DKLNNLVLFDK ddPTM_PC-9_Lapatinib_30min_R1 2 DKLNNLVLFDK 11 1 P62851 P62851 RPS25 40S ribosomal protein S25 0 ; 131.13 0.00022581 6584300.0 116596.0 100560.0 115388.0 96993.0 104687.0 102250.0 90905.0 101091.0 104349.0 92944.0 False True 114933.31965891217 100327.15949838783 105901.24405056088 104126.18877916283 98529.51648256094 97877.00585639165 95611.61609841883 105788.05691083964 92596.11677631618 109009.24655990461 1.0543446843819075 0.9203545815102423 0.9714886341532893 0.9552051047517481 0.9038638426733399 0.8978780144361848 0.8770963850839636 0.9704503081094611 0.8494336003453724 1.0 16.73409098925857 -1.5228787726925532 0.9091253390011544 0.9188832517722761 66.96933261734299 0.39033024670943006 0.045829044255091045 973.9833999319113 2.044713581527928 0.014444806463568514 133538.12646530027 0.029999998106431284 1.5228787726925532 66.05044936557071 DKLVY(ph)VHT(ph)NGPK ddPTM_PC-9_AZD4547_30min_R2 1 DKLVYVHTNGPK 12 1 H7BXY3;Q7L2E3-3;Q7L2E3;Q7L2E3-2 H7BXY3 DHX30 Putative ATP-dependent RNA helicase DHX30 2 DKLVY(1)VHT(1)NGPK 61.435 0.028505000000000003 26302000.0 28387.0 28163.0 35518.0 40516.0 40149.0 38432.0 26785.0 30142.0 30182.0 36792.0 True False 37413.47551371983 37266.138992518136 35047.00811295109 31175.66216596004 34575.00437218599 36028.84096455503 29168.813110579486 25484.246494253926 31777.358902225795 35503.92327861323 1.0537842598442317 1.0496343939253165 0.9871305725264066 0.8780906245575278 0.9738361617352076 1.014784779750186 0.8215659120734449 0.717786772303135 0.8950379554635802 1.0 15.115690834641699 -7.2642065040495165 24.82559874126767 0.835079883114604 0.9891124624721772 0.383755735590088 0.08111810870108024 212.77764603079257 1908944.3363085473 0.03334698962074474 0.023618780380940695 5.442438071075467e-08 7.2642065040495165 0.1540325793575732 DKLVY(ph)VHT(ph)NGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DKLVYVHTNGPK 12 1 H7BXY3;Q7L2E3-3;Q7L2E3;Q7L2E3-2 H7BXY3 DHX30 Putative ATP-dependent RNA helicase DHX30 2 DKLVY(1)VHT(1)NGPK;DKLVY(1)VHT(1)NGPK 63.408 0.024327 22718700.0 62227.0 64861.0 65283.0 95764.0 83235.0 74840.0 86068.0 74839.0 65620.0 60462.0 True False 72760.80206072735 71299.97142858431 66839.5943071561 90398.65355107699 66925.6992574471 70915.25865170974 77915.01596164131 72874.5555484751 66579.56835915659 71423.28198307139 1.0187266678388285 0.9982735243877997 0.9358236201326943 1.2656748757709442 0.9370291787110777 0.9928871466382341 1.090891006382325 1.020319334607834 0.9321829872636931 1.0 16.12410680851561 -8.102750740353594 6.585739807697019 0.96744588933292 1.0341453541828625 0.08116605648471753 0.09026010130465188 0.6626859228830033 36.07355108132439 0.06125675240288458 0.022801675593951836 7.893130071677486e-09 8.102750740353594 0.06669946484994249 DKMAEAYS(ph)EIGMKGER ddPTM_PC-9_Lapatinib_30min_R1 1 DKMAEAYSEIGMKGER 16 2 P20963-3;P20963 P20963-3 CD247 T-cell surface glycoprotein CD3 zeta chain 1 DKMAEAY(0.087)S(0.913)EIGMKGER 83.85600000000001 0.015749000000000003 0.0 12526.0 17596.0 25730.0 18983.0 24043.0 20480.0 22648.0 21627.0 25849.0 17014.0 True False 12347.376943012934 17555.25754309502 23614.578720672227 20379.073145431623 22628.83801035671 19604.11814121176 23820.60262248492 22631.86937324515 22937.613417962755 19954.84723027005 0.6187657966272406 0.8797490324288212 1.1834006268336963 1.0212592915528842 1.1340020672285784 0.982423864988239 1.193725130922115 1.1341539783333572 1.1494757716394874 1.0 14.284451613498836 -4.933973631005964 2.715603655686053 1.1018992652098147 0.5952991456044164 0.8107341276521004 0.07295369377766618 0.12849371517122415 1.6099277456495629 0.01834255836824655 0.12694759970776157 1.164196713624849e-05 4.933973631005964 -0.5066001196053983 DKNNKEPIIEDILNLESSPT(ph)ASGSSVSPGLYSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DKNNKEPIIEDILNLESSPTASGSSVSPGLYSK 33 2 Q9BQL6-4;Q9BQL6-2;Q9BQL6 Q9BQL6-4 FERMT1 Fermitin family homolog 1 1 DKNNKEPIIEDILNLES(0.005)S(0.014)PT(0.389)AS(0.311)GS(0.093)S(0.093)VS(0.093)PGLY(0.002)S(0.001)K 49.588 0.003768 1228500.0 7111.4 7118.3 8520.4 9964.1 12214.0 13270.0 14446.0 12500.0 14686.0 12514.0 True False 8315.219563447641 7824.957780794181 8723.558649796942 9405.843781048063 9820.754378932634 12574.097839500108 13077.570300017062 12171.888244844778 14900.75496681764 14782.689139230497 0.5624970859585081 0.5293324987825256 0.5901198738358264 0.6362742050826672 0.6643415339682809 0.8505961074518438 0.8846543532672707 0.8233879594033308 1.0079867625216996 1.0 13.851621115538135 -6.78291423092227 0.5966309707694241 0.9893972270901277 0.5148228160126139 0.9326213660074084 0.04436637690673288 0.20107446994110387 0.1556879228647395 0.03664873620646451 0.040855834098272314 1.6484879202481876e-07 6.78291423092227 -0.47457441107751375 DKPASSMS(ph)DDEMPVLEIPR ddPTM_PC-9_AZD4547_30min_R2 1 DKPASSMSDDEMPVLEIPR 19 1 Q96PN7 Q96PN7 TRERF1 Transcriptional-regulating factor 1 1 DKPAS(0.031)S(0.074)MS(0.896)DDEMPVLEIPR 46.876999999999995 0.040538 6380100.0 21231.0 16638.0 20546.0 30805.0 26696.0 27033.0 22147.0 28849.0 24433.0 24319.0 True False 27982.01636776644 22015.908126176782 20273.54661548207 23703.383182505662 22989.721206502698 25342.622236542877 24118.040095576027 24391.049934069782 25724.478499041896 23467.599212127498 1.192368086519306 0.9381406221902531 0.8638952128092073 1.010047213106329 0.9796366896628333 1.0798983742421513 1.0277165498510985 1.0393500295277358 1.0961700115343753 1.0 14.518382638030937 -6.7481165978635325 24.82635963988819 1.0497794677443357 0.9869081265466682 0.08550872485720529 0.08151399215611196 485.0294314060099 903826.1609756339 0.027329826847856932 0.027174233223653057 1.7860080092952156e-07 6.7481165978635325 -0.06287134119766757 DKPTYDEIFYTLS(ph)PVNGK ddPTM_PC-9_AZD4547_30min_R2 3 DKPTYDEIFYTLSPVNGK 18 1 A0A024R571;Q9H4M9 A0A024R571 EHD1 EH domain-containing protein 1 1 DKPTYDEIFYT(0.007)LS(0.993)PVNGK;DKPTYDEIFYT(0.001)LS(0.999)PVNGK;DKPTYDEIFY(0.024)T(0.005)LS(0.971)PVNGK 120.23 3.8122e-05 208887000.0 256280.0 245856.0 282126.0 349673.0 291498.0 301682.0 256734.0 306714.0 250897.0 290590.0 True False 337771.70904484956 325324.14402388065 278384.82490214607 269061.2922439961 251028.53432173803 282817.7768492106 279582.82864033995 259318.39888655712 264158.903203623 280416.53254871274 1.204535645508609 1.16014609077076 0.992754679518713 0.9595058101549556 0.8951987674911087 1.0085631338447592 0.9970269088602044 0.9247614487263138 0.9420232851561079 1.0 18.09721188342487 -5.248695419822275 2.6989553316831807 0.9588168759248501 1.2012517985656126 0.873719690712909 0.0334391478534625 0.09139962078371967 1.2917794494526216 0.009423234191440553 0.030417221706725096 5.640330858338683e-06 5.248695419822275 0.2424349226407625 DKPTYDEIFYTLS(ph)PVNGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DKPTYDEIFYTLSPVNGK 18 1 A0A024R571;Q9H4M9 A0A024R571 EHD1 EH domain-containing protein 1 1 DKPTYDEIFYT(0.004)LS(0.996)PVNGK;DKPTYDEIFYT(0.002)LS(0.998)PVNGK 126.61 2.0581999999999997e-05 122510000.0 330690.0 359810.0 317030.0 362630.0 363080.0 347690.0 344439.0 355498.0 317050.0 250586.0 True False 386669.28557478136 395529.5588985516 324589.19754297007 342313.0167623232 291937.08039158856 329456.5243267363 311811.2443975893 346166.55418126594 321686.25645032973 296015.2581623154 1.3062478197078518 1.336179632610928 1.0965286031471613 1.1564032843692846 0.9862230825666066 1.1129714271217865 1.0533620676627837 1.1694213208139792 1.0867218752417755 1.0 18.175312016195655 -5.265483907036631 21.72878405520078 1.087974099913449 1.3212138165527585 0.7408883456643225 0.05635111357958419 24.17546432993978 129887.64002227332 0.014165290459066678 0.03150638991137222 5.426453589068233e-06 5.265483907036631 0.23323971663930942 DKPTYDEIFYTLS(ph)PVNGK ddPTM_PC-9_Lapatinib_30min_R1 2 DKPTYDEIFYTLSPVNGK 18 1 A0A024R571;Q9H4M9 A0A024R571 EHD1 EH domain-containing protein 1 1 DKPTYDEIFYTLS(1)PVNGK;DKPTYDEIFYTLS(1)PVNGK 121.25 3.3123e-05 124570000.0 521360.0 473430.0 499830.0 461560.0 460930.0 442120.0 396530.0 372870.0 459920.0 344720.0 True False 513925.3107942861 472333.801922453 458735.9067995964 495504.6621190244 433819.00362324674 423211.55823205825 417060.3831638089 390194.9014288583 408118.96642769256 404304.3926894728 1.2711346205654706 1.1682628496327774 1.1346300339406152 1.2255732835917965 1.0730009652812322 1.0467646799897796 1.03155046223832 0.9651018106265015 1.0094349054999003 1.0 18.62508235273574 -6.55022560881257 0.9999053479701298 0.9907518364877583 1.207691117457555 0.8379776087578088 0.03923422444942393 0.2048805636924333 0.442050014306277 0.020402661319519608 0.023173516486025367 2.8169192080898333e-07 6.55022560881257 0.21693928096979676 DKPVYDELFYT(ph)LSPINGK ddPTM_PC-9_AZD4547_30min_R2 1 DKPVYDELFYTLSPINGK 18 1 Q9H223 Q9H223 EHD4 EH domain-containing protein 4 1 DKPVYDELFY(0.027)T(0.861)LS(0.112)PINGK 70.917 0.0068747 14399000.0 40239.0 39278.0 40323.0 52134.0 47642.0 40876.0 36556.0 42779.0 41237.0 47926.0 True False 53034.1649768053 51973.84537684648 39788.290673419855 40115.31176227072 41027.730660780726 38320.0172582002 39809.41318164434 36168.48851362517 43416.703632995974 46248.12532753909 1.1467311291259057 1.1238043706367906 0.8603222377475993 0.8673932506056304 0.8871220264651504 0.8285744986809662 0.8607789591406264 0.7820530725834229 0.9387775899133125 1.0 15.497107266573488 -5.250186617149609 6.732027124571632 0.8676583681602081 1.1373348759416488 0.7655990991606894 0.05668639722764533 0.058945225577311314 14.62359551596159 0.013646084370357262 0.0337024726906729 5.62099737982098e-06 5.250186617149609 0.2696765077814407 DKQPYEQK ddPTM_PC-9_Lapatinib_30min_R1 1 DKQPYEQK 8 1 P26583 P26583 HMGB2 High mobility group protein B2 0 78.149 0.029213 3586300.0 25393.0 19953.0 19870.0 25357.0 21499.0 20040.0 21378.0 23521.0 22189.0 17524.0 False True 25030.89116349412 19906.80005440866 18236.365300418092 27221.8383684723 20234.47108866027 19182.93591552168 22484.848236642636 24613.871527632098 19689.841159471376 20553.00005073777 1.2178704374885463 0.9685593346599581 0.8872848370261879 1.3244703109653886 0.9845020697080149 0.9333399439578696 1.09399348908363 1.1975804732578959 0.9580032652588151 1.0 14.327061374060944 DKRPLS(ph)GPDVGTPQPAGLASGAK ddPTM_PC-9_AZD4547_30min_R2 1 DKRPLSGPDVGTPQPAGLASGAK 23 2 O96013 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 DKRPLS(1)GPDVGTPQPAGLASGAK 94.01899999999999 3.0153e-05 83720000.0 66538.0 60582.0 90542.0 109370.0 112690.0 91105.0 82579.0 110550.0 86901.0 97653.0 True False 87695.69992362337 80163.94675441999 89341.3539209081 84156.43624965572 97044.93867099151 85408.18994785019 89928.3710232798 93467.03768627734 91494.4094480924 94234.19819325993 0.9306143799703468 0.8506884792505581 0.9480778277296174 0.8930562138074729 1.0298271809133155 0.9063396472339166 0.9543071702997936 0.9918590010665845 0.9709257488502354 1.0 16.52396309767075 -5.622275117271532 0.3203177421824515 0.9964406667062241 0.84627936571779 0.35864864810102215 0.04115826264215345 4.511917148455111 0.5659257234747712 0.04543446208886721 0.2531820662594624 2.3862991290160755e-06 5.622275117271532 -0.15016130098843405 DKRPLS(ph)GPDVGTPQPAGLASGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DKRPLSGPDVGTPQPAGLASGAK 23 2 O96013 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 DKRPLS(0.659)GPDVGT(0.341)PQPAGLASGAK;DKRPLS(0.994)GPDVGT(0.006)PQPAGLASGAK 80.132 6.2164e-05 76080000.0 59731.0 60511.0 70221.0 85531.0 95561.0 89212.0 93379.0 80203.0 91455.0 75929.0 True False 69842.27855897442 66518.13217673286 71895.3349546256 80738.97536524337 76836.50804037844 84533.56567124969 84533.46511458485 78097.75623210287 92792.35635913849 89694.32664636672 0.7786699691089497 0.741609136985782 0.8015594479914399 0.9001569930233028 0.8566484739142738 0.9424627937119802 0.9424616726080196 0.8707101012086855 1.034539862537641 1.0 16.452729114103093 -5.292777526805768 0.31186917262129177 1.0027113132712144 0.5986963671508315 0.778143869707399 0.04271018716240172 2.4819192873825777 0.25158686489456056 0.04801959391703795 0.37187523152382773 5.095918494909593e-06 5.292777526805768 -0.4040149461203829 DKRPLS(ph)GPDVGTPQPAGLASGAK ddPTM_PC-9_Lapatinib_30min_R1 1 DKRPLSGPDVGTPQPAGLASGAK 23 2 O96013 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 DKRPLS(1)GPDVGTPQPAGLASGAK 63.606 0.006755800000000001 84137000.0 175540.0 122190.0 123440.0 124380.0 130430.0 109710.0 117920.0 148790.0 134520.0 86558.0 True False 173036.76740990643 121907.0765623313 113291.2396921796 133527.3201195165 122758.36383524635 105017.95904650111 124025.32061300872 155703.32658460006 119368.94104160104 101519.43496871473 1.704469370453364 1.2008250105006932 1.1159561686596522 1.3152882515615423 1.2092104716015886 1.034461618889669 1.221690414758806 1.5337292473365636 1.175823536433068 1.0 16.631396419078136 -4.760498206458625 24.99658277208332 1.2141027939694964 1.7044699470273392 0.5290144209321443 0.14207969808335724 19.434826442423525 515897.7332250379 0.03584096744951789 0.21154262962140719 1.7358084313664258e-05 4.760498206458625 0.49036715305784284 DKRPLSGPDVGT(ph)PQPAGLASGAK ddPTM_PC-9_AZD4547_30min_R2 1 DKRPLSGPDVGTPQPAGLASGAK 23 2 O96013 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 DKRPLS(0.269)GPDVGT(0.731)PQPAGLASGAK 56.882 0.0038692 141910000.0 574360.0 645050.0 864660.0 1066000.0 1054400.0 974510.0 778210.0 1163800.0 814160.0 973320.0 True False 756994.5325698416 853549.7978597386 853194.0434411926 820250.1695358222 908014.7602688214 913573.7356465588 847469.1824074681 983961.4514634961 857194.835459417 939244.3630555524 0.8059612198333401 0.9087622257140495 0.9083834590878772 0.873308589116662 0.9667502898977911 0.9726688512396479 0.9022882816677004 1.0476096425667862 0.9126430449588097 1.0 19.84114102688895 -1.8487211828761734 0.27460017885108934 0.9888285554387553 3.2881250441546095e-14 0.5369301390199263 0.044357473495159255 33.43982371530957 0.5519658731222535 0.04861384885377429 15.230891934082708 0.014167030116126245 1.8487211828761734 -0.9888285554387224 DKS(ph)FDDEESVDGNRPSSAASAFK ddPTM_PC-9_Lapatinib_30min_R1 1 DKSFDDEESVDGNRPSSAASAFK 23 2 E7ERI8;E7EW49;O75122-3 E7ERI8 CLASP2 CLIP-associating protein 2 1 DKS(0.997)FDDEES(0.002)VDGNRPSSAASAFK 40.645 0.033594 5420600.0 14985.0 19685.0 14257.0 19920.0 16251.0 16046.0 11937.0 18234.0 17554.0 20301.0 True False 14771.31115208756 19639.420591942802 13084.844493611508 21384.983251171998 15295.1481306953 15359.749985052924 12555.039451810424 19081.218206489677 15576.883668185148 23810.000800617858 0.6203826398739244 0.8248391403427912 0.5495524592032758 0.8981513033219666 0.6423833522214076 0.6450965757487226 0.5273010932231731 0.801395109822698 0.6542160077449866 1.0 14.539280048668717 -10.637061106191018 3.7213189896822647 1.0001554568206172 0.6876080021094249 0.4066539696194015 0.114172140233144 121181783.40693524 200534732.0785022 228478.81002437902 0.02708799725841838 2.3064226471377224e-11 10.637061106191018 -0.3125474547111924 DKS(ph)PSSLLEDAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DKSPSSLLEDAK 12 1 P42684-2;P42684-6;P42684-3;P42684;P42684-4;P42684-7;P42684-10;P42684-5 P42684-2 ABL2 Abelson tyrosine-protein kinase 2 1 DKS(0.934)PS(0.051)S(0.015)LLEDAK 58.81399999999999 0.031474 11771000.0 57772.0 68248.0 53282.0 62794.0 68373.0 53567.0 65191.0 67922.0 56045.0 49504.0 True False 67551.6585509882 75023.21040468125 54552.44495311023 59275.85576089478 54975.80146968724 50757.85222068588 59015.63653803218 66139.11946930761 56864.55209827692 58478.68332655161 1.1551501283599712 1.2829155195875925 0.932860349274336 1.0136318464951009 0.940099850790007 0.8679718716861026 1.0091820331945944 1.1309953594539612 0.9723979553496238 1.0 15.835623208287833 -5.263268276618423 24.999999528539377 0.9844035241304541 1.2190328333889662 0.6413236413601398 0.07048593943117026 97.43807066560683 1331943.288159651 0.01942875059508905 0.04403511701418359 5.454208343347798e-06 5.263268276618423 0.2346293092585121 DKS(ph)PSSLLEDAK ddPTM_PC-9_Lapatinib_30min_R1 2 DKSPSSLLEDAK 12 1 P42684-2;P42684-6;P42684-3;P42684;P42684-4;P42684-7;P42684-10;P42684-5 P42684-2 ABL2 Abelson tyrosine-protein kinase 2 1 DKS(0.958)PS(0.021)S(0.021)LLEDAK;DKS(0.959)PS(0.02)S(0.02)LLEDAK 115.04 0.0035773000000000003 15945700.0 59231.0 53222.0 45351.0 47192.0 50273.0 56511.0 53252.0 53179.0 49220.0 41187.0 True False 58386.35507836489 53098.767728949955 41622.41583992252 50662.657107897016 47316.04098052084 54094.15626357513 56009.12799596289 55649.89047948416 43676.32529042231 48306.1180717722 1.2086741267765646 1.0992141337057335 0.8616385977875685 1.0487834487677838 0.9795041056749721 1.1198199818748256 1.1594624083174252 1.1520257205681637 0.9041572172189236 1.0 15.559918300553226 -6.77370144019575 24.974165105836654 1.0823677459021794 1.0335044034826433 0.004577903477341105 0.10882622693173474 893.5323390231232 1819847.4834136146 0.03947961104774659 0.035072743299410715 1.6838312288018666e-07 6.77370144019575 -0.04886334241953616 DKS(ph)PVREPIDNLTPEER ddPTM_PC-9_AZD4547_30min_R2 1 DKSPVREPIDNLTPEER 17 2 G3XAC6;Q14498-2;Q14498;Q5QP23;Q5QP22;H0Y4X3;Q14498-3 G3XAC6 RBM39 RNA-binding protein 39 1 DKS(1)PVREPIDNLTPEER 62.165 0.009507700000000001 570180000.0 75345.0 91939.0 81598.0 102360.0 110430.0 101970.0 90232.0 99193.0 65054.0 103410.0 True False 99303.14272664329 121656.48378486396 80515.95720481392 78762.48344623539 95098.70066055188 95593.79978027868 98262.47319745395 83865.00107837988 68492.6216296267 99789.64737555449 0.9951246981855717 1.219129308344126 0.8068568165372428 0.7892851164190993 0.9529916495510962 0.9579530772417214 0.9846960659921657 0.8404178517913505 0.6863700136333517 1.0 16.606602531237556 -5.267719640722694 24.983504986826773 0.877894838295575 1.1071270064521834 0.4247382560256985 0.10697590789892675 428.6123113497115 1705068.1141315482 0.028555051100463892 0.06182042001028281 5.398590166279665e-06 5.267719640722694 0.2292321681566084 DKS(ph)PVREPIDNLTPEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DKSPVREPIDNLTPEER 17 2 G3XAC6;Q14498-2;Q14498;Q5QP23;Q5QP22;H0Y4X3;Q14498-3 G3XAC6 RBM39 RNA-binding protein 39 1 DKS(0.987)PVREPIDNLT(0.013)PEER;DKS(0.999)PVREPIDNLT(0.001)PEER;DKS(0.999)PVREPIDNLT(0.001)PEER 48.31399999999999 0.030412 726415200.0 130706.5 101172.7 91701.0 150757.0 154000.0 135560.0 151695.0 167504.0 124494.0 116281.0 True False 152832.5288789509 111216.4570289194 93887.49961797916 142310.57405078883 123824.80549824968 128450.99496025869 137325.35142330662 163107.1974851585 126314.48923049103 137361.82482011043 1.11262739177425 0.8096605965636297 0.6835050403628126 1.0360271075108336 0.9014499163825984 0.9351287748868989 0.9997344721005885 1.187427421692776 0.9195749211683302 1.0 17.067621584887142 -7.254535431218045 2.8325123957631213 1.0469726621977062 0.8995520553857272 0.16243709327639755 0.1257130212046186 0.4430264473928808 7.132943725396051 0.05718891435765027 0.03895559471954991 5.564992313098945e-08 7.254535431218045 -0.147420606811979 DKS(ph)PVREPIDNLTPEER ddPTM_PC-9_Lapatinib_30min_R1 4 DKSPVREPIDNLTPEER 17 2 G3XAC6;Q14498-2;Q14498;Q5QP23;Q5QP22;H0Y4X3;Q14498-3 G3XAC6 RBM39 RNA-binding protein 39 1 DKS(1)PVREPIDNLTPEER;DKS(0.998)PVREPIDNLT(0.002)PEER;DKS(1)PVREPIDNLTPEER;DKS(0.999)PVREPIDNLT(0.001)PEER 146.1 0.0012341 1314101000.0 182601.0 166980.0 170054.0 152295.4 173879.0 146017.3 143423.0 136293.0 136078.0 130608.7 True False 179997.07625507776 166593.36806922028 156072.8165474234 163495.71175856155 163651.77907926711 139772.48046195135 150848.74116587153 142625.67034205858 120751.46267513369 153184.23976984684 1.1750365215476222 1.0875359522593193 1.01885687967585 1.067314183261981 1.0683330042643246 0.9124468722889109 0.9847536625994665 0.9310727432296424 0.7882760188421335 1.0 17.22490834888314 -6.46411523389055 0.6386685477658753 0.8980420506902256 1.1287286925634736 0.5993789354805554 0.06492544021676258 0.590479265396942 0.5291601663525566 0.046736617205835315 0.06993707789859349 3.4346680175636885e-07 6.46411523389055 0.23068664187324806 DKSDS(ph)PAIQLR ddPTM_PC-9_AZD4547_30min_R2 1 DKSDSPAIQLR 11 1 Q96ST3 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 DKS(0.003)DS(0.997)PAIQLR 52.821000000000005 0.046068 12838000.0 65239.0 55182.0 72593.0 85739.0 88214.0 85680.0 67036.0 69132.0 61070.0 58399.0 True False 85983.64494450156 73018.5023571756 71630.3693885765 65973.19820434519 75967.00878447824 80322.41605545061 73002.07413406037 58449.23789532092 64298.035523123996 56354.468785272176 1.525764447751706 1.2957003043609285 1.2710681323518493 1.1706826384208024 1.3480210251636984 1.425306950572166 1.2954087884710737 1.037171304338445 1.1409571753416619 1.0 15.782242397022793 -7.715199645371692 5.695181155990455 1.0663546070894414 1.3289425346839876 0.6383680388357647 0.09450104133088232 0.12867669834866574 9.598940401357916 0.04849777302990941 0.026777696031781564 1.926639032743381e-08 7.715199645371692 0.2625879275945462 DKSPVREPIDNLT(ph)PEER ddPTM_PC-9_Lapatinib_30min_R1 1 DKSPVREPIDNLTPEER 17 2 G3XAC6;Q14498-2;Q14498;Q5QP23;Q5QP22;H0Y4X3;Q14498-3 G3XAC6 RBM39 RNA-binding protein 39 1 DKS(0.148)PVREPIDNLT(0.852)PEER 103.46 0.0036325000000000003 23731000.0 42829.0 34422.0 37618.0 31924.0 40328.0 36410.0 29917.0 32701.0 35406.0 31427.0 True False 42218.250606123314 34342.29797388138 34525.193249679265 34271.79745534213 37955.98632789858 34852.82917585549 31465.955874994743 34220.40784086971 31418.203438291188 36859.11507615474 1.145395121909358 0.9317179184287698 0.9366799278372975 0.9298052160105595 1.02975848035086 0.9455687990296551 0.8536818046223527 0.9284109987493409 0.8523862651986608 1.0 15.169733814311662 -7.001845930024052 24.17150475650367 0.9022213380365444 0.984680026140552 0.2374100543551404 0.0714617617861701 70.30038740230329 920568.8173168513 0.024877053446164477 0.021595290413966083 9.957586092561608e-08 7.001845930024052 0.08245868810400758 DKT(ph)PAPLQHLDTLLDGT(ph)Y(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 DKTPAPLQHLDTLLDGTYK 19 1 H7BZ69;A0A5F9ZGY2;A0A5F9ZHP5;A0A5F9ZH74;A0A5F9ZH37;A0A5F9ZHE7;A0A5F9ZH14;A0A5F9ZGX9;Q3SYG4-2;Q3SYG4-4;Q3SYG4-7;Q3SYG4-3;Q3SYG4 H7BZ69 BBS9 Protein PTHB1 3 DKT(0.998)PAPLQHLDT(0.165)LLDGT(0.921)Y(0.916)K 41.202 0.033512 2995200.0 11773.0 10084.0 11087.0 11942.0 14284.0 15275.0 15033.0 18585.0 15237.0 11604.0 True False 15516.56910638756 13343.45579663221 10939.979135882897 9188.956402060787 12300.913159787417 14319.851835282514 16370.90787722015 15713.115290813796 16042.396713047981 11197.747491982713 1.385686640772799 1.1916196365550988 0.976980338565022 0.8206075738571381 1.0985167479972682 1.2788153908216937 1.4619822324928546 1.403238937300914 1.4326449783346078 1.0 13.450920932459763 -6.83964480725346 3.7868770779791636 1.3587837855429181 1.077096921813595 0.2602519144402027 0.18215770098599973 0.27866955984811165 7.800821970723069 0.06906212855425282 0.06157810685834287 1.446622423876022e-07 6.83964480725346 -0.28168686372932306 DKVS(ph)PLQNLASINNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DKVSPLQNLASINNK 15 1 Q03112;Q03112-3;E7EUL6;A0A0C3SFZ7;Q03112-8;Q03112-5;Q03112-6;Q03112-1;Q03112-4 Q03112 MECOM MDS1 and EVI1 complex locus protein EVI1 1 DKVS(1)PLQNLASINNK 87.35600000000001 0.0024481 7836300.0 50118.0 63185.0 59779.0 56884.0 59852.0 46618.0 57061.0 48397.0 41553.0 43959.0 True False 58601.98752437901 69457.58922488254 61204.35807311999 53696.97390041624 48124.430251176986 44173.270013701236 51655.76899413496 47126.63003086018 42160.63401444734 51928.418720747475 1.1285147702940774 1.3375641110583532 1.1786293436404296 1.0340575589096872 0.9267455361961437 0.8506569447309639 0.9947495083938772 0.9075306198767653 0.8118990536024638 1.0 15.664236673943583 -5.887008420467611 2.1398722359175757 0.9112171143907976 1.2389049435140291 0.7786537517558058 0.07170096003747205 0.13133147189799574 1.223698977700813 0.021626375614729937 0.037159701707666935 1.297154120422294e-06 5.887008420467611 0.3276878291232316 DKVS(ph)PLQNLASINNKK ddPTM_PC-9_AZD4547_30min_R2 1 DKVSPLQNLASINNKK 16 2 Q03112;Q03112-3;E7EUL6;A0A0C3SFZ7;Q03112-8;Q03112-5;Q03112-6;Q03112-1;Q03112-4 Q03112 MECOM MDS1 and EVI1 complex locus protein EVI1 1 DKVS(1)PLQNLASINNKK 52.298 0.026343000000000002 8584900.0 33894.0 27869.0 37061.0 48475.0 42000.0 34495.0 30159.0 36600.0 40356.0 34581.0 True False 44671.58696100401 36877.1092420015 36569.54692477277 37299.837681284276 36169.0249727717 32338.022196927694 32843.0925742754 30944.31098433066 42489.13577159314 33370.32971563722 1.3386618394744556 1.1050867509025843 1.0958701108558841 1.1177545442053485 1.0838677735875957 0.9690651088105434 0.9842004215764533 0.9273001270296188 1.2732608917460853 1.0 15.026278320692539 -1.5228798718415701 0.7866707420853846 1.0383047004681416 66.52800869919712 0.454579057364204 0.09250018244468305 419.6978786582534 1.54959448324879 0.03316734210021708 48916.00308781586 0.029999922180007917 1.5228798718415701 65.48970399872897 DLAALLHDGIPVVS(ph)SS(ph)SGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLAALLHDGIPVVSSSSGK 19 0 F8VNZ0;C9JLV4;O14727-6;O14727-5;O14727-4;O14727 F8VNZ0 APAF1 Apoptotic protease-activating factor 1 2 DLAALLHDGIPVVS(0.5)S(0.5)S(0.5)S(0.5)GK 48.623000000000005 0.032307999999999996 8853100.0 13822.0 17644.0 22472.0 20438.0 20820.0 20259.0 26255.0 17156.0 15878.0 17755.0 True False 16161.79160305613 19395.579714866282 23007.81770553457 19292.92512089001 16740.47045762055 19196.582376068767 23767.936330260836 16705.673178284553 16110.185711775202 20973.84095149734 0.7705689978497872 0.9247509676324506 1.096976836943737 0.9198565568178714 0.7981595024170065 0.9152630851192903 1.1332181065559204 0.7965004224508493 0.7681085095014552 1.0 14.356303466747132 DLAEDAPWK ddPTM_PC-9_Lapatinib_30min_R1 2 DLAEDAPWK 9 0 Q60FE5;P21333-2;P21333;A0A087WWY3;F8WE98;O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;O75369-5;O75369-4;Q14315-2;Q14315 Q60FE5;O75369-2;Q14315-2 FLNA;FLNB;FLNC Filamin-A;Filamin-B;Filamin-C 0 ; 135.79 0.004784399999999999 9524500.0 79734.0 88568.0 89096.0 77419.0 81143.0 70034.0 93968.0 89271.0 74153.0 89979.0 False True 78596.97853857528 88362.92623760154 81770.8708005056 83112.65152221298 76370.32827327598 67038.80907722772 98833.2032510447 93418.85655980778 65801.10827429265 105531.75026051869 0.7447709181791123 0.8373112927575473 0.7748461538697472 0.7875606281241306 0.7236715783140715 0.6352477705688933 0.9365257660093975 0.8852203846633011 0.6235195390188655 1.0 16.687317587607403 -10.506185210014198 5.057719707947402 1.0000016057266394 0.7772472255623986 0.3445925298219603 0.0940578478772658 1.716737304005048e-06 3.4512875720904065e-07 0.09180408202687974 0.02226560017111474 3.117559780347907e-11 10.506185210014198 -0.22275438016424087 DLAFTLEER ddPTM_PC-9_Lapatinib_30min_R1 2 DLAFTLEER 9 0 P48163 P48163 ME1 NADP-dependent malic enzyme 0 ; 124.92 0.0066492 4115100.0 23017.0 22974.0 23313.4 19825.7 24546.0 20563.8 20435.0 25335.0 23944.0 21326.7 False True 22688.773359199167 22920.805114518356 21396.66224432648 21283.74811459642 23102.252539292767 19684.334210559096 21493.02431077707 26512.15658996465 21247.174578502076 25012.991678958504 0.9070795549132764 0.9163560044598686 0.8554219550764828 0.850907735778795 0.9236101317191461 0.7869644088642945 0.8592744357268343 1.0599354499552838 0.8494455541827762 1.0 14.610390000933773 -7.71572778955788 24.999964604901535 0.9660184371342097 0.8704654127349887 0.3508806288090315 0.06127135510846409 132.60692901251397 72523.39339873924 0.027601581060475194 0.01593570403177421 1.924297476998267e-08 7.71572778955788 -0.09555302439922098 DLAGAPPGEVVGCFT(ph)PQSR ddPTM_PC-9_AZD4547_30min_R2 2 DLAGAPPGEVVGCFTPQSR 19 0 Q9Y446;Q9Y446-2 Q9Y446 PKP3 Plakophilin-3 1 DLAGAPPGEVVGCFT(0.919)PQS(0.081)R;DLAGAPPGEVVGCFT(0.999)PQS(0.001)R 198.88 1.243e-14 36334000.0 35668.0 39589.0 56131.0 84217.0 62167.0 73006.0 65474.0 100893.0 65298.0 71460.0 True False 47009.68205951175 52385.37004491005 55386.6662646561 64802.071789679474 53536.185130530925 68440.92327899413 71301.05916005537 85302.30514049364 68749.51897149085 68958.20715073103 0.6817126488911828 0.7596683877004582 0.8031917962076678 0.9397296488296607 0.7763569753707464 0.9924985887378683 1.0339749553552526 1.23701454351963 0.9969737006244372 1.0 16.073434645734395 -6.626982089977405 0.825593310639074 1.0993430193142504 0.7432871215474522 0.6810190576975662 0.08897431163359362 0.35188742552038377 0.5299460851401766 0.05570528609895484 0.0611735647554232 2.3605755797783047e-07 6.626982089977405 -0.35605589776679814 DLAGAPPGEVVGCFT(ph)PQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DLAGAPPGEVVGCFTPQSR 19 0 Q9Y446;Q9Y446-2 Q9Y446 PKP3 Plakophilin-3 1 DLAGAPPGEVVGCFT(0.993)PQS(0.007)R;DLAGAPPGEVVGCFT(0.985)PQS(0.015)R;DLAGAPPGEVVGCFT(0.924)PQS(0.076)R 205.15 5.3478e-20 24630300.0 58441.0 61189.0 74759.0 74353.0 87024.0 63847.0 74774.0 74943.0 62945.0 57432.0 True False 68333.90703763578 67263.4395359868 76541.53808508629 70187.24246567856 69972.27190701116 60498.75092378014 67690.86540312022 72975.82565867214 63865.45154475938 67843.9669685381 1.0072215716590525 0.9914431974058873 1.1281996248919466 1.0345391875187242 1.0313705850876917 0.8917336887425198 0.9977433282241754 1.0756420787203362 0.9413578597839996 1.0 16.04993290909845 -6.548987231897373 24.99978829297844 0.9842178043881339 1.0418602721621515 0.21245729394741542 0.05516385142379369 381.0873145068925 364901.3415963119 0.01880747350820852 0.01880793434375425 2.824963026598692e-07 6.548987231897373 0.0576424677740176 DLAGAPPGEVVGCFT(ph)PQSR ddPTM_PC-9_Lapatinib_30min_R1 2 DLAGAPPGEVVGCFTPQSR 19 0 Q9Y446;Q9Y446-2 Q9Y446 PKP3 Plakophilin-3 1 DLAGAPPGEVVGCFT(0.989)PQS(0.011)R;DLAGAPPGEVVGCFT(0.68)PQS(0.32)R 203.23 6.67e-20 32678000.0 58261.0 64455.0 78601.0 70026.0 53627.0 50866.0 46163.0 44360.0 58543.0 33994.0 True False 57430.18745624112 64305.75840760341 72138.72918863414 75175.94563988825 50472.76529473854 48690.57975443738 48553.09426270625 46421.12754414182 51949.27085487999 39869.81760584222 1.4404426933677705 1.6128932177051278 1.809356890011543 1.8855352282542808 1.2659392072900442 1.2212390895739296 1.2177907293860217 1.164317529692928 1.3029723729477947 1.0 15.283009384941156 -6.36780665366171 5.802690124111651 1.1999231240574797 1.6889398828245479 0.7692423797363815 0.13223186486422725 0.11665540716568078 5.371904178924575 0.04321399807029515 0.04907287266101144 4.287393511297986e-07 6.36780665366171 0.4890167587670682 DLAGAPPGEVVGCFTPQS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 DLAGAPPGEVVGCFTPQSR 19 0 Q9Y446;Q9Y446-2 Q9Y446 PKP3 Plakophilin-3 1 DLAGAPPGEVVGCFT(0.318)PQS(0.682)R 80.459 0.022295 0.0 4600.5 3817.9 6103.5 5717.7 4988.1 6646.3 4374.0 6721.5 4497.8 6526.1 True False 6063.363303655481 5051.961511896283 6022.563602043946 4399.572602584402 4295.588415873393 6230.705810333109 4763.277526439225 5682.846619704331 4735.544525559309 6297.623225390239 0.9628018518493948 0.8022012958044553 0.9563232645869746 0.6986084186247548 0.682096762879493 0.9893741793273155 0.7563611470491017 0.9023795829500719 0.7519574220424826 1.0 12.620591731065053 -9.93753912986598 24.828938261014454 0.999999999999989 0.8321663654871853 0.17734498208999927 0.10749938626756919 0.0 0.0 0.10076429742292288 0.024438931856815563 1.1546779436974709e-10 9.93753912986598 -0.16783363451280375 DLAGS(ph)IIGK ddPTM_PC-9_AZD4547_30min_R2 1 DLAGSIIGK 9 0 P61978;P61978-2;P61978-3;S4R359 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 DLAGS(1)IIGK 78.488 0.021529 2541500.0 36287.0 42141.0 40660.0 61853.0 57889.0 53786.0 34162.0 50777.0 39690.0 38376.0 True False 47825.51118351191 55762.25413783005 40120.821833227965 47593.74646932385 49852.11158687574 50422.75291734897 37202.35181943687 42930.58138938132 41787.93237125906 37032.467920745315 1.2914481229245975 1.505766622337164 1.0833958438603704 1.2851897035644817 1.3461730850227498 1.3615823019211342 1.004587431198351 1.159268712019377 1.1284133820271203 1.0 15.176503076463254 -7.256581690559189 24.943408436936437 1.0863397716823393 1.3109632902351143 0.5411771719624949 0.10761470724830731 340.7081822932614 1749483.6959794958 0.04248730463475869 0.03184517290948907 5.538833489784276e-08 7.256581690559189 0.22462351855277496 DLAGS(ph)IIGK ddPTM_PC-9_Lapatinib_30min_R1 1 DLAGSIIGK 9 0 P61978;P61978-2;P61978-3;S4R359 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 DLAGS(1)IIGK 81.017 0.017845 2653200.0 69743.0 64560.0 66227.0 50826.0 60872.0 67625.0 69013.0 70098.0 66001.0 65292.0 True False 68748.4520307003 64410.51528655459 60782.0717036129 54563.91359056563 57291.62863895664 64732.83639157452 72586.15545679766 73355.00898533045 58567.27235865834 76577.63520387861 0.8977614919508278 0.8411139246474437 0.7937313752479827 0.7125306683249732 0.7481509253507851 0.8453230008896363 0.9478766909365361 0.957916874685823 0.7648091012830328 1.0 16.224635488519 -7.033491577244267 5.231132546638945 0.9128815840515843 0.7957216041475533 0.364968789719917 0.07381187816512452 0.2300086719999917 16.68689534776266 0.029081765772718347 0.023216010866052263 9.257813396535152e-08 7.033491577244267 -0.11715997990403093 DLAGSIIGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLAGSIIGK 9 0 P61978;P61978-2;P61978-3;S4R359 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 94.85 0.025870999999999998 4221800.0 22836.0 24056.0 26342.0 29760.0 34941.0 29228.0 30422.0 28058.0 24487.0 23763.0 False True 26701.68376844087 26444.12069943456 26970.093182591325 28092.643683221802 28094.561876067208 27695.23222704663 27540.207923793372 27321.507229908355 24845.076050147312 28071.043792195494 0.9512180582278403 0.9420426577363944 0.9607798478120624 1.0007694723141116 1.0008378058203256 0.9866121271467165 0.9810895571845565 0.9732985859793525 0.8850784542986931 1.0 14.77679508949275 -5.526137403315412 24.9548327301194 0.9764017479232068 0.9478255773875572 0.11517912732377533 0.032044557223663145 195.6371161664191 1498179.9574412429 0.008946665691559646 0.015604799090511745 2.9775742270407574e-06 5.526137403315412 -0.028576170535649537 DLASVQALLR ddPTM_PC-9_Lapatinib_30min_R1 1 DLASVQALLR 10 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 95.523 0.027110000000000002 1090700.0 8073.5 10372.0 11327.0 9962.3 10843.0 9578.3 8880.6 8513.7 7682.5 8010.8 False True 7958.370409501432 10347.984271253774 10395.737783484426 10694.96077525858 10205.236058158207 9168.65843710784 9340.394014890479 8909.2775827899 6817.215949688532 9395.456106279958 0.8470446053366187 1.1013817907506525 1.1064644085278494 1.1383120366141701 1.0861884662881867 0.975860919724746 0.9941394977777953 0.9482538667638397 0.7255864827181598 1.0 13.197747484231417 -7.598604368781262 1.5182328152411781 0.8669169039069035 1.0584979265396197 0.31660909014987426 0.10110305221648026 0.4524900780317706 1.9977152982103268 0.07232746790603684 0.03226172911295826 2.5199715123519717e-08 7.598604368781262 0.19158102263271626 DLAVPAALT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 DLAVPAALTPR 11 0 Q8TEM1 Q8TEM1 NUP210 Nuclear pore membrane glycoprotein 210 1 DLAVPAALT(1)PR;DLAVPAALT(1)PR 132.06 0.0003116 35181000.0 137357.0 137978.0 210429.0 139976.0 127633.0 98506.0 171325.0 184800.0 144130.0 115018.0 True False 181033.66879691498 182576.69019314967 207638.57396813403 107706.69580764194 109913.36105594704 92346.40424787842 186572.5930994967 156243.40628153822 151748.4175527733 110991.25482875465 1.6310624569136265 1.6449646458618943 1.8707651723416756 0.9704070466976847 0.9902884801647601 0.8320151384030854 1.6809666075706091 1.4077091616145962 1.3672105769675433 1.0 16.760086483334575 -5.757273693723914 24.999999544863453 1.194032092592321 1.7085341945228596 0.4978897513879843 0.24684823738240563 101.319635358783 608050.5716005163 0.07446579052186451 0.12328692131347034 1.7487442772446935e-06 5.757273693723914 0.5145021019305387 DLAVPAALT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DLAVPAALTPR 11 0 Q8TEM1 Q8TEM1 NUP210 Nuclear pore membrane glycoprotein 210 1 DLAVPAALT(1)PR;DLAVPAALT(1)PR;DLAVPAALT(1)PR;DLAVPAALT(1)PR 102.87 0.007675700000000001 30189500.0 173049.0 195247.0 173462.0 118717.0 214314.0 106807.6 135849.0 99882.3 103689.0 116999.0 True False 202342.77782645464 214629.83181752963 177597.99193829842 112065.67137570726 172320.71016592204 101206.42143196627 122980.39925841198 97260.49545904482 105205.25546468423 138209.99253642547 1.4640242294574095 1.5529255727364546 1.2849866256341211 0.8108362450433688 1.2468035559766537 0.7322655878538822 0.8898083054740076 0.7037153658293676 0.761198619100983 1.0 17.076502400304747 -5.575684143846444 0.8888611243467895 0.8206969189496576 1.6361017143388368 0.7144673295926379 0.16098564090453923 0.45333695718185213 0.5839496751838504 0.06440811506033378 0.2870101981367418 2.6565369208018154e-06 5.575684143846444 0.8154047953891792 DLAVPAALT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 DLAVPAALTPR 11 0 Q8TEM1 Q8TEM1 NUP210 Nuclear pore membrane glycoprotein 210 1 DLAVPAALT(1)PR;DLAVPAALT(1)PR 126.5 0.00099663 30199000.0 235034.0 266317.0 124276.0 79659.0 97666.0 103093.0 105480.0 78191.0 168413.0 35476.0 True False 231682.37206004353 265700.35934896773 114058.50699923305 85517.3885946341 91921.47789874375 98683.95271152075 110941.23828239618 81824.03931027948 149444.55447248885 41607.97933120136 5.568219744963859 6.385803002688045 2.7412652292321695 2.0553122254246454 2.209227157297035 2.3717554732949684 2.666345255540987 1.9665468168727085 3.5917282423859995 1.0 15.344572605936406 -5.305716413719097 5.388315001704039 2.340060950298404 5.986710586220947 0.8378136964256719 0.643568997956002 0.060464750955917565 4.414258196688224 0.1568514418688232 0.34731061963924037 4.946335681481852e-06 5.305716413719097 3.6466496359225427 DLDAPDDVDFF ddPTM_PC-9_AZD4547_30min_R2 1 DLDAPDDVDFF 11 0 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;H7C3A1 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 0 96.25299999999999 0.021559000000000002 0.0 4514.3 4927.1 6532.3 6717.1 7505.0 6797.9 4638.2 7327.8 5655.0 5304.1 False True 5949.753496726865 6519.688720308072 6445.677433871003 5168.576373160485 6463.060295729803 6372.826238367728 5050.99081461601 6195.4568860923 5953.9117550886895 5118.405073442392 1.1624233352686462 1.2737734952117115 1.2593136614597702 1.0098021354305102 1.2627098095975944 1.2450804785721412 0.9868290497021873 1.2104272321544756 1.163235748178949 1.0 12.321478612250692 -14.52287873901633 0.11929391765985176 0.43011187508581383 1.2613460446999223 0.2542241895841757 0.09508544578122435 224.77838244788043 1.7351179570910646 30.922246386016937 0.9427135306030627 3.0000000432702357e-15 14.52287873901633 0.8312341696141085 DLDDFQSWLSR ddPTM_PC-9_Lapatinib_30min_R1 2 DLDDFQSWLSR 11 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 ; 144.55 0.00080611 8235400.0 35293.0 31502.0 28826.0 25384.0 27929.0 29230.0 27711.0 23523.0 30971.0 26225.0 False True 34789.71534805646 31429.059054477104 26456.03755157783 27250.824038541658 26286.27113052665 27979.901038458003 29145.739989035657 24615.964454933448 27482.71984091162 30757.956307384015 1.1310801992297697 1.0218188341379488 0.8601363916115119 0.885976420741569 0.8546169604973444 0.9096801087444458 0.9475837632957 0.8003120951512611 0.8935157968968792 1.0 14.908672027089985 -5.01803444468432 2.8316245448732005 0.8876968313364078 1.1304078408715967 0.6840725084574719 0.05186196161355427 0.15189651397852819 2.248314479446326 0.013131948377122029 0.06619903246725757 9.593245427263649e-06 5.01803444468432 0.24271100953518898 DLDEDELLGNLS(ph)ETELK ddPTM_PC-9_AZD4547_30min_R2 1 DLDEDELLGNLSETELK 17 0 Q9NYL9;H0YNU8 Q9NYL9 TMOD3 Tropomodulin-3 1 DLDEDELLGNLS(0.5)ET(0.5)ELK 105.02 0.005306100000000001 0.0 2571.4 2062.1 3320.9 2679.8 2570.6 3750.8 3756.5 3744.7 3253.0 2796.9 True False 3389.051711557376 2728.6334984366595 3276.8626961624864 2062.0135124972785 2213.71656178588 3516.2618830623674 4090.8212226952355 3166.042659645437 3424.9469388688767 2698.981382310103 1.2556780620163561 1.0109864100289483 1.214110892961316 0.7639969382568941 0.8202044579837461 1.3028107218926943 1.5156907896837115 1.1730509444772712 1.2689776081142907 1.0 11.398199309728605 -6.786663106561566 24.906852734322648 1.2793958774156335 1.0102235579166874 0.2877908055397306 0.1855847025411922 267.50073134814926 264138.2179526033 0.0671878359934459 0.05927675887614523 1.6343192399102015e-07 6.786663106561566 -0.26917231949894616 DLDEDELLGNLS(ph)ETELK ddPTM_PC-9_Lapatinib_30min_R1 2 DLDEDELLGNLSETELK 17 0 Q9NYL9;H0YNU8 Q9NYL9 TMOD3 Tropomodulin-3 1 DLDEDELLGNLS(0.955)ET(0.045)ELK;DLDEDELLGNLS(0.963)ET(0.037)ELK 143.57 2.4644e-08 0.0 3749.65 7656.8 4065.05 7551.4 8030.5 7012.1 8096.5 8099.299999999999 7143.7 8037.4 True False 3696.1793033984077 7639.071150032391 3730.837280546781 8106.755146731944 7558.161778570458 6712.208829003471 8515.69715352124 8475.623045948325 6339.101279504061 9426.653880837692 0.3920987606123871 0.8103693258072133 0.39577535440552775 0.8599822640365729 0.8017862832467557 0.7120457496214972 0.903363723879984 0.8991125751606726 0.6724656871501409 1.0 13.202530042179506 -4.125037794256417 0.29221874286401295 0.9120028102316996 4.207427060771905e-18 0.4336648432779131 0.14812421848523255 12.048063048625723 0.6262889207824344 0.1625803976202337 4.2004833841446025 7.498289530097554e-05 4.125037794256417 -0.9120028102316996 DLDEDELLGNLSET(ph)ELK ddPTM_PC-9_AZD4547_30min_R2 1 DLDEDELLGNLSETELK 17 0 Q9NYL9;H0YNU8 Q9NYL9 TMOD3 Tropomodulin-3 1 DLDEDELLGNLS(0.216)ET(0.784)ELK 158.98 1.7512e-17 0.0 3623.2 3142.5 2546.8 2403.5 2899.4 3479.6 3008.5 3515.7 3060.3 3079.2 True False 4775.302232758298 4158.25167006314 2513.0277679504406 1849.4102087048316 2496.868357287008 3262.0200619344714 3276.2506717632405 2972.4293477489396 3222.061210273725 2971.398145235536 1.607089322720086 1.3994259492726193 0.8457391588467988 0.6224040395496151 0.840300839956635 1.0978064542326416 1.1025956508105512 1.00034704286097 1.0843586260697216 1.0 11.536926213185241 -5.120637373510929 3.9349604142442316 0.9454281682115759 1.5670930654396331 0.7130681048011445 0.14284943818762547 0.13374153255576732 3.4992402103232476 0.0427588214609946 0.1351409058514511 7.574650980025861e-06 5.120637373510929 0.6216648972280572 DLDEEGS(ph)EK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLDEEGSEK 9 0 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 DLDEEGS(1)EK 89.40299999999999 0.0093723 18607000.0 37966.0 109780.0 34252.0 24207.0 29371.0 20396.0 42919.0 10927.0 22071.0 28054.0 True False 44392.89393731939 120678.23288925526 35068.69758143336 22850.760270152892 23615.96339148767 19326.397854894047 38853.40161334852 10640.177828113501 22393.74662077027 33139.96812465819 1.3395575327753055 3.641471000675561 1.0581994964364516 0.6895226991226497 0.7126127370628317 0.5831749077789248 1.1724031075467203 0.3210678353126281 0.6757322920931821 1.0 15.016284594467907 -5.432285510762658 7.014616208397495 0.7299515659137759 2.482105398919095 0.6057224554421433 0.5581776433337814 0.14484602379408262 9.631705963031635 0.13354638752512932 0.27958523851732814 3.695851298922781e-06 5.432285510762658 1.752153833005319 DLDEEGS(ph)EK ddPTM_PC-9_Lapatinib_30min_R1 2 DLDEEGSEK 9 0 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 DLDEEGS(1)EK;DLDEEGS(1)EK 108.9 0.0024045000000000004 64479000.0 67723.0 104048.0 60101.0 78239.0 95151.0 73076.0 100775.0 115617.0 72877.0 104573.0 True False 66757.25760112287 103807.08324869006 55159.72777656906 83992.9570576529 89554.4052540636 69950.70982847615 105992.63640413804 120988.98790060946 64668.82483116829 122648.3037152362 0.544298254267905 0.8463800974346003 0.4497390188505049 0.6848277107253521 0.7301723916377211 0.5703357299656351 0.864199774423549 0.9864709436301758 0.5272704380919595 1.0 16.904167755307135 -7.271223909928343 24.655710944140598 0.8433578826995889 0.6449263106031266 0.2916889822028188 0.1576687201226962 774.8899358381109 1952610.6140665624 0.06216079644361615 0.04250459046161843 5.3552048713843016e-08 7.271223909928343 -0.19843157209646234 DLDEEGS(ph)EKELHENVLDK ddPTM_PC-9_Lapatinib_30min_R1 1 DLDEEGSEKELHENVLDK 18 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 DLDEEGS(1)EKELHENVLDK 69.805 0.0050184 13009000.0 18847.0 35055.0 16252.0 17653.0 21659.0 22242.0 30680.0 32588.0 17304.0 25917.0 True False 18578.238323883492 34973.8323012728 14915.823294534213 18951.260508681702 20385.060203232377 21290.76150863437 32268.46028160707 34102.15744834296 15355.041300801859 30396.718917768252 0.6111922268368141 1.1505791923097666 0.49070504401760423 0.6234640179405625 0.6706335726030085 0.7004295945964404 1.0615770856355389 1.1219025823345923 0.505154564291679 1.0 14.891627984253427 -7.23975177900599 23.801860017299198 0.9323171049883343 0.7125632731843118 0.17965581904930739 0.22380767159313752 763.7503916247433 838206.6023066924 0.08525717326252477 0.0659657146673538 5.757689240178614e-08 7.23975177900599 -0.21975383180402253 DLDENEVERPEEENASANPPS(ph)GIEDETAENGVPKPK ddPTM_PC-9_Lapatinib_30min_R1 1 DLDENEVERPEEENASANPPSGIEDETAENGVPKPK 36 2 Q6UN15;A0A0B4J203 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 DLDENEVERPEEENAS(0.15)ANPPS(0.425)GIEDET(0.425)AENGVPKPK 40.492 0.015553999999999998 3771300.0 10534.0 10830.0 11593.0 9500.6 12091.0 10879.0 9467.7 10100.0 7154.5 8670.5 True False 10383.783228300996 10804.92380039322 10639.86829027412 10199.305817072527 11379.83115182061 10413.730530187639 9957.891180188122 10569.28287186276 6348.684869775022 10169.184372284972 1.0211028582194743 1.062516265300577 1.0462853165758257 1.0029620315341758 1.1190505290507986 1.024047765184507 0.9792222085506969 1.039344207453669 0.624306201692801 1.0 13.311916350854244 -8.219426285899743 24.24957774361935 0.8121530950415765 1.0372559921402669 0.49324951728905597 0.09108601265586184 218.72000599046353 126243.50891715298 0.055817482880138526 0.02109647699919769 6.033561086713657e-09 8.219426285899743 0.22510289709869036 DLDIIDNYDYSHTVK ddPTM_PC-9_AZD4547_30min_R2 2 DLDIIDNYDYSHTVK 15 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 137.17 3.2728e-05 14660100.0 85859.0 81834.0 109363.0 117459.0 123197.0 118243.0 94549.0 116555.0 101942.0 112172.0 False True 113160.37602185778 108285.24014890929 107912.77516348516 90380.64227345979 106093.22308501347 110849.24651779435 102963.67783431712 98544.10291744953 107330.4460012822 108244.89242249975 1.0454107670981094 1.0003727448520348 0.996931797412498 0.8349644981001736 0.9801222091007498 1.024059833558976 0.9512104962184351 0.9103810878467481 0.9915520594020427 1.0 16.72393942686618 -5.53668765562341 24.99999347946189 0.9528669463391164 1.0168319385114761 0.219827614649158 0.05130864747592993 336.0800008536363 608445.579386449 0.014273069307568578 0.02473665290806073 2.906111977351193e-06 5.53668765562341 0.06396499217235974 DLDIIDNYDYSHTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DLDIIDNYDYSHTVK 15 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 115.38 0.00013499 10696100.0 118789.0 115682.0 129283.0 140555.0 153894.0 136884.0 147743.0 125002.0 127043.0 109412.0 False True 138897.63151030475 127166.1444442959 132365.5970285075 132680.15903545832 123739.57543732245 129705.5620694899 133747.71347330877 121720.82995056688 128900.7635332569 129247.5294950845 1.074663725124334 0.9838961328009929 1.024124774729575 1.0265585698526205 0.9573844538516186 1.003543840073344 1.0348183365345907 0.9417652347095434 0.997317039921906 1.0 16.979777178812583 -4.755647493936104 24.999701466203142 0.9967631345008232 1.074663850472232 0.41029054522376796 0.02807560964201959 194.4846834410617 839375.3347635488 0.007022290114336131 0.06078070492705612 1.7553046610619315e-05 4.755647493936104 0.07790071597140868 DLDIIDNYDYSHTVK ddPTM_PC-9_Lapatinib_30min_R1 2 DLDIIDNYDYSHTVK 15 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 147.51 4.7808999999999996e-05 23661000.0 139182.0 129680.0 154241.0 133157.0 140927.0 135116.0 141150.0 132222.0 138844.0 124934.0 False True 137197.23915714739 129379.73392751516 141559.90036747753 142949.8099787301 132637.95093314242 129337.40365077984 148458.05634774576 138365.51682014222 123205.9266278626 146528.67543590942 0.9363166543954494 0.8829652867783202 0.9660900840490761 0.9755756649916304 0.9052013234853631 0.8826763994556894 1.0131672582591538 0.9442896853364534 0.8408315045593379 1.0 17.16082349990962 -10.623828842304324 4.322328465778125 1.000008574737709 0.9297443319457598 0.16606768263601968 0.0485254486136136 9850144.016303241 24210618.369251072 437.674957831766 0.011797140918554027 2.3777771962513723e-11 10.623828842304324 -0.0702642427919492 DLDLLASVPS(ph)PSSSGSR ddPTM_PC-9_AZD4547_30min_R2 2 DLDLLASVPSPSSSGSR 17 0 A0A087WV97;Q8WU79-3;Q8WU79-2;Q8WU79 A0A087WV97 SMAP2 Stromal membrane-associated protein 2 1 DLDLLAS(0.002)VPS(0.956)PS(0.037)S(0.003)S(0.001)GSR;DLDLLASVPS(0.981)PS(0.017)S(0.001)SGSR 135.69 4.272e-05 28039000.0 47413.0 54046.0 68395.0 75670.0 84762.0 74127.0 62860.0 93130.0 68927.0 83835.0 True False 62489.34774833546 71515.31257286629 67488.0376115009 58225.45058984584 72994.25939862076 69491.82697178326 68454.41822404432 78738.89841450016 72570.34050274066 80899.96216738822 0.7724274038477325 0.8839968605287556 0.8342159353778557 0.7197216046822484 0.9022780412132956 0.8589846658765964 0.8461613131833966 0.9732872093510173 0.8970380029670108 1.0 16.30385140753308 -7.808282864736015 0.5958437280008191 0.9931791133720452 0.8122460614415021 0.5410324104377628 0.054026842901322744 0.6034076204057865 0.4563409221909682 0.05209662132575157 0.02908565865207954 1.5549525298388053e-08 7.808282864736015 -0.1809330519305431 DLDLLASVPS(ph)PSSSGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DLDLLASVPSPSSSGSR 17 0 A0A087WV97;Q8WU79-3;Q8WU79-2;Q8WU79 A0A087WV97 SMAP2 Stromal membrane-associated protein 2 1 DLDLLAS(0.003)VPS(0.966)PS(0.026)S(0.003)S(0.001)GS(0.001)R;DLDLLASVPS(0.999)PS(0.001)SSGSR;DLDLLASVPS(0.95)PS(0.049)S(0.001)SGSR;DLDLLAS(0.008)VPS(0.982)PS(0.011)SSGSR;DLDLLAS(0.008)VPS(0.906)PS(0.067)S(0.013)S(0.005)GS(0.001)R;DLDLLAS(0.015)VPS(0.806)PS(0.033)S(0.049)S(0.015)GS(0.082)R 186.96 2.5611999999999998e-08 30067700.0 87337.3 107625.0 125598.0 116444.0 150729.0 125681.0 145306.0 117643.0 120813.0 108149.3 True False 102121.7798996959 118309.29873115392 128592.73265306742 109920.0201965417 121194.73446717976 119090.06711124418 131541.56375566128 114554.9959030621 122579.66156925906 127755.91198061247 0.799350717446198 0.926057329926993 1.006550152235475 0.8603908695295648 0.9486428658234745 0.9321687369686393 1.0296319106987653 0.8966708008036945 0.9594832808039527 1.0 16.963030528713304 -4.779607454253145 4.116971190906669 0.9498301060998443 0.7866270609597351 0.4757140670478217 0.04835696563852903 0.1881388126398047 6.211452912711999 0.011669368080726408 0.09079176981464801 1.6610876363604795e-05 4.779607454253145 -0.1632030451401092 DLDLLASVPS(ph)PSSSGSR ddPTM_PC-9_Lapatinib_30min_R1 2 DLDLLASVPSPSSSGSR 17 0 A0A087WV97;Q8WU79-3;Q8WU79-2;Q8WU79 A0A087WV97 SMAP2 Stromal membrane-associated protein 2 1 DLDLLAS(0.001)VPS(0.994)PS(0.005)SSGSR;DLDLLASVPS(0.999)PS(0.001)SSGSR 199.61 1.7913e-12 19639400.0 65691.0 67980.0 77280.0 69713.0 83277.0 71107.0 72429.0 67606.0 72518.0 53684.0 True False 64754.23429374598 67822.5964866786 70926.33670942692 74839.9265757507 78378.81058888136 68065.9193685129 76179.01922218129 70747.22156783697 64350.25919160599 62963.20787056641 1.0284456031347924 1.0771782248785933 1.1264727307927247 1.1886295045449284 1.244835090835982 1.0810427497346726 1.2098973638506896 1.1236279719621682 1.0220295529397254 1.0 15.942221425176648 -11.148105672721636 4.745161800943029 0.9978646681061881 1.128181176900667 0.20889036622237134 0.07071209655990694 0.0016899258840311145 0.00013347020137788516 0.07243278215474988 0.017289001264218867 7.110404819247539e-12 11.148105672721636 0.13031650879447898 DLDQCRDGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLDQCRDGK 9 1 P60903 P60903 S100A10 Protein S100-A10 0 79.986 0.025079 6992200.0 35461.0 7088.9 18486.0 49662.0 48879.0 85521.0 35895.0 101990.0 81140.0 43344.0 False True 41463.846913324625 7792.639143092019 18926.776348545398 46879.599146376364 39301.510830837404 81036.12820888383 32494.765742704738 99312.8705673374 82326.51899820114 51201.924089084765 0.8098103274631411 0.15219426382363735 0.36964970917138273 0.9155827633510781 0.7675787879076151 1.5826774022767462 0.6346395437438644 1.939631612174296 1.6078794002929182 1.0 15.643910405040812 -6.428938803730335 0.990143949784286 1.4284142616250477 0.40563795896629 0.48327759070015197 0.38936690733383256 0.43510250022461955 0.9157305784986629 0.19001109692893126 0.2465183406969631 3.724441835249356e-07 6.428938803730335 -1.0227763026587577 DLDRPESQS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 DLDRPESQSPK 11 1 Q8WUA4;A0A087WZD8;Q8WUA4-2 Q8WUA4 GTF3C2 General transcription factor 3C polypeptide 2 1 DLDRPES(0.373)QS(0.627)PK 103.97 0.013226 12203000.0 10250.0 14445.0 11670.0 11131.0 10619.0 13131.0 11955.0 12946.0 11413.0 12157.0 True False 13509.286786755503 19114.06376262915 11515.248174957458 8564.919922235687 9144.735147282443 12309.916494212423 13018.971840096237 10945.493169484818 12016.267879898716 11731.387130302812 1.1515506765487502 1.6293097781469066 0.9815760103264298 0.730085865132865 0.7795101334317998 1.0493146596803746 1.1097555383256874 0.933009289345845 1.0242836372571869 1.0 13.51808598862704 -5.357300497141931 7.333251399525794 0.9417369270328703 1.3883280477435394 0.5670889656647868 0.1536413958172589 0.17142312206342533 11.342983736576018 0.04111915317450897 0.08624122239176366 4.392375928898083e-06 5.357300497141931 0.4465911207106691 DLDTGEEVTR ddPTM_PC-9_Lapatinib_30min_R1 1 DLDTGEEVTR 10 0 Q14166 Q14166 TTLL12 Tubulin--tyrosine ligase-like protein 12 0 106.88 0.010378 2329800.0 18012.0 23936.0 24060.0 18680.0 29095.0 25590.0 20653.0 20963.0 24741.0 20005.0 False True 17755.14557700375 23880.577662623466 22081.879674285818 20053.78951465327 27383.689302970877 24495.575353203567 21722.3112840949 21937.01750919396 21954.40804572001 23462.83759501305 0.756734794123007 1.0178043284798257 0.9411427575571357 0.8547043567703694 1.1671090162083035 1.0440158933892132 0.9258177403363993 0.9349686464972422 0.9357098414382048 1.0 14.518089882970957 -4.755321780981939 24.9582761105887 0.979111758852242 0.7567344208701173 0.40830783917028635 0.08067242554923895 216.14589890394308 881733.9454353751 0.021043716827781833 0.18869972879124108 1.7566216013775437e-05 4.755321780981939 -0.22237733798212467 DLEAEHVEVEDTTLNR ddPTM_PC-9_AZD4547_30min_R2 2 DLEAEHVEVEDTTLNR 16 0 H3BV85;H3BTW0;A0A0B4J295;A0A087WZT3;H3BVE0;Q9H3K6-2;Q9H3K6 H3BV85 BOLA2B;BOLA2 BolA-like protein 2 0 ; 182.02 1.4609999999999999e-06 11777400.0 47904.0 53469.0 62463.0 82810.0 75533.0 60470.0 52610.0 74242.0 55114.0 62230.0 False True 63136.47553490101 70751.80860671648 61634.699807400815 63719.433901746226 65046.54674448485 56688.801340722355 57292.1880809254 62769.60481143926 58027.213522539 60051.346641337834 1.051374849459903 1.1781885430361476 1.026366655447707 1.0610825146406189 1.083182149652385 0.9440054971506536 0.9540533441008116 1.0452655655890029 0.9662932934562125 1.0 15.873908978036502 -6.747525155781834 24.87765937304011 0.983010753892094 1.08145679742016 0.5396229217420336 0.04529755210088321 178.24429929111804 318687.8031685822 0.015138072620048878 0.015063270932659379 1.7884419335983193e-07 6.747525155781834 0.09844604352806607 DLEAEHVEVEDTTLNR ddPTM_PC-9_Lapatinib_30min_R1 2 DLEAEHVEVEDTTLNR 16 0 H3BV85;H3BTW0;A0A0B4J295;A0A087WZT3;H3BVE0;Q9H3K6-2;Q9H3K6 H3BV85 BOLA2B;BOLA2 BolA-like protein 2 0 ; 125.22 2.7317e-05 12467200.0 74753.0 67682.0 75859.0 62779.0 83468.0 74658.0 70896.0 69133.0 77456.0 59797.0 False True 73687.00851197887 67525.28648736971 69622.16584420821 67395.97708460482 78558.57634440194 71465.05137629823 74566.64798320782 72345.1715624245 68732.08963216074 70132.83177550594 1.0506777873713953 0.962819905854038 0.9927185895910725 0.9609761274197263 1.120139802651441 1.0189956624745555 1.0632202649665488 1.0315449944185944 0.9800272980873074 1.0 16.097802360889915 -4.446775327696786 22.317297001938417 1.017424142875333 2.711275428777939 0.0490866150985102 0.046184575294993056 1977.1910333905969 537647.7974736359 0.011478066532237251 12269.497730158384 3.574577128880695e-05 4.446775327696786 1.693851285902606 DLEALLNSK ddPTM_PC-9_Lapatinib_30min_R1 2 DLEALLNSK 9 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ; 138.66 0.0040344000000000005 7195300.0 62903.0 66086.0 71514.0 65342.0 68756.0 61562.0 73138.0 64156.0 59365.0 67933.0 False True 62005.99168500257 65932.98192731189 65634.39497202297 70147.46865452216 64711.90725949706 58929.136768031196 76924.7277730175 67136.92197299279 52678.688558836286 79675.12853496756 0.7782352262888359 0.8275227557163644 0.823775200352737 0.8804186443669942 0.8121970864608835 0.7396177182465237 0.9654798076573798 0.8426333688753066 0.6611685418959423 1.0 16.281841820965326 -10.709590877193541 4.646945351781147 1.0000298970339978 0.8201408715068436 0.34238178037794176 0.07675011132219907 2.351855152429817e-05 4.116174296903161e-06 0.07351897052895506 0.01782800804758497 1.9516822969680385e-11 10.709590877193541 -0.17988902552715424 DLEALMFDR ddPTM_PC-9_Lapatinib_30min_R1 1 DLEALMFDR 9 0 A0A3B3ITK7;P36871;P36871-2;P36871-3 A0A3B3ITK7 PGM1 Phosphoglucomutase-1 0 103.56 0.012972999999999998 862830.0 6949.7 4972.3 6284.2 5565.3 7168.2 6665.2 5702.3 5019.5 6113.7 6491.2 False True 6850.596003581108 4960.786944847198 5767.537333713504 5974.590727296564 6746.580569223431 6380.144933340069 5997.537192431813 5252.724294585661 5425.110725884902 7613.195271019682 0.8998319049635469 0.6516037968618621 0.7575711811396928 0.7847678293553543 0.8861693847397953 0.8380377366158818 0.7877818680498032 0.6899500285485428 0.7125931402989332 1.0 12.894286367056903 -10.575258714000533 4.047875787514756 1.0000315779369127 0.7770824248246887 0.4285864540714537 0.07663745194781353 112977890.67231439 215801039.48528105 49549.75574934255 0.019899061081740787 2.659140508624256e-11 10.575258714000533 -0.22294915311222396 DLEDSLAR ddPTM_PC-9_AZD4547_30min_R2 3 DLEDSLAR 8 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ;; 122.18 0.015388999999999998 19562800.0 98398.0 101939.0 127657.0 145335.0 136197.0 134269.0 123041.0 150548.0 119741.0 114196.0 False True 129686.51719445508 134888.78822420575 125964.18477039794 111830.26115336665 117288.39748134719 125873.13820435689 133991.41063799933 127284.2658488802 126070.26480390341 110198.03279855741 1.1768496578475474 1.2240580416783227 1.1430710836795166 1.014811773979604 1.0643420259211978 1.142244875046487 1.215914724021765 1.1550502546770187 1.1440337145977961 1.0 16.749738944288737 -5.512667711161093 24.59443156805243 1.1132548830711797 1.1962315513333364 0.25690775531377674 0.06335124731071835 607.8313116783086 1464028.0673755754 0.01826092651529673 0.03431813335791098 3.0713710672585806e-06 5.512667711161093 0.08297666826215666 DLEDSLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DLEDSLAR 8 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ;; 131.03 0.015985 15022000.0 106082.0 143711.0 133481.0 128402.0 135351.0 110774.0 130837.0 96922.0 106663.0 92791.0 False True 124039.58738499477 157977.67832708836 136663.69326951174 121208.05222490052 108829.94317528312 104964.8164335179 118443.17218214946 94377.90019734774 108222.74458842917 109613.27376684794 1.1316110095282093 1.441227625981809 1.2467805090850692 1.1057789632550814 0.9928536885666694 0.9575922041775935 1.0805550104641806 0.8610079505342895 0.987314226364806 1.0 16.742062988410993 -5.922244273438231 2.1769867140887973 0.9761204551285868 1.2980663427987762 0.6989077951580651 0.08626475405094293 0.15712079392999256 1.51038536687396 0.02593633406620175 0.04307595575039554 1.1960676014421857e-06 5.922244273438231 0.3219458876701894 DLEDSLAR ddPTM_PC-9_Lapatinib_30min_R1 3 DLEDSLAR 8 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ;; 134.81 0.016349000000000002 20336200.0 107585.0 117005.0 125742.0 101301.0 115243.0 116479.0 114905.0 112880.0 110246.0 101762.0 False True 106050.81817132713 116734.0821112658 115403.97813815677 108751.01347022946 108464.6333164555 111497.4646958107 120854.21866551714 118124.81688869985 97828.93453815325 119351.42611065815 0.888559287703867 0.9780702746109992 0.9669258415995678 0.9111831924773116 0.908783722583182 0.9341946579878689 1.0125913246605505 0.9897227099672773 0.8196712659926655 1.0 16.864856279486432 -7.0512489930233615 24.996575988115843 0.9573188919539879 0.9329860576573414 0.04242474229212012 0.05576104962581318 1414.7827569794429 690052.170918174 0.02135336059556791 0.0165404216899614 8.886914604082286e-08 7.0512489930233615 -0.024332834296646455 DLEEDHACIPIK ddPTM_PC-9_Lapatinib_30min_R1 2 DLEEDHACIPIK 12 0 P13639 P13639 EEF2 Elongation factor 2 0 ; 111.86 0.00078076 0.0 33656.0 33768.0 32835.0 38438.0 38184.0 29923.0 39684.0 39439.0 35716.0 36899.0 False True 33176.05926824551 33689.81227069975 30135.433046765345 41264.85874540908 35938.09219263237 28643.263043919902 41738.64334469674 41271.47991914806 31693.287973846473 43276.94298517306 0.7665989550050203 0.7784702418154186 0.6963392274978832 0.9535067844220575 0.8304212292662395 0.6618596663293259 0.9644545216374607 0.9536597798344472 0.7323365697226993 1.0 15.401310972616747 -14.522878505076767 0.05700559333022212 1.6766978247176663 0.5188452967951686 0.2530744798839396 0.10216121757849875 632.7156577421379 2.6350973583891304 61.233285000844454 11.09185753883391 3.000001659267944e-15 14.522878505076767 -1.1578525279224978 DLEEDHACIPIKK ddPTM_PC-9_AZD4547_30min_R2 4 DLEEDHACIPIKK 13 1 P13639 P13639 EEF2 Elongation factor 2 0 ;;; 72.289 0.0094968 23939800.0 205419.0 205062.0 244381.0 275516.0 281321.0 268805.0 228416.0 283277.0 227732.0 262234.0 False True 270737.96901936806 271344.2812940294 241140.3482642913 212000.04287976737 242264.4351039314 251996.58085650537 248744.58149957572 239503.04870787475 239769.4485959076 253053.2674778172 1.0698852922067135 1.0722812789517353 0.9529232744857951 0.8377684469075327 0.9573653702186179 0.9958242522143902 0.9829732055184027 0.9464530969902206 0.9475058393265993 1.0 17.9490815772901 -5.265573951875191 8.212284889354942 0.9493152127908695 1.0713355620674205 0.5488252864250822 0.04289076516676101 0.08373655363961821 65.81866939676453 0.011957278117052814 0.027511734813183728 5.42532860704204e-06 5.265573951875191 0.12202034927655103 DLEEDHACIPIKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DLEEDHACIPIKK 13 1 P13639 P13639 EEF2 Elongation factor 2 0 ; 93.345 0.0016537 12901700.0 179644.0 150729.0 177389.0 204432.0 226837.0 190684.0 203499.0 177792.0 188961.0 160101.0 False True 210054.18106926754 165692.37898674188 181618.62651152915 192978.33781748638 182389.91821302928 180684.19536000298 184222.1015148261 173125.14838619527 191724.19714590948 189126.04394118095 1.1106570871571517 0.8760949868875434 0.9603046874285244 1.0203689232642306 0.964382876161431 0.9553639022671916 0.9740705070324424 0.9153955995613062 1.0137376807053426 1.0 17.528988520313632 DLEEDHACIPIKK ddPTM_PC-9_Lapatinib_30min_R1 4 DLEEDHACIPIKK 13 1 P13639 P13639 EEF2 Elongation factor 2 0 ;;; 71.153 0.010537000000000001 32604300.0 261862.0 285556.0 317394.0 306574.0 319612.0 283922.0 304351.0 276956.0 285013.0 270244.0 False True 258127.7998603908 284894.812626509 291299.0904962706 329120.4746608845 300813.05054136855 271779.3179145079 320108.8055791198 289824.386837587 252911.8346200556 316955.3153225051 0.8143980787883089 0.8988485090922858 0.9190541266041587 1.0383813072388492 0.9490708500511764 0.8574688758191981 1.0099493212581276 0.9144014087370262 0.7979416100427764 1.0 18.27391993654699 -4.797129817075735 2.197828854597641 0.9363352026080249 0.7854993678958662 0.2279293563611312 0.06794263517255099 0.9742745004508399 5.64022131701157 0.018252659029877643 0.289096921011899 1.5954021865283015e-05 4.797129817075735 -0.15083583471215878 DLEELVMT(ph)S(ph)RK ddPTM_PC-9_AZD4547_30min_R2 1 DLEELVMTSRK 11 1 B1AM31;Q5T1B0 B1AM31 AXDND1 Axonemal dynein light chain domain-containing protein 1 2 DLEELVMT(1)S(1)RK 62.89 0.033014999999999996 4686500.0 22143.0 21548.0 27142.0 25399.0 23612.0 27983.0 34887.0 33475.0 30861.0 34549.0 True False 29184.013396988015 28512.96960589359 26782.079345732243 19543.65296063824 20333.881372787764 26233.21858636403 37991.875414925766 28302.207928974527 32492.249456019825 33339.45002589716 0.875359772711268 0.8552321524123976 0.8033149714505988 0.5862020202929944 0.6099045232297764 0.786852169606481 1.139547154659562 0.8489104621399021 0.9745886459068984 1.0 15.024942685089881 -7.079961659181551 8.089606463942276 0.9772032316179882 0.7416609894374437 0.5331313363459642 0.10930173226737414 0.29020692090101724 26.78481538602595 0.04532828129302826 0.035140576847523024 8.318372049426234e-08 7.079961659181551 -0.23554224218054443 DLEEWNQR ddPTM_PC-9_AZD4547_30min_R2 1 DLEEWNQR 8 0 P09497-2;P09497 P09497-2 CLTB Clathrin light chain B 0 127.46 0.016649 6006600.0 23345.0 22836.0 34475.0 50902.0 37960.0 38431.0 27548.0 48753.0 32257.0 26501.0 False True 30768.224393834862 30217.2904176808 34017.83897443515 39167.330328060474 32689.909237295582 36027.9034947131 29999.71863245264 41219.34408248832 33962.03916602932 25573.20805627661 1.2031429270088467 1.1815995220929805 1.3302139840873783 1.5315767283427455 1.2782873844125422 1.4088143894747114 1.1730917203048994 1.611817492423348 1.328032020515071 1.0 14.64234553178218 -5.309194633074973 5.233443558708254 1.3577892098577033 1.191778263036766 0.09143847674281846 0.16348090407576865 0.34866732543146256 22.738002537098527 0.040444931145405975 0.08972541893265615 4.906879205544357e-06 5.309194633074973 -0.16601094682093742 DLEEWNQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DLEEWNQR 8 0 P09497-2;P09497 P09497-2 CLTB Clathrin light chain B 0 ; 115.49 0.016732 8643300.0 38924.0 56628.0 58691.0 55319.0 67626.0 55811.0 58427.0 54183.0 59746.0 41376.0 False True 45513.064415956906 62249.65359858579 60090.41602685703 52219.65577661784 54375.17075730298 52884.172910349684 52892.37158515143 52760.75366163393 60619.67222167277 48877.14126776424 0.931172798478989 1.273594403927242 1.229417565517242 1.068386047591087 1.1124867237921878 1.0819817104407494 1.0821494509138845 1.0794566190480341 1.240245862367017 1.0 15.576872286649053 -5.792135255172307 24.990454772743398 1.097924742791328 1.1576150794946554 0.04366968778664104 0.10082469206249826 562.1160967508958 457633.97950844635 0.027675107867357128 0.04105435734355072 1.6138558648599575e-06 5.792135255172307 0.05969033670332746 DLEGLSQR ddPTM_PC-9_AZD4547_30min_R2 2 DLEGLSQR 8 0 P35579 P35579 MYH9 Myosin-9 0 ; 125.81 0.015985 39354000.0 88539.0 84168.0 113046.0 159975.0 119323.0 128983.0 100227.0 132241.0 98713.0 94152.0 False True 116692.56027439464 111373.6600050515 111546.93617705573 123095.23533911184 102757.0611149055 120917.67261998328 109147.00883457348 111806.19204587078 103930.76765341648 90855.76713763835 1.2843715258891146 1.2258292843021221 1.2277364408587526 1.3548422870353798 1.1309910680654731 1.330875038860261 1.2013217462489258 1.2305899291620574 1.143909417395273 1.0 16.471290473060016 -8.661385042337793 1.0621386440108163 0.9994940758287545 1.2542812320503403 0.6298782344356537 0.059857289674053224 0.4241078387731586 0.9958980870502419 0.05309495290057665 0.017063648934472646 2.180795576944475e-09 8.661385042337793 0.25478715622158576 DLEGLSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DLEGLSQR 8 0 P35579 P35579 MYH9 Myosin-9 0 ; 105.14 0.017725 13108500.0 64761.0 83198.0 80342.0 74611.0 88164.0 81560.0 80677.0 85072.0 63042.0 55936.0 False True 75723.75821194607 91457.34760357317 82257.65797873166 70430.7875621257 70888.89709056939 77282.85002182584 73034.69050910133 82838.95014123482 63963.86998625343 66076.75401086768 1.1459969446969467 1.3841077542721172 1.2448804304945533 1.0658935750769765 1.07282656588897 1.1695921081279974 1.1053008217850604 1.253677656859631 0.9680237920847815 1.0 16.011855196339397 -1.522878745286624 0.11757838263458123 0.9491637165993205 1.9573678920869566 0.3371175282824218 0.09797078979892354 118.15663343198491 0.9623036717617386 0.7471361168241575 19.454869525312446 0.029999999999565753 1.522878745286624 1.008204175487636 DLEGLSQR ddPTM_PC-9_Lapatinib_30min_R1 2 DLEGLSQR 8 0 P35579 P35579 MYH9 Myosin-9 0 ; 124.08 0.015285 46801000.0 164588.0 143434.0 154666.0 135760.0 144388.0 143422.0 134505.0 127160.0 137726.0 106323.0 False True 162240.9449382573 143101.8873855587 141949.95850802533 145744.24328208392 135895.38171772994 137288.1753930115 141469.01076198055 133068.31782040285 122213.84756092443 124700.78888350801 1.3010418489799471 1.1475620055558788 1.1383244627315952 1.1687515739634504 1.0897716280261835 1.1009407127429025 1.1344676487502974 1.0671008500572643 0.9800567314381082 1.0 16.928111066426567 -1.522878745280366 0.17011635431408537 0.9773961756968537 2.080319686458325 0.7666725323389703 0.04155235619863002 30.884094520838772 0.33444795057243254 0.11085032983428612 8.66855853596083 0.02999999999999803 1.522878745280366 1.1029235107614714 DLEGSDIDTR ddPTM_PC-9_AZD4547_30min_R2 2 DLEGSDIDTR 10 0 P55060-4;P55060-3;P55060 P55060-4 CSE1L Exportin-2 0 ; 135.71 0.000525 22380000.0 150581.0 144852.0 195494.0 261400.0 215470.0 187833.0 179971.0 214080.0 177828.0 172331.0 False True 198462.62572062708 191672.57626475286 192901.62182648946 201138.26858974097 185555.70978293158 176087.77281680028 195988.07034997625 180998.85506900251 187227.62503694257 166297.74414347427 1.193417425731298 1.1525867488580381 1.159977381653852 1.2095068975572383 1.1158041303485295 1.0588704839247827 1.17853715550637 1.0884023472552027 1.1258578761923008 1.0 17.34340907279683 -14.522878745279469 0.08672261338873176 0.5300888805026297 1.267077828280882 0.6158568896081147 0.038200155886973335 155.02307386400017 0.9366220680426781 13.535680603096605 1.0357368336113628 3.0000000000060015e-15 14.522878745279469 0.7369889477782522 DLEGSDIDTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DLEGSDIDTR 10 0 P55060-4;P55060-3;P55060 P55060-4 CSE1L Exportin-2 0 ; 139.98 0.00056281 15863100.0 114940.0 111774.0 119705.0 153022.0 132660.0 106805.0 124670.0 103792.0 106528.0 91444.0 False True 134397.0718315204 122870.18403136844 122559.22118374048 144448.67344401786 106666.22530777828 101203.95778054325 112860.35506736342 101067.56997671431 108085.77046882427 108022.07332969403 1.244163046392632 1.1374544131953153 1.1345757159250003 1.3372144136055069 0.9874484169751346 0.9368822006559602 1.0447897507290242 0.9356196086724433 1.0005896678073918 1.0 16.720966618579602 -6.291595491490129 21.724177276830677 0.9816638021455469 1.2023036930641733 0.7695063349778244 0.061305652813146205 65.24122851342557 46998.75465247565 0.018676362241810233 0.021183459690407802 5.1098071363424e-07 6.291595491490129 0.22063989091862635 DLEGSDIDTR ddPTM_PC-9_Lapatinib_30min_R1 4 DLEGSDIDTR 10 0 P55060-4;P55060-3;P55060 P55060-4 CSE1L Exportin-2 0 ;;; 159.28 0.00066377 35191500.0 282101.0 269256.0 299794.0 237329.0 236736.0 265105.0 237142.0 232752.0 256246.0 188410.0 False True 278078.1880090126 268632.55427503947 275146.0945583055 254782.96636633584 222811.6539208837 253767.07713993898 249420.0524152826 243566.50762295033 227384.8770899953 220976.41745945555 1.2584066263995524 1.215661641017996 1.2451378193276617 1.1529871345347658 1.008305123607884 1.1483898601374503 1.1287179658483053 1.1022285111832786 1.0290006495001467 1.0 17.753532888263194 -1.5228787459172943 0.1778281122307881 0.9947992379631541 2.1796463939439454 0.7088636717062629 0.04844743335653835 34.64476986773607 0.3871026172523486 0.12264636459306558 11.052638533355058 0.029999999956000584 1.5228787459172943 1.1848471559807914 DLEIEER ddPTM_PC-9_Lapatinib_30min_R1 1 DLEIEER 7 0 Q6UB99 Q6UB99 ANKRD11 Ankyrin repeat domain-containing protein 11 0 88.029 0.014725 19676000.0 10043.0 8448.2 9279.2 7228.2 9571.3 9123.1 6342.6 8618.3 9263.5 7413.4 False True 9899.784978339367 8428.638711955864 8516.299994747837 7759.785940568341 9008.334951899811 8732.92627998482 6670.988793419857 9018.737680650976 8220.147081020461 8694.796312265426 1.1385873369309536 0.9693888630911224 0.9794709029277902 0.8924632230454783 1.0360604927791222 1.0043853779145586 0.7672392260655193 1.0372569243431935 0.9454099654323823 1.0 13.085936515445638 -4.7497846896303555 3.9897185177000423 0.9553655539693076 1.1616384723797293 0.33511345123768 0.07593195368664357 0.3171620702758741 9.167934671521746 0.01876282331592182 0.19855632189038858 1.7791612469941252e-05 4.7497846896303555 0.20627291841042172 DLELALS(ph)PIHNSSALPTTGR ddPTM_PC-9_AZD4547_30min_R2 2 DLELALSPIHNSSALPTTGR 20 0 A0A087WUU7;Q96GX5-2;Q96GX5-3;Q96GX5 A0A087WUU7 MASTL Serine/threonine-protein kinase greatwall 1 DLELALS(1)PIHNSSALPTTGR;DLELALS(1)PIHNSSALPTTGR 93.712 0.00034394 14792000.0 12502.400000000001 7039.9 28804.0 85465.0 47121.0 28169.0 16077.0 53775.0 21522.0 34660.0 True False 16477.90313392508 9315.410002252189 28422.040139800745 65762.36467108737 40579.062517666076 26407.587976960604 17507.82185472416 45465.309376567755 22659.60898196618 33446.56394968293 0.49266355607453327 0.2785162032269236 0.8497745891792924 1.9661919463542021 1.2132505622614416 0.7895456172026587 0.5234565165217855 1.3593417083131722 0.6774869016756201 1.0 15.029570386309297 -5.420923740337636 5.194631625949284 1.0844635498977315 0.40193759350963654 0.33264751846558094 0.38419521254057687 0.2603260958403072 10.541877176333541 0.10786737834775759 0.22969164356985863 3.793815963944969e-06 5.420923740337636 -0.682525956388095 DLELALS(ph)PIHNSSALPTTGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DLELALSPIHNSSALPTTGR 20 0 A0A087WUU7;Q96GX5-2;Q96GX5-3;Q96GX5 A0A087WUU7 MASTL Serine/threonine-protein kinase greatwall 1 DLELALS(1)PIHNSSALPTTGR;DLELALS(1)PIHNSSALPTTGR 60.521 0.0076243 6105000.0 11029.1 10268.7 21271.9 15333.7 22853.1 23101.8 17042.2 15452.4 19948.2 12553.7 True False 12896.108795345568 11288.108672525923 21779.10277012999 14474.602501526133 18375.199107351003 21890.30093960539 15427.839441156777 15046.790873171143 20239.904686713297 14829.586434965477 0.8696202589263636 0.7611883663802389 1.468625093871722 0.9760624522473293 1.2390904620256715 1.4761234937740426 1.0403418536865416 1.0146466955877838 1.3648327130007665 1.0 13.856190744264183 -5.238640756065461 24.909306765757762 1.1959083400745139 0.8154042145725655 0.41225641202048147 0.18246723238883886 724.5062675897666 791577.7892480784 0.04518156474686753 0.11935353211619511 5.7724375606504754e-06 5.238640756065461 -0.38050412550194834 DLELALS(ph)PIHNSSALPTTGR ddPTM_PC-9_Lapatinib_30min_R1 2 DLELALSPIHNSSALPTTGR 20 0 A0A087WUU7;Q96GX5-2;Q96GX5-3;Q96GX5 A0A087WUU7 MASTL Serine/threonine-protein kinase greatwall 1 DLELALS(1)PIHNSSALPTTGR;DLELALS(1)PIHNSSALPTTGR 57.648 0.010551000000000001 7301100.0 21017.8 16672.9 29712.0 19013.9 19985.4 26792.9 16480.4 21913.0 34194.0 18263.1 True False 20718.082317807522 16634.294924429923 27269.194051636758 20412.245634511008 18809.898064808174 25647.030124300432 17333.674472783492 22931.157977339484 30342.71164121698 21419.852500948924 0.967237394229941 0.7765830751492339 1.2730803842103349 0.9529592061199638 0.8781525486216525 1.1973485869318774 0.8092340725509474 1.0705562970764437 1.4165695884167626 1.0 14.386660925142651 -8.009311402939968 24.906221782703096 1.2200442133967846 0.9829178510782832 0.21495985506812365 0.17380327252480643 564.436410298725 1509751.5406508073 0.09788588553586398 0.04290412307929689 9.78787911707881e-09 8.009311402939968 -0.23712636231850137 DLELPSQEAPSFQGT(ph)ESPKPCK ddPTM_PC-9_Lapatinib_30min_R1 2 DLELPSQEAPSFQGTESPKPCK 22 1 K7EPV3;Q6PJF5-2;Q6PJF5 K7EPV3 RHBDF2 Inactive rhomboid protein 2 1 DLELPS(0.001)QEAPS(0.046)FQGT(0.476)ES(0.476)PKPCK;DLELPSQEAPS(0.003)FQGT(0.561)ES(0.436)PKPCK 74.206 0.00069969 12034000.0 137142.0 157398.0 58480.0 44530.0 77342.0 55737.0 58626.0 47879.0 84051.0 34954.0 True False 135186.32993123724 157033.5546015046 53672.000139328135 47804.88474772536 72792.89562022244 53353.25843929301 61661.36742077894 50103.63313088292 74584.29128373187 40995.75232672266 3.2975691933604896 3.8304835425387207 1.309208810502609 1.166093608106912 1.775620435992661 1.3014338171936715 1.5040916173304524 1.2221664510892116 1.8193175402495267 1.0 15.323186815752479 -5.264232373836598 24.999967905059734 1.4022571916130704 3.564026489499197 0.9116509679628412 0.2710256605982901 53.088102466212916 475193.7996328812 0.06566505689793414 0.147241064191185 5.442113888921039e-06 5.264232373836598 2.1617692978861265 DLELPSQEAPSFQGTES(ph)PKPCK ddPTM_PC-9_AZD4547_30min_R2 1 DLELPSQEAPSFQGTESPKPCK 22 1 K7EPV3;Q6PJF5-2;Q6PJF5 K7EPV3 RHBDF2 Inactive rhomboid protein 2 1 DLELPSQEAPS(0.014)FQGT(0.443)ES(0.543)PKPCK 50.945 0.015716 7629400.0 27265.0 57423.0 33322.0 36783.0 39502.0 37996.0 49485.0 52279.0 42049.0 31000.0 True False 35934.70285276965 75983.86178203207 32880.12850779199 28303.247641684964 34017.82915415306 35620.10411347919 53889.069134852565 44200.48180190769 44271.62429526513 29914.699435665632 1.201238973837949 2.5400175571024035 1.099129495802015 0.9461317738643423 1.1371609876044917 1.1907224470058129 1.8014243883929393 1.4775505900356771 1.4799287684797038 1.0 14.868566947310727 -5.3022958504255 24.98463153392714 1.2838976547553076 1.8706302003192379 0.27951229638162955 0.38716463225647463 566.6241527505667 346502.12640452146 0.10081316969669929 0.20986280420493597 4.985447527109019e-06 5.3022958504255 0.5867325455639303 DLENGSHIR ddPTM_PC-9_AZD4547_30min_R2 1 DLENGSHIR 9 0 P25205;J3KQ69;A0A499FHX9;P25205-2 P25205 MCM3 DNA replication licensing factor MCM3 0 146.11 0.00038265 3088900.0 19601.0 21611.0 28574.0 40427.0 35522.0 27440.0 24104.0 29564.0 26047.0 26109.0 False True 25833.710273872628 28596.333123861445 28195.09009008005 31107.179740923733 30590.383454352326 25724.1724622031 26249.209304364667 24995.563113135282 27423.791243995594 25194.9318569611 1.0253534488816267 1.1350033921985216 1.1190778466936016 1.234660205374961 1.2141482909349692 1.021005835945366 1.041844822339231 0.992086950464574 1.088464592787485 1.0 14.620845933902075 -6.7797130554587195 24.988448197271826 1.02900860818786 1.1485261659762802 0.5018102617547612 0.05823699011873909 216.3312195418005 295821.50876207516 0.02161883119188649 0.01910116222622044 1.660683782432607e-07 6.7797130554587195 0.11951755778842021 DLENGSHIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLENGSHIR 9 0 P25205;J3KQ69;A0A499FHX9;P25205-2 P25205 MCM3 DNA replication licensing factor MCM3 0 117.7 0.0015463 2657700.0 23816.0 21236.0 26631.0 26489.0 27804.0 24330.0 26050.0 21356.0 20453.0 20126.0 False True 27847.578412558585 23344.16973616529 27265.984038629915 25004.907208496712 22356.005792684024 23054.091969482844 23582.355414332313 20795.427628552403 20752.08643172554 23774.684482671666 1.1713122179541635 0.9818918839145833 1.146849459074963 1.0517450705485367 0.9403281801269895 0.9696907644047167 0.9919103419235896 0.8746878489053886 0.8728648511340217 1.0 14.537138574544631 -6.184922120410921 3.5039122593318552 0.938351466091138 1.0897183790650375 0.5819154162500784 0.061453445075269224 0.1829210757686852 4.362032385682103 0.018856211825822183 0.02464185404382028 6.53247685381512e-07 6.184922120410921 0.1513669129738996 DLENGSHIR ddPTM_PC-9_Lapatinib_30min_R1 1 DLENGSHIR 9 0 P25205;J3KQ69;A0A499FHX9;P25205-2 P25205 MCM3 DNA replication licensing factor MCM3 0 112.11 0.0018382000000000001 3784100.0 15897.0 12542.0 12693.0 13170.0 13468.0 14554.0 13547.0 9938.2 13245.0 11124.0 False True 15670.305864847243 12512.959769578183 11649.430536396914 14138.565733832082 12675.83871910677 13931.559347031054 14248.397374019925 10399.965053182828 11753.208623966757 13046.768578201712 1.2010871328728008 0.9590849791330394 0.8928977674870816 1.0836833388349145 0.971569216019154 1.0678168516231392 1.0921016410014255 0.7971295720350929 0.9008520809975729 1.0 13.67140490408468 -7.754684942080342 24.999963331334932 0.8867431140446185 1.0299913441758553 0.3159977520371624 0.09259448316153532 177.96880617613365 658716.3879662462 0.04430780556133381 0.024839723780977343 1.7591993582340376e-08 7.754684942080342 0.14324823013123678 DLESAEER ddPTM_PC-9_Lapatinib_30min_R1 1 DLESAEER 8 0 O43242 O43242 PSMD3 26S proteasome non-ATPase regulatory subunit 3 0 95.815 0.029077 5699000.0 23705.0 29734.0 33448.0 26456.0 35424.0 33005.0 31736.0 27493.0 30257.0 30739.0 False True 23366.962353035393 29665.152749851528 30698.034553013782 28401.662494628847 33340.42996626361 31593.453088412814 33379.13479455941 28770.425148130988 26849.13803966492 36052.19519285712 0.6481425674091822 0.8228390141338457 0.8514886372049784 0.7877928748221122 0.9247822438526356 0.8763253643615105 0.925855821427836 0.7980214517930703 0.744729631470109 1.0 15.137799486378343 -4.162282299549229 1.3415692586873371 0.8614342379310477 1.1830298456224434e-16 0.4494461513775808 0.07126174367555842 5.702115024859155 2.805396519949623 0.02043631696995467 10.070737959721484 6.882048049052338e-05 4.162282299549229 -0.8614342379310476 DLESAEERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLESAEERR 9 1 O43242 O43242 PSMD3 26S proteasome non-ATPase regulatory subunit 3 0 76.679 0.01529 4913000.0 18654.0 10809.0 16194.0 21914.0 25251.0 25672.0 17803.0 27261.0 21348.0 18149.0 False True 21811.753766705915 11882.04608580762 16580.126376086995 20686.229626146593 20303.247815820177 24325.71512702686 16116.570957441767 26545.427635417065 21660.174113551882 21439.270032595054 1.017373900022928 0.5542187801983384 0.7733531202731954 0.9648756508358922 0.9470120850641028 1.1346335528235532 0.7517313291422256 1.2381684448705061 1.010303712795304 1.0 14.387968165089383 -5.820230266035008 3.438767805796648 1.0141631029366807 0.7554722989373229 0.3010859164871642 0.1572990345730479 0.26024070943750977 6.215471660743816 0.04378023594516993 0.0715153966703185 1.512758960164297e-06 5.820230266035008 -0.25869080399935773 DLEWVER ddPTM_PC-9_AZD4547_30min_R2 1 DLEWVER 7 0 H7C2Q8;Q99848 H7C2Q8 EBNA1BP2 Probable rRNA-processing protein EBP2 0 89.55 0.027837999999999998 0.0 9279.0 8219.9 11435.0 14757.0 10743.0 12548.0 9216.2 11257.0 9875.6 10385.0 False True 12229.528984810182 10876.821926094522 11283.364428503732 11355.001643377242 9251.519887678252 11763.371576374793 10036.42394585487 9517.489310125955 10397.604054563019 10021.424310947992 1.220338407530547 1.085356890258807 1.1259242277744015 1.1330726342933481 0.9231741517591815 1.1738223241903645 1.0014967567923945 0.9497142337071279 1.0375375527412871 1.0 13.290799947993776 -1.522878745284054 0.2642914232837746 0.9863596635967439 2.439686018198888 0.4332520488626356 0.0702793305859545 49.25225060303361 0.6833485344812241 0.08290163378743183 32.415287105528044 0.02999999999974328 1.522878745284054 1.4533263546021442 DLEWVER ddPTM_PC-9_Lapatinib_30min_R1 1 DLEWVER 7 0 H7C2Q8;Q99848 H7C2Q8 EBNA1BP2 Probable rRNA-processing protein EBP2 0 110.81 0.043358 4740400.0 16502.0 15232.0 14404.0 16742.0 15142.0 13440.0 15496.0 14386.0 18667.0 13928.0 False True 16266.678453903822 15196.731239851284 13219.758721047907 17973.262529674772 14251.3773303174 12865.202530170227 16298.307057489672 15054.426078675022 16564.52588777557 16335.436242106565 0.9957908814197742 0.9302923420361354 0.8092687899556902 1.1002621701247568 0.8724209821579634 0.7875640625383857 0.9977270772529975 0.921580902741392 1.0140240910786635 1.0 13.995717362389094 -8.152513831477822 1.8601743008387663 1.008580622688028 0.9215795855683585 0.10894676993787689 0.0877689679455607 0.8192354476313436 5.060199616233198 0.0800687806432151 0.024545856150883758 7.0385981094337925e-09 8.152513831477822 -0.08700103711966956 DLFAFQES(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 3 DLFAFQESPPR 11 0 E7EX48;P51957-3;P51957-2;P51957 E7EX48 NEK4 Serine/threonine-protein kinase Nek4 1 DLFAFQES(1)PPR;DLFAFQES(1)PPR;DLFAFQES(1)PPR 145.83 0.00021400000000000002 3483900.0 18013.699999999997 20192.0 28022.1 32888.3 27529.7 27661.1 23940.9 30644.6 21082.9 24872.1 True False 23741.681891763656 26718.66912391885 27650.508644685127 25306.410554169805 23707.67635221224 25931.447044250945 26071.593720331242 25909.181212852982 22197.299052406594 24001.335349478053 0.9891817078535989 1.1132159413163605 1.1520404278375467 1.054375108121646 0.9877648892034584 1.0804168462574673 1.0862559662080722 1.0794891548988927 0.9248360030471934 1.0 14.550827054069783 -8.251994458445061 24.635354191680996 0.9624180003578499 1.0700763138717695 0.4110039089427371 0.0504250976571065 478.1346798218474 1247136.51857523 0.03629178564852317 0.013304375656285788 5.597647439927023e-09 8.251994458445061 0.10765831351391963 DLFAFQES(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DLFAFQESPPR 11 0 E7EX48;P51957-3;P51957-2;P51957 E7EX48 NEK4 Serine/threonine-protein kinase Nek4 1 DLFAFQES(1)PPR;DLFAFQES(1)PPR;DLFAFQES(1)PPR 118.73 0.0010348 5621700.0 19739.1 19509.6 21304.9 24099.399999999998 24831.199999999997 23307.800000000003 25224.9 21477.4 19390.6 18362.4 True False 23080.539765003992 21446.384153545398 21812.88961528319 22749.188749308985 19965.704612260673 22085.497936963126 22835.41485953902 20913.641007186325 19674.150841588857 21691.357763321594 1.0640431095572724 0.9887063957706499 1.0056027775341523 1.0487673937947812 0.9204451298120735 1.018170378172822 1.0527425303985323 0.9641462390404012 0.9070041191638231 1.0 14.404832740402101 -1.5228787452807007 0.3082530467395124 0.9750672863188807 1.5873488546037995 0.18364881398073696 0.04600079255907347 112.00171020227708 1.5988424964374681 0.04715628755659943 38.16710951697435 0.029999999999974918 1.5228787452807007 0.6122815682849188 DLFAFQES(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 4 DLFAFQESPPR 11 0 E7EX48;P51957-3;P51957-2;P51957 E7EX48 NEK4 Serine/threonine-protein kinase Nek4 1 DLFAFQES(1)PPR;DLFAFQES(1)PPR;DLFAFQES(1)PPR;DLFAFQES(1)PPR 125.03 0.00048152 8700300.0 33343.2 27493.3 28488.8 28172.199999999997 23516.5 26226.4 25416.199999999997 24622.500000000004 30043.600000000002 20887.800000000003 True False 32867.71985360601 27429.6409530333 26146.560833948202 30244.077567704204 22133.305705217877 25104.758008724413 26732.1264735783 25766.551238855533 26659.773394866545 24498.22839875601 1.341636599945937 1.119658144522244 1.067283740210206 1.2345414156249748 0.9034655626911282 1.0247581008755393 1.0911861069486855 1.0517720228359013 1.0882327065013524 1.0 14.580389803359264 -1.5228788710246388 0.8379860392146183 1.0489081211065578 93.45515646423387 0.5505363458276429 0.07765760683732491 483.80142923742443 1.4248291234215846 0.027095357994453933 85146.20475413602 0.029999991313892648 1.5228788710246388 92.4062483431273 DLFDLNS(ph)SEEDDTEGFSER ddPTM_PC-9_AZD4547_30min_R2 1 DLFDLNSSEEDDTEGFSER 19 0 Q9Y3T9 Q9Y3T9 NOC2L Nucleolar complex protein 2 homolog 1 DLFDLNS(0.986)S(0.014)EEDDTEGFSER 102.33 0.00274 0.0 2390.2 2088.0 2609.3 4105.2 1196.1 3013.6 1233.1 2634.4 3528.3 2430.4 True False 3150.233880751511 2762.9051669345563 2574.698977113668 3158.80956470775 1030.042161188863 2825.159115601139 1342.8435111687731 2227.3140124896363 3714.7987348327865 2345.3124357561856 1.3432043563678966 1.1780542007162167 1.0978063894005332 1.3468608772755144 0.4391918728972042 1.2045981902152152 0.5725648705460464 0.9496875463296199 1.5839248870204559 1.0 11.195564411876486 DLFDLNS(ph)SEEDDTEGFSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLFDLNSSEEDDTEGFSER 19 0 Q9Y3T9 Q9Y3T9 NOC2L Nucleolar complex protein 2 homolog 1 DLFDLNS(0.968)S(0.031)EEDDT(0.001)EGFSER 104.03 0.0026452 0.0 2190.8 801.32 2039.6 1221.9 801.62 2150.3 1821.7 2916.4 1233.4 1001.0 True False 2561.659169727633 880.8697538606127 2088.2317992260746 1153.4409044532497 644.5483154773193 2037.5344826131927 1649.1353880341346 2839.847590181224 1251.4361416364475 1182.4733760883594 2.166356741326086 0.7449383399857541 1.7659863143252987 0.9754476741530117 0.5450848437784666 1.7231123539993678 1.3946490647337029 2.401616516369683 1.0583207765541565 1.0 10.20759198567479 DLFDLNS(ph)SEEDDTEGFSER ddPTM_PC-9_Lapatinib_30min_R1 1 DLFDLNSSEEDDTEGFSER 19 0 Q9Y3T9 Q9Y3T9 NOC2L Nucleolar complex protein 2 homolog 1 DLFDLNS(0.893)S(0.107)EEDDTEGFSER 93.115 0.00083785 1210600.0 2556.3 2150.8 2269.3 1079.9 2963.7 2347.4 2278.0 2262.1 3358.3 3136.3 True False 2519.846693231994 2145.8199547447584 2082.7269137513204 1159.3194484407952 2789.3809928583873 2247.007174056665 2395.9436936603947 2367.2054242020554 2980.052889533225 3678.405276142936 0.6850378096114054 0.5833560452574166 0.5662037642397045 0.3151690369627847 0.7583125793532047 0.6108644929992076 0.6513539193736445 0.6435412213969622 0.8101480576001179 1.0 11.844864725170691 -8.577908282251295 0.6699214525221114 1.0064959050297144 0.5682890522281672 0.5943260485044712 0.10747245893532835 0.6034349055476292 0.6136029783488903 0.11045954306786143 0.04418210809187527 2.6429668610639653e-09 8.577908282251295 -0.43820685280154725 DLFDLNSS(ph)EEDDTEGFSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLFDLNSSEEDDTEGFSER 19 0 Q9Y3T9 Q9Y3T9 NOC2L Nucleolar complex protein 2 homolog 1 DLFDLNS(0.379)S(0.621)EEDDTEGFSER 119.8 0.00039024 0.0 995.34 2343.3 875.89 2224.0 2795.5 2602.0 1113.7 2443.3 2087.4 937.58 True False 1163.8314031389011 2575.9273376698115 896.7745394313228 2099.396490305283 2247.741842664659 2465.5465394407893 1008.2022735102454 2379.16596389034 2117.9242760271795 1107.555832120804 1.0508105951736426 2.325776509828218 0.8096878851823961 1.8955220399907533 2.0294614298229723 2.22611489907433 0.910294762819937 2.1481228258575396 1.912250574286328 1.0 10.113163711833833 -4.700192070628432 23.27820540581181 1.7122154027253034 1.050761321140023 0.11110171236062794 0.5449503774266414 35616.1464337411 13532554.423441363 0.12929441116708848 366.5765844767014 1.9943800874218023e-05 4.700192070628432 -0.6614540815852803 DLFDYS(ph)PPLHK ddPTM_PC-9_AZD4547_30min_R2 5 DLFDYSPPLHK 11 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 DLFDY(0.001)S(0.999)PPLHK;DLFDYS(1)PPLHK;DLFDYS(1)PPLHK;DLFDY(0.011)S(0.989)PPLHK;DLFDY(0.001)S(0.999)PPLHK 120.87 0.00082363 197451300.0 311989.0 296230.0 333831.0 394100.0 377995.0 354427.0 360472.0 417656.0 324814.0 343945.0 True False 411195.01222566364 391980.5544066202 329404.1828186994 303246.33378430345 325516.9189186395 332264.62366112485 392553.3096732062 353116.8619800991 341983.0049190762 331903.59023871046 1.2388989583689816 1.1810072742048419 0.9924694776027778 0.9136578895281119 0.9807574503322559 1.0010877659447874 1.182732941788534 1.0639139568394897 1.0303685015070687 1.0 18.340404709733015 -5.151161596720802 4.225600519893347 1.022963952747606 1.225319524467274 0.5729043300844954 0.06597304746658814 0.18102815208318201 5.365225390829539 0.019380807864024508 0.05797506345590282 7.060547893118172e-06 5.151161596720802 0.20235557171966811 DLFDYS(ph)PPLHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 DLFDYSPPLHK 11 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 DLFDY(0.002)S(0.998)PPLHK;DLFDYS(1)PPLHK;DLFDYS(1)PPLHK;DLFDYS(1)PPLHK;DLFDY(0.001)S(0.999)PPLHK;DLFDYS(1)PPLHK;DLFDYS(1)PPLHK 128.31 0.00031622 208143900.0 376028.0 534253.0 490776.0 494806.0 541789.0 394073.0 462637.0 407942.0 356028.0 327022.0 True False 439682.1135084646 587290.1070849273 502477.9611183444 467083.62400269514 435629.33471487934 373407.1181541318 418812.674158176 397233.9547502771 361234.23596119863 386308.4998952725 1.1381631872652598 1.5202619337760896 1.3007168137759466 1.2090948662256218 1.1276721450161662 0.9666034225375879 1.084140458394561 1.0282816838303235 0.9350926424324822 1.0 18.55939389578571 -6.210389187306537 1.527139725782975 1.0082143762132563 1.3419470589047222 0.6749588556106427 0.0957067279317918 0.21877105276041234 1.017861438330549 0.03379912925949106 0.04827540428120607 6.160426958417302e-07 6.210389187306537 0.33373268269146594 DLFDYS(ph)PPLHK ddPTM_PC-9_Lapatinib_30min_R1 6 DLFDYSPPLHK 11 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 DLFDYS(1)PPLHK;DLFDY(0.001)S(0.999)PPLHK;DLFDYS(1)PPLHK;DLFDY(0.001)S(0.999)PPLHK;DLFDYS(1)PPLHK;DLFDYS(1)PPLHK 128.57 0.00030349 251072700.0 268540.0 457115.0 563831.0 542276.0 582168.0 549616.0 516561.0 545050.0 580277.0 518511.0 True False 264710.57035579486 456056.5783025615 517474.9916306014 582156.7860197052 547926.0228263257 526110.2048974731 543306.001027615 570375.0128028512 514920.09367229603 608134.9354775205 0.43528262382745453 0.7499266226901702 0.8509213357793185 0.9572822609879884 0.900994155838264 0.865120837835702 0.8933971218098161 0.9379086441646056 0.8467201333664047 1.0 19.214031944726543 -4.611898122577536 1.4513367731218225 0.9082435936599907 0.08384197818576408 0.9160066699002588 0.04376861123948495 0.44335908414029174 0.6361340962085994 0.012021809610865948 0.5958462375572536 2.444003803371938e-05 4.611898122577536 -0.8244016154742266 down DLFEDELVPLFEK ddPTM_PC-9_Lapatinib_30min_R1 1 DLFEDELVPLFEK 13 0 O60506-2;O60506;O60506-4;O60506-3;B7Z645;O60506-5;F6UXX1 O60506-2 SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0 120.86 0.00094989 10367000.0 30050.0 20986.0 28568.0 23410.0 27672.0 25150.0 26104.0 24362.0 30810.0 19304.0 False True 29621.481489504902 20937.40820637599 26219.24931566905 25131.64949347072 26044.38736524521 24074.393127513475 27455.537392147053 25493.94745785353 27339.853356316784 22640.670679036837 1.3083305662376712 0.9247697872202209 1.1580597451093022 1.1100223067481962 1.1503363895204703 1.0633250873528288 1.2126644913204068 1.126024392972535 1.2075549237872603 1.0 14.466629074953744 -7.243802100815466 24.88589283847665 1.147063000856119 1.113078183708394 0.0006080028428862017 0.10464833957349381 3875.7955834762233 5468684.207393252 0.037267759287273175 0.028804532522883817 5.704241437768484e-08 7.243802100815466 -0.03398481714772483 DLFPYEESK ddPTM_PC-9_AZD4547_30min_R2 1 DLFPYEESK 9 0 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 0 120.12 0.0078156 2341800.0 23691.0 20566.0 22802.0 23423.0 19559.0 24286.0 21748.0 25569.0 25056.0 27270.0 False True 31224.245196587766 27213.55730995023 22499.630581437865 18023.18923174258 16843.57046291528 22767.392580796797 23683.52986854145 21617.89856716803 26380.40900716219 26315.285600342 1.1865440364508897 1.0341349785539304 0.8550023329841974 0.6848943046055463 0.6400679330911908 0.8651774837853521 0.899991367307587 0.8214958748875247 1.0024747368434164 1.0 14.68361343206439 -5.068634085626216 2.513649958861003 0.8282621547526203 1.1832383904063113 0.49460785292324805 0.11100793526709671 0.2708142372968365 3.0450610828809994 0.03144199201313341 0.15559267053687145 8.538191955386928e-06 5.068634085626216 0.35497623565369096 DLFSLDSEDPS(ph)PASPPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLFSLDSEDPSPASPPLR 18 0 H3BTX0;Q9BTK6 H3BTX0 PAGR1 PAXIP1-associated glutamate-rich protein 1 1 DLFS(0.001)LDS(0.009)EDPS(0.495)PAS(0.495)PPLR 76.85 0.043247 0.0 2586.5 2916.6 3391.9 2801.5 2809.1 3325.6 3000.8 2413.3 2754.7 2092.3 True False 3024.343364296387 3206.1407728621057 3472.7757598523845 2644.5410375855445 2258.6770202930766 3151.1996816157907 2716.5425000893833 2349.9534321027118 2794.982276119606 2471.617427362313 1.2236292440792256 1.2971832684816718 1.4050620138078969 1.0699637445135568 0.9138457251871361 1.274954467762724 1.0990950581653942 0.9507755553457803 1.130831270720722 1.0 11.271239735687134 -5.77737836502503 24.608334809919004 1.064877772186948 1.3074806534782082 0.5439642483374656 0.10313928772738452 147.506407994548 227736.02662120602 0.02944660378225652 0.043843201232064914 1.669635364657107e-06 5.77737836502503 0.24260288129126018 DLFSLDSEDPSPAS(ph)PPLR ddPTM_PC-9_AZD4547_30min_R2 4 DLFSLDSEDPSPASPPLR 18 0 H3BTX0;Q9BTK6 H3BTX0 PAGR1 PAXIP1-associated glutamate-rich protein 1 1 DLFSLDS(0.001)EDPS(0.007)PAS(0.992)PPLR;DLFSLDSEDPSPAS(1)PPLR;DLFSLDSEDPS(0.034)PAS(0.966)PPLR;DLFSLDSEDPS(0.011)PAS(0.989)PPLR 300.87 1.1884999999999997e-121 47726700.0 32101.190000000002 36959.6 45217.490000000005 56584.2 54307.7 45192.729999999996 40048.3 52812.840000000004 40737.67 48745.9 True False 42308.700673768595 48906.06791562947 44617.876538016906 43539.58690717532 46768.01327413794 42366.82144889866 43612.521116162796 44651.82909633053 42890.98006859835 47039.320878097205 0.8994326423932001 1.0396848211811978 0.9485229740804402 0.9255998193513151 0.9942323231098008 0.9006682209271821 0.927150313865819 0.9492447650774152 0.9118112095995323 1.0 15.521579611218755 -6.758861243005988 24.999911143330863 0.9339386661926048 0.9631236253717069 0.06576161356368404 0.04329911467152095 168.24776664885678 1631482.6154831212 0.013990765017186784 0.013379961816009183 1.7423634692262369e-07 6.758861243005988 0.029184959179102132 DLFSLDSEDPSPAS(ph)PPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 DLFSLDSEDPSPASPPLR 18 0 H3BTX0;Q9BTK6 H3BTX0 PAGR1 PAXIP1-associated glutamate-rich protein 1 1 DLFSLDSEDPS(0.005)PAS(0.995)PPLR;DLFSLDSEDPS(0.038)PAS(0.962)PPLR;DLFSLDSEDPSPAS(1)PPLR;DLFSLDSEDPS(0.034)PAS(0.966)PPLR;DLFSLDSEDPS(0.005)PAS(0.995)PPLR 239.18 1.3512999999999997e-43 38756960.0 35262.3 34863.9 40755.2 47615.6 46732.7 40524.1 42587.8 42215.3 40770.8 33780.4 True False 41231.51092782856 38324.9575845118 41726.9585329567 44947.852303858024 37575.76290849393 38398.94485739911 38553.57527502884 41107.193105807666 41366.99581922433 39904.519114500756 1.0332541737821768 0.9604164749998212 1.0456700007642417 1.1263850135591433 0.941641792516663 0.9622705826179336 0.9661455927937495 1.030138791745767 1.036649400548524 1.0 15.28426451784903 -4.400290855942756 20.896863591916695 1.0080551498084787 10.219945382367914 0.021016766330059333 0.05226839625156417 2208.757042748107 370275.6883996453 0.013368802565563675 16180.135983561755 3.9784063925779726e-05 4.400290855942756 9.211890232559435 DLFSLDSEDPSPAS(ph)PPLR ddPTM_PC-9_Lapatinib_30min_R1 3 DLFSLDSEDPSPASPPLR 18 0 H3BTX0;Q9BTK6 H3BTX0 PAGR1 PAXIP1-associated glutamate-rich protein 1 1 DLFSLDSEDPSPAS(1)PPLR;DLFSLDSEDPS(0.004)PAS(0.996)PPLR;DLFSLDSEDPSPAS(1)PPLR 258.13 2.2063e-65 30273000.0 59401.8 50132.8 54478.9 50638.8 52264.4 50704.7 50482.0 45549.4 61235.4 45033.0 True False 58554.719439044005 50016.72058175008 49999.85513663543 54362.94627808479 49190.310747763884 48536.17817942872 53095.71094967695 47665.79141025997 54338.424414651075 52816.89404729937 1.1086361758911119 0.946983374996613 0.9466640558579384 1.0292719263158654 0.9313366799591102 0.918951768272532 1.005278934087413 0.9024724431461947 1.0288076456368132 1.0 15.688711844357956 -4.7571997914916295 24.985672527925324 0.9644773795719223 1.1086363893087376 0.48452171009997047 0.043476658397541626 101.47396191783498 597950.1654759629 0.010161218178890104 0.07691058034727774 1.7490418796955655e-05 4.7571997914916295 0.1441590097368154 DLGEELEALK ddPTM_PC-9_Lapatinib_30min_R1 2 DLGEELEALK 10 0 P35579;P35749-4;P35749-3;P35749;P35749-2 P35579;P35749-4 MYH9;MYH11 Myosin-9;Myosin-11 0 ; 135.43 0.0005225 1013500.0 14919.0 13495.300000000001 19026.8 16739.0 15457.4 15191.0 19017.9 16307.5 15761.4 16652.6 False True 14706.25232419048 13464.052461998768 17462.48994957195 17970.041899667078 14548.226122417651 14541.316341950584 20002.553806700624 17065.20598345565 13986.18515710001 19530.979721805266 0.7529705387882697 0.6893690257108246 0.8940918580789903 0.9200788775385658 0.7448794852915318 0.7445256996358458 1.024144927270027 0.8737506375270712 0.7161025896455774 1.0 14.253476699708026 -14.522878725903443 0.023858909584276694 2.104648390967788 7.20143977037005e-12 0.2266979802954503 0.1016445843232771 3783.3031897169008 6.795378025825693 427.9444665464408 207.98207430799857 3.000000133850851e-15 14.522878725903443 -2.1046483909605866 DLGGACPPQDHDMQGLAERIS(ph)VL ddPTM_PC-9_AZD4547_30min_R2 1 DLGGACPPQDHDMQGLAERISVL 23 1 Q9BZL6-2;Q9BZL6;Q9BZL6-3 Q9BZL6-2 PRKD2 Serine/threonine-protein kinase D2 1 DLGGACPPQDHDMQGLAERIS(1)VL 57.845 0.011219 6701300.0 13193.0 18079.0 18819.0 18861.0 22495.0 22176.0 22532.0 23675.0 20573.0 16518.0 True False 17388.099568552723 23922.683195885947 18569.447763883833 14512.887849545183 19371.95754196429 20789.331214351896 24537.3043497322 20016.572747377817 21660.446779388065 15939.709847687895 1.0908667557129292 1.5008230027070417 1.1649802876792885 0.9104863255494153 1.2153268614719641 1.3042477819862859 1.539382120766233 1.2557676983236483 1.3588984358162568 1.0 13.960337747578482 -6.726851610817518 4.677342115547107 1.3240174481615727 1.1769585222918957 0.07834789998388991 0.18478403349040734 0.4552278857194058 22.89731509349062 0.0647242665171627 0.06244033351478654 1.8756352632500588e-07 6.726851610817518 -0.14705892586967706 DLGLESTLIS(ph)S(ph)KPQS(ph)HS(ph)LST(ph)SGK ddPTM_PC-9_AZD4547_30min_R2 1 DLGLESTLISSKPQSHSLSTSGK 23 1 Q9NZN5-2;Q9NZN5;E9PMR6 Q9NZN5-2 ARHGEF12 Rho guanine nucleotide exchange factor 12 5 DLGLES(0.051)T(0.051)LIS(0.952)S(0.952)KPQS(0.973)HS(0.883)LS(0.18)T(0.479)S(0.479)GK 46.027 0.017179 18625000.0 4844.5 2474.7 5475.6 9487.1 7631.6 6838.0 7004.2 7703.0 6493.8 8292.6 True False 6384.950228140195 3274.598379603899 5402.989966306514 7299.995669233875 6572.084071004875 6410.4187790286005 7627.56023106667 6512.6783473305695 6837.0490106445495 8002.278598070992 0.7978915192579441 0.40920824481082985 0.6751814373982111 0.9122396302215211 0.8212765889691873 0.8010741816179555 0.9531735414592225 0.8138529879352736 0.854387775538416 1.0 12.966195141420926 -5.630703057617099 4.695685069361913 0.8683593734906317 0.5900160659987199 0.5432178093364715 0.10639524497044345 0.14102498316585366 5.174257315033717 0.027332163930096912 0.04873369963100816 2.340436930603226e-06 5.630703057617099 -0.27834330749191183 DLGSTEDGDGT(ph)DDFLTDKEDEK ddPTM_PC-9_Lapatinib_30min_R1 1 DLGSTEDGDGTDDFLTDKEDEK 22 1 Q15527 Q15527 SURF2 Surfeit locus protein 2 1 DLGS(0.001)T(0.003)EDGDGT(0.982)DDFLT(0.015)DKEDEK 67.168 0.019288999999999997 0.0 4483.9 7537.7 5693.1 7013.0 6441.5 6804.0 8353.8 8612.4 5729.1 6976.2 True False 4419.958763753447 7520.246918764907 5225.03529400152 7528.75941468219 6062.623634476261 6513.008780898671 8786.318888542675 9012.563545111963 5083.8284279024465 8182.026874797811 0.5402034033116849 0.9191178462061386 0.6385991361255017 0.9201582358366718 0.7409684332803022 0.7960141026864589 1.0738560289512369 1.1015074483405038 0.6213409593607666 1.0 12.998242560591768 -7.109605537111016 6.698982738144859 0.9569185777997735 0.7646069357233515 0.2481454576155009 0.1624783280158017 0.3605391448754746 19.31827149795832 0.059777705763505044 0.0462821648886665 7.769524900416923e-08 7.109605537111016 -0.19231164207642204 DLHILPPPLIPT(ph)PPPDDPR ddPTM_PC-9_AZD4547_30min_R2 3 DLHILPPPLIPTPPPDDPR 19 0 Q9NRS6;E9PK26;E9PMW6;Q9NRS6-2 Q9NRS6 SNX15 Sorting nexin-15 1 DLHILPPPLIPT(1)PPPDDPR;DLHILPPPLIPT(1)PPPDDPR;DLHILPPPLIPT(1)PPPDDPR 106.74 0.0050313 12960200.0 32834.4 31265.3 39579.4 50359.0 48612.1 47513.2 37834.1 48250.5 38609.3 40890.9 True False 43275.056202053136 41371.19679873515 39054.551295279445 38749.51058879411 41863.14902092563 44542.19209297189 41201.26160563655 40794.49391118703 40650.10877555183 39459.32203722128 1.096700449167184 1.0484517894075938 0.9897420756099149 0.9820115650299917 1.0609191151697148 1.1288129089231698 1.0441451975979752 1.033836665331105 1.0301775772327588 1.0 15.268078548435524 -3.814438558706188 18.847508523555323 1.0425641631573708 1.0971064010613736 0.0 0.043865415161102844 0.0 0.0 0.010753369748315717 0.0 0.00015330680799996183 3.814438558706188 0.05454223790400281 DLHILPPPLIPT(ph)PPPDDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DLHILPPPLIPTPPPDDPR 19 0 Q9NRS6;E9PK26;E9PMW6;Q9NRS6-2 Q9NRS6 SNX15 Sorting nexin-15 1 DLHILPPPLIPT(1)PPPDDPR;DLHILPPPLIPT(1)PPPDDPR;DLHILPPPLIPT(1)PPPDDPR;DLHILPPPLIPT(1)PPPDDPR 96.50399999999999 0.0013724 18664200.0 55648.2 56920.3 64275.0 66237.1 75466.3 67009.4 72256.9 67344.3 63353.0 57296.4 True False 65068.34115795022 62570.97121084241 65807.55976429494 62526.05003057562 60679.220254367356 63495.309100693215 65412.20333734619 65576.58348218384 64279.417772899185 67683.78376194723 0.961357913836557 0.9244603024989375 0.9722795639757492 0.9237966105808737 0.8965104620596295 0.9381170137298259 0.966438335767538 0.9688669846358665 0.9497018960845681 1.0 16.046522601996834 -8.465388324835457 0.6862963678512957 0.9976208261873828 0.9365461171688041 0.3944029194202714 0.022137940233209665 0.8097965678801988 0.8809545768937117 0.023265960319099145 0.009447690861027435 3.4246143737671675e-09 8.465388324835457 -0.0610747090185787 DLHILPPPLIPT(ph)PPPDDPR ddPTM_PC-9_Lapatinib_30min_R1 3 DLHILPPPLIPTPPPDDPR 19 0 Q9NRS6;E9PK26;E9PMW6;Q9NRS6-2 Q9NRS6 SNX15 Sorting nexin-15 1 DLHILPPPLIPT(1)PPPDDPR;DLHILPPPLIPT(1)PPPDDPR;DLHILPPPLIPT(1)PPPDDPR 100.62 0.00091809 13074600.0 29953.5 30425.800000000003 33160.4 35374.6 29585.6 33358.6 31933.1 25739.0 32816.0 24879.6 True False 29526.357597200855 30355.35092945557 30434.07991484567 37976.16609020626 27845.433175527574 31931.93044069467 33586.43966814168 26934.927904839187 29119.9165122003 29180.00571001686 1.011869493468437 1.0402791291790336 1.0429771747576566 1.3014447792643806 0.9542641441625505 1.0943085740978156 1.1510086736073593 0.9230610909576695 0.9979407407108241 1.0 14.832692545115473 -7.766994224067085 24.99928831536171 0.9703756834713537 1.085451143485124 0.24266058548198366 0.09020779501561056 199.60722419164563 898301.0510895534 0.04755448788411292 0.023846872841882343 1.7100380577219224e-08 7.766994224067085 0.11507546001377023 DLHQGIEAAS(ph)DEEDLR ddPTM_PC-9_AZD4547_30min_R2 2 DLHQGIEAASDEEDLR 16 0 A0A0C4DGG1;Q9UKS6;E9PIY1 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 1 DLHQGIEAAS(1)DEEDLR;DLHQGIEAAS(1)DEEDLR 159.72 2.1949000000000002e-15 18856000.0 42033.0 50686.0 53163.0 45718.0 60676.0 54400.0 51049.0 66766.0 54101.0 49299.0 True False 55398.6196592872 67069.25828124754 52458.0238839129 35178.42143605886 52252.18474399753 50998.35940028603 55592.26210498312 56448.84883004969 56960.66841061949 47573.057015447754 1.1644956858941893 1.4098160279981389 1.1026834762138351 0.7394610235923214 1.098356675439848 1.0720008887325871 1.1685661084788266 1.1865718196692683 1.1973304215477139 1.0 15.537857114526513 -5.400533706362843 7.16097876255963 1.0680434482375871 1.284797548495481 0.29153253775982146 0.13589226947696723 0.3217889403926069 17.37666998211759 0.03786171200655645 0.07934649896635493 3.976182354225032e-06 5.400533706362843 0.21675410025789388 DLHQGIEAAS(ph)DEEDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLHQGIEAASDEEDLR 16 0 A0A0C4DGG1;Q9UKS6;E9PIY1 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 1 DLHQGIEAAS(1)DEEDLR 184.21 7.7178e-08 5396300.0 9654.6 12539.0 14618.0 10159.0 14106.0 12272.0 8351.2 8321.0 9069.9 7676.3 True False 11288.933092958016 13783.78905263592 14966.548559073723 9589.824165922386 11342.030560768277 11628.434716378692 7560.113878547873 8102.582566828271 9202.53012893499 9067.952424442636 1.2449263697644393 1.520055290043402 1.6504882093041688 1.057551221825232 1.2507818777473811 1.282366092375417 0.8337178587494142 0.8935404805375673 1.0148410245437107 1.0 13.146561106574406 -6.651457456281111 0.9024075018048492 0.926889449064962 1.4445116311961113 0.5792924425178394 0.16319909636748034 0.41020871866525976 0.7304580137235059 0.09914947628264198 0.10330026894536015 2.2312207683521272e-07 6.651457456281111 0.5176221821311493 DLHQGIEAAS(ph)DEEDLR ddPTM_PC-9_Lapatinib_30min_R1 2 DLHQGIEAASDEEDLR 16 0 A0A0C4DGG1;Q9UKS6;E9PIY1 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 1 DLHQGIEAAS(1)DEEDLR;DLHQGIEAAS(1)DEEDLR 128.67 4.6151000000000006e-05 0.0 28559.7 37075.9 30775.4 32601.2 39310.4 38976.5 33393.0 34425.5 36431.0 29652.1 True False 28152.433440792465 36990.053031486495 28245.165408479465 34998.80100241509 36998.23955922001 37309.56595365921 35121.92614679612 36025.0344064665 32327.757144562685 34777.425976060345 0.8095030799626082 1.0636225078000094 0.8121695213418763 1.006365480484586 1.063857905547363 1.07280987325922 1.009905855912767 1.0358740877276245 0.9295615255371708 1.0 15.0858635362021 -5.969976223199152 24.455540941608344 1.0238564163091715 0.9115034284687088 0.3464129502170439 0.07563581702713783 183.44438432159592 149421.06881073833 0.02016853561809405 0.02991433472450382 1.0715779704972778e-06 5.969976223199152 -0.11235298784046266 DLHQGIEAASDEEDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLHQGIEAASDEEDLR 16 0 A0A0C4DGG1;Q9UKS6;E9PIY1 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 0 135.55 4.8172e-07 0.0 8822.9 14150.0 11258.0 9892.9 15205.0 11487.0 12161.0 10610.0 11197.0 8020.7 False True 10316.442709781792 15554.718485907839 11526.433416202757 9338.632886214542 12225.68940000578 10884.601498292215 11009.022041984459 10331.498742224245 11360.734942357152 9474.789418173737 1.0888308177059498 1.6416954297762119 1.2165371606142221 0.9856295980892165 1.2903389046890583 1.14879613866819 1.1619278863198677 1.090419880193563 1.1990488063582663 1.0 13.209878163699639 -1.5228787452807266 0.13004448588462186 0.9702872229993851 2.2046053773566454 0.1772197331171642 0.16093769015725629 132.35195996177617 1.1691266973392664 0.8639040265000074 29.94207999804586 0.029999999999973125 1.5228787452807266 1.2343181543572603 DLHQPSLS(ph)PASPHSQGFER ddPTM_PC-9_AZD4547_30min_R2 1 DLHQPSLSPASPHSQGFER 19 0 F8VQX7;Q9BZF1;F8VVD3;F8VVE7;F8VZ43;Q9BZF1-3;Q9BZF1-2 F8VQX7 OSBPL8 Oxysterol-binding protein;Oxysterol-binding protein-related protein 8 1 DLHQPS(0.037)LS(0.81)PAS(0.151)PHS(0.001)QGFER 65.21300000000001 0.036758 0.0 13033.0 12531.0 21614.0 19890.0 13340.0 22799.0 15763.0 23557.0 17838.0 18632.0 True False 17177.22289675946 16581.40069293914 21327.384237663286 15304.667797436688 11487.971265161297 21373.374925866203 17165.876463022756 19916.80693600757 18780.880263001232 17979.69935113943 0.9553676377614672 0.9222290300359403 1.1861924841536187 0.851219339018969 0.6389412325981563 1.188750407248145 0.9547365686031286 1.1077385971276201 1.0445603063886066 1.0 14.134081276472632 DLIDFDDR ddPTM_PC-9_AZD4547_30min_R2 3 DLIDFDDR 8 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 0 ;; 131.06 0.015285 7018900.0 51454.0 55687.0 69187.0 80412.0 68869.0 70952.0 64302.0 84396.0 65131.0 59330.0 False True 67815.3016903139 73686.73373136247 68269.53517401726 61874.25575301564 59307.728115471815 66515.36022369673 70024.75343052016 71354.53742714656 68573.69169242808 57252.87475864652 1.1844872764240055 1.2870398917433234 1.1924210873569623 1.0807187589068825 1.0358908328269572 1.1617820153851988 1.22307838210246 1.2463048838673443 1.1977335982080421 1.0 15.805060514609119 -11.93792395264934 1.8053769953798562 4.981994058582043e-05 1.1781061148414205 0.3692950795509661 0.07010493942970665 1489473.063471286 133429.92786480812 6064676.779199594 0.020781310185737742 1.1536552515104914e-12 11.93792395264934 1.1780562949008346 DLIDFDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 DLIDFDDR 8 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 0 ;;;; 163.99 6.8725e-05 4528500.0 64577.9 75924.4 78335.5 73914.5 80640.5 62465.9 78615.7 66402.5 63682.1 53799.700000000004 False True 75509.66299833584 83461.67266512077 80203.31540903798 69773.31019904213 64839.57290767294 59190.07823906777 71168.65176762098 64659.50473426442 64613.330237803166 63553.15973180916 1.188133891642563 1.3132576415920851 1.2619878499745971 1.0978731898379508 1.0202415297884853 0.9313475284131686 1.1198286925142475 1.0174081824904375 1.016681633304589 1.0 15.955676234379832 -5.891985578683224 3.021257734538558 1.020643694752414 1.2625526684307915 0.8067969073265127 0.051699248559773335 0.10409845252336743 1.9039511016021693 0.01537333264970326 0.024506607508485104 1.282373164828622e-06 5.891985578683224 0.2419089736783775 DLIDFDDR ddPTM_PC-9_Lapatinib_30min_R1 4 DLIDFDDR 8 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 0 ;;; 160.11 0.00013903 8645600.0 63514.0 96942.0 90855.0 84555.0 94832.0 85598.0 83695.0 86515.0 91654.0 73628.0 False True 62608.27871295888 96717.53675509855 83385.25261044194 90773.45676721104 89254.1682068854 81937.17307868382 88028.31757721984 90534.80273853517 81330.9613605925 86354.50169685701 0.7250146487179324 1.120005730501699 0.9656155842710034 1.0511722606641463 1.0335786375122344 0.9488465739321849 1.0193830761277354 1.0484086059155653 0.941826537846291 1.0 16.39798376756938 -4.7481037822511425 24.998548329706335 1.0141723627305652 0.7250139466419887 0.7418949231239325 0.05119139977422358 318.37322161043363 596779.0215850672 0.01195970561639117 0.2268945738038957 1.7860607134511345e-05 4.7481037822511425 -0.2891584160885765 DLIDNS(ph)FNR ddPTM_PC-9_AZD4547_30min_R2 2 DLIDNSFNR 9 0 Q8IY81 Q8IY81 FTSJ3 pre-rRNA processing protein FTSJ3 1 DLIDNS(1)FNR;DLIDNS(1)FNR 122.18 0.001572 10466000.0 34986.0 36266.0 41949.0 62092.0 56404.0 60734.0 39246.0 52437.0 41178.0 51400.0 True False 46110.82024599298 47988.275279716756 41392.728851010324 47777.64871183705 48573.27820390992 56936.293378988456 42738.81797042385 44334.06653238648 43354.58501344688 49600.501644942364 0.9296442317472969 0.9674957649266033 0.8345223834088185 0.9632493044898229 0.9792900594355745 1.1478975310886619 0.8616610024705631 0.8938229465852008 0.8740755350378121 1.0 15.598067091230368 -4.4944382059103 15.382161412465242 0.9454009891021579 0.8865460655657253 0.003382203736130296 0.08543721537765364 25957084.767111335 433698778.4658383 0.02221731378109958 38410483.74357617 3.203035809840262e-05 4.4944382059103 -0.05885492353643251 DLIDNS(ph)FNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLIDNSFNR 9 0 Q8IY81 Q8IY81 FTSJ3 pre-rRNA processing protein FTSJ3 1 DLIDNS(1)FNR 121.68 0.0016021000000000002 3771900.0 14999.0 13807.0 13238.0 16599.0 18732.0 16012.0 12377.0 10128.0 11928.0 11164.0 True False 17538.034456246474 15177.667712715855 13553.644125394569 15669.011844684092 15061.599068787124 15172.302532484982 11204.560958279882 9862.150731503032 12102.424434441024 13187.944825824623 1.329853490280268 1.1508743714938023 1.0277298172232139 1.1881314375838945 1.1420732546054873 1.1504675469050032 0.8496062962243458 0.7478155892941694 0.917688433966001 1.0 13.686932135904865 -7.257165328284709 10.753835685315597 0.8577010017880076 1.1580600695459418 0.6988505367122986 0.09151791842681706 0.10166095940216517 228.9769635402926 0.03617819003071247 0.026549994284084697 5.5313949863429025e-08 7.257165328284709 0.3003590677579342 DLIDNS(ph)FNR ddPTM_PC-9_Lapatinib_30min_R1 2 DLIDNSFNR 9 0 Q8IY81 Q8IY81 FTSJ3 pre-rRNA processing protein FTSJ3 1 DLIDNS(1)FNR;DLIDNS(1)FNR 133.05 0.0011819 8266100.0 51740.0 48712.0 53473.0 43775.0 51404.0 47681.0 37104.0 30814.0 44334.0 31292.0 True False 51002.17811204608 48599.210356856376 49076.65635174918 46994.3595291192 48380.51778415239 45641.79477983975 39025.0635687337 32245.730932037553 39340.63806228327 36700.78050603095 1.3896755711684392 1.3242010029969304 1.3372101539825436 1.2804730275803464 1.3182422040371087 1.2436191860371892 1.0633306166968521 0.87861158502443 1.0719291938714635 1.0 15.163523124367437 -7.239292725488039 2.2940288227058607 0.978339454611685 1.3265381230569406 0.8998776601008557 0.052003003376935815 0.08538892820661591 0.8811011816273545 0.023876908478036182 0.01589976636356681 5.763778391637244e-08 7.239292725488039 0.3481986684452556 DLIEDSSVQKDGLNQTTIPVS(ph)PPSTTKPSR ddPTM_PC-9_AZD4547_30min_R2 2 DLIEDSSVQKDGLNQTTIPVSPPSTTKPSR 30 2 Q71RC2-5;Q71RC2-3;Q71RC2;Q71RC2-4;X6RLN4;Q71RC2-2;Q71RC2-6 Q71RC2-5 LARP4 La-related protein 4 1 DLIEDSSVQKDGLNQTTIPVS(0.968)PPS(0.015)T(0.003)T(0.01)KPS(0.003)R;DLIEDSSVQKDGLNQT(0.025)T(0.025)IPVS(0.871)PPS(0.025)T(0.025)T(0.02)KPS(0.007)R 104.38 2.0381e-15 30190000.0 72057.0 34134.0 79589.0 137833.0 132857.0 78549.0 63409.0 80907.0 66048.0 88488.0 True False 94969.62712129178 45167.14797324908 78533.59785747131 106057.73134862195 114412.09882875091 73637.31861274011 69052.27816049028 68404.68220790266 69539.16244033557 85390.0620536511 1.1121859480746341 0.5289508742231652 0.9197041900277361 1.2420383449538335 1.3398760473656184 0.8623640367713205 0.8086687900180272 0.8010848166959239 0.8143706746183612 1.0 16.38178055407674 -10.450804918879127 5.1577816927195554 1.000000192003169 0.9350123020084117 0.007025893626682156 0.22548210409840783 5.397040858834016e-07 1.1215996728934802e-07 0.23672034786633692 0.05741294813553005 3.541563891796961e-11 10.450804918879127 -0.06498788999475724 DLIEDSSVQKDGLNQTTIPVS(ph)PPSTTKPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DLIEDSSVQKDGLNQTTIPVSPPSTTKPSR 30 2 Q71RC2-5;Q71RC2-3;Q71RC2;Q71RC2-4;X6RLN4;Q71RC2-2;Q71RC2-6 Q71RC2-5 LARP4 La-related protein 4 1 DLIEDSSVQKDGLNQTT(0.001)IPVS(0.983)PPS(0.009)T(0.003)T(0.003)KPS(0.001)R;DLIEDSSVQKDGLNQT(0.004)T(0.004)IPVS(0.97)PPS(0.007)T(0.007)T(0.007)KPS(0.002)R;DLIEDSSVQKDGLNQTT(0.001)IPVS(0.798)PPS(0.133)T(0.029)T(0.029)KPS(0.009)R 83.31700000000001 5.8930999999999993e-08 26398100.0 91952.0 33861.0 57666.0 116360.0 109793.0 179907.0 110410.0 174641.0 162455.0 114536.0 True False 107517.65746521637 37222.49630044699 59040.97613952287 109840.72644420993 88279.84980564498 170472.36021182718 99951.16550082281 170056.85879743454 164830.59704033507 135300.470133523 0.7946584173662604 0.2751098814639261 0.4363693347204007 0.8118281210391376 0.6524726020428819 1.259953938397955 0.7387347982027316 1.2568829851781873 1.2182559075934465 1.0 17.045807326745525 -6.423005980786937 1.1752343860821817 1.1068335959416842 0.48816636680499403 0.5711044146870494 0.21210343775929083 0.3250988249771668 0.9367663336604554 0.09137760657625779 0.11438898219120847 3.775669913123139e-07 6.423005980786937 -0.6186672291366901 DLIEDSSVQKDGLNQTTIPVS(ph)PPSTTKPSR ddPTM_PC-9_Lapatinib_30min_R1 4 DLIEDSSVQKDGLNQTTIPVSPPSTTKPSR 30 2 Q71RC2-5;Q71RC2-3;Q71RC2;Q71RC2-4;X6RLN4;Q71RC2-2;Q71RC2-6 Q71RC2-5 LARP4 La-related protein 4 1 DLIEDSSVQKDGLNQT(0.001)T(0.001)IPVS(0.858)PPS(0.026)T(0.026)T(0.069)KPS(0.021)R;DLIEDSSVQKDGLNQTT(0.001)IPVS(0.95)PPS(0.033)T(0.011)T(0.003)KPS(0.002)R;DLIEDSSVQKDGLNQTTIPVS(0.61)PPS(0.2)T(0.05)T(0.05)KPS(0.091)R;DLIEDSSVQKDGLNQT(0.001)T(0.003)IPVS(0.795)PPS(0.054)T(0.054)T(0.054)KPS(0.039)R 82.744 1.0962e-07 39491200.0 322249.0 85986.0 114173.0 105700.0 74065.0 84342.0 51496.6 54797.4 113681.0 59942.0 True False 317653.67016677064 85786.9046999643 104786.13666052523 113473.53060486345 69708.64231739263 80734.88927080491 54162.84197320105 57343.487251743856 100877.04866599954 70302.89483230564 4.518358325421362 1.2202471164891981 1.4904953332358915 1.6140662610769196 0.9915472539739582 1.1483864137228323 0.7704212195300968 0.8156632438610953 1.4348918192717783 1.0 16.101296475308516 -4.7611944730640445 7.1742979863466685 1.1611356709978624 4.583917457019253 0.9339884030847244 0.2674863587778781 0.026543721734037556 8.48349710165878 0.07290053515796024 0.4413671650649944 1.7330277901149187e-05 4.7611944730640445 3.4227817860213907 DLIHDQDEDEEEEEGQR ddPTM_PC-9_AZD4547_30min_R2 2 DLIHDQDEDEEEEEGQR 17 0 Q9UNZ2-4;Q9UNZ2;Q9UNZ2-5;F2Z2K0;R4GNE6 Q9UNZ2-4 NSFL1C NSFL1 cofactor p47 0 ; 207.66 1.7497000000000002e-17 119867000.0 323800.0 359840.0 414130.0 599500.0 492850.0 458280.0 386740.0 510060.0 373690.0 418610.0 False True 426761.6645416024 476151.2429452729 408638.36561226496 461294.53718266956 424426.2847102515 429623.67915373266 421159.1107853457 431241.9470127779 393442.49049674487 403954.5913149679 1.0564594974707233 1.1787246714916342 1.01159480396559 1.1419465135451154 1.0506782045195808 1.0635444883921379 1.042590231279147 1.0675505521771227 0.9739770235461277 1.0 18.623833602645014 -7.509875138670485 0.5385458960996617 0.9911446829120495 1.102350304678588 0.36299274431374196 0.04695347991940655 0.9088173142437906 0.5638311477541306 0.04259830276160031 0.030490063246563674 3.0911840320366774e-08 7.509875138670485 0.11120562176653859 DLIHDQDEDEEEEEGQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLIHDQDEDEEEEEGQR 17 0 Q9UNZ2-4;Q9UNZ2;Q9UNZ2-5;F2Z2K0;R4GNE6 Q9UNZ2-4 NSFL1C NSFL1 cofactor p47 0 167.92 1.6886e-05 32877000.0 158960.0 153840.0 166860.0 155360.0 195450.0 172710.0 189110.0 181170.0 162770.0 146410.0 False True 185868.78839688952 169112.21850685982 170838.5752200738 146655.68288391575 157152.97554956484 163652.7835614214 171196.13176216467 176414.47946548226 165150.2033194134 172952.97401907787 1.0746781860853514 0.9777930646523928 0.9877747184690168 0.8479512059025863 0.9086456965592845 0.9462270567453175 0.9898420812542986 1.0200141423761961 0.9548850157453566 1.0 17.40002029627535 -9.770708225282958 12.815925691467571 1.0000013557189298 0.964755337333191 0.025423945395962266 0.05804998235428129 0.0 0.0 0.06036134388773739 0.014639776267845428 1.6954765002379315e-10 9.770708225282958 -0.03524601838573882 DLIHDQDEDEEEEEGQR ddPTM_PC-9_Lapatinib_30min_R1 2 DLIHDQDEDEEEEEGQR 17 0 Q9UNZ2-4;Q9UNZ2;Q9UNZ2-5;F2Z2K0;R4GNE6 Q9UNZ2-4 NSFL1C NSFL1 cofactor p47 0 ; 207.85 1.6849e-17 150459000.0 519830.0 404180.0 436450.0 393330.0 444060.0 455370.0 377190.0 408340.0 457660.0 346140.0 False True 512417.12887485255 403244.146042746 400566.76574572 422256.80031041574 417941.26385555015 435894.8866193164 396719.05259515607 427312.96711846045 406113.51142654807 405969.8377974416 1.262204925506123 0.9932859747180146 0.9866909520149686 1.0401186516745624 1.0294884618105093 1.0737124929877326 0.9772131219095612 1.0525731897640829 1.0003539022255594 1.0 18.631013018407565 -4.75769019444689 24.99099916573839 1.019378338546026 1.2622052727641864 0.8592687385750233 0.029750825504388102 37.22178522221414 248073.71700531113 0.0072814524546725694 0.05292347422866206 1.7470679858294987e-05 4.75769019444689 0.24282693421816037 DLISHDEMFSDIYK ddPTM_PC-9_AZD4547_30min_R2 5 DLISHDEMFSDIYK 14 0 Q5W0H4;A0A0B4J2C3;P13693 Q5W0H4 TPT1 Translationally-controlled tumor protein 0 ;;;; 139.48 2.5699000000000002e-05 22944300.0 231006.0 210508.0 285571.0 353480.0 330313.0 293095.0 250621.0 299025.0 250032.0 267940.0 False True 304461.10277670645 278550.59429169487 281784.1419512231 271990.64721155964 284454.74156740843 274767.72331666923 272925.783482791 252817.55716091415 263248.18106955517 258559.50215458884 1.1775281907631217 1.0773171821979826 1.089823191965881 1.0519460508898277 1.100151954180888 1.0626866196253337 1.0555627668234477 0.9777925585955001 1.0181338487887521 1.0 17.980136799793407 -1.5228787452849277 0.18368427011178623 0.9813055088890598 1.703177969673968 0.7134655127094209 0.028729124404443328 32.266080023587634 0.36865944351358826 0.06528254251556655 6.537454067618748 0.029999999999682923 1.5228787452849277 0.7218724607849082 DLISHDEMFSDIYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DLISHDEMFSDIYK 14 0 Q5W0H4;A0A0B4J2C3;P13693 Q5W0H4 TPT1 Translationally-controlled tumor protein 0 ;;; 102.9 0.00091326 24205700.0 170836.0 180260.0 191102.0 228179.0 245618.0 214492.0 214800.0 222686.0 208630.0 176535.0 False True 199755.16063519716 198155.02150316272 195658.5964383708 215394.87039629917 197490.9160835659 203243.6619284141 194452.58898267066 216840.72845532047 211680.81906081692 208539.39804970942 0.9578773243969066 0.950204246086529 0.938233246418654 1.032873751486305 0.9470196899508174 0.9746055845043105 0.9324501307725033 1.0398070124074696 1.0150639209688266 1.0 17.66996044324557 -7.768497238740107 24.99943597420963 1.0205766060312003 0.9631818622488219 0.4591350975400085 0.027992333164950336 148.80742322244578 527075.8185895057 0.014777844757756836 0.007337262964875667 1.7041301542017372e-08 7.768497238740107 -0.05739474378237841 DLISHDEMFSDIYK ddPTM_PC-9_Lapatinib_30min_R1 4 DLISHDEMFSDIYK 14 0 Q5W0H4;A0A0B4J2C3;P13693 Q5W0H4 TPT1 Translationally-controlled tumor protein 0 ;;; 147.73 9.4027e-06 14022200.0 168282.0 147256.0 159558.0 145817.0 163135.0 152854.0 141093.0 143510.0 155422.0 134374.0 False True 165882.2678208607 146915.0377793819 146439.75715169124 156540.8686112525 153539.72003575013 146316.79074007733 148398.10516664883 150177.9985090123 137916.73769378322 157600.36685789973 1.0525500106889238 0.9321998464118282 0.9291841134083689 0.9932773110382254 0.9742345344550443 0.9284038714960846 0.9416101505680624 0.9529038637608008 0.875104166592047 1.0 17.265911367501765 -6.755128729641536 24.830221191471356 0.9367862596055507 0.9721666016359743 0.14895370469362867 0.04302352437997521 288.4834888821073 1135082.17593308 0.01404940569554506 0.013716287613916812 1.757402623361351e-07 6.755128729641536 0.03538034203042362 DLISLDS(ph)SPAK ddPTM_PC-9_AZD4547_30min_R2 1 DLISLDSSPAK 11 0 Q9UN79 Q9UN79 SOX13 Transcription factor SOX-13 1 DLISLDS(0.517)S(0.483)PAK 107.09 0.002353 3266200.0 35354.0 43552.0 40210.0 28881.0 34944.0 44047.0 45712.0 44995.0 49704.0 47107.0 True False 46595.836591117455 57629.33229422113 39676.78912725271 22222.931657001984 30092.628777346068 41292.73412691912 49780.27944412205 38042.056632239255 52331.25196727288 45457.798268254905 1.0250350515470805 1.267754587543808 0.8728268996468465 0.4888695120221252 0.6619904598054636 0.9083751457394181 1.0950877812066344 0.8368653582328387 1.1512051608495522 1.0 15.472240188993522 -7.0117516060221785 24.207087064389146 1.0064145396878912 0.857462327378353 0.11320972915343241 0.20696417088791041 1054.1339495321172 2171406.2731818105 0.08672429502438621 0.071134917101621 9.733037440044785e-08 7.0117516060221785 -0.14895221230953815 DLISLDS(ph)SPAKER ddPTM_PC-9_AZD4547_30min_R2 3 DLISLDSSPAKER 13 1 Q9UN79 Q9UN79 SOX13 Transcription factor SOX-13 1 DLIS(0.007)LDS(0.496)S(0.496)PAKER;DLIS(0.001)LDS(0.5)S(0.5)PAKER;DLISLDS(0.5)S(0.5)PAKER 121.45 0.00095103 19416400.0 107954.0 87596.0 115462.0 142144.0 137232.0 122659.0 116380.0 117441.0 113964.0 137055.0 True False 142281.1264173074 115909.69396685781 113930.8984384693 109374.89690290797 118179.70559674788 114989.11333969979 126737.59454206603 99293.19197570405 119987.9043778829 132256.74616629537 1.0757948501047174 0.8763991049735693 0.8614373311076039 0.8269891712395789 0.8935627786287176 0.8694385479219048 0.9582694132117107 0.7507608863358546 0.907234661791951 1.0 17.0129817877964 -4.7614738996641695 8.728432480089964 0.8746682431348374 1.0774576226056745 0.4402632090550046 0.06476381646325646 0.07201011348975261 66.61793316015415 0.015000883550200605 0.0862354278172112 1.7319131125596974e-05 4.7614738996641695 0.20278937947083708 DLISLDS(ph)SPAKER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DLISLDSSPAKER 13 1 Q9UN79 Q9UN79 SOX13 Transcription factor SOX-13 1 DLIS(0.015)LDS(0.493)S(0.493)PAKER;DLISLDS(0.775)S(0.225)PAKER 149.3 0.00058334 15630100.0 61577.0 47401.0 55404.0 69092.0 75053.0 67161.0 64453.0 76688.0 64460.0 47975.0 True False 72000.7698988125 52106.658017704365 56725.041480840104 65220.99923928626 60346.903422468495 63638.95892981663 58347.54524068949 74675.02125765235 65402.605553660935 56672.48773010893 1.2704713130240792 0.919434810517788 1.000927323871531 1.1508405904093686 1.064835969612949 1.1229250996159563 1.029556802209878 1.317659136709805 1.1540450785419443 1.0 15.790360912808902 -7.7025333836992615 24.99998938022664 1.1768997948326887 1.0744591848004705 0.07950422275972979 0.11392168602637494 138.9992228189174 58991.25546502126 0.051449199948508155 0.02970418816890372 1.9836571696131834e-08 7.7025333836992615 -0.10244061003221816 DLISLDS(ph)SPAKER ddPTM_PC-9_Lapatinib_30min_R1 2 DLISLDSSPAKER 13 1 Q9UN79 Q9UN79 SOX13 Transcription factor SOX-13 1 DLISLDS(0.5)S(0.5)PAKER;DLISLDS(0.5)S(0.5)PAKER 107.11 0.005041899999999999 12441300.0 114394.0 95543.0 99022.0 100274.0 94999.0 100176.0 83409.0 86915.0 108090.0 84405.0 True False 112762.72058270946 95321.77605364432 90880.79339597383 107648.48446425788 89411.34559522007 95891.70600166156 87727.50989662859 90953.38819880696 95915.76596183976 98994.29178740719 1.139083057686501 0.9629017424393551 0.9180407451284434 1.0874211282347046 0.9031969821778538 0.9686589425538948 0.8861875600365493 0.9187740682476089 0.9689019864682841 1.0 16.59505771840407 -6.281174155759225 24.97756808668421 0.9355389589281361 1.0145201883844186 0.2827911646665334 0.06552181658381594 1149.485575153774 1454857.382551356 0.02013080066093196 0.022855896230735702 5.233905104774964e-07 6.281174155759225 0.0789812294562825 DLISLDSS(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 1 DLISLDSSPAK 11 0 Q9UN79 Q9UN79 SOX13 Transcription factor SOX-13 1 DLISLDS(0.012)S(0.988)PAK 138.45 0.00010143 2993300.0 31951.0 35489.0 31823.0 28261.0 33378.0 41973.0 37401.0 39052.0 38293.0 37302.0 True False 42110.75337791466 46960.12522477992 31401.006227221176 21745.863078097474 28744.040846218424 39348.42167478318 40729.61654466246 33017.410725685266 40317.08980329108 35996.068333845134 1.1698709144387367 1.3045904010751608 0.8723454443966739 0.604117729648019 0.7985327891822 1.0931310972589197 1.1315018120011353 0.9172504735646587 1.1200414842357413 1.0 15.135551716520366 -5.2620799909156855 24.99579135974033 0.9341177246070902 1.2372306724774722 0.36302152053834225 0.15608079069978148 62.446286763970555 2436682.733224213 0.04527123586587321 0.10417846505170023 5.469152195500201e-06 5.2620799909156855 0.303112947870382 DLISLDSS(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLISLDSSPAK 11 0 Q9UN79 Q9UN79 SOX13 Transcription factor SOX-13 1 DLISLDS(0.121)S(0.879)PAK 91.12299999999999 0.0083638 2566100.0 18747.0 26356.0 18739.0 19577.0 20277.0 17147.0 18753.0 20126.0 15131.0 19161.0 True False 21920.49682987217 28972.449499264072 19185.808828053254 18480.164159490352 16303.867409662429 16247.781134431663 16976.58008003738 19597.713825259678 15352.262249960346 22634.737621607466 0.9684449272761407 1.2799993524822895 0.8476267385462506 0.8164514415156686 0.7203029114902798 0.7178250265610008 0.7500232767810516 0.8658246520406493 0.678261109388997 1.0 14.466250962733405 -5.409244012739913 5.437588267186382 0.7827582556630258 1.1213980014719267 0.5772046392631449 0.1115847065658038 0.1339942076098109 5.470295666184884 0.027425455067889324 0.05830085258467288 3.897229553721563e-06 5.409244012739913 0.3386397458089009 DLISLDSS(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 1 DLISLDSSPAK 11 0 Q9UN79 Q9UN79 SOX13 Transcription factor SOX-13 1 DLISLDS(0.008)S(0.992)PAK 113.95 0.0015065 4451600.0 42237.0 61830.0 42990.0 49606.0 60996.0 45660.0 54858.0 56568.0 46013.0 43813.0 True False 41634.69263468282 61686.8364338239 39455.52814619896 53254.190720764964 57408.33520274996 43707.22823865864 57698.27881774451 59196.35579163692 40830.53140162946 51386.01867284717 0.8102338673045119 1.200459541856271 0.7678261356925792 1.036355648796449 1.1171975701843007 0.850566542563336 1.1228400313533689 1.1519934277943351 0.7945844503264596 1.0 15.649088257739477 DLLDLLVEAK ddPTM_PC-9_Lapatinib_30min_R1 1 DLLDLLVEAK 10 0 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDT5;A0A2R8Y7T2;O15523-2;O15523;A0A0J9YVQ7;A0A087WVZ1 A0A2R8Y5G6 DDX3X;DDX3Y ATP-dependent RNA helicase DDX3X;ATP-dependent RNA helicase DDX3Y 0 152.97 1.0373000000000001e-08 0.0 13660.0 12346.0 14680.0 14485.0 13045.0 9950.2 12589.0 10823.0 11310.0 13266.0 False True 13465.205895062803 12317.413595535985 13473.067066438722 15550.275220543488 12277.718747456782 9524.653141049088 13240.796821549926 11325.876091304026 10036.148700420083 15559.010424166127 0.8654281685002766 0.7916579049529191 0.8659334173021997 0.999438575887251 0.7891066599188808 0.6121631698540079 0.851005074267733 0.7279303620564949 0.6450377258461129 1.0 13.925462685275376 -6.509130928447551 24.656972557520973 0.7493674615140112 0.8758444316490356 0.17990828894810318 0.11219881675522017 823.2226549813608 1476468.3847075843 0.03427949434053322 0.03728833186590808 3.0964856489092604e-07 6.509130928447551 0.12647697013502435 DLLHNEDRHDDYFQER ddPTM_PC-9_AZD4547_30min_R2 4 DLLHNEDRHDDYFQER 16 1 Q8N684-2;Q8N684;Q8N684-3 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 0 ;;; 65.956 0.0077598 53040000.0 99969.0 102739.0 149606.0 210088.0 176668.0 138587.0 124268.0 161607.0 129974.0 134056.0 False True 131757.0625156253 135947.372579353 147622.12668917602 161655.4574272439 152140.69771165782 129921.13298175408 135327.61126098543 136634.3515094187 136844.16029282002 129362.740243471 1.0185085927187998 1.0509005322822413 1.1411487296213685 1.249629198662578 1.1760781924170507 1.0043164881729634 1.0461096526425466 1.05621101757942 1.0578328816726392 1.0 16.98106261876451 -6.76615002043478 24.999976029654245 1.0372331704596043 1.1305819014292806 0.36420620840169304 0.06212608784685104 156.57287360897016 830946.9535728386 0.02447948684123138 0.022296285586699497 1.7133653492273437e-07 6.76615002043478 0.09334873096967633 DLLHNEDRHDDYFQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DLLHNEDRHDDYFQER 16 1 Q8N684-2;Q8N684;Q8N684-3 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 0 ;; 71.031 0.0052717 36058000.0 81501.0 68384.0 93878.0 108231.0 122220.0 101947.0 107527.0 94136.0 93839.0 79745.0 False True 95297.50958187522 75172.71158588844 96116.4075542975 102167.16795963624 98271.86836361095 96600.71985256333 97341.26413193534 91665.02974533683 95211.21784905357 94202.13723892713 1.0116278926896305 0.7979936951454306 1.0203208798810495 1.0845525478950357 1.0432021103126532 1.0254620827503373 1.033323308632015 0.9730674104860766 1.0107118653536182 1.0 16.523472171330432 -5.402218449423528 10.673152372348587 1.0265543459683406 0.9049646389469992 0.4274746390098043 0.055069192294180225 0.35873476900367646 30.01243840056006 0.013715404262003577 0.02857011430305704 3.960787571659556e-06 5.402218449423528 -0.12158970702134142 DLLHNEDRHDDYFQER ddPTM_PC-9_Lapatinib_30min_R1 4 DLLHNEDRHDDYFQER 16 1 Q8N684-2;Q8N684;Q8N684-3 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 0 ;;; 73.758 0.003934900000000001 44517800.0 127075.0 121530.0 149486.0 130470.0 129801.0 134657.0 111947.0 116200.0 134915.0 102840.0 False True 125262.8871972992 121248.60475178096 137195.83811264706 140065.1990351612 122166.36037858471 128898.03401079858 117743.06789912209 121599.07620895552 119719.45198206672 120615.7569743134 1.0385283841809778 1.005246808487902 1.1374619830298343 1.16125125397165 1.0128557283324229 1.068666625690116 0.9761831360408153 1.0081524939967133 0.9925689228776506 1.0 16.88005886445901 -6.992893310588331 1.7521999580332903 0.9950339688223585 1.0790076960256583 0.37187823870763626 0.04749017210957013 0.42508014262435345 2.634935066089861 0.023894643440730386 0.018274080504260628 1.0164983766646046e-07 6.992893310588331 0.08397372720329976 DLLHPS(ph)PEEEK ddPTM_PC-9_AZD4547_30min_R2 3 DLLHPSPEEEK 11 0 P42677 P42677 RPS27 40S ribosomal protein S27 1 DLLHPS(1)PEEEK;DLLHPS(1)PEEEK;DLLHPS(1)PEEEK 104.9 0.0026246 33854800.0 178392.0 212230.0 166583.0 144100.0 158400.0 186917.0 208886.0 196019.0 202617.0 160237.0 True False 235116.94521589094 280829.1971161499 164374.00057660148 110879.97132280694 136408.89418302506 175229.0504416041 227476.44933419797 165728.76761851143 213326.92096919645 154627.15140234682 1.520541140954644 1.8161700229827014 1.063034525863397 0.7170795705489799 0.8821794422642047 1.133235973452361 1.471128758896256 1.071796033979037 1.3796213603787486 1.0 17.238434142692 -5.269037817361151 24.76676470354909 1.0867730787954486 1.6683555888265922 0.5346242166459702 0.21591565925142162 368.9245765574153 1202496.4348725132 0.06147639003490494 0.13205282433941196 5.382229132665929e-06 5.269037817361151 0.5815825100311436 DLLHPS(ph)PEEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DLLHPSPEEEK 11 0 P42677 P42677 RPS27 40S ribosomal protein S27 1 DLLHPS(1)PEEEK;DLLHPS(1)PEEEK;DLLHPS(1)PEEEK;DLLHPS(1)PEEEK 131.06 0.00017779 33606500.0 212010.0 323175.0 203674.0 223068.0 235509.0 162001.0 249441.0 168211.0 165934.0 158450.0 True False 247899.1056116291 355257.6782108308 208530.36059794642 210570.2231562138 189362.70206550183 153505.38237353845 225812.14268354952 163795.63948428692 168360.470833714 187175.73071049058 1.3244190615452218 1.8979900698788605 1.1140886684742564 1.1249867830456506 1.0116840540528937 0.820113707000664 1.2064178503612675 0.8750901565205255 0.8994781011119513 1.0 17.51403386099576 -5.412541296840947 5.324328787536249 0.997315691862969 1.6067152893740244 0.6780624957981567 0.16819295175428023 0.11530501003032535 4.644370094135967 0.04254714080445473 0.09055730858895294 3.867752746206386e-06 5.412541296840947 0.6093995975110554 DLLHPS(ph)PEEEK ddPTM_PC-9_Lapatinib_30min_R1 2 DLLHPSPEEEK 11 0 P42677 P42677 RPS27 40S ribosomal protein S27 1 DLLHPS(1)PEEEK;DLLHPS(1)PEEEK 97.631 0.0030096999999999997 32156000.0 371160.0 459850.0 337230.0 376990.0 421690.0 369560.0 446290.0 417430.0 334050.0 368260.0 True False 365867.1903375921 458785.24557809945 309504.2511454443 404715.10220177297 396887.0232744381 353754.78028643626 469396.7124862587 436825.32170313504 296425.7712975533 431913.25032439484 0.8470848950866919 1.062216186314085 0.7165889236159959 0.9370286785547924 0.9189044859733991 0.8190412774341688 1.086784700709486 1.011372819368359 0.6863085841309994 1.0 18.720382050958747 DLLHPSLEEEK ddPTM_PC-9_Lapatinib_30min_R1 2 DLLHPSLEEEK 11 0 H0YMV8;Q71UM5;C9JLI6 H0YMV8 RPS27L 40S ribosomal protein S27;40S ribosomal protein S27-like 0 ; 114.86 0.0011886 4953200.0 46233.0 53823.0 72477.0 66542.0 72521.0 85512.0 91813.0 62201.0 75594.0 65443.0 False True 45573.70894190618 53698.37615037526 66518.22082931049 71435.72065760486 68255.45736177184 81854.85109820802 96566.6278955407 65091.08553591444 67079.80767988999 76754.73535268368 0.5937576194158909 0.6996099446325266 0.8666334464403143 0.9307011525655291 0.889267053663098 1.0664469198166027 1.2581194821638364 0.8480399969698882 0.8739500875309133 1.0 16.227968139271233 -5.139452557495502 0.9425952743780281 1.0017804660881522 0.4882239217561561 0.6055621480831401 0.10975017740945549 0.9539960505043728 0.9774843922664146 0.04294261759966599 0.4460513309068596 7.253497112586691e-06 5.139452557495502 -0.513556544331996 DLLHPSPEEEK ddPTM_PC-9_Lapatinib_30min_R1 1 DLLHPSPEEEK 11 0 P42677 P42677 RPS27 40S ribosomal protein S27 0 72.531 0.022662 6326400.0 60181.0 56637.0 75707.0 77620.0 83632.0 91921.0 76998.0 72067.0 92037.0 69731.0 False True 59322.80790415621 56505.8605062669 69482.6626974711 83328.43373272955 78712.9301868383 87989.75310831673 80984.5796858925 75415.49591351832 81670.82386742382 81783.91043928286 0.7253603744980869 0.6909165898617354 0.8495884132253089 1.0188854175002229 0.9624500682842198 1.0758809726228626 0.9902263079730849 0.9221312053733048 0.9986172515932337 1.0 16.319529425496206 -5.517873738281462 2.8885992913530023 0.9940816167722707 0.7087617962982238 0.8977106412115283 0.038987662899099475 0.0763653049845221 1.2807224575989915 0.01141942683514667 0.02500534582413644 3.0347733506043024e-06 5.517873738281462 -0.2853198204740469 DLLLDPAWEK ddPTM_PC-9_Lapatinib_30min_R1 1 DLLLDPAWEK 10 0 O43707;O43707-2;F5GXS2;O43707-3;K7EP19;D6RH00;P12814-4;P12814-3;P12814;P12814-2;P35609-2;P35609;A0A494C1A0;Q08043;A0A494C033;A0A494C166;A0A494C0Q3 O43707;P12814-4 ACTN4;ACTN3;ACTN1;ACTN2 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2;Alpha-actinin-3 0 129.85 0.0010716 2631200.0 35548.0 32372.0 28138.0 25755.0 29319.0 24806.0 35903.0 33271.0 27459.0 37214.0 False True 35041.07900129519 32297.044622929734 25824.602255821024 27649.108616161382 27594.514063371822 23745.10520561031 37761.88166527183 34816.892121757024 24366.278263911132 43646.39031546196 0.8028402520352687 0.7399705769365384 0.5916778471064656 0.6334798460152739 0.6322290082622554 0.5440336539628681 0.865177655983489 0.7977038162861078 0.558265599693344 1.0 15.413574723224984 -7.270907966715855 24.911180752260265 0.7884287471396407 0.6559113997432268 0.2549696018223081 0.12250491822675152 1076.0038090303717 2830877.733295498 0.050872996736606065 0.03480953293187352 5.359102126086039e-08 7.270907966715855 -0.13251734739641396 DLLPSGSRDEPPPASQSTSQDCSQALKQS(ph)P ddPTM_PC-9_AZD4547_30min_R2 2 DLLPSGSRDEPPPASQSTSQDCSQALKQSP 30 2 Q5JRA6-4;Q5JRA6-2;Q5JRA6 Q5JRA6-4 MIA3 Melanoma inhibitory activity protein 3 1 DLLPSGSRDEPPPASQSTSQDCSQALKQS(0.999)P;DLLPSGSRDEPPPAS(0.024)QS(0.106)T(0.106)S(0.106)QDCS(0.106)QALKQS(0.55)P 105.79 1.5258e-14 15706100.0 35866.0 29884.0 48701.0 56266.0 50392.0 31518.0 35298.0 32699.0 30348.0 39677.0 True False 47270.641940855894 39543.41858652884 48055.192919331916 43294.74300103434 43395.940629236015 29547.174477540706 38439.45361871328 27646.120898268524 31952.133323330065 38287.92030673887 1.2346098080583399 1.0327909761024285 1.2551006305472787 1.1307676847993815 1.133410754137986 0.771710091350672 1.0039577315968176 0.7220585677358575 0.8345225613548491 1.0 15.224601678686632 -6.725900196371436 9.611987391216044 0.8577464601643698 1.1548031620895538 0.6779302809815688 0.10015317850119741 0.19961612613479401 51.56091934674862 0.031502778231695915 0.031307493334909835 1.8797487453645295e-07 6.725900196371436 0.29705670192518396 DLLPSGSRDEPPPASQSTSQDCSQALKQS(ph)P ddPTM_PC-9_Lapatinib_30min_R1 2 DLLPSGSRDEPPPASQSTSQDCSQALKQSP 30 2 Q5JRA6-4;Q5JRA6-2;Q5JRA6 Q5JRA6-4 MIA3 Melanoma inhibitory activity protein 3 1 DLLPSGSRDEPPPASQSTSQDCSQALKQS(1)P;DLLPSGSRDEPPPASQS(0.003)T(0.019)S(0.134)QDCS(0.134)QALKQS(0.71)P 105.91 1.5018000000000002e-14 16992300.0 89207.0 64507.0 45346.0 29427.0 31689.0 45425.0 35157.0 27001.5 53689.0 21923.9 True False 87934.89182143976 64357.638004798304 41617.826920621985 31591.15974559428 29825.115322971098 43482.278640846875 36977.25743547786 28256.08826382202 47641.97944976603 25713.416903239526 3.419805782807543 2.5028815986213857 1.6185257321977589 1.228586611591641 1.1599047857079452 1.691034637849656 1.4380530434607177 1.0988850050598353 1.852806246211635 1.0 14.65023371363448 -5.002223459724997 1.75069236678575 1.3628351269508192 3.6651785129795518 0.8755617256836258 0.2510858891864859 0.1821150615327996 0.7809063372136519 0.06884531991217208 0.6103009361820451 9.948933781359475e-06 5.002223459724997 2.3023433860287326 DLLSDLQDIS(ph)DSER ddPTM_PC-9_AZD4547_30min_R2 8 DLLSDLQDISDSER 14 0 P21127;P21127-8;A0A0D9SEN2;A0A0D9SER5;A0A0D9SEI3;P21127-9;P21127-2;P21127-3;P21127-6;P21127-10;P21127-5;E7ESP2;J3KS35;Q9UQ88-9;Q5QPR4;Q5QPR3;Q9UQ88-4;Q9UQ88-3;Q9UQ88-2;Q9UQ88 P21127;Q5QPR4 CDK11B;CDK11A Cyclin-dependent kinase 11B;Cyclin-dependent kinase 11A 1 DLLSDLQDIS(0.961)DS(0.039)ER;DLLSDLQDIS(0.994)DS(0.006)ER;DLLSDLQDIS(0.994)DS(0.006)ER;DLLSDLQDIS(1)DSER;DLLS(0.001)DLQDIS(0.89)DS(0.109)ER;DLLSDLQDIS(0.987)DS(0.013)ER;DLLSDLQDIS(0.99)DS(0.01)ER;DLLSDLQDIS(0.911)DS(0.089)ER 185.86 5.7897e-08 5134400.0 34044.600000000006 36919.06 45216.8 43464.00000000001 46724.200000000004 48430.7 41633.07 49219.2 38839.52 44640.700000000004 True False 44870.074628329385 48852.424153432425 44617.19568786774 33444.04631210601 40237.35134839951 45402.32067293072 45338.33257605652 41613.50358469853 40892.49773474837 43077.8426805716 1.041604496331152 1.1340499225014626 1.0357342176745168 0.7763630727773074 0.9340614302987561 1.0539599443174408 1.052474538064656 0.9660071395234121 0.9492698610274457 1.0 15.39465838170705 -5.529133408812114 24.999453251663986 0.9621157071105629 1.0870934627140854 0.3155079956577356 0.07601361699247831 186.7125993043506 746275.231394913 0.022335725148745777 0.03881318648303936 2.95710394862058e-06 5.529133408812114 0.12497775560352242 DLLSDLQDIS(ph)DSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DLLSDLQDISDSER 14 0 P21127;P21127-8;A0A0D9SEN2;A0A0D9SER5;A0A0D9SEI3;P21127-9;P21127-2;P21127-3;P21127-6;P21127-10;P21127-5;E7ESP2;J3KS35;Q9UQ88-9;Q5QPR4;Q5QPR3;Q9UQ88-4;Q9UQ88-3;Q9UQ88-2;Q9UQ88 P21127;Q5QPR4 CDK11B;CDK11A Cyclin-dependent kinase 11B;Cyclin-dependent kinase 11A 1 DLLSDLQDIS(0.994)DS(0.006)ER;DLLSDLQDIS(0.768)DS(0.232)ER;DLLSDLQDIS(0.976)DS(0.024)ER;DLLS(0.001)DLQDIS(0.99)DS(0.009)ER;DLLSDLQDIS(1)DSER;DLLSDLQDIS(0.843)DS(0.157)ER 170.35 3.1119e-05 3492500.0 37721.299999999996 37939.299999999996 38841.25 38175.4 44201.700000000004 35669.5 38335.9 27186.700000000004 30420.2 28297.1 True False 44106.77106036469 41705.66297190127 39767.372706260896 36036.556104316725 35540.69418955839 33798.92862743396 34704.4460241191 26473.07793168972 30865.037875635713 33427.14023027963 1.3194898144595402 1.2476587193696764 1.1896731946646766 1.0780627913743392 1.0632286801897646 1.011122351316717 1.0382116383585347 0.7919635885486057 0.9233526309162678 1.0 15.028732313862424 -5.724151946608106 0.5340654986031346 0.9080341209745679 1.3981776002018471 0.8238833465904322 0.06171871350621776 0.6949214668744765 0.3005913581190347 0.04420056443768688 0.19102854452106707 1.8873309131129914e-06 5.724151946608106 0.4901434792272792 DLLSDLQDIS(ph)DSER ddPTM_PC-9_Lapatinib_30min_R1 5 DLLSDLQDISDSER 14 0 P21127;P21127-8;A0A0D9SEN2;A0A0D9SER5;A0A0D9SEI3;P21127-9;P21127-2;P21127-3;P21127-6;P21127-10;P21127-5;E7ESP2;J3KS35;Q9UQ88-9;Q5QPR4;Q5QPR3;Q9UQ88-4;Q9UQ88-3;Q9UQ88-2;Q9UQ88 P21127;Q5QPR4 CDK11B;CDK11A Cyclin-dependent kinase 11B;Cyclin-dependent kinase 11A 1 DLLSDLQDIS(0.999)DS(0.001)ER;DLLSDLQDIS(1)DSER;DLLSDLQDIS(1)DSER;DLLSDLQDIS(0.753)DS(0.247)ER;DLLSDLQDIS(0.754)DS(0.246)ER 151.38 2.4678e-08 2295700.0 29979.660000000003 33108.9 38922.299999999996 33252.8 35782.94 33936.200000000004 33189.9 32838.200000000004 39042.100000000006 30417.55 True False 29552.144550803674 33032.23837625476 35722.25873842286 35698.32184008899 33678.2578211668 32484.827835146025 34908.31062257206 34363.982653742976 34644.76756646072 35675.182988662316 0.8283670068404537 0.9259164385156065 1.0013195657545892 1.0006485979745088 0.9440248093995721 0.9105721432590774 0.9785040383301196 0.9632461497019918 0.9711167445860316 1.0 15.122633209282965 -4.831518608691632 3.1396604058819944 0.9679761800880488 0.8152396209130347 0.718035272975289 0.027097549201332238 0.17722253798928705 2.7813998549441408 0.007401918020071697 0.06331433833781257 1.4739453838675038e-05 4.831518608691632 -0.15273655917501405 DLLSDLQDISDS(ph)ER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DLLSDLQDISDSER 14 0 P21127;P21127-8;A0A0D9SEN2;A0A0D9SER5;A0A0D9SEI3;P21127-9;P21127-2;P21127-3;P21127-6;P21127-10;P21127-5;E7ESP2;J3KS35;Q9UQ88-9;Q5QPR4;Q5QPR3;Q9UQ88-4;Q9UQ88-3;Q9UQ88-2;Q9UQ88 P21127;Q5QPR4 CDK11B;CDK11A Cyclin-dependent kinase 11B;Cyclin-dependent kinase 11A 1 DLLSDLQDIS(0.363)DS(0.637)ER;DLLSDLQDIS(0.226)DS(0.774)ER 107.82 0.0030528 0.0 6881.1 7473.9 7518.1 7666.1 7893.0 8026.799999999999 6306.4 7636.099999999999 5428.2 5311.7 True False 8045.934322079983 8215.859398715656 7697.360016553022 7236.593270831541 6346.423310374593 7605.86047762618 5709.0121376178595 7435.660466116737 5507.577155854521 6274.669162605936 1.282288215294274 1.3093693365824444 1.2267355962646846 1.1533027611970712 1.011435526863516 1.2121532276081606 0.9098507012355128 1.1850282896873288 0.8777478163593196 1.0 12.615323678378804 -5.631200733501865 0.47025990647213467 0.9920888760299768 1.4134631897335608 0.56891990362909 0.0965740042519799 1.6579391051077832 0.5011641215357858 0.07089596036115378 0.3591641934818286 2.3377564639164977e-06 5.631200733501865 0.421374313703584 DLLVSSGSNNSLPCGS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 DLLVSSGSNNSLPCGSPK 18 0 Q5THK1-2;Q5THK1-4;Q5THK1;Q5THK1-3 Q5THK1-2 PRR14L Protein PRR14L 1 DLLVS(0.178)S(0.232)GS(0.175)NNS(0.028)LPCGS(0.388)PK;DLLVSSGSNNSLPCGS(1)PK 90.45299999999999 0.0013377 15234300.0 157905.0 147282.0 160352.0 192303.0 168649.0 166478.0 151001.0 159930.0 146242.0 179488.0 True False 208115.50537196416 194888.02624351284 158225.62770786436 147970.51440173291 145234.9974436425 156068.1043426619 164439.796472302 135216.49332579257 153972.05356103973 173204.17975189514 1.201561680959879 1.125192397335206 0.9135208395924008 0.8543126073152046 0.8385190106363666 0.9010643078372609 0.9493985463159861 0.7806768492508801 0.8889626900551459 1.0 17.40211421994355 -5.21319827732996 2.7642033816712814 0.8789477734476102 1.1928333175869237 0.789549140505269 0.05692234698098589 0.11296661798795159 1.6609779503141011 0.014903449651359035 0.05057348278327987 6.120708867025683e-06 5.21319827732996 0.31388554413931347 DLLVSSGSNNSLPCGS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 DLLVSSGSNNSLPCGSPK 18 0 Q5THK1-2;Q5THK1-4;Q5THK1;Q5THK1-3 Q5THK1-2 PRR14L Protein PRR14L 1 DLLVSSGSNNSLPCGS(1)PK;DLLVSSGS(0.001)NNS(0.005)LPCGS(0.994)PK;DLLVSSGSNNSLPCGS(1)PK 220.16 6.6933e-28 19240100.0 190427.0 181385.0 150810.0 165526.0 174637.0 159263.0 154157.0 155311.0 147342.0 145896.0 True False 187711.4760599652 180965.0141767609 138410.98394343478 177699.33421854928 164365.19500955223 152451.692750186 162138.49516400578 162527.31605068114 130746.79237995537 171113.92920579994 1.0969970529646553 1.0575703276564528 0.8088820389190345 1.0384854993589039 0.9605599951589507 0.8909367779570491 0.9475470285589705 0.9498193209929063 0.7640920466662026 1.0 17.38459767890579 -5.085674428811892 7.577555844268215 0.9239981753542592 1.087477993278447 0.3948404368929652 0.07839994186778218 0.24067426636821262 18.61792879332599 0.019248075668541923 0.05190601300194906 8.20966755835248e-06 5.085674428811892 0.16347981792418786 DLMVGDEASELR ddPTM_PC-9_Lapatinib_30min_R1 1 DLMVGDEASELR 12 0 P61160 P61160 ACTR2 Actin-related protein 2 0 150.15 2.8208e-07 0.0 21961.0 19832.0 19143.0 18826.0 21025.0 20833.0 16367.0 16829.0 17752.0 15115.0 False True 21647.83211284583 19786.08022247446 17569.136434116925 20210.526841694973 19788.350836740417 19942.021154094968 17214.403175653955 17610.936777285002 15752.58282315272 17727.607610528485 1.2211366919013433 1.116116774308759 0.9910607691746605 1.1400594646336752 1.116244857822104 1.124913276072928 0.9710505531175151 0.9934186927076278 0.8885904499486557 1.0 14.113710233253062 -7.278122444996955 7.597701487670539 0.9623123575895172 1.1133416745907834 0.6194328195494907 0.059440557733097706 0.13340404435393757 43.99959634561569 0.025068951055042667 0.01743965443175697 5.270812351754994e-08 7.278122444996955 0.1510293170012662 DLNES(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DLNESPVK 8 0 Q96RL1-2;Q96RL1-3;Q96RL1;Q96RL1-4 Q96RL1-2 UIMC1 BRCA1-A complex subunit RAP80 1 DLNES(1)PVK;DLNES(1)PVK 86.911 0.012121 121006000.0 509990.0 676020.0 545820.0 593490.0 566000.0 472170.0 707260.0 501440.0 410560.0 391670.0 True False 596321.2342383597 743130.7979394633 558834.4188338782 560238.6794205406 455096.3630649971 447408.5739922197 640263.2126810246 488277.73131959676 416563.6632967901 462676.670541985 1.2888508805508214 1.606155756824633 1.207829256182839 1.210864335917932 0.9836164043713113 0.967000504840929 1.3838242847451385 1.0553325084396894 0.9003342718983917 1.0 18.819644830435507 -5.623138953383196 2.0762356707844853 1.0700561083848064 1.444635133788843 0.49468553298693296 0.1496125054094619 0.2719462081470273 2.353419511800699 0.044696018459132965 0.10057291146911795 2.3815573634317405e-06 5.623138953383196 0.37457902540403665 DLNES(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 2 DLNESPVK 8 0 Q96RL1-2;Q96RL1-3;Q96RL1;Q96RL1-4 Q96RL1-2 UIMC1 BRCA1-A complex subunit RAP80 1 DLNES(1)PVK;DLNES(1)PVK 106.67 0.0038224000000000005 170315000.0 917680.0 1097300.0 1054810.0 973720.0 1167560.0 1087980.0 1115960.0 1159480.0 986140.0 957870.0 True False 904593.7149180991 1094759.2692679125 968087.5934843477 1045330.6170346971 1098886.4163112787 1041449.6316052534 1173738.948365785 1213353.6736898436 875070.5286854338 1123436.5532184523 0.8052023163449631 0.9744736061254333 0.8617198636727134 0.9304758813837817 0.9781472867009342 0.9270213156423294 1.0447754659604274 1.080037559943901 0.7789229629198974 1.0 20.09948721903845 -6.044783539501383 3.3079547842479546 0.9738521335828368 0.8896789735893003 0.17017563565155114 0.08511300142594924 0.45529115262124953 10.05108744682908 0.025218300308030666 0.03568174898900121 9.020206095392586e-07 6.044783539501383 -0.08417315999353658 DLNYCFSGMSDHR ddPTM_PC-9_Lapatinib_30min_R1 2 DLNYCFSGMSDHR 13 0 P31943;G8JLB6;E9PCY7;P55795;H0YB39;H0YBD7;H0YBG7 P31943 HNRNPH1;HNRNPH2 Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;Heterogeneous nuclear ribonucleoprotein H2 0 ; 70.27199999999999 0.019398 12576700.0 29604.0 25437.0 66429.0 28979.0 44064.0 65937.0 33502.0 31569.0 74412.0 29184.0 False True 29181.841531291284 25378.102189344616 60967.46404335546 31110.212331110106 41472.24215315716 63117.0282166543 35236.569633455045 33035.81098830056 66030.93696690183 34228.41551476436 0.8525618581059866 0.7414337417517273 1.781194458652556 0.908900159801168 1.2116319592786347 1.8439950335833948 1.0294537185998522 0.9651574719855386 1.929126311395265 1.0 15.062906888902734 -5.225559139005581 24.980015645999657 1.3202684792604136 0.7969974872247041 0.25279631613583586 0.3684969122073939 814.5726279170881 567107.4495033564 0.09044099845645988 0.2393165822284628 5.948957427475061e-06 5.225559139005581 -0.5232709920357095 DLPAIQES(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DLPAIQESPTR 11 0 P49796-1;P49796-4;P49796-6;P49796 P49796-1 RGS3 Regulator of G-protein signaling 3 1 DLPAIQES(0.908)PT(0.092)R;DLPAIQES(0.976)PT(0.024)R 101.45 0.0037275 17569200.0 42431.0 48817.0 60725.0 47632.0 46359.0 53703.0 47745.0 40384.0 46154.0 35372.0 True False 49613.730249549604 53663.22913968639 62172.91430084494 44963.333465027565 37275.28674086604 50886.72014127157 43222.24795613422 39323.96279038492 46828.91493521048 41784.66359540208 1.187366990194197 1.2842805116083644 1.487936217528537 1.0760726447484252 0.8920805753469737 1.2178324715978106 1.0344045933850794 0.9411099529520219 1.1207201615561997 1.0 15.350685900448497 -5.89213251638228 7.628600390692107 1.0356879007805546 1.315058709308046 0.5824209988481898 0.10888203672566837 0.16170702067883508 10.386946404071313 0.030595868596591656 0.045586169713542665 1.2819393644986307e-06 5.89213251638228 0.2793708085274913 DLPAIQES(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 1 DLPAIQESPTR 11 0 P49796-1;P49796-4;P49796-6;P49796 P49796-1 RGS3 Regulator of G-protein signaling 3 1 DLPAIQES(0.965)PT(0.035)R 109.6 0.0020407 2870400.0 5865.9 10108.0 11848.0 9159.8 13786.0 8458.0 10510.0 8399.2 13605.0 7194.2 True False 5782.251190325689 10084.595547033674 10873.903174602585 9833.442248197045 12975.134584318834 8096.271056560992 11054.15637417505 8789.457494787104 12072.661632998686 8437.707884331065 0.6852869605812505 1.195181877030953 1.2887271429241545 1.1654162935004988 1.5377558410636414 0.959534410002019 1.3100899587555959 1.041687815610356 1.430798719095002 1.0 13.042635426601677 -4.762262768535645 5.523008424503955 1.2232942446334134 0.6597162906234024 0.44875968036956604 0.17593408253380918 0.1272254719810877 12.43238355857511 0.040300373847503256 0.2743578725465597 1.7287700557300236e-05 4.762262768535645 -0.563577954010011 DLPAIQES(ph)PTRDLPPCQDLPPSQVSLPAK ddPTM_PC-9_AZD4547_30min_R2 1 DLPAIQESPTRDLPPCQDLPPSQVSLPAK 29 1 P49796-1;P49796-4;P49796-6;P49796 P49796-1 RGS3 Regulator of G-protein signaling 3 1 DLPAIQES(0.5)PT(0.5)RDLPPCQDLPPSQVSLPAK 77.322 1.99e-06 6616200.0 22907.0 20639.0 29807.0 41967.0 37998.0 31003.0 22914.0 35461.0 24633.0 34504.0 True False 30190.949504800814 27310.15313235741 29411.73970445218 32292.156533686586 32722.633593223327 29064.377508953443 24953.301609700164 29981.317262714434 25935.050090733803 33296.02546220025 0.9067433450600729 0.8202226167613195 0.8833408581406283 0.9698501873848783 0.9827789695311271 0.8729083157973062 0.7494378462086633 0.9004473310711251 0.7789233018270277 1.0 15.023062352996266 -6.995538521595884 24.967777630974798 0.843515634654167 0.9108954469500106 0.09678792286315907 0.07641487687674993 248.64944355984088 1391505.493048722 0.02685852237414638 0.023595281636032188 1.0103258814032962e-07 6.995538521595884 0.06737981229584356 DLPAIQES(ph)PTRDLPPCQDLPPSQVSLPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DLPAIQESPTRDLPPCQDLPPSQVSLPAK 29 1 P49796-1;P49796-4;P49796-6;P49796 P49796-1 RGS3 Regulator of G-protein signaling 3 1 DLPAIQES(0.581)PT(0.419)RDLPPCQDLPPSQVSLPAK;DLPAIQES(0.958)PT(0.042)RDLPPCQDLPPSQVSLPAK;DLPAIQES(0.569)PT(0.431)RDLPPCQDLPPSQVSLPAK 99.226 1.1469e-06 11873200.0 33847.1 24934.0 36082.1 43816.9 50729.0 48116.0 45997.9 48611.0 43515.2 36202.8 True False 39576.74551930262 27409.282736934703 36942.434106126275 41361.981149306484 40789.016611173494 45592.712256622974 41640.64591604285 47335.01275761193 44151.52747732965 42766.0810587929 0.925423712892801 0.640911723925642 0.8638255643611455 0.9671679079606074 0.9537702684306887 1.066095165323756 0.9736839309357607 1.1068354075403324 1.0323959171435908 1.0 15.384179389053 -5.80459782008808 1.8449596757527533 1.0281826370451712 0.7769476265277436 0.6110809584695617 0.07681318087906286 0.20747826143534628 1.4418778366600238 0.02310831569876411 0.04517772296934517 1.5682026373837938e-06 5.80459782008808 -0.2512350105174276 DLPAIQES(ph)PTRDLPPCQDLPPSQVSLPAK ddPTM_PC-9_Lapatinib_30min_R1 1 DLPAIQESPTRDLPPCQDLPPSQVSLPAK 29 1 P49796-1;P49796-4;P49796-6;P49796 P49796-1 RGS3 Regulator of G-protein signaling 3 1 DLPAIQES(0.913)PT(0.087)RDLPPCQDLPPSQVSLPAK 84.478 2.8794e-08 5240700.0 10113.0 7463.3 8554.5 7142.0 7508.1 8891.3 6967.7 5969.4 8920.8 7012.0 True False 9968.786765502931 7446.019187393783 7851.182031324935 7667.24650501358 7066.488319492541 8511.039825632624 7328.453412782066 6246.760116366098 7916.045563811442 8224.014857097309 1.2121557339965026 0.905399530129482 0.9546653511392165 0.9322996903874463 0.8592504320920792 1.0349008329292613 0.8911041067073979 0.7595754901847188 0.962552439576384 1.0 13.005627155497532 -4.760114834849951 24.85217742769427 0.9165949674707946 1.212156120937427 0.5850036164330479 0.07312961092696839 21.84192428234782 409648.02840347117 0.018167252046878208 0.10993789602736186 1.737341385388912e-05 4.760114834849951 0.29556115346663236 DLPAIQESPT(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 DLPAIQESPTR 11 0 P49796-1;P49796-4;P49796-6;P49796 P49796-1 RGS3 Regulator of G-protein signaling 3 1 DLPAIQES(0.361)PT(0.639)R;DLPAIQES(0.233)PT(0.767)R 111.72 0.0043457 22573000.0 31616.0 33207.0 42043.0 46061.0 47565.0 45113.0 32556.0 46305.0 35832.0 37740.0 True False 41669.23034634751 43940.5133517221 41485.482349591795 35442.348085356054 40961.420781663976 42292.076978402656 35453.42093067112 39149.62623304454 37726.00636752217 36418.73408716198 1.1441702022541302 1.2065359890477805 1.1391247771079418 0.9731900071136708 1.124734887369502 1.1612725713415475 0.9734940496783729 1.0749859162964488 1.0358955991504661 1.0 15.152393154749573 -1.5228787452803443 0.19181115030533147 0.9994582363080837 1.8434334117045819 0.37914960584097535 0.06266084957869876 59.99277214809418 0.7055948923378638 0.12998009898082383 15.027434659862342 0.029999999999999537 1.5228787452803443 0.8439751753964981 DLPAIQESPT(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLPAIQESPTR 11 0 P49796-1;P49796-4;P49796-6;P49796 P49796-1 RGS3 Regulator of G-protein signaling 3 1 DLPAIQES(0.476)PT(0.524)R 115.12 0.0034016 4579600.0 14454.0 23228.0 19828.0 16462.0 18783.0 17684.0 18845.0 18168.0 17018.0 14494.0 True False 16900.776720487134 25533.922331495905 20300.774718108754 15539.687510524087 15102.6059848937 16756.619909097193 17059.865174015056 17691.109250587197 17266.856055107073 17121.647465559126 0.9870999128140979 1.4913239151114637 1.1856788173535617 0.9076046882627846 0.8820766818890058 0.9786803485356067 0.9963915685293516 1.0332597541313455 1.0084809940071502 1.0 14.063533905823538 -5.640619519784043 5.224012303494925 0.9720906733102115 1.261411990614639 0.4683865545716226 0.12156493987551086 0.15599116517861242 6.456130360170959 0.03194854354243005 0.05632152823380727 2.2876020666171245e-06 5.640619519784043 0.28932131730442756 DLPAIQESPT(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 DLPAIQESPTR 11 0 P49796-1;P49796-4;P49796-6;P49796 P49796-1 RGS3 Regulator of G-protein signaling 3 1 DLPAIQES(0.234)PT(0.766)R 115.12 0.0034016 11052000.0 15491.0 19761.0 20805.0 16277.0 22981.0 24230.0 23786.0 23149.0 22981.0 18961.0 True False 15270.095499298528 19715.244618612232 19094.493209622447 17474.064878480247 21629.30276238438 23193.739382888733 25017.522694208168 24224.58704957932 20392.637779341636 22238.383586055614 0.6866549198689742 0.8865412606235692 0.8586277476387936 0.7857614655697013 0.9726112816916626 1.0429597678777411 1.1249703737413357 1.089314201090098 0.9170018000826581 1.0 14.440764308027648 -6.423383593999278 3.1445639700978325 1.04482891766301 0.8137139941192796 0.6953623374731863 0.07188537927003293 0.1504091158710329 2.8401237745322434 0.02411628600805192 0.027233713769034804 3.772388445705277e-07 6.423383593999278 -0.2311149235437303 DLPAIQESPT(ph)RDLPPCQDLPPSQVSLPAK ddPTM_PC-9_AZD4547_30min_R2 1 DLPAIQESPTRDLPPCQDLPPSQVSLPAK 29 1 P49796-1;P49796-4;P49796-6;P49796 P49796-1 RGS3 Regulator of G-protein signaling 3 1 DLPAIQES(0.208)PT(0.792)RDLPPCQDLPPSQVSLPAK 85.185 4.0680000000000004e-08 4947700.0 16433.0 16188.0 24943.0 39009.0 32131.0 28283.0 22275.0 28636.0 22536.0 26710.0 True False 21658.352172366165 21420.45442640642 24612.239522533335 30016.07773304212 27670.165271431615 26514.459538939147 24257.431847607164 24210.964189816732 23727.206951844142 25774.891029891267 0.8402887968468564 0.8310589713673285 0.9548920883502631 1.1645472214890191 1.0735318042408943 1.028693370931819 0.9411264559557478 0.9393236294089142 0.920555083019656 1.0 14.653678707784238 -5.3703929394808485 4.198748632326031 1.0107192147643789 0.8359939916484824 0.4984057318451446 0.06847782422208812 0.1998368998751784 5.915312737477796 0.02076963276733291 0.04641514281028367 4.261937341895201e-06 5.3703929394808485 -0.17472522311589644 DLPAIQESPT(ph)RDLPPCQDLPPSQVSLPAK ddPTM_PC-9_Lapatinib_30min_R1 1 DLPAIQESPTRDLPPCQDLPPSQVSLPAK 29 1 P49796-1;P49796-4;P49796-6;P49796 P49796-1 RGS3 Regulator of G-protein signaling 3 1 DLPAIQES(0.103)PT(0.897)RDLPPCQDLPPSQVSLPAK 81.904 9.6509e-07 6259400.0 25434.0 20072.0 25039.0 21078.0 23338.0 25381.0 18588.0 18697.0 29439.0 16743.0 True False 25071.306495975645 20025.52451722 22980.390073335082 22628.14643414676 21965.304724273385 24295.51379600077 19550.39568821749 19565.73087675427 26123.269813586798 19637.00524135486 1.2767377809308893 1.0197850574000427 1.1702594051835955 1.1523216578102582 1.1185669329055943 1.2372311102120221 0.9955894724234746 0.9963704055824925 1.3303082365416947 1.0 14.261287306509496 -7.26080856772604 24.999998220195472 1.080264566623941 1.1538926739979978 0.11157109783294539 0.11167437512838473 149.9734100261842 5943893.893088807 0.042934304929627014 0.031383302659339134 5.485186927025288e-08 7.26080856772604 0.07362810737405678 DLPDGHAAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 DLPDGHAASPR 11 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 DLPDGHAAS(1)PR;DLPDGHAAS(1)PR;DLPDGHAAS(1)PR 140.01 0.00011688 53743500.0 89161.0 82649.0 121608.0 166638.0 141166.0 141162.0 90344.0 139747.0 104187.0 112993.0 True False 117512.343335991 109363.67296071567 119995.39846274431 128222.18363143585 121567.53760253062 132335.11782469088 98384.44098048152 118152.31221659163 109694.11211802394 109037.1494623923 1.0777275810619191 1.0029946078004908 1.1005001419642906 1.1759495205408006 1.1149185227412803 1.213670005839012 0.9023020270207542 1.0835968548255492 1.0060251268386122 1.0 16.734460226081552 -7.261304387836274 24.999999967010694 1.004947411619658 1.111438357992227 0.4206208071985278 0.06662483051967161 14.177597436452034 2626068.2079552943 0.027794273368328463 0.020161686381001263 5.478928238018399e-08 7.261304387836274 0.10649094637256895 DLPDGHAAS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DLPDGHAASPR 11 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 DLPDGHAAS(1)PR;DLPDGHAAS(1)PR;DLPDGHAAS(1)PR;DLPDGHAAS(1)PR 96.866 0.0042683 42378800.0 137424.0 133212.0 152057.0 195044.0 216510.0 203172.0 221844.0 189321.0 194757.0 186404.0 True False 160687.16895227772 146436.406992562 155682.61555938385 184116.31702117936 174086.41973003998 192517.3026561353 200829.33030852766 184351.52435218098 197604.95268095494 220197.5696267482 0.7297408832652186 0.6650228121989854 0.7070133236405735 0.8361414584787228 0.7905919217234315 0.8742934946215206 0.9120415391003125 0.8372096234516619 0.8973984273119386 1.0 17.74843902005668 -3.8570371769674945 0.16374298014843525 1.029672789653449 0.2243291324753381 0.8276492752507651 0.04065889908864112 11.717097308094798 0.2473261758694313 0.14256915141901272 2.0307783604849687 0.00013898336520085325 3.8570371769674945 -0.805343657178111 DLPDGHAAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 DLPDGHAASPR 11 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 DLPDGHAAS(1)PR;DLPDGHAAS(1)PR 146.67 0.00023624 40951000.0 41206.0 40390.0 42625.0 36834.0 48128.0 47138.0 52157.0 48420.0 55999.0 40710.0 True False 40618.39488374507 40296.47943655421 39120.53703725823 39542.89523462197 45297.2056632886 45122.01762404491 54857.43425383899 50669.7699659005 49691.8029243876 47746.66925733475 0.8507063532500826 0.8439641982014053 0.8193354142969589 0.8281812291764722 0.9486987546535539 0.9450296392583103 1.1489269326448757 1.0612210391642494 1.040738625276025 1.0 15.543112475765366 -6.718723385284455 1.6379876239848177 1.0647325009025863 0.8356015301053035 0.8266186328489986 0.04478871664902988 0.1383083603875122 0.7690041475597162 0.01872027906971102 0.01762031470524025 1.911070086815978e-07 6.718723385284455 -0.22913097079728284 DLPEHAVLK ddPTM_PC-9_AZD4547_30min_R2 2 DLPEHAVLK 9 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PRZ7;A0A1W2PQ74;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7;A0A1W2PQD4 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 ; 123.86 0.0012399000000000002 15165000.0 163876.0 162690.0 188756.0 256340.0 227390.0 198338.0 180397.0 221620.0 188091.0 191305.0 False True 215985.15916744858 215276.36092365088 186252.97210902037 197244.77341352057 195820.82353710855 185935.89350613818 196451.9835247044 187373.72132096603 198033.10626461302 184607.47017870992 1.1699697686034232 1.1661302801845008 1.0089135175771464 1.0684549938449244 1.0607416013422615 1.0071959348456607 1.0641605311774673 1.0149845027375015 1.0727253131896903 1.0 17.494101407549024 -5.252419210071191 24.927870608537194 1.0395380980481839 1.168050048132666 0.7928620034073375 0.02674102386942831 244.72831047195257 676319.741804175 0.006361565521625796 0.016326133253398486 5.592175467227495e-06 5.252419210071191 0.12851195008448224 DLPEHAVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DLPEHAVLK 9 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PRZ7;A0A1W2PQ74;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7;A0A1W2PQD4 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 ; 119.75 0.0014425 21838100.0 262230.0 271300.0 249200.0 305130.0 335640.0 293470.0 305720.0 283590.0 264240.0 233470.0 False True 306620.3597214151 298232.8710407634 255141.873096263 288034.55534480745 269873.7514119006 278079.91657559125 276759.98837887496 276146.06298844214 268104.010107033 275796.26285249676 1.111764012137481 1.0813521109974806 0.9251099723302623 1.0443743956706768 0.9785257734120797 1.008280219969173 1.0034943385976685 1.0012683280488557 0.9721089304622748 1.0 18.073243382337658 -5.085559956244702 6.6894679198744305 0.9942556565412067 1.1046088708564408 0.6795341958702238 0.02909418205981422 0.11251291709577939 7.2896124389522665 0.006857557029953133 0.01875840673817788 8.211831770946442e-06 5.085559956244702 0.11035321431523404 DLPEHAVLK ddPTM_PC-9_Lapatinib_30min_R1 2 DLPEHAVLK 9 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PRZ7;A0A1W2PQ74;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7;A0A1W2PQD4 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 ; 136.57 0.00083458 40013000.0 248978.0 234342.0 214034.0 218902.0 218104.0 201030.0 204133.0 187285.0 208995.0 189166.0 False True 245427.52806302617 233799.39549692906 196436.9507151321 235000.78331566486 205275.5515289622 192432.41552381858 214702.00790955982 195986.94481750714 185455.7822850836 221863.09105214852 1.106211614104569 1.0538003161687446 0.8853971599492406 1.0592153124758743 0.9252352455538112 0.8673475818408556 0.9677229632534711 0.8833688554868316 0.8359019132276155 1.0 17.75931015646043 -1.5228799715319734 0.4698946776972002 0.9065567916195308 6.375718678093056 0.46607310574434946 0.06465214955196225 80.85364462421323 0.9294400822336031 0.037685310420027936 429.44391926189627 0.02999991529365748 1.5228799715319734 5.469161886473525 DLPETIPWNPTPSMGGPGT(ph)PDSRPPFLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLPETIPWNPTPSMGGPGTPDSRPPFLSR 29 1 Q16512;Q16512-2;Q16512-3 Q16512 PKN1 Serine/threonine-protein kinase N1 1 DLPETIPWNPT(0.02)PS(0.017)MGGPGT(0.935)PDS(0.026)RPPFLS(0.001)R 60.138999999999996 0.012065000000000001 0.0 3399.7 4553.6 4497.5 4456.1 5464.7 3359.2 4526.5 4750.9 4208.8 2641.6 True False 3975.2020628642663 5005.651314306003 4604.7374568637315 4206.439163871125 4393.931263677183 3183.037638466372 4097.717150977935 4626.19390899464 4270.345737732674 3120.501169105907 1.273898597513825 1.6041177500152108 1.4756403562518423 1.3480011497885012 1.4080851201655347 1.0200405210482208 1.3131599473657694 1.4825163197487752 1.3684807363671723 1.0 11.607562036864694 -6.173818021266615 2.0728723927311625 1.2744669696799436 1.4598886330410208 0.20957681065261058 0.1629468304691552 0.560879643666941 4.7359965769376355 0.0552789088137533 0.07634372633440595 6.701653643000019e-07 6.173818021266615 0.18542166336107724 DLPHSVIDNDNYLNFSS(ph)LSSGALPYK ddPTM_PC-9_AZD4547_30min_R2 1 DLPHSVIDNDNYLNFSSLSSGALPYK 26 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 DLPHSVIDNDNYLNFS(0.019)S(0.508)LS(0.386)S(0.086)GALPYK 94.60600000000001 0.00030028 0.0 4786.5 4577.0 8376.1 11064.0 8687.7 8159.3 9832.1 8981.3 5903.7 8457.3 True False 6308.507434615141 6056.4257418867155 8265.027441153487 8513.365737096012 7481.562815617833 7649.097681153561 10707.137852698479 7593.4464547423195 6215.757529357573 8161.212501201775 0.7729865425861887 0.7420987679214185 1.0127205289577283 1.0431496221722423 0.9167219717065497 0.9372501549282288 1.3119543022708704 0.9304311649309647 0.7616218213215591 1.0 12.994567792192319 -5.261216983424512 24.999947791450182 0.9957520011124891 0.7575426349057756 0.3324639750993287 0.13105930041761896 21.81078632079385 2451410.5992704034 0.0351877534820803 0.08206353677920596 5.480031016690322e-06 5.261216983424512 -0.2382093662067135 DLPHSVIDNDNYLNFSS(ph)LSSGALPYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLPHSVIDNDNYLNFSSLSSGALPYK 26 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 DLPHSVIDNDNY(0.001)LNFS(0.149)S(0.431)LS(0.311)S(0.109)GALPYK 80.722 0.00028485 0.0 5942.4 6475.7 7570.7 6387.1 9653.1 7274.6 7385.5 7928.5 6546.7 4826.6 True False 6948.330952250088 7118.5646995896395 7751.2142000396325 6029.251494257591 7761.644350358161 6893.107169798602 6685.891973610415 7720.3852759401425 6642.433102360412 5701.624372655423 1.218658139875678 1.2485152009889953 1.3594747204347402 1.0574620669810244 1.3613040500497446 1.2089725171755341 1.172629330980741 1.354067678145644 1.1650071397577573 1.0 12.477157281223509 -8.53654614003061 22.627813252266115 0.999999995622913 1.245958876196506 0.4142630999297592 0.08994775935271863 573.7955803806907 949980.2915638259 0.08116772087800503 0.020957415415202556 2.907059093164415e-09 8.53654614003061 0.24595888057359294 DLPLLLFR ddPTM_PC-9_Lapatinib_30min_R1 1 DLPLLLFR 8 0 A0A286YFA2;A0A286YF22;A0A2C9F2M7;O43175 A0A286YFA2 PHGDH D-3-phosphoglycerate dehydrogenase 0 108.09 0.017506999999999998 1777700.0 7874.3 6654.1 7377.6 5472.0 7206.5 7391.1 7033.6 6654.6 7269.9 6644.2 False True 7762.011038030235 6638.692840276689 6771.042206359562 5874.429134056884 6782.627838524127 7074.9998824956165 7397.7653923308835 6963.797009811674 6451.087306559143 7792.641117159995 0.9960693584281316 0.851918205967137 0.8689020968063327 0.7538431509595559 0.8703888369231144 0.907907829466947 0.949327099902039 0.8936375877078258 0.827843501268569 1.0 12.927896660554886 -6.7346198739461105 5.205847347815268 0.9114339168090438 0.860493287407654 0.10264026113502289 0.06820956589753949 0.44783421661571293 31.65681950035539 0.023738627650218617 0.022880321129760576 1.8423838840527558e-07 6.7346198739461105 -0.05094062940138988 DLPPFGINS(ph)PQALKK ddPTM_PC-9_AZD4547_30min_R2 1 DLPPFGINSPQALKK 15 1 A0A2R8Y661;H0Y8H7;A0A2R8YGD3;Q9Y4G8 A0A2R8Y661 RAPGEF2 Rap guanine nucleotide exchange factor 2 1 DLPPFGINS(1)PQALKK 58.246 0.027256 5210200.0 15765.0 21651.0 26747.0 27097.0 21036.0 27218.0 28000.0 34333.0 24083.0 31044.0 True False 20777.94206762932 28649.26234161881 26392.317303820673 20850.205294476727 18115.514507791097 25516.054157297513 30491.9457568126 29027.623743853102 25355.978213581067 29957.159009058185 0.6935885362609541 0.9563410980646094 0.8810020100985008 0.69600075521755 0.6047140352098637 0.8517514678071505 1.0178517177677868 0.9689711809813468 0.8464079723285558 1.0 14.870613191667662 -7.004598030507974 24.981363485712333 0.9527333725094556 0.7742374323193053 0.43932403721349245 0.10196426555628847 218.02585029975648 1184551.2011253352 0.039622777455976366 0.034063767750282734 9.894684922833061e-08 7.004598030507974 -0.17849594019015025 DLPPFGINS(ph)PQALKK ddPTM_PC-9_Lapatinib_30min_R1 1 DLPPFGINSPQALKK 15 1 A0A2R8Y661;H0Y8H7;A0A2R8YGD3;Q9Y4G8 A0A2R8Y661 RAPGEF2 Rap guanine nucleotide exchange factor 2 1 DLPPFGINS(1)PQALKK 85.49600000000001 0.0026466 5430100.0 30444.0 33783.0 31209.0 29898.0 32595.0 28225.0 28979.0 33027.0 29422.0 27444.0 True False 30009.862977254146 33704.77753912133 28643.116490223867 32096.798656804247 30677.826184235633 27017.882545688593 30479.390824664002 34561.55499099122 26108.18453260474 32187.658833168647 0.9323406567963765 1.047133552453008 0.8898788395479011 0.9971771734988452 0.9530928093665152 0.8393863836361806 0.9469278577432816 1.0737517497040303 0.8111240605576711 1.0 14.974220025870823 -5.266029195760316 24.94523519594292 0.940869738155005 0.9897371011327526 0.06316780686237755 0.07799502545158045 1055.6835704374028 5737587.487268903 0.019627064144149615 0.04312499559875703 5.4196445522488485e-06 5.266029195760316 0.04886736297774763 DLPS(ph)PDSR ddPTM_PC-9_AZD4547_30min_R2 1 DLPSPDSR 8 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 DLPS(1)PDSR 106.88 0.003819 13832000.0 87064.0 96564.0 145140.0 147650.0 133760.0 153160.0 98787.0 166380.0 130960.0 144880.0 True False 114748.54095630076 127776.42458805954 143215.34876720875 113611.57366976018 115189.73286566536 143582.88098801114 107578.85162422329 140669.79403204756 137882.27823986099 139807.79529803988 0.8207592481641082 0.9139434916033683 1.0243731292801286 0.8126268884189537 0.8239149513809716 1.0270019685377598 0.7694767762762336 1.0061655985073656 0.9862273984503216 1.0 17.093085278099295 DLPS(ph)PDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLPSPDSR 8 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 DLPS(0.999)PDS(0.001)R 70.399 0.038245 10891000.0 130300.0 121010.0 122490.0 136070.0 178330.0 154640.0 157580.0 153190.0 151700.0 140960.0 True False 152357.21645769165 133023.07307277087 125410.62614591188 128446.43904489218 143387.5166526166 146530.4061718383 142652.88161959633 149168.92481822133 153918.32551179582 166514.9321612542 0.9149762996038571 0.79886573141651 0.7531494294125128 0.7713809048698633 0.8611090596593414 0.8799835802709708 0.8566972329031147 0.8958291180382858 0.9243514891669911 1.0 17.345292030646576 -8.107845827758924 0.5634530226432661 0.998972019039618 0.8095560269450337 0.6162435479213432 0.04430437697210829 0.5516439684465907 0.4148651570627841 0.048243817440901705 0.025264803792352446 7.801069952259513e-09 8.107845827758924 -0.18941599209458426 DLPTIPGVT(ph)SPSSDEPPMEASQSHLR ddPTM_PC-9_AZD4547_30min_R2 2 DLPTIPGVTSPSSDEPPMEASQSHLR 26 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 DLPT(0.015)IPGVT(0.752)S(0.099)PS(0.099)S(0.034)DEPPMEAS(0.001)QSHLR;DLPTIPGVT(0.436)S(0.436)PS(0.103)S(0.025)DEPPMEASQSHLR 101.41 2.0913e-09 12491500.0 15681.2 16590.8 25813.2 43337.0 40673.5 47416.0 33105.7 52079.9 41447.0 38801.0 True False 20667.495410777607 21953.451649223083 25470.900101954736 33346.324199975556 35026.68660071502 44451.070024337554 36052.04316576113 44032.14813204486 43637.80380427248 37442.588800105244 0.5519782705494849 0.5863230175249361 0.6802654655621232 0.8905987878669817 0.9354771591171752 1.1871793978148384 0.9628619259803904 1.1759910183326077 1.1654590455067526 1.0 15.192392566606344 -5.893935295669168 1.0438328556799072 1.106172156004585 0.5300525580872785 0.8865832958330412 0.07608055412734481 0.16810155435134413 0.3640451492825515 0.02927692069370294 0.07059790312345991 1.2766289960580858e-06 5.893935295669168 -0.5761195979173065 DLPTIPGVT(ph)SPSSDEPPMEASQSHLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLPTIPGVTSPSSDEPPMEASQSHLR 26 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 DLPTIPGVT(0.486)S(0.486)PS(0.021)S(0.008)DEPPMEASQSHLR 80.477 3.2337e-05 6587900.0 9538.9 16323.0 20561.0 15788.0 20806.0 18141.0 19385.0 11246.0 14244.0 14309.0 True False 11153.647368137184 17943.439565051143 21051.252218026737 14903.449545386617 16729.213657120694 17189.65402459468 17548.712464753626 10950.804416121946 14452.291552999477 16903.108430018332 0.6598577660620903 1.0615467349890084 1.2454071572209577 0.8816987483153981 0.9897122606994098 1.0169522425867819 1.038194397048815 0.6478574317534606 0.855007918385802 1.0 14.045000957666534 -7.7329091753863635 24.999034392535396 0.8135742430772799 0.9952086938881245 0.14961166075997434 0.16081946302169656 317.65381567349294 278338.17256657104 0.07500914245775486 0.04329637193027034 1.84965539955857e-08 7.7329091753863635 0.18163445081084462 DLPTIPGVT(ph)SPSSDEPPMEASQSHLR ddPTM_PC-9_Lapatinib_30min_R1 2 DLPTIPGVTSPSSDEPPMEASQSHLR 26 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 DLPT(0.032)IPGVT(0.456)S(0.456)PS(0.04)S(0.016)DEPPMEASQSHLR;DLPT(0.002)IPGVT(0.408)S(0.408)PS(0.143)S(0.04)DEPPMEASQSHLR 70.57 0.00024888 4633500.0 18840.8 18288.8 35253.0 23119.8 44748.0 41182.4 33073.1 44396.0 44757.0 31054.0 True False 18572.126737020437 18246.45340726053 32354.634420515285 24820.107217391876 42116.010617952896 39421.124752863245 34785.46329007887 46458.800235566254 39715.99534789581 36421.64252314597 0.5099200763726633 0.500978323414846 0.8883354011273352 0.6814658949447073 1.156345724693447 1.0823543921120828 0.9550767313136054 1.2755822367440366 1.090450418941328 1.0 15.152508365196535 -5.615620812725419 0.8202356071762771 1.1162257522272772 0.4089339068441575 0.757402408549071 0.1252483635290859 0.4478906551449772 0.4905586696312493 0.05356698616815682 0.23372023972639547 2.423143796817052e-06 5.615620812725419 -0.7072918453831196 DLPTIPGVTS(ph)PSSDEPPMEASQSHLR ddPTM_PC-9_AZD4547_30min_R2 1 DLPTIPGVTSPSSDEPPMEASQSHLR 26 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 DLPT(0.021)IPGVT(0.199)S(0.772)PS(0.006)S(0.002)DEPPMEASQSHLR 70.109 0.00018751 7680200.0 7842.2 12430.0 16667.0 25687.0 22737.0 24324.0 15797.0 33903.0 26114.0 19582.0 True False 10335.856472106734 16447.75441810179 16445.984689975656 19765.259010193895 19580.360019188356 22803.016434789668 17202.90239715602 28664.070363436094 27494.33272721238 18896.44014029693 0.5469737366068952 0.8704155013317412 0.8703218472829893 1.0459779124240547 1.0361930540257134 1.2067360976717465 0.9103779478797481 1.5169031918509113 1.4550006521376648 1.0 14.205826853378342 -4.619619816958797 0.417089955337445 1.2823309021995455 0.016316441372887323 0.5793873531567748 0.17716041328680093 4.550019614646289 0.5616061346849658 0.14106021339601268 2.959761911961242 2.4009337858995074e-05 4.619619816958797 -1.2660144608266581 DLPTIPGVTSPSS(ph)DEPPMEASQSHLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLPTIPGVTSPSSDEPPMEASQSHLR 26 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 DLPTIPGVT(0.062)S(0.278)PS(0.278)S(0.382)DEPPMEASQSHLR 81.477 1.6249e-05 6033700.0 12957.0 24960.0 28018.0 20226.0 29601.0 24894.0 25927.0 17640.0 19426.0 21085.0 True False 15150.364187584873 27437.863845106676 28686.055378856712 19092.80279357674 23800.89654255648 23588.514816617604 23471.00686477519 17176.96869112495 19710.068499618654 24907.543591231843 0.6082640840150222 1.1015885105091445 1.1517015025502157 0.766546999050438 0.9555698037977163 0.9470430004555498 0.9423252348753349 0.6896291731141133 0.7913292785145282 1.0 14.604295128005294 -7.7191811854867405 24.940536447576985 0.8053592254603624 0.9362142386749025 0.06335700502245711 0.16190314078157095 289.81285198066143 171045.55178178562 0.07508163086107492 0.04334789896033471 1.9090566435178972e-08 7.7191811854867405 0.13085501321454007 DLPTIPGVTSPSSDEPPMEAS(ph)QSHLRNSPEDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLPTIPGVTSPSSDEPPMEASQSHLRNSPEDK 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 DLPTIPGVTSPS(0.003)S(0.007)DEPPMEAS(0.427)QS(0.135)HLRNS(0.427)PEDK 41.36600000000001 0.02412 6109000.0 12966.0 16518.0 20955.0 25395.0 23826.0 19068.0 23504.0 14833.0 17213.0 17190.0 True False 15160.887709826788 18157.79787634102 21454.646672280043 23972.200481700842 19157.4663363721 18068.040512704447 21277.530965776084 14443.649466862598 17464.707561203333 20306.410924034873 0.7466059741695765 0.894190408352727 1.0565454797768377 1.1805237553489625 0.9434196130492528 0.8897702592691519 1.047823322662686 0.7112851956407003 0.8600588073657038 1.0 14.309647651204221 -7.747236697717046 24.991531824511384 0.839253942728279 0.9708109891126802 0.125962938023918 0.1278144906061989 410.9644697746487 723150.1451555818 0.06327182176831468 0.03630582282157342 1.7896302099537244e-08 7.747236697717046 0.13155704638440113 DLPTIPGVTSPSSDEPPMEAS(ph)QSHLRNSPEDK ddPTM_PC-9_Lapatinib_30min_R1 1 DLPTIPGVTSPSSDEPPMEASQSHLRNSPEDK 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 DLPTIPGVTSPS(0.001)S(0.001)DEPPMEAS(0.798)QS(0.14)HLRNS(0.06)PEDK 66.925 2.8599000000000002e-05 3932100.0 16254.0 14898.0 22202.0 19823.0 24278.0 23535.0 18456.0 21489.0 22229.0 12162.0 True False 16022.21497938145 14863.504596330386 20376.63726219841 21280.849547589492 22850.01577238448 22528.462912764593 19411.561374098448 22487.45738945139 19725.3359382527 14264.185495153662 1.1232478002214068 1.0420156553194253 1.4285174059971026 1.491907796264973 1.6019152148678872 1.5793725425415117 1.360860133282313 1.5764978236641434 1.3828575031469197 1.0 13.80010974892605 -5.292307102457056 6.270131660437685 1.4609899391073486 1.0818352265175653 0.39302923817781665 0.16761797874418324 0.14192979914899445 19.143611898609887 0.04103656649792457 0.09020437160485173 5.10144134414176e-06 5.292307102457056 -0.3791547125897834 DLPTIPGVTSPSSDEPPMEAS(ph)QSHLRNSPEDKR ddPTM_PC-9_AZD4547_30min_R2 1 DLPTIPGVTSPSSDEPPMEASQSHLRNSPEDKR 33 2 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 DLPTIPGVTSPS(0.001)S(0.001)DEPPMEAS(0.388)QS(0.329)HLRNS(0.281)PEDKR 54.324 0.0034402 9581600.0 27263.0 29533.0 66514.0 81999.0 77795.0 78052.0 48628.0 79363.0 60044.0 70628.0 True False 35932.06689437221 39078.964700707955 65631.98090052437 63095.397421921196 66994.50708944692 73171.3961013075 52955.797795081555 67099.2719303123 63217.80325774447 68155.33521749015 0.5272084243986119 0.5733808597082424 0.9629764227714013 0.9257587424458817 0.9829679052367813 1.0735974794608614 0.7769868290735358 0.9845050532902838 0.927554725628015 1.0 16.05653897554607 -5.242842163143171 5.609735328360553 0.9523035160780299 0.5437230151852008 0.8343281418472688 0.07204623069350338 0.06108347857670394 6.7901300629837875 0.018428171376171365 0.0470770498740978 5.716863684953008e-06 5.242842163143171 -0.40858050089282905 DLPTIPGVTSPSSDEPPMEAS(ph)QSHLRNSPEDKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLPTIPGVTSPSSDEPPMEASQSHLRNSPEDKR 33 2 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 DLPTIPGVT(0.001)S(0.001)PS(0.015)S(0.015)DEPPMEAS(0.323)QS(0.323)HLRNS(0.323)PEDKR 48.422 0.025144999999999997 13212000.0 29599.0 38314.0 60487.0 78994.0 73101.0 63661.0 60582.0 43848.0 48761.0 44919.0 True False 34609.52609310216 42117.560711595244 61929.23947822494 74568.22228200335 58777.383809919214 60322.50509121449 54843.23438430247 42697.03646079629 49474.03737825106 53062.45912139166 0.6522412769058726 0.793735560111196 1.1671008186135632 1.4052914907583285 1.107701843886531 1.1368207597241946 1.0335599836946288 0.804656195128796 0.9323736252982298 1.0 15.695403916782602 -9.338134993847834 14.22253347040553 1.0000051374715473 1.0161562151256571 0.0 0.20763207184162485 0.0 0.0 0.223008765965827 0.05408757044210317 4.5905530028560175e-10 9.338134993847834 0.016151077654109836 DLPTIPGVTSPSSDEPPMEAS(ph)QSHLRNSPEDKR ddPTM_PC-9_Lapatinib_30min_R1 1 DLPTIPGVTSPSSDEPPMEASQSHLRNSPEDKR 33 2 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 DLPTIPGVTSPS(0.001)S(0.001)DEPPMEAS(0.348)QS(0.348)HLRNS(0.3)PEDKR 47.428999999999995 0.028888 6928500.0 15182.0 11031.0 22775.0 13449.0 21342.0 23272.0 14473.0 16588.0 20930.0 11675.0 True False 14965.501895962183 11005.458397242614 20902.527414042357 14438.084324548814 20086.705519986383 22276.710809681663 15222.341123067128 17358.73903747124 18572.64299732912 13693.008194040363 1.0929301789562684 0.8037283145738964 1.52651098413421 1.0544128886764803 1.4669315343526022 1.6268675585381744 1.1116871404263367 1.267708219515002 1.3563595912702755 1.0 13.74115180422238 -5.254771173594532 24.991524055560703 1.3128228969871394 0.9483292413333089 0.32129359733039353 0.20466443837678477 572.4761649181911 2145548.057102234 0.050708570806884 0.1277986266379336 5.561972361038457e-06 5.254771173594532 -0.3644936556538305 DLPTIPGVTSPSSDEPPMEASQSHLRNS(ph)PEDK ddPTM_PC-9_AZD4547_30min_R2 1 DLPTIPGVTSPSSDEPPMEASQSHLRNSPEDK 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 DLPTIPGVT(0.002)SPS(0.016)S(0.016)DEPPMEAS(0.174)QS(0.07)HLRNS(0.722)PEDK 59.372 0.00039294 8879400.0 10674.0 11531.0 24220.0 34717.0 28454.0 30584.0 18097.0 31241.0 20202.0 25470.0 True False 14068.109967007631 15258.170249004965 23898.826974933127 26713.532022303156 24503.653251791577 28671.577645190227 19707.597941465632 26413.42129676156 21269.83647679958 24578.303052464627 0.5723792215019063 0.6207983609134857 0.9723546383132677 1.0868745480630086 0.9969627764571987 1.1665401628415164 0.8018290725522412 1.074664155632702 0.8653907648301503 1.0 14.585097691423321 -5.256522964759798 4.25369581540029 1.0029640464228475 0.5844862250204004 0.7220643632499987 0.099295612134414 0.09440587389945469 4.333053492127307 0.024990523001098223 0.06483001907212614 5.539582507860224e-06 5.256522964759798 -0.41847782140244716 DLPTIPGVTSPSSDEPPMEASQSHLRNS(ph)PEDK ddPTM_PC-9_Lapatinib_30min_R1 1 DLPTIPGVTSPSSDEPPMEASQSHLRNSPEDK 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 DLPTIPGVTSPSSDEPPMEAS(0.211)QS(0.211)HLRNS(0.579)PEDK 83.788 7.6863e-09 6112000.0 50443.0 44294.0 73132.0 46857.0 69731.0 69931.0 55013.0 58427.0 62620.0 41379.0 True False 49723.67356988675 44191.43996441524 67119.36925768359 50303.0200903698 65629.55967642073 66940.214147123 57861.30395932366 61141.73171825009 55567.0761821667 48531.30501594827 1.0245690601879889 0.9105759663766126 1.3830118360845014 1.0365066439865838 1.3523139271621414 1.3793202990343085 1.192247023654307 1.2598410798588213 1.144973871275589 1.0 15.566628034515006 -6.248533638882902 24.919098027302912 1.2408748540910504 1.0969698810508888 0.1491039986208299 0.15066130056360427 1387.6794913802769 2679404.0315095037 0.04470869263427208 0.057345385031310085 5.642432354081987e-07 6.248533638882902 -0.1439049730401616 DLPTIPGVTSPSSDEPPMEASQSHLRNS(ph)PEDKR ddPTM_PC-9_AZD4547_30min_R2 2 DLPTIPGVTSPSSDEPPMEASQSHLRNSPEDKR 33 2 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 DLPTIPGVT(0.001)S(0.001)PS(0.001)S(0.001)DEPPMEAS(0.113)QS(0.113)HLRNS(0.771)PEDKR;DLPTIPGVTSPSSDEPPMEAS(0.291)QS(0.216)HLRNS(0.493)PEDKR 57.951 0.0022033 30657000.0 40512.0 34294.0 77995.0 112598.0 94617.0 109328.0 66263.0 104312.0 72474.0 92630.0 True False 53393.97329805259 45378.864844278556 76960.73533897228 86640.27072175861 81481.06275830326 102491.70287710446 72160.27863155965 88192.97725129784 76304.82768139661 89387.05189437767 0.597334537457891 0.5076670936401341 0.8609830362221961 0.9692709277864457 0.9115533070112173 1.1466056962949356 0.8072788743142164 0.986641525615021 0.853645198765036 1.0 16.447778245402596 -5.368922104799728 3.7319223746376875 0.9513728066574464 0.5510865693425772 0.7571124120341461 0.08927866487499729 0.10165840760605256 2.526904327315944 0.023039836082144802 0.05327416485583703 4.2763958084843015e-06 5.368922104799728 -0.40028623731486923 DLPTIPGVTSPSSDEPPMEASQSHLRNS(ph)PEDKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLPTIPGVTSPSSDEPPMEASQSHLRNSPEDKR 33 2 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 DLPTIPGVTSPS(0.001)S(0.001)DEPPMEAS(0.322)QS(0.296)HLRNS(0.381)PEDKR 55.406000000000006 0.003071 12697000.0 41034.0 58670.0 90162.0 110950.0 110620.0 89626.0 79376.0 63836.0 74616.0 58590.0 True False 47980.24574155733 64494.369863477885 92311.8040212893 104733.83120475318 88944.80509231446 84925.85478244426 71856.9306475257 62160.372639832894 75707.11784039659 69211.9032018153 0.6932369075540593 0.9318392773482687 1.3337561857259856 1.513234376742384 1.2851084998047215 1.2270411714414007 1.038216366309098 0.8981167944273861 1.093845340730508 1.0 16.07873255633411 -7.387356269389912 4.881272241871021 0.992335254500787 1.181995321343528 0.10992516998815305 0.21599052632304222 0.5349887782667186 18.96662978363288 0.10494433894162632 0.06916828558612077 4.098677338997303e-08 7.387356269389912 0.18966006684274095 DLPTIPGVTSPSSDEPPMEASQSHLRNS(ph)PEDKR ddPTM_PC-9_Lapatinib_30min_R1 1 DLPTIPGVTSPSSDEPPMEASQSHLRNSPEDKR 33 2 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 DLPTIPGVTSPS(0.008)S(0.008)DEPPMEAS(0.089)QS(0.239)HLRNS(0.655)PEDKR 66.432 8.3958e-05 22383000.0 37376.0 34982.0 64624.0 37714.0 50316.0 55490.0 32205.0 43074.0 49152.0 35085.0 True False 36843.01138608106 34901.00132828765 59310.86417585392 40487.61337021589 47356.51180506209 53116.82205350789 33872.41731972476 45075.37528936801 43615.984166494054 41149.395502176114 0.8953475728247984 0.8481534394944387 1.4413544464515249 0.9839175734203622 1.150843438333322 1.2908287328473367 0.823157106109456 1.0954079577422777 1.0599422818784179 1.0 15.328583616698939 -10.570613375020596 14.655352302211528 1.000000012434941 1.0706035394618978 0.010454825791426758 0.1849501632036334 0.0 0.0 0.17778146788895358 0.04311833879181081 2.687736102824049e-11 10.570613375020596 0.07060352702695671 DLQEQDADAGS(ph)ER ddPTM_PC-9_AZD4547_30min_R2 2 DLQEQDADAGSER 13 0 A0A087WW12;A0A087WZ11;Q6P158-3;Q6P158-2;Q6P158 A0A087WW12 DHX57 Putative ATP-dependent RNA helicase DHX57 1 DLQEQDADAGS(1)ER;DLQEQDADAGS(1)ER 149.99 0.00012497 20790500.0 43861.0 44498.0 52946.0 48650.0 60053.0 65644.0 57381.0 56656.0 45514.0 45853.0 True False 57807.885634525184 58881.10829418289 52243.90144569819 37434.49413500729 51715.677540234756 61539.27030280105 62487.7978382737 47901.117025361666 47919.77712132743 44247.700426567004 1.306460789537809 1.3307156694369084 1.1807144991049103 0.8460212344172138 1.168776615319513 1.3907902492002029 1.4122270137400192 1.0825673778201836 1.082989096819948 1.0 15.433314859165545 -7.971179822946505 24.957603489145082 1.055255536100138 1.2256761522877673 0.22396606539143948 0.15259182008780073 357.31310800299667 309424.63320550893 0.09388281099355884 0.045098740687711546 1.068612320515341e-08 7.971179822946505 0.17042061618762938 DLQEQDADAGS(ph)ER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLQEQDADAGSER 13 0 A0A087WW12;A0A087WZ11;Q6P158-3;Q6P158-2;Q6P158 A0A087WW12 DHX57 Putative ATP-dependent RNA helicase DHX57 1 DLQEQDADAGS(1)ER 124.5 0.00015299 7235500.0 11982.0 11809.0 16764.0 16267.0 15159.0 12713.0 17424.0 12362.0 11029.0 13532.0 True False 14010.315944712662 12981.319477037856 17163.717337824044 15355.612728325557 12188.702769792011 12046.307900042564 15773.472581164155 12037.51059862168 11190.278260181918 15985.244480746946 0.8764530290160442 0.8120813849718034 1.0737225419665293 0.9606116907889815 0.7624971131641064 0.7535892187668107 0.9867520387418626 0.7530388798945165 0.7000379802548399 1.0 13.964453188632787 -6.252884942212426 24.80313502559709 0.818056291070674 0.9324578509437448 0.171449661909588 0.11195337014565337 1005.1683802922554 2914430.475402612 0.03381647692575389 0.042927983150571766 5.586181700397412e-07 6.252884942212426 0.11440155987307077 DLQEQDADAGS(ph)ER ddPTM_PC-9_Lapatinib_30min_R1 2 DLQEQDADAGSER 13 0 A0A087WW12;A0A087WZ11;Q6P158-3;Q6P158-2;Q6P158 A0A087WW12 DHX57 Putative ATP-dependent RNA helicase DHX57 1 DLQEQDADAGS(1)ER;DLQEQDADAGS(1)ER 158.65 0.00010163 37697000.0 32343.0 30361.0 36553.0 30992.0 30235.0 31154.0 30197.0 36641.0 33419.0 27169.0 True False 31881.7828890202 30290.7009698743 33547.75343866039 33271.255066281235 28456.6367442971 29821.61604352107 31760.452904944243 38343.47462454689 29655.000302328783 31865.125449583098 1.0005227482773749 0.9505909844227712 1.052804687423545 1.0441275405905088 0.8930338839971335 0.9358700341759124 0.9967151378454647 1.2033053089721495 0.9306412538450173 1.0 14.959690720046412 -7.545376425956364 24.99992188329138 1.0601860057074417 0.9793329478249684 0.11301875266792172 0.07816356577153055 410.47428888904875 456122.42924121936 0.03598298248724601 0.020776689585134196 2.8485482100690795e-08 7.545376425956364 -0.08085305788247332 DLQGRDEQSEEK ddPTM_PC-9_AZD4547_30min_R2 1 DLQGRDEQSEEK 12 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 145.09 5.7275e-06 0.0 27809.0 15664.0 33578.0 62673.0 42150.0 25760.0 19624.0 24887.0 20167.0 33457.0 False True 36651.68353686671 20727.0816737849 33132.73378052455 48224.70813819762 36298.20006196017 24149.2231277825 21370.497983274654 21041.285996367114 21232.986448253494 32285.680613518245 1.1352303200794345 0.6419899249423389 1.0262361874028958 1.4936872081304549 1.1242817054555714 0.7479855672508589 0.6619187694722679 0.651721927384643 0.65765955819321 1.0 14.978606820368569 -6.79092704806381 7.2483847386710565 0.7153535501118914 1.0793479040717757 0.38161006854527235 0.21518416499049295 0.21004203377844569 37.436648875614004 0.08130192715620244 0.07299825875527806 1.618351862387264e-07 6.79092704806381 0.36399435395988433 DLQGRDEQSEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DLQGRDEQSEEK 12 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 97.779 0.0050093 12832600.0 37234.0 18501.2 42282.0 54901.0 60771.0 67308.0 46861.0 66418.0 57244.0 34954.0 False True 43536.98079497841 20337.87686582883 43290.16323537795 51825.07496144351 48863.35879827365 63778.249991037825 42421.986835740005 64674.59787568798 58081.085204991745 41290.88350428826 1.0543969297837108 0.49255126409965644 1.0484193982161234 1.2551214835609228 1.1833933946508788 1.5446085086654575 1.0273935366709768 1.5663166390947099 1.4066321733939102 1.0 15.333535667853283 -5.576027495636926 3.2743697312399074 1.3037123848115257 0.7681697853959661 0.4560334218115577 0.2207292976777808 0.18545821060414663 4.040245795779097 0.058426586779912054 0.11573044509907558 2.654437501446877e-06 5.576027495636926 -0.5355425994155596 DLQGRDEQSEEK ddPTM_PC-9_Lapatinib_30min_R1 1 DLQGRDEQSEEK 12 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 98.902 0.0045543 6196900.0 38065.0 15853.0 32936.0 27540.0 18176.0 22754.0 14387.0 12618.0 21185.0 15612.0 False True 37522.18611973393 15816.293352505414 30228.12921663662 29565.383470746838 17106.9234153909 21780.864462164678 15131.888463868347 13204.278344273698 18798.922212060083 18310.513398317624 2.0492154044780353 0.8637820801878019 1.6508619151778665 1.6146670946683186 0.9342678188893758 1.1895277859421414 0.8264043795330539 0.7211309730663757 1.0266736821146334 1.0 14.160384622176945 -6.268120679943685 24.28679748954994 0.9415538151192058 1.5035873992250852 0.4904759713798661 0.2958277265517176 321.138020305616 1167347.6388111243 0.08857754968619612 0.1028098304030143 5.393607263752789e-07 6.268120679943685 0.5620335841058794 DLQS(ph)PDFTTGFHSDK ddPTM_PC-9_AZD4547_30min_R2 2 DLQSPDFTTGFHSDK 15 0 E9PDR5;E7EPI0;Q9P2D0-2;Q9P2D0 E9PDR5 IBTK Inhibitor of Bruton tyrosine kinase 1 DLQS(0.956)PDFT(0.021)T(0.021)GFHS(0.002)DK;DLQS(0.989)PDFT(0.008)T(0.002)GFHS(0.002)DK 128.82 0.00027067 0.0 15774.3 17367.1 20390.0 19386.1 23444.0 24995.0 21987.9 30049.0 22736.0 18501.699999999997 True False 20790.19927417729 22980.675442849184 20119.615277410685 14916.93415725931 20189.205272896677 23432.05869871599 23944.78050379357 25405.617507326548 23937.778543536057 17853.961114479192 1.164458639787048 1.287147165578418 1.1268992437254775 0.835497179679751 1.1307969779615825 1.31242913258689 1.3411466704929051 1.4229681214396237 1.3407544908408597 1.0 14.12395656843876 -6.737481858596521 5.551512399039738 1.3142562062758594 1.102997968013247 0.2441074308384672 0.14902353401086674 0.22861220855417289 20.093108641930375 0.05244357271258299 0.050564449887143655 1.830282559506497e-07 6.737481858596521 -0.21125823826261247 DLQS(ph)PDFTTGFHSDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DLQSPDFTTGFHSDK 15 0 E9PDR5;E7EPI0;Q9P2D0-2;Q9P2D0 E9PDR5 IBTK Inhibitor of Bruton tyrosine kinase 1 DLQS(0.994)PDFT(0.006)TGFHSDK;DLQS(0.996)PDFT(0.004)TGFHSDK 96.455 0.0052393 5368600.0 102367.0 139321.0 110304.0 124474.0 133334.0 97941.0 138034.0 113204.0 108452.0 76942.0 True False 119695.71125958947 153151.8681395877 112934.06569024934 117500.12533015298 107208.15984612764 92804.80154472342 124958.42024038192 110232.51494955241 110037.90532897369 90890.975527463 1.3169152444999672 1.6850063193931983 1.242522319018635 1.2927589856778459 1.1795248012684643 1.0210562820583013 1.3748165812416144 1.212799337996381 1.2106582055082618 1.0 16.471849437356028 -5.407145700668618 6.528306449734012 1.1996590155293252 1.499420468531708 0.46144280653056446 0.13408956700372524 0.1968340560804309 9.848936408358064 0.03369075918854289 0.07083331683389103 3.916104743786897e-06 5.407145700668618 0.2997614530023829 DLQS(ph)PDFTTGFHSDKIEAK ddPTM_PC-9_AZD4547_30min_R2 3 DLQSPDFTTGFHSDKIEAK 19 1 E9PDR5;E7EPI0;Q9P2D0-2;Q9P2D0 E9PDR5 IBTK Inhibitor of Bruton tyrosine kinase 1 DLQS(0.603)PDFT(0.284)T(0.114)GFHSDKIEAK;DLQS(1)PDFTTGFHSDKIEAK;DLQS(0.999)PDFT(0.001)TGFHSDKIEAK 109.91 7.3469e-05 27744700.0 93203.0 80394.0 113450.0 155543.0 133954.0 122111.0 104542.0 125237.0 101614.0 124546.0 True False 122839.61525716826 106379.78830964398 111945.57887308682 119684.96446539462 115356.79931434912 114475.3798663298 113846.03547531081 105884.49930996228 106985.10859090748 120185.68244885208 1.0220819381663504 0.8851286288191313 0.9314385590041306 0.9958337967280707 0.959821477599397 0.95248766353719 0.9472512295610648 0.8810075971821684 0.8901651711836606 1.0 16.87490551449305 -7.567873152913104 14.412882479953513 0.9141646724773113 0.9546810264234075 0.08775827807694003 0.0454846012841352 4.0484539728985975 1293.111021469225 0.020833304376725315 0.012027703170100025 2.7047482413701157e-08 7.567873152913104 0.040516353946096206 DLQS(ph)PDFTTGFHSDKIEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLQSPDFTTGFHSDKIEAK 19 1 E9PDR5;E7EPI0;Q9P2D0-2;Q9P2D0 E9PDR5 IBTK Inhibitor of Bruton tyrosine kinase 1 DLQS(0.66)PDFT(0.32)T(0.02)GFHSDKIEAK 46.971000000000004 0.034725 8232400.0 58540.0 60854.0 55204.0 70227.0 83799.0 71939.0 78184.0 63209.0 70916.0 62903.0 True False 68449.66578229675 66895.18294992475 56520.27272233587 66292.40886900605 67379.18750615485 68166.39219862827 70777.84551685813 61549.83072547143 71953.01234010891 74306.81596012588 0.9211761383912324 0.9002563504513729 0.7606337587209425 0.8921443882695703 0.9067699461421076 0.9173639230512494 0.9525081192395399 0.8283201201690564 0.9683231801873995 1.0 16.18120693083641 -6.148843898978543 3.710239432533358 0.9211121357898435 0.8602578434836574 0.2059148849573964 0.058174200162555485 0.4233603097867847 10.514179271309182 0.017606975518366704 0.023329370034271265 7.098328615185405e-07 6.148843898978543 -0.06085429230618611 DLQS(ph)PDFTTGFHSDKIEAK ddPTM_PC-9_Lapatinib_30min_R1 1 DLQSPDFTTGFHSDKIEAK 19 1 E9PDR5;E7EPI0;Q9P2D0-2;Q9P2D0 E9PDR5 IBTK Inhibitor of Bruton tyrosine kinase 1 DLQS(1)PDFTTGFHSDKIEAK 92.792 0.00036117 9110100.0 64305.0 51254.0 57122.0 46940.0 51980.0 50741.0 44432.0 47354.0 49197.0 43366.0 True False 63387.9989079073 51135.324512036364 52425.64965729651 50392.12418724968 48922.638596612 48570.925713048186 46732.471552554314 49554.239714276155 43655.91579262305 50861.75531843722 1.2462802062383669 1.005378681720408 1.0307479427138917 0.9907665174304887 0.9618747581619091 0.9549596825542783 0.9188135812452769 0.9742927550184824 0.8583249932940855 1.0 15.634293632090754 -1.5228787465499705 0.760928628982508 0.9458335154019047 55.12145564203824 0.7996881031119907 0.0429698597250237 163.7646866978782 0.6750157200803011 0.015156656550687786 15228.62103464892 0.029999999912296866 1.5228787465499705 54.175622126636334 DLQSNVEHLTEK ddPTM_PC-9_Lapatinib_30min_R1 1 DLQSNVEHLTEK 12 0 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 0 145.52 9.3257e-05 4514800.0 34789.0 34967.0 40280.0 38722.0 44460.0 41863.0 37765.0 45628.0 50054.0 34853.0 False True 34292.90248047873 34886.03605986608 36968.33388529646 41569.74505280532 41844.95021172312 40072.61707741934 39720.28691443584 47748.043453203354 44416.39142801295 40877.29461129669 0.8389229964108652 0.8534330951105827 0.9043733015315557 1.0169397326338048 1.0236722026158505 0.9803148045503243 0.9716955902326007 1.1680822791048382 1.0865785480758847 1.0 15.319012096861647 -5.338978853705595 0.5564359700046078 1.0679238484337035 0.7402106913704276 0.6797621165632218 0.054255903589662494 1.4213030332300844 0.5159832566827337 0.035845369576820586 0.27936347680798546 4.581641947094152e-06 5.338978853705595 -0.32771315706327586 DLQSPDFT(ph)TGFHSDK ddPTM_PC-9_Lapatinib_30min_R1 1 DLQSPDFTTGFHSDK 15 0 E9PDR5;E7EPI0;Q9P2D0-2;Q9P2D0 E9PDR5 IBTK Inhibitor of Bruton tyrosine kinase 1 DLQS(0.004)PDFT(0.498)T(0.498)GFHSDK 168.41 0.00049794 3964500.0 10369.0 15004.0 14747.0 12683.0 16798.0 14913.0 15686.0 14019.0 16794.0 12631.0 True False 10221.136158558282 14969.25915984301 13534.558585066203 13615.750129247717 15809.974666138673 14275.205753900931 16498.14432781254 14670.373918875646 14902.482871339953 14814.251520250444 0.6899529243570914 1.0104634135164154 0.9136174424043662 0.9190980800235214 1.067213867978893 0.9636130272519904 1.1136670864039462 0.990287892629734 1.0059558426538728 1.0 13.85469811652693 -4.34342532205422 1.9307472725156165 1.0012122251942286 3.440443969556903e-17 0.6991577579227821 0.05970779909545422 2.3375546984977618 2.9088440621602247 0.016340587010783326 6.414718863527218 4.534972709849892e-05 4.34342532205422 -1.0012122251942286 DLQSPDFT(ph)TGFHSDKIEAK ddPTM_PC-9_AZD4547_30min_R2 1 DLQSPDFTTGFHSDKIEAK 19 1 E9PDR5;E7EPI0;Q9P2D0-2;Q9P2D0 E9PDR5 IBTK Inhibitor of Bruton tyrosine kinase 1 DLQS(0.075)PDFT(0.865)T(0.055)GFHS(0.005)DKIEAK 92.8 0.00061746 13260000.0 25702.0 23166.0 31736.0 46665.0 41701.0 37473.0 29348.0 39263.0 30639.0 33210.0 True False 33874.70136518925 30653.95646417906 31315.15990406598 35907.105217063 35911.535961656045 35129.80738615657 31959.91514539057 33195.80552398289 32258.51498924178 32047.328008337303 1.0570210832047071 0.9565214440406468 0.9771535366667434 1.12043990711867 1.1205781634061176 1.096185222587585 0.9972723821803804 1.0358369195505723 1.0065898467681778 1.0 14.967916454651837 -5.729168845394253 24.999544746153887 1.0575242201399275 0.9928609214517066 0.20973333162629992 0.05011651150547939 294.5843559639948 228208.5165193404 0.01456858052961866 0.02523075069096138 1.8656542191153517e-06 5.729168845394253 -0.06466329868822096 DLQSPDFT(ph)TGFHSDKIEAK ddPTM_PC-9_Lapatinib_30min_R1 1 DLQSPDFTTGFHSDKIEAK 19 1 E9PDR5;E7EPI0;Q9P2D0-2;Q9P2D0 E9PDR5 IBTK Inhibitor of Bruton tyrosine kinase 1 DLQS(0.093)PDFT(0.841)T(0.066)GFHSDKIEAK 122.65 2.2466999999999997e-05 13759000.0 34386.0 21667.0 23215.0 27640.0 26448.0 23550.0 21471.0 24193.0 27756.0 24196.0 True False 33895.6493343799 21616.831392716525 21306.352312491494 29672.73780433704 24892.380638768638 22542.8213977313 22582.663321590157 25317.095100888695 24629.826996362495 28378.246360856603 1.1944236759158486 0.7617395070096226 0.7507987647143802 1.045615624976249 0.8771641602598751 0.7943697827934015 0.7957737428320957 0.892130358548501 0.8679122269632393 1.0 14.79249782008731 -6.510928139359168 24.346957317709972 0.8561109033842043 0.918315666007015 0.04510330284557529 0.13214091036264317 1540.547083732035 3138563.1746602273 0.042051903583955746 0.04521048996127272 3.0836981528938353e-07 6.510928139359168 0.062204762622810716 DLQSPDFTT(ph)GFHSDKIEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLQSPDFTTGFHSDKIEAK 19 1 E9PDR5;E7EPI0;Q9P2D0-2;Q9P2D0 E9PDR5 IBTK Inhibitor of Bruton tyrosine kinase 1 DLQS(0.004)PDFT(0.36)T(0.537)GFHS(0.099)DKIEAK 89.20100000000001 0.00077188 8405700.0 24362.0 20742.0 23361.0 30821.0 32952.0 30485.0 33453.0 31026.0 26272.0 21899.0 True False 28486.005428567023 22801.128680897556 23918.014837085866 29094.1992930302 26495.292147911234 28886.31293422463 30284.08966125371 30211.60037476432 26656.1782982591 25869.11534761139 1.1011588547111744 0.8814034950369064 0.924577996413562 1.124669278484492 1.0242055745581444 1.1166331954560569 1.1706658404942314 1.1678636848922586 1.0304248112110406 1.0 14.658943098224736 -5.764022829625192 24.999995052485772 1.0992814864350822 0.9602824409435388 0.3418528211530729 0.07636896697561364 65.52358488456868 634080.8290797309 0.021162894705658644 0.033082722059571135 1.721778063633328e-06 5.764022829625192 -0.1389990454915434 DLQSPDFTTGFHS(ph)DKIEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLQSPDFTTGFHSDKIEAK 19 1 E9PDR5;E7EPI0;Q9P2D0-2;Q9P2D0 E9PDR5 IBTK Inhibitor of Bruton tyrosine kinase 1 DLQS(0.013)PDFT(0.259)T(0.129)GFHS(0.6)DKIEAK 53.773 0.017188 7892200.0 9365.4 10363.0 10925.0 16595.0 11752.0 18013.0 14129.0 13449.0 13565.0 13403.0 True False 10950.777244918385 11391.770153318927 11185.49343329322 15665.235951715913 9449.279962437882 17068.3665699258 12790.598834898323 13095.978000393396 13763.362462541278 15832.857801910373 0.6916488091996302 0.7195018294135384 0.7064734347543747 0.9894130388656535 0.5968145536744316 1.0780344763701695 0.807851557496779 0.8271392419638387 0.8692911055438525 1.0 13.950634062347998 -2.117390382373172 0.16007264182483938 0.9858944920273327 1.9938587366671255e-14 0.2849079962862754 0.12509687877208867 71.84443896024403 0.8817426392835377 0.37288018317050187 16.09765177299024 0.0076314948877183875 2.117390382373172 -0.9858944920273127 DLRDDRDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLRDDRDR 8 2 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 84.916 0.02852 8510000.0 9297.1 9191.2 10843.0 12472.0 14340.0 9945.0 12229.0 13697.0 10487.0 10658.0 False True 10870.915403904875 10103.641593475348 11101.538242306491 11773.234274769566 11530.179940551328 9423.466692828068 11070.580589707097 13337.468263171113 10640.352535545184 12590.211031318428 0.8634418737591637 0.802499780848972 0.8817595046414369 0.9351101618140781 0.9158051371712318 0.7484756744257095 0.8793006377866728 1.0593522404027913 0.8451290061045897 1.0 13.620014844598833 -7.5480873066591565 24.44229183053188 0.965209780486022 0.8585094631703037 0.3314731383864601 0.07032242038146005 211.48613162908632 205054.32488737226 0.03279118707776339 0.018933013459115206 2.830822855410749e-08 7.5480873066591565 -0.10670031731571827 DLRPVDNR ddPTM_PC-9_Lapatinib_30min_R1 1 DLRPVDNR 8 1 P42285 P42285 SKIV2L2 Superkiller viralicidic activity 2-like 2 0 76.47800000000001 0.045685 0.0 7609.4 9581.4 8929.4 8676.7 9997.2 6869.4 7802.2 8693.3 8952.3 8352.2 False True 7500.888560606944 9559.21485697946 8195.259200480781 9314.813462622691 9409.184351251433 6575.611775353519 8206.159739542207 9097.222454451934 7943.997702101739 9795.866641393055 0.7657197505028769 0.9758416694431499 0.8366037942831106 0.9508922286939224 0.9605259744443977 0.6712639132476401 0.8377165635214509 0.9286796959863709 0.8109540475504101 1.0 13.257957418189283 -10.960002253572824 2.7593306666674855 1.0038003163272247 0.8640034326925189 0.17162010292418284 0.09198981375510915 29187112.21486913 31890938.375991527 862851.5795354755 0.022916538905736694 1.0964725064852289e-11 10.960002253572824 -0.13979688363470577 DLRS(ph)PLTATPTFVTDSESTR ddPTM_PC-9_AZD4547_30min_R2 1 DLRSPLTATPTFVTDSESTR 20 1 A0A087WUK4;P13056-2;P13056-3;P13056 A0A087WUK4 NR2C1 Nuclear receptor subfamily 2 group C member 1 1 DLRS(0.88)PLT(0.101)AT(0.018)PTFVTDSESTR 52.498000000000005 0.016942 5664200.0 9807.2 6391.4 8438.2 11771.0 12584.0 14799.0 9034.3 16907.0 12235.0 11032.0 True False 12925.685597567668 8457.295059360882 8326.303954578063 9057.37781013712 10836.928815651416 13873.616190530009 9838.335198241866 14294.411634209779 12881.71712175245 10645.773037879468 1.214161296842971 0.7944275187220684 0.7821230008334444 0.8507956893228358 1.0179560260294658 1.303204205196309 0.9241541373496691 1.3427312026423854 1.210031162219701 1.0 13.377993093775746 -6.531143178464198 5.995436458288805 1.1636910685095907 0.896966418557726 0.335775471144952 0.16261635111683623 0.16861351493517976 23.606184241985957 0.05247024080461409 0.05449310131271931 2.9434510751118e-07 6.531143178464198 -0.26672464995186473 DLRS(ph)PLTATPTFVTDSESTR ddPTM_PC-9_Lapatinib_30min_R1 2 DLRSPLTATPTFVTDSESTR 20 1 A0A087WUK4;P13056-2;P13056-3;P13056 A0A087WUK4 NR2C1 Nuclear receptor subfamily 2 group C member 1 1 DLRS(0.915)PLT(0.082)AT(0.003)PTFVTDSESTR;DLRS(0.973)PLT(0.027)ATPTFVTDSESTR 93.115 0.000292 10914200.0 29069.7 27178.4 25564.5 25061.1 26026.8 35690.0 31209.2 28593.0 34095.0 30311.8 True False 28655.16074726993 27115.47008463593 23462.685491823744 26904.17689537885 24495.95479465756 34163.621897453515 32825.059668211616 29921.535163878412 30254.862063733213 35551.15424206532 0.8060261715318424 0.7627170105366647 0.6599697250915669 0.756773653878864 0.6890340220142029 0.9609708215051417 0.9233190980160049 0.8416473614371217 0.8510233411193903 1.0 15.117608780245643 -6.759319153009726 24.999999978983972 0.9059905280538961 0.7335012186606155 0.7082489351086716 0.05775951373244845 33.6932246130118 397284.23493820376 0.02001986719402957 0.019091972184825345 1.740527329858212e-07 6.759319153009726 -0.17248930939328067 DLRT(ph)AY(ph)RSPNT(ph)EEIFNMLTK ddPTM_PC-9_AZD4547_30min_R2 1 DLRTAYRSPNTEEIFNMLTK 20 2 Q7KZ85 Q7KZ85 SUPT6H Transcription elongation factor SPT6 3 DLRT(0.949)AY(0.844)RS(0.342)PNT(0.864)EEIFNMLT(0.001)K 47.018 0.026335 3892800.0 6991.7 7196.4 8566.5 10045.0 10102.0 9716.1 8248.4 7862.4 9875.5 8544.7 True False 9214.915163605698 9522.495566727894 8452.902612748332 7729.28044370295 8699.511673212852 9108.550731049978 8982.491620731895 6647.446739978177 10397.498768767171 8245.552653804269 1.117561860375022 1.154864442268097 1.0251468843447866 0.9373877977890148 1.0550550143172197 1.1046622480601764 1.089374114491601 0.8061857123562518 1.2609826418329952 1.0 13.00940047743732 -5.266289682950912 23.977357426193194 1.0296088565629284 1.1362131579726853 0.11616962254952101 0.11108609063860315 412.9696815857462 2041525.7693329435 0.02759897499046751 0.060682487617107386 5.4163948570582376e-06 5.266289682950912 0.10660430140975685 DLS(ph)ALMHELS(ph)NDGAR ddPTM_PC-9_Lapatinib_30min_R1 1 DLSALMHELSNDGAR 15 0 Q9BSF8;B7Z503;Q9BSF8-2 Q9BSF8 BTBD10 BTB/POZ domain-containing protein 10 2 DLS(1)ALMHELS(1)NDGAR 79.32600000000001 0.038141 4429500.0 4349.5 1640.3 4420.5 2061.5 1840.9 3571.9 2065.1 1404.4 3832.5 879.8 True False 4287.4753323993855 1636.5019861297312 4057.0635536234604 2213.1095869624046 1732.621881348653 3419.138163505582 2172.020773388095 1469.6535510142646 3400.843491985848 1031.8722577401888 4.155044677515608 1.5859540498876168 3.9317498102996513 2.1447515139220217 1.6791050135828958 3.313528528224541 2.10493184315745 1.4242591948666412 3.2957989387501616 1.0 10.011048665760754 -1.5229101340641709 0.0686721996736226 1.0681411453327451e-08 8.092081685902727 0.2525370048563008 0.9178078594034714 403.7996139066028 2.058961524874577 43.268088776404696 317.13634405360784 0.029997831817981744 1.5229101340641709 8.092081675221316 DLS(ph)LEEIQK ddPTM_PC-9_AZD4547_30min_R2 4 DLSLEEIQK 9 0 P16949;A2A2D0;P16949-2;E5RGX5;Q93045;Q93045-2 P16949;E5RGX5 STMN1;STMN2 Stathmin;Stathmin-2 1 DLS(1)LEEIQK;DLS(1)LEEIQK;DLS(1)LEEIQK;DLS(1)LEEIQK 123.67 0.0014834000000000002 25361100.0 87577.0 86727.0 91139.0 125407.0 112079.0 111905.0 92932.0 111611.0 93946.0 96955.0 True False 115424.66428523748 114759.80671107923 89930.43731083526 96496.35366883589 96518.76547436383 104907.56265972454 101202.76796686107 94364.08451563177 98911.79376543972 93560.63496080502 1.2336883384084756 1.226582170580128 0.9611995188842984 1.0313777125311379 1.031617255641735 1.121278865878508 1.081681072485854 1.0085874743706402 1.0571945541720238 1.0 16.5136140323011 -5.244536217328749 24.40433610703006 1.0411911365266833 1.2301353270629412 0.7716574469534225 0.042048984306244166 286.2535953936645 413282.94894954236 0.011251111682266873 0.029582975456229302 5.694607328347597e-06 5.244536217328749 0.18894419053625788 DLS(ph)LEEIQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 DLSLEEIQK 9 0 P16949;A2A2D0;P16949-2;E5RGX5;Q93045;Q93045-2 P16949;E5RGX5 STMN1;STMN2 Stathmin;Stathmin-2 1 DLS(1)LEEIQK;DLS(1)LEEIQK;DLS(1)LEEIQK;DLS(1)LEEIQK;DLS(1)LEEIQK 145.23 0.00050495 22540600.0 72673.2 96350.3 76696.1 87444.0 98657.0 86498.0 93156.0 83539.0 81905.3 74219.1 True False 84975.33739887267 105915.32102705071 78524.82589557907 82544.7961772729 79325.86906520027 81961.89260897353 84331.58928896516 81346.1897668871 83103.01006289574 87674.43531192782 0.9692145389536606 1.208052502992754 0.8956410795941108 0.9414921907805314 0.9047776445091998 0.9348436898095753 0.9618720552796319 0.9278210857871383 0.947859085344914 1.0 16.419868613036606 -5.281336677085134 24.99950107834032 0.9362045373599459 1.0886335456909202 0.49645072313922944 0.06009945872269291 503.32002657812524 632384.3072421326 0.014273013368725062 0.02977038516469039 5.231946843518568e-06 5.281336677085134 0.15242900833097428 DLS(ph)LEEIQK ddPTM_PC-9_Lapatinib_30min_R1 4 DLSLEEIQK 9 0 P16949;A2A2D0;P16949-2;E5RGX5;Q93045;Q93045-2 P16949;E5RGX5 STMN1;STMN2 Stathmin;Stathmin-2 1 DLS(1)LEEIQK;DLS(1)LEEIQK;DLS(1)LEEIQK;DLS(1)LEEIQK 130.56 0.0012618 26871800.0 102777.0 93495.0 116217.0 95349.0 102603.0 111326.0 100322.0 93835.0 109703.0 98339.0 True False 101311.38113300665 93278.51807181565 106662.08687059314 102361.28353493987 96568.09326525927 106564.84649358106 105516.18228068414 98194.91666150917 97347.09291619674 115336.76512151922 0.878396242744147 0.8087492134319623 0.9247882646805083 0.8874991718997118 0.8372706930310972 0.9239451651110898 0.9148529713791775 0.8513756785015659 0.8440248242928566 1.0 16.815492938890998 -11.710030666379748 2.503872980548042 1.3667676909862685 0.8753290537277049 0.5034696469460902 0.03736901470030542 7087757.907155011 1859235.791993958 14751355.62355102 0.009738175059757005 1.949706922291771e-12 11.710030666379748 -0.4914386372585636 DLS(ph)LEVDR ddPTM_PC-9_Lapatinib_30min_R1 1 DLSLEVDR 8 0 E7EMW7;O95071-2;O95071;E5RFK7 E7EMW7 UBR5 E3 ubiquitin-protein ligase UBR5 1 DLS(1)LEVDR 82.831 0.015913999999999998 624280.0 4930.0 4809.1 4284.2 4273.2 4676.7 4842.6 5355.2 5092.8 4084.0 4849.8 True False 4859.697295948725 4797.964824420222 3931.969613490245 4587.465382977318 4401.6257007459635 4635.493286651957 5632.466052805157 5329.430080180462 3624.0169135734404 5688.081468047707 0.8543649248428742 0.8435119734786436 0.6912646444284836 0.8065048661393122 0.7738330974110876 0.8149484694780532 0.9902224650692919 0.9369468616295429 0.6371246498368622 1.0 12.473726412894155 -7.021045463725293 23.886241270764547 0.8882142811376659 0.7919250623145259 0.1683964528479167 0.10273993348226387 822.8230918234954 933887.647159022 0.03867226791679676 0.030327795017290028 9.526964266389739e-08 7.021045463725293 -0.09628921882314001 DLS(ph)LEVDRDR ddPTM_PC-9_AZD4547_30min_R2 2 DLSLEVDRDR 10 1 E7EMW7;O95071-2;O95071;E5RFK7 E7EMW7 UBR5 E3 ubiquitin-protein ligase UBR5 1 DLS(1)LEVDRDR;DLS(1)LEVDRDR 170.89 7.5978e-05 2305900.0 43015.0 45615.0 52634.0 48574.0 46708.0 56326.0 54507.0 61019.0 51740.0 50154.0 True False 56692.875232418366 60359.15670005734 51936.03876955535 37376.01476081901 40223.400438767196 52803.92631581819 59358.0174059495 51589.915627127615 54474.87077069652 48398.12372568951 1.1713858073040555 1.2471383610273918 1.0731002520659274 0.7722616474278731 0.8310942107331486 1.0910325081009309 1.2264528629741596 1.0659486702321048 1.1255574922583518 1.0 15.562663498451961 -5.401569896531024 5.230499924860326 1.0163229792060464 1.2059548554763395 0.2624990042838471 0.12720121814062546 0.33440811758982214 12.782247781697382 0.03851784800281987 0.08227079682654853 3.966706825392076e-06 5.401569896531024 0.1896318762702931 DLS(ph)LEVDRDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DLSLEVDRDR 10 1 E7EMW7;O95071-2;O95071;E5RFK7 E7EMW7 UBR5 E3 ubiquitin-protein ligase UBR5 1 DLS(1)LEVDRDR;DLS(1)LEVDRDR 152.7 1.3045e-08 2323800.0 38940.0 53914.0 48099.0 46071.0 46152.0 36531.0 44534.0 38694.0 40280.0 34068.0 True False 45531.772899942516 59266.22561478695 49245.862576473286 43489.791234197284 37108.84690490411 34615.250050849914 40315.41712176105 37678.32349968189 40869.01879772673 40244.258717860364 1.1313855528847288 1.4726628717473345 1.2236742369071893 1.080645851600605 0.9220904568043451 0.8601289017031316 1.0017681628676416 0.9362409620669763 1.0155242039428867 1.0 15.296495361284345 -5.842040200970241 2.4502582560160797 0.9519937142672895 1.3087462361706432 0.7197030986767284 0.08948166022778885 0.1344957546691092 1.643098043595911 0.02578887869869737 0.044379766638841245 1.4386654003679002e-06 5.842040200970241 0.3567525219033537 DLS(ph)LEVDRDR ddPTM_PC-9_Lapatinib_30min_R1 2 DLSLEVDRDR 10 1 E7EMW7;O95071-2;O95071;E5RFK7 E7EMW7 UBR5 E3 ubiquitin-protein ligase UBR5 1 DLS(1)LEVDRDR;DLS(1)LEVDRDR 145.28 0.00060724 6344300.0 41749.0 63249.0 64292.0 54767.0 66767.0 56607.0 63488.0 58172.0 52787.0 49636.0 True False 41153.65160417107 63102.550826506995 59006.15993429689 58794.74787735627 62839.89632897257 54186.05056736205 66775.09799083011 60874.88348732677 46841.572188247126 58215.51646418738 0.7069189471073007 1.0839472817410456 1.0135813184891334 1.009949777110115 1.0794355207280517 0.9307836442659725 1.1470326477633905 1.0456814125281422 0.8046234927257375 1.0 15.829116112449482 -4.753940780470009 24.99990490992727 1.01786155362315 0.7069183972689884 0.5150081776886697 0.08892176709103265 213.61056373753095 712106.5847537209 0.02139703408773537 0.21957995664478233 1.7622163223350514e-05 4.753940780470009 -0.3109431563541615 DLS(ph)PEPAPDEGPR ddPTM_PC-9_AZD4547_30min_R2 1 DLSPEPAPDEGPR 13 0 Q8TBE0-3;Q8TBE0-2;Q8TBE0 Q8TBE0-3 BAHD1 Bromo adjacent homology domain-containing 1 protein 1 DLS(1)PEPAPDEGPR 122.78 0.00017656 8621600.0 19449.0 17147.0 25477.0 24191.0 20092.0 24809.0 19847.0 27753.0 26870.0 20021.0 True False 25633.377435669063 22689.432422139278 25139.158333623905 18614.138697224287 17302.572613164975 23257.689308119407 21613.344551266437 23464.41155049531 28290.293343807803 19320.070883918113 1.3267745025203868 1.174396955294082 1.301193897510467 0.9634612009999695 0.8955750067960419 1.20380972967749 1.118699029684059 1.2145095994459791 1.4642955253003982 1.0 14.237812766874768 -10.819479675673078 14.862359979926966 1.0000080584024882 1.1723468165027855 0.1044284782176148 0.15860935262757467 2.2257788756681556e-10 0.0 0.16161002096571056 0.03919618803111749 1.5153757193380925e-11 10.819479675673078 0.1723387581002973 DLS(ph)PEPAPDEGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLSPEPAPDEGPR 13 0 Q8TBE0-3;Q8TBE0-2;Q8TBE0 Q8TBE0-3 BAHD1 Bromo adjacent homology domain-containing 1 protein 1 DLS(1)PEPAPDEGPR 99.161 0.0025765999999999996 5765900.0 16359.0 18402.0 21576.0 18368.0 22110.0 18224.0 16601.0 20577.0 16614.0 16410.0 True False 19128.25559502207 20228.82894541879 22090.453667435664 17338.900509859464 17777.704217963026 17268.301358481516 15028.433099168167 20036.875553133683 16856.948319399984 19385.003098511475 0.9867553540133754 1.043529827806533 1.1395641029911383 0.8944491998142046 0.9170854462916299 0.8908072529432561 0.7752608045918838 1.0336276683222332 0.869587084084314 1.0 14.242653345239873 -5.77982917302623 24.994577559134623 0.9066346986796652 1.0553077702821212 0.44046823033293825 0.07478063675062999 204.91149510160497 278505.8261403722 0.020738123106833536 0.030824201228277295 1.6602398237999103e-06 5.77982917302623 0.14867307160245602 DLS(ph)PEPAPDEGPRR ddPTM_PC-9_AZD4547_30min_R2 1 DLSPEPAPDEGPRR 14 1 Q8TBE0-3;Q8TBE0-2;Q8TBE0 Q8TBE0-3 BAHD1 Bromo adjacent homology domain-containing 1 protein 1 DLS(1)PEPAPDEGPRR 96.48899999999999 0.0013464 16199000.0 92765.0 79850.0 86572.0 95543.0 87196.0 91780.0 85770.0 85775.0 77976.0 93669.0 True False 122262.34036813428 105659.95094814386 85423.99871486 73517.03747463522 75090.34051251906 86040.98209114413 93403.3638414935 72520.44466341428 82097.65216884098 90389.67682062453 1.3526139783723317 1.1689382534005814 0.9450636590324495 0.8133344432741746 0.83074022558498 0.9518894758512054 1.0333410531697058 0.802308927460033 0.908263587796217 1.0 16.46387039499836 -5.077707767798754 2.213584488961661 0.8997876437043717 1.360361967212157 0.7991274273545935 0.07317509867360596 0.1626274814911123 1.3565930706416274 0.0208499876621189 0.11485217415377068 8.36165475951704e-06 5.077707767798754 0.46057432350778527 DLS(ph)PEPAPDEGPRR ddPTM_PC-9_Lapatinib_30min_R1 1 DLSPEPAPDEGPRR 14 1 Q8TBE0-3;Q8TBE0-2;Q8TBE0 Q8TBE0-3 BAHD1 Bromo adjacent homology domain-containing 1 protein 1 DLS(1)PEPAPDEGPRR 106.3 0.00040757 13413000.0 50372.0 72007.0 48035.0 72846.0 57681.0 63988.0 53044.0 60081.0 59713.0 51721.0 True False 49653.686042906535 71840.272215597 44085.747720462125 78203.33784713242 54288.31698520925 61251.38240331337 55790.35877371465 62872.58259647395 52987.49313423382 60660.90593609954 0.8185450790202827 1.1842927682496838 0.7267571599887124 1.2891884260599762 0.894947349490573 1.0097340528978556 0.9197086313297803 1.0364596707919957 0.8735031618230541 1.0 15.888479423501618 DLS(ph)PQHMVVR ddPTM_PC-9_Lapatinib_30min_R1 1 DLSPQHMVVR 10 0 A0A2R8Y5E8;A0A2R8Y3N3;A0A2R8Y5P7;P49590-2;P49590;D6RB22 A0A2R8Y5E8 HARS2 Probable histidine--tRNA ligase, mitochondrial 1 DLS(1)PQHMVVR 82.774 0.008191 2564900.0 22881.0 21641.0 18923.0 14374.0 15226.0 14171.0 12317.0 11933.0 19871.0 11825.0 True False 22554.712744138502 21590.89159411909 17367.22398489237 15431.111910258347 14330.436615467765 13564.939364214444 12954.713992456149 12487.45074355826 17632.918729093497 13868.935494177926 1.626275697482824 1.5567807351316028 1.2522391492975795 1.1126385234639105 1.0332758863492857 0.9780807885297976 0.9340813502156989 0.9003899937958755 1.2713966934589653 1.0 13.759569437852113 -5.401277582467568 1.347426950601974 1.0072137064647781 1.6765374480505393 0.847847630782786 0.09480910458148745 0.19637054392696743 0.6059470750966556 0.029865561165554014 0.13146014728978767 3.9693776272366355e-06 5.401277582467568 0.6693237415857611 DLS(ph)PTLIDNSAAK ddPTM_PC-9_AZD4547_30min_R2 4 DLSPTLIDNSAAK 13 0 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 DLS(0.991)PT(0.009)LIDNSAAK;DLS(0.891)PT(0.109)LIDNSAAK;DLS(0.999)PT(0.001)LIDNSAAK;DLS(0.988)PT(0.012)LIDNSAAK 184.0 4.6298e-05 40841200.0 98486.0 102702.0 112644.0 114481.0 114126.0 109914.0 98142.0 111796.0 96236.0 88611.0 True False 129802.49936394165 135898.41305292753 111150.26695971788 88089.17416381846 98281.57485815558 103041.06020446762 106876.44787375379 94520.497016509 101322.83849031213 85508.75586108927 1.518002432111262 1.5892923675991413 1.2998700055966639 1.030177240643299 1.149374398778717 1.2050351939614223 1.249888935904725 1.1053896886309456 1.1849410913534184 1.0 16.383784535110642 -5.436827831003603 3.6491811641307272 1.1453822073599345 1.5507514759260497 0.8302921920207378 0.07536910351099481 0.08856790665231291 2.1894805941442588 0.020327652275545026 0.04520810347842347 3.657397544648608e-06 5.436827831003603 0.4053692685661152 DLS(ph)PTLIDNSAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DLSPTLIDNSAAK 13 0 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 DLS(0.995)PT(0.005)LIDNSAAK;DLS(0.992)PT(0.008)LIDNSAAK 198.85 6.2608e-07 13517800.0 51062.0 69519.0 48609.0 58849.0 62198.0 47267.0 67677.0 51488.0 46150.0 46337.0 True False 59705.78807952918 76420.38688493487 49768.02291065907 55551.88132103222 50010.74839207888 44788.235311202065 61266.14462095083 50136.49455604541 46824.85644277776 54737.53129650981 1.090765086867119 1.3961241048846424 0.9092120475998228 1.014877361204164 0.9136463996005548 0.8182363042386214 1.1192712416838078 0.9159436563636588 0.8554433372073434 1.0 15.740242749097101 -5.275968688980984 24.93130590673584 0.9436380603212247 1.2434445985855012 0.5625208915262918 0.10586611910466572 453.2024052486095 777664.3288952953 0.02653221056148268 0.055603674918674455 5.297016320351929e-06 5.275968688980984 0.2998065382642765 DLS(ph)PTLIDNSAAK ddPTM_PC-9_Lapatinib_30min_R1 3 DLSPTLIDNSAAK 13 0 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 DLS(0.991)PT(0.009)LIDNSAAK;DLS(0.953)PT(0.047)LIDNSAAK;DLS(0.948)PT(0.052)LIDNSAAK 154.13 6.186e-05 27257500.0 62278.0 64319.0 68297.0 57552.0 79399.0 78491.0 76991.0 70128.0 77847.0 67184.0 True False 61389.90429961357 64170.073307247556 62681.884294043964 61784.5660678439 74728.90692444006 75134.1229014576 80977.21726014375 73386.40289485073 69079.05109474823 78796.66488294714 0.779092673412112 0.8143754993002882 0.7954890525780277 0.7841012834696138 0.948376521207468 0.953519073593657 1.0276731557158647 0.9313389469448564 0.8766748084752765 1.0 16.26584694757301 -6.273342552148533 8.844538404115399 0.9563799140383524 0.7948711819232589 0.8117844500740339 0.03844743493724714 0.08877279027143567 56.37295795068313 0.012260896879801196 0.014412205705660461 5.329143905306384e-07 6.273342552148533 -0.16150873211509353 DLS(ph)QMTS(ph)ITQNDIIS(ph)T(ph)LQSLNMVK ddPTM_PC-9_AZD4547_30min_R2 1 DLSQMTSITQNDIISTLQSLNMVK 24 0 Q9H7Z6;Q9H7Z6-2 Q9H7Z6 KAT8 Histone acetyltransferase KAT8 4 DLS(0.544)QMT(0.465)S(0.504)IT(0.504)QNDIIS(0.959)T(0.512)LQS(0.512)LNMVK 41.521 0.026499 1616700.0 2567.2 3177.0 5401.2 3964.6 4819.4 3726.1 4395.2 5174.1 4994.2 4062.7 True False 3383.516198922802 4203.903120378872 5329.576558918614 3050.6227224594018 4150.309498899428 3493.1063779670167 4786.364285369386 4374.561733989761 5258.1832161386255 3920.466109589638 0.8630392673581765 1.072296763411864 1.3594242138408563 0.7781275586077482 1.0586265466617815 0.8909926218779751 1.2208661295813072 1.1158269480481886 1.3412137917164673 1.0 11.936809473190685 -7.280839150483759 24.81848146291835 1.179128974295866 1.015272538345191 0.1864372451459867 0.1680885920655111 1366.1104738078648 1747682.2832307813 0.06977029405725316 0.047119813866190484 5.2379439823802645e-08 7.280839150483759 -0.1638564359506749 DLS(ph)SEGQTK ddPTM_PC-9_Lapatinib_30min_R1 1 DLSSEGQTK 9 0 Q7L2Z9 Q7L2Z9 CENPQ Centromere protein Q 1 DLS(0.98)S(0.02)EGQTK 119.03 0.0017621 3406600.0 18590.0 16258.0 14275.0 15078.0 19447.0 16886.0 12997.0 15051.0 16056.0 13902.0 True False 18324.90319101152 16220.355599888551 13101.36460309351 16186.886418733498 18303.16569427306 16163.825143188576 13669.921065190594 15750.324406376873 14247.604202824472 16304.942176749384 1.1238864261133394 0.994812212398922 0.8035210711618389 0.9927595107829188 1.1225532415792994 0.9913451374416992 0.8383912630296664 0.9659846833947446 0.8738212039256019 1.0 13.99302170432397 -7.038140703878574 23.46958423299451 0.9164508288420878 1.0008794193524928 0.16779777137958807 0.09291552708078166 549.6802026315589 338239.1872697817 0.03735112638331729 0.028942789761524854 9.159236986568123e-08 7.038140703878574 0.08442859051040497 DLS(ph)TPGLEK ddPTM_PC-9_AZD4547_30min_R2 3 DLSTPGLEK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DLS(0.986)T(0.014)PGLEK;DLS(0.971)T(0.029)PGLEK;DLS(0.982)T(0.018)PGLEK 132.32 0.0012054000000000001 121811000.0 746900.0 822530.0 955920.0 1178190.0 939160.0 995560.0 1212960.0 1385350.0 1281130.0 1075230.0 True False 984398.6635148963 1088396.7370491773 943243.8762129667 906576.4983540437 808773.845081627 933307.4758189098 1320911.0901851223 1171275.9896760245 1348847.9163212678 1037586.5249745423 0.9487388664179587 1.0489696144385467 0.9090749094260931 0.8737358056729649 0.7794760490952508 0.8994984546872454 1.2730611456403904 1.1288465698846295 1.2999859615123301 1.0 19.98480021802157 -7.251389679786197 24.864231227271542 1.1862106332471805 0.908624417143388 0.6332748507745456 0.09886295043902105 406.76989114017016 1006401.6530474633 0.03868345128414384 0.029607259700217797 5.605447898096629e-08 7.251389679786197 -0.2775862161037924 DLS(ph)TPGLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DLSTPGLEK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DLS(0.724)T(0.276)PGLEK;DLS(0.99)T(0.01)PGLEK;DLS(0.5)T(0.5)PGLEK;DLS(0.922)T(0.078)PGLEK;DLS(0.623)T(0.377)PGLEK;DLS(0.904)T(0.096)PGLEK 130.01 0.0012797000000000002 116119100.0 1102334.0 1165998.0 852604.0 1110794.0 1260528.0 1165133.0 1331874.0 1669623.0 1201053.0 926515.0 True False 1288937.3741110766 1281750.5756276709 872933.3128786775 1048559.8134227385 1013536.5871759587 1104031.3743805776 1205709.2527872715 1625797.1653617949 1218616.1279559613 1094484.8352112952 1.1776658137636429 1.1710994381938815 0.7975746075185718 0.9580395997175323 0.9260398632935749 1.0087224042418454 1.1016226209790325 1.485445127294 1.1134152696786357 1.0 20.061820534517288 -7.528618452509281 24.999549133376917 1.2383649181964198 1.0033551379146375 0.22619424996923476 0.15569419531260498 190.59080399260756 830109.4822284379 0.07328874307068156 0.04246678651650474 2.9606123571774318e-08 7.528618452509281 -0.23500978028178232 DLS(ph)TPGLEK ddPTM_PC-9_Lapatinib_30min_R1 5 DLSTPGLEK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DLS(0.984)T(0.016)PGLEK;DLS(0.5)T(0.5)PGLEK;DLS(0.986)T(0.014)PGLEK;DLS(0.5)T(0.5)PGLEK;DLS(0.627)T(0.373)PGLEK 138.25 0.00089903 218177000.0 1398010.0 1585050.0 1291160.0 1192900.0 1737270.0 1472050.0 1746520.0 1625790.0 1401290.0 1732820.0 True False 1378074.1210363652 1581379.914110179 1185005.8088217312 1280629.8453977443 1635087.1942042334 1409093.853016151 1836946.2598120102 1701330.1386381965 1243461.9639621282 2032335.6281624883 0.6780740847821155 0.7781096252984379 0.5830758425925643 0.6301271441841574 0.8045360084951015 0.6933371798880317 0.9038596944112341 0.837130499048739 0.6118388846464249 1.0 20.954707243629763 -6.683093046109513 1.5914465050570177 0.8171008011174453 0.6741938968173931 0.2739759604720513 0.11017576662306551 0.5598447323655835 2.937580882783638 0.04604969916917919 0.04456834862829343 2.074469021937717e-07 6.683093046109513 -0.14290690430005226 DLS(ph)TSPKPSPIPSPVLGR ddPTM_PC-9_AZD4547_30min_R2 1 DLSTSPKPSPIPSPVLGR 18 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 DLS(0.348)T(0.302)S(0.348)PKPS(0.003)PIPSPVLGR 51.265 0.029825 25669000.0 112570.0 80522.0 65969.0 66721.0 63509.0 80121.0 44963.0 60700.0 48802.0 70723.0 True False 148364.9183985432 106549.16180646756 65094.20795662112 51339.50427917418 54691.87159513713 75111.0212042336 48964.61989512732 51320.20974723688 51381.57408874238 68247.0092964058 2.1739402199175455 1.5612282927111198 0.9538030842334548 0.7522601328389339 0.8013812203492037 1.100576010269058 0.7174617671884711 0.7519774166857102 0.7528765673171904 1.0 16.058478205541192 -4.9835867342538185 1.7895180875394558 0.8291546627114093 2.3457235611921687 0.9296877072440667 0.11789008329434258 0.13829649764943683 0.6152928727061402 0.034076865053568994 0.31347726798483433 1.0385161765294339e-05 4.9835867342538185 1.5165688984807595 up DLSELGSVR ddPTM_PC-9_Lapatinib_30min_R1 1 DLSELGSVR 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 90.709 0.038537 3843400.0 27244.0 27107.0 29500.0 31910.0 35055.0 31261.0 32420.0 32301.0 32767.0 24749.0 False True 26855.495564062294 27044.235406949116 27074.623873293065 34256.767848639465 32993.13382078172 29924.03990295024 34098.548967721705 33801.822380597936 29076.435408193185 29026.831674030404 0.925195552365064 0.9316978067277295 0.9327447162452824 1.1801759225168262 1.1366426136787042 1.030909616281771 1.1747251422630753 1.1645026491416768 1.0017088924729998 1.0 14.825099487593345 -5.745469015489873 24.821491603470474 1.1071989308661245 0.9300610908064999 0.5815573433973675 0.06519927865223298 146.0572798732184 227003.37054833813 0.017306355855938135 0.029847024787364 1.7969292765692851e-06 5.745469015489873 -0.17713784005962463 DLSHIGDAVVISCAK ddPTM_PC-9_AZD4547_30min_R2 2 DLSHIGDAVVISCAK 15 0 P12004 P12004 PCNA Proliferating cell nuclear antigen 0 ; 169.4 0.00012926 16433400.0 133180.0 136366.0 179016.0 241640.0 216350.0 181714.0 155528.0 200911.0 164387.0 175565.0 False True 175528.469683912 180443.64271752757 176642.1308730237 185933.63130078441 186313.536972837 170351.3948541101 169369.69070234132 169864.8214254874 173076.1612172879 169418.5227878272 1.0360642201073647 1.0650762369325328 1.0426376524026422 1.0974811268637965 1.0997235361694684 1.0055063168473686 0.9997117665490034 1.0026342965947066 1.02158936560934 1.0 17.370232089799188 -6.780562452640484 24.999640700694542 1.0056669304108266 1.0682301815468416 0.714541398351004 0.019690986139081913 142.30668950704612 186036.70734196127 0.007412622692699757 0.006546911610353569 1.657438975811028e-07 6.780562452640484 0.06256325113601502 DLSHIGDAVVISCAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DLSHIGDAVVISCAK 15 0 P12004 P12004 PCNA Proliferating cell nuclear antigen 0 ; 141.85 1.517e-05 10422300.0 136692.0 151937.0 167971.0 185459.0 198577.0 176636.0 180388.0 147677.0 170401.0 143482.0 False True 159831.2558099367 167020.30124334866 171976.0656735648 175068.33349619078 159667.26234692213 167372.89721009342 163300.3427439761 143800.6352267151 172892.79225797986 169494.15079711317 0.942989802646682 0.9854045137125367 1.0146430709542449 1.0328871685120862 0.942022256201903 0.9874847976933498 0.9634570985251807 0.8484106062093343 1.0200516740246388 1.0 17.37087596159428 -6.832958327530696 1.6080478962348306 0.9483898934732938 0.9915298415013342 0.04361530267402436 0.049957388074105935 0.8422142901483699 4.504027985097747 0.02230644113381542 0.01915312262442246 1.4690672343557876e-07 6.832958327530696 0.04313994802804033 DLSHIGDAVVISCAK ddPTM_PC-9_Lapatinib_30min_R1 2 DLSHIGDAVVISCAK 15 0 P12004 P12004 PCNA Proliferating cell nuclear antigen 0 ; 140.31 5.8496000000000004e-05 23926000.0 278720.0 294000.0 298090.0 294490.0 296180.0 277230.0 281090.0 248860.0 292610.0 278280.0 False True 274745.4016890115 293319.2610633056 273582.1908606756 316147.7769898413 278759.27471228404 265373.5191546942 295643.464816067 260422.94410809627 259653.1804800988 326380.3272152079 0.8417952271610123 0.8987038635753846 0.8382312536879148 0.9686483854199353 0.8540933734908489 0.8130806210624112 0.9058250150632587 0.7979125038880766 0.7955540172888217 1.0 18.316194574992515 -6.484344861893185 24.99674353976164 0.8504459354215593 0.8876133120967715 0.020694655108712823 0.06620413850885874 1613.4096787405829 1046611.0764808179 0.01963490835847371 0.02225864433106152 3.2783486463251757e-07 6.484344861893185 0.037167376675212194 DLSLDDFK ddPTM_PC-9_Lapatinib_30min_R1 1 DLSLDDFK 8 0 P30048-2;P30048 P30048-2 PRDX3 Thioredoxin-dependent peroxide reductase, mitochondrial 0 91.069 0.041476 1303000.0 10960.0 11892.0 11394.0 9563.9 9862.0 7874.0 11176.0 8849.6 11315.0 10106.0 False True 10803.708390182157 11864.464804642299 10457.22930211191 10267.26111023513 9281.936549438002 7537.247375190497 11754.638595412025 9260.784723053137 10040.585547767741 11852.808634601444 0.9114893122161198 1.0009834099579427 0.8822574990019265 0.8662302266706907 0.7831001778212806 0.635903911684468 0.9917175715717846 0.7813156365334785 0.8471060199568775 1.0 13.532941339355945 -5.5991017126270775 2.427937458486795 0.8279818890066422 0.955423029503811 0.1479487420794522 0.10174654177299546 0.4663184382991146 5.515828929060064 0.02885243650869095 0.061963217359675186 2.517087351882813e-06 5.5991017126270775 0.12744114049716881 DLSLEEIQK ddPTM_PC-9_AZD4547_30min_R2 1 DLSLEEIQK 9 0 P16949;A2A2D0;P16949-2;E5RGX5;Q93045;Q93045-2 P16949;E5RGX5 STMN1;STMN2 Stathmin;Stathmin-2 0 111.46 0.010292 2987900.0 12620.0 12133.0 12161.0 18380.0 12317.0 14242.0 13035.0 14691.0 13428.0 11735.0 False True 16632.897487693113 16054.754976253344 11999.737194143752 14142.774968169255 10606.997156895939 13351.44548858223 14195.089747859009 12420.843515595667 14137.776666194668 11324.16122185601 1.4687973053219223 1.4177434126659314 1.0596579260090238 1.2489026508094239 0.9366695642255676 1.1790229074815268 1.2535223995629814 1.0968444613472144 1.2484612669509056 1.0 13.467116573672298 -5.20449553377318 6.247971929054355 1.1352759726245785 1.4494538039129192 0.5960626848299473 0.10376817224748192 0.14953005122236396 12.613357798113269 0.025485303009039287 0.06869692439906658 6.244597721089105e-06 5.20449553377318 0.31417783128834076 DLSLEEIQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLSLEEIQK 9 0 P16949;A2A2D0;P16949-2;E5RGX5;Q93045;Q93045-2 P16949;E5RGX5 STMN1;STMN2 Stathmin;Stathmin-2 0 122.13 0.00033192 0.0 13032.0 13152.0 15710.0 13853.0 13831.0 13919.0 15061.0 13001.0 14958.0 11701.0 False True 15238.06020626736 14457.643641460063 16084.585980506783 13076.861322031977 11120.914836664257 13189.063137000905 13634.313047802654 12659.73752569815 15176.732452244198 13822.298674934964 1.102425910814654 1.0459652176144347 1.1636693981786255 0.9460699431813938 0.8045633434929796 0.9541873929346967 0.9863998288885771 0.9158923434822765 1.0979890399681012 1.0 13.754709938196138 -5.777114321671433 24.738463541189216 0.949014487018722 1.0982146691064563 0.4445973403516389 0.07431104649908118 183.78283905639938 290048.7676446565 0.02128873537361303 0.03170384294901211 1.6706507820360194e-06 5.777114321671433 0.14920018208773422 DLSLEEIQK ddPTM_PC-9_Lapatinib_30min_R1 2 DLSLEEIQK 9 0 P16949;A2A2D0;P16949-2;E5RGX5;Q93045;Q93045-2 P16949;E5RGX5 STMN1;STMN2 Stathmin;Stathmin-2 0 ; 138.98 0.0039518 9223100.0 60675.0 54907.0 59548.0 56079.0 56242.0 55990.0 54111.0 52096.0 56120.0 52065.0 False True 59809.763373567745 54779.866214976 54652.19330192731 60203.236734059996 52933.95613602635 53595.4382190648 56912.602812843594 54516.57034579828 49799.17463020117 61064.365877748336 0.9794544250784112 0.8970840100861116 0.8949932176703795 0.985898008907317 0.866855086025143 0.8776876243399232 0.9320100519308326 0.8927722340544921 0.8155193935838091 1.0 15.898043120175158 -6.289177614459214 24.995756478540994 0.8928501564617072 0.9331690391163784 0.12467482489682191 0.052519037074788846 1597.1302006236565 1439217.9087723028 0.015807122208112877 0.0179269704029168 5.138334648966122e-07 6.289177614459214 0.040318882654671206 DLSPPDNHLS(ph)PQNDDALETR ddPTM_PC-9_AZD4547_30min_R2 1 DLSPPDNHLSPQNDDALETR 20 0 O94972-2;O94972-3;O94972 O94972-2 TRIM37 E3 ubiquitin-protein ligase TRIM37 1 DLS(0.003)PPDNHLS(0.996)PQNDDALETR 69.435 0.021164 0.0 3099.8 3117.9 4707.7 7363.0 5181.2 4886.1 3049.0 3787.5 3660.9 4217.7 True False 4085.4719201546077 4125.700201142359 4645.272822043465 5665.574107216009 4461.879814022019 4580.571394590763 3320.3550933043434 3202.2289030915917 3854.407700124525 4070.0396067679644 1.0037916862924334 1.013675688630115 1.1413335669557023 1.3920194038885694 1.0962742983145601 1.125436565033384 0.8158041233267141 0.7867807718054358 0.9470197031289644 1.0 11.990827118517172 -7.25244061419114 23.38997868225449 0.8696328798211167 1.134586242818218 0.5110751576616771 0.11503989714063559 220.05103684714425 571967.277913555 0.047623701283332855 0.03626682597928912 5.5918998647275273e-08 7.25244061419114 0.26495336299710137 DLSPT(ph)LIDNSAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLSPTLIDNSAAK 13 0 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 DLS(0.24)PT(0.756)LIDNS(0.003)AAK 88.22399999999999 0.016403 4564100.0 25850.0 33566.0 24849.0 29452.0 29402.0 29757.0 31890.0 21580.0 25072.0 26044.0 True False 30225.894439227384 36898.2106500341 25441.494400357296 27801.89992467232 23640.889164023014 28196.490535795376 28869.148336393762 21013.547865900025 25438.63056843605 30765.57103580943 0.9824584241926181 1.1993344965736739 0.8269469261839736 0.9036692311776837 0.7684202947673658 0.9164949515475014 0.9383589305978317 0.6830215451369784 0.8268538405748063 1.0 14.909029150014094 -5.274343962598749 24.92980506832754 0.850045066648354 1.0908964604808704 0.4715322389403319 0.09834907525904725 516.0870856865856 997006.6612141493 0.024972476037467092 0.05252103585508307 5.316869946914787e-06 5.274343962598749 0.2408513938325164 DLSS(ph)SPPGPYGQEMYAFR ddPTM_PC-9_AZD4547_30min_R2 1 DLSSSPPGPYGQEMYAFR 18 0 O43741-2;O43741 O43741-2 PRKAB2 5-AMP-activated protein kinase subunit beta-2 1 DLS(0.068)S(0.466)S(0.466)PPGPYGQEMYAFR 125.41 3.9046e-05 25609000.0 23966.0 18382.0 23783.0 31292.0 28195.0 40805.0 26697.0 26946.0 25430.0 27413.0 True False 31586.689476232434 24323.622020398005 23467.621880463863 24078.11285658066 24280.610931126146 38253.45689942408 29072.98128105809 22782.114857480137 26774.177883626053 26453.279213867827 1.1940557244666088 0.9194936409867336 0.8871346985277059 0.9102127816334388 0.9178677144267738 1.4460761779344977 1.099031278731482 0.8612208215583675 1.0121307709023084 1.0 14.69115895301713 -4.742225191138585 23.755189391382427 1.008782736168309 1.1940568878095874 0.1081976937529423 0.1618596946969339 1842.3214984975136 2277501.6405048915 0.04363264453097179 1.437844782961333 1.810401116829754e-05 4.742225191138585 0.18527415164127836 DLSS(ph)SPPGPYGQEMYAFR ddPTM_PC-9_Lapatinib_30min_R1 1 DLSSSPPGPYGQEMYAFR 18 0 O43741-2;O43741 O43741-2 PRKAB2 5-AMP-activated protein kinase subunit beta-2 1 DLS(0.007)S(0.912)S(0.081)PPGPYGQEMYAFR 222.42 1.0367e-28 4416800.0 16586.0 17466.0 16699.0 15192.0 14909.0 15547.0 13507.0 11719.0 15506.0 11611.0 True False 16349.480598500115 17425.55855010783 15326.07268000411 16309.270359026359 14032.081932221783 14882.091051827116 14206.32636974143 12263.50752231285 13759.550994581232 13617.945879314997 1.2005834612204023 1.2796025703536107 1.1254320450255038 1.1976307222515368 1.0304110514593716 1.0928293579454076 1.0432062585386064 0.9005401865299323 1.0103984195943476 1.0 13.733221484278422 -6.346214280298165 0.6613561454667592 0.9685839565695511 1.2501427735413913 0.7564176405346132 0.05339828451757222 0.3847588026291147 0.36500551701957934 0.03498803526993949 0.0591421135195611 4.5059432706632267e-07 6.346214280298165 0.28155881697184015 DLSSS(ph)PPGPYGQEMYAFR ddPTM_PC-9_AZD4547_30min_R2 1 DLSSSPPGPYGQEMYAFR 18 0 O43741-2;O43741 O43741-2 PRKAB2 5-AMP-activated protein kinase subunit beta-2 1 DLS(0.003)S(0.067)S(0.915)PPGPY(0.013)GQEMY(0.001)AFR 102.97 0.00037963 26898000.0 20218.0 19835.0 28809.0 31811.0 30863.0 28565.0 18431.0 28473.0 19667.0 25487.0 True False 26646.903439475387 26246.275855434338 28426.973836533794 24477.46542505071 26578.205184158418 26778.826034359736 20071.323294421913 24073.152094449342 20706.557469023734 24594.70788763904 1.0834405336795137 1.0671513552972651 1.1558166889561148 0.995233020732592 1.0806473207805918 1.0888043946973813 0.816083012090153 0.9787939830156785 0.8419110958187295 1.0 14.586060299763885 -7.24351780637141 24.82389352701397 0.9074298553192867 1.0778240270266124 0.6353716502182207 0.06283084527433976 448.3687232524554 621054.4810029056 0.02249340957865492 0.01738405770324912 5.707976725963054e-08 7.24351780637141 0.17039417170732574 DLSSS(ph)PPGPYGQEMYAFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DLSSSPPGPYGQEMYAFR 18 0 O43741-2;O43741 O43741-2 PRKAB2 5-AMP-activated protein kinase subunit beta-2 1 DLS(0.018)S(0.119)S(0.863)PPGPYGQEMYAFR;DLS(0.007)S(0.04)S(0.94)PPGPY(0.013)GQEMYAFR;DLS(0.111)S(0.237)S(0.631)PPGPY(0.021)GQEMY(0.001)AFR 103.14 0.00037057 41049200.0 74272.0 68731.0 75398.0 93398.0 93969.0 83580.0 90783.0 78260.0 78384.0 73657.0 True False 86844.7826611334 75554.15945264527 77195.7742685074 88165.21286040136 75556.44901211055 79196.91766581901 82183.37702799725 76205.75792332432 79530.21771204109 87010.43103150898 0.9980962239996766 0.8683345037709896 0.8872013775055613 1.0132717631116457 0.8683608173915307 0.9102002682544984 0.9445232721377542 0.8758232434882206 0.9140308439943357 1.0 16.408900744825175 -11.164827266305107 6.9340400962239865 1.000270278217929 0.9178600643124365 0.19293550356491118 0.0489239221842932 0.00019652193297906167 1.0147714317799414e-05 0.0455404479744991 0.01100915844188626 6.841837163196662e-12 11.164827266305107 -0.08241021390549241 DLSSS(ph)PPGPYGQEMYAFR ddPTM_PC-9_Lapatinib_30min_R1 3 DLSSSPPGPYGQEMYAFR 18 0 O43741-2;O43741 O43741-2 PRKAB2 5-AMP-activated protein kinase subunit beta-2 1 DLS(0.01)S(0.06)S(0.882)PPGPY(0.044)GQEMY(0.004)AFR;DLS(0.019)S(0.12)S(0.79)PPGPY(0.07)GQEMY(0.001)AFR;DLS(0.007)S(0.03)S(0.962)PPGPY(0.001)GQEMYAFR 103.46 0.00035291 39836300.0 129380.0 114764.0 127544.0 93996.0 114243.0 124302.0 105712.0 93071.0 121656.0 95176.0 True False 127535.01747461356 114498.27100907904 117057.82465407756 100908.77940146392 107523.45135037982 118985.89322211445 111185.2501072114 97395.41843238982 107953.82018552654 111627.0447859517 1.1425100227204428 1.0257216002504859 1.0486511120897228 0.9039814643033829 0.9632383582003747 1.0659235264202647 0.9960422254339218 0.8725073625226624 0.9670937754603404 1.0 16.768327077335677 -3.494116938980814 0.7954831778345927 0.9672441202520021 2.282663017209135 0.47709251877166126 0.05391361412814297 15.211316410583779 1.4963310868339277 0.020667210521901607 28.170239241317258 0.00032054061143820976 3.494116938980814 1.3154188969571328 DLSSVQTLLTK ddPTM_PC-9_Lapatinib_30min_R1 1 DLSSVQTLLTK 11 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 138.99 0.00049211 2282900.0 15918.0 13392.0 15261.0 12600.0 14401.0 11789.0 15395.0 13967.0 13437.0 14859.0 False True 15691.006400996313 13360.991646802022 14006.29948916358 13526.646032367831 13553.96149345535 11284.811951501242 16192.077771686472 14615.957809040321 11923.583562117119 17427.358351627045 0.9003663139532204 0.7666676370119295 0.8036960741015537 0.7761730584431898 0.7777404480920617 0.6475342805151921 0.9291183118510188 0.8386789044064015 0.6841876618095659 1.0 14.089066281093563 -10.595150541628229 5.6279820228295465 1.0000012525659372 0.7915322583894011 0.3704312866578392 0.08151575731004385 1.2583851264458518e-06 2.0741591220488272e-07 0.0775239204271943 0.018802199310066055 2.540092068345274e-11 10.595150541628229 -0.20846899417653608 DLST(ph)PGLEK ddPTM_PC-9_AZD4547_30min_R2 1 DLSTPGLEK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DLS(0.16)T(0.84)PGLEK 120.06 0.004156 29825000.0 401540.0 440710.0 521220.0 605420.0 565940.0 632770.0 478710.0 663790.0 531180.0 532030.0 True False 529221.3674491505 583160.8889462292 514308.28224090225 465849.77264575823 487368.99983548606 593202.7918698357 521314.26261584996 561216.5078767429 559257.0903745376 513403.7916373289 1.0308092306084784 1.1358718000239802 1.001761752870365 0.9073750140412615 0.9492898334100462 1.1554312639141497 1.0154078935671536 1.0931288724746877 1.0893123492348489 1.0 18.969734425114794 -6.747658469982545 24.996437471418837 1.0730236399061241 1.0066850993150673 0.1872467062713421 0.06823835806717914 450.35830039111147 816879.5354788041 0.024343719699742403 0.024219493027996673 1.787893024675274e-07 6.747658469982545 -0.06633854059105682 DLST(ph)PGLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLSTPGLEK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DLS(0.021)T(0.979)PGLEK 97.734 0.011464 4347400.0 77405.0 78057.0 82337.0 84951.0 86174.0 82275.0 81187.0 76124.0 75005.0 62108.0 True False 90508.1376815627 85805.9830992585 84300.22634481154 80191.47088485802 69288.8233052349 77960.35416314017 73496.37961702104 74125.82566004498 76101.80622948101 73367.68875334247 1.2336239456287812 1.1695336810695072 1.1490102492968475 1.093008001852923 0.9444051527666291 1.0625979295223262 1.0017540536694731 1.0103333895286155 1.037265961659641 1.0 16.16285721729734 -5.793131246112416 1.8769595181682808 1.0118906181948544 1.1990415215821866 0.84256141286731 0.03401019332355413 0.12323644016015228 0.8863775239148208 0.010291259944090615 0.020208754048833055 1.6101589630044818e-06 5.793131246112416 0.1871509033873322 DLST(ph)PGLEK ddPTM_PC-9_Lapatinib_30min_R1 1 DLSTPGLEK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DLS(0.034)T(0.966)PGLEK 131.83 0.002986 33604000.0 730090.0 712750.0 725320.0 659380.0 629140.0 631770.0 635990.0 511580.0 582520.0 472020.0 True False 719678.7827178928 711099.6711662282 665686.9894161661 707873.0048271992 592135.2221368302 604750.6698278011 668918.450277031 535349.8744146094 516910.4633924586 553608.0280728855 1.2999789494077625 1.2844822240775167 1.2024518353417462 1.2786537928131416 1.0695929107062596 1.0923805999218321 1.208288927105234 0.9670197093748208 0.9337120077391735 1.0 19.078505338612608 -6.674843549261495 0.46864682138845726 0.9564849763781343 1.3259872123923924 0.7329779185751881 0.06799742641011307 0.6469953060995748 0.29623826816889975 0.06583756652326168 0.10149639791688495 2.1142505426881693e-07 6.674843549261495 0.369502236014258 DLSTIEPLK ddPTM_PC-9_Lapatinib_30min_R1 1 DLSTIEPLK 9 0 P39687;H0YN26;O95626;O43423 P39687 ANP32A;ANP32D;ANP32C Acidic leucine-rich nuclear phosphoprotein 32 family member A;Acidic leucine-rich nuclear phosphoprotein 32 family member D;Acidic leucine-rich nuclear phosphoprotein 32 family member C 0 102.62 0.014367 2591700.0 26625.0 24017.0 20795.0 24663.0 24306.0 19714.0 21468.0 19118.0 20817.0 21305.0 False True 26245.322617572972 23961.390112100085 19085.315371021345 26476.79929335617 22876.36886743459 18870.878175578546 22579.507996269258 20006.292073690318 18472.370247271872 24987.54086287195 1.0503363560905632 0.9589335038448469 0.7637932630409221 1.0596000398221281 0.9155110137879046 0.7552114983678957 0.9036306581821064 0.8006506996219431 0.7392632331707069 1.0 14.608921305803575 -6.551616475672166 13.559138763220272 0.8317171206239812 0.9497369973166104 0.22695916960553764 0.10281362919339737 2.2839473410821842 1074.8151433634941 0.03321822672900752 0.03324969753146561 2.807912203349714e-07 6.551616475672166 0.11801987669262926 DLSTS(ph)PKPSPIPSPVLGR ddPTM_PC-9_AZD4547_30min_R2 1 DLSTSPKPSPIPSPVLGR 18 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 DLS(0.175)T(0.178)S(0.642)PKPS(0.005)PIPSPVLGR 70.167 0.00485 27774000.0 143520.0 115870.0 91905.0 116060.0 98734.0 94648.0 55317.0 77476.0 67134.0 87421.0 True False 189156.3745985508 153322.71153865292 90686.27965033967 89304.16010912528 85026.48837289613 88729.64559776254 60240.10583677157 65503.86442136614 70682.56618322268 84360.41739888153 2.2422408569194525 1.8174721779018332 1.0749861421565465 1.0586026345373356 1.0078955390994002 1.0517923966428708 0.7140802249938872 0.7764762958870164 0.8378641116604978 1.0 16.36427861287222 -4.88175138435718 1.0297405618413717 0.8769156416205308 2.8687931234450423 0.941296304497974 0.11185070699796533 0.35787220042351825 0.3439151634396505 0.03927397998851872 0.7594172655255568 1.3129512942830093e-05 4.88175138435718 1.9918774818245115 up DLSTSPKPSPIPS(ph)PVLGR ddPTM_PC-9_AZD4547_30min_R2 1 DLSTSPKPSPIPSPVLGR 18 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 DLSTSPKPS(0.012)PIPS(0.987)PVLGR 48.706 0.038169999999999996 21902000.0 50266.0 45708.0 56533.0 71556.0 68084.0 65837.0 48820.0 60556.0 49385.0 56331.0 True False 66249.5424022489 60482.2171313432 55783.33548199397 55059.869729179445 58631.711815385395 61720.20198229101 53164.88542312829 51198.4616384461 51995.39027852426 54358.86883582199 1.2187439477878 1.1126467203358357 1.0262048618133361 1.0128957961850653 1.078604339477124 1.1354210141624208 0.9780351681654774 0.9418603207708176 0.9565208289297548 1.0 15.730227814647957 -1.5228787452803376 0.3890962261100426 0.9889903557788031 4.1930061479344145 0.6049628018660804 0.0527417213324206 56.916720658593974 0.7674834506381415 0.045091253257351936 138.56123446247122 0.029999999999999995 1.5228787452803376 3.2040157921556114 DLSTSPKPSPIPS(ph)PVLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLSTSPKPSPIPSPVLGR 18 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 DLSTSPKPS(0.005)PIPS(0.995)PVLGR 58.755 0.014497 14057000.0 74293.0 62468.0 58749.0 87172.0 80624.0 70937.0 84933.0 60971.0 78174.0 62013.0 True False 86869.33754636427 68669.41020337027 60149.7989668232 82288.03545543729 64826.30596422666 67216.93884254846 76887.53137832951 59370.57585411448 79317.14685932179 73255.4660053621 1.1858410338964422 0.9373964012234097 0.8210963938502608 1.1233023273568967 0.8849347290955947 0.9175689202172076 1.0495808104299214 0.8104593294071559 1.0827471475441297 1.0 16.160648790751512 -4.759121170701618 24.72687007496343 0.9527562590480211 1.1858413846627696 0.31326377427040963 0.10062163559503644 61.740578694533404 658376.9196839121 0.02328132701742234 0.15122124888693655 1.7413209668707195e-05 4.759121170701618 0.23308512561474848 DLSTSPKPSPIPS(ph)PVLGR ddPTM_PC-9_Lapatinib_30min_R1 1 DLSTSPKPSPIPSPVLGR 18 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 DLSTSPKPSPIPS(1)PVLGR 86.959 0.00079776 13082000.0 37937.0 38361.0 47658.0 39336.0 30942.0 37020.0 41113.0 38082.0 51994.0 51923.0 True False 37396.01142320623 38272.17746139279 43739.74320520002 42228.90066104927 29122.052394312588 35436.740897834956 43241.62997254603 39851.428745176025 46137.88819890733 60897.82136695139 0.6140779847914338 0.6284654623484232 0.7182480788867288 0.6934386109905477 0.4782117281147404 0.5819049040244665 0.7100685870515033 0.6543982666480573 0.7576278947795967 1.0 15.894102995869611 -8.772996802668809 1.069401168107729 1.0001296664473085 0.6271490154576067 0.746677453701518 0.06539934044043821 0.48485605427366707 1.048917752875727 0.06782814042732103 0.021552742684645423 1.686565442052246e-09 8.772996802668809 -0.3729806509897018 DLSYCLSGMYDHR ddPTM_PC-9_AZD4547_30min_R2 1 DLSYCLSGMYDHR 13 0 P52597 P52597 HNRNPF Heterogeneous nuclear ribonucleoprotein F;Heterogeneous nuclear ribonucleoprotein F, N-terminally processed 0 147.73 9.3591e-05 4420700.0 36258.0 30923.0 46898.0 69293.0 56533.0 53354.0 37772.0 49224.0 40753.0 49476.0 False True 47787.28978674935 40918.255017776486 46276.10187739116 53318.56941617805 48684.36878061196 50017.76594564079 41133.63482594022 41617.561854991574 42907.12038110155 47743.86029932238 1.000909635022277 0.8570370045749575 0.9692576508742831 1.1167628482888885 1.01969904560279 1.0476271845649372 0.8615481565181277 0.8716840572604944 0.8986939914808381 1.0 15.543027598870987 -7.265538312371808 24.991162634295833 0.8972885547664815 0.9998471210674531 0.2919091738335522 0.07082547720815732 471.3330438980528 2873697.1202373547 0.031132902112654088 0.021868450057703298 5.425773843993477e-08 7.265538312371808 0.1025585663009716 DLTDYLMK ddPTM_PC-9_AZD4547_30min_R2 2 DLTDYLMK 8 0 P60709;A0A2R8Y793;P63267-2;A0A2R8YEA7;Q562R1;P63261;I3L3I0;I3L1U9;I3L4N8;P68133;P68032;P63267;P62736 P60709;P63261;P68133 ACTB;ACTG2;ACTBL2;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 0 ; 133.55 0.016044 45168000.0 311720.0 273160.0 381270.0 391610.0 398380.0 398770.0 342570.0 472920.0 354840.0 344960.0 False True 410840.4758212124 361453.62806505937 376214.11068260716 301330.36481418717 343071.81353935145 373834.8488612507 373058.0663539752 399841.08062048286 373596.1179797824 332883.05539765215 1.2341886111638656 1.0858276569027452 1.1301690025441309 0.90521388796503 1.0306076202332621 1.123021562075843 1.1206880623837436 1.2011457902020415 1.12230440066556 1.0 18.344655909901633 -6.871026957176207 9.150686502602571 1.1268981807316358 1.071129433389007 0.02642765159997218 0.09007698762693774 0.8113699197091502 62.91877380813928 0.032977678766413186 0.029093126964580926 1.3457768174920272e-07 6.871026957176207 -0.05576874734262893 DLTDYLMK ddPTM_PC-9_Lapatinib_30min_R1 2 DLTDYLMK 8 0 P60709;A0A2R8Y793;P63267-2;A0A2R8YEA7;Q562R1;P63261;I3L3I0;I3L1U9;I3L4N8;P68133;P68032;P63267;P62736 P60709;P63261;P68133 ACTB;ACTG2;ACTBL2;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 0 ; 141.47 0.010329999999999999 233080000.0 632990.0 660190.0 743170.0 678280.0 700910.0 713440.0 754120.0 639790.0 655490.0 647630.0 False True 623963.4465238495 658661.3706169521 682069.4313191588 728162.9738757501 659683.8518420805 682927.8343098686 793164.6436625003 669516.9790682268 581661.8135842936 759571.9825872693 0.8214671694425757 0.8671480593233659 0.8979654949829511 0.9586490689078168 0.8684941874699645 0.8990956090608637 1.0442257769445458 0.8814398034899926 0.7657757617691815 1.0 19.53482716595915 -5.002415223199226 1.9522446242604345 0.9148988437455062 0.8143898909215467 0.14837830882941294 0.0719832785876114 1.0204512335460407 5.829202474868479 0.02017750441181301 0.15885950665551973 9.94454178228331e-06 5.002415223199226 -0.10050895282395955 DLTEYLSR ddPTM_PC-9_AZD4547_30min_R2 1 DLTEYLSR 8 0 A0A087WUK2;O14979-3;O14979-2;O14979 A0A087WUK2 HNRNPDL Heterogeneous nuclear ribonucleoprotein D-like 0 104.06 0.017804 4898500.0 33173.0 28746.0 35955.0 62764.0 44071.0 44330.0 32784.0 39425.0 37977.0 38851.0 False True 43721.32395873566 38037.58234133177 35478.21320742036 48294.72949413356 37952.502370833885 41558.038092181625 35701.71248897658 33332.77214637253 39984.386688417864 37490.83831532407 1.1661868852066966 1.0145834035880767 0.9463168817145103 1.288174169058084 1.0123140499454 1.1084851648994767 0.9522783190042404 0.8890911391743416 1.0665108726596433 1.0 15.194250464973768 -7.263842864418605 24.86223336972133 0.9677276728875794 1.084980463452316 0.2388610815989337 0.09752968367122901 291.16775024063446 3011879.5363131026 0.03907930026472633 0.02776647139644278 5.446996993743684e-08 7.263842864418605 0.11725279056473648 DLTEYLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLTEYLSR 8 0 A0A087WUK2;O14979-3;O14979-2;O14979 A0A087WUK2 HNRNPDL Heterogeneous nuclear ribonucleoprotein D-like 0 93.162 0.034239 3640400.0 23197.0 23052.0 19657.0 27825.0 25284.0 19813.0 23636.0 21253.0 20667.0 17477.0 False True 27123.793938365878 25340.450214639386 20125.697429587624 26266.05545986714 20329.78170271266 18773.971401206887 21397.02697017884 20695.131269414887 20969.2157768773 20645.44175214413 1.313790921211407 1.2274113830481568 0.9748252263721833 1.2722447780580566 0.9847104240625567 0.9093518863192704 1.0364044144493374 1.0024068032966937 1.0156825912770573 1.0 14.333535667853283 -2.2876824213996763 0.4496596924465062 0.9890646380349337 4.665090233809448 0.567177484224652 0.0884291497784378 31.720443068110963 0.7617346352281755 0.056086457159542004 98.07640023980667 0.005156055442177157 2.2876824213996763 3.6760255957745147 DLTGQVPT(ph)PVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLTGQVPTPVVK 12 0 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DLT(0.001)GQVPT(0.999)PVVK 107.35 0.0038201999999999997 4149200.0 40637.0 46967.0 43726.0 46672.0 43828.0 51100.0 47318.0 42932.0 33681.0 32241.0 True False 47516.04148266475 51629.573365910466 44768.59367177847 44057.11915266555 35240.21802193053 48420.22604359122 42835.696487346526 41805.08049021406 34173.52090680819 38086.03808038443 1.2475973841746768 1.3556036796723523 1.1754594578015658 1.156778740274285 0.9252791783580243 1.2713379622578604 1.1247086503704444 1.0976484453956648 0.8972716152486515 1.0 15.216974598165637 -1.5228787500597585 0.19638501538698527 0.9689121579204214 2.627048363856811 0.45696306008615295 0.10455316155980918 50.54862555788317 0.6036868379699614 0.20484747314189278 25.648171007640535 0.0299999996698493 1.5228787500597585 1.6581362059363898 DLTSLET(ph)TSEMEAGSPENKK ddPTM_PC-9_Lapatinib_30min_R1 1 DLTSLETTSEMEAGSPENKK 20 1 Q5VYS8-5;Q5VYS8-3;Q5VYS8-2;Q5VYS8-4;Q5VYS8-6;Q5VYS8 Q5VYS8-5 ZCCHC6 Terminal uridylyltransferase 7 1 DLT(0.003)S(0.003)LET(0.36)T(0.36)S(0.116)EMEAGS(0.159)PENKK 58.427 0.0079537 7026300.0 91461.0 79841.0 71103.0 74159.0 75492.0 67437.0 64135.0 64583.0 73457.0 60545.0 True False 90156.74936810667 79656.13306991658 65257.18580551726 79612.90024717191 71051.70898298247 64552.876713325044 67455.5964850348 67583.76195183305 65183.49912349763 71010.12257885867 1.2696323579498845 1.1217574365042995 0.9189842720387841 1.12114861030918 1.0005856405060787 0.9090658397559773 0.9499433888474635 0.9517482789412093 0.9179465793923899 1.0 16.11573707674954 -1.5228787549828535 0.6224473644288088 0.9537180436049731 24.42532795875212 0.7123037713914553 0.06021179958967805 103.5419958419107 0.7404321315564153 0.026805574573854796 3326.259179146542 0.02999999932977395 1.5228787549828535 23.47160991514715 DLTSLETTSEMEAGS(ph)PENKK ddPTM_PC-9_AZD4547_30min_R2 1 DLTSLETTSEMEAGSPENKK 20 1 Q5VYS8-5;Q5VYS8-3;Q5VYS8-2;Q5VYS8-4;Q5VYS8-6;Q5VYS8 Q5VYS8-5 ZCCHC6 Terminal uridylyltransferase 7 1 DLTSLET(0.003)T(0.016)S(0.214)EMEAGS(0.767)PENKK 53.278 0.011447 8166100.0 25726.0 23428.0 31520.0 39636.0 35495.0 41746.0 39226.0 33550.0 34657.0 39139.0 True False 33906.33286595824 31000.642840489843 31102.02420519787 30498.532570095573 30567.131938298393 39135.616020668014 42717.03800916899 28365.61840230309 36488.8982663322 37768.755522984415 0.8977349768732604 0.8208012790261041 0.8234855444540803 0.8075069497996962 0.8093232492051948 1.0361902445224014 1.1310152377981653 0.7510339699977939 0.9661133325964805 1.0 15.204905627441972 -6.749914802089992 24.940630074425453 0.9709442246827631 0.8293527411548355 0.38214415611423413 0.09207062067136514 251.1397654129792 543497.0167055135 0.0318491901121129 0.03158697362608616 1.7786282990008558e-07 6.749914802089992 -0.1415914835279276 DLTTAGAVTQCYR ddPTM_PC-9_AZD4547_30min_R2 1 DLTTAGAVTQCYR 13 0 M0R117;Q02543;M0R3D6;M0R1A7;M0R0P7 M0R117 RPL18A 60S ribosomal protein L18a 0 104.07 0.0055515 0.0 7003.7 9520.9 11110.0 18913.0 16221.0 18031.0 10266.0 15611.0 10593.0 11776.0 False True 9230.730913990199 12598.344733652873 10962.674140854951 14552.90005293717 13968.994144841185 16903.51871960584 11179.654112122795 13198.678655092495 11152.92435396189 11363.725824335432 0.8122979255819934 1.1086456087028695 0.964707729693581 1.2806451227265725 1.2292618073314094 1.4874979369360475 0.9838018168461573 1.1614745778913032 0.9814496166457913 1.0 13.472148308318777 -4.175228464355527 1.103749396272276 1.1641362118855016 1.0097093032429401e-11 0.2671524547134133 0.15830793268531546 7.380605236722386 2.906354983191109 0.04955054432200289 13.853994507739825 6.679924219518648e-05 4.175228464355527 -1.1641362118754046 DLTTAGAVTQCYR ddPTM_PC-9_Lapatinib_30min_R1 2 DLTTAGAVTQCYR 13 0 M0R117;Q02543;M0R3D6;M0R1A7;M0R0P7 M0R117 RPL18A 60S ribosomal protein L18a 0 ; 142.89 0.0003849 21227000.0 37083.0 32018.0 39396.0 39955.0 38085.0 46239.0 37113.0 35617.0 36320.0 35913.0 False True 36554.18961981066 31943.864288180066 36157.012952957775 42893.42398597274 35844.915177990886 44261.46575837356 39034.52954469634 37271.89584625109 32229.25913344451 42120.51419893546 0.8678476584394244 0.7583920779625098 0.8584181280928331 1.0183499608619881 0.8510084897989403 1.0508291885831775 0.9267344021570109 0.8848870094561451 0.7651677513058248 1.0 15.36223542815729 -5.52948824743046 24.79093036912865 0.9261983793242262 0.8119411625460431 0.24494896133781519 0.08291910021324382 191.2691228833764 717409.9854764894 0.022369311000014772 0.03887269725717447 2.9546888450933845e-06 5.52948824743046 -0.11425721677818312 DLVAQAPLKPKT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 DLVAQAPLKPKTPR 14 2 O94776;O94776-2 O94776 MTA2 Metastasis-associated protein MTA2 1 DLVAQAPLKPKT(1)PR 73.36 0.0097539 10608000.0 114170.0 69854.0 92184.0 83755.0 73218.0 71860.0 56688.0 56858.0 62243.0 48845.0 True False 112541.91486378649 69692.25735481709 84604.9873605305 89914.62209848937 68911.46119212652 68786.71531384168 59623.027263485725 59499.83025033392 55232.5378921527 57287.793168128606 1.9645007887369252 1.2165289235401995 1.4768414470466895 1.5695249742751884 1.2028995599443792 1.2007220301184574 1.0407632056711218 1.038612712410014 0.9641240277846953 1.0 15.805940143105582 -1.5228787452803394 0.22191834587529305 0.899001492452812 5.583309053294005 0.711247001672873 0.16116026905990663 28.932189302445437 0.3716435136512928 0.25170413632054955 48.66698783402531 0.029999999999999874 1.5228787452803394 4.684307560841193 DLVFKS(ph)S(ph)LGS(ph)QMLCK ddPTM_PC-9_AZD4547_30min_R2 1 DLVFKSSLGSQMLCK 15 1 X6RAN8;Q9NRD8 X6RAN8 DUOX2 Dual oxidase 2 3 DLVFKS(1)S(1)LGS(1)QMLCK 70.235 0.021758 0.0 3667.4 5187.2 6892.6 15453.0 6595.3 7886.3 6766.1 7484.0 5671.6 8138.6 True False 4833.5569133411855 6863.860958775347 6801.199620455163 11890.549596470051 5679.656438164794 7393.1684143102175 7368.269792327491 6327.519765211216 5971.389197199118 7853.670091197045 0.615451993426485 0.8739685878158867 0.8659899819421285 1.5140118515797893 0.7231850042352759 0.9413647795820975 0.9381944628138091 0.8056767971834662 0.7603310462317838 1.0 12.93915128070681 -7.749948897136458 23.16712092602588 0.8372529549411273 0.9359623554793667 0.015376224819968698 0.2289795818447794 368.6203119724752 743221.2791432155 0.11113341265748122 0.0633130897199255 1.7784886701621987e-08 7.749948897136458 0.0987094005382394 DLVLPTQALPAS(ph)PALK ddPTM_PC-9_AZD4547_30min_R2 2 DLVLPTQALPASPALK 16 0 J3KSZ6;U3KQ35;H3BR06;Q15554 J3KSZ6 TERF2 Telomeric repeat-binding factor 2 1 DLVLPTQALPAS(1)PALK;DLVLPTQALPAS(1)PALK 157.98 4.917e-06 71457000.0 143429.0 124531.0 179937.0 206120.0 196768.0 192644.0 159623.0 192500.0 168165.0 173034.0 True False 189036.43849146838 164783.21041356682 177550.91781125276 158602.218522255 169450.15966291272 180597.94022626322 173829.13776927468 162753.54820993575 177053.85858434814 166976.13232745064 1.1321165238200397 0.9868668540628108 1.063331120061305 0.949849636061914 1.0148166525417557 1.0815793713085853 1.0410418264353187 0.974711450920218 1.060354292056151 1.0 17.349282372143925 -4.7507937806879115 24.95013522277298 1.0200932402249117 1.1321167651469564 0.4140091564693318 0.04029777013720194 454.03842724877126 1064059.9796915362 0.009884297852023948 0.1403422837321445 1.775032132657966e-05 4.7507937806879115 0.1120235249220447 DLVLPTQALPAS(ph)PALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DLVLPTQALPASPALK 16 0 J3KSZ6;U3KQ35;H3BR06;Q15554 J3KSZ6 TERF2 Telomeric repeat-binding factor 2 1 DLVLPTQALPAS(1)PALK;DLVLPTQALPAS(1)PALK;DLVLPT(0.5)QALPAS(0.5)PALK;DLVLPT(0.022)QALPAS(0.978)PALK 218.11 3.4362e-22 69781100.0 115009.0 110448.0 121149.0 141060.0 152519.0 136961.0 141719.0 135785.0 128091.0 107533.0 True False 134477.75216870796 121412.54751459688 124037.65162014117 133156.86552269038 122633.99681680273 129778.52405393925 128294.3503632924 132220.7876261001 129964.08855063556 127027.88166924045 1.0586475221153868 0.9557944753478219 0.9764600494804334 1.0482491227351864 0.9654100753732265 1.0216538475534136 1.0099700056193146 1.0408800484477976 1.023114664613872 1.0 16.954785666954777 -6.900160922322431 24.751271335891044 1.0211153810979916 0.9990621633185318 0.07045748078947278 0.0323268877800237 28.27801379547947 6970.210489156471 0.011081499444470377 0.009772963479458089 1.2584590193331126e-07 6.900160922322431 -0.02205321777945979 DLVLPTQALPAS(ph)PALK ddPTM_PC-9_Lapatinib_30min_R1 2 DLVLPTQALPASPALK 16 0 J3KSZ6;U3KQ35;H3BR06;Q15554 J3KSZ6 TERF2 Telomeric repeat-binding factor 2 1 DLVLPT(0.141)QALPAS(0.859)PALK;DLVLPTQALPAS(1)PALK 128.94 1.9157e-05 53459000.0 165850.0 129614.0 137748.0 125776.0 136902.0 127304.0 109770.0 111741.0 126448.0 107446.0 True False 163484.94858683512 129313.88674646024 126422.8911626566 135025.98661643636 128849.69351968767 121859.50468011822 115453.3534912651 116932.89479057572 112206.09468352946 126017.89793720438 1.2973153120543308 1.026154926111355 1.0032137754404857 1.071482613396081 1.0224713761206714 0.9670015662445162 0.9161663174924273 0.9279070410208257 0.8903980824965241 1.0 16.943269124285038 -1.5228787452803376 0.656060546203191 0.9532095360081403 29.805288115246285 0.7768719748356769 0.05142946969954257 115.11769968940193 0.7260560051540174 0.02331793306423357 4830.439934167405 0.029999999999999995 1.5228787452803376 28.852078579238146 DLVMGS(ph)SPQLK ddPTM_PC-9_AZD4547_30min_R2 1 DLVMGSSPQLK 11 0 Q53LP3 Q53LP3 SOWAHC Ankyrin repeat domain-containing protein SOWAHC 1 DLVMGS(0.5)S(0.5)PQLK 67.08 0.035751 13885000.0 19242.0 35439.0 45376.0 51965.0 43741.0 48540.0 61142.0 62335.0 62092.0 52914.0 True False 25360.555741536537 46893.963702583205 44774.2845918483 39985.27210124675 37668.31717461923 45504.7861266523 66583.51955225128 52702.558065799196 65374.05635666961 51061.49696576813 0.49666690654483503 0.9183820782618485 0.8768697992122165 0.7830806865700211 0.737704912957649 0.8911761078442124 1.3039868297807482 1.0321389147899687 1.2803004267676814 1.0 15.639948213288065 -7.0775088159364135 4.905768511217796 1.154835923672812 0.7810513631908026 0.6432512921010967 0.13733295704331677 0.14203289598279847 6.148661830585391 0.05110012357502019 0.03977094685335792 8.365486141119017e-08 7.0775088159364135 -0.3737845604820095 DLVMGS(ph)SPQLKR ddPTM_PC-9_Lapatinib_30min_R1 1 DLVMGSSPQLKR 12 1 Q53LP3 Q53LP3 SOWAHC Ankyrin repeat domain-containing protein SOWAHC 1 DLVMGS(0.5)S(0.5)PQLKR 89.663 0.010825 4750000.0 43590.0 31852.0 28961.0 29729.0 28864.0 25014.0 20596.0 26728.0 27821.0 20445.0 True False 42968.398606573 31778.248650981062 26579.938372692897 31915.369833036762 27166.276268807374 23944.209530481985 21662.36010299804 27969.88045536117 24687.506011882146 23978.891008749917 1.791926014880913 1.3252593140935982 1.1084723794354734 1.330977726258934 1.1329246318728576 0.9985536662952729 0.9033929090003965 1.1664376156993639 1.0295516169982029 1.0 14.549477317151721 -1.5228787453119088 0.6455725426837208 1.046313590222471 63.274529226447314 0.8236491346496075 0.10203088329372795 90.51539341692721 0.5940565622740507 0.04551347872945611 8041.684630801464 0.029999999997819136 1.5228787453119088 62.228215636224846 DLVQPDKPAS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 DLVQPDKPASPK 12 1 Q6PJT7;Q6PJT7-2;Q6PJT7-9;Q6PJT7-5;H0YJA2;G3V411;G3V4R5 Q6PJT7 ZC3H14 Zinc finger CCCH domain-containing protein 14 1 DLVQPDKPAS(1)PK;DLVQPDKPAS(1)PK 112.02 0.0048419 21441400.0 109432.0 112794.0 74555.0 95675.0 94786.0 95247.0 99564.0 74440.0 100413.0 107496.0 True False 144229.09967299813 149252.45469311142 73566.35198662833 73618.60691401485 81626.60002545569 89291.1900330706 108425.00311897478 62937.00846102653 105720.62618279761 103732.59775923578 1.3903932108955284 1.438819213219046 0.7091922267036679 0.7096959731490022 0.7868943976021087 0.8607823573484219 1.0452355909434574 0.6067235355187368 1.0191649343263924 1.0 16.662509803838617 -5.255688502977058 24.992363605861165 0.8293713858221972 1.414606288638438 0.7293555334822226 0.13929604933600365 215.06583011358623 934633.7837454089 0.03465170037245885 0.08659720526295714 5.550236600603828e-06 5.255688502977058 0.5852349028162409 DLVQPDKPAS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DLVQPDKPASPK 12 1 Q6PJT7;Q6PJT7-2;Q6PJT7-9;Q6PJT7-5;H0YJA2;G3V411;G3V4R5 Q6PJT7 ZC3H14 Zinc finger CCCH domain-containing protein 14 1 DLVQPDKPAS(1)PK;DLVQPDKPAS(1)PK 68.413 0.016313 84501000.0 153809.0 150984.0 99548.0 160393.0 137083.0 129886.0 154903.0 119884.0 113027.0 122572.0 True False 179845.8258337769 165972.69370150598 101921.60185789218 151406.70021112237 110222.57020854912 123074.5495087648 140229.46643939835 116737.17202759779 114679.80604892375 144793.33332058223 1.2420863703412788 1.1462730354720905 0.703910874351037 1.0456745261599696 0.7612406433416993 0.8500014930678433 0.9684801311184738 0.8062330588738764 0.7920240761017284 1.0 17.14363565277816 -5.109860143842876 5.470661838396278 0.8655202532256767 1.219931796239019 0.6185638695777101 0.10412816951602143 0.12367335174927695 5.072427930318628 0.025006727993265507 0.07047972233942403 7.764971322872166e-06 5.109860143842876 0.3544115430133423 DLVQPDKPAS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 DLVQPDKPASPK 12 1 Q6PJT7;Q6PJT7-2;Q6PJT7-9;Q6PJT7-5;H0YJA2;G3V411;G3V4R5 Q6PJT7 ZC3H14 Zinc finger CCCH domain-containing protein 14 1 DLVQPDKPAS(1)PK;DLVQPDKPAS(1)PK 81.992 0.0059447 277130000.0 278836.0 209488.0 160772.0 197063.0 183234.0 172750.0 190128.0 161759.0 154478.0 158167.0 True False 274859.7475077396 209002.9434069046 147553.94675786665 211555.6704028972 172456.53637190445 165361.88519991838 199971.89753655135 169274.9136702625 137079.0609145439 185505.95520571983 1.4816761391995714 1.1266643336335345 0.7954135304941252 1.1404252233751155 0.9296549869822561 0.8914101168155903 1.0779810131420808 0.912503932731121 0.7389469559752292 1.0 17.501105976150022 -4.852750186756241 3.0478259923064317 0.9431297791959503 1.5258646335075525 0.6804904361853342 0.11408564010711027 0.17878997223928866 2.6687210854220766 0.02867306172941107 0.23376148663540594 1.4036208579237147e-05 4.852750186756241 0.5827348543116022 DLVSFPLS(ph)PAVR ddPTM_PC-9_AZD4547_30min_R2 2 DLVSFPLSPAVR 12 0 J3QLB5;E9PI66;Q7KZJ0;J3QKK3;O43502-2;O43502 J3QLB5 RAD51C DNA repair protein RAD51 homolog 3 1 DLVS(0.001)FPLS(0.999)PAVR;DLVS(0.003)FPLS(0.997)PAVR 149.82 5.9204e-05 8304900.0 12600.0 12005.0 17359.6 23155.0 20393.3 20436.0 15379.8 22314.0 14990.2 19283.1 True False 16606.53790371896 15885.381479429758 17129.400361438868 17816.97249118384 17562.042308981545 19158.133689416274 16748.572405379517 18865.88402470913 15782.551368900175 18608.00453831885 0.892440555327771 0.8536853829069911 0.9205393477933035 0.9574896896920856 0.943789661745654 1.0295641131194138 0.9000735339939182 1.013858524478497 0.848159260516069 1.0 14.183635733333134 -5.511152952416036 3.212107693242874 0.9568073514605675 0.8734393841905386 0.2918241013127246 0.0514323480169864 0.28379700409365144 5.996384590340086 0.013262782478124924 0.028301458434960416 3.0821022859515837e-06 5.511152952416036 -0.08336796727002893 DLVSFPLS(ph)PAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLVSFPLSPAVR 12 0 J3QLB5;E9PI66;Q7KZJ0;J3QKK3;O43502-2;O43502 J3QLB5 RAD51C DNA repair protein RAD51 homolog 3 1 DLVS(0.014)FPLS(0.986)PAVR 84.734 0.010048 3056700.0 10826.0 9046.0 13481.0 10831.0 15385.0 10831.0 12488.0 11706.0 9601.2 9210.5 True False 12658.627976753407 9944.027097068705 13802.43816697721 10224.174184575777 12370.419692146588 10263.00329311421 11305.046234709476 11398.729903532236 9741.599386314141 10880.290739722115 1.1634457460349732 0.9139486558722858 1.2685725498664135 0.9396967810105509 1.13695672184423 0.943265537532532 1.0390389838974294 1.0476493851324566 0.8953436649214893 1.0 13.409429487897908 -6.909032209294484 0.736788843472799 0.9759240251887623 1.085896469356018 0.14557999481789452 0.10720279645269108 1.4645185720735405 1.6993910803996368 0.07602684555766691 0.0651543331091252 1.2330133838424224e-07 6.909032209294484 0.10997244416725571 DLVSFPLS(ph)PAVR ddPTM_PC-9_Lapatinib_30min_R1 2 DLVSFPLSPAVR 12 0 J3QLB5;E9PI66;Q7KZJ0;J3QKK3;O43502-2;O43502 J3QLB5 RAD51C DNA repair protein RAD51 homolog 3 1 DLVSFPLS(1)PAVR;DLVSFPLS(1)PAVR 147.26 0.00013363 7510500.0 15237.7 14462.9 16472.6 12105.0 11183.2 11154.6 11941.5 10892.0 13803.5 9992.5 True False 15020.407603748052 14429.41204364792 15118.286414074833 12995.242081096238 10525.426163017139 10677.543760642613 12559.772439791752 11398.082083200916 12248.804472701024 11719.690310830692 1.2816386103536386 1.231211035526515 1.2899902653659154 1.1088383512221949 0.898097636017747 0.9110772961957037 1.071681256644188 0.9725582998270386 1.045147452521109 1.0 13.516646827045802 -5.960019037755726 3.834914737130974 0.9829833743141821 1.262211890006967 0.8551782814427102 0.052357846586392184 0.08107248673521375 2.551759593471897 0.01604891339302299 0.02396479590847954 1.0964301319208529e-06 5.960019037755726 0.27922851569278484 DLYANT(ph)VLSGGTTMYPGIADR ddPTM_PC-9_AZD4547_30min_R2 1 DLYANTVLSGGTTMYPGIADR 21 0 P60709;A0A2R8Y793;P63261 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 DLYANT(0.996)VLS(0.001)GGT(0.001)T(0.001)MY(0.001)PGIADR 87.49600000000001 0.0016945999999999999 5562300.0 21212.0 18635.0 23780.0 35817.0 25207.0 24588.0 17222.0 29599.0 17381.0 24042.0 True False 27956.974762990987 24658.39932271332 23464.661662424023 27559.944017133756 21707.443154491833 23050.50847305574 18754.72463656524 25025.154667355248 18299.724175985222 23200.296897815275 1.2050265945356777 1.062848438160951 1.011394887133261 1.1879134193204666 0.9356536793516629 0.9935436850045811 0.8083829581651316 1.0786566558858053 0.7887711203259847 1.0 14.50185564741372 -6.281139713042449 23.554052827218324 0.9347803441414816 1.1054138007379708 0.4607304778629715 0.09647960936767827 357.1222796025453 426980.0337781087 0.028252023294575875 0.03209152647991 5.234320208045252e-07 6.281139713042449 0.1706334565964892 DLYANT(ph)VLSGGTTMYPGIADR ddPTM_PC-9_Lapatinib_30min_R1 1 DLYANTVLSGGTTMYPGIADR 21 0 P60709;A0A2R8Y793;P63261 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 DLY(0.036)ANT(0.948)VLS(0.007)GGT(0.007)T(0.001)MY(0.001)PGIADR 100.41 0.00076528 3867900.0 22407.0 20401.0 28545.0 20288.0 23879.0 23598.0 19212.0 18541.0 20723.0 14745.0 True False 22087.47207105945 20353.762737933717 26198.140286886457 21780.047198784017 22474.484167920302 22588.768549624776 20206.703354962036 19402.482547248277 18388.957517135754 17293.65360352249 1.2772010228399926 1.176949834000834 1.51489910041625 1.2594242777216094 1.2995798738181357 1.306188331713996 1.1684461721175101 1.1219423605950016 1.0633355992160134 1.0 14.077955076687092 -7.71630607224912 1.0856951431002553 1.016059632154081 1.3134846982834139 0.6566079650169167 0.08132669626632778 0.3249107136451755 0.6945220081479283 0.07003933656918662 0.02859572548615061 1.921736893258088e-08 7.71630607224912 0.29742506612933295 DLYANTVLS(ph)GGTTMYPGIADR ddPTM_PC-9_AZD4547_30min_R2 1 DLYANTVLSGGTTMYPGIADR 21 0 P60709;A0A2R8Y793;P63261 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 DLYANT(0.012)VLS(0.419)GGT(0.419)T(0.122)MY(0.027)PGIADR 145.61 0.00041989 3753200.0 23277.0 22148.0 33549.0 37427.0 32322.0 30928.0 23741.0 35206.0 22696.0 27047.0 True False 30678.60180832273 29306.907872254076 33104.118339472814 28798.783391385776 27834.648218331607 28994.06727080966 25853.90300758885 29765.72165339739 23895.664225197677 26100.092762466098 1.1754211790557647 1.1228660426218722 1.2683525166270302 1.1033977409000093 1.0664578272441978 1.1108798552817911 0.9905674758661668 1.1404450522184635 0.9155394366858897 1.0 14.671767313843153 -6.752012661194361 0.5783759372076593 0.9941398084428138 1.1916667115655275 0.5222165847954183 0.06641479862569222 0.740351424328269 0.5382502243454994 0.053785195290739815 0.06338078117709045 1.77005735423814e-07 6.752012661194361 0.1975269031227137 DLYANTVLS(ph)GGTTMYPGIADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLYANTVLSGGTTMYPGIADR 21 0 P60709;A0A2R8Y793;P63261 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 DLYANT(0.047)VLS(0.642)GGT(0.205)T(0.104)MY(0.002)PGIADR 136.33 3.4171e-10 0.0 13988.0 13779.0 14571.0 18272.0 17755.0 11376.0 15641.0 17654.0 16347.0 10098.0 True False 16355.892124406675 15146.888057761418 14918.42790082523 17248.27907862328 14276.03520533395 10779.422533696552 14159.37124896628 17190.601205959163 16586.04394951437 11928.687464275985 1.3711392953658377 1.2697866469486518 1.2506344847664854 1.4459494500361754 1.1967817287599998 0.903655374154009 1.1870016119854547 1.4411142263087662 1.3904332726619109 1.0 13.542147688889903 -6.393170935161081 13.34982905418978 1.194199902229141 1.3237582859189645 0.17298500395858796 0.1571914935477072 1.7384626575201136 176.95947328728667 0.053318370710936126 0.06045447221797128 4.044166848914973e-07 6.393170935161081 0.12955838368982353 DLYANTVLS(ph)GGTTMYPGIADR ddPTM_PC-9_Lapatinib_30min_R1 1 DLYANTVLSGGTTMYPGIADR 21 0 P60709;A0A2R8Y793;P63261 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 DLYANTVLS(0.572)GGT(0.128)T(0.128)MY(0.171)PGIADR 86.803 0.00039524 4689900.0 14756.0 15760.0 18755.0 15116.0 16854.0 18607.0 14318.0 16512.0 14885.0 11565.0 True False 14545.576734081022 15723.508688291518 17213.036296393606 16227.68106549778 15862.680856238914 17811.221985035525 15059.315981487951 17279.207800019598 13208.494554001136 13563.99484060615 1.0723667256593417 1.1592092796452924 1.2690240964161548 1.1963791829909451 1.169469691093604 1.3131250928903755 1.1102419426174728 1.273902563593678 0.9737908860344916 1.0 13.727494520261546 -8.272370057690965 24.939471630738222 0.9868953904542412 1.1969535002358485 0.581030690569809 0.07083481466979835 533.8168848269571 1217944.3187066347 0.06371814131591497 0.01708483059434033 5.341090568207788e-09 8.272370057690965 0.21005810978160722 DLYANTVLSGGT(ph)TMYPGIADR ddPTM_PC-9_AZD4547_30min_R2 1 DLYANTVLSGGTTMYPGIADR 21 0 P60709;A0A2R8Y793;P63261 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 DLYANT(0.004)VLS(0.196)GGT(0.735)T(0.065)MYPGIADR 136.46 2.9479e-10 0.0 3839.0 5063.9 5126.3 5744.1 6145.4 4557.0 4517.5 6668.8 3152.4 5487.2 True False 5059.722143839451 6700.706645038266 5058.321912535082 4419.886490460338 5292.2172873255095 4272.050069615873 4919.548748442889 5638.290193778802 3319.0294282478458 5295.094798173693 0.955548925315667 1.2654554640550302 0.9552844859887543 0.8347133826545997 0.9994565704755323 0.8067938785702811 0.9290766144809471 1.0648138340645912 0.6268120883109775 1.0 12.37044079770516 -5.500613844849797 19.792867258999973 0.8990436669243362 1.1104700995837191 0.2834562182801874 0.13543859624397184 61.4119123280004 54590.608978432654 0.03308592503002339 0.06744288299161863 3.1578111593401443e-06 5.500613844849797 0.21142643265938288 DLYANTVLSGGT(ph)TMYPGIADR ddPTM_PC-9_Lapatinib_30min_R1 1 DLYANTVLSGGTTMYPGIADR 21 0 P60709;A0A2R8Y793;P63261 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 DLYANTVLS(0.025)GGT(0.853)T(0.121)MYPGIADR 189.98 7.8418e-15 4975000.0 26353.0 29237.0 36174.0 29676.0 27726.0 31150.0 31204.0 25187.0 32789.0 22165.0 True False 25977.201387451674 29169.303522815924 33199.91335567808 31858.472036233932 26095.211191413313 29817.78711419659 32819.59043765539 26357.279969664116 29095.957536522885 25996.190716993988 0.9992695341502514 1.1220606834426567 1.2771068545044542 1.2255053974276204 1.0038090378508646 1.1470060147967904 1.262476906518495 1.0138900832280047 1.119239270602156 1.0 14.66601261679062 -8.442501800832622 1.1726294211863213 1.0072559832040124 1.1456807162316405 0.146062018320251 0.09713714705420597 0.9188998086995983 2.747432556729137 0.0949891406195964 0.030193900031868334 3.60992516702447e-09 8.442501800832622 0.13842473302762803 DLYANTVLSGGTT(ph)MYPGIADR ddPTM_PC-9_Lapatinib_30min_R1 2 DLYANTVLSGGTTMYPGIADR 21 0 P60709;A0A2R8Y793;P63261 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 DLYANTVLS(0.005)GGT(0.09)T(0.776)MY(0.129)PGIADR;DLY(0.025)ANT(0.069)VLS(0.002)GGT(0.077)T(0.815)MY(0.012)PGIADR 144.18 0.00020314 5182000.0 30208.0 29178.0 38876.0 38353.0 31270.0 38259.0 33748.0 30103.0 34551.0 27667.0 True False 29777.228380531247 29110.44013369099 35679.76534569971 41173.60756185741 29430.76007918539 36622.751756085025 35495.30630976782 31501.695276404418 30659.502541840327 32449.20408603979 0.9176566642921737 0.897107986269987 1.099557488408468 1.268863404251293 0.9069794131513695 1.1286178748476843 1.0938729410943706 0.9708002449883507 0.9448460572575516 1.0 14.985895471789101 -10.588555234185344 14.698626687787542 1.0000036591721624 1.0309031051969197 0.002293161438794211 0.1148708168753937 0.0 0.0 0.11557150924939377 0.028030208232194063 2.578960947674815e-11 10.588555234185344 0.03089944602475736 DLYANTVLSGGTTMYPGIADR ddPTM_PC-9_AZD4547_30min_R2 4 DLYANTVLSGGTTMYPGIADR 21 0 P60709;A0A2R8Y793;P63261 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ;;; 174.18 8.7465e-12 34999300.0 95240.0 76809.0 125601.0 154938.0 134791.0 117043.0 102113.0 133595.0 94472.0 111594.0 False True 125524.3388849358 101636.00716814001 123935.44867376443 119219.43786823752 116077.59631202088 109724.28270749385 111200.85918090733 112950.96245769566 99465.5970515895 107687.12802657014 1.1656392104167232 0.9438083179547968 1.1508845202296163 1.1070908849832264 1.0779152387031858 1.018917346188498 1.03262907293312 1.0488808135901513 0.9236535403474397 1.0 16.716486287531033 -7.460177769971258 0.9046490268322355 0.9764524111334181 1.0850208810968787 0.321952545149073 0.06298317102151858 0.7671614616453261 1.17257677434794 0.05086068391968925 0.025527869264126958 3.465949495332582e-08 7.460177769971258 0.10856846996346059 DLYANTVLSGGTTMYPGIADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DLYANTVLSGGTTMYPGIADR 21 0 P60709;A0A2R8Y793;P63261 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ;;; 203.92 2.6775e-23 45429000.0 103817.6 111435.09999999999 103478.7 126888.3 144923.19999999998 131289.2 128287.5 113524.3 101057.9 109835.8 False True 121391.8691889335 122497.64027908021 105946.02465315492 119779.15992841897 116526.53929989603 124404.16323057248 116135.17927893091 110544.40741393829 102535.68060473638 129748.16108028531 0.9355960668592357 0.9441185081866507 0.8165512618525502 0.9231665322354916 0.898097809862538 0.9588125349506411 0.8950815049091063 0.8519920937109532 0.7902669274926336 1.0 16.985354565858863 -7.570810107418202 6.646238111201145 0.866805857772633 0.9109846712348233 0.038451826188628524 0.06086586715880101 0.5019743230767519 51.896798106883715 0.02806523737097211 0.016139957577413426 2.686518852676142e-08 7.570810107418202 0.044178813462190325 DLYANTVLSGGTTMYPGIADR ddPTM_PC-9_Lapatinib_30min_R1 5 DLYANTVLSGGTTMYPGIADR 21 0 P60709;A0A2R8Y793;P63261 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ;;;; 226.79 1.8101999999999997e-40 155551500.0 324799.0 287394.6 338105.7 305468.0 326393.3 320467.6 287798.4 278262.8 292773.9 289011.5 False True 320167.3066991576 286729.1554611721 310307.95447174454 327933.1357313756 307195.4878079177 306761.9477944628 302699.19294361403 291191.9055362939 259798.6203361558 338966.7526913829 0.9445389677808858 0.8458916787105335 0.9154524802444823 0.9674492649429456 0.9062702621091816 0.9049912575755138 0.8930055544981748 0.8590574244354099 0.7664427802236201 1.0 18.370784249038756 -7.558412830056636 2.9424780943108533 0.8601280265833636 0.9128680052711365 0.06060719810518411 0.060780105443656404 0.561976519478088 9.913526423128312 0.031059104613291887 0.01692231789929732 2.7643127058666748e-08 7.558412830056636 0.052739978687772915 DLYDAGVK ddPTM_PC-9_AZD4547_30min_R2 2 DLYDAGVK 8 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YN28;H0YNP5;H0YL33 P07355 ANXA2 Annexin A2;Annexin 0 ; 119.27 0.015972 21499800.0 160512.0 172767.0 196734.0 223190.0 240040.0 214178.0 193851.0 233580.0 191585.0 217432.0 False True 211551.47714299537 228610.55410717556 194125.17861628806 171736.99375112588 206714.58939200308 200785.41580210364 211103.36346085306 197485.57813442446 201711.79197147055 209819.77186114978 1.008253298850175 1.0895567757001507 0.9251996458405847 0.8184976669633139 0.9852007156351233 0.956942303487849 1.006117591246609 0.9412152934048199 0.9613574077516166 1.0 17.67879110765231 -5.268242976540134 24.80769508128563 0.946127335284601 1.0489050389679615 0.3570122661881062 0.05332288691194759 464.0281416241156 1691974.9195894548 0.014486544744822125 0.03132489091382012 5.392088646839099e-06 5.268242976540134 0.10277770368336048 DLYDAGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DLYDAGVK 8 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YN28;H0YNP5;H0YL33 P07355 ANXA2 Annexin A2;Annexin 0 ; 119.27 0.015972 16094600.0 138603.0 167347.0 153731.0 159065.0 179500.0 132415.0 149681.0 134775.0 143624.0 134749.0 False True 162065.75036596647 183960.10420220616 157396.5300680644 150153.10374568764 144328.26355153156 125470.92429671498 135502.13208340394 131237.29905591637 145724.22929008672 159177.92702750262 1.0181421092257652 1.155688528161456 0.9888087689499159 0.9433035506219674 0.9067102848160263 0.7882432359797991 0.8512620726615695 0.8244692056659421 0.9154801297601307 1.0 17.280280767756956 -5.7731113475655675 1.614685177767496 0.865975714386232 1.0874587090663586 0.5994620932300971 0.06471991046915819 0.22889713520699387 1.2115263447026563 0.02005918325707757 0.0433470615360751 1.686120670133216e-06 5.7731113475655675 0.22148299468012655 DLYDAGVK ddPTM_PC-9_Lapatinib_30min_R1 4 DLYDAGVK 8 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YN28;H0YNP5;H0YL33 P07355 ANXA2 Annexin A2;Annexin 0 ;;; 133.55 0.017289 80305800.0 923360.0 793771.0 922634.0 898456.0 812608.0 720673.0 906271.0 809025.0 789504.0 907538.0 False True 910192.7170765159 791933.0720186438 846778.5939902319 964531.4514013571 764811.9950887976 689851.4957608156 953193.2779619396 846615.254990966 700581.7456743103 1064404.7340816285 0.8551190049542882 0.744014984771677 0.7955419276867788 0.906169824802177 0.7185349431470536 0.6481101348689711 0.8955176987110617 0.7953884719626205 0.6581911215180514 1.0 20.021615401389298 -10.807897549314985 4.6345718318555615 1.0001063812765467 0.7809718330355024 0.3753811734580149 0.08526706898901448 9.393460670244142e-05 1.4491427461314777e-05 0.08274309958478324 0.020058433309870307 1.556332729404913e-11 10.807897549314985 -0.21913454824104428 DLYDAGVKR ddPTM_PC-9_AZD4547_30min_R2 1 DLYDAGVKR 9 1 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YN28;H0YNP5;H0YL33 P07355 ANXA2 Annexin A2;Annexin 0 74.173 0.017601 24065000.0 128880.0 132420.0 177210.0 251510.0 234120.0 176440.0 166500.0 215810.0 188470.0 220200.0 False True 169861.1591294681 175222.17538576326 174860.07961304294 193528.25529076456 201616.47920536506 165407.1789078392 181318.1774467606 182461.52332044797 198432.139430869 212490.86502366405 0.7993809950867842 0.8246103914455317 0.8229063380845555 0.9107603532472432 0.9488242197278082 0.77842018709566 0.8532986932241444 0.8586793756998831 0.9338384471669904 1.0 17.69704129560086 -14.522878745268764 0.12575596181224777 1.4808154308406432 0.7943472575364001 0.4916076110360532 0.04878547178169166 143.6938167289749 1.1492781204821887 17.349951164404516 0.44183058006879844 3.000000000079944e-15 14.522878745268764 -0.686468173304243 DLYDAGVKR ddPTM_PC-9_Lapatinib_30min_R1 3 DLYDAGVKR 9 1 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YN28;H0YNP5;H0YL33 P07355 ANXA2 Annexin A2;Annexin 0 ;; 95.35799999999999 0.0034497 59678000.0 564660.0 429074.0 396978.0 406575.0 427310.0 367928.0 386590.0 345347.0 471510.0 357478.0 False True 556607.8448540374 428080.5055152279 364340.0012193954 436475.8817944395 402176.4659237831 352192.5771220584 406605.738600602 361393.0823712065 418403.57857958245 419267.5959905072 1.3275718185162102 1.0210197725963068 0.8689915574292189 1.0410436818120377 0.9592357476939116 0.8400185954986908 0.9698000572641634 0.8619628271472449 0.9979392220644108 1.0 18.677511807100707 -4.782913749497977 3.241830476535206 0.938775352460328 1.382065197550045 0.7685762309587683 0.06319291232926375 0.14479809802427862 2.3493720954156916 0.015470650886514706 0.16355620316906097 1.648489747631688e-05 4.782913749497977 0.44328984508971714 DLYLENPEIK ddPTM_PC-9_Lapatinib_30min_R1 1 DLYLENPEIK 10 0 P21980 P21980 TGM2 Protein-glutamine gamma-glutamyltransferase 2 0 97.456 0.023673 4548300.0 35886.0 35287.0 36448.0 30087.0 33188.0 26681.0 33288.0 29890.0 29276.0 33415.0 False True 35374.259059313576 35205.29511952682 33451.386133348664 32299.69834728974 31235.947090118472 25539.915826448792 35011.48976056508 31278.79851880972 25978.628590052907 39190.73822731127 0.9026178290936592 0.8983065058721688 0.8535533558803197 0.8241666222245517 0.7970236975110294 0.6516824377819583 0.8933613232160614 0.7981171045410961 0.6628767347880399 1.0 15.258225128474518 -5.664392056022487 1.705117559922313 0.7889789271292345 0.9021511221363966 0.1388588822489778 0.09519812789319243 0.6557141770698519 3.820302338959657 0.028566659922579486 0.06836143148493416 2.165748109528238e-06 5.664392056022487 0.11317219500716214 DLYPFTVNT(ph)SNQGSR ddPTM_PC-9_AZD4547_30min_R2 2 DLYPFTVNTSNQGSR 15 0 Q96BY6;A0A2R8YD85;Q96BY6-3;H7C0I3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 DLY(0.013)PFT(0.011)VNT(0.475)S(0.475)NQGS(0.027)R;DLYPFT(0.002)VNT(0.499)S(0.499)NQGSR 127.2 5.2458000000000005e-05 7777300.0 20639.4 33409.0 30358.0 32171.0 30300.0 31222.0 34693.0 38884.0 28068.0 25235.0 True False 27202.29987381087 44207.80590139683 29955.433084435183 24754.472986995286 26093.368016071014 29269.68340433326 37780.60979075357 32875.37126542929 29551.617178042325 24351.530330936217 1.1170673671893643 1.8154015497430638 1.2301252807253662 1.0165469130926514 1.0715288797649798 1.2019648460100685 1.551467578313016 1.3500330705567352 1.2135425074497233 1.0 14.571724818447555 -5.471915754193502 24.991547205982897 1.2168041955936562 1.480366935488213 0.183247688163929 0.21964222787868565 565.6480148125479 277384.6354920285 0.058080539597697586 0.12090199478989763 3.3735274305585337e-06 5.471915754193502 0.2635627398945568 DLYPFTVNT(ph)SNQGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DLYPFTVNTSNQGSR 15 0 Q96BY6;A0A2R8YD85;Q96BY6-3;H7C0I3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 DLYPFT(0.099)VNT(0.442)S(0.442)NQGS(0.018)R 94.339 0.01084 0.0 13758.0 24361.0 20899.0 13559.0 20404.0 14509.0 16000.0 14029.0 11387.0 9670.0 True False 16086.957667113742 26779.399083759778 21397.311419898873 12799.333188871115 16405.982671339552 13748.12249836526 14484.364170031364 13660.753614954177 11553.51333291247 11423.094452322115 1.408283695303206 2.344320901445054 1.8731624350308314 1.1204786270737028 1.4362117672943258 1.2035374964067207 1.2679895303751907 1.195889053703586 1.0114171235416725 1.0 13.479665901203001 -5.741233490534228 8.440729421351685 1.2002575174662242 1.924600279092683 0.6331601874875876 0.24241263195241866 0.115484246873034 38.992147861871146 0.06319093191765736 0.10654824955051283 1.8145398461153736e-06 5.741233490534228 0.7243427616264588 DLYPFTVNT(ph)SNQGSR ddPTM_PC-9_Lapatinib_30min_R1 1 DLYPFTVNTSNQGSR 15 0 Q96BY6;A0A2R8YD85;Q96BY6-3;H7C0I3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 DLYPFT(0.009)VNT(0.496)S(0.496)NQGSR 151.49 0.00035486 3590700.0 9143.6 22351.0 17789.0 14270.0 17326.0 18338.0 17135.0 17152.0 15654.0 12077.0 True False 9013.210587269125 22299.24763274134 16326.45708752579 15319.463403324526 16306.9187442266 17553.726487965894 18022.16645780108 17948.944536454463 13890.881676072137 14164.493358409043 0.6363242481890993 1.5743060530649289 1.1526326197776253 1.081539806309402 1.1512532309915384 1.23927669305198 1.2723481173509004 1.2671787181006868 0.980683270808661 1.0 13.789991379261739 -8.275502669068075 23.406891407400607 0.9903414916533038 1.186531164235271 0.09543306995150858 0.2198524727211002 837.8156166323292 1394426.778650787 0.1928630579737317 0.050987866610627465 5.302703337069232e-09 8.275502669068075 0.19618967258196718 DMAECSTPLPEDCS(ph)PTHSPR ddPTM_PC-9_AZD4547_30min_R2 2 DMAECSTPLPEDCSPTHSPR 20 0 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7 Q12802-2 AKAP13 A-kinase anchor protein 13 1 DMAECSTPLPEDCS(0.985)PT(0.014)HSPR;DMAECSTPLPEDCS(0.861)PT(0.117)HS(0.021)PR 97.152 0.00031828 26661000.0 36786.9 33808.3 45955.0 74953.0 48539.0 50582.0 37462.0 58130.0 40910.0 53158.0 True False 48484.368984945955 44736.17181765974 45345.60667353642 57673.743862306255 41800.197694127746 47419.09954384685 40796.04542648979 49147.34419451201 43072.419080579704 51296.95460003592 0.9451705147601882 0.8721019048103182 0.8839824318441054 1.1243112639335098 0.814867042693768 0.9244037957725788 0.7952917623390693 0.9580947753665984 0.8396681521625758 1.0 15.646585557938458 DMAECSTPLPEDCS(ph)PTHSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DMAECSTPLPEDCSPTHSPR 20 0 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7 Q12802-2 AKAP13 A-kinase anchor protein 13 1 DMAECS(0.047)T(0.283)PLPEDCS(0.558)PT(0.109)HS(0.004)PR;DMAECSTPLPEDCS(0.915)PT(0.082)HS(0.003)PR 93.712 0.00042081 17575500.0 26716.1 30802.0 26588.5 37913.0 53672.0 31110.0 52287.0 39973.0 36685.0 28335.0 True False 31238.608062972635 33859.81899667373 27222.47067744777 35788.85752560443 43155.3568876758 29478.53683397498 47333.99683490185 38923.75110489439 37221.44872379853 33471.91120026343 0.9332782904469101 1.011589054299572 0.813292988099034 1.0692206163991844 1.2893006506104785 0.8806947609774664 1.4141408463861282 1.162878058322169 1.1120204191837602 1.0 15.030663308835686 -5.975827005234577 9.046082156028122 1.154260806310416 0.9302439891524645 0.3241197132398079 0.14372742687961215 0.29124333535290475 98.62800503832146 0.03903530021997289 0.05749729518668753 1.0572385606479966e-06 5.975827005234577 -0.22401681715795152 DMAECSTPLPEDCS(ph)PTHSPR ddPTM_PC-9_Lapatinib_30min_R1 1 DMAECSTPLPEDCSPTHSPR 20 0 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7 Q12802-2 AKAP13 A-kinase anchor protein 13 1 DMAECSTPLPEDCS(0.896)PT(0.091)HS(0.014)PR 114.21 1.2105999999999999e-05 4131000.0 7232.2 13385.0 19821.0 12937.0 15946.0 17336.0 14912.0 10865.0 19815.0 14314.0 True False 7129.067501776953 13354.007854871952 18191.39389127262 13888.430136566874 15008.087631042226 16594.579692189807 15684.070395023622 11369.827564632573 17583.226038799636 16788.155827793908 0.42464863770053335 0.7954422148478932 1.0835850034913042 0.8272755077465779 0.8939688066389841 0.9884694818424533 0.9342342634834019 0.6772529205268079 1.0473589963758518 1.0 14.03515613905473 -4.808868228170327 3.4819438431472847 0.9183338671235872 0.3792796612526847 0.650835246418032 0.11141383720940999 0.1635044227760665 3.2935794392753497 0.027287481140619532 0.22414905836074922 1.5528581002478107e-05 4.808868228170327 -0.5390542058709025 DMDEPS(ph)PVPNVEEVTLPK ddPTM_PC-9_AZD4547_30min_R2 2 DMDEPSPVPNVEEVTLPK 18 0 F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 F8VXC8 SMARCC2 SWI/SNF complex subunit SMARCC2 1 DMDEPS(1)PVPNVEEVTLPK;DMDEPS(1)PVPNVEEVTLPK 97.214 0.00069263 18608000.0 21402.9 25866.6 27389.8 26022.6 33927.6 30628.8 22309.9 30691.2 26168.3 30179.4 True False 28208.576992024322 34227.4726010677 27026.593355822613 20023.491615162202 29217.33837300498 28713.57629410811 24295.43787999691 25948.58025361446 27551.502914356744 29122.82839189442 0.9686070532859179 1.175279823116151 0.9280208979751692 0.6875531231278078 1.003245219861161 0.9859473780403755 0.8342403269717755 0.8910048125969993 0.9460448876601898 1.0 14.82986285558074 -5.41562684089654 7.39710527114529 0.8992949632369894 1.0699883351396056 0.29398901545744216 0.10059851236796086 0.29724750987118614 18.125263323559768 0.026133508486610633 0.05468910301377552 3.840370801765374e-06 5.41562684089654 0.17069337190261613 DMDEPS(ph)PVPNVEEVTLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DMDEPSPVPNVEEVTLPK 18 0 F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 F8VXC8 SMARCC2 SWI/SNF complex subunit SMARCC2 1 DMDEPS(1)PVPNVEEVTLPK;DMDEPS(1)PVPNVEEVTLPK;DMDEPS(0.983)PVPNVEEVT(0.017)LPK 117.53 9.6006e-05 29939800.0 34222.4 44743.3 38680.0 39257.0 44740.0 32866.1 44066.4 35258.2 29302.6 27914.399999999998 True False 40015.57639678975 49185.11912583183 39602.27789471687 37057.55756291122 35973.5181687773 31142.543858537607 39892.1115788919 34332.70960915089 29731.095089927163 32975.05974973117 1.213510352990823 1.491585443639198 1.200976683447548 1.123805622921224 1.0909310988912029 0.9444272154439841 1.209766165145982 1.041172021210084 0.9016236912252918 1.0 15.009087653144928 -5.700832211744408 1.9441349906097682 1.0405869942308479 1.3539074448292958 0.5937481301632455 0.10304877282054647 0.22441664029825112 1.7207674826368657 0.030703488109163887 0.06544101451641153 1.991442577721226e-06 5.700832211744408 0.31332045059844793 DMDEPS(ph)PVPNVEEVTLPK ddPTM_PC-9_Lapatinib_30min_R1 4 DMDEPSPVPNVEEVTLPK 18 0 F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 F8VXC8 SMARCC2 SWI/SNF complex subunit SMARCC2 1 DMDEPS(1)PVPNVEEVTLPK;DMDEPS(1)PVPNVEEVTLPK;DMDEPS(0.998)PVPNVEEVT(0.002)LPK;DMDEPS(0.96)PVPNVEEVT(0.04)LPK 98.035 0.0013120999999999999 18286900.0 98887.4 120368.3 126193.8 101380.4 137838.7 139114.5 129581.3 133658.7 129334.1 108038.0 True False 97477.24754227189 120089.5945967564 115818.63288615485 108836.25281110048 129731.29866731093 133164.89712673854 136290.38566782977 139868.97114707378 114767.13170954907 126712.22434841366 0.7692805334570092 0.9477348788902373 0.914028883019958 0.8589246489102693 1.0238262277725936 1.050923837944651 1.075589875946614 1.1038317089476999 0.9057305425716479 1.0 16.951196187203657 -6.290437998511412 7.2646198333012695 1.0358767791497252 0.8807910005605387 0.5652081933675895 0.06578687477233648 0.16014510736740997 32.45271763355892 0.020067799795918564 0.023174534522045386 5.123444092288803e-07 6.290437998511412 -0.15508577858918648 DMDRDVDR ddPTM_PC-9_AZD4547_30min_R2 2 DMDRDVDR 8 1 H0YIQ2;P49750-3;P49750-1;P49750 H0YIQ2 YLPM1 YLP motif-containing protein 1 0 ; 101.6 0.0058798 13300500.0 34236.0 36894.0 40369.0 60323.0 51307.0 42393.0 37995.0 49100.0 45346.0 40886.0 False True 45122.33584696209 48819.263998507406 39833.68068336396 46416.46433105953 44183.90867328568 39742.15900838833 41376.48139393195 41512.723205755035 47742.89698430624 39454.59358472983 1.1436522784111467 1.237353108039668 1.0096081866315523 1.176452729930645 1.1198672868952386 1.0072885156715894 1.0487113827462147 1.0521645120131655 1.2100719497154886 1.0 15.267905658396678 -5.253384348846869 24.992604064109074 1.0813206465501801 1.1905026936560708 0.2846586197947556 0.07117071753258958 773.243780051959 2399154.718824172 0.01788542955274931 0.04557886314825703 5.57976169527474e-06 5.253384348846869 0.10918204710589063 DMDRDVDR ddPTM_PC-9_Lapatinib_30min_R1 2 DMDRDVDR 8 1 H0YIQ2;P49750-3;P49750-1;P49750 H0YIQ2 YLPM1 YLP motif-containing protein 1 0 ; 85.161 0.017414 13182900.0 71483.0 51324.0 55791.0 44117.0 53908.0 51425.0 49450.0 49352.0 55631.0 45148.0 False True 70463.63931162332 51205.16243133717 51204.07933948794 47361.51134999773 50737.23742720583 49225.672627530046 52010.27903929172 51645.07408833379 49365.25095959943 52951.77164407144 1.3307135365604437 0.9670150939523886 0.9669946396443342 0.8944273228165047 0.9581782790621028 0.929632212467086 0.9822198091669492 0.9753228737175983 0.9322681645369731 1.0 15.69239133382103 -4.76093352164241 5.85713776306551 0.9529388339057699 1.3459716512387245 0.9390905004483846 0.028623092700922212 0.02968596602706568 3.7055870950197547 0.007048557201121513 0.04699741542065798 1.7340694150435232e-05 4.76093352164241 0.3930328173329546 DMES(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 2 DMESPTK 7 0 E7EVA0;P27816;P27816-6;P27816-2;P27816-5;H7C456 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 DMES(0.99)PT(0.01)K;DMES(1)PTK 76.221 0.027802999999999998 20961700.0 131477.0 213720.0 178340.0 185821.0 234060.0 208550.0 244800.0 249910.0 174517.0 188475.0 True False 129602.11387007112 213225.14447091718 163677.57361230825 199486.89622068426 220293.050979665 199630.80265379458 257474.54618440042 261521.73094130956 154861.05771451915 221052.65262284863 0.5862952212167893 0.9645898474455927 0.7404460958519621 0.9024406350872476 0.9965637071793947 0.9030916403179148 1.1647656932834614 1.1830743844884217 0.700561861063649 1.0 17.75403052111453 -3.917687459546687 0.4938307180772158 1.0149256444691488 6.782121235225898e-13 0.3401494991240537 0.1487609005594689 11.85724576585127 1.1644732966271532 0.08833766131265398 8.37891750672467 0.0001208683352364399 3.917687459546687 -1.0149256444684707 DMES(ph)PTKLDVTLAK ddPTM_PC-9_AZD4547_30min_R2 4 DMESPTKLDVTLAK 14 1 E7EVA0;P27816;P27816-6;P27816-2;P27816-5;H7C456 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 DMES(0.858)PT(0.142)KLDVTLAK;DMES(0.978)PT(0.022)KLDVTLAK;DMES(0.957)PT(0.042)KLDVT(0.001)LAK;DMES(0.984)PT(0.015)KLDVT(0.001)LAK 128.85 5.299e-05 948576000.0 203735.0 204176.0 178791.0 247134.0 230058.0 210494.0 187799.0 201254.0 201438.0 210718.0 True False 268518.4920487444 270171.89912070415 176420.11452003583 190161.07448223812 198118.41779014046 197331.7769044814 204512.74718513063 170154.81865684353 212085.60143617252 203340.8269575671 1.3205340809633792 1.3286652914866097 0.867607932748552 0.9351839339274483 0.9743169670077301 0.970448383912889 1.0057633297016544 0.8367961378083272 1.0430055026796476 1.0 17.633540384335333 -5.2539720691722644 24.99317134288046 0.9507812600665044 1.3245997441018567 0.8622069037658777 0.059226942407206655 173.59044681263606 581005.5767446223 0.014463644605372689 0.0366887102764695 5.572215844312761e-06 5.2539720691722644 0.3738184840353522 DMES(ph)PTKLDVTLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DMESPTKLDVTLAK 14 1 E7EVA0;P27816;P27816-6;P27816-2;P27816-5;H7C456 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 DMES(0.94)PT(0.06)KLDVTLAK;DMES(0.999)PT(0.001)KLDVTLAK 175.26 0.00057233 148355000.0 70872.0 64631.0 56694.0 76646.0 70769.0 60580.0 86851.0 72554.0 52656.0 58223.0 True False 82869.22981419424 71047.13854860136 58045.79997319232 72351.77310968483 56902.32246951716 57403.07815500496 78623.84453321203 70649.53437731732 53425.994384635014 68778.3690069856 1.2048734363819749 1.0329866726177432 0.8439542956782938 1.0519553480882382 0.8273287559892235 0.8346094707359913 1.1431478482024844 1.0272057246681974 0.7767848402919922 1.0 16.06966728411097 -4.863070231410017 3.336167010319475 0.9423737141294782 1.2182874576164293 0.34530433068621014 0.11203607425663162 0.31915694548489765 5.923916248419036 0.028764081315645548 0.20135901669363387 1.3706600935924004e-05 4.863070231410017 0.2759137434869511 DMES(ph)PTKLDVTLAK ddPTM_PC-9_Lapatinib_30min_R1 8 DMESPTKLDVTLAK 14 1 E7EVA0;P27816;P27816-6;P27816-2;P27816-5;H7C456 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 DMES(0.942)PT(0.058)KLDVTLAK;DMES(0.788)PT(0.212)KLDVTLAK;DMES(0.956)PT(0.044)KLDVTLAK;DMES(0.838)PT(0.161)KLDVT(0.001)LAK;DMES(0.678)PT(0.307)KLDVT(0.014)LAK;DMES(0.98)PT(0.02)KLDVTLAK;DMES(0.976)PT(0.024)KLDVTLAK;DMES(0.859)PT(0.139)KLDVT(0.001)LAK 191.36 6.9580999999999995e-06 555973800.0 572851.0 501594.0 490100.0 467574.0 512474.0 485284.0 458003.0 476571.0 470255.0 427136.0 True False 564682.0396919914 500432.58991084463 449805.86984071037 501960.9517411404 482331.28688264964 464529.53457225696 481716.15431410953 498714.2284679707 417289.9298953174 500965.88847705675 1.1271866062749953 0.9989354593227229 0.8978772411194033 1.0019862894599643 0.9628026537873535 0.927267794588636 0.9615747606659074 0.9955053626187381 0.8329707460998683 1.0 18.934352845920316 -4.819534061980486 3.249952936148541 0.9494061870229911 1.1445974004610064 0.5434726184081637 0.04967072525320566 0.21726264656926897 3.681415418934052 0.011920044553675164 0.10257360878587378 1.5151859620813499e-05 4.819534061980486 0.19519121343801538 DMHDWLYAFNPLLAGT(ph)IR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DMHDWLYAFNPLLAGTIR 18 0 A0A3B3ITK3;A0A3F2YNW9;A0A3B3IUA1;A0A3B3IU40;A0A3B3IT28;A0A3B3ITE5;A0A3B3ITF7;A0A3B3ITW6;Q12756;Q12756-3;Q12756-2;H7C3Y8 A0A3B3ITK3 KIF1A Kinesin-like protein KIF1A 1 DMHDWLYAFNPLLAGT(1)IR 81.594 0.018393 0.0 14137.0 14680.0 19613.0 17532.0 17355.0 14975.0 14689.0 15369.0 15231.0 14367.0 True False 16530.114881522535 16137.333383259856 20080.64830271671 16549.738879510893 13954.412333909926 14189.684638019147 13297.551580849426 14965.580034801553 15453.724560778932 16971.623370890586 0.9739854886171162 0.9508420632841943 1.1831896020718127 0.9751417715229704 0.8222202454624509 0.8360829325471029 0.7835167732779847 0.8818001500357496 0.9105625444932318 1.0 14.050836947795956 -6.086468922015058 5.114684361487568 0.8614297691214051 1.0351442830600501 0.462718199189433 0.07961590843932069 0.18536188170143622 8.091762269539217 0.023851319963190985 0.031469867694213116 8.194662618460004e-07 6.086468922015058 0.173714513938645 DMHSAYK ddPTM_PC-9_AZD4547_30min_R2 2 DMHSAYK 7 0 P08621;P08621-2 P08621 SNRNP70 U1 small nuclear ribonucleoprotein 70 kDa 0 ; 81.78399999999999 0.015903 6695100.0 46439.0 35510.0 48985.0 65478.0 59412.0 47712.0 46294.0 46229.0 51599.0 58181.0 False True 61205.636008794034 46987.91306410253 48335.42689376957 50383.05872501559 51163.669325769355 44728.561097544996 50414.07631663867 39085.37028673828 54326.41779855367 56144.10089891817 1.0901525721996803 0.8369162977371312 0.8609172846278661 0.8973882904586047 0.9112919880556003 0.7966742788895006 0.8979407544063117 0.6961616565399733 0.9676246823573317 1.0 15.776846825132255 -4.757217039426464 24.984991521384572 0.864222491436491 1.0901529067084876 0.3805988718116299 0.08194128529926534 119.91558187102416 709486.5933270247 0.01891817580636879 0.14297374671462493 1.7489724181606343e-05 4.757217039426464 0.22593041527199664 DMHSAYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DMHSAYK 7 0 P08621;P08621-2 P08621 SNRNP70 U1 small nuclear ribonucleoprotein 70 kDa 0 ;;; 92.47 0.0098822 7526200.0 70605.0 78065.9 78312.0 86761.0 106883.0 92653.0 81682.0 85962.0 89786.0 73836.4 False True 82557.03198768478 85815.7666324406 80179.25507991368 81900.0624529571 85940.04341603548 87794.11357371531 73944.48963353137 83705.58858426778 91098.95039157601 87222.35483137908 0.9465123034947469 0.9838735356130004 0.9192512084192024 0.938980180153228 0.9852983628128064 1.006555185805767 0.847769929813098 0.959680448276018 1.0444449770668458 1.0 16.412410320412583 -8.174618282709666 6.127927424389446 1.021530035185769 0.9477297164008355 0.32626590104117625 0.042558537383175776 0.2586240251486977 14.472483854229981 0.030142613079229694 0.011052954647548302 6.689316076940267e-09 8.174618282709666 -0.07380031878493354 DMHSAYK ddPTM_PC-9_Lapatinib_30min_R1 1 DMHSAYK 7 0 P08621;P08621-2 P08621 SNRNP70 U1 small nuclear ribonucleoprotein 70 kDa 0 66.682 0.036391 3530000.0 10520.0 9415.1 11383.0 9607.9 10733.0 9279.6 9464.8 9599.3 11995.0 8016.2 False True 10369.982870868269 9393.299914412019 10447.133679650682 10314.497017014834 10101.706041889887 8882.73313980414 9954.841032377926 10045.318521967545 10643.996787050293 9401.789489084917 1.1029796915690768 0.9990970256584926 1.1111856622379566 1.0970780646588112 1.0744450355560018 0.9447917494979675 1.0588240721551019 1.068447504980806 1.1321245598412437 1.0 13.198719662869417 -3.3972702798670356 14.27658396279022 1.0589108229778894 1.0635943553282032 0.0 0.05647594137060974 0.0 0.0 0.012934837876449508 0.0 0.00040061731888882515 3.3972702798670356 0.004683532350313824 DMLPS(ph)PEQTLSPLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DMLPSPEQTLSPLSK 15 0 A0A0X1KG75;A0A590PXD8;A0A0D9SG04;Q53SF7;Q53SF7-3;Q53SF7-2 A0A0X1KG75 COBLL1 Cordon-bleu protein-like 1 1 DMLPS(0.998)PEQT(0.001)LS(0.001)PLSK 85.469 0.025663 0.0 8902.7 9653.2 8431.9 9262.9 11377.0 8197.1 9905.4 7101.7 10552.0 7043.6 True False 10409.751273659951 10611.50590022371 8632.948474158826 8743.929743726982 9147.758520477855 7767.229645830169 8967.088803114295 6915.28789987313 10706.30303757726 8320.548922893084 1.2510894858172945 1.2753372401942507 1.037545545872125 1.0508837607659527 1.099417671267913 0.9334996666457285 1.077703993596183 0.8311095774999254 1.2867303752183985 1.0 13.02246299358285 -5.264042598390598 23.251356093783052 1.0336887853429437 1.2632133977094697 0.3930394200702799 0.11095193614397843 71.85469103157281 641813.0290553138 0.02674470158556497 0.06021083474375309 5.4444924714620095e-06 5.264042598390598 0.229524612366526 DMLPSPEQTLS(ph)PLSK ddPTM_PC-9_AZD4547_30min_R2 1 DMLPSPEQTLSPLSK 15 0 A0A0X1KG75;A0A590PXD8;A0A0D9SG04;Q53SF7;Q53SF7-3;Q53SF7-2 A0A0X1KG75 COBLL1 Cordon-bleu protein-like 1 1 DMLPSPEQT(0.07)LS(0.898)PLS(0.031)K 88.311 0.0043046000000000004 2427900.0 13272.0 12092.0 14367.0 16373.0 15667.0 17998.0 14396.0 19523.0 14432.0 15967.0 True False 17492.219925250643 16000.502528052037 14176.48419276897 12598.457810328358 13491.907482105102 16872.582214822574 15677.216111252652 16506.168943909477 15194.846056488046 15408.00018997656 1.1352686727398889 1.0384542011143614 0.9200729502840522 0.8176569090727357 0.8756429981667613 1.0950533493502146 1.017472476502903 1.0712726337222733 0.986166009160152 1.0 13.911392005631507 -6.769221498231389 24.999489048037116 1.0374148965906018 0.9520817338296842 0.1618917374900175 0.08651457691871293 346.4425574613255 1112914.7125042314 0.03353687235282279 0.030121707381726436 1.701290597366119e-07 6.769221498231389 -0.08533316276091762 DMPGGFLFEGLS(ph)DDEDDFHPNTR ddPTM_PC-9_AZD4547_30min_R2 6 DMPGGFLFEGLSDDEDDFHPNTR 23 0 H3BUV9;Q96S82 H3BUV9 UBL7 Ubiquitin-like protein 7 1 DMPGGFLFEGLS(0.998)DDEDDFHPNT(0.002)R;DMPGGFLFEGLS(0.998)DDEDDFHPNT(0.002)R;DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(1)DDEDDFHPNTR 138.59 4.8436000000000004e-08 29770500.0 25312.73 25642.45 33913.770000000004 48020.740000000005 41622.25 32561.93 30397.66 37774.9 32625.420000000002 34518.61 True False 33361.65160250825 33930.870497059856 33464.051250936325 36950.300306037214 35843.7190398321 30525.82736961314 33102.99285192973 31937.657185846747 34349.933095085 33310.12397054715 1.0015469060399373 1.0186353712481397 1.00462103595067 1.109281380600946 1.0760608117677724 0.9164129018734397 0.9937817367836708 0.9587973078120651 1.031216008846357 1.0 15.023673102861046 -6.744997832157487 24.999427051405075 0.9783251629604152 1.042387457263715 0.36084617006329234 0.041216177667496946 280.8285604051 427000.0055975119 0.01420797764841321 0.014169022658619645 1.7988798944705508e-07 6.744997832157487 0.0640622943032999 DMPGGFLFEGLS(ph)DDEDDFHPNTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 11 DMPGGFLFEGLSDDEDDFHPNTR 23 0 H3BUV9;Q96S82 H3BUV9 UBL7 Ubiquitin-like protein 7 1 DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(0.999)DDEDDFHPNT(0.001)R;DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(0.999)DDEDDFHPNT(0.001)R;DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(1)DDEDDFHPNTR 130.48 9.5763e-08 32374400.0 50847.2 54281.5 60867.100000000006 67848.20000000001 69543.70000000001 59861.94 59446.86 59950.37 58413.33 51183.59 True False 59454.62668202251 59670.208586064015 62318.40250376221 64046.88532083223 55917.111208627546 56722.67448547734 53815.623062804414 58376.73631016756 59267.51444408674 60462.76969792449 0.9833262184160811 0.9868917498186048 1.0306905028517312 1.0592780588916815 0.9248188842157361 0.9381421785483385 0.8900621544740738 0.9654988781000462 0.9802315497650982 1.0 15.883759447465415 -6.274787503301107 24.922611413668378 0.9444982057227558 1.0141529903436675 0.45179147860451907 0.03491781301895327 686.5350693608776 1281843.75109781 0.011314208929798132 0.012896306656323265 5.311442651586952e-07 6.274787503301107 0.06965478462091168 DMPGGFLFEGLS(ph)DDEDDFHPNTR ddPTM_PC-9_Lapatinib_30min_R1 11 DMPGGFLFEGLSDDEDDFHPNTR 23 0 H3BUV9;Q96S82 H3BUV9 UBL7 Ubiquitin-like protein 7 1 DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(0.989)DDEDDFHPNT(0.011)R;DMPGGFLFEGLS(0.992)DDEDDFHPNT(0.008)R;DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(0.998)DDEDDFHPNT(0.002)R;DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(0.997)DDEDDFHPNT(0.003)R;DMPGGFLFEGLS(0.999)DDEDDFHPNT(0.001)R 124.73 1.5804e-08 17429410.0 69714.0 62322.0 74519.9 58390.700000000004 61887.02 63168.5 57215.95 57422.38 75428.8 44219.840000000004 True False 68719.86557601814 62177.69723805228 68393.16147713277 62684.946863665115 58246.94715816271 60466.930507965604 60178.311931206554 60090.43340550441 66933.21424352305 51863.18042476695 1.3250222029037269 1.1988793731662413 1.318722857275294 1.2086599076698794 1.1230886089343497 1.1658932216021598 1.1603282220322293 1.1586337920920982 1.2905728822515383 1.0 15.66242305936867 -14.522878745278893 0.05819241737614142 0.33105608115183044 1.5111529872627962 0.4986380954779771 0.06646692145387281 387.99939746172333 1.6470457258615352 38.841442936552745 6.794794707607124 3.0000000000099774e-15 14.522878745278893 1.1800969061109658 DMPHPLAGSSSEEAVGGDSTPS(ph)PDLLMAR ddPTM_PC-9_AZD4547_30min_R2 1 DMPHPLAGSSSEEAVGGDSTPSPDLLMAR 29 0 Q5VWJ9 Q5VWJ9 SNX30 Sorting nexin-30 1 DMPHPLAGSSSEEAVGGDS(0.065)T(0.065)PS(0.87)PDLLMAR 80.632 1.0869e-06 6129900.0 8448.5 6606.8 14045.0 21601.0 17785.0 16491.0 13771.0 15663.0 8515.6 12103.0 True False 11134.947260283298 8742.318896984303 13858.754123160028 16621.22318212318 15315.859741446313 15459.815163053621 14996.592322038096 13242.64324993363 8965.71723105804 11679.277653866486 0.9533934880464988 0.7485324997038763 1.1866105536562885 1.4231379435200462 1.311370462742267 1.3236961755023924 1.2840342328083445 1.133858072596603 0.7676602523521558 1.0 13.51166342796165 -5.275850728571006 21.54775222663925 1.2059715702710516 0.8509631212302123 0.32857029294159135 0.18420731704032453 121.67247722151241 181925.80480858832 0.05032771870352366 0.1059450490902436 5.298455258924482e-06 5.275850728571006 -0.3550084490408393 DMQGLS(ph)LDAASQPSK ddPTM_PC-9_AZD4547_30min_R2 1 DMQGLSLDAASQPSK 15 0 E9PLZ8;Q96EY5;E9PLL0;M0QZK6;E9PQA6;Q96EY5-3 E9PLZ8 MVB12A Multivesicular body subunit 12A 1 DMQGLS(0.996)LDAAS(0.004)QPSK 96.561 0.0023076 17415000.0 53133.0 50997.0 75992.0 69191.0 148940.0 92919.0 71034.0 84725.0 73814.0 67048.0 True False 70028.18876494438 67480.78294931115 74984.29642770918 53240.08394029373 128262.2518915384 87108.76024108769 77355.88838890813 71632.69803681441 77715.65734573234 64700.6699278229 1.0823410150631303 1.042968844443027 1.1589415768238291 0.8228675839011547 1.9823944950588903 1.346334749520557 1.1955964053417503 1.1071399742340313 1.2011569189689746 1.0 15.981493029890016 DMQGLS(ph)LDAASQPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DMQGLSLDAASQPSK 15 0 E9PLZ8;Q96EY5;E9PLL0;M0QZK6;E9PQA6;Q96EY5-3 E9PLZ8 MVB12A Multivesicular body subunit 12A 1 DMQGLS(1)LDAASQPSK;DMQGLS(0.985)LDAAS(0.015)QPSK;DMQGLS(1)LDAASQPSK 118.23 0.00010224 37475000.0 217909.0 183821.0 216557.0 251835.0 287990.0 272987.0 184885.0 254814.0 189459.0 143827.0 True False 254796.68980106726 202069.53404933345 221720.54017699574 237725.5014100864 231560.4268535129 258671.0811538518 167371.35434851548 248125.4024977499 192229.4794537864 169901.69656609447 1.4996712507926446 1.189332055732152 1.3049930910533487 1.3991943942573133 1.3629082671545438 1.5224749745404962 0.9851070220679365 1.4604056787698123 1.1314158913004502 1.0 17.374340733170072 -8.714412891424205 0.6621948692888049 0.9944395470130817 1.3524151375714712 0.3392512299208724 0.1535116264392684 1.2118289509155862 1.1338336487307685 0.15385380329035672 0.05931447344115178 1.9301324335028093e-09 8.714412891424205 0.35797559055838957 DMQGLS(ph)LDAASQPSK ddPTM_PC-9_Lapatinib_30min_R1 3 DMQGLSLDAASQPSK 15 0 E9PLZ8;Q96EY5;E9PLL0;M0QZK6;E9PQA6;Q96EY5-3 E9PLZ8 MVB12A Multivesicular body subunit 12A 1 DMQGLS(1)LDAASQPSK;DMQGLS(1)LDAASQPSK;DMQGLS(0.988)LDAAS(0.012)QPSK 113.33 0.00019865 34192600.0 202614.0 163276.0 324068.0 337973.0 238173.0 175432.0 155892.0 159938.0 270736.0 197779.0 True False 199724.68720514257 162897.94445364742 297424.379978655 362828.66186487774 224164.13240613427 167929.18231196608 163963.32497458585 167369.30336237483 240242.86070353066 231964.83662604756 0.8610127729278226 0.7022527501280573 1.2821959754966454 1.5641537189095467 0.9663711779191393 0.7239424076274376 0.7068456036675614 0.7215287704670181 1.0356865471417471 1.0 17.82354659931513 -6.5238412908528725 24.757269025188744 0.815705376449551 1.1089886804271485 0.21038648153967188 0.23991633884393326 46.42488174562807 1194018.1920144868 0.08652801932982347 0.08725216872356614 2.993358333564558e-07 6.5238412908528725 0.2932833039775975 DMQPLS(ph)PISVHER ddPTM_PC-9_AZD4547_30min_R2 6 DMQPLSPISVHER 13 0 P28749;P28749-2 P28749 RBL1 Retinoblastoma-like protein 1 1 DMQPLS(1)PISVHER;DMQPLS(1)PISVHER;DMQPLS(0.998)PIS(0.002)VHER;DMQPLS(0.999)PIS(0.001)VHER;DMQPLS(1)PISVHER;DMQPLS(1)PISVHER 108.97 0.00047515 61086500.0 70095.1 59739.5 243120.0 412790.0 265112.0 236752.0 154292.0 309165.0 169481.0 243046.0 True False 92383.88373134709 79049.12510540563 239896.06994821402 317627.643041925 228305.77496622494 221947.8600135386 168023.68909679027 261390.65315493385 178439.41965768085 234537.03351744535 0.39389891799102755 0.33704325461900153 1.0228494253141904 1.3542750084212145 0.9734316646809771 0.9463233020597988 0.7164057913450684 1.1144962875787847 0.7608155393694283 1.0 17.839456217448607 -5.261294586528064 24.9998286858061 0.9918115512325925 0.3654710304377647 0.6869602201881972 0.16753880108069324 6.925804496552785 1195523.9521707792 0.04526086776909382 0.10537692426659007 5.479051889762856e-06 5.261294586528064 -0.6263405207948278 DMQPLS(ph)PISVHER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DMQPLSPISVHER 13 0 P28749;P28749-2 P28749 RBL1 Retinoblastoma-like protein 1 1 DMQPLS(1)PISVHER;DMQPLS(1)PISVHER;DMQPLS(0.999)PIS(0.001)VHER 84.94 0.0057817 31529900.0 52219.0 67954.0 161435.0 175892.0 204037.0 190831.0 165034.0 156693.0 162100.0 107612.0 True False 61058.64532773752 74700.02402765953 165284.2226456465 166037.3414895578 164057.41454185976 180823.48642122422 149400.7847773098 152579.97477995683 164470.40583692896 127121.20374387677 0.48031833816456143 0.5876283564633702 1.3002097036357556 1.3061341192464562 1.2905590075468598 1.4224494505696041 1.1752625083563701 1.2002716327905003 1.2938078069831938 1.0 16.955845165556674 -5.233098961454904 5.412642370118752 1.263844957392216 0.5186155159720273 0.8760239058511997 0.1075124423221825 0.0529965196021927 4.690820160505127 0.026736614194109685 0.07012086407950104 5.84656844863475e-06 5.233098961454904 -0.7452294414201887 DMQPLS(ph)PISVHER ddPTM_PC-9_Lapatinib_30min_R1 2 DMQPLSPISVHER 13 0 P28749;P28749-2 P28749 RBL1 Retinoblastoma-like protein 1 1 DMQPLS(1)PISVHER;DMQPLS(1)PISVHER 110.26 0.00039447 9802100.0 46831.0 29459.0 85945.0 35301.0 62300.0 86177.0 46814.0 45683.0 82144.0 42714.0 True False 46163.18135224639 29390.789495455578 78878.93385729397 37897.153300683865 58635.63648651259 82491.41059839884 49237.79985733881 47805.598953990775 72892.07770533225 50097.057987172586 0.921474897070134 0.5866769562192878 1.5745222778848815 0.7564746279190183 1.1704407173276785 1.6466318365346098 0.982848131919168 0.9542596087425226 1.4550171334212152 1.0 15.612438261374253 -5.241309490001551 24.96329851242405 1.1832585237217321 0.7540759149843644 0.27571205195134363 0.283936119033187 1055.7643528529807 1309260.5100445992 0.0703648859197837 0.185645034395976 5.737074770227338e-06 5.241309490001551 -0.4291826087373677 DMS(ph)PLSETEMALGK ddPTM_PC-9_AZD4547_30min_R2 5 DMSPLSETEMALGK 14 0 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 DMS(0.997)PLS(0.002)ET(0.001)EMALGK;DMS(0.992)PLS(0.004)ET(0.004)EMALGK;DMS(0.99)PLS(0.01)ET(0.001)EMALGK;DMS(0.991)PLS(0.007)ET(0.002)EMALGK;DMS(0.901)PLS(0.062)ET(0.037)EMALGK 93.348 0.0022649000000000002 98810300.0 324773.0 385580.0 389625.0 372674.0 396368.0 454532.0 400319.0 446056.0 477710.0 413239.0 True False 428044.05830194504 510211.19457213883 384458.31792354747 286759.76705590344 341339.1450097035 426110.04218622757 435946.6154793373 377128.2945471742 502960.7753357065 398771.62839016254 1.0734065009337677 1.2794571084002562 0.96410649743464 0.7191077464902657 0.8559765056197367 1.0685565668411015 1.093223751246421 0.9457249906911324 1.2612752250358297 1.0 18.605203243659204 -9.333462424509326 13.698608354121088 1.0001201287190702 1.0208428777883334 0.0006093152808730462 0.16188091107408661 0.0 0.0 0.16836960314230134 0.040835626935237394 4.640209356915687e-10 9.333462424509326 0.02072274906926319 DMS(ph)PLSETEMALGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DMSPLSETEMALGK 14 0 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 DMS(0.898)PLS(0.048)ET(0.053)EMALGK;DMS(0.98)PLS(0.019)ET(0.001)EMALGK 89.74700000000001 0.0031099 14373000.0 57388.0 77352.0 61017.0 67254.0 73145.0 47722.2 65021.0 48268.0 47428.1 41415.5 True False 67102.654935334 85030.99535844116 62471.876688261145 63485.97642040993 58812.76232577599 45219.56382186824 58861.740168725555 47001.01614417339 48121.64623735012 48923.80230508239 1.3715748117223325 1.7380291668296561 1.276921942793709 1.2976500891022276 1.2021298336345028 0.924285556136561 1.2031309382224933 0.9606983498764311 0.9836039712790487 1.0 15.578248912472693 -5.960984140717343 0.953181408560874 1.0134775991576894 1.5641018874462451 0.7108750070492076 0.12659632898274828 0.318895729620887 0.5809507841031193 0.052354582693403866 0.12162683839624207 1.093996315386646e-06 5.960984140717343 0.5506242882885557 DMS(ph)PLSETEMALGK ddPTM_PC-9_Lapatinib_30min_R1 8 DMSPLSETEMALGK 14 0 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 DMS(0.972)PLS(0.018)ET(0.01)EMALGK;DMS(0.966)PLS(0.007)ET(0.027)EMALGK;DMS(0.993)PLS(0.006)ET(0.002)EMALGK;DMS(0.926)PLS(0.059)ET(0.015)EMALGK;DMS(0.827)PLS(0.116)ET(0.057)EMALGK;DMS(0.922)PLS(0.042)ET(0.036)EMALGK;DMS(1)PLSETEMALGK;DMS(1)PLSETEMALGK 222.56 8.8225e-17 36354300.0 165443.8 269728.0 252120.0 228602.0 305155.0 292535.0 284672.0 280572.0 269026.0 260756.0 True False 163084.54107332326 269103.4613880386 231391.66681134398 245414.15367391618 287206.38285781327 280023.9599823919 299410.9232492066 293608.3993984437 238725.45891062892 305827.32716446987 0.5332569282980345 0.8799196065409758 0.7566088647366186 0.8024598584741112 0.9391128828175563 0.9156276601528115 0.9790195206728123 0.9600463180340487 0.7805890373630527 1.0 18.222357798739232 -4.0478256627833975 0.6173921783083985 0.926914230628164 1.0980684799699195e-15 0.6154720807088621 0.08326671523173992 5.649586925881457 0.8377893967739535 0.03807572306217529 4.551077818604628 8.957242606437432e-05 4.0478256627833975 -0.9269142306281629 DMS(ph)PPFICEETDEQK ddPTM_PC-9_AZD4547_30min_R2 1 DMSPPFICEETDEQK 15 0 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 DMS(1)PPFICEETDEQK 89.992 0.019853 0.0 9254.8 11729.0 11296.0 8894.0 9382.3 11340.0 13731.0 12732.0 13502.0 10918.0 True False 12197.633888201442 15520.169876903927 11146.207659324718 6843.625710930218 8079.729595286576 10630.908007339038 14953.032399528354 10764.56195225404 14215.688155120673 10535.76414318056 1.157736042914035 1.4730938986470765 1.0579401273460811 0.6495614003811828 0.7668859596212875 1.0090305613209898 1.419264155529425 1.0217162994505313 1.3492792702959284 1.0 13.363007334008183 -5.372815569731232 7.171554517724467 1.022807859169899 1.3134254544392012 0.19566500538122078 0.2278985912749462 0.4067126746999566 22.981758244571264 0.06514581139784101 0.1366482046058169 4.2382291118317e-06 5.372815569731232 0.2906175952693022 DMS(ph)PPFICEETDEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DMSPPFICEETDEQK 15 0 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 DMS(1)PPFICEETDEQK 121.42 0.0011296 0.0 9881.6 12859.0 9219.2 10761.0 10888.0 7061.2 8400.5 6473.9 10368.0 7723.9 True False 11554.359709503648 14135.556537829601 9439.020692010701 10158.096057632718 8754.574560161978 6690.8982414678285 7604.743825646779 6303.966984664044 10519.612385671064 9124.181927641246 1.2663447310821698 1.549240978526157 1.0345059718083511 1.1133158170442965 0.959491451353073 0.7333148653248673 0.833471305806452 0.6909076380389233 1.1529375969370395 1.0 13.155479497586704 -5.6662437663602 1.235696426103005 0.8672797716357974 1.4195475951003513 0.5809733813390909 0.1578901777340866 0.3368188922078994 0.9814479222316003 0.052873137858989304 0.1584136708168849 2.156533622613917e-06 5.6662437663602 0.5522678234645539 DMSPLSET(ph)EMALGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DMSPLSETEMALGK 14 0 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 DMS(0.281)PLS(0.015)ET(0.704)EMALGK 71.933 0.021266999999999998 13359000.0 43735.0 59296.0 44097.0 54769.0 50049.0 43137.0 46641.0 35577.0 36532.0 33689.0 True False 51138.47169437559 65182.51500638806 45148.4397188038 51700.47049349374 40242.25772975267 40874.81978165155 42222.82682840205 34643.14144694742 37066.211388246105 39796.54901802274 1.2849976431679142 1.637893651956322 1.134481276212099 1.2991194404841497 1.0111996824530711 1.02709457956117 1.0609670403652467 0.8705061695489855 0.9313926031993341 1.0 15.280355711563482 -5.94628331983106 0.8606947565113271 0.9511391967279621 1.4713146540021413 0.6845379998128143 0.12092958043312751 0.37931737036204144 0.5542406445470544 0.0532955606585597 0.13415349184819858 1.131661862366624e-06 5.94628331983106 0.5201754572741792 DMSPLSETEMALGKDVT(ph)PPPETEVVLIK ddPTM_PC-9_AZD4547_30min_R2 4 DMSPLSETEMALGKDVTPPPETEVVLIK 28 1 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 DMS(0.008)PLS(0.143)ET(0.143)EMALGKDVT(0.703)PPPET(0.003)EVVLIK;DMS(0.011)PLS(0.148)ET(0.148)EMALGKDVT(0.681)PPPET(0.012)EVVLIK;DMS(0.019)PLS(0.06)ET(0.056)EMALGKDVT(0.86)PPPET(0.005)EVVLIK;DMSPLSET(0.007)EMALGKDVT(0.991)PPPET(0.002)EVVLIK 71.905 3.0981e-05 62166300.0 129676.0 111455.0 147452.0 194840.0 182629.0 174481.0 124516.0 166236.0 142343.0 168129.0 True False 170910.27057163994 147480.64912868344 145496.69013657473 149922.64824799245 157274.11575600805 163570.67548752387 135597.68278054567 140548.04592325623 149866.9603810059 162242.85488448455 1.053422480104449 0.9090116740961464 0.8967833451905606 0.9240631789593201 0.9693746813564504 1.0081841545748484 0.8357698271340824 0.8662818835586021 0.9237199412430817 1.0 17.307795418302504 -7.258420075764679 24.988915927682218 0.8952997386107708 0.9537159714673641 0.14844254386565137 0.059521555027761484 478.45001928380805 3959857.4669548045 0.02354133651082091 0.017457126752110575 5.51543694926361e-08 7.258420075764679 0.05841623285659325 DMSPLSETEMALGKDVT(ph)PPPETEVVLIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DMSPLSETEMALGKDVTPPPETEVVLIK 28 1 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 DMS(0.004)PLS(0.011)ET(0.038)EMALGKDVT(0.931)PPPET(0.016)EVVLIK;DMS(0.004)PLS(0.089)ET(0.089)EMALGKDVT(0.814)PPPET(0.004)EVVLIK;DMSPLSETEMALGKDVT(0.986)PPPET(0.013)EVVLIK 56.468 0.00089225 51220900.0 117003.0 95954.1 111410.0 151386.0 164355.0 158130.0 151096.0 158683.0 135328.0 124724.0 True False 136809.29698541266 105479.78890944521 114066.43692477772 142904.3332200342 132150.8175822391 149837.3844280444 136783.09303969098 154517.73938853657 137306.9159845773 147335.4738853591 0.9285563983855185 0.7159157677907118 0.7741953374618538 0.9699248215757412 0.8969382192713814 1.01698104656474 0.9283785461342537 1.04874770015513 0.9319338538349226 1.0 17.16874530356783 -5.766030143719496 24.999369455070166 0.9695732745634404 0.7971918116588766 0.5717215741331919 0.06497912986918447 73.29311096113867 399126.38349275937 0.01745280614407687 0.026890074516267053 1.7138383484668003e-06 5.766030143719496 -0.1723814629045638 DMSPLSETEMALGKDVT(ph)PPPETEVVLIK ddPTM_PC-9_Lapatinib_30min_R1 2 DMSPLSETEMALGKDVTPPPETEVVLIK 28 1 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 DMS(0.001)PLS(0.023)ET(0.021)EMALGKDVT(0.955)PPPET(0.001)EVVLIK;DMS(0.017)PLS(0.016)ET(0.015)EMALGKDVT(0.952)PPPET(0.001)EVVLIK 65.428 9.4257e-05 11622000.0 119290.0 81505.3 89351.1 84266.0 82406.3 82847.1 69408.0 74438.0 81266.7 64288.9 True False 117588.90272489292 81316.57948552053 82004.99746322041 90463.20274313538 77559.3234510193 79303.92265902279 73001.60662404778 77896.66122927918 72113.58846971074 75401.15070542539 1.559510718666419 1.078452765306001 1.087582837874646 1.199758914775106 1.0286225438922727 1.0517601113124204 0.9681762936118566 1.0330964514534158 0.956399044245911 1.0 16.20229892034237 -2.5112302478054183 1.283420432943966 1.03627153503289 199.99773936689004 0.8398191968726665 0.06714770311408362 220.01904043407754 1.2658816372895623 0.020621823891996315 127917.33500334095 0.0030815537846297972 2.5112302478054183 198.96146783185716 DNAMLEYLK ddPTM_PC-9_Lapatinib_30min_R1 1 DNAMLEYLK 9 0 P15311;E7EQR4 P15311 EZR Ezrin 0 96.89 0.022851 2941500.0 23889.0 21656.0 27439.0 23508.0 26981.0 23377.0 20349.0 20594.0 22844.0 23977.0 False True 23548.338479293947 21605.856862540673 25183.071337603018 25236.856740389136 25394.03062668694 22377.220204448615 21402.57165157832 21550.87242209325 20271.068162015585 28121.392502655734 0.8373816651174043 0.7683067920800954 0.8955129563809748 0.8974255715824105 0.9030146933260426 0.795736562559459 0.7610779462488246 0.7663515389594603 0.7208415500797559 1.0 14.77938041446259 -6.857835888698902 8.656583687087558 0.7907206578163017 0.8591424359504665 0.07304835209112936 0.079749834353941 0.5320572909455943 42.8132331561199 0.027469368415589824 0.024238698259323607 1.3872799555133973e-07 6.857835888698902 0.06842177813416472 DNDFIYHDR ddPTM_PC-9_AZD4547_30min_R2 1 DNDFIYHDR 9 0 Q8WUM4;Q8WUM4-2 Q8WUM4 PDCD6IP Programmed cell death 6-interacting protein 0 128.51 0.0011143 14041000.0 151760.0 156570.0 189480.0 258920.0 233530.0 196520.0 176890.0 234590.0 181990.0 218640.0 False True 200016.5231959039 207178.19060677363 186967.37139596755 199229.99427412325 201108.39052122363 184231.57333353284 192632.86731866412 198339.50584191555 191609.61986005132 210985.48014883712 0.9480108444183206 0.9819547319589117 0.8861622670151221 0.9442829626644398 0.9531859271991332 0.8731955071200584 0.9130148064348961 0.9400623479018527 0.9081649586733772 1.0 17.686784191672338 DNDFIYHDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DNDFIYHDR 9 0 Q8WUM4;Q8WUM4-2 Q8WUM4 PDCD6IP Programmed cell death 6-interacting protein 0 ; 117.52 0.0015553 23673200.0 223710.0 227810.0 236100.0 245790.0 281420.0 246200.0 258260.0 216880.0 216280.0 193501.0 False True 261579.6845260955 250425.47125616038 241729.51941423604 232019.18316193135 226277.77119037326 233288.83858967043 233795.74315951896 211187.1298033552 219442.68583843936 228581.19954692628 1.1443622005859446 1.0955646035305262 1.057521440491918 1.0150405353625738 0.989922931714775 1.0205950404148514 1.0228126531093917 0.923904197816583 0.9600207115607037 1.0 17.80234722341435 -3.8970316958237796 0.42450273247148307 0.9689596178153853 1.4692459640236588 0.8141839900608855 0.02610153193386635 4.721188037656767 0.3738094519750494 0.020110414693046454 1.3917594905952442 0.00012675593530452826 3.8970316958237796 0.5002863462082735 DNDFIYHDR ddPTM_PC-9_Lapatinib_30min_R1 2 DNDFIYHDR 9 0 Q8WUM4;Q8WUM4-2 Q8WUM4 PDCD6IP Programmed cell death 6-interacting protein 0 ; 113.69 0.0017495999999999998 28138000.0 211450.0 267750.0 272650.0 268670.0 290350.0 273000.0 264360.0 254350.0 302040.0 232000.0 False True 208434.6842248189 267130.0413255105 250233.76945943644 288428.88805684645 273272.18385006295 261324.4263940826 278047.2672765855 266168.02955032623 268021.0745777967 272100.8908794318 0.7660198522362668 0.9817315939765743 0.9196359800612167 1.0600071433968572 1.00430462747419 0.9603953355297016 1.021853571952429 0.9781960973742845 0.9850062368834989 1.0 18.053782154527653 -4.17760262156727 1.527873134586651 0.9949192121824181 7.609962373814348e-19 0.7769079149434116 0.03581010344740245 2.718402041586356 1.600846848596601 0.009669452159172094 6.439451532847189 6.643506716896543e-05 4.17760262156727 -0.9949192121824181 DNEESEQPPVPGT(ph)PTLR ddPTM_PC-9_AZD4547_30min_R2 2 DNEESEQPPVPGTPTLR 17 0 A0A2R8YDC1;A0A2R8Y6V8;O15439-4;O15439-3;O15439-2;O15439 A0A2R8YDC1 ABCC4 Multidrug resistance-associated protein 4 1 DNEESEQPPVPGT(0.876)PT(0.124)LR;DNEESEQPPVPGT(1)PTLR 287.75 1.3009999999999995e-96 15572100.0 36509.0 57979.0 61375.0 57433.0 55875.0 44414.0 61104.0 60207.0 47174.0 44330.0 True False 48118.10256562503 76719.57790885936 60561.12739828737 44192.70918100459 48117.72072270524 41636.78555890263 66542.13762586711 50903.39156922391 49667.52133237024 42778.02019300188 1.1248323870186199 1.7934345152656228 1.4157066438571333 1.0330704642622555 1.124823460871078 0.9733219389548573 1.5555216750482723 1.1899426700806335 1.161052360728359 1.0 15.384582094314393 -5.621356984503184 6.2037595888648775 1.1660509922257232 1.4935389469104774 0.28064380632312635 0.2151426003617873 0.24727528680145489 13.08330412458165 0.05763399954166049 0.10083979740359006 2.3913492898148256e-06 5.621356984503184 0.3274879546847542 DNEESEQPPVPGT(ph)PTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DNEESEQPPVPGTPTLR 17 0 A0A2R8YDC1;A0A2R8Y6V8;O15439-4;O15439-3;O15439-2;O15439 A0A2R8YDC1 ABCC4 Multidrug resistance-associated protein 4 1 DNEESEQPPVPGT(0.965)PT(0.035)LR;DNEESEQPPVPGT(0.993)PT(0.007)LR;DNEESEQPPVPGT(0.999)PT(0.001)LR;DNEESEQPPVPGT(0.673)PT(0.327)LR 164.69 6.8599e-05 24804300.0 42518.6 51063.1 51563.0 49325.1 116276.0 45496.399999999994 54352.8 62667.9 54339.6 49177.3 True False 49716.15919937073 56132.30710372866 52792.45747376648 46561.57456113182 93492.55249424985 43110.48869216519 49204.10930380505 61022.9340271286 55134.21384957671 58092.75520270739 0.8558065291600032 0.9662531396189078 0.9087614675798009 0.801503980981123 1.6093668163615118 0.7420975049597243 0.8469921788373349 1.0504396600608237 0.9490721116117281 1.0 15.82607063466221 DNEESEQPPVPGT(ph)PTLR ddPTM_PC-9_Lapatinib_30min_R1 5 DNEESEQPPVPGTPTLR 17 0 A0A2R8YDC1;A0A2R8Y6V8;O15439-4;O15439-3;O15439-2;O15439 A0A2R8YDC1 ABCC4 Multidrug resistance-associated protein 4 1 DNEESEQPPVPGT(0.999)PT(0.001)LR;DNEESEQPPVPGT(0.943)PT(0.057)LR;DNEESEQPPVPGT(0.97)PT(0.03)LR;DNEESEQPPVPGT(0.931)PT(0.069)LR;DNEES(0.001)EQPPVPGT(0.978)PT(0.021)LR 277.64 2.0972e-82 26650300.0 113208.0 130096.0 59208.9 44551.3 68672.0 52063.7 44081.3 40980.700000000004 78325.6 39481.8 True False 111593.63316019515 129794.77070507451 54340.97279496348 47827.7512207801 64632.84797434663 49837.056917412425 46363.61402254258 42884.81292940063 69503.74612286681 46306.17652380841 2.4099081707343957 2.8029688574771505 1.1735145692070683 1.0328590009194425 1.3957716405524332 1.0762507436084385 1.001240385258425 0.9261143145202524 1.5009605918798181 1.0 15.498917018951984 -5.267076290421763 24.915666994617645 1.1340131576883663 2.606438565177561 0.9020707184752985 0.1934826709371666 100.96123368561973 446259.89284350845 0.04868798135028682 0.1060699381178616 5.406593395787177e-06 5.267076290421763 1.4724254074891947 DNFTLIPEGTNGTEER ddPTM_PC-9_Lapatinib_30min_R1 2 DNFTLIPEGTNGTEER 16 0 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 0 ; 241.76 3.2039999999999995e-37 6469400.0 48705.0 49654.0 50404.0 46465.0 47337.0 48734.0 48640.0 41573.0 49011.0 46246.0 False True 48010.45776859689 49539.02921373269 46259.97768506659 49882.19110269613 44552.730728122755 46649.76042450265 51158.34120265214 43504.633349698066 43490.8650712899 54239.55948107845 0.885155746615999 0.9133376024378378 0.852882621607656 0.9196643848130368 0.821406573990798 0.8600689399178562 0.9431924169756356 0.8020830878037407 0.8018292458009685 1.0 15.727057840895307 -6.239628813464109 24.85830127110748 0.8645542516704738 0.8913815134683599 0.021152564135390906 0.06086981350279548 2913.4484066456166 3320563.499292408 0.017561487157134483 0.022645752181516064 5.759319695197202e-07 6.239628813464109 0.02682726179788608 DNFWEMGDTGPCGPCSEIHYDR ddPTM_PC-9_AZD4547_30min_R2 1 DNFWEMGDTGPCGPCSEIHYDR 22 0 P49588-2;P49588 P49588-2 AARS Alanine--tRNA ligase, cytoplasmic 0 82.56 0.00023024 3367400.0 9576.9 7538.4 9035.3 16848.0 13125.0 15789.0 11740.0 11320.0 10478.0 11033.0 False True 12622.154988105243 9975.040378553373 8915.486018439859 12963.953899005202 11302.820303991166 14801.71133402787 12784.837256606423 9570.754107721932 11031.845688739044 10646.73802818384 1.1855419899214312 0.9369104745648515 0.8373913206879849 1.217645617341882 1.061622843923703 1.39025787004856 1.2008220003875973 0.8989376917499441 1.036171422602468 1.0 13.378123861511243 -4.38748737394578 19.144951301436578 1.0726000598942544 45.335632417503675 0.048170819707835766 0.15779648614803263 777448.9363182803 5425787.047977612 0.04224702676303727 1438457589.5129504 4.0974402194977834e-05 4.38748737394578 44.26303235760942 DNGNGTYSCSYVPR ddPTM_PC-9_AZD4547_30min_R2 1 DNGNGTYSCSYVPR 14 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 141.34 2.1393000000000003e-05 0.0 4449.5 3998.3 4246.2 7031.3 6038.8 6204.8 2802.3 4229.9 6189.0 6078.6 False True 5864.348444650599 5290.672283982011 4189.892613582208 5410.342417502094 5200.416857275567 5816.812875126744 3051.699271225569 3576.266148432245 6516.137904906079 5865.790064181846 0.9997542326753135 0.9019539100603575 0.7142929712344912 0.9223552766641202 0.8865671632250813 0.99165036789261 0.5202537489127165 0.6096819199633355 1.1108713120667988 1.0 12.518109722824192 DNGNGTYSCSYVPR ddPTM_PC-9_Lapatinib_30min_R1 2 DNGNGTYSCSYVPR 14 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 257.02 3.5692e-44 15663600.0 12770.599999999999 12916.0 9592.0 9681.6 13587.8 11050.400000000001 14484.9 10398.2 11018.7 9155.8 False True 12588.488902158782 12886.09379555667 8803.38278619075 10393.617160870821 12788.592318642632 10577.800151740554 15234.857246839982 10881.338332495392 9777.657973945072 10738.367830663366 1.1722907150016226 1.2000048795833274 0.8198064105284907 0.9678954311093617 1.1909251499212812 0.9850472919670052 1.4187311784326206 1.013313988129907 0.9105348343558328 1.0 13.390487108296346 -7.991932636623 24.99736812543764 0.9574862983584916 1.1021366763562463 0.14159128751300798 0.15429456108004813 366.65580523353424 1136112.9047417878 0.08758610141217134 0.041961193464136654 1.0187493939241173e-08 7.991932636623 0.1446503779977547 DNGSYFFRMERGSTKYSYK ddPTM_PC-9_AZD4547_30min_R2 1 DNGSYFFRMERGSTKYSYK 19 3 P20138-2;P20138 P20138-2 CD33 Myeloid cell surface antigen CD33 0 49.049 0.043949 0.0 714.59 2135.9 2427.8 3218.8 3151.7 2334.9 2012.5 2662.8 2076.5 2810.6 False True 941.8147556046454 2826.2879051990035 2395.6057857036603 2476.7553899642658 2714.140857302016 2188.898333892057 2191.6086012709056 2251.325445056712 2186.25955074123 2712.2017494800607 0.34725099479977656 1.0420640373603525 0.8832697590298756 0.9131899536747475 1.0007149570721745 0.8070558668106741 0.8080551536002236 0.8300730008334739 0.8060829365515837 1.0 11.405248783250146 -4.751528229056656 24.991747601532037 0.8910586140172556 0.3472498916435578 0.7912252319099546 0.08493061142526619 187.14502521568218 471868.42632925225 0.021745272283674313 0.2848507552140009 1.7720328596012318e-05 4.751528229056656 -0.5438087223736978 DNHLHFYQDR ddPTM_PC-9_AZD4547_30min_R2 1 DNHLHFYQDR 10 0 Q8N4X5-2;Q8N4X5;Q8N4X5-4 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 0 75.566 0.010235 4034600.0 24110.0 20141.0 33099.0 44983.0 39605.0 30144.0 26971.0 32324.0 28470.0 29302.0 False True 31776.478480846356 26651.184371278214 32660.08563349759 34612.86433042206 34106.52938206245 28259.090914746743 29371.36675024975 27329.068531625784 29974.86607734305 28276.14589883468 1.1237910072516613 0.9425324252686278 1.15504021482799 1.224101207224586 1.2061944192849865 0.9993968419830286 1.0387330315571828 0.9665061366355474 1.0600760862030485 1.0 14.78729787057508 -6.78470502743489 24.98854559768968 1.0124609216666618 1.1264806604272313 0.3806184929789699 0.0747924611216701 291.6681290426571 313264.8987406913 0.029035211852300676 0.025621860594124687 1.6417044393378888e-07 6.78470502743489 0.11401973876056948 DNHLHFYQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DNHLHFYQDR 10 0 Q8N4X5-2;Q8N4X5;Q8N4X5-4 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 0 ; 84.31 0.0053106 5889800.0 29257.6 24447.8 35431.5 35410.0 38396.0 37093.6 35212.0 39078.4 31079.2 26739.9 False True 34210.33381605956 26874.81601411856 36276.32133471204 33426.09250076892 30872.579427992245 35148.346316449184 31876.46444719652 38052.633406987356 31533.674503930175 31587.632197068055 1.0830293832291407 0.8508018532839909 1.1484343336782041 1.0582019029546479 0.9773628879615047 1.1127249455472523 1.0091438398524621 1.2046687504016012 0.9982918095031229 1.0 14.947072176540011 -5.274124237039067 24.978309831540216 1.0674495579715493 0.9669156014705667 0.1645623770493444 0.08679588040087353 1072.2940842556252 2111501.496846045 0.021243189036425383 0.04468467773013508 5.319560627672376e-06 5.274124237039067 -0.10053395650098262 DNHLHFYQDR ddPTM_PC-9_Lapatinib_30min_R1 2 DNHLHFYQDR 10 0 Q8N4X5-2;Q8N4X5;Q8N4X5-4 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 0 ; 119.34 0.00033575 6113600.0 39722.0 33397.0 40469.0 35613.0 37174.0 38368.0 36070.0 30403.0 44415.0 33716.0 False True 39155.556995877334 33319.67129840558 37141.79503485753 38232.09882148538 34987.49840689599 36727.090080176415 37937.528108134524 31815.634371608285 39412.51498931548 39543.765676253955 0.9901828095089654 0.8426023857008148 0.9392579184020705 0.9668299962753362 0.8847791253200247 0.9287706785656745 0.9593807635501953 0.8045676436605426 0.9966808753619211 1.0 15.271162642214323 -8.46720939216568 24.999927659901907 1.0000025068981953 0.9147494544323932 0.27632593515142656 0.05425425216054696 306.9679404302883 137852.89841300962 0.04912910184139684 0.012685079552849856 3.4102844740349533e-09 8.46720939216568 -0.08525305246580206 DNIQGITKPAIR ddPTM_PC-9_AZD4547_30min_R2 2 DNIQGITKPAIR 12 1 P62805 P62805 HIST1H4A Histone H4 0 ; 115.92 0.00090812 63815000.0 191120.0 147619.0 147367.0 203647.0 171413.0 135739.0 120869.0 154805.0 112867.0 91442.0 False True 251892.18445704447 195333.95490311875 145412.8172921126 156699.33046478598 147615.2637537553 127251.21887197497 131626.10684572076 130883.44431500815 118832.91919745259 88240.64341277882 2.8546050290989378 2.213650618903249 1.6479120240759058 1.7758180856837804 1.6728715707933968 1.4420930531604297 1.4916721111153972 1.4832557793436703 1.3466914406048343 1.0 16.429155690028168 -1.5228787452803376 0.44504725235066406 1.3481826078074657 34.000386360439656 0.9057837492406412 0.14966155275064918 24.24988832408574 0.2953344989125927 0.09386836157745336 717.2301393632262 0.029999999999999995 1.5228787452803376 32.65220375263219 up DNIQGITKPAIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DNIQGITKPAIR 12 1 P62805 P62805 HIST1H4A Histone H4 0 ; 139.76 9.5133e-05 74660000.0 84402.0 159391.0 97954.0 174324.0 169163.0 162191.0 196039.0 149694.0 119436.0 104929.0 False True 98689.59158451314 175214.2851015782 100289.59485261375 164557.19144603336 136016.7244967562 153685.41843906263 177468.7667205487 145764.69111390374 121182.52554928735 123951.79708249282 0.7961933098786209 1.4135679290310652 0.8091015799139135 1.327590202960242 1.0973356393230336 1.239880518527548 1.431756302834715 1.1759788445575656 0.9776584801641686 1.0 16.919419662547256 -4.734706167253922 24.816858320769338 1.1718828413327147 0.7961912172622216 0.2518094643069573 0.18954301130709375 3644.866678448241 3383391.134619073 0.04517906215102299 3.8693629351186036 1.8420178430085607e-05 4.734706167253922 -0.37569162407049306 DNLAEDIMR ddPTM_PC-9_Lapatinib_30min_R1 3 DNLAEDIMR 9 0 P08670;B0YJC4 P08670 VIM Vimentin 0 ;; 145.9 0.0021526999999999996 11622800.0 53250.0 61763.0 56136.0 53038.0 59007.0 56376.0 59435.0 48683.0 55716.0 52502.0 False True 52490.645235145945 61619.99156820737 51520.71477122646 56938.59144958137 55536.32427222556 53964.92989887474 62512.253482311506 50944.989906029194 49440.67736450972 61576.90074548243 0.8524405190853471 1.0006997887552518 0.8366889880375518 0.9246745250289111 0.9019019080186488 0.8763826897025807 1.0151899937396198 0.8273392991407863 0.8029094801127502 1.0 15.910101635830458 -10.691110672234686 4.736973555846865 1.0000118257402901 0.8969870225669406 0.1830802571423772 0.06727942181908335 8.222430382562132e-06 1.4437608272854786e-06 0.06374616687640654 0.01545894195460526 2.0365230398511698e-11 10.691110672234686 -0.1030248031733495 DNLGEVPLT(ph)PTEEASLPLAVTK ddPTM_PC-9_AZD4547_30min_R2 1 DNLGEVPLTPTEEASLPLAVTK 22 0 H7C3Y7;H0Y764;A0A494C1V1;Q6ZNJ1-2;Q6ZNJ1-3;Q6ZNJ1 H7C3Y7 NBEAL2 Neurobeachin-like protein 2 1 DNLGEVPLT(0.616)PT(0.26)EEAS(0.123)LPLAVTK 61.538000000000004 0.012949 1900100.0 19901.0 19088.0 21819.0 25087.0 23891.0 22449.0 21078.0 27677.0 24485.0 19812.0 True False 26229.104033484986 25257.82271381551 21529.665803718653 19303.579740286288 20574.14703867832 21045.260481195244 22953.90116650344 23400.15560418904 25779.22711288178 19118.38791030347 1.3719307379127577 1.321127222248865 1.1261234945502738 1.0096865818839784 1.0761444497938184 1.100786351858324 1.2006190728106787 1.223960708087631 1.3483996262565938 1.0 14.22267325789618 -5.200423360069641 4.439591272932297 1.1379486594183383 1.3569376193802916 0.42506251357439884 0.09851236623516667 0.22237083336162394 8.932696943019721 0.027454286076282017 0.0778735903137575 6.303425727058073e-06 5.200423360069641 0.21898895996195322 DNLGEVPLT(ph)PTEEASLPLAVTK ddPTM_PC-9_Lapatinib_30min_R1 1 DNLGEVPLTPTEEASLPLAVTK 22 0 H7C3Y7;H0Y764;A0A494C1V1;Q6ZNJ1-2;Q6ZNJ1-3;Q6ZNJ1 H7C3Y7 NBEAL2 Neurobeachin-like protein 2 1 DNLGEVPLT(0.926)PT(0.074)EEASLPLAVTK 72.514 0.044292000000000005 0.0 7263.4 6732.3 5562.6 5419.4 9370.1 9186.4 9348.3 10762.0 11847.0 6815.8 True False 7159.822584055574 6716.711772981277 5105.264500256953 5817.960754588433 8818.969140325396 8793.519086544324 9832.309232416808 11262.041808612576 10512.666105559394 7993.901948517372 0.8956605460220218 0.8402294419219171 0.6386448736969842 0.7277998644538652 1.1032120730428836 1.100028389537009 1.2299762113344916 1.4088291151358623 1.3150856957295025 1.0 12.964684161741777 -6.53044967992952 1.848126348773442 1.2536374812791002 0.7692768599140472 0.7241412980248831 0.1258693599757108 0.17785969851941708 1.2280269944025934 0.049377931962481206 0.05341342373101511 2.948155048470499e-07 6.53044967992952 -0.4843606213650531 DNLTLWTSDQQDDDGGEGNN ddPTM_PC-9_AZD4547_30min_R2 6 DNLTLWTSDQQDDDGGEGNN 20 0 P61981 P61981 YWHAG 14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed 0 ;;;;; 265.12 4.2976999999999984e-157 33782200.0 201191.59999999998 200236.9 266840.1 344595.8 308303.7 261927.6 220966.2 297036.4 227643.3 242910.9 False True 265166.3437547504 264959.5620790029 263301.6259237756 265154.56226203777 265501.05296423635 245549.22576570534 240631.76373174984 251136.24959743192 239676.0600949919 234406.66332732324 1.1312235752636204 1.1303414259560356 1.1232685205543995 1.1311733143514715 1.132651474985987 1.047535177883671 1.0265568406463512 1.0713699262326328 1.0224797226020428 1.0 17.838654055343092 -6.794761298091176 5.121685890980471 1.0365002562496868 1.1297737134268764 0.8871176260880244 0.017160245926647482 0.05932214402714613 3.8197985191292485 0.005781932467884444 0.0052403735354354586 1.6041268270003105e-07 6.794761298091176 0.0932734571771896 DNLTLWTSDQQDDDGGEGNN ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DNLTLWTSDQQDDDGGEGNN 20 0 P61981 P61981 YWHAG 14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed 0 ;;;;; 228.38 2.1844999999999997e-35 41247200.0 237298.0 235126.0 265592.0 286433.0 290203.0 267631.0 273215.0 256635.0 245508.0 211249.0 False True 277467.86455086176 258467.75538640062 271924.7205432685 270385.08763831586 233339.8053896668 253595.9592225511 247334.09729469463 249898.6031772586 249098.09004449542 249546.77145383647 1.111887214305998 1.0357487451373997 1.0896743682920045 1.0835046515051159 0.9350543949346675 1.0162261677244888 0.9911332286679126 1.0014098828903792 0.998202014769708 1.0 17.928950713328632 -6.237592423071272 24.79375831272238 0.991742316528822 1.0777048743400701 0.7309034981098282 0.026687800093509458 372.7645520757042 387564.40063308744 0.0075273935734424275 0.009712099641259896 5.786388339656961e-07 6.237592423071272 0.08596255781124806 DNLTLWTSDQQDDDGGEGNN ddPTM_PC-9_Lapatinib_30min_R1 6 DNLTLWTSDQQDDDGGEGNN 20 0 P61981 P61981 YWHAG 14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed 0 ;;;;; 288.77 2.7365999999999994e-106 50140300.0 284346.0 241926.0 286052.0 236028.0 249113.0 258183.0 226264.0 227945.0 278351.0 203836.0 False True 280291.1738973297 241365.83521088902 262533.9087526515 253386.28648632605 234460.66311500175 247141.11494396854 237978.842801745 238536.15685413414 247000.1792140254 239068.78100560312 1.172429008582097 1.0096083403095282 1.0981522039320493 1.0598886455207523 0.9807247191740466 1.0337657384808276 0.9954409011529088 0.9977720882282137 1.0331762188900624 1.0 17.867066221261638 -1.5228787452803376 0.5439195530810079 1.0088434968568938 6.80259652526889 0.5922679229387198 0.035649565671109176 95.76398000500292 0.8940832868257033 0.017572270192848106 646.6373739309804 0.029999999999999995 1.5228787452803376 5.793753028411996 DNLTLWTSDQQDEEAGEGN ddPTM_PC-9_AZD4547_30min_R2 1 DNLTLWTSDQQDEEAGEGN 19 0 Q04917 Q04917 YWHAH 14-3-3 protein eta 0 185.2 3.5047000000000003e-10 2002400.0 11148.0 11459.0 14590.0 19949.0 16007.0 14708.0 11072.0 15284.0 13034.0 14670.0 False True 14692.832107195158 15162.897657041709 14396.527067063347 15350.066258977608 13784.704350932312 13788.306434915561 12057.386550693907 12922.208991380036 13722.950630561621 14156.407765200487 1.0378926879538832 1.0710978313520603 1.0169618808560408 1.0843193070993187 0.9737430977947737 0.9739975468077573 0.8517264231631962 0.9128169522741229 0.9693808526973632 1.0 13.789167602822518 -6.573132978364909 2.192384033699416 0.9279851567026052 1.0511533159667716 0.5956813938059273 0.042469323868060675 0.19822000766246248 1.9308604358678363 0.015375029070372971 0.016022191911680604 2.672188075427821e-07 6.573132978364909 0.12316815926416647 DNLTLWTSDQQDEEAGEGN ddPTM_PC-9_Lapatinib_30min_R1 2 DNLTLWTSDQQDEEAGEGN 19 0 Q04917 Q04917 YWHAH 14-3-3 protein eta 0 ; 150.11 3.4358e-14 1982000.0 44817.0 48844.0 52391.0 43520.0 48578.0 52633.0 43340.0 46444.0 53176.0 42219.0 False True 44177.901361568765 48730.90471896644 48083.614215108384 46720.605978464155 45720.73754802265 50382.009283515574 45583.93313575133 48601.95779215781 47186.75891189552 49516.49789671864 0.8921854985325274 0.9841347185055214 0.9710624995208877 0.9435361538676231 0.9233435216558897 1.0174792528462375 0.9205807169729604 0.9815305980146581 0.9529502472149286 1.0 15.595621661676287 -9.557329040460596 0.006242932423949371 1.9556635597099277 3.309111461214451e-07 0.1776391508680435 0.03377544428523786 16849.87559584905 31.17828678861779 4996.584253408896 4769.887508478112 2.7712197120336685e-10 9.557329040460596 -1.9556632287987816 DNLTLWTSENQGDEGDAGEGEN ddPTM_PC-9_AZD4547_30min_R2 4 DNLTLWTSENQGDEGDAGEGEN 22 0 P31946-2;P31946 P31946-2 YWHAB 14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed 0 ;;; 230.86 2.6277e-41 28773700.0 97376.8 98222.2 138121.0 178576.0 146698.0 129291.6 125123.0 147495.0 116916.8 134755.0 False True 128340.59683673484 129970.60531019133 136289.42529334183 137408.06217169698 126331.51489180171 121206.97581319883 136258.70460463074 124703.0368479195 123096.78335762199 130037.26846622978 0.9869524202599229 0.9994873534577837 1.0480797305330642 1.056682163447484 0.9715023729878605 0.9320941391865353 1.0478434852698912 0.9589792089511973 0.9466269540227215 1.0 16.988565630966725 -6.2879614649508655 24.11507690389466 0.9755027574457862 1.0229408661656272 0.2951057985156492 0.03529323024859697 637.8423383966126 579952.8295493353 0.011362571625560761 0.012888813249661036 5.15274362966007e-07 6.2879614649508655 0.047438108719841 DNLTLWTSENQGDEGDAGEGEN ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DNLTLWTSENQGDEGDAGEGEN 22 0 P31946-2;P31946 P31946-2 YWHAB 14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed 0 ;;; 242.91 9.140699999999999e-61 27888800.0 197385.0 208948.0 238774.0 246132.0 268234.0 249166.0 264443.0 246854.0 231848.0 197448.0 False True 230798.38196854587 229690.97655077526 244467.27771543816 232342.02201071096 215675.47323388004 236099.29632832567 239393.04463847572 240374.3440634331 235238.3383866768 233243.7594024916 0.9895157862306365 0.9847679403692617 1.0481192651914815 0.9961339270380025 0.9246784299240554 1.0122427152312636 1.026364200490238 1.0305713845429698 1.0085514784588225 1.0 17.83147895573026 -6.9790669262923855 24.999680667512344 1.018974286702777 0.9897794234807322 0.17622752238623562 0.02892231433999574 435.5533854616582 520166.0777527434 0.010850865252976098 0.0095685673974063 1.0493807029698914e-07 6.9790669262923855 -0.029194863222044676 DNLTLWTSENQGDEGDAGEGEN ddPTM_PC-9_Lapatinib_30min_R1 4 DNLTLWTSENQGDEGDAGEGEN 22 0 P31946-2;P31946 P31946-2 YWHAB 14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed 0 ;;; 319.82 2.034199999999999e-167 31536900.0 249198.0 220211.0 237536.0 200671.0 205154.0 215449.0 184381.0 201397.0 223894.0 174514.0 False True 245644.39082268323 219701.11495922378 218006.70699547653 215429.01475883223 193087.24506828267 206234.74850614896 193927.34599683832 210754.63985589586 198676.700011658 204678.5123747114 1.2001474310746127 1.073396090338052 1.0651177032025951 1.0525238446351395 0.9433684211794141 1.0076033195345317 0.9474729112834738 1.0296862011096735 0.9706768810588886 1.0 17.643000127273865 -2.368322503277552 0.5487778940529946 0.9829750175536363 4.385426897864089 0.8062226421514154 0.03168246836972181 20.315211666358696 0.4931998135724992 0.015494474397528685 74.82034195726816 0.004282304021510933 2.368322503277552 3.402451880310452 DNPAQDFSTLYGS(ph)SPLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DNPAQDFSTLYGSSPLER 18 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 DNPAQDFSTLYGS(0.845)S(0.155)PLER;DNPAQDFSTLYGS(0.5)S(0.5)PLER 268.65 2.268e-78 3493500.0 22357.1 26061.3 26364.6 29462.0 30912.5 23891.9 28614.0 20858.5 27176.7 19846.8 True False 26141.71545714703 28648.493630868532 26993.23205230228 27811.339657092765 24855.417532237996 22638.96670471382 25903.474772579833 20310.986476407572 27574.10782423483 23444.86773281765 1.1150293426716325 1.221951599699876 1.1513492999799568 1.1862442549915952 1.0601645449867856 0.9656256952571439 1.1048676012072645 0.8663297531841763 1.1761255443398027 1.0 14.51698451948486 -6.377472994684108 3.9792415746519954 1.0188121248897417 1.1711606296305488 0.4222205448718981 0.0807719354679994 0.2107178142488781 5.793823869685026 0.023884479230470806 0.027297321722234875 4.1930206893108565e-07 6.377472994684108 0.15234850474080708 DNPAQDFSTLYGSS(ph)PLER ddPTM_PC-9_AZD4547_30min_R2 2 DNPAQDFSTLYGSSPLER 18 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 DNPAQDFSTLYGS(0.053)S(0.947)PLER;DNPAQDFSTLYGS(0.003)S(0.997)PLER 264.69 4.634799999999999e-78 9942100.0 25993.0 27131.0 36278.0 40496.0 35386.0 32971.0 28418.0 42671.0 30432.0 28261.6 True False 34258.233312013246 35900.56517437807 35796.93001637589 31160.27285696313 30473.26470682142 30909.31815784616 30947.146947039302 36077.17743203204 32040.573391840666 27272.169986161553 1.2561608896320522 1.3163809551126566 1.312580921669965 1.1425666851143301 1.1173758715307278 1.133364824784026 1.134751908731227 1.32285687022112 1.1748450309637515 1.0 14.735141876418767 -14.522878745004418 0.0316209250309433 8.680470022213604e-10 1.8852204746794625 0.43121160798033054 0.07658864486476936 1533.9825423907575 3.634054692705269 173.19882012488105 66.66478778431454 3.000000001905987e-15 14.522878745004418 1.8852204738114156 DNPAQDFSTLYGSS(ph)PLER ddPTM_PC-9_Lapatinib_30min_R1 2 DNPAQDFSTLYGSSPLER 18 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 DNPAQDFSTLYGS(0.417)S(0.583)PLER;DNPAQDFSTLYGS(0.095)S(0.905)PLER 159.18 8.4079e-06 9173700.0 28867.0 32214.0 35572.0 23618.6 32768.0 38231.0 29731.0 28953.0 29392.0 28410.0 True False 28455.351286440527 32139.410462222248 32647.407471890892 25355.5906333399 30840.6506643667 36595.94925081383 31270.325705099738 30298.262078123036 26081.563448518755 33320.630646054524 0.8539859760970613 0.9645498851333373 0.9797956052718544 0.7609577052330563 0.9255722375716356 1.0982970172308888 0.9384674028912007 0.9092943768070799 0.7827451924775336 1.0 15.024128085814896 -4.741453208748924 23.682739721318963 0.9278569509516261 0.8539854749999203 0.05431672173513813 0.09363417456633835 2671.1659259669873 3164889.7871442423 0.024110289514844927 0.8603577292012287 1.8136220665046674e-05 4.741453208748924 -0.07387147595170585 DNPGVVTCLDEAR ddPTM_PC-9_Lapatinib_30min_R1 1 DNPGVVTCLDEAR 13 0 P22314;P22314-2;Q5JRR9;Q5JRS0 P22314;Q5JRS0 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 89.663 0.027620999999999996 3577200.0 14664.0 13998.0 15270.0 15369.0 15238.0 18043.0 17600.0 14749.0 18579.0 19622.0 False True 14454.888670951754 13965.588491034548 14014.55954390458 16499.287529481055 14341.730799060673 17271.342950287308 18511.241882538612 15434.29238387168 16486.437374456636 23013.63655532848 0.6281010233302277 0.606839708164289 0.608967622748857 0.7169352609620873 0.6231840311104613 0.7504829977115621 0.80435970377974 0.6706585613605724 0.716376889624575 1.0 14.490201352064169 -14.522878745277936 0.12827394035633255 2.0612393845807637 0.5453547660707857 0.7994630244024621 0.0513144442419835 65.98770641404752 0.5346135811241206 18.008479682371 0.4276371033895383 3.000000000016591e-15 14.522878745277936 -1.5158846185099781 DNPS(ph)PEPQLDDIKR ddPTM_PC-9_Lapatinib_30min_R1 2 DNPSPEPQLDDIKR 14 1 Q96JC9-2;Q96JC9 Q96JC9-2 EAF1 ELL-associated factor 1 1 DNPS(1)PEPQLDDIKR;DNPS(1)PEPQLDDIKR 70.334 0.01267 6128200.0 26768.0 35676.0 38155.0 31795.0 35401.0 40020.0 37752.0 45184.0 42280.0 28920.0 True False 26386.28341135001 35593.39441392689 35018.043182559224 34133.31036501073 33318.782781043876 38308.43789117649 39706.61383804534 47283.4135923017 37517.981171862164 33918.78346652227 0.7779254063576068 1.0493711972027966 1.0324085832005714 1.0063247226628926 0.982310666121897 1.1294166233581695 1.1706379115051588 1.3940185572684316 1.1061122286090328 1.0 15.049796806576474 -6.890526013826938 2.4167354461836106 1.1993290046932572 0.9765549017393065 0.39089939424868947 0.11667012001951663 0.2803186965524783 3.3313690420055395 0.04574079060715845 0.03902017350713687 1.286690179201838e-07 6.890526013826938 -0.22277410295395073 DNPS(ph)PGPSR ddPTM_PC-9_AZD4547_30min_R2 1 DNPSPGPSR 9 0 Q9NQS1 Q9NQS1 AVEN Cell death regulator Aven 1 DNPS(0.998)PGPS(0.002)R 71.888 0.033767 9855200.0 47457.0 49916.0 57179.0 65672.0 54804.0 56175.0 49718.0 65934.0 52659.0 54010.0 True False 62547.33883307861 66050.37083941817 56420.7690999051 50532.33502228565 47195.41058589954 52662.368369688724 54142.80568347178 55745.41531259177 55442.44723452084 52119.12633936454 1.2000841768876285 1.2672962015775702 1.0825348209509722 0.9695545296222585 0.9055295800354539 1.0104230839708817 1.0388279598343688 1.069576933228222 1.0637639409670276 1.0 15.669525280101118 -5.426547615147624 3.79055159386552 1.0087991189116279 1.2321192787095578 0.7766909653460611 0.04766747782273818 0.11428723243233951 2.9561498233598624 0.014601276838583716 0.032430120924847684 3.745004853275163e-06 5.426547615147624 0.22332015979792996 DNPS(ph)PGPSR ddPTM_PC-9_Lapatinib_30min_R1 1 DNPSPGPSR 9 0 Q9NQS1 Q9NQS1 AVEN Cell death regulator Aven 1 DNPS(1)PGPSR 92.11200000000001 0.0072805000000000005 8076000.0 45256.0 51053.0 53786.0 51735.0 63897.0 77346.0 71085.0 61912.0 72679.0 62619.0 True False 44610.64114106605 50934.78991518695 49363.92269996411 55539.764482900755 60138.70408633545 74038.09188233224 74765.43347842374 64788.65754086805 64493.125676200856 73442.61071542736 0.607421777446361 0.693531853225468 0.6721428094548213 0.7562335263121858 0.8188530268805205 1.0081081154537415 1.0180116522290037 0.8821671358049713 0.8781431521558564 1.0 16.164329723694074 -6.290868731578357 1.680169941118966 0.9526276848378995 0.6610890898740552 0.8521958615075902 0.05430724188536088 0.14451320664174844 0.8079807374068759 0.021033230322220722 0.027538001903849512 5.118365181846794e-07 6.290868731578357 -0.29153859496384427 DNQES(ph)SDAELSSSEYIK ddPTM_PC-9_Lapatinib_30min_R1 1 DNQESSDAELSSSEYIK 17 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 DNQES(0.675)S(0.324)DAELS(0.001)SSEYIK 206.45 2.5651999999999996e-17 5914300.0 13986.0 17287.0 21052.0 18847.0 16959.0 16412.0 14761.0 14174.0 17129.0 14251.0 True False 13786.557075281726 17246.973013610113 19321.18582307003 20233.071251748923 15961.504962676845 15710.097018240604 15525.252353872309 14832.57578473098 15199.751643633565 16714.26636173612 0.824837703127863 1.0318713750484145 1.1559697210104247 1.2105270320490036 0.9549629410727491 0.9399214227078277 0.9288623274195381 0.8874200915385143 0.9093879034039013 1.0 14.028792411769901 -6.497794890157477 24.321398395354926 0.9282189739354455 1.0639343052633323 0.26275556836916236 0.09770578124212474 717.9043613501425 696083.3057106865 0.03232535116099483 0.03647873235739877 3.178374808198623e-07 6.497794890157477 0.13571533132788682 DNQESS(ph)DAELSSSEYIK ddPTM_PC-9_AZD4547_30min_R2 3 DNQESSDAELSSSEYIK 17 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 DNQES(0.094)S(0.906)DAELSSSEYIK;DNQES(0.238)S(0.762)DAELSSSEYIK;DNQES(0.088)S(0.912)DAELSSSEYIK 159.4 2.3908000000000003e-17 9127300.0 70016.0 64173.0 77868.0 106290.0 96786.0 88675.0 80638.0 100846.0 83636.0 87032.0 True False 92279.63157672925 84915.66727858789 76835.4194419527 81786.48266412997 83348.93454796882 83130.13823199208 87814.62578349504 85262.56791054107 88056.82821372195 83985.036170479 1.0987627770905912 1.0110809157266996 0.9148703500702974 0.9738220806158107 0.9924260124003641 0.98982083026372 1.045598475486067 1.0152114209663354 1.0484823514867307 1.0 16.35784468165817 -7.2456376587295415 23.11314611769059 1.0285906797029436 0.9924794604984744 0.09707201035796087 0.04438679609644737 677.9138750681474 991584.8481873268 0.017947590978986648 0.013839875527132877 5.680183177230371e-08 7.2456376587295415 -0.03611121920446925 DNQESS(ph)DAELSSSEYIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DNQESSDAELSSSEYIK 17 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 DNQES(0.011)S(0.989)DAELSSSEYIK;DNQES(0.262)S(0.727)DAELS(0.004)S(0.004)S(0.004)EY(0.001)IK 211.67 4.9423e-18 10547600.0 47770.0 46220.0 51162.0 63706.0 71770.0 56481.0 65784.0 54909.0 50818.0 52912.0 True False 55856.51749949291 50808.416142661496 52381.89611296549 60136.75935763869 57707.18370525577 53519.03693088208 59552.46328508392 53467.69693089451 51561.117111789354 62504.52674883849 0.8936395554827696 0.8128757833304554 0.838049639563728 0.9621184654238855 0.9232480702900151 0.8562425749728056 0.9527704053241323 0.8554211944639368 0.8249181266338842 1.0 15.931673057029913 DNQESS(ph)DAELSSSEYIK ddPTM_PC-9_Lapatinib_30min_R1 3 DNQESSDAELSSSEYIK 17 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 DNQES(0.033)S(0.966)DAELS(0.001)SSEYIK;DNQES(0.095)S(0.905)DAELSSSEYIK;DNQES(0.029)S(0.971)DAELSSSEYIK 224.99 6.1916e-29 19315400.0 73696.0 83964.0 96512.0 87282.0 89512.0 87097.0 82444.0 94323.0 81919.0 77126.0 True False 72645.08152580875 83769.58651673263 88577.15590709346 93701.00944421679 84247.08014736301 83372.06434302348 86712.54691840988 98705.59092304074 72692.41957468716 90457.12633606473 0.8030885400440317 0.9260695083935491 0.9792170003059036 1.0358610011122888 0.9313481818377664 0.9216749162833345 0.9586038207344433 1.0911864539708178 0.8036118603262009 1.0 16.464946544360686 -4.788010642980674 2.798463297851937 0.9676158542873918 0.7740822453198355 0.3144244889107577 0.07181407601383713 0.49244353967814125 5.360328867700175 0.017628166455660035 0.22101457907974184 1.6292561049997577e-05 4.788010642980674 -0.19353360896755634 DNS(ph)PEPNDPEEPQEVSSTPSDKK ddPTM_PC-9_Lapatinib_30min_R1 1 DNSPEPNDPEEPQEVSSTPSDKK 23 1 G5E9C0;Q9HB58-2;Q9HB58-5;Q9HB58-3;Q9HB58-7;Q9HB58;Q9HB58-6 G5E9C0 SP110 Sp110 nuclear body protein 1 DNS(1)PEPNDPEEPQEVSSTPSDKK 76.028 0.00016683 3688500.0 6510.7 12178.0 5820.5 6253.4 9445.0 8395.1 7064.3 7601.6 10105.0 6755.0 True False 6417.856224083845 12149.802589214094 5341.960957779738 6713.295896730875 8889.463669584462 8036.06114293393 7430.054888114636 7954.798087005142 8966.868489632616 7922.59274952828 0.81007019128504 1.5335639446994807 0.6742692861623872 0.8473609724708608 1.1220397098050698 1.0143221287516522 0.9378312281111546 1.00406499974125 1.1318098472455893 1.0 12.95175692895104 -8.046318669438593 22.314488169308824 1.0665827651806805 0.9982794436576818 0.01712654702146499 0.2185467871370777 794.8813741030483 382929.0260475921 0.14410193873968122 0.054475417598958964 8.98837805126886e-09 8.046318669438593 -0.06830332152299867 DNS(ph)PPPAFKPEPPK ddPTM_PC-9_AZD4547_30min_R2 2 DNSPPPAFKPEPPK 14 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 DNS(1)PPPAFKPEPPK;DNS(1)PPPAFKPEPPK 82.774 0.0041746000000000005 194940000.0 181827.0 238700.0 172708.0 159210.0 160453.0 196887.0 204740.0 194569.0 203486.0 167871.0 True False 239644.2037634535 315855.10696708754 170417.77907459767 122506.59426997957 138176.87057038437 184575.6247655164 222961.46336606512 164502.8318008262 214241.85453509729 161993.887385956 1.4793410271863712 1.9497964525942382 1.0520012935338199 0.7562420795428126 0.8529758301384127 1.1393987004321875 1.3763572623876341 1.0154878955950515 1.3225304855155349 1.0 17.30557985048285 -5.274216244837376 24.606999945882162 1.0601943361848942 1.7145687229284334 0.6131156203391979 0.20657503062243493 361.7462905849949 696688.7056624988 0.056851850190273154 0.1196315348297006 5.318433767350826e-06 5.274216244837376 0.6543743867435392 DNS(ph)PPPAFKPEPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 DNSPPPAFKPEPPK 14 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 DNS(1)PPPAFKPEPPK;DNS(1)PPPAFKPEPPK;DNS(1)PPPAFKPEPPK;DNS(1)PPPAFKPEPPK;DNS(1)PPPAFKPEPPK;DNS(1)PPPAFKPEPPK;DNS(1)PPPAFKPEPPK 112.91 0.0012490000000000001 323352100.0 612186.0 984900.0 506914.0 597687.0 646294.0 424300.0 657608.0 453485.0 398741.0 434084.0 True False 715816.9985753518 1082674.3630226585 519000.75224205124 564200.535117398 519657.3301602986 402048.9610625395 595314.6095703734 441581.4992570742 404571.83278113976 512779.99299294583 1.3959534466181855 2.1113818359086265 1.0121314390852043 1.100277980473313 1.013411867197103 0.7840574253217215 1.1609552199876156 0.8611519663232042 0.7889774139193168 1.0 18.9679804482247 -5.319418271399973 8.83840701633302 0.9662543379707272 1.7525434128587503 0.716964715082012 0.19819139442918254 0.17195459899313262 25.098656457065857 0.04897204688870447 0.10246172207615664 4.792716371406672e-06 5.319418271399973 0.786289074888023 DNS(ph)PPPAFKPEPPK ddPTM_PC-9_Lapatinib_30min_R1 3 DNSPPPAFKPEPPK 14 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 DNS(1)PPPAFKPEPPK;DNS(1)PPPAFKPEPPK;DNS(1)PPPAFKPEPPK 92.633 0.017539 24502500.0 129137.0 208873.0 130623.0 161238.0 195571.0 170589.0 176392.0 172666.0 147464.0 148591.0 True False 127295.48269917454 208389.36740161877 119883.68115936164 173095.98039420004 184067.89828737988 163293.30613238164 185524.7146673154 180688.69270822324 130855.05145523843 174274.7563649383 0.7304298416726098 1.1957518790916746 0.6879004375614814 0.9932361060469947 1.0561936916551147 0.9369877172023636 1.0645529997403596 1.0368035880644348 0.7508548810203052 1.0 17.411004085181993 -4.682493369522416 22.544765360186158 0.966953629810017 0.7303708798648056 0.20237075771800273 0.1421151748072877 52769.19152336079 15057778.76450456 0.03354365733372383 493.27161981363275 2.077335440506792e-05 4.682493369522416 -0.23658274994521133 DNS(ph)PSLK ddPTM_PC-9_Lapatinib_30min_R1 1 DNSPSLK 7 0 A0A087WU05;A0A087WY48;Q8IY22-3;Q8IY22-2;Q8IY22 A0A087WU05 CMIP C-Maf-inducing protein 1 DNS(0.958)PS(0.042)LK 70.056 0.044964 5872600.0 54930.0 106790.0 92643.0 90356.0 110600.0 112910.0 106810.0 139270.0 93868.0 95390.0 True False 54146.688127071735 106542.73431615811 85026.25015232153 97001.08165878021 104094.72544796632 108081.10250606551 112340.09917465619 145740.9926301314 83295.59736613903 111878.03440081443 0.483979615990443 0.9523114603037978 0.7599905612187139 0.8670252581598277 0.9304304102719251 0.9660618644662095 1.0041300759019984 1.302677450588732 0.7445214586781538 1.0 16.771567286696516 -4.141747978912914 0.48507375766273764 1.0256144032083632 5.7364495720932326e-11 0.42941397217722554 0.1527537764177792 8.15969130107035 0.9283343353648787 0.09199507944426757 5.440912644516994 7.215260592910753e-05 4.141747978912914 -1.0256144031509986 DNS(ph)TMGYMAAK ddPTM_PC-9_Lapatinib_30min_R1 1 DNSTMGYMAAK 11 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 DNS(0.863)T(0.037)MGY(0.1)MAAK 58.172 0.043759 2762400.0 29092.0 33144.0 37387.0 34217.0 37370.0 31904.0 37256.0 34713.0 37502.0 29390.0 True False 28677.142745180587 33067.257104361306 34313.18517799349 36733.432324565874 35171.97007224681 30539.540291856454 39184.933384991986 36325.89270603684 33278.12984643269 34470.0223402866 0.8319444200552307 0.9593047772909092 0.9954500417567234 1.065663142365705 1.0203640057157668 0.8859739048142007 1.1367829413674289 1.0538401265722765 0.9654223463481514 1.0 15.073054613276687 -4.6910000558795995 1.6503947265028296 1.0199554580670525 0.733448484953188 0.44643355611316526 0.06212677290354101 1.181747725986651 2.6568042847089046 0.017504295038680645 0.5827001491592632 2.037041815604557e-05 4.6910000558795995 -0.2865069731138644 DNSTMGYMAAK ddPTM_PC-9_Lapatinib_30min_R1 2 DNSTMGYMAAK 11 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ; 102.95 0.018709 3219300.0 20564.8 19215.5 21305.9 19711.3 18764.7 18134.4 18259.4 15279.9 16620.4 15751.400000000001 False True 20271.542180877554 19171.007690346807 19554.211145152367 21160.93475696921 17660.997238819633 17358.833985351106 19204.782388069638 15989.859936017403 14748.435531428995 18474.008502578796 1.0973006847998277 1.0377286384636402 1.05847148129345 1.145443597366286 0.9559916158073829 0.9396354874973657 1.0395568663611274 0.8655327799478587 0.7983343479229348 1.0 14.173209316759989 -6.845766677453229 0.9375832508829515 0.8951625491054689 1.0802359838768396 0.49973711591946346 0.07107323248390462 0.4753141752653939 0.8922498859036495 0.045534685583731395 0.038402470274392475 1.4263736999545355e-07 6.845766677453229 0.18507343477137073 DNTFFRES(ph)PVGR ddPTM_PC-9_AZD4547_30min_R2 2 DNTFFRESPVGR 12 1 F8WF16;B7Z8L1;F8W6A0;F8W0Q9;Q8NEY8-5;Q8NEY8-6;Q8NEY8-9;Q8NEY8-8;Q8NEY8-2;Q8NEY8-3;Q8NEY8;F8VPY7;F8VWU8 F8WF16 PPHLN1 Periphilin-1 1 DNT(0.023)FFRES(0.977)PVGR;DNTFFRES(1)PVGR 72.615 0.011612 281820000.0 136166.0 141418.0 207459.0 251679.0 231662.0 220704.0 161440.0 199653.0 191853.0 190962.0 True False 179463.95557125375 187128.6029202829 204707.95810869738 193658.29495178838 199499.73007719626 206903.34399045425 175807.84724928 168801.2164195234 201993.95790433776 184276.47850430888 0.9738842256368461 1.0154774197940153 1.110874050612546 1.0509116330181019 1.0826109316633779 1.1227875943245589 0.9540438838219341 0.91602150089696 1.0961461796092147 1.0 17.491512408070513 -10.767811122871075 6.5308434656255825 0.9999995792669193 1.035911743301887 0.025327539215621697 0.06673960621346675 4.3275602348671063e-07 5.009565862909613e-08 0.06839732732915421 0.016588594242118546 1.7068245352631425e-11 10.767811122871075 0.035912164034967664 DNTFFRES(ph)PVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DNTFFRESPVGR 12 1 F8WF16;B7Z8L1;F8W6A0;F8W0Q9;Q8NEY8-5;Q8NEY8-6;Q8NEY8-9;Q8NEY8-8;Q8NEY8-2;Q8NEY8-3;Q8NEY8;F8VPY7;F8VWU8 F8WF16 PPHLN1 Periphilin-1 1 DNTFFRES(1)PVGR;DNTFFRES(1)PVGR;DNT(0.001)FFRES(0.999)PVGR 84.62 0.0047703 169480200.0 72797.0 71137.0 80522.0 88559.0 94127.0 80106.0 83598.0 90276.0 82852.0 63347.0 True False 85120.09429371139 78199.01123194526 82441.94986138563 83597.32634215163 75683.49004632338 75905.10034144651 75678.9922428926 87906.3506553285 84063.55375941552 74831.30964542397 1.1374930453180514 1.0450039108292852 1.101703955897918 1.1171437027931759 1.0113880193322464 1.014349484208021 1.011327913429355 1.1747268766490722 1.1233740817545095 1.0 16.191354403929452 -3.5182740938959083 12.348125933969776 1.074588245382391 1.0788986759021308 0.0 0.06080668679449163 0.0 0.0 0.014375990910613774 0.0 0.00030319770251804374 3.5182740938959083 0.004310430519739894 DNTFFRES(ph)PVGR ddPTM_PC-9_Lapatinib_30min_R1 2 DNTFFRESPVGR 12 1 F8WF16;B7Z8L1;F8W6A0;F8W0Q9;Q8NEY8-5;Q8NEY8-6;Q8NEY8-9;Q8NEY8-8;Q8NEY8-2;Q8NEY8-3;Q8NEY8;F8VPY7;F8VWU8 F8WF16 PPHLN1 Periphilin-1 1 DNT(0.084)FFRES(0.916)PVGR;DNT(0.002)FFRES(0.998)PVGR 55.815 0.037342 192507000.0 102073.0 84572.0 92235.0 92844.0 77895.0 81625.0 79433.0 80739.0 86229.0 64307.0 True False 100617.4203021043 84376.17873008839 84651.7943373963 99672.05747850478 73313.36924746222 78134.08902716852 83545.6520713461 84490.42869221064 76516.98198837512 75422.37926630868 1.3340525886465942 1.118715420421368 1.1223697152074652 1.321518340419532 0.9720373443616813 1.0359536491322432 1.1077037463423818 1.1202302223042262 1.0145129699263598 1.0 16.202705041850326 -1.5228787452843973 0.278713151195541 1.0286120670901804 2.902256612910629 0.44417019925403567 0.0884623317582642 55.28773723933824 0.7784740815802283 0.10146665511345512 50.36666480289654 0.029999999999719567 1.5228787452843973 1.8736445458204485 DNTINLIHTFR ddPTM_PC-9_AZD4547_30min_R2 1 DNTINLIHTFR 11 0 H7C3F9;O15144 H7C3F9 ARPC2 Actin-related protein 2/3 complex subunit 2 0 93.348 0.0060016 1904700.0 13363.0 16420.0 16762.0 25076.0 22654.0 19379.0 18800.0 21910.0 16158.0 21892.0 False True 17612.156032333045 21727.443889399136 16539.72492790376 19295.115620337983 19508.883136504053 18167.22806650999 20473.163579574193 18524.312941712695 17012.078892789224 21125.567743406194 0.8336891224062004 1.028490412816517 0.7829245172862259 0.9133537074458252 0.9234726078589416 0.859964015508195 0.9691177926313658 0.8768669872787009 0.8052838673696289 1.0 14.366702493469253 DNWSPALT(ph)IS(ph)KVLLS(ph)ICS(ph)LLT(ph)DCNPGK ddPTM_PC-9_Lapatinib_30min_R1 1 DNWSPALTISKVLLSICSLLTDCNPGK 27 1 B7Z306 B7Z306 UBE2E1 5 DNWS(0.122)PALT(0.939)IS(0.939)KVLLS(1)ICS(1)LLT(1)DCNPGK 43.349 0.01725 3919400.0 16851.0 12489.0 16598.0 15172.0 16648.0 15974.0 12614.0 13576.0 16046.0 10606.0 True False 16610.701649905073 12460.082487821868 15233.376510132823 16287.79949230832 15668.797371227323 15290.82925721274 13267.091199223989 14206.790521624634 14238.730508129138 12439.232968393324 1.335347741465328 1.0016761097313251 1.2246234594077545 1.309389375831594 1.25962729462821 1.2292421322170746 1.0665521928027362 1.1420953814212238 1.1446630627714853 1.0 13.602609907878739 -8.355436625734566 0.622324218770233 1.0076658392885722 1.2183613450218245 0.3347780683230662 0.09322021357875558 0.9885251708311588 0.906294084556147 0.09727412495442181 0.04337598962004269 4.411267296837135e-09 8.355436625734566 0.21069550573325224 DNYGLNQDLESESVNPILS(ph)PNQFLK ddPTM_PC-9_AZD4547_30min_R2 2 DNYGLNQDLESESVNPILSPNQFLK 25 0 Q8IZT6-2;Q8IZT6 Q8IZT6-2 ASPM Abnormal spindle-like microcephaly-associated protein 1 DNYGLNQDLESESVNPILS(1)PNQFLK;DNYGLNQDLESESVNPILS(1)PNQFLK 189.22 2.6779000000000002e-21 1967160.0 8066.89 9473.5 10159.7 5872.02 7129.5 11760.67 9472.45 10926.52 9158.92 8920.83 True False 10631.993218264397 12535.623610610393 10024.97573976995 4518.316510804636 6139.6919891279995 11025.273445738267 10315.479699432848 9238.077400451048 9643.041812894237 8608.514456989325 1.2350555106092889 1.4561889479586823 1.1645418951037003 0.5248659955651438 0.7132115558153163 1.2807405390121351 1.198288014845305 1.0731325882772462 1.1201748990576381 1.0 13.071548582627397 -5.523312006938443 24.99977011036195 0.987923906685361 1.3368080996686693 0.30733337771483826 0.2166532242298985 18.658273377516494 1076593.5630375384 0.06548714571770257 0.11481034358143638 2.997008626871711e-06 5.523312006938443 0.3488841929833083 DPAQPMS(ph)PGEATQSGAR ddPTM_PC-9_AZD4547_30min_R2 5 DPAQPMSPGEATQSGAR 17 0 Q9BQG0;Q9BQG0-2 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 DPAQPMS(0.995)PGEAT(0.005)QSGAR;DPAQPMS(0.999)PGEAT(0.001)QSGAR;DPAQPMS(0.94)PGEAT(0.056)QS(0.004)GAR;DPAQPMS(0.897)PGEAT(0.101)QS(0.002)GAR;DPAQPMS(0.567)PGEAT(0.333)QS(0.1)GAR 136.66 4.5998e-05 84611300.0 56111.7 66228.0 74397.3 79941.9 63208.2 76592.4 72086.9 90105.6 69913.7 61573.6 True False 73954.05340413547 87634.9058408725 73410.7431916677 61512.530045042964 54432.83248295114 71803.06512004526 78502.49444917058 76181.84994070219 73609.19545035258 59417.92700554525 1.244642099298308 1.4748899912427753 1.235498222360005 1.035252038316689 0.9161011705755256 1.208441100837196 1.3211920779707484 1.2821357758508207 1.2388381614774764 1.0 15.858610652326457 -1.522931752336072 0.016989969321775617 3.918548962866804e-06 2.683202627843623 0.12909811319287356 0.14737406224270574 12283.695078045244 16.16282599326993 990.8331728285862 1636.3403937679007 0.029996338625755146 1.522931752336072 2.6831987092946603 DPAQPMS(ph)PGEATQSGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DPAQPMSPGEATQSGAR 17 0 Q9BQG0;Q9BQG0-2 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 DPAQPMS(0.976)PGEAT(0.024)QSGAR;DPAQPMS(0.999)PGEAT(0.001)QSGAR;DPAQPMS(0.998)PGEAT(0.002)QSGAR;DPAQPMS(0.981)PGEAT(0.019)QSGAR 111.73 0.00027039 67715900.0 51866.0 75076.0 64402.0 52992.0 66912.0 46851.0 59373.0 39299.3 48718.0 39541.2 True False 60645.8893998053 82529.04912000132 65937.58792594515 50023.03004238199 53801.07393181103 44394.0510835282 53748.759616704534 38267.735016050276 49430.40858459905 46709.70655203304 1.2983573196343638 1.7668500877449687 1.4116463748812655 1.0709343674993552 1.1518178533594177 0.9504245340114632 1.1506978652676874 0.8192672966896357 1.058247037573127 1.0 15.511434761162475 -5.713482642883731 3.1761476653044 1.0223230490535888 1.5458493578295458 0.7044043534693676 0.13905895561766698 0.12003818315311995 2.45951192433168 0.03784696055690064 0.06810839951809951 1.9342711626145453e-06 5.713482642883731 0.523526308775957 DPAQPMS(ph)PGEATQSGAR ddPTM_PC-9_Lapatinib_30min_R1 4 DPAQPMSPGEATQSGAR 17 0 Q9BQG0;Q9BQG0-2 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 DPAQPMS(0.966)PGEAT(0.034)QSGAR;DPAQPMS(0.997)PGEAT(0.003)QSGAR;DPAQPMS(0.997)PGEAT(0.002)QSGAR;DPAQPMS(0.91)PGEAT(0.067)QS(0.024)GAR 180.76 1.7303e-06 93141000.0 23913.0 53033.0 49896.4 44472.8 58034.0 51023.0 54274.0 60066.0 53350.0 45118.2 True False 23571.99623489287 52910.20534683777 45794.11059767393 47743.47806891178 54620.55421923395 48840.86523042227 57084.042155278476 62856.88564171371 47341.1611995943 52916.82075377748 0.4454537498496672 0.9998749847998146 0.865397995294434 0.9022363284268851 1.0321964441776266 0.9229742931397812 1.078750411346349 1.1878431989364489 0.8946335120901012 1.0 15.691438766552654 -4.7607299164704 24.994126955438965 0.9887850386959441 0.4454531219024834 0.754811798109627 0.09260769425522591 8.841116930335872 311253.1824490356 0.024329510492661306 0.14144116362272643 1.7348825689999982e-05 4.7607299164704 -0.5433319167934607 DPAQPMS(ph)PGEATQSGARPADR ddPTM_PC-9_AZD4547_30min_R2 2 DPAQPMSPGEATQSGARPADR 21 1 Q9BQG0;Q9BQG0-2 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 DPAQPMS(0.993)PGEAT(0.004)QS(0.003)GARPADR;DPAQPMS(0.956)PGEAT(0.024)QS(0.02)GARPADR 63.691 0.0025047 17097000.0 19226.3 18836.0 29231.8 33801.0 28493.0 25078.0 21504.8 29086.0 20490.0 25500.7 True False 25339.863468116815 24924.368641944107 28844.167232281186 26008.701670244227 24537.238774980593 23509.868695595083 23418.685539682272 24591.427029787996 21573.059568835943 24607.928254809 1.0297438778969448 1.0128592859934589 1.1721493550211532 1.0569236630134224 0.9971273697201798 0.9553778136930593 0.9516723755526099 0.9993294346094421 0.8766711015024204 1.0 14.586835581745062 -6.396822363710111 2.7640770154768965 0.9569841972352474 1.072121249173231 0.5187555016140704 0.050599714856395424 0.22943017273576194 3.3942858502017703 0.017195954435847167 0.019802983095027187 4.0103071474067513e-07 6.396822363710111 0.11513705193798363 DPAQPMS(ph)PGEATQSGARPADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DPAQPMSPGEATQSGARPADR 21 1 Q9BQG0;Q9BQG0-2 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 DPAQPMS(0.99)PGEAT(0.009)QS(0.001)GARPADR;DPAQPMS(1)PGEATQSGARPADR 100.18 0.00044948 42978100.0 19748.1 15411.1 20704.0 23927.8 25771.9 24221.9 24212.3 25298.4 22534.7 16878.2 True False 23091.063287245895 16941.012159588285 21197.66188035725 22587.20294097427 20722.081200132132 22951.660923782034 21918.735662128143 24634.343805870496 22864.227356036045 19938.084052242317 1.158138526587713 0.849681048349429 1.0631744667549075 1.1328672745982342 1.0393215890672125 1.1511467633320964 1.099340117370158 1.2355421785424774 1.1467615090861571 1.0 14.283239160342045 -5.517854286963378 18.446487938530186 1.1206286702333155 0.9920393077799576 0.1864751914518703 0.09189087097142816 8.953363794233159 32864.22664202014 0.023600127714772046 0.042937605214702725 3.034909276033177e-06 5.517854286963378 -0.12858936245335784 DPAQPMS(ph)PGEATQSGARPADR ddPTM_PC-9_Lapatinib_30min_R1 4 DPAQPMSPGEATQSGARPADR 21 1 Q9BQG0;Q9BQG0-2 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 DPAQPMS(0.803)PGEAT(0.182)QS(0.015)GARPADR;DPAQPMS(0.985)PGEAT(0.011)QS(0.004)GARPADR;DPAQPMS(0.998)PGEAT(0.001)QS(0.001)GARPADR;DPAQPMS(0.818)PGEAT(0.104)QS(0.078)GARPADR 81.373 0.00036051 155472000.0 103369.2 81962.9 87304.0 76423.6 80735.5 84942.4 59155.3 66556.0 82411.1 68465.1 True False 101895.13625241027 81773.11994083553 80126.20212318563 82044.0464856561 75986.7966221002 81309.61156240558 62218.071984894144 69648.43473462357 73129.09409064442 80299.20131098882 1.2689433342902514 1.0183553336245326 0.9978455677643271 1.0217292967573826 0.9462957959919525 1.0125830672649354 0.7748280302805415 0.8673614880038949 0.9107076147298717 1.0 16.293098017722848 -1.5228787452803627 0.5247937300213229 0.903750846187183 13.549987791224352 0.6715527774899326 0.0699952151889891 72.84136997554573 0.720897945191432 0.037697402990294754 1027.4988706041363 0.029999999999998264 1.5228787452803627 12.646236945037169 DPAQPMSPGEAT(ph)QSGARPADR ddPTM_PC-9_Lapatinib_30min_R1 1 DPAQPMSPGEATQSGARPADR 21 1 Q9BQG0;Q9BQG0-2 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 DPAQPMS(0.026)PGEAT(0.487)QS(0.487)GARPADR 69.258 0.031996 6133900.0 15157.0 18717.0 16861.0 15956.0 15493.0 14611.0 17041.0 13358.0 14667.0 12497.0 True False 14940.858400546627 18673.661936469052 15474.753665342194 17129.45746765564 14581.73220040995 13986.121589904547 17923.299597746627 13978.661445776517 13015.048009642904 14657.089798794217 1.0193605010031224 1.2740361280999495 1.0557862357243144 1.1686806659985678 0.994858624773489 0.9542222761748469 1.2228416311689043 0.9537132976374675 0.887969452893275 1.0 13.839311060808726 -6.802670386940399 0.5167266415115044 0.960648619996828 1.1521090797125468 0.2276342901896513 0.10592295072195795 1.5010550645502798 0.858765543897014 0.09555260591593165 0.1190116049330772 1.575177911274197e-07 6.802670386940399 0.1914604597157188 DPEDRIPS(ph)PLGYAAIPIK ddPTM_PC-9_AZD4547_30min_R2 1 DPEDRIPSPLGYAAIPIK 18 1 Q9Y3A4 Q9Y3A4 RRP7A Ribosomal RNA-processing protein 7 homolog A 1 DPEDRIPS(0.995)PLGY(0.005)AAIPIK 65.416 0.034785 0.0 9058.1 10856.0 11077.0 10967.0 12724.0 11081.0 10633.0 12867.0 11327.0 11572.0 True False 11938.387379815615 14364.9896993494 10930.111742416777 8438.727588460953 10957.49223222732 10388.103318282532 11579.316401149592 10878.700804245418 11925.722095471185 11166.867802242676 1.0690900609943634 1.2863938172944465 0.9787983466788824 0.7556933365653508 0.9812502866763313 0.930261153104746 1.0369350301455242 0.9741944649922887 1.0679558768552904 1.0 13.446936960191366 -5.350062748962989 7.370186478826436 0.9581879891048124 1.176765204195338 0.4536527280163156 0.09295246027351325 0.2118660238564775 15.295547836796331 0.024609732327847314 0.051629133775733256 4.466190578117549e-06 5.350062748962989 0.21857721509052563 DPEDRIPS(ph)PLGYAAIPIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DPEDRIPSPLGYAAIPIK 18 1 Q9Y3A4 Q9Y3A4 RRP7A Ribosomal RNA-processing protein 7 homolog A 1 DPEDRIPS(0.991)PLGY(0.009)AAIPIK;DPEDRIPS(0.981)PLGY(0.019)AAIPIK 60.56100000000001 0.012190000000000001 3135900.0 14633.5 17747.1 17388.2 19228.5 20850.3 18714.0 17153.6 14801.3 15669.1 14061.0 True False 17110.66252520053 19508.91480150211 17802.800633115716 18151.189484638115 16764.833390130923 17732.60489588582 15528.68682669062 14412.781558273678 15898.230944475174 16610.14799318525 1.0301330567446256 1.1745178194382226 1.0718026498270687 1.0927771078310151 1.0093127043184167 1.0675765744628578 0.9348915393807252 0.8677094005536196 0.9571396324101292 1.0 14.019777307038979 -7.040838373939756 1.4543745161832102 0.9265282116033935 1.0905226099146819 0.5945748500834784 0.05293677014641753 0.25875442175829977 1.1037438244169997 0.027281302796878015 0.019458533382916775 9.102519669347659e-08 7.040838373939756 0.16399439831128837 DPEEIEKEEQAAAEK ddPTM_PC-9_Lapatinib_30min_R1 1 DPEEIEKEEQAAAEK 15 1 C9J9K3;A0A0C4DG17;P08865 C9J9K3 RPSA 40S ribosomal protein SA 0 129.77 1.8412e-05 1934000.0 13012.0 9875.4 9413.5 8384.6 9146.0 7238.5 9912.5 12710.0 7174.2 12673.0 False True 12826.446493891443 9852.534118042771 8639.558367160827 9001.23145420566 8608.050261727843 6928.926228767649 10425.720747764999 13300.553000136202 6366.166048324818 14863.511164288951 0.8629486231159326 0.6628672060821305 0.5812595874330297 0.6055925383116746 0.5791397582025929 0.46617021726434843 0.7014305457524612 0.8948459656081862 0.4283083571545436 1.0 13.859487339366163 -10.734352473674395 7.216385515090713 1.0000007297616105 0.6423233592773399 0.3625190520669791 0.14221861282779544 1.6666809606765773e-06 1.8221356986288492e-07 0.13744989650246897 0.03333642850931762 1.8435186109933734e-11 10.734352473674395 -0.3576773704842706 DPFAHLPK ddPTM_PC-9_AZD4547_30min_R2 1 DPFAHLPK 8 0 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 0 73.248 0.024419999999999997 0.0 50359.0 49364.0 66238.0 91184.0 71920.0 68494.0 67634.0 75038.0 63049.0 74930.0 False True 66372.11446772882 65319.94763436656 65359.6408408596 70162.93757875652 61935.14942956535 64211.05935226453 73653.294975581 63442.601301699586 66381.64142291537 72306.72350691681 0.9179245199981951 0.9033730815934164 0.9039220375489334 0.9703514994984497 0.8565614153936968 0.8880371871105754 1.0186230464243808 0.877409433379051 0.9180562775267413 1.0 16.14184218328313 -14.522878745197705 0.3242366305244017 1.8041456823550752 0.9138234537217281 0.2404164180561964 0.044243432318914505 508.6852509008796 4.462266064175057 281.2620507655715 0.038455098351175325 3.0000000005708066e-15 14.522878745197705 -0.8903222286333471 DPFAHLPK ddPTM_PC-9_Lapatinib_30min_R1 1 DPFAHLPK 8 0 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 0 64.265 0.046147 2431600.0 53733.0 72821.0 74236.0 81713.0 85348.0 75612.0 83670.0 69619.0 79596.0 71960.0 False True 52966.757566574604 72652.38744860902 68132.60263924695 87722.44660657705 80327.99844062397 72378.25102018083 88002.02319954585 72853.75289665477 70631.06029696162 84398.19011932737 0.6275816755274839 0.8608287375107049 0.8072756363959568 1.0393877698390173 0.9517739459466049 0.8575806059092973 1.0427003597485107 0.8632146352149216 0.8368788500926272 1.0 16.36492444087684 -4.233150939894649 1.1224578068939222 0.9319167312806188 1.2269019273140287e-16 0.5749427233101412 0.07787678234066776 3.569064238427042 1.5935448590470065 0.02369760188502078 5.2972120992582905 5.8458687452459706e-05 4.233150939894649 -0.9319167312806187 DPFS(ph)PDK ddPTM_PC-9_AZD4547_30min_R2 1 DPFSPDK 7 0 Q5PSV4;Q5PSV4-2;H0YHD0 Q5PSV4 BRMS1L Breast cancer metastasis-suppressor 1-like protein 1 DPFS(1)PDK 81.525 0.023815 3775800.0 35145.0 37394.0 31456.0 36981.0 31481.0 37702.0 35940.0 37506.0 33097.0 32499.0 True False 46320.378938587506 49480.87922047452 31038.87288701472 28455.60180075446 27110.406551614917 35344.48797995559 39138.59037499445 31710.30950213947 34846.43985113532 31361.219901925728 1.476995444802299 1.5777727835592312 0.9897214771645023 0.9073499656500017 0.8644563775387516 1.1270125361987362 1.2479932380625014 1.01113125067537 1.111131517208474 1.0 14.936694058652717 -5.261913497948273 24.999965643157626 1.0333690074296997 1.527384150682328 0.774920975707704 0.10671604031085148 19.3539467781382 1020590.8423552606 0.030836945965035122 0.07116706395777049 5.471249274739128e-06 5.261913497948273 0.4940151432526283 DPGGGAGAITVAS(ph)HSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DPGGGAGAITVASHSK 16 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 DPGGGAGAITVAS(0.786)HS(0.214)K 86.8 0.0024920000000000003 2771000.0 27061.0 24976.0 19303.0 29961.0 32479.0 18714.0 23215.0 19649.0 16929.0 18924.0 True False 31641.89282088712 27455.452219366358 19763.25672703516 28282.38230487257 26114.97310245234 17732.60489588582 21015.90713795489 19133.2345698364 17176.554598478542 22354.77139769843 1.415442468990976 1.2281696703994511 0.8840733092475246 1.265160882288621 1.168205777543359 0.7932357965293936 0.9401083448394653 0.8558904150460823 0.7683618988046096 1.0 14.448295172350464 -6.7514336781295095 24.51935153030869 0.8667992640451753 1.1811423332647697 0.5731730306281513 0.1381744462890746 126.41486840632848 309783.7412109266 0.04688017811304605 0.0463290505304403 1.772418693630012e-07 6.7514336781295095 0.31434306921959443 DPGGGAGAITVAS(ph)HSK ddPTM_PC-9_Lapatinib_30min_R1 2 DPGGGAGAITVASHSK 16 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 DPGGGAGAITVAS(0.758)HS(0.242)K;DPGGGAGAITVAS(0.971)HS(0.029)K 107.18 0.00053031 7696500.0 65533.0 68258.0 73986.0 59695.0 47733.0 56474.0 51347.0 45053.0 48639.0 38839.0 True False 64598.48740271968 68099.95279475904 67903.1566742192 64085.169436682365 44925.43878668873 54058.7386673239 54005.496417199465 47146.32685406269 43160.76362862355 45552.26940028554 1.4181178732297088 1.4949848534732313 1.4906646269920758 1.4068491050037706 0.9862393109750777 1.1867408447269376 1.18557202809441 1.0349940293812705 0.9474997447295787 1.0 15.475235309997856 -6.177869147899606 5.011637792428218 1.0718969708905115 1.4659189489919948 0.8610001554260271 0.07790428268163743 0.08512371590073428 3.7020226680279524 0.024782989987468182 0.032218655755028365 6.639430850555953e-07 6.177869147899606 0.3940219781014833 DPGLEPGPDS(ph)PGGSSPPR ddPTM_PC-9_AZD4547_30min_R2 1 DPGLEPGPDSPGGSSPPR 18 0 Q92508 Q92508 PIEZO1 Piezo-type mechanosensitive ion channel component 1 1 DPGLEPGPDS(0.972)PGGS(0.022)S(0.006)PPR 143.43 9.825200000000001e-09 0.0 1728.8 5942.6 6214.0 5904.2 6848.5 4352.3 5381.1 8166.4 6157.3 4814.7 True False 2278.5224387261374 7863.429236123227 6131.598299844527 4543.077908980681 5897.703988714933 4080.149992975457 5860.00747542801 6904.470525203219 6482.762307622917 4646.138818480624 0.4904120448711125 1.6924654090931186 1.3197191344036674 0.9778179444208588 1.2693774807709244 0.8781808190375474 1.2612639665692005 1.4860663434634769 1.395301036171559 1.0 12.181816544650747 -7.51438659387941 23.982819389759726 1.3391432796035672 1.1367809668649207 0.06228535983800754 0.3177306586844315 660.5257451226583 1865427.761437592 0.1382546902672214 0.08496291721075748 3.059238992861841e-08 7.51438659387941 -0.20236231273864647 DPGLEPGPDSPGGSS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 1 DPGLEPGPDSPGGSSPPR 18 0 Q92508 Q92508 PIEZO1 Piezo-type mechanosensitive ion channel component 1 1 DPGLEPGPDS(0.002)PGGS(0.209)S(0.79)PPR 164.82 1.515e-07 3058300.0 12804.0 20412.0 9054.3 5943.6 9023.2 4593.7 4734.0 5817.1 10843.0 3098.0 True False 12621.412612033973 20364.73726810955 8309.890404608728 6380.71217126837 8492.47311629375 4397.238159437719 4979.1033563601 6087.3837023676115 9621.747158148091 3633.4851721744803 3.473638122618405 5.604739335133203 2.2870302232816395 1.756085925472429 2.3372802457898514 1.2101984599007367 1.3703381520559026 1.675356693068485 2.6480766267693068 1.0 11.827138303527562 -5.398475476779438 5.179673634272014 1.7525271553555206 4.514113560327534 0.733851314326936 0.6693985898283541 0.1005577366228486 3.782613852709556 0.16888098598800938 0.36127074387991986 3.995071195608407e-06 5.398475476779438 2.761586404972013 DPGPT(ph)RT(ph)FTVVPRAAESTEIPPYVMK ddPTM_PC-9_AZD4547_30min_R2 1 DPGPTRTFTVVPRAAESTEIPPYVMK 26 2 H0YNS4;Q9BRN9 H0YNS4 TM2D3 TM2 domain-containing protein 3 2 DPGPT(0.995)RT(0.979)FT(0.022)VVPRAAES(0.002)T(0.002)EIPPY(0.001)VMK 42.903999999999996 0.036943000000000004 11488000.0 3636.4 2021.8 40968.0 32801.0 45032.0 15945.0 9164.7 50629.0 13088.0 14747.0 True False 4792.699558181242 2675.3073115461143 40424.73755198432 25239.236220398256 38780.084108901334 14947.956629366925 9980.34054562359 42805.45138867967 13779.804960318437 14230.712018637456 0.33678564726096727 0.18799532363822413 2.840668653756852 1.7735750809476944 2.725097947180186 1.0504011752743025 0.7013240470717624 3.007962731071987 0.9683145117596026 1.0 13.796720226941517 -5.23551095880213 24.62363008660483 1.8021569131936888 0.2623897507411143 0.35382125398013087 0.8069634343629669 655.558620494462 622566.2411146406 0.20040676000785496 0.5298003513361674 5.8141876084976955e-06 5.23551095880213 -1.5397671624525744 DPHLACVAYER ddPTM_PC-9_AZD4547_30min_R2 2 DPHLACVAYER 11 0 A0A087WVQ6;Q00610-2;Q00610;A0A087WX41;P53675-2;P53675 A0A087WVQ6 CLTC;CLTCL1 Clathrin heavy chain;Clathrin heavy chain 1;Clathrin heavy chain 2 0 ; 91.31299999999999 0.006932600000000001 4104800.0 13469.0 13700.2 18469.2 22139.9 18892.4 16084.599999999999 11144.400000000001 22015.0 15219.2 18253.1 False True 17751.861827396082 18128.52172798697 18224.286340439092 17035.888113045195 16269.516366561716 15078.827419298546 12136.230010436515 18613.08760437265 16023.655841387397 17614.064524811234 1.0078231405585432 1.029207182842499 1.034644009323816 0.9671752984127191 0.9236662181885628 0.8560674566655786 0.6890079228074462 1.0567173509642926 0.9097080244492359 1.0 14.104440235520359 -6.121990839017359 2.2830142724349947 0.8935185605229348 1.0238982470840923 0.25074840237567697 0.09084814934412266 0.42364671351974803 4.33748052945664 0.030376326245226584 0.04290707135613067 7.551081557051311e-07 6.121990839017359 0.1303796865611575 DPHLACVAYER ddPTM_PC-9_Lapatinib_30min_R1 3 DPHLACVAYER 11 0 A0A087WVQ6;Q00610-2;Q00610;A0A087WX41;P53675-2;P53675 A0A087WVQ6 CLTC;CLTCL1 Clathrin heavy chain;Clathrin heavy chain 1;Clathrin heavy chain 2 0 ;; 108.98 0.0015777999999999999 7092500.0 28090.6 30880.5 31190.0 25726.6 31134.0 24883.300000000003 22465.6 26492.9 31337.4 24465.9 False True 27690.022892814846 30808.998099542267 28625.678596881746 27618.619985421763 29302.759331799105 23819.09926480542 23628.758842974974 27723.856851086428 27807.852014548564 28694.79821623744 0.9649840603216362 1.07367885521873 0.9975912143087808 0.9624957031338627 1.0211871542354196 0.8300842224193435 0.8234509497126987 0.966163157592738 0.9690903488846636 1.0 14.80850160886116 -6.733452112789863 24.998991325858768 0.9097487166388922 1.0051987440563985 0.32992907580967856 0.06089898901553237 246.97957140438263 220608.33873628156 0.02102163981710955 0.021017612118476588 1.8473444799665155e-07 6.733452112789863 0.0954500274175063 DPHLLDPTVEY(ph)VK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DPHLLDPTVEYVK 13 0 O75815 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 DPHLLDPT(0.003)VEY(0.997)VK 103.97 0.010546999999999999 0.0 10624.0 15885.0 15782.0 12543.0 14808.0 12260.0 15776.0 10319.0 12108.0 9437.1 True False 12422.433366435276 17461.957819692285 16158.302733568298 11840.256374954663 11906.478700117432 11617.06401750348 14281.583071650928 10048.137183884264 12285.056593914478 11147.971525957504 1.1143223085482636 1.56637983681901 1.4494388235513953 1.0620996247958838 1.0680399274786252 1.0420787306868984 1.2810925322509985 0.9013422002816989 1.1019992798967353 1.0 13.444493602190608 -5.766432576808613 24.998540694745095 1.0692712217605678 1.395680300979595 0.5147714379543747 0.13817420050296053 89.08322313537175 445999.5675261817 0.03748448033682976 0.057611230874428286 1.712250978985452e-06 5.766432576808613 0.3264090792190273 DPHLLDPTVEY(ph)VK ddPTM_PC-9_Lapatinib_30min_R1 1 DPHLLDPTVEYVK 13 0 O75815 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 DPHLLDPTVEY(1)VK 99.844 0.022565 0.0 14417.0 22841.0 19345.0 15457.0 20958.0 20297.0 18773.0 20574.0 20506.0 16575.0 True False 14211.410936245999 22788.113067846858 17754.528773859467 16593.759343040434 19725.291645013334 19428.944624617932 19744.97408300554 21529.94314907964 18196.398342247045 19439.966665200784 0.7310409107689289 1.1722300485545352 0.9133003713242782 0.8535899072679324 1.0146772360635425 0.9994330216315349 1.0156897088898176 1.107509262740666 0.9360303263698577 1.0 14.246738124625306 -6.4618503678998005 23.986818312493405 1.0174054048830912 0.9352674244558428 0.14310815047739955 0.10971920034610884 349.2032069819614 137251.2399823133 0.032982694646251774 0.037398794257246126 3.452626758699146e-07 6.4618503678998005 -0.0821379804272484 DPIWRS(ph)REEPYHYGNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DPIWRSREEPYHYGNK 16 2 A0A1X7SBR1;Q7Z3G6 A0A1X7SBR1 PRICKLE2 Prickle-like protein 2 1 DPIWRS(1)REEPYHYGNK 50.102 0.030742000000000002 33969000.0 59199.0 60652.0 57640.0 75709.0 81456.0 66066.0 63193.0 63891.0 59461.0 61716.0 True False 69220.22146645341 66673.12972489625 59014.356200917304 71467.27018188986 65495.281536788665 62601.382657453934 57206.90156229951 62213.92894811016 60330.50463583979 72904.62225641283 0.9494627271093867 0.9145254122626163 0.8094734514000762 0.9802844863598956 0.898369397024447 0.8586750842392219 0.7846814069085651 0.8533605555117969 0.8275264690852027 1.0 16.15372266591241 -6.749209216812102 4.591982608452603 0.8501261381390145 0.9096014315893224 0.08793330429547042 0.06630763379986745 0.37862008037576106 19.63896831278388 0.022345173713126897 0.021148364558634763 1.7815203319568725e-07 6.749209216812102 0.05947529345030789 DPLQNS(ph)PGSEGK ddPTM_PC-9_AZD4547_30min_R2 1 DPLQNSPGSEGK 12 0 Q6IE81-2;Q6IE81 Q6IE81-2 JADE1 Protein Jade-1 1 DPLQNS(0.982)PGS(0.018)EGK 176.56 0.0009756999999999999 6753900.0 23889.0 20167.0 30779.0 39048.0 38082.0 33590.0 31486.0 29865.0 31792.0 29677.0 True False 31485.205077931936 26685.588362820476 30370.850349358647 30046.086885586123 32794.97164316888 31489.611989992794 34288.19300353576 25250.050479427184 33472.46021534563 28638.01726297579 1.099419865167729 0.9318238800463507 1.0605081375037482 1.0491678460027585 1.1451551042106305 1.099573748448837 1.1972963312604992 0.8816968803238803 1.1688120692147208 1.0 14.805643991429134 -4.443857779224409 22.87162513497706 1.0607865836379258 3.578558572887291 0.015363096909174812 0.09563550085900632 4675.089186425907 1244320.3200456565 0.022383185897028708 49091.03049202196 3.598671635186615e-05 4.443857779224409 2.5177719892493653 DPLQNS(ph)PGSEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DPLQNSPGSEGK 12 0 Q6IE81-2;Q6IE81 Q6IE81-2 JADE1 Protein Jade-1 1 DPLQNS(0.786)PGS(0.214)EGK 124.81 0.00031141 6052200.0 21545.0 27973.0 26795.0 30656.0 27689.0 30014.0 31907.0 28898.0 29528.0 18033.0 True False 25192.142966853156 30749.974572883377 27433.89442060338 28938.443708092975 22263.539217149628 28440.013003372736 28884.53797332441 28139.458119961942 29959.79113851229 21302.24015085053 1.182605340492667 1.4435089622091049 1.2878408198542457 1.3584695085196263 1.0451266655286822 1.3350714667554442 1.3559389889880262 1.3209623927199234 1.406415049607639 1.0 14.378717532281572 -10.483568704787894 4.285720815003548 0.9999898624672722 1.3045510699618872 0.41161383001232354 0.10903454672550067 6897537.511569945 4218123.9321753215 620.4115895931999 0.026136749075264854 3.284212843990746e-11 10.483568704787894 0.304561207494615 DPLQNS(ph)PGSEGK ddPTM_PC-9_Lapatinib_30min_R1 1 DPLQNSPGSEGK 12 0 Q6IE81-2;Q6IE81 Q6IE81-2 JADE1 Protein Jade-1 1 DPLQNS(0.67)PGS(0.33)EGK 94.781 0.0048016000000000005 6153400.0 22816.0 18058.0 20658.0 17813.0 18052.0 19559.0 18872.0 20522.0 20064.0 14558.0 True False 22490.63965605805 18016.187810480205 18959.578982186056 19123.027442426057 16990.216851597525 18722.507164255898 19849.099818594812 21475.527039244313 17804.181036713402 17074.330902684345 1.3172193853009009 1.055162156172561 1.1104141702680321 1.1199869295856053 0.9950736546242291 1.0965294787224977 1.1625111362621086 1.2577668291451487 1.042745460316358 1.0 14.059541423816338 -4.75371768951837 24.854457526763746 1.1019641118530805 1.3172198028530009 0.4429394751469782 0.07475675655323395 264.9739198494619 852819.34780366 0.019067612709546683 0.19865479711575187 1.7631217805525715e-05 4.75371768951837 0.21525569099992037 DPLQNSPGS(ph)EGK ddPTM_PC-9_Lapatinib_30min_R1 1 DPLQNSPGSEGK 12 0 Q6IE81-2;Q6IE81 Q6IE81-2 JADE1 Protein Jade-1 1 DPLQNS(0.346)PGS(0.654)EGK 85.271 0.009756200000000001 7298800.0 29128.0 21289.0 30551.0 20953.0 30671.0 29891.0 24732.0 26152.0 25034.0 24287.0 True False 28712.62937857902 21239.70662849225 28039.214710270408 22493.953517158978 28866.992081506076 28612.631609324268 26012.501945394593 27367.117392569817 22214.40730029322 28484.97558960671 1.0079920654401182 0.7456459480429383 0.9843510176817933 0.7896778231878256 1.0134111574256974 1.0044815211203528 0.9132007806559523 0.9607562171320672 0.7798640104293637 1.0 14.797913549431232 -4.462632415011152 23.171847793145137 0.9115788703234085 3.407692972425706 0.08356496231701838 0.0970969851050622 1189.315710487184 563625.881240766 0.022402840432677647 35350.44965061127 3.4464151044793955e-05 4.462632415011152 2.4961141021022977 DPNGAS(ph)PTSQQPLVR ddPTM_PC-9_Lapatinib_30min_R1 1 DPNGASPTSQQPLVR 15 0 J3KQ26;Q96C12-3;Q96C12-4;Q96C12-2;Q96C12 J3KQ26 ARMC5 Armadillo repeat-containing protein 5 1 DPNGAS(0.447)PT(0.447)S(0.107)QQPLVR 96.773 0.0025793 2316200.0 10730.0 14486.0 14440.0 13013.0 13881.0 15031.0 8915.3 8277.0 16653.0 5591.6 True False 10576.988232358988 14452.458557017186 13252.798940011939 13970.01943009544 13064.546871096018 14388.159168972374 9376.89061110207 8661.57963667407 14777.363776135777 6558.100609661334 1.612812742881234 2.2037567608715785 2.0208288540874224 2.130192911269909 1.9921235810029274 2.193952186060682 1.4298180478183151 1.3207451596448385 2.253299340111663 1.0 12.679062319352207 -7.265524412740572 24.90432294079829 1.5276943816695443 2.036722876714412 0.3737930380676777 0.33176366460209883 369.8800345628845 2254952.101487949 0.12857912134340618 0.09028967481500655 5.4259474991183054e-08 7.265524412740572 0.5090284950448676 DPNS(ph)PLYSVK ddPTM_PC-9_AZD4547_30min_R2 1 DPNSPLYSVK 10 0 I3L0H8;F6QDS0;H3BQK0;Q9UMR2-2;Q9UMR2-4;Q9NUU7;Q9UMR2;H3BTB3;H3BMQ5;H3BN59 I3L0H8 DDX19A;DDX19B ATP-dependent RNA helicase DDX19B;ATP-dependent RNA helicase DDX19A 1 DPNS(0.905)PLY(0.059)S(0.037)VK 71.806 0.032208999999999995 3653200.0 25037.0 26862.0 34240.0 26526.0 24841.0 28580.0 22729.0 34716.0 24573.0 26058.0 True False 32998.245198048535 35544.61618495977 33785.95522798145 20410.840522614664 21392.255936871967 26792.888081988487 24751.83696809264 29351.439894317566 25871.878613226214 25145.71735143792 1.3122809238990185 1.4135455230084022 1.3436067365184732 0.8117024556250132 0.850731583350462 1.0655050204983068 0.984336084835426 1.167254029149387 1.0288781286944184 1.0 14.618025090436815 -5.712304230620488 10.795534782146724 0.9914567265754642 1.3629233762958324 0.7500060420835781 0.09773172163900935 0.28893127996139256 61.9406425665085 0.029116566537988664 0.05037945934238299 1.9395267303592982e-06 5.712304230620488 0.37146664972036814 DPNSATATAPPS(ph)PLKR ddPTM_PC-9_AZD4547_30min_R2 1 DPNSATATAPPSPLKR 16 1 Q92766;Q92766-2;Q92766-5;Q92766-3;C9JU34;Q92766-6 Q92766 RREB1 Ras-responsive element-binding protein 1 1 DPNSATATAPPS(1)PLKR 52.318000000000005 0.037719 6618500.0 14638.0 18954.0 21754.0 23869.0 21270.0 21823.0 18125.0 24673.0 18805.0 22239.0 True False 19292.579510685573 25080.509834328335 21465.52774618892 18366.370822373887 18317.027646925097 20458.404360155186 19738.089887222446 20860.354779136338 19798.993908831617 21460.419379024777 0.8989842728582447 1.1686868458331157 1.0002380366885624 0.855825345161941 0.8535260808942063 0.9533086934988347 0.9197439033514079 0.9720385427101701 0.9225818731288624 1.0 14.389390649032862 -5.535036681360232 18.535960928580682 0.922528300859771 1.0464920587141673 0.26828703805489806 0.07437003436920182 10.508707719192538 16020.83633740695 0.01939318908057028 0.033707950260798585 2.9171806128229765e-06 5.535036681360232 0.12396375785439628 DPNSATATAPPS(ph)PLKR ddPTM_PC-9_Lapatinib_30min_R1 2 DPNSATATAPPSPLKR 16 1 Q92766;Q92766-2;Q92766-5;Q92766-3;C9JU34;Q92766-6 Q92766 RREB1 Ras-responsive element-binding protein 1 1 DPNSATAT(0.001)APPS(0.998)PLKR;DPNSATATAPPS(1)PLKR 67.655 0.011276999999999999 11105700.0 33035.0 38430.0 34372.0 47059.0 49196.0 49796.0 52854.0 53244.0 50577.0 44267.0 True False 32563.914842122955 38341.01769613214 31546.066839756924 50519.87584422206 46302.38800305736 47666.34116014556 55590.521503391785 55717.91061677831 44880.485660578815 51918.49196793016 0.6272122630649124 0.7384848103796087 0.6076075333475172 0.9730613107065587 0.8918284458581376 0.9180994931360653 1.070726814209662 1.0731804508342622 0.8644412416350865 1.0 15.66396085876506 -5.7680043950709345 24.997324772368103 0.9719937290114824 0.6658398475105755 0.797999004496376 0.07199407996685397 65.93724068506833 251067.32850945776 0.020984030025822987 0.031961150442472684 1.7060651234943717e-06 5.7680043950709345 -0.30615388150090694 DPNSPLYS(ph)VK ddPTM_PC-9_AZD4547_30min_R2 1 DPNSPLYSVK 10 0 I3L0H8;F6QDS0;H3BQK0;Q9UMR2-2;Q9UMR2-4;Q9NUU7;Q9UMR2;H3BTB3;H3BMQ5;H3BN59 I3L0H8 DDX19A;DDX19B ATP-dependent RNA helicase DDX19B;ATP-dependent RNA helicase DDX19A 1 DPNS(0.22)PLY(0.004)S(0.776)VK 74.69800000000001 0.025521000000000002 5086000.0 28706.0 28985.0 30769.0 29650.0 33971.0 30867.0 31507.0 39305.0 28875.0 31090.0 True False 37833.91087810767 38353.83441743203 30360.982955892538 22814.650587933545 29254.71303214351 28936.881610452718 34311.06196285337 33231.31538904686 30401.27355051917 30001.548563059514 1.2610652679672687 1.2783951580638264 1.011980528007664 0.7604490994849814 0.9751067672608216 0.9645129333784555 1.1436430319833588 1.1076533372668673 1.0133234785071006 1.0 14.872749348490192 -5.27329096977205 7.117006736002711 0.9953940356698019 1.270588304908915 0.5643706081206904 0.09583450804973939 0.10723517050957536 34.28089384579169 0.02810339796819433 0.06357325666667757 5.3297769002996e-06 5.27329096977205 0.27519426923911317 DPPQECSTFSPTDSGEEPGQLS(ph)PGVQFQR ddPTM_PC-9_AZD4547_30min_R2 1 DPPQECSTFSPTDSGEEPGQLSPGVQFQR 29 0 Q07002;Q07002-3;A0A0A0MSJ6 Q07002 CDK18 Cyclin-dependent kinase 18 1 DPPQECSTFSPTDSGEEPGQLS(1)PGVQFQR 89.89299999999999 1.4662999999999999e-08 3483500.0 4141.6 3283.8 2749.6 4546.8 4373.4 4162.0 5050.8 4583.9 5217.1 5284.5 True False 5458.542649368447 4345.224131791041 2713.1385074432746 3498.605507359736 3766.228900379041 3901.749482058648 5500.311415303898 3875.563582542982 5492.865255079256 5099.491263476613 1.0704092560101863 0.8520897295995473 0.5320410149293154 0.6860695168589303 0.7385499270002452 0.7651252410222983 1.0786000271631062 0.7599902386931024 1.0771398500905476 1.0 12.316137612477885 -7.232124521314104 21.727894446868337 0.9589316018937366 0.760981850147932 0.2970955704530883 0.15236472590706618 193.74857290799852 143604.10411940643 0.060346249776548996 0.04672638047098846 5.859701305298861e-08 7.232124521314104 -0.19794975174580465 DPPQECSTFSPTDSGEEPGQLS(ph)PGVQFQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DPPQECSTFSPTDSGEEPGQLSPGVQFQR 29 0 Q07002;Q07002-3;A0A0A0MSJ6 Q07002 CDK18 Cyclin-dependent kinase 18 1 DPPQECSTFSPTDSGEEPGQLS(1)PGVQFQR;DPPQECSTFSPTDS(0.042)GEEPGQLS(0.958)PGVQFQR 117.22 1.5719e-13 7192600.0 5102.2 7361.9 10694.8 9501.3 10216.9 7443.5 5191.7 7176.299999999999 7010.799999999999 7040.299999999999 True False 5965.901686956515 8092.7407788978735 10949.804592254863 8968.972964630208 8214.971787630324 7053.149756467143 4699.904591346986 6987.929728918365 7113.319686869471 8316.650659015866 0.7173442689322336 0.9730769165018062 1.3166123047845544 1.0784356987397536 0.9877740600688434 0.8480757513628404 0.5651198762631614 0.8402336487878003 0.8553106266593157 1.0 13.02178691753544 -6.761693328350763 3.56770623983872 0.7911302465930486 1.0371340782411647 0.23796710058440163 0.1699242786762139 0.30381686377384315 8.231192499686241 0.06390336851295239 0.05959671856925312 1.73103827890297e-07 6.761693328350763 0.246003831648116 DPPQECSTFSPTDSGEEPGQLS(ph)PGVQFQR ddPTM_PC-9_Lapatinib_30min_R1 1 DPPQECSTFSPTDSGEEPGQLSPGVQFQR 29 0 Q07002;Q07002-3;A0A0A0MSJ6 Q07002 CDK18 Cyclin-dependent kinase 18 1 DPPQECST(0.001)FS(0.008)PT(0.063)DS(0.13)GEEPGQLS(0.799)PGVQFQR 59.673 0.00076466 3794500.0 1316.3 1075.3 3577.6 1508.9 3839.4 3714.4 4303.6 1168.0 3451.9 1597.0 True False 1297.5293206201432 1072.8102089162355 3283.4635379353645 1619.8695395428438 3613.574040550826 3555.5437706893063 4526.419350323477 1222.2695439936347 3063.110671881527 1873.0393221312604 0.6927400323575341 0.5727643815269855 1.7530136709565904 0.8648347743707033 1.9292569023265764 1.8982750274797155 2.4166173645372466 0.6525594682138657 1.6353691220940998 1.0 10.871165472149226 -5.255547964374366 24.470062407612037 1.543261524122776 0.6327520599629602 0.32102594196121503 0.5144123400679652 405.5424658265273 1684407.5820610677 0.13300250827705482 0.33221463045343747 5.552032959413435e-06 5.255547964374366 -0.9105094641598158 DPQT(ph)PVLQTK ddPTM_PC-9_AZD4547_30min_R2 2 DPQTPVLQTK 10 0 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 DPQT(0.997)PVLQT(0.003)K;DPQT(0.99)PVLQT(0.01)K 101.72 0.008541799999999999 28511000.0 155449.0 197083.0 179230.0 155444.0 178961.0 210360.0 161663.0 243620.0 201861.0 198303.0 True False 204878.5484599371 260786.2255818786 176853.2930931983 119608.78738585977 154115.3542417191 197206.1559456646 176050.6938172717 205974.12683067264 212530.96035260087 191360.47232873534 1.0706419458872325 1.3628009087157653 0.9241892588422578 0.6250443779234909 0.8053667111406717 1.0305480204233977 0.9199950840152443 1.076367153174835 1.1106314578252976 1.0 17.545933330046395 -5.28104035367231 24.09940686903282 0.9262052381607444 1.2167214048215693 0.3609381451641315 0.14863229920938503 491.5595477841529 604372.5115118836 0.04218227056089849 0.08804587492633151 5.23551787064029e-06 5.28104035367231 0.2905161666608249 DPQT(ph)PVLQTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DPQTPVLQTK 10 0 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 DPQT(1)PVLQTK;DPQT(0.979)PVLQT(0.021)K;DPQT(0.988)PVLQT(0.012)K 117.27 0.0023742 15780300.0 135419.0 192290.0 159807.0 115364.0 175731.0 104613.0 135740.0 89206.0 91011.0 86159.0 True False 158342.76205283293 211379.28039966233 163617.40495142253 108900.52909513413 141297.77204553876 99126.91011933867 122881.72452750344 86864.43702156968 92341.86369910404 101778.94466573135 1.5557516593719058 2.076846847782585 1.6075761591828726 1.06997109719296 1.3882809701908145 0.973943190754211 1.2073393463754132 0.8534617578012347 0.9072786518113235 1.0 16.635079611801785 -5.672655712708533 3.354879589805496 1.0630159636128156 1.8254228647456208 0.7461599401134271 0.1864703921140759 0.11327729301158403 2.5085020520140917 0.05266488606611306 0.09657268244349335 2.1249283330711715e-06 5.672655712708533 0.7624069011328052 DPQT(ph)PVLQTK ddPTM_PC-9_Lapatinib_30min_R1 1 DPQTPVLQTK 10 0 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 DPQT(0.992)PVLQT(0.008)K 139.76 0.00029764 13821000.0 55507.0 89726.0 88216.0 87545.0 94175.0 76109.0 79802.0 71953.0 75502.0 59036.0 True False 54715.460001262865 89518.24495974892 80963.22100360758 93983.35134155891 88635.81165517378 72853.9954887445 83933.75708581517 75296.19905734083 66998.16968869299 69240.29393947459 0.7902257036790109 1.2928634450627838 1.1693078754746538 1.357350554053296 1.2801189395968409 1.0521907309121012 1.2122097164865397 1.087462152069428 0.9676182158795927 1.0 16.079324228808048 -8.030075777967939 3.2306695529266087 0.9859868316069643 1.1773948669682806 0.18425116691236632 0.14972462314011284 0.4089757127130065 8.402327181772606 0.11039767931478768 0.03961410640861978 9.330914759212838e-09 8.030075777967939 0.19140803536131623 DPS(ph)ASPGDAGEQAIR ddPTM_PC-9_AZD4547_30min_R2 1 DPSASPGDAGEQAIR 15 0 P18206;P18206-2 P18206 VCL Vinculin 1 DPS(0.984)AS(0.016)PGDAGEQAIR 155.37 0.00019182 9267800.0 6199.5 7955.5 8077.9 8744.8 8566.4 7801.5 9921.5 12430.0 6734.3 7820.8 True False 8170.812042389341 10526.959796718325 7970.781767993898 6728.821465813195 7377.103226827418 7313.670971715654 10804.494279507724 10509.229112984425 7090.261349654068 7546.99617246625 1.0826575044782667 1.3948542646839936 1.056152883325123 0.8915893571487413 0.9774886667812748 0.9690836996046404 1.4316284297222548 1.392504895036956 0.9394812436133875 1.0 12.881686827193132 -7.230860004362883 24.987261397020273 1.2236125304647336 1.0652529306197007 0.09018582135464459 0.18938356463773134 1470.8450314949855 1201870.3933384637 0.07616182792478982 0.05898783956641666 5.8767876134597414e-08 7.230860004362883 -0.1583595998450329 DPS(ph)ASPGDAGEQAIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DPSASPGDAGEQAIR 15 0 P18206;P18206-2 P18206 VCL Vinculin 1 DPS(0.996)AS(0.004)PGDAGEQAIR 116.87 0.0019884 0.0 6668.3 14518.0 7877.1 7802.1 9192.8 9530.0 12240.0 6920.8 7245.2 6144.2 True False 7797.1114850715685 15959.251093880557 8064.919938068106 7364.973631749484 7391.536831066957 9030.23002339382 11080.538590073998 6739.136333193734 7351.147343428238 7258.094822539561 1.074264207854949 2.198820969425764 1.111162107309896 1.0147254633375713 1.0183852666285098 1.2441598303939214 1.5266456089363942 0.9284993511335462 1.0128205160119579 1.0 12.825375189524799 -5.398057531810148 22.331447936779224 1.1178555983176992 1.6412648667623606 0.33293486713177445 0.2994638208429472 7.054044990868674 1237.9437150142157 0.07470652424102547 0.15551408483355414 3.998917718339539e-06 5.398057531810148 0.5234092684446614 DPS(ph)ASPGDAGEQAIR ddPTM_PC-9_Lapatinib_30min_R1 1 DPSASPGDAGEQAIR 15 0 P18206;P18206-2 P18206 VCL Vinculin 1 DPS(0.898)AS(0.102)PGDAGEQAIR 172.09 0.00010815 11722000.0 6926.2 11447.0 13766.0 12395.0 11849.0 12207.0 12866.0 13146.0 11250.0 10712.0 True False 6827.431117890481 11420.495174801583 12634.212618296697 13306.56964850788 11152.065116030302 11684.935065906839 13532.138526178514 13756.811151832457 9982.906532248084 12563.554927157213 0.5434314696338373 0.9090178091326041 1.0056240205538285 1.059140484174951 0.887652036441067 0.9300659832074152 1.0770947080374222 1.0949775944462914 0.7945925010976922 1.0 13.616957120062304 -4.758797732532987 3.132819933265509 0.984899841254524 0.46292047119769175 0.692988088097557 0.08693236449295105 0.21571586294325448 3.0339437079412015 0.02210463501549448 0.289488792126885 1.742618288074549e-05 4.758797732532987 -0.5219793700568323 DPS(ph)PESNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DPSPESNK 8 0 Q8NDX5-2;Q8NDX5;Q8NDX5-7;E7EX82;Q8NDX5-3 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 1 DPS(0.5)PES(0.5)NK 74.84100000000001 0.027214999999999996 5168800.0 20568.0 44281.0 30632.0 20875.0 68442.0 38264.0 33005.0 28922.0 33687.0 46392.0 True False 24049.756163482743 48676.92503706604 31362.383052506924 19705.44142766313 55031.28141500791 36257.36848007778 29878.52746449283 28162.82814539203 34179.60864545731 54802.50236113004 0.4388441243978778 0.8882244959600839 0.5722801277547397 0.35957192789867337 1.0041746096258577 0.6616006006651654 0.54520370744393 0.5138967552942834 0.6236870064842148 1.0 15.741954149771189 -10.942045032319767 2.580392730004453 1.0117620648511565 0.6284529941784044 0.27219547288964097 0.18472329754629777 6088741.55885324 6233826.392251541 524432.3818839306 0.048020655664376515 1.1427598350239093e-11 10.942045032319767 -0.3833090706727521 DPS(ph)PESNK ddPTM_PC-9_Lapatinib_30min_R1 2 DPSPESNK 8 0 Q8NDX5-2;Q8NDX5;Q8NDX5-7;E7EX82;Q8NDX5-3 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 1 DPS(0.977)PES(0.023)NK;DPS(0.83)PES(0.17)NK 93.556 0.0071363 13601800.0 32633.6 111827.0 72832.0 76778.0 126370.0 79018.0 186739.0 170791.0 99745.0 112826.0 True False 32168.238879730703 111568.07145213052 66844.03409965012 82424.51024389974 118937.16505297917 75638.58433995472 196407.43169905568 178726.57336319904 88510.66773858535 132327.82376880475 0.24309504957878794 0.8431187657635447 0.5051396765689732 0.6228811741656608 0.8988069301342025 0.5716000020683928 1.4842489365064069 1.3506348723414314 0.6688742036083499 1.0 17.013756914684187 -7.241676473095413 24.895851498255784 1.1551590869365347 0.6329032088596261 0.4730935307843004 0.2634551484836476 665.2990847161203 838095.6913777936 0.09922044102613856 0.07674827088460033 5.732228933493774e-08 7.241676473095413 -0.5222558780769085 DPSASNGGGS(ph)PARR ddPTM_PC-9_AZD4547_30min_R2 2 DPSASNGGGSPARR 14 1 O60504-2;O60504;E5RIA0;E5RJP2 O60504-2 SORBS3 Vinexin 1 DPSAS(0.002)NGGGS(0.998)PARR;DPS(0.003)AS(0.003)NGGGS(0.994)PARR 97.223 0.004047 3825100.0 4584.3 6950.2 8773.0 9526.5 10452.3 9286.8 9557.9 10900.8 8483.2 8228.9 True False 6042.012040636418 9196.716231431294 8656.664287823629 7330.312607957806 9001.178564830996 8706.094927915006 10408.534583894256 9216.331835464243 8931.604633203959 7940.808715682225 0.7608811969874186 1.1581586411052553 1.0901489505379556 0.923119152018011 1.1335342390321854 1.0963738379343435 1.3107650563775126 1.1606288686016326 1.1247726715246296 1.0 12.955070227885557 -6.395497895141082 5.940009244536296 1.1546790551980053 1.003648443960643 0.26636070714769133 0.1222703436106399 0.33407081747594697 14.768365668535797 0.03782312976045342 0.04286678727952964 4.0225560557272116e-07 6.395497895141082 -0.15103061123736228 DPSASNGGGS(ph)PARR ddPTM_PC-9_Lapatinib_30min_R1 2 DPSASNGGGSPARR 14 1 O60504-2;O60504;E5RIA0;E5RJP2 O60504-2 SORBS3 Vinexin 1 DPSASNGGGS(1)PARR;DPSASNGGGS(1)PARR 103.67 0.00053006 18004700.0 27280.0 36977.0 34137.0 31739.0 30798.0 32003.0 26795.3 23473.3 33205.0 16917.8 True False 26890.9821974607 36891.38202836011 31330.387632630715 34073.1919382002 28986.52219119768 30634.30629263672 28182.629523590163 24563.955211494675 29465.103235848692 19842.019188448485 1.355254318729615 1.8592554355474733 1.578991902742966 1.7172240191178094 1.4608655457844175 1.5439107281214217 1.4203508854581377 1.2379765878764586 1.4849851195085286 1.0 14.27627122608746 -8.466970579949816 0.3471824771515148 0.9579377203428984 1.6757613266599118 0.5849540820075547 0.14697814343197949 1.0429919008893127 0.3633600193250896 0.2681497453403536 0.1554651372827444 3.412160255526904e-09 8.466970579949816 0.7178236063170135 DPVQEAWAEDVDLR ddPTM_PC-9_AZD4547_30min_R2 2 DPVQEAWAEDVDLR 14 0 P14618;P14618-2;P14618-3;B4DNK4;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ; 231.69 1.3643e-20 22172100.0 12139.599999999999 9914.8 13109.1 14008.5 12797.8 14433.3 14577.400000000001 17617.0 15653.099999999999 12989.5 False True 15999.740280633865 13119.565205518553 12935.264768666219 10779.056754167525 11021.046376108041 13530.78346934096 15874.760359834281 14894.697448386683 16480.49090956299 12534.741558696094 1.2764316045697723 1.0466562189642221 1.0319530488997004 0.8599345031321729 0.8792400165970783 1.0794625007608436 1.2664609226682475 1.188273198824219 1.3147850581833092 1.0 13.613644630541309 -7.0614312220334625 5.557058084961658 1.205588288993166 1.0091360429192402 0.27799828271389837 0.1307288874136852 0.2698322345654084 16.98909996181083 0.05194921250804658 0.04060706236929354 8.680980445945529e-08 7.0614312220334625 -0.19645224607392575 DPVQEAWAEDVDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DPVQEAWAEDVDLR 14 0 P14618;P14618-2;P14618-3;B4DNK4;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ;; 173.06 0.00063512 14392600.0 16326.0 18396.6 16632.6 15360.9 17168.0 13324.8 16220.0 11529.0 12027.1 10127.2 False True 19089.669346801787 20222.892869106145 17029.184263486768 14500.278573709733 13804.05364151919 12626.024031030216 14683.52417736929 11226.37596598523 12202.973584462245 11963.181193128912 1.595701765159755 1.6904277000101964 1.4234662159315559 1.2120754788900139 1.1538781715893083 1.0554069045014556 1.2273929434256847 0.9384105937000379 1.0200441995705172 1.0 13.546313454811976 -5.693245954076595 1.146818065368017 1.0533984621542622 1.6915133381128096 0.8973994644355715 0.07857430426359718 0.1651845388952882 0.41156444182199875 0.028526020040237302 0.0866908771255999 2.026534706688657e-06 5.693245954076595 0.6381148759585473 DPVQEAWAEDVDLR ddPTM_PC-9_Lapatinib_30min_R1 2 DPVQEAWAEDVDLR 14 0 P14618;P14618-2;P14618-3;B4DNK4;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ; 220.32 3.6746e-15 32003000.0 11215.400000000001 15167.0 10936.9 12902.5 14023.7 10257.3 12903.0 13355.6 12454.2 10223.2 False True 11055.46633934754 15131.881743357697 10037.710299654878 13851.392891478243 13198.85353765501 9818.619189934147 13571.05420513612 13976.14993301489 11051.47684745993 11990.26649844226 0.9220367487898482 1.2620137963842242 0.8371548956780024 1.1552197687414014 1.1007973458613087 0.8188824819873479 1.1318392470175063 1.165624628512688 0.9217040212488775 1.0 13.549576104332303 -3.1847210815438247 7.182085712771762 1.0393717447576365 1.0441754309799856 0.0 0.14488750107712678 0.0 0.0 0.03117556098525964 0.0 0.0006535501496799776 3.1847210815438247 0.004803686222349057 DPYGS(ph)LDR ddPTM_PC-9_AZD4547_30min_R2 2 DPYGSLDR 8 0 A1BQX2;A0A0G2JQ38;D6RA09;A0A0G2JN23;Q8N4S9-2;Q8N4S9-3;Q8N4S9 A1BQX2 MARVELD2 MARVEL domain-containing protein 2 1 DPY(0.14)GS(0.86)LDR;DPYGS(1)LDR 82.831 0.015913999999999998 12557300.0 57963.0 92357.0 83353.0 107631.0 84290.0 69077.0 86349.0 106067.0 87942.0 74333.0 True False 76394.02829470325 122209.59411042859 82247.68475811736 82818.3358323736 72587.78845130786 64757.60427010219 94033.893719822 89676.78232718594 92590.43458284858 71730.62429520427 1.0650127340354232 1.7037296874411731 1.1466188335351801 1.1545743069450831 1.011949765731523 0.9027888005490525 1.310930925859917 1.2501882314327146 1.290807594282139 1.0 16.130301566624006 -5.467852525235314 24.999064376961613 1.1361830576307932 1.3945723103929324 0.21813449950864794 0.18984767470642708 417.00751349513246 189450.2669815964 0.0489556515289691 0.10190859326153397 3.4052380282594817e-06 5.467852525235314 0.2583892527621392 DPYGS(ph)LDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DPYGSLDR 8 0 A1BQX2;A0A0G2JQ38;D6RA09;A0A0G2JN23;Q8N4S9-2;Q8N4S9-3;Q8N4S9 A1BQX2 MARVELD2 MARVEL domain-containing protein 2 1 DPYGS(1)LDR;DPYGS(1)LDR 80.916 0.018622 6753400.0 29938.0 29823.0 30551.0 31746.0 49064.0 36272.0 32441.0 32577.0 27909.0 24762.0 True False 35005.91209754699 32783.63034665932 31279.451705312717 29967.374541920675 39450.261408871025 34369.832466793356 29367.953627499206 31721.88826818465 28317.11632635937 29251.154584115848 1.1967360808573393 1.1207636352399473 1.0693407542380664 1.0244851859007902 1.3486736496306906 1.1749906270522765 1.003992972073888 1.0844661935296898 0.9680683285485188 1.0 14.836205950566988 -7.262680628288868 24.99999996015986 1.021170717874021 1.1531015032004237 0.397067125875318 0.08532572334020345 135.72706885184405 2733641.2033013217 0.036517106556186035 0.02618195903463421 5.461593484073988e-08 7.262680628288868 0.13193078532640268 DPYGS(ph)LDR ddPTM_PC-9_Lapatinib_30min_R1 3 DPYGSLDR 8 0 A1BQX2;A0A0G2JQ38;D6RA09;A0A0G2JN23;Q8N4S9-2;Q8N4S9-3;Q8N4S9 A1BQX2 MARVELD2 MARVEL domain-containing protein 2 1 DPY(0.001)GS(0.999)LDR;DPYGS(1)LDR;DPY(0.001)GS(0.999)LDR 81.525 0.017759999999999998 11598600.0 72024.0 97539.0 63519.0 27904.9 54569.0 46524.0 37234.0 39043.0 64700.0 29279.9 True False 70996.92455241604 97313.15443827823 58296.71301043064 29957.11943401754 51359.358706781815 44534.27697274104 39161.794332638776 40857.08031347901 57412.804678795714 34340.89170198565 2.0674164540785895 2.833739883133303 1.6975887963637188 0.8723454153138768 1.4955744059439238 1.2968293706294758 1.140383734717476 1.1897501284486618 1.6718495599074965 1.0 15.067639880663823 -5.472542776169722 5.023097705028111 1.254914523079882 2.4318009879991767 0.7517253725640978 0.27622304308415796 0.08891551873359337 4.969351487761158 0.06920150432250932 0.14397397767132059 3.3686603422772165e-06 5.472542776169722 1.1768864649192947 DQALTEEHAR ddPTM_PC-9_AZD4547_30min_R2 1 DQALTEEHAR 10 0 P12814-4;P12814-3;P12814;P12814-2;H9KV75;H0YJ11 P12814-4 ACTN1 Alpha-actinin-1 0 101.35 0.0030518 2711400.0 19834.0 17325.0 24852.0 29741.0 28641.0 25100.0 22320.0 36120.0 20293.0 24089.0 False True 26140.799427171587 22924.967441159555 24522.446241991667 22884.671943869518 24664.69152964654 23530.493032117272 24306.436760430635 30538.483955027958 21365.646551019407 23245.651442120965 1.1245457883707501 0.986204559516868 1.0549261784747042 0.9844710956304992 1.0610453998701144 1.0122535430209616 1.0456337100705009 1.3137288938133362 0.9191244480378381 1.0 14.504673236430124 -7.551347327557912 24.99908802890999 1.105792160990457 1.033952912375715 0.00799863990516736 0.10190911108562804 512.3908478099343 449939.3263995001 0.04440561863829718 0.025637991321960377 2.8096529081837334e-08 7.551347327557912 -0.07183924861474211 DQALTEEHAR ddPTM_PC-9_Lapatinib_30min_R1 1 DQALTEEHAR 10 0 P12814-4;P12814-3;P12814;P12814-2;H9KV75;H0YJ11 P12814-4 ACTN1 Alpha-actinin-1 0 93.839 0.0054866 3077600.0 32136.0 36103.0 36891.0 33232.0 34061.0 33927.0 37058.0 38052.0 36492.0 31164.0 False True 31677.73474697937 36019.40572166171 33857.96438337814 35675.99213870218 32057.59894650251 32476.021297699775 38976.68191381342 39820.03483565566 32381.88668220421 36550.65587658022 0.8666803368438823 0.9854653728591801 0.9263298721014903 0.976069820994964 0.8770731517035066 0.8885208902231695 1.0663743503105694 1.089447887614249 0.8859454339628652 1.0 15.157609674137557 -7.256557955277463 24.992810437492935 1.017895908945122 0.923879842868464 0.3343900965979517 0.061997193681489975 469.9672500708095 2406231.448769463 0.024019181129052564 0.018026687548175015 5.539136209186256e-08 7.256557955277463 -0.09401606607665802 DQDMS(ph)SPTTMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DQDMSSPTTMK 11 0 Q5VW31;A0A1B0GWB8;A0A2R8Y7V8;Q5VW30;Q5VW27;A0A1B0GWI9;A0A1B0GU97;A0A0A0MRX8;A0A1B0GWJ4;A0A1B0GVN4;U3KQE8;A0A1B0GW37;Q5VW26;O00712-4;O00712;O00712-5;O00712-6 Q5VW31 NFIB Nuclear factor 1;Nuclear factor 1 B-type 1 DQDMS(0.409)S(0.141)PT(0.409)T(0.041)MK 62.732 0.032172000000000006 3445300.0 17478.0 22511.0 21345.0 23269.0 25024.0 17431.0 21816.0 16351.0 16861.0 16099.0 True False 20436.680193764663 24745.74330998383 21853.945751363273 21965.313369115855 20120.726836287067 16516.887674478246 19749.43054583777 15921.803575316551 17107.560227121907 19017.621260386113 1.0746181088554152 1.3012007638163166 1.1491419169696713 1.1549979394568033 1.0580043929152556 0.86850439644011 1.038480589945075 0.8372132012367824 0.8995636201230445 1.0 14.215049183557522 -6.460342037691474 2.3190471555160124 0.9245037750659336 1.1821508325789158 0.6836829206312982 0.07685009774651577 0.16403605544149663 1.7487418762838494 0.02605137220741983 0.029152158809786062 3.464638781093986e-07 6.460342037691474 0.2576470575129822 DQDMS(ph)SPTTMK ddPTM_PC-9_Lapatinib_30min_R1 2 DQDMSSPTTMK 11 0 Q5VW31;A0A1B0GWB8;A0A2R8Y7V8;Q5VW30;Q5VW27;A0A1B0GWI9;A0A1B0GU97;A0A0A0MRX8;A0A1B0GWJ4;A0A1B0GVN4;U3KQE8;A0A1B0GW37;Q5VW26;O00712-4;O00712;O00712-5;O00712-6 Q5VW31 NFIB Nuclear factor 1;Nuclear factor 1 B-type 1 DQDMS(0.635)S(0.23)PT(0.105)T(0.03)MK;DQDMS(0.302)S(0.093)PT(0.302)T(0.302)MK 89.43 0.0092867 10052100.0 38020.0 61447.0 56790.0 54759.0 69181.0 68810.0 64896.0 66676.0 64889.0 57411.0 True False 37477.8278279859 61304.72324679242 52120.945415739436 58786.159530669036 65111.909595079116 65867.15670394438 68255.99734143325 69774.01037270526 57580.517508537465 67334.41485465107 0.5565924632876965 0.9104515629804696 0.7740610136473062 0.8730477521422826 0.9669930263095108 0.9782093873708722 1.0136866487779173 1.0362310346547206 0.8551424651544312 1.0 16.03905643935972 -4.067844365774568 0.5852034587217025 0.9819426744540213 5.33582251883434e-13 0.6891561395617596 0.07656684376367869 4.696764745431918 0.6587609274406239 0.036998354226345204 3.751646537454106 8.553731903990649e-05 4.067844365774568 -0.9819426744534877 DQDMSSPT(ph)TMK ddPTM_PC-9_Lapatinib_30min_R1 1 DQDMSSPTTMK 11 0 Q5VW31;A0A1B0GWB8;A0A2R8Y7V8;Q5VW30;Q5VW27;A0A1B0GWI9;A0A1B0GU97;A0A0A0MRX8;A0A1B0GWJ4;A0A1B0GVN4;U3KQE8;A0A1B0GW37;Q5VW26;O00712-4;O00712;O00712-5;O00712-6 Q5VW31 NFIB Nuclear factor 1;Nuclear factor 1 B-type 1 DQDMS(0.068)S(0.112)PT(0.41)T(0.41)MK 72.73100000000001 0.023534 7610700.0 17835.0 28479.0 25485.0 26140.0 30580.0 28610.0 28534.0 29034.0 27898.0 25032.0 True False 17580.66962946157 28413.058625244536 23389.72167494489 28062.422800483753 28781.344522593186 27386.416993167422 30011.35090206571 30383.02563382806 24755.833461036207 29358.74784695661 0.5988221882318465 0.9677885028802377 0.7966866229061441 0.9558453564426375 0.9803328354678696 0.9328196534787282 1.0222285725028546 1.0348883335287622 0.8432183003881908 1.0 14.841502817978915 -4.393738536184706 1.8718272880352276 0.9529352026017389 9.737085949735303e-35 0.6552887489241408 0.07454958554220559 2.041537232555033 2.835009876967109 0.019984206640168423 4.888675611707756 4.038884778895575e-05 4.393738536184706 -0.9529352026017389 DQEFTVK ddPTM_PC-9_Lapatinib_30min_R1 1 DQEFTVK 7 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 90.709 0.026719999999999997 0.0 18767.0 20176.0 18003.0 15343.0 22331.0 15876.0 19140.0 19126.0 18507.0 20196.0 False True 18499.37913855369 20129.28371160974 16522.86283358967 16471.37540274758 21017.534484435208 15197.020488763581 20130.975547260754 20014.66378289577 16422.546772650265 23686.851690521566 0.7809978033491182 0.8498083229720474 0.6975541979773272 0.6953805266294085 0.8873080626770462 0.6415804298232154 0.8498797480678398 0.8449693544923387 0.6933191032399567 1.0 14.531798836789099 -11.545446922176705 2.482951640800141 1.2580109952486422 0.7732021548793006 0.41831828178863995 0.08090971611456974 10696165.226438958 4445281.376435695 15719777.687536223 0.019898856168846082 2.8480858611485422e-12 11.545446922176705 -0.4848088403693417 DQEPDVHYDFEPHVS(ph)ANAWSPVMR ddPTM_PC-9_AZD4547_30min_R2 1 DQEPDVHYDFEPHVSANAWSPVMR 24 0 Q92619;K7ES92;F5H1R4;K7ES98;K7EM85;Q92619-2 Q92619 HMHA1 Minor histocompatibility protein HA-1;Minor histocompatibility antigen HA-1 1 DQEPDVHYDFEPHVS(0.5)ANAWS(0.5)PVMR 52.522 0.011717 2410300.0 3701.0 2983.0 6013.1 10626.0 7683.7 8166.6 3620.8 8280.8 3415.8 7264.4 True False 4877.841014417766 3947.196414255643 5933.362365110254 8176.339870063464 6616.9508853163325 7655.941210999555 3943.0441855809695 7001.19263385369 3596.3522145060883 7010.075567111273 0.6958328719454643 0.5630747310021099 0.8464049079509833 1.1663697190974487 0.9439200507852813 1.0921339060763409 0.5624824080471115 0.9987328334520017 0.5130261692725349 1.0 12.775214280924958 -5.360763109955187 5.45370269761134 0.9002383371202577 0.6315177589666738 0.21454582839560077 0.20075123001920014 0.3134431411366535 13.692178200005845 0.052515028652258926 0.11248132965916437 4.357494925681228e-06 5.360763109955187 -0.26872057815358386 DQEWYDAEIAR ddPTM_PC-9_AZD4547_30min_R2 1 DQEWYDAEIAR 11 0 Q8IVM0-2;Q8IVM0 Q8IVM0-2 CCDC50 Coiled-coil domain-containing protein 50 0 103.43 0.010798 0.0 5398.6 5239.5 7102.6 9658.6 9635.4 8910.2 7774.9 8762.5 7601.8 8961.2 False True 7115.2425021442195 6933.065910993101 7008.414883243601 7431.958993882462 8297.69102911059 8353.04378544906 8466.851038022936 7408.456967218508 8003.615628617719 8647.471115576996 0.822811942017046 0.8017449053405132 0.8104583166076259 0.8594372729959179 0.9595511703026871 0.9659522042695725 0.9791129597150429 0.8567194811293896 0.9255440719773579 1.0 13.078062574355009 -6.067598019860155 3.1772196715432637 0.9429686349620375 0.8116791099512117 0.7395438802517401 0.03677377482402566 0.14119239339529518 2.7938218530657544 0.011909722939959911 0.01667942257638147 8.558585234479333e-07 6.067598019860155 -0.1312895250108258 DQGFRGDGGSTTGLSAT(ph)PPASLPGSLTNVK ddPTM_PC-9_AZD4547_30min_R2 1 DQGFRGDGGSTTGLSATPPASLPGSLTNVK 30 1 H7C560;P15056;A0A2R8Y679;A0A2R8Y492;A0A2R8YDP5 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 DQGFRGDGGSTTGLS(0.007)AT(0.993)PPASLPGSLTNVK 109.17 2.2668000000000005e-15 17679000.0 58957.0 28493.0 84070.0 169480.0 130040.0 81200.0 47668.0 75365.0 55131.0 84067.0 True False 77704.09961821884 37702.805039016435 82955.17686963781 130409.00443989808 111986.19065379103 76122.55116366218 51910.359654847976 63719.070965412 58045.112107832756 81123.83991800317 0.9578454335588543 0.4647561688046938 1.0225745841602873 1.6075299760429296 1.380435033240319 0.9383499504042696 0.6398903171659152 0.7854543255079736 0.7155123841093136 1.0 16.3078383220725 -7.00227761505389 24.958005011299637 0.7704475204199405 1.0856534708876813 0.19359693720588322 0.28949285894995463 164.2510276484096 1799875.55614322 0.11743202729615526 0.10187097020332646 9.947693253993287e-08 7.00227761505389 0.3152059504677408 DQGFRGDGGSTTGLSAT(ph)PPASLPGSLTNVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DQGFRGDGGSTTGLSATPPASLPGSLTNVK 30 1 H7C560;P15056;A0A2R8Y679;A0A2R8Y492;A0A2R8YDP5 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 DQGFRGDGGS(0.001)T(0.003)T(0.003)GLS(0.008)AT(0.983)PPAS(0.003)LPGSLTNVK 84.09700000000001 1.0068999999999999e-08 8169700.0 44201.0 21955.0 37985.0 56596.0 59453.0 71100.0 55629.0 67598.0 66456.0 52587.0 True False 51683.3562904561 24134.547304459815 38890.706458914705 53425.109606707694 47803.61143693153 67371.3908356034 50359.418400917195 65823.62412600151 67427.79327760011 62120.606821537025 0.8319840860366102 0.3885111324458672 0.6260516187590012 0.8600223394499322 0.7695290481347675 1.0845256394412093 0.8106717074672513 1.059610127684404 1.0854335900373577 1.0 15.922784302226148 -6.189014047595462 1.1006478440628418 1.0064288136749675 0.585322030377299 0.5780710893978178 0.13754943092291583 0.3469877084215795 0.8699937986067553 0.05673563091322171 0.09233289079878872 6.471216837519123e-07 6.189014047595462 -0.4211067832976685 DQGFRGDGGSTTGLSAT(ph)PPASLPGSLTNVK ddPTM_PC-9_Lapatinib_30min_R1 2 DQGFRGDGGSTTGLSATPPASLPGSLTNVK 30 1 H7C560;P15056;A0A2R8Y679;A0A2R8Y492;A0A2R8YDP5 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 DQGFRGDGGSTTGLS(0.002)AT(0.989)PPAS(0.009)LPGSLTNVK;DQGFRGDGGS(0.001)T(0.002)T(0.002)GLS(0.035)AT(0.96)PPASLPGSLTNVK 94.588 2.8677e-12 21639600.0 214609.0 95010.0 115218.0 96134.0 95478.0 99773.0 62098.0 61810.0 115665.0 65755.0 True False 211548.63630552893 94790.01018239684 105745.22079434163 103204.01505362288 89862.17175697039 95505.94137222262 65313.13059215246 64681.91824849877 102637.58969355327 77120.6641369698 2.743086287869733 1.2291129912217233 1.3711658474119635 1.3382148119254764 1.1652152216605798 1.2383962513937863 0.8468953337351112 0.8387105968592379 1.3308701479964467 1.0 16.23482985517058 -2.9440960203085553 1.3202373538403274 1.1136406989500944 199.99999962026916 0.8586284662317551 0.19260370541395386 64.98107944751942 1.2146678453126192 0.05857817308134831 38136.90253994681 0.0011373757900002997 2.9440960203085553 198.88635892131907 up DQGGELLSLR ddPTM_PC-9_Lapatinib_30min_R1 1 DQGGELLSLR 10 0 P12081-3;P12081-2;P12081-4;P12081;A0A2R8Y4X6;D6RJE6;A0A2R8Y6I1;B3KWE1;A0A2R8Y5E8;A0A2R8Y3N3;A0A2R8Y5P7;P49590-2;P49590 P12081-3;A0A2R8Y5E8 HARS;HARS2 Histidine--tRNA ligase, cytoplasmic;Probable histidine--tRNA ligase, mitochondrial 0 99.973 0.019199 1615800.0 24946.0 22234.0 25834.0 19811.0 27200.0 25930.0 22279.0 17045.0 24237.0 16952.0 False True 24590.265465463894 22182.5185390529 23710.02824212385 21267.967027558658 25600.14947725752 24821.034345782286 23432.497608015798 17836.972925831764 21507.173833075292 19882.130612879853 1.236802329903922 1.1157012782464486 1.1925295484561522 1.0697026109355223 1.287595880728873 1.2484091785265186 1.1785707510057286 0.897135889162542 1.0817338569912984 1.0 14.279184747110163 -7.713464871858719 11.012525364891864 0.992188109875432 1.1886665790997117 0.6085989503125985 0.07237265404543834 0.3673060962111058 82.98192158315715 0.03390904487241365 0.019526583389249022 1.934350313250653e-08 7.713464871858719 0.1964784692242797 DQGGFGDRNEYGSR ddPTM_PC-9_AZD4547_30min_R2 1 DQGGFGDRNEYGSR 14 1 A0A087WTP3;Q92945;M0R0I5 A0A087WTP3 KHSRP Far upstream element-binding protein 2 0 86.262 0.008517100000000001 14594000.0 13684.0 13418.0 17495.0 29054.0 21159.0 23751.0 15483.0 19005.0 14199.0 17845.0 False True 18035.22735511827 17755.106096708758 17263.004868970067 22356.04917982532 18221.438080925644 22265.84621537121 16860.957005454628 16068.213941453647 14949.530152166977 17220.25198159527 1.0473265649302945 1.0310595986449635 1.0024827097431845 1.2982416984210863 1.0581400376951757 1.2930035076820356 0.9791353241215837 0.9330998151843015 0.8681365503910626 1.0 14.07181863319815 -7.502952431155905 23.49761551199793 0.9315943483685407 1.1188677427386733 0.4298430910904778 0.10063225759980036 336.1431359113332 396391.02315091103 0.04324741853775612 0.02866325155803295 3.1408526967508165e-08 7.502952431155905 0.18727339437013257 DQGGFGDRNEYGSR ddPTM_PC-9_Lapatinib_30min_R1 1 DQGGFGDRNEYGSR 14 1 A0A087WTP3;Q92945;M0R0I5 A0A087WTP3 KHSRP Far upstream element-binding protein 2 0 76.72800000000001 0.020692 11334000.0 15864.0 11910.0 17295.0 13203.0 12148.0 13405.0 9312.1 13384.0 15168.0 12511.0 False True 15637.776450898707 11882.423126748223 15873.07186063064 14173.992663916855 11433.47852388692 12831.699398581244 9794.234973544762 14005.869500694187 13459.620113879018 14673.509680140378 1.065714801146954 0.8097873914125872 1.0817501883761176 0.9659579046109475 0.7791918070808497 0.8744805897356717 0.6674773239016301 0.9545003074247603 0.917273399975721 1.0 13.840926362526769 -4.744127249540369 24.640401358004716 0.8898317209538319 1.065715438223365 0.1698297162504484 0.11314833176668171 1707.6957533510524 2430412.018194609 0.02893719656070009 0.8379320863957497 1.80248952882983e-05 4.744127249540369 0.175883717269533 DQGTYEDYVEGLR ddPTM_PC-9_AZD4547_30min_R2 3 DQGTYEDYVEGLR 13 0 F8W1R7;G3V1V0;P60660-2;P60660;J3KND3;G8JLA2;B7Z6Z4;G3V1Y7;F8VPF3;F8VZU9;F8W180;H0YI43 F8W1R7 MYL6 Myosin light polypeptide 6 0 ;; 188.96 0.00010011 16498500.0 34564.7 35041.1 44526.9 43447.0 43481.6 45725.5 40088.9 47038.8 42174.7 39805.2 False True 45555.55560957738 46367.45030894179 43936.44421264037 33430.96539945864 37444.930387049295 42866.277256576795 43656.73443751017 39770.034304091045 44403.968540643495 38411.63206375992 1.1859833379107447 1.2071200263497244 1.1438317471048807 0.8703344170319602 0.9748331006840327 1.1159712554109276 1.136549844199378 1.0353643458334783 1.156003172865366 1.0 15.229255643087022 -5.535806551805995 24.98539646336446 1.0440020338107727 1.1912827870690972 0.39547173607476804 0.07970156496923687 232.35422105573952 449066.3429155616 0.023284039284092433 0.04035923152817699 2.912013930291715e-06 5.535806551805995 0.14728075325832446 DQGTYEDYVEGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DQGTYEDYVEGLR 13 0 F8W1R7;G3V1V0;P60660-2;P60660;J3KND3;G8JLA2;B7Z6Z4;G3V1Y7;F8VPF3;F8VZU9;F8W180;H0YI43 F8W1R7 MYL6 Myosin light polypeptide 6 0 ;; 153.81 3.7976999999999997e-08 9881700.0 31422.7 51887.0 43845.8 44180.0 47429.0 32737.2 41137.5 34146.8 32237.0 31450.2 False True 36741.94248338533 57037.99845076321 44891.25015812246 41704.73783349255 38135.6279219253 31020.40360145309 37240.65819029156 33250.482681525245 32708.405138587786 37151.87230035377 0.9889661061048455 1.53526578659725 1.2083173035049164 1.1225474047803354 1.0264793013288367 0.834962053881675 1.0023898093000536 0.8949880752364835 0.8803972212801865 1.0 15.181147297994901 -6.121214830149761 1.7433899441149814 0.9224471240609808 1.2753313720713477 0.5203199048743051 0.13392024501165997 0.25883898491387586 1.562677699589906 0.04382727563097134 0.06528337903954552 7.564586090843852e-07 6.121214830149761 0.3528842480103669 DQGTYEDYVEGLR ddPTM_PC-9_Lapatinib_30min_R1 4 DQGTYEDYVEGLR 13 0 F8W1R7;G3V1V0;P60660-2;P60660;J3KND3;G8JLA2;B7Z6Z4;G3V1Y7;F8VPF3;F8VZU9;F8W180;H0YI43 F8W1R7 MYL6 Myosin light polypeptide 6 0 ;;; 211.22 8.8758e-10 34967400.0 48732.1 75487.2 78309.0 71878.4 81056.7 81320.2 78881.1 78191.5 80713.8 72976.9 False True 48037.17131762735 75312.41402631972 71870.73630148172 77164.57731531313 76289.10426960367 77842.32461264497 82965.17738981338 81824.56254210451 71622.9618900058 85590.85992939319 0.5612418353695108 0.8799118748012053 0.839701065753637 0.9015516070170204 0.891323025992929 0.9094700611357305 0.9693228629581965 0.9559965002057974 0.8368061957677492 1.0 16.385169121986813 -4.390269767908875 1.5932407480739468 0.9153316412629341 3.736734038644732e-20 0.8122462665823761 0.05023594036266733 1.3174569900625293 1.4039611030657815 0.013704272743594979 2.5479170263300714 4.071273065946028e-05 4.390269767908875 -0.9153316412629341 DQHHLGS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 2 DQHHLGSPSR 10 0 Q9H8M2-2;Q9H8M2-3;Q9H8M2-1;Q9H8M2-6;Q9H8M2 Q9H8M2-2 BRD9 Bromodomain-containing protein 9 1 DQHHLGS(0.985)PS(0.015)R;DQHHLGS(0.93)PS(0.07)R 71.531 0.018659000000000002 48997700.0 38561.0 32632.0 65328.0 91002.0 69046.0 65633.0 58191.0 79912.0 66011.0 67223.0 True False 50822.59588137353 43179.65584645999 64461.70803544305 70022.89486688463 59460.15472071419 61528.958134539986 63369.886269095834 67563.43659507745 69500.20669587253 64869.543231088704 0.7834585130393953 0.6656383519248545 0.9937129941829127 1.0794417746620757 0.9166112748612346 0.94850302730438 0.9768819558872096 1.0415278608389784 1.071384246506681 1.0 15.985253659886245 -5.27009850846472 24.694717189830435 1.0016841304699975 0.7245484308351429 0.8048667221650648 0.05493616619193882 194.95765357009975 555995.273740123 0.014918196640569951 0.03184682922604367 5.369099984182202e-06 5.27009850846472 -0.2771356996348546 DQHHLGS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DQHHLGSPSR 10 0 Q9H8M2-2;Q9H8M2-3;Q9H8M2-1;Q9H8M2-6;Q9H8M2 Q9H8M2-2 BRD9 Bromodomain-containing protein 9 1 DQHHLGS(0.99)PS(0.01)R 64.798 0.028607 35963000.0 20965.0 18444.0 32953.0 33895.0 38580.0 33369.0 37040.0 32082.0 33722.0 28323.0 True False 24513.960422375338 20274.998427850467 33738.724494948445 31995.973039072676 31020.525948847273 31619.070897232774 33531.30305362262 31239.88149368879 34215.12045424381 33457.73569525537 0.73268438263895 0.6059883613321048 1.0083983208622491 0.9563101738415016 0.9271555681888624 0.94504515144809 1.0021988146190564 0.9337117663380582 1.0226370596589969 1.0 15.030052191579534 -5.2642939867145655 24.999995962275268 0.9696711498718923 0.6693363585917497 0.8910153278197451 0.04265516992235884 62.205901259806936 544790.05562208 0.010472841622405847 0.023451253919398327 5.441341877004255e-06 5.2642939867145655 -0.3003347912801426 DQHHLGS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 2 DQHHLGSPSR 10 0 Q9H8M2-2;Q9H8M2-3;Q9H8M2-1;Q9H8M2-6;Q9H8M2 Q9H8M2-2 BRD9 Bromodomain-containing protein 9 1 DQHHLGS(0.818)PS(0.182)R;DQHHLGS(0.885)PS(0.115)R 65.472 0.027612 53149300.0 56226.0 47610.0 73888.0 54289.0 71678.0 70793.0 57649.0 63567.0 86345.0 54119.0 True False 55424.20692941441 47499.761970149666 67813.21385592803 58281.59416279497 67462.04096436998 67765.34841654325 60633.78314127663 66520.55488274268 76619.91684684104 63473.397040965356 0.8731879734378161 0.7483412608197667 1.0683722160350388 0.9182050572333537 1.0628396164274991 1.0676181136611909 0.9552629285327827 1.0480068498588584 1.207118579101588 1.0 15.953864436019304 -5.266236272602292 24.965019052576476 1.0369358134606552 0.8107646107409776 0.5787122332951857 0.07849233670741264 247.77375469805708 1289523.4269319416 0.02037153141306498 0.0447022390247 5.417061016402122e-06 5.266236272602292 -0.2261712027196776 DQHHLGSPS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 DQHHLGSPSR 10 0 Q9H8M2-2;Q9H8M2-3;Q9H8M2-1;Q9H8M2-6;Q9H8M2 Q9H8M2-2 BRD9 Bromodomain-containing protein 9 1 DQHHLGS(0.177)PS(0.823)R 62.077 0.034614 6810100.0 12976.0 17697.0 18733.0 16268.0 19706.0 18289.0 18136.0 20867.0 21873.0 16122.0 True False 12790.959860493036 17656.02368380043 17192.84505147115 17464.402988457132 18546.93182348663 17506.822103741306 19074.993339870478 21836.556998728738 19409.43240709888 18908.666218785325 0.6764601856362302 0.933752993442741 0.9092574194572463 0.9236189790640362 0.9808693859676194 0.9258623480459283 1.0087963433888272 1.1548438555139664 1.0264834220732109 1.0 14.206759981472315 -3.5011971400014663 0.397674275253198 1.0483271402017176 1.1225285863303857e-14 0.6937191790194972 0.06372522799481181 9.407394151490495 0.5282644339571732 0.05090834105723158 5.785785010888703 0.00031535727919890314 3.5011971400014663 -1.0483271402017063 DQHLNNS(ph)SSSPQR ddPTM_PC-9_Lapatinib_30min_R1 2 DQHLNNSSSSPQR 13 0 A0A5H1ZRS1;A0A4W8VX11;E9PGW9;E7EV93 A0A5H1ZRS1 PCM1 1 DQHLNNS(0.96)S(0.021)S(0.009)S(0.009)PQR;DQHLNNS(0.425)S(0.258)S(0.159)S(0.159)PQR 171.26 0.00022569999999999996 3560400.0 4650.3 3116.88 4966.6 2773.9500000000003 4063.6400000000003 4146.650000000001 3118.67 3097.14 4339.55 3367.0 True False 4583.985869239422 3109.663055860538 4558.26531963042 2977.9555366259324 3824.6246846236318 3969.3074458132687 3280.1394728304936 3241.044431065448 3850.7841815126426 3948.981463754509 1.1608020729682484 0.7874595220064705 1.1542888619428038 0.754107246123822 0.9685091509615128 1.0051471454716414 0.8306292402071416 0.8207292084840562 0.9751335165426416 1.0 11.947264880565639 -4.739927215369066 24.776712550590997 0.9194194653365867 1.1608030977016983 0.27287097561123463 0.11699786074070943 1995.862892791944 2298609.620474917 0.027422123487554757 1.282205890952157 1.8200058529400126e-05 4.739927215369066 0.24138363236511162 DQHLNNSS(ph)SSPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DQHLNNSSSSPQR 13 0 A0A5H1ZRS1;A0A4W8VX11;E9PGW9;E7EV93 A0A5H1ZRS1 PCM1 1 DQHLNNS(0.008)S(0.885)S(0.096)S(0.011)PQR 176.43 0.00015189 3861100.0 4766.5 4203.4 7829.5 6227.9 9802.5 8257.6 7555.1 6082.1 6161.7 5767.5 True False 5573.374307333743 4620.685772697171 8016.184973544105 5878.970954124225 7881.770492835036 7824.556919326004 6839.426233812748 5922.451319517634 6251.803205708854 6813.102094495119 0.8180376912063219 0.6782058610908845 1.1765837150776088 0.862891950331163 1.1568548927519204 1.1484573122202477 1.0038637523630973 0.8692738252525063 0.9176147838383656 1.0 12.734096110409142 -5.2491963901686125 24.99894649632146 1.0159986601730842 0.7481217542377828 0.47457892765632315 0.11313809237045831 671.1377226875187 1370389.3192431196 0.029683813795676594 0.07728416036440133 5.6338283363800735e-06 5.2491963901686125 -0.26787690593530133 DQHLNNSSS(ph)SPQR ddPTM_PC-9_AZD4547_30min_R2 1 DQHLNNSSSSPQR 13 0 A0A5H1ZRS1;A0A4W8VX11;E9PGW9;E7EV93 A0A5H1ZRS1 PCM1 1 DQHLNNSS(0.1)S(0.8)S(0.1)PQR 144.88 9.4462e-05 11480000.0 5737.1 8180.1 13959.0 20241.0 17034.0 15444.0 9951.2 17860.0 9695.8 11915.0 True False 7561.378460906832 10824.157354425934 13773.894539351435 15574.75017033263 14669.123128242692 14478.284238566488 10836.837521971202 15100.147381971174 10208.300193631987 11497.85947664375 0.6576335774729797 0.9414063005739158 1.1979529378777956 1.3545782327545834 1.2758133944879835 1.2592156190443136 0.9425091291109167 1.313300741989842 0.8878435342133623 1.0 13.4890776833394 -4.931191770997637 2.5507119253415578 1.172009310594097 0.6260009050241382 0.4995149708327894 0.15401203414587794 0.2890011864204749 3.0758077803614325 0.040090222164458324 0.2998500003546635 1.1716778746277637e-05 4.931191770997637 -0.5460084055699588 DQHLNNSSSS(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 3 DQHLNNSSSSPQR 13 0 A0A5H1ZRS1;A0A4W8VX11;E9PGW9;E7EV93 A0A5H1ZRS1 PCM1 1 DQHLNNS(0.004)S(0.039)S(0.039)S(0.918)PQR;DQHLNNS(0.113)S(0.146)S(0.079)S(0.662)PQR;DQHLNNSS(0.001)S(0.002)S(0.997)PQR 236.03 6.202100000000001e-26 24780400.0 31098.6 28024.399999999998 58882.0 83513.0 68685.0 58467.0 49015.5 77155.0 50805.0 59463.0 True False 40987.307908936076 37082.739252988875 58101.18620718469 64260.36811298803 59149.27333940053 54811.04924736252 53377.7845443946 65232.46759552 53490.44857953681 57381.218469128595 0.7142983192486139 0.6462522100840293 1.0125470974173099 1.1198850395196898 1.0308124316185994 0.9552088768705942 0.9302309356346647 1.13682611376779 0.9321943661463892 1.0 15.808290983081353 -5.265619477573736 24.83213787373369 1.018788510226308 0.6802752478580901 0.7940246085784914 0.06810904661210161 119.97470973607136 712722.1924122974 0.017828201110654137 0.0393650932416996 5.424759917040822e-06 5.265619477573736 -0.33851326236821777 DQHLNNSSSS(ph)PQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DQHLNNSSSSPQR 13 0 A0A5H1ZRS1;A0A4W8VX11;E9PGW9;E7EV93 A0A5H1ZRS1 PCM1 1 DQHLNNS(0.104)S(0.055)S(0.189)S(0.652)PQR;DQHLNNSS(0.002)S(0.078)S(0.92)PQR;DQHLNNSS(0.003)S(0.08)S(0.918)PQR 227.91 1.2024000000000001e-19 21121900.0 17476.4 21805.4 34544.0 32715.6 40418.1 37429.9 34004.1 31761.300000000003 35480.5 26221.800000000003 True False 20434.809345366084 23970.096005131774 35367.65996884951 30882.650997406276 32498.463448758543 35467.01015242688 30782.98547963523 30927.59952887907 35999.33518998863 30975.604768345427 0.6597065496602931 0.7738378696524202 1.1417907812728942 0.9969991297463175 1.049163162165904 1.1449981499205888 0.9937815810167155 0.998450224303113 1.1621834491760126 1.0 14.918844829397989 -5.125901325816474 4.178529808553587 1.0582547421337565 0.6826550868478777 0.8210483222337566 0.06501731876899965 0.08228581212267962 2.3388245683740148 0.016346465313738835 0.049980194184337884 7.4833950820189405e-06 5.125901325816474 -0.3755996552858788 DQHLNNSSSS(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 3 DQHLNNSSSSPQR 13 0 A0A5H1ZRS1;A0A4W8VX11;E9PGW9;E7EV93 A0A5H1ZRS1 PCM1 1 DQHLNNS(0.021)S(0.045)S(0.231)S(0.703)PQR;DQHLNNS(0.005)S(0.005)S(0.204)S(0.787)PQR;DQHLNNSSS(0.002)S(0.997)PQR 241.39 1.2048e-26 25259800.0 44212.4 33761.6 50004.0 39384.4 51425.4 46128.2 42201.200000000004 45545.2 58442.0 34580.1 True False 43581.923068438846 33683.427089506535 45892.86414102196 42280.86015850697 48400.65907822644 44155.40441608615 44386.17164394253 47661.396262927134 51859.64653845714 40557.22420991307 1.074578547162665 0.8305160854986119 1.131558311374888 1.042498863819497 1.1933918067892888 1.0887186013409076 1.0944085180536982 1.1751641585786252 1.2786783994399082 1.0 15.30767129531204 -5.2909627051610535 24.2175621449313 1.128837098321449 0.9525473265137057 0.35885996822649424 0.09241465564658743 413.1884680924017 338931.9325960033 0.023259002001124775 0.0484316384118724 5.117257778694021e-06 5.2909627051610535 -0.1762897718077434 DQIYDIFQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DQIYDIFQK 9 0 P60842;P60842-2;J3KT12;J3QL43;J3QS69;J3KTB5;J3QR64;J3KSZ0;J3KTN0 P60842 EIF4A1 Eukaryotic initiation factor 4A-I 0 107.79 0.011422 1488100.0 13824.0 16609.0 16631.0 21046.0 16911.0 17872.0 14544.0 17109.0 14012.0 11559.0 False True 16164.130163554324 18257.831754942992 17027.54611341872 19866.86085205262 13597.41094662926 16934.76085814211 13166.287030558515 16659.906878483936 14216.898991900363 13654.55519900635 1.183790312315014 1.3371238746957956 1.2470231263672231 1.4549621399237043 0.9958150044769493 1.2402279394186682 0.9642413713715576 1.2200988341016255 1.0411836039107987 1.0 13.737094698219504 -6.270876939542279 24.990711555449067 1.09046342079959 1.3037746720354095 0.5170168998815745 0.10785362596590527 545.989440921575 1445780.3225971053 0.031101769760612966 0.03572595817917127 5.35948500852783e-07 6.270876939542279 0.2133112512358195 DQLIYNLLK ddPTM_PC-9_AZD4547_30min_R2 1 DQLIYNLLK 9 0 P00338-3;P00338;P00338-4;P00338-2;P00338-5;F5GYU2;F5GXY2;F5GXH2;F5GWW2;F5H8H6;F5H6W8;F5GZQ4;F5GXU1;F5GXC7;F5H5J4 P00338-3 LDHA L-lactate dehydrogenase A chain 0 129.38 0.0059886 3057300.0 17064.0 21784.0 22227.0 19193.0 19828.0 24789.0 26041.0 28390.0 22300.0 16571.0 False True 22489.99704675083 28825.25199066206 21932.255457136205 14768.350378894042 17075.224456193282 23238.939911281068 28358.598551898463 24002.977837299102 23478.73247364771 15990.854333819843 1.4064287359047245 1.8026086279641806 1.3715499496953456 0.9235498035686394 1.0678118942075565 1.4532644364180025 1.773426107191876 1.5010441178576697 1.4682600431167323 1.0 13.964959398432697 -11.58131180112798 2.4652679903100196 0.4181575212884771 1.4175613565557044 0.1942426893244943 0.25579848502150454 14436317.44262016 5209995.540912167 47287324.23290771 0.07308634539705212 2.622335165443534e-12 11.58131180112798 0.9994038352672272 DQLIYNLLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DQLIYNLLK 9 0 P00338-3;P00338;P00338-4;P00338-2;P00338-5;F5GYU2;F5GXY2;F5GXH2;F5GWW2;F5H8H6;F5H6W8;F5GZQ4;F5GXU1;F5GXC7;F5H5J4 P00338-3 LDHA L-lactate dehydrogenase A chain 0 ; 142.92 0.0029195999999999996 8694700.0 70036.0 89134.0 79494.0 75201.0 82124.0 68112.0 79233.0 58414.0 60182.0 65608.0 False True 81891.71152594704 97982.6344539159 81389.43844267387 70987.73177493167 66032.39173206688 64540.08681567681 71727.47664275582 56880.694394748985 61062.04789684187 77502.2110473576 1.0566371000165047 1.264255988697455 1.0501563419002458 0.9159446010069923 0.8520065536158432 0.8327515556458085 0.9254894237653021 0.7339235052273816 0.787874914427022 1.0 16.241949848924143 -5.718052465090036 2.3005443630686515 0.846182135988868 1.1625385059431532 0.6817836459059562 0.08368731065316924 0.15353624435589047 1.6528183524955251 0.024042536433776247 0.04691571927898736 1.914024686661977e-06 5.718052465090036 0.3163563699542852 DQLIYNLLK ddPTM_PC-9_Lapatinib_30min_R1 2 DQLIYNLLK 9 0 P00338-3;P00338;P00338-4;P00338-2;P00338-5;F5GYU2;F5GXY2;F5GXH2;F5GWW2;F5H8H6;F5H6W8;F5GZQ4;F5GXU1;F5GXC7;F5H5J4 P00338-3 LDHA L-lactate dehydrogenase A chain 0 ; 136.57 0.0045816 40882000.0 126087.0 131245.0 134749.0 125180.0 130885.0 106790.0 126042.0 122264.0 118532.0 133639.0 False True 124288.97625847625 130941.11026616853 123670.45736618206 134386.15478823817 123186.60162981057 102222.8406396486 132567.83803175748 127944.83178667582 105181.67796270484 156738.32308722535 0.7929712007274 0.835412218831124 0.7890250127108932 0.8573918116595638 0.7859379837900706 0.6521879182206209 0.8457908405590321 0.8162957805505813 0.6710654796540787 1.0 17.257998441536508 -10.862639496464627 3.4702679329178134 1.0010851596729569 0.785890479602581 0.49497882322507003 0.0657255649501692 51166904.826803155 77057792.3065002 575472.0750932553 0.016476985089389037 1.3720201939347436e-11 10.862639496464627 -0.2151946800703759 DQLYQQQYQWDPQLT(ph)PARPQGLFEK ddPTM_PC-9_AZD4547_30min_R2 2 DQLYQQQYQWDPQLTPARPQGLFEK 25 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 DQLYQQQYQWDPQLT(1)PARPQGLFEK;DQLYQQQYQWDPQLT(1)PARPQGLFEK 79.237 9.2187e-05 4749900.0 27949.0 26535.0 39367.0 52460.0 34964.0 36804.0 31420.0 46379.0 30055.0 44773.0 True False 36836.20062468582 35111.91982979332 38844.96785805916 40366.15749892051 30109.85212257119 34502.64006191409 34216.31913139473 39212.1912333954 31643.645941501425 43205.51089784055 0.8525810679981319 0.8126722517600931 0.8990743784955605 0.9342826102523428 0.6968984163563289 0.7985703523676783 0.7919433984312612 0.9075738353404187 0.7323983742796802 1.0 15.398927720593624 -11.044733461034328 3.0282026187621676 1.0061639631585426 0.8270293909871612 0.3459968689046642 0.07209036054530113 50743435.20564332 60984869.63250082 2595413.912427694 0.017786491420447616 9.021246274711903e-12 11.044733461034328 -0.1791345721713814 DQLYQQQYQWDPQLT(ph)PARPQGLFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DQLYQQQYQWDPQLTPARPQGLFEK 25 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 DQLY(0.002)QQQY(0.088)QWDPQLT(0.91)PARPQGLFEK 50.055 0.018514 3537800.0 10994.0 9925.9 6603.6 12344.0 11356.0 12516.0 15006.0 9720.8 12362.0 9539.6 True False 12855.067058602164 10911.277754012193 6761.054868292464 11652.405699787956 9130.873319728089 11859.63892684124 13584.52304596817 9465.639300038963 12542.770863393678 11269.053964567953 1.14074057139321 0.9682514422523243 0.5999665002537484 1.0340180938369214 0.8102608567176348 1.0524076789524834 1.2054714698039863 0.8399675189950045 1.113027846244284 1.0 13.460078786105386 -6.785575020515297 24.859286342038093 1.0423789761323166 0.9034415723000386 0.1453368388821561 0.15899639076856503 431.9634840458341 444911.4049019999 0.056219470791428194 0.04960609701978354 1.6384190145025212e-07 6.785575020515297 -0.13893740383227793 DQLYQQQYQWDPQLT(ph)PARPQGLFEK ddPTM_PC-9_Lapatinib_30min_R1 1 DQLYQQQYQWDPQLTPARPQGLFEK 25 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 DQLY(0.001)QQQY(0.014)QWDPQLT(0.985)PARPQGLFEK 64.152 0.00068743 3375900.0 31222.0 22387.0 29808.0 30023.0 24627.0 32067.0 21941.0 22142.0 28305.0 19406.0 True False 30776.768554586415 22335.164276953165 27357.30130220747 32230.991573792002 23178.488278544886 30695.569161828003 23076.997621862476 23170.798153345066 25116.992835136196 22760.301243130383 1.3522127069331122 0.9813211186602578 1.201974482234262 1.4161056670337395 1.0183735281421515 1.3486451182667312 1.0139144194687528 1.0180356536510509 1.1035439543102321 1.0 14.474232032057486 -7.291411657483767 24.65376841883622 1.0353764376623433 1.2078942286057073 0.3156808993208434 0.13339370078254315 789.1309724635472 649098.0776711726 0.054120687077024346 0.036494535123342095 5.111970542041757e-08 7.291411657483767 0.17251779094336395 DQMEGS(ph)PNSSESFEHIAR ddPTM_PC-9_AZD4547_30min_R2 1 DQMEGSPNSSESFEHIAR 18 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3 E7EPN9 PRRC2C Protein PRRC2C 1 DQMEGS(1)PNSSESFEHIAR 102.61 0.00031426 8975400.0 9923.1 8304.6 15114.0 21170.0 22338.0 19447.0 15734.0 23918.0 13195.0 13628.0 True False 13078.439386697908 10988.899544695749 14913.578484687838 16289.583573239564 19236.75428194701 18230.976015760345 17134.2955192032 20222.022680962302 13892.460761873606 13150.887868040367 0.9944909817443942 0.8356013415186408 1.1340358639154098 1.238667969546523 1.4627722838924568 1.386292408443824 1.3029002825614089 1.537692578925138 1.0563895686188176 1.0 13.682872584358112 -5.572369197884987 2.382759486141027 1.3221628210741065 0.9153739448376198 0.4350638692929122 0.16287986377488972 0.23114341791082457 2.62226689936575 0.044388908561554745 0.09892877141158972 2.6768917060746345e-06 5.572369197884987 -0.40678887623648674 DQMEGS(ph)PNSSESFEHIAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DQMEGSPNSSESFEHIAR 18 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3 E7EPN9 PRRC2C Protein PRRC2C 1 DQMEGS(0.6)PNS(0.315)S(0.085)ESFEHIAR;DQMEGS(0.999)PNS(0.001)SESFEHIAR 112.47 0.00012324 15658600.0 47893.0 47717.0 73528.0 73201.0 85498.0 75996.0 68783.0 57910.0 65224.0 43775.0 True False 56000.3389701322 52454.028409333136 75281.18637649278 69099.78529084387 68745.28065252834 72010.63597668792 62267.37629420419 56389.92386071688 66177.77760831495 51711.06097729068 1.082947011950213 1.0143676694695691 1.455804328005436 1.3362670187948682 1.3294115292416524 1.392557696859323 1.204140373788683 1.0904808912252053 1.2797605842467135 1.0 15.65818528504708 -9.042124755835548 0.7414334133264354 1.000008504915214 1.2608032001408156 0.2147611104441668 0.13754109828143424 2.9367657982109914 2.6097265932365974 0.1657774195514934 0.053544551141065676 9.075597862635203e-10 9.042124755835548 0.2607946952256015 DQMEGS(ph)PNSSESFEHIAR ddPTM_PC-9_Lapatinib_30min_R1 2 DQMEGSPNSSESFEHIAR 18 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3 E7EPN9 PRRC2C Protein PRRC2C 1 DQMEGS(0.983)PNS(0.013)S(0.002)ES(0.002)FEHIAR;DQMEGS(0.836)PNS(0.161)S(0.002)ESFEHIAR 118.05 5.8681e-05 7445900.0 26992.0 19694.9 31951.0 19254.0 23679.0 29322.0 22396.5 25007.0 26849.0 18229.3 True False 26607.089130273445 19649.297669101044 29324.112114426694 20670.00338946114 22286.247774705185 28067.966412920476 23556.081183083872 26168.916512541804 23824.98288749591 21380.210215984574 1.2444727559498492 0.9190413691260416 1.3715539659429068 0.9667820466053014 1.042377392437574 1.3128012367219808 1.1017703261623004 1.2239784477412214 1.1143474571491134 1.0 14.383988417643751 DQMEGSPNS(ph)SESFEHIAR ddPTM_PC-9_AZD4547_30min_R2 1 DQMEGSPNSSESFEHIAR 18 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3 E7EPN9 PRRC2C Protein PRRC2C 1 DQMEGS(0.148)PNS(0.639)S(0.201)ES(0.012)FEHIAR 117.6 7.5113e-05 10562000.0 7266.0 7286.4 15308.0 21912.0 20120.0 12976.0 13316.0 23553.0 13104.0 15084.0 True False 9576.436857811268 9641.586306681971 15105.005917930492 16860.52693702528 17326.685296480173 12164.608668715286 14501.09820348988 19913.425044096715 13796.650687653786 14555.913751212274 0.6579069525617177 0.6623827587518497 1.0377229609973806 1.1583283073260218 1.1903536660511702 0.8357159074058246 0.9962341390132359 1.368064237289002 0.9478381724063696 1.0 13.82931778740343 -5.2798106673849245 4.674472160357787 1.0792518321645963 0.6536871887068036 0.579501175416974 0.13859711051891946 0.1246107112298662 7.479235251333912 0.03722630825403722 0.08927807264777313 5.250363022799098e-06 5.2798106673849245 -0.42556464345779266 DQMHSHRK ddPTM_PC-9_AZD4547_30min_R2 1 DQMHSHRK 8 1 A6NFQ7 A6NFQ7 DPRX Divergent paired-related homeobox 0 84.743 0.032327 5764200.0 15316.0 11960.0 22577.0 32977.0 24901.0 21101.0 13311.0 26694.0 16876.0 15428.0 False True 20186.169407409496 15825.836109452714 22277.61422845026 25374.662139571148 21443.925972547357 19781.55113429109 14495.653213176165 22569.05566709623 17768.030906963162 14887.870415917725 1.3558802463666642 1.0630020054803904 1.4963600304199056 1.704384940940997 1.4403622125579536 1.3287025331132094 0.97365525143729 1.5159357944817937 1.1934568484667925 1.0 13.861849782890527 -7.0076670783137605 23.38355608074322 1.204816965869554 1.4106390733346665 0.23361880822216197 0.20265190566154065 284.3336775221192 867182.2925097647 0.07755560278377173 0.06542073033524373 9.825008203943644e-08 7.0076670783137605 0.20582210746511254 DQMPPS(ph)YLLERY(ph)AKRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DQMPPSYLLERYAKRK 16 3 A0A286YEQ6;A0A286YFD1;A0A286YFJ1;A0AVI2-4;A0AVI2-2;A0AVI2 A0A286YEQ6 FER1L5 Fer-1-like protein 5 2 DQMPPS(0.539)Y(0.47)LLERY(0.992)AKRK 54.598 0.03977 0.0 8970.3 7776.0 8806.9 9176.4 12038.0 8811.1 9518.5 9039.9 9000.7 7086.7 True False 10488.794618499083 8547.949890206308 9016.889896354245 8662.276058290201 9679.240315506057 8349.030404944939 8616.838772027717 8802.612203565777 9132.318209848536 8371.462611713661 1.2529225901126013 1.0210820123888147 1.0770985088958622 1.0347386663555809 1.1562185444109259 0.9973203957529077 1.0293110262441734 1.0515023015510856 1.0908868179223852 1.0 13.031263988479889 -4.755684404817606 24.99989910696263 1.0537707539517602 1.252922909789461 0.6409994271273978 0.04530947091101068 117.30134961552795 509511.16342422063 0.010898511472505175 0.09430912216908414 1.755155483276207e-05 4.755684404817606 0.19915215583770074 DQNTVETLQR ddPTM_PC-9_Lapatinib_30min_R1 1 DQNTVETLQR 10 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 103.31 0.014069 0.0 7598.7 14911.0 14273.0 8916.5 13410.0 15996.0 9350.2 10227.0 14396.0 10076.0 False True 7490.34114456908 14876.474495629105 13099.529035373283 9572.249154572046 12621.250165074383 15311.888368497233 9834.307605120037 10702.183755499063 12774.570883399421 11817.623174573942 0.6338280578014054 1.2588381162496698 1.1084740850053003 0.8099978323193701 1.0680024213523303 1.2956825702008619 0.8321730571236116 0.905612202843395 1.0809763261773644 1.0 13.528652281472235 -1.5233590757245816 0.004585501806655234 1.4443554984490345 0.545065879166379 0.0016712762833762662 0.1959551466293309 2114790.732855035 755.9560977599443 69276.24960331245 79290.41482969404 0.029966838290215608 1.5233590757245816 -0.8992896192826555 DQPAFTPS(ph)GILTPHALGSR ddPTM_PC-9_Lapatinib_30min_R1 1 DQPAFTPSGILTPHALGSR 19 0 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 DQPAFT(0.001)PS(0.852)GILT(0.147)PHALGSR 161.46 2.4413e-06 9411000.0 45722.0 45203.0 69707.0 44550.0 42344.0 59167.0 38631.0 38917.0 49706.0 35046.0 True False 45069.9958956121 45098.33523076404 63975.959536801405 47826.355614443375 39853.40917150709 56636.565335013496 40631.124157065315 40725.22589349338 44107.5868526154 41103.654404140354 1.096496079216553 1.0971855394497794 1.5564542974153932 1.1635548300451322 0.9695831124809349 1.3778961057367327 0.9885039358683533 0.9907933122703353 1.0730818826700834 1.0 15.3269790449006 -7.295174894468186 24.982083406465474 1.0123275093137918 1.207740374605606 0.2808048158985419 0.15449843009865988 913.4829279096373 676455.8248006724 0.06658220341769339 0.04489222637733159 5.067865794582111e-08 7.295174894468186 0.19541286529181412 DQPAFTPSGILT(ph)PHALGSR ddPTM_PC-9_AZD4547_30min_R2 4 DQPAFTPSGILTPHALGSR 19 0 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 DQPAFT(0.001)PS(0.068)GILT(0.926)PHALGS(0.006)R;DQPAFTPS(0.011)GILT(0.989)PHALGSR;DQPAFTPS(0.025)GILT(0.975)PHALGSR;DQPAFT(0.006)PS(0.262)GILT(0.731)PHALGS(0.001)R 115.81 0.00014996 30403300.0 46525.6 41344.1 63332.0 88728.0 82224.0 77038.0 59622.0 84147.0 60601.0 72135.0 True False 61319.77300740213 54707.77179705891 62492.17629960628 68273.13043393483 70808.61688955197 72220.8016816034 64928.24249688149 71144.01465569584 63804.245140606465 69609.57560618503 0.8809100252861429 0.7859230762527153 0.8977525829658076 0.9808008429786856 1.0172252347888242 1.0375124550419808 0.9327487192884482 1.0220435053101296 0.9166015535215712 1.0 16.086998158745985 -5.614074051570018 3.155215918658646 0.9892460365193534 0.833623701337135 0.6890823185946353 0.04193989821417476 0.12571905597606622 2.487234218197246 0.011349139289938658 0.021982620133611953 2.431789329222477e-06 5.614074051570018 -0.15562233518221835 DQPAFTPSGILT(ph)PHALGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DQPAFTPSGILTPHALGSR 19 0 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 DQPAFTPSGILT(1)PHALGSR;DQPAFTPSGILT(1)PHALGSR;DQPAFT(0.023)PS(0.066)GILT(0.894)PHALGS(0.018)R;DQPAFTPSGILT(0.997)PHALGS(0.003)R 111.49 0.00026372 24371500.0 105861.0 123703.0 137351.0 141785.0 157518.0 137821.0 149145.0 126852.0 115629.0 97527.0 True False 123781.1764499439 135983.41631535374 140625.96874656816 133841.24612317176 126653.47865242402 130593.42413999586 135016.90588370792 123522.2694108038 117319.85537642348 115207.87307669262 1.0744159504406798 1.1803309329808656 1.2206281132623202 1.1617369763789938 1.0993474253978475 1.1335460038660834 1.1719416588294156 1.0721686470904326 1.0183319268321613 1.0 16.81387978549295 -8.016597717689484 2.5645051953065092 1.0076921136617083 1.150991460614864 0.6705605338381418 0.039542025804683356 0.18303538607075298 2.265882573725854 0.03326132555660153 0.011468222172068391 9.625034221658524e-09 8.016597717689484 0.1432993469531556 DQPAFTPSGILT(ph)PHALGSR ddPTM_PC-9_Lapatinib_30min_R1 3 DQPAFTPSGILTPHALGSR 19 0 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 DQPAFTPS(0.001)GILT(0.999)PHALGSR;DQPAFTPSGILT(0.985)PHALGS(0.015)R;DQPAFTPSGILT(0.996)PHALGS(0.004)R 117.11 0.0001339 14563900.0 56923.0 57867.0 75346.0 58980.0 64852.0 65097.0 56503.0 55695.2 65989.0 47176.9 True False 56111.26758160028 57733.01251683787 69151.34272397094 63317.58595151224 61037.532863937675 62312.95305851868 59428.44886869767 58283.002317323844 58556.623925023894 55331.36430573217 1.014095139088904 1.0434048254772004 1.2497675340495276 1.1443344429689533 1.1031271979247828 1.1261777807286641 1.0740463318476507 1.0533447538955025 1.058289898681526 1.0 15.755809876307739 -7.990006338732878 0.9489518693942439 1.0103861755694687 1.118103532503636 0.2569472616239875 0.06002163653691571 0.8005130872249603 1.357378100445765 0.05966209857617119 0.02263823491138935 1.0232780569457015e-08 7.990006338732878 0.10771735693416717 DQPDGSSLS(ph)PAQSPSQSQPPAASSLREPGLESK ddPTM_PC-9_AZD4547_30min_R2 2 DQPDGSSLSPAQSPSQSQPPAASSLREPGLESK 33 1 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 DQPDGS(0.068)S(0.049)LS(0.56)PAQS(0.119)PS(0.119)QS(0.086)QPPAASSLREPGLESK;DQPDGS(0.017)S(0.064)LS(0.901)PAQS(0.01)PS(0.002)QS(0.006)QPPAASSLREPGLESK 100.24 3.2479e-16 16471000.0 46999.0 41623.0 59508.0 65177.0 65735.0 61362.0 60272.0 65366.0 53765.0 61243.0 True False 61943.70436007046 55076.820767872145 58718.88503816353 50151.44962461194 56608.82991869407 57525.02443971236 65636.0912376646 55265.18666125015 56606.90813657704 59098.9012109184 1.0481363120271767 0.9319432280358001 0.993569826765499 0.8486020653011154 0.957866030650257 0.9733687642416732 1.1106144089450258 0.9351305274528525 0.9578335125817709 1.0 15.850843687070778 -7.005497146368128 24.536421326509643 1.002132067763237 0.952285101750664 0.09849593142454705 0.06349135856832469 439.32786696643245 1960941.008039423 0.02314954929461462 0.019784630364992492 9.874221238099275e-08 7.005497146368128 -0.04984696601257299 DQPDGSSLS(ph)PAQSPSQSQPPAASSLREPGLESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DQPDGSSLSPAQSPSQSQPPAASSLREPGLESK 33 1 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 DQPDGS(0.051)S(0.042)LS(0.696)PAQS(0.167)PS(0.035)QS(0.009)QPPAASSLREPGLESK 65.244 1.7622000000000002e-05 6206100.0 12600.0 15507.0 17324.0 15968.0 20667.0 15663.0 22288.0 14964.0 14234.0 13098.0 True False 14732.931138656288 17046.43247780726 17737.06986163586 15073.364728954482 16617.449709300847 14841.604706864364 20176.719288853696 14571.21085566858 14442.145321917622 15472.563716289054 0.9521971541888625 1.1017199728743907 1.1463562333217476 0.9741995577039178 1.0739945890031457 0.9592207845451989 1.304032069850987 0.9417450865190778 0.9334035126133209 1.0 13.917424642550746 DQPDGSSLS(ph)PAQSPSQSQPPAASSLREPGLESK ddPTM_PC-9_Lapatinib_30min_R1 2 DQPDGSSLSPAQSPSQSQPPAASSLREPGLESK 33 1 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 DQPDGS(0.038)S(0.094)LS(0.836)PAQS(0.021)PS(0.006)QS(0.004)QPPAASSLREPGLESK;DQPDGS(0.03)S(0.034)LS(0.336)PAQS(0.265)PS(0.265)QS(0.071)QPPAASSLREPGLESK 91.265 3.0448e-12 19265000.0 38863.0 37471.0 36808.0 35352.0 38910.0 36334.0 32633.0 31121.0 34289.0 32874.0 True False 38308.80649339867 37384.23820171138 33781.788322988854 37951.904010814906 36621.39030000329 34780.07951869085 34322.57706550469 32566.995272796143 30427.011740822658 38556.22709814844 0.9935828626561427 0.9696031229027244 0.8761694508384907 0.9843261871605027 0.949817787066669 0.9020612787178306 0.8901954275280461 0.8446623988880926 0.7891594699701266 1.0 15.23467626376513 -7.01594163159116 1.93528832087452 0.8660088134789679 0.9534073554024267 0.25747666892268906 0.05795075519786127 0.4222327876695103 3.17099768320106 0.025741496540648837 0.019640917588159286 9.639585692420905e-08 7.01594163159116 0.08739854192345886 DQPKS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DQPKSR 6 1 Q96D59 Q96D59 RNF183 RING finger protein 183 1 DQPKS(1)R 76.847 0.021733000000000002 0.0 5312.8 6355.6 7436.4 7943.5 7908.3 9344.4 7802.8 8212.9 6693.8 8322.9 True False 6212.152107416911 6986.541965302887 7613.711978704047 7498.451448174469 6358.725385206558 8854.36321412394 7063.662296620044 7997.320077286856 6791.684161574554 9831.775885959845 0.6318443564491847 0.7106083424134939 0.7743984471388045 0.7626751804709612 0.6467524747270799 0.9005863555909885 0.7184523303371089 0.8134156199295935 0.6907891555251316 1.0 13.263236314703478 -14.522878745280336 0.18734624053655505 2.060772775006455 0.6967867530720792 0.5276344797608419 0.07478246679003872 108.13496653326295 1.0505803863191816 42.94328277160372 0.20392785867427615 3.0000000000000132e-15 14.522878745280336 -1.3639860219343758 DQPPFGDSDDSVEADKS(ph)SPGIHLER ddPTM_PC-9_Lapatinib_30min_R1 1 DQPPFGDSDDSVEADKSSPGIHLER 25 1 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 DQPPFGDSDDSVEADKS(0.5)S(0.5)PGIHLER 57.152 0.0021812 3565500.0 12747.0 12072.0 15465.0 11644.0 15081.0 14922.0 13595.0 13760.0 13432.0 9796.7 True False 12565.225442486499 12044.048025701464 14193.527396626354 12500.338603245313 14193.965230386784 14283.820844880955 14298.882579154111 14399.339833349659 11919.146714769451 11490.046541717802 1.0935748081493806 1.0482157737109423 1.2352889385689445 1.0879275865297295 1.2353270440508362 1.243147344357534 1.2444581949462128 1.2532011755625934 1.0373453816304121 1.0 13.48809702134283 -5.251226325772032 24.883894129808127 1.1812195840201272 1.0708952800004659 0.13851360327938111 0.09063061165433642 1046.649936544077 2550126.1853797776 0.02223683047356863 0.057417613402068225 5.607556708325669e-06 5.251226325772032 -0.11032430401966131 DQQEAALVDMVNDGVEDLR ddPTM_PC-9_AZD4547_30min_R2 8 DQQEAALVDMVNDGVEDLR 19 0 P09211;A8MX94 P09211 GSTP1 Glutathione S-transferase P 0 ;;;;;;; 185.02 7.7638e-39 25884900.0 65340.399999999994 52484.74 81918.1 93804.1 92696.7 83871.2 79631.59999999999 105042.3 75540.0 84064.4 False True 86117.28803525068 69449.40580996971 80831.81246966438 72179.01400389806 79827.36326651262 78626.72060539082 86718.65813314979 88810.42616692239 79532.89018203346 81121.33094321194 1.061586231807958 0.856117682026038 0.9964310438428304 0.8897661461499707 0.9840489836439549 0.9692484047190073 1.0689994496497621 1.094785121672783 0.980418950937942 1.0 16.307793702125167 -7.129951911201668 4.2094444726135825 1.0436032410480216 0.9523434495783218 0.26850564713906133 0.06108822721310851 0.2695655761738238 7.9246188360769745 0.022807672483765497 0.01746982515068984 7.413923300538702e-08 7.129951911201668 -0.09125979146969976 DQQEAALVDMVNDGVEDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 DQQEAALVDMVNDGVEDLR 19 0 P09211;A8MX94 P09211 GSTP1 Glutathione S-transferase P 0 ;;;; 170.11 2.1744e-07 15729400.0 70019.3 76230.7 81723.6 86918.6 102609.6 82411.2 90728.5 71460.5 72614.3 66513.8 False True 81872.1845457868 83798.38010485459 83672.20056247909 82048.83263590331 82503.98546917689 78089.41159537388 82134.0396625432 69584.73759365844 73676.14676474096 78572.22541704896 1.0419990538796906 1.0665140214632591 1.0649081163014062 1.0442472794985895 1.050040074991624 0.9938551591340021 1.0453317215668603 0.8856149513942573 0.9376869036568534 1.0 16.26173180228154 -7.745731017699248 24.998180109573596 0.9337382049417738 1.0438558277521293 0.6827929032490867 0.03197304216871517 118.7938591277055 189048.35036325402 0.014987548969941297 0.00861562350464571 1.7958455477258078e-08 7.745731017699248 0.11011762281035542 DQQEAALVDMVNDGVEDLR ddPTM_PC-9_Lapatinib_30min_R1 8 DQQEAALVDMVNDGVEDLR 19 0 P09211;A8MX94 P09211 GSTP1 Glutathione S-transferase P 0 ;;;;;;; 237.06 5.457599999999999e-43 31863100.0 65997.5 69516.84 82897.94 74226.10999999999 82681.44 76075.6 69155.22 68816.47 88046.5 68082.5 False True 65056.363547540765 69355.87802808193 76082.39136850231 79684.9457404443 77818.28025716539 72822.02392888532 72735.73891250986 72013.93442307519 78129.77599925167 79850.46941077108 0.8147273776547802 0.8685719512968383 0.9528108216510937 0.9979270795582266 0.9745500662851261 0.9119799102779265 0.9108993278215906 0.9018598757712648 0.9784510545245798 1.0 16.285013268270504 -5.0748890548491286 2.902499918398015 0.9494270630135516 0.818580899148622 0.6442669292327852 0.03420814493786209 0.19069443823718832 2.962831770608102 0.009811941351190337 0.04165983723256292 8.416101124525602e-06 5.0748890548491286 -0.13084616386492964 DQQGLSSTST(ph)LT(ph)VAVK ddPTM_PC-9_AZD4547_30min_R2 1 DQQGLSSTSTLTVAVK 16 0 A0A087X0U9;Q5VV43-4;Q5VV43-3;Q5VV43-2;Q5VV43 A0A087X0U9 KIAA0319 Dyslexia-associated protein KIAA0319 2 DQQGLS(0.002)S(0.016)T(0.019)S(0.508)T(0.597)LT(0.858)VAVK 64.331 0.033979 75118000.0 30567.0 20504.0 30183.0 59200.0 45527.0 33340.0 34207.0 48485.0 30927.0 43177.0 True False 40286.670166902986 27131.517022426317 29782.753698778128 45552.35463088247 39206.3619032233 31255.244529513533 37251.356732260334 40992.75732446096 32561.73808127812 41665.38637205597 0.9669097943112402 0.6511764172820155 0.7148080527282172 1.0932901047434762 0.9409815992854471 0.7501489185871494 0.8940600334200663 0.9838564068123913 0.7815057273323773 1.0 15.346561738129484 -9.128436189058268 0.021543779312685436 1.8491102220837008 2.132088825426082e-06 0.07728527461682044 0.1318151177138656 1388.720942187841 11.692526566790097 530.1567109229894 471.3839319464334 7.439843685921584e-10 9.128436189058268 -1.8491080899948753 DQQNLPYGVT(ph)PASPSGHSQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DQQNLPYGVTPASPSGHSQGR 21 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 DQQNLPYGVT(0.539)PAS(0.451)PS(0.009)GHS(0.001)QGR 145.73 0.00037334 6002200.0 6831.9 8398.3 17993.0 17562.0 26344.0 25027.0 20094.0 23202.0 21436.0 15110.0 True False 7988.40573382428 9232.027721568886 18422.021358832488 16578.05807677222 21182.082311986345 23714.540062484466 18190.550852038148 22592.972084551082 21749.46094707225 17849.323389305817 0.44754669740649256 0.5172200379931562 1.0320851360601038 0.9287779550626968 1.186716260890724 1.3285960226757232 1.0191171091077196 1.2657607009399223 1.2185033837250743 1.0 14.12358176689099 -5.239325112182009 1.1599696446997896 1.175918184719033 0.30069389451088957 0.8258541819824092 0.11844850389399782 0.3039058543169989 0.5715030636986664 0.03754920419987717 0.26675824823797056 5.763348584733043e-06 5.239325112182009 -0.8752242902081434 down DQQNLPYGVTPAS(ph)PSGHSQGR ddPTM_PC-9_AZD4547_30min_R2 3 DQQNLPYGVTPASPSGHSQGR 21 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 DQQNLPYGVT(0.077)PAS(0.865)PS(0.05)GHS(0.007)QGR;DQQNLPYGVT(0.019)PAS(0.914)PS(0.063)GHS(0.004)QGR;DQQNLPYGVTPAS(0.997)PS(0.003)GHSQGR 265.63 1.2487999999999997e-86 28412400.0 28737.6 32157.699999999997 84094.0 135663.0 105930.0 100781.0 69421.0 129389.0 82976.0 93828.0 True False 37875.55902078682 42552.04764690198 82978.85861395655 104387.99132245622 91223.44798489778 94479.14813823937 75599.3345137032 109394.90311343073 87361.94196113858 90543.11027902045 0.4183151970820124 0.4699645010622263 0.916456904984226 1.1529092716250962 1.0075139643842672 1.0434714231385416 0.8349540266590573 1.20820792190942 0.9648657053189506 1.0 16.46631724552384 -5.299044359692635 3.3714639356856657 1.0308816387394646 0.42376613777966365 0.8531227191646885 0.0959440114474067 0.0767147007624669 1.786668593010656 0.02488235228740461 0.06502910795156149 5.022912818825659e-06 5.299044359692635 -0.6071155009598009 down DQQNLPYGVTPAS(ph)PSGHSQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DQQNLPYGVTPASPSGHSQGR 21 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 DQQNLPYGVTPAS(0.963)PS(0.032)GHS(0.005)QGR;DQQNLPYGVTPAS(0.98)PS(0.019)GHS(0.001)QGR;DQQNLPYGVT(0.093)PAS(0.897)PS(0.01)GHSQGR 160.47 5.3507e-06 25528300.0 50703.0 58018.0 108226.0 98892.0 135686.0 121912.0 103105.0 107993.0 112489.0 78279.0 True False 59286.01647010233 63777.64361239579 110806.51828939046 93351.40185218968 109099.30233010113 115518.72010618976 93338.14798444252 105158.29817804148 114133.93881671998 92470.36304377684 0.6411353272403121 0.6897090214970012 1.198292238097227 1.0095277965762472 1.179829934034669 1.2492512876963777 1.009384465596343 1.1372108286009215 1.2342758810483665 1.0 16.496703432303704 -5.254016823480192 23.651770227398593 1.1299472039507874 0.6654219926154213 0.8111394656158073 0.08912475460586929 101.92768727223908 324784.8938290372 0.022179303026151863 0.05605161107550072 5.5716416536998215e-06 5.254016823480192 -0.46452521133536606 DQQNLPYGVTPAS(ph)PSGHSQGR ddPTM_PC-9_Lapatinib_30min_R1 3 DQQNLPYGVTPASPSGHSQGR 21 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 DQQNLPYGVT(0.01)PAS(0.982)PS(0.005)GHS(0.003)QGR;DQQNLPYGVTPAS(0.923)PS(0.05)GHS(0.027)QGR;DQQNLPYGVT(0.002)PAS(0.991)PS(0.007)GHSQGR 162.87 4.8022e-07 59228100.0 43925.5 38532.1 62534.0 40350.3 50756.3 48269.5 42182.2 50270.3 65691.9 42200.7 True False 43299.11431504985 38442.881289855184 57392.69590822065 43317.79566665488 47770.914224725224 46205.126006700266 44366.18791691024 52606.041658752714 58292.98645562559 49495.03476610188 0.8748173330853888 0.7767017736531405 1.1595647155202669 0.8751947719879638 0.9651657878507548 0.9335305293763566 0.8963765381026809 1.0628549289308005 1.1777542278957898 1.0 15.59499618398182 -7.855415692486742 5.158161849337981 1.0976546755263548 0.9292264935344968 0.3310140747048431 0.10042597841869709 0.2348825821109241 10.038005361531257 0.056019622147233786 0.026264028066919867 1.3950324423403893e-08 7.855415692486742 -0.16842818199185794 DQS(ph)CNHKEITSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DQSCNHKEITSTK 13 1 A2T115;P59103-3;P59103 A2T115 DAOA D-amino acid oxidase activator 1 DQS(0.983)CNHKEIT(0.006)S(0.006)T(0.006)K 51.841 0.045394 5630400.0 25382.0 21032.0 24544.0 24951.0 33167.0 27107.0 25947.0 30292.0 27361.0 17122.0 True False 29678.671282648724 23119.917964354318 25129.22204363834 23553.07636223344 26668.164441301662 25685.461200853748 23489.11231998775 29496.867097027025 27761.102863073484 20226.083062322577 1.4673464551292463 1.1430744100632324 1.2424166343136105 1.1644902421125933 1.318503654866299 1.2699177157390882 1.1613277888561424 1.4583578543674722 1.372539743732549 1.0 14.303929337423789 DQS(ph)CNHKEITSTK ddPTM_PC-9_Lapatinib_30min_R1 1 DQSCNHKEITSTK 13 1 A2T115;P59103-3;P59103 A2T115 DAOA D-amino acid oxidase activator 1 DQS(0.993)CNHKEIT(0.003)S(0.003)T(0.001)K 59.57 0.028727 8173100.0 21478.0 24225.0 14017.0 20562.0 21220.0 17194.0 20507.0 14494.0 14738.0 17355.0 True False 21171.719781417185 24168.908500879563 12864.576367184709 22074.19807282121 19971.88132012517 16458.65270117163 21568.75211847836 15167.444152948401 13078.05124197976 20354.788625916113 1.0401345929213404 1.1873819446155898 0.6320171927899698 1.0844719873296014 0.9811883428107222 0.808588730821609 1.0596401915476836 0.7451536064411357 0.6425048907326176 1.0 14.313080619454002 -7.774575340063283 24.99796010122028 0.7703718547029237 0.9643814304160524 0.1788881126492745 0.16843355235034838 370.00634768938755 704117.9334697657 0.08888117823470248 0.043103767848763234 1.680446381781346e-08 7.774575340063283 0.1940095757131287 DQS(ph)IMDVLK ddPTM_PC-9_Lapatinib_30min_R1 1 DQSIMDVLK 9 0 Q6ZT12;Q6ZT12-4 Q6ZT12 UBR3 E3 ubiquitin-protein ligase UBR3 1 DQS(1)IMDVLK 75.73899999999999 0.022484 1344700.0 5691.8 16092.0 14322.0 13328.0 16382.0 9318.3 13455.0 14550.0 18230.0 15058.0 True False 5610.633888251717 16054.739962689535 13144.500444518762 14308.185580904646 15418.442968251193 8919.778031018244 14151.634064179385 15226.046117386453 16176.745429589562 17660.755236476212 0.31768935207615656 0.9090630467223937 0.7442773691450263 0.8101683868735564 0.8730341801242006 0.5050620945470946 0.8013040141653087 0.8621401470951167 0.9159713281218234 1.0 14.108259418607263 -3.572045570123143 0.09284189193131703 1.1655971230228426 1.4106037859249187e-14 0.3202269914075999 0.16293393070807194 136.33315341611817 1.4410884264729025 3.459270260910162 20.94204506335593 0.0002678887216883296 3.572045570123143 -1.1655971230228284 DQS(ph)PFSK ddPTM_PC-9_AZD4547_30min_R2 4 DQSPFSK 7 0 Q13427;E9PG73 Q13427 PPIG Peptidyl-prolyl cis-trans isomerase G 1 DQS(0.998)PFS(0.002)K;DQS(0.998)PFS(0.002)K;DQS(0.983)PFS(0.017)K;DQS(0.771)PFS(0.229)K 117.53 0.0073208 528143000.0 1163400.0 1201780.0 1380070.0 1385180.0 1347860.0 1374200.0 1444020.0 1591650.0 1370770.0 1405680.0 True False 1533336.9997767177 1590231.8829112127 1361769.3700782794 1065848.151817665 1160732.9047571465 1288271.056762374 1572534.9825625902 1345697.0649784098 1443226.10371758 1356467.5710556908 1.1303897214316563 1.1723331370713062 1.003908533558574 0.7857527703284148 0.8557026570519405 0.9497249210018034 1.1592868241875784 0.992059886791913 1.063959164607502 1.0 20.3714231269798 -5.329562847247597 5.148431668835057 0.9690118870155817 1.151259603837084 0.34192686091030977 0.09741808564047649 0.2409752728320775 12.304614561376315 0.028898905667126114 0.06320305170572602 4.682061918212935e-06 5.329562847247597 0.1822477168215022 DQS(ph)PFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DQSPFSK 7 0 Q13427;E9PG73 Q13427 PPIG Peptidyl-prolyl cis-trans isomerase G 1 DQS(0.737)PFS(0.263)K;DQS(0.999)PFS(0.001)K;DQS(0.998)PFS(0.002)K;DQS(0.751)PFS(0.249)K;DQS(0.637)PFS(0.363)K;DQS(1)PFSK 140.17 0.0026899000000000003 450894000.0 1037330.0 1105790.0 1061920.0 1099520.0 1195460.0 951860.0 1137220.0 885660.0 918610.0 805780.0 True False 1212929.4807986 1215565.5232884851 1087240.2001540244 1037917.4590919339 961218.194681415 901942.785946236 1029494.2888401912 862412.3634343357 932042.933410621 951861.5354490309 1.2742709266284333 1.277040281615177 1.1422251658074722 1.0904080272581946 1.0098298532758445 0.9475567110932303 1.0815588722728855 0.9060271177230641 0.9791791124020358 1.0 19.86039219854805 -5.628224640745222 1.048488475284921 0.9789490363190277 1.309651648671863 0.8703318799741522 0.04395524324198938 0.21324122660816433 0.41915291267804133 0.015996534036455286 0.05786003405130973 2.3538314392130902e-06 5.628224640745222 0.33070261235283527 DQS(ph)PFSK ddPTM_PC-9_Lapatinib_30min_R1 3 DQSPFSK 7 0 Q13427;E9PG73 Q13427 PPIG Peptidyl-prolyl cis-trans isomerase G 1 DQS(0.926)PFS(0.074)K;DQS(0.998)PFS(0.002)K;DQS(0.788)PFS(0.212)K 128.28 0.0044733 572702000.0 973250.0 1219510.0 1301550.0 1136100.0 1300030.0 1297390.0 1236820.0 1321440.0 1278450.0 1089100.0 True False 959371.2765278096 1216686.2995214737 1194541.5831282942 1219652.5839184984 1223564.7913573205 1241903.6540638052 1300856.4877932607 1382838.9265538927 1134457.4983246715 1277349.483865469 0.7510640499298553 0.952508545930266 0.9351720873706509 0.9548307642694853 0.9578935184242708 0.9722504841083907 1.0184029541051332 1.0825846364060017 0.8881339935971299 1.0 20.284721870918226 -4.070005925513363 1.1740531482234955 0.9840308151670124 2.2638132350842468e-23 0.6456780651265206 0.04942756186551456 4.447297532001005 1.5527286225942878 0.014860556489308152 8.047207673103593 8.511264253552806e-05 4.070005925513363 -0.9840308151670124 DQT(ph)ASAPATPLVNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DQTASAPATPLVNK 14 0 A0A0X1KG75;A0A590PXD8;A0A0D9SG04;Q53SF7;Q53SF7-3;Q53SF7-2;A0A0B4J1Z0 A0A0X1KG75 COBLL1 Cordon-bleu protein-like 1 1 DQT(0.484)AS(0.224)APAT(0.292)PLVNK 136.57 0.00014052 6196800.0 22563.0 23064.0 27679.0 36337.0 34377.0 28191.0 34281.0 23397.0 23984.0 19922.0 True False 26382.470260436647 25353.64149533414 28338.972333192043 34301.15569614349 27641.07362735935 26712.614332580804 31033.65550705284 22782.85354117064 24334.720626729828 23533.700897534767 1.1210506318281752 1.0773333784483519 1.2041868151796151 1.4575334260212618 1.1745315259893885 1.1350791976530576 1.318689977499617 0.9680948032936553 1.034037133924778 1.0 14.522440595422884 -7.774133727768194 24.992824728330458 1.0007993960871786 1.2120722797378292 0.4670081515094754 0.1037460720951888 226.84207279635393 446603.3959338584 0.06006236635361214 0.029151435449645484 1.6821560125673265e-08 7.774133727768194 0.21127288365065056 DQTAS(ph)APATPLVNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DQTASAPATPLVNK 14 0 A0A0X1KG75;A0A590PXD8;A0A0D9SG04;Q53SF7;Q53SF7-3;Q53SF7-2;A0A0B4J1Z0 A0A0X1KG75 COBLL1 Cordon-bleu protein-like 1 1 DQT(0.002)AS(0.651)APAT(0.347)PLVNK 82.837 0.0087739 7401100.0 27849.0 26440.0 30036.0 34104.0 47218.0 30389.0 38929.0 37756.0 32031.0 29607.0 True False 32563.285657177705 29064.788464127432 30752.172152164327 32193.263446659803 37965.97185724913 28795.347343222966 35241.36329844694 36764.94500578876 32499.392778301488 34974.514731116964 0.931057540255334 0.831027640771478 0.8792737337054172 0.9204777734347613 1.0855324841282403 0.8233237134124876 1.0076298004241515 1.051192426497882 0.9292306992150101 1.0 15.094016419788144 -6.00923789193409 18.291007485167853 0.9808583717717277 0.879570285731366 0.3043724522213518 0.07033964692239407 15.857648017863252 31404.356432469485 0.019930001532645885 0.02771680402575491 9.78953600605015e-07 6.00923789193409 -0.10128808604036177 DQTAS(ph)APATPLVNK ddPTM_PC-9_Lapatinib_30min_R1 1 DQTASAPATPLVNK 14 0 A0A0X1KG75;A0A590PXD8;A0A0D9SG04;Q53SF7;Q53SF7-3;Q53SF7-2;A0A0B4J1Z0 A0A0X1KG75 COBLL1 Cordon-bleu protein-like 1 1 DQT(0.002)AS(0.93)APAT(0.068)PLVNK 88.561 0.005668100000000001 8836400.0 56708.0 49903.0 53588.0 44991.0 43603.0 51746.0 53661.0 57950.0 45614.0 29163.0 True False 55899.33352102644 49787.45266953115 49182.20149566199 48299.78822557625 41038.35726679629 49532.94420581757 56439.304014710455 60642.56855687598 40476.47098328574 34203.78569274513 1.6343025308126373 1.4556123441064428 1.4379169001194476 1.412118198244383 1.1998191555591702 1.4481713998203383 1.6500893942474222 1.7729782633312052 1.1833915504818255 1.0 15.061868391733494 -8.496305402244673 8.289468285794962 1.0000361564368188 1.4876315485918528 0.5600701865720632 0.14931215733981598 0.17950368607586747 50.040542749320444 0.15710024211343993 0.04060083156952011 3.1892943078461448e-09 8.496305402244673 0.487595392155034 DQTASAPAT(ph)PLVNK ddPTM_PC-9_AZD4547_30min_R2 2 DQTASAPATPLVNK 14 0 A0A0X1KG75;A0A590PXD8;A0A0D9SG04;Q53SF7;Q53SF7-3;Q53SF7-2;A0A0B4J1Z0 A0A0X1KG75 COBLL1 Cordon-bleu protein-like 1 1 DQT(0.001)AS(0.351)APAT(0.648)PLVNK;DQTAS(0.208)APAT(0.792)PLVNK 162.29 0.0011812 19843700.0 48645.0 64663.0 91155.0 128520.0 109072.0 103598.0 86869.0 119768.0 83194.0 99212.0 True False 64113.09812114357 85564.0501961154 89946.22514038111 98891.69961420624 93929.2355197658 97120.00068291978 94600.1727124483 101260.60759484461 87591.46499608282 95738.61807778267 0.66966809641074 0.8937255614719551 0.9394978426292352 1.0329342704096884 0.9811008076537429 1.0144286875335387 0.9881088176517292 1.057677765022424 0.9149021236646564 1.0 16.546813361429997 -4.344180110999853 1.1682037983601354 1.0001842155595946 0.1342583874218961 0.8723609560458576 0.037577836586473075 1.1373927952416583 0.6568664498423192 0.010575567524984465 1.5387057755746691 4.527097927524804e-05 4.344180110999853 -0.8659258281376985 DQTASAPAT(ph)PLVNK ddPTM_PC-9_Lapatinib_30min_R1 1 DQTASAPATPLVNK 14 0 A0A0X1KG75;A0A590PXD8;A0A0D9SG04;Q53SF7;Q53SF7-3;Q53SF7-2;A0A0B4J1Z0 A0A0X1KG75 COBLL1 Cordon-bleu protein-like 1 1 DQT(0.003)AS(0.241)APAT(0.756)PLVNK 97.76700000000001 0.0064064 8279000.0 55290.0 61447.0 60564.0 49104.0 54878.0 49620.0 64017.0 53631.0 53411.0 45058.0 True False 54501.55446105579 61304.72324679242 55584.66170380071 52715.27196614208 51650.18393429922 47497.86826986953 67331.48702241342 56122.892049591275 47395.29073723581 52846.215263988895 1.0313237038603007 1.1600589170019036 1.0518191591608241 0.9975221821053277 0.9773677012873107 0.898794133744448 1.2741023493558536 1.0620040010289102 0.896853076430858 1.0 15.689512532039254 -5.513896235055565 21.998340422431564 1.0223668911629358 1.0982532712117508 0.0852916981258055 0.10363771263115149 227.66215380097523 557540.9223711023 0.028752299321045498 0.053570906682561155 3.0626951087139547e-06 5.513896235055565 0.07588638004881498 DQTDFEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DQTDFEHR 8 0 F8VZI0;A0A2R8Y891;P08237-2;P08237;P08237-3 F8VZI0 PFKM ATP-dependent 6-phosphofructokinase, muscle type 0 65.347 0.043668 20645000.0 17370.0 17561.0 30441.0 24398.0 40713.0 28007.0 33387.0 32665.0 28138.0 25231.0 False True 20310.397926861886 19304.34002339417 31166.828888135373 23031.059159383243 32735.5799107159 26538.26361649429 30224.341659052312 31807.578361428376 28549.465018133906 29805.18057151389 0.6814385129501084 0.6476840486530777 1.0456849544445594 0.7727200009449039 1.0983184561546566 0.8903909692081539 1.0140633634657135 1.0671828773226177 0.9578692183941966 1.0 14.863275493299003 -5.255702644522575 24.815623206901947 0.9779059015691579 0.664561236969197 0.6677004400974706 0.08921342694852506 230.47531300656874 996967.9860878974 0.021911130791284143 0.05470887729203554 5.550055876120975e-06 5.255702644522575 -0.3133446645999609 DQTS(ph)PAVK ddPTM_PC-9_AZD4547_30min_R2 1 DQTSPAVK 8 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 DQT(0.044)S(0.956)PAVK 75.566 0.026189999999999998 15517000.0 136480.0 108510.0 134980.0 158900.0 125450.0 127530.0 112950.0 130210.0 113240.0 127100.0 True False 179877.80103964766 143583.73547129717 133190.0770056346 122268.0599805274 108033.43292462424 119555.52893967804 123002.33118685645 110089.0364281339 119225.63521595806 122650.26768622916 1.4665911818457764 1.1706760872191588 1.0859338468495559 0.9968837597103372 0.8808250887882404 0.9747677782940658 1.0028704666305985 0.8975849666286085 0.9720780677052235 1.0 16.90419085704145 -4.1978479523499415 0.8579335370435685 0.9508219343455409 2.434486472064948 0.9305288438608141 0.042521139104549 1.293289540297515 0.3652478344678909 0.015064177945897381 2.2958853926084637 6.340916695759764e-05 4.1978479523499415 1.4836645377194073 DQTS(ph)PAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DQTSPAVK 8 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 DQT(0.045)S(0.955)PAVK 70.41199999999999 0.03821 11941000.0 81727.0 82531.0 108850.0 119540.0 137800.0 151080.0 154310.0 153420.0 166300.0 128090.0 True False 95561.76691817147 90724.13225162239 111445.3968159236 112842.56135390878 110799.07920557694 143157.09883886017 139692.63969234616 149392.88756192697 168731.82289130948 151311.7030401178 0.6315556893364345 0.5995843707315116 0.7365286000804292 0.7457622846528298 0.7322571683447406 0.946107247242498 0.9232110728098074 0.9873187900232535 1.1151273794504382 1.0 17.207164049995363 -6.711400845003429 0.6689417324373816 1.0575300813477444 0.6166730265137603 0.9020303567876198 0.051772543492576525 0.21413813944106502 0.21144783352654783 0.038716206480562926 0.04278722045414096 1.9435653820638158e-07 6.711400845003429 -0.4408570548339841 DQVANS(ph)AFVER ddPTM_PC-9_AZD4547_30min_R2 1 DQVANSAFVER 11 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 DQVANS(1)AFVER 118.51 0.0010567999999999999 6895300.0 13055.0 14981.0 23960.0 24225.0 19702.0 26130.0 15078.0 24651.0 13798.0 19206.0 True False 17206.218439131033 19823.31528057786 23642.2747448141 18640.30052251905 16966.71738127496 24496.086969291788 16419.912790043585 20841.754373626623 14527.334110824713 18533.60378585143 0.9283795336267131 1.0695877342382272 1.2756436912103752 1.0057569341559505 0.9154570032530516 1.3217120238640325 0.8859535889387342 1.1245386819770713 0.7838375244600241 1.0 14.177855814528503 -8.250860069469462 24.939125282984456 0.8919187534585634 1.0685066199499047 0.18444790028681524 0.14623458773477688 977.4892608676645 2304297.423197228 0.09738250444188588 0.035954145723000895 5.61228775911924e-09 8.250860069469462 0.17658786649134128 DQVANS(ph)AFVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DQVANSAFVER 11 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 DQVANS(1)AFVER;DQVANS(1)AFVER 118.51 0.0010567999999999999 8112200.0 17268.4 21765.4 27550.0 23159.1 33510.9 26565.0 28453.4 19393.0 23421.2 21306.6 True False 20191.599053553346 23926.125069482576 28206.89648395681 21861.570709815234 26944.679705008468 25171.8846349902 25758.087967223164 18883.954298581964 23763.69074144281 25169.31791704721 0.8022306810260261 0.9506068121646388 1.1206857721341843 0.8685801809117905 1.0705367461213084 1.0001019780492841 1.0233923720982991 0.7502767600146939 0.9441531478827891 1.0 14.619378499861336 -10.172663484797734 5.732317235095022 1.000000000869518 0.9522315874314362 0.018593600860265735 0.10958094616373008 1.2552516709225148e-09 2.7844875764254907e-10 0.10711625454265734 0.025979507359929526 6.719493144698347e-11 10.172663484797734 -0.0477684134380818 DQVANS(ph)AFVER ddPTM_PC-9_Lapatinib_30min_R1 1 DQVANSAFVER 11 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 DQVANS(1)AFVER 102.52 0.0081818 0.0 21373.0 19325.0 49299.0 13318.0 25452.0 28844.0 24980.0 23791.0 39577.0 19121.0 True False 21068.21710067182 19280.254149824457 45245.82651964323 14297.450147545624 23954.963400557295 27610.409358648052 26273.34217192127 24896.416713315535 35119.421495714 22426.039372869014 0.9394533180994997 0.8597262240228507 2.017557615384443 0.6375379044791412 1.068176283929028 1.2311763526131627 1.1715551611715584 1.1101566486784635 1.5660108729765907 1.0 14.452887230394536 DQVANSAFVER ddPTM_PC-9_AZD4547_30min_R2 4 DQVANSAFVER 11 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ;;; 193.22 0.0007612999999999999 128865600.0 105080.3 88383.3 133196.0 162864.0 167163.0 130256.0 121173.0 165306.0 111865.0 126699.0 False True 138493.64959398066 116951.47329536741 131429.7340112795 125318.22102371702 143955.30289341495 122111.07172874379 131957.1622567945 139761.7560539823 117777.95552307613 122263.30657417422 1.1327490927129464 0.9565541499927924 1.0749728409442636 1.024986355556231 1.1774203309811575 0.9987548607207177 1.0792867128678483 1.1431210227345863 0.9633140050209837 1.0 16.899631964431173 -4.460451515756119 22.190968435520805 1.0542081028591803 3.0406103872644756 0.11206342975200634 0.06986586759116421 718.4927160311936 288380.87668416265 0.015984943063634127 9043.891132480652 3.463765516153802e-05 4.460451515756119 1.9864022844052953 DQVANSAFVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DQVANSAFVER 11 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ; 181.4 0.0018169 37971000.0 43505.0 48875.0 53698.0 60211.0 62356.0 44535.0 59558.0 48023.0 44376.0 45319.0 False True 50869.53723708269 53726.98699637779 54978.363970799044 56837.572876695835 50137.789426291354 42199.506200613185 53916.235077420504 46762.44713457447 45024.91504885602 53534.97595499339 0.9502112652455187 1.003586646635385 1.02696158894363 1.0616904530690165 0.9365426719989931 0.7882604866786551 1.007121682892837 0.8734933807365011 0.8410373638106845 1.0 15.708194133677349 -6.5123195332109765 24.715062132555477 0.8963976122630907 1.0097582142242378 0.36903810981633467 0.06697246772680511 452.09497331647555 1058183.3390601077 0.020921978400217423 0.022274423411745195 3.0738344014911234e-07 6.5123195332109765 0.11336060196114717 DQVANSAFVER ddPTM_PC-9_Lapatinib_30min_R1 4 DQVANSAFVER 11 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ;;; 211.63 5.1483e-06 180127000.0 235136.0 211166.0 242960.0 224486.0 258126.0 231067.0 199794.0 210953.0 220384.0 179013.0 False True 231782.91752133906 210677.0581010005 222984.7666527211 240995.44930334322 242943.53617524193 221184.80305348552 210138.35572045002 220754.64650178893 195562.03317359652 209955.15853017158 1.1039639089793105 1.003438351197859 1.0620590044739344 1.147842477367428 1.157121062783174 1.053485918621524 1.0008725538898922 1.0514371166072844 0.9314466695777485 1.0 17.679721709594595 -7.106128873004498 3.8160787482874565 1.0004654097899741 1.09198184953732 0.4731567798286329 0.04882186956850883 0.2537511854497151 6.601640362063678 0.02103099056021493 0.016164015775862253 7.831972015134664e-08 7.106128873004498 0.0915164397473458 DQVNLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 DQVNLSPK 8 0 Q5FBB7-6;Q5FBB7 Q5FBB7-6 SGOL1 Shugoshin-like 1 1 DQVNLS(1)PK;DQVNLS(1)PK 95.618 0.0063714 53864000.0 550450.0 461030.0 374390.0 406620.0 412900.0 417290.0 397370.0 432880.0 340420.0 362570.0 True False 542600.4820598316 459962.5133605988 343609.09938719263 436524.19124455686 388614.03379263345 399443.4794505007 417943.8742536573 452993.18510613445 302078.3148184798 425239.74140584277 1.275987235496838 1.0816545787558862 0.808036187425053 1.0265366774079199 0.9138704498969812 0.9393371328134581 0.9828429320174419 1.0652654044246637 0.7103717865592919 1.0 18.69791690679476 -4.926062935711063 3.5096136814795726 0.9377900279549847 1.274596513238981 0.5342792638087834 0.10031643811239975 0.18489550432815843 4.202802729958411 0.024121261685309443 0.13394160198167315 1.1855969251406212e-05 4.926062935711063 0.33680648528399626 DQYPQQSLEQIGTR ddPTM_PC-9_AZD4547_30min_R2 1 DQYPQQSLEQIGTR 14 0 H0Y6S0;Q96AE7 H0Y6S0 TTC17 Tetratricopeptide repeat protein 17 0 62.528 0.040227 56396000.0 59641.0 56366.0 80134.0 129730.0 95693.0 84466.0 50429.0 80354.0 88815.0 76172.0 False True 78605.59739013502 74585.2072027937 79071.37080137449 99822.75280852005 82407.67873141522 79184.32766736313 54917.08330608224 67937.13565122691 93509.57958058386 73505.24146495244 1.0693876494183676 1.014692363650777 1.0757242507539546 1.3580358464112505 1.121112958600476 1.0772609692754835 0.7471179226350395 0.9242488603158943 1.2721484579459488 1.0 16.1655595079458 -7.013421701565001 24.118456432582136 0.9699409667219888 1.1281843196187038 0.16887838163407287 0.14694966847603141 694.3072958438449 1247651.7523020327 0.05713249907392458 0.046355077092540074 9.695680558140097e-08 7.013421701565001 0.15824335289671498 DRAS(ph)PAAAEEVVPEWASCLK ddPTM_PC-9_AZD4547_30min_R2 1 DRASPAAAEEVVPEWASCLK 20 1 Q8N3V7-2;Q8N3V7-3;Q8N3V7 Q8N3V7-2 SYNPO Synaptopodin 1 DRAS(1)PAAAEEVVPEWASCLK 97.124 0.00021715 2750000.0 25508.0 24112.0 26483.0 33184.0 33474.0 29833.0 23891.0 32651.0 24408.0 31307.0 True False 33619.01340063994 31905.7324641408 26131.818116315204 25533.94148768926 28826.712903299052 27967.53779391052 26017.252717000367 27605.538195338253 25698.1570500804 30210.95145910918 1.1128088251753212 1.0560982333616842 0.8649783225690484 0.8451882597027671 0.9541809016613162 0.9257417076640191 0.8611861414631371 0.9137593111790147 0.8506238899778814 1.0 14.882784000348932 -5.149474772500582 4.221392683077704 0.8982966941781761 1.099863153632574 0.7054511137783186 0.04757060263354984 0.11203227670526751 3.3034022212740086 0.011940968188979 0.035772726193281694 7.088024785026817e-06 5.149474772500582 0.20156645945439788 DRAS(ph)PAAAEEVVPEWASCLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DRASPAAAEEVVPEWASCLK 20 1 Q8N3V7-2;Q8N3V7-3;Q8N3V7 Q8N3V7-2 SYNPO Synaptopodin 1 DRAS(1)PAAAEEVVPEWASCLK 62.765 0.0044449 2594300.0 11426.0 10927.0 11878.0 12203.0 12925.0 12517.0 10897.0 10669.0 12078.0 7793.0 True False 13360.196126213234 12011.760345972778 12161.216567565849 11519.305472659797 10392.439032888833 11860.586485080843 9864.757272551988 10388.950054739906 12254.617900668893 9205.80921064594 1.4512788414909799 1.304802225542751 1.321037215664014 1.2513082999089795 1.1289001102554492 1.2883806533123474 1.0715795914110424 1.1285211128127375 1.3311831279858806 1.0 13.168328827842265 -1.5228787452803376 0.22842312348885158 1.0915303239049854 2.9560752888377615 0.5480456388079702 0.08903808330326028 39.84853015257538 0.5197500553410425 0.1285664762967269 27.717264056884975 0.029999999999999995 1.5228787452803376 1.864544964932776 DRAS(ph)PAAAEEVVPEWASCLK ddPTM_PC-9_Lapatinib_30min_R1 4 DRASPAAAEEVVPEWASCLK 20 1 Q8N3V7-2;Q8N3V7-3;Q8N3V7 Q8N3V7-2 SYNPO Synaptopodin 1 DRAS(1)PAAAEEVVPEWASCLK;DRAS(1)PAAAEEVVPEWASCLK;DRAS(1)PAAAEEVVPEWASCLK;DRAS(1)PAAAEEVVPEWASCLK 112.42 1.9315e-05 18981800.0 129237.0 125190.0 142873.0 117997.0 135381.0 121744.0 134233.0 130445.0 128880.0 116562.0 True False 127394.05668083667 124900.13024665091 131126.5334457291 126674.89300645317 127418.15574928683 116537.29291912518 141182.9279328868 136505.9509128847 114364.1772334342 136709.58639089766 0.9318589869519112 0.913616473752765 0.9591612183712941 0.9265984657743606 0.9320352662391679 0.8524441920693603 1.0327214913019955 0.9985104520949196 0.836548337630321 1.0 17.060754886025208 -7.264071491165793 24.999447312262483 0.966820935551967 0.9217525122483944 0.1532449588713074 0.05469873961807424 511.6189650345354 4859243.492643684 0.022043210077785372 0.01564706891842477 5.444130271915278e-08 7.264071491165793 -0.045068423303572636 DRCKGS(ph)T(ph)CNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DRCKGSTCNR 10 2 H3BSZ9;H3BTI0;Q9H0B8-3;Q9H0B8-2;Q9H0B8 H3BSZ9 CRISPLD2 Cysteine-rich secretory protein LCCL domain-containing 2 2 DRCKGS(1)T(1)CNR 73.666 0.036507 0.0 0.0 0.0 626.9 0.0 877.93 825.84 1267.0 876.38 763.51 0.0 True False 0.0 0.0 641.8476735314896 0.0 705.9059187732373 782.5314965917682 1146.9805877143585 853.3759536013646 774.6748893309912 0.0 0.0 DRCPLPCIPTLIGT(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 2 DRCPLPCIPTLIGTPVK 17 1 Q9H0H5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 DRCPLPCIPTLIGT(1)PVK;DRCPLPCIPTLIGT(1)PVK 150.63 3.0121e-05 56257000.0 110115.0 97739.0 112431.0 99224.0 104259.0 123744.0 100531.0 131153.0 101712.0 105665.0 True False 145129.27946571534 129331.22035968231 110940.09147888956 76349.4397955182 89784.43749133837 116006.26811817994 109478.06424564742 110886.31744611809 107088.28867083666 101965.70051192307 1.423314690499724 1.2683796581631812 1.0880138215293003 0.7487757099907385 0.8805356805334719 1.1376989275390215 1.0736753996295638 1.0874864477898811 1.0502383461614584 1.0 16.63772441072036 -5.174732608065839 2.6194598513658547 1.001096269425312 1.3992312247357592 0.6264276140030371 0.10821054468214134 0.21380990242732026 2.735325777590505 0.032765356483684546 0.12412922092776747 6.687555387305094e-06 5.174732608065839 0.3981349553104472 DRCPLPCIPTLIGT(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DRCPLPCIPTLIGTPVK 17 1 Q9H0H5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 DRCPLPCIPTLIGT(1)PVK 80.303 0.0042033999999999995 25508000.0 23924.0 22737.0 22910.0 22897.0 26525.0 24196.0 30424.0 16876.0 21625.0 17078.0 True False 27973.860679461348 24994.17909640188 23456.261286658824 21614.155323075574 21327.616661305707 22927.119165376385 27542.01846931465 16433.02288160003 21941.22471451938 20174.106210626378 1.3866220583654199 1.2389237389479295 1.1626914739996572 1.0713810613176347 1.0571777722708595 1.1364626975791325 1.3652162917040334 0.8145601450707247 1.0875933974691876 1.0 14.3002171376096 -1.5228787453949268 0.5066186461404467 1.062698297935054 11.884162731693465 0.3813811680478175 0.12707981358084874 125.13282955046107 1.3053833829762798 0.07068379975721953 1445.8477789327414 0.029999999992084452 1.5228787453949268 10.821464433758411 DRCPLPCIPTLIGT(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 1 DRCPLPCIPTLIGTPVK 17 1 Q9H0H5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 DRCPLPCIPTLIGT(1)PVK 74.444 0.0069271 27146000.0 30975.0 41142.0 36928.0 30309.0 32910.0 33102.0 31635.0 27992.0 34490.0 29660.0 True False 30533.290819880676 41046.73822675695 33891.92238620225 32538.02496786005 30974.29850354944 31686.304624530847 33272.9055087562 29292.610509820053 30605.373004198806 34786.691480534224 0.877729083174419 1.1799552207983244 0.9742784077401363 0.9353584253928697 0.8904065659961337 0.9108743394657616 0.9564837612503304 0.8420637106639324 0.8798012027480342 1.0 15.086247852079985 -5.642791102968899 3.480250238822692 0.9096139205599698 1.0377143358146248 0.23498791285433374 0.07960140236932793 0.26628914781388796 6.224894454072014 0.021022711156218163 0.03899962917156048 2.2761920231234426e-06 5.642791102968899 0.128100415254655 DRDGYSYGSR ddPTM_PC-9_AZD4547_30min_R2 3 DRDGYSYGSR 10 1 Q13247-3;Q13247;A0A590UJK4;A0A590UK01;A0A590UJP7;A0A590UK80;Q13247-2 Q13247-3 SRSF6 Serine/arginine-rich splicing factor 6 0 ;; 117.71 0.0012113 26300100.0 49713.7 42637.6 67016.6 109434.0 89565.0 69514.5 53205.3 82116.6 57429.1 69447.5 False True 65521.622490802605 56419.37037628774 66127.91609613152 84205.68203844572 77130.44575443576 65167.74732594086 57940.46862767647 69427.36632174558 60464.68498216862 67016.16416317389 0.9776987881799336 0.84187704684075 0.9867457638297586 1.256498086542495 1.1509230156270236 0.9724183432413048 0.8645745299089408 1.0359794116640395 0.9022403137688776 1.0 16.0322214922163 -6.981078377682538 24.82954140892447 0.9486681880463098 1.042484533756665 0.1358770105691719 0.11162148886938679 519.5970753035397 681829.1373825509 0.04433419423555594 0.03909336035091516 1.0445316942341916e-07 6.981078377682538 0.09381634571035524 DRDGYSYGSR ddPTM_PC-9_Lapatinib_30min_R1 2 DRDGYSYGSR 10 1 Q13247-3;Q13247;A0A590UJK4;A0A590UK01;A0A590UJP7;A0A590UK80;Q13247-2 Q13247-3 SRSF6 Serine/arginine-rich splicing factor 6 0 ; 97.59700000000001 0.00659 12470600.0 38753.0 26486.4 35473.8 28092.6 27248.3 32134.4 30355.3 28743.3 33578.9 25465.8 False True 38200.3751135702 26425.072368119552 32557.28109682793 30158.623518166372 25645.60856621898 30760.086620945105 31926.948904376397 30078.818650575537 29796.89068050714 29867.52959895445 1.2789934630183626 0.8847424853324526 1.0900560419288121 1.0097461665936414 0.858645120991752 1.0298838582894347 1.068951779175404 1.007074205816757 0.9976349259749362 1.0 14.866290294040219 -4.74679559331614 24.999839103655056 0.9970175349458457 1.2789941977307486 0.6085917930457874 0.06850982905188112 549.0387293952502 937265.4947883064 0.017044692650154722 0.37252534461728787 1.791448825723272e-05 4.74679559331614 0.28197666278490296 DRDVQDETYR ddPTM_PC-9_AZD4547_30min_R2 1 DRDVQDETYR 10 1 F5GXL3;F5H1S9;G8JLB3;Q9Y606-2;Q9Y606 F5GXL3 PUS1 tRNA pseudouridine synthase;tRNA pseudouridine synthase A, mitochondrial 0 128.91 0.00034228 2651500.0 11622.0 11474.0 16834.0 18693.0 16165.0 17736.0 9250.4 16573.0 13611.0 12880.0 False True 15317.554247382686 15182.746113700718 16610.77016085979 14383.61765397104 13920.768778210822 16626.96511624031 10073.667679600689 14012.023659653327 14330.449672592766 12429.075120366886 1.232396948207562 1.221550756324703 1.3364445865839667 1.1572556698447614 1.1200164648936408 1.3377475761647428 0.8104921389600009 1.1273585141256846 1.152977959648035 1.0 13.601431325263745 -7.238190014304727 24.992048612359866 1.033320299192644 1.2296137900367905 0.48294797871551454 0.10693436839907333 742.3976970426951 798046.0927173966 0.04097944927645474 0.031721365036897015 5.778431717732991e-08 7.238190014304727 0.1962934908441465 DRDVQDETYR ddPTM_PC-9_Lapatinib_30min_R1 2 DRDVQDETYR 10 1 F5GXL3;F5H1S9;G8JLB3;Q9Y606-2;Q9Y606 F5GXL3 PUS1 tRNA pseudouridine synthase;tRNA pseudouridine synthase A, mitochondrial 0 ; 110.38 0.0022655 4804700.0 34447.0 27367.0 26019.0 26363.0 23053.0 27734.0 25241.0 23828.0 27874.0 20558.4 False True 33955.77946319387 27303.633392923453 23879.818256244496 28301.82296438993 21697.06786394182 26547.88147111166 26547.855474838474 24935.135868390687 24734.536593767418 24111.89204765392 1.4082586051764343 1.1323720817495984 0.9903751314517019 1.1737703083795819 0.8998492453873165 1.101028547185071 1.1010274690335458 1.0341426470850872 1.0258231309630503 1.0 14.55745724246283 -4.784430010100183 2.9454270146926316 1.046019468802213 1.4685272020439681 0.7096405161600632 0.07059852710194038 0.20203303613304363 2.513817483996431 0.017141561884850935 0.20503402537672302 1.6427443792490794e-05 4.784430010100183 0.42250773324175506 DRDVTFSPATIENELIK ddPTM_PC-9_Lapatinib_30min_R1 1 DRDVTFSPATIENELIK 17 1 H7C2D6;P55145 H7C2D6 MANF Mesencephalic astrocyte-derived neurotrophic factor 0 114.63 0.0015755 0.0 8646.5 9960.5 10103.0 9637.7 9628.8 10983.0 9551.5 10121.0 10424.0 8288.1 False True 8523.199324426098 9937.43707422129 9272.370338707797 10346.488608424715 9062.45291494916 10513.28269262348 10046.029934151567 10591.258608527029 9249.939350413697 9720.687041800938 0.8768103826174632 1.0222978099683986 0.9538801423021553 1.0643783267512577 0.932285225928863 1.0815369991250843 1.0334691252739223 1.089558645698854 0.9515725905624849 1.0 13.246842569354294 -3.9131146549820532 1.318960543919675 1.0208752365453468 5.2834704062540236e-18 0.3592037386113487 0.053496268684838866 12.035151383914286 3.262893021719852 0.0146760325810944 28.48209076801901 0.00012214771441438366 3.9131146549820532 -1.0208752365453468 DRDWSHSGNPGASR ddPTM_PC-9_AZD4547_30min_R2 2 DRDWSHSGNPGASR 14 1 Q96MG7 Q96MG7 NDNL2 Melanoma-associated antigen G1 0 ; 87.18 0.0027983 3095100.0 6056.8 5356.799999999999 11380.900000000001 17830.699999999997 14763.7 11123.9 8439.0 13434.8 10789.9 12916.5 False True 7982.736410733732 7088.280842066584 11229.981829852042 13720.107596568843 12714.015095012144 10428.320774500764 9190.054651490771 11358.760360991404 11360.232085982576 12464.297266476618 0.6404481728948908 0.5686867611165602 0.9009719192156679 1.1007525978596318 1.0200346496233812 0.8366553325511804 0.7373102915483174 0.9113037115651427 0.9114217868131657 1.0 13.60551392593695 -5.282821369997197 7.990789200543417 0.923948242880732 0.6043186539828659 0.6439461642169922 0.09597749566805754 0.13361451790388595 43.602470898545924 0.02820030673032691 0.06137443360854148 5.2140912820208846e-06 5.282821369997197 -0.3196295888978661 DRDWSHSGNPGASR ddPTM_PC-9_Lapatinib_30min_R1 1 DRDWSHSGNPGASR 14 1 Q96MG7 Q96MG7 NDNL2 Melanoma-associated antigen G1 0 79.639 0.005649100000000001 916340.0 4963.4 4956.4 5293.5 4012.4 4641.3 3344.0 4181.2 4524.8 5774.8 3624.2 False True 4892.621005823913 4944.9237603203055 4858.2888635009085 4307.4852809740205 4368.307859146884 3200.984915244735 4397.682077231274 4735.0387265945155 5124.381212660111 4250.638141057053 1.1510321141115087 1.1633367970228106 1.1429551757357412 1.0133737895418289 1.0276828358907466 0.7530598486675016 1.034593378992655 1.1139594972478652 1.2055557407165631 1.0 12.053463731518935 -5.7406089750187785 5.4547103072984635 1.0152233711382175 1.1554785872727766 0.23746493806502744 0.1075239974534674 0.27264035883406573 23.228546977175643 0.03269735037582712 0.05497931794056203 1.8171510316175347e-06 5.7406089750187785 0.14025521613455916 DRDYFDYSR ddPTM_PC-9_AZD4547_30min_R2 1 DRDYFDYSR 9 1 Q9HCG8;B7WP74 Q9HCG8 CWC22 Pre-mRNA-splicing factor CWC22 homolog 0 106.18 0.0028336 0.0 16371.0 18179.0 29405.0 34228.0 30364.0 26705.0 23923.0 30099.0 21486.0 27858.0 False True 21576.63746204629 24055.006240279356 29015.0704871143 26337.263417328482 26148.48272079144 25035.13212839407 26052.10065500815 25447.89115621225 22621.70609546164 26882.69989931526 0.8026216690606987 0.8948136284812699 1.079321295695205 0.9797105021434 0.9726881161016673 0.9312729830768133 0.9691028338887842 0.9466270594666142 0.8414968057593741 1.0 14.714390418549582 -4.962785225213373 4.930346701850472 0.9644170158024701 0.8158941968199199 0.4459418957493627 0.056300303529819046 0.17698128535756072 10.344269682312158 0.014524695906966721 0.06091046423362705 1.0894687429769566e-05 4.962785225213373 -0.14852281898255015 DRDYFDYSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DRDYFDYSR 9 1 Q9HCG8;B7WP74 Q9HCG8 CWC22 Pre-mRNA-splicing factor CWC22 homolog 0 86.882 0.014674000000000001 5997200.0 18409.0 22170.0 25696.0 31072.0 30935.0 30908.0 29925.0 28652.0 22860.0 20123.0 False True 21525.280105676466 24370.891083574308 26308.690092622663 29331.136576783163 24873.50881875559 29287.130069575673 27090.28736176178 27899.91535930341 23194.284253128924 23771.14060641964 0.9055215507775568 1.0252301934974335 1.106749168170657 1.2338968946598208 1.0463742245518601 1.2320456369546853 1.139629259289551 1.1736885419696164 0.9757329123224768 1.0 14.536923509070672 -4.939345505733902 2.149982511971801 1.1270806441408285 0.8841104467056898 0.366349693562363 0.08407153749041865 0.45329839211344397 3.1133634991607355 0.021623980631421527 0.1898419664591106 1.1498852264645656e-05 4.939345505733902 -0.2429701974351387 DRDYFDYSR ddPTM_PC-9_Lapatinib_30min_R1 1 DRDYFDYSR 9 1 Q9HCG8;B7WP74 Q9HCG8 CWC22 Pre-mRNA-splicing factor CWC22 homolog 0 117.53 0.0024017 4965100.0 99263.0 94656.0 85846.0 85885.0 83729.0 81619.0 74935.0 80781.0 86115.0 66018.0 False True 97847.49141739505 94436.82984764708 78788.07325514308 92201.26940396117 78804.22483754755 78128.34563318187 78814.767640229 84534.38016553911 76415.82186884836 77429.12333654435 1.2637039811506405 1.2196551604643517 1.0175508886067595 1.1907828144096368 1.01775948689263 1.0090304818975977 1.0178956475803294 1.0917646555045173 0.9869131739579217 1.0 16.240588687398215 -1.522882079936714 0.423409448528086 1.015764648826693 6.1174789764972415 0.6700879782867739 0.056678161952933244 46.14626061295385 0.587503410584292 0.037146824146864404 199.89409202343708 0.029999769650982472 1.522882079936714 5.101714327670549 DRDYSDHPS(ph)GGSYR ddPTM_PC-9_AZD4547_30min_R2 1 DRDYSDHPSGGSYR 14 1 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 DRDYS(0.001)DHPS(0.977)GGS(0.022)Y(0.001)R 92.633 0.0055187 0.0 3320.8 5573.8 14011.0 23383.0 13215.0 17229.0 11364.0 17632.0 10209.0 15915.0 True False 4376.745323069042 7375.421848400303 13825.204985375225 17992.410613748736 11380.325357504244 16151.667906388386 12375.373985014943 14907.379543052404 10748.62689791343 15357.82069414899 0.284984791151813 0.4802388304487879 0.9002061725230547 1.1715471206538743 0.7410117349423093 1.051690095101959 0.8058027392994439 0.9706702428640677 0.6998796972547304 1.0 13.906685888785049 -5.159979723230035 3.1575772658425434 0.9220785860732312 0.31737100942755175 0.7184355217152956 0.13636850521028493 0.12708887653254564 2.3579782317644438 0.034476770623462265 0.11778825750940383 6.918632725610724e-06 5.159979723230035 -0.6047075766456795 down DRDYSDHPSGGSYR ddPTM_PC-9_AZD4547_30min_R2 3 DRDYSDHPSGGSYR 14 1 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 0 ;; 78.529 0.0062375 60467300.0 3038.0 4972.7 80114.0 262638.0 113084.0 81393.0 24030.2 130123.0 43507.7 80685.0 False True 4004.020805674462 6580.028028551466 79051.63601444237 202090.86681665064 97384.23857192679 76303.48284315219 26168.841247334236 110015.48027907262 45807.428199270056 77860.24270860254 0.05142574266894842 0.08451075670516063 1.0153016901103005 2.5955591684062687 1.2507569355568822 0.980005715223922 0.33610017560917416 1.4129866084647762 0.5883288647160733 1.0 16.248599221459813 -5.287801378293324 5.0714806525416956 1.188468968562102 0.056096000042934906 0.36790339430141505 0.5667229062534674 0.18992926369592816 14.096935061901748 0.15900887711039574 0.36726642135172755 5.154643348836171e-06 5.287801378293324 -1.132372968519167 DRDYSDHPSGGSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DRDYSDHPSGGSYR 14 1 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 0 66.708 0.016222 11001000.0 3129.5 5104.6 42222.0 23339.0 36526.0 47189.0 23363.0 19898.0 31679.0 13125.0 False True 3659.2625395575296 5611.350952873864 43228.7326078267 22031.391496058925 29368.9925040849 44714.32576851322 21149.887506527677 19375.6985836737 32142.245444220083 15504.458602557173 0.2360135644435854 0.36191853561067755 2.788148474961707 1.4209713515843279 1.8942288316498217 2.8839656330301287 1.3641164808579254 1.2496855956310553 2.073096924449772 1.0 13.920395529167008 -5.183340683460771 8.896435414513979 1.8506216943419562 0.2862371513805066 0.5178074198977878 0.5925398743945907 0.30262440379795236 32.2774117797865 0.1484126157342617 0.39510633692360203 6.5563075323654405e-06 5.183340683460771 -1.5643845429614496 DRDYSDHPSGGSYR ddPTM_PC-9_Lapatinib_30min_R1 2 DRDYSDHPSGGSYR 14 1 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 0 ; 89.44 0.0023984 16141200.0 19018.5 7116.8 76596.0 15402.8 41810.0 59111.0 21477.5 27112.6 88786.0 18770.3 False True 18747.29270243425 7100.3214868548885 70298.57254911054 16535.57329423453 39350.8180016227 56582.96032447111 22589.499859785414 28372.350375412512 78785.98572197142 22014.721345147394 0.8515798319003766 0.32252606678666773 3.1932528895990835 0.7511143582055556 1.7874774513235718 2.5702328654250004 1.0261088253458504 1.2887898933895205 3.578786416905425 1.0 14.426180962796854 -5.218638116594433 24.9986228972446 1.8575368629824454 0.5870521370162116 0.24666197746714114 0.9150911702760859 665.5530241420352 388722.6419647538 0.22202802253734996 0.5874221070480853 6.044520897707133e-06 5.218638116594433 -1.2704847259662337 DREDS(ph)PER ddPTM_PC-9_AZD4547_30min_R2 1 DREDSPER 8 1 Q14677-2;Q14677;Q14677-3 Q14677-2 CLINT1 Clathrin interactor 1 1 DREDS(1)PER 68.786 0.020122 824120.0 773.22 903.12 0.0 975.01 614.98 0.0 622.77 0.0 1298.0 864.3 True False 1019.0878760248868 1195.0358785258313 0.0 750.2365082543364 529.6006423275038 0.0 678.1953235346498 0.0 1366.6096300804807 834.0411200724456 1.2218676651534495 1.4328260918622686 0.0 0.8995198080751344 0.6349814530505429 0.0 0.8131437494061937 0.0 1.6385398719451336 1.0 9.70397470325543 -5.2349330350195835 24.851492083893547 0.5823642376576514 1.327347123084118 0.23875163661777765 0.49862193534690025 884.6366000045847 829403.5174433561 0.11794920416144193 0.31186239805273774 5.82192980679707e-06 5.2349330350195835 0.7449828854264666 DREDS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 1 DREDSPER 8 1 Q14677-2;Q14677;Q14677-3 Q14677-2 CLINT1 Clathrin interactor 1 1 DREDS(1)PER 56.358999999999995 0.040494999999999996 1227900.0 756.49 2987.4 1053.3 810.67 3143.1 1055.4 3432.2 4420.5 2072.4 3210.5 True False 745.7023138767241 2980.482858845307 966.70173985558 870.2893761158437 2958.2290375723574 1010.2630022575636 3609.9025221164234 4625.89256782865 1838.984488660529 3765.4306472776525 0.19803905150021958 0.791538375829641 0.25673072495824356 0.23112612012786618 0.7856283423281506 0.26829945812120265 0.9586957934615863 1.2285162046931066 0.4883862327912177 1.0 11.878599158101729 -7.27235633565157 24.684250936793582 0.9379426263031925 0.4390504453074481 0.4575960040087015 0.2643662591280741 559.9054357706447 1265992.5925147887 0.1055215474017855 0.07193868121051764 5.341259328843968e-08 7.27235633565157 -0.4988921809957444 DREDYVPYTGEK ddPTM_PC-9_AZD4547_30min_R2 1 DREDYVPYTGEK 12 1 Q9NYL9 Q9NYL9 TMOD3 Tropomodulin-3 0 94.68799999999999 0.0062619 3407100.0 47289.0 50749.0 58050.0 59910.0 67384.0 62560.0 60069.0 61644.0 57028.0 60213.0 False True 62325.91832769569 67152.62179921551 57280.21907080381 46098.67510027313 58028.89473250593 58648.11331032893 65415.02463092772 52118.33623819886 60042.38365503056 58104.96119741081 1.0726436614585153 1.1557123594156684 0.9858059947100739 0.7933690024101989 0.9986908783116394 1.0093477751593838 1.1258079049167775 0.8969687813942002 1.0333434945604278 1.0 15.82637373060313 -5.282378687160044 15.981316626653626 0.9769335146071547 1.1141758840423808 0.28658863060877626 0.08427396696175543 9.327580914493007 7120.312167864747 0.02287795042689191 0.04805943905804785 5.219408792612228e-06 5.282378687160044 0.13724236943522605 DREDYVPYTGEK ddPTM_PC-9_Lapatinib_30min_R1 2 DREDYVPYTGEK 12 1 Q9NYL9 Q9NYL9 TMOD3 Tropomodulin-3 0 ; 111.31 0.0018454 3971800.0 56210.0 68184.0 72187.0 53423.0 63034.0 71537.0 64552.0 60303.0 63414.0 63047.0 False True 55408.43509234847 68026.12413721262 66252.06350987828 57351.9056339037 59326.46404961214 68477.52927089194 67894.18670463825 63104.897526924775 56271.64754097602 73944.5899451531 0.7493237183876001 0.9199608002109366 0.8959690432933552 0.7756065139646229 0.8023097307540192 0.9260654406452692 0.9181765258959093 0.8534079041310737 0.7609974926186537 1.0 16.1741569779243 -6.754604526727452 24.98823495668452 0.8842204081269909 0.8345025479864896 0.14662088463463663 0.07435323824539161 423.78455009012924 1549356.6311007612 0.025320637478985223 0.024788569197949816 1.759525127363295e-07 6.754604526727452 -0.04971786014050128 DREEALHQFR ddPTM_PC-9_AZD4547_30min_R2 4 DREEALHQFR 10 1 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDT5;A0A2R8YDH3;A0A2R8Y7T2;O15523-2;O15523;A0A0J9YVQ7;A0A087WVZ1 A0A2R8Y5G6 DDX3X;DDX3Y ATP-dependent RNA helicase DDX3X;ATP-dependent RNA helicase DDX3Y 0 ;;; 75.509 0.010998 58833800.0 47190.9 43702.1 65642.6 82942.0 64169.4 59127.0 51819.4 64665.4 44905.0 58913.0 False True 62196.62456830249 57827.949183855635 64772.13623388708 63821.00334112594 55260.586454470875 55429.7793430278 56431.226212520545 54672.84829306379 47278.586624625554 56850.4738017216 1.0940388075783987 1.0171937948229455 1.1393420652885673 1.12261163493053 0.9720338769243014 0.9750099803275382 0.9926254336830459 0.9616955609507715 0.8316304766345468 1.0 15.794884752388093 -6.336655481083761 5.3612452065088405 0.9549586341041307 1.0909393094029372 0.6195039745231187 0.05296880551319408 0.15880135318602118 8.243608532283046 0.017142563615732135 0.019588304646294026 4.606218326706289e-07 6.336655481083761 0.13598067529880642 DREEALHQFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DREEALHQFR 10 1 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDT5;A0A2R8YDH3;A0A2R8Y7T2;O15523-2;O15523;A0A0J9YVQ7;A0A087WVZ1 A0A2R8Y5G6 DDX3X;DDX3Y ATP-dependent RNA helicase DDX3X;ATP-dependent RNA helicase DDX3Y 0 ;;; 108.43 0.00091403 52121900.0 48032.1 48792.7 55449.6 64705.0 60713.7 55597.3 63663.0 58984.0 56429.6 40067.2 False True 56162.98585278192 53636.516796279524 56771.728757779034 61079.788626440386 48817.28632194216 52681.67971454702 57632.37975979418 57435.73249871391 57254.77614568518 47331.06618821931 1.1865987896710612 1.13322012614264 1.1994601712967434 1.2904798802449782 1.0314005209139525 1.1130465454771326 1.2176438098945437 1.2134890912939047 1.2096658866293588 1.0 15.530499800403073 -6.247123077230074 24.992172835689495 1.1449958417159216 1.1972826407567925 0.1505393789301358 0.07874537531909599 2168.901598829498 3786278.826000894 0.024212360044848072 0.031121262712846397 5.660788419407215e-07 6.247123077230074 0.05228679904087086 DREEALHQFR ddPTM_PC-9_Lapatinib_30min_R1 3 DREEALHQFR 10 1 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDT5;A0A2R8YDH3;A0A2R8Y7T2;O15523-2;O15523;A0A0J9YVQ7;A0A087WVZ1 A0A2R8Y5G6 DDX3X;DDX3Y ATP-dependent RNA helicase DDX3X;ATP-dependent RNA helicase DDX3Y 0 ;; 123.86 0.00019458 61310300.0 61882.9 55892.3 60011.5 58893.0 64325.5 60568.3 45759.9 53441.1 64942.7 52862.0 False True 61000.43849806604 55762.884813362674 55077.58612108907 63224.187681288786 60542.00055879886 57977.93500060338 48129.1237170897 55924.16860232724 57628.16924905137 61999.12626581256 0.9838919057751752 0.899414042938075 0.8883606824546469 1.0197593335464752 0.9764976412608385 0.9351411623452742 0.7762871288015065 0.902015431033015 0.929499699753488 1.0 15.919960263744747 -7.0186886228202034 24.928778373458755 0.8883464670864527 0.95114719484659 0.11465260929067422 0.0632022054937745 1335.7535665828616 1781759.61363861 0.024097242753959938 0.01900646883653018 9.578805991570307e-08 7.0186886228202034 0.06280072776013734 DREEDEEDAYER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DREEDEEDAYER 12 1 P49756 P49756 RBM25 RNA-binding protein 25 0 ; 150.14 0.00022149 11131800.0 26939.0 27054.0 23890.0 31272.0 33962.0 24811.0 34360.0 30971.0 26168.0 23297.0 False True 31499.240630496963 29739.742326342777 24459.628203329536 29519.931225191922 27307.389898256908 23509.86748273074 31105.172055142364 30158.04406648701 26550.657495007763 27520.56168104948 1.1445711390471796 1.0806371857890318 0.8887764896227505 1.072650026816829 0.992254090404726 0.8542655398970115 1.130252078995947 1.0958367934493753 0.9647571078932743 1.0 14.748222294582023 -5.009583040112713 21.414252728718065 1.0037016096088958 1.1285882048897249 0.24808683900562212 0.08167839117161876 94.30808044731303 210771.418125056 0.020904167182770033 0.06613498463255572 9.781759028952155e-06 5.009583040112713 0.12488659528082913 DREEDEEDAYER ddPTM_PC-9_Lapatinib_30min_R1 2 DREEDEEDAYER 12 1 P49756 P49756 RBM25 RNA-binding protein 25 0 ; 135.1 7.6961e-05 10057300.0 22130.7 23301.0 22244.0 16363.4 22634.0 16713.1 16062.4 17320.1 22973.0 19241.3 False True 21815.112159726665 23247.047966109174 20415.184184323094 17566.819022702202 21302.712620156126 15998.31967313898 16894.032478073193 18124.855076133685 20385.538823585375 22567.133067579354 0.966676276264216 1.0301285456373104 0.9046423452721242 0.7784249319617493 0.9439707098089596 0.708921227398737 0.7486122595848778 0.8031527541339496 0.9033286932167682 1.0 14.461935529496978 -5.495514947338057 4.219699369997905 0.8278448804268929 0.9955356871307506 0.336897017142365 0.08634542948531719 0.2086056417807721 8.476225811492933 0.02300737615818605 0.04731854507730925 3.1951043953534263e-06 5.495514947338057 0.16769080670385772 DREEDEEDAYERR ddPTM_PC-9_AZD4547_30min_R2 2 DREEDEEDAYERR 13 2 P49756 P49756 RBM25 RNA-binding protein 25 0 ; 122.69 0.00072091 23648000.0 37953.0 29266.0 45820.0 64633.0 56958.0 45666.0 37339.0 42080.0 37668.0 47659.0 False True 50021.2645285592 38725.66217217756 45212.39686174382 49732.86041989574 49050.36486664596 42810.497800982725 40662.09866477236 35577.50290220307 39659.05357925389 45990.472916270584 1.0876440566207484 0.8420366157721577 0.9830817992251718 1.08137310330421 1.0665331699447005 0.9308557856955012 0.8841417816859817 0.7735841935562355 0.8623319366916804 1.0 15.489047412458651 -7.0727069142649075 3.221658571956618 0.8614879613815444 1.0047263038005652 0.34108488271736037 0.08456631092597837 0.28551632794408294 5.766076615544549 0.03506827473544018 0.02718817274629593 8.458494782095604e-08 7.0727069142649075 0.14323834241902078 DREEDEEDAYERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DREEDEEDAYERR 13 2 P49756 P49756 RBM25 RNA-binding protein 25 0 108.35 0.0036751999999999996 15299000.0 18428.0 10876.0 13737.0 19386.0 22183.0 24423.0 17105.0 20707.0 21609.0 19896.0 False True 21547.49643040938 11955.697403020042 14064.542177862619 18299.865270259994 17836.400391997922 23142.214885765698 15484.690570524148 20163.46319088007 21924.990744788396 23502.987303350656 0.9167981989820292 0.5086884168684209 0.5984150864029755 0.7786186936181985 0.758899290621457 0.984649933520003 0.6588392518221122 0.8579106532557887 0.9328597450955821 1.0 14.520556519055704 -7.517635328634207 0.363214247619214 1.0064339337055586 0.6484787157535183 0.328260799526908 0.13121555770220936 1.5177519031345856 0.5465173106464418 0.1683787886352539 0.18617271228275314 3.0364397725864776e-08 7.517635328634207 -0.3579552179520402 DREEDEEDAYERR ddPTM_PC-9_Lapatinib_30min_R1 1 DREEDEEDAYERR 13 2 P49756 P49756 RBM25 RNA-binding protein 25 0 89.46 0.013574000000000001 0.0 14184.0 17021.0 22280.0 16993.0 22056.0 22562.0 20003.0 15672.0 17899.0 16114.0 False True 13981.733558972976 16981.588920267124 20448.2244032871 18242.72190698623 20758.709443764412 21597.07585459081 21038.657464569314 16400.178333448843 15883.026135174096 18899.283429444655 0.7398023110860252 0.8985308349738909 1.0819576562055908 0.9652599779822595 1.0983860589879728 1.142745751986716 1.1131986851835642 0.8677672036971379 0.8404036160666654 1.0 14.206043914927827 -4.917052381412479 2.951119538642507 1.0182007964583624 0.7288781751720363 0.4360566361579159 0.09658009053559019 0.31211702765678273 4.699725543210928 0.02758893267340986 0.18559832743135804 1.2104521288951609e-05 4.917052381412479 -0.289322621286326 DRELALR ddPTM_PC-9_AZD4547_30min_R2 2 DRELALR 7 1 Q5JVM0;A0A0A0MRM8;A0A1Y0BRN3;A0A590UJ40;E7EW20;Q9UM54-5;Q9UM54-2;Q9UM54-6;Q9UM54-4;Q9UM54-1;Q9UM54 Q5JVM0 MYO6 Unconventional myosin-VI 0 ; 94.006 0.017612 2797100.0 17695.0 18572.6 23293.0 27556.0 22447.0 24244.0 21950.4 24977.0 16598.1 23103.0 False True 23321.641921135477 24575.829743011836 22984.119600624163 21203.38993595603 19330.621513423976 22728.018847436288 23903.943076440686 21117.378564361392 17475.44168030725 22294.171002005925 1.0460869757856035 1.102343286987465 1.0309474884065506 0.9510732618875243 0.8670706576927528 1.0194601470218976 1.0722059624594213 0.9472152412602087 0.7838569856997549 1.0 14.444378934279497 -5.629145876369548 3.5768810203873165 0.9511397191621044 1.0732181862247856 0.3158316804438611 0.07647654888408689 0.2969188729289069 7.296486899736755 0.022617937488884965 0.0420738961660846 2.3488437287419417e-06 5.629145876369548 0.12207846706268122 DRELALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DRELALR 7 1 Q5JVM0;A0A0A0MRM8;A0A1Y0BRN3;A0A590UJ40;E7EW20;Q9UM54-5;Q9UM54-2;Q9UM54-6;Q9UM54-4;Q9UM54-1;Q9UM54 Q5JVM0 MYO6 Unconventional myosin-VI 0 107.59 0.0041927 0.0 6729.1 7719.3 5605.0 7392.2 7900.2 8228.7 7246.5 7238.6 8050.8 5387.6 False True 7868.203724216832 8485.621088923554 5738.644457080873 6978.038999835758 6352.212522060225 7797.172486201546 6560.059059883265 7048.594419930667 8168.527719382772 6364.329231781868 1.2362974066339922 1.3333095727588204 0.9016888108841884 1.0964296072222626 0.9980961529046714 1.225136570129719 1.0307541959212247 1.1075156804792168 1.2834860394385614 1.0 12.635792754016343 -5.232819397472504 24.98610867592587 1.0852590260502277 1.2848035369308635 0.36552348923477707 0.10757360220995446 765.1737293748395 668017.4817494577 0.026682843864821074 0.07056658297156448 5.850333212445318e-06 5.232819397472504 0.19954451088063574 DRELDLR ddPTM_PC-9_AZD4547_30min_R2 2 DRELDLR 7 1 P09661;H0YKK0 P09661 SNRPA1 U2 small nuclear ribonucleoprotein A 0 ; 104.75 0.013356999999999999 14170200.0 38665.0 40856.0 53018.0 70102.0 58443.0 54000.0 46770.0 48307.0 41830.0 50838.0 False True 50959.66571803915 54061.9030173746 52314.94667865419 53941.066965103426 50329.198249611865 50623.3714635192 50932.43939450449 40842.263134427856 44041.04840236249 49058.17709388292 1.038759871173308 1.1019957572805044 1.06638586628563 1.0995326398263043 1.0259084464817472 1.0319048619894897 1.0382048908387846 0.8325271250146082 0.8977310412101305 1.0 15.582206006708816 -7.659578183200004 6.318845821417678 0.8997571798306155 1.060600137973748 0.6898817113920421 0.04527787933456766 0.1069189119482762 5.683598377635391 0.021358260806181747 0.01213618847013704 2.1898875614213107e-08 7.659578183200004 0.16084295814313243 DRELWVQR ddPTM_PC-9_AZD4547_30min_R2 1 DRELWVQR 8 1 Q9Y3C8 Q9Y3C8 UFC1 Ubiquitin-fold modifier-conjugating enzyme 1 0 101.25 0.0060182 3086100.0 16331.0 14004.0 16968.0 28379.0 21719.0 22248.0 15287.0 25397.0 18623.0 23956.0 False True 21523.91829409797 18530.519136854182 16742.993233305755 21836.660001179276 18703.69174722925 20856.829042969915 16647.51338515693 21472.47721500124 19607.37376039197 23117.3077316389 0.9310737454361877 0.8015863850569792 0.7242622466106161 0.9446022112381669 0.8090774221788349 0.9022170438309631 0.7201320144375093 0.9288485261462127 0.8481685665133423 1.0 14.496685769240152 -9.06523960123269 0.9465502422662552 1.0002629857405188 0.8371725680230044 0.2617692393471236 0.0780195187742572 2.628482778996156 3.3830905706802596 0.0748339272147317 0.023575534405035684 8.605188710229261e-10 9.06523960123269 -0.1630904177175143 DRELWVQR ddPTM_PC-9_Lapatinib_30min_R1 1 DRELWVQR 8 1 Q9Y3C8 Q9Y3C8 UFC1 Ubiquitin-fold modifier-conjugating enzyme 1 0 114.5 0.0040343 0.0 12182.0 12471.0 14789.0 12465.0 13202.0 14160.0 11680.0 11050.0 14588.0 11042.0 False True 12008.282446094807 12442.124165715952 13573.105507190883 13381.71768202103 12425.48431613066 13554.409808572202 12284.733249321078 11563.423340008276 12944.945821549796 12950.59498745984 0.9272378958435902 0.9607376477886735 1.048068101916076 1.0332897982663074 0.9594527763521562 1.0466244849520072 0.9485844674485211 0.8928874195513973 0.9995637910138095 1.0 13.660730760529932 DRENYDR ddPTM_PC-9_AZD4547_30min_R2 2 DRENYDR 7 1 P17844-2;P17844;J3KTA4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 ; 107.32 0.012865999999999999 56341000.0 55892.0 36930.0 36030.0 39680.0 46097.0 42650.0 34085.0 31267.0 56655.0 73378.0 False True 73664.49337417928 48866.90029448904 35552.21865841621 30532.389049888814 39697.227242139474 39983.08875776099 37118.49896860564 26435.403594182135 59649.6676365251 70809.05855452486 1.0403258407602702 0.6901221579843521 0.5020857413467806 0.43119326359039306 0.5606235706632302 0.5646606461653907 0.5242055144685113 0.3733336402690084 0.8424016482381737 1.0 16.111646314656 -8.485159938304982 6.0853333065076525 0.9996148097254826 0.5784657895274453 0.3907181359088234 0.1729252279775714 0.17143777664737717 17.845664182423878 0.1730537822655779 0.04484928711273018 3.2722016680640766e-09 8.485159938304982 -0.42114902019803724 DRENYDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DRENYDR 7 1 P17844-2;P17844;J3KTA4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 ; 96.19 0.016702 43270000.0 23654.0 41642.0 46308.0 34512.0 70834.0 68807.0 29001.0 55881.0 76597.0 71711.0 False True 27658.155012204435 45775.942557609465 47412.15834406799 32578.404529413638 56954.58618612358 65198.63979219923 26253.81533094248 54414.18296081363 77717.08621771265 84711.63663603649 0.3264977057524893 0.5403737240290349 0.5596888482721011 0.38458003909647903 0.6723348579703274 0.7696538796945355 0.3099198218037268 0.64234602377716 0.917431055565885 1.0 16.37027254230619 -8.22534367371537 3.0913946673067656 0.9855334645954874 0.5214308936658942 0.6214996168813653 0.13833617959843011 0.1704980257395169 3.0652763458975247 0.12258778235672524 0.03654697591512786 5.9519095991257465e-09 8.22534367371537 -0.4641025709295932 DRENYDR ddPTM_PC-9_Lapatinib_30min_R1 1 DRENYDR 7 1 P17844-2;P17844;J3KTA4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 113.41 0.011701000000000001 27538000.0 14294.0 20288.0 14604.0 14153.0 21296.0 16537.0 23594.0 26289.0 25434.0 20661.0 False True 14090.164938801436 20241.02438249101 13403.315493070246 15193.85883302397 20043.411149546904 15829.751059629838 24815.58187367137 27510.482912712898 22569.35508810649 24232.22632094801 0.5814639048093126 0.8352936339569126 0.5531194416702643 0.6270104377446057 0.8271386575908626 0.6532520309925262 1.0240735434291923 1.135284993972301 0.9313776946939448 1.0 14.56463933715096 -7.265857366356215 23.69550001832823 1.0339578609018003 0.6851998307356382 0.7433405302577902 0.09865522754773452 90.87797165025502 487411.4677971073 0.03932715884480447 0.02759023398919746 5.421789268756179e-08 7.265857366356215 -0.34875803016616214 DRET(ph)S(ph)S(ph)IEPLPS(ph)DS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DRETSSIEPLPSDSPK 16 1 Q9HAQ2 Q9HAQ2 KIF9 Kinesin-like protein KIF9 5 DRET(1)S(1)S(1)IEPLPS(1)DS(1)PK 42.309 0.04565 8173300.0 14988.0 13651.0 12642.0 16237.0 13963.0 13451.0 18118.0 13282.0 16380.0 11766.0 True False 17525.172373506382 15006.181063683938 12943.433225051976 15327.293531064257 11227.05038423418 12745.605880867806 16401.731877039263 12933.361573442266 16619.52651208449 13899.082660395254 1.2608869809403676 1.079652623870157 0.931243704444873 1.102755764935381 0.8077547747971241 0.9170105820858075 1.1800585893179256 0.9305190773701374 1.1957283022311254 1.0 13.762702047752104 -4.826215188411561 3.1861703978316394 1.0045284183468586 1.2855483945293413 0.3007783557132746 0.11606084352172834 0.3740202834474061 6.060232666713814 0.02906537452275757 0.24939779063624595 1.4920549286490434e-05 4.826215188411561 0.28101997618248276 DRFS(ph)AEDEALSNIAR ddPTM_PC-9_Lapatinib_30min_R1 1 DRFSAEDEALSNIAR 15 1 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608;C9JJC9;C9JC17;C9J321;C9J0U5 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 DRFS(1)AEDEALSNIAR 72.883 0.0088383 1046800.0 3642.7 3713.0 5790.3 3746.7 5420.2 4428.7 4129.2 4222.7 4843.6 3331.3 True False 3590.754430010635 3704.4027766260388 5314.243885204367 4022.2448166248055 5101.3944925232045 4239.294824803931 4342.9897716692285 4418.902057724247 4298.062762630831 3907.11076632177 0.9190306200074899 0.948118187115907 1.3601467178795392 1.0294678234606143 1.3056692777936665 1.085020384204486 1.1115604423362186 1.130989706207968 1.1000616618497128 1.0 11.931886441068727 -5.038833725916958 24.583287558128966 1.1446573969835052 0.9263023388245154 0.3769942544904168 0.10650601790101033 345.1041062943923 218464.8361128139 0.025022973816283135 0.06623563390068517 9.144632860763244e-06 5.038833725916958 -0.2183550581589898 DRGFGAPR ddPTM_PC-9_Lapatinib_30min_R1 1 DRGFGAPR 8 1 P17844-2;P17844;J3QRQ7;J3QR02;J3KRX8;X6RLV5;J3QKN9 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 79.71300000000001 0.026345 3219200.0 10479.0 6558.2 8054.1 8704.8 7322.4 8308.0 7482.3 6283.4 9159.2 4827.6 False True 10329.567538386747 6543.014890834606 7391.922987725081 9344.98003036155 6891.710828392297 7952.68620689391 7869.696882824924 6575.349702679454 8127.594445348151 5662.044227627349 1.8243530292442276 1.155592331636806 1.3055219441163972 1.6504604440854955 1.2171771450962745 1.4045609478092056 1.389903816792099 1.161303133344619 1.4354523063755682 1.0 12.467107303197418 -13.758308854031746 0.10365519823572314 1.7900938181423323e-11 1.6301152127714926 0.3180947999055781 0.1923335888006614 191.55499270312365 1.576986684921264 43.704581594197464 2.9603452290132677 1.7445810307152126e-14 13.758308854031746 1.6301152127535916 DRGS(ph)LY(ph)AQPQLPSPAQRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DRGSLYAQPQLPSPAQRK 18 2 A0A590UJ23 A0A590UJ23 2 DRGS(1)LY(1)AQPQLPSPAQRK 64.76100000000001 0.014324000000000002 19758000.0 8971.0 4257.9 97951.0 13121.0 51391.0 61674.0 13499.0 23356.0 52338.0 21445.0 True False 10489.613114673455 4680.596172519222 100286.52332123631 12385.87290885595 41321.30246338028 58439.70686912806 12220.276995703342 22742.929747727558 53103.34423623189 25332.808741473393 0.41407225001073306 0.18476420124928444 3.9587605284783556 0.48892616035025455 1.6311378215133112 2.3068783041595378 0.4823893442063145 0.8977658174355599 2.096228048700111 1.0 14.628719422361716 -8.241501638883335 24.68262342142146 1.5481147106830424 1.3382313902163174 0.0070483181431091335 1.110155563698968 6358.80812689978 7872139.3294466175 0.7490361829836831 0.2822906864287719 5.7345370251780165e-09 8.241501638883335 -0.20988332046672498 DRHDDYYR ddPTM_PC-9_AZD4547_30min_R2 3 DRHDDYYR 8 1 F8WJN3;Q16630-3;Q16630;Q16630-2 F8WJN3 CPSF6 Cleavage and polyadenylation specificity factor subunit 6 0 ;; 101.72 0.005831800000000001 24588100.0 25680.300000000003 20486.3 33689.9 46506.8 40412.4 30426.4 29630.3 32154.100000000002 25894.5 30103.0 False True 33846.10121657731 27108.095843568663 33243.14991341039 35785.375782897376 34801.83582880094 28523.8323981041 32267.339298503037 27185.422672712182 27263.230405330512 29049.103132640073 1.165134120046111 0.933181851425545 1.1443778405694671 1.23189262055696 1.1980347782130663 0.9819178329830854 1.1107860766361113 0.9358437865906494 0.9385222766033378 1.0 14.826206001834453 -7.758408914942256 24.938629823716305 0.9528872500710018 1.1071300267178685 0.38274604409302493 0.0878903469000811 82.68042153195718 680423.3462141812 0.0459155838493989 0.025037399833840696 1.7441791277081455e-08 7.758408914942256 0.1542427766468667 DRHDDYYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DRHDDYYR 8 1 F8WJN3;Q16630-3;Q16630;Q16630-2 F8WJN3 CPSF6 Cleavage and polyadenylation specificity factor subunit 6 0 ; 101.72 0.005831800000000001 11735900.0 13404.1 15782.1 20440.5 17725.8 27704.0 16454.7 13495.0 18517.1 17637.0 10772.9 False True 15673.149386957364 17348.842587734696 20927.879041027936 16732.68089381897 22275.600074828024 15591.786565156162 12216.655904660836 18031.045745489202 17894.907759074125 12725.941491770523 1.231590558316861 1.363265939809142 1.6445053636747704 1.314848170930181 1.750408807806713 1.225197096437925 0.9599805179491807 1.4168732236549513 1.4061755486339627 1.0 13.635484773395625 -6.951476080424996 24.999943065891966 1.2107944965495452 1.4606044384288241 0.3014529392567822 0.19722000961537842 155.31210280402803 80017.57637406913 0.06987699255307121 0.06162570133164876 1.1182114104579905e-07 6.951476080424996 0.24980994187927896 DRHDDYYR ddPTM_PC-9_Lapatinib_30min_R1 3 DRHDDYYR 8 1 F8WJN3;Q16630-3;Q16630;Q16630-2 F8WJN3 CPSF6 Cleavage and polyadenylation specificity factor subunit 6 0 ;; 119.21 0.0044971 20217600.0 25017.2 17119.0 21870.0 18920.4 23289.0 19700.199999999997 18537.199999999997 16000.199999999999 24925.9 15217.5 False True 24660.45014040741 17079.362007288233 20071.933020641347 20311.86933260415 21919.186807935686 18857.66836940918 19496.96551278378 16743.62770360184 22118.482660636688 17847.82459895582 1.3817062131958737 0.9569436270842473 1.1246150985714891 1.1380585471347857 1.2281153193996572 1.0565807762651613 1.0924001076256902 0.9381326901084304 1.2392817140264099 1.0 14.12346062010317 -6.801097622385291 24.983630613974427 1.0631073176279946 1.1504408267930397 0.13891439098393166 0.12219564115925989 358.98909138826997 226151.19085078815 0.04118175877976377 0.03631946587981828 1.5808926401951944e-07 6.801097622385291 0.08733350916504512 DRHEASGFAR ddPTM_PC-9_AZD4547_30min_R2 1 DRHEASGFAR 10 1 H0Y6J6;Q5W012;Q96I25;Q5W011;Q5W010 H0Y6J6 RBM17 Splicing factor 45 0 88.134 0.013199 607660.0 616.3 825.64 1976.3 3978.8 2629.0 2322.7 928.35 2995.9 2172.1 1883.7 False True 812.2705801636499 1092.5119837298116 1950.0929707085204 3061.5491318472164 2264.008729843258 2177.4612018206685 1010.9713515477496 2532.952493933228 2286.9127715699633 1817.7522363536566 0.44685439738092936 0.6010235948994622 1.072804605439702 1.684249960263325 1.2454990754871937 1.197886685695172 0.5561656486121126 1.393453102835531 1.2580992754862046 1.0 10.827939855072424 -5.2585396691984245 3.6313846435311703 1.1951463957636719 0.4920629519040775 0.48517674128608546 0.2718690454533572 0.19465590802436708 5.663730346599492 0.07581615925105796 0.20635577040224207 5.5139183501115616e-06 5.2585396691984245 -0.7030834438595943 DRHEASGFAR ddPTM_PC-9_Lapatinib_30min_R1 2 DRHEASGFAR 10 1 H0Y6J6;Q5W012;Q96I25;Q5W011;Q5W010 H0Y6J6 RBM17 Splicing factor 45 0 ; 74.533 0.033374 1107840.0 3453.3 1752.96 5886.2 3326.7 3170.04 4001.5 1644.34 2289.8 5041.0 2104.37 False True 3404.055308742341 1748.9011288215404 5402.259357389077 3571.3566155458775 2983.5844797384334 3830.365172952092 1729.4758793825888 2396.1924673258764 4473.229495916678 2468.10755060323 1.379216763836064 0.7086000479979455 2.188826559064945 1.447002021720246 1.2088551323499723 1.551944189796718 0.7007295443668522 0.9708622570925741 1.8124127106306114 1.0 11.269189547602084 DRLGS(ph)YSGPTSVSR ddPTM_PC-9_AZD4547_30min_R2 2 DRLGSYSGPTSVSR 14 1 V9GYZ0;Q9BZ23-3;Q9BZ23-4;Q9BZ23;A0A2R8YFI4 V9GYZ0 PANK2 Pantothenate kinase 2, mitochondrial 1 DRLGS(0.855)YS(0.145)GPTSVSR;DRLGS(0.993)YS(0.006)GPTSVSR 157.07 0.0018195999999999998 41351000.0 65880.0 62755.0 86165.0 109460.0 99492.0 78272.0 77433.0 109345.0 63158.0 108321.0 True False 86828.4696108735 83039.32650908898 85022.3958007891 84225.68814014176 85679.25315692862 73377.6394665293 84324.38699240256 92448.242748132 66496.4029403876 104528.71476034657 0.8306661935903976 0.7944164117914737 0.8133879383834415 0.805766035995433 0.8196719279804197 0.7019854748502603 0.8067102631629351 0.8844291538462755 0.6361544107075667 1.0 16.67353978948688 -10.552786538645142 4.805158221160995 1.0000038710670585 0.7913509011144003 0.4779658567207462 0.06634922641458774 88653924.59155211 7.327751092932482 4462.615601391415 0.015180863209922641 2.8003573933052414e-11 10.552786538645142 -0.20865296995265814 DRLGS(ph)YSGPTSVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DRLGSYSGPTSVSR 14 1 V9GYZ0;Q9BZ23-3;Q9BZ23-4;Q9BZ23;A0A2R8YFI4 V9GYZ0 PANK2 Pantothenate kinase 2, mitochondrial 1 DRLGS(0.911)Y(0.004)S(0.084)GPT(0.001)SVSR;DRLGS(0.865)Y(0.001)S(0.133)GPT(0.001)SVSR 61.096000000000004 0.025162999999999998 37377000.0 72862.0 64191.0 94658.0 78270.0 92919.0 82678.0 87797.0 79373.0 66167.0 107969.0 True False 85196.09750990254 70563.45825646003 96915.00571246416 73884.7856547636 74712.18897462271 78342.22013369924 79480.23256476517 77289.54285264529 67134.5671993342 127542.92501786642 0.6679797997259992 0.5532526264908492 0.7598618715925494 0.5792934860511761 0.5857807398109844 0.6142419904728148 0.6231645742296678 0.6059884767564994 0.5263684143195703 1.0 16.960623347311085 -11.012796808491288 3.463823814663298 1.0065880582199702 0.6138052853790126 0.781513574445418 0.061404042811513425 30302786.064210624 45380236.15492631 1937582.7004958505 0.01481855908305766 9.709641418465886e-12 11.012796808491288 -0.39278277284095764 DRLGS(ph)YSGPTSVSR ddPTM_PC-9_Lapatinib_30min_R1 3 DRLGSYSGPTSVSR 14 1 V9GYZ0;Q9BZ23-3;Q9BZ23-4;Q9BZ23;A0A2R8YFI4 V9GYZ0 PANK2 Pantothenate kinase 2, mitochondrial 1 DRLGS(0.969)YS(0.03)GPTSVSR;DRLGS(0.971)Y(0.004)S(0.025)GPTSVSR;DRLGS(0.992)YS(0.008)GPTSVSR 170.42 0.00014367 53242000.0 138366.0 121777.0 112415.0 116719.0 155752.0 130806.0 129286.0 142735.0 154040.0 126388.0 True False 136392.87546678324 121495.0328384564 103172.67263444897 125302.90462316992 146590.97358021385 125211.73230367893 135979.79647874375 149366.98917973557 136690.39308688857 148233.99739857623 0.9201187167613499 0.8196165182793846 0.6960122134265532 0.8453047669371793 0.9889160122023521 0.8446897101951969 0.9173320484174559 1.0076432653847478 0.9221257976289416 1.0 17.17751684146885 -6.087083519298472 5.73692448333885 0.9397723710341195 0.8062141179867134 0.4577432865037927 0.06775700961880708 0.21253049319922582 10.997932572814333 0.020656424412025823 0.02705775202031614 8.183074040664613e-07 6.087083519298472 -0.1335582530474061 DRNT(ph)LPK ddPTM_PC-9_Lapatinib_30min_R1 1 DRNTLPK 7 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 DRNT(1)LPK 64.84100000000001 0.042069999999999996 8056300.0 57735.0 43270.0 46348.0 47907.0 40086.0 39633.0 38465.0 34890.0 39420.0 31725.0 True False 56911.68831269771 43169.810973500855 42537.44634845382 51430.24059306709 37728.22029210825 37937.98897903544 40456.52948930952 36511.11677220713 34980.1044889973 37208.62397909471 1.5295295075860094 1.160209821189716 1.1432147120611893 1.3822129144566768 1.0139644054911967 1.019602041729641 1.087289051915481 0.9812541520675566 0.9401074468287384 1.0 15.183349418353824 -1.5228787464370706 0.29030876097692326 0.9592782925842127 4.8626814981068955 0.6638813467717157 0.10479049556402967 34.23373409161422 0.4858637430240496 0.11410223528610623 68.62044665098821 0.029999999920095714 1.5228787464370706 3.903403205522683 DRNVAT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DRNVATPR 8 1 P11216;P11217-2;P11217 P11216 PYGB;PYGM Glycogen phosphorylase, brain form;Glycogen phosphorylase, muscle form 1 DRNVAT(1)PR 63.565 0.041461000000000005 3591100.0 17579.0 20478.0 36150.0 32488.0 38034.0 32891.0 30507.0 28886.0 29490.0 21749.0 True False 20554.777498923722 22510.920505612776 37011.95309963845 30667.80268751711 30581.510729353497 31166.13805870369 27617.15610844669 28127.7731072469 29921.235460401196 25691.92153501072 0.8000482747432284 0.8761867217653163 1.4406066533093593 1.193674931854579 1.1903162123424544 1.2130715102890683 1.0749354060891252 1.0948100191305976 1.164616489258195 1.0 14.649027175018242 -5.087003314375783 8.207026021900019 1.1741805379849404 0.8186509988663996 0.6001481404224291 0.10959557257155435 0.17958120604777816 15.231370006019306 0.02795427361690515 0.07491466821501476 8.18458541936334e-06 5.087003314375783 -0.3555295391185408 DRNVIPDT(ph)PPSTPLVPSR ddPTM_PC-9_AZD4547_30min_R2 2 DRNVIPDTPPSTPLVPSR 18 1 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 DRNVIPDT(0.998)PPS(0.001)T(0.001)PLVPSR;DRNVIPDT(0.999)PPSTPLVPSR 88.04 0.00114 48460000.0 110000.0 113287.0 141521.0 214681.0 176876.0 163010.0 121236.0 168688.0 123373.0 131871.0 True False 144977.71185786414 149904.80730197096 139644.33907182136 165189.61223838633 152319.8205019993 152816.95893089395 132025.7691347478 142621.1456646112 129894.24490902851 127254.23642840826 1.139276113132995 1.1779946311359595 1.0973649521710316 1.298106977611862 1.1969724920528884 1.2008791472876974 1.0374960617442701 1.120757545426381 1.0207459378541435 1.0 16.9573541603843 -7.2606731770685915 24.996683215072633 1.0548130106311442 1.1864646389280544 0.595471445608673 0.05642078463987104 53.82363203342517 1755993.233806837 0.022710627032529393 0.01653210910403443 5.48689719244701e-08 7.2606731770685915 0.13165162829691024 DRNVIPDT(ph)PPSTPLVPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DRNVIPDTPPSTPLVPSR 18 1 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 DRNVIPDT(0.988)PPS(0.006)T(0.006)PLVPSR;DRNVIPDT(0.999)PPSTPLVPSR;DRNVIPDT(0.999)PPSTPLVPSR 154.95 1.2141e-05 28824900.0 63674.0 50904.0 68346.0 75602.0 97996.0 98114.0 105228.0 104767.0 94536.0 81059.0 True False 74452.75058117461 55957.41270718392 69975.62784364847 71366.26504499107 78794.38727017194 92968.72912017436 95260.04205525391 102016.97725981231 95918.41015545893 95754.3550373092 0.7775390534682757 0.5843850411334396 0.7307827180955222 0.7453056836650856 0.822880455301181 0.9709086243017411 0.9948376971275856 1.0654030014620532 1.0017132914538018 1.0 16.547050483796937 -6.577106294166634 1.296451044198034 1.0272987184533262 0.685614280592307 0.8920567288542748 0.04933343253379784 0.1208830275581514 0.42406028416811326 0.021009392405329803 0.022423210366791308 2.647851993906764e-07 6.577106294166634 -0.3416844378610192 DRNVIPDT(ph)PPSTPLVPSR ddPTM_PC-9_Lapatinib_30min_R1 1 DRNVIPDTPPSTPLVPSR 18 1 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 DRNVIPDT(0.999)PPS(0.001)T(0.001)PLVPSR 74.812 0.0044108 18167000.0 63058.0 55465.0 68962.0 60946.0 64060.0 72604.0 59236.0 50868.0 82967.0 55474.0 True False 62158.78135657907 55336.57420025944 63292.21056101819 65428.172149896 60292.11674680572 69498.89616819042 62302.950236025965 53231.51298276388 73622.38277875805 65062.60698554131 0.9553687476800992 0.8505127102047532 0.9727893408126645 1.005618667638632 0.9266784646395168 1.068184928151357 0.9575845961701379 0.8181583162598046 1.131562139757464 1.0 15.989541010255575 -5.386472506092829 7.897012859647424 0.979649465218067 0.9032862749422107 0.13676442719511783 0.08178170380083237 0.532644605743261 31.538405148776945 0.020616251125524895 0.04310354111533517 4.107026394288003e-06 5.386472506092829 -0.07636319027585625 DRPFFAGLVK ddPTM_PC-9_AZD4547_30min_R2 2 DRPFFAGLVK 10 1 Q32Q12;P22392-2;J3KPD9;E7ERL0;E5RHP0;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Nucleoside diphosphate kinase A 0 ; 137.95 0.00015329 6676700.0 24823.0 24471.3 31022.0 34109.0 32220.0 30446.0 26292.0 30231.0 28301.0 28537.0 False True 32716.197649525046 32381.16916264634 30610.62801058527 26245.697028796785 27746.809157683427 28542.206807005652 28631.937065647027 25559.493589270496 29796.933082363405 27537.928315986785 1.1880413542413095 1.1758752797627072 1.1115806410467948 0.9530744915753226 1.0075852053683856 1.0364689195024104 1.0397273439420325 0.9281560070890397 1.0820324877185907 1.0 14.749132408859884 -5.556016434086456 4.064752343876976 1.0066407351908346 1.176438817241474 0.7486860954526402 0.04148962995752998 0.09661048369283486 3.5190817304022524 0.011157493057107856 0.021348254552490495 2.7796080829463204e-06 5.556016434086456 0.1697980820506393 DRPFFAGLVK ddPTM_PC-9_Lapatinib_30min_R1 2 DRPFFAGLVK 10 1 Q32Q12;P22392-2;J3KPD9;E7ERL0;E5RHP0;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Nucleoside diphosphate kinase A 0 ; 125.75 0.00047855 10464500.0 50501.0 50885.0 50909.0 47926.0 55777.0 46279.0 57212.0 44903.0 47195.0 51645.0 False True 49780.846479250824 50767.17890886505 46723.458534422956 51450.637916449276 52496.30652180121 44299.755051618115 60174.15741953404 46989.35730646074 41879.40211461765 60571.76943736314 0.8218489725767193 0.8381326710517025 0.7713735122553976 0.8494161289056288 0.866679428542818 0.7313597648394305 0.9934356875897399 0.7757633257693111 0.6914013327268714 1.0 15.886357935916427 DRPFFPGLVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DRPFFPGLVK 10 1 Q32Q12;P22392-2;J3KPD9;P22392;F6XY72;O60361 Q32Q12 NME1-NME2;NME2;NME2P1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Putative nucleoside diphosphate kinase 0 114.4 0.0015695 6867400.0 47078.0 43355.0 42699.0 53278.0 47777.0 39630.0 42047.0 32604.0 38176.0 32223.0 False True 55047.375567115894 47658.99787678685 43717.10609685924 50293.00638960652 38415.439820064224 37551.7330353722 38064.00376608182 31748.179546793504 38734.25177810364 38064.77482287236 1.4461500382773587 1.2520499096227287 1.148492439539942 1.3212479680659102 1.0092123229107126 0.9865218751486773 0.9999797435609661 0.8340566756148696 1.017587834378282 1.0 15.216168923326629 -5.976218246922771 0.6958573009921496 0.9323789993232396 1.3955771582130687 0.7547136819347335 0.08760140979312724 0.4629706736848428 0.43076011342049364 0.049845517404018776 0.13449278103542692 1.0562865579010641e-06 5.976218246922771 0.46319815888982907 DRPFFPGLVK ddPTM_PC-9_Lapatinib_30min_R1 2 DRPFFPGLVK 10 1 Q32Q12;P22392-2;J3KPD9;P22392;F6XY72;O60361 Q32Q12 NME1-NME2;NME2;NME2P1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Putative nucleoside diphosphate kinase 0 ; 109.79 0.0023761 20962000.0 144814.0 129705.0 134766.0 141417.0 122314.0 111132.0 102849.0 92550.0 111317.0 94479.0 False True 142748.92580436484 129404.67604155176 123686.05969180408 151817.27793328252 115119.73099857628 106379.14342134504 108174.01797597815 96850.21087038578 98779.3072400231 110809.56926464586 1.2882364470115248 1.1678113803736148 1.116203776556566 1.3700737124128528 1.0388970173111718 0.9600176602733681 0.9762154901769066 0.8740238908345449 0.8914330043473867 1.0 16.7577229490958 -6.487263035827716 4.548626262650869 0.9389019658119568 1.2226117568692327 0.7844557225792734 0.07287607537369609 0.09812935408472029 4.740285992926392 0.024026176742733014 0.026277397832531166 3.256394137223217e-07 6.487263035827716 0.2837097910572759 DRPGS(ph)PESPLLDAPFSR ddPTM_PC-9_AZD4547_30min_R2 2 DRPGSPESPLLDAPFSR 17 1 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 DRPGS(1)PESPLLDAPFSR;DRPGS(0.996)PES(0.004)PLLDAPFSR 84.324 0.0016157 59006000.0 45492.0 40182.0 66097.0 72057.0 81850.0 69026.0 51647.0 69374.0 61443.0 55272.0 True False 59957.50970761767 53170.045698162976 65220.51059298733 55445.37191955238 70486.54033384219 64709.793308164364 56243.4829465036 58653.842355927685 64690.75154162936 53336.94410348743 1.1241272014250503 0.9968708667485593 1.2228017875647827 1.0395303452701388 1.3215331609002592 1.2132264867407978 1.0544939139628384 1.0996850933590065 1.2128694777884652 1.0 15.702847548775766 -5.258185118869298 24.99724644941443 1.1507460635702154 1.0604990407950365 0.10454377082419875 0.09858269982637068 594.1549179159415 4563895.828015039 0.024910367924722888 0.06012950964615911 5.518421653428827e-06 5.258185118869298 -0.09024702277517882 DRPGS(ph)PESPLLDAPFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DRPGSPESPLLDAPFSR 17 1 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 DRPGS(0.999)PES(0.001)PLLDAPFSR;DRPGS(0.998)PES(0.002)PLLDAPFSR;DRPGS(0.997)PES(0.003)PLLDAPFSR;DRPGS(0.999)PES(0.001)PLLDAPFSR;DRPGS(0.997)PES(0.003)PLLDAPFSR;DRPGS(0.956)PES(0.044)PLLDAPFSR 130.01 1.3695e-05 68756800.0 59964.9 64537.6 68698.5 75469.9 84722.7 67401.4 71534.4 66498.6 58420.7 47199.100000000006 True False 70115.77320923889 70944.46641386047 70336.53278051218 71241.56617971697 68121.89512199078 63866.75193061651 64758.14376779318 64753.08221109083 59274.992216394065 55755.92320212999 1.2575484214484376 1.272411294431768 1.2615078137173628 1.2777398720750694 1.2217875915179606 1.1454702615017711 1.1614576541586041 1.1613668735489098 1.0631156083902784 1.0 15.766837456697482 -7.7487362527643535 0.4179654072021106 0.9929338446815397 1.2898967752941213 0.9265415993203744 0.024301090870624247 0.2743311433367665 0.12661369431629416 0.02989527714552276 0.02491593584322427 1.7834615356307143e-08 7.7487362527643535 0.2969629306125816 DRPGS(ph)PESPLLDAPFSR ddPTM_PC-9_Lapatinib_30min_R1 2 DRPGSPESPLLDAPFSR 17 1 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 DRPGS(0.998)PES(0.002)PLLDAPFSR;DRPGS(0.996)PES(0.004)PLLDAPFSR 80.016 0.0028388000000000003 59787000.0 31341.0 26950.0 22230.0 22521.0 23807.0 19762.2 18136.6 18356.3 24846.0 14196.8 True False 30894.071592764503 26887.59893080308 20402.33521028152 24177.269467853635 22406.719066362846 18917.01677393825 19075.624404934653 19209.200710967776 22047.581840020994 16650.69796395308 1.8554220165212745 1.614803114500771 1.2253141132251824 1.4520273876923808 1.3456924817728912 1.1361095381641957 1.1456351226976353 1.1536573873692004 1.324123582552009 1.0 14.023295033003878 -1.522878745280338 0.43086361035187576 1.1509116788416194 15.404611319984761 0.7967735396976886 0.10993296213282902 35.91429044512371 0.45059820066210804 0.07321031493660342 444.6433083605554 0.029999999999999964 1.522878745280338 14.253699641143141 DRPPCS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 1 DRPPCSPSR 9 1 O95758-1;O95758-6;O95758-2;O95758;O95758-5;O95758-4;X6R242;B1ALY4 O95758-1 PTBP3 Polypyrimidine tract-binding protein 3 1 DRPPCS(0.999)PS(0.001)R 74.69800000000001 0.012763 28038000.0 12778.0 17146.0 18639.0 26502.0 22796.0 21556.0 13721.0 21671.0 15948.0 16155.0 True False 16841.13820108896 22688.109191695345 18391.83468149375 20392.373351818365 19631.168887602467 20208.099912363337 14942.142418900916 18322.244900039044 16790.978721512707 15589.418367199294 1.0802929143606366 1.4553531541261318 1.179764007115932 1.308090710730085 1.2592624320678418 1.2962702928597976 0.9584797884659847 1.1753000957745618 1.0770753806210975 1.0 13.92827948241449 -7.246370828096879 24.926204830377515 1.0673221560263915 1.2699805022322408 0.4913470076348616 0.10434325232068689 643.7522394228914 1064888.1640009214 0.03719310770783378 0.028689733667163916 5.670602067629551e-08 7.246370828096879 0.20265834620584933 DRPPCS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 1 DRPPCSPSR 9 1 O95758-1;O95758-6;O95758-2;O95758;O95758-5;O95758-4;X6R242;B1ALY4 O95758-1 PTBP3 Polypyrimidine tract-binding protein 3 1 DRPPCS(0.553)PS(0.447)R 54.005 0.045799 23867000.0 27181.0 27095.0 29396.0 30459.0 32359.0 22253.0 16374.0 26337.0 29092.0 16701.0 True False 26793.393955615058 27032.263192211838 26979.174351841466 32699.05646824539 30455.707240241773 21301.291064276633 17221.76560140269 27560.713167945516 25815.352607658788 19587.74559731633 1.3678651186528559 1.3800599491099916 1.3773496402535377 1.6693629343810454 1.5548347352650136 1.0874804840836338 0.8792112147792139 1.4070385502516196 1.3179338316092735 1.0 14.257663743324983 -6.764012190447455 24.99892756189112 1.1475775934269794 1.4708438852476629 0.5060829736587391 0.16364732101062668 64.8965892085872 630567.0158645819 0.06098373252127822 0.05625008842308318 1.7218202436010347e-07 6.764012190447455 0.32326629182068345 DRPPCSPS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DRPPCSPSR 9 1 O95758-1;O95758-6;O95758-2;O95758;O95758-5;O95758-4;X6R242;B1ALY4 O95758-1 PTBP3 Polypyrimidine tract-binding protein 3 1 DRPPCS(0.326)PS(0.674)R 80.834 0.008545299999999999 95078000.0 4963.5 4467.3 4924.1 7766.3 7452.5 5572.9 4981.6 7085.5 4898.5 6897.5 True False 5803.722516406386 4910.784020642833 5041.50921875324 7331.179389684321 5992.23612321888 5280.647313470239 4509.706784339268 6899.513132707809 4970.131295448468 8147.962149420042 0.7122912956609015 0.6027008877296238 0.6187448010067261 0.8997561912098649 0.7354275846317471 0.6480942371395413 0.5534766487176503 0.846777759417906 0.6099845831760808 1.0 12.992223563079433 -10.962660136846802 3.600803121601687 1.002942101823243 0.6937276492594633 0.4356315166774084 0.10518057872007844 66361799.48836849 56704019.09371157 1819768.5913711109 0.02751171299847136 1.0897825841588422e-11 10.962660136846802 -0.30921445256377966 DRPPCSPS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 DRPPCSPSR 9 1 O95758-1;O95758-6;O95758-2;O95758;O95758-5;O95758-4;X6R242;B1ALY4 O95758-1 PTBP3 Polypyrimidine tract-binding protein 3 1 DRPPCS(0.123)PS(0.877)R 59.898 0.034104 22936000.0 36353.0 25847.0 36106.0 30443.0 28143.0 31080.0 27294.0 25523.0 35860.0 21416.0 True False 35834.59955367627 25787.152859534937 33137.50405319049 32681.87977487095 26487.68407126686 29750.78085101864 28707.149769432337 26708.89175629241 31821.069177459245 25117.72706497373 1.4266656955456392 1.0266515275378842 1.31928752818563 1.3011479776944193 1.0545414401052042 1.1844535444652406 1.1429039616193617 1.063348275391428 1.2668769389501497 1.0 14.61641829837877 -1.5228788456999705 0.05680799131227207 0.7586211958613134 2.0100357569848577 0.268824801937939 0.1175889254075513 551.7922833701915 2.3590288218764064 11.062928170351563 58.08417078905796 0.02999999306325831 1.5228788456999705 1.2514145611235443 DRPQEADGIDSVIVVDNVPQVGPDR ddPTM_PC-9_AZD4547_30min_R2 1 DRPQEADGIDSVIVVDNVPQVGPDR 25 1 P55884;P55884-2;C9JZG1 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 0 129.9 2.668e-07 2111000.0 13499.0 16807.0 20632.0 17180.0 19400.0 22253.0 20011.0 23393.0 14480.0 17249.0 False True 17791.401203357327 22239.534071201662 20358.40619929068 13219.416428354074 16706.644868375504 20861.516392179503 21791.940233556325 19778.149367662474 15245.383238494107 16645.117760186997 1.0688660458691435 1.3360995333055437 1.2230857415731473 0.7941918236212925 1.0036964057013567 1.2533114329823245 1.3092091355268072 1.1882252593591913 0.9159072022283389 1.0 14.022811456782616 -8.26104830640598 24.993575524364054 0.9579535911204377 1.1483216750796617 0.19546469120906373 0.15346776065129183 61.947056202445964 3959783.002697784 0.1316587942128483 0.042710839233532055 5.4821598367922835e-09 8.26104830640598 0.190368083959224 DRPQEADGIDSVIVVDNVPQVGPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DRPQEADGIDSVIVVDNVPQVGPDR 25 1 P55884;P55884-2;C9JZG1 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 0 57.802 0.0061975 3835400.0 6173.9 9862.0 10841.0 9231.1 12072.0 7119.8 12347.0 7102.1 9122.3 9005.5 False True 7219.019329916669 10841.034184312584 11099.49055472145 8713.911394629991 9706.578259577094 6746.425154308428 11177.402775461082 6915.677400296966 9255.69637980393 10638.125862501223 0.6785987892250169 1.0190736906513393 1.0433689822985184 0.819120915399772 0.9124331094626563 0.6341742184202939 1.050692849467102 0.6500841867903 0.8700495274670254 1.0 13.376956390630202 DRPVS(ph)QPSLVGSK ddPTM_PC-9_AZD4547_30min_R2 2 DRPVSQPSLVGSK 13 1 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;F6UYG0 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 DRPVS(1)QPSLVGSK;DRPVS(1)QPSLVGSK 119.08 0.00011018 52652000.0 82295.0 87205.0 100753.0 94056.0 99760.0 100028.0 122402.0 166050.0 144978.0 113991.0 True False 108463.09815766293 115392.31086327968 99416.94938915924 72372.84235071429 85910.0459829456 93773.23334727573 133295.54087590624 140390.7879494019 152641.2411015469 110000.20978615993 0.9860262845726827 1.0490190072146406 0.9037887253344833 0.6579336756848634 0.7809989285470861 0.8524823137116794 1.2117753332928398 1.276277456400503 1.3876449999348275 1.0 16.74714674961551 -7.285881712354943 5.577546830634663 1.2453688817707675 0.8667713857240759 0.6118350801742255 0.13491289615353425 0.12779266795075878 12.98379186358269 0.06048858587211359 0.04174054043862198 5.177478303619567e-08 7.285881712354943 -0.3785974960466917 DRPVS(ph)QPSLVGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DRPVSQPSLVGSK 13 1 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;F6UYG0 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 DRPVS(1)QPSLVGSK 98.882 0.0012489 20295000.0 33765.0 40662.0 47561.0 41312.0 51554.0 42009.0 49918.0 51144.0 43051.0 34498.0 True False 39480.74761085153 44698.65463420383 48695.03461609694 38997.42257531111 41452.363783485554 39805.97408738205 45189.405664976606 49801.52419154728 43680.539430509765 40752.21431398228 0.9688000584867728 1.0968398990497923 1.1949052446799056 0.9569399658837902 1.0171806484945543 0.9767806426588316 1.1088822147627915 1.2220568877029128 1.0718568344278354 1.0 15.314590831359649 -7.489866962088423 22.360575164503906 1.1212679530836656 1.0410777785116907 0.10725119461977284 0.08431282388446461 328.24142814999453 222335.59260288303 0.036060463469824104 0.024277240387440658 3.236927989187542e-08 7.489866962088423 -0.08019017457197486 DRPVS(ph)QPSLVGSK ddPTM_PC-9_Lapatinib_30min_R1 2 DRPVSQPSLVGSK 13 1 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;F6UYG0 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 DRPVS(1)QPSLVGSK;DRPVS(1)QPSLVGSK 122.97 8.194e-05 64004000.0 123623.0 130772.0 119688.0 118821.0 136940.0 110923.0 113224.0 114818.0 127729.0 169133.0 True False 121860.1133503186 130469.20546860783 109847.7146490408 127559.49271523616 128885.45843439862 106179.08186414235 119086.18471071326 120152.86344371698 113342.81497400157 198367.41369444353 0.614315179498315 0.6577149091109131 0.5537588689755537 0.6430466090147408 0.649731001851585 0.5352647387322191 0.6003313875642317 0.6057086756638124 0.5713781959600979 1.0 17.59781552454359 -11.301312084723326 2.6765319206578417 1.101049342990542 0.6040972014285845 0.904516569009795 0.03864962368750605 25550479.71147955 19544749.380632833 16920086.748388845 0.009479054458783765 4.996753384193198e-12 11.301312084723326 -0.49695214156195744 DRQLS(ph)QEVTPADLECGLEGQAGSVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DRQLSQEVTPADLECGLEGQAGSVQR 26 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 DRQLS(0.57)QEVT(0.429)PADLECGLEGQAGSVQR 44.474 0.021443 2592100.0 3823.7 2991.5 3315.8 5113.1 3298.7 3811.3 3222.1 4595.9 1718.1 3763.1 True False 4470.9768884825435 3288.4763498652514 3394.8612472415275 4826.629583893861 2652.3434149160853 3611.4287185898083 2916.8793620161287 4475.262494758569 1743.223962174138 4445.320241316789 1.0057716082920842 0.7397614055564964 0.7636932915851985 1.085777699215686 0.5966596940000009 0.8124113725314048 0.6561685556206617 1.0067356797297713 0.3921481170179455 1.0 12.118071639356632 -6.278575643703076 24.966807966013214 0.7433843112385133 0.8777476555215055 0.12660867242511986 0.19600692025764707 1919.235332699409 2796237.9668932743 0.057239834838991394 0.06506163764576003 5.265314977232998e-07 6.278575643703076 0.13436334428299213 DRS(ph)FSENGDR ddPTM_PC-9_Lapatinib_30min_R1 1 DRSFSENGDR 10 1 P47974 P47974 ZFP36L2 Zinc finger protein 36, C3H1 type-like 2 1 DRS(0.978)FS(0.022)ENGDR 62.732 0.027473 4361500.0 11055.0 9734.9 7610.5 10820.0 10619.0 13437.0 14288.0 12834.0 18721.0 14498.0 True False 10897.35367276129 9712.359437160469 6984.794067379562 11615.738894461898 9994.411297757259 12862.330833176879 15027.762728279075 13430.314492820471 16612.44383913036 17003.959982629316 0.6408715195691866 0.5711822097371609 0.41077455336962665 0.6831196325049078 0.5877696317779635 0.7564314928003013 0.8837801749493024 0.7898345154034964 0.9769750020642888 1.0 14.053583148383343 -7.16979401432211 0.7586751924655576 0.9720663730095508 0.543666636978794 0.8043080276978332 0.07904993137343433 0.2902372298665971 0.33537616070460136 0.06406593140380812 0.04291020428551987 6.764037173016969e-08 7.16979401432211 -0.42839973603075676 DRS(ph)PAAETPPLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DRSPAAETPPLQR 13 1 B4DKV7;Q8TE68-2;Q8TE68;K7EKX9;K7EN83;Q8TE68-3 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 DRS(1)PAAETPPLQR;DRS(0.999)PAAET(0.001)PPLQR 137.21 0.00028321 29241000.0 43513.0 47904.0 41482.0 44824.0 47206.0 32946.0 44189.0 37126.0 38384.0 34889.0 True False 50878.89147907548 52659.59253349319 42471.08820136103 42312.65660136871 37956.32317110641 31218.25376188173 40003.098019344754 36151.48183824858 38945.29338460631 41214.09951882794 1.2345020775191835 1.2777081908446544 1.0304989966348497 1.0266548849875736 0.9209548095007323 0.7574653850588248 0.9706168152738612 0.8771629675357436 0.9449507289808633 1.0 15.330850353513076 -5.510760858619118 1.3723149051093873 0.9043967323232277 1.2822956003172776 0.7727693349812153 0.07032444638202913 0.22024901314199144 0.7569337912640581 0.022304196821545136 0.07913896855889953 3.0848861547891915e-06 5.510760858619118 0.3778988679940499 DRS(ph)PAAETPPLQR ddPTM_PC-9_Lapatinib_30min_R1 1 DRSPAAETPPLQR 13 1 B4DKV7;Q8TE68-2;Q8TE68;K7EKX9;K7EN83;Q8TE68-3 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 DRS(1)PAAETPPLQR 134.81 0.00023259 17036000.0 16674.0 15715.0 17846.0 13695.0 17512.0 16399.0 15099.0 15615.0 17277.0 13428.0 True False 16436.2257023629 15678.612883026723 16378.770767552143 14702.17598518074 16481.978589916678 15697.652997936122 15880.752340025605 16340.52990536011 15331.082325124467 15749.011908314682 1.0436353593513636 0.9955299401830542 1.0399871981114561 0.9335300570455938 1.0465404868488941 0.996738912213823 1.0083649966409238 1.037559054529201 0.9734631235519247 1.0 13.942973696435542 DRS(ph)SPPPGYIPDELHQVAR ddPTM_PC-9_AZD4547_30min_R2 2 DRSSPPPGYIPDELHQVAR 19 1 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 DRS(0.5)S(0.5)PPPGYIPDELHQVAR;DRS(0.499)S(0.499)PPPGY(0.001)IPDELHQVAR 140.89 2.814e-05 132841000.0 64801.0 61732.0 79111.0 97595.0 79189.0 77779.0 63081.0 85143.0 70357.0 74323.0 True False 85406.37005546752 81685.66176494448 78061.9364497909 75095.98057771917 68194.97425163838 72915.46683446398 68695.08679591064 71986.10574149898 74075.92738333771 71720.97439216063 1.1908144134863115 1.1389368655018306 1.0884115436435475 1.0470574502669814 0.9508372526948317 1.0166547157568164 0.9578102832275418 1.003696705902079 1.0328349274551196 1.0 16.13010746816272 -5.486244851479577 1.2852905456392154 0.9928979867391964 1.188514519866302 0.8728120417521869 0.02598128477620944 0.18149649542983692 0.5287338711237569 0.008525489162051742 0.03343866893481727 3.264037566669982e-06 5.486244851479577 0.1956165331271057 DRS(ph)SPPPGYIPDELHQVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DRSSPPPGYIPDELHQVAR 19 1 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 DRS(0.5)S(0.5)PPPGY(0.001)IPDELHQVAR;DRS(0.5)S(0.5)PPPGYIPDELHQVAR;DRS(0.5)S(0.5)PPPGYIPDELHQVAR;DRS(0.5)S(0.5)PPPGYIPDELHQVAR;DRS(0.499)S(0.499)PPPGY(0.002)IPDELHQVAR;DRS(0.5)S(0.5)PPPGYIPDELHQVAR 160.09 3.1367e-06 149888800.0 159914.7 156642.6 170441.0 180337.0 200732.0 177023.0 192934.0 165143.0 161285.0 143607.1 True False 186985.10025070512 172193.0421131212 174504.95984109238 170233.30255044263 161400.00556671855 167739.6022488187 174657.89479880183 160808.17123347166 163643.48800375746 169641.9304368216 1.1022339805331471 1.0150382141356833 1.0286664351893937 1.0034860020284977 0.9514157564177653 0.9887862146869911 1.0295679514437517 0.9479270297113258 0.9646405672370129 1.0 17.37213327969544 -1.5228787484115025 0.6322047805418433 0.9804008749908965 10.151563949512683 0.6574391783015208 0.02533237498052451 126.65087711709458 0.873765314176256 0.011231450908875935 1618.7409309520976 0.02999999978370679 1.5228787484115025 9.171163074521786 DRS(ph)SPPPGYIPDELHQVAR ddPTM_PC-9_Lapatinib_30min_R1 3 DRSSPPPGYIPDELHQVAR 19 1 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 DRS(0.5)S(0.5)PPPGYIPDELHQVAR;DRS(0.5)S(0.5)PPPGYIPDELHQVAR;DRS(0.493)S(0.493)PPPGY(0.015)IPDELHQVAR 137.52 1.0813e-05 121555200.0 98450.0 84529.0 92528.0 78652.0 87431.0 88834.0 78228.0 81468.0 84498.0 69360.0 True False 97046.08494648125 84333.27829394619 84920.70500840871 84436.33045538045 82288.48047595964 85034.77690216833 82278.26306745627 85253.3006935561 74980.94543661321 81348.78358360952 1.1929629512743505 1.0366876378338126 1.0439087257048902 1.0379544319626806 1.0115514559770191 1.0453109826131621 1.0114258559612197 1.0479972402529358 0.9217217779236797 1.0 16.311833152847193 -1.8770970633412036 1.1540724364252546 1.0151375687375908 199.99999627121156 0.6938129196882074 0.035206186145701764 941.4386443883185 1.5079957029012203 0.010145453258539692 495634.0791267262 0.013270978227279098 1.8770970633412036 198.98485870247396 DRS(ph)SSAPNVHINTIEPVNIDDLIR ddPTM_PC-9_AZD4547_30min_R2 5 DRSSSAPNVHINTIEPVNIDDLIR 24 1 H7C560;P15056;A0A2R8Y679;A0A2R8Y492;A0A2R8YDP5;A0A2R8Y8E0;A0A2U3TZI2 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 DRS(0.341)S(0.341)S(0.316)APNVHINT(0.002)IEPVNIDDLIR;DRS(0.333)S(0.333)S(0.333)APNVHINTIEPVNIDDLIR;DRS(0.333)S(0.333)S(0.333)APNVHINTIEPVNIDDLIR;DRS(0.333)S(0.333)S(0.333)APNVHINTIEPVNIDDLIR;DRS(0.333)S(0.333)S(0.333)APNVHINTIEPVNIDDLIR 109.32 3.4326e-07 18352900.0 39142.4 31739.800000000003 56904.200000000004 81800.9 67878.09999999999 51100.5 41540.0 53660.2 42453.0 54878.0 True False 51588.86898750233 41999.0696443819 56149.613127456214 62942.9663163067 58454.397476292725 47905.17765688081 45236.979526357005 45368.24907872619 44696.97891048277 52956.73792356322 0.9741700680650827 0.7930826423825914 1.0602921427770255 1.1885733295573724 1.1038141654545401 0.9046096783005454 0.8542251902232201 0.8567039975953559 0.844028175885712 1.0 15.692526636014007 -6.905395961896248 6.934097629643224 0.8772122178149938 1.021906361805158 0.286138116398297 0.10381759457437464 0.31188186261030626 19.49438513603002 0.04104062064222191 0.03618084834296652 1.2433804601494406e-07 6.905395961896248 0.14469414399016423 DRS(ph)SSAPNVHINTIEPVNIDDLIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 DRSSSAPNVHINTIEPVNIDDLIR 24 1 H7C560;P15056;A0A2R8Y679;A0A2R8Y492;A0A2R8YDP5;A0A2R8Y8E0;A0A2U3TZI2 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 DRS(0.333)S(0.333)S(0.333)APNVHINTIEPVNIDDLIR;DRS(0.333)S(0.333)S(0.333)APNVHINTIEPVNIDDLIR;DRS(0.33)S(0.33)S(0.33)APNVHINT(0.01)IEPVNIDDLIR;DRS(0.333)S(0.333)S(0.333)APNVHINTIEPVNIDDLIR;DRS(0.333)S(0.333)S(0.333)APNVHINTIEPVNIDDLIR 78.378 8.8786e-05 15343400.0 35428.0 29625.699999999997 33618.799999999996 40645.3 43201.4 40370.3 39417.5 36679.8 37850.700000000004 29112.5 True False 41425.26066510438 32566.743706569596 34420.39969200899 38368.07561484052 34736.39579384476 38253.21040014855 35683.58904201322 35716.99411546057 38404.19488101079 34390.36579557682 1.2045600477571066 0.9469728789787466 1.0008733229710525 1.1156634925870808 1.0100618295346089 1.1123234520834482 1.0376042306186442 1.0385755803753147 1.1167137653985122 1.0 15.06971684082439 -5.734896390617713 24.9928430017998 1.062141411929065 1.0404192320945882 0.0 0.0730277810737201 1299.7059881061757 1223789.6736263589 0.018898041106657732 0.032721514418224476 1.8412112057644033e-06 5.734896390617713 -0.021722179834476885 DRS(ph)SSAPNVHINTIEPVNIDDLIR ddPTM_PC-9_Lapatinib_30min_R1 4 DRSSSAPNVHINTIEPVNIDDLIR 24 1 H7C560;P15056;A0A2R8Y679;A0A2R8Y492;A0A2R8YDP5;A0A2R8Y8E0;A0A2U3TZI2 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 DRS(0.328)S(0.328)S(0.328)APNVHINT(0.017)IEPVNIDDLIR;DRS(0.332)S(0.332)S(0.332)APNVHINT(0.004)IEPVNIDDLIR;DRS(0.333)S(0.333)S(0.333)APNVHINTIEPVNIDDLIR;DRS(0.333)S(0.333)S(0.333)APNVHINTIEPVNIDDLIR 128.67 1.6037e-07 17830100.0 68662.9 44373.1 64177.8 49420.7 51349.1 48849.5 39051.8 45559.4 52997.0 32321.8 True False 67683.75445476611 44270.35681322515 58901.34901747216 53055.26314062227 48328.84689421486 46760.32075874629 41073.71112207509 47676.25604676679 47027.91977684905 37908.580063908674 1.7854468392290233 1.167818914308882 1.5537735498974785 1.3995581752515753 1.2748788483435425 1.2335023015875244 1.0834937909262345 1.2576639896928652 1.2405613636165327 1.0 15.210236798254718 -1.5228787452803534 0.18382211409281718 1.0281071183244421 3.489779765342817 0.5628243401694154 0.14405738645776855 44.521167919310635 0.5089408077447359 0.3067155337234476 30.790556607485954 0.029999999999998906 1.5228787452803534 2.461672647018375 DRS(ph)VSVDSGEQR ddPTM_PC-9_AZD4547_30min_R2 1 DRSVSVDSGEQR 12 1 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 DRS(0.95)VS(0.047)VDS(0.003)GEQR 103.3 0.010327 6858200.0 6036.9 6888.1 9654.9 14882.0 12769.0 10271.0 7567.9 11328.0 9412.4 7451.7 True False 7956.5086246794435 9114.54362086299 9526.869717600412 11451.184824607994 10996.24475898386 9628.75274632974 8241.42843903508 9577.517891543643 9909.92024820455 7190.818251120961 1.106481675216742 1.2675252387921423 1.3248658754676894 1.5924731267992893 1.5292063260352435 1.3390343643894398 1.1461044002538017 1.3319093261814292 1.3781352694680766 1.0 12.811940230523797 -7.017752480142717 23.82454971058794 1.2418210442111512 1.375738067510652 0.1597448201718673 0.15863800088306132 914.8975682982702 1227827.3310120853 0.06380448823545483 0.05056759249176814 9.599475838757786e-08 7.017752480142717 0.13391702329950084 DRS(ph)VSVDSGEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DRSVSVDSGEQR 12 1 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 DRS(0.998)VS(0.002)VDSGEQR 81.619 0.006136600000000001 3940100.0 15642.0 11153.0 28419.0 23252.0 25460.0 26069.0 27747.0 29201.0 25598.0 24011.0 True False 18289.88165641759 12260.196132390814 29096.616739657675 21949.265824001108 20471.29576613925 24701.895748148327 25118.603289116283 28434.50469101698 25972.32232334183 28364.00422902857 0.6448272080603901 0.4322448986184878 1.0258289522421988 0.773842284282893 0.7217350413870096 0.8708888755159494 0.8855802969952018 1.0024855609743655 0.915678975141351 1.0 14.791773595962328 -4.029333780534967 0.30773481692102944 0.9867875919314997 1.472866401618918e-12 0.4853627537167927 0.1276059399371878 10.606531643144162 0.5703183172739466 0.13731707725274045 4.2678521090466495 9.346870367473954e-05 4.029333780534967 -0.9867875919300269 DRS(ph)VSVDSGEQR ddPTM_PC-9_Lapatinib_30min_R1 1 DRSVSVDSGEQR 12 1 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 DRS(0.991)VS(0.009)VDSGEQR 71.692 0.026568 0.0 9720.1 11879.0 10570.0 9146.3 12738.0 13901.0 10659.0 9566.1 11753.0 12925.0 True False 9581.489591551976 11851.494905343592 9700.975401379928 9818.94941316237 11988.775883871554 13306.486634813715 11210.87086511245 10010.575928764987 10429.253375423266 15159.069028520062 0.632063194218952 0.7818088883325457 0.6399453279834433 0.6477277327973859 0.7908649179785406 0.8777904902853253 0.73954877070752 0.6603687805584386 0.6879877224519404 1.0 13.887893534827652 -6.268643295812012 24.245965166767522 0.7773695086767705 0.6804564028774872 0.24297684140226028 0.09912924054946425 672.3613851277079 2262937.90643115 0.03087606089497928 0.0357708713382052 5.387120675679333e-07 6.268643295812012 -0.09691310579928325 DRSS(ph)FYVNGLTLGGQK ddPTM_PC-9_AZD4547_30min_R2 2 DRSSFYVNGLTLGGQK 16 1 P07737;K7EJ44;I3L3D5 P07737 PFN1 Profilin-1 1 DRS(0.358)S(0.614)FY(0.029)VNGLTLGGQK;DRS(0.286)S(0.494)FY(0.22)VNGLTLGGQK 98.804 0.0036317 0.0 77240.0 71195.0 67708.0 85210.0 87084.0 91745.0 63309.0 80048.0 55211.0 66568.0 True False 101800.71330819449 94207.39145589361 66810.1476803787 65566.15098137659 74993.88977925826 86008.1706466771 68943.37835421602 67678.42092004637 58129.34074450958 64237.47458172221 1.584755844949738 1.4665488030050746 1.0400494122069441 1.0206838205939128 1.1674476661415427 1.3389095883160609 1.0732579199779564 1.053566027629972 0.9049132320816577 1.0 15.97112755571659 -5.1755569262483485 4.142188665770485 1.0872964210424028 1.5559781764017058 0.7295022942600085 0.11026988224613786 0.12446674997286117 3.86570663026514 0.03099064633291829 0.09169243310306502 6.674874026292903e-06 5.1755569262483485 0.468681755359303 DRSS(ph)FYVNGLTLGGQK ddPTM_PC-9_Lapatinib_30min_R1 1 DRSSFYVNGLTLGGQK 16 1 P07737;K7EJ44;I3L3D5 P07737 PFN1 Profilin-1 1 DRS(0.354)S(0.646)FYVNGLTLGGQK 129.98 2.9645e-05 0.0 42458.0 32577.0 36965.0 24284.0 33840.0 35818.0 38946.0 40583.0 36076.0 29557.0 True False 41852.54113415641 32501.569958024913 33925.88038902639 26069.926369049233 31849.59773199978 34286.147635836074 40962.433315758455 42468.6343355254 32012.7409828784 34665.88806777312 1.2073119561320083 0.9375663446002916 0.9786531452100696 0.7520339971698271 0.918759031060523 0.9890457030497923 1.1816351923734176 1.2250842745611368 0.9234651920727455 1.0 15.081229099388457 -7.072778893276744 6.045100308262368 1.1005906836427657 0.9477669560468716 0.15987567041482187 0.13083768562353137 0.3631590943170328 23.560989986726735 0.051295289903889964 0.039891721522817884 8.457093005948819e-08 7.072778893276744 -0.15282372759589413 DRSVSVDS(ph)GEQR ddPTM_PC-9_Lapatinib_30min_R1 1 DRSVSVDSGEQR 12 1 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 DRS(0.007)VS(0.073)VDS(0.92)GEQR 127.78 0.0010821 3484300.0 8651.7 5558.4 7199.8 6583.1 11321.0 14349.0 16401.0 12819.0 15652.0 12252.0 True False 8528.32517147253 5545.529866307077 6607.860236031708 7067.243134577834 10655.121037942372 13735.326719152721 17250.16352929067 13414.617538060278 13889.106937133078 14369.741875236194 0.5934918835368678 0.3859171524760549 0.45984543726698607 0.49181420208786253 0.7414970380438539 0.9558506226770309 1.2004504798390563 0.9335322551046021 0.9665522914554638 1.0 13.81074652633695 -6.537831158780651 2.1139560546513034 1.0256322348839955 0.4693602798325566 0.9018202934811321 0.08237173913951618 0.091267088979322 0.8222764041718404 0.030986643983065474 0.03310910703189855 2.8984702106464514e-07 6.537831158780651 -0.5562719550514388 DRT(ph)PPHLLYSDR ddPTM_PC-9_AZD4547_30min_R2 3 DRTPPHLLYSDR 12 1 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 DRT(1)PPHLLYSDR;DRT(1)PPHLLYSDR;DRT(1)PPHLLYSDR 71.279 0.020022 17013000.0 16492.8 15603.3 24235.5 25954.4 24239.6 26015.2 24613.3 33468.3 24485.4 23761.7 True False 21737.16732844889 20646.76158583809 23914.121434805624 19971.014071482718 20874.349945952315 24388.465431439738 26803.836017719852 28296.54326002387 25779.648256065186 22929.81011549859 0.9479872366564617 0.900433168955143 1.0429271465550307 0.870962906839949 0.9103586048382948 1.0636139291426239 1.168951503859282 1.2340504835187374 1.12428529177572 1.0 14.484936787387353 -6.950734906044998 3.518543940871956 1.1492704760036774 0.9355694505975375 0.6394749817951825 0.06976933478576446 0.1384094490695947 3.546053809342258 0.026047306699257637 0.022030783682666245 1.1201213984941918e-07 6.950734906044998 -0.2137010254061399 DRT(ph)PPHLLYSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DRTPPHLLYSDR 12 1 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 DRT(1)PPHLLYSDR;DRT(1)PPHLLYSDR;DRT(1)PPHLLYSDR 76.156 0.013668000000000001 16997400.0 32224.4 35235.0 31312.5 33451.1 35313.1 26794.2 32003.4 23673.800000000003 29139.7 24357.0 True False 37679.35445908855 38732.89793999734 32059.108753317527 31576.943316929446 28393.751552209404 25389.06498350669 28971.80626744885 23052.387834464484 29565.81298560369 28772.73129009408 1.3095508410096908 1.3461668810472769 1.114218474085388 1.0974607519377488 0.9868285101590215 0.8824002395715445 1.0069188766039499 0.8011887228238562 1.0275636569748472 1.0 14.812414556888147 -5.611237500357676 1.0398012799769356 0.9334727130563328 1.3696665254232625 0.8077973677690863 0.07066172523792982 0.2580751591362659 0.492712546988529 0.024734008027336215 0.09267466977686407 2.44772430154905e-06 5.611237500357676 0.43619381236692967 DRT(ph)PPHLLYSDRDR ddPTM_PC-9_AZD4547_30min_R2 3 DRTPPHLLYSDRDR 14 2 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 DRT(1)PPHLLYSDRDR;DRT(1)PPHLLYSDRDR;DRT(1)PPHLLYSDRDR 88.021 0.0027761 44342500.0 29410.3 28822.4 38573.0 52361.0 56269.0 45303.0 36302.0 45471.0 39753.7 36121.5 True False 38762.16362775758 38138.677147248345 38061.49681684955 40289.98041938575 48457.0206236403 42470.19624836688 39532.80767370756 38444.50176963112 41854.999423212925 34856.89727952891 1.1120371189928655 1.0941500857463522 1.0919358803401777 1.1558682373903553 1.3901702218372318 1.2184158534761265 1.1341459154175713 1.1029238047589844 1.2007666398866181 1.0 15.089156535970742 -3.8457178515515973 15.171996306105447 1.1580236467964842 1.150524839296948 0.0 0.09925253507584723 26882956.50919514 0.0 0.024551807605731578 0.0 0.00014265340701639272 3.8457178515515973 -0.007498807499536131 DRT(ph)PPHLLYSDRDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DRTPPHLLYSDRDR 14 2 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 DRT(1)PPHLLYSDRDR;DRT(1)PPHLLYSDRDR 88.021 0.0027761 13702700.0 29980.0 28232.0 34447.0 52681.0 50083.0 48826.0 42169.0 39316.0 43313.0 43405.0 True False 35055.02186800915 31034.686381211992 35268.34712097499 49729.454364106416 40269.59567382373 46265.478606739416 38174.44704287828 38283.99665874535 43946.37068485444 51273.98290620907 0.6836804921539288 0.6052716138315406 0.6878409891716084 0.9698769540699047 0.7853806821967646 0.902318797651603 0.7445188549660243 0.746655408626532 0.8570890770323347 1.0 15.645939348590574 -5.593495492746659 7.917373530764576 0.8412409521978349 0.6449446271710968 0.5399461897857767 0.08382167600886302 0.1830849111259763 17.828224560540015 0.02222514057427584 0.0386501533283532 2.5497905502408233e-06 5.593495492746659 -0.1962963250267381 DRT(ph)PPHLLYSDRDR ddPTM_PC-9_Lapatinib_30min_R1 2 DRTPPHLLYSDRDR 14 2 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 DRT(1)PPHLLYSDRDR;DRT(1)PPHLLYSDRDR 85.554 0.0032330999999999996 29067000.0 28788.0 29164.0 38123.2 28032.0 33021.0 27942.9 24441.7 34070.4 32879.8 25910.8 True False 28377.477840927368 29096.47254983081 34988.85765580769 30093.566792010723 31078.769701783844 26747.84730508137 25707.171631843423 35653.43516411019 29176.530684356512 30389.44725602922 0.9337938134197988 0.9574531680255591 1.1513489324445003 0.9902637102437 1.022682954380418 0.8801689310020154 0.8459242912601235 1.1732176259650988 0.9600875737734234 1.0 14.891282813927996 -7.764092730031108 24.999824264235237 1.0499893878887157 0.9748778984956472 0.11816774599916158 0.09328501072276106 165.9884315576452 1563873.9188653182 0.05022666210833162 0.025854854144684636 1.721500962943417e-08 7.764092730031108 -0.07511148939306844 DRT(ph)PPLLYR ddPTM_PC-9_AZD4547_30min_R2 1 DRTPPLLYR 9 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 DRT(0.999)PPLLY(0.001)R 69.26100000000001 0.029439 128500000.0 5563.6 4814.7 11018.0 10757.0 8806.5 8335.4 6776.6 9182.8 8141.0 5891.1 True False 7332.709069931016 6370.957618409868 10871.89412096669 8277.139843993287 7583.869486255096 7814.186120315148 7379.704271986294 7763.809259751682 8571.316639819095 5684.854382111285 1.2898675281824434 1.1206896764950682 1.912431416920305 1.4559985687653196 1.3340481525999157 1.374562230635898 1.2981342662370117 1.3657006385567783 1.5077460324737135 1.0 12.4729076795322 -6.261891632678605 17.271891163043943 1.3339482806518481 1.4550062471454221 0.07224470359349078 0.22224864780037787 1.8796465840668395 71553.75109089118 0.06868035927690504 0.08283519229320162 5.471524740712885e-07 6.261891632678605 0.12105796649357403 DRTCTPTPVERAPY(ph)KGEVAT(ph)LK ddPTM_PC-9_AZD4547_30min_R2 1 DRTCTPTPVERAPYKGEVATLK 22 3 Q14117 Q14117 DPYS Dihydropyrimidinase 2 DRT(0.001)CT(0.004)PT(0.003)PVERAPY(0.994)KGEVAT(0.998)LK 46.678000000000004 0.031768 4668700.0 3418.5 3490.7 12386.0 15062.0 14105.0 7717.3 3574.8 17143.0 6341.3 7845.4 True False 4505.511890782796 4619.00051064102 12221.753547131362 11589.688605580262 12146.764220022495 7234.736011026241 3892.9502746947755 14493.943256950282 6676.4881719794685 7570.734933953907 0.5951221288406328 0.6101125651520719 1.6143417585944202 1.5308538347580753 1.6044366004079214 0.9556187178842112 0.5142103519217567 1.9144697817838732 0.8818811159318443 1.0 12.886217642218545 -5.239598288577231 23.28247215237424 1.2702508935072747 0.6026167349415532 0.2947898822248689 0.40094641312286794 415.9922827489569 443440.20187105524 0.10340353329959608 0.2728550425557454 5.759724509828524e-06 5.239598288577231 -0.6676341585657215 DRVHHEPQLSDK ddPTM_PC-9_AZD4547_30min_R2 2 DRVHHEPQLSDK 12 1 O43852;O43852-3;O43852-5;O43852-2;O43852-4;O43852-9;O43852-13;O43852-14;O43852-11;O43852-10;O43852-6;O43852-12;O43852-7;O43852-8 O43852 CALU Calumenin 0 ; 62.088 0.023937 4314900.0 64586.0 66735.0 98414.0 97150.0 85406.0 93765.0 84384.0 92837.0 87876.0 89311.0 False True 85123.00452774546 88305.78367594717 97108.96605743484 74753.56845253776 73548.85111486999 87901.85972734954 91894.0125265314 78491.17483203002 92520.94595759042 86184.24907415267 0.9876863283278814 1.0246162683388833 1.1267600182242417 0.8673692612697711 0.8533908678787556 1.019929519275837 1.0662506608077083 0.9107368884132929 1.0735249996549332 1.0 16.39513660780851 -10.413915301035624 18.20077196813692 0.9999999999998211 0.9899955270787612 0.00011174398870905655 0.08577673463404357 0.0 0.0 0.08606532469893748 0.020873907319811754 3.855535435201234e-11 10.413915301035624 -0.010004472921059993 DRVHHEPQLSDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DRVHHEPQLSDK 12 1 O43852;O43852-3;O43852-5;O43852-2;O43852-4;O43852-9;O43852-13;O43852-14;O43852-11;O43852-10;O43852-6;O43852-12;O43852-7;O43852-8 O43852 CALU Calumenin 0 58.754 0.030168 1608900.0 18634.0 14832.0 18535.0 19156.0 19916.0 19563.0 19497.0 17994.0 22684.0 15620.0 False True 21788.36816172392 16304.422938726853 18976.944694378948 18082.751424589926 16013.60276820225 18537.08184130675 17650.10301394385 17521.676566218946 23015.710586088215 18451.782352148028 1.1808272906052064 0.8836231984293271 1.0284613340981548 0.9800002557739285 0.8678621101520883 1.004622831959038 0.956552742553304 0.9495926318564665 1.2473434894710258 1.0 14.171472559868139 -8.233791119776653 24.849598342937686 1.1236718235451773 0.9758583128000833 0.24788639276626157 0.09871495096358227 728.9241158795251 655141.8834004167 0.06174146512005822 0.023323539780869627 5.837257881439663e-09 8.233791119776653 -0.14781351074509397 DRYDSDR ddPTM_PC-9_AZD4547_30min_R2 1 DRYDSDR 7 1 E7EX17;P23588-2;P23588;F8VX11 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 81.191 0.031505 5389400.0 23108.0 22978.0 17540.0 10809.0 13416.0 15436.0 9365.1 13998.0 30163.0 27975.0 False True 30455.86332374109 30405.18914071946 17307.408139567597 8317.152047385285 11553.419977016796 14470.784479831165 10198.575757397346 11834.930742039893 31757.354601015057 26995.603764927295 1.1281786319337435 1.1263015046998839 0.641119505615703 0.30809283318163583 0.42797412784769817 0.5360422610229454 0.3777865405865581 0.4384021504055354 1.176389862495842 1.0 14.720436863012884 -5.2922944100074805 4.505610767319884 0.5603350202849046 1.1353727179805286 0.3652373742558752 0.26539759481806885 0.1781922195130361 8.953055428130593 0.06902694058444069 0.16322146109635 5.101590438214797e-06 5.2922944100074805 0.5750376976956241 DRYNS(ph)DNDR ddPTM_PC-9_Lapatinib_30min_R1 2 DRYNSDNDR 9 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 DRY(0.14)NS(0.86)DNDR;DRYNS(1)DNDR 110.38 0.011128 3345500.0 29645.7 28886.0 24514.9 22674.3 30920.0 26321.0 27038.3 39952.0 35097.0 31252.0 True False 29222.946881644468 28819.11624175056 22499.37955225058 24341.843661247436 29101.346391058916 25195.312187247786 28438.21087458202 41808.31577194665 31144.006272205446 36653.866559327565 0.7972677816771256 0.7862503726613463 0.6138337279051671 0.6641002968090142 0.7939502465300838 0.6873848396448685 0.7758584166980645 1.1406249789302896 0.8496786068066267 1.0 15.16167777359027 -7.618988556832363 6.669024616741983 0.9945691888292099 0.7229307882305024 0.6704510328264122 0.085904744087608 0.12300923970079032 7.244934161559659 0.03989991971667617 0.02279572830843375 2.40442615307773e-08 7.618988556832363 -0.2716384005987075 DS(ph)DGVDGFEAEGK ddPTM_PC-9_Lapatinib_30min_R1 1 DSDGVDGFEAEGK 13 0 Q96KR1 Q96KR1 ZFR Zinc finger RNA-binding protein 1 DS(1)DGVDGFEAEGK 133.04 4.8778999999999995e-05 1463600.0 4253.9 5314.8 5694.3 5962.3 9769.8 6135.9 9892.9 10561.0 8246.5 8255.3 True False 4193.238605930281 5302.4939071403405 5226.136634633651 6400.78743164974 9195.15957216583 5873.481860481505 10405.105955668536 11051.702614826 7317.692330505233 9682.217605504191 0.4330865899508899 0.547652833595266 0.5397664923026181 0.6610869216584216 0.9496956117716797 0.6066256822344626 1.0746614442701012 1.1414433206441545 0.7557868071819868 1.0 13.24112180344812 -6.118006356064044 0.6815679064789798 0.9923559733176444 0.4188692374005178 0.6434462203297623 0.1426459102393933 0.5661588854494547 0.5356816183301985 0.08683753261643488 0.19420728911709836 7.620678567924078e-07 6.118006356064044 -0.5734867359171265 DS(ph)ETDMVRQIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSETDMVRQIR 11 1 E9PMB6;E9PJ36 E9PMB6 VPS51 1 DS(1)ETDMVRQIR 105.17 0.0056268 993940.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DS(ph)FDNCSLGESSK ddPTM_PC-9_AZD4547_30min_R2 1 DSFDNCSLGESSK 13 0 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 DS(1)FDNCSLGESSK 108.66 0.0008727 5058400.0 24589.0 22531.0 24151.0 24693.0 32513.0 31393.0 28093.0 31482.0 26931.0 26810.0 True False 32407.79051702742 29813.705132280887 23830.741960016934 19000.410353046966 27999.131165231574 29429.9907473011 30593.222576647728 26617.180284390637 28354.517679273806 25871.39006032891 1.2526497587279395 1.1523812621880378 0.92112336849495 0.7344178379569222 1.0822430143854285 1.1375496515136592 1.1825117438725976 1.02882683235507 1.095979675353916 1.0 14.65906995113169 -6.495249881403032 24.993668268606335 1.0980964621250426 1.0044926566686674 0.05978410560747016 0.1365474295181956 2024.013778311964 1830968.2308263557 0.04655973675790164 0.05266725914146324 3.1970550805984945e-07 6.495249881403032 -0.09360380545637526 DS(ph)FDNCSLGESSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSFDNCSLGESSK 13 0 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 DS(1)FDNCSLGESSK 180.95 8.9625e-05 3043600.0 13917.0 21962.0 12799.0 13976.0 14795.0 14378.0 19293.0 14765.0 10197.0 16823.0 True False 16272.873226720601 24142.24221819844 13104.176700477807 13192.970030803353 11896.025956796151 13623.992368977571 17465.427370775942 14377.434394810645 10346.11183417129 19872.876729205276 0.8188483956530515 1.2148337931729272 0.6594000898329855 0.663868156109221 0.5986061363382632 0.6855571316937565 0.87885753073226 0.7234702147415577 0.5206147039077937 1.0 14.278513106820299 -5.280107519102002 24.855852267136527 0.7050528811339971 1.0168411112949554 0.3689588651689708 0.1566691126211739 630.3936935858576 839342.3993419285 0.03912800499472022 0.08167350385868628 5.246775487613017e-06 5.280107519102002 0.31178823016095825 DS(ph)FDNCSLGESSK ddPTM_PC-9_Lapatinib_30min_R1 3 DSFDNCSLGESSK 13 0 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 DS(1)FDNCSLGESSK;DS(1)FDNCSLGESSK;DS(1)FDNCSLGESSK 214.45 2.3583000000000002e-14 6304300.0 80650.0 92440.0 101223.0 92385.0 85955.0 104957.0 98905.0 97009.0 110213.0 100238.0 True False 79499.91621060121 92225.96085949657 92900.83567207928 99179.30108732566 80899.29589403205 100468.23377671685 104025.81695411833 101516.39228876567 97799.6513456585 117564.00474126042 0.676226676571352 0.7844744746699567 0.7902149631304171 0.8436196206960068 0.6881298070108999 0.8545832884634321 0.8848441083906807 0.8634989298993941 0.8318843132377116 1.0 16.843086883842794 -14.522875981868669 0.030522739622327863 2.2176795211583804 1.1236317657355544e-10 0.6640077803537202 0.05203009306684209 882.1100220763809 2.0187171834818 115.40033547077812 45.90507876363594 3.000019089032273e-15 14.522875981868669 -2.2176795210460174 DS(ph)GGKTPGDFSYAYQKPEETTR ddPTM_PC-9_Lapatinib_30min_R1 1 DSGGKTPGDFSYAYQKPEETTR 22 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DS(0.488)GGKT(0.419)PGDFS(0.064)Y(0.024)AY(0.005)QKPEETTR 47.821999999999996 0.016463 13642000.0 30986.0 34437.0 42192.0 35733.0 70493.0 49519.0 67296.0 37512.0 58871.0 70353.0 True False 30544.133957863527 34357.26324230297 38723.13662582989 38360.92402179364 66346.7403345703 47401.18780442705 70780.25759814311 39254.94446428869 52240.32804088685 82513.4223105199 0.3701717017980159 0.4163839322165971 0.4692950012436092 0.46490525962468626 0.8040720948997839 0.5744663895534935 0.8578029563696706 0.4757401082767106 0.6331130933376226 1.0 16.332341198614095 -6.148602161570422 5.514095437236323 0.6965880167326447 0.42637967398707854 0.5010935956819351 0.14245042845774786 0.20989396756224377 8.83901156660576 0.04070419859346499 0.05303349795220558 7.10228079344992e-07 6.148602161570422 -0.27020834274556615 DS(ph)GPLPTPPGVSLLGEPPKDYR ddPTM_PC-9_Lapatinib_30min_R1 1 DSGPLPTPPGVSLLGEPPKDYR 22 1 A0A087WZ13;Q8IY67-2;E9PAU2 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 DS(0.529)GPLPT(0.47)PPGVS(0.001)LLGEPPKDYR 53.059 0.009908799999999999 6335500.0 26863.0 24537.0 32072.0 21953.0 30508.0 29747.0 28268.0 33726.0 27857.0 20827.0 True False 26479.92869392915 24480.18608404877 29435.16396150019 23567.496853061184 28713.579421035756 28474.79015364388 29731.578723613733 35293.03308281621 24719.45131278535 24426.919199766908 1.084047008850049 1.0021806632202055 1.2050297346454184 0.9648165886300584 1.1754891882276237 1.16571352779992 1.2171644930113596 1.444841766339203 1.011975808763523 1.0 14.576184297371015 -6.4514787061823125 9.976765099453663 1.1957196949069602 1.0695400363627974 0.11768257653374692 0.13021641187135677 0.9785123442217446 132.88429264179848 0.039053341636798806 0.0442473573751532 3.5360735833663016e-07 6.4514787061823125 -0.1261796585441628 DS(ph)GRGDSVSDSGSDALR ddPTM_PC-9_Lapatinib_30min_R1 1 DSGRGDSVSDSGSDALR 17 1 Q53EL6;Q53EL6-2;Q5VZS7 Q53EL6 PDCD4 Programmed cell death protein 4 1 DS(0.981)GRGDS(0.011)VS(0.008)DSGSDALR 81.44800000000001 0.024582 8004900.0 1107.3 1679.6 1459.8 2087.3 3576.9 4913.8 3323.7 2075.6 4899.7 1479.0 True False 1091.5096989460492 1675.710989394317 1339.7808789909575 2240.807005028681 3366.5137744559706 4703.648228627267 3495.784923011001 2172.0399533503305 4347.844189871639 1734.643179356377 0.6292416284431727 0.9660263328715671 0.7723668446256887 1.2917970863956652 1.9407528963421075 2.711594110307176 2.0152760894076667 1.2521537450464282 2.5064775520489846 1.0 10.760423211837061 -6.058300646179967 2.799430521939629 1.9624980417229185 0.8100524716805576 0.5155526457978267 0.4856008013360326 0.21432501034622314 3.3218351074793855 0.1488802480130393 0.21331503233350566 8.743782655837938e-07 6.058300646179967 -1.152445570042361 DS(ph)GRLSPDLSVCGQPR ddPTM_PC-9_AZD4547_30min_R2 2 DSGRLSPDLSVCGQPR 16 1 Q8TF76-2;Q8TF76 Q8TF76-2 GSG2 Serine/threonine-protein kinase haspin 1 DS(0.732)GRLS(0.268)PDLS(0.001)VCGQPR;DS(0.931)GRLS(0.069)PDLSVCGQPR 61.861999999999995 0.018761 39185000.0 20590.1 19437.7 22782.0 36892.0 27768.0 28533.0 22471.2 24771.0 18845.800000000003 28887.0 True False 27137.323499314592 25720.556400059304 22479.895794505635 28387.11937571819 23912.892510569633 26748.826999418412 24471.0932675174 20943.21113095229 19841.95051353677 27875.674922518487 0.9735126978896055 0.9226882029421918 0.8064341350295329 1.018347338840092 0.8578408442857954 0.959575941166189 0.8778654987022108 0.7513077688402077 0.7118016180303521 1.0 14.766719115365627 -7.573640912946737 5.826705298493326 0.7998636436938948 0.9191858742878904 0.1934371885524624 0.09006403362390505 0.2599093542308606 19.641824188546515 0.04086259798186069 0.023412629804296474 2.6690646111039988e-08 7.573640912946737 0.1193222305939956 DS(ph)GRLSPDLSVCGQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSGRLSPDLSVCGQPR 16 1 Q8TF76-2;Q8TF76 Q8TF76-2 GSG2 Serine/threonine-protein kinase haspin 1 DS(0.983)GRLS(0.017)PDLSVCGQPR 123.76 0.00018241 3775700.0 8790.1 8382.9 10142.0 10277.0 11336.0 6524.0 10076.0 11791.0 7222.8 8294.4 True False 10278.09031761132 9215.098911343935 10383.823743749186 9701.21300848354 9114.792176156887 6181.86995515438 9121.528336077256 11481.498743597183 7328.41978580488 9798.109061565729 1.0489871313974628 0.9404976872008171 1.0597783387083324 0.9901107394831647 0.9302603307316475 0.6309247954182827 0.9309478266431588 1.1718076081266287 0.7479422549552439 1.0 13.25828763483606 -6.287235252575027 4.4464274522983835 0.8972783029357483 1.00950340432174 0.13028811396556528 0.1378202108218135 0.4743389410185736 23.416341701348568 0.04462513218419187 0.05312011799188918 5.16136707919644e-07 6.287235252575027 0.11222510138599162 DS(ph)GRLSPDLSVCGQPR ddPTM_PC-9_Lapatinib_30min_R1 2 DSGRLSPDLSVCGQPR 16 1 Q8TF76-2;Q8TF76 Q8TF76-2 GSG2 Serine/threonine-protein kinase haspin 1 DS(0.901)GRLS(0.075)PDLS(0.024)VCGQPR;DS(1)GRLSPDLSVCGQPR 181.81 9.873099999999999e-06 13785400.0 32965.0 28335.0 33769.0 29149.0 31254.0 30974.0 29804.0 27497.0 33910.0 25844.0 True False 32494.913054959394 28269.39204839722 30992.64317210963 31292.714698213487 29415.701167728173 29649.314223920574 31347.105287908005 28774.61100273369 30090.698711869583 30311.100965034606 1.0720466106606925 0.9326415454525192 1.02248490438738 1.0323846281371047 0.9704596742183887 0.9781668524057427 1.0341790396880828 0.9493093317833181 0.9927286622343653 1.0 14.88755863444137 -6.271693411080096 24.803749452288876 0.9868092966115429 1.0095571090905984 0.10290864231526364 0.038354062811045926 1796.2934098795668 4345087.557020143 0.011543576809451088 0.013213694460854497 5.349418667782062e-07 6.271693411080096 0.02274781247905544 DS(ph)HSPDLQLPTPEVIPSSGSK ddPTM_PC-9_AZD4547_30min_R2 2 DSHSPDLQLPTPEVIPSSGSK 21 0 H3BPE1;H3BQK9;H0Y6T5;H0Y4F5 H3BPE1 MACF1 1 DS(0.5)HS(0.5)PDLQLPTPEVIPSSGSK;DS(0.5)HS(0.5)PDLQLPTPEVIPSSGSK 120.27 1.1488e-06 36980000.0 160767.0 188077.0 225794.0 201781.0 206146.0 248658.0 240176.0 279462.0 228748.0 224510.0 True False 211887.561838666 248869.21220380752 222799.82402882155 155263.5079353733 177526.1862389759 233109.37595140302 261551.19871743614 236277.5692978961 240839.15228170223 216649.97323552557 0.9780179460641695 1.1487156378886583 1.0283861137919934 0.7166560217691902 0.8194147619209847 1.0759723274832074 1.20725239339447 1.0905958850086397 1.1116509671565018 1.0 17.725006532819144 -6.946187680664855 10.084395840572915 1.1144407850519635 0.9428965134081106 0.3107575052018656 0.11816321146159703 0.5721533673018535 103.40164260656681 0.046672521205188396 0.041146416131009306 1.1319111013496627e-07 6.946187680664855 -0.17154427164385289 DS(ph)HSPDLQLPTPEVIPSSGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DSHSPDLQLPTPEVIPSSGSK 21 0 H3BPE1;H3BQK9;H0Y6T5;H0Y4F5 H3BPE1 MACF1 1 DS(0.812)HS(0.188)PDLQLPTPEVIPSSGSK;DS(0.5)HS(0.5)PDLQLPTPEVIPSSGSK 101.42 9.652200000000001e-05 30457000.0 96260.0 135876.0 135423.0 116528.0 138554.0 104796.0 121109.0 104366.0 107392.0 98258.0 True False 112554.91677833778 149364.87130679973 138651.99791458718 109999.31394887343 111405.33831821127 99300.31327718565 109636.67876677071 101626.50308491767 108962.40483429651 116071.39759010011 0.9697041572276006 1.2868361578127432 1.1945406085677477 0.9476866500507738 0.9598000940044956 0.8555106196606622 0.9445624076479784 0.8755516448919327 0.9387532768330349 1.0 16.824652980329134 -5.798716791738443 6.402085870114118 0.9238827367155494 1.1641881669629235 0.5908872420253573 0.08302924154968079 0.10885346130670805 12.219028379573382 0.02256947922899672 0.03449861655152262 1.5895829954365265e-06 5.798716791738443 0.24030543024737405 DS(ph)HSPDLQLPTPEVIPSSGSK ddPTM_PC-9_Lapatinib_30min_R1 3 DSHSPDLQLPTPEVIPSSGSK 21 0 H3BPE1;H3BQK9;H0Y6T5;H0Y4F5 H3BPE1 MACF1 1 DS(0.5)HS(0.5)PDLQLPTPEVIPSSGSK;DS(0.5)HS(0.5)PDLQLPTPEVIPSSGSK;DS(0.561)HS(0.439)PDLQLPTPEVIPSSGSK 112.55 6.0784e-05 31345000.0 66592.0 109987.0 99103.0 83436.0 102021.0 99798.0 101611.0 87223.0 94658.0 78012.0 True False 65642.38586852276 109732.33185908096 90955.13388864261 89572.1617743367 96020.32536100317 95529.87218050046 106871.92039355847 91275.69900321637 83996.61924707016 91496.27025554395 0.7174323683925833 1.199309344005004 0.9940857002652679 0.9789706348047486 1.0494452406947714 1.0440848781452063 1.1680467421794483 0.9975892869544132 0.918033259852804 1.0 16.481425314273977 -4.7426353643308055 24.99002126247114 1.0400286686738731 0.7174313089030399 0.584841228718632 0.08123376049634945 924.4269324449273 1228473.9895682905 0.020204493001587404 0.7057442486958166 1.8086920749711368e-05 4.7426353643308055 -0.32259735977083326 DS(ph)KPS(ph)S(ph)T(ph)PRS(ph)KGQESFK ddPTM_PC-9_AZD4547_30min_R2 1 DSKPSSTPRSKGQESFK 17 3 P06748;P06748-3 P06748 NPM1 Nucleophosmin 5 DS(0.999)KPS(0.999)S(0.995)T(0.996)PRS(0.947)KGQES(0.063)FK 48.229 0.031672000000000006 2525700.0 3982.4 6452.3 7513.8 14993.0 12277.0 9496.0 8770.5 12032.0 8080.7 12078.0 True False 5248.720360934158 8537.87979339647 7414.162102570295 11536.595489540894 10572.550466445678 8902.213618844042 9551.057509290184 10172.73086785427 8507.829304923984 11655.152896257077 0.4503347495870025 0.7325412089736133 0.6361273994913675 0.9898278977743606 0.9071138371630402 0.7638006723792434 0.8194708035411015 0.8728097313181649 0.7299629083078076 1.0 13.50868030990426 -4.441240328553155 0.9951437120149492 0.8518192990996747 1.1355083120758205e-06 0.5934145078124329 0.10124520546843865 2.453900877303477 1.239553234500723 0.03254699634553806 2.6262743571905265 3.620425969471704e-05 4.441240328553155 -0.8518181635913626 DS(ph)LGAYASQDANEQGQDLGKR ddPTM_PC-9_AZD4547_30min_R2 3 DSLGAYASQDANEQGQDLGKR 21 1 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 DS(0.997)LGAY(0.002)ASQDANEQGQDLGKR;DS(1)LGAYASQDANEQGQDLGKR;DS(1)LGAYASQDANEQGQDLGKR 184.57 2.5850999999999997e-15 138289000.0 144730.0 166991.0 164511.0 167903.0 202425.0 237103.0 201656.0 235660.0 206420.0 198253.0 True False 190751.12942898815 220967.57506301175 162329.47665042206 129195.55742549087 174321.78285984084 222276.91192805165 219602.99334056422 199244.16192807 217330.93978521784 191312.2228135165 0.9970671325842296 1.155010233080623 0.8485055176461691 0.6753126147691333 0.9111899924437276 1.1618542122356619 1.1478774858761869 1.0414607022902307 1.1360013311698507 1.0 17.545569523913457 -6.750591904443327 24.58517883325956 1.1031824584850147 0.9133379922637633 0.3542219285790792 0.12134796945863832 215.16861402801652 487666.20401795214 0.04475347344800971 0.044312423868137434 1.7758574254787275e-07 6.750591904443327 -0.1898444662212514 DS(ph)LGAYASQDANEQGQDLGKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DSLGAYASQDANEQGQDLGKR 21 1 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 DS(1)LGAYASQDANEQGQDLGKR;DS(1)LGAYASQDANEQGQDLGKR 145.14 1.4358e-06 40280000.0 74749.0 89508.0 86680.0 82089.0 83993.0 85795.0 101944.0 61399.0 73483.0 69920.0 True False 87402.52933995395 98393.76270223592 88746.77993573068 77489.81946612896 67535.17459879565 81295.75916653448 92287.12630935492 59787.34130761791 74557.54985882202 82595.94251358455 1.0581939824172217 1.1912662984147568 1.0744690021684116 0.9381794929379759 0.8176572909460794 0.9842585082573974 1.1173324439536054 0.7238532485755543 0.9026781169857048 1.0 16.33378329122676 -5.703710373509574 3.6436845323053113 0.9193957730526731 1.1258387612598073 0.39579919182038925 0.10389097234963583 0.22536084711946303 6.030054348962943 0.030065100368049866 0.05338197143946816 1.978288500400492e-06 5.703710373509574 0.20644298820713425 DS(ph)LGAYASQDANEQGQDLGKR ddPTM_PC-9_Lapatinib_30min_R1 3 DSLGAYASQDANEQGQDLGKR 21 1 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 DS(1)LGAYASQDANEQGQDLGKR;DS(0.999)LGAY(0.001)ASQDANEQGQDLGKR;DS(1)LGAYASQDANEQGQDLGKR 134.34 7.6715e-07 169290400.0 93607.0 111814.0 104840.0 90619.0 129955.0 136089.0 114251.0 119321.0 125144.0 93885.0 True False 92272.14701457869 111555.10155283171 96220.45989410342 97283.42355612224 122311.30240136034 130268.79070895365 120166.35774556374 124865.08926272669 111048.96489525818 110112.89715610091 0.8379776520071905 1.0130975065953107 0.8738346041126958 0.8834880024835688 1.11078089452107 1.1830475273416778 1.0913013902014639 1.1339733354369237 1.008500981840758 1.0 16.74862393129039 -6.263858626543946 24.96277682374131 1.0995567379982478 0.9080089528921662 0.649218861618136 0.06653510021213878 126.69301038534014 1307267.552893156 0.019819885623314402 0.02355521840290889 5.446799306011211e-07 6.263858626543946 -0.19154778510608161 DS(ph)LGTYSSR ddPTM_PC-9_AZD4547_30min_R2 3 DSLGTYSSR 9 0 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 DS(0.993)LGT(0.007)YSSR;DS(0.99)LGT(0.009)YS(0.001)SR;DS(1)LGTYSSR 130.01 0.0012797000000000002 129114000.0 152186.0 174865.0 217636.0 201920.0 227011.0 227303.0 205554.0 292953.0 226606.0 189774.0 True False 200577.98233455312 231386.6915785491 214750.00443916384 155370.463632902 195494.44114509257 213089.70747726524 223847.90778913753 247683.84524023536 238583.93053468218 183130.07002271008 1.0952760642186141 1.2635100917607616 1.1726638034514625 0.8484159024983413 1.0675168808751572 1.1635975864086103 1.2223438114853449 1.3525023236736595 1.3028113324321628 1.0 17.482509176062443 -7.096260042555811 2.8793566403545365 1.2494963764562563 1.091660830163838 0.16424449999242507 0.13134350574378376 0.4420302762617882 7.095957456640605 0.05748913993907643 0.04362851479301208 8.011981862058259e-08 7.096260042555811 -0.15783554629241836 DS(ph)LGTYSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DSLGTYSSR 9 0 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 DS(1)LGTYSSR;DS(0.999)LGT(0.001)YSSR;DS(1)LGTYSSR;DS(1)LGTYSSR 146.71 0.00042235 115293000.0 156458.0 220152.0 336836.0 222860.0 305596.0 200891.0 266460.0 179952.0 184228.0 187590.0 True False 182943.24921364183 242007.23562611834 344867.4476976432 210373.876721869 245716.65753924142 190355.9223116061 241218.97979665975 175228.45067490416 186921.98597486585 221598.58203837756 0.8255614613181902 1.0920974015267224 1.5562710037463927 0.9493466735515275 1.108836777198723 0.8590123662372501 1.0885402676217677 0.7907471657221941 0.8435161644784069 1.0 17.757589124358454 -6.567944469875396 1.7380223592034152 0.9098410830316416 1.1409781987272107 0.17841092697144745 0.19386534975923064 0.5945785787392157 3.6612302360298234 0.07797297596874475 0.08232898257090952 2.704304122001068e-07 6.567944469875396 0.23113711569556916 DS(ph)LGTYSSR ddPTM_PC-9_Lapatinib_30min_R1 4 DSLGTYSSR 9 0 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 DS(0.998)LGT(0.002)YSSR;DS(0.976)LGT(0.023)YSSR;DS(0.916)LGT(0.083)YSSR;DS(0.999)LGT(0.001)YSSR 152.69 8.954899999999999e-05 169065000.0 173992.0 234126.0 284160.0 208665.0 290767.0 345168.0 285326.0 274465.0 311394.0 232485.0 True False 171510.8421737747 233583.89563165838 260797.4616893211 224010.92018603472 273664.65672991646 330405.9692659073 300098.7841691599 287217.6458837436 276321.52859580977 272669.72248320933 0.6290058192446949 0.8566550532431858 0.9564591892133556 0.8215467348041513 1.0036488622119326 1.2117442532925646 1.1005944533780776 1.053353644357892 1.013392781858372 1.0 18.056794985293443 -6.370220944923455 3.6318826853297193 1.0829666584108886 0.8277885440261015 0.6312710144606812 0.09356411581157927 0.1698531705224426 4.093975719650697 0.03135103579550285 0.03606014425743057 4.263625540175826e-07 6.370220944923455 -0.2551781143847871 DS(ph)LSPVLHPSDLILTR ddPTM_PC-9_AZD4547_30min_R2 1 DSLSPVLHPSDLILTR 16 0 Q9HCN4-3;Q9HCN4-2;Q9HCN4-4;Q9HCN4;Q9HCN4-5 Q9HCN4-3 GPN1 GPN-loop GTPase 1 1 DS(0.823)LS(0.177)PVLHPSDLILTR 104.84 0.00067935 17712000.0 3187.1 2381.9 18688.0 37373.0 21399.0 17917.0 8158.5 26165.0 11911.0 18817.0 True False 4200.531504201801 3151.80259440681 18440.18490947772 28757.232257094096 18428.118223627185 16796.647157627303 8884.590694891276 22121.800461885556 12540.591143211563 18158.222557449033 0.231329442676019 0.17357440049185038 1.0155280810738283 1.5837030395520204 1.0148635509518762 0.9250160418777789 0.48928746559759273 1.2182800597303256 0.6906287828302361 1.0 14.148335368904322 -5.262095914141422 24.647569453622673 1.0015382784160027 0.20245184071941588 0.5697920213368488 0.27438249977143303 33.01729462490466 1239610.4441640228 0.07462585609173313 0.17193789692072983 5.46895167499592e-06 5.262095914141422 -0.7990864376965868 DS(ph)LSPVLHPSDLILTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSLSPVLHPSDLILTR 16 0 Q9HCN4-3;Q9HCN4-2;Q9HCN4-4;Q9HCN4;Q9HCN4-5 Q9HCN4-3 GPN1 GPN-loop GTPase 1 1 DS(0.537)LS(0.463)PVLHPSDLILTR 65.47 0.016097 8023800.0 2158.3 2697.3 9365.4 6493.4 11549.0 10659.0 8510.5 6823.4 8805.5 4175.3 True False 2523.6575616318937 2965.070118165313 9588.70665447729 6129.595849886842 9286.056355190187 10100.02327590291 7704.3238293157465 6644.292979989902 8934.263779130655 4932.248838343386 0.5116646877207284 0.601159879670873 1.9440841224259657 1.242758841004789 1.8827225996791217 2.0477521728800783 1.5620306439979676 1.3471122803734183 1.8113976143449086 1.0 12.268029872072725 -5.248885813916109 24.202630373958943 1.6284268244406217 0.5564118968346458 0.6357595705547743 0.3169903915717174 290.5417930047722 560145.4721136183 0.07807655182044042 0.2032189885947854 5.637858687111924e-06 5.248885813916109 -1.0720149276059758 DS(ph)PGIPPSAGAHQLFR ddPTM_PC-9_AZD4547_30min_R2 2 DSPGIPPSAGAHQLFR 16 0 E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2;Q5SVM6 E9PGT3 RPS6KA1 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 DS(0.999)PGIPPS(0.001)AGAHQLFR;DS(1)PGIPPSAGAHQLFR 68.525 0.013082 13028700.0 33648.0 26978.0 60500.0 68883.0 70081.0 78929.0 52253.0 95324.0 65754.0 60940.0 True False 44347.36407812187 35698.11091645615 59697.73047000224 53003.08858174115 60351.46283611459 73993.55715266861 56903.415772526074 80593.8661276049 69229.6222005485 58806.50914869242 0.7541233907625674 0.6070435302696403 1.015155147520428 0.9013132959095173 1.0262718142904173 1.2582545405913432 0.9676380488534974 1.3704922685314151 1.1772442065129425 1.0 15.843688231835614 -5.667888808533932 0.7788646002669996 1.175032282274592 0.6190773329277292 0.6065104120900036 0.13473553896649895 0.6324700032707932 0.635867343203611 0.06076002238257458 0.24957399502236954 2.148380448869291e-06 5.667888808533932 -0.5559549493468628 DS(ph)PGIPPSAGAHQLFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DSPGIPPSAGAHQLFR 16 0 E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2;Q5SVM6 E9PGT3 RPS6KA1 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 DS(1)PGIPPSAGAHQLFR;DS(1)PGIPPSAGAHQLFR 87.676 0.0082204 0.0 34351.0 52575.0 67769.0 60472.0 83566.0 58848.0 86402.0 51332.0 60460.0 45914.0 True False 40165.94583682399 57794.29854392966 69384.86997536372 57083.94989286925 67191.84218355032 55761.90728401672 78217.37706369058 49984.58939074975 61344.11312091749 54237.844744975984 0.7405520264620126 1.0655714439922155 1.2792704116767248 1.052474525145229 1.2388368767137314 1.0280996146916754 1.442118089895816 0.9215814091761046 1.1310204785856606 1.0 15.72701223063593 -4.788217587179673 3.783498743400598 1.143224787540266 0.7025963673137592 0.40018417979087584 0.144489573847785 0.22993477465742473 5.841873967740718 0.03407420786848086 0.2797781316682651 1.6284799386064103e-05 4.788217587179673 -0.4406284202265067 DS(ph)PGIPPSAGAHQLFR ddPTM_PC-9_Lapatinib_30min_R1 2 DSPGIPPSAGAHQLFR 16 0 E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2;Q5SVM6 E9PGT3 RPS6KA1 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 DS(1)PGIPPSAGAHQLFR;DS(1)PGIPPSAGAHQLFR 116.04 9.413399999999999e-05 10314600.0 32468.0 32283.0 63370.0 39872.0 68227.0 80298.0 68031.0 78338.0 86464.0 56742.0 True False 32005.000366098033 32208.250696961608 58159.96321527394 42804.31988909288 64214.02199944297 76863.8417237804 71553.31230176042 81977.8694669294 76725.5138137155 66549.77909603764 0.4809182059028593 0.4839723156778935 0.8739317245718217 0.6431925164968946 0.9649021059375126 1.1549826726375543 1.0751848206513535 1.2318278224278936 1.1529041096138473 1.0 16.02214625684244 -5.931418443750442 0.7536130011169675 1.1603416975979408 0.4346320229898273 0.8276685446007194 0.10974976792230738 0.32883669395627524 0.3574236687931006 0.05647900736070935 0.15625699598827697 1.1710664964894378e-06 5.931418443750442 -0.7257096746081135 down DS(ph)PGIPPSANAHQLFR ddPTM_PC-9_AZD4547_30min_R2 3 DSPGIPPSANAHQLFR 16 0 B4DG22;B1AXG1;B7ZB17;P51812 B4DG22 RPS6KA3 Ribosomal protein S6 kinase alpha-3 1 DS(1)PGIPPSANAHQLFR;DS(1)PGIPPSANAHQLFR;DS(1)PGIPPSANAHQLFR 118.51 7.0557e-05 12523700.0 50348.0 54014.0 73952.0 92299.0 85176.0 123081.0 82962.0 125549.0 109512.0 107656.0 True False 66357.61669654299 71472.96919866046 72971.34816062162 71020.89155533485 73350.78264478088 115384.72561298906 90345.45728131023 106148.28687900909 115300.58074682097 103886.99620793633 0.6387480543159036 0.6879876385645306 0.7024108004293905 0.6836360097772207 0.706063177512272 1.110675347490453 0.869651261265444 1.021766830822085 1.1098653821508095 1.0 16.6646555542764 -6.747166767004887 22.72427701908905 1.0142058462031474 0.6850313999506656 0.8707253214076411 0.06519918035041425 27.171274040091028 43260.61702531659 0.021447914005075737 0.021319637328233828 1.7899184019450195e-07 6.747166767004887 -0.3291744462524817 DS(ph)PGIPPSANAHQLFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DSPGIPPSANAHQLFR 16 0 B4DG22;B1AXG1;B7ZB17;P51812 B4DG22 RPS6KA3 Ribosomal protein S6 kinase alpha-3 1 DS(1)PGIPPSANAHQLFR;DS(1)PGIPPSANAHQLFR 107.63 0.0005021 12560600.0 27162.0 36694.0 49031.0 50275.0 55813.0 43679.0 48493.0 33507.0 45886.0 36239.0 True False 31759.990126046217 40336.73781780224 50200.08499110298 47458.25474374919 44876.843306972856 41388.39634751509 43899.3919810832 32627.4767536011 46556.995942216694 42808.84383223386 0.7419025435611469 0.9422524461506201 1.1726568740757188 1.1086086540840996 1.048307762826845 0.9668188309339666 1.02547483303037 0.7621667354873415 1.0875555556854488 1.0 15.38562125175733 DS(ph)PGIPPSANAHQLFR ddPTM_PC-9_Lapatinib_30min_R1 4 DSPGIPPSANAHQLFR 16 0 B4DG22;B1AXG1;B7ZB17;P51812 B4DG22 RPS6KA3 Ribosomal protein S6 kinase alpha-3 1 DS(1)PGIPPSANAHQLFR;DS(1)PGIPPSANAHQLFR;DS(1)PGIPPSANAHQLFR;DS(1)PGIPPSANAHQLFR 116.79 8.700799999999999e-05 13927100.0 80697.2 88452.0 121154.0 96229.0 152269.0 161622.0 137953.0 164483.0 168902.0 122767.0 True False 79546.44312994578 88247.19482847487 111193.18578796436 103306.00167053343 143312.83679237208 154709.80381928344 145095.53133078702 172125.48065471288 149878.4781430904 143987.11237325484 0.552455298386283 0.6128825932678854 0.7722440151429701 0.7174670008155688 0.995317111581939 1.0744697998959267 1.0076980428266304 1.1954228251242065 1.040915924159681 1.0 17.13558016285959 -6.064971338879416 0.9962327520355733 1.0892083254958371 0.5755845787360614 0.8879869767683716 0.06867314881065442 0.16779481244853953 0.34227030566373073 0.028993785881512954 0.05728041557630998 8.610505750572744e-07 6.064971338879416 -0.5136237467597757 DS(ph)PVIVR ddPTM_PC-9_Lapatinib_30min_R1 1 DSPVIVR 7 0 I3L2J0 I3L2J0 CIC 1 DS(1)PVIVR 95.35799999999999 0.014952000000000002 0.0 9565.1 12263.0 12875.0 14169.0 12750.0 11946.0 13959.0 12337.0 11463.0 10441.0 True False 9428.699919975492 12234.605776936476 11816.467198937233 15211.035526398402 12000.070067464458 11435.097427486116 14681.728718088447 12910.222058432759 10171.916229258648 12245.712938242013 0.7699592475772236 0.9990929755285337 0.9649472642818293 1.2421518945537269 0.9799405006457044 0.9338041390612355 1.1989280487082972 1.0542646331448418 0.8306512067168318 1.0 13.57998914875757 -4.588216823316282 1.9826110402725863 1.0361811816429067 0.5709273237953636 0.30296101967277345 0.11468621175568626 1.8477713514735739 4.974937909365772 0.03069642729835193 1.8776440233792775 2.580971308321177e-05 4.588216823316282 -0.46525385784754314 DS(ph)PYQSR ddPTM_PC-9_AZD4547_30min_R2 1 DSPYQSR 7 0 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 1 DS(0.975)PY(0.001)QS(0.024)R 76.1 0.031751 3382300.0 19602.0 19697.0 20415.0 17084.0 20225.0 25979.0 19246.0 24178.0 25515.0 19707.0 True False 25835.028253071345 26063.670054171416 20144.28376107597 13145.547745168858 17417.1078589121 24354.529023162337 20958.856715557704 20441.845655167926 26863.670810095115 19017.06392834396 1.3585182418493928 1.370541222997355 1.0592741254369948 0.6912501211912156 0.9158673454819065 1.280667147932503 1.1021079171069936 1.074921225074098 1.4126087450364087 1.0 14.215006903193196 -5.262123386183864 22.750628830091728 1.0598179666589524 1.3645298075261592 0.29612414292623623 0.18315759494485565 21.348295740784163 710206.6394500762 0.05109829355380734 0.11778785539322892 5.468605738017798e-06 5.262123386183864 0.3047118408672067 DS(ph)PYQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSPYQSR 7 0 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 1 DS(1)PYQSR 96.665 0.012731999999999999 3445500.0 13941.0 18973.0 13504.0 12043.0 17795.0 15118.0 15714.0 9931.7 12077.0 12044.0 True False 16300.935952698994 20856.514051811257 13825.986574205193 11368.26975393279 14308.19749247634 14325.185466282037 14225.45616049206 9671.003398505985 12253.60327756072 14227.481859748452 1.1457358451333988 1.465931516020222 0.9717802988961002 0.7990359689788271 1.00567321986586 1.0068672452016967 0.9998576206755095 0.6797410458042202 0.8612629696775709 1.0 13.796392719563475 -5.383029481470313 5.710548082270615 0.9050982189451539 1.3022575661764568 0.614158277253358 0.12438690214178626 0.13769789323365184 5.798900917274467 0.03322907994198383 0.0705887014544504 4.139715719877344e-06 5.383029481470313 0.397159347231303 DS(ph)PYQSR ddPTM_PC-9_Lapatinib_30min_R1 1 DSPYQSR 7 0 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 1 DS(0.998)PY(0.001)QS(0.001)R 76.17 0.031649000000000004 3578400.0 14687.0 29395.0 23385.0 13737.0 26877.0 20593.0 25523.0 22844.0 22798.0 20921.0 True False 14477.56068673407 29326.937683523432 21462.375568710457 14747.26480528865 25296.147702215098 19712.28539462764 26844.456055001883 23905.415636122074 20230.24916641707 24537.166974519794 0.5900257638450294 1.1952047159306327 0.8746884100759349 0.6010174206583302 1.0309318809495593 0.8033643580409071 1.094032415513904 0.9742532893445379 0.8244737131806956 1.0 14.582681066702161 -7.237985706887224 24.873237998909783 0.9710443376291662 0.8630700082342995 0.09961482367014651 0.17968675606423104 2085.158023645996 2211368.0322262025 0.06757176328519222 0.052310074214203715 5.781150735004886e-08 7.237985706887224 -0.10797432939486673 DS(ph)QDGSSYR ddPTM_PC-9_AZD4547_30min_R2 1 DSQDGSSYR 9 0 Q14847;Q14847-2;C9J9W2;Q14847-3;J3KSN1 Q14847 LASP1 LIM and SH3 domain protein 1 1 DS(0.9)QDGS(0.1)SYR 128.57 0.001326 45572000.0 81051.0 85634.0 81064.0 69415.0 71831.0 103420.0 81049.0 104980.0 98170.0 83016.0 True False 106823.53203447012 113313.51583585898 79989.03839372328 53412.44420105928 61858.50554331338 96953.13105105833 88262.20398728242 88757.75320041047 103359.06578197288 80109.63510810368 1.3334667158365838 1.414480488931805 0.9984946041232411 0.666741823614376 0.7721731032707692 1.2102555569030522 1.1017676446556932 1.107953532438846 1.2902201544482799 1.0 16.289688151355847 -5.2641800192447326 24.67996356583022 1.0107753796187688 1.3739736274493048 0.3908571071272654 0.1773255755554048 204.61897507925738 1842654.0846301562 0.05173163704935934 0.1160134242049769 5.442769980208779e-06 5.2641800192447326 0.363198247830536 DS(ph)QDGSSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSQDGSSYR 9 0 Q14847;Q14847-2;C9J9W2;Q14847-3;J3KSN1 Q14847 LASP1 LIM and SH3 domain protein 1 1 DS(1)QDGSSYR 113.95 0.0020689 46716000.0 78283.0 121880.0 84781.0 92424.0 104560.0 75707.0 68627.0 80929.0 81157.0 64402.0 True False 91534.76574027244 133979.4409231412 86802.50057373311 87245.78292265095 84072.21859024039 71736.79164544345 62126.15374354647 78804.69950136347 82343.76759104058 76077.57279404857 1.2031767363039882 1.7610898455690769 1.1409735798054212 1.1468002949941123 1.105085447689483 0.942942696655739 0.8166158758998487 1.0358466576568837 1.0823658611448526 1.0 16.215183598226254 -5.45551190730873 5.316937868801775 1.020156126425096 1.4833969435120165 0.589650680324224 0.1523276842285548 0.13823521780648282 7.474343953243934 0.040263805627133616 0.08459312022825 3.5033868272697338e-06 5.45551190730873 0.46324081708692044 DS(ph)QDGSSYR ddPTM_PC-9_Lapatinib_30min_R1 2 DSQDGSSYR 9 0 Q14847;Q14847-2;C9J9W2;Q14847-3;J3KSN1 Q14847 LASP1 LIM and SH3 domain protein 1 1 DS(1)QDGSSYR;DS(1)QDGSSYR 133.88 0.001147 162568000.0 94910.0 122399.0 110078.0 95009.0 107695.0 85646.0 105118.0 89941.0 100924.0 97617.0 True False 93556.56599563746 122115.59263567232 101027.81175336798 101996.27880073285 101360.59183651641 81983.1202305773 110560.4956936758 94119.98720576319 89556.87634316509 114489.96838352337 0.8171595059074319 1.0666051738839188 0.8824162778606132 0.8908752464588109 0.8853229087894791 0.7160725204844739 0.9656784542320384 0.8220806463189513 0.7822246578247244 1.0 16.80486166928857 -5.766230123083814 2.120380283978071 0.8533105022182979 0.9434492682045645 0.06962042293878434 0.09663431539009637 0.6487952569501877 5.952994964357816 0.027995117321690258 0.05377118001548883 1.7130493598404803e-06 5.766230123083814 0.09013876598626669 DS(ph)QGTY(ph)S(ph)S(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 DSQGTYSSR 9 0 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 4 DS(0.995)QGT(0.01)Y(0.997)S(0.998)S(0.999)R 57.59 0.032938999999999996 0.0 1972.9 2982.9 4016.4 3004.0 4530.6 3198.7 4412.7 4531.8 4640.5 2957.2 True False 1944.76608421445 2975.993278318831 3686.1870957523483 3224.924181050236 4264.119015502316 3061.899057533889 4641.168014493075 4742.363972149273 4117.838023368647 3468.3480797786847 0.5607182553426258 0.8580434287059011 1.06280771449778 0.9298156087194162 1.2294380256592958 0.8828119286485423 1.3381494324494756 1.3673264225694104 1.187262041943439 1.0 11.760032977850129 -4.462409092347769 0.5803034140552201 1.2013475691092992 3.234094873348247e-12 0.6066869243638253 0.14779519815526426 3.6602467490218107 0.7169171222845263 0.07674055388562837 3.1995718586926847 3.448187773840839e-05 4.462409092347769 -1.201347569106065 DS(ph)QGTYSSR ddPTM_PC-9_AZD4547_30min_R2 1 DSQGTYSSR 9 0 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 DS(0.901)QGT(0.084)YS(0.012)S(0.002)R 73.082 0.030551 16687000.0 13782.0 15163.0 20406.0 23758.0 14970.0 26127.0 22010.0 28652.0 20971.0 32428.0 True False 18164.389316591652 20064.143221373884 20135.40310695645 18280.960157440986 12891.673901009353 24493.27455976606 23968.8473609802 24224.491757460164 22079.484246854965 31292.705590315007 0.5804672039036942 0.6411763649987386 0.643453569357975 0.5841923800637707 0.41197057454179625 0.782715143919887 0.765956375737561 0.7741258322181501 0.7055792661689341 1.0 14.933538779994132 -6.860854725301208 10.993245602585693 0.7898351721449461 0.5807916113608866 0.6042276203170044 0.09390697282502365 0.29815317418906484 30.7483550106153 0.03257960534473655 0.028737319385131646 1.377670232651943e-07 6.860854725301208 -0.2090435607840595 DS(ph)QGTYSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSQGTYSSR 9 0 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 DS(0.808)QGT(0.192)YSSR 94.402 0.0057588 10231000.0 15921.0 19372.0 22316.0 17479.0 30349.0 18227.0 19533.0 22646.0 22407.0 14553.0 True False 18616.11084591642 21295.124134912126 22848.09807390129 16499.708297682577 24402.331312119393 17271.14403320032 17682.692833326408 22051.566495420386 22734.65998512071 17191.343698515386 1.0828770090568356 1.2387120232347595 1.3290466687530893 0.9597683919906426 1.4194545662086167 1.004641890481884 1.0285811943166172 1.2827133749483888 1.3224481101546492 1.0 14.069394691754772 DS(ph)QGTYSSR ddPTM_PC-9_Lapatinib_30min_R1 1 DSQGTYSSR 9 0 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 DS(0.978)QGT(0.022)YSSR 75.73899999999999 0.025533 12296000.0 9712.6 12026.0 17193.0 15323.0 22099.0 12360.0 15131.0 19393.0 21890.0 13023.0 True False 9574.096542927304 11998.154535875243 15779.457906899252 16449.904536029542 20799.180268305663 11831.391612567253 15914.409143448393 20294.069577627175 19424.51768808094 15274.00819794327 0.6268227971893133 0.7855275694752384 1.033092145978031 1.0769867557256263 1.3617368799832377 0.7746094842452955 1.0419274978254467 1.3286669297689577 1.2717367593593776 1.0 13.89879108271203 -5.151992441372447 1.6573088493954713 1.1291259457194749 0.5928478574968455 0.5142587432443575 0.16322511876306317 0.44735719680735564 1.914821967239094 0.0494959297106737 0.30490512757639626 7.047053338220371e-06 5.151992441372447 -0.5362780882226293 DS(ph)SKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVK ddPTM_PC-9_AZD4547_30min_R2 1 DSSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVK 45 2 Q12906-7;Q12906-4;Q12906-6 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 DS(0.25)S(0.25)KGEDS(0.25)AEET(0.25)EAKPAVVAPAPVVEAVSTPSAAFPSDATAENVK 45.894 0.0005171 7212100.0 31804.0 29876.0 29660.0 34509.0 36060.0 37773.0 37612.0 33654.0 32939.0 36816.0 True False 41917.010435704586 39532.832742977385 29266.68902050026 26553.483208735186 31053.691440908286 35411.0483387317 40959.395135901264 28453.54759198534 34680.088293698725 35527.083045918254 1.1798607383985744 1.1127520008293885 0.823785307188701 0.7474152373955155 0.8740850297439795 0.9967339084090697 1.1529062232033467 0.8008973761006366 0.9761591811203638 1.0 15.116631620485855 -5.119536627540024 5.183392736210411 0.918002248622922 1.1640156670572517 0.39576397548068887 0.11213983983832802 0.22315769523972256 8.350068684241041 0.03092422508085031 0.0880386430540783 7.5938737473366075e-06 5.119536627540024 0.24601341843432967 DS(ph)SKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVK ddPTM_PC-9_Lapatinib_30min_R1 1 DSSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVK 45 2 Q12906-7;Q12906-4;Q12906-6 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 DS(0.25)S(0.25)KGEDS(0.25)AEET(0.25)EAKPAVVAPAPVVEAVSTPSAAFPSDATAENVK 48.538000000000004 0.00035318 6888500.0 38271.0 31274.0 35558.0 33378.0 34834.0 36302.0 32694.0 37843.0 32585.0 28416.0 True False 37725.24852195817 31201.58697446883 32634.55849784933 35832.72946574391 32785.13260627899 34749.44808409521 34386.73534702942 39601.32393266362 28914.93416473813 33327.66773806003 1.131949850750466 0.9362067342875233 0.9792031880040867 1.075164627401248 0.9837211791702583 1.0426606613222897 1.0317774294106976 1.1882416808734295 0.8675954882890716 1.0 15.024432741088098 DS(ph)SPSSSPSPK ddPTM_PC-9_Lapatinib_30min_R1 1 DSSPSSSPSPK 11 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 DS(0.395)S(0.234)PS(0.234)S(0.068)S(0.068)PSPK 126.66 0.00039959 1967000.0 18350.0 25176.0 20409.0 16568.0 25811.0 21291.0 19014.0 20387.0 24107.0 22270.0 True False 18088.325635022124 25117.706518808835 18731.050801018242 17786.4659892278 24292.847726378463 20380.4335617451 19998.45188378347 21334.254446402585 21391.81580203597 26119.339827090284 0.6925261417312467 0.9616516606119355 0.7171333933023413 0.6809692016327362 0.9300712761959844 0.7802813431221205 0.7656568663746091 0.8167991452936825 0.8190029282382149 1.0 14.672830812413146 -9.220985905235782 1.1332678952541986 1.0004767611650731 0.7947438817954404 0.3314764138119414 0.0877402845424353 4.648608325854188 6.514579280151508 0.0855987311843253 0.025213015432655007 6.01193248529211e-10 9.220985905235782 -0.2057328793696327 DS(ph)SVEVR ddPTM_PC-9_AZD4547_30min_R2 1 DSSVEVR 7 0 O15371-2;O15371-3;O15371;B0QYA6;B0QYA5 O15371-2 EIF3D Eukaryotic translation initiation factor 3 subunit D 1 DS(0.921)S(0.079)VEVR 90.37 0.015974000000000002 25072000.0 86468.0 87685.0 115630.0 153440.0 115850.0 113990.0 110970.0 108530.0 91371.0 128450.0 True False 113963.02535387091 116027.46147636812 114096.67064870016 118066.77862436832 99766.22721656185 106862.18728012124 120846.11502262509 91759.18227129514 96200.6845224065 123953.00459713704 0.9194051061873423 0.9360600967557992 0.9204832994531177 0.9525124381462176 0.8048713909018561 0.862118571691238 0.9749349393779543 0.7402739656817848 0.7761061124340706 1.0 16.919433716937306 -6.249065448023588 24.805252825075033 0.8526121199010884 0.9315661613676444 0.17403489440490794 0.07632712868761889 1188.1105048010554 2381730.555325316 0.022746346084189874 0.02914373818463037 5.635527222320618e-07 6.249065448023588 0.07895404146655594 DS(ph)SVEVR ddPTM_PC-9_Lapatinib_30min_R1 1 DSSVEVR 7 0 O15371-2;O15371-3;O15371;B0QYA6;B0QYA5 O15371-2 EIF3D Eukaryotic translation initiation factor 3 subunit D 1 DS(0.932)S(0.068)VEVR 82.287 0.022701 24210000.0 72927.0 60509.0 52333.0 54748.0 62284.0 59120.0 51420.0 62859.0 57988.0 39782.0 True False 71887.047606826 60368.89512816186 48030.382751221885 58774.350553974095 58620.577575055446 56591.57541545112 54082.27600000769 65779.65861806151 51456.78079928909 46658.26569381701 1.540714095088027 1.2938521016687023 1.0294078023904498 1.2596771371586293 1.2563814085962401 1.2128949624235699 1.159114579073917 1.4098179098581112 1.1028438377234402 1.0 15.509845062323114 -11.683159996572815 0.032320726302546225 4.034023328983765e-31 2.0920328963142834 0.31016923068035884 0.13106818472904433 1105.6734775923376 4.743544110513944 200.87039509459038 115.3607653725137 2.0741492482285462e-12 11.683159996572815 2.0920328963142834 DS(ph)VPIQGITLEEVS(ph)EIIGR ddPTM_PC-9_AZD4547_30min_R2 1 DSVPIQGITLEEVSEIIGR 19 0 Q14934-2;Q14934-9;Q14934-4;Q14934-6;Q14934;Q14934-12;Q14934-22;Q14934-19 Q14934-2 NFATC4 Nuclear factor of activated T-cells, cytoplasmic 4 2 DS(1)VPIQGITLEEVS(1)EIIGR 85.166 0.021514 0.0 9657.4 11074.0 14799.0 21932.0 16757.0 14599.0 12151.0 16109.0 12406.0 17110.0 True False 12728.252313601235 14653.453936127038 14602.755590505169 16875.916246022196 14430.579796874652 13686.122222146618 13232.415460393937 13619.724197994045 13061.755832649022 16510.984107878674 0.7708960429274229 0.8874973072704211 0.8844267243608489 1.0221023856457705 0.873998769703176 0.8289101444665496 0.8014310578907119 0.8248886988810689 0.7910949309445608 1.0 14.01113849163854 -6.606283438928334 5.617878974605151 0.8360304530959015 0.8970908534822593 0.04405856939219677 0.07883642963175735 0.4725820810473793 24.425603335640268 0.026133452803884474 0.02614038855916654 2.4758057148287035e-07 6.606283438928334 0.06106040038635774 DS(ph)YGGPPR ddPTM_PC-9_AZD4547_30min_R2 1 DSYGGPPR 8 0 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 DS(1)YGGPPR 89.029 0.028094 0.0 32164.0 38486.0 48834.0 54073.0 50121.0 42642.0 40916.0 49921.0 51206.0 48180.0 True False 42391.48294723943 50925.84686525064 48186.429252431226 41607.3052695221 43162.56430143549 39975.588999025655 44557.44473520519 42206.85652045817 53912.64462087913 46493.23286485068 0.9117774853485782 1.0953389069175927 1.03641812546145 0.8949109946918234 0.9283622936461101 0.8598152147266054 0.9583640884841766 0.9078064466531633 1.1595804657765065 1.0 15.504733125387599 -8.251418025359104 24.946421766139395 1.0797902387913008 0.9517196756778462 0.32626014189712205 0.07504692193632764 744.6297916604668 1853638.3416759511 0.0545011511335468 0.020085357761824192 5.6050820531375135e-09 8.251418025359104 -0.12807056311345455 DS(ph)YGGPPR ddPTM_PC-9_Lapatinib_30min_R1 2 DSYGGPPR 8 0 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 DS(1)YGGPPR;DS(1)YGGPPR 91.087 0.008988 3945300.0 50529.0 69853.0 55239.0 53031.0 74342.0 68772.0 74333.0 66508.0 81162.0 62610.0 True False 49808.44719411626 69691.25967025557 50697.462648706314 56931.07664623001 69969.34972199556 65830.7818753621 78181.5990258377 69598.2044793909 72020.68088625059 73432.05507741905 0.67829297629766 0.9490577323047874 0.6903996162882304 0.7752891647415813 0.9528447712409414 0.8964856261472872 1.064679436567739 0.9477905038339709 0.9807798625589267 1.0 16.164122355506347 -6.3067783935582975 4.004744022163322 0.9747545008665841 0.7788510646169088 0.6065275043039557 0.07918692195328604 0.16036889673775143 5.534709366267921 0.02433510335445901 0.02872541641236054 4.934255188277635e-07 6.3067783935582975 -0.19590343624967532 DS(ph)YYVYTQQELK ddPTM_PC-9_AZD4547_30min_R2 1 DSYYVYTQQELK 12 0 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 DS(1)YYVYTQQELK 228.03 1.4567e-15 6183700.0 27991.0 46342.0 34729.0 26023.0 27934.0 41123.0 48062.0 43379.0 33774.0 32755.0 True False 36891.55575103154 61321.14523279752 34268.47076847453 20023.79940134215 24055.84627593822 38551.57230915369 52339.424891568866 36675.772300253535 35559.22468901244 31608.257419846082 1.167149307252484 1.9400356184866874 1.0841619742997335 0.6334989979159583 0.7610620843917235 1.219667753178575 1.655878215504097 1.160322500955895 1.1249979464760254 1.0 14.948013880434235 -5.307525493282242 21.994191522614514 1.0838993138911341 1.5535921702455862 0.2708582560647469 0.3107929700775694 132.9806558508697 63463.40508451116 0.08797417747671857 0.18313642931487917 4.9257742798341215e-06 5.307525493282242 0.469692856354452 DS(ph)YYVYTQQELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DSYYVYTQQELK 12 0 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 DS(1)YYVYTQQELK;DS(1)YYVYTQQELK 194.77 4.2685999999999995e-36 2135700.0 22815.0 28526.0 20979.6 23887.0 22239.0 17216.3 22056.0 16470.300000000003 12805.0 16125.400000000001 True False 26677.128883209778 31357.872758233705 21479.833229576074 22548.6888326989 17881.427593997272 16313.446920435988 19966.696008388244 16037.972076725351 12992.248900320015 19048.807371403844 1.4004618957540411 1.64618561922718 1.1276208956693896 1.1837323142103422 0.9387163849869653 0.8564025349390539 1.0481861472525749 0.8419410078555168 0.6820505161821332 1.0 14.217413054264227 -5.67956929512882 1.0053752259278161 0.8757992934115475 1.5695965984814504 0.7665803546220317 0.13036927190739428 0.3070193698966414 0.5629811541747513 0.04923377400537337 0.1686121509658067 2.0913691859401222e-06 5.67956929512882 0.6937973050699029 DS(ph)YYVYTQQELK ddPTM_PC-9_Lapatinib_30min_R1 2 DSYYVYTQQELK 12 0 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 DS(0.999)Y(0.001)YVYTQQELK;DS(0.999)YYVYT(0.001)QQELK 124.81 0.00031141 11490400.0 30484.0 62867.0 43889.0 42327.0 54921.0 49886.0 65333.0 58403.0 46230.0 43727.0 True False 30049.29256991907 62721.435324036975 40280.615836439334 45439.86877873279 51690.65475884046 47752.49206994584 68715.6230631758 61116.616590633734 41023.09057651815 51285.15368743496 0.5859257584184885 1.222994001466821 0.78542449305964 0.8860238394852604 1.0079067925559293 0.9311172656511969 1.3398735915265738 1.191701929238978 0.7999018746543982 1.0 15.646253626406796 -7.041208715456149 24.95315134171362 1.1040804084374494 0.9149144260951616 0.15938799993852626 0.19900495600197318 880.6193081781164 533239.5381444726 0.07345180179420836 0.05690203312866748 9.094760869338275e-08 7.041208715456149 -0.18916598234228776 DSAAPS(ph)PIPGADNLSADPVVSPPTSIPFK ddPTM_PC-9_AZD4547_30min_R2 1 DSAAPSPIPGADNLSADPVVSPPTSIPFK 29 0 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 DS(0.034)AAPS(0.656)PIPGADNLS(0.306)ADPVVS(0.005)PPTSIPFK 76.972 2.515e-06 9290100.0 50901.0 50583.0 72101.0 93092.0 76190.0 75585.0 75769.0 77056.0 55003.0 71121.0 True False 67086.45919342853 66932.96554552235 71144.89363004346 71631.07765706262 65612.33363513033 70858.65800129813 82512.29421599784 65148.76577072626 57910.34628914999 68631.07543754755 0.9774939233536478 0.9752574197446399 1.0366279877805997 1.043712009470768 0.9560149424561444 1.0324573460280047 1.2022585059312065 0.9492604531603166 0.843791910879305 1.0 16.066574341199626 -7.985675545027803 24.999474141145505 0.9134392770026828 1.0309662537733644 0.28921174716663434 0.07311753980909112 260.36158500311694 454390.85416894715 0.040621395415889175 0.019501201363104407 1.033533254787108e-08 7.985675545027803 0.11752697677068158 DSAAPS(ph)PIPGADNLSADPVVSPPTSIPFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DSAAPSPIPGADNLSADPVVSPPTSIPFK 29 0 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 DS(0.039)AAPS(0.761)PIPGADNLS(0.199)ADPVVS(0.001)PPTSIPFK;DS(0.056)AAPS(0.86)PIPGADNLS(0.084)ADPVVSPPTSIPFK 85.615 3.0403e-08 16187500.0 111770.0 118190.0 127201.0 156282.0 173624.0 165034.0 165903.0 140618.0 141947.0 135267.0 True False 130690.45344187386 129923.12210950161 130233.95425247877 147526.02621308045 139603.62357031275 156379.32651424702 150187.4668062949 136926.92649708648 144022.7063376593 159789.8363270173 0.8178896508436856 0.813087522310292 0.815032778342353 0.9232503743927842 0.8736702332218894 0.978656278201634 0.9399062559831983 0.8569188732183138 0.9013258267748028 1.0 17.28581612083203 -5.760247447528153 24.93535212227728 0.9195973065406646 0.8151117119723108 0.5984404386703435 0.04094130428140511 21.842599041784613 456924.78219983535 0.011391865858888253 0.018401725636103514 1.736810965750412e-06 5.760247447528153 -0.10448559456835382 DSAAPSPIPGADNLS(ph)ADPVVSPPTSIPFK ddPTM_PC-9_AZD4547_30min_R2 1 DSAAPSPIPGADNLSADPVVSPPTSIPFK 29 0 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 DS(0.017)AAPS(0.372)PIPGADNLS(0.611)ADPVVSPPTSIPFK 86.51899999999999 2.7077e-08 7768600.0 39082.0 32585.0 51775.0 62699.0 62814.0 45290.0 46013.0 54214.0 45368.0 54440.0 True False 51509.26304390036 43117.464015595055 51088.429670815996 48244.71423989359 54093.36034856387 42458.00914042193 50108.06786100781 45836.47201378419 47766.05985939235 52534.072170246385 0.9804924864186249 0.8207523657382761 0.9724818115232812 0.918350933914806 1.0296814641222618 0.8081994672491577 0.9538203644031885 0.872509404282284 0.9092396208045246 1.0 15.680965798653123 -12.005378206814706 2.0766803936795166 1.8357557570623435 0.916834693062298 0.11877248216711533 0.06656530109261613 7926315.273091172 353506.63216348673 31384512.895428088 0.017321052658984884 9.876925846028882e-13 12.005378206814706 -0.9189210640000455 DSAAPSPIPGADNLS(ph)ADPVVSPPTSIPFK ddPTM_PC-9_Lapatinib_30min_R1 2 DSAAPSPIPGADNLSADPVVSPPTSIPFK 29 0 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 DSAAPS(0.001)PIPGADNLS(0.997)ADPVVS(0.002)PPTSIPFK;DS(0.001)AAPS(0.045)PIPGADNLS(0.953)ADPVVSPPTSIPFK 106.88 1.3472999999999998e-11 14976700.0 127839.0 113444.0 133410.0 111781.0 123464.0 131310.0 117849.0 119932.0 127249.0 111826.0 True False 126015.99241719872 113181.3273879788 122441.5447774928 120001.74763048453 116202.09025956337 125694.17739856035 123950.64458041445 125504.47855329158 112916.87762862559 131154.9751012214 0.9608174781013333 0.8629587043924861 0.9335638597239346 0.9149614609577017 0.8859907157153751 0.9583637776725847 0.9450700934886619 0.956917405965203 0.8609423892725364 1.0 17.000913008823737 -6.770076504279117 24.999101426744836 0.941616779265492 0.9103533699961204 0.13752976919267723 0.04048436469601491 406.8013613921373 1177429.572964463 0.013483439191777113 0.01207086738381621 1.697944520262219e-07 6.770076504279117 -0.031263409269371656 DSAATTDEER ddPTM_PC-9_AZD4547_30min_R2 2 DSAATTDEER 10 0 Q16531;Q16531-2;F5GY55 Q16531 DDB1 DNA damage-binding protein 1 0 ; 128.86 0.001224 4700300.0 16291.5 12256.8 19634.3 19765.3 20068.9 17694.8 15418.3 20727.9 18348.6 18456.6 False True 21471.85811574901 16218.570905212386 19373.936353176287 15208.71545584091 17282.679649429952 16588.34135875333 16790.498830795135 17524.87933475703 19318.469536590674 17810.44005175181 1.2055770690313217 0.9106215712854971 1.0877853830046547 0.8539213748592921 0.9703679189964793 0.9313830152737703 0.9427335193295038 0.9839666669568509 1.0846710963040205 1.0 14.12043554184171 -4.752324534878721 24.998758499587893 0.9708284219588936 1.205577523408675 0.5047286272552713 0.06877521074157042 290.0875836577249 795548.7209314987 0.016500322282809187 0.19889503224888516 1.7687867045596953e-05 4.752324534878721 0.23474910144978134 DSAATTDEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DSAATTDEER 10 0 Q16531;Q16531-2;F5GY55 Q16531 DDB1 DNA damage-binding protein 1 0 ; 130.66 0.00021875 1883200.0 11605.099999999999 12097.5 14573.7 13580.5 16582.8 15836.8 13991.400000000001 13293.5 13228.5 16439.2 False True 13569.614218826995 13298.459850407768 14921.192279065026 12819.62861357505 13333.519380625838 15006.290328906955 12666.033303036049 12944.559710627522 13421.941786636742 19419.496827364415 0.6987624004606428 0.6847994038480252 0.7683614262363 0.6601421616398756 0.6866047817385927 0.7727435196859107 0.6522328264030034 0.6665754435195805 0.6911580617126807 1.0 14.245218199561416 -10.164418559139875 6.679606144551263 1.00000000025461 0.6981058717293794 0.8420468596286985 0.039248451126674105 1.6705498332577257e-10 0.0 0.03798399229875097 0.009212471313552828 6.848278930661611e-11 10.164418559139875 -0.3018941285252307 DSAATTDEER ddPTM_PC-9_Lapatinib_30min_R1 2 DSAATTDEER 10 0 Q16531;Q16531-2;F5GY55 Q16531 DDB1 DNA damage-binding protein 1 0 ; 143.03 0.00058986 5136600.0 13939.4 19361.4 20567.8 13013.800000000001 20468.5 16323.4 16691.2 17277.1 18193.9 18508.8 False True 13740.621599827113 19316.569867860864 18876.79487800397 13970.87826476417 19264.583072619324 15625.286233703917 17555.388665331167 18079.857139154476 16144.711391739433 21708.021418574244 0.6329743892766796 0.8898355817602447 0.8695769418143394 0.6435813746162113 0.8874407621569684 0.7197932014354059 0.8087051475962743 0.8328652708848275 0.7437209997372389 1.0 14.405940616801749 -11.112733550156886 2.7451465797414003 1.0159577289562927 0.7863905664571292 0.3472587682838538 0.08982021861443687 32061406.70476375 31238584.427146498 3710495.323209255 0.021330734672517587 7.713765815281521e-12 11.112733550156886 -0.22956716249916342 DSAIPVES(ph)DTDDEGAPR ddPTM_PC-9_AZD4547_30min_R2 2 DSAIPVESDTDDEGAPR 17 0 C9JA08;Q96D46 C9JA08 NMD3 60S ribosomal export protein NMD3 1 DSAIPVES(0.958)DT(0.042)DDEGAPR;DSAIPVES(0.822)DT(0.178)DDEGAPR 288.41 4.546999999999999e-97 81297000.0 57995.0 60949.0 81762.0 100893.0 77787.0 77480.0 66770.0 89114.0 67048.0 70699.0 True False 76436.20362906184 80649.57232734398 80677.78245765816 77633.67763131124 66987.61775135712 72635.16335173092 72712.40064937054 75343.47893600108 70592.02039879511 68223.84952910092 1.1203736546185061 1.1821316575363117 1.1825451512120408 1.1379257864685068 0.9818797709851232 1.0646594094745176 1.0657915252694006 1.1043568994719841 1.0347117743434289 1.0 16.057988540831126 -6.08401685460512 6.561436471953635 1.0497062376614423 1.163257021593253 0.6998344897325401 0.03654268390643469 0.14075016105863644 9.163834243317572 0.010884476018883496 0.014179533679934879 8.241061315236063e-07 6.08401685460512 0.11355078393181062 DSAIPVES(ph)DTDDEGAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSAIPVESDTDDEGAPR 17 0 C9JA08;Q96D46 C9JA08 NMD3 60S ribosomal export protein NMD3 1 DSAIPVES(0.616)DT(0.384)DDEGAPR 192.23 3.5147e-09 33265000.0 60496.0 70066.0 78776.0 87028.0 94986.0 66551.0 73215.0 70156.0 71584.0 60750.0 True False 70736.77794953588 77021.68942993751 80654.31859964355 82152.1033085829 76374.17516270645 63060.948403660295 66279.54516930293 68314.47933642629 72630.78057637713 71763.49410326466 0.9856930579181196 1.0732711720963102 1.1238906300128777 1.1447617529655045 1.064248279951464 0.8787329712920365 0.9235830277986388 0.9519391466380471 1.012085343445854 1.0 16.130962515106667 -6.638709094464573 6.7965308780860925 0.9488795445554021 1.0865803042040019 0.5881758408116695 0.05233361988551974 0.15459621767228499 8.608444228780517 0.0182871324641557 0.01825341769139074 2.2976872034979325e-07 6.638709094464573 0.13770075964859974 DSAIPVES(ph)DTDDEGAPR ddPTM_PC-9_Lapatinib_30min_R1 2 DSAIPVESDTDDEGAPR 17 0 C9JA08;Q96D46 C9JA08 NMD3 60S ribosomal export protein NMD3 1 DSAIPVES(0.616)DT(0.384)DDEGAPR;DSAIPVES(0.5)DT(0.5)DDEGAPR 222.09 2.613e-23 76413000.0 63390.0 56699.0 57520.0 55789.0 56976.0 48647.0 43181.0 44125.0 56328.0 45621.0 True False 62486.046975697696 56567.7169490762 52790.92763362096 59891.90916664831 53624.78369912586 46566.48121169576 45416.700893744295 46175.20858623213 49983.74747986406 53506.52906383858 1.1678209756634683 1.0572114831366715 0.9866259044879582 1.119338335237394 1.0022100972975876 0.8702953083751208 0.848806709916797 0.8629826937781845 0.934161650071312 1.0 15.707427324769782 -6.585791188050088 3.86318707447256 0.8918610496634504 1.0735025363621498 0.6637022362310592 0.05981450990210636 0.13405821206930701 4.062514931189447 0.02029581693350925 0.020616936254966793 2.5954269623534106e-07 6.585791188050088 0.1816414866986994 DSALAEAPEGLS(ph)PAPPAR ddPTM_PC-9_AZD4547_30min_R2 3 DSALAEAPEGLSPAPPAR 18 0 Q9H9J4-2;Q9H9J4;C9JPC9 Q9H9J4-2 USP42 Ubiquitin carboxyl-terminal hydrolase 42 1 DSALAEAPEGLS(1)PAPPAR;DSALAEAPEGLS(1)PAPPAR;DSALAEAPEGLS(1)PAPPAR 229.22 3.3043e-35 56501900.0 86278.2 85924.7 121911.0 144576.0 127435.0 118421.0 94254.0 118451.0 96236.0 108834.0 True False 113712.87290195582 113698.17892591086 120294.38048476756 111246.23687693365 109742.84993821802 111016.11614965553 102642.42340580786 100147.11968319525 101322.83849031213 105023.75478649154 1.0827347882688907 1.0825948772927994 1.1454016353664036 1.0592483300858184 1.0449335977495775 1.0570571998244225 0.9773257832428024 0.9535663611226788 0.9647611504301746 1.0 16.680356155057687 -6.949408234763481 1.1181045291316012 0.9649989638869909 1.0960780649192936 0.7988709904926468 0.0261467587856411 0.20916692216483473 0.5425745207066688 0.015708455460738027 0.011827087196720763 1.1235483472884445e-07 6.949408234763481 0.1310791010323027 DSALAEAPEGLS(ph)PAPPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DSALAEAPEGLSPAPPAR 18 0 Q9H9J4-2;Q9H9J4;C9JPC9 Q9H9J4-2 USP42 Ubiquitin carboxyl-terminal hydrolase 42 1 DSALAEAPEGLS(1)PAPPAR;DSALAEAPEGLS(1)PAPPAR;DSALAEAPEGLS(1)PAPPAR 224.99 7.246899999999999e-35 59323000.0 68982.0 71564.0 76941.0 84041.0 92305.0 81596.0 76529.0 68534.0 74496.0 63834.0 True False 80659.2901433959 78668.40097000076 78775.56524036734 79332.45523459809 74218.49786698665 77316.96211845143 69279.6190980206 66735.05511777541 75585.36306741447 75406.59889033403 1.0696582438454891 1.0432561888172474 1.0446773412355184 1.0520625038396645 0.9842440709323693 1.0253341651291776 0.9187474321547896 0.8850028525332392 1.0023706702027553 1.0 16.202403159937138 -6.719589984550892 1.3177869794909076 0.9458292604206141 1.051918129271532 0.531958030964552 0.038753550432868454 0.31295144443245904 1.1401959354793252 0.018161275086866383 0.017021235496510686 1.9072605042295545e-07 6.719589984550892 0.10608886885091795 DSALAEAPEGLS(ph)PAPPAR ddPTM_PC-9_Lapatinib_30min_R1 4 DSALAEAPEGLSPAPPAR 18 0 Q9H9J4-2;Q9H9J4;C9JPC9 Q9H9J4-2 USP42 Ubiquitin carboxyl-terminal hydrolase 42 1 DSALAEAPEGLS(1)PAPPAR;DSALAEAPEGLS(1)PAPPAR;DSALAEAPEGLS(1)PAPPAR;DSALAEAPEGLS(1)PAPPAR 205.15 4.0028999999999996e-20 79811400.0 160327.0 125733.0 134833.0 142024.0 143651.0 148333.0 117917.3 125346.0 143923.0 104304.4 True False 158040.70757962918 125441.87296351232 123747.55121043116 152468.91873817507 135201.73060873232 141989.14337111154 124022.48082021988 131170.03275807019 127712.87616362164 122333.27656312345 1.2918864925364837 1.025410881550163 1.0115608335445667 1.246340513568291 1.1051917712591375 1.1606747351187454 1.0138082155939379 1.0722350977854092 1.0439749490215144 1.0 16.90045736728453 -7.262776761703487 24.991747874464767 1.0385241549930198 1.1323499863556186 0.282775850841836 0.08323023405862175 189.47066206019116 3540617.775258619 0.03357374641572426 0.024043462904993516 5.46038466483576e-08 7.262776761703487 0.09382583136259881 DSAS(ph)PSTSSFCLGVSVAASSHVPIQK ddPTM_PC-9_AZD4547_30min_R2 1 DSASPSTSSFCLGVSVAASSHVPIQK 26 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 DS(0.165)AS(0.727)PS(0.039)T(0.039)S(0.014)S(0.014)FCLGVSVAASSHVPIQK 66.98 0.0045052 0.0 4825.7 4065.8 11292.0 20400.0 17235.0 13116.0 7540.8 17293.0 8881.7 11423.0 True False 6360.172219204488 5379.990338947564 11142.260701938265 15697.09517685815 14842.217747755241 12295.854446583673 8211.916591534731 14620.764203607372 9351.168529650084 11023.084246890601 0.5769866288555827 0.4880657916104701 1.0108115344470203 1.4240202492588223 1.3464668703717786 1.1154640725940288 0.7449744924022652 1.3263768901822197 0.8483259603398084 1.0 13.428240324432695 -5.33118514430686 4.499388836193746 1.128059032667588 0.5303149004104118 0.5520084420375739 0.20602269775918317 0.14844509004172635 5.789353736621078 0.05629410815551197 0.12673417357111913 4.664604809101903e-06 5.33118514430686 -0.597744132257176 DSAS(ph)PSTSSFCLGVSVAASSHVPIQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSASPSTSSFCLGVSVAASSHVPIQK 26 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 DS(0.142)AS(0.506)PS(0.16)T(0.16)S(0.016)S(0.016)FCLGVSVAASSHVPIQK 56.57 0.024011 0.0 4800.0 3437.3 8101.9 8605.4 9131.0 9536.6 6917.4 9390.0 9253.6 5204.8 True False 5612.545195678587 3778.5324276756896 8295.080022626853 8123.267337083229 7341.846097431952 9036.483907775184 6262.133794360936 9143.5224495274 9388.916393908736 6148.3890388258715 0.9128480908147589 0.6145564966392006 1.3491469017729765 1.3212025598553359 1.1941089041486532 1.4697319656761405 1.0184999281627738 1.4871411668630348 1.5270530759552736 1.0 12.585992738992568 -5.2683679486410036 24.98421706248184 1.3068335159736604 0.7637022834865705 0.567903985732582 0.18547754383657436 316.16218580029016 1140074.8270606212 0.046363494254161114 0.100006679267647 5.390537248585271e-06 5.2683679486410036 -0.5431312324870898 DSASPST(ph)SSFCLGVSVAASSHVPIQK ddPTM_PC-9_Lapatinib_30min_R1 1 DSASPSTSSFCLGVSVAASSHVPIQK 26 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 DS(0.068)AS(0.26)PS(0.295)T(0.335)S(0.021)S(0.021)FCLGVSVAASSHVPIQK 74.321 0.00018316 1236800.0 3243.5 2793.4 8997.7 3614.3 5180.3 6930.5 4008.1 5181.1 10002.0 2887.8 True False 3197.247095214948 2786.932053925986 8257.943838126406 3880.1076789513513 4875.604938861661 6634.09867078458 4215.619806216082 5421.83282053546 8875.469434270706 3386.9523822483725 0.9439893846669637 0.8228435889836536 2.438163548270645 1.1456044375727557 1.439525682266921 1.958722155515113 1.244664621891617 1.6007998367358993 2.6204884015460745 1.0 11.725771988536659 -5.2099385037036114 24.996977888366455 1.669044136848682 0.8834152455751717 0.28528042711238066 0.5046866428170969 434.4602358934872 210872.31119711226 0.12299484845804216 0.3254133193996093 6.1668231817637435e-06 5.2099385037036114 -0.7856288912735102 DSAYFS(ph)DNDSEPEKR ddPTM_PC-9_AZD4547_30min_R2 1 DSAYFSDNDSEPEKR 15 1 Q8IWU2 Q8IWU2 LMTK2 Serine/threonine-protein kinase LMTK2 1 DS(0.003)AYFS(0.961)DNDS(0.036)EPEKR 66.26100000000001 0.014775 8744800.0 30110.0 37961.0 37600.0 36078.0 28036.0 25495.0 41689.0 35907.0 38367.0 27067.0 True False 39684.353673093494 50231.15088218522 37101.39943259645 27760.774499543557 24143.685336586368 23900.793619674503 45399.240237705744 30358.398210774878 40395.001292217086 26119.392568553605 1.5193444322618512 1.92313625787228 1.4204541447592702 1.0628415047050555 0.9243586072385969 0.9150593206539505 1.7381430337076091 1.1622934235968725 1.5465520948159635 1.0 14.672833725571413 -5.49857037613368 5.296863612327455 1.2010127147193999 1.7161595625797286 0.3849289158045921 0.2663809106922012 0.18925179922597724 15.373005571653643 0.0736625171159598 0.1476496165779801 3.1727044948170024e-06 5.49857037613368 0.5151468478603287 DSAYFS(ph)DNDSEPEKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSAYFSDNDSEPEKR 15 1 Q8IWU2 Q8IWU2 LMTK2 Serine/threonine-protein kinase LMTK2 1 DS(0.001)AYFS(0.949)DNDS(0.05)EPEKR 67.153 0.013941 5653300.0 16655.0 16671.0 12833.0 13485.0 23692.0 15336.0 14024.0 12545.0 12934.0 11772.0 True False 19474.362548755602 18325.986705199248 13138.987389423519 12729.47916895987 19049.72267444504 14531.75316251497 12695.545195032495 12215.707042526208 13123.135281276007 13906.170412899275 1.4004116137316502 1.317831305173722 0.9448314668455291 0.9153835161657509 1.3698755378960867 1.0449859832751227 0.91294330632222 0.8784378933825661 0.9436915334435331 1.0 13.763437553779193 -1.5228787453381036 0.5202308295669195 0.9736070302885698 17.709386263959814 0.4772374409230131 0.1414712207754221 111.24148184588185 1.115950443201383 0.08100351852841373 2054.33446307843 0.02999999999600966 1.5228787453381036 16.735779233671245 DSAYFS(ph)DNDSEPEKR ddPTM_PC-9_Lapatinib_30min_R1 2 DSAYFSDNDSEPEKR 15 1 Q8IWU2 Q8IWU2 LMTK2 Serine/threonine-protein kinase LMTK2 1 DS(0.001)AYFS(0.998)DNDS(0.001)EPEKR;DS(0.007)AYFS(0.972)DNDS(0.021)EPEKR 77.795 0.0057557 23103000.0 87351.0 93699.0 56871.0 45636.0 51010.0 50468.0 50352.0 39959.0 68176.0 31460.0 True False 86105.35872178867 93482.04572234955 52195.285908408485 48992.22367723322 48009.69208951863 48309.60128665408 52958.98018577185 41815.64101750141 60497.30095489299 36897.819082185 2.3336164809632893 2.533538513865296 1.4145900003507093 1.3277810151355975 1.3011525690064067 1.309280669923901 1.4352875455270877 1.1332821846289238 1.6395901562675905 1.0 15.171247925041042 -5.289192606248168 6.167862467219637 1.3248994906258316 2.436805116261644 0.8761143807413458 0.16754153769888663 0.045760352856567994 6.231708266358314 0.040031745167142654 0.08871453377876168 5.1381572773846784e-06 5.289192606248168 1.1119056256358124 DSAYISS(ph)SPLGSHQVFDFR ddPTM_PC-9_AZD4547_30min_R2 1 DSAYISSSPLGSHQVFDFR 19 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 DSAYIS(0.003)S(0.559)S(0.437)PLGSHQVFDFR 168.68 3.4874e-08 82771000.0 36136.0 32300.0 61942.0 70263.0 70855.0 58651.0 45985.0 71624.0 47777.0 57770.0 True False 47626.496324506996 42740.34333907382 61120.608607816204 54064.950902528624 61018.00629632709 54983.5436982753 50077.57591525098 60556.15655578409 50302.39468132138 55747.489883819464 0.8543253951660061 0.7666774491218675 1.0963831507964679 0.9698185696827367 1.094542667723545 0.9862963124055224 0.8982929279796298 1.0862579944314286 0.9023257331613327 1.0 15.766619226489253 -5.252734955134475 24.978299728623007 1.0048914485969522 0.8105014065909383 0.5439264465431242 0.07095947159429139 439.69919674326013 1261757.8196489068 0.017207092822249158 0.04406419005870537 5.588111266168342e-06 5.252734955134475 -0.19439004200601395 DSAYISS(ph)SPLGSHQVFDFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSAYISSSPLGSHQVFDFR 19 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 DSAYISS(0.588)S(0.412)PLGSHQVFDFR 190.63 1.3393999999999999e-11 47955000.0 29324.0 31544.0 51273.0 57976.0 78777.0 73501.0 77421.0 64745.0 66290.0 58268.0 True False 34287.97402459975 34675.47985296654 52495.542773935325 54727.792680728024 63341.21235542623 69646.47816888441 70087.12240049976 63045.51235299801 67259.36584164097 68831.52715076577 0.4981434444930558 0.5037732168431304 0.7626671228571062 0.7950977545631741 0.9202354644360311 1.0118397927788758 1.0182415718742341 0.9159394678968213 0.9771592847899306 1.0 16.070781898631736 -5.521630645083792 0.9642216448447665 0.9834785389470776 0.4201701312670575 0.9511268533242965 0.04170173109290326 0.1649905562296316 0.24839634618304965 0.016428489539575184 0.07634598519263233 3.0086339711778722e-06 5.521630645083792 -0.5633084076800201 down DSAYISS(ph)SPLGSHQVFDFR ddPTM_PC-9_Lapatinib_30min_R1 2 DSAYISSSPLGSHQVFDFR 19 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 DS(0.014)AY(0.001)IS(0.116)S(0.533)S(0.332)PLGS(0.005)HQVFDFR;DSAYIS(0.054)S(0.728)S(0.217)PLGSHQVFDFR 91.565 0.00052713 86764000.0 108615.0 112689.0 169416.0 129934.0 203655.0 224070.0 193180.0 199331.0 259820.0 171905.0 True False 107066.13018244869 112428.0755440916 155487.27044467212 139489.77980711777 191676.4133011354 214487.0484326818 203181.91516300067 208592.6459535915 230556.33557410628 201618.55020098534 0.5310331319996042 0.5576276361079703 0.7711952609999089 0.6918499298207733 0.9506883821456954 1.0638259635280007 1.0077540730277887 1.0345905460864289 1.143527395392309 1.0 17.621268856587044 -5.984024791256209 0.8401825706153195 1.0708588335948708 0.5130421280646386 0.912001175522576 0.061910663948790176 0.1926697424013518 0.2712248271791454 0.029600208636650905 0.07157657592099748 1.0374691912602076e-06 5.984024791256209 -0.5578167055302322 DSAYISSS(ph)PLGSHQVFDFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSAYISSSPLGSHQVFDFR 19 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 DSAYISS(0.208)S(0.792)PLGSHQVFDFR 162.83 6.745000000000001e-07 48021000.0 21295.0 21853.0 41856.0 37540.0 53922.0 49765.0 53416.0 42065.0 51836.0 40279.0 True False 24899.82290457824 24022.42141855435 42854.00577976397 35436.75550632213 43356.371182315816 47155.23579372437 48356.04978164972 40960.83832155162 52594.00343592259 47581.26385161145 0.5233115072821872 0.5048714446398794 0.9006487493356613 0.7447628044693474 0.9112068001709343 0.9910463063945568 1.0162834247626238 0.8608606624929822 1.105351123079539 1.0 15.538105972628935 -4.88776095989543 0.5737254735843296 1.002678305690183 0.1548466493735879 0.7938651235205865 0.08830109371039635 1.4688102302297097 0.40051665025470035 0.0466546651997226 0.8177133786450238 1.2949083760930321e-05 4.88776095989543 -0.847831656316595 DSAYISSSPLGS(ph)HQVFDFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DSAYISSSPLGSHQVFDFR 19 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 DSAYISSS(0.001)PLGS(0.999)HQVFDFR;DSAYIS(0.006)S(0.039)S(0.131)PLGS(0.824)HQVFDFR 127.49 3.283e-05 21857000.0 20646.0 20057.9 30344.0 34876.0 43031.0 37723.0 42309.0 40134.0 38590.0 34206.0 True False 24140.960022912528 22049.11575395695 31067.51604026085 32922.01078951757 34599.38445061812 35744.73947245382 38301.18522936605 39080.525025487994 39154.3057448926 40407.27702545298 0.5974409017392059 0.5456719031096298 0.7688594314507033 0.8147545000070071 0.8562661727694145 0.8846114389231875 0.9478784033192763 0.9671655182523372 0.9689914447892363 1.0 15.302327513693015 -5.252776652674881 0.4814022854442697 0.9894822906444646 0.3539929396177214 0.9430995502402049 0.03563976863926822 0.6426372703333543 0.15990587722211216 0.025245079025503 0.220652741634596 5.587574765431019e-06 5.252776652674881 -0.6354893510267432 DSAYQSITHYRPVS(ph)ASR ddPTM_PC-9_AZD4547_30min_R2 1 DSAYQSITHYRPVSASR 17 1 P50402;Q5HY57 P50402 EMD Emerin 1 DSAYQSITHY(0.018)RPVS(0.95)AS(0.032)R 88.57 0.0012755000000000002 32871000.0 0.0 4242.0 5607.4 18289.0 23328.0 14536.0 10964.0 27386.0 14619.0 16112.0 True False 0.0 5613.143543168768 5533.042212189929 14072.75361223327 20089.30987059091 13627.061622105843 11939.774759917618 23154.1229676743 15391.730494719992 15547.923784111113 0.0 0.36102206449616164 0.3558701656258638 0.905121082894337 1.2920895516043611 0.8764553911713757 0.7679337077867098 1.4892099607110363 0.9899540741542134 1.0 13.92443432026855 -5.745599847877245 2.523840328334507 1.0745168676343784 0.19866829483826562 0.7649266903631315 0.20803012589172687 0.13415865319912257 1.7411682163826703 0.062388563327304816 0.11534175006246906 1.7963880282946532e-06 5.745599847877245 -0.8758485727961127 down DSAYQSITHYRPVS(ph)ASR ddPTM_PC-9_Lapatinib_30min_R1 2 DSAYQSITHYRPVSASR 17 1 P50402;Q5HY57 P50402 EMD Emerin 1 DSAYQSITHY(0.02)RPVS(0.66)AS(0.319)R;DSAYQSIT(0.001)HY(0.005)RPVS(0.906)AS(0.087)R 79.695 0.0029363 34786000.0 40718.0 28797.0 31613.0 12676.8 21617.8 27303.0 21913.9 21091.0 36985.0 13195.6 True False 40137.353853233326 28730.32231578241 29013.901169708963 13609.094160565115 20346.283506230055 26135.314336401592 23048.49451646381 22070.964856480954 32819.35983068404 15476.441877968224 2.59344842759831 1.856390670563755 1.8747139296282462 0.8793425690396314 1.3146615783305067 1.688715955674993 1.4892631457670462 1.4261007168514932 2.1206011103498312 1.0 13.917786205356668 -4.779019852771816 1.4862176837205092 1.4591195245523507 3.021719243570063 0.5045323927225648 0.34515190265652285 0.9861344527444383 2.0112179628148277 0.09898021601536267 2.3042686892107422 1.663336613030582e-05 4.779019852771816 1.562599719017712 DSCIS(ph)PSEPETK ddPTM_PC-9_AZD4547_30min_R2 2 DSCISPSEPETK 12 0 Q8TDB6 Q8TDB6 DTX3L E3 ubiquitin-protein ligase DTX3L 1 DS(0.001)CIS(0.543)PS(0.452)EPET(0.004)K;DS(0.001)CIS(0.919)PS(0.08)EPETK 125.84 0.00028118 34818000.0 77397.0 67051.0 84697.0 101282.0 99172.0 88921.0 96751.0 96627.0 81157.0 80762.0 True False 102007.63604239169 88723.92449623035 83573.8624399634 77932.99969130126 85403.67963332676 83360.75581310336 105361.65156847751 81695.51741756611 85446.79333470082 77934.54696203956 1.308888548387632 1.1384415250331292 1.0723596363583232 0.9999801465357968 1.0958385332620881 1.0696252055421174 1.3519248609964611 1.0482580652885356 1.0963917372397165 1.0 16.24997536999861 -4.776208928433228 3.3638918856101014 1.0990584204377136 1.3378341278646884 0.3228918563432126 0.09370367112835783 0.40747169566226776 7.281590906876359 0.024367946782456244 0.25579237560679796 1.6741372958398087e-05 4.776208928433228 0.23877570742697474 DSCIS(ph)PSEPETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DSCISPSEPETK 12 0 Q8TDB6 Q8TDB6 DTX3L E3 ubiquitin-protein ligase DTX3L 1 DSCIS(0.714)PS(0.285)EPET(0.001)K;DS(0.007)CIS(0.937)PS(0.057)EPETK 126.5 0.00026178 21081000.0 52405.0 58348.0 57054.0 63062.0 64172.0 61517.0 75277.0 55474.0 49668.0 48196.0 True False 61276.13145407004 64140.40383150179 58414.38373849992 59528.84058976249 51597.95726255647 58290.94022551076 68146.21760171556 54017.86627956149 50394.30053737564 56933.55328067393 1.076274497605794 1.1265835370453547 1.0260098021728192 1.0455844956012879 0.9062838043532296 1.023841598962656 1.196942991872734 0.9487878968885265 0.8851423744613173 1.0 15.796991522145802 -1.5228787474843042 0.2775477674104287 0.9810792663682824 1.9408581524408128 0.16570707796698114 0.083216661361376 105.37912603037759 1.4823121873784877 0.10043089050100268 48.90082610740452 0.02999999984775538 1.5228787474843042 0.9597788860725305 DSCIS(ph)PSEPETK ddPTM_PC-9_Lapatinib_30min_R1 2 DSCISPSEPETK 12 0 Q8TDB6 Q8TDB6 DTX3L E3 ubiquitin-protein ligase DTX3L 1 DSCIS(0.92)PS(0.08)EPETK;DSCIS(0.913)PS(0.087)EPETK 176.87 0.00095557 32870000.0 154006.0 183873.0 187339.0 179011.0 209054.0 200350.0 199231.0 196310.0 211240.0 168073.0 True False 151809.84619875852 183447.25336562333 171936.71056945217 192176.0661031901 196757.85473597763 191781.49753866094 209546.20633523003 205431.27926488896 187447.92674418533 197124.19410680467 0.7701228501484998 0.9306176453724854 0.8722253062264617 0.9748984236763265 0.9981415808826157 0.972896799439804 1.0630161725439695 1.042141377905055 0.9509128374299067 1.0 17.588745331365125 -3.3911388786701937 0.48494510996490814 1.0173651650455597 1.6605727502554793e-18 0.7459665711727381 0.040773597354165116 8.038438244205544 0.506653452585805 0.023996204565417196 6.252608150817395 0.0004063133775144824 3.3911388786701937 -1.0173651650455597 DSCISPS(ph)EPETK ddPTM_PC-9_Lapatinib_30min_R1 1 DSCISPSEPETK 12 0 Q8TDB6 Q8TDB6 DTX3L E3 ubiquitin-protein ligase DTX3L 1 DSCIS(0.332)PS(0.642)EPET(0.025)K 113.24 0.0018437000000000002 0.0 13690.0 19457.0 17984.0 17324.0 23958.0 19823.0 18168.0 20463.0 18609.0 16556.0 True False 13494.778089561472 19411.94851193452 16505.424940247554 18598.06475116986 22548.837543240294 18975.216499669972 19108.65014329328 21413.785683854225 16513.05845854263 19417.68254051669 0.6949736695614134 0.9997047006732032 0.8500203309950889 0.9577901334190305 1.161252765163411 0.9772132415944347 0.9840850010510478 1.10279821699487 0.850413453000207 1.0 14.245083407968284 -4.120818891425182 1.0486103793544799 1.0044074488751495 6.904403111773571e-22 0.4487150055807654 0.09369690762100544 5.7967504535800405 1.9408194773458716 0.028945976740682357 9.09300298457683 7.571485737062366e-05 4.120818891425182 -1.0044074488751495 DSCPLDCK ddPTM_PC-9_Lapatinib_30min_R1 1 DSCPLDCK 8 0 A0A087X2D0;P84103-2;P84103 A0A087X2D0 SRSF3 Serine/arginine-rich splicing factor 3 0 94.11399999999999 0.031481 5089000.0 32783.0 34236.0 30890.0 28882.0 31137.0 29595.0 30047.0 30420.0 29593.0 30679.0 False True 32315.508408334103 34156.72864545357 28350.34343884825 31006.07862752758 29305.58287769734 28329.290839314548 31602.686638899886 31833.42425366983 26259.924711894902 35981.82427280211 0.8981064485037994 0.949277290292141 0.7879073396586417 0.861715025687689 0.8144551720199691 0.7873222498262283 0.878295841792204 0.8847084575901294 0.7298108209522945 1.0 15.134980712403603 -5.251223605814942 24.772829573567883 0.8378264805240269 0.9236918743078403 0.17143385752054352 0.0701940399533444 948.5722165528429 2300234.77746392 0.016622358074844752 0.04292131063099976 5.607591828185645e-06 5.251223605814942 0.08586539378381342 DSDAGS(ph)STPTTSTR ddPTM_PC-9_AZD4547_30min_R2 1 DSDAGSSTPTTSTR 14 0 P51532;A0A2R8Y7Y7;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8YG32;A0A2R8Y440;A0A2R8Y7F3;K7EP28;A0A2R8YF80;A0A2R8Y6N0;A0A2R8Y526;A0A2R8YF58;A0A2R8Y4C5;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8Y523;A0A2R8Y5K3;K7EQF0;A0A2R8YFK5;A0A0A0MT49;P51532-5;P51532-2;P51532-3;P51532-4 P51532 SMARCA4 Transcription activator BRG1 1 DSDAGS(0.471)S(0.3)T(0.192)PT(0.029)T(0.007)STR 146.84 0.00019891 61547000.0 19141.0 17038.0 21839.0 28142.0 27472.0 19676.0 19841.0 25944.0 19328.0 23500.0 True False 25227.439842467025 22545.200303750466 21549.400590650883 21654.296689565785 23657.987001237736 18445.656609559337 21606.81056288997 21934.95093381076 20349.638621105947 22677.27215284331 1.1124547817054782 0.9941760257493631 0.9502642313153606 0.9548898361150875 1.0432465969356663 0.8133983878324004 0.9527958396963047 0.967265850406109 0.8973583102919405 1.0 14.46895948860149 -1.522881721785665 0.8916190147622441 0.9406746294225758 82.22947792117661 0.43005865300438095 0.05741801243150902 800.3819233297862 1.8392152571284244 0.018962086848278985 132320.97283338875 0.029999794391000707 1.522881721785665 81.28880329175404 DSDAGS(ph)STPTTSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DSDAGSSTPTTSTR 14 0 P51532;A0A2R8Y7Y7;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8YG32;A0A2R8Y440;A0A2R8Y7F3;K7EP28;A0A2R8YF80;A0A2R8Y6N0;A0A2R8Y526;A0A2R8YF58;A0A2R8Y4C5;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8Y523;A0A2R8Y5K3;K7EQF0;A0A2R8YFK5;A0A0A0MT49;P51532-5;P51532-2;P51532-3;P51532-4 P51532 SMARCA4 Transcription activator BRG1 1 DSDAGS(0.381)S(0.381)T(0.237)PT(0.002)TSTR;DS(0.002)DAGS(0.902)S(0.048)T(0.048)PTTSTR;DSDAGS(0.326)S(0.238)T(0.238)PT(0.016)T(0.175)S(0.003)T(0.003)R;DS(0.002)DAGS(0.902)S(0.045)T(0.045)PT(0.005)TSTR 167.22 0.00034994 133297700.0 53363.0 52166.8 51621.8 63900.0 63179.0 61035.0 59691.0 54572.2 56242.0 44492.8 True False 62396.301932707574 57345.575145629475 52852.659488766716 60319.890166595156 50799.52848424629 57834.217154023245 54036.63635458388 53139.73757402543 57064.43285058949 52558.99243518902 1.187167010662334 1.0910706710434535 1.005587379817827 1.1476607022285705 0.9665240167396218 1.100367691129908 1.0281140077260225 1.011049396343595 1.085721590286499 1.0 15.681649998765836 -4.836886754649147 3.031220470779997 1.0458842165173372 1.201157638319945 0.41827597634007796 0.051599709083705626 0.30186763868037453 4.365878308535038 0.012215145856642393 0.10709766593718589 1.455838651293721e-05 4.836886754649147 0.15527342180260773 DSDAGSS(ph)TPTTSTR ddPTM_PC-9_AZD4547_30min_R2 1 DSDAGSSTPTTSTR 14 0 P51532;A0A2R8Y7Y7;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8YG32;A0A2R8Y440;A0A2R8Y7F3;K7EP28;A0A2R8YF80;A0A2R8Y6N0;A0A2R8Y526;A0A2R8YF58;A0A2R8Y4C5;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8Y523;A0A2R8Y5K3;K7EQF0;A0A2R8YFK5;A0A0A0MT49;P51532-5;P51532-2;P51532-3;P51532-4 P51532 SMARCA4 Transcription activator BRG1 1 DSDAGS(0.086)S(0.581)T(0.332)PT(0.001)TSTR 204.18 1.1242e-10 82328000.0 24922.0 21707.0 28751.0 35705.0 32720.0 27660.0 23867.0 33297.0 25731.0 27558.0 True False 32846.67759019715 28723.36324647913 28369.74295443032 27473.763886750992 28177.392788311674 25930.41582742484 25991.116763494505 28151.71373894145 27091.08812912239 26593.20280800238 1.2351531264339841 1.0801016881590413 1.066804294287311 1.033112261246082 1.059571236745977 0.9750768275125515 0.9773594008643932 1.0586056122006517 1.0187222774449034 1.0 14.698769921203866 -1.522878745280375 0.7554538661234629 1.014750857399932 40.719822301198974 0.8426204587714713 0.028132213210316476 149.2803352002128 0.6292902350072137 0.010878360104069364 10093.925843812043 0.029999999999997418 1.522878745280375 39.70507144379904 DSDAGSS(ph)TPTTSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSDAGSSTPTTSTR 14 0 P51532;A0A2R8Y7Y7;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8YG32;A0A2R8Y440;A0A2R8Y7F3;K7EP28;A0A2R8YF80;A0A2R8Y6N0;A0A2R8Y526;A0A2R8YF58;A0A2R8Y4C5;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8Y523;A0A2R8Y5K3;K7EQF0;A0A2R8YFK5;A0A0A0MT49;P51532-5;P51532-2;P51532-3;P51532-4 P51532 SMARCA4 Transcription activator BRG1 1 DS(0.004)DAGS(0.087)S(0.491)T(0.295)PT(0.111)T(0.013)STR 162.67 0.0005514 2138300.0 8184.9 9331.5 8744.7 10230.0 11754.0 9512.7 10702.0 9518.0 9948.1 7620.7 True False 9570.441910856172 10257.869650264945 8953.206812459433 9656.846266107488 9450.888076795003 9013.837265848728 9688.229084229733 9268.162585154601 10093.57214254382 9002.272584571989 1.0631139882675744 1.139475566185897 0.9945496238142528 1.0727120485839656 1.049833582354732 1.0012846402025817 1.0761981481024392 1.0295358753120065 1.121224896015934 1.0 13.136073534172972 -5.253585067451263 24.998537228226123 1.0451993117840075 1.1012947723358995 0.23784999712724697 0.041493376659452075 828.8449561492238 2638015.331640265 0.009920244219572721 0.025201416375270635 5.577183483348262e-06 5.253585067451263 0.05609546055189196 DSDAGSS(ph)TPTTSTR ddPTM_PC-9_Lapatinib_30min_R1 3 DSDAGSSTPTTSTR 14 0 P51532;A0A2R8Y7Y7;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8YG32;A0A2R8Y440;A0A2R8Y7F3;K7EP28;A0A2R8YF80;A0A2R8Y6N0;A0A2R8Y526;A0A2R8YF58;A0A2R8Y4C5;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8Y523;A0A2R8Y5K3;K7EQF0;A0A2R8YFK5;A0A0A0MT49;P51532-5;P51532-2;P51532-3;P51532-4 P51532 SMARCA4 Transcription activator BRG1 1 DS(0.001)DAGS(0.145)S(0.427)T(0.427)PT(0.001)TSTR;DSDAGS(0.203)S(0.397)T(0.397)PT(0.002)T(0.002)STR;DS(0.003)DAGS(0.207)S(0.653)T(0.137)PTTSTR 163.62 5.2765e-05 70666600.0 52057.6 52385.0 55320.1 46788.4 45440.6 50347.4 45715.0 44242.4 57634.0 42760.4 True False 51315.24907780537 52263.705751024776 50771.89491976134 50229.37501752691 42767.87324765691 48194.15906752176 48081.89901478707 46298.063418821905 51142.652007074365 50151.47816534846 1.023205116878509 1.042116955729846 1.0123708567944374 1.0015532314306195 0.8527739323385854 0.9609718562756324 0.9587334366548873 0.923164483132044 1.0197636017518372 1.0 15.61400460302679 -6.0155770344587625 24.422943394735196 0.9474281285404451 1.0240933436006996 0.3779103819554944 0.04280030664725413 504.843761194768 791537.3960014749 0.01227203375327192 0.016364208361524912 9.647681675969286e-07 6.0155770344587625 0.07666521506025448 DSDLSHVQNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSDLSHVQNK 10 0 O60506-2;O60506;O60506-4;O60506-3;F6UXX1 O60506-2 SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0 116.52 0.00086768 5289200.0 69787.0 67507.0 89516.0 105630.0 110300.0 104280.0 90916.0 90249.0 91369.0 77707.0 False True 81600.56074392132 74208.64882177951 91650.40093132026 99711.89355708032 88687.50679517514 98811.37322555175 82303.77830516073 87880.05937671982 92705.09877183453 91794.66397172658 0.8889466687198166 0.8084200716137085 0.9984284158341626 1.0862493443822867 0.966151004403606 1.076439184482296 0.896607436032566 0.957354769595186 1.0099181669251316 1.0 16.486122671693174 -5.271233964107844 24.44942691926919 0.9984373902080386 0.8486833705082405 0.5439051191791402 0.05501933341827451 332.1031551469866 829003.9303844193 0.014593342604521446 0.030996457037167358 5.3550808965928925e-06 5.271233964107844 -0.14975401969979807 DSDLSHVQNK ddPTM_PC-9_Lapatinib_30min_R1 3 DSDLSHVQNK 10 0 O60506-2;O60506;O60506-4;O60506-3;F6UXX1 O60506-2 SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0 ;; 137.05 9.7787e-05 21709400.0 329505.0 314670.0 404153.0 336301.0 391046.0 350995.0 349926.0 327616.0 402326.0 315988.0 False True 324806.19827618345 313941.4009482665 370925.1004156961 361033.6974072479 368045.4431060159 335983.7620593076 368043.456078932 342838.2353810095 357011.8091993993 370606.1047724564 0.876418909709021 0.8471026162427068 1.0008607403902199 0.9741709398686627 0.9930906112083268 0.9065791354559415 0.9930852496477417 0.9250744414787886 0.9633187489412683 1.0 18.49952712064929 -5.254803554695205 24.999677206500902 0.966447856833386 0.8617607521434252 0.660189823879157 0.030861895307662333 301.8536410695464 1137189.779640889 0.007682184452182369 0.01935564988380437 5.561557674505747e-06 5.254803554695205 -0.10468710468996079 DSDQVAQS(ph)DGEESPAAEEQLLGEHIK ddPTM_PC-9_AZD4547_30min_R2 1 DSDQVAQSDGEESPAAEEQLLGEHIK 26 0 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;D6RHZ5;H0Y8V7 D6REX3 SEC31A Protein transport protein Sec31A 1 DS(0.002)DQVAQS(0.597)DGEES(0.401)PAAEEQLLGEHIK 62.666000000000004 0.011685 0.0 4473.5 4207.9 3958.6 2954.0 2163.6 5396.1 4549.9 5246.8 5227.2 3019.0 True False 5895.9799454195845 5568.021385030609 3906.1063774967097 2273.000938845048 1863.2214864544962 5058.681013968447 4954.832285675773 4436.0276194695625 5503.499120459699 2913.305728912083 2.0238109192959035 1.911238264413079 1.3407814836362433 0.780213664596697 0.6395557692293009 1.736405816857921 1.7007594625250877 1.5226783702945281 1.8890908241596989 1.0 11.50844139377539 DSDQVAQS(ph)DGEESPAAEEQLLGEHIK ddPTM_PC-9_Lapatinib_30min_R1 2 DSDQVAQSDGEESPAAEEQLLGEHIK 26 0 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;D6RHZ5;H0Y8V7 D6REX3 SEC31A Protein transport protein Sec31A 1 DS(0.015)DQVAQS(0.985)DGEESPAAEEQLLGEHIK;DS(0.001)DQVAQS(0.991)DGEES(0.008)PAAEEQLLGEHIK 152.31 3.4395999999999997e-10 4922000.0 11774.7 14930.6 13032.4 12921.3 15132.2 13694.599999999999 15365.800000000001 14711.2 12454.6 11981.0 True False 11606.790618784478 14896.029113033332 11960.926378518798 13871.575506193212 14242.153747049868 13108.913881671804 16161.365938563167 15394.736057875996 11051.831795247735 14051.899886320987 0.8259944002364595 1.0600722488447327 0.8511963844947632 0.9871672598305861 1.0135393692146986 0.9328926328626106 1.150119632882929 1.0955626059407249 0.7865008920257318 1.0 13.77847758268389 -5.9780640473340885 24.193223583693506 1.0052330544856787 0.9258520221394562 0.1038370820652964 0.10764984989569587 392.51739623700223 432903.5159219611 0.02987428789993113 0.04430593748167666 1.0518067477772762e-06 5.9780640473340885 -0.07938103234622251 DSDQVAQS(ph)DGEESPAAEEQLLGEHIKEEK ddPTM_PC-9_AZD4547_30min_R2 2 DSDQVAQSDGEESPAAEEQLLGEHIKEEK 29 1 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;D6RHZ5;H0Y8V7 D6REX3 SEC31A Protein transport protein Sec31A 1 DS(0.001)DQVAQS(0.858)DGEES(0.141)PAAEEQLLGEHIKEEK;DS(0.025)DQVAQS(0.97)DGEES(0.005)PAAEEQLLGEHIKEEK 79.829 1.1136e-06 6186800.0 48397.0 57197.0 58099.0 35680.0 46495.0 59099.0 62819.0 66034.0 65666.0 57846.0 True False 63786.23927986398 75684.81170170293 57328.569298787785 27454.52725050483 40039.97181211954 55403.53018745414 68409.76930347182 55829.9626103631 69136.97070020398 55820.82914695209 1.1426960196514173 1.3558525170319051 1.027010350345504 0.4918330248773077 0.7172944655965539 0.9925243145636661 1.2255240624136645 1.0001636210631513 1.2385514826051087 1.0 15.7685159335004 DSDQVAQS(ph)DGEESPAAEEQLLGEHIKEEK ddPTM_PC-9_Lapatinib_30min_R1 2 DSDQVAQSDGEESPAAEEQLLGEHIKEEK 29 1 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;D6RHZ5;H0Y8V7 D6REX3 SEC31A Protein transport protein Sec31A 1 DS(0.003)DQVAQS(0.997)DGEESPAAEEQLLGEHIKEEK;DS(0.056)DQVAQS(0.781)DGEES(0.163)PAAEEQLLGEHIKEEK 107.84 8.6227e-12 5184600.0 65518.0 80071.0 76986.0 70199.0 78733.0 61158.0 75136.0 75408.0 67928.0 74697.0 True False 64583.701305470306 79885.60051904767 70656.50825455376 75361.66863699924 74102.07973503377 58542.414906261205 79026.17443672857 78911.7309704384 60277.23332644876 87608.27692250405 0.7371872107768919 0.9118499224646587 0.8065049415028973 0.8602117435052645 0.8458342332264164 0.6682292696847155 0.9020400493281362 0.9007337404916844 0.6880312619293768 1.0 16.418779556578606 -11.10111128709242 6.153541374818163 1.0004586896418588 0.8193315005568793 0.3029201609815102 0.08448912237669202 0.0005128387065726363 3.515031043673714e-05 0.078907915609361 0.019090321972579826 7.922982796162992e-12 11.10111128709242 -0.1811271890849795 DSDQVAQSDGEES(ph)PAAEEQLLGEHIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSDQVAQSDGEESPAAEEQLLGEHIK 26 0 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;D6RHZ5;H0Y8V7 D6REX3 SEC31A Protein transport protein Sec31A 1 DS(0.004)DQVAQS(0.385)DGEES(0.611)PAAEEQLLGEHIK 50.783 0.011006 1636300.0 5150.1 9708.7 6585.5 6046.2 7064.5 4588.3 7403.0 4116.8 4645.0 4825.4 True False 6021.910210888391 10672.51557343699 6742.523295647831 5707.451016044876 5680.2619379375765 4347.681470759481 6701.734246921389 4008.738362110155 4712.92433752335 5700.206822154619 1.0564371432074058 1.8723032174827106 1.1828559043580857 1.001270865096 0.9965010244646696 0.7627234601140495 1.175700190539438 0.7032619143799581 0.8267988310890645 1.0 12.476798550585716 -5.601006640773072 3.2634747002896622 0.9163739595205267 1.4778110293631175 0.4761756800984104 0.22534077639732805 0.17971184719214872 3.817154742470073 0.05957358035972269 0.11555155295057994 2.5060709325461372e-06 5.601006640773072 0.5614370698425908 DSDQVAQSDGEES(ph)PAAEEQLLGEHIK ddPTM_PC-9_Lapatinib_30min_R1 1 DSDQVAQSDGEESPAAEEQLLGEHIK 26 0 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;D6RHZ5;H0Y8V7 D6REX3 SEC31A Protein transport protein Sec31A 1 DSDQVAQS(0.268)DGEES(0.732)PAAEEQLLGEHIK 102.46 9.4496e-10 1882900.0 11118.0 18612.0 14670.0 14698.0 18059.0 14574.0 16316.0 20636.0 18672.0 16434.0 True False 10959.455281208508 18568.905057517863 13463.889227837613 15778.939951090664 16996.805125360064 13950.703993653326 17160.762645198873 21594.823895421785 16568.962735123238 19274.59500307146 0.56859587864036 0.9633875603901849 0.698530331023407 0.8186392475990415 0.8818242418401827 0.7237871400893374 0.8903306472828227 1.1203775691256077 0.8596270236797675 1.0 14.234412926164527 -7.523490402950404 24.902431136864696 0.9950722374154868 0.7891996740502735 0.4133824299465334 0.11619995595229154 19.785841367629587 805409.5676528063 0.05005773210656546 0.02924051068510702 2.995777792464115e-08 7.523490402950404 -0.2058725633652133 DSEGFNS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 DSEGFNSPK 9 0 O43303-2;O43303;I3L262 O43303-2 CCP110 Centriolar coiled-coil protein of 110 kDa 1 DSEGFNS(1)PK;DSEGFNS(1)PK 87.667 0.010713 10922000.0 99721.0 102583.0 77798.0 92175.0 86045.0 90074.0 93315.0 88128.0 80128.0 82169.0 True False 98298.96025340816 102345.47536618076 71401.74874896451 98953.856986786 80984.00227097882 86221.7449927495 98146.39410619832 92222.74860708119 71103.14085475332 96371.80216668961 1.0199971157889653 1.061985695661878 0.7408987602562873 1.026792638116597 0.8403288145520484 0.8946781429241715 1.018414016336846 0.9569474320669856 0.7378002616550605 1.0 16.556323463502665 -5.145930603939769 19.44378223757027 0.9062075877182202 1.0410360192863526 0.23608457015923445 0.09977641449026992 5.8131402077637615 964.4993665056114 0.02421877907239382 0.06407836516622284 7.146105048040414e-06 5.145930603939769 0.1348284315681324 DSENLASPS(ph)EYPENGER ddPTM_PC-9_AZD4547_30min_R2 4 DSENLASPSEYPENGER 17 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;P52948-4;P52948-3 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 DSENLAS(0.002)PS(0.998)EYPENGER;DSENLAS(0.079)PS(0.921)EYPENGER;DSENLAS(0.012)PS(0.988)EYPENGER;DSENLAS(0.011)PS(0.989)EYPENGER 248.01 1.8710999999999999e-47 326603200.0 147947.0 157507.8 222571.0 250955.0 220570.0 205876.8 175797.0 224789.0 175071.0 199870.7 True False 194991.0685112308 208419.1161170953 219619.56311469202 193101.2019660997 189947.66281533954 193003.29115038287 191442.5924360856 190053.0251873419 184324.89564546975 192873.28762890652 1.010980166866855 1.0806012521448765 1.138672782605573 1.001181679122055 0.9848313633809366 1.0006740359075876 0.9925822014525225 0.9853776410604309 0.9556787148260566 1.0 17.557293822728603 -5.907857398799054 8.117295847620754 0.9873703333384285 1.0768685207301598 0.6328748490140395 0.03092211284417564 0.15743947757628576 12.217440515461227 0.00885554862064712 0.013177095097327196 1.2363533251479488e-06 5.907857398799054 0.08949818739173132 DSENLASPS(ph)EYPENGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DSENLASPSEYPENGER 17 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;P52948-4;P52948-3 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 DSENLAS(0.016)PS(0.984)EYPENGER;DSENLAS(0.013)PS(0.987)EYPENGER;DS(0.001)ENLAS(0.005)PS(0.995)EYPENGER;DSENLAS(0.003)PS(0.997)EYPENGER 162.82 3.1185e-05 196252800.0 56346.9 62211.7 72453.2 79051.0 94205.0 86013.0 96626.0 89913.0 88444.0 73860.0 True False 65885.31726799616 68387.66643319804 74180.75906829104 74622.02875679992 75746.20650625083 81502.32686276725 87472.88576834071 87552.87902069822 89737.32618039098 87250.23332456178 0.7551305567620621 0.783810699723897 0.8502069993594898 0.855264518081158 0.8681490423582345 0.9341215920831648 1.0025518836488458 1.0034687093043138 1.0285052860154251 1.0 16.412871368931775 -6.465058371632018 0.6078443000081157 1.0293723053939652 0.7583790215319152 0.9515497653027739 0.020674712747434543 0.1875107249556589 0.15083477519881835 0.016683348397583255 0.02572336505240551 3.427217197152811e-07 6.465058371632018 -0.27099328386205 DSENLASPS(ph)EYPENGER ddPTM_PC-9_Lapatinib_30min_R1 4 DSENLASPSEYPENGER 17 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;P52948-4;P52948-3 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 DS(0.106)ENLAS(0.386)PS(0.507)EYPENGER;DSENLAS(0.002)PS(0.997)EYPENGER;DSENLAS(0.396)PS(0.604)EYPENGER;DSENLAS(0.001)PS(0.999)EYPENGER 215.64 2.5134e-22 304120900.0 70003.0 58886.0 68243.0 60014.7 80162.0 83603.0 81677.0 77752.0 92385.0 84768.0 True False 69004.74438302209 58749.65308494504 62632.32396559801 64428.381241170304 75447.02876455575 80027.49457811161 85905.83541136968 81364.64176763123 81979.6284428213 99420.03585374013 0.6940728173196103 0.5909236763037731 0.6299768796878965 0.6480422249691488 0.7588714700882646 0.8049433284840343 0.8640696482723904 0.8183928025064209 0.8245785443431548 1.0 16.60124900310762 -6.5689105544772275 1.2632816367050725 0.8661159460575147 0.6276182152008954 0.797610109335235 0.05328549493655976 0.19305741473760044 0.6444779930035388 0.02311511661599515 0.024914686986675833 2.698295105091608e-07 6.5689105544772275 -0.2384977308566193 DSENT(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 1 DSENTPVK 8 0 Q92922 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 1 DSENT(1)PVK 84.18799999999999 0.03463 5013700.0 17389.0 56483.0 29573.0 55067.0 60009.0 28384.0 108980.0 106030.0 42094.0 51891.0 True False 17141.02967124794 56352.21708380519 27141.622095081217 59116.81087812691 56479.388602233324 27170.08248633568 114622.45115676454 110956.54088154565 37352.93045052898 60860.290209588726 0.28164554608954717 0.925927511842964 0.44596603140753627 0.9713527601419961 0.9280170766148405 0.44643366623406194 1.8833701049080016 1.823135257808286 0.6137488060259678 1.0 15.893213592845537 -7.249272657968588 24.99537606354637 1.398658165103183 0.6940586818963989 0.3824326750762359 0.40847058674101533 750.1089012400317 1541029.7681347895 0.15439634893726945 0.11868028994193865 5.632839049193435e-08 7.249272657968588 -0.7045994832067842 DSENT(ph)PVKGGTVADLDEQDEETVTAGGK ddPTM_PC-9_AZD4547_30min_R2 1 DSENTPVKGGTVADLDEQDEETVTAGGK 28 1 Q92922 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 1 DS(0.24)ENT(0.623)PVKGGT(0.136)VADLDEQDEETVTAGGK 95.68 1.0949e-09 4731300.0 9226.8 9648.6 9943.0 7813.7 8441.8 14090.0 11292.0 11961.0 9801.6 9737.1 True False 12160.730470637618 12767.321261343272 9811.149323359212 6012.372185461595 7269.801786074866 13208.95007261085 12296.966124497423 10112.702286436574 10319.692565637013 9396.207092742583 1.2942169484568182 1.3587739324311467 1.0441606093310907 0.6398722512305434 0.7736953554046181 1.4057746857041011 1.308715953482477 1.0762536613573999 1.0982827925969947 1.0 13.197862795413243 -6.768085437118755 24.99967331032247 1.190753113794589 1.0208313388697783 0.104126667695287 0.22669196845742817 416.8833204274757 1568130.6341670887 0.089828147788837 0.08102511990091085 1.7057467908479364e-07 6.768085437118755 -0.16992177492481075 DSENT(ph)PVKGGTVADLDEQDEETVTAGGK ddPTM_PC-9_Lapatinib_30min_R1 2 DSENTPVKGGTVADLDEQDEETVTAGGK 28 1 Q92922 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 1 DS(0.114)ENT(0.824)PVKGGT(0.062)VADLDEQDEETVTAGGK;DS(0.067)ENT(0.537)PVKGGT(0.296)VADLDEQDEET(0.083)VT(0.017)AGGK 79.373 1.1214000000000001e-05 8927900.0 56947.0 82458.0 64729.0 71360.0 88894.0 71805.0 69210.0 76209.0 65638.0 64244.0 True False 56134.92533719922 82267.0735672045 59407.231481165676 76608.05244998158 83665.42969232834 68734.06753563049 72793.35515286923 79749.94835463271 58245.157241217756 75348.48980025097 0.7450039872864479 1.091821133844815 0.7884329419030744 1.016716494956564 1.1103796494677676 0.9122155960636327 0.9660891060437256 1.0584146884171137 0.7730102805726539 1.0 16.2012909759177 -4.739873792157624 24.86562424067748 0.9688589947434237 0.7450030758254003 0.2717281469721081 0.10979733748369212 2145.7948188997225 2474015.7464895546 0.026015629220278464 1.2274127450214694 1.8202297483428844e-05 4.739873792157624 -0.22385591891802348 DSFDDRGPSLNPVLDYDHGS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 DSFDDRGPSLNPVLDYDHGSR 21 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 1 DS(0.002)FDDRGPS(0.002)LNPVLDY(0.001)DHGS(0.995)R 64.035 0.002027 3908100.0 11016.0 11960.0 20503.0 22337.0 13889.0 16313.0 14589.0 20280.0 14003.0 14895.0 True False 14518.85885296571 15825.836109452714 20231.116823577773 17187.54975320982 11960.752091591099 15292.94553119238 15887.39273736212 17146.191988038947 14743.169992308915 14373.530583685158 1.0101108261769387 1.101040277982642 1.4075259175738866 1.1957778677368764 0.832137380718923 1.0639658393012232 1.1053229159574258 1.1929005116878473 1.0257166745826054 1.0 13.811126855398658 -8.74637034489084 0.17448763335917888 0.9518509470602012 1.1754302212707484 0.059692468183316194 0.1400607500886592 22.45657179129266 2.4318672394724077 1.6542875276481892 0.9447848416773859 1.7932038189756965e-09 8.74637034489084 0.22357927421054713 DSFDDRGPSLNPVLDYDHGSR ddPTM_PC-9_AZD4547_30min_R2 3 DSFDDRGPSLNPVLDYDHGSR 21 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 0 ;; 102.89 5.6911000000000004e-05 11995000.0 16128.699999999999 20582.5 103305.0 246483.0 142560.0 106594.0 42754.5 142047.0 61925.0 100920.0 False True 21257.291102199353 27235.390612275154 101935.10820171206 189660.15247438874 122768.00476472227 99928.66032930305 46559.56767355873 120096.90006533345 65198.22907760686 97386.8215176571 0.2182768753608538 0.27966197261440695 1.046703307625974 1.9474929925708857 1.2606223598997257 1.0261004391768254 0.4780889954922399 1.2331945759576803 0.669476917529194 1.0 16.571438938125425 -5.264756351239741 5.593784989747762 1.1069607433864426 0.23891870218676978 0.4510700654536063 0.3677646270281642 0.14325889356088514 17.68447099556074 0.10345072431862992 0.2480401745749916 5.435551923905401e-06 5.264756351239741 -0.8680420411996728 DSFSHS(ph)PGAVSSLK ddPTM_PC-9_AZD4547_30min_R2 1 DSFSHSPGAVSSLK 14 0 Q9H6R7;Q9H6R7-3 Q9H6R7 C2orf44 WD repeat and coiled-coil-containing protein C2orf44 1 DS(0.026)FS(0.047)HS(0.923)PGAVS(0.004)S(0.002)LK 57.196999999999996 0.038558999999999996 8565500.0 30437.0 16005.0 64663.0 121080.0 91941.0 62378.0 44448.0 85064.0 51660.0 70180.0 True False 40115.33287107094 21178.30325516645 63805.52636994636 93166.87666735219 79176.57916718103 58477.49379910002 48403.78589281451 71919.31337625963 54390.64213401976 67723.0195611295 0.5923441265766545 0.3127194178937941 0.9421541860275876 1.37570470529974 1.1691235813210172 0.8634803081442034 0.7147316555949387 1.061962591779334 0.8031337422119017 1.0 16.047358679551294 -5.317240962540879 6.697118693427642 1.0010066197658076 0.45365940290254364 0.5675265751205127 0.18815632868770818 0.15873809271291853 15.71874612280754 0.053389258643799876 0.11350403421460362 4.816804694418162e-06 5.317240962540879 -0.547347216863264 DSFSHS(ph)PGAVSSLK ddPTM_PC-9_Lapatinib_30min_R1 2 DSFSHSPGAVSSLK 14 0 Q9H6R7;Q9H6R7-3 Q9H6R7 C2orf44 WD repeat and coiled-coil-containing protein C2orf44 1 DS(0.045)FS(0.291)HS(0.663)PGAVS(0.001)SLK;DS(0.015)FS(0.049)HS(0.93)PGAVS(0.001)S(0.005)LK 63.185 0.025758 9981300.0 64149.0 48174.0 112123.0 49109.0 103352.0 114756.0 78488.0 77028.0 154454.0 71171.0 True False 63234.223496514125 48062.45606280175 102904.67974729635 52720.639682821544 97273.03855784998 109848.15338930165 82551.72459526661 80607.00208453924 137057.76404727527 83472.8125206037 0.7575427446020936 0.5757857512101732 1.2327927697643621 0.6315905513523753 1.1653259980168988 1.3159752268103784 0.9889654140369389 0.9656677383985705 1.6419449627798888 1.0 16.349018761224748 -5.513368148971858 0.5963471729989498 1.198871035561637 0.556732340844476 0.3198155748185125 0.2557514043117727 2.183373348638847 1.0551640487426786 0.1487073464220842 0.8672050491726513 3.0664214982049547e-06 5.513368148971858 -0.642138694717161 DSGALRVS(ph)GAASEPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSGALRVSGAASEPSK 16 1 O95873 O95873 C6orf47 Uncharacterized protein C6orf47 1 DS(0.137)GALRVS(0.863)GAASEPSK 51.166000000000004 0.042227999999999995 6022600.0 21917.0 26931.0 32120.0 29473.0 32348.0 32209.0 22857.0 22729.0 30580.0 26279.0 True False 25627.115219518244 29604.531699221458 32885.86261577836 27821.72336275522 26009.64161206097 30519.90333929606 20691.819489650443 22132.387833366152 31027.1746483238 31043.17467555046 0.8255313925641151 0.9536567058181045 1.05935887548509 0.8962267439955989 0.8378537918206577 0.9831437556975599 0.6665497232777315 0.7129550397046721 0.9994845879200859 1.0 14.921988483932427 -6.429523725346491 1.564826589400018 0.8378076340858676 0.9450767130152 0.04212402775699142 0.12128345075086408 0.8743001875590918 4.312333211876716 0.04795321537107962 0.0568804313316784 3.719429015041568e-07 6.429523725346491 0.10726907892933246 DSGFSSGNTDT(ph)SSER ddPTM_PC-9_Lapatinib_30min_R1 1 DSGFSSGNTDTSSER 15 0 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 DSGFSSGNT(0.001)DT(0.416)S(0.416)S(0.167)ER 102.64 0.0051325 0.0 19560.0 24491.0 24360.0 24193.0 27260.0 22707.0 26534.0 23808.0 23830.0 23295.0 True False 19281.07081313532 24434.292594222563 22357.214832319292 25972.233925482135 25656.62039522206 21735.874542602312 27907.8006881409 24914.206595377087 21146.0144589753 27321.509711363615 0.7057102999368992 0.894324393210958 0.8183008577677696 0.9506148891428102 0.9390630556755402 0.7955590584938242 1.0214589524140913 0.911889820825484 0.773969472491493 1.0 14.737749584733812 -4.087051636662498 1.3053876639099222 0.9046191971817779 5.5031002664172846e-17 0.3491705819562765 0.07931212623349015 8.20058657718982 3.3115295834609157 0.022289448846944927 15.409480831342195 8.183674802494378e-05 4.087051636662498 -0.9046191971817779 DSGGKT(ph)PGDFSYAYQKPEETTR ddPTM_PC-9_AZD4547_30min_R2 1 DSGGKTPGDFSYAYQKPEETTR 22 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DS(0.266)GGKT(0.696)PGDFS(0.02)Y(0.016)AY(0.002)QKPEETTR 64.843 0.019671 0.0 4729.3 4331.5 6652.7 5713.7 8120.7 9174.4 9827.9 17379.0 12388.0 8077.3 True False 6233.119024449053 5731.572667900872 6564.480851203038 4396.494740785022 6993.280978485414 8600.723317683529 10702.564060834955 14693.474879690772 13042.804389396752 7794.516185538775 0.799680041208126 0.7353339875712495 0.8421922150065155 0.5640497288262577 0.8972052673981358 1.1034326073554785 1.3730889520367542 1.8851041591204452 1.6733308493983456 1.0 12.928243760646572 -7.075091159170797 1.7923028081029897 1.5816113004170123 0.7487500601052299 0.6880125595031011 0.22661852472054933 0.18363015525027412 1.1736164564330853 0.10614577513671422 0.07645313518931522 8.412185498685109e-08 7.075091159170797 -0.8328612403117823 DSGGKT(ph)PGDFSYAYQKPEETTR ddPTM_PC-9_Lapatinib_30min_R1 1 DSGGKTPGDFSYAYQKPEETTR 22 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DS(0.272)GGKT(0.72)PGDFS(0.006)Y(0.002)AYQKPEETTR 71.434 0.013109 8165800.0 9086.9 10664.0 9722.0 10305.0 17473.0 15656.0 15867.0 10247.0 14823.0 17245.0 True False 8957.319139666626 10639.308163194204 8922.694688005262 11062.864076472266 16445.272493239725 14986.429375918524 16688.515622172737 10723.113028512646 13153.477646890082 20225.775272481886 0.4428665412817811 0.5260272113113746 0.4411546439035643 0.5469686045371922 0.8130849014037197 0.740956980586463 0.8251112947387607 0.5301706799393714 0.6503324332287032 1.0 14.303907383086209 -6.106117846764664 4.525747876590362 0.737910163481846 0.47772975387506145 0.5609480546244322 0.11757743723618336 0.18767648283021862 6.271238519218914 0.03519875547159168 0.0466164213058349 7.832170862464472e-07 6.106117846764664 -0.26018040960678457 DSGLES(ph)PAAAEAPLR ddPTM_PC-9_AZD4547_30min_R2 2 DSGLESPAAAEAPLR 15 0 H0YM15;J3KNL7;Q8NBR6-2;Q8NBR6 H0YM15 FAM63B Protein FAM63B 1 DS(0.064)GLES(0.936)PAAAEAPLR;DS(0.002)GLES(0.998)PAAAEAPLR 160.03 0.00027638 4846800.0 14347.599999999999 15630.400000000001 18904.2 22420.1 20201.9 23618.3 18506.6 28637.0 21707.0 17886.2 True False 18909.8383513808 20682.621130868727 18653.517956215142 17251.49233209202 17397.21489517707 22141.443967348816 20153.651547965288 24211.809662794447 22854.387704281202 17260.00958213557 1.0955867817682345 1.1982971986455686 1.080736245680992 0.9995065327163917 1.0079493184745103 1.2828175941608757 1.1676500787592081 1.4027691901083368 1.324123697355065 1.0 14.075145644998857 -6.770417965478803 24.988302069899117 1.2564063375720407 1.0791537865157155 0.325908042138093 0.11234262700107174 213.24292345119693 593472.7043280703 0.039477499144100495 0.03531131410029469 1.6966100471528686e-07 6.770417965478803 -0.1772525510563252 DSGLES(ph)PAAAEAPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DSGLESPAAAEAPLR 15 0 H0YM15;J3KNL7;Q8NBR6-2;Q8NBR6 H0YM15 FAM63B Protein FAM63B 1 DS(0.001)GLES(0.999)PAAAEAPLR;DSGLES(1)PAAAEAPLR 146.2 3.3134e-05 3822400.0 17708.300000000003 19560.6 20360.9 18485.1 22014.7 18506.199999999997 21507.0 16070.4 14926.4 16216.400000000001 True False 20705.965435132315 21502.447096498145 20846.38107514325 17449.439776502786 17701.07756884626 17535.70229369682 19469.701262804047 15648.569027996275 15144.670362025518 19156.30495104824 1.0808955844064947 1.1224736269048339 1.088225580476705 0.9108979952601948 0.9240340250418517 0.9154010827509436 1.0163599562941106 0.8168886989419104 0.790584113205861 1.0 14.225531686818961 -5.750782327015003 5.472821189564428 0.907492921084788 1.1020168854818497 0.6269955228451629 0.06597003642536711 0.11064857462646725 10.15021773213273 0.019163452787819127 0.03176607016471883 1.7750789462979964e-06 5.750782327015003 0.19452396439706177 DSGLES(ph)PAAAEAPLR ddPTM_PC-9_Lapatinib_30min_R1 2 DSGLESPAAAEAPLR 15 0 H0YM15;J3KNL7;Q8NBR6-2;Q8NBR6 H0YM15 FAM63B Protein FAM63B 1 DSGLES(1)PAAAEAPLR;DS(0.002)GLES(0.998)PAAAEAPLR 151.49 1.595e-05 3151900.0 9166.1 20338.9 16808.3 13609.2 21112.0 22218.0 18855.6 18653.3 21612.0 18266.7 True False 9035.389733143127 20291.806526668297 15426.386455914304 14610.065966960345 19870.233667789005 21267.787932687646 19831.85070684062 19520.00041521956 19177.82897555074 21424.074756152208 0.4217400207935932 0.9471497256067609 0.7200491331129439 0.6819461812587668 0.9274721963002395 0.9927050841054557 0.9256806155022234 0.9111245473793044 0.8951531953576465 1.0 14.38694527940487 -6.269378127279548 20.8911521171898 0.9392959956173642 0.7128466973358614 0.4953743218027893 0.12257758116977256 57.948748964416545 152494.27933393835 0.03623859009021564 0.042035278789928625 5.378013310000877e-07 6.269378127279548 -0.22644929828150284 DSGNWDTSGSELS(ph)EGELEKR ddPTM_PC-9_AZD4547_30min_R2 2 DSGNWDTSGSELSEGELEKR 20 1 O75400-2;O75400-3;O75400 O75400-2 PRPF40A Pre-mRNA-processing factor 40 homolog A 1 DSGNWDTS(0.002)GS(0.008)ELS(0.989)EGELEKR;DSGNWDT(0.001)S(0.001)GS(0.038)ELS(0.96)EGELEKR 60.388000000000005 0.0062770000000000005 10685900.0 15115.2 11169.1 16547.3 22279.3 16986.8 16853.2 14906.0 15775.8 14156.699999999999 14623.5 True False 19921.519184308956 14779.293151345193 16327.87199018625 17143.15159675372 14628.476033511397 15799.366739795963 16232.605123251737 13338.012601819755 14904.994260524132 14111.535716046983 1.4117187232609367 1.0473199691893822 1.1570584746222166 1.2148324563469959 1.036632463529577 1.1196064735767672 1.1503074824657653 0.9451850507420243 1.0562276537751214 1.0 13.784587380196456 DSGNWDTSGSELS(ph)EGELEKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSGNWDTSGSELSEGELEKR 20 1 O75400-2;O75400-3;O75400 O75400-2 PRPF40A Pre-mRNA-processing factor 40 homolog A 1 DSGNWDTS(0.001)GS(0.033)ELS(0.965)EGELEKR 58.913000000000004 0.0074923 3376100.0 4178.0 5918.3 5048.2 7480.4 6671.1 3626.7 6994.5 5811.5 4429.0 4346.5 True False 4885.252880738568 6505.829711317904 5168.568233405114 7061.297439784017 5363.945843892049 3436.5094675595346 6331.93032420527 5658.954282793234 4493.765746155204 5134.4860431249335 0.9514589853214056 1.2670848954841736 1.0066378971515204 1.3752686014677322 1.0446899258932376 0.6692996024716075 1.2332159968929532 1.1021462002746238 0.875212379274523 1.0 12.326004156114125 -6.512689693693798 24.94014871707867 0.9827208100044964 1.1559395360776392 0.17713680697788992 0.1765393876103343 862.0652555016763 2110117.1504932507 0.055901449306254576 0.059336349963884705 3.0712156086721876e-07 6.512689693693798 0.17321872607314281 DSGNWDTSGSELS(ph)EGELEKR ddPTM_PC-9_Lapatinib_30min_R1 1 DSGNWDTSGSELSEGELEKR 20 1 O75400-2;O75400-3;O75400 O75400-2 PRPF40A Pre-mRNA-processing factor 40 homolog A 1 DSGNWDT(0.001)S(0.008)GS(0.081)ELS(0.91)EGELEKR 52.465 0.016561000000000003 4573300.0 12171.0 8118.0 10636.0 8439.1 9065.2 7785.1 9169.7 7489.5 10092.0 7403.7 True False 11997.439308111962 8099.203269768438 9761.549136147294 9059.739566012331 8532.002758868926 7452.14942095448 9644.462198313311 7837.489511763979 8955.332686528684 8683.419680189862 1.3816491370885393 0.9327204682097492 1.1241595472365629 1.0433377516787534 0.9825625241094388 0.8582044511744179 1.1106755809944264 0.9025809877235617 1.0313140463496377 1.0 13.084047597385322 -4.7553204412992605 24.981432964746126 0.9993183337459297 1.381649770121797 0.6705858244606728 0.08058224288166282 118.34148839475853 483098.73966831464 0.019597222126937878 0.17549141491414152 1.7566270200951648e-05 4.7553204412992605 0.3823314363758672 DSGPLPT(ph)PPGVSLLGEPPKDYR ddPTM_PC-9_AZD4547_30min_R2 6 DSGPLPTPPGVSLLGEPPKDYR 22 1 A0A087WZ13;Q8IY67-2;E9PAU2 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 DS(0.041)GPLPT(0.958)PPGVS(0.001)LLGEPPKDYR;DS(0.066)GPLPT(0.933)PPGVS(0.001)LLGEPPKDYR;DS(0.014)GPLPT(0.986)PPGVSLLGEPPKDYR;DS(0.128)GPLPT(0.865)PPGVS(0.007)LLGEPPKDYR;DS(0.007)GPLPT(0.988)PPGVS(0.005)LLGEPPKDYR;DS(0.095)GPLPT(0.902)PPGVS(0.002)LLGEPPKDYR 103.74 0.00020962 33668900.0 112336.5 115027.3 138897.1 178915.1 141680.6 153044.3 113134.79999999999 146782.5 125095.7 126445.4 True False 148057.17025564512 152207.62524354944 137055.23370024713 137668.98790573978 122010.69427517342 143474.41572730104 123203.57802885157 124100.63735129806 131708.00331406685 122018.58503298467 1.2133985180669122 1.2474134592070865 1.1232324458048557 1.1282624517283528 0.9999353315086458 1.1758406777829484 1.0097115779169752 1.017063403232799 1.0794093643887355 1.0 16.89674138036323 -5.134165005460836 0.5199742830150628 1.0315904025964633 1.3435775311902993 0.6284269286192187 0.05353949290602773 1.9984587508367468 0.5385435473553146 0.03364601015017566 0.3632800863879443 7.342348506167405e-06 5.134165005460836 0.31198712859383604 DSGPLPT(ph)PPGVSLLGEPPKDYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DSGPLPTPPGVSLLGEPPKDYR 22 1 A0A087WZ13;Q8IY67-2;E9PAU2 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 DS(0.192)GPLPT(0.808)PPGVSLLGEPPKDYR;DS(0.039)GPLPT(0.957)PPGVS(0.004)LLGEPPKDYR;DS(0.204)GPLPT(0.793)PPGVS(0.003)LLGEPPKDYR 91.175 0.00014393 21878000.0 43444.3 43318.3 45314.4 46383.0 59427.1 55402.0 76520.6 53872.3 51242.7 42645.2 True False 50798.561925962334 47618.6545433287 46394.86715181902 43784.31088571494 47782.78635600681 52496.62159035303 69272.01480683152 52458.209207420055 51992.02754583591 50376.43718078254 1.008379408485458 0.9452564970492621 0.9209636438822554 0.8691426654209214 0.9485146038520337 1.042086827259378 1.3750876140414554 1.0413243203199702 1.0320703577995325 1.0 15.620461472177876 -6.898358848369373 4.285515566405311 1.1264521238815666 0.9346471357353704 0.38364076377369816 0.10264640642977775 0.2154505551413517 7.111230595411675 0.0380622734841777 0.03333397255117365 1.2636917541277852e-07 6.898358848369373 -0.19180498814619618 DSGPLPT(ph)PPGVSLLGEPPKDYR ddPTM_PC-9_Lapatinib_30min_R1 3 DSGPLPTPPGVSLLGEPPKDYR 22 1 A0A087WZ13;Q8IY67-2;E9PAU2 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 DS(0.037)GPLPT(0.932)PPGVS(0.031)LLGEPPKDYR;DS(0.027)GPLPT(0.973)PPGVSLLGEPPKDYR;DS(0.013)GPLPT(0.987)PPGVS(0.001)LLGEPPKDYR 94.176 0.00013108 23823700.0 110408.0 97709.0 110963.0 99952.0 104384.0 138066.0 137725.0 129342.0 150986.0 116520.0 True False 108833.56167365256 97482.76081372284 101840.05046956685 107302.80351009748 98244.33834684009 132161.2390275657 144855.72660639955 135351.7015061855 133980.3667269344 136660.32674685906 0.7963800779962201 0.7133215845026752 0.745205670832391 0.7851788888874706 0.7188943615568963 0.9670783187308838 1.0599691223826877 0.9904242491451262 0.980389626721083 1.0 17.0602349557657 -6.824075659919307 5.1752497644413005 1.0068413338006457 0.7510550970901292 0.9380376349921794 0.03191127145514021 0.044110415127406925 2.3106218788011 0.011127340360409655 0.00992281668418269 1.4994235930613797e-07 6.824075659919307 -0.2557862367105165 DSGRLS(ph)PDLSVCGQPR ddPTM_PC-9_AZD4547_30min_R2 1 DSGRLSPDLSVCGQPR 16 1 Q8TF76-2;Q8TF76 Q8TF76-2 GSG2 Serine/threonine-protein kinase haspin 1 DS(0.425)GRLS(0.569)PDLS(0.006)VCGQPR 83.25200000000001 0.027385000000000003 7171600.0 17237.0 16651.0 18875.0 25711.0 18022.0 23542.0 14514.0 22211.0 17064.0 21040.0 True False 22718.00744812729 22033.110121947946 18624.705167294083 19783.726180990187 15519.956382364096 22069.915018410542 15805.717882656358 18778.800308004596 17965.968203153567 20303.39600407757 1.1189264812430781 1.0851933399478093 0.917319701765835 0.9744047831711001 0.7644019935998486 1.0870060857788617 0.7784765602504164 0.9249093257223182 0.8848750327061259 1.0 14.309433436441429 -5.221684040074989 2.7672506090232005 0.9091916493134874 1.1194478799313308 0.398412793077751 0.09123330318408213 0.25715699002416614 3.8077443109410356 0.022935104974741792 0.07656713175209709 6.002275977971598e-06 5.221684040074989 0.21025623061784338 DSGRLS(ph)PDLSVCGQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSGRLSPDLSVCGQPR 16 1 Q8TF76-2;Q8TF76 Q8TF76-2 GSG2 Serine/threonine-protein kinase haspin 1 DS(0.236)GRLS(0.753)PDLS(0.012)VCGQPR 127.2 0.00012272 6854800.0 14191.0 13969.0 16769.0 15155.0 24965.0 14402.0 15001.0 13897.0 14718.0 10898.0 True False 16593.256014973926 15355.750002095161 17168.83655678665 14305.914483172926 20073.28746275201 13646.733766727995 13579.996682165032 13532.21847508862 14933.222906279596 12873.721131479473 1.2889246120454838 1.192798091963209 1.3336343378453759 1.1112493689327618 1.559245167558259 1.0600457806529857 1.0548618028518995 1.0511505055052774 1.1599771933667358 1.0 13.652141502415326 DSGRLS(ph)PDLSVCGQPR ddPTM_PC-9_Lapatinib_30min_R1 2 DSGRLSPDLSVCGQPR 16 1 Q8TF76-2;Q8TF76 Q8TF76-2 GSG2 Serine/threonine-protein kinase haspin 1 DS(0.442)GRLS(0.558)PDLSVCGQPR;DS(0.35)GRLS(0.65)PDLSVCGQPR 109.13 0.0003387 27967000.0 29464.0 28922.0 33227.0 32068.0 34390.0 28053.0 32099.0 24688.0 34620.0 23502.0 True False 29043.837956964155 28855.032885962373 30495.20431992913 34426.387695712016 32367.247813341386 26853.23858473699 33760.929158386774 25835.09460797503 30720.731035238136 27564.289385553468 1.0536762820443368 1.0468266561257837 1.106330146711918 1.2489488560425213 1.174245682905403 0.974203913227339 1.2248068029673562 0.9372668472097555 1.1145119906968821 1.0 14.750512788409896 -7.770874190153808 24.9999746058402 1.01941710794769 1.1168334776977624 0.21597006030328814 0.08827283946836344 341.2106505177252 904111.4784128522 0.04775613597413369 0.02341894467847692 1.69482870066712e-08 7.770874190153808 0.0974163697500725 DSGS(ph)DQDLDGAGVR ddPTM_PC-9_AZD4547_30min_R2 1 DSGSDQDLDGAGVR 14 0 E7ERS3;Q86VM9;H3BPD0 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 DS(0.012)GS(0.988)DQDLDGAGVR 126.91 3.0415999999999998e-05 5463800.0 12953.0 17389.0 13692.0 14358.0 18243.0 12482.0 14647.0 13655.0 13105.0 13460.0 True False 17071.78456086284 23009.65418957134 13510.435133806135 11047.984928888696 15710.27434710178 11701.498566808277 15950.554625001232 11544.933510684019 13797.703545612254 12988.769496905152 1.3143496437388125 1.7715037744763948 1.040162821969031 0.8505797975336394 1.2095275346017254 0.9008935426559387 1.2280266139761575 0.8888396636367165 1.0622794983697146 1.0 13.664977141759445 -5.280178902954957 23.85346568307037 1.0220997750756677 1.5429266337839318 0.6375468894780371 0.1569482051867108 216.54984827963838 275645.44411585917 0.03768309292808198 0.07870051947597397 5.245913159661566e-06 5.280178902954957 0.5208268587082641 DSGS(ph)DQDLDGAGVR ddPTM_PC-9_Lapatinib_30min_R1 1 DSGSDQDLDGAGVR 14 0 E7ERS3;Q86VM9;H3BPD0 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 DS(0.194)GS(0.806)DQDLDGAGVR 85.976 0.0066827 4128500.0 21160.0 24467.0 11331.0 13275.0 12155.0 12742.0 14275.0 12645.0 12872.0 10968.0 True False 20858.254519731243 24410.348164747993 10399.408918924873 14251.28778410182 11440.066797649457 12197.054363052748 15014.08965188856 13232.532862842041 11422.219811830879 12863.804186058653 1.6214685965397935 1.8975994823679831 0.808424068689991 1.1078595085850944 0.8893222123240812 0.948168534489315 1.1671578200918444 1.0286640461445304 0.8879348322333673 1.0 13.65102973051722 -5.259585659009352 24.999997582923708 0.9876344635198464 1.7595340936602986 0.8742229671176248 0.11828886042521826 47.17203132836585 636167.6343837591 0.02941351640630892 0.07011238607739667 5.500654164710852e-06 5.259585659009352 0.7718996301404522 DSGS(ph)ISLQETR ddPTM_PC-9_AZD4547_30min_R2 2 DSGSISLQETR 11 0 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 DS(0.001)GS(0.999)ISLQETR;DS(0.006)GS(0.785)IS(0.206)LQET(0.003)R 197.36 9.8811e-05 71609000.0 34953.0 54295.0 74216.0 89979.0 84775.0 100450.0 86410.0 110943.0 93008.0 88879.0 True False 46067.3269324356 71844.79695340595 73231.84734812702 69235.73171169209 73005.45457301718 94168.84562056478 94100.322601649 93799.30856651915 97924.21300040459 85767.3732626622 0.5371194800539667 0.8376704826132612 0.8538427208660666 0.807250229054561 0.8512031066806524 1.0979565076823925 1.0971575672892206 1.0936479106018462 1.1417420083568623 1.0 16.388141316504502 -5.581376366151812 0.48908173731777604 1.1181662672291093 0.5111797372207725 0.7752365640758581 0.08515092891686322 1.1092619576004334 0.3560466457730821 0.06639244278689167 0.3582015017053945 2.621945341131488e-06 5.581376366151812 -0.6069865300083368 DSGS(ph)ISLQETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DSGSISLQETR 11 0 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 DS(0.115)GS(0.884)IS(0.001)LQETR;DS(0.429)GS(0.565)IS(0.006)LQETR 129.76 0.00024321 74801000.0 82045.0 108034.0 129187.0 73418.0 132664.0 94124.0 86379.0 72022.0 69068.0 73074.0 True False 95933.5980373855 118758.90154816706 132267.3080244257 69304.62748436762 106669.4415364922 89187.97174416776 78196.55579019638 70131.49881361666 70077.98883618134 86321.73774653407 1.111349244602497 1.3757705144546328 1.5322595614652859 0.8028641370481481 1.2357193485805968 1.0332040812946768 0.9058732809550752 0.8124430837982353 0.8118231938512505 1.0 16.397436287622277 -6.493116269217798 0.7979828401161478 0.8579586985705302 1.3132447994205683 0.434000333486508 0.18013175453176428 0.5962607312259044 0.841554660842207 0.10998822963643398 0.1424017556799453 3.2128002933449974e-07 6.493116269217798 0.45528610085003807 DSGS(ph)ISLQETR ddPTM_PC-9_Lapatinib_30min_R1 3 DSGSISLQETR 11 0 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 DS(0.001)GS(0.999)ISLQETR;DS(0.012)GS(0.988)ISLQETR;DS(0.004)GS(0.974)IS(0.022)LQETR 127.78 0.0003432 117744000.0 159424.0 213098.0 428808.0 199546.0 302145.0 301347.0 220003.0 202658.0 410426.0 204275.0 True False 157150.58452521916 212604.58467370193 393553.06148674834 214221.27850594217 284373.42513992515 288459.0912841671 231393.67885705346 212074.23051940228 364199.50190261786 239583.66157067235 0.6559319758908639 0.8873918333157617 1.6426540061483204 0.8941397635445655 1.1869483222504333 1.2040015140977276 0.9658157711593242 0.8851781842262422 1.5201349687828623 1.0 17.870170001200094 -5.007605715976525 24.086531321784364 1.1520915673646488 0.7137964715644591 0.3154703252281793 0.24061957355854682 248.3306743150732 786471.9843979066 0.057948936627040655 0.19168461512163826 9.826396497107218e-06 5.007605715976525 -0.43829509580018966 DSGS(ph)QEVLSELR ddPTM_PC-9_AZD4547_30min_R2 2 DSGSQEVLSELR 12 0 Q9BVJ6-3;Q9BVJ6;Q9BVJ6-2;X6RJY0 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 1 DS(0.14)GS(0.86)QEVLSELR;DS(0.014)GS(0.986)QEVLSELR 136.83 6.4567e-05 10835100.0 23647.0 24186.0 32032.0 36004.0 35379.0 33632.0 30047.0 35063.0 32494.0 32454.0 True False 31166.254111844613 32003.651516991933 31607.23475066299 27703.834056254953 30467.236535992615 31528.985723353282 32721.12479124817 29644.819017584312 34211.566502184214 31317.795338228803 0.9951611783413372 1.0218998869925535 1.0092420111092837 0.8846035858225824 0.9728410383601321 1.006743462713248 1.0448093308568998 0.9465806483956956 1.0924002195142728 1.0 14.93469503513642 -6.857073914788502 4.786829457296473 1.017529231533025 0.9760364496736215 0.1557795420736674 0.04863734053880068 0.4562480839218301 17.738654596394596 0.017844507020206755 0.015795385952068784 1.3897160882297702e-07 6.857073914788502 -0.04149278185940364 DSGS(ph)QEVLSELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSGSQEVLSELR 12 0 Q9BVJ6-3;Q9BVJ6;Q9BVJ6-2;X6RJY0 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 1 DS(0.032)GS(0.968)QEVLSELR 134.37 5.7195e-05 4143500.0 5671.7 3530.7 5914.8 4942.5 7382.8 6001.5 6254.1 5176.7 4779.1 4844.2 True False 6631.806788818798 3881.204562416591 6055.831264003913 4665.587748801201 5936.193337873243 5686.770774963063 5661.666372237071 5040.817110167036 4848.985296331076 5722.415113333902 1.1589174601062944 0.6782458954040099 1.0582649360570002 0.8153179481736359 1.0373580420688482 0.9937711022942423 0.9893840730017508 0.8808898009550788 0.8473669246805197 1.0 12.482408441572705 -4.427318092686874 20.744830933131983 0.9268805985583607 23.441367586380732 0.28508570213046236 0.11220409921224038 333.14964262562245 72284.65806900933 0.025491464339950753 184.01083946006318 3.738366767276504e-05 4.427318092686874 22.514486987822373 DSGS(ph)QEVLSELR ddPTM_PC-9_Lapatinib_30min_R1 2 DSGSQEVLSELR 12 0 Q9BVJ6-3;Q9BVJ6;Q9BVJ6-2;X6RJY0 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 1 DS(0.009)GS(0.991)QEVLSELR;DS(0.001)GS(0.999)QEVLSELR 157.37 0.00011776 11061800.0 18976.1 22029.5 24592.4 21917.3 23429.0 18458.0 18494.2 18835.4 21022.3 17194.1 True False 18705.497334209453 21978.49204623844 22570.507801409254 23529.171355969476 22050.95228318627 17668.59436769955 19451.739183184407 19710.5614460083 18654.54719936703 20166.077275301886 0.9275724316061579 1.0898744334951191 1.1192314446326237 1.166769869754813 1.0934676081100243 0.8761542528322505 0.964577241157736 0.9774117780530638 0.9250459047984467 1.0 14.299642856368006 -6.743580414185384 24.98488389868188 0.9482222879130272 1.0870346602840433 0.5002289793646028 0.06511788393456988 202.2387319361761 282933.53307947307 0.022212610876865435 0.022167605445113404 1.8047605358207113e-07 6.743580414185384 0.13881237237101607 DSGSDGHS(ph)VSSR ddPTM_PC-9_AZD4547_30min_R2 2 DSGSDGHSVSSR 12 0 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 DSGSDGHS(0.778)VS(0.053)S(0.169)R;DSGSDGHS(0.909)VS(0.053)S(0.038)R 93.649 0.0052028 663730.0 1772.13 1874.08 9165.2 13062.8 10596.6 9630.6 4293.9800000000005 10304.6 9285.0 10347.6 True False 2335.630477406149 2479.839710368156 9043.663459564701 10051.37327824817 9125.445000630301 9028.397059566076 4676.135901458507 8712.260846151192 9775.786144296811 9985.33367356432 0.2339061020654338 0.24834820662362134 0.905694667320668 1.0066136602784428 0.9138848333921447 0.9041657850121035 0.4683004148212239 0.8725057300004379 0.9790144690084542 1.0 13.28559492276231 -5.258929376062387 24.581162195067392 0.8684289076401923 0.24112705743572577 0.7539072888125335 0.1461475202471883 84.81515887482449 830602.0574707937 0.040248940042796125 0.0966888288082823 5.5089727472866135e-06 5.258929376062387 -0.6273018502044665 DSGSDGHSVSS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSGSDGHSVSSR 12 0 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 DSGSDGHS(0.085)VS(0.42)S(0.496)R 105.66 0.0017644000000000002 453600.0 587.84 956.69 3184.9 3426.6 4858.5 5204.2 2901.5 893.29 3678.2 2957.3 True False 687.3497016307708 1051.6638606560534 3260.8400948005137 3234.61871118709 3906.5118020340715 4931.282590529495 2626.6489149591243 869.842084018991 3731.986716529255 3493.435080026081 0.19675468010289726 0.3010400469924296 0.9334194052852327 0.9259135026384808 1.1182437092848185 1.4115855819747134 0.7518814160815934 0.24899334439971818 1.0682856933186213 1.0 11.770430614972188 -5.23270763282992 4.690734675816164 0.9242906180840873 0.22820407496171138 0.48673802301348956 0.2811031915538811 0.18090350036592934 10.345121031729901 0.08010877172256509 0.21424509827207183 5.851838975400312e-06 5.23270763282992 -0.696086543122376 DSGSDGHSVSS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 DSGSDGHSVSSR 12 0 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 DSGS(0.001)DGHS(0.011)VS(0.064)S(0.925)R 84.352 0.037832 0.0 741.87 2157.8 3208.7 977.34 3034.2 3226.3 2320.7 3457.7 6572.2 2872.3 True False 731.2907977577037 2152.803746674838 2944.8930719401847 1049.2168439106642 2855.734321466719 3088.318669872632 2440.854490727692 3618.3573649544414 5831.969627665857 3368.7732279008255 0.21707925950640225 0.6390467986520745 0.8741737340910976 0.31145368741975543 0.8477074971431677 0.9167487571720724 0.7245529234535787 1.0740875446843712 1.7311849843035936 1.0 11.718007600033516 -7.454092580589163 0.9245581155074598 1.3351325977971664 0.5655038737056546 0.529305381218808 0.27463601981705665 0.47224569984111536 0.7542332776253778 0.22453049131351163 0.11239121314455677 3.514855047297949e-08 7.454092580589163 -0.7696287240915118 DSGSDQDLDGAGVRAS(ph)DLEDEESAAR ddPTM_PC-9_AZD4547_30min_R2 2 DSGSDQDLDGAGVRASDLEDEESAAR 26 1 E7ERS3;Q86VM9;H3BPD0 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 DSGSDQDLDGAGVRAS(0.998)DLEDEES(0.002)AAR;DSGSDQDLDGAGVRAS(1)DLEDEESAAR 71.426 9.8862e-05 48087000.0 45874.0 45945.0 52291.0 56031.0 68954.0 59781.0 46953.0 70367.0 55194.0 58269.0 True False 60460.97776152407 60795.822746555605 51597.58717366754 43113.918620320524 59380.927332678635 56042.884619641496 51131.7260399865 59493.39702279763 58111.442159215774 56229.02004570324 1.0752628751555882 1.0812178959750756 0.9176326945006111 0.7667556465554141 1.0560548144786004 0.9966896910899309 0.9093476286520086 1.0580550216674787 1.033477768454483 1.0 15.779027283488032 -7.784502789181019 24.99498318880958 1.0343248048815161 0.9702782262381543 0.08123786341145 0.09001786111771615 671.8763921990625 728135.888766625 0.05273733849301557 0.0253591903798366 1.6424691111676454e-08 7.784502789181019 -0.06404657864336183 DSGSDQDLDGAGVRAS(ph)DLEDEESAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DSGSDQDLDGAGVRASDLEDEESAAR 26 1 E7ERS3;Q86VM9;H3BPD0 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 DS(0.001)GS(0.011)DQDLDGAGVRAS(0.976)DLEDEES(0.011)AAR;DSGSDQDLDGAGVRAS(0.999)DLEDEES(0.001)AAR 79.82 1.8042e-05 23229300.0 48818.0 42010.0 48648.0 53799.0 54506.0 43452.0 59042.0 47646.0 51855.0 43773.0 True False 57081.92320054945 46180.47516558219 49807.95281856742 50784.816448711324 43825.94057459486 41173.30062712574 53449.114332936966 46395.34298510994 52613.28127497812 51708.69839312263 1.103913364180551 0.8930891049410807 0.9632412798306288 0.9821329491338698 0.8475545108755591 0.7962548257181017 1.0336580883661504 0.8972444564816319 1.017493824249419 1.0 15.658119369433193 -10.845357660594356 14.701660807831596 0.9999999990590887 0.941674169426377 0.025488703378085953 0.08773430022275001 0.0 0.0 0.08363902379744777 0.02028544306528105 1.4277176859547703e-11 10.845357660594356 -0.0583258296327116 DSGSDQDLDGAGVRAS(ph)DLEDEESAAR ddPTM_PC-9_Lapatinib_30min_R1 1 DSGSDQDLDGAGVRASDLEDEESAAR 26 1 E7ERS3;Q86VM9;H3BPD0 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 DSGSDQDLDGAGVRAS(0.996)DLEDEES(0.004)AAR 87.704 4.4383e-07 24940000.0 30994.0 47473.0 47046.0 43464.0 45003.0 47972.0 38887.0 44274.0 58246.0 43825.0 True False 30552.0198763965 47363.079185232426 43178.05948281174 46660.487551653605 42356.01201930221 45920.34938819388 40900.37858444769 46331.13167018334 51685.72212242862 51400.09285685814 0.5943962000512233 0.9214590198724307 0.8400385501842657 0.9077899466367959 0.8240454377632664 0.8933903974857681 0.7957257722928509 0.9013822562385029 1.0055569795635568 1.0 15.649483345272255 -1.5228787895186362 0.1707676013753489 0.9899363207622275 1.22016431893581e-09 0.44924429870005667 0.08308569191459138 66.93868549826848 0.7268692891798922 0.2140812460330306 16.945476809945667 0.029999996944126747 1.5228787895186362 -0.9899363195420632 DSGSDTASAIIPSTTPS(ph)VDSDDESVVKDK ddPTM_PC-9_Lapatinib_30min_R1 1 DSGSDTASAIIPSTTPSVDSDDESVVKDK 29 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 DS(0.001)GS(0.001)DT(0.001)AS(0.001)AIIPS(0.057)T(0.057)T(0.057)PS(0.408)VDS(0.408)DDES(0.009)VVKDK 40.997 0.032159 5474900.0 12661.0 15989.0 12468.0 16327.0 15572.0 12338.0 13607.0 14548.0 15691.0 15242.0 True False 12480.451818256966 15951.978452861236 11442.929167871798 17527.742045275372 14656.085575729923 11810.332501282757 14311.503880437665 15223.953190085105 13923.714346444864 17876.55939131163 0.6981461893793006 0.8923405283800987 0.6401080273552691 0.9804874451285188 0.8198493487988006 0.6606602670434903 0.8005737327392733 0.8516153951573172 0.778881105791088 1.0 14.125781474754392 -10.871631800686577 0.5674164938042259 1.088911354058786 0.791724376387219 0.2827652822136374 0.09965268808309159 57.073546133538855 8.395725255064054 7.758206059116739 0.040928746176541436 1.3439038537499081e-11 10.871631800686577 -0.297186977671567 DSGSDTASAIIPSTTPSVDS(ph)DDESVVKDK ddPTM_PC-9_AZD4547_30min_R2 1 DSGSDTASAIIPSTTPSVDSDDESVVKDK 29 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 DSGSDTASAIIPS(0.249)T(0.073)T(0.073)PS(0.062)VDS(0.542)DDESVVKDK 65.278 0.0028239000000000003 0.0 19307.0 17238.0 16890.0 20800.0 18710.0 19992.0 19907.0 19787.0 22223.0 20472.0 True False 25446.22438945252 22809.846392537303 16666.02756427004 16004.881356796537 16112.439458108534 18741.89707960512 21678.684435031028 16729.373810025958 23397.6624108463 19755.281511191843 1.2880719707809085 1.1546201647197474 0.8436238964667921 0.8101570887627891 0.8156016126108073 0.948703113594579 1.0973614535813894 0.8468304438257873 1.1843750440909162 1.0 14.269950784301212 -5.06804146409039 4.082850927217448 0.9350424983373357 1.2664803707919579 0.48200615393390134 0.11846822748673329 0.17348327359420496 5.512111303045056 0.0313227467572686 0.10361970121187605 8.549850796323655e-06 5.06804146409039 0.3314378724546222 DSGSS(ph)SPLPK ddPTM_PC-9_AZD4547_30min_R2 2 DSGSSSPLPK 10 0 Q86VQ1;H7C0B2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 DS(0.003)GS(0.007)S(0.495)S(0.495)PLPK;DSGS(0.005)S(0.497)S(0.497)PLPK 104.43 0.0026051 16412900.0 122537.0 142367.0 152410.0 148170.0 163380.0 172828.0 184698.0 197791.0 194903.0 167105.0 True False 161501.2170720645 188384.34861157642 150388.94381707514 114011.6957036801 140697.50714408176 162021.03783883541 201135.7641925638 167226.94573502 205205.17467763938 161254.7048128035 1.0015287135934865 1.1682409442271282 0.9326174017164822 0.7070286466124097 0.8725172224116743 1.0047523142157093 1.247317183247814 1.0370360723995589 1.272553101107077 1.0 17.298981728064675 -7.048516263134065 6.36466165120432 1.1413182090947749 0.9362863138430634 0.34526570032383286 0.1319305823527545 0.2744577792390504 27.254320413372877 0.05403133250716383 0.04239168170634845 8.943010421907542e-08 7.048516263134065 -0.2050318952517115 DSGSS(ph)SPLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DSGSSSPLPK 10 0 Q86VQ1;H7C0B2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 DS(0.032)GS(0.165)S(0.401)S(0.401)PLPK;DSGS(0.003)S(0.499)S(0.499)PLPK 84.68700000000001 0.014033000000000002 5987500.0 107551.0 154423.0 112268.0 134817.0 134596.0 103877.0 119941.0 99062.0 92782.0 93496.0 True False 125757.2600709226 169753.09489394678 114944.89489876111 127263.64057261134 108222.88000547055 98429.50725499273 108579.32018235825 96461.72746486489 94138.76122370122 110446.08468607142 1.138630313861928 1.5369770270847336 1.040733089140072 1.1522693713800867 0.9798706791017532 0.8911996068920484 0.983097956717803 0.8733829518632983 0.8523503706924366 1.0 16.75298275049434 -5.851829945222423 1.10901149834876 0.9129466933919598 1.331594139526258 0.6012672808228015 0.12025029250378776 0.33640399174184543 0.819907977423448 0.0432030728590855 0.10625993196171216 1.4065981917706953e-06 5.851829945222423 0.4186474461342983 DSGSS(ph)SPLPK ddPTM_PC-9_Lapatinib_30min_R1 1 DSGSSSPLPK 10 0 Q86VQ1;H7C0B2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 DS(0.007)GS(0.045)S(0.474)S(0.474)PLPK 106.4 0.0023218 7105000.0 48570.0 89339.0 83790.0 86682.0 101540.0 108080.0 86697.0 99602.0 69611.0 81361.0 True False 47877.38289335287 89132.14103447161 76901.10963875345 93056.88344267507 95567.61683532095 103457.67034678554 91185.74644832095 104229.87253497775 61770.67614367306 95424.14044328219 0.5017323988557176 0.9340628128314094 0.8058873706539869 0.9751922627795201 1.0015035649404045 1.0841876056329613 0.9555836293072985 1.0922799204770357 0.6473275615239947 1.0 16.542066665613817 -4.4840021880903205 1.713038982685249 0.9603908302356499 6.39310917662882e-21 0.515645596520825 0.12688944049607956 1.8688165883313685 2.8525569240638347 0.03359438479930023 3.770189274281745 3.280936400865288e-05 4.4840021880903205 -0.9603908302356499 DSGYIDCWDSER ddPTM_PC-9_AZD4547_30min_R2 2 DSGYIDCWDSER 12 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 0 ; 102.53 0.009214 0.0 24376.0 22512.0 24565.0 37365.0 33717.0 28784.0 20057.1 34247.0 27091.0 31722.0 False True 32127.060947702637 29788.56375384615 24239.252049514136 28751.07653349535 29035.976547784394 26984.131929739582 21842.143044248805 28954.913067769707 28522.97495262733 30611.422435425342 1.049512188317107 0.9731192275264239 0.7918368413178685 0.9392270677439317 0.9485340515957942 0.8815053265382387 0.7135291765786026 0.9458859067673175 0.9317755492348132 1.0 14.901782464363864 -6.7734297685012 22.447007912516053 0.8798438746381594 0.9339372800897503 0.044956673356979615 0.0919160766647158 199.76702005712917 373973.5005637414 0.03343888082153286 0.02978240049195853 1.6848848742204233e-07 6.7734297685012 0.054093405451590915 DSGYIDCWDSER ddPTM_PC-9_Lapatinib_30min_R1 1 DSGYIDCWDSER 12 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 0 100.69 0.013616999999999999 1880900.0 10502.0 11496.0 12040.0 10409.0 11039.0 11252.0 11056.0 10903.0 12450.0 10407.0 False True 10352.239554169073 11469.381718312132 11050.117675744026 11174.512583406091 10389.707723509035 10770.778189693105 11628.42558257653 11409.59318335839 11047.74989568788 12205.836083544156 0.8481385038527518 0.9396637509965492 0.9053142775398841 0.915505706198325 0.8512081968326924 0.882428546145578 0.9526939001133984 0.9347653946246864 0.905120290004746 1.0 13.575283500745531 -9.630800240263271 0.34914089766186596 1.0227731101795223 0.8918533253812595 0.48151970329141225 0.031726808564759415 5.191117498604549 0.8274262735594344 0.19413625801327658 0.02948692481482589 2.3399132665524175e-10 9.630800240263271 -0.13091978479826283 DSGYIDCWDSERSDSLS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 2 DSGYIDCWDSERSDSLSPPR 20 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 DSGYIDCWDS(0.001)ERS(0.006)DS(0.066)LS(0.927)PPR;DSGY(0.001)IDCWDS(0.024)ERS(0.028)DS(0.314)LS(0.633)PPR 58.516000000000005 0.0080485 19966000.0 17372.3 14581.0 19567.0 45872.0 33013.8 22207.2 16356.7 16585.2 18232.6 19404.3 True False 22896.330033712446 19294.023103004183 19307.528795149312 35296.919115335164 28430.40372966882 20818.5802734197 17812.414612873465 14022.33842998143 19196.338013409368 18724.961363209255 1.2227704821169394 1.030390542803096 1.031111809559441 1.8850195966057606 1.5183157485990217 1.1118089842537127 0.9512657605730093 0.748858070144405 1.0251737048241003 1.0 14.192675121402292 -7.040183962126448 3.666989572363751 0.9151544334421924 1.3337886511290142 0.38279129741111884 0.24208713572925977 0.2779775705349077 7.746643693198675 0.1060744197700837 0.08425922808233602 9.116246039062656e-08 7.040183962126448 0.41863421768682185 DSIS(ph)SDSETSEPLSCR ddPTM_PC-9_AZD4547_30min_R2 1 DSISSDSETSEPLSCR 16 0 O75164 O75164 KDM4A Lysine-specific demethylase 4A 1 DS(0.026)IS(0.883)S(0.084)DS(0.004)ET(0.001)S(0.001)EPLS(0.001)CR 115.12 0.0001817 17013000.0 46936.0 46820.0 70866.0 87886.0 90747.0 55651.0 52893.0 65385.0 54991.0 72818.0 True False 61860.67167055182 61953.64938499806 69926.27053697812 67625.2405251645 78148.34545724103 52171.134172524195 57600.37453268177 55281.250647826724 57897.71199364842 70268.66398407414 0.8803450665373697 0.881668241181295 0.9951273664862388 0.9623811908604274 1.1121364919497083 0.7424523424032707 0.8197163752214851 0.7867127039779183 0.823947812737275 1.0 16.100593848455958 -6.780498575760642 24.999703641158668 0.8203073130408477 0.9630084977390941 0.3571035256052436 0.08730051561109681 256.3500590084809 336248.91147313133 0.03050888896922111 0.026948202596097502 1.6576827730984185e-07 6.780498575760642 0.14270118469824644 DSIS(ph)SDSETSEPLSCR ddPTM_PC-9_Lapatinib_30min_R1 1 DSISSDSETSEPLSCR 16 0 O75164 O75164 KDM4A Lysine-specific demethylase 4A 1 DSIS(0.498)S(0.498)DS(0.003)ET(0.001)SEPLSCR 160.79 5.6818000000000004e-05 24302000.0 40734.0 28800.0 35129.0 31271.0 28350.0 38504.0 28122.0 28684.0 28235.0 26753.0 True False 40153.12569029927 28733.315369466734 32240.829221861448 33570.77365699796 26682.508738244505 36857.27367720792 29578.01955799722 30016.76335609025 25054.876972268874 31377.220403868258 1.2796903350096969 0.9157380736607384 1.027523432824111 1.0699091004523549 0.8503783443786188 1.1746506925343863 0.9426590111325085 0.9566418876411918 0.7985053057529612 1.0 14.937429934303823 -4.754462122605765 24.999535742471128 0.9759306212098984 1.2796908575600252 0.45197433764661 0.10193533045493505 227.21166481901287 814029.020257961 0.02469046587649228 0.2402768609150038 1.760102166043015e-05 4.754462122605765 0.30376023635012683 DSISAVS(ph)SEK ddPTM_PC-9_Lapatinib_30min_R1 1 DSISAVSSEK 10 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DSIS(0.001)AVS(0.933)S(0.066)EK 82.774 0.036616 0.0 12336.0 19785.0 15944.0 15527.0 18062.0 16885.0 17408.0 23643.0 15752.0 16120.0 True False 12160.086377854668 19739.18904808678 14633.145865619817 16668.907376553587 16999.628671258277 16162.867910857449 18309.301062001825 24741.540093014984 13977.843884086384 18906.32052145016 0.6431757233808898 1.0440523858511597 0.7739816877122011 0.8816579279739747 0.8991505593048289 0.8548923040059472 0.9684222290227764 1.308638561635749 0.7393212163216965 1.0 14.206580998153322 -7.398466743892866 4.621741106406427 1.0379995257678565 0.8593667495514006 0.17937175179881282 0.15979660683202385 0.3516558005604544 11.667282138459655 0.06514794020594829 0.04266044011845181 3.995151530164392e-08 7.398466743892866 -0.1786327762164559 DSISAVS(ph)SEKVSPSK ddPTM_PC-9_AZD4547_30min_R2 1 DSISAVSSEKVSPSK 15 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DSIS(0.001)AVS(0.549)S(0.159)EKVS(0.275)PS(0.017)K 63.54600000000001 0.018294 61272000.0 96976.0 109700.0 88468.0 57029.0 70549.0 104890.0 116120.0 102010.0 99224.0 77864.0 True False 127812.35077389295 145158.379699579 87294.8565160357 43881.84513926684 60754.48911438273 98331.21171867666 126454.45504575275 86246.6984566004 104468.77807018909 75138.00505995707 1.701034658451524 1.9318902542561323 1.1617936415317116 0.5840166385073827 0.8085720277761318 1.3086747730421158 1.6829626358172172 1.147843869261355 1.3903586871494293 1.0 16.1972551919849 -5.269473646385709 22.872619868947663 1.1351690796980545 1.8164624695006428 0.4655919330361237 0.29180914822868526 161.85313335784704 460782.0908033166 0.08561562012711549 0.18413663828883983 5.376830595143353e-06 5.269473646385709 0.6812933898025884 DSISAVSSEKVS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSISAVSSEKVSPSK 15 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DSISAVS(0.039)S(0.039)EKVS(0.82)PS(0.101)K 57.788000000000004 0.028895999999999998 50448000.0 61211.0 101760.0 57154.0 61650.0 65763.0 34561.0 68685.0 35994.0 34400.0 51954.0 True False 71572.81332764219 111862.06029158882 58516.76811775203 58195.95037199678 52877.212233645485 32748.560318836717 62178.659563662695 35049.19563879541 34903.034921593826 61372.8489323623 1.1661966907633872 1.8226636409671904 0.9534634473664747 0.9482360911114505 0.8615733692258661 0.5336001324450198 1.0131297576260223 0.5710863394564326 0.5687048186415415 1.0 15.905312934593928 -5.439411405247649 4.620467423372357 0.7795046795441728 1.491302826844053 0.6052168189119592 0.22519530804433924 0.1341983071897449 5.0249724085229195 0.05842460213541621 0.12501895270204777 3.6357046424967474e-06 5.439411405247649 0.7117981472998801 DSISAVSSEKVS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 1 DSISAVSSEKVSPSK 15 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DSISAVSSEKVS(0.991)PS(0.009)K 142.74 0.00045102 11054000.0 12283.0 28156.0 17983.0 24072.0 28402.0 27313.0 27181.0 27574.0 20776.0 24376.0 True False 12107.842167573672 28090.806511899496 16504.507156387433 25842.335181837985 26731.450200480427 26144.886659712753 28588.299182345556 28855.18870383602 18435.988099021015 28589.35912102166 0.42350869483712267 0.9825616024825272 0.5772954576044248 0.9039144624559353 0.9350139710136028 0.9144971228294694 0.9999629254132065 1.0092982001341504 0.6448548923737537 1.0 14.803190659424478 -4.287641489600327 0.7944645361452992 0.9144007239213431 3.915957390521859e-25 0.37873091420933747 0.15752068477997144 5.84842942285848 1.635667714925176 0.05647793003349795 5.675588030464649 5.156541417894926e-05 4.287641489600327 -0.9144007239213431 DSISS(ph)DSETSEPLSCR ddPTM_PC-9_AZD4547_30min_R2 1 DSISSDSETSEPLSCR 16 0 O75164 O75164 KDM4A Lysine-specific demethylase 4A 1 DSIS(0.31)S(0.676)DS(0.013)ET(0.001)SEPLSCR 128.85 1.9509000000000002e-05 29761000.0 112490.0 76581.0 106830.0 171840.0 140460.0 139610.0 111920.0 126660.0 115220.0 134850.0 True False 148259.4800626464 101334.31062692292 105413.3643985179 132224.94290153446 120959.55351608344 130880.16463003567 121880.66318223099 107087.60735724926 121310.29397370806 130128.9425451456 1.139327479059555 0.7787223091570658 0.8100685545949692 1.0161071035804483 0.929536128937027 1.005772905475117 0.9366145670471959 0.8229345852103377 0.9322314590516395 1.0 16.989582348272094 -4.737642003424566 24.93167476018255 0.9130311568160028 1.1393284900026515 0.4121966609523039 0.08046370554478628 2216.708044076119 2322243.3904403527 0.020830676172383104 1.279114187597575 1.8296077725524004e-05 4.737642003424566 0.22629733318664869 DSISS(ph)DSETSEPLSCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSISSDSETSEPLSCR 16 0 O75164 O75164 KDM4A Lysine-specific demethylase 4A 1 DSIS(0.283)S(0.701)DS(0.01)ET(0.004)S(0.001)EPLS(0.001)CR 76.156 0.011709 15640000.0 41128.0 22628.0 28604.0 45236.0 44528.0 43526.0 37639.0 56431.0 31610.0 35024.0 True False 48090.1580849727 24874.358296757782 29286.02784127407 42701.57357709074 35803.05804692254 41243.41993685619 34073.56143723814 54949.746043586856 32072.23644975526 41373.57395016855 1.1623399550373334 0.6012136714782516 0.7078438008895956 1.032097774016856 0.8653605339979743 0.9968541752407195 0.8235585709437926 1.328136314976555 0.7751865112833599 1.0 15.336421966019744 -6.467495752660414 1.067210243462127 1.006489556160857 0.8262790334869398 0.06462545373250927 0.2003680180583244 1.1547500425850252 2.796667812550805 0.09340641787362035 0.11414584227582542 3.408036577964052e-07 6.467495752660414 -0.18021052267391713 DSISS(ph)DSETSEPLSCR ddPTM_PC-9_Lapatinib_30min_R1 1 DSISSDSETSEPLSCR 16 0 O75164 O75164 KDM4A Lysine-specific demethylase 4A 1 DS(0.005)IS(0.287)S(0.708)DSETSEPLSCR 130.95 1.1932e-05 18965000.0 143250.0 120200.0 154410.0 145260.0 123500.0 149030.0 90995.0 107830.0 138610.0 117000.0 True False 141207.2287311676 119921.68428506595 141715.00583983658 155942.90497315503 116235.97281034205 142656.3343058979 95706.27585804553 112840.17545276842 122998.28217199178 137223.29410729944 1.0290324951735452 0.8739163788860455 1.0327328662510091 1.136417151239775 0.8470571528435492 1.0395926962251043 0.697449193889848 0.8223106447549273 0.8963367551562736 1.0 17.066165878983483 -7.23675261325974 24.926045475287935 0.839216667292594 0.989380448488565 0.2912261619309463 0.10520384368450232 884.6648527534172 893240.7483815864 0.03954840423870766 0.030620537347032593 5.797588498511347e-08 7.23675261325974 0.15016378119597096 DSITPDIATKPGQPLFLDSIS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 DSITPDIATKPGQPLFLDSISPK 23 1 Q2TB10 Q2TB10 ZNF800 Zinc finger protein 800 1 DSITPDIATKPGQPLFLDS(0.225)IS(0.775)PK;DSITPDIATKPGQPLFLDS(0.241)IS(0.759)PK 84.365 1.716e-05 10050500.0 97159.0 103308.0 85463.0 85274.0 95342.0 85801.0 90697.0 82268.0 84799.0 78547.0 True False 95773.49484322133 103068.79667322483 78436.56203672008 91545.33442572496 89734.17100958413 82131.4912418999 95392.8468761708 86090.47161409953 75248.04364694281 92123.74429270117 1.039617913693607 1.118808158141601 0.8514261186291631 0.9937213812636788 0.9740612661647279 0.8915344450280562 1.0354859934164513 0.93450903754593 0.8168148637973305 1.0 16.491285429007746 -5.248635735271408 24.985609931130195 0.9400704072124758 1.0792130462162457 0.4155121949652386 0.06730635977627009 734.3349424725736 1433008.779046499 0.01668675219800151 0.0435437058934113 5.641106055264177e-06 5.248635735271408 0.13914263900376989 DSIVAELDR ddPTM_PC-9_Lapatinib_30min_R1 1 DSIVAELDR 9 0 M0QXB4;O14579-3;O14579 M0QXB4 COPE Coatomer subunit epsilon 0 98.03299999999999 0.021159 1239600.0 6438.8 8396.9 8407.5 8096.0 6762.4 9018.1 7019.1 5507.7 7502.7 7093.6 False True 6346.981531268691 8377.457493953998 7716.267803888528 8691.406847464285 6364.648927389932 8632.416885217865 7382.51465327993 5763.607848847379 6657.666919066466 8319.71930837214 0.762884094524886 1.006939919898951 0.9274673240626811 1.044675490279836 0.7650076512779922 1.0375851113788246 0.887351409301862 0.6927646997714761 0.8002273480989739 1.0 13.022319140041601 -7.534484826431502 24.843486670991403 0.8059091877343717 0.9292794094387526 0.10103061570345939 0.11672987291328339 344.9426628142952 738358.9252515219 0.05157174368251548 0.029805990378173598 2.9208898097362544e-08 7.534484826431502 0.12337022170438094 DSLGDFIEHYAQLGPS(ph)SPEQLAAGAEEGGGPR ddPTM_PC-9_AZD4547_30min_R2 2 DSLGDFIEHYAQLGPSSPEQLAAGAEEGGGPR 32 0 Q96QR8 Q96QR8 PURB Transcriptional activator protein Pur-beta 1 DSLGDFIEHYAQLGPS(0.509)S(0.491)PEQLAAGAEEGGGPR;DSLGDFIEHYAQLGPS(0.86)S(0.14)PEQLAAGAEEGGGPR 136.96 4.877099999999999e-18 38205000.0 59664.0 65240.0 98940.0 113852.0 105311.0 102705.0 86276.0 104050.0 82709.0 88675.0 True False 78635.91091170534 86327.55416226554 97627.99095375242 87605.18039586532 90690.38545018011 96282.84011408774 93954.39686124166 87971.46333113674 87080.82888622991 85570.51524056926 0.9189603532318548 1.0088469599554002 1.1409068962514166 1.0237776429132848 1.0598321769504024 1.1251871026299456 1.0979762900468966 1.0280581235699884 1.0176499304861566 1.0 16.384826156971677 -4.899942619815473 3.730177585480196 1.0654359930355062 0.9190253839549981 0.4816219044169998 0.045121333291459544 0.19749752933391598 4.796213141772286 0.011494242444603673 0.06454414056808663 1.2590917554797432e-05 4.899942619815473 -0.14641060908050807 DSLGDFIEHYAQLGPS(ph)SPEQLAAGAEEGGGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DSLGDFIEHYAQLGPSSPEQLAAGAEEGGGPR 32 0 Q96QR8 Q96QR8 PURB Transcriptional activator protein Pur-beta 1 DSLGDFIEHYAQLGPS(0.682)S(0.318)PEQLAAGAEEGGGPR;DSLGDFIEHYAQLGPS(0.602)S(0.398)PEQLAAGAEEGGGPR 120.64 5.2688e-18 34718000.0 74000.0 72514.0 84844.0 88826.0 105908.0 79266.0 78223.0 87044.0 75338.0 55519.0 True False 86526.73843337837 79712.71069166932 86867.00273266177 83849.3671977776 85156.08766693913 75109.15142018198 70813.15115452284 84759.18723074145 76439.67572450665 65584.15521183777 1.3193238237787122 1.21542635464612 1.3245120327018025 1.2785003775217187 1.2984247093201662 1.1452331920351544 1.0797295615960187 1.2923729360692082 1.1655204748403847 1.0 16.001059688929175 -6.763401228832371 24.999999996562387 1.1512919178459617 1.2848333806860937 0.49856088935317955 0.0748061407379388 50.28945772827437 640836.1530272306 0.025214662878225165 0.023356471902194427 1.724244189601153e-07 6.763401228832371 0.1335414628401319 DSLGDFIEHYAQLGPS(ph)SPEQLAAGAEEGGGPRR ddPTM_PC-9_AZD4547_30min_R2 1 DSLGDFIEHYAQLGPSSPEQLAAGAEEGGGPRR 33 1 Q96QR8 Q96QR8 PURB Transcriptional activator protein Pur-beta 1 DSLGDFIEHY(0.002)AQLGPS(0.499)S(0.499)PEQLAAGAEEGGGPRR 40.044000000000004 0.022633 3687000.0 7882.6 5744.7 8599.6 20399.0 13577.0 11390.0 7190.4 9475.7 7180.5 11777.0 True False 10389.102831734524 7601.561931268651 8485.56368512118 15696.325711408306 11692.067906079084 10677.78149943489 7830.331670349477 8011.448294924093 7560.046570718714 11364.690814639816 0.9141562230933239 0.6688753838755066 0.7466603204189427 1.3811485035024926 1.0288065110418618 0.9395575888153455 0.6890052530300751 0.7049420371915328 0.6652223711163334 1.0 13.472270814584796 -7.2496908617178235 21.90716063340573 0.7402042788919189 0.9483229960304109 0.1643049360320219 0.1976864685217605 254.02927912449746 473682.47277028393 0.08219528515756487 0.06294356470804292 5.627417519164184e-08 7.2496908617178235 0.20811871713849206 DSLGDFIEHYAQLGPS(ph)SPEQLAAGAEEGGGPRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSLGDFIEHYAQLGPSSPEQLAAGAEEGGGPRR 33 1 Q96QR8 Q96QR8 PURB Transcriptional activator protein Pur-beta 1 DSLGDFIEHYAQLGPS(0.5)S(0.5)PEQLAAGAEEGGGPRR 83.755 5.7803e-10 4198500.0 18876.0 9552.2 16611.0 30033.0 24993.0 27881.0 18382.0 25371.0 24984.0 18432.0 True False 22071.333982006046 10500.479287709459 17007.0692375683 28350.348378299717 20095.801063751693 26418.871278304636 16640.723885844793 24705.038132796526 25349.343734915685 21773.57569236828 1.0136752131962474 0.48225791831655457 0.7810875658576071 1.3020529461422647 0.9229444601878298 1.2133455547939491 0.7642623389449731 1.1346339472140874 1.1642251182381922 1.0 14.41029072828111 -5.602174108665535 8.561483085713443 1.0635607783419878 0.7192202384055314 0.3674624862217617 0.18730100181484188 0.2478895685813788 23.832976960958064 0.04812251056409968 0.08353885012349348 2.4993431740983016e-06 5.602174108665535 -0.3443405399364564 DSLGDFIEHYAQLGPSS(ph)PEQLAAGAEEGGGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSLGDFIEHYAQLGPSSPEQLAAGAEEGGGPR 32 0 Q96QR8 Q96QR8 PURB Transcriptional activator protein Pur-beta 1 DSLGDFIEHY(0.001)AQLGPS(0.317)S(0.682)PEQLAAGAEEGGGPR 45.791000000000004 0.0091964 2427400.0 11805.0 10488.0 10745.0 11038.0 11525.0 11778.0 11344.0 10143.0 10071.0 10309.0 True False 13803.35334062202 11529.179327222717 11001.201550639422 10419.576645678835 9266.75898290474 11160.340946015991 10269.414196552238 9876.756997396844 10218.269322539869 12177.940094000898 1.1334719364748587 0.9467265595190624 0.9033712980784688 0.8556107654702401 0.7609463432546966 0.9164391399423785 0.8432800717759451 0.8110367534376636 0.8390802749615756 1.0 13.571982500683868 -4.457195932209564 1.2060069520734038 0.8517704518422292 1.4699321093415285 0.6376924909653823 0.06112179631393542 1.7071757966738859 1.2689114911914317 0.017458284030885795 1.5940274934096974 3.489828361471352e-05 4.457195932209564 0.6181616574992993 DSLIFLVDASK ddPTM_PC-9_Lapatinib_30min_R1 1 DSLIFLVDASK 11 0 P12956;P12956-2 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 139.86 0.00053173 2794700.0 54483.0 43402.0 53837.0 42853.0 42045.0 41136.0 46927.0 42391.0 48428.0 52217.0 False True 53706.062429041434 43301.505335610906 49410.72967682978 46004.55257341733 39571.995763650455 39376.70917269958 49356.65044442555 44360.64061595391 42973.52867055205 61242.638875221055 0.8769390642761976 0.7070483266378454 0.8068027535113531 0.7511850145312876 0.6461510557093483 0.6429623199765728 0.8059197211437502 0.7243424096459428 0.7016929619592088 1.0 15.902248827804723 -10.58127579737187 5.097803525538338 1.0000041599996503 0.7374571318667538 0.5540535822344244 0.06984371256204178 3.3407810929751533e-06 6.171559740082488e-07 0.06841559645521383 0.01659295665487733 2.6225525705299783e-11 10.58127579737187 -0.26254702813289654 DSLIIIDELGR ddPTM_PC-9_Lapatinib_30min_R1 2 DSLIIIDELGR 11 0 P43246-2;A0A2R8Y713;A0A2R8YFH0;E9PHA6;A0A2R8Y6P0;A0A2R8YG02;P43246 P43246-2 MSH2 DNA mismatch repair protein Msh2 0 ; 109.42 0.0071069 729120.0 12173.7 14567.8 14972.1 10702.4 12636.6 12524.1 11119.0 11025.4 13060.5 11587.1 False True 12000.100805616841 14534.06915414297 13741.15173197734 11489.4901981598 11893.340032511485 11988.473438103034 11694.687414315165 11537.680334201554 11589.488956837886 13589.914796159755 0.8830151612876804 1.069474634105139 1.0111286154538894 0.8454424012582114 0.8751592788405348 0.8821595733249735 0.8605416288275667 0.8489884231990826 0.8528007077802172 1.0 13.730248790508092 -5.75777501482155 24.999996319825705 0.873421868240065 0.9960330121729938 0.39223615144235124 0.060387880284305806 79.30260257296983 541029.0387145143 0.015636912004799483 0.025786426069715207 1.7467268060601952e-06 5.75777501482155 0.12261114393292882 DSLITPHVS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 DSLITPHVSR 10 0 P49792;J3KQ37;F8VYC4;A0A286YES2;A0A1W2PNU4;J3KNE0;P0DJD0;P0DJD1;Q7Z3J3;A6NKT7;H7BZ48;Q99666;O14715 P49792;Q99666 RANBP2;RGPD8;RGPD1;RGPD3;RGPD2;RGPD4;RGPD6;RGPD5 E3 SUMO-protein ligase RanBP2;RANBP2-like and GRIP domain-containing protein 1;RANBP2-like and GRIP domain-containing protein 2;RanBP2-like and GRIP domain-containing protein 4;RanBP2-like and GRIP domain-containing protein 3;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8 1 DSLITPHVS(1)R;DSLIT(0.005)PHVS(0.995)R 90.689 0.0048456 13099000.0 114784.0 129476.0 181224.0 186175.0 170758.0 185014.0 171786.0 199043.0 171236.0 175709.0 True False 151282.9243444825 171326.5849588213 178820.85135034175 143255.23012507672 147051.1991976324 173445.04533243572 187074.62120642178 168285.4779031178 180287.18537477753 169557.48139165714 0.8922220541542332 1.0104336508931608 1.0546326230058074 0.8448770820921465 0.8672645877415579 1.0229277051585757 1.1033109224729647 0.9924980987090675 1.063280628463312 1.0 17.371414916296594 -6.92931998792398 9.009190487713587 1.0425426089075767 0.9401040027662987 0.3783480295111239 0.06570399113740949 0.3653423011439434 42.80030205281457 0.024718144691576738 0.021795691186533392 1.1767386336851605e-07 6.92931998792398 -0.10243860614127798 DSLITPHVS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DSLITPHVSR 10 0 P49792;J3KQ37;F8VYC4;A0A286YES2;A0A1W2PNU4;J3KNE0;P0DJD0;P0DJD1;Q7Z3J3;A6NKT7;H7BZ48;Q99666;O14715 P49792;Q99666 RANBP2;RGPD8;RGPD1;RGPD3;RGPD2;RGPD4;RGPD6;RGPD5 E3 SUMO-protein ligase RanBP2;RANBP2-like and GRIP domain-containing protein 1;RANBP2-like and GRIP domain-containing protein 2;RanBP2-like and GRIP domain-containing protein 4;RanBP2-like and GRIP domain-containing protein 3;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8 1 DSLIT(0.018)PHVS(0.982)R;DSLIT(0.031)PHVS(0.969)R;DSLIT(0.003)PHVS(0.997)R 79.744 0.010544 16310900.0 100237.0 147843.0 156386.0 144031.0 156744.0 122896.0 142951.0 117386.0 114632.0 97880.0 True False 117205.14432900696 162519.87597965167 160114.83533720768 135961.4100248026 126031.13839621893 116451.1174139565 129409.6464043848 114304.7418807478 116308.2761375624 115624.86918234605 1.013667259974744 1.405578896036197 1.3847785210005192 1.1758837954695096 1.0900002679999723 1.007145938736652 1.1192198297781377 0.9885826698794673 1.0059105533268848 1.0 16.819092207805546 -6.186016482397864 2.5375475404757766 1.0324543872302396 1.2806225559592548 0.4950450152336211 0.10644987525312641 0.23401024160884323 2.954853585288455 0.03415266260145777 0.045568731660178906 6.516036638487626e-07 6.186016482397864 0.24816816872901515 DSLITPHVS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 3 DSLITPHVSR 10 0 P49792;J3KQ37;F8VYC4;A0A286YES2;A0A1W2PNU4;J3KNE0;P0DJD0;P0DJD1;Q7Z3J3;A6NKT7;H7BZ48;Q99666;O14715 P49792;Q99666 RANBP2;RGPD8;RGPD1;RGPD3;RGPD2;RGPD4;RGPD6;RGPD5 E3 SUMO-protein ligase RanBP2;RANBP2-like and GRIP domain-containing protein 1;RANBP2-like and GRIP domain-containing protein 2;RanBP2-like and GRIP domain-containing protein 4;RanBP2-like and GRIP domain-containing protein 3;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8 1 DSLIT(0.003)PHVS(0.997)R;DSLIT(0.01)PHVS(0.99)R;DSLIT(0.003)PHVS(0.997)R 82.069 0.008739100000000001 23958000.0 156673.0 202718.0 243218.0 194526.0 244119.0 242388.0 226432.0 229882.0 241987.0 186444.0 True False 154438.81428969026 202248.6189259568 223221.55488863066 208832.09095971333 229760.40037641994 232021.63027402532 238155.54101971484 240563.15694550076 214731.87582392176 218670.59697898605 0.7062623709969184 0.9249008404426344 1.0208119334401504 0.9550076409211148 1.0507146527729085 1.0610554572927895 1.0891063741990026 1.1001166149860493 0.9819878794429651 1.0 17.738399719311154 -4.178143229774905 0.9610384138763418 1.0473760275668969 5.290876095308271e-15 0.8458695753619274 0.04260252392050204 2.031959220984482 0.6608667726353692 0.014288729615247317 2.920371906353226 6.635242048633471e-05 4.178143229774905 -1.0473760275668915 DSLLQDGEFSMDLR ddPTM_PC-9_AZD4547_30min_R2 5 DSLLQDGEFSMDLR 14 0 P07737;K7EJ44 P07737 PFN1 Profilin-1 0 ;;;; 211.22 1.0071999999999999e-10 58392300.0 105828.1 99865.6 128445.5 186224.0 149807.8 134293.9 126307.3 153116.0 121253.3 112982.7 False True 139479.2344387747 132145.2022217528 126742.22874520127 143292.93393211908 129009.57284085688 125896.48120342066 137548.40501033806 129455.44045564943 127662.50189448197 109027.21006225728 1.2793066461035603 1.2120387391945056 1.16248254608027 1.3142859828321316 1.1832786766458498 1.1547253307823855 1.2615970355638235 1.187368184343405 1.1709233119107008 1.0 16.734328709649198 -14.394406715101507 0.2147509836228076 7.652705276443578e-16 1.2424669195435531 0.6603013501308194 0.04787939875540601 86.47326043410914 0.9062885235211704 37.212998508873675 0.0966720838414317 4.0326755756757815e-15 14.394406715101507 1.2424669195435525 DSLLQDGEFSMDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DSLLQDGEFSMDLR 14 0 P07737;K7EJ44 P07737 PFN1 Profilin-1 0 ; 154.28 0.0013375 13738000.0 24373.3 26534.2 26817.8 30948.0 34351.0 28652.8 28746.0 25563.2 22967.1 21085.8 False True 28499.21829538186 29168.3400175813 27457.23805907288 29214.08389476975 27620.16814071678 27150.196727628376 26022.9707769826 24892.193086449264 23302.950388015608 24908.488624899033 1.1441568665428161 1.171020066967212 1.1023245317110917 1.1728565443977501 1.1088656785505282 1.0899977568485824 1.0447430660634105 0.9993457837328003 0.9355425268445032 1.0 14.604349865218381 -7.3335941393126625 1.0931666796922281 0.9658932610417377 1.1459053938814372 0.8856359607254424 0.02561541545882582 0.15230254389238118 0.3489825471975902 0.017855964164527786 0.009554390245474744 4.638802266528063e-08 7.3335941393126625 0.18001213283969952 DSLLQDGEFSMDLR ddPTM_PC-9_Lapatinib_30min_R1 4 DSLLQDGEFSMDLR 14 0 P07737;K7EJ44 P07737 PFN1 Profilin-1 0 ;;; 220.37 3.6028e-15 29374800.0 68997.9 62468.3 72181.6 62994.9 61800.7 72538.9 62974.3 66357.7 69330.2 55218.7 False True 68013.97729333483 62323.65848939092 66247.10747703377 67627.75509082613 58165.70433085103 69436.58034343483 66234.80111838362 69440.92099269383 61521.50279662808 64763.178720707205 1.0501951670199323 0.9623316785941471 1.0229131550618609 1.0442315591467874 0.8981292376288702 1.0721613996570765 1.0227231341442153 1.0722284230698358 0.9499456946352351 1.0 15.98288617760585 DSLS(ph)PVLHPSDLILTR ddPTM_PC-9_AZD4547_30min_R2 3 DSLSPVLHPSDLILTR 16 0 Q9HCN4-3;Q9HCN4-2;Q9HCN4-4;Q9HCN4;Q9HCN4-5 Q9HCN4-3 GPN1 GPN-loop GTPase 1 1 DS(0.314)LS(0.686)PVLHPSDLILTR;DS(0.199)LS(0.801)PVLHPSDLILTR;DS(0.072)LS(0.928)PVLHPSDLILTR 75.743 0.0079885 17941400.0 2407.0299999999997 2550.8599999999997 23148.9 57909.0 31005.4 29829.6 12693.9 41332.0 18452.5 28751.3 True False 3172.4154706657637 3375.375610213927 22841.930460777447 44558.974735131305 26700.83540216133 27964.350396448004 13823.632508657269 34945.08911487305 19427.861478474624 27744.72573821462 0.11434301065359564 0.1216582799218232 0.8232891064162068 1.6060340677203857 0.9623751791276325 1.0079159066233219 0.49824361715052307 1.2595218797474326 0.7002362056769357 1.0 14.759925921299592 -5.311683304236744 4.2545414432395186 1.0057400321176637 0.10657332730673566 0.6071763554048575 0.28039171807674107 0.13175211078000795 5.113671636973124 0.07500960071685919 0.17529705627598421 4.8788413476951396e-06 5.311683304236744 -0.8991667048109281 DSLS(ph)PVLHPSDLILTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DSLSPVLHPSDLILTR 16 0 Q9HCN4-3;Q9HCN4-2;Q9HCN4-4;Q9HCN4;Q9HCN4-5 Q9HCN4-3 GPN1 GPN-loop GTPase 1 1 DS(0.059)LS(0.941)PVLHPSDLILTR;DS(0.195)LS(0.805)PVLHPSDLILTR;DS(0.284)LS(0.716)PVLHPSDLILTR;DSLS(1)PVLHPSDLILTR 88.781 0.0022186 13448200.0 5677.68 10924.300000000001 31514.5 29971.100000000002 42258.799999999996 41169.5 30503.399999999998 24966.699999999997 31161.899999999998 18616.300000000003 True False 6638.799084708418 12008.792307816468 32265.925199406793 28291.91643461721 33978.49149733405 39010.49894523731 27613.897126508415 24311.350579405276 31617.583834977162 21991.28782345028 0.301883142906673 0.5460704440879066 1.4672139921246548 1.2865056681422857 1.5450887537882747 1.7739069789100164 1.255674399252894 1.1054991765184854 1.437732255100674 1.0 14.424644471332291 -5.181446434452761 4.022001877142531 1.3791616804933933 0.3583851120735801 0.7582722130049017 0.21216988937524245 0.10566494443935283 3.188342925214858 0.05691901590053769 0.16914491567630263 6.58496643404207e-06 5.181446434452761 -1.0207765684198131 down DSLS(ph)PVLHPSDLILTR ddPTM_PC-9_Lapatinib_30min_R1 3 DSLSPVLHPSDLILTR 16 0 Q9HCN4-3;Q9HCN4-2;Q9HCN4-4;Q9HCN4;Q9HCN4-5 Q9HCN4-3 GPN1 GPN-loop GTPase 1 1 DS(0.032)LS(0.968)PVLHPSDLILTR;DSLS(1)PVLHPSDLILTR;DS(0.053)LS(0.947)PVLHPSDLILTR 132.4 6.7241e-06 19642600.0 13187.2 10419.800000000001 50342.9 17523.800000000003 35327.4 46903.9 23062.2 22303.800000000003 56318.0 20628.1 True False 12999.148109763695 10395.673593290605 46203.901091213746 18812.55870968313 33249.51178834073 44897.92953533117 24256.24787178874 23340.11597202503 49974.873785168704 24193.639599784492 0.5372960961970966 0.42968622188549116 1.909754045093129 0.7775828284162216 1.3743079726060277 1.855774090961126 1.002587798819852 0.9647211563915722 2.065620328807984 1.0 14.562340198788014 -5.238110263549529 24.788278706717193 1.3509292359369356 0.48349084444572893 0.4092273059612521 0.42504698937386964 683.6618562847875 726419.8199900228 0.1040295807676385 0.27486283525742805 5.77949292534053e-06 5.238110263549529 -0.8674383914912067 DSLS(ph)SPGNFVLTCQWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSLSSPGNFVLTCQWK 16 0 O75815;O75815-3 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 DSLS(0.918)S(0.082)PGNFVLTCQWK 232.26 8.38e-30 8508100.0 58229.0 56294.0 58424.0 65497.0 70564.0 65489.0 67038.0 64543.0 60658.0 55065.0 True False 68086.01962482672 61882.496285914865 59817.04973425386 61827.41543413906 56737.490747912365 62054.64155320438 60687.6753269101 62848.81463896133 61545.0084963383 65047.84860569987 1.046706710279433 0.951338093609023 0.9195853670249186 0.9504913192274491 0.8722423871669861 0.9539845342058982 0.9329697542309231 0.9661935941945073 0.9461497930455053 1.0 15.989213721546864 -10.473458150312002 13.958273486460824 1.000000002532771 0.9460526384886364 0.11864628443997671 0.04119113268097988 0.0 0.0 0.04001423645796105 0.009704877849683208 3.361567603813487e-11 10.473458150312002 -0.053947364044134694 DSLSS(ph)PGNFVLTCQWK ddPTM_PC-9_AZD4547_30min_R2 1 DSLSSPGNFVLTCQWK 16 0 O75815;O75815-3 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 DS(0.003)LS(0.105)S(0.892)PGNFVLTCQWK 117.95 0.00013393 10521000.0 69018.0 57016.0 80360.0 103030.0 89710.0 93867.0 85570.0 102390.0 84313.0 93205.0 True False 90964.28833641864 75445.30699135087 79294.37389370879 79278.02529763218 77255.31500731801 87997.4816512252 93185.56422894483 86567.97818813166 88769.61305159896 89941.9213193942 1.011366968839746 0.8388224966135183 0.881617523069418 0.8814357547033792 0.8589466833043896 0.9783811637593991 1.0360637493836948 0.9624875354921397 0.9869659414586861 1.0 16.456706082417348 -6.849073210639849 5.980590549037692 0.9947829259718818 0.8901463243185241 0.5312824707249643 0.04624198034792527 0.16014989868638374 8.726580872302643 0.015980143442090228 0.01413455915556628 1.4155551344368113e-07 6.849073210639849 -0.10463660165335764 DSLSS(ph)PGNFVLTCQWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSLSSPGNFVLTCQWK 16 0 O75815;O75815-3 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 DS(0.001)LS(0.026)S(0.973)PGNFVLTCQWK 152.07 3.1283e-05 9285000.0 27172.0 29742.0 30189.0 30339.0 38631.0 31919.0 36976.0 32299.0 27818.0 25932.0 True False 31771.68292853719 32694.589201969677 30908.820252420064 28639.204190365104 31061.532864953864 30245.111449811884 33473.3655969425 31451.185473619313 28224.785623514428 30633.266322400963 1.0371627561408214 1.06729033913244 1.0089952513427405 0.9349053375161083 1.013980440023783 0.9873289753530058 1.0927129103586541 1.0267003571414857 0.9213769542712688 1.0 14.902811584419462 -5.351651619878214 5.947196042678182 1.000105659011694 1.0518817919332693 0.18530181623466102 0.045360160353803566 0.388874101741823 20.45968777722231 0.012452486266953071 0.026479886789655287 4.449880825954961e-06 5.351651619878214 0.051776132921575346 DSLSS(ph)PGNFVLTCQWK ddPTM_PC-9_Lapatinib_30min_R1 1 DSLSSPGNFVLTCQWK 16 0 O75815;O75815-3 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 DS(0.002)LS(0.042)S(0.957)PGNFVLTCQWK 108.06 0.00083717 9468400.0 81330.0 71940.0 84208.0 80214.0 69080.0 86301.0 71332.0 68445.0 93065.0 60335.0 True False 80170.2192859047 71773.42734998047 77284.74329228004 86113.20514605995 65016.85021650547 82610.10740745686 75025.22192984335 71625.20457075702 82583.03968210393 70763.82435866594 1.132926604977743 1.0142672191683333 1.092150459542193 1.2169099949939928 0.9187865523910639 1.1674059190010437 1.060220000965162 1.0121726068354528 1.167023411051562 1.0 16.110724398665845 -11.00688480496714 2.9365409611060445 0.9974637365632513 1.0831617958875093 0.08486514087649855 0.08479813137746342 132925051.42597142 149222815.09161434 2732159.5243491973 0.019882476529092783 9.842721457489244e-12 11.00688480496714 0.085698059324258 DSLSVSSNDAS(ph)PPASVASLQPHMIGAQSSPGPK ddPTM_PC-9_AZD4547_30min_R2 1 DSLSVSSNDASPPASVASLQPHMIGAQSSPGPK 33 0 E7EPJ7;O75962-4;O75962;O75962-5;O75962-2;E7EWP2 E7EPJ7 TRIO Triple functional domain protein 1 DSLS(0.003)VS(0.013)S(0.033)NDAS(0.574)PPAS(0.188)VAS(0.188)LQPHMIGAQSSPGPK 62.787 0.00014765 5387300.0 3889.4 1467.6 16393.0 55428.0 34512.0 19430.0 5986.0 20738.0 10606.0 23983.0 True False 5126.148295454324 1941.972999517793 16175.61810900408 42649.93095406341 29720.604520483255 18215.039028447743 6518.742403581441 17533.418611831934 11166.611507421858 23143.36246985706 0.22149539861076137 0.0839105813620257 0.6989312002554479 1.8428580120806806 1.2841956115578574 0.7870524022674673 0.28166790422401844 0.7576003113060271 0.48249736925504005 1.0 14.498310866560612 -5.365199639705712 4.7489026125148746 0.9160397250368504 0.15746302836356935 0.3525804550051821 0.40709272458443574 0.25981635646706974 9.248734712820074 0.12159466154340827 0.2654302389366629 4.313207585265305e-06 5.365199639705712 -0.758576696673281 DSLYAQGK ddPTM_PC-9_Lapatinib_30min_R1 1 DSLYAQGK 8 0 H0Y5B4;H7BZ11;J3KQN4;P83881;H7BY91;H0Y3V9 H0Y5B4 RPL36A;RPL36A-HNRNPH2 60S ribosomal protein L36a 0 93.429 0.033319999999999995 6142000.0 48858.0 47154.0 45625.0 43161.0 42493.0 42162.0 40893.0 41034.0 39259.0 43892.0 False True 48161.27596054011 47044.817810133114 41873.8886175931 46335.20392087526 39993.64528445236 40358.82954442238 43010.2394490143 42940.589441981865 34837.23800440246 51478.67371758626 0.935557823901107 0.9138700438986166 0.813422056040423 0.9000854251815374 0.7768973517821933 0.7839912458862534 0.8354962617135384 0.8341432741168777 0.6767314596238575 1.0 15.651687264387991 -5.000227271089022 0.9339890888913268 0.8131986137149737 0.9850863167812444 0.1780096880829214 0.07999091700315408 2.406076609452011 2.0937159070596842 0.026829539315569785 0.39125822877139177 9.9947682588168e-06 5.000227271089022 0.17188770306627066 DSNAPKS(ph)PLTGYVR ddPTM_PC-9_AZD4547_30min_R2 2 DSNAPKSPLTGYVR 14 1 H0YNS8;H0YKM5;Q9NP66 H0YNS8 HMG20A High mobility group protein 20A 1 DS(0.001)NAPKS(0.998)PLT(0.001)GYVR;DS(0.001)NAPKS(0.998)PLT(0.001)GYVR 117.2 0.00064478 49072000.0 35788.0 30545.0 45233.0 77897.0 60765.0 48115.0 42462.0 51455.0 38828.0 55378.0 True False 47167.839563356676 40418.073909969346 44633.180865282855 59939.05014665284 52328.82863024937 45106.36144383754 46241.03574020631 43503.81206827138 40880.36881106696 53439.23307575135 0.8826443952983976 0.7563370876351424 0.835213724007122 1.121630058980971 0.9792211754998813 0.8440682780738681 0.8653012604926155 0.8140800225670103 0.7649879397243238 1.0 15.705611682912506 -10.124742996396705 12.887612981545159 0.9999999995369223 0.8766559833557237 0.12034404474850835 0.10214610422178334 0.0 0.0 0.10868158297100633 0.02635915565581111 7.50338107558239e-11 10.124742996396705 -0.12334401618119861 DSNAPKS(ph)PLTGYVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DSNAPKSPLTGYVR 14 1 H0YNS8;H0YKM5;Q9NP66 H0YNS8 HMG20A High mobility group protein 20A 1 DS(0.008)NAPKS(0.824)PLT(0.168)GYVR;DSNAPKS(1)PLTGYVR;DSNAPKS(0.903)PLT(0.097)GYVR 197.73 4.3600000000000004e-07 55937000.0 70954.0 40927.0 50246.0 85591.0 79148.0 78832.0 79918.0 104889.0 76707.0 58888.0 True False 82965.11079462066 44989.96208287987 51444.05519901615 80795.61375976603 63639.51756867196 74697.9111441953 72347.58848378551 102135.77488908167 77828.69475961344 69563.92824284846 1.192645569194835 0.6467426900594142 0.7395219979444573 1.1614584713748142 0.9148350183230839 1.0738023718761833 1.040015857517696 1.468228972529046 1.118808220374108 1.0 16.08605178281586 -6.822764834310217 1.0447612465658629 1.2045461408517206 0.8833023850330657 0.2242316434031364 0.19512697578205584 0.653240629746981 1.5147044133138048 0.11168100252191511 0.09523470219812992 1.503956121355825e-07 6.822764834310217 -0.32124375581865494 DSNAPKSPLT(ph)GYVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSNAPKSPLTGYVR 14 1 H0YNS8;H0YKM5;Q9NP66 H0YNS8 HMG20A High mobility group protein 20A 1 DSNAPKS(0.008)PLT(0.991)GY(0.001)VR 130.64 0.00019411 23712000.0 12272.0 7940.3 9273.8 15300.0 17194.0 16751.0 12701.0 18735.0 12774.0 9942.8 True False 14349.407216951584 8728.560508385443 9494.922563082357 14442.790603269266 13824.959128161745 15872.54807154983 11497.869332723021 18243.226101373337 12960.795583966268 11745.350932838503 1.2217095341810922 0.743150252239931 0.8083983711832539 1.2296602022242746 1.1770579872167908 1.3513898530841009 0.9789293992550232 1.5532295463703518 1.1034830426164226 1.0 13.51980219903001 -5.771402671507921 24.85279617673871 1.218410755315983 0.906292474417675 0.28654504904327205 0.19636018916264236 196.3260025966339 489723.1057358906 0.05253353505193564 0.07898391003452743 1.692767563219594e-06 5.771402671507921 -0.31211828089830806 DSNNLCLHFNPR ddPTM_PC-9_AZD4547_30min_R2 2 DSNNLCLHFNPR 12 0 P09382 P09382 LGALS1 Galectin-1 0 ; 145.09 8.8538e-05 31339000.0 88232.0 91957.0 156087.0 229850.0 175718.0 128498.0 126177.0 162148.0 139834.0 141870.0 False True 116287.94066039131 121680.30193285487 154017.18439456593 176861.63364710019 151322.58881346398 120462.99974665335 137406.50856276244 137091.75239036177 147225.3397632311 136903.17448186714 0.8494174156333656 0.8888055546803368 1.1250081305818482 1.2918738686408295 1.1053256389866013 0.8799138530027929 1.0036765698297372 1.0013774546076695 1.0753975597748548 1.0 17.062796374328087 -5.172005957122044 5.747374034643196 1.0615033925171569 0.8619707437204658 0.36245737136850664 0.10168916486194116 0.27168618129505073 13.756911049660747 0.029392114301052666 0.08095838724461386 6.729674252746082e-06 5.172005957122044 -0.19953264879669108 DSNNLCLHFNPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSNNLCLHFNPR 12 0 P09382 P09382 LGALS1 Galectin-1 0 103.46 0.0017523 19484000.0 77087.0 90248.0 85069.0 101800.0 121240.0 76715.0 90633.0 80796.0 83185.0 85738.0 False True 90136.30656234878 99207.22501174627 87097.36758597886 96096.47604005306 97483.89232862226 72691.93035096077 82047.5861139034 78675.19061043828 84401.42325444147 101281.6206983654 0.8899571900689728 0.9795185377927843 0.8599523485645065 0.9488046831936605 0.9625032820016433 0.7177208446086206 0.8100935347219179 0.7767963236365157 0.8333340508620399 1.0 16.628012870362177 -6.741227011391806 24.99998944593299 0.812545225972729 0.9283602206263089 0.30053400868368807 0.07496831893154259 253.63292127407567 313709.2783661544 0.023242335364763334 0.023215337619355254 1.8145669170321837e-07 6.741227011391806 0.1158149946535798 DSNNLCLHFNPR ddPTM_PC-9_Lapatinib_30min_R1 2 DSNNLCLHFNPR 12 0 P09382 P09382 LGALS1 Galectin-1 0 ; 112.84 0.0007593999999999999 29954000.0 91705.0 84546.0 110897.0 90320.0 101266.0 93422.0 75364.0 83157.0 106299.0 76401.0 False True 90397.26988336268 84350.23893149059 101779.47673479964 96962.4340986877 95309.7329766161 89426.5588373186 79265.979161116 87020.77779955343 94326.48724190581 89606.81105206658 1.008821414600245 0.9413373597513516 1.1358453173348626 1.0820877672161227 1.063643844230053 0.9979884094453129 0.8845977022333495 0.9711402155466673 1.0526709536298176 1.0 16.451320775867828 -6.930952743954196 5.58508404747911 0.9702734659174795 1.046809166142112 0.22385795998434632 0.06089846932586488 0.30623959229590103 17.59293388814345 0.02328943896594641 0.02041129828899128 1.1723229203157057e-07 6.930952743954196 0.07653570022463241 DSPAFPDS(ph)PWR ddPTM_PC-9_AZD4547_30min_R2 4 DSPAFPDSPWR 11 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 DSPAFPDS(1)PWR;DSPAFPDS(1)PWR;DSPAFPDS(1)PWR;DSPAFPDS(1)PWR 135.94 7.651e-05 12940300.0 41498.8 45226.7 56219.1 54815.0 58966.0 58472.0 49288.5 64526.0 52156.0 51986.0 True False 54694.55517133752 59845.34631867772 55473.59800109258 42178.248633307834 50779.58872724899 54815.73659657216 53675.08101552352 54554.98935997049 54912.85968141565 50165.9859633069 1.0902717074342556 1.1929466783021196 1.1058010111007854 0.8407738395525294 1.012231450297636 1.0926873167940174 1.0699496877183536 1.0874896269331547 1.0946233513995074 1.0 15.61442188487291 -5.534792209580451 24.999921708079853 1.0308538033673582 1.143550420910884 0.28817665804818615 0.07438669016524341 278.52168279617797 584464.6665973668 0.02161271961108307 0.03747137050231722 2.9188232058815382e-06 5.534792209580451 0.11269661754352578 DSPAFPDS(ph)PWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DSPAFPDSPWR 11 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 DSPAFPDS(1)PWR;DSPAFPDS(1)PWR;DSPAFPDS(1)PWR;DSPAFPDS(1)PWR 124.38 0.00051456 11495600.0 63975.0 101924.0 89623.0 71962.0 93120.0 61183.0 87515.0 53169.6 62623.0 58157.0 True False 74804.70393615362 112042.34112775052 91759.95221712014 67930.20244395196 74873.80446751314 57974.45577348413 79224.94564626856 51773.95433784792 63538.74290392352 68700.40372944128 1.088853920433314 1.6308832997401328 1.3356537550855292 0.9887889845811887 1.0898597446731781 0.8438735819050129 1.1531947608092008 0.7536193606917684 0.9248670961840978 1.0 16.068030956857037 -5.750544986305952 4.323904553142578 0.9595857537542145 1.3885572535990958 0.5448722718728596 0.1618301460395632 0.13647386668977055 5.9744079184300425 0.0436970075822984 0.07348250830289552 1.7760492870540695e-06 5.750544986305952 0.42897149984488125 DSPAFPDS(ph)PWR ddPTM_PC-9_Lapatinib_30min_R1 4 DSPAFPDSPWR 11 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 DSPAFPDS(1)PWR;DSPAFPDS(1)PWR;DSPAFPDS(1)PWR;DSPAFPDS(1)PWR 129.76 0.00024321 12763200.0 47382.8 69275.0 57793.8 55588.4 63213.8 60207.2 55609.8 65459.4 64317.6 43850.9 True False 46707.11258305866 69114.59799374323 53042.216854519516 59676.55637346637 59495.68856711252 57632.27840583812 58489.00334315885 68500.8826952884 57073.4745936462 51430.46963734855 0.9081603359332381 1.3438453601744393 1.0313383725355003 1.1603346575340145 1.156817913323254 1.1205862752609563 1.1372442008712367 1.3319124475881394 1.1097210466108542 1.0 15.650335707270157 DSPAFPDS(ph)PWRER ddPTM_PC-9_AZD4547_30min_R2 3 DSPAFPDSPWRER 13 1 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 DSPAFPDS(1)PWRER;DSPAFPDS(1)PWRER;DSPAFPDS(1)PWRER 116.78 0.00012682 17856500.0 34628.0 18091.100000000002 45630.0 101616.0 79580.0 45005.0 32821.0 50064.0 31475.3 60485.0 True False 45638.98369285555 23938.694284257534 45024.91638588764 78190.00115154994 68531.6906507899 42190.830235475594 35742.00541729811 42327.75915627129 33139.020099901514 58367.43856020115 0.78192541627097 0.4101378246976996 0.7714046992048176 1.3396167980012257 1.1741425072149632 0.7228487539668075 0.6123620686289533 0.7251947352908716 0.5677655370420508 1.0 15.832876136863666 -6.966403245412854 24.991410530610043 0.6983118945028001 0.8924916682634376 0.09520244986733128 0.25592350057071656 470.84401426819915 350242.520389048 0.10106022804257818 0.08912629283401498 1.0804302984591121e-07 6.966403245412854 0.19417977376063755 DSPAFPDS(ph)PWRER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DSPAFPDSPWRER 13 1 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 DSPAFPDS(1)PWRER;DSPAFPDS(1)PWRER;DSPAFPDS(1)PWRER;DSPAFPDS(1)PWRER 105.17 0.00059375 17249700.0 32935.399999999994 18689.6 39773.5 51096.0 58430.1 57906.5 43827.6 61107.600000000006 53903.0 39646.4 True False 38510.71271619841 20544.979972736597 40721.851081838715 48233.2567754671 46981.14134898241 54869.78120143276 39675.93244365417 59503.590248854125 54691.22940054277 46833.9784792703 0.8222814709889329 0.4386768034629011 0.8694937394623234 1.0298774168164286 1.0031422243954193 1.1715806126895514 0.8471612647901687 1.2705217916772042 1.1677681712381163 1.0 15.51526797766577 -5.565952177548663 3.0721560599097026 1.0745231243178768 0.628996721858324 0.6061244317527208 0.14094058921689034 0.1533053609856731 2.9379411359021863 0.038356835708256924 0.07819416889846781 2.716738406734634e-06 5.565952177548663 -0.4455264024595528 DSPAFPDS(ph)PWRER ddPTM_PC-9_Lapatinib_30min_R1 4 DSPAFPDSPWRER 13 1 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 DSPAFPDS(1)PWRER;DSPAFPDS(1)PWRER;DSPAFPDS(1)PWRER;DSPAFPDS(1)PWRER 92.8 0.002094 12646900.0 56580.0 30946.699999999997 61029.0 43831.3 41648.0 44603.3 28767.7 27848.6 50575.0 27950.5 True False 55773.15882449878 30875.044817509577 56011.43119875265 47054.80001893047 39198.34652311843 42695.72083437067 30257.15074456284 29142.547622312606 44878.71092163974 32781.70668329982 1.701350065855834 0.9418376265698953 1.7086185212951983 1.4353981161969789 1.1957384312479216 1.3024251985062576 0.9229888802579314 0.8889881147389702 1.3690169140736828 1.0 15.000603345623114 -6.768847207015619 1.616755720779031 1.0466711811328138 1.4200051693748874 0.3260003237197706 0.24116193867362423 0.45652050251072995 2.474960724189947 0.10224884598415211 0.09245038539971415 1.7027574651967106e-07 6.768847207015619 0.37333398824207364 DSPLQGSGQQNS(ph)QAGQRNSTSSIEPR ddPTM_PC-9_Lapatinib_30min_R1 1 DSPLQGSGQQNSQAGQRNSTSSIEPR 26 1 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6 C9J840;O95819-6 MAP4K4 1 DSPLQGS(0.218)GQQNS(0.574)QAGQRNS(0.171)T(0.028)S(0.007)S(0.002)IEPR 63.63 0.00036586 9274700.0 6805.1 2146.6 3620.0 2248.6 1302.0 1894.7 1199.2 2047.9 5760.8 2072.9 True False 6708.058026097504 2141.6296795867115 3322.377573604099 2413.9695451097064 1225.4189198304878 1813.6680977614226 1261.288708269336 2143.052910226509 5111.958040086646 2431.19800303437 2.7591574268016017 0.8808948003880189 1.366559848049172 0.9929135932560159 0.5040391273360074 0.7459976914664251 0.5187930833667705 0.8814802034025087 2.10264981861059 1.0 11.247451679617823 -8.225787299530378 24.964944855822342 1.5513262241887487 1.0319568200897746 0.07097640928256199 0.6613542069006887 1288.7448094450413 902430.7414632373 0.44487875236889396 0.16813611449092333 5.945832909830495e-09 8.225787299530378 -0.519369404098974 DSPLQGSGQQNSQAGQRNS(ph)TSSIEPR ddPTM_PC-9_AZD4547_30min_R2 2 DSPLQGSGQQNSQAGQRNSTSSIEPR 26 1 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6 C9J840;O95819-6 MAP4K4 1 DSPLQGS(0.002)GQQNS(0.081)QAGQRNS(0.835)T(0.051)S(0.015)S(0.015)IEPR;DSPLQGSGQQNS(0.002)QAGQRNS(0.847)T(0.095)S(0.039)S(0.017)IEPR 68.303 0.00016698 20436100.0 8464.3 2361.2 10844.099999999999 24447.0 21329.0 10576.900000000001 6613.1 13381.2 8151.0 15993.8 True False 11155.771331622893 3124.411724217371 10700.300148590935 18811.12185238485 18367.836515339226 9915.524770972152 7201.653088727764 11313.443009385928 8581.84521940369 15433.86193013384 0.7228113988658801 0.20243875048001525 0.6933002379462224 1.2188214419397572 1.190099833631202 0.6424526029750588 0.46661380808823344 0.7330273563803884 0.5560400409341533 1.0 13.91381148425268 -5.512351801123923 24.80704018812493 0.8217492410783565 0.4589361169451253 0.2329004940367756 0.26406141336390254 676.7277576559574 1594725.2356027386 0.0766916956954568 0.1447773942755336 3.073606025261731e-06 5.512351801123923 -0.36281312413323114 DSPLQGSGQQNSQAGQRNS(ph)TSSIEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DSPLQGSGQQNSQAGQRNSTSSIEPR 26 1 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6 C9J840;O95819-6 MAP4K4 1 DSPLQGS(0.03)GQQNS(0.077)QAGQRNS(0.364)T(0.364)S(0.123)S(0.043)IEPR;DSPLQGS(0.001)GQQNS(0.008)QAGQRNS(0.537)T(0.151)S(0.216)S(0.088)IEPR 67.418 0.00018627 16404000.0 5605.8 988.12 6351.700000000001 9226.6 7706.7 14909.4 8008.1 11201.8 10027.900000000001 7905.099999999999 True False 6554.751220403127 1086.2140233424204 6503.1486169563905 8709.663515040795 6196.627458008849 14127.524817501337 7249.514794376759 10907.764619288171 10174.539066577048 9338.232053262835 0.7019263585458725 0.11631902239598883 0.6964004085424447 0.9326887001054537 0.6635760840665456 1.512869324399054 0.7763262631542482 1.1680759866614079 1.0895573175462054 1.0 13.188933724380746 -5.809764607626908 1.3288365566853988 1.0698881445862107 0.3976349692838235 0.48558457253198706 0.25345580626110664 0.36022404660243706 1.2773426293823495 0.08390926259044006 0.1944018996696819 1.549656322052943e-06 5.809764607626908 -0.6722531753023873 DSPLQGSGQQNSQAGQRNS(ph)TSSIEPR ddPTM_PC-9_Lapatinib_30min_R1 1 DSPLQGSGQQNSQAGQRNSTSSIEPR 26 1 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6 C9J840;O95819-6 MAP4K4 1 DS(0.001)PLQGS(0.168)GQQNS(0.077)QAGQRNS(0.421)T(0.184)S(0.084)S(0.065)IEPR 46.43 0.017634999999999998 5249200.0 8672.8 4135.1 4986.1 5433.9 3462.2 3609.9 2703.9 984.06 5681.1 3927.5 True False 8549.124281603272 4125.525430009789 4576.162104902597 5833.527132959009 3258.560202947094 3455.51299208791 2843.8947117156927 1029.78302008765 5041.234693364856 4606.363141935208 1.8559379749664389 0.8956144582809832 0.9934436265439718 1.2664062630781319 0.7074041065677076 0.750160785334044 0.6173839586865326 0.22355662989588385 1.0944067017796932 1.0 12.169412434919552 -1.5228787452824777 0.6095635405222785 0.719228143936119 68.17748434145348 0.5250569553554726 0.28291396612648656 144.01265042807137 1.0786441187384688 0.12741071362582782 12975.291486618726 0.029999999999852166 1.5228787452824777 67.45825619751736 DSPPT(ph)PTMYK ddPTM_PC-9_AZD4547_30min_R2 1 DSPPTPTMYK 10 0 Q9C0B5;Q9C0B5-2;H0YEF4 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5;Palmitoyltransferase 1 DS(0.055)PPT(0.943)PT(0.002)MYK 89.266 0.036134 4224100.0 16955.0 29945.0 33106.0 45615.0 41855.0 33948.0 53413.0 67638.0 46798.0 39882.0 True False 22346.337314091666 39624.13564360887 32666.99280892387 35099.16649472473 36044.15571988954 31825.226193399063 58166.65352530826 57186.10126661634 49271.64673998948 38485.74331913604 0.5806393585486637 1.029579585225441 0.8488076360650947 0.9120043805227109 0.9365586477309252 0.826935468791499 1.5113818393209102 1.4859035147745745 1.280257115769164 1.0 15.232036491540613 -7.253586525418974 24.975970975380996 1.3598775802717393 0.8695693225041609 0.6348404352919785 0.17097023727836283 341.1552328403959 1085044.8332588885 0.06294924271201159 0.04784669304187427 5.577164760246479e-08 7.253586525418974 -0.49030825776757847 DSPPT(ph)PTMYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSPPTPTMYK 10 0 Q9C0B5;Q9C0B5-2;H0YEF4 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5;Palmitoyltransferase 1 DS(0.005)PPT(0.992)PT(0.003)MYK 88.155 0.038845 5069000.0 27497.0 32543.0 52889.0 34191.0 95301.0 37087.0 40764.0 37060.0 41110.0 34617.0 True False 32151.699009494587 35773.653970805535 54150.07434264943 32275.38911871762 76627.45317395276 35142.092432067846 36902.53881419739 36087.21426831577 41711.15597752098 40892.788071978764 0.7862437492132288 0.874815723198853 1.3241961943836018 0.7892684906176377 1.8738622820012778 0.8593713974750598 0.9024216873949067 0.8824835862205261 1.020012524069079 1.0 15.319558808774518 DSPS(ph)VWAAVPGK ddPTM_PC-9_AZD4547_30min_R2 2 DSPSVWAAVPGK 12 0 P07737;I3L3D5;CON__P02584 P07737 PFN1 Profilin-1 1 DS(0.232)PS(0.768)VWAAVPGK;DS(0.27)PS(0.73)VWAAVPGK 170.95 0.0010825 54579000.0 92808.0 133336.0 124849.0 122885.0 106927.0 140923.0 99952.0 136330.0 116190.0 104324.0 True False 122319.01347367854 176434.25447240722 123193.42068511245 94555.76180432425 92082.03174437066 132111.0625324724 108847.53436731898 115263.33105174288 122331.56619341367 100671.64851375438 1.2150294077777675 1.7525714247969397 1.2237151422853774 0.9392491649861626 0.9146769036149224 1.3122966046833193 1.081213390008683 1.144943315753838 1.215154097498463 1.0 16.619297918381072 -5.509910746258786 23.384464184188758 1.0937959246003683 1.4848862831061052 0.4736141032489838 0.16567703444562365 201.99359978999325 364241.7607237175 0.04275002328246298 0.08270588622270227 3.0909305977868566e-06 5.509910746258786 0.3910903585057368 DSPS(ph)VWAAVPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DSPSVWAAVPGK 12 0 P07737;I3L3D5;CON__P02584 P07737 PFN1 Profilin-1 1 DS(0.048)PS(0.952)VWAAVPGK;DS(0.011)PS(0.989)VWAAVPGK;DS(0.05)PS(0.95)VWAAVPGK;DS(0.226)PS(0.774)VWAAVPGK 151.16 0.00018407 56051900.0 127669.0 167398.0 145228.0 126685.0 152653.0 110815.0 149172.0 102174.0 104216.0 92831.0 True False 149280.84012230998 184016.16714515898 148690.78630025696 119587.25016831163 122741.74047872938 105003.66632134157 135041.34824824482 99492.0407623015 105739.96184269822 109660.52545020853 1.3612996974931613 1.6780529401047937 1.3559189661896174 1.0905223158228468 1.1192882760210774 0.9575338608879691 1.2314490350455276 0.9072730625157908 0.9642481778067856 1.0 16.742684766029264 -5.677729690881469 2.7028514413703246 1.0363783839192995 1.5235823518888656 0.7584186916072306 0.112857438336171 0.12024849271443988 1.7716728773267738 0.03161439767989392 0.06072007303759068 2.1002466909077106e-06 5.677729690881469 0.4872039679695661 DSPS(ph)VWAAVPGK ddPTM_PC-9_Lapatinib_30min_R1 1 DSPSVWAAVPGK 12 0 P07737;I3L3D5;CON__P02584 P07737 PFN1 Profilin-1 1 DS(0.314)PS(0.686)VWAAVPGK 96.745 0.0041878 63358000.0 21972.0 40000.0 40192.0 31084.0 41672.0 33910.0 40398.0 44151.0 32608.0 32941.0 True False 21658.675250828677 39907.382457592656 36887.56890560664 33370.02105318426 39220.934890304234 32459.748348070858 42489.610771067906 46202.416641149786 28935.3436625374 38634.807958876525 0.5606000494135366 1.03293854857699 0.954775521205394 0.8637294402680561 1.0151709549598795 0.8401684921695872 1.0997753843190963 1.1958754056789498 0.7489449331115252 1.0 15.237613606350571 -4.756621485945085 24.999977463664706 0.9757384878361237 0.560599418775099 0.5007229502649215 0.12331295701048742 123.48721825827515 640698.2105417113 0.03008679549264412 0.2397215503668826 1.7513724512409322e-05 4.756621485945085 -0.4151390690610247 DSPSKSS(ph)AEAQTPEDTPNK ddPTM_PC-9_Lapatinib_30min_R1 1 DSPSKSSAEAQTPEDTPNK 19 1 A0A5F9UY30;A0A5H1ZRP2;O43493;O43493-5;O43493-3;O43493-7;O43493-4 A0A5F9UY30 TGOLN2 Trans-Golgi network integral membrane protein 2 1 DS(0.019)PS(0.152)KS(0.152)S(0.676)AEAQTPEDTPNK 67.994 0.0041348999999999995 7041600.0 17660.0 22848.0 48477.0 18603.0 24499.0 20925.0 21272.0 20516.0 37828.0 19474.0 True False 17408.165161552646 22795.096859776924 44491.40818663146 19971.126677788787 23058.016986887214 20030.086528557433 22373.36007530463 21469.248257340234 33567.41229350052 22840.05495252608 0.7621770261821251 0.9980316118834827 1.947955391486953 0.8743904828293773 1.0095429732903085 0.8769719061618165 0.9795668233639765 0.9399823381320614 1.4696730092493937 1.0 14.479278501337836 -4.994533249598646 22.86157488852714 1.1306895950309352 0.8211394012908513 0.11414532833843083 0.31738544761393805 127.86643195385848 534635.9003538328 0.08044035718203098 0.30622408572207205 1.0126672160139806e-05 4.994533249598646 -0.30955019374008397 DSPSVWAAVPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSPSVWAAVPGK 12 0 P07737;I3L3D5;CON__P02584 P07737 PFN1 Profilin-1 0 140.17 0.00034381 12439000.0 50365.0 62568.0 58317.0 69448.0 68223.0 54287.0 58416.0 49039.0 51585.0 54407.0 False True 58890.79974590663 68779.33754249346 59707.498448454084 65557.0537134539 54855.192892903266 51440.09415319837 52882.41358478453 47751.77821111541 52339.33303576791 64270.55841442496 0.9162951310640723 1.0701531033695912 0.9290023289272256 1.0200168682327833 0.8535042210025594 0.8003679355250957 0.8228093063046351 0.7429806024588382 0.814359394518981 1.0 15.971870386827074 -6.370128265356138 4.462191233762083 0.8200245418589815 0.9858118401278975 0.46949151228186836 0.07442326494652832 0.1749393901248775 5.723383049941752 0.02217627861186402 0.025302357572366697 4.264535506000516e-07 6.370128265356138 0.16578729826891592 DSQDAGGFGPEDR ddPTM_PC-9_AZD4547_30min_R2 2 DSQDAGGFGPEDR 13 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 140.91 6.0354e-05 7465200.0 36864.0 34412.0 45706.0 63775.0 49938.0 44068.0 42817.0 55217.0 45359.0 43144.0 False True 48585.98518116632 45535.006036662795 45099.9085762301 49072.65906392785 43004.970692625575 41312.42099359937 46627.63005248022 46684.48141043129 47756.58413776616 41633.54169201157 1.16699140180257 1.093709643381116 1.0832589960724777 1.1786808681074485 1.0329404836792242 0.9922869713850501 1.119953483597743 1.1213190017746886 1.1470699392103232 1.0 15.345458670772326 -8.486884111018986 0.00925499715322107 1.619476395785907e-05 2.151705362809427 0.17725816060943522 0.05719369189911565 3824.3722179046927 24.196451700237876 2843.6159780454773 2778.285377829557 3.2592366025066395e-09 8.486884111018986 2.1516891680454693 DSQDAGGFGPEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSQDAGGFGPEDR 13 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 122.39 0.00084111 6405400.0 11096.0 12409.0 21378.0 13703.0 21738.0 14831.0 16203.0 12861.0 15596.0 13504.0 False True 12974.333644010332 13640.883511775995 21887.732596516475 12935.265335725411 17478.594947538688 14053.236251516659 14668.13454043864 12523.412377355888 15824.061995266771 15952.168302394823 0.8133272792804322 0.8551115593312888 1.3720851097860203 0.8108781885020296 1.0956877219578174 0.8809608816255351 0.9195072583478562 0.7850601962039109 0.9919693483230854 1.0 13.961464915545983 -6.810928251891754 24.998937831734974 0.9023161732726823 0.9932976824616587 0.04484848895589477 0.16456175122421884 343.5588022676475 173543.59079190055 0.057545258933889815 0.050750223303790365 1.5455097461242574e-07 6.810928251891754 0.0909815091889764 DSQDAGGFGPEDR ddPTM_PC-9_Lapatinib_30min_R1 2 DSQDAGGFGPEDR 13 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 141.38 5.3961999999999996e-05 9927600.0 59878.0 57681.0 59377.0 46861.0 49048.0 55906.0 39791.0 41995.0 60978.0 36515.0 False True 59024.128739719636 57547.4431884101 54495.25226184821 50307.31426371343 46163.09307207816 53515.03070325122 41851.18328114171 43946.241010284815 54110.01551319325 42826.56909682088 1.3782128707597345 1.343732276529291 1.2724636460755743 1.1746753318011613 1.0779078045620274 1.249575481572344 0.9772247500500437 1.026144329024644 1.2634683714883423 1.0 15.386218484860054 -5.571684862586988 0.8763232562341147 1.0881047713985497 1.4181838928390755 0.5882315567194081 0.08936822525116908 0.651487230628506 0.8090853772793243 0.03664718232046566 0.16596145047759628 2.6811131171464805e-06 5.571684862586988 0.33007912144052587 DSQDAS(ph)AEQSDHDDEVASLASASGGFGTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DSQDASAEQSDHDDEVASLASASGGFGTK 29 0 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 DS(0.005)QDAS(0.66)AEQS(0.335)DHDDEVASLASASGGFGTK;DS(0.02)QDAS(0.545)AEQS(0.435)DHDDEVASLASASGGFGTK;DS(0.005)QDAS(0.669)AEQS(0.325)DHDDEVASLASASGGFGTK 83.82600000000001 7.4463e-08 47901300.0 134333.0 135985.0 155391.0 163806.0 188262.0 183693.0 179548.0 163884.0 167161.0 135496.0 True False 157072.92370231063 149484.69210644334 159096.11076364887 154628.48088621718 151373.4125500752 174059.81570695507 162539.91362504967 159582.21864945145 169605.41338745772 160060.35221425456 0.9813356120324851 0.9339270471324792 0.9939757632838708 0.9660636050533842 0.9457270989098466 1.0874636554214314 1.015491415434823 0.9970127919988387 1.0596341382557142 1.0 17.288256463442636 -6.738677963041687 24.999999880531274 1.0307069132712963 0.9642807549219633 0.5652968848120901 0.029680414286495614 176.97152372027088 194376.2330394876 0.009549973029458208 0.009543438957192943 1.82524865445721e-07 6.738677963041687 -0.06642615834933296 DSQDAS(ph)AEQSDHDDEVASLASASGGFGTK ddPTM_PC-9_Lapatinib_30min_R1 3 DSQDASAEQSDHDDEVASLASASGGFGTK 29 0 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 DS(0.002)QDAS(0.882)AEQS(0.115)DHDDEVASLASASGGFGTK;DS(0.003)QDAS(0.631)AEQS(0.366)DHDDEVASLASASGGFGTK;DS(0.219)QDAS(0.441)AEQS(0.34)DHDDEVASLASASGGFGTK 98.147 6.094e-11 53933000.0 77334.0 77498.3 79461.6 61677.5 83365.8 73854.4 67764.3 65991.1 83688.0 53536.2 True False 76231.20297868125 77318.85744783127 72928.57397864634 66213.46910010852 78462.38754746901 70695.8194750151 71272.80388073366 69057.2874183549 74262.17616629145 62789.8608374975 1.2140686722649447 1.231390807632706 1.1614705464531638 1.0545248582644806 1.2496028260125085 1.1259113897063495 1.1351005230795197 1.0998159017596445 1.1827096791707299 1.0 15.938243994392103 -14.522878744803894 0.10352863915051626 0.5101767043929804 1.2578487669006329 0.46296178935262833 0.05512389531130447 167.74391349583908 1.1678828160019132 17.76016654480039 0.8428348787103306 3.0000000032911583e-15 14.522878744803894 0.7476720625076525 DSQDASAEQS(ph)DHDDEVASLASASGGFGTK ddPTM_PC-9_AZD4547_30min_R2 5 DSQDASAEQSDHDDEVASLASASGGFGTK 29 0 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 DSQDAS(0.131)AEQS(0.867)DHDDEVAS(0.001)LASASGGFGTK;DS(0.166)QDAS(0.412)AEQS(0.421)DHDDEVAS(0.001)LASASGGFGTK;DS(0.001)QDAS(0.141)AEQS(0.859)DHDDEVASLASASGGFGTK;DSQDAS(0.034)AEQS(0.965)DHDDEVASLASASGGFGTK;DS(0.004)QDAS(0.169)AEQS(0.827)DHDDEVASLASASGGFGTK 93.384 1.8214e-09 150223700.0 175941.0 165308.0 220655.0 331645.0 279233.0 252705.0 221029.0 280568.0 227429.0 241458.0 True False 231886.57819985892 218740.5782258706 217728.97052658442 255189.36911417235 240466.31786242806 236903.31640164152 240700.15281009057 237212.66241124796 239450.4326344941 233004.62891409555 0.9952015944084578 0.9387821145240688 0.934440536830953 1.0952115857245732 1.0320237798841476 1.0167322319119392 1.0330273434131312 1.0180598708135702 1.0276638440636945 1.0 17.82999909045403 -5.739587172774945 24.99999418387366 1.0319999818436782 0.954405459726516 0.6071937811730823 0.027881931879581358 155.42564911668586 177813.1519810643 0.007515486102174401 0.013003299130711956 1.8214314337033182e-06 5.739587172774945 -0.07759452211716222 DSQDASAEQS(ph)DHDDEVASLASASGGFGTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DSQDASAEQSDHDDEVASLASASGGFGTK 29 0 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 DS(0.004)QDAS(0.362)AEQS(0.634)DHDDEVASLASASGGFGTK;DSQDAS(0.043)AEQS(0.957)DHDDEVASLASASGGFGTK 98.26100000000001 6.0102e-11 38711000.0 103456.0 130831.0 135996.0 152286.0 163619.0 155662.0 166457.0 149012.0 135544.0 120448.0 True False 120969.05745085927 143819.0370480431 139238.66040770194 143753.90913787374 131559.03149881918 147498.81069271025 150688.98791568202 145100.5928912647 137526.07457594515 142284.26893415675 0.8501927750483698 1.0107866324603783 0.9785949033630402 1.0103289015344141 0.9246210595473435 1.0366487581347912 1.0590699101487786 1.0197936425312852 0.966558535290971 1.0 17.118416639567336 -6.774951779670193 24.999282995888173 1.020317261896754 0.9624046213650296 0.275028424579267 0.0489799295899599 341.68115100226896 632139.9219841508 0.017144155634864267 0.015203943182034784 1.6789904284526686e-07 6.774951779670193 -0.0579126405317244 DSQDASAEQS(ph)DHDDEVASLASASGGFGTK ddPTM_PC-9_Lapatinib_30min_R1 3 DSQDASAEQSDHDDEVASLASASGGFGTK 29 0 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 DS(0.017)QDAS(0.222)AEQS(0.761)DHDDEVASLASASGGFGTK;DS(0.014)QDAS(0.385)AEQS(0.601)DHDDEVASLASASGGFGTK;DS(0.005)QDAS(0.092)AEQS(0.903)DHDDEVASLASASGGFGTK 87.79700000000001 2.2376e-08 86801000.0 194394.0 191807.0 216104.0 181285.0 206245.0 212582.0 167638.0 186438.0 222315.0 147291.0 True False 191621.90591250642 191362.88267608723 198336.76330556342 194617.30364903237 194114.0745932711 203490.36341284568 176317.47538096618 195100.59010538115 197275.54361926526 172750.05309707948 1.109243687495839 1.1077442770367658 1.1481140511957186 1.1265831770231889 1.1236701298388938 1.1779467488701216 1.0206507738778057 1.1293807822782054 1.141970957938886 1.0 17.398326628482366 -11.239304882376388 2.5030983792205657 0.9765360420263915 1.1202942277582408 0.4674467935424891 0.03861293056797172 7212181.5326451305 5507299.951830623 1059704.7693372592 0.009584252670312408 5.763617052655061e-12 11.239304882376388 0.1437581857318493 DSQDGSSYR ddPTM_PC-9_AZD4547_30min_R2 1 DSQDGSSYR 9 0 Q14847;Q14847-2;C9J9W2;Q14847-3;J3KSN1 Q14847 LASP1 LIM and SH3 domain protein 1 0 128.6 0.0061042 19098000.0 45946.0 33400.0 47309.0 72568.0 71967.0 57302.0 52075.0 58700.0 48708.0 53036.0 False True 60555.87226383108 44195.896827401426 46681.651748848504 55838.56876442369 61975.6242908443 53718.89688152924 56709.57411735775 49629.263791809 51282.6054406472 51179.22578290201 1.1832119641806231 0.8635514928435362 0.9121211005978903 1.0910397316537421 1.210952751683656 1.04962308553475 1.108058460241564 0.9697150168377338 1.0020199535292644 1.0 15.643270702627937 -4.446266629343988 20.146293283846116 1.0296915796458546 6.550410185411348 0.2017037696364935 0.09477746887547342 288.3029405056506 76109.35138683947 0.02500320342761104 279.7557447916242 3.578766560115922e-05 4.446266629343988 5.520718605765493 DSQDGSSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSQDGSSYR 9 0 Q14847;Q14847-2;C9J9W2;Q14847-3;J3KSN1 Q14847 LASP1 LIM and SH3 domain protein 1 0 111.06 0.010414 12519000.0 18342.0 23825.0 22880.0 24236.0 34662.0 30255.0 31578.0 21482.0 26427.0 21002.0 False True 21446.938328986795 26190.18854606036 23425.545972883214 22878.13549417214 27870.229923248957 28668.374539116474 28586.703235078156 20918.12026206044 26813.444880027884 24809.496348259487 0.8644648818310818 1.0556517624710964 0.9442169096885611 0.9221523554135818 1.1233694361233655 1.1555403679578407 1.1522484307539624 0.8431497346187745 1.0807734467333912 1.0 14.59860482726493 -6.251074966465749 24.651612736196913 1.060809140142297 0.9542375971526309 0.24648892444541004 0.09601809164807597 978.6672345983324 2327744.4320739545 0.029833460062327517 0.03807386719893544 5.609511381592523e-07 6.251074966465749 -0.10657154298966609 DSQDGSSYR ddPTM_PC-9_Lapatinib_30min_R1 2 DSQDGSSYR 9 0 Q14847;Q14847-2;C9J9W2;Q14847-3;J3KSN1 Q14847 LASP1 LIM and SH3 domain protein 1 0 ; 117.01 0.0086791 25330000.0 65108.0 62494.0 68123.0 56490.0 72562.0 60164.0 64705.0 59656.0 72759.0 45388.0 False True 64179.54798065508 62349.29898261991 62522.189902384554 60644.463045115765 68294.04582238085 57590.92596913402 68055.10829600356 62427.83554493512 64564.115233763376 53233.25532429159 1.2056288421528947 1.1712471574919532 1.174494956611346 1.1392213885037812 1.2829207119936674 1.081859931696755 1.2784322108692912 1.1727224864350505 1.2128530340751347 1.0 15.70004017231314 -10.471545386924838 5.316466140316423 0.9999995110173395 1.189971794209081 0.5034668388649031 0.056907734586399125 3.0203218783393316e-07 5.968760258034234e-08 0.050463051102927974 0.01223905608978735 3.3764056090943245e-11 10.471545386924838 0.18997228319174153 DSQS(ph)ASGEERPPEADGK ddPTM_PC-9_AZD4547_30min_R2 1 DSQSASGEERPPEADGK 17 1 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 DS(0.218)QS(0.391)AS(0.391)GEERPPEADGK 48.896 0.043071 6518000.0 14508.0 18529.0 14050.0 16072.0 15036.0 27970.0 15743.0 22826.0 20280.0 14714.0 True False 19121.242214853544 24518.13689565632 13863.687819893075 12366.848709924709 12948.510940252268 26221.031478419114 17144.09650176788 19298.76618929868 21351.959397559436 14198.867338593045 1.3466737704409213 1.7267670942325886 0.9763939256063799 0.8709743118953691 0.911939708391932 1.8466988142884737 1.2074270498442923 1.3591764560574435 1.5037790612723048 1.0 13.793488228281548 -6.716404984179569 24.99999393138933 1.3948716877649676 1.1706883807183788 0.11023117889837764 0.30709407145346657 323.28698066223564 179465.56942690743 0.10690529769462355 0.10690484541442143 1.9212992614908803e-07 6.716404984179569 -0.22418330704658884 DSREEVER ddPTM_PC-9_AZD4547_30min_R2 1 DSREEVER 8 1 A2AB27;P36915 A2AB27 GNL1 Guanine nucleotide-binding protein-like 1 0 77.318 0.030737 1976400.0 5468.3 2223.6 7149.0 15115.0 9718.4 7535.7 6051.9 6280.6 6769.8 7485.9 False True 7207.105652294156 2942.335215132031 7054.199588926378 11630.470274422103 8369.167911794873 7064.491487734106 6590.507375916225 5310.077583830244 7127.637807179379 7223.820919530626 0.9976860905852084 0.40731009917161837 0.976519167280898 1.6100164170705664 1.1585514099841039 0.9779438840509251 0.9123298389219273 0.7350787959698302 0.9866852856095584 1.0 12.8185464131249 -10.765656288540212 14.231650756702447 0.9999237058804856 0.9724738993642305 0.0007517771671627926 0.2865925810001129 0.0 0.0 0.3035450986592374 0.07362050023003351 1.715314312884094e-11 10.765656288540212 -0.02744980651625517 DSREEVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSREEVER 8 1 A2AB27;P36915 A2AB27 GNL1 Guanine nucleotide-binding protein-like 1 0 79.71300000000001 0.026345 1785800.0 5340.5 2981.0 5857.4 6857.6 7661.4 8158.6 6147.5 8302.6 8355.7 4519.3 False True 6244.5411703169775 3276.933979257333 5997.062630313199 6473.390904639168 6160.203667820082 7730.748653605542 5565.1642959542405 8084.665547331862 8477.886305068652 5338.613315240883 1.169693476860333 0.6138174439235397 1.1233371432226698 1.2125603639729212 1.1538958347542592 1.4480817765046772 1.04243629709359 1.514375563454173 1.5880315363665036 1.0 12.382249340615711 -5.61987590203786 2.6052758692695983 1.2990565971592416 0.8870220124235664 0.3149955090333991 0.22310823537929209 0.2955972557371689 4.031904760816398 0.06268515164193321 0.12827234889979433 2.399518474155793e-06 5.61987590203786 -0.4120345847356752 DSS(ph)EPRDEGGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSSEPRDEGGGR 12 1 K7EQ21;Q9P0U4;Q9P0U4-2;K7EJR0;K7EQZ1;A0A669KB29 K7EQ21;K7EQZ1 CXXC1 CXXC-type zinc finger protein 1 1 DS(0.11)S(0.89)EPRDEGGGR 88.163 0.039501999999999995 538820.0 2953.7 1001.0 3519.9 3570.5 3448.0 2848.5 2842.5 2633.5 2425.9 2272.7 True False 3453.703071765801 1100.3726646214652 3603.8277652950846 3370.456460717185 2772.389151675104 2699.119645502339 2573.2378220821342 2564.373415423898 2461.374198148094 2684.7225193166987 1.2864283168618926 0.4098645788174512 1.3423464582895932 1.255420787983339 1.032653889453245 1.005362612367592 0.9584744060391988 0.9551726098221014 0.9168076702297524 1.0 11.390557270193947 -7.002626264378735 2.638889845378201 0.9541194127163921 1.054278307680599 0.04081004596616189 0.24422783744218018 1.2975596093371113 18.19792766955784 0.10166560775470763 0.08126444215259519 9.939710502877058e-08 7.002626264378735 0.10015889496420693 DSS(ph)PSSSPSPK ddPTM_PC-9_AZD4547_30min_R2 2 DSSPSSSPSPK 11 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 DS(0.017)S(0.881)PS(0.069)S(0.017)S(0.017)PSPK;DS(0.002)S(0.871)PS(0.05)S(0.015)S(0.036)PS(0.026)PK 122.7 0.0017387999999999998 0.0 47199.0 41504.0 38041.0 33599.0 34164.0 38319.0 36662.0 39991.0 40415.0 33452.0 True False 62207.30019981202 54919.35634504396 37536.55148445214 25853.269649375346 29420.91831356603 35922.9068724184 39924.84697629513 33811.30985175864 42551.25439114221 32280.855661996335 1.9270647857407184 1.7012980362134429 1.162811539987871 0.8008855130755388 0.9114045371542845 1.112823874576218 1.2367964280233725 1.0474105830956668 1.3181575741573985 1.0 14.978391199892462 -5.211064031371302 3.003120972478522 1.0603501964836441 1.8859810303397593 0.8199870007853213 0.14105634603609005 0.10942895696080261 1.9307757748683334 0.04070722224715116 0.13184939180393568 6.150861791443122e-06 5.211064031371302 0.8256308338561151 DSS(ph)SLSSCTSGILEER ddPTM_PC-9_AZD4547_30min_R2 1 DSSSLSSCTSGILEER 16 0 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 DS(0.003)S(0.929)S(0.068)LSSCTSGILEER 152.34 1.5016e-10 0.0 8623.0 9298.4 11840.0 15223.0 12995.0 14639.0 12965.0 13730.0 10237.0 11318.0 True False 11364.934630457827 12303.925959877519 11682.993863881435 11713.572543005466 11190.868560027824 13723.621015823297 14118.859883466985 11608.343984012565 10778.106920750286 10921.760264931085 1.040577192208635 1.126551550429509 1.0696988013365036 1.0724985953607522 1.02463964494449 1.2565393016260178 1.2927275037158192 1.0628638335237999 0.9868470520597253 1.0 13.414917774344532 -7.998546795178094 24.999887291218197 1.0039007928937014 1.1269720331022992 0.29100246151559317 0.08291703134690899 64.35486902002197 1107127.560444108 0.05069455728589697 0.02406908653487134 1.0033517322949002e-08 7.998546795178094 0.12307124020859783 DSS(ph)SLSSCTSGILEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSSSLSSCTSGILEER 16 0 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 DS(0.004)S(0.671)S(0.325)LSSCTSGILEER 140.93 2.2341999999999997e-05 2641000.0 8204.6 6280.1 10144.0 10867.0 11621.0 9297.0 11382.0 12078.0 7216.2 7049.0 True False 9593.476731763443 6903.546824265003 10385.871431334232 10258.15722128935 9343.948472046513 8809.448953566876 10303.814561456065 11760.965297698809 7321.723273290854 8326.927900146706 1.152102773892689 0.8290628797378412 1.247263283155274 1.231925788754412 1.122136348974739 1.0579470675387581 1.237408884166576 1.412401480922106 0.87928265515087 1.0 13.023568616903187 -5.278569993254484 24.90587708227945 1.165247002015569 0.9905827874206425 0.13006750870589956 0.1587755664570559 1179.0209331485719 1714156.0017928681 0.03986897486888672 0.08333702681598439 5.265383482789437e-06 5.278569993254484 -0.17466421459492643 DSS(ph)STDSANEKPALIPR ddPTM_PC-9_Lapatinib_30min_R1 1 DSSSTDSANEKPALIPR 17 1 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;Q9NUQ6-2;F8VT91;F2Z2S1;C9JKE4;F8VZ02;C9JGM8;C9JW67;F8W6C2 B8ZZZ7 SPATS2L SPATS2-like protein 1 DS(0.078)S(0.311)S(0.311)T(0.096)DS(0.204)ANEKPALIPR 58.635 0.019601 4471800.0 9739.1 11821.0 11483.0 9658.4 10615.0 11049.0 10691.0 10531.0 9151.0 8387.0 True False 9600.2186480678 11793.629200780071 10538.912065661838 10368.7109554779 9990.646569892959 10576.460026476994 11244.527668535247 11020.308705305615 8120.318015697975 9836.68177502497 0.9759610880614698 1.1989438583571677 1.0713889405693502 1.0540862449981594 1.0156521069187072 1.0752060774528966 1.1431220329892906 1.1203278663833405 0.8255139488516555 1.0 13.26395601546438 -8.250770393783997 24.98988300419288 0.9127569696278947 1.0840821336428152 0.47392934362117334 0.07122349686507315 508.32322262411 1190648.835383395 0.047533740223725064 0.01756082285797105 5.613446737041101e-09 8.250770393783997 0.1713251640149206 DSS(ph)TSPGDYVLSVSENSR ddPTM_PC-9_AZD4547_30min_R2 3 DSSTSPGDYVLSVSENSR 18 0 I3L297;P46108-2;P46108 I3L297 CRK Adapter molecule crk 1 DS(0.024)S(0.97)T(0.006)SPGDYVLSVSENSR;DS(0.003)S(0.963)T(0.017)S(0.017)PGDYVLSVSENSR;DS(0.007)S(0.984)T(0.01)SPGDYVLSVSENSR 330.65 1.7047999999999995e-177 33066900.0 79736.0 90181.0 93289.0 84008.0 107100.0 101561.0 96562.0 118812.0 104753.0 95298.0 True False 105090.38938816923 119330.24466442774 92051.9269060502 64641.25351066177 92231.01368056796 95210.37461493474 105155.8309346195 100452.33542815024 110290.02972251209 91961.6460264536 1.1427632489085617 1.2976088382552582 1.0009817231802336 0.7029153598671682 1.0029291304120076 1.035326994772871 1.1434748667327082 1.092328593153435 1.199304650231969 1.0 16.48874466871286 -9.647658828868376 14.930830110825834 0.9999988829734318 1.0626019330269505 0.017071353798764677 0.15008066747301574 0.0 0.0 0.16002720626448527 0.038812298494175126 2.2508221023314896e-10 9.647658828868376 0.06260305005351874 DSS(ph)TSPGDYVLSVSENSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 DSSTSPGDYVLSVSENSR 18 0 I3L297;P46108-2;P46108 I3L297 CRK Adapter molecule crk 1 DS(0.398)S(0.586)T(0.016)SPGDYVLSVSENSR;DSS(0.984)T(0.013)S(0.003)PGDYVLSVSENSR;DS(0.055)S(0.896)T(0.049)SPGDYVLSVSENSR;DS(0.17)S(0.657)T(0.17)S(0.004)PGDYVLSVSENSR;DSS(0.962)T(0.019)S(0.019)PGDYVLSVSENSR 294.94 6.4219999999999975e-121 38003600.0 87819.5 138957.3 120101.4 107234.54000000001 122949.6 74697.3 111039.7 82824.4 74595.5 71949.1 True False 102685.60683581136 152752.06240719708 122965.0728630962 101226.53638286958 98858.5084810885 70780.04209091865 100521.21575818949 80650.34725970574 75686.31806667893 84992.90228123758 1.2081668478154732 1.7972331607379117 1.4467687249484724 1.1909998795889527 1.1631384012981494 0.8327759164725399 1.1827012969338244 0.948906850984303 0.8905016305507065 1.0 16.37505474702084 -5.993203259006508 1.6972689089218638 0.9895550389094849 1.5276733632682276 0.6319862492089142 0.16520254351830924 0.21865914793848423 1.2706742775797366 0.05333426446559234 0.08955313003590123 1.0157731782643617e-06 5.993203259006508 0.5381183243587426 DSS(ph)TSPGDYVLSVSENSR ddPTM_PC-9_Lapatinib_30min_R1 3 DSSTSPGDYVLSVSENSR 18 0 I3L297;P46108-2;P46108 I3L297 CRK Adapter molecule crk 1 DSS(0.978)T(0.011)S(0.011)PGDYVLSVSENSR;DS(0.001)S(0.957)T(0.021)S(0.021)PGDYVLSVSENSR;DS(0.002)S(0.988)T(0.009)S(0.001)PGDYVLSVSENSR 333.65 1.1614999999999996e-198 30677100.0 45743.0 93234.0 97220.0 87557.0 117872.0 99151.0 108433.0 108033.0 99549.0 101006.0 True False 45090.69643176116 93018.12240128004 89226.94688005258 93996.2338615897 110939.00070526823 94910.54286226985 114047.1301732561 113052.60757385631 88336.74332255688 118464.75251796526 0.3806254221053906 0.7851966126985643 0.7531940512560582 0.793453173739042 0.9364726498579757 0.8011711572003377 0.9627093945598778 0.9543143016882748 0.7456795497813626 1.0 16.85409834426219 -4.5344147575967675 1.1338532411316942 0.8824274895939269 2.1970491039895253e-39 0.7323563798019582 0.08793598846890965 1.376603822382312 1.0275125629018804 0.026254049043923 1.6540458296780156 2.921361102522391e-05 4.5344147575967675 -0.8824274895939269 down DSS(ph)VEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DSSVEVR 7 0 O15371-2;O15371-3;O15371;B0QYA6;B0QYA5 O15371-2 EIF3D Eukaryotic translation initiation factor 3 subunit D 1 DS(0.022)S(0.978)VEVR;DS(0.02)S(0.98)VEVR 104.06 0.010406 35935000.0 267710.0 231580.0 263130.0 354720.0 406460.0 303720.0 328160.0 343780.0 291140.0 264610.0 True False 313028.01548648137 254569.73194109733 269404.0171260814 334846.1884177559 326817.080797524 287792.3885314974 297074.3091273432 334756.13926501956 295397.3717172327 312581.6983483921 1.001427841554536 0.8144102271060133 0.8618675327108037 1.0712277468162854 1.0455413177558006 0.920694941681245 0.9503893244454609 1.070939664842158 0.9450245272773251 1.0 18.253873785484025 -5.74587866393307 24.98785369019783 0.999959080714512 0.8847526684942015 0.36084960590752935 0.06560326493140826 250.78156986893407 402709.12958601647 0.0179158619981991 0.030891631894145545 1.7952351214446343e-06 5.74587866393307 -0.11520641222031047 DSSDS(ph)ADGRATPSENLVPSSAR ddPTM_PC-9_AZD4547_30min_R2 3 DSSDSADGRATPSENLVPSSAR 22 1 Q8N684-2;Q8N684;Q8N684-3;F5H669;F5H6M0;F5H047 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 1 DS(0.061)S(0.225)DS(0.708)ADGRAT(0.005)PSENLVPSSAR;DS(0.013)S(0.013)DS(0.733)ADGRAT(0.237)PS(0.005)ENLVPSSAR;DS(0.019)S(0.056)DS(0.666)ADGRAT(0.255)PS(0.006)ENLVPSSAR 77.554 0.0003386 226789000.0 158340.0 137835.0 179084.0 261850.0 216963.0 204617.0 162204.0 234889.0 190440.0 216213.0 True False 208688.8263234016 182387.4682396668 176709.2291485933 201484.52804217173 186841.4325039873 191822.26664353587 176639.84176921565 198592.30226225223 200506.2696090346 208643.44868011557 1.0002174889438087 0.8741586155398368 0.8469435789451379 0.9656882558104203 0.8955058674784737 0.919378335897959 0.8466110145640534 0.9518262064711488 0.9609995946551066 1.0 17.670680095708647 -7.985678937064666 24.70477140974218 0.9724708531902906 0.9052007519208964 0.2936037058033645 0.04654205256282996 242.91364670854438 419041.4631965555 0.024951797019339066 0.011977947956968797 1.033525182455189e-08 7.985678937064666 -0.06727010126939414 DSSDS(ph)ADGRATPSENLVPSSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSSDSADGRATPSENLVPSSAR 22 1 Q8N684-2;Q8N684;Q8N684-3;F5H669;F5H6M0;F5H047 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 1 DS(0.077)S(0.077)DS(0.547)ADGRAT(0.267)PS(0.031)ENLVPSS(0.001)AR 53.254 0.009373000000000001 90913000.0 90601.0 80290.0 99836.0 118690.0 117830.0 96103.0 100380.0 109480.0 103420.0 87425.0 True False 105937.95984868247 88260.66058187583 102216.46887013831 112040.18409817168 94742.05734973222 91063.18950033745 90871.27971173427 106606.26600364831 104932.32184858219 103274.46044408092 1.0257904945051126 0.8546223354966402 0.989755535207899 1.0848779419073997 0.9173812861605928 0.8817590438988021 0.879900793681101 1.0322616602908463 1.016052966022504 1.0 16.65612399731124 -7.795466908357946 24.99962746424267 1.0181180628751452 0.9473329633826438 0.17651118407297117 0.0676356909415269 355.01768080224184 260822.77935412424 0.03908248995042513 0.018776170742776176 1.601522673832206e-08 7.795466908357946 -0.07078509949250134 DSSDS(ph)ADGRATPSENLVPSSAR ddPTM_PC-9_Lapatinib_30min_R1 2 DSSDSADGRATPSENLVPSSAR 22 1 Q8N684-2;Q8N684;Q8N684-3;F5H669;F5H6M0;F5H047 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 1 DS(0.006)S(0.068)DS(0.745)ADGRAT(0.18)PS(0.001)ENLVPSSAR;DS(0.059)S(0.187)DS(0.611)ADGRAT(0.142)PS(0.001)ENLVPSSAR 74.324 0.00045377 125419000.0 146695.0 113305.0 139581.0 116398.0 127840.0 112386.0 108568.0 93599.0 139502.0 89775.0 True False 144603.10239943143 113042.64923393849 128105.1889782412 124958.29721234538 120320.70254311043 107579.51276456182 114189.11981269628 97947.95123994857 123789.81573881554 105292.48913233177 1.3733467941639599 1.0736060108890226 1.216660276852591 1.1867731330322868 1.1427282566365315 1.0217206721113385 1.0844944473597087 0.930246326657236 1.1756756513110473 1.0 16.684043002177376 -6.5534516268894265 2.378417393058381 1.0395350146205942 1.2040231683591973 0.4410094079286355 0.09005412287814193 0.28632645122817635 3.2732932584828314 0.030553355928318524 0.03215790149179214 2.7960721457094045e-07 6.5534516268894265 0.16448815373860315 DSSDSADGRAT(ph)PSENLVPSSAR ddPTM_PC-9_AZD4547_30min_R2 1 DSSDSADGRATPSENLVPSSAR 22 1 Q8N684-2;Q8N684;Q8N684-3;F5H669;F5H6M0;F5H047 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 1 DS(0.015)S(0.015)DS(0.054)ADGRAT(0.915)PSENLVPSSAR 67.47800000000001 0.0017973 15041000.0 17622.0 13300.0 14919.0 26887.0 24565.0 22480.0 14706.0 25829.0 18374.0 22197.0 True False 23225.429439629796 17598.964904324515 14721.164312098575 20688.61755000908 21154.573772765176 21074.322046294663 16014.805510703074 21837.721541373656 19345.212128735562 21419.889786240983 1.084292667768468 0.82161790186377 0.6872661091633946 0.9658601307695974 0.9876135677576533 0.9838669692797255 0.7476605001483316 1.019506718255902 0.9031424681354764 1.0 14.386663436423209 DSSDSADGRAT(ph)PSENLVPSSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DSSDSADGRATPSENLVPSSAR 22 1 Q8N684-2;Q8N684;Q8N684-3;F5H669;F5H6M0;F5H047 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 1 DSSDS(0.028)ADGRAT(0.971)PS(0.001)ENLVPS(0.001)SAR;DS(0.008)S(0.008)DS(0.004)ADGRAT(0.928)PS(0.049)ENLVPS(0.001)S(0.001)AR 128.66 9.1612e-05 79766500.0 129851.3 97428.6 118796.3 148849.8 153794.1 157578.4 132618.5 177091.7 121965.8 101693.0 True False 151832.5604099207 107100.66752481401 121628.85432947657 140510.22828356293 123659.25012518463 149314.71130308096 120055.91560520674 172443.23051916578 123749.31908837553 120129.13589865471 1.2639112008431672 0.891546140939264 1.0124842189166088 1.169659860053455 1.0293859953301259 1.2429516801739775 0.9993904868048852 1.4354821520121908 1.0301357631738477 1.0 16.87422657650982 -6.369338115964104 1.394727684413942 1.1574297995969836 1.0526821410408063 0.01431893135941087 0.1554770576662979 1.1911645175434464 4.696233911708469 0.059189442163834795 0.07521067247546459 4.2723014055409563e-07 6.369338115964104 -0.10474765855617729 DSSDSADGRAT(ph)PSENLVPSSAR ddPTM_PC-9_Lapatinib_30min_R1 2 DSSDSADGRATPSENLVPSSAR 22 1 Q8N684-2;Q8N684;Q8N684-3;F5H669;F5H6M0;F5H047 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 1 DS(0.005)S(0.013)DS(0.041)ADGRAT(0.94)PS(0.001)ENLVPSSAR;DS(0.027)S(0.023)DS(0.25)ADGRAT(0.676)PS(0.025)ENLVPSSAR 61.806999999999995 0.0042306 123894000.0 105157.0 87204.0 96082.0 72511.3 96503.0 87187.0 73617.3 78469.4 103726.0 82508.0 True False 103657.44189656778 87002.08449579772 88182.50884724552 77844.02289260589 90826.88327219781 83458.2152528237 77428.84358178469 82115.37479062848 92043.28559679684 96769.39786500066 1.071179982345001 0.8990660933652915 0.9112644161562896 0.804428100309182 0.9385909727257679 0.8624442963802783 0.8001377014849544 0.8485675906052919 0.9511610863302359 1.0 16.56226326456435 -4.662517449150532 2.500616657096069 0.8790070467692453 1.1585476722279462 0.43073772672529 0.06126995702440996 0.7802526075747475 4.469984026198168 0.01534827865932848 0.5323701673460737 2.1751166400927534e-05 4.662517449150532 0.27954062545870084 DSSFTEVPRS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 DSSFTEVPRSPK 12 1 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 DSS(0.006)FT(0.206)EVPRS(0.788)PK 120.59 0.002345 33660000.0 28364.0 28465.0 23239.0 22181.0 25822.0 24642.0 24312.0 22753.0 29192.0 22964.0 True False 27959.524158679455 28399.091041384385 21328.37912513417 23812.2647336469 24303.200728005286 23588.119103307643 25570.7564004704 23810.18744391024 25904.08955461213 26933.296802393405 1.0381025525324792 1.0544231272445164 0.7918963386331095 0.8841199392838847 0.9023477855798776 0.8757976892458076 0.9494105600246486 0.8840428120850904 0.9617868077817411 1.0 14.717103215009264 -5.231037116295412 24.866372137326522 0.9015687318621466 1.0462629161139299 0.5181524454959788 0.053890039844969775 471.56218025141004 385694.7871345481 0.013193538061495787 0.03489733227323555 5.87439145820938e-06 5.231037116295412 0.14469418425178326 DSSGS(ph)FSPCQPFLEK ddPTM_PC-9_Lapatinib_30min_R1 1 DSSGSFSPCQPFLEK 15 0 H3BMJ2;Q6ZRI6-2;Q6ZRI6 H3BMJ2 C15orf39 Uncharacterized protein C15orf39 1 DSSGS(0.934)FS(0.066)PCQPFLEK 179.97 2.5560999999999998e-05 3434300.0 12715.0 13572.0 17056.0 11456.0 13433.0 14056.0 12785.0 12428.0 15720.0 11092.0 True False 12533.681768354574 13540.574867861185 15653.721518063961 12298.512456095703 12642.897350294128 13454.857646136354 13446.944742514555 13005.450250644593 13949.448061061323 13009.237420839032 0.9634447710422532 1.0408430894013068 1.203277410633526 0.9453676690068824 0.9718400042451315 1.0342541388770028 1.0336458861896376 0.9997088860728783 1.0722725406422517 1.0 13.667248775777471 DSSGSFS(ph)PCQPFLEK ddPTM_PC-9_AZD4547_30min_R2 1 DSSGSFSPCQPFLEK 15 0 H3BMJ2;Q6ZRI6-2;Q6ZRI6 H3BMJ2 C15orf39 Uncharacterized protein C15orf39 1 DSSGS(0.073)FS(0.927)PCQPFLEK 160.03 0.00027638 3055700.0 14083.0 14268.0 13483.0 19219.0 17911.0 18117.0 13761.0 17518.0 15400.0 21027.0 True False 18561.101055402698 18879.851974052806 13304.206610364305 14788.356480590031 15424.36681636462 16984.141126010687 14985.702341410655 14810.995623593013 16214.012560276879 20290.85113012068 0.9147522169658885 0.9304613124890891 0.6556751377774844 0.7288189335063184 0.7601636184431896 0.8370344357215572 0.7385447877622631 0.7299346650671978 0.7990799625062571 1.0 14.308541761916096 -5.231240987532474 24.424724507160583 0.7693661060062529 0.9226068655442046 0.28923370575357266 0.08714154719605123 567.769698394624 459214.53227241134 0.020820404204393288 0.0550686320563934 5.871634484663382e-06 5.231240987532474 0.1532407595379517 DSSGSFS(ph)PCQPFLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSSGSFSPCQPFLEK 15 0 H3BMJ2;Q6ZRI6-2;Q6ZRI6 H3BMJ2 C15orf39 Uncharacterized protein C15orf39 1 DSSGSFS(1)PCQPFLEK 120.59 0.0013085999999999998 0.0 12009.0 11673.0 13523.0 18913.0 18002.0 15294.0 15312.0 14943.0 12671.0 9976.8 True False 14041.886511438366 12831.818295830539 13845.439606263099 17853.365926773313 14474.637328438288 14491.95571645173 13861.536510720012 14550.762083417238 12856.289403823115 11785.514863694654 1.1914529550757667 1.0887787631034287 1.1747844507764404 1.5148566807013844 1.228171827522571 1.2296412913698223 1.176150271840949 1.2346310069355513 1.0908551346727318 1.0 13.524727165296964 -8.446083361067421 2.0015454563143797 0.9986795421285659 1.2334071468543726 0.34708451855852884 0.1044417393422648 0.3858733621787377 3.3423950454584834 0.10698202060122233 0.030158418136210025 3.5802770853769815e-09 8.446083361067421 0.23472760472580667 DSSGSVS(ph)PNTLSQEEGDQICLYHIR ddPTM_PC-9_AZD4547_30min_R2 1 DSSGSVSPNTLSQEEGDQICLYHIR 25 0 H7C4T3;H7C4L8;G5E9U9;Q9H0J9 H7C4T3 PARP12 Poly [ADP-ribose] polymerase 12 1 DS(0.014)S(0.048)GS(0.048)VS(0.667)PNT(0.222)LSQEEGDQICLYHIR 96.34100000000001 1.3772e-06 6052900.0 22080.0 22789.0 37134.0 42274.0 41057.0 40513.0 32067.0 44555.0 37059.0 41033.0 True False 29100.98070746942 30155.09858681588 36641.578897075415 32528.382426789285 35356.94424540687 37979.71570558432 34920.90087798963 37670.04852204513 39017.863082552 39596.44715947319 0.7349391876060578 0.7615607144087287 0.925375419403232 0.821497501929465 0.8929322396781741 0.9591697849209162 0.8819200555379888 0.9513492049003902 0.9853879800227793 1.0 15.273083368052426 -2.6687359997275646 0.25458209311743507 0.9933905297630683 8.448605048465129e-12 0.7815200161779055 0.04082505426811678 13.301763607542545 0.3034115443815593 0.052996502411961605 5.0517250654174815 0.0021441936240868672 2.6687359997275646 -0.9933905297546197 DSSGSVS(ph)PNTLSQEEGDQICLYHIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DSSGSVSPNTLSQEEGDQICLYHIR 25 0 H7C4T3;H7C4L8;G5E9U9;Q9H0J9 H7C4T3 PARP12 Poly [ADP-ribose] polymerase 12 1 DS(0.059)S(0.059)GS(0.049)VS(0.774)PNT(0.059)LSQEEGDQICLYHIR;DS(0.024)S(0.024)GS(0.068)VS(0.625)PNT(0.239)LS(0.021)QEEGDQICLYHIR;DS(0.062)S(0.062)GS(0.062)VS(0.779)PNT(0.035)LS(0.001)QEEGDQICLYHIR 91.249 2.9495999999999997e-06 11113300.0 22055.0 21075.9 24328.9 28579.2 31729.9 26092.7 29419.2 27448.7 30292.3 27818.1 True False 25788.475893893996 23168.176066229338 24908.99324386706 26978.000079016547 25512.653869993002 24724.352878426842 26632.400399436658 26728.20070930167 30735.26758009872 32861.301322041574 0.7847673359361605 0.7050291721310923 0.7580038599128592 0.8209656645861791 0.7763738149006443 0.7523850816535708 0.8104487445107078 0.8133640371501005 0.9353028134489358 1.0 15.004101992329291 -8.299080712770754 1.3301005725779964 1.0028630600063568 0.7670086397129473 0.8766201603330823 0.02947633697285495 0.13798932829677205 0.48866539890492505 0.02913345463372054 0.009110781697314744 5.022492388201699e-09 8.299080712770754 -0.23585442029340953 DSSGSVS(ph)PNTLSQEEGDQICLYHIR ddPTM_PC-9_Lapatinib_30min_R1 1 DSSGSVSPNTLSQEEGDQICLYHIR 25 0 H7C4T3;H7C4L8;G5E9U9;Q9H0J9 H7C4T3 PARP12 Poly [ADP-ribose] polymerase 12 1 DS(0.029)S(0.029)GS(0.026)VS(0.836)PNT(0.079)LSQEEGDQICLYHIR 92.822 2.1876e-06 5687200.0 11647.0 17214.0 21127.0 11688.0 18184.0 22887.0 19446.0 17914.0 22347.0 16244.0 True False 11480.911644201784 17174.142040625 19390.019612578402 12547.574510025011 17114.45287111952 21908.176362202827 20452.818729991253 18746.34983827224 19830.0455356576 19051.753756230544 0.6026170499105444 0.9014467780956121 1.0177551033188865 0.6586046970044186 0.8983137767840683 1.1499296412561568 1.0735399476440595 0.9839697740236419 1.0408514507055566 1.0 14.217636186662318 -6.563248314280411 6.8805263670088825 1.048523159379288 0.813609474804443 0.5149757408470812 0.1164020276231803 0.17492712423198353 22.304291274076995 0.03893058213491692 0.03916704338970422 2.73370524305355e-07 6.563248314280411 -0.23491368457484507 DSSGSVSPNT(ph)LSQEEGDQICLYHIR ddPTM_PC-9_AZD4547_30min_R2 2 DSSGSVSPNTLSQEEGDQICLYHIR 25 0 H7C4T3;H7C4L8;G5E9U9;Q9H0J9 H7C4T3 PARP12 Poly [ADP-ribose] polymerase 12 1 DS(0.031)S(0.031)GS(0.012)VS(0.084)PNT(0.79)LS(0.053)QEEGDQICLYHIR;DS(0.01)S(0.01)GS(0.009)VS(0.129)PNT(0.809)LS(0.033)QEEGDQICLYHIR 95.624 5.4277e-06 9378400.0 23217.3 21068.0 44137.0 59137.5 49267.9 52425.1 35870.3 63461.5 34406.0 40972.2 True False 30599.918450159872 27877.818992805194 43551.714541396505 45504.26304026713 42427.902510857624 49146.950209484115 39062.68721002128 53654.983375193966 36224.630918758885 39537.7757489671 0.7739413224568982 0.7050932548610422 1.1015216136060528 1.1509059925166858 1.0730978591269396 1.243037810764255 0.9879839335939824 1.35705619142209 0.916203054738233 1.0 15.270944092139228 -5.266792010030114 21.922201999794524 1.1179108325517435 0.7395171910133492 0.5839720979292289 0.12249603222100694 43.182095822421566 176862.78791789888 0.02898803142015489 0.06367911622237894 5.410133601114872e-06 5.266792010030114 -0.3783936415383943 DSSGSVSPNT(ph)LSQEEGDQICLYHIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSSGSVSPNTLSQEEGDQICLYHIR 25 0 H7C4T3;H7C4L8;G5E9U9;Q9H0J9 H7C4T3 PARP12 Poly [ADP-ribose] polymerase 12 1 DS(0.017)S(0.076)GS(0.017)VS(0.28)PNT(0.609)LS(0.001)QEEGDQICLYHIR 121.0 7.7742e-09 4360900.0 19918.0 23273.0 27875.0 27596.0 31986.0 26611.0 25780.0 29653.0 28354.0 22193.0 True False 23289.72400156794 25583.389634101277 28539.64571652619 26049.88558743914 25718.57291342222 25215.472314011855 23337.931768963037 28874.64016995055 28768.623609502065 26216.41522030866 0.8883641720598954 0.975853846497022 1.0886173977904434 0.9936478869643278 0.981010282958107 0.9618199933940084 0.890203011084605 1.101395439738942 1.0973515397794098 1.0 14.678182807387753 -7.78422887642833 24.999775893028534 1.0745301582849731 0.9745960999223581 0.3594494668910406 0.059097587298499635 276.38565789981567 303187.0173625865 0.03364847656380733 0.016181533000000636 1.6435053553741296e-08 7.78422887642833 -0.09993405836261504 DSSGSVSPNT(ph)LSQEEGDQICLYHIR ddPTM_PC-9_Lapatinib_30min_R1 1 DSSGSVSPNTLSQEEGDQICLYHIR 25 0 H7C4T3;H7C4L8;G5E9U9;Q9H0J9 H7C4T3 PARP12 Poly [ADP-ribose] polymerase 12 1 DS(0.06)S(0.06)GS(0.003)VS(0.389)PNT(0.488)LSQEEGDQICLYHIR 112.36 2.4218e-07 5830000.0 19093.0 28424.0 30900.0 24821.0 26211.0 34930.0 29788.0 27285.0 38321.0 29038.0 True False 18820.730318772625 28358.185974365362 28359.52127744937 26646.41914042872 24669.320512808696 33436.12532580699 31330.27688619662 28552.760708789658 34004.885441980376 34057.179609297156 0.5526215187130415 0.8326639580754935 0.8327031657579654 0.7824024022574847 0.7243500723141002 0.9817643653815472 0.9199316339643073 0.8383771362263696 0.9984645185562429 1.0 15.055671345036895 -3.1080588145231807 0.22143107227887035 0.9999817132521905 4.3265808828639714e-14 0.6124856401434255 0.08262827500007648 19.595212581716606 0.4594291708325881 0.1380366438805891 6.076513175137529 0.0007797245088347804 3.1080588145231807 -0.9999817132521472 DSSIIDPGTEQDLPS(ph)PENSSVK ddPTM_PC-9_AZD4547_30min_R2 1 DSSIIDPGTEQDLPSPENSSVK 22 0 H7C183;Q70CQ2-3;Q70CQ2-2;Q70CQ2;H7C150 H7C183 USP34 Ubiquitin carboxyl-terminal hydrolase 34 1 DSSIIDPGTEQDLPS(0.949)PENS(0.038)S(0.013)VK 79.383 0.0029358 0.0 14975.0 18659.0 20619.0 27091.0 22887.0 19873.0 16402.0 25307.0 19070.0 20663.0 True False 19736.73850065012 24690.15685336775 20345.578587784727 20845.58850177764 19709.535108376822 18630.338168416998 17861.746225115734 21396.384647006977 20078.001267823394 19939.594659327704 0.9898264652745743 1.2382476813197274 1.0203606911471044 1.0454369237654546 0.9884621751403928 0.9343388612818045 0.8957928448540474 1.0730601605784293 1.006941294989211 1.0 14.283348461857193 -5.7505976062500315 1.8962597868132949 0.9822238290112959 1.1116575490285778 0.27874822678342204 0.07419770067904287 0.39777656486777746 2.9145644249329887 0.022666333220455474 0.04632198789503174 1.77583411058589e-06 5.7505976062500315 0.12943372001728193 DSSIIDPGTEQDLPS(ph)PENSSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DSSIIDPGTEQDLPSPENSSVK 22 0 H7C183;Q70CQ2-3;Q70CQ2-2;Q70CQ2;H7C150 H7C183 USP34 Ubiquitin carboxyl-terminal hydrolase 34 1 DSSIIDPGTEQDLPS(0.996)PENS(0.002)S(0.002)VK;DSSIIDPGTEQDLPS(0.988)PENS(0.005)S(0.007)VK 97.488 7.673100000000001e-05 2572900.0 22419.3 24826.0 30112.0 30811.0 33152.0 26175.0 28909.0 24236.6 25509.0 23431.0 True False 26214.444688641022 27290.561210681815 30829.98428039592 29084.759560609764 26656.103583623277 24802.336921545968 26170.530236964787 23600.414930800394 25882.020866713272 27678.854820306067 0.947092820813139 0.9859714712857489 1.113846092280454 1.0507934576567914 0.9630493659032284 0.8960752560958629 0.9455062504163024 0.852651422322805 0.9350827927940653 1.0 14.756496633967632 -6.478218734925617 4.108698062696575 0.9183377594266855 1.027301539096144 0.4243733477168401 0.05364408809658215 0.20490638066442485 7.354470487868701 0.018080629532274926 0.019853902516502715 3.3249204957318333e-07 6.478218734925617 0.10896377966945847 DSSLCVSGETLAAGT(ph)SSPK ddPTM_PC-9_AZD4547_30min_R2 1 DSSLCVSGETLAAGTSSPK 19 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 DSSLCVSGETLAAGT(0.557)S(0.375)S(0.067)PK 92.427 0.0021488 5889400.0 17456.0 23762.0 16351.0 13904.0 17137.0 23248.0 22096.0 20740.0 18799.0 16586.0 True False 23006.644892644286 31442.60180876383 16134.175056446391 10698.647614658616 14757.823356152117 21794.298884886943 24062.50119437611 17535.109557787357 19792.676761080857 16005.329188385493 1.4374365326605967 1.9645082858764709 1.008050185444133 0.6684428348041882 0.9220568463447383 1.3616901363517286 1.503405578926638 1.0955794380356745 1.2366304077921564 1.0 13.966264729258143 -5.271424143879484 24.98565278345264 1.1049550251796623 1.7009724169797382 0.48057370562568513 0.25008103471485177 554.763868208377 1388230.2361148074 0.07179534808522772 0.15234962386066864 5.35273639269156e-06 5.271424143879484 0.596017391800076 DSSLCVSGETLAAGTS(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 1 DSSLCVSGETLAAGTSSPK 19 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 DSSLCVSGETLAAGT(0.001)S(0.929)S(0.07)PK 218.64 1.3292999999999998e-86 0.0 32094.0 26895.0 21166.0 21133.0 21481.0 28897.0 32071.0 25493.0 30135.0 22348.0 True False 42299.224403329885 35588.28278960961 20885.325010381275 16261.113351595255 18498.73393905023 27090.066021876195 34925.25687024061 21553.64262086177 31727.874578178187 21565.60332220181 1.9614208687490229 1.6502335806655335 0.968455400868837 0.754030068560819 0.8577888437744641 1.2561700972208343 1.619488977351495 0.9994453806294524 1.4712259195417134 1.0 14.396444457215795 -5.081334327959809 3.744435564832923 1.1183972457134523 1.9143597459713646 0.5505218829616854 0.25582221088694934 0.17963465457350386 4.6238988670579575 0.07226841809026484 0.247166935221189 8.292121788081892e-06 5.081334327959809 0.7959625002579123 DSSLCVSGETLAAGTS(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSSLCVSGETLAAGTSSPK 19 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 DSSLCVSGETLAAGT(0.162)S(0.815)S(0.023)PK 170.0 7.538299999999999e-28 0.0 11572.0 17129.0 12420.0 12833.0 12752.0 10866.0 18043.0 14037.0 11846.0 9366.2 True False 13530.911042581796 18829.45391838271 12716.139903112298 12114.008615147352 10253.337140997945 10296.167831500234 16333.83641999225 13668.543623430882 12019.225339569772 11064.217917201597 1.2229432883408071 1.7018332483408938 1.1493030956433397 1.0948815999288697 0.9267114239549664 0.930582523640711 1.4762757333799392 1.235382719837823 1.0863149505473333 1.0 13.433613856277935 -5.390591005849273 7.852126617781885 1.117961565255781 1.4609418497825923 0.3635050782238388 0.18550848566198766 0.2881377663885951 16.881894925037045 0.05023281615561577 0.1050306557795416 4.068262749546787e-06 5.390591005849273 0.3429802845268113 DSSLCVSGETLAAGTS(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 2 DSSLCVSGETLAAGTSSPK 19 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 DSSLCVSGETLAAGT(0.001)S(0.702)S(0.297)PK;DSSLCVSGETLAAGTS(0.978)S(0.022)PK 192.23 8.1098e-12 12757000.0 73615.0 120858.0 77255.0 100321.0 123039.0 109017.0 125688.0 116243.0 85714.0 97495.0 True False 72565.23660066219 120578.16072649317 70903.39211292405 107698.9410010453 115802.08792398119 104354.5970410393 132195.50964389296 121644.07414593508 76059.98671156565 114346.88084607826 0.6346061743331842 1.054494533076095 0.6200728134278253 0.9418616424353392 1.0127262507480355 0.9126142861868746 1.1560919604080906 1.0638162864248089 0.6651688804170321 1.0 16.803057486891518 -5.975133374857453 24.396450853064433 0.9781074640678131 0.7953289781429085 0.225948336023588 0.16328976329688646 268.0832426880216 263011.70367370587 0.044483376804997185 0.06597617828730466 1.0589284709338922e-06 5.975133374857453 -0.18277848592490464 DSSPSSSPS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 DSSPSSSPSPK 11 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 DSSPS(0.001)S(0.001)S(0.005)PS(0.993)PK 113.52 0.0015527000000000002 8200600.0 58387.0 48806.0 28428.0 30081.0 27319.0 30462.0 33780.0 29846.0 27662.0 27606.0 True False 76952.85147495543 64581.58504665131 28051.02614547476 23146.290196817165 23526.22841026549 28557.20632447633 36786.35455946891 25233.986492850596 29124.15684690775 26639.52234261243 2.8886723449940424 2.424277140410546 1.052985327015586 0.8688703160338761 0.8831325167055667 1.0719864251768654 1.3808939246866927 0.9472386992647558 1.0932687332880933 1.0 14.701280594086166 -5.185780671744444 3.32303384429253 1.0298048563503206 2.8062669055185876 0.9541264909269528 0.14346750474468012 0.04912560725879133 1.0408050626837433 0.04144459320979138 0.13255616795002473 6.5195756382922325e-06 5.185780671744444 1.776462049168267 up DSSPSSSPS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DSSPSSSPSPK 11 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 DSSPS(0.001)S(0.003)S(0.008)PS(0.988)PK;DSSPS(0.006)S(0.03)S(0.044)PS(0.921)PK;DSSPS(0.001)S(0.001)S(0.002)PS(0.995)PK;DSSPS(0.001)S(0.004)S(0.004)PS(0.992)PK 124.38 0.00051456 21650200.0 151903.0 172130.0 72699.0 95446.0 82938.0 61578.0 89775.0 64378.0 56993.9 62840.0 True False 177617.1776789922 189217.92883246046 74432.41987249286 90098.47006010698 66686.89427541471 58348.74127812638 81270.86208528554 62688.14571412934 57827.32796563444 74232.39455883364 2.3927178792302044 2.54899400668658 1.002694582531629 1.2137351973564388 0.8983529990072102 0.7860280087271264 1.094816657448299 0.8444850268765777 0.7790039417333198 1.0 16.179761287020355 -5.264556952202046 23.453727469671065 0.9533844333654059 2.470856180240383 0.9539948978032418 0.13338121892878527 19.561816844256725 147168.80719525952 0.036357712639352266 0.08137591167347721 5.438048139539247e-06 5.264556952202046 1.517471746874977 DSSPSSSPS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 DSSPSSSPSPK 11 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 DSSPS(0.005)S(0.005)S(0.025)PS(0.965)PK;DSSPS(0.003)S(0.007)S(0.03)PS(0.961)PK 123.26 0.00058861 14031700.0 38279.0 64340.0 46751.0 51179.0 60916.0 45512.0 50829.0 55482.0 50818.0 58086.0 True False 37733.13444049112 64191.02468303782 42907.3132440788 54942.87438813911 57333.04064546394 43565.55785365379 53460.67691179292 58059.89626699901 45094.34170273629 68126.0877052702 0.5538720292251877 0.942238529250991 0.6298220650759535 0.8064880318070689 0.8415724809195037 0.6394842170025797 0.7847313520053675 0.8522417508866802 0.6619247225501225 1.0 16.05591973866725 -11.222769019001877 2.7651892949820085 1.0363743172631494 0.7539324692006604 0.30123620079475477 0.11554510790306466 57218290.756317854 49886656.39359761 14516525.748974025 0.02626092550210843 5.987299469543377e-12 11.222769019001877 -0.28244184806248906 DSSS(ph)LSSCTSGILEER ddPTM_PC-9_AZD4547_30min_R2 1 DSSSLSSCTSGILEER 16 0 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 DSS(0.061)S(0.938)LS(0.001)S(0.001)CTSGILEER 102.39 0.0015080999999999998 3136400.0 11166.0 9423.2 11806.0 18312.0 13743.0 18252.0 13561.0 17304.0 12506.0 11014.0 True False 14716.55573277189 12469.06511928051 11649.44472609664 14090.451317579727 11835.021671447657 17110.699554669503 14767.902728861995 14630.06440636222 13167.041628494986 10628.403212400694 1.3846440936302966 1.1731832966905342 1.0960672542517627 1.3257354878237673 1.1135277270662014 1.6099031258717762 1.3894752046696477 1.3765063400391686 1.2388541689058554 1.0 13.375637245412644 DSSS(ph)LSSCTSGILEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSSSLSSCTSGILEER 16 0 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 DS(0.004)S(0.24)S(0.735)LS(0.019)S(0.002)CT(0.001)SGILEER 97.823 0.01295 0.0 7198.1 10085.0 9995.6 11287.0 11628.0 10030.0 9156.0 10697.0 9364.1 6907.8 True False 8416.596161044592 11086.172150556928 10233.9330125241 10654.625982947722 9349.576872296426 9504.009143194125 8288.677396300449 10416.21508440836 9501.032247363279 8160.129457885291 1.0314292444112478 1.358577974500655 1.2541385605880127 1.3056932537573838 1.1457633019855769 1.1646885251324313 1.0157531739022767 1.2764766953964155 1.164323715254572 1.0 12.994376324943122 -6.354420579751191 7.234747287471043 1.137221994006657 1.2470953825951114 0.19305990082130464 0.10813375868172109 0.45192227411915253 30.638964651844425 0.032721573154148004 0.037121763322088545 4.4215996810776496e-07 6.354420579751191 0.10987338858845441 DSSS(ph)LSSCTSGILEER ddPTM_PC-9_Lapatinib_30min_R1 1 DSSSLSSCTSGILEER 16 0 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 DS(0.001)S(0.134)S(0.833)LS(0.008)S(0.019)CT(0.003)S(0.001)GILEER 102.39 0.0015080999999999998 2792900.0 21867.0 17804.0 24159.0 22552.0 25787.0 20778.0 21660.0 25556.0 20826.0 18654.0 True False 21555.17257008333 17762.775931874497 22172.740276436856 24210.5493112666 24270.259359192645 19889.37337588369 22781.448816806052 26743.425056764838 18480.356572497654 21878.31904510742 0.9852298307581198 0.8118894278510274 1.0134572144561205 1.1066000665476505 1.1093292546449143 0.9090905628936556 1.0412796691481012 1.2223711063737042 0.8446881378041865 1.0 14.417214276800214 -5.433777795883264 7.046452817829138 1.0423463634291477 0.8999026548181134 0.1948029010905804 0.10709729543448034 0.364625096587399 24.792391792799165 0.02715407858886211 0.05683373322796387 3.6831737277397073e-06 5.433777795883264 -0.14244370861103428 DSSS(ph)TDSANEKPALIPR ddPTM_PC-9_AZD4547_30min_R2 1 DSSSTDSANEKPALIPR 17 1 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;Q9NUQ6-2;F8VT91;F2Z2S1;C9JKE4;F8VZ02;C9JGM8;C9JW67;F8W6C2 B8ZZZ7 SPATS2L SPATS2-like protein 1 DS(0.149)S(0.149)S(0.488)T(0.124)DS(0.09)ANEKPALIPR 49.066 0.042542 18794000.0 29817.0 34565.0 52099.0 60520.0 55764.0 45140.0 53629.0 53732.0 59537.0 54944.0 True False 39298.18576787207 45737.46029458476 51408.13321911811 46568.049024679174 48022.131156705764 42317.38866413437 58401.877106860804 45428.95403852607 62684.00427280548 53020.42728365205 0.7411895335666033 0.8626384704501832 0.9695910774934275 0.8783039181398231 0.905728859931549 0.7981336785111541 1.1014976698399417 0.8568198403133828 1.1822613940369553 1.0 15.6942606762639 -7.259428302439399 24.99999999891174 1.0232130465377631 0.8674099514724757 0.44219240771367263 0.09614155176989292 190.16354680766457 2363969.554042618 0.03663823549808514 0.026939613290724845 5.5026475607484375e-08 7.259428302439399 -0.15580309506528744 DSSSLS(ph)SCTSGILEER ddPTM_PC-9_Lapatinib_30min_R1 1 DSSSLSSCTSGILEER 16 0 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 DS(0.003)S(0.012)S(0.279)LS(0.629)S(0.058)CT(0.018)S(0.001)GILEER 137.39 1.2915e-05 3450600.0 8630.7 10406.0 12869.0 8690.6 10358.0 12278.0 9952.9 10396.0 11241.0 9239.8 True False 8507.624635323464 10381.905546342736 11810.960495776566 9329.735714991732 9748.762804611524 11752.898561415925 10468.212462086287 10879.036112463886 9974.920207022291 10836.887118740404 0.785061664120418 0.9580154736860864 1.0898849795483871 0.8609239547081439 0.8995906940612892 1.0845271739604492 0.9659796533253021 1.0038894004580516 0.920459916000463 1.0 13.403662783538065 -6.695023560534318 24.999999999704706 0.9934101737571082 0.9271807593965866 0.17395084464619925 0.08203801508486427 122.39630177389736 46070.42100843721 0.027766824213487605 0.027766822690780978 2.018256870003695e-07 6.695023560534318 -0.06622941436052154 DSSSS(ph)LTDPQVSYVK ddPTM_PC-9_AZD4547_30min_R2 2 DSSSSLTDPQVSYVK 15 0 H7C3M7;O94887-3;O94887-2;O94887 H7C3M7;O94887-3 FARP2 FERM, RhoGEF and pleckstrin domain-containing protein 2 1 DS(0.002)S(0.011)S(0.185)S(0.798)LT(0.004)DPQVSYVK;DSS(0.008)S(0.046)S(0.946)LTDPQVSYVK 214.89 1.1489000000000001e-17 11639200.0 34007.0 45147.0 72588.0 65431.0 88135.0 71508.0 70761.0 88163.0 63452.0 70254.0 True False 44820.51861045799 59739.884852296134 71625.43569184339 50346.893848872845 75898.97657083884 67036.59345580237 77058.59191777935 74539.4341341953 66805.94318017451 67794.42884365335 0.6611239208729451 0.8811916535216705 1.0565091691682373 0.7426405784018361 1.119545925313068 0.9888215683681223 1.136650802022256 1.0994920291473682 0.9854193673383033 1.0 16.04887910114303 -3.9921724529786915 0.5843154019919246 1.0532528280082023 2.4009741440372374e-13 0.5270182268044077 0.10447767255777822 6.996424771320399 0.9137335301692671 0.05071457256904268 6.107915699796488 0.00010181869982798063 3.9921724529786915 -1.0532528280079623 DSSSS(ph)LTDPQVSYVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DSSSSLTDPQVSYVK 15 0 H7C3M7;O94887-3;O94887-2;O94887 H7C3M7;O94887-3 FARP2 FERM, RhoGEF and pleckstrin domain-containing protein 2 1 DSS(0.001)S(0.11)S(0.78)LT(0.109)DPQVSYVK;DSSS(0.001)S(0.999)LTDPQVSYVK 231.58 2.0833999999999996e-92 4067000.0 32810.0 44069.0 54946.0 56635.0 64191.0 52907.0 56101.0 47992.0 45460.0 44834.0 True False 38364.08497296134 48443.879078125225 56256.12102386542 53461.924563147404 51613.23434894908 50132.46378254949 50786.70714393307 46732.260851727224 46124.76649812951 52962.049294251265 0.7243693452988336 0.9146904193411477 1.0621968328927882 1.0094383671998584 0.9745324253257589 0.946573337901241 0.9589263976884234 0.8823725946118129 0.8709022236255517 1.0 15.692671325891217 -4.7925976326805575 3.9236037600908387 0.9617172099433122 0.7050406086031599 0.6366285367790063 0.05387138684713764 0.15868505381196998 4.468702625320546 0.01496572423508131 0.11369292893908277 1.612138565668195e-05 4.7925976326805575 -0.25667660134015235 DSSSS(ph)LTDPQVSYVK ddPTM_PC-9_Lapatinib_30min_R1 2 DSSSSLTDPQVSYVK 15 0 H7C3M7;O94887-3;O94887-2;O94887 H7C3M7;O94887-3 FARP2 FERM, RhoGEF and pleckstrin domain-containing protein 2 1 DS(0.001)S(0.006)S(0.04)S(0.941)LT(0.012)DPQVSYVK;DSSS(0.227)S(0.773)LTDPQVSYVK 282.73 6.6642e-89 12565900.0 104273.0 162013.0 129646.0 120171.0 150896.0 143238.0 115778.0 135848.0 138954.0 97268.0 True False 102786.04789867377 161637.86885254865 118987.00632803256 129008.77621870411 142020.59395295032 137112.04464408662 121772.41833389517 142159.99401750654 123303.5372695111 114080.64419853706 0.9009946307788458 1.4168737386444514 1.0430078403217713 1.1308559583007551 1.2449140250802646 1.2018870125370917 1.0674240068452974 1.2461359682550737 1.0808453803514928 1.0 16.799694508065215 -8.522783459720817 24.8069825181907 0.9999999994410042 1.162131986661751 0.12457612435056176 0.13142086187646113 14.175978677281226 3690122.525334766 0.11593724883253896 0.029934868780347262 3.00065828153866e-09 8.522783459720817 0.16213198722074684 DSSSSLTDPQVS(ph)YVKSPAAER ddPTM_PC-9_AZD4547_30min_R2 1 DSSSSLTDPQVSYVKSPAAER 21 1 H7C3M7;O94887-3;O94887-2;O94887 H7C3M7;O94887-3 FARP2 FERM, RhoGEF and pleckstrin domain-containing protein 2 1 DSSSSLTDPQVS(0.462)Y(0.376)VKS(0.161)PAAER 69.081 0.0014916999999999999 48983000.0 33112.0 37304.0 46366.0 58163.0 47330.0 58117.0 51921.0 59702.0 54723.0 53360.0 True False 43640.92722761447 49361.78848052041 45751.15654499379 44754.41895939219 40759.046475268675 54482.93480269159 56541.86841569527 50476.42771547835 57615.546060781286 51491.88264151993 0.8475302317345274 0.9586324280308612 0.8885120177777853 0.8691548388503656 0.7915625606278193 1.0580878384656276 1.098073434396111 0.9802793202744003 1.1189248305775406 1.0 15.652057398333712 -6.7784743141992685 24.985123442908595 1.052778125370979 0.8768042009946447 0.7325123389125001 0.05432441137333348 128.68364310429047 188738.94563877047 0.018978849192680797 0.016778737194234086 1.6654273244760389e-07 6.7784743141992685 -0.1759739243763342 DSSSSLTDPQVSYVKS(ph)PAAER ddPTM_PC-9_AZD4547_30min_R2 2 DSSSSLTDPQVSYVKSPAAER 21 1 H7C3M7;O94887-3;O94887-2;O94887 H7C3M7;O94887-3 FARP2 FERM, RhoGEF and pleckstrin domain-containing protein 2 1 DSSSSLTDPQVS(0.001)Y(0.001)VKS(0.998)PAAER;DSSSSLTDPQVS(0.025)Y(0.021)VKS(0.953)PAAER 79.383 0.00046825 36943000.0 100192.0 92257.0 138537.0 193179.0 150545.0 175809.0 170438.0 230900.0 172486.0 195536.0 True False 132050.97187693734 122077.27106603519 136699.9088615321 148644.5661357979 129644.42534585515 164815.63543758975 185606.6518178437 195219.71055415116 181603.2578228518 188690.344156526 0.6998289841868957 0.6469714791805528 0.724466900903706 0.7877698607221334 0.6870750378106791 0.8734714867066475 0.9836573919430437 1.0346036063838475 0.9624406518237352 1.0 17.525661072288152 -6.988363504196062 2.3510000098528208 1.000211262475849 0.7089001040123466 0.9239397704958976 0.03866868679198413 0.0790719702474738 0.8793312087474731 0.01712802134458245 0.013664596585797481 1.0271562091574154e-07 6.988363504196062 -0.2913111584635024 DSSSSLTDPQVSYVKS(ph)PAAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DSSSSLTDPQVSYVKSPAAER 21 1 H7C3M7;O94887-3;O94887-2;O94887 H7C3M7;O94887-3 FARP2 FERM, RhoGEF and pleckstrin domain-containing protein 2 1 DSSSSLTDPQVS(0.171)Y(0.037)VKS(0.792)PAAER;DSSSSLTDPQVS(0.008)Y(0.017)VKS(0.975)PAAER;DSSSSLTDPQVS(0.012)Y(0.038)VKS(0.95)PAAER;DSSSS(0.001)LT(0.001)DPQVS(0.156)Y(0.128)VKS(0.714)PAAER 101.42 8.036e-05 102861000.0 185280.0 173361.0 250987.0 300927.0 361676.0 298272.0 328488.0 319613.0 269076.0 252188.0 True False 216644.24455319374 190571.13437706456 256971.48195349766 284067.0358084981 290808.18411289 282630.0912421532 297371.2385928291 311223.4974079655 273010.72745822073 297907.688080891 0.7272193811069698 0.6396986113541276 0.8625876143341494 0.9535404663050028 0.9761687789471439 0.9487170105036381 0.9981992761196675 1.0446977700134374 0.9164272638176764 1.0 18.18450583002511 -5.4938136431170905 2.519453682290018 0.9795144001336651 0.681207568688309 0.8950168254897498 0.03974247883258696 0.07849559219152498 0.9800105371931882 0.010979549089452702 0.026101643695696303 3.2076454381724422e-06 5.4938136431170905 -0.2983068314453561 DSSSSLTDPQVSYVKS(ph)PAAER ddPTM_PC-9_Lapatinib_30min_R1 3 DSSSSLTDPQVSYVKSPAAER 21 1 H7C3M7;O94887-3;O94887-2;O94887 H7C3M7;O94887-3 FARP2 FERM, RhoGEF and pleckstrin domain-containing protein 2 1 DSSSSLTDPQVS(0.016)Y(0.002)VKS(0.981)PAAER;DSSSSLTDPQVS(0.068)Y(0.054)VKS(0.878)PAAER;DSSSSLTDPQVS(0.049)Y(0.012)VKS(0.938)PAAER 85.182 0.00021755 94477000.0 194092.0 193261.0 226879.0 208458.0 214503.0 221422.0 182401.0 163314.0 229314.0 191130.0 True False 191324.21248788686 192813.51602842088 208225.88439826673 223788.69671550277 201886.35526912406 211952.2972198923 191844.83128505238 170902.16464706845 203486.2425365278 224166.56583528392 0.8534912946316473 0.8601350308863587 0.9288891214547566 0.9983143377408975 0.9006086813921608 0.9455125318538065 0.8558137587119868 0.7623891815010727 0.9077457281745045 1.0 17.774211592452716 -8.554117408927915 22.791112808068153 1.0000000026409075 0.8898396975643561 0.23583528887611382 0.060093271450762625 6449.660923178111 4705537.597201578 0.06378514831534707 0.01646925449432633 2.7917889956719086e-09 8.554117408927915 -0.11016030507655139 DSSST(ph)DSANEKPALIPR ddPTM_PC-9_AZD4547_30min_R2 1 DSSSTDSANEKPALIPR 17 1 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;Q9NUQ6-2;F8VT91;F2Z2S1;C9JKE4;F8VZ02;C9JGM8;C9JW67;F8W6C2 B8ZZZ7 SPATS2L SPATS2-like protein 1 DS(0.002)S(0.013)S(0.075)T(0.455)DS(0.455)ANEKPALIPR 102.15 0.010212 5353100.0 23363.0 29381.0 36208.0 35662.0 37987.0 34589.0 37072.0 42956.0 29799.0 29886.0 True False 30791.948019411597 38877.83367322997 35727.85826211308 27440.676872407617 32713.16075334949 32426.144362067877 40371.33618201988 36318.13723068051 31374.114304135783 28839.70023659043 1.067693067778293 1.3480664970263332 1.2388429133803298 0.9514896703951243 1.134310013106329 1.1243578850007303 1.3998528365700091 1.2593104967367796 1.0878793484937062 1.0 14.815768548655509 DSSSTDS(ph)ANEKPALIPR ddPTM_PC-9_Lapatinib_30min_R1 2 DSSSTDSANEKPALIPR 17 1 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;Q9NUQ6-2;F8VT91;F2Z2S1;C9JKE4;F8VZ02;C9JGM8;C9JW67;F8W6C2 B8ZZZ7 SPATS2L SPATS2-like protein 1 DS(0.003)S(0.047)S(0.047)T(0.179)DS(0.725)ANEKPALIPR;DS(0.044)S(0.19)S(0.19)T(0.019)DS(0.557)ANEKPALIPR 69.024 0.0078488 47351000.0 60717.0 82293.0 68454.0 64930.0 77013.0 76512.0 85293.0 81913.0 77990.0 48759.0 True False 59851.164445865885 82102.45561456673 62825.97636008151 69705.16880013046 72483.24675338352 73239.76011818335 89709.05419814588 85718.97701810826 69205.94492889136 57186.92818271643 1.0465882037698724 1.435685710416957 1.0986072929000121 1.2189003853715892 1.2674792834088626 1.2807080646852886 1.5686986003430516 1.498926061288514 1.210170700335106 1.0 15.803397792267 -6.834521668563628 3.0239193612313446 1.3659323824947185 1.216568706456268 0.045916449614325616 0.17663880756529668 0.5394102560435239 9.973477912807608 0.06419130582749843 0.057239591244786225 1.4637885018872712e-07 6.834521668563628 -0.14936367603845047 DSTLIMQLLR ddPTM_PC-9_AZD4547_30min_R2 3 DSTLIMQLLR 10 0 P31947-2;P31947;P63104;E7EX29;B0AZS6;P63104-2;B7Z2E6;H0YB80;P62258;P62258-2;K7EM20;P27348;P31946-2;P31946;P61981;Q04917 P31947-2;P63104;P62258;P27348;P31946-2;P61981;Q04917 SFN;YWHAZ;YWHAE;YWHAQ;YWHAB;YWHAG;YWHAH 14-3-3 protein sigma;14-3-3 protein zeta/delta;14-3-3 protein epsilon;14-3-3 protein theta;14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed;14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed;14-3-3 protein eta 0 ;; 148.69 0.00070397 25189700.0 50723.1 53891.1 62229.4 51134.7 56496.8 71038.5 62754.5 84280.3 73255.7 60288.8 False True 66851.99069397844 71310.3441771011 61404.19749603235 39346.38493823964 48653.19452575452 66596.45136502251 68339.52892842484 71256.71620362523 77127.84674752432 58178.10746248252 1.1490918768213536 1.22572471480079 1.0554519590660498 0.6763091247616305 0.8362801171751701 1.1446995144688876 1.1746605709457831 1.2248029252167878 1.3257194176909584 1.0 15.828188745790007 -6.948391844667975 9.602158672386068 1.1943301836187552 0.9880316791171909 0.24673899743914496 0.16233650137109726 0.5724374974991264 101.54850321335115 0.06422451128066053 0.05660409086845101 1.1261808945237464e-07 6.948391844667975 -0.20629850450156428 DSTLIMQLLR ddPTM_PC-9_Lapatinib_30min_R1 2 DSTLIMQLLR 10 0 P31947-2;P31947;P63104;E7EX29;B0AZS6;P63104-2;B7Z2E6;H0YB80;P62258;P62258-2;K7EM20;P27348;P31946-2;P31946;P61981;Q04917 P31947-2;P63104;P62258;P27348;P31946-2;P61981;Q04917 SFN;YWHAZ;YWHAE;YWHAQ;YWHAB;YWHAG;YWHAH 14-3-3 protein sigma;14-3-3 protein zeta/delta;14-3-3 protein epsilon;14-3-3 protein theta;14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed;14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed;14-3-3 protein eta 0 ; 160.82 0.0025305999999999996 183152000.0 392780.0 430750.0 527320.0 418520.0 388230.0 391300.0 387950.0 434130.0 430180.0 431550.0 False True 387178.8851729694 429752.6248402021 483965.78511406557 449299.3569417921 365395.07468954724 374565.01116485195 408036.15274607175 454301.2646694832 381728.59840377606 506142.8424957693 0.7649597162409854 0.8490737964822535 0.9561841924458526 0.8876927997762759 0.7219208571394575 0.7400381467766836 0.8061679796439725 0.8975752031370088 0.7541914383723934 1.0 18.949185070973158 -10.846790949503637 4.316748456588712 1.0002058700258893 0.8232960401599636 0.35178771114974106 0.07325901867543648 0.00016251757150445535 2.54535838022965e-05 0.07670086109414649 0.01858036035818883 1.4230135992163271e-11 10.846790949503637 -0.17690982986592574 DSVDSAGT(ph)SPTAVLAAGEEVGAGGGPGGGRPGAGTPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSVDSAGTSPTAVLAAGEEVGAGGGPGGGRPGAGTPLR 38 1 Q5T0D9-2;Q5T0D9 Q5T0D9-2 TPRG1L Tumor protein p63-regulated gene 1-like protein 1 DS(0.001)VDS(0.022)AGT(0.442)S(0.4)PT(0.134)AVLAAGEEVGAGGGPGGGRPGAGT(0.001)PLR 45.993 0.0043331 3737600.0 1336.2 1734.0 1246.2 1542.0 3349.1 3105.6 2811.8 3237.3 3162.5 2517.9 True False 1562.3922688470263 1906.1400603932275 1275.9141342398182 1455.6067392314521 2692.867896715512 2942.7368689036575 2545.4459483308856 3152.324305202879 3208.7455796378053 2974.3753383145668 0.5252841659628464 0.6408539083279732 0.42896877129260236 0.48938233197437464 0.9053557774054933 0.9893629869090976 0.8557917743405126 1.0598273407515364 1.0787964579668834 1.0 11.53837099814442 -6.335846903372021 4.066385069997877 0.9871391578965919 0.5219780051516167 0.900385123497514 0.07536490630417324 0.07216260131960556 2.2936316816529727 0.025591719752502563 0.02966629690438407 4.614802259823909e-07 6.335846903372021 -0.46516115274497516 DSVDSAGT(ph)SPTAVLAAGEEVGAGGGPGGGRPGAGTPLR ddPTM_PC-9_Lapatinib_30min_R1 2 DSVDSAGTSPTAVLAAGEEVGAGGGPGGGRPGAGTPLR 38 1 Q5T0D9-2;Q5T0D9 Q5T0D9-2 TPRG1L Tumor protein p63-regulated gene 1-like protein 1 DSVDS(0.058)AGT(0.409)S(0.409)PT(0.123)AVLAAGEEVGAGGGPGGGRPGAGTPLR;DS(0.003)VDS(0.02)AGT(0.417)S(0.417)PT(0.142)AVLAAGEEVGAGGGPGGGRPGAGTPLR 67.083 2.5383000000000003e-06 7263200.0 9487.0 6002.0 5257.7 6096.299999999999 8373.0 10062.7 5986.200000000001 9588.2 11947.7 4866.3 True False 9351.713640297272 5988.102737761782 4825.432201308915 6544.642238660633 7880.516601951365 9632.341778299393 6296.136145298446 10033.702775445003 10602.024211141377 5707.433471062837 1.6385146997702624 1.049176090815944 0.8454644676585821 1.1466874334746981 1.3807461167802026 1.6876835844230453 1.1031466555362195 1.7580060856279291 1.8575817422830283 1.0 12.478626422374942 -6.385231579557933 3.7259839342140544 1.5071698649872518 1.1384081034584776 0.17365277435176152 0.3138532085865769 0.3778103785444742 9.360197600702461 0.10163581171474283 0.11611851354103497 4.11877834238895e-07 6.385231579557933 -0.36876176152877416 DSVDSAGTS(ph)PTAVLAAGEEVGAGGGPGGGRPGAGTPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSVDSAGTSPTAVLAAGEEVGAGGGPGGGRPGAGTPLR 38 1 Q5T0D9-2;Q5T0D9 Q5T0D9-2 TPRG1L Tumor protein p63-regulated gene 1-like protein 1 DSVDS(0.006)AGT(0.14)S(0.426)PT(0.426)AVLAAGEEVGAGGGPGGGRPGAGTPLR 55.483999999999995 0.00010802 3490000.0 3577.1 2570.3 2741.5 2380.7 3601.2 3518.5 2210.9 2989.3 3459.7 2702.6 True False 4182.632379054557 2825.462397479074 2806.8677571966464 2247.3170973335386 2895.5707114305023 3333.9836660347496 2001.4675464701472 2910.834042425159 3510.291567390645 3192.5599862301724 1.310118649953224 0.8850146621098971 0.8791902953438449 0.7039232174262786 0.9069745670932999 1.044297892730145 0.6269161911139258 0.9117554736574645 1.0995225093751975 1.0 11.640498012193454 -4.761440145081618 9.371999495737436 0.8825267235211436 1.3126030878128572 0.45232527365556385 0.13629239101420978 0.07055800344323704 99.95820922414913 0.033739342258839164 0.19217404736979893 1.7320477269249773e-05 4.761440145081618 0.4300763642917136 DSVDSAGTSPT(ph)AVLAAGEEVGAGGGPGGGRPGAGTPLR ddPTM_PC-9_AZD4547_30min_R2 2 DSVDSAGTSPTAVLAAGEEVGAGGGPGGGRPGAGTPLR 38 1 Q5T0D9-2;Q5T0D9 Q5T0D9-2 TPRG1L Tumor protein p63-regulated gene 1-like protein 1 DS(0.004)VDS(0.033)AGT(0.287)S(0.123)PT(0.549)AVLAAGEEVGAGGGPGGGRPGAGT(0.004)PLR;DSVDS(0.001)AGT(0.022)S(0.069)PT(0.908)AVLAAGEEVGAGGGPGGGRPGAGTPLR 98.446 1.1821e-12 6463000.0 8894.8 8891.099999999999 12699.0 14731.7 11271.5 10456.1 10131.4 12514.4 10579.400000000001 12529.0 True False 11723.161376666625 11764.97420006314 12530.602962620802 11335.534167496146 9706.64678525229 9802.278414068582 11033.07497287755 10580.587032303481 11138.605485726834 12090.363523530801 0.9696285272027172 0.9730868866900176 1.0364124236821488 0.9375676873101811 0.8028415991265095 0.810751338865118 0.9125511363992067 0.8751256330474327 0.9212796177756265 1.0 13.561570002607175 -6.0027061276319 20.487313681587324 0.8775674869806167 0.9903711148208164 0.41589744442245535 0.05570228593302146 9.483974829292412 71819.57505608906 0.015784820254476247 0.022788598246595345 9.93788283831881e-07 6.0027061276319 0.1128036278401997 DSVSS(ph)VSDISQYR ddPTM_PC-9_AZD4547_30min_R2 1 DSVSSVSDISQYR 13 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;F5H1B5;F5H2B8;F5GYM8;F5H3Q6;F5H0R8 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 DSVS(0.124)S(0.76)VS(0.116)DISQYR 214.61 2.3128e-14 11506000.0 131930.0 135620.0 174940.0 191100.0 153760.0 170390.0 138790.0 180870.0 150840.0 144450.0 True False 173880.99568552675 179456.5128063529 172620.18129623472 147044.8474655681 132413.07809079447 159735.48636424172 151142.04112814358 152920.69747912273 158813.09445403685 139392.84946715826 1.247416896563938 1.2874154843117247 1.2383718530476342 1.054895197477204 0.9499273355624439 1.1459374492654755 1.0842883383609536 1.0970483641282598 1.1393202381694199 1.0 17.088797030601107 -5.71545398032414 5.387384368704664 1.070312293241473 1.264587358405305 0.7033406668810719 0.056730733509642355 0.10773883560019182 7.064418478149855 0.016132198935258742 0.027795857916622424 1.925511069545698e-06 5.71545398032414 0.19427506516383186 DSVSS(ph)VSDISQYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSVSSVSDISQYR 13 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;F5H1B5;F5H2B8;F5GYM8;F5H3Q6;F5H0R8 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 DSVS(0.042)S(0.936)VS(0.022)DISQYR 151.3 0.00013282 4142300.0 28059.0 44693.0 28586.0 38863.0 43997.0 43559.0 42382.0 36513.0 37441.0 39241.0 True False 32808.83450948862 49129.82567425291 29267.598653008714 36685.632105546 35376.10368510718 41274.68935876297 38367.27014089185 35554.57243872139 37988.50379358706 46355.082668414914 0.7077721065492493 1.0598584415367385 0.6313784156607891 0.7914047391084168 0.7631547965982053 0.890402669627562 0.8276820562555972 0.7670048329554011 0.8195110785439583 1.0 15.500439913405598 -6.7520977716731805 24.936225943250268 0.8442805536711717 0.7968526249964997 0.07183587247403489 0.11785190450535925 806.6424526334281 2153225.1532434593 0.03826113213513712 0.03775665328113593 1.769710502794234e-07 6.7520977716731805 -0.04742792867467205 DSVSS(ph)VSDISQYR ddPTM_PC-9_Lapatinib_30min_R1 2 DSVSSVSDISQYR 13 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;F5H1B5;F5H2B8;F5GYM8;F5H3Q6;F5H0R8 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 DSVS(0.017)S(0.954)VS(0.029)DISQYR;DSVS(0.126)S(0.869)VS(0.006)DISQYR 179.67 0.00010719 18022700.0 81522.0 78213.0 80589.0 70150.0 71524.0 89553.0 94214.0 88390.0 103793.0 86488.0 True False 80359.48133069623 78031.90260389235 73963.28350253598 75309.06501353986 67317.09894159438 85723.0269482391 99091.93992735761 92496.92208355948 92102.73935125572 101437.33556198407 0.7922081242127258 0.7692621476262096 0.7291524673116058 0.742419589358414 0.6636323654268279 0.8450835826208919 0.9768783789357983 0.9118626940574411 0.9079767212041528 1.0 16.630229230488162 -6.998849748856429 4.878598562481647 0.9393074603698859 0.7407608753881904 0.8545027256195122 0.04072151752404046 0.07039989112364023 4.718841450214707 0.015523861885536743 0.012892213743295564 1.0026520616465175e-07 6.998849748856429 -0.19854658498169553 DSVSSVS(ph)DISQYR ddPTM_PC-9_AZD4547_30min_R2 1 DSVSSVSDISQYR 13 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;F5H1B5;F5H2B8;F5GYM8;F5H3Q6;F5H0R8 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 DSVS(0.002)S(0.081)VS(0.917)DISQYR 206.46 7.3201e-10 9918600.0 144750.0 149590.0 200650.0 219180.0 178780.0 160590.0 147700.0 184520.0 145650.0 156540.0 True False 190777.4890129615 197942.04210811298 197989.24989761898 168651.43729724342 153959.48296743145 150548.2819134544 160845.0138671868 156006.67384777864 153348.76164963187 151059.58224706742 1.2629287475516313 1.3103574044337443 1.3106699154893409 1.1164563994451104 1.0191970656692342 0.9966152406487081 1.0647786222797484 1.032749273678117 1.0151541489027842 1.0 17.204758176687733 -5.909058375661254 3.084944797482367 1.02527679509214 1.2978872721929138 0.9641032715087952 0.023509345414174734 0.04353745764008516 0.8319165960929907 0.007351478674390759 0.011559401019128055 1.2329390966712607e-06 5.909058375661254 0.2726104771007738 DSYESYGNSR ddPTM_PC-9_AZD4547_30min_R2 3 DSYESYGNSR 10 0 P38159;P38159-2;H3BUY5;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 0 ;; 134.23 0.00051186 38227000.0 67707.0 70873.0 88789.0 113290.0 115143.0 92434.0 83735.0 100703.0 76150.0 80508.0 False True 89236.4176069125 93781.31125294669 87611.59984629805 87172.74081305186 99157.38196285383 86654.0873677582 91187.25278381103 85141.66527472822 80175.13353669376 77689.43942472816 1.1486299588166289 1.2071307496536854 1.1277156907687986 1.1220668015954973 1.2763302541129231 1.1153908177148804 1.1737406455630388 1.0959232799873706 1.0319952638398677 1.0 16.24543088133501 -8.111240703638162 1.63695910473015 1.0009657473603704 1.1695962053798183 0.6441388523815659 0.04526234129921586 0.23300756021535093 1.117498303688817 0.04035642439816425 0.012730529636964928 7.740326785526528e-09 8.111240703638162 0.16863045801944798 DSYESYGNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DSYESYGNSR 10 0 P38159;P38159-2;H3BUY5;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 0 ;; 157.99 0.00056449 30644900.0 61098.0 80768.0 72265.0 82832.0 103161.0 86007.0 66784.0 72913.0 80927.0 69445.0 False True 71440.68465949378 88786.11326288347 73988.0716665387 78191.19158496718 82947.34259743484 81496.64151332964 60457.73604571095 70999.11100770933 82110.40427615773 82034.8287736824 0.8708579724909803 1.0822977824190565 0.9019104784219995 0.9531462764514442 1.0111234927578123 0.9934395272301048 0.7369764397570902 0.8654752142359144 1.0009212611716887 1.0 16.32394893112218 DSYESYGNSR ddPTM_PC-9_Lapatinib_30min_R1 2 DSYESYGNSR 10 0 P38159;P38159-2;H3BUY5;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 0 ; 150.81 0.00074871 27337000.0 72721.0 68653.0 83651.0 71870.0 67813.0 64240.0 64737.0 57565.0 63154.0 57706.0 False True 71683.98520460183 68494.03819652775 76773.53768219784 77155.55955129181 63824.3726654877 61492.604950754125 68088.76509942625 60239.68005136433 56040.9314788974 67680.40521158818 1.0591541965580338 1.0120216919859732 1.1343539897874717 1.1399984871556488 0.9430258649598001 0.9085732385689886 1.0060336501615412 0.8900608656676622 0.8280229898697787 1.0 16.046450585640272 -6.341735991071721 6.264871281368509 0.9253511198415048 1.0841610080659676 0.6305086897519874 0.05892714804522363 0.16313378013203284 10.352653682915452 0.01923915630005614 0.0218783382423444 4.5526473285366027e-07 6.341735991071721 0.15880988822446285 DSYETSQLDDQS(ph)AETHSHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSYETSQLDDQSAETHSHK 19 0 P10451-4;P10451;P10451-3;P10451-5;P10451-2;D6R9C5 P10451-4 SPP1 Osteopontin 1 DS(0.001)YET(0.006)S(0.002)QLDDQS(0.94)AET(0.041)HS(0.01)HK 62.871 0.044716000000000006 0.0 12104.0 13621.0 13159.0 14608.0 19733.0 13086.0 16752.0 12811.0 11437.0 8250.3 True False 14152.968135102838 14973.202861947042 13472.760465785408 13789.561119774995 15866.460304525763 12399.747123413586 15165.129286022844 12474.724824376519 11604.244488321763 9746.014080661133 1.452180144412715 1.5363411891286038 1.3823867228469535 1.414892386328213 1.6279948062058867 1.2722890630763828 1.5560340012349028 1.2799822287482556 1.1906656805829872 1.0 13.250596591543363 -8.310981246800788 1.3503856095741584 1.0058882181528206 1.4631997353643353 0.7027575864458806 0.09820505512027235 0.21043537862715678 0.7719571641454115 0.08698483637448459 0.027040319121303138 4.88673460216262e-09 8.310981246800788 0.45731151721151475 DSYETSQLDDQS(ph)AETHSHK ddPTM_PC-9_Lapatinib_30min_R1 1 DSYETSQLDDQSAETHSHK 19 0 P10451-4;P10451;P10451-3;P10451-5;P10451-2;D6R9C5 P10451-4 SPP1 Osteopontin 1 DSYETSQLDDQS(0.932)AET(0.041)HS(0.027)HK 81.60600000000001 0.0018215 6350100.0 18572.0 36458.0 31891.0 34825.0 33066.0 31412.0 17979.0 23133.0 32694.0 22829.0 True False 18307.159874312314 36373.58374097286 29269.04508281999 37386.1466727944 31121.122890257255 30068.581984948447 18909.86464807736 24207.843631168435 29011.657436917263 26774.96223226961 0.6837417627520772 1.358492438773073 1.0931498176884251 1.3963099685621974 1.16232182216674 1.1230111820180018 0.7062517767172382 0.9041224193396904 1.0835368201547622 1.0 14.708596919516362 -7.053699909672374 13.781152090276406 0.9153181031669876 1.1607710650560696 0.20718465450538903 0.20149614841720637 3.811614078953965 976.6465488539967 0.07474317153775464 0.0579278179099178 8.836903049375733e-08 7.053699909672374 0.24545296188908206 DSYETSQLDDQSAETHS(ph)HK ddPTM_PC-9_Lapatinib_30min_R1 1 DSYETSQLDDQSAETHSHK 19 0 P10451-4;P10451;P10451-3;P10451-5;P10451-2;D6R9C5 P10451-4 SPP1 Osteopontin 1 DSYETSQLDDQS(0.127)AET(0.09)HS(0.783)HK 72.184 0.0049901 6863400.0 28112.0 47123.0 35082.0 36103.0 42951.0 34044.0 31392.0 31913.0 42051.0 25872.0 True False 27711.117724890577 47013.88958872849 32197.69338043621 38758.13505607744 40424.706624914965 32588.017480440107 33017.324157764335 33395.79448413431 37314.77356333905 30343.940727726967 0.9132339788539519 1.549366643264276 1.0610913615124276 1.2772940536580322 1.3322167673487655 1.0739546907519035 1.0881027106540102 1.100575392754399 1.229727341552656 1.0 14.889120838211655 -6.77946667337226 24.973338212905045 1.104109881767467 1.238186708713812 0.1288993767678881 0.16491141046919386 482.1665112673183 667944.2482356381 0.05434845438416991 0.04802641313540699 1.6616261817411312e-07 6.77946667337226 0.13407682694634504 DSYGGPPR ddPTM_PC-9_Lapatinib_30min_R1 1 DSYGGPPR 8 0 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 0 92.47 0.036631 4616400.0 34288.0 32643.0 39070.0 36732.0 45945.0 38609.0 39030.0 37107.0 34887.0 27906.0 False True 33799.046832350905 32567.417139079935 35857.81541456135 39433.393814359944 43242.605431345444 36957.78307197486 41050.782424743295 38831.126685763535 30957.658683603477 32729.514917592343 1.0326779030319109 0.9950473516359608 1.0955804112846024 1.2048267111091286 1.3212113146260607 1.129188231632171 1.2542435330344053 1.1864253651034569 0.9458636573609442 1.0 14.998304599983761 -5.498275693918748 3.9648969895925545 1.1669936879570375 1.016645302445648 0.18956056239387276 0.10599803289824192 0.30224719381949394 10.486843319156232 0.028879623164496406 0.05973297023595459 3.1748580033032277e-06 5.498275693918748 -0.1503483855113894 DSYGGPPRR ddPTM_PC-9_AZD4547_30min_R2 1 DSYGGPPRR 9 1 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 0 68.22399999999999 0.027611 1416100.0 5920.4 5525.4 8514.8 11376.0 8584.4 9016.1 7320.7 9152.8 7428.2 8685.7 False True 7802.964048029979 7311.377494913888 8401.888188528517 8753.438957447961 7392.604237530037 8452.32184170807 7972.228117924936 7738.445070420259 7820.839487029142 8381.61628672132 0.9309617359114758 0.8723111682524799 1.002418614872565 1.0443616908728814 0.8820022278091949 1.0084357900156757 0.9511564172360213 0.9232640585897479 0.9330944318483542 1.0 13.033012760566834 -5.2574931911382015 24.98620089435455 0.9658364241801112 0.9016364526242105 0.23928585909455646 0.047259281157389484 489.493719282321 3099310.3014462804 0.012228294846288543 0.029915777327034293 5.527220734441516e-06 5.2574931911382015 -0.06419997155590063 DSYGGPPRR ddPTM_PC-9_Lapatinib_30min_R1 2 DSYGGPPRR 9 1 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 0 ; 78.113 0.013969 3451300.0 23781.0 22374.6 25849.0 21603.0 21875.0 19547.2 16763.4 19207.4 23212.0 18213.7 False True 23441.878579098702 22322.792988391324 23723.795000025526 23191.75668549542 20588.355507904715 18711.211822748766 17631.326828053843 20099.84592406107 20597.620126803788 21361.91377677028 1.0973679055193195 1.0449809516910389 1.110565057416515 1.085659128102791 0.9637879697039708 0.8759145841650207 0.8253626998170355 0.9409197197452585 0.9642216676860846 1.0 14.382753280908986 -6.3775723468231895 3.4153738684913715 0.9120912067925395 1.0842517599660086 0.7224226174113372 0.04777020984638263 0.13253773755438647 2.869241466191406 0.01613815954654138 0.018560553837913312 4.1920615752874935e-07 6.3775723468231895 0.17216055317346912 DSYLILETLPTEYDSR ddPTM_PC-9_Lapatinib_30min_R1 4 DSYLILETLPTEYDSR 16 0 E9PM69;P17980;E9PKD5;R4GNH3;E9PLG2;E9PN50;E9PMD8 E9PM69 PSMC3 26S protease regulatory subunit 6A 0 ;;; 173.72 6.4093e-05 11122700.0 50258.1 48506.6 59200.5 47232.4 52974.0 53195.5 45076.1 50560.3 47196.6 49503.5 False True 49541.41027779321 48394.28594793662 54333.26341053855 50706.02825866746 49858.17347089117 50920.45246976712 47409.91989894877 52909.516117449806 41880.82190576893 58060.11401573249 0.8532778675627304 0.8335203395367649 0.9358104842132401 0.8733366979769915 0.8587336472915149 0.8770298393828379 0.8165660833201628 0.9112885328319019 0.7213355091659056 1.0 15.825259784613754 DSYS(ph)SSR ddPTM_PC-9_AZD4547_30min_R2 2 DSYSSSR 7 0 P38159;P38159-2;H3BUY5;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 DS(0.011)YS(0.937)S(0.051)S(0.001)R;DS(0.001)YS(0.777)S(0.222)SR 82.75 0.022022999999999997 39947000.0 35074.0 32402.0 32993.7 32071.0 23672.1 30849.0 30700.0 24686.7 46815.0 66913.0 True False 46226.80241547925 42875.31284435513 32556.18198029939 24677.526442010672 20385.637525189268 28920.00715329823 33432.24052621953 20871.937758931017 49289.545325283274 64570.39623673213 0.7159132529712158 0.6640088235971622 0.5041967198240479 0.38218019216633486 0.3157118232703751 0.44788337750429535 0.5177642151001847 0.3232431419873742 0.7633458705220699 1.0 15.978585259771068 -8.504125818218965 4.613058775334644 0.9991403302218335 0.48275387545344906 0.6449431445996935 0.12424601082275652 0.10806407128614084 6.807531082507013 0.1313972449292373 0.03426385052182105 3.132378120497299e-09 8.504125818218965 -0.5163864547683844 DSYS(ph)SSR ddPTM_PC-9_Lapatinib_30min_R1 1 DSYSSSR 7 0 P38159;P38159-2;H3BUY5;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 DSYS(0.775)S(0.224)SR 78.264 0.028586 21284000.0 2425.3 7599.2 7314.8 10779.0 9641.7 8173.8 17044.0 14429.0 11753.0 3466.7 True False 2390.7147772544527 7581.60451929346 6713.40537994455 11571.723617689911 9074.594162311532 7824.225628058431 17926.45492306752 15099.424015654233 10429.253375423266 4065.9144759126107 0.5879894403626991 1.8646738794454694 1.6511427920376263 2.8460322238068207 2.231870398669589 1.9243458450518076 4.408960156261982 3.7136600155036725 2.5650449455364845 1.0 11.989364153933662 -5.036532864263094 0.6989214213026881 2.9349411728807357 2.4098804554021438e-14 0.30654996940660517 0.91931823868766 2.6685529690253573 1.2466489000285697 0.4205164317327579 5.869123493017338 9.193209046194441e-06 5.036532864263094 -2.9349411728807118 DSYS(ph)SSRSDLYSSGR ddPTM_PC-9_AZD4547_30min_R2 2 DSYSSSRSDLYSSGR 15 1 P38159;P38159-2;H3BUY5 P38159 RBMX RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed 1 DS(0.027)YS(0.704)S(0.009)S(0.123)RS(0.123)DLYS(0.01)S(0.003)GR;DS(0.006)Y(0.003)S(0.904)S(0.009)S(0.001)RS(0.06)DLYS(0.017)S(0.001)GR 137.39 0.000199 8940900.0 24427.1 23434.4 35614.0 59223.0 42928.0 44296.0 30369.7 37269.0 30832.1 34682.0 True False 32194.409684756625 31009.111515331 35141.73509022579 45570.052336228924 36968.18819121773 41526.164117556415 33072.54446609542 31509.93240642129 32461.821861020308 33467.79373637924 0.9619519571067975 0.9265358738489036 1.050016483519408 1.3616090948563073 1.1045899374906685 1.2407798507619519 0.9881901605645973 0.9415001375537412 0.9699420916932016 1.0 15.030485828378016 -10.413081752434309 5.159034802488019 0.9999998755665903 1.0661343617884365 0.016449005540237538 0.13444278874743976 2.109847060362078e-07 4.534758468465525e-08 0.14272793995420144 0.03461654461689972 3.8629425343112015e-11 10.413081752434309 0.06613448622184614 DSYS(ph)SSRSDLYSSGR ddPTM_PC-9_Lapatinib_30min_R1 2 DSYSSSRSDLYSSGR 15 1 P38159;P38159-2;H3BUY5 P38159 RBMX RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed 1 DS(0.004)YS(0.956)S(0.003)S(0.011)RS(0.003)DLYS(0.018)S(0.006)GR;DS(0.021)Y(0.001)S(0.94)S(0.011)S(0.008)RS(0.012)DLYS(0.006)S(0.001)GR 127.05 0.00010559 15635100.0 65218.0 44982.0 65862.0 53151.0 48132.0 53352.0 41848.0 43632.0 56748.0 44777.7 True False 64287.97936048355 44877.84694268586 60447.08059467216 57059.9018465383 45300.97039115291 51070.25932958643 44014.68467616339 45659.30200644715 50356.44265706796 52517.465782465224 1.2241256961402796 0.8545318452450895 1.1509900505300945 1.0864938167977962 0.8625886591481001 0.9724433303984368 0.8380961270766272 0.8694117533312525 0.9588513441537996 1.0 15.680509680561652 -6.255131247433928 24.746309161424282 0.909206241875915 1.0681390168391087 0.3821080000046214 0.10034021502217767 474.6948184157585 1862188.3333381228 0.02853794812269654 0.03591191189941963 5.557362837254644e-07 6.255131247433928 0.1589327749631937 DSYSSS(ph)RSDLYSSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSYSSSRSDLYSSGR 15 1 P38159;P38159-2;H3BUY5 P38159 RBMX RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed 1 DS(0.006)Y(0.075)S(0.162)S(0.125)S(0.47)RS(0.162)DLYSSGR 67.846 0.013683 12248000.0 20624.0 16297.0 21702.0 23773.0 26340.0 24510.0 25228.0 18005.0 22349.0 19113.0 True False 24115.235857432333 17914.858456879156 22219.457985293324 22441.075883105903 21178.86608327209 23224.652452610975 22838.221205096965 17532.387827874416 22675.811844845943 22578.035601575244 1.0680838795271383 0.7934640007224214 0.9841182987479697 0.9939339400076158 0.9380296167924576 1.0286391988411347 1.0115238370650619 0.7765240580385656 1.0043305912434595 1.0 14.462632349666155 -4.4637888941856465 22.834022372645947 0.9466472551381022 3.7820824111920013 0.15076335230695048 0.0855727277550462 778.0476919775156 334496.42987378046 0.02022909481051371 12494.291585554596 3.437249882689331e-05 4.4637888941856465 2.835435156053899 DSYSSSRSDLYS(ph)SGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DSYSSSRSDLYSSGR 15 1 P38159;P38159-2;H3BUY5 P38159 RBMX RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed 1 DSYS(0.031)SS(0.001)RS(0.003)DLYS(0.74)S(0.225)GR 137.39 0.000199 6409800.0 33317.0 28445.0 34224.0 48459.0 57916.0 50677.0 48041.0 49627.0 51494.0 40814.0 True False 38956.9100592549 31268.831613544065 35040.02995524279 45743.99933619775 46567.775553484724 48019.40890824013 43490.20869327981 48324.34383415292 52247.002332922995 48213.25511655375 0.8080124431565141 0.6485525928077834 0.7267717118567253 0.9487847112918082 0.9658708054643658 0.99597940010802 0.9020384246644175 1.0023041115421603 1.0836646935913745 1.0 15.557142216086685 -5.791157839580766 4.173804098722526 0.9848858995937275 0.7164207687522675 0.8204353828668176 0.05543809452232428 0.08074956322585397 3.0999372116468247 0.015936594597040978 0.02581580729442491 1.6174920709973625e-06 5.791157839580766 -0.26846513084146006 DSYVGDEAQSK ddPTM_PC-9_AZD4547_30min_R2 4 DSYVGDEAQSK 11 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5;P63261;I3L3I0;I3L1U9;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTG1;ACTA1;ACTC1;ACTG2;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle 0 ;;; 175.33 0.00035475 333630000.0 310011.0 310213.0 334817.0 381027.0 357403.0 375488.0 335015.0 387748.0 326168.0 318399.0 False True 408588.0493706198 410483.28570415155 330377.10781445866 293187.1119584673 307783.7626748462 352008.67600173847 364830.68598994875 327830.4561626291 343408.5745948308 307251.9479231137 1.3298143498600838 1.3359826958912244 1.0752644858646487 0.9542237695815488 1.0017308751183756 1.1456678415911121 1.187399098544506 1.066976005778375 1.1176774530352689 1.0 18.229062631495637 -5.263550263807114 10.723754053194464 1.0714967083498408 1.333021418764829 0.7134722452830223 0.06697197290488534 0.060641709631650685 223.65637724714503 0.01927605343004347 0.0443329574168591 5.450668078084016e-06 5.263550263807114 0.26152471041498826 DSYVGDEAQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DSYVGDEAQSK 11 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5;P63261;I3L3I0;I3L1U9;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTG1;ACTA1;ACTC1;ACTG2;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle 0 ;;; 152.69 0.00035256 276402000.0 333636.0 410408.0 353412.0 359954.0 396625.0 281547.0 356915.0 293342.0 286259.0 259241.0 False True 390113.9851886287 451150.593948019 361838.68240247434 339786.9443666141 318909.17844638583 266782.17968483275 323105.42735917127 285642.083321541 290444.9963261782 306239.3411493732 1.2738859211375597 1.47319607028531 1.1815551883191313 1.1095470068977111 1.0413723372361643 0.8711558047491534 1.0550748514103265 0.9327413070099784 0.9484248341055205 1.0 18.224300105528187 -5.749399381876626 1.3991112846061866 0.9666628274639177 1.3806122778193604 0.8202900149541401 0.07265680505330535 0.16207649220753728 0.6341763513317162 0.02320257857703539 0.056353834624465214 1.7807404261966928e-06 5.749399381876626 0.4139494503554426 DSYVGDEAQSK ddPTM_PC-9_Lapatinib_30min_R1 5 DSYVGDEAQSK 11 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5;P63261;I3L3I0;I3L1U9;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTG1;ACTA1;ACTC1;ACTG2;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle 0 ;;;; 152.7 0.00035475 815371100.0 276850.0 343377.0 351214.0 302224.0 300964.0 282318.0 346246.0 294433.0 278970.0 263725.0 False True 272902.0682319286 342581.9316535208 322338.54064524535 324450.5611497085 283261.8892379901 270243.9172554016 364172.9236853103 308113.4320605112 247549.46091566692 309309.51485852635 0.882294449806208 1.1075699750465573 1.0421229388713706 1.048951117129738 0.915787829441813 0.8737006276027662 1.1773738155189881 0.9961330552713122 0.8003292786802644 1.0 18.238691688168146 -6.242154553187108 24.314575590875744 0.9668590599991976 1.0280363118876599 0.06635661223886236 0.10653301999896216 1815.167244213456 2288586.3217021 0.03218856712096267 0.041476542156881985 5.725922252606968e-07 6.242154553187108 0.061177251888462236 DSYVGDEAQSKR ddPTM_PC-9_AZD4547_30min_R2 4 DSYVGDEAQSKR 12 1 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5;P63261;I3L3I0;I3L1U9;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTG1;ACTA1;ACTC1;ACTG2;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle 0 ;;; 111.5 0.0024079 892720700.0 282857.0 216101.0 339562.0 553241.0 461098.0 300380.0 273795.0 396745.0 283685.0 339992.0 False True 372799.6422089069 285951.42216461874 335059.1860141308 425699.83493824385 397082.50183083495 281597.1911150358 298162.22458880366 335437.17654312105 298680.0099455941 328088.9835655113 1.1362760131641785 0.8715666678504043 1.0212448536761911 1.297513346263399 1.2102890426723132 0.8582951736287353 0.9087846271109801 1.02239695127143 0.9103628128554797 1.0 18.32372762689652 -6.767805781842408 24.999876152982697 0.9394187714959854 1.1000552597057207 0.3497018294458446 0.11392563859590489 208.79289108076577 819891.7313137469 0.044006416601451576 0.03973544248070177 1.7068455262156168e-07 6.767805781842408 0.1606364882097353 DSYVGDEAQSKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DSYVGDEAQSKR 12 1 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5;P63261;I3L3I0;I3L1U9;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTG1;ACTA1;ACTC1;ACTG2;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle 0 ;;;;; 194.48 1.3441e-36 547841400.0 386422.1 243935.30000000002 362293.19999999995 494170.0 495134.0 579111.0 516363.0 549675.8 514367.0 403019.1 False True 451835.7293456302 268151.5844717654 370931.64389261225 466483.25702075625 398116.0470491599 548741.3996933497 467449.35849562 535247.3926796518 521888.6442882397 476083.27253256046 0.9490686932604382 0.5632451294608883 0.7791318563229783 0.9798354278218258 0.8362319577651866 1.1526164252196447 0.9818646977638772 1.1242726295178644 1.0962129408832497 1.0 18.860854414277767 -6.2016177625597875 1.1246469708206464 1.0725154040100517 0.7420627328478165 0.5180364329247517 0.11797653378839873 0.3646558767722079 0.9529116114285768 0.04766747346340713 0.07585221715561183 6.28611377804262e-07 6.2016177625597875 -0.3304526711622352 DSYVGDEAQSKR ddPTM_PC-9_Lapatinib_30min_R1 5 DSYVGDEAQSKR 12 1 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5;P63261;I3L3I0;I3L1U9;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTG1;ACTA1;ACTC1;ACTG2;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle 0 ;;;; 163.46 0.00046365 977593000.0 696741.0 410059.0 463336.0 397880.0 355008.0 371048.0 289180.0 308552.0 454732.0 301972.0 False True 686805.3455733488 409109.5335794498 425242.30260868144 427141.42248877155 334127.12741258263 355179.14199513436 304152.3254313932 322888.45234445523 403515.293619754 354167.4578476023 1.939210761336746 1.155130220223364 1.2006814663126462 1.2060436751717878 0.9434156640002679 1.0028565135647425 0.8587811180615851 0.9116830052844482 1.139334754446542 1.0 18.434072132718875 -1.8731736925078308 0.8835010626668548 0.9926361991760234 199.99999936645364 0.8576146792697998 0.11034166243132422 143.98736809899034 0.6928398016493731 0.038329770683398504 57240.81672904506 0.013391410018765409 1.8731736925078308 199.00736316727762 DT(ph)CVQSPISSFPCTDLK ddPTM_PC-9_AZD4547_30min_R2 1 DTCVQSPISSFPCTDLK 17 0 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 DT(0.981)CVQS(0.019)PISSFPCTDLK 255.23 3.098e-57 30470000.0 104530.0 97110.0 108260.0 127900.0 122930.0 144220.0 124740.0 157430.0 130420.0 129020.0 True False 137768.3656409318 128498.90841044768 106824.40166417268 98414.63103530189 105863.29142625774 135201.9006012729 135841.6183466003 133102.81088150732 137313.73494229297 124503.04907063162 1.1065461181016911 1.0320944697310117 0.8580063095769671 0.7904596053665357 0.8502867376862442 1.0859324459160171 1.091070615222734 1.0690727004283807 1.1028945553324863 1.0 16.925821548659606 -6.776156169395996 24.817247972997727 1.0754409378964456 0.921818896622836 0.3873821819859494 0.08920144471487983 247.010768900857 416536.9697043417 0.03520553659644391 0.031180669478707977 1.6743406860297123e-07 6.776156169395996 -0.15362204127360957 DT(ph)PTSAGPNSFNK ddPTM_PC-9_AZD4547_30min_R2 1 DTPTSAGPNSFNK 13 0 Q8WW12;Q8WW12-3 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 1 DT(0.97)PT(0.024)S(0.007)AGPNSFNK 124.81 0.00036471 2443000.0 9189.2 10207.0 10707.0 12278.0 14290.0 13515.0 13027.0 18684.0 16874.0 13661.0 True False 12111.174452766207 13506.213141236118 10565.018184170483 9447.49679320904 12306.080163354942 12669.904913508562 14186.377763357075 15796.817115607484 17765.925191046255 13182.73254808479 0.9187150242629886 1.0245382049564773 0.8014285464439151 0.716656941855472 0.9334999491545317 0.9610985330464941 1.0761333214954814 1.1982961087913804 1.3476663602363168 1.0 13.68636182614465 -7.312894243409411 1.7113930790128054 1.2038206884581644 0.8750982325322968 0.5932732303298296 0.11024065202984445 0.2581448734859428 1.4719121614453512 0.0642261979063051 0.03777865958408715 4.865256668592315e-08 7.312894243409411 -0.3287224559258676 DT(ph)QSPSTCSEGLLGWSQK ddPTM_PC-9_Lapatinib_30min_R1 1 DTQSPSTCSEGLLGWSQK 18 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 DT(0.572)QS(0.369)PS(0.058)T(0.001)CSEGLLGWSQK 141.3 0.00040728 13214000.0 31996.0 45765.0 53873.0 50106.0 67832.0 71121.0 65526.0 64012.0 65858.0 56385.0 True False 31539.73117265223 45659.03395429319 49443.769895793856 53790.96238871611 63842.255122843075 68079.32062114855 68918.61565881966 66986.23120729491 58440.37852451504 66131.07212171017 0.4769275646190235 0.6904323866133691 0.7476632135162672 0.8133992185960203 0.9653896886072758 1.029460410015019 1.0421517971458136 1.0129312750897321 0.8837052938890682 1.0 16.01304067038953 -5.230562429887616 0.7345398926480473 1.0051055171983259 0.3731071299943628 0.9033123150193915 0.05443398712383108 0.5117278669600814 0.31734577933564195 0.025778715585503962 0.24150010893488896 5.8808157126517325e-06 5.230562429887616 -0.6319983872039631 down DT(ph)SPSSGSAVSSSK ddPTM_PC-9_AZD4547_30min_R2 1 DTSPSSGSAVSSSK 14 0 F8WF16;B7Z8L1;F8W6A0;F8W0Q9;Q8NEY8-5;Q8NEY8-6;Q8NEY8-9;Q8NEY8-8;Q8NEY8-2;Q8NEY8-3;Q8NEY8;Q8NEY8-7 F8WF16 PPHLN1 Periphilin-1 1 DT(0.929)S(0.069)PS(0.002)SGSAVSSSK 99.161 0.0055608 6734900.0 34237.0 25384.0 28891.0 49095.0 46514.0 45211.0 28234.0 49534.0 35003.0 37385.0 True False 45123.65382616078 33588.88158882506 28507.886462955958 37776.90626018878 40056.333990083425 42383.949022910485 30746.771303494555 41879.6584780829 36853.1871199592 36076.162529108406 1.2507886278024254 0.9310547251727105 0.7902139380804177 1.0471431441664039 1.1103269079066704 1.1748463819762587 0.8522738880191656 1.1608678845565097 1.0215384491137005 1.0 15.138758264853765 -4.749044552022471 24.962576433569147 1.0125146314327427 1.250789188662391 0.27004893019333476 0.11878347406580762 865.4148484266841 1742795.7793057966 0.030899233390094046 0.5294636437688885 1.7821959318163018e-05 4.749044552022471 0.2382745572296483 DT(ph)SPSSGSAVSSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 DTSPSSGSAVSSSK 14 0 F8WF16;B7Z8L1;F8W6A0;F8W0Q9;Q8NEY8-5;Q8NEY8-6;Q8NEY8-9;Q8NEY8-8;Q8NEY8-2;Q8NEY8-3;Q8NEY8;Q8NEY8-7 F8WF16 PPHLN1 Periphilin-1 1 DT(0.816)S(0.183)PSSGSAVSSSK;DT(0.909)S(0.09)PSSGSAVSSSK;DT(0.747)S(0.252)PS(0.001)SGSAVSSSK;DT(0.901)S(0.098)PSSGSAVSSSK;DT(0.699)S(0.289)PS(0.001)S(0.009)GS(0.001)AVSSSK 185.66 1.3867000000000001e-05 428843700.0 121912.0 125655.0 125695.0 144397.0 157828.0 139230.0 152091.0 125530.0 131553.0 107543.0 True False 142549.29372824362 138129.1979750354 128692.04550094216 136306.90423139036 126902.73637777797 131928.5336995929 137683.83943651515 122234.970510029 133476.71375117556 127039.69459008046 1.122084669584637 1.0872916407799744 1.0130065718135843 1.0729473545352297 0.9989219258378698 1.0384827681244613 1.083785976349992 0.9621793479939095 1.0506693532432163 1.0 16.954919823721866 -5.069025729949082 3.185307419976329 1.0291262116095714 1.1193637337121618 0.45259415957638705 0.034765268148732625 0.22314920142545114 4.243454517290159 0.008735680415261389 0.03462334810516095 8.53049573259651e-06 5.069025729949082 0.0902375221025904 DT(ph)SPSSGSAVSSSK ddPTM_PC-9_Lapatinib_30min_R1 4 DTSPSSGSAVSSSK 14 0 F8WF16;B7Z8L1;F8W6A0;F8W0Q9;Q8NEY8-5;Q8NEY8-6;Q8NEY8-9;Q8NEY8-8;Q8NEY8-2;Q8NEY8-3;Q8NEY8;Q8NEY8-7 F8WF16 PPHLN1 Periphilin-1 1 DT(0.731)S(0.268)PSSGSAVSSSK;DT(0.823)S(0.175)PS(0.002)SGSAVSSSK;DT(0.927)S(0.073)PSSGSAVSSSK;DT(0.488)S(0.488)PS(0.017)S(0.006)GS(0.002)AVSSSK 139.77 0.00026397 768011700.0 64013.8 59714.8 75872.7 58808.8 70683.0 72162.0 59261.7 64522.0 78908.7 56278.4 True False 63100.951473306835 59576.53404946635 69634.73948309175 63133.795332405825 66525.56490812474 69075.79947783805 62329.98085627491 67519.92766914146 70021.17126055153 66006.04645374576 0.9559874415069732 0.9025920692161901 1.0549751609784541 0.9564850301501896 1.007870770668609 1.0465071487995186 0.9443071385884795 1.0229354929848216 1.0608296515625943 1.0 16.01031056749448 -5.253024860109141 24.992846131693636 1.0092798846928772 0.9292897525337974 0.42184936938873363 0.038522946497975094 588.8612831084668 1749028.4950961103 0.009596829629904463 0.02451429927355835 5.5843822741232544e-06 5.253024860109141 -0.0799901321590798 DT(ph)SSVAVNLPVPS(ph)GVAFPAVFLRSR ddPTM_PC-9_AZD4547_30min_R2 1 DTSSVAVNLPVPSGVAFPAVFLRSR 25 1 H3BPM3;H3BRE8;Q9BWH6-2;Q9BWH6 H3BPM3 RPAP1 RNA polymerase II-associated protein 1 2 DT(0.46)S(0.46)S(0.081)VAVNLPVPS(0.862)GVAFPAVFLRS(0.138)R 53.778999999999996 0.011059999999999999 13031000.0 60709.0 52019.0 48008.0 40363.0 51680.0 53876.0 60451.0 41664.0 51282.0 51118.0 True False 80013.19917435506 68833.12446301192 47371.382552130046 31057.93395213361 44505.12406173436 50507.1252031215 65831.02189089567 35225.78614347408 53992.661825722025 49328.37437910828 1.622052220075643 1.3954063017362346 0.9603272588725918 0.6296160038326212 0.9022215838635728 1.023895999794237 1.3345467536586133 0.7141079872762444 1.0945558718551482 1.0 15.590130123524004 -5.136212555503272 3.1301833929297684 0.9481737797313791 1.5881884925721454 0.5983451222126985 0.1846615967361216 0.18033188452087293 3.238617675409069 0.050720679201224264 0.18064468279243634 7.30781331731616e-06 5.136212555503272 0.6400147128407664 DT(ph)TSPMELAALEK ddPTM_PC-9_Lapatinib_30min_R1 1 DTTSPMELAALEK 13 0 Q6VY07-2;Q6VY07 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 DT(0.543)T(0.394)S(0.063)PMELAALEK 85.271 0.031226 5302300.0 23715.0 31956.0 38500.0 28358.0 33973.0 35632.0 31074.0 31810.0 31232.0 23655.0 True False 23376.819751201634 31882.00784537078 35334.67861429776 30443.54191951483 31974.774933487857 34108.1024222489 32682.859673750285 33288.0087281143 27714.323272459773 27743.73523169377 0.8425981417417985 1.1491606151485165 1.2736092786068791 1.0973123000661018 1.1525043281468694 1.229398353805101 1.1780266572186062 1.1998387545915912 0.9989398702449988 1.0 14.759874415137022 -4.762002126371345 7.538278455589551 1.1555403359099985 0.8376794572408371 0.5168276851833404 0.08601247624170547 0.0733803000251478 30.421138338856856 0.020359942161528356 0.11971020602123515 1.7298078897938045e-05 4.762002126371345 -0.31786087866916135 DTAAVVS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 DTAAVVSR 8 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 DTAAVVS(1)R 72.848 0.031563 14400000.0 41790.0 58523.0 65308.0 69264.0 98512.0 80246.0 78966.0 91529.0 80889.0 79252.0 True False 55078.3507140012 77439.41527035955 64441.97324851088 53296.25491813255 84835.30924089732 75228.20493447343 85993.82102258819 77385.29617718015 85164.62740183357 76477.41160243125 0.7201910938137743 1.012578925564705 0.8426275405803907 0.6968888434037723 1.1092858330759767 0.9836656779853921 1.1244342508560319 1.0118712774886858 1.113591917108321 1.0 16.222746075311505 -6.275332524632111 24.998814838607775 1.0574259108394903 0.8337189728045497 0.6161924739251949 0.09210268898697152 552.7847697667146 994658.3993506116 0.027989591886691288 0.03189343568109615 5.304781194979967e-07 6.275332524632111 -0.22370693803494068 DTASLSTTPSES(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 DTASLSTTPSESPR 14 0 H0YJ30;G3V582;F5H039;Q9NQX3;Q9NQX3-2 H0YJ30 GPHN Gephyrin;Molybdopterin adenylyltransferase;Molybdopterin molybdenumtransferase 1 DTASLSTTPS(0.029)ES(0.971)PR 158.29 0.00041515 13971000.0 38139.0 42704.0 40907.0 38644.0 33917.0 38182.0 39115.0 27090.0 37997.0 27374.0 True False 37595.13086616399 42605.121511725956 37543.78436558642 41486.00867260495 31922.06874338762 36549.04486658924 41140.18330883511 28348.700296907165 33717.37773385162 32105.55942643775 1.1709850735447949 1.3270325224933537 1.1693857710721118 1.2921752311359116 0.9942847691699452 1.1384023676750652 1.2814037208446112 0.8829841561197981 1.050203713506596 1.0 14.970535516849942 -7.053243531336268 0.49374773652738463 0.9769538533277579 1.2602282259428346 0.3700141753940931 0.11056487950085006 1.0729566392152357 0.5633405675384502 0.10546525876945079 0.11210821472092547 8.846194189476174e-08 7.053243531336268 0.2832743726150767 DTCVQS(ph)PISSFPCTDLK ddPTM_PC-9_AZD4547_30min_R2 3 DTCVQSPISSFPCTDLK 17 0 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 DTCVQS(0.948)PIS(0.049)S(0.003)FPCTDLK;DT(0.022)CVQS(0.953)PIS(0.006)S(0.019)FPCTDLK;DT(0.125)CVQS(0.874)PISSFPCTDLK 256.71 1.0110999999999999e-57 91872000.0 142066.0 154211.0 159683.0 167160.0 176198.0 202576.0 190529.0 233418.0 211680.0 196974.0 True False 187240.03284362974 204056.68998953307 157565.4990849811 128623.8445962553 151735.94909886704 189908.8906961826 207485.71189641993 197348.61151203566 222868.97264671503 190078.00021421944 0.9850694590252881 1.0735418604970566 0.828951792987108 0.6766898034033143 0.7982825415243184 0.999110315145118 1.0915819382705092 1.0382506723009617 1.172513244013194 1.0 17.536232037362133 -6.959122209439101 4.78652643925054 1.0754648182742796 0.8710006476189324 0.4440601761344495 0.10764504754971631 0.21217979787390273 11.213361616576814 0.044662478577618965 0.0384120827939773 1.0986966252990864e-07 6.959122209439101 -0.20446417065534728 DTCVQS(ph)PISSFPCTDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DTCVQSPISSFPCTDLK 17 0 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 DT(0.009)CVQS(0.987)PIS(0.004)SFPCTDLK;DT(0.025)CVQS(0.974)PISSFPCTDLK;DTCVQS(0.602)PIS(0.236)S(0.153)FPCT(0.008)DLK;DT(0.005)CVQS(0.929)PIS(0.06)S(0.006)FPCTDLK 213.36 3.3103e-22 78137000.0 262940.0 323225.0 299524.0 299704.0 403579.0 316939.0 435887.0 354712.0 343621.0 312230.0 True False 307450.54869827646 355312.6418803927 306665.78811109526 282912.55653347773 324500.5920660917 300318.160900778 394596.627811404 345401.18584843096 348645.80705793574 368834.8273886797 0.8335724445411001 0.9633381001354373 0.8314447696880033 0.7670440411944701 0.8797992162603766 0.8142348243711309 1.0698464421191343 0.9364657570269136 0.9452627061449685 1.0 18.4926153637416 -7.247286513838866 24.995743852201475 0.982599209888292 0.8504511931548041 0.5788256484946923 0.058272172760793405 621.4901937674887 1097631.5448794675 0.02296515709687671 0.01769847135894246 5.658658514382504e-08 7.247286513838866 -0.13214801673348786 DTCVQS(ph)PISSFPCTDLK ddPTM_PC-9_Lapatinib_30min_R1 4 DTCVQSPISSFPCTDLK 17 0 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 DTCVQS(0.999)PISSFPCTDLK;DT(0.001)CVQS(0.999)PISSFPCTDLK;DT(0.001)CVQS(0.994)PIS(0.004)S(0.001)FPCTDLK;DTCVQS(0.979)PIS(0.019)S(0.002)FPCTDLK 236.27 2.3349e-37 119993000.0 83269.0 164657.0 161081.0 144342.0 255544.0 253726.0 279521.0 250956.0 245239.0 242225.0 True False 82081.5687903355 164275.74683299588 147837.5419706415 154957.39219079664 240513.4043388342 242874.7304441942 293993.2296732428 262616.33191992046 217617.60133884358 284093.26850547554 0.28892472258192026 0.5782458264400223 0.5203838258765083 0.5454454905108391 0.8466001521405235 0.8549119510007436 1.034847573896586 0.924401811072334 0.7660075949129688 1.0 18.11600512219509 -6.23535478748684 1.5453979468894499 0.9260743176991401 0.45599996023545974 0.8238970545588935 0.09654946379085935 0.15988868942761622 0.7608096048121912 0.035330392294925884 0.04925138827718485 5.816278753199332e-07 6.23535478748684 -0.4700743574636803 DTCYS(ph)PKPSVYLSTPSSASK ddPTM_PC-9_AZD4547_30min_R2 2 DTCYSPKPSVYLSTPSSASK 20 1 Q9Y5K6 Q9Y5K6 CD2AP CD2-associated protein 1 DT(0.058)CY(0.17)S(0.724)PKPS(0.04)VY(0.003)LS(0.002)T(0.002)PSSASK;DT(0.197)CY(0.159)S(0.625)PKPS(0.004)VY(0.012)LS(0.001)T(0.001)PSSASK 67.217 0.0026603 58728000.0 105827.0 100362.0 132791.0 176981.0 144065.0 133165.0 144204.0 154361.0 145950.0 148197.0 True False 139477.78466165575 132802.05381412164 131030.10457590209 136180.7647791928 124064.06149291327 124838.1714988803 157037.87663983586 130508.05431290345 153664.6190371695 143008.66813765632 0.9753100037782196 0.9286294008856157 0.916238898538486 0.9522553181749014 0.867528263206343 0.8729412917734078 1.0981004066737787 0.9125884186773902 1.0745126224744366 1.0 17.125743069693677 -7.246537047167921 24.996485508153732 1.0140160703736476 0.9183346101763997 0.45149598623661824 0.05510268417034705 774.9469023627368 1299862.3286962388 0.020370363346094236 0.01570865379717541 5.668432153216364e-08 7.246537047167921 -0.09568146019724788 DTCYS(ph)PKPSVYLSTPSSASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DTCYSPKPSVYLSTPSSASK 20 1 Q9Y5K6 Q9Y5K6 CD2AP CD2-associated protein 1 DT(0.195)CY(0.18)S(0.62)PKPS(0.004)VYLSTPSSASK;DT(0.105)CY(0.084)S(0.756)PKPS(0.027)VY(0.024)LS(0.003)TPSSASK 66.609 0.0027890000000000002 36856000.0 72918.0 66278.0 68805.0 84092.0 109320.0 120046.0 129786.0 151109.0 112395.0 101385.0 True False 85261.57720385247 72857.64182395767 70445.57214441565 79380.59786994234 87899.53076018646 113750.57643109476 117491.73051073075 147142.54886321997 114038.56424455036 119765.29793678183 0.7119055241599102 0.608336831111259 0.5881968596746645 0.6628013225654348 0.7339315500770872 0.949779096204796 0.9810164758471925 1.2285908472493363 0.9521836976913435 1.0 16.869850421403903 -6.793131370726914 1.648987114429976 1.0640642010585495 0.6327825932835378 0.8534944554155771 0.0762863541795481 0.1228206941206231 0.6916618485937831 0.032316552448209204 0.028694716006598522 1.6101585009928034e-07 6.793131370726914 -0.4312816077750117 DTCYS(ph)PKPSVYLSTPSSASK ddPTM_PC-9_Lapatinib_30min_R1 2 DTCYSPKPSVYLSTPSSASK 20 1 Q9Y5K6 Q9Y5K6 CD2AP CD2-associated protein 1 DT(0.172)CY(0.109)S(0.718)PKPS(0.001)VYLSTPSSASK;DT(0.155)CY(0.384)S(0.459)PKPS(0.001)VYLSTPSSASK 92.39 0.00029888 32148000.0 97318.0 88450.0 89372.0 82192.0 117056.0 123833.0 137505.0 127378.0 129849.0 137431.0 True False 95930.22747406461 88245.199459352 82024.17914589676 88236.67386447436 110170.99622095052 118536.95125882204 144624.33608286758 133296.44689625123 115224.03824941175 161185.76523470355 0.5951532217152057 0.5474751404434358 0.5088797948532295 0.5474222474670292 0.6835032613489775 0.7354058287108647 0.8972525326431848 0.8269740612774179 0.7148524442070511 1.0 17.298364815498168 -6.6746834278098435 1.5940045336401232 0.8447985881212382 0.5445616584910778 0.7821600186066864 0.07238383514230598 0.1737950586309338 0.9143152008448722 0.02994380242864319 0.02917608096060596 2.1150301963470614e-07 6.6746834278098435 -0.30023692963016035 DTDFEHR ddPTM_PC-9_AZD4547_30min_R2 2 DTDFEHR 7 0 P17858;P17858-2 P17858 PFKL ATP-dependent 6-phosphofructokinase, liver type 0 ; 116.9 0.0063712 7640200.0 58549.0 52177.0 73464.0 86367.0 83372.0 77971.0 66007.0 83600.0 64454.0 72804.0 False True 77166.36410514615 69042.19487315352 72489.81935947514 66456.42250684838 71797.2369054742 73095.4610441123 71881.49512749742 70681.54093688635 67860.90685455104 70255.15411981283 1.0983729958594493 0.9827349429112243 1.0318078476612738 0.9459294956995453 1.0219497459649938 1.0404284491278124 1.0231490632688818 1.0060691179517784 0.9659206887344002 1.0 16.100316449015835 -4.7535422362340345 24.99597590141855 1.0038531797168735 1.0983731674018722 0.507601485041185 0.02842322593880583 251.87516062606355 797170.0687390947 0.007129357035785476 0.07642124507464276 1.7638342188072175e-05 4.7535422362340345 0.0945199876849987 DTDFEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DTDFEHR 7 0 P17858;P17858-2 P17858 PFKL ATP-dependent 6-phosphofructokinase, liver type 0 ; 133.81 1.1973e-06 2668000.0 87146.0 98628.0 103861.0 102478.0 129596.0 108551.0 117558.0 97988.0 103817.0 84050.0 False True 101898.09658804274 108419.13603025586 106337.44013503571 96736.48989815846 104202.59411267027 102858.39446688593 106422.05519378393 95415.918826868 105335.12722253188 99287.59966056613 1.0262922755349217 1.0919705622948652 1.071004239185667 0.9743058572155119 1.0495026012201623 1.0359641568385907 1.0718564610042776 0.961005393957209 1.0609091929167427 1.0 16.59932592584969 -1.5228787452858106 0.10150511757450054 0.9832327111612866 1.2083897181821364 0.10259374858019199 0.03933073143018478 267.0358314729658 1.9240825173732157 0.47657175704597854 8.376862302096457 0.029999999999621937 1.5228787452858106 0.22515700702084973 DTDFEHR ddPTM_PC-9_Lapatinib_30min_R1 2 DTDFEHR 7 0 P17858;P17858-2 P17858 PFKL ATP-dependent 6-phosphofructokinase, liver type 0 ; 111.65 0.0077941 6213700.0 78384.0 82238.0 89831.0 71787.0 77564.0 77620.0 76013.0 73925.0 85763.0 69661.0 False True 77266.22978613479 82047.58296368751 82445.44193768768 77066.45545441187 73001.83801669121 74300.37354105749 79948.5812055346 77359.82537648082 76103.46781557266 81701.81103255221 0.9457101233086478 1.004232120766546 1.0091017677054819 0.9432649592517173 0.8935155426065806 0.9094091379621219 0.9785411142683351 0.946855698775864 0.9314783461195367 1.0 16.318080437586552 -5.829993097020216 7.957711921328909 0.9388689373890071 0.9880270585118343 0.25677084748687606 0.03296115234407524 0.29998679559779257 30.43533525843068 0.009478675036081744 0.014143440652621228 1.4791318983367047e-06 5.829993097020216 0.049158121122827136 DTDSEEEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DTDSEEEIR 9 0 P0DP25;P0DP24;P0DP23;E7EMB3;G3V361;A0A590UJI2;Q96HY3;A0A590UJC0;G3V226 P0DP25 CALM2;CALM1 0 95.35799999999999 0.025119 4304900.0 24400.0 25245.0 34709.0 30195.0 35090.0 19565.0 31098.0 25982.0 19184.0 19648.0 False True 28530.438078032796 27751.15676160729 35536.59419461552 28503.272043510828 28214.366395672667 18538.976957785937 28152.172309977203 25300.000030204566 19464.529707437665 23210.026866517564 1.2292289984028573 1.1956537974387567 1.5310880249725207 1.2280585544960838 1.2156111045426787 0.7987486212060352 1.2129314830991904 1.090046132893623 0.8386259016148276 1.0 14.502460572208976 -6.567829769942365 9.099318855258176 1.0071739084539357 1.2953178981014337 0.5251926745056337 0.13983278152219902 0.27639621921796287 52.44706364359056 0.04655129578564098 0.04660453340167565 2.705018440231993e-07 6.567829769942365 0.288143989647498 DTDSEEEIR ddPTM_PC-9_Lapatinib_30min_R1 2 DTDSEEEIR 9 0 P0DP25;P0DP24;P0DP23;E7EMB3;G3V361;A0A590UJI2;Q96HY3;A0A590UJC0;G3V226 P0DP25 CALM2;CALM1 0 ; 120.87 0.007607200000000001 11702800.0 18528.4 28735.0 30576.0 29418.0 32910.0 31890.0 35297.0 33591.0 29564.0 30784.0 False True 18264.181618307575 28668.465872973127 28062.15930677318 31581.49785557116 30974.29850354944 30526.139039220863 37124.5059504526 35151.76048997447 26234.190997278456 36104.97338289838 0.505863317627002 0.7940309377586287 0.7772380555213263 0.8747132291345262 0.8578956193946633 0.845482939856701 1.0282380091169694 0.9735988479256042 0.7266087892950682 1.0 15.139909958508035 -4.288616397256784 0.7899958654361273 0.9089807307287581 3.227691139260694e-21 0.6420220428816085 0.08690332562379563 3.3443856084294032 0.9278165023822152 0.032273928926193705 3.205678754593413 5.14497895591729e-05 4.288616397256784 -0.9089807307287581 DTDSEEEIREAFR ddPTM_PC-9_AZD4547_30min_R2 3 DTDSEEEIREAFR 13 1 P0DP25;P0DP24;P0DP23;E7EMB3;G3V361;A0A590UJI2;Q96HY3;A0A590UJC0;G3V226 P0DP25 CALM2;CALM1 0 ;; 127.83 0.0001456 164044900.0 87273.0 68507.9 110028.7 135716.0 143530.0 112586.0 89933.3 114699.0 98764.4 119952.0 False True 115023.99860883028 90651.73892999809 108569.64754652463 104428.77299129813 123603.33700814092 105545.97962206986 97937.18947611284 96974.90507081251 103984.88455248122 115752.51699054729 0.9937062415517367 0.7831513412136083 0.937946321766729 0.9021728054503222 1.067824184058432 0.9118244887123196 0.8460912299998685 0.8377779385888584 0.8983379995181698 1.0 16.820684039069626 -10.372048762090195 14.758806415282049 0.9999995056922508 0.9065672343131443 0.11326713462927429 0.0763656497130767 0.0 0.0 0.07580599873823131 0.018385655285480404 4.245718908212882e-11 10.372048762090195 -0.09343227137910648 DTDSEEEIREAFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DTDSEEEIREAFR 13 1 P0DP25;P0DP24;P0DP23;E7EMB3;G3V361;A0A590UJI2;Q96HY3;A0A590UJC0;G3V226 P0DP25 CALM2;CALM1 0 ;;; 158.08 8.805299999999999e-05 131756000.0 115280.0 85488.0 137282.0 169492.0 193215.0 164520.0 152678.0 169903.0 146614.0 108323.0 False True 134794.62711621405 93974.6836694902 140555.32352488438 159995.91274047818 155355.90775548277 155892.2815790924 138215.23454700317 165443.22627710892 148757.95238356275 127961.10241560353 1.0534031402637967 0.7344003911772408 1.098422261699311 1.2503480332705257 1.2140869750473384 1.2182786693472794 1.0801347592184332 1.2929181067834785 1.1625247796038312 1.0 16.96534580122055 -5.465053810270128 6.400602619088405 1.185249592435867 0.8959443775871645 0.5139889251042342 0.10706930647770435 0.1523705780355172 13.212043636894364 0.026028561426890383 0.054099117083476055 3.4272531931432237e-06 5.465053810270128 -0.28930521484870253 DTDSEEEIREAFR ddPTM_PC-9_Lapatinib_30min_R1 2 DTDSEEEIREAFR 13 1 P0DP25;P0DP24;P0DP23;E7EMB3;G3V361;A0A590UJI2;Q96HY3;A0A590UJC0;G3V226 P0DP25 CALM2;CALM1 0 ; 91.961 0.006292600000000001 126944000.0 39442.0 78168.0 130771.0 90657.0 111202.0 110178.0 83763.0 80777.0 123296.0 83450.0 False True 38879.549847223054 77987.00679862764 120019.51317065787 97324.2182028864 104661.31699154382 105465.94377746244 88099.83828449334 84530.19431093641 109409.10611556098 97874.22130986444 0.3972399404755673 0.7968084522657405 1.2262627642337265 0.9943805110312269 1.0693450797446633 1.077566108480833 0.9001332230840852 0.8636614746933049 1.117854166820676 1.0 16.578641303875315 -4.874142852704126 3.255951876377334 1.0235321437480067 0.367645967344329 0.7881020127675276 0.10065339922184532 0.124951266680932 2.2234186160205276 0.026340403955331076 0.1831615057573705 1.3361559418042463e-05 4.874142852704126 -0.6558861764036776 down DTEEPLPVKESDQTLAALLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 DTEEPLPVKESDQTLAALLSPK 22 1 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 DTEEPLPVKES(0.002)DQT(0.008)LAALLS(0.99)PK;DTEEPLPVKESDQTLAALLS(1)PK 95.052 8.0003e-05 78001000.0 86594.0 46008.0 69173.0 96343.0 90613.0 79402.0 66694.0 68385.0 66631.0 84268.0 True False 114129.09073290782 60879.18626452351 68255.7208231648 74132.60983451197 78032.94904423247 74436.98038789531 72629.63679660218 57817.669580968555 70152.97863011745 81317.8029691828 1.4034945186130963 0.7486575392057141 0.8393699575114176 0.9116405894857511 0.9596047383843462 0.9153835650983447 0.8931578835710404 0.7110087517106168 0.8627013528231141 1.0 16.311283616765017 -4.753619379370222 24.999892895863706 0.8673355771269222 1.4034954853600565 0.7835618848894353 0.08389158186929788 131.96817152230886 421857.32210640336 0.021547880117979694 0.227480871363942 1.763520939166379e-05 4.753619379370222 0.5361599082331343 DTEEPLPVKESDQTLAALLS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DTEEPLPVKESDQTLAALLSPK 22 1 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 DTEEPLPVKES(0.048)DQT(0.229)LAALLS(0.723)PK;DTEEPLPVKES(0.001)DQT(0.003)LAALLS(0.997)PK 58.272 0.004665399999999999 7889400.0 14994.9 8761.5 11336.099999999999 17893.0 14953.5 17909.9 18574.4 23502.0 15738.1 14902.0 True False 17533.240407225163 9631.28381726371 11606.39561639865 16890.513219888693 12023.469019597927 16970.673315422977 16814.898364989403 22885.097402427356 15968.239938939998 17603.614635832906 0.9960022853224421 0.5471196692558142 0.6593188874274343 0.9594911936726527 0.683011373989274 0.9640448093471923 0.9551957772787165 1.3000226303434164 0.9071000626448597 1.0 14.103584074421239 -7.035124641991507 2.0029213139680917 1.0733389741880415 0.7592664643003638 0.38440579116093965 0.16068487632101056 0.31707787670566434 2.539676569118446 0.07072833619248782 0.053486529826580094 9.223066882616892e-08 7.035124641991507 -0.31407250988767765 DTEEPLPVKESDQTLAALLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 DTEEPLPVKESDQTLAALLSPK 22 1 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 DTEEPLPVKESDQTLAALLS(1)PK;DTEEPLPVKESDQTLAALLS(1)PK 111.24 6.1547000000000006e-06 52077000.0 91699.0 50360.0 54421.0 63279.0 50502.0 55107.0 37761.0 38302.0 59360.0 43467.0 True False 90391.35544446313 50243.39451410915 49946.715451135016 67932.74875255594 47531.57165075215 52750.20207069122 39716.079814007964 40081.65074832551 52674.25171148861 50980.213033863205 1.7730674327394707 0.9855469705616055 0.9797274761868552 1.332531676700373 0.9323533351886873 1.034719137710396 0.7790489182072831 0.7862197578833496 1.033229336968446 1.0 15.637649781592495 -4.761439059849431 9.90499298995574 0.9821204331943297 1.7764967553271256 0.7264187594230072 0.14511514994524058 0.04121571367672828 82.82074027030586 0.038692102116716975 0.2191005948870732 1.7320520550395842e-05 4.761439059849431 0.7943763221327959 DTGKTPVEPEVAIHR ddPTM_PC-9_AZD4547_30min_R2 2 DTGKTPVEPEVAIHR 15 1 P60866;P60866-2;E5RIP1;E5RJX2 P60866 RPS20 40S ribosomal protein S20 0 ; 102.9 0.00062596 18105100.0 96403.0 74296.0 130385.0 201483.0 164756.0 142033.0 92579.0 119996.0 98670.0 142488.0 False True 127057.14869303298 98310.72906253349 128656.00970795432 155034.20723131904 141882.47329557073 133151.6540570004 100818.3516507129 101453.37543376359 103885.49476120248 137499.53848997154 0.9240550920270895 0.7149895202717624 0.9356832111646526 1.1275252916039888 1.031875996485027 0.9683789161715024 0.7332268366709175 0.7378452069580076 0.7555334068905207 1.0 17.069067250751587 -7.253984753242426 24.2064692485539 0.7848051282612039 0.9507999221456689 0.24535751326928368 0.12111803495487726 513.5993605573497 1667750.8149012954 0.05062626066753262 0.03838962382732479 5.5720531037126466e-08 7.253984753242426 0.16599479388446503 DTGKTPVEPEVAIHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DTGKTPVEPEVAIHR 15 1 P60866;P60866-2;E5RIP1;E5RJX2 P60866 RPS20 40S ribosomal protein S20 0 ; 88.075 0.002236 13453800.0 126983.0 74315.0 110458.0 173538.0 177135.0 199805.0 150632.0 186749.0 179271.0 129118.0 False True 148478.71387142755 81692.50206927485 113091.73763429798 163815.22847778728 142426.66832423737 189326.8740633999 136363.04647876037 181847.03662692165 181892.4992275886 152526.07130247433 0.9734644877660261 0.535596972843223 0.7414584055602261 1.0740146066761624 0.9337857266499126 1.2412754911122437 0.8940310683564315 1.1922357605756522 1.1925338250329527 1.0 17.21869633825341 -5.756759136692259 6.644652302950148 1.0775496277916383 0.7267053066426901 0.5111532110427038 0.14525987043966712 0.10315334255836645 20.952747500923362 0.038786310901317594 0.06324569472144098 1.750817437222859e-06 5.756759136692259 -0.35084432114894826 DTGKTPVEPEVAIHR ddPTM_PC-9_Lapatinib_30min_R1 2 DTGKTPVEPEVAIHR 15 1 P60866;P60866-2;E5RIP1;E5RJX2 P60866 RPS20 40S ribosomal protein S20 0 ; 107.99 0.00035185 17017400.0 305740.0 184173.0 231300.0 193950.0 186621.0 205376.0 144706.0 141673.0 198121.0 136032.0 False True 301380.09153415123 183746.55873405517 212283.40684382012 208213.72999823306 175644.31969100283 196592.54723483938 152198.16862810394 148255.64478271455 175806.52667338002 159544.94994875375 1.888998001070891 1.1516914749923144 1.33055547613388 1.3050474494185609 1.1009080497215376 1.2322078968841408 0.9539516523524586 0.9292405985293464 1.101924734877848 1.0 17.28360341837717 -1.5228787452803376 0.5188953297518086 1.0418319224981272 26.815193916566976 0.7331581188778022 0.13661761758257446 64.20458060962774 0.646581440260992 0.07329253274799158 1820.1867337110812 0.029999999999999995 1.5228787452803376 25.77336199406885 DTGS(ph)PPASEGPTDGSR ddPTM_PC-9_AZD4547_30min_R2 1 DTGSPPASEGPTDGSR 16 0 Q969R8 Q969R8 ITFG2 Integrin-alpha FG-GAP repeat-containing protein 2 1 DTGS(0.824)PPAS(0.176)EGPTDGSR 180.95 3.315e-06 6592800.0 5802.5 6464.5 6208.7 10570.0 11690.0 8681.0 8565.8 9348.9 7354.1 7542.3 True False 7647.574300502326 8554.02320481247 6126.368581307485 8133.249804872093 10067.04528408813 8138.175697681669 9328.139605846625 7904.242321349961 7742.822712307288 7278.246372697452 1.0507440815950277 1.17528629381121 0.8417369057866807 1.1174738238295938 1.3831690724090036 1.1181506204860046 1.2816465846551777 1.0860091726216878 1.0638308070131537 1.0 12.829375172699708 -4.73157736360476 22.865164909924687 1.1259404865094724 1.0507428128092042 0.01839930681083224 0.1396649986404378 6251.082642846326 4785653.725356345 0.036036755032356475 3.3437011307038094 1.855336277286301e-05 4.73157736360476 -0.0751976737002682 DTGS(ph)PPASEGPTDGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DTGSPPASEGPTDGSR 16 0 Q969R8 Q969R8 ITFG2 Integrin-alpha FG-GAP repeat-containing protein 2 1 DT(0.01)GS(0.99)PPAS(0.001)EGPTDGSR 177.39 8.5257e-06 6467900.0 11120.0 7716.6 9218.6 13500.0 12014.0 9884.1 9969.5 9096.1 10653.0 8402.0 True False 13002.396369988728 8482.653050767236 9438.406385735187 12743.638767590526 9659.942943220622 9365.760396036389 9025.116787070483 8857.337013114606 10808.779971504046 9925.216089804599 1.3100366029657609 0.8546567625344504 0.9509522311993314 1.2839658756327808 0.9732728089561222 0.9436328953741475 0.9093118684177851 0.8924074733459011 1.0890221304709993 1.0 13.276882797325316 -6.490596161808953 24.961946009597888 0.9567637132663108 1.0788551334174006 0.1737359495656191 0.13713746290672274 1254.0474365101024 969671.2090452407 0.04257987432880928 0.04823754097565239 3.2314976035587587e-07 6.490596161808953 0.12209142015108976 DTGS(ph)PPASEGPTDGSR ddPTM_PC-9_Lapatinib_30min_R1 1 DTGSPPASEGPTDGSR 16 0 Q969R8 Q969R8 ITFG2 Integrin-alpha FG-GAP repeat-containing protein 2 1 DT(0.06)GS(0.935)PPAS(0.005)EGPTDGSR 125.33 3.214e-05 7154300.0 8198.7 6945.0 8362.5 7283.4 7439.9 5567.5 5872.8 5723.8 7010.3 5955.0 True False 8081.785034542563 6928.91927919953 7674.967530183506 7819.045532710147 7002.299709406183 5329.391003476395 6176.864848168906 5989.748643759216 6220.726192268339 6984.313815461276 1.1571337210896508 0.9920687217491404 1.0988864093124395 1.1195152078363109 1.002575184108293 0.7630514814037487 0.8843910814109027 0.8576001597321734 0.8906710604121808 1.0 12.76990266748947 -6.555172714886914 6.3102071793288 0.8708139435806053 1.082743147160091 0.6932672562187743 0.06670957565865161 0.09569392445023123 11.43530699200133 0.021047666084993127 0.02131276840171639 2.785013374379566e-07 6.555172714886914 0.21192920357948575 DTGSPPAS(ph)EGPTDGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DTGSPPASEGPTDGSR 16 0 Q969R8 Q969R8 ITFG2 Integrin-alpha FG-GAP repeat-containing protein 2 1 DT(0.002)GS(0.082)PPAS(0.876)EGPT(0.038)DGS(0.002)R 77.372 0.010675 7703700.0 8883.9 10088.0 8040.7 11141.0 11245.0 8252.9 10914.0 7577.3 10550.0 6671.2 True False 10387.768804976877 11089.469970730614 8232.420782524558 10516.805889609344 9041.62297290793 7820.10339559988 9880.14690948265 7378.403903812984 10704.273791360889 7880.6357508098545 1.318138426066625 1.4071796135979262 1.0446391690770065 1.3345123695799015 1.147321518061378 0.992318848742152 1.2537246006411749 0.9362701356999962 1.3583007932146671 1.0 12.944096304894934 -5.025334427764807 0.6817110030019549 1.1130753868542038 1.4758944742795104 0.23487545191691273 0.1458981215256183 3.392222211402191 1.486390434688926 0.06366402869702878 0.9065391290495493 9.433341835621112e-06 5.025334427764807 0.36281908742530655 DTHDQLSEPSEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DTHDQLSEPSEVR 13 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 62.081 0.042693 4410800.0 20324.0 16722.0 31434.0 28720.0 30624.0 22356.0 24764.0 23660.0 24103.0 18170.0 False True 23764.451782702417 18382.049648152002 32183.505774108864 27110.911511496284 24623.44703622341 21183.612004511255 22418.17464416604 23038.950069842187 24455.460776603948 21464.077166359137 1.1071732364039708 0.856409968417481 1.4994125079158025 1.2630830247846614 1.1471933708296569 0.9869332764845135 1.0444508967430601 1.0733724954153334 1.1393669798640698 1.0 14.389636525960276 -6.5851820778452375 6.987456154161319 1.0537963344200392 1.1839597481857578 0.14700278102057285 0.1530165232286336 0.47865940532087253 43.53682621267698 0.05362599203825326 0.05368135293808763 2.5990696754482473e-07 6.5851820778452375 0.1301634137657186 DTHDQLSEPSEVR ddPTM_PC-9_Lapatinib_30min_R1 4 DTHDQLSEPSEVR 13 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ;;; 183.06 5.074e-05 32921900.0 103330.0 123724.0 139551.0 126255.0 112456.0 139570.0 116604.0 116539.0 144887.0 98393.0 False True 101856.49525159881 123437.52467958 128077.65546243828 135540.21387433357 105841.55917700261 133600.9164535608 122641.1845722461 121953.82738653627 128568.30033225157 115400.09894956865 0.882637850216328 1.0696483434864628 1.1098574145799467 1.1745242431166927 0.9171704369443977 1.1577192538798962 1.062747655232444 1.0567913589037015 1.1141090995809075 1.0 16.816284935456522 -4.762232034021966 6.058259066241403 1.0775351631213892 0.8757402896211361 0.39293021969986275 0.07113176196126615 0.12882697746692456 18.677612442841696 0.016826386298249188 0.10802275913769277 1.728892403098597e-05 4.762232034021966 -0.20179487350025305 DTHEDHDTSTENTDES(ph)NHDPQFEPIVSLPEQEIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DTHEDHDTSTENTDESNHDPQFEPIVSLPEQEIK 34 0 C9JJ34;P43487-2;P43487 C9JJ34 RANBP1 Ran-specific GTPase-activating protein 1 DT(0.072)HEDHDT(0.063)S(0.146)T(0.146)ENT(0.146)DES(0.425)NHDPQFEPIVSLPEQEIK 46.556999999999995 0.009366 1941100.0 4458.2 5545.7 7467.8 8241.7 9204.1 8586.2 7785.0 7369.2 7786.0 3656.2 True False 5212.885206536306 6096.240445745518 7645.860673789216 7779.944268951913 7400.6226771846905 8135.924556858758 7047.548441480886 7175.766308312811 7899.855520335155 4319.040117536724 1.2069545696902135 1.411480393755264 1.7702685008051917 1.8013132680483284 1.7134878296535674 1.8837344260416167 1.6317395184327 1.661426176426757 1.8290766710545572 1.0 12.076495001786435 -5.048940137577068 3.281102175789304 1.6980050204696033 1.2249965667393945 0.2674427080137366 0.23740340911945446 0.27056854522474033 5.611901169347842 0.056644280852268664 0.22938888916182038 8.934286239493338e-06 5.048940137577068 -0.47300845373020883 DTHIYDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DTHIYDAR 8 0 Q9H967;A0A0C4DFX7 Q9H967 WDR76 WD repeat-containing protein 76 0 63.534 0.042425 0.0 6169.7 5590.5 8302.0 5906.5 8855.3 7919.7 6993.6 9502.2 8410.9 6028.9 False True 7214.108352870456 6145.487893672631 8499.951165510327 5575.577954131368 7120.167533302941 7504.376990164959 6331.115578720711 9252.777318413118 8533.893500640512 7121.891845253858 1.0129483162087125 0.8629010419145977 1.1934962437227727 0.7828787736852563 0.999757885687064 1.0537055536958195 0.8889654204647697 1.2992021669887217 1.1982621592783151 1.0 12.79804481141885 -7.75663798018407 24.999990234583024 1.1865491286840408 0.9721807349074416 0.32911061046775203 0.1266412208837498 118.68085747651283 617958.8956760524 0.05838651218877534 0.032314322001953416 1.751305936448763e-08 7.75663798018407 -0.21436839377659922 DTHPGSPGS(ph)PGPALRPLPAR ddPTM_PC-9_AZD4547_30min_R2 1 DTHPGSPGSPGPALRPLPAR 20 1 Q8N0Y2-2;Q8N0Y2 Q8N0Y2-2 ZNF444 Zinc finger protein 444 1 DT(0.004)HPGS(0.076)PGS(0.92)PGPALRPLPAR 46.162 0.032785 12045000.0 32385.0 30551.0 42052.0 62096.0 51927.0 51124.0 38002.0 52799.0 44771.0 62397.0 True False 42682.75635015386 40426.01329263297 41494.36300371132 47780.72657363648 44717.83237526469 47927.20819816584 41384.10438037119 44640.12775031897 47137.50365819198 60212.50002216869 0.7088686956103661 0.6713890517375819 0.6891320404971419 0.7935350061207365 0.7426669272792317 0.7959677505587756 0.6873008821280403 0.7413764207412684 0.782852458224408 1.0 15.877775398892865 -14.522878745278595 0.22432928133045116 2.388210082147622 0.7024908281109635 0.8126522375146008 0.039181753625842815 68.67945366428782 0.6857295843466761 43.12970436457713 0.07674286441682036 3.0000000000120386e-15 14.522878745278595 -1.6857192540366586 DTHPGSPGS(ph)PGPALRPLPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DTHPGSPGSPGPALRPLPAR 20 1 Q8N0Y2-2;Q8N0Y2 Q8N0Y2-2 ZNF444 Zinc finger protein 444 1 DT(0.003)HPGS(0.336)PGS(0.661)PGPALRPLPAR 53.861000000000004 0.011334 6016600.0 16689.0 21698.0 21484.0 22886.0 33648.0 21383.0 25833.0 22742.0 19430.0 18646.0 True False 19514.118077224975 23852.03404291366 21996.260038523717 21603.771617413113 27054.915944189055 20261.637837379843 23385.91122527626 22145.04659714078 19714.126992051388 22026.372198345227 0.8859433546978295 1.0828852717155841 0.998632904249944 0.9808138817810469 1.2282965029630075 0.9198808435145773 1.0617232386109035 1.0053878322642922 0.8950237839680403 1.0 14.426944278471845 -8.022997932220871 18.42050036325456 0.9484087476875471 1.0268624693404058 0.09261269941903238 0.09201182267811264 61.87163784574151 49548.3466548594 0.05765843084709694 0.022441376731542912 9.484229789571029e-09 8.022997932220871 0.07845372165285869 DTIEEHR ddPTM_PC-9_AZD4547_30min_R2 1 DTIEEHR 7 0 P23381-2;P23381 P23381-2 WARS Tryptophan--tRNA ligase, cytoplasmic;T1-TrpRS;T2-TrpRS 0 83.265 0.017852 2875600.0 18733.0 13185.0 22352.0 28815.0 23880.0 23878.0 21833.0 25676.0 19119.0 25518.0 False True 24689.70432939422 17446.793403272084 22055.597875462656 22172.14693731215 20564.674198804492 22384.904885294676 23776.09470387462 21708.364175783416 20129.591307787916 24624.62258707471 1.0026429539006891 0.7085100834166604 0.8956725244203126 0.9004055537870519 0.8351264725412987 0.9090456028773555 0.9655414867700154 0.8815714474006997 0.8174578609929151 1.0 14.587813992608686 -6.795747385139318 18.071318432144178 0.9104989315507289 0.8628704273635867 0.07060997074948738 0.08194738836908594 28.176134448756727 14838.44096458417 0.0279827429143671 0.02468911161178493 1.6004887097214669e-07 6.795747385139318 -0.04762850418714226 DTIEEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DTIEEHR 7 0 P23381-2;P23381 P23381-2 WARS Tryptophan--tRNA ligase, cytoplasmic;T1-TrpRS;T2-TrpRS 0 ; 101.64 0.0093436 4320000.0 52734.0 56086.0 59844.0 67099.0 84850.0 64841.0 65312.0 62513.0 68258.0 46818.0 False True 61660.82465602389 61653.84742053903 61270.907919633806 63339.66056789311 68224.25160082165 61440.62381394318 59125.174542068016 60872.099987998525 69256.14411855074 55305.73278891595 1.1149083747134003 1.1147822171681872 1.1078581700288648 1.1452639242597156 1.2335837201761977 1.1109268554209764 1.0690605035056608 1.1006472009027997 1.2522416868225756 1.0 15.755141412224102 -9.69638779441264 12.721938154719508 0.9999999992638462 1.1361747220722804 0.356722096452209 0.05581968164970572 0.0 0.0 0.05532303066542946 0.013417805821344152 2.0119269383613725e-10 9.69638779441264 0.13617472280843423 DTIEEHR ddPTM_PC-9_Lapatinib_30min_R1 1 DTIEEHR 7 0 P23381-2;P23381 P23381-2 WARS Tryptophan--tRNA ligase, cytoplasmic;T1-TrpRS;T2-TrpRS 0 108.46 0.0081886 3254200.0 30252.0 34519.0 40452.0 32339.0 32165.0 32410.0 30058.0 31286.0 34534.0 27493.0 False True 29820.600932462643 34439.073376341024 37126.192709235635 34717.31793974153 30273.117938823085 31023.89985140007 31614.256165076447 32739.661775158245 30644.417260858263 32245.128417880238 0.924809495127544 1.0680395788792771 1.151373696767441 1.0766686207548313 0.9388431500876376 0.9621267265351319 0.980435114271278 1.015336684378152 0.9503580467636046 1.0 14.976793594713303 -6.252184222112863 24.47373641932003 0.9749598842475425 1.0630062519731607 0.32833354230560974 0.056107733059624465 593.3671111864975 1569059.9117481855 0.017412826893821346 0.02214375559953824 5.595202098993198e-07 6.252184222112863 0.08804636772561814 DTIIDVVGAPLT(ph)PNSR ddPTM_PC-9_AZD4547_30min_R2 7 DTIIDVVGAPLTPNSR 16 0 Q9NPF5 Q9NPF5 DMAP1 DNA methyltransferase 1-associated protein 1 1 DTIIDVVGAPLT(0.998)PNS(0.002)R;DTIIDVVGAPLT(0.999)PNS(0.001)R;DTIIDVVGAPLT(1)PNSR;DTIIDVVGAPLT(0.693)PNS(0.307)R;DTIIDVVGAPLT(0.998)PNS(0.002)R;DTIIDVVGAPLT(0.923)PNS(0.077)R;DTIIDVVGAPLT(0.952)PNS(0.048)R 189.52 5.640600000000001e-39 168912400.0 136159.09999999998 153994.9 193095.0 222045.0 202691.0 196794.0 167431.7 216598.0 174779.3 191252.0 True False 179454.8615147823 203770.7398905989 190534.43413396814 170855.95581105247 174550.85335133492 184488.44007021826 182332.7969418183 183127.75602688658 184017.77697898692 184556.32569257793 0.9723582263644904 1.1041113823973019 1.0323917829364904 0.9257659154726202 0.9457863484023329 0.999632168542016 0.9879520317582425 0.9922594380857421 0.9970819276360753 1.0 17.493701661431942 -5.569942998941956 12.988610958879226 0.9780295616259682 1.0457345417361605 0.3292150674878115 0.03765153722158893 1.103764081023839 303.26520826431477 0.010126857276260738 0.017545677141171404 2.691888090479273e-06 5.569942998941956 0.06770498011019233 DTIIDVVGAPLT(ph)PNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 DTIIDVVGAPLTPNSR 16 0 Q9NPF5 Q9NPF5 DMAP1 DNA methyltransferase 1-associated protein 1 1 DTIIDVVGAPLT(0.999)PNS(0.001)R;DT(0.012)IIDVVGAPLT(0.988)PNSR;DTIIDVVGAPLT(1)PNSR;DTIIDVVGAPLT(0.963)PNS(0.037)R;DTIIDVVGAPLT(1)PNSR;DTIIDVVGAPLT(1)PNSR 204.9 3.6957e-39 130545500.0 173626.0 191944.0 198858.0 202231.4 223963.9 184211.7 214604.0 181993.1 175167.0 152450.6 True False 203017.45253018543 210998.93180629608 203599.52889316442 190901.03030104513 180079.7815333083 174551.31416583582 194275.15552158823 177215.9739626284 177728.48599159333 180088.68698171404 1.1273192999113795 1.1716390148800442 1.1305514649781285 1.0600389924572495 0.9999505496510914 0.9692519674129199 1.0787749012869123 0.9840483426958555 0.9868942295616806 1.0 17.458348029650956 -5.88730767943214 2.3367735473337157 1.0046400411850887 1.1504537104986179 0.8195251375659128 0.029445380641999624 0.11807892685913504 1.3104396774761389 0.009111065710541906 0.015299820028976025 1.296260599314781e-06 5.88730767943214 0.14581366931352924 DTIIDVVGAPLT(ph)PNSR ddPTM_PC-9_Lapatinib_30min_R1 3 DTIIDVVGAPLTPNSR 16 0 Q9NPF5 Q9NPF5 DMAP1 DNA methyltransferase 1-associated protein 1 1 DTIIDVVGAPLT(1)PNSR;DTIIDVVGAPLT(0.999)PNS(0.001)R;DTIIDVVGAPLT(0.998)PNS(0.002)R 201.04 5.2546e-12 125309000.0 63178.0 69158.0 82583.0 69369.0 80809.0 80718.0 70140.0 75845.0 81444.0 60949.0 True False 62277.07013457375 68997.86890005473 75793.34451959872 74470.62766820034 76055.9734966067 77265.87930284828 73771.50600234425 79369.03558578523 72270.91907665892 71483.95344056233 0.8712034958496813 0.9652217816607649 1.0602847334488792 1.0417810443307585 1.0639586905310985 1.0808842486180275 1.0320009240071477 1.11030562476905 1.0110089831104674 1.0 16.12533180479862 -4.926988302299687 2.0373512121718593 1.055419939546142 0.8465729070889528 0.7643761002770736 0.031279171756464025 0.2166691097450449 1.2694239898014408 0.007829628434217676 0.07636722466512348 1.1830734213198923e-05 4.926988302299687 -0.20884703245718927 DTIIDVVGAPLT(ph)PNSRK ddPTM_PC-9_AZD4547_30min_R2 4 DTIIDVVGAPLTPNSRK 17 1 Q9NPF5 Q9NPF5 DMAP1 DNA methyltransferase 1-associated protein 1 1 DTIIDVVGAPLT(0.88)PNS(0.12)RK;DTIIDVVGAPLT(0.957)PNS(0.043)RK;DTIIDVVGAPLT(0.921)PNS(0.079)RK;DTIIDVVGAPLT(0.918)PNS(0.082)RK 98.443 0.0011505999999999999 25328100.0 137692.0 108945.0 158675.0 221165.0 188354.0 162284.0 122379.0 168200.0 140770.0 163410.0 True False 181475.19182848203 144159.34071440878 156570.86582359672 170178.82621518776 162204.29832670133 152136.35582566186 133270.49392046352 142208.5548514869 148210.81481234924 157689.06563813335 1.1508419502271219 0.9141999803919649 0.9929088309959125 1.0792049881614243 1.0286337715953595 0.9647869699144903 0.8451473371419053 0.901828888870638 0.9398927833871823 1.0 17.26672309971073 -6.945656812897406 4.131736347610836 0.9122389826020793 1.0262157829389524 0.3748742306677004 0.0672728808268113 0.22809626462228103 8.10853577311394 0.024585055853904032 0.021098630674866205 1.1332955594802881e-07 6.945656812897406 0.11397680033687319 DTIIDVVGAPLT(ph)PNSRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DTIIDVVGAPLTPNSRK 17 1 Q9NPF5 Q9NPF5 DMAP1 DNA methyltransferase 1-associated protein 1 1 DTIIDVVGAPLT(0.772)PNS(0.228)RK;DTIIDVVGAPLT(0.957)PNS(0.043)RK 72.383 0.010265 8599000.0 31419.0 19729.1 23683.0 41750.0 48449.0 49927.0 40280.0 47104.0 47066.0 40102.0 True False 36737.616146463624 21687.67466292044 24247.69253827767 39410.88285532626 38955.76624405658 47308.740228539704 36464.38679805397 45867.569910813436 47754.25120987601 47372.17515274265 0.775510434722706 0.4578146262651571 0.511855165191287 0.8319415928918884 0.8223343369488745 0.9986609243928865 0.769742716699865 0.9682386287503603 1.0080654108852174 1.0 15.531752296138999 -5.90054402940143 3.487447024702704 0.9170111943395739 0.5695237941310053 0.6717251620877277 0.1075162104365748 0.13711768524615087 3.2634109340776423 0.03130040655543554 0.048731813166247556 1.2573493760112185e-06 5.90054402940143 -0.3474874002085686 DTIIDVVGAPLT(ph)PNSRK ddPTM_PC-9_Lapatinib_30min_R1 3 DTIIDVVGAPLTPNSRK 17 1 Q9NPF5 Q9NPF5 DMAP1 DNA methyltransferase 1-associated protein 1 1 DTIIDVVGAPLT(0.724)PNS(0.276)RK;DTIIDVVGAPLT(0.901)PNS(0.099)RK;DTIIDVVGAPLT(0.957)PNS(0.043)RK 92.932 0.0016659000000000003 10990700.0 79238.0 61302.0 61457.0 64932.0 57237.0 63974.0 48007.0 50611.0 67735.0 48476.0 True False 78108.0515895304 61160.058985383665 56404.24269088043 69707.31588680223 53870.43219227163 61237.98115067783 50492.56755994493 52962.571824539256 60105.97101882883 56855.01200979023 1.373811187940308 1.075719744371035 0.992071599266707 1.2260540174505437 0.9475054227936024 1.0770902860794904 0.8880935167378082 0.931537430955415 1.0571798139534083 1.0 15.794999913943085 -1.5228787452805987 0.8912851883281753 1.0013334845376687 168.63109777216778 0.5869828061100824 0.08938037307116718 623.1748952998328 1.4322460044419034 0.03051124982067428 212371.25901845563 0.029999999999981958 1.5228787452805987 167.6297642876301 DTINRWSAGLT(ph)SSQVDLY(ph)IPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DTINRWSAGLTSSQVDLYIPK 21 1 P08185 P08185 SERPINA6 Corticosteroid-binding globulin 2 DT(0.105)INRWS(0.105)AGLT(0.293)S(0.293)S(0.293)QVDLY(0.912)IPK 45.257 0.038173 27687000.0 71694.0 51140.0 40023.0 137320.0 64810.0 117620.0 85479.0 56726.0 119150.0 87191.0 True False 83830.37817895443 56216.84122751424 40977.30010807275 129626.40559744697 52110.94574247778 111451.80014182375 77381.81030563195 55237.00260616517 120892.34334034604 102998.03809642381 0.8139026696845898 0.5458049713032945 0.3978454431307805 1.2585327642463873 0.505941149031334 1.0820769230330949 0.7512940220588408 0.5362917937762453 1.1737344280982331 1.0 16.652257331694656 -3.3543356464949543 0.10752876561403107 1.1323149006985194 8.24905651730885e-13 0.11672596124959578 0.27464664187988314 170.40987138557202 1.9768786398605285 3.2828978686292465 28.340535745636302 0.00044224644804206193 3.3543356464949543 -1.1323149006976945 DTKS(ph)Y(ph)S(ph)M ddPTM_PC-9_Lapatinib_30min_R1 1 DTKSYSM 7 1 Q8NGI2 Q8NGI2 OR52N4 Olfactory receptor 52N4 3 DTKS(1)Y(1)S(1)M 61.678999999999995 0.021763 0.0 8112.3 6210.4 8420.5 6773.1 9050.4 5845.8 6224.6 8123.2 8077.7 5396.5 True False 7996.6171143863785 6196.020200365837 7728.198994069975 7271.216368399253 8518.073265771012 5595.788761225376 6546.879330798288 8500.633527199567 7167.904364048032 6329.277834615746 1.2634327838559576 0.9789458390464227 1.2210238191477905 1.1488224341538473 1.3458207221026741 0.8841117276636505 1.0343801460243138 1.3430653147675646 1.1324995601940107 1.0 12.627825183390863 -6.738885649376528 24.999996196196488 1.0974757193179712 1.179051475270045 0.12870807955254981 0.14078271297908948 728.3548386038161 807354.0003777918 0.04816494885870616 0.0481299273112026 1.824376001009632e-07 6.738885649376528 0.08157575595207378 DTLENTIGHR ddPTM_PC-9_AZD4547_30min_R2 1 DTLENTIGHR 10 0 H3BS70;Q96DC0;P42126-2;P42126 H3BS70 ECI1;DCI Enoyl-CoA delta isomerase 1, mitochondrial 0 125.74 0.00031013 3259800.0 16876.0 20551.0 24640.0 28057.0 26212.0 29725.0 24660.0 27815.0 24849.0 25100.0 False True 22242.216957393743 27193.70885329122 24313.257500510004 21588.89212632888 22572.916252054587 27866.291050983484 26854.692227249958 23516.830875113585 26162.467409761073 24221.256639845415 0.9182932697556231 1.1227208091489334 1.0037983520852194 0.8913200684564756 0.9319465371966206 1.1504890710394344 1.108724151953057 0.9709170430252159 1.0801449238897973 1.0 14.563986095987262 -6.743326043911104 24.99284612535129 1.0631542084242078 0.9790042493029245 0.25280348846941536 0.07572768664700277 398.64962583593706 550057.1869319134 0.0264302095950434 0.026380178894229805 1.8058179103000858e-07 6.743326043911104 -0.08414995912128331 DTLENTIGHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DTLENTIGHR 10 0 H3BS70;Q96DC0;P42126-2;P42126 H3BS70 ECI1;DCI Enoyl-CoA delta isomerase 1, mitochondrial 0 140.78 0.00010381 1830700.0 11576.0 17164.0 11349.0 18195.0 14213.0 17679.0 18966.0 14296.0 13595.0 15917.0 False True 13535.588163578192 18867.92848707576 11619.603201322174 17175.593138985903 11428.064678874196 16751.88211789919 17169.40317805092 13920.745147864072 13793.801155786854 18802.62610109732 0.7198775368291909 1.0034730460323638 0.6179776770992672 0.9134677808640537 0.6077908807752793 0.8909331083768958 0.9131385736085511 0.740361749099061 0.7336103521721281 1.0 14.198646552007819 DTLRT(ph)PPRER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DTLRTPPRER 10 2 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 DT(0.045)LRT(0.955)PPRER 58.246 0.036702 18440000.0 6300.0 6852.8 6949.8 8829.6 8313.2 7838.5 8410.4 8285.0 7977.5 6215.1 True False 7366.465569328144 7533.10069542256 7115.509589263271 8334.906137949427 6684.288136805532 7427.435261109383 7613.706025976981 8067.527528683113 8094.155845552747 7341.84843129547 1.0033529891365969 1.0260496067055616 0.9691714090599578 1.1352599029994865 0.910436683535033 1.0116573953568817 1.0370284945576766 1.0988414708065006 1.1024683935247808 1.0 12.84192761570599 -7.538153552184441 4.20744917731088 1.075253859137535 1.0101658371336917 0.15806134729671883 0.05880642507918168 0.34114763268980053 14.308138248437656 0.02752705189021946 0.016021245790904005 2.8963193637819364e-08 7.538153552184441 -0.06508802200384323 DTLRT(ph)PPRER ddPTM_PC-9_Lapatinib_30min_R1 1 DTLRTPPRER 10 2 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 DT(0.014)LRT(0.986)PPRER 59.975 0.033151 14978000.0 6084.7 5662.8 9550.1 5673.7 8187.4 7437.7 6940.9 6215.8 7358.6 5750.3 True False 5997.931062202681 5649.6881345213915 8764.92764245208 6090.962824908362 7705.833229047724 7119.606909125526 7300.265839915466 6504.608759893518 6529.796978506738 6744.2316932068825 0.8893423795395534 0.8377067087140603 1.2996184059454154 0.9031366509907237 1.1425813316599744 1.0556587070246621 1.0824458844242626 0.9644699434696581 0.9682047230203948 1.0 12.719438384539181 DTLS(ph)NPQSPQPSPYNSPKPQHK ddPTM_PC-9_AZD4547_30min_R2 1 DTLSNPQSPQPSPYNSPKPQHK 22 1 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5;Q96PU5-3 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 DT(0.069)LS(0.807)NPQS(0.123)PQPSPYNSPKPQHK 84.125 9.8908e-05 11932000.0 34207.0 41435.0 41934.0 46997.0 42167.0 46472.0 41729.0 54005.0 56685.0 42313.0 True False 45084.11445019958 54828.05344441252 41377.92776081114 36162.5677464119 36312.83990540156 43566.09849356788 45442.800160215476 45659.76816144198 59681.253375278924 40831.63474907482 1.104146692319761 1.342783696546826 1.0133791609151455 0.8856507452773804 0.8893310328757863 1.06696924483424 1.112931197574575 1.1182449206855856 1.4616425166918208 1.0 15.31739970849314 -8.016528741678593 21.466557620359907 1.2505288565735317 1.0598164677416833 0.15164948940744882 0.15931009054271109 196.36052942095412 255013.35303289452 0.10590312729287223 0.04265800202427252 9.626563021163954e-09 8.016528741678593 -0.1907123888318485 DTLSNPQS(ph)PQPS(ph)PY(ph)NSPK ddPTM_PC-9_Lapatinib_30min_R1 1 DTLSNPQSPQPSPYNSPK 18 0 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5;Q96PU5-3 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 3 DT(0.004)LS(0.027)NPQS(0.967)PQPS(0.753)PY(0.724)NS(0.524)PK 40.493 0.045787 1134800.0 6356.5 9677.9 11520.0 6869.5 11122.0 11163.0 10437.0 9602.5 9946.2 9245.5 True False 6265.855144360667 9655.491417158406 10572.870068485969 7374.7059459802185 10467.825826693315 10685.584512223977 10977.376791366793 10048.667205649723 8825.954217870747 10843.572356145622 0.5778404882233739 0.8904345450036244 0.9750356913046067 0.6800992978850356 0.9653484555540084 0.9854302771510438 1.0123395160585926 0.9266934249721325 0.8139341840485452 1.0 13.404552502611457 -6.293938183066077 24.79964817097398 0.9517850639744717 0.802549999911406 0.3412140326712423 0.11397521641998445 786.9757343633607 600534.3013342327 0.03584321341685093 0.040645330332407345 5.082317784886736e-07 6.293938183066077 -0.14923506406306575 DTLSNPQS(ph)PQPSPYNSPKPQHK ddPTM_PC-9_AZD4547_30min_R2 2 DTLSNPQSPQPSPYNSPKPQHK 22 1 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5;Q96PU5-3 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 DTLS(0.023)NPQS(0.975)PQPS(0.001)PYNSPKPQHK;DT(0.024)LS(0.233)NPQS(0.711)PQPS(0.032)PY(0.001)NSPKPQHK 124.73 9.819400000000001e-07 20490000.0 73364.0 71023.0 98385.0 106972.0 88970.0 91108.0 78045.0 111511.0 90325.0 97997.0 True False 96692.22593400306 93979.79581953688 97080.350616383 82311.2581009251 76618.05123398802 85411.00235737601 84990.8538068016 94279.53721786027 95099.39509785788 94566.15485796532 1.022482367811518 0.9937994831310513 1.0265866341102048 0.8704092730063245 0.8102058431905723 0.9031878528386822 0.8987449466931859 0.9969691308636209 1.0056388064069377 1.0 16.52903631622916 -10.814264089164062 14.768948405315564 1.0000010880911172 0.9436444117050853 0.04542212767839393 0.0700850409433769 0.0 0.0 0.07612648158703715 0.01846338379352895 1.533684084647476e-11 10.814264089164062 -0.05635667638603192 DTLSNPQS(ph)PQPSPYNSPKPQHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DTLSNPQSPQPSPYNSPKPQHK 22 1 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5;Q96PU5-3 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 DT(0.013)LS(0.22)NPQS(0.767)PQPSPYNSPKPQHK 116.73 5.918199999999999e-07 11612000.0 33819.0 45363.0 40922.0 42657.0 47043.0 36456.0 37501.0 37253.0 36149.0 29066.0 True False 39543.88874430292 49866.33884637716 41897.73567754923 40267.06658585995 37825.26185100113 34544.18318287987 33948.63379627164 36275.14822281618 36677.61073781091 34335.4357136706 1.1516932266148172 1.4523287038563182 1.2202476772667752 1.172755369165963 1.1016391976625204 1.0060796510913694 0.9887346145648312 1.0564930215338226 1.0682145129501814 1.0 15.067410650954022 -6.055748559709053 1.4715360320270585 1.0267529038729002 1.302825776814554 0.6838470003511223 0.07457445970673109 0.21680842156284102 0.9466922275395792 0.02556429251163392 0.042561147009017974 8.795315854020793e-07 6.055748559709053 0.2760728729416537 DTLSNPQS(ph)PQPSPYNSPKPQHK ddPTM_PC-9_Lapatinib_30min_R1 2 DTLSNPQSPQPSPYNSPKPQHK 22 1 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5;Q96PU5-3 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 DTLS(0.002)NPQS(0.875)PQPS(0.103)PY(0.02)NS(0.001)PKPQHK;DTLS(0.007)NPQS(0.991)PQPS(0.001)PY(0.001)NSPKPQHK 164.97 2.3904e-25 7222200.0 24376.4 30678.0 32603.0 25280.0 33494.3 26525.1 24928.1 29567.0 31699.0 28168.6 True False 24028.78806591572 30606.96697585071 29922.507191219473 27139.175531607845 31524.23112632744 25390.68330602815 26218.755043869933 30940.79075964023 28128.72481473174 33037.50497769981 0.7273184849199436 0.9264309455726241 0.905713285897862 0.8214656509299562 0.9541952743588286 0.7685411874524654 0.7936057841404032 0.9365353340249254 0.8514179516194857 1.0 15.011817116784506 -9.237272570043027 0.9335090272648978 1.0007252304316356 0.8538381777905081 0.26835278510112925 0.07260154783600628 4.492976653940631 4.735435499428581 0.0786650220818605 0.02249278662178708 5.79065151964661e-10 9.237272570043027 -0.14688705264112756 DTLSNPQSPQPSPY(ph)NSPKPQHK ddPTM_PC-9_Lapatinib_30min_R1 2 DTLSNPQSPQPSPYNSPKPQHK 22 1 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5;Q96PU5-3 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 DTLSNPQSPQPS(0.406)PY(0.486)NS(0.108)PKPQHK;DTLSNPQSPQPS(0.002)PY(0.566)NS(0.432)PKPQHK 95.365 0.00020473 13902900.0 89719.0 64566.0 65464.0 76009.0 80101.0 66579.0 61944.0 55026.0 74496.0 59384.0 True False 88439.59060755029 64416.501393923216 60081.802618347756 81598.955418591 75389.6166646251 63731.571373229395 65151.1572256802 57582.70884228914 66105.47600234259 69648.44527579381 1.2697999252868792 0.9248806795162023 0.8626438448185875 1.1715833008974654 1.0824307185335924 0.9150465759984334 0.9354287373924105 0.8267623004974944 0.9491306767951276 1.0 16.087803528241928 -6.770186136931578 24.690307852468123 0.9150809567510584 1.049617957810235 0.25742476650056745 0.11468909328518223 247.7292789959044 699284.3081542425 0.04098511031915389 0.03669592944155169 1.697515947771694e-07 6.770186136931578 0.13453700105917654 DTLYEAVR ddPTM_PC-9_AZD4547_30min_R2 2 DTLYEAVR 8 0 P62906 P62906 RPL10A 60S ribosomal protein L10a 0 ; 95.90899999999999 0.028944 14735600.0 69846.0 66618.0 95065.0 101642.0 96335.0 82319.0 87452.0 88177.0 64991.0 73253.0 False True 92055.57511294895 88150.96571400679 93804.37598563243 78210.00725324597 82960.54811314211 77171.57991676725 95235.0585830279 74551.27075588328 68426.29157824392 70688.43476647776 1.3022720819474705 1.2470351904836658 1.3270116433546615 1.1064045697378369 1.173608503105293 1.0917143684353294 1.3472509173196572 1.054645940346063 0.9679983975355103 1.0 16.109186576622484 -6.662179996374177 0.22566493221940548 0.947587950509299 1.4032324331286405 0.4975424579004236 0.09297049878084344 4.207008221156873 0.46578919608582664 0.22877232032496708 0.597452491607304 2.176807392375536e-07 6.662179996374177 0.45564448261934154 DTLYEAVR ddPTM_PC-9_Lapatinib_30min_R1 3 DTLYEAVR 8 0 P62906 P62906 RPL10A 60S ribosomal protein L10a 0 ;; 101.6 0.020899 29811000.0 130001.0 145386.0 150740.0 121556.0 145963.0 137312.0 138262.0 138642.0 145722.0 129257.0 False True 128147.16190073645 145049.36764948932 138346.73907322707 130495.63373892911 137377.7433142991 131439.48584990573 145420.52983883832 145083.81345750444 129309.25383931167 151598.90022587398 0.845304033932992 0.9567969651057744 0.9125840548123904 0.8607953853523861 0.9061922158380691 0.8670213679259425 0.9592452822689992 0.9570241818465541 0.852969603649156 1.0 17.209899761953515 -7.26711126310257 24.954189185632977 0.9387284485779493 0.8946568494525273 0.22896095312096365 0.0453059824156341 828.8214818739223 3646490.3317431724 0.01815364444695999 0.012602368755318892 5.406158033469755e-08 7.26711126310257 -0.04407159912542202 DTMSDQALEALSAS(ph)LGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DTMSDQALEALSASLGTR 18 0 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;F8W7E0;E9PDE4;P20810-2;E9PCH5;P20810-3;H0Y7F0;H0Y9H6 P20810-6 CAST Calpastatin 1 DTMSDQALEALS(0.038)AS(0.609)LGT(0.353)R 67.396 0.011462 1781000.0 7512.1 8704.1 8797.1 10339.0 14435.0 13031.0 10955.0 13047.0 12320.0 11845.0 True False 8783.750159261892 9568.185524607099 9006.856227187534 9759.739349490255 11606.56537251453 12347.631420235553 9917.263092668354 12704.530074439186 12500.156692849878 13992.404735031598 0.6277512926188278 0.6838128045747593 0.6436960906825281 0.6975026476368014 0.8294903979911441 0.8824524200133973 0.7087604511495685 0.9079590188405522 0.893352996111833 1.0 13.772356304966392 -5.792309734635752 0.19361080370242037 1.0453790725984888 0.3849885584473598 0.7855268881310339 0.05726517927302384 4.698609891866183 0.2583861279886229 0.17118839669350133 0.7920032815409696 1.6132076223406112e-06 5.792309734635752 -0.660390514151129 DTMSDQALEALSASLGT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 DTMSDQALEALSASLGTR 18 0 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;F8W7E0;E9PDE4;P20810-2;E9PCH5;P20810-3;H0Y7F0;H0Y9H6 P20810-6 CAST Calpastatin 1 DTMSDQALEALS(0.031)AS(0.301)LGT(0.668)R 71.872 0.032831 3325800.0 13649.0 13474.0 19332.0 22626.0 20922.0 18407.0 17102.0 20726.0 16212.0 18066.0 True False 17989.098083163506 17829.207001569062 19075.645048695587 17409.925268215316 18017.341440007844 17256.00738016664 18624.04486903603 17523.27293609936 17068.93322254604 17433.514838862426 1.0318686879517025 1.0226972108816845 1.0941938688217112 0.998646883840399 1.0334887489150475 0.9898180338080712 1.0682897305091743 1.005148594420951 0.9790873143088926 1.0 14.089575845707598 -7.988648815857279 24.586225834057526 0.9904017469975461 1.0331890263969066 0.2899705506100879 0.028913503777248984 209.05151110091043 452797.4483771041 0.01544838216193885 0.007410057641125041 1.0264816359951029e-08 7.988648815857279 0.042787279399360445 DTNGENIAESLVAEGLATR ddPTM_PC-9_Lapatinib_30min_R1 2 DTNGENIAESLVAEGLATR 19 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 ; 144.73 0.00094576 4080100.0 5535.1 6572.5 6511.2 7383.1 7129.4 7563.9 9023.9 6124.2 7011.2 3845.9 False True 5456.168458986979 6557.281780063195 5975.874269958846 7926.077803299594 6710.062708939699 7240.409629312092 9491.113387718193 6408.752689491284 6221.524824790917 4510.658690660372 1.2096167839708978 1.4537304260330086 1.3248340607841387 1.7571885498033983 1.4876015165663818 1.6051778965905483 2.1041524173332364 1.4208019557678009 1.3792940790827315 1.0 12.139122410018686 -5.731976643601844 24.67824209222967 1.5783493245022235 1.3418271491598115 0.0935818677056871 0.2732453418418913 375.20390454196706 314270.7069761656 0.0729525286593695 0.12633122436911579 1.8536313092006889e-06 5.731976643601844 -0.23652217534241204 DTNGSQFFITTVK ddPTM_PC-9_Lapatinib_30min_R1 2 DTNGSQFFITTVK 13 0 P23284 P23284 PPIB Peptidyl-prolyl cis-trans isomerase B 0 ; 113.24 0.0016897000000000001 14441700.0 36732.0 34205.0 44593.0 41532.0 39606.0 37386.0 38784.0 33426.0 39157.0 38499.0 False True 36208.1949441762 34125.800424048924 40926.73567395791 44586.40182669053 37276.452948391976 35787.087931022594 40792.045748430566 34979.09398761237 34746.726318510075 45153.50085330706 0.8018911991300072 0.7557730802516399 0.9063911967074071 0.987440641015657 0.8255495641300167 0.7925650781162306 0.9034082624280714 0.7746706972124064 0.7695245254934693 1.0 15.462550227009851 -5.252763504513129 24.764735152712966 0.8629387194390783 0.7788321355875375 0.17270517382392603 0.078577173895712 1091.7377042608375 3116276.149834664 0.020658878896586033 0.05287346747634154 5.5877439304837174e-06 5.252763504513129 -0.0841065838515408 DTPDS(ph)LSPETYGNFDSQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DTPDSLSPETYGNFDSQSR 19 0 K7EMG7;K7EMR5;K7EJ48;K7ENU5;Q96ED9-2;Q96ED9 K7EMG7 HOOK2 Protein Hook homolog 2 1 DTPDS(0.658)LS(0.341)PETYGNFDSQSR 149.95 9.504899999999999e-05 3912700.0 7492.4 6009.3 6649.9 6394.4 8076.7 6765.0 8431.6 6777.5 5574.8 6617.5 True False 8760.715338354627 6605.863589919858 6808.458835886187 6036.142498924512 6494.128614076077 6410.231490898132 7632.897808502275 6599.597806354834 5656.320903514569 7817.200365898824 1.120697299326204 0.8450421225912013 0.8709587214352217 0.7721616712366915 0.8307486453085663 0.8200162706410405 0.9764234574054752 0.8442405845377112 0.7235737397993897 1.0 12.932436301221559 -4.760946165423606 24.842801899799046 0.8488763875732673 1.1206976314686126 0.5062533472064956 0.07897964801966942 8.829004691002782 444231.0614075672 0.019078856637256315 0.109373292156867 1.7340189311529343e-05 4.760946165423606 0.27182124389534523 DTPDSLS(ph)PETYGNFDSQSR ddPTM_PC-9_AZD4547_30min_R2 3 DTPDSLSPETYGNFDSQSR 19 0 K7EMG7;K7EMR5;K7EJ48;K7ENU5;Q96ED9-2;Q96ED9 K7EMG7 HOOK2 Protein Hook homolog 2 1 DTPDS(0.031)LS(0.965)PET(0.004)YGNFDSQSR;DTPDS(0.223)LS(0.775)PET(0.002)YGNFDSQSR;DTPDSLS(0.994)PET(0.006)YGNFDSQSR 155.63 1.7577e-05 11175100.0 35067.4 34386.5 37256.7 46859.0 37507.1 39613.7 30942.2 48167.7 35226.3 36753.1 True False 46218.1037527678 45501.26366034246 36762.65181490468 36056.381514333145 32299.886584672535 37136.64907674836 33695.99585701597 40724.48874863231 37088.29030208324 35466.385155773 1.303152366664148 1.2829405494948234 1.0365491620710232 1.0166353677142117 0.9107183165920972 1.0470942813494903 0.950082612282553 1.1482559773082324 1.04573077124118 1.0 15.114164673352256 -5.263378860394368 4.374624930199421 1.0176844034698942 1.2997988760143424 0.7744889797922947 0.059196328292174784 0.08739106974698498 4.390953001285157 0.01616386191685861 0.04097051359416143 5.452819722962731e-06 5.263378860394368 0.2821144725444482 DTPDSLS(ph)PETYGNFDSQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DTPDSLSPETYGNFDSQSR 19 0 K7EMG7;K7EMR5;K7EJ48;K7ENU5;Q96ED9-2;Q96ED9 K7EMG7 HOOK2 Protein Hook homolog 2 1 DTPDSLS(0.998)PET(0.002)YGNFDSQSR;DTPDS(0.003)LS(0.817)PET(0.18)YGNFDSQSR;DTPDS(0.007)LS(0.993)PETYGNFDSQSR 237.81 1.0263e-43 12077200.0 45431.4 49617.8 48476.4 48618.4 59918.4 53846.5 57867.8 45073.6 45131.5 37339.7 True False 53122.038708948356 54543.52727138361 49632.261223770765 45894.4686709795 48177.819647833385 51022.69474865425 52386.14305740883 43890.465759426814 45791.46280709046 44109.092029097446 1.2043330811231694 1.236559737738489 1.1252161162381182 1.0404763861542263 1.092242379780838 1.1567387221436367 1.1876495445168371 0.9950435100879789 1.038141133734587 1.0 15.428788442890474 -1.522878745280349 0.1476494670996273 0.9796325012805663 1.8368033902541714 0.508107113651548 0.05823046833013584 66.74927430361089 0.6508994223094988 0.2418646298619419 12.20630061130755 0.029999999999999215 1.522878745280349 0.857170888973605 DTPDSLS(ph)PETYGNFDSQSR ddPTM_PC-9_Lapatinib_30min_R1 4 DTPDSLSPETYGNFDSQSR 19 0 K7EMG7;K7EMR5;K7EJ48;K7ENU5;Q96ED9-2;Q96ED9 K7EMG7 HOOK2 Protein Hook homolog 2 1 DTPDS(0.241)LS(0.759)PETYGNFDSQSR;DTPDS(0.007)LS(0.992)PETYGNFDSQSR;DTPDS(0.002)LS(0.569)PET(0.427)Y(0.001)GNFDSQSR;DTPDS(0.003)LS(0.961)PET(0.036)YGNFDSQSR 227.09 2.8901999999999996e-35 11571800.0 36093.9 35782.9 41025.2 37237.2 40475.2 39482.8 35556.600000000006 36290.7 41830.9 33371.0 True False 35579.19436718938 35700.04689354482 37652.26641785161 39975.747907657715 38094.528313304916 37794.212682902165 37397.546768220025 37976.89840771383 37119.46354309481 39139.13288593756 0.9090440115491869 0.9121317786366091 0.962010745807295 1.021375410236049 0.9733104824862392 0.9656374553070742 0.9555026902922709 0.9703050529604014 0.9483976983156824 1.0 15.256324173454503 -5.302582305187064 4.23780683390004 0.974741407587416 0.9095522875785981 0.6238321915705367 0.02006001315698993 0.13360545229496507 5.383572512750489 0.005551952906663035 0.01316076914523185 4.9821602776359804e-06 5.302582305187064 -0.06518912000881794 DTPGCATT(ph)PPHSQASSVR ddPTM_PC-9_Lapatinib_30min_R1 1 DTPGCATTPPHSQASSVR 18 0 Q15572-5;Q15572-4;Q15572-2;Q15572-6;Q15572 Q15572-5 TAF1C TATA box-binding protein-associated factor RNA polymerase I subunit C 1 DT(0.001)PGCAT(0.067)T(0.931)PPHSQASSVR 71.309 0.019190000000000002 2675300.0 10762.0 8669.4 15836.0 10323.0 12149.0 18159.0 9667.2 12314.0 16006.0 9873.9 True False 10608.531906490907 8649.326536946352 14534.025208727775 11082.187856518507 11434.419705852994 17382.38190069651 10167.720314027118 12886.153394467136 14203.235729347809 11580.590458855266 0.9160613998208477 0.7468813069313335 1.2550331747215984 0.9569622460868868 0.9873779533503405 1.5009927138391135 0.8779967092482943 1.1127371648492717 1.226469045754666 1.0 13.499421193355468 -5.254382601760889 24.987836667564007 1.1138847799465035 0.831471339061213 0.2954809083859071 0.1749298511075274 662.932604660227 2347408.9442765513 0.04356738741899695 0.11016936053498047 5.566950994254349e-06 5.254382601760889 -0.2824134408852905 DTPGHGSGWAET(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 DTPGHGSGWAETPR 14 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 DT(0.007)PGHGS(0.012)GWAET(0.98)PR;DTPGHGSGWAET(1)PR 85.046 0.014780000000000001 16149000.0 53637.0 33984.0 82858.0 135161.0 96654.0 89986.0 57309.0 107090.0 49724.0 63224.0 True False 70692.45028109312 44968.66340665895 81759.24878154448 104001.71966663358 83235.26046948285 84359.16119474532 62409.38997775621 90541.70118338727 52352.309126442036 61010.54700388788 1.1586922876890164 0.7370637638078107 1.3400838510157005 1.704651486897931 1.364276580968512 1.3826979979276297 1.0229278877597867 1.4840335913988367 0.858086211275993 1.0 15.89677104509237 -8.276879797156582 24.828110235518032 0.9290430437328632 1.2711661341418505 0.23268652378849664 0.25073659948512217 1375.4412684789772 2211678.3443423514 0.25517079988345504 0.06685304106218831 5.28591533654976e-09 8.276879797156582 0.34212309040898736 DTPGHGSGWAET(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DTPGHGSGWAETPR 14 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 DTPGHGS(0.003)GWAET(0.997)PR 81.639 0.021356 6911600.0 19502.0 29979.0 50207.0 42000.0 49762.0 55766.0 48217.0 35950.0 51474.0 34242.0 True False 22803.303417942454 32955.11699569121 51404.12529110785 39646.87616583719 40011.49331950591 52841.532789567675 43649.53669915013 35006.35059217356 52226.70987075932 40449.80354047715 0.5637432427854373 0.8147163672306545 1.2708127306395685 0.9801500303002338 0.9891640951844765 1.306348317283925 1.0791037997371502 0.8654269620158611 1.2911486657406703 1.0 15.303845075236405 -5.00469427189173 3.9137354485294003 1.0912590783983196 0.5912637745432444 0.5911401422481818 0.1428224060331046 0.13889090482702823 4.790957780888766 0.035808957329087336 0.14456537770737385 9.892492464254918e-06 5.00469427189173 -0.4999953038550752 DTPGHGSGWAET(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 DTPGHGSGWAETPR 14 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 DTPGHGS(0.081)GWAET(0.918)PR 78.848 0.028243 5841600.0 13313.0 10033.0 25225.0 12967.0 15555.0 27454.0 14752.0 14972.0 26357.0 15191.0 True False 13123.154178694811 10009.769204925688 23151.097871315847 13920.63643664394 14640.085482306637 26279.856418399806 15515.786377909646 15667.653777973206 23388.397108485602 17816.744109264855 0.7365629824514717 0.5618180933361738 1.299401154853938 0.7813232513905328 0.8217037519607003 1.4750089161764446 0.8708541966341262 0.879378054816755 1.3127200438560176 1.0 14.120946097633341 -5.245152848359951 24.9420532269285 1.0410513011649463 0.6491904876045416 0.3365333236648922 0.22726597599419698 924.5579771523605 1415911.3791846833 0.056916064524842484 0.14957882137819092 5.686527603549392e-06 5.245152848359951 -0.3918608135604047 DTPRPDHPPHDGHS(ph)PASR ddPTM_PC-9_AZD4547_30min_R2 2 DTPRPDHPPHDGHSPASR 18 1 Q9C0J8 Q9C0J8 WDR33 pre-mRNA 3 end processing protein WDR33 1 DTPRPDHPPHDGHS(0.783)PAS(0.217)R;DTPRPDHPPHDGHS(0.768)PAS(0.232)R 94.671 0.00039762 6661500.0 9466.0 7356.8 15259.3 22871.9 18981.8 16714.0 11870.3 19478.1 10036.1 12898.7 True False 12475.991094968542 9734.741729934936 15056.951711750495 17599.136822332446 16346.50471971805 15668.870937801104 12926.733704181881 16468.207207210136 10566.587756895771 12447.12043905872 1.0023194646545899 0.7820878553876273 1.2096734972132346 1.4139123107628042 1.3132760142999154 1.2588350064190446 1.038532065908043 1.3230535759526643 0.8489182545175759 1.0 13.603524402261169 -5.273464115909938 24.251627294196396 1.198793273930428 0.8922036660509528 0.29993117100285527 0.17041492357041396 484.1157947707927 976371.9759424878 0.043998685290939206 0.09281459286712714 5.327652428563757e-06 5.273464115909938 -0.3065896078794751 DTPRPDHPPHDGHS(ph)PASR ddPTM_PC-9_Lapatinib_30min_R1 1 DTPRPDHPPHDGHSPASR 18 1 Q9C0J8 Q9C0J8 WDR33 pre-mRNA 3 end processing protein WDR33 1 DTPRPDHPPHDGHS(0.84)PAS(0.16)R 87.208 0.00070186 2201600.0 5253.6 3552.0 3692.4 4052.1 3764.5 4254.4 3978.9 4712.5 4771.7 3714.7 True False 5178.682700607756 3543.775562234228 3388.8251250761828 4350.104951409337 3543.0795112917617 4072.4492294907855 4184.907973092778 4931.459953827056 4234.260897771397 4356.780945473382 1.1886488591969064 0.8133931006827753 0.7778277511512511 0.998467677363724 0.8132333380159859 0.9347381198317963 0.960550467298757 1.131904499112069 0.9718783089543941 1.0 12.089046862495405 -7.547487318281098 7.403064993335182 1.0408791473690377 0.911354397130922 0.15496302509550464 0.11696744900531973 0.297876488221315 64.24182472506845 0.05364312192217715 0.031277885524132895 2.8347364086731577e-08 7.547487318281098 -0.12952475023811572 DTPTS(ph)AGPNSFNK ddPTM_PC-9_Lapatinib_30min_R1 1 DTPTSAGPNSFNK 13 0 Q8WW12;Q8WW12-3 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 1 DTPT(0.052)S(0.611)AGPNS(0.338)FNK 136.83 5.7013000000000005e-05 6141700.0 23543.0 30329.0 31346.0 32194.0 29296.0 24464.0 24758.0 33107.0 21330.0 29893.0 True False 23207.272502742577 30258.7750639082 28768.852879059148 34561.65415603572 27572.866878152065 23417.731748369373 26039.84809817562 34645.2720830456 18927.59078514238 35059.96522008124 0.6619308478221245 0.8630577604388759 0.8205613638938026 0.9857868922311394 0.7864487801134268 0.6679336845136525 0.7427231583008193 0.9881718896629675 0.5398633645620747 1.0 15.097536944476301 -6.490684128736646 24.830416462412625 0.7778529299068228 0.8406165770598955 0.018939534823878112 0.14746104186704814 2384.6729590903997 1839204.0034646785 0.04413515532993959 0.05000167077622312 3.230843125685561e-07 6.490684128736646 0.0627636471530727 DTPTSAGPNS(ph)FNK ddPTM_PC-9_AZD4547_30min_R2 2 DTPTSAGPNSFNK 13 0 Q8WW12;Q8WW12-3 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 1 DTPTS(0.001)AGPNS(0.999)FNK;DTPTSAGPNS(1)FNK 167.92 0.0001028 12649500.0 48069.0 56775.0 61791.0 67073.0 69209.0 58950.0 60345.0 63963.0 53714.0 62542.0 True False 63353.942102687804 75126.40845436271 60971.610966477805 51610.356117519965 59600.52498429905 55263.84718100849 65715.58809624494 54078.988073517474 56553.21238069561 60352.42361630322 1.0497331889348314 1.2447952203541424 1.0102595275064865 0.8551496862104188 0.9875415337620169 0.9156856323178356 1.0888641111422235 0.8960532955118794 0.9370495663975072 1.0 15.88112408705028 -5.464246268510388 6.864512373357073 0.9536351369992754 1.1444179221803557 0.5114583260877543 0.074428802289854 0.17901267833325465 17.440861791949473 0.018634722330975437 0.038724239053237935 3.433631871474377e-06 5.464246268510388 0.19078278518108027 DTPTSAGPNS(ph)FNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DTPTSAGPNSFNK 13 0 Q8WW12;Q8WW12-3 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 1 DTPTS(0.002)AGPNS(0.998)FNK;DTPTSAGPNS(1)FNK 150.34 0.00012706 9298700.0 35157.0 32528.0 37979.0 31704.0 40279.0 34076.0 28997.0 38423.0 30875.0 24743.0 True False 41108.38571759836 35757.164869937085 38884.56339615955 29927.72766575484 32386.61909522085 32288.99457263041 26250.194239899978 37414.43696253366 31326.48846523864 29228.710034519765 1.4064385896280893 1.223357610640602 1.3303550977869365 1.0239154458205484 1.1080413421246276 1.1047013205336937 0.8980962282939585 1.2800577554858346 1.0717711602134117 1.0 14.835098538906639 -5.756457540095558 24.999999584235017 1.0771102598243496 1.3103812085892879 0.5650111318173492 0.10047637104429816 94.64847481660205 474960.08233871154 0.026902804278038987 0.04479976532747531 1.7520337178673187e-06 5.756457540095558 0.23327094876493826 DTPTSAGPNS(ph)FNK ddPTM_PC-9_Lapatinib_30min_R1 1 DTPTSAGPNSFNK 13 0 Q8WW12;Q8WW12-3 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 1 DTPT(0.004)S(0.046)AGPNS(0.951)FNK 150.01 0.00012513 6444900.0 19800.0 29028.0 30801.0 27472.0 26469.0 21719.0 28538.0 30849.0 25395.0 32735.0 True False 19517.648369124694 28960.787449474992 28268.660675298313 29492.38252390549 24912.14546005623 20790.128999461824 30015.55800249358 32282.357159811327 22534.74767879468 38393.20113335429 0.5083621003972143 0.7543207285290717 0.736293401977877 0.7681668017591747 0.6488686726987627 0.5415054849750545 0.7817935758531322 0.8408352574634852 0.5869463085540294 1.0 15.228563233213874 -14.522878745273506 0.29047771079048246 3.389062144853402 0.6761191547728163 0.44129850868938236 0.10567783616253716 244.50427568738272 2.3001607900050924 354.10638670315353 0.11372239878787158 3.000000000047194e-15 14.522878745273506 -2.712942990080586 DTQS(ph)PSTCSEGLLGWSQK ddPTM_PC-9_AZD4547_30min_R2 3 DTQSPSTCSEGLLGWSQK 18 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 DT(0.094)QS(0.776)PS(0.125)T(0.005)CSEGLLGWSQK;DT(0.269)QS(0.706)PS(0.02)T(0.005)CSEGLLGWSQK;DT(0.026)QS(0.974)PS(0.001)TCSEGLLGWSQK 270.49 1.1671999999999998e-78 33514700.0 58316.0 63830.0 68634.0 66529.0 71862.0 81894.0 77050.0 92244.0 78244.0 67239.0 True False 76859.27495184718 84461.79923631829 67723.86831534111 51191.766912803694 61885.20172841246 76773.15523395257 83907.3007343717 77989.80935624569 82379.81810170811 64884.98307595872 1.1845464282832678 1.3017156702875552 1.0437525773268523 0.7889617055594385 0.9537677101027442 1.1832191609586575 1.2931698022660216 1.2019700963001807 1.2696284131764164 1.0 15.985597000320913 -6.91104671545094 7.662517844849075 1.2122085259793014 1.0533652010514274 0.17012399957554092 0.14623047616383708 0.4245468631251598 31.60613511099159 0.0572215844554282 0.05045583382339953 1.227307207161468e-07 6.91104671545094 -0.158843324927874 DTQS(ph)PSTCSEGLLGWSQK ddPTM_PC-9_Lapatinib_30min_R1 3 DTQSPSTCSEGLLGWSQK 18 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 DT(0.001)QS(0.369)PS(0.369)T(0.262)CSEGLLGWSQK;DT(0.219)QS(0.71)PS(0.068)T(0.003)CSEGLLGWSQK;DT(0.001)QS(0.999)PSTCSEGLLGWSQK 270.49 1.1671999999999998e-78 28448400.0 44667.0 76821.0 78633.0 69744.0 96601.0 103990.0 99441.0 101984.0 92410.0 86011.0 True False 44030.04038907539 76643.12569436818 72168.09827215775 74873.20641916347 90919.11910487323 99542.59011252997 104589.56841145013 106722.54895089622 82001.81267955975 100877.88674754674 0.4364687029900154 0.7597614121930649 0.7154005758741057 0.7422162461287317 0.9012789823046555 0.9867632374342017 1.0367938086688127 1.0579379920792364 0.812881943936578 1.0 16.622250433062845 -4.489935025707526 0.4616406634620658 1.0030582441402836 4.739227567097976e-16 0.7706774450049633 0.08725175462963287 3.090917340895851 0.4180285049992225 0.061373131716396946 1.7916164054005443 3.236420730220396e-05 4.489935025707526 -1.003058244140283 down DTQSPS(ph)TCSEGLLGWSQK ddPTM_PC-9_AZD4547_30min_R2 1 DTQSPSTCSEGLLGWSQK 18 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 DT(0.001)QS(0.081)PS(0.723)T(0.194)CSEGLLGWSQK 229.48 3.0574e-35 16965000.0 16299.0 15268.0 15040.0 14008.0 15940.0 20489.0 17692.0 20605.0 12995.0 15746.0 True False 21481.74295973931 20203.08241798698 14840.55977303857 10778.672021442595 13727.00614442812 19207.819591037878 19266.553726054608 17420.970705795982 13681.889170181703 15194.737332709394 1.4137620473041024 1.3296105076128053 0.976690774449362 0.7093687627123091 0.9034052938103958 1.2641100119374624 1.2679754380867052 1.1465134489883035 0.9004360437826711 1.0 13.891284115148522 -5.185345011495855 4.856032650364167 1.0286553980374527 1.3880338879435037 0.4264107239973729 0.1631353308067773 0.23978604732713601 10.325899267465257 0.04818053024603585 0.13581928323477233 6.5261189980728895e-06 5.185345011495855 0.35937848990605104 DTQSPS(ph)TCSEGLLGWSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DTQSPSTCSEGLLGWSQK 18 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 DTQS(0.009)PS(0.443)T(0.443)CS(0.104)EGLLGWSQK;DT(0.001)QS(0.132)PS(0.423)T(0.423)CS(0.02)EGLLGWS(0.001)QK 147.6 5.7723e-05 16014000.0 52757.0 66370.0 62623.0 58989.0 71373.0 55168.0 67991.0 47619.0 51684.0 45076.0 True False 61687.71810175314 72958.77497595058 64116.16981905002 55684.037574918366 57387.97300536746 52274.89296228651 61550.400267787656 46369.05170650108 52439.780723478325 53247.92197858034 1.1585000091941204 1.3701713093198111 1.2041065160221947 1.0457504350558127 1.0777504712475448 0.981726441518502 1.1559211698917957 0.8708142962865973 0.984823046138268 1.0 15.700437604236388 -5.727286787445596 2.844324526823191 1.0140933405715291 1.270369404185986 0.6155467421408971 0.08349553043797191 0.16435119177007862 2.7067616829352703 0.023902378517820042 0.04351752431312738 1.8737567594821537e-06 5.727286787445596 0.256276063614457 DTQSPST(ph)CSEGLLGWSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DTQSPSTCSEGLLGWSQK 18 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 DT(0.004)QS(0.042)PS(0.322)T(0.631)CSEGLLGWSQK 110.92 0.0005233 10294000.0 14250.0 26015.0 23186.0 17820.0 28775.0 17075.0 27998.0 17484.0 20095.0 15696.0 True False 16662.243549670795 28597.597272854568 23738.842173394656 16821.603173219497 23136.74531306586 16179.556941180424 25345.82675203363 17025.06352582928 20388.851358994987 18541.56055053237 0.8986429974036023 1.542351151884757 1.2803044333133577 0.9072377229184472 1.2478316078093845 0.8726103122272453 1.366973760539584 0.918210928332052 1.0996297373906632 1.0 14.178475053058037 -5.727406919701729 24.809884570945776 1.0684628373795204 1.2706249957328533 0.1337689289059495 0.20643819774623734 297.0555600013578 216553.1000282382 0.052345224308787915 0.0906580179910825 1.87323852241857e-06 5.727406919701729 0.20216215835333284 DTQSPSTCS(ph)EGLLGWSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DTQSPSTCSEGLLGWSQK 18 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 DTQS(0.002)PS(0.331)T(0.331)CS(0.336)EGLLGWSQK 87.15700000000001 0.0016707 10261000.0 23041.0 28620.0 29104.0 21875.0 29900.0 23511.0 27096.0 19611.0 21987.0 22091.0 True False 26941.386219506297 31461.20445700935 29797.94973753463 20649.414669706875 24041.309638945935 22278.04177124996 24529.270721948116 19096.23202957207 22308.518279682652 26095.92342774023 1.0323982707148556 1.2055984354845928 1.1418622460341492 0.7912889048316389 0.9212668678123795 0.8536981583709039 0.939965615314201 0.7317706952371184 0.8548660230957175 1.0 14.671536833473782 -5.7529502301680395 24.999899952311626 0.8635529198748385 1.1345176242948423 0.675138122689855 0.08129184909905972 98.05685280259361 288766.9391002398 0.021304706048810386 0.036150631297015505 1.7662402189339003e-06 5.7529502301680395 0.27096470442000375 DTS(ph)GLER ddPTM_PC-9_AZD4547_30min_R2 1 DTSGLER 7 0 Q9H307 Q9H307 PNN Pinin 1 DT(0.224)S(0.776)GLER 85.86200000000001 0.019 41655000.0 225920.0 153310.0 265860.0 323930.0 270770.0 288240.0 277720.0 294460.0 250830.0 260280.0 True False 297757.8605720787 202864.45935954835 262334.5226901621 249252.94316861106 233178.25933041426 270216.30723416223 302436.5419850711 248957.97301765028 264088.36172040616 251167.67642306563 1.1854943470932016 0.8076853767514433 1.0444597267694873 0.9923766732976046 0.92837686222669 1.075840295544285 1.2041220681424325 0.9912022779488021 1.0514424685586412 1.0 17.938291285542554 -6.7860572407388515 24.422145152503226 1.0726966655373809 0.9844278209680525 0.1048662114610397 0.10398786977407405 346.13551018436937 343380.66261173185 0.035160340772003806 0.031023658345339506 1.6366008004900435e-07 6.7860572407388515 -0.08826884456932838 DTS(ph)GLER ddPTM_PC-9_Lapatinib_30min_R1 1 DTSGLER 7 0 Q9H307 Q9H307 PNN Pinin 1 DT(0.224)S(0.776)GLER 85.86200000000001 0.019 37959000.0 251160.0 242730.0 235700.0 180700.0 223710.0 216400.0 237500.0 211310.0 258270.0 172370.0 True False 247578.4123428967 242167.97359828636 216321.6558283115 193989.28079752918 210551.81763078237 207145.07645303855 249796.5879035751 221128.23402508127 229180.9128963303 202163.924831412 1.224641896665573 1.1978792645633212 1.0700309464643896 0.9595642791328878 1.0414905518200894 1.0246391715326086 1.2356140597877925 1.0938065938791204 1.1336390163944838 1.0 17.62516605273523 -5.228446115719634 4.997468991779913 1.0723350933665412 1.2152391900345465 0.38058037744184003 0.07228926437592366 0.2189711025540861 14.58774125481979 0.020123717350332544 0.05374853275099585 5.909542825802123e-06 5.228446115719634 0.1429040966680053 DTS(ph)PSSGSAVSSSK ddPTM_PC-9_AZD4547_30min_R2 4 DTSPSSGSAVSSSK 14 0 F8WF16;B7Z8L1;F8W6A0;F8W0Q9;Q8NEY8-5;Q8NEY8-6;Q8NEY8-9;Q8NEY8-8;Q8NEY8-2;Q8NEY8-3;Q8NEY8;Q8NEY8-7 F8WF16 PPHLN1 Periphilin-1 1 DT(0.258)S(0.737)PS(0.002)S(0.002)GS(0.001)AVSSSK;DT(0.304)S(0.678)PS(0.013)S(0.001)GS(0.003)AVSSSK;DT(0.082)S(0.885)PS(0.025)S(0.006)GS(0.002)AVSSSK;DT(0.122)S(0.833)PS(0.01)S(0.013)GS(0.021)AVSSSK 110.55 0.00048431 476927100.0 92415.0 80350.0 122477.0 157619.0 147001.0 130144.0 107896.0 148839.0 104946.0 120729.0 True False 121801.0476485862 106321.56617011083 120852.87495494979 121282.37473927464 126592.448571962 122006.07510644897 117498.53497775215 125839.35252996693 110493.23130849462 116502.31445704777 1.0454817847716835 0.9126133387616914 1.0373431250544467 1.041029745241578 1.086608872638614 1.0472416421514985 1.008551079224024 1.0801446573523785 0.9484209118371757 1.0 16.82999909045403 DTS(ph)PSSGSAVSSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DTSPSSGSAVSSSK 14 0 F8WF16;B7Z8L1;F8W6A0;F8W0Q9;Q8NEY8-5;Q8NEY8-6;Q8NEY8-9;Q8NEY8-8;Q8NEY8-2;Q8NEY8-3;Q8NEY8;Q8NEY8-7 F8WF16 PPHLN1 Periphilin-1 1 DT(0.044)S(0.955)PS(0.001)SGSAVSSSK;DT(0.389)S(0.606)PS(0.005)SGSAVSSSK 96.70700000000001 0.0028829 63832000.0 60143.0 77263.0 84443.0 80266.0 90423.0 91459.0 87145.0 71460.0 85643.0 76700.0 True False 70324.0220216036 84933.16002662184 86456.44137186081 75768.95624588305 72705.26225693674 86662.7290356322 78889.99472483649 69584.25071812845 86895.3668543624 90605.1028431341 0.7761596181106551 0.9373993004971015 0.954211613462258 0.8362548451279054 0.8024411426673439 0.9564883910089769 0.8707014533322683 0.7679948317988298 0.9590559927381307 1.0 16.467304684116456 -8.508105472832026 23.359468505882834 1.0000000197087846 0.8684218983722675 0.3381629923866688 0.06623047954895762 305.5757119660776 483174.9554754616 0.06420412739654367 0.016577434433617744 3.103805705804411e-09 8.508105472832026 -0.13157812133651714 DTS(ph)PSSGSAVSSSK ddPTM_PC-9_Lapatinib_30min_R1 4 DTSPSSGSAVSSSK 14 0 F8WF16;B7Z8L1;F8W6A0;F8W0Q9;Q8NEY8-5;Q8NEY8-6;Q8NEY8-9;Q8NEY8-8;Q8NEY8-2;Q8NEY8-3;Q8NEY8;Q8NEY8-7 F8WF16 PPHLN1 Periphilin-1 1 DT(0.284)S(0.712)PS(0.002)S(0.002)GS(0.001)AVSSSK;DT(0.094)S(0.829)PS(0.068)S(0.004)GS(0.001)AVSS(0.001)S(0.001)K;DT(0.004)S(0.917)PS(0.021)S(0.044)GS(0.013)AVSSSK;DT(0.042)S(0.954)PS(0.003)SGSAVSSSK 126.56 3.1506999999999995e-05 20545600.0 95294.0 81467.0 91799.0 75822.0 99499.0 93453.0 78618.0 82104.0 103745.0 78958.0 True False 93935.09008522077 81278.36816681764 84251.64057438743 81398.20281477713 93646.66444256059 89456.23303958323 82688.45535917171 85918.85157538803 92060.14561671806 92605.7850950785 1.0143544486856568 0.8776813250205591 0.9097880924813297 0.8789753548464113 1.0112398955034334 0.9659896835574405 0.8929080972023005 0.927791406197518 0.994107933129661 1.0 16.49881470119137 -8.26960875718538 12.6153409641173 0.9970781982062276 0.932424585150731 0.2182266875710328 0.04692270325597819 1.303742964590386 1974.6839792281087 0.04044904928273961 0.011919400368093101 5.375158101202463e-09 8.26960875718538 -0.06465361305549655 DTSATSQSVNGS(ph)PQAEQPSLESTSK ddPTM_PC-9_AZD4547_30min_R2 1 DTSATSQSVNGSPQAEQPSLESTSK 25 0 C9J0I9;Q86WB0;Q86WB0-2;Q86WB0-3;F8WAU5 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 DTSATSQSVNGS(1)PQAEQPSLESTSK 196.75 1.8573e-25 10144000.0 50485.0 47384.0 68994.0 78390.0 74573.0 65851.0 58576.0 68204.0 57456.0 59946.0 True False 66538.17984676603 62699.95135537688 68079.0944801213 60318.39661342695 64219.82617367871 61733.326560077825 63789.150523251985 57664.6389720024 60493.006861251255 57847.308786142305 1.1502381224466864 1.0838870929531825 1.1768757425138867 1.0427174207260028 1.110161000075132 1.0671771575113698 1.102715957955387 0.9968422072180536 1.0457358886804902 1.0 15.819962222353267 -7.231737402485454 0.3862474234108931 0.9941526501599857 1.1411345965493098 0.5414780167767165 0.038153148744837495 0.9874248770825323 0.3517586375605073 0.041318155570676675 0.051520443237754884 5.8649268195462776e-08 7.231737402485454 0.14698194638932416 DTSATSQSVNGS(ph)PQAEQPSLESTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DTSATSQSVNGSPQAEQPSLESTSK 25 0 C9J0I9;Q86WB0;Q86WB0-2;Q86WB0-3;F8WAU5 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 DTSATSQSVNGS(1)PQAEQPSLESTSK;DTSATSQS(0.002)VNGS(0.998)PQAEQPSLESTSK 151.02 2.0945e-08 16270800.0 69164.0 68845.0 74638.0 82648.0 93387.0 79154.0 85429.0 86392.0 79967.0 64624.0 True False 80872.09914873217 75679.47661924553 76417.65298619134 78017.50050843133 75088.48773418884 75003.02489734678 77336.54666760073 84124.30153989054 81136.36609229934 76339.81963669753 1.0593697959152095 0.9913499531359311 1.0010195642308852 1.0219764846146862 0.9836083984942091 0.9824888931397457 1.013056449905785 1.1019714474076503 1.062831514122363 1.0 16.220148157541885 -7.615003908085412 8.506432635530775 1.0615745281038678 1.0047205806852275 0.31813802967614013 0.03137547503047973 0.257305767882048 21.150695105682754 0.014304749423912876 0.0082282625601465 2.426588258846315e-08 7.615003908085412 -0.05685394741864025 DTSATSQSVNGS(ph)PQAEQPSLESTSK ddPTM_PC-9_Lapatinib_30min_R1 2 DTSATSQSVNGSPQAEQPSLESTSK 25 0 C9J0I9;Q86WB0;Q86WB0-2;Q86WB0-3;F8WAU5 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 DTSATSQS(0.001)VNGS(0.999)PQAEQPSLESTSK;DTSATSQS(0.002)VNGS(0.998)PQAEQPSLESTSK 181.59 1.1982e-15 15937500.0 97202.0 95036.0 98098.0 84274.0 101021.0 105131.0 86659.0 86972.0 107775.0 83541.0 True False 95815.88165533614 94815.94998099464 90032.76110923044 90471.7910898229 95079.14339492773 100634.79220233069 91145.7789942565 91013.03662689608 95636.24457893659 97980.9505386145 0.9779031651420333 0.9676977969674572 0.918880257992071 0.9233610267351691 0.970383966192049 1.0270852818749732 0.9302397914412532 0.9288850141439243 0.9760697773721448 1.0 16.580213667196887 -5.007117834623225 23.888370856037866 0.9563749509377775 0.975351852632781 0.022498019362098054 0.03380570673187336 734.3756629124667 2464790.256249715 0.008861062383135386 0.029632020363639332 9.837441559055674e-06 5.007117834623225 0.018976901695003545 DTSEDIEELVEPVAAHGPK ddPTM_PC-9_Lapatinib_30min_R1 1 DTSEDIEELVEPVAAHGPK 19 0 A0A087WW66;Q99460-2;Q99460 A0A087WW66 PSMD1 26S proteasome non-ATPase regulatory subunit 1 0 185.33 6.2852e-11 2640500.0 25978.0 27504.0 23989.0 25120.0 27022.0 26249.0 23355.0 21431.0 27004.0 23053.0 False True 25607.548956218256 27440.316177840738 22016.717020217875 26967.40859786349 25432.619087296036 25126.391459407594 24564.207623107348 22426.762497711978 23962.525155273535 27037.68033380835 0.9471059883860734 1.0148916563500059 0.8142975561660081 0.9974009702357125 0.9406361334738721 0.9293101756214327 0.9085175695487409 0.8294632609317891 0.886264089945261 1.0 14.722683762143486 -7.276502490806799 3.1667588919674934 0.8902159412019897 0.9417094173867622 0.05017369824192519 0.06377544859656357 0.5765066119078898 11.920735262639477 0.02757036359024434 0.01870687914967018 5.290509629377477e-08 7.276502490806799 0.05149347618477251 DTSFTVCPDVPRT(ph)PVGK ddPTM_PC-9_AZD4547_30min_R2 2 DTSFTVCPDVPRTPVGK 17 1 D6RJC2;P30307-4;P30307-3;P30307-2;P30307;A0A3B3IT42;D6RD20 D6RJC2;D6RD20 CDC25C M-phase inducer phosphatase 3 1 DT(0.001)S(0.001)FT(0.004)VCPDVPRT(0.995)PVGK;DTSFTVCPDVPRT(1)PVGK 83.77600000000001 0.0025888 29268000.0 65058.0 57696.0 73267.0 110998.0 106674.0 109923.0 78100.0 149835.0 103225.0 108032.0 True False 85745.09070953555 76345.10369322615 72295.43170819264 85409.12600200497 91864.15642727273 103049.49743304502 85050.74870025225 126681.44361577 108681.26276198582 104249.83256238153 0.8224961959361131 0.7323283099523674 0.6934824731246656 0.8192735077142443 0.8811923642400346 0.9884859754703371 0.815835830233676 1.2151716746400119 1.0425077920096666 1.0 16.66968554096895 -6.8466485666257775 0.8342651913023585 1.0721301781265862 0.7444377632746086 0.6208958045182554 0.09300834746164403 0.3899149331876693 0.5840217676817681 0.06304416888879773 0.05461226030056289 1.4234802088481087e-07 6.8466485666257775 -0.32769241485197753 DTSFTVCPDVPRT(ph)PVGK ddPTM_PC-9_Lapatinib_30min_R1 3 DTSFTVCPDVPRTPVGK 17 1 D6RJC2;P30307-4;P30307-3;P30307-2;P30307;A0A3B3IT42;D6RD20 D6RJC2;D6RD20 CDC25C M-phase inducer phosphatase 3 1 DTSFTVCPDVPRT(1)PVGK;DTSFTVCPDVPRT(1)PVGK;DTSFTVCPDVPRT(1)PVGK 110.56 0.00027671 52240000.0 166027.0 110940.0 126421.0 101557.0 209779.0 186703.0 203103.0 143271.0 221957.0 184865.0 True False 163659.42453437689 110683.12524613322 116027.15337917212 109025.84056422066 197440.21166138258 178718.14791595037 213618.67954938882 149927.8936964997 196957.86534917247 216818.66893287117 0.7548216458475132 0.5104870617963327 0.5351345156311013 0.5028434179622049 0.9106236683083396 0.824274721339992 0.98524117226975 0.6914897800747896 0.9083990152626213 1.0 17.726129458145643 -6.26462433125392 24.974698726147388 0.8730545454228378 0.5682486733588604 0.6765552545729855 0.10498913473667366 162.02147523437296 1270484.2480864858 0.031175436881762216 0.03685367938811581 5.437204513564569e-07 6.26462433125392 -0.30480587206397736 DTSGGIDLGEEQHPLGT(ph)PTPGR ddPTM_PC-9_AZD4547_30min_R2 1 DTSGGIDLGEEQHPLGTPTPGR 22 0 Q9UIF8-4;Q9UIF8-2;Q9UIF8-5;Q9UIF8-3;Q9UIF8 Q9UIF8-4 BAZ2B Bromodomain adjacent to zinc finger domain protein 2B 1 DTSGGIDLGEEQHPLGT(0.796)PT(0.203)PGR 72.568 0.0027645 4858600.0 7990.9 6197.5 10535.0 13144.0 16768.0 14170.0 10517.0 11354.0 10205.0 13963.0 True False 10531.83997895459 8200.720676282046 10395.299016553286 10113.853872775659 14440.052636748478 13283.947659964213 11452.992625871368 9599.500188964208 10744.415466079592 13474.159620006429 0.7816324190873408 0.6086257627604187 0.7714988770890282 0.7506111073345614 1.0716848429870083 0.9858832041918377 0.8499968049113777 0.7124377667836792 0.7974089493586143 1.0 13.71790767480127 -6.026594078142521 23.94703667173414 0.8919476824700925 0.7180005046759302 0.3900252447983008 0.10705130592901906 505.7792373488355 455436.2181994264 0.034657376249398124 0.04491407484905787 9.406020519947887e-07 6.026594078142521 -0.17394717779416224 DTSGGIDLGEEQHPLGT(ph)PTPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DTSGGIDLGEEQHPLGTPTPGR 22 0 Q9UIF8-4;Q9UIF8-2;Q9UIF8-5;Q9UIF8-3;Q9UIF8 Q9UIF8-4 BAZ2B Bromodomain adjacent to zinc finger domain protein 2B 1 DTSGGIDLGEEQHPLGT(0.925)PT(0.075)PGR;DTSGGIDLGEEQHPLGT(0.749)PT(0.251)PGR 73.722 0.0022061999999999997 8216100.0 30520.0 25581.0 26424.0 33100.0 35083.0 31703.0 28106.0 29633.0 24874.0 26312.0 True False 35686.433202522996 28120.51262106066 27054.04837357805 31245.514311647894 28208.73799542275 30040.438870058144 25443.596210181346 28855.16514875882 25237.735193015244 31082.15731432262 1.1481324427271569 0.9047156005514059 0.8704044606682297 1.0052556518414506 0.9075540577881381 0.9664850018700455 0.8185917069037215 0.9283514286655513 0.8119685817749119 1.0 14.9237990196742 -4.760589211748784 24.959532204358535 0.9105194162879464 1.1481327242943078 0.5535075506367465 0.06344014310304208 14.847432017307137 435639.11431137304 0.015063673617364876 0.08831249766545643 1.735444735287321e-05 4.760589211748784 0.23761330800636138 DTSGGIDLGEEQHPLGT(ph)PTPGR ddPTM_PC-9_Lapatinib_30min_R1 1 DTSGGIDLGEEQHPLGTPTPGR 22 0 Q9UIF8-4;Q9UIF8-2;Q9UIF8-5;Q9UIF8-3;Q9UIF8 Q9UIF8-4 BAZ2B Bromodomain adjacent to zinc finger domain protein 2B 1 DTSGGIDLGEEQHPLGT(0.781)PT(0.218)PGR 72.122 0.0029808000000000005 5052200.0 10011.0 12475.0 15776.0 13872.0 14236.0 18816.0 13958.0 12604.0 20755.0 12616.0 True False 9868.241304207439 12446.114903961718 14478.958177121072 14892.193155635432 13398.666469052867 18011.2835422383 14680.676942981472 13189.627853164184 18417.353340160822 14796.658790236685 0.6669236240494255 0.8411436041340676 0.9785288950958819 1.0064564822878652 0.9055197297577573 1.2172534217064415 0.992161619126357 0.8913923095845887 1.2446967657531705 1.0 13.852983819528504 -4.197611163980666 0.7602927683629694 1.0454257273466872 7.510848116423936e-11 0.5513607405617473 0.10758404556987003 4.478362707521987 1.0518809534737987 0.0401481782355184 4.8975370603925255 6.344374867062534e-05 4.197611163980666 -1.0454257272715786 DTSGPTPGT(ph)PSPAMAR ddPTM_PC-9_Lapatinib_30min_R1 1 DTSGPTPGTPSPAMAR 16 0 Q9H6K5;Q9H6K5-2 Q9H6K5 PRR36 Proline-rich protein 36 1 DTSGPT(0.003)PGT(0.499)PS(0.499)PAMAR 139.21 6.595999999999999e-07 0.0 18767.0 11529.0 13088.0 13824.0 11235.0 10228.0 10768.0 10866.0 11995.0 8371.2 True False 18499.37913855369 11502.305308839646 12011.955161141013 14840.663075512131 10574.179388859862 9790.57228263252 11325.51435177135 11370.874028283246 10643.996787050293 9818.150766077142 1.8842019825638863 1.1715348015006506 1.2234437469267352 1.511553797563219 1.0770031588224218 0.9971910715060611 1.1535282581830302 1.1581482398468501 1.0841142126098273 1.0 13.261235605348713 -2.7508712103329915 1.3736514955356876 1.1485774336582275 199.99999999532037 0.6989603266118607 0.1423756849439295 233.77086550338007 2.1362417456836664 0.042806905150574844 144842.10484611083 0.0017747156933235807 2.7508712103329915 198.85142256166213 DTSGPTPGTPS(ph)PAMAR ddPTM_PC-9_AZD4547_30min_R2 2 DTSGPTPGTPSPAMAR 16 0 Q9H6K5;Q9H6K5-2 Q9H6K5 PRR36 Proline-rich protein 36 1 DTSGPT(0.012)PGT(0.06)PS(0.927)PAMAR;DT(0.002)S(0.033)GPT(0.073)PGT(0.085)PS(0.807)PAMAR 128.74 1.7508e-05 5094200.0 9689.6 15564.9 28340.0 39938.0 29917.0 36349.0 30562.0 35581.0 33358.0 31066.0 True False 12770.691243799618 20595.949536791035 27964.193082972957 30730.91113594907 25763.540955009783 34076.091283841844 33281.95879356097 30082.774020040142 35121.23577829326 29978.388795754465 0.42599658476669705 0.6870265669417107 0.9328117422685919 1.0251021609373876 0.8594037901949692 1.1366885497417958 1.1101983839196305 1.0034820158280309 1.1715518141277534 1.0 14.87163522651638 -4.701493603519984 0.8796070754888473 1.0628168289920852 9.505026818380864e-16 0.8658234343204124 0.07946769611049516 0.8670773575563374 0.47511698154335175 0.028327674105135807 0.9225235026877563 1.988412096388407e-05 4.701493603519984 -1.0628168289920843 down DTSGPTPGTPS(ph)PAMAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DTSGPTPGTPSPAMAR 16 0 Q9H6K5;Q9H6K5-2 Q9H6K5 PRR36 Proline-rich protein 36 1 DTSGPTPGT(0.035)PS(0.965)PAMAR 127.03 2.2941e-05 4573000.0 9324.1 11495.0 19195.0 16636.0 25162.0 15945.0 21452.0 16978.0 18234.0 17838.0 True False 10902.485970630561 12636.14763219155 19652.68159744287 15703.938854639699 20231.686726928347 15108.816130431735 19419.91126096956 16532.34548967796 18500.637754661104 21071.888194469688 0.5173948281242265 0.5996685022041786 0.9326492916093162 0.7452554184850503 0.9601269017855812 0.7170129221925655 0.9216028047294931 0.784568774146062 0.8779772170353767 1.0 14.363031975467598 -5.146610937377951 4.571678090843667 0.8548239933157673 0.5367371416429568 0.6556693640299665 0.08974502343487221 0.12124562310825092 3.9564569732966577 0.020916877918702347 0.061074903760895374 7.1349192550096335e-06 5.146610937377951 -0.3180868516728105 DTSGPTPGTPS(ph)PAMAR ddPTM_PC-9_Lapatinib_30min_R1 3 DTSGPTPGTPSPAMAR 16 0 Q9H6K5;Q9H6K5-2 Q9H6K5 PRR36 Proline-rich protein 36 1 DTSGPT(0.005)PGT(0.001)PS(0.994)PAMAR;DTSGPTPGTPS(1)PAMAR;DTSGPT(0.003)PGT(0.057)PS(0.94)PAMAR 143.97 2.1923000000000003e-05 8063300.0 50594.0 46209.0 43371.0 38560.0 37967.0 33673.0 29503.1 36395.0 42794.0 27100.8 True False 49872.52028219671 46102.00589957252 39805.20379690148 41395.831032389186 35733.855705993956 32232.884285596858 31030.626158223004 38086.04456647973 37974.08907920219 31785.137170453883 1.569051598385301 1.450426520179595 1.2523212841095652 1.3023643978755264 1.124231602788571 1.0140866818583114 0.9762621439012621 1.1982343937116278 1.1947121346545986 1.0 14.95606469402148 -5.249013034549941 0.7943292162925051 1.0811250926862122 1.683662469131838 0.8055177489416753 0.08153822756642967 0.6934845906731085 0.5240622800177561 0.03715672959820221 0.32828656091031166 5.63620739532446e-06 5.249013034549941 0.6025373764456259 DTSGTS(ph)RGVGFARMES(ph)T(ph)EK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DTSGTSRGVGFARMESTEK 19 2 F8W1T6;Q15434;F8VV01 F8W1T6 RBMS2 RNA-binding motif, single-stranded-interacting protein 2 3 DT(0.054)S(0.055)GT(0.05)S(0.859)RGVGFARMES(0.988)T(0.994)EK 50.178000000000004 0.027127 8207000.0 20174.0 32005.0 75269.0 39240.0 61622.0 42553.0 36704.0 28595.0 44176.0 30927.0 True False 23589.05974533746 35182.24488632368 77063.6984192722 37041.51001779646 49547.611457228304 40321.44576972479 33227.13140605193 27844.41154890691 44821.99042721882 36533.82028200269 0.6456773357742145 0.9630048162155977 2.1093796877638704 1.013896431631703 1.3562121638189717 1.1036744982727131 0.9094896495787574 0.7621543910266521 1.2268629472976045 1.0 15.156945001405024 -7.017278032964135 4.659063926723499 0.9585162485554853 1.2419504980957399 0.08489062045629092 0.36960552537994434 0.48269498781282605 27.093832217496004 0.1449764295644957 0.11777211393392054 9.609968564514875e-08 7.017278032964135 0.28343424954025453 DTSLYRPALEELRR ddPTM_PC-9_Lapatinib_30min_R1 1 DTSLYRPALEELRR 14 2 Q13200;C9JPC0;H7C2Q3 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 0 81.565 0.041602999999999994 3210800.0 20993.0 16618.0 21370.0 16043.0 17777.0 20018.0 14002.0 13911.0 18692.0 16389.0 False True 20693.635970355288 16579.522042006884 19613.041090585517 17222.855737879137 16731.391810926732 19161.876804237163 14726.955047687827 14557.35584460226 16586.710124513887 19221.816813030207 1.0765702415979406 0.8625366791950619 1.0203531373418409 0.8960056120295559 0.8704375852538949 0.9968816678789483 0.7661583288893183 0.7573350628715818 0.862910633570807 1.0 14.230457083157145 -6.133156718247257 0.7672508792785993 0.84452624949225 0.9928469427096037 0.20696062689820105 0.09159527617472525 1.123983916196164 1.3770857721211296 0.04971331160203214 0.10266153254799538 7.359414798644697e-07 6.133156718247257 0.14832069321735375 DTSPDKGELVSDEEEDT(ph) ddPTM_PC-9_AZD4547_30min_R2 1 DTSPDKGELVSDEEEDT 17 1 Q9UPU7 Q9UPU7 TBC1D2B TBC1 domain family member 2B 1 DTSPDKGELVS(0.348)DEEEDT(0.652) 103.77 0.0085812 9154600.0 30442.0 28631.0 35852.0 44330.0 39462.0 37512.0 35786.0 37031.0 37352.0 38082.0 True False 40121.92276706451 37885.410840279335 35376.57905471934 34110.40339167265 33983.3824637028 35166.36870999133 38970.88467333201 31308.709837725368 39326.35046438065 36748.76077125868 1.0917898161737194 1.030930296564167 0.9626604628906962 0.928205541514491 0.9247490731791236 0.9569402606222045 1.0604679955306482 0.8519664114010616 1.0701408602365148 1.0 15.165407980265702 -5.0029445913680926 2.5125554978857645 0.9637885358948234 1.0947261208473258 0.28653962563842794 0.06117013731115703 0.4000344784385855 4.373358449168222 0.015354540555682356 0.09153206148227266 9.932427613180138e-06 5.0029445913680926 0.1309375849525024 DTSS(ph)SPTTGSTVQSVDLIFTR ddPTM_PC-9_Lapatinib_30min_R1 1 DTSSSPTTGSTVQSVDLIFTR 21 0 P57060 P57060 RWDD2B RWD domain-containing protein 2B 1 DT(0.006)S(0.096)S(0.349)S(0.349)PT(0.197)T(0.003)GSTVQSVDLIFTR 88.471 0.0010084 0.0 3760.8 3965.2 5350.4 4341.4 3601.4 4007.6 3951.4 3521.3 2984.5 2884.1 True False 3707.170302353747 3956.018823021164 4910.510765141262 4660.681038485847 3389.572732624826 3836.2042901718887 4155.984157651309 3684.9124531376588 2648.3541818217263 3382.6128421783123 1.0959487459305064 1.1695156991343985 1.451691634322249 1.3778346077242742 1.0020575486380616 1.1340949937686264 1.2286313425614994 1.0893686700381215 0.7829315104581277 1.0 11.723922347211458 -8.037456224464561 4.1182146269437725 0.8947806293706635 1.2105146908469824 0.4737580132991498 0.1323075717144406 0.20302452216112918 7.403454175757028 0.10023392274863453 0.037426969552337735 9.173683986161608e-09 8.037456224464561 0.3157340614763189 DTSSITSCGDGNVVKQEQLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 DTSSITSCGDGNVVKQEQLSPK 22 1 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 DTSSITSCGDGNVVKQEQLS(1)PK;DTSSITSCGDGNVVKQEQLS(1)PK 117.53 6.1219e-07 18928100.0 39226.0 24411.0 38213.0 66322.0 67536.0 46493.0 32646.0 32046.0 30136.0 49640.0 True False 51699.052048514284 32301.37836687711 37706.27065206933 51032.48756468557 58159.79215621688 43585.78536024815 35551.430756318034 27094.027043821297 31728.927436136622 47902.11870924006 1.0792644133826552 0.6743204525658351 0.7871524614796631 1.065349277647748 1.2141381993819444 0.9098926422191987 0.7421682321007725 0.5656122896834417 0.6623700222682695 1.0 15.547801847279484 -7.260060183590106 4.25839001777157 0.7026425476765863 0.9533821976162568 0.2503202736872885 0.17662566258789672 0.28558001484133927 13.085262134565632 0.07828216763240305 0.055349849018160494 5.494647249481484e-08 7.260060183590106 0.25073964993967046 DTSSITSCGDGNVVKQEQLS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DTSSITSCGDGNVVKQEQLSPK 22 1 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 DTSSITSCGDGNVVKQEQLS(1)PK;DTSSITSCGDGNVVKQEQLS(1)PK 100.7 4.2653999999999995e-05 11932800.0 46806.0 15556.0 25594.0 60098.0 52602.0 57992.0 56910.0 80449.0 63852.0 45818.0 True False 54729.3313393608 17100.296873977542 26204.258025785526 56730.90390034488 42295.0157066165 54950.797430918625 51519.0728072803 78337.29899276137 64785.71470388394 54124.44070491155 1.011175923973924 0.3159440846180563 0.48414833824615594 1.0481568615118606 0.7814402357931141 1.0152677185250265 0.9518633751462522 1.4473553531917165 1.1969770746842088 1.0 15.723992591371823 -6.622196203037174 0.8544842023836194 1.210847672349206 0.6067079006956957 0.4430409306884343 0.23241171526241935 0.5194499516609749 0.8353891383551336 0.1412527818953473 0.15423280375919232 2.386732775047666e-07 6.622196203037174 -0.6041397716535104 DTSSITSCGDGNVVKQEQLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 DTSSITSCGDGNVVKQEQLSPK 22 1 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 DTSSITSCGDGNVVKQEQLS(1)PK;DTSSITSCGDGNVVKQEQLS(1)PK 104.77 2.0130999999999998e-05 29409000.0 138173.0 69822.0 74771.0 89872.0 69944.0 66427.0 43425.0 42905.0 77738.0 52271.0 True False 136202.6276821751 69660.33144885083 68623.61700440664 96481.48668420324 65830.03143519483 63586.072058900056 45673.33401984313 44898.52293240315 68982.32782256903 61305.97270327055 2.2216861045727927 1.136273161931816 1.1193626653075794 1.573769772012053 1.0737947467830151 1.0371921242758109 0.7450062694691826 0.7323678420325905 1.1252138214404184 1.0 15.903740014144663 -2.2054194132819678 0.9658873805014988 1.0068908688847762 199.99999999999997 0.6981319697307654 0.22668685862923307 185.76698712471716 1.3394950191563015 0.0800339297397613 80409.87548612674 0.006231327638315526 2.2054194132819678 198.9931091311152 DTSSS(ph)PTTGSTVQSVDLIFTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DTSSSPTTGSTVQSVDLIFTR 21 0 P57060 P57060 RWDD2B RWD domain-containing protein 2B 1 DTS(0.003)S(0.015)S(0.977)PT(0.004)T(0.001)GSTVQSVDLIFTR 135.43 5.288199999999999e-09 0.0 3485.4 2821.8 5554.9 3359.2 4184.1 2276.3 3354.6 3927.2 2361.0 1875.2 True False 4075.4093802121156 3101.9296553734803 5687.349883075563 3170.994914673342 3364.2556408131663 2156.926820802871 3036.8280027992005 3824.115161212353 2395.525158426832 2215.1589159249665 1.8397819456264062 1.4003192425940383 2.5674681135464907 1.431497709657212 1.5187423424239432 0.9737120011104125 1.3709300858584839 1.7263389699585265 1.0814236130894255 1.0 11.113194486373683 -5.9750322669274265 24.999573754941288 1.3197571893108515 1.9018330240206809 0.4190069304087345 0.34420252882767316 235.7652497687088 236064.22203414133 0.09504644225234873 0.1409711682948885 1.0591750283601919e-06 5.9750322669274265 0.5820758347098294 DTSSS(ph)PTTGSTVQSVDLIFTR ddPTM_PC-9_Lapatinib_30min_R1 1 DTSSSPTTGSTVQSVDLIFTR 21 0 P57060 P57060 RWDD2B RWD domain-containing protein 2B 1 DTS(0.001)S(0.044)S(0.925)PT(0.025)T(0.004)GSTVQSVDLIFTR 136.61 3.3879e-10 0.0 1311.5 3461.0 4721.9 3814.2 4988.1 3372.1 4183.2 3541.5 2667.0 4157.2 True False 1292.797769500356 3452.986267143206 4333.683609061105 4094.708991798206 4694.709764981918 3227.883143749031 4399.785627445202 3706.0510188813846 2366.6143752449457 4875.766480879193 0.26514759773057056 0.7081935282759003 0.888820993797812 0.8398082656041912 0.9628659993034311 0.6620257874136299 0.9023782506195492 0.7600960861056482 0.4853830437790368 1.0 12.251413316086772 -4.775267709909549 3.3974204943345447 0.8082077052930012 0.19099192339713372 0.5658587721916276 0.14329952716903255 0.2271863010776903 4.1734830777993315 0.035633474523258865 0.3713624702484406 1.6777694805026937e-05 4.775267709909549 -0.6172157818958675 DTT(ph)SPMELAALEK ddPTM_PC-9_AZD4547_30min_R2 1 DTTSPMELAALEK 13 0 Q6VY07-2;Q6VY07 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 DT(0.09)T(0.519)S(0.391)PMELAALEK 89.507 0.023197 5263300.0 34362.0 36330.0 41466.0 43448.0 43036.0 38751.0 40355.0 48100.0 33923.0 37110.0 True False 45288.40122599927 48072.96202812854 40916.13374659691 33431.73486490849 37061.19425543342 36327.893844126556 43946.51682200618 40667.2502280411 35716.10052482289 35810.790195404894 1.2646579698152125 1.3424155615057352 1.1425643925569426 0.9335659638473525 1.0349169636639006 1.0144398837864241 1.227186459226617 1.1356144336982368 0.997355834091755 1.0 15.128106732846653 -5.429674825380079 4.432234238784609 1.0585369139081293 1.2997543850851032 0.6132830999624326 0.07965389292967273 0.1569090735882021 5.257031611688323 0.02278593629907293 0.04920766895670938 3.7181351738413596e-06 5.429674825380079 0.2412174711769739 DTT(ph)SPMELAALEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DTTSPMELAALEK 13 0 Q6VY07-2;Q6VY07 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 DT(0.021)T(0.489)S(0.489)PMELAALEK 81.904 0.04245 4328900.0 28084.0 26705.0 25261.0 28205.0 33193.0 24973.0 30832.0 21315.0 21685.0 16853.0 True False 32838.066515716135 29356.095912803423 25863.318042875984 26624.76529184376 26689.069927944227 23663.37191754605 27911.369755650445 20755.50383510932 22002.102101010532 19908.315491725396 1.649464844444765 1.4745645318412228 1.29912136733144 1.3373690658514006 1.340599104883442 1.1886174863655035 1.4019955514192752 1.0425544965738587 1.105171460144651 1.0 14.281083534583447 -1.5228787454160337 0.16098082170696495 0.9497295929207432 3.4493959875391553 0.7781904266151123 0.09060596234978305 30.363395292936644 0.3158984011628452 0.27398213316569214 18.018636853147243 0.02999999999062644 1.5228787454160337 2.499666394618412 DTTIINHS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 DTTIINHSR 9 0 Q8IY63-2;Q8IY63 Q8IY63-2 AMOTL1 Angiomotin-like protein 1 1 DTTIINHS(1)R;DTTIINHS(1)R 77.67399999999999 0.017779 3527400.0 59598.0 52030.0 78709.0 100658.0 73711.0 88978.0 71797.0 99895.0 73272.0 83828.0 True False 78548.92428459068 68847.67999789506 77665.26723245298 77452.85325059739 63477.49999447558 83414.19159409264 78186.7939107812 84458.52310873526 77145.00833224722 80893.20723525746 0.9710200271346762 0.8510934644693833 0.960096278623039 0.9574704217789922 0.7847074206103276 1.0311643516804017 0.9665433796362488 1.0440743542669655 0.9536648498543326 1.0 16.303730941296735 DTTIINHS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DTTIINHSR 9 0 Q8IY63-2;Q8IY63 Q8IY63-2 AMOTL1 Angiomotin-like protein 1 1 DTTIINHS(1)R;DTTIINHS(1)R 97.779 0.0026489 4653300.0 92276.0 78830.0 109522.0 101783.0 90420.0 93771.0 98585.0 98280.0 84977.0 70725.0 True False 107896.50426592429 86655.72143067946 112133.41984449814 96080.42849493829 72702.85008540089 88853.48368558876 89246.31510640873 95700.2541362675 86219.62786431024 83546.88264120804 1.2914485957457642 1.037210709618243 1.3421616258987776 1.150018115069063 0.870204222910664 1.0635164458160564 1.0682183737444388 1.1454676836627418 1.0319909629013964 1.0 16.350298378009775 -6.010430580907456 24.76813063713949 1.0379826254339402 1.2118211134273693 0.4436802150949427 0.09826767762585213 449.3379173509345 1066988.5509666875 0.027940122471111318 0.038681750408248186 9.762688200550311e-07 6.010430580907456 0.17383848799342916 DTTIINHS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 2 DTTIINHSR 9 0 Q8IY63-2;Q8IY63 Q8IY63-2 AMOTL1 Angiomotin-like protein 1 1 DTTIINHS(1)R;DTTIINHS(1)R 82.505 0.0088848 8969100.0 69822.0 71262.0 78794.0 62506.0 68997.0 66295.0 54456.0 52214.0 60317.0 38729.0 True False 68826.32547621331 71096.99721732426 72315.86147363576 67102.89975390343 64938.73211332125 63459.7173911931 57275.46522474565 54640.05305657848 53523.46429383179 45423.25604685133 1.5152221893829703 1.5652113785940844 1.5920448635176292 1.4772807058281083 1.4296362208455706 1.3970754832224765 1.2609282162791122 1.202909210212068 1.1783273360814466 1.0 15.471143505107195 -7.478120344732673 0.49665240690032314 1.0070897057592316 1.587461501193952 0.9701544191263917 0.031718615667305224 0.14461689419720627 0.0792584384589134 0.03282758749478868 0.026188297560760097 3.325673847760372e-08 7.478120344732673 0.5803717954347203 DTTKLEPAS(ph)PPEDTSAEVSR ddPTM_PC-9_Lapatinib_30min_R1 1 DTTKLEPASPPEDTSAEVSR 20 1 E9PFE2;Q9UHL9-2;Q9UHL9;Q9UHL9-3 E9PFE2 GTF2IRD1 General transcription factor II-I repeat domain-containing protein 1 1 DT(0.007)T(0.007)KLEPAS(0.92)PPEDT(0.006)S(0.011)AEVS(0.049)R 48.51 0.029383999999999997 6446700.0 27377.0 19863.0 27806.0 20223.0 21635.0 22670.0 17835.0 15941.0 23096.0 20583.0 True False 26986.59895967308 19817.00844387908 25519.898014263974 21710.266881950378 20362.47183604655 21700.456946351107 18758.409032674783 16681.677055481618 20494.68526833795 24140.744124876484 1.117885961595691 0.8208946808502935 1.057129717387887 0.8993205333541664 0.8434898166649092 0.8989141690951143 0.7770435300436606 0.691017516659378 0.8489665920123252 1.0 14.559182526591979 -6.20243357779943 1.1917183568955263 0.8141849490123123 0.9889044633702344 0.2784845465825687 0.10500143793751408 0.5787275247584615 1.6857182795718437 0.041220373264368566 0.06410661186092653 6.274316497799298e-07 6.20243357779943 0.1747195143579221 DTTLIRHS(ph)PQPSPSSSFNEGLLTGGHR ddPTM_PC-9_Lapatinib_30min_R1 1 DTTLIRHSPQPSPSSSFNEGLLTGGHR 27 1 Q9Y2J4;Q9Y2J4-2;Q9Y2J4-4;Q9Y2J4-3 Q9Y2J4 AMOTL2 Angiomotin-like protein 2 1 DT(0.026)T(0.08)LIRHS(0.735)PQPS(0.094)PS(0.041)S(0.023)S(0.002)FNEGLLTGGHR 58.802 0.0011012 7770000.0 16341.0 11058.0 15284.0 12682.0 16208.0 10284.0 7436.8 9814.1 12960.0 6789.1 True False 16107.974343427619 11032.3958804015 14027.408517946142 13614.676585911819 15254.67730615403 9844.177293174895 7821.841115458139 10270.098914133496 11500.308325149806 7962.58688909289 2.022957434284609 1.38552910430574 1.761664734504915 1.7098308345697466 1.915794140601443 1.2363039085525582 0.9823241145628762 1.2897942662580455 1.4442929773115405 1.0 12.959021495048855 -6.808229918041352 8.63431151171561 1.1939452710155007 1.735508362282594 0.6711003383354472 0.19870337627393697 0.18200793472033103 30.715402497226425 0.06915973463477164 0.06124144540639952 1.5551421122973084e-07 6.808229918041352 0.5415630912670932 DTTS(ph)PMELAALEK ddPTM_PC-9_AZD4547_30min_R2 1 DTTSPMELAALEK 13 0 Q6VY07-2;Q6VY07 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 DT(0.003)T(0.028)S(0.97)PMELAALEK 74.133 0.017457 6315900.0 33094.0 30074.0 37185.0 40580.0 35276.0 46028.0 31055.0 42410.0 32724.0 32385.0 True False 43617.20360203771 39794.83237087636 36691.90260375262 31224.90795475018 30378.536308083225 43149.86188375672 33818.83483849342 35856.50898484869 34453.723832629934 31251.211007226837 1.3956964289144265 1.2733852893468292 1.1740953845042237 0.9991583349371461 0.9720754917644053 1.380742073444076 1.0821607786870346 1.147363824606889 1.1024764392222277 1.0 14.93162447589279 -5.10939173619474 2.13009437804048 1.1097296520499929 1.3941246496347002 0.431004859992275 0.11011936327375857 0.39283391819572855 3.0409751540702037 0.030987565885708016 0.1637130749725815 7.77335073878764e-06 5.10939173619474 0.2843949975847073 DTTS(ph)PMELAALEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DTTSPMELAALEK 13 0 Q6VY07-2;Q6VY07 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 DT(0.011)T(0.4)S(0.589)PMELAALEK 78.40100000000001 0.013243000000000001 4808300.0 38892.0 40491.0 38194.0 35129.0 39387.0 32412.0 41931.0 33166.0 31213.0 24758.0 True False 45475.647447985764 44510.67888430345 39104.689811551594 33160.83601975465 31669.400091945256 30712.257661934982 37958.99212584907 32295.42764228176 31669.431075805474 29246.429415779825 1.5549127998322254 1.5219183939181256 1.3370756906979138 1.1338422050885575 1.0828467175161602 1.050119904392988 1.297901757038704 1.1042519817771963 1.0828477769227558 1.0 14.835972881900748 -5.513271166910894 2.0558898309177085 1.1129227214176034 1.5523998714832967 0.8506064790957117 0.07320150864850522 0.12320570509239662 1.0177464328358443 0.021914512665473954 0.05680241704676276 3.067106335559117e-06 5.513271166910894 0.4394771500656933 DTTS(ph)PMELAALEK ddPTM_PC-9_Lapatinib_30min_R1 2 DTTSPMELAALEK 13 0 Q6VY07-2;Q6VY07 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 DT(0.001)T(0.182)S(0.817)PMELAALEK;DT(0.038)T(0.22)S(0.741)PMELAALEK 97.273 0.0026884 7139100.0 42496.0 52060.0 57288.0 48332.0 57710.0 59290.0 54836.0 54754.0 62291.0 44263.0 True False 41889.99924718806 51939.45826855685 52578.00177807505 51886.49651082557 54315.61126222545 56754.30491174053 57675.13976539134 57298.07072930434 55275.13162669032 51913.800573259825 0.8069145156897856 1.0004942365038525 1.01279430897913 0.9994740500188245 1.0462653603173637 1.0932411860628442 1.1109789521959814 1.1037155842297912 1.06474831386477 1.0 15.663830489846784 -3.79183665634014 0.7309478496814539 1.074130828317444 2.850960691187719e-17 0.7924737173527114 0.03807376592642245 4.648925080121988 0.6404753921036815 0.015301188518247272 5.745906044160656 0.0001614965851742186 3.79183665634014 -1.074130828317444 DTVATQLS(ph)EAVDATR ddPTM_PC-9_AZD4547_30min_R2 1 DTVATQLSEAVDATR 15 0 O60664-3;O60664;K7ERZ3;O60664-4;K7EL96 O60664-3 PLIN3 Perilipin-3 1 DTVAT(0.009)QLS(0.986)EAVDAT(0.005)R 87.429 0.0051657 1378400.0 7809.3 6121.2 11930.0 15224.0 9240.8 10879.0 8638.6 15411.0 10209.0 10502.0 True False 10292.49495646924 8099.758193409867 11771.800405076481 11714.342008455318 7957.874427818777 10198.73441021529 9407.418664814335 13029.584059549716 10748.62689791343 10134.328176560019 1.015607031581536 0.7992397771510925 1.1615767912769808 1.1559071113909414 0.7852394642424128 1.0063552543921201 0.9282725505744945 1.2856879935747707 1.0606156333849777 1.0 13.306962832590004 -7.731593878923664 24.999973184915277 1.1298642421732044 0.9794196869004439 0.1722964269124011 0.136048555205025 319.19793943613297 267375.0864269305 0.06430779870092704 0.03712188675619806 1.8552657240350827e-08 7.731593878923664 -0.15044455527276046 DTYMLSS(ph)TVSSK ddPTM_PC-9_AZD4547_30min_R2 1 DTYMLSSTVSSK 12 0 Q96G03;Q96G03-2 Q96G03 PGM2 Phosphoglucomutase-2 1 DT(0.012)Y(0.001)MLS(0.001)S(0.932)T(0.049)VS(0.004)S(0.001)K 61.03 0.032596 2954100.0 948.01 3921.2 30417.0 49774.0 31113.0 18698.0 7469.9 34870.0 11427.0 19067.0 True False 1249.4574601670317 5188.651216754686 30013.65070588524 38299.37330063418 26793.496999472543 17528.811104164484 8134.7066288862325 29481.642732885517 12031.007891317135 18399.470133543113 0.06790725227946706 0.2820000347344529 1.6312236432922556 2.0815476218965996 1.456210249806418 0.9526802118180906 0.4421163527995447 1.6023093338508196 0.6538779543104359 1.0 14.167376599814528 -5.168654193307833 5.813100948316912 1.2482295569157822 0.13485358942161238 0.44976582450568914 0.4664243662082255 0.2135542173143243 10.690330455388773 0.1284144894726537 0.3534095540955216 6.781812940838907e-06 5.168654193307833 -1.11337596749417 DVAEVDTVR ddPTM_PC-9_Lapatinib_30min_R1 2 DVAEVDTVR 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 138.06 0.0041905 7512700.0 33323.0 38241.0 45034.0 41173.0 46598.0 44831.0 44525.0 38029.0 44601.0 37931.0 False True 32847.80790931023 38152.45531402005 41331.47835626711 44200.99976910164 43857.19725519287 42913.68263616527 46830.2866375018 39795.96617169002 39577.56571064865 44487.322810119476 0.7383633321679312 0.857602860861332 0.9290619382217689 0.9935639408502975 0.9858358400747983 0.9646272224410805 1.0526658760155685 0.8945462135707047 0.8896369394843869 1.0 15.441106661142987 -4.896090665926794 1.544368778437597 0.968170486170598 0.6827184955184231 0.7096661543809744 0.04608571392130321 0.49038052167690815 1.3192339084467373 0.013953888038666278 0.20090563132180408 1.2703088802062565e-05 4.896090665926794 -0.28545199065217486 DVAEVDTVRR ddPTM_PC-9_AZD4547_30min_R2 2 DVAEVDTVRR 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 144.65 8.497200000000001e-05 18740000.0 70372.0 55147.0 87982.0 134392.0 95794.0 78775.0 66240.0 90584.0 83378.0 92136.0 False True 92748.83217146897 72972.18929163783 86815.30119358252 103410.00073570202 82494.65662480232 73849.18679701338 72135.2316761167 76586.32421324064 87785.19086043925 88910.34668401576 1.0431725398742966 0.8207390029754177 0.9764364264838719 1.1630817401175761 0.9278409060532112 0.8306028437777977 0.8113255022217242 0.8613882081173942 0.9873450518917075 1.0 16.44006369782987 -6.515901961991979 24.58840754313143 0.8835078897040861 0.9936491978491694 0.19211190151645863 0.09705939009047063 424.67185096328046 1496685.5748209902 0.032627983209621535 0.03389032142522862 3.0485831017159633e-07 6.515901961991979 0.11014130814508327 DVAEVDTVRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DVAEVDTVRR 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 128.35 0.00017883 5572700.0 34626.0 34084.0 39840.0 47856.0 58569.0 54577.0 44944.0 50838.0 44282.0 38739.0 False True 40487.49790532639 37467.63426669135 40789.936694041375 45174.783471245355 47092.8248910844 51714.88604268252 40686.57895361808 49503.55636731351 44929.54047668656 45762.074042244734 0.8847391372154771 0.8187486046218869 0.8913480769334583 0.9871664345794898 1.0290797757027184 1.1300817789626956 0.8890894874226796 1.0817594570039564 0.9818073463018825 1.0 15.481864819398556 -5.750778049045575 2.706443690029373 1.021111105571199 0.8514771824613598 0.5639820961037674 0.06116972360521878 0.18349600890143886 2.7416659877106766 0.017286543000311686 0.031242012316830138 1.7750964316015887e-06 5.750778049045575 -0.16963392310983916 DVAEVDTVRR ddPTM_PC-9_Lapatinib_30min_R1 2 DVAEVDTVRR 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 104.05 0.0016837 17610300.0 99750.0 83963.0 93415.0 94709.0 89497.0 81343.0 73169.0 72369.0 100693.0 69160.0 False True 98327.54670809054 83768.58883217124 85734.77929232808 101674.21579996249 84232.96241787182 77864.14950979433 76957.33280133344 75731.52793602333 89351.8939957029 81114.2138500925 1.2122110545238107 1.0327239192256032 1.0569636962860154 1.2534697801283878 1.038448854026288 0.9599322463223938 0.9487527419492542 0.9336406573080158 1.1015565553138995 1.0 16.307667123267635 -6.513037957687268 21.96122603753369 0.9840233013680941 1.1279820006179437 0.47302071585989247 0.07442549346490392 87.42280897057084 195099.24508634835 0.02390847542171301 0.025338352665344392 3.068753765120851e-07 6.513037957687268 0.1439586992498496 DVATSPIS(ph)PTENNTTPPDALTR ddPTM_PC-9_AZD4547_30min_R2 1 DVATSPISPTENNTTPPDALTR 22 0 H0YCM0;E9PM17;B3KNX7;Q13153;Q13153-2 H0YCM0 PAK1 Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase PAK 1 1 DVAT(0.01)S(0.042)PIS(0.936)PT(0.012)ENNTTPPDALTR 86.51899999999999 0.00029816 0.0 4374.8 6469.9 7693.1 10836.0 8705.9 9474.3 6923.2 9484.8 7551.3 7581.7 True False 5765.895398507119 8561.168649209712 7591.084467417755 8337.92761453112 7497.2360597726965 8881.870523274441 7539.3513879844695 8019.142099021295 7950.446301715506 7316.266990689876 0.788092534873913 1.1701553073587942 1.0375625270479591 1.139642337429912 1.0247351647107887 1.2139893930301933 1.0304915604608844 1.0960701829533892 1.0866807228102306 1.0 12.836892008616392 -4.75228214002613 24.99987876776129 1.0918897740532851 0.7880919466029551 0.6539007583098255 0.06559986358920548 201.51635803655518 550113.4577392556 0.014764215967595895 0.1783723197344054 1.7689593779757774e-05 4.75228214002613 -0.30379782745033 DVATSPISPT(ph)ENNTTPPDALTR ddPTM_PC-9_AZD4547_30min_R2 1 DVATSPISPTENNTTPPDALTR 22 0 H0YCM0;E9PM17;B3KNX7;Q13153;Q13153-2 H0YCM0 PAK1 Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase PAK 1 1 DVAT(0.005)S(0.024)PIS(0.471)PT(0.498)ENNT(0.001)TPPDALTR 75.773 0.025319 0.0 3719.8 5616.0 6356.5 8583.6 7828.5 6372.1 5240.0 7355.9 4687.4 5608.2 True False 4902.619023353475 7431.262173134322 6272.208656736684 6604.783635298023 6741.6479047462735 5973.65157967946 5706.349848774928 6219.21467676606 4935.166394483239 5411.858625003228 0.9059030109735269 1.3731441798574127 1.1589749643049745 1.2204279699368688 1.2457176677896409 1.103807766167561 1.0544159121990229 1.1491827683806781 0.9119170947449308 1.0 12.40190843667595 -7.691373042770882 0.9854258004220203 0.9765094769447834 1.188448987239499 0.2723822632491091 0.12059015376596667 0.6929153148656763 1.2223480802104338 0.09947879059558366 0.04224019040030424 2.0352930857621876e-08 7.691373042770882 0.21193951029471558 DVATSPISPTENNT(ph)TPPDALTR ddPTM_PC-9_AZD4547_30min_R2 1 DVATSPISPTENNTTPPDALTR 22 0 H0YCM0;E9PM17;B3KNX7;Q13153;Q13153-2 H0YCM0 PAK1 Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase PAK 1 1 DVATSPISPT(0.027)ENNT(0.962)T(0.011)PPDALTR 121.48 1.6161e-06 7853600.0 17092.0 14720.0 22097.0 34646.0 30192.0 25133.0 23104.0 26184.0 20608.0 20434.0 True False 22526.900464314647 19477.95213471105 21803.97934207668 26658.89997536409 26000.36195185534 23561.429536900527 25160.211241621368 22137.864448462107 21697.29680793417 19718.611879625543 1.1424181682682641 0.9877952998728496 1.1057563014669336 1.3519663624451004 1.3185695884972755 1.194882767647839 1.2759625979361362 1.1226887867972228 1.1003460558170994 1.0 14.26727037422329 -8.404924542501574 1.7748562178551497 1.0056901224644936 1.1946347999222673 0.26295404503933006 0.10162286829457183 0.5296326716843816 3.4934083953749933 0.10956298324174697 0.03167484944834297 3.93618459663758e-09 8.404924542501574 0.18894467745777366 DVATSPISPTENNT(ph)TPPDALTR ddPTM_PC-9_Lapatinib_30min_R1 2 DVATSPISPTENNTTPPDALTR 22 0 H0YCM0;E9PM17;B3KNX7;Q13153;Q13153-2 H0YCM0 PAK1 Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase PAK 1 1 DVATSPISPT(0.214)ENNT(0.707)T(0.071)PPDALT(0.007)R;DVATSPISPTENNT(0.572)T(0.417)PPDALT(0.01)R 125.54 3.0983e-06 5011700.0 33581.0 34811.0 41049.0 29274.0 32222.0 34900.0 30860.0 29168.0 36815.0 25154.0 True False 33102.128781998836 34730.39726828147 37674.1096737223 31426.907615201246 30326.7653108894 33407.40835587355 32457.77980086033 30523.251763019114 32668.50702086341 29501.83538440184 1.122036251327622 1.1772283593801105 1.2770090125864269 1.0652526260049986 1.027961986626897 1.1323840676548775 1.1001952718515051 1.0346221299559322 1.1073381230421973 1.0 14.848517090552967 -5.96568125515546 0.22672988586184267 1.0003142236396219 1.2642260112535812 0.3688053765428212 0.06121185343359179 7.598588771219323 0.5809065595749606 0.1324623297635971 0.5757818254763459 1.0822279471616211e-06 5.96568125515546 0.2639117876139594 DVATSPISPTENNTT(ph)PPDALTR ddPTM_PC-9_AZD4547_30min_R2 1 DVATSPISPTENNTTPPDALTR 22 0 H0YCM0;E9PM17;B3KNX7;Q13153;Q13153-2 H0YCM0 PAK1 Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase PAK 1 1 DVATSPIS(0.004)PT(0.066)ENNT(0.114)T(0.814)PPDALT(0.002)R 103.04 0.00012069 6761300.0 17696.0 15767.0 17976.0 26822.0 21044.0 23253.0 17313.0 26401.0 16806.0 21173.0 True False 23322.959900334194 20863.374409510117 17737.626494690263 20638.602295769088 18122.40384588115 21798.986234096516 18853.823460274878 22321.332084626043 17694.330849871007 20431.739714559644 1.141506314497256 1.0211256946780156 0.8681407820622559 1.0101245701100054 0.8869731162915675 1.0669177729668595 0.9227713216628174 1.0924831853021246 0.8660217434769902 1.0 14.318524430938732 -4.845966831536927 3.755895884953892 0.9673430958507568 1.1484553729923264 0.33374187305125713 0.0757590688520432 0.2546437190047692 6.039606185804769 0.017573352467705285 0.11214429229264704 1.4257164759861534e-05 4.845966831536927 0.18111227714156952 DVATSPISPTENNTT(ph)PPDALTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DVATSPISPTENNTTPPDALTR 22 0 H0YCM0;E9PM17;B3KNX7;Q13153;Q13153-2 H0YCM0 PAK1 Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase PAK 1 1 DVATSPISPT(0.002)ENNT(0.257)T(0.741)PPDALTR;DVATSPISPTENNT(0.32)T(0.68)PPDALTR 155.46 1.4733e-05 19536100.0 65586.0 70382.0 81588.0 86951.0 106556.0 86441.0 87183.0 75783.0 78776.0 60589.0 True False 76688.41441745334 77369.05982156646 83533.36734421311 82079.41736894533 85677.11671864642 81907.8817893164 78924.39508974012 73793.7765487258 79927.94997044992 71573.30607773994 1.071466704837661 1.0809764709978804 1.1671022609111092 1.1467881234910973 1.1970540612667453 1.1443914816559049 1.1027071322374817 1.0310237236851136 1.116728489300683 1.0 16.12713400097858 -8.201343503717634 0.8622802881933832 1.0146137255001482 1.135483854601543 0.41188696866547636 0.044692838333324596 0.5847766534978214 0.9064584643077801 0.045299757386142954 0.017041413495896315 6.290084739767072e-09 8.201343503717634 0.12087012910139494 DVDAS(ph)PSPLSVQDLK ddPTM_PC-9_Lapatinib_30min_R1 1 DVDASPSPLSVQDLK 15 0 Q8IWZ8 Q8IWZ8 SUGP1 SURP and G-patch domain-containing protein 1 1 DVDAS(0.559)PS(0.432)PLS(0.009)VQDLK 92.575 0.017684000000000002 0.0 9365.4 11243.0 8669.7 7823.7 9678.2 10160.0 8687.0 8167.0 7987.0 6589.5 True False 9231.847678595987 11216.967524267855 7956.910732009801 8399.080997098115 9108.947304073297 9725.48048411678 9136.770354182552 8546.46863509933 7087.41995316138 7728.486295043168 1.1945220999508057 1.4513796228715705 1.0295561676952365 1.0867692166944836 1.1786198430494104 1.2583939613575337 1.1822199076735915 1.1058399159717465 0.9170515004609701 1.0 12.915970159551911 -1.52287903418328 0.09793843205339069 0.8666163110504059 2.0592786616746785 0.3228911610737797 0.11716051355578055 170.55861303028541 1.1920316518946292 1.701597167452182 27.31600237478661 0.029999980043298374 1.52287903418328 1.1926623506242726 DVDASPS(ph)PLSVQDLK ddPTM_PC-9_AZD4547_30min_R2 2 DVDASPSPLSVQDLK 15 0 Q8IWZ8 Q8IWZ8 SUGP1 SURP and G-patch domain-containing protein 1 1 DVDAS(0.037)PS(0.94)PLS(0.023)VQDLK;DVDAS(0.002)PS(0.977)PLS(0.021)VQDLK 169.4 2.9247e-05 12071800.0 63376.0 65301.0 71029.0 89652.0 80513.0 81010.0 68999.0 77958.0 71364.0 73329.0 True False 83528.2496973088 86408.27121934548 70087.1090504759 68984.11650959254 69335.15970554216 75944.431893698 75139.77733122533 65911.38239662423 75136.15534750653 70761.77402961055 1.1804148615940022 1.2211151063452366 0.9904656859104136 0.9748782793479126 0.9798391950508276 1.0732409261237394 1.0618696091449429 0.9314546349423539 1.0618184235469492 1.0 16.110682597046996 -5.261832457163646 24.99989230489343 1.0086422433637345 1.2007649981894384 0.7555698150524717 0.04358294511709666 15.45625696014711 983104.4905601492 0.01149204335922026 0.02652906148021859 5.472270323185721e-06 5.261832457163646 0.19212275482570385 DVDASPS(ph)PLSVQDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DVDASPSPLSVQDLK 15 0 Q8IWZ8 Q8IWZ8 SUGP1 SURP and G-patch domain-containing protein 1 1 DVDASPS(0.977)PLS(0.023)VQDLK;DVDAS(0.08)PS(0.903)PLS(0.017)VQDLK;DVDAS(0.367)PS(0.633)PLS(0.001)VQDLK 147.92 3.0126999999999998e-05 10300800.0 45132.0 52985.0 54657.1 63162.0 70473.0 61771.0 64109.0 59236.0 61498.0 42289.5 True False 52771.95620236787 58245.00063433405 55960.33255220602 59623.23791396691 56664.321544663435 58531.620018369336 58036.131411033806 57681.11776572998 62397.291907214414 49956.25158650218 1.056363408511348 1.1659201558283334 1.1201867789321107 1.1935090408199618 1.1342788889303643 1.1716575635587552 1.1617391130825907 1.1546326222225007 1.2490387073811942 1.0 15.608377609488828 -4.757905775648133 24.81870280799879 1.155902898082442 1.0563632548673734 0.1723772711162882 0.060433174179297305 144.15388221311102 1012310.0015239406 0.013626257615720064 0.09703868410596656 1.746200966867705e-05 4.757905775648133 -0.09953964321506859 DVDASPS(ph)PLSVQDLK ddPTM_PC-9_Lapatinib_30min_R1 1 DVDASPSPLSVQDLK 15 0 Q8IWZ8 Q8IWZ8 SUGP1 SURP and G-patch domain-containing protein 1 1 DVDAS(0.025)PS(0.964)PLS(0.011)VQDLK 166.9 1.5783e-20 0.0 38239.0 31882.0 32278.0 32131.0 33787.0 36540.0 36377.0 30086.0 36475.0 26276.0 True False 37693.704847826215 31808.179187824247 29624.227436683203 34494.02092587387 31799.715087797784 34977.26937890027 38260.423065972 31483.905394342884 32366.80140122216 30817.771589430806 1.2231158485434932 1.0321375475030488 0.9612709131390623 1.1192899144500073 1.0318628975335693 1.1349707514509582 1.241505180053113 1.0216152489474786 1.0502641732967677 1.0 14.911474924948267 DVDDDGEEKELMER ddPTM_PC-9_Lapatinib_30min_R1 1 DVDDDGEEKELMER 14 1 Q5STZ8;Q8NE71-2;Q8NE71;A0A0G2JIC2 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 0 104.94 0.0013209 1885300.0 14386.0 16356.0 13376.0 13581.0 12101.0 12586.0 12481.0 12910.0 14303.0 10599.0 False True 14180.853001930704 16318.128686909653 12276.276912853164 14579.792044887907 11389.242971481366 12047.726119398989 13127.205109997987 13509.845730272102 12692.045522732838 12431.02302772024 1.1407631512151875 1.3126939472738053 0.9875516186783658 1.172855364548523 0.9161951470996568 0.9691661010146527 1.0560036033016198 1.0867847079155246 1.0209976680463497 1.0 13.601657409349801 -5.269308443219176 24.996023366328686 1.0296309806630837 1.2267285526725615 0.5234036187058146 0.0764867916261054 407.93519114566857 1295806.5031122377 0.01974062805944747 0.04232945343905929 5.37887630017764e-06 5.269308443219176 0.19709757200947786 DVDDFFEHER ddPTM_PC-9_AZD4547_30min_R2 2 DVDDFFEHER 10 0 Q9UNH7-2;G3V5X9;A0A0A0MRI2;Q9UNH7 Q9UNH7-2 SNX6 Sorting nexin-6;Sorting nexin-6, N-terminally processed 0 ; 99.34299999999999 0.0037014 8230000.0 54171.0 49613.0 75246.0 69691.0 73015.0 79006.0 69145.0 80057.0 70234.0 67008.0 False True 71396.25117320313 65649.43201490621 74248.18887513706 53624.816665216735 62878.12758064104 74065.74233049639 75298.77104838596 67686.03017684602 73946.42585444724 64662.07031564779 1.1041442197053457 1.015269565209382 1.148249484012724 0.8293086875110445 0.9724112957364582 1.145427945145347 1.164496754910802 1.0467655898803854 1.1435827138456576 1.0 15.980632079192572 -6.76155946021914 24.999999978703848 1.107005087354167 1.011165414103544 0.18015453710000828 0.09122835508400375 5.521114940127183 1149254.4649874195 0.03179899400725121 0.029848439531263347 1.7315719411717108e-07 6.76155946021914 -0.09583967325062304 DVDDFFEHER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DVDDFFEHER 10 0 Q9UNH7-2;G3V5X9;A0A0A0MRI2;Q9UNH7 Q9UNH7-2 SNX6 Sorting nexin-6;Sorting nexin-6, N-terminally processed 0 ;;; 144.55 0.00011232 9264500.0 97989.0 112931.0 122319.0 119935.0 131217.0 103758.0 119999.0 92001.0 91713.0 85286.0 False True 114576.60232903126 124142.04334502143 125235.54885739053 113215.43078451625 105505.9707991159 98316.74782448015 108631.8260024748 89586.07123311724 93054.12912105024 100747.6766763955 1.1372629732897432 1.2322075053280814 1.2430614083503961 1.1237522741905757 1.0472298149167665 0.9758711175075176 1.0782563884962173 0.8892122795136045 0.9236354841208184 1.0 16.620387043849206 -6.319682811568059 1.3919590331653242 0.9659439438030568 1.2094753257840267 0.7753684449878534 0.054429068674252984 0.19585464645517384 0.7665511743869339 0.022114748105685877 0.02936574563067418 4.789797891019609e-07 6.319682811568059 0.2435313819809699 DVDDFFEHER ddPTM_PC-9_Lapatinib_30min_R1 3 DVDDFFEHER 10 0 Q9UNH7-2;G3V5X9;A0A0A0MRI2;Q9UNH7 Q9UNH7-2 SNX6 Sorting nexin-6;Sorting nexin-6, N-terminally processed 0 ;; 131.83 0.00014004 8762620.0 71136.0 85090.0 89368.0 71247.6 77907.4 87667.6 75824.0 73552.6 85897.0 66752.1 False True 70121.58759525529 84892.97933291404 82020.50801045616 76487.38617902617 73325.03990384155 83918.26111115704 79749.7957103186 76970.12231296758 76222.37532449023 78290.1115434177 0.8956634013270965 1.0843384644538991 1.047648373383268 0.9769737795891147 0.9365811142468146 1.071888383561928 1.0186445534196409 0.9831397707267527 0.9735887945723419 1.0 16.256542478532268 -7.777223608171428 23.50150111231803 0.9837731777806764 1.008178626556535 0.02082693748315012 0.0553657891486162 509.8970098435904 759175.123521634 0.030089670415321092 0.014550560393133944 1.670230429915693e-08 7.777223608171428 0.024405448775858485 DVDDGSGSPHS(ph)PHQLSSK ddPTM_PC-9_AZD4547_30min_R2 3 DVDDGSGSPHSPHQLSSK 18 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 DVDDGS(0.002)GS(0.004)PHS(0.992)PHQLS(0.001)SK;DVDDGS(0.001)GS(0.012)PHS(0.988)PHQLSSK;DVDDGS(0.026)GS(0.026)PHS(0.947)PHQLS(0.001)SK 89.311 0.00089341 28106900.0 25116.300000000003 19386.2 71493.0 129510.0 103576.0 96268.0 55734.0 98039.0 64892.0 84900.0 True False 33102.76094850609 25652.410032196698 70544.95610730359 99653.47040955396 89196.26025190027 90248.34674166804 60694.21802893553 82889.3252620982 68322.05864035635 81927.67684154882 0.4040485733841576 0.31311042887020235 0.8610637921997979 1.2163590406974127 1.0887195107998626 1.1015611600486575 0.7408267922245667 1.0117377723575542 0.8339313559750237 1.0 16.32206328558953 -5.342343903441957 4.15653845999083 0.9987202464849927 0.35558574274612464 0.7896518405744053 0.12988923369521685 0.09346776819369514 2.978214113526041 0.03638438811969308 0.08299671014413737 4.546279127608551e-06 5.342343903441957 -0.643134503738868 down DVDDGSGSPHS(ph)PHQLSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DVDDGSGSPHSPHQLSSK 18 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 DVDDGS(0.122)GS(0.171)PHS(0.705)PHQLS(0.001)SK;DVDDGS(0.054)GS(0.076)PHS(0.87)PHQLSSK;DVDDGSGS(0.002)PHS(0.998)PHQLSSK 95.87299999999999 0.0025153000000000003 9417600.0 23654.8 33162.3 67554.0 82749.0 88701.0 91211.0 74462.0 79612.0 74652.0 57947.0 True False 27659.09043640371 36454.43398199446 69164.74355997152 78112.84180587776 71320.67579545628 86427.7345922113 67408.42030180481 77522.26935588651 75743.64427229125 68452.3323918004 0.4040635208467618 0.5325521090112799 1.0104074053181051 1.1411275419920468 1.0419027855360479 1.2625973662595622 0.9847497951710316 1.1325000426891598 1.1065166317307873 1.0 16.062812079144475 -5.24555775955998 2.8361150210718233 1.1016215248611296 0.4179526852671162 0.9162937647443402 0.07537931433430746 0.06324825853793482 1.000131074301692 0.019178539520852286 0.06035230412536456 5.681228283000745e-06 5.24555775955998 -0.6836688395940134 down DVDDGSGSPHS(ph)PHQLSSK ddPTM_PC-9_Lapatinib_30min_R1 3 DVDDGSGSPHSPHQLSSK 18 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 DVDDGSGSPHS(0.999)PHQLSSK;DVDDGS(0.079)GS(0.079)PHS(0.842)PHQLSSK;DVDDGS(0.001)GS(0.027)PHS(0.972)PHQLSSK 96.016 0.00048767 28921400.0 123848.0 85335.0 184072.0 117261.0 164543.0 182451.0 132769.0 162085.0 220157.0 118462.0 True False 122081.90480905813 85137.41205046691 168938.31069846792 125884.76511122909 154864.90424398458 174647.9960440539 139643.12917629373 169616.06082038366 195360.6003040126 138937.99885930718 0.8786790209399947 0.6127726953709736 1.2159258956186634 0.9060499369845093 1.114633185416795 1.2570210991804176 1.0050751437531542 1.2208039716488361 1.4060991370822942 1.0 17.084081697720073 -5.398115980897536 0.770929488332887 1.186192076945138 0.6705547087145289 0.4119755138584914 0.16711481181647883 1.2429475823259089 0.995082381894794 0.07171945321889504 0.47820449922766056 3.998379564222329e-06 5.398115980897536 -0.515637368230609 DVDEIEAWISEK ddPTM_PC-9_AZD4547_30min_R2 1 DVDEIEAWISEK 12 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 118.9 0.0025954 1640200.0 6848.2 7997.6 8426.1 15174.0 12377.0 10825.0 8533.5 8836.8 8709.2 8314.8 False True 9025.785148591127 10582.667798407949 8314.364408484063 11675.86873596302 10658.667192571316 10148.11103875177 9292.96496842001 7471.275609462649 9169.55053181581 8023.701382828149 1.124890461141485 1.3189259287560662 1.0362255537423133 1.4551723922516637 1.3283977909973526 1.2647667896103607 1.1581892850983044 0.9311507561151555 1.1428080500901916 1.0 12.970052198995827 -7.529058966842342 4.36437041282197 1.027598628159871 1.258018277290179 0.43279926189838747 0.11763376171503187 0.19075958485028421 9.010484137765761 0.055596298415487765 0.03279157945696996 2.9576108662061374e-08 7.529058966842342 0.23041964913030788 DVDEIEAWISEK ddPTM_PC-9_Lapatinib_30min_R1 1 DVDEIEAWISEK 12 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 134.3 0.00026256 3604800.0 21270.0 17245.0 22361.0 15916.0 22721.0 20500.0 19892.0 17361.0 19032.0 18207.0 False True 20966.685899559707 17205.070262029636 20522.56489595615 17086.515734219556 21384.595451204714 19623.262787834043 20921.910427696494 18167.655439446473 16888.41574415518 21354.055690697474 0.9818596618483805 0.8057050384824428 0.9610616921307578 0.8001531878397695 1.0014301620708306 0.9189478135707297 0.9797628483665874 0.8507824322740198 0.790876262044794 1.0 14.382222480738589 -4.462690157711865 21.371762148670673 0.9007605857326644 2.5498981305813824 0.08435239096746439 0.07995058919468803 400.84468240502997 203951.89763155175 0.01856102114278491 13390.707984246948 3.445956908266532e-05 4.462690157711865 1.649137544848718 DVDELPSLQPS(ph)VGSPSRPSSSR ddPTM_PC-9_AZD4547_30min_R2 1 DVDELPSLQPSVGSPSRPSSSR 22 1 O43815-2;O43815 O43815-2 STRN Striatin 1 DVDELPSLQPS(0.488)VGS(0.42)PS(0.086)RPS(0.002)S(0.002)S(0.002)R 85.087 0.00010849 3130200.0 20903.0 19824.0 28772.0 39840.0 37014.0 32204.0 25981.0 33942.0 29528.0 33653.0 True False 27549.719190590265 26231.72032055108 28390.464480709164 30655.50352186415 31875.24500814697 30190.27878909579 28293.258668133858 28697.043809566967 31088.789797393256 32474.818713175973 0.8483409694728349 0.807755712271555 0.8742301144606647 0.9439776644365477 0.9815372732231531 0.9296519575903506 0.8712368471715122 0.8836706391812357 0.9573198875096302 1.0 14.98703385157112 -5.559449353593081 3.759121412283629 0.931730404596068 0.8292926471287545 0.5725118340206707 0.038530230300964134 0.17135047264930062 5.144132082153316 0.011297438569100472 0.0219316481892107 2.757723032806402e-06 5.559449353593081 -0.10243775746731354 DVDELPSLQPS(ph)VGSPSRPSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DVDELPSLQPSVGSPSRPSSSR 22 1 O43815-2;O43815 O43815-2 STRN Striatin 1 DVDELPSLQPS(0.533)VGS(0.371)PS(0.088)RPS(0.003)S(0.002)S(0.003)R 65.954 0.0013424 22968000.0 14938.0 18845.0 23444.0 17284.0 23845.0 20811.0 22407.0 25152.0 15506.0 13083.0 True False 17466.708361051395 20715.80705773378 24002.99387186512 16315.633515484044 19172.74342276475 19719.634524328292 20284.446747368296 24491.786650746853 15732.745915530048 15454.844335028984 1.1301769194441154 1.3404086517248592 1.5531048615909664 1.0556970462979074 1.2405652886007406 1.2759516755295297 1.3124976420107213 1.5847320179883857 1.0179815192231467 1.0 13.91577150264156 -8.412831279597489 11.041829834681238 1.0001256403606558 1.3085391915480296 0.38068350228453973 0.15445244238123387 0.49532483671316124 45.1053455548744 0.1490750792722585 0.03849784651427402 3.865171071127836e-09 8.412831279597489 0.3084135511873738 DVDELPSLQPSVGS(ph)PSRPSSSR ddPTM_PC-9_AZD4547_30min_R2 2 DVDELPSLQPSVGSPSRPSSSR 22 1 O43815-2;O43815 O43815-2 STRN Striatin 1 DVDELPSLQPS(0.003)VGS(0.95)PS(0.045)RPS(0.001)S(0.001)S(0.001)R;DVDELPSLQPS(0.19)VGS(0.403)PS(0.403)RPS(0.001)S(0.001)S(0.002)R 134.52 1.0384000000000001e-05 70004000.0 44630.0 43163.0 62575.0 78541.0 78973.0 59552.0 47162.0 72522.0 54158.0 69853.0 True False 58821.411638331556 57114.59565153075 61745.21461422135 60434.5858963537 68008.96212320708 55828.204025842504 51359.32663509984 61315.39128977116 57020.68131425167 67407.46773159849 0.8726245565631586 0.8473036827158132 0.9159996168388499 0.8965562411718351 1.0089232604613425 0.828219867984627 0.761923394594813 0.9096231226770806 0.8459104492887244 1.0 16.040620808679762 DVDELPSLQPSVGS(ph)PSRPSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DVDELPSLQPSVGSPSRPSSSR 22 1 O43815-2;O43815 O43815-2 STRN Striatin 1 DVDELPSLQPS(0.087)VGS(0.733)PS(0.174)RPS(0.002)S(0.002)S(0.002)R;DVDELPSLQPS(0.24)VGS(0.406)PS(0.349)RPS(0.002)S(0.002)S(0.002)R;DVDELPSLQPS(0.166)VGS(0.678)PS(0.141)RPS(0.005)S(0.005)S(0.005)R 101.04 4.0376e-05 15969600.0 48689.0 57587.0 54979.0 55889.0 71360.0 65961.0 65507.0 60939.0 58235.0 50231.0 True False 56931.086048415535 63303.85678077561 56289.90786901858 52757.72052458273 57377.52026204625 62501.889042295865 59301.70273039032 59339.41582020763 59086.57670520399 59337.48267162278 0.9594455896195598 1.0668443272375234 0.9486399714752028 0.8891128869848952 0.9669692356107676 1.0533289622039597 0.9993970094513367 1.0000325788775966 0.9957715434642328 1.0 15.856656102892718 -6.600038046395352 24.999352170063464 1.0091847546339403 0.9664799639650168 0.20085493286104128 0.043380831161162696 66.37605758303688 21502.52819409944 0.015513763781464757 0.015513764146128237 2.5116663871796913e-07 6.600038046395352 -0.04270479066892352 DVDELPSLQPSVGS(ph)PSRPSSSR ddPTM_PC-9_Lapatinib_30min_R1 4 DVDELPSLQPSVGSPSRPSSSR 22 1 O43815-2;O43815 O43815-2 STRN Striatin 1 DVDELPSLQPS(0.278)VGS(0.35)PS(0.35)RPS(0.006)S(0.006)S(0.01)R;DVDELPSLQPS(0.015)VGS(0.853)PS(0.128)RPS(0.002)S(0.002)S(0.001)R;DVDELPSLQPS(0.011)VGS(0.493)PS(0.493)RPS(0.001)S(0.001)S(0.001)R;DVDELPSLQPS(0.269)VGS(0.565)PS(0.158)RPS(0.001)S(0.003)S(0.003)R 125.51 8.1542e-07 67469000.0 86011.0 93039.0 97949.0 95670.0 94934.0 95870.0 90277.0 79537.0 100720.0 78936.3 True False 84784.46736751455 92823.57391179894 89896.01131407419 102705.89094576432 89350.16876742519 91769.86358388532 94951.10133124661 83232.57938409387 89375.85297138031 92580.33427899174 0.9157934892740366 1.0026273358667532 0.9710054733996929 1.1093704915372105 0.9651095933415793 0.9912457575205544 1.0256076743589038 0.8990308798548047 0.965387019472681 1.0 16.498418151314844 -10.007759594243685 8.008523511222812 1.000005687491348 0.9852803044048343 0.006835775000965771 0.05534882957784464 0.0 0.0 0.05409091347075971 0.013118973507416913 9.822915446613656e-11 10.007759594243685 -0.014725383086513832 DVDELPSLQPSVGSPS(ph)RPSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DVDELPSLQPSVGSPSRPSSSR 22 1 O43815-2;O43815 O43815-2 STRN Striatin 1 DVDELPS(0.001)LQPS(0.212)VGS(0.212)PS(0.495)RPS(0.027)S(0.027)S(0.027)R;DVDELPSLQPS(0.025)VGS(0.072)PS(0.896)RPS(0.002)S(0.003)S(0.002)R 99.40899999999999 5.1173999999999995e-05 26981200.0 30362.0 29321.7 29727.0 31769.0 41681.0 34462.0 38219.0 39916.0 33274.0 28759.0 True False 35501.686923165245 32232.564595635584 30435.804420275304 29989.085926487685 33513.90725956207 32654.75205311625 34598.61963840179 38868.24729449791 33760.569301776515 33972.77904388126 1.0450039096686543 0.9487762115075158 0.8958879808143635 0.8827386740352328 0.9864929570899547 0.9612034391103959 1.018421825123937 1.144099728912179 0.9937535359756515 1.0 15.052091618044349 -7.321988977877608 3.1560806475520224 1.055703631198441 0.9475546142448438 0.3460051682334304 0.0574923633120352 0.2622014258862263 5.18592397113334 0.026604265708826035 0.017421432853612775 4.764430784793932e-08 7.321988977877608 -0.10814901695359713 DVDETGITVAS(ph)LER ddPTM_PC-9_AZD4547_30min_R2 2 DVDETGITVASLER 14 0 Q8WU90;H7C466 Q8WU90 ZC3H15 Zinc finger CCCH domain-containing protein 15 1 DVDETGITVAS(1)LER;DVDETGITVAS(1)LER 170.74 0.00025346 4355600.0 11070.2 11269.0 12775.3 19375.8 16570.6 13209.8 12271.1 14322.4 12203.2 11202.1 True False 14590.293325535691 14911.483872694213 12605.891174767261 14909.008663125898 14270.058219376457 12383.789117755487 13363.204127729407 12109.20217601031 12848.236238673444 10809.917888653867 1.3497136126121478 1.3794261923437334 1.166141251451915 1.3791972165463398 1.3200894184732308 1.1455951141639624 1.2361984859991841 1.1201937240171065 1.1885600215482677 1.0 13.400067944057556 -7.7812758072249855 0.1715665731556416 0.8933323845559347 1.476640825722632 0.6639245230125943 0.06979034619915779 2.2667180631123265 0.3896763749567108 0.5098375362915213 0.5748778914336375 1.6547187681196396e-08 7.7812758072249855 0.5833084411666973 DVDETGITVAS(ph)LER ddPTM_PC-9_Lapatinib_30min_R1 2 DVDETGITVASLER 14 0 Q8WU90;H7C466 Q8WU90 ZC3H15 Zinc finger CCCH domain-containing protein 15 1 DVDETGITVAS(1)LER;DVDETGITVAS(1)LER 227.47 1.4694999999999998e-20 4293200.0 16251.099999999999 13514.3 13819.4 13424.3 16416.1 13816.7 15993.2 13547.7 13804.900000000001 10880.0 True False 16019.356333913254 13483.008468666112 12683.222276426659 14411.567804152024 15450.537273294383 13225.791949300812 16821.249640671405 14177.175600310406 12250.046789958367 12760.593503311286 1.2553770582658512 1.05661295966895 0.9939367062461045 1.1293806828351927 1.210800835343989 1.0364558627989215 1.3182184383748614 1.1110122422308593 0.9599903630485185 1.0 13.639407810875696 -10.446016150899254 5.103997262055804 0.9999996180641532 1.1197580345287357 0.09719354868634245 0.10886698081003539 75810221.47846423 18.625458330598757 340.2180031104745 0.0262284558307237 3.580831201663658e-11 10.446016150899254 0.11975841646458252 DVDFELIK ddPTM_PC-9_Lapatinib_30min_R1 2 DVDFELIK 8 0 E7ENZ3;B7ZAR1;E9PCA1;P48643-2;P48643 E7ENZ3 CCT5 T-complex protein 1 subunit epsilon 0 ; 103.56 0.018125 9157400.0 61734.0 62821.0 70646.0 58983.0 67043.0 54635.0 61166.0 61441.0 58925.0 67401.0 False True 60853.661839370885 62675.541834210766 64837.7585814462 63320.806581519966 63099.66255160935 52298.388410405525 64332.87619246347 64295.77316139802 52288.24599224169 79051.173043813 0.7698008707048989 0.7928477139671758 0.8201998286035652 0.8010103347413364 0.7982128553188862 0.6615763738435593 0.8138130493877412 0.8133436947958127 0.6614480719123759 1.0 16.270499250506724 -11.173179865136852 6.119523674672339 1.00164114679161 0.7734635950142699 0.5953253017328977 0.056771042271737064 0.0012680260260262016 7.246092262980144e-05 0.0548336212142218 0.013210517582148007 6.71150835030354e-12 11.173179865136852 -0.22817755177734012 DVDIIDHHDNTYTVK ddPTM_PC-9_AZD4547_30min_R2 2 DVDIIDHHDNTYTVK 15 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 99.834 0.0008349999999999999 30291000.0 138720.0 130536.0 186719.0 231290.0 203540.0 174189.0 149227.0 195686.0 166716.0 189089.0 False True 182830.07444475376 172729.20922939118 184242.98405997283 177969.6638948787 175281.98435614145 163296.9342936843 162507.9139089954 165447.22511693236 175528.26740254034 182469.0516642127 1.0019785425377528 0.946621948511328 1.0097218261375338 0.975341638879047 0.9606121298788948 0.8949294842294148 0.8906053515751776 0.9067138980992534 0.9619618549098119 1.0 17.477292265570398 -6.56168681380537 5.0220431275213615 0.9225294987280594 0.9812549150948212 0.32391164751924484 0.03476540475358799 0.1999823346190809 12.093381830145985 0.011324488242438379 0.01152532081363346 2.743551937902977e-07 6.56168681380537 0.05872541636676176 DVDIIDHHDNTYTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DVDIIDHHDNTYTVK 15 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 51.93899999999999 0.037485000000000004 22624000.0 175769.0 163990.0 162933.0 200967.0 221900.0 181146.0 195969.0 191239.0 169562.0 146471.0 False True 205523.22010400638 180269.84342784603 166817.9406468437 189707.47053380476 178420.28792247816 171646.38487069198 177405.39762730448 186219.17888446982 172041.52347021175 173025.03283620198 1.1878236156647317 1.0418714591344855 0.9641260453033154 1.0964163244135638 1.0311819336071661 0.99203208956004 1.025316364454901 1.0762557060790063 0.9943157972585314 1.0 17.40062125296948 -4.768799326471681 4.827649871830768 1.0257163727992507 1.1981763237844973 0.6306061973718309 0.03765381643879776 0.1116827779737319 6.434779800736318 0.009187099605754612 0.0652476718590531 1.70294520289874e-05 4.768799326471681 0.1724599509852467 DVDIIDHHDNTYTVK ddPTM_PC-9_Lapatinib_30min_R1 2 DVDIIDHHDNTYTVK 15 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 93.228 0.0014060000000000001 33307000.0 195963.0 204738.0 226396.0 179700.0 214216.0 193477.0 204695.0 174497.0 209408.0 169173.0 False True 193168.53168478742 204263.94174006552 207782.59479383292 192915.73746162673 201616.23604486024 185202.43972691539 215293.1055196726 182604.76765261788 185822.26587600078 198414.32764114704 0.9735614054754796 1.0294818129742027 1.0472156787468965 0.9722873330525551 1.0161374858447934 0.9334126316818877 1.0850683419851241 0.9203204719312287 0.9365365298219778 1.0 17.598156681968554 -7.8080507298327895 24.999998514943822 0.9463213500370842 1.0065400355189853 0.24613083499441946 0.044386180552777425 163.14580058566636 87501.02767000425 0.023009779757354895 0.01105359387234993 1.5557838902529217e-08 7.8080507298327895 0.060218685481901124 DVDLEFLAK ddPTM_PC-9_AZD4547_30min_R2 1 DVDLEFLAK 9 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 117.89 0.0084355 1888600.0 25157.0 19654.0 32055.0 39263.0 35415.0 31555.0 26533.0 27316.0 27095.0 33060.0 False True 33156.40270189348 26006.77114508226 31629.929755635058 30211.521957303015 30498.238557397857 29581.860861691635 28894.385598768178 23094.939859234317 28527.186384461183 31902.57946268083 1.0393016257722782 0.8151933662763727 0.9914536783032006 0.9469930791221447 0.955980333598863 0.9272560827345031 0.9057068765417043 0.7239207690478583 0.8941968600950235 1.0 14.961385456441441 -7.531572956251586 24.979447407278204 0.8483980543586213 0.9404632580800417 0.11548528577438677 0.08312323047078342 308.3961060886536 886042.9858204918 0.036509144001464176 0.021120821084824187 2.940539676941402e-08 7.531572956251586 0.09206520372142046 DVDLEFLAK ddPTM_PC-9_Lapatinib_30min_R1 2 DVDLEFLAK 9 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 ; 135.79 0.004784399999999999 15299600.0 128087.0 105561.0 119926.0 110698.0 110967.0 99189.0 108413.0 102926.0 102202.0 114825.0 False True 126260.45589172073 105316.57999014834 110066.1472077472 118839.10019770269 104440.13922951603 94946.91769085232 114026.09467111687 107708.31770983637 90690.93452522848 134672.34825530465 0.937538088014645 0.782020818338259 0.8172883938957511 0.8824313360335402 0.7755128694386764 0.7050216241188356 0.8466927037980527 0.7997804976686728 0.6734191220405651 1.0 17.03909413273366 -4.756170782002118 24.891168079225004 0.8022884194509632 0.9375383119347444 0.16140793085004046 0.08655149983243746 272.7685189513945 1288529.422548485 0.020376536031735476 0.16868817691264196 1.7531909413017695e-05 4.756170782002118 0.13524989248378116 DVDNALR ddPTM_PC-9_Lapatinib_30min_R1 1 DVDNALR 7 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 98.99700000000001 0.017412 0.0 24948.0 29169.0 31440.0 28008.0 31106.0 32426.0 23846.0 25317.0 30859.0 23217.0 False True 24592.236945097124 29101.46097263803 28855.12456190962 30067.801751949075 29276.40623674898 31039.215568697895 25080.62920062589 26493.320244252427 27383.33446032391 27230.027515292084 0.9031293461340204 1.0687268294640895 1.0596803306829161 1.1042148868583892 1.0751515480587623 1.1398892473122406 0.9210651434906146 0.9729450412554328 1.005630069413104 1.0 14.732910819740757 -7.272081962328996 24.982473238095608 0.9726554868876113 1.0618250089480954 0.30599833103281293 0.061483145616293644 900.1458626317602 2113001.8468568176 0.025931550019923606 0.017689889847676114 5.344634831308363e-08 7.272081962328996 0.08916952206048412 DVDVS(ph)EDSPPPLPER ddPTM_PC-9_AZD4547_30min_R2 1 DVDVSEDSPPPLPER 15 0 Q05209-2;Q05209-3;Q05209 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 DVDVS(0.514)EDS(0.486)PPPLPER 155.06 0.00018618 11848000.0 10821.0 11359.0 12313.0 9104.6 11679.0 13870.0 13109.0 15191.0 11815.0 10656.0 True False 14261.852909217687 15030.574612648288 12149.721574828716 7005.675134667785 10057.572444214302 13002.706707389098 14275.675604502014 12843.580004452644 12439.516779199443 10282.936683433963 1.386943569553807 1.4617005895662931 1.1815420000010488 0.6812912838366574 0.9780836694654818 1.264493510724105 1.388287805710254 1.2490186801542729 1.2097241441970343 1.0 13.327964719333027 DVDVS(ph)EDSPPPLPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DVDVSEDSPPPLPER 15 0 Q05209-2;Q05209-3;Q05209 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 DVDVS(0.54)EDS(0.46)PPPLPER;DVDVS(0.999)EDS(0.001)PPPLPER 207.08 6.021699999999999e-13 43959000.0 33982.0 50245.0 50071.0 42754.0 51117.0 34984.0 41930.0 30492.0 34793.0 30824.0 True False 39734.48142490619 55232.99154236321 51264.882535324934 40358.631990338166 41100.990796454804 33149.37745418775 37958.08685308846 29691.617308944536 35301.781803110855 36412.14719735027 1.0912424694305776 1.5168836718967933 1.40790605556641 1.1083837426998835 1.1287714117404684 0.9103933715999052 1.0424567012584935 0.8154316510921171 0.9695056326060272 1.0 15.152132197498348 -6.209647503461955 1.4726861173111243 0.9426833614343135 1.3516113790689706 0.6246291426945687 0.12508699339458754 0.24375710268627432 1.058269350647921 0.04531506911862392 0.06539014446024842 6.170956663688803e-07 6.209647503461955 0.408928017634657 DVDVS(ph)EDSPPPLPER ddPTM_PC-9_Lapatinib_30min_R1 1 DVDVSEDSPPPLPER 15 0 Q05209-2;Q05209-3;Q05209 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 DVDVS(0.996)EDS(0.004)PPPLPER 201.72 2.0305e-10 9541200.0 11732.0 19799.0 16433.0 17369.0 18309.0 19103.0 21008.0 21520.0 20117.0 19099.0 True False 11564.699528614694 19753.156631946942 15081.942173214411 18646.37420128546 17232.10061687896 18286.00922126799 22095.69144706654 22519.897762622448 17851.21161859866 22400.23670218218 0.5162757734380586 0.8818280313092689 0.6732938751377195 0.8324186234812855 0.7692820770594915 0.8163310711572349 0.9864043733481632 1.0053419551780276 0.7969206690061286 1.0 14.4512263567993 -3.3728894675075676 0.22908695916954175 0.9967058815808546 6.694877608437555e-17 0.5338713182223318 0.10003857908483323 18.09790813576572 0.488239568746711 0.15313012378899793 5.684077193730024 0.00042375080134169745 3.3728894675075676 -0.9967058815808545 DVDVSEDS(ph)PPPLPER ddPTM_PC-9_AZD4547_30min_R2 4 DVDVSEDSPPPLPER 15 0 Q05209-2;Q05209-3;Q05209 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 DVDVS(0.139)EDS(0.861)PPPLPER;DVDVS(0.002)EDS(0.998)PPPLPER;DVDVS(0.141)EDS(0.859)PPPLPER;DVDVS(0.034)EDS(0.966)PPPLPER 120.54 7.9859e-05 69372400.0 55947.8 71509.90000000001 77466.0 56006.3 68416.4 78648.1 86764.0 103183.0 84562.6 67585.2 True False 73738.03661346718 94624.07672268832 76438.75022461469 43094.91282370933 58917.96381302706 73730.22187407425 94485.82791586041 87238.43825945882 89032.40639803048 65219.06271933377 1.1306209187763752 1.4508653264444664 1.1720307995465091 0.6607717287990728 0.9033856261715519 1.1305010958432158 1.4487455657324357 1.3376217722552084 1.3651285787588816 1.0 15.993006087426911 -7.069102865663456 6.9409404293474 1.3140229264295515 1.0636705812587202 0.18828428096383143 0.217755194571405 0.44339887990582627 37.94521199141908 0.09154178750221292 0.07113690544889997 8.528980752603796e-08 7.069102865663456 -0.2503523451708314 DVDVSEDS(ph)PPPLPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DVDVSEDSPPPLPER 15 0 Q05209-2;Q05209-3;Q05209 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 DVDVS(0.041)EDS(0.959)PPPLPER;DVDVS(0.008)EDS(0.992)PPPLPER 188.0 2.8484e-07 43326000.0 24586.6 42592.0 46701.0 36579.0 43596.0 32674.0 34034.0 24430.9 29434.2 26197.6 True False 28748.62577251482 46820.25227927817 47814.528954528774 34529.59722071805 35053.67675650458 30960.517920710365 30810.053135177983 23789.61476167826 29864.619490964436 30947.017499912505 0.9289627271059675 1.512916463740344 1.545044815858716 1.115764943126286 1.132699677977165 1.0004362430336913 0.9955742305462907 0.7687207583653423 0.9650241575314608 1.0 14.917512756826769 -6.474574434324412 1.3589073801233247 0.918423074781828 1.3317054171462501 0.45035535820334627 0.17509716124624508 0.36377238342495816 1.3802800739911103 0.07407816488774688 0.08621304045383646 3.3529383305766e-07 6.474574434324412 0.4132823423644221 DVDVSEDS(ph)PPPLPER ddPTM_PC-9_Lapatinib_30min_R1 3 DVDVSEDSPPPLPER 15 0 Q05209-2;Q05209-3;Q05209 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 DVDVS(0.009)EDS(0.991)PPPLPER;DVDVS(0.093)EDS(0.907)PPPLPER;DVDVS(0.028)EDS(0.972)PPPLPER 172.57 2.1878000000000003e-05 79618000.0 26529.6 55644.0 46423.0 42460.0 50766.0 48129.0 49234.0 50024.1 49250.0 43389.3 True False 26151.283039067217 55515.15973675714 42606.28013796217 45582.650042407775 47780.04368979613 46070.63486417876 51783.09561618783 52348.40230795547 43702.94637450828 50889.08269239191 0.5138878843060168 1.0909050979033827 0.8372381242456931 0.8957255197139274 0.9389055797804626 0.9053147045833169 1.0175678726456898 1.0286764771215209 0.8587882520633846 1.0 15.635068565616681 -4.749584817776051 24.999442063944763 0.9482122817708307 0.5138869109699928 0.7446862908775504 0.07702048953468836 272.12738424504124 573839.1383147528 0.01873314387504529 0.303228024908817 1.7799802445024108e-05 4.749584817776051 -0.4343253708008379 DVEDEETWIR ddPTM_PC-9_AZD4547_30min_R2 2 DVEDEETWIR 10 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 ; 176.38 0.0057097 11851700.0 42733.0 40801.0 53962.0 70460.0 65724.0 58294.0 46894.0 53675.0 44896.0 51704.0 False True 56321.20509838271 53989.125342958214 53246.42862185553 54216.535596148264 56599.35707882021 54648.86696471088 51067.47515428465 45380.76207879638 47269.11090299941 49893.85869747277 1.1288203913006931 1.0820795735666937 1.0671940397456685 1.0866374542182773 1.1343952653974043 1.0953024759233336 1.0235222628084952 0.9095460496242399 0.947393369384631 1.0 15.606574628539704 -7.490925053183961 3.250537341891144 0.9469755425913632 1.0974642208970717 0.840612022243272 0.02863598479356706 0.0911766773265187 1.9642509830254782 0.014286213889153776 0.008405366793004116 3.2290513156086204e-08 7.490925053183961 0.15048867830570856 DVEDEETWIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DVEDEETWIR 10 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 ; 170.5 0.0005225 7249700.0 25143.0 23309.0 25455.0 27677.0 31261.0 24272.6 24576.0 24077.0 22045.7 19963.0 False True 29399.21330311389 25622.96347618555 26061.94373862509 26126.34742004466 25135.631458966174 22999.702126529777 22247.983365168173 23445.004261690206 22368.07665613317 23582.13387297896 1.2466731578010544 1.0865413458425417 1.10515629666947 1.1078873337234731 1.0658760396474236 0.9753019913470787 0.9434253696040843 0.9941850210830208 0.948517923637229 1.0 14.525406648701615 -5.492621098135614 0.4927605039697647 0.9574332501945159 1.267620934702478 0.8014910945565029 0.039711587836771325 1.1003163879365565 0.3390075112520799 0.03002636431964679 0.18392003924327952 3.2164655323755866e-06 5.492621098135614 0.3101876845079622 DVEDEETWIR ddPTM_PC-9_Lapatinib_30min_R1 2 DVEDEETWIR 10 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 ; 185.81 0.0022892 13455800.0 28308.0 25269.4 32370.0 27537.0 28392.0 27046.0 27104.0 22371.5 32173.0 26659.0 False True 27904.32272894858 25210.890256847324 29708.66355181346 29562.162840739125 26722.038380819693 25889.305627305355 28507.312499109463 23410.961561176027 28549.337943290473 31266.9726291154 0.8924536142320487 0.8063105614955274 0.9501611781931564 0.9454757002349252 0.8546410520069498 0.8280080689103099 0.9117388126205677 0.7487441089635919 0.9130828968297909 1.0 14.93235191910672 DVEDEILWVGER ddPTM_PC-9_AZD4547_30min_R2 2 DVEDEILWVGER 12 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 ; 199.03 3.4716e-05 4668400.0 14525.4 13380.8 18448.5 21190.6 18856.3 16056.9 17489.7 17687.9 12243.5 17513.4 False True 19144.17505291107 17705.881924194397 18203.860835964228 16305.434561506392 16238.428228430368 15052.859504677437 19046.249417961626 14954.641482506613 12890.66641439935 16900.26119666409 1.1327739157481127 1.0476691287877447 1.0771348811790822 0.9648037016566874 0.9608388911548681 0.8906879798786004 1.1269795890326906 0.884876352411552 0.7627495376783769 1.0 14.044757923348033 -4.79970631871665 0.4389099772800274 0.9142525209647199 1.27616447871353 0.36444298897003513 0.08875399048795513 6.03670263300629 0.9192140366738248 0.0687160118181226 1.148680881430689 1.5859653011282e-05 4.79970631871665 0.36191195774881013 DVEDEILWVGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DVEDEILWVGER 12 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 ; 169.82 0.004399800000000001 3349300.0 9203.7 11252.0 7831.4 11498.6 12495.8 13328.599999999999 14285.3 13691.8 10194.099999999999 9151.3 False True 10761.704628638954 12369.02419812261 8018.130276749892 10854.370720964178 10047.337691850847 12629.6247523407 12932.092967384307 13332.404757661252 10343.169427157542 10810.358248349052 0.995499351770555 1.1441826361315635 0.7417081000044021 1.0040713241507837 0.929417643803365 1.168289196546237 1.1962686777155869 1.2332990684834486 0.9567832248979483 1.0 13.400126713403933 -6.760646149128631 24.999802623831904 1.1308430273676997 0.9630332778090587 0.2610886422770453 0.12217397947185038 27.025349893261144 851752.6743906176 0.04138278853875772 0.03909191759926425 1.735217227908724e-07 6.760646149128631 -0.16780974955864103 DVEDEILWVGER ddPTM_PC-9_Lapatinib_30min_R1 1 DVEDEILWVGER 12 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 193.3 8.416e-05 3413000.0 5084.8 4310.2 4695.0 2831.2 3096.8 3875.0 4921.7 4890.0 4595.8 3627.9 False True 5012.28981956188 4300.219996717898 4308.995223224104 3039.415892606333 2914.6523125430563 3709.2752830661902 5176.52154393695 5117.207251822667 4078.1726080805115 4254.977681127114 1.1779826347371485 1.010632797391971 1.0126951411135678 0.7143200553289889 0.6849982610886423 0.8717496450142669 1.2165801872233852 1.202640209963958 0.9584474734542513 1.0 12.054935849144023 -7.248173650414829 24.602428215209763 1.1113036528457398 0.9018082568839778 0.24641154535631582 0.15448363553449024 891.9691425555746 1654234.941875854 0.06537585392828069 0.050324795307169906 5.647111328225212e-08 7.248173650414829 -0.20949539596176203 DVEDESTGLEK ddPTM_PC-9_AZD4547_30min_R2 1 DVEDESTGLEK 11 0 P36952 P36952 SERPINB5 Serpin B5 0 95.48299999999999 0.023 0.0 4854.6 3954.2 6782.7 7227.7 7950.8 6814.5 6080.8 7903.9 4870.2 6873.9 False True 6398.26181804715 5232.317821404512 6692.756966262548 5561.465431851846 6846.968660797935 6388.388237743549 6621.979419929504 6682.533868553301 5127.62882928964 6633.246853252321 0.9645746584736318 0.7888019151343773 1.0089714907837404 0.8384228048327533 1.0322197880274613 0.9630861596250235 0.9983013698160061 1.0074303001820013 0.7730194492574225 1.0 12.695499500773503 -6.2581526605205 24.997166650786095 0.9645494503422007 0.9000061476261635 0.10628861845863125 0.08814833572154221 679.5438023003509 5168274.274867994 0.02539234296996658 0.03146343844731572 5.518834105246602e-07 6.2581526605205 -0.06454330271603725 DVEDMELS(ph)DVEDDGSK ddPTM_PC-9_AZD4547_30min_R2 2 DVEDMELSDVEDDGSK 16 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 DVEDMELS(1)DVEDDGSK;DVEDMELS(1)DVEDDGSK 127.18 2.2465e-05 5527900.0 57636.0 82951.0 60594.0 40976.0 44326.0 84053.0 81948.0 75762.0 80351.0 58490.0 True False 75963.04909672594 109763.28855478369 59790.48396858375 31529.61627288919 38172.10002245425 78797.15262265138 89241.21324568847 64054.723737564396 84598.18982018242 56442.28290297043 1.3458535904246385 1.9446996632555962 1.0593207945073588 0.5586169561406925 0.6763032616536022 1.3960660088485624 1.5811056650402053 1.134871242676 1.4988442258016854 1.0 15.784488720889785 -5.279231694346741 24.607705415587866 1.1093695272443593 1.6452766308472184 0.28404229294799177 0.33789354766124985 804.6638568392711 1112891.727182932 0.09739542523027743 0.2034629834231506 5.257367131536776e-06 5.279231694346741 0.5359071036028591 DVEDMELS(ph)DVEDDGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DVEDMELSDVEDDGSK 16 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 DVEDMELS(1)DVEDDGSK;DVEDMELS(1)DVEDDGSK;DVEDMELS(1)DVEDDGSK 119.54 0.0011459 0.0 53825.0 98182.0 59060.0 53931.0 61618.0 37755.1 63077.0 33973.8 34377.1 48294.0 True False 62936.50940779165 107928.86009776697 60468.21438629728 50909.42091666111 49544.395228514084 35775.15609194501 57101.88992206677 33082.0237482166 34879.80005241635 57049.319904906355 1.103194735935476 1.8918518271150306 1.0599287508964133 0.8923755971415673 0.868448481263195 0.6270917190875799 1.000921483678474 0.5798846297091699 0.6113972981721141 1.0 15.799922067541631 -5.5240706775270745 3.612391325975163 0.7872255467872243 1.5031138409380167 0.5888865690146615 0.23044950002697187 0.1372474128301418 3.8522396214275423 0.06035531929128971 0.12317040479223054 2.9917777120307413e-06 5.5240706775270745 0.7158882941507924 DVEDMELS(ph)DVEDDGSK ddPTM_PC-9_Lapatinib_30min_R1 1 DVEDMELSDVEDDGSK 16 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 DVEDMELS(1)DVEDDGSK 122.96 4.3542e-05 2651100.0 20237.0 43628.0 31939.0 29942.0 41790.0 40736.0 45275.0 42587.0 38045.0 37191.0 True False 19948.416668988717 43526.98204649631 29313.09870810534 32144.03456358394 39331.99436230116 38993.81624025401 47619.11796772364 44565.747491487055 33759.971468389216 43619.41479610749 0.4573288468502992 0.9978809264167517 0.6720195317870514 0.7369203533297382 0.901708437542153 0.893955510923859 1.0916954798754677 1.0216952175952625 0.7739666299099888 1.0 15.412682794268667 -6.432269464141732 2.006150663317219 0.9686481440430523 0.7293677655200598 0.379797877634924 0.14544446035247052 0.3724819204913587 2.9735236430405183 0.050875886363117934 0.05862461425804613 3.6959878583839693e-07 6.432269464141732 -0.23928037852299255 DVEDMFSR ddPTM_PC-9_Lapatinib_30min_R1 1 DVEDMFSR 8 0 Q15717;Q15717-2;M0QZR9;M0R055 Q15717 ELAVL1 ELAV-like protein 1 0 95.815 0.029077 1912000.0 24233.0 18431.0 21010.0 19659.0 19968.0 20869.0 18328.0 16496.0 19444.0 17094.0 False True 23887.432976212072 18388.324151897275 19282.63890094533 21104.788440501532 18793.521498598464 19976.481518015058 19276.934160407258 17262.464381608737 17254.01196560283 20048.675123676745 1.1914718967141074 0.9171840053501262 0.9617911798158296 1.0526774617429735 0.9373946848190486 0.9963990834697886 0.9615066353008987 0.8610276876212336 0.8606060928797473 1.0 14.291219281783 -4.7565864193073155 24.920327354227414 0.9505174064164106 1.1914722800322979 0.6170087829129021 0.05710865319793467 104.2425844136393 535228.2561760949 0.01521246138471504 0.1217063675488028 1.751513869622714e-05 4.7565864193073155 0.2409548736158873 DVES(ph)PSWR ddPTM_PC-9_AZD4547_30min_R2 1 DVESPSWR 8 0 F5H6E2;O00159-2;O00159-3;O00159 F5H6E2 MYO1C Unconventional myosin-Ic 1 DVES(0.887)PS(0.113)WR 98.044 0.0056271 27999000.0 14969.0 15278.0 22281.0 23289.0 23122.0 31237.0 15772.0 20753.0 22711.0 19929.0 True False 19728.83062545787 20216.314722426323 21985.53938185323 17920.08086146322 19911.909414772086 29283.74545196203 17175.67744558744 17546.100706497647 23911.457094574584 19231.291775915506 1.0258713171917793 1.051219801456313 1.14321698396709 0.9318188850894356 1.035391155559761 1.5227133878045473 0.8931109592491111 0.9123724454366439 1.2433619838538525 1.0 14.231168052061635 -5.011327853494043 21.4602024384442 1.0845266955998554 1.0322081803771168 0.011638652490496781 0.17885098290636495 579.8144691077669 1098564.9398461743 0.04572996012235965 0.140131679418907 9.742538854846253e-06 5.011327853494043 -0.05231851522273856 DVES(ph)PSWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DVESPSWR 8 0 F5H6E2;O00159-2;O00159-3;O00159 F5H6E2 MYO1C Unconventional myosin-Ic 1 DVES(0.95)PS(0.05)WR;DVES(0.938)PS(0.062)WR 100.02 0.013028 0.0 43201.0 48452.0 46044.0 58460.0 58713.0 54293.0 52524.0 42628.0 47084.0 46844.0 True False 50514.076041356355 53261.994351887355 47141.8635828424 55184.675729877206 47208.609124797054 51445.77950263597 47548.546479170465 41509.06016809945 47772.51442582334 55336.44638310005 0.9128536316127365 0.9625120121221546 0.8519134614549391 0.9972573111729633 0.853119638329626 0.9296906987209012 0.8592627388825598 0.7501215361884256 0.863310124670623 1.0 15.755942378934755 -7.332643841134077 5.5173623709963575 0.8461649082273598 0.9175406860975375 0.07514808939111273 0.07090024090274819 0.3818633579798762 21.64759757493109 0.028541487333058863 0.01910026138277683 4.6489637398660584e-08 7.332643841134077 0.07137577787017768 DVES(ph)PSWR ddPTM_PC-9_Lapatinib_30min_R1 2 DVESPSWR 8 0 F5H6E2;O00159-2;O00159-3;O00159 F5H6E2 MYO1C Unconventional myosin-Ic 1 DVES(0.872)PS(0.128)WR;DVES(0.967)PS(0.033)WR 128.6 0.0037134 45718000.0 37874.0 34067.0 49496.0 35577.0 49739.0 40097.0 40257.0 29814.0 52523.0 32494.0 True False 37333.90981475903 33988.11995457025 45426.62994008523 38193.4512613929 46813.44981063643 38382.144780672286 42341.3104809862 31199.26728135806 46607.30664829032 38110.54460446659 0.9796215247573098 0.8918298152734037 1.1919701072642555 1.002175425667273 1.2283595077554956 1.00712664117043 1.1110129996941518 0.8186518352115462 1.2229504230917736 1.0 15.217902604140079 -5.237012723920478 24.70369814526244 1.0683595578889564 0.9357256544951904 0.17035438912753298 0.1206680157165701 1173.1387801351293 1186439.2507474686 0.028944888192366805 0.07649030776805783 5.794117206259822e-06 5.237012723920478 -0.13263390339376602 DVESPS(ph)WR ddPTM_PC-9_AZD4547_30min_R2 1 DVESPSWR 8 0 F5H6E2;O00159-2;O00159-3;O00159 F5H6E2 MYO1C Unconventional myosin-Ic 1 DVES(0.073)PS(0.927)WR 94.69200000000001 0.006655599999999999 24938000.0 16463.0 12578.0 26150.0 30588.0 22775.0 20496.0 16560.0 25753.0 15803.0 21080.0 True False 21697.891548327403 16643.592523804036 25803.23391389352 23536.409179889062 19613.08437511608 19214.381879931294 18033.807919029176 21773.465595067406 16638.31431753608 20341.995616252643 1.0666550105335506 0.8181887774327464 1.268471117616283 1.157035407139906 0.9641671714571511 0.9445672018815883 0.8865309116781396 1.0703701842149185 0.8179293040571971 1.0 14.312173598786343 -6.414288269713431 7.178584019738884 0.9457457375569392 1.0723917940358727 0.21606733057003524 0.1219041702883097 0.4560497898128454 26.67279365260998 0.03883459701386339 0.043992332405839274 3.852225753127931e-07 6.414288269713431 0.12664605647893346 DVESPS(ph)WR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DVESPSWR 8 0 F5H6E2;O00159-2;O00159-3;O00159 F5H6E2 MYO1C Unconventional myosin-Ic 1 DVES(0.044)PS(0.956)WR 120.27 0.003423 18379000.0 21466.0 25919.0 35018.0 32920.0 30420.0 28278.0 26733.0 22471.0 24650.0 15282.0 True False 25099.769827174274 28492.06702729649 35852.96192650453 31075.599128080008 24459.419371797165 26795.05189942608 24200.65670984054 21881.16005999256 25010.4596167816 18052.50562775456 1.3903759591458043 1.5782887769048404 1.9860379864046642 1.721400883005586 1.3549044036409212 1.4842843676076976 1.3405705118647684 1.2120843782677841 1.385428711808827 1.0 14.139911471834148 -7.481611908612007 0.5692157444799741 1.0798260325875257 1.6783930380242702 0.5470335093479255 0.1737217110659441 0.6745047350321868 0.45437899523886877 0.17726935047808098 0.12154222872502068 3.29904387491069e-08 7.481611908612007 0.5985670054367445 DVESVQT(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 1 DVESVQTPSK 10 0 P46013 P46013 MKI67 Antigen KI-67 1 DVES(0.042)VQT(0.956)PS(0.002)K 95.273 0.014622 18002000.0 39563.0 58190.0 55950.0 76754.0 86815.0 75134.0 64846.0 82508.0 65777.0 66062.0 True False 52143.211038478796 76998.77953252963 55208.06644291942 59059.55113747892 74762.2357859805 70435.85910259347 70617.16837665242 69758.28444522258 69253.83793359308 63749.18948770793 0.8179431214342421 1.207839349037943 0.8660198958853367 0.9264361102013184 1.1727558638278233 1.104890268701767 1.1077343719055246 1.0942615114922098 1.0863485244302056 1.0 15.960119379097451 -6.252755304843858 24.864132296943744 1.1002428894240943 0.9663267598942192 0.30001826546043964 0.1037362492571843 783.5211088967775 2243366.5140011767 0.029644674572773918 0.037651292318946594 5.587849430522607e-07 6.252755304843858 -0.13391612952987508 DVESYIHR ddPTM_PC-9_AZD4547_30min_R2 2 DVESYIHR 8 0 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 0 ; 145.63 0.0011652000000000001 12384700.0 88603.0 106381.0 131480.0 139769.0 113263.0 130749.0 113358.0 156110.0 113445.0 124962.0 False True 116776.91094311171 140766.57785616128 129736.48929249412 107547.4164595238 97538.38751169143 122573.24436080855 123446.64239645608 131986.7865509249 119441.47109744235 120587.11841547239 0.9684028648961248 1.1673434086977874 1.0758735343977486 0.8918648846801245 0.8088624124479982 1.0164704652655612 1.0237133453270808 1.0945347088913424 0.9904994220520071 1.0 16.87971627561594 -5.652122211912559 10.366214233787689 0.9759450943667459 1.081153188219355 0.20273822747906123 0.08597116569747687 0.5309348095082835 47.0999502625674 0.02546365889836932 0.04412465960858708 2.227808148427167e-06 5.652122211912559 0.1052080938526091 DVESYIHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DVESYIHR 8 0 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 0 ; 147.19 6.5409e-06 3906800.0 46145.0 69604.0 79829.0 70702.0 71456.0 60676.0 70110.0 52336.0 54850.0 46319.0 False True 53956.43709470587 76513.8251231893 81732.42611316839 66740.79615897685 57454.70975118802 57494.04374600664 63468.67324755622 50962.23545457568 55652.07748399476 54716.268038997754 0.9861132534888832 1.398374338481123 1.4937500133400088 1.2197614813826283 1.0500480352614419 1.0507669072939896 1.159959835022381 0.9313909241444158 1.0171029472318915 1.0 15.73968221311319 -6.164883545514128 3.67190158640799 1.0375610846011545 1.3094152154622956 0.4414036681326008 0.13280759655517882 0.22202122292796214 5.549268231819299 0.04136893471493606 0.05448577976619504 6.840950602920523e-07 6.164883545514128 0.2718541308611411 DVESYIHR ddPTM_PC-9_Lapatinib_30min_R1 2 DVESYIHR 8 0 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 0 ; 131.06 1.8003e-05 4952200.0 85957.0 124281.0 132042.0 117892.0 154700.0 157141.0 143315.0 149093.0 137405.0 116019.0 False True 84731.23741741665 123993.23498030214 121186.01645685955 126562.17095618298 145600.85015190198 150420.44574356254 150735.1494543193 156020.40507075595 121929.00196120425 136072.72956439984 0.6226908043122297 0.911227660216952 0.8905973801275532 0.9301067992193414 1.0700222639613672 1.1054415254628391 1.1077542865264571 1.1465956887189168 0.8960575888462522 1.0 17.0540184386754 -4.186913870668448 0.6566038042701702 1.063952990587203 9.671379508303555e-18 0.7099188106271179 0.07930564960540838 3.5383425455226156 0.6574094009572888 0.035083197005239826 3.362676746561897 6.502586369239077e-05 4.186913870668448 -1.063952990587203 DVGRPQPGR ddPTM_PC-9_AZD4547_30min_R2 4 DVGRPQPGR 9 1 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 0 ;;; 111.06 0.0029298 65634000.0 85714.0 96871.0 132123.0 139314.0 137277.0 114717.0 107888.0 135537.0 100349.0 106518.0 False True 112969.26903804495 128182.65633434753 130370.96269236536 107197.30967984398 118218.45812350464 107543.72785519515 117489.8229932499 114592.87098041576 105653.24327345607 102788.83724155586 1.0990421924178875 1.2470484127874284 1.2683377513648777 1.0428886302889888 1.1501098883499272 1.0462588228570502 1.1430212282404404 1.114837700820763 1.0278668978925096 1.0 16.64932407232773 -6.986200737123878 0.2495740538394749 0.9859532922386879 1.243125771632802 0.39228018673092857 0.06703940348367515 3.2666143970939916 0.5182621418125969 0.14095494837285677 0.28800865156184247 1.0322841589654643e-07 6.986200737123878 0.25717247939411403 DVGRPQPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DVGRPQPGR 9 1 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 0 ;;; 99.01299999999999 0.0055447 34172400.0 81889.0 81019.0 93548.0 87593.0 112561.0 71648.0 90798.0 67199.0 75674.0 74536.0 False True 95751.19031852599 89062.03088408252 95778.5391027658 82685.44819033745 90505.4800758993 67890.65275090448 82196.95611940672 65435.097453225986 76780.58908885712 88048.78677334847 1.0874788151823684 1.0115077577768594 1.0877894246210904 0.9390867406632518 1.02790150089035 0.7710572199667644 0.9335387701706181 0.7431686437845679 0.8720232487303036 1.0 16.42601550480829 -6.744067471050403 24.98238958688607 0.8522544518215822 1.0277598726963346 0.5236067051980209 0.07913051448049449 177.07116930567582 254643.96062481307 0.024656921094937792 0.024601530659060213 1.802737649684864e-07 6.744067471050403 0.1755054208747524 DVGRPQPGR ddPTM_PC-9_Lapatinib_30min_R1 4 DVGRPQPGR 9 1 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 0 ;;; 86.67 0.014884999999999999 63320000.0 79465.0 119543.0 104770.0 106532.0 135269.0 135341.0 116919.0 99033.0 116276.0 103865.0 False True 78331.81452790379 119266.20552820025 96156.21502389562 114366.71866033414 127312.74336908634 129552.78092528021 122972.49373093923 103634.4347177413 103179.77243943802 121817.92685858681 0.6430237038825641 0.9790529900139514 0.7893437156874229 0.93883323751764 1.0451067971044872 1.0634952035891438 1.0094778075947122 0.8507322147917199 0.8469999046955953 1.0 16.89436693187544 -4.359050097726692 2.0109695742019005 0.9491604213094275 4.539291765970804e-30 0.5025125229921833 0.08873956687902547 3.6729676022422733 5.071021037574923 0.02572184906717766 9.859644832759093 4.3747163802226326e-05 4.359050097726692 -0.9491604213094275 DVHGEQETEGRS(ph)SPGPDTLVVLEFNPASK ddPTM_PC-9_AZD4547_30min_R2 2 DVHGEQETEGRSSPGPDTLVVLEFNPASK 29 1 O60303 O60303 KIAA0556 Uncharacterized protein KIAA0556 1 DVHGEQET(0.146)EGRS(0.426)S(0.426)PGPDT(0.001)LVVLEFNPASK;DVHGEQET(0.099)EGRS(0.45)S(0.45)PGPDTLVVLEFNPASK 78.645 1.4269999999999998e-06 9272800.0 55755.0 38879.0 74124.0 107310.0 95799.0 68351.0 57894.0 68235.0 57706.0 73208.0 True False 73483.9302239563 51445.87642971678 73141.06732823877 82571.33742297288 82498.96246110831 64077.00116487042 63046.45384446102 57690.8486343115 60756.221350866086 70645.01020278085 1.0401857118149824 0.7282308585142179 1.0353323910392709 1.1688205180515718 1.1677960300989645 0.9070279837308044 0.8924402963987297 0.8166301975003548 0.8600214109456594 1.0 16.108300043294392 -6.974766666205343 24.984546463017008 0.8802409653743567 1.0214152647304506 0.2264213242558386 0.12190363388206799 366.1546288055443 362543.4875633276 0.04717252262379594 0.04160094800680479 1.059822984307329e-07 6.974766666205343 0.14117429935609394 DVHGEQETEGRS(ph)SPGPDTLVVLEFNPASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DVHGEQETEGRSSPGPDTLVVLEFNPASK 29 1 O60303 O60303 KIAA0556 Uncharacterized protein KIAA0556 1 DVHGEQET(0.099)EGRS(0.438)S(0.438)PGPDT(0.025)LVVLEFNPASK 57.145 0.00083498 3825100.0 11811.0 5816.5 13440.0 12066.0 13985.0 17471.0 12796.0 16656.0 12680.0 11163.0 True False 13810.369022116613 6393.9236800906665 13760.460571483845 11389.981138499801 11244.7396421625 16554.790004062277 11583.870244982585 16218.79764849076 12865.421011796787 13186.763533740628 1.0472902609332746 0.4848743714658036 1.0435055225093945 0.8637434886396919 0.8527293003617512 1.2554096357081075 0.8784468012445388 1.2299301194711003 0.9756314336628824 1.0 13.686802902685727 -6.668637389957602 12.061202318445819 1.0703512427720994 0.8478238993866232 0.25393773050103197 0.17903460092094264 0.6724044022202269 83.27251033114374 0.055668567317385655 0.055658875498574685 2.144680534363155e-07 6.668637389957602 -0.2225273433854762 DVIATDKEDVAFK ddPTM_PC-9_Lapatinib_30min_R1 1 DVIATDKEDVAFK 13 1 A0A5K1VW95;P40925;P40925-3;C9JRL4;C9JF79;C9JLV6 A0A5K1VW95 MDH1 Malate dehydrogenase, cytoplasmic;Malate dehydrogenase 0 100.38 0.0029425999999999996 4851200.0 35659.0 32687.0 39623.0 28115.0 38189.0 35399.0 27877.0 34371.0 34247.0 30834.0 False True 35150.496120940275 32611.31525978328 36365.34988920311 30182.670888890585 35942.79810246276 33885.0672890994 29320.3346567914 35968.00213750448 30389.742223102246 36163.61581627758 0.9719851106569578 0.9017714220131888 1.005578371199119 0.834614299693591 0.9938939260129118 0.936993343288627 0.8107688900841061 0.9945908705654081 0.8403402573871924 1.0 15.142251312264305 -5.727088934058918 24.99999352536407 0.915410256256848 0.9539775009698072 0.07465376946079416 0.06991154983459431 571.9777378239487 416276.845930022 0.0178562949348784 0.030926189304835604 1.8746105893056332e-06 5.727088934058918 0.03856724471295914 DVIEEYFK ddPTM_PC-9_AZD4547_30min_R2 2 DVIEEYFK 8 0 P25398 P25398 RPS12 40S ribosomal protein S12 0 ; 114.28 0.016975 9676600.0 54260.0 50693.0 69887.0 82763.0 79814.0 75368.0 67795.0 80705.0 64603.0 70322.0 False True 71513.55132188812 67078.52089435511 68960.25271664534 63683.2690256035 68733.20378992383 70655.22704560202 73828.62366368262 68233.89666640446 68017.7826903616 67860.0481843508 1.0538387937422635 0.9884832488200926 1.016212846317257 0.9384501003093819 1.0128670053873376 1.0411903459552188 1.0879541886430348 1.0055091101768459 1.0023244089892522 1.0 16.050274833991196 -6.52499294503495 23.662666615468627 1.031025282647104 0.996685517167971 0.11486026638320057 0.03589995377363188 66.09476791311162 739717.5119927067 0.012081675619830133 0.012174681298354405 2.9854311158295865e-07 6.52499294503495 -0.03433976547913298 DVIEEYFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DVIEEYFK 8 0 P25398 P25398 RPS12 40S ribosomal protein S12 0 ; 109.21 0.017422999999999998 11152000.0 66309.0 65707.0 65799.0 70799.0 79705.0 62493.0 71844.0 66481.0 61347.0 52512.0 False True 77533.80403755228 72229.9567175652 67367.8977040972 66832.36156345501 64087.37741712993 59215.75706736093 65038.41621448331 64735.94419244204 62244.08381787833 62032.00991523675 1.2498999168896487 1.1643981359988718 1.0860182959757654 1.0773850735253891 1.0331339820312404 0.9546000064849733 1.0484654020296078 1.0435893384866952 1.0034187817375475 1.0 15.920725250352511 -4.751393796058746 0.7475592642833968 1.013091420017733 1.4056230801254712 0.8915023148216953 0.026881903212789018 0.9323332496961462 0.38401352301927477 0.011578221334512539 0.3121571709113186 1.772581465611926e-05 4.751393796058746 0.3925316601077382 DVIEEYFK ddPTM_PC-9_Lapatinib_30min_R1 3 DVIEEYFK 8 0 P25398 P25398 RPS12 40S ribosomal protein S12 0 ;; 117.04 0.016422 47867000.0 248642.0 224750.0 260519.0 216312.0 253447.0 204387.0 237877.0 240065.0 219995.0 223055.0 False True 245096.31948464207 224229.60518359917 239100.13345242204 232220.30607567832 238539.74575597403 195645.84445936783 250193.10711890008 251219.29630037004 195216.8464499483 261609.7595478946 0.9368775840328338 0.8571148323025312 0.9139572386963967 0.887659185486787 0.9118151638081492 0.7478537681372307 0.9563599903584469 0.960282585537019 0.7462139286673236 1.0 17.9970568370951 -10.84254977065129 4.728085714013871 1.000071625599357 0.8820425175119039 0.19451146572563005 0.07325667333876325 5.309825732443425e-05 7.640316081357271e-06 0.06809370635544464 0.01650513733857613 1.4369783645327238e-11 10.84254977065129 -0.11802910808745304 DVLLQVDDER ddPTM_PC-9_Lapatinib_30min_R1 1 DVLLQVDDER 10 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 121.61 0.0014431 0.0 5324.2 6652.2 10373.0 9497.3 8233.5 12578.0 8878.0 8163.1 9427.7 7268.7 False True 5248.275931661303 6636.7972396099485 9520.171980937937 10195.763124064046 7749.221717683818 12040.068260750073 9337.65939961238 8542.387426861676 8365.853147917807 8525.085110066051 0.6156273942021254 0.7785021678872749 1.1167245673239006 1.1959720040830244 0.9089905399928351 1.4123106227448312 1.0953156806126048 1.0020295770156236 0.9813219504447844 1.0 13.057498521996234 -5.11971484907714 3.112114560426918 1.0989948457936534 0.6353535956130755 0.5880325185672634 0.1339314127034431 0.1766335705203157 3.1267148853933704 0.03553081737092454 0.13046554774806474 7.590758086764331e-06 5.11971484907714 -0.4636412501805779 DVLLQVDDERR ddPTM_PC-9_AZD4547_30min_R2 3 DVLLQVDDERR 11 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ;; 194.48 5.1945e-05 45521900.0 104110.0 105175.0 138632.0 151351.0 137111.0 134385.0 103373.0 149597.0 114481.0 126438.0 False True 137214.81437747448 139170.7619407767 136793.6490994602 116459.36529964005 118075.5043581357 125981.88470601909 112572.9967399641 126480.22104707424 120532.23194240629 122011.4441047321 1.1246061005530934 1.140636953868978 1.1211542499410083 0.9544954258526253 0.9677412248049628 1.0325415425611948 0.9226429337508191 1.036625883540123 0.9878764473842627 1.0 16.896656946641556 -5.751108683906121 24.24383279147605 0.9860550843966406 1.1299829884471915 0.8032578691984441 0.032386803458917035 57.26634471179793 134389.34445750157 0.008531676241751674 0.014558278470361511 1.7737455385300496e-06 5.751108683906121 0.1439279040505509 DVLLQVDDERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DVLLQVDDERR 11 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ;; 208.33 2.503e-06 29754100.0 79727.0 97294.0 97465.0 83590.0 111903.0 74239.0 96655.0 82158.0 67172.0 57377.0 False True 93223.20641997221 106952.70532635445 99788.93523807095 78906.72330243656 89976.41045240701 70345.77614970964 87499.13867839897 80001.43955359668 68154.2634230612 67778.99590391794 1.3753996378483304 1.5779623746266223 1.4722693056640972 1.1641766339279067 1.3274969517098727 1.037869847606334 1.2909476971661824 1.1803278948983695 1.005536634382652 1.0 16.04855064406141 -5.773824511366555 0.33633939034378363 1.0133072926257642 1.6910424079415107 0.6442640050414876 0.11306976769040368 2.2603114891281515 0.3389579430946895 0.1251019229154112 0.5924218378555633 1.6833541292083635e-06 5.773824511366555 0.6777351153157465 DVLLQVDDERR ddPTM_PC-9_Lapatinib_30min_R1 4 DVLLQVDDERR 11 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ;;; 223.77 2.5178e-13 42233500.0 85708.0 125315.0 143219.0 125860.0 132732.0 135308.0 116625.0 118998.0 141824.0 116551.0 False True 84485.78820307787 125024.84081683072 131444.08666132725 135116.1642566521 124924.96472115252 129521.19225835356 122663.27184949227 124527.08150355691 125850.28764707144 136696.6850555542 0.618052940850339 0.9146150162018927 0.9615747931846901 0.9884377532764618 0.9138843759845559 0.9475079238806378 0.8973390378826035 0.9109736746940754 0.9206535447141624 1.0 17.060618731924308 -4.761908911655716 4.764491328565816 0.9385888005260982 0.594794657800066 0.9011059685370005 0.03203793361499886 0.05419646117109238 2.975874071561657 0.00817606104246008 0.0632420234687479 1.7301792066369543e-05 4.761908911655716 -0.34379414272603215 DVLSVAFSSDNR ddPTM_PC-9_AZD4547_30min_R2 1 DVLSVAFSSDNR 12 0 D6R9L0;P63244;D6R9Z1;D6RFX4;D6RHH4;H0Y8W2;J3KPE3;H0YAM7;H0YAF8;D6RFZ9;E9PD14;D6RAU2 D6R9L0 GNB2L1 Guanine nucleotide-binding protein subunit beta-2-like 1;Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed 0 123.51 0.0026845 0.0 15618.0 10360.0 17162.0 19801.0 17052.0 16947.0 13952.0 24898.0 13105.0 17001.0 False True 20584.19912541926 13708.667399158046 16934.420666548413 15236.185372400396 14684.624138945313 15887.301410967784 15193.700971394632 21050.58619912197 13797.703545612254 16405.800164701654 1.2546903484602816 0.8355988285565799 1.0322215616757375 0.9287072388692278 0.8950873466410018 0.968395399887324 0.9261176424716578 1.2831185305069077 0.8410259424772879 1.0 14.001918340092447 DVLSVAFSSDNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DVLSVAFSSDNR 12 0 D6R9L0;P63244;D6R9Z1;D6RFX4;D6RHH4;H0Y8W2;J3KPE3;H0YAM7;H0YAF8;D6RFZ9;E9PD14;D6RAU2 D6R9L0 GNB2L1 Guanine nucleotide-binding protein subunit beta-2-like 1;Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed 0 121.61 0.0026081 0.0 12660.0 11024.0 14093.0 16824.0 16151.0 17218.0 17123.0 14536.0 14288.0 12242.0 False True 14803.087953602268 12118.389864922117 14429.030568000126 15881.40582414393 12986.32749092361 16315.057769443309 15500.985480215448 14154.445402165093 14496.934969759664 14461.37769238133 1.0236291637276689 0.8379830831267504 0.9977632058943979 1.0981945262732964 0.8980007138438256 1.1281814303237894 1.071888571749413 0.978775722704626 1.0024587752380651 1.0 13.819917379645362 -5.50754865810588 24.686833867420923 1.027127055142702 0.9275728619540383 0.2021385974803157 0.07407777781910246 801.9017935903331 1291341.0114713048 0.018849877501244023 0.037295623139165936 3.1077876884741215e-06 5.50754865810588 -0.09955419318866376 DVLSVAFSSDNR ddPTM_PC-9_Lapatinib_30min_R1 2 DVLSVAFSSDNR 12 0 D6R9L0;P63244;D6R9Z1;D6RFX4;D6RHH4;H0Y8W2;J3KPE3;H0YAM7;H0YAF8;D6RFZ9;E9PD14;D6RAU2 D6R9L0 GNB2L1 Guanine nucleotide-binding protein subunit beta-2-like 1;Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed 0 ; 187.16 0.0011842 17444800.0 47312.0 40985.0 40348.0 42473.0 41433.0 47819.0 39550.0 38259.0 53636.0 47947.0 False True 46637.322204041826 40890.101750610884 37030.74318778404 45596.606105774525 38995.99240041214 45773.89284153345 41597.70548036377 40036.6528113463 47594.948867880754 56234.57506463842 0.8293353715296132 0.7271345378463349 0.6585048992584959 0.8108286770792495 0.6934522463375687 0.813981305787747 0.7397176102522265 0.7119579505193462 0.846364515303496 1.0 15.779169804243633 -8.573873937237744 3.4383475619451005 0.9997633010634855 0.7471178739018736 0.6847830363499654 0.05283053355969866 0.1434959348038983 4.656193817518561 0.04895901649196724 0.012925617393992728 2.667632886579855e-09 8.573873937237744 -0.252645427161612 DVMEDAVEDRLDR ddPTM_PC-9_Lapatinib_30min_R1 1 DVMEDAVEDRLDR 13 1 R4GMY7;M0R1A1;Q15833-2;Q15833;Q15833-3 R4GMY7 STXBP2 Syntaxin-binding protein 2 0 95.094 0.0046698 698550.0 2594.0 2602.9 2141.0 3144.1 2503.6 2005.9 2406.4 964.83 3395.9 3152.8 False True 2557.0090843186604 2596.8731449717006 1964.9752444989995 3375.3276024101365 2356.343170266982 1920.1123329812838 2530.991617394372 1009.6595240850837 3013.4179815876705 3697.75727915807 0.6915026842705201 0.7022832892814895 0.5313964914826421 0.9128039910663508 0.6372357600506137 0.5192640262798611 0.6844666716390442 0.2730464570446251 0.8149312553780668 1.0 11.852434813988465 -8.522232950786925 24.983905843338697 1.0000000276286312 0.6228570621184192 0.38429776621735723 0.1550988304357376 57.13774018755217 2210457.8905059085 0.14844247177572095 0.038327681451923785 3.0044643087047172e-09 8.522232950786925 -0.377142965510212 DVMSDETNNEET(ph)ESPSQEFVNITK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DVMSDETNNEETESPSQEFVNITK 24 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DVMS(0.149)DET(0.082)NNEET(0.769)ESPSQEFVNITK 97.25299999999999 5.1119999999999995e-06 2992700.0 12805.0 16055.0 14204.0 22409.0 21009.0 19539.0 17259.0 16392.0 18089.0 16190.0 True False 14972.633589721718 17648.834296201432 14542.677228969966 21153.496380958244 16892.437264368404 18514.340443556328 15624.102575660703 15961.727368759635 18353.517403974154 19125.118840030522 0.782877937384771 0.9228091309561383 0.7603966987400302 1.1060582973571988 0.883259205114641 0.9680640731394682 0.816941463545738 0.8345949378024446 0.9596550775704809 1.0 14.223181092028726 -10.406975735942508 0.013257324383682387 1.9047570154428592 3.271808727513882e-06 0.11349656072596892 0.09680742444392929 8044.99895347343 21.237876126248246 1642.5062465687463 1413.141113050279 3.917637643602318e-11 10.406975735942508 -1.9047537436341317 DVMSDETNNEET(ph)ESPSQEFVNITK ddPTM_PC-9_Lapatinib_30min_R1 1 DVMSDETNNEETESPSQEFVNITK 24 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DVMSDETNNEET(0.586)ES(0.404)PS(0.01)QEFVNITK 137.64 1.9434e-08 7013100.0 60562.0 53542.0 60380.0 52559.0 57113.0 56480.0 48252.0 46148.0 59693.0 48045.0 True False 59698.37477428938 53418.0267886107 55415.78947354018 56424.36419168419 53753.72562847828 54064.48206131057 50750.25246115075 48292.20455155671 52969.745744843116 56349.514234061644 1.0594301581077952 0.9479767042307715 0.9834297638016362 1.001328315933863 0.9539341440495633 0.9594489463873703 0.9006333621678977 0.8570119052129375 0.9400213376253818 1.0 15.782115553121196 -6.764619089672089 1.6326005983228797 0.9144499491053107 0.9929408046164148 0.32840444999212093 0.04371454886474618 0.3909795627276499 2.1607040535908726 0.018445971271330387 0.016742446332149847 1.7194157885286866e-07 6.764619089672089 0.07849085551110402 DVMSDETNNEETES(ph)PSQEFVNITK ddPTM_PC-9_AZD4547_30min_R2 6 DVMSDETNNEETESPSQEFVNITK 24 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DVMSDETNNEET(0.21)ES(0.754)PS(0.036)QEFVNITK;DVMSDETNNEETES(0.999)PS(0.001)QEFVNITK;DVMSDETNNEET(0.003)ES(0.996)PSQEFVNITK;DVMSDETNNEET(0.055)ES(0.945)PS(0.001)QEFVNITK;DVMSDETNNEET(0.001)ES(0.981)PS(0.018)QEFVNITK;DVMSDETNNEET(0.027)ES(0.769)PS(0.204)QEFVNITK 170.55 1.6372e-10 64763600.0 318683.0 296325.0 425433.0 548038.0 491699.0 439323.0 362391.0 488832.0 388160.0 427060.0 True False 420017.5649818158 392106.2612987942 419791.48044701637 421696.3062026954 423435.08119254495 411852.063360512 394643.0969556097 413294.24664186686 408677.3451556539 412108.759386948 1.0191910640449209 0.9514630600962971 1.018642459994049 1.0232646033294943 1.0274838171905056 0.9993771158205473 0.9576188032078711 1.0028766368778048 0.9916735226972639 1.0 18.652665602917658 -9.845674965409705 15.342070609698862 0.999999998801539 0.9986911645032068 0.0 0.024971663001236693 0.0 0.0 0.025036004435830594 0.006072122984256579 1.426674945919563e-10 9.845674965409705 -0.0013088342983321732 DVMSDETNNEETES(ph)PSQEFVNITK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 DVMSDETNNEETESPSQEFVNITK 24 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DVMSDETNNEET(0.34)ES(0.627)PS(0.034)QEFVNITK;DVMSDETNNEETES(0.992)PS(0.008)QEFVNITK;DVMSDETNNEET(0.046)ES(0.878)PS(0.075)QEFVNITK;DVMSDETNNEET(0.003)ES(0.975)PS(0.022)QEFVNITK;DVMSDETNNEET(0.029)ES(0.959)PS(0.012)QEFVNITK 152.38 1.1700999999999998e-08 56511000.0 239072.7 254074.5 263028.6 319326.2 311987.3 282959.9 286217.0 285876.7 258684.1 226252.0 True False 279542.9862089397 279297.3372401269 269300.1993655203 301435.3882835093 250855.62818457303 268120.9847215649 259104.45372836664 278372.73953640176 262466.8655802635 267269.6965901531 1.0459209920741863 1.045001886870915 1.0075972053744684 1.1278322687878375 0.9385861225010094 1.0031851277652222 0.9694494251837779 1.0415424684799741 0.9820300203458735 1.0 18.027936746520417 -6.275287780148392 24.99963200391181 0.990927829721296 1.0522611597094333 0.43832286487384386 0.03724687362731011 809.3421572043975 1461049.8507828782 0.011215937283477915 0.01277334531774787 5.30532776403269e-07 6.275287780148392 0.06133332998813734 DVMSDETNNEETES(ph)PSQEFVNITK ddPTM_PC-9_Lapatinib_30min_R1 7 DVMSDETNNEETESPSQEFVNITK 24 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DVMSDETNNEET(0.15)ES(0.846)PS(0.004)QEFVNITK;DVMSDETNNEET(0.045)ES(0.942)PS(0.013)QEFVNITK;DVMSDETNNEET(0.122)ES(0.867)PS(0.011)QEFVNITK;DVMSDET(0.001)NNEET(0.113)ES(0.849)PS(0.037)QEFVNITK;DVMSDETNNEET(0.001)ES(0.5)PS(0.5)QEFVNITK;DVMSDETNNEET(0.061)ES(0.728)PS(0.21)QEFVNITK;DVMSDETNNEET(0.041)ES(0.948)PS(0.011)QEFVNITK 159.1 1.0813999999999998e-08 49506400.0 417265.0 342540.0 444402.0 362012.0 411566.0 383498.0 343112.0 341196.0 411897.0 326228.5 True False 411314.7245829703 341746.86967559427 407864.9830013289 388635.57011662994 387358.49704988865 367096.68451750133 360876.6605000899 357049.21175723727 365504.8223923014 382616.66155284754 1.0750047395052056 0.8931834496924848 1.0659885571789038 1.0157309107746502 1.0123931756599318 0.9594372681723831 0.9431807256784743 0.9331773747336435 0.9552768060567518 1.0 18.545540173568526 -6.7998274759271276 5.360515784424712 0.9524491147706334 1.0091011810792625 0.23114256764386676 0.048805136432454314 0.27873967115184983 19.4259016381977 0.01658420944483351 0.014951516455416603 1.585522918506186e-07 6.7998274759271276 0.05665206630862907 DVNAAIAT(ph)IK ddPTM_PC-9_AZD4547_30min_R2 3 DVNAAIATIK 10 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;Q6PEY2;P68363;P68363-2;Q71U36-2;Q71U36 Q9BQE3;P68363;Q71U36-2 TUBA1C;TUBA3E;TUBA1B;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain;Tubulin alpha-1A chain 1 DVNAAIAT(1)IK;DVNAAIAT(1)IK;DVNAAIAT(1)IK 109.44 0.0046044 20657600.0 102005.0 102236.0 109090.0 129319.0 106718.0 116233.0 96155.0 115658.0 96590.0 112454.0 True False 134440.46816419467 135281.7876660543 107643.39532186033 99506.50250863322 91902.04778676781 108964.93213554125 104712.60872308297 97785.7136564401 101695.55020760684 108517.01968833357 1.2388883195494547 1.2466412001968954 0.9919494253621935 0.9169667835922971 0.8468906356875188 1.0041275778536316 0.9649418038186354 0.9011094659371006 0.9371391741100304 1.0 16.727561805533547 -5.318843791601209 3.5615018086722143 0.9356522668276825 1.2491959554639898 0.8794434506627045 0.044334775970169917 0.06943387796328816 1.7623990144831565 0.012157792781285327 0.03009865940565567 4.799060317010276e-06 5.318843791601209 0.3135436886363072 DVNAAIAT(ph)IK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DVNAAIATIK 10 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;Q6PEY2;P68363;P68363-2;Q71U36-2;Q71U36 Q9BQE3;P68363;Q71U36-2 TUBA1C;TUBA3E;TUBA1B;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain;Tubulin alpha-1A chain 1 DVNAAIAT(1)IK;DVNAAIAT(1)IK;DVNAAIAT(1)IK 119.39 0.0019414000000000002 15758300.0 111939.0 110813.0 100427.0 127621.0 118144.0 113805.0 120277.0 131555.0 103536.0 85228.0 True False 130888.0618039716 121813.78230239592 102821.56055151843 120470.80912286435 94994.53130380048 107836.86545774757 108883.49182992915 128101.82064404436 105050.01812913183 100679.16173552298 1.3000511679646802 1.2099205059175213 1.0212794661682163 1.196581368439803 0.943537169621499 1.071094192669456 1.081489853043854 1.272376710689733 1.0434137145985658 1.0 16.619405584079345 -5.035946259951637 3.970334665202295 1.0879256243560211 1.2881113044834658 0.3915645428382942 0.0903781992639771 0.2145516010416622 7.250179179827255 0.02314890338120328 0.08387166171311888 9.205634761823422e-06 5.035946259951637 0.20018568012744464 DVNAAIAT(ph)IK ddPTM_PC-9_Lapatinib_30min_R1 3 DVNAAIATIK 10 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;Q6PEY2;P68363;P68363-2;Q71U36-2;Q71U36 Q9BQE3;P68363;Q71U36-2 TUBA1C;TUBA3E;TUBA1B;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain;Tubulin alpha-1A chain 1 DVNAAIAT(1)IK;DVNAAIAT(1)IK;DVNAAIAT(1)IK 109.44 0.0046044 21179200.0 162274.0 160483.0 134036.0 134791.0 136646.0 144464.0 133694.0 131200.0 145400.0 113953.0 True False 159959.94300259283 160111.41147354644 123016.07747392239 144703.97978959477 128608.7509363726 138285.61148203217 140616.02115023384 137296.0309691482 129023.52087012203 133649.6242171719 1.1968604022609775 1.1979937273401973 0.9204371369876005 1.0827114601868262 0.9622829221531651 1.0346876191535497 1.0521243286231916 1.0272833296265103 0.9653863347978237 1.0 17.02809625559592 -5.243135871677671 24.739773202560194 1.0104938968186008 1.1974271257088263 0.7420642890676524 0.04516156453784386 335.1002248745557 452933.2390090765 0.010818036231923029 0.02849697830746132 5.712998740595578e-06 5.243135871677671 0.18693322889022546 DVNAAIATIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DVNAAIATIK 10 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;Q6PEY2;P68363;P68363-2;Q71U36-2;Q71U36 Q9BQE3;P68363;Q71U36-2 TUBA1C;TUBA3E;TUBA1B;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain;Tubulin alpha-1A chain 0 ; 173.71 0.00073074 19876600.0 132131.0 113263.0 122679.0 152228.0 146943.0 146107.0 167280.0 152450.0 133086.0 118398.0 False True 154498.16859379286 124507.0021109104 125604.13262269835 143699.15868983464 118150.5739891516 138444.89171332653 151434.02739767762 148448.34903412705 135032.13097602432 139862.62016194794 1.1046423155443414 0.8902092779810848 0.8980536220275326 1.0274307640128888 0.8447616228864023 0.9898634213560434 1.0827340945159691 1.0613868727915838 0.9654626148120894 1.0 17.093650912187982 -7.0002456786050535 24.999998102172786 1.0330525173723903 0.9472805761853318 0.1758312449288678 0.07503951634976082 13.341850506523942 1357808.8310938962 0.025895300379802887 0.02258950515021399 9.994344640820909e-08 7.0002456786050535 -0.08577194118705855 DVNAAIATIK ddPTM_PC-9_Lapatinib_30min_R1 2 DVNAAIATIK 10 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;Q6PEY2;P68363;P68363-2;Q71U36-2;Q71U36 Q9BQE3;P68363;Q71U36-2 TUBA1C;TUBA3E;TUBA1B;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain;Tubulin alpha-1A chain 0 ; 173.71 0.00067606 71874000.0 245626.0 237710.0 241370.0 248825.0 261737.0 215168.0 235447.0 205673.0 230674.0 242747.0 False True 242123.3281977078 237159.59709985877 221525.4903151444 267124.4205558676 246342.1442547411 205965.76622110614 247637.29360898107 215229.31842620097 204693.06501509275 284705.4955099549 0.8504343330782028 0.8329997166899307 0.7780864570891242 0.9382482065455158 0.8652525087845647 0.7234344593601439 0.8698015932759621 0.7559717737119526 0.7189642217775017 1.0 18.11911081531622 DVNSS(ph)SPVMLAFK ddPTM_PC-9_AZD4547_30min_R2 1 DVNSSSPVMLAFK 13 0 Q9NRI2;C4P0D4;Q5VVQ1;C4P0D6;C4P0D8;Q99598 Q9NRI2 TRAX;DISC1;TSNAX Translin-associated protein X 1 DVNS(0.015)S(0.826)S(0.16)PVMLAFK 205.62 8.2743e-10 7949600.0 38017.0 38653.0 51226.0 47236.0 56400.0 49053.0 43985.0 55729.0 41234.0 50898.0 True False 50105.61519727648 51146.82634938766 50546.70976952619 36346.46998892509 48569.8335348649 45985.7081555557 47899.579789764386 47117.36357502084 43413.5450591206 49116.076512145446 1.020146940786004 1.0413459295092524 1.0291275964811029 0.7400116737731957 0.9888785298812401 0.9362659117159803 0.9752322089065839 0.9593063396130519 0.8838968448219857 1.0 15.58390769957052 -5.585369845566066 24.999984677666664 0.9261382727048235 1.0318840622219576 0.3137466032223222 0.07046952460778692 73.41796516324577 29370.707968284656 0.018759601812013874 0.03249258868113458 2.597946207556156e-06 5.585369845566066 0.10574578951713409 DVNSSS(ph)PVMLAFK ddPTM_PC-9_AZD4547_30min_R2 3 DVNSSSPVMLAFK 13 0 Q9NRI2;C4P0D4;Q5VVQ1;C4P0D6;C4P0D8;Q99598 Q9NRI2 TRAX;DISC1;TSNAX Translin-associated protein X 1 DVNS(0.083)S(0.199)S(0.719)PVMLAFK;DVNS(0.003)S(0.024)S(0.973)PVMLAFK;DVNS(0.089)S(0.19)S(0.721)PVMLAFK 124.09 0.0001579 15853200.0 91497.0 98364.0 118871.0 120280.0 111046.0 125805.0 106950.0 138402.0 105860.0 110560.0 True False 120591.14274417245 130158.23938714112 117294.69287106831 92551.30430747541 95629.17969348584 117938.3934623711 116468.34281039698 117015.15106156624 111455.54348252657 106689.32805184477 1.1303018300534446 1.219974310119301 1.0994041767145628 0.86748418044681 0.8963331332166199 1.1054375879568754 1.0916587904068547 1.096784028902157 1.0446737786966442 1.0 16.703056347537384 -5.525073422269285 24.99780563411392 1.0178544720729799 1.1712758879756284 0.40540263842306046 0.07862244085365735 71.61506829448722 815706.8734116863 0.023998509175623146 0.04190944304188867 2.9848779497402513e-06 5.525073422269285 0.15342141590264857 DVNSSS(ph)PVMLAFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DVNSSSPVMLAFK 13 0 Q9NRI2;C4P0D4;Q5VVQ1;C4P0D6;C4P0D8;Q99598 Q9NRI2 TRAX;DISC1;TSNAX Translin-associated protein X 1 DVNS(0.046)S(0.193)S(0.761)PVMLAFK;DVNS(0.052)S(0.197)S(0.75)PVMLAFK;DVNS(0.006)S(0.124)S(0.87)PVMLAFK 120.29 0.00018924 26746400.0 144353.0 181353.0 174733.0 174145.0 167623.0 146221.0 177895.0 130985.0 126031.0 127738.0 True False 168789.11179828993 199356.52731977665 178899.29739859235 164388.22023570767 134778.47644177347 138552.91335264078 161043.49775173294 127546.78254007924 127873.96494777266 150895.88822654833 1.1185799280685338 1.3211528137895427 1.1855809956199796 1.0894148420326906 0.8931885290301821 0.9182020463315982 1.0672490791130733 0.8452634729753948 0.8474317388674529 1.0 17.203193968730908 -5.99093564246599 2.492817498730464 0.9271289549230534 1.2228304169869744 0.7211503674928297 0.07855444435716473 0.1478745746282893 1.8510091473911807 0.024564577072694226 0.03760450988578818 1.0210907866113629e-06 5.99093564246599 0.295701462063921 DVNSSS(ph)PVMLAFK ddPTM_PC-9_Lapatinib_30min_R1 4 DVNSSSPVMLAFK 13 0 Q9NRI2;C4P0D4;Q5VVQ1;C4P0D6;C4P0D8;Q99598 Q9NRI2 TRAX;DISC1;TSNAX Translin-associated protein X 1 DVNSS(0.064)S(0.935)PVMLAFK;DVNS(0.078)S(0.134)S(0.788)PVMLAFK;DVNS(0.01)S(0.219)S(0.772)PVMLAFK;DVNS(0.05)S(0.391)S(0.559)PVMLAFK 182.37 6.9977e-05 27189600.0 121218.0 157115.0 173441.0 147157.0 187435.0 177047.0 167490.0 159164.0 174111.0 149558.0 True False 119489.40909134115 156751.20987061702 159181.3504816208 157979.41668136162 176410.4418113882 169475.11252671503 176161.81266513577 166559.340496749 154500.78570988853 175408.90102649175 0.6812049353943267 0.8936331563182368 0.9074873028112744 0.9006351203209592 1.0057097489297033 0.9661716796294132 1.0042923228766498 0.9495489654290337 0.8808035670125686 1.0 17.420362432829243 -4.127782670228526 1.0419970109128867 0.9598849087058924 1.8081247136708508e-13 0.799084947109401 0.04099124906513417 2.67087859392224 0.8973358894029404 0.013190725766289197 3.960166623761305 7.451047461614989e-05 4.127782670228526 -0.9598849087057115 DVPGGGPSSSAPAGAEADGPKAS(ph)PEAR ddPTM_PC-9_AZD4547_30min_R2 2 DVPGGGPSSSAPAGAEADGPKASPEAR 27 1 Q8N3F8;B0QY86 Q8N3F8 MICALL1 MICAL-like protein 1 1 DVPGGGPSSSAPAGAEADGPKAS(1)PEAR;DVPGGGPSSSAPAGAEADGPKAS(1)PEAR 142.89 9.192799999999999e-13 15558900.0 38508.0 56802.0 40838.0 29606.0 26436.0 44865.0 48140.0 52740.0 43444.0 37736.0 True False 50752.742983842065 75162.13567634896 40296.461436924845 22780.794108140315 22765.817718576018 42059.58445760724 52424.36674046284 44590.24484463382 45740.36114731614 36414.87412594448 1.3937366035732717 2.0640504046888424 1.1065934567714146 0.6255903570983292 0.6251790858822733 1.155011117493911 1.439641575009924 1.2245063566721115 1.2560900523538414 1.0 15.152240237791363 -5.348005971835516 7.356301713929481 1.0462234279029217 1.7260171177969152 0.469223659926584 0.2873092237384885 0.22915847883686324 16.912763863497688 0.08284133916334203 0.17383499698244465 4.487392194305259e-06 5.348005971835516 0.6797936898939936 DVPGGGPSSSAPAGAEADGPKAS(ph)PEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DVPGGGPSSSAPAGAEADGPKASPEAR 27 1 Q8N3F8;B0QY86 Q8N3F8 MICALL1 MICAL-like protein 1 1 DVPGGGPSS(0.001)SAPAGAEADGPKAS(0.998)PEAR 108.99 1.7024999999999998e-10 9537000.0 23565.0 44217.0 32613.0 22808.0 28414.0 13686.0 22805.0 13581.0 11560.0 18515.0 True False 27554.089070034563 48606.57154002735 33390.61760549125 21530.14170453368 22846.480671605663 12968.282067173961 20644.74530609783 13224.513140258958 11729.043130628625 21871.622935340634 1.2598099899350441 2.2223577867871804 1.5266639199205458 0.9843870191152947 1.0445718060862248 0.5929272878154613 0.9439055056467534 0.604642516897569 0.536267617876522 1.0 14.41677265589779 -5.806842518170282 2.1124645726952442 0.7667349898387983 1.7751111708680694 0.6800293695308134 0.27306042983014517 0.16499561288088851 1.5035605153558598 0.08074142005218678 0.14950165497422294 1.5601181229917945e-06 5.806842518170282 1.008376181029271 DVPGGGPSSSAPAGAEADGPKAS(ph)PEAR ddPTM_PC-9_Lapatinib_30min_R1 2 DVPGGGPSSSAPAGAEADGPKASPEAR 27 1 Q8N3F8;B0QY86 Q8N3F8 MICALL1 MICAL-like protein 1 1 DVPGGGPS(0.001)S(0.005)S(0.057)APAGAEADGPKAS(0.938)PEAR;DVPGGGPSSSAPAGAEADGPKAS(1)PEAR 132.86 1.7100000000000002e-12 14581200.0 14465.8 47416.0 37942.0 39638.0 60371.0 46052.0 63476.0 60830.0 38752.0 43444.0 True False 14259.515039297175 47306.21116523037 34822.55522035544 42553.11074849176 56820.09647395268 44082.46331245529 66762.47668954666 63656.383870832826 34387.341683349165 50953.23751450871 0.27985493630776337 0.9284240506162171 0.6834218377279729 0.8351404704436091 1.115142025229965 0.8651552965580058 1.3102695715956485 1.2493098962103624 0.6748804072274607 1.0 15.636886196161074 -4.689761109636292 0.6677499930642158 1.0571005072400002 2.1217350241934445e-13 0.47617560851505747 0.20909908723526427 3.2968826628105603 1.021904196334111 0.09368240592475914 2.7343077222056733 2.042861342991967e-05 4.689761109636292 -1.0571005072397879 DVPPDILLDS(ph)PER ddPTM_PC-9_AZD4547_30min_R2 17 DVPPDILLDSPER 13 0 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER 165.34 3.3973000000000004e-18 11218220.0 55498.13 56444.08 86211.19999999998 107851.80000000003 92884.29999999999 80885.12 70169.2 89899.65000000001 70605.59999999999 76168.29999999999 True False 73145.38090718439 74688.52503585603 85067.98315860248 82988.23380369943 79988.91824472441 75827.36065983947 76414.12286424766 76007.72478094194 74337.66787181082 73501.67100082629 0.9951526259363832 1.0161473068417233 1.1573612137014704 1.1290659473954885 1.088259860702013 1.0316413168210425 1.0396242945740464 1.0340951946532952 1.011373848507133 1.0 16.16548942837195 -6.800149456214124 6.350795147025409 1.0260778488059248 1.0811586438897398 0.2543400849026526 0.04576211973080822 0.30725941035850984 32.92574628671498 0.01795628698329021 0.01608516726946642 1.5843478680492092e-07 6.800149456214124 0.055080795083815026 DVPPDILLDS(ph)PER ddPTM_PC-9_LapatinibAZD4547_30min_R1 18 DVPPDILLDSPER 13 0 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER 168.1 5.1068e-05 11743670.0 57854.149999999994 63470.3 74608.59999999999 75050.0 87938.7 74868.9 76853.29999999999 68464.5 70522.4 53043.02 True False 67647.71492345179 69771.21192340052 76387.55197869125 70845.19181538279 70707.74300823985 70942.6430848342 69573.19905429184 66667.37941913394 71553.65668472696 62659.2996376847 1.0796117306546935 1.1135013051029787 1.2190936129255756 1.13064129706255 1.1284477071574965 1.132196553345574 1.110341153772631 1.063966239722199 1.1419479167254047 1.0 15.935241023901156 -9.903151743678078 0.3598521054554878 0.9648995816818102 1.1395237882364753 0.4828360954850516 0.03892479388312747 6.506238040938439 0.9132424722192956 0.3309772788888657 0.03296372339032115 1.2498222626063217e-10 9.903151743678078 0.17462420655466504 DVPPDILLDS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 20 DVPPDILLDSPER 13 0 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER 166.03 3.1599e-18 10176630.0 91402.51000000001 82430.0 95732.2 75444.32 83402.41 91278.74 75637.67000000001 72016.49 90878.53999999996 71592.51999999999 True False 90099.0934462325 82239.13839948426 87861.46805297861 80992.74696767378 78496.84421924691 87374.96107133557 79553.81845463834 75362.63903452238 80642.8418317484 83967.1916909635 1.0730273530861567 0.9794198989310106 1.0463785471871891 0.964576108079963 0.9348513703798753 1.04058453440856 0.9474393135289276 0.8975248250756117 0.9604089431566297 1.0 16.357538116600608 -1.5228812027160932 0.3966031628680584 0.9530651879325707 2.664307442927918 0.34836565062636216 0.0422996319197086 81.53632877068672 1.0873164399604558 0.03128793186402099 108.72656128606792 0.029999830246832136 1.5228812027160932 1.7112422549953472 DVPPDILLDS(ph)PERK ddPTM_PC-9_AZD4547_30min_R2 10 DVPPDILLDSPERK 14 1 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK 131.24 2.495e-05 51064600.0 253515.6 244903.30000000002 289601.0 345367.0 321094.0 308496.7 285856.0 298045.1 277042.2 295277.0 True False 334128.2873479412 324063.5023799442 285760.7015180679 265747.974016959 276515.6405858848 289206.35258092347 311296.6302235504 251989.07819005224 291686.0850991391 284939.44210532465 1.172629120346331 1.1373065799018367 1.002882224400649 0.9326472040986459 0.9704365199243772 1.0149747976063686 1.0925010167896767 0.8843601164099539 1.0236774626354488 1.0 18.12029581175755 -5.237041471533174 3.6201127329636043 0.9866922376728242 1.1641268726876495 0.6172587073702133 0.05228735414780314 0.1460816391104434 4.135756598575983 0.01392640317994365 0.039545047594858475 5.793733684176152e-06 5.237041471533174 0.17743463501482526 DVPPDILLDS(ph)PERK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 DVPPDILLDSPERK 14 1 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK 125.39 0.00030477 33645900.0 188885.9 203990.0 197594.1 268101.0 248967.6 234169.19999999998 246639.9 211763.0 225565.9 195314.5 True False 220860.55220342203 224240.7790770554 202305.4927237973 253080.17016516902 200184.1860088705 221888.95492068306 223276.38315375775 206204.44563144541 228864.3745587419 230723.4727412683 0.9572522014311631 0.9719027561990515 0.8768309973847406 1.0968982356163275 0.8676368452262144 0.961709497019871 0.9677228783919108 0.8937298107621743 0.9919423101583982 1.0 17.815805259059275 -8.493306525821936 24.12145218092568 1.0000001098277167 0.9502944636841277 0.08507782818111953 0.06153923116247651 920.1100842444948 750515.8369638898 0.05543469212981379 0.01431317594478331 3.2113931315495708e-09 8.493306525821936 -0.049705646143588966 DVPPDILLDS(ph)PERK ddPTM_PC-9_Lapatinib_30min_R1 11 DVPPDILLDSPERK 14 1 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK 127.75 4.0855e-05 39683100.0 322759.0 293004.9 323012.0 288031.0 300596.0 313613.0 277594.6 285510.0 296887.1 236776.0 True False 318156.39747324766 292326.4651562171 296455.20022237796 309213.76058324834 282915.53427447466 300200.5030576098 291967.0901071903 298775.83690549876 263448.5484382393 277702.4161158122 1.1456738544923737 1.0526608635421673 1.0675283433571034 1.1134716251596988 1.018772318338377 1.081015092545738 1.0513667622734302 1.0758849025674238 0.9486721510135205 1.0 18.083180203639436 -8.253042991750329 24.716029082401644 0.9743360742610401 1.0734645467396424 0.5749888007676711 0.034846059149919464 324.2230018951278 954406.5592814926 0.023210759800814905 0.008439777993250486 5.58414913300303e-09 8.253042991750329 0.09912847247860235 DVPSPGGLSAPS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DVPSPGGLSAPSSPR 15 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 DVPSPGGLSAPS(0.5)S(0.5)PR;DVPSPGGLSAPS(0.5)S(0.5)PR 137.73 3.126e-05 28057000.0 31257.0 34761.0 55516.0 45313.0 70644.0 74096.0 76650.0 79920.0 65823.0 55387.0 True False 36548.192746109504 38211.842352554224 56839.71198560244 42774.2595167281 56801.81532219723 70210.27532144684 69389.1571020566 77822.18468223965 66785.53685011828 65428.22465674925 0.5585997929463822 0.5840268867605974 0.8687338267818816 0.6537585230400368 0.8681546170661355 1.0730884979652937 1.0605385896696307 1.1894283406054775 1.0207450561357854 1.0 15.997625504388768 -6.45031361484893 1.2429310855902023 1.0956617197777052 0.6405439221698187 0.8055011837112351 0.0926760689805624 0.18947761171070204 0.6070462523695396 0.04058263474480569 0.048955438747197044 3.5455726214784064e-07 6.45031361484893 -0.4551177976078865 DVPSPGGLSAPS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 2 DVPSPGGLSAPSSPR 15 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 DVPSPGGLSAPS(0.5)S(0.5)PR;DVPSPGGLS(0.014)APS(0.67)S(0.316)PR 179.79 2.7000999999999998e-05 45355000.0 49232.0 58984.0 77861.0 66666.0 85856.0 99405.0 115962.0 118685.0 106296.0 102663.0 True False 48529.94265195693 58847.42617196613 71459.5691321515 71568.84003125678 80806.11887939052 95153.67987437281 121965.94495357634 124199.53838089442 94323.82513349704 120408.16276015119 0.4030452881224246 0.48873286347860095 0.5934777800280571 0.5943852841091795 0.6711016680850239 0.7902593785432603 1.0129375131861136 1.0314876959653934 0.7833673645646996 1.0 16.877573673630827 -6.549044512196916 0.9144797563604088 0.9715266720863455 0.46925103063653684 0.8594670091470034 0.08000467947613389 0.20601992219360302 0.3766337393631738 0.04596401409023692 0.05338386111900261 2.8245904589873624e-07 6.549044512196916 -0.5022756414498086 down DVPSPGGLSAPSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 DVPSPGGLSAPSSPR 15 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 DVPSPGGLSAPS(0.153)S(0.847)PR;DVPSPGGLSAPS(0.002)S(0.998)PR 213.0 1.4221000000000002e-17 70488000.0 166535.0 156375.0 253680.0 270070.0 247370.0 212979.0 215047.0 296650.0 234780.0 229280.0 True False 219489.66585681294 206920.16067020636 250316.0374484326 207809.53403990573 213026.94541701267 199661.38946164527 234185.7663987596 250809.558838844 247189.99148713023 221252.97698740003 0.9920303394123935 0.9352197809387672 1.131356697915471 0.9392394934949966 0.9628206965510985 0.9024122169122978 1.0584524989785609 1.1335872730567922 1.1172278667292566 1.0 17.75533734141127 -7.504693165193264 18.616190822531543 1.0944488596070785 0.9799471791416043 0.3542609533195046 0.06633609381560505 28.05715767194024 28723.961452434458 0.028471106622491305 0.018617290707012017 3.1282887640158256e-08 7.504693165193264 -0.11450168046547415 DVPYPPPLS(ph)PAIEAIQK ddPTM_PC-9_AZD4547_30min_R2 1 DVPYPPPLSPAIEAIQK 17 0 G3V2R9;G3V3Y1;Q8N8N7 G3V2R9 PTGR2 Prostaglandin reductase 2 1 DVPYPPPLS(1)PAIEAIQK 134.21 7.4088e-06 0.0 11127.0 9167.6 12702.0 19355.0 16639.0 9405.6 9389.3 12109.0 11548.0 12973.0 True False 14665.154544022296 12130.84741781093 12533.563180660643 14893.00378176909 14328.962060046395 8817.466345134746 10224.92951051573 10237.832287138237 12158.40370429075 12518.819218673878 1.171448703576357 0.9690089141726542 1.0011777438214597 1.189649241004593 1.1445937360188405 0.7043369019964794 0.8167646909752931 0.8177953613921373 0.9712101031185505 1.0 13.611810872514958 -6.748256020716858 24.99737689478655 0.8478050641299415 1.0881928584933067 0.5665335443161195 0.10149967286121081 172.4053537646618 326902.58301421657 0.034307800104208926 0.0341117434808847 1.7854347338401854e-07 6.748256020716858 0.24038779436336521 DVPYPPPLS(ph)PAIEAIQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DVPYPPPLSPAIEAIQK 17 0 G3V2R9;G3V3Y1;Q8N8N7 G3V2R9 PTGR2 Prostaglandin reductase 2 1 DVPY(0.01)PPPLS(0.99)PAIEAIQK;DVPY(0.018)PPPLS(0.982)PAIEAIQK;DVPYPPPLS(1)PAIEAIQK;DVPY(0.004)PPPLS(0.996)PAIEAIQK 171.78 1.2283e-07 3013300.0 27276.800000000003 26151.2 28830.300000000003 28567.0 38046.1 35579.5 39197.0 31798.1 31821.1 29809.6 True False 31894.223498642852 28747.318308740138 29517.723691521616 26966.4836054636 30591.239821214083 33713.64838586993 35483.976398294944 30963.43356787189 32286.423387893286 35213.844507336216 0.9057296624342799 0.8163640951714635 0.8382420069291807 0.7657920906604101 0.8687276339520642 0.9573975479685626 1.0076711842952124 0.8792971628366557 0.9168673241902613 1.0 15.103855123049495 -6.630529808794018 4.292266964417355 0.9478301122432163 0.8294998154880081 0.5954908091239511 0.04727034424062313 0.16113204117359473 5.28981149561718 0.016378988996551318 0.016332829636839002 2.3413707643221443e-07 6.630529808794018 -0.11833029675520823 DVPYPPPLS(ph)PAIEAIQK ddPTM_PC-9_Lapatinib_30min_R1 2 DVPYPPPLSPAIEAIQK 17 0 G3V2R9;G3V3Y1;Q8N8N7 G3V2R9 PTGR2 Prostaglandin reductase 2 1 DVPYPPPLS(1)PAIEAIQK;DVPY(0.067)PPPLS(0.933)PAIEAIQK 141.1 5.8176e-08 0.0 15377.800000000001 16550.0 16019.199999999999 13034.7 17155.2 16304.1 15549.4 15705.0 19093.9 16048.4 True False 15158.509752056854 16511.679491828974 14702.163211900224 13993.31532048453 16146.164864420896 15606.811649713412 16354.471848201478 16434.711633921255 16943.343914319266 18822.34455685116 0.8053465234509958 0.8772381911274106 0.7811015873975579 0.7434416726470503 0.8578190041975319 0.8291640609688381 0.8688860093281313 0.873149016281246 0.900171807138237 1.0 14.20015872439956 -8.474473722231233 0.5541128729676837 1.002023083244798 0.8081089109853453 0.7268678561653407 0.035101527196846144 0.5152533247164779 0.3828551252929359 0.04036211155776292 0.018656183554024285 3.353715960982981e-09 8.474473722231233 -0.19391417225945273 DVQCGAGT(ph)CCAISLWLR ddPTM_PC-9_Lapatinib_30min_R1 1 DVQCGAGTCCAISLWLR 17 0 P58294 P58294 PROK1 Prokineticin-1 1 DVQCGAGT(0.748)CCAIS(0.252)LWLR 77.24 0.019089 17347000.0 22489.0 13574.0 118300.0 23121.0 68866.0 80609.0 36416.0 46460.0 120390.0 38597.0 True False 22168.302736022502 13542.57023698408 108573.83065120575 24821.395469394967 64815.43727576537 77161.54097875676 38301.442295143526 48618.701210568695 106830.41043709747 45268.440022730254 0.4897076798955591 0.29916140759840776 2.3984442714767398 0.5483156799070525 1.4318018744012417 1.7045328034280018 0.8460959175070215 1.0740087616484288 2.359931342530373 1.0 15.46621797086574 -5.203067210612772 24.996960348771292 1.3819354620592172 0.3944323315374044 0.3338255783281895 0.5776864941245393 300.0199078420579 128477.40196918284 0.13988754769171335 0.3701075653934076 6.265168985700442e-06 5.203067210612772 -0.9875031305218128 DVQIGDIVTVGECRPLSK ddPTM_PC-9_Lapatinib_30min_R1 1 DVQIGDIVTVGECRPLSK 18 1 P62280;M0R1H5 P62280 RPS11 40S ribosomal protein S11 0 114.58 0.00018128 5972800.0 26142.0 25469.0 31481.0 26244.0 30599.0 28574.0 27307.0 23433.0 27409.0 27744.0 False True 25769.210286144335 25410.0280953107 28892.753700174217 28174.07130741755 28799.22697994864 27351.9566292473 28720.822845822848 24521.782726372287 24321.909790434485 32539.513433443743 0.7919359439363661 0.7808976046087573 0.8879282647932458 0.8658418130635156 0.8850540140636867 0.8405766940920287 0.8826445086392691 0.7536001660420981 0.7474576975523151 1.0 14.989905057959827 -11.88316634781829 2.309222615473222 2.157896425722441 0.8295398004857923 0.500428195727296 0.0519954009909323 2645824.9246486174 418682.1380766724 16067841.951493131 0.014480447439154099 1.3086805630628162e-12 11.88316634781829 -1.3283566252366485 DVQS(ph)PGFLNEPLSSK ddPTM_PC-9_AZD4547_30min_R2 1 DVQSPGFLNEPLSSK 15 0 Q8NG31-2;Q8NG31;Q8NG31-4;H0YCZ2;E9PPJ1;Q8NG31-3 Q8NG31-2 CASC5 Protein CASC5 1 DVQS(0.998)PGFLNEPLS(0.002)SK 156.11 0.00020527 3514800.0 12784.0 16064.0 11110.0 12896.0 14461.0 18150.0 14805.0 18094.0 15365.0 13915.0 True False 16849.046076281204 21256.373851358574 10962.674140854951 9923.026441213859 12453.3397650298 17015.077630793967 16122.616318914676 15297.98805875624 16177.16253173081 13427.840085396372 1.2547845349011573 1.583007670345749 0.8164138142200215 0.7389890241548065 0.9274268747490966 1.2671492602372396 1.2006857555928927 1.1392739235399274 1.2047479288440812 1.0 13.712939640480736 -5.2557923822620305 24.99399046432038 1.0413423059818192 1.418896101935687 0.4192961395499277 0.17978672344614513 489.1592680994621 2165035.5544456425 0.05153901893016358 0.12864503635059443 5.5489091933129e-06 5.2557923822620305 0.37755379595386773 DVQS(ph)PGFLNEPLSSK ddPTM_PC-9_Lapatinib_30min_R1 1 DVQSPGFLNEPLSSK 15 0 Q8NG31-2;Q8NG31;Q8NG31-4;H0YCZ2;E9PPJ1;Q8NG31-3 Q8NG31-2 CASC5 Protein CASC5 1 DVQS(1)PGFLNEPLSSK 105.0 0.0010925999999999998 2194800.0 6822.3 9116.7 11088.0 8898.4 13188.0 13825.0 14984.0 14411.0 17321.0 12891.0 True False 6725.012750943407 9095.590841278374 10176.387440917752 9552.81802019222 12412.307768605597 13233.73697764905 15759.79820272491 15080.587669942 15370.12658178393 15119.192173822204 0.4447997401995646 0.6015923824969125 0.6730774583669513 0.6318338910151721 0.8209636881325324 0.8752939195099534 1.04237038735521 0.9974466556522084 1.016597077745741 1.0 13.884093437233087 -6.326505282075769 0.7183439957603698 1.0371502799275178 0.49999821561304036 0.9393008136219861 0.04924929953016198 0.17187638917603124 0.1932357646731103 0.031217256410012877 0.051817448973236736 4.715141365444002e-07 6.326505282075769 -0.5371520643144775 down DVQSPAPS(ph)ENPDVS(ph)HPEEES(ph)NIIMSTKL ddPTM_PC-9_AZD4547_30min_R2 1 DVQSPAPSENPDVSHPEEESNIIMSTKL 28 1 A0A2R8YHG5;Q9BZV2 A0A2R8YHG5 SLC19A3 Thiamine transporter 2 3 DVQS(0.589)PAPS(0.686)ENPDVS(0.724)HPEEES(0.918)NIIMS(0.042)T(0.04)KL 48.085 0.031627999999999996 0.0 10592.0 6430.3 9100.4 16754.0 14858.0 15979.0 9247.2 11529.0 14098.0 9116.0 True False 13960.035672713586 8508.768723629923 8979.722749904275 12891.624146719685 12795.223167748627 14979.830603992095 10070.182885799908 9747.45796006415 14843.191498362574 8796.851614694448 1.5869354496550159 0.9672515914008024 1.0207882482528585 1.465481596300345 1.4545230189372769 1.7028627127197948 1.1447485221847395 1.1080621098327712 1.6873299844649183 1.0 13.102771561527062 -4.4528556927133796 20.386345240897978 1.2971702649606995 9.342181255030269 0.1036181433016069 0.2650353488860025 406.9698774159604 119353.3650743534 0.06542213176502065 1086.1125900924542 3.5248797622226926e-05 4.4528556927133796 8.045010990069569 DVS(ph)PDPSLSTPGSAGSAR ddPTM_PC-9_AZD4547_30min_R2 2 DVSPDPSLSTPGSAGSAR 18 0 P23771;P23771-2 P23771 GATA3 Trans-acting T-cell-specific transcription factor GATA-3 1 DVS(1)PDPSLSTPGSAGSAR;DVS(1)PDPSLSTPGSAGSAR 172.42 4.1072e-08 7778900.0 14956.6 19886.5 23209.0 19838.7 19559.2 20102.6 20676.4 26217.0 20136.9 20159.0 True False 19712.487683393894 26314.422223296966 22901.233495508783 15265.194219859595 16843.742696367543 18845.581244121135 22516.559544505715 22165.76505672669 21201.295423703872 19453.23954592206 1.0133267334142388 1.3527012897352204 1.1772452316462385 0.7847121906777529 0.8658579799321116 0.9687631306669275 1.1574709441762778 1.1394382413479944 1.0898593714252727 1.0 14.247722806620116 -5.555623962649328 24.999244055447946 1.0042996601773704 1.2035040972337667 0.27647524675441426 0.13271686483323955 235.73151948403745 179967.46749099594 0.0391052874583204 0.06773287236614704 2.782121147014831e-06 5.555623962649328 0.19920443705639634 DVS(ph)PDPSLSTPGSAGSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DVSPDPSLSTPGSAGSAR 18 0 P23771;P23771-2 P23771 GATA3 Trans-acting T-cell-specific transcription factor GATA-3 1 DVS(0.976)PDPS(0.02)LS(0.004)TPGSAGSAR;DVS(0.982)PDPS(0.012)LS(0.004)T(0.002)PGSAGSAR 110.6 0.0022714000000000002 0.0 20398.7 24568.0 20825.0 22426.0 25740.0 18648.6 24666.0 16859.1 18451.0 17177.9 True False 23851.79701731015 27006.94867574443 21321.546979252293 21169.54392607299 20696.43177613607 17670.634587015946 22329.45791362461 16416.56648869301 18720.810969137437 20292.117289818423 1.1754217993446054 1.3309083665357668 1.0507305213512828 1.0432397774822058 1.0199247067490838 0.8708127562362451 1.1004005937235748 0.8090120047221503 0.9225656791630419 1.0 14.308631784030723 -5.615304936182722 1.1524717747104471 0.9425018831585297 1.2708673934915005 0.6082001979141407 0.08938480499479723 0.37377061855633814 0.9083934455139954 0.03050351752945916 0.10477923113035059 2.424906869432039e-06 5.615304936182722 0.3283655103329708 DVS(ph)PDPSLSTPGSAGSAR ddPTM_PC-9_Lapatinib_30min_R1 2 DVSPDPSLSTPGSAGSAR 18 0 P23771;P23771-2 P23771 GATA3 Trans-acting T-cell-specific transcription factor GATA-3 1 DVS(1)PDPSLSTPGSAGSAR;DVS(1)PDPSLSTPGSAGSAR 169.15 8.8585e-08 7789700.0 18327.3 30577.0 30170.0 15580.599999999999 20574.7 28558.0 32418.0 31464.0 25197.0 20761.0 True False 18065.949341184798 30506.200835145293 27689.539059567865 16726.44929935795 19364.53659741655 27336.6409119495 34096.445417507784 32925.93230497922 22359.04852382713 24349.511187706394 0.7419429984412153 1.2528465397098933 1.1371702226838865 0.6869316254612462 0.7952741411578454 1.12267719467614 1.400292808946507 1.3522214902450649 0.9182545124403068 1.0 14.571605190290319 -6.957801033131656 8.323478139889733 1.20618827795629 0.9411991640710896 0.22992628497178647 0.21109798811220198 0.3773342335129975 66.64855975640634 0.07802999461655638 0.0686056226623393 1.1020440823363924e-07 6.957801033131656 -0.2649891138852004 DVS(ph)SPDENNGQSK ddPTM_PC-9_AZD4547_30min_R2 2 DVSSPDENNGQSK 13 0 J3QL74;J3QLI2;O43829 J3QL74 ZBTB14 Zinc finger and BTB domain-containing protein 14 1 DVS(0.5)S(0.5)PDENNGQSK;DVS(0.923)S(0.077)PDENNGQSK 218.45 1.2340999999999999e-14 7345300.0 33933.0 32733.0 39898.0 51384.0 44026.0 42088.0 38449.0 42030.0 34981.0 40480.0 True False 44722.98814975361 43313.30212129734 39368.9264511099 39538.212674886236 37913.74984407731 39456.23070660366 41870.886514417456 35535.229253317404 36830.02424487308 39062.80752115306 1.1448994833649753 1.1088118051382398 1.0078365829130709 1.0121702761245652 0.9705843550427471 1.0100715542588063 1.0718862563000313 0.9096947072755736 0.9428411981122735 1.0 15.253508021843437 -5.1790479998490175 1.6893676903250912 0.9868374820495734 1.158065412205577 0.6469391003522202 0.040910746414812654 0.33026155691786696 1.5138399629966293 0.012588587366229798 0.07113007500938152 6.621433171036958e-06 5.1790479998490175 0.17122793015600346 DVSELTGFPEMLGGR ddPTM_PC-9_Lapatinib_30min_R1 2 DVSELTGFPEMLGGR 15 0 P31939-2;P31939;F8WEF0 P31939-2 ATIC Bifunctional purine biosynthesis protein PURH;Phosphoribosylaminoimidazolecarboxamide formyltransferase;IMP cyclohydrolase 0 ; 152.96 0.00070623 5677700.0 19781.2 14862.4 17924.8 14992.2 17906.8 16202.099999999999 15711.5 14481.599999999999 16464.4 15461.400000000001 False True 19499.116460572186 14827.987025943132 16451.092135728937 16094.776400513087 16853.55723012333 15509.173951939805 16524.96459304009 15154.468003679971 14610.00589418182 18133.882388979495 1.0752863640729458 0.8176951139241173 0.9072018767325171 0.8875527068761826 0.9293959709568725 0.85525943199925 0.9112756021337609 0.8356990344709524 0.8056744595994931 1.0 14.146400212722984 -4.7498230798447985 24.994942127475735 0.8804889773427637 1.0752867967023712 0.519871215109688 0.055289270244938606 406.3117482920305 874211.5421878842 0.013044994306137373 0.20518853653789967 1.7790039818989378e-05 4.7498230798447985 0.1947978193596075 DVSGFSDPYCLLGIEQGVGVPGGSPGS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 DVSGFSDPYCLLGIEQGVGVPGGSPGSR 28 0 K7EIH3;K7EQ37;K7EN81;Q70J99-2;Q70J99;Q70J99-3 K7EIH3 UNC13D Protein unc-13 homolog D 1 DVSGFSDPYCLLGIEQGVGVPGGS(0.32)PGS(0.68)R 119.41 1.2649999999999998e-12 9414300.0 9291.2 10221.0 15239.0 19044.0 17154.0 13555.0 13321.0 15941.0 12393.0 13124.0 True False 12245.608331034415 13524.738367451195 15036.920903014283 14653.700026866993 14772.463199593485 12707.403707185236 14506.543193803594 13477.684737738111 13048.068679189062 12664.53275463471 0.9669214465534083 1.0679224121001767 1.1873253592803392 1.1570659818858557 1.1664436016549726 1.003385119165556 1.1454463796538235 1.0642070259406782 1.030284253827998 1.0 13.628506230780186 -8.227876248084002 2.095017121857455 1.0035551477897033 1.1028411621488377 0.19445344796464537 0.06783575834468769 0.5344021567932933 4.238831901386943 0.06548699058733312 0.019307205108858368 5.917302232776342e-09 8.227876248084002 0.09928601435913431 DVSS(ph)PDENNGQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DVSSPDENNGQSK 13 0 J3QL74;J3QLI2;O43829 J3QL74 ZBTB14 Zinc finger and BTB domain-containing protein 14 1 DVS(0.029)S(0.959)PDENNGQS(0.012)K 131.35 0.00051986 0.0 13328.0 14766.0 12970.0 15365.0 17710.0 15122.0 17880.0 12989.0 13468.0 11430.0 True False 15584.167160000881 16231.870894905664 13279.253988998908 14504.148864002116 14239.852632298736 14328.975699240433 16186.276960010047 12648.0525129831 13664.94402104725 13502.16852016979 1.154197352574956 1.2021677014812986 0.9834904644511074 1.0742088459594878 1.054634491565335 1.0612351399581144 1.198790915387457 0.936742308769825 1.0120555080196416 1.0 13.720903509940639 -1.5228787452803376 0.4293489804889898 1.0330186298113981 4.012668955438846 0.2700172942343144 0.07395476124630095 115.37603115260451 1.4519499688505202 0.05015747308902548 297.2413339695047 0.029999999999999995 1.5228787452803376 2.979650325627448 DVSS(ph)PDENNGQSK ddPTM_PC-9_Lapatinib_30min_R1 2 DVSSPDENNGQSK 13 0 J3QL74;J3QLI2;O43829 J3QL74 ZBTB14 Zinc finger and BTB domain-containing protein 14 1 DVSS(1)PDENNGQSK;DVS(0.022)S(0.978)PDENNGQSK 257.81 5.938599999999999e-44 10722900.0 64637.0 59570.0 55502.0 48453.0 55284.0 53214.0 46749.0 45299.0 59560.0 44200.0 True False 63715.264527025945 59432.069324969874 50938.83980391564 52016.395254469746 52032.303812525926 50938.161267892705 49169.43447538624 47403.756912129844 52851.725605395215 51839.91110720209 1.2290774263726316 1.1464539204565305 0.982618193510728 1.0034044068266763 1.0037112854018206 0.9826051044446312 0.9484860877501612 0.9144258911652352 1.0195180600541685 1.0 15.66177562390415 -5.10890796268252 2.22116841667856 0.9767767899303689 1.235661126906639 0.88797758443614 0.0298630136703147 0.11307664271443214 0.9674122165114479 0.008593801476639806 0.04356685365689453 7.782014529401036e-06 5.10890796268252 0.2588843369762702 DVT(ph)PPPETEVVLIK ddPTM_PC-9_AZD4547_30min_R2 11 DVTPPPETEVVLIK 14 0 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 DVT(1)PPPETEVVLIK;DVT(0.999)PPPET(0.001)EVVLIK;DVT(0.996)PPPET(0.004)EVVLIK;DVT(1)PPPETEVVLIK;DVT(1)PPPETEVVLIK;DVT(1)PPPETEVVLIK;DVT(1)PPPETEVVLIK;DVT(1)PPPETEVVLIK;DVT(1)PPPETEVVLIK;DVT(1)PPPETEVVLIK;DVT(0.999)PPPET(0.001)EVVLIK 220.99 1.4353e-15 92737800.0 370943.89999999997 445077.0 433015.0 379158.9 408569.7 518064.49999999994 481802.7 558854.2999999999 509354.1 403513.69999999995 True False 488896.34408756666 588939.4362948898 427272.9381730253 291749.67355160957 351846.84958137706 485669.844917821 524682.2069244946 472496.20912924514 536277.5178589949 389386.80818301043 1.255554461048375 1.5124791696027111 1.097296901676773 0.7492541283383392 0.9035921150569906 1.2472683581246489 1.347457581762492 1.2134366116151876 1.3772359684228088 1.0 18.570844483067873 -6.956067102031375 24.99474857543051 1.2587544897064757 1.1032209193844045 0.08648809137644498 0.21137425608305455 349.9329638977532 199086.28910716492 0.08326110821327798 0.07342936087935067 1.1064528148066773e-07 6.956067102031375 -0.15553357032207127 DVT(ph)PPPETEVVLIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 11 DVTPPPETEVVLIK 14 0 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 DVT(1)PPPETEVVLIK;DVT(1)PPPETEVVLIK;DVT(0.993)PPPET(0.007)EVVLIK;DVT(1)PPPETEVVLIK;DVT(1)PPPETEVVLIK;DVT(0.998)PPPET(0.002)EVVLIK;DVT(1)PPPETEVVLIK;DVT(0.997)PPPET(0.003)EVVLIK;DVT(1)PPPETEVVLIK;DVT(0.997)PPPET(0.003)EVVLIK;DVT(1)PPPETEVVLIK 205.62 2.2959e-10 101494240.0 336363.69999999995 565884.0 429987.60000000003 374556.4 411331.4 307386.10000000003 377807.30000000005 235517.96999999997 257666.10000000003 276011.5 True False 393303.4309240976 622061.2237229301 440240.13512105326 353571.2192362324 330733.9649371608 291266.2317936976 342018.65745601756 229335.87283941646 261433.97925613102 326050.2000441676 1.2062664916961245 1.9078694742057023 1.350221944539268 1.0844073065691626 1.0143651649112888 0.8933171387542223 1.0489754565698375 0.7033759611506144 0.801821250901599 1.0 18.314734579320117 -5.79965899859781 1.9839844678767393 0.9014988706996652 1.5716909221600222 0.6611213812583594 0.18734046735821763 0.18087162484567992 1.4541240236513984 0.05631245628696249 0.10740603635555765 1.586138115102054e-06 5.79965899859781 0.670192051460357 DVT(ph)PPPETEVVLIK ddPTM_PC-9_Lapatinib_30min_R1 15 DVTPPPETEVVLIK 14 0 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 DVT(1)PPPETEVVLIK;DVT(0.999)PPPET(0.001)EVVLIK;DVT(0.999)PPPET(0.001)EVVLIK;DVT(1)PPPETEVVLIK;DVT(1)PPPETEVVLIK;DVT(1)PPPETEVVLIK;DVT(0.997)PPPET(0.003)EVVLIK;DVT(0.985)PPPET(0.015)EVVLIK;DVT(1)PPPETEVVLIK;DVT(1)PPPETEVVLIK;DVT(0.998)PPPET(0.002)EVVLIK;DVT(1)PPPETEVVLIK;DVT(1)PPPETEVVLIK;DVT(0.994)PPPET(0.006)EVVLIK;DVT(0.995)PPPET(0.005)EVVLIK 207.52 1.0709000000000001e-36 84055900.0 398700.39999999997 569939.6 495180.39999999997 469087.0 589447.2000000001 577730.1000000001 567418.6999999998 605738.3999999999 512925.4000000001 495296.60000000003 True False 393014.85918330203 568619.9398731847 454468.57896361966 503585.22280836 554777.0745937836 553021.9303776412 596796.8638849773 633883.2174207465 455154.3401080857 580907.9573687665 0.6765527209568107 0.9788468769626764 0.7823418033764653 0.8668933114453428 0.9550171719228235 0.951995791007175 1.0273518486270696 1.0911938963479384 0.7835223021728189 1.0 19.147950066694733 -6.243492838843856 2.244292655934252 0.9794232153912942 0.8270195387358932 0.3268691451534049 0.10110572202772418 0.3789238129363751 3.749837403352008 0.032565205947801636 0.042303171858381686 5.708304886160239e-07 6.243492838843856 -0.152403676655401 DVTGS(ph)PPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DVTGSPPAK 9 0 O75362 O75362 ZNF217 Zinc finger protein 217 1 DVT(0.005)GS(0.995)PPAK;DVT(0.095)GS(0.905)PPAK;DVT(0.115)GS(0.885)PPAK 91.31299999999999 0.0078972 27800400.0 266228.0 305748.0 299626.0 341922.0 353834.0 298931.0 351626.0 314178.0 292753.0 243058.0 True False 311295.14215731627 336100.64082186203 306770.22017793293 322765.21886608 284502.7677186222 283254.5321220504 318317.4397282148 305931.1603991069 297033.9587907364 287122.4913539312 1.0841893321884974 1.1705827684796601 1.0684297796781872 1.1241377063290128 0.9908759372247168 0.9865285397405081 1.1086468295367016 1.0655074736795545 1.0345199966399967 1.0 18.131306820982793 -6.244999038525871 24.94029561596047 1.0359459579318586 1.1129308133697056 0.4606007482211517 0.042641051183937656 812.9192646768747 1233213.0403320545 0.013081961728698592 0.01683421757760796 5.688541902150843e-07 6.244999038525871 0.07698485543784694 DVTGS(ph)PPAK ddPTM_PC-9_Lapatinib_30min_R1 2 DVTGSPPAK 9 0 O75362 O75362 ZNF217 Zinc finger protein 217 1 DVT(0.158)GS(0.842)PPAK;DVT(0.021)GS(0.979)PPAK 97.734 0.0046885 36850000.0 429190.0 363300.0 402690.0 377580.0 425690.0 370250.0 318070.0 321030.0 384110.0 314280.0 True False 423069.6718961934 362458.8011710857 369582.3826283527 405348.4927699558 400651.7511387409 354415.2705949054 334538.1082715375 335946.2257776343 340847.4869423837 368602.8792482232 1.1477655105653457 0.9833314430704704 1.0026573405561214 1.0996888944456331 1.0869468842888106 0.9615097725708116 0.9075840887456934 0.9114042366212843 0.9247010973911883 1.0 18.491707814697108 -6.8865860718922525 4.775809064041436 0.9293379564869607 1.0577747851276853 0.5997404944278468 0.0502529474873774 0.15178520069390272 5.701557561212721 0.018334877246142668 0.01613867518210861 1.2984162080031125e-07 6.8865860718922525 0.1284368286407246 DVTNFTVGGFAPMS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 10 DVTNFTVGGFAPMSPR 16 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 DVTNFTVGGFAPMS(1)PR;DVTNFTVGGFAPMS(1)PR;DVTNFT(0.005)VGGFAPMS(0.995)PR;DVTNFTVGGFAPMS(1)PR;DVTNFTVGGFAPMS(1)PR;DVTNFTVGGFAPMS(1)PR;DVTNFTVGGFAPMS(1)PR;DVTNFTVGGFAPMS(1)PR;DVTNFTVGGFAPMS(1)PR;DVTNFTVGGFAPMS(1)PR 176.44 3.073e-10 344646300.0 254256.80000000002 245648.1 348969.9 419552.3 371028.5 363239.8 291771.5 386310.6 291271.1 340849.4 True False 335105.17353002285 325049.0444145868 344342.3311131177 322830.99925341876 319517.59719309554 340526.3578839707 317738.59826370905 326615.1733044636 306667.0957042641 328916.36625248264 1.0188157474438033 0.9882422334833676 1.0468993532805655 0.9814987406421952 0.971425048967699 1.0352977012477877 0.9660163824739773 0.9930037140619127 0.9323558423020534 1.0 18.327361270156047 -7.2934163049818865 24.86191259400097 0.9722609548162031 1.005209181570646 0.26676126396347255 0.02766060069908275 902.7678211159958 701894.1164143018 0.011250710229081843 0.007586059200685038 5.088428718000289e-08 7.2934163049818865 0.03294822675444298 DVTNFTVGGFAPMS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 DVTNFTVGGFAPMSPR 16 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 DVTNFT(0.004)VGGFAPMS(0.996)PR;DVTNFT(0.008)VGGFAPMS(0.992)PR;DVTNFTVGGFAPMS(1)PR;DVTNFTVGGFAPMS(1)PR;DVTNFT(0.011)VGGFAPMS(0.989)PR;DVTNFT(0.076)VGGFAPMS(0.924)PR;DVTNFTVGGFAPMS(1)PR 163.45 6.466100000000001e-05 306767500.0 250794.8 242937.6 274176.0 291152.6 305610.0 289015.0 317338.1 270566.0 245269.1 221964.6 True False 293249.4062169105 267054.8394093339 280713.3956582701 274840.26375146565 245727.9143397418 273858.5446181702 287277.53783911443 263463.9291883737 248855.69658395 262205.02490919345 1.1183973545833774 1.0184962683374204 1.0705873991373218 1.0481883932111828 0.9371594401169162 1.0444443035102495 1.0956217865718023 1.004801221027767 0.9490882055755164 1.0 18.000335808135723 -1.5228787452803798 0.607539784699572 1.012797545938353 7.074628815411686 0.2891366961176617 0.047036398187425846 270.80094021550696 2.0429785806621785 0.022121987919302418 2183.936092079169 0.02999999999999708 1.5228787452803798 6.061831269473333 DVTNFTVGGFAPMS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 10 DVTNFTVGGFAPMSPR 16 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 DVTNFTVGGFAPMS(1)PR;DVTNFT(0.017)VGGFAPMS(0.983)PR;DVTNFT(0.005)VGGFAPMS(0.995)PR;DVTNFTVGGFAPMS(1)PR;DVTNFTVGGFAPMS(1)PR;DVTNFTVGGFAPMS(1)PR;DVTNFTVGGFAPMS(1)PR;DVTNFTVGGFAPMS(1)PR;DVTNFTVGGFAPMS(1)PR;DVTNFTVGGFAPMS(1)PR 203.93 7.4179e-17 249667700.0 369316.5 307752.6 338279.5 276181.1 295051.6 316793.9 280871.4 261886.6 337813.3 248195.1 True False 364049.97898564773 307040.01776296337 310467.4653066318 296492.3794071412 277697.2449817645 303245.3633796499 295413.54677768506 274054.8075000378 299765.2088222476 291095.29233581666 1.250621320820497 1.054774934005983 1.0665492485823742 1.01854061956144 0.953973672172631 1.0417391533416367 1.0148345045610931 0.9414608024092659 1.0297837742989984 1.0 18.151131982469494 -1.5228787592430941 0.8695965246244067 0.9982678603880826 101.1913083312907 0.8248203233546842 0.03377512073645689 287.0249586410246 0.7269160928829217 0.011285171243086284 56968.89206347611 0.029999999035486963 1.5228787592430941 100.19304047090262 DVTNNVHYENYR ddPTM_PC-9_AZD4547_30min_R2 3 DVTNNVHYENYR 12 0 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181 G3V1Q4 SEPT7 Septin-7 0 ;; 103.97 0.0016499000000000002 21080700.0 91847.0 101071.0 123321.0 148831.0 131033.0 126517.0 112784.0 143840.0 120068.0 115734.0 False True 121052.43546372022 133740.2241988708 121685.68296349012 114520.31236602819 112841.3297442191 118605.87198981582 122821.55750844126 121612.83311437482 126414.54935631974 111682.18788668809 1.0839010029651202 1.1975072008310101 1.0895710879782505 1.0254125078765437 1.0103789322134973 1.0619945242311375 1.0997416851562318 1.088918791936296 1.1319132598349433 1.0 16.769039584191184 -5.510908509982364 23.885220632986776 1.06273448121525 1.1414128828647099 0.32428576943532506 0.046222547958857156 355.504546723918 709366.0687150626 0.012583589232174097 0.02410173761251586 3.083837533990043e-06 5.510908509982364 0.07867840164945994 DVTNNVHYENYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DVTNNVHYENYR 12 0 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181 G3V1Q4 SEPT7 Septin-7 0 ; 89.663 0.0061848 10367400.0 57342.0 53708.0 53790.0 63051.0 64937.0 56729.0 65266.0 48758.0 60073.0 40352.0 False True 67048.86804387526 59039.77529619349 55072.55759971098 59518.456884100066 52213.0610041549 53754.031374303006 59083.531995079175 47478.15416337129 60951.45397804954 47667.49817374375 1.4065950723800977 1.2385750785786747 1.155348187122732 1.248617174477264 1.0953597945049054 1.1276872803010216 1.239493035269546 0.9960278173257108 1.2786795261602983 1.0 15.540718287167017 -1.5228787469502973 0.642497749134057 1.1311563084782357 23.77050128057221 0.4598760241559948 0.08985936838442332 185.29615805605576 1.230332230657815 0.03531061729191134 5956.324850570473 0.029999999884643264 1.5228787469502973 22.639344972093973 DVTNNVHYENYR ddPTM_PC-9_Lapatinib_30min_R1 4 DVTNNVHYENYR 12 0 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181 G3V1Q4 SEPT7 Septin-7 0 ;;; 119.21 0.00046088 25715800.0 157550.0 146344.0 159017.0 144030.0 165193.0 164532.0 142416.0 136923.0 168496.0 132025.0 False True 155303.30810886875 146005.14945934882 145943.23608337072 154622.44666999523 155476.6725219338 157495.3499028249 149789.60363316027 143284.9424419869 149518.20613846005 154845.34533774553 1.002957549483482 0.9429095149155782 0.9425096748309889 0.998560507793992 1.0040771466705132 1.0171138793955947 0.9673497340617002 0.9253422641116961 0.965597033687606 1.0 17.240468490584156 -4.313198023146231 15.217365153172507 0.9732701704120799 47.06872431679181 0.08297226301122762 0.02912802077994554 115.43940921652468 8377.972257129655 0.007752648004213504 1.834897623684005 4.861854715149641e-05 4.313198023146231 46.09545414637973 DVTS(ph)PINER ddPTM_PC-9_Lapatinib_30min_R1 1 DVTSPINER 9 0 K7EJY2;K7ERF3;K7ELU8;D3DUE4;F6WF08;Q6ZW76-2;Q6ZW76 K7EJY2 ANKS3 Ankyrin repeat and SAM domain-containing protein 3 1 DVT(0.226)S(0.774)PINER 113.67 0.0020857 5531300.0 66221.0 62354.0 91869.0 73980.0 66997.0 62743.0 64848.0 68977.0 73113.0 68901.0 True False 65276.67639655582 62209.62314401838 84315.88544459516 79420.73599004529 63056.36818116989 60059.628151076664 68205.51213629905 72181.92323291865 64878.24402597824 80810.44604518828 0.8077752269806041 0.7698215538772236 1.0433785428859863 0.9828028414251558 0.7802997170181376 0.743216144574824 0.8440185084259937 0.8932251554774904 0.8028447707082209 1.0 16.30225417603517 -10.98199477886118 2.9311409798305563 1.0037705082128274 0.8546738186439657 0.1903040334022036 0.09146923889621841 56793167.84031558 66503582.71511615 1759574.4852151994 0.025796658270291935 1.0423299603301054e-11 10.98199477886118 -0.14909668956886168 DVVAS(ph)PKLPER ddPTM_PC-9_AZD4547_30min_R2 1 DVVASPKLPER 11 1 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 DVVAS(1)PKLPER 65.295 0.021256 10108000.0 35681.0 33339.0 54586.0 57304.0 65825.0 62948.0 57963.0 58730.0 54982.0 60303.0 True False 47026.815789094915 44115.179770321454 53862.15397414123 44093.448137974505 56686.334972207165 59011.851608992714 63121.59471079034 49654.62798114038 57888.23627202234 58191.81032480468 0.8081346073718795 0.7580994563339274 0.9255968094737567 0.7577260080389585 0.974129085446998 1.014092039405732 1.084716119991275 0.8532923740297307 0.9947832168979122 1.0 15.828528508023846 -6.308132979831644 8.633442157892322 0.9860291821871102 0.8166748922976208 0.6062188014371981 0.06884448419498837 0.2746860649652103 48.3657360999202 0.021470576742620175 0.024429804209923585 4.918888975294275e-07 6.308132979831644 -0.16935428988948942 DVVICPDASLEDAKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DVVICPDASLEDAKK 15 1 Q99497;K7ELW0;K7EN27 Q99497 PARK7 Protein deglycase DJ-1 0 ; 162.94 7.674e-15 3223800.0 37494.0 34398.0 36224.0 48882.0 50317.0 38872.0 40151.0 35608.0 36553.0 31963.0 False True 43840.99365974434 37812.806111537626 37087.71754028501 46143.30001758225 40457.74505360676 36833.483889754934 36347.60661193306 34673.32772979461 37087.51847351798 37757.638881031235 1.1611158684440215 1.0014610879319075 0.9822573296265413 1.2220917775863316 1.071511520651044 0.975524025901403 0.9626557085960544 0.9183129230894221 0.9822520574015577 1.0 15.204480930236192 -6.767295968574013 4.557758500840834 0.9608350922683055 1.085527348657121 0.43961746575327654 0.06779254278932147 0.19806078822670153 10.145630227248931 0.02466416366867478 0.022954012669463685 1.7088503489229503e-07 6.767295968574013 0.12469225638881554 DVVICPDASLEDAKK ddPTM_PC-9_Lapatinib_30min_R1 3 DVVICPDASLEDAKK 15 1 Q99497;K7ELW0;K7EN27 Q99497 PARK7 Protein deglycase DJ-1 0 ;; 175.29 7.4075e-06 16760000.0 113789.0 106055.0 112208.0 109877.0 105071.0 91851.0 110023.0 94787.0 114067.0 107414.0 False True 112166.34799365315 105809.43616349969 102982.69137540588 117957.72111892674 98890.93035753409 87922.74684513868 115719.45259332652 99191.15005695607 101219.57328123927 125980.36677984153 0.8903478443563414 0.8398883005985227 0.8174503218852703 0.9363182862061764 0.7849709671853242 0.6979083256583076 0.9185514818793425 0.7873540345401497 0.80345514041983 1.0 16.942839391048047 -11.107541186027282 2.8135539284340654 1.0115284656213135 0.8297404650224769 0.36408463653419654 0.06711561582928466 48878465.066685796 49125504.841309674 4198984.79181409 0.017099559898476443 7.80654403788104e-12 11.107541186027282 -0.1817880005988366 DVVLST(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DVVLSTSPK 9 0 A0A075B784;Q9P275 A0A075B784 USP36 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 36 1 DVVLS(0.088)T(0.853)S(0.059)PK 109.66 0.0057548 4095600.0 54111.0 48019.0 42258.0 53054.0 52373.0 45305.0 60076.0 59297.0 43080.0 38794.0 True False 63270.92355903417 52786.008973484684 43265.59098435745 50081.55638338874 42110.88661272624 42929.126045105644 54385.16636742527 57740.51658036487 43709.963500647114 45827.04510686499 1.3806459354185165 1.151852772754428 0.9441060597179146 1.0928384377959035 0.9189090528208186 0.9367639991842888 1.186748267111777 1.259965953417215 0.953802790442172 1.0 15.48391164437782 -4.842951895787633 3.2155277911598876 1.045313906569892 1.406588550589609 0.48085337446814524 0.10848350008571163 0.2768664020509814 4.650694621502565 0.029450624918364834 0.23250905964800966 1.4356484427720837e-05 4.842951895787633 0.361274644019717 DVVLSTS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 DVVLSTSPK 9 0 A0A075B784;Q9P275 A0A075B784 USP36 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 36 1 DVVLST(0.001)S(0.999)PK;DVVLS(0.006)T(0.033)S(0.961)PK 144.77 0.00053041 47486000.0 565500.0 462920.0 432240.0 520940.0 475360.0 468120.0 500130.0 512610.0 446780.0 464760.0 True False 745317.23686929 612549.837106008 426508.21517940063 400845.3314427693 409364.4693108752 438848.3823981966 544640.6011198105 433397.90310594835 470395.8786805525 448488.8938619346 1.6618410111594262 1.3658082630125927 0.9509894693416854 0.8937686906605269 0.9127638942981191 0.9785044588713812 1.214390386414955 0.9663514727732991 1.0488462147411879 1.0 18.77471273389863 -5.026715138919699 2.7336066073230927 0.9950212669589034 1.6610635421004254 0.8612835413630144 0.08690326042966263 0.1102915693699109 1.499957555053182 0.025302753582775502 0.12878553373012805 9.40339893135169e-06 5.026715138919699 0.666042275141522 DVVLSTS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DVVLSTSPK 9 0 A0A075B784;Q9P275 A0A075B784 USP36 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 36 1 DVVLS(0.003)T(0.018)S(0.979)PK;DVVLS(0.006)T(0.032)S(0.962)PK;DVVLS(0.004)T(0.126)S(0.87)PK;DVVLS(0.01)T(0.04)S(0.95)PK 112.85 0.0021408 37474400.0 463299.0 449356.0 365329.0 462239.0 443289.0 372218.0 500918.0 464766.0 384159.0 360449.0 True False 541726.3701276445 493965.0939896537 374039.82887794834 436341.2474290587 356429.7026267118 352698.23282766 453467.4207077365 452566.3849602816 389776.5986175744 425795.5503872857 1.2722687440836642 1.160099239037054 0.8784493603508479 1.0247670437893988 0.8370911868442926 0.8283276622004634 1.0649886319743869 1.062872508997913 0.9154078718367301 1.0 18.69980134797587 -5.085167105209979 3.8980009964872453 0.9524229888443544 1.2546105866315589 0.6286504024999731 0.08317530020925937 0.1453422502320237 3.985127207028464 0.022847472674611655 0.07567788699154102 8.21926333241201e-06 5.085167105209979 0.3021875977872045 DVVMLDNLPDLPPALVPS(ph)PPKR ddPTM_PC-9_AZD4547_30min_R2 2 DVVMLDNLPDLPPALVPSPPKR 22 1 H3BPM3;H3BRE8;Q9BWH6-2;Q9BWH6;H3BPY8 H3BPM3 RPAP1 RNA polymerase II-associated protein 1 1 DVVMLDNLPDLPPALVPS(1)PPKR;DVVMLDNLPDLPPALVPS(1)PPKR 78.752 0.00096269 44822000.0 49785.6 46260.2 48342.3 55116.3 63816.5 56753.1 54345.4 48773.1 48384.7 59343.6 True False 65616.38519518971 61212.90498248369 47701.24951570231 42410.08857334641 54956.680527973454 53204.31968530098 59182.03531901012 41236.33808934034 50942.21646267721 57265.99862678608 1.1458175316704902 1.068922335248537 0.8329768214919442 0.7405806166018584 0.9596738351868634 0.9290734635057031 1.033458539764778 0.7200841525192945 0.8895717822835463 1.0 15.805391180446206 -5.127842363432491 4.236605089073464 0.882570149959122 1.1293840338251675 0.45413319544202224 0.09726561846833907 0.19575965533143627 5.667640260117354 0.025686371970973745 0.07796182630137452 7.450023395344727e-06 5.127842363432491 0.24681388386604552 DVWS(ph)APSSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DVWSAPSSLR 10 0 V9GZ20;V9GXZ5;Q70EL4-2;Q70EL4-3;Q70EL4-4;Q70EL4 V9GZ20 USP43 Ubiquitin carboxyl-terminal hydrolase 43 1 DVWS(0.953)APS(0.02)S(0.027)LR;DVWS(0.458)APS(0.458)S(0.085)LR;DVWS(0.959)APS(0.035)S(0.007)LR 92.11200000000001 0.0076408000000000005 10764100.0 25800.9 34400.6 33213.8 41907.0 45127.0 37664.0 40723.0 33307.9 36693.2 30757.5 True False 30168.482778996575 37815.66422235484 34005.74295603795 39559.08665432713 36284.68829688001 35688.833536317405 36865.422631011694 32433.602917637232 37229.76863328566 36333.59127376397 0.8303193194332227 1.0407907090004906 0.9359312350880403 1.0887744719826873 0.9986540560630112 0.9822545001789533 1.0146374563758511 0.8926616329571895 1.0246652568079284 1.0 15.149016350774533 -4.751551419111555 24.90131582975069 0.9952506654848639 0.8303189689305135 0.4885886938220525 0.05129134189906381 333.46130251494475 839710.2275645833 0.012363383691833596 0.16113602641956373 1.7719382407564335e-05 4.751551419111555 -0.16493169655435036 DVWS(ph)APSSLR ddPTM_PC-9_Lapatinib_30min_R1 3 DVWSAPSSLR 10 0 V9GZ20;V9GXZ5;Q70EL4-2;Q70EL4-3;Q70EL4-4;Q70EL4 V9GZ20 USP43 Ubiquitin carboxyl-terminal hydrolase 43 1 DVWS(0.483)APS(0.483)S(0.033)LR;DVWS(0.96)APS(0.033)S(0.007)LR;DVWS(0.952)APS(0.04)S(0.009)LR 93.839 0.0065373 11430000.0 46147.0 53009.0 44298.0 35384.0 44645.0 42747.0 39681.4 33153.2 37378.8 32665.399999999998 True False 45488.93531767665 52886.26091736327 40655.98943522498 37986.25739756378 42019.06887544711 40918.81045812401 41735.90872941863 34693.61870370699 33168.80592778622 38311.57086609044 1.1873419515131105 1.3804252794075036 1.0611934858356222 0.991508741062492 1.0967722785973826 1.0680535810224696 1.0893812961963163 0.9055650269463187 0.8657647070573115 1.0 15.22549256047325 -4.784108410754696 0.39112381820127406 0.9432103388709836 1.5440318915094364 0.5481998310435208 0.09285238965648587 4.56006295046201 0.5531231865789733 0.08345817906617861 1.298923860178858 1.6439612981720826e-05 4.784108410754696 0.6008215526384528 DVWSAPS(ph)SLR ddPTM_PC-9_Lapatinib_30min_R1 1 DVWSAPSSLR 10 0 V9GZ20;V9GXZ5;Q70EL4-2;Q70EL4-3;Q70EL4-4;Q70EL4 V9GZ20 USP43 Ubiquitin carboxyl-terminal hydrolase 43 1 DVWS(0.151)APS(0.523)S(0.326)LR 105.13 0.0025043 5010400.0 14272.0 14232.0 12823.0 10725.0 13262.0 11209.0 7883.7 8714.3 11937.0 7845.2 True False 14068.478662835743 14199.046678411472 11768.742438211426 11513.75227755119 12481.955234095194 10729.617199455204 8291.879410759644 9119.198191116206 10592.529357817373 9201.232366928085 1.5289776523199177 1.5431679270971344 1.279039803462819 1.251327193837097 1.3565525503908569 1.1661065356876086 0.9011705258703258 0.9910844360254683 1.1512076790811214 1.0 13.167611386112922 -5.8167176044148565 0.49351244445793174 0.9879754411548403 1.666176508129134 0.7830855799402089 0.09691564943067069 0.8894377625239772 0.337197208993219 0.0813016394784303 0.3168232313202115 1.5250440759173357e-06 5.8167176044148565 0.6782010669742937 DVWSAPSS(ph)LR ddPTM_PC-9_AZD4547_30min_R2 1 DVWSAPSSLR 10 0 V9GZ20;V9GXZ5;Q70EL4-2;Q70EL4-3;Q70EL4-4;Q70EL4 V9GZ20 USP43 Ubiquitin carboxyl-terminal hydrolase 43 1 DVWS(0.027)APS(0.356)S(0.617)LR 101.28 0.0036613 4503000.0 5113.6 7297.5 12562.0 16408.0 13121.0 10273.0 12653.0 11612.0 7985.1 15143.0 True False 6739.618430512484 9656.274164609637 12395.41967213501 12625.38910107297 11299.375634946135 9630.627686013568 13779.092487891068 9817.632217214405 8407.176084095256 14612.848179170476 0.46121182865085175 0.6608071230339568 0.8482548727087821 0.8639923542810442 0.7732493690759444 0.6590520593884844 0.9429436560856176 0.6718493271700932 0.5753276829413075 1.0 13.834949779695823 -14.522878710204544 0.030144860357933265 2.014967157934426 1.5903273953097187e-11 0.22575789866501084 0.1416004828269008 2857.8721147241013 6.460954663468069 337.9303312610764 135.95779413541217 3.000000242295005e-15 14.522878710204544 -2.0149671579185227 DVYHLNR ddPTM_PC-9_AZD4547_30min_R2 2 DVYHLNR 7 0 I3L2Z5;A0A087WWR2;P56270-3;P56270;P56270-2;J3QSH4;Q14119;Q9HBE1-4;Q9HBE1-2;Q9HBE1-3;Q9HBE1 I3L2Z5 MAZ;VEZF1;PATZ1 Myc-associated zinc finger protein;Vascular endothelial zinc finger 1;POZ-, AT hook-, and zinc finger-containing protein 1 0 ; 124.34 4.9633000000000004e-05 0.0 39912.0 43586.0 53410.0 66553.0 57223.0 54306.0 43438.0 61814.0 43738.0 55791.0 False True 52603.18577882786 57674.32212931494 52701.748502525916 51210.23408360002 49278.57419087897 50910.23723514583 47303.89784944377 52262.06664441021 46049.90138710326 53837.77407145876 0.9770683629863256 1.0712612682085247 0.9788990984763782 0.9511952335850435 0.9153159661740774 0.9456229963663204 0.8786376975143402 0.9707323073023576 0.8553455669616155 1.0 15.716331142349585 -5.6824111490693126 2.3692963338528963 0.9254904940680936 1.0245445666012232 0.40871180674951213 0.045023669033993095 0.2466025193912727 2.804448744218682 0.012137725674186183 0.024233603586984093 2.0777287580301475e-06 5.6824111490693126 0.09905407253312959 DVYHLNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DVYHLNR 7 0 I3L2Z5;A0A087WWR2;P56270-3;P56270;P56270-2;J3QSH4;Q14119;Q9HBE1-4;Q9HBE1-2;Q9HBE1-3;Q9HBE1 I3L2Z5 MAZ;VEZF1;PATZ1 Myc-associated zinc finger protein;Vascular endothelial zinc finger 1;POZ-, AT hook-, and zinc finger-containing protein 1 0 ; 107.66 0.0018133 0.0 27649.0 23578.5 28698.0 32546.5 33573.0 30658.5 31104.4 30811.0 28511.0 20608.7 False True 32329.42960735775 25919.21765512212 29382.269157771083 30723.025122176678 26994.611655797064 29050.714288795323 28157.966055645218 30002.243896952987 28927.91943748724 24344.89417162055 1.3279757709953395 1.064667501629019 1.2069171034648705 1.2619904981140264 1.1088407887706224 1.1932980313654624 1.1566271702454003 1.2323834182827276 1.1882540640168087 1.0 14.57133160870814 -10.457802910701417 4.069437531573428 0.9999918435653886 1.1896349278947984 0.40274184195894625 0.07053297962714386 13026506.287356915 27761607.921241798 1661.7159105416347 0.016456782205483512 3.4849543156825356e-11 10.457802910701417 0.1896430843294098 DVYHLNR ddPTM_PC-9_Lapatinib_30min_R1 2 DVYHLNR 7 0 I3L2Z5;A0A087WWR2;P56270-3;P56270;P56270-2;J3QSH4;Q14119;Q9HBE1-4;Q9HBE1-2;Q9HBE1-3;Q9HBE1 I3L2Z5 MAZ;VEZF1;PATZ1 Myc-associated zinc finger protein;Vascular endothelial zinc finger 1;POZ-, AT hook-, and zinc finger-containing protein 1 0 ; 116.54 0.00032762 2163500.0 56340.0 52184.0 54891.0 44665.0 48452.0 51358.0 47245.0 44964.0 51856.0 39053.0 False True 55536.581268509406 52063.171154175376 50378.07386538749 47949.813098072176 45602.14862029709 49161.538061345425 49691.11492843958 47053.1915891522 46015.431212111755 45803.259015148455 1.2125028319522386 1.1366695792750596 1.0998796799312034 1.0468646583033272 0.9956092557783967 1.0733196527584705 1.084881643727694 1.0272891624063336 1.0046322511001484 1.0 15.483162632843673 -4.988872981247584 1.0441579285374594 1.0347465508931033 1.2631372520701145 0.8038147822449444 0.02901427826468213 0.6245874642927758 0.7010837979338023 0.010315194350212959 0.14727191177859547 1.0259519440654255e-05 4.988872981247584 0.2283907011770112 DVYLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 DVYLSPR 7 0 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 DVYLS(1)PR;DVYLS(1)PR;DVYLS(1)PR;DVYLS(1)PR 90.601 0.015819 4899200000.0 400413.0 389515.0 514259.0 521027.0 511801.0 496882.0 412205.0 517700.0 426847.0 412841.0 True False 527736.0048922069 515418.10636901937 507439.5896491383 400912.274936905 440746.2654783213 465811.8899914133 448890.4464531048 437701.3605625129 449409.260994579 398387.5622490206 1.324679922016075 1.293760536747998 1.2737335141300228 1.0063373280873318 1.1063253656569314 1.1692430540797045 1.126768225190013 1.0986822934218974 1.1280705111814364 1.0 18.603813081276137 -5.652125457719274 6.571808997368255 1.1007022384737244 1.3023616803415554 0.7749505508479515 0.050980188793752865 0.10002148730086619 5.415156497382816 0.013943767242663694 0.024297127834547082 2.2277914984167994e-06 5.652125457719274 0.20165944186783102 DVYLS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 DVYLSPR 7 0 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 DVYLS(1)PR;DVY(0.008)LS(0.992)PR;DVYLS(1)PR;DVYLS(1)PR;DVYLS(1)PR;DVYLS(1)PR;DVYLS(1)PR 98.58200000000001 0.012116 4178301000.0 641452.0 666196.0 775436.0 715884.0 763526.0 650310.0 700892.0 613579.0 577607.0 529863.0 True False 750037.1543455038 732331.536144017 793925.335097406 675775.3404072417 613918.5613172502 616206.5987946728 634498.4357413525 597473.2013906885 586053.4096499148 625922.9675067987 1.1982898747637936 1.1700026587314238 1.2684074180242995 1.0796461793038479 0.9808212722447862 0.9844767340127675 1.0137005169641113 0.9545474961089343 0.9363027721834624 1.0 19.25562558968685 -6.002167233521279 3.383074630763618 0.9791899090233768 1.2074752659772263 0.9144919289904588 0.03192085710438506 0.06452426502785057 1.5571421573703583 0.009841911252546137 0.014352382161794897 9.950221909607416e-07 6.002167233521279 0.22828535695384955 DVYLS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 5 DVYLSPR 7 0 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 DVYLS(1)PR;DVYLS(1)PR;DVYLS(1)PR;DVYLS(1)PR;DVY(0.001)LS(0.999)PR 94.309 0.013489 4879000000.0 607848.0 570586.0 645493.0 543276.0 609425.0 565807.0 538386.0 494722.0 586312.0 495944.0 True False 599179.97605433 569264.8431736996 592423.0572150364 583230.3293556086 573579.8196756492 541608.7535705371 566260.99273707 517708.59019145335 520275.3684209276 581667.25959616 1.030107791300354 0.97867781585116 1.018491323761877 1.00268722320822 0.9860961060003174 0.9311315784673272 0.9735136083303256 0.8900425142561541 0.8944553090062941 1.0 19.149834575667178 -6.699724885281997 1.509207853670805 0.9285513135887664 1.0079116875054377 0.4826608341741556 0.03365027697008323 0.3189822944188587 1.5105536113156375 0.014387958235831793 0.01373246695717024 1.9965266642852906e-07 6.699724885281997 0.07936037391667128 DVYLS(ph)PRDDGYSTK ddPTM_PC-9_AZD4547_30min_R2 2 DVYLSPRDDGYSTK 14 1 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 DVY(0.008)LS(0.991)PRDDGYSTK;DVYLS(0.818)PRDDGY(0.065)S(0.089)T(0.029)K 93.51 0.017981999999999998 217309000.0 49560.0 22551.9 61567.0 192087.0 122106.0 58893.0 32268.0 52563.0 37006.0 74549.0 True False 65319.04908796124 29841.360648559104 60750.58135283679 147804.30986456614 105153.68960298243 55210.41140001921 35139.78948860104 44440.59612757844 38962.061610753684 71939.0622009495 0.9079774894132429 0.4148144239801508 0.8444728009261561 2.0545765449610673 1.4617050373725131 0.7674608162919659 0.48846604909088237 0.6177533424531059 0.5415981306778759 1.0 16.13448773214398 -6.9520108472694675 8.805317530117673 0.6296871524980167 1.1307368644585043 0.22652531127920728 0.4209711678365719 0.49529475415667396 84.04874636085484 0.1679097284818653 0.14785917819226682 1.1168353525025472e-07 6.9520108472694675 0.5010497119604876 DVYLS(ph)PRDDGYSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DVYLSPRDDGYSTK 14 1 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 DVY(0.144)LS(0.846)PRDDGY(0.007)S(0.002)T(0.001)K;DVYLS(0.999)PRDDGYS(0.001)TK 130.47 9.345200000000001e-05 29500600.0 53667.0 8606.6 25974.0 86651.0 83067.0 103255.0 65670.0 162422.0 99484.0 51647.0 True False 62751.76312843389 9461.006368962144 26593.318666943534 81796.22539633235 66790.61765144904 97840.12602996091 59449.26219037252 158158.59460033433 100938.76529476265 61010.19226257295 1.0285455724900137 0.155072554569969 0.4358832136193309 1.3406977156259627 1.0947452413196561 1.603668541296853 0.9744152572822167 2.5923307030349685 1.6544574201691888 1.0 15.896762656624329 -6.216929517289976 0.9916275619299434 1.677441192840918 0.48202642609050733 0.40706051116531417 0.49506885495528685 0.5025736656282027 1.038493822428546 0.2247565568430583 0.37004450409822726 6.068348062970995e-07 6.216929517289976 -1.1954147667504107 DVYLS(ph)PRDDGYSTK ddPTM_PC-9_Lapatinib_30min_R1 2 DVYLSPRDDGYSTK 14 1 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 DVY(0.463)LS(0.535)PRDDGYSTK;DVYLS(0.995)PRDDGYS(0.004)TK 100.41 0.0094809 10716300.0 118307.0 25291.0 61403.0 46372.0 33287.0 37337.0 20421.7 15966.0 51352.0 24540.3 True False 116619.92048515353 25232.44024337442 56354.682362434374 49782.35157245721 31329.12410475996 35740.18354679802 21479.035701854475 16707.838646748598 45568.196999466985 28782.058157105665 4.051827004468845 0.8766725473780992 1.9579795876592525 1.7296314009485465 1.088494920472721 1.2417521829645302 0.7462647592681543 0.5804949234536863 1.5832153750345053 1.0 14.812882140039147 -4.757328735679703 24.999891627854392 1.2111916211729354 4.0518311423943585 0.8068555897104153 0.41848584523494464 54.73093451947268 332815.0545451305 0.11125400965348092 0.8344254664289521 1.748522657560619e-05 4.757328735679703 2.840639521221423 DVYLSPR ddPTM_PC-9_AZD4547_30min_R2 1 DVYLSPR 7 0 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 0 90.777 0.026654 0.0 25864.0 19002.0 39404.0 63604.0 46779.0 34971.0 32958.0 40500.0 26942.0 34916.0 False True 34088.213995379934 25144.024895637176 38881.47721388377 48941.0804720042 40284.543314316354 32784.2578416802 35891.19815189392 34241.65559741504 28366.099116816873 33693.60146760328 1.0117117942454468 0.7462551879416451 1.1539721347766485 1.4525333695497502 1.1956140501350183 0.9730113853576198 1.065222967820868 1.0162658221721628 0.8418838557252821 1.0 15.04018702414904 -7.774614596771243 1.5897615145408615 0.9258184905648942 1.0976687642758025 0.12095339577675779 0.17305648237222285 0.9756900575914177 4.6392393562221415 0.15380244707112992 0.05966731465012545 1.680294489887325e-08 7.774614596771243 0.17185027371090833 DVYLSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DVYLSPR 7 0 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 0 ; 120.65 0.00068771 0.0 28982.0 31101.0 36106.0 34171.0 38994.0 33086.0 33797.0 27987.0 31827.0 24865.0 False True 33888.08017940767 34188.501740651576 36966.903972767504 32256.50965387674 31353.40562077117 31350.91191542581 30595.503490909374 27252.370904677668 32292.409664231585 29372.827668768303 1.1537220917766922 1.163949965123845 1.258540866056075 1.0981751575853425 1.067428916764074 1.0673440183888314 1.0416260850310004 0.9278088991634508 1.0993973759825524 1.0 14.842194537528922 -6.265164813501419 1.4269286707217255 1.0201919467898581 1.1886103931891316 0.6429476839459854 0.052027244723533025 0.25595380145656743 1.047166628049899 0.01974593628768845 0.027352702877759674 5.430442086747962e-07 6.265164813501419 0.1684184463992735 DVYLSPR ddPTM_PC-9_Lapatinib_30min_R1 1 DVYLSPR 7 0 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 0 115.46 0.0014732 0.0 10674.0 10676.0 10724.0 7662.9 8690.5 8975.3 9432.9 8273.6 10516.0 8969.7 False True 10521.786802628132 10651.280377931489 9842.314115837115 8226.45522868503 8179.34187618038 8591.44734144619 9921.289406465829 8658.021660261764 9331.57734161075 10520.10069362603 1.0001602749870184 1.0124694323871766 0.9355722347601125 0.781974951406056 0.7774965387105202 0.8166696870735866 0.9430793198088863 0.8229979838032851 0.8870235764249492 1.0 13.360860893067468 -5.532790213290193 5.065315715799553 0.8518847903386985 1.0005714974996007 0.4307394982787335 0.06651982247082157 0.14984765844915954 11.18373427262701 0.01808822410704101 0.03423874846302661 2.9323093603644896e-06 5.532790213290193 0.14868670716090227 DVYLSPRDDGYS(ph)TK ddPTM_PC-9_AZD4547_30min_R2 1 DVYLSPRDDGYSTK 14 1 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 DVYLS(0.152)PRDDGY(0.368)S(0.43)T(0.05)K 103.21 0.006125 11328000.0 17005.0 7247.1 19540.0 67297.0 39901.0 16022.0 9118.6 16190.0 10123.0 24267.0 True False 22412.23627402707 9589.583350235354 19280.886832790813 51782.7163782855 34361.4348913944 15020.141807194543 9930.137734931124 13688.207509188884 10658.081113485907 23417.419716299937 0.9570753970996557 0.4095064044806109 0.8233565895123002 2.211290441288098 1.4673450494409837 0.6414089164887632 0.42404918454867807 0.584530989110686 0.45513473485156175 1.0 14.515294498617497 -6.857744891183986 7.3311721475463845 0.5761541557143322 1.1681655740964008 0.26149459425425503 0.462129311738627 0.3526944091703311 23.290570015927827 0.18304856480368342 0.1616007957438656 1.3875706620731876e-07 6.857744891183986 0.5920114183820686 DVYLSPRDDGYS(ph)TK ddPTM_PC-9_Lapatinib_30min_R1 1 DVYLSPRDDGYSTK 14 1 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 DVYLS(0.042)PRDDGY(0.244)S(0.566)T(0.148)K 89.992 0.024645 8341900.0 57795.0 13978.0 37272.0 21528.0 18880.0 20201.0 9238.2 9862.5 30275.0 16335.0 True False 56970.83270169504 13945.63479980576 34207.640034080665 23111.240935302743 17769.515519508168 19337.050320831 9716.508793140243 10320.747754826387 26865.110690116515 19158.482984980663 2.973660949374617 0.7279091361637805 1.7855088036405504 1.2063189425499323 0.9275011770732903 1.0093205362862145 0.5071648314095392 0.5387038087993377 1.4022566771689324 1.0 14.225695709063418 -3.465039866272988 1.887320459449536 0.9944940811034025 199.98032941072756 0.685890628847958 0.38909618983861743 84.80028266230084 3.7516605958227416 0.10851629759368965 70854.32153214043 0.000342736323455042 3.465039866272988 198.98583532962417 DVYTGDALR ddPTM_PC-9_Lapatinib_30min_R1 1 DVYTGDALR 9 0 P20618 P20618 PSMB1 Proteasome subunit beta type-1 0 104.06 0.012572 6984000.0 36395.0 44934.0 52467.0 41045.0 42561.0 45525.0 46991.0 38384.0 54258.0 50240.0 False True 35876.00062597442 44829.95808373673 48153.36578847689 44063.58622210615 40057.64565814548 43578.00187395828 49423.96405127112 40167.46076768122 48146.89267793036 58923.91705940797 0.6088529482825065 0.7608108951504107 0.8172125715934321 0.7478047696265777 0.6798198025049619 0.7395638994947041 0.8387759422280284 0.6816834788356618 0.8171027161922713 1.0 15.846565718516983 -14.522878738923763 0.22712814300001882 2.3574290814983874 0.7158242971651664 0.6090209289284032 0.06421718801657385 111.84572489343284 1.116758711127867 69.58592696383565 0.11503801785131669 3.0000000439096588e-15 14.522878738923763 -1.641604784333221 DWEDDS(ph)DEDMSNFDR ddPTM_PC-9_AZD4547_30min_R2 23 DWEDDSDEDMSNFDR 15 0 A0A087WYT3;Q15185-4;Q15185;B4DDC6;Q15185-2 A0A087WYT3 PTGES3 Prostaglandin E synthase 3 1 DWEDDS(0.986)DEDMS(0.014)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.993)DEDMS(0.007)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.997)DEDMS(0.003)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.998)DEDMS(0.002)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.986)DEDMS(0.014)NFDR;DWEDDS(0.925)DEDMS(0.075)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.762)DEDMS(0.238)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.981)DEDMS(0.019)NFDR 325.08 1.1947999999999998e-159 1807868000.0 3318880.1999999997 4000568.6999999997 4062587.4 2812880.3000000003 3490134.0 4737859.9 4323045.7 5150768.0 4405648.5 3441816.5999999996 True False 4374215.066603355 5293674.296890161 4008714.8366285493 2164414.2054024176 3005589.1381980893 4441600.771477994 4707788.392450795 4354835.158473744 4638522.08540033 3321319.6484414344 1.3170111671293077 1.5938466806030775 1.2069644782638378 0.6516729596978396 0.9049382342974712 1.3373000016912746 1.4174451395125356 1.3111761647263604 1.39659008357627 1.0 21.663325145832204 DWEDDS(ph)DEDMSNFDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 19 DWEDDSDEDMSNFDR 15 0 A0A087WYT3;Q15185-4;Q15185;B4DDC6;Q15185-2 A0A087WYT3 PTGES3 Prostaglandin E synthase 3 1 DWEDDS(0.998)DEDMS(0.002)NFDR;DWEDDS(0.999)DEDMS(0.001)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.998)DEDMS(0.002)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.906)DEDMS(0.094)NFDR;DWEDDS(0.995)DEDMS(0.005)NFDR;DWEDDS(0.992)DEDMS(0.008)NFDR;DWEDDS(0.999)DEDMS(0.001)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.999)DEDMS(0.001)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.999)DEDMS(0.001)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.985)DEDMS(0.015)NFDR;DWEDDS(0.993)DEDMS(0.007)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.994)DEDMS(0.006)NFDR 323.91 1.3973999999999994e-159 856798400.0 1521757.3 2299962.1999999997 1852859.7 1610419.1 1780006.0999999999 1437263.0000000002 1894932.4 1201090.9 1341774.0 1346536.0 True False 1779360.754813294 2528287.2472953545 1897038.9022575465 1520192.5388761696 1431226.6825857004 1361890.3981230932 1715430.6849494718 1169563.5365359997 1361394.9063629813 1590652.3176268856 1.118635879818127 1.5894656671844782 1.1926169416379835 0.9557038467992579 0.8997734242269647 0.8561835814346374 1.0784447776172386 0.7352728962674171 0.8558720791945682 1.0 20.601187097355833 -5.66932398671417 3.096134511058797 0.9007961751908524 1.3619373002718844 0.6384581888520957 0.1371654556814463 0.13803429010648768 2.633059819796937 0.03710982648439176 0.06931246821745446 2.1412925859170832e-06 5.66932398671417 0.461141125081032 DWEDDS(ph)DEDMSNFDR ddPTM_PC-9_Lapatinib_30min_R1 28 DWEDDSDEDMSNFDR 15 0 A0A087WYT3;Q15185-4;Q15185;B4DDC6;Q15185-2 A0A087WYT3 PTGES3 Prostaglandin E synthase 3 1 DWEDDS(0.997)DEDMS(0.003)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.998)DEDMS(0.002)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.999)DEDMS(0.001)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.998)DEDMS(0.002)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.999)DEDMS(0.001)NFDR;DWEDDS(0.998)DEDMS(0.002)NFDR;DWEDDS(0.999)DEDMS(0.001)NFDR;DWEDDS(0.998)DEDMS(0.002)NFDR;DWEDDS(0.999)DEDMS(0.001)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.979)DEDMS(0.021)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.999)DEDMS(0.001)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.827)DEDMS(0.173)NFDR 366.69 3.1247999999999987e-258 1872639000.0 1954296.7200000004 3302365.6 2776875.1 2549037.6000000006 3089353.8000000007 2848632.6000000006 3138351.3000000003 3325071.63 3002665.9999999995 2853414.74 True False 1926428.0903986746 3294719.175349936 2548571.1483258726 2736502.3284441624 2907644.08338726 2726803.224184926 3300839.774243158 3479566.596700581 2664474.135605268 3346623.6758728563 0.5756333179278753 0.9844904878618052 0.7615350260919796 0.8176904825519219 0.8688291140559439 0.8147923065994952 0.986319375566553 1.0397244906220449 0.7961678376969972 1.0 21.674274900009124 -7.254042561420015 23.395314860190737 0.9588633028456485 0.8137025890313286 0.30060944984704496 0.11272860195043327 304.0309845914598 961618.6264249656 0.041249771072629664 0.031236454550161205 5.571311466846507e-08 7.254042561420015 -0.14516071381431983 DWEDDSDEDMS(ph)NFDR ddPTM_PC-9_Lapatinib_30min_R1 1 DWEDDSDEDMSNFDR 15 0 A0A087WYT3;Q15185-4;Q15185;B4DDC6;Q15185-2 A0A087WYT3 PTGES3 Prostaglandin E synthase 3 1 DWEDDS(0.345)DEDMS(0.655)NFDR 69.346 0.022844999999999997 9304800.0 59465.0 23282.0 23269.0 23508.0 28996.0 19773.0 17813.0 17345.0 24930.0 18649.0 True False 58617.01819545457 23228.09195944181 21355.912640937513 25236.856740389136 27290.512288329384 18927.35488311426 18735.26998032162 18150.912021035616 22122.120875461762 21872.454801769487 2.6799469344754314 1.061979195749105 0.976383896297265 1.1538191286305672 1.2477114496595771 0.8653511942145166 0.8565691482789546 0.829852533039282 1.0114146343405441 1.0 14.416827526391526 -4.761244987155048 5.7876266190470655 0.9935775442297701 2.750350985128955 0.9432748160649532 0.12366914126301062 0.0331689631570289 3.937166649286509 0.03473553830792141 0.23229893871511392 1.7328262281881812e-05 4.761244987155048 1.7567734408991849 up DWEDDSDEDMSNFDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DWEDDSDEDMSNFDR 15 0 A0A087WYT3;Q15185-4;Q15185;B4DDC6;Q15185-2 A0A087WYT3 PTGES3 Prostaglandin E synthase 3 0 187.78 4.5600999999999996e-38 0.0 14473.0 14351.0 13590.0 14009.0 10075.0 8133.1 13160.0 9628.2 11980.0 5991.0 False True 16922.993045220042 15775.672437545109 13914.037140362012 13224.121147790795 8100.876073992655 7706.58591849573 11913.38952985079 9375.469951921154 12155.184836066679 7077.12087527009 2.391225661321518 2.229108802234927 1.9660589928571763 1.868573588166404 1.1446570175592055 1.088943661457756 1.6833666882079543 1.324757640452672 1.7175324613348206 1.0 12.788946845003926 -5.846223293270786 1.7712152412349933 1.3530180425240868 2.280529412548102 0.7306119738293164 0.23986791202519855 0.190171098583743 1.217281964570456 0.07750783835225594 0.14773936614269453 1.4248748033524458e-06 5.846223293270786 0.9275113700240152 DWEDDSDEDMSNFDR ddPTM_PC-9_Lapatinib_30min_R1 2 DWEDDSDEDMSNFDR 15 0 A0A087WYT3;Q15185-4;Q15185;B4DDC6;Q15185-2 A0A087WYT3 PTGES3 Prostaglandin E synthase 3 0 ; 148.13 0.00058262 9726600.0 13965.0 20596.9 15319.7 17211.0 23117.0 23049.2 20727.0 19132.0 20448.1 22880.0 False True 13765.856539132648 20549.209143519758 14060.173401752138 18476.75435421292 21757.303509770656 22063.439446309472 21800.142642010094 20020.94256479985 18145.019649961072 26834.777514316378 0.5129856780734833 0.7657678224668245 0.5239534180691836 0.6885376390527388 0.8107875497817381 0.8221957284549353 0.8123839532628768 0.7460819287254631 0.6761755203776401 1.0 14.711816306403746 -6.0884869529451855 3.9286209209515515 0.7984840443688532 0.6155057153919737 0.4672661387571496 0.10062688102686276 0.22598882651855634 6.384886877504698 0.028980884839498948 0.039124677284070035 8.156672910038865e-07 6.0884869529451855 -0.1829783289768795 DWEQFHQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DWEQFHQPR 9 0 Q9H773 Q9H773 DCTPP1 dCTP pyrophosphatase 1 0 ; 99.01299999999999 0.0026988000000000003 10297000.0 143070.0 144702.0 158200.0 162822.0 164371.0 123888.0 151704.0 117584.0 123197.0 109153.0 False True 167288.92523869494 159067.05825779753 161972.08797684126 153699.61121604653 132163.68249709607 117391.09518764055 137333.49887815228 114497.54459054608 124998.52305917448 128941.57484532715 1.2974009774532973 1.2336366951358213 1.2561665092979988 1.192009725338147 1.024988896371353 0.9104208268625378 1.06508315136442 0.8879800384623228 0.9694198570873468 1.0 16.976357983694506 -6.236335036871061 2.308522403898236 0.9644393693880259 1.2591188970479632 0.8867215261962496 0.047813606293710516 0.09084249712139328 0.9517730810176405 0.015269878331168517 0.019872039908675546 5.803165590584959e-07 6.236335036871061 0.2946795276599373 DWHRPCLK ddPTM_PC-9_AZD4547_30min_R2 1 DWHRPCLK 8 1 P50238 P50238 CRIP1 Cysteine-rich protein 1 0 60.681999999999995 0.03102 9766100.0 10843.0 14532.0 17618.0 19881.0 17526.0 17084.0 16288.0 20121.0 16775.0 16641.0 False True 14290.848451589258 19229.184811251424 17384.37380860329 15297.742608388086 15092.81742078089 16015.734779310418 17737.600445962995 17011.761784582428 17661.69225315875 16058.403655126187 0.889929581949904 1.1974530734325548 1.0825717289186354 0.9526315900961125 0.9398703473220352 0.9973428943043072 1.1045681019670204 1.0593681756873703 1.0998410945736041 1.0 13.971040863108273 -7.251438396621763 24.382308431651527 1.0708916918204259 1.0159965630815428 0.09266674430356847 0.08398837764382587 1396.4780081771962 3404605.4786241422 0.033731693005422635 0.025812689986535377 5.604819144153926e-08 7.251438396621763 -0.054895128738883026 DWHRPCLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DWHRPCLK 8 1 P50238 P50238 CRIP1 Cysteine-rich protein 1 0 52.403 0.046307 11009000.0 34336.0 39078.0 45421.0 49736.0 40714.0 41291.0 47619.0 36431.0 32887.0 36734.0 False True 40148.406633087485 42957.40558249514 46504.00890010174 46949.453166287574 32736.383967894457 39125.62727134883 43108.183588295244 35474.7248518352 33367.91015890861 43393.58341381598 0.9252152847166047 0.9899483334399629 1.0716793876325836 1.0819445980886533 0.7544060986093073 0.9016454552331743 0.993422994759408 0.8175108405668219 0.7689595450253754 1.0 15.405194107439012 -6.248205391326025 24.984965440227107 0.8710207007195101 1.019142180874213 0.39793396548331894 0.08707092946010783 835.3984450147931 1577180.844237464 0.02652813347330701 0.03404100378010029 5.646698617687386e-07 6.248205391326025 0.14812148015470283 DWHRPCLK ddPTM_PC-9_Lapatinib_30min_R1 2 DWHRPCLK 8 1 P50238 P50238 CRIP1 Cysteine-rich protein 1 0 ; 56.547 0.038338 13130600.0 72967.0 70778.0 74601.0 66116.0 66412.0 70224.0 66769.0 73184.0 70649.0 63849.0 False True 71926.477199491 70614.11788958737 68467.59374818762 70978.39119651058 62505.7767310156 67220.68322013934 70225.97211677392 76584.39581132703 62691.76565304852 74885.21457655531 0.9604896988838886 0.9429647533078565 0.9143005616708629 0.9478291755971296 0.8346878230163287 0.8976496041340644 0.9377815435780285 1.0226904769436782 0.8371714764729504 1.0 16.1923932789713 -7.517255079360766 24.935101051016904 0.9540057781673702 0.9153740932926185 0.0824897398469292 0.05582014805867087 644.899362080962 2859496.537538131 0.02506231272986666 0.015057230738237976 3.0390995107905604e-08 7.517255079360766 -0.03863168487475166 DWILPSDYDHAEAEAR ddPTM_PC-9_AZD4547_30min_R2 2 DWILPSDYDHAEAEAR 16 0 O43852;O43852-3;O43852-5;O43852-2;O43852-4;O43852-9;H0Y875;O43852-15 O43852 CALU Calumenin 0 ; 119.0 9.753700000000001e-05 4481900.0 31319.0 39347.0 52354.0 51281.0 46316.0 54789.0 53558.0 67893.0 54677.0 47561.0 False True 41277.79052433129 52065.14827747797 51659.75175250407 39458.95773355208 39885.822872354656 51363.03516879178 58324.55824440608 57401.69687593332 57567.114594692146 45895.903866441724 0.8993785293879545 1.1344181918497327 1.1255852352932256 0.8597490061069214 0.8690497301986565 1.1191202447664947 1.2708009502140336 1.2506932436274434 1.2542974371354347 1.0 15.486077780786163 -6.980094840268241 7.058629863032044 1.2124172519290157 0.9880167261222358 0.44303643246636193 0.11428300367119217 0.15248777246325562 32.535019101461096 0.04255833561593999 0.03679110939826642 1.0468999034013285e-07 6.980094840268241 -0.22440052580677994 DWILPSDYDHAEAEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DWILPSDYDHAEAEAR 16 0 O43852;O43852-3;O43852-5;O43852-2;O43852-4;O43852-9;H0Y875;O43852-15 O43852 CALU Calumenin 0 ; 192.46 4.506600000000001e-09 3995300.0 24868.6 40461.0 38593.0 28937.1 37756.0 26821.9 34433.0 20685.0 23165.9 25075.6 False True 29078.362802760934 44477.700682566545 39513.20348476757 27315.848102343993 30357.98283371381 25415.312346743623 31171.25696666812 20142.04066756913 23504.657461922983 29621.6077816596 0.981660516778734 1.5015289180253473 1.3339317627867724 0.9221595365008096 1.0248593883722321 0.8579990841172257 1.0523148235717303 0.6799779679764782 0.7934970186350261 1.0 14.854362327930323 -5.773377476170463 11.407377098343758 0.9002140398607114 1.2953457905641266 0.5274917525685971 0.1591169317757557 0.26406261129423747 247.28254232410188 0.04443383789146544 0.06816241081196381 1.685087759279588e-06 5.773377476170463 0.3951317507034152 DWILPSDYDHAEAEAR ddPTM_PC-9_Lapatinib_30min_R1 2 DWILPSDYDHAEAEAR 16 0 O43852;O43852-3;O43852-5;O43852-2;O43852-4;O43852-9;H0Y875;O43852-15 O43852 CALU Calumenin 0 ; 173.71 1.1679000000000001e-05 6315400.0 18722.9 30481.0 32046.0 28849.0 30674.0 30998.0 33106.0 36000.0 31192.0 32693.0 False True 18455.908012640662 30410.423117247065 29411.30158113728 30970.6516974428 28869.81562740432 29672.287799867307 34820.06669109792 37672.69142446133 27678.82849367843 38343.94148931576 0.48132527058500907 0.7930959086644938 0.7670390794157796 0.8077065240169046 0.7529172668764026 0.7738455319762904 0.9080982637322316 0.9824939732645516 0.7218566328500924 1.0 15.226711023149674 -3.696690966252697 0.3706995103601787 0.8985493988241463 1.145517954483088e-80 0.5441618309282161 0.09469797966634612 11.74082204914608 0.6852488540339234 0.07928589783702836 5.518831309705414 0.00020105229446038553 3.696690966252697 -0.8985493988241463 DWQSYYYHHPQDR ddPTM_PC-9_AZD4547_30min_R2 2 DWQSYYYHHPQDR 13 0 Q1KMD3 Q1KMD3 HNRNPUL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 0 ; 127.02 5.142e-05 36670000.0 43211.0 34247.0 79377.0 107288.0 74354.0 74106.0 59607.0 84972.0 57168.0 67682.0 False True 56951.19915536509 45316.67301341365 78324.40911598962 82554.40918307625 64031.23054346353 69472.14010510282 64911.907525940296 71841.5298623098 60189.78376921484 65312.473780797416 0.8719804328114328 0.6938440758729499 1.199225884152896 1.2639914614189387 0.9803828707876843 1.063688696561489 0.993866925693222 1.0999664490343037 0.9215664372356279 1.0 15.995070932471348 -5.256595617463465 24.990742018766493 1.0703558071760024 0.7829122424434233 0.5323715517020577 0.10579400518963783 301.53769927003947 1555730.2798946504 0.02788376685318614 0.06895000565535439 5.538655873972421e-06 5.256595617463465 -0.28744356473257915 DWQSYYYHHPQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DWQSYYYHHPQDR 13 0 Q1KMD3 Q1KMD3 HNRNPUL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 0 ; 113.07 0.00016222 28504000.0 42666.0 54437.0 79555.0 67841.0 73790.0 62623.0 58420.0 62322.0 60614.0 49578.0 False True 49888.51110808801 59841.14559840035 81451.8929140175 64040.08871348951 59331.37920594711 59338.939638509015 52886.034675827024 60686.11353561729 61500.365079578165 58566.09894076793 0.8518325790922803 1.021771070306765 1.3907686253167657 1.0934668668687975 1.0130669496350297 1.01319604193755 0.9030144679657499 1.0361986649818264 1.0501017857067425 1.0 15.837778179985532 -6.268769998881904 5.058015995222108 0.9992519886190837 1.106743160734731 0.09294465069193047 0.12901037889481598 0.4195756809412522 34.074228977162015 0.04240916974119076 0.05119167427925228 5.385549241552675e-07 6.268769998881904 0.10749117211564718 DWQSYYYHHPQDR ddPTM_PC-9_Lapatinib_30min_R1 2 DWQSYYYHHPQDR 13 0 Q1KMD3 Q1KMD3 HNRNPUL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 0 ; 159.66 0.00010749 36220000.0 132814.0 100432.0 150095.0 94077.0 134779.0 117557.0 97955.0 115969.0 169309.0 90335.0 False True 130920.04800489539 100199.45587452357 137754.76848345532 100995.736411672 126851.5642057091 112529.36114875156 103026.63060250395 121357.34310564902 150239.63751719025 105949.28438617861 1.2356860054637073 0.9457303695351328 1.3001953649950828 0.9532460459435362 1.1972857102398442 1.062105910395666 0.9724145962796524 1.1454286247305738 1.4180335279054461 1.0 16.693014317776928 -8.008659677885495 24.937431026720347 1.233254872513132 1.0920142333413665 0.08140213140735386 0.14814458889257034 726.616102415668 2092437.0508622108 0.07994994472435447 0.035332729599915416 9.802578347778766e-09 8.008659677885495 -0.14124063917176555 DWQSYYYHHPQDRDR ddPTM_PC-9_AZD4547_30min_R2 1 DWQSYYYHHPQDRDR 15 1 Q1KMD3 Q1KMD3 HNRNPUL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 0 50.897 0.026902999999999996 4371600.0 3705.3 3923.7 21457.0 56622.0 36583.0 18359.0 12677.0 11699.0 6762.3 18771.0 False True 4883.50832497221 5191.959292864521 21172.46616024525 43568.672701179516 31504.081918545402 17211.008827754606 13805.228441396906 9891.188366275526 7119.741372490931 18113.833003447744 0.2696010460095715 0.28662952186189944 1.1688562081926743 2.4052707504196795 1.7392277996903798 0.9501583030206088 0.7621373366293733 0.5460571688163881 0.3930554825770877 1.0 14.14480424168226 -7.192768683349897 3.1907302798628034 0.6257376177435512 1.199764474687856 0.12514660329021432 0.6063618025169851 0.5812624922439426 11.642734376438785 0.2961053262242878 0.21482809585468723 6.415511926191728e-08 7.192768683349897 0.5740268569443048 DWRQS(ph)PGEVGDR ddPTM_PC-9_AZD4547_30min_R2 1 DWRQSPGEVGDR 12 1 A0A0G2JHC2;Q6NYC8;Q6NYC8-2 A0A0G2JHC2 PPP1R18 Phostensin 1 DWRQS(1)PGEVGDR 65.565 0.0195 3920800.0 9547.8 8403.5 7797.0 13514.0 10376.0 13716.0 10066.0 10137.0 6629.4 12649.0 True False 12583.801793422843 11119.767035600831 7693.606685530699 10398.55608921868 8935.471502797127 12858.336351733875 10961.854499574138 8570.559575086332 6979.816549811665 12206.162360055952 1.0309384245618998 0.910996159774976 0.6303051244597268 0.8519103533513063 0.7320459321463726 1.053429896509662 0.8980590439666976 0.702150219067465 0.5718272741195678 1.0 13.575322065183968 -7.763211386562415 24.99471952432503 0.7277415344531869 0.8654516308672231 0.09308893314080702 0.15434456332117552 97.50636194317022 1375275.1164277592 0.07963813630302274 0.04138223461395519 1.724998069741242e-08 7.763211386562415 0.1377100964140362 DWSHYFK ddPTM_PC-9_AZD4547_30min_R2 2 DWSHYFK 7 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ; 104.45 0.0086853 21109100.0 345830.0 379060.0 455110.0 633440.0 566180.0 472880.0 430960.0 528380.0 412480.0 446410.0 False True 455796.746289138 501583.7320776875 449074.9440364083 487410.1945504419 487575.67997818737 443310.738845722 469314.60511985683 446731.0119644975 434282.85070538975 430781.32177662983 1.0580698912602327 1.1643581249276411 1.0424661454315889 1.1314561934585814 1.131840345276174 1.029085330388556 1.0894497541915418 1.037025027273903 1.008128321149856 1.0 18.716596171940992 -7.74631936349279 0.8335707157712305 0.9969027143657967 1.1042790762170782 0.4685715797703489 0.039437119435418284 0.5218061520897611 0.6731751080358122 0.03416835287488289 0.015181764133557787 1.793414333747477e-08 7.74631936349279 0.10737636185128152 DWSHYFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DWSHYFK 7 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ; 104.45 0.0086853 19772000.0 331440.0 380730.0 400980.0 465320.0 496560.0 407920.0 413360.0 453200.0 361170.0 305610.0 False True 387546.24576160545 418526.3582430884 410540.883925119 439249.62898779433 399262.63258578524 386527.9570978808 374203.54833276034 441303.98020509153 366451.4279834891 361014.6737925718 1.0734916719320884 1.159305669895183 1.1371861415278746 1.2167085187240172 1.1059457179161354 1.0706710423631371 1.036532793533391 1.2223990110126426 1.0150596487777146 1.0 18.461697952484258 -6.512394914334722 23.39282193661827 1.0816408717964998 1.1487013818937475 0.2243893705951635 0.06602480114714404 369.21404709710487 823840.2055470851 0.02056170124972079 0.02187709436986605 3.073300917891472e-07 6.512394914334722 0.06706051009724767 DWSHYFK ddPTM_PC-9_Lapatinib_30min_R1 1 DWSHYFK 7 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 0 104.45 0.0086853 8358300.0 168090.0 159350.0 184400.0 161590.0 171600.0 163720.0 155820.0 160710.0 176580.0 144940.0 False True 165693.0057760695 158981.03486543504 169239.34380458444 173473.86764843823 161506.82537858034 156718.0772499603 163887.59716688466 168177.17330069965 156691.70093016617 169992.68587958984 0.9747066758709495 0.9352227952798238 0.9955683853625383 1.0204784208852031 0.9500810257976613 0.9219107071522343 0.9640861682894429 0.989320054745319 0.9217555456542107 1.0 17.375113148610097 DWT(ph)EEDRAR ddPTM_PC-9_AZD4547_30min_R2 1 DWTEEDRAR 9 1 H0Y6J8;B0QY91;Q8N3F8 H0Y6J8;Q8N3F8 MICALL1 MICAL-like protein 1 1 DWT(1)EEDRAR 83.86200000000001 0.009875700000000001 2640400.0 0.0 0.0 782.06 0.0 988.26 1346.0 0.0 0.0 1389.4 1427.3 True False 0.0 0.0 771.6893734110738 0.0 851.0571576093183 1261.834407220312 0.0 0.0 1462.840847483683 1377.3306614363084 0.0 0.0 0.5602789475450582 0.0 0.6179032976161429 0.9161448608894289 0.0 0.0 1.0620839922043142 1.0 10.427659239448603 -9.750372424758373 0.17023394396853345 1.4929324813946787 2.765382645608229e-13 0.32423940230952386 0.36165243279444836 20.53667415395326 1.0876422987565664 7.2481705125667 2.0340886420441544 1.7767551185163052e-10 9.750372424758373 -1.4929324813944023 DWVLNEFK ddPTM_PC-9_AZD4547_30min_R2 1 DWVLNEFK 8 0 P17844-2;P17844;J3KTA4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 96.331 0.024887 0.0 25903.0 17200.0 19427.0 32828.0 29149.0 30871.0 23083.0 32337.0 26995.0 24589.0 False True 34139.61518412956 22759.563635667804 19169.38528662369 25260.011787544096 25102.16449836483 28940.63148982041 25137.34228230377 27340.059680336068 28421.900588615237 23728.14659430911 1.4387813666119842 0.9591799993821006 0.8078753732590821 1.0645589906125406 1.0579066678720395 1.2196751808993564 1.059389201865966 1.1522206157851886 1.1978137641577056 1.0 14.53431179556275 -6.552369975160875 24.42466644043259 1.1320271716841945 1.0437942252716448 0.02552623424432443 0.1594956307984051 509.26154563765743 421766.8315612484 0.05334078520702437 0.053341693403111595 2.803044708734842e-07 6.552369975160875 -0.08823294641254975 DWVLNEFK ddPTM_PC-9_Lapatinib_30min_R1 1 DWVLNEFK 8 0 P17844-2;P17844;J3KTA4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 108.98 0.017440999999999998 4390300.0 42806.0 38726.0 40001.0 42687.0 42349.0 38606.0 36884.0 37914.0 39340.0 36366.0 False True 42195.578590341 38636.33232631837 36712.27218832531 45826.34437965761 39858.11508133747 36954.911374981515 38793.67304520194 39675.62285186186 34909.11493143464 42651.814645350896 0.9893032439814462 0.9058543615923217 0.8607434992763431 1.0744289489369414 0.9344998662485292 0.866432335464762 0.9095433187959449 0.9302212152463847 0.8184672849608705 1.0 15.380319502667604 -6.532691463896128 23.83266926881725 0.9008160450513258 0.9541572952445158 0.11757262005379687 0.0674549205809311 262.1351908978703 636653.7808850608 0.022046486312637864 0.02207823264087931 2.932976181398262e-07 6.532691463896128 0.053341250193189915 DWVLNEFR ddPTM_PC-9_AZD4547_30min_R2 1 DWVLNEFR 8 0 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2;A0A0U1RQJ0 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 90.601 0.043093 3631100.0 16966.0 15819.0 19437.0 18933.0 21615.0 21654.0 18245.0 21108.0 17020.0 21258.0 False True 22360.83508527744 20932.1823925947 19179.252680089816 14568.289361934087 18614.130352058586 20299.971956871217 19868.76965475165 17846.24361358609 17919.642452981338 20513.76389043161 1.0900405798132136 1.020396963931044 0.9349455703268447 0.7101714458519863 0.9073971237789723 0.9895781225375166 0.9685579770185027 0.86996436679815 0.8735423956663424 1.0 14.324304603101234 -5.176832174768782 2.9802127010115678 0.8993938759571978 1.0754577816567201 0.37760566034973586 0.07847880005957332 0.2896618966946564 4.870112216437225 0.02212471988640139 0.07629892107590085 6.655302886341839e-06 5.176832174768782 0.17606390569952235 DWVLNEFR ddPTM_PC-9_Lapatinib_30min_R1 1 DWVLNEFR 8 0 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2;A0A0U1RQJ0 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 124.08 0.015285 4939500.0 21464.0 17212.0 22439.0 17649.0 19870.0 16923.0 17635.0 19464.0 20764.0 14443.0 False True 21157.91942398448 17172.14667150213 20594.152037044852 18946.96633533809 18701.285665923057 16199.242739439784 18548.054011282296 20368.368496825427 18425.339665386615 16939.45330591221 1.2490320107674278 1.0137367695041672 1.215750689537134 1.1185110872925996 1.1040076281207925 0.956302570507746 1.0949617839678836 1.2024218331601324 1.0877174919780792 1.0 14.048099694268178 -4.740491005894097 24.910854192525285 1.0960057926096836 1.2490325987330113 0.2689519067725996 0.07861667816050508 2325.2822451883053 2764971.9614131986 0.019750855415576418 0.8862184629003927 1.817644698571545e-05 4.740491005894097 0.15302680612332775 DY(ph)S(ph)GT(ph)Y(ph)T(ph)VK ddPTM_PC-9_AZD4547_30min_R2 1 DYSGTYTVK 9 0 Q5SZK8 Q5SZK8 FREM2 FRAS1-related extracellular matrix protein 2 5 DY(1)S(1)GT(1)Y(1)T(1)VK 41.427 0.043617 0.0 6991.9 8388.0 9744.1 12502.0 12162.0 11217.0 7440.6 11462.0 10917.0 10929.0 True False 9215.178759445444 11099.256963719848 9614.886867318166 9619.857053974536 10473.516231401187 10515.599216783248 8102.79898564785 9690.811270557318 11494.050332502784 10546.379036528702 0.8737765566292962 1.052423483479608 0.9116765890943046 0.9121478585830225 0.9930912017408869 0.9970814798483115 0.7683015144423306 0.9188756858626057 1.0898575039538883 1.0 13.364460132725704 -8.250919804781603 24.712189629759635 1.0449287526513429 0.9305615040980382 0.2734496145050944 0.07589960252376202 731.3907979957099 1718166.4374818339 0.05340197654672215 0.019681872146971754 5.6115158664981525e-09 8.250919804781603 -0.11436724855330471 DY(ph)STVSASPTALSTLK ddPTM_PC-9_AZD4547_30min_R2 1 DYSTVSASPTALSTLK 16 0 A0A2R8YF49;A0A2R8YFR7;Q12774 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 DY(0.957)S(0.043)TVSASPTALSTLK 209.25 4.3899e-17 3377700.0 7520.5 10851.0 13013.0 12464.0 12012.0 14847.0 11840.0 14844.0 16411.0 11782.0 True False 9911.862563882414 14358.373547129724 12840.439117456843 9590.61736688039 10344.341142212705 13918.614742942033 12893.737062880766 12550.200881185907 17278.451956279485 11369.5157661617 0.8717928509657731 1.2628834721231976 1.1293743182689406 0.8435378923897777 0.909831285251378 1.2242047092600934 1.1340621120607002 1.1038465612175146 1.519717489438217 1.0 13.47288318992439 -6.777953010698883 24.990909844846115 1.1989626254528498 1.0160030570375114 0.23997331415331824 0.17087492519162778 399.1564896466162 604059.7484990499 0.06109712497362401 0.05403679860212782 1.6674276132306629e-07 6.777953010698883 -0.18295956841533845 DY(ph)VFDKR ddPTM_PC-9_AZD4547_30min_R2 1 DYVFDKR 7 1 A0A0B4J291;Q8N8U2 A0A0B4J291 CDYL2 Chromodomain Y-like protein 2 1 DY(1)VFDKR 73.215 0.033943 63054000.0 58762.0 52906.0 75125.0 87528.0 80650.0 58194.0 85175.0 67956.0 51178.0 67652.0 True False 77447.0936744709 70006.82986678145 74128.79341419703 67349.77189411956 69453.13962033429 54555.1199805192 92755.40999416115 57454.96167352936 53883.16459804223 65283.52407166615 1.1863191329783602 1.0723506560388838 1.1354900714737892 1.0316503720017496 1.063869339285221 0.8356644460649879 1.4208088689013976 0.8800836427037418 0.8253715675472885 1.0 15.994431317120652 -2.0319143823444468 0.19142223435638472 0.9431340804394374 1.7838975838620914 0.12920111215580798 0.1594470199019501 104.58819096367372 1.4561173285104656 0.32928371242188503 25.00556070193168 0.009291495430664808 2.0319143823444468 0.840763503422654 DY(ph)VFDKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DYVFDKR 7 1 A0A0B4J291;Q8N8U2 A0A0B4J291 CDYL2 Chromodomain Y-like protein 2 1 DY(1)VFDKR 70.268 0.040917 35378000.0 30227.0 40408.0 35844.0 53634.0 50083.0 51064.0 40949.0 34039.0 37458.0 28151.0 True False 35343.834089536795 44419.43919283135 36698.656899127 50629.06086377407 40269.59567382373 48386.11394696557 37070.01427491339 33145.51231730172 38005.7523864262 33254.55345680662 1.06282690385375 1.3357400588922799 1.1035678752022284 1.5224700259329809 1.2109498245444414 1.4550222125163368 1.1147349887907099 0.9967210162768677 1.1428736349080968 1.0 15.02126427805135 -7.497472397922651 17.238655423954658 1.0530225726561955 1.2839272694172474 0.38270431733117083 0.13771555965760734 15.351393990761617 10417.126774586444 0.05545132375732506 0.03693262942801961 3.1807358371717646e-08 7.497472397922651 0.23090469676105196 DY(ph)VFDKR ddPTM_PC-9_Lapatinib_30min_R1 1 DYVFDKR 7 1 A0A0B4J291;Q8N8U2 A0A0B4J291 CDYL2 Chromodomain Y-like protein 2 1 DY(1)VFDKR 73.039 0.03436 65275000.0 90962.0 50062.0 76462.0 61282.0 56796.0 64371.0 55148.0 50760.0 79731.0 60125.0 True False 89664.86519961234 49946.08451480009 70175.58951185527 65788.88271075927 53455.370945232266 61618.00238612999 58003.2935987636 53118.49490849046 70750.85517534868 70517.5261384733 1.2715259611283007 0.7082790229583827 0.9951510405236483 0.9329437136176824 0.7580437640461669 0.8737969943122003 0.8225372722926234 0.7532665681462386 1.0033088091663511 1.0 16.10569424317012 -4.747319963300431 24.9906754125071 0.8649287863693779 1.271526996367432 0.5672861390150377 0.10453941071405118 515.7677458571741 912831.6066120105 0.024732480911464964 0.5106620182977682 1.789287124039437e-05 4.747319963300431 0.4065982099980542 DYAAYNVLDDPELR ddPTM_PC-9_Lapatinib_30min_R1 2 DYAAYNVLDDPELR 14 0 Q86SX6 Q86SX6 GLRX5 Glutaredoxin-related protein 5, mitochondrial 0 ; 158.86 1.8869e-12 0.0 8656.7 10592.1 11833.4 8599.2 9802.7 9490.3 7510.3 9072.6 10154.7 7712.0 False True 8533.253870555647 10567.574643226679 10860.503530244961 9231.613854090274 9226.124458849714 9084.421991969826 7899.146585819873 9494.146117154665 9010.970752268413 9045.00892440593 0.9434212770681267 1.1683321411339291 1.2007178346657377 1.0206307070831995 1.0200238093690634 1.004357438217396 0.8733155104475127 1.049655804267571 0.9962368006021892 1.0 13.142906210967954 -5.951775467822227 9.870585967491492 0.9908250498004723 1.1108430402843308 0.30775193443878346 0.07604770970914872 0.47013134442407606 92.28641020559742 0.021673463298041866 0.03215840419093024 1.1174408203355343e-06 5.951775467822227 0.12001799048385853 DYAFIHFDER ddPTM_PC-9_AZD4547_30min_R2 3 DYAFIHFDER 10 0 O60506-2;O60506;O60506-4;O60506-3;B7Z645;O60506-5 O60506-2 SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0 ;; 112.13 0.0012558 9509100.0 53345.0 63641.0 77588.0 82907.0 76179.0 78818.0 68025.0 86945.0 71686.0 72502.0 False True 70307.60035507058 84211.70868241465 76559.13242490133 63794.072050381226 65602.8607952565 73889.49800021591 74079.09321811343 73509.64804733956 75475.17561013043 69963.72704789133 1.0049150227080366 1.2036481221872348 1.0942689255604598 0.9118163760302982 0.9376696120026634 1.056111518324879 1.0588214256711204 1.050682277075105 1.0787757999008034 1.0 16.09431952487374 -5.545809177451899 24.98510394067752 1.0150384831267645 1.115450854639645 0.2575638966864062 0.0676762111866992 280.53348647132935 305669.3007627003 0.019136065312563056 0.03314669933860028 2.845711196046625e-06 5.545809177451899 0.10041237151288063 DYAFIHFDER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DYAFIHFDER 10 0 O60506-2;O60506;O60506-4;O60506-3;B7Z645;O60506-5 O60506-2 SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0 ;; 128.01 0.00024649 8349800.0 70370.0 96388.0 95561.0 83218.0 85952.0 70581.0 79221.0 69736.0 67070.0 55873.0 False True 82282.25112914637 105956.76363390013 97839.53665711079 78555.56525639616 69110.32261159479 66879.60810925068 71716.6133696283 67905.50389139952 68050.77186602597 66002.33260957524 1.2466567146326786 1.6053487724542712 1.4823648314956188 1.1901937727122052 1.0470890933568104 1.0132915832666824 1.0865769516640398 1.0288349094127043 1.0310358615439836 1.0 16.01022939166902 -5.928506184694518 3.0131151690641564 1.0395347410571272 1.4621381803790483 0.8190847782087087 0.0859198345271886 0.09641481514476635 1.772894963425319 0.025047825986401102 0.03901048648522341 1.1789457340110414e-06 5.928506184694518 0.4226034393219211 DYAFIHFDER ddPTM_PC-9_Lapatinib_30min_R1 1 DYAFIHFDER 10 0 O60506-2;O60506;O60506-4;O60506-3;B7Z645;O60506-5 O60506-2 SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0 105.46 0.0020623 1580600.0 9798.2 14430.0 15146.0 14183.0 15241.0 17389.0 13331.0 12656.0 14830.0 13009.0 False True 9658.475871230185 14396.588221576549 13900.75434525074 15226.065133101025 14344.554344958886 16645.31300573883 14021.21395091604 13244.043962999516 13159.68923317681 15257.588316597095 0.6330276889646946 0.9435690571042635 0.911071530887329 0.9979339340633684 0.9401586965978747 1.0909530825151559 0.9189665928830878 0.8680299722461865 0.8625012656070812 1.0 13.89723932084051 -4.761237657734628 7.557621034619464 0.948019767976029 0.628047694216611 0.6823634395167693 0.06450297503097123 0.06176497541164499 25.741237661579916 0.01694876140635638 0.10094488604793266 1.7328554726746818e-05 4.761237657734628 -0.31997207375941805 DYAFVHFEDR ddPTM_PC-9_AZD4547_30min_R2 2 DYAFVHFEDR 10 0 O43390-4;O43390;O43390-2;B4DT28;O43390-3;A0A286YEZ8 O43390-4 HNRNPR Heterogeneous nuclear ribonucleoprotein R 0 ; 107.11 0.0018622 13781300.0 76628.0 75723.0 106568.0 140292.0 115037.0 106907.0 102247.0 121531.0 96122.0 102223.0 False True 100994.11003858555 100198.97890602758 105154.83868970587 107949.84688979338 99066.09823316045 100222.08838982329 111346.78492131495 102751.17645455454 101202.8126830478 98644.20388425949 1.0238220398340203 1.015761443253091 1.0660011896196697 1.0943354260981448 1.0042769299389953 1.0159957143291982 1.1287716919684359 1.0416342005771957 1.0259377510085677 1.0 16.589946663411638 -9.62920200728411 20.239453254219125 0.9999999999969954 1.0475407575196085 0.11972010557575097 0.037509894012199424 0.0 0.0 0.03739351500117467 0.009069259533115393 2.348540169216247e-10 9.62920200728411 0.04754075752261311 DYAFVHFEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DYAFVHFEDR 10 0 O43390-4;O43390;O43390-2;B4DT28;O43390-3;A0A286YEZ8 O43390-4 HNRNPR Heterogeneous nuclear ribonucleoprotein R 0 ; 117.14 0.00082429 10354700.0 97450.0 118665.0 120933.0 130950.0 135406.0 115958.0 117733.0 129761.0 107952.0 81029.0 False True 113946.36027476612 130445.27697033602 123816.5013609566 123613.29604562823 108874.1663201042 109876.95834760767 106580.4779268941 126354.91124314441 109530.59377488091 95718.91627478898 1.190426769434476 1.3627951720206999 1.2935426578118094 1.2914197199094934 1.1374362618936182 1.1479126866853977 1.1134735126014574 1.320062075090841 1.1442941274057208 1.0 16.546516442390775 -6.255723328844972 23.715021694340333 1.158549210780325 1.2907779304691416 0.3992816865150143 0.08323645399573017 252.00909342831676 1045544.3554887654 0.02432031172048332 0.030481180733270268 5.549791547615554e-07 6.255723328844972 0.13222871968881655 DYAFVHFEDR ddPTM_PC-9_Lapatinib_30min_R1 2 DYAFVHFEDR 10 0 O43390-4;O43390;O43390-2;B4DT28;O43390-3;A0A286YEZ8 O43390-4 HNRNPR Heterogeneous nuclear ribonucleoprotein R 0 ; 115.91 0.00090998 5949400.0 40510.0 54478.0 70933.0 61400.0 68138.0 66191.0 61023.0 58048.0 71298.0 54902.0 False True 39932.31997137585 54351.85953811832 65101.16254929828 65915.56082439561 64130.256804462246 63360.16522875718 64182.47235216781 60745.12199464255 63267.66843877546 64391.737547683406 0.6201466444635874 0.8440812689340716 1.0110173296859637 1.023664888303158 0.9959392190181616 0.9839797409075609 0.9967501234865633 0.9433682690991144 0.9825432710512657 1.0 15.974587959757002 -4.864971003530006 2.3018757451006437 0.9912336493418631 0.5650673522375109 0.9650617950367107 0.021898491683528278 0.08776001700612242 0.650022375689065 0.0065486877560382035 0.07156496909867001 1.364674248533862e-05 4.864971003530006 -0.42616629710435217 DYAS(ph)HLSPGSIIQPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DYASHLSPGSIIQPQR 16 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;C9JE98;C9JQE8;C9J330 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 DY(0.303)AS(0.393)HLS(0.303)PGS(0.001)IIQPQR 101.53 0.00092137 4654200.0 8336.4 7878.0 14148.0 11111.0 17231.0 14213.0 10497.0 10677.0 8828.2 10409.0 True False 9747.587868594788 8660.075776111791 14485.341976588787 10488.486692348022 13854.709243768477 13467.645259443476 9502.648168301204 10396.74006321661 8957.295723686466 12296.069302401338 0.7927401536921357 0.7042962725023466 1.1780465464487826 0.8529950860231158 1.1267592027203968 1.0952805265023464 0.7728199910556296 0.8455336260333371 0.7284682204854821 1.0 13.58590958094882 -10.353930964083405 4.0962171883578815 1.0000014220504854 0.9078397110188412 0.03059329137233935 0.16372043705307435 101589031.89273395 253389313.3531207 2460.4050596297816 0.04249195869495897 4.42658732277039e-11 10.353930964083405 -0.09216171103164417 DYASHLS(ph)PGSIIQPQR ddPTM_PC-9_AZD4547_30min_R2 4 DYASHLSPGSIIQPQR 16 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;C9JE98;C9JQE8;C9J330 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 DY(0.014)AS(0.004)HLS(0.982)PGS(0.001)IIQPQR;DY(0.003)AS(0.003)HLS(0.994)PGSIIQPQR;DY(0.006)AS(0.141)HLS(0.798)PGS(0.055)IIQPQR;DYASHLS(0.955)PGS(0.045)IIQPQR 99.238 0.0020962 13229500.0 68817.6 65891.2 77847.4 69031.8 77390.6 64898.0 70854.1 78006.5 67009.8 57178.9 True False 90700.16530499757 87189.24182735539 76815.09261141234 53117.58504067828 66646.25104899508 60839.91780073094 77159.97763742066 65952.3878360435 70551.80122478188 55177.08411490263 1.6438013490549894 1.5801712472842813 1.3921557081822227 0.962674738847461 1.2078610553288511 1.1026301729543342 1.398406220175392 1.195285849080064 1.2786431605893205 1.0 15.751781597673723 -5.457742863730599 3.5345441407871085 1.1799666043343973 1.6071960724825225 0.6803082956611317 0.12281876763011725 0.1381418368802256 3.3526781666400156 0.033437697648396936 0.07364400102469501 3.485436190138777e-06 5.457742863730599 0.42722946814812524 DYASHLS(ph)PGSIIQPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DYASHLSPGSIIQPQR 16 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;C9JE98;C9JQE8;C9J330 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 DYAS(0.001)HLS(0.999)PGSIIQPQR 105.01 0.00066868 5133100.0 7398.8 10157.0 11240.0 11042.0 13813.0 11026.0 12305.0 10390.0 8790.2 9621.4 True False 8651.270707038906 11165.319834725498 11508.004227937376 10423.352538647003 11106.441807450168 10447.77714983633 11139.381319514747 10117.273509114972 8918.740045575409 11365.683657039512 0.7611746876027654 0.9823711596803141 1.012521954260949 0.9170897988341544 0.9771908265783222 0.919238777454917 0.9800889815031407 0.8901596960116589 0.784707749634704 1.0 13.472396845839505 -9.852717579043077 6.303353811024678 0.9999999979532289 0.9221262381341199 0.08649340279476092 0.08002339048021313 14322261.566523163 3198142.242595311 0.07721676355667219 0.01930419095058465 1.4037262485894646e-10 9.852717579043077 -0.07787375981910905 DYASHLS(ph)PGSIIQPQR ddPTM_PC-9_Lapatinib_30min_R1 1 DYASHLSPGSIIQPQR 16 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;C9JE98;C9JQE8;C9J330 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 DYASHLS(1)PGSIIQPQR 113.81 0.00011548 4358500.0 34638.0 33885.0 35989.0 26868.0 41022.0 34273.0 29009.0 30544.0 36731.0 33450.0 True False 34144.055768168735 33806.54136438821 33030.12334155745 28843.962349020556 38609.16661235505 32807.22368426519 30510.94407787287 31963.185746354084 32593.96798542262 39231.78793067669 0.8703160770674516 0.8617129921308967 0.8419224583881393 0.7352191646220249 0.9841296726159454 0.8362408499514774 0.7777097524024723 0.8147267160709992 0.8308050615234965 1.0 15.25973546515418 -12.078783085737545 2.1072343522765036 3.3963086486071563 0.8385296962119184 0.3812480933990495 0.06145105947534601 2489590.6504168482 211062.5719387134 28384219.87772866 0.015471792138289819 8.340976819852952e-13 12.078783085737545 -2.557778952395238 DYDDMS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 7 DYDDMSPR 8 0 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR 138.08 0.0030556999999999997 2504777000.0 3750751.0 3715480.0 4745100.0 6182870.0 5448480.0 4897170.0 4119845.0 5343442.0 4349688.0 4544710.0 True False 4943411.797532683 4916436.249828544 4682176.873606737 4757504.845889267 4692052.5996106425 4590949.185740791 4486503.223802696 4517735.818981798 4579603.627615948 4385601.086202055 1.1271913930078155 1.1210404578967748 1.0676248891714675 1.0848010916581747 1.0698767414967911 1.0468232507933293 1.0230075959070009 1.0301292183631257 1.0442362489429926 1.0 22.06434315991948 -1.5228787452803376 0.19157655180797048 0.9976282138339319 1.6274323634327963 0.9015113444161182 0.01226446359054979 15.648809030239429 0.18390317694203992 0.025364755837211598 2.920484610839886 0.029999999999999995 1.5228787452803376 0.6298041495988644 DYDDMS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 DYDDMSPR 8 0 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR 107.55 0.0038082 1129967800.0 4237137.0 4256797.0 4720394.0 5326371.0 5374546.0 4740418.0 4911683.0 4741264.0 4819288.0 3929894.0 True False 4954400.606829575 4679383.673968683 4832946.095153939 5027951.701197762 4321442.292801272 4491822.135051041 4446412.828734502 4616810.843784454 4889760.969802845 4642352.673176223 1.0672176277033802 1.0079767745794985 1.0410553517570897 1.0830611233501393 0.9308733301911357 0.9675745147509028 0.9577929859629423 0.9944980850896247 1.0532937314427147 1.0 22.146424695736748 -6.2538593331278145 24.996446199779722 0.9815981760496111 1.046211767154081 0.4566398834891391 0.03502752556352085 579.469842316401 1910897.9618799358 0.010875221334692967 0.013777811643411218 5.573662492014794e-07 6.2538593331278145 0.06461359110446985 DYDDMS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 11 DYDDMSPR 8 0 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR 133.75 0.0037311999999999996 3088201300.0 7727148.0 6980256.0 7417314.0 6270448.0 6601524.0 6427773.0 6177685.0 6268428.0 7527197.0 5190516.0 True False 7616957.452534607 6964093.646097643 6807491.074580018 6731597.663521341 6213235.337415555 6152872.1326607065 6497535.301655153 6559682.048901478 6679404.808961621 6087689.774672174 1.2512065716989964 1.1439632937722528 1.1182388272974384 1.105772125828117 1.0206228581597099 1.0107072404148654 1.0673236551389562 1.0775322481432985 1.0971986182264537 1.0 22.537463411091792 -4.374048616471723 0.7455385631332123 1.050398716436471 1.4952699178012308 0.7846728575874282 0.03276690440736811 2.306448672145476 0.6391594649625373 0.013791916920744239 0.9870269115144836 4.22621301883135e-05 4.374048616471723 0.44487120136475977 DYDDMSPR ddPTM_PC-9_Lapatinib_30min_R1 3 DYDDMSPR 8 0 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 ;; 115.49 0.016732 32542000.0 285311.0 258699.0 254411.0 222692.0 241325.0 260681.0 216787.0 241811.0 262152.0 185583.0 False True 281242.41282037064 258099.99835991953 233494.30963485953 239069.51255873457 227130.73796320465 249532.28130709112 228011.1701130624 253046.42183445574 232625.6811770577 217660.77427619693 1.2921134446737421 1.1857901324581706 1.0727440918618203 1.0983582749520655 1.0435079022322642 1.1464274265166925 1.0475528761270119 1.1625724601776746 1.0687533477293953 1.0 17.731721910184568 -4.941369338713665 2.300588667583045 1.0860334550701145 1.3098820205467692 0.6816042722120608 0.04605395704043602 0.2310201176279134 1.9019023343871915 0.011427462696262897 0.09233911253795218 1.1445391726247192e-05 4.941369338713665 0.22384856547665466 DYDEEEQGYDS(ph)EK ddPTM_PC-9_Lapatinib_30min_R1 1 DYDEEEQGYDSEK 13 0 Q5T757;Q05519-2;Q05519 Q5T757 SRSF11 Serine/arginine-rich splicing factor 11 1 DYDEEEQGYDS(1)EK 151.07 6.0947e-05 7338700.0 47210.0 63959.0 46168.0 47459.0 48655.0 38226.0 51185.0 61753.0 47031.0 51039.0 True False 46536.776742746304 63810.90686512922 42372.24525363371 50949.29317858294 45793.20855941047 36591.163089158246 53835.10884987155 64622.269820409994 41733.873521614194 59861.02314480741 0.7774136541263427 1.0659842333594398 0.7078436523066554 0.8511263339975587 0.7649920792137808 0.6112685879197558 0.8993349264953454 1.0795383444095976 0.6971794220866798 1.0 15.869329317144652 -10.451681012627525 6.4955822198877575 1.0000000051366689 0.833650937060911 0.11081249347737676 0.14520388455086275 3.878528615448098e-08 6.321773622606795e-09 0.14131955081198622 0.03427502150014008 3.534426765567317e-11 10.451681012627525 -0.1663490680757579 DYDT(ph)LSK ddPTM_PC-9_Lapatinib_30min_R1 1 DYDTLSK 7 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 DYDT(0.987)LS(0.013)K 114.86 0.020734 6495300.0 59948.0 70345.0 58283.0 42622.0 62278.0 60410.0 78941.0 57818.0 44242.0 33857.0 True False 59093.1305268832 70182.12047448404 53491.19671888612 45756.56406282393 58614.930483258984 57826.405122588 83028.1787187204 60504.43535498625 39259.0000710862 39709.13733838327 1.4881494408533313 1.7674048135678149 1.3470752653994569 1.1522930773566604 1.4761068714177574 1.4562493420548925 2.090908649341634 1.5236905007377741 0.9886641388489202 1.0 15.277183398907045 -8.257314054982077 8.240226687456063 0.9926803988877373 1.540149828164128 0.45904170496515007 0.23596585988998015 0.10488262216930723 86.82803430517274 0.19704673489429572 0.06461333900999777 5.529501051938749e-09 8.257314054982077 0.5474694292763906 DYEEVGADSADGEDEGEEY ddPTM_PC-9_AZD4547_30min_R2 2 DYEEVGADSADGEDEGEEY 19 0 Q9BQE3;F5H5D3 Q9BQE3 TUBA1C Tubulin alpha-1C chain 0 ; 201.46 4.106699999999999e-59 6520300.0 148544.0 177506.0 178107.0 139733.0 175405.0 199699.0 211643.0 221656.0 187017.0 175495.0 False True 195777.90209285915 234881.3431809795 175745.18480695353 107519.71570332938 151053.04346069074 187211.78996098766 230478.81699318183 187404.15834816408 196902.33681722748 169350.9734665208 1.1560482829557677 1.3869500621879416 1.0377571572784423 0.6348928116706992 0.8919526139632884 1.105466275917202 1.3609535999434066 1.106602191366867 1.1626879538200785 1.0 17.36965675422008 -6.996425115282106 24.775900438887508 1.175982381956285 1.01899107197863 0.09387060288958804 0.1970724257265381 236.98288864752521 1642401.0706768127 0.07828656990442374 0.06870313602811125 1.0082654480098839e-07 6.996425115282106 -0.15699130997765498 DYEEVGADSADGEDEGEEY ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DYEEVGADSADGEDEGEEY 19 0 Q9BQE3;F5H5D3 Q9BQE3 TUBA1C Tubulin alpha-1C chain 0 ; 126.66 0.00014396 10368100.0 96432.0 126695.0 119526.0 115538.0 123784.0 101714.0 119427.0 81698.0 102059.0 92772.0 False True 112756.0329811826 139272.44230191497 122375.95314487904 109064.78043925019 99529.41379087922 96379.93878273641 108114.00998339584 79553.51406618646 103551.41979834145 109590.829217252 1.0288820130893974 1.2708403002026964 1.1166623523057928 0.9951998832223545 0.9081910822444175 0.8794525917097824 0.9865242443696769 0.725913971400656 0.9448912882396566 1.0 16.74176755014073 -5.901397629248512 2.239032135169034 0.8961977380090809 1.1590839994223856 0.5688612873081831 0.08980623853848511 0.19585055933742462 1.994800236824366 0.02668021883132912 0.044759500206907686 1.2548805001250304e-06 5.901397629248512 0.26288626141330473 DYEEVGADSADGEDEGEEY ddPTM_PC-9_Lapatinib_30min_R1 2 DYEEVGADSADGEDEGEEY 19 0 Q9BQE3;F5H5D3 Q9BQE3 TUBA1C Tubulin alpha-1C chain 0 ; 221.32 9.5929e-28 16248300.0 144515.0 160023.0 141691.0 127979.0 150439.0 152339.0 148367.0 151318.0 157020.0 121413.0 False True 142454.18959919442 159652.47657528368 130041.71292307667 137391.0025854289 141590.47379445375 145823.8160895537 156048.71729469363 158348.7866935181 139334.75410609733 142399.075277347 1.0003870412904021 1.121162312777191 0.9132202064500615 0.9648307218135792 0.994321581925175 1.0240503023319247 1.0958548501158563 1.1120071277506982 0.9784807509088007 1.0 17.11958025208159 -7.013591943962797 6.398581213303819 1.056628575961904 0.9997520058568324 0.11120249836590579 0.06115682645912944 0.31518427306438024 56.21757381224044 0.023381331843379732 0.019127943814110857 9.691880619391684e-08 7.013591943962797 -0.05687657010507163 DYEEVGVDSVEGEGEEEGEEY ddPTM_PC-9_AZD4547_30min_R2 2 DYEEVGVDSVEGEGEEEGEEY 21 0 P68363;P68363-2;Q71U36-2;Q71U36 P68363;Q71U36-2 TUBA1B;TUBA1A Tubulin alpha-1B chain;Tubulin alpha-1A chain 0 ; 144.57 6.8605e-05 19467600.0 192879.0 229072.0 245385.0 202234.0 231085.0 266552.0 237189.0 313550.0 252119.0 237626.0 False True 254210.5098675722 303115.044252889 242131.03456828903 155612.07578415365 199002.83656745148 249884.46130266666 258298.361504023 265098.0521622094 265445.49562885996 229306.7860677258 1.1086043907679692 1.321875594921835 1.0559261621536817 0.6786195840632191 0.8678453873086684 1.089738623037799 1.126431388854469 1.1560846353841123 1.1575998258963893 1.0 17.80691952486964 -9.607112308867237 15.820577337398582 1.000000642229239 1.0583734750849474 0.011975569315945012 0.1665789491631043 0.0 0.0 0.18172294126621308 0.044074287143441825 2.4710850380042417e-10 9.607112308867237 0.05837283285570849 DYEEVGVDSVEGEGEEEGEEY ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DYEEVGVDSVEGEGEEEGEEY 21 0 P68363;P68363-2;Q71U36-2;Q71U36 P68363;Q71U36-2 TUBA1B;TUBA1A Tubulin alpha-1B chain;Tubulin alpha-1A chain 0 ;; 140.63 2.815e-06 23615000.0 111280.9 140874.0 137218.0 122345.0 134416.7 115379.3 141227.9 97308.5 107030.4 95998.1 False True 130118.55847203963 154859.03971616793 140489.79752216273 115490.40629784165 108078.7125533549 109328.60639435083 127849.77091054809 94754.25498187807 108595.51711837671 113401.79560945842 1.1474118004282017 1.3655783745213617 1.238867486772361 1.0184177920389914 0.9530599755718546 0.9640817925922871 1.127405172232428 0.8355622102157875 0.9576172628903167 1.0 16.791083958600126 -5.7818567516198165 3.8171943225674014 0.9732255904404048 1.2678598316015268 0.6953059476794372 0.08268259290970133 0.11419093510519994 3.585283618580742 0.023341706466539443 0.038626162009610485 1.652506773799444e-06 5.7818567516198165 0.294634241161122 DYEEVGVDSVEGEGEEEGEEY ddPTM_PC-9_Lapatinib_30min_R1 2 DYEEVGVDSVEGEGEEEGEEY 21 0 P68363;P68363-2;Q71U36-2;Q71U36 P68363;Q71U36-2 TUBA1B;TUBA1A Tubulin alpha-1B chain;Tubulin alpha-1A chain 0 ; 196.67 2.6810000000000002e-18 22331600.0 187117.0 206241.0 189598.0 170238.0 211990.0 193774.0 192829.0 191903.0 200912.0 158208.0 False True 184448.67726694443 205763.46163590884 174009.98430944447 182757.87041731994 199521.16498837597 185486.73772925607 202812.74210045676 200819.5139563448 178283.17486284676 185554.04200109083 0.9940428959551315 1.1089139283460028 0.9377860079621521 0.9849306889054217 1.075272534279814 0.9996372794086892 1.0930117173047864 1.082269681601246 0.9608153664569521 1.0 17.501479902642366 -6.248750346543296 24.825406149668577 1.0403969224092076 1.0088371810409642 0.05440604197614163 0.05587347665026429 2224.0596405837496 4351255.412741324 0.016550589403704404 0.021228584001513597 5.639617551349514e-07 6.248750346543296 -0.031559741368243355 DYEIESQNPLAS(ph)PTNTLLGSAK ddPTM_PC-9_AZD4547_30min_R2 4 DYEIESQNPLASPTNTLLGSAK 22 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 DYEIESQNPLAS(0.968)PT(0.021)NT(0.011)LLGSAK;DYEIESQNPLAS(0.974)PT(0.025)NTLLGSAK;DYEIESQNPLAS(0.995)PT(0.004)NTLLGSAK;DYEIESQNPLAS(0.947)PT(0.049)NT(0.004)LLGSAK 158.91 6.3574e-07 127801000.0 152412.0 134958.0 176407.0 230158.0 218649.0 194947.0 172075.0 204110.0 167648.0 190056.0 True False 200875.84563346114 178580.53425246847 174067.72791771367 177098.6290056527 188293.36050646543 182756.93327219802 187389.34164655497 172569.48948119459 176509.5310198245 183402.1972885444 1.0952750218004512 0.9737098949338645 0.9491038302221377 0.9656298104598258 1.0266690546254786 0.9964816996421738 1.0217398941613423 0.9409346890740525 0.9624177552361831 1.0 17.484651397984265 -4.7590290083579845 24.991090060452457 0.9815818342138212 1.095275170930495 0.6037759222687792 0.027563510859847984 47.83048701328861 495804.9967642188 0.007353309751825153 0.048149613699779346 1.7416905346583076e-05 4.7590290083579845 0.11369333671667392 DYEIESQNPLAS(ph)PTNTLLGSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DYEIESQNPLASPTNTLLGSAK 22 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 DYEIESQNPLAS(0.896)PT(0.101)NT(0.002)LLGSAK;DYEIESQNPLAS(0.999)PT(0.001)NTLLGSAK;DYEIESQNPLAS(0.993)PT(0.005)NT(0.002)LLGSAK;DYEIESQNPLAS(0.763)PT(0.225)NT(0.012)LLGSAK 158.91 2.2334e-06 90022100.0 163881.0 162994.0 186022.0 200829.0 236679.0 229547.0 228836.0 243333.0 220669.0 181820.0 True False 191622.81650270868 179174.96713018126 190457.46997236361 189577.20222640267 190303.44896441707 217509.15122560135 207158.99745083094 236945.76658262557 223895.86666026732 214782.52671367212 0.8921713485481163 0.8342157524249656 0.8867456440079207 0.8826472298611571 0.8860285418753442 1.0126948153262212 0.9645058218678834 1.1031892128659953 1.0424305463113592 1.0 17.71251710440395 -6.876035114412302 1.325191781837721 1.045509868367993 0.8669602194528652 0.7956256532320705 0.0372873104116287 0.17357002647143555 0.6333363444249703 0.018165067209182966 0.014786646055436614 1.3303468498686463e-07 6.876035114412302 -0.17854964891512792 DYEIESQNPLAS(ph)PTNTLLGSAK ddPTM_PC-9_Lapatinib_30min_R1 4 DYEIESQNPLASPTNTLLGSAK 22 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 DYEIESQNPLAS(0.996)PT(0.004)NT(0.001)LLGSAK;DYEIESQNPLAS(0.848)PT(0.148)NT(0.004)LLGSAK;DYEIESQNPLAS(0.966)PT(0.03)NT(0.004)LLGSAK;DYEIESQNPLAS(0.963)PT(0.035)NT(0.003)LLGSAK 125.53 4.7956e-07 100537300.0 343603.0 292903.0 321738.0 295404.0 361710.0 350201.0 322475.0 337074.0 381165.0 294875.0 True False 338703.15821092704 292224.8010994065 295285.9435845954 317128.9955988563 340434.92894922144 335223.71958840353 339171.1776177069 352735.68858913507 338234.18385460856 345843.7508537612 0.9793531251462353 0.8449619239266599 0.853813153644219 0.9169718834473118 0.9843605041548752 0.9692924008626996 0.9807063935098373 1.0199278943695245 0.9779970955659386 1.0 18.399760862639546 -6.177371020486557 3.187753980634932 0.9891654097978815 0.8875319730498629 0.59947879970055 0.036262724665640476 0.17045041372979935 3.3571097822077025 0.011286607886088354 0.014877185964392987 6.647050518941477e-07 6.177371020486557 -0.10163343674801861 DYEIESQNPLASPTNT(ph)LLGSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DYEIESQNPLASPTNTLLGSAK 22 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 DYEIESQNPLAS(0.178)PT(0.12)NT(0.692)LLGS(0.01)AK 65.454 0.0062085000000000005 3141400.0 6643.9 7606.8 6186.6 9424.7 8241.7 9300.2 8573.4 8720.6 9295.2 6973.4 True False 7768.5810469935295 8361.95283241016 6334.112006811151 8896.66461428966 6626.798048538481 8812.481139933601 7761.265485959177 8491.693490239466 9431.124715209273 8237.622218595976 0.9430610971035293 1.0150930220535623 0.7689247987741225 1.0800039596627693 0.8044552023251141 1.069784569634659 0.9421730300326895 1.0308427923618466 1.1448843446497257 1.0 13.008012249681627 -7.554911588316894 1.239081546982491 1.070600370161168 0.9345090463312105 0.2066308800445803 0.10062666315613773 0.7144854438529976 2.0520058348245853 0.07246858033601056 0.03265584059754333 2.7866884121632466e-08 7.554911588316894 -0.13609132382995748 DYEPPS(ph)PSPAPGAPPPPPQR ddPTM_PC-9_AZD4547_30min_R2 2 DYEPPSPSPAPGAPPPPPQR 20 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-1;H0Y8L4 A8MQ02 MLLT4 Afadin 1 DYEPPS(0.981)PS(0.019)PAPGAPPPPPQR;DYEPPS(0.993)PS(0.007)PAPGAPPPPPQR 233.57 4.0754e-44 17531800.0 50090.0 44872.0 49632.0 80766.0 53388.0 56929.0 53357.0 87729.0 72453.0 56395.0 True False 66017.57806327633 59375.99648021428 48973.84725102727 62146.64652226112 45975.99774396038 53369.22063049418 58105.66963379463 74172.49886186713 76282.71766426892 54420.628215302066 1.2130984192628893 1.0910568001035839 0.8999133023101842 1.1419685615607547 0.8448266631922634 0.980679980748325 1.0677140551173645 1.362948229271106 1.4017243123779235 1.0 15.731865990269156 -7.664733466221958 5.689341421336569 1.2852454509921543 1.0229565018574742 0.3277917854847303 0.14324230891130132 0.20451090323665136 9.826617417646066 0.06827146579864739 0.03846056876040193 2.164046227586641e-08 7.664733466221958 -0.26228894913468004 DYEPPS(ph)PSPAPGAPPPPPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DYEPPSPSPAPGAPPPPPQR 20 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-1;H0Y8L4 A8MQ02 MLLT4 Afadin 1 DYEPPS(0.892)PS(0.108)PAPGAPPPPPQR 188.16 1.0094e-11 5242300.0 23551.0 19469.0 22295.0 20306.0 33922.0 26431.0 29724.0 39861.0 30356.0 25824.0 True False 27537.71914654715 21401.75365386145 22826.597354258352 19168.320652940252 27275.227611114522 25044.91183088373 26908.327536875775 38814.6909862206 30799.899072090157 30505.686777328498 0.902707726187397 0.7015660329197049 0.7482735111285165 0.6283523722267399 0.8941030506936556 0.8209915749052024 0.8820757825676542 1.2723755826099699 1.0096445065114978 1.0 14.896790590116579 -7.575666815210441 5.672359330854759 1.1052090340607057 0.7809061296604756 0.6401713106096781 0.1041617361495572 0.11653895163583101 8.131257120610922 0.04965245818132731 0.028403888281579998 2.6566429204901722e-08 7.575666815210441 -0.32430290440023013 DYEPPS(ph)PSPAPGAPPPPPQR ddPTM_PC-9_Lapatinib_30min_R1 2 DYEPPSPSPAPGAPPPPPQR 20 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-1;H0Y8L4 A8MQ02 MLLT4 Afadin 1 DYEPPS(0.63)PS(0.37)PAPGAPPPPPQR;DYEPPS(0.905)PS(0.095)PAPGAPPPPPQR 274.45 1.9809999999999995e-92 11343200.0 38048.0 27947.0 28029.0 23206.4 31977.0 32545.0 38775.0 30517.0 41865.0 41722.0 True False 37505.42854285136 27882.290438558568 25724.563815068854 24913.076070281004 30096.175729200873 31153.126216100445 40782.579772467885 31934.93122778574 37149.72284200591 48933.59210892949 0.7664556580960117 0.5697985624372456 0.5257035649008606 0.5091201155807815 0.6150412105901555 0.6366409019544584 0.8334270593028016 0.6526177591192655 0.7591865064659081 1.0 15.578537571323528 -8.709524050888145 0.4462734924699027 1.0165721296329568 0.5816866643553595 0.6400364209558501 0.08719682951915675 0.9611502057933194 0.44256820747890374 0.1375972086224581 0.06012785836903612 1.9519826317812214e-09 8.709524050888145 -0.4348854652775973 DYEPPSPS(ph)PAPGAPPPPPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DYEPPSPSPAPGAPPPPPQR 20 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-1;H0Y8L4 A8MQ02 MLLT4 Afadin 1 DYEPPS(0.17)PS(0.83)PAPGAPPPPPQR 147.49 0.00012719 6364100.0 22360.0 18574.0 18327.0 22685.0 31549.0 27532.0 27382.0 43861.0 29705.0 24741.0 True False 26145.10636986941 20417.903968710387 18763.98518553455 21414.032995762314 25367.199926391484 26088.173452684012 24788.17873148743 42709.69522457093 30139.37942866118 29226.347450351775 0.8945731728634028 0.698612921214164 0.6420229287087567 0.7326961753308168 0.8679565576739956 0.8926251731250806 0.8481449409166274 1.461342211753418 1.0312400302453264 1.0 14.834981919794064 -7.613247640208833 8.074292587769289 1.1835695645360846 0.7860558954232699 0.5937483761284998 0.13975159139465146 0.16003238891590998 12.553592966362181 0.06568921135789645 0.03774908868942323 2.436421144036402e-08 7.613247640208833 -0.3975136691128147 DYETATLSDIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DYETATLSDIK 11 0 O43707;O43707-2 O43707 ACTN4 Alpha-actinin-4 0 107.79 0.010440999999999999 3297200.0 18947.0 24641.0 18280.0 23743.0 24817.0 22015.0 24165.0 20937.0 18872.0 18901.0 False True 22154.35287969211 27087.19563330425 18715.864527286052 22412.75668584459 19954.287000325126 20860.49464480744 21875.916260550508 20387.425934585193 19147.967297683677 22327.601679766336 0.992240599659603 1.213170855598483 0.8382389114477394 1.0038138895211224 0.8937048988296872 0.934291776788171 0.9797700879075986 0.9131041581174675 0.8575917634286669 1.0 14.44654067188622 -5.265562021028994 24.999975176100314 0.9280796888055904 1.1027057272988676 0.48329539678600775 0.07243590460146175 247.47115451377624 1500690.2396091248 0.017427638066262883 0.03849215890907541 5.425477652569884e-06 5.265562021028994 0.17462603849327718 DYETATLSDIK ddPTM_PC-9_Lapatinib_30min_R1 2 DYETATLSDIK 11 0 O43707;O43707-2 O43707 ACTN4 Alpha-actinin-4 0 ; 140.78 0.00030253 21000500.0 70760.0 75842.0 86236.0 79277.0 81915.0 69916.0 80484.0 77415.0 75197.0 82449.0 False True 69750.94942420509 75666.39250871868 79146.00896058655 85107.29504031948 77096.92075108642 66925.85566215633 84651.06770876361 81011.98351735211 66727.52200048529 96700.19979361302 0.721311326895646 0.7824843451224843 0.8184678948906793 0.8801149865456717 0.7972777813865346 0.6920963535235295 0.8753970300933624 0.8377643861156003 0.6900453374750173 1.0 16.561231250026715 -11.001640353772919 5.517409380281226 1.0002752229467888 0.7931906207006891 0.48206313645434806 0.06564789614409561 0.00022416304596923348 2.117691408620162e-05 0.06411033610241602 0.01552856585285923 9.962300699520585e-12 11.001640353772919 -0.2070846022460997 DYETATLSEIK ddPTM_PC-9_Lapatinib_30min_R1 1 DYETATLSEIK 11 0 P12814-4;P12814-3;P12814;P12814-2;H9KV75;H7C5W8 P12814-4 ACTN1 Alpha-actinin-1 0 150.81 0.0015937000000000002 1698400.0 13751.0 18091.0 13966.0 14210.0 14373.0 15260.0 17112.0 16752.0 11682.0 10745.0 False True 13554.908218375442 18049.111401007736 12817.769390319025 15255.05080317038 13527.608398405231 14607.365372797434 17997.975630340963 17530.35907618268 10366.250143086418 12602.25893318747 1.0755935336861882 1.432212391182999 1.0171009386709249 1.2105012985407644 1.0734272696763034 1.1591069069632913 1.428154724145853 1.3910489515508435 0.8225707944936264 1.0 13.621394737053139 -8.270584125183557 24.826930789348147 0.9112853682991151 1.2227313871827938 0.4140334988894253 0.14851776018261684 663.5824912515809 1801526.5260685594 0.1372714371627912 0.037488915078447815 5.363099752431461e-09 8.270584125183557 0.31144601888367873 DYFEEYGK ddPTM_PC-9_AZD4547_30min_R2 3 DYFEEYGK 8 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;; 131.06 0.016422 74681000.0 160524.0 187469.0 191116.0 160570.0 166892.0 199432.0 188439.0 230010.0 191046.0 169819.0 False True 211567.29289337914 248064.68809389562 188581.67696702393 123553.06728177021 143721.92656561485 186961.48551319586 205209.7059452862 194467.2396039856 201144.30153186098 163873.68849888036 1.291038816733686 1.5137554440021679 1.1507745916655339 0.7539530501421182 0.877028691317928 1.1408877607247685 1.2522431625543613 1.1866898303525661 1.2274350042059086 1.0 17.32222470886564 -5.411922343095749 5.628740008259149 1.065466447542701 1.3968721207426957 0.4225888603628577 0.15625166584063765 0.23317101213875163 10.025377751921312 0.046417225484466466 0.09837452858269942 3.8732689728375245e-06 5.411922343095749 0.3314056731999948 DYFEEYGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 DYFEEYGK 8 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;;;; 139.88 0.012088 70822200.0 221177.0 325775.0 270640.0 235265.0 271229.0 191645.0 247676.0 202133.0 185481.9 170695.0 False True 258617.89765512603 358115.7890280292 277093.0840079159 222083.8647894217 218083.62448366755 181594.79882825885 224214.33626104318 196827.22292761633 188194.22189022021 201640.65227912314 1.2825682456984495 1.7760098719195956 1.3741925592679942 1.1013843799810756 1.0815459185372156 0.9005862497254987 1.1119500642691444 0.976128675953479 0.9333148834973537 1.0 17.62142700081963 -5.7297717463010125 2.6047550977646337 1.005304931037989 1.5399862566304876 0.7448973142925277 0.126770395856699 0.12157919853913515 1.6784315297316341 0.03499255508947943 0.06499510502430465 1.8630660576620486e-06 5.7297717463010125 0.5346813255924987 DYFEEYGK ddPTM_PC-9_Lapatinib_30min_R1 4 DYFEEYGK 8 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;;; 131.06 0.015219 154733000.0 232223.0 311540.0 322719.0 293297.0 335334.0 305153.0 332529.0 348094.0 283547.0 296965.0 False True 228911.45743551708 310818.64827096014 296186.2895513655 314867.03979011014 315610.3134120103 292102.31753638637 349745.72454310715 364267.7180196242 251610.95097772003 348295.0045690104 0.6572343973717862 0.8924005345858333 0.8503891404296032 0.9040239901796325 0.9061580248690474 0.8386635286309708 1.00416520465429 1.0458597259250928 0.722407578854225 1.0 18.409950255615257 -4.223086624190552 1.4082347378183744 0.9146277577932435 1.5915791216718194e-17 0.40990862557705865 0.08949858314229599 5.1638427484626765 3.0932773581881166 0.024860240554491146 9.855518506357322 5.98292248043819e-05 4.223086624190552 -0.9146277577932435 DYFEQYGK ddPTM_PC-9_AZD4547_30min_R2 4 DYFEQYGK 8 0 F8VZ49;Q32P51;F8VYN5;F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;A0A2R8Y4L2 F8VZ49;F8W6I7 HNRNPA1;HNRNPA1L2 Heterogeneous nuclear ribonucleoprotein A1-like 2;Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 0 ;;; 112.84 0.017156 99866000.0 245826.0 218093.0 305297.0 365184.0 347679.0 304645.0 278150.0 330066.0 293035.0 321206.0 False True 323993.55450155685 288587.2972089357 301248.5623024838 280996.4708365572 299409.77222638845 285595.499990811 302904.8111520514 279061.88386213355 308524.23185719096 309960.675707497 1.0452730939562875 0.9310448706121326 0.971892842906193 0.9065552273531864 0.9659605094839024 0.9213926874398775 0.9772362589565907 0.9003138324729878 0.9953657222903283 1.0 18.241725668773597 -8.4831202918376 24.699843030891632 1.0000001007761197 0.9508990511528433 0.1689134861098993 0.040072120397868505 602.879952733568 374538.26988785993 0.03586489737136908 0.00926027668318379 3.2876055744383946e-09 8.4831202918376 -0.04910104962327633 DYFEQYGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 DYFEQYGK 8 0 F8VZ49;Q32P51;F8VYN5;F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;A0A2R8Y4L2 F8VZ49;F8W6I7 HNRNPA1;HNRNPA1L2 Heterogeneous nuclear ribonucleoprotein A1-like 2;Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 0 ;;;; 112.84 0.017156 81854600.0 274822.0 295005.0 311563.0 338662.0 385193.0 299254.0 338461.0 310746.0 278012.0 250936.0 False True 321343.93661807873 324291.14677987545 318991.8435292573 319687.8660970177 309717.19678108714 283560.59343344124 306399.52383456234 302589.24676260207 282077.39955296856 296428.7103917171 1.0840513261803733 1.0939937172460097 1.0761165580342202 1.0784645848729184 1.0448286077681541 0.956589505310497 1.0336364633158146 1.020782522592849 0.951585962035243 1.0 18.177325660048908 -6.512430958648333 3.9383578018932512 0.9962355403397569 1.0823228021581763 0.7547827882691309 0.02430381012649617 0.1136597914218994 3.984251818193275 0.00812190392758041 0.008680582709619487 3.073045859561337e-07 6.512430958648333 0.08608726181841941 DYFEQYGK ddPTM_PC-9_Lapatinib_30min_R1 4 DYFEQYGK 8 0 F8VZ49;Q32P51;F8VYN5;F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;A0A2R8Y4L2 F8VZ49;F8W6I7 HNRNPA1;HNRNPA1L2 Heterogeneous nuclear ribonucleoprotein A1-like 2;Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 0 ;;; 134.91 0.016225999999999997 154213000.0 447228.0 418048.0 509691.0 439808.0 500042.0 411482.0 460620.0 391768.0 477558.0 381441.0 False True 440850.44670843007 417080.0355407927 467786.17344415555 472152.947476479 470630.51268039725 393883.8740713916 484468.649769031 409970.9714993996 423770.38913131837 447372.5686118163 0.9854212744343619 0.9322879067775199 1.0456299877654145 1.0553909215792006 1.0519878635848183 0.8804381441928848 1.0829198832470275 0.916397205066746 0.9472426761575149 1.0 18.771117272315784 DYFGAHTYELLAK ddPTM_PC-9_AZD4547_30min_R2 1 DYFGAHTYELLAK 13 0 P52209-2;P52209 P52209-2 PGD 6-phosphogluconate dehydrogenase, decarboxylating 0 64.65 0.034885 3484100.0 26344.0 33100.0 32632.0 35676.0 36438.0 34591.0 31143.0 45579.0 31885.0 32255.0 False True 34720.844010759705 43798.92769422117 32199.27835862998 27451.44938870545 31379.212665663243 32428.019301751727 33914.66666801481 38535.81285122421 33570.37600548236 31125.762267657905 1.115501805616416 1.4071600019811137 1.034489632149107 0.8819526780627521 1.0081427852537668 1.041838558776341 1.0896011598486954 1.238068083918572 1.078539883354587 1.0 14.925821548659606 -5.287052620107243 24.482058769577613 1.0491964642905267 1.2613309166831836 0.3947678125132986 0.10632259534774445 535.3698403644491 511725.1193582944 0.029468520508293763 0.06138407643054365 5.1635380288058545e-06 5.287052620107243 0.21213445239265694 DYFGAHTYELLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DYFGAHTYELLAK 13 0 P52209-2;P52209 P52209-2 PGD 6-phosphogluconate dehydrogenase, decarboxylating 0 ; 136.38 3.1978000000000005e-05 3713400.0 68929.0 86154.0 75703.0 70507.0 74312.0 53401.0 69407.0 55972.0 47929.0 57450.0 False True 80597.31829019375 94706.79974804992 77508.04662522628 66556.72137677808 59751.09705315555 50600.557552912185 62832.26649683546 54502.794307236116 48629.87095224039 67865.23022605016 1.187608411873572 1.3955128337823952 1.1420877283854658 0.9807190096473023 0.8804375503351642 0.7456035643637895 0.9258388468962595 0.803103358313152 0.7165653279339167 1.0 16.050384999259634 -5.793788843388022 1.7456221195020072 0.8331050478757426 1.2958799532710987 0.7901933352112029 0.09284372844201469 0.14392370405737812 0.8942257293267171 0.028253347794034118 0.05729365288567188 1.6077227475677517e-06 5.793788843388022 0.46277490539535615 DYFGAHTYELLAK ddPTM_PC-9_Lapatinib_30min_R1 2 DYFGAHTYELLAK 13 0 P52209-2;P52209 P52209-2 PGD 6-phosphogluconate dehydrogenase, decarboxylating 0 ; 131.17 6.0057e-05 9323200.0 101753.0 97875.0 108472.0 97773.0 102397.0 98578.0 116524.0 109183.0 99901.0 121802.0 False True 100301.98356078536 97648.37645092221 99553.85087402885 104963.55258116667 96374.20978024766 94362.04873654178 122557.04256368932 114256.04077213781 88649.09737583253 142855.31340903678 0.7021228764070628 0.6835473887577859 0.6968858805340821 0.7347542774319157 0.674628107841533 0.6605428001572156 0.8579102844622409 0.7998025277855025 0.620551628499838 1.0 17.1241951717983 -14.52287874514831 0.248552874931867 2.683087876268714 0.6926841023980357 0.6170381799527271 0.06675074228169048 123.24139194270141 1.2208340323067652 105.39704731688091 0.09956020643427756 3.0000000009120165e-15 14.52287874514831 -1.9904037738706784 DYGHSSSRDDYPSR ddPTM_PC-9_AZD4547_30min_R2 2 DYGHSSSRDDYPSR 14 1 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 0 ; 118.76 4.9976000000000004e-05 14755100.0 10582.3 6654.099999999999 36343.0 163688.0 82813.0 36889.0 15465.9 49684.0 18663.0 42302.0 False True 13947.251274486116 8804.907696982382 35861.068073905626 125952.2605543899 71315.84440643211 34582.32499847703 16842.33513858172 42006.479424739984 19649.488078730363 40821.019855726714 0.3416683689868537 0.2156954365202406 0.878495152758285 3.0854755956500255 1.7470373023134385 0.8471695494306846 0.41258976865613356 1.029040420185557 0.4813571083764525 1.0 15.317024606075385 -6.97708886854225 22.92426778255165 0.7184114199619113 1.278949977602423 0.09550315807354959 0.7731439574184106 244.93757276931 245075.07807983804 0.3082567275758592 0.27182747484513453 1.0541711620358205e-07 6.97708886854225 0.5605385576405116 DYGHSSSRDDYPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DYGHSSSRDDYPSR 14 1 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 0 75.483 0.0078523 3843700.0 6663.2 3176.5 11495.0 16026.0 19841.0 28482.0 13991.0 19780.0 20993.0 14036.0 False True 7791.148155801154 3491.841927242845 11769.084395030255 15128.11517699303 15953.298479810244 26988.353780304573 12665.671193931801 19260.795958642375 21299.982910145896 16580.615691085142 0.46989498465911617 0.21059784463373665 0.7098098535242034 0.9123976732134818 0.9621656262371375 1.6277051638568123 0.7638842507363415 1.1616454007192434 1.2846316027696247 1.0 14.017209959240965 -5.693939729375505 1.5275531109329126 1.1468513142986878 0.3233762933159436 0.6571590453139562 0.22479044097108905 0.24137642087933067 1.1242842586705433 0.0711309923996508 0.17568595560823502 2.023299949204393e-06 5.693939729375505 -0.8234750209827442 DYGHSSSRDDYPSR ddPTM_PC-9_Lapatinib_30min_R1 1 DYGHSSSRDDYPSR 14 1 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 0 115.37 7.2079e-05 2825300.0 27873.0 7020.2 24720.0 8791.1 13172.0 17573.0 7902.0 5691.5 24442.0 8899.0 False True 27475.5259087178 7003.9451582198 22687.617021959475 9437.626820249909 12397.248857148385 16821.443754663782 8311.126895217052 5955.94786784227 21689.084574329572 10437.18029282786 2.632466349900865 0.6710572167688543 2.1737304890239155 0.9042314643865244 1.1877967525067503 1.6116846967013698 0.7963000218486431 0.5706472151233253 2.0780597791564173 1.0 13.349444385805269 -4.7469513401178105 24.996415987610266 1.2257785779855346 2.632469988791642 0.3858932603045958 0.5339565707857018 803.520882524387 1386247.7125789537 0.1263915669484109 2.727796528171418 1.7908064910567896e-05 4.7469513401178105 1.4066914108061073 DYGNS(ph)PLHR ddPTM_PC-9_AZD4547_30min_R2 1 DYGNSPLHR 9 0 A6NLN1;P26599;P26599-2;P26599-3;A0A0D9SF20;A0A087WUW5;K7ELW5;A0A0U1RRM4 A6NLN1;A0A0U1RRM4 PTBP1 Polypyrimidine tract-binding protein 1 1 DYGNS(1)PLHR 68.46300000000001 0.024363 4715600.0 18063.0 20983.0 29640.0 29668.0 34205.0 27768.0 25711.0 33178.0 20359.0 27838.0 True False 23806.658266259958 27765.344405070784 29246.95423356803 22828.50096603077 29456.22617127753 26031.66257035187 27999.22919119317 28051.102454593485 21435.13517627774 26863.40009322776 0.8862116553988114 1.033575210461553 1.0887286840857187 0.8497993882682712 1.0965189093358074 0.9690382632135397 1.0422816580933012 1.0442126595011756 0.7979308316106092 1.0 14.713354297389788 -8.238507514823477 24.96991945247059 0.8989653481875166 1.0037013807337425 0.17462109921371172 0.0888672938650539 1079.9463489491216 1175929.7701925773 0.05636651868794318 0.021274435126061836 5.774208812134786e-09 8.238507514823477 0.10473603254622588 DYGNS(ph)PLHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DYGNSPLHR 9 0 A6NLN1;P26599;P26599-2;P26599-3;A0A0D9SF20;A0A087WUW5;K7ELW5;A0A0U1RRM4 A6NLN1;A0A0U1RRM4 PTBP1 Polypyrimidine tract-binding protein 1 1 DYGNS(1)PLHR;DYGNS(1)PLHR 78.964 0.011807999999999999 7594300.0 57520.0 64984.0 73508.0 75867.0 88267.0 73856.0 73348.0 55564.0 53808.0 48527.0 True False 67256.99992821515 71435.18205570572 75260.70950064255 71616.41795413267 70971.71497996117 69982.86134394276 66399.9464464662 54105.50387492441 54594.84020526515 57324.560960479335 1.1732667254893314 1.246153147251394 1.3128876739680353 1.2493147222445615 1.2380681821338404 1.2208180956185657 1.1583158306653865 0.943845063414019 0.9523813055088881 1.0 15.806865780030359 -7.622500294812239 2.8704823217742286 0.9576962206671068 1.2429168375597939 0.9179482167570167 0.036579325958249344 0.0706569770469378 1.167368238617657 0.021652089374053073 0.011145698689160875 2.3850621764121618e-08 7.622500294812239 0.2852206168926871 DYGNS(ph)PLHR ddPTM_PC-9_Lapatinib_30min_R1 1 DYGNSPLHR 9 0 A6NLN1;P26599;P26599-2;P26599-3;A0A0D9SF20;A0A087WUW5;K7ELW5;A0A0U1RRM4 A6NLN1;A0A0U1RRM4 PTBP1 Polypyrimidine tract-binding protein 1 1 DYGNS(1)PLHR 85.973 0.0068131 3549900.0 31256.0 39230.0 43826.0 37185.0 40427.0 36451.0 24931.0 23815.0 31375.0 28015.0 True False 30810.283708351595 39139.16534528402 40222.79545325229 39919.708945523635 38049.16334254004 34892.07570143116 26221.80519168011 24921.53184093185 27841.217106603006 32857.355422358974 0.9376982204534217 1.1911842825503345 1.224164115955639 1.2149398036568344 1.1580105231673063 1.0619258687413287 0.7980497777321583 0.7584764969846932 0.84733590846625 1.0 15.003928746855546 -7.119403310538069 3.442909586412159 0.8309257437359889 1.153807853567384 0.6727952447068735 0.09647106259210493 0.13891983430675636 3.0329719337515537 0.039454068610512004 0.02999831600165111 7.596205225005015e-08 7.119403310538069 0.322882109831395 DYGNSPLHR ddPTM_PC-9_AZD4547_30min_R2 2 DYGNSPLHR 9 0 A6NLN1;P26599;P26599-2;P26599-3;A0A0D9SF20;A0A087WUW5;K7ELW5;A0A0U1RRM4 A6NLN1;A0A0U1RRM4 PTBP1 Polypyrimidine tract-binding protein 1 0 ; 99.815 0.0033738 22024900.0 15901.7 16531.1 106511.0 229409.0 155475.0 118123.0 48867.0 152313.0 77878.0 109833.0 False True 20958.109824092673 21874.454791720233 105098.59454694882 176522.29938371805 133889.9799438493 110736.75013676439 53216.06833207721 128776.52565454492 81994.47208891198 105987.78010056344 0.19774081317871905 0.20638657372543598 0.9916104898812774 1.6654967130760732 1.2632586494104476 1.044806769532252 0.5020962631879324 1.2150129527419014 0.7736219402945688 1.0 16.693538412766955 -5.277230277618813 5.327252761361922 1.0769223656783464 0.19295299052828563 0.5847027953907713 0.28842677988494003 0.11668211332331992 11.169050443342064 0.08122320196241979 0.18993482321461067 5.281651265072323e-06 5.277230277618813 -0.8839693751500608 DYGNSPLHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DYGNSPLHR 9 0 A6NLN1;P26599;P26599-2;P26599-3;A0A0D9SF20;A0A087WUW5;K7ELW5;A0A0U1RRM4 A6NLN1;A0A0U1RRM4 PTBP1 Polypyrimidine tract-binding protein 1 0 ;; 132.88 0.00099665 11569700.0 29968.5 31899.8 99817.0 92489.0 135053.0 119432.0 91976.0 82404.0 103721.0 58423.0 False True 35041.5751451445 35066.60132556628 102197.01583808071 87307.1411833839 108590.33413607237 113168.77567197998 83263.36743142543 80240.98231425509 105237.72340414638 69014.62742378654 0.5077412782361423 0.5081038996304172 1.4808022538546306 1.2650527061063677 1.5734394024801428 1.6397795640779667 1.2064597106370514 1.1626663116143878 1.524861139333996 1.0 16.074614548327986 -5.25700192692542 24.90738667893024 1.3716636138466998 0.5079224676804662 0.7574597053003302 0.19195113865224556 156.7951982375983 880081.6434259611 0.049301222890662494 0.12132265303096809 5.5334765405669036e-06 5.25700192692542 -0.8637411461662335 DYGNSPLHR ddPTM_PC-9_Lapatinib_30min_R1 3 DYGNSPLHR 9 0 A6NLN1;P26599;P26599-2;P26599-3;A0A0D9SF20;A0A087WUW5;K7ELW5;A0A0U1RRM4 A6NLN1;A0A0U1RRM4 PTBP1 Polypyrimidine tract-binding protein 1 0 ;; 123.86 0.0012399000000000002 17513200.0 81335.0 78311.0 204577.0 103770.0 172426.0 213205.0 130404.0 127819.0 231261.0 87505.0 False True 80175.14798498758 78129.67569091334 187757.4687500566 111401.59196657223 162284.24168255882 204086.71915512948 137155.6810483277 133757.93736620038 205213.95089370897 102630.12265691653 0.7812048345007444 0.7612743088312772 1.8294577058795234 1.085466811132809 1.5812535099958982 1.9885654803061419 1.3364076500895072 1.3033009598297118 1.999548919762292 1.0 16.6470947085937 -5.246475386712793 24.099918020944017 1.5238213319913594 0.7712392828509839 0.44841443549036497 0.330077450952461 430.5136860187206 693348.9257514576 0.080819342762638 0.2116992396148184 5.669237005532454e-06 5.246475386712793 -0.7525820491403755 DYGVLLEGSGLALR ddPTM_PC-9_Lapatinib_30min_R1 2 DYGVLLEGSGLALR 14 0 P30048-2;P30048 P30048-2 PRDX3 Thioredoxin-dependent peroxide reductase, mitochondrial 0 ; 127.52 0.00013148 6219200.0 26314.0 30455.0 28266.0 24978.0 25556.0 25704.0 28155.0 24240.0 25781.0 24412.0 False True 25938.757534603392 30384.483318649618 25942.07858991531 26814.965444165362 24052.846325029168 24604.69983895056 29612.72813652699 25366.278892470633 22877.27229403449 28631.581673054672 0.9059491658825991 1.0612226619406293 0.9060651586122304 0.9365520127517462 0.8400809497599437 0.8593552434480478 1.0342679798369532 0.8859545093292197 0.7990223018508408 1.0 14.805319749811384 -5.438431894137762 21.66742397235853 0.9049220417196098 0.9836030750546162 0.13917935916333735 0.07528665042830432 45.630291898563634 11704.900753133292 0.019466966934806474 0.04052367697931823 3.6439138927929655e-06 5.438431894137762 0.07868103333500642 DYHFVTSR ddPTM_PC-9_AZD4547_30min_R2 1 DYHFVTSR 8 0 Q12959-3;Q12959;Q12959-5;A0A590UK48;Q12959-8;A0A590UJX2;A0A590UJS9;A0A590UJ68;A0A590UJ18;Q12959-9;Q12959-6;A0A590UJ08;A0A590UJR5;A0A590UJC5;A0A590UKA8;A0A0C4DFT3;A0A590UJD9;A0A590UJR4;A0A590UJ81;C9JUA9;Q12959-7;Q12959-2;Q12959-4;A0A590UK81;A0A590UJ29 Q12959-3 DLG1 Disks large homolog 1 0 93.14299999999999 0.008435600000000001 0.0 8404.4 7005.6 13296.0 21944.0 14744.0 15644.0 10229.0 19967.0 13263.0 13106.0 False True 11076.824377620285 9270.023198025247 13119.686352547935 16885.149831420345 12697.05009996539 14665.778206949906 11139.361183801297 16881.558946014473 13964.05510304885 12647.162929155937 0.8758347180049767 0.7329725449060789 1.0373620096490315 1.3350938804223382 1.0039445345243752 1.159610126721811 0.8807794480231884 1.3348099522855705 1.1041255008154467 1.0 13.626526168651907 -5.398864450928955 4.907004702195081 1.122458740227454 0.8084238679284311 0.4408934208060007 0.13817307584033198 0.18501105631135528 6.533760201911008 0.035268584214162214 0.07590885556042191 3.991494627668387e-06 5.398864450928955 -0.3140348722990228 DYHQQFR ddPTM_PC-9_AZD4547_30min_R2 1 DYHQQFR 7 0 A0A6I8PIQ6;A0A0A0MS45;J3KNI1;Q9H9E3-3;Q9H9E3 A0A6I8PIQ6 COG4 Conserved oligomeric Golgi complex subunit 4 0 87.75399999999999 0.007800399999999999 0.0 6324.9 5787.5 8001.4 9482.3 10185.0 6858.6 5351.1 7654.8 4542.8 6450.6 False True 8336.0866339073 7658.196194269032 7895.296207978117 7296.3022350746105 8770.98855589714 6429.730657772093 5827.337533545714 6471.926549804761 4782.9231336899875 6224.766457409832 1.3391806248384142 1.2302784765768804 1.2683682612027511 1.1721407196553126 1.4090470085759343 1.032927211288108 0.9361536008485866 1.039705922155636 0.7683698924955644 1.0 12.603803995407926 -6.92058466730915 5.463365641365316 0.9449818027521544 1.272716285198777 0.7775894015773201 0.08877592437385651 0.09490697797593166 4.841559615472531 0.030404639346820757 0.02668365853432945 1.20064697964497e-07 6.92058466730915 0.3277344824466226 DYHQQFR ddPTM_PC-9_Lapatinib_30min_R1 1 DYHQQFR 7 0 A0A6I8PIQ6;A0A0A0MS45;J3KNI1;Q9H9E3-3;Q9H9E3 A0A6I8PIQ6 COG4 Conserved oligomeric Golgi complex subunit 4 0 94.006 0.0062089 0.0 7867.0 6080.2 7226.5 8027.3 7885.6 7450.2 6051.1 6896.7 6885.1 5265.4 False True 7754.815137368889 6066.121670466371 6632.365065096691 8617.654420287798 7421.784511686099 7131.5723132644525 6364.39634974031 7217.145859641184 6109.627534682788 6175.517374295513 1.2557352959036145 0.982285580754014 1.0739772335031759 1.3954546474368679 1.2018077291107543 1.1548137396468752 1.0305851257468681 1.1686706428324958 0.989330474579024 1.0 12.59234429294854 -7.151561820028195 4.886459108182977 1.061546637865684 1.1766725926479331 0.2438533657984523 0.11164651923633914 0.4223614001885454 15.487855401081887 0.04619131554763124 0.035444223944940685 7.054044254933022e-08 7.151561820028195 0.11512595478224918 DYIPVDQEELR ddPTM_PC-9_AZD4547_30min_R2 1 DYIPVDQEELR 11 0 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 95.48299999999999 0.028567000000000002 4928500.0 24161.0 19649.0 20802.0 29274.0 23342.0 30351.0 33948.0 29415.0 28499.0 30943.0 False True 31843.69541998046 26000.154992862597 20526.151888214652 22525.331578791436 20101.366212248508 28453.147172023535 36969.30623400978 24869.587639455898 30005.39895813837 29859.694988316205 1.0664440957096373 0.8707441587409447 0.6874200120344942 0.7543724605226333 0.6731939566065215 0.9528947694595328 1.2381005984312798 0.8328815029486106 1.00487962016622 1.0 14.865911808213763 -6.973877083347617 13.711167489743886 1.017957039591857 0.8047288926547791 0.34227132403445826 0.13771750312225106 1.8683605208994671 978.560584325259 0.050420659008897716 0.04440868549513861 1.0619960872270372e-07 6.973877083347617 -0.2132281469370778 DYIPVDQEELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DYIPVDQEELR 11 0 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ; 141.91 0.00062557 8267200.0 33985.0 33366.0 36074.0 36872.0 34598.0 33770.0 36030.0 29665.0 25738.0 24429.0 False True 39737.98926565349 36678.35597178804 36934.14097140686 34806.181380636874 27818.77026382112 31999.041751312605 32616.977565389378 28886.325182665612 26114.369558487848 28857.784320142386 1.3770284241093607 1.271003884597855 1.2798675241892106 1.2061279894015486 0.9639953627487594 1.1088530358506303 1.1302661771792064 1.0009890178056153 0.9049332848558416 1.0 14.816672914546473 -5.435565864536703 0.45339336562083277 0.9747412974175792 1.5165398984110448 0.7903932394549363 0.06806728945776833 1.38988116322944 0.3418674021351279 0.05740021820057014 0.3815833449714279 3.668040611956046e-06 5.435565864536703 0.5417986009934656 DYIPVDQEELR ddPTM_PC-9_Lapatinib_30min_R1 2 DYIPVDQEELR 11 0 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ; 161.67 0.0042691000000000005 11648900.0 67058.0 60985.0 55222.0 53507.0 57368.0 59203.0 47658.0 51823.0 57039.0 42626.0 False True 66101.74062306902 60843.79297940723 50681.86032308442 57442.0832741195 53993.72702982755 56671.02569893363 50125.49804761505 54230.8857691628 50614.667172702124 49993.84730442525 1.3221975140372517 1.2170256193509954 1.0137619538354325 1.1489830523412219 1.080007439736454 1.1335600029709523 1.0026333389064488 1.0847511982612008 1.0124179254398353 1.0 15.609462934245204 -1.5228787458627304 0.6518975240330829 1.0537169519462732 26.248281151693362 0.711263665536668 0.05421269557676297 118.6654424013147 0.7604670895786652 0.02218091762583908 4316.484227172158 0.029999999959769725 1.5228787458627304 25.194564199747088 DYLEDQQGGREFWPQEVWSRY(ph)VKK ddPTM_PC-9_Lapatinib_30min_R1 1 DYLEDQQGGREFWPQEVWSRYVKK 24 3 E9PNM1;A0A1W2PQ47;P37268-4;P37268-3;P37268-2;P37268-5;P37268 E9PNM1 FDFT1 Squalene synthase 1 DY(0.001)LEDQQGGREFWPQEVWS(0.167)RY(0.832)VKK 46.982 0.021928 5046200.0 1259.7 2143.6 1571.7 1495.8 1891.6 1440.0 751.53 1527.5 2418.9 1780.9 True False 1241.7364469993126 2138.6366259023907 1442.4808929374478 1605.8061218425248 1780.3398070286887 1378.4145568039517 790.4405461354686 1598.4732264129082 2146.4580098537704 2088.726192099914 0.5944946023542345 1.023895153893914 0.6906031524827295 0.768796852318933 0.8523567204559315 0.6599307089734696 0.3784318639394253 0.7652861502186044 1.0276397250976277 1.0 11.028407668790495 -8.220505380870362 5.282143840839986 1.0158073021230696 0.7176122855403925 0.36259557764864725 0.15821484317198534 0.2106513467318546 15.032298205119492 0.1237105154450668 0.04248527119645976 6.0185880587580686e-09 8.220505380870362 -0.2981950165826771 DYLHLPPEIVPATLR ddPTM_PC-9_AZD4547_30min_R2 1 DYLHLPPEIVPATLR 15 0 P46783;F6U211;A0A2R8Y7H1;S4R435;A0A2R8YFH6;A0A1W2PQS6;A0A2R8Y6L3 P46783 RPS10;RPS10-NUDT3 40S ribosomal protein S10 0 79.81 0.008804000000000001 3034300.0 7956.6 10090.0 12309.0 13562.0 10568.0 12163.0 13261.0 15240.0 10493.0 13221.0 False True 10486.63329243891 13351.395179295816 12145.774617442275 10435.49043081129 9100.815616958374 11402.445687236745 14441.203310038996 12885.008180360634 11047.638558115928 12758.13681415921 0.8219564851194145 1.046500392163705 0.952002223707358 0.8179478385299799 0.7133342234469633 0.8937390979051193 1.131921025804637 1.0099443490887023 0.8659288357728739 1.0 13.639130034260358 -7.030670514374547 24.339759662985294 1.0042134028334062 0.8739373632163946 0.27727149087379765 0.10148141870937688 734.7974849593913 583124.2797147413 0.04194685060690519 0.03254007157139838 9.318145458899828e-08 7.030670514374547 -0.13027603961701162 DYLHLPPEIVPATLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DYLHLPPEIVPATLR 15 0 P46783;F6U211;A0A2R8Y7H1;S4R435;A0A2R8YFH6;A0A1W2PQS6;A0A2R8Y6L3 P46783 RPS10;RPS10-NUDT3 40S ribosomal protein S10 0 73.02199999999999 0.037074 0.0 10926.0 13991.0 14387.0 12080.0 17243.0 15620.0 15232.0 14652.0 12409.0 12297.0 False True 12775.556001663374 15379.934016702226 14730.04064300133 11403.19676388842 13864.357929911186 14800.859702561533 13789.114689869852 14267.400525077252 12590.458149478423 14526.348757001564 0.8794746853028484 1.058761170751132 1.0140222356909605 0.7850008942124693 0.9544282711255088 1.0188974497412955 0.9492484946173159 0.9821738940558272 0.8667324707738371 1.0 13.826384502194733 -6.514952827243172 24.931255610509584 0.9642169479570751 0.9389993544530485 0.02847866017339795 0.07845390445052973 2076.5441623298975 6531863.872079516 0.02636653357936576 0.027474099431241662 3.055252954589518e-07 6.514952827243172 -0.025217593504026636 DYLHLPPEIVPATLR ddPTM_PC-9_Lapatinib_30min_R1 2 DYLHLPPEIVPATLR 15 0 P46783;F6U211;A0A2R8Y7H1;S4R435;A0A2R8YFH6;A0A1W2PQS6;A0A2R8Y6L3 P46783 RPS10;RPS10-NUDT3 40S ribosomal protein S10 0 ; 82.102 0.006832600000000001 4521800.0 20287.9 28652.0 28926.0 25562.0 26370.0 28412.0 24492.0 27691.0 23996.0 25499.0 False True 19998.590825654803 28585.65805437365 26547.815937589003 27441.91475233225 24818.96844541473 27196.884991606872 25760.075919723615 28977.624950965514 21293.31779091779 29906.468174718222 0.6687045327057657 0.9558353024961626 0.8876947883813143 0.9175912913558475 0.8298863075512116 0.90939808849104 0.8613546664630962 0.9689417279791696 0.7119970725569775 1.0 14.868169923986095 DYLHYIR ddPTM_PC-9_AZD4547_30min_R2 2 DYLHYIR 7 0 P62280;M0R1H5;M0QZC5 P62280 RPS11 40S ribosomal protein S11 0 ; 110.34 0.0079563 19743500.0 126480.0 142785.0 159326.0 213526.0 174453.0 177753.0 207396.0 247296.0 177293.0 187995.0 False True 166698.0090525694 188937.4589371411 157213.233138241 164300.87964381446 150233.2122279747 166638.07681027672 225853.84222071152 209082.08549674903 186664.3460291667 181413.35227122495 0.9188850046899792 1.041474933193821 0.8666023265101062 0.9056713719625984 0.828126542766081 0.9185546417837083 1.2449681315796706 1.1525176227610716 1.0289449133274997 1.0 17.46892111854229 -7.228820897032606 20.02741289685967 1.1193171791823413 0.9127185495714858 0.5771879711661613 0.08079395942581406 40.41923547937756 24816.675442472973 0.031444359311385874 0.024348998208987904 5.904445291884577e-08 7.228820897032606 -0.2065986296108555 DYLHYIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DYLHYIR 7 0 P62280;M0R1H5;M0QZC5 P62280 RPS11 40S ribosomal protein S11 0 ; 118.69 0.005720899999999999 9696300.0 106592.0 105889.0 132013.0 133500.0 177977.0 127109.0 127053.0 147886.0 120838.0 88240.0 False True 124635.9203120356 116400.96012397813 135160.69058209052 126020.42781283942 143103.68446858483 120443.1802773941 115017.62005593722 144004.14919816924 122605.02714696382 104237.21349254441 1.195695051086052 1.116692937424922 1.2966644641911684 1.2089773276782103 1.3728655983193598 1.155471987804133 1.1034218606022492 1.381504209228206 1.1762116718107893 1.0 16.669510897317544 DYLHYIR ddPTM_PC-9_Lapatinib_30min_R1 2 DYLHYIR 7 0 P62280;M0R1H5;M0QZC5 P62280 RPS11 40S ribosomal protein S11 0 ; 97.473 0.010468 14208500.0 127388.0 112185.0 131022.0 132259.0 145405.0 146021.0 131468.0 122943.0 149956.0 128058.0 False True 125571.4237599017 111925.24252512596 120249.87691954568 141985.7680630899 136852.5637772291 139776.02222157622 138274.7697621357 128655.38060548744 133066.37617331505 150192.65467344105 0.8360690077216327 0.7452111607487152 0.8006375357103916 0.9453576033515413 0.9111801377689417 0.9306448609320251 0.9206493490828961 0.8566023477327743 0.8859712644578851 1.0 17.196454732526504 -5.713032015105181 7.1157883414958105 0.9153758470455308 0.7878277664578615 0.666392701567027 0.04114113073645831 0.12467231869672647 14.517687115662314 0.011024323173046385 0.019019970863941773 1.93627922101424e-06 5.713032015105181 -0.1275480805876693 DYLLCDYNR ddPTM_PC-9_AZD4547_30min_R2 3 DYLLCDYNR 9 0 B1AK87;B1AK85;B1AK88;P47756-2;P47756;A0A6I8PRV6 B1AK87 CAPZB F-actin-capping protein subunit beta 0 ;; 105.1 0.01225 27172000.0 77990.0 77854.0 114019.0 138325.0 128345.0 107681.0 99113.0 129945.0 102761.0 107833.0 False True 102789.19770722555 103018.78298205131 112507.03356130884 106436.30834994632 110526.51214596142 100947.69004746687 107933.86499267754 109864.98608903938 108192.73666926063 104057.7994918108 0.987808681417628 0.9900150059406047 1.0811975086035044 1.0228575740574133 1.062164611261645 0.9701117123412869 1.0372491588309225 1.0558073169487463 1.0397369269544783 1.0 16.667025578543672 -5.057233899818308 24.92687404657699 1.0342259337607789 0.9883601070681342 0.26440792535595814 0.029839164168199678 295.52042241498435 128706.63350285008 0.007452756989612734 0.019718261769180893 8.76528618266955e-06 5.057233899818308 -0.04586582669264472 DYLLCDYNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DYLLCDYNR 9 0 B1AK87;B1AK85;B1AK88;P47756-2;P47756;A0A6I8PRV6 B1AK87 CAPZB F-actin-capping protein subunit beta 0 110.41 0.010615000000000001 6740000.0 23880.0 35157.0 33954.0 37100.0 41720.0 25278.0 32935.0 22257.0 28159.0 25914.0 False True 27922.412348500966 38647.15461548141 34763.59213126206 35021.40727982285 33545.26548952588 23952.377180624244 29815.158371248945 21672.7773332408 28570.77210340582 30612.003064888853 0.9121393425093186 1.262483690909095 1.1356196475471731 1.144041675599839 1.0958206628432428 0.7824505024990337 0.9739695343702004 0.7079829858667072 0.9333192618217044 1.0 14.901809828766975 -6.691107336756259 6.771430057737652 0.8676156939555417 1.1239746943910396 0.5009068906548408 0.11443709616916467 0.16007203475545087 12.380929122676337 0.0358507327309229 0.03566651396986078 2.0365386808621274e-07 6.691107336756259 0.25635900043549786 DYLLCDYNR ddPTM_PC-9_Lapatinib_30min_R1 2 DYLLCDYNR 9 0 B1AK87;B1AK85;B1AK88;P47756-2;P47756;A0A6I8PRV6 B1AK87 CAPZB F-actin-capping protein subunit beta 0 ; 134.77 0.0050525 18125400.0 56557.0 75585.0 81448.0 67507.0 79845.0 77353.0 67011.0 75553.0 85666.0 65434.0 False True 55750.486808716465 75409.98757642873 74751.65983837188 72471.68997675023 75148.67408130973 74044.79250865002 70480.50169265886 79063.468199787 76017.39297702794 76744.17971467554 0.7264457971404374 0.9826150707036395 0.9740368600757533 0.9443281594277266 0.9792100763953998 0.9648261638073209 0.9183823705549503 1.0302210342691038 0.9905297477886962 1.0 16.227769720062536 -4.760208716300632 24.99299244739824 0.9738579237776325 0.7264454991215032 0.8712913525338674 0.028765681542852254 10.334289920749828 209788.89794182475 0.007248487642772277 0.043616405783966486 1.7369658648411218e-05 4.760208716300632 -0.24741242465612923 DYNASASTIS(ph)PPSSMEEDKFSR ddPTM_PC-9_AZD4547_30min_R2 2 DYNASASTISPPSSMEEDKFSR 22 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DYNAS(0.001)AS(0.033)T(0.033)IS(0.926)PPS(0.005)S(0.002)MEEDKFSR;DYNASAST(0.002)IS(0.997)PPSSMEEDKFSR 96.41 7.1018e-05 16275200.0 26400.1 32672.4 36025.0 25985.9 31978.0 37896.0 38580.0 37698.0 38205.0 33777.2 True False 34794.7826438072 43233.114356394886 35547.284961683145 19995.252233152845 27538.406680459386 35526.35712928749 42013.545260636776 31872.64031386057 40224.43830294668 32594.67050897953 1.0674991371433424 1.3263859913688825 1.0905858045685781 0.6134515833698745 0.84487452244295 1.0899437415543227 1.2889697795552937 0.9778482131021988 1.2340802246141809 1.0 14.992348471035733 -9.141351972368321 16.169297611325344 1.0000006508056616 1.0539110773274043 0.0070612701333572225 0.202057052388644 134537188.81829774 0.0 0.21275881497746338 0.05318970374436587 7.22184274770427e-10 9.141351972368321 0.053910426521742716 DYNASASTIS(ph)PPSSMEEDKFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DYNASASTISPPSSMEEDKFSR 22 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DYNAS(0.005)AS(0.025)T(0.054)IS(0.892)PPS(0.011)S(0.011)MEEDKFS(0.001)R;DYNAS(0.001)AS(0.005)T(0.011)IS(0.517)PPS(0.188)S(0.188)MEEDKFS(0.089)R 52.577 0.036258 121272000.0 87664.0 155493.0 118687.0 125902.0 102805.0 79810.0 104500.0 66094.0 75518.0 71980.0 True False 102503.7837570766 170929.3174225632 121516.9482029538 118848.11911979143 82661.09824186734 75624.62310252473 94601.00348551727 64359.10253238162 76622.30788398026 85029.40420663336 1.205509843488707 2.010237740901736 1.4291167783282428 1.3977296469227733 0.9721472120513662 0.8893937786362268 1.1125681094462756 0.756904074924246 0.9011271876935338 1.0 16.375674208650885 -6.110350870160895 1.9136537549576 0.9209007266181923 1.6049663547276756 0.6551196147187968 0.20505763594549886 0.1903983345943729 1.3805636918517374 0.0653597352992216 0.09613385619750693 7.756202333273393e-07 6.110350870160895 0.6840656281094832 DYNASASTIS(ph)PPSSMEEDKFSR ddPTM_PC-9_Lapatinib_30min_R1 4 DYNASASTISPPSSMEEDKFSR 22 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DYNASAS(0.002)T(0.005)IS(0.991)PPS(0.001)SMEEDKFSR;DYNASAS(0.001)T(0.014)IS(0.969)PPS(0.011)S(0.005)MEEDKFSR;DY(0.001)NAS(0.011)AS(0.05)T(0.015)IS(0.911)PPS(0.009)S(0.003)MEEDKFS(0.001)R;DYNAS(0.002)AS(0.009)T(0.017)IS(0.32)PPS(0.291)S(0.13)MEEDKFS(0.231)R 87.49600000000001 0.00010284 45592000.0 28743.6 58045.0 54661.3 52066.0 60351.0 56480.0 52017.1 62695.0 55282.3 56357.0 True False 28333.71099306932 57910.60036877416 50167.258912719815 55895.107327084406 56801.272834631214 54064.48206131057 54710.290916374935 65608.03857935013 49055.82522557322 66098.2323590177 0.42866064616028704 0.8761293351118412 0.7589803406577114 0.8456369456823865 0.8593463214887606 0.8179414203946502 0.8277118610254466 0.9925838594744102 0.7421654630508526 1.0 16.012324070329647 -4.759456012780188 24.99992845260144 0.8519902519627419 0.4286601095443371 0.7185456324770287 0.08050573299378751 26.262957862178318 330953.90637225215 0.018659055168984837 0.11832358686997631 1.7399789216898113e-05 4.759456012780188 -0.42333014241840483 DYNASASTISPPS(ph)SMEEDKFSR ddPTM_PC-9_AZD4547_30min_R2 1 DYNASASTISPPSSMEEDKFSR 22 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 DYNAS(0.001)AS(0.003)T(0.006)IS(0.09)PPS(0.445)S(0.445)MEEDKFS(0.011)R 53.278 0.030042000000000003 74278000.0 22082.0 25952.0 27896.0 20959.0 25152.0 33015.0 27980.0 33632.0 29901.0 26970.0 True False 29103.616665866844 34340.47648097969 27526.080813077388 16127.226363322063 21660.078955122714 30950.5668308905 30470.165795557747 28434.947186475612 31481.505815898665 26025.7885090291 1.1182607072892319 1.3194788111440308 1.0576463726940606 0.6196633142441414 0.8322544751183314 1.1892268631996628 1.170768208808996 1.0925681339726059 1.2096273588397455 1.0 14.66765425338473 -6.79419923386125 24.99868453697441 1.1406192918440234 0.9910386275417695 0.13626506356660406 0.17937213033950283 453.1360979007173 345780.11779671797 0.07198783974596505 0.06349164878454948 1.6062042330904475e-07 6.79419923386125 -0.14958066430225392 DYNPYNYSDSIS(ph)PFNK ddPTM_PC-9_AZD4547_30min_R2 1 DYNPYNYSDSISPFNK 16 0 E3W994;J3KR49;O75122;A0A0U1RQI6;H7C4X8;H7C5M8;E7ERI8;E7EW49;O75122-3 E3W994;E7ERI8 CLASP2 CLIP-associating protein 2 1 DYNPYNYS(0.016)DS(0.003)IS(0.98)PFNK 171.29 2.4555e-05 4490900.0 14929.0 17031.0 14656.0 19297.0 17187.0 17264.0 13689.0 15498.0 13301.0 16992.0 True False 19676.111457509553 22535.937690642913 14461.651863939715 14848.374785678025 14800.881719214938 16184.479350855469 14907.29448089314 13103.140208610821 14004.063705470318 16397.115251962266 1.199973968296337 1.3743842953074326 0.8819631771636823 0.905547991675005 0.9026515635086296 0.987032115232504 0.909141288075606 0.7991125272503496 0.8540565514287296 1.0 14.001154403065918 -5.267653988222747 24.998394177862597 0.9007857437367474 1.287179141038958 0.8371082653112105 0.06742605646497951 157.45166869201864 633354.9128310324 0.0176620467282596 0.038313558305986775 5.399406335368774e-06 5.267653988222747 0.38639339730221056 DYNPYNYSDSIS(ph)PFNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DYNPYNYSDSISPFNK 16 0 E3W994;J3KR49;O75122;A0A0U1RQI6;H7C4X8;H7C5M8;E7ERI8;E7EW49;O75122-3 E3W994;E7ERI8 CLASP2 CLIP-associating protein 2 1 DYNPYNYSDS(0.024)IS(0.976)PFNK 231.21 7.125799999999998e-93 0.0 10785.0 10167.0 13027.0 14645.0 18858.0 17959.0 22280.0 20810.0 16584.0 14909.0 True False 12610.687486540326 11176.312568637803 13337.613085172625 13824.488129730622 15162.910273285703 17017.19842498737 20169.477106768663 20263.759550017574 16826.509626154413 17611.883680420946 0.7160328625472113 0.6345892791162628 0.7573075843102457 0.7849522731687835 0.860947673084069 0.9662338642348244 1.1452197546132434 1.1505730969904546 0.9554065840702985 1.0 14.10426160053387 -6.52999114560143 1.2579048835424387 1.0757610315048975 0.6958682774623881 0.8466962420581339 0.06548243123177386 0.15975621026910128 0.5272980664768607 0.029844493802158374 0.033364413329839304 2.9512693965516303e-07 6.52999114560143 -0.37989275404250944 DYNPYNYSDSIS(ph)PFNK ddPTM_PC-9_Lapatinib_30min_R1 2 DYNPYNYSDSISPFNK 16 0 E3W994;J3KR49;O75122;A0A0U1RQI6;H7C4X8;H7C5M8;E7ERI8;E7EW49;O75122-3 E3W994;E7ERI8 CLASP2 CLIP-associating protein 2 1 DYNPY(0.001)NY(0.019)S(0.103)DS(0.255)IS(0.622)PFNK;DYNPYNYSDSIS(1)PFNK 176.46 6.140399999999999e-29 2953500.0 24016.0 30926.0 28818.0 28132.0 32706.0 43561.0 45478.0 47046.0 48940.0 35744.0 True False 23673.527436005003 30854.39274708778 26448.69528069694 30200.921125600922 30782.297382470017 41697.99757565068 47832.62831443701 49231.928909866896 43427.86183895303 41922.30277411381 0.5647000729793626 0.7359899315010853 0.6308979595707821 0.720402247184031 0.7342701937995038 0.9946495019686364 1.1409828456268083 1.1743612743588752 1.035913081229137 1.0 15.355430345221308 -6.791985010323501 2.3640584695444624 1.1028635992596951 0.6677446286491631 0.9046587850697222 0.06440484551269599 0.07897409985337332 0.9050624500925893 0.024247498015181446 0.021977606405396595 1.6144142773827983e-07 6.791985010323501 -0.43511897061053206 DYNS(ph)LTR ddPTM_PC-9_AZD4547_30min_R2 1 DYNSLTR 7 0 P16144-4;P16144-2;P16144-3;P16144;J3QRK0 P16144-4 ITGB4 Integrin beta-4 1 DYNS(1)LTR 76.17 0.031649000000000004 7428500.0 18292.0 32731.0 29723.0 28106.0 47400.0 33723.0 35048.0 34755.0 29094.0 23146.0 True False 24108.475502764075 43310.65566040945 29328.853599336795 21626.595933371333 40819.328183556645 31614.295478967742 38167.204103027456 29384.41334044841 30631.849443421794 22335.665585094102 1.079371259876539 1.9390805926693846 1.3130951252650227 0.9682539278258189 1.8275402641592993 1.415417658297401 1.7088008395191352 1.3155826151005032 1.3714321306755335 1.0 14.447061625997526 -8.786564129974828 1.484940227604535 1.0018054868870683 1.4648766157479975 0.1719671033486736 0.29251022752197525 1.6444620456813788 6.239292404240985 0.27193783035074226 0.07920494314988853 1.634691747001099e-09 8.786564129974828 0.46307112886092927 DYNSLT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 DYNSLTR 7 0 P16144-4;P16144-2;P16144-3;P16144;J3QRK0 P16144-4 ITGB4 Integrin beta-4 1 DYNS(0.002)LT(0.998)R 126.24 0.011151000000000001 86078000.0 53850.0 122140.0 132500.0 123530.0 150650.0 107400.0 128450.0 122420.0 138490.0 86227.0 True False 70973.17985041786 161619.36642211984 130742.96342603787 95052.06701947491 129734.84790828741 100684.261021888 139881.80115937808 103502.80193174213 145810.29866706146 83208.21897545627 0.8529587668659588 1.942348585417894 1.5712746293079871 1.1423398816829884 1.5591590531045376 1.2100278345290216 1.681105579253399 1.2439011819526158 1.7523545205320497 1.0 16.34443841860687 -11.207227786364042 3.030673114409284 0.9506043669065564 1.4475460835950753 0.1522637893967671 0.3105841299071172 5738431626.730068 4597974882.5571785 2145407817.2826173 0.0719496945629478 6.205434753671976e-12 11.207227786364042 0.49694171668851894 DYNSLT(ph)R ddPTM_PC-9_Lapatinib_30min_R1 2 DYNSLTR 7 0 P16144-4;P16144-2;P16144-3;P16144;J3QRK0 P16144-4 ITGB4 Integrin beta-4 1 DYNS(0.111)LT(0.889)R;DYNS(0.009)LT(0.991)R 120.27 0.014981 155469000.0 1052350.0 1009170.0 365440.0 221671.0 437040.0 254690.0 167354.0 182573.0 465220.0 97764.0 True False 1037343.2960226429 1006833.3288682213 335394.9338391932 237973.42481277828 411334.1664536996 243797.50241138786 176018.77125058888 191056.0080955051 412822.0246162187 114662.37713765861 9.0469369458236 8.780851696973468 2.925065241204033 2.0754272739965773 3.5873507659785377 2.126220548512572 1.5351048499480215 1.6662484492723506 3.6003267586246075 1.0 16.80703256831179 -5.275656337360397 4.23392388387751 2.2942679322457673 9.062832286896798 0.9195670235464983 0.7829496102288755 0.047301484767943006 2.108422117630096 0.20589491459997844 0.5129011482158705 5.300827390550921e-06 5.275656337360397 6.768564354651031 DYNVTANSK ddPTM_PC-9_AZD4547_30min_R2 3 DYNVTANSK 9 0 P00338-3;P00338;P00338-2;P00338-5;F5GYU2;F5GXY2;F5GXH2 P00338-3 LDHA L-lactate dehydrogenase A chain 0 ;; 130.98 0.005751600000000001 17604000.0 55374.0 51188.0 77693.0 93332.0 75128.0 68791.0 65881.0 75348.0 64294.0 63185.0 False True 72981.78014924869 67733.51996410261 76662.74005629557 71815.74936502568 64697.77400367604 64489.48789531383 71744.28137159179 63704.69792479081 67692.44958119754 60972.912382017224 1.1969541440302471 1.1108788692875247 1.2573245571078504 1.1778303931928686 1.0610904330487154 1.0576743897562904 1.1766582662492495 1.0448032648605985 1.1102052852105866 1.0 15.895880837775172 -6.234570141114857 9.255399456949258 1.0815239682667133 1.1856326289121568 0.4947317380552094 0.05456164154536252 0.3688640139295294 122.02894625562375 0.01578572595591823 0.020145791225174917 5.82679661002008e-07 6.234570141114857 0.10410866064544355 DYNVTANSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 DYNVTANSK 9 0 P00338-3;P00338;P00338-2;P00338-5;F5GYU2;F5GXY2;F5GXH2 P00338-3 LDHA L-lactate dehydrogenase A chain 0 ;; 117.02 0.0086767 18725300.0 52619.0 60716.8 60622.0 69954.0 76825.0 65145.0 69299.0 64108.0 59001.0 57645.0 False True 61526.35742737738 66744.36264064806 62067.4583902153 66034.70417392794 61771.69274287696 61728.68151878177 62734.49703868765 62425.232928040736 59863.77800607431 68095.5821824312 0.9035293547024157 0.9801570160871353 0.911475552465852 0.9697355108444176 0.9071321628088552 0.9065005326396621 0.9212711754283713 0.9167295575915727 0.8791139760828609 1.0 16.05527358351012 -6.293561557423719 24.810896046081286 0.9168371732114913 0.9418803645142245 0.054278552770421595 0.03632638921108173 1384.3065539109978 1069224.0163930017 0.010421244827663769 0.011817604047183366 5.086727146505421e-07 6.293561557423719 0.025043191302733248 DYNVTANSK ddPTM_PC-9_Lapatinib_30min_R1 2 DYNVTANSK 9 0 P00338-3;P00338;P00338-2;P00338-5;F5GYU2;F5GXY2;F5GXH2 P00338-3 LDHA L-lactate dehydrogenase A chain 0 ; 139.43 0.0038320999999999997 44600000.0 161878.0 157674.0 190393.0 175464.0 161006.0 141072.0 166900.0 149563.0 145904.0 156453.0 False True 159569.59003521057 157308.91554046187 174739.62247823348 188368.20789074522 151535.94362997529 135038.679414894 175541.2653520282 156512.24298657538 129470.75508276679 183495.69258948189 0.8696094594013223 0.8572894181902935 0.9522818765515245 1.026553840215553 0.8258283422978914 0.7359228846695801 0.9566506051166584 0.85294777647302 0.7055792605029692 1.0 17.485386671822845 DYPDFS(ph)PSVDAEAIQK ddPTM_PC-9_AZD4547_30min_R2 1 DYPDFSPSVDAEAIQK 16 0 P12429;D6RFG5;D6RCA8;D6RAZ8 P12429 ANXA3 Annexin A3;Annexin 1 DYPDFS(0.816)PS(0.184)VDAEAIQK 115.56 0.0018465 0.0 5517.7 3638.9 6552.7 8090.1 8061.4 7610.0 5419.0 7162.0 6214.0 7306.6 True False 7272.213824710326 4815.103262432069 6465.806916541879 6225.052435799026 6942.213759892898 7134.145496988539 5901.280502005985 6055.277466387325 6542.459353867568 7050.798157955958 1.0314029223066792 0.6829160549715662 0.9170319120887062 0.8828862061204831 0.9845997012493493 1.0118209792941717 0.8369663078990732 0.8588073762336664 0.9279033674343957 1.0 12.783570866052527 -5.479407608272544 24.975170180623813 0.9231180100115559 0.8428631233723514 0.07445004945860467 0.09585867048068304 1008.9892882639535 579685.7633598502 0.02422127404550118 0.05041499053813904 3.315831032367697e-06 5.479407608272544 -0.08025488663920455 DYPFHEEF ddPTM_PC-9_AZD4547_30min_R2 2 DYPFHEEF 8 0 P15121 P15121 AKR1B1 Aldose reductase 0 ; 97.602 0.026552 42719000.0 132517.0 123021.0 173015.0 136899.0 147349.0 160157.0 191141.0 251120.0 162624.0 145198.0 False True 174654.64947516905 162785.132443226 170720.70805400735 105339.05061846595 126892.13477887976 150142.35747190463 208152.17871081812 212315.17416352782 171219.9726365241 140114.66221483168 1.2465122972453713 1.1617994139231103 1.2184357108340935 0.751806049083958 0.9056306654354389 1.0715677795497085 1.4855845592495345 1.5152959069907634 1.2219989680594598 1.0 17.096248408062863 -7.19200609769659 7.9306719145887685 1.3482619244929415 1.0493375818013675 0.26974668447293715 0.19330323140530303 0.3750431879034411 39.135985420072 0.07729509088129193 0.05975233317453745 6.426786937457936e-08 7.19200609769659 -0.298924342691574 DYPFHEEF ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DYPFHEEF 8 0 P15121 P15121 AKR1B1 Aldose reductase 0 ; 115.46 0.016738999999999997 26002100.0 307011.0 391906.0 374461.0 380116.0 427550.0 295096.0 365651.0 246667.0 271968.0 249426.0 False True 358981.8985563496 430811.83766347746 383389.5703912503 358819.3328726994 343774.6466933555 279620.64627318166 331013.89019600826 240192.25261529014 275945.01748709334 294644.95934487076 1.2183541145741268 1.4621388352319598 1.301191682503916 1.217802380432767 1.1667419916421524 0.9490087558087029 1.1234330664675278 0.8151921320810861 0.936533983478435 1.0 18.168618059851305 -6.465039761244648 0.9932834948406345 0.9352271564248761 1.3523576446006131 0.7476498551809093 0.09283476478428411 0.24834175725529195 0.5270580035271232 0.045225659117729904 0.05636821758425289 3.4273640634127026e-07 6.465039761244648 0.41713048817573706 DYPFHEEF ddPTM_PC-9_Lapatinib_30min_R1 3 DYPFHEEF 8 0 P15121 P15121 AKR1B1 Aldose reductase 0 ;; 114.19 0.016994 69750000.0 192434.0 247609.0 290355.0 267072.0 254292.0 280096.0 266612.0 273640.0 298920.0 246384.0 False True 189689.85587192673 247035.67657355138 266483.1327027126 286713.36580607505 239335.0445173075 268116.9470156667 280415.8648174649 286354.31337193394 265252.4818328534 288971.1461139571 0.6564318217332386 0.8548800802282582 0.9221790351263089 0.9921868313212431 0.8282316339740184 0.9278329363372962 0.970393994654683 0.9909443113016162 0.9179203024244152 1.0 18.140565920669722 -4.665392774266813 1.6889494309644475 0.9426938392684107 0.49118672973371014 0.768280447770476 0.04800521950959742 0.6367079995959365 1.4347693634312255 0.013581285939054806 0.5136428762943543 2.160763453585985e-05 4.665392774266813 -0.4515071095347005 DYQDDTLELYNREDR ddPTM_PC-9_Lapatinib_30min_R1 1 DYQDDTLELYNREDR 15 1 H0YIQ2;P49750-3;P49750-1;P49750 H0YIQ2 YLPM1 YLP motif-containing protein 1 0 67.102 0.039557 1143300.0 9390.7 6092.4 9645.2 8467.0 8157.3 8818.5 8521.2 8385.3 10948.0 8376.8 False True 9256.786895956537 6078.293422115941 8852.208887548697 9089.691425084 7677.503651868848 8441.353311927534 8962.386041448184 8774.911650042652 9714.920952449078 9824.718718615617 0.9421935793863515 0.6186735311412989 0.9010139772017866 0.925185919863649 0.7814476802599668 0.8591954185856824 0.9122282579415217 0.8931463486497767 0.988824334893324 1.0 13.262200388311463 -7.828545724496747 0.6105633748829213 1.008682575448378 0.8181437459064458 0.31318702553342603 0.08778192304447059 0.9000762538889586 0.7090669857471287 0.08356275306461487 0.04521958626866992 1.484069622244626e-08 7.828545724496747 -0.19053882954193213 DYQYS(ph)DQGIDY ddPTM_PC-9_AZD4547_30min_R2 2 DYQYSDQGIDY 11 0 Q15417-3;Q15417;Q15417-2 Q15417-3 CNN3 Calponin-3 1 DYQY(0.003)S(0.997)DQGIDY;DYQY(0.026)S(0.971)DQGIDY(0.003) 80.905 0.015648 2263520.0 16128.1 19097.0 23872.0 22954.0 20863.0 27335.0 21007.0 27016.0 25042.0 23739.0 True False 21256.50031468014 25269.73178781091 23555.441682312277 17662.30993576481 17966.532571593714 25625.738128801797 22876.582304048658 22841.297965920126 26365.668995743737 22907.904835589234 0.927911149764185 1.1031009587813718 1.028266960744356 0.7710137641363439 0.7842940111957027 1.1186417227030818 0.9986326758485606 0.9970924067413782 1.1509419645738441 1.0 14.483557894869085 -6.788094852028109 24.999895007196994 1.0494781910036863 0.9303410761641264 0.2781419883527825 0.1044090555720813 371.25216080742416 348190.8933635188 0.040676098697782465 0.035882691822875 1.6289402253145394e-07 6.788094852028109 -0.11913711483955991 DYQYS(ph)DQGIDY ddPTM_PC-9_Lapatinib_30min_R1 1 DYQYSDQGIDY 11 0 Q15417-3;Q15417;Q15417-2 Q15417-3 CNN3 Calponin-3 1 DYQYS(0.999)DQGIDY 92.295 0.0077247 1460500.0 11492.0 13923.0 16455.0 11622.0 13027.0 14735.0 15283.0 14834.0 14683.0 14322.0 True False 11328.121972625311 13890.762148926566 15102.133418136864 12476.720649855477 12260.777472067422 14104.818398962665 16074.278959706686 15523.241794179432 13029.245921155436 16797.53861713457 0.6743917802974954 0.8269522377973338 0.8990682362671705 0.7427707674461554 0.7299151233717445 0.839695548285559 0.9569425215257363 0.9241378840078823 0.7756639956680776 1.0 14.035962226540926 -7.012445635029414 6.47206475288681 0.9069840869369695 0.7826172415105106 0.41482939343082204 0.07765754844381761 0.1780374915052642 33.707295903695716 0.029344694204895345 0.024055342973879054 9.717495875487979e-08 7.012445635029414 -0.12436684542645893 DYS(ph)PSRNPPEVEAR ddPTM_PC-9_AZD4547_30min_R2 1 DYSPSRNPPEVEAR 14 1 Q9HCM7;A0A3B3IRR3 Q9HCM7 FBRSL1 Fibrosin-1-like protein 1 DYS(0.994)PS(0.006)RNPPEVEAR 128.85 0.00011785 4043300.0 5911.0 4577.8 10829.0 15671.0 11675.0 9623.6 7473.4 10944.0 11082.0 11208.0 True False 7790.575043562125 6057.4843262418635 10685.40038445709 12058.293064536472 10054.12777516928 9021.834770672664 8138.518122105838 9252.856268101486 11667.771895648606 10815.611331449687 0.7203083399371659 0.5600686027453559 0.9879608333729626 1.114897040491212 0.9295940346833506 0.8341493138200083 0.7524787894735655 0.8555093174618791 1.0787898656935833 1.0 13.400827592692583 -5.264528000101305 24.940067829574367 0.9338130790385721 0.6401884608911947 0.5445811653891323 0.1108715642934495 198.92439707649015 1606295.0833484265 0.031580722674738666 0.07058168574295366 5.438410677338338e-06 5.264528000101305 -0.2936246181473774 DYS(ph)PSRNPPEVEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DYSPSRNPPEVEAR 14 1 Q9HCM7;A0A3B3IRR3 Q9HCM7 FBRSL1 Fibrosin-1-like protein 1 DYS(0.959)PS(0.041)RNPPEVEAR 132.65 6.0835e-05 4496900.0 10859.0 7723.7 12558.0 12913.0 14551.0 12483.0 15032.0 14213.0 14337.0 10653.0 True False 12697.2142249737 8490.457891844966 12857.430346480205 12189.526474510852 11699.836005227497 11828.36950493442 13608.06013774446 13839.9238099183 14546.651502060779 12584.304570898408 1.0089722601228517 0.6746863002250765 1.0217036844621044 0.9686293275752009 0.9297165321541667 0.9399303265663078 1.0813517792006972 1.0997766091837566 1.1559360646515469 1.0 13.619337872580926 -7.240329163125101 3.121352029835678 1.0965682320641885 0.9162068636264079 0.3957944719379437 0.09689218256328327 0.257561290895557 5.135512223372183 0.042115001707367296 0.029398951432438168 5.750039616263343e-08 7.240329163125101 -0.1803613684377806 DYS(ph)PSRNPPEVEAR ddPTM_PC-9_Lapatinib_30min_R1 2 DYSPSRNPPEVEAR 14 1 Q9HCM7;A0A3B3IRR3 Q9HCM7 FBRSL1 Fibrosin-1-like protein 1 DYS(0.947)PS(0.053)RNPPEVEAR;DYS(0.5)PS(0.5)RNPPEVEAR 101.3 0.013179 0.0 27591.0 23045.0 27625.0 20584.9 20456.0 19821.0 19920.6 20449.0 22162.0 18076.8 True False 27197.547280430284 22991.64071838059 25353.779135583773 22098.78221521338 19252.81829804338 18973.302035007742 20951.9911957556 21399.135192744707 19665.88218379398 21201.35079417805 1.2828214364482289 1.0844422575515404 1.1958567820379629 1.0423289737407564 0.9080939457560533 0.8949100564015885 0.9882385041951701 1.0093288583584479 0.9275768499238399 1.0 14.371868565186015 -5.930673219062466 3.4403765834236553 0.9544037865148935 1.1776593796585701 0.7638892628448424 0.05771984004222154 0.11486238718871457 2.745247412403293 0.01689989568504043 0.025910353811635308 1.1730777052146635e-06 5.930673219062466 0.2232555931436766 DYS(ph)YER ddPTM_PC-9_AZD4547_30min_R2 1 DYSYER 6 0 P48634;P48634-2;P48634-3 P48634 PRRC2A Protein PRRC2A 1 DYS(0.897)Y(0.103)ER 101.6 0.035441 134630000.0 292820.0 257140.0 318280.0 426570.0 342890.0 428720.0 250470.0 326420.0 310820.0 295570.0 True False 385930.66896563413 340255.47635323333 314059.3992395424 328230.87694080296 295285.6422122311 401912.0706266659 272761.34477531596 275979.2893853882 327249.3106483936 285222.18426450656 1.3530878390852428 1.192948848739236 1.1011043900718924 1.1507901385272732 1.035282872451436 1.409119250885284 0.9563118152210952 0.9675940533764836 1.14734872917498 1.0 18.121726671799593 -1.5228787452803376 0.2779454332628413 1.0383100813799124 2.994706391845406 0.29931149870355966 0.12291064635768334 73.00883175210281 1.0273305155021717 0.14117347137781547 69.19186873305543 0.029999999999999995 1.5228787452803376 1.9563963104654938 DYSEADGLS(ph)ER ddPTM_PC-9_AZD4547_30min_R2 1 DYSEADGLSER 11 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;Q4VXN2;Q4VXN7;Q4VXN6;Q4VXN5;Q4VXN1;Q4VXN0 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 DYSEADGLS(1)ER 105.36 0.0025681999999999996 10132000.0 45228.0 55866.0 56669.0 55000.0 50157.0 52935.0 39741.0 73895.0 58685.0 50960.0 True False 59609.5631991588 73923.59198082658 55917.532033133204 42320.59974152933 43193.566322840736 49624.966081877596 43277.8720114818 62476.2256881724 61786.96929219801 49175.90591101684 1.2121701084067782 1.5032481987132145 1.137092057527425 0.8605962403236233 0.8783481569408997 1.0091317112016873 0.8800625267543123 1.2704641537508699 1.2564480134641693 1.0 15.585664009405429 -5.478623238897105 6.465419099425688 1.0190921630161864 1.3519749661800875 0.43739791707406916 0.15060660348056107 0.20416236835594692 22.319134581187367 0.04272987004071544 0.08780964036221375 3.321825090534698e-06 5.478623238897105 0.33288280316390106 DYSEADGLS(ph)ER ddPTM_PC-9_Lapatinib_30min_R1 1 DYSEADGLSER 11 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;Q4VXN2;Q4VXN7;Q4VXN6;Q4VXN5;Q4VXN1;Q4VXN0 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 DYSEADGLS(1)ER 156.36 0.00074682 12519000.0 56326.0 73047.0 59980.0 56952.0 59787.0 53409.0 50795.0 49245.0 60211.0 55924.0 True False 55522.78091107664 72877.86415949438 55048.675929495526 61140.44006630257 56270.446205764536 51124.8215724599 53424.916558156176 51533.102477711065 53429.40313006134 65590.38888595407 0.8465078779700089 1.1111058403116265 0.8392796088648284 0.9321554743730992 0.8579068848578612 0.7794559910500558 0.8145235523919406 0.7856806973246453 0.814591955278116 1.0 16.00119680838025 -5.959714240106477 1.3342367858023827 0.8251037524660032 0.9647048114133153 0.1779276765113874 0.0912706750730299 0.57744660882559 2.086495388997887 0.03088974101692319 0.05942436394323919 1.0971999013720959e-06 5.959714240106477 0.13960105894731212 DYSSGFGGK ddPTM_PC-9_Lapatinib_30min_R1 1 DYSSGFGGK 9 0 Q14247-3;Q14247;Q14247-2 Q14247-3 CTTN Src substrate cortactin 0 85.161 0.039322 0.0 21855.0 23586.0 25556.0 24706.0 25249.0 30317.0 21675.0 21583.0 20920.0 20967.0 False True 21543.343692283845 23531.38806611951 23454.884329012817 26522.96165679996 23763.903461443933 29020.41258237875 22797.22544341048 22585.82497261524 18563.76930263378 24591.118013228635 0.8760619863112665 0.9569059874976384 0.953794956227505 1.0785585934942892 0.9663612467176276 1.1801176573902579 0.9270511991828455 0.9184545802458163 0.7548973288911679 1.0 14.585849706816683 -7.511204748271782 23.923362201501675 0.8865560706609316 1.0040912841984222 0.22206409555542084 0.0950383912935954 467.93718221537773 958946.9946570996 0.04196491384447394 0.026493161727483824 3.081734722897624e-08 7.511204748271782 0.11753521353749063 DYSTVS(ph)ASPTALSTLK ddPTM_PC-9_Lapatinib_30min_R1 1 DYSTVSASPTALSTLK 16 0 A0A2R8YF49;A0A2R8YFR7;Q12774 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 DYS(0.008)T(0.043)VS(0.792)AS(0.15)PT(0.009)ALSTLK 165.89 5.2175e-05 4762900.0 15750.0 24292.0 21709.0 21376.0 24488.0 24515.0 28263.0 25375.0 23870.0 21962.0 True False 15525.402111803733 24235.75336649604 19924.16981916336 22948.06234824561 23047.663985260377 23466.550597256184 29726.319848078925 26554.015135991845 21181.50923775661 25758.10243747448 0.6027385809762297 0.9408982445553274 0.7735107765615702 0.8909065566436816 0.8947733646609468 0.9110356888369072 1.154057055260066 1.0308995082401498 0.8223241323452631 1.0 14.652738695638604 -3.674111184312282 0.42459174536784583 0.9969555768288606 8.733446637069606e-12 0.47566019641798696 0.10340802767782054 12.450279662544018 0.8467215448955905 0.07507016724206486 7.626169301219889 0.0002117818880190273 3.674111184312282 -0.9969555768201271 DYSTVSAS(ph)PTALSTLK ddPTM_PC-9_AZD4547_30min_R2 1 DYSTVSASPTALSTLK 16 0 A0A2R8YF49;A0A2R8YFR7;Q12774 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 DYSTVS(0.001)AS(0.785)PT(0.151)ALS(0.049)T(0.013)LK 91.65700000000001 0.003215 4311400.0 14306.0 14152.0 13994.0 19702.0 16669.0 14353.0 14610.0 20042.0 14446.0 12334.0 True False 18855.01041671456 18726.357242556423 13808.430416482825 15160.00829286565 14354.797077884086 13455.504641035031 15910.261696679729 16944.96941934302 15209.586067906479 11902.190414177423 1.5841630624775762 1.5733538610044686 1.160158755319085 1.2737158258540078 1.2060634705343996 1.1305065851582548 1.3367507276415314 1.4236849545911174 1.277881258712633 1.0 13.538939483239783 -5.251852280084445 24.292801157218722 1.242750225098949 1.578758555144355 0.6143584141480037 0.1111388929304218 310.8584189602833 787679.3422892103 0.028762805064805094 0.0738626937750805 5.599480285283919e-06 5.251852280084445 0.336008330045406 DYSTVSAS(ph)PTALSTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DYSTVSASPTALSTLK 16 0 A0A2R8YF49;A0A2R8YFR7;Q12774 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 DYST(0.001)VS(0.014)AS(0.971)PT(0.014)ALSTLK 243.04 8.115299999999999e-47 4641400.0 26317.0 25680.0 24305.0 24931.0 31074.0 21563.0 27633.0 24415.0 18163.0 23697.0 True False 30771.948315556954 28229.34068679246 24884.52337722578 23534.19689739254 24985.27276657545 20432.198320507978 25015.402194404793 23774.13211983081 18428.599513979894 27993.0785146512 1.0992698891424655 1.0084400210579771 0.8889527232312644 0.840714853319011 0.8925518053864099 0.7299017973251509 0.8936281224414838 0.849286087180006 0.6583270040961953 1.0 14.772782534327172 -5.001282589815771 1.124080061361158 0.8264945754670803 1.1791099871369668 0.4984601418546756 0.08765083457860158 0.9271465255418726 1.264615507049209 0.02683227064311841 0.35442880533602317 9.970510844282788e-06 5.001282589815771 0.3526154116698865 DYSTVSASPT(ph)ALSTLK ddPTM_PC-9_AZD4547_30min_R2 1 DYSTVSASPTALSTLK 16 0 A0A2R8YF49;A0A2R8YFR7;Q12774 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 DYSTVS(0.026)AS(0.408)PT(0.566)ALSTLK 142.19 6.2873e-05 4284100.0 12973.0 11580.0 12718.0 17569.0 15527.0 14804.0 11910.0 18924.0 17178.0 16235.0 True False 17098.144144836984 15323.00854075774 12549.351010206428 13518.738488344163 13371.344065529192 13878.303539739598 12969.966927272797 15999.73063025883 18085.994010417944 15666.617591549408 1.0913743215421141 0.9780674386935307 0.8010249140807243 0.8629009043813124 0.8534927202628416 0.8858519370017413 0.8278728226741688 1.0212626009898336 1.154428765796489 1.0 13.935406116435216 -7.935615488389406 5.595615368646786 1.081032585550688 0.8961326306729098 0.42540064269957256 0.08583126657502668 0.17918322332622816 10.652347435036477 0.05115263042459549 0.023728088717272614 1.1598037579831515e-08 7.935615488389406 -0.1848999548777781 DYSVTANSK ddPTM_PC-9_Lapatinib_30min_R1 2 DYSVTANSK 9 0 A0A5F9ZHM4;P07195;A0A3B3IS95;A8MW50;C9J7H8;F5H793 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain;L-lactate dehydrogenase 0 ; 102.06 0.015196000000000001 4023500.0 39581.0 32122.0 31356.0 29139.0 33013.0 27708.0 32169.0 32015.0 29476.0 29740.0 False True 39016.56768173359 32047.62348256979 28778.03071766026 31281.979264854468 31071.240246055244 26522.993430502724 33834.55341587414 33502.53377650359 26156.10248395952 34880.51937394094 1.1185776009655026 0.9187828638386736 0.825045934928371 0.8968323816939802 0.8907906419899358 0.760395599221436 0.9700128903800604 0.9604941204382743 0.7498770933869928 1.0 15.090133901677774 -4.776513276672768 3.7747422719244264 0.8794538800886454 1.144350031990443 0.43895837106750435 0.07983550858293177 0.23134831148268967 5.830411217741809 0.01933458549747222 0.17272994481460266 1.6729644919734914e-05 4.776513276672768 0.2648961519017975 DYTGCSTSES(ph)LSPVKQAPR ddPTM_PC-9_Lapatinib_30min_R1 1 DYTGCSTSESLSPVKQAPR 19 1 O95297-4;O95297-2;O95297 O95297-4 MPZL1 Myelin protein zero-like protein 1 1 DYT(0.001)GCS(0.033)T(0.033)S(0.029)ES(0.815)LS(0.089)PVKQAPR 55.972 0.014025999999999999 7889200.0 24777.0 15136.0 6842.9 2065.6 5951.0 6914.0 1271.6 1862.3 8706.1 0.0 True False 24423.675436454665 15100.953521953059 6280.303176357874 2217.5111146396034 5600.973880116157 6618.304337321202 1337.4372260134141 1948.8292566603984 7725.52733870268 0.0 0.0 DYTGCSTSESLS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 2 DYTGCSTSESLSPVK 15 0 O95297-4;O95297-2;O95297 O95297-4 MPZL1 Myelin protein zero-like protein 1 1 DYTGCSTSESLS(1)PVK;DYTGCSTSES(0.005)LS(0.995)PVK 125.36 2.6649000000000002e-05 19102600.0 26794.5 43825.0 41452.0 34260.0 31225.0 26094.0 39959.0 41483.0 29528.0 22388.7 True False 35314.59363977759 57990.574205415156 40902.31939574433 26361.88631172354 26889.947732733268 24462.338054982796 43515.273589159835 35072.75553450787 31088.789797393256 21604.878427589923 1.6345657189479967 2.684142583804585 1.8931983131879666 1.2201821176674066 1.2446238854273852 1.1322599262462791 2.0141410994282585 1.6233720384984516 1.4389708278891382 1.0 14.399069492337471 -5.573188854812156 5.421337346467487 1.4223528042812577 2.191261680669962 0.44476729974314 0.3580189053205673 0.16362417205398733 10.60407679286599 0.09784445329008737 0.17527427038089322 2.6718442930926125e-06 5.573188854812156 0.7689088763887044 DYTGCSTSESLS(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 DYTGCSTSESLSPVK 15 0 O95297-4;O95297-2;O95297 O95297-4 MPZL1 Myelin protein zero-like protein 1 1 DYTGCST(0.001)S(0.001)ES(0.003)LS(0.995)PVK;DYTGCSTSES(0.001)LS(0.999)PVK 182.02 9.4374e-06 14739900.0 31376.0 35725.0 22414.0 22888.1 44259.0 20726.2 24200.0 17641.0 19775.7 20412.7 True False 36687.33709575237 39271.54190170018 22948.43476556835 21605.7539612214 35586.766665889874 19639.28158561018 21907.60080717245 17177.94244218452 20064.88220055125 24113.360923155706 1.5214526590742505 1.6286216602841246 0.9516895980904638 0.8960075714901157 1.4758111396954385 0.8144564189204694 0.9085253970604696 0.7123827531519589 0.8321064104043346 1.0 14.557545127513595 -3.8353809607196716 0.4358000947321827 0.8436807447328049 3.16303849636544 0.5363572871336122 0.21590558115821917 8.837927703056872 0.6943582202383703 0.15377083440490952 12.587476505353331 0.00014608951231054714 3.8353809607196716 2.3193577516326354 DYTGCSTSESLS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 2 DYTGCSTSESLSPVK 15 0 O95297-4;O95297-2;O95297 O95297-4 MPZL1 Myelin protein zero-like protein 1 1 DYTGCSTS(0.002)ES(0.381)LS(0.616)PVK;DYTGCSTS(0.001)ES(0.04)LS(0.959)PVK 160.04 6.6111e-05 23849000.0 82164.0 145446.0 64247.0 49878.0 70757.0 54153.0 56139.0 46190.0 80324.0 31308.8 True False 80992.32629296795 145109.22872317588 58964.85966059187 53546.1945081304 66595.2123736144 51837.00242680862 59045.6027297634 48336.15602488524 71277.06527078188 36720.48436364632 2.2056442799308833 3.9517242552180387 1.6057756503606397 1.4582104630717159 1.81357118588404 1.4116644517393082 1.6079745066821394 1.3163267550124846 1.9410709446236758 1.0 15.164297468378017 -5.3279860689731855 9.547805008965325 1.5366513970656261 3.0767754524291213 0.6458454420761695 0.4617745275302768 0.23698346108309934 32.90341345683594 0.10909045698228677 0.22765143784823363 4.699091818163471e-06 5.3279860689731855 1.5401240553634952 DYTGCSTSESLS(ph)PVKQAPR ddPTM_PC-9_AZD4547_30min_R2 1 DYTGCSTSESLSPVKQAPR 19 1 O95297-4;O95297-2;O95297 O95297-4 MPZL1 Myelin protein zero-like protein 1 1 DYTGCS(0.001)T(0.002)S(0.008)ES(0.022)LS(0.967)PVKQAPR 93.06200000000001 0.00039681 7162100.0 8943.5 6452.9 9227.0 12091.0 14748.0 10453.0 9370.6 13355.0 6924.4 7779.6 True False 11787.346963643686 8538.673731662837 9104.643951185299 9303.606754087836 12700.49476901041 9799.37225755864 10204.565246742442 11291.291617369829 7290.409647557223 7507.2385719259455 1.5701308611296336 1.1373920849663741 1.2127820188415228 1.2392848135770702 1.691766506063249 1.3053231442789568 1.3592967838938028 1.5040539219833402 0.9711173526335535 1.0 12.874066615676222 -8.273262766954604 24.52032199175505 0.9855585401786937 1.3668645240907171 0.48251432036211017 0.16206072281909617 586.0545338440024 1215392.343929654 0.15400738680171916 0.04109929693206449 5.330123023982927e-09 8.273262766954604 0.3813059839120234 DYTGCSTSESLS(ph)PVKQAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 DYTGCSTSESLSPVKQAPR 19 1 O95297-4;O95297-2;O95297 O95297-4 MPZL1 Myelin protein zero-like protein 1 1 DY(0.002)T(0.006)GCS(0.027)T(0.027)S(0.108)ES(0.113)LS(0.718)PVKQAPR 55.54600000000001 0.014476 5999400.0 21437.0 13096.0 12595.0 19751.0 31071.0 21051.0 18987.0 26787.0 18835.0 12125.0 True False 25065.86069995037 14396.084331551157 12895.312566803494 18644.41550360597 24982.860595039765 19947.048501832458 17188.413906024092 26083.869633172555 19110.426242680805 14323.166518552804 1.750022292031762 1.0050909003189974 0.90031157217227 1.3016964844649297 1.7442274767021284 1.3926423654989306 1.2000428734637647 1.8210965849895069 1.3342319394197548 1.0 13.806062853688012 -6.0037998000799195 24.91964915478559 1.4516558940965898 1.1811144330454537 0.0670151315535904 0.30661839121521656 312.03698256458506 2046418.245335952 0.08527795652940623 0.12337473063255845 9.912888012707323e-07 6.0037998000799195 -0.2705414610511361 DYTYEELLNR ddPTM_PC-9_AZD4547_30min_R2 3 DYTYEELLNR 10 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 0 ;; 139.98 0.00056281 17859700.0 34286.0 35338.2 48818.0 57001.0 57241.0 44871.0 38364.0 51611.0 40405.0 47650.0 False True 45188.23480689749 46760.58207383461 48170.64142288548 43860.30010667117 49294.07520158156 42065.20927665872 41778.321679084256 43635.705852794796 42540.72581155762 45981.78800353121 0.9827420108897726 1.0169370114586147 1.0476026164790757 0.9538624314326986 1.0720347629325762 0.9148232616232385 0.9085841045562616 0.9489780138485209 0.9251646718977232 1.0 15.488774945946432 -6.7804275447978695 24.99997231179245 0.9343882527729047 1.0132188211626865 0.4862428877145475 0.038417308022418065 194.54258925642685 256134.65701176916 0.01277107233621372 0.011281494140299443 1.6579539173054178e-07 6.7804275447978695 0.07883056838978175 DYTYEELLNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 DYTYEELLNR 10 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 0 ;;; 117.31 0.004457399999999999 14321300.0 46320.9 48883.9 54588.2 61815.6 61609.2 55239.3 66590.5 48702.1 60284.3 45742.7 False True 54162.11349052256 53736.77052955971 55889.78971490134 58352.27234087916 49537.31952534273 52342.45386477 60282.565766529544 47423.72147914035 61165.84384080923 54035.489410986025 1.0023433502854662 0.9944718020567132 1.0343163414290888 1.079887921381822 0.9167552670536419 0.9686680815761833 1.1156106185701247 0.8776402693134223 1.131956876999684 1.0 15.721619630897063 DYTYEELLNR ddPTM_PC-9_Lapatinib_30min_R1 4 DYTYEELLNR 10 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 0 ;;; 157.34 0.00053632 25139900.0 74249.0 79544.0 92517.0 65958.0 85513.0 73391.0 81296.0 69311.0 82545.0 60833.0 False True 73190.195644401 79359.8207551687 84910.60938594778 70808.77134943796 80483.29346502654 70252.23801277706 85505.10909561702 72531.44209224547 73247.91286261496 71347.90299512267 1.025821258536558 1.1122936684010702 1.1900925720515185 0.9924436231052008 1.128040069664393 0.9846433470872927 1.1984249782570644 1.0165882814692355 1.0266302131910194 1.0 16.12258340724634 EAAAAALK ddPTM_PC-9_Lapatinib_30min_R1 2 EAAAAALK 8 0 B4DLR8;P15559-3;P15559-2;P15559;H3BRK3;H3BNV2 B4DLR8 NQO1 NAD(P)H dehydrogenase [quinone] 1 0 ; 104.37 0.017781 16478400.0 114018.0 113534.0 121560.0 123728.0 113157.0 103475.0 113983.0 124619.0 100925.0 118477.0 False True 112392.08241165984 113271.11899850816 111565.80603516959 132827.36986450816 106501.32773522167 99049.61546200629 119884.48201689773 130409.253684026 89557.76371263443 138955.59158932095 0.8088345429367912 0.8151605682287153 0.8028882088091781 0.9558979839909965 0.7664414689405455 0.7128148952418153 0.8627539248021965 0.938495905004288 0.6445063684613693 1.0 17.08426436436121 -10.72412329315602 5.1210913843498105 1.0000148580859114 0.8169951339489229 0.28416191078140696 0.08920809474132149 1.4808337671470242e-05 2.3096510786999057e-06 0.08452103613377743 0.020497698823160056 1.8874554376744357e-11 10.72412329315602 -0.18301972413698853 EAAENSLVAYK ddPTM_PC-9_AZD4547_30min_R2 2 EAAENSLVAYK 11 0 P62258;P62258-2;K7EM20 P62258 YWHAE 14-3-3 protein epsilon 0 ; 160.36 0.000346 9173200.0 40294.0 37865.0 56940.0 62951.0 51709.0 50799.0 52488.0 54735.0 42678.0 43415.0 False True 53106.653832734264 50104.12075956754 56184.93839606493 48438.619533254765 44530.09791231075 47622.53049954285 57159.33031727069 46276.963435173166 44933.87195113618 41895.054064497526 1.2676115359817046 1.1959435756409846 1.3410876212158145 1.1561894503986891 1.0628962990179358 1.136710085783106 1.3643455437310994 1.1045925221609616 1.0725340485767219 1.0 15.354492315650782 -14.522878575873605 0.0656055130039369 0.27163814291882443 1.4664656175332955 0.37272500564628164 0.09123211205915611 417.1810820494472 1.9761868957733797 46.29950479517458 6.520376476037288 3.000001170220478e-15 14.522878575873605 1.1948274746144711 EAAENSLVAYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAAENSLVAYK 11 0 P62258;P62258-2;K7EM20 P62258 YWHAE 14-3-3 protein epsilon 0 149.31 2.9059999999999997e-07 0.0 16707.0 17639.0 24399.0 21053.0 22570.0 24126.0 17881.0 16201.0 14850.0 16201.0 False True 19535.16512170877 19390.083347910117 24980.76469372278 19873.468664746906 18147.570520100646 22860.790088604328 16187.182232770681 15775.740916378421 15067.153156560114 19138.113052954574 1.020746667534859 1.013165890192954 1.3052888037917725 1.0384236214802174 0.9482424139666682 1.1945164094991612 0.8458086848991456 0.8243101539178617 0.7872851996886925 1.0 14.22416097199908 -7.278796556603839 24.24883476970819 0.8497101429036713 1.0848305482221674 0.4999527989753816 0.10854935537271962 464.98520417688513 649604.0555640992 0.04562538270199641 0.03084887502235053 5.262637346577167e-08 7.278796556603839 0.2351204053184961 EAAENSLVAYK ddPTM_PC-9_Lapatinib_30min_R1 2 EAAENSLVAYK 11 0 P62258;P62258-2;K7EM20 P62258 YWHAE 14-3-3 protein epsilon 0 ; 149.96 0.0014897 33287000.0 102292.0 102572.0 101134.0 105113.0 94784.0 102765.0 91038.0 96800.0 87748.0 88316.0 False True 100833.29732194467 102334.5008360048 92819.15290852942 112843.3606666891 89208.99147251381 98369.98050691545 95751.50218764486 101297.68138577373 77864.89621259613 103581.30292632733 0.9734700614227918 0.9879630584372033 0.8960994917639475 1.0894182393800302 0.8612460835327018 0.9496885801569955 0.9244091306299608 0.9779533421955713 0.7517273292843003 1.0 16.66040408547456 -6.305371357181436 24.999584293067727 0.912356236868615 0.9803514114050662 0.18275340205172885 0.07812589459862941 858.2976583398114 488413.7755755153 0.02307356834238541 0.026163128344635293 4.950267215835856e-07 6.305371357181436 0.06799517453645121 EAAEPLSEPKEDQEAAELLS(ph)EPEEESER ddPTM_PC-9_AZD4547_30min_R2 1 EAAEPLSEPKEDQEAAELLSEPEEESER 28 1 A0A0A0MTR7;A0A0A0MTC1;Q63HN8;Q63HN8-4 A0A0A0MTR7 RNF213 E3 ubiquitin-protein ligase RNF213 1 EAAEPLSEPKEDQEAAELLS(0.98)EPEEES(0.02)ER 78.079 0.00015424 0.0 2240.9 2449.4 839.7 1130.4 2038.3 959.09 2178.5 2392.9 866.61 713.81 True False 2953.4595863844283 3241.1206493723657 828.5650293497662 869.8037445059043 1755.3172286190616 899.1179506841971 2372.382279686295 2023.1322883717169 912.4172353806208 688.8197291668541 4.287710501493208 4.705324937908773 1.2028764483153491 1.2627451097516547 2.548296969864909 1.3053022621342514 3.444126495267136 2.9370997994188546 1.3246096137289995 1.0 9.427982654756224 -5.2533664680100305 24.98691182070254 1.9847407332632379 4.496518055371887 0.6280977783353737 0.8025774623612052 398.9774385440658 1234889.950493235 0.211438944044177 0.5388518466955368 5.579991430780364e-06 5.2533664680100305 2.5117773221086486 EAAEPLSEPKEDQEAAELLS(ph)EPEEESER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAAEPLSEPKEDQEAAELLSEPEEESER 28 1 A0A0A0MTR7;A0A0A0MTC1;Q63HN8;Q63HN8-4 A0A0A0MTR7 RNF213 E3 ubiquitin-protein ligase RNF213 1 EAAEPLSEPKEDQEAAELLS(0.954)EPEEES(0.046)ER 129.71 4.7596e-11 2536500.0 8328.9 6684.8 6022.7 8917.6 8577.6 7434.6 8035.4 6810.7 8135.0 8283.2 True False 9738.818266726541 7348.42276569588 6166.304009216943 8417.975783249287 6896.880854816813 7044.716488134703 7274.228740741873 6631.926341533143 8253.95898509202 9784.878590224878 0.9952927036269666 0.7509978481528606 0.630187074101982 0.8603045715517481 0.7048509382330831 0.7199595194949475 0.7434153294460749 0.6777729820948885 0.8435422993738265 1.0 13.256338234812363 -8.559924104998634 6.721023275506549 0.9999925649191785 0.7554502501297581 0.3631411228220215 0.09707448452322302 0.3837719084597878 66.51994711717202 0.09164017305937196 0.023718929213348137 2.7547100598040092e-09 8.559924104998634 -0.24454231478942046 EAAEPLSEPKEDQEAAELLS(ph)EPEEESER ddPTM_PC-9_Lapatinib_30min_R1 2 EAAEPLSEPKEDQEAAELLSEPEEESER 28 1 A0A0A0MTR7;A0A0A0MTC1;Q63HN8;Q63HN8-4 A0A0A0MTR7 RNF213 E3 ubiquitin-protein ligase RNF213 1 EAAEPLSEPKEDQEAAELLS(0.999)EPEEES(0.001)ER;EAAEPLSEPKEDQEAAELLS(0.998)EPEEES(0.002)ER 95.867 7.0435e-10 6846500.0 17457.6 15188.599999999999 17884.9 14107.900000000001 17560.5 16532.7 18723.1 16735.5 13807.5 14749.5 True False 17208.651422668245 15153.431729884793 16414.47255971049 15145.442028574764 16527.62591527134 15825.634960606041 19692.49050516811 17513.092425946466 12252.35395057916 17298.931422526635 0.9947811805450117 0.87597501601469 0.9488720521971431 0.8755131550410332 0.9554131126127882 0.9148330942567892 1.1383645627685757 1.0123800134348733 0.7082723002545792 1.0 14.078395303016366 EAAEQDVEK ddPTM_PC-9_AZD4547_30min_R2 1 EAAEQDVEK 9 0 P26373;P26373-2;J3KS98 P26373 RPL13 60S ribosomal protein L13 0 116.3 0.00085959 0.0 18000.0 23305.0 27470.0 31140.0 29208.0 31184.0 25568.0 22806.0 20798.0 20291.0 False True 23723.625576741364 30837.885495885927 27105.729851420838 23961.15410820406 25152.97336677897 29234.059550340415 27843.502468220886 19281.856729744384 21897.33982004148 19580.61826609972 1.2115871549273043 1.5749188854407177 1.384314299122489 1.2237179532624076 1.2845852477665003 1.4930100343641282 1.4219930182912992 0.9847419763617686 1.1183170787795167 1.0 14.25713869890136 -7.760752842664275 24.99999944761264 1.0386470867404372 1.3747279519480762 0.6554963063569603 0.11166213839441287 11.340887423221815 413031.1638729465 0.057486213147346775 0.030632457408495295 1.7347909878126413e-08 7.760752842664275 0.336080865207639 EAAEQDVEK ddPTM_PC-9_Lapatinib_30min_R1 2 EAAEQDVEK 9 0 P26373;P26373-2;J3KS98 P26373 RPL13 60S ribosomal protein L13 0 ; 122.26 0.00032081 0.0 70534.0 65276.0 81417.0 68396.0 82753.0 79440.0 68150.0 64912.0 79100.0 86279.0 False True 69528.1722256486 65124.85743254545 74723.20853870866 73426.07000236734 77885.63123865769 76042.53638368475 71678.47353948909 67928.04849290646 70190.92504007326 101192.21019045876 0.6870901633118425 0.6435757980774488 0.7384284659665846 0.7256099047957207 0.7696801077085417 0.7514663059593363 0.7083398356907075 0.6712774468020393 0.6936396083054567 1.0 16.62673870960591 -11.11483512867315 3.0031644571742864 1.0171921714433025 0.7110500224533229 0.8529908667612451 0.03612714162177259 17407705.40664383 18239736.424175292 2363796.4882919854 0.010764276811334926 7.676528583058655e-12 11.11483512867315 -0.3061421489899796 EAAFS(ph)PGQQDWSR ddPTM_PC-9_AZD4547_30min_R2 4 EAAFSPGQQDWSR 13 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 EAAFS(0.995)PGQQDWS(0.005)R;EAAFS(0.988)PGQQDWS(0.012)R;EAAFS(0.983)PGQQDWS(0.017)R;EAAFS(1)PGQQDWSR 160.87 0.00029604 81279200.0 66852.6 76881.0 79918.0 124378.0 110450.0 90573.0 77018.0 118648.0 87389.0 89957.0 True False 88110.33617953688 101731.27976010322 78858.23510250646 95704.57372094419 95115.92400577688 84909.45599195048 83872.45279636409 100313.67785980513 92008.20413182052 86807.63281077964 1.015006783696047 1.171916298902582 0.9084251297855223 1.1024903066940877 1.0957092242465287 0.9781335263113701 0.9661875353655414 1.1555859157968922 1.0599091479936666 1.0 16.405534280907254 -7.758521427444257 24.99997831438679 1.080810631302328 1.0373185074952778 0.040314207271800906 0.08000361549804619 246.74235787995678 2114052.9558895906 0.03882039937626923 0.021164902354133146 1.7437273224290017e-08 7.758521427444257 -0.043492123807050254 EAAFS(ph)PGQQDWSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 EAAFSPGQQDWSR 13 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 EAAFS(1)PGQQDWSR;EAAFS(0.962)PGQQDWS(0.038)R;EAAFS(1)PGQQDWSR;EAAFS(1)PGQQDWSR;EAAFS(0.842)PGQQDWS(0.158)R 201.72 1.9235e-07 53499500.0 135779.0 121695.0 146775.0 140039.0 174307.0 152761.9 159740.0 145154.0 138829.0 117732.0 True False 158763.70294250874 133776.0753457634 150274.6726472869 132193.06884256378 140152.79462326886 144750.79704204443 144608.27078255083 141343.86130337603 140859.1114863357 139075.8796340006 1.1415617385294967 0.9618927142349599 1.0805228990300666 0.9505103918123691 1.0077433627750716 1.0408044689199756 1.0397796595866196 1.0163075126710972 1.0128220066414675 1.0 17.085512704886128 -4.746091242513456 24.994212636580674 1.0145880449510722 1.1415620828913906 0.5391789970813643 0.03580196788805375 663.1461788065188 1079864.1860890954 0.008467178012069834 0.20088471079969497 1.7943566042981046e-05 4.746091242513456 0.12697403794031836 EAAFS(ph)PGQQDWSR ddPTM_PC-9_Lapatinib_30min_R1 4 EAAFSPGQQDWSR 13 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 EAAFS(1)PGQQDWSR;EAAFS(1)PGQQDWSR;EAAFS(0.995)PGQQDWS(0.005)R;EAAFS(1)PGQQDWSR 175.27 0.00016784 61404500.0 91368.0 78254.0 102265.0 84618.0 84694.0 91720.0 91926.0 76483.0 94157.0 78700.0 True False 90065.07556516098 78072.80767091154 93857.16645431603 90841.08999737295 79712.46543481057 87797.3494097628 96685.47848262762 80036.67939491884 83552.04714283402 92303.19013884176 0.9757525761534978 0.8458300038544173 1.016835564546976 0.9841598092192748 0.863593829367194 0.9511843445248067 1.0474771060154482 0.8671063185847453 0.9051913267261474 1.0 16.494092890020205 EAAGPAPS(ph)PMR ddPTM_PC-9_AZD4547_30min_R2 1 EAAGPAPSPMR 11 0 Q12834 Q12834 CDC20 Cell division cycle protein 20 homolog 1 EAAGPAPS(1)PMR 90.434 0.007696 122190000.0 59569.0 53711.0 75680.0 97729.0 93193.0 77225.0 63477.0 77116.0 66624.0 74565.0 True False 78510.70288782824 71072.03037414845 74676.43375156645 75199.0889479985 80254.76057827429 72396.10854204197 69126.33002875696 65199.49414938914 70145.60862440824 71954.5020458196 1.0911159226400282 0.987735698996163 1.0378285114670598 1.0450922014596502 1.1153542627140858 1.0061373018180455 0.960694995634023 0.9061211223151963 0.9748605942646997 1.0 16.13479733581289 -7.095726333759865 3.6787068854530145 0.9530571073453685 1.0508763809832478 0.5620739793471381 0.038976584727581295 0.17867456443719523 4.44922756540065 0.015677652001935206 0.012083206911804948 8.021833918432734e-08 7.095726333759865 0.09781927363787923 EAAGPAPS(ph)PMR ddPTM_PC-9_Lapatinib_30min_R1 2 EAAGPAPSPMR 11 0 Q12834 Q12834 CDC20 Cell division cycle protein 20 homolog 1 EAAGPAPS(1)PMR;EAAGPAPS(1)PMR 80.318 0.014353999999999999 201106000.0 523540.0 420900.0 362550.0 379340.0 415258.0 293246.0 255286.0 242006.0 416606.0 282506.0 True False 516074.22359452274 419925.43191001896 332742.53848347167 407237.9290411439 390833.3408686395 280704.55216981383 268503.45995600865 253250.48224633824 369683.4452243333 331336.7856844174 1.5575518502375374 1.2673673737813647 1.0042426704784695 1.2290755105864362 1.1795651969681682 0.847188010199301 0.8103641719146315 0.764329507583101 1.115733179039285 1.0 18.337938857687845 -6.688502235525662 4.665615554208752 0.8864821250418589 1.2407640085590805 0.5402955328772208 0.1568557408404111 0.17242598673605683 7.045780567366553 0.05524660821285626 0.0543439849688906 2.0487915038005509e-07 6.688502235525662 0.3542818835172217 EAALILGVS(ph)PTANK ddPTM_PC-9_AZD4547_30min_R2 1 EAALILGVSPTANK 14 0 Q96DA6-2;Q96DA6 Q96DA6-2 DNAJC19 Mitochondrial import inner membrane translocase subunit TIM14 1 EAALILGVS(0.963)PT(0.037)ANK 156.72 0.00036606 4601500.0 23458.0 21758.0 29094.0 33211.0 32888.0 36270.0 34594.0 37237.0 29797.0 28757.0 True False 30917.15604328883 28790.847999119764 28708.194550318098 25554.717054835106 28322.06888820278 34002.031166330395 37672.79898254197 31482.87727113443 31372.00858821887 27750.22618294957 1.1141226683869374 1.0374995796181863 1.0345211012354605 0.9208831988020538 1.020606776373036 1.225288433404629 1.3575672765395 1.1345088527775062 1.1305136174888049 1.0 14.760211909992007 -6.754027251339032 24.854255292392427 1.1897319207907568 1.0208779561695034 0.3530382586206392 0.09546915379494389 158.80973422403295 532518.0296432197 0.03247157617204212 0.03184502291781012 1.7618654884787836e-07 6.754027251339032 -0.16885396462125346 EAALILGVS(ph)PTANK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAALILGVSPTANK 14 0 Q96DA6-2;Q96DA6 Q96DA6-2 DNAJC19 Mitochondrial import inner membrane translocase subunit TIM14 1 EAALILGVS(0.903)PT(0.097)ANK 160.04 0.00046965 7443100.0 43690.0 39754.0 39606.0 45550.0 54859.0 40636.0 40903.0 40816.0 38074.0 33985.0 True False 51085.85408316612 43700.514394966805 40550.357246591455 42997.981175092464 44109.772758626576 38504.97662441041 37028.37172792457 39744.62324812676 38630.760221068675 40146.21147488803 1.2724950177458458 1.0885339559948775 1.0100668470786147 1.0710345906982595 1.0987281523741739 0.9591185621212545 0.9223378836403104 0.9899968586821083 0.9622516995217024 1.0 15.292976229202957 -1.5228787452804255 0.5520955346883345 0.9795089055595001 13.390758201739024 0.7603732397025431 0.046999789773330046 72.78742751942922 0.6622487094447719 0.02563620712645215 1072.1325406079684 0.02999999999999392 1.5228787452804255 12.411249296179523 EAALILGVS(ph)PTANK ddPTM_PC-9_Lapatinib_30min_R1 2 EAALILGVSPTANK 14 0 Q96DA6-2;Q96DA6 Q96DA6-2 DNAJC19 Mitochondrial import inner membrane translocase subunit TIM14 1 EAALILGVS(0.614)PT(0.386)ANK;EAALILGVS(0.935)PT(0.065)ANK 178.22 7.6742e-05 8608000.0 109914.0 90607.0 74080.0 62630.0 77331.0 61053.0 49094.0 40782.0 74656.0 42219.0 True False 108346.60620424077 90397.20505837747 67989.42835706938 67236.01912755542 72782.5426185956 58441.905511494224 51635.84710121313 42676.88060201063 66247.4551174679 49516.49789671864 2.188091056646005 1.8255977077968575 1.373066174810697 1.3578508574616102 1.4698645039559382 1.1802511888743055 1.0428008703061962 0.8618719500524035 1.337886521289261 1.0 15.595621661676287 -1.5228787455568153 0.38175420311039987 1.0362353161432676 18.092326566354863 0.8541550566059183 0.14420161715511653 24.47716804224633 0.33338502844399226 0.11354756783797866 309.3050662433339 0.029999999980901592 1.5228787455568153 17.056091250211594 up EAALILGVSPT(ph)ANK ddPTM_PC-9_AZD4547_30min_R2 2 EAALILGVSPTANK 14 0 Q96DA6-2;Q96DA6 Q96DA6-2 DNAJC19 Mitochondrial import inner membrane translocase subunit TIM14 1 EAALILGVS(0.409)PT(0.591)ANK;EAALILGVS(0.389)PT(0.611)ANK 179.97 0.00012778 18069100.0 119143.0 98305.0 126818.0 173047.0 150927.0 142600.0 131208.0 162033.0 123317.0 124993.0 True False 157027.99567164993 130080.16879094909 125136.31045859079 133153.68769949873 129973.39123965526 133683.1994573672 142885.25781642387 136994.52299792456 129835.28486335475 120617.03311490812 1.3018724770161956 1.078456047472381 1.0374679862949148 1.1039376799514486 1.0775707865060289 1.108327704678421 1.1846192376519615 1.1357809047368468 1.076425787555765 1.0 16.880074128401418 -4.758566192829431 24.997914349006237 1.0954832007982918 1.3018727553588711 0.6343548920873349 0.04823108361811466 54.32002159056247 472519.86471358984 0.01238550087719062 0.08379790610468268 1.743547595065133e-05 4.758566192829431 0.2063895545605794 EAALILGVSPT(ph)ANK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAALILGVSPTANK 14 0 Q96DA6-2;Q96DA6 Q96DA6-2 DNAJC19 Mitochondrial import inner membrane translocase subunit TIM14 1 EAALILGVS(0.431)PT(0.569)ANK 92.65 0.009935 7172600.0 31527.0 32492.0 32206.0 33607.0 45026.0 36936.0 33269.0 28291.0 33039.0 30243.0 True False 36863.8984133664 35717.59102785282 32973.91318193515 31724.108745364058 36203.47852184546 34999.01113788813 30117.519473298333 27548.391226792282 33522.13287135284 35725.81649654372 1.031856008579476 0.9997697612119881 0.9229715767342981 0.8879883472623556 1.0133702199737817 0.979656018254309 0.8430183667380154 0.7711059936015022 0.9383167736585091 1.0 15.124679363356297 -7.25578773402561 24.58245482627633 0.8690357817800003 0.9695879901189741 0.24611462915943594 0.06917855161496946 447.10586702381374 1944741.6064231903 0.027110017451914093 0.020387603381255878 5.5489685833832585e-08 7.25578773402561 0.10055220833897383 EAALPPVS(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 6 EAALPPVSPLK 11 0 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 EAALPPVS(1)PLK;EAALPPVS(1)PLK;EAALPPVS(1)PLK;EAALPPVS(1)PLK;EAALPPVS(1)PLK;EAALPPVS(1)PLK 150.49 5.7041000000000005e-05 3772974000.0 1717383.0 1910113.0 1799157.0 1715099.0 1757142.0 2007180.0 1908576.0 1972499.0 1858103.0 1732994.0 True False 2263475.070214486 2527519.672954434 1775299.002631699 1319709.423565403 1513193.1637787144 1881670.7172990064 2078435.5665983711 1667694.603067789 1956318.5311875427 1672322.407542321 1.3534920419687106 1.51138300937373 1.061576998923739 0.7891477251117355 0.9048453557484373 1.125184180282765 1.2428438184075297 0.9972327079672795 1.169821394704977 1.0 20.673421581170444 -5.285676723089085 10.064797637116135 1.0331163599925104 1.4324184677838399 0.606570825911847 0.1275843748172218 0.32744565803332387 134.74030914341037 0.036411224952440036 0.07748189913611955 5.179922677278825e-06 5.285676723089085 0.39930210779132946 EAALPPVS(ph)PLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 EAALPPVSPLK 11 0 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 EAALPPVS(1)PLK;EAALPPVS(1)PLK;EAALPPVS(1)PLK;EAALPPVS(1)PLK;EAALPPVS(1)PLK;EAALPPVS(1)PLK;EAALPPVS(1)PLK;EAALPPVS(1)PLK 149.69 8.1716e-05 2702423000.0 1954998.0 2380297.0 2141597.0 2346867.0 2884043.0 2353058.0 3383345.0 2540706.0 2488744.0 2402927.0 True False 2285940.5484294244 2616597.1553251524 2192660.7945318534 2215379.6506354697 2318935.477425909 2229659.496158132 3062850.068303426 2474015.1596005326 2525137.1727589327 2838558.643540339 0.8053173583823965 0.9218048608154351 0.7724556966690314 0.7804593559047908 0.8169411904534973 0.7854900236893576 1.0790159559583181 0.8715744398061347 0.8895842890212416 1.0 21.43672711677486 -7.228013821075995 24.977078309746016 0.9493416036132126 0.8154121037695691 0.5341464951087203 0.06662307106350569 541.8193974232877 404872.33122105186 0.02561532390904346 0.019840147513648643 5.915428084971696e-08 7.228013821075995 -0.13392949984364355 EAALPPVS(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 6 EAALPPVSPLK 11 0 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 EAALPPVS(1)PLK;EAALPPVS(1)PLK;EAALPPVS(1)PLK;EAALPPVS(1)PLK;EAALPPVS(1)PLK;EAALPPVS(1)PLK 143.25 6.2859e-05 3297616100.0 1571316.0 2464135.0 2123023.0 2255058.0 3024050.0 3205020.0 3475270.0 3519100.0 2944937.0 2707728.0 True False 1548908.745695937 2458429.4468035 1948476.244045769 2420902.487972966 2846181.3245110526 3067948.7658665287 3655202.4759732964 3682610.2331061703 2613247.183498587 3175755.176979232 0.48772926733264554 0.7741243609156138 0.6135473723447263 0.7623076569383791 0.8962218955487403 0.9660532991037274 1.1509711146720425 1.1596014263949204 0.822874257575579 1.0 21.59866826688939 -6.30683960165945 1.3421370698086093 1.0451034842247013 0.6285973426072767 0.7132500989264705 0.1102764190353326 0.22906241176233116 0.8367599901398484 0.04327637864640657 0.058634169068208515 4.933559818841364e-07 6.30683960165945 -0.4165061416174246 EAALPPVS(ph)PLKAALSEEELEK ddPTM_PC-9_AZD4547_30min_R2 3 EAALPPVSPLKAALSEEELEK 21 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 EAALPPVS(1)PLKAALSEEELEK;EAALPPVS(0.987)PLKAALS(0.013)EEELEK;EAALPPVS(1)PLKAALSEEELEK 137.61 4.7217e-05 88742200.0 146106.0 84970.1 135274.0 275215.0 228937.0 155826.0 128401.0 145575.0 112720.0 184319.0 True False 192564.66880640952 112435.02314413124 133480.17837353866 211768.4337793634 197153.0492902727 146082.17558656208 139828.44025430345 123079.72873070875 118678.14907755902 177866.04791233715 1.0826387107972215 0.6321331387513924 0.7504533886046961 1.1906062807654856 1.1084355423888506 0.8213044439968665 0.7861446402813151 0.6919798925951831 0.667233294215041 1.0 17.440431621448674 -6.986292214369907 24.61285232689072 0.766821572582199 0.9397867304661315 0.1660295251277687 0.17678293636701928 372.7647901826926 669310.0593207414 0.06675022372125196 0.05883737236889497 1.0320667475741852e-07 6.986292214369907 0.17296515788393252 EAALPPVS(ph)PLKAALSEEELEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EAALPPVSPLKAALSEEELEK 21 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 EAALPPVS(1)PLKAALSEEELEK;EAALPPVS(0.999)PLKAALS(0.001)EEELEK;EAALPPVS(0.995)PLKAALS(0.005)EEELEK;EAALPPVS(1)PLKAALSEEELEK 95.414 0.00016473 72543500.0 61604.7 22951.699999999997 38846.8 87625.0 94201.0 134454.0 117553.0 158291.0 126184.0 100615.0 True False 72033.15896171275 25230.193093498987 39773.05503930939 82715.65533408309 75742.99027753652 127402.99554726052 106417.52882998131 154136.02897317774 128029.20228332565 118855.70303209845 0.6060555541222898 0.2122758306909788 0.33463312255675426 0.69593341525854 0.6372684553225114 1.0719131879843726 0.8953506320285022 1.29683326118185 1.0771818180971071 1.0 16.858851603958037 -6.481732973787218 1.081691448795045 1.1151490785103126 0.36838123941506096 0.7885472296183018 0.1511633107228259 0.20622251117689186 0.5124963009087483 0.07000315755791381 0.08405603407425254 3.298124352149735e-07 6.481732973787218 -0.7467678390952517 EAALPPVS(ph)PLKAALSEEELEK ddPTM_PC-9_Lapatinib_30min_R1 4 EAALPPVSPLKAALSEEELEK 21 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 EAALPPVS(0.999)PLKAALS(0.001)EEELEK;EAALPPVS(1)PLKAALSEEELEK;EAALPPVS(1)PLKAALSEEELEK;EAALPPVS(1)PLKAALSEEELEK 96.37899999999999 0.00015116 77010700.0 825762.0 330394.0 363445.0 374499.0 354758.0 409058.0 264937.0 259882.0 469228.0 298292.0 True False 813986.4824537951 329628.99299234635 333563.95503827144 402040.90575204114 333891.8319210635 391563.5429007715 278654.1415133032 271957.06646588474 416378.60145010723 349851.37475089374 2.326663666916792 0.9421972208257109 0.953444745717465 1.1491762924707905 0.9543819347824658 1.119228252796143 0.796492915632287 0.7773502867025393 1.1901585401703314 1.0 18.416382635211676 -4.760432744116561 24.99995443606266 0.9811675775623269 2.3266652537146797 0.9047811742867238 0.13037277400509278 6.918113288436545 171727.9031638794 0.032540491900174856 0.19300025446974614 1.7360700940269887e-05 4.760432744116561 1.3454976761523527 EAALPPVS(ph)PLKAALSEEELEKK ddPTM_PC-9_AZD4547_30min_R2 4 EAALPPVSPLKAALSEEELEKK 22 2 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 EAALPPVS(1)PLKAALSEEELEKK;EAALPPVS(1)PLKAALSEEELEKK;EAALPPVS(0.995)PLKAALS(0.005)EEELEKK;EAALPPVS(1)PLKAALSEEELEKK 101.54 0.00022084 89043400.0 219921.0 116921.1 175925.0 370487.0 305376.0 205031.0 168051.0 179385.0 149977.0 247737.0 True False 289851.3033590304 154713.55905827208 173592.11955264694 285076.94611709047 262979.8135734553 192210.37915808882 183007.2134420757 151665.170107217 157904.47803588613 239063.8030352738 1.2124432878542593 0.6471643013034647 0.72613301281346 1.192472229160629 1.1000402831149336 0.8040128899385418 0.7655161974273162 0.6344129398997257 0.6605118634902138 1.0 17.867036180668933 -6.953559894268281 8.066101271194901 0.7415834330831489 0.9557930688604741 0.20966906599968405 0.19393836732211397 0.4122789457184793 63.074287210293186 0.07161560653671739 0.06298784151179761 1.1128589060110606e-07 6.953559894268281 0.2142096357773252 EAALPPVS(ph)PLKAALSEEELEKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 EAALPPVSPLKAALSEEELEKK 22 2 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 EAALPPVS(1)PLKAALSEEELEKK;EAALPPVS(0.999)PLKAALS(0.001)EEELEKK;EAALPPVS(1)PLKAALSEEELEKK;EAALPPVS(0.979)PLKAALS(0.021)EEELEKK;EAALPPVS(0.999)PLKAALS(0.001)EEELEKK 98.26899999999999 0.00034989999999999994 239886300.0 162763.5 56325.7 92813.6 261072.0 248480.0 380237.0 298310.0 440150.0 365410.0 295661.0 True False 190316.14582434006 61917.34325241686 95026.6282215379 246444.98224684407 199792.12772860503 360296.70235101774 270051.91722262796 428596.5288774737 370753.4299621985 349261.9988488123 0.544909398822755 0.1772805041959904 0.2720783495907117 0.7056163655340144 0.5720408415090431 1.0315943433255734 0.7732072716549028 1.2271490465328396 1.0615338375896124 1.0 18.41395015451628 -6.472484834273225 0.9113536669234092 1.0740090983431272 0.30676393253162443 0.7625209725083095 0.16143148498157883 0.2600226512487107 0.4709884797078897 0.08463478393040527 0.10716631570773665 3.369109805943272e-07 6.472484834273225 -0.7672451658115027 EAALPPVS(ph)PLKAALSEEELEKK ddPTM_PC-9_Lapatinib_30min_R1 3 EAALPPVSPLKAALSEEELEKK 22 2 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 EAALPPVS(1)PLKAALSEEELEKK;EAALPPVS(1)PLKAALSEEELEKK;EAALPPVS(1)PLKAALSEEELEKK 78.55199999999999 0.0018058 36455600.0 328047.0 100683.0 118783.0 127312.0 106856.0 130829.0 84765.0 78767.0 152527.0 93228.0 True False 323368.9896235477 100449.87469944512 109017.12025563983 136674.94918038225 100570.94016697894 125233.74864729473 89153.71694166974 82426.8023730706 135347.80307948487 109342.33558149853 2.957399692477979 0.9186732125780742 0.9970257144761986 1.2499728348907575 0.9197804275181061 1.1453363235866816 0.8153632028028049 0.7538416107056138 1.2378353028558011 1.0 16.73849257176756 -4.7599979577370455 24.999996295477153 0.999837580897559 2.9574020778054253 0.9326502793285922 0.15745802989883917 8.375177928967455 145208.2660045365 0.039036598640600766 0.23834486140151984 1.7378090007495908e-05 4.7599979577370455 1.9575644969078663 EAALPPVSPLK ddPTM_PC-9_Lapatinib_30min_R1 1 EAALPPVSPLK 11 0 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 0 88.681 0.040050999999999996 0.0 44301.0 52734.0 42382.0 49699.0 58806.0 60970.0 68122.0 62671.0 63315.0 53678.0 False True 43669.259616191564 52611.89766296733 38897.515559251115 53354.030251003845 55347.14669704431 58362.45522801182 71649.02383649406 65582.92345173376 56183.79796349226 62956.170778560925 0.6936454215074764 0.8356908784687992 0.6178507218310244 0.8474789618108891 0.8791377558797177 0.9270331169488243 1.138077855600668 1.0417235140048788 0.8924271801903345 1.0 15.942060173146054 -6.453415180744177 1.441016863031686 1.017855699458832 0.7313768169762165 0.6861095604485756 0.0822385980484607 0.23306186799065928 0.9855023168580463 0.03334338133393634 0.03920801682639768 3.5203416933572e-07 6.453415180744177 -0.28647888248261544 EAALPPVSPLKAALSEEELEKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAALPPVSPLKAALSEEELEKK 22 2 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 0 57.496 0.043627 19353000.0 20882.0 8958.7 9209.4 34136.0 36751.0 41471.0 33963.0 61725.0 49501.0 30354.0 False True 24416.91016170006 9848.060530014307 9428.987022843989 32223.4705904052 29549.90536926094 39296.18775447694 30745.778769173463 60104.784153043525 50224.85847830859 35856.93991786823 0.6809535397506865 0.27464866083306855 0.2629612857215776 0.8986676125797227 0.8241056107115162 1.0959158211628333 0.857456850461805 1.6762385270666142 1.4007011918292709 1.0 15.129964751367226 -6.519260073741263 0.8366074944457091 1.3307390500358547 0.38692004429010973 0.640808055168518 0.25100153612748743 0.3772616946677724 0.5832598665404676 0.1498897292982267 0.1850111489420913 3.0251013280881003e-07 6.519260073741263 -0.943819005745745 EAALSTALSEKR ddPTM_PC-9_AZD4547_30min_R2 1 EAALSTALSEKR 12 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 60.08 0.038887 4350100.0 27832.0 23606.0 19856.0 39999.0 27364.0 23009.0 23017.0 17514.0 15979.0 23473.0 False True 36681.997058436995 31236.1778595101 19592.696466320074 30777.84852838967 23564.980937022032 21570.243592668772 25065.468410162724 14807.613731682159 16823.617318224948 22651.217414625153 1.6194271763403156 1.379006579988143 0.8649732201002895 1.3587723769989253 1.0403405921046385 0.9522774514866282 1.1065837191593406 0.6537226437163314 0.7427246408116893 1.0 14.467300971138526 -1.5228787452810946 0.34514210196918227 0.8412266532638926 9.520882931562703 0.6112672969627855 0.1789868774523458 42.057513811441595 0.59407783357686 0.15868131234556052 236.4342225992276 0.029999999999947707 1.5228787452810946 8.679656278298811 EAALYPHLPPEADPR ddPTM_PC-9_Lapatinib_30min_R1 1 EAALYPHLPPEADPR 15 0 Q13501;Q13501-2 Q13501 SQSTM1 Sequestosome-1 0 82.925 0.0061246 4192800.0 20953.0 21848.0 25544.0 22432.0 20425.0 20194.0 23364.0 21187.0 26511.0 20197.0 False True 20654.206377690392 21797.412298337113 23443.870922691465 24081.724110958352 19223.64165709503 19330.349694513192 24573.673599070014 22171.425366946176 23525.0520067937 23688.02453918915 0.8719260799278703 0.9201870026044495 0.9896929515547503 1.0166201943567674 0.8115341836670127 0.8160389087124306 1.037388050591372 0.9359761228829389 0.9931200454421248 1.0 14.531870269712684 -7.283336810160502 24.993906366985254 0.9862857243392879 0.909819635701637 0.29420414769469827 0.06569753945512208 1359.389687342177 1551611.9626821384 0.030174733429035955 0.020363165298796105 5.207906635540372e-08 7.283336810160502 -0.07646608863765081 EAAPGKSELCS(ph)SPLGK ddPTM_PC-9_AZD4547_30min_R2 2 EAAPGKSELCSSPLGK 16 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 EAAPGKSELCS(0.5)S(0.5)PLGK;EAAPGKSELCS(0.5)S(0.5)PLGK 177.04 9.572499999999999e-29 0.0 85945.0 41453.1 84010.0 188915.0 143608.0 97586.0 71697.0 102776.0 69710.0 109713.0 True False 113273.72223294672 54852.003915447734 82895.97250884103 145363.5654576547 123670.50805451919 91483.93199331457 78077.89410450695 86894.33075752924 73394.72828421442 105871.98126403823 1.0699121796015982 0.5180974537413274 0.78298310392533 1.3730126112887875 1.1681136649940698 0.8640995559076131 0.7374745723307612 0.8207490756295578 0.6932403399646642 1.0 16.69196130890583 -6.991286063743686 24.738565183931552 0.7983367695860427 0.9721331819750547 0.11245240895114295 0.22505986537474112 432.6955306124737 1228400.1194996934 0.08733003393572701 0.07689880480260122 1.0202672264762706e-07 6.991286063743686 0.173796412389012 EAAPGKSELCS(ph)SPLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAAPGKSELCSSPLGK 16 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 EAAPGKS(0.001)ELCS(0.499)S(0.499)PLGK 69.258 0.01029 10403000.0 40439.0 22628.0 33688.0 52674.0 55655.0 72021.0 51701.0 95840.0 70653.0 55382.0 True False 47284.52399334298 24874.358296757782 34491.249682451446 49722.846551412134 44749.80227276041 68244.09197427558 46803.50699717447 93324.30155087369 71686.16646265592 65422.3181963292 0.7227583078215666 0.380212120000258 0.527209225129334 0.7600288085511779 0.6840143166200321 1.0431316690655683 0.7154058169678338 1.4264902883877026 1.0957448228527948 1.0 15.997495260815036 -6.7912006002097565 0.8451883247814983 1.154950051435262 0.5300103516436399 0.6003250672524084 0.1838029913519404 0.38730109479803854 0.6003563327737619 0.11747627185084901 0.10731621064140101 1.6173328205892978e-07 6.7912006002097565 -0.6249396997916221 EAAPGKSELCSS(ph)PLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAAPGKSELCSSPLGK 16 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 EAAPGKS(0.001)ELCS(0.138)S(0.861)PLGK 77.192 0.0051088999999999996 8535100.0 49548.0 23648.0 32688.0 67196.0 64598.0 85526.0 60038.0 97465.0 86391.0 57132.0 True False 57935.49778239218 25995.617155812608 33467.40588993035 63431.225972371365 51940.48562062306 81040.86600008182 54350.76600252143 94906.64702270375 87654.30493928512 67489.57934333677 0.8584361963149818 0.38517971824311203 0.49588997613502805 0.9398669630118819 0.7696074879410422 1.2007908004257397 0.8053208588843793 1.4062414960373266 1.2987828016139387 1.0 16.04237714111629 -6.48335557543109 0.8946243087971919 1.1988438669969028 0.5626770147149455 0.5444678126639073 0.21029796945324536 0.42363945441624357 0.7418008721505505 0.11422874825825187 0.14368730793909348 3.285824961991333e-07 6.48335557543109 -0.6361668522819574 EAARAGPEGTSPPTPTPST(ph)ATGGPPEDSPTVAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPK 34 1 A0A669KBI7;Q9UMN6;Q9UMN6-2 A0A669KBI7 KMT2B Histone-lysine N-methyltransferase 2B 1 EAARAGPEGT(0.002)S(0.002)PPT(0.118)PT(0.118)PS(0.133)T(0.612)AT(0.009)GGPPEDS(0.003)PT(0.003)VAPK 41.733999999999995 0.029341000000000002 12643000.0 6717.0 5986.5 9607.3 11011.0 9230.4 9094.1 8932.6 7914.9 7476.1 4640.4 True False 7854.055433202724 6580.800156599803 9836.37446788814 10394.089368143654 7421.769380980815 8617.189386751912 8086.4394615763895 7707.1422615297515 7585.423819108357 5481.667786613809 1.432785739475542 1.20051057684854 1.7944127318164904 1.8961545596626526 1.3539254237742608 1.57200139121802 1.4751786821746866 1.4059849231196635 1.3837802862902244 1.0 12.420399181755398 -8.858038960017595 0.7198581400448245 0.9961023824450489 1.5481077481970764 0.41616776541391953 0.18929753570223232 1.3042692239745979 1.2887664036671023 0.21166412693896905 0.07535172788201441 1.3866314303118733e-09 8.858038960017595 0.5520053657520275 EAARS(ph)PDKPGGSPSASR ddPTM_PC-9_AZD4547_30min_R2 1 EAARSPDKPGGSPSASR 17 2 Q9Y3T9 Q9Y3T9 NOC2L Nucleolar complex protein 2 homolog 1 EAARS(1)PDKPGGSPSASR 79.804 0.017301 106170000.0 8672.2 7831.6 8826.6 10182.0 7666.5 8622.2 7490.7 6352.7 8342.1 5935.8 True False 11429.779207034253 10363.011544714882 8709.553516802016 7834.697210331844 6602.138808422726 8083.052470976949 8157.357788591297 5371.036185523422 8783.046375265312 5727.989448716904 1.995426023278478 1.8091883090036496 1.5205254120628655 1.3677918369920972 1.152610155366406 1.4111500280063523 1.424122348971607 0.9376826255723217 1.5333558928312543 1.0 12.483813119740196 -5.239183124689135 1.1390473193087656 1.2501764312468107 2.10244664206636 0.6867178916677286 0.1759908099068035 0.47357668399460034 0.8509695796711448 0.05548627548517383 0.400561133073111 5.765233152084029e-06 5.239183124689135 0.8522702108195495 EAAS(ph)SPAGEPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAASSPAGEPLR 12 0 Q96EB6;Q96EB6-2 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 EAAS(0.646)S(0.354)PAGEPLR 84.169 0.010355 4702200.0 31760.0 35734.0 37654.0 31534.0 42454.0 34565.0 35584.0 25331.0 28601.0 25227.0 True False 37136.34071140666 39281.43536222125 38551.814163590214 29767.252214607375 34135.44345858897 32752.350551795123 32213.225914149738 24666.088090413035 29019.23551722398 29800.45540317789 1.2461668860082749 1.3181488279549016 1.293665269272331 0.9988858160682009 1.1454671748052816 1.0990553704190187 1.0809642160943136 0.827708427831028 0.9737849682031838 1.0 14.863046757313604 -6.159628715014602 0.5346765897075009 0.9373488692130437 1.3469181181033267 0.6567787356352045 0.08672994500446478 0.7764594851230904 0.42598350590990325 0.06959059995382376 0.16784085550994718 6.924226806768691e-07 6.159628715014602 0.409569248890283 EAAS(ph)SPAGEPLR ddPTM_PC-9_Lapatinib_30min_R1 1 EAASSPAGEPLR 12 0 Q96EB6;Q96EB6-2 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 EAAS(0.5)S(0.5)PAGEPLR 91.20200000000001 0.023005 0.0 16285.0 15442.0 33233.0 16048.0 21388.0 21265.0 17177.0 15926.0 36836.0 14704.0 True False 16052.772913696757 15406.244997753645 30500.7110230898 17228.223454558658 20129.99989042587 20355.545521136144 18066.341012293513 16665.98010072143 32687.14177972361 17245.566808151572 0.9308347526222792 0.8933452387584894 1.7686116880004683 0.9989943297436465 1.1672564963716294 1.1803349665210516 1.0475933446127141 0.9663921334753587 1.8953938796765537 1.0 14.073937926027028 -8.211373786216477 24.99829398841725 1.447704601831353 1.1305408392943037 0.15180372913793028 0.3096936213879123 593.6391197714065 296411.0518322636 0.20096227501585848 0.07595638163131574 6.146476334035347e-09 8.211373786216477 -0.31716376253704937 EAASGT(ph)TPQK ddPTM_PC-9_AZD4547_30min_R2 2 EAASGTTPQK 10 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 EAAS(0.029)GT(0.699)T(0.271)PQK;EAAS(0.002)GT(0.625)T(0.373)PQK 131.12 0.00046576 133815000.0 131779.0 94354.0 92130.0 106725.0 99505.0 94865.0 84125.0 88111.0 139410.0 165261.0 True False 173681.980826522 124852.085306965 90908.29600332734 82121.20013481297 85690.44833132513 88933.07655345829 91611.96202828083 74495.46953935399 146778.9279888443 159475.26269153386 1.0890841494487302 0.7828931158336514 0.5700463787864538 0.5149463230147265 0.5373275258186749 0.557660636844209 0.5744587623315718 0.4671286836720713 0.9203868080327448 1.0 17.282973129398478 -10.287837712442403 8.487371928868244 0.9999999519587365 0.648420400905168 0.20563043999373676 0.19212156728060356 0.0 0.0 0.19162385471398274 0.04647561137492728 5.15421211668067e-11 10.287837712442403 -0.35157955105356853 EAASGT(ph)TPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EAASGTTPQK 10 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 EAAS(0.003)GT(0.811)T(0.186)PQK;EAAS(0.276)GT(0.655)T(0.069)PQK;EAAS(0.024)GT(0.798)T(0.178)PQK;EAAS(0.029)GT(0.498)T(0.473)PQK 149.49 0.00028232 172944700.0 126776.0 199697.0 207159.0 153770.0 422765.0 416231.0 202890.0 294491.0 402598.0 398060.0 True False 148236.67285986437 219521.598408504 212098.45621488226 145154.76542906617 339927.2330939461 394403.11362720194 183670.79040360393 286760.9232890061 408485.2341094134 470225.1269587733 0.31524617541941974 0.46684361558532883 0.4510572575877636 0.3086920649431661 0.7229031661758667 0.8387538032644968 0.39060182000803023 0.6098375157951686 0.8687014170240781 1.0 18.84299210736704 -7.396496158942647 0.13547213460660495 1.2693877335055097 2.93604846749941e-17 0.6027234449694019 0.14835981994473665 5.822391876779409 0.5797575317334808 2.0274725473935375 2.7940452041182726 4.013320477727178e-08 7.396496158942647 -1.2693877335055097 EAASGT(ph)TPQK ddPTM_PC-9_Lapatinib_30min_R1 1 EAASGTTPQK 10 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 EAAS(0.193)GT(0.42)T(0.387)PQK 130.1 0.00054861 226960000.0 49495.0 83399.0 59390.0 80414.0 103660.0 59454.0 104320.0 104990.0 91845.0 77176.0 True False 48789.19222372864 83205.8947395194 54507.183452029654 86327.91381324042 97562.92260340131 56911.291014043185 109721.17915831985 109868.21868483858 81500.44892927333 90515.76876944404 0.5390131784440935 0.9192419825926256 0.6021843949739504 0.9537334211139425 1.0778555375462515 0.628744491570347 1.2121775095099132 1.2138019726119529 0.9004005604467222 1.0 16.465881525820024 -5.4770048810753 0.4925294765677792 1.0695047651111478 0.5123392946621559 0.360710117968603 0.18462294512620414 2.812164087471207 0.8565480287369299 0.13485405239486864 0.8450980694446886 3.3342266537442436e-06 5.4770048810753 -0.5571654704489919 EAASGTT(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 2 EAASGTTPQK 10 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 EAAS(0.061)GT(0.211)T(0.728)PQK;EAAS(0.01)GT(0.361)T(0.63)PQK 155.47 0.00028653 346590000.0 155978.0 99577.0 119279.0 134724.0 116828.0 118740.0 100341.0 112565.0 176458.0 204799.0 True False 205575.75945605402 131763.31791563326 117697.28252448604 103665.46326505077 100608.44879807065 111315.16902922743 109271.15461372615 95170.66573637095 185785.20963385334 197629.04934596413 1.0402102329409002 0.6667203953654198 0.5955464690742317 0.5245456758918917 0.5090772289348424 0.5632530713354901 0.5529103893144727 0.4815621289042773 0.9400703502278287 1.0 17.592435497609912 -8.347534773117182 5.891058511940851 0.987777043214221 0.6075390570923419 0.4651465549589848 0.15149275472591525 0.2155069716730184 11.389220588109554 0.14990309178122985 0.039081830454018855 4.492263545470077e-09 8.347534773117182 -0.3802379861218791 EAASGTT(ph)PQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EAASGTTPQK 10 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 EAAS(0.004)GT(0.05)T(0.946)PQK;EAAS(0.003)GT(0.046)T(0.952)PQK;EAAS(0.003)GT(0.05)T(0.947)PQK 111.5 0.0038802 250544800.0 60731.0 89514.0 99025.0 61012.0 186559.0 180908.0 84787.0 146303.0 176669.0 182141.0 True False 71011.55880807422 98400.35834258333 101386.13155440404 57593.69544357285 150004.1031749868 171420.86600966734 76755.36155527792 142462.701270842 179252.44990008877 215161.72147263697 0.3300380677475898 0.45733208337012365 0.4712089625444726 0.26767630900786077 0.6971690974970354 0.7967070761304894 0.35673334936130463 0.6621191738743343 0.8331056689509015 1.0 17.715061911282717 -8.205437866538977 0.12264981040289118 1.3963044137679403 4.129375712076255e-07 0.6095607272479987 0.1457572017696213 5.449120036904604 0.6223362098021757 3.3812097002363397 2.9575434041893547 6.231062873617126e-09 8.205437866538977 -1.396304000830369 EAASGTT(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 5 EAASGTTPQK 10 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 EAASGT(0.022)T(0.978)PQK;EAAS(0.003)GT(0.051)T(0.946)PQK;EAASGT(0.205)T(0.794)PQK;EAAS(0.086)GT(0.261)T(0.653)PQK;EAAS(0.014)GT(0.317)T(0.669)PQK 169.89 0.00034909 395748500.0 202123.6 374375.0 282297.0 362184.0 442056.0 225440.1 454679.0 431058.0 396028.0 323069.0 True False 199241.28039907137 373508.1576890322 259087.6303579321 388820.21957040625 416055.1351955348 215798.55244954073 478220.0538585663 451086.5283345963 351423.15628027957 378911.04618761776 0.5258260016532141 0.9857410108442436 0.6837690084908342 1.0261517141885643 1.098028519837675 0.5695229912687425 1.2620905583781152 1.1904813355883028 0.9274555593353497 1.0 18.531499673000255 -4.032034878834982 0.4482130410813284 1.0512353212626675 5.479717971151426e-16 0.29456519481368015 0.20183192520766333 13.233762624469762 1.23976900138402 0.137707371489924 8.486937402862203 9.288917831052493e-05 4.032034878834982 -1.051235321262667 EAASS(ph)PAGEPLR ddPTM_PC-9_AZD4547_30min_R2 2 EAASSPAGEPLR 12 0 Q96EB6;Q96EB6-2 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 EAAS(0.046)S(0.954)PAGEPLR;EAAS(0.025)S(0.975)PAGEPLR 129.54 0.00017243 69416000.0 89986.0 91853.0 118655.0 121732.0 115788.0 118233.0 100599.0 137980.0 116194.0 100872.0 True False 118599.67617492483 121542.68596668579 117081.55717220034 93668.56814065178 99712.83484636393 110839.87181937518 109552.11611391393 116658.36146497095 122335.7776252475 97340.50198304717 1.218400087926197 1.2486342631338976 1.2028041235352502 0.9622774305906611 1.0243714878697658 1.1386819418568344 1.1254525493714171 1.1984565426351323 1.2567818650303808 1.0 16.570752594134895 -1.5230826996790439 0.010440287240156946 5.400329636344835e-07 2.4331190448957565 0.11253237287904172 0.09591298054828083 37011.35086083039 29.972141186807157 2990.5417444250206 4071.5586781877682 0.029985914636916234 1.5230826996790439 2.433118504862793 EAASS(ph)PAGEPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EAASSPAGEPLR 12 0 Q96EB6;Q96EB6-2 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 EAAS(0.028)S(0.972)PAGEPLR;EAAS(0.002)S(0.998)PAGEPLR 168.83 0.00017741 32907000.0 82145.0 113309.0 103617.0 92586.0 103566.0 78642.0 86391.0 59011.0 81110.0 65080.0 True False 96050.52606229528 124557.56868690661 106087.6222496609 87398.70658786206 83272.9857547518 74517.87507867122 78207.41906332364 57462.023777322815 82296.08030495569 76878.48882700352 1.2493810365918327 1.6201875269321873 1.379938964310101 1.1368421507937254 1.08317667302407 0.9692942228138187 1.0172861128853685 0.7474395588943902 1.0704695365454329 1.0 16.23029235739869 -5.989697938460681 1.4693111819479954 0.9531350213856641 1.4565551030547124 0.7254684633009332 0.11999703531923554 0.19491038795712967 0.8522805724591109 0.040679912445519585 0.07242087438155709 1.0240049630432992e-06 5.989697938460681 0.5034200816690483 EAASS(ph)PAGEPLR ddPTM_PC-9_Lapatinib_30min_R1 3 EAASSPAGEPLR 12 0 Q96EB6;Q96EB6-2 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 EAAS(0.22)S(0.78)PAGEPLR;EAAS(0.184)S(0.816)PAGEPLR;EAAS(0.31)S(0.69)PAGEPLR 91.307 0.0095381 66353000.0 95583.0 108266.0 128620.0 93002.0 116847.0 112569.0 95110.0 106335.0 107089.0 93282.0 True False 94219.96889222467 108015.31672884306 118045.36008755761 99841.6773255771 109974.28919004083 107754.6862811555 100034.330423196 111275.7122950028 95027.50912283688 109405.66940954776 0.8611982304090922 0.9872917675271464 1.0789693141556325 0.9125822991113108 1.0051973520527946 0.9849095285710288 0.9143432050923138 1.0170927420447906 0.8685793856542493 1.0 16.73932797506373 -9.657782458554761 8.558052056129995 0.9999999971432023 0.9644375792311711 0.0277893401840843 0.06598365783107196 0.0 0.0 0.06124332464897539 0.014853688023042308 2.1989610734711807e-10 9.657782458554761 -0.035562417912031186 EAASS(ph)PAGEPLRK ddPTM_PC-9_AZD4547_30min_R2 1 EAASSPAGEPLRK 13 1 Q96EB6;Q96EB6-2 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 EAAS(0.006)S(0.994)PAGEPLRK 80.318 0.018935 2528800.0 13416.0 10892.0 23059.0 30346.0 23715.0 22060.0 14587.0 31999.0 19321.0 20349.0 True False 17682.008929864573 14412.62599533103 22753.222593517065 23350.198541026333 20422.581600697176 20680.584712689506 15885.214741236627 27054.289813868745 20342.26861539674 19636.58770375356 0.900462401952078 0.7339679486459878 1.1587157064548315 1.189116912433972 1.040027010232199 1.0531659076763313 0.8089600383166443 1.377749037766744 1.0359370437618491 1.0 14.261256630455607 -5.263031349554638 24.994516008607604 1.0878583554271721 0.8172151665323916 0.3550940850115968 0.1431298295492465 139.14038574878282 2184597.536265308 0.03687075550138723 0.08390830487363207 5.4571846697254035e-06 5.263031349554638 -0.27064318889478056 EAASS(ph)PAGEPLRK ddPTM_PC-9_Lapatinib_30min_R1 2 EAASSPAGEPLRK 13 1 Q96EB6;Q96EB6-2 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 EAAS(0.001)S(0.999)PAGEPLRK;EAAS(0.004)S(0.996)PAGEPLRK 101.38 0.0026988000000000003 0.0 25450.0 29966.0 45636.0 28776.0 36760.0 38611.0 34013.0 33765.0 51843.0 24412.0 True False 25087.07833304161 29896.615568105535 41883.98424005435 30892.28303392195 34597.84907294068 36959.69753663709 35774.02671311283 35333.84516519268 46003.895409007804 28631.581673054672 0.8762030201304313 1.0441831649224391 1.4628596044161815 1.0789583120723938 1.20838064302612 1.2908716660742514 1.2494603728713998 1.234086386448065 1.6067535469862744 1.0 14.805319749811384 -5.033051349558516 5.600800770196247 1.266513577319035 0.9104063804499644 0.3782595244578202 0.16350531870895219 0.15636316642225848 14.486191646711282 0.03975412793428982 0.12202357183699299 9.267202445318973e-06 5.033051349558516 -0.35610719686907066 EAASSSSGTQPAPPAPAS(ph)PWDSKK ddPTM_PC-9_AZD4547_30min_R2 2 EAASSSSGTQPAPPAPASPWDSKK 24 1 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 EAASSSSGTQPAPPAPAS(0.984)PWDS(0.016)KK;EAASSSSGTQPAPPAPAS(0.993)PWDS(0.007)KK 148.69 9.8596e-09 138074000.0 157398.0 151511.0 174845.0 206929.0 204880.0 200560.0 166627.0 163043.0 160138.0 185037.0 True False 207447.2899182192 200483.96779091054 172526.44105830655 159224.71607118056 176435.94848622513 188018.9514948784 181456.48020072887 137848.45070541583 168602.5677517937 178558.910950879 1.1617862632198026 1.1227889256451784 0.9662158003739618 0.8917209184535336 0.988110576765122 1.052979940870057 1.0162275253271844 0.772005440508861 0.9442405694229157 1.0 17.446040607598285 -5.237243583386075 3.678878411495835 0.9493045109689686 1.1523724117180176 0.5144355289767308 0.0736512645543858 0.1895576215725201 5.596045397987372 0.02094484908453436 0.05910704372931364 5.791038025204044e-06 5.237243583386075 0.203067900749049 EAASSSSGTQPAPPAPAS(ph)PWDSKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EAASSSSGTQPAPPAPASPWDSKK 24 1 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 EAASSSSGTQPAPPAPAS(0.958)PWDS(0.042)KK;EAASSSSGTQPAPPAPAS(0.998)PWDS(0.002)KK 162.81 2.6430999999999997e-09 98573000.0 173010.0 142761.0 141606.0 172048.0 177747.0 177350.0 180321.0 182188.0 167729.0 130444.0 True False 202297.17589674037 156933.36860541985 144982.42408374554 162408.70834714227 142918.7513175156 168049.45379316827 163239.6894690138 177405.75804414233 170181.7193129073 154092.46460586414 1.3128297766809927 1.0184363590187369 0.940879389881782 1.0539691785873457 0.9274869584510278 1.0905754166694859 1.0593619219898023 1.1512941823463507 1.1044129883196825 1.0 17.23343678767459 -9.833601391844788 13.428093224994926 1.000004072245742 1.0652865271405927 0.03804475533325147 0.10376384898946123 0.0 0.0 0.10142262122117739 0.02459859883070151 1.4668935810379748e-10 9.833601391844788 0.06528245489485074 EAASSSSGTQPAPPAPAS(ph)PWDSKK ddPTM_PC-9_Lapatinib_30min_R1 2 EAASSSSGTQPAPPAPASPWDSKK 24 1 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 EAASSSSGTQPAPPAPAS(0.982)PWDS(0.018)KK;EAASSSSGTQPAPPAPAS(0.987)PWDS(0.013)KK 121.41 3.5073000000000005e-09 187801000.0 172437.0 142485.0 155996.0 135637.0 175592.0 151946.0 144165.0 146149.0 157842.0 122607.0 True False 169978.01675892703 142155.08473675206 143170.6110419738 145612.1974517682 165264.02378715464 145447.62378342595 151629.15829523728 152939.61608315547 140064.17181005346 143799.45658644158 1.1820490897109117 0.9885648257043236 0.9956269268368914 1.0126060341837033 1.149267373537049 1.011461567631124 1.0544487572808667 1.0635618500492698 0.9740243470659937 1.0 17.133698698325794 -7.572819889675733 0.008048930258248228 1.8314404995253006e-07 2.0722209671219898 0.11839501488992998 0.06292533296966418 5228.583441918259 34.43687116533499 4400.453073051522 4460.980036034457 2.6741151860374705e-08 7.572819889675733 2.0722207839779396 EAAST(ph)ASSPSSCARAVISQTTMALGAS(ph)PS(ph)MGR ddPTM_PC-9_AZD4547_30min_R2 1 EAASTASSPSSCARAVISQTTMALGASPSMGR 32 1 E9PK21 E9PK21 PPIE 3 EAAS(0.328)T(0.35)AS(0.137)S(0.146)PS(0.021)S(0.022)CARAVIS(0.444)QT(0.418)T(0.407)MALGAS(0.373)PS(0.355)MGR 45.761 0.008417200000000001 2251300.0 3726.5 3475.4 4521.2 4885.1 3932.2 2599.5 3473.8 4457.3 3901.2 4115.7 True False 4911.449483984816 4598.755084848829 4461.245933900396 3758.915669042635 3386.28190471269 2436.9528540633005 3782.9614703577017 3768.526703564397 4107.4094675423485 3971.610595721581 1.2366392337848218 1.1579068425798944 1.1232838231185795 0.9464461780547992 0.8526218326541286 0.6135930991544107 0.9525005987326397 0.9488661118046275 1.0341923933748836 1.0 11.955508462623678 -5.729455301617151 2.40184836096024 0.8861290590500233 1.1926790201489839 0.5555012959681016 0.11041526521097621 0.2249470993208356 2.6412525672355422 0.03526701924890643 0.06711958780607277 1.8644240583140363e-06 5.729455301617151 0.3065499610989606 EAATQEDPEQLPELEAHGVS(ph)ESEGEERPVAEEEILLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAATQEDPEQLPELEAHGVSESEGEERPVAEEEILLR 37 1 Q9BVJ6-3;Q9BVJ6;Q9BVJ6-2;X6RJY0 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 1 EAATQEDPEQLPELEAHGVS(0.5)ES(0.5)EGEERPVAEEEILLR 47.156000000000006 0.0025509 4267100.0 9446.2 7439.6 13091.0 11819.0 15187.0 11142.0 12237.0 14651.0 10125.0 6767.7 True False 11045.255089045631 8178.1543213964615 13403.139087893966 11156.819747714993 12211.216370791699 10557.693905630007 11077.822771792116 14266.42677401767 10273.058970381897 7994.630436916275 1.3815841990697517 1.022955893449776 1.6765176569017097 1.3955391479006816 1.5274272484697697 1.320598117566316 1.385657893658072 1.7845010956529692 1.2849948539140312 1.0 12.964815629293124 -5.254334009709267 24.91397163977425 1.4478368414252716 1.2022700734962346 0.12869087278179758 0.2204871595343448 882.2744921345006 3093550.727401264 0.05243130387952742 0.1325583278775481 5.567573900404949e-06 5.254334009709267 -0.24556676792903698 EAAVGVPPPAQPAPGEPTPPAPPS(ph)PDWTSSSR ddPTM_PC-9_AZD4547_30min_R2 4 EAAVGVPPPAQPAPGEPTPPAPPSPDWTSSSR 32 0 Q8IV56 Q8IV56 PRR15 Proline-rich protein 15 1 EAAVGVPPPAQPAPGEPTPPAPPS(0.865)PDWT(0.07)S(0.019)S(0.026)S(0.019)R;EAAVGVPPPAQPAPGEPT(0.005)PPAPPS(0.937)PDWT(0.026)S(0.012)S(0.015)S(0.005)R;EAAVGVPPPAQPAPGEPT(0.002)PPAPPS(0.737)PDWT(0.062)S(0.062)S(0.076)S(0.062)R;EAAVGVPPPAQPAPGEPTPPAPPS(0.711)PDWT(0.064)S(0.081)S(0.081)S(0.064)R 137.38 2.5115e-18 33836500.0 219400.2 249781.8 326543.0 436518.0 375753.0 344658.2 276988.0 382247.0 293941.0 313376.0 True False 289164.89979234256 330518.8821006769 322212.8264605941 335885.5192358711 323586.1819189029 323106.6682694063 301639.395403144 323179.50931222516 309478.121167555 302404.8016242305 0.9562179510352488 1.0929683666576864 1.0655016875723327 1.1107149007946107 1.0700431348341897 1.0684574667266693 0.9974689349607696 1.0686983393663483 1.0233902355562257 1.0 18.20612152148412 -7.227510332942799 24.182400734098614 1.0281142286083829 1.0650426722543895 0.152565027162489 0.04259627207301955 823.052741058479 586618.1947363348 0.01600621092476858 0.012398002921971248 5.922289961119255e-08 7.227510332942799 0.03692844364600667 EAAVGVPPPAQPAPGEPTPPAPPS(ph)PDWTSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EAAVGVPPPAQPAPGEPTPPAPPSPDWTSSSR 32 0 Q8IV56 Q8IV56 PRR15 Proline-rich protein 15 1 EAAVGVPPPAQPAPGEPTPPAPPS(0.721)PDWT(0.149)S(0.061)S(0.035)S(0.035)R;EAAVGVPPPAQPAPGEPTPPAPPS(0.899)PDWT(0.062)S(0.026)S(0.011)S(0.003)R 109.87 4.2737e-16 18717400.0 147609.0 174258.0 190616.0 209758.0 245690.0 210102.0 210247.0 181064.0 168825.0 176593.0 True False 172596.28828935878 191557.18260899838 195161.00835520582 198005.9393046112 197548.80820042192 199083.88125656752 190330.88210353666 176311.26185316572 171293.7462394786 208607.91299058107 0.8273717224578712 0.9182642204835607 0.9355398151364355 0.9491775094531119 0.9469861683019738 0.9543448203978553 0.9123857258095974 0.8451801244046117 0.8211277500638854 1.0 17.670434358160975 -9.81812886537204 8.767971653650848 0.9999999970298873 0.9056768221621475 0.2639956049522373 0.04899253099361448 0.0 0.0 0.0517204834309164 0.012544059869559143 1.5200964145024283e-10 9.81812886537204 -0.09432317486773978 EAAVGVPPPAQPAPGEPTPPAPPS(ph)PDWTSSSR ddPTM_PC-9_Lapatinib_30min_R1 2 EAAVGVPPPAQPAPGEPTPPAPPSPDWTSSSR 32 0 Q8IV56 Q8IV56 PRR15 Proline-rich protein 15 1 EAAVGVPPPAQPAPGEPTPPAPPS(0.924)PDWT(0.048)S(0.018)S(0.007)S(0.002)R;EAAVGVPPPAQPAPGEPT(0.435)PPAPPS(0.52)PDWT(0.028)S(0.011)S(0.004)S(0.002)R 117.86 8.499299999999999e-18 22911000.0 208921.0 210015.0 240490.0 195508.0 229230.0 247160.0 233300.0 266800.0 244470.0 184973.0 True False 205941.7482285807 209528.7231707836 220717.840518246 209886.31051556856 215747.14208351998 236589.54295810065 245379.13245433287 279196.5020012858 216935.21421677255 216945.33658897085 0.9492794427693194 0.9658134462127714 1.017389191160272 0.9674617293720562 0.9944769750560668 1.0905491064154476 1.1310643331284567 1.2869440126766 0.9999533413699624 1.0 17.726972049057586 -6.814455336835747 2.881727001591088 1.127078686020426 0.9772151252249947 0.3732236491290326 0.07781628620199019 0.2439725139518239 4.130611101192098 0.02838700288052814 0.02556476035857847 1.533008854015669e-07 6.814455336835747 -0.1498635607954314 EAAVSASDILQESAIHS(ph)PGTVEK ddPTM_PC-9_AZD4547_30min_R2 2 EAAVSASDILQESAIHSPGTVEK 23 0 F5H3K2;F5H8B7;E7ENF1;G5EA44;F5H7W8;Q96C57 F5H3K2 C12orf43 Uncharacterized protein C12orf43 1 EAAVSASDILQES(0.018)AIHS(0.778)PGT(0.203)VEK;EAAVSASDILQES(0.012)AIHS(0.986)PGT(0.002)VEK 88.765 1.3907000000000001e-05 110547000.0 114154.0 119148.0 213017.0 290100.0 251249.0 229443.0 183991.0 269168.0 187665.0 233229.0 True False 150452.59744929604 157660.26093386888 210192.2553971648 223221.92700032116 216367.41322342635 215095.89293896704 200365.84256220405 227574.27046530848 197584.588774309 225063.72369938297 0.6684888838427608 0.7005138737705028 0.9339232993315175 0.9918165545793515 0.9613606745102455 0.9557110733059321 0.8902627187926215 1.0111548263960959 0.8779050907298691 1.0 17.779974012985583 -5.25627331160917 4.139194083006671 0.9543299594910516 0.6759135676376659 0.8734777029351608 0.040986206674528625 0.05902305922568159 2.4908145667505406 0.010147070299889717 0.026542019897145618 5.5427678391499295e-06 5.25627331160917 -0.27841639185338574 EAAVSASDILQESAIHS(ph)PGTVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 EAAVSASDILQESAIHSPGTVEK 23 0 F5H3K2;F5H8B7;E7ENF1;G5EA44;F5H7W8;Q96C57 F5H3K2 C12orf43 Uncharacterized protein C12orf43 1 EAAVSASDILQESAIHS(0.979)PGT(0.021)VEK;EAAVSASDILQESAIHS(0.983)PGT(0.017)VEK;EAAVSASDILQES(0.006)AIHS(0.993)PGT(0.001)VEK;EAAVSASDILQESAIHS(0.793)PGT(0.206)VEK;EAAVSASDILQESAIHS(0.996)PGT(0.004)VEK 154.17 1.9286e-08 112195100.0 169824.4 202539.1 266091.3 286764.4 347546.3 280890.3 287514.7 273271.8 258558.0 209040.0 True False 198572.31673520774 222645.8433137197 272435.9257488742 270697.9203707293 279447.0973969898 266159.9181888872 260279.22618983177 266098.70480540575 262338.9216063214 246937.297240271 0.8041406419946197 0.9016290605022876 1.1032595269875045 1.096221281256428 1.131652044952475 1.077844137614872 1.05402962249392 1.077596247222592 1.062370587749102 1.0 17.913785231046184 -5.099839901544655 3.164232583635554 1.080366964817222 0.8147536054901893 0.875446974169418 0.03433485001837357 0.07820748949667872 1.434576904347061 0.009074951962820533 0.03403759599684097 7.946211101158067e-06 5.099839901544655 -0.2656133593270328 EAAVSASDILQESAIHS(ph)PGTVEK ddPTM_PC-9_Lapatinib_30min_R1 3 EAAVSASDILQESAIHSPGTVEK 23 0 F5H3K2;F5H8B7;E7ENF1;G5EA44;F5H7W8;Q96C57 F5H3K2 C12orf43 Uncharacterized protein C12orf43 1 EAAVSASDILQES(0.107)AIHS(0.804)PGT(0.089)VEK;EAAVSASDILQESAIHS(0.996)PGT(0.004)VEK;EAAVSASDILQES(0.002)AIHS(0.996)PGT(0.001)VEK 118.32 1.2726e-08 119280800.0 294373.1 259328.7 387077.7 314443.5 349296.5 350546.4 310053.9 306943.4 361900.6 231045.2 True False 290175.28561258473 258728.24032825726 355253.6656691322 337568.7239427661 328751.56661334116 335554.3476355699 326106.9738366158 321205.1109159716 321139.54344573326 270981.0549716222 1.0708323710783862 0.9547835008441897 1.3109907838624928 1.2457281339395374 1.2131902233821064 1.2382944913647562 1.2034308961959224 1.185341576552682 1.1850996132529037 1.0 18.047832466776505 -5.2533565756242515 24.998847255538475 1.2082933035290953 1.0128079258482918 0.4565959508287918 0.08005020327199447 466.60245642327766 1443120.3085718043 0.019110125481909927 0.04873295305153149 5.5801185336077075e-06 5.2533565756242515 -0.19548537768080343 EAAYHPEVAPDVR ddPTM_PC-9_AZD4547_30min_R2 2 EAAYHPEVAPDVR 13 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 ; 88.101 0.005682 5480100.0 22667.6 29841.0 38792.0 57725.0 46624.0 42516.0 28890.0 44410.0 34299.0 40790.0 False True 29875.42528463014 39486.519677439675 38277.59273375747 44417.39309235962 40151.06238882163 39857.46779894412 31461.15403265416 37547.45494027659 36111.97511720368 39361.95451550972 0.7589924243436229 1.0031646081467034 0.972451525969703 1.128434643022056 1.0200474768853507 1.0125886351308888 0.799278247736849 0.9539021982630926 0.9174334852446044 1.0 15.26451423894165 EAAYHPEVAPDVR ddPTM_PC-9_Lapatinib_30min_R1 2 EAAYHPEVAPDVR 13 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 ; 119.25 0.00019369 4760500.0 56970.0 56286.0 56730.0 52201.0 60665.0 60732.0 53045.0 48019.0 59683.0 49335.0 False True 56157.5973529815 56155.67322520156 52065.87838413273 56040.03567743123 57096.80397197895 58134.633933206715 55791.41054882162 50250.138041978025 52960.87205014777 57862.48901524466 0.9705354593057001 0.9705022058488805 0.8998209249245269 0.9685037168495589 0.9867671602743536 1.0047033047245921 0.9642068894430486 0.8684406581393161 0.9152885220024757 1.0 15.820340763181914 -7.574593598181027 24.994987129332447 0.9183833217253647 0.9665418454208706 0.1551550337033505 0.03939245298301959 153.02489532785756 73958.68037509694 0.018694115405466644 0.010793054660689312 2.663216064507936e-08 7.574593598181027 0.048158523695505884 EADDDEEVDDNIPEMPS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 EADDDEEVDDNIPEMPSPK 19 0 P26358;P26358-2;P26358-3 P26358 DNMT1 DNA (cytosine-5)-methyltransferase 1 1 EADDDEEVDDNIPEMPS(1)PK;EADDDEEVDDNIPEMPS(1)PK 145.79 4.8823e-05 20528200.0 138206.0 129142.0 110647.0 136817.0 127993.0 121176.0 121056.0 111020.0 122508.0 127735.0 True False 182152.63313661749 170884.6259905473 109179.7484845346 105275.95445157848 110223.38126999911 113598.84556413686 131829.74948345395 93864.40998580317 128983.52277496114 123263.0365295078 1.4777555240010023 1.3863412001021038 0.8857460562266628 0.8540756208482386 0.8942127694835171 0.9215970072012835 1.0694994476458106 0.7614968171202977 1.046408772706844 1.0 16.91138071123769 -5.2206064099389025 5.039703612502224 0.9208303634507112 1.4472784452310137 0.8374416936855594 0.0887222405062779 0.06682213022070592 4.23616543364135 0.021848400963734815 0.059075095139561155 6.017188129329274e-06 5.2206064099389025 0.5264480817803024 EADDDEEVDDNIPEMPS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 EADDDEEVDDNIPEMPSPK 19 0 P26358;P26358-2;P26358-3 P26358 DNMT1 DNA (cytosine-5)-methyltransferase 1 1 EADDDEEVDDNIPEMPS(1)PK;EADDDEEVDDNIPEMPS(1)PK;EADDDEEVDDNIPEMPS(1)PK;EADDDEEVDDNIPEMPS(1)PK 181.51 1.8947999999999997e-09 21477700.0 140362.1 132614.0 106677.8 120394.0 118789.1 114120.5 123721.6 112402.2 105669.4 111468.7 True False 138360.510714743 132306.94043078003 97907.16307221632 129248.17638261082 111802.15868635634 109239.83224287878 130127.29907356191 117624.81655640528 93767.79942388771 130735.9162722935 1.0583205798364481 1.0120167755218423 0.7488926215830218 0.9886202664722673 0.8551755468137585 0.8355762927102357 0.9953446825012954 0.89971310034971 0.7172305981211046 1.0 16.996296012736927 -5.040245865570191 14.24392146574954 0.8818923894447441 1.0467592458301531 0.313390291092853 0.09291088897504819 3.5149835052635754 1245.0015160396056 0.02262501360532754 0.060210176088002526 9.114946720673298e-06 5.040245865570191 0.164866856385409 EADDDEEVDDNIPEMPS(ph)PKK ddPTM_PC-9_Lapatinib_30min_R1 7 EADDDEEVDDNIPEMPSPKK 20 1 P26358;P26358-2;P26358-3 P26358 DNMT1 DNA (cytosine-5)-methyltransferase 1 1 EADDDEEVDDNIPEMPS(1)PKK;EADDDEEVDDNIPEMPS(1)PKK;EADDDEEVDDNIPEMPS(1)PKK;EADDDEEVDDNIPEMPS(1)PKK;EADDDEEVDDNIPEMPS(1)PKK;EADDDEEVDDNIPEMPS(1)PKK;EADDDEEVDDNIPEMPS(1)PKK 151.41 6.1471e-06 64320600.0 500853.0 406406.0 395309.0 390661.0 396109.0 397617.0 366922.4 349984.0 404559.0 340768.8 True False 493710.74437480915 405464.9918765111 362808.2199568689 419391.51314689236 372810.64740025706 380611.8478004978 385919.84650690854 366245.5343194084 358993.3052248673 399670.23303411534 1.2352952598615634 1.0144988502105963 0.907768930406934 1.0493438802361186 0.9327956314635881 0.9523147243442802 0.9655956701533159 0.9163693066132002 0.8982237743840785 1.0 18.608450600977363 -4.780713390933114 3.1068569610965557 0.9529661637299209 1.2791209024692214 0.7936722237577041 0.04314230020764499 0.15190718085854882 2.1785572350184976 0.010849198510341518 0.12344304243606218 1.6568630358639277e-05 4.780713390933114 0.32615473873930045 EADDIVNWLK ddPTM_PC-9_Lapatinib_30min_R1 2 EADDIVNWLK 10 0 P07237;I3L312;I3L3P5 P07237 P4HB Protein disulfide-isomerase 0 ; 163.77 2.3294999999999998e-08 12043000.0 126030.0 121646.0 120796.0 106051.0 120128.0 105468.0 118408.0 107667.0 123158.0 108785.0 False True 124232.78908892887 121364.33616090807 110864.61916604418 113850.34431576525 113062.30722073508 100957.37949791607 124538.5868652065 112669.60187770748 109286.64912876539 127588.34230309902 0.9737001582307677 0.9512180656175845 0.8689243638158889 0.8923256017019348 0.8861491981151705 0.7912743255028865 0.976096911498015 0.8830712888333436 0.856556697547993 1.0 16.96113699108008 -3.410603079277946 0.0012309943572888585 1.7962010303957958 2.9325662281059473e-05 0.0034224895418196732 0.06188434465096846 9565994.46805347 1276.4485999334815 919256.3939955551 943370.0276531813 0.0003885052757460018 3.410603079277946 -1.7961717047335148 EADGSETPEPFAAEAK ddPTM_PC-9_Lapatinib_30min_R1 1 EADGSETPEPFAAEAK 16 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 186.51 2.6346999999999996e-07 2331400.0 14335.0 12008.0 15059.0 15470.0 12761.0 12262.0 11889.0 13339.0 12123.0 11518.0 False True 14130.580271282959 11980.196213769328 13820.90714942103 16607.715406407162 12010.423069091288 11737.582844118093 12504.554246676233 13958.778636413599 10757.580079150548 13508.870953229716 1.0460223004724614 0.8868391929456613 1.0230986140345586 1.229393297478837 0.8890767489506458 0.868879633594535 0.925655022538107 1.0333046103365373 0.796334506147504 1.0 13.721619481434104 EADLPMTAASHSSAFTPVTAAAS(ph)PVSLPR ddPTM_PC-9_AZD4547_30min_R2 1 EADLPMTAASHSSAFTPVTAAASPVSLPR 29 0 Q9Y4B6-3;Q9Y4B6-2;Q9Y4B6 Q9Y4B6-3 VPRBP Protein VPRBP 1 EADLPMTAAS(0.001)HS(0.003)S(0.001)AFT(0.011)PVT(0.119)AAAS(0.802)PVS(0.063)LPR 50.92 0.008095699999999999 3637200.0 2018.8 1612.4 8767.8 20649.0 9578.0 6950.2 4435.7 10588.0 5500.8 8916.6 True False 2660.7364063514156 2133.576767799463 8651.533243221245 15888.692073869803 8248.260028314458 6515.602895291688 4830.468706910487 8951.867888035327 5791.561057894225 8604.432548001816 0.30922857393650105 0.24796251884093598 1.0054740036552867 1.8465705884997135 0.9586059257597329 0.757237953687578 0.5613930587476397 1.0403786464819456 0.6730904130614846 1.0 13.070864336058541 -5.262138131546494 24.794001255558925 0.9890156564073493 0.2785954869103607 0.42216834125293057 0.3282716007311471 53.44140767885307 1896374.2439856343 0.09300902436961225 0.21416417496851714 5.4684200685949614e-06 5.262138131546494 -0.7104201694969887 EADLVFISVNT(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 1 EADLVFISVNTPTK 14 0 O60701;E7ER83;E7ETF4;E7EV97 O60701 UGDH UDP-glucose 6-dehydrogenase 1 EADLVFIS(0.3)VNT(0.697)PT(0.003)K 171.71 0.00051871 7052600.0 41438.0 58711.0 65518.0 53582.0 48278.0 60727.0 61292.0 83939.0 52110.0 52783.0 True False 54614.422036056036 77688.18259381926 64649.18851129929 41229.49773364774 41575.43303893983 56929.73109009501 66746.86926166278 70968.15627633128 54864.42821532654 50935.08323589485 1.0722358454411691 1.5252391408496029 1.2692467431905534 0.8094518574300197 0.8162435476230044 1.1176919222147383 1.3104301597494021 1.3933059841613997 1.0771441750911406 1.0 15.636372082515635 -1.5228787468666216 0.010809180878167764 2.0876238673611843e-08 2.4618887059370933 0.023543683700673168 0.22118786203788504 76356.36241979893 64.02322762848176 6208.890802632647 8545.424280438298 0.02999999989042338 1.5228787468666216 2.461888685060855 EADLVFISVNT(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EADLVFISVNTPTK 14 0 O60701;E7ER83;E7ETF4;E7EV97 O60701 UGDH UDP-glucose 6-dehydrogenase 1 EADLVFIS(0.188)VNT(0.81)PT(0.002)K;EADLVFISVNT(0.982)PT(0.018)K 136.81 0.00015007 11844000.0 50884.0 76594.0 61824.0 63184.0 60719.0 44771.0 56942.0 43083.0 40016.0 40765.0 True False 59497.656195189425 84197.74612788855 63298.11862882568 59644.005325291815 48821.547824988535 42423.12994515893 51548.04153562039 41952.11690021179 40601.15829716566 48155.37180443758 1.2355351846687774 1.7484600984874883 1.31445602550602 1.238574287568797 1.0138338880085143 0.880963605004283 1.0704525705867391 0.8711824938364581 0.8431283318099978 1.0 15.555409121405338 -6.007845846263338 1.541290572378881 0.9309282993447895 1.4912710368978876 0.727466686667946 0.13653193328462498 0.1872519055413273 0.8985516612134061 0.045155767795704335 0.07741729568415591 9.820964783631847e-07 6.007845846263338 0.5603427375530982 EADLVFISVNT(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 2 EADLVFISVNTPTK 14 0 O60701;E7ER83;E7ETF4;E7EV97 O60701 UGDH UDP-glucose 6-dehydrogenase 1 EADLVFIS(0.002)VNT(0.996)PT(0.002)K;EADLVFIS(0.057)VNT(0.928)PT(0.015)K 203.2 3.0576e-10 12555200.0 40138.0 68774.0 72254.0 64689.0 72567.0 72237.0 74007.0 74124.0 62687.0 62367.0 True False 39565.62475959229 68614.75802846208 66313.5550285056 69446.4448561781 68298.75173221134 69147.59190267164 77838.72034096786 77568.07164296597 55626.529936625404 73147.05285119604 0.5409052479541606 0.9380385860254128 0.9065786309040786 0.9494086521497164 0.9337184352615319 0.9453230062917155 1.0641402121739085 1.060440149253363 0.7604753406782792 1.0 16.158512117835045 -4.759663704683705 5.422406706476418 0.9555172292300121 0.5192563443535861 0.6968973103897583 0.08114577064648909 0.0872424652186607 7.8757855718972625 0.02011441826515942 0.14350889207144338 1.7391470134980273e-05 4.759663704683705 -0.436260884876426 EADLVFISVNTPTK ddPTM_PC-9_Lapatinib_30min_R1 1 EADLVFISVNTPTK 14 0 O60701;E7ER83;E7ETF4;E7EV97 O60701 UGDH UDP-glucose 6-dehydrogenase 0 157.03 0.0017312999999999999 8128600.0 68447.0 55051.0 70456.0 60303.0 55924.0 57661.0 62522.0 53222.0 59203.0 64439.0 False True 67470.93322835762 54923.53279182336 64663.37964802495 64737.8837849109 52634.66027081434 55194.973444356074 65759.0832375045 55694.888416463386 52534.9347047719 75577.19529042985 0.8927419570027534 0.726720971594168 0.8555937991550887 0.856579600977975 0.6964357445198728 0.7303125398111363 0.8700916061360033 0.7369271670169518 0.6951162252434666 1.0 16.205663359967012 -4.735697062219885 23.436101330508656 0.7890398071457394 0.8927430274690269 0.08241573273342828 0.0935468177239592 2677.4304880376862 2437281.0282121967 0.022206583941321984 1.4305939084039863 1.8378198492337037e-05 4.735697062219885 0.10370322032328749 EADQPTTEPGMVLDSVEAGDT(ph)TPPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EADQPTTEPGMVLDSVEAGDTTPPTK 26 0 A0A0J9YVR0;A0A0J9YWV8 A0A0J9YVR0 1 EADQPTTEPGMVLDSVEAGDT(0.484)T(0.484)PPT(0.032)K 130.29 3.2279000000000003e-10 2545500.0 28246.0 29494.0 32522.0 32397.0 39018.0 32830.0 36482.0 31268.0 27013.0 30569.0 True False 33027.48991607028 32421.969400944567 33297.447820371824 30581.901122491123 31372.702993056595 31108.337006088044 33026.160853192756 30447.248131184493 27408.014021424824 36110.91771592915 0.9146123113204979 0.8978439610977451 0.92208810870746 0.8468879512580462 0.8687871972640993 0.8614662538018417 0.9145755063052398 0.8431590792208996 0.7589952223599866 1.0 15.140147464676657 -5.75629894561707 24.996243963373246 0.8654000686933481 0.910147716099524 0.09162107796094332 0.057476564805385905 286.674257512312 1393984.260369874 0.01520320122951462 0.025346037175423965 1.7526736376133416e-06 5.75629894561707 0.04474764740617598 EADQPTTEPGMVLDSVEAGDTTPPT(ph)KR ddPTM_PC-9_AZD4547_30min_R2 1 EADQPTTEPGMVLDSVEAGDTTPPTKR 27 1 A0A0J9YVR0;A0A0J9YWV8 A0A0J9YVR0 1 EADQPTTEPGMVLDS(0.053)VEAGDT(0.181)T(0.345)PPT(0.42)KR 45.56 0.016606 5517700.0 10044.0 10392.0 12479.0 13424.0 17311.0 15871.0 14656.0 16985.0 12676.0 14285.0 True False 13237.783071821677 13751.010773363932 12313.52030636625 10329.304198732543 14907.666459610751 14878.583861065068 15960.35560756591 14360.358526471478 13346.027481433099 13784.886498015605 0.9603113579301008 0.9975425459863925 0.8932623644118387 0.7493209465467483 1.0814500693753826 1.079340324144628 1.1578155257109644 1.0417465917139554 0.9681637555270635 1.0 13.7507997680855 -6.310436461057577 24.999880086414645 1.0632226202463178 0.9065795465528718 0.4900505796399208 0.07687871195056352 341.55585981254205 174271.80936633924 0.025387378945142633 0.02878662214436636 4.8928684443335e-07 6.310436461057577 -0.156643073693446 EADSSGLAFASNS(ph)LQR ddPTM_PC-9_AZD4547_30min_R2 2 EADSSGLAFASNSLQR 16 0 Q9NPB6-2 Q9NPB6-2 1 EADSSGLAFAS(0.009)NS(0.991)LQR;EADSSGLAFAS(0.004)NS(0.996)LQR 184.22 7.707399999999999e-08 6978300.0 21246.3 17368.3 29729.0 40384.0 29243.0 33657.0 25627.0 35148.0 25746.6 25792.3 True False 28002.181449506686 22982.26331938192 29334.77403541647 31074.09272658038 25183.114220922944 31552.422469401245 27907.753353922737 29716.68422068997 27107.512713274355 24889.319427565126 1.125068185612743 0.92337853537003 1.1786089258402126 1.2484910572591055 1.0118040508987336 1.2677093305515086 1.1212742652583207 1.1939532660655436 1.0891222956965454 1.0 14.603239161419198 -5.284186796824292 24.80431018157061 1.149147202752199 1.0242233286497078 0.17892564663493593 0.09624398379678858 887.44864411275 967693.7156264365 0.023367472858841297 0.04870705488456522 5.197723862448742e-06 5.284186796824292 -0.12492387410249117 EADSSGLAFASNS(ph)LQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EADSSGLAFASNSLQR 16 0 Q9NPB6-2 Q9NPB6-2 1 EADSSGLAFASNS(1)LQR 166.62 5.0021e-21 0.0 7991.3 9083.9 11417.0 10446.0 10208.0 11134.0 9217.6 8013.2 8015.3 8927.7 True False 9344.069254630474 9985.689558596332 11689.22457921362 9860.744486388934 8207.815678741137 10550.1134397132 8344.442198355073 7802.861990687211 8132.508599042182 10546.221338365687 0.8860111081338725 0.9468499890353886 1.10838035768222 0.9350026108893539 0.7782707583504098 1.0003690517411532 0.7912257794172356 0.7398727696242714 0.7711300889786228 1.0 13.364438560197547 -6.0116716876434815 24.1316842087995 0.8403339057646997 0.9844964374857303 0.27323742519071836 0.09935461787485345 447.40132739451326 925025.363194763 0.029321134950149475 0.04017633181684277 9.734828667376052e-07 6.0116716876434815 0.14416253172103066 EADSSGLAFASNS(ph)LQR ddPTM_PC-9_Lapatinib_30min_R1 1 EADSSGLAFASNSLQR 16 0 Q9NPB6-2 Q9NPB6-2 1 EADSSGLAFASNS(1)LQR 181.51 2.4972e-06 2973500.0 10189.0 8510.9 9121.2 9040.1 9940.9 9124.0 8406.8 8754.1 9910.8 7084.3 True False 10043.702991566246 8491.193533958138 8371.290144850196 9704.939110889554 9356.195806561367 8733.787789082824 8842.062969211682 9160.847444413255 8794.541338649276 8308.811815763615 1.2088013562313649 1.0219503970289117 1.0075195263139847 1.1680297166530098 1.126057012003887 1.0511476228782721 1.0641789903625418 1.102546025537989 1.058459564815769 1.0 13.020426466824187 -14.522878745234413 0.17395884405046455 0.6470569346926023 1.1070465427229759 0.20160578655800188 0.05895326489514313 248.33653610321267 2.3553572770641944 30.129865978152324 0.20508659613972702 3.000000000317234e-15 14.522878745234413 0.4599896080303736 EAEALLQSMGLTPESPIVPPPMS(ph)PSSK ddPTM_PC-9_AZD4547_30min_R2 9 EAEALLQSMGLTPESPIVPPPMSPSSK 27 0 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E9PGG1;E7ETL8 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 1 EAEALLQSMGLTPESPIVPPPMS(0.52)PS(0.24)S(0.24)K;EAEALLQSMGLTPESPIVPPPMS(0.718)PS(0.2)S(0.082)K;EAEALLQSMGLTPES(0.001)PIVPPPMS(0.333)PS(0.333)S(0.333)K;EAEALLQSMGLTPESPIVPPPMS(0.685)PS(0.183)S(0.131)K;EAEALLQSMGLTPESPIVPPPMS(0.67)PS(0.14)S(0.19)K;EAEALLQSMGLTPESPIVPPPMS(0.717)PS(0.114)S(0.169)K;EAEALLQSMGLTPES(0.004)PIVPPPMS(0.7)PS(0.148)S(0.148)K;EAEALLQSMGLTPESPIVPPPMS(0.66)PS(0.136)S(0.204)K;EAEALLQSMGLTPESPIVPPPMS(0.745)PS(0.178)S(0.077)K 141.21 1.5063e-12 281796400.0 798421.0 795789.0 1049013.0 1360273.0 1174664.0 1086016.0 858713.0 1129418.0 958160.0 1017555.0 True False 1052302.2698115227 1053012.2317479313 1035102.4022070809 1046683.075858351 1011582.1797765716 1018107.2478393574 935136.7934524919 954892.3995437359 1008806.3814775903 981930.7091696375 1.071666523905128 1.0723895504178735 1.054150147806669 1.0659439266783608 1.0301971109876058 1.036842252036615 0.9523449920853208 0.9724641368546602 1.0273702330082741 1.0 19.9052616974856 -6.799322485287545 1.7009928880149707 0.9870579588974786 1.0647837650753196 0.7039190559940567 0.02154310957619572 0.19572477186702553 1.1712453008258716 0.009410382279064997 0.008332134138578123 1.587367611340455e-07 6.799322485287545 0.07772580617784097 EAEALLQSMGLTPESPIVPPPMS(ph)PSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 EAEALLQSMGLTPESPIVPPPMSPSSK 27 0 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E9PGG1;E7ETL8 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 1 EAEALLQSMGLTPESPIVPPPMS(0.7)PS(0.133)S(0.167)K;EAEALLQSMGLTPESPIVPPPMS(0.695)PS(0.152)S(0.152)K;EAEALLQSMGLTPES(0.003)PIVPPPMS(0.593)PS(0.182)S(0.223)K;EAEALLQSMGLTPESPIVPPPMS(0.597)PS(0.165)S(0.238)K;EAEALLQSMGLTPES(0.002)PIVPPPMS(0.332)PS(0.332)S(0.332)K;EAEALLQSMGLTPESPIVPPPMS(0.602)PS(0.161)S(0.237)K;EAEALLQSMGLTPESPIVPPPMS(0.711)PS(0.12)S(0.168)K 107.43 3.3098000000000003e-10 204650800.0 440599.0 455493.0 481595.0 568870.0 706946.0 657896.0 681227.0 654787.0 630842.0 571364.0 True False 515183.7084730814 500711.3347916326 493078.05125920835 536998.0582014238 568425.0061543237 623394.7756002838 616696.2469036212 637599.5350541743 640066.8708141873 674947.7702850653 0.7632941853493237 0.7418519726054601 0.7305425293144624 0.7956142413428847 0.8421762856024377 0.9236192829216874 0.9136947687717504 0.9446649994634149 0.9483205945607526 1.0 19.36441634035417 -6.532298635159997 1.017942328044112 0.9571734993869989 0.7384174599244451 0.9503859796076604 0.02065999679139423 0.10402651094531222 0.23182861456782322 0.010408721391086392 0.012004856416227212 2.93563032186563e-07 6.532298635159997 -0.21875603946255384 EAEALLQSMGLTPESPIVPPPMS(ph)PSSK ddPTM_PC-9_Lapatinib_30min_R1 8 EAEALLQSMGLTPESPIVPPPMSPSSK 27 0 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E9PGG1;E7ETL8 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 1 EAEALLQSMGLTPESPIVPPPMS(0.874)PS(0.063)S(0.063)K;EAEALLQSMGLTPESPIVPPPMS(0.644)PS(0.158)S(0.197)K;EAEALLQSMGLTPES(0.001)PIVPPPMS(0.333)PS(0.333)S(0.333)K;EAEALLQSMGLTPESPIVPPPMS(0.797)PS(0.12)S(0.083)K;EAEALLQSMGLTPESPIVPPPMS(0.677)PS(0.139)S(0.184)K;EAEALLQSMGLTPESPIVPPPMS(0.677)PS(0.149)S(0.175)K;EAEALLQSMGLTPESPIVPPPMS(0.646)PS(0.177)S(0.177)K;EAEALLQSMGLTPESPIVPPPMS(0.624)PS(0.188)S(0.188)K 123.97 5.1632e-12 325369800.0 1337181.0 1128887.0 1347675.0 1135098.0 1430901.0 1553381.0 1438699.0 1499925.0 1624357.0 1270696.0 True False 1318112.5537310382 1126273.131510109 1236874.3636759415 1218576.893495927 1346738.2164396038 1486946.5157379734 1513187.7946117301 1569616.9912454244 1441404.80942248 1490334.1105040119 0.8844409749739067 0.7557185489965186 0.8299309228436343 0.8176534945468168 0.9036485221318287 0.997726956162271 1.0153346044666383 1.0531980581955547 0.9671689047867362 1.0 20.507204366811905 -6.570582669834001 2.106690509978851 1.0138731307328235 0.8161919171213485 0.8580902257845323 0.03544723734495076 0.10300189933558372 0.9265600141049175 0.012578844618838536 0.013149141552952956 2.687926135991547e-07 6.570582669834001 -0.19768121361147495 EAEALLQSMGLTPESPIVPPPMSPSS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 EAEALLQSMGLTPESPIVPPPMSPSSK 27 0 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E9PGG1;E7ETL8 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 1 EAEALLQSMGLTPESPIVPPPMS(0.313)PS(0.313)S(0.373)K 68.32600000000001 0.00014253 15235000.0 97313.0 77071.0 108450.0 132580.0 129880.0 108820.0 91509.0 104150.0 99674.0 100860.0 True False 128256.50976385715 101982.6935444508 107011.8821400288 102015.72934058098 111848.4038919901 102015.46819741014 99653.12372357748 88056.01062890822 104942.564151496 97328.92209939468 1.3177635896643185 1.0478148873394855 1.0994869750098089 1.048154311586848 1.149179519092668 1.0481516284874648 1.0238798660670387 0.9047260437034663 1.0782258951180625 1.0 16.57058095710645 -2.4425294185840034 1.3736566764878524 1.0400980483977762 199.99999989763148 0.6295370425632589 0.062176130408833144 702.7319527038874 2.4636157579721045 0.01871455970972563 439374.247512876 0.0036096956111586185 2.4425294185840034 198.95990184923372 EAEAMALLAEAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAEAMALLAEAER 13 0 M0QZM9;M0QZN5;M0R031;M0R0Y2;M0R2M1;P54920 M0QZM9 NAPA Alpha-soluble NSF attachment protein 0 58.781000000000006 0.043445 83907000.0 91274.0 52269.0 90040.0 135690.0 162050.0 155510.0 129250.0 97618.0 87659.0 100240.0 False True 106724.8854563266 57457.92088621315 92186.89507860174 128087.72921291534 130297.46578565857 147354.78184029105 117006.50431103441 95055.63093482042 88940.84704046477 118412.71850059637 0.9012957966655338 0.4852343702076544 0.7785219041157091 1.081705840680199 1.1003671517346538 1.244416847330035 0.9881244666335831 0.8027484896763154 0.7511089025459442 1.0 16.853464521048018 -5.611074991823391 5.145130623415087 1.0004640767355477 0.6791129773012579 0.37741831720308006 0.1628911717238864 0.20826093277724042 9.165020360825865 0.0481935800213887 0.08556533690753287 2.4486403862250117e-06 5.611074991823391 -0.32135109943428986 EAEAYTGLS(ph)PPVPSFNCEVR ddPTM_PC-9_Lapatinib_30min_R1 1 EAEAYTGLSPPVPSFNCEVR 20 0 O43164-2;O43164 O43164-2 PJA2 E3 ubiquitin-protein ligase Praja-2 1 EAEAYT(0.229)GLS(0.766)PPVPS(0.004)FNCEVR 145.99 2.0059e-14 0.0 5267.6 5115.2 4732.7 4665.4 6684.4 5129.0 5681.5 6253.5 5215.9 4802.3 True False 5192.483058040469 5103.356068676949 4343.595674750311 5008.5090793181635 6291.236734036036 4909.644626282964 5975.660270206995 6544.060439524136 4628.430416138028 5632.371156337475 0.9219000158038148 0.9060759539851551 0.7711842054057376 0.8892363340939722 1.1169783665547703 0.8716834331414207 1.0609493061342832 1.161865981108301 0.821755223096435 1.0 12.45952669103863 -6.076386455381027 9.020097931422194 1.0094009567507942 0.8637330302096282 0.2896452927648966 0.10270663462305417 0.49031748722580004 54.85591621672876 0.02961325049480373 0.03832174690652974 8.38713328327722e-07 6.076386455381027 -0.145667926541166 EAEEES(ph)DHN ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAEEESDHN 9 0 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 EAEEES(1)DHN 72.848 0.031181999999999998 2956700.0 4957.8 9060.4 7546.5 6902.4 14092.0 13835.0 6737.4 10524.0 9539.6 10865.0 True False 5797.0576189865205 9959.856633902431 7726.437180260625 6515.68090588273 11330.773760268426 13109.468244874444 6099.1846974480795 10247.756151099717 9679.098602849897 12834.73849270733 0.4516693209043874 0.7760077573502256 0.6019941259146627 0.5076598100993585 0.8828207732246782 1.0214051694409836 0.47520911321361337 0.7984390298970616 0.7541329033193422 1.0 13.647766280907444 -6.263704451367745 24.99020497759129 0.8045537149770847 0.5992853511121972 0.33490603741089386 0.16242565968018607 284.0390573209652 3133756.104073523 0.05009048280477723 0.05955383645804187 5.448733270990304e-07 6.263704451367745 -0.20526836386488756 EAEEES(ph)DHN ddPTM_PC-9_Lapatinib_30min_R1 1 EAEEESDHN 9 0 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 EAEEES(1)DHN 80.916 0.017991 1901900.0 9838.8 6218.8 3490.1 4937.9 5608.4 3897.0 7758.5 8307.2 5055.1 3459.4 True False 9698.49690778505 6204.400750681936 3203.1574501756004 5301.049638351513 5278.524938538641 3730.3343943506943 8160.197167367941 8693.182838924595 4485.741405437097 4057.35268063925 2.3903509680250465 1.5291746217399103 0.7894698100710663 1.3065291720009693 1.3009775964821948 0.9194010696065413 2.0112121892451 2.1425751033195746 1.1055833097383962 1.0 11.98632299723702 -7.270109153331537 24.96459494613763 1.6600571953849828 1.3469936727809209 0.017506152671997843 0.521388319661785 1904.146649506108 5482962.130098544 0.21965741490579116 0.15066981612981434 5.3689683853334635e-08 7.270109153331537 -0.3130635226040619 EAEEGEDDRDS(ph)ANGEDDS ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAEEGEDDRDSANGEDDS 18 1 P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3 P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 EAEEGEDDRDS(0.996)ANGEDDS(0.004) 110.37 0.0010957 13254000.0 5045.9 8016.5 6655.0 4892.1 5465.0 4257.0 5500.4 3458.2 3791.4 3155.0 True False 5900.0712089322005 8812.325140797182 6813.680439228048 4618.011497402194 4394.172480830754 4033.7554259798007 4979.362292552534 3367.4259142657747 3846.842052375897 3726.9765250337414 1.5830717390630158 2.3644702566827682 1.8282058911456014 1.2390771625159045 1.1790180193826072 1.0823130757292017 1.3360326417691764 0.9035275354290804 1.032161599767809 1.0 11.863790016708709 -5.756267080782673 3.1780629694028084 1.103660815452232 2.002080216061121 0.7693527582838681 0.206464524926175 0.10364229706034155 2.16221528478009 0.05711805710285403 0.0993939040375027 1.752802238612068e-06 5.756267080782673 0.8984194006088888 EAEEVISSS(ph)TK ddPTM_PC-9_AZD4547_30min_R2 1 EAEEVISSSTK 11 0 Q5JRV8 Q5JRV8 TMEM255A Transmembrane protein 255A 1 EAEEVIS(0.014)S(0.121)S(0.432)T(0.432)K 77.67399999999999 0.019239 2936900.0 1170.1 1525.4 12660.0 23988.0 17343.0 9103.6 3837.1 21955.0 4517.3 5437.6 True False 1542.1674604080604 2018.4557191771905 12492.120128102946 18457.93721090555 14935.22381197095 8534.35045287581 4178.5944665523475 18562.35922570981 4756.075255749273 5247.231279076626 0.29390117919091246 0.3846706218621995 2.380706979300754 3.5176526875243166 2.8463056072114195 1.6264483113040196 0.7963427271091564 3.537553090089121 0.9063971078831914 1.0 12.357340664851199 -5.256524312798705 23.291285908514677 2.184232960928504 0.3392851797648538 0.3358715988036769 0.9676353021451463 166.09128328427437 787044.9357051675 0.24942258124099176 0.6152784605321431 5.539565313165216e-06 5.256524312798705 -1.8449477811636503 EAEGELPESGGPAAPPDAELS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 EAEGELPESGGPAAPPDAELSPR 23 0 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 EAEGELPESGGPAAPPDAELS(1)PR;EAEGELPES(0.001)GGPAAPPDAELS(0.999)PR;EAEGELPES(0.031)GGPAAPPDAELS(0.969)PR 206.95 3.273399999999999e-30 17745100.0 56568.0 48048.0 63938.0 73779.0 64064.0 64790.0 54230.0 71532.0 49320.0 59822.0 True False 74555.44731250578 63578.57637014916 63090.14034365293 56770.39142418707 55169.819425134425 60738.67105780388 59056.36494256959 60478.373041834464 51926.95451122441 57727.64998839968 1.2915032454549533 1.101353967863324 1.0928929266362104 0.983417676548327 0.9556914136678134 1.0521590792282252 1.0230169590211435 1.0476500092068106 0.8995161681041768 1.0 15.816974876000481 -3.499935424991866 0.8058754198844084 0.9975561608312885 3.2389494631231073 0.7862234992644843 0.04663489600294719 7.404310701647776 0.738637541068176 0.016770453290443285 23.723077995198928 0.00031627478924563495 3.499935424991866 2.2413933022918187 EAEGGRPPAAT(ph)SPAEVVWSSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAEGGRPPAATSPAEVVWSSEK 22 1 O75564;O75564-2 O75564 JRK Jerky protein homolog 1 EAEGGRPPAAT(0.555)S(0.436)PAEVVWS(0.007)S(0.002)EK 49.125 0.03165 2711000.0 20045.0 20158.0 24258.0 22159.0 24729.0 25152.0 27572.0 20702.0 22466.0 16705.0 True False 23438.222593203587 22159.1530204191 24836.40271897729 20917.503070447307 19883.529968611834 23832.98484243455 24960.18055600656 20158.594435582127 22794.522748503674 19733.48426329277 1.187738682154686 1.1229214630706874 1.258591862825599 1.0600004941528238 1.0076036093432408 1.2077433728602842 1.2648643403758264 1.0215425804494205 1.1551190070830468 1.0 14.268358089061131 -14.522878744166938 0.22252537011829487 0.2685987659412167 1.158446212309175 0.20346420843258817 0.08621073586393142 272.34598777696664 2.7188037853216587 89.27758875950835 0.16657675838718836 3.00000000769109e-15 14.522878744166938 0.8898474463679583 EAEMEEHR ddPTM_PC-9_Lapatinib_30min_R1 2 EAEMEEHR 8 0 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73;H7C044 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 0 ; 85.161 0.0091152 1757170.0 10141.5 12931.8 10381.8 12152.1 13394.3 11299.099999999999 11590.2 11807.5 13263.099999999999 11542.2 False True 9996.880350276675 12901.857211627426 9528.248478906919 13045.805972217224 12606.473608207001 10815.863832488563 12190.28384471585 12356.119555397978 11769.270011365299 13537.25389098524 0.7384718075601597 0.9530631039001981 0.7038538654617383 0.9636966313311681 0.931243050453677 0.7989703022184647 0.9004990186993267 0.9127493400730405 0.8693986318157717 1.0 13.724647489240292 -14.522878745267361 0.026761618787239788 1.8201063515548546 0.28656080311261056 0.2555538623159893 0.08117740388855336 2736.982149643053 5.505062451094875 234.98357324995408 104.65153395311256 3.000000000089638e-15 14.522878745267361 -1.533545548442244 EAENPEGEEK ddPTM_PC-9_Lapatinib_30min_R1 2 EAENPEGEEK 10 0 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 0 ; 110.38 0.0080524 6773400.0 62096.0 61464.0 55192.0 45687.0 61017.0 46838.0 56500.0 49233.0 56662.0 65249.0 False True 61210.499652988285 61321.68388433689 50654.32680728109 49046.974387364215 57428.1000240376 44834.847924710775 59425.29354337681 51520.54491390293 50280.12888268812 76527.20271117256 0.799852829901646 0.8013057019185186 0.6619126926468178 0.6409090186201674 0.7504272727801327 0.5858681140342417 0.7765250974566333 0.6732317801860698 0.6570229552549357 1.0 16.22368504553171 -11.29011773393263 5.755243269934736 1.013548657148737 0.7038631195894898 0.615046175740188 0.06995371552729335 0.01245216639748605 0.0005036060513970536 0.0693535742928565 0.016603247527184554 5.1272237001249464e-12 11.29011773393263 -0.3096855375592473 EAENQGLDIS(ph)SPGMSGHR ddPTM_PC-9_AZD4547_30min_R2 1 EAENQGLDISSPGMSGHR 18 0 Q15545 Q15545 TAF7 Transcription initiation factor TFIID subunit 7 1 EAENQGLDIS(0.5)S(0.5)PGMS(0.001)GHR 99.92299999999999 0.0018100000000000002 0.0 25981.0 19417.0 37571.0 43052.0 42635.0 40365.0 32953.0 41302.0 32843.0 37695.0 True False 34242.41756162873 25693.165529869846 37072.7839915447 33127.02654676946 36715.86618366957 37840.97016898063 35885.75316158022 34919.72492554166 34579.013929686604 36375.309523465054 0.9413642938086773 0.706335310034837 1.0191743926640602 0.9107008842192756 1.0093623027450758 1.0402927333049938 0.9865415203802176 0.9599842690827298 0.9506177234692754 1.0 15.15067190375094 -5.281109265891275 24.998646991210695 0.9834608333303483 0.8238497823363371 0.5081421006492057 0.06324744937310729 526.5734298256438 669226.5147854609 0.015614968906880154 0.03257374245171386 5.234687184214489e-06 5.281109265891275 -0.15961105099401118 EAENQGLDIS(ph)SPGMSGHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAENQGLDISSPGMSGHR 18 0 Q15545 Q15545 TAF7 Transcription initiation factor TFIID subunit 7 1 EAENQGLDIS(0.5)S(0.5)PGMSGHR 115.54 9.0034e-05 4009700.0 21650.0 32815.0 39309.0 30862.0 38785.0 31724.0 40893.0 25969.0 31935.0 29152.0 True False 25314.91739300862 36072.656333220184 40246.27564021265 29132.902195953986 31185.35767045212 30060.337593089782 37019.31900031829 25287.34126642992 32401.988959915656 34437.02683289498 0.7351075200495321 1.0474962460685722 1.1686919383460985 0.8459761156885245 0.9055763676050919 0.8729074591414931 1.0749859208216155 0.7343067503805211 0.9409055293055841 1.0 15.071672970640849 EAENQGLDIS(ph)SPGMSGHR ddPTM_PC-9_Lapatinib_30min_R1 1 EAENQGLDISSPGMSGHR 18 0 Q15545 Q15545 TAF7 Transcription initiation factor TFIID subunit 7 1 EAENQGLDIS(0.721)S(0.279)PGMSGHR 133.41 2.0635e-06 0.0 8577.7 10152.0 12817.0 11810.0 15838.0 16961.0 12143.0 10440.0 14164.0 10313.0 True False 8455.380425042476 10128.49366773702 11763.235735050754 12678.546797005078 14906.439978706054 16235.617568022117 12771.705123844675 10925.080513093786 12568.70116646773 12095.588308791284 0.6990466448743926 0.837370899964862 0.9725228268972274 1.0481959598269468 1.2323865196264818 1.3422759731514495 1.0558978032149107 0.9032285354118118 1.0391144974182511 1.0 13.562193320800688 -5.2368401620822445 1.5385563615211832 1.1003124800646924 0.6907537728948028 0.55801753006214 0.11583548443873232 0.4502135540631226 1.7073966542695787 0.03935695012986786 0.21400166307406704 5.796419888476858e-06 5.2368401620822445 -0.4095587071698896 EAENQGLDISS(ph)PGMSGHR ddPTM_PC-9_Lapatinib_30min_R1 3 EAENQGLDISSPGMSGHR 18 0 Q15545 Q15545 TAF7 Transcription initiation factor TFIID subunit 7 1 EAENQGLDIS(0.19)S(0.81)PGMSGHR;EAENQGLDIS(0.346)S(0.653)PGMS(0.001)GHR;EAENQGLDIS(0.018)S(0.982)PGMSGHR 170.5 3.9025e-08 7342500.0 49797.6 49564.3 66180.0 46571.4 70991.0 64765.0 58965.0 63651.0 72484.0 50419.8 True False 49087.47709223857 49449.5369085715 60738.93586218769 49996.41611363613 66815.448953676 61995.151924588885 62017.91918203919 66608.4578293997 64320.088629641876 59134.7952498395 0.8300946487571004 0.8362172676788918 1.027126848170706 0.8454652781396385 1.1298838301779246 1.048370112091614 1.048755118201031 1.126383503113262 1.0876859953246638 1.0 15.85171964976314 -5.582976839995993 0.7555523106521412 1.082039284770522 0.7894068197571839 0.6044385859663812 0.07046268497296482 0.7395136514607202 0.6522487827639917 0.03193166549341654 0.1538161192569134 2.612300659140782e-06 5.582976839995993 -0.29263246501333817 EAET(ph)PQAK ddPTM_PC-9_Lapatinib_30min_R1 1 EAETPQAK 8 0 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 EAET(1)PQAK 95.48299999999999 0.01568 4077600.0 27554.0 34389.0 31226.0 43477.0 38591.0 26578.0 54510.0 42565.0 35136.0 30175.0 True False 27161.07490721524 34309.37438335384 28658.718815845736 46674.443615020355 36321.15325282517 25441.320896344056 57332.26108052157 44542.72529117214 31178.61368151724 35390.70854433986 0.7674634395405229 0.969445817688808 0.8097808717206146 1.318833262593301 1.0262906493471184 0.7188700634368328 1.6199805948697483 1.258599421239787 0.8809830309685542 1.0 15.111083025267739 -5.09976723296486 0.7718513207485879 1.137963442732859 0.6774251650424798 0.15194739308841643 0.24783552073873197 3.5166042402918385 2.1709075644220484 0.10602785993717488 1.290645352213857 7.947540816852065e-06 5.09976723296486 -0.46053827769037925 EAETEPHEGKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAETEPHEGKR 11 1 P41223;P41223-2 P41223 BUD31 Protein BUD31 homolog 0 69.346 0.013866999999999999 1844100.0 7288.3 5166.6 9114.1 6646.6 10213.0 7464.1 9484.7 9166.8 7769.9 4361.5 False True 8522.06523951338 5679.505903130136 9331.414709416733 6274.212550567939 8211.835964633938 7072.669456202917 8586.24055271853 8926.181213027441 7883.520088293363 5152.205424384997 1.6540616178033376 1.1023446146478295 1.8111495836815543 1.2177722031176332 1.5938487090922155 1.372746013334117 1.6665175095854108 1.7324971498186976 1.5301253422430054 1.0 12.330974401180073 -7.243414243877679 24.659253973146676 1.5433264622261609 1.4536765283414286 0.0 0.26824683347843786 3302.108403844672 4517449.489110739 0.09552182008048252 0.07383734215489317 5.7093380206957084e-08 7.243414243877679 -0.0896499338847323 EAFQLFDR ddPTM_PC-9_Lapatinib_30min_R1 2 EAFQLFDR 8 0 F8W1R7;G3V1V0;P60660-2;P60660;J3KND3;G8JLA2;B7Z6Z4;G3V1Y7 F8W1R7 MYL6 Myosin light polypeptide 6 0 ; 112.11 0.01721 47274000.0 66752.0 71239.0 80564.0 68876.0 81478.0 76214.0 82221.0 81173.0 70635.0 65072.0 False True 65800.10423918243 71074.05047241125 73940.33890603318 73941.37080360056 76685.62423191124 72954.50488351136 86478.00106955731 84944.59391660537 62679.34248047507 76319.60849701024 0.8621651176546601 0.9312685412320416 0.9688249240551298 0.9688384447949199 1.0047958282557927 0.9559077453387264 1.1331033108345285 1.1130113949671665 0.8212744236355783 1.0 16.219766150200126 -4.430233945316973 0.651846361789265 1.0162226129337748 0.6966328060820244 0.2229457411538307 0.08091851436500103 7.275483960545201 1.6923021611358158 0.03678482108709617 1.9162882468553653 3.713351447671586e-05 4.430233945316973 -0.3195898068517504 EAFSLFDK ddPTM_PC-9_Lapatinib_30min_R1 2 EAFSLFDK 8 0 P0DP25;P0DP24;P0DP23;E7EMB3;F8WBR5;M0QZ52;G3V479;P27482 P0DP25 CALM2;CALM3;CALM1;CALML3 Calmodulin-like protein 3 0 ; 140.5 0.011398 10320800.0 73542.0 65920.0 69165.0 73215.0 69648.0 64306.0 81962.0 63839.0 64577.0 75365.0 False True 72493.27759404907 65767.36629011271 63478.52068462092 78599.47533808026 65551.44157323653 61555.782284607594 86205.59131685394 66805.1929957274 57303.658234043076 88391.73983244998 0.8201363354931459 0.7440442558860968 0.718149917684016 0.8892174255995939 0.7416014403324549 0.6963974507266063 0.9752675021473729 0.7557854740992684 0.6482920049165727 1.0 16.431623936275223 -11.517174754596923 3.5395078466579553 1.2109294030089288 0.779033496679577 0.3506096925153631 0.09117700739419606 0.07500037311332895 0.00012086469012341885 0.043628242937278704 0.021263650252826196 3.039661658220839e-12 11.517174754596923 -0.4318959063293518 EAFSLFDKDGDGTITTK ddPTM_PC-9_AZD4547_30min_R2 2 EAFSLFDKDGDGTITTK 17 1 P0DP25;P0DP24;P0DP23;E7EMB3;F8WBR5;M0QZ52;G3V479 P0DP25 CALM2;CALM3;CALM1 0 ; 136.34 6.3661e-05 44872000.0 86251.0 76009.0 108000.0 132673.0 106155.0 137167.0 119592.0 124694.0 92748.0 122930.0 False True 113677.02386775092 100577.42281299253 106567.84943405357 102087.28962741682 91417.21061868034 128589.92580623251 130235.45631959783 105425.40748306357 97650.46993120518 118626.25811698014 0.9582787628321828 0.8478512633670934 0.8983495823409056 0.8605791942518 0.7706321692161249 1.0839920928756512 1.0978636466065512 0.8887189831032274 0.8231775281566225 1.0 16.856063862585223 -6.758965317738854 24.99945978190018 0.9792399528042701 0.8674362894134126 0.2878776974699514 0.08776945028011313 96.40453909291546 974133.6546007066 0.03198638466762604 0.03057817295335529 1.7419459776528e-07 6.758965317738854 -0.11180366339085757 EAFSLFDKDGDGTITTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EAFSLFDKDGDGTITTK 17 1 P0DP25;P0DP24;P0DP23;E7EMB3;F8WBR5;M0QZ52;G3V479 P0DP25 CALM2;CALM3;CALM1 0 ; 157.58 3.6346e-05 49380000.0 102028.0 94417.0 116259.0 128215.0 159817.0 137452.0 133681.0 121130.0 116486.0 108161.0 False True 119299.32525514449 103790.095779785 119031.05547471295 121031.52922863833 128502.00610593383 130243.77514958307 121017.76791337242 117950.465847844 118189.38738013916 127769.73309799525 0.9337056778826153 0.8123214572279129 0.931606043063579 0.9472629103467803 1.0057311930625772 1.019363287310699 0.9471552063160037 0.9231487222203071 0.925018660636097 1.0 16.96318659647332 -5.517700500016286 3.9248950340118234 0.9658437192056477 0.8716711443131749 0.44020302181533844 0.04168332652191732 0.19374350309386804 6.725011887486359 0.01182891490932401 0.023907871143000987 3.0359841505657216e-06 5.517700500016286 -0.09417257489247277 EAFSLFDKDGDGTITTK ddPTM_PC-9_Lapatinib_30min_R1 2 EAFSLFDKDGDGTITTK 17 1 P0DP25;P0DP24;P0DP23;E7EMB3;F8WBR5;M0QZ52;G3V479 P0DP25 CALM2;CALM3;CALM1 0 ; 132.15 3.1896999999999996e-05 83855000.0 208367.0 223935.0 270470.0 256230.0 250488.0 176990.0 223116.0 221495.0 213804.0 223163.0 False True 205395.64837017245 223416.49226602557 248233.00064439222 275074.0089582236 235754.78831835566 169420.55028384135 234667.85476502785 231786.46630725186 189723.14206406867 261736.42720399436 0.7847423095222792 0.8535934208802252 0.9484083025666209 1.0509580645564254 0.900733577044708 0.6472945019295955 0.8965807979877803 0.8855720572918195 0.7248633447426125 1.0 17.997755200081173 -6.550673534439824 24.98499049130951 0.821839620028451 0.9166751374504811 0.10449019426133477 0.11031049668501582 435.19108075595915 391194.19902083394 0.0367999322552157 0.03680053401617498 2.814015372345337e-07 6.550673534439824 0.09483551742203011 EAFTNKPNVFTVVTR ddPTM_PC-9_Lapatinib_30min_R1 1 EAFTNKPNVFTVVTR 15 1 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 98.25299999999999 0.0029711 8419700.0 15017.0 13801.0 13417.0 16087.0 18772.0 15445.0 13756.0 13051.0 15267.0 12674.0 False True 14802.854826219476 13769.044632430918 12313.90605111774 17270.091644658827 17667.86786717199 14784.453354053507 14468.218371375067 13657.397105017919 13547.469691362803 14864.684012956537 0.9958405313773795 0.9262924540090711 0.8284001220869911 1.1618203003579262 1.1885801172612958 0.9946025990977609 0.9733283505228972 0.9187815289658153 0.9113863220741452 1.0 13.859601174931843 -10.463741887975539 7.297735154379392 1.0000000001279896 0.9908500720459195 0.0006746043565060145 0.10523308480140359 3.1975553897998945e-10 1.1461910000792802e-10 0.11226773998118418 0.02722892608201038 3.437621936310014e-11 10.463741887975539 -0.009149928082070158 EAGAGGLAIAVEGPSK ddPTM_PC-9_Lapatinib_30min_R1 2 EAGAGGLAIAVEGPSK 16 0 Q60FE5;P21333-2;P21333;H0Y5C6 Q60FE5 FLNA Filamin-A 0 ; 206.49 2.4438e-16 12434400.0 33970.0 38002.0 36833.0 36026.0 39618.0 34618.0 39263.0 31975.0 37362.0 39479.0 False True 33485.58157066496 37914.008703835934 33804.73291949165 38675.472219212985 37287.74713198488 33137.468838499466 41295.846024665545 33460.67523047644 33153.89812069806 46302.89254753914 0.7231855231567951 0.8188259224822652 0.7300782102281054 0.8352711913085109 0.8053005996051237 0.7156673593226872 0.8918632023316284 0.7226476228482355 0.716022181263492 1.0 15.498814701191368 -11.109617315927117 2.7956007574972976 1.0156368946911822 0.7763599859352923 0.5715725620167573 0.05884830460854561 19302124.789420962 19571367.003732916 2234355.9173762617 0.015125329754801126 7.769314180346127e-12 11.109617315927117 -0.23927690875588992 EAGAGGLSIAVEGPSK ddPTM_PC-9_Lapatinib_30min_R1 2 EAGAGGLSIAVEGPSK 16 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;Q14315-2;Q14315 O75369-2;Q14315-2 FLNB;FLNC Filamin-B;Filamin-C 0 ; 204.13 3.3396e-16 9404600.0 43421.0 43577.0 41919.0 44609.0 44635.0 38060.0 44035.0 40291.0 36475.0 45243.0 False True 42801.80857756384 43476.10013386288 38472.5816320194 47889.694671261626 42009.65705578639 36432.262522193334 46314.91683509024 42163.066949526976 32366.80140122216 53063.192267491904 0.80661955582694 0.8193268869822149 0.7250333044057896 0.9025030840558811 0.7916911000004566 0.6865825625141069 0.8728256792696609 0.794582179243621 0.6099670980603824 1.0 15.695423849875672 -6.5130808892839855 24.909537402137428 0.7798641213522232 0.8124376768485336 0.0017720648908645664 0.10522230701487868 2526.0794554570584 6422188.237394678 0.03243835814920789 0.034353328155305375 3.068450422589545e-07 6.5130808892839855 0.03257355549631047 EAGDEFELR ddPTM_PC-9_Lapatinib_30min_R1 2 EAGDEFELR 9 0 Q5QP56;Q9H1R6;Q5TE64;Q07817-2;Q07817-3;Q07817 Q5QP56 BCL2L1 Bcl-2-like protein 1 0 ; 120.87 0.007607200000000001 3547300.0 15464.4 17913.0 18014.0 15907.199999999999 15508.8 17438.2 17000.4 16706.0 14454.1 12876.5 False True 15243.87482017636 17871.52354907144 16532.958456050892 17077.068552863624 14596.602875473951 16692.408836429633 17880.597528403956 17482.22174825141 12826.127049579307 15102.185868142251 1.0093820161711158 1.1833733013954655 1.0947394370855166 1.1307680028549607 0.9665225287860603 1.1052975365401856 1.1839741402019628 1.1575954567695923 0.8492894446912984 1.0 13.882469757768572 -8.256976595998907 24.999960253833567 0.9246447170644885 1.1053210752892522 0.48053136826398624 0.07456324287437732 291.89179357947336 1635165.3068225703 0.0541401802364872 0.018894873905210437 5.533799298928556e-09 8.256976595998907 0.1806763582247637 EAGELPT(ph)SPLHLLSPGTPR ddPTM_PC-9_AZD4547_30min_R2 1 EAGELPTSPLHLLSPGTPR 19 0 H7C228;Q969R5-2;Q969R5-3;Q969R5 H7C228 L3MBTL2 Lethal(3)malignant brain tumor-like protein 2 1 EAGELPT(0.606)S(0.394)PLHLLSPGTPR 118.32 0.00011893 2467100.0 5449.3 5670.6 8793.2 8632.6 9583.3 10887.0 8691.4 14085.0 11538.0 6570.0 True False 7182.064047518706 7503.510555373132 8676.596422625184 6642.487442340475 8252.824214799126 10206.234168950628 9464.917762527182 11908.48689110102 12147.875124706152 6339.9862997523605 1.1328201210465134 1.1835215725412875 1.3685512889774054 1.0477132170774455 1.301710102294934 1.609819593671564 1.4928924630163445 1.878314294080756 1.9160727721415813 1.0 12.630264007471457 -6.703874811449623 3.263710673639323 1.6350314438505245 1.1932782910258843 0.3561125337396318 0.2486617614503004 0.24543995261843368 5.3086691033052205 0.0862284211279771 0.08307117742818866 1.9775395981658925e-07 6.703874811449623 -0.4417531528246401 EAGELPT(ph)SPLHLLSPGTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EAGELPTSPLHLLSPGTPR 19 0 H7C228;Q969R5-2;Q969R5-3;Q969R5 H7C228 L3MBTL2 Lethal(3)malignant brain tumor-like protein 2 1 EAGELPT(0.5)S(0.5)PLHLLSPGTPR;EAGELPT(0.5)S(0.5)PLHLLSPGTPR 103.88 0.0018112000000000002 3666700.0 15586.8 26580.0 28133.9 19468.2 23988.8 14953.3 25806.0 14639.599999999999 18757.3 16437.6 True False 18225.337386667292 29218.686738899676 28804.718874409908 18377.459870756 19288.366845041684 14169.122624219808 23361.468860739333 14255.326011938365 19031.590027174756 19417.60676003 0.9385985416175527 1.5047522127724113 1.4834330116161751 0.9464327966814591 0.9933441892924545 0.7297048909954296 1.2031075275881855 0.7341443355049353 0.9801202724091705 1.0 14.24507777761845 -5.777385110216629 24.646107230249836 0.9342025061677878 1.3285102979598933 0.4323634380470267 0.1926995065352129 164.70537938566295 254572.19012593018 0.052475794850913984 0.07813044562319435 1.6696094331211387e-06 5.777385110216629 0.3943077917921055 EAGELPTS(ph)PLHLLSPGTPR ddPTM_PC-9_AZD4547_30min_R2 3 EAGELPTSPLHLLSPGTPR 19 0 H7C228;Q969R5-2;Q969R5-3;Q969R5 H7C228 L3MBTL2 Lethal(3)malignant brain tumor-like protein 2 1 EAGELPT(0.196)S(0.804)PLHLLSPGTPR;EAGELPT(0.062)S(0.938)PLHLLSPGTPR;EAGELPT(0.071)S(0.929)PLHLLSPGTPR 136.62 5.8106e-05 10820400.0 37441.3 44059.0 59352.1 55023.2 55012.5 63495.0 59500.0 78790.0 64822.0 55532.0 True False 49346.854572580356 58300.21012929576 58565.05237402676 42338.451339965744 47374.963959871515 59524.64761252132 64795.38473322676 66614.81591408224 68248.35858326424 53587.8415826253 0.9208591560175846 1.0879372709834678 1.0928794787102456 0.7900756979488622 0.8840618050799013 1.1107864368961804 1.209143395583883 1.2430957087788483 1.2735791658642266 1.0 15.70961808772865 -6.956473186364816 4.553719978912508 1.1977308191225866 0.9617548074120327 0.49365520137542573 0.10852054579380571 0.17714047716575737 8.180399275105035 0.04188637358914531 0.035963657736798826 1.1054187165755658e-07 6.956473186364816 -0.23597601171055393 EAGELPTS(ph)PLHLLSPGTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EAGELPTSPLHLLSPGTPR 19 0 H7C228;Q969R5-2;Q969R5-3;Q969R5 H7C228 L3MBTL2 Lethal(3)malignant brain tumor-like protein 2 1 EAGELPT(0.185)S(0.815)PLHLLSPGTPR;EAGELPT(0.056)S(0.944)PLHLLSPGTPR;EAGELPT(0.23)S(0.77)PLHLLSPGTPR 107.21 0.00011716 7985400.0 44515.0 69919.0 66483.0 52882.0 60754.0 50940.0 68796.0 43397.0 46878.0 45291.0 True False 52050.51028867336 76860.0962414269 68068.20685818153 49919.1929857572 48849.68982623816 48268.61672525507 62279.14484009233 42257.87473292231 47563.50206553704 53501.8997766413 0.9728721878283355 1.436586299968804 1.2722577542545472 0.9330358958122774 0.9130458923921375 0.9021850985996004 1.1640548298302322 0.7898387703864661 0.8890058533267834 1.0 15.707302500029172 -5.763448683642129 24.999728805048072 0.9392759525456991 1.248173549550494 0.46824936389865945 0.1389404426421357 41.567948345191155 517199.66452163865 0.03787728518475378 0.05951070465658692 1.7240557939084117e-06 5.763448683642129 0.3088975970047949 EAGELPTS(ph)PLHLLSPGTPR ddPTM_PC-9_Lapatinib_30min_R1 4 EAGELPTSPLHLLSPGTPR 19 0 H7C228;Q969R5-2;Q969R5-3;Q969R5 H7C228 L3MBTL2 Lethal(3)malignant brain tumor-like protein 2 1 EAGELPT(0.07)S(0.93)PLHLLSPGTPR;EAGELPT(0.081)S(0.919)PLHLLSPGTPR;EAGELPT(0.205)S(0.795)PLHLLSPGTPR;EAGELPT(0.039)S(0.961)PLHLLSPGTPR 119.38 2.8600000000000004e-05 10913700.0 34957.0 31710.2 39282.0 35270.9 41015.7 45672.5 45195.0 44259.0 43718.8 37816.8 True False 34458.50676967133 31636.7769801689 36052.38559290505 37864.83964627321 38603.23716596881 43719.193642797574 47534.97595916664 46315.43471542315 38794.72836462648 44353.383492281435 0.7769081873013802 0.7132889193374495 0.8128440888659382 0.8537080300280274 0.8703560839431045 0.9857014324601814 1.0717328017926497 1.0442367880115202 0.8746734817058027 1.0 15.436756544083547 -6.282042879690367 1.1496471845495362 1.0052517872450437 0.7531261138698994 0.7607488767939292 0.055535852345040986 0.2323927655477188 0.6359866513914889 0.024491830144779084 0.03551933688858942 5.223446132090244e-07 6.282042879690367 -0.25212567337514435 EAGEQGDIEPR ddPTM_PC-9_AZD4547_30min_R2 1 EAGEQGDIEPR 11 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 0 158.56 0.0045739 11966000.0 39937.0 42489.0 62681.0 68708.0 73768.0 70185.0 45181.0 65574.0 57075.0 64153.0 False True 52636.13525879555 56222.738332319124 61849.80898496217 52868.43212801807 63526.586528367225 65796.32085494617 49202.02147280536 55441.045040614685 60091.86797907816 61907.02299665347 0.8502449756248321 0.9081802937827971 0.9990758074137341 0.8539973264564183 1.0261612245803082 1.0628248245518597 0.7947728559886508 0.8955534018105132 0.9706793360476496 1.0 15.917815463750077 -4.90148296011942 3.805662965714869 0.944917561741324 0.8507255408969175 0.1345627262451562 0.07779123027155341 0.5276242168877733 13.339338996512055 0.020206636292847555 0.11107590779649522 1.2546339634281978e-05 4.90148296011942 -0.09419202084440648 EAGEQGDIEPR ddPTM_PC-9_Lapatinib_30min_R1 1 EAGEQGDIEPR 11 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 0 169.82 0.010915000000000001 16480000.0 59262.0 53041.0 54009.0 52352.0 46968.0 49408.0 49588.0 43571.0 68466.0 46629.0 False True 58416.9130126802 52918.18682332932 49568.588500769 56202.14072115245 44205.43458264084 47294.93501567336 52155.424004052526 45595.4677237557 60754.63810105754 54688.760520763004 1.0681703599865235 0.9676245414857871 0.9063761553335975 1.027672600109759 0.8083093155102301 0.8648017355909443 0.9536771999842879 0.833726478522859 1.11091634775653 1.0 15.738956744430386 -4.775197068153333 2.4801189965110924 0.9284908467442697 1.1011937108759136 0.15755277762702913 0.08770273498445141 0.9184028206270595 7.0127967173694605 0.02201395205399585 0.34491256000288845 1.6780424064257473e-05 4.775197068153333 0.17270286413164382 EAGFPPGVVNIVPGYGPTAGAAISSHMDIDK ddPTM_PC-9_Lapatinib_30min_R1 2 EAGFPPGVVNIVPGYGPTAGAAISSHMDIDK 31 0 P00352 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ; 103.64 3.4847e-14 7757500.0 18863.8 22574.9 23222.9 29911.4 32337.0 28883.0 32959.0 23132.6 26904.4 24831.4 False True 18594.798752802755 22522.629206047717 21313.602804986363 32111.18413750531 30435.001236988108 27647.741419561513 34665.45575037444 24207.425045708183 23874.143156108057 29123.474404239325 0.6384814701262438 0.7733496660951015 0.7318358554734758 1.1025876820806477 1.0450333231037117 0.9493284020926089 1.1902925890369869 0.8311997637955058 0.8197560093528142 1.0 14.829894857570967 -5.744255010169496 24.134966882506944 0.992935281628467 0.7204347850265496 0.5693692537891903 0.11019754840312984 125.02622849536164 175593.50158439117 0.03123177009936977 0.05390279876891314 1.8019593509523672e-06 5.744255010169496 -0.27250049660191744 EAGGGGVGGPGAK ddPTM_PC-9_Lapatinib_30min_R1 2 EAGGGGVGGPGAK 13 0 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 ; 140.07 0.00032812 10285200.0 44853.0 42748.0 41318.0 42389.0 40452.0 42563.0 43208.0 42559.0 41888.0 41174.0 False True 44213.38799496717 42649.01963242927 37920.993532092325 45506.42846555873 38072.69289169194 40742.679709199016 45445.09882163231 44536.446509268026 37170.13233980516 48290.871039093625 0.9155641023574507 0.8831694006493065 0.7852621565138799 0.9423401874180161 0.7884035237399298 0.8436932039642853 0.9410701824956205 0.9222539488511975 0.7697134373433495 1.0 15.559462865682661 -7.238029038589634 24.09399224026158 0.9017805684202709 0.8579305895694954 0.09769564586882129 0.07103001934807558 1353.6018427088668 1393132.1609744693 0.026422397955630575 0.020450989948362048 5.780573949858121e-08 7.238029038589634 -0.04384997885077546 EAGITEK ddPTM_PC-9_Lapatinib_30min_R1 2 EAGITEK 7 0 P60174;P60174-3;P60174-4;U3KPZ0;U3KQF3 P60174 TPI1 Triosephosphate isomerase 0 ; 123.69 0.021516 25920000.0 107271.0 99577.0 92270.0 112699.0 110417.0 101178.0 108337.0 170772.0 143119.0 109090.0 False True 105741.2958689078 99346.43557449253 84683.91677250012 120987.26041284311 103922.48914817449 96850.85279743763 113946.1597629879 178706.69055383606 126999.43111011683 127946.061146712 0.8264521386684764 0.7764712307991637 0.6618720108577282 0.9456114500790341 0.812236720824173 0.7569662710162026 0.8905796610051885 1.396734600129021 0.9926013350617359 1.0 16.965176208749895 -7.565113502931386 10.559832988444333 1.1461094244270116 0.7992474157700906 0.5941718242700869 0.12297962040856666 0.31553238979591247 76.77010473325149 0.0546830848160068 0.03157006862928069 2.7219898226388162e-08 7.565113502931386 -0.34686200865692096 EAGS(ph)PAQEFK ddPTM_PC-9_AZD4547_30min_R2 4 EAGSPAQEFK 10 0 Q5JSZ5;Q5JSZ5-5;Q5JT00 Q5JSZ5 PRRC2B Protein PRRC2B 1 EAGS(1)PAQEFK;EAGS(1)PAQEFK;EAGS(1)PAQEFK;EAGS(1)PAQEFK 122.52 0.0005319 166361400.0 101918.0 104923.0 127851.0 133035.0 128875.0 136045.0 135941.0 147962.0 122890.0 125772.0 True False 134325.80397390728 138837.3078689053 126155.6122036405 102365.8361202609 110982.93079442742 127538.08464360157 148039.48564738804 125097.872728512 129385.71451509265 121368.76056201739 1.1067576479473815 1.1439295188151961 1.0394405580106185 0.8434282071122715 0.914427487604745 1.0508312357563523 1.2197495052422684 1.0307254696284807 1.0660545095455494 1.0 16.889037604580864 -9.588674528746736 15.75316899309883 1.0000037806792492 1.0437813059164271 0.01787049734909285 0.10127653230987943 0.0 0.0 0.10952426568564401 0.02656353623471307 2.5782526408060775e-10 9.588674528746736 0.04377752523717793 EAGS(ph)PAQEFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 EAGSPAQEFK 10 0 Q5JSZ5;Q5JSZ5-5;Q5JT00 Q5JSZ5 PRRC2B Protein PRRC2B 1 EAGS(1)PAQEFK;EAGS(1)PAQEFK;EAGS(1)PAQEFK;EAGS(1)PAQEFK;EAGS(1)PAQEFK 129.37 0.00024865 159599700.0 203522.0 236341.0 230729.0 238090.0 281357.0 225064.0 246330.0 204213.0 204174.0 180655.0 True False 237974.25485727045 259803.37255674464 236230.45440460506 224750.58919819508 226227.11558812368 213261.24763747177 222995.83912523877 198852.62513155857 207159.6584907407 213406.32143580678 1.1151228007500882 1.2174117936562354 1.1069515317786116 1.053158068074383 1.0600769183689502 0.9993201991517451 1.0449354903121582 0.931802880972174 0.9707287820574467 1.0 17.703243386161546 -6.037878781777612 0.6980597728385717 0.9743966813150473 1.1847563171808277 0.756369454563814 0.038541477785250876 0.42003011921019157 0.40512584652454736 0.02211220440653948 0.05457591301151776 9.164762569457465e-07 6.037878781777612 0.21035963586578044 EAGS(ph)PAQEFK ddPTM_PC-9_Lapatinib_30min_R1 4 EAGSPAQEFK 10 0 Q5JSZ5;Q5JSZ5-5;Q5JT00 Q5JSZ5 PRRC2B Protein PRRC2B 1 EAGS(1)PAQEFK;EAGS(1)PAQEFK;EAGS(1)PAQEFK;EAGS(1)PAQEFK 147.73 0.0001484 101934500.0 153804.0 157080.0 168342.0 130670.0 157361.0 151068.0 142509.0 138957.0 161770.0 127778.0 True False 151610.7267558009 156716.29091096637 154501.57057891178 140279.90770234176 148105.33536362924 144607.17379670782 149887.41871810766 145413.44950746835 143549.75908638 149864.25704651716 1.0116536774258431 1.0457216016646476 1.030943425896111 0.9360464627586252 0.9882632342257437 0.964921033517835 1.0001545510053362 0.9703010736064485 0.9578652169331 1.0 17.193296812822176 -5.733391284311866 24.972565158933435 0.9740122794803924 1.031067835411593 0.6204831391132598 0.019879846848652245 128.80938124699776 114684.16772253314 0.005149885044545298 0.008917488205709586 1.8476032422294733e-06 5.733391284311866 0.0570555559312006 EAGT(ph)PSLDSEAK ddPTM_PC-9_AZD4547_30min_R2 4 EAGTPSLDSEAK 12 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 EAGT(0.962)PS(0.037)LDS(0.001)EAK;EAGT(0.939)PS(0.06)LDS(0.001)EAK;EAGT(1)PSLDSEAK;EAGT(0.973)PS(0.027)LDSEAK 148.96 0.00019873 42068700.0 209837.0 202972.0 211803.0 251113.0 278124.0 248489.0 243784.0 314135.0 277983.0 268341.0 True False 276560.8011192595 268578.7296662072 208994.35383037815 193222.77750717546 239511.2833696943 232950.9435481194 265480.3037278141 265592.65385417227 292676.6138664578 258946.46326664317 1.0680230872065568 1.0371979067721249 0.8070948380367405 0.7461881312053661 0.9249451811321477 0.8996104469217809 1.0252323989242629 1.0256662728800638 1.1302591669888222 1.0 17.98229432847414 -7.370627786189848 2.776960678890833 1.0566522819489892 0.9065548634369288 0.317166579018748 0.09434111843956917 0.369662007359277 5.519911551401649 0.05051652119684698 0.0314684826880169 4.25963330298142e-08 7.370627786189848 -0.15009741851206038 EAGT(ph)PSLDSEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EAGTPSLDSEAK 12 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 EAGT(0.883)PS(0.093)LDS(0.024)EAK;EAGT(0.995)PS(0.003)LDS(0.002)EAK;EAGT(0.997)PS(0.003)LDSEAK;EAGT(0.997)PS(0.001)LDS(0.001)EAK 168.76 0.00017508 40093100.0 214131.0 182569.0 183106.0 187649.0 229181.0 180774.0 185462.0 170782.0 155200.0 155247.0 True False 250379.14901996867 200693.24376351287 187471.9414733717 177135.63489626645 184274.62823957377 171293.89320556083 167893.69673139692 166299.1534584863 157469.50639044688 183392.05216542393 1.3652671752324403 1.094339920371701 1.0222468163683975 0.9658850141252902 1.0048125099410183 0.9340311708331271 0.9154905828740761 0.906795858898403 0.8586495681307154 1.0 17.484571591286965 -1.5228787452870904 0.6628361887671368 0.9248387259697309 43.172458050501675 0.9131171536918674 0.039951187770832314 61.3065300518061 0.37676558310326463 0.016593694483533636 3811.305828786643 0.02999999999953353 1.5228787452870904 42.24761932453195 EAGT(ph)PSLDSEAK ddPTM_PC-9_Lapatinib_30min_R1 3 EAGTPSLDSEAK 12 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 EAGT(0.982)PS(0.018)LDSEAK;EAGT(0.963)PS(0.036)LDS(0.001)EAK;EAGT(1)PSLDSEAK 154.23 0.00015359 28848800.0 224014.0 243266.0 233451.0 213213.0 218330.0 183614.0 183741.0 158498.0 189485.0 183883.0 True False 220819.51928086346 242702.73252321893 214257.55992691976 228893.39527771738 205488.25865329517 175761.25724513942 193254.20992838236 165862.39570539675 168143.20393449135 215666.93154130448 1.0238914130355314 1.1253590468816799 0.9934650546362747 1.0613281954812797 0.9528037385459815 0.814966188784847 0.8960771526133127 0.7690673508452585 0.7796429556113409 1.0 17.71844545780249 -6.522134658946799 2.7512425218157657 0.8397479193860709 1.0526384323138214 0.641256728608907 0.06964503563343433 0.15995999995732574 2.449542062719896 0.02337499421362313 0.024975309204673796 3.0051443720232286e-07 6.522134658946799 0.21289051292775052 EAGTPS(ph)LDSEAK ddPTM_PC-9_Lapatinib_30min_R1 1 EAGTPSLDSEAK 12 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 EAGT(0.307)PS(0.692)LDSEAK 159.66 0.00017816 12244000.0 127870.0 132710.0 118920.0 99269.0 123260.0 111410.0 90954.0 86835.0 129320.0 92197.0 True False 126046.5503515138 132402.71814867825 109142.85664447492 106569.57341167628 116010.08913848402 106645.25400939467 95663.15307866 90869.67110675287 114754.61980002867 108133.12860521968 1.1656608106817452 1.2244417585665515 1.009337823221056 0.985540460969628 1.0728450257092081 0.986240344517756 0.8846794161289278 0.8403499674785745 1.061234621435797 1.0 16.722449061823426 -5.245087216210249 0.7690775137009522 0.9484885487644313 1.2776512992032445 0.5530537473440368 0.0734911260286923 1.1591193830852453 0.8095126721712529 0.032606521403919564 0.29338590353728955 5.6873870370652235e-06 5.245087216210249 0.32916275043881316 EAHAQSIGMNR ddPTM_PC-9_AZD4547_30min_R2 1 EAHAQSIGMNR 11 0 P25205;J3KQ69;A0A499FHX9;P25205-2 P25205 MCM3 DNA replication licensing factor MCM3 0 67.87899999999999 0.026194 549230.0 3441.7 2978.4 3671.8 6015.2 6617.0 4310.4 3869.1 6176.1 3770.5 4752.6 False True 4536.089008192819 3941.109554213546 3623.109532888499 4628.488573913583 5698.34376773406 4040.8700065991334 4213.442404560129 5221.725657659141 3969.800932371686 4586.212920578856 0.9890707402264022 0.8593385484850347 0.7900002890470255 1.0092179874913858 1.2424943774775363 0.8810907990048374 0.918719317555872 1.1385702644176565 0.8655945550540709 1.0 12.163087620028355 -5.829803356458342 10.741029845622428 1.0146743111934908 0.8775609464515886 0.20021585395524655 0.11713308540032964 0.7015143592605309 106.4264400336608 0.03326121556561441 0.04939231787123372 1.4797782630627398e-06 5.829803356458342 -0.13711336474190228 EAHAQSIGMNR ddPTM_PC-9_Lapatinib_30min_R1 1 EAHAQSIGMNR 11 0 P25205;J3KQ69;A0A499FHX9;P25205-2 P25205 MCM3 DNA replication licensing factor MCM3 0 62.799 0.036328 501250.0 2819.9 2783.0 4586.4 3665.9 5592.4 5147.6 3419.9 3123.1 4907.4 4387.6 False True 2779.6877088936726 2776.5561344870093 4209.323896015979 3935.502515083908 5263.46602708143 4927.4491476416815 3596.9656883007865 3268.2106274370867 4354.676934787046 5145.990813890493 0.5401656958637596 0.5395571494205342 0.817981230097383 0.764770606364253 1.022828492595408 0.9575316641337747 0.6989840865225707 0.635098418484397 0.846227110050903 1.0 12.329233166380815 -5.270825729806833 5.02641017739618 0.8337076539130893 0.5358533074378243 0.5088567457927637 0.11888771910029032 0.15085965178005944 12.073261039755092 0.03378850334559287 0.081296559183635 5.3601170082487605e-06 5.270825729806833 -0.297854346475265 EAHQLFLEPEVLDPESVELK ddPTM_PC-9_Lapatinib_30min_R1 1 EAHQLFLEPEVLDPESVELK 20 0 P39748-2;I3L3E9;P39748 P39748-2 FEN1 Flap endonuclease 1 0 125.92 1.3757e-05 2405800.0 13551.0 9920.5 13505.0 13083.0 15336.0 12761.0 14569.0 11435.0 13426.0 12664.0 False True 13357.760255050947 9897.529691763706 12394.671030807553 14045.167463608597 14433.966631736084 12215.241777343908 15323.311533335514 11966.311845519873 11913.822497952253 14852.955526280693 0.8993334849361018 0.6663676918880623 0.8344918968400954 0.9456143215912279 0.9717908739574926 0.8224115231295457 1.0316675025534532 0.8056519003471586 0.8021179674895031 1.0 13.858462414875174 -5.53543042273406 7.882780692334982 0.9059690158836874 0.7747295740091559 0.2425902043065017 0.09254811910287833 0.181600159906533 70.56239155578562 0.02436972931510981 0.04373980544589378 2.914537028280479e-06 5.53543042273406 -0.13123944187453151 EAIAELER ddPTM_PC-9_Lapatinib_30min_R1 1 EAIAELER 8 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 95.815 0.029077 3813900.0 24812.0 27205.0 23655.0 23402.0 32466.0 38735.0 49048.0 43064.0 45082.0 34354.0 False True 24458.176330036455 27142.00849397022 21710.177210940594 25123.061146783486 30556.413710611865 37078.39434569519 51587.46544629281 45064.91065286119 40004.3904254941 40292.04312617239 0.6070224896128245 0.6736319726695532 0.5388204599840303 0.6235241302634358 0.758373399306808 0.9202411064037176 1.2803387826412624 1.1184568256254173 0.9928608062942471 1.0 15.298207342972471 -6.774413106690094 2.1526411399996226 1.1071929661679862 0.6148680362205801 0.8662929069186732 0.08589107999318332 0.10370172791926333 0.9879304309812594 0.0343983031514904 0.031407894234450756 1.6810742401193137e-07 6.774413106690094 -0.4923249299474062 EAIDSYIK ddPTM_PC-9_Lapatinib_30min_R1 2 EAIDSYIK 8 0 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 ; 92.439 0.036739 15487000.0 65612.0 74882.0 88511.0 79703.0 75177.0 85338.0 81310.0 64387.0 94369.0 78288.0 False True 64676.36084823278 74708.61532973622 81233.96724234027 85564.62450141372 70755.23666366865 81688.29267259421 85519.8339471144 67378.65507629974 83740.16947037519 91819.97648779723 0.7043822414486045 0.8136422833833431 0.8847090834654718 0.9318737356983005 0.7705865256137583 0.8896570854976258 0.9313859273148462 0.733812593442063 0.9120038217555431 1.0 16.486520442171035 EAIEGTYIDKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAIEGTYIDKK 11 1 P62280;M0QZC5 P62280 RPS11 40S ribosomal protein S11 0 70.41199999999999 0.020431 6886800.0 22182.0 13433.0 27248.0 37595.0 24993.0 30283.0 27309.0 32546.0 21020.0 20401.0 False True 25936.974485529674 14766.539464395755 27897.695658615456 35488.67403463451 20095.801063751693 28694.90616982529 24722.093819961658 31691.701985337455 21327.377734066922 24099.53980577287 1.076243558780183 0.6127311800725148 1.1576028373758724 1.472587207915624 0.8338665893917978 1.1906827433672253 1.0258326100500748 1.3150334919568023 0.8849703316309012 1.0 14.556717977196875 -5.292416092985384 24.831877954629636 1.1242761020334981 0.8444872715927715 0.2027620371904626 0.20913919624099014 760.0186774476265 609252.8894690406 0.05189497647755477 0.10804613539594882 5.100161247229735e-06 5.292416092985384 -0.27978883044072667 EAIEGTYIDKK ddPTM_PC-9_Lapatinib_30min_R1 2 EAIEGTYIDKK 11 1 P62280;M0QZC5 P62280 RPS11 40S ribosomal protein S11 0 ; 126.66 0.00025285 36894000.0 120904.0 100997.0 112596.0 94580.0 95521.0 88890.0 103084.0 94503.0 93562.0 87478.0 False True 119179.88678892162 100763.14765173724 103338.79151312904 101535.72870963073 89902.6425815115 85088.38191271068 108421.18512611424 98893.9543801629 83024.06230846191 102598.45574289195 1.161614820866136 0.9821117376683142 1.00721585685551 0.9896418808103274 0.8762572684992872 0.8293339436408197 1.056752602571464 0.9638932054492867 0.8092135666887349 1.0 16.646649490870686 -1.5228787452870405 0.7506063790917069 0.9290887690374667 40.77945762781264 0.44597375033687003 0.0749767503349629 366.0191780998854 1.5751632680452705 0.028457804856136894 24665.199710396828 0.02999999999953698 1.5228787452870405 39.85036885877517 EAILAIHK ddPTM_PC-9_AZD4547_30min_R2 2 EAILAIHK 8 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ; 93.429 0.0060695 29582000.0 319130.0 331150.0 436200.0 534510.0 500510.0 453590.0 362610.0 434040.0 362550.0 409410.0 False True 420606.70168363745 438187.7615088018 430415.7029919827 411286.9775971791 431022.8259314753 425226.94559514243 394881.58753135067 366969.091246964 381713.65283950546 395076.68051470636 1.064620420359082 1.1091207938112932 1.0894485152381979 1.0410307615760919 1.0909852370176298 1.0763149701499877 0.999506189575397 0.9288553573166511 0.9661761163483719 1.0 18.591773167883098 -7.377391378404211 3.218333591019342 0.9608044339478609 1.0797921857148118 0.8298172553107485 0.02358153540098868 0.09543144974494583 1.8642566781677175 0.010867399649830313 0.0068903564252782885 4.193808751150887e-08 7.377391378404211 0.11898775176695098 EAILAIHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EAILAIHK 8 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ; 103.56 0.0033016999999999994 39123000.0 281960.0 272790.0 295250.0 319180.0 348110.0 303820.0 315070.0 304740.0 293070.0 247137.0 False True 329690.2590361529 299870.78839369526 302289.8797418603 301297.3793955218 279900.34442854364 287887.1443554574 285224.2886907368 296740.8978987203 297355.5943160319 291940.9817645839 1.129304481485951 1.027162361999268 1.035448596201617 1.0320489352826894 0.9587566046285697 0.9861141886122878 0.9769929763432004 1.0164413920413782 1.0185469423262208 1.0 18.155317220523663 -1.5228787464947031 0.7825701523962113 0.9960043849991951 29.690337037314347 0.7574619097872366 0.021752518095354077 229.55514109730692 0.862076560532639 0.008390801466499708 11656.591642137519 0.0299999999161146 1.5228787464947031 28.69433265231515 EAILAIHK ddPTM_PC-9_Lapatinib_30min_R1 2 EAILAIHK 8 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ; 93.429 0.0060695 45272000.0 321720.0 329190.0 327490.0 309610.0 321130.0 311820.0 315800.0 264460.0 301720.0 285890.0 False True 317132.2138037778 328427.7807803735 300565.03634795814 332379.7522286824 302241.7647658712 298484.1854879228 332150.57877873245 276747.7770586954 267737.1163475459 335305.7055755211 0.9458002310442342 0.9794875998804068 0.896391058517976 0.9912737740569711 0.9013916546606366 0.8901852265698922 0.9905902979152318 0.8253595821868988 0.7984866105633365 1.0 18.355117506734857 -7.7687545448994895 24.99806899593281 0.8589423204632574 0.940157264268948 0.19103902161816744 0.06109872473846814 226.4487663756202 773826.8253485587 0.03090492097610787 0.015321589579511406 1.7031208083890182e-08 7.7687545448994895 0.08121494380569061 EAKPDELMDSKLRCVFEMPNENDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAKPDELMDSKLRCVFEMPNENDK 24 3 Q9P0L0;Q9P0L0-2 Q9P0L0 VAPA Vesicle-associated membrane protein-associated protein A 0 52.853 0.024112 0.0 4208.9 2330.1 3123.2 3895.2 5046.8 4897.2 4520.4 4858.6 3313.9 4378.2 False True 4921.383640435751 2561.416928905573 3197.668932801957 3676.964572408785 4057.915768756936 4640.382210972112 4092.1949871381107 4731.066898112225 3362.3595182171425 5171.933002187872 0.9515559537128319 0.49525330815809526 0.618273463992912 0.7109459018230372 0.784603313121095 0.8972239603662887 0.7912312447603242 0.9147579630499567 0.6501166037523631 1.0 12.3364878710946 -6.307431867323806 2.704084026342841 0.8412895209190009 0.6699327779669794 0.21891911171915546 0.13655444425322738 0.4000985934521101 5.788036273018714 0.04318666030982699 0.05264637401043746 4.926836301277656e-07 6.307431867323806 -0.17135674295202152 EALAEAALES(ph)PRPALVR ddPTM_PC-9_AZD4547_30min_R2 4 EALAEAALESPRPALVR 17 1 J3QRP6;O14745;O14745-2 J3QRP6 SLC9A3R1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 1 EALAEAALES(1)PRPALVR;EALAEAALES(1)PRPALVR;EALAEAALES(1)PRPALVR;EALAEAALES(1)PRPALVR 147.64 3.751e-05 454118000.0 84453.0 81781.0 106052.0 158546.0 119115.0 117359.0 103321.0 133227.0 101036.0 104609.0 True False 111307.29726847411 108215.10893538078 104645.6811868543 121995.66921128199 102577.93832456422 110020.52317753974 112516.36884070112 112639.8284018968 106376.55669091795 100946.67075050146 1.1026346529404605 1.072002752848025 1.036643213776661 1.2085160243947517 1.0161596966193622 1.0898875847967795 1.1146119827844068 1.1158350004458888 1.0537896485346894 1.0 16.623233805403927 -8.551156257067642 4.440877431776512 1.000062702745478 1.0933397878496458 0.26725519243821216 0.04895329366409658 0.25666451572081206 18.013552034942517 0.04546510650828964 0.011866682189531727 2.8108893039744765e-09 8.551156257067642 0.09327708510416777 EALAEAALES(ph)PRPALVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 EALAEAALESPRPALVR 17 1 J3QRP6;O14745;O14745-2 J3QRP6 SLC9A3R1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 1 EALAEAALES(1)PRPALVR;EALAEAALES(1)PRPALVR;EALAEAALES(1)PRPALVR;EALAEAALES(1)PRPALVR;EALAEAALES(1)PRPALVR;EALAEAALES(1)PRPALVR 120.74 3.8368e-05 425358200.0 66131.2 66874.4 83488.3 96723.5 92344.1 102941.5 104375.0 91925.9 92802.1 91114.4 True False 77325.90600926235 73513.24847448709 85478.97770314079 91304.39587681783 74249.93650266848 97543.06652184615 94487.8443904388 89512.94252854223 94159.15514817563 107632.71945880656 0.7184237878413609 0.6830009391579318 0.7941727955304102 0.8482959116513084 0.6898454008781743 0.9062584966012872 0.8778728704945655 0.8316517781825705 0.8748190663733293 1.0 16.71575718639631 -2.0516616629974327 0.08343631297952463 1.1486909161979066 1.653051722793908e-12 0.6737657562977435 0.055307889315650026 97.76898938311348 0.6597152933063821 1.440158276648869 12.973395164684408 0.008878474199827856 2.0516616629974327 -1.1486909161962535 EALAEAALES(ph)PRPALVR ddPTM_PC-9_Lapatinib_30min_R1 5 EALAEAALESPRPALVR 17 1 J3QRP6;O14745;O14745-2 J3QRP6 SLC9A3R1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 1 EALAEAALES(1)PRPALVR;EALAEAALES(1)PRPALVR;EALAEAALES(1)PRPALVR;EALAEAALES(1)PRPALVR;EALAEAALES(1)PRPALVR 141.64 4.7588999999999994e-05 444518600.0 111711.0 96432.7 123902.0 91788.8 112623.4 105409.0 108344.1 113751.0 130048.0 87325.9 True False 110117.98065471159 96209.41600795719 113715.25583555136 98539.25455046083 105999.11303812357 100900.90279038047 113953.62736624716 119036.2867284416 115400.62477384898 102420.06546055226 1.0751602252892938 0.9393610087567544 1.1102829833608094 0.9621088807877578 1.0349447890066992 0.9851673335362502 1.1126103742839057 1.1622359953898798 1.1267384399231444 1.0 16.644138860717725 -7.274529277225642 23.347202080556723 1.1139158964252673 1.016716971098276 0.29162110358164317 0.06159677056591444 344.6232614580051 614666.6790665931 0.023884786546981073 0.01623318526336521 5.3146017081329497e-08 7.274529277225642 -0.09719892532699137 EALEAYRR ddPTM_PC-9_AZD4547_30min_R2 2 EALEAYRR 8 1 Q9NRF9 Q9NRF9 POLE3 DNA polymerase epsilon subunit 3 0 ; 91.318 0.0055778 3845200.0 29302.0 27146.0 46342.0 68024.0 52808.0 38737.0 31452.0 47778.0 30951.0 40125.0 False True 38619.42648053756 35920.41363103709 45727.474800675125 52342.117760323534 45476.52073243166 36314.76926633971 34251.167069402494 40395.007929217216 32587.006672281157 38720.23596309946 0.9973964651801716 0.9276909796022262 1.1809709745636259 1.3518026545655812 1.1744897622982196 0.9378757221662551 0.8845805356672928 1.0432531446273678 0.8416014484864375 1.0 15.240800124046155 -6.769081594679903 24.730239921108787 0.9406103423686721 1.1309731754938472 0.3801773012312456 0.11804142961265678 183.47523115517242 593722.239028236 0.04593834197082575 0.0412869447546907 1.7018387391179317e-07 6.769081594679903 0.1903628331251751 EALEAYRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EALEAYRR 8 1 Q9NRF9 Q9NRF9 POLE3 DNA polymerase epsilon subunit 3 0 ; 95.815 0.0047114 1451100.0 24262.0 17329.1 20910.0 25121.0 30174.0 30999.0 28011.0 29945.0 29032.0 22152.0 False True 28369.07740365705 19049.41852396788 21408.57370161661 23713.55181338087 24261.621305871384 29373.357869379313 25357.595297921773 29158.975479350156 29456.538076852095 26167.982244864477 1.0841140573314376 0.7279666558053542 0.8181209197288449 0.9062048266268105 0.9271491045371976 1.1224922729815707 0.969031355212657 1.1142997272964241 1.1256709745984717 1.0 14.675515065205728 -6.598059394323011 3.8751099465228673 1.0671176403294564 0.8719470500996542 0.4474357643245459 0.0966015169161531 0.19985072639997034 5.923901399319739 0.03247097629474729 0.03279377505668908 2.5231356836296583e-07 6.598059394323011 -0.1951705902298022 EALEAYRR ddPTM_PC-9_Lapatinib_30min_R1 1 EALEAYRR 8 1 Q9NRF9 Q9NRF9 POLE3 DNA polymerase epsilon subunit 3 0 79.71300000000001 0.012861000000000001 3243900.0 23571.0 18775.0 21405.0 19654.0 19739.0 21208.0 15939.0 15749.0 20549.0 14353.0 False True 23234.873217608005 18731.52764103257 19645.16352568944 21099.42072382201 18577.990828367143 20300.983278262658 16764.24342987403 16480.75603455115 18234.55522943698 16833.896925829675 1.3802432865058576 1.112726763361085 1.167000345329797 1.253388969695269 1.1036060699564672 1.2059586302392726 0.9958623070901207 0.9790220355491976 1.0832046382236165 1.0 14.039081568385106 -7.2601725239575945 24.961829717744735 1.012774075233079 1.1957042931091968 0.5869778063473825 0.07760633698149136 81.06479575647444 1597301.1985509046 0.0298338676631588 0.02179453811382584 5.4932261150021895e-08 7.2601725239575945 0.18293021787611785 EALGIPAAASFK ddPTM_PC-9_Lapatinib_30min_R1 2 EALGIPAAASFK 12 0 P31939-2;P31939 P31939-2 ATIC Bifunctional purine biosynthesis protein PURH;Phosphoribosylaminoimidazolecarboxamide formyltransferase;IMP cyclohydrolase 0 ; 127.87 0.0010207 6989700.0 58169.0 63836.0 67751.0 57842.0 55432.0 54696.0 57100.0 48282.0 55094.0 57025.0 False True 57339.49939311186 63688.19166407217 62180.774306423045 62095.89363525553 52171.59874350507 52356.779582603434 60056.35860755424 50525.35798210671 48888.73355446013 66881.69526896373 0.8573272427159917 0.9522514554685115 0.9297128916419358 0.9284437750200236 0.7800579595612488 0.782826741637625 0.8979491079889423 0.7554437395601254 0.7309733008090603 1.0 16.029323795824855 -6.252709264816486 24.564806812246754 0.8138986065460315 0.9203693254216669 0.2501104791086747 0.07697124107411953 627.2880044752484 1765062.3693953103 0.022013624579122634 0.02796642424358187 5.588441835879779e-07 6.252709264816486 0.10647071887563542 EALGLGPPAAQLT(ph)PPPAPVGLR ddPTM_PC-9_AZD4547_30min_R2 5 EALGLGPPAAQLTPPPAPVGLR 22 0 A0A087WZ13;Q8IY67-2;E9PAU2;Q8IY67 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 EALGLGPPAAQLT(1)PPPAPVGLR;EALGLGPPAAQLT(1)PPPAPVGLR;EALGLGPPAAQLT(1)PPPAPVGLR;EALGLGPPAAQLT(1)PPPAPVGLR;EALGLGPPAAQLT(1)PPPAPVGLR 156.08 1.5823e-05 159362000.0 97184.3 123074.6 125899.8 135324.3 120997.3 145302.5 101219.3 153336.0 122611.9 113535.5 True False 128086.88584098394 162856.05759502074 124230.28639053195 104127.37337459339 104198.91346042725 136216.71170514796 110227.62161223346 129641.44451074641 129092.91471684488 109560.65670251689 1.1690956379420958 1.4864465264863598 1.1338950507374794 0.9504084450435876 0.9510614174516311 1.2432995183207833 1.0060876315439358 1.1832846608683043 1.1782780297434936 1.0 16.741370293079278 -5.453094947022489 7.841437540225531 1.0771622745510026 1.3253938591219279 0.41406905841133546 0.11935567310891519 0.2849260649719297 28.922290582371577 0.03097756200452028 0.06455607360592705 3.5229384287500983e-06 5.453094947022489 0.2482315845709253 EALGLGPPAAQLT(ph)PPPAPVGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 EALGLGPPAAQLTPPPAPVGLR 22 0 A0A087WZ13;Q8IY67-2;E9PAU2;Q8IY67 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 EALGLGPPAAQLT(1)PPPAPVGLR;EALGLGPPAAQLT(1)PPPAPVGLR;EALGLGPPAAQLT(1)PPPAPVGLR;EALGLGPPAAQLT(1)PPPAPVGLR;EALGLGPPAAQLT(1)PPPAPVGLR;EALGLGPPAAQLT(1)PPPAPVGLR;EALGLGPPAAQLT(1)PPPAPVGLR;EALGLGPPAAQLT(1)PPPAPVGLR 178.84 1.0492e-12 134070500.0 140369.9 176101.69999999998 182320.0 161879.2 198815.0 187773.4 224990.7 156700.8 176454.3 168570.4 True False 164131.75163810048 193583.9129604094 186667.2002524505 152809.63324344778 159858.6279554194 177926.23234782138 203677.9521043924 152587.57003822149 179034.610318761 199130.8791174479 0.8242405816995121 0.9721441185735593 0.9374096126113806 0.7673829087718749 0.8027817115251842 0.8935140202081869 1.022834595051743 0.7662677466924903 0.8990800980352521 1.0 17.603357430780633 -6.990501345325558 24.829060422663893 0.9105116964564742 0.864255458136375 0.09585515062241512 0.0856256880574594 643.1396851688356 1681128.12316974 0.03163417354939838 0.027863751918908726 1.0221123943704425e-07 6.990501345325558 -0.046256238320099174 EALGLGPPAAQLT(ph)PPPAPVGLR ddPTM_PC-9_Lapatinib_30min_R1 5 EALGLGPPAAQLTPPPAPVGLR 22 0 A0A087WZ13;Q8IY67-2;E9PAU2;Q8IY67 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 EALGLGPPAAQLT(1)PPPAPVGLR;EALGLGPPAAQLT(1)PPPAPVGLR;EALGLGPPAAQLT(1)PPPAPVGLR;EALGLGPPAAQLT(1)PPPAPVGLR;EALGLGPPAAQLT(1)PPPAPVGLR 262.17 2.5898999999999996e-74 135749100.0 68678.2 91229.7 91157.20000000001 81616.70000000001 115000.1 126237.8 136379.6 136419.09999999998 125052.9 102143.70000000001 True False 67698.83627396045 91018.46323478597 83662.60689296803 87619.06438332963 108236.0202168957 120838.90356868476 143440.6683774921 142757.6294084089 110968.12553658364 119799.10244707503 0.5651030340888281 0.7597591415594804 0.6983575434542891 0.7313833125088569 0.9034793917985514 1.008679540166581 1.1973434311902418 1.1916418945749323 0.9262851162479055 1.0 16.870257573715392 -6.490668962868539 1.624238265083874 1.0943852480653584 0.6807477764899983 0.7988392679567445 0.08934966090542826 0.1588065261837715 0.8480643387879799 0.03503153303996321 0.03942778995589273 3.2309559509649567e-07 6.490668962868539 -0.4136374715753601 EALHTAGYEMS(ph)LNGSPR ddPTM_PC-9_AZD4547_30min_R2 1 EALHTAGYEMSLNGSPR 17 0 O94929;A0A0C4DGA7;O94929-2;O94929-3;A0A0A0MRD5;O94929-4 O94929 ABLIM3 Actin-binding LIM protein 3 1 EALHTAGYEMS(0.888)LNGS(0.112)PR 80.016 0.004171899999999999 12389000.0 31337.0 23053.0 51876.0 64007.0 56183.0 54053.0 43215.0 63140.0 39667.0 48204.0 True False 41301.514149908 30504.43142401451 51188.090344823766 49251.17504829211 48382.96023917223 50673.05736514079 47061.051281452055 53383.163812858926 41763.716638214486 46516.39263215571 0.887891597194861 0.6557780966645187 1.100431212489135 1.0587917992214622 1.0401270928676056 1.0893591376669152 1.0117089614752248 1.1476204579104954 0.8978279327994191 1.0 15.505451599028389 -5.269740134711232 24.999785158678186 1.049471692629493 0.7718348426438446 0.6341759545448971 0.08234252401224415 295.2014514779288 889074.2425831121 0.0196239096464466 0.04196572314119383 5.37353231915634e-06 5.269740134711232 -0.2776368499856483 EALHTAGYEMSLNGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 EALHTAGYEMSLNGSPR 17 0 O94929;A0A0C4DGA7;O94929-2;O94929-3;A0A0A0MRD5;O94929-4 O94929 ABLIM3 Actin-binding LIM protein 3 1 EALHTAGYEMS(0.039)LNGS(0.961)PR;EALHTAGYEMS(0.169)LNGS(0.831)PR 122.97 0.00039802 10010000.0 55453.5 63430.4 64578.0 78495.0 64982.0 72159.0 59910.0 73380.0 66665.0 57905.0 True False 73086.55949554595 83933.0363509223 63721.65352548437 60399.19048566074 55960.37097096788 67646.88632289032 65241.87393895156 62040.80710464986 70188.77580070519 55877.7635749103 1.3079721667379434 1.5020829571749201 1.1403758749230983 1.0809163900178105 1.0014783590246383 1.2106226519284762 1.1675820534851513 1.1102951001515535 1.2561128311194738 1.0 15.769986659710696 -5.278754573620457 21.464400923651226 1.1240371621893084 1.405027430274489 0.6221155180565021 0.08854251344649404 69.56841912099358 86239.60412413826 0.022673754824444673 0.04750748316789813 5.2631461071185636e-06 5.278754573620457 0.2809902680851806 EALHTAGYEMSLNGS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EALHTAGYEMSLNGSPR 17 0 O94929;A0A0C4DGA7;O94929-2;O94929-3;A0A0A0MRD5;O94929-4 O94929 ABLIM3 Actin-binding LIM protein 3 1 EALHT(0.001)AGYEMS(0.007)LNGS(0.992)PR;EALHT(0.001)AGY(0.009)EMS(0.035)LNGS(0.956)PR;EALHTAGY(0.002)EMS(0.225)LNGS(0.773)PR 77.13 0.0069374 20849700.0 72645.0 83445.0 85081.0 86406.0 108609.0 89235.0 110848.0 95580.0 96168.0 74322.0 True False 84942.36369584818 91728.86813120682 87109.6537114895 81564.95195203184 87327.84610622992 84555.35951076058 100347.67496997751 93071.1262753812 97574.27506801824 87795.99026737167 0.9674970740368309 1.0447956433073773 0.9921825979319555 0.9290282130611662 0.994667818430932 0.9630890801875786 1.1429642135635267 1.060084019690931 1.1113750727210665 1.0 16.421867431457287 -7.247134648465198 24.981066808211093 1.0836128299152472 0.9833843399930204 0.5348142170748824 0.04408288681292744 586.0206460567575 1023398.7269083958 0.016426327773361716 0.012660961837744074 5.6606375967651817e-08 7.247134648465198 -0.10022848992222677 EALHTAGYEMSLNGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 EALHTAGYEMSLNGSPR 17 0 O94929;A0A0C4DGA7;O94929-2;O94929-3;A0A0A0MRD5;O94929-4 O94929 ABLIM3 Actin-binding LIM protein 3 1 EALHTAGY(0.001)EMS(0.135)LNGS(0.863)PR;EALHTAGY(0.002)EMS(0.168)LNGS(0.83)PR;EALHTAGYEMS(0.041)LNGS(0.959)PR 91.337 0.0012656 14375100.0 65633.3 62103.8 83605.7 71112.8 77473.0 80635.4 74699.4 57207.9 90388.6 66852.6 True False 64697.35710632685 61960.002466746126 76731.96207333475 76342.67253734668 72916.19045777834 77186.81191229819 78566.96942502867 59865.98788170668 80208.08403384525 78407.98283451008 0.8251373746328707 0.7902256916559186 0.9786243606762237 0.9736594384589321 0.9299587595777988 0.984425426110128 1.0020276837226403 0.7635190412698332 1.0229581368409197 1.0 16.258712924316832 -5.258880154281508 24.931292403113815 0.9506824617241757 0.8076815206321806 0.4198007877334904 0.06986317905597321 203.44308021480222 1981860.8097105904 0.017671731541927638 0.0425154737848597 5.509597154981559e-06 5.258880154281508 -0.14300094109199513 EALPWGLEPQDVQS(ph)SDEMRSPEGYLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EALPWGLEPQDVQSSDEMRSPEGYLR 26 1 Q9H5H4 Q9H5H4 ZNF768 Zinc finger protein 768 1 EALPWGLEPQDVQS(0.661)S(0.26)DEMRS(0.078)PEGY(0.002)LR 52.91 0.01621 3924200.0 4506.1 4358.5 5902.0 7207.5 10358.0 5134.4 7081.3 5130.0 5546.2 6059.5 True False 5268.893730468184 4791.183075676981 6042.726063459642 6803.687142030279 8328.424255525151 4865.143025405374 6410.507999827694 4995.342935684297 5627.302682620452 7158.039383024396 0.7360805729797459 0.6693429330717965 0.8441873172408401 0.9504959078830331 1.1635063471816562 0.6796753643104108 0.8955675788862653 0.6978646900897153 0.7861514000559773 1.0 12.80534876604389 -5.347438391124793 5.073487842926615 0.8745053282889138 0.7033877624795615 0.2101596209697929 0.13602147775227208 0.3460589833976429 14.889371163572097 0.037636261786992566 0.08177342980942828 4.4932606139957906e-06 5.347438391124793 -0.17111756580935233 EALPWGLEPQDVQSSDEMRS(ph)PEGYLR ddPTM_PC-9_AZD4547_30min_R2 1 EALPWGLEPQDVQSSDEMRSPEGYLR 26 1 Q9H5H4 Q9H5H4 ZNF768 Zinc finger protein 768 1 EALPWGLEPQDVQS(0.193)S(0.193)DEMRS(0.565)PEGY(0.049)LR 49.871 0.035302 5215200.0 9157.3 8861.6 12194.0 19471.0 13913.0 15804.0 12235.0 14450.0 9116.8 10617.0 True False 12069.130916327427 11725.938901967085 12032.299592581938 14982.261773951235 11981.420105861262 14815.773381656621 13323.89129766437 12217.084527966605 9598.695435683921 10245.302061563298 1.1780161135127956 1.1445186126779616 1.1744211659432486 1.4623543243453323 1.169455037427472 1.4461041063142583 1.300487893631837 1.1924572310855264 0.936887500046952 1.0 13.322674899408153 -8.142777920432946 3.7204145371371737 0.9685851260967858 1.2690815859560292 0.5456751825722707 0.10740814261356624 0.18725733609600678 4.427255084839915 0.08670908130043074 0.02902713905232701 7.198169674260728e-09 8.142777920432946 0.30049645985924334 EALS(ph)PCPSTVSTK ddPTM_PC-9_AZD4547_30min_R2 2 EALSPCPSTVSTK 13 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 EALS(0.999)PCPS(0.001)TVSTK;EALS(0.655)PCPS(0.137)T(0.208)VSTK 141.65 7.8081e-05 33695000.0 59042.0 54445.0 76983.0 118077.0 98700.0 74750.0 89344.0 113776.0 82215.0 91126.0 True False 77816.12785010898 72043.28151999603 75962.15512020134 90856.17192146473 84997.20868601344 70075.8706832975 97295.442917738 96194.53351238243 86560.71705475097 87935.70647659575 0.8849207104604304 0.8192722206555592 0.8638374349152332 1.0332113718293292 0.9665835653306045 0.7968989332217207 1.1064384061511277 1.093918925163634 0.9843636961942106 1.0 16.424161473208265 -6.091380430808045 0.5138595477486241 1.040703267836083 0.8191608407480205 0.34490756542292 0.08411696135402599 1.6317165203768451 0.7888248088923472 0.07022194745415986 0.18860145301235465 8.102509878497059e-07 6.091380430808045 -0.2215424270880625 EALS(ph)PCPSTVSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EALSPCPSTVSTK 13 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 EALS(0.992)PCPS(0.007)TVSTK;EALS(0.942)PCPS(0.057)TVSTK 121.76 0.00019226 15393000.0 34681.0 34190.0 38787.0 47151.0 59906.0 50663.0 54254.0 55644.0 49864.0 36868.0 True False 40551.80831902686 37584.15724616174 39711.829180516645 44509.282335604534 48167.849338819215 48006.14309288571 49114.66835505511 54183.40395969138 50593.16666658007 43551.8765530726 0.9311150638850236 0.8629744621993829 0.9118281994605572 1.0219831120563825 1.1059879194900262 1.102274962466545 1.1277279475019557 1.2441118098243855 1.161675929277741 1.0 15.410447262219407 -6.039431243135687 1.4515041703690863 1.1439746698510191 0.8873064831478173 0.7331516024674463 0.059676337711167454 0.19557489917758844 0.8323552399906641 0.021119436052215584 0.03592264204720376 9.132060012815842e-07 6.039431243135687 -0.2566681867032018 EALS(ph)PCPSTVSTK ddPTM_PC-9_Lapatinib_30min_R1 2 EALSPCPSTVSTK 13 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 EALS(0.997)PCPS(0.001)T(0.002)VSTK;EALS(0.978)PCPS(0.017)T(0.004)VSTK 159.18 0.00026202 31063000.0 136738.0 124476.0 145064.0 124565.0 141560.0 135354.0 127919.0 117545.0 149375.0 121197.0 True False 134788.0910453218 124187.78346978266 133137.39788323327 133725.9256366587 133233.7191176682 129565.22494558491 134542.01990752606 123006.56981911989 132550.81451151634 142145.7399651485 0.9482386955695566 0.8736651798374767 0.9366260143700127 0.9407663266549234 0.9373036374521996 0.9114956591548357 0.9465075769454172 0.865355302587885 0.9324993808749762 1.0 17.117011337270412 -11.729844316611711 1.9815883202248887 1.2050080205231608 0.9202674311200421 0.4138398790171298 0.028040420060255297 3411452.429267749 623831.9877830207 3130185.5748564326 0.007149721739304519 1.8627547666078656e-12 11.729844316611711 -0.28474058940311875 EALSY(ph)ALVLRDS(ph)TK ddPTM_PC-9_Lapatinib_30min_R1 1 EALSYALVLRDSTK 14 1 Q8N7L0 Q8N7L0 FAM216B Protein FAM216B 2 EALS(0.266)Y(0.734)ALVLRDS(0.521)T(0.479)K 86.262 0.016853 0.0 12874.0 15267.0 27411.0 15212.0 19199.0 25703.0 17877.0 21510.0 25390.0 13947.0 True False 12690.414399197538 15231.650199501677 25157.373389519875 16330.741225744407 18069.75256668629 24603.74260661945 18802.583587167206 22509.43312611565 22530.310831447016 16357.720366790656 0.7758058039041638 0.931159712842682 1.5379510607476956 0.9983506784294331 1.1046620287855875 1.5041058322875978 1.1494623435023439 1.3760739651604612 1.377350286363124 1.0 13.997684085978113 -5.0643460821797275 6.659395233659187 1.2595843497643011 0.8115538548873084 0.44379791076972763 0.18384306809432477 0.1757298703483028 15.046761420078045 0.045450613801595055 0.1257202279142398 8.622911281895223e-06 5.0643460821797275 -0.44803049487699276 EALTYDGALLGDR ddPTM_PC-9_Lapatinib_30min_R1 2 EALTYDGALLGDR 13 0 Q15056;Q15056-2 Q15056;Q15056-2 EIF4H Eukaryotic translation initiation factor 4H 0 ; 121.68 0.00089156 15855000.0 51449.0 70841.0 69108.0 69826.0 78318.0 69969.0 69769.0 73657.0 71496.0 69541.0 False True 50715.32782540892 70676.97201695819 63426.2070045945 74961.2369727075 73711.48921911234 66976.58897570534 73381.2974376612 77079.37311809852 63443.36759374312 81561.06919244204 0.6218080308112062 0.8665527894220832 0.7776529615488657 0.9190810973288942 0.9037582507064891 0.8211833125639286 0.8997098513326155 0.945051038213231 0.7778633632677069 1.0 16.31559306746555 -4.208236805039037 1.2891556953387882 0.8837218676554679 1.2284379586883566e-27 0.5605718466227412 0.06798298151622288 3.8281183633315967 1.9795529595668515 0.018644667508472327 6.419946205100767 6.191034083785986e-05 4.208236805039037 -0.8837218676554679 EAMEDGEIDGNK ddPTM_PC-9_Lapatinib_30min_R1 2 EAMEDGEIDGNK 12 0 P19338;H7BY16 P19338 NCL Nucleolin 0 ; 128.01 0.0010007999999999998 1245400.0 23097.0 26144.0 23412.0 24556.0 27085.0 29783.0 34204.0 30052.0 30105.0 29570.0 False True 22767.632544528948 26083.465174282566 21487.15573293348 26361.930156414648 25491.913551158825 28509.250517563974 35974.91575854264 31448.325630219788 26714.257880295907 34681.1351004517 0.6564846415373646 0.7520937564106097 0.6195632199089592 0.7601230490310942 0.735036886114688 0.8220391413080554 1.0373050263304124 0.9067847848443171 0.7702821087868018 1.0 15.08186349774568 -6.876012387632179 2.795350202293472 0.9219840355644913 0.7022906446259971 0.6514396401608362 0.07697482582853246 0.1744254972412528 2.755237021420398 0.029751138594906485 0.02584990324692003 1.330416469200018e-07 6.876012387632179 -0.21969339093849416 EANANGS(ph)SPEPVK ddPTM_PC-9_AZD4547_30min_R2 4 EANANGSSPEPVK 13 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 EANANGS(0.5)S(0.5)PEPVK;EANANGS(0.743)S(0.257)PEPVK;EANANGS(0.5)S(0.5)PEPVK;EANANGS(0.5)S(0.5)PEPVK 199.38 5.451300000000001e-07 117295000.0 259301.0 244581.0 280728.0 313900.0 302838.0 313351.0 244089.0 317326.0 258136.0 290521.0 True False 341753.3242041452 323637.02520786464 277005.36329558317 241535.2047066554 260794.17106438673 293757.11243454117 265812.4481369512 268290.5581260578 271780.5419649111 280349.94821771065 1.219024031845908 1.1544037274318975 0.9880699641880076 0.8615489542344663 0.9302451194385899 1.0478229594906825 0.948145165807307 0.9569845110786753 0.9694331805399699 1.0 18.09686927776678 -5.220657900942683 3.1789379439264724 0.9570689152971853 1.2054035757110466 0.7995538036312684 0.04547678432457558 0.10799799137815566 2.186358575249292 0.01277479637311642 0.03948537179773381 6.016474759247008e-06 5.220657900942683 0.24833466041386132 EANANGS(ph)SPEPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EANANGSSPEPVK 13 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 EANANGS(0.5)S(0.5)PEPVK;EANANGS(0.775)S(0.225)PEPVK;EANANGS(0.5)S(0.5)PEPVK 222.75 2.3877000000000003e-16 50670000.0 386146.0 404800.0 415836.0 428889.0 475140.0 393791.0 446035.0 426803.0 370209.0 299511.0 True False 451512.89106885524 444985.86876999907 425751.1073068115 404859.7398068992 382039.72782102943 373139.90673056414 403783.33578624704 415599.87348515965 375622.60625838226 353809.9733722282 1.2761451769304366 1.2576973580726303 1.2033326908478557 1.1442858321604286 1.0797878990796619 1.054633658780443 1.1412435097227855 1.1746414877003055 1.0616507010196854 1.0 18.43261519044669 -1.522878745636543 0.2916258006170915 1.0623635510567662 3.022723841440192 0.7201726021783652 0.04558701333512297 32.03579222216533 0.4549833350931278 0.05278855375809536 32.44620559098394 0.029999999975394206 1.522878745636543 1.9603602903834256 EANANGS(ph)SPEPVK ddPTM_PC-9_Lapatinib_30min_R1 3 EANANGSSPEPVK 13 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 EANANGS(0.773)S(0.227)PEPVK;EANANGS(0.772)S(0.228)PEPVK;EANANGS(0.772)S(0.228)PEPVK 193.31 1.4603999999999998e-06 157327000.0 162490.0 215653.0 219975.0 198663.0 229773.0 216152.0 206304.0 192604.0 209423.0 175266.0 True False 160172.86280298381 215153.66872818134 201889.50462805602 213273.33974034022 216258.203891099 206907.68283492237 216985.41166677518 201553.08497547073 185835.57641804375 205560.49457273446 0.779200610194626 1.0466683745599399 0.9821415590952496 1.0375210479213781 1.0520416597586035 1.0065537313723052 1.055579342313745 0.9805049622711149 0.90404324432236 1.0 17.649203502780146 -4.7558133406133205 24.999612262284607 1.0096720072341654 0.7792002427864982 0.7119025640855501 0.0434929115429925 99.87240170283745 443742.6693183628 0.011046838885694604 0.09460775295030598 1.7546344801582073e-05 4.7558133406133205 -0.23047176444766715 EANANGS(ph)SPEPVKAVEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EANANGSSPEPVKAVEAR 18 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 EANANGS(0.597)S(0.403)PEPVKAVEAR 62.167 0.010138 8664900.0 30280.0 2343.7 22700.0 32526.0 34071.0 62134.0 30027.0 54232.0 52713.0 31100.0 True False 35405.80594273908 2576.367047026303 23241.254090229395 30703.673670714772 27395.03213071997 58875.5836593443 27182.62518334573 52808.467463553716 53483.827901801604 36738.18381253545 0.9637331590316193 0.07012777387616043 0.6326184824166304 0.8357428289701779 0.7456828097575281 1.6025719714335835 0.7399011699122355 1.437427275475031 1.4558103409443002 1.0 15.164992686744124 -6.314174775591832 1.4098836734587428 1.2434435013069747 0.5141378952368124 0.44147434556173526 0.32539928514285116 0.3604979697943104 1.4448072669999386 0.12230145156469763 0.1627226630134473 4.85093242050314e-07 6.314174775591832 -0.7293056060701623 EANANGSS(ph)PEPVK ddPTM_PC-9_AZD4547_30min_R2 1 EANANGSSPEPVK 13 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 EANANGS(0.352)S(0.648)PEPVK 169.3 2.0265000000000003e-18 0.0 20889.0 22396.0 25495.0 25723.0 28407.0 30007.0 21749.0 28012.0 23082.0 27223.0 True False 27531.267481808347 29635.069022349748 25156.919641862944 19792.959766388347 24463.178390512516 28130.657546404087 23684.618866604185 23683.389051723232 24302.067397163057 26269.9310560363 1.048014455122912 1.128098469658534 0.9576317344800336 0.7534454401181355 0.9312235474973343 1.0708310382086148 0.9015866397244289 0.9015398251789956 0.925090642427816 1.0 14.681124793753577 -5.3663569389499655 5.394424218031467 0.922634140347877 1.0866341031163596 0.39719706082455863 0.07818333668478254 0.21188801541753757 8.851393662261307 0.021558792488632024 0.04618025226430487 4.301729136570818e-06 5.3663569389499655 0.1639999627684825 EANANGSS(ph)PEPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EANANGSSPEPVK 13 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 EANANGS(0.344)S(0.656)PEPVK 134.88 4.853e-05 13460000.0 43462.0 58391.0 51152.0 52413.0 63275.0 47992.0 60414.0 49900.0 44763.0 39422.0 True False 50819.25818637139 64187.67258732467 52371.65767504029 49476.46953523872 50876.717973388055 45475.21503491249 54691.14856051717 48590.17787342034 45417.574191723936 46568.89653561969 1.0912703964866481 1.3783378469839562 1.1246059402541817 1.0624359436430941 1.0925042626782748 0.9765147645302125 1.174413667257177 1.0434041063492798 0.9752770104179915 1.0 15.50707907700831 -5.49657738558408 6.859211932198366 1.0552632360774603 1.239714099506168 0.4341413744775422 0.08527376012070272 0.15966005752909299 28.518965671397346 0.021408751694397144 0.0427601590366644 3.187297590441118e-06 5.49657738558408 0.18445086342870765 EANANGSS(ph)PEPVK ddPTM_PC-9_Lapatinib_30min_R1 1 EANANGSSPEPVK 13 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 EANANGS(0.266)S(0.734)PEPVK 188.92 2.5676999999999998e-05 29194000.0 28273.0 38515.0 39923.0 35163.0 39655.0 34057.0 37205.0 31577.0 39986.0 27879.0 True False 27869.821835366813 38425.82088385457 36640.685047236606 37749.00432032936 37322.57086472966 32600.461500744597 39131.29285453688 33044.18269750598 35482.35560875308 32697.84800356758 0.8523442225410678 1.1751788949432398 1.1205839920486154 1.1544797784921705 1.141438141759589 0.9970216234777177 1.196754381213937 1.0105919721047274 1.0851587420946385 1.0 14.996908067971727 -9.67735230932082 10.754784344027716 1.000003177591134 1.0881383538255052 0.054111594365609306 0.09878852108197632 0.0 0.0 0.09063569760745202 0.02198238556982745 2.1020725000544085e-10 9.67735230932082 0.08813517623437117 EANANGSS(ph)PEPVKAVEAR ddPTM_PC-9_AZD4547_30min_R2 2 EANANGSSPEPVKAVEAR 18 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 EANANGS(0.013)S(0.987)PEPVKAVEAR;EANANGS(0.054)S(0.946)PEPVKAVEAR 137.39 4.8358999999999996e-05 120482000.0 123451.0 52687.5 135006.0 318908.0 232694.0 138706.0 91117.0 107945.0 73966.0 144423.0 True False 162705.850059683 69717.7040147819 133215.7322286466 245388.68767948396 200388.45469081312 130032.69189294243 99226.23648298171 91264.58057933253 77875.69175541816 139366.79472894 1.1674649644926975 0.5002461608619085 0.9558642177840364 1.7607399822658627 1.4378493462560904 0.9330249156253335 0.7119790383065833 0.6548516865644834 0.5587822544594045 1.0 17.088527342771386 -7.042277709302731 4.383495686327605 0.7101763265709393 1.1528806086972028 0.2860168899969934 0.32078326806044744 0.3179390640780189 13.482128204603727 0.13917372885763746 0.11052268983670653 9.072402105373129e-08 7.042277709302731 0.44270428212626345 EANANGSS(ph)PEPVKAVEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EANANGSSPEPVKAVEAR 18 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 EANANGS(0.08)S(0.92)PEPVKAVEAR;EANANGS(0.174)S(0.826)PEPVKAVEAR;EANANGS(0.005)S(0.995)PEPVKAVEAR 112.82 7.9975e-05 91283000.0 122695.0 24929.1 60537.0 147445.0 136597.0 235951.0 145968.0 227457.0 197700.0 118986.0 True False 143464.84016328852 27403.896297317646 61980.431667851 139184.13467313958 109831.79841976933 223577.31419200383 132140.85432319617 221486.49476061208 200590.9884883456 140557.21990734249 1.0206863813745233 0.19496612351455672 0.44096227649287223 0.9902311298195278 0.7814027517915634 1.590649803257275 0.9401214282005967 1.5757745842342317 1.42711266358696 1.0 17.10079803599566 -6.317730197720069 1.4324985552812997 1.3183836986900554 0.5377866225795538 0.49380494615934223 0.3080903595166023 0.3140042162214574 1.2969894988355424 0.11500783823555785 0.15200980524444957 4.811381591959767e-07 6.317730197720069 -0.7805970761105017 EANANGSS(ph)PEPVKAVEAR ddPTM_PC-9_Lapatinib_30min_R1 2 EANANGSSPEPVKAVEAR 18 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 EANANGS(0.256)S(0.744)PEPVKAVEAR;EANANGS(0.293)S(0.707)PEPVKAVEAR 76.693 0.002486 110114000.0 369310.0 72048.0 110555.0 82779.0 62974.0 91892.0 40314.0 29595.0 113304.0 50690.0 True False 364043.57167684106 71881.17728261578 101465.59465464139 88866.84380264913 59269.99313164761 87961.99337071448 42401.261662083045 30970.09174185924 100542.51037598557 59451.69895982062 6.123350182521672 1.2090685134363512 1.706689572037548 1.4947738308153014 0.9969436394358416 1.4795539052662237 0.7132052137103633 0.5209286241388968 1.69116294630933 1.0 15.859430418214831 -4.7614266567532635 10.924288988090668 1.1976454202111357 6.135554981575894 0.9379491676996257 0.3797916020221918 0.01520572762234121 59.01459768290539 0.09839407050211976 0.553295435111288 1.732101521739877e-05 4.7614266567532635 4.937909561364759 EANLQQNEEKNHSDSSTSESEVSSVS(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 1 EANLQQNEEKNHSDSSTSESEVSSVSPLK 29 1 Q9NY27-2;Q9NY27-3;Q9NY27;H7C559;C9IZ04 Q9NY27-2 PPP4R2 Serine/threonine-protein phosphatase 4 regulatory subunit 2 1 EANLQQNEEKNHS(0.003)DS(0.004)S(0.004)T(0.004)S(0.013)ES(0.039)EVS(0.127)S(0.127)VS(0.678)PLK 53.372 0.0020710999999999998 14880000.0 21340.0 15027.0 38245.0 36823.0 42688.0 50423.0 27137.0 42978.0 39863.0 43715.0 True False 28125.676100425593 19884.183880998822 37737.84631116093 28334.026259678823 36761.50804851617 47270.04183898201 29552.140428665145 36336.73763619024 41970.076798072565 42184.551155810455 0.666729296147829 0.4713617505981214 0.8945892578487933 0.671668311819317 0.8714448071934191 1.1205533908465228 0.7005441475366905 0.8613754713657836 0.9949158079945969 1.0 15.36442713081469 -5.605192303186746 0.9936854266156427 0.9152380030993272 0.5537399618647327 0.44599479924873675 0.13810601174746437 0.7011452135478331 1.198969659770408 0.05240956167329269 0.20526654281305512 2.482033831129325e-06 5.605192303186746 -0.3614980412345945 EANLQQNEEKNHSDSSTSESEVSSVS(ph)PLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EANLQQNEEKNHSDSSTSESEVSSVSPLK 29 1 Q9NY27-2;Q9NY27-3;Q9NY27;H7C559;C9IZ04 Q9NY27-2 PPP4R2 Serine/threonine-protein phosphatase 4 regulatory subunit 2 1 EANLQQNEEKNHS(0.004)DS(0.001)S(0.001)T(0.001)S(0.001)ES(0.011)EVS(0.112)S(0.112)VS(0.756)PLK 54.388000000000005 0.0011254000000000001 7553800.0 16324.0 13563.0 20510.0 35791.0 43134.0 43383.0 37352.0 37450.0 35856.0 33093.0 True False 19087.33078630359 14909.445005255679 20999.036184608143 33785.7463059876 34682.202340009804 41107.91910859327 33813.74815493821 36466.97718155493 36380.32616711245 39092.498935956115 0.48826069721390036 0.3813888958513833 0.5371627999276827 0.8642513839122339 0.8871830474902219 1.0515551634583133 0.8649676811486035 0.93283822150376 0.930621657794583 1.0 15.254604189484406 -5.7464431207398325 2.5760167717307434 0.9405876927558409 0.43250309449732727 0.9379499587033453 0.05542406619748469 0.058169801616208806 0.78659751362289 0.015898125348122776 0.029205089535866095 1.7929033523519705e-06 5.7464431207398325 -0.5080845982585136 down EANLQQNEEKNHSDSSTSESEVSSVS(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 1 EANLQQNEEKNHSDSSTSESEVSSVSPLK 29 1 Q9NY27-2;Q9NY27-3;Q9NY27;H7C559;C9IZ04 Q9NY27-2 PPP4R2 Serine/threonine-protein phosphatase 4 regulatory subunit 2 1 EANLQQNEEKNHSDS(0.001)S(0.001)T(0.001)S(0.001)ES(0.002)EVS(0.025)S(0.072)VS(0.896)PLK 54.136 0.0011835 15546000.0 27684.0 26722.0 47868.0 44919.0 55986.0 42506.0 24830.0 26534.0 51830.0 32294.0 True False 27289.22108337617 26660.126850794797 43932.477815823484 48222.493105391324 52693.013552710974 40688.11746632557 26115.575905876933 27766.866507129373 45992.3596059039 37875.974870949874 0.7204889425646563 0.7038796213597287 1.1599035527272679 1.273168367802911 1.3911988729595837 1.0742460782846426 0.6895024087131039 0.7330997182709088 1.2142884707946917 1.0 15.208995401425728 -10.641198606790324 14.191259741160932 1.0000000126884072 0.997186080016195 0.0 0.2525790577473268 0.0 0.0 0.27187776286920645 0.06594004315096293 2.2845538173517797e-11 10.641198606790324 -0.002813932672212194 EANQAINPK ddPTM_PC-9_Lapatinib_30min_R1 3 EANQAINPK 9 0 P17844-2;P17844;J3KTA4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 ;; 123.35 0.0069158 9726200.0 76630.0 75163.0 75030.0 72749.0 72289.0 78860.0 74135.0 61390.0 71098.0 70669.0 False True 75537.24214777915 74988.96469150089 68861.32302417574 78099.20414354968 68037.10314564231 75487.34163163861 77973.34755465912 64242.403515213366 63090.19454486892 82884.04248947649 0.9113604968938365 0.9047455027428469 0.8308152082823281 0.9422706928594329 0.8208709553986915 0.9107584447419175 0.9407522269990528 0.7750877199717908 0.7611862627583503 1.0 16.338806748612704 -7.760203149175752 24.999463341177268 0.8261027518258458 0.8920838962018975 0.07018252284655391 0.07186796899445816 61.335197545291905 1240429.5726887162 0.03409553564148858 0.018280383150989756 1.736988130764964e-08 7.760203149175752 0.06598114437605174 EAPAEGEAAEPGS(ph)PTAAEGEAASAASSTSSPK ddPTM_PC-9_AZD4547_30min_R2 3 EAPAEGEAAEPGSPTAAEGEAASAASSTSSPK 32 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 EAPAEGEAAEPGS(0.535)PT(0.463)AAEGEAAS(0.002)AASSTSSPK;EAPAEGEAAEPGS(0.853)PT(0.147)AAEGEAASAASSTSSPK;EAPAEGEAAEPGS(0.988)PT(0.012)AAEGEAASAASSTSSPK 162.08 9.8296e-18 155428200.0 199594.0 211488.0 242622.0 281200.0 234525.0 230239.0 188248.0 272434.0 209641.0 202963.0 True False 263060.74018689524 279847.36012675054 239404.67375360162 216373.68449669197 201965.25194617367 215842.11893313314 205001.7073153022 230335.58521052275 220722.19526941582 195857.32714712925 1.3431243243163549 1.4288327335159 1.222342187758742 1.1047515436282387 1.0311855823216463 1.1020374988115262 1.0466889868322549 1.1760376216994588 1.1269539847422094 1.0 17.579443575873768 -5.5204508271287285 2.7120140820649805 1.0877383055623544 1.3860403259141887 0.843018433741818 0.05203075999768971 0.09821888880407467 1.4417335755019691 0.014722915236057676 0.032903719551560906 3.0168184322487846e-06 5.5204508271287285 0.2983020203518343 EAPAEGEAAEPGS(ph)PTAAEGEAASAASSTSSPK ddPTM_PC-9_Lapatinib_30min_R1 3 EAPAEGEAAEPGSPTAAEGEAASAASSTSSPK 32 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 EAPAEGEAAEPGS(0.941)PT(0.059)AAEGEAASAASSTSSPK;EAPAEGEAAEPGS(0.541)PT(0.456)AAEGEAAS(0.002)AAS(0.001)STSSPK;EAPAEGEAAEPGS(0.876)PT(0.124)AAEGEAASAASSTSSPK 136.86 9.4873e-18 103119000.0 114387.8 118889.0 136548.0 111613.4 191499.0 222233.0 242045.0 248469.0 269104.0 216448.0 True False 112756.60899584647 118613.71982501821 125321.5505305227 119821.82176738736 180235.40532151982 212728.61264042565 254576.90576471953 260013.7768206798 238794.67372925236 253860.74840116914 0.44416716529039896 0.4672393056904418 0.4936625741466755 0.4719982215526925 0.7099774441565058 0.8379736291656105 1.0028210637842234 1.0242378093433617 0.9406522088711868 1.0 17.953677819147977 -6.640859492281575 1.4118596083645745 0.9975764545899307 0.4581504206389662 0.9816773409450043 0.03210786299367493 0.04770380625040526 0.19790577956580174 0.013905379483558645 0.013958836778523538 2.2863383850236982e-07 6.640859492281575 -0.5394260339509644 down EAPAEGEAAEPGSPT(ph)AAEGEAASAASSTSSPK ddPTM_PC-9_AZD4547_30min_R2 1 EAPAEGEAAEPGSPTAAEGEAASAASSTSSPK 32 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 EAPAEGEAAEPGS(0.224)PT(0.763)AAEGEAAS(0.012)AAS(0.001)STSSPK 77.52199999999999 1.1465000000000002e-06 8865100.0 26246.0 25574.0 34890.0 31926.0 27117.0 27875.0 25369.0 32937.0 30681.0 26856.0 True False 34591.68204928634 33840.29537317256 34427.335803279 24565.953951782994 23352.27262349169 26131.971843437 27626.79185373495 27847.343466964434 32302.7350234971 25915.77961433019 1.3347729670520423 1.305779562751818 1.328431415748046 0.9479149119712067 0.901083161340784 1.008342107871116 1.0660220246069176 1.0745323459829925 1.246450444640887 1.0 14.661543173959315 -5.751869493989025 24.999416998192622 1.032625609192858 1.3212732479434548 0.698530483193669 0.08671768361561671 120.09887085232796 313731.26222214266 0.025807938202680188 0.04397342588119227 1.770640958104697e-06 5.751869493989025 0.28864763875059674 EAPAEGEAAEPGSPT(ph)AAEGEAASAASSTSSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EAPAEGEAAEPGSPTAAEGEAASAASSTSSPK 32 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 EAPAEGEAAEPGS(0.211)PT(0.789)AAEGEAASAASSTSSPK;EAPAEGEAAEPGS(0.469)PT(0.531)AAEGEAASAASSTSSPK 124.12 1.1639e-16 74449000.0 82751.0 77809.0 79737.0 91695.0 126480.0 136472.0 149026.0 126719.0 146135.0 122412.0 True False 96759.10989324964 85533.36329823328 81638.23248425632 86557.62642920106 101697.151944277 129315.16807477454 134909.17842519318 123392.76051987878 148271.9479147413 144604.32658714097 0.6691301164833473 0.5914993369627115 0.5645628620597307 0.598582549167642 0.7032787631218808 0.8942690106637098 0.9329539551770927 0.8533130607646118 1.0253631507034484 1.0 17.14175119306354 -6.687873773621268 2.1435693949618444 0.9419367759085584 0.6011450346157969 0.9132081548323231 0.04959148099494173 0.08506700125166912 0.8018457359995171 0.018906856957185275 0.01827585576930576 2.0517584295592903e-07 6.687873773621268 -0.34079174129276146 EAPAEGEAAEPGSPT(ph)AAEGEAASAASSTSSPK ddPTM_PC-9_Lapatinib_30min_R1 1 EAPAEGEAAEPGSPTAAEGEAASAASSTSSPK 32 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 EAPAEGEAAEPGS(0.172)PT(0.828)AAEGEAASAASSTSSPK 91.40700000000001 2.0849999999999997e-09 10818000.0 53246.0 49607.0 60534.0 52319.0 93464.0 104740.0 104590.0 119530.0 117740.0 101840.0 True False 52486.70227587947 49492.138039344994 55557.12818799741 56166.71379106764 87966.63127729397 100260.51436086521 110005.15843719973 125083.80016571838 104478.88134283457 119442.90830672972 0.4394292052994346 0.4143581125155547 0.4651354272563973 0.4702390002663981 0.7364742915619186 0.8394011480647804 0.9209852639782194 1.0472266787451527 0.8747181630451639 1.0 16.865961673526712 -6.52326678439285 1.2803433784670784 0.9683085937325083 0.42179498552735956 0.9602158848228569 0.04736083989063421 0.07383605595475376 0.25176640810461187 0.019904536384666556 0.0223429638476037 2.997320717910336e-07 6.52326678439285 -0.5465136082051487 down EAPAEGEAAEPGSPTAAEGEAASAASSTS(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 1 EAPAEGEAAEPGSPTAAEGEAASAASSTSSPK 32 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 EAPAEGEAAEPGSPTAAEGEAASAASS(0.004)T(0.083)S(0.548)S(0.365)PK 124.93 7.9463e-17 3773400.0 17196.0 31559.0 19921.0 18895.0 28288.0 19248.0 23842.0 23371.0 19703.0 18795.0 True False 16950.781886639823 31485.927074479187 18283.172277283767 20284.60133187224 26624.15545634782 18424.807909279487 25076.422100198048 24456.901980030147 17483.84065821192 22043.690707236725 0.7689629704827535 1.4283419003035944 0.82940613348751 0.9201998703970659 1.2077902838478574 0.8358313566444119 1.1375782047225742 1.1094740125346247 0.7931448907724036 1.0 14.428078169668373 -8.253767997572032 24.52734875440701 0.896572441407377 1.0357300629303798 0.06745369319460526 0.19697601117064584 1093.0810721313896 3494893.5846606162 0.13026934199903198 0.0471174346798123 5.5748348004771705e-09 8.253767997572032 0.13915762152300282 EAPAEGEAAEPGSPTAAEGEAASAASSTSS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 EAPAEGEAAEPGSPTAAEGEAASAASSTSSPK 32 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 EAPAEGEAAEPGS(0.006)PT(0.021)AAEGEAAS(0.007)AAS(0.025)S(0.063)T(0.063)S(0.133)S(0.681)PK 48.67100000000001 0.0063566000000000004 4986300.0 12735.0 16935.0 13139.0 6696.4 9278.4 14749.0 13494.0 12951.0 16616.0 11120.0 True False 16784.46509554451 22408.90756802523 12964.768275129903 5152.6484383486695 7990.254316842025 13826.742698434171 14694.939858658185 10949.720534373391 17494.287837763677 10730.692184664582 1.5641549311731708 2.088300286914407 1.2081949656200257 0.4801785709324892 0.7446168596897259 1.2885229079811094 1.3694307511363506 1.0204113906111132 1.6303037620224599 1.0 13.389455519872635 -5.3764584055130085 5.740641250139221 1.0682747017982435 1.8189258149226022 0.45204863756458336 0.324836360573767 0.19778534971852316 8.52761260338212 0.09054545509792142 0.19241613837148516 4.202827782680222e-06 5.3764584055130085 0.7506511131243587 EAPAEGEAAEPGSPTAAEGEAASAASSTSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 EAPAEGEAAEPGSPTAAEGEAASAASSTSSPK 32 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 EAPAEGEAAEPGSPTAAEGEAASAASS(0.006)T(0.017)S(0.118)S(0.859)PK 148.91 9.8296e-18 5543800.0 46767.0 65380.0 36516.0 43099.0 52982.0 47862.0 61862.0 56597.0 44699.0 50977.0 True False 46100.09400398254 65228.61662693523 33513.79543583626 46268.64423404929 49865.702926619786 45815.053831771365 65064.911666909284 59226.70323750659 39664.5279186629 59788.3065274172 0.7710553564992239 1.0909928782984222 0.5605409716775939 0.7738744734780507 0.83403772113453 0.7662878661860393 1.0882548017491076 0.9906068038630084 0.6634161464411755 1.0 15.8675757274421 -7.212606719563666 24.998776187254062 0.9347871550084663 0.8022642406924102 0.15061588760234135 0.15825338227084595 787.1397850128118 402958.7034935142 0.060591056446648035 0.046933527620622036 6.129051639204783e-08 7.212606719563666 -0.13252291431605612 EAPAPPKAEAK ddPTM_PC-9_Lapatinib_30min_R1 2 EAPAPPKAEAK 11 1 P62750 P62750 RPL23A 60S ribosomal protein L23a 0 ; 94.616 0.008502500000000001 2406100.0 51709.0 43360.0 52157.0 41387.0 44082.0 46725.0 37300.0 32544.0 49808.0 33067.0 False True 50971.620177730736 43259.60258403047 47868.852791842255 44430.73804298471 41489.18342854656 44726.68067129494 39231.21148969831 34056.11304771304 44198.09853850779 38782.586890992105 1.3142913937380938 1.115438810351205 1.234287256968941 1.1456362662931203 1.0697889634119044 1.1532670782640198 1.0115676811339886 0.8781289691540184 1.1396377106750846 1.0 15.243121417401918 -6.339594908337727 0.622858250802522 0.9943699831881502 1.2481370834491101 0.5241667367075458 0.08110971369907162 0.7296488503478862 0.6062079040195634 0.05645372200789761 0.09952539042655324 4.575147411946645e-07 6.339594908337727 0.25376710026095994 EAPATGPS(ph)PQHPQK ddPTM_PC-9_AZD4547_30min_R2 2 EAPATGPSPQHPQK 14 0 Q9H0F6;H0YCU2 Q9H0F6 SHARPIN Sharpin 1 EAPAT(0.018)GPS(0.982)PQHPQK;EAPAT(0.064)GPS(0.936)PQHPQK 98.40799999999999 0.004147 0.0 35341.0 32057.0 52726.0 62930.0 57602.0 51799.0 43394.0 56197.0 41303.0 55841.0 True False 46578.70286153424 42418.79834119784 52026.818789443605 48422.46075880799 49604.95658289516 48560.000341459825 47255.9819346831 47513.044928590956 43486.19225825428 53886.02358667756 0.864393023668016 0.7871948144951857 0.9654974579030987 0.8986089070186959 0.9205532952919386 0.9011613236472972 0.8769617572295011 0.8817322520034263 0.8070031775179183 1.0 15.717623509356683 -5.249101729844777 24.993591066931096 0.9011990031175182 0.8257939218067513 0.2732183802152033 0.05205407339115982 1033.456116780272 2093564.273407458 0.01282821802581087 0.03340866388941658 5.635056438880009e-06 5.249101729844777 -0.07540508131076695 EAPATGPS(ph)PQHPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EAPATGPSPQHPQK 14 0 Q9H0F6;H0YCU2 Q9H0F6 SHARPIN Sharpin 1 EAPAT(0.001)GPS(0.999)PQHPQK;EAPAT(0.053)GPS(0.947)PQHPQK 77.13 0.024836 0.0 24237.0 26519.0 31841.0 31250.0 36771.0 33042.0 30588.0 27033.0 30862.0 24243.0 True False 28339.84539742957 29151.631062034627 32600.21019766496 29499.163813866962 29565.986512832118 31309.219352883385 27690.483202057447 26323.412393831106 31313.298364832215 28638.063992517593 0.9895866356341009 1.0179330233234767 1.1383524461074805 1.0300683671066018 1.0324017196328972 1.0932729028423045 0.9669118418511906 0.9191756957002664 1.093415336072075 1.0 14.805646345517498 -7.273491135982421 24.970478838195493 0.9881403582465059 1.0510727662929924 0.1856150414203267 0.05612256466577108 1204.5827642860245 2495811.239634905 0.02330895172960392 0.015856585929714645 5.327320973565445e-08 7.273491135982421 0.06293240804648648 EAPATGPS(ph)PQHPQK ddPTM_PC-9_Lapatinib_30min_R1 2 EAPATGPSPQHPQK 14 0 Q9H0F6;H0YCU2 Q9H0F6 SHARPIN Sharpin 1 EAPAT(0.021)GPS(0.979)PQHPQK;EAPAT(0.018)GPS(0.982)PQHPQK 89.46 0.0087382 0.0 53321.0 50764.0 55976.0 41802.0 47547.0 50088.0 44726.0 42297.0 55582.0 40134.0 True False 52560.63276212615 50646.45907693086 51373.869353608556 44876.258527384125 44750.37894099863 47945.85300083084 47041.69343400126 44262.273032790006 49321.76985559233 47071.10842480649 1.1166219475389851 1.0759563726406784 1.0914098068388487 0.9533716122081868 0.9506973691194228 1.0185834709505877 0.9993750945794655 0.94032782558109 1.0478140733477979 1.0 15.522554205386122 -5.750453146948954 24.9925239455858 0.98497883861251 1.0927921230391546 0.6969651557516217 0.032452413707839065 115.87510940171343 263601.2496666245 0.008692685905455662 0.01487523020606821 1.776424904242246e-06 5.750453146948954 0.10781328442664462 EAPGPAGGGGGGSR ddPTM_PC-9_Lapatinib_30min_R1 1 EAPGPAGGGGGGSR 14 0 K7ELS0;K7ERU7;K7EN60;Q9BQ61 K7ELS0 C19orf43 Uncharacterized protein C19orf43 0 128.88 0.00011200000000000001 1183600.0 4581.0 2997.3 3066.9 2974.4 3042.4 2293.4 3638.7 2220.3 3434.6 2845.5 False True 4515.674099947487 2990.359936003563 2814.751320576357 3193.1472983075314 2863.452013588538 2195.3166281765166 3827.094081704162 2323.4632436036527 3047.7591800586038 3337.3408836095823 1.3530754745866564 0.8960307143600105 0.8434113921056797 0.9567938696312932 0.8580040557593571 0.6578041335118631 1.1467495275954176 0.6962019537814352 0.9132298097047328 1.0 11.704483338870626 -4.76168114223595 5.803615585775245 0.8757116624553641 1.372692713919026 0.5247056024764221 0.1334004827584681 0.10393184508022292 12.49284578026399 0.031106389559586865 0.2064366705555487 1.731086851767803e-05 4.76168114223595 0.4969810514636618 EAPGS(ph)PPLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 EAPGSPPLSPR 11 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;E9PNR0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 2 EAPGS(1)PPLS(1)PR 116.63 0.015038999999999999 13056000.0 70498.0 83568.0 102860.0 131720.0 107040.0 96582.0 91811.0 115700.0 102280.0 103110.0 True False 92914.89755050649 110579.72173869102 101496.00919246992 101353.98905371361 92179.34364489233 90542.71227202968 99982.00113852564 97821.22352150436 107686.31199124167 99500.15028424154 0.933816655402801 1.1113523087432384 1.0200588532030035 1.0186315172808909 0.9264241650044156 0.909975633337003 1.0048427148391998 0.9831263896794026 1.0822728577154384 1.0 16.602411084242583 -4.473200377822741 22.83881521771608 1.0023024083917476 0.00014408795480368462 0.12028191204450456 0.05790535364526108 195.51436429944025 420691.90999450913 0.014823429260443707 35330.685752273814 3.3635634312863925e-05 4.473200377822741 -1.002158320436944 EAPGS(ph)PPLSPR ddPTM_PC-9_AZD4547_30min_R2 2 EAPGSPPLSPR 11 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;E9PNR0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 EAPGS(0.983)PPLS(0.017)PR;EAPGS(0.999)PPLS(0.001)PR 113.24 0.0015879000000000002 44771000.0 221015.0 194657.0 310400.0 330120.0 399010.0 357580.0 210892.0 224985.0 187113.0 265660.0 True False 291293.1726024161 257576.06852489454 306283.89318824327 254015.93430315756 343614.34891394427 335220.46607268817 229660.9794480616 190218.7378909738 197003.4111812394 256359.32426061024 1.1362690763933077 1.0047462454029852 1.1947445019666247 0.9908589634326292 1.3403622041249887 1.3076195571958567 0.8958557685016848 0.7420004653218732 0.7684659481352405 1.0 17.967807846601126 -7.4225625066031355 5.556505565296592 0.8166789909585678 1.1559243174826823 0.6061955204969203 0.12290537979405777 0.15464237600185965 6.9415296960443245 0.0546021797534645 0.03611323398727143 3.779527358695271e-08 7.4225625066031355 0.33924532652411454 EAPGS(ph)PPLSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EAPGSPPLSPR 11 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;E9PNR0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 EAPGS(0.999)PPLS(0.001)PR;EAPGS(0.998)PPLS(0.002)PR 117.93 0.0011135 38824000.0 152517.0 174005.0 180430.0 171074.0 176623.0 132560.0 145697.0 108737.0 132442.0 90106.0 True False 178335.1157519401 191279.06644101746 184732.13548458525 161489.27840939164 142014.9910488146 125608.32024145704 131895.52540506644 105882.76896637477 134378.71369435257 106441.50452129662 1.675428363719334 1.7970345994381045 1.7355272862347073 1.5171645603438568 1.3342069119325584 1.1800690041573545 1.2391362372999624 0.994750773606267 1.2624653728702822 1.0 16.69970128215003 -6.257783054829142 1.1687992629708306 1.1202748007787389 1.7659568442051135 0.9034461001489217 0.08647826800433131 0.12727455974920485 0.35857060632792703 0.0341693721852954 0.050531879017809506 5.523532900206018e-07 6.257783054829142 0.6456820434263746 EAPGS(ph)PPLSPR ddPTM_PC-9_Lapatinib_30min_R1 2 EAPGSPPLSPR 11 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;E9PNR0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 EAPGS(1)PPLSPR;EAPGS(0.966)PPLS(0.034)PR 117.07 0.0011982999999999998 49989000.0 179862.0 199358.0 224152.0 206426.0 198573.0 197040.0 139075.0 136589.0 172000.0 110303.0 True False 177297.1348973486 198896.39879951885 205723.08781174175 221607.25665694947 186893.32654953894 188613.05852267434 146275.62300079875 142935.42358265957 152627.54875970414 129368.72658049113 1.3704790916917404 1.537438019657469 1.5902072568036307 1.7129893948447348 1.4446561505980113 1.4579494094758856 1.1306876620586384 1.104868443562575 1.179787053594763 1.0 16.98112937878284 -7.18473797802193 2.135550006658601 1.097848587255443 1.5463910933172813 0.826395295976787 0.09365113437681084 0.1341386910524921 1.1977252059603758 0.04605911639811225 0.031543435727115106 6.535247234278686e-08 7.18473797802193 0.4485425060618382 EAPPPVLLT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 EAPPPVLLTPK 11 0 P48634;P48634-2;P48634-3 P48634 PRRC2A Protein PRRC2A 1 EAPPPVLLT(1)PK 106.58 0.005908699999999999 11879000.0 92926.0 78722.0 81509.0 97922.0 98618.0 120040.0 76634.0 114250.0 82160.0 92858.0 True False 122474.53501912608 104167.34700738615 80428.13740296556 75347.59577981876 84926.59297059057 112533.87982371922 83454.27754027054 96595.28770381903 86502.8098670356 89607.06968377561 1.366795448744615 1.1624902742048582 0.8975646417944185 0.8408666419482447 0.9477666580359955 1.2558593894527807 0.9313358626142073 1.077987351273788 0.9653569765455451 1.0 16.451324939905597 -4.946947495094953 3.3155530190140543 0.9936143723944102 1.3649262572274834 0.5453920986185057 0.10810124440784159 0.20891654074311983 4.346734923229888 0.029399386455151885 0.1610227708050874 1.1299325118796092e-05 4.946947495094953 0.3713118848330732 EAPPPVLLT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EAPPPVLLTPK 11 0 P48634;P48634-2;P48634-3 P48634 PRRC2A Protein PRRC2A 1 EAPPPVLLT(1)PK;EAPPPVLLT(1)PK 120.87 0.0020137999999999996 11348600.0 145675.0 144994.0 108989.0 137602.0 134335.0 130392.0 127932.0 134194.0 115003.0 102110.0 True False 170334.90028759948 159388.04608803682 111587.71110308399 129892.60605170306 108013.02108186601 123554.01397800294 115813.35481252839 130671.54969029567 116684.70131069938 120621.7346976848 1.4121410267769003 1.3213874471919371 0.9251045127377511 1.0768590451567779 0.8954689745805753 1.024309709089057 0.9601367042415059 1.0833167838101383 0.967360497700909 1.0 16.88013036273074 -5.173332135783361 4.582347139016165 0.9943462639884412 1.3884022966579848 0.8688797086739501 0.058546253804529505 0.06554048662797532 2.378122621466856 0.014123895556176793 0.040643642591572035 6.709155599761602e-06 5.173332135783361 0.3940560326695436 EAPPPVLLT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 EAPPPVLLTPK 11 0 P48634;P48634-2;P48634-3 P48634 PRRC2A Protein PRRC2A 1 EAPPPVLLT(1)PK;EAPPPVLLT(1)PK 135.02 0.0001537 16008700.0 186162.0 174562.0 165785.0 166060.0 160153.0 160892.0 153213.0 139079.0 156917.0 148174.0 True False 183507.2957420701 174157.81241405735 152154.7972486065 178272.60635992122 150733.1154129128 154011.02421757038 161145.61946303328 145541.11807285168 139243.35505073538 173785.6784705556 1.0559402670983709 1.002141338381717 0.8755312784556409 1.025818743689664 0.867350616802704 0.8862124058379435 0.9272663943383348 0.837474752544184 0.801236075815806 1.0 17.406949670220676 -3.1942051082608844 0.47409689699427987 0.879008037175867 1.807468676253883 0.3855161505798429 0.06514312438719107 19.26517052507606 1.0138377401182928 0.03858442053496432 13.835163209692587 0.0006394327733454551 3.1942051082608844 0.928460639078016 EAPS(ph)PTLR ddPTM_PC-9_AZD4547_30min_R2 2 EAPSPTLR 8 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 EAPS(0.994)PT(0.006)LR;EAPS(0.947)PT(0.053)LR 136.99 0.0033176000000000004 40683000.0 94361.0 115010.0 149195.0 164040.0 172155.0 137741.0 126011.0 173590.0 140763.0 136564.0 True False 124365.835169272 152184.73335686937 147216.57681771865 126223.1123927357 148254.2498616073 129128.03349549248 137225.7348843471 146765.65420136513 148203.44480663998 131782.93592684632 0.9437172900618058 1.1548136508458746 1.1171141072425315 0.9578107476889351 1.1249882150440504 0.9798539741683431 1.0413012422224537 1.1136924000754986 1.1246026943041305 1.0 17.0078040477607 -7.746564106247174 24.80663330872763 1.089360665837668 1.0497453184508854 0.034368536795127747 0.07463831291243435 686.3252196219439 1144547.7808751245 0.03442864342205988 0.01976894738013779 1.7924039559297997e-08 7.746564106247174 -0.03961534738678263 EAPS(ph)PTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EAPSPTLR 8 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 EAPS(0.998)PT(0.002)LR;EAPS(0.909)PT(0.091)LR 119.68 0.0034489000000000004 34962000.0 47064.0 67097.0 72276.0 66577.0 81233.0 66876.0 61917.0 70361.0 68755.0 47962.0 True False 55031.00564362856 73757.94673137495 73999.33394825656 62846.90653554627 65315.97678596972 63368.90483153036 56051.77351973947 68514.09830364172 69760.41180331932 56657.13093301689 0.9712988416001718 1.30182989354995 1.3060903849109933 1.1092497184484558 1.1528288797960804 1.1184630034734462 0.9893154241432892 1.209275817101342 1.2312732864252134 1.0 15.789969926314717 EAPS(ph)PTLR ddPTM_PC-9_Lapatinib_30min_R1 2 EAPSPTLR 8 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 EAPS(0.996)PT(0.004)LR;EAPS(0.996)PT(0.004)LR 154.85 4.7565e-05 34349000.0 115984.0 124142.0 143166.0 117564.0 135541.0 121479.0 106642.0 122189.0 140552.0 108290.0 True False 114330.0468911391 123854.556826262 131395.44411674168 126210.04874200758 127568.74486385875 116283.62635138018 112163.4009566865 127866.34701287498 124721.55368182508 127007.78221264527 0.9001814290381025 0.9751729749827147 1.0345464020208643 0.9937190189708055 1.004416758102856 0.9155630019323544 0.8831222701684116 1.0067599385271702 0.9819993035781664 1.0 16.954557373131998 -6.738721675615605 24.99927737652717 0.9532634546464717 0.9848637802952783 0.05531172688228925 0.047336193817206086 648.2380342936054 713339.9934426136 0.016577861940037297 0.016567707985795276 1.8250649489190036e-07 6.738721675615605 0.03160032564880666 EAPSPLMIHSPQMS(ph)QFQSLTHQSPPQQNVQPK ddPTM_PC-9_AZD4547_30min_R2 2 EAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPK 32 0 O60885 O60885 BRD4 Bromodomain-containing protein 4 1 EAPSPLMIHS(0.008)PQMS(0.3)QFQS(0.3)LT(0.3)HQS(0.093)PPQQNVQPK;EAPS(0.001)PLMIHS(0.033)PQMS(0.242)QFQS(0.242)LT(0.242)HQS(0.239)PPQQNVQPK 54.66 0.00061678 20658600.0 9771.6 8021.0 46431.0 88602.0 62624.0 52192.0 29275.1 57902.0 37482.0 55404.0 True False 12878.765538093663 10613.631390796012 45815.294602523536 68176.17778725426 53929.73856892513 48928.42598933321 31880.527186616582 48954.57635559324 39463.22199898042 53464.32282366516 0.2408852269684612 0.19851801781538791 0.8569321031827246 1.2751714449299472 1.0087051648778007 0.9151603051385848 0.5962953517949573 0.9156494232060908 0.7381225444328013 1.0 15.706288870032289 -5.28094054933304 5.824039285558481 0.9175250689499282 0.21539125133034515 0.732687591023077 0.1677304556827153 0.08244743242510871 10.545356376312409 0.04783172421714597 0.10895863238276611 5.236721172705311e-06 5.28094054933304 -0.702133817619583 down EAPSPLMIHSPQMS(ph)QFQSLTHQSPPQQNVQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPK 32 0 O60885 O60885 BRD4 Bromodomain-containing protein 4 1 EAPSPLMIHS(0.018)PQMS(0.3)QFQS(0.3)LT(0.191)HQS(0.191)PPQQNVQPK 69.47 8.7721e-06 13878000.0 4564.2 3610.7 24254.0 25302.0 31985.0 28458.0 25664.0 20839.0 29842.0 17487.0 True False 5336.828912940875 3969.146433715011 24832.307343807217 23884.410970190795 25717.76885624366 26965.612382554154 23232.920128730297 20291.998330745617 30278.38279448263 20657.254672984167 0.25835131518809473 0.19214297817153378 1.202110722693623 1.1562238713853465 1.2449751558651063 1.305382191846632 1.1246857579344567 0.9823182534164989 1.4657505691732164 1.0 14.334360913866455 -5.262117216194868 24.999795666263925 1.1877830489997379 0.2252470647487634 0.8916137036692577 0.13387270956953146 15.375724435079063 567109.7701718346 0.033277138948910386 0.0766381199021068 5.468683430639543e-06 5.262117216194868 -0.9625359842509744 EAPSPLMIHSPQMSQFQS(ph)LTHQSPPQQNVQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPK 32 0 O60885 O60885 BRD4 Bromodomain-containing protein 4 1 EAPSPLMIHS(0.003)PQMS(0.037)QFQS(0.525)LT(0.05)HQS(0.384)PPQQNVQPK 70.407 6.9997e-06 13883000.0 16925.0 21282.0 58234.0 56256.0 75411.0 68868.0 58015.0 45594.0 61160.0 37051.0 True False 19790.068216012518 23394.736312161862 59622.51941367484 53104.15870441282 60634.75589239297 65256.44084481489 52519.39920777308 44397.2058108362 62054.3492966476 43768.05300444539 0.452157837909822 0.5345162671454846 1.3622383295784064 1.2133086819973278 1.3853656201301547 1.4909605606213963 1.1999482636899301 1.01437470399533 1.4178000856091295 1.0 15.417590587531278 -5.254832348350905 22.82281705587669 1.269855239545359 0.4933365849531631 0.7952802524265954 0.15563439331235684 63.29736101906744 218643.411078809 0.03995634940363858 0.10006648917856159 5.561188956331614e-06 5.254832348350905 -0.7765186545921959 EAPSPT(ph)CPDLGAK ddPTM_PC-9_AZD4547_30min_R2 1 EAPSPTCPDLGAK 13 0 O00257 O00257 CBX4 E3 SUMO-protein ligase CBX4 1 EAPS(0.284)PT(0.716)CPDLGAK 90.82700000000001 0.013246 13151000.0 60092.0 67849.0 81637.0 112520.0 86160.0 95109.0 63842.0 104800.0 84379.0 76409.0 True False 79200.0060087523 89779.86239048981 80554.44003933176 86580.2524166705 74198.17122985754 89161.81919488616 69523.81432165824 88605.56806442219 88839.10167685736 73733.94416708968 1.0741322318154565 1.2176191495607263 1.092501438100016 1.1742251604019662 1.0062959749137503 1.2092370780116568 0.9429010628281217 1.2016930474196752 1.2048602944057576 1.0 16.170041311049317 EAQAVPATLPELEATK ddPTM_PC-9_Lapatinib_30min_R1 2 EAQAVPATLPELEATK 16 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 192.32 3.0424e-08 6999100.0 48114.0 49902.0 56220.0 56682.0 48990.0 51169.0 53599.0 46725.0 48739.0 51642.0 False True 47427.88553697303 49786.454984969765 51597.80861547585 60850.58336560898 46108.50451804579 48980.621150764906 56374.093958078796 48896.0140779988 43249.50057557687 60568.25089136035 0.7830486243038973 0.821989313745751 0.8518953058100597 1.0046613938836544 0.7612652477079019 0.8086847552956438 0.9307532102783601 0.8072878671319446 0.7140622345715801 1.0 15.886274128948969 -11.794745202782936 2.4371784482810455 1.7524529420968311 0.8363965006056581 0.2876561922049502 0.07920585420594745 10399348.824154211 3188031.490746297 42512381.574013 0.02043126794346849 1.6041862783524539e-12 11.794745202782936 -0.916056441491173 EAQDDLVK ddPTM_PC-9_Lapatinib_30min_R1 2 EAQDDLVK 8 0 P15311;E7EQR4 P15311 EZR Ezrin 0 ; 129.1 0.01731 7842300.0 69550.0 65521.0 71092.0 71049.0 66671.0 66977.0 85647.0 65285.0 70261.0 77533.0 False True 68558.204246092 65369.290150098255 65247.09018305597 76274.18047251615 62749.54286022921 64112.54984101265 90081.38258601044 68318.37943460993 62347.4662988696 90934.4757437716 0.7539297245114186 0.7188614616780876 0.7175176372809842 0.8387817694956076 0.6900522859673178 0.7050411773601051 0.9906185948642301 0.7512923880169758 0.685630678451896 1.0 16.47253974277922 EAQLNNIDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EAQLNNIDR 9 0 Q8IYE0-2;Q8IYE0 Q8IYE0-2 CCDC146 Coiled-coil domain-containing protein 146 0 ; 73.665 0.024325 67959000.0 83006.0 98902.0 86738.0 91482.0 105766.0 95473.0 99467.0 98832.0 91701.0 66322.0 False True 97057.27635676996 108720.33693945255 88806.16287569673 86356.5601286457 85041.91154758388 90466.22780938914 90044.76568128189 96237.76472115988 93041.95364375197 78345.65359533673 1.2388342161018997 1.3877009374509037 1.133517416733666 1.1022508099132866 1.0854707012444367 1.1547064024337126 1.1493268809316757 1.2283740106150334 1.1875828380260012 1.0 16.257565619653988 -5.276602087302654 24.37551560534305 1.137279130131178 1.3132675702206134 0.5412408794848949 0.0671781671341643 382.320041678923 614616.7192423758 0.017457890116443824 0.036580518741091056 5.289296499051735e-06 5.276602087302654 0.17598844008943537 EAQLYAAQAHLK ddPTM_PC-9_Lapatinib_30min_R1 2 EAQLYAAQAHLK 12 0 P49321;P49321-3;P49321-4;P49321-2;H0YF33;Q5T624;E9PI86;E9PRH9 P49321 NASP Nuclear autoantigenic sperm protein 0 ; 87.49799999999999 0.007172199999999999 9332700.0 61564.0 51981.0 57037.0 51815.0 51639.0 58392.0 48702.0 42886.0 53425.0 46520.0 False True 60686.086070545134 51860.6411882031 52347.638029187045 55625.64794977297 48601.695546180206 55894.71027840026 51223.55125928386 44878.64012304026 47407.71390980928 54560.92001599642 1.1122628806983628 0.9505089205423656 0.9594346652116483 1.019514479108204 0.8907785193492145 1.0244458902454872 0.9388322492411401 0.8225418506484594 0.8688950607121374 1.0 15.735580351098575 -1.5228787452803378 0.4508567933256024 0.9158876187077107 4.606362266066801 0.3692362061565154 0.06402496886850877 102.38280536713185 1.2309221598918931 0.041470658974372646 348.019909143111 0.02999999999999998 1.5228787452803378 3.690474647359091 EAQQGSHS(ph)PADSR ddPTM_PC-9_AZD4547_30min_R2 1 EAQQGSHSPADSR 13 0 I3L301 I3L301 TFAP4 1 EAQQGS(0.197)HS(0.647)PADS(0.155)R 140.77 4.1805e-05 0.0 788.73 712.76 2543.6 2286.4 3020.6 2360.8 786.36 3735.3 2907.2 925.03 True False 1039.529733396846 943.1457312185223 2509.870202041284 1759.305804527867 2601.24182935129 2213.1788027977072 856.3445166188272 3158.0952136549245 3060.8686568335675 892.6449812572192 1.1645500229360517 1.0565742831939489 2.8117227506352322 1.970890826104265 2.914083296236818 2.4793494045982554 0.9593338164661322 3.537907320340276 3.4289876951109703 1.0 9.801942697016132 -5.252463616108805 24.103552506823867 2.434585357613635 1.1105618111514906 0.2692691039342673 0.8387821377259862 504.8977661876316 1355841.2075864964 0.2126082793062777 0.5440605220386395 5.59160370389777e-06 5.252463616108805 -1.3240235464621444 EAQSFISAAIEPESGKS(ph)NER ddPTM_PC-9_AZD4547_30min_R2 1 EAQSFISAAIEPESGKSNER 20 1 Q8WXA9;Q8WXA9-2 Q8WXA9 SREK1 Splicing regulatory glutamine/lysine-rich protein 1 1 EAQSFISAAIEPES(0.178)GKS(0.822)NER 103.71 0.00057778 0.0 3955.8 5551.4 8329.5 8265.6 6634.6 5824.3 4626.4 7833.6 6696.8 6865.6 True False 5213.662114248528 7345.781486456177 8219.04538760138 6360.093622246997 5713.500311532171 5460.105600277317 5038.140637475636 6623.097118220014 7050.779176211834 6625.237433726002 0.7869396631293846 1.1087574686851553 1.2405661638271321 0.9599797268956308 0.8623842343290821 0.8241373467586927 0.760446804793562 0.9996769450865123 1.0642304138897116 1.0 12.693756443122789 -4.7271584568497556 23.96539412807769 0.9721164977866162 0.7869373032624178 0.15514519020657802 0.13403297846985893 7392.121082093804 5167233.157217511 0.037909996647860676 6.685953844999288 1.8743105216458244e-05 4.7271584568497556 -0.1851791945241984 EAQSFISAAIEPESGKS(ph)NER ddPTM_PC-9_Lapatinib_30min_R1 3 EAQSFISAAIEPESGKSNER 20 1 Q8WXA9;Q8WXA9-2 Q8WXA9 SREK1 Splicing regulatory glutamine/lysine-rich protein 1 1 EAQSFISAAIEPES(0.088)GKS(0.912)NER;EAQSFISAAIEPES(0.149)GKS(0.851)NER;EAQSFISAAIEPES(0.303)GKS(0.697)NER 64.707 0.0031919 11267000.0 31464.8 41336.4 40359.0 41244.9 44466.0 38910.0 47741.5 42306.3 42043.3 39246.3 True False 31016.106182062384 41240.68810550086 37040.83881024525 44278.18753495303 41850.59730351961 37245.910003640114 50213.32126904645 44272.005144741335 37307.94081842365 46029.9706625924 0.6738241570783474 0.8959529522145951 0.8047113277946877 0.961942553896455 0.9092032147987162 0.8091664945141729 1.0908831908045027 0.9618082416185477 0.8105141124659252 1.0 15.490285902603407 -3.855948033124048 0.7365291374012203 0.9356328081025962 4.202519589713249e-14 0.41412279710493294 0.08727744840175279 9.963271448086592 1.4963980626615572 0.03354972152764544 10.599542153176161 0.00013933235154904905 3.855948033124048 -0.9356328081025541 EAQSSQATPVQTS(ph)QPDSSNIVKVSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAQSSQATPVQTSQPDSSNIVKVSPR 26 1 H7C5E4;Q8IZH2-2;Q8IZH2 H7C5E4 XRN1 5-3 exoribonuclease 1 1 EAQSSQAT(0.001)PVQT(0.035)S(0.435)QPDS(0.063)S(0.081)NIVKVS(0.386)PR 82.84899999999999 5.2757e-06 6676600.0 18937.0 14228.0 20633.0 21003.0 23195.0 21615.0 24676.0 22944.0 17148.0 17731.0 True False 22142.660077201115 15640.461810423783 21124.96897108825 19826.270002644735 18650.106256700692 20481.471348967196 22338.510641230878 22341.744311177466 17398.75705917124 20945.489941481224 1.0571564637095918 0.7467221752330001 1.0085688628009402 0.9465651105816367 0.8904115544113069 0.9778463719965286 1.0665069522671258 1.0666613372901366 0.8306684211150438 1.0 14.354352010608903 -6.940070450000165 6.987785025685238 1.0000826904037432 0.9254586301927399 0.07946926585661362 0.09768731352179685 0.4829958753168219 45.4939389696261 0.03353936620144242 0.029496226496911884 1.1479673864285453e-07 6.940070450000165 -0.07462406021100332 EAQSSQATPVQTSQPDSSNIVKVS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 EAQSSQATPVQTSQPDSSNIVKVSPR 26 1 H7C5E4;Q8IZH2-2;Q8IZH2 H7C5E4 XRN1 5-3 exoribonuclease 1 1 EAQSSQAT(0.002)PVQT(0.005)S(0.016)QPDS(0.185)S(0.185)NIVKVS(0.608)PR;EAQSSQATPVQTSQPDS(0.014)S(0.014)NIVKVS(0.973)PR;EAQSSQATPVQTSQPDS(0.105)S(0.152)NIVKVS(0.743)PR;EAQSSQATPVQTSQPDS(0.018)S(0.026)NIVKVS(0.956)PR 142.09 5.5951e-12 43101000.0 114411.0 81649.0 141401.0 170654.0 150054.0 140711.0 111901.0 149406.0 113757.0 124674.0 True False 150791.31810336452 108040.4425167814 139525.930350228 131312.35687801708 129221.59222057836 131912.318925986 121859.97221903875 126318.73570833045 119769.96278048171 120309.20120781206 1.2533648016073202 0.8980231057320494 1.159727842504935 1.0914573080008991 1.0740790473487707 1.0964441422741364 1.0128898787096758 1.0499507472428316 0.9955178953736139 1.0 16.876387458008587 -7.449482361399175 1.2378964433727715 1.0060688152900061 1.0903930662269674 0.17304591270330216 0.08436456551113299 0.9538615597415794 2.7713615286248494 0.05764498658610975 0.028244018659050293 3.55236545901161e-08 7.449482361399175 0.08432425093696128 EAQSSQATPVQTSQPDSSNIVKVS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EAQSSQATPVQTSQPDSSNIVKVSPR 26 1 H7C5E4;Q8IZH2-2;Q8IZH2 H7C5E4 XRN1 5-3 exoribonuclease 1 1 EAQSSQATPVQTSQPDS(0.039)S(0.059)NIVKVS(0.902)PR;EAQSSQATPVQTSQPDS(0.037)S(0.05)NIVKVS(0.913)PR 130.16 9.0798e-12 14094200.0 59378.0 52446.0 61189.0 64405.0 73984.0 65138.0 66504.0 62075.0 60303.0 45119.0 True False 69429.52263104242 57652.492276460915 62647.97782057474 60796.596653827226 59487.36629858779 61722.048611104576 60204.25967273533 60445.59702389915 61184.81729293233 53298.71753819255 1.302649028680492 1.0816862945182228 1.1754124810917401 1.1406765389854245 1.11611252664683 1.1580400328934009 1.129563007394961 1.1340910216195226 1.1479604035329516 1.0 15.701813199146487 -14.522878745280336 0.14596039445051137 0.4909818216710822 1.197254983030549 0.4664041946842138 0.052570910543368245 125.39926226004758 1.097081958048576 18.648235792419086 0.2718826839812289 3.0000000000000132e-15 14.522878745280336 0.7062731613594668 EAQSSQATPVQTSQPDSSNIVKVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 EAQSSQATPVQTSQPDSSNIVKVSPR 26 1 H7C5E4;Q8IZH2-2;Q8IZH2 H7C5E4 XRN1 5-3 exoribonuclease 1 1 EAQSSQATPVQTSQPDS(0.321)S(0.321)NIVKVS(0.358)PR;EAQSSQATPVQT(0.002)SQPDS(0.035)S(0.055)NIVKVS(0.908)PR 106.27 4.002e-10 21125500.0 75154.0 62710.0 96472.0 69519.0 74033.0 70405.0 66341.0 56511.0 72689.0 58449.0 True False 74082.29017844431 62564.79884789089 88540.44455268916 74631.65916858558 69678.52449447816 67393.94227207101 69775.812370994 59136.707363548216 64501.999370896105 68551.83177160294 1.0806755744363978 0.9126641437728563 1.2915839338572765 1.0886894958144817 1.0164356326265513 0.9831092843238717 1.017854819743826 0.8626568515422973 0.9409230607549651 1.0 16.06490759628334 -6.7189229217183275 1.5960883021650627 0.9448672841541235 1.0918104783293359 0.30502692585734337 0.09374914641503479 0.48167295665572035 2.5457352226169436 0.041406493994103725 0.03894329128863187 1.9101922480711233e-07 6.7189229217183275 0.1469431941752124 EAQTLDSQIQET(ph)SI ddPTM_PC-9_AZD4547_30min_R2 2 EAQTLDSQIQETSI 14 0 E7EVA0;P27816-4;P27816;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 EAQTLDSQIQET(0.61)S(0.39)I;EAQTLDSQIQET(0.5)S(0.5)I 152.04 0.00029244 5293800.0 26860.0 23531.0 31929.0 52666.0 38379.0 39434.0 30535.0 42931.0 27952.5 34100.0 True False 35400.92127729296 31136.93557621506 31505.60059796199 40524.66738158879 33050.73831976205 36968.18574615587 33252.5558458669 36297.00040623768 29430.01208384022 32906.16937923219 1.0758141085736725 0.9462339787221258 0.9574375016086154 1.2315218740460505 1.0043933688805815 1.1234423952575685 1.0105264901132285 1.1030454498646542 0.8943615327773202 1.0 15.006070471060662 -8.26009859759583 24.99816138372312 0.9471807662422707 1.0543600370187476 0.2141994985061637 0.08370917193428838 183.30635557987347 3417822.4973856458 0.06364003841465204 0.02103249951995106 5.494161261090729e-09 8.26009859759583 0.10717927077647693 EAQTLDSQIQET(ph)SI ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EAQTLDSQIQETSI 14 0 E7EVA0;P27816-4;P27816;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 EAQTLDSQIQET(0.578)S(0.422)I;EAQTLDSQIQET(0.5)S(0.5)I 150.26 0.0005675 2540800.0 25285.5 21673.7 20263.3 24741.0 27707.7 23565.9 24530.8 19107.8 19924.7 21469.0 True False 29565.835738610614 23825.321699506752 20746.453920993183 23354.841981404254 22278.5750863887 22330.062718604026 22207.065036387845 18606.240496387603 20216.061043670947 25361.1597514895 1.1657919443874867 0.9394413320592507 0.8180404257646267 0.9208901410761623 0.8784525354791887 0.8804827120452386 0.875632867502583 0.733651011180387 0.797126836539233 1.0 14.630333100163421 -4.788679522354008 2.717333991756703 0.8573272442887996 1.2230951428203929 0.6397912554889782 0.06817710370469782 0.2778916557058647 2.7956992566657943 0.017827300928401266 0.23131548869883584 1.6267487348429948e-05 4.788679522354008 0.3657678985315933 EAQTLDSQIQET(ph)SI ddPTM_PC-9_Lapatinib_30min_R1 2 EAQTLDSQIQETSI 14 0 E7EVA0;P27816-4;P27816;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 EAQTLDSQIQET(0.5)S(0.5)I;EAQTLDSQIQET(0.836)S(0.164)I 152.69 4.0656e-05 5175000.0 22439.5 19495.6 22569.2 18374.6 18532.4 17272.8 16896.4 19000.7 20674.7 14971.4 True False 22119.508615099694 19450.459136006084 20713.64749563138 19725.929379868732 17442.360668100264 16534.082608863413 17771.21291727986 19883.54188746562 18346.097571757295 17559.18654186346 1.2597114656971047 1.107708440230621 1.1796473285506286 1.1233965384922284 0.9933467377042401 0.9416200784383684 1.01207495432154 1.1323726096343123 1.0448147770409373 1.0 14.099938390755126 -6.077605701893729 3.733643535910477 1.023402994151406 1.173131211094116 0.6226899632941496 0.05713782867608886 0.1796649845379853 4.764651874538296 0.01858243741995797 0.02536678020049037 8.363620108352276e-07 6.077605701893729 0.1497282169427101 EARRTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EARRTR 6 2 Q08AM2;A2A2L3;Q9BZ11-2;Q9BZ11;Q9Y5B6-2;Q9Y5B6 Q08AM2 ADAM33;PAXBP1 Disintegrin and metalloproteinase domain-containing protein 33;PAX3- and PAX7-binding protein 1 0 39.021 0.046431 23557000.0 93854.0 78847.0 77837.0 83619.0 99914.0 77865.0 76818.0 60319.0 69613.0 65837.0 False True 109741.62849900362 86674.40907833034 79692.92927846638 78934.09852645558 80336.56893865016 73781.62232650153 69541.24292584186 58735.69016326333 70630.9584301429 77772.72693459467 1.4110554280974894 1.114457631802236 1.024689919198623 1.0149328901998975 1.032965823690503 0.9486824653654027 0.8941597609702521 0.7552222029280121 0.9081712987837258 1.0 16.246976704241796 -1.5228787453807533 0.4889408715216549 0.8915662602861126 15.516291501504972 0.815101773894458 0.07000944027023312 43.7874072289275 0.47941377246776934 0.04233391733731677 653.9981313894489 0.029999999993063527 1.5228787453807533 14.62472524121886 EAS(ph)AESDVGK ddPTM_PC-9_AZD4547_30min_R2 1 EASAESDVGK 10 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 EAS(0.94)AES(0.06)DVGK 95.01799999999999 0.0060786 6620400.0 21543.0 21240.0 29329.0 34924.0 39056.0 31579.0 27769.0 31116.0 26878.0 26440.0 True False 28393.225877763285 28105.414629161867 28940.078296771826 26872.81137042127 33633.74855563266 29604.360137897664 30240.387204318904 26307.737174547343 28298.71620747547 25514.343647709666 1.1128338737536776 1.101553503285388 1.1342670106024726 1.053243294888111 1.3182290330502717 1.160302633948224 1.1852308498256618 1.0310959802765256 1.1091296957590264 1.0 14.63902090865682 -7.765371638709071 24.999993565055327 1.0525846092668245 1.1524836975356525 0.3203081514013101 0.07026790664218653 136.0137141339914 864704.2794358998 0.03778933411573843 0.019221576340306495 1.7164389506503053e-08 7.765371638709071 0.09989908826882798 EAS(ph)AESDVGK ddPTM_PC-9_Lapatinib_30min_R1 3 EASAESDVGK 10 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 EAS(0.834)AES(0.166)DVGK;EAS(0.998)AES(0.002)DVGK;EAS(1)AESDVGK 145.23 2.3348000000000002e-07 6861900.0 50060.0 54520.0 86697.0 80737.0 80236.0 78828.0 71125.0 75858.0 93657.0 117276.0 True False 49346.135220120304 54393.762289698825 79569.10732009797 86674.66831073651 75516.67623004546 75456.71019704311 74807.5044827023 79382.63961324397 83108.36240806754 137547.00033955261 0.3587583524053812 0.39545582350338987 0.5784866781803406 0.6301458272210142 0.5490245228439933 0.5485885552630623 0.5438686725121614 0.5771310127976447 0.6042179197140161 1.0 17.06956515176858 -14.522878745280318 0.1561250328078977 2.6941545933491335 0.40371566227836175 0.8315450191145234 0.06690772337201441 59.56634870650048 0.5394550270331812 31.27092140713151 0.34527916193452995 3.000000000000136e-15 14.522878745280318 -2.2904389310707716 EAS(ph)LQFVVEPSEATNR ddPTM_PC-9_AZD4547_30min_R2 1 EASLQFVVEPSEATNR 16 0 H0Y8J2;Q03188;Q03188-2 H0Y8J2 CENPC Centromere protein C 1 EAS(1)LQFVVEPSEATNR 94.569 0.015946000000000002 0.0 1179.8 1664.0 4144.8 3903.1 4434.7 3779.9 4649.0 2612.9 2497.0 3181.7 True False 1554.951858635526 2201.8554587064664 4089.8372438357915 3003.3005972938736 3819.018453494062 3543.5422554621514 5062.751993693635 2209.136343468786 2628.9863222734666 3070.3096514341087 0.5064478945663428 0.7171444279823709 1.3320601855013132 0.9781751478685754 1.2438544925624162 1.1541318817165562 1.64893856596154 0.7195158124969324 0.8562609706305992 1.0 11.584168448420527 -5.080938702254951 4.567585811277995 1.1253126635708375 0.5463905269800794 0.41070950498119063 0.24703226085817914 0.19595557541487274 7.2089532335989315 0.06513410088970605 0.19907333111877848 8.299679036349613e-06 5.080938702254951 -0.5789221365907581 EAS(ph)LQFVVEPSEATNR ddPTM_PC-9_Lapatinib_30min_R1 1 EASLQFVVEPSEATNR 16 0 H0Y8J2;Q03188;Q03188-2 H0Y8J2 CENPC Centromere protein C 1 EAS(0.912)LQFVVEPS(0.086)EAT(0.003)NR 93.115 0.017125 0.0 3112.3 2975.8 4274.0 2819.5 3638.2 3327.9 3482.0 2824.7 4848.0 984.79 True False 3067.918031274081 2968.909717932606 3922.6082181171055 3026.855435576278 3424.2082289764066 3185.5734747137994 3662.28092244315 2955.9458740743307 4301.967188296779 1155.0096393498086 2.6561839198165558 2.570463151808758 3.3961692478387153 2.6206321856155164 2.9646577070161957 2.7580492544694772 3.170779530900507 2.5592391382450503 3.724615831534092 1.0 10.173689176636005 -10.73575547495979 5.012801226005487 0.9997823507513652 2.920657650519454 0.7099803148155126 0.3710282534090943 0.0008377631339916097 0.00013154810627359268 0.33347815101567674 0.08087169031204373 1.8375726785276577e-11 10.73575547495979 1.920875299768089 EAS(ph)PAPLAQGEPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EASPAPLAQGEPGR 14 0 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 EAS(1)PAPLAQGEPGR;EAS(1)PAPLAQGEPGR 115.09 0.0019577 0.0 22533.8 28986.0 28371.0 28181.0 27986.0 20732.3 27718.0 20971.0 17994.300000000003 17557.8 True False 26348.327277162945 31863.5385181996 29047.47223761667 26602.109934034703 22502.34419918196 19645.06169087173 25092.350379058083 20420.53347061117 18257.432595628958 20740.890152531665 1.2703566280614444 1.5362666830531517 1.4004930368946142 1.2825924894447025 1.084926636884738 0.9471657940618246 1.2098010352750108 0.984554342674565 0.8802627303534717 1.0 14.340190192267839 -6.163048038618167 2.070924522393933 1.014256728013395 1.4166308060984931 0.7618311994734411 0.0993786082595749 0.15668886165967316 1.3211810156406112 0.03339583902120803 0.046496487919295226 6.869924455117673e-07 6.163048038618167 0.4023740780850982 EAS(ph)PAPLAQGEPGR ddPTM_PC-9_Lapatinib_30min_R1 2 EASPAPLAQGEPGR 14 0 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 EAS(1)PAPLAQGEPGR;EAS(1)PAPLAQGEPGR 151.22 0.00024139 7153600.0 18605.0 21306.0 21988.0 17968.6 24570.0 19201.6 24316.0 24432.0 26084.0 17835.699999999997 True False 18339.689288260863 21256.66726603675 20180.231516134518 19290.070785492422 23124.84090647856 18380.392329115803 25574.963500898222 25567.19991340109 23146.14524330305 20918.576980423622 0.8767178238473784 1.0161622029036452 0.9647038388423803 0.9221502401212465 1.105469120969349 0.8786636082519788 1.2225957590151673 1.2222246253809628 1.106487561986844 1.0 14.35249709284018 -7.265758680637133 24.99979139661607 1.156345708185026 0.9681857223365531 0.49433488669972414 0.08678673968915449 291.66823912229324 1688143.0646425032 0.033796961315692334 0.023685615734035038 5.42302141420189e-08 7.265758680637133 -0.18815998584847282 EAS(ph)PAPLAQGEPGREDLPTR ddPTM_PC-9_AZD4547_30min_R2 1 EASPAPLAQGEPGREDLPTR 20 1 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 EAS(0.999)PAPLAQGEPGREDLPT(0.001)R 79.17699999999999 0.00078269 72754000.0 38413.0 39314.0 40474.0 33081.0 37393.0 43022.0 40143.0 46340.0 44674.0 46342.0 True False 50627.534959964774 52021.4816728281 39937.288314758196 25454.686546355108 32201.62740016317 40331.82753895412 43715.649232704585 39179.21778726455 47035.376436221384 44719.58068540702 1.1321111285930652 1.1632819645333539 0.8930604380150329 0.5692067357568389 0.7200789208354824 0.9018829541958403 0.9775505173054979 0.8761087914236546 1.0517848270337218 1.0 15.448619040317315 -5.293497275470008 5.680016255099313 0.8564384957802619 1.149002911916079 0.398987129001952 0.13350017279855272 0.17187482811904176 17.027386350756125 0.038242021334425766 0.08530264199084238 5.087480112460696e-06 5.293497275470008 0.2925644161358171 EAS(ph)PAPLAQGEPGREDLPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EASPAPLAQGEPGREDLPTR 20 1 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 EAS(0.901)PAPLAQGEPGREDLPT(0.099)R;EAS(0.998)PAPLAQGEPGREDLPT(0.002)R 81.60600000000001 0.0058976 67042400.0 42573.4 58291.9 62717.9 59205.1 61416.4 50834.5 52393.8 31073.8 42710.5 39940.0 True False 49780.23575702143 64078.734594253794 64213.33259496027 55888.03019252397 49382.29730131636 48168.64933097725 47430.67996573681 30258.145675412594 43335.06026217246 47180.80583513398 1.0550950725803785 1.3581526101560666 1.3610054228268975 1.1845501407461339 1.046660743224165 1.0209374019446624 1.0052960971348386 0.6413232063298155 0.9184891926941672 1.0 15.525912439170133 -6.698404597791173 1.120102113622194 0.8552236522123082 1.2666587723789866 0.600047462524275 0.12626851314024126 0.31016558453949306 0.8285724467013416 0.0655948691592148 0.06302957798836724 2.002605489034039e-07 6.698404597791173 0.4114351201666784 EAS(ph)PAPLAQGEPGREDLPTR ddPTM_PC-9_Lapatinib_30min_R1 1 EASPAPLAQGEPGREDLPTR 20 1 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 EAS(0.979)PAPLAQGEPGREDLPT(0.021)R 81.477 0.00058747 68805000.0 29961.0 54041.0 55289.0 51998.0 56236.0 48909.0 50725.0 57102.0 54166.0 42486.0 True False 29533.750645825505 53915.87138476914 50743.35184171187 55822.10638024303 52928.309044229936 46817.27608244756 53351.292300668785 59755.167381099775 48065.25468673332 49829.64849096349 0.5926943404222768 1.082003847459343 1.0183365401607052 1.1202588834309408 1.0621850775011665 0.9395465852210012 1.0706736634986285 1.1991890208082896 0.964591486039679 1.0 15.604716776526294 -4.7594582988792355 24.994166198475945 1.0556420568859657 0.5926937515560844 0.7838901543540401 0.0721116483262418 22.749784904862523 286946.7873597458 0.017729839940441517 0.11249023981483398 1.7399697625734684e-05 4.7594582988792355 -0.4629483053298813 EAS(ph)PSTLNDK ddPTM_PC-9_AZD4547_30min_R2 1 EASPSTLNDK 10 0 P54253 P54253 ATXN1 Ataxin-1 1 EAS(0.925)PS(0.064)T(0.01)LNDK 117.86 0.00092161 17471000.0 50527.0 50003.0 57457.0 70287.0 72889.0 69595.0 62180.0 73381.0 57296.0 66377.0 True False 66593.53497311185 66165.49188804057 56695.08263826311 54083.41807332489 62769.62050572277 65243.21364821511 67713.89954137888 62041.6525776275 60324.5495878977 64053.16143358635 1.039660392752971 1.032977770451571 0.8851254390784056 0.8443520485620587 0.9799613180811626 1.0185791331449372 1.0571515601394348 0.9685962595609823 0.9417887928989318 1.0 15.9669821581101 -6.513209936048269 24.84258787268294 0.9990353141045996 0.9467977240060743 0.11100684177312414 0.061897619149925566 1008.8238666801922 2592031.6322963545 0.022191117781706803 0.023477529074118722 3.067538795132377e-07 6.513209936048269 -0.052237590098525244 EAS(ph)PSTLNDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EASPSTLNDK 10 0 P54253 P54253 ATXN1 Ataxin-1 1 EAS(0.463)PS(0.463)T(0.074)LNDK;EAS(0.682)PS(0.271)T(0.046)LNDK 120.06 0.00073747 17543500.0 94974.0 83921.0 86459.0 103876.0 100797.0 88624.0 101391.0 76289.0 95120.0 70687.0 True False 111051.22237799523 92252.1222654324 88520.51045758362 98056.16449053574 81046.55142731863 83976.4014263646 91786.51047272823 74286.49458487704 96510.95005063966 83501.99354201574 1.3299230074323618 1.1047894589368557 1.0601005641026127 1.1742972871802966 0.9705942096644482 1.0056813959071544 1.0992134029296434 0.8896373779088073 1.1557921668310613 1.0 16.349523020715154 -1.5228787475920278 0.7744600898190838 1.0294776441454547 61.39850818442029 0.5341979581475381 0.08034889494058543 327.07420888919285 1.2716377863635915 0.027975151617722155 34549.23372581633 0.029999999840314096 1.5228787475920278 60.369030540274835 EAS(ph)PSTLNDK ddPTM_PC-9_Lapatinib_30min_R1 2 EASPSTLNDK 10 0 P54253 P54253 ATXN1 Ataxin-1 1 EAS(0.833)PS(0.149)T(0.017)LNDK;EAS(0.692)PS(0.239)T(0.07)LNDK 129.0 0.00026087 30945000.0 153346.0 164394.0 164422.0 148946.0 169336.0 155471.0 154401.0 150209.0 128881.0 129493.0 True False 151159.25791978775 164013.3557933373 150903.85784727434 159899.98570929075 159375.98940738526 148821.86775060225 162395.12829010474 157188.25850491415 114365.06460290364 151875.6925114235 0.9952827567085375 1.0799184061728697 0.9936011178083942 1.0528346114192282 1.0493844457393842 0.9798926035475259 1.069263458850665 1.0349796988948121 0.7530175679317581 1.0 17.212531461463172 -8.224948824255398 24.671327370442842 0.8765087859617773 1.033012226714257 0.4882668539059838 0.06362216284867407 314.8643450080851 212880.90976895284 0.03859829388321158 0.01458785877016958 5.957323384108227e-09 8.224948824255398 0.15650344075247968 EAS(ph)SSEEPR ddPTM_PC-9_AZD4547_30min_R2 1 EASSSEEPR 9 0 P30414 P30414 NKTR NK-tumor recognition protein;Putative peptidyl-prolyl cis-trans isomerase 1 EAS(0.986)S(0.014)SEEPR 112.83 0.0021416 3271200.0 16267.0 12078.0 16234.0 23112.0 18924.0 14750.0 15243.0 15439.0 15486.0 14855.0 True False 21439.56762538065 15981.977301836949 16018.72655289284 17783.88547684046 16296.72925201743 13827.680168276076 16599.59747039624 13053.25730292571 16304.558344704401 14334.930971510097 1.4956170816581282 1.1148974022686449 1.1174610177564996 1.240597915133667 1.136854393258419 0.9646143532715885 1.1579823790841437 0.910590872664009 1.1374005481511444 1.0 13.807247336984542 -2.0556072635449945 1.0899734914532073 1.074857679397963 199.9999999996704 0.6215009223005914 0.0952131716630592 524.8785643824615 1.7276599135256154 0.029601262995130693 259665.19457243904 0.008798177844275805 2.0556072635449945 198.92514232027244 EAS(ph)SSEEPR ddPTM_PC-9_Lapatinib_30min_R1 2 EASSSEEPR 9 0 P30414 P30414 NKTR NK-tumor recognition protein;Putative peptidyl-prolyl cis-trans isomerase 1 EAS(0.996)S(0.002)S(0.002)EEPR;EAS(0.583)S(0.209)S(0.209)EEPR 102.06 0.0032981 5354900.0 13757.3 19495.6 22526.0 22038.6 25074.0 20245.6 20528.9 21990.0 26310.0 19933.3 True False 13561.118379220154 19450.459136006084 20673.99923287456 23659.39216261442 23599.1966173807 19379.742882798684 21591.785993320864 23011.7356784418 23346.690743417537 23378.744345547297 0.5800618792344593 0.8319719335016642 0.8843075114430652 1.012004400788983 1.0094296027440581 0.8289471237786874 0.9235648276992782 0.9843016091163427 0.9986289425276228 1.0 14.512909825454136 -4.540928371884409 1.3067211289311156 0.957581651011217 0.2244978676579148 0.8137817267830305 0.055247544197412096 1.0139336067616316 1.0216948588434651 0.017320835908530934 1.1530631800113769 2.8778730227079367e-05 4.540928371884409 -0.7330837833533022 EASAS(ph)PDPAK ddPTM_PC-9_Lapatinib_30min_R1 2 EASASPDPAK 10 0 F8WAI8;Q9NUA8 F8WAI8 ZBTB40 Zinc finger and BTB domain-containing protein 40 1 EAS(0.259)AS(0.741)PDPAK;EAS(0.019)AS(0.981)PDPAK 100.55 0.003943 6249300.0 69233.0 84615.0 85715.0 68032.0 75851.0 79355.0 79080.0 75154.0 75268.0 57780.0 True False 68245.7247242229 84419.07916623018 78667.84356946823 73035.30022809893 71389.59330880373 75961.17163554001 83174.37545858831 78645.92920316593 66790.52523282211 67767.19601298959 1.0070613621248485 1.2457218851145733 1.160854339530135 1.077738264603711 1.053453551407377 1.1209135998629751 1.2273545365909118 1.160530962327128 0.9855878531556733 1.0 16.048299458189973 -8.266007031697184 24.795804273424427 0.9927938988313537 1.1348973903756148 0.38734388979643797 0.06978750212792978 377.5143788186678 2049318.921117553 0.06135022892253059 0.01795147380642779 5.419921148922865e-09 8.266007031697184 0.14210349154426105 EASDGEVRR ddPTM_PC-9_Lapatinib_30min_R1 1 EASDGEVRR 9 1 Q8WXX5 Q8WXX5 DNAJC9 DnaJ homolog subfamily C member 9 0 61.765 0.040802 1767600.0 19062.0 20920.0 24721.0 18924.0 27629.0 19915.0 21546.0 24133.0 35046.0 23696.0 False True 18790.172384457324 20871.561025320967 22688.534805819592 20315.734088613404 26003.91654070397 19063.281874132444 22661.54645461234 25254.30728184792 31098.750429259253 27791.8220270647 0.676104372219956 0.7509964983582391 0.8163744997979859 0.7309968403233582 0.9356679283344719 0.6859313453996617 0.8154034101306381 0.9086956320191726 1.1189892623439421 1.0 14.76237280002684 -7.954614623380987 2.592706000168144 1.0568758487739636 0.7736072292171315 0.6968158331926286 0.07564156292840421 0.15651656960978255 2.0283026458803475 0.05490762749159675 0.02021275655757754 1.1101594921710142e-08 7.954614623380987 -0.283268619556832 EASPS(ph)TLNDK ddPTM_PC-9_AZD4547_30min_R2 1 EASPSTLNDK 10 0 P54253 P54253 ATXN1 Ataxin-1 1 EAS(0.131)PS(0.776)T(0.093)LNDK 93.839 0.0065372 18607000.0 40604.0 47788.0 44350.0 64562.0 54933.0 54431.0 46701.0 43295.0 48257.0 51758.0 True False 53515.22738433368 63234.53645472629 43761.89002222479 49678.22837295663 47306.50116260162 51027.42096538543 50857.298528175204 36604.752570125536 50807.76650138195 49945.96817390911 1.0714624090976994 1.2660588785574667 0.8761846375637028 0.9946394111328422 0.9471535519720629 1.0216524542623893 1.0182463247302143 0.7328870358998709 1.017254612513909 1.0 15.608080602506613 -5.265495407946578 24.99665473341585 0.9478083147681721 1.1687606470037204 0.4560117909456256 0.09508408518913554 266.91827953707116 1644984.653833131 0.024186671261848643 0.05343302517251417 5.426309888583163e-06 5.265495407946578 0.22095233223554833 EASPS(ph)TLNDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EASPSTLNDK 10 0 P54253 P54253 ATXN1 Ataxin-1 1 EAS(0.205)PS(0.752)T(0.043)LNDK;EAS(0.16)PS(0.597)T(0.244)LNDK 110.98 0.0016618 20472000.0 87403.0 96638.0 95741.0 116395.0 106952.0 101871.0 113078.0 86847.0 87411.0 72019.0 True False 102198.60161206138 106231.58198170751 98023.82853976433 109873.76550768127 85995.5233613561 96528.70542635387 102366.43322617559 84567.35827200282 88689.22050963475 85075.47459790947 1.201269838282779 1.2486745737686182 1.1521984332506214 1.2914857780926343 1.0108145005102238 1.1346243542287078 1.2032425761947028 0.9940274641039836 1.0424769409610095 1.0 16.376455673910648 -7.071422977643779 0.4056662524454187 0.9885003079110743 1.2476566938659073 0.5006092786749774 0.07355149329662763 1.095642673229902 0.4046168652914073 0.07909612995080585 0.1040945266418386 8.483538251113512e-08 7.071422977643779 0.2591563859548329 EASQT(ph)SSSPAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EASQTSSSPAPK 12 0 Q5T8J1;P30281-4;P30281-2;P30281-3;P30281 Q5T8J1 CCND3 G1/S-specific cyclin-D3 1 EAS(0.026)QT(0.46)S(0.46)S(0.036)S(0.018)PAPK;EAS(0.045)QT(0.406)S(0.406)S(0.031)S(0.112)PAPK 121.42 0.0010947 41403000.0 155793.0 162784.0 168925.0 200398.0 232633.0 204630.0 208474.0 202363.0 186324.0 153558.0 True False 182165.67784799007 178944.11971802247 172952.81265162968 189170.34975908176 187050.2336199639 193898.84256947302 188725.83349894485 197051.18567132222 189048.6360096231 181396.8498355407 1.0042383757664282 0.9864786509813046 0.9534499237910327 1.0428535552331186 1.0311658322046315 1.0689206716945028 1.04040303715334 1.0862988296101843 1.042182574730596 1.0 17.46878987646584 -5.835301585820787 7.4861959961834375 1.0487653777862993 0.9820703330119095 0.5806164398794775 0.024430508509889693 0.1464925576548908 12.588727565172396 0.006716865735940802 0.010035897929735742 1.4611621515962006e-06 5.835301585820787 -0.06669504477438981 EASQTS(ph)SSPAPK ddPTM_PC-9_AZD4547_30min_R2 1 EASQTSSSPAPK 12 0 Q5T8J1;P30281-4;P30281-2;P30281-3;P30281 Q5T8J1 CCND3 G1/S-specific cyclin-D3 1 EASQT(0.033)S(0.649)S(0.075)S(0.242)PAPK 132.06 9.8286e-05 25842000.0 71548.0 64818.0 84688.0 99960.0 96955.0 77273.0 82976.0 86898.0 75565.0 92650.0 True False 94298.7757091496 85769.15091492524 83564.98178584373 76915.76636660493 83494.47181512101 72441.10709445406 90360.70325418851 73469.91081738683 79559.2116309949 89406.35170046515 1.054721212929875 0.959318317811183 0.9346649337153187 0.8602942062135924 0.9338762876137648 0.8102456449308083 1.010674314918035 0.8217526989976104 0.889860844535288 1.0 16.448089708063755 -4.713528385249441 1.3675701903798023 0.8986462008394032 1.1374770330926998 0.33596318136940106 0.06329310371586411 1.5603782075064285 2.3365916413366854 0.01720664253862051 0.5418696771458017 1.9340674448993935e-05 4.713528385249441 0.2388308322532966 EASQTSSS(ph)PAPK ddPTM_PC-9_AZD4547_30min_R2 1 EASQTSSSPAPK 12 0 Q5T8J1;P30281-4;P30281-2;P30281-3;P30281 Q5T8J1 CCND3 G1/S-specific cyclin-D3 1 EAS(0.002)QT(0.024)S(0.077)S(0.077)S(0.82)PAPK 109.95 0.0012506 24848000.0 36045.0 32598.0 43609.0 55852.0 48501.0 45931.0 37831.0 47113.0 44157.0 46537.0 True False 47506.56021742459 43134.66601136621 43030.7161663856 42976.1843047981 41767.47333820002 43058.92730909077 41197.88571164206 39832.76839903744 46491.04887169782 44907.753794760385 1.057869882215472 0.9605171126683906 0.9582023710882243 0.9569880627120645 0.9300726446726276 0.9588305731317757 0.9173891417488093 0.8869908876111486 1.0352566081165735 1.0 15.454676942455114 -4.743179601272698 3.5140946499820056 0.949689792551046 1.076301047951037 0.37058438545541295 0.03927864500311511 0.346748293528987 6.5901957383133 0.009512723657953522 0.12361616720041553 1.8064269286986856e-05 4.743179601272698 0.12661125539999107 EASQTSSS(ph)PAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EASQTSSSPAPK 12 0 Q5T8J1;P30281-4;P30281-2;P30281-3;P30281 Q5T8J1 CCND3 G1/S-specific cyclin-D3 1 EASQT(0.001)S(0.033)S(0.09)S(0.876)PAPK 167.22 0.00090835 19410000.0 42873.0 48015.0 47262.0 50505.0 58690.0 55162.0 50954.0 56387.0 52268.0 39502.0 True False 50130.55211965168 52781.611879919736 48388.90532213311 47675.36858941925 47190.115809690185 52269.20761284886 46127.26824498611 54906.90099696497 53032.320618658894 46663.39990234007 1.0743013201902962 1.1311137206115334 1.0369777046551318 1.0216865613992356 1.0112875595960102 1.120132860491112 0.9885106602074429 1.1766588185146687 1.1364864268280512 1.0 15.51000380567891 -7.766577922579482 24.999928846922305 1.1174294398269995 1.0566626771922214 0.11406633554899293 0.05988150623926019 229.5477395904955 1116761.7193849783 0.030785945446828864 0.015491190677010906 1.7116780341083012e-08 7.766577922579482 -0.06076676263477809 EASQTSSS(ph)PAPK ddPTM_PC-9_Lapatinib_30min_R1 3 EASQTSSSPAPK 12 0 Q5T8J1;P30281-4;P30281-2;P30281-3;P30281 Q5T8J1 CCND3 G1/S-specific cyclin-D3 1 EAS(0.017)QT(0.122)S(0.252)S(0.072)S(0.536)PAPK;EAS(0.001)QT(0.024)S(0.201)S(0.024)S(0.75)PAPK;EAS(0.007)QT(0.082)S(0.33)S(0.082)S(0.499)PAPK 120.59 0.00048587 55273000.0 302843.0 299840.0 312544.0 314404.0 323983.0 288314.0 278631.0 271917.0 313077.0 252051.0 True False 298524.40328539535 299145.7389021152 286847.83877472946 337526.3189809977 304926.95691508526 275983.4823127605 293057.14982804673 284551.25650181196 277814.9714130346 295617.6795131541 1.0098327129048177 1.0119345344797084 0.9703338421678045 1.141766350161675 1.031490935918523 0.9335824662695117 0.991338374317381 0.962565083963966 0.9397779316533491 1.0 18.173373027355368 -6.741419849072795 23.195315667313512 0.9647309716063807 1.0344506193399783 0.36001173984170254 0.04505422961582957 120.50262269119074 139617.4472823387 0.0153264141389536 0.015300156272661692 1.813761382501114e-07 6.741419849072795 0.06971964773359762 EASRPPEEPSAPS(ph)PTLPAQFK ddPTM_PC-9_AZD4547_30min_R2 2 EASRPPEEPSAPSPTLPAQFK 21 1 H0Y3X6;A0A0C4DFX9;Q9H3P2;Q9H3P2-7 H0Y3X6 NELFA Negative elongation factor A 1 EASRPPEEPS(0.001)APS(0.786)PT(0.213)LPAQFK;EASRPPEEPSAPS(0.997)PT(0.002)LPAQFK 108.97 2.3459e-05 252200000.0 543910.0 509380.0 704080.0 894000.0 785650.0 715800.0 559040.0 792520.0 602240.0 723030.0 True False 716862.0659691886 674027.1235311894 694743.4391623003 687902.1121623132 676576.0588061457 671040.9128442047 608793.4769960186 670054.2442978614 634073.1769026717 697716.9397732057 1.0274396751814656 0.9660466660739 0.9957382421990902 0.9859329377697454 0.9696999173132705 0.9617666916075277 0.872550804333213 0.9603525528786271 0.9087828326323545 1.0 19.412282335497807 -6.7625190305115375 2.3149460257072008 0.9314631947637568 0.9906121277575789 0.34336403462423915 0.03463528191706378 0.30838560605723514 3.3925945044255226 0.012634360709456883 0.011657389602200122 1.7277502699169717e-07 6.7625190305115375 0.05914893299382207 EASRPPEEPSAPS(ph)PTLPAQFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EASRPPEEPSAPSPTLPAQFK 21 1 H0Y3X6;A0A0C4DFX9;Q9H3P2;Q9H3P2-7 H0Y3X6 NELFA Negative elongation factor A 1 EASRPPEEPSAPS(0.997)PT(0.003)LPAQFK;EASRPPEEPSAPS(0.746)PT(0.254)LPAQFK;EASRPPEEPS(0.002)APS(0.73)PT(0.268)LPAQFK;EASRPPEEPSAPS(0.999)PT(0.001)LPAQFK 141.29 6.7423e-07 183448000.0 339366.0 291108.0 321046.0 375013.0 466066.0 411150.0 397406.0 439791.0 379649.0 307884.0 True False 396813.9610159704 320007.2783742512 328700.9542137352 354002.2374185498 374743.71298277524 389588.57021179143 359760.826709717 428246.9522470824 385200.64839965606 363700.93199159723 1.0910446636555173 0.8798637842963913 0.9037671485024661 0.9733333249383272 1.0303622565130879 1.0711783664628947 0.989166634079532 1.1774700435933345 1.059113723713404 1.0 18.47239309717269 -6.340552062137492 2.39325250448728 1.0659738015253075 0.949231889889744 0.29319505889706 0.07069841689507211 0.34045258414794055 3.8230677066548644 0.023818308390825018 0.02872338995176379 4.5650752194072057e-07 6.340552062137492 -0.11674191163556347 EASRPPEEPSAPS(ph)PTLPAQFK ddPTM_PC-9_Lapatinib_30min_R1 3 EASRPPEEPSAPSPTLPAQFK 21 1 H0Y3X6;A0A0C4DFX9;Q9H3P2;Q9H3P2-7 H0Y3X6 NELFA Negative elongation factor A 1 EASRPPEEPS(0.002)APS(0.797)PT(0.2)LPAQFK;EASRPPEEPS(0.004)APS(0.983)PT(0.013)LPAQFK;EASRPPEEPS(0.001)APS(0.915)PT(0.084)LPAQFK 109.28 2.2046e-05 111889500.0 253166.0 230357.0 286301.0 235178.0 238102.0 275056.0 261778.0 208902.0 256523.0 195046.0 True False 249555.8064150419 229823.6225195923 262762.43693382014 252473.77465080924 224097.30848654278 263292.4960668524 275331.58395040856 218608.34955424487 227630.6784330555 228759.44121754123 1.0909093197938184 1.0046519666964873 1.1486408409432307 1.1036649386230866 0.9796199330345237 1.1509579437050277 1.2035856639839362 0.9556254744754203 0.99506572153491 1.0 17.80347176107567 -7.795263871422842 24.999748278440666 0.9815090900939348 1.0936011513383992 0.4002752759812064 0.06373669979021672 208.0845028320368 153792.9689447317 0.03605670438614022 0.017322503643489074 1.602271576455359e-08 7.795263871422842 0.11209206124446436 EASRPPEEPSAPSPT(ph)LPAQFK ddPTM_PC-9_Lapatinib_30min_R1 1 EASRPPEEPSAPSPTLPAQFK 21 1 H0Y3X6;A0A0C4DFX9;Q9H3P2;Q9H3P2-7 H0Y3X6 NELFA Negative elongation factor A 1 EASRPPEEPS(0.003)APS(0.392)PT(0.605)LPAQFK 85.11 0.00033275 86143000.0 125380.0 108270.0 127110.0 114910.0 113440.0 153470.0 118620.0 133120.0 165480.0 99556.0 True False 123592.05820812422 108019.30746708873 116659.50645878902 123360.86472852308 106767.68223162102 146906.44585604363 124761.5631878823 139305.24117845256 146841.8998183479 116764.12194996871 1.0584763208434964 0.9251070077277078 0.9991040442095346 1.0564963164060015 0.9143877455556855 1.2581471380308957 1.0684922825980772 1.1930483341290599 1.2575943480418323 1.0 16.83323752060386 -6.757507501557784 24.9999792198674 1.162086683764913 0.9911900924450611 0.4793335629463541 0.0857091374471417 83.86291202773164 533224.2900754517 0.027372880076944987 0.026411462214054784 1.7478030723984856e-07 6.757507501557784 -0.17089659131985202 EASSS(ph)SPEAGEGQIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EASSSSPEAGEGQIR 15 0 J3QSS7;Q86U28-2;Q86U28 J3QSS7 ISCA2 Iron-sulfur cluster assembly 2 homolog, mitochondrial 1 EAS(0.015)S(0.073)S(0.526)S(0.386)PEAGEGQIR;EAS(0.002)S(0.135)S(0.432)S(0.432)PEAGEGQIR 173.33 3.1382e-05 10146900.0 48326.0 70686.0 82972.0 74356.0 89964.0 87115.0 73039.0 69988.0 72804.0 67095.0 True False 56506.63731799237 77703.23893250062 84950.36715306238 70190.07438540469 72336.20001197758 82546.5360428072 66120.21716343243 68150.88915841558 73868.6207683639 79258.79237627222 0.7129384087727889 0.9803737428096712 1.0718100113078943 0.8855809214476192 0.9126583668922129 1.041481122383581 0.8342319530877297 0.8598527319830572 0.9319927613542345 1.0 16.274283365451915 -4.7556463297693226 24.976266112402744 0.9424862530273624 0.7129380344485996 0.47513003352995276 0.07352091572077103 178.06283492590853 767624.8285947279 0.019114949697898204 0.1661891756736631 1.7553093663257607e-05 4.7556463297693226 -0.22954821857876284 EASSSS(ph)PEAGEGQIR ddPTM_PC-9_AZD4547_30min_R2 1 EASSSSPEAGEGQIR 15 0 J3QSS7;Q86U28-2;Q86U28 J3QSS7 ISCA2 Iron-sulfur cluster assembly 2 homolog, mitochondrial 1 EAS(0.003)S(0.003)S(0.113)S(0.881)PEAGEGQIR 192.32 4.3853e-08 5937000.0 11836.0 12414.0 22183.0 26622.0 24112.0 20913.0 18392.0 25816.0 17090.0 18502.0 True False 15599.60179590616 16426.582730998845 21888.838925885295 20484.709205799885 20764.465003415986 19605.30680401068 20028.85236997491 21826.730392663387 17993.342510073508 17854.25061157051 0.8737192131601862 0.9200376475254324 1.225973545576881 1.1473295436171762 1.1629984061027743 1.0980750315728958 1.1217974254822625 1.222494904295703 1.0077904080954738 1.0 14.123979961154207 -5.161069271966589 5.8513615018203105 1.1322100930715413 0.8875025877987204 0.6072567147682938 0.07276748422751023 0.13205470792295693 6.3009188886657155 0.01745141557579909 0.048053091025882975 6.901297161980378e-06 5.161069271966589 -0.24470750527282092 EASSSS(ph)PEAGEGQIR ddPTM_PC-9_Lapatinib_30min_R1 2 EASSSSPEAGEGQIR 15 0 J3QSS7;Q86U28-2;Q86U28 J3QSS7 ISCA2 Iron-sulfur cluster assembly 2 homolog, mitochondrial 1 EASS(0.001)S(0.205)S(0.794)PEAGEGQIR;EASSS(0.006)S(0.994)PEAGEGQIR 214.65 1.1827e-17 11612900.0 33326.0 35354.0 38710.0 34731.0 43929.0 36691.0 45273.0 45728.0 46045.0 34706.0 True False 32850.765128760104 35272.13998514327 35527.413224921176 37285.233599219624 41345.18258773695 35121.8114608985 47617.01441750972 47852.68981827133 40858.92722465449 40704.88585716189 0.8070472238648992 0.866533322533252 0.8728046394624699 0.9159891451374604 1.0157302180583907 0.8628401903433647 1.1698107835163396 1.1756006388567677 1.003784345889905 1.0 15.31291435288232 -6.538525884244793 0.8633149919755749 1.0902389762556277 0.8404506012581214 0.555033914091738 0.08099333678951684 0.44299882461351453 0.7270367581340402 0.047754753884067774 0.057068547874291414 2.893837337263011e-07 6.538525884244793 -0.24978837499750628 EASTTAAAPGEETS(ph)PVQVPAR ddPTM_PC-9_AZD4547_30min_R2 2 EASTTAAAPGEETSPVQVPAR 21 0 Q5SXM2 Q5SXM2 SNAPC4 snRNA-activating protein complex subunit 4 1 EASTTAAAPGEET(0.249)S(0.751)PVQVPAR;EASTTAAAPGEET(0.227)S(0.773)PVQVPAR 148.85 3.6744e-06 14624600.0 56031.0 50248.0 68457.0 95261.0 74982.0 67991.0 57181.0 85355.0 56948.0 71892.0 True False 73847.69248279964 66489.68334680446 67549.21545099081 73300.0482177786 64572.0435835326 63739.51202178028 62269.99822572505 72165.34601277449 59958.155018353784 69375.0829622217 1.0644699700469333 0.9584087039292121 0.9736812205006635 1.0565760080992517 0.9307670827391356 0.918766642145707 0.8975844866323874 1.040219959838783 0.8642606604305481 1.0 16.08212997114805 -6.286232367649357 24.8339288792946 0.9405683736711303 1.0065355506083327 0.2797443401754385 0.05564212993001955 995.6038481878971 997244.8799792366 0.016648279279692684 0.018886779126262115 5.173299624133948e-07 6.286232367649357 0.06596717693720233 EASTTAAAPGEETS(ph)PVQVPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EASTTAAAPGEETSPVQVPAR 21 0 Q5SXM2 Q5SXM2 SNAPC4 snRNA-activating protein complex subunit 4 1 EASTTAAAPGEET(0.152)S(0.847)PVQVPAR;EASTTAAAPGEET(0.102)S(0.898)PVQVPAR 223.76 5.925499999999999e-41 10083100.0 49983.0 49129.0 58674.0 60268.0 66227.0 55002.0 63007.0 56324.0 52580.0 45396.0 True False 58444.13469075059 54006.20243775024 60073.010682384134 56891.379351492316 53250.2947644974 52117.598294512805 57038.52082882289 54845.55468021098 53348.883028412856 53625.935445461706 1.0898483020438694 1.007091102264785 1.1202230820472903 1.0608929966238372 0.9929951677701484 0.9718729913348942 1.0636368457727292 1.0227430854980544 0.9948336114839318 1.0 15.71064328860933 -6.184488818990339 6.112953952346242 1.0099129668359372 1.0693733159603218 0.43283396789277273 0.03468520597016286 0.24771106427454462 15.705849575400453 0.010395131787765398 0.01346694317553735 6.538997645853683e-07 6.184488818990339 0.05946034912438458 EASTTAAAPGEETS(ph)PVQVPAR ddPTM_PC-9_Lapatinib_30min_R1 2 EASTTAAAPGEETSPVQVPAR 21 0 Q5SXM2 Q5SXM2 SNAPC4 snRNA-activating protein complex subunit 4 1 EASTTAAAPGEET(0.09)S(0.91)PVQVPAR;EASTTAAAPGEET(0.015)S(0.985)PVQVPAR 170.22 9.8714e-09 12170200.0 63323.0 52697.0 67884.0 54880.0 58975.0 52992.0 49732.0 51552.0 64638.0 44917.0 True False 62420.00240798398 52574.983334194054 62302.83955981789 58916.05827431322 55506.206449311125 50725.655690385414 52306.87961945511 53947.29411982862 57357.78777168465 52680.84360185965 1.1848709728289266 0.9979905358299567 1.1826469604525958 1.118358292049702 1.0536316933116032 0.962886169282885 0.9929013288923236 1.02404005766385 1.0887788397082523 1.0 15.684990827848408 -6.422397457294983 3.8532304769144794 1.0133927542899086 1.116080429651733 0.43986952072747476 0.05678983564711186 0.23757081225800905 6.33886483984639 0.01817985864975399 0.02049185244603996 3.7809640035360475e-07 6.422397457294983 0.10268767536182444 EAT(ph)GLSPQAAQEK ddPTM_PC-9_AZD4547_30min_R2 1 EATGLSPQAAQEK 13 0 P17029;C9JRM9 P17029 ZKSCAN1 Zinc finger protein with KRAB and SCAN domains 1 1 EAT(0.522)GLS(0.478)PQAAQEK 174.59 0.00043333 51401000.0 37890.0 46048.0 52597.0 59312.0 53182.0 54128.0 49624.0 57707.0 46967.0 44472.0 True False 49938.231839040585 60932.11548228086 51899.52941373074 45638.534761265204 45798.59728814157 50743.36760328461 54040.43986557386 48789.70912493905 49449.57973496912 42915.0488162233 1.1636531523683666 1.4198309721890965 1.2093550128762993 1.0634622590482137 1.0671920119272518 1.1824143046087354 1.2592421855790783 1.136890449172574 1.1522666546816451 1.0 15.389196019010187 -2.622095316059069 0.021139272619698186 3.3348433329217733e-06 2.6138606691153847 0.29120473263165325 0.09380463941972879 3269.01942132805 6.455160825747278 307.0723234162504 514.9601422076598 0.002387287279507914 2.622095316059069 2.6138573342720517 EAT(ph)GLSPQAAQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EATGLSPQAAQEK 13 0 P17029;C9JRM9 P17029 ZKSCAN1 Zinc finger protein with KRAB and SCAN domains 1 1 EAT(0.932)GLS(0.068)PQAAQEK 170.74 0.00057071 39157000.0 45728.0 49105.0 41682.0 48143.0 52323.0 37694.0 45918.0 30282.0 34848.0 32384.0 True False 53468.84723083132 53979.819876360736 42675.85695986528 45445.703791711916 42070.68375379828 35717.260283505406 41568.31462246877 29487.12958643114 35357.58607406108 38254.96284839706 1.3976970110447184 1.411054039975955 1.1155639368671735 1.187968838757248 1.0997444676792074 0.9336634419186741 1.086612338043626 0.7708053384677825 0.9242614145040953 1.0 15.223359301533108 -5.440075656311339 0.5177008317800881 0.9025736125980233 1.594884543687576 0.7804125594504734 0.09012899374897389 1.0297020995024821 0.3422821475219527 0.06054263936319553 0.4007752234919725 3.630148102321143e-06 5.440075656311339 0.6923109310895528 EAT(ph)GLSPQAAQEK ddPTM_PC-9_Lapatinib_30min_R1 1 EATGLSPQAAQEK 13 0 P17029;C9JRM9 P17029 ZKSCAN1 Zinc finger protein with KRAB and SCAN domains 1 1 EAT(0.98)GLS(0.02)PQAAQEK 211.75 3.2261999999999997e-10 5914000.0 24202.0 24381.0 24360.0 21428.0 24732.0 29871.0 24248.0 24564.0 25538.0 22059.0 True False 23856.87504189676 24324.54729246416 22357.214832319292 23003.886601712537 23277.31238498282 28593.486962701994 25503.442793624778 25705.333115290785 22661.641512937935 25871.868758230088 0.9221164216948056 0.9401928990817987 0.8641515246248784 0.8891466950718347 0.8997151540349432 1.1051960424623803 0.9857595920863618 0.9935630609255341 0.8759182309058773 1.0 14.659096645047144 -6.629184638464978 20.13208871962118 0.9925471792774946 0.9021248257111237 0.3987285256475971 0.05464735526902537 2.887099573970815 534.2313178349333 0.01833912892291305 0.018339083627042882 2.3486340966936223e-07 6.629184638464978 -0.09042235356637085 EAT(ph)SDPSRTPEEEPLNLEGLVAHR ddPTM_PC-9_Lapatinib_30min_R1 1 EATSDPSRTPEEEPLNLEGLVAHR 24 1 A0A087WWW7;E9PGF5;E9PF55;A0A494C067;A0A2R8Y4T1;Q9HBL0 A0A087WWW7 TNS1 Tensin-1 1 EAT(0.273)S(0.273)DPS(0.227)RT(0.227)PEEEPLNLEGLVAHR 91.27600000000001 7.0824e-06 2947000.0 10479.0 8322.7 10411.0 8167.6 14191.0 11087.0 7375.0 9774.8 9661.5 8267.7 True False 10329.567538386747 8303.429299495168 9555.04776762218 8768.272550314878 13356.313280579472 10612.834855059325 7756.841413847854 10228.972892661794 8573.320129894657 9696.760928982225 1.0652595865814485 0.8563095821695894 0.9853855155966066 0.9042475744769339 1.3773994613664622 1.094472157536553 0.7999414929024155 1.054885540396161 0.8841426732786858 1.0 13.243287199788432 -7.217774749046672 24.951036530035246 0.9393158379803044 1.0442074427888688 0.12478266890047263 0.14555043620541866 1138.9688821335474 650835.3489247664 0.058863776061161985 0.045595414625106655 6.056549219764101e-08 7.217774749046672 0.10489160480856441 EATAQKPTGSVGSTVT(ph)TPPPLVR ddPTM_PC-9_AZD4547_30min_R2 2 EATAQKPTGSVGSTVTTPPPLVR 23 1 Q86YP4-2;Q86YP4;Q86YP4-3 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 1 EATAQKPT(0.003)GS(0.001)VGS(0.033)T(0.139)VT(0.626)T(0.2)PPPLVR;EATAQKPTGSVGST(0.001)VT(0.499)T(0.499)PPPLVR 70.02 0.00076891 184517000.0 31662.0 30905.0 37838.0 57170.0 46194.0 44170.0 42035.0 45584.0 34833.0 45146.0 True False 41729.857389488054 40894.43686978566 37336.24339708998 43990.33976769512 39780.76046648135 41408.04291747487 45776.03356741492 38540.040216112786 36674.20126702111 43565.45228137295 0.9578658134884157 0.9386895975660668 0.8570149382577085 1.009752853788318 0.913126304980201 0.950478894377954 1.0507416122243987 0.8846468519871455 0.8418184443525611 1.0 15.410896900341143 -4.7661467257363865 7.872151706478124 0.9376233829308178 0.9581055186191704 0.008016287994273674 0.06413893704989726 0.7858824921680004 411.2946908892224 0.01601783516155689 0.08674633296367189 1.7133783474203002e-05 4.7661467257363865 0.020482135688352554 EATAQKPTGSVGSTVT(ph)TPPPLVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EATAQKPTGSVGSTVTTPPPLVR 23 1 Q86YP4-2;Q86YP4;Q86YP4-3 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 1 EATAQKPTGSVGS(0.002)T(0.005)VT(0.496)T(0.496)PPPLVR;EATAQKPTGSVGS(0.003)T(0.009)VT(0.494)T(0.494)PPPLVR 63.488 0.0018054000000000002 90990900.0 57368.0 60758.0 66905.0 75599.0 84018.0 66676.0 85891.0 83809.0 75980.0 63278.0 True False 67079.26933035198 66789.65270436664 68500.26893862535 71363.43312526484 67555.27602825935 63179.39318361037 77754.7826830104 81609.10255297575 77091.06375996205 74749.80049162752 0.8973839246282043 0.8935094443743369 0.9163940035705893 0.9546973056236855 0.9037519242051488 0.8452115292359461 1.040200537949522 1.0917634831964067 1.031321331333811 1.0 16.189782108289975 -7.304393822295108 10.484171738497658 1.0486084844636192 0.9046182209011662 0.8080492642203737 0.033084925734806696 0.32405975903447287 78.04700293003192 0.0141240948118295 0.009536880153106784 4.961422110051144e-08 7.304393822295108 -0.14399026356245304 EATAQKPTGSVGSTVT(ph)TPPPLVR ddPTM_PC-9_Lapatinib_30min_R1 3 EATAQKPTGSVGSTVTTPPPLVR 23 1 Q86YP4-2;Q86YP4;Q86YP4-3 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 1 EATAQKPTGSVGS(0.002)T(0.018)VT(0.49)T(0.49)PPPLVR;EATAQKPTGSVGS(0.002)T(0.01)VT(0.494)T(0.494)PPPLVR;EATAQKPTGSVGS(0.005)T(0.022)VT(0.486)T(0.486)PPPLVR 80.382 0.00013273 197262900.0 144414.0 107892.0 124713.0 113372.0 113344.0 121191.0 115635.0 100704.0 118480.0 98516.0 True False 142354.62987771563 107642.1827028645 114459.57854610152 121709.75507790543 106677.32876287779 116007.94344001937 121622.01449359956 105383.07547802666 105135.53475028914 115544.35933568141 1.2320344385150346 0.9316091527249776 0.9906115642873715 1.0533595562576292 0.9232586460837697 1.0040121742593349 1.0526001891642434 0.9120572919692772 0.9099149050179735 1.0 16.818087306227888 -4.755167427224423 24.999789944239126 0.9771303035197151 1.2320348598151951 0.6898652544319394 0.05163405837400553 124.06945722118233 494489.7290874298 0.013139819598652422 0.11944469137678836 1.7572460378951907e-05 4.755167427224423 0.25490455629548003 EATAQKPTGSVGSTVTT(ph)PPPLVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EATAQKPTGSVGSTVTTPPPLVR 23 1 Q86YP4-2;Q86YP4;Q86YP4-3 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 1 EATAQKPTGSVGS(0.008)T(0.008)VT(0.164)T(0.821)PPPLVR 95.988 6.5905e-06 83751000.0 21422.0 20268.0 24113.0 21898.0 23650.0 28145.0 26950.0 26260.0 23056.0 22509.0 True False 25048.3214962139 22280.07309345441 24687.945369061745 20671.126054273886 19015.952272945524 26669.026653559173 24397.10089889659 25570.702824769913 23393.15038233336 26589.703518854047 0.9420308683943318 0.8379210801525564 0.9284776474305622 0.777410926737733 0.715162252917255 1.002983227498151 0.9175394107571474 0.96167686889169 0.8797822948926791 1.0 14.69858007046208 -6.789559996470214 24.999999833788966 0.9478225957901446 0.8414897370194223 0.3889771927678427 0.07018306046353144 252.66187943844585 224621.57192449164 0.025452248716759572 0.022451120237886396 1.6234540597180675e-07 6.789559996470214 -0.1063328587707223 EATDAIGHLDR ddPTM_PC-9_AZD4547_30min_R2 2 EATDAIGHLDR 11 0 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 0 ; 110.64 0.0016044 21399800.0 211482.0 204979.0 275800.0 319260.0 264480.0 269180.0 231750.0 313580.0 242230.0 252180.0 False True 278728.8769011344 271234.45316718327 272142.7117954815 245659.53951783016 227761.51725711153 252348.13204722397 252375.30104076117 265123.4163515409 255033.78327765368 243351.25495761784 1.1453767803649828 1.1145800469137568 1.1183123417336722 1.0094854023276532 0.9359373030427912 1.0369707445773109 1.0370823897526846 1.0894680464981161 1.0480068546269485 1.0 17.892680689022257 -5.7429959672173725 10.208263434289844 1.0237577070000892 1.1250762672767287 0.611878634928513 0.03782342555672147 0.24843538651816024 129.9147166166165 0.011584387804689653 0.019582952998815663 1.8071909071918108e-06 5.7429959672173725 0.10131856027663955 EATDAIGHLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EATDAIGHLDR 11 0 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 0 ; 120.03 0.00076065 22616000.0 136414.0 160605.0 164692.0 173177.0 190265.0 158241.0 177711.0 134089.0 142277.0 134130.0 False True 159506.19590068748 176548.80299853216 168618.8818778883 163474.4541374093 152983.93907873105 149942.5633926403 160876.92756377804 130569.30582903912 144357.5319633607 158446.70722750446 1.0066867194132458 1.1142472196978883 1.0641993439205917 1.0317314698290687 0.965522993539211 0.9463280494516458 1.015337777469772 0.8240581840653981 0.9110794063778559 1.0 17.27363815298996 -6.382269627466224 1.1051448081130002 0.9232279750095067 1.071130834767583 0.49706852752137454 0.054901945503285074 0.3881950825980379 0.9956499186708168 0.024920199790100243 0.03297782517183373 4.146965024439429e-07 6.382269627466224 0.14790285975807627 EATDAIGHLDR ddPTM_PC-9_Lapatinib_30min_R1 4 EATDAIGHLDR 11 0 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 0 ;;; 147.26 0.00021131 35650600.0 362739.0 431591.0 437959.0 363477.0 437797.0 434057.0 401489.0 434694.0 448260.0 360102.0 False True 357566.2753418147 430591.67755637236 401951.70159062976 390208.311103727 412046.64120201906 415493.3939462866 422276.1359192352 454891.47016846726 397772.238412936 422345.1508942463 0.846621003188333 1.019525562551542 0.9517137837135414 0.9239085858509922 0.9756158921904944 0.9837768779079096 0.9998365910562369 1.0770609517010188 0.9418179362796489 1.0 18.688062961427434 -6.741565446256147 1.677560404145112 1.0099653490791058 0.9426756993000288 0.2644143993584872 0.05027564661954156 0.5092036863408909 2.968204379713709 0.020615941847641116 0.01907511434260833 1.8131534210870046e-07 6.741565446256147 -0.06728964977907703 EATGLS(ph)PQAAQEK ddPTM_PC-9_AZD4547_30min_R2 3 EATGLSPQAAQEK 13 0 P17029;C9JRM9 P17029 ZKSCAN1 Zinc finger protein with KRAB and SCAN domains 1 1 EAT(0.03)GLS(0.97)PQAAQEK;EAT(0.019)GLS(0.981)PQAAQEK;EAT(0.001)GLS(0.999)PQAAQEK 201.16 2.7789e-07 58652600.0 77561.0 87452.0 101544.0 99668.0 89396.0 101237.0 94450.0 116072.0 87297.0 92254.0 True False 102223.78463097964 115719.14878293147 100197.46021232916 76691.08245524985 76984.90848728317 94906.63438615376 102855.86702610564 98135.73946921383 91911.34119964234 89024.21553993221 1.1482694232236925 1.2998614824190744 1.1255079261820076 0.8614631647144335 0.8647636827841662 1.0660766153404966 1.155369540773647 1.1023488258112717 1.0324307902316208 1.0 16.441910197510595 -5.525178857929085 24.96515391632689 1.0162648954398439 1.2212202897576665 0.45602480683726065 0.09390958163169126 65.8045127399119 714231.9820177514 0.02872360867177137 0.05016674678553937 2.98415338521054e-06 5.525178857929085 0.20495539431782261 EATGLS(ph)PQAAQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EATGLSPQAAQEK 13 0 P17029;C9JRM9 P17029 ZKSCAN1 Zinc finger protein with KRAB and SCAN domains 1 1 EAT(0.001)GLS(0.999)PQAAQEK;EAT(0.002)GLS(0.998)PQAAQEK;EAT(0.001)GLS(0.999)PQAAQEK;EAT(0.001)GLS(0.999)PQAAQEK 184.87 4.9273e-05 23350300.0 93863.0 112874.0 109697.0 105460.0 124338.0 102157.0 114894.0 89169.0 84849.0 77544.0 True False 109752.15202124587 124079.38476172174 112312.59250818913 99551.41810593332 99974.86146780133 96799.70708287958 104010.40855947408 86828.40823236505 86089.75610646271 91602.11336203395 1.1981399554339813 1.354547184641141 1.2260917176037447 1.0867808007057846 1.0914034381791633 1.0567409804215266 1.1354586127112538 0.9478865175216858 0.9398228157271322 1.0 16.48309326282532 -6.029477876939243 0.5345127315173349 0.9739703935107946 1.3352006544676824 0.7261087351851581 0.06459912185278575 0.7351083290363185 0.3798501603252284 0.05046233225279559 0.1435759759504219 9.343769644224148e-07 6.029477876939243 0.3612302609568878 EATGLS(ph)PQAAQEK ddPTM_PC-9_Lapatinib_30min_R1 3 EATGLSPQAAQEK 13 0 P17029;C9JRM9 P17029 ZKSCAN1 Zinc finger protein with KRAB and SCAN domains 1 1 EATGLS(1)PQAAQEK;EAT(0.001)GLS(0.999)PQAAQEK;EAT(0.416)GLS(0.584)PQAAQEK 150.76 7.5523e-05 92675900.0 138485.0 172872.0 172598.0 146046.0 155501.0 174513.0 163509.0 164389.0 156258.0 135086.0 True False 136510.17850496108 172471.72550522402 158407.65868754697 156786.7100351738 146354.73690672856 167049.48579967243 171974.6959643185 172027.11307154954 138658.578570313 158435.43510921914 0.8616139338453948 1.0885931255613923 0.9998246830221218 0.9895937100629745 0.9237500235085503 1.0543694703430146 1.0854560145952572 1.0857868566647406 0.8751740320890162 1.0 17.273535514014867 -6.790768801916355 24.990021412488357 1.0296001185477532 0.9815631366068931 0.0726675649809091 0.07822883729052635 582.0517061619528 495930.710092291 0.027315537943714784 0.02409359718886209 1.6189416571501807e-07 6.790768801916355 -0.048036981940860146 EATGLS(ph)PQAAQEKDGIVIVK ddPTM_PC-9_AZD4547_30min_R2 2 EATGLSPQAAQEKDGIVIVK 20 1 P17029;C9JRM9 P17029 ZKSCAN1 Zinc finger protein with KRAB and SCAN domains 1 1 EAT(0.07)GLS(0.93)PQAAQEKDGIVIVK;EAT(0.047)GLS(0.953)PQAAQEKDGIVIVK 75.564 0.0010892999999999999 39436000.0 73558.0 56104.0 104119.0 146956.0 142810.0 100728.0 92069.0 89682.0 84841.0 112953.0 True False 96947.91389855233 74238.52082648291 102738.31402985402 113077.564647567 122983.29658003617 94429.46223661765 100262.96263871345 75823.70758734265 89325.52205366561 108998.5498502176 0.8894422359909845 0.6810964084246915 0.9425658797390772 1.0374226519798166 1.1283021356617677 0.8663368674755734 0.919855931812778 0.6956395997152001 0.8195111052065733 1.0 16.73394941551409 -10.178689458013533 9.151522169321314 1.0000118508684497 0.8885805271420086 0.06381579216537847 0.13002113907766616 0.0 0.0 0.13866446599757185 0.033631072931050436 6.626901905160312e-11 10.178689458013533 -0.11143132372644104 EATGLS(ph)PQAAQEKDGIVIVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EATGLSPQAAQEKDGIVIVK 20 1 P17029;C9JRM9 P17029 ZKSCAN1 Zinc finger protein with KRAB and SCAN domains 1 1 EAT(0.074)GLS(0.926)PQAAQEKDGIVIVK;EAT(0.042)GLS(0.958)PQAAQEKDGIVIVK 89.344 0.0003278 33214000.0 57378.0 31371.0 46618.0 79852.0 84778.0 78907.0 77108.0 85291.0 73248.0 62664.0 True False 67090.96213284298 34485.305556283725 47729.549919749494 75378.1513236768 68166.35948396499 74768.97801216543 69803.77202642369 83052.20162328449 74319.11342839837 74024.48715204897 0.9063347104997259 0.4658634849499148 0.6447805551386162 1.0182867078679971 0.9208622998488166 1.0100573592436684 0.9429821767362497 1.121955785423981 1.0039801191157762 1.0 16.175714969872796 -5.760516257485954 24.963332401928316 1.002092983753473 0.6516798934576202 0.6471006332991023 0.11145296969648036 13.355434813374146 361138.5277811754 0.02973976898948734 0.047937283428620976 1.7357362856782315e-06 5.760516257485954 -0.3504130902958529 EATGLS(ph)PQAAQEKDGIVIVK ddPTM_PC-9_Lapatinib_30min_R1 2 EATGLSPQAAQEKDGIVIVK 20 1 P17029;C9JRM9 P17029 ZKSCAN1 Zinc finger protein with KRAB and SCAN domains 1 1 EAT(0.068)GLS(0.932)PQAAQEKDGIVIVK;EAT(0.064)GLS(0.936)PQAAQEKDGIVIVK 83.89399999999999 0.00038236 36282000.0 165890.0 80106.0 113386.0 78856.0 73379.0 87620.0 65250.0 56427.0 97246.0 58184.0 True False 163524.37817950008 79920.51947869807 104063.84076261715 84655.33329590475 69062.9914886647 83872.69685219605 68628.32572929809 59048.80441689114 86293.13143422206 68241.02687469331 2.3962766339927675 1.1711505986779929 1.5249454108259979 1.2405342822779029 1.0120450211788388 1.229065573796335 1.0056754546691675 0.8652977119661275 1.26453448000829 1.0 16.05835173569981 -2.4220015068625393 1.0492009162059355 1.1004682242428023 199.99999999980997 0.8004088576641601 0.18522474342482584 111.3932898930382 1.0199423882484229 0.05696317043898461 52272.70524139795 0.00378441271644999 2.4220015068625393 198.89953177556717 up EATNTTSEPSAPSQDLLDLS(ph)PSPR ddPTM_PC-9_AZD4547_30min_R2 3 EATNTTSEPSAPSQDLLDLSPSPR 24 0 I3NI44;J3KQU4;I3L4I4;O75674-2;O75674-3;O75674 I3NI44 TOM1L1 TOM1-like protein 1 1 EATNTTSEPSAPS(0.002)QDLLDLS(0.652)PS(0.346)PR;EATNTTSEPSAPSQDLLDLS(0.894)PS(0.106)PR;EATNTTSEPSAPSQDLLDLS(0.909)PS(0.091)PR 129.57 5.735600000000001e-09 1562400.0 12634.400000000001 12149.8 17656.6 20844.7 18725.2 14939.0 11195.2 16577.3 10016.3 15229.400000000001 True False 16651.876388154516 16076.985247711436 17422.461947382493 16039.27646240466 16125.529200479645 14004.861968398398 12191.551112023873 14015.659193457503 10545.741169318266 14696.223341468592 1.1330718104404158 1.0939535194968577 1.185506067958373 1.0913876367914437 1.0972566778417114 0.9529565278775147 0.8295703480242274 0.9536912217378508 0.7175817163557362 1.0 13.843157836205306 -6.842666973274779 2.3930530168022117 0.8704959158306753 1.1264333969234583 0.7130288494846435 0.07415487438676736 0.14834967683366626 1.7356729827878643 0.027333134375647838 0.024013867729439822 1.4365906209211173e-07 6.842666973274779 0.255937481092783 EATNTTSEPSAPSQDLLDLSPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 EATNTTSEPSAPSQDLLDLSPSPR 24 0 I3NI44;J3KQU4;I3L4I4;O75674-2;O75674-3;O75674 I3NI44 TOM1L1 TOM1-like protein 1 1 EATNTTSEPSAPSQDLLDLS(0.17)PS(0.83)PR;EATNTTSEPSAPSQDLLDLS(0.171)PS(0.829)PR 209.0 7.6586e-31 12989300.0 16113.4 23756.0 42260.0 63392.0 56007.0 49029.0 50293.0 75763.0 57457.0 57431.0 True False 21237.12602045912 31434.662426100236 41699.604787806515 48777.953796636844 48231.3948011911 45963.208879349695 54768.979569549185 64055.56921054212 60494.05971920967 55420.35817063589 0.3832008078163499 0.5672042452218522 0.7524239496867917 0.8801450478983285 0.8702829861310096 0.8293560416522714 0.9882465826171468 1.155812977846858 1.091549418229167 1.0 15.75812841424699 -4.900430138748347 0.4577316465877588 1.0719738580069063 5.225366750286347e-16 0.8981926214167557 0.07153129402670923 1.498248268781635 0.2644732442632405 0.05865925491758588 0.8653089840331442 1.2576791502216544e-05 4.900430138748347 -1.0719738580069058 down EATNTTSEPSAPSQDLLDLSPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EATNTTSEPSAPSQDLLDLSPSPR 24 0 I3NI44;J3KQU4;I3L4I4;O75674-2;O75674-3;O75674 I3NI44 TOM1L1 TOM1-like protein 1 1 EATNTTSEPSAPSQDLLDLS(0.085)PS(0.915)PR;EATNTTSEPSAPSQDLLDLS(0.039)PS(0.961)PR 201.92 7.3187e-26 10472500.0 13733.8 14388.8 22867.0 24296.0 29324.0 25921.0 26359.0 27494.0 27909.0 23627.0 True False 16058.661085085536 15817.22497173362 23412.23600358043 22934.77388869477 23578.172704095326 24561.657128687417 23862.084697366045 26772.31163230099 28317.11632635937 27910.388068770902 0.5753650234284512 0.5667146201177907 0.8388359182213062 0.8217289502454688 0.8447812565700971 0.8800184744177598 0.8549535262128968 0.9592239121267069 1.0145726478824406 1.0 14.768514563466116 -4.210118731716734 0.35916637345740304 0.9873302177334384 7.161577084324217e-13 0.8765474893614029 0.051758012075259666 3.3103398389357186 0.24868513243896667 0.04901977115119693 1.531628712519591 6.164264540679679e-05 4.210118731716734 -0.9873302177327222 EATNTTSEPSAPSQDLLDLSPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 EATNTTSEPSAPSQDLLDLSPSPR 24 0 I3NI44;J3KQU4;I3L4I4;O75674-2;O75674-3;O75674 I3NI44 TOM1L1 TOM1-like protein 1 1 EATNTTSEPSAPSQDLLDLS(0.107)PS(0.893)PR;EATNTTSEPSAPSQDLLDLS(0.146)PS(0.854)PR 170.34 1.4438999999999998e-10 11125800.0 29068.0 24800.0 30904.0 26862.0 28759.0 25231.0 19893.4 22917.0 27525.0 21986.7 True False 28653.484989581637 24742.577123707462 28363.1924128898 28837.52108900512 27067.452162369445 24151.92894633369 20923.382912846224 23981.807482621687 24424.844648900314 25787.071799563804 1.1111569864270638 0.9594954136718226 1.099899695217414 1.1182937447551884 1.0496520261299036 0.9365905960188247 0.811390415921522 0.92999343504474 0.9471740273090435 1.0 14.654360339567178 -6.772982945829743 4.210025939587589 0.9112587590090475 1.0678819517296416 0.5794938184739085 0.06068908747329576 0.14640298078416547 5.961483461931551 0.021709553549445777 0.020107430474553014 1.6866192553971473e-07 6.772982945829743 0.1566231927205941 EATSDPS(ph)RTPEEEPLNLEGLVAHR ddPTM_PC-9_AZD4547_30min_R2 1 EATSDPSRTPEEEPLNLEGLVAHR 24 1 A0A087WWW7;E9PGF5;E9PF55;A0A494C067;A0A2R8Y4T1;Q9HBL0 A0A087WWW7 TNS1 Tensin-1 1 EAT(0.032)S(0.099)DPS(0.434)RT(0.434)PEEEPLNLEGLVAHR 106.0 5.962600000000001e-07 3721700.0 5179.6 5925.3 6493.1 11460.0 12371.0 10376.0 6612.0 10990.0 8284.1 9535.5 True False 6826.6050576272 7840.537349443158 6406.997251483828 8818.07405523502 10653.500189003784 9727.187079731026 7200.45519085875 9291.748025076331 8721.980613674665 9201.665047380313 0.7418880194482536 0.8520781085891989 0.6962867283794341 0.9583128716194141 1.157779612075404 1.0571116237816467 0.7825165504050485 1.0097898562088679 0.9478698223380547 1.0 13.167679226076247 -5.852705770073044 6.370498396289246 0.9915755056691676 0.7732491066303674 0.5365983373408603 0.09562606071164567 0.17519984077981376 10.05676675081065 0.028552644798524027 0.04286272502918292 1.4037644180511198e-06 5.852705770073044 -0.21832639903880025 EATSDPS(ph)RTPEEEPLNLEGLVAHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EATSDPSRTPEEEPLNLEGLVAHR 24 1 A0A087WWW7;E9PGF5;E9PF55;A0A494C067;A0A2R8Y4T1;Q9HBL0 A0A087WWW7 TNS1 Tensin-1 1 EAT(0.027)S(0.103)DPS(0.435)RT(0.435)PEEEPLNLEGLVAHR 94.234 2.7995e-06 2554300.0 8798.8 7698.0 9760.2 13364.0 15959.0 13580.0 14513.0 15920.0 12776.0 9830.4 True False 10288.263055778481 8462.206565690358 9992.920183764623 12615.258406672576 12831.948512640074 12867.84089377629 13138.223574979073 15502.116868634306 12962.824830182635 11612.57370259642 0.885958902760562 0.7287106874334256 0.8605258782151226 1.0863447440468745 1.1050046993261293 1.1080955198501095 1.1313791336404209 1.3349423879366409 1.116274924247354 1.0 13.503400132672592 -5.7762474655418 2.677476287825353 1.1462996791978926 0.8009975534192542 0.7225397972559737 0.08597846266093083 0.13303974312187802 1.9460851524418579 0.025557954715582098 0.045360927007506394 1.6739887479049917e-06 5.7762474655418 -0.3453021257786384 EATSDPSRT(ph)PEEEPLNLEGLVAHR ddPTM_PC-9_AZD4547_30min_R2 1 EATSDPSRTPEEEPLNLEGLVAHR 24 1 A0A087WWW7;E9PGF5;E9PF55;A0A494C067;A0A2R8Y4T1;Q9HBL0 A0A087WWW7 TNS1 Tensin-1 1 EAT(0.013)S(0.045)DPS(0.162)RT(0.78)PEEEPLNLEGLVAHR 99.881 2.362e-06 3242900.0 4031.8 3478.1 6074.4 9258.7 7835.5 6614.7 5508.3 9924.0 6829.7 5110.9 True False 5313.828533350323 4602.327807047448 5993.849487057544 7124.249760489051 6747.676075575065 6201.08176332853 5998.528029008962 8390.473830833263 7190.703998891109 4931.968946636886 1.0774253834209209 0.933162365141366 1.215305601456545 1.4445041802923522 1.3681505598643946 1.2573237646917976 1.2162542169085155 1.7012422263028915 1.4579783605074108 1.0 12.267948000730089 -5.485029224228457 3.9899507656043363 1.3690903280051616 1.0101468441825694 0.3732617161500197 0.17538515360313478 0.2131431061811307 7.252727369507122 0.04776588797323514 0.10024943174085438 3.273186684479423e-06 5.485029224228457 -0.3589434838225922 EATSDPSRT(ph)PEEEPLNLEGLVAHR ddPTM_PC-9_Lapatinib_30min_R1 1 EATSDPSRTPEEEPLNLEGLVAHR 24 1 A0A087WWW7;E9PGF5;E9PF55;A0A494C067;A0A2R8Y4T1;Q9HBL0 A0A087WWW7 TNS1 Tensin-1 1 EAT(0.014)S(0.014)DPS(0.315)RT(0.658)PEEEPLNLEGLVAHR 111.57 2.5447e-07 3393800.0 9327.4 8195.8 9791.3 8127.6 10401.0 9215.5 10894.0 9655.2 9704.2 8331.4 True False 9194.389565564325 8176.823128648451 8986.297109510997 8725.330816878793 9789.233629152772 8821.374547379743 11458.038015248623 10103.815840040535 8611.210806243727 9771.471389107313 0.9409421774302806 0.8368057176899185 0.9196462591630177 0.892939299459578 1.0018177651387548 0.9027682931368263 1.1726010913792777 1.0340117099768311 0.8812604021788387 1.0 13.254360104372347 -6.446964094388167 1.4554442837252752 1.0158847175923602 0.8907269133377431 0.27533734965564716 0.07854657694360898 0.5091431683848068 2.1922831821096223 0.031859017755003716 0.03761593124869703 3.5730237716446664e-07 6.446964094388167 -0.1251578042546171 EATTDFTVDSRPLTQVGGDHIK ddPTM_PC-9_Lapatinib_30min_R1 1 EATTDFTVDSRPLTQVGGDHIK 22 1 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 121.51 3.4551000000000003e-07 13650000.0 28861.0 26642.0 25304.0 32634.0 32005.0 23165.0 27444.0 25889.0 27873.0 22568.0 False True 28449.436847540816 26580.312085879596 23223.602796264688 35034.013223832684 30122.52882425098 22174.286950252463 28864.916035476705 27091.897452441106 24733.649224297853 26468.84873003023 1.0748271350111087 1.0042111146195378 0.8773937632548541 1.3235941457508444 1.138036985721841 0.8377503372519043 1.090524046961212 1.0235389430332116 0.9344437106641625 1.0 14.692007825323564 EATTEFSVDAR ddPTM_PC-9_Lapatinib_30min_R1 2 EATTEFSVDAR 11 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 130.41 0.00096944 19887700.0 62977.0 49958.0 62589.0 56390.0 54907.0 70776.0 55730.0 64532.0 65660.0 53273.0 False True 62078.936431432674 49842.32532041038 57443.174020526756 60537.108711525536 51677.478211315356 67749.07546691434 58615.42671101572 67530.39230564825 58264.67936954752 62481.167068189476 0.9935623699807364 0.7977175788988454 0.9193678145902036 0.9688856907147354 0.8270888755153468 1.0843119398358176 0.9381295110420259 1.0808119546158323 0.9325158620350313 1.0 15.931133780976914 -6.76041004648174 24.99986872115758 1.0078905741109767 0.9003243430866468 0.35250673025630264 0.07170510846098953 30.217154160509672 733903.4779275913 0.02286944248118732 0.021637543542623816 1.7361608290383386e-07 6.76041004648174 -0.10756623102432994 EAVAMESYAK ddPTM_PC-9_Lapatinib_30min_R1 1 EAVAMESYAK 10 0 P78371;P78371-2;F5GWF6 P78371 CCT2 T-complex protein 1 subunit beta 0 117.53 0.0021534 0.0 19911.0 18698.0 25063.0 21405.0 21021.0 22891.0 23287.0 18947.0 18962.0 19587.0 False True 19627.065488769786 18654.70592980169 23002.41688597777 22979.195104986786 19784.58610887612 21912.005291527264 24492.686915833907 19827.346789424126 16826.29988128784 22972.58685196306 0.8543689753029536 0.8120420242619565 1.0012985056583719 1.000287658201765 0.8612258704850856 0.9538327325838288 1.0661701737669544 0.863087249041343 0.7324512467715404 1.0 14.487625701583775 -5.244448918766967 24.366650140578187 0.9349880017519193 0.8332054813945208 0.16596554480112458 0.09109285035170313 1118.408067161085 1603941.0238773338 0.02408272372072577 0.06332746050554498 5.69575212990158e-06 5.244448918766967 -0.10178252035739854 EAVAPVQEES(ph)DLEK ddPTM_PC-9_AZD4547_30min_R2 2 EAVAPVQEESDLEK 14 0 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E9PGG1;E7ETL8;E7ESD3;E7EMU4;Q13409;Q13409-7;Q13409-5;E7ET01;E7ERR6;E7EUM4;E7ERH4;E7EU01 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 1 EAVAPVQEES(1)DLEK;EAVAPVQEES(1)DLEK 208.49 5.6948e-11 4366100.0 29781.0 21700.0 22442.0 30955.0 25638.0 24301.0 21795.4 26432.0 26926.0 28319.0 True False 39250.73851671858 28714.100633371578 22144.4044166577 23818.802999982538 22078.60624409337 22781.454628425563 23735.148376715475 22347.54174693519 28349.253389481528 27327.560429632755 1.4363059819330553 1.0507377966397367 0.8103322824471856 0.8716037079604998 0.8079245237036359 0.8336439210183723 0.8685425264297711 0.8177657059611709 1.0373869069827724 1.0 14.738069053711193 -4.817097136184522 2.556189733197587 0.869859680918348 1.5318722871468082 0.8297519659952204 0.07609957189440306 0.16169015796370886 1.456540318801169 0.01893328243258171 0.22801904995877043 1.5237119156765977e-05 4.817097136184522 0.6620126062284603 EAVAPVQEES(ph)DLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EAVAPVQEESDLEK 14 0 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E9PGG1;E7ETL8;E7ESD3;E7EMU4;Q13409;Q13409-7;Q13409-5;E7ET01;E7ERR6;E7EUM4;E7ERH4;E7EU01 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 1 EAVAPVQEES(1)DLEK;EAVAPVQEES(1)DLEK 205.33 1.9642999999999996e-60 0.0 19571.6 20726.8 18060.7 22403.0 21887.4 19593.3 24391.0 18449.3 15308.699999999999 19395.0 True False 22884.6853232798 22784.419725350846 18491.33558358617 21147.832541505963 17598.721090015555 18565.792855966632 22080.507904452188 17965.025423649186 15532.560776284978 22911.159969264478 0.9988444650545762 0.9944681873775202 0.8070885807786449 0.9230363093739455 0.7681287684091244 0.810338406299498 0.963744652565535 0.7841167993130608 0.6779473757383757 1.0 14.48376288225757 -5.2537499121639835 23.54965281938789 0.8375916995243067 0.9966563876873611 0.3116183754331371 0.09189425483378472 300.38112713679635 919928.4880432802 0.023077233340918886 0.05841291427996571 5.575066959221293e-06 5.2537499121639835 0.1590646881630544 EAVAPVQEES(ph)DLEK ddPTM_PC-9_Lapatinib_30min_R1 2 EAVAPVQEESDLEK 14 0 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E9PGG1;E7ETL8;E7ESD3;E7EMU4;Q13409;Q13409-7;Q13409-5;E7ET01;E7ERR6;E7EUM4;E7ERH4;E7EU01 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 1 EAVAPVQEES(1)DLEK;EAVAPVQEES(1)DLEK 181.81 2.6345e-05 4431900.0 48822.0 43746.0 38914.0 32286.0 41419.0 34773.0 37000.0 38311.0 36549.0 35679.0 True False 48125.7893271417 43644.708824746216 35714.64113238396 34660.420142938696 38982.81585288708 33285.839849822114 38915.67895760957 40091.06892118159 32432.466741967582 41846.06761072089 1.1500671885071454 1.0429823234708084 0.8534766388236186 0.8282838059091305 0.9315765633112858 0.7954353120935631 0.9299721856693516 0.9580606066532839 0.7750421627110892 1.0 15.352804434700975 -5.065684048563168 3.124769164237955 0.8808453521852052 1.1410867454112033 0.6163961349276169 0.06926922586700655 0.1570522551083023 2.874802646522229 0.017333175826751805 0.07036000950934589 8.596386855736935e-06 5.065684048563168 0.26024139322599804 EAVIT(ph)PVASATQSVSR ddPTM_PC-9_AZD4547_30min_R2 2 EAVITPVASATQSVSR 16 0 P28749;P28749-2;H0YE05 P28749 RBL1 Retinoblastoma-like protein 1 1 EAVIT(0.999)PVAS(0.001)ATQSVSR;EAVIT(1)PVASATQSVSR 202.79 5.457899999999999e-13 59071000.0 108446.0 117328.0 234130.0 300820.0 278630.0 224180.0 246740.0 265140.0 227390.0 272170.0 True False 142929.57218307172 155251.98152590898 231025.28322217544 231470.59662266992 239947.03400388957 210161.98916095818 268699.3820012838 224168.70531107724 239409.3711741146 262641.4111421007 0.544200442578876 0.5911176796179745 0.8796224564038018 0.8813179750143592 0.9135917788458254 0.8001860340571015 1.0230655585988513 0.8535162232653097 0.9115446423054112 1.0 18.002734880915725 -5.248572626029903 3.515286364227266 0.9049709344042254 0.5510764038785645 0.8331539042147444 0.06115187145393337 0.08155359127519773 2.168254192199843 0.015383065548928598 0.04323221362618826 5.641925848761176e-06 5.248572626029903 -0.3538945305256609 EAVIT(ph)PVASATQSVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EAVITPVASATQSVSR 16 0 P28749;P28749-2;H0YE05 P28749 RBL1 Retinoblastoma-like protein 1 1 EAVIT(1)PVASATQSVSR;EAVIT(0.994)PVAS(0.005)ATQSVSR 161.48 1.5582e-05 44824000.0 111029.0 131981.0 191975.0 216950.0 210433.0 189085.0 201197.0 204680.0 183311.0 138910.0 True False 129824.01677729115 145083.20144795763 196552.4120692419 204794.99486139035 169200.16425593046 179169.0497348815 182138.16361986246 199307.3668763863 185991.5765846598 164093.2833890452 0.7911598457658637 0.8841507613933414 1.1978090023541066 1.248040082029722 1.0311218153565584 1.0918731469958676 1.109967208030295 1.214597957698566 1.1334502713538641 1.0 17.324156662589914 -5.140643355427664 4.318230341849474 1.134397894345481 0.8122018099289803 0.7109713983213808 0.07483200691520937 0.11450788646208576 3.4293105884904604 0.019682320448051478 0.05879489962723147 7.23363589176147e-06 5.140643355427664 -0.3221960844165008 EAVIT(ph)PVASATQSVSR ddPTM_PC-9_Lapatinib_30min_R1 2 EAVITPVASATQSVSR 16 0 P28749;P28749-2;H0YE05 P28749 RBL1 Retinoblastoma-like protein 1 1 EAVIT(0.997)PVAS(0.002)AT(0.001)QSVSR;EAVIT(1)PVASATQSVSR 174.68 3.0557e-05 58195000.0 226806.0 209205.0 220277.0 228906.0 204900.0 203879.0 154982.0 151981.0 209853.0 152678.0 True False 223571.70484887337 208720.59867601673 202166.67535380958 245740.51084803135 192848.18484889946 195159.5704351617 163006.20962725018 159042.59209391812 186217.14528994306 179068.18886935263 1.2485283190750889 1.165592839207741 1.1289926850229635 1.3723292361398851 1.0769539026811772 1.089861754158631 0.9103024420835507 0.8881677594335581 1.0399230955857062 1.0 17.450149542432605 -6.806007670351208 1.9385748188668908 0.9545148258841855 1.2144290161906781 0.6702463652153915 0.0803607149646892 0.19367273397672335 1.498914709181677 0.032827879729731134 0.029170385718222207 1.5631200351395282e-07 6.806007670351208 0.25991419030649265 EAVREGS(ph)PANWK ddPTM_PC-9_AZD4547_30min_R2 1 EAVREGSPANWK 12 1 O96019-2;O96019 O96019-2 ACTL6A Actin-like protein 6A 1 EAVREGS(1)PANWK 89.507 0.035976 7976100.0 25954.0 15733.0 27252.0 63287.0 49512.0 28953.0 19392.0 29510.0 20566.0 36777.0 True False 34206.83212326362 20818.384574416374 26890.620673859532 48697.15992440301 42638.1134393303 27142.56433302356 21117.850432718227 24949.907572338736 21653.076773678862 35489.44842404758 0.9638592213252077 0.586607724235857 0.7577074839979339 1.3721588271122835 1.2014307162474467 0.7648065985334338 0.5950458902711154 0.7030232556511847 0.6101271711793295 1.0 15.11510253179911 -6.979945171019652 24.275587646733154 0.6991045763457973 0.9664002727080605 0.21742280647387147 0.22737181698300724 277.90369128756447 336389.7921433886 0.0879214455983556 0.07752876506567827 1.0472607546924233e-07 6.979945171019652 0.26729569636226325 EAVREGS(ph)PANWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAVREGSPANWK 12 1 O96019-2;O96019 O96019-2 ACTL6A Actin-like protein 6A 1 EAVREGS(1)PANWK 98.25299999999999 0.017936 8662400.0 16353.0 8250.7 10280.0 14861.0 16049.0 19394.0 18270.0 19838.0 21145.0 12607.0 True False 19121.239913527483 9069.774969023309 10525.114187117104 14028.386350012062 12904.313658710471 18376.944498814246 16539.333336654556 19317.273520098457 21454.205622590143 14892.549303042915 1.2839467256032882 0.6090142650842277 0.7067369040011547 0.9419734703947373 0.8664946072109898 1.2339690220168942 1.1105777123917369 1.297109925709728 1.4405999393405748 1.0 13.862303114802678 -6.758708964156694 10.570135493191355 1.228523826111151 0.8599844081282311 0.41619139579070674 0.19718575092376558 0.1017546122425552 225.22205572148923 0.06637149323019591 0.06284846201652176 1.7429745099757178e-07 6.758708964156694 -0.36853941798292 EAVREGS(ph)PANWK ddPTM_PC-9_Lapatinib_30min_R1 2 EAVREGSPANWK 12 1 O96019-2;O96019 O96019-2 ACTL6A Actin-like protein 6A 1 EAVREGS(1)PANWK;EAVREGS(1)PANWK 104.7 0.009072 16200000.0 84216.0 33120.0 46536.0 40136.0 28507.0 34807.0 23033.0 23959.0 41639.0 19379.4 True False 83015.06439667699 33043.31267488674 42709.9897141548 43087.73532977104 26830.274306918396 33318.38574907996 24225.53603866546 25072.222606629686 36949.1773418914 22729.103468572677 3.652368625602024 1.453788651214309 1.8790881819518095 1.8957076502972525 1.1804369822160548 1.4658908916116724 1.0658377296826462 1.1030889379907491 1.6256328540622242 1.0 14.472253158867865 -2.9581200368779363 1.241776764485902 1.3620909156594458 199.99999998727282 0.8099655576517274 0.32257288701942405 56.77792208719719 1.2933318770788382 0.09655142281765156 31014.941103773268 0.0011012348915172075 2.9581200368779363 198.63790907161336 up EAVSTPS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAVSTPSR 8 0 Q8IVM0-2;Q8IVM0 Q8IVM0-2 CCDC50 Coiled-coil domain-containing protein 50 1 EAVS(0.085)T(0.289)PS(0.626)R 86.189 0.012662 13359000.0 75240.0 79455.0 85534.0 69186.0 83005.0 73715.0 79835.0 85156.0 68752.0 61386.0 True False 87976.64594226204 87342.76730019823 87573.45494950145 65309.7327240384 66740.76610637813 69849.25563215897 72272.45084465345 82920.74523023998 69757.36793399477 72514.79586869132 1.2132233827365217 1.2044820129999012 1.2076632623785926 0.9006400961577588 0.9203744602305891 0.9632414294958636 0.9966579920534189 1.1435010501910754 0.9619742715722505 1.0 16.14598777120853 -5.747077607472439 24.985913169102727 0.9867892912105845 1.2080589136043138 0.7366728291069133 0.0615410679053852 132.213268427082 230016.328633291 0.018462050085358984 0.031789721155547616 1.7902859052800637e-06 5.747077607472439 0.22126962239372938 EAVTHIGR ddPTM_PC-9_AZD4547_30min_R2 1 EAVTHIGR 8 0 D6RBW1;P06730;P06730-3;P06730-2 D6RBW1 EIF4E Eukaryotic translation initiation factor 4E 0 101.72 0.004437600000000001 0.0 20874.0 20511.0 34446.0 33803.0 32009.0 34244.0 26599.0 30813.0 25467.0 23092.0 False True 27511.497793827744 27140.779635533832 33989.223533383425 26010.240601143934 27565.10286555832 32102.71726660652 28966.259470909252 26051.5588623 26813.133628089043 22283.55610865776 1.2346098468160918 1.2179734465716139 1.525305178744684 1.1672392177583477 1.2370154355591627 1.4406460580200549 1.299893936572138 1.169093421860897 1.203269958230384 1.0 14.44369186226955 -8.541800455428355 1.034925554422711 1.00518984514259 1.3042781863755586 0.4222425650779047 0.10590724790642195 0.5681745185766657 1.334065122853885 0.10175445204886549 0.0333923725367807 2.8720999179326565e-09 8.541800455428355 0.29908834123296857 EAVVDLHADDS(ph)RISEDETER ddPTM_PC-9_AZD4547_30min_R2 1 EAVVDLHADDSRISEDETER 20 1 Q9UKV3-5 Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 EAVVDLHADDS(0.469)RIS(0.469)EDET(0.063)ER 71.637 0.0017239999999999998 22904000.0 34239.0 38612.0 52169.0 61879.0 52113.0 48372.0 56570.0 64098.0 39568.0 57492.0 True False 45126.289784558234 51092.57390118634 51477.20497338093 47613.752571019904 44878.009485858405 45347.29119321021 61604.6204093889 54193.126925508914 41659.483700326986 55479.22257920286 0.8133908098682413 0.9209316844381861 0.9278645694771841 0.8582267443103747 0.8089156156034806 0.8173743085255354 1.110408862010302 0.9768184269010276 0.7509024417357933 1.0 15.75965995111531 EAVVDLHADDS(ph)RISEDETER ddPTM_PC-9_Lapatinib_30min_R1 1 EAVVDLHADDSRISEDETER 20 1 Q9UKV3-5 Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 EAVVDLHADDS(0.894)RIS(0.057)EDET(0.048)ER 99.37100000000001 0.00017055 4237900.0 4650.7 6919.3 6082.6 6821.5 7531.4 6730.8 7139.9 6919.6 7806.0 8302.5 True False 4584.3801651660715 6903.278785970528 5582.512107514999 7323.17586585692 7088.417859302103 6442.939374261145 7509.569086200995 7241.1098772417445 6926.806079175877 9737.57606261415 0.4707927451028659 0.7089319499618136 0.573295866611831 0.7520532644641484 0.727944799991544 0.6616574117451847 0.7711949090731905 0.743625500913191 0.7113480844345063 1.0 13.249346977128065 -14.522878745208887 0.060687877784206944 2.109692464381594 0.21927959399007646 0.7075115969782799 0.07036312671542388 219.7167064690082 0.9694725513336255 36.33834936204548 5.908421783433606 3.000000000493563e-15 14.522878745208887 -1.8904128703915175 EAVVDLHADDSRIS(ph)EDETER ddPTM_PC-9_AZD4547_30min_R2 1 EAVVDLHADDSRISEDETER 20 1 Q9UKV3-5 Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 EAVVDLHADDS(0.278)RIS(0.615)EDET(0.107)ER 58.635 0.0079477 16260000.0 32590.0 32744.0 34209.0 36414.0 39245.0 44765.0 37438.0 33652.0 33707.0 24436.0 True False 42952.94208588895 43327.857656180626 33755.366308236466 28019.31489069181 33796.509168010125 41965.83747341549 40769.909472983956 28451.856646029915 35488.68320579565 23580.503077739544 1.8215447713003785 1.8374441594116357 1.431494747883568 1.1882407596783884 1.433239530835739 1.7796837215501167 1.7289669070492202 1.2065839542197478 1.505001105735427 1.0 14.525306877342011 -12.518401749803576 0.12551857857438267 1.8349320688099817e-19 1.8220320563704375 0.40530531123759983 0.21673845247851198 97.24740599924651 1.2935627954349282 29.32611685154886 2.3434420557301054 3.03108594109707e-13 12.518401749803576 1.8220320563704375 EAVVDLHADDSRIS(ph)EDETER ddPTM_PC-9_Lapatinib_30min_R1 3 EAVVDLHADDSRISEDETER 20 1 Q9UKV3-5 Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 EAVVDLHADDS(0.229)RIS(0.433)EDET(0.337)ER;EAVVDLHADDS(0.169)RIS(0.733)EDET(0.098)ER;EAVVDLHADDS(0.075)RIS(0.825)EDET(0.101)ER 85.046 0.00036858 44650300.0 56776.8 60144.9 69352.9 63912.0 73895.0 83387.2 74187.7 78659.0 73870.2 65782.3 True False 55967.15242041007 60005.63817934165 63650.97227193576 68612.30168418195 69548.64138315963 79820.92384105729 78028.7761027961 82313.78429879734 65550.16018830877 77152.6829055948 0.7254077280616713 0.7777518022641605 0.8250001150293121 0.8893054538121118 0.9014416448519412 1.0345839034363509 1.0113553173293182 1.0668946457703583 0.8496160822886346 1.0 16.235428705461437 -5.8380143985171244 0.9595581497834786 0.9966837209642255 0.7302058504267145 0.727384481005682 0.05753151037394494 0.33457638391169625 0.5935681417209305 0.023641644095052754 0.06523354640892895 1.4520634753518325e-06 5.8380143985171244 -0.26647787053751104 EAVVDLHADDSRISEDET(ph)ER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAVVDLHADDSRISEDETER 20 1 Q9UKV3-5 Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 EAVVDLHADDS(0.079)RIS(0.139)EDET(0.782)ER 93.738 0.00043708 16682000.0 26437.0 34556.0 27814.0 27444.0 33658.0 27434.0 29219.0 17470.0 24556.0 22304.0 True False 30912.261945448896 37986.491307352 28477.191245182385 25906.401654648493 27062.956515974663 25995.312745203144 26451.164792759155 17011.431010995053 24915.08504461215 26347.538641633142 1.1732504643375983 1.4417472472106951 1.0808292809630446 0.9832569944014586 1.0271531198444113 0.9866315445544721 1.0039330486439544 0.6456554155732175 0.9456323561565065 1.0 14.68538057270722 -5.680486842481175 0.7984664050035909 0.889396310792713 1.357456952208255 0.549822988185402 0.12608154577816424 0.6900782594096363 0.7413485496432686 0.05831576094057575 0.23144462870980856 2.086955349995941e-06 5.680486842481175 0.46806064141554193 EAWPHIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAWPHIK 7 0 P52209-2;P52209;K7EMN2;K7EM49;K7EPF6 P52209-2 PGD 6-phosphogluconate dehydrogenase, decarboxylating 0 68.422 0.041263 3253500.0 16893.0 15793.0 16580.0 15838.0 21644.0 17651.0 18017.0 17576.0 17676.0 13889.0 False True 19752.651248041315 17360.82466769911 16975.330080000145 14950.648207488803 17403.013572754044 16725.350487190375 16310.299328215946 17114.648623311336 17934.478060293393 16406.965754736488 1.2039186003870928 1.058137435478419 1.0346416475636013 0.9112378504948567 1.0607088375088496 1.0194054609007746 0.994108208186353 1.0431330740341522 1.0931014502249408 1.0 14.00202083623482 -4.726302187265656 2.357271819495243 1.018201044150816 1.2655613794427774 0.596347559793113 0.04544387162667742 0.4981548819099132 2.9551609131384917 0.012112187380929553 0.270588198275935 1.8780096206451185e-05 4.726302187265656 0.24736033529196133 EAWPHIK ddPTM_PC-9_Lapatinib_30min_R1 2 EAWPHIK 7 0 P52209-2;P52209;K7EMN2;K7EM49;K7EPF6 P52209-2 PGD 6-phosphogluconate dehydrogenase, decarboxylating 0 ; 94.887 0.011165999999999999 13772600.0 192609.0 191068.0 201296.0 198057.0 194151.0 213214.0 191154.0 166859.0 184347.0 187896.0 False True 189862.3603398354 190625.5937851831 184746.21990503086 212622.7724787839 182731.41989555236 204095.33424610985 201051.01879629464 174611.8782887275 163583.89960003 220373.57324431813 0.8615477688395226 0.8650111307758539 0.838332006806511 0.964828810226981 0.8291893497273667 0.9261334344288127 0.9123190945104772 0.7923449065062954 0.7423027053188088 1.0 17.74959170363055 -7.757911478736799 24.999775802851833 0.8254928539882712 0.8852145969392109 0.04135246092570777 0.07316055732118223 189.35234309905024 1341838.5978047296 0.03419025687508899 0.01872515518413527 1.7461780361744346e-08 7.757911478736799 0.05972174295093968 EAYPEEAYIADLDAK ddPTM_PC-9_Lapatinib_30min_R1 2 EAYPEEAYIADLDAK 15 0 P53396;P53396-2 P53396 ACLY ATP-citrate synthase 0 ; 175.48 0.00028055 11876100.0 59390.0 58215.0 54364.0 54175.0 58869.0 44626.0 60008.0 54106.0 48778.0 47733.0 False True 58543.087709207844 58080.206744218944 49894.40177110862 58159.210222502195 55406.44116090709 42717.45000828694 63114.920618600976 56619.96228366405 43284.10798488866 55983.58544977549 1.045718798445458 1.037450643391256 0.8912326956241547 1.038861833432918 0.989690830191893 0.7630352658746734 1.1273826088760108 1.0113672039540853 0.7731571252027095 1.0 15.772716266334601 -5.14803891026294 8.305689754279294 0.9541518950973663 1.0432933710479482 0.10302591607638123 0.10820448611766555 0.7187011675487708 47.79059219811319 0.02714046443955995 0.07250757046471039 7.111497959080655e-06 5.14803891026294 0.08914147595058186 EAYPGDVFYLHSR ddPTM_PC-9_AZD4547_30min_R2 2 EAYPGDVFYLHSR 13 0 P25705-2;P25705;P25705-3 P25705-2 ATP5A1 ATP synthase subunit alpha, mitochondrial 0 ; 151.66 0.00011329 15761300.0 63816.0 75266.0 102355.0 145685.0 117402.0 85703.0 86714.0 115330.0 87586.0 104894.0 False True 84108.16054474041 99594.26259314951 100997.70582243118 112099.57406081262 101102.7588060321 80343.97786181446 94431.37801272329 97508.39851974997 92215.61714963705 101221.6929872488 0.8309301895922229 0.9839221184108796 0.9977871624331967 1.1074659072826825 0.9988250129225592 0.7937426799602694 0.9329164058204311 0.9633152305803994 0.9110262279574175 1.0 16.62715898394827 EAYPGDVFYLHSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EAYPGDVFYLHSR 13 0 P25705-2;P25705;P25705-3 P25705-2 ATP5A1 ATP synthase subunit alpha, mitochondrial 0 ; 127.78 9.4821e-05 11814600.0 71819.0 69254.0 84357.0 85914.0 112885.0 96649.0 85099.0 85089.0 91471.0 63893.0 False True 83976.53821009194 76129.07943625879 86368.39080570382 81100.51711694617 90765.99460175296 91580.55629915933 77037.80665659366 82855.50390924785 92808.59032886956 75476.29512329033 1.1126213610898161 1.0086488653411265 1.1443114777245131 1.0745164025932736 1.2025761790968534 1.213368464225261 1.0206887676554952 1.0977685612933652 1.2296389240789702 1.0 16.203735987193184 -5.282249557930834 24.219223380350005 1.127054456248472 1.0606350944974539 0.09102549710630303 0.07775253440519947 1082.4575462172227 1259780.594442849 0.02008981105382938 0.04189822034711096 5.22096091558331e-06 5.282249557930834 -0.06641936175101804 EAYPGDVFYLHSR ddPTM_PC-9_Lapatinib_30min_R1 2 EAYPGDVFYLHSR 13 0 P25705-2;P25705;P25705-3 P25705-2 ATP5A1 ATP synthase subunit alpha, mitochondrial 0 ; 142.85 5.8216000000000006e-05 15176600.0 57596.0 49063.0 49093.0 40346.0 38491.0 38245.0 33181.0 25192.0 47354.0 28729.0 False True 56774.67047818716 48949.397637921706 45056.763044460255 43313.17943031052 36227.03505621763 36609.35050344942 34898.9498241201 26362.512287917496 42020.49386027342 33694.769371013776 1.684969849564487 1.452729861390025 1.3372034854531676 1.285457067635283 1.0751530796166322 1.0864995127387025 1.0357379045942434 0.7823918305431727 1.2470924907538297 1.0 15.04023703065425 -5.0924395827602345 0.566397990269902 0.9886031996377665 1.96119971701993 0.7914515045849664 0.11160400674622917 1.2170636060320204 0.38025938544679977 0.062213589551199044 0.7431761348771011 8.082773654726467e-06 5.0924395827602345 0.9725965173821635 EAYSGCSGPVDSECPPPPS(ph)SPVHK ddPTM_PC-9_AZD4547_30min_R2 1 EAYSGCSGPVDSECPPPPSSPVHK 24 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 EAYSGCSGPVDSECPPPPS(0.5)S(0.5)PVHK 175.0 1.4383e-14 38751000.0 9736.7 9426.3 17081.0 22703.0 18243.0 17672.0 18608.0 23091.0 20735.0 17646.0 True False 12832.768064058757 12473.167133656707 16854.494779472865 17469.17410785345 15710.27434710178 16566.967046357626 20264.075951527462 19522.81652839286 21831.009768658518 17028.21891102439 0.7536177524562232 0.7324998109803101 0.9897978683232073 1.0258955560257437 0.9226023243646846 0.9729125008859183 1.1900290956682569 1.1464978592537016 1.28204892612255 1.0 14.055639921869986 -5.136696888113872 0.4464456795647668 1.16067436636777 0.5025016590097879 0.6618922249679909 0.0967512069514603 2.3250141529083463 0.4564644571225727 0.07732298815660994 0.7856078855643002 7.299668062020171e-06 5.136696888113872 -0.6581727073579822 EAYSGCSGPVDSECPPPPS(ph)SPVHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EAYSGCSGPVDSECPPPPSSPVHK 24 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 EAYSGCSGPVDSECPPPPS(0.971)S(0.029)PVHK 180.21 5.189100000000001e-15 55059000.0 38422.0 46803.0 57320.0 55714.0 68790.0 55824.0 71681.0 64402.0 56009.0 51431.0 True False 44926.085730908875 51449.292529748716 58686.726187310545 52592.52520722511 55311.09331314687 52896.49116746447 64890.856754501096 62711.515739559414 56828.025666382244 60755.03317242803 0.7394627800367545 0.846831774146698 0.9659566149976834 0.8656488600370439 0.9103952450518661 0.8706520004250455 1.068073760577749 1.0322028063350523 0.9353632563264248 1.0 15.890716311430266 -2.8640871490316853 0.31779801102082367 1.0062874545002762 1.2606804568482227e-15 0.6026442067506277 0.05865159240457393 18.320115123151997 0.5635101356239877 0.06133657411450562 9.065202567265718 0.0013674543936399173 2.8640871490316853 -1.006287454500275 EAYSGCSGPVDSECPPPPS(ph)SPVHK ddPTM_PC-9_Lapatinib_30min_R1 2 EAYSGCSGPVDSECPPPPSSPVHK 24 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 EAYSGCSGPVDSECPPPPS(0.863)S(0.137)PVHK;EAYSGCSGPVDSECPPPPS(0.855)S(0.145)PVHK 209.29 7.094199999999999e-31 129690000.0 41433.0 97024.0 121859.0 119505.0 128348.0 155019.0 155788.0 141441.0 169718.0 142318.0 True False 40842.15782211835 96799.34688913696 111840.22340934281 128293.79635699328 120798.82298187679 148389.19873693876 163853.94036346185 148012.86521575652 150602.57163022945 166917.47667318478 0.24468473065936078 0.5799233778177988 0.6700330345175287 0.7686061334858629 0.723703864864877 0.8889973757959249 0.9816464017382603 0.8867427675387015 0.9022576582864417 1.0 17.348775490789393 -4.91450776545937 0.5677276779739514 0.9361770402183455 1.0639323791095497e-21 0.9072073724377624 0.06582264082478144 1.032490212054618 0.28165822181687117 0.0377955540143169 0.6259964638632569 1.2175652218161843e-05 4.91450776545937 -0.9361770402183455 down EAYSGCSGPVDSECPPPPS(ph)SPVHKAELEK ddPTM_PC-9_AZD4547_30min_R2 3 EAYSGCSGPVDSECPPPPSSPVHKAELEK 29 1 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 EAYSGCSGPVDSECPPPPS(0.5)S(0.5)PVHKAELEK;EAYSGCSGPVDSECPPPPS(0.5)S(0.5)PVHKAELEK;EAYSGCSGPVDSECPPPPS(0.5)S(0.5)PVHKAELEK 126.1 1.74e-12 54006700.0 124588.0 67026.9 164025.0 339192.0 265908.0 168153.0 121008.0 160522.0 119380.0 193894.0 True False 164204.392408614 88692.03464253157 161849.92132796906 260996.5248641601 228991.2641061856 157638.36632787288 131777.47757644195 135717.01332859872 125690.18308089959 187105.83007674 0.8776016885271123 0.4740206898211307 0.865018055619045 1.3949139091877276 1.2238595879789882 0.8425091097547239 0.7042938080678428 0.7253489283200606 0.6717598432360378 1.0 17.513494987006737 -10.813148384379966 4.304416468964002 1.0001148542635847 0.8696453220661932 0.024618051142040853 0.25417238421614413 0.00031558165322568416 5.20342030502478e-05 0.27722330016321445 0.06717742416981073 1.5376291923736928e-11 10.813148384379966 -0.13046953219739155 EAYSGCSGPVDSECPPPPS(ph)SPVHKAELEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EAYSGCSGPVDSECPPPPSSPVHKAELEK 29 1 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 EAYSGCSGPVDSECPPPPS(0.5)S(0.5)PVHKAELEK;EAYSGCSGPVDSECPPPPS(0.5)S(0.5)PVHKAELEK 98.37700000000001 4.4056000000000005e-11 19776800.0 49812.0 17395.9 50324.0 95902.0 107275.0 131801.0 97931.0 142074.0 128852.0 93556.0 True False 58244.1877681545 19122.84998650206 51523.91501483279 90528.9218584789 86255.23383003072 124889.12353760001 88654.26672095885 138344.70803984615 130736.21673596528 110516.96221111176 0.5270158227557437 0.17303090497523088 0.4662082089843435 0.8191405196746967 0.7804705459173245 1.1300448459579828 0.8021779186403049 1.2517961521198644 1.1829515951246496 1.0 16.753908286766844 -6.028922908847403 0.9845598410584551 1.0902346469065007 0.30110685347999466 0.7762028442146304 0.15530291535186208 0.25854302258972295 0.5116343070157618 0.0661549217636645 0.13775215017397943 9.35571731754009e-07 6.028922908847403 -0.7891277934265061 EAYSGCSGPVDSECPPPPS(ph)SPVHKAELEK ddPTM_PC-9_Lapatinib_30min_R1 2 EAYSGCSGPVDSECPPPPSSPVHKAELEK 29 1 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 EAYSGCSGPVDSECPPPPS(0.5)S(0.5)PVHKAELEK;EAYSGCSGPVDSECPPPPS(0.5)S(0.5)PVHKAELEK 93.949 6.830199999999999e-11 24552000.0 159680.0 83685.0 132889.0 114468.0 111099.0 126788.0 83062.0 76140.0 160524.0 97835.0 True False 157402.93391827444 83491.23252409123 121963.37938637442 122886.35857405404 104564.37524903785 121365.57279726367 87362.54393451274 79677.74236273568 142444.09672734147 114745.64939305678 1.371755136258777 0.7276200271270874 1.0629019926375909 1.0709456892183473 0.9112709353437587 1.0576921516347046 0.7613582248792347 0.6943857373607487 1.2413899566632347 1.0 16.808079929007924 -6.668177374980346 1.683478080790767 0.9109297639631999 1.0309657839482194 0.046288227769890944 0.2048935736252403 1.1727894352335546 6.861624375748062 0.0822970174650363 0.08059385216842488 2.1469534342043013e-07 6.668177374980346 0.12003601998501945 EAYSGCSGPVDSECPPPPSS(ph)PVHK ddPTM_PC-9_AZD4547_30min_R2 3 EAYSGCSGPVDSECPPPPSSPVHK 24 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 EAYSGCSGPVDSECPPPPS(0.261)S(0.739)PVHK;EAYSGCSGPVDSECPPPPS(0.243)S(0.757)PVHK;EAYSGCSGPVDSECPPPPS(0.251)S(0.749)PVHK 194.43 5.853399999999999e-25 268317000.0 259889.0 255969.0 371576.0 369426.0 376727.0 429172.0 364077.0 455761.0 383334.0 360034.0 True False 342528.29597298615 338705.97350338666 366648.65945655503 284260.5432748039 324424.95883136604 402335.8069952125 396479.14768939425 385333.6097958884 403596.25264812814 347429.3192458206 0.9858934666669086 0.9748917398181304 1.0553187055498214 0.8181823684076526 0.9337869340895263 1.1580364255629887 1.1411793010159539 1.10909928566866 1.1616643452090671 1.0 18.40635998135133 -6.758071707327529 24.99994925264013 1.1225135512168352 0.9529228944469311 0.566601612266107 0.06993453142023946 63.500741792121616 471398.26336625766 0.023778398897673535 0.022856372910535893 1.7455339201391594e-07 6.758071707327529 -0.16959065676990404 EAYSGCSGPVDSECPPPPSS(ph)PVHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EAYSGCSGPVDSECPPPPSSPVHK 24 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 EAYSGCSGPVDSECPPPPS(0.211)S(0.789)PVHK;EAYSGCSGPVDSECPPPPS(0.054)S(0.946)PVHK;EAYSGCSGPVDSECPPPPS(0.264)S(0.736)PVHK 193.42 6.5398e-25 184559000.0 72653.0 82265.0 97186.0 102426.0 125663.0 97659.0 130207.0 107110.0 102589.0 86995.0 True False 84951.71793784101 90431.72552955516 99503.28281995752 96687.40328957225 101040.23722939342 92537.59012115601 117872.8503429544 104298.47599242564 104089.17004568008 102766.504847959 0.8266479244723306 0.8799727660617348 0.9682462487867096 0.9408454966199282 0.9832020401869309 0.9004645069720288 1.1469967818536297 1.0149073002602662 1.0128705865756351 1.0 16.649010591458854 -3.5717352529996 0.3776894250726131 1.0348468244571694 0.36275837621148516 0.5548968907157976 0.05603070558922145 11.16308985036494 0.6179331833306994 0.04637885282965855 4.092089934265208 0.0002680802050429495 3.5717352529996 -0.6720884482456841 EAYSGCSGPVDSECPPPPSS(ph)PVHK ddPTM_PC-9_Lapatinib_30min_R1 2 EAYSGCSGPVDSECPPPPSSPVHK 24 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 EAYSGCSGPVDSECPPPPS(0.232)S(0.768)PVHK;EAYSGCSGPVDSECPPPPS(0.227)S(0.773)PVHK 170.58 1.3255000000000002e-10 160724000.0 46056.0 100668.0 126623.0 107294.0 143236.0 156944.0 139628.0 145053.0 169002.0 133651.0 True False 45399.232994364014 100434.90943102371 116212.54571891506 115184.75868229155 134811.14009281094 150231.87097433308 146857.25463494903 151792.6919220112 149967.21509004367 156752.3972712369 0.2896238512755077 0.6407232755569021 0.7413765131631537 0.7348197583414391 0.860026018355178 0.9584023822894332 0.9368740586520933 0.9683596204232612 0.9567140133145621 1.0 17.258127981291103 -4.812667861176785 0.5909351270258112 0.9702905745051816 3.989934735745591e-16 0.9328600065761603 0.05392530837310214 0.9004809822644969 0.24483132922596412 0.028906618432735492 0.5972719455060496 1.5393314369202162e-05 4.812667861176785 -0.9702905745051812 down ECEEEAINIQSTAPEEEHES(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 ECEEEAINIQSTAPEEEHESPR 22 0 P46939;P46939-2 P46939 UTRN Utrophin 1 ECEEEAINIQSTAPEEEHES(1)PR;ECEEEAINIQST(0.001)APEEEHES(0.999)PR 127.11 4.6559e-07 23847000.0 68309.5 96375.0 78560.0 62905.0 78893.0 98902.0 89536.0 118521.0 100149.0 81391.0 True False 90030.50007413402 127526.33403415608 77518.2430698079 48403.22412256184 67940.06874230673 92717.64230527742 97504.53054578483 100206.3027916355 105442.67168176435 78541.52586349248 1.1462789789774357 1.6236803733072447 0.9869714424002523 0.6162755763962122 0.8650209936128386 1.1804919917958234 1.2414392192386308 1.275838503135234 1.3425085713896985 1.0 16.261168005747166 -6.984076246603532 24.40638724100028 1.2340806564887445 1.049356080228424 0.09155763812988527 0.251599019193548 484.53632153706695 742646.7118989675 0.09978234533692934 0.0879710211841285 1.0373462788643898e-07 6.984076246603532 -0.18472457626032046 ECEEEAINIQSTAPEEEHES(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 ECEEEAINIQSTAPEEEHESPR 22 0 P46939;P46939-2 P46939 UTRN Utrophin 1 ECEEEAINIQSTAPEEEHES(1)PR;ECEEEAINIQSTAPEEEHES(1)PR 184.95 1.391e-15 34030000.0 182281.0 255727.0 189933.0 178015.0 222017.0 197195.0 208296.0 204175.0 230662.0 185154.0 True False 179681.6395137584 255134.8798433199 174317.4419025823 191106.81694063154 208958.39656221602 188761.42953399668 219080.5476798443 213661.71587748308 204682.41658145862 217157.6221978028 0.8274249722171457 1.1748833739343707 0.8027231102383384 0.880037343412048 0.9622429756201772 0.8692369515911312 1.0088549757663583 0.9839015260669257 0.9425523014569535 1.0 17.7283830664825 -7.282452730725187 24.679437338488423 0.9824856581737146 0.925887854782275 0.09165710126974025 0.09802822350751002 2105.2306894683325 2472507.017925682 0.04024542564964606 0.027166191869547895 5.2185190030604017e-08 7.282452730725187 -0.056597803391439605 ECELS(ph)PGVNR ddPTM_PC-9_AZD4547_30min_R2 2 ECELSPGVNR 10 0 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;H7C3A1 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 1 ECELS(1)PGVNR;ECELS(1)PGVNR 93.561 0.0067150000000000005 10158900.0 33170.0 37619.0 49612.0 61554.0 53842.0 48453.0 45004.0 64574.0 42030.0 48403.0 True False 43717.370021139526 49778.606070359725 48954.112464095066 47363.67629981992 46366.9676805708 45423.22625040551 49009.26881569981 54595.57206290072 44251.619994054396 46708.4257027266 0.9359632520988077 1.0657307610231423 1.048078836475051 1.0140285309820465 0.9926895840093393 0.972484633489883 1.0492597016139402 1.1688591777931343 0.9474012306835512 1.0 15.511395199786154 -7.492545717496915 23.996290632193034 1.056689979993349 1.0095499395491707 0.05256885308422754 0.06282805181253799 928.9568222329175 734894.6253761315 0.02560679049726112 0.017230576949775936 3.217023863828944e-08 7.492545717496915 -0.04714004044417819 ECELS(ph)PGVNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ECELSPGVNR 10 0 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;H7C3A1 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 1 ECELS(1)PGVNR 81.771 0.015829 4350500.0 13730.0 17351.0 18179.0 19901.0 23956.0 17302.0 17308.0 15605.0 17970.0 14780.0 True False 16054.217820138962 19073.492611235823 18612.456304241423 18786.01148991252 19261.993769584904 16394.65266156977 15668.460940931427 15195.385284864216 18232.777254100016 17459.49700158437 0.919512046577408 1.0924422742250244 1.0660362267339334 1.075976672650293 1.1032387569834896 0.939010594639813 0.897417659827748 0.8703220535783651 1.0442899501884548 1.0 14.09172437587231 -6.776660585347079 24.592070972756694 0.9388037317463525 1.05589294340246 0.3613425750351449 0.06630112575805099 192.16523561006466 310468.5937294228 0.023021403448105004 0.020383188717091223 1.6723971341068374e-07 6.776660585347079 0.11708921165610753 ECHLNADTVSSK ddPTM_PC-9_Lapatinib_30min_R1 1 ECHLNADTVSSK 12 0 A0A087X253;P63010-3;P63010;P63010-2 A0A087X253 AP2B1 AP-2 complex subunit beta 0 97.95700000000001 0.0031965 2152300.0 60096.0 50390.0 53318.0 44686.0 57272.0 56205.0 47983.0 46900.0 60185.0 43300.0 False True 59239.02001974332 50273.325050952364 48934.399853431896 47972.3575081261 53903.37356108429 53801.24317025423 50467.32495737784 49079.14521686768 53406.331523853456 50784.34730637669 1.1664818622628046 0.9899374062574561 0.963572487369302 0.9446288089263776 1.0614170786894404 1.059406018269309 0.9937574791089411 0.9664226837607718 1.0516297709146207 1.0 15.632096279239443 ECINAAPDS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 3 ECINAAPDSPSK 12 0 J3KNN7;Q7Z569 J3KNN7 BRAP BRCA1-associated protein 1 ECINAAPDS(0.569)PS(0.431)K;ECINAAPDS(0.986)PS(0.014)K;ECINAAPDS(0.97)PS(0.03)K 155.06 0.00029953 66096400.0 71452.0 76863.0 82334.0 78502.0 84968.0 90220.0 88493.0 89381.0 75578.0 70840.0 True False 94172.24970607356 101707.46161211231 81242.19736392015 60404.57674380969 73171.65985443961 84578.52913775385 96368.70556634357 75569.2202210506 79572.89878445488 68359.91316201791 1.3775946362435914 1.487823154061918 1.1884479310465228 0.8836257091293621 1.0703884260504766 1.2372533144870541 1.4097253947345254 1.1054610330172028 1.1640286697828506 1.0 16.060862943901043 -5.3387631965934235 5.3935551415965595 1.1363349703425463 1.4316627886532596 0.44649492778135336 0.13441938224650996 0.2025976160782785 10.317344921967312 0.03859999612901692 0.08336335381387129 4.583917612740227e-06 5.3387631965934235 0.2953278183107133 ECINAAPDS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ECINAAPDSPSK 12 0 J3KNN7;Q7Z569 J3KNN7 BRAP BRCA1-associated protein 1 ECINAAPDS(0.998)PS(0.002)K;ECINAAPDS(0.911)PS(0.089)K;ECINAAPDS(0.633)PS(0.367)K;ECINAAPDS(0.96)PS(0.04)K 145.69 3.5406e-07 39020000.0 153235.0 181256.0 141096.0 147885.0 162467.0 123716.0 173972.0 116497.0 119854.0 113248.0 True False 179174.65897079345 199249.8978008272 144460.26374955993 139599.48289963885 130632.75762911797 117228.115170429 157492.11271179366 113439.07718877452 121606.6380085087 133778.96592932518 1.3393335620896532 1.4893963069358005 1.0798428792301895 1.0435084613629666 0.9764820405184673 0.8762821147261677 1.177256167423181 0.8479589926618499 0.9090116459171387 1.0 17.029491773264027 -5.402537700097512 3.261543514262857 0.976280586489111 1.4158695260783192 0.7649559830191976 0.09537099022059457 0.1114350484947261 2.1916813527852494 0.025851789541074838 0.06095715861535525 3.957877059309076e-06 5.402537700097512 0.4395889395892082 ECINAAPDS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 3 ECINAAPDSPSK 12 0 J3KNN7;Q7Z569 J3KNN7 BRAP BRCA1-associated protein 1 ECINAAPDS(0.988)PS(0.012)K;ECINAAPDS(0.629)PS(0.371)K;ECINAAPDS(0.779)PS(0.221)K 160.03 6.7273e-05 104762000.0 123097.0 192577.0 150442.0 160062.0 187675.0 167694.0 183675.0 186986.0 160510.0 144564.0 True False 121341.61420677506 192131.09978839598 138073.23948291384 171833.49343117923 176636.3254832463 160522.118533807 193184.79277132265 195674.05218595394 142431.67355476815 169551.69478057852 0.715661464568706 1.1331712138710148 0.8143430218235105 1.0134578345179837 1.0417844876858129 0.9467444058376594 1.1393857962984586 1.1540672149528266 0.8400486573672582 1.0 17.37136567955696 -5.932015458550759 11.542125012430951 1.0300707717600552 0.9123321073527272 0.1680950506500476 0.12979583722226873 1.1279389765807926 186.92515685749032 0.03499809274814248 0.05193466213670932 1.1694577638643295e-06 5.932015458550759 -0.11773866440732805 ECINAAPDSPS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 ECINAAPDSPSK 12 0 J3KNN7;Q7Z569 J3KNN7 BRAP BRCA1-associated protein 1 ECINAAPDS(0.232)PS(0.768)K 147.39 2.9154e-07 0.0 28978.0 27635.0 28146.0 21818.0 21329.0 30018.0 30863.0 31260.0 31942.0 26245.0 True False 38192.40122015617 36567.473318120894 27772.765649730296 16788.197184739758 18367.836515339226 28140.969714665192 33609.7472104467 26429.485283338145 33630.388909114576 25326.170538356288 1.5080211657863583 1.443861134186858 1.0966034366572972 0.6628794179251918 0.7252512371549138 1.111141918279588 1.3270757677140728 1.0435642152575295 1.3278908020532205 1.0 14.628341329359905 -5.274596508228602 4.199331333214257 1.0236501827357611 1.4879402658578431 0.42980678956029905 0.2035981476953581 0.20303522265610127 8.84836946108211 0.0601520940297395 0.1505699968873459 5.313779044334328e-06 5.274596508228602 0.464290083122082 ECINAAPDSPS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ECINAAPDSPSK 12 0 J3KNN7;Q7Z569 J3KNN7 BRAP BRCA1-associated protein 1 ECINAAPDS(0.224)PS(0.776)K 89.26 0.007588500000000001 8486300.0 25965.0 33452.0 23875.0 23318.0 28288.0 20709.0 26992.0 20611.0 17786.0 18314.0 True False 30360.36166787386 36772.89348343382 24444.270546441698 22011.568057976005 22745.16946710711 19622.983583889036 24435.122354842926 20069.983089159654 18046.086602193827 21634.183226455767 1.4033514161397656 1.699758807555323 1.129891075182795 1.0174439139934224 1.0513532786989042 0.9070360262037858 1.1294682169910615 0.9276977493939637 0.8341468875111417 1.0 14.40102503405618 -5.415599145785198 4.0517926799479875 0.988272535841846 1.5478552851099538 0.8254269771528031 0.10313239992560996 0.08318162077158604 2.3399703444804176 0.027169622380652354 0.05990313263183174 3.840615711366443e-06 5.415599145785198 0.5595827492681078 ECKEVFAFFSHQLLDS(ph)LQK ddPTM_PC-9_AZD4547_30min_R2 1 ECKEVFAFFSHQLLDSLQK 19 1 H0Y7V4;A0A075B6F3;Q96JB1-2;Q96JB1 H0Y7V4 DNAH8 Dynein heavy chain 8, axonemal 1 ECKEVFAFFS(0.007)HQLLDS(0.993)LQK 47.537 0.033114 4985700.0 7858.4 6569.3 9278.5 18926.0 13553.0 13603.0 9111.5 11503.0 9198.7 13731.0 True False 10357.207735125798 8692.697755336765 9155.461027535799 14562.90310378517 11671.399891808935 12752.40225959726 9922.405848685643 9725.475662643588 9684.924502481757 13250.281869391125 0.7816594271138876 0.6560387047627546 0.6909634917794024 1.0990636461422207 0.8808416309067738 0.9624249797323939 0.7488448884704062 0.7339825490890098 0.7309221492755156 1.0 13.693735429583583 ECLNLLNGMT(ph)QK ddPTM_PC-9_Lapatinib_30min_R1 1 ECLNLLNGMTQK 12 0 Q9BTX1-4;Q9BTX1-6;Q9BTX1-5;Q9BTX1-2;Q9BTX1 Q9BTX1-4 NDC1 Nucleoporin NDC1 1 ECLNLLNGMT(1)QK 89.24700000000001 0.023053999999999998 0.0 11834.0 13556.0 12754.0 10184.0 12513.0 11673.0 9938.6 9211.2 13847.0 13407.0 True False 11665.244989910185 13524.611914878156 11705.415351863727 10932.96533282809 11777.009941504526 11173.773001092037 10453.172078056718 9639.185979138834 12287.405044625712 15724.382086295438 0.7418571315484004 0.8601045078054617 0.7444117859528206 0.6952874378673805 0.7489648799470958 0.7106017228384779 0.6647747441323729 0.6130088881228505 0.7814237136437164 1.0 13.94071570485416 -8.548435589666118 22.599621704970495 1.0000000024097542 0.7236128407226 0.6534636876283966 0.060584589564260174 1384.0354297241472 1223885.3856675636 0.0644178721140231 0.016632623068845793 2.828553583499445e-09 8.548435589666118 -0.27638716168715416 ECLPLIIFLR ddPTM_PC-9_Lapatinib_30min_R1 1 ECLPLIIFLR 10 0 P62701 P62701 RPS4X 40S ribosomal protein S4, X isoform 0 156.75 1.3051e-12 0.0 5704.6 6349.1 7960.4 5588.4 6547.6 8891.9 8203.6 9479.2 7613.4 6623.1 False True 5623.251357904486 6334.399049037542 7305.926640032616 5999.389578355902 6162.48304107689 8511.614165031297 8628.342267476923 9919.638237520941 6755.898719343791 7767.894010273979 0.7239093827061822 0.815458995792107 0.9405286208037397 0.7723315444856719 0.7933273848647087 1.0957428298807448 1.110769824622336 1.2770048386861381 0.8697207647797843 1.0 12.9233078005717 -6.763473230907172 24.993379324918862 1.0904681319931866 0.8147214741131084 0.5876987839061333 0.10884817563176993 36.479972777298485 448286.3541203185 0.036655194553356155 0.03394273257072294 1.7239583492935834e-07 6.763473230907172 -0.27574665788007824 ECPDQLGPS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 ECPDQLGPSPK 11 0 E7EWM1;Q15596 E7EWM1 NCOA2 Nuclear receptor coactivator 2 1 ECPDQLGPS(1)PK;ECPDQLGPS(1)PK;ECPDQLGPS(1)PK 123.84 0.00091323 12638500.0 76769.0 89343.0 62278.0 95307.0 76311.0 82302.0 75966.0 76442.0 80130.0 75057.0 True False 101179.94510560327 118221.37755241086 61452.15302827771 73335.4436284715 65716.5348737425 77155.64292945486 82726.82683435793 64629.64536240998 84365.50821136279 72429.2772755729 1.3969481528946124 1.6322319095165343 0.8484435485179517 1.0125110505997583 0.9073200416415821 1.0652549056357346 1.1421738549123688 0.8923138238217189 1.1647984266138114 1.0 16.144285359211466 -5.258838855490895 24.9998540125806 1.0042150189891736 1.5145900619927062 0.7729387543148262 0.1106737087784837 92.60240927047013 890210.5760850791 0.027249295779157842 0.06564435561667248 5.510121109413215e-06 5.258838855490895 0.5103750430035325 ECPDQLGPS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ECPDQLGPSPK 11 0 E7EWM1;Q15596 E7EWM1 NCOA2 Nuclear receptor coactivator 2 1 ECPDQLGPS(1)PK;ECPDQLGPS(1)PK 116.63 0.0012414000000000001 10124900.0 64817.0 72002.0 61586.0 81853.0 77129.0 50527.0 67188.0 58665.0 53517.0 45658.0 True False 75789.23790589563 79149.88271535923 63054.44380620562 77267.04178100667 62016.12612515918 47877.27517230008 60823.466241004244 57125.10591070549 54299.584880783004 53935.4339714709 1.40518453872058 1.4674932022837806 1.1690727071846352 1.4325840378308072 1.1498215840436652 0.8876775738492197 1.1277088504224655 1.0591387090891262 1.006751608033871 1.0 15.718945771617166 -6.451864171005552 4.457547818924588 1.0254244116284088 1.3590418831335802 0.7572229140545265 0.09381242412087239 0.11274914678474009 4.264884092577442 0.029934634771630497 0.03343729712327472 3.5329364786496877e-07 6.451864171005552 0.3336174715051714 ECPDQLGPS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 ECPDQLGPSPK 11 0 E7EWM1;Q15596 E7EWM1 NCOA2 Nuclear receptor coactivator 2 1 ECPDQLGPS(1)PK;ECPDQLGPS(1)PK;ECPDQLGPS(1)PK;ECPDQLGPS(1)PK 150.22 1.7855999999999998e-07 16648900.0 117464.0 126740.0 84905.0 104193.0 119931.0 100243.0 106527.0 104859.0 101284.0 100644.0 True False 115788.94181974084 126446.54131688263 77924.43864277807 111855.70079765872 112876.89437341815 95955.84056784623 112042.44681938572 109731.13194659984 89876.3293521969 118040.1813002995 0.9809281936391523 1.0712160886571072 0.6601518041092703 0.9476069891242611 0.9562582260548573 0.8129082784423236 0.9491890438082666 0.9296082972580237 0.7614045349824353 1.0 16.848918516185535 ECPPHAEQR ddPTM_PC-9_Lapatinib_30min_R1 2 ECPPHAEQR 9 0 J3QT73;A0A087X1P5;J3KQ34;Q9H9Q2-2;Q9H9Q2 J3QT73 COPS7B COP9 signalosome complex subunit 7b 0 ; 99.973 0.0033312 2744600.0 17880.2 17544.2 15974.900000000001 14960.6 17511.7 19859.3 14576.400000000001 16353.099999999999 18611.5 13254.7 False True 17625.225069172902 17503.577482812427 14661.505386897274 16060.852431098581 16481.696235326846 19009.964033289394 15331.094669127036 17112.924725926627 16515.27688221648 15545.757234222425 1.13376433219816 1.125939201229777 0.9431194097526134 1.033134133584836 1.0602054301378157 1.2228393732690528 0.9861915658490518 1.1008099810187593 1.0623655466495872 1.0 13.924233271651406 -8.561975404976653 19.10824578106423 0.9999999961873179 1.0735192149340127 0.0834090039828066 0.07473758355957778 1933.5747208668947 945025.4910361618 0.07324850387708466 0.018912682344321998 2.7417294375205557e-09 8.561975404976653 0.07351921874669476 ECPSDECGAGVFMASHFDR ddPTM_PC-9_AZD4547_30min_R2 4 ECPSDECGAGVFMASHFDR 19 0 P62979;A0A2R8Y422 P62979 RPS27A Ubiquitin-40S ribosomal protein S27a;Ubiquitin;40S ribosomal protein S27a 0 ;;; 175.33 8.574700000000001e-09 57715000.0 116536.0 91055.0 143419.0 198013.0 187619.0 154615.0 115958.0 166214.0 121374.0 144980.0 False True 153592.02390061843 120486.74807242633 141517.1703516902 152364.1621203535 161571.34038967759 144946.8996080001 126278.03735958839 140529.44551774673 127789.58185006803 139904.2943284779 1.0978363790606986 0.8612083614069659 1.0115284239912283 1.0890599380932608 1.1548704860361767 1.0360432487346156 0.9026030113350434 1.0044684203031042 0.9134071435293757 1.0 17.09408072079448 -10.053647782303992 5.047673091019529 0.9999999998990768 1.0080252390412165 0.0007103227437512682 0.08867228859185698 15744626.910647845 15679594.151190192 0.11416815239930403 0.022546051969133223 8.837963786193632e-11 10.053647782303992 0.008025239142139706 ECPSDECGAGVFMASHFDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ECPSDECGAGVFMASHFDR 19 0 P62979;A0A2R8Y422 P62979 RPS27A Ubiquitin-40S ribosomal protein S27a;Ubiquitin;40S ribosomal protein S27a 0 ;;; 145.43 2.2006e-05 40247500.0 149646.0 143620.0 163160.0 183258.0 189622.0 193988.0 176616.0 155686.0 162848.0 137461.0 False True 174978.1121567744 157877.6444484865 167050.35318774576 172990.6483904519 152466.93031291626 183814.927783643 159885.6538908915 151599.40746295213 165229.34392185218 162381.59115932253 1.077573577814573 0.9722631938837394 1.0287517938153619 1.0653341130320628 0.9389422115178168 1.1319936359244744 0.9846291857924824 0.9335997164494383 1.0175374113666342 1.0 17.309028561094586 -7.490797775681433 24.994956246551986 0.977163968664394 1.0319370708306106 0.17467328177702457 0.054293530119208414 1055.719320060199 822535.1417698128 0.021620125725069075 0.0145606691970836 3.2299977835772743e-08 7.490797775681433 0.05477310216621656 ECPSDECGAGVFMASHFDR ddPTM_PC-9_Lapatinib_30min_R1 4 ECPSDECGAGVFMASHFDR 19 0 P62979;A0A2R8Y422 P62979 RPS27A Ubiquitin-40S ribosomal protein S27a;Ubiquitin;40S ribosomal protein S27a 0 ;;; 139.46 1.731e-05 44537500.0 134462.0 134534.0 169184.0 148501.0 160431.0 159952.0 155915.0 144265.0 174133.0 133646.0 False True 132544.5472226892 134222.49478874414 155274.34458912563 159422.25892481417 150994.76399948145 153111.22582632353 163987.51580204593 150968.07856527547 154520.30783821846 156746.53302789852 0.8455979514334666 0.8563027978733958 0.9906078405031716 1.0170703992313463 0.963305287094335 0.9768077345549457 1.0461954892033154 0.9631350413243617 0.9857972923121443 1.0 17.258074007806883 -5.255225393036931 5.7232149565005495 0.9929751765606695 0.8491771982853973 0.8528347670722426 0.023595773972995643 0.052155019784937334 6.966314947335179 0.0061616342100081255 0.015159813553512463 5.5561582523658505e-06 5.255225393036931 -0.1437979782752722 ECS(ph)PTSSLER ddPTM_PC-9_AZD4547_30min_R2 1 ECSPTSSLER 10 0 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 ECS(0.769)PT(0.213)S(0.018)SLER 160.91 0.00055381 31651000.0 53448.0 67155.0 88343.0 122260.0 105430.0 117870.0 88112.0 118340.0 80888.0 100150.0 True False 70443.35221253734 88861.5404623994 87171.51409770922 94074.84589817053 90792.86435426956 110499.57026675924 95953.79730443835 100053.27218266901 85163.5745438752 96643.77898328732 0.7288969135273483 0.9194750184361715 0.9019878466547118 0.9734185364837499 0.939458962691954 1.143369717422453 0.9928605680975255 1.035278972275818 0.8812111388835757 1.0 16.560389247849194 -3.8933205424520896 0.7334076705246756 1.0044075366730283 4.6787816987836904e-20 0.58335098837709 0.06661029914555289 6.425450766414836 1.0048601241220676 0.025869152568595365 7.208906580064854 0.00012784373715642492 3.8933205424520896 -1.0044075366730283 ECS(ph)PTSSLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ECSPTSSLER 10 0 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 ECS(0.643)PT(0.098)S(0.245)S(0.014)LER;ECS(0.97)PT(0.028)S(0.002)S(0.001)LER 116.84 0.0010071 26570900.0 97524.0 117318.0 116134.0 132896.0 146443.0 114311.0 120918.0 113562.0 112123.0 91288.0 True False 114032.88701319974 128964.55571234864 118903.07500064775 125450.26797464553 117748.54539987138 108316.32992698532 109463.77166949082 110581.11782888522 113762.58675912404 107837.79176458956 1.057448276223368 1.1959124310879705 1.1026104397632117 1.163323784007967 1.0919042709713218 1.0044375738279248 1.0150780155852113 1.0254393753748625 1.0549417314429836 1.0 16.718503333757518 -6.594923225674055 4.132898510962436 1.0216670469667777 1.1324020030626651 0.6669949990056737 0.0368053114968953 0.12341860734905455 4.14248860808685 0.01170531322738483 0.011814188255061265 2.541421936932739e-07 6.594923225674055 0.11073495609588746 ECS(ph)PTSSLER ddPTM_PC-9_Lapatinib_30min_R1 2 ECSPTSSLER 10 0 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 ECS(0.934)PT(0.036)S(0.015)S(0.015)LER;ECS(0.89)PT(0.105)S(0.005)SLER 136.81 0.00011605 53457000.0 119882.0 131824.0 153316.0 131550.0 143192.0 146161.0 124964.0 146010.0 154749.0 120416.0 True False 118172.46069633393 131518.76962724258 140710.95029687474 141224.6258379357 134769.72808630363 139910.03474793234 131434.02446645196 152794.1576357109 137319.5380407876 141229.74515576594 0.8367391767647705 0.9312398707665098 0.9963265892867044 0.9999637518440283 0.9542588067241969 0.9906555775033223 0.9306398189806968 1.0818836886463987 0.9723131475549597 1.0 17.107684448805877 -4.840442268696403 2.1527962418708984 0.9907073908474954 0.8064160275114741 0.6188565365075667 0.03729594010387533 0.37346419704870115 2.219597304502874 0.009817226039870668 0.12890498035315853 1.443968540060519e-05 4.840442268696403 -0.18429136333602125 ECSPT(ph)SSLER ddPTM_PC-9_Lapatinib_30min_R1 1 ECSPTSSLER 10 0 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 ECS(0.035)PT(0.844)S(0.114)S(0.007)LER 96.334 0.013621000000000001 5692200.0 48067.0 46733.0 56919.0 43189.0 47401.0 56679.0 45173.0 45416.0 48883.0 40824.0 True False 47381.555765591795 46624.79260976698 52239.339533693834 46365.26313428051 44612.966373951574 54254.9712952022 47511.836906813456 47526.193159259325 43377.281779189616 47880.37400543933 0.9895819894850683 0.9737767003338421 1.091038669158251 0.968356327563634 0.9317589367385357 1.1331359126192018 0.9923029611551488 0.9926027970011311 0.9059511894009401 1.0 15.547146801122535 -8.034701616422177 5.020623214653443 0.9509149717853387 1.0119522236032594 0.12794504810507812 0.06007169082022787 0.39282858340112214 24.882461074906857 0.040346674544728386 0.01552473774691519 9.232055009514096e-09 8.034701616422177 0.061037251817920746 EDAANNYAR ddPTM_PC-9_Lapatinib_30min_R1 1 EDAANNYAR 9 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;F8VQQ4;F8VRZ4;F8VS66;F8VWV9;F8VX09;Q9NY65-2;Q9NY65;C9J2C0;C9K0S6;A6NHL2-2;A6NHL2;P68363;P68363-2;P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8;C9JDL2;Q71U36-2;Q71U36 Q9BQE3;P68363;P68366-2;Q71U36-2 TUBA1C;TUBA1B;TUBA1A;TUBA8;TUBAL3;TUBA4A Tubulin alpha-1C chain;Tubulin alpha-8 chain;Tubulin alpha chain-like 3;Tubulin alpha-1B chain;Tubulin alpha-4A chain;Tubulin alpha-1A chain 0 98.58200000000001 0.020346 111150000.0 29591.0 42746.0 39709.0 48827.0 54913.0 44178.0 45847.0 44334.0 49357.0 42415.0 False True 29169.026913675185 42647.0242633064 36444.27930117271 52417.90046209714 51683.125303111854 42288.60992394792 48220.73332890616 46393.919489224136 43797.894907748334 49746.376235565076 0.5863548085502845 0.8572890628527199 0.7326016899923994 1.053702891118773 1.0389324653191954 0.8500842297275638 0.9693315770492607 0.9326090260230016 0.8804238262572379 1.0 15.602303816212956 -4.257348953374791 0.910330383926353 0.949342640265916 9.648757323295609e-11 0.6149233152156801 0.0852923838022546 3.399946820916536 1.140364533180661 0.029115732046319256 4.020235824753705 5.529056738335316e-05 4.257348953374791 -0.9493426401694284 EDAS(ph)PLPHVCCCK ddPTM_PC-9_AZD4547_30min_R2 2 EDASPLPHVCCCK 13 0 C9J7Z4;Q8NCE0-5;Q8NCE0-3;Q8NCE0-2;Q8NCE0 C9J7Z4 TSEN2 tRNA-splicing endonuclease subunit Sen2 1 EDAS(1)PLPHVCCCK;EDAS(1)PLPHVCCCK 74.789 0.010818000000000001 18335000.0 82399.0 92581.0 105567.0 109801.0 122664.0 121310.0 113874.0 138857.0 100118.0 97468.0 True False 108600.16799432824 122505.99772986982 104167.11260374749 84488.07585853933 105634.22093476348 113724.46652295424 124008.56539683117 117399.84126642629 105410.03308505201 94055.67498695041 1.1546370594798854 1.3024838506221628 1.1075048115725072 0.8982772796033996 1.1231031083389653 1.209118604897926 1.3184591510723465 1.248195191653398 1.1207195429693841 1.0 16.521227373043054 -6.740788856427346 7.513882983160699 1.2035791459964191 1.1145264187087414 0.04334114129119715 0.12138122643956156 0.4312470917969699 105.9583302060666 0.04334538698086483 0.04217921586411983 1.8163985375927417e-07 6.740788856427346 -0.08905272728767777 EDAS(ph)PLPHVCCCK ddPTM_PC-9_Lapatinib_30min_R1 2 EDASPLPHVCCCK 13 0 C9J7Z4;Q8NCE0-5;Q8NCE0-3;Q8NCE0-2;Q8NCE0 C9J7Z4 TSEN2 tRNA-splicing endonuclease subunit Sen2 1 EDAS(1)PLPHVCCCK;EDAS(1)PLPHVCCCK 124.3 0.0011109000000000002 11480000.0 69341.0 90602.0 167985.0 68225.0 102659.0 122012.0 89526.0 89193.0 174481.0 76395.0 True False 68352.18462441798 90392.21663557012 154173.92174085192 73242.49409192834 96620.79945535945 116793.83118386367 94161.21822591781 93337.23239505508 154829.11241361598 89599.773960061 0.7628611279185358 1.0088442486011444 1.7206954317716783 0.8174406123454743 1.0783598572294175 1.3035058686188696 1.0509091046132557 1.0417128109794123 1.7280078461205817 1.0 16.451207472244043 EDAS(ph)SLPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDASSLPPK 9 0 F5H391;B7Z8X0;Q8N468-2;Q8N468 F5H391 MFSD4 Major facilitator superfamily domain-containing protein 4 1 EDAS(0.5)S(0.5)LPPK 68.893 0.041832 197790000.0 38113.0 49846.0 42740.0 43023.0 48408.0 32296.0 39722.0 30858.0 28646.0 34934.0 True False 44564.77813393707 54794.38145926232 43759.08369235261 40612.56079244793 38922.799899735626 30602.340906141308 35959.24459762411 30048.01019675361 29064.893557092353 41267.257662608135 1.0799064599418922 1.3277931358378334 1.0603826416118338 0.9841351980421656 0.9431884284136283 0.7415646844367318 0.8713747080462396 0.7281319840154976 0.7043088201963993 1.0 15.332709949515214 -5.998405765103102 1.1454780438925938 0.7954410564260836 1.2084927375583858 0.6704816640313332 0.10496644372202664 0.2687564582028035 0.7172050289269823 0.03917675864068099 0.07801628322168057 1.0036776073722873e-06 5.998405765103102 0.4130516811323022 EDAVLEYLK ddPTM_PC-9_Lapatinib_30min_R1 2 EDAVLEYLK 9 0 P26038 P26038 MSN Moesin 0 ; 147.51 0.0017416 5162900.0 37644.0 43537.0 39190.0 40259.0 39081.0 32300.0 42264.0 37103.0 37761.0 34863.0 False True 37107.18965693585 43436.19275140529 35967.94947777478 43219.78116008702 36782.33241620226 30918.60429497754 44452.223120659764 38826.94083116081 33507.95853904177 40889.02309797254 0.9075098118148925 1.062294705533306 0.8796480510574545 1.0570020481176536 0.8995649597220653 0.7561590361524344 1.087143192786719 0.9495688057435158 0.819485426657289 1.0 15.31942597460873 EDDDVIVNKPHVS(ph)DEEEEEPPFYHHPFK ddPTM_PC-9_AZD4547_30min_R2 1 EDDDVIVNKPHVSDEEEEEPPFYHHPFK 28 1 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-2;H7C1M2;H7C2G8;J3QSZ5 P18583-10 SON Protein SON 1 EDDDVIVNKPHVS(0.99)DEEEEEPPFY(0.01)HHPFK 42.556999999999995 0.019287000000000002 4402600.0 24069.0 26106.0 26267.0 23086.0 25430.0 27642.0 27225.0 31657.0 28211.0 26530.0 True False 31722.44133369932 34544.25396934553 25918.682417447104 17763.87937514448 21899.48345375202 25913.541370270348 29647.972258186557 26765.138055490563 29702.175866102014 25601.192775103522 1.2391001314809265 1.3493220520154396 1.0124013613401768 0.6938692087979346 0.8554087165442027 1.0122005485412608 1.1580699586395218 1.0454644941980573 1.1601871884261028 1.0 14.643923407377823 -5.2955035789840865 7.5577381604515725 0.9844194766709313 1.294181371804574 0.45601020867558717 0.13176549827697207 0.21081121357184252 41.17952765592482 0.038906530021959096 0.08325883176858923 5.064031762809184e-06 5.2955035789840865 0.3097618951336427 EDDSSASTSQSTR ddPTM_PC-9_Lapatinib_30min_R1 1 EDDSSASTSQSTR 13 0 E7EX17;P23588-2;P23588;F8VX11 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 190.26 8.2346e-05 3037300.0 3488.4 3784.5 5326.7 3747.8 4375.7 4365.3 3474.3 5466.3 3881.3 5735.4 False True 3438.6547763057874 3775.7372227689852 4888.759287656617 4023.425714294296 4118.329928957195 4178.6062950113155 3654.1822541195397 5720.284253709251 3444.147122099069 6726.75624805988 0.5111906317844591 0.5613013291299171 0.7267632581553144 0.5981227156037839 0.6122311820269981 0.6211918703337144 0.5432309599702639 0.850377811052554 0.5120071242498826 1.0 12.715695266023484 -14.522878745222545 0.24602477538887518 3.23655400474879 0.586483328309653 0.5750861347950227 0.0990595418794431 124.22721482867544 1.2326313408027576 139.44803319330654 0.14067599671548212 3.000000000399214e-15 14.522878745222545 -2.650070676439137 EDEEEDDDVVAPKPPIEPEEEK ddPTM_PC-9_AZD4547_30min_R2 1 EDEEEDDDVVAPKPPIEPEEEK 22 1 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E7ESD3;E7EMU4;Q13409;Q13409-7;Q13409-5 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 0 66.63600000000001 0.0034838 1669500.0 5656.1 6634.7 5508.6 2656.0 4577.2 6700.6 6846.3 7503.2 5651.6 4630.7 False True 7454.6221458114915 8779.237026370067 5435.552364744703 2043.7002347909445 3941.734788223111 6281.610422749202 7455.607436959504 6343.752846383322 5950.332038029928 4468.580602475384 1.668230431310108 1.9646589839974649 1.2163934923169253 0.45734885785854024 0.8820999639213345 1.405728346775145 1.6684509244007926 1.4196348708288222 1.331593310576903 1.0 12.12560093196336 -6.938703464928038 24.999987541798177 1.410932509759809 1.224621159015305 0.016958138817069646 0.41135047457157653 298.30258260906413 121661.40288481877 0.1652422673395551 0.14572997257292433 1.151586420589062e-07 6.938703464928038 -0.186311350744504 EDEEEDDDVVAPKPPIEPEEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDEEEDDDVVAPKPPIEPEEEK 22 1 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E7ESD3;E7EMU4;Q13409;Q13409-7;Q13409-5 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 0 64.723 0.044517 0.0 4503.1 7479.7 6346.7 6783.7 6337.6 3571.0 6004.3 6227.3 6308.3 4879.4 False True 5265.385889720885 8222.23518438479 6498.029397993784 6403.631282052139 5095.792774842264 3383.730473613782 5435.52923663246 6063.839973369747 6400.546953368903 5763.996594690849 0.9134956628133284 1.42648161727892 1.1273478898268339 1.110970691403678 0.8840728288312906 0.5870458835333973 0.9430139569546353 1.0520200478527486 1.1104355889565192 1.0 12.492853767845796 -6.120486184760518 3.6591089430762 0.9163056731142862 1.1758458200969821 0.26282781124348353 0.17545928082188061 0.3184284460111528 7.669390142721463 0.056013255399365414 0.0751220320443825 7.577288364160451e-07 6.120486184760518 0.2595401469826959 EDEEEDDDVVAPKPPIEPEEEK ddPTM_PC-9_Lapatinib_30min_R1 2 EDEEEDDDVVAPKPPIEPEEEK 22 1 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E7ESD3;E7EMU4;Q13409;Q13409-7;Q13409-5 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 0 ; 119.38 0.00012749999999999998 0.0 17602.1 21831.0 16381.5 15046.6 17669.9 18625.6 21147.0 18853.8 17125.0 18725.5 False True 17351.090826170202 21780.451660792634 15034.676304418652 16153.177157986174 16630.591222360017 17829.026506394235 22241.88818693433 19729.8163771808 15196.20216575543 21962.177724839636 0.790044186125759 0.9917254988861389 0.6845712885482277 0.7354997924325432 0.7572378035876882 0.8118059479242475 1.012736007585365 0.8983542809084004 0.6919260173624877 1.0 14.422733495689215 -7.026596058392879 24.22519215239201 0.8951389578798894 0.7929037841465159 0.18106380128003963 0.11044102649801385 983.356960474976 895694.0066726888 0.04309572407660618 0.03350642741566202 9.405977631461369e-08 7.026596058392879 -0.10223517373337354 EDEEES(ph)LNEVGYDDIGGCRK ddPTM_PC-9_Lapatinib_30min_R1 2 EDEEESLNEVGYDDIGGCRK 20 1 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 1 EDEEES(1)LNEVGYDDIGGCRK;EDEEES(1)LNEVGYDDIGGCRK 112.47 1.8406e-05 3319700.0 14691.3 13518.900000000001 16850.3 13211.4 13349.2 16410.9 14873.4 17165.4 14792.6 11181.599999999999 True False 14481.799367945545 13487.597817648742 15464.933378038984 14183.010427938447 12564.026301536986 15709.04406267638 15643.47187589488 17962.967149373573 13126.501615016276 13114.324661454546 1.104273360755683 1.0284630101686683 1.1792397837681508 1.0814899580475514 0.9580383760412009 1.1978538329806794 1.1928537900143628 1.3697210960599515 1.0009285231131664 1.0 13.678855895680245 -6.820591106549216 24.999906574560967 1.1779156690852732 1.074648168286247 0.09487488500515873 0.1131297268759546 139.19957680710348 58829.95265458465 0.0386066018913893 0.03404783511448152 1.5115025822079296e-07 6.820591106549216 -0.10326750079902625 EDEEESLNEVGYDDIGGCR ddPTM_PC-9_Lapatinib_30min_R1 1 EDEEESLNEVGYDDIGGCR 19 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 293.29 1.9820999999999994e-120 6243900.0 10057.0 11178.0 8807.0 9891.2 10711.0 10820.0 9173.1 12350.0 8812.5 11907.0 False True 9913.58533577207 11152.118027774277 8082.922456003119 10618.63184407593 10081.000038636228 10357.25382265192 9648.038233676982 12923.826085891604 7819.943450261005 13965.1090849198 0.7098824130544915 0.7985700619995065 0.5787940793625056 0.7603687002733435 0.7218704828823843 0.7416521961748356 0.6908673734668782 0.9254368159463484 0.5599629335302048 1.0 13.769539222458983 -11.709863479785875 2.5296855637998643 1.8147936335553083 0.7258757333289831 0.4183554143579976 0.09859271828354457 11755194.74989814 3369025.466448141 54703987.1409046 0.023308701177446305 1.9504576286050256e-12 11.709863479785875 -1.0889179002263252 EDEGEPGDEGQLEDEGS(ph)QEKQGR ddPTM_PC-9_AZD4547_30min_R2 1 EDEGEPGDEGQLEDEGSQEKQGR 23 1 Q969E4 Q969E4 TCEAL3 Transcription elongation factor A protein-like 3 1 EDEGEPGDEGQLEDEGS(1)QEKQGR 62.858000000000004 0.0014380999999999999 6109900.0 6868.4 6397.1 6540.3 9404.3 7573.1 10312.0 9387.0 7672.7 9997.4 10212.0 True False 9052.40832840502 8464.837472891311 6453.5713486438935 7236.283929986621 6521.705786221365 9667.18900984834 10222.424814971426 6487.060516105837 10525.842153903392 9854.48098829089 0.9186083304804287 0.8589835916218463 0.6548869855563207 0.7343140586079353 0.6618010419798329 0.9809942320995808 1.03733771744222 0.6582853550393748 1.0681275012261136 1.0 13.266564174668884 -6.772723558893427 24.965319963192226 0.9331161093737672 0.7629981408562443 0.3302934349805049 0.12944781810114725 288.7709439914882 638878.2066416071 0.04611556356745466 0.04103173859364473 1.6876269073303176e-07 6.772723558893427 -0.17011796851752292 EDEGEPGDEGQLEDEGS(ph)QEKQGR ddPTM_PC-9_Lapatinib_30min_R1 2 EDEGEPGDEGQLEDEGSQEKQGR 23 1 Q969E4 Q969E4 TCEAL3 Transcription elongation factor A protein-like 3 1 EDEGEPGDEGQLEDEGS(1)QEKQGR;EDEGEPGDEGQLEDEGS(1)QEKQGR 82.089 0.00079091 0.0 16730.8 19578.8 19350.1 17600.3 20296.5 18906.0 18225.0 18943.3 19186.7 16018.5 True False 16492.215723947054 19533.466491517887 17759.209471546055 18894.684774879643 19102.69977445432 18097.434452038553 19168.601324390125 19823.474873916617 17025.69180109194 18787.276381690408 0.8778396287404352 1.0397178438570636 0.9452785550572791 1.0057170816571321 1.0167892027750927 0.9632814296422361 1.0202969783885942 1.055154268834628 0.9062352336331592 1.0 14.197468311904196 -4.7478249041750304 24.997185028638995 0.9957477884791907 0.877839337868804 0.40247243439593094 0.0427072338540675 676.8224438297489 1242624.381153928 0.00998502458908232 0.19554630228676803 1.7872079836870816e-05 4.7478249041750304 -0.11790845061038668 EDEGPPGYPEPLAPGHGS(ph)PFPSLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDEGPPGYPEPLAPGHGSPFPSLSK 25 0 B1AKB5;B0QYS6;B0QYS7;P19484-2;P19484 B1AKB5 TFEB Transcription factor EB 1 EDEGPPGYPEPLAPGHGS(0.651)PFPS(0.326)LS(0.023)K 102.6 5.9544e-07 4420400.0 23386.0 34276.0 33475.0 29883.0 39260.0 31536.0 39857.0 23832.0 28758.0 28659.0 True False 27344.787905445708 37678.69475780757 34273.17095464444 28208.75239199316 31567.284830268123 29882.196644044852 36081.45642030876 23206.435252091243 29178.531345209172 33854.64983548081 0.8077114381135158 1.112954791761545 1.012362293546011 0.8332312556495396 0.9324357210507771 0.8826615188536762 1.0657755019073976 0.6854726120300946 0.8618766251313901 1.0 15.047066376832317 -5.748867583011658 24.990171542203814 0.8896127081689776 0.9912040610196806 0.09001279197375334 0.11817894082841704 472.9479766293988 940116.0977532514 0.0316036631205922 0.05426082115883221 1.7829223000577652e-06 5.748867583011658 0.10159135285070298 EDEGPPGYPEPLAPGHGS(ph)PFPSLSK ddPTM_PC-9_Lapatinib_30min_R1 1 EDEGPPGYPEPLAPGHGSPFPSLSK 25 0 B1AKB5;B0QYS6;B0QYS7;P19484-2;P19484 B1AKB5 TFEB Transcription factor EB 1 EDEGPPGYPEPLAPGHGS(0.871)PFPS(0.093)LS(0.035)K 92.865 2.1669e-06 4600100.0 11757.0 24790.0 23065.0 26774.0 39407.0 36639.0 36664.0 42453.0 36008.0 30862.0 True False 11589.343024030251 24732.600278093065 21168.684733474744 28743.049275445734 37089.15773714288 35072.035379680565 38562.282521670204 44425.52136229604 31952.399858950143 36196.45557896991 0.3201789467685793 0.6832879043677048 0.5848275582478225 0.7940846366224158 1.024662695390861 0.9689356269473349 1.0653607350459706 1.2273445190060877 0.8827494114510606 1.0 15.143560812520992 -5.632589830302831 0.7910592006302496 1.067514870182992 0.3518098635642569 0.809443846325695 0.11031938174675446 0.4099393118233909 0.4172371435263606 0.04894092187727713 0.21159788902402216 2.330291063561219e-06 5.632589830302831 -0.715705006618735 down EDEGPPGYPEPLAPGHGSPFPS(ph)LSK ddPTM_PC-9_AZD4547_30min_R2 2 EDEGPPGYPEPLAPGHGSPFPSLSK 25 0 B1AKB5;B0QYS6;B0QYS7;P19484-2;P19484 B1AKB5 TFEB Transcription factor EB 1 EDEGPPGYPEPLAPGHGS(0.139)PFPS(0.675)LS(0.186)K;EDEGPPGYPEPLAPGHGS(0.323)PFPS(0.566)LS(0.111)K 100.64 8.403499999999999e-07 9674600.0 26336.0 30069.0 39067.0 36279.0 37136.0 51752.0 45704.0 57161.0 49890.0 39841.0 True False 34710.300177170044 39788.216218656664 38548.94605407568 27915.437054962586 31980.30741402024 48515.93925888973 49771.56745962012 48328.08087910721 52527.083547546325 38446.1787166566 0.9028283521486101 1.0349069152461343 1.0026730182517347 0.7260913304465386 0.8318201829552685 1.2619183720818128 1.2945777479325107 1.2570321028594016 1.3662497886893827 1.0 15.230552590987667 -6.767948312689218 24.976627845762824 1.2556840645718348 0.9032572485691593 0.6627332821407859 0.11952359541316186 92.43376044686568 354692.36276502954 0.04253573368463019 0.038393049891040434 1.706285449511733e-07 6.767948312689218 -0.35242681600267545 EDEGPPGYPEPLAPGHGSPFPS(ph)LSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDEGPPGYPEPLAPGHGSPFPSLSK 25 0 B1AKB5;B0QYS6;B0QYS7;P19484-2;P19484 B1AKB5 TFEB Transcription factor EB 1 EDEGPPGYPEPLAPGHGS(0.205)PFPS(0.591)LS(0.203)K 84.32700000000001 6.3013999999999995e-06 5134000.0 19413.0 34275.0 36615.0 31514.0 42471.0 28943.0 41277.0 25436.0 26910.0 28845.0 True False 22699.237475772592 37677.595484416306 37488.04046316078 29748.372749766506 34149.112430624504 27425.178128760483 37366.94374039904 24768.331951669745 27303.507841281687 34074.37016310563 0.6661674850369038 1.105745911195509 1.1001829317376888 0.8730424834668509 1.0021935040078833 0.8048623642192915 1.0966290370601912 0.7268903822171864 0.8012916368104974 1.0 15.056399369787213 -7.773882617216303 24.994886807688463 0.8230683118305637 0.9550961063007414 0.09374164164013465 0.14825900477595005 463.00316044986755 930026.2052669277 0.07711468049277115 0.03745257800447982 1.6831289221585122e-08 7.773882617216303 0.13202779447017765 EDEGPPGYPEPLAPGHGSPFPS(ph)LSK ddPTM_PC-9_Lapatinib_30min_R1 1 EDEGPPGYPEPLAPGHGSPFPSLSK 25 0 B1AKB5;B0QYS6;B0QYS7;P19484-2;P19484 B1AKB5 TFEB Transcription factor EB 1 EDEGPPGYPEPLAPGHGS(0.082)PFPS(0.741)LS(0.177)K 88.09 4.4791e-06 3499400.0 11931.0 19331.0 23808.0 23266.0 30435.0 31816.0 29471.0 35660.0 28567.0 33758.0 True False 11760.861752122559 19286.240257193087 21850.598141537674 24977.059253100793 28644.87313751222 30455.303846718423 30996.864177289535 37316.89378323032 25349.48363615388 39593.025320292494 0.2970437761949653 0.48711206332869866 0.551879983021622 0.6308449291521903 0.7234828080397016 0.7692088088835499 0.7828869839204433 0.9425118055857279 0.6402512420075559 1.0 15.272958688085122 -4.985415859383311 0.3914287812451847 0.8878858546550842 7.978486254472333e-22 0.8086467290830451 0.08704447942909871 2.0541578573239248 0.28095673039415187 0.07162145534369058 0.8474458251885296 1.0341514390361575e-05 4.985415859383311 -0.8878858546550842 down EDEIS(ph)PPPPNPVVK ddPTM_PC-9_AZD4547_30min_R2 2 EDEISPPPPNPVVK 14 0 K7EMU2;K7EMZ6;K7EIE5;K7EID3;K7EJ40;K7EK41;K7EPB2;P10644-2;P10644 K7EMU2 PRKAR1A cAMP-dependent protein kinase type I-alpha regulatory subunit;cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed 1 EDEIS(1)PPPPNPVVK;EDEIS(1)PPPPNPVVK 134.84 1.4019e-05 95155000.0 82292.0 99953.0 107271.0 93054.0 93457.0 120684.0 109023.0 136964.0 103705.0 97624.0 True False 108459.14422006693 132260.85256255252 105848.51645037379 71601.83796996863 80482.10873524596 113137.61040191387 118725.83579446377 115799.36091961383 109186.63458204642 94206.21347443276 1.1512950178121995 1.4039504156320608 1.123583175106605 0.7600543035242694 0.8543184761065523 1.200956988178057 1.260276062647243 1.229211499420273 1.1590173360664717 1.0 16.523534597063986 EDEIS(ph)PPPPNPVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EDEISPPPPNPVVK 14 0 K7EMU2;K7EMZ6;K7EIE5;K7EID3;K7EJ40;K7EK41;K7EPB2;P10644-2;P10644 K7EMU2 PRKAR1A cAMP-dependent protein kinase type I-alpha regulatory subunit;cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed 1 EDEIS(1)PPPPNPVVK;EDEIS(1)PPPPNPVVK;EDEIS(1)PPPPNPVVK;EDEIS(1)PPPPNPVVK 178.22 2.409e-05 119222900.0 443393.0 746925.0 587677.0 478268.0 510598.0 374178.0 492044.0 357921.0 357856.0 361248.0 True False 518450.67748906557 821074.7777446433 601689.4484574344 451472.19452577614 410549.9872584124 354555.4469772769 445434.03022993286 348525.95299864624 363088.96700296155 426739.4027624056 1.2149116630266312 1.9240660047551097 1.4099692799927248 1.0579576003604734 0.9620625248121114 0.8308476899066235 1.043808064937317 0.8167184720757882 0.8508447184688908 1.0 18.702995801627836 -5.760561549041104 2.710848111305591 0.9160665210610116 1.589272569557972 0.704892172885232 0.17483968327514113 0.12854658545877704 1.9279693897021268 0.048267259340968344 0.08650535426896455 1.7355552792416285e-06 5.760561549041104 0.6732060484969603 EDEIS(ph)PPPPNPVVK ddPTM_PC-9_Lapatinib_30min_R1 2 EDEISPPPPNPVVK 14 0 K7EMU2;K7EMZ6;K7EIE5;K7EID3;K7EJ40;K7EK41;K7EPB2;P10644-2;P10644 K7EMU2 PRKAR1A cAMP-dependent protein kinase type I-alpha regulatory subunit;cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed 1 EDEIS(1)PPPPNPVVK;EDEIS(1)PPPPNPVVK 157.35 0.00030391 89922000.0 142397.0 198124.0 177565.0 155076.0 206410.0 201422.0 196110.0 193379.0 175941.0 157729.0 True False 140366.3926675883 197665.25605070198 162966.29112072117 166480.8063583707 194269.36961767368 192807.65059761488 206263.6162264004 202364.09430474718 156124.67183913442 184992.24748931837 0.7587690542312764 1.0685056197401752 0.8809357869449692 0.8999339627352949 1.0501487076040361 1.0422471925951804 1.114985190059439 1.093905809844447 0.8439525112972597 1.0 17.497105287107765 -6.260490745055972 24.93298829504475 1.0343428234362237 0.9124196158944972 0.26407100917155035 0.09844267720105666 116.33819036664603 3057722.112567347 0.02906340517227867 0.03539906510574203 5.489202531355649e-07 6.260490745055972 -0.12192320754172659 EDEVEEWQHR ddPTM_PC-9_AZD4547_30min_R2 4 EDEVEEWQHR 10 0 P15311;E7EQR4 P15311 EZR Ezrin 0 ;;; 166.66 0.0001307 27791300.0 253295.0 271768.0 344355.0 324103.0 313053.0 340872.0 315970.0 410082.0 312638.0 333276.0 False True 333837.54113670613 359611.69128710293 339788.6277024403 249386.0606914344 269590.9946381212 319557.21995393967 344090.7178850026 346713.2496468926 329163.4064168728 321608.10868132015 1.0380258834440772 1.1181673645033632 1.056530039294299 0.7754346173483759 0.8382593204615297 0.993623019221158 1.0699068481073664 1.0780612810681618 1.0234922488942564 1.0 18.29494425597496 -9.434872783324538 13.760732576145225 1.0000028139494355 0.9971907163832934 0.0 0.10333980583509765 0.0 0.0 0.11365878624762998 0.027566304763439912 3.6738990324062473e-10 9.434872783324538 -0.002812097566142091 EDEVEEWQHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EDEVEEWQHR 10 0 P15311;E7EQR4 P15311 EZR Ezrin 0 ;;; 197.21 0.00011785 23068000.0 236799.0 317879.0 282171.0 276384.0 334840.0 219421.0 271631.0 249889.0 225110.0 192080.0 False True 276884.3937065613 349435.9263308766 288899.0267794763 260899.1005290183 269230.5056690524 207914.17649140555 245900.14524186132 243329.67852928178 228401.80788372093 226902.58349555713 1.220278718034001 1.540026212780952 1.2732293406660709 1.1498286908404762 1.186546673561009 0.9163147165994107 1.0837256299758093 1.0723971264701193 1.0066073482508107 1.0 17.79171350995658 -5.942567242708378 1.3506190204025295 1.0320005511364638 1.3862057595807646 0.672975226405929 0.09593037796118375 0.2430926935816 0.8999985858704 0.0329536859994009 0.06425048816040671 1.1413865677057638e-06 5.942567242708378 0.3542052084443008 EDEVEEWQHR ddPTM_PC-9_Lapatinib_30min_R1 4 EDEVEEWQHR 10 0 P15311;E7EQR4 P15311 EZR Ezrin 0 ;;; 166.66 9.8454e-05 27471700.0 155952.0 238834.0 284285.0 249843.0 278615.0 267593.0 262953.0 281556.0 264448.0 231791.0 False True 153728.09588190573 238280.99454691735 260912.1846718344 268217.287671815 262227.4134781656 256148.67117975003 276567.4197010896 294638.11963071243 234663.0814791058 271855.7655079064 0.5654766806019232 0.8764978520935118 0.9597449006989932 0.98661614614171 0.9645828661689325 0.9422226918792365 1.0173314484773957 1.0838030934537728 0.8631896441139891 1.0 18.05248189952505 -4.58600917386402 1.6826390611271163 0.9823809393653942 0.23523769040977752 0.8438036107323871 0.053267369339368764 0.5977533068274372 1.1228164761448742 0.014352211663439432 0.8458695353472118 2.594124564283824e-05 4.58600917386402 -0.7471432489556167 EDFDSTSSSSS(ph)TPPLQPR ddPTM_PC-9_AZD4547_30min_R2 1 EDFDSTSSSSSTPPLQPR 18 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 EDFDSTSSSSS(0.5)T(0.5)PPLQPR 342.02 2.1047999999999986e-222 14224000.0 21113.0 23414.0 28324.0 24144.0 24684.0 23808.0 32838.0 30292.0 27227.0 25607.0 True False 27826.494822318906 30982.11761427474 27948.405253427158 18577.97382108152 21257.052676854688 22319.281996360467 35760.51838436472 25611.067440911025 28666.163634977853 24710.506724164195 1.126099724823029 1.253803410837285 1.1310332712075324 0.7518248827699788 0.8602434953738766 0.9032304454742173 1.4471786751906148 1.0364444455469697 1.1600799593051425 1.0 14.592836975037804 -9.61808725520769 16.23090526911102 1.000134478527267 1.070399222293718 0.013080728893629545 0.19109550104938094 0.0 0.0 0.19957358873898956 0.04840370508555491 2.4094212971001997e-10 9.61808725520769 0.07026474376645098 EDFDSTSSSSS(ph)TPPLQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EDFDSTSSSSSTPPLQPR 18 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 EDFDS(0.001)T(0.003)S(0.016)S(0.021)S(0.021)S(0.068)S(0.435)T(0.435)PPLQPR;EDFDSTS(0.002)S(0.002)S(0.002)S(0.026)S(0.8)T(0.168)PPLQPR 112.43 0.00017873 25915000.0 39506.0 75218.0 67062.0 49193.0 54134.0 41977.0 53871.0 32318.0 41091.0 36416.0 True False 46193.585520932975 82685.14594155582 68661.01241405128 46436.87569585786 43526.831304170526 39775.652223714824 48767.948887735 31469.686743751467 41691.878138465465 43017.932531102604 1.0738216088728654 1.922108782930775 1.596102099151519 1.0794771613508694 1.0118299216890534 0.9246295645416347 1.1336655673183516 0.731548098481916 0.969174381133301 1.0 15.39265056914538 -5.832960620251747 4.13650508303002 0.9626710553008405 1.5724780513869385 0.5822896277135667 0.2149441269002941 0.13688589950489305 4.5377757827599075 0.059627390633592 0.09384359899754824 1.4690594788980917e-06 5.832960620251747 0.609806996086098 EDFDSTSSSSS(ph)TPPLQPR ddPTM_PC-9_Lapatinib_30min_R1 1 EDFDSTSSSSSTPPLQPR 18 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 EDFDSTSS(0.001)S(0.003)S(0.026)S(0.485)T(0.485)PPLQPR 113.95 0.00014645 14982000.0 23590.0 26599.0 24392.0 23713.0 29668.0 31168.0 31533.0 38130.0 27962.0 22152.0 True False 23253.60227412381 26537.411649737704 22386.583915842864 25456.93312424908 27922.98656953221 29835.017296156646 33165.62444784602 39901.659000408654 24812.625107086333 25980.94368431538 0.8950253138095957 1.021418312290106 0.8616539948607632 0.9798309650937489 1.0747487431100986 1.1483423257704053 1.276536558903671 1.5358048377779736 0.9550317112640385 1.0 14.665166213104923 -6.583516967694623 1.764737533183904 1.231222092699739 0.9363774039963948 0.3412970045138082 0.15573304246405278 0.3519649318021016 2.2376829931095275 0.05965580383083316 0.06221825213962609 2.60905378643756e-07 6.583516967694623 -0.29484468870334424 EDFDSTSSSSST(ph)PPLQPR ddPTM_PC-9_AZD4547_30min_R2 1 EDFDSTSSSSSTPPLQPR 18 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 EDFDSTSSS(0.001)S(0.004)S(0.03)T(0.965)PPLQPR 189.52 1.5388999999999997e-10 13559000.0 13296.0 14345.0 15465.0 14609.0 14925.0 20041.0 18893.0 20636.0 19028.0 14458.0 True False 17523.85142601963 18981.740718235735 15259.923995348508 11241.120756800039 12852.9213742528 18787.833101859043 20574.440399409297 17447.180368105113 20033.7812335681 13951.829820672703 1.2560253136154365 1.360519800070247 1.0937578935157004 0.8057094231570864 0.921235532504014 1.3466214355640103 1.4746768462530802 1.2505299012645124 1.435924999879489 1.0 13.76816672741677 -6.786533308781359 24.688658665998723 1.328029277055006 1.0873183695447644 0.23726328319752543 0.18897929174806094 289.70081415571093 285019.7622992347 0.0716125588414558 0.06318300236541244 1.6348077626092724e-07 6.786533308781359 -0.2407109075102416 EDFDSTSSSSST(ph)PPLQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDFDSTSSSSSTPPLQPR 18 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 EDFDST(0.001)S(0.002)S(0.002)S(0.009)S(0.038)S(0.229)T(0.718)PPLQPR 114.06 0.00093964 0.0 5071.9 10925.0 6634.2 5447.3 7099.3 5789.3 6893.9 4836.2 5324.8 4444.8 True False 5930.472495408792 12009.56179919032 6792.384488343605 5142.105441384884 5708.243127751469 5485.698916519815 6240.8598844862045 4709.254874377462 5402.6651264681 5250.607054982559 1.1294832070476644 2.2872711047370906 1.293637938854704 0.9793354154174017 1.0871586976470913 1.0447742249754084 1.1885977791013604 0.8968972206572988 1.0289600935459922 1.0 12.358268515932828 -5.507191482976749 15.475572515463442 1.0448960164132164 1.7289154584237278 0.4994079845600765 0.2686983178937514 3.3453771797867558 3297.8152855849735 0.06502065453030119 0.12725600321698669 3.110344665587435e-06 5.507191482976749 0.6840194420105115 EDFDSTSSSSST(ph)PPLQPR ddPTM_PC-9_Lapatinib_30min_R1 1 EDFDSTSSSSSTPPLQPR 18 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 EDFDSTSSSSS(0.037)T(0.963)PPLQPR 221.34 9.1807e-28 15675000.0 17472.0 28332.0 23389.0 18886.0 24002.0 23207.0 24057.0 25588.0 15959.0 16260.0 True False 17222.846076027614 28266.398994712898 21466.046704150907 20274.93944184912 22590.249549747612 22214.49070815925 25302.553748194972 26776.91189358658 14161.529364279762 19070.519334911896 0.903113636999817 1.4822039451734461 1.1256141653601213 1.0631561252100945 1.1845639414964562 1.1648602913236752 1.326788919789628 1.4040997742818044 0.7425875045969317 1.0 14.219056511700384 -8.268195571131566 24.973954285776326 0.8712937416284595 1.210346327325253 0.3878452603302033 0.16855462986494316 567.1645113643617 2096467.095454716 0.14434362383997743 0.04068949187057495 5.392677252329798e-09 8.268195571131566 0.33905258569679353 EDGAISTIVLR ddPTM_PC-9_Lapatinib_30min_R1 2 EDGAISTIVLR 11 0 P50990-2;P50990;P50990-3 P50990-2 CCT8 T-complex protein 1 subunit theta 0 ; 131.52 0.00071308 4310200.0 25802.0 25869.0 28713.0 30745.0 28391.0 32736.0 32778.0 29531.0 30558.0 26804.0 False True 25434.05874849271 25809.101919886627 26352.327975385215 33006.08986231343 26721.09719885362 31335.957591343195 34475.084456014265 30903.118068215783 27116.236249994417 31437.035685915027 0.8090476151314776 0.8209775939991083 0.8382574056494788 1.0499110091700343 0.8499878126494501 0.9967847447328783 1.0966391615434785 0.9830162861717124 0.8625570337136943 1.0 14.940177566520907 -5.66367250480917 6.861587175473552 0.976533242641709 0.8192876614250518 0.5004636999184411 0.07074697380749177 0.18661976089311974 11.231849099314564 0.01984928750257613 0.034531051140617185 2.1693393556317577e-06 5.66367250480917 -0.15724558121665722 EDGGTVGVFS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EDGGTVGVFSPK 12 0 O43896 O43896 KIF1C Kinesin-like protein KIF1C 1 EDGGT(0.006)VGVFS(0.994)PK;EDGGT(0.097)VGVFS(0.903)PK;EDGGT(0.002)VGVFS(0.998)PK 130.27 0.00015094 18195300.0 103691.0 104918.0 80342.0 103746.0 98560.0 81715.0 102613.0 92175.0 83789.0 73041.0 True False 121243.83830939737 115333.56566109376 82257.65797873166 97933.44796906995 79247.87551887987 77429.72154896395 92892.75378621437 89755.5039174855 85014.25561178566 86282.75510776219 1.405192012679368 1.3366931261878319 0.9533499234696039 1.1350292169826603 0.9184671423612266 0.8973950988498071 1.076608572248263 1.0402484691800356 0.985298342705999 1.0 16.396784623697854 -5.205857434309758 5.051030246365436 1.0029253777617848 1.3835851111456978 0.8237932063525029 0.0685703771321366 0.08085284380245907 4.469404190507152 0.018058720467181984 0.049737118591145046 6.225046009889696e-06 5.205857434309758 0.380659733383913 EDGGTVGVFS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 EDGGTVGVFSPK 12 0 O43896 O43896 KIF1C Kinesin-like protein KIF1C 1 EDGGT(0.307)VGVFS(0.693)PK;EDGGT(0.231)VGVFS(0.769)PK 144.88 0.0001028 23657000.0 202252.0 175399.0 150866.0 163231.0 176265.0 163998.0 151728.0 131855.0 157783.0 147676.0 True False 199367.8493915254 174992.87439198224 138462.37983960105 175235.55226265357 165897.43925032334 156984.18783801023 159583.73342919437 137981.4646603431 140011.8170113512 173201.59983409863 1.1510739484074637 1.010342136328991 0.7994289889482974 1.0117432658272392 0.957828561683197 0.9063668464285418 0.9213756315302621 0.7966523680642028 0.8083748484163062 1.0 17.40209273049487 -4.93858529140008 3.593803178896001 0.8996900445438997 1.1472366599540187 0.5205769846891788 0.07506808338004631 0.19659657238373804 4.849377728102437 0.01979881183335546 0.10425503917386073 1.151899815191973e-05 4.93858529140008 0.24754661541011902 EDGHRNFSCLAVLDLMS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 EDGHRNFSCLAVLDLMSR 18 1 J3QKR4;J3QQX6;J3QRQ1;J3QRT5;P13598 J3QKR4 ICAM2 Intercellular adhesion molecule 2 1 EDGHRNFSCLAVLDLMS(1)R 50.751999999999995 0.031497000000000004 51812000.0 31062.0 12096.0 121130.0 18987.0 29159.0 51230.0 35484.0 37627.0 70006.0 23635.0 True False 30619.050183926825 12067.99245517602 111171.15897532162 20383.367318775236 27443.924948799697 49039.01232296284 37321.18789545457 39375.28778411685 62121.18708413863 27720.278258342092 1.10457225207371 0.4353488930633046 4.010463312786767 0.7353233300477819 0.9900306444629852 1.7690663804287434 1.346349684791609 1.4204506685378355 2.2410015695078385 1.0 14.758654118984005 EDGNEEDKENQGDETQGQQPPQR ddPTM_PC-9_AZD4547_30min_R2 2 EDGNEEDKENQGDETQGQQPPQR 23 1 H0Y449;P67809 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 ; 77.668 0.00038392 16634900.0 30699.0 30640.0 29702.7 22623.1 29249.0 33688.0 38417.0 32802.0 31882.0 34903.0 False True 40460.64342113241 40543.780802143076 29308.822790600574 17407.69381841077 25188.281224490464 31581.48403450065 41836.038576409635 27733.204614973045 33567.217431607 33681.05659364639 1.2012878309988921 1.203756203117193 0.870187154286882 0.5168393031260952 0.7478471215550284 0.937663102898565 1.2421236982304649 0.8234066095243773 0.996620083407334 1.0 15.0396497768167 -7.010170301400171 24.39130973048861 1.0135460345654912 0.8948022837064216 0.05362014887736066 0.21055032323523454 1277.3944070862858 3063560.2128191674 0.08694010489322192 0.0721082629081204 9.768540886622948e-08 7.010170301400171 -0.11874375085906963 EDGNEEDKENQGDETQGQQPPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EDGNEEDKENQGDETQGQQPPQR 23 1 H0Y449;P67809 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 ; 143.69 2.0849000000000004e-08 18011200.0 38931.0 56564.0 39565.0 47209.0 47945.0 34456.0 46607.0 32240.0 35400.0 31491.0 False True 45521.24937770065 62179.300101547014 40508.37965109808 44564.03278364306 38550.521426062274 32649.06670367863 42192.04755454075 31393.734161103628 35917.65802977968 37200.06901738117 1.2236872290863638 1.6714834607563411 1.0889329165537611 1.1979556479538034 1.0363024167522412 0.8776614551017056 1.1341927224604653 0.8439160192534961 0.9655266503134095 1.0 15.18301767752096 -5.7256271066591795 1.2553813743097952 0.9678344477727142 1.4439995289588803 0.5681531889114154 0.1469103209106899 0.33045990982967 1.017987136172487 0.048230187597003336 0.13054062694846394 1.8809311262062963e-06 5.7256271066591795 0.4761650811861661 EDGNEEDKENQGDETQGQQPPQR ddPTM_PC-9_Lapatinib_30min_R1 2 EDGNEEDKENQGDETQGQQPPQR 23 1 H0Y449;P67809 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 ; 143.33 2.685e-08 22958000.0 31081.0 46440.0 41139.0 47621.0 52122.0 45220.0 50502.0 52869.0 42382.0 48968.0 False True 30637.77924044266 46332.47103326512 37756.710221132336 51123.20719899912 49056.286435794704 43286.04601296857 53116.74645181617 55325.486747773495 37608.49285775456 57432.05355424145 0.5334613224565781 0.8067354058567072 0.6574152913664001 0.8901511270307622 0.8541621516191078 0.7536914202813112 0.9248623924208159 0.9633207124575753 0.6548345484849394 1.0 15.809568527544558 -3.9942177407455466 0.6083413570011418 0.8668944038374616 3.545983308793881e-14 0.4198355704158414 0.10980212749576142 8.625219746581243 1.190759011528897 0.04926271449346279 6.487874453255213 0.00010134031718491291 3.9942177407455466 -0.8668944038374262 EDGNEEDKENQGDETQGQQPPQRR ddPTM_PC-9_AZD4547_30min_R2 3 EDGNEEDKENQGDETQGQQPPQRR 24 2 H0Y449;P67809 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 ;; 71.969 0.0022389 33431100.0 37621.4 27084.3 37322.0 60051.0 53964.8 43799.8 35683.2 35685.2 36792.3 53986.0 False True 49584.22262626767 35838.77031264634 36827.08589423841 46207.1697287014 46472.71902025312 41060.99158199723 38858.93567248197 30170.87230431791 38737.06586503084 52095.96657205949 0.9517862108899052 0.6879375251263244 0.7069085827076255 0.8869625187736432 0.8920598287771807 0.7881798588994675 0.7459106381821716 0.5791402730302615 0.7435713053034436 1.0 15.668884058545665 -7.195005734363897 3.993765085199317 0.7316921741944277 0.8159132998048926 0.012449761364343281 0.12384060034725412 0.6136296258318522 19.401597129159157 0.04988632533518118 0.03713837094342591 6.38255058703944e-08 7.195005734363897 0.08422112561046491 EDGNEEDKENQGDETQGQQPPQRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EDGNEEDKENQGDETQGQQPPQRR 24 2 H0Y449;P67809 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 ; 78.917 0.00069777 21184000.0 24560.0 15760.099999999999 23683.0 33738.0 33521.0 35782.0 36245.0 43698.0 31973.0 24881.0 False True 28717.52291788877 17324.658573127643 24247.69253827767 31847.769240071793 26952.80068251191 33905.52892938904 32811.61120892417 42550.97380185816 32440.544638026702 29391.728342112357 0.9770613889603224 0.5894399394099236 0.8249835551023268 1.0835623162194388 0.9170199305324294 1.153573840052452 1.116355282921958 1.4477193483341804 1.1037304189949937 1.0 14.84312257682656 -6.249130707846671 0.9439342198867705 1.2016212766079066 0.7676395133591788 0.46958744242789763 0.15575370018568238 0.45333667558519386 0.8572332216099849 0.07333987449364728 0.11867186462929957 5.634680456141825e-07 6.249130707846671 -0.43398176324872784 EDGNEEDKENQGDETQGQQPPQRR ddPTM_PC-9_Lapatinib_30min_R1 2 EDGNEEDKENQGDETQGQQPPQRR 24 2 H0Y449;P67809 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 ; 94.31299999999999 2.6749e-05 20493500.0 47823.0 25586.0 28141.0 30662.0 25246.9 30410.6 22563.9 20718.4 25506.2 23579.4 False True 47141.035250335895 25526.757188999167 25827.355607401358 32916.985765433514 23761.926979315173 29110.00952857102 23732.14833598937 21681.05250023777 22633.423163806772 27655.067872424435 1.7046074689746615 0.9230408439695981 0.9339104039283326 1.1902695707449653 0.8592250465242498 1.0526103086370417 0.8581482585928958 0.7839811711999627 0.8184186445759958 1.0 14.755256262340586 -4.76087504643083 24.99837534065996 0.9355298740218259 1.7046083454789063 0.8020270479888274 0.1146331311930883 6.073392459910407 268801.7431684571 0.029872028399693117 0.1721844972649802 1.7343029130660256e-05 4.76087504643083 0.7690784714570804 EDGRS(ph)SSGPPHETAAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDGRSSSGPPHETAAPK 17 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 EDGRS(0.333)S(0.333)S(0.333)GPPHETAAPK 53.924 0.027406 4535200.0 6080.8 6982.2 9911.9 8926.7 10807.0 9659.3 8308.3 7072.0 10327.0 9429.2 True False 7110.159338725488 7675.346672247747 10148.237287090074 8426.565939751883 8689.44592869862 9152.749303774173 7521.2776771169765 6886.36749340338 10478.012838235449 11138.639318493872 0.6383328461781003 0.6890739930418701 0.9110841097296868 0.7565166353632585 0.7801173626540928 0.8217116150423818 0.6752420526472328 0.6182413575390401 0.9406905582119387 1.0 13.44328538526528 -8.426305406327954 5.785169555559317 0.9984489546380879 0.7440195271399467 0.5576124876482744 0.08388898982143717 0.164945085275287 7.366238840822386 0.08511834602073148 0.02208493623884955 3.747094049040435e-09 8.426305406327954 -0.25442942749814124 EDGSGDRGDGPFR ddPTM_PC-9_AZD4547_30min_R2 1 EDGSGDRGDGPFR 13 1 P13010 P13010 XRCC5 X-ray repair cross-complementing protein 5 0 72.531 0.0303 13761000.0 14437.0 17090.0 25262.0 28905.0 19455.0 27170.0 22943.0 30940.0 22714.0 26190.0 False True 19027.665691745293 22614.00828683504 24927.009374102436 22241.39882779827 16754.009067744602 25471.05560488551 24984.88255351971 26158.93393046966 23914.61566844996 25273.096071615586 0.7528822601642153 0.8947858316509552 0.9863061218723478 0.8800425070507195 0.6629187425343254 1.0078328168701205 0.9885960344043653 1.0350506268145343 0.9462479626826826 1.0 14.625314791499724 EDGSGDRGDGPFR ddPTM_PC-9_Lapatinib_30min_R1 1 EDGSGDRGDGPFR 13 1 P13010 P13010 XRCC5 X-ray repair cross-complementing protein 5 0 74.611 0.025002 14696000.0 12311.0 17948.0 18925.0 16230.0 18287.0 17199.0 15390.0 17605.0 21413.0 14122.0 False True 12135.442882439103 17906.442508721833 17369.059552612587 17423.608341692845 17211.3946136253 16463.4388628272 16186.818896151668 18422.992570212275 19001.24245111363 16562.96888361782 0.7326852430690782 1.0811130923775882 1.0486682475019353 1.0519616660589315 1.0391491244452453 0.9939908103740347 0.9772897002880807 1.1123001377146928 1.1472123497078757 1.0 14.015673676165186 -4.7579395963658255 24.99998790992028 1.0493254828931518 0.7326847993399974 0.7815762941569251 0.05035190041392272 48.08108390327524 343404.50292867643 0.013314684305022056 0.09463807231846263 1.746064986621834e-05 4.7579395963658255 -0.31664068355315433 EDHS(ph)LEHR ddPTM_PC-9_AZD4547_30min_R2 2 EDHSLEHR 8 0 H3BU36;H3BSM5;P60520 H3BU36 GABARAPL2 Gamma-aminobutyric acid receptor-associated protein-like 2 1 EDHS(1)LEHR;EDHS(1)LEHR 69.01 0.023822 4819800.0 17488.4 18275.1 23956.5 24591.3 22592.0 24024.0 23534.1 23728.1 26934.0 25022.6 True False 23049.347418682435 24182.16868594142 23638.821157100978 18922.155716797646 19455.49076630616 22521.775482214536 25628.589308407263 20061.46736249442 28357.67625314918 24146.566390286687 0.9545600416278803 1.0014744247724203 0.9789723629861529 0.7836375330121206 0.8057249404259985 0.9327113063691843 1.0613761349819386 0.8308207071032857 1.174397874828136 1.0 14.559530433873835 -8.261933318758652 24.99982336609968 1.0871989356070084 0.9203909687199674 0.34489217738236644 0.09288831923221937 52.48301402352482 2655943.286531301 0.07717455664845187 0.024527396742714643 5.470999577530634e-09 8.261933318758652 -0.16680796688704103 EDHS(ph)LEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EDHSLEHR 8 0 H3BU36;H3BSM5;P60520 H3BU36 GABARAPL2 Gamma-aminobutyric acid receptor-associated protein-like 2 1 EDHS(1)LEHR;EDHS(1)LEHR 80.014 0.016828 1913200.0 12211.2 17199.7 21339.2 16489.1 25721.7 17946.2 17017.4 16773.3 15773.3 15902.5 True False 14278.314977806322 18907.172547142687 21848.00745736666 15565.269185383477 20681.717529768408 17005.06967952048 15405.388676693226 16333.01864778039 16003.954672348129 18785.497365879266 0.7600711708458946 1.0064770806379832 1.1630252333403712 0.8285790299944468 1.1009406419727439 0.9052232873220254 0.8200681822071187 0.8694482945895595 0.8519313787995123 1.0 14.197331692909412 -6.985625749941618 24.86198803958811 0.8727916422933806 0.9790762481278414 0.10539134395300953 0.11809303954682236 419.6649328629064 725857.7919647634 0.0406557017059982 0.03584049567164529 1.0336517638406875e-07 6.985625749941618 0.10628460583446087 EDIFYTSK ddPTM_PC-9_Lapatinib_30min_R1 4 EDIFYTSK 8 0 A0A0A0MSS8;P42330;S4R3Z2;S4R3D5;A6NHU4;P17516;B4DK69;P52895;H0Y804;S4R3P0;P52895-2;Q04828 A0A0A0MSS8;B4DK69;Q04828 AKR1C3;AKR1C1;AKR1C4;AKR1C2 Aldo-keto reductase family 1 member C3;Aldo-keto reductase family 1 member C4;Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 ;;; 135.83 0.016225999999999997 96742000.0 792000.0 744770.0 778060.0 745480.0 725980.0 717770.0 726560.0 653970.0 696510.0 658780.0 False True 780705.9347649874 743045.5308235314 714090.9101984532 800305.0860483772 683279.2837315963 687072.6503035929 764177.7217146159 684355.833634859 618061.7092245441 772649.2452308263 1.0104273570237607 0.9616854418870869 0.9242109723217564 1.0357935259605267 0.8843330760356454 0.8892426344095273 0.9890357447852297 0.8857263989566313 0.7999253387478561 1.0 19.55945410591059 -6.281545815851767 24.90914103029144 0.9054397156024515 0.977303456698482 0.27154393015170963 0.059783523448695995 1119.7722624633695 1387241.7176507292 0.01855688951085477 0.02106741206758893 5.229427954755895e-07 6.281545815851767 0.07186374109603044 EDILENEDEQNS(ph)PPK ddPTM_PC-9_AZD4547_30min_R2 1 EDILENEDEQNSPPK 15 0 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 EDILENEDEQNS(1)PPK 157.12 2.7562e-14 0.0 13277.0 17946.0 10197.0 11983.0 12248.0 12064.0 14142.0 13525.0 13931.0 13456.0 True False 17498.809821244173 23746.693546842685 10061.781117398566 9220.504485504474 10547.57661586924 11309.636172886954 15400.610603315856 11435.022023581194 14667.364219299816 12984.909535687635 1.3476266255957015 1.828791604714491 0.7748826504909285 0.7100938562693028 0.8122949633865646 0.8709830547377807 1.186039114172411 0.8806393292269968 1.129569996540071 1.0 13.664548342516909 -5.266769931079603 24.997996826483227 0.9126271035313621 1.588209129236408 0.6914514862749366 0.17833384840109856 214.2880636810149 1004923.220807651 0.04725428835003005 0.10318780717835518 5.410408652061659e-06 5.266769931079603 0.6755820257050459 EDILENEDEQNS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDILENEDEQNSPPK 15 0 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 EDILENEDEQNS(1)PPK 84.41 0.0061146 2690400.0 9527.5 17178.0 8364.5 12322.0 10388.0 7817.9 14560.0 7212.7 9924.9 8752.3 True False 11140.317573297449 18883.318314552987 8563.941402542896 11631.638288462995 8352.545970881954 7407.915561373609 13180.771394728537 7023.37426748735 10070.032886433914 10339.022706831322 1.077501993098118 1.8264123070429257 0.8283124667947994 1.125022994753421 0.8078661018282861 0.716500560200817 1.2748566057427828 0.6793073645971184 0.9739830515876826 1.0 13.335812201310349 -5.281946298505325 24.97431851241354 0.9221821586701388 1.4519572047528801 0.43392257434698245 0.24038902754376298 585.8830420228414 713515.9118450597 0.05863177915430935 0.12227054510433927 5.224607884629375e-06 5.281946298505325 0.5297750460827414 EDILENEDEQNS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 3 EDILENEDEQNSPPK 15 0 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 EDILENEDEQNS(1)PPK;EDILENEDEQNS(1)PPK;EDILENEDEQNS(1)PPK 186.75 4.0649999999999996e-38 0.0 24128.0 63063.0 40209.0 48850.0 48363.0 48575.0 57455.0 52256.0 38253.0 46061.0 True False 23783.930295466693 62916.98149807919 36903.1712312285 52442.59195882289 45518.383425316395 46497.560483855574 60429.7387705259 54684.004529907 33944.544318052125 54022.58247757546 0.4402590399179695 1.1646422405703347 0.6831063888244671 0.970753147178619 0.8425806641918846 0.8607059927791588 1.1186014440462935 1.012243436392662 0.6283399045601413 1.0 15.721274987158976 -4.74125725363727 24.84891591296841 0.9165909411822346 0.4402572289135015 0.43631358912650453 0.16357938092921664 1292.7307388630743 1591565.2087006753 0.038837483465531085 1.5670149349894753 1.8144405634408476e-05 4.74125725363727 -0.4763337122687331 EDILENEDEQNS(ph)PPKK ddPTM_PC-9_Lapatinib_30min_R1 2 EDILENEDEQNSPPKK 16 1 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 EDILENEDEQNS(1)PPKK;EDILENEDEQNS(1)PPKK 85.61 0.0021485 10931500.0 47012.0 69404.0 85897.0 64031.0 79776.0 81447.0 85819.0 80332.0 72367.0 68504.0 True False 46341.60025905505 69243.29930216906 78834.88023200884 68740.05334115437 75083.7325256506 77963.70167223019 90262.2879044081 84064.51798638415 64216.266401706394 80344.82512415778 0.5767838835599286 0.8618264984106518 0.9812066938995062 0.8555629218799042 0.93451858796908 0.9703636986172038 1.1234362358113887 1.0462966078584188 0.7992582758438053 1.0 16.29391748486689 -4.398480077216941 1.3393784605175063 0.97196951794818 2.8402682080423796e-15 0.6457900965061589 0.0862226538616698 2.107235983764571 1.7026169345276219 0.026214113202918263 3.575332763321031 3.9950288764476125e-05 4.398480077216941 -0.9719695179481771 EDITHTYK ddPTM_PC-9_AZD4547_30min_R2 1 EDITHTYK 8 0 P21980;P21980-2 P21980 TGM2 Protein-glutamine gamma-glutamyltransferase 2 0 95.741 0.0053157 5702800.0 81883.0 115560.0 104600.0 73485.0 89291.0 108400.0 121000.0 147780.0 123830.0 100420.0 False True 107920.09072779513 152912.5101010332 103212.93565557421 56544.16858193246 76894.48592485135 101621.73086380535 131768.76559194006 124943.99664656763 130375.4009960446 96904.32636546911 1.1136767033577086 1.5779740269214857 1.065101420408337 0.5835050993356001 0.7935093179931741 1.0486810514583715 1.3597820709777364 1.2893541633564276 1.345403305362665 1.0 16.56427345681699 -7.199344358714775 7.3636587613410365 1.2724194729994531 1.0249325847783937 0.14665724732319674 0.25527259625954624 0.5684991646224198 59.61538062763816 0.1105120142965332 0.08525381210106321 6.319106011299723e-08 7.199344358714775 -0.24748688822105946 EDITHTYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EDITHTYK 8 0 P21980;P21980-2 P21980 TGM2 Protein-glutamine gamma-glutamyltransferase 2 0 ; 104.01 0.0032438000000000002 9345900.0 124066.0 189516.0 156486.0 125429.0 145673.0 98021.0 149577.0 82849.0 100378.0 90641.0 False True 145067.92338480428 208329.8960123893 160217.2197164598 118401.61977630475 117129.42137238046 92880.60620389156 135407.98371629897 80674.30153577174 101845.83835348072 107073.495786239 1.354844374133606 1.9456719376034763 1.4963294001002514 1.1057976477454436 1.0939161041890055 0.867447219518432 1.2646265326633848 0.7534479092457158 0.9511769239028607 1.0 16.708241884217934 -5.748713425040732 2.7297552553617512 0.9902753701718804 1.667296138161058 0.6933551556493538 0.1837642981077869 0.1362822521174025 2.0715637280744734 0.05147207497301743 0.09298925941228778 1.7835552817838844e-06 5.748713425040732 0.6770207679891777 EDITHTYK ddPTM_PC-9_Lapatinib_30min_R1 2 EDITHTYK 8 0 P21980;P21980-2 P21980 TGM2 Protein-glutamine gamma-glutamyltransferase 2 0 ; 136.8 0.0028232 16913100.0 171996.0 292240.0 254190.0 257020.0 290130.0 281250.0 316710.0 328510.0 244220.0 278020.0 False True 169543.30549979687 291563.3362351725 233291.47940177462 275922.1081935855 273065.1238175268 269221.5931257719 333107.6941260688 343773.7738847166 216713.37184938925 326075.3865616362 0.5199512520327844 0.8941592903089604 0.7154525886230203 0.8461911556805882 0.837429426050564 0.8256421803700982 1.0215665084034282 1.0542769802704353 0.6646112548836162 1.0 18.314846019400413 -3.8151357258215683 0.46699568675339825 0.9239967398281675 2.6508481026709083e-16 0.3853190271984026 0.1255226090701783 12.827715566242574 1.0842348562908155 0.07850197633630744 7.912285229475308 0.00015306090406024412 3.8151357258215683 -0.9239967398281673 EDITQSAQHALR ddPTM_PC-9_AZD4547_30min_R2 2 EDITQSAQHALR 12 0 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 0 ; 182.23 0.00016119 8136900.0 38607.0 33683.0 94894.0 137768.0 104008.0 96550.0 63173.0 106167.0 70682.0 93330.0 False True 50883.22292451413 44570.371043034786 93635.64355736194 106007.71609438196 89568.28450876275 90512.71323708858 68795.27461768295 89761.32962495726 74418.10621983714 90062.54510744105 0.5649765156404636 0.494882428537458 1.039673522946285 1.1770455295030686 0.9945120294114643 1.0049983944947425 0.7638610982580263 0.9966554855614567 0.8262936177415293 1.0 16.458639627404665 -5.259260196793343 24.99488378705597 0.9766497043757592 0.5299294294548076 0.7314780921270523 0.10795426160253757 96.78639580373148 1110105.6948259186 0.029822873158998637 0.07136468222868934 5.504777924391764e-06 5.259260196793343 -0.44672027492095157 EDITQSAQHALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EDITQSAQHALR 12 0 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 0 ; 117.27 0.00053594 7510000.0 28893.0 35184.0 53097.0 53077.0 69457.0 55936.0 56173.0 45486.0 44346.0 36123.0 False True 33784.014237237774 38676.83499704463 54363.03385149387 50103.26776795577 55847.39945124647 53002.617690299776 50851.88678269823 44292.04069640077 44994.47635561046 42671.81395048932 0.7917173213315055 0.9063789751689504 1.2739799136397034 1.1741536890390671 1.308765535865064 1.2420990059573502 1.1916973307415517 1.0379694837391105 1.0544308336134023 1.0 15.380995819400674 -5.108184433447071 4.4391773841012805 1.1708166806491975 0.8148980656740025 0.6207325325372179 0.09860623764825334 0.1375403900369355 4.338544058192775 0.026874308748452754 0.08110917548565673 7.794990074906224e-06 5.108184433447071 -0.35591861497519506 EDITQSAQHALR ddPTM_PC-9_Lapatinib_30min_R1 2 EDITQSAQHALR 12 0 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 0 ; 171.49 0.00092969 9213800.0 50303.0 64967.0 88834.0 58416.0 85439.0 97621.0 66303.0 72023.0 91574.0 60829.0 False True 49585.669995559576 64816.57290306058 81530.41142915648 62712.107510063455 80413.64599953694 93445.97739566561 69735.84491692936 75369.45151288823 81259.97180302991 71343.21160045247 0.695029966876976 0.908517733488879 1.142791438739203 0.8790199670470922 1.1271380162962406 1.3098089544804423 0.9774699421645756 1.056434800482268 1.1390007539626172 1.0 16.122488541467945 -4.299672700151261 1.0497041622925214 1.0896204621703585 1.6254436526356915e-17 0.5341460434860796 0.1113239828174827 3.41687680426646 1.5349219853968163 0.035666883192954836 5.309795532414896 5.015650886099318e-05 4.299672700151261 -1.0896204621703585 EDIYAVEIVGGATR ddPTM_PC-9_Lapatinib_30min_R1 1 EDIYAVEIVGGATR 14 0 A0A087WYC1;P34932;A0A087WTS8 A0A087WYC1 HSPA4 Heat shock 70 kDa protein 4 0 136.27 0.00024367 3084500.0 8222.7 9428.7 8814.2 9278.3 10245.0 9993.8 8497.0 6897.8 10988.0 7254.9 False True 8105.442790141504 9406.868424447603 8089.530499795924 9960.657133501469 9642.409242444977 9566.38847068565 8936.93308385969 7218.296969656925 9750.4157312304 8508.8997984534 0.9525841157060952 1.1055328711424501 0.9507140395831548 1.1706163392959386 1.133214571900072 1.1242803061829993 1.0503041868566947 0.8483231840347846 1.14590792725079 1.0 13.054756888027265 -10.345509794082236 5.157673006324449 0.9999999545595492 1.0537475919088166 0.025306907737705497 0.09959137391272097 5.2248102502051316e-08 1.2017269511756674e-08 0.0967321116571786 0.023460963234899032 4.513258470575814e-11 10.345509794082236 0.05374763734926746 EDKLECSEELGDLVK ddPTM_PC-9_Lapatinib_30min_R1 1 EDKLECSEELGDLVK 15 1 A0A087WVQ6;Q00610-2;Q00610;A0A087WX41;P53675-2;P53675 A0A087WVQ6 CLTC;CLTCL1 Clathrin heavy chain;Clathrin heavy chain 1;Clathrin heavy chain 2 0 76.311 0.018247 4568200.0 13858.0 10946.0 14455.0 16787.0 13686.0 11608.0 13225.0 13477.0 13515.0 14949.0 False True 13660.382378754039 10920.655209520233 13266.565697913606 18021.57197979038 12881.01638771127 11111.552899569637 13909.725789578013 14103.190620207375 11992.798380740709 17532.91473170959 0.7791278625252317 0.622865928262881 0.756666298839635 1.0278708506576502 0.7346762694519348 0.6337538891621689 0.7933493091380427 0.8043836883949878 0.6840162382727406 1.0 14.097778234142682 -11.862840858602146 2.1444147130846525 2.2793488326986093 0.7612852114169891 0.3086873185401998 0.10788691577550079 7201466.235233962 804857.0273251105 44698896.78863496 0.02936511208704291 1.371384199481833e-12 11.862840858602146 -1.51806362128162 EDKS(ph)PETGTAGGSSTASYSAGR ddPTM_PC-9_AZD4547_30min_R2 1 EDKSPETGTAGGSSTASYSAGR 22 1 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 EDKS(0.858)PET(0.11)GT(0.026)AGGS(0.004)S(0.001)TASYSAGR 46.347 0.028348 6831900.0 18169.0 22134.0 16809.0 14233.0 15479.0 21916.0 21285.0 17518.0 22098.0 20726.0 True False 23946.364061322984 29288.382646039026 16586.1016771945 10951.80174765794 13330.008036988896 20545.58905545347 23179.323765491303 14810.995623593013 23266.055166038874 20000.389048503414 1.1972949127764512 1.4643906463524825 0.8292889521784379 0.5475794356349003 0.6664874370524484 1.0272594700847009 1.158943644010053 0.7405353759706633 1.1632801296822686 1.0 14.287740443193824 -5.268162868795345 24.859947481600127 0.8764617269809736 1.3308427886842105 0.4287535794421339 0.20215998934706558 416.7605516710491 1540967.4771420292 0.055962479141071816 0.1209199992803265 5.393083335740564e-06 5.268162868795345 0.4543810617032369 EDKS(ph)PETGTAGGSSTASYSAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDKSPETGTAGGSSTASYSAGR 22 1 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 EDKS(0.898)PET(0.065)GT(0.037)AGGSSTASYSAGR 60.797 0.0033108000000000005 7517000.0 16331.0 21403.0 16686.0 23400.0 23388.0 12485.0 21632.0 15949.0 11027.0 13258.0 True False 19095.515748047295 23527.748392500725 17083.857522007387 22088.973863823594 18805.2892921628 11830.264621413618 19582.860357882393 15530.355649362353 11188.24901396555 15661.570449729741 1.2192593207264735 1.5022598447594842 1.0908138220776058 1.4103932894037945 1.200728199801145 0.7553689880198293 1.2503765456177685 0.9916218618823343 0.714375933746709 1.0 13.934941264364786 -6.568953863108842 7.913883770934605 0.9618118755286833 1.3046485171180005 0.505978470772237 0.17110405574556137 0.20644368302025984 30.80175623817612 0.0550512776168397 0.05517102772555998 2.6980260396370905e-07 6.568953863108842 0.34283664158931715 EDKS(ph)PETGTAGGSSTASYSAGR ddPTM_PC-9_Lapatinib_30min_R1 2 EDKSPETGTAGGSSTASYSAGR 22 1 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 EDKS(0.831)PET(0.152)GT(0.016)AGGSSTASYSAGR;EDKS(0.877)PET(0.111)GT(0.012)AGGSSTASYSAGR 79.021 0.00028632 11730100.0 30348.4 56996.0 39983.0 46005.0 53192.0 43135.0 51530.0 51956.0 46024.0 47371.0 True False 29915.62625078505 56864.02926382384 36695.752078843296 49388.36116818109 50063.35113949563 41290.21660259618 54197.97126177357 54370.06543470314 40840.292465794315 55559.01423211019 0.5384477508151214 1.023488808247419 0.6604824183081902 0.8889351593217651 0.9010842224511904 0.7431776314478346 0.9755027516389949 0.9786002539130743 0.7350795011440425 1.0 15.761733381765398 -4.7441444325289766 24.92845252810808 0.8708385733203583 0.5384467134371459 0.4203515747711133 0.11948716261965503 1026.3313972611722 1479244.0607181548 0.028234670484328435 0.8304722388953814 1.802418214213533e-05 4.7441444325289766 -0.3323918598832124 EDKS(ph)PSEESAPTTSPESVSGSVPSSGSSGR ddPTM_PC-9_AZD4547_30min_R2 1 EDKSPSEESAPTTSPESVSGSVPSSGSSGR 30 1 A0A494C0B4;P54725-2;P54725-3;P54725 A0A494C0B4 RAD23A UV excision repair protein RAD23 homolog A 1 EDKS(0.772)PS(0.127)EES(0.1)APTTSPESVSGSVPSSGSSGR 61.953 0.00030529 122970000.0 28783.0 37439.0 39012.0 21155.0 26033.0 41681.0 47271.0 41115.0 40587.0 40955.0 True False 37935.39527640817 49540.42459045157 38494.675390012046 16278.041591491863 22418.76731228967 39074.68048094344 51478.027423938875 34761.621478709145 42732.34595999728 39521.17791573182 0.9598751170143536 1.2535158920638212 0.9740265199608039 0.4118814886084713 0.5672595933271929 0.9887023247196625 1.3025428425666306 0.8795694691294086 1.0812518303759164 1.0 15.270338326164854 -6.988601909226341 24.97275838953255 1.0686362508460365 0.8347530632542498 0.1805763353140427 0.23582126395778544 437.2786548646589 958055.6802646901 0.09397579225616876 0.08281240645041958 1.0265925086807014e-07 6.988601909226341 -0.23388318759178672 EDKS(ph)PSEESAPTTSPESVSGSVPSSGSSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EDKSPSEESAPTTSPESVSGSVPSSGSSGR 30 1 A0A494C0B4;P54725-2;P54725-3;P54725 A0A494C0B4 RAD23A UV excision repair protein RAD23 homolog A 1 EDKS(0.468)PS(0.318)EES(0.212)APT(0.001)T(0.001)SPESVSGSVPSSGSSGR;EDKS(0.686)PS(0.295)EES(0.019)APTTSPESVSGSVPSSGSSGR 81.02 3.8699e-07 103075000.0 41901.0 69811.0 43883.0 59727.0 53554.0 41353.0 62830.0 36039.0 41455.0 48883.0 True False 48994.01171752676 76741.37471517388 44929.33714720424 56380.6898275466 43060.478140605715 39184.37588220407 56878.28755019191 35093.01443647688 42061.20094984513 57745.100942384895 0.848453131399155 1.3289677126331894 0.7780631848238075 0.9763718290803641 0.7456992444011702 0.6785748962721571 0.9849889708729084 0.60772280009504 0.728394275244434 1.0 15.817410933940765 -5.295563329381669 24.961727069814632 0.8033143704595328 1.0887105270180546 0.3021136892865832 0.16747330938226104 586.3481238625027 428913.63762965397 0.04171640621180174 0.08684590301485574 5.063335099346098e-06 5.295563329381669 0.2853961565585218 EDKS(ph)PSEESAPTTSPESVSGSVPSSGSSGR ddPTM_PC-9_Lapatinib_30min_R1 3 EDKSPSEESAPTTSPESVSGSVPSSGSSGR 30 1 A0A494C0B4;P54725-2;P54725-3;P54725 A0A494C0B4 RAD23A UV excision repair protein RAD23 homolog A 1 EDKS(0.608)PS(0.265)EES(0.126)APT(0.001)TSPESVSGSVPSSGSSGR;EDKS(0.739)PS(0.165)EES(0.095)APTTSPESVSGSVPSSGSSGR;EDKS(0.607)PS(0.271)EES(0.122)APTTSPESVSGSVPSSGSSGR 71.126 2.6575999999999998e-05 130056000.0 20973.4 25065.5 23435.4 21820.4 27428.6 26627.800000000003 25245.3 32994.7 25596.4 22578.9 True False 20674.315469949495 25007.462374769733 21508.63187526009 23425.14500672055 25815.30367470241 25488.99106643353 26552.37810779842 34527.75421507427 22713.46388995868 26481.632780506894 0.7807039558817476 0.9443323446875113 0.8122094303449663 0.8845808414035474 0.9748380656386502 0.9625158417420527 1.0026714866065056 1.3038378147321081 0.8577063234060869 1.0 14.692704456819913 -6.636591277722109 1.1950193880318005 1.0615569235950464 0.852557084524025 0.34047587175245675 0.11243311869598561 0.489421813861504 1.4771052303136623 0.052096905831588027 0.05292918094292322 2.3089191314821168e-07 6.636591277722109 -0.20899983907102138 EDKSPSEES(ph)APTTSPESVSGSVPSSGSSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDKSPSEESAPTTSPESVSGSVPSSGSSGR 30 1 A0A494C0B4;P54725-2;P54725-3;P54725 A0A494C0B4 RAD23A UV excision repair protein RAD23 homolog A 1 EDKS(0.175)PS(0.054)EES(0.769)APT(0.001)TSPESVSGSVPSSGSSGR 60.48 0.00045498 87433000.0 39247.0 46598.0 40918.0 51740.0 51124.0 34508.0 50146.0 31207.0 32809.0 34138.0 True False 45890.741936416154 51223.94148454652 41893.640302379135 48841.17554334328 41106.61919670472 32698.339732137887 45395.807854399536 30387.84931654965 33288.769556470106 40326.94916374069 1.1379671135072638 1.2702161345397207 1.0388497312870648 1.2111299405524585 1.019333722216335 0.8108309805279805 1.1256940779248539 0.7535370254061367 0.8254720539683461 1.0 15.299456645872777 -6.489920798351041 4.291455562294037 0.9015455347061898 1.1610602914250756 0.5448594077910534 0.11239861877447634 0.16515327368600247 6.913860529130634 0.03617572071159051 0.03942250830598207 3.236526756125888e-07 6.489920798351041 0.2595147567188858 EDKSPSEESAPTT(ph)SPESVSGSVPSSGSSGR ddPTM_PC-9_AZD4547_30min_R2 1 EDKSPSEESAPTTSPESVSGSVPSSGSSGR 30 1 A0A494C0B4;P54725-2;P54725-3;P54725 A0A494C0B4 RAD23A UV excision repair protein RAD23 homolog A 1 EDKSPSEESAPT(0.009)T(0.535)S(0.452)PES(0.004)VSGSVPSSGSSGR 121.45 1.9528e-17 33722000.0 15728.0 14520.0 20965.0 15669.0 18281.0 20924.0 18621.0 24214.0 18045.0 16938.0 True False 20729.176837277126 19213.3060459242 20686.99040171236 12056.754133636776 15742.998703029509 19615.618972271775 20278.23292634314 20472.282682365632 18998.821860402368 16345.005775525948 1.2682269509085018 1.1754848122900683 1.265645952397756 0.7376414728277338 0.9631687451956824 1.2000986259449997 1.2406378562867548 1.2525099693154973 1.1623625051788045 1.0 13.996562266432614 -6.822021341623968 24.997936371516193 1.1912488389632194 1.0782919617325912 0.06540049425389194 0.15924839377826375 187.394567531286 77322.54113678141 0.06030796690740872 0.05318665039186716 1.5065330319707855e-07 6.822021341623968 -0.1129568772306282 EDKSPSEESAPTT(ph)SPESVSGSVPSSGSSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDKSPSEESAPTTSPESVSGSVPSSGSSGR 30 1 A0A494C0B4;P54725-2;P54725-3;P54725 A0A494C0B4 RAD23A UV excision repair protein RAD23 homolog A 1 EDKSPSEESAPT(0.005)T(0.569)S(0.402)PES(0.014)VS(0.005)GS(0.003)VPS(0.001)SGSSGR 99.10799999999999 1.4593e-12 27555000.0 40292.0 44287.0 40174.0 42172.0 62379.0 39507.0 49452.0 31544.0 41110.0 41401.0 True False 47112.63979672532 48683.52067741346 41131.90052074344 39809.23956346874 50156.28274139825 37435.18337190131 44767.54855852446 30716.003423630675 41711.15597752098 48906.67356986433 0.963317199020371 0.9954371688736487 0.8410283815763007 0.8139837911200464 1.025550892757996 0.765441209540131 0.9153668669485968 0.6280534164678394 0.8528724800294507 1.0 15.57774372139829 -6.781925324503454 24.999691663708198 0.8142888906081778 0.92046680493922 0.1489810538554357 0.1092759494586197 422.4407254005617 515515.33344030404 0.03770429892370025 0.03328952146521468 1.652245872006303e-07 6.781925324503454 0.10617791433104218 EDKSPSEESAPTTS(ph)PESVSGSVPSSGSSGR ddPTM_PC-9_AZD4547_30min_R2 1 EDKSPSEESAPTTSPESVSGSVPSSGSSGR 30 1 A0A494C0B4;P54725-2;P54725-3;P54725 A0A494C0B4 RAD23A UV excision repair protein RAD23 homolog A 1 EDKSPSEESAPTT(0.168)S(0.832)PESVSGSVPSSGSSGR 154.48 1.1552e-15 35205000.0 35745.0 35682.0 42664.0 51141.0 38961.0 49765.0 44890.0 49007.0 45173.0 36682.0 True False 47111.16645781226 47215.508700459184 42098.24748383764 39351.23257057367 33551.93766581329 46653.18668300062 48885.123036547084 41434.094218827646 47560.75255749271 35397.77434513182 1.3309075875356937 1.3338552938414512 1.1892908032402134 1.1116866328062112 0.9478544424482331 1.3179694923225234 1.3810225061020016 1.170528231940266 1.3436085583734911 1.0 15.1113710324514 -11.686810674848008 2.535441728984471 0.4001137816804814 1.2303640601259598 0.23431981067921592 0.127741844443892 11783697.582409576 2650650.8442041306 41496610.783618815 0.03528038140980415 2.056787030703993e-12 11.686810674848008 0.8302502784454784 EDKSPSEESAPTTS(ph)PESVSGSVPSSGSSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDKSPSEESAPTTSPESVSGSVPSSGSSGR 30 1 A0A494C0B4;P54725-2;P54725-3;P54725 A0A494C0B4 RAD23A UV excision repair protein RAD23 homolog A 1 EDKSPSEESAPT(0.004)T(0.269)S(0.719)PES(0.005)VS(0.003)GSVPSSGSSGR 138.51 6.6943e-15 21962000.0 20948.0 23950.0 21194.0 19564.0 23182.0 22848.0 22783.0 20429.0 19266.0 14878.0 True False 24494.08265814063 26327.597719964146 21699.345338692583 18467.892507343786 18639.653513379424 21649.810658394737 20624.829305364026 19892.7603963147 19547.728802308917 17575.263625816813 1.3936680086073112 1.4979916250753005 1.2346526231798758 1.0507889327028792 1.0605618163245698 1.2318341914708297 1.1735146478865681 1.1318612807089647 1.1122296210450404 1.0 14.101258709177621 -5.439916036373061 3.877578490253788 1.120591695642341 1.4426961546971755 0.797391567494068 0.06706657388509961 0.09855901726273213 2.7336812577158014 0.018483681189977064 0.04051990727147213 3.6314825666931694e-06 5.439916036373061 0.32210445905483454 EDKSPSEESAPTTS(ph)PESVSGSVPSSGSSGR ddPTM_PC-9_Lapatinib_30min_R1 2 EDKSPSEESAPTTSPESVSGSVPSSGSSGR 30 1 A0A494C0B4;P54725-2;P54725-3;P54725 A0A494C0B4 RAD23A UV excision repair protein RAD23 homolog A 1 EDKSPSEESAPT(0.003)T(0.368)S(0.628)PESVSGSVPSSGSSGR;EDKSPSEESAPTT(0.336)S(0.636)PES(0.024)VS(0.002)GS(0.001)VPSSGSSGR 146.87 4.6157e-16 70840000.0 133463.0 127589.0 135572.0 107720.0 127138.0 127884.0 118267.0 123614.0 127194.0 104072.0 True False 131559.7931458833 127293.57550954455 124425.79348305408 115642.08814338608 119659.99280292523 122414.69943216421 124390.28657512454 129357.55771509354 112868.07230780122 122060.70653277692 1.0778226415603747 1.0428710362688458 1.0193763170594303 0.9474145400947089 0.9803318053938429 1.0029001380496863 1.0190854215785 1.059780509138354 0.9246880139719066 1.0 16.897239320840512 -5.170082030373811 2.2416913983390008 0.994277420210392 1.073706611640656 0.3825334828920095 0.03556815578653191 0.38721565772807937 3.4887349863451425 0.009918969753444234 0.04325882840722315 6.759552876036125e-06 5.170082030373811 0.07942919143026395 EDLES(ph)SGLQR ddPTM_PC-9_AZD4547_30min_R2 1 EDLESSGLQR 10 0 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 EDLES(0.5)S(0.5)GLQR 119.34 0.00079819 6270800.0 41416.0 51257.0 55424.0 60109.0 72794.0 62162.0 67483.0 82422.0 65892.0 57876.0 True False 54585.426493684456 67824.82286473397 54689.04154660171 46251.798724792476 62687.809615903505 58275.00031324594 73488.85626810677 69685.57376913946 69374.91659881592 55849.77885608336 0.977361551141376 1.2144152448572543 0.9792167966775177 0.8281464971235882 1.1224361295581984 1.043424011819492 1.3158307476467672 1.2477323132954368 1.2421699426525008 1.0 15.769263947744816 -7.171795291234639 6.871443689630392 1.2216263601883752 1.0278683836504077 0.3246973286684285 0.12157239331830959 0.2855337763159145 18.689182625572755 0.04695683231047182 0.03627976863261608 6.732939448972178e-08 7.171795291234639 -0.19375797653796756 EDLESS(ph)GLQR ddPTM_PC-9_Lapatinib_30min_R1 2 EDLESSGLQR 10 0 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 EDLES(0.024)S(0.976)GLQR;EDLES(0.148)S(0.852)GLQR 160.72 0.0005442 14084700.0 89214.0 108510.0 123039.0 93921.0 109295.0 85151.0 81407.0 85068.0 100900.0 67557.0 True False 87941.79200015632 108258.75176183436 112923.20836427469 100828.26365127115 102866.48298223749 81509.29022667599 85621.85613248973 89020.56983600228 89535.57947589627 79234.13743595598 1.109897764347326 1.366314511208488 1.4251837909581484 1.2725356382249942 1.2982596430154016 1.0287142999765597 1.08061826509687 1.1235128281412359 1.1300126734927458 1.0 16.273834518169494 -6.75212636784269 24.881954572053584 1.0807940811061343 1.3044782763691727 0.6331936195345836 0.08414363313082003 123.61605684285561 330269.5382240098 0.028418520319300342 0.0280436784815292 1.7695939798413616e-07 6.75212636784269 0.2236841952630384 EDLFIVSK ddPTM_PC-9_Lapatinib_30min_R1 1 EDLFIVSK 8 0 O60218;C9JRZ8;C9JRZ8-2 O60218 AKR1B10;AKR1B15 Aldo-keto reductase family 1 member B10;Aldo-keto reductase family 1 member B15 0 112.84 0.017156 18830000.0 157070.0 152360.0 166500.0 141120.0 165120.0 158650.0 148200.0 146820.0 144670.0 155140.0 False True 154830.15299688998 152007.21978097054 152811.01270858626 151498.43556251973 155407.96623841027 151864.90933121322 155873.0708518307 153641.7931927613 128375.74115736289 181955.74228894373 0.8509220486761082 0.8354076539095135 0.839825172793525 0.8326114562624898 0.85409761892331 0.8346255381709987 0.8566537603650122 0.8443910110227784 0.7055327825461184 1.0 17.473228055932736 -10.713328376593314 4.920527130449084 1.0000175401057505 0.8311709805720958 0.6002643400271304 0.041990102279872724 7.862229212121455e-06 1.2935448158059686e-06 0.03956262725703462 0.009594350207302156 1.9349583595555092e-11 10.713328376593314 -0.16884655953365468 EDLPAENGET(ph)KTEESPASDEAGEK ddPTM_PC-9_Lapatinib_30min_R1 1 EDLPAENGETKTEESPASDEAGEK 24 1 A6NL93;A6NEL0;P05114 A6NL93 HMGN1 Non-histone chromosomal protein HMG-14 1 EDLPAENGET(0.747)KT(0.048)EES(0.183)PAS(0.022)DEAGEK 57.692 0.00443 6749700.0 10772.0 27047.0 13040.0 16076.0 25848.0 22362.0 26038.0 30766.0 22334.0 20952.0 True False 10618.38930465714 26984.374333262742 11967.901535855657 17258.28266796391 24327.67145912324 21405.62938836804 27386.12023508754 32195.500676804924 19818.509732553674 24573.52528321489 0.43210687853199886 1.0981075780646987 0.4870242017750059 0.7023120398501511 0.9899951748372228 0.8710850047628005 1.1144563069179907 1.3101702057700395 0.8064984370024776 1.0 14.58481721908859 -6.507580487814789 1.6136531389417015 1.062717453861406 0.694332552078537 0.3691698090708776 0.21106170909409988 0.4093814416247324 2.1639227200491145 0.08080403676808232 0.08980212906655935 3.1075599251551434e-07 6.507580487814789 -0.368384901782869 EDLPAENGETKTEES(ph)PASDEAGEK ddPTM_PC-9_AZD4547_30min_R2 1 EDLPAENGETKTEESPASDEAGEK 24 1 A6NL93;A6NEL0;P05114 A6NL93 HMGN1 Non-histone chromosomal protein HMG-14 1 EDLPAENGET(0.071)KT(0.029)EES(0.887)PAS(0.013)DEAGEK 63.726000000000006 0.009057700000000002 0.0 15394.0 17982.0 8987.9 10530.0 10829.0 12882.0 16177.0 13805.0 14399.0 10677.0 True False 20288.971784908703 23794.329842824332 8868.714573410469 8102.471186878248 9325.580272146302 12076.486503575083 17616.72166099849 11671.754457341109 15160.101743858882 10303.20147982587 1.9691910154950787 2.309411292151735 0.8607727016477169 0.7864032556039255 0.9051148121684514 1.1721100987126558 1.7098298713747198 1.1328279351029802 1.471397193730807 1.0 13.330805070492707 -5.257765682942607 24.991298781497342 1.1364876205442942 2.139301234036774 0.6789675731339727 0.2776298456176047 187.87352511501038 1278045.7007618593 0.0781617081449795 0.19082253090505108 5.523753847305123e-06 5.257765682942607 1.0028136134924799 EDLPAENGETKTEES(ph)PASDEAGEK ddPTM_PC-9_Lapatinib_30min_R1 1 EDLPAENGETKTEESPASDEAGEK 24 1 A6NL93;A6NEL0;P05114 A6NL93 HMGN1 Non-histone chromosomal protein HMG-14 1 EDLPAENGET(0.015)KT(0.019)EES(0.96)PAS(0.006)DEAGEK 79.635 7.1274e-05 7823900.0 17460.0 41875.0 26939.0 32704.0 43802.0 34380.0 49604.0 56392.0 30512.0 38153.0 True False 17211.017198228146 41778.041010292356 24724.17940754719 35109.16125734583 41225.65247804537 32909.647543694366 52172.25240576397 59012.17818911735 27075.41725439587 44747.69521432309 0.38462354576687 0.9336355941952472 0.5525240861932335 0.784602672588775 0.921291080592898 0.735448996558832 1.165920438044469 1.3187758141837975 0.605068420277642 1.0 15.449525756038149 -6.3839598959760755 0.9605252398740054 1.0249041339650735 0.6324407276488966 0.31093406422201497 0.22514365411735887 0.684438875866359 1.3571571859764602 0.11026574221251549 0.15175071316149882 4.130856457668837e-07 6.3839598959760755 -0.39246340631617693 EDLPAENGETKTEESPAS(ph)DEAGEK ddPTM_PC-9_Lapatinib_30min_R1 1 EDLPAENGETKTEESPASDEAGEK 24 1 A6NL93;A6NEL0;P05114 A6NL93 HMGN1 Non-histone chromosomal protein HMG-14 1 EDLPAENGET(0.113)KT(0.015)EES(0.113)PAS(0.759)DEAGEK 45.913000000000004 0.023462 6705400.0 3907.4 9625.3 6210.6 7655.1 8652.3 7016.1 10587.0 11330.0 7568.9 6076.1 True False 3851.6797594705986 9603.013209226674 5699.988441609291 8218.081590664993 8143.388725076291 6716.037758327921 11135.143057411147 11856.43316219853 6716.410777949562 7126.345789105668 0.5404845447380363 1.3475368012463256 0.7998473004668245 1.1531971411250217 1.14271591164232 0.9424237831112545 1.5625319605503691 1.6637465417863861 0.9424761268555351 1.0 12.7989467732027 -7.245090537086338 24.874921070266943 1.3475008796152645 1.0100869693336092 0.19561400736005197 0.29194185374606646 1093.1495059162971 1663239.6123549528 0.10681564098220779 0.08248948925266152 5.68734354805903e-08 7.245090537086338 -0.33741391028165535 EDLQELNDR ddPTM_PC-9_AZD4547_30min_R2 1 EDLQELNDR 9 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 91.265 0.036557 6765700.0 26035.0 27972.0 31859.0 34438.0 39259.0 37821.0 34143.0 41035.0 35220.0 33324.0 False True 34313.58843835895 37013.40197772673 31436.528843699194 26498.851161796134 33808.56550966773 35456.04689114372 37181.660856244736 34693.98364049202 37081.65729694491 32157.33690303619 1.0670531748889682 1.1510095531023916 0.9775849579363353 0.8240374892267338 1.0513484251388876 1.1025803224332322 1.1562419166847788 1.0788823634589073 1.1531320957564675 1.0 14.972860314801768 -6.525544640285617 15.587197973904061 1.1034248335509642 1.0039415561561602 0.20336893297051428 0.08673662214501188 1.287844330228444 7491.955435055415 0.030631234185736905 0.031159601313385868 2.981641055085599e-07 6.525544640285617 -0.099483277394804 EDLQELNDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDLQELNDR 9 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 100.02 0.009425 0.0 24030.0 22958.0 24632.0 27907.0 31085.0 25627.0 28818.0 20891.0 28537.0 28817.0 False True 28097.80438586592 25237.11851586375 25219.320297380204 26343.461265714737 24994.117395539615 24283.075006244842 26088.150415747732 20342.633385844187 28954.29963830008 34041.29398475352 0.8254035348494806 0.7413677790029661 0.7408449369955055 0.773867799429525 0.7342293570489425 0.713341714246256 0.766367765791516 0.597586959971477 0.8505640135556592 1.0 15.054998257639875 -8.527819238473489 24.449162445955437 1.0000000033784486 0.7374124917845851 0.69365775069264 0.054843377914076584 219.40519266047212 1085778.857745342 0.050935705292301 0.013151542544611632 2.966065664923107e-09 8.527819238473489 -0.2625875115938635 EDLQELNDR ddPTM_PC-9_Lapatinib_30min_R1 1 EDLQELNDR 9 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 99.65299999999999 0.018761 7646800.0 22075.0 25117.0 25502.0 24187.0 24967.0 26897.0 34526.0 26917.0 25647.0 26048.0 False True 21760.206451940798 25058.843129683893 23405.324000566794 25965.79266546674 23498.4901470106 25746.67800996937 36313.58734298457 28167.662085339605 22758.364785117057 30550.362093221716 0.7122732747173818 0.8202470089624162 0.7661226380606398 0.8499340396108703 0.7691722302769128 0.8427617954708907 1.1886467084146788 0.9220074707916223 0.7449458279961438 1.0 14.89890185900424 -7.014828097391929 24.822916084951615 0.9657297186813812 0.7900742423667831 0.3904978364564964 0.10633943437691286 686.6742156709668 1149522.8469766206 0.04035732823415575 0.03242040015077084 9.664333373059363e-08 7.014828097391929 -0.1756554763145981 EDLRLPEGDLGK ddPTM_PC-9_AZD4547_30min_R2 2 EDLRLPEGDLGK 12 1 I3L397;I3L504;P63241;P63241-2 I3L397 EIF5A Eukaryotic translation initiation factor 5A;Eukaryotic translation initiation factor 5A-1 0 ; 96.06700000000001 0.0057028 14933100.0 95185.0 113923.0 108417.0 103804.0 98882.0 138162.0 121759.0 141527.0 123142.0 112526.0 False True 125451.85002900696 150746.3818643129 106979.3197415907 79873.5915558129 85153.9411275622 129522.7082989398 132595.31512156207 119657.25411692246 129651.03472062429 108586.49899024852 1.1553172005322043 1.388260817561219 0.9851990876987189 0.7355757142790454 0.784203763077483 1.1928067439633672 1.2211031422375045 1.1019533296461481 1.193988533807204 1.0 16.728485212471853 EDLRLPEGDLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EDLRLPEGDLGK 12 1 I3L397;I3L504;P63241;P63241-2 I3L397 EIF5A Eukaryotic translation initiation factor 5A;Eukaryotic translation initiation factor 5A-1 0 ;; 101.71 0.0034156 31296300.0 218973.0 342190.0 300329.0 329394.0 309676.0 312107.0 338560.0 232680.0 321175.0 252456.0 False True 256040.80398611017 376160.3617450738 307489.98236407473 310939.12208975636 248997.2108277668 295739.55948702793 306489.1458378636 226572.39654483873 325871.5767715959 298224.27435940405 0.8585511844604018 1.2613338151398947 1.0310695969487182 1.0426351870841641 0.8349327410138606 0.9916683010539187 1.0277136108259892 0.7597382776151405 1.0927064118827323 1.0 18.186038166909356 -6.0302812632549285 20.803170596564964 0.9444074053518022 1.0656587436513278 0.11802454600319934 0.1275628161704688 150.3851443157067 103314.36787372241 0.03564750983084099 0.0461567393106567 9.326500905824592e-07 6.0302812632549285 0.12125133829952561 EDLRLPEGDLGK ddPTM_PC-9_Lapatinib_30min_R1 2 EDLRLPEGDLGK 12 1 I3L397;I3L504;P63241;P63241-2 I3L397 EIF5A Eukaryotic translation initiation factor 5A;Eukaryotic translation initiation factor 5A-1 0 ; 101.72 0.0034125999999999996 48554000.0 333999.0 356080.0 382710.0 343280.0 415030.0 365370.0 366850.0 366490.0 375060.0 320780.0 False True 329236.1130120845 355255.51863748935 351245.06110332225 368525.9563485104 390618.7513803741 349743.9768190698 385843.6979891646 383518.4633375231 332816.7932431085 376226.39558751823 0.8751010478622764 0.9442599530602297 0.933600260967376 0.9795324322553638 1.038254508353622 0.9296104178785934 1.0255625403066893 1.0193821269201953 0.8846184030319804 1.0 18.521241544582693 -4.627483881446672 0.9410318397853442 0.9843146624909866 0.798321574251428 0.33448915250237155 0.04512636033300948 3.0595708128770025 1.7689099745627035 0.015009259039127816 0.6232774426863813 2.3578497043743803e-05 4.627483881446672 -0.18599308823955862 EDLS(ph)PAFDHSPNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDLSPAFDHSPNK 13 0 K7EIY0;K7ENP9;K7EIE9;D3DUJ3;K7EQG9;P17706-3;P17706-2;P17706-4;P17706 K7EIY0 PTPN2 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 2 1 EDLS(0.71)PAFDHS(0.29)PNK 112.36 0.00046425 8268200.0 38686.0 55580.0 47143.0 39487.0 39716.0 30182.0 45193.0 32435.0 32138.0 27527.0 True False 45234.77571667122 61097.6150845765 48267.06791082312 37274.67140858127 31933.93490369154 28599.20278762564 40911.99187101424 31583.615617723208 32607.95745087739 32517.427196387907 1.3910933187757233 1.8789191013046485 1.4843446137148486 1.1462982967090891 0.9820560129443088 0.8795038615724952 1.2581558689722787 0.9712827348539915 1.002784053422884 1.0 14.988925494347152 -5.746579680236781 2.8558389324498896 1.0226261882361756 1.6448817813015284 0.7629039955533414 0.14329051964504788 0.11209453029613924 1.8675659189852303 0.03996475385821501 0.07157678274733359 1.7923396806943755e-06 5.746579680236781 0.6222555930653528 EDLSKS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 EDLSKSPK 8 1 B1ALK7;A0A2R8YG42;Q14155-1;Q14155-5;Q14155-6;Q14155-2;Q14155-3;Q14155;E9PDQ5 B1ALK7 ARHGEF7 Rho guanine nucleotide exchange factor 7 1 EDLS(0.002)KS(0.998)PK 92.866 0.036681 0.0 24654.0 20008.0 23794.0 26866.0 25067.0 26054.0 23749.0 20802.0 23264.0 27958.0 True False 32493.459164943415 26475.194722234966 23478.47601327659 20672.45877556231 21586.87973791592 24424.83926130612 25862.614992090814 17587.528882405626 24493.68754560269 26979.198929752914 1.2043893241436952 0.9813187853045507 0.8702436300799246 0.7662369379234804 0.8001304929076195 0.9053211448161338 0.9586131545058322 0.6518921828701865 0.907873047282765 1.0 14.719559891763343 -4.819837725401946 1.914827244389703 0.8442224276415549 1.297200594015794 0.5532894893173195 0.09520119054814892 0.5173528840285107 2.1706559939321792 0.025390735075265587 0.4118053687460223 1.5141268978880589e-05 4.819837725401946 0.45297816637423916 EDLSPAFDHS(ph)PNK ddPTM_PC-9_AZD4547_30min_R2 4 EDLSPAFDHSPNK 13 0 K7EIY0;K7ENP9;K7EIE9;D3DUJ3;K7EQG9;P17706-3;P17706-2;P17706-4;P17706 K7EIY0 PTPN2 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 2 1 EDLSPAFDHS(1)PNK;EDLSPAFDHS(1)PNK;EDLSPAFDHS(1)PNK;EDLS(0.031)PAFDHS(0.969)PNK 142.4 4.6113000000000004e-05 87893800.0 388712.0 423892.0 448624.0 359537.0 385231.0 490984.0 504485.0 493991.0 486094.0 394555.0 True False 512314.3302881265 560906.7993401451 442674.9526342858 276651.2994412772 331748.3252210908 460282.692863787 549383.1876830581 417656.0417338925 511787.936459431 380741.749543195 1.345569092180695 1.4731948886958361 1.16266459658127 0.7266114098944939 0.8713211136396642 1.2089104843795653 1.4429286736802442 1.096953623381167 1.344186543959159 1.0 18.538453249108457 -5.349960141435361 5.48126172006356 1.1011530564254937 1.4075528938148072 0.27068677644012584 0.2001186766372566 0.3025461169911364 14.352793873275493 0.0585719710782165 0.12572100325795116 4.467245896414013e-06 5.349960141435361 0.30639983738931353 EDLSPAFDHS(ph)PNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 EDLSPAFDHSPNK 13 0 K7EIY0;K7ENP9;K7EIE9;D3DUJ3;K7EQG9;P17706-3;P17706-2;P17706-4;P17706 K7EIY0 PTPN2 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 2 1 EDLS(0.002)PAFDHS(0.998)PNK;EDLSPAFDHS(1)PNK;EDLSPAFDHS(1)PNK;EDLS(0.006)PAFDHS(0.994)PNK;EDLSPAFDHS(1)PNK 106.35 0.00063906 84292500.0 474265.0 655752.0 560745.0 519796.0 543410.0 370240.0 581381.0 410733.0 346169.0 390902.0 True False 554548.697339272 720850.7248460085 574115.2874372562 490673.5153213705 436932.7114013246 350823.9626297302 526308.3828460622 399951.69395758654 351231.0667375938 461769.4382214716 1.2009211771899508 1.561062004498179 1.243294250153259 1.062594175160713 0.9462140090608705 0.7597383750231423 1.1397644349811578 0.8661285499924394 0.7606199927183965 1.0 18.816813167286035 -5.8106009094426065 2.0646125704570895 0.910588803182823 1.3859582524214855 0.671228716143583 0.13379078322989918 0.17692984946054394 1.5402690107158072 0.040278591323243386 0.07491586911374898 1.5466750882494262e-06 5.8106009094426065 0.47536944923866253 EDLSPAFDHS(ph)PNK ddPTM_PC-9_Lapatinib_30min_R1 4 EDLSPAFDHSPNK 13 0 K7EIY0;K7ENP9;K7EIE9;D3DUJ3;K7EQG9;P17706-3;P17706-2;P17706-4;P17706 K7EIY0 PTPN2 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 2 1 EDLSPAFDHS(1)PNK;EDLS(0.038)PAFDHS(0.962)PNK;EDLSPAFDHS(1)PNK;EDLS(0.002)PAFDHS(0.998)PNK 133.32 2.5696999999999998e-05 130948200.0 246267.0 534397.0 458567.0 502927.0 641874.0 522852.0 594764.0 575594.0 483375.0 539665.0 True False 242755.18742016342 533159.6365797538 420865.39137980924 539913.9292952896 604120.2332928377 500490.8387875417 625557.9697173976 602338.1985492052 428932.21733559255 632945.3761915894 0.38353260257751315 0.8423469964940057 0.6649316152874706 0.8530182060005449 0.9544587195309151 0.7907330673603746 0.9883285244634512 0.9516432558105622 0.6776765159680335 1.0 19.271721473461824 -4.489569563948437 1.074341602892428 0.8812442740768028 2.119227521505265e-33 0.5807166096422371 0.11807711793775122 2.221539509847197 1.3922371530043929 0.03587621989068318 2.5910016209200135 3.239145346498584e-05 4.489569563948437 -0.8812442740768028 EDLVGPEVGAS(ph)PQSGR ddPTM_PC-9_AZD4547_30min_R2 1 EDLVGPEVGASPQSGR 16 0 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 EDLVGPEVGAS(0.992)PQS(0.008)GR 126.8 2.6863e-05 9755100.0 24893.0 34939.0 41615.0 37390.0 37127.0 40862.0 42804.0 57405.0 43815.0 39817.0 True False 32808.45619343459 46232.34848061611 41063.15790924203 28770.31316974149 31972.556908668936 38306.89268041336 46613.47307766455 48534.37628566941 46130.97144990466 38423.01894935157 0.85387502311263 1.203246120289471 1.068712428957512 0.748778049108164 0.8321198537474241 0.9969776901421701 1.2131652939377164 1.2631588462542835 1.2006076750687797 1.0 15.229683257536438 -7.18781802742477 4.672400885622447 1.1912202603026847 0.9497107271653377 0.3819833625955871 0.1359670444297314 0.2409158288295459 9.923372322087305 0.05760554429540536 0.043670309418947506 6.48906273083664e-08 7.18781802742477 -0.24150953313734702 EDLVGPEVGAS(ph)PQSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EDLVGPEVGASPQSGR 16 0 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 EDLVGPEVGAS(0.985)PQS(0.015)GR;EDLVGPEVGAS(0.842)PQS(0.158)GR 97.77600000000001 0.0021416 17757100.0 70984.0 106004.0 106594.0 94483.0 112807.0 71663.0 88097.0 66733.0 58527.0 59295.0 True False 83000.18920209353 116527.37656397015 109135.60521999636 89189.423828019 90703.27814182534 67904.86612449847 79751.8143929532 64981.32945945805 59382.846652794215 70044.71412103836 1.1849600679170154 1.6636141360018835 1.5580848118161827 1.273321262670846 1.294933947265295 0.9694502572622083 1.1385843370727564 0.9277121089704115 0.8477848385558364 1.0 16.095988562266932 -6.543837398894626 1.1508342391958184 0.9513762411868396 1.4816989005984553 0.6932242194029352 0.14130775518033967 0.2594101203905316 0.7260081802171354 0.06603472509550408 0.07370125758647246 2.8586606338180467e-07 6.543837398894626 0.5303226594116157 EDLVGPEVGAS(ph)PQSGR ddPTM_PC-9_Lapatinib_30min_R1 1 EDLVGPEVGASPQSGR 16 0 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 EDLVGPEVGAS(0.993)PQS(0.007)GR 102.36 0.0015119999999999999 8278700.0 24012.0 54554.0 46009.0 49507.0 56848.0 40864.0 45390.0 47902.0 43988.0 34836.0 True False 23669.584476738495 54427.68356478774 42226.317619876 53147.90993051064 53504.31240746823 39116.34197863659 47740.072105024294 50127.701794848515 39033.60822582482 40857.35618394774 0.5793224693779362 1.3321391457573455 1.0335058741873784 1.3008161783946188 1.3095392703967785 0.9573879866951556 1.1684572024212538 1.2268953862105978 0.9553630452760562 1.0 15.31830823208581 -4.750072501828499 24.972092764273587 1.1515285627578324 0.5793212025731002 0.5888996260117128 0.141032956432334 340.3886412293061 747757.7653020493 0.033643067026792955 0.5152535939117621 1.7779825659549818e-05 4.750072501828499 -0.5722073601847323 EDLVGPEVGAS(ph)PQSGRK ddPTM_PC-9_AZD4547_30min_R2 1 EDLVGPEVGASPQSGRK 17 1 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 EDLVGPEVGAS(0.996)PQS(0.004)GRK 128.99 4.5738e-05 4244900.0 13449.0 16324.0 21688.0 26903.0 25205.0 24707.0 24820.0 28034.0 23037.0 26330.0 True False 17725.502243421935 21600.41376678146 21400.40294931254 20700.928997206618 21705.72081996931 23162.067384243874 27028.931917288883 23701.989457232918 24254.688789032378 25408.194714228277 0.6976293452874034 0.8501357144703199 0.8422638125222088 0.8147343496865739 0.8542803242850768 0.911598310889573 1.0637879716087428 0.9328482296288486 0.9546010278113167 1.0 14.633006253195191 -6.7983678507263665 2.2287078083661624 0.9828283430706217 0.8094218401103073 0.7224600870430856 0.051764062483294966 0.1713558585597714 1.7471728283917392 0.020478028718893655 0.018435730676267293 1.5908606851416613e-07 6.7983678507263665 -0.17340650296031446 EDLVGPEVGAS(ph)PQSGRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EDLVGPEVGASPQSGRK 17 1 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 EDLVGPEVGAS(0.8)PQS(0.2)GRK;EDLVGPEVGAS(0.944)PQS(0.056)GRK 75.91199999999999 0.0039714 12828900.0 50026.0 65424.0 49380.0 72309.0 65013.0 42695.0 56485.0 45297.0 46258.0 41871.0 True False 58494.41374146183 71918.86234784688 50557.40647469284 68257.76115894117 52274.16934972545 40455.99903974809 51134.33188401385 44108.00174613871 46934.43573846184 49461.88084934637 1.182616041626626 1.454026032024564 1.0221488873155324 1.3800073912847004 1.0568576942907792 0.8179227790178687 1.0338129283793618 0.8917574703737047 0.9489011524130521 1.0 15.594029480588098 -6.479243735604681 5.58166600989065 0.9369562835464628 1.2544615023669183 0.6132144686760499 0.12029593305042813 0.12868066683799692 10.039268272999882 0.03579489734365322 0.0396811117156929 3.3170824334995926e-07 6.479243735604681 0.31750521882045557 EDLVGPEVGAS(ph)PQSGRK ddPTM_PC-9_Lapatinib_30min_R1 1 EDLVGPEVGASPQSGRK 17 1 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 EDLVGPEVGAS(0.786)PQS(0.214)GRK 91.166 0.0010370999999999998 21452000.0 26354.0 38517.0 30235.0 25976.0 19496.0 25990.0 27851.0 23405.0 24804.0 18712.0 True False 25978.187127268287 38427.81625297745 27749.195010475127 27886.361693395786 18349.283610610764 24878.468285649124 29292.988504010398 24492.481744153272 22010.312322300586 21946.344267827273 1.1837136431579443 1.7509894032470616 1.2644108135656411 1.2706609061207708 0.8360975015556601 1.133604211345589 1.3347548068382897 1.1160164738716218 1.0029147476086524 1.0 14.421693021090421 -5.724195972331639 2.4729720941352005 1.094762688430973 1.4662843351936368 0.3937442537671234 0.18305835280518498 0.2740505717915922 3.4089103474988804 0.05293852722821675 0.1002995663660695 1.8871395984612865e-06 5.724195972331639 0.37152164676266386 EDLVGPEVGASPQS(ph)GRK ddPTM_PC-9_Lapatinib_30min_R1 1 EDLVGPEVGASPQSGRK 17 1 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 EDLVGPEVGAS(0.094)PQS(0.906)GRK 106.39 0.00030242 24192000.0 28392.0 34924.0 45769.0 27696.0 32463.0 27119.0 27641.0 28581.0 30202.0 22858.0 True False 27987.124873544883 34843.135623724156 42006.04949344918 29732.85623114756 30553.59016471363 25959.18358747665 29072.115731548292 29908.977600070273 26800.33271884062 26808.974843629505 1.043946105242265 1.2996817605654836 1.5668651911705191 1.1090635283360284 1.1396776767081023 0.9683019861404814 1.0844172856709053 1.1156330211998915 0.999677640609561 1.0 14.710428432279501 -5.975262558383159 24.98922961847516 1.0609188700968921 1.3089242755709674 0.438891720604339 0.1275227894837378 212.04310459390342 214199.82687480573 0.036444288236181524 0.05405341450488929 1.058613533084931e-06 5.975262558383159 0.24800540547407524 EDNPEEPSKEITSHEEGGGDVS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 EDNPEEPSKEITSHEEGGGDVSPR 24 1 Q96JN0-3;A0A1P0AZG4 Q96JN0-3 LCOR Ligand-dependent corepressor 1 EDNPEEPSKEITS(0.001)HEEGGGDVS(0.999)PR;EDNPEEPS(0.001)KEIT(0.004)S(0.011)HEEGGGDVS(0.984)PR 55.998000000000005 0.0031125 9727300.0 36186.0 39571.0 43798.0 48122.0 52447.0 55645.0 44249.0 53660.0 45228.0 54047.0 True False 47692.39528444243 52361.55189691919 43217.209902895185 37028.2163774886 45165.639351118065 52165.50935347275 48187.07527832862 45368.07998413065 47618.65974520798 52154.83098062651 0.9144386893355727 1.0039636005410404 0.8286329202935908 0.7099671436236298 0.8659914815541314 1.0002047436957509 0.9239235248644223 0.8698730133165061 0.913024907757758 1.0 15.670513271968357 -6.570521360632187 23.990995144888938 0.9322819428721609 0.8612226048256342 0.19068705483248716 0.07789868982501852 165.45861018196385 83317.02224395258 0.028494435924558692 0.028494448353692248 2.688305616379501e-07 6.570521360632187 -0.07105933804652675 EDNPEEPSKEITSHEEGGGDVS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDNPEEPSKEITSHEEGGGDVSPR 24 1 Q96JN0-3;A0A1P0AZG4 Q96JN0-3 LCOR Ligand-dependent corepressor 1 EDNPEEPSKEIT(0.001)S(0.001)HEEGGGDVS(0.997)PR 49.653999999999996 0.013124 6367700.0 25326.0 21045.0 27524.0 24161.0 37459.0 25408.0 27859.0 27163.0 25647.0 25661.0 True False 29613.191588699152 23134.20851844032 28180.27654535127 22807.337501018876 30119.17785168147 24075.559751772304 25219.993838306473 26450.00003157747 26022.03885564294 30313.13616763576 0.9769095294176815 0.7631743673932319 0.9296390973705431 0.7523912199282582 0.9936015094287284 0.7942286017069032 0.8319823359363572 0.8725590082565321 0.8584409977158922 1.0 14.887655499221527 -10.793491011348095 2.470110009510961 1.0022012462630285 0.8604810369310726 0.21008514592501326 0.07909683256189354 1376261.0928642764 1461036.996021035 22645.824143995796 0.018713956502030973 1.608825675627831e-11 10.793491011348095 -0.14172020933195595 EDNPEEPSKEITSHEEGGGDVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 EDNPEEPSKEITSHEEGGGDVSPR 24 1 Q96JN0-3;A0A1P0AZG4 Q96JN0-3 LCOR Ligand-dependent corepressor 1 EDNPEEPSKEIT(0.001)S(0.002)HEEGGGDVS(0.997)PR;EDNPEEPS(0.001)KEIT(0.016)S(0.045)HEEGGGDVS(0.938)PR;EDNPEEPSKEIT(0.004)S(0.005)HEEGGGDVS(0.991)PR;EDNPEEPS(0.306)KEIT(0.034)S(0.034)HEEGGGDVS(0.626)PR 64.002 0.00071992 25430900.0 117575.2 92707.4 121748.3 98692.6 97872.8 103150.5 88445.3 88339.7 113940.9 74208.4 True False 115898.556087349 92492.74171122546 111738.62473602887 105950.78303286212 92116.11432932837 98738.99357055977 93024.56486782334 92444.2849619303 101107.67599113124 87035.22306352241 1.3316281846346365 1.0627047125934277 1.283832232548847 1.217332239793701 1.058377414188939 1.134471655211309 1.0688151485511748 1.0621479638704447 1.1616868715018756 1.0 16.409311755856358 -6.253950173297558 24.367437014310216 1.086096595431943 1.2166449450593158 0.45401034784921224 0.07651179322789432 400.67532190241815 1303664.6708013935 0.02147166415708385 0.027148867194541213 5.572496786440185e-07 6.253950173297558 0.13054834962737272 EDPDGEHARR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EDPDGEHARR 10 1 A0A087X0X3;P52272-2;P52272;M0R2T0;M0R019;M0QYQ7;M0R0N3 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 ; 70.55199999999999 0.02245 4821060.0 620.21 1944.52 4285.3 1475.16 3984.48 5502.8 1309.61 1855.27 4553.03 4355.3 False True 725.1993032941281 2137.559094715019 4387.47780409075 1392.511567733247 3203.7497468290053 5214.223480874238 1185.554260044673 1806.571128321054 4619.609450263495 5144.881413464173 0.14095549440581445 0.41547295708721665 0.8527850209741871 0.27065960433782577 0.6227062373964112 1.0134778747725062 0.23043373885004872 0.35113950801533556 0.8979039707647994 1.0 12.328922108879711 -14.522878745257291 0.07062627462876711 2.489514950093955 2.329710751994529e-13 0.2697650631763471 0.27447749093881213 499.4978612361733 2.527868218084978 122.62879679851203 14.922860548415967 3.0000000001592003e-15 14.522878745257291 -2.4895149500937217 EDPDGEHARR ddPTM_PC-9_Lapatinib_30min_R1 2 EDPDGEHARR 10 1 A0A087X0X3;P52272-2;P52272;M0R2T0;M0R019;M0QYQ7;M0R0N3 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 ; 79.97399999999999 0.011574 1092010.0 3194.79 3079.46 1229.95 1760.79 3498.3 2500.44 3080.88 3284.96 5144.0 3603.74 False True 3149.231708747266 3072.329699571457 1128.8282587442993 1890.28437042325 3292.536871922427 2393.502010010329 3240.3928915383826 3437.591233936071 4564.6285512785935 4226.6416573182905 0.745090775153478 0.7268961858291959 0.2670745121696727 0.44723080963116074 0.7789959828322583 0.566289315269029 0.766659005957543 0.8133150412654443 1.079965826621495 1.0 12.045296087798604 -7.764608741207139 1.133793893463827 1.0451066499976682 0.5706140822203198 0.582022820949712 0.14830108140084947 0.38096705541360887 0.8862931838157971 0.13618401156554522 0.053628897614877394 1.7194567596364403e-08 7.764608741207139 -0.4744925677773484 EDPGSGVRVS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EDPGSGVRVSPK 12 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 EDPGS(0.001)GVRVS(0.999)PK;EDPGS(0.007)GVRVS(0.993)PK 74.962 0.0095613 17350700.0 147964.0 112566.0 138803.0 196215.0 177617.0 178109.0 157797.0 159429.0 156002.0 148226.0 True False 173011.3827777884 123740.80855722293 142112.58993330912 185221.7096876129 142814.22388430263 168768.6504970253 142849.32580865227 155244.15767898897 158283.23412321176 175098.20044362967 0.9880820153459369 0.7066937766562569 0.8116165076125966 1.0578161809677897 0.815623595916279 0.9638514277670027 0.8158240658483554 0.8866119542386021 0.9039683658780305 1.0 17.417804731112952 -14.522878716674082 0.20876406879768997 1.5701669154755695 0.8625569900475978 0.11412441814544261 0.09693598534168386 323.68616226291545 3.215335666009107 77.26395264588598 0.2073420994691072 3.0000001976050177e-15 14.522878716674082 -0.7076099254279717 EDPGSGVRVS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 EDPGSGVRVSPK 12 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 EDPGS(0.009)GVRVS(0.991)PK;EDPGS(0.001)GVRVS(0.999)PK 63.408 0.022483000000000003 24838000.0 386380.0 269280.0 236660.0 266640.0 234230.0 235587.0 212735.0 188994.0 246180.0 168478.0 True False 380870.1503465855 268656.4987045145 217202.72833401882 286249.5950849648 220453.05191389812 225511.49319012 223749.3773796509 197775.35119651814 218452.61600967415 197599.19781717635 1.9274883428371807 1.359603184994112 1.0992085531388651 1.4486374350052271 1.115657625887058 1.1412571289827238 1.1323395026465104 1.0008914680893835 1.1055339213056519 1.0 17.592217564539915 -1.5874106195247943 0.8166766674550294 1.1107116359884401 199.9999972158769 0.8155011656780186 0.11521356675272895 203.7558016118467 0.7430455492383566 0.041550470169313236 74967.31096665683 0.02585766951544965 1.5874106195247943 198.88928557988845 EDPQARPLEGSSSEDSPPEGQAPPS(ph)HSPR ddPTM_PC-9_AZD4547_30min_R2 3 EDPQARPLEGSSSEDSPPEGQAPPSHSPR 29 1 Q12789;Q12789-3 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 1 EDPQARPLEGSSSEDSPPEGQAPPS(0.596)HS(0.404)PR;EDPQARPLEGSSSEDSPPEGQAPPS(0.774)HS(0.226)PR;EDPQARPLEGS(0.001)S(0.001)S(0.001)EDS(0.003)PPEGQAPPS(0.638)HS(0.355)PR 125.2 6.6902e-14 34687000.0 43429.0 43924.8 66246.6 70026.4 67072.8 59112.8 54989.6 71695.0 52375.8 65564.0 True False 57238.51862068342 58122.6326037198 65368.12679924055 53882.89537709511 57760.89948080288 55416.46727127257 59883.56787102939 60616.18513720184 55144.27786068504 63268.62431612841 0.9046904249835602 0.9186643969577067 1.0331839439501918 0.851652710320735 0.9129469797255968 0.8758917689497768 0.9464970752614246 0.9580765472997584 0.8715896458432666 1.0 15.949202606445732 -10.308203341150676 6.1375498864965925 1.0000000027675329 0.9210733500688075 0.1941695352242958 0.04922790502573565 1.8398987318416154e-09 3.4335181639913064e-10 0.047140372187039654 0.011433219292092548 4.918092116259419e-11 10.308203341150676 -0.07892665269872534 EDPQARPLEGSSSEDSPPEGQAPPS(ph)HSPR ddPTM_PC-9_Lapatinib_30min_R1 3 EDPQARPLEGSSSEDSPPEGQAPPSHSPR 29 1 Q12789;Q12789-3 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 1 EDPQARPLEGSSSEDSPPEGQAPPS(0.755)HS(0.245)PR;EDPQARPLEGSSSEDSPPEGQAPPS(0.793)HS(0.206)PR;EDPQARPLEGSSSEDSPPEGQAPPS(0.798)HS(0.202)PR 113.67 2.033e-13 28033300.0 46608.3 50724.3 59622.7 49338.9 47707.7 58389.7 50992.6 44918.1 53501.2 40652.2 True False 45943.65709508457 50606.85099984168 54720.75175627764 52967.447295745485 44901.62688294699 55892.508644038724 53632.747319291964 47005.158907586025 47475.3314633877 47678.87860434838 0.9636060754770865 1.0614102613400447 1.1476937662557993 1.1109205762845853 0.941750900971314 1.1722697823463752 1.1248743445572686 0.9858696404679931 0.9957308739861572 1.0 15.541062683911377 -7.779870532077209 24.933666323015036 0.9931001379310246 1.0769854778317847 0.2179847198803584 0.0700116977867032 384.74119967852687 520470.25217085856 0.039185249253643195 0.018877462913031447 1.660081722150335e-08 7.779870532077209 0.08388533990076008 EDPQARPLEGSSSEDSPPEGQAPPSHS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDPQARPLEGSSSEDSPPEGQAPPSHSPR 29 1 Q12789;Q12789-3 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 1 EDPQARPLEGSSSEDSPPEGQAPPS(0.131)HS(0.869)PR 114.18 2.394e-06 0.0 1754.5 1698.2 3970.7 3216.1 4125.0 2894.4 3765.0 1963.8 1726.9 3815.3 True False 2051.502197045434 1866.7860729871854 4065.376546963606 3035.912343736883 3316.735861560268 2742.6125687000067 3408.3519437605037 1912.252330818093 1752.152645526173 4506.98368810182 0.4551829647090321 0.41419854212372553 0.9020171423508739 0.6736018041848073 0.7359103318514911 0.608525070978257 0.7562379142303883 0.4242864991649138 0.38876391990318404 1.0 12.137946513251592 -5.204769799772574 24.99738351519531 0.6666642094223894 0.4346902735647686 0.2349535282144184 0.17876408374466576 446.931432505251 197142.91757362906 0.04570762991070525 0.12093101499853237 6.240655372698395e-06 5.204769799772574 -0.23197393585762077 EDPQARPLEGSSSEDSPPEGQAPPSHS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 EDPQARPLEGSSSEDSPPEGQAPPSHSPR 29 1 Q12789;Q12789-3 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 1 EDPQARPLEGSSSEDS(0.001)PPEGQAPPS(0.281)HS(0.718)PR 77.586 1.9118e-06 8316300.0 5875.7 6012.5 5143.0 5328.1 6540.4 7432.9 7257.1 5943.4 6363.9 5393.5 True False 5791.9114405285845 5998.5784256569 4720.1623925541135 5719.94624802056 6155.706530921145 7115.012193936182 7632.837128736986 6219.552061448426 5647.130567162102 6325.759288612996 0.9156073091422572 0.9482780093221292 0.7461811582130355 0.9042307787963162 0.973117415644006 1.1247680901712338 1.2066278181777896 0.9832103590543266 0.8927198000289872 1.0 12.627022943310383 -6.394262361538984 3.134974921255692 1.0503136977678276 0.8732034797553879 0.3991537917053306 0.09329139661869455 0.27332467811366884 5.087099470390909 0.03320918825003297 0.038049585653001684 4.0340162048273035e-07 6.394262361538984 -0.17711021801243965 EDQEAAELLS(ph)EPEEESER ddPTM_PC-9_Lapatinib_30min_R1 1 EDQEAAELLSEPEEESER 18 0 A0A0A0MTR7;A0A0A0MTC1;Q63HN8;Q63HN8-4 A0A0A0MTR7 RNF213 E3 ubiquitin-protein ligase RNF213 1 EDQEAAELLS(1)EPEEESER 166.47 1.2745999999999998e-07 7416900.0 18525.0 17922.0 19817.0 17465.0 18082.0 19959.0 21750.0 21201.0 22492.0 20021.0 True False 18260.83010293107 17880.502710124405 18187.722755832165 18749.434361532083 17018.452310579793 19105.400096701436 22876.10857643267 22186.07585805569 19958.714108739914 23481.60317369439 0.7776653905551063 0.7614685665992047 0.7745520023184459 0.7984733505136655 0.7247568313242326 0.8136326960036757 0.9742140861174234 0.9448279869966445 0.8499723788492838 1.0 14.519243289350996 -7.121017846215271 4.435605161341996 0.93682815184369 0.7691327769712836 0.8078268438830671 0.04034494613267745 0.09881948522226781 3.125664459005779 0.01547025023287839 0.011898205394936957 7.568017955577622e-08 7.121017846215271 -0.16769537487240638 EDQSILCTGESGAGK ddPTM_PC-9_Lapatinib_30min_R1 2 EDQSILCTGESGAGK 15 0 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580;Q5BKV1;A0A494C024;E7ERA5;Q7Z406;Q7Z406-6;Q7Z406-2;Q7Z406-4;Q7Z406-5;M0QY43;A0A2R8Y4C3;P35749-4;P35749-3;P35749;P35749-2 P35579;Q7Z406;P35749-4 MYH9;MYH10;MYH14;MYH11 Myosin-9;Myosin-10;Myosin-14;Myosin-11 0 ; 112.02 0.0016664000000000002 12798800.0 46728.0 55222.0 49651.0 49722.0 47378.0 47084.0 61221.0 50346.0 54219.0 52639.0 False True 46061.650151134294 55094.13685182957 45568.886438402544 53378.72174772959 44591.31918873185 45070.32707816478 64390.723823346365 52685.258957109174 48112.2852686186 61737.58101294137 0.7460877053391336 0.8923922179633308 0.7381061209516848 0.8646066281174897 0.7222718878374043 0.7300306610444809 1.0429745183869261 0.853374202433771 0.7793030513866968 1.0 15.913861336279584 -7.233596715661609 24.99165811755174 0.9066941884869648 0.7862664790818857 0.37062221282876917 0.0865686013552471 891.1897172135916 799935.6407898146 0.032855025430824726 0.0254437135586283 5.839871409866594e-08 7.233596715661609 -0.12042770940507908 EDQTEYLEER ddPTM_PC-9_AZD4547_30min_R2 1 EDQTEYLEER 10 0 P07900;P07900-2;G3V2J8;Q58FF6;P08238;Q58FF7 P07900;P08238 HSP90AA1;HSP90AB4P;HSP90AB1;HSP90AB3P Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-beta 4;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 187.16 0.006733499999999999 161030000.0 52470.0 64561.0 71888.0 68435.0 56319.0 57942.0 80486.0 83886.0 70765.0 64087.0 False True 69154.36855620099 85429.08069083432 70934.71814921523 52658.36806021019 48500.07898670311 54318.87758035611 87649.09807795785 70923.3462085127 74505.49343038922 61843.333636564676 1.118218642005962 1.381378972758426 1.147006701903846 0.8514801024418919 0.7842410189548319 0.8783303613542631 1.4172764132193483 1.146822818855604 1.204745751065691 1.0 15.916330468723478 -5.522766357836227 24.999959468145892 1.0413017937479652 1.2533973397452884 0.17181313046694302 0.1855360206246308 6.977144523469283 1551960.2079324347 0.05589155539528252 0.0981482513513109 3.000776445420927e-06 5.522766357836227 0.21209554599732328 EDQTEYLEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EDQTEYLEER 10 0 P07900;P07900-2;G3V2J8;Q58FF6;P08238;Q58FF7 P07900;P08238 HSP90AA1;HSP90AB4P;HSP90AB1;HSP90AB3P Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-beta 4;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 ; 187.16 0.00071751 276780000.0 162391.0 235896.0 223456.0 158640.0 239224.0 142734.0 203285.0 118986.0 137000.0 126899.0 False True 189880.58893155007 259314.19589764753 228784.03850159896 149751.915117819 192349.77448385255 135248.77777115357 184028.37314405153 115862.74357608822 139003.36582146396 149904.78416806876 1.266674642742967 1.7298593726462541 1.5261957099720924 0.9989802256739294 1.2831463355311978 0.902231229788615 1.2276350896027737 0.7729089116074266 0.9272777156039099 1.0 17.193686901654587 -5.759627191458251 24.92644134398677 1.0217691347268791 1.5298049891811987 0.6229231398941351 0.17496107944207628 28.385137119797662 390420.5794044595 0.04769552779631922 0.07748478305282423 1.7392932380971778e-06 5.759627191458251 0.5080358544543195 EDQTEYLEER ddPTM_PC-9_Lapatinib_30min_R1 4 EDQTEYLEER 10 0 P07900;P07900-2;G3V2J8;Q58FF6;P08238;Q58FF7 P07900;P08238 HSP90AA1;HSP90AB4P;HSP90AB1;HSP90AB3P Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-beta 4;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 ;;; 145.46 0.00063573 375270000.0 57675.0 102148.0 97257.0 83564.0 98633.0 112688.0 103312.0 103372.0 104128.0 92578.0 False True 56852.54392370039 101911.48258195429 89260.90488287658 89709.57532133223 92831.60085993905 107868.5969285582 108660.98985050173 108175.04049803954 92400.00812354924 108579.98394756923 0.5236005924549885 0.9385844322022096 0.8220751342713277 0.8262072995392127 0.8549605321802708 0.9934482674140517 1.0007460482124553 0.9962705515804346 0.8509856491429127 1.0 16.72839865012908 -4.7595297895010855 24.99976755257453 0.9169856940846528 0.5236000965385145 0.7315304267086165 0.07208201274271167 28.498536460479958 372994.140363616 0.019629807663376797 0.12380796615082783 1.7396833640862078e-05 4.7595297895010855 -0.39338559754613833 EDQTEYLEERR ddPTM_PC-9_AZD4547_30min_R2 4 EDQTEYLEERR 11 1 P07900;P07900-2;G3V2J8;P08238;Q58FF7 P07900;P08238 HSP90AA1;HSP90AB1;HSP90AB3P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 ;;; 176.32 8.7081e-05 62270000.0 138190.0 104054.0 167045.0 283623.0 214597.0 159289.0 140808.0 164126.0 153505.0 179878.0 False True 182131.5454694382 137687.4206131265 164829.8741547359 218238.09928166843 184803.91076385442 149328.63364912095 153339.63921875998 138764.09794027978 161618.9609133314 173580.52597060223 1.0492625509170548 0.793219284497648 0.9495873643259478 1.2572729461519747 1.0646580872508302 0.8602844864890626 0.8833919494213869 0.7994220386437878 0.9310892452342455 1.0 17.405245575090312 -6.767676610736447 24.940588450479357 0.8815860534514759 1.01900446381916 0.22309141405534305 0.11800413004102664 235.8833439092555 943212.0332009437 0.044603528757535725 0.04030953236655056 1.7073532644541698e-07 6.767676610736447 0.1374184103676841 EDQTEYLEERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EDQTEYLEERR 11 1 P07900;P07900-2;G3V2J8;P08238;Q58FF7 P07900;P08238 HSP90AA1;HSP90AB1;HSP90AB3P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 ;;; 160.56 0.00013241 34155100.0 106477.0 78702.0 94544.0 138831.0 158129.0 165694.0 131590.0 168276.0 149027.0 106878.0 False True 124501.45308338907 86515.01443660184 96798.28752011646 131052.7491661748 127144.75758852444 157004.71495238348 119124.84257090154 163858.93330316033 151206.237943615 126254.13535421743 0.9861178228664665 0.6852449956896549 0.7666939957930097 1.038007577324057 1.0070542024766815 1.2435609694042298 0.9435322038100851 1.2978500295728075 1.1976339429943597 1.0 16.945971117408682 -6.005098996389189 1.9726390384825054 1.1335885193289201 0.7994873354382864 0.5166120400996063 0.12871314793998706 0.24584477190163245 1.9202524410868875 0.040718287381875135 0.06473534939873195 9.883277820223603e-07 6.005098996389189 -0.3341011838906337 EDQTEYLEERR ddPTM_PC-9_Lapatinib_30min_R1 4 EDQTEYLEERR 11 1 P07900;P07900-2;G3V2J8;P08238;Q58FF7 P07900;P08238 HSP90AA1;HSP90AB1;HSP90AB3P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 ;;; 142.89 6.4505e-05 35092500.0 196220.0 120968.0 153513.0 113710.0 122769.0 126932.0 80400.0 81693.0 144445.0 88909.0 False True 193421.8668176589 120687.90602825205 140891.7537173166 122072.61272544006 115547.96879314064 121503.41425294393 84562.71859977857 85488.755014959 128176.08302671787 104276.80218620446 1.8548887457468284 1.1573801986442076 1.351132282189952 1.1706593428848928 1.108088916907996 1.1652008088623427 0.8109446859405706 0.8198252461012746 1.2291907724388889 1.0 16.67005872056596 -1.5228787452803731 0.519333539276262 0.9934818106652408 28.459573288360183 0.6844916549380291 0.1578507540345344 69.65048649880072 0.7005275317059272 0.0842367287859369 2106.4611878478763 0.029999999999997543 1.5228787452803731 27.466091477694942 EDS(ph)FESLDSLGSR ddPTM_PC-9_AZD4547_30min_R2 1 EDSFESLDSLGSR 13 0 E9PMS6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 EDS(0.989)FES(0.011)LDSLGSR 101.45 0.0019986 2478200.0 4051.0 4075.9 5917.8 8038.9 8303.2 7286.8 6886.8 8955.3 7035.4 6603.1 True False 5339.133733965513 5393.354966431303 5839.326105378167 6185.655804766912 7150.444003664714 6831.155244080964 7499.711858500609 7571.464157321755 7407.276880946237 6371.927478827216 0.8379150189179815 0.8464244115069521 0.9164144012594637 0.970766824531627 1.1221791251429603 1.072070463259301 1.176992657782252 1.1882533475907229 1.1624860618014412 1.0 12.6375141317934 -5.974184399946846 1.175094380325921 1.1417216661025167 0.8333650360830273 0.8203006879534043 0.054016974684264966 0.18267994140628374 0.5119662871597335 0.019914088439022367 0.04028331179252878 1.0612448605969615e-06 5.974184399946846 -0.30835663001948943 EDS(ph)FESLDSLGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EDSFESLDSLGSR 13 0 E9PMS6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 EDS(1)FESLDSLGSR;EDS(0.982)FES(0.009)LDS(0.009)LGSR 120.29 0.0002149 4194700.0 11688.0 9802.5 11996.3 12700.0 13681.5 12475.0 10803.7 13044.6 10934.6 8536.8 True False 13666.54755147735 10775.62741753439 12282.337288221093 11988.460173955536 11000.70828846952 11820.789039017618 9780.295323985487 12702.19307189617 11094.49783876918 10084.45426272838 1.3552094337904035 1.0685384788109504 1.217947641809034 1.188806043601612 1.0908580674640536 1.1721793496259525 0.9698388300627184 1.2595816036216076 1.1001584765745698 1.0 13.299845391734442 -1.5228787452803376 0.1319078034101273 1.0103182773736719 1.7664250832934238 0.2991116462051585 0.09461316401437132 121.4873787269955 1.0853270455556023 0.4739465746031601 17.119062979694036 0.029999999999999995 1.5228787452803376 0.756106805919752 EDS(ph)FESLDSLGSR ddPTM_PC-9_Lapatinib_30min_R1 1 EDSFESLDSLGSR 13 0 E9PMS6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 EDS(0.999)FESLDSLGSR 96.37100000000001 0.0032804 2430000.0 12724.0 9512.5 8994.7 8796.0 9486.1 10200.0 8096.3 8014.3 9261.4 8022.5 True False 12542.553426704178 9490.474390696263 8255.190486546071 9442.887182595834 8928.146248390165 9763.76977736133 8515.486798499855 8386.673635640565 8218.283605134442 9409.178435690694 1.3330126017302462 1.0086400694344577 0.8773550786573098 1.0035825388088377 0.9488762817510307 1.0376856857476109 0.9050191636497288 0.8913290031601925 0.8734326446569474 1.0 13.199853043907163 -4.7732591539681675 3.558159283831782 0.9425468679021459 1.3824659546450149 0.8226401951287328 0.0541694203485501 0.11591870388606804 2.435507888568826 0.014043826282319117 0.1393234064049252 1.6855469188273134e-05 4.7732591539681675 0.43991908674286895 EDS(ph)FVWYMDNPQNLPSGS(ph)SRVGAIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EDSFVWYMDNPQNLPSGSSRVGAIK 25 1 Q9HB21;R4GMZ9;Q5RGS4;Q9HB21-2 Q9HB21 PLEKHA1 Pleckstrin homology domain-containing family A member 1 2 EDS(0.964)FVWY(0.036)MDNPQNLPS(0.209)GS(0.42)S(0.371)RVGAIK;EDS(0.931)FVWY(0.069)MDNPQNLPS(0.024)GS(0.519)S(0.457)RVGAIK 60.562 0.0053198 8880100.0 4061.7000000000003 7194.5 97325.0 20847.4 65141.0 43046.0 20277.1 26605.0 37568.0 18200.9 True False 4749.265587768274 7908.722413205933 99645.59710711801 19679.38776618273 52377.08866858118 40788.591981847865 18356.30629450894 25906.646940327628 38117.36092832664 21500.579091754866 0.22089012428458463 0.36783764657942647 4.634554105816179 0.915295708185342 2.436078044459136 1.8970927158650182 0.8537586925529971 1.2049278686759846 1.7728527573912671 1.0 14.392087897110786 -7.241757779418682 23.273385686620227 1.2249621069794194 1.807682356773455 0.04475581388760497 1.194591201102436 1213.1441162851845 1434536.7947619734 0.4664878518882123 0.36064891225065326 5.7311558762627684e-08 7.241757779418682 0.5827202497940356 EDS(ph)GTFSLGK ddPTM_PC-9_AZD4547_30min_R2 4 EDSGTFSLGK 10 0 G5E9Q4;O75569 G5E9Q4 PRKRA Interferon-inducible double-stranded RNA-dependent protein kinase activator A 1 EDS(0.919)GT(0.077)FS(0.003)LGK;EDS(0.981)GT(0.013)FS(0.006)LGK;EDS(0.987)GT(0.013)FSLGK;EDS(1)GTFSLGK 171.67 0.00018187 289839000.0 598727.0 709926.0 637909.0 513013.0 612273.0 753592.0 689370.0 806236.0 712755.0 543448.0 True False 789109.7317047563 939395.6961404129 629449.9098576643 394745.77882183937 527269.4625512823 706469.7731099331 750722.5945133528 681650.7516601859 750429.7741818279 524422.0509326985 1.5047226376185052 1.791297094524673 1.2002735368167126 0.7527253633209616 1.0054296184028104 1.3471397166718255 1.4315236996197487 1.2998132905507156 1.4309653319252473 1.0 19.000368823807328 -5.274699434986949 23.148727365051414 1.1871514825598832 1.64800982535797 0.43110636422367943 0.2134153560738979 260.73998760985575 455188.2756191212 0.06189962867684717 0.13034794300570104 5.312519840570637e-06 5.274699434986949 0.4608583427980868 EDS(ph)GTFSLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EDSGTFSLGK 10 0 G5E9Q4;O75569 G5E9Q4 PRKRA Interferon-inducible double-stranded RNA-dependent protein kinase activator A 1 EDS(0.995)GT(0.005)FSLGK;EDS(0.957)GT(0.024)FS(0.019)LGK;EDS(0.997)GT(0.003)FSLGK;EDS(0.963)GT(0.023)FS(0.014)LGK 141.71 0.00011139 168845000.0 600313.0 830094.0 577471.0 583718.0 725424.0 521179.0 628743.0 410696.0 447671.0 466902.0 True False 701934.1341777922 912500.2464198725 591240.0987109621 551014.1728992885 583282.3746997572 493847.4557568071 569183.9113348781 399915.6651683814 454217.34146467486 551547.6366058022 1.2726627540233175 1.65443596501538 1.0719656099868824 0.9990327876123327 1.0575376195776107 0.8953849549531583 1.0319759773382562 0.7250791021958561 0.823532386540366 1.0 19.07312596973128 -5.435085919060565 4.270215811026606 0.934655702400948 1.4600200789932547 0.7230416034518432 0.12907534483709135 0.11163588360506269 3.597173907427743 0.03513306588229943 0.07605810111660234 3.6720964604302773e-06 5.435085919060565 0.5253643765923067 EDS(ph)GTFSLGK ddPTM_PC-9_Lapatinib_30min_R1 4 EDSGTFSLGK 10 0 G5E9Q4;O75569 G5E9Q4 PRKRA Interferon-inducible double-stranded RNA-dependent protein kinase activator A 1 EDS(0.996)GT(0.002)FS(0.003)LGK;EDS(0.893)GT(0.083)FS(0.024)LGK;EDS(0.653)GT(0.025)FS(0.322)LGK;EDS(0.982)GT(0.018)FSLGK 150.09 0.00011719 332161000.0 776405.0 761209.0 614251.0 590600.0 859413.0 834334.0 957233.0 905555.0 801308.0 903528.0 True False 765333.3223247606 759446.4673290408 563749.6538574274 634034.6941838443 808864.0170109665 798651.4797475472 1006793.84096296 947630.3911910559 711056.254892681 1059701.6109246174 0.7222158713687217 0.7166606707961912 0.5319890505455975 0.59831436288054 0.7632941279623153 0.7536569459875624 0.9500729550505317 0.8942426636156791 0.6709966726126478 1.0 20.015226659545498 -6.722312749313328 1.9181979195950736 0.8656709854260414 0.6434751451758998 0.5082750392966193 0.09945583898813605 0.2897959282269927 2.197918850736998 0.04056492791748368 0.038230993420725286 1.8953405344479218e-07 6.722312749313328 -0.2221958402501416 EDS(ph)LPEESSAPDFANLK ddPTM_PC-9_Lapatinib_30min_R1 2 EDSLPEESSAPDFANLK 17 0 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 EDS(1)LPEESSAPDFANLK;EDS(0.855)LPEES(0.073)S(0.073)APDFANLK 157.58 3.1403000000000005e-17 0.0 9711.400000000001 10257.2 13148.3 14480.5 14397.0 14695.599999999999 15650.8 15853.2 16878.8 28795.0 True False 9572.913655147357 10233.450083600485 12067.29752790574 15545.444275531927 13550.196765591045 14067.10344511677 16461.121844047473 16589.79754695196 14977.731802356358 33772.177383074275 0.2834556252196238 0.3030142228475094 0.35731476211994406 0.46030328750206356 0.40122366443515267 0.4165293604127175 0.4874166583140521 0.49122676808118176 0.443493223207539 1.0 15.043547576321465 -14.522878745279513 0.17549290087146313 3.3813706932947136 0.27760163473478855 0.9442362607296548 0.04512175972874582 29.574788897900927 0.281399977208621 24.49388969358343 0.15996431902216496 3.0000000000056946e-15 14.522878745279513 -3.103769058559925 EDS(ph)RGSLIPEGATGFPDQGNTGENTR ddPTM_PC-9_AZD4547_30min_R2 1 EDSRGSLIPEGATGFPDQGNTGENTR 26 1 A0A0J9YW64;A6NIW2;Q5JSL3 A0A0J9YW64 DOCK11 Dedicator of cytokinesis protein 11 1 EDS(0.797)RGS(0.203)LIPEGATGFPDQGNTGENTR 111.33 1.3193e-10 5220700.0 5095.6 6014.5 12177.0 14921.0 10536.0 10793.0 9626.4 10578.0 9977.6 9656.2 True False 6715.89480493574 7958.56950504209 12015.525023689548 11481.193977151981 9073.25826459816 10118.112003810424 10483.130951192168 8943.413158258183 10504.995566325882 9318.139377118536 0.720733456877365 0.8540942760080428 1.2894768512686843 1.2321337460722046 0.9737199560331001 1.0858511119351022 1.1250240554390467 0.9597852957876415 1.1273705126284943 1.0 13.185826194543303 -5.059832764382964 5.900970186951236 1.0981014932018514 0.7498076160449338 0.6162852220628211 0.10082678206201834 0.12238545087582674 8.90146751652272 0.026823286392276508 0.07657368575780191 8.71299040179984e-06 5.059832764382964 -0.3482938771569175 EDS(ph)RGSLIPEGATGFPDQGNTGENTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDSRGSLIPEGATGFPDQGNTGENTR 26 1 A0A0J9YW64;A6NIW2;Q5JSL3 A0A0J9YW64 DOCK11 Dedicator of cytokinesis protein 11 1 EDS(0.732)RGS(0.268)LIPEGATGFPDQGNTGENTR 103.43 5.9871e-10 5390200.0 8411.6 5622.4 7616.4 9498.3 8777.0 8359.7 9020.7 8222.4 7611.2 7370.3 True False 9835.517743327087 6180.554714852878 7798.003861357846 8966.14104490408 7057.209856221684 7921.302615589226 8166.193991787619 8006.57071235293 7722.499401024266 8706.4770467373 1.1296782487944292 0.7098800906124255 0.8956554780420746 1.029824232783579 0.810570086883343 0.90981720540545 0.9379446988662138 0.9196108448196443 0.886983260803315 1.0 13.087873355340042 -10.976050115871619 2.6339877643850476 1.0033024507215835 0.9089175003921899 0.05236658330577826 0.10689086913635774 22053737.527307432 22604975.89692561 536002.9712588334 0.025710034549828276 1.0566955636742588e-11 10.976050115871619 -0.09438495032939365 EDS(ph)RGSLIPEGATGFPDQGNTGENTR ddPTM_PC-9_Lapatinib_30min_R1 1 EDSRGSLIPEGATGFPDQGNTGENTR 26 1 A0A0J9YW64;A6NIW2;Q5JSL3 A0A0J9YW64 DOCK11 Dedicator of cytokinesis protein 11 1 EDS(0.497)RGS(0.497)LIPEGAT(0.006)GFPDQGNTGENTR 95.54299999999999 2.1176000000000002e-09 4184500.0 16649.0 8959.6 9455.3 10874.0 11205.0 13471.0 6087.4 7974.2 13139.0 8846.2 True False 16411.582206947332 8938.854596676189 8677.921732513496 11673.710234600618 10545.943929877589 12894.87673243475 6402.575786123044 8344.710443248317 11659.14746019623 10375.25388317943 1.581800541146672 0.8615552638348484 0.8364057236789469 1.1251493569257396 1.0164516501109322 1.2428492717021782 0.6171006375567376 0.8042897588055102 1.1237457503664825 1.0 13.340859019288288 -7.245136054436206 24.989051394186646 0.8699748172262257 1.0832816904741738 0.17597869531249344 0.23235286530096524 1531.3461668538862 2347186.4790248866 0.08889560336469125 0.06864305822232172 5.6867475026303144e-08 7.245136054436206 0.21330687324794806 EDS(ph)VPNMAT(ph)EKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDSVPNMATEKK 12 1 A6QL64 A6QL64 ANKRD36 Ankyrin repeat domain-containing protein 36A 2 EDS(1)VPNMAT(1)EKK 81.494 0.020814 0.0 2177.2 1294.0 1048.3 3159.7 2112.3 946.05 1985.5 3183.2 1275.0 1016.8 True False 2545.7569583398795 1422.459768251925 1073.2954476998882 2982.672252885615 1698.4099782724236 896.4374725741571 1797.41906622483 3099.6443728791924 1293.6444629369803 1201.137791015629 2.1194545516608048 1.1842602729609863 0.8935656306279041 2.483205736423961 1.41400095057897 0.7463235935788592 1.496430367664156 2.58059016714333 1.0770158699637047 1.0 10.230185946956395 EDS(ph)YHVR ddPTM_PC-9_Lapatinib_30min_R1 1 EDSYHVR 7 0 B1AVT0;P49760-2;P49760-3;P49760 B1AVT0 CLK2 Dual specificity protein kinase CLK2 1 EDS(0.999)Y(0.001)HVR 70.816 0.043012 2478500.0 16094.0 23512.0 27081.0 24555.0 27843.0 28111.0 21291.0 25261.0 28725.0 25261.0 True False 15864.49660872186 23457.55940857297 24854.50471568305 26360.856613078744 26205.32948144416 26908.758059941585 22393.34380233691 26434.718279814384 25489.68801234013 29627.33019183329 0.5354683161122251 0.7917540749263664 0.838904638209154 0.8897479604944308 0.8844985124129613 0.9082410695027433 0.7558340106024668 0.8922409852204994 0.8603437382746795 1.0 14.854641006100348 -4.4575104826872245 1.4799612831801174 0.874700435223776 0.1075473681834454 0.7664138749759448 0.057149454633302316 1.2257958894108862 1.3393892400219398 0.015514252001612423 1.743840527567824 3.487301666361855e-05 4.4575104826872245 -0.7671530670403306 EDSAPPS(ph)SVAR ddPTM_PC-9_AZD4547_30min_R2 1 EDSAPPSSVAR 11 0 Q9BZE4-3;Q9BZE4-2;Q9BZE4 Q9BZE4-3 GTPBP4 Nucleolar GTP-binding protein 1 1 EDS(0.026)APPS(0.487)S(0.487)VAR 78.548 0.018268 2880700.0 21539.0 27202.0 37805.0 42601.0 31459.0 39330.0 31160.0 43854.0 35241.0 40199.0 True False 28387.953960968458 35994.514535897404 37303.680998651806 32779.99762888891 27091.460871867283 36870.68888259649 33933.17963508144 37077.37196466766 37103.767314072575 38791.645245623324 0.7318058767866087 0.9278934757209993 0.9616421464583434 0.8450272583524236 0.6983839097395304 0.9504801523404434 0.8747548452823088 0.9558081831770444 0.9564886222055461 1.0 15.243458344832703 -7.74132091346779 1.2347478646459864 0.9864667425531358 0.8515784514064372 0.3128081317771547 0.08082965337956749 0.6605464294259962 1.8376612548792806 0.07031219688524061 0.027750876034117692 1.8141746182853108e-08 7.74132091346779 -0.13488829114669865 EDSAPPS(ph)SVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDSAPPSSVAR 11 0 Q9BZE4-3;Q9BZE4-2;Q9BZE4 Q9BZE4-3 GTPBP4 Nucleolar GTP-binding protein 1 1 EDSAPPS(0.5)S(0.5)VAR 96.06700000000001 0.014685 0.0 21260.0 23213.0 24855.0 24247.0 28284.0 19910.0 22388.0 23463.0 23523.0 16800.0 True False 24858.89809585974 25517.43323062747 25447.6374631124 22888.519199834645 22741.953238392867 18865.88455044816 20267.246564916386 22847.12111110343 23866.97937385615 19845.707011273174 1.2526083390094829 1.285791089031624 1.2822741688495705 1.1533234460648356 1.1459381732016152 0.950627989203487 1.0212408433422786 1.1512374488913562 1.202626812957519 1.0 14.276539339392283 -6.019649382363109 1.9739942335641247 1.0744036528495715 1.2769663593697196 0.5974681869398051 0.07172297156347572 0.24943574540956662 1.9465811086537623 0.025155111293267352 0.03950920236887223 9.557638885722668e-07 6.019649382363109 0.20256270652014807 EDSAPPS(ph)SVAR ddPTM_PC-9_Lapatinib_30min_R1 1 EDSAPPSSVAR 11 0 Q9BZE4-3;Q9BZE4-2;Q9BZE4 Q9BZE4-3 GTPBP4 Nucleolar GTP-binding protein 1 1 EDS(0.002)APPS(0.499)S(0.499)VAR 88.803 0.0096288 3253400.0 18369.0 24169.0 25499.0 22105.0 29818.0 22794.0 26676.0 24743.0 25908.0 23122.0 True False 18107.054691537953 24113.03816543893 23402.570648986446 23730.67544011834 28064.163864443566 21819.153755409236 28057.15275332955 25892.650108762406 22989.96821666519 27118.606891871634 0.6676985570731973 0.889169501279449 0.8629709756956944 0.8750698564545817 1.0348674611620756 0.8045823977023383 1.0346089260853304 0.9547927816499789 0.8477562401465417 1.0 14.726995447337469 -4.084740039482823 1.0024875178569388 0.9351657706924162 8.994358636519703e-16 0.5145351073562501 0.07540972885813058 5.35060578910241 1.5930495497135444 0.023091891947846305 7.539619456051952 8.227349762826678e-05 4.084740039482823 -0.9351657706924154 EDSAPPSS(ph)VAR ddPTM_PC-9_AZD4547_30min_R2 1 EDSAPPSSVAR 11 0 Q9BZE4-3;Q9BZE4-2;Q9BZE4 Q9BZE4-3 GTPBP4 Nucleolar GTP-binding protein 1 1 EDS(0.001)APPS(0.146)S(0.854)VAR 114.76 0.0023298000000000004 0.0 24161.0 27634.0 30155.0 35654.0 32575.0 29910.0 28055.0 44869.0 30568.0 37008.0 True False 31843.69541998046 36566.15008767698 29755.124997073024 27434.521148808864 28052.5235354295 28039.722971738127 30551.84065026348 37935.5270370473 32183.762074191145 35712.36118435853 0.8916715211182259 1.0239073775858987 0.8331883978062283 0.7682079884660431 0.7855129878031161 0.7851545527048236 0.855497638269987 1.0622519984386383 0.9011939005670435 1.0 15.124135902897956 -7.688810181422438 8.961464395436591 0.9860036447824027 0.8467663484113507 0.4003693155088244 0.07781705646573255 0.3243200588551382 36.54725932580774 0.04052442855487678 0.02330051000075807 2.0473392787932464e-08 7.688810181422438 -0.13923729637105198 EDSAPPSS(ph)VAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDSAPPSSVAR 11 0 Q9BZE4-3;Q9BZE4-2;Q9BZE4 Q9BZE4-3 GTPBP4 Nucleolar GTP-binding protein 1 1 EDSAPPS(0.147)S(0.853)VAR 132.03 0.00067196 0.0 19405.0 26693.0 27021.0 29630.0 29537.0 20301.0 21070.0 27554.0 25921.0 17959.0 True False 22689.883233779783 29342.904632108693 27665.283117713145 27969.927161756117 23749.436883128623 19236.379822132 19074.097066410057 26830.736695876218 26300.045587285844 21214.82453663423 1.0695296204122917 1.3831320914975618 1.3040542979716905 1.318414258550997 1.119473641750728 0.9067423484419675 0.8990928505429061 1.264716408544615 1.2397013014116776 1.0 14.37278512599924 -6.381229413726943 4.799918771843669 1.0634618116164871 1.2785589133685449 0.33953086392189624 0.1359133191842227 0.27922957007828203 9.795331125730796 0.04614630964273887 0.05245430383942254 4.156909659665175e-07 6.381229413726943 0.21509710175205776 EDSGLFS(ph)PIR ddPTM_PC-9_AZD4547_30min_R2 6 EDSGLFSPIR 10 0 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 EDS(0.002)GLFS(0.998)PIR;EDSGLFS(1)PIR;EDSGLFS(1)PIR;EDS(0.004)GLFS(0.996)PIR;EDSGLFS(1)PIR;EDS(0.001)GLFS(0.999)PIR 152.67 0.00011643 145366500.0 150839.5 146726.6 201241.1 265831.0 232342.3 197475.2 187349.5 227587.4 189313.7 195575.9 True False 198803.32334349284 194153.1040549519 198572.51152540103 204547.76999800873 200085.58216502916 185127.04452653244 204023.242555927 192418.99676817597 199320.43569042158 188728.84726967124 1.053380689913431 1.0287410052239128 1.0521577087876999 1.083818255434656 1.060174875540518 0.9809154626055007 1.0810389906340172 1.019552652135007 1.0561206650386425 1.0 17.52595543066657 EDSGLFS(ph)PIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EDSGLFSPIR 10 0 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 EDSGLFS(1)PIR;EDS(0.001)GLFS(0.999)PIR;EDSGLFS(1)PIR;EDS(0.001)GLFS(0.999)PIR 122.18 0.0005605 57109300.0 51434.1 55180.9 55477.6 61107.9 82334.0 90650.4 102481.0 93814.0 88495.0 71513.0 True False 60140.87726021919 60658.89507413653 56800.39638396961 57684.22247748481 66201.2437395645 85896.5334430911 92773.2577818114 91351.48190414961 89789.07195890817 84477.74080340355 0.7119138922071666 0.7180458958449399 0.6723711577012387 0.682833394085756 0.7836531032905806 1.0167948695856979 1.0981976660303117 1.0813674825507305 1.062872552047351 1.0 16.36628363262522 -6.719632070726747 2.7328468799478483 1.068041067230737 0.6976002946167102 0.9749330690600988 0.02744034488903192 0.037145097901071865 0.5673022755800552 0.010133976796456005 0.009637673362670313 1.9070756862889106e-07 6.719632070726747 -0.37044077261402675 EDSGLFS(ph)PIR ddPTM_PC-9_Lapatinib_30min_R1 6 EDSGLFSPIR 10 0 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 EDS(0.001)GLFS(0.999)PIR;EDSGLFS(1)PIR;EDSGLFS(1)PIR;EDS(0.001)GLFS(0.999)PIR;EDSGLFS(1)PIR;EDS(0.001)GLFS(0.999)PIR 152.96 0.00013692 93640010.0 132147.9 135736.3 141355.1 110998.7 193941.0 222274.3 237766.4 206900.8 252914.0 202789.4 True False 130263.44671304336 135422.01093696372 129733.42932446528 119161.91467880874 182533.77168267642 212768.14633570032 250076.78079206983 216514.16649650532 224428.16201751027 237841.27759010944 0.5476906617426458 0.5693797658215876 0.5454622117698388 0.5010144407488839 0.7674604405600748 0.8945804045939426 1.0514439853583648 0.9103304888466046 0.9436047615094171 1.0 17.859639592408044 -6.557873828283992 2.206608771737242 0.9668304460673338 0.5420372422840035 0.9525202737501158 0.044111015984935276 0.06090555913943677 0.599602590358165 0.01623876134241418 0.017089616972714727 2.767745617156112e-07 6.557873828283992 -0.4247932037833303 EDSGSS(ph)SPPGVFLEK ddPTM_PC-9_Lapatinib_30min_R1 1 EDSGSSSPPGVFLEK 15 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 EDS(0.098)GS(0.068)S(0.457)S(0.377)PPGVFLEK 72.175 0.020176 4676700.0 15136.0 21968.0 20603.0 20175.0 19093.0 22431.0 20227.0 22239.0 22864.0 18537.0 True False 14920.157864397539 21917.13444570989 18909.10086987991 21658.736801827057 17969.987278282275 21471.678419214895 21274.2550885289 23272.305127460986 20288.81555140625 21741.095751000117 0.6862652202666093 1.008097047946706 0.8697400115635877 0.9962118308057555 0.8265446914034051 0.9876079230379716 0.9785272707586625 1.0704292641915452 0.9332011497384136 1.0 14.408137033562152 -4.755366538608029 24.997134125973684 0.9606293352568084 0.6862647707117853 0.6045322105223745 0.06720523632018885 139.58207066190084 574494.2440721914 0.016614901662494002 0.1483887450810838 1.7564405763705557e-05 4.755366538608029 -0.2743645645450231 EDSGSSS(ph)PPGVFLEK ddPTM_PC-9_AZD4547_30min_R2 2 EDSGSSSPPGVFLEK 15 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 EDS(0.006)GS(0.01)S(0.044)S(0.94)PPGVFLEK;EDSGS(0.001)S(0.2)S(0.799)PPGVFLEK 121.95 5.7676e-05 5719700.0 69849.0 80965.0 79848.0 84443.0 75355.0 88472.0 80396.0 103753.0 85321.0 74343.0 True False 92059.52905054484 107135.3528931303 78789.16334824357 64975.97098134479 64893.258971981275 82939.83185408295 87551.08825231115 87720.35785675551 89830.89387372615 71740.27419824811 1.283233582243444 1.4933780793347808 1.098255676170354 0.9057112160149996 0.9045582791146617 1.156112557151452 1.2203896518484332 1.2227491299287176 1.2521682538525871 1.0 16.130495638975034 -5.275599935360277 23.616732621403084 1.096048365522645 1.3883058091161056 0.45676163816714777 0.12794615361416464 326.71184582635755 544885.5429603168 0.03757653171995584 0.07893344882781819 5.3015158558539985e-06 5.275599935360277 0.2922574435934606 EDSGSSS(ph)PPGVFLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDSGSSSPPGVFLEK 15 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 EDS(0.01)GS(0.003)S(0.438)S(0.55)PPGVFLEK 81.594 0.008661 4172600.0 28276.0 36783.0 36755.0 39636.0 40619.0 35396.0 45279.0 26889.0 33859.0 28389.0 True False 33062.568323543266 40434.57314962175 37631.378594113725 37415.32342164579 32659.998535931274 33539.77144890319 40989.845328428135 26183.192241250483 34354.12382006525 33535.700972799656 0.9858916725897532 1.2057172498770095 1.1221288806408436 1.1156863383291986 0.9738874569051456 1.0001213773973843 1.2222748933047332 0.7807557761350302 1.0244045248354703 1.0 15.033410137541077 -6.951389429129592 0.6964514484619925 0.9606722683541842 1.114973108234053 0.14547720626246796 0.11359428689893576 1.2533132999188983 1.290339488490896 0.08915540969485734 0.07580109509690627 1.1184345404728086e-07 6.951389429129592 0.15430083987986887 EDSGSSS(ph)PPGVFLEK ddPTM_PC-9_Lapatinib_30min_R1 2 EDSGSSSPPGVFLEK 15 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 EDS(0.008)GS(0.009)S(0.045)S(0.938)PPGVFLEK;EDS(0.059)GS(0.051)S(0.255)S(0.635)PPGVFLEK 116.78 0.00016629 4386000.0 40609.0 54642.0 52062.0 47784.0 53297.0 54175.0 46719.0 46771.0 61954.0 43108.0 True False 40029.90821322145 54515.479806194475 47781.66332513169 51298.19476275112 50162.17524593358 51858.06153809316 49137.88122217738 48944.151405930024 54976.08811545765 50559.16036220062 0.7917439278352589 1.078251288503432 0.9450644152875318 1.0146172206036677 0.9921481070210999 1.0256907188843198 0.9718887906792488 0.9680570455541421 1.0873615724947687 1.0 15.625684884374836 -4.749051441058356 24.999999999982176 1.005209490247088 0.7917434358808343 0.6918306194407876 0.04347161529078242 317.9499385894939 641613.4033002023 0.01009222614395775 0.17131442332406271 1.7821676617947774e-05 4.749051441058356 -0.21346605436625377 EDSGSVPSTGPSQGT(ph)PISLK ddPTM_PC-9_AZD4547_30min_R2 1 EDSGSVPSTGPSQGTPISLK 20 0 Q13111 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 EDSGSVPSTGPSQGT(0.965)PIS(0.035)LK 148.52 9.9723e-15 0.0 14215.0 17027.0 16434.0 13815.0 18876.0 17799.0 13100.0 23822.0 16255.0 15680.0 True False 18735.074309632153 22530.644768867176 16216.07442221515 10630.165189622321 16255.393223477122 16686.02571628109 14265.874621937332 20140.85727510177 17114.206114759796 15131.04797262056 1.2381874899566132 1.489033992201736 1.0717086120907113 0.7025399171860053 1.0743071631846683 1.1027673526958768 0.942821319960868 1.3310946678344024 1.1310654850693578 1.0 13.885224291264336 -5.3266688587843065 7.598905425057977 1.0428405815915371 1.362749890909759 0.3898905694296563 0.15974552686445712 0.27187584739867593 28.40809853297699 0.04395469661150111 0.09235633008726443 4.713365745207485e-06 5.3266688587843065 0.3199093093182219 EDSGTFS(ph)LGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EDSGTFSLGK 10 0 G5E9Q4;O75569 G5E9Q4 PRKRA Interferon-inducible double-stranded RNA-dependent protein kinase activator A 1 EDS(0.31)GT(0.043)FS(0.647)LGK;EDS(0.241)GT(0.058)FS(0.701)LGK 110.54 0.0017248 22430000.0 92378.0 157410.0 102269.0 109479.0 115772.0 87192.0 110255.0 72618.0 77047.0 99658.0 True False 108015.77085133278 173036.62451355177 104707.48081734206 103345.24656570693 93087.30767625572 82619.49802725634 99810.84822292575 70711.8544451309 78173.66661639656 117725.20650770594 0.9175245816558614 1.4698349626783225 0.8894227831359822 0.8778514782978296 0.7907168773593317 0.7017995591441015 0.8478290349517665 0.6006517766482092 0.6640350774095227 1.0 16.845063727780406 -5.462242161465428 5.754514536244218 0.7737828446617904 1.1963142626640446 0.4931371138599707 0.16375962324358329 0.15680043675551195 10.629985091780311 0.041508146992640584 0.08660445541872591 3.4495134173612727e-06 5.462242161465428 0.42253141800225424 EDSLPEESS(ph)APDFANLK ddPTM_PC-9_AZD4547_30min_R2 1 EDSLPEESSAPDFANLK 17 0 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 EDS(0.282)LPEES(0.273)S(0.445)APDFANLK 70.45100000000001 0.014704 2342900.0 6003.4 5575.2 7310.4 8953.5 9186.2 9123.0 7260.0 9260.4 8147.1 8641.2 True False 7912.356321522729 7377.274371021811 7213.459319469497 6889.40890519605 7910.8546953541845 8552.537367808998 7906.125935516409 7829.417962822276 8577.739073365707 8338.674218176584 0.9488746189742525 0.8847059110356992 0.8650606955894318 0.8261995522236094 0.9486945392482367 1.0256471405449845 0.9481274515177354 0.938928390529488 1.0286694082217542 1.0 13.025602309710237 -6.479170859037683 7.180115729125655 0.9825910270513563 0.880826661199837 0.624366402829407 0.03906222943868601 0.1722120270471871 23.903090536136336 0.012567027292084865 0.014054597224852606 3.3176391015525785e-07 6.479170859037683 -0.10176436585151927 EDSQRPGAHLTVK ddPTM_PC-9_AZD4547_30min_R2 1 EDSQRPGAHLTVK 13 1 F8VZ49;Q32P51;F8VYN5;F8W6I7;P09651-2;P09651;P09651-3;F8W646 F8VZ49;F8W6I7 HNRNPA1;HNRNPA1L2 Heterogeneous nuclear ribonucleoprotein A1-like 2;Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 0 66.498 0.016807 14131000.0 14846.0 17798.0 63486.0 109320.0 82896.0 66445.0 40513.0 84368.0 51854.0 65588.0 False True 19566.71918401679 23550.855441140444 62644.13415898451 84117.96297716348 71387.32128911646 62290.1836461766 44118.578515919595 71330.8641837707 54594.89657796086 63291.78408343341 0.30915101331672473 0.3720997248251826 0.9897672354504157 1.329050273986214 1.1279081846549186 0.9841748743259241 0.6970664384774011 1.127016171478748 0.8625905774119432 1.0 15.949730614884304 -5.2580008613006495 5.165318149868286 1.024168382200575 0.32907246903349874 0.7444135564091396 0.15818491929074138 0.08396379717149625 7.538503863782908 0.044182194193022786 0.10942354293489437 5.520763443919082e-06 5.2580008613006495 -0.6950959131670762 down EDSQRPGAHLTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDSQRPGAHLTVK 13 1 F8VZ49;Q32P51;F8VYN5;F8W6I7;P09651-2;P09651;P09651-3;F8W646 F8VZ49;F8W6I7 HNRNPA1;HNRNPA1L2 Heterogeneous nuclear ribonucleoprotein A1-like 2;Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 0 67.51899999999999 0.015744 9370100.0 22070.0 36647.0 75625.0 91585.0 102790.0 96325.0 80577.0 65239.0 77758.0 49388.0 False True 25806.015097630483 40285.071968414435 77428.18680940969 86453.78937257614 82649.03738418921 91273.54742952876 72944.16323303847 63526.545376434246 78895.06364631666 58341.65344480713 0.44232574111125783 0.6905027470043382 1.3271510531092328 1.4818536031784544 1.4166385850270349 1.5644662439311243 1.2502930398098115 1.0888711859449127 1.3522939270302587 1.0 15.832238653389604 -5.168637020883692 3.2480102304375476 1.3332203073203086 0.48378005467596785 0.772902594143977 0.16316010152401664 0.11408722595594141 2.25471877673045 0.0446659006251158 0.14820018444500835 6.782081105587999e-06 5.168637020883692 -0.8494402526443408 down EDSQRPGAHLTVK ddPTM_PC-9_Lapatinib_30min_R1 2 EDSQRPGAHLTVK 13 1 F8VZ49;Q32P51;F8VYN5;F8W6I7;P09651-2;P09651;P09651-3;F8W646 F8VZ49;F8W6I7 HNRNPA1;HNRNPA1L2 Heterogeneous nuclear ribonucleoprotein A1-like 2;Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 0 ; 71.558 0.011545 40288000.0 108415.0 131201.0 205396.0 171954.0 215599.0 227025.0 181175.0 165003.0 241501.0 141917.0 False True 106868.9822191238 130897.21214546567 188509.13373148796 184600.07078172878 202917.890703943 217315.66997112325 190555.35500391645 172669.64175306616 214300.6142617284 166447.16435748438 0.6420594945648792 0.7864189975885271 1.1325463816651171 1.1090610734903046 1.2191129328471417 1.3056135309363806 1.1448399000337073 1.0373840997508228 1.2874993400396266 1.0 17.34470476695018 -5.161612345527952 2.2440923094566663 1.1682950017242915 0.6343074816473092 0.7880324073979861 0.09270876178862415 0.14791763184242798 1.330696156401098 0.025237288252799753 0.11203049310434837 6.892672669087316e-06 5.161612345527952 -0.5339875200769822 EDSRGS(ph)LIPEGATGFPDQGNTGENTR ddPTM_PC-9_AZD4547_30min_R2 1 EDSRGSLIPEGATGFPDQGNTGENTR 26 1 A0A0J9YW64;A6NIW2;Q5JSL3 A0A0J9YW64 DOCK11 Dedicator of cytokinesis protein 11 1 EDS(0.382)RGS(0.618)LIPEGATGFPDQGNTGENTR 74.529 4.0334000000000004e-05 4859400.0 2748.7 2803.4 3768.1 8046.6 4178.4 5433.2 2926.7 6634.8 3704.6 4784.1 True False 3622.7294234882775 3709.544226525064 3718.132531967198 6191.580688730729 3598.301284434032 5093.461145103567 3187.1706302308376 5609.544112536526 3900.4175929092053 4616.610115166712 0.7847163466515639 0.8035212274777741 0.8053815330326918 1.3411530396274634 0.7794249881775197 1.1032902970017506 0.6903703260017973 1.215078590697486 0.8448661454202866 1.0 12.172618182813608 -5.576297326936927 24.999991036846602 0.9945096405492067 0.7966919017220814 0.1947963471852283 0.18493810983008874 141.08920201737746 66029.18637633402 0.04680178277856461 0.08106307473321409 2.6527887863673125e-06 5.576297326936927 -0.19781773882712528 EDSSGMHHENQTYPPY(ph)SPQAQPQPIHR ddPTM_PC-9_AZD4547_30min_R2 1 EDSSGMHHENQTYPPYSPQAQPQPIHR 27 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 EDSSGMHHENQT(0.009)Y(0.118)PPY(0.849)S(0.024)PQAQPQPIHR 89.024 1.6267e-07 8726300.0 4842.1 5635.0 21155.0 32071.0 29936.0 29675.0 15240.0 44805.0 28530.0 22962.0 True False 6381.787078063301 7456.40355156907 20874.470877568543 24677.526442010672 25779.903132973664 27819.41755888764 16596.330476208015 37881.416766473616 30038.03755485061 22158.107369088862 0.288011379842218 0.3365090450807612 0.9420692178199739 1.1137019074307972 1.1634523970642592 1.255496107835295 0.7489958505824522 1.7095962274882366 1.3556228902814351 1.0 14.435547038651418 -5.357773270571745 1.7875611455175962 1.2145966138455322 0.2254703137694391 0.6895709720155225 0.23292257131736854 0.2292872667246725 1.328711390542999 0.06953212832042154 0.2554960258724121 4.387596985495092e-06 5.357773270571745 -0.989126300076093 EDSSGMHHENQTYPPYS(ph)PQAQPQPIHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDSSGMHHENQTYPPYSPQAQPQPIHR 27 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 EDSSGMHHENQTY(0.003)PPY(0.451)S(0.546)PQAQPQPIHR 66.711 0.00013402 7111600.0 2219.6 4680.4 12435.0 7995.4 11404.0 10774.0 9918.4 4764.1 5859.4 6993.6 True False 2595.3344409017063 5145.039180313996 12731.497560000107 7547.443659436542 9169.468064298972 10208.99247345698 8978.857349002437 4639.047422981197 5945.082640104264 8261.484318692863 0.31414868573064625 0.622774187039557 1.5410666012151304 0.9135699310545569 1.109905642930491 1.2357334444559296 1.0868334312136148 0.5615271111130293 0.7196143466196034 1.0 13.012185294737105 -14.189890546047218 15.275225255223411 0.6452482216077967 0.9274147359145022 0.0 0.3437677205123927 0.0 0.0 0.0 0.0826442946667721 6.45816971865827e-15 14.189890546047218 0.2821665143067055 EDSSVASSDRS(ph)SVER ddPTM_PC-9_AZD4547_30min_R2 1 EDSSVASSDRSSVER 15 1 O14867 O14867 BACH1 Transcription regulator protein BACH1 1 EDSSVAS(0.004)S(0.004)DRS(0.864)S(0.128)VER 121.95 0.00027837 2322800.0 8371.3 5820.5 9630.6 10058.0 10802.0 10434.0 9534.5 12121.0 9265.4 7516.0 True False 11033.19926614306 7701.862798918858 9502.891951477744 7739.283494550944 9302.328756092384 9781.56033056221 10383.052029226068 10247.977962870815 9755.150128311005 7252.867127692349 1.5212189982106432 1.0619059557167658 1.3102255679267198 1.0670653905958647 1.2825726147077665 1.3486473912109869 1.4315789668312389 1.4129554261021493 1.3450060447219043 1.0 12.82433570368182 -6.52220760225838 18.2071574897578 1.338351882422743 1.22518868933633 0.016253297120277566 0.16595743218210968 1.9025393751337853 51592.120112503675 0.05103960569083471 0.05210114059169281 3.00463967582333e-07 6.52220760225838 -0.11316319308641298 EDSSVASSDRSS(ph)VER ddPTM_PC-9_AZD4547_30min_R2 1 EDSSVASSDRSSVER 15 1 O14867 O14867 BACH1 Transcription regulator protein BACH1 1 EDS(0.002)S(0.012)VAS(0.001)S(0.003)DRS(0.223)S(0.759)VER 102.39 0.012980000000000002 0.0 5926.1 6641.4 7637.4 10046.0 12042.0 9924.6 9956.5 10688.0 6739.4 9455.6 True False 7810.476529462612 8788.102670344422 7536.123085811489 7730.04990915279 10370.176160050401 9304.013193089688 10842.609211703739 9036.415185806716 7095.630925242209 9124.562322060649 0.8559836903715433 0.9631259407475622 0.825916117378172 0.8471693913979506 1.1365121738473094 1.019666792191794 1.188288142379096 0.9903395765032129 0.7776406883743838 1.0 13.155539643439484 -6.2401723566053375 24.454884369730614 1.026781839239429 0.876116232474926 0.3077638651512604 0.10659562379448537 796.1810624463847 915525.3292736553 0.032698854090576095 0.042165821713826886 5.752116102453694e-07 6.2401723566053375 -0.15066560676450302 EDTDS(ph)MSR ddPTM_PC-9_Lapatinib_30min_R1 1 EDTDSMSR 8 0 F8VW98;P37288 F8VW98 AVPR1A Vasopressin V1a receptor 1 EDT(0.052)DS(0.947)MS(0.001)R 70.816 0.037106 1586300.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 EDTEEHHLR ddPTM_PC-9_AZD4547_30min_R2 4 EDTEEHHLR 9 0 F8VZ49;Q32P51;F8VYN5;F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;A0A2R8Y4L2;P22626;P22626-2;A0A087WUI2 F8VZ49;F8W6I7;P22626 HNRNPA1;HNRNPA1L2;HNRNPA2B1 Heterogeneous nuclear ribonucleoprotein A1-like 2;Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed;Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;;; 164.68 0.00044625 261414790.0 209111.18 239719.4 274459.9 235674.6 262409.3 273463.1 255587.09000000003 321266.5 253273.91 257844.5 False True 275604.1854572542 317204.00808163354 270820.3823970871 181343.46210627307 225978.29820922672 256363.4091271383 278333.8458721996 271622.14439473936 266661.4518136651 248817.4425367578 1.1076562103018126 1.2748463485825476 1.0884300539222802 0.7288213408892473 0.9082092312553327 1.0303273215633415 1.1186267451128606 1.0916523440860164 1.0717152668035772 1.0 17.924728098889375 -5.522020675513743 24.999880974138595 0.9928509200588952 1.1888480475006087 0.3390307679985016 0.11140920569501873 35.78489139108887 1042587.9984148629 0.03347133480739534 0.05892580576323256 3.0059331953701887e-06 5.522020675513743 0.1959971274417135 EDTEEHHLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EDTEEHHLR 9 0 F8VZ49;Q32P51;F8VYN5;F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;A0A2R8Y4L2;P22626;P22626-2;A0A087WUI2 F8VZ49;F8W6I7;P22626 HNRNPA1;HNRNPA1L2;HNRNPA2B1 Heterogeneous nuclear ribonucleoprotein A1-like 2;Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed;Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;;; 164.68 0.00010467 233366800.0 667171.23 942295.0 971404.5 725792.4 916428.0 715542.4 812272.92 540186.2 609922.8 580647.4 False True 780110.142006557 1035839.8201892949 994566.4673520827 685128.6048787097 736860.5120334441 678018.096903596 735328.5486709225 526006.884624589 618841.7670894263 685914.1772177104 1.1373290827300522 1.5101595135283483 1.4499867481765223 0.9988547075347133 1.0742750864581754 0.988488238650871 1.0720416242942417 0.7668698243827572 0.9022145738401974 1.0 19.387668549598565 -5.781011128084395 10.98348595751242 0.9710845446973612 1.3802686523675312 0.684537460725714 0.12245266790961117 0.24095884819475874 132.97304318459408 0.035510948180110934 0.05368302620692395 1.65572753762117e-06 5.781011128084395 0.40918410767017 EDTEEHHLR ddPTM_PC-9_Lapatinib_30min_R1 4 EDTEEHHLR 9 0 F8VZ49;Q32P51;F8VYN5;F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;A0A2R8Y4L2;P22626;P22626-2;A0A087WUI2 F8VZ49;F8W6I7;P22626 HNRNPA1;HNRNPA1L2;HNRNPA2B1 Heterogeneous nuclear ribonucleoprotein A1-like 2;Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed;Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;;; 164.46 0.00039694 277403710.0 259732.87 392303.9 361282.1 319970.2 394422.4 369813.30000000005 353156.33 402756.1 389949.2 319320.9 False True 256029.0316446253 391395.5444226297 331578.88032723655 343501.8758972972 371223.2498962738 353997.2472359076 371441.03676020616 421469.6187394313 346029.0147488812 374515.0920966468 0.6836280754703333 1.0450728226504336 0.8853551894823769 0.9171910108462429 0.9912103883933107 0.9452149051033586 0.991791905316202 1.125374190876846 0.9239387732326299 1.0 18.514664331583525 -4.7535471406206495 24.988856004704804 0.979112038426117 0.683627537837249 0.6469069682019576 0.0658062235710138 187.82963841556753 594669.1284651087 0.016732986874726265 0.17832741518000636 1.7638143003499256e-05 4.7535471406206495 -0.295484500588868 EDTEEYNLR ddPTM_PC-9_AZD4547_30min_R2 1 EDTEEYNLR 9 0 P51991;P51991-2 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 0 134.26 0.0051847 9287700.0 24467.0 32898.0 28364.0 24942.0 24611.0 30585.0 34084.0 37451.0 23208.0 25496.0 False True 32246.997054785053 43531.63514454644 27987.874827291642 19192.007250058618 21194.187466782965 28672.515115032147 37117.40997054289 31663.8084883652 24434.727499928962 24603.392800378417 1.3106727725083946 1.769334640053257 1.1375615978809708 0.7800553121179056 0.8614335282431854 1.1653886660132153 1.5086297354067362 1.28696918938262 0.9931446324570788 1.0 14.586569656039618 -5.352921398782214 7.432191064853975 1.0982998848174954 1.5380464805446807 0.39536203233254996 0.22192967459080673 0.27638846535532574 19.524084003771268 0.06414198628128244 0.13449451933105472 4.436889381479216e-06 5.352921398782214 0.43974659572718533 EDTEEYNLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDTEEYNLR 9 0 P51991;P51991-2 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 0 105.1 0.01225 6726800.0 26042.0 28953.0 28904.0 31326.0 26421.0 19748.0 28014.0 20397.0 16659.0 17472.0 False True 30450.396247054527 31827.26249628902 29593.180979030407 29570.905780262292 21243.994714735454 18712.38011563285 25360.311116203655 19861.600362407895 16902.606359268346 20639.5352917241 1.4753431129461678 1.5420532510269696 1.4338104303586952 1.4327311813129548 1.0292864841416136 0.9066279764126286 1.2287249086646084 0.9623085055782173 0.8189431651615644 1.0 14.33312286775865 -6.250365082543548 3.790527946814946 0.9922956480667987 1.4819385252364483 0.8472489335863421 0.1001394082786913 0.08848586818773814 2.875396874996451 0.032463488282544695 0.04040281978975545 5.618688008028504e-07 6.250365082543548 0.4896428771696496 EDTEEYNLR ddPTM_PC-9_Lapatinib_30min_R1 3 EDTEEYNLR 9 0 P51991;P51991-2 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 0 ;; 159.58 0.00058007 31529100.0 68801.0 93573.0 95057.0 80926.0 104218.0 94883.0 103930.0 104257.0 90460.0 94734.0 False True 67819.88512344181 93356.3374676082 87241.7803906311 86877.56800122233 98088.1021404714 90825.0752730759 109310.98686660443 109101.16082889089 80271.4422139699 111108.64567487952 0.6103925100652646 0.8402256809140017 0.7851934461150176 0.7819154618753887 0.8828125079257273 0.8174438156580868 0.9838207117244926 0.981932235481811 0.7224590105153124 1.0 16.761611555673078 -3.1156791312104772 0.31576214842746797 0.9315585135061946 1.3839579479630587e-18 0.45635425208606806 0.08776320024792124 20.292571343956052 0.7096977717600413 0.0860061965488015 8.913628738492983 0.0007661624598931946 3.1156791312104772 -0.9315585135061946 EDTQVDSEARPMKDETFGEYRSLES(ph)DNEEK ddPTM_PC-9_AZD4547_30min_R2 1 EDTQVDSEARPMKDETFGEYRSLESDNEEK 30 3 P32004 P32004 L1CAM Neural cell adhesion molecule L1 1 EDT(0.002)QVDS(0.011)EARPMKDET(0.138)FGEY(0.129)RS(0.138)LES(0.583)DNEEK 40.104 0.030712 8399600.0 10687.0 9335.5 15834.0 27556.0 29254.0 23779.0 20397.0 19357.0 20061.0 24374.0 True False 14085.243696590825 12353.017809347482 15624.030814248197 21203.38993595603 25192.587060796748 22292.095370944888 22212.29348577523 16365.820429608957 21121.383504656802 23520.67367886819 0.5988452494558228 0.5251982990795827 0.6642679979139111 0.9014788532611595 1.07108271662434 0.9477660238521527 0.9443731837379958 0.6958057687060466 0.8979922851288484 1.0 14.52164176197047 -5.673665324127029 3.375640880949301 0.9197405986316801 0.5675218767794258 0.7313957784216916 0.09201773848394434 0.13194575097952926 2.9566422643429093 0.02844238208074075 0.05206426625826933 2.119994215181331e-06 5.673665324127029 -0.35221872185225434 EDVEVAES(ph)PLR ddPTM_PC-9_AZD4547_30min_R2 2 EDVEVAESPLR 11 0 Q99567;J3KMX1 Q99567 NUP88 Nuclear pore complex protein Nup88 1 EDVEVAES(1)PLR;EDVEVAES(1)PLR 179.59 0.00027039999999999996 140007000.0 71032.0 72285.0 91593.0 118225.0 94534.0 85174.0 80723.0 120397.0 74405.0 64779.0 True False 93618.6984426165 95649.71263978184 90378.41697419692 90970.05280804182 81409.58587561909 79848.05631544063 87907.19061882785 101792.41009782672 78337.89639918196 62511.10692719301 1.497633029465542 1.5301234827146082 1.445797737663822 1.45526222906267 1.3023219372908759 1.277341903550677 1.4062651413486211 1.6283891791643497 1.2531836380760701 1.0 15.931824929086389 -12.822799709798815 0.2647947099280041 3.4866972742570494e-15 1.4632026081238843 0.5953770118244832 0.107538310580073 56.35364406747974 1.2430013107339035 31.206964255368295 0.1509753796821884 1.5038353528432378e-13 12.822799709798815 1.4632026081238807 EDVEVAES(ph)PLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDVEVAESPLR 11 0 Q99567;J3KMX1 Q99567 NUP88 Nuclear pore complex protein Nup88 1 EDVEVAES(1)PLR 113.95 0.0015065 61718000.0 29962.0 31001.0 32373.0 43660.0 38928.0 28940.0 37251.0 29239.0 32661.0 25617.0 True False 35033.974823525365 34078.57440152852 33144.89509528617 41213.87174762981 31300.337846986193 27422.335454041662 33722.3156061149 28471.50723128131 33138.605336458604 30261.159315939563 1.1577208413516331 1.1261490032729249 1.0952949538132086 1.3619396176246654 1.0343403410357535 0.9061891901675229 1.1143761960352996 0.9408597646252242 1.0950871045777613 1.0 14.885179638330756 -6.492584294551013 24.93376494948668 1.0091834389564198 1.1775648494044337 0.4729939589339254 0.08809369783576847 587.9636514416111 483922.33086869895 0.026492155838293636 0.029996458857792598 3.216738118103165e-07 6.492584294551013 0.1683814104480139 EDVEVAES(ph)PLR ddPTM_PC-9_Lapatinib_30min_R1 1 EDVEVAESPLR 11 0 Q99567;J3KMX1 Q99567 NUP88 Nuclear pore complex protein Nup88 1 EDVEVAES(1)PLR 144.51 0.00017885 67499000.0 43685.0 47351.0 53533.0 55465.0 47509.0 45439.0 44870.0 41395.0 38330.0 41406.0 True False 43062.04388915217 47241.36166873676 49131.72338335586 59544.08112581601 44714.61402628778 43495.6798934825 47193.14904940383 43318.36281987715 34012.87176720614 48562.971929973035 0.88672587730518 0.9727856387549343 1.0117116278262985 1.2261210292417348 0.9207553049011391 0.8956552320603961 0.9717928531527176 0.8920039507125198 0.700386949469487 1.0 15.56756909310014 -6.5001154966131836 24.975232151622865 0.8922068766805805 1.0264628860388378 0.2530928759005372 0.10828146385556588 1105.9874852821617 1213461.5515211995 0.03477993207077038 0.03914694844686725 3.1614367933968036e-07 6.5001154966131836 0.13425600935825732 EDVEVAES(ph)PLRVLAETPDSFEK ddPTM_PC-9_AZD4547_30min_R2 1 EDVEVAESPLRVLAETPDSFEK 22 1 Q99567;J3KMX1 Q99567 NUP88 Nuclear pore complex protein Nup88 1 EDVEVAES(0.999)PLRVLAET(0.001)PDSFEK 67.214 0.0012052 1994900.0 8314.3 3839.8 7047.4 17290.0 11865.0 7199.6 4070.1 6850.2 3360.3 9880.2 True False 10958.07445181671 5080.940258618444 6953.946871310645 13304.05762783712 10217.749554808015 6749.407873865798 4432.331015171537 5791.65899193611 3537.918597811584 9534.297205298833 1.1493321653248434 0.5329118810975007 0.7293612441036431 1.3953894389240546 1.0716835582940862 0.7079082735237905 0.46488282457863805 0.6074552604377915 0.3710728249424961 1.0 13.218910882791274 -6.935434288837046 5.0527569585911944 0.578544612090311 0.9588344211145458 0.29694800061102544 0.26626335224763553 0.2637205029297141 13.186712154985015 0.0998155510932514 0.08705384317854414 1.1602877608384303e-07 6.935434288837046 0.3802898090242347 EDVEVAES(ph)PLRVLAETPDSFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EDVEVAESPLRVLAETPDSFEK 22 1 Q99567;J3KMX1 Q99567 NUP88 Nuclear pore complex protein Nup88 1 EDVEVAES(1)PLRVLAETPDSFEK 79.383 0.00027341 1512600.0 7717.3 2220.0 4904.4 10305.0 11424.0 12164.0 8593.6 15335.0 12222.0 7543.6 True False 9023.68646637716 2440.386928531124 5021.339496040578 9727.644259260775 9185.549207870172 11526.098426501829 7779.551995723848 14932.47249877556 12400.723628247668 8911.194964895256 1.012623615791715 0.27385630525925864 0.5634866609721404 1.0916206297339288 1.0307875929160686 1.2934402705706383 0.8730088418411448 1.6756981030715312 1.3915893072813528 1.0 13.121403190520802 -5.856159293331412 3.197445312072357 1.2230780720444088 0.5768401932748993 0.48893446585087286 0.2708310439446615 0.19779506701436977 4.021474980460658 0.0799614776199929 0.12919097457203582 1.392645905607645e-06 5.856159293331412 -0.6462378787695094 EDVFVHQTAIK ddPTM_PC-9_Lapatinib_30min_R1 2 EDVFVHQTAIK 11 0 H0Y449;P67809;Q9Y2T7;P16989-2;P16989;P16989-3;A0A0D9SEI8 H0Y449;P16989-2 YBX1;YBX2;YBX3 Nuclease-sensitive element-binding protein 1;Y-box-binding protein 2;Y-box-binding protein 3 0 ; 95.48299999999999 0.0052036999999999995 2246400.0 40749.0 39891.0 47250.0 51149.0 52350.0 56678.0 59418.0 48351.0 56397.0 48067.0 False True 40167.91178754859 39798.63484039575 43365.28739027448 54910.6680880621 49270.87592405994 54254.01406287114 62494.373305493136 50597.56397400361 50044.975973261826 56375.31690474849 0.7125088423966845 0.7059585120849851 0.7692247205198739 0.9740196792301663 0.8739795823641722 0.9623717797371942 1.1085414102608662 0.897512719254298 0.8877107699069366 1.0 15.782776017817673 -5.669200286247267 3.674780982083257 0.9571714947008403 0.7138798526621187 0.7305134940779185 0.06409199431357057 0.12267993054273366 3.1800195876288684 0.019021982378254396 0.03444022562103628 2.141902578975056e-06 5.669200286247267 -0.24329164203872156 EDVSNFDDEFTSEAPILT(ph)PPREPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EDVSNFDDEFTSEAPILTPPREPR 24 1 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 EDVSNFDDEFT(0.008)S(0.036)EAPILT(0.956)PPREPR;EDVSNFDDEFTSEAPILT(0.999)PPREPR 78.354 0.00013615 726350.0 1931.35 2480.4 3013.9 3095.1000000000004 3627.5 2378.71 4104.0 2359.8 1257.01 1538.8600000000001 True False 2258.289409098715 2726.6377196074773 3085.7628062793997 2921.691581449589 2916.7174152266325 2253.966260120368 3715.2394096130433 2297.8577504147747 1275.391393220717 1817.8431363909438 1.242290582663921 1.4999301452493912 1.6974857425848753 1.6072297564960263 1.6044934553689487 1.2399124077313304 2.0437623770932714 1.264057224968722 0.7015959560475697 1.0 10.828011997882387 -8.003682002070088 24.93937101583631 0.8948073769151912 1.562935181393405 0.6097953814667346 0.2263868794442334 89.04741749665843 603142.4438662007 0.12349307245042347 0.05727541971618058 9.915577148555264e-09 8.003682002070088 0.6681278044782137 EDYDSVEQDGDEPGPQR ddPTM_PC-9_Lapatinib_30min_R1 1 EDYDSVEQDGDEPGPQR 17 0 Q9Y5S9;Q9Y5S9-2 Q9Y5S9 RBM8A RNA-binding protein 8A 0 171.36 3.0225e-24 0.0 4703.7 4009.3 5164.0 4492.2 6034.8 5491.6 3356.4 3898.0 5388.9 4441.5 False True 4636.624375447064 4000.01671218066 4739.435853616456 4822.5713735399 5679.844928873298 5256.737069544853 3530.177969008673 4079.1153103486167 4781.945334367265 5209.2073570732555 0.8900825130624304 0.7678743497797776 0.9098190048397813 0.9257783464871356 1.0903472523820719 1.0091241736436274 0.6776804467603437 0.7830587324979188 0.9179794557177997 1.0 12.346848150636703 -10.393176285872444 16.858116556554698 0.999999984791099 0.8846739734513893 0.08395829093753382 0.1131652901316268 0.0 0.0 0.12056804195076216 0.029242045413934922 4.044117023192761e-11 10.393176285872444 -0.11532601133970966 EEAENTLQSFR ddPTM_PC-9_Lapatinib_30min_R1 2 EEAENTLQSFR 11 0 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 0 ; 173.24 0.0018169 16564400.0 27821.0 34337.0 33355.0 24702.0 30435.0 31846.0 33192.0 26564.3 32288.0 25096.0 False True 27424.267438253453 34257.494786158975 30612.68065402341 26518.667483456346 28644.87313751222 30484.020816651857 34910.5193502967 27798.574355744942 28651.385432286796 29433.810161681955 0.9317267213320347 1.1638824398873333 1.040051576260968 0.9009593843878 0.9731962318219745 1.035680418172198 1.1860686454975011 0.9444436246291408 0.973417484005732 1.0 14.845186688581595 EEAGAAVVT(ph)AGEAELNWSR ddPTM_PC-9_Lapatinib_30min_R1 1 EEAGAAVVTAGEAELNWSR 19 0 Q96CX6 Q96CX6 LRRC58 Leucine-rich repeat-containing protein 58 1 EEAGAAVVT(1)AGEAELNWSR 71.354 0.040912000000000004 0.0 7984.3 8423.4 10539.0 9149.0 14935.0 11318.0 12742.0 12241.0 12578.0 10366.0 True False 7870.4424178587005 8403.896134832157 9672.524101716468 9821.847980169303 14056.552663339746 10833.955523546618 13401.71841291517 12809.76154796753 11161.333187788128 12157.749288173223 0.6473601512341502 0.6912378217082723 0.7955850932972993 0.807867290841716 1.1561805010252708 0.8911152275598937 1.1023190308712856 1.0536293555936844 0.9180427168905033 1.0 13.569588553122692 -5.89812206133534 1.8957510797529482 1.0203901624272274 0.6860740885379261 0.7358303498972558 0.08397878537575491 0.1635090037698041 1.1956815903183804 0.025618209474770722 0.0452468317352002 1.2643809349071532e-06 5.89812206133534 -0.3343160738893013 EEAIEHNYGGHDDDLSVR ddPTM_PC-9_AZD4547_30min_R2 2 EEAIEHNYGGHDDDLSVR 18 0 H3BND8;A0A669KBL1;Q93009-3;Q93009;F5H2X1 H3BND8 USP7 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 7 0 ; 129.88 1.7531e-05 7476600.0 25285.0 21329.0 33748.0 35960.0 34824.0 35943.0 26759.0 36447.0 30719.0 30026.0 False True 33325.1040393281 28223.182138671986 33300.479469448546 27669.977576461715 29989.288705995285 33695.47852802356 29140.499160948177 30814.953618740423 32342.743625918538 28974.798879203096 1.1501409959137792 0.9740596390793039 1.1492911342811853 0.954967028134303 1.0350128341191127 1.162923638176097 1.0057187724558811 1.063508801120898 1.1162370362174563 1.0 14.82251102673518 EEAIEHNYGGHDDDLSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEAIEHNYGGHDDDLSVR 18 0 H3BND8;A0A669KBL1;Q93009-3;Q93009;F5H2X1 H3BND8 USP7 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 7 0 53.21 0.020931 4092800.0 12450.0 13792.0 17586.0 19094.0 21819.0 16026.0 17566.0 12607.0 16090.0 13688.0 False True 14557.539101291324 15161.178611847417 18005.31693527641 18024.225083583227 17543.723579002042 15185.568347839391 15902.02131317319 12276.079608220649 16325.285810710586 16169.52604585162 0.9003070999119446 0.9376390234849895 1.113533995011299 1.1147033643702524 1.0849868777386322 0.939147400163614 0.9834562415793838 0.7592108496816543 1.0096329208671473 1.0 13.980989771328211 -6.870919807260333 6.3616189106603755 0.9241530083771935 1.0341350293613063 0.1895229745653061 0.09298006714324115 0.33739324541100363 17.71771063915677 0.034702663072760376 0.030632358580083244 1.3461088909326953e-07 6.870919807260333 0.1099820209841128 EEAIEHNYGGHDDDLSVR ddPTM_PC-9_Lapatinib_30min_R1 2 EEAIEHNYGGHDDDLSVR 18 0 H3BND8;A0A669KBL1;Q93009-3;Q93009;F5H2X1 H3BND8 USP7 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 7 0 ; 86.005 0.00075176 8697200.0 14124.3 22000.0 30146.0 19229.1 27599.0 27012.0 24935.0 29897.0 24111.5 21415.7 False True 13922.884891920605 21949.06035167596 27667.512246925173 20643.272160397162 25975.681081721712 25856.759728047473 26226.012292107982 31286.12376436446 21395.808964648862 25117.375210373477 0.554312891984448 0.8738596357238393 1.101528802878196 0.8218721895698516 1.0341717979748837 1.0294371729323306 1.0441382537963855 1.2455968628220073 0.8518329955039408 1.0 14.616398088650357 -4.815020401373243 2.646093770101387 1.0201788247936612 0.47893168825582844 0.605132207335813 0.11296831341712642 0.2842429137331059 2.7969413826348357 0.02877562044169898 0.33526929933137 1.5310155391630716e-05 4.815020401373243 -0.5412471365378327 EEAKES(ph)PSAAGPEDK ddPTM_PC-9_Lapatinib_30min_R1 1 EEAKESPSAAGPEDK 15 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3;H0YF21 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 EEAKES(0.5)PS(0.5)AAGPEDK 56.428000000000004 0.031401 5209600.0 12548.0 23333.0 26920.0 28464.0 25043.0 23978.0 22126.0 20921.0 25464.0 23458.0 True False 12369.063218978617 23278.973872075258 24706.741514205085 30557.33751312047 23570.019976432348 22952.516835448037 23271.57601665052 21893.066035865442 22595.976172192488 27512.684044179772 0.4495767551837697 0.8461178791096485 0.8980127665672708 1.1106636293300793 0.8566964945544278 0.8342521870491068 0.8458489902068844 0.7957444646516361 0.8212930492680376 1.0 14.74780927050635 -4.75950480257326 4.1007360471030765 0.889593484952525 0.40236930499649104 0.6860951915499651 0.08981980154168973 0.15062600077270089 4.871735709528753 0.024124070202893654 0.22432045282256008 1.7397834588260378e-05 4.75950480257326 -0.48722417995603395 EEAPAS(ph)PLRPLYPQIS(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 3 EEAPASPLRPLYPQISPLK 19 1 P85037;P85037-2;U3KQ26 P85037;U3KQ26 FOXK1 Forkhead box protein K1 2 EEAPAS(1)PLRPLY(0.005)PQIS(0.995)PLK;EEAPAS(1)PLRPLY(0.001)PQIS(0.999)PLK;EEAPAS(1)PLRPLY(0.003)PQIS(0.997)PLK 81.525 0.006876100000000001 43929000.0 318191.0 345984.0 338229.0 266839.0 327863.0 387954.0 407363.0 432294.0 429691.0 366014.0 True False 419369.1192160514 457816.56191412103 333743.86246509705 205323.39117145364 282344.8817773303 363695.17505107645 443617.5178333023 365492.895427875 452403.5890284368 353199.96126599074 1.1873419173458784 1.2961965235589161 0.9449147765159535 0.5813233683138119 0.7993910326753962 1.0297146515743298 1.2559953750935413 1.0348044606738407 1.2808710040818407 1.0 18.430125659208677 -7.007544492046826 24.361889489409737 1.1453948087753894 0.9539521569242129 0.15428587749211087 0.19959488383099058 531.4856183937152 1716222.451309824 0.08142160151856385 0.06881829305784455 9.827781854372665e-08 7.007544492046826 -0.19144265185117648 EEAPAS(ph)PLRPLYPQIS(ph)PLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEAPASPLRPLYPQISPLK 19 1 P85037;P85037-2;U3KQ26 P85037;U3KQ26 FOXK1 Forkhead box protein K1 2 EEAPAS(1)PLRPLY(0.128)PQIS(0.872)PLK 64.454 0.036313 4730500.0 57164.0 64710.0 65603.0 63912.0 62746.0 50580.0 69508.0 55751.0 50173.0 53232.0 True False 66840.73615953565 71133.98114650864 67167.22432076282 60331.217845499676 50451.371725929814 47927.49575899887 62923.69904565874 54287.59532306725 50906.68520700949 62882.540215719826 1.0629458658991375 1.1312199046425617 1.0681378979020932 0.9594271738789847 0.8023112862943412 0.7621749311427723 1.0006545351030305 0.8633174667695128 0.8095519842610218 1.0 15.940371877721663 -5.882676099589433 2.9167823769770345 0.8674425832354536 1.0958502994588943 0.6149698947227863 0.07571121988951064 0.16534086628770173 2.8274112273596472 0.0225895603508566 0.036428897396785107 1.3101586858811137e-06 5.882676099589433 0.2284077162234407 EEAPAS(ph)PLRPLYPQIS(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 3 EEAPASPLRPLYPQISPLK 19 1 P85037;P85037-2;U3KQ26 P85037;U3KQ26 FOXK1 Forkhead box protein K1 2 EEAPAS(1)PLRPLY(0.047)PQIS(0.953)PLK;EEAPAS(1)PLRPLY(0.059)PQIS(0.941)PLK;EEAPAS(1)PLRPLYPQIS(1)PLK 79.845 0.0085651 39215400.0 178243.0 279207.0 234707.0 245423.0 283916.0 248649.0 273224.0 270365.0 246223.0 249161.0 True False 175701.22213423735 278560.5133459265 215410.29645522014 263472.2261271282 267216.6190803325 238014.86189912932 287370.20182470075 282927.1449159583 218490.772896864 292228.1468638371 0.6012467451196782 0.9532295787911251 0.7371305562690714 0.9015977035569142 0.9144109557825769 0.8144830142252919 0.9833761905166518 0.9681721215163692 0.7476718969123435 1.0 18.156735616935514 -4.7532146579304175 24.999458416902847 0.8868558329626774 0.601246218504251 0.4818642824973812 0.09007767731717597 265.6841987387839 807498.0056759361 0.02152193836793409 0.2362769283454944 1.765165140125386e-05 4.7532146579304175 -0.2856096144584265 EEAPAS(ph)PLRPLYPQISPLK ddPTM_PC-9_AZD4547_30min_R2 2 EEAPASPLRPLYPQISPLK 19 1 P85037;P85037-2;U3KQ26 P85037;U3KQ26 FOXK1 Forkhead box protein K1 1 EEAPAS(0.999)PLRPLY(0.001)PQISPLK;EEAPAS(0.999)PLRPLY(0.001)PQISPLK 81.01 0.0010838 123842000.0 266636.0 294190.0 311270.0 320180.0 312080.0 407180.0 291400.0 451860.0 358110.0 335840.0 True False 351420.70162666816 389281.1643009952 307142.3564197948 246367.44773168833 268753.07889291935 381718.9702317732 317334.03548339993 382035.41970982595 377038.963503945 324082.34382174053 1.0843562086182792 1.2011797980426753 0.9477293727199668 0.7602001541534185 0.829274053389176 1.1778456232152386 0.9791771799143354 1.1788220709733022 1.1634048280992837 1.0 18.306000898441283 -6.778184074834173 24.97099739914755 1.1034842594931953 0.9654070755531214 0.21024880944434998 0.131015054257236 442.3497805536421 659662.357305788 0.051670714206210874 0.045690338735537815 1.66654070294284e-07 6.778184074834173 -0.13807718394007384 EEAPAS(ph)PLRPLYPQISPLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EEAPASPLRPLYPQISPLK 19 1 P85037;P85037-2;U3KQ26 P85037;U3KQ26 FOXK1 Forkhead box protein K1 1 EEAPAS(0.982)PLRPLY(0.017)PQIS(0.001)PLK;EEAPAS(0.987)PLRPLY(0.013)PQIS(0.001)PLK;EEAPAS(0.969)PLRPLY(0.029)PQIS(0.002)PLK;EEAPAS(0.946)PLRPLY(0.047)PQIS(0.007)PLK 75.773 0.0018557000000000003 106674600.0 316947.0 450509.0 431519.0 435642.0 423151.0 338894.0 468293.0 296082.0 329449.0 306791.0 True False 370599.8671114039 495232.5562097434 441808.04950492 411234.39111041976 340237.5991648703 321121.802051209 423932.8968922801 288310.1612248106 334266.56836872525 362409.7797437808 1.0225989689721215 1.3664988747264675 1.2190842361298109 1.1347221131867837 0.9388201372639945 0.8860737761498547 1.16976119461234 0.7955363716416325 0.9223442275896847 1.0 18.467262361933216 -6.1209077890267265 3.134645179700082 0.9489435239696691 1.2161885509962245 0.48710344199561284 0.11846343801473058 0.21158262899956018 3.940003446499131 0.036054121990805994 0.049045774885848444 7.569936055760004e-07 6.1209077890267265 0.2672450270265554 EEAPAS(ph)PLRPLYPQISPLK ddPTM_PC-9_Lapatinib_30min_R1 1 EEAPASPLRPLYPQISPLK 19 1 P85037;P85037-2;U3KQ26 P85037;U3KQ26 FOXK1 Forkhead box protein K1 1 EEAPAS(0.799)PLRPLY(0.173)PQIS(0.028)PLK 54.223 0.015875 65678000.0 169950.0 240740.0 240880.0 189420.0 233120.0 242470.0 280690.0 235300.0 271970.0 211390.0 True False 167526.48183498738 240182.58132102183 221075.77622368917 203350.57868659662 219408.33993155404 232100.12332517662 295222.754773282 246232.8970048816 241337.8746289344 247928.4798405309 0.6757048724000624 0.9687575282819817 0.8916917345110431 0.8201985460379257 0.8849662615310626 0.9361575704189564 1.190757733694697 0.9931610001531898 0.9734173128644373 1.0 17.91956447948271 -6.972452404826799 4.104633932562557 1.0421682652618005 0.8575536140523823 0.497792999740594 0.08975349686825347 0.1858893808555282 7.075596027156198 0.03323531902056382 0.028013527484892314 1.0654856259022003e-07 6.972452404826799 -0.18461465120941822 EEAPASPLRPLYPQIS(ph)PLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEAPASPLRPLYPQISPLK 19 1 P85037;P85037-2;U3KQ26 P85037;U3KQ26 FOXK1 Forkhead box protein K1 1 EEAPAS(0.322)PLRPLY(0.02)PQIS(0.658)PLK 61.256 0.008439799999999999 9515300.0 25200.0 31397.0 28661.0 23724.0 21426.0 21133.0 23045.0 16082.0 16893.0 15615.0 True False 29465.862277312575 34513.8866644557 29344.386937447784 22394.821194245746 17227.729107827952 20024.7482774797 20862.010768648306 15659.864540287497 17140.02816658384 18445.87589172802 1.5974227762492115 1.871089606535481 1.5908372749383592 1.2140828294463704 0.9339610224502084 1.0855948719930246 1.1309850988428145 0.8489629135643323 0.9292065211319251 1.0 14.171010675746734 -5.814443713671333 2.364175735273851 0.9932505394404982 1.739062272514355 0.9090415789622515 0.09922169118633954 0.07830373428855944 0.8924110604403921 0.030478917168211245 0.05414635139537267 1.5330498829790605e-06 5.814443713671333 0.7458117330738567 EEAS(ph)DDDMEGDEAVVR ddPTM_PC-9_AZD4547_30min_R2 2 EEASDDDMEGDEAVVR 16 0 O75643;A0A494C1A5;O75643-2 O75643 SNRNP200 U5 small nuclear ribonucleoprotein 200 kDa helicase 1 EEAS(1)DDDMEGDEAVVR;EEAS(1)DDDMEGDEAVVR 132.65 4.9582e-05 0.0 11369.7 13398.099999999999 16726.7 14470.400000000001 14961.6 15762.2 14735.7 18858.2 12195.2 15556.1 True False 14985.028095548687 17728.773810874467 16504.893028968374 11134.472845451379 12884.440096014796 14776.5871422645 16047.148753166563 15944.098508325253 12839.81337500576 15011.485673908324 0.9982375110009515 1.1810139379934326 1.0994843140446626 0.7417302382537901 0.8583054586268849 0.9843520796844175 1.0689913777860334 1.0621266178895215 0.8553326202297766 1.0 13.873779145869307 -5.592172379858992 24.999974531490118 0.9433650774910434 1.1022995981723467 0.31556878661507026 0.10365329283955346 58.84308053631826 21228.582664153153 0.03014850497951798 0.05221875011789585 2.5575705363221276e-06 5.592172379858992 0.15893452068130332 EEAS(ph)DDDMEGDEAVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EEASDDDMEGDEAVVR 16 0 O75643;A0A494C1A5;O75643-2 O75643 SNRNP200 U5 small nuclear ribonucleoprotein 200 kDa helicase 1 EEAS(1)DDDMEGDEAVVR;EEAS(1)DDDMEGDEAVVR 132.23 5.68e-05 0.0 14237.7 20254.5 29647.0 16286.3 20911.9 15321.7 19454.8 13477.9 16146.8 13947.3 True False 16647.861402606864 22265.232902672797 30353.89691687361 15373.831411897005 16814.363312330206 14518.203079688683 17611.90050344538 13124.119406015461 16382.916403255547 16475.835083233946 1.0104411289930897 1.351387215894764 1.8423282803893921 0.9331139413711201 1.0205469542142207 0.8811816218324874 1.0689534348014633 0.7965677818279913 0.9943603052889893 1.0 14.008063970118602 -5.829363426256476 24.999952748347766 0.952140747262695 1.396395937048269 0.5084420787583515 0.20045978548919632 40.26613873794123 14819.647780369152 0.05659053586154945 0.08393736983967372 1.481278003473871e-06 5.829363426256476 0.444255189785574 EEAS(ph)DDDMEGDEAVVR ddPTM_PC-9_Lapatinib_30min_R1 3 EEASDDDMEGDEAVVR 16 0 O75643;A0A494C1A5;O75643-2 O75643 SNRNP200 U5 small nuclear ribonucleoprotein 200 kDa helicase 1 EEAS(1)DDDMEGDEAVVR;EEAS(1)DDDMEGDEAVVR;EEAS(1)DDDMEGDEAVVR 246.38 5.281e-47 15018400.0 30238.1 28717.300000000003 26693.4 23818.800000000003 26517.899999999998 22659.300000000003 25235.5 21405.8 26339.199999999997 21935.5 True False 29806.8991490116 28650.80685623564 24498.77169150379 25570.514009187533 24958.169258197304 21690.214560408185 26542.070711750188 22400.391613714855 23372.6019319279 25727.02194778351 1.1585833451500431 1.1136464575801408 0.952258358593831 0.9939165932647148 0.9701149751748688 0.8430907628730377 1.0316806494595812 0.8706950870248215 0.9084845490226492 1.0 14.650996845955694 -5.0512685179549734 1.1605135556181347 0.9340375676816438 1.224362577130564 0.6396327633438739 0.05679511283264925 0.6257422029043588 0.976766849837192 0.017489838572535315 0.19722186583569884 8.886515076787523e-06 5.0512685179549734 0.29032500944892015 EEAS(ph)SPGAGEGPAEEGTR ddPTM_PC-9_Lapatinib_30min_R1 1 EEASSPGAGEGPAEEGTR 18 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 EEAS(0.5)S(0.5)PGAGEGPAEEGTR 221.78 2.6545e-28 1643300.0 6355.7 7493.0 8885.5 6270.2 8288.1 9756.7 8408.2 7732.5 8443.0 7266.1 True False 6265.066552507368 7475.650418868552 8154.968489021883 6731.331424774033 7800.610253031547 9339.428684978555 8843.535454361428 8091.780178879092 7492.060431268504 8522.035703530342 0.7351607961360687 0.8772141632511216 0.95692728506683 0.7898736474414803 0.9153458779573127 1.0959152261131222 1.037725698649432 0.9495125883510425 0.8791397609569788 1.0 13.056982380439926 -6.526306316738661 24.95549901184052 0.9936321943959003 0.8510555333916817 0.4758428302636526 0.07521274932226005 98.85236270902261 719715.3284296253 0.025864305825179925 0.02598577038914317 2.976416361857575e-07 6.526306316738661 -0.14257666100421862 EEAS(ph)SPLK ddPTM_PC-9_Lapatinib_30min_R1 1 EEASSPLK 8 0 D6RA28;A0A590UJ84;B1AKN3;Q9P2R6-2;Q9P2R6 D6RA28 RERE Arginine-glutamic acid dipeptide repeats protein 1 EEAS(0.5)S(0.5)PLK 79.97399999999999 0.019955 7347000.0 59490.0 110660.0 95118.0 98634.0 117410.0 111110.0 120900.0 113480.0 88788.0 105350.0 True False 58641.661690870125 110403.7735689304 87297.76520609819 105887.8733933787 110504.17463694148 106358.08431006043 127159.6104317568 118752.69507910738 78787.76046091046 123559.60712994865 0.4746022025563436 0.8935264212423227 0.7065234928619223 0.8569780679378136 0.8943389931688868 0.8607836070424112 1.0291357619648467 0.9610964119869222 0.6376498136486363 1.0 16.914847663330022 -4.487502440018776 2.2165098998056547 0.8737044711389925 6.494873704228097e-26 0.49977159959479733 0.11710002521534743 1.9682636686723103 4.845897091330615 0.03069299903212221 4.658550617700325 3.254599549446912e-05 4.487502440018776 -0.8737044711389925 EEASDYLELDTIK ddPTM_PC-9_Lapatinib_30min_R1 2 EEASDYLELDTIK 13 0 P14625;Q96GW1;A0A1W2PRR1 P14625 HSP90B1 Endoplasmin 0 ; 184.03 0.00021347 10655600.0 62339.0 66428.0 69810.0 60559.0 55471.0 53825.0 53902.0 50448.0 59435.0 58307.0 False True 61450.034428427534 66274.19004732427 64070.49127439294 65012.71087890188 52208.304840182056 51523.0302222033 56692.78181548846 52791.998249478514 52740.80442170358 68385.28726080612 0.8985856006434676 0.969129365422849 0.9369046156089464 0.9506827196756229 0.7634435261063 0.7534227358833201 0.8290201604224449 0.7719788914264804 0.7712302826273436 1.0 16.06139834970389 -6.254304666962921 24.55199948586629 0.8010854280500536 0.9408529303940438 0.42436808647798974 0.06962242708517354 359.86555756233423 1238369.387999508 0.01935810846192215 0.024441445343616742 5.567950081624296e-07 6.254304666962921 0.13976750234399027 EEASGSSVTAEEAK ddPTM_PC-9_Lapatinib_30min_R1 1 EEASGSSVTAEEAK 14 0 P13010 P13010 XRCC5 X-ray repair cross-complementing protein 5 0 167.44 0.0018178 3401500.0 9024.0 11784.0 11785.0 11125.0 9829.8 8652.4 12209.0 10379.0 10390.0 10967.0 False True 8895.316105201076 11756.714872006796 10816.082791415552 11943.169611912079 9251.630490130365 8282.357021729526 12841.1222809042 10861.246230402343 9219.768788449566 12862.631337391073 0.6915627037636386 0.914020977794067 0.8408919223218115 0.9285168251066824 0.7192642195408574 0.6439084511155271 0.9983277872215502 0.8444031353700704 0.716787144606106 1.0 13.650898187773487 -10.950539273485374 4.529730094896697 1.000467306403356 0.8171289064408102 0.20786172217241283 0.11016129279734803 0.0005230294680341717 6.608551504420709e-05 0.10730896789771967 0.025960531562706498 1.1206260827304378e-11 10.950539273485374 -0.18333839996254586 EEASLLSHS(ph)PGTSNQSQPCSPKPIR ddPTM_PC-9_AZD4547_30min_R2 1 EEASLLSHSPGTSNQSQPCSPKPIR 25 1 Q9H4Z3 Q9H4Z3 PCIF1 Phosphorylated CTD-interacting factor 1 1 EEASLLS(0.042)HS(0.495)PGT(0.1)S(0.1)NQS(0.003)QPCS(0.26)PKPIR 77.1 6.4155e-05 8394300.0 2625.5 2028.2 19944.0 30397.0 18905.0 20426.0 10428.0 24984.0 15658.0 21829.0 True False 3460.3543862074707 2683.7759863872916 19679.529528821902 23389.44127896848 16280.367074053553 19148.7589909971 11356.071798287212 21123.296875205368 16485.649913559442 21064.773354230496 0.1642720919906085 0.12740588000906744 0.9342388450084894 1.1103580791326726 0.7728716943818397 0.9090417764761471 0.5391024915065863 1.0027782649255572 0.7826170088010268 1.0 14.362544772900993 -5.259469861826045 24.999995694706154 0.8745420386586512 0.1458389080038265 0.793964858173308 0.14984449449651915 70.14717009526873 890393.8816159719 0.038863448522253784 0.09275727230260637 5.5021210154537995e-06 5.259469861826045 -0.7287031306548247 EEASLLSHS(ph)PGTSNQSQPCSPKPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEASLLSHSPGTSNQSQPCSPKPIR 25 1 Q9H4Z3 Q9H4Z3 PCIF1 Phosphorylated CTD-interacting factor 1 1 EEASLLS(0.001)HS(0.692)PGT(0.152)S(0.152)NQS(0.002)QPCS(0.002)PKPIR 89.65899999999999 2.7655e-06 9502300.0 33867.0 44398.0 95382.0 111380.0 140520.0 139560.0 114830.0 86245.0 100400.0 82929.0 True False 39600.01419625973 48805.54002383999 97656.2686182495 105139.73969883214 112986.11473126026 132241.2279186611 103952.47110279388 83981.1601341308 101868.16006186118 97963.37123439723 0.40423286476645104 0.49820192393198515 0.9968651281363835 1.0732556298748028 1.1533506177622048 1.349904829247323 1.0611361143755098 0.8572710297320092 1.039859682024631 1.0 16.579954802077907 -5.261946868804127 2.971837819227389 1.083351001690817 0.4113475123890319 0.8180735876950624 0.11694477914954765 0.11269469077695758 1.991661728657802 0.03550904314060693 0.10556819889389742 5.470828884280544e-06 5.261946868804127 -0.6720034893017851 down EEASLLSHSPGTSNQSQPCS(ph)PKPIR ddPTM_PC-9_AZD4547_30min_R2 2 EEASLLSHSPGTSNQSQPCSPKPIR 25 1 Q9H4Z3 Q9H4Z3 PCIF1 Phosphorylated CTD-interacting factor 1 1 EEASLLSHS(0.153)PGT(0.153)S(0.153)NQS(0.043)QPCS(0.498)PKPIR;EEASLLS(0.002)HS(0.257)PGT(0.007)S(0.007)NQS(0.019)QPCS(0.708)PKPIR 82.8 1.3519e-05 26891200.0 15674.5 27217.8 84264.0 143648.0 125934.0 111647.0 67513.9 123935.0 84312.0 93358.0 True False 20658.664950146256 36015.42157691157 83146.60430288057 110532.1729394764 108450.23787907213 104665.69544051 73522.50630824549 104783.6934929787 88768.5601936406 90089.5648359635 0.22931251791216753 0.39977351031153296 0.9229326887556314 1.2269142729319997 1.2038046590250495 1.1617959930330106 0.8161045781730263 1.1631057790518857 0.98533676297884 1.0 16.459072386461997 -5.263708831480688 2.762263220303045 1.084625982532687 0.2551140380594569 0.8679544711684 0.11834373084353059 0.09123063855289602 1.3622504214318654 0.03330666450479379 0.10307980761614105 5.448678317617031e-06 5.263708831480688 -0.82951194447323 down EEASLLSHSPGTSNQSQPCS(ph)PKPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEASLLSHSPGTSNQSQPCSPKPIR 25 1 Q9H4Z3 Q9H4Z3 PCIF1 Phosphorylated CTD-interacting factor 1 1 EEASLLSHS(0.054)PGT(0.001)S(0.001)NQS(0.009)QPCS(0.934)PKPIR 85.15700000000001 4.3866000000000005e-06 13399000.0 23322.0 36577.0 68041.0 84177.0 98003.0 98135.0 90621.0 65933.0 87327.0 57691.0 True False 27269.95396950333 40208.12283102834 69663.35548692955 79460.83559551618 78800.01567042191 92988.62784320599 82036.72284077594 64202.328611788056 88603.99216854715 68149.92161829524 0.40014651993645955 0.5899951441798026 1.0222074190651456 1.1659710489554616 1.156274487178098 1.364471530342049 1.2037684107732372 0.9420748709203588 1.3001334420428872 1.0 16.056424377284824 -5.221297843729708 1.9701843881962158 1.171303429415776 0.38437481815007407 0.8371266374460535 0.11739005441457191 0.14402274699369866 0.982976327731235 0.03324725635450252 0.1462342696095733 6.007615875470471e-06 5.221297843729708 -0.7869286112657019 down EEASLLSHSPGTSNQSQPCS(ph)PKPIR ddPTM_PC-9_Lapatinib_30min_R1 3 EEASLLSHSPGTSNQSQPCSPKPIR 25 1 Q9H4Z3 Q9H4Z3 PCIF1 Phosphorylated CTD-interacting factor 1 1 EEASLLSHS(0.011)PGT(0.001)S(0.001)NQS(0.007)QPCS(0.98)PKPIR;EEASLLSHS(0.023)PGT(0.001)S(0.001)NQS(0.003)QPCS(0.972)PKPIR;EEASLLS(0.002)HS(0.127)PGT(0.01)S(0.007)NQS(0.007)QPCS(0.846)PKPIR 88.0 3.3631e-06 32175400.0 85453.8 57428.6 153580.0 86842.1 140353.0 206778.0 123811.0 121288.7 206412.0 100624.7 True False 84235.21314169251 57295.627605102636 140953.24523594385 93228.75773075309 132097.71248461498 197934.58696306098 130221.32776812435 126924.21578816828 183163.70694527955 118017.54532101535 0.7137516113605591 0.4854839799392101 1.194341441796149 0.7899567600492354 1.1193057110728803 1.677162378057145 1.1034065097178045 1.0754690367684416 1.5520040384424403 1.0 16.848641831193042 -5.606933927331732 0.9565271337557888 1.2698252886348451 0.5558370299529074 0.4543314329759194 0.2528768173159213 0.6958614783644336 1.0888951189622194 0.09854791704319604 0.39552545629371044 2.4721002166449495e-06 5.606933927331732 -0.7139882586819377 EEAT(ph)SPGAK ddPTM_PC-9_AZD4547_30min_R2 1 EEATSPGAK 9 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 EEAT(0.62)S(0.38)PGAK 117.02 0.0046046 5693300.0 106750.0 91168.0 57766.0 45133.0 39814.0 47534.0 46199.0 60059.0 99724.0 122240.0 True False 140694.2794620634 120636.27311259079 56999.985096366145 34728.28414789895 34286.51333966508 44561.69146568373 50310.62150067806 50778.261568522204 104995.20704941891 117960.41480696012 1.192724522818157 1.0226843751779753 0.4832128234683261 0.2944062565796424 0.29066117981845246 0.3777681821364231 0.4265042775833774 0.4304686589278261 0.8900884862200721 1.0 16.847943275184875 -5.196540414216216 3.66543890869064 0.47636590835471665 1.1540609667200692 0.5030900038954053 0.2304116147944291 0.17040217782288183 4.5122289438846765 0.05907505798969399 0.17828995962829125 6.36003617385504e-06 5.196540414216216 0.6776950583653525 EEAT(ph)SPGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEATSPGAK 9 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 EEAT(0.5)S(0.5)PGAK 110.53 0.0056125 6362400.0 24818.0 47120.0 48790.0 25859.0 145990.0 142990.0 43369.0 64349.0 110070.0 174000.0 True False 29019.197222156494 51797.76219476872 49953.338637105415 24410.20406600913 117384.30749798397 135491.3526804912 39260.77435563065 62659.90693340131 111679.5655180182 205544.82261675768 0.14118184468340197 0.2520022715013681 0.24302893160312963 0.11875854499883186 0.5710886122237644 0.6591815398489382 0.19100833509600545 0.30484789709460075 0.5433343642337658 1.0 17.649093507349612 -14.52287874527038 0.135709371455032 3.2577050271335106 0.08311889807115541 0.6476099486829817 0.15953924486289345 99.00540882336928 0.8307537108681557 60.52225978415323 1.1699271489448233 3.0000000000687905e-15 14.52287874527038 -3.174586129062355 EEAT(ph)SPGAK ddPTM_PC-9_Lapatinib_30min_R1 1 EEATSPGAK 9 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 EEAT(0.643)S(0.357)PGAK 142.0 0.0016780999999999999 10770000.0 71913.0 130990.0 57655.0 115890.0 148710.0 57849.0 262620.0 226150.0 111720.0 116980.0 True False 70887.50743277092 130686.7007030013 52914.828454735994 124412.93719770706 139963.170175109 55374.93312260543 276217.178590471 236657.7546011653 99136.91713624504 137199.83713394776 0.5166734080271806 0.9525281037718164 0.3856770500614765 0.9068009102390049 1.0201409352874333 0.4036078633864781 2.0132471317790346 1.7249127954147432 0.722573140079299 1.0 17.06591924336601 -7.247322974818681 24.989227260994642 1.4255927055482127 0.7191559926151588 0.4055670759707365 0.3927262940905842 754.1733947410304 1335059.1790323826 0.14880805359549315 0.11470081795271683 5.658183464429167e-08 7.247322974818681 -0.7064367129330539 EEATS(ph)PGAK ddPTM_PC-9_Lapatinib_30min_R1 1 EEATSPGAK 9 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 EEAT(0.476)S(0.524)PGAK 143.4 0.00060673 10218000.0 46326.0 98853.0 40010.0 83519.0 109320.0 41097.0 193410.0 170380.0 79077.0 86847.0 True False 45665.38274485204 98624.11195201034 36720.532243066285 89661.26587121647 102890.01253138951 39339.37711178612 203423.82343760188 178296.47680277046 70170.51554227405 101858.38823364668 0.44832225933227055 0.9682473251567909 0.3605057264290823 0.8802541197250051 1.0101280249533937 0.38621637151324195 1.9971239184639415 1.7504348919579127 0.688902669275644 1.0 16.63620526833681 -7.248190750979994 24.96672973813554 1.421651643419517 0.699098030939015 0.40321920031416236 0.4039065525130071 734.0654153126388 1383330.9648859133 0.1527859533902208 0.11763482323904205 5.646888974734464e-08 7.248190750979994 -0.722553612480502 EEATYGVWAERDS(ph)DDERPSFGGK ddPTM_PC-9_AZD4547_30min_R2 2 EEATYGVWAERDSDDERPSFGGK 23 2 Q9UBB9;F6UKU9;F6SQZ1;F6XM96 Q9UBB9 TFIP11 Tuftelin-interacting protein 11 1 EEAT(0.001)Y(0.002)GVWAERDS(0.997)DDERPSFGGK;EEATYGVWAERDS(1)DDERPSFGGK 77.899 9.164e-05 15371400.0 40712.0 49303.0 57433.0 76417.0 63774.0 66431.0 58591.0 68342.0 53889.0 59100.0 True False 53657.569137794126 65239.23057728662 56671.40089394441 58800.24128088082 54920.08091937006 62277.05906838966 63805.48549419311 57781.31424292691 56737.462523426024 57030.92698863996 0.9408503766470817 1.1439272342580311 0.993695945100679 1.0310237687806352 0.9629876949099853 1.0919874944483137 1.118787452059171 1.013157549664876 0.9948542925617815 1.0 15.799456862214022 EEATYGVWAERDS(ph)DDERPSFGGK ddPTM_PC-9_Lapatinib_30min_R1 2 EEATYGVWAERDSDDERPSFGGK 23 2 Q9UBB9;F6UKU9;F6SQZ1;F6XM96 Q9UBB9 TFIP11 Tuftelin-interacting protein 11 1 EEAT(0.002)Y(0.002)GVWAERDS(0.989)DDERPS(0.006)FGGK;EEATYGVWAERDS(0.999)DDERPS(0.001)FGGK 67.655 0.00045841 13258700.0 25636.6 25874.0 28535.0 29171.0 32318.0 35712.0 27638.2 27086.5 33365.0 22517.0 True False 25271.01738282336 25814.09034269382 26188.96244828535 31316.332651603316 30417.11877963266 34184.68100873801 29069.170761248803 28345.037674129766 29607.082350973986 26409.033447983446 0.9569080758899572 0.977471984862246 0.9916668286958871 1.1858189627911044 1.1517694821941795 1.2944313572122912 1.1007283102013141 1.0733084090320675 1.1210967796034481 1.0 14.6887438803987 -5.7007617466479426 6.569026607056276 1.141607873273578 0.9731000565999747 0.4933686006113286 0.07261417983169265 0.17056161935894495 14.159134174882647 0.02033582959894749 0.03523254555777106 1.991765719239213e-06 5.7007617466479426 -0.16850781667360326 EECPRPMSIS(ph)PPDFSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EECPRPMSISPPDFSPK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 EECPRPMS(0.035)IS(0.915)PPDFS(0.05)PK 73.796 0.01818 0.0 29364.0 28391.0 28153.0 25133.0 19572.0 19565.0 23042.0 16902.0 19807.0 18544.0 True False 34334.745234563765 31209.47085041763 28824.274290847065 23724.879492285392 15737.007098777593 18538.976957785937 20859.294950366428 16458.340409149303 20096.639903837466 21905.88040577677 1.5673757273644842 1.4247074425818294 1.3158235942548948 1.0830370226082735 0.7183919024148241 0.8463013864029427 0.9522235383365669 0.7513206547411395 0.9174084552446387 1.0 14.41903057784527 -5.76138731588573 1.847397102273973 0.8547505331773355 1.4954368514396195 0.8901692550496554 0.09073282684390788 0.09952290326335321 0.6922931400801735 0.027704363731909924 0.05664938335651619 1.7322584324670825e-06 5.76138731588573 0.640686318262284 EECPRPMSISPPDFS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EECPRPMSISPPDFSPK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 EECPRPMS(0.039)IS(0.347)PPDFS(0.614)PK 82.837 0.0063921 6365300.0 39422.0 49786.0 33460.0 41262.0 39127.0 26036.0 38032.0 30732.0 29893.0 31647.0 True False 46095.36598000857 54728.42505578848 34257.81329775664 38950.22391320894 31460.34522551965 24670.626326241483 34429.33363216456 29925.31756324556 30330.128573000107 37384.35058248582 1.233012350403213 1.4639394346314571 0.9163677518529925 1.0418857973008822 0.8415378289400725 0.6599185472490036 0.9209557768349825 0.8004771273802803 0.8113054821182171 1.0 15.190146851215381 -5.452002746930182 1.7618486576615426 0.840054423477982 1.3634561671973628 0.6826847006568046 0.124828824573174 0.20535841289326304 1.1985262072538247 0.035727127015498544 0.11318823466611767 3.5318093590117293e-06 5.452002746930182 0.5234017437193809 EEDEEPES(ph)PPEK ddPTM_PC-9_AZD4547_30min_R2 1 EEDEEPESPPEK 12 0 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 EEDEEPES(1)PPEK 189.99 0.00018472 24057000.0 30908.0 49567.0 34255.0 29038.0 27867.0 49796.0 51205.0 44777.0 48096.0 39358.0 True False 40736.10107366235 65588.56341448518 33800.75631818059 22343.737732627804 23998.148069434046 46682.24824810005 55762.14580277103 37857.74352309764 50638.256370069925 37980.08839964287 1.0725646724415048 1.726919714465486 0.8899599169573924 0.5883013619535942 0.631861301030034 1.2291242652436536 1.468194207870653 0.9967787100636033 1.3332843209113248 1.0 15.212955642950972 EEDEEPES(ph)PPEK ddPTM_PC-9_Lapatinib_30min_R1 1 EEDEEPESPPEK 12 0 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 EEDEEPES(1)PPEK 161.87 4.3404e-12 0.0 15199.0 22515.0 16576.0 12980.0 16837.0 19349.0 22125.0 25182.0 16348.0 18023.0 True False 14982.259472844764 22462.867900817477 15213.185265210383 13934.592500010667 15846.680762815626 18521.488374722005 23270.52424154356 26352.04765141071 14506.716087928158 21138.251535862062 0.7087747748401346 1.0626644243828842 0.7196993204192164 0.6592121621965733 0.7496684735693947 0.8762072086851369 1.1008727094605717 1.2466521938535546 0.6862779574420721 1.0 14.36756842775239 -7.052125908497077 4.470560521260302 1.027287000802496 0.7870273274978231 0.2927773884771143 0.16592085141181556 0.2739305763176189 11.561045893592073 0.06463927688868418 0.05097530988283058 8.868988494569406e-08 7.052125908497077 -0.2402596733046728 EEDEEPES(ph)PPEKK ddPTM_PC-9_AZD4547_30min_R2 7 EEDEEPESPPEKK 13 1 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 EEDEEPES(1)PPEKK;EEDEEPES(1)PPEKK;EEDEEPES(1)PPEKK;EEDEEPES(1)PPEKK;EEDEEPES(1)PPEKK;EEDEEPES(1)PPEKK;EEDEEPES(1)PPEKK 158.31 0.00035916 616255000.0 349533.0 435939.0 322138.0 263424.0 322593.0 425749.0 455583.0 408456.0 417525.0 347489.0 True False 460677.22326195164 576847.7564982194 317866.23963877035 202695.6666602293 277806.53031050775 399126.8477263306 496129.00441878394 345338.5105851299 439594.5191058188 335323.5158774193 1.3738291573632329 1.720272301776448 0.9479390039408073 0.6044779356731027 0.8284731525124011 1.190273955830271 1.4795532699834526 1.0298666637843903 1.3109564295112448 1.0 18.35519413576744 -6.981178088184694 24.899108898401337 1.2257731841784187 1.0858205703763852 0.02700284318069124 0.3103902559934565 1000.3006543657273 1323271.7008239713 0.12338811746857113 0.10880175265988111 1.0442919057291195e-07 6.981178088184694 -0.1399526138020335 EEDEEPES(ph)PPEKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EEDEEPESPPEKK 13 1 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 EEDEEPES(1)PPEKK;EEDEEPES(1)PPEKK;EEDEEPES(1)PPEKK;EEDEEPES(1)PPEKK 144.88 0.00013877 52949100.0 139330.0 208862.7 130170.0 134218.0 153545.0 106002.0 148317.0 92921.0 109223.0 114181.4 True False 162915.81710706203 229597.20853050353 133273.74647247416 126698.20060062736 123458.95948200484 100443.06851414402 134267.34003790878 90481.92220793782 110820.17974538504 134881.5839605346 1.2078432972341877 1.7022131694248346 0.9880796366646252 0.9393291276717092 0.9153136837281513 0.7446759265781825 0.9954460504941465 0.6708248787648594 0.8216109011428147 1.0 17.041333857989812 -5.414852997707719 5.03265997336278 0.8645245050504782 1.4502572594790855 0.7050598327322766 0.14899372517386925 0.1058072088065987 4.00468546508068 0.03761239057772683 0.08043633587215955 3.8472198273928295e-06 5.414852997707719 0.5857327544286073 EEDEEPES(ph)PPEKK ddPTM_PC-9_Lapatinib_30min_R1 6 EEDEEPESPPEKK 13 1 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 EEDEEPES(1)PPEKK;EEDEEPES(1)PPEKK;EEDEEPES(1)PPEKK;EEDEEPES(1)PPEKK;EEDEEPES(1)PPEKK;EEDEEPES(1)PPEKK 214.89 3.2828e-14 855901200.0 647226.0 707590.0 461154.0 480384.0 616676.0 522894.0 587427.0 631928.0 507708.0 523046.0 True False 637996.4385532876 705951.6188291991 423239.69822591887 515713.0418740457 580404.3301116638 500531.042545449 617841.095757614 661289.681846582 450524.5786377438 613453.8041850126 1.0400073065010667 1.150782037723398 0.6899292095648547 0.8406713567604039 0.9461255699322694 0.8159229580626954 1.007151788028163 1.0779779623750487 0.7344066913665586 1.0 19.226595181026674 -5.22870176169135 24.980254528191843 0.8937287473626245 1.0953947227735263 0.3225100072110688 0.11948796160975034 779.8007467416136 595020.2705853725 0.030477802398756117 0.08062499931156188 5.90606521713082e-06 5.22870176169135 0.2016659754109018 EEDEHPY(ph)ELLLTAETK ddPTM_PC-9_AZD4547_30min_R2 1 EEDEHPYELLLTAETK 16 0 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 EEDEHPY(1)ELLLTAETK 146.78 5.2095e-05 851990.0 9200.3 8919.0 9116.0 12522.0 8974.0 11069.0 7084.5 8691.5 10044.0 9982.1 True False 12125.804021871867 11801.892329448894 8995.115883711409 9635.246362971464 7728.115002515557 10376.853680179516 7715.006775504965 7348.428385800812 10574.905334767594 9632.629717314769 1.2588259258087735 1.2251994186213604 0.9338172594283967 1.000271643957412 0.8022850695303045 1.0772607257524907 0.8009242545301152 0.7628683548991739 1.0978212227715007 1.0 13.23371399365661 -5.248807781458537 3.998141500552826 0.9220075575424748 1.2535451748652267 0.5532784383570495 0.11031423525788406 0.14410852709418145 5.44309691847603 0.02829152165520195 0.07596007051075016 5.638871768126189e-06 5.248807781458537 0.3315376173227519 EEDEHPY(ph)ELLLTAETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEDEHPYELLLTAETK 16 0 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 EEDEHPY(1)ELLLTAETK 100.23 0.00314 873680.0 18900.0 17154.0 25340.0 16478.0 27484.0 20487.0 21472.0 16855.0 22488.0 17584.0 True False 22099.39670798443 18856.93575316347 25944.20170248514 15554.791082396796 22098.707495544804 19412.62565469771 19438.016716182086 16412.574109348683 22816.844456883766 20771.840005132595 1.063911367626739 0.9078124878924562 1.2490083543910644 0.7488403087330396 1.0638781874925065 0.9345645667355885 0.9357869457582512 0.790135785048086 1.0984508089435439 1.0 14.34234139778803 -5.763113440515538 24.99990402038397 0.934972331583437 1.0570008673066555 0.18646309426516106 0.12742292500275537 78.15078440485446 1167111.963571361 0.03347969272415325 0.05272114859754191 1.7253871508891866e-06 5.763113440515538 0.12202853572321859 EEDEPEER ddPTM_PC-9_AZD4547_30min_R2 2 EEDEPEER 8 0 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 0 ; 126.52 0.01627 10730800.0 16346.3 15198.400000000001 21919.0 26531.0 24942.0 26323.0 19278.1 24520.0 20743.3 20853.3 False True 21544.083375838196 20110.985579089163 21628.339738379826 20414.687849863894 21479.23383025885 24677.01864878178 20993.813553371743 20730.99741354609 21839.748489713733 20123.23231425053 1.07060749681757 0.9993914131204114 1.074794516140602 1.0144835348050405 1.0673848760891187 1.2262949740587366 1.043262495086572 1.030202160855896 1.0853002215875442 1.0 14.29657443763527 -3.914109490021264 10.871207429663295 1.0636383065001263 1.0826172432018841 0.0 0.06264210715129553 107967.73351086894 6478.849941789774 0.015116311436859172 221197.23012714225 0.0001218682318082333 3.914109490021264 0.018978936701757876 EEDEPEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EEDEPEER 8 0 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 0 ; 143.89 0.0077832 13356500.0 26175.9 31127.2 31741.8 33432.0 38919.0 30134.0 33071.1 26755.0 31907.1 23961.8 False True 30606.96287240898 34217.30270350178 32498.644893446846 31558.913428006417 31293.10133237914 28553.719992124807 29938.36599397025 26052.709599265752 32373.68097519726 28305.88465849558 1.0812932802374988 1.2088406038647508 1.148123271381058 1.1149241159129253 1.1055334150450937 1.0087556116552903 1.0576728604376866 0.9203990588383334 1.143708503223933 1.0 14.788814393210021 -6.5175526306666445 1.7661251439296546 1.0214182349946193 1.148219617295106 0.43252675325137024 0.06055021134266088 0.3090144216048492 1.9486586911992356 0.02190267100325212 0.023988232609376513 3.037018023790729e-07 6.5175526306666445 0.12680138230048676 EEDEPEER ddPTM_PC-9_Lapatinib_30min_R1 2 EEDEPEER 8 0 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 0 ; 117.04 0.016422 12856900.0 59765.0 49985.0 49106.0 43590.0 54616.0 52525.0 42964.0 51535.0 52814.0 40461.0 False True 58912.74014044128 49869.26280356925 45068.69423464171 46795.75401197727 51403.59425918735 50278.6281917553 45188.46569553348 53929.504237767076 46865.53116392449 47454.62993910638 1.2414539996632132 1.050882977436792 0.9497217509118437 0.9861156661009773 1.0832155750692456 1.0595094357762913 0.9522456660924163 1.1364434683606053 0.9875860632368682 1.0 15.534261231059874 -4.772752742726052 4.381550473408241 1.0229876660832102 1.2586065607713117 0.5820020354218846 0.05603976814225686 0.14391998726127422 5.862213591951955 0.013935593977439998 0.10607765795336799 1.6875135055523036e-05 4.772752742726052 0.2356188946881015 EEDEPEERS(ph)GDETPGSEVPGDK ddPTM_PC-9_AZD4547_30min_R2 1 EEDEPEERSGDETPGSEVPGDK 22 1 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 EEDEPEERS(0.996)GDET(0.003)PGSEVPGDK 100.39 4.4674e-05 386990000.0 49240.0 61031.0 59368.0 42145.0 58100.0 68020.0 58313.0 73678.0 67031.0 54382.0 True False 64897.29574437471 80758.07722374664 58580.74152963792 32429.12138375914 50033.817879000904 63766.69864719591 63502.74403275051 62292.75805200855 70574.12181350126 52478.10273259256 1.2366547638939118 1.5388909472443684 1.1162892421652888 0.6179552936394248 0.9534227663289057 1.2151105952157897 1.2100807903886144 1.1870238215247138 1.3448299031144244 1.0 15.679427941964313 -5.369347091442977 6.874440791702264 1.0736384705657944 1.3854310001952856 0.2756932711164669 0.19970757515014723 0.3245126709111199 17.856833774108534 0.05747854570595588 0.12079974412751299 4.272213111638176e-06 5.369347091442977 0.3117925296294912 EEDEPEERS(ph)GDETPGSEVPGDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEDEPEERSGDETPGSEVPGDK 22 1 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 EEDEPEERS(0.997)GDET(0.001)PGS(0.002)EVPGDK 76.678 0.00036985 54125000.0 43146.0 41159.0 38044.0 39753.0 52257.0 30579.0 55557.0 33260.0 40756.0 30318.0 True False 50449.76562765587 45244.993509645275 38951.11324267346 37525.76829096491 42017.6159800133 28975.383408747075 50294.23876215205 32386.960241882956 41351.97939722321 35814.41340284403 1.4086441975243866 1.263318011123766 1.08758205263751 1.0477839709077847 1.173204081479572 0.8090425238249507 1.404301620033184 0.9042996147274912 1.154618363620593 1.0 15.128252692177906 -5.0208110229580685 2.0440104347267063 1.0718868571299036 1.4319925742434496 0.34441741938876835 0.151978699135515 0.48604526203492243 3.1843661287628504 0.038696581025418134 0.2733921105515999 9.532108498839548e-06 5.0208110229580685 0.360105717113546 EEDEPEERS(ph)GDETPGSEVPGDK ddPTM_PC-9_Lapatinib_30min_R1 3 EEDEPEERSGDETPGSEVPGDK 22 1 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 EEDEPEERS(1)GDETPGSEVPGDK;EEDEPEERS(0.861)GDET(0.112)PGS(0.027)EVPGDK;EEDEPEERS(0.759)GDET(0.104)PGS(0.137)EVPGDK 99.34299999999999 5.1612e-05 640973000.0 111167.0 143266.0 141332.0 129909.0 150053.0 142783.0 137545.0 160900.0 149012.0 125843.0 True False 109581.7381944688 142934.27637923646 129712.22851729687 139462.9412237202 141227.1775555487 136676.5039334295 144666.4070871461 168376.0013943284 132228.6993940759 147594.79487474295 0.7424498830562818 0.9684235578940188 0.8788401286602132 0.9449041976180537 0.9568574398263966 0.9260252304251021 0.9801592746540823 1.1407990474001575 0.8958899906076799 1.0 17.171282318187366 -3.060596232828014 0.41795433715454894 1.0030286711028107 1.7827351894915183e-13 0.44785176046400577 0.07105472093945686 20.794054090285396 0.9021572842135231 0.04923898651825117 14.069962533310774 0.0008697686846474316 3.060596232828014 -1.0030286711026324 EEDGADAS(ph)EEDLTR ddPTM_PC-9_AZD4547_30min_R2 1 EEDGADASEEDLTR 14 0 Q86X53;E5RHA3 Q86X53 ERICH1 Glutamate-rich protein 1 1 EEDGADAS(0.997)EEDLT(0.003)R 79.346 0.012882 2796400.0 6540.9 4312.1 7471.2 6850.1 8123.1 6514.4 6682.5 11261.0 6986.0 8367.2 True False 8620.7701408282 5705.9019972885535 7372.127006404639 5270.91527799 6995.347779912425 6107.053538184251 7277.229554282151 9520.871202036813 7355.265697798329 8074.2668747774715 1.0676845680885163 0.7066774093277428 0.9130397992458995 0.6528041938340399 0.8663755964971394 0.7563601293959661 0.9012867257354202 1.1791623127764415 0.9109515218991373 1.0 12.979115556959208 -7.5321970634131485 23.35006351073846 1.0350792287531554 0.8202236925063605 0.3468839477662774 0.12424994548034833 91.5326982384367 229356.90674178806 0.05408406473007588 0.03129645170229715 2.9363169803048e-08 7.5321970634131485 -0.21485553624679488 EEDGADAS(ph)EEDLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEDGADASEEDLTR 14 0 Q86X53;E5RHA3 Q86X53 ERICH1 Glutamate-rich protein 1 1 EEDGADAS(1)EEDLTR 182.37 1.8472000000000002e-05 3722800.0 9613.8 10275.0 12680.0 8508.5 8765.2 12162.0 11799.0 7845.4 9537.8 10043.0 True False 11241.226458794748 11295.034094890663 12982.339289167785 8031.7963299291905 7047.721981514683 11524.203310022633 10681.313302637507 7639.466562888412 9677.27228125516 11863.71639965575 0.947529937509374 0.9520654164675085 1.094289415881898 0.6770050850307118 0.5940568489751817 0.9713822314866724 0.9003345109419041 0.6439353660805721 0.8157032716608066 1.0 13.534268395460318 -5.759696361811392 24.999993965489818 0.7882067045300601 0.9933719712430199 0.31420862995322685 0.13289270645011075 55.25892316897649 792547.5765644143 0.03757699796123754 0.06099683488028964 1.7390162418370612e-06 5.759696361811392 0.20516526671295976 EEDGADAS(ph)EEDLTR ddPTM_PC-9_Lapatinib_30min_R1 2 EEDGADASEEDLTR 14 0 Q86X53;E5RHA3 Q86X53 ERICH1 Glutamate-rich protein 1 1 EEDGADAS(1)EEDLTR;EEDGADAS(1)EEDLTR 160.8 0.00042644 14309500.0 18165.2 16755.800000000003 19611.9 16972.5 18360.300000000003 14148.7 15420.8 16545.2 16902.5 12418.4 True False 17906.160916910296 16717.00297457329 17999.485286123283 18220.71426860023 17280.383251738644 13543.593083230611 16219.21356944611 17313.950393222167 14998.762458784295 14564.90389352213 1.2294046735779849 1.147759236640643 1.2358121562428375 1.2510013386840164 1.1864399091177145 0.9298786440502531 1.1135819149935997 1.1887445684363698 1.0297879456283352 1.0 13.8302085614399 -6.548809963483539 24.995640904964436 1.0669235015741199 1.213309078235527 0.5620335175813902 0.06938257876925794 186.51496610902925 179784.31057370704 0.023367498965842472 0.023368058725545933 2.8261163429590494e-07 6.548809963483539 0.14638557666140706 EEEADMS(ph)SPTQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEEADMSSPTQR 12 0 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 EEEADMS(0.366)S(0.366)PT(0.267)QR 104.24 0.0017028 6248600.0 10901.0 16800.0 12915.0 9105.0 17061.0 11002.0 18129.0 15868.0 12304.0 12011.0 True False 12746.323995435892 18467.792972667958 13222.942580410258 8594.876368808282 13718.019523413263 10425.035752085922 16411.68987740616 15451.481813535753 12483.922723118907 14188.499220976315 0.898356041531982 1.3016029873945458 0.93194793716177 0.6057636001488863 0.966840770807705 0.7347525337051519 1.1566896274091536 1.0890145302113587 0.8798621001904586 1.0 13.792434376914057 -9.742645026673424 15.484068421970061 1.00000000654984 0.9553265403682826 0.0054946648643102725 0.1894185172747927 0.0 0.0 0.19068591026802492 0.04624812643247753 1.8086518349753715e-10 9.742645026673424 -0.04467346618155743 EEEADMSS(ph)PTQR ddPTM_PC-9_AZD4547_30min_R2 2 EEEADMSSPTQR 12 0 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 EEEADMS(0.034)S(0.882)PT(0.084)QR;EEEADMS(0.035)S(0.917)PT(0.048)QR 118.76 0.00050201 12229700.0 25852.0 28826.0 29170.0 28622.0 29795.0 39681.0 30282.0 42204.0 36309.0 27574.0 True False 34072.398244995435 38143.440776846495 28783.186740660596 22023.640105491857 25658.4785491365 37199.74079710938 32977.03933599282 35682.34155143961 38228.21961370735 26608.642652872393 1.2805011773615342 1.4334981785599998 1.0817232248993904 0.827687469549087 0.9642911471986219 1.3980322590071568 1.2393356461733294 1.341005703182222 1.4366843176640063 1.0 14.699607297729377 -6.772381427196454 24.99219933661637 1.3015946834772174 1.1170006776893795 0.15669022580009007 0.18950150486417516 417.9825369324415 954688.2859940443 0.07247893591252233 0.06452432373576295 1.688956922267165e-07 6.772381427196454 -0.1845940057878379 EEEADMSS(ph)PTQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEEADMSSPTQR 12 0 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 EEEADMS(0.31)S(0.682)PT(0.007)QR 118.76 0.00050178 10048000.0 21598.0 36174.0 36910.0 29066.0 40093.0 28651.0 47212.0 25927.0 32725.0 29006.0 True False 25254.114820055427 39765.115654362526 37790.0743819545 27437.526253243435 32237.06446000867 27148.4911227971 42739.73757472003 25246.443721927226 33203.54121538251 34264.558188630326 0.7370331373026503 1.1605319827984064 1.102891044849194 0.800755290705828 0.9408282541552099 0.792319894315915 1.2473453572473594 0.7368092587957111 0.9690345643038268 1.0 15.06442946438373 -5.74679958998296 24.99461361388134 0.9241074997537048 1.0161899883426952 0.035360813733810614 0.16925869651658304 768.2679797298429 1311658.39629325 0.04435340748401083 0.07640604117823255 1.791432339694932e-06 5.74679958998296 0.09208248858899049 EEEADMSS(ph)PTQR ddPTM_PC-9_Lapatinib_30min_R1 1 EEEADMSSPTQR 12 0 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 EEEADMS(0.11)S(0.575)PT(0.314)QR 83.53 0.0096177 2552600.0 5889.5 8292.1 7234.2 8191.0 15198.0 12553.0 16712.0 13953.0 13036.0 13175.0 True False 5805.514649997974 8272.900151915106 6639.432000819554 8793.393464374987 14304.083520417638 12016.137452472236 17577.26558755598 14601.307317930812 11567.748404834323 15452.281195416 0.37570599295851603 0.53538374349344 0.42967325774457016 0.5690676575950219 0.925693969681384 0.7776287074064434 1.1375191381302565 0.944928915884754 0.7486110470385405 1.0 13.915532216149932 -6.176858284555506 2.6426937425273977 0.9293639515718239 0.45467738901677035 0.8019436521939997 0.10932774222853411 0.12355540918671694 1.6882437848350766 0.035068317432996814 0.04689096326808173 6.654902781521706e-07 6.176858284555506 -0.4746865625550536 EEEAIQLDGLNASQIR ddPTM_PC-9_Lapatinib_30min_R1 2 EEEAIQLDGLNASQIR 16 0 P14625;Q96GW1;A0A1W2PRR1 P14625 HSP90B1 Endoplasmin 0 ; 150.12 0.00010458 7085900.0 31094.0 29307.0 31502.0 30958.0 28034.0 26799.0 29373.0 27716.0 28543.0 26832.0 False True 30650.59385805876 29239.141442116717 28912.02716123655 33234.7545928606 26385.095236964593 25652.869241520213 30893.790216807214 29003.786542232494 25328.186768885076 31469.875448607378 0.9739661635494375 0.9291152578556082 0.9187207368663413 1.0560815420809466 0.8384238850914232 0.8151563638506685 0.981694073345128 0.9216365215552826 0.8048391170231312 1.0 14.94168384830234 -6.283848911251735 24.99702010366314 0.8901868466623475 0.9629633873079274 0.21713858239727923 0.06993565944150844 1330.1984912484536 1483783.8788559444 0.021772033502551177 0.024702788188451393 5.201769318558523e-07 6.283848911251735 0.07277654064557992 EEEEEEEEDQEGDRETTIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEEEEEEEDQEGDRETTIR 19 1 A0A0B4J2E5;Q15269 A0A0B4J2E5 PWP2 Periodic tryptophan protein 2 homolog 0 81.428 0.017669999999999998 0.0 1180.5 2842.0 784.81 2262.0 1494.3 1199.1 1521.6 1509.2 875.41 1233.4 False True 1380.3353340622025 3124.1349778763292 803.522846808499 2135.267473502945 1201.502641922305 1136.2170851050914 1377.4630325699818 1469.585099129579 888.2112151369895 1457.0056564109714 0.9473781573795463 2.1442160942408295 0.5514891745772693 1.46551762795673 0.8246382823811099 0.7798302498728279 0.9454067844616841 1.0086337638177703 0.6096141159293177 1.0 10.508790762929452 -5.275089850330612 24.998804334280297 0.9135506069361202 1.5457972125476331 0.34198753347851596 0.3588398021345242 719.7787534619025 1318167.706124934 0.08698824886184763 0.18265875739671647 5.307746219540217e-06 5.275089850330612 0.6322466056115129 EEEEEEEEDQEGDRETTIR ddPTM_PC-9_Lapatinib_30min_R1 2 EEEEEEEEDQEGDRETTIR 19 1 A0A0B4J2E5;Q15269 A0A0B4J2E5 PWP2 Periodic tryptophan protein 2 homolog 0 ; 166.92 1.0260999999999999e-07 6493600.0 25325.7 24742.1 20360.3 15479.6 23936.6 19158.6 20364.0 18106.3 17781.6 15743.0 False True 24964.550873835433 24684.811187600084 18686.354727030815 16618.02142243183 22528.69624916625 18339.231338877922 21418.348278182737 18947.584798297907 15778.848959450896 18464.156573771077 1.3520547648138108 1.3369043470236623 1.0120340267031411 0.9000151919226171 1.2201313479527671 0.993234175934653 1.1599960275796286 1.0261819825127325 0.8545664621294023 1.0 14.172439742573413 -5.258565831437954 23.037812104366843 1.028501285904426 1.3444796835024002 0.6182673732684778 0.10159840547035734 52.86097905810551 423776.65533080156 0.026161021250911205 0.0630143712632816 5.513586197358859e-06 5.258565831437954 0.3159783975979742 EEEMGEEEEVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEEMGEEEEVER 12 0 Q14839-2;A0A2R8Y8C1;A0A0C4DGG9;A0A2R8Y521;A0A2R8Y212;F5GWX5;A0A2U3TZM0;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8YER1;Q14839;A0A2R8YDJ9;A0A2R8YE38;A0A2R8YDW2;A0A2R8Y5M9;A0A2R8Y5Z7 Q14839-2 CHD4 Chromodomain-helicase-DNA-binding protein 4 0 99.788 0.011909000000000001 0.0 4954.8 6118.2 4318.3 5357.0 6232.7 3507.8 3608.6 3191.0 4694.5 2861.6 False True 5793.54977823922 6725.574462224826 4421.26464924395 5056.864657628332 5011.447176811314 3323.844792871022 3266.7672839984475 3107.2396311439734 4763.14818137855 3380.3854275868644 1.713872545704064 1.9895880532847912 1.3079173200672953 1.4959432188885768 1.482507626471697 0.9832739088701478 0.9663889973429672 0.9191968483197847 1.4090547611840791 1.0 11.722972034946661 -5.8693501688010485 0.7388249063251779 1.0404474491104916 1.9017868247494738 0.6519275604799502 0.20179742789500274 0.5732033342832051 0.5771606637164751 0.10635713359258687 0.3260824693554938 1.3509828353066075e-06 5.8693501688010485 0.8613393756389822 EEENS(ph)EEELAAATTSK ddPTM_PC-9_AZD4547_30min_R2 3 EEENSEEELAAATTSK 16 0 P10244-2;P10244 P10244-2 MYBL2 Myb-related protein B 1 EEENS(1)EEELAAATTSK;EEENS(0.667)EEELAAAT(0.286)T(0.041)S(0.006)K;EEENS(1)EEELAAATTSK 196.31 4.440099999999999e-50 4511400.0 31379.2 40519.5 39659.5 23238.6 33785.6 46932.4 44203.4 53822.0 38619.9 36109.5 True False 41357.13287209348 53616.63597299077 39133.589116943025 17881.299802790978 29095.052621906572 43997.70960878644 48137.41696666752 45505.04660652034 40661.26906991153 34845.31739587639 1.1868777776433084 1.5387041926998142 1.1230659394588873 0.5131622019579325 0.8349774028848334 1.2626577370190106 1.381460137664412 1.3059156870215634 1.1669076968925358 1.0 15.088677175567316 -6.821774724432333 24.999082578663323 1.2523883010063903 1.0425150967189951 0.10472258584934824 0.26219384928011763 176.83974596061512 73269.14162872724 0.10462481531291906 0.09227045238129827 1.5073887703484216e-07 6.821774724432333 -0.2098732042873952 EEENS(ph)EEELAAATTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEENSEEELAAATTSK 16 0 P10244-2;P10244 P10244-2 MYBL2 Myb-related protein B 1 EEENS(1)EEELAAATTSK 199.41 2.8411999999999997e-50 0.0 12908.0 23108.0 13503.0 13402.0 17176.0 16029.0 18646.0 10106.0 14600.0 10679.0 True False 15093.069455379 25402.009524548284 13824.962730412662 12651.129389870242 13810.486098947667 15188.411022558194 16879.715894650308 9840.728208192098 14813.497379513647 12615.01816508251 1.1964366010312661 2.0136324174989517 1.095913026005717 1.0028625582868906 1.0947654548111654 1.203994383820917 1.3380651279101747 0.7800803835091215 1.1742747561407698 1.0 13.622854663283844 -5.338644303308591 12.607374201887122 1.0887373112678638 1.6048900557041146 0.44953126758567785 0.2296233995357594 0.8930718867845195 144.53900114521298 0.056491291982942095 0.11762598337300163 4.585172686547546e-06 5.338644303308591 0.5161527444362508 EEENS(ph)EEELAAATTSK ddPTM_PC-9_Lapatinib_30min_R1 4 EEENSEEELAAATTSK 16 0 P10244-2;P10244 P10244-2 MYBL2 Myb-related protein B 1 EEENS(1)EEELAAATTSK;EEENS(1)EEELAAATTSK;EEENS(1)EEELAAATTSK;EEENS(1)EEELAAATTSK 236.96 2.0217999999999998e-50 10908700.0 58477.0 78765.0 57490.0 57962.799999999996 74507.7 68405.3 65620.3 72662.0 62926.299999999996 60526.6 True False 57643.107256631556 78582.62448180735 52763.39411781758 62225.577670232524 70125.30357377429 65479.764779542704 69017.79805140616 76038.14178567244 55838.877450684704 70988.54216337494 0.8120057899480477 1.106976169491623 0.7432663428470822 0.8765580440717449 0.9878397476086498 0.9223990630607094 0.972238560591465 1.0711326006762645 0.7865900009916476 1.0 16.11529856616643 -6.253623112995597 23.92954847301925 0.9593185071926147 0.8904758215454907 0.09188641900961259 0.1101046008215758 913.6879761535013 2797256.6891943268 0.031742905743451295 0.04017432315965261 5.576694926167671e-07 6.253623112995597 -0.06884268564712404 EEEPTGWEEPS(ph)PESIR ddPTM_PC-9_Lapatinib_30min_R1 2 EEEPTGWEEPSPESIR 16 0 Q8NDV7-2;Q8NDV7-6;Q8NDV7-5;Q8NDV7;H7C269 Q8NDV7-2 TNRC6A Trinucleotide repeat-containing gene 6A protein 1 EEEPTGWEEPS(0.943)PES(0.057)IR;EEEPTGWEEPS(0.999)PES(0.001)IR 151.49 1.9309e-10 4307900.0 12492.2 15801.6 16182.3 14832.5 15231.8 12924.099999999999 18408.699999999997 17088.4 18721.1 16642.5 True False 12314.058937211092 15765.012366047418 14851.85375948442 15923.331529769508 14335.895470870986 12371.366370548578 19361.81241153912 17882.38944827125 16612.532576077305 19519.13395026267 0.6308711733107084 0.8076696643518484 0.760886922407977 0.815780637109426 0.7344534602508872 0.6338071351973122 0.9919401373480797 0.9161466637729901 0.8510896343253872 1.0 14.252601422543522 -7.269982759748117 24.984246452437493 0.9328063358235786 0.7395089836217772 0.681024261587071 0.06991984695944296 411.7903879593453 1204234.129412622 0.02916043241517515 0.02001808224782908 5.370531154235595e-08 7.269982759748117 -0.19329735220180144 EEEPTGWEEPS(ph)PESIRR ddPTM_PC-9_AZD4547_30min_R2 1 EEEPTGWEEPSPESIRR 17 1 Q8NDV7-2;Q8NDV7-6;Q8NDV7-5;Q8NDV7;H7C269 Q8NDV7-2 TNRC6A Trinucleotide repeat-containing gene 6A protein 1 EEEPTGWEEPS(0.984)PES(0.016)IRR 83.39299999999999 0.0017596 1942800.0 5230.6 4879.2 8461.2 4650.0 7734.1 9287.8 6768.5 8787.7 7672.6 5651.5 True False 6893.821996761299 6456.305982043622 8348.998959550132 3578.0143417838435 6660.353715283659 8707.032397756917 7370.88338767808 7429.762886256893 8078.157972076656 5453.642705182723 1.2640765758655108 1.1838520290132033 1.5309031799270394 0.656077879539775 1.2212669724318703 1.5965535089936167 1.3515523084549266 1.3623486700359406 1.4812407795618505 1.0 12.41300447000033 -6.538848885024236 24.81712149945675 1.383711568809276 1.1560518038714007 0.1259617414376717 0.24626580781578042 411.7334985032158 639816.9822952762 0.07981968287091888 0.07984155960663272 2.8916858841571885e-07 6.538848885024236 -0.22765976493787532 EEEPTGWEEPS(ph)PESIRR ddPTM_PC-9_Lapatinib_30min_R1 1 EEEPTGWEEPSPESIRR 17 1 Q8NDV7-2;Q8NDV7-6;Q8NDV7-5;Q8NDV7;H7C269 Q8NDV7-2 TNRC6A Trinucleotide repeat-containing gene 6A protein 1 EEEPTGWEEPS(0.797)PES(0.203)IRR 80.238 0.0026926 2701900.0 6048.8 7458.4 6068.0 5169.0 7682.7 7969.6 6316.9 5765.2 6371.8 6006.8 True False 5962.543002785937 7441.130533042728 5569.1124631573675 5549.145503278516 7230.818690769348 7628.758786044989 6643.958173170919 6033.072238897347 5654.140785971414 7045.067376442115 0.8463429353030726 1.0562185051522717 0.790498112449546 0.7876639365911833 1.0263661515783884 1.0828510755702168 0.9430652424116681 0.8563540867006095 0.802567311829863 1.0 12.782397788669547 -2.429993546212915 22.08957370134053 0.9199666281216806 0.28577269599494126 0.0 0.10994151362236282 0.0 0.0 0.026317640108979724 0.0 0.003715407502980613 2.429993546212915 -0.6341939321267394 EEEPTGWEEPSPES(ph)IRR ddPTM_PC-9_Lapatinib_30min_R1 1 EEEPTGWEEPSPESIRR 17 1 Q8NDV7-2;Q8NDV7-6;Q8NDV7-5;Q8NDV7;H7C269 Q8NDV7-2 TNRC6A Trinucleotide repeat-containing gene 6A protein 1 EEEPTGWEEPS(0.433)PES(0.567)IRR 80.507 0.0026128 2728500.0 6200.0 5135.1 6463.3 5255.5 5245.1 6287.5 4875.3 5211.7 4768.4 4573.0 True False 6111.58686305925 5123.209991449605 5931.912423059493 5642.0070018340575 4936.593530263358 6018.598281878369 5127.719178973891 5453.854608246252 4231.332578521939 5363.436956860523 1.1394907616545669 0.9552102565308169 1.105990891805266 1.0519387189994296 0.9204160634253046 1.1221532629706423 0.9560509837660869 1.0168581549690954 0.7889218448087698 1.0 12.388942078544957 -7.926140149233823 2.286006269768136 0.9000603298511114 1.0377932706772326 0.2731297334626921 0.08656596565081309 0.386255042081446 3.850073453802688 0.06158421023274311 0.02252940237771147 1.185386155762669e-08 7.926140149233823 0.1377329408261212 EEEQEDLTKDMDEPS(ph)PVPNVEEVTLPK ddPTM_PC-9_Lapatinib_30min_R1 1 EEEQEDLTKDMDEPSPVPNVEEVTLPK 27 1 F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 F8VXC8 SMARCC2 SWI/SNF complex subunit SMARCC2 1 EEEQEDLT(0.001)KDMDEPS(0.999)PVPNVEEVTLPK 85.376 4.0877e-07 3636300.0 21200.0 25944.0 23302.0 24918.0 24710.0 25221.0 21340.0 25703.0 23507.0 21037.0 True False 20897.684112396146 25883.9282619946 21386.199508321188 26750.55284401123 23256.606381729154 24142.35662302256 22444.880782578064 26897.25521341473 20859.394120316065 24673.217419959496 0.8469784769736144 1.0490698404439014 0.8667778970334342 1.0841939414991442 0.9425850705192438 0.9784843302800268 0.909686012997283 1.0901397558170136 0.8454265921331272 1.0 14.590658236783 -4.7374699221981365 24.548376833080695 0.9740924092648919 0.846977783765498 0.18243996202707502 0.08069302424088386 2814.9605754754352 2882760.8671936784 0.018088672535037542 1.0887188081712122 1.8303328647323908e-05 4.7374699221981365 -0.1271146254993939 EEERRQAER ddPTM_PC-9_AZD4547_30min_R2 1 EEERRQAER 9 2 Q8N4C8;Q8N4C8-4;I3L2I2;A0A590UJE1;Q8N4C8-3;Q8N4C8-2;Q8N4C8-5 Q8N4C8;Q8N4C8-3 MINK1 Misshapen-like kinase 1 0 90.601 0.017692 589390.0 845.02 0.0 600.92 784.75 447.53 997.54 0.0 0.0 0.0 2336.1 False True 1113.7187824921102 0.0 592.9514081658473 603.838011766639 385.39818443010773 935.1636661059068 0.0 0.0 0.0 2254.3138500534988 0.4940389211846788 0.0 0.2630296611768479 0.2678588927412698 0.17096030546987126 0.4148329506486924 0.0 0.0 0.0 1.0 11.138472669025436 -11.062797604245063 3.388588908684014 1.0227045958529917 0.17496600199299173 0.6704046543744673 0.17268365192216306 509364245.6230009 655236048.4139802 106309387.17788473 0.04403574039287908 8.653711167020287e-12 11.062797604245063 -0.84773859386 EEET(ph)SIDVAGKPNEVTK ddPTM_PC-9_AZD4547_30min_R2 2 EEETSIDVAGKPNEVTK 17 1 P53985 P53985 SLC16A1 Monocarboxylate transporter 1 1 EEET(0.573)S(0.427)IDVAGKPNEVTK;EEET(0.5)S(0.5)IDVAGKPNEVTK 97.76700000000001 0.0010248 12441100.0 52608.0 141623.0 85227.0 64981.0 80090.0 60031.0 96334.0 102914.0 69237.0 58236.0 True False 69336.24968562271 187399.86516128964 84096.83429366753 50000.63439644213 68970.88595403048 56277.2520801208 104907.53937631373 87011.00602845366 72896.72646986303 56197.175365658826 1.233803109043679 3.3346847762709197 1.4964601645273747 0.8897357219664941 1.2273016482635792 1.001424924187754 1.8667760202129484 1.5483163604273367 1.2971599728197198 1.0 15.778209997747119 -5.498354111973709 24.37767889502742 1.2893137337952871 2.3170764092897955 0.3552175868333821 0.5421904589203476 525.430581439083 522280.6627038164 0.1340665673980262 0.2766933265932359 3.174284789219401e-06 5.498354111973709 1.0277626754945084 EEET(ph)SIDVAGKPNEVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EEETSIDVAGKPNEVTK 17 1 P53985 P53985 SLC16A1 Monocarboxylate transporter 1 1 EEET(0.534)S(0.466)IDVAGKPNEVTK;EEET(0.827)S(0.173)IDVAGKPNEVTK 74.047 0.0071115 10984400.0 48151.0 64157.0 43436.0 31511.0 85260.0 28567.0 35477.0 31245.0 28514.0 33893.0 True False 56302.01327439988 70526.0829611582 44471.67897194732 29745.540830040383 68553.91504403124 27068.896230670634 32116.36172876265 30424.851856814013 28930.963306811816 40037.53260315964 1.4062308442542908 1.7614992327372465 1.110749741067654 0.7429414076254278 1.7122412543129886 0.6760880221808283 0.8021563678034477 0.7599082630384915 0.72259605989128 1.0 15.289065447357965 -5.465125734387866 0.525878244535213 0.7823197304324916 1.8237832659949107 0.40211550195920776 0.3054966879918077 2.2416807426664573 0.7856212240517105 0.20807461248221004 1.3251567299158413 3.426685647936469e-06 5.465125734387866 1.041463535562419 EEETS(ph)IDVAGKPNEVTK ddPTM_PC-9_Lapatinib_30min_R1 2 EEETSIDVAGKPNEVTK 17 1 P53985 P53985 SLC16A1 Monocarboxylate transporter 1 1 EEET(0.204)S(0.796)IDVAGKPNEVTK;EEET(0.238)S(0.762)IDVAGKPNEVTK 74.325 0.0045706 22018000.0 186005.0 198940.0 63201.0 39192.0 58172.0 40519.0 43942.0 41713.0 71389.0 24818.8 True False 183352.5345908602 198479.36665283702 58004.85774291513 42074.31042067937 54750.43733055234 38786.0968244023 46217.101750142734 43651.13826079321 63348.41906050308 29108.696511027756 6.29889196589059 6.818559071432265 1.9926985641882018 1.4454206290116642 1.88089622322354 1.3324573571924903 1.5877420595811806 1.4995909639669398 2.1762712403320323 1.0 14.82916261649619 -5.283882834620172 5.781808164072519 1.6080440145061357 6.585840554633193 0.9722709657895476 0.33419892705378784 0.020283850095519137 2.431949864978648 0.08170929152487409 0.18511062135257886 5.201363016722287e-06 5.283882834620172 4.977796540127057 EEEVERPVS(ph)SPGDPEQK ddPTM_PC-9_Lapatinib_30min_R1 1 EEEVERPVSSPGDPEQK 17 1 O43149 O43149 ZZEF1 Zinc finger ZZ-type and EF-hand domain-containing protein 1 1 EEEVERPVS(0.5)S(0.5)PGDPEQK 57.703 0.021071 3026000.0 31675.0 28462.0 24714.0 24956.0 24621.0 23269.0 24031.0 27697.0 28727.0 20774.0 True False 31223.308691516417 28396.09798770008 22682.110318798805 26791.347490775526 23172.84118674844 22273.83911268831 25275.20759541396 28983.903732869596 25491.462751279178 24364.758220384978 1.2814947067848665 1.1654578194805252 0.9309392735866194 1.0995942273853685 0.9510802847762588 0.9141826449175563 1.0373674701301672 1.1895830638130434 1.0462432058920057 1.0 14.572508285807062 -5.020952188891969 4.244887736516572 1.0251551607112666 1.2649880336450843 0.5383223924269991 0.07824212328315214 0.1559908283520612 6.65852077949785 0.021520714763783526 0.07825483462785425 9.52901062312333e-06 5.020952188891969 0.23983287293381772 EEEWDPEYT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 EEEWDPEYTPK 11 0 Q9NYF8-2;Q9NYF8;Q9NYF8-4;H0YF14;Q9Y2W1;A0A3B3ITZ9 Q9NYF8-2;Q9Y2W1 BCLAF1;THRAP3 Bcl-2-associated transcription factor 1;Thyroid hormone receptor-associated protein 3 1 EEEWDPEYT(1)PK;EEEWDPEYT(1)PK 179.67 0.0046459 32702000.0 193915.0 227484.0 184702.0 180565.0 222683.0 262640.0 218164.0 227670.0 233500.0 218878.0 True False 255575.9363174329 301013.75430792203 182252.73079785713 138938.5289514407 191767.30923837397 246217.0792810865 237580.1733603306 192488.83283613573 245842.33330030233 211215.14784127855 1.2100265484248793 1.4251523026848636 0.8628771783679751 0.6578057036697414 0.9079240347973574 1.1657169563714758 1.124825448309534 0.9113400947018485 1.163942718185369 1.0 17.688353779454324 -5.261515741246213 24.999999566293848 0.9696753057995755 1.3175894381871132 0.43955771631138973 0.15497987083587694 6.386347496318179 2091713.5443818027 0.043880232874793305 0.101961384850631 5.47626251582627e-06 5.261515741246213 0.34791413238753766 EEEWDPEYT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 EEEWDPEYTPK 11 0 Q9NYF8-2;Q9NYF8;Q9NYF8-4;H0YF14;Q9Y2W1;A0A3B3ITZ9 Q9NYF8-2;Q9Y2W1 BCLAF1;THRAP3 Bcl-2-associated transcription factor 1;Thyroid hormone receptor-associated protein 3 1 EEEWDPEYT(1)PK;EEEWDPEYT(1)PK;EEEWDPEY(0.012)T(0.988)PK;EEEWDPEYT(1)PK;EEEWDPEY(0.003)T(0.997)PK;EEEWDPEYT(1)PK 187.62 0.00024655 40541600.0 327554.0 366982.0 299952.0 315790.0 350562.0 266400.0 352495.0 250643.0 258822.0 246230.0 True False 383002.4227136047 403413.5476604538 307103.9932542953 298097.3101049943 281871.89263037377 252429.51502960292 319104.1217572002 244063.88682821052 262606.78210688283 290869.5498443925 1.3167498038845964 1.3869225839427652 1.0558134855249983 1.0248488034050605 0.9690663487503857 0.8678444174188945 1.0970695348753847 0.8390836612453184 0.9028335288013836 1.0 18.150012747884773 -5.411146654985664 2.153247559625826 0.9502049524205832 1.3667451577505616 0.8059048288273891 0.07576783838909606 0.13120093842159686 1.1580578335539626 0.021346375824041815 0.061886537188838034 3.880193153359087e-06 5.411146654985664 0.4165402053299784 EEEWDPEYT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 EEEWDPEYTPK 11 0 Q9NYF8-2;Q9NYF8;Q9NYF8-4;H0YF14;Q9Y2W1;A0A3B3ITZ9 Q9NYF8-2;Q9Y2W1 BCLAF1;THRAP3 Bcl-2-associated transcription factor 1;Thyroid hormone receptor-associated protein 3 1 EEEWDPEYT(1)PK;EEEWDPEY(0.002)T(0.998)PK;EEEWDPEYT(1)PK 164.48 0.0022859 34458400.0 211502.0 239026.0 187962.0 212513.0 215476.0 184244.0 188043.0 179017.0 192474.0 177866.0 True False 208485.94269528313 238472.54998271386 172508.48991430204 228141.91494258592 202802.12532211558 176364.3136137413 197778.94643853436 187334.78335368846 170795.55127892597 208609.90110845238 0.999405788447669 1.143150678446161 0.8269429638654501 1.0936293710430323 0.9721596350150349 0.8454263804192726 0.9480803422446991 0.8980148226823453 0.8187317589980188 1.0 17.67044810756331 -6.556409271098453 7.6956262022932105 0.8993101806110905 1.0140734697895097 0.2659194883840462 0.0895237112731858 0.27884724968291985 52.4700774593092 0.028353379681782125 0.02853124322918431 2.777094951236584e-07 6.556409271098453 0.11476328917841927 EEFASTCPDDEEIELAYEQVAK ddPTM_PC-9_Lapatinib_30min_R1 1 EEFASTCPDDEEIELAYEQVAK 22 0 O00299 O00299 CLIC1 Chloride intracellular channel protein 1 0 122.83 4.957800000000001e-07 1923500.0 20147.0 16131.0 17413.0 15691.0 16664.0 16046.0 13328.0 9772.9 13514.0 13439.0 False True 19859.700085492696 16093.649660585681 15981.37035612381 16844.96848364155 15683.856282684528 15359.749985052924 14018.058625595158 10226.984611725504 11991.911011271175 15761.913243658117 1.2599802941742078 1.0210467099900478 1.0139232534193774 1.0687134374641485 0.995047748343305 0.9744851242112371 0.8893627574834796 0.648841574853889 0.7608156970471956 1.0 13.94415504502947 -7.107546924290521 1.4646108760913306 0.7814390918203108 1.0744891314774614 0.5440369371837341 0.10737524526353316 0.29707634037143804 1.2701500242823838 0.05755321687538149 0.0388379046738993 7.806440891949877e-08 7.107546924290521 0.2930500396571506 EEGAAPS(ph)PTHVAELATMEVESAR ddPTM_PC-9_AZD4547_30min_R2 1 EEGAAPSPTHVAELATMEVESAR 23 0 Q9NRS6 Q9NRS6 SNX15 Sorting nexin-15 1 EEGAAPS(0.741)PT(0.256)HVAELAT(0.003)MEVESAR 50.493 0.021078 4824000.0 12068.0 18606.0 20075.0 11731.0 15968.0 20497.0 18850.0 25395.0 17299.0 16383.0 True False 15905.372970006385 24620.02563983923 19808.792383228018 9026.599192143276 13751.1188277433 19215.3193497732 20527.613482711346 21470.786269045802 18213.389823391553 15809.436156597096 1.0060683260591337 1.5572994125768096 1.2529727301477502 0.5709627530502775 0.8698045073546229 1.2154335650835255 1.2984405819018034 1.3580994322866025 1.1520581533068348 1.0 13.948498294457185 -6.964587844149826 24.920788028866472 1.2355550598937548 1.061889696494045 0.07724982012530168 0.25384939498977016 474.84217763986794 334161.9372727898 0.09894523874415309 0.08726120049414106 1.084956074858338e-07 6.964587844149826 -0.17366536339970984 EEGAAPS(ph)PTHVAELATMEVESAR ddPTM_PC-9_Lapatinib_30min_R1 1 EEGAAPSPTHVAELATMEVESAR 23 0 Q9NRS6 Q9NRS6 SNX15 Sorting nexin-15 1 EEGAAPS(0.888)PT(0.112)HVAELATMEVESAR 65.765 0.0011978 2859000.0 8576.1 9709.4 10811.0 9898.8 10593.0 10656.0 12193.0 9433.3 9536.4 8090.2 True False 8453.803241335876 9686.918480843764 9922.161311666825 10626.790773428778 9969.9405666393 10200.267720349242 12824.293879192799 9871.605555954753 8462.31020925606 9488.580290486108 0.8909450078440323 1.0209028310121928 1.0456950363391513 1.1199558256448456 1.0507304845842782 1.0750046274653668 1.351550335939224 1.0403669731132161 0.8918415558691055 1.0 13.21197652774651 -4.478700438261776 1.215022298801053 1.0874072481801509 0.6700574750870656 0.19216548890992202 0.11015509510991735 4.585848024260276 3.5868033572304094 0.03439319494727755 2.8753883268915827 3.3212346616755195e-05 4.478700438261776 -0.4173497730930853 EEGAQTLEEDRAQT(ph)PHEDGGPQPHR ddPTM_PC-9_Lapatinib_30min_R1 1 EEGAQTLEEDRAQTPHEDGGPQPHR 25 1 Q9BRZ2 Q9BRZ2 TRIM56 E3 ubiquitin-protein ligase TRIM56 1 EEGAQT(0.279)LEEDRAQT(0.721)PHEDGGPQPHR 42.813 0.030344 8013700.0 26850.0 18527.0 25560.0 21595.0 21165.0 16753.0 20081.0 17211.0 19071.0 18097.0 True False 26467.11407631305 18484.10186979549 23458.555464453257 23183.168338808206 19920.116311991 16036.513243150417 21120.69592291237 18010.68589184456 16923.023153466962 21225.04233726325 1.2469757965969603 0.8708628975191398 1.1052300905552868 1.0922554579835733 0.9385195089584681 0.7555468200407914 0.9950838065388597 0.8485583022948567 0.7973139880977506 1.0 14.37347981105209 -6.41557020571245 4.43254557015166 0.8743206502978307 1.0646687052477894 0.4128766809542126 0.11172650622830635 0.23388044111920456 7.5775889937307 0.03410948065272023 0.03854077363065152 3.8408716469264635e-07 6.41557020571245 0.19034805494995877 EEGDLGPVYGFQWR ddPTM_PC-9_Lapatinib_30min_R1 1 EEGDLGPVYGFQWR 14 0 P04818-2;P04818 P04818-2 TYMS Thymidylate synthase 0 103.22 0.0087949 0.0 3875.7 4360.1 4412.2 5452.8 4994.4 4016.6 4544.3 4405.9 4891.7 4218.0 False True 3820.4318072836645 4350.004456333745 4049.4459475845338 5853.817102007563 4700.639211368199 3844.8193811519122 4779.581618569328 4610.614198528728 4340.745234115377 4947.0756798682905 0.7722606352740047 0.8793082495252141 0.8185534666597915 1.1832883668687708 0.9501854258056038 0.7771903301981172 0.9661428140304048 0.9319878038840674 0.8774365938608287 1.0 12.272360254531685 EEGGEGT(ph)PVKQDLSAPPGYTLTENVAR ddPTM_PC-9_AZD4547_30min_R2 1 EEGGEGTPVKQDLSAPPGYTLTENVAR 27 1 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;Q9Y4B5-4 Q9Y4B5;Q9Y4B5-4 MTCL1 Microtubule cross-linking factor 1 1 EEGGEGT(1)PVKQDLSAPPGYTLTENVAR 62.678000000000004 0.00073714 5243200.0 13032.0 11002.0 14472.0 16056.0 14416.0 14715.0 15431.0 16120.0 14555.0 15267.0 True False 17175.904917560754 14558.181344163791 14280.091824163173 12354.537262727177 12414.587238273256 13794.868723808982 16804.329106191974 13629.0244007489 15324.347585378582 14732.506976913133 1.1658507913470937 0.9881672798103865 0.9692913668081796 0.8385902875924376 0.8426663064017401 0.9363558249404873 1.1406292990409257 0.9250987915435257 1.0401724302179463 1.0 13.84671532896012 -9.77124843055828 15.590539908634147 1.0000021000829102 0.9759195967425015 0.0 0.10406216186507819 0.0 0.0 0.10578636452369446 0.0256569620400756 1.693368861318013e-10 9.77124843055828 -0.024082503340408734 EEGGEGT(ph)PVKQDLSAPPGYTLTENVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EEGGEGTPVKQDLSAPPGYTLTENVAR 27 1 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;Q9Y4B5-4 Q9Y4B5;Q9Y4B5-4 MTCL1 Microtubule cross-linking factor 1 1 EEGGEGT(0.826)PVKQDLS(0.03)APPGY(0.043)T(0.05)LT(0.05)ENVAR;EEGGEGT(0.994)PVKQDLS(0.005)APPGYTLTENVAR 70.679 0.00013668 7036200.0 26910.8 28314.2 30938.0 32835.0 34801.0 26400.7 30403.2 23647.5 29848.0 21199.8 True False 31466.266927472334 31125.046653971145 31675.679253018363 30995.36140250628 27981.993871068797 25016.200816223827 27523.18879589361 23026.778181597343 30284.470533131756 25043.15592247555 1.2564816920391497 1.2428564015782557 1.2648437501676977 1.2376779307870214 1.117350942416795 0.9989236537784947 1.099030365066421 0.91948388026173 1.2092912980648844 1.0 14.612128760781948 -6.379352184200445 2.7939890511593277 1.0438292871136778 1.2535578626866004 0.6486571812446345 0.07115488807217012 0.1615487024032048 2.440515465746225 0.022047919100913804 0.025627829104838747 4.174916711069395e-07 6.379352184200445 0.20972857557292257 EEGGEGT(ph)PVKQDLSAPPGYTLTENVAR ddPTM_PC-9_Lapatinib_30min_R1 2 EEGGEGTPVKQDLSAPPGYTLTENVAR 27 1 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;Q9Y4B5-4 Q9Y4B5;Q9Y4B5-4 MTCL1 Microtubule cross-linking factor 1 1 EEGGEGT(0.712)PVKQDLS(0.266)APPGY(0.006)T(0.007)LT(0.007)ENVAR;EEGGEGT(0.989)PVKQDLS(0.008)APPGYT(0.001)LT(0.001)ENVAR 70.316 0.00014676 12763800.0 46335.5 42628.5 43979.6 35123.5 39878.9 35668.2 32797.7 28830.4 33642.6 31119.4 True False 45674.74727310997 42529.79632733723 40363.76705416542 37706.599358561216 37533.301506934 34142.75423263522 34495.80442562142 30169.965634549713 29853.416115716416 36498.34682600597 1.2514196188350535 1.165252676513932 1.1059067208327706 1.0331043084859488 1.0283562070869086 0.93546029345931 0.9451333396021738 0.8266118402122496 0.8179388578346547 1.0 15.155543498886313 -5.724938122071358 0.5739454686988437 0.8737219631635613 1.299877319964881 0.8311483863935216 0.054020913270247856 0.5938865572935329 0.30454570120800417 0.03524740311331719 0.14907979734203158 1.8839174894180092e-06 5.724938122071358 0.42615535680131966 EEGS(ph)LSDTEADAVSGQLPDPTTNPSAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEGSLSDTEADAVSGQLPDPTTNPSAGK 28 0 Q8N1G4 Q8N1G4 LRRC47 Leucine-rich repeat-containing protein 47 1 EEGS(0.599)LS(0.392)DT(0.009)EADAVSGQLPDPTTNPSAGK 126.74 2.9471999999999994e-11 7484100.0 25006.0 52698.0 38275.0 27114.0 37825.0 21206.0 39572.0 18305.0 20545.0 24174.0 True False 29239.021908987226 57929.50917105097 39187.6211587458 25594.89048477405 30413.462779034424 20093.920028970544 35823.45368353009 17824.51314575068 20845.43175767864 28556.554838721302 1.0238987887061408 2.028588865086112 1.3722811235481842 0.8962877570255295 1.065025628994827 0.7036535094115822 1.2544739337728241 0.6241828976365701 0.7299701198343873 1.0 14.801534317708553 -5.678072179935155 4.015956736339142 0.8926518050425059 1.5623652132413997 0.46449213010201884 0.2862487921094415 0.17030491365075112 5.1948880496995296 0.07590050333890687 0.13530886578648924 2.0985910678731317e-06 5.678072179935155 0.6697134081988938 EEGSLS(ph)DTEADAVSGQLPDPTTNPSAGK ddPTM_PC-9_Lapatinib_30min_R1 1 EEGSLSDTEADAVSGQLPDPTTNPSAGK 28 0 Q8N1G4 Q8N1G4 LRRC47 Leucine-rich repeat-containing protein 47 1 EEGS(0.212)LS(0.71)DT(0.078)EADAVSGQLPDPTTNPSAGK 105.91 3.7771e-05 0.0 8513.5 19381.0 14605.0 12424.0 21250.0 19907.0 23860.0 23700.0 18525.0 19857.0 True False 8392.095928815308 19336.124485265085 13404.233276930352 13337.702405249045 20000.116779107448 19055.624015483532 25095.354052123384 24801.188521103708 16438.51942310186 23289.25599221066 0.3603419504522658 0.830259433437129 0.5755543792989154 0.572697659801154 0.8587701035102495 0.8182152328892297 1.0775506980779803 1.064919743653414 0.7058413299505961 1.0 14.507376930927634 -6.487160681256335 1.7973115293901964 0.9561067948392491 0.5971805470186038 0.5499259633780814 0.14915179287547872 0.27609744395617436 1.7930573948758994 0.05509788199761002 0.06162978409669763 3.2571616949980323e-07 6.487160681256335 -0.3589262478206453 EEGSPLELER ddPTM_PC-9_Lapatinib_30min_R1 2 EEGSPLELER 10 0 F5GZS6;J3KPF3;P08195-2;P08195-3;P08195;P08195-4;F5GZI0 F5GZS6 SLC3A2 4F2 cell-surface antigen heavy chain 0 ; 104.05 0.01226 4150300.0 33716.0 47826.0 29115.0 27917.0 36292.0 30981.0 39203.0 37382.0 39359.0 35165.0 False True 33235.20365724285 47715.26183542067 26721.277087150087 29970.10930838195 34157.37591281728 29656.01485023837 41232.73951824781 39118.90418970039 34925.9749513558 41243.223395582834 0.8058342903625314 1.1569236812011885 0.6478949724868485 0.7266674823382442 0.8281936546326191 0.7190518201206975 0.9997458036382251 0.9484928909288415 0.8468294201053254 1.0 15.331869471593263 -10.394041175389283 6.469169422273972 1.0000000072291957 0.8548785986114704 0.08745263039815832 0.142088993237083 1.5222654424344384e-08 2.591608096954345e-09 0.1406396352175882 0.034110119799258355 4.0360712522757294e-11 10.394041175389283 -0.14512140861772527 EEGTVDAGT(ph)SPPPR ddPTM_PC-9_AZD4547_30min_R2 1 EEGTVDAGTSPPPR 14 0 I3L0L0 I3L0L0 RUNX2 1 EEGT(0.002)VDAGT(0.814)S(0.184)PPPR 84.734 0.022479 0.0 14142.0 14984.0 16033.0 18889.0 14392.0 17089.0 18292.0 20157.0 13572.0 17851.0 True False 18638.86182812647 19827.284971909656 15820.391944223898 14534.43288214087 12393.919224003112 16020.42212852 19919.95256370059 17042.198811780127 14289.388212212842 17226.041923421533 1.082016513775227 1.151006427364566 0.9183997121656583 0.8437476784715708 0.7194873482312623 0.930011792595123 1.1563859331269977 0.989327605699633 0.8295224332865552 1.0 14.072303627053309 -5.267406205014922 23.695144796350093 0.9214145541441878 1.1165114821446422 0.3253530828549489 0.11122639923554017 269.5004714072732 1070237.0509289273 0.032302013422108 0.07033679682879736 5.40248780199899e-06 5.267406205014922 0.19509692800045442 EEGTVDAGTS(ph)PPPR ddPTM_PC-9_AZD4547_30min_R2 1 EEGTVDAGTSPPPR 14 0 I3L0L0 I3L0L0 RUNX2 1 EEGTVDAGT(0.219)S(0.781)PPPR 95.18299999999999 0.014444 0.0 19683.0 16999.0 20713.0 25320.0 24151.0 25098.0 19567.0 23581.0 22421.0 22617.0 True False 25941.784568166702 22493.594316437026 20438.33208636622 19482.865190100405 20798.050526605 23528.61809243342 21308.42509369829 19937.09828747269 23606.128286621293 21825.185714079016 1.18861689921072 1.0306255631046857 0.9364562736885137 0.8926780942593481 0.9529380780108812 1.0780489293731668 0.9763227389150062 0.913490430214834 1.0816003398950884 1.0 14.413706309584732 -4.80616199451497 3.1386165061395856 0.9754894214112046 1.2144074675365593 0.5283280246041018 0.0594065264068337 0.2600573730767255 3.974152240885213 0.015572338592106588 0.15057049504160577 1.5625646876782327e-05 4.80616199451497 0.2389180461253546 EEHGGLIR ddPTM_PC-9_AZD4547_30min_R2 2 EEHGGLIR 8 0 P26368;P26368-2 P26368 U2AF2 Splicing factor U2AF 65 kDa subunit 0 ; 139.97 0.0021833 4588200.0 23739.4 30855.0 27300.0 31072.0 24817.0 33324.0 29242.0 34167.0 30068.0 23598.0 False True 31288.03538980523 40828.27534758897 26937.98416249689 23908.83045761452 21371.587922601808 31240.245012042862 31844.4813507398 28887.27522955258 31657.33309496139 22771.841202672193 1.3739791662579175 1.7929281600118447 1.1829515199383973 1.0499296145982655 0.9385094394604302 1.371880505137939 1.3984148698087253 1.268552462335051 1.3901964629564743 1.0 14.474963323925833 -5.280344120684187 24.688695643600983 1.208163959260089 1.5834536607495584 0.41612904647949267 0.18145518922417514 610.5889121127784 797399.8020438828 0.04959516895332597 0.10352556334084607 5.2439178475975935e-06 5.280344120684187 0.3752897014894694 EEHGGLIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEHGGLIR 8 0 P26368;P26368-2 P26368 U2AF2 Splicing factor U2AF 65 kDa subunit 0 82.241 0.014057 2724300.0 14969.0 24077.0 23925.0 15994.0 20402.0 13388.0 21419.0 11040.0 12312.0 15940.0 False True 17502.956048773496 26467.205440650378 24495.462736067773 15097.908033247631 16404.374556982435 12685.909711772982 19390.03725986887 10750.211697846906 12492.039707984386 18829.795819029423 0.9295350951753274 1.4056023599524416 1.3008883883548337 0.8018094395898685 0.8711923758835529 0.6737146718793722 1.029752921711093 0.5709149372178919 0.6634187554683896 1.0 14.200729735716632 -5.767956689090023 24.650468431199936 0.7907492634756278 1.2313680168282417 0.5300032319877699 0.1766446048502407 88.59322970358653 335088.5160033808 0.048500366591522286 0.07392605759054102 1.7062525400607118e-06 5.767956689090023 0.4406187533526139 EEHGGLIR ddPTM_PC-9_Lapatinib_30min_R1 1 EEHGGLIR 8 0 P26368;P26368-2 P26368 U2AF2 Splicing factor U2AF 65 kDa subunit 0 95.815 0.0052967 3428000.0 14594.0 15141.0 16486.0 13206.0 16072.0 16530.0 19052.0 18764.0 18241.0 17529.0 False True 14385.886883788178 15105.94194476026 15130.584717800326 14177.213293924575 15126.676558767744 15823.050433312032 20038.41933784806 19635.84394134979 16186.506493754434 20558.864294075673 0.6997413221864437 0.7347653901832141 0.7359640348499414 0.6895912678410908 0.7357739387932392 0.769646134483784 0.9746851310080593 0.9551035339538739 0.7873249349877174 1.0 14.327472949404187 -7.11934583318521 4.124997320355575 0.9247840767453124 0.7216380749186943 0.7649890422654518 0.05520843257160335 0.11516996723355487 3.309130476082239 0.0215770424618408 0.016561039612246514 7.597210622677483e-08 7.11934583318521 -0.20314600182661813 EEHGGLIRS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 EEHGGLIRSPR 11 1 P26368;P26368-2 P26368 U2AF2 Splicing factor U2AF 65 kDa subunit 1 EEHGGLIRS(1)PR;EEHGGLIRS(1)PR 59.294 0.030982 331077000.0 302842.0 298995.0 400951.0 465519.0 445754.0 401315.0 316114.0 474756.0 398596.0 415344.0 True False 399139.4564950835 395639.2865840986 395634.1277632706 358200.7867468545 383868.75137411716 376220.7096089298 344247.5336060378 401393.3690075652 419664.9708101377 400802.93298087537 0.9958496399379612 0.9871167449839416 0.9871038737686797 0.8937079978003712 0.9577493570697841 0.9386675561749981 0.8588947467169953 1.0014731329990492 1.0470606282468555 1.0 18.61253354030896 -7.9840848956646475 24.969830328257437 1.02377587553849 0.9457851049289822 0.3815888352606719 0.041815352475826136 232.7502209221288 365170.7529744439 0.023999572501869425 0.011523648040657648 1.0373256201123269e-08 7.9840848956646475 -0.07799077060950788 EEHGGLIRS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EEHGGLIRSPR 11 1 P26368;P26368-2 P26368 U2AF2 Splicing factor U2AF 65 kDa subunit 1 EEHGGLIRS(1)PR;EEHGGLIRS(1)PR;EEHGGLIRS(1)PR;EEHGGLIRS(1)PR 76.01 0.0099508 586265000.0 808168.0 836269.0 1022668.0 917645.0 1114709.0 861914.0 940267.0 949573.0 821185.0 743569.0 True False 944974.8803544104 919288.2596107166 1047052.2836099898 866232.3256952303 896289.7734555113 816713.7125271199 851198.1028164313 924647.7149057582 833193.2770956093 878372.1736110364 1.075825155605245 1.0465817192631137 1.1920371740665465 0.9861791524361495 1.020398642378224 0.9298037176764888 0.9690631470224165 1.0526832960844836 0.9485652006373402 1.0 19.744472825650092 -5.802033417720489 24.965122282704748 0.9871677402640738 1.0989913875359838 0.5636498453861337 0.04755182366399739 106.34418976571747 65400.63025032646 0.013247086250007107 0.01964886935520478 1.5774898816864526e-06 5.802033417720489 0.11182364727190997 EEHGGLIRS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 5 EEHGGLIRSPR 11 1 P26368;P26368-2 P26368 U2AF2 Splicing factor U2AF 65 kDa subunit 1 EEHGGLIRS(1)PR;EEHGGLIRS(1)PR;EEHGGLIRS(1)PR;EEHGGLIRS(1)PR;EEHGGLIRS(1)PR 92.906 0.0034875999999999996 852157800.0 309085.0 428289.0 446524.0 374719.0 448186.0 401211.0 376000.0 414695.0 403668.0 323203.0 True False 304677.39122075355 427297.3231344981 409812.520352485 402277.08528593904 421824.5806475782 384052.14079852146 395467.44021787046 433963.243618528 358202.65902751323 379068.2079090737 0.8037534798851712 1.1272307047099899 1.0811049615925215 1.0612261247253751 1.1127933491820563 1.01314785251166 1.0432619564675558 1.1448157206647673 0.944955687535354 1.0 18.53209793855485 -4.752792105330564 24.999601179376203 1.0638112210720199 0.8037529897599974 0.6283018855976903 0.05871656127763945 200.50189964226254 579615.1724395183 0.013669162276242847 0.15723086957188753 1.7668834168304812e-05 4.752792105330564 -0.26005823131202244 EEHLCTQR ddPTM_PC-9_AZD4547_30min_R2 3 EEHLCTQR 8 0 A0A087WWU8;P06753-5;P06753-2;P06753-7;J3KN67 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 ;; 112.41 0.0031309000000000003 44116200.0 73135.2 93463.0 117281.4 117454.0 105042.0 102647.0 98234.3 134715.0 107397.4 86168.9 False True 96390.67229333865 123673.08698141958 115726.17200569445 90376.79494621066 90458.73145690195 96228.4668632565 106976.9623949447 113897.89219273516 113074.20730786247 83152.15303877178 1.1592083761005452 1.4873107004668165 1.3917399342832917 1.0868846042275082 1.087869984734169 1.1572576697850212 1.2865206550341999 1.3697527728431447 1.3598470174926052 1.0 16.34346599890258 -5.739005188988101 24.99629383377352 1.206074940544238 1.3602088377608603 0.20250173244588898 0.1369258488858924 404.23909145227356 450401.9735048336 0.03908916401750777 0.06764176033498982 1.8238739103859326e-06 5.739005188988101 0.1541338972166224 EEHLCTQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EEHLCTQR 8 0 A0A087WWU8;P06753-5;P06753-2;P06753-7;J3KN67 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 ;; 145.16 0.0012343 35542400.0 94419.0 132230.0 137757.0 110422.0 125133.0 94834.0 116721.0 96425.0 92629.0 79294.0 False True 110402.27183974517 145356.92052237425 141041.64932633156 104235.41333295422 100614.08692475643 89860.73809428421 105664.34189313946 93893.94592073273 93983.52388814856 93669.37450904139 1.1786378676958993 1.551808382240705 1.505739203080913 1.1128014239370516 1.074140693819245 0.9593395767323124 1.128056447979593 1.0023974902455408 1.0033538110055047 1.0 16.515289810933723 -5.8645605045727764 4.756932717774505 1.035020491647792 1.424788451724349 0.7389473262033321 0.10200212793838946 0.10024555448663923 3.7818144858489475 0.028791736045363853 0.04401412782926309 1.3659647604203816e-06 5.8645605045727764 0.3897679600765569 EEHLCTQR ddPTM_PC-9_Lapatinib_30min_R1 3 EEHLCTQR 8 0 A0A087WWU8;P06753-5;P06753-2;P06753-7;J3KN67 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 ;; 143.73 0.0014398 53595400.0 196439.0 272996.0 249182.0 232279.0 259051.0 257878.0 238196.0 236219.0 252774.0 221713.0 False True 193637.74383749944 272363.89453482366 228695.21783033587 249361.57252002892 243814.12949386163 246849.159082979 250528.62337802062 247194.59709985607 224303.93029177602 260035.79663599696 0.7446580291734112 1.0474092338759182 0.8794759059671611 0.9589509434698715 0.9376175613050586 0.9492891450961389 0.9634389827055825 0.9506175699566616 0.8625886635360474 1.0 17.98835071336142 -4.742351335097949 24.998796296719522 0.9464860595417234 0.744657358804627 0.6008241529713023 0.05012457411600102 881.2104836215415 1154023.8015847905 0.011540372690752435 0.4196211871247757 1.8098753491499567e-05 4.742351335097949 -0.20182870073709636 EEHRLS(ph)ATQQSELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEHRLSATQQSELR 14 1 A0A2R8YF49;A0A2R8YFR7;Q12774;A0A5F9ZGZ6;A0A5F9ZH52;A5YM69 A0A2R8YF49;A0A5F9ZH52 ARHGEF5;ARHGEF35 Rho guanine nucleotide exchange factor 5;Rho guanine nucleotide exchange factor 35 1 EEHRLS(0.971)AT(0.024)QQS(0.004)ELR 58.711999999999996 0.029406 8715700.0 14131.0 17412.0 24786.0 15325.0 25035.0 16895.0 22727.0 16265.0 13652.0 16391.0 True False 16523.099200027933 19140.548288100857 25376.992241428467 14466.389934320365 20129.571465251203 16008.99645805231 20574.134030768917 15838.06098419201 13851.634672953443 19362.558548915404 0.8533530916529354 0.9885340431506671 1.3106218466593074 0.7471321467033447 1.0396132006210907 0.8268017068926594 1.062573108754854 0.8179735619226407 0.7153824551626389 1.0 14.240981981022767 -6.9043079499594695 0.8458192670052347 0.858154706033849 1.0071715489491913 0.07658773017654164 0.1639194841831459 1.4950341288987976 2.274384069491139 0.1130098820310116 0.09200578840782492 1.2464993318261823e-07 6.9043079499594695 0.14901684291534223 EEIFGPVQQIMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EEIFGPVQQIMK 12 0 P00352 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ; 114.89 0.009610500000000001 4312900.0 53756.0 68640.0 52750.0 55729.0 60896.0 61785.0 65781.0 54272.0 56689.0 57310.0 False True 62855.82907060378 75454.1255740434 54007.76005548904 52606.68480585576 48963.865945593694 58544.88583372373 59549.74746680209 52847.41750593723 57517.969379948605 67699.8493342896 0.9284485813289344 1.1145390472209855 0.79775303175061 0.7770576348862089 0.723249260184007 0.8647712869291583 0.8796141801255157 0.7806135172470806 0.8496026201762324 1.0 16.046865002641965 -5.273856666152744 24.89912897165415 0.8229746531465832 1.0214938157787348 0.4452005660781456 0.0829463573183037 504.2665075399098 1011154.9985787788 0.02077023421770836 0.04373607022295314 5.322839043978972e-06 5.273856666152744 0.19851916263215152 EEIFGPVQQIMK ddPTM_PC-9_Lapatinib_30min_R1 5 EEIFGPVQQIMK 12 0 P00352 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ;;;; 192.12 0.00025115 71673300.0 295856.0 260105.0 277358.0 274238.0 280740.0 234353.0 278371.0 246025.0 245584.0 262789.0 False True 291637.0391866546 259502.74285330408 254554.69587284137 294406.37735114933 264227.42515607644 224330.26849352536 292783.68830023636 257456.21965841914 217923.74380583252 308211.7285056676 0.9462230415455841 0.8419625823828186 0.8259085308239996 0.95520822253763 0.8572919221379263 0.7278446851492877 0.9499433708112521 0.835322591085903 0.7070585693231503 1.0 18.23356223679248 -6.51798336654986 24.98312413053216 0.8350505755294069 0.8867674026262079 0.05424986779042851 0.09067204124853973 643.2332503367846 3282700.5072172834 0.02873817473513263 0.029497756743431823 3.034007384252626e-07 6.51798336654986 0.05171682709680103 EEIFRES(ph)PIPIEIPPAAVPSYVPESR ddPTM_PC-9_Lapatinib_30min_R1 1 EEIFRESPIPIEIPPAAVPSYVPESR 26 1 Q5TC82-2;Q5TC82 Q5TC82-2 RC3H1 Roquin-1 1 EEIFRES(1)PIPIEIPPAAVPSYVPESR 73.435 0.0013009 0.0 5612.7 3594.3 4406.7 3976.5 5104.4 4002.8 3761.9 2628.6 3405.9 2266.1 True False 5532.661868756881 3585.977619183133 4044.398136353917 4268.945075215134 4804.1692276365175 3831.609574982544 3956.6727748819317 2750.734352176084 3022.291676283002 2657.792365611552 2.0816757322138773 1.3492316651899205 1.5217133545431454 1.6061996153084965 1.8075788348993502 1.44165120818266 1.4887065017103056 1.034969619059443 1.137143636721817 1.0 11.376012686189943 -7.61120304419818 1.6626479032200059 1.0337372274811174 1.6333387221021225 0.6356530393319937 0.1947218218958294 0.25190635524899074 1.3501510315488319 0.13178314148870457 0.05929552415461256 2.447918507389099e-08 7.61120304419818 0.5996014946210051 EEILAQAK ddPTM_PC-9_Lapatinib_30min_R1 2 EEILAQAK 8 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 130.27 0.017289 14947200.0 108220.0 114356.0 107903.0 110573.0 101265.0 99419.0 111104.0 99370.0 100881.0 91339.0 False True 106676.76295488243 114091.21570801144 99031.63185762522 118704.90728071473 95308.7917946501 95167.08112700848 116856.4214839528 103987.09296802005 89518.71945597502 107126.8244484328 0.9957987973986197 1.0650107131937907 0.9244335615053695 1.1080782791041774 0.8896818540582102 0.8883590232138232 1.0908231629716933 0.9706914538298098 0.8356330911224413 1.0 16.708960249139047 -6.277095101833866 24.978262785269788 0.9487719746027714 1.0192434616056134 0.18543183791664108 0.07921485426896459 1592.1992735829642 2540302.9521470433 0.024772666419619935 0.028185646254860874 5.2832954546876e-07 6.277095101833866 0.070471487002842 EEIPVQEKT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 EEIPVQEKTPK 11 1 Q96B01-3;Q96B01-2;Q96B01;H0YGT5;F5H1Y0;H0YFK6;F5H4V6;F5H031;F5H710 Q96B01-3 RAD51AP1 RAD51-associated protein 1 1 EEIPVQEKT(1)PK 67.726 0.028102999999999996 5315300.0 35736.0 32037.0 37215.0 51739.0 48784.0 47178.0 39599.0 39416.0 38540.0 51641.0 True False 47099.304645023876 42392.33373231912 36721.504784150966 39811.37290958155 42011.183673135594 44227.95220196127 43123.23428657224 33325.16288957311 40577.14571903059 49833.06430829709 0.9451416504038254 0.8506868746833394 0.7368903617279043 0.7988947391090506 0.8430383372218359 0.8875222267757958 0.8653538546172108 0.6687359758453495 0.8142615005169286 1.0 15.604815669735023 EEIPVQEKT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEIPVQEKTPK 11 1 Q96B01-3;Q96B01-2;Q96B01;H0YGT5;F5H1Y0;H0YFK6;F5H4V6;F5H031;F5H710 Q96B01-3 RAD51AP1 RAD51-associated protein 1 1 EEIPVQEKT(1)PK 60.901 0.044410000000000005 8734600.0 70005.0 60517.0 55912.0 72871.0 72342.0 78687.0 74459.0 89467.0 66906.0 56528.0 True False 81855.46383822495 66524.72781708026 57245.1541274408 68788.2741209695 58167.104411392254 74560.5151994532 67405.70448352296 87118.58604812213 67884.37367628362 66776.07892459813 1.2258201612983908 0.9962359109494631 0.8572703736031071 1.030133473375151 0.8710769687012184 1.1165752227477308 1.0094289088108301 1.3046376404714366 1.0165971822475073 1.0 16.02704376072945 -6.821028934275874 24.99997264117479 1.1034868262050117 0.9902901961874206 0.11629048440936463 0.125196865523652 141.1113808503674 59199.885575127664 0.043667647396038775 0.038511259740876956 1.5099795504905372e-07 6.821028934275874 -0.11319663001759106 EEIPVQEKT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 EEIPVQEKTPK 11 1 Q96B01-3;Q96B01-2;Q96B01;H0YGT5;F5H1Y0;H0YFK6;F5H4V6;F5H031;F5H710 Q96B01-3 RAD51AP1 RAD51-associated protein 1 1 EEIPVQEKT(1)PK 60.901 0.044410000000000005 23560000.0 154990.0 119320.0 96122.0 135360.0 121840.0 108210.0 93174.0 89401.0 102550.0 110380.0 True False 152779.814178315 119043.7218709991 88219.22020165002 145314.82594772326 114673.61074665643 103582.1105498303 97998.09381611664 93554.89683439618 90999.73910062597 129459.03592789508 1.1801402125642966 0.9195474152712136 0.6814450576534925 1.1224772755812842 0.8857907053357503 0.800114953795288 0.7569814892696924 0.7226602311985665 0.7029230400828118 1.0 16.98213613981705 -6.674299046055369 3.5063264734114283 0.7750539912573472 0.9557366771816955 0.23776237873235806 0.14657314315092845 0.35073415863722596 8.479785247426205 0.05128141083562436 0.05023192729122265 2.1169029783649194e-07 6.674299046055369 0.18068268592434833 EEIQETQT(ph)PTHSR ddPTM_PC-9_AZD4547_30min_R2 1 EEIQETQTPTHSR 13 0 H7BZL0;Q9BYG3 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 EEIQET(0.003)QT(0.963)PT(0.032)HS(0.002)R 81.01 0.025404 10950000.0 25161.0 26786.0 28057.0 38496.0 34404.0 32070.0 30943.0 40605.0 31588.0 29462.0 True False 33161.67461868831 35444.0506712208 27684.945847881867 29621.34195727113 29627.598456267584 30064.657830278917 33696.86705546618 34330.430260075 33257.67719181989 28430.544347534884 1.1664101191071161 1.2466891325735039 0.9737747371088353 1.0418844463609258 1.0421045089429142 1.0574773899074401 1.1852346773088753 1.2075192736523062 1.1697868596984338 1.0 14.795154101497387 -7.261972286182776 24.915470348226574 1.1579284752695382 1.0858851740432014 0.06497420637315077 0.08823697965904062 104.2354400243704 4873210.056790771 0.037045981546864754 0.026722014421897502 5.470508709684665e-08 7.261972286182776 -0.07204330122633684 EEIQETQT(ph)PTHSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EEIQETQTPTHSR 13 0 H7BZL0;Q9BYG3 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 EEIQET(0.005)QT(0.989)PT(0.006)HSR;EEIQET(0.001)QT(0.98)PT(0.009)HS(0.009)R 114.06 0.00065115 22334000.0 50347.0 48463.0 68619.0 55664.0 73729.0 53009.0 55555.0 53629.0 49439.0 41787.0 True False 58869.75270142284 53274.08635919092 70255.13719900681 52545.326545122916 59282.331718055044 50229.11472298879 50292.4282166308 52221.295574622396 50161.95184560104 49362.65231428998 1.1925970332104836 1.079238733364589 1.4232447793059262 1.0644753489048557 1.2009551541235441 1.0175529953938065 1.0188356147562934 1.057911054740972 1.0161923943272324 1.0 15.591132293847771 -6.761734650472582 24.999830372983904 1.0255139071091783 1.1915829066087344 0.4609395520906491 0.09188527760619214 7.4835296231755315 633577.4312215699 0.030586974871012442 0.028672933609101902 1.7308735824245264e-07 6.761734650472582 0.1660689994995561 EEIQETQT(ph)PTHSR ddPTM_PC-9_Lapatinib_30min_R1 2 EEIQETQTPTHSR 13 0 H7BZL0;Q9BYG3 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 EEIQET(0.112)QT(0.887)PT(0.001)HSR;EEIQETQT(0.998)PT(0.002)HSR 124.81 0.00036471 21958300.0 37483.0 38603.0 46694.0 42831.0 44223.0 39291.0 39914.0 35837.0 42763.0 32674.0 True False 36948.48554645965 38513.61712526126 42854.999564052436 45980.93462002749 41621.89008576321 37610.61552179449 41980.55161929811 37502.117849400594 37946.58062564668 38321.657364631705 0.964167212156137 1.0050091716755112 1.1182971330359188 1.199868110674795 1.0861192586147748 0.9814454308154882 1.0954784971811609 0.9786141943853532 0.9902124082104238 1.0 15.225872336762084 -7.685510237237202 1.387581965440355 0.985170679479441 1.0710395659650056 0.16803007695126515 0.06771057559485115 0.8266583810478068 2.9739487938257017 0.0587452999641585 0.024103390907663447 2.0629550385349393e-08 7.685510237237202 0.08586888648556457 EEKDKDDQEWESPS(ph)PPKPTVFISGVIAR ddPTM_PC-9_Lapatinib_30min_R1 2 EEKDKDDQEWESPSPPKPTVFISGVIAR 28 3 P51397 P51397 DAP Death-associated protein 1 1 EEKDKDDQEWES(0.112)PS(0.885)PPKPT(0.003)VFIS(0.001)GVIAR;EEKDKDDQEWES(0.191)PS(0.807)PPKPT(0.002)VFISGVIAR 45.638999999999996 0.025472 9852700.0 28844.0 22030.0 15104.099999999999 24495.0 25507.0 19458.8 21352.0 22628.0 19413.2 20526.4 True False 28432.67927065822 21978.99088851918 13862.299201512064 26296.444012924596 24006.72840869146 18626.592484678287 22457.50208386163 23679.379487575316 17226.68098594122 24074.36089029124 1.1810356835734157 0.912962590727919 0.575811722050843 1.092300814661688 0.9971906842342363 0.7737107776011641 0.9328389728060587 0.9835932756630225 0.7155613004409365 1.0 14.55520987844285 EEKS(ph)VEYEGDLK ddPTM_PC-9_AZD4547_30min_R2 2 EEKSVEYEGDLK 12 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0;H7C3N7 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 EEKS(0.999)VEY(0.001)EGDLK;EEKS(1)VEYEGDLK 123.02 0.0018046 19479000.0 48670.0 52157.0 45048.0 50924.0 54145.0 61232.0 50827.0 51449.0 51642.0 55822.0 True False 64146.04760111125 69015.73026427471 44450.63408615968 39184.2585679571 46627.90136073156 57403.15336026315 55350.50453505408 43498.73923040511 54371.690690767435 53867.68877089444 1.190807496381214 1.2812083057397665 0.8251817573836034 0.727416740202319 0.8656005561895453 1.0656323794474543 1.0275269980575226 0.8075107772937933 1.0093562937518366 1.0 15.717132546261631 -5.25719875468938 24.973171001264685 0.9099415676594402 1.2360079312063033 0.5911321722503489 0.10635021326419167 247.42808874125527 1457097.5719216191 0.029455674845357886 0.0723604710137467 5.530969267067875e-06 5.25719875468938 0.326066363546863 EEKS(ph)VEYEGDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EEKSVEYEGDLK 12 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0;H7C3N7 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 EEKS(0.999)VEY(0.001)EGDLK;EEKS(1)VEYEGDLK 78.32600000000001 0.0078308 13139300.0 79233.0 77842.0 69271.0 86554.0 93850.0 65082.0 80518.0 59413.0 71386.0 60131.0 True False 92645.5819769168 85569.63932014386 70922.68335173039 81704.65999185403 75460.76620786217 61668.98534968695 72890.75214016176 57853.47170327702 72429.88520095624 71032.27430326586 1.3042744708042837 1.2046585887819392 0.9984571667933989 1.1502469939653541 1.0623447854941157 0.8681826107157543 1.0261638509413522 0.8144673990906847 1.0196757165865675 1.0 16.11618705765538 -3.5959945041404886 0.4322151880557725 0.9351022583203619 2.2222126553133825 0.6365948671489211 0.0838972346418498 8.527969263667952 0.5605076712374683 0.05710107724423382 6.9904507621525065 0.00025351607119530824 3.5959945041404886 1.2871103969930207 EEKS(ph)VEYEGDLK ddPTM_PC-9_Lapatinib_30min_R1 2 EEKSVEYEGDLK 12 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0;H7C3N7 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 EEKS(1)VEYEGDLK;EEKS(0.999)VEY(0.001)EGDLK 116.58 0.0032339 22823000.0 83611.0 73625.0 71548.0 78527.0 64655.0 67756.0 74463.0 63920.0 70402.0 60555.0 True False 82418.69180762029 73454.52583600639 65665.59962326677 84302.13753839285 60852.12001662077 64858.23382695035 78318.32978974275 66889.95655143242 62472.585394073845 71021.85106553453 1.160469497360319 1.0342524833410374 0.9245830492741544 1.186988740417426 0.8568084202771656 0.9132151986168767 1.1027356878867531 0.9418222075021748 0.879624854277989 1.0 16.115975341827024 -1.522878746401493 0.6933133445729095 0.9678562078375288 22.92431312359831 0.2545466279101637 0.09615967099681327 409.8403551115048 2.23502588716305 0.03826335120976162 13932.901413091151 0.029999999922553325 1.522878746401493 21.956456915760782 EELDFQK ddPTM_PC-9_Lapatinib_30min_R1 1 EELDFQK 7 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 126.67 0.020929 7223400.0 40705.0 26784.0 33519.0 34464.0 32896.0 26190.0 38170.0 31414.0 28628.0 28695.0 False True 40124.53923561723 26721.983293604044 30763.197207081725 36998.59752853372 30961.121956024403 25069.914751871886 40146.25583275562 32873.60912244522 25403.613173795417 33654.89251631592 1.1922349541352664 0.793999959460551 0.9140780108617996 1.0993527170112567 0.9199590205499668 0.7449114490476524 1.1928802272446029 0.9767854437956699 0.7548267510133845 1.0 15.038528628692625 -4.738425539684382 24.479135898251847 0.9386983775971227 1.1922363102253444 0.24168126391048728 0.1374350315226234 2335.5330475357428 2484070.362112966 0.034127539191718785 1.834149264807763 1.8263098452716897e-05 4.738425539684382 0.25353793262822166 EELDQYK ddPTM_PC-9_Lapatinib_30min_R1 2 EELDQYK 7 0 A0A3B3IRX4;Q5SXQ8;A0A1B0GUT5;A0A6E2AE84;Q8IYJ2 A0A3B3IRX4 C10orf67 Uncharacterized protein C10orf67 0 ; 117.93 0.032913 10143200.0 38166.0 54620.0 53062.0 43163.0 54996.0 51206.0 50065.0 51698.0 57128.0 49750.0 False True 37621.74584121281 54493.53074584282 48699.44718524328 46337.35100754703 51761.2434062961 49016.03874701612 52657.120730073635 54100.077812827854 50693.64305549059 58349.22121229195 0.6447686028976055 0.9339204468141747 0.8346203457979345 0.7941382943048694 0.8870939891035252 0.8400461519217384 0.9024477042888241 0.9271773759583792 0.8687972521698606 1.0 15.83242577994373 -1.5228787454178074 0.0926459778650806 1.0742044133467492 0.2275178458730242 0.4740622478930826 0.06638237284612167 140.72772392645624 0.9375795515978763 1.080786840713817 15.1326999811468 0.029999999990503918 1.5228787454178074 -0.846686567473725 EELEALRR ddPTM_PC-9_AZD4547_30min_R2 2 EELEALRR 8 1 K7EQ71;K7EKI8;O60437 K7EQ71 PPL Periplakin 0 ; 125.31 0.0021676 6115400.0 29297.0 32510.0 41253.0 42483.0 43387.0 40653.0 39877.0 49526.0 35476.0 38947.0 False True 38612.836584544 43018.221732300015 40705.95826576863 32689.200705807103 37363.463964134455 38110.9614834527 43425.97574801485 41872.89469426118 37351.18893431056 37583.477384544174 1.0273886098794875 1.1446046168679118 1.0830812127700709 0.8697758424889711 0.9941460068168094 1.0140349998354716 1.1554539060793065 1.1141304000646035 0.9938193997363016 1.0 15.19781093681678 -9.865684843412543 15.471420133910653 0.9999818376981365 1.046015646133528 0.025442039433671737 0.08096610301861037 0.0 0.0 0.08485585131556221 0.020580566936810023 1.362433007203455e-10 9.865684843412543 0.0460338084353914 EELEALRR ddPTM_PC-9_Lapatinib_30min_R1 1 EELEALRR 8 1 K7EQ71;K7EKI8;O60437 K7EQ71 PPL Periplakin 0 136.75 4.8696e-08 0.0 14888.0 14429.0 14499.0 14236.0 14201.0 15718.0 13376.0 11825.0 16399.0 12840.0 False True 14675.694389875172 14395.590537015112 13306.948187758515 15282.962929903842 13365.725100240214 15045.777780447585 14068.543830729353 12374.432669284866 14551.97193087435 15059.376891775448 0.974522020090365 0.9559220570989988 0.8836320575140126 1.0148469647672145 0.887535068435653 0.9990969671968771 0.9342049097936297 0.821709474317165 0.9663063774452572 1.0 13.87837445674766 -7.5278245203159155 24.98959516839528 0.9119962113405538 0.9509126484758176 0.007622894119382551 0.05863546144452215 362.095735116406 1829522.7550725176 0.025741634249062856 0.01493124892178562 2.9660295921732648e-08 7.5278245203159155 0.038916437135263826 EELEEVIK ddPTM_PC-9_Lapatinib_30min_R1 1 EELEEVIK 8 0 P28066;P28066-2 P28066 PSMA5 Proteasome subunit alpha type-5 0 109.21 0.017422999999999998 1076200.0 8740.8 8093.9 6193.8 8752.1 9195.6 8663.1 8807.7 7142.6 8034.4 10280.0 False True 8616.154589133594 8075.159071837729 5684.5696727594095 9395.758630149721 8654.732887245196 8292.59940767245 9263.71960959292 7474.471271343261 7129.481266017247 12056.884302761026 0.7146253022566116 0.6697550435968369 0.4714791591271755 0.7792857917694452 0.7178249927523368 0.6877895814073164 0.7683344533273433 0.6199338969879314 0.5913203682633495 1.0 13.557569518819234 -10.632076390071104 4.3945280571917715 1.0000375312204404 0.6698661378571629 0.5703271985736056 0.08620523563508146 25360975.356509432 20452698.758990005 8625.913468050328 0.021341235387485665 2.3330476556127952e-11 10.632076390071104 -0.3301713933632775 EELEEVIKDI ddPTM_PC-9_AZD4547_30min_R2 2 EELEEVIKDI 10 1 P28066;P28066-2 P28066 PSMA5 Proteasome subunit alpha type-5 0 ; 107.21 0.019622999999999998 5136200.0 22452.9 24550.8 31168.0 32174.0 31365.0 32267.0 28455.0 33154.0 26681.8 29113.0 False True 29592.455150667567 32486.36598293913 30754.691955190567 24756.7813833448 27010.511149309175 30249.339389136578 30987.43987536081 28030.811103128373 28092.145476025686 28093.762731307554 1.0533460908634313 1.1563551060654642 1.0947160139897418 0.8812198501184024 0.961441562941969 1.0767279441506374 1.1030006970489772 0.9977592311581308 0.9999424336534292 1.0 14.777962243965726 -5.553259746577241 24.998844199577412 1.0067361416291691 1.110022009369364 0.3515019315165179 0.06123943657986077 222.5072821359071 183087.953674312 0.01800230196749888 0.031181332692030266 2.7973077813366563e-06 5.553259746577241 0.10328586774019488 EELEEVIKDI ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EELEEVIKDI 10 1 P28066;P28066-2 P28066 PSMA5 Proteasome subunit alpha type-5 0 ; 110.14 0.015864 3212400.0 28094.5 29717.0 29509.0 29622.0 37275.0 31708.0 31128.0 27684.8 27240.0 24392.0 False True 32850.343958331665 32667.107367188913 30212.606473505704 27962.375375819745 29971.23133082639 30045.176661256148 28179.330492796016 26958.103334470292 27638.333466983015 28814.076513034233 1.14007970873096 1.1337204353022294 1.0485363450686624 0.9704414910944928 1.0401593581272235 1.0427256500018323 0.9779709747091465 0.9355879693827988 0.9591955325891023 1.0 14.814486161848546 -4.120263634050223 0.45059703291345393 0.9689898936105759 1.439332129170679 0.745487176132704 0.03357787395639622 4.704200418282724 0.4725389787527768 0.025036959839474234 1.3347175191201894 7.581172279625653e-05 4.120263634050223 0.47034223556010324 EELEEVIKDI ddPTM_PC-9_Lapatinib_30min_R1 1 EELEEVIKDI 10 1 P28066;P28066-2 P28066 PSMA5 Proteasome subunit alpha type-5 0 117.31 0.008607 6346000.0 12888.0 11223.0 13377.0 10367.0 10857.0 12158.0 12089.0 11407.0 11003.0 11052.0 False True 12704.214756630257 11197.013833039067 12277.194696713264 11129.423763298191 10218.412605683272 11638.030681682252 12714.909268068708 11937.010863300839 9763.726273273396 12962.32347413569 0.9800877737683025 0.8638122521306443 0.947144601136556 0.8585979038021412 0.7883164330895254 0.8978352303045161 0.9809128196375705 0.9209005536020834 0.7532388998589181 1.0 13.662036721550486 -11.025284113054413 4.986105503508194 1.0003662657251646 0.8891193881086398 0.18038324706759112 0.07165959109350314 0.00029482578039880794 2.9422439057797433e-05 0.07011188338811333 0.016948941367788097 9.434434788392912e-12 11.025284113054413 -0.11124687761652485 EELEFEVPFR ddPTM_PC-9_Lapatinib_30min_R1 2 EELEFEVPFR 10 0 Q9Y5B9 Q9Y5B9 SUPT16H FACT complex subunit SPT16 0 ; 120.12 0.0033756999999999997 3590900.0 22623.1 20765.3 17586.2 17285.1 17107.9 18639.8 17201.1 16584.9 17558.7 17485.0 False True 22300.490445431573 20717.219223666227 16140.330520695152 18556.30391540326 16101.646957425512 17842.619205496052 18091.688792371297 17355.49500015413 15581.054304691968 20507.258952702006 1.087443743547857 1.010238339090001 0.7870545038672039 0.9048651483946034 0.7851681687232014 0.8700635831755142 0.8822090184796522 0.8463098379058306 0.7597823941575104 1.0 14.323847050323073 -5.096019146569165 4.238064093521969 0.8502565594268379 1.073273078851473 0.5879027324607637 0.06626806015454441 0.13101569163168097 3.996623393794713 0.01588044187039919 0.04950285268970094 8.016427209028398e-06 5.096019146569165 0.22301651942463518 EELFIVSK ddPTM_PC-9_Lapatinib_30min_R1 2 EELFIVSK 8 0 P15121;E9PCX2;E9PEF9 P15121 AKR1B1 Aldose reductase 0 ; 134.91 0.015811000000000002 11132900.0 95672.0 81898.0 104590.0 102290.0 90692.0 86567.0 91907.0 84685.0 85882.0 85113.0 False True 94307.69973590372 81708.3702127983 95991.01392907553 109812.74782943708 85357.67486733236 82864.73120753323 96665.49475559528 88619.77425779185 76209.06478244712 99824.66864405634 0.9447334112590505 0.8185188222777366 0.961596118804557 1.1000562217841676 0.8550759649570311 0.8301027424694295 0.9683527736042312 0.8877542541491659 0.7634291785549011 1.0 16.607108757563594 EELMS(ph)SDLEETAGSTSIPK ddPTM_PC-9_AZD4547_30min_R2 2 EELMSSDLEETAGSTSIPK 19 0 O00567 O00567 NOP56 Nucleolar protein 56 1 EELMS(0.534)S(0.465)DLEETAGSTSIPK;EELMS(0.494)S(0.494)DLEET(0.011)AGS(0.001)TSIPK 69.979 0.0064736 5193900.0 25966.6 35189.2 41274.3 36214.4 35168.3 40532.2 35560.0 47379.9 36060.5 38043.9 True False 34223.43866116733 46563.42073768843 40726.975813851444 27865.729586902547 30285.78859404588 37997.715126549134 38724.771111152026 40058.425136789265 37966.58441103016 36711.99464066193 0.9322140895951676 1.2683435262358405 1.1093642884972137 0.759036109578167 0.8249562272626171 1.035021809587626 1.054826126724827 1.0911536005842857 1.034173838350332 1.0 15.163963880802907 -5.563749804285773 24.99978430292529 0.9719946032038587 1.1224237206240675 0.18789519546933398 0.12414782062787401 225.11218694403811 137694.3894306593 0.03605239567955868 0.06244465761908464 2.730550391452685e-06 5.563749804285773 0.1504291174202088 EELMS(ph)SDLEETAGSTSIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EELMSSDLEETAGSTSIPK 19 0 O00567 O00567 NOP56 Nucleolar protein 56 1 EELMS(0.485)S(0.485)DLEET(0.03)AGSTSIPK;EELMS(0.732)S(0.268)DLEETAGSTSIPK;EELMS(0.5)S(0.5)DLEETAGSTSIPK 143.83 2.5246999999999997e-05 30054900.0 134128.1 188596.0 157024.0 145079.0 166979.0 114149.0 159129.0 111422.0 117789.0 105763.9 True False 156833.3381792702 207318.56449245752 160768.04767683597 136950.69398246432 134260.6636187809 108162.82549217014 144055.1491258075 108497.29056136745 119511.4412901052 124938.05784342832 1.2552887477714187 1.6593707959849031 1.2867820298464188 1.096148734391967 1.0746178221133837 0.8657316061989629 1.153012553679493 0.8684086533291213 0.9565655441825122 1.0 16.930853482996717 -5.744053548726159 2.069924195194042 0.9847218128144487 1.463625980619393 0.7001945750206903 0.12362813191253127 0.1595247849511023 1.3932996944357132 0.03563846915255953 0.07060174646415297 1.8027954415782203e-06 5.744053548726159 0.47890416780494427 EELMS(ph)SDLEETAGSTSIPK ddPTM_PC-9_Lapatinib_30min_R1 3 EELMSSDLEETAGSTSIPK 19 0 O00567 O00567 NOP56 Nucleolar protein 56 1 EELMS(0.57)S(0.43)DLEET(0.001)AGSTSIPK;EELMS(0.5)S(0.5)DLEETAGSTSIPK;EELMS(0.478)S(0.478)DLEET(0.021)AGS(0.002)T(0.009)S(0.013)IPK 169.62 7.910199999999999e-28 13685000.0 102540.0 138771.7 122285.7 106813.1 123513.5 138063.3 138215.2 133987.5 131480.0 105489.1 True False 101077.76079646702 138450.38265475817 112231.84178245267 114668.49169205641 116248.67876688417 132158.65450027154 145371.30676383254 140213.04839541682 116671.33785422034 123722.75037960989 0.81696988214647 1.1190373818069879 0.9071237216930559 0.9268181586670768 0.9395901595317471 1.0681839362185075 1.174976358978441 1.1332842825204814 0.9430063387392037 1.0 16.916751284710536 -6.784873007191522 6.883286397475774 1.079781343090907 0.9488493740123396 0.29411271045210907 0.09260786977534924 0.2075360816276396 36.45250263222594 0.03184026712758659 0.02881726574432234 1.6410695710682574e-07 6.784873007191522 -0.1309319690785673 EELMS(ph)SDLEETAGSTSIPKR ddPTM_PC-9_Lapatinib_30min_R1 1 EELMSSDLEETAGSTSIPKR 20 1 O00567 O00567 NOP56 Nucleolar protein 56 1 EELMS(0.5)S(0.5)DLEETAGSTSIPKR 54.626000000000005 0.011025 3500700.0 12870.0 8959.4 10762.0 6996.1 10349.0 9451.2 5988.9 8277.0 10865.0 8008.2 True False 12686.47143993106 8938.6550597639 9877.189902521355 7510.616532305445 9740.292166916834 9046.99420782327 6298.975938087242 8661.57963667407 9641.269286477827 9392.406699744246 1.3507157265960927 0.9516895238370905 1.0516143751303177 0.7996477124984332 1.0370390122887312 0.9632242828741242 0.6706455692829786 0.9221895850091248 1.026496146801262 1.0 13.19727916446873 -2.366188424132306 1.2346384934994803 0.9162127278963199 199.95872801244295 0.5407025941641713 0.11359654733570132 525.1576442062833 2.3331941780719396 0.03353105413958447 294323.2936113369 0.004303398616124915 2.366188424132306 199.04251528454662 EELMSS(ph)DLEETAGSTSIPK ddPTM_PC-9_AZD4547_30min_R2 3 EELMSSDLEETAGSTSIPK 19 0 O00567 O00567 NOP56 Nucleolar protein 56 1 EELMS(0.014)S(0.986)DLEETAGSTSIPK;EELMS(0.4)S(0.596)DLEET(0.004)AGSTSIPK;EELMS(0.03)S(0.97)DLEETAGSTSIPK 185.33 6.5945e-11 39025000.0 123931.8 157465.1 139568.0 133939.6 125298.5 153290.9 155807.0 179258.1 150230.8 138324.6 True False 163339.53445842225 208362.61417713927 137717.2371278888 103061.89456619164 107902.96608454386 143705.59579031818 169673.52116184682 151557.87958634557 158171.6933857433 133481.89785673143 1.2236830392817577 1.5609803091111176 1.0317296902363737 0.7721039048816182 0.8083715306502316 1.0765923926595653 1.2711350668984382 1.1354189745565006 1.1849673695493292 1.0 17.02628457857365 -5.279911135971098 23.793320857741495 1.0323063374375527 1.3923316377046993 0.4317769972654385 0.16392648056152803 385.20507098883064 496179.6371626083 0.047903409708404544 0.10007019972112118 5.249148557588001e-06 5.279911135971098 0.3600253002671465 EELMSS(ph)DLEETAGSTSIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EELMSSDLEETAGSTSIPK 19 0 O00567 O00567 NOP56 Nucleolar protein 56 1 EELMS(0.026)S(0.973)DLEET(0.001)AGSTSIPK 147.17 3.5367e-14 0.0 8056.0 12610.0 8802.3 8560.4 9660.7 7751.6 10527.0 7855.5 7249.0 6066.6 True False 9419.721686747222 13861.83746341328 9012.18021490864 8080.788541191255 7767.75518491522 7345.09245008809 9529.806351120014 7649.3014485902495 7355.00291123935 7166.426556820825 1.314423808303982 1.9342746839734137 1.257555651125884 1.127589667893849 1.0839091314655371 1.0249309599213314 1.3297849738025689 1.0673801493590744 1.0263138612980054 1.0 12.807038202212295 -5.463037329036646 6.0136633391947125 1.1092768130951562 1.6244257390159607 0.6180024295867379 0.16431229635843606 0.12869493223957634 9.61742333803034 0.04072797555971535 0.08484203049024808 3.4432033402816607e-06 5.463037329036646 0.5151489259208044 EELMSS(ph)DLEETAGSTSIPK ddPTM_PC-9_Lapatinib_30min_R1 2 EELMSSDLEETAGSTSIPK 19 0 O00567 O00567 NOP56 Nucleolar protein 56 1 EELMS(0.099)S(0.901)DLEETAGSTSIPK;EELMS(0.233)S(0.767)DLEETAGSTSIPK 214.5 1.4266999999999995e-73 13503000.0 85573.0 101388.0 92903.0 80114.0 93777.0 95617.0 101040.0 95210.0 95343.0 78586.0 True False 84352.71332783373 101153.24231526017 85264.87395595055 86005.85081246952 88261.22123267573 91527.68380411365 106271.35680748294 99633.80418119338 84604.46733370039 92169.48539073717 0.9151913235734631 1.0974699694420322 0.9250878812492478 0.9331271672816882 0.9575969840615578 0.9930367237714011 1.152999350674068 1.080984707235941 0.9179227482396571 1.0 16.492001575301018 -7.015487398597517 24.274296215948336 1.04876723091701 0.9695869214456755 0.1699374383486748 0.07359824312524264 797.9156906440287 1250618.0347535938 0.027754517643375973 0.022219443492641402 9.64967310699324e-08 7.015487398597517 -0.07918030947133448 EELMSS(ph)DLEETAGSTSIPKR ddPTM_PC-9_Lapatinib_30min_R1 1 EELMSSDLEETAGSTSIPKR 20 1 O00567 O00567 NOP56 Nucleolar protein 56 1 EELMS(0.46)S(0.539)DLEET(0.001)AGSTSIPKR 60.272 0.0051752 10075000.0 37721.0 27356.0 30244.0 27075.0 25034.0 28122.0 18591.0 18349.0 29129.0 22573.0 True False 37183.09162281579 27292.658862747645 27757.45506521613 29066.185819552302 23561.549338737674 26919.28761558386 19553.551013538385 19201.561526317808 25848.185278031513 26474.71297336816 1.404475722181372 1.0308953638214051 1.0484515957977836 1.0978848325491193 0.8899642977220965 1.0167924253857978 0.7385746177194814 0.7252793088118964 0.9763348635368816 1.0 14.692327422817371 -1.5228787453576658 0.45102291375572023 0.8640757812126981 12.056711205183758 0.6222249644502442 0.1121163400356674 58.32011808401046 0.7009115411042729 0.07148678118648243 601.5212519950826 0.02999999999465836 1.5228787453576658 11.19263542397106 EELQANGSAPAADKEEPAAAGS(ph)GAASPSAAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EELQANGSAPAADKEEPAAAGSGAASPSAAEK 32 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 EELQANGSAPAADKEEPAAAGS(0.904)GAAS(0.084)PS(0.012)AAEK;EELQANGSAPAADKEEPAAAGS(0.539)GAAS(0.442)PS(0.019)AAEK;EELQANGSAPAADKEEPAAAGS(0.729)GAAS(0.254)PS(0.017)AAEK 123.07 2.0444e-18 58340000.0 184663.0 325854.0 216792.0 171671.0 202371.0 117173.0 194151.0 90602.0 114872.0 121606.0 True False 215922.79863949862 358202.6316259365 221961.14346823827 162052.83043489148 162717.8552823785 111028.24160872221 175759.61174848472 88223.79350075393 116551.785683527 143652.20516743386 1.5030942155592373 2.4935407793318127 1.5451286891804508 1.1280914918501306 1.1327209011008406 0.772896186865445 1.223507926965883 0.6141485499503796 0.8113469998436853 1.0 17.132220613911514 -5.681879851991503 2.3417971004432623 0.9270349949723484 2.0094664897603023 0.6919354181791095 0.2833471660336047 0.14945010798712424 1.6605236198485187 0.07974044150648947 0.15997563340425214 2.080272116892526e-06 5.681879851991503 1.0824314947879539 EELQANGSAPAADKEEPAAAGS(ph)GAASPSAAEK ddPTM_PC-9_Lapatinib_30min_R1 3 EELQANGSAPAADKEEPAAAGSGAASPSAAEK 32 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 EELQANGSAPAADKEEPAAAGS(0.865)GAAS(0.132)PS(0.003)AAEK;EELQANGSAPAADKEEPAAAGS(0.697)GAAS(0.294)PS(0.009)AAEK;EELQANGSAPAADKEEPAAAGS(0.724)GAAS(0.258)PS(0.019)AAEK 110.41 3.0729e-16 70329000.0 162557.0 260372.0 191000.0 183176.0 254329.0 225326.0 259630.0 252333.0 202259.0 196640.0 True False 160238.90737069695 259769.12463120802 175296.71728132138 196647.3740972232 239369.86825005262 215689.33224056073 273072.37102065375 264057.3123669059 179478.4615383083 230628.96199366965 0.6947909143132475 1.1263508380978544 0.7600811093540496 0.8526568926873148 1.0379002974336886 0.9352222304433777 1.1840333003282957 1.14494428663367 0.7782130222796331 1.0 17.815214169998015 -6.262652747314089 24.41027833311117 1.0252569661578386 0.8705765105777411 0.20461970598995693 0.14775694357287392 130.67434652920247 2628884.251224152 0.04405973535154721 0.052828750987751534 5.461944120438289e-07 6.262652747314089 -0.15468045558009746 EELQANGSAPAADKEEPAAAGSGAAS(ph)PSAAEK ddPTM_PC-9_AZD4547_30min_R2 4 EELQANGSAPAADKEEPAAAGSGAASPSAAEK 32 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 EELQANGS(0.001)APAADKEEPAAAGS(0.358)GAAS(0.61)PS(0.031)AAEK;EELQANGSAPAADKEEPAAAGS(0.36)GAAS(0.608)PS(0.032)AAEK;EELQANGSAPAADKEEPAAAGS(0.303)GAAS(0.692)PS(0.005)AAEK;EELQANGSAPAADKEEPAAAGS(0.321)GAAS(0.523)PS(0.156)AAEK 111.01 2.5303e-16 97219000.0 254911.0 366957.0 287807.0 172475.0 204514.0 342545.0 346160.0 387510.0 376560.0 251009.0 True False 335967.39552181715 485568.6740147531 283990.4911302468 132713.55346218668 176120.76126860594 321125.606999466 376967.56939922314 327629.2335939335 396464.19283752405 242221.25131119395 1.3870269173458392 2.0046493500725844 1.1724425069763584 0.5479021875404435 0.7271069747812287 1.3257532328858281 1.5562943687171105 1.3526031750740632 1.6367853385752944 1.0 17.885965920048285 -6.990572472385807 24.95374281720279 1.4194071782822648 1.1647619307489168 0.06262588422839033 0.3966466840222979 616.455189717159 1631688.3114702327 0.15766495653610713 0.13886867269692618 1.0219450104870154e-07 6.990572472385807 -0.25464524753334805 EELQANGSAPAADKEEPAAAGSGAAS(ph)PSAAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EELQANGSAPAADKEEPAAAGSGAASPSAAEK 32 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 EELQANGSAPAADKEEPAAAGS(0.354)GAAS(0.616)PS(0.03)AAEK 103.68 6.55e-15 19230000.0 51163.0 86646.0 63280.0 46181.0 57694.0 34637.0 53878.0 26005.0 35341.0 34769.0 True False 59823.885384688234 95247.64225653493 64788.83519073637 43593.628290822104 46389.27485984438 32820.57474504633 48774.28579705936 25322.396304575064 35857.7952663967 41072.344468747455 1.4565490759897843 2.3190213144275282 1.5774321146930177 1.0613864110920945 1.1294528096671632 0.7990918261318144 1.1875213462472887 0.6165315526081849 0.8730398941234392 1.0 15.32587968033364 -5.696210335991465 2.7438225781205907 0.9328267093514071 1.9042037676261785 0.7109907349349577 0.24827692221968015 0.1288985025267561 1.962572405098298 0.0686909104713486 0.12938471361472748 2.0127492060785075e-06 5.696210335991465 0.9713770582747714 EELQANGSAPAADKEEPAAAGSGAAS(ph)PSAAEK ddPTM_PC-9_Lapatinib_30min_R1 1 EELQANGSAPAADKEEPAAAGSGAASPSAAEK 32 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 EELQANGSAPAADKEEPAAAGS(0.337)GAAS(0.6)PS(0.062)AAEK 92.865 1.8994e-10 26599000.0 72853.0 120150.0 79162.0 76248.0 102540.0 113870.0 113770.0 103760.0 77553.0 84181.0 True False 71814.10286039599 119871.80005699408 72653.60593415669 81855.53227587162 96508.79880139644 109000.04554393476 119660.45391911478 108581.06839450309 68818.16447070542 98731.57368586803 0.7273671448698393 1.214118195243068 0.7358700284198547 0.8290714836199156 0.9774866863609026 1.1040039318195989 1.2119775817595664 1.0997603334063424 0.6970228661569052 1.0 16.591223902080827 -6.500612475908632 6.466708022854478 1.0409240622951177 0.8916481809948316 0.12488737905882585 0.1777143278510391 0.3749456060488346 61.1313038640586 0.05714695429491637 0.06219617935311103 3.157821113103501e-07 6.500612475908632 -0.14927588130028613 EELS(ph)HSPEPCTK ddPTM_PC-9_Lapatinib_30min_R1 1 EELSHSPEPCTK 12 0 P41229-4;P41229-3;P41229-2;P41229-5;P41229 P41229-4 KDM5C Lysine-specific demethylase 5C 1 EELS(0.885)HS(0.115)PEPCTK 175.48 0.0010445 8098200.0 31402.0 37821.0 39928.0 37439.0 43147.0 35966.0 36015.0 36631.0 43227.0 32581.0 True False 30954.20172157849 37733.42779821532 36645.27396653716 40192.38895284282 40609.178290265794 34427.81802084093 37879.68047725159 38333.0099880401 38358.32005951005 38212.58243854641 0.8100525990715004 0.9874608150050663 0.9589844922276636 1.0518103302094368 1.0627174532256123 0.9009550211951222 0.991288158505639 1.0031515155953505 1.00381386474463 1.0 15.221760139087047 -4.756888128467783 4.9599690008699655 0.9960461235608772 0.7971013669867559 0.6313314807552428 0.0425756104566578 0.1250173173656868 7.9124584298160014 0.011045334208061195 0.08745146173987908 1.7502974962069407e-05 4.756888128467783 -0.19894475657412125 EELSHS(ph)PEPCTK ddPTM_PC-9_AZD4547_30min_R2 2 EELSHSPEPCTK 12 0 P41229-4;P41229-3;P41229-2;P41229-5;P41229 P41229-4 KDM5C Lysine-specific demethylase 5C 1 EELS(0.01)HS(0.854)PEPCT(0.135)K;EELS(0.302)HS(0.67)PEPCT(0.028)K 101.56 0.0037954 18050400.0 80977.0 91084.0 122784.0 142090.0 117444.0 121796.0 110689.0 144867.0 116693.0 116347.0 True False 106726.00157376575 120525.12175530041 121155.8039343596 109333.34576861632 101138.92783100497 114180.07686612548 120540.10656699425 122481.13386248678 122861.15374651886 112273.72694327049 0.950587501452518 1.0734935504207423 1.0791109125252165 0.9738106032933254 0.9008245346848448 1.0169794837559658 1.0736270171907678 1.09091536548327 1.094300127834876 1.0 16.776660838121494 -7.199060038520981 4.812881404558539 1.0724092939313283 0.9996860565031257 0.24995169265161266 0.05549277465267606 0.32024313096786944 15.134182361216977 0.02368187410005713 0.017906348665648653 6.323244303994026e-08 7.199060038520981 -0.07272323742820264 EELSHS(ph)PEPCTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EELSHSPEPCTK 12 0 P41229-4;P41229-3;P41229-2;P41229-5;P41229 P41229-4 KDM5C Lysine-specific demethylase 5C 1 EELS(0.045)HS(0.896)PEPCT(0.06)K;EELS(0.047)HS(0.811)PEPCT(0.142)K 121.56 0.00044126 24539000.0 45494.0 52388.0 59236.0 61287.0 68720.0 51304.0 62114.0 49284.0 54098.0 42350.0 True False 53195.23565254201 57588.73441976956 60648.41089378097 57853.28808513484 55254.809310647586 48613.52792446971 56230.11225358299 47990.3472207144 54889.080906639036 50027.71975758447 1.0633152162502335 1.151136503898697 1.2122961267805206 1.1564246454859453 1.1044838657126814 0.9717318350712885 1.1239791164988728 0.9592751269347791 1.0971733505466748 1.0 15.610440075945721 -6.551605798726235 6.0990470191973145 1.0336281526877527 1.1487620083378125 0.46721273430585064 0.05841584502600221 0.15276831772579635 17.566584544140916 0.01867146093589389 0.018975856305638472 2.8079812355307524e-07 6.551605798726235 0.11513385565005985 EELSHSPEPCT(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EELSHSPEPCTK 12 0 P41229-4;P41229-3;P41229-2;P41229-5;P41229 P41229-4 KDM5C Lysine-specific demethylase 5C 1 EELSHS(0.01)PEPCT(0.99)K 136.24 0.00015359 9337300.0 21297.0 19112.0 24533.0 25644.0 34603.0 22246.0 23463.0 20703.0 17151.0 20014.0 True False 24902.161465076413 21009.313053192276 25117.95976192062 24207.24981896974 27822.79054971391 21079.380598155185 21240.414782590367 20159.568186641704 17401.800928495806 23642.379769263174 1.0532848938265955 0.888629370572328 1.0624124985326482 1.023892266989169 1.1768185276291678 0.8915930123734804 0.8984042634407076 0.8526877743860041 0.736042695292435 1.0 14.529087639621446 -6.968511399512214 22.82072583718491 0.8645777719549326 1.0329232272178308 0.46267706094016436 0.08890354139999104 69.50603771373798 50372.38589262308 0.03142929251629549 0.02771750808902703 1.0751983778423316e-07 6.968511399512214 0.16834545526289824 EELSHSPEPCT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 EELSHSPEPCTK 12 0 P41229-4;P41229-3;P41229-2;P41229-5;P41229 P41229-4 KDM5C Lysine-specific demethylase 5C 1 EELSHS(0.119)PEPCT(0.881)K 87.667 0.020669999999999997 10478000.0 17358.0 21588.0 24414.0 22370.0 22660.0 26335.0 22477.0 20796.0 27517.0 18311.0 True False 17110.47173693266 21538.01431236277 22406.77516076533 24015.164424132417 21327.1833512741 25208.713439883395 23640.74907919435 21762.258079530504 24417.745693144047 21476.031952126174 0.796724077104881 1.0028861178999346 1.043338695468229 1.1182309878131311 0.9930690827251569 1.1738068511016384 1.1007968851924652 1.0133277007615922 1.1369765954704978 1.0 14.390439836009582 -4.433360656916173 1.388672338266813 1.0788731584542453 0.4179702810443797 0.6761081785931371 0.05752491669041272 1.6038555363785851 1.4823993975864918 0.015742403719838458 1.8751769436908412 3.686713108130255e-05 4.433360656916173 -0.6609028774098655 EELSNVLAAMR ddPTM_PC-9_Lapatinib_30min_R1 1 EELSNVLAAMR 11 0 Q9Y3U8 Q9Y3U8 RPL36 60S ribosomal protein L36 0 106.62 0.011111 2743400.0 12943.0 14199.0 13205.0 13080.0 13976.0 15146.0 16908.0 11912.0 13273.0 12447.0 False True 12758.430446544491 14166.123087883956 12119.335872774072 14041.946833600889 13153.959157873205 14498.240887050457 17783.41350852061 12465.475006893988 11778.054969113686 14598.447365415028 0.8739580400015898 0.9703855987757105 0.8301797834669609 0.9618794712968903 0.9010519289219798 0.9931358126068962 1.218171567385381 0.8538904648466772 0.8068018929887645 1.0 13.8335273173308 -6.759484909481458 24.95986201567414 0.9805038325228708 0.9097116219262655 0.08559481420456294 0.10830991175310112 143.69699382024803 1835107.85882227 0.03875732598171342 0.03692629628080383 1.739863152366191e-07 6.759484909481458 -0.07079221059660523 EELSSGDSLS(ph)PDPWKR ddPTM_PC-9_Lapatinib_30min_R1 1 EELSSGDSLSPDPWKR 16 1 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 EELS(0.001)S(0.001)GDS(0.003)LS(0.995)PDPWKR 66.60600000000001 0.012114 4039200.0 36845.0 43726.0 33593.0 36795.0 39715.0 32276.0 35527.0 34315.0 38807.0 38752.0 True False 36319.583543454544 43624.75513351746 30831.113212729964 39501.027044521776 37379.041782694214 30895.630719030825 37366.41422505394 35909.40017306641 34436.14700417349 45450.23156620577 0.7991066776095314 0.9598357066667701 0.678348869748207 0.8691050778692294 0.822416971148881 0.6797683896071296 0.8221391385129376 0.7900817869488395 0.7576671409035958 1.0 15.472000024432322 -11.26568881136484 2.5341761455044836 1.0448481970627694 0.798738387259452 0.37123493195497614 0.07900728232797437 19946852.09217727 14717097.714038072 5613393.293470344 0.019430430413755542 5.423893939771938e-12 11.26568881136484 -0.24610980980331743 EELYQNLTR ddPTM_PC-9_Lapatinib_30min_R1 1 EELYQNLTR 9 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 99.01299999999999 0.010231 0.0 10193.0 14289.0 14264.0 10973.0 13630.0 15953.0 10451.0 17054.0 13654.0 11709.0 False True 10047.645950832733 14255.914698413548 13091.26898063228 11779.991024854933 12828.31019761103 15270.727378259333 10992.101642864263 17846.391098687884 12116.14273700581 13732.885048738215 0.7316485876910414 1.0380859264327265 0.9532788583149986 0.8577943369545123 0.9341307490802672 1.1119824657428714 0.8004218781307154 1.2995369170681015 0.8822722023817601 1.0 13.745347122898101 -6.560472180368633 14.187020282492574 1.0238355757055242 0.9078571757648874 0.1411590546093182 0.14383376883013219 3.984098430469502 1500.6360655791298 0.04482352221901693 0.04483293741554638 2.751235835448214e-07 6.560472180368633 -0.11597839994063674 EENISAPLISS(ph)SPVK ddPTM_PC-9_AZD4547_30min_R2 1 EENISAPLISSSPVK 15 0 A2A2Y4-4;A2A2Y4-3;A2A2Y4-5;A2A2Y4-2;A2A2Y4 A2A2Y4-4 FRMD3 FERM domain-containing protein 3 1 EENISAPLIS(0.024)S(0.669)S(0.307)PVK 142.19 1.1687000000000001e-06 0.0 22174.0 18879.0 26599.0 21359.0 22200.0 15226.0 24678.0 30478.0 17506.0 19331.0 True False 29224.87075214797 24981.26755103327 26246.279880522157 16435.01254326045 19117.91319989362 14273.915813028592 26874.294192379348 25768.325414765826 18431.331420792685 18654.227573898457 1.5666620682295238 1.3391745893562375 1.406988296703677 0.8810342040780506 1.024856865509884 0.7651839646794636 1.4406543549400377 1.3813665193417939 0.9880511721955373 1.0 14.187215002455275 -5.672611138809103 8.406188153130723 1.085984694040467 1.4315669509287268 0.41161817667226497 0.20143481575359565 0.30073029864277184 25.241366813238443 0.05885015142883629 0.10207346845528692 2.1251464367002596e-06 5.672611138809103 0.34558225688825983 EENISAPLISSS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 1 EENISAPLISSSPVK 15 0 A2A2Y4-4;A2A2Y4-3;A2A2Y4-5;A2A2Y4-2;A2A2Y4 A2A2Y4-4 FRMD3 FERM domain-containing protein 3 1 EENISAPLIS(0.014)S(0.067)S(0.919)PVK 86.214 0.0055474 2495600.0 34449.0 35041.0 18963.0 16720.0 15316.0 17148.0 15552.0 15782.0 22529.0 8205.0 True False 33957.75094282713 34959.86471741263 17403.935339296844 17949.644576284933 14415.142992414569 16414.620013940395 16357.20646347957 16515.289335023575 19991.546779112632 9623.223317524727 3.52872938955777 3.632864328706544 1.8085349123721115 1.865242443620431 1.4979537018706963 1.7057299277309654 1.699763782234137 1.716191008988412 2.077427294314815 1.0 13.232304493139068 -5.276050738377767 5.779343741191054 1.694298784326483 3.5942413590047413 0.8913820296798871 0.26662914210237304 0.040835584575071346 5.371534973117319 0.06538953644859911 0.15101122013952 5.296015672267824e-06 5.276050738377767 1.8999425746782583 EENMDTSNT(ph)SISK ddPTM_PC-9_AZD4547_30min_R2 1 EENMDTSNTSISK 13 0 H0YA82;Q4G0J3;Q4G0J3-3;D6RFF0 H0YA82 LARP7 La-related protein 7 1 EENMDT(0.003)S(0.003)NT(0.494)S(0.494)IS(0.006)K 97.273 0.009344700000000001 0.0 12315.0 14019.0 18917.0 20778.0 19749.0 19072.0 18818.0 21595.0 17536.0 21356.0 True False 16230.913832087217 18550.36759351318 18666.148219851766 15987.95311689993 17007.19224255401 17879.42482504146 20492.765544703565 18257.988953732798 18462.917159546465 20608.332940260498 0.7875898491710825 0.9001391644480436 0.9057573105967017 0.7758004086621592 0.8252580299364589 0.8675822967762795 0.9943922006747494 0.8859517655629456 0.895895714275717 1.0 14.330940185926277 -7.057094440611378 7.538418824206195 0.9344175425550934 0.8428478250406629 0.4763699764283157 0.05180026257545558 0.2972959175289337 34.99081795047542 0.020195891813415048 0.01572473762801085 8.768101314332521e-08 7.057094440611378 -0.09156971751443044 EENMDTSNT(ph)SISK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EENMDTSNTSISK 13 0 H0YA82;Q4G0J3;Q4G0J3-3;D6RFF0 H0YA82 LARP7 La-related protein 7 1 EENMDT(0.035)S(0.035)NT(0.562)S(0.307)IS(0.062)K 81.128 0.043746 0.0 17473.0 16648.0 19170.0 18381.0 22952.0 19055.0 19552.0 20354.0 16682.0 13765.0 True False 20430.833792519148 18300.703417200963 19627.085502629852 17351.172162006045 18454.720362310592 18055.722255589644 17699.893015778336 19819.729066845637 16925.942690756627 16260.48553631996 1.2564713241117038 1.1254709077612661 1.2070417859780473 1.0670758953199702 1.1349427617699064 1.1104048655410557 1.0885218019008884 1.218889129883338 1.0409248022114888 1.0 13.989082716321722 -2.468445936282021 0.01713676194131492 9.463081559869185e-07 2.4711573873999186 0.4460874004542066 0.05789998069450198 3675.5984078353217 5.722584594799232 331.7512863844573 510.73762283205974 0.0034005883583928887 2.468445936282021 2.471156441091763 EENMDTSNTS(ph)ISK ddPTM_PC-9_AZD4547_30min_R2 1 EENMDTSNTSISK 13 0 H0YA82;Q4G0J3;Q4G0J3-3;D6RFF0 H0YA82 LARP7 La-related protein 7 1 EENMDT(0.014)S(0.014)NT(0.092)S(0.85)IS(0.031)K 85.976 0.032526 0.0 16439.0 19337.0 21088.0 24657.0 23586.0 25994.0 21135.0 23433.0 23507.0 19346.0 True False 21666.260047558408 25587.30709435514 20808.359341345567 18972.70959685253 20311.491023995077 24368.59107079109 23015.97405607981 19811.968286771033 24749.532029508347 18668.702428464105 1.1605659327733424 1.3705991186265984 1.114611978046162 1.0162843223600213 1.0879969350749423 1.3053178797063254 1.2328641556248405 1.0612397065456352 1.3257232056885122 1.0 14.188334035818686 -11.78947707477862 2.329730705355896 0.23608954152212133 1.182780111034146 0.19312748827884352 0.11395164000824418 2018887.8803856901 1080228.8613591995 7892248.351085397 0.02953000540520695 1.6237640622970221e-12 11.78947707477862 0.9466905695120247 EENPES(ph)DGEPVVEDGTSVK ddPTM_PC-9_AZD4547_30min_R2 2 EENPESDGEPVVEDGTSVK 19 0 Q13439-3;Q13439-4;Q13439;H0Y6I0;Q13439-5;E7EVX2;A0A087WTW2 Q13439-3;Q13439-5 GOLGA4 Golgin subfamily A member 4 1 EENPES(1)DGEPVVEDGTSVK;EENPES(1)DGEPVVEDGTSVK 186.6 6.262e-11 38700000.0 66732.0 82417.0 91288.0 70786.0 72042.0 96547.0 95363.0 112745.0 106933.0 74928.0 True False 87951.38788817251 109056.68349772287 90077.46147348048 54467.38133279812 62040.21183543853 90509.90082756292 103850.12225739007 95322.85087235973 112585.26007195386 72304.79352630838 1.2163977462458426 1.508291195908639 1.2458020703800978 0.7533024945708469 0.8580373279520529 1.251782854405504 1.4362826749460782 1.3183475980423918 1.5570926155952478 1.0 16.141803674960833 -6.99516224361477 24.97601047861883 1.3529701553574742 1.1181354159299772 0.15109345630255422 0.23522828815608074 257.4602652027987 1329186.5222598524 0.09074237684806195 0.07975675922031175 1.0112016192618563e-07 6.99516224361477 -0.234834739427497 EENPES(ph)DGEPVVEDGTSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EENPESDGEPVVEDGTSVK 19 0 Q13439-3;Q13439-4;Q13439;H0Y6I0;Q13439-5;E7EVX2;A0A087WTW2 Q13439-3;Q13439-5 GOLGA4 Golgin subfamily A member 4 1 EENPES(1)DGEPVVEDGTSVK;EENPES(1)DGEPVVEDGTSVK 151.22 1.8169e-14 16175000.0 40756.2 69857.0 63877.0 43678.7 59060.0 41172.3 56650.0 35477.5 40557.8 39057.7 True False 47655.41968835742 76791.94129117044 65400.06993487154 41231.52404725602 47487.616965757414 39013.152108308204 51283.701889517295 34546.25321651844 41150.88109718076 46138.55182941692 1.0328763647491288 1.6643769309250316 1.4174712326617478 0.893645821388085 1.029239433897454 0.8455651632185447 1.1115152048794894 0.7487502716652782 0.8918979782747292 1.0 15.493685101790835 -5.7600554485423405 24.98957874104781 0.9290379554696749 1.40085515792928 0.5775004322127579 0.17193181639716154 23.008930290981912 415453.08818053536 0.0454566252208113 0.07355657155527791 1.7375789692143768e-06 5.7600554485423405 0.4718172024596051 EENPES(ph)DGEPVVEDGTSVK ddPTM_PC-9_Lapatinib_30min_R1 3 EENPESDGEPVVEDGTSVK 19 0 Q13439-3;Q13439-4;Q13439;H0Y6I0;Q13439-5;E7EVX2;A0A087WTW2 Q13439-3;Q13439-5 GOLGA4 Golgin subfamily A member 4 1 EENPES(1)DGEPVVEDGTSVK;EENPES(1)DGEPVVEDGTSVK;EENPES(1)DGEPVVEDGTSVK 178.1 3.2299e-09 36054000.0 90578.8 118358.2 95988.6 91931.8 119647.4 116996.8 116340.7 123032.0 111765.6 101685.9 True False 89287.12970188253 118084.14885980595 88096.78783471124 98692.7712474949 112609.97516783896 111993.11959686158 122364.25218658283 128748.5158703979 99177.38118405586 119262.1723270554 0.7486626141357577 0.9901224047469224 0.7386817304746168 0.8275278684078253 0.9442220695010152 0.9390498044068849 1.026010593292067 1.0795419315131027 0.8315912686218682 1.0 16.863776994836833 -6.425704750434801 2.532517459007212 0.9832388482178936 0.8313498124109252 0.3921891857326296 0.08785975146507671 0.3068960378961484 3.858225676912532 0.029491044234063065 0.03355587322010695 3.7522800953113596e-07 6.425704750434801 -0.15188903580696844 EENQEVMKK ddPTM_PC-9_AZD4547_30min_R2 1 EENQEVMKK 9 1 E5RI37;B4DU55 E5RI37 ZNF879 Zinc finger protein 879 0 31.871 0.041227999999999994 1737600.0 6087.6 4406.1 6886.5 12179.0 8891.3 7714.6 6416.6 8032.9 6795.8 8131.2 False True 8023.330170053936 5830.285659018362 6795.180510440836 9371.319713674286 7656.896470009645 7232.204842453059 6987.6649693987065 6791.599882678404 7155.012114099333 7846.529162944661 1.0225323838652407 0.7430400802627439 0.8660109928006343 1.194326755061393 0.9758322834214955 0.9217075081562487 0.8905421523694894 0.8655546601103359 0.9118696898354719 1.0 12.937838917427758 -10.294909415193015 14.920688557825223 1.0 0.9303312926421029 0.031425376182021125 0.11210462658235058 0.0 0.0 0.11435166199487469 0.027734351815870424 5.070964670334916e-11 10.294909415193015 -0.0696687073578971 EEPAPEEEEPLLLQRPER ddPTM_PC-9_Lapatinib_30min_R1 1 EEPAPEEEEPLLLQRPER 18 1 Q9BVJ6-3;Q9BVJ6;Q9BVJ6-2 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 0 102.29 0.0041394 0.0 3207.7 3332.4 4185.9 3449.8 4015.8 3382.5 3105.3 3362.6 4197.0 2911.9 False True 3161.957609779863 3324.6840325420476 3841.751460041269 3703.509800195439 3779.5985393665733 3237.838359992618 3266.077239650409 3518.8386717748235 3724.289663630689 3415.218035137144 0.9258435558867296 0.9734910036010451 1.1248920041168022 1.0844138681900344 1.1066931892724081 0.9480619763307724 0.9563305200569 1.0303408554217004 1.0904983592009914 1.0 11.737761970987068 -5.015875283118446 17.634922415239114 1.0415974318495176 0.9377525283514949 0.3072080247979855 0.05780847648096743 17.5134486741847 19466.833396662118 0.01609486754454914 0.04650657904736236 9.641058473384222e-06 5.015875283118446 -0.10384490349802267 EEPCLLK ddPTM_PC-9_Lapatinib_30min_R1 1 EEPCLLK 7 0 Q60FE5;P21333-2;P21333;H0Y5F3;H7C2E7 Q60FE5 FLNA Filamin-A 0 107.66 0.045498000000000004 6205200.0 32568.0 37033.0 33225.0 35262.0 33646.0 34639.0 36827.0 40365.0 27830.0 34588.0 False True 32103.574347760274 36947.25236380075 30493.3687522089 37855.285110583696 31667.008430581125 33157.57071745287 38733.72186410509 42240.50525967729 24695.492337107953 40566.48971438701 0.7913816199969271 0.9107825849348091 0.7516886219858049 0.9331663985991429 0.780619882408764 0.8173635666014616 0.9548206447443265 1.041265969944069 0.6087658190535927 1.0 15.308000848700745 -7.242658756329977 24.19766971637486 0.9046519450799586 0.8332393377833587 0.07517315510902656 0.12051636952840107 1508.3493180182702 1943417.0460279235 0.04403733892114045 0.03404179802955025 5.719278482338618e-08 7.242658756329977 -0.07141260729659993 EEPCLLKR ddPTM_PC-9_AZD4547_30min_R2 2 EEPCLLKR 8 1 Q60FE5;P21333-2;P21333;H0Y5F3;H7C2E7 Q60FE5 FLNA Filamin-A 0 ; 64.567 0.034269 5153100.0 26888.0 23766.0 36891.0 54623.0 47149.0 37289.0 28392.0 32445.0 28263.0 35334.0 False True 35437.82469485678 31447.894730539563 36401.80123584881 42030.511266937414 40603.17520098128 34957.31293524384 30918.832997407997 27431.370761929185 29756.92447994194 34096.967414832565 1.0393248250998688 0.9223076746954151 1.0675964461289194 1.2326759372932874 1.1908148518603574 1.0252323178757832 0.9067912879536013 0.8045105721043165 0.8727146938879187 1.0 15.057355811170249 -7.201182504123732 3.3237843345930904 0.8765229092820674 1.0887294587311838 0.49806899909315083 0.09129614577793861 0.2229846695551525 4.908925636076955 0.04291588914206594 0.03112646465075978 6.292417002473582e-08 7.201182504123732 0.21220654944911632 EEPCLLKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEPCLLKR 8 1 Q60FE5;P21333-2;P21333;H0Y5F3;H7C2E7 Q60FE5 FLNA Filamin-A 0 67.98100000000001 0.028375 1859600.0 11596.0 8708.8 13712.0 15081.0 18144.0 17234.0 16555.0 13460.0 15262.0 14329.0 False True 13558.973768560189 9573.35210954588 14038.946083049585 14236.060463261681 14588.813447793804 16330.21870127692 14986.790552179325 13106.68926204886 15485.177877132703 16926.734271698406 0.8010389689422175 0.5655758491791638 0.8293948411846213 0.8410399924021053 0.8618799830860688 0.9647589688095438 0.8853917307154353 0.7743188409333818 0.9148355275491036 1.0 14.047016035919812 -5.45335052077883 5.589682185341717 0.8807835367034734 0.6831826169753288 0.5123518972991086 0.07974665342298984 0.16608190815516335 9.659610656764515 0.020303142097992447 0.04260672096253295 3.5208658587040373e-06 5.45335052077883 -0.19760091972814464 EEPCLLKR ddPTM_PC-9_Lapatinib_30min_R1 2 EEPCLLKR 8 1 Q60FE5;P21333-2;P21333;H0Y5F3;H7C2E7 Q60FE5 FLNA Filamin-A 0 ; 72.789 0.020073 7191700.0 54726.0 40583.0 54637.0 47803.0 46516.0 44073.0 43248.0 34082.0 55096.0 43453.0 False True 53945.597204480706 40489.03255691209 50144.956764919116 51318.592086133285 43780.02033397466 42188.10052918096 45487.16982591077 35665.57414245811 48890.508293399194 50963.79315251702 1.0585082833815014 0.7944666213470887 0.9839329779644265 1.0069617842721101 0.859041637716333 0.8278053480620361 0.8925389381787849 0.6998218134141501 0.9593184743350401 1.0 15.637185038593252 -6.292629088762865 20.30859067221779 0.8567870321961635 0.9507147987267633 0.14414913239889993 0.09903739340932251 119.68253753499975 77927.75522801602 0.02941624290820437 0.03336733003775781 5.097660532823234e-07 6.292629088762865 0.09392776653059987 EEPDSENIPQELLS(ph)NLGHPESPPR ddPTM_PC-9_AZD4547_30min_R2 1 EEPDSENIPQELLSNLGHPESPPR 24 0 D6R9R7;A0A0A0MTL5;Q13309-2;Q13309;D6RF40;D6RAG5 D6R9R7 SKP2 S-phase kinase-associated protein 2 1 EEPDS(0.001)ENIPQELLS(0.673)NLGHPES(0.326)PPR 49.25 0.018787 1043500.0 910.03 1282.0 2672.6 2418.1 2255.9 3547.5 2587.5 5300.8 3643.9 2790.0 True False 1199.4006102001088 1696.381429123612 2637.159577754182 1860.6444042725827 1942.707224668469 3325.674264200638 2817.7824873483073 4481.683160266118 3836.5091148307106 2692.3229492099085 0.44548913069737267 0.6300809602434335 0.9795108638538647 0.6910925766979809 0.7215728801177353 1.2352434410502622 1.0465989929533588 1.664615740686427 1.4249810246414072 1.0 11.394635758978316 -6.903584493723778 1.4128721929509809 1.371526379224482 0.6816199866400061 0.6301668126150438 0.21884014673987462 0.2606496156843247 1.0739363519602798 0.1087150982711292 0.08689218262042728 1.2485775052247553e-07 6.903584493723778 -0.689906392584476 EEPDSENIPQELLSNLGHPES(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 4 EEPDSENIPQELLSNLGHPESPPR 24 0 D6R9R7;A0A0A0MTL5;Q13309-2;Q13309;D6RF40;D6RAG5 D6R9R7 SKP2 S-phase kinase-associated protein 2 1 EEPDSENIPQELLSNLGHPES(1)PPR;EEPDSENIPQELLS(0.005)NLGHPES(0.995)PPR;EEPDSENIPQELLS(0.001)NLGHPES(0.999)PPR;EEPDSENIPQELLSNLGHPES(1)PPR 134.98 7.9013e-09 69661000.0 61867.4 71111.0 100894.0 88041.0 91194.0 118149.0 101496.0 151984.0 105594.0 95565.0 True False 81539.9462781384 94096.2400986031 99556.07963703146 67744.50766989056 78533.28722302266 110761.12435265431 110528.94737619486 128498.36504487696 111175.48326557635 92219.29843772232 0.8841961244500693 1.0203530247212662 1.0795579810690474 0.7346022884314164 0.8515927636996489 1.2010623180727589 1.1985446565811542 1.393399941462954 1.20555550897685 1.0 16.492781069976488 -6.794047058208579 8.732366608531093 1.2249411271359814 0.919235926146964 0.5620117017150521 0.1250651804172139 0.19680934446019743 47.76947617396571 0.045270021088586916 0.040315978384926184 1.6067671414755512e-07 6.794047058208579 -0.3057052009890173 EEPDSENIPQELLSNLGHPES(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 EEPDSENIPQELLSNLGHPESPPR 24 0 D6R9R7;A0A0A0MTL5;Q13309-2;Q13309;D6RF40;D6RAG5 D6R9R7 SKP2 S-phase kinase-associated protein 2 1 EEPDSENIPQELLS(0.001)NLGHPES(0.999)PPR;EEPDSENIPQELLSNLGHPES(1)PPR;EEPDSENIPQELLSNLGHPES(1)PPR;EEPDSENIPQELLS(0.004)NLGHPES(0.996)PPR;EEPDSENIPQELLSNLGHPES(1)PPR;EEPDSENIPQELLSNLGHPES(1)PPR;EEPDSENIPQELLSNLGHPES(1)PPR;EEPDSENIPQELLS(0.003)NLGHPES(0.997)PPR 161.95 2.189e-09 79485100.0 79894.19 137488.2 155949.8 113755.40000000001 138815.9 115032.1 122872.9 76981.91 100865.65000000001 94852.62000000001 True False 93418.69838481929 151137.1198681408 159668.23467490988 107382.05373798263 111615.92089327624 108999.61417356138 111233.48938924042 74961.21643157578 102340.61931218754 112048.64915307343 0.8337333746629721 1.348852672571423 1.4249902687963845 0.9583520600171126 0.9961380323362397 0.9727882932765511 0.9927249478686763 0.6690059808679062 0.9133587962526578 1.0 16.773765730407746 -5.899586682373692 8.190995918022157 0.9191199334192686 1.216397672908145 0.3510750166447498 0.1705726464631231 0.2613090884698748 19.03049566510625 0.04919546168487485 0.07320282868068398 1.2601241001607404e-06 5.899586682373692 0.29727773948887637 EEPDSENIPQELLSNLGHPES(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 6 EEPDSENIPQELLSNLGHPESPPR 24 0 D6R9R7;A0A0A0MTL5;Q13309-2;Q13309;D6RF40;D6RAG5 D6R9R7 SKP2 S-phase kinase-associated protein 2 1 EEPDSENIPQELLS(0.001)NLGHPES(0.999)PPR;EEPDSENIPQELLSNLGHPES(1)PPR;EEPDSENIPQELLSNLGHPES(1)PPR;EEPDSENIPQELLS(0.004)NLGHPES(0.996)PPR;EEPDSENIPQELLSNLGHPES(1)PPR;EEPDSENIPQELLS(0.004)NLGHPES(0.996)PPR 146.34 2.4003e-09 72306000.0 123807.8 107698.5 119366.0 88173.1 123585.4 115448.9 104707.1 109171.0 124922.1 87901.7 True False 122042.27806843008 107449.13074022596 109552.1882460846 94657.64391083915 116316.34975024496 110511.41967153056 110128.32130222491 114243.48320832977 110852.0576099687 103095.39172334701 1.1837801479616703 1.0422302000516381 1.0626293417659654 0.9181559168507718 1.1282400484240453 1.0719336511964008 1.0682176910268746 1.1081337516510754 1.075237755606346 1.0 16.65362032133818 EEPEALY(ph)AAVNK ddPTM_PC-9_AZD4547_30min_R2 2 EEPEALYAAVNK 12 0 A0A087WVF7;Q9NZM3-4;Q9NZM3-3;Q9NZM3-2;Q9NZM3 A0A087WVF7 ITSN2 Intersectin-2 1 EEPEALY(1)AAVNK;EEPEALY(1)AAVNK 127.42 0.00034014 1665200.0 24061.2 29716.8 30633.7 34800.3 30117.8 33263.4 29687.9 37654.7 31550.6 31070.4 True False 31712.161095949417 39322.17445630307 30227.477122295993 26777.628494275323 25936.463341070084 31183.434339622676 32330.06558691703 31836.031333925548 33218.3003041735 29982.63475309373 1.0576842681471557 1.311498298268989 1.0081661392075292 0.8931045825288019 0.8650495046434789 1.040049835393637 1.0782930137112476 1.0618156675053574 1.1079179857849517 1.0 14.871839546631177 -5.333556946042705 11.236931325359834 1.0035252974173292 1.184485879970763 0.37312565080093973 0.09210345966654969 0.7823694725461734 120.14554298462019 0.025669507253985743 0.0534728712465277 4.639199553669082e-06 5.333556946042705 0.18096058255343372 EEPEALY(ph)AAVNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEPEALYAAVNK 12 0 A0A087WVF7;Q9NZM3-4;Q9NZM3-3;Q9NZM3-2;Q9NZM3 A0A087WVF7 ITSN2 Intersectin-2 1 EEPEALY(1)AAVNK 143.96 2.3706e-05 0.0 14550.0 11923.0 11075.0 11093.0 13157.0 8758.3 12013.0 9473.6 8787.2 11241.0 True False 17013.02762440071 13106.636643638092 11339.070002171393 10471.495173991245 10578.980298314766 8298.999329894024 10875.041673411679 9224.928038108912 8915.696176250849 13278.90431629296 1.2812071854095715 0.9870269663406266 0.8539160861531755 0.7885812657858317 0.7966756929888079 0.6249762128123261 0.8189713107630584 0.6947055132244686 0.6714180600963787 1.0 13.696848489889067 -4.278640060461041 0.9009038530865595 0.7481501235480258 2.164157023932591 0.7212725587103859 0.09755200597965817 2.2712820494650123 0.7711379298454498 0.031133301823527863 3.9235500222617765 5.264534056954633e-05 4.278640060461041 1.416006900384565 EEPEALY(ph)AAVNK ddPTM_PC-9_Lapatinib_30min_R1 1 EEPEALYAAVNK 12 0 A0A087WVF7;Q9NZM3-4;Q9NZM3-3;Q9NZM3-2;Q9NZM3 A0A087WVF7 ITSN2 Intersectin-2 1 EEPEALY(1)AAVNK 125.68 0.0004144 3082000.0 8842.8 12550.0 13933.0 14362.0 11598.0 10471.0 14262.0 11939.0 12985.0 11204.0 True False 8716.700050429086 12520.941246069706 12787.482522935332 15418.229390227518 10915.828442545315 10023.17973909318 15000.416575498055 12493.729525462337 11522.49256188813 13140.596471608407 0.6633412774878524 0.9528442086417059 0.9731280121540895 1.1733279705788218 0.8306950499644419 0.7627644422952397 1.1415323960299655 0.9507733954433734 0.876862217539641 1.0 13.681743142812499 -4.761445545281402 6.035675108133928 0.9637638609815179 0.6524318052566263 0.3609150779105812 0.11947735692213403 0.1538650209336089 21.9073932939944 0.030477436150616044 0.1982655741899822 1.7320261900508076e-05 4.761445545281402 -0.31133205572489164 EEPGS(ph)PLSPAPR ddPTM_PC-9_AZD4547_30min_R2 3 EEPGSPLSPAPR 12 0 B2RBV5 B2RBV5 LOC93622 1 EEPGS(0.999)PLS(0.001)PAPR;EEPGS(0.982)PLS(0.018)PAPR;EEPGS(1)PLSPAPR 130.15 0.00057701 18129100.0 214763.0 196884.0 236943.0 328039.0 331876.0 278560.0 244097.0 335791.0 236511.0 308726.0 True False 283053.16665209475 260522.9027235362 233800.98100419386 252414.67670202817 285800.74599675235 261141.59916440625 265821.1601214534 283902.2166595452 249012.48861322406 297917.59670888097 0.9501055653610436 0.8744797407120395 0.7847840597098379 0.8472634026672908 0.9593281805237944 0.8765564775268663 0.8922640456891455 0.9529555145309818 0.8358435062718166 1.0 18.184553814321276 -6.23579902981292 24.563416313036164 0.9136309669931747 0.8592258584802376 0.1752552607119604 0.05757838458006534 1140.1187250987787 1092231.3621307504 0.016912914725155704 0.02182661908325613 5.810332290028454e-07 6.23579902981292 -0.05440510851293712 EEPGS(ph)PLSPAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EEPGSPLSPAPR 12 0 B2RBV5 B2RBV5 LOC93622 1 EEPGS(1)PLSPAPR;EEPGS(0.999)PLS(0.001)PAPR;EEPGS(1)PLSPAPR;EEPGS(1)PLSPAPR 156.52 9.510600000000001e-05 57246600.0 299097.0 333204.0 354414.0 397435.0 440265.0 346397.0 351334.0 328593.0 347993.0 307498.0 True False 349728.2146649738 366282.29105147877 362864.5738825807 375168.0054516556 353998.23371874646 328231.33152293274 318053.1000821123 319967.7819230623 353081.7392869249 363244.9532471721 0.9627889156852214 1.0083616792942471 0.9989528295955908 1.0328237243157798 0.9745441211343309 0.9036087868221141 0.8755884899127319 0.8808595386192148 0.9720210456624524 1.0 18.470583228314595 -6.622348707324864 4.410486235908642 0.9161048518509433 1.0014638513181708 0.42874441819258435 0.039766655329227955 0.17933503168336196 6.196183367176435 0.013268946065149034 0.013257967490050452 2.385894811185245e-07 6.622348707324864 0.08535899946722758 EEPGS(ph)PLSPAPR ddPTM_PC-9_Lapatinib_30min_R1 2 EEPGSPLSPAPR 12 0 B2RBV5 B2RBV5 LOC93622 1 EEPGS(1)PLSPAPR;EEPGS(1)PLSPAPR 151.7 0.00010909 16138400.0 80841.0 76932.0 77189.0 65857.0 71249.0 71185.0 59695.0 58496.0 63325.0 54907.0 True False 79688.19251557629 76753.86868068817 70842.8183781567 70700.34347251171 67058.27390092357 68140.5834903399 62785.71501012175 61213.93771014697 56192.67165818761 64397.60179102132 1.2374403750961867 1.1918746435583822 1.1000847299880974 1.0978723043436247 1.0413163229049505 1.0581229982983689 0.974969770052457 0.9505623813258488 0.8725895079220529 1.0 15.974719341979032 -5.644053325356573 0.446733614578158 0.9302391410124875 1.3183782151876657 0.8638393135107546 0.03863658597760137 0.8583435625760811 0.23183440967171273 0.032665195790405915 0.1643068442690764 2.2695861609797347e-06 5.644053325356573 0.38813907417517823 EEPGSPLS(ph)PAPR ddPTM_PC-9_AZD4547_30min_R2 3 EEPGSPLSPAPR 12 0 B2RBV5 B2RBV5 LOC93622 1 EEPGS(0.006)PLS(0.994)PAPR;EEPGSPLS(1)PAPR;EEPGS(0.003)PLS(0.997)PAPR 130.69 0.00013868 33482500.0 53959.1 54835.0 72069.0 95281.0 78827.0 66365.0 58035.0 71632.0 56356.0 72872.0 True False 71116.97138099687 72559.34139313045 71113.31797095193 73315.43752677557 67883.23170306378 62215.1860588232 63200.002571307814 60562.92033960586 59334.86310694571 70320.77346051048 1.0113223714886115 1.0318336648256161 1.0112704179922953 1.0425857668921514 0.9653368181620537 0.8847340977237819 0.8987387291295733 0.8612379722133707 0.8437743242438304 1.0 16.101663318368452 -6.5743646830131075 3.002216928345823 0.8886974411764736 1.0234654372522418 0.6840658536943492 0.04026241471487429 0.13544359444288764 2.4907815814796344 0.013376592598984553 0.013795425702085347 2.6646202068091596e-07 6.5743646830131075 0.13476799607576817 EEPGSPLS(ph)PAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EEPGSPLSPAPR 12 0 B2RBV5 B2RBV5 LOC93622 1 EEPGS(0.001)PLS(0.999)PAPR;EEPGS(0.009)PLS(0.991)PAPR 113.07 0.00087806 7859500.0 21934.1 23370.6 30841.0 24166.0 40805.0 31844.0 29946.0 36767.0 31852.0 22565.7 True False 25647.109911777832 25690.67871708534 31576.366405143814 22812.057367229096 32809.553171143416 30174.044581841837 27109.29808973496 35801.90520785663 32317.775241936244 26656.682780017087 0.9621268378901192 0.9637612800173357 1.1845572333859455 0.8557725488758086 1.230819057341177 1.1319504692632463 1.016979431141266 1.3430742865985998 1.2123704779261935 1.0 14.702209638799266 -6.2807913020416155 24.982278891289397 1.1648792686180764 1.0033551403791041 0.30338265456009916 0.1209888698677274 1043.023170913853 1346482.71468341 0.03721750918550406 0.04226322274935927 5.238521105224319e-07 6.2807913020416155 -0.16152412823897233 EEPGSPLS(ph)PAPR ddPTM_PC-9_Lapatinib_30min_R1 1 EEPGSPLSPAPR 12 0 B2RBV5 B2RBV5 LOC93622 1 EEPGS(0.007)PLS(0.993)PAPR 115.92 0.00070057 3940900.0 13168.0 9142.2 14630.0 8517.7 12708.0 15196.0 12761.0 13985.0 18088.0 10401.0 True False 12980.22190528455 9121.031797595097 13427.177873433138 9144.12007221424 11960.540424889286 14546.102503606158 13421.702139947452 14634.794154752544 16050.738964915872 12198.798991538655 1.0640573645231721 0.7476991631652949 1.1006967065156588 0.7495918310119541 0.9804686865637651 1.1924208697672323 1.1002478317133537 1.1996913929726645 1.3157638695456007 1.0 13.574451496661982 -6.663065261658648 4.449019874456651 1.1702356939255565 0.911422365360988 0.44877859079992044 0.13015768099458228 0.18396452699174104 6.419043221276476 0.04160752146794141 0.04116917885076641 2.172374710452596e-07 6.663065261658648 -0.2588133285645685 EEPLS(ph)EEEPCTSTAIAS(ph)PEKK ddPTM_PC-9_AZD4547_30min_R2 2 EEPLSEEEPCTSTAIASPEKK 21 1 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 2 EEPLS(0.989)EEEPCT(0.025)S(0.015)T(0.062)AIAS(0.91)PEKK;EEPLS(0.968)EEEPCT(0.021)S(0.023)T(0.018)AIAS(0.97)PEKK 64.383 0.0035021 33052400.0 33234.0 39314.0 28264.0 27004.0 26672.0 31475.0 35072.0 32865.0 32961.0 33260.0 True False 43801.720689856804 52021.4816728281 27889.200892630466 20778.64500764104 22969.053192232564 29506.863274338295 38193.34005653329 27786.46941256904 34703.25116878482 32095.577523556087 1.3647276064033795 1.6208302104751873 0.8689421734867238 0.6473990066821778 0.7156454242138114 0.9193435841022695 1.1899876245723213 0.8657413748724591 1.0812471326716233 1.0 14.970086900436396 -5.26720719890833 24.840445897231618 0.9001084100858417 1.4927789261644182 0.6751899801784718 0.16125287716623485 228.97049589408516 986118.5464456825 0.04545219818228204 0.098924072150364 5.4049639431266874e-06 5.26720719890833 0.5926705160785765 EEPLS(ph)EEEPCTSTAIAS(ph)PEKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EEPLSEEEPCTSTAIASPEKK 21 1 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 2 EEPLS(0.997)EEEPCT(0.002)S(0.001)T(0.002)AIAS(0.998)PEKK;EEPLS(0.999)EEEPCT(0.016)S(0.033)T(0.08)AIAS(0.873)PEKK;EEPLS(0.999)EEEPCT(0.004)S(0.003)T(0.009)AIAS(0.985)PEKK 74.65 0.0011585999999999999 23465100.0 124917.0 171371.0 112174.0 119223.0 118974.0 98257.0 140350.0 111226.0 97131.0 104015.0 True False 146062.9808767881 188383.5803285163 114848.65358226406 112543.32183618119 95661.89876200506 93104.2299484372 127055.03195399384 108306.43535368842 98551.35712120119 122872.09611771312 1.1887400434420667 1.5331681177477618 0.9347008573227032 0.9159388127338787 0.7785486028525116 0.7577329018562693 1.0340430086931487 0.8814567243154166 0.8020645877709098 1.0 16.90679779565309 -5.3520788660665986 5.900896497918255 0.8780169656288644 1.3582315497650401 0.731353403163437 0.11477187836390793 0.09871430477335866 5.117258477929885 0.029379542374439144 0.06251580599265241 4.445505316162321e-06 5.3520788660665986 0.4802145841361757 EEPLS(ph)EEEPCTSTAIAS(ph)PEKK ddPTM_PC-9_Lapatinib_30min_R1 5 EEPLSEEEPCTSTAIASPEKK 21 1 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 2 EEPLS(0.959)EEEPCT(0.025)S(0.012)T(0.004)AIAS(1)PEKK;EEPLS(1)EEEPCTST(0.001)AIAS(0.999)PEKK;EEPLS(1)EEEPCTSTAIAS(1)PEKK;EEPLS(0.993)EEEPCT(0.008)S(0.008)T(0.015)AIAS(0.977)PEKK;EEPLS(0.908)EEEPCT(0.026)S(0.034)T(0.041)AIAS(0.991)PEKK 107.31 4.965e-05 94217100.0 216984.0 338181.0 221473.0 255982.0 276611.0 245366.0 293197.0 293716.0 240712.0 237518.0 True False 213889.76837000748 337397.9626722795 203264.3448505034 274807.7702109195 260341.28481815013 234872.26815608243 308377.306036061 307363.11762297386 213600.47975026668 278572.66982715944 0.7678060037358134 1.2111667769907875 0.7296636277227729 0.9864850359564136 0.9345542941440703 0.8431274622230854 1.1069905250482537 1.1033498649155982 0.7667675363947052 1.0 18.087694199572987 -7.250057844630596 24.74147799144565 1.002889477397935 0.9218308865246805 0.06209538160652717 0.15218235755412923 2001.9366622984342 4351868.273605444 0.056014015749189364 0.04299001900975612 5.6226643070881695e-08 7.250057844630596 -0.08105859087325462 EEPLS(ph)EEEPCTSTAIASPEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEPLSEEEPCTSTAIASPEK 20 0 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 1 EEPLS(1)EEEPCTSTAIASPEK 119.25 7.6178999999999995e-06 4218800.0 67096.0 113290.0 95749.0 71751.0 93071.0 61875.0 86648.0 42401.0 52145.0 61965.0 True False 78454.02759359402 124536.68249247341 98032.01929010478 67731.02408988052 74834.4056657638 58630.16607528778 78440.07416280474 41288.01867757305 52907.52197635203 73198.7639853299 1.0717944309731424 1.7013495271236052 1.3392578501701453 0.9253028384940325 1.0223452090087437 0.8009720777121061 1.0716038071151757 0.5640534953001087 0.7227925595431566 1.0 16.159531667303437 -5.765547094698216 3.518896089400857 0.858342466801399 1.4187029056060811 0.56614595504092 0.2003323996506605 0.15506725157504211 4.05673893263068 0.056971438705114515 0.0967770269582554 1.7157456453469682e-06 5.765547094698216 0.5603604388046821 EEPLS(ph)EEEPCTSTAIASPEK ddPTM_PC-9_Lapatinib_30min_R1 1 EEPLSEEEPCTSTAIASPEK 20 0 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 1 EEPLS(0.998)EEEPCT(0.001)S(0.001)T(0.001)AIASPEK 64.589 0.0038639000000000004 5337900.0 15952.0 22983.0 26597.0 16632.0 23970.0 27243.0 25486.0 27127.0 28002.0 22880.0 True False 15724.521554761475 22929.784275571306 24410.297327389027 17855.17276272554 22560.131726833173 26077.880396534776 26805.54037604426 28387.4194519823 24848.11988586765 26834.777514316378 0.5859754770231439 0.8544801336004462 0.9096515636981194 0.6653743543504241 0.8407050036020356 0.971794172044922 0.9989104758458862 1.0578593184473986 0.9259670542306958 1.0 14.711816306403746 -6.694387363139089 3.170240550887071 0.9983071403534557 0.7702229997431033 0.6075239419379477 0.08998003371604064 0.18070950940382266 3.6712863549669046 0.03220529884770825 0.03116079216666948 2.021215578319408e-07 6.694387363139089 -0.22808414061035243 EEPLS(ph)EEEPCTSTAIASPEKK ddPTM_PC-9_AZD4547_30min_R2 3 EEPLSEEEPCTSTAIASPEKK 21 1 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 1 EEPLS(1)EEEPCTSTAIASPEKK;EEPLS(0.991)EEEPCT(0.009)STAIASPEKK;EEPLS(1)EEEPCTSTAIASPEKK 132.36 1.9005e-06 100060000.0 142660.0 196069.0 189907.0 181160.0 169570.0 214463.0 179242.0 238435.0 194771.0 179329.0 True False 188022.9124876623 259444.46991172945 187388.70909697033 139396.36089409905 146028.13249125952 201052.59470705065 195194.19076223546 201590.34944122596 205066.19742712262 173050.74629349963 1.0865189345602093 1.4992392432200397 1.0828540940190634 0.8055230265096825 0.8438457251353954 1.1618129306767564 1.1279592543980124 1.164920428018971 1.1850061431074315 1.0 17.400835637677297 -5.493636312689552 23.762030695138954 1.040543016393075 1.2924211793786176 0.29177599382452724 0.15473355435863295 473.9245144757442 385103.14007449197 0.04306073378054909 0.08933455699099571 3.2089554462542675e-06 5.493636312689552 0.25187816298554266 EEPLS(ph)EEEPCTSTAIASPEKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EEPLSEEEPCTSTAIASPEKK 21 1 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 1 EEPLS(1)EEEPCTSTAIASPEKK;EEPLS(1)EEEPCTSTAIASPEKK;EEPLS(1)EEEPCTSTAIASPEKK;EEPLS(1)EEEPCTSTAIASPEKK 138.44 2.8872e-06 80678000.0 195366.0 236815.0 195214.0 219943.0 251099.0 178538.0 222901.0 121350.0 161018.0 172279.0 True False 228437.6051456126 260324.4281441885 199868.64211321788 207620.30677482692 201897.95347925375 169175.15298181365 201786.20361651003 118164.69108095308 163372.58363387207 203511.81894018615 1.122478322562447 1.2791612275879667 0.9820984508617702 1.0201879569257268 0.9920699177603698 0.8312792537692155 0.9915208102769536 0.5806281507202424 0.8027670554204455 1.0 17.63475305581415 -6.0340196519537175 0.6945390610916619 0.8012496606478983 1.2205496906620317 0.5095156093243074 0.12551828596368172 0.6916965218693547 0.6585891932382215 0.07195040427050353 0.17899573713750033 9.246563320191256e-07 6.0340196519537175 0.4193000300141334 EEPLS(ph)EEEPCTSTAIASPEKK ddPTM_PC-9_Lapatinib_30min_R1 4 EEPLSEEEPCTSTAIASPEKK 21 1 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 1 EEPLS(0.736)EEEPCT(0.251)S(0.006)T(0.007)AIASPEKK;EEPLS(0.999)EEEPCT(0.001)STAIASPEKK;EEPLS(1)EEEPCTSTAIASPEKK;EEPLS(1)EEEPCTSTAIASPEKK 157.3 5.181799999999999e-06 138748100.0 203599.0 239639.8 207210.8 165602.9 213637.8 237567.6 225907.7 225822.2 213343.7 153956.4 True False 200695.64092451587 239084.92876652587 190174.72788081903 177781.88970107972 201072.0446320753 227407.38754512387 237604.09533113442 236314.72381647155 189314.6858972423 180567.55860599235 1.111471199333453 1.3240746599903996 1.0532054005104539 0.9845727054936203 1.113555758212497 1.2594033463194705 1.315873666152837 1.3087330063099671 1.0484424076992513 1.0 17.46217919094107 -6.745050073600131 24.3062253151341 1.2138727411528345 1.117916181354797 0.04896205183926705 0.12614051103454593 407.1700426927656 603853.0120142135 0.04285726306309442 0.04272635031046697 1.7986635195618993e-07 6.745050073600131 -0.09595655979803741 EEPS(ph)PVKAEVAEK ddPTM_PC-9_AZD4547_30min_R2 1 EEPSPVKAEVAEK 13 1 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 EEPS(1)PVKAEVAEK 69.846 0.013953 120150000.0 139580.0 146080.0 153970.0 106770.0 118130.0 153100.0 156610.0 168630.0 134410.0 125900.0 True False 183963.53655564232 193297.5032499043 151928.2571977891 82155.82608005607 101729.68857222683 143526.63279749642 170547.98660622956 142572.1082319039 141514.6381965465 121492.27932097774 1.5141994008493167 1.5910270539843936 1.2505177946032333 0.6762226088705082 0.837334595587437 1.1813642282428893 1.4037763350842123 1.1735075597292408 1.16480354955454 1.0 16.89050510975551 -5.424162283192296 4.50131377683883 1.0722133479311318 1.5437761658234854 0.5059439150493303 0.1911504944920435 0.2049683979486242 6.8867004280304025 0.05818076118099226 0.12567446351017808 3.765630620478775e-06 5.424162283192296 0.47156281789235366 EEPS(ph)PVKAEVAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 EEPSPVKAEVAEK 13 1 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 EEPS(1)PVKAEVAEK;EEPS(1)PVKAEVAEK;EEPS(1)PVKAEVAEK;EEPS(1)PVKAEVAEK;EEPS(1)PVKAEVAEK 143.28 0.00041139 247453900.0 284810.0 505298.0 343486.0 301624.0 350990.0 241564.0 356797.0 223826.0 238283.0 259725.0 True False 333022.7077460877 555460.6460418544 351676.0089179096 284724.9851582022 282216.02910279727 228895.95859088167 322998.60517341737 217950.8046632505 241767.43808785334 306811.08651803125 1.08543244484914 1.81043212077413 1.146229795373583 0.9280140049354733 0.9198364775720432 0.7460485251318631 1.0527605401717932 0.7103746058747508 0.7880009840310797 1.0 18.226991089531907 -5.573392570508393 3.49517143181705 0.8697862814180365 1.4578357661210222 0.5787448218593221 0.19359403735501188 0.1395815723712398 3.494647669255027 0.05038517031204301 0.09828074213827627 2.6705912977042617e-06 5.573392570508393 0.5880494847029857 EEPS(ph)PVKAEVAEK ddPTM_PC-9_Lapatinib_30min_R1 3 EEPSPVKAEVAEK 13 1 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 EEPS(1)PVKAEVAEK;EEPS(1)PVKAEVAEK;EEPS(1)PVKAEVAEK 71.268 0.012405 268677000.0 399182.0 477955.0 350104.0 373087.0 440891.0 352471.0 425900.0 412863.0 343297.0 399251.0 True False 393489.59147898696 476848.32456296793 321319.80056052236 400525.0625617476 414958.65820505645 337396.6369800319 447951.0180552947 432046.1222104838 304631.2767823265 468261.00338148256 0.8403210787092154 1.0183387493715539 0.686198078080719 0.8553457573221149 0.88616958322066 0.7205311451168652 0.9566267846787965 0.9226609072515586 0.6505587152944055 1.0 18.836953370319726 EEPS(ph)QNDISPK ddPTM_PC-9_AZD4547_30min_R2 1 EEPSQNDISPK 11 0 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 EEPS(0.682)QNDIS(0.318)PK 124.21 0.00052314 178740000.0 99896.0 82755.0 77332.0 107330.0 91866.0 87273.0 108980.0 93603.0 76277.0 99818.0 True False 131660.85003412006 109503.93538777251 76306.52715216886 82586.72673196993 79111.99162258663 81815.80551362432 118679.00887776536 79138.80713295905 80308.84649741826 96323.40220223459 1.3668625383236896 1.1368362504250513 0.7921909464115526 0.857390051055049 0.8213164175460502 0.8493865835619985 1.2320890475670112 0.8215948079450532 0.8337417975416486 1.0 16.55559872942954 -4.987220164524286 3.3223487113370385 0.9009393478305526 1.3567480087826573 0.5867124914452092 0.12473316404138135 0.1774705075854891 3.904092845305481 0.03346530792172209 0.16084727299632884 1.029863901100719e-05 4.987220164524286 0.4558086609521047 EEPS(ph)QNDISPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEPSQNDISPK 11 0 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 EEPS(0.677)QNDIS(0.323)PK 134.56 6.2859e-05 5922400.0 28797.0 37096.0 21879.0 23439.0 31227.0 22526.0 32869.0 30373.0 18313.0 20325.0 True False 33671.76333332422 40778.6457210768 22400.678336569574 22125.78882026328 25108.293514895136 21344.69690524334 29755.410369047564 29575.740932853616 18580.792980207767 24009.761607388522 1.4024197276062254 1.6984194340575205 0.9329821221413633 0.9215330490184672 1.0457535533034432 0.8890007845256964 1.2393046984644336 1.2318215156185588 0.773884942468146 1.0 14.55133345868855 -5.265721760449838 24.99944895844399 1.0153662612929506 1.5504195974614101 0.6725765761534834 0.15226361070060557 191.72285895038092 1119235.2310306362 0.03988462989611235 0.08794541735056634 5.42348245500576e-06 5.265721760449838 0.5350533361684595 EEPS(ph)QNDISPK ddPTM_PC-9_Lapatinib_30min_R1 2 EEPSQNDISPK 11 0 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 EEPS(0.943)QNDIS(0.057)PK;EEPS(0.764)QNDIS(0.236)PK 130.69 0.00019665 411210000.0 86117.0 142438.0 155063.0 165630.0 164701.0 141815.0 163710.0 136351.0 131609.0 136599.0 True False 84888.95578807646 142108.1935623645 142314.31870048947 177810.98272548267 155013.6109946247 135749.90303691156 172186.1027608178 142686.36523379802 116785.80851579017 160209.95514327355 0.529860680081718 0.8870122548581897 0.888298848677785 1.1098622589742864 0.9675654103766409 0.8473250174467143 1.074752830476946 0.8906210922173692 0.7289547544742162 1.0 17.28960427130704 -4.683612278165353 2.497602864276869 0.9425631715101409 0.36381787918828223 0.5736914853276519 0.1048749419376714 0.5859776293607415 3.578020281516243 0.027680732805364153 0.8089215344282968 2.071990318614155e-05 4.683612278165353 -0.5787452923218587 EEPSQNDIS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 EEPSQNDISPK 11 0 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 EEPS(0.122)QNDIS(0.878)PK;EEPS(0.005)QNDIS(0.995)PK;EEPS(0.01)QNDIS(0.99)PK 153.0 0.00040395 169166900.0 147755.0 137657.0 122965.0 172220.0 162004.0 123842.0 153505.0 139889.0 133385.0 160168.0 True False 194738.0165050792 182151.9332206468 121334.40375609628 132517.33977247594 139512.54099259307 116098.14016268762 167166.64762141122 118272.36937942675 140435.45878912535 154560.5670713449 1.2599463122776229 1.1785149127756873 0.7850281999812314 0.8573812990172723 0.9026399400320154 0.7511498072409174 1.0815607809218724 0.7652169736465344 0.9086111771594405 1.0 17.237812766874768 -5.165435491176893 5.026098832540802 0.8758906514127058 1.2372859458882643 0.6531744497595933 0.09881214654907837 0.11977714998876363 4.779785480895989 0.023843187002023595 0.06738175015828483 6.83226194849076e-06 5.165435491176893 0.3613952944755585 EEPSQNDIS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 EEPSQNDISPK 11 0 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 EEPSQNDIS(1)PK;EEPS(0.107)QNDIS(0.893)PK;EEPS(0.019)QNDIS(0.981)PK;EEPS(0.083)QNDIS(0.917)PK;EEPS(0.006)QNDIS(0.994)PK 172.58 6.7623e-05 227675600.0 215854.0 257698.0 176123.0 232959.0 242212.0 166701.0 241607.0 265854.0 176460.0 133400.0 True False 252393.8188891682 283280.5543732486 180322.44027019688 219907.06249326823 194752.29733339074 157958.9060996613 218720.23587679793 258875.6141955966 179040.39367047802 157584.3640061807 1.6016425264074357 1.797643796450122 1.1442914492653875 1.3954878320582818 1.2358605408703636 1.002376771933197 1.387956459107957 1.6427747500725587 1.1361558286547755 1.0 17.265764867798104 -5.259381319190665 24.98616012490545 1.267827398685187 1.6996431857339924 0.4728367683920942 0.19139957218171744 157.4758554932377 1911824.3816480006 0.04995008840665172 0.11933613963356098 5.503242885475563e-06 5.259381319190665 0.4318157870488055 EEPSQNDIS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 EEPSQNDISPK 11 0 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 EEPS(0.103)QNDIS(0.897)PK;EEPS(0.373)QNDIS(0.627)PK 130.61 0.00020032 17672500.0 50992.0 92894.0 96946.0 115368.0 105922.0 101747.0 107150.0 104067.0 98243.0 100614.0 True False 50264.84472921245 92678.90965039056 88975.47410238218 123852.54757636617 99691.87621066427 97395.5179938414 112697.70271102352 108902.33273526152 87177.83879534662 118004.99584027233 0.42595522648252354 0.785381237382845 0.7539975190780605 1.0495534252126824 0.8448106412850851 0.8253508023141051 0.955024843724137 0.9228620530834823 0.7387639665133132 1.0 16.848488413018984 -4.535631090788166 1.41595763922947 0.8926851777823589 1.2093639049466687e-21 0.6882889288193711 0.09358036395815665 1.2384478272780695 1.4565981080031019 0.025943067766297352 1.8560471163427745 2.913190662158616e-05 4.535631090788166 -0.8926851777823589 EEPVAIES(ph)PGQDLLGESR ddPTM_PC-9_AZD4547_30min_R2 2 EEPVAIESPGQDLLGESR 18 0 Q96RG2-4;Q96RG2;Q96RG2-2 Q96RG2-4 PASK PAS domain-containing serine/threonine-protein kinase 1 EEPVAIES(1)PGQDLLGESR;EEPVAIES(0.986)PGQDLLGES(0.014)R 168.99 9.0804e-08 4340000.0 20867.9 21616.0 25744.6 31132.6 25195.4 24378.4 18646.4 29575.0 21106.8 23006.0 True False 27503.45812071563 28602.949276081123 25403.20978277719 23955.460063875194 21697.45361426125 22854.014794189945 20305.893477136822 25004.863315890118 22222.46235761378 22200.566942481404 1.2388628719245451 1.288388235768366 1.144259506912296 1.079047220998476 0.9773378162132682 1.0294338362349724 0.9146565279051918 1.1263164305972122 1.000986254773993 1.0 14.438308899127646 -5.626420887316513 1.808608814049618 1.0115578916838126 1.2676123578500533 0.7819665118031862 0.052831702630819176 0.15639187972695 1.0208643755530882 0.015769994563463993 0.038200604158815064 2.3636279271142867e-06 5.626420887316513 0.2560544661662407 EEPVAIES(ph)PGQDLLGESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEPVAIESPGQDLLGESR 18 0 Q96RG2-4;Q96RG2;Q96RG2-2 Q96RG2-4 PASK PAS domain-containing serine/threonine-protein kinase 1 EEPVAIES(1)PGQDLLGESR 128.59 4.2443e-05 1550100.0 9558.9 11807.0 12324.0 11263.0 13434.0 12999.0 13182.0 8763.5 9516.3 8430.3 True False 11177.032973119178 12979.120930255393 12617.850899030267 10631.97062513867 10801.70413677591 12317.30955656834 11933.305530584586 8533.467410695777 9655.457884429163 9958.646655781922 1.1223445674347596 1.3033016813303446 1.2670246605952655 1.0676119951465315 1.0846558282600092 1.2368457263635309 1.1982858658466602 0.8568902688942482 0.9695552235326343 1.0 13.281733983215245 -7.752263865462857 24.957203929510356 0.9349170555021439 1.1846019897761058 0.6589953479701548 0.07929404822016944 111.79913267972579 304093.3683962051 0.04022151225670257 0.022804805689921905 1.7690338151182606e-08 7.752263865462857 0.24968493427396188 EEPVAIES(ph)PGQDLLGESR ddPTM_PC-9_Lapatinib_30min_R1 1 EEPVAIESPGQDLLGESR 18 0 Q96RG2-4;Q96RG2;Q96RG2-2 Q96RG2-4 PASK PAS domain-containing serine/threonine-protein kinase 1 EEPVAIES(1)PGQDLLGESR 169.62 1.0448e-24 0.0 6176.7 5188.8 7500.8 5617.4 6712.5 6460.9 5705.6 3925.5 6103.9 4137.8 True False 6088.619125331944 5176.785652398922 6884.113177925309 6030.522335097068 6317.683947282762 6184.582368093509 6001.00805028479 4107.893060742306 5416.414505083475 4853.013216728068 1.2546059228408468 1.0667157539474297 1.4185234761356413 1.2426346407444742 1.3018064582033395 1.2743798732662825 1.2365529996085005 0.846462368283405 1.1160930875715305 1.0 12.244665073814698 -7.680051165224595 8.00897977672595 0.9868225555276582 1.2584715033057403 0.5993966576604886 0.10081554651487572 0.15870976384379748 13.574011233098869 0.046232085160635206 0.02651622051582097 2.0890500006049676e-08 7.680051165224595 0.27164894777808213 EEPVLT(ph)LVDEAIVK ddPTM_PC-9_AZD4547_30min_R2 2 EEPVLTLVDEAIVK 14 0 Q02156 Q02156 PRKCE Protein kinase C epsilon type 1 EEPVLT(1)LVDEAIVK;EEPVLT(1)LVDEAIVK 171.76 2.9123e-19 0.0 1077.29 1372.74 778.65 0.0 0.0 586.12 1803.88 0.0 827.73 790.8 True False 1419.8458109759847 1816.4513596061977 768.3245922391277 0.0 0.0 549.4698237444052 1964.4218254213968 0.0 871.4821179557131 763.1143327007867 1.860593819475147 2.3803135149846795 1.006827626366158 0.0 0.0 0.7200360420433219 2.574216917757246 0.0 1.1420072728438935 1.0 9.575755413103611 -10.03992492077708 9.769807291180474 1.0000557793207803 1.0509817553376173 0.0 0.9042283025870332 0.0 0.0 0.9356558554897921 0.22692987773012163 9.121685180439721e-11 10.03992492077708 0.050925976016837016 EEPVLT(ph)LVDEAIVK ddPTM_PC-9_Lapatinib_30min_R1 2 EEPVLTLVDEAIVK 14 0 Q02156 Q02156 PRKCE Protein kinase C epsilon type 1 EEPVLT(1)LVDEAIVK;EEPVLT(1)LVDEAIVK 202.63 1.5602e-08 3715200.0 21952.9 27736.0 16148.400000000001 16150.5 15616.699999999999 21928.6 26958.0 20978.6 16618.9 9900.2 True False 21639.8476203312 27671.77899609476 14820.74088662664 17338.261646488627 14698.156409613506 20990.7648960633 28353.75333349295 21953.342342144566 14747.1044772247 11611.436378812718 1.8636667260062012 2.3831486556294794 1.2763916886002071 1.4932055846359884 1.265834469578036 1.8077664305481584 2.4418816422427967 1.890665515095327 1.2700499745348997 1.0 13.503258829652296 -10.24861518253086 9.451809914185487 1.0000086364234806 1.7540213543218615 0.22911281765989067 0.40880862254002287 0.0 0.0 0.4204416218180601 0.10197207153893276 5.641373023732423e-11 10.24861518253086 0.7540127178983809 EEPVS(ph)SGPEEAVGK ddPTM_PC-9_AZD4547_30min_R2 2 EEPVSSGPEEAVGK 14 0 O00567 O00567 NOP56 Nucleolar protein 56 1 EEPVS(0.912)S(0.088)GPEEAVGK;EEPVS(0.848)S(0.152)GPEEAVGK 299.64 5.008699999999998e-99 260120000.0 321090.0 373080.0 380490.0 403450.0 358750.0 412610.0 352860.0 423400.0 351600.0 380560.0 True False 423189.94091310404 493670.8140229618 375444.4539922504 310440.83574036363 308943.75497575896 386809.4314733827 384263.8564196042 357973.25876408716 370184.85819437384 367236.7102334485 1.1523628469607157 1.3442850354180018 1.0223500089454138 0.8453426008064926 0.8412659910262421 1.053297289444435 1.04636558849286 0.9747752574532306 1.0080279228050246 1.0 18.48635075711158 -5.389054635306073 5.380527307244315 0.9654859341119068 1.2453954189919318 0.6489283251552502 0.08140405797561182 0.13357109554144184 5.22706518095834 0.022799920307195756 0.048659842973872304 4.082680219880027e-06 5.389054635306073 0.2799094848800251 EEPVS(ph)SGPEEAVGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EEPVSSGPEEAVGK 14 0 O00567 O00567 NOP56 Nucleolar protein 56 1 EEPVS(0.5)S(0.5)GPEEAVGK;EEPVS(0.983)S(0.017)GPEEAVGK 283.82 1.3521999999999997e-83 136957000.0 108239.0 128722.0 105564.0 135524.0 133807.0 122962.0 128171.0 102671.0 118007.0 105608.0 True False 126561.72488230318 141500.66946593838 108081.04611369933 127931.02965473644 107588.4788915866 116513.65625777029 116029.71500231819 99975.99503891646 119732.6291276895 124753.89440753222 1.0144911746711918 1.134238495222439 0.8663540855937701 1.025467222985645 0.8624057742047592 0.9339480487651661 0.9300688812429787 0.8013857644581894 0.9597506330067758 1.0 16.928725326911078 -5.263363871572063 24.99943698280756 0.9175506032217857 1.0743648383871833 0.4389194212701185 0.06853929655741586 131.5211683467339 1708505.4701130772 0.01688886722450512 0.0382749392229928 5.453007919588994e-06 5.263363871572063 0.1568142351653976 EEPVS(ph)SGPEEAVGK ddPTM_PC-9_Lapatinib_30min_R1 2 EEPVSSGPEEAVGK 14 0 O00567 O00567 NOP56 Nucleolar protein 56 1 EEPVS(0.589)S(0.411)GPEEAVGK;EEPVS(0.821)S(0.179)GPEEAVGK 288.29 6.393599999999998e-84 138100000.0 215660.0 233830.0 218408.0 193745.0 213755.0 219413.0 198631.0 200064.0 224796.0 153335.8 True False 212584.64885280005 233288.5810014729 200451.33731926038 207993.6536143735 201182.35115849948 210029.21746668417 208915.14127105256 209359.7038095402 199477.10727317695 179839.68872288938 1.1820786076891325 1.297202984825789 1.1146112337201106 1.1565503426491461 1.1186760419080601 1.1678691114190767 1.1616742819932526 1.164146275476141 1.1091940199059531 1.0 17.45635191800902 -14.522878745268937 0.10459866370091064 0.47719287105546726 1.2670880638575306 0.5895136528416776 0.04517523165808217 131.87138861837104 0.9253449759482434 14.91256017972726 0.6866441581325643 3.000000000078754e-15 14.522878745268937 0.7898951928020633 EEPVSS(ph)GPEEAVGK ddPTM_PC-9_AZD4547_30min_R2 2 EEPVSSGPEEAVGK 14 0 O00567 O00567 NOP56 Nucleolar protein 56 1 EEPVS(0.011)S(0.989)GPEEAVGK;EEPVS(0.003)S(0.997)GPEEAVGK 196.33 1.1422e-07 22956000.0 77194.0 85955.0 80308.0 112618.0 90423.0 91358.0 94318.0 106616.0 77451.0 92179.0 True False 101740.08626505415 113738.27280836205 79243.06344768494 86655.66003075543 77869.32726459356 85645.3698178555 102712.11928182324 90140.94699195068 81544.90174064977 88951.8412671038 1.1437659391394712 1.2786500109292822 0.89085354860429 0.9741862427619299 0.8754099539184157 0.9628285215668595 1.1546935714731323 1.0133679720161863 0.916730902689102 1.0 16.440736848554266 -5.258723692112401 24.999941236575268 0.9765963702392698 1.2112079858798421 0.5849684292160491 0.08005318841564314 168.28701830722275 1549185.2479561132 0.02182932433522362 0.05265405424537856 5.511582441139835e-06 5.258723692112401 0.2346116156405723 EEPVSS(ph)GPEEAVGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EEPVSSGPEEAVGK 14 0 O00567 O00567 NOP56 Nucleolar protein 56 1 EEPVS(0.181)S(0.819)GPEEAVGK;EEPVS(0.267)S(0.733)GPEEAVGK 250.05 1.9138999999999998e-35 120908000.0 74802.0 89023.0 83479.0 84224.0 98051.0 75803.0 96474.0 77791.0 72630.0 73717.0 True False 87464.50119315629 97860.61510748939 85469.45595587051 79505.2023378921 78838.610414993 71827.75723644503 87335.28430872539 75749.0686763776 73692.0763475396 87081.30855654892 1.0044004005332388 1.1237843887467607 0.9814902574686082 0.9129996282297821 0.9053448061566133 0.8248355293122573 1.0029165357800238 0.869865989980934 0.8462444762148399 1.0 16.41007546638034 -5.5628198292503965 3.2082872214918803 0.9036436616199156 1.064187130885245 0.5049683424285096 0.06117106064204257 0.17721302658242766 3.7290657162419416 0.016433354055204175 0.03316814280708448 2.7364037111517673e-06 5.5628198292503965 0.16054346926532947 EEPVSS(ph)GPEEAVGK ddPTM_PC-9_Lapatinib_30min_R1 3 EEPVSSGPEEAVGK 14 0 O00567 O00567 NOP56 Nucleolar protein 56 1 EEPVS(0.086)S(0.914)GPEEAVGK;EEPVS(0.151)S(0.849)GPEEAVGK;EEPVS(0.029)S(0.971)GPEEAVGK 201.3 2.9076e-08 147760400.0 262411.0 298596.0 282007.0 242608.0 268056.0 292244.0 268960.0 286148.0 292040.0 216715.0 True False 258668.97101971565 297904.61930768396 258821.47303850093 260450.20163656247 252289.47309837278 279745.4053740377 282885.43276861275 299443.4807146321 259147.37988246494 254173.8989954145 1.0176850260473922 1.1720503973268255 1.0182850169173754 1.024692947096276 0.9925860762867877 1.1006063426641794 1.112960197277047 1.178104761732574 1.019567236866993 1.0 17.9554563626741 EEPVSSGPEEAVGKS(ph)SSK ddPTM_PC-9_Lapatinib_30min_R1 1 EEPVSSGPEEAVGKSSSK 18 1 O00567 O00567 NOP56 Nucleolar protein 56 1 EEPVS(0.006)S(0.008)GPEEAVGKS(0.437)S(0.437)S(0.112)K 66.536 0.0065423 7376200.0 12974.0 17045.0 21545.0 11224.0 17461.0 12272.0 14325.0 16876.0 15199.0 9331.6 True False 12788.988380859792 17005.533349741683 19773.653266105062 12049.450402166389 16433.978309646824 11747.155167429237 15066.67840723668 17660.12056886693 13487.128567434554 10944.554626424591 1.168525245420402 1.5537894350386294 1.8067115511821237 1.1009539276339424 1.5015666576297713 1.073333321309105 1.3766369597954777 1.6135988326311825 1.2323140619053752 1.0 13.417925626775297 -12.941923383245344 0.2673062007578784 4.711719071510739e-13 1.42551088533868 0.2056719045294383 0.2273312997203411 132.11549356417908 2.773377193107726 73.39569586010066 0.2937932121694595 1.1430799752823873e-13 12.941923383245344 1.4255108853382088 EEQERLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEQERLER 8 1 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 0 110.12 0.0048831000000000005 17059000.0 30607.0 10688.0 19774.0 29935.0 35868.0 35014.0 28038.0 47730.0 34903.0 20695.0 False True 35788.1605841947 11749.034005468755 20245.487153312606 28257.839000579457 28839.922880592385 33177.80420137578 25382.0376624587 46477.1380741153 35413.390345011314 24446.839678470136 1.463917670131925 0.48059520821482316 0.8281433273006007 1.1558892426273648 1.179699431906168 1.357140826288268 1.0382543509217748 1.9011511788596063 1.4485876624862561 1.0 14.57736035495645 -6.416019468213283 1.1586280596680145 1.4159262170567672 0.8942643587996845 0.21660647200839833 0.3275982329820656 0.6144306389689524 1.7236455230306498 0.1443023501988907 0.182452885608306 3.8369004534957523e-07 6.416019468213283 -0.5216618582570828 EEQRS(ph)PFNDRFPLK ddPTM_PC-9_Lapatinib_30min_R1 1 EEQRSPFNDRFPLK 14 2 E9PQ01;O94913;E9PKN0 E9PQ01 PCF11 Pre-mRNA cleavage complex 2 protein Pcf11 1 EEQRS(1)PFNDRFPLK 51.726000000000006 0.030143 11459000.0 55665.0 58847.0 75933.0 69451.0 80797.0 68294.0 71073.0 68161.0 75973.0 58819.0 True False 54871.20689228921 58710.74338704893 69690.0818498564 74558.65822174429 76044.67931301385 65373.22482108962 74752.81217714025 71328.00889396417 67416.12070884305 68985.78577860897 0.795398737188895 0.8510556591391888 1.0102092925853983 1.0807829088302325 1.1023238838948428 0.9476332563767139 1.0835973140472586 1.0339522568152217 0.9772465435879308 1.0 16.07401151101659 -5.22125803418479 3.0439058307683764 1.0361604413142755 0.8050785946115472 0.7642301438734179 0.04636029446876679 0.1167359770408321 2.1419510444393803 0.012416090681511319 0.0392079946022502 6.0081665880069015e-06 5.22125803418479 -0.23108184670272836 EEQSQITSQVT(ph)GQIGWR ddPTM_PC-9_Lapatinib_30min_R1 1 EEQSQITSQVTGQIGWR 17 0 A0A087WY71;E9PFW3;Q96CW1-2;Q96CW1 A0A087WY71 AP2M1 AP-2 complex subunit mu 1 EEQSQIT(0.003)S(0.003)QVT(0.994)GQIGWR 159.88 1.4981e-17 0.0 6218.2 7559.1 6106.0 7129.0 5013.1 6816.2 6497.8 8088.5 6479.6 4265.1 True False 6129.52732772178 7541.597368379724 5603.988249841608 7653.290441646844 4718.239314133813 6524.687015338267 6834.224290020422 8464.321238520988 5749.799214787085 5002.316852111482 1.225337680305977 1.5076208867489889 1.1202785460253601 1.529949155143258 0.9432108068368841 1.304333013728267 1.366211795867287 1.6920801877930205 1.149427232375352 1.0 12.288380726925544 -7.006771054631018 24.947059628943766 1.3561273539227492 1.2692292218061685 0.0 0.23188874114502367 1401.310044601097 5162951.281684455 0.0806867750783678 0.06852827537883044 9.84529979904782e-08 7.006771054631018 -0.0868981321165807 EEQTDTS(ph)DGESVTHHIR ddPTM_PC-9_AZD4547_30min_R2 1 EEQTDTSDGESVTHHIR 17 0 A2AB27;P36915 A2AB27 GNL1 Guanine nucleotide-binding protein-like 1 1 EEQT(0.12)DT(0.045)S(0.835)DGESVTHHIR 84.113 0.001961 11983000.0 15366.0 9946.9 28674.0 42494.0 44058.0 33405.0 19434.0 40298.0 27516.0 26134.0 True False 20252.068367344877 13162.04090276884 28293.764024741242 32697.664825755386 37941.30719643753 31316.18006923815 21163.588351353428 34070.87005591685 28970.43958497264 25219.056614570516 0.803046231144272 0.5219085354352376 1.1219200010992596 1.2965459146819966 1.5044697260609117 1.2417665160061924 0.8391903263790602 1.3509970089932757 1.1487519151780932 1.0 14.62222668840604 -5.357453541742198 5.139934371697537 1.2107430597598146 0.6655906171790412 0.5635122167553912 0.1851810819171961 0.14692829893056777 6.0423686364536255 0.05024328066812219 0.10855566727727066 4.390828336160994e-06 5.357453541742198 -0.5451524425807733 EEQTDTS(ph)DGESVTHHIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEQTDTSDGESVTHHIR 17 0 A2AB27;P36915 A2AB27 GNL1 Guanine nucleotide-binding protein-like 1 1 EEQT(0.117)DT(0.087)S(0.797)DGESVTHHIR 82.56 0.0024796999999999996 7680900.0 24193.0 32444.0 39112.0 40229.0 39593.0 45541.0 31244.0 31119.0 40932.0 30564.0 True False 28288.39706646917 35664.82590507375 40044.57841308598 37975.09955417772 31835.035870728632 43152.74978965142 28284.342133028746 30302.159223305964 41530.553064263906 36105.01125550912 0.7835033443495397 0.9878081924051968 1.1091141373616313 1.051795809878975 0.881734550515368 1.1952011172151875 0.7833910349138293 0.8392784871014901 1.1502711568308104 1.0 15.139911471834148 -9.886528351839036 15.264368773927805 1.0000034457012732 0.976312259444346 0.0025704754990263368 0.14274360444180484 0.0 0.0 0.13620064447823826 0.03303350843888089 1.298588785911049e-10 9.886528351839036 -0.023691186256927232 EEQTDTS(ph)DGESVTHHIR ddPTM_PC-9_Lapatinib_30min_R1 1 EEQTDTSDGESVTHHIR 17 0 A2AB27;P36915 A2AB27 GNL1 Guanine nucleotide-binding protein-like 1 1 EEQT(0.001)DT(0.043)S(0.956)DGESVTHHIR 130.37 1.6029000000000002e-05 16430000.0 30891.0 28946.0 57481.0 25574.0 47597.0 41989.0 31905.0 40624.0 49867.0 30409.0 True False 30450.488675284407 28878.97731543695 52755.13406307661 27454.797272363074 44797.438039302455 40193.228351139674 33556.88478763604 42511.53934520326 44250.453337210245 35665.15513255448 0.8537882020170936 0.8097252684897693 1.4791785951022747 0.7697932946127256 1.2560561666648185 1.1269607044117986 0.9408871113252484 1.191962832832305 1.2407194970201958 1.0 15.122227628408139 EERS(ph)PQTLAPVGEDAMK ddPTM_PC-9_Lapatinib_30min_R1 4 EERSPQTLAPVGEDAMK 17 1 Q92797 Q92797 SYMPK Symplekin 1 EERS(0.974)PQT(0.026)LAPVGEDAMK;EERS(0.832)PQT(0.168)LAPVGEDAMK;EERS(0.953)PQT(0.047)LAPVGEDAMK;EERS(0.993)PQT(0.007)LAPVGEDAMK 119.51 0.00021287 45912200.0 155906.0 186414.0 192154.0 162517.0 164316.0 178161.0 173455.0 183439.0 168675.0 136683.0 True False 153682.75185034084 185982.3698362416 176355.83985588994 174469.04232081908 154651.25593768558 170541.46934357585 182435.65117816662 191962.24561699366 149677.04527350637 160308.47443135103 0.9586689187548377 1.1601530767226214 1.100103038728691 1.0883332458854633 0.9647104214937305 1.0638331501096463 1.1380287400607203 1.1974553828044676 0.9336814276627817 1.0 17.290491167533297 EES(ph)DGEYDEFGR ddPTM_PC-9_AZD4547_30min_R2 2 EESDGEYDEFGR 12 0 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 EES(1)DGEYDEFGR;EES(1)DGEYDEFGR 202.29 1.4192e-06 28821000.0 29329.0 31923.0 33819.0 20830.9 29667.0 38417.0 36224.0 39218.0 37401.0 24582.0 True False 38655.01191890264 42241.48546171062 33370.53796305794 16028.657839196787 25548.24913969567 36014.77891692625 39447.86582481357 33157.75923998576 39377.9405043452 23721.39166217849 1.6295423333250043 1.7807338651661262 1.4067698235539907 0.6757047844184016 1.077013081843336 1.5182405581350609 1.6629659164436568 1.397799914616842 1.6600181416476334 1.0 14.533901030463223 EES(ph)DGEYDEFGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EESDGEYDEFGR 12 0 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 EES(1)DGEYDEFGR 83.226 0.011254 19815000.0 7635.4 12229.0 10130.0 7502.4 9052.2 8704.0 13191.0 5185.8 5650.9 6307.8 True False 8927.922413975888 13443.014301354551 10371.537618238937 7082.064851108975 7278.4863917614175 8247.546917483713 11941.45298543023 5049.678244809282 5733.533722047511 7451.354207482678 1.1981610544041021 1.8041035128695164 1.391899690907701 0.9504399675426969 0.9768004833876148 1.1068520818942542 1.6025882883729479 0.6776859754886401 0.769461974615282 1.0 12.863286929146359 -5.650399686485244 4.763212525454012 1.026495911697987 1.521777768361331 0.3748367020998674 0.26877613213909096 0.22164193024897366 8.242506537468127 0.07641513332763411 0.13539759894563252 2.2366617640992044e-06 5.650399686485244 0.4952818566633439 EES(ph)DGEYDEFGR ddPTM_PC-9_Lapatinib_30min_R1 2 EESDGEYDEFGR 12 0 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 EES(1)DGEYDEFGR;EES(1)DGEYDEFGR 241.35 2.3538e-22 29413000.0 69830.0 57575.0 42968.0 39543.0 46062.0 42790.0 48376.0 49079.0 46316.0 43351.0 True False 68834.21139474626 57441.688624897455 39435.3369012765 42451.12413158104 43352.72372137632 40959.97144836187 50880.67257441412 51359.389511698275 41099.404350898025 50844.162588423475 1.3538272220539802 1.12975975413107 0.7756118872583299 0.8349262131666337 0.8526588208819698 0.8055983098773251 1.0007180762575676 1.0101334528300818 0.8083406680053337 1.0 15.633794527513125 -4.999831851410917 3.3999870312665106 0.8853709259473685 1.3398859158756886 0.7561276683259526 0.08519375799291 0.11679334704083069 2.74186212666316 0.02310843650223167 0.10470288444362612 1.0003872513971e-05 4.999831851410917 0.45451498992832007 EES(ph)DGEYDEFGRK ddPTM_PC-9_AZD4547_30min_R2 2 EESDGEYDEFGRK 13 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 EES(1)DGEYDEFGRK;EES(1)DGEYDEFGRK 115.24 0.00042958 20117200.0 41967.0 48774.0 31180.0 23782.6 35536.0 41144.0 51499.0 45055.0 44557.0 29290.0 True False 55311.63303217253 64539.241672445445 30766.532827349914 18299.889007507187 30602.439796009905 38571.25917583399 56082.311233217595 38092.7850109021 46912.192055081614 28264.566015182165 1.9569249003314673 2.283397581189767 1.088519555220619 0.6474498493158358 1.0827139457783277 1.3646506779943355 1.9841914856606422 1.347722267889794 1.6597527812697699 1.0 14.786706925028495 EES(ph)DGEYDEFGRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EESDGEYDEFGRK 13 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 EES(1)DGEYDEFGRK;EES(1)DGEYDEFGRK 92.939 0.0020029 15289500.0 30911.0 53620.0 41910.0 42214.0 49020.0 34149.0 46613.0 26277.0 33710.0 32576.0 True False 36143.62177992098 58943.03923776526 42909.29334456009 39848.88643963459 39414.882893014386 32358.16632412125 42197.47919110451 25587.256592782895 34202.944976945546 38481.77092852589 0.9392400845338518 1.5317132713887598 1.1150550587772494 1.0355263148790088 1.0242481554765661 0.8408699896951647 1.0965576212560486 0.6649188947230984 0.8888090166243227 1.0 15.231887572914493 -6.05265822824251 1.2701250723240631 0.8892175677677626 1.2418671004251582 0.34280578327278755 0.1736646775463458 0.4580969342660436 1.5022668805834396 0.06307301396240363 0.11201460049376433 8.858124332808979e-07 6.05265822824251 0.3526495326573956 EES(ph)DGEYDEFGRK ddPTM_PC-9_Lapatinib_30min_R1 2 EESDGEYDEFGRK 13 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 EES(1)DGEYDEFGRK;EES(1)DGEYDEFGRK 96.135 0.0015311 51969000.0 190080.0 164499.0 109950.0 101805.0 134788.0 113325.0 125816.0 127604.0 114150.0 111731.0 True False 187369.42434359688 164118.11267228876 100910.33541927353 109292.07931152462 126860.03484340383 108478.35392347768 132330.13685758394 133532.9476813045 101293.22494721055 131043.55447780082 1.4298255651737364 1.2523936284107042 0.7700518794792616 0.834013391555546 0.9680753498249646 0.827803811913956 1.0098179752900482 1.018996685593761 0.7729737288556984 1.0 16.999686869296596 -5.091587577214869 4.188781953774016 0.9033732315908033 1.397770246819462 0.7884449007214636 0.0931560082223494 0.09054227595966395 2.750505088478756 0.02427332552728669 0.0764940043098358 8.098646127828649e-06 5.091587577214869 0.49439701522865864 EES(ph)EDELEEANGNNPIDIEVDQNKESK ddPTM_PC-9_Lapatinib_30min_R1 1 EESEDELEEANGNNPIDIEVDQNKESK 27 1 Q9UKL0 Q9UKL0 RCOR1 REST corepressor 1 1 EES(1)EDELEEANGNNPIDIEVDQNKESK 68.434 0.0027478999999999997 0.0 3602.2 2871.3 3171.9 1911.9 2787.9 948.19 1978.6 2311.4 2720.9 0.0 True False 3550.8319674374256 2864.6516812621467 2911.118625888079 2052.507503911432 2623.9212032222867 907.6381240388472 2081.042226635846 2418.796082180554 2414.4435896527857 0.0 0.0 EES(ph)EEEEDEDDEEEEEEEKEK ddPTM_PC-9_Lapatinib_30min_R1 1 EESEEEEDEDDEEEEEEEKEK 21 1 H0Y8X0;B4DFG0;H0Y993;P35659;D6R9L5;A0A494C198;A0A494C028 H0Y8X0 DEK Protein DEK 1 EES(1)EEEEDEDDEEEEEEEKEK 116.92 1.4125e-06 50269000.0 50757.0 49480.0 37123.0 37806.0 38198.0 38339.0 43734.0 41614.0 26216.0 36730.0 True False 50033.1958723062 49365.43210004214 34070.890238924025 40586.37935711889 35951.26874015746 36699.33034257412 45998.33252789455 43547.538359375925 23263.27801328143 43078.731560351385 1.1614361440102274 1.145935135784659 0.7908981765443168 0.9421442527911755 0.8345479877881579 0.8519129745303663 1.0677736057166152 1.0108825580987166 0.5400177110760704 1.0 15.394688150357013 -5.246049084235354 23.025271499429117 0.8864926225667287 1.1536858530777774 0.37731721556663844 0.14053967141025236 300.6140019901981 449739.0285920054 0.03512412438207553 0.09195239933357387 5.67480464785145e-06 5.246049084235354 0.2671932305110487 EES(ph)EESEAEPVQR ddPTM_PC-9_AZD4547_30min_R2 1 EESEESEAEPVQR 13 0 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 EES(0.998)EES(0.002)EAEPVQR 122.1 0.0010770999999999999 0.0 3605.0 3182.5 4223.9 4013.6 4612.2 2980.1 2863.7 4456.5 2887.4 4340.0 True False 4751.3150113418105 4211.180887820511 4167.888326152766 3088.3265295018573 3971.87564236709 2793.753875896917 3118.563752278008 3767.8503251822276 3040.0220692560683 4188.057920993191 1.1344912369824731 1.005521166914004 0.99518402199279 0.7374125639526651 0.9483812586396051 0.6670762268814044 0.7446324313342939 0.8996652855003228 0.7258787071729734 1.0 12.032065679593607 -5.403829639410864 1.5031356254643105 0.8072219293457754 1.1135923189708778 0.4873109661312286 0.10636200807797018 0.38551392033425325 1.5398280685818162 0.030998226772687685 0.12264572715044443 3.946120660963617e-06 5.403829639410864 0.30637038962510244 EES(ph)EESEAEPVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EESEESEAEPVQR 13 0 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 EES(0.997)EES(0.003)EAEPVQR 120.87 0.0010583 0.0 3166.6 4776.5 3515.5 2549.7 4537.4 3379.7 3831.6 4277.2 3976.8 3142.9 True False 3702.6428367991266 5250.679353211219 3599.322852607994 2406.848575238931 3648.3290419984346 3202.4625823781844 3468.643109618262 4164.928032068004 4034.9531766335567 3712.6828908172897 0.9972957415665649 1.4142547337392888 0.9694668137454795 0.6482774441070297 0.982666483857799 0.8625736903894886 0.934268616960899 1.1218108722318483 1.0868025347958883 1.0 11.858246381060638 -5.422883103713962 9.330117748879045 0.9396794656311883 1.2043649345133687 0.30389026743621717 0.15431861676486094 0.4338859449426556 37.58757428412417 0.04115620263972933 0.08579758460412568 3.7767383331142794e-06 5.422883103713962 0.26468546888218036 EES(ph)EESEAEPVQR ddPTM_PC-9_Lapatinib_30min_R1 1 EESEESEAEPVQR 13 0 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 EES(1)EESEAEPVQR 132.06 6.0743000000000004e-05 2311800.0 2494.5 2780.9 3057.9 2253.6 2184.2 2667.9 2790.1 2367.4 2757.9 2962.9 True False 2458.927972564725 2774.460996907988 2806.491265835354 2419.3372617892182 2055.7296503024213 2553.800136178657 2934.557725935853 2477.398046618606 2447.2762600255114 3475.0333171839143 0.7075983877349938 0.7983983874883669 0.8076156426925049 0.6962054866713602 0.5915712059901447 0.7348994680281791 0.8444689469377376 0.7129134659998688 0.7042454090796249 1.0 11.762811094528617 -11.249065755032172 2.720248986238231 1.0477337073047428 0.7347006405812686 0.5846610424612515 0.06747426770993548 35364775.24906146 29130166.969878115 11451374.590246856 0.018622866879419442 5.6355232384923805e-12 11.249065755032172 -0.3130330667234742 EES(ph)PLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EESPLR 6 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 EES(1)PLR 87.696 0.039516 124700000.0 290310.0 411460.0 393070.0 319430.0 351280.0 274400.0 382260.0 261060.0 338650.0 249410.0 True False 339453.7491161362 452307.02955559344 402442.2795262756 301533.37270603277 282449.2056845801 260009.98094640742 346049.5654772616 254207.4516159336 343602.1155871443 294626.0586715257 1.1521511391312074 1.535190171551879 1.3659425827467375 1.0234443418401356 0.9586701426145018 0.8825084315990147 1.174538216468718 0.8628138758742512 1.166231246266717 1.0 18.16852551191706 -5.768723311630621 6.244861276080699 1.0022908115257487 1.3714697364378825 0.5927489748303771 0.12932778419920582 0.09010053473290713 13.92113852924568 0.0341013576397346 0.05444556712170002 1.703243296574271e-06 5.768723311630621 0.3691789249121338 EES(ph)PPPPK ddPTM_PC-9_Lapatinib_30min_R1 1 EESPPPPK 8 0 E9PGM9;P78332;P78332-2 E9PGM9 RBM6 RNA-binding protein 6 1 EES(1)PPPPK 68.735 0.042785000000000004 3625300.0 56118.0 51433.0 64292.0 48206.0 57516.0 50033.0 38116.0 39973.0 48583.0 41864.0 True False 55317.74702921916 51313.91004853409 59006.15993429689 51751.23005050188 54133.02196080677 47893.20522261952 40089.45997697964 41830.29150861089 43111.07093832969 49100.13661972644 1.1266312242193381 1.0450869097565452 1.2017514409642316 1.0539936059915225 1.102502471226492 0.9754189808787207 0.8164836747291926 0.8519383934220088 0.8780234416091097 1.0 15.58343941835271 -6.929295465800417 3.061828780910577 0.8747758075638211 1.1060332462293232 0.7464117465470755 0.06022062747927765 0.11748472252795054 2.230908127221603 0.022261993778452085 0.018876988265636423 1.1768050792562314e-07 6.929295465800417 0.23125743866550208 EES(ph)SEDENEVSNILR ddPTM_PC-9_AZD4547_30min_R2 1 EESSEDENEVSNILR 15 0 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 EES(0.927)S(0.073)EDENEVSNILR 282.52 6.813899999999999e-89 5545700.0 25039.0 27649.0 31589.0 28076.0 33307.0 37747.0 31266.0 34221.0 28831.0 30820.0 True False 33000.88115644593 36585.99854433598 31170.10922011406 21603.511969875944 28682.897970669233 35386.67412284184 34048.613429732264 28932.930770349132 30354.947800346952 29741.001180877905 1.1096089521580725 1.2301535621423225 1.0480517797818791 0.7263881884301194 0.9644227440840497 1.1898279384620665 1.1448374996744883 0.9728297509013138 1.0206431053122644 1.0 14.860165593663913 -5.433955528857328 6.6333103224435375 1.0045239652521218 1.1655065863325036 0.2340765993320003 0.11905348479424875 0.3898113393686024 24.392416223841572 0.03465050199350961 0.07264554079819686 3.681666714605076e-06 5.433955528857328 0.16098262108038175 EES(ph)WESGR ddPTM_PC-9_AZD4547_30min_R2 1 EESWESGR 8 0 Q9NQ29-3;Q9NQ29;B8ZZ08 Q9NQ29-3 LUC7L Putative RNA-binding protein Luc7-like 1 1 EES(0.975)WES(0.025)GR 88.134 0.011204 6704000.0 24275.0 28541.0 38625.0 34702.0 36148.0 31907.0 32368.0 43175.0 21254.0 35438.0 True False 31993.945048633148 37766.32010032526 38112.807262873335 26701.990040555473 31129.47415989885 29911.850246046426 35248.689294875396 36503.29581279989 22377.44304909901 34197.32640648769 0.9355686075670367 1.1043646994918435 1.1144966951464026 0.7808209835810365 0.9102897048113437 0.874683882900616 1.0307440083441215 1.0674312774894217 0.6543623552060405 1.0 15.061595917208066 -5.742972625567446 24.96826481683084 0.9099227004788122 1.0567654804746178 0.23376361052234662 0.12289354823729723 364.35864352888905 492633.00445673306 0.03304735711516077 0.057103414578427915 1.8072880393287966e-06 5.742972625567446 0.14684277999580564 EES(ph)WESGR ddPTM_PC-9_Lapatinib_30min_R1 2 EESWESGR 8 0 Q9NQ29-3;Q9NQ29;B8ZZ08 Q9NQ29-3 LUC7L Putative RNA-binding protein Luc7-like 1 1 EES(0.999)WES(0.001)GR;EES(0.976)WES(0.024)GR 106.88 0.003819 15059700.0 54774.0 56067.0 56541.0 49941.0 51086.0 58162.0 53185.0 54932.0 58735.0 44848.0 True False 53992.91271567858 55937.18030624622 51892.417234571636 53613.82773829219 48081.22191894037 55674.54684224407 55938.6590637964 57484.34125912525 52119.64579303034 52599.91704379637 1.0264828492167082 1.0634461696901754 0.9865494120715885 1.0192758991169435 0.9140931130919163 1.0584531301805602 1.0634742829959234 1.0928599224075193 0.9908693534560873 1.0 15.682772903770488 EES(ph)WGPPR ddPTM_PC-9_AZD4547_30min_R2 1 EESWGPPR 8 0 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 EES(1)WGPPR 81.525 0.017759999999999998 3165000.0 15015.0 14948.0 23660.0 29612.0 29331.0 31576.0 23480.0 30452.0 27521.0 25777.0 True False 19789.45766859843 19779.648675928038 23346.25294083063 22785.410900839397 25258.896939913506 29601.547728371912 25569.674513212845 25746.343117345277 28975.70387476494 24874.55507590816 0.7955703170652962 0.7951759786483695 0.9385596192408787 0.9160128022916009 1.0154512055726213 1.1900332543854022 1.0279449998274717 1.0350473823060045 1.1648732524598553 1.0 14.602383100360651 -5.809020727866333 1.0405074653005184 1.0836913948639098 0.7825100141024286 0.7459484757580093 0.06348540011737945 0.2976461012572211 0.6240296852725724 0.02489178878897117 0.06795372343293572 1.5523129199018888e-06 5.809020727866333 -0.30118138076148115 EES(ph)WGPPR ddPTM_PC-9_Lapatinib_30min_R1 2 EESWGPPR 8 0 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 EES(1)WGPPR;EES(1)WGPPR 100.25 0.0049517 8370900.0 46499.0 53373.0 63097.0 48821.0 51405.0 52150.0 45156.0 50962.0 48963.0 38605.0 True False 45835.915733127724 53249.41809772735 57909.40822146349 52411.45920208176 48381.45896611851 49919.666067587605 47493.956729995116 53329.88056592773 43448.27133675231 45277.82281207096 1.012325966364884 1.1760595980673165 1.2789795229735512 1.1575525488409524 1.068546497187584 1.1025191355773216 1.0489452403027943 1.1778366814870371 0.9595927683424103 1.0 15.466516967274343 -6.2427169288190045 5.898757378264523 1.0698959252175075 1.1669864120667843 0.24230181268344608 0.08173121347452544 0.26086200290834255 34.49168410046942 0.024619893682734036 0.030794381626779346 5.718512452842035e-07 6.2427169288190045 0.09709048684927679 EES(ph)YSPSKDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EESYSPSKDR 10 1 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 EES(1)YSPSKDR 115.29 0.0054865 40048000.0 30033.0 35659.0 26602.0 25111.0 41197.0 28824.0 33043.0 29437.0 27469.0 25805.0 True False 35116.99372121143 39198.98985787896 27236.29256864681 23704.112080960414 33124.743585138975 27312.41869824801 29912.927829396645 28664.30994107966 27870.682158757587 30483.242227732382 1.1520097980018495 1.2859193115034644 0.8934841105539741 0.7776112496129235 1.0866542127531127 0.8959814213397652 0.9812908878237077 0.9403300911017289 0.9142952035922872 1.0 14.89572873701021 -5.264676910520813 24.99995194194772 0.933957473095589 1.2189645660110264 0.6567578697091834 0.08175321908571795 146.79358452381018 1133538.1162877 0.020847949047472482 0.04656815163655643 5.436546280650883e-06 5.264676910520813 0.28500709291543747 EESDWPAS(ph)GSSSPLRGESAADSDGWDSAPSDLR ddPTM_PC-9_Lapatinib_30min_R1 2 EESDWPASGSSSPLRGESAADSDGWDSAPSDLR 33 1 A0A087WVQ2;I3L0Y2;I3L4Q4;Q9BUL5-2;Q9BUL5-4;Q9BUL5 A0A087WVQ2 PHF23 PHD finger protein 23 1 EES(0.003)DWPAS(0.242)GS(0.242)S(0.242)S(0.242)PLRGES(0.019)AADS(0.011)DGWDSAPSDLR;EES(0.01)DWPAS(0.236)GS(0.236)S(0.236)S(0.236)PLRGES(0.031)AADS(0.011)DGWDS(0.001)APS(0.001)DLR 56.00899999999999 0.00052008 4722100.0 4582.799999999999 7025.700000000001 5998.1 3318.4 7205.4 6710.9 7494.1 6336.2 7393.6 5563.299999999999 True False 4517.448431617407 7009.432423307723 5504.959371335563 3562.4462058578915 6781.592538361442 6423.890450871976 7882.107829087081 6630.60298343533 6560.854909940395 6524.908992368717 0.6923389179681803 1.0742575002204147 0.8436837016077853 0.5459763822030915 1.0393390231638375 0.9845180152527969 1.2080027228434438 1.0161985387367438 1.005509029721904 1.0 12.671742064172353 -6.46868410500897 24.957647066636486 1.0494860530887284 0.8107514634451825 0.4447377348601391 0.13765414105198065 314.1873653921204 144688.97781654482 0.043597785893815286 0.04943496443727272 3.3987239742143177e-07 6.46868410500897 -0.238734589643546 EESDWPASGS(ph)SSPLR ddPTM_PC-9_AZD4547_30min_R2 1 EESDWPASGSSSPLR 15 0 A0A087WVQ2;I3L0Y2;I3L4Q4;Q9BUL5-2;Q9BUL5-4;Q9BUL5 A0A087WVQ2 PHF23 PHD finger protein 23 1 EESDWPAS(0.014)GS(0.404)S(0.291)S(0.291)PLR 98.654 0.011519 0.0 5436.2 7990.6 6956.6 4149.3 6021.8 7701.9 7674.1 10757.0 12102.0 6086.7 True False 7164.7985200156345 10573.405185300411 6864.350938638309 3192.742991045955 5185.777013834204 7220.298975460715 8357.080033298413 9094.752821268978 12741.687013277337 5873.606485647288 1.2198295097779357 1.8001555281474042 1.16867736294762 0.5435745480817832 0.8828948664685216 1.2292786370868047 1.422819191874656 1.5484103069371205 2.1693123372178325 1.0 12.520030897239632 -7.449532947485103 2.2892240300194864 1.639769053757679 1.1300703128282021 0.19647339726282287 0.39558003886308457 0.49828483281526964 5.1305911053464115 0.22668394177025247 0.12790273187941223 3.551951707958767e-08 7.449532947485103 -0.5096987409294769 EESDWPASGSS(ph)SPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EESDWPASGSSSPLR 15 0 A0A087WVQ2;I3L0Y2;I3L4Q4;Q9BUL5-2;Q9BUL5-4;Q9BUL5 A0A087WVQ2 PHF23 PHD finger protein 23 1 EESDWPAS(0.002)GS(0.125)S(0.436)S(0.436)PLR 104.09 0.0060581 0.0 5420.8 13165.0 11363.0 5712.5 6090.2 5957.7 8151.0 5063.4 5180.4 4919.7 True False 6338.434374319684 14471.934195546057 11633.93701441747 5392.447145174879 4896.869028866507 5645.267724068558 7378.87827187035 4930.491115115763 5256.1535496460665 5811.602665676231 1.0906517081346532 2.4901795645835194 2.0018465961426424 0.9278760877826496 0.8426021719942743 0.9713788173114347 1.2696804472629502 0.848387510081448 0.9044241067424157 1.0 12.504720355173493 -5.762827851287807 24.999956681404562 0.9677122604566262 1.9238214705893992 0.5922587905156745 0.33893147864364814 22.55013538933282 406037.5677307219 0.09110299616189374 0.14387443753168616 1.726522127397683e-06 5.762827851287807 0.9561092101327731 EESGKPGAHVTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EESGKPGAHVTVK 13 1 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ; 68.515 0.014708 22365400.0 124268.0 184436.0 279760.0 334850.0 386260.0 354390.0 299590.0 256900.0 315910.0 291070.0 False True 145304.1179951223 202745.5871849393 286430.53939570877 316089.44009834697 310575.1257906112 335805.1645320607 271210.66635623074 250156.64720804957 320529.5861069965 343838.68689114746 0.42259386024564105 0.5896532150529197 0.8330375560280889 0.9192957399770859 0.9032582360022017 0.9766357810643046 0.7887729819131455 0.7275407240234262 0.9322091967169182 1.0 18.39137235271985 -5.1089806472689565 2.1291507602571027 0.8819996037915026 0.4132675323309413 0.8019332896253222 0.07783326281860173 0.17376378636153017 1.34336515622056 0.022562775587432686 0.11938067575759438 7.780712221402426e-06 5.1089806472689565 -0.46873207146056123 EESGKPGAHVTVK ddPTM_PC-9_Lapatinib_30min_R1 4 EESGKPGAHVTVK 13 1 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;;; 95.273 0.0016028 66834200.0 540416.0 550746.0 779080.0 674390.0 797630.0 799010.0 738080.0 671740.0 766970.0 610030.0 False True 532709.5687398433 549470.7814747337 715027.0497357697 723986.8902990903 750714.9716009166 764838.2048832825 776294.1709468241 702951.4927074336 680585.7620478502 715472.8726861196 0.74455592808135 0.7679826901219055 0.999376883502688 1.0118998468537406 1.0492570721549324 1.0689967909081295 1.08500853153574 0.9824991548153648 0.9512390868052176 1.0 19.448537542320786 -5.267413761077813 3.6833686995082244 1.0253536330193864 0.7464742308548125 0.8861668093361702 0.03769411700218088 0.07043120179145929 2.1264349532845888 0.01111256137101703 0.02956278682954956 5.402393807752722e-06 5.267413761077813 -0.27887940216457396 EESHSNDQS(ph)PQIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EESHSNDQSPQIR 13 0 B5MBZ0;Q9HC35 B5MBZ0 EML4 Echinoderm microtubule-associated protein-like 4 1 EES(0.001)HS(0.021)NDQS(0.979)PQIR 121.18 0.0010630000000000001 0.0 5721.5 6759.7 6209.8 3206.4 4584.8 4796.6 4784.7 4696.1 4330.7 3575.0 True False 6690.036945223968 7430.758342699021 6357.865182797641 3026.7558032890574 3686.4413522621862 4545.057852068289 4331.458577771816 4572.832350929246 4394.028294620531 4223.119200315572 1.584145894987775 1.759542648510551 1.5054903452222117 0.716710956930338 0.8729190859653494 1.0762324330624293 1.0256538762742353 1.0828092066611668 1.0404698721959322 1.0 12.044093253391912 -5.622971264969738 5.624640283955774 0.9811217721625428 1.66227053533654 0.8756906744895121 0.11194683206691262 0.06731917112790715 3.146607352148095 0.032901968384419514 0.05786741723296738 2.382477100389336e-06 5.622971264969738 0.6811487631739971 EESHSNDQS(ph)PQIR ddPTM_PC-9_Lapatinib_30min_R1 1 EESHSNDQSPQIR 13 0 B5MBZ0;Q9HC35 B5MBZ0 EML4 Echinoderm microtubule-associated protein-like 4 1 EESHSNDQS(1)PQIR 99.796 0.0013694 4766900.0 12855.0 13944.0 15358.0 16261.0 13164.0 13329.0 15792.0 14772.0 12095.0 10094.0 True False 12671.685342681714 13911.713524716808 14095.324523594409 17456.888185105814 12389.719401419781 12758.949741416578 16609.632489150554 15458.361047837301 10732.73373400362 11838.73445059044 1.070358102512362 1.1751014082441034 1.1906107517169138 1.4745569518399981 1.0465408657596726 1.0777291943380185 1.402990544172749 1.305744386138025 0.906577791637884 1.0 13.53122724603642 -8.266573063867591 24.979685861672955 0.9532888615558095 1.2199475456742135 0.37643657613228343 0.13623524594235673 493.17579571908584 2399672.9820774114 0.12183161643507316 0.03523896659318105 5.412861765242001e-09 8.266573063867591 0.266658684118404 EESLVEELS(ph)PASEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EESLVEELSPASEK 14 0 A0A087WTL4;A0A087WX97;Q9BXK5-4;Q9BXK5 A0A087WTL4 BCL2L13 Bcl-2-like protein 13 1 EESLVEELS(0.932)PAS(0.068)EK 151.38 2.4678e-08 0.0 5065.5 6433.1 5605.6 3854.9 5904.3 4917.0 5792.2 3592.5 3713.4 3462.2 True False 5922.989101814557 7071.735653123229 5739.258763356383 3638.9224507544263 4747.394799372191 4659.1438641162 5243.520884103479 3498.2006815683894 3767.7014499373977 4089.869453239879 1.4482098192944846 1.7290859119039117 1.403286542266014 0.889740489851522 1.1607692748264713 1.1391913403068057 1.2820753679435195 0.8553330910836808 0.9212278027487482 1.0 11.997839078398977 -5.58694990792845 4.927414447003812 1.050989351666674 1.5856340699680207 0.7263977864237556 0.14081000139519098 0.10162622959983685 4.834995136117787 0.03997675267120146 0.07196884500783533 2.5885114601016413e-06 5.58694990792845 0.5346447183013467 EESREPAPAS(ph)PAPAGVEIR ddPTM_PC-9_Lapatinib_30min_R1 1 EESREPAPASPAPAGVEIR 19 1 Q14195-2 Q14195-2 1 EES(0.01)REPAPAS(0.99)PAPAGVEIR 57.802 0.012091 6090900.0 12557.0 12180.0 12763.0 11400.0 12176.0 13477.0 14429.0 14663.0 15071.0 12883.0 True False 12377.934877328227 12151.797958336965 11713.675406604727 12238.394029285182 11459.831618937043 12900.620126421436 15176.06301836077 15344.296509913243 13373.545275334302 15109.809384481545 0.8191986121308006 0.8042323797160148 0.7752364777437364 0.8099634957575682 0.7584365445871744 0.8537910570646214 1.004384809377362 1.0155188672116888 0.8850902705013297 1.0 13.883197840065574 -7.09939627576494 3.869908864235753 0.9767353312424496 0.7944470067030976 0.8396962102913231 0.03766456711780359 0.08871871540954636 2.385677726817092 0.01471429617019738 0.011343000720516104 7.954332192487923e-08 7.09939627576494 -0.18228832453935195 EESS(ph)EDENEVSNILR ddPTM_PC-9_AZD4547_30min_R2 1 EESSEDENEVSNILR 15 0 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 EES(0.049)S(0.951)EDENEVSNILR 200.0 8.2771e-50 0.0 9001.1 11962.0 15375.0 15475.0 10894.0 14938.0 11757.0 14133.0 14719.0 13523.0 True False 11863.262565489262 15828.48257034059 15171.117454153462 11907.477836366657 9381.556144127982 14003.92449855648 12803.35022367306 11949.069594031274 15497.016290565942 13049.56388608086 0.9090926462410787 1.21295107702594 1.162576587738348 0.9124809028344317 0.7189172163933151 1.0731335254424539 0.9811324221593014 0.915668117213985 1.1875505132470845 1.0 13.67171397255903 -5.763280262757148 24.999954738542105 0.9606458025031767 1.1066812083901194 0.14857812341225596 0.13503410692899503 81.2078724999824 1102863.4484398859 0.03797742379104353 0.05973642270298114 1.7247245182984391e-06 5.763280262757148 0.14603540588694275 EESS(ph)EDENEVSNILR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EESSEDENEVSNILR 15 0 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 EES(0.057)S(0.943)EDENEVSNILR;EES(0.003)S(0.997)EDENEVSNILR 225.6 6.1029999999999986e-92 5008700.0 42311.0 50163.0 53048.0 49107.0 59406.0 36355.4 50501.0 43486.0 45729.0 38710.0 True False 49473.41661965766 55142.85112428234 54312.86550566033 46355.693997042086 47765.82074953922 34448.85882397606 45717.17968442211 42344.53857722558 46397.700114231506 45727.816571808595 1.081910756485982 1.2058929390973405 1.1877423760299208 1.0137307545451575 1.0445681497722563 0.7533458058265116 0.9997673869389809 0.926012693187087 1.014649366461024 1.0 15.480784414018471 -6.027942124916348 2.060146634423005 0.9419051718509318 1.1629360448374324 0.5394928283855862 0.08251961827012198 0.23210181213065292 1.968585622634416 0.026196986871618647 0.040464518454134846 9.376869569252623e-07 6.027942124916348 0.2210308729865006 EESS(ph)EDENEVSNILR ddPTM_PC-9_Lapatinib_30min_R1 2 EESSEDENEVSNILR 15 0 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 EES(0.021)S(0.979)EDENEVSNILR;EES(0.049)S(0.951)EDENEVSNILR 298.7 2.1024999999999995e-104 4477500.0 25142.0 25349.0 31042.0 26514.0 28082.0 24310.0 24460.0 23935.0 25949.0 23819.0 True False 24783.47046952189 25290.30594793793 28489.846585585197 28463.92800811118 26430.271971336228 23270.317969377844 25726.41911630082 25047.107479013386 23026.350364916074 27936.082413177504 0.8871491035490172 0.9052917862244151 1.0198225421953395 1.0188947608017038 0.946098009750609 0.8329842969822135 0.920902893104497 0.8965862538835659 0.8242512326658408 1.0 14.769842099675657 -6.547270838426174 23.02364117954986 0.8900413272339929 0.9614738554283355 0.20131637596579766 0.06004360629264317 139.24227665326708 131428.32032938805 0.02015570260071991 0.020157213821084895 2.836149772926697e-07 6.547270838426174 0.07143252819434265 EESTSSGNVSNR ddPTM_PC-9_Lapatinib_30min_R1 2 EESTSSGNVSNR 12 0 A0A1W2PRL9;A0A1W2PPZ5;P23193-2;P23193 A0A1W2PRL9 TCEA1 Transcription elongation factor A protein 1 0 ; 126.66 0.0011845999999999998 1773100.0 9360.9 9686.9 10242.5 8731.3 10476.7 8699.4 10413.1 12054.8 10675.3 9430.5 False True 9227.411849421183 9664.470578211358 9400.401187193369 9373.428928762956 9860.481103984705 8327.346941291877 10952.239366310392 12614.910016211006 9472.935298107384 11060.549359648627 0.8342634302672938 0.8737785316043633 0.8499036423532585 0.8474650421035446 0.8915001220425777 0.7528872816816778 0.9902075394434409 1.140531957863959 0.8564615544926534 1.0 13.433135423237609 -7.383507851764565 6.973759730150168 1.0113557383510285 0.8463390926074932 0.5208146602987667 0.0725175713655645 0.18922791794215235 10.004391225575 0.028849680686373013 0.019328017312451293 4.135158381799564e-08 7.383507851764565 -0.16501664574353536 EESYS(ph)PSKDR ddPTM_PC-9_AZD4547_30min_R2 3 EESYSPSKDR 10 1 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 EES(0.003)YS(0.943)PS(0.054)KDR;EESYS(0.924)PS(0.076)KDR;EES(0.197)Y(0.001)S(0.769)PS(0.033)KDR 117.95 0.0044122 61192000.0 71728.0 71195.0 70921.0 80590.0 82340.0 79908.0 74652.0 85275.0 79618.0 80801.0 True False 94536.01196491711 94207.39145589361 69980.5412010418 62011.22060308818 70908.5122918578 74911.34012790555 81295.8833799133 72097.7081745573 83826.4449366316 77972.1815839103 1.2124325630568837 1.2082179764909065 0.8975065180872458 0.7952992893542985 0.9094078279129476 0.9607444425200442 1.0426267641675022 0.9246593683795913 1.0750814358890446 1.0 16.25067187981444 -5.254823114371306 24.588839637811926 0.9445969495966207 1.2103253217376369 0.6571895868343842 0.07491211779867873 253.45768742545056 941947.04089164 0.02066447527664606 0.05199940162289531 5.561307199720452e-06 5.254823114371306 0.2657283721410162 EESYS(ph)PSKDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EESYSPSKDR 10 1 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 EESYS(0.946)PS(0.053)KDR 115.92 0.0052307 19856000.0 21234.0 20428.0 20353.0 25406.0 29153.0 22106.0 27493.0 28253.0 18328.0 20244.0 True False 24828.496809383156 22455.956836051246 20838.29270918234 23982.58418736334 23440.67892656157 20946.722444611096 24888.664007917017 27511.388686527953 18596.012326830565 23914.076948584185 1.038237723444856 0.9390267031561398 0.8713818540429199 1.002864724359901 0.9802042109741291 0.8759159924778628 1.0407536975576444 1.150426535202595 0.7776178176064424 1.0 14.54557248584752 -7.292905334079951 24.985683659463476 1.0047350494653948 0.9507441072347735 0.03363283244810589 0.09869271399788389 2126.494491598686 1688544.0159515373 0.040208833369923536 0.027111763315657164 5.094419052354154e-08 7.292905334079951 -0.053990942230621286 EESYS(ph)PSKDR ddPTM_PC-9_Lapatinib_30min_R1 3 EESYSPSKDR 10 1 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 EES(0.001)YS(0.797)PS(0.203)KDR;EESYS(0.951)PS(0.049)KDR;EES(0.005)YS(0.985)PS(0.009)KDR 129.74 0.0011401 72755000.0 92793.0 97882.0 95555.0 99611.0 103153.0 90416.0 95578.0 90923.0 95508.0 79647.0 True False 91469.75480384786 97655.36024285226 87698.83675296664 106936.72523255482 97085.74334660103 86549.11844999042 100526.56117325436 95147.61451073046 84750.88329617328 93413.8778270434 0.9791880706762318 1.0454052707635368 0.9388202137945906 1.144762723912919 1.0393074948280825 0.9265124247409668 1.0761416131271218 1.018559733564397 0.9072622319896652 1.0 16.511349276218404 -8.160035950793217 8.566751700447487 0.953938174067021 1.0227640189799152 0.1504722766783464 0.06405955844641784 0.5468380557529741 41.15267559602198 0.04249794073603091 0.015976741111443486 6.91773703687144e-09 8.160035950793217 0.06882584491289423 EESYSPS(ph)KDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EESYSPSKDR 10 1 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 EES(0.001)YS(0.351)PS(0.648)KDR 94.76700000000001 0.029805 35000000.0 27799.0 39124.0 29517.0 31949.0 42006.0 32123.0 36537.0 31017.0 26903.0 25110.0 True False 32504.82164472272 43007.97215849172 30220.797223845853 30159.00111005556 33775.22584259408 30438.413330690422 33075.95085502725 30202.836615228018 27296.405479524386 29662.244229349377 1.095831501938776 1.4499230680575876 1.0188304360984195 1.016747110463566 1.1386604999083347 1.0261669041404853 1.1150859186271609 1.0182249320617403 0.9202407366235591 1.0 14.85634013499766 -5.289731127523472 24.975780358638822 1.0384555144326717 1.2728773162769065 0.49255291270659485 0.09771076726633529 482.04033207973436 425541.3551551644 0.024131956285722154 0.05024955938720152 5.131789956818006e-06 5.289731127523472 0.23442180184423478 EETGDEEDGS(ph)PIALHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EETGDEEDGSPIALHR 16 0 P79522-2 P79522-2 PRR3 Proline-rich protein 3 1 EETGDEEDGS(1)PIALHR 90.71799999999999 0.0072786000000000005 0.0 11979.0 22314.0 17803.0 14886.0 17653.0 15702.0 20133.0 14928.0 11691.0 10705.0 True False 14006.808103965379 24529.186451911482 18227.491038253473 14051.985681063163 14194.021373120826 14878.559478208792 18225.8564897026 14536.155817523428 11861.958757800961 12645.731759266624 1.107631283867885 1.9397206044590358 1.441394723946806 1.1112038392531973 1.1224357469641593 1.1765676958398221 1.44126546701 1.1494910768506161 0.9380207475228688 1.0 13.62636290211167 -5.9012799715582975 0.35528701447431393 1.0209073354843232 1.674782612233361 0.2671072508258019 0.23902252782665323 4.047179422389018 0.7299473281746003 0.26094000316558363 1.0636051618239084 1.2552205144448983e-06 5.9012799715582975 0.6538752767490377 EEVHGEAQR ddPTM_PC-9_AZD4547_30min_R2 1 EEVHGEAQR 9 0 J3KN16;R4GMY1;Q5VYK3 J3KN16 KIAA0368;ECM29 Proteasome-associated protein ECM29 homolog 0 87.29799999999999 0.0092309 1801100.0 12739.0 11355.0 16193.0 16884.0 15498.0 13381.0 13073.0 14765.0 16836.0 23009.0 False True 16789.73701233934 15025.281690872549 15978.270239681748 12991.654655199665 13346.370214952758 12544.283954691677 14236.471674243257 12483.4085159465 17725.91658862478 22203.46191339454 0.7561765402993622 0.6767089632003892 0.7196296821642322 0.5851184245895579 0.6010941116755031 0.5649697332614679 0.6411825205354535 0.5622280239288141 0.7983402163935246 1.0 14.43849701539968 -8.544734400903788 3.9845171456511133 0.9996107628814359 0.6378503621610861 0.7732910863316383 0.061441259135314945 0.09357724725383432 4.697666813483368 0.06303117302257846 0.016521285294698845 2.8527623823862174e-09 8.544734400903788 -0.36176040072034976 EEVHGEAQR ddPTM_PC-9_Lapatinib_30min_R1 1 EEVHGEAQR 9 0 J3KN16;R4GMY1;Q5VYK3 J3KN16 KIAA0368;ECM29 Proteasome-associated protein ECM29 homolog 0 96.665 0.0042232 1422100.0 19772.0 23896.0 22177.0 21941.0 26539.0 19033.0 24498.0 25396.0 28328.0 19226.0 False True 19490.047654259277 23840.670280165876 20353.692665695602 23554.614333030353 24978.028197681513 18219.00295809001 25766.386570365383 26575.990872656108 25137.40233293546 22549.188482965325 0.864334770583116 1.0572739811978686 0.9026352625094114 1.0445881168107036 1.1077129545726687 0.807967123599746 1.1426746727417918 1.1785785946457812 1.1147807980728615 1.0 14.46078789317784 -7.36372669479979 24.831335745176833 1.1238921110179314 0.9756477283262217 0.3426262716539138 0.0966805646538242 39.467178465818904 9571.24261204916 0.038914111615228036 0.026235884792513563 4.327861013185413e-08 7.36372669479979 -0.1482443826917097 EEVVT(ph)VETWQEGSLK ddPTM_PC-9_AZD4547_30min_R2 1 EEVVTVETWQEGSLK 15 0 P09211;A8MX94;A0A087X2E9 P09211 GSTP1 Glutathione S-transferase P 1 EEVVT(0.714)VET(0.271)WQEGS(0.015)LK 83.86200000000001 0.022899 0.0 5586.6 7270.1 7569.6 7044.7 6536.8 7993.0 7106.3 9460.2 7723.0 7962.2 True False 7363.0225915013 9620.017650445836 7469.222158111227 5420.65325453003 5629.27815338129 7493.196446442761 7738.746933272766 7998.343463769528 8131.22201318301 7683.445801505062 0.9582969388628997 1.2520447074099788 0.9721188059461717 0.705497688741191 0.7326502065360578 0.9752390581026765 1.0071974389090987 1.0409839114375978 1.0582780464970853 1.0 12.907537747411679 -9.566455111023888 14.162276275556707 1.0000025298746842 0.9644897713062072 0.004211996017275177 0.14839068816063292 0.0 0.0 0.16069785757766553 0.038974955329598736 2.713594116608718e-10 9.566455111023888 -0.03551275856847702 EEVVTVETWQEGS(ph)LK ddPTM_PC-9_Lapatinib_30min_R1 2 EEVVTVETWQEGSLK 15 0 P09211;A8MX94;A0A087X2E9 P09211 GSTP1 Glutathione S-transferase P 1 EEVVTVETWQEGS(1)LK;EEVVTVET(0.001)WQEGS(0.999)LK 136.01 3.4318e-06 0.0 15363.0 16242.9 15925.099999999999 13633.2 15241.0 15646.4 17481.699999999997 15049.1 14822.5 13644.599999999999 True False 15143.920802770841 16205.290563010796 14615.79975066371 14635.831007021998 14344.554344958886 14977.23994553984 18386.816887384957 15748.33612544059 13153.033962155321 16003.050929713336 0.9463146039642152 1.0126375673104906 0.9133133309927873 0.9145650458343052 0.8963637251397438 0.9358990364600515 1.1489569687768482 0.9840833597673673 0.8219078986828503 1.0 13.966059356010161 EEYARS(ph)TR ddPTM_PC-9_Lapatinib_30min_R1 1 EEYARSTR 8 1 Q8TF61 Q8TF61 FBXO41 F-box only protein 41 1 EEYARS(0.997)T(0.003)R 56.632 0.039989 666510.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 EEYEERLARLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EEYEERLARLK 11 2 A0A0A0MRS8;Q9P2E2-3;Q9P2E2 A0A0A0MRS8 KIF17 Kinesin-like protein;Kinesin-like protein KIF17 0 110.87 0.016992 4087200.0 13957.0 13238.0 13543.0 14190.0 19279.0 14033.0 15689.0 12586.0 15990.0 10705.0 False True 16319.644436684588 14552.181153105854 13865.916482113515 13394.980304600713 15501.41834545949 13297.084776315374 14202.824341476373 12255.630835969305 16223.823499892007 12645.731759266624 1.2905259060809802 1.1507583293819441 1.0964898470151998 1.0592491252856957 1.2258221699270393 1.0515077363215022 1.1231318686693423 0.9691515737702202 1.2829485717980222 1.0 13.62636290211167 -4.768276197413302 2.491147998961729 1.1021638373157467 1.3362150748218924 0.28678134836933666 0.09002370817540128 0.6882221031116119 5.236837396432687 0.021771169538557615 0.35358253820169766 1.7049977200628154e-05 4.768276197413302 0.23405123750614565 EFAGEDTSDLFLEER ddPTM_PC-9_Lapatinib_30min_R1 1 EFAGEDTSDLFLEER 15 0 O14980 O14980 XPO1 Exportin-1 0 117.23 0.00060734 1536300.0 5304.1 4010.2 5509.9 6465.7 4496.0 4552.7 6223.2 5542.2 6147.5 5071.8 False True 5228.462561347189 4000.914628285954 5056.897290829065 6941.209146942908 4231.554119476097 4357.99163386205 6545.406845648538 5799.710844795825 5455.103813955126 5948.453872251297 0.87896160475199 0.6725974033268812 0.8501196108149686 1.1668929937109667 0.7113704183226004 0.7326259440611063 1.1003543082315799 0.9749946741372011 0.9170624722169267 1.0 12.538299015150036 -3.660646059265799 0.185333728523979 1.0232638613653 0.464789509902236 0.12918756567303102 0.14622095429863827 54.8395191291804 1.2605196117652477 0.3731008150013619 7.518662035735527 0.00021845095152090327 3.660646059265799 -0.558474351463064 EFALHK ddPTM_PC-9_Lapatinib_30min_R1 1 EFALHK 6 0 A0A087WW66;Q99460-2;Q99460;F8WCE3;C9J9M4 A0A087WW66 PSMD1 26S proteasome non-ATPase regulatory subunit 1 0 95.95700000000001 0.02053 0.0 22637.0 34851.0 33199.0 36704.0 37670.0 34283.0 37882.0 36076.0 39149.0 34350.0 False True 22314.19222888261 34770.30465073907 30469.50637184601 39403.33460095465 35454.32466206952 32816.796007576304 39843.344601950455 37752.222661912965 34739.62736275384 40287.351731502065 0.5538758759224766 0.8630575889541772 0.7563045239337699 0.9780572042451683 0.8800361189873537 0.8145682105462326 0.9889789943873519 0.9370738219160036 0.8622961269402508 1.0 15.298039353330818 -4.286760190946151 1.0629917388099621 0.9119427726731462 9.51570246847097e-31 0.6654336609143234 0.07383398717358026 2.6942341119002693 1.2100566771009231 0.022315412175193707 3.576719579025105 5.167016031945828e-05 4.286760190946151 -0.9119427726731462 EFAPS(ph)DEELDSYR ddPTM_PC-9_AZD4547_30min_R2 2 EFAPSDEELDSYR 13 0 I3L0X5;I3L4C3;O75391 I3L0X5 SPAG7 Sperm-associated antigen 7 1 EFAPS(1)DEELDSYR;EFAPS(1)DEELDSYR 158.31 0.00010689 6035900.0 16084.1 16793.8 21953.1 26238.0 22239.4 22546.9 20395.0 21919.0 19020.7 22842.0 True False 21198.509229937004 22222.067429341732 21661.987550099264 20189.234473059023 19151.843189987132 21137.038778718914 22210.115489649754 18531.922198512115 20026.095370471343 22042.30853256369 0.9617191048124512 1.0081551756029765 0.9827458643044322 0.9159310352285891 0.8688673947964027 0.9589303564775261 1.007612948382342 0.8407432538717264 0.9085298547965727 1.0 14.427987707545183 -5.747450266547291 12.219275350437766 0.9240819887976616 0.9866288735272347 0.19939884420476384 0.05035534780974174 0.9112962298992505 784.0707390362237 0.014032357234534448 0.02363172197685002 1.7887503570332917e-06 5.747450266547291 0.06254688472957315 EFAPS(ph)DEELDSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EFAPSDEELDSYR 13 0 I3L0X5;I3L4C3;O75391 I3L0X5 SPAG7 Sperm-associated antigen 7 1 EFAPS(1)DEELDSYR;EFAPS(0.999)DEELDS(0.001)YR 154.72 0.00017216 5031900.0 15237.099999999999 15362.6 17325.8 17673.9 20091.9 20498.0 14949.7 15788.6 17572.5 13403.0 True False 17816.44008355712 16887.69740011362 17738.912780462397 16683.68868255691 16155.036425910972 19423.048795333314 13533.556189544872 15374.165979404488 17829.464568596137 15832.857801910373 1.1252826436303502 1.0666234492471707 1.1203860353196655 1.0537383011514116 1.0203487347661093 1.2267557151299466 0.854776589221431 0.9710291200587591 1.126105267391769 1.0 13.950634062347998 -7.261594724883575 24.999983178354338 0.9855635121584222 1.0954773211457607 0.3255869175401668 0.08014904609674427 18.26016510294119 2938205.4653475783 0.03187279009138075 0.023041164837383922 5.475266657437043e-08 7.261594724883575 0.10991380898733849 EFAPS(ph)DEELDSYR ddPTM_PC-9_Lapatinib_30min_R1 2 EFAPSDEELDSYR 13 0 I3L0X5;I3L4C3;O75391 I3L0X5 SPAG7 Sperm-associated antigen 7 1 EFAPS(1)DEELDSYR;EFAPS(1)DEELDSYR 120.53 0.00021122 5950100.0 11205.2 12026.400000000001 16135.800000000001 12615.2 15204.4 14370.1 12867.0 13300.8 14585.7 12518.1 True False 11045.411793217985 11998.553609699811 14809.176809989238 13542.963891073547 14310.107085000518 13755.524321339228 13533.190301285473 13918.803724957646 12942.904871769864 14681.836905680228 0.7523181100686827 0.8172379033210561 1.0086732951147104 0.9224298007175067 0.9746809732959306 0.9369075824577087 0.9217641081443728 0.9480287660444333 0.881558959884809 1.0 13.841744860600217 -5.083905517816868 4.561742229395205 0.9455248475003267 0.7647389838454202 0.7691758333708605 0.03670144404244637 0.08730219029876636 3.153248064102308 0.009017296429748628 0.027484868078659436 8.243174284563205e-06 5.083905517816868 -0.18078586365490656 EFAPS(ph)DEELDSYRR ddPTM_PC-9_AZD4547_30min_R2 2 EFAPSDEELDSYRR 14 1 I3L0X5;I3L4C3;O75391 I3L0X5 SPAG7 Sperm-associated antigen 7 1 EFAPS(0.999)DEELDS(0.001)YRR;EFAPS(0.999)DEELDS(0.001)YRR 83.823 0.0034902 3500600.0 11933.4 10972.3 12723.3 22199.6 19258.7 16808.9 13574.7 18738.9 16058.7 13615.900000000001 True False 15727.972969860297 14518.88139997894 12554.580728743467 17081.82520040098 16584.96193435997 15757.836825799042 14782.822002321582 15843.233582083976 16907.530097514176 13139.21148535742 1.1970256348630846 1.105004011554198 0.9555048826738594 1.3000647123640017 1.2622494091706002 1.1992985152388989 1.1250920208412682 1.2057978973654522 1.2867994488372638 1.0 13.681591078322445 -5.772951141576718 24.999563369954362 1.2054309753857209 1.087760727180239 0.20754057552882166 0.09860350182645092 312.8324330493566 679363.6213320572 0.02738582284798808 0.041006349798941424 1.686742774419336e-06 5.772951141576718 -0.11767024820548189 EFAPS(ph)DEELDSYRR ddPTM_PC-9_Lapatinib_30min_R1 1 EFAPSDEELDSYRR 14 1 I3L0X5;I3L4C3;O75391 I3L0X5 SPAG7 Sperm-associated antigen 7 1 EFAPS(0.594)DEELDS(0.358)Y(0.048)RR 70.197 0.012815 1749500.0 8430.9 5766.6 8982.6 7715.0 8401.3 8641.4 6020.3 5210.6 9734.0 6444.2 True False 8310.673819962292 5753.247791998846 8244.08530183873 8282.386836485543 7907.152051591306 8271.827466087268 6332.001676445862 5452.703498230506 8637.654416435818 7558.071383643247 1.0995759894445805 0.7612058023756829 1.0907657368360024 1.0958333701914775 1.046186474065794 1.0944362716643155 0.837780083706172 0.7214411218754747 1.1428384276879078 1.0 12.883802429132121 -7.26272540502118 24.985290272362285 0.9023016704688958 1.025363740856749 0.11214311034580471 0.13928795453693651 233.37618703853565 4534028.130990849 0.056037614881053556 0.040147665231615975 5.461030410599393e-08 7.26272540502118 0.12306207038785333 EFCGPADPTPKSPIS(ph)HK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EFCGPADPTPKSPISHK 17 1 B4DXC8 B4DXC8 NME7 1 EFCGPADPTPKS(0.022)PIS(0.978)HK 52.372 0.032242 11324000.0 3993.2 9229.5 4802.6 6046.2 10296.0 7916.1 7738.0 10250.0 7885.9 5365.0 True False 4669.169890704946 10145.743764359459 4917.112197961927 5707.451016044876 8278.57271045442 7500.965780502394 7005.0006217314185 9980.948360772714 8001.216368842931 6337.632030683365 0.7367372968483128 1.6008729625259543 0.7758595283152993 0.9005652250576406 1.3062564488398942 1.1835596866758438 1.105302514853658 1.5748702847452163 1.2624930463153108 1.0 12.629728182482681 -6.274545660982913 24.651673629840822 1.2580589305085002 1.0299169628502909 0.15598433503822318 0.2629473933540721 1276.5271033272622 2401020.9754666835 0.08040134834467323 0.091711301403841 5.314401218590464e-07 6.274545660982913 -0.22814196765820927 EFDELNPS(ph)AQR ddPTM_PC-9_AZD4547_30min_R2 2 EFDELNPSAQR 11 0 H7C5W9;P16615-5;P16615-2;P16615-3;P16615-4;P16615 H7C5W9 ATP2A2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 1 EFDELNPS(1)AQR;EFDELNPS(1)AQR 130.15 0.00022343 7349400.0 28944.0 31005.0 45701.0 39734.0 39014.0 27506.0 31908.0 34961.0 30027.0 23185.0 True False 38147.589927400106 41026.75991417905 45094.97487949709 30573.94018418049 33597.57953065992 25786.045471769612 34747.75018601346 29558.58077385746 31614.165918664545 22373.300206964777 1.7050497501269308 1.8337375145669157 2.015570991420349 1.3665368944838485 1.5016818806284573 1.1525365159916128 1.5530900611254719 1.3211542553143731 1.4130309621833572 1.0 14.449490458523654 -1.5228795338833225 0.12454241028195889 0.8794434403178274 4.181331793151245 0.6022469044914718 0.18368397479046553 62.167828204682046 0.5305014637607657 1.1689413631507586 35.78471712249234 0.029999945525285135 1.5228795338833225 3.301888352833418 EFDELNPS(ph)AQR ddPTM_PC-9_Lapatinib_30min_R1 2 EFDELNPSAQR 11 0 H7C5W9;P16615-5;P16615-2;P16615-3;P16615-4;P16615 H7C5W9 ATP2A2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 1 EFDELNPS(1)AQR;EFDELNPS(1)AQR 106.32 0.0024481999999999998 5611100.0 44276.0 45635.0 21708.0 19265.7 21781.0 24561.0 26790.0 17899.1 31605.0 10942.3 True False 43644.616120776 45529.33496130605 19923.252035303245 20682.563846491183 20499.884403093616 23510.583284487417 28177.055115523253 18730.757529877104 28045.31208459564 12833.661975301751 3.400792089176855 3.5476495367360292 1.5524214424258125 1.6115870814031539 1.5973526841010328 1.831946589347085 2.1955584594443662 1.4595021721722337 2.185293031604584 1.0 13.647645269368349 -5.259694306383778 24.9996068032374 1.714176094814696 3.4742209916751556 0.8234025406196768 0.3322012809120316 53.91554999282147 772368.8909609593 0.08123998859485462 0.19339053507776066 5.499278239137182e-06 5.259694306383778 1.7600448968604596 EFDRHS(ph)GSDR ddPTM_PC-9_Lapatinib_30min_R1 1 EFDRHSGSDR 10 1 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 EFDRHS(0.997)GS(0.003)DR 130.1 0.0010827999999999999 5820500.0 40543.0 31301.0 46528.0 35386.0 43862.0 44160.0 33394.0 34801.0 44991.0 39893.0 True False 39964.84938532437 31228.524457627722 42702.6474432739 37988.40448423556 41282.12339600988 42271.37974198788 35122.97792190308 36417.98150729662 39923.63980376654 46788.45189591885 0.8541605410289356 0.6674408575666434 0.9126749382148004 0.8119183889379575 0.8823143686788821 0.9034575419597294 0.750676213866497 0.7783540602777071 0.8532797770821074 1.0 15.51386487413719 -12.651569979999284 1.0719516653181935 3.8856911771816827 0.8220344210067301 0.35156709013210696 0.07175331166772886 67383.26563996733 1341.3422241753133 469904.0953401589 0.021579663842309013 2.2306427441191316e-13 12.651569979999284 -3.063656756174953 EFEDRDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EFEDRDR 7 1 Q13951-2;J3KS23;A0A494C0A9;Q13951 Q13951-2 CBFB Core-binding factor subunit beta 0 83.37700000000001 0.027360000000000002 8074000.0 15349.0 10915.0 17246.0 17293.0 19765.0 15784.0 13723.0 18295.0 20171.0 11082.0 False True 17947.282543431385 11998.569065278021 17657.21004581922 16324.129274662446 15892.190134239678 14956.259253856035 12423.058094083768 17814.775635154805 20465.96271521712 13091.078874936275 1.3709551913091464 0.9165454719129426 1.3487971629003859 1.2469659247043463 1.2139710016312188 1.1424772088487505 0.9489712966185334 1.3608332670932384 1.5633518757877582 1.0 13.676296378542393 EFGSLPT(ph)TPSEQR ddPTM_PC-9_AZD4547_30min_R2 1 EFGSLPTTPSEQR 13 0 O15400-2;O15400 O15400-2 STX7 Syntaxin-7 1 EFGSLPT(0.603)T(0.397)PSEQR 122.34 0.00044817 3418600.0 23309.0 21157.0 31198.0 42950.0 31904.0 21479.0 32675.0 31761.0 26783.0 30142.0 True False 30720.77714268135 27995.58650231532 30784.294135588927 33048.54107088517 27474.6803031264 20135.914734535738 35583.01170013758 26853.067245172842 28198.694701421806 29086.737754510752 1.0561781593371429 0.9624862966275337 1.0583618690898027 1.1362065196108155 0.9445775781048407 0.6922713335706777 1.2233414417407256 0.9232065648547502 0.9694691422398777 1.0 14.828073878486602 -6.305893888029311 24.744301741374688 0.9548708482265758 1.0471819961545257 0.11713482807059306 0.1263716541912736 948.303402589792 527843.2295105386 0.0396121552921987 0.04491621087936102 4.9443147758335e-07 6.305893888029311 0.09231114792794992 EFGSLPTT(ph)PSEQR ddPTM_PC-9_AZD4547_30min_R2 1 EFGSLPTTPSEQR 13 0 O15400-2;O15400 O15400-2 STX7 Syntaxin-7 1 EFGSLPT(0.007)T(0.991)PS(0.002)EQR 124.48 0.00037445 4669800.0 16941.0 21695.0 23513.0 25987.0 24110.0 16403.0 19101.0 25072.0 19137.0 24918.0 True False 22327.885605309762 28707.484481151896 23201.202256878732 19996.09864514769 20762.742668893476 15377.31781696491 20800.951996459924 21197.6984972442 20148.542751040175 24045.628404448908 0.9285631978400977 1.1938754104609075 0.9648823422966172 0.831589772112091 0.8634726578845394 0.6395057578998355 0.8650616921540443 0.8815614273288119 0.8379295567635198 1.0 14.553487009407716 -5.596142228190503 3.811377432246073 0.833953884594165 1.0659890429877792 0.41562763422525195 0.10275115412440652 0.1845688629364759 5.281775615698058 0.02771760822712897 0.05195701071676646 2.534298530789486e-06 5.596142228190503 0.23203515839361422 EFGSLPTT(ph)PSEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EFGSLPTTPSEQR 13 0 O15400-2;O15400 O15400-2 STX7 Syntaxin-7 1 EFGSLPT(0.045)T(0.952)PS(0.003)EQR;EFGSLPT(0.006)T(0.941)PS(0.053)EQR 128.35 0.00025902 5510900.0 41290.0 40165.0 43504.0 41824.0 55778.0 39407.0 43990.0 35849.0 37857.0 34705.0 True False 48279.58148532686 44152.31575876243 44541.300349838755 39480.73687523749 44848.70130572326 37340.42754794123 39822.94873997997 34908.00173515521 38410.587006592374 40996.741775371185 1.177644354028418 1.0769713359339925 1.0864595190000432 0.9630213320746276 1.093957699161989 0.9108145167373646 0.9713686262722377 0.8514823428267222 0.9369180413665837 1.0 15.323221635346007 -5.359828889764404 0.5172945258275001 0.9219778496258971 1.235137634344927 0.6183050175204474 0.058445511340617116 1.6159799878008716 0.5068186775204393 0.0382231248476073 0.28647157449193283 4.36687851563865e-06 5.359828889764404 0.31315978471902983 EFGSLPTT(ph)PSEQR ddPTM_PC-9_Lapatinib_30min_R1 1 EFGSLPTTPSEQR 13 0 O15400-2;O15400 O15400-2 STX7 Syntaxin-7 1 EFGSLPT(0.014)T(0.984)PS(0.002)EQR 182.1 0.00018039 5324600.0 38199.0 33719.0 29492.0 21198.0 27216.0 24988.0 17732.0 20893.0 30760.0 15807.0 True False 37654.275255161345 33640.92572718918 27067.28160241217 22756.971634455018 25615.208388714713 23919.32148987304 18650.076196657647 21863.765053646403 27295.484882840105 18539.218888496456 2.03106050376943 1.814581613687257 1.4600011880331893 1.227504339385931 1.3816767870737474 1.290201147833414 1.0059796105126078 1.1793250398059014 1.472310405686881 1.0 14.178292839832627 -5.093290680074782 1.064893068007484 1.2096583894917063 2.2457504722432526 0.8071046337587491 0.137711910830302 0.4793129998264195 0.6314472306822022 0.04640974015188708 0.499683224893874 8.066949160181623e-06 5.093290680074782 1.0360920827515463 EFHLNES(ph)GDPSSK ddPTM_PC-9_AZD4547_30min_R2 2 EFHLNESGDPSSK 13 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;A0A087X027;P0DME0;Q01105-2 Q01105;Q01105-2 SET;SETSIP Protein SET;Protein SETSIP 1 EFHLNES(0.974)GDPS(0.021)S(0.004)K;EFHLNES(0.954)GDPS(0.044)S(0.002)K 105.02 0.00072256 7525700.0 58056.0 59582.0 73304.0 96175.0 89674.0 75448.0 67604.0 73972.0 68151.0 84975.0 True False 76516.60036018313 78840.71631048601 72331.94106401734 74003.3396389379 77224.31298591258 70730.22463295558 73620.62503369844 62541.32710745644 71753.3227269759 82000.05111437722 0.9331286910230637 0.9614715507983717 0.8820962923928624 0.9024791891375147 0.9417593274203788 0.8625631773606824 0.8978119407634174 0.7626986356413497 0.8750399756079573 1.0 16.323337188578165 -6.7713319553387175 24.887776867312294 0.8659282225495506 0.922714009832068 0.10627749156433874 0.058116343660683925 336.4454612179964 846425.2886851033 0.019829078323219625 0.01769699454423556 1.6930432189988128e-07 6.7713319553387175 0.056785787282517375 EFHLNES(ph)GDPSSK ddPTM_PC-9_Lapatinib_30min_R1 1 EFHLNESGDPSSK 13 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;A0A087X027;P0DME0;Q01105-2 Q01105;Q01105-2 SET;SETSIP Protein SET;Protein SETSIP 1 EFHLNES(1)GDPSSK 125.98 7.6486e-05 7423400.0 73074.0 78682.0 84796.0 64353.0 86378.0 78993.0 70127.0 72425.0 76163.0 60137.0 True False 72031.95135986945 78499.81666320763 77824.40020202576 69085.73429531492 81297.41586568201 75614.65353167687 73757.83292595376 75790.12990046148 67584.72090805431 70531.60032248445 1.021272040199359 1.1129737068816095 1.1033976238479943 0.9795004505702587 1.1526381862026966 1.0720677424863707 1.0457416617334405 1.0745556538336576 0.9582190195464668 1.0 16.105982153574875 -8.254423476105321 24.489713087730117 0.9791095074916628 1.071758689167228 0.37789132559573035 0.04675393883763606 373.5526827855204 1303938.3099821939 0.032025789446199736 0.011502568318113443 5.5664270760967704e-09 8.254423476105321 0.09264918167556513 EFHLNESGDPS(ph)SK ddPTM_PC-9_Lapatinib_30min_R1 1 EFHLNESGDPSSK 13 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;A0A087X027;P0DME0;Q01105-2 Q01105;Q01105-2 SET;SETSIP Protein SET;Protein SETSIP 1 EFHLNES(0.31)GDPS(0.545)S(0.145)K 99.74700000000001 0.0013765000000000001 6089300.0 73336.0 68099.0 68442.0 50088.0 70447.0 65802.0 66641.0 63922.0 76186.0 61965.0 True False 72290.21519182483 67941.32094949017 62814.96295376012 53771.63860866986 66303.44596413086 62987.8018519539 70091.34490308273 66892.04947873393 67605.13040585363 72675.56768682752 0.9946976335064455 0.9348577948817944 0.8643202241562313 0.7398860486426719 0.9123209914210054 0.8666984497923704 0.9644416567218205 0.9204200477247616 0.9302318861433139 1.0 16.149182815202632 -7.260033305457475 24.86410987273635 0.9471417359698135 0.8813512939495679 0.2092198820513601 0.06424944794010089 218.51809042493443 3864195.3877693005 0.02742472836551439 0.020058805605913672 5.4949873192586925e-08 7.260033305457475 -0.06579044202024564 EFHLNESGDPSSK ddPTM_PC-9_AZD4547_30min_R2 2 EFHLNESGDPSSK 13 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;A0A087X027;P0DME0;Q01105-2 Q01105;Q01105-2 SET;SETSIP Protein SET;Protein SETSIP 0 ; 94.71700000000001 0.0031034 32706000.0 119803.0 122879.0 235110.0 356820.0 289450.0 245600.0 214810.0 283560.0 224510.0 245060.0 False True 157897.86194279717 162597.23372018736 231992.28778185495 274560.66181404545 249264.86377068554 230242.59317482068 233927.67385788992 239742.31756056764 236377.14025375116 236480.52399045887 0.667699222237717 0.6875713525006718 0.9810206940814077 1.161028642786342 1.054060856955571 0.9736217989102144 0.9892048186908113 1.0137930748590542 0.9995628234623166 1.0 17.8513618457419 -5.282600662471424 4.275255034437062 1.0279168650076682 0.6703743709408787 0.8842350289786536 0.049997317714849866 0.06205880892597849 2.7926468982119728 0.014406590753461398 0.035272133040107526 5.216741745468647e-06 5.282600662471424 -0.3575424940667895 EFHLNESGDPSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EFHLNESGDPSSK 13 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;A0A087X027;P0DME0;Q01105-2 Q01105;Q01105-2 SET;SETSIP Protein SET;Protein SETSIP 0 ; 146.77 8.877e-05 28030000.0 220828.0 253209.0 350420.0 382720.0 466000.0 392360.0 381410.0 367920.0 362500.0 284038.0 False True 258209.8188481894 278345.91612001706 358775.3417752507 361277.43919498107 374690.64520898997 371783.95088969567 345280.0836307287 358262.4898434625 367800.87671737745 335531.84095642855 0.7695538465504976 0.829566324693943 1.0692736067985884 1.076730715526625 1.1167066712385323 1.1080437249410697 1.029053107587384 1.0677451320930988 1.0961727973982036 1.0 18.356090154752692 -5.214828761330529 3.5970379500697973 1.076074729507856 0.7818459981279817 0.9111977463503781 0.0339983456431198 0.058502013409169544 1.5591514295386326 0.008913502887615929 0.026367929251967227 6.097772799106354e-06 5.214828761330529 -0.2942287313798744 EFHLNESGDPSSK ddPTM_PC-9_Lapatinib_30min_R1 2 EFHLNESGDPSSK 13 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;A0A087X027;P0DME0;Q01105-2 Q01105;Q01105-2 SET;SETSIP Protein SET;Protein SETSIP 0 ; 139.86 5.417100000000001e-05 38482000.0 325560.0 289160.0 404630.0 359330.0 379040.0 355660.0 350450.0 326910.0 379600.0 250970.0 False True 320917.4546996082 288490.4677859373 371362.8833169693 385756.32688974036 356745.61242131225 340449.2508839542 368594.58623498015 342099.43204363 336845.4506347888 294349.8301034949 1.0902586714141196 0.9800938824544337 1.2616378381682647 1.3105369442683437 1.211978319457085 1.1566143957489308 1.252233052437572 1.1622205860399037 1.144371140001515 1.0 18.167172269375 -8.78915794016807 1.9503834452098605 1.0001603951445488 1.1816375351131028 0.2646597834808523 0.08878568526519542 1.6820809858389676 9.92959837330268 0.09360795318866748 0.02599826177308026 1.6249576988162103e-09 8.78915794016807 0.18147713996855397 EFITGDVEPTDAES(ph)EWHSENEEEEK ddPTM_PC-9_AZD4547_30min_R2 2 EFITGDVEPTDAESEWHSENEEEEK 25 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;A8MXH2;E9PKT8;C9JZI7 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 EFITGDVEPT(0.003)DAES(0.975)EWHS(0.021)ENEEEEK;EFITGDVEPT(0.003)DAES(0.988)EWHS(0.009)ENEEEEK 121.35 1.9181e-09 22669800.0 25546.3 28422.6 35744.6 32002.8 41145.0 43284.0 37146.1 53385.0 46828.0 37519.1 True False 33669.49200395044 37609.64961576345 35270.60324889325 24625.04889833118 35432.726964397436 40577.444637536406 40452.03093846915 45135.5749152593 49303.23247874323 36205.56772892525 0.9299534330199526 1.0387808277818125 0.97417622375011 0.6801453600369263 0.9786540907101872 1.120751508202933 1.1172875741470925 1.2466473458776814 1.3617583032499732 1.0 15.143923953025116 -6.85942054009093 2.2966608784543925 1.1997456982121923 0.912276348817005 0.5153868041649808 0.1225282483309351 0.25037161021143467 2.697790936950685 0.051162854941804614 0.04435527798182312 1.3822272794964153e-07 6.85942054009093 -0.2874693493951873 EFITGDVEPTDAES(ph)EWHSENEEEEK ddPTM_PC-9_Lapatinib_30min_R1 4 EFITGDVEPTDAESEWHSENEEEEK 25 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;A8MXH2;E9PKT8;C9JZI7 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 EFITGDVEPT(0.011)DAES(0.597)EWHS(0.391)ENEEEEK;EFIT(0.003)GDVEPT(0.128)DAES(0.869)EWHSENEEEEK;EFIT(0.003)GDVEPT(0.048)DAES(0.909)EWHS(0.039)ENEEEEK;EFITGDVEPT(0.001)DAES(0.995)EWHS(0.004)ENEEEEK 112.36 6.5447e-08 58614200.0 62046.3 67705.7 70884.4 70492.1 79148.7 68915.8 73727.6 85106.5 82527.7 80029.6 True False 61161.50838410215 67548.93161147585 65056.55825369674 75676.32418875194 74493.32907833131 65968.43188457619 77544.8543760827 89060.85868655315 73232.56137079197 93862.6097272611 0.6516067320290865 0.719657505877521 0.6931040852447337 0.8062456862071756 0.7936422106181409 0.7028190679575423 0.8261527630800667 0.9488427707831637 0.7802101559245543 1.0 16.51826295272445 -4.44322295317902 0.06476500276867907 1.341465002195131 5.769969148510946e-10 0.7023330473470749 0.05775295420313881 86.46516565421493 0.8014029851129906 4.808775359066062 13.427488679546771 3.603935807511752e-05 4.44322295317902 -1.3414650016181342 EFITGDVEPTDAES(ph)EWHSENEEEEKLAGDMK ddPTM_PC-9_AZD4547_30min_R2 1 EFITGDVEPTDAESEWHSENEEEEKLAGDMK 31 1 E9PNJ7;C9J6D1;Q99733;Q99733-2;A8MXH2;E9PKT8;C9JZI7 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 EFITGDVEPT(0.156)DAES(0.422)EWHS(0.422)ENEEEEKLAGDMK 43.306000000000004 0.015663999999999997 4051700.0 7750.6 5978.3 10099.0 12737.0 12207.0 11471.0 11338.0 13498.0 9586.4 10523.0 True False 10215.129577505088 7910.668562971671 9965.080661430626 9800.681434688342 10512.268758157723 10753.716556630161 12347.060035383616 11412.194253182917 10093.11753297651 10154.592972951925 1.0059614998567061 0.7790236973596837 0.9813372813636067 0.9651476391809822 1.0352230548441 1.0590002558718088 1.215908906272424 1.1238455626513812 0.9939460458790261 1.0 13.30984479272637 -6.16745983764014 1.3517195270913236 1.0943055736716152 0.9009152637632628 0.4224906450981928 0.08135307297299484 0.3705151986245167 1.3677100439218826 0.030643511525546743 0.047195871538869026 6.800489311512831e-07 6.16745983764014 -0.19339030990835238 EFITGDVEPTDAES(ph)EWHSENEEEEKLAGDMK ddPTM_PC-9_Lapatinib_30min_R1 2 EFITGDVEPTDAESEWHSENEEEEKLAGDMK 31 1 E9PNJ7;C9J6D1;Q99733;Q99733-2;A8MXH2;E9PKT8;C9JZI7 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 EFITGDVEPT(0.021)DAES(0.511)EWHS(0.468)ENEEEEKLAGDMK;EFITGDVEPT(0.012)DAES(0.51)EWHS(0.478)ENEEEEKLAGDMK 52.707 0.0023638 41422100.0 88269.0 57541.2 77424.0 62027.7 69248.1 64689.2 52113.3 64342.2 82922.0 58085.7 True False 87010.26787344782 57407.9668867208 71058.4975852828 66589.42397634135 65175.06290500284 61922.593713890434 54811.471681664756 67331.77350474923 73582.45115262903 68125.73585066984 1.2772011456018983 0.8426766503125609 1.0430492485401042 0.9774488766228367 0.9566878374402471 0.9089456861005281 0.8045633709089078 0.9883456327332603 1.0800977080661587 1.0 16.05591228748056 -4.7491757487115995 24.983873109632075 0.9526401817815131 1.2772018951465953 0.5902435928624936 0.0803099461999159 415.68457721862984 846794.521649826 0.020414609674532052 0.34460370129016665 1.7816576268143285e-05 4.7491757487115995 0.3245617133650822 EFITGDVEPTDAESEWHS(ph)ENEEEEK ddPTM_PC-9_AZD4547_30min_R2 1 EFITGDVEPTDAESEWHSENEEEEK 25 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;A8MXH2;E9PKT8;C9JZI7 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 EFITGDVEPTDAES(0.005)EWHS(0.995)ENEEEEK 98.15100000000001 1.1511e-06 18476000.0 14133.0 19692.0 25757.0 24024.0 26304.0 31203.0 26063.0 30685.0 30232.0 28546.0 True False 18627.000015338086 26057.053901951767 25415.44535067517 18485.6379671 22652.143640090177 29251.871477336845 28382.55650927883 25943.33832115262 31830.001800148737 27546.613228726157 0.6761992794059155 0.9459258633935788 0.9226341234635493 0.6710675397229162 0.8223204592159471 1.0619044611564956 1.0303464993540816 0.9417977486284372 1.1554960145501945 1.0 14.749587334335965 -6.755545961842621 24.586577387476176 1.0337986632461669 0.8141149088315025 0.5847869877542629 0.09691221344321004 89.78454157209117 374568.9041114495 0.03263212983672336 0.03179416212526512 1.7557150751902618e-07 6.755545961842621 -0.21968375441466437 EFITGDVEPTDAESEWHS(ph)ENEEEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EFITGDVEPTDAESEWHSENEEEEK 25 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;A8MXH2;E9PKT8;C9JZI7 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 EFITGDVEPT(0.005)DAES(0.066)EWHS(0.929)ENEEEEK;EFITGDVEPTDAES(0.023)EWHS(0.977)ENEEEEK;EFITGDVEPT(0.003)DAES(0.008)EWHS(0.989)ENEEEEK;EFITGDVEPT(0.023)DAES(0.096)EWHS(0.881)ENEEEEK 99.446 9.8929e-07 44680900.0 60673.4 105907.0 83654.0 91426.0 103940.0 70156.6 98596.0 61940.9 66915.5 75877.5 True False 70944.20826572615 116420.74704502047 85648.62861956168 86303.69762709131 83573.7031395332 66477.46439236424 89256.27310677555 60315.01700680845 67894.01259581151 89633.49010404063 0.7914921998839809 1.2988532178082877 0.9555427164572797 0.9628510228366172 0.9323937184921214 0.7416587741390144 0.9957915618723847 0.6729071570994142 0.7574625568747199 1.0 16.45175025223017 -6.242990338258998 1.4083877788479386 0.8217667500717016 1.0440965734802048 0.2027960752014628 0.15306579669616527 0.5586122323871102 2.228664526306287 0.05601379131729144 0.07941285884690993 5.714913504875476e-07 6.242990338258998 0.22232982340850316 EFITGDVEPTDAESEWHS(ph)ENEEEEK ddPTM_PC-9_Lapatinib_30min_R1 1 EFITGDVEPTDAESEWHSENEEEEK 25 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;A8MXH2;E9PKT8;C9JZI7 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 EFITGDVEPTDAES(0.015)EWHS(0.985)ENEEEEK 71.65100000000001 0.0026819 0.0 788.69 2660.7 2527.1 1100.4 2351.7 1992.9 1060.8 2150.4 2062.0 570.34 True False 777.443135971968 2654.539312622921 2319.3315928880984 1181.3270868267905 2213.3776296200926 1907.6683126768044 1115.723033465737 2250.315434421157 1829.7558461773845 668.9225090697203 1.1622319856647803 3.9683809060553594 3.4672649842709355 1.76601485345392 3.3088700105162663 2.8518524744066767 1.6679406333887439 3.3640898667779946 2.7353778970931195 1.0 9.38569528217205 -10.743481926355395 3.561066736324602 0.997081170435084 2.743249547430423 0.2597897566605556 0.8575117728673702 96832580.19132385 157377129.47599682 3146030.941793898 0.2023968971671432 1.8051698597061838e-11 10.743481926355395 1.7461683769953389 EFITGDVEPTDAESEWHS(ph)ENEEEEKLAGDMK ddPTM_PC-9_AZD4547_30min_R2 3 EFITGDVEPTDAESEWHSENEEEEKLAGDMK 31 1 E9PNJ7;C9J6D1;Q99733;Q99733-2;A8MXH2;E9PKT8;C9JZI7 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 EFITGDVEPT(0.001)DAES(0.073)EWHS(0.926)ENEEEEKLAGDMK;EFITGDVEPT(0.019)DAES(0.143)EWHS(0.838)ENEEEEKLAGDMK;EFITGDVEPTDAES(0.013)EWHS(0.987)ENEEEEKLAGDMK 117.94 1.4066e-17 109640200.0 79196.0 55290.0 121091.0 157911.0 152880.0 123323.0 95305.0 120377.0 113877.0 129223.0 True False 104378.68062086697 73161.41124512049 119485.25422054625 121507.05865062975 131655.2509008891 115611.59331473298 103786.960369751 101775.50063827258 119896.30573549679 124698.94210241993 0.8370454380850869 0.5867043457756864 0.9581897986143982 0.9744032836367725 1.0557848260874234 0.9271256946171751 0.8323002474592517 0.8161697198255342 0.9614861498746433 1.0 16.928089700389748 -5.278777772932798 24.738526188338117 0.9350772589394946 0.7118748887225097 0.5181450955582807 0.0881272525401267 510.65806486489976 728609.77966906 0.024088317687713433 0.050343235171322394 5.262864965832295e-06 5.278777772932798 -0.22320237021698486 EFITGDVEPTDAESEWHS(ph)ENEEEEKLAGDMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EFITGDVEPTDAESEWHSENEEEEKLAGDMK 31 1 E9PNJ7;C9J6D1;Q99733;Q99733-2;A8MXH2;E9PKT8;C9JZI7 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 EFITGDVEPT(0.002)DAES(0.064)EWHS(0.934)ENEEEEKLAGDMK;EFIT(0.005)GDVEPT(0.011)DAES(0.245)EWHS(0.739)ENEEEEKLAGDMK 55.852 0.0007037 29509600.0 14885.1 14213.900000000001 17701.5 25636.9 28317.0 24992.1 26588.0 28576.0 27055.0 23902.8 True False 17404.853435874025 15624.962055607453 18123.570893312586 24200.547608951238 22768.487125285355 23681.470279922425 24069.39215954963 27825.91027877474 27450.628191968623 28236.188425539298 0.6164023689589613 0.5533665458003127 0.6418561393690103 0.8570755813154345 0.8063583789054024 0.838692174844067 0.8524306396035787 0.985469775857089 0.9721789562482114 1.0 14.785257733360247 -5.628634491479258 0.38001792258263356 1.0084134458616698 0.39032591658734395 0.8829562803619541 0.05183951324146041 1.0503958925502248 0.19311981125845276 0.05278898697595316 0.2804131412523276 2.3516111382058786e-06 5.628634491479258 -0.6180875292743259 EFITGDVEPTDAESEWHS(ph)ENEEEEKLAGDMK ddPTM_PC-9_Lapatinib_30min_R1 3 EFITGDVEPTDAESEWHSENEEEEKLAGDMK 31 1 E9PNJ7;C9J6D1;Q99733;Q99733-2;A8MXH2;E9PKT8;C9JZI7 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 EFITGDVEPT(0.006)DAES(0.161)EWHS(0.832)ENEEEEKLAGDMK;EFITGDVEPT(0.002)DAES(0.176)EWHS(0.822)ENEEEEKLAGDMK;EFITGDVEPT(0.003)DAES(0.196)EWHS(0.8)ENEEEEKLAGDMK 113.68 2.6365e-17 76337000.0 244255.0 160700.0 233443.0 184754.0 218470.0 203142.0 175048.0 188683.0 226712.0 199247.0 True False 240771.87890911836 160327.90902337828 214250.21765603893 198341.42548127708 205620.02412854618 194454.09020713088 184111.1289235578 197449.90100115654 201177.30717680266 233686.57847006057 1.030319672124283 0.6860809468521495 0.9168272267013752 0.8487497518249135 0.8798965925845407 0.8321149270968676 0.7878549556800744 0.8449347082483533 0.8608851586338625 1.0 17.834215351344348 -8.816165760692629 3.475707037686833 0.9999981671528807 0.8479069478456743 0.21519019987950705 0.08312798060953559 6.08879277153978 70.93401992960405 0.07336886792359841 0.01933035130656274 1.526983130979928e-09 8.816165760692629 -0.15209121930720637 EFLEDYDDDRDDPK ddPTM_PC-9_AZD4547_30min_R2 1 EFLEDYDDDRDDPK 14 1 P49756 P49756 RBM25 RNA-binding protein 25 0 100.73 0.007640600000000001 0.0 37430.0 29204.0 38584.0 40830.0 35372.0 40316.0 38996.0 39760.0 37516.0 35360.0 False True 49331.961407634975 38643.621884653614 38072.35094966225 31417.27431721169 30461.208365163846 37795.0341467267 42466.56845473802 33616.00559390673 39499.01916956805 34122.05716274634 1.4457499198346824 1.1325114925029727 1.1157695085051538 0.9207321284108371 0.8927131274611624 1.1076423079201223 1.2445488925885166 0.9851693710485865 1.1575802414601235 1.0 15.058417006540559 -4.62296326740588 1.8696069223052623 1.0503986845820243 1.7039559021646697 0.5694226382989636 0.10237463336219656 1.078308234542703 2.7897815910526305 0.029537521407263335 1.41788242840752 2.382520974279028e-05 4.62296326740588 0.6535572175826454 EFLEDYDDDRDDPK ddPTM_PC-9_Lapatinib_30min_R1 1 EFLEDYDDDRDDPK 14 1 P49756 P49756 RBM25 RNA-binding protein 25 0 111.31 0.0005332999999999999 2978300.0 22097.0 40836.0 27956.0 31103.0 36041.0 32282.0 33329.0 34858.0 30732.0 31881.0 False True 21781.89272790648 40741.44675095638 25657.56559328072 33390.41837656642 33921.139239332304 30901.37411301749 35054.612539950554 36477.629935385354 27270.638537693176 37391.58837123774 0.5825345666423064 1.0895885552242388 0.6861854954794315 0.8929927780829688 0.9071863677613929 0.8264258208615541 0.9374999583306061 0.9755571112203562 0.7293254907210689 1.0 15.190426136828323 -4.732923861050191 24.66689010227906 0.8862541143448681 0.5825325558547525 0.3935836897524384 0.11558600854664591 2858.7679194238794 2472773.733967322 0.02669206220368034 2.7199895156007874 1.8495928545360893e-05 4.732923861050191 -0.3037215584901156 EFLHAQEEVKR ddPTM_PC-9_Lapatinib_30min_R1 1 EFLHAQEEVKR 11 1 P43686 P43686 PSMC4 26S protease regulatory subunit 6B 0 65.627 0.017547 3441100.0 58456.0 46875.0 71766.0 46722.0 54614.0 54161.0 41880.0 44648.0 63620.0 43743.0 False True 57622.40672048247 46766.46381749141 65865.6765047711 50158.09174002301 51401.71189525524 51844.660285457576 44048.341479586205 46722.50907553746 56454.445651699854 51303.91926611626 1.123157987630377 0.9115573329770612 1.283833232372018 0.9776658870806775 1.00190614343968 1.0105399553694223 0.8585765397591757 0.9107005808500757 1.1003924545972312 1.0 15.6467814215574 -5.944274849322415 24.999976039442778 0.972985786817062 1.094058715590538 0.23513346351493403 0.10312407197861602 129.32277753378278 58016.91916754805 0.028526311412178176 0.0423113528808028 1.1369075502940828e-06 5.944274849322415 0.12107292877347586 EFLVAGGEDFK ddPTM_PC-9_Lapatinib_30min_R1 2 EFLVAGGEDFK 11 0 Q9Y3F4-2;Q9Y3F4;H0YH33 Q9Y3F4-2 STRAP Serine-threonine kinase receptor-associated protein 0 ; 121.83 0.0033595999999999995 6045300.0 56810.0 54400.0 56124.0 51151.0 62795.0 51641.0 63202.0 45392.0 56134.0 63565.0 False True 55999.878982321956 54274.04014232605 51509.701364905115 54912.8151747339 59101.521559720066 49432.43481105065 66474.29031023897 47501.07803164303 49811.597802774595 74552.1255549616 0.7511506689509142 0.7280012439392346 0.6909219687764762 0.7365694105428404 0.7927543463016224 0.6630586913931499 0.8916484917822033 0.6371525651086112 0.6681445690780781 1.0 16.1859618653095 -11.306537578489209 2.510265727059154 1.0773254508430103 0.7299503681920857 0.5744659331387263 0.07001199368195465 14337414.239879493 9825607.294677606 6786987.465048519 0.017391627446180166 4.936991977606521e-12 11.306537578489209 -0.34737508265092465 EFMQHAR ddPTM_PC-9_AZD4547_30min_R2 1 EFMQHAR 7 0 A0A0G2JMS5;A0A087WU62;A0A087X2D5;Q9BRJ2 A0A0G2JMS5 MRPL45 39S ribosomal protein L45, mitochondrial 0 68.915 0.024372 0.0 1038.5 586.35 1218.0 3683.8 3045.5 1884.1 949.0 1084.0 953.44 1061.1 False True 1368.7213978581055 775.8761708008032 1201.848524172938 2834.5568241426504 2622.6848941565786 1766.2869291558627 1033.4591615433994 916.4927078419234 1003.8368919136617 1023.9512119737036 1.3367056768455254 0.7577276746469915 1.1737361215250977 2.76825379080214 2.5613377507520667 1.7249717647692215 1.0092855494075434 0.8950550545033782 0.9803561733949503 1.0 9.999931261796478 -7.2700118386290855 6.07011732908601 0.9581517480845192 1.7391464616028263 0.2970201653727639 0.5645360114250007 0.24240825205959854 40.22826491555233 0.27100733394880433 0.19156871148444063 5.37017157377919e-08 7.2700118386290855 0.7809947135183071 EFMQHAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EFMQHAR 7 0 A0A0G2JMS5;A0A087WU62;A0A087X2D5;Q9BRJ2 A0A0G2JMS5 MRPL45 39S ribosomal protein L45, mitochondrial 0 55.504 0.044358999999999996 0.0 2128.1 1009.2 734.64 439.55 644.17 1217.9 2159.1 1282.3 974.15 592.16 False True 2488.3452981090836 1109.3867064295537 752.1566037377147 414.9234385403273 517.9495127130368 1154.0311800095842 1954.5744174696706 1248.6409837091564 988.3951008392627 699.5139204640187 3.5572491487495395 1.5859394273292633 1.0752560910278608 0.5931596590173503 0.7404420377645349 1.6497615647792454 2.794189451116447 1.7850123452595157 1.4129741695256275 1.0 9.450208957364293 -8.571687769454167 4.479726905229673 1.0003799730730312 1.6575139176280511 0.061856275001763716 0.8506386239999904 0.940870919449081 61.05620735259321 0.8771239109941383 0.22884587321071317 2.6810951716878905e-09 8.571687769454167 0.6571339445550199 EFNAEVHR ddPTM_PC-9_AZD4547_30min_R2 4 EFNAEVHR 8 0 P46777;A0A2R8Y6J3 P46777 RPL5 60S ribosomal protein L5 0 ;;; 137.05 0.0027730999999999997 33965100.0 123751.0 126885.0 156774.0 167560.0 151573.0 154422.0 147637.0 180485.0 148781.0 150190.0 False True 163101.24381929557 167898.09487858755 154695.0743256881 128931.63077619369 130529.70529042704 144765.96792851048 160776.4069892337 152595.19038270295 156645.2599175684 144931.8938142781 1.125364745652882 1.1584620228156222 1.0673639200762874 0.8896015044239481 0.9006278870384 0.998855145810899 1.109323853832059 1.052875156507959 1.0808197960781516 1.0 17.14501558475257 -5.5217154583001955 24.987093764765795 1.0044214397977018 1.1346633037917482 0.4075751719971762 0.06621863944431697 45.290507412442714 972826.9559329788 0.020668555512296877 0.036407145267320695 3.0080464734773185e-06 5.5217154583001955 0.13024186399404636 EFNAEVHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EFNAEVHR 8 0 P46777;A0A2R8Y6J3 P46777 RPL5 60S ribosomal protein L5 0 ;;; 143.37 0.0014971 29325100.0 180360.0 227587.0 208198.0 207946.0 222082.0 175436.0 196591.0 164101.0 166653.0 155979.0 False True 210891.38572762292 250180.3332899161 213162.22991531168 196295.45979002787 178566.6263289764 166235.82732257267 177968.4772844152 159793.52262938197 169089.98484849886 184256.75797091582 1.1445517008440542 1.3577810444781953 1.1568760476560564 1.0653365550967326 0.9691184643396494 0.9021966366564006 0.965872184251211 0.8672329003780949 0.9176867470727398 1.0 17.491358008342395 -5.908775933388312 1.5915407919568059 0.9254742437707064 1.2542084417425867 0.8143153922775734 0.06122143578336475 0.14033700893797535 0.722872264659401 0.01941218811378524 0.0363173740774632 1.2337411961602066e-06 5.908775933388312 0.3287341979718803 EFNAEVHR ddPTM_PC-9_Lapatinib_30min_R1 4 EFNAEVHR 8 0 P46777;A0A2R8Y6J3 P46777 RPL5 60S ribosomal protein L5 0 ;;; 168.26 0.00048127 45095100.0 174526.0 222268.0 231421.0 220632.0 247065.0 233654.0 230619.0 244406.0 245381.0 204334.0 False True 172037.22723585166 221753.35210210568 212394.45869089334 236858.01328677568 232533.12244847894 223661.1630940769 242559.32339256667 255761.99500796935 217743.60780351728 239652.85964205978 0.717860106041725 0.9253106866044144 0.8862588120505678 0.9883379386356649 0.9702914573845907 0.9332714136110551 1.0121278075081095 1.0672186235956869 0.9085792179936193 1.0 17.87058662936053 -3.9397445981410852 0.8192483919141964 0.985974084298811 5.160303038825414e-15 0.7178302164842697 0.04801826583474971 4.448208313019185 0.8380091850534819 0.016850643816131133 5.511096830877177 0.00011488290314398972 3.9397445981410852 -0.9859740842988058 EFNAEVHRK ddPTM_PC-9_AZD4547_30min_R2 2 EFNAEVHRK 9 1 P46777;A0A2R8Y6J3 P46777 RPL5 60S ribosomal protein L5 0 ; 66.27 0.019400999999999998 22090000.0 94272.0 63336.0 104741.0 167912.0 135092.0 113566.0 91226.0 114649.0 95515.0 114556.0 False True 124248.53502058689 83808.12339701499 103352.06590344648 129202.4826145394 116336.80765765898 106464.7000671488 99344.93727182088 96932.63142192694 100563.72790226275 110545.42930813282 1.1239590437905689 0.7581328682835847 0.9349284411874175 1.1687727246904271 1.0523891253195403 0.9630855000833237 0.8986797364087135 0.8768578857452193 0.9097049831156093 1.0 16.754279850103742 -7.056284160396718 4.796754669207903 0.9122913349818689 0.999581552649415 0.11803312637543095 0.10889334621671719 0.5137579622477562 24.75636590466682 0.044552716281261305 0.03501228365763676 8.784475574467341e-08 7.056284160396718 0.08729021766754608 EFPDVLECTVSHAVEK ddPTM_PC-9_Lapatinib_30min_R1 1 EFPDVLECTVSHAVEK 16 0 P48507 P48507 GCLM Glutamate--cysteine ligase regulatory subunit 0 143.93 7.1143e-08 0.0 26076.0 20237.0 22650.0 23100.0 22220.0 21038.0 18809.0 18042.0 18730.0 16456.0 False True 25704.15145824725 20190.142469857576 20787.804431528413 24798.85105934101 20913.063286200802 20138.253781973304 19782.83798685617 18880.297185559215 16620.43016435616 19300.397673758303 1.3317938776565097 1.0460998167570925 1.0770661197200333 1.2848880877236355 1.0835560820922956 1.043411339101794 1.0249963923672836 0.9782335838203854 0.8611444409227925 1.0 14.236342953262927 -7.070403882524601 1.0742128099686123 0.9388836788614624 1.1692385900184743 0.5430135051475931 0.08945157915982367 0.4215212987477532 0.9867631946565755 0.05743052402188636 0.03859769002779755 8.503468699980796e-08 7.070403882524601 0.2303549111570119 EFPGFLENQKDPLAVDK ddPTM_PC-9_AZD4547_30min_R2 2 EFPGFLENQKDPLAVDK 17 1 P60903 P60903 S100A10 Protein S100-A10 0 ; 109.04 0.0006279 37315000.0 70909.0 86535.0 98773.0 116552.0 105773.0 93206.0 92507.0 112149.0 94422.0 102319.0 False True 93456.58700117512 114505.74646584387 97463.20548286819 89682.73711044967 91088.24472488042 87377.81408571795 100739.94379019499 94818.94897764202 99412.95415366646 98736.84295347956 0.9465219284478008 1.1597063774845822 0.9871006867090996 0.9083006345737044 0.9225355196721976 0.8849565316453001 1.0202872684278472 0.9603198374725889 1.0068476080454127 1.0 16.591300896127606 -5.50965631881637 24.696183877061916 0.9535862512329649 1.0581865100819374 0.2605090334178154 0.06323417649427425 591.5644116603645 1104892.5637899723 0.016246583854236146 0.03152923726683065 3.092741921674706e-06 5.50965631881637 0.1046002588489725 EFPGFLENQKDPLAVDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EFPGFLENQKDPLAVDK 17 1 P60903 P60903 S100A10 Protein S100-A10 0 ; 122.31 7.7842e-05 36801000.0 66167.0 67446.0 72499.0 91175.0 102075.0 82711.0 82230.0 81521.0 74974.0 63281.0 False True 77367.76624218015 74141.59314491454 74227.6511139885 86066.76034333833 82074.13650151867 78373.48955560602 74440.57910635497 79381.16012863915 76070.35291312706 74753.34436787966 1.034973978708354 0.9918164032908743 0.9929676289624703 1.1513432752892307 1.0979326369347648 1.048427869259076 0.9958160365376364 1.0619078089400906 1.0176180551704292 1.0 16.189850504613013 -10.476147214081072 14.821416455218086 1.000001984053504 1.0446653746615566 0.0684429236174452 0.04817306590764348 0.0 0.0 0.05047147463397247 0.01224113064685594 3.340817761457843e-11 10.476147214081072 0.04466339060805269 EFPGFLENQKDPLAVDK ddPTM_PC-9_Lapatinib_30min_R1 3 EFPGFLENQKDPLAVDK 17 1 P60903 P60903 S100A10 Protein S100-A10 0 ;; 119.56 0.00012623 47148000.0 107885.0 89932.0 97800.0 92369.0 97644.0 90681.0 101978.0 92917.0 109453.0 84221.0 False True 106346.5401163139 89723.76797940553 89759.26151891716 99162.12439395094 91900.77189549025 86802.78501773566 107257.92185781366 97234.26303018548 97125.25054881345 98778.48763257178 1.0766164036838988 0.908333080712399 0.9086924053018143 1.003883808818841 0.9303723320540734 0.8787620371413017 1.0858429241879366 0.9843667924120242 0.9832631869207402 1.0 16.59190925976923 -7.259328044926414 24.99627953574237 1.0120654554923887 0.9486937223447465 0.20899212550202273 0.059203750550186084 306.6190523288226 3630122.260427783 0.023238988862112467 0.017080211317129435 5.503918001579332e-08 7.259328044926414 -0.06337173314764222 EFQEHCR ddPTM_PC-9_Lapatinib_30min_R1 1 EFQEHCR 7 0 Q13111;Q13111-3 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 0 71.877 0.030492000000000002 0.0 2889.6 4757.2 5458.6 4602.5 3746.0 3502.5 4226.8 4237.1 3442.1 3109.7 False True 2848.3937741122595 4746.184995681496 5009.814978805341 4940.983203489917 3525.6676449193606 3352.7062397262807 4445.64302210876 4433.971134294033 3054.414451080102 3647.207501585209 0.780979358282808 1.3013202549124587 1.3736029487293753 1.354730489379172 0.9666759139388087 0.9192529457863511 1.21891694403911 1.2157167181650257 0.8374665959511606 1.0 11.832576566319103 -6.273186441255515 24.66894817334706 1.0413986993574706 1.2219158882859822 0.16353724570283001 0.19159423808680048 1190.4025377059074 2499852.5265321075 0.061209599348038476 0.06997033429236069 5.331059856326266e-07 6.273186441255515 0.18051718892851154 EFS(ph)GGSYSAK ddPTM_PC-9_AZD4547_30min_R2 2 EFSGGSYSAK 10 0 H0Y7V8;A0A0A0MRJ1;H0Y5V1;A0A0A0MRJ0;Q5VT25-3;Q5VT25-4;Q5VT25-5;Q5VT25;Q5VT25-2;Q5VT25-6 H0Y7V8 CDC42BPA Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase MRCK alpha 1 EFS(0.993)GGS(0.006)YS(0.001)AK;EFS(0.998)GGS(0.002)YSAK 117.79 0.00092722 21462300.0 63033.0 60728.0 61845.0 92724.0 85741.0 77810.0 62037.0 91274.0 62670.0 74105.0 True False 83076.182832152 80357.13839923454 61024.89489119486 71347.91437151945 73837.34214739093 72944.52839956338 67558.17281840659 77169.70056786331 65982.60825665928 71510.60650580653 1.1617323204412533 1.1237093674028578 0.8533684424315399 0.9977249230255952 1.0325369306075662 1.0200518771105713 0.9447294061604832 1.0791364293854406 0.9226968065401825 1.0 16.125869618901646 -5.067957233354335 9.988426340117071 0.9866058373430495 1.15233502831394 0.5406656561723431 0.059810570402368056 0.3515633452743938 50.44505274887307 0.01478888771916339 0.039358763490155144 8.55150918733998e-06 5.067957233354335 0.16572919097089045 EFS(ph)GGSYSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EFSGGSYSAK 10 0 H0Y7V8;A0A0A0MRJ1;H0Y5V1;A0A0A0MRJ0;Q5VT25-3;Q5VT25-4;Q5VT25-5;Q5VT25;Q5VT25-2;Q5VT25-6 H0Y7V8 CDC42BPA Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase MRCK alpha 1 EFS(0.774)GGS(0.222)YS(0.004)AK;EFS(0.983)GGS(0.014)YS(0.003)AK 96.103 0.0056602 15077300.0 52149.0 52621.0 54066.0 52751.0 64823.0 54406.0 56452.0 46952.0 48010.0 44976.0 True False 60976.79571030052 57844.86511992623 55355.13848644683 49795.532491049475 52121.398485799094 51552.85358371083 51104.457882913164 45719.559749756154 48712.05542400344 53129.792770179876 1.1476949660629003 1.0887462966426773 1.0418850818013348 0.9372431152977917 0.9810201728295322 0.970319116558758 0.9618794882933654 0.8605258437111228 0.9168500926535521 1.0 15.69723346521914 -4.925853980438436 0.6816209523712928 0.931012663750386 1.2655333133162046 0.7683517665349889 0.03837228598118429 1.2588816204070237 0.5045986119208931 0.018075992830444275 0.31710161953440696 1.1861674972899191e-05 4.925853980438436 0.3345206495658185 EFSGGSYS(ph)AK ddPTM_PC-9_Lapatinib_30min_R1 1 EFSGGSYSAK 10 0 H0Y7V8;A0A0A0MRJ1;H0Y5V1;A0A0A0MRJ0;Q5VT25-3;Q5VT25-4;Q5VT25-5;Q5VT25;Q5VT25-2;Q5VT25-6 H0Y7V8 CDC42BPA Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase MRCK alpha 1 EFS(0.022)GGS(0.45)Y(0.012)S(0.516)AK 80.834 0.017112 7106100.0 34182.0 24334.0 26208.0 28450.0 20988.0 17401.0 20528.0 21078.0 22137.0 21587.0 True False 33694.558411788916 24277.6561180765 24053.279405805588 30542.307906417846 19753.52710399562 16656.7997937122 21590.83939572457 22057.360829022116 19643.697947055633 25318.284187130554 1.3308389369022122 0.9588981598688661 0.9500359198129241 1.2063340343554045 0.7802079697816358 0.657896075049942 0.8527765640097892 0.8712028297807801 0.7758700313918054 1.0 14.627892016598707 -6.272807258907957 24.819527898412574 0.8097867804085946 1.089089659799254 0.5287184804564569 0.13242805849450018 548.9788264415746 1198584.9686188796 0.04076737333349786 0.046644231195972746 5.33571643519924e-07 6.272807258907957 0.27930287939065945 EFSGPST(ph)PTGTLEFEGGEVSLEGGK ddPTM_PC-9_AZD4547_30min_R2 2 EFSGPSTPTGTLEFEGGEVSLEGGK 25 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 EFSGPS(0.181)T(0.816)PT(0.002)GTLEFEGGEVSLEGGK;EFS(0.002)GPS(0.165)T(0.732)PT(0.101)GTLEFEGGEVSLEGGK 184.94 2.0927e-20 41641000.0 84477.0 112005.0 109158.0 111929.0 119421.0 136399.0 149601.0 222539.0 186633.0 128745.0 True False 111338.92876924349 148208.42587284706 107710.49359742976 86125.49833581157 102841.45550650873 127869.94896764016 162915.19918446185 188150.7109874855 196498.03936117873 124237.67673692785 0.8961768417885233 1.1929426705771153 0.8669712475830158 0.6932317200214676 0.827779931238368 1.0292364790304604 1.3113187839904097 1.514441640645719 1.5816300217627342 1.0 16.92274323091462 -7.2326225871507575 2.7453639032375827 1.4105351493187477 0.901080422804597 0.5694478676369942 0.18636660605100433 0.1964548179128039 2.9447045970878354 0.0856128126841623 0.0590531141710132 5.8529850234676434e-08 7.2326225871507575 -0.5094547265141507 EFSGPST(ph)PTGTLEFEGGEVSLEGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EFSGPSTPTGTLEFEGGEVSLEGGK 25 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 EFS(0.018)GPS(0.078)T(0.386)PT(0.382)GT(0.137)LEFEGGEVSLEGGK;EFS(0.003)GPS(0.035)T(0.476)PT(0.476)GT(0.01)LEFEGGEVSLEGGK;EFS(0.004)GPS(0.156)T(0.553)PT(0.243)GT(0.043)LEFEGGEVSLEGGK;EFS(0.007)GPS(0.215)T(0.714)PT(0.054)GT(0.009)LEFEGGEVSLEGGK 129.8 9.4055e-08 29215700.0 161381.5 196394.0 168280.0 162635.0 286386.0 219895.0 296734.0 246076.0 232461.0 224162.0 True False 188700.20052008436 215890.6983972712 172292.43340545407 153523.08821978403 230270.7191391025 208363.31909697605 268625.2073518809 239616.76573907354 235860.30235199467 264800.7961345848 0.7126119077987123 0.8152947481605942 0.6506492273455499 0.5797682275160382 0.8695997991715537 0.7868681746374945 1.014442597126303 0.9048944309717577 0.8907084336412601 1.0 18.014547934110986 -6.766450811942894 1.7122284534647694 0.9395068690165024 0.7017755154794446 0.6430344963531313 0.08101253591463599 0.24068453899618666 1.460429395701807 0.03503820270037092 0.031830832413243054 1.7121790865890783e-07 6.766450811942894 -0.23773135353705777 EFSGPST(ph)PTGTLEFEGGEVSLEGGK ddPTM_PC-9_Lapatinib_30min_R1 2 EFSGPSTPTGTLEFEGGEVSLEGGK 25 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 EFS(0.004)GPS(0.204)T(0.782)PT(0.01)GTLEFEGGEVSLEGGK;EFS(0.009)GPS(0.147)T(0.682)PT(0.147)GT(0.015)LEFEGGEVSLEGGK 135.57 3.85e-07 27383000.0 126268.0 165116.0 125722.0 114625.0 201871.0 198101.0 232667.0 210066.0 209798.0 229955.0 True False 124467.39516528454 164733.68404669693 115385.62246095458 123054.90487779079 189997.34467365642 189628.6820259858 244713.3588116257 219826.43324363636 186168.3399691185 269702.4153542235 0.46149900067380095 0.6107979560744309 0.42782569191828945 0.4562617828845624 0.7044703119329372 0.7031033881432988 0.9073458185023018 0.8150703172417618 0.6902731654242232 1.0 18.041008916306794 -6.591400558139695 1.7622299904364038 0.8307954321001689 0.49315189135358634 0.7374624535142914 0.09443672146700664 0.18777225651543442 1.1917358599595427 0.036547604017411986 0.03789684422021423 2.562119854082335e-07 6.591400558139695 -0.3376435407465826 EFT(ph)GSPPSSATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EFTGSPPSSATK 12 0 Q92609;Q92609-2;C9J3F6 Q92609 TBC1D5 TBC1 domain family member 5 1 EFT(0.893)GS(0.084)PPS(0.02)S(0.003)ATK 79.492 0.037471 26193000.0 74201.0 108700.0 80482.0 75171.0 99696.0 69729.0 91357.0 75195.0 65183.0 64610.0 True False 86761.76376344736 119491.01762672645 82400.99610968454 70959.4125776703 80161.28447372415 66072.28848911094 82703.00359259732 73221.21092568825 66136.17806087939 76323.28154752144 1.136766685135604 1.5655906717313683 1.0796312008463487 0.9297217197545231 1.050286136135447 0.865689828181354 1.083588151815821 0.9593561681450798 0.8665269197014385 1.0 16.21983558142954 -5.461046628665296 6.147784416656233 0.9699693553683546 1.3494419027190758 0.6310828677458572 0.11652404700900855 0.12405986292361479 9.429049898042098 0.028330413808199874 0.05905595213358251 3.4590223753026997e-06 5.461046628665296 0.3794725473507212 EFTGS(ph)PPSSATK ddPTM_PC-9_AZD4547_30min_R2 1 EFTGSPPSSATK 12 0 Q92609;Q92609-2;C9J3F6 Q92609 TBC1D5 TBC1 domain family member 5 1 EFT(0.002)GS(0.888)PPS(0.103)S(0.006)ATK 113.52 0.00082372 25801000.0 52710.0 63419.0 80734.0 67598.0 57292.0 65458.0 75382.0 70625.0 65628.0 65359.0 True False 69470.68356389093 83917.95152386144 79663.41440934144 52014.325478689134 49337.99473190567 61364.90091220443 82090.8519657162 59711.5290510479 69096.96209778254 63070.80130373134 1.1014713960797728 1.3305356803655632 1.263079154896173 0.8246973940952912 0.7822636420030195 0.9729526126786978 1.3015666563421258 0.9467380755715132 1.0955459684907267 1.0 15.944684642068411 -5.7386591546198655 24.99950101568692 0.9906172416554816 1.2415796029809194 0.3710289049361285 0.14455844595910602 267.964742349014 294067.92987375206 0.04232090420847533 0.07323819259934605 1.825327704022532e-06 5.7386591546198655 0.2509623613254378 EFTGS(ph)PPSSATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EFTGSPPSSATK 12 0 Q92609;Q92609-2;C9J3F6 Q92609 TBC1D5 TBC1 domain family member 5 1 EFT(0.487)GS(0.497)PPS(0.014)S(0.002)ATK 177.93 0.00032148 28548000.0 195830.0 279530.0 263920.0 216640.0 253320.0 191460.0 263170.0 209580.0 194630.0 174810.0 True False 228980.15118119543 307279.891050588 270212.853722174 204502.36315635685 203683.76447283526 181419.50055393277 238240.6324141971 204078.74706836545 197476.09554621525 206501.66920480158 1.1088537543689316 1.488026185133825 1.3085262446677164 0.9903182087769863 0.9863540825465599 0.878537695373333 1.1536983373142513 0.988266815731968 0.9562929748057626 1.0 17.65579391779464 -5.75513358728215 7.788482865797648 0.9941675528416701 1.3215156047130072 0.6365112911359996 0.10651812959413891 0.07371582061556631 30.22185596559726 0.02850500722474127 0.04655532998952257 1.757382966692957e-06 5.75513358728215 0.3273480518713371 EFTGS(ph)PPSSATK ddPTM_PC-9_Lapatinib_30min_R1 2 EFTGSPPSSATK 12 0 Q92609;Q92609-2;C9J3F6 Q92609 TBC1D5 TBC1 domain family member 5 1 EFT(0.035)GS(0.424)PPS(0.257)S(0.257)AT(0.028)K;EFT(0.005)GS(0.749)PPS(0.223)S(0.023)ATK 126.1 0.00027360000000000004 69223000.0 81356.0 122517.0 126972.0 104756.0 148912.0 161887.0 140701.0 146126.0 132348.0 122174.0 True False 80195.84852113687 122233.31941392228 116532.85228609387 112460.10569577185 140153.2889322564 154963.4703870287 147985.80932471968 152915.54741919026 117441.57455377506 143291.6131133781 0.5596688234480457 0.8530388957042891 0.8132566153323181 0.7848338311802582 0.9780983400707582 1.0814552716662864 1.0327597415462646 1.0671632770174575 0.8195983840369678 1.0 17.128594645280202 -6.256760776240259 3.286302614818759 1.0092711217703514 0.7584249716654597 0.5969045701020887 0.09833062239302207 0.17950460887531838 4.064956396292631 0.031043900475423367 0.038683904213601086 5.536549967146949e-07 6.256760776240259 -0.25084615010489164 EFTGS(ph)PPSSATKK ddPTM_PC-9_Lapatinib_30min_R1 1 EFTGSPPSSATKK 13 1 Q92609;Q92609-2;C9J3F6 Q92609 TBC1D5 TBC1 domain family member 5 1 EFT(0.085)GS(0.787)PPS(0.014)S(0.016)AT(0.098)KK 51.875 0.044012 102000000.0 54083.0 33261.0 43408.0 34959.0 39446.0 38133.0 24845.0 34080.0 41767.0 27560.0 True False 53311.766502392486 33183.986198049766 39839.161799725625 37530.00147980534 37125.86383381985 36502.14048236465 26131.35253248135 35663.48121515674 37062.760633991624 32323.709278608334 1.6493084392908441 1.0266144244779098 1.2325058815601642 1.161067288296721 1.1485644643633013 1.1292683079080155 0.8084267899839993 1.1033226696775995 1.1466122379252919 1.0 14.980305142329646 -4.757544883675239 24.996543059055213 1.0891344056618255 1.649309246034383 0.696804703795539 0.11181587833556587 67.95181381604726 436082.49620633066 0.029159211263826524 0.21471628930688183 1.7476526358384924e-05 4.757544883675239 0.5601748403725575 EFTGSPPS(ph)SATK ddPTM_PC-9_AZD4547_30min_R2 2 EFTGSPPSSATK 12 0 Q92609;Q92609-2;C9J3F6 Q92609 TBC1D5 TBC1 domain family member 5 1 EFT(0.001)GS(0.366)PPS(0.497)S(0.128)AT(0.009)K;EFT(0.027)GS(0.219)PPS(0.36)S(0.36)AT(0.034)K 83.53 0.010922 74960000.0 96838.0 112103.0 112628.0 123183.0 130262.0 129690.0 109689.0 140529.0 126056.0 129037.0 True False 127630.4696444711 148338.10245635262 111134.47913017221 94785.06250837837 112177.36978579048 121580.46379821895 119451.10850425066 118813.4720851639 132719.0628115755 124519.4539058058 1.0249841742882897 1.1912845567774872 0.8925069589065271 0.7612068599343492 0.9008822819818048 0.9763973418176882 0.9592967585178365 0.9541759810080901 1.0658500230170653 1.0 16.926011629267613 -10.52660175754291 21.310407277892374 0.9999999998529887 0.9651617357176232 0.005580044037225118 0.10776727949162096 0.0 0.0 0.11413526856153494 0.027681868699261605 2.9743922610562284e-11 10.52660175754291 -0.034838264135365504 EFTMNNYFS(ph)VGPDALMALNFHAHREK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EFTMNNYFSVGPDALMALNFHAHREK 26 1 I3L112;P52429 I3L112 DGKE Diacylglycerol kinase;Diacylglycerol kinase epsilon 1 EFT(0.079)MNNY(0.438)FS(0.483)VGPDALMALNFHAHREK 52.909 0.026177999999999996 0.0 4602.0 2886.1 4934.2 5871.3 4812.9 5548.3 5453.0 4972.6 4108.8 5500.7 True False 5381.027706356843 3172.6129344295814 5051.850041057705 5542.350096011428 3869.8467946917362 5257.337380776067 4936.452363698812 4842.074518905208 4168.88342691409 6497.933366482762 0.8281137098316408 0.4882495334277137 0.7774548854434005 0.8529404325073008 0.5955503967850672 0.8090783768104086 0.7596957502152478 0.745171463881316 0.6415706643619595 1.0 12.665765234187013 -11.246415298673472 2.7526334379409945 1.0482963049025484 0.7212240137109602 0.37062331082885147 0.10868491258563656 109029880.33356507 90027918.40532707 36166706.907309435 0.025930415097324338 5.670021443091332e-12 11.246415298673472 -0.3270722911915882 EFVISDR ddPTM_PC-9_AZD4547_30min_R2 2 EFVISDR 7 0 Q14019;H3BT58 Q14019 COTL1 Coactosin-like protein 0 ; 153.73 0.0022078 24344000.0 85547.0 117861.0 115884.0 130088.0 127577.0 139331.0 120406.0 150820.0 113400.0 108990.0 False True 112749.16651186068 155957.26335252554 114347.30244273963 100098.22143956496 109865.13568931662 130618.6105441405 131121.9007426704 127514.23449881842 119394.09248931159 105174.29327397411 1.0720220978158073 1.4828458409153666 1.087217217090019 0.9517365729172411 1.0446006554389018 1.2419252507253378 1.2467105474253484 1.212408760063163 1.135202232149025 1.0 16.68242259828577 EFVISDR ddPTM_PC-9_Lapatinib_30min_R1 3 EFVISDR 7 0 Q14019;H3BT58 Q14019 COTL1 Coactosin-like protein 0 ;; 143.11 0.0092121 37992000.0 177838.0 210841.0 215085.0 189089.0 229911.0 213935.0 225281.0 203046.0 215701.0 176800.0 False True 175301.99750850518 210352.8106185322 197401.54155211005 202995.23584241275 216388.08700241748 204785.49875684257 236944.94787160147 212480.25841586632 191406.48194777276 207359.64442880813 0.8454007431937455 1.014434661083496 0.9519766591800993 0.9789524687968213 1.043540017627244 0.9875860817612014 1.1426762836341124 1.0246943613409611 0.9230652496295513 1.0 17.66177562390415 -3.774161541459134 0.9916856190439416 1.0182288227953826 4.1033816425566063e-35 0.3958054074980498 0.057659173960444045 12.740278718604326 2.2102230524623474 0.018891348408424474 22.105903312290902 0.00016820482850431938 3.774161541459134 -1.0182288227953826 EFVISDRK ddPTM_PC-9_AZD4547_30min_R2 1 EFVISDRK 8 1 Q14019;H3BT58 Q14019 COTL1 Coactosin-like protein 0 91.853 0.0053237 17655000.0 44336.0 33463.0 54933.0 75109.0 64820.0 51103.0 49260.0 52015.0 35312.0 38092.0 False True 58433.92575391138 44279.260345369265 54204.552527415406 57793.78047248225 55820.86187464435 47907.5213314856 53644.044570735314 43977.27693579122 37178.520229123205 36758.410674302446 1.5896749800110956 1.2046021450085325 1.4746163267964532 1.5722600464030805 1.518587470204971 1.303307745157149 1.4593678993917303 1.1963867895554972 1.0114289368640863 1.0 15.16578676962931 -7.9863940987410755 2.092016519493992 0.9938557887066053 1.4440699621246589 0.7202021191935208 0.11144882613044658 0.18126077874901314 1.4637310908771812 0.092858182523968 0.031637727168138535 1.0318246557613877e-08 7.9863940987410755 0.4502141734180536 EFVISDRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EFVISDRK 8 1 Q14019;H3BT58 Q14019 COTL1 Coactosin-like protein 0 ; 131.22 0.002495 19057200.0 83853.0 57820.0 75009.0 89241.0 106565.0 111277.0 79900.0 85992.0 96373.0 76615.0 False True 98047.65672775738 63559.987480932214 76797.49903321669 84241.11609322559 85684.35323325307 105441.43822803724 72331.29357409423 83734.80111605542 97782.27280519661 90504.69301599365 1.083343343426741 0.7022838856511024 0.8485471468274616 0.9307927941188511 0.9467393388993791 1.1650383501041657 0.7991993692670956 0.9251984435907442 1.0804110764501118 1.0 16.46570498296471 -6.025566653114756 2.8272774978453152 0.9814303612497377 0.8620206744331255 0.12643608434672304 0.1250074857606105 0.5273619624396902 8.477196098905946 0.03806878202654447 0.055737060950661 9.428299000376936e-07 6.025566653114756 -0.11940968681661224 EFYGEDAKK ddPTM_PC-9_Lapatinib_30min_R1 1 EFYGEDAKK 9 1 P30838;I3L3I9;C9JMC5;E9PNN6 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 0 62.582 0.038641 14624000.0 42851.0 49448.0 52392.0 45459.0 52204.0 45740.0 55198.0 48082.0 44079.0 45422.0 False True 42239.93688208902 49333.506194076035 48084.53199896852 48802.206506778486 49133.463357012944 43783.806825147774 58055.88235411176 50316.06525197085 39114.35884755231 53273.13217898945 0.7928938125914842 0.92604853847007 0.9026038085654878 0.9160754119508245 0.9222934966904544 0.8218740861348452 1.089777904536437 0.9444923396453712 0.7342229984926386 1.0 15.701120485795846 -4.759108317800124 24.658751759876438 0.9177900931923246 0.7928936281304788 0.1482422753711462 0.0895935784318843 104.83581177328524 1108692.5730609854 0.02181222051182017 0.14162331612712886 1.7413725018521054e-05 4.759108317800124 -0.12489646506184582 EGAAGS(ph)PGGPR ddPTM_PC-9_AZD4547_30min_R2 2 EGAAGSPGGPR 11 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6;P53814-2;H7BZZ8;B5MCI0 A0A087WVP4 SMTN Smoothelin 1 EGAAGS(1)PGGPR;EGAAGS(1)PGGPR 87.713 0.010223000000000001 17669900.0 26982.0 27279.0 35171.0 45963.0 34425.0 31872.0 31401.0 37188.0 32782.0 32522.0 True False 35561.7147395353 36096.403280080354 34704.60955967684 35366.94047127112 29645.682968753954 29879.038801579354 34195.62816820259 31441.449095226446 34514.789594220594 31383.41467892638 1.1331372033080456 1.150174499791404 1.1058264345906441 1.1269309230081848 0.9446289790976986 0.9520646209873014 1.0896082697834846 1.001849206560019 1.0997780180178067 1.0 14.937714713128177 -6.232643626022267 22.88449052586863 1.0153654817705249 1.128872088730208 0.5763147222060334 0.04803515707364502 194.1523037529171 154295.57657194868 0.014663455768749917 0.018924404051446044 5.852701489546888e-07 6.232643626022267 0.11350660695968307 EGAAGS(ph)PGGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EGAAGSPGGPR 11 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6;P53814-2;H7BZZ8;B5MCI0 A0A087WVP4 SMTN Smoothelin 1 EGAAGS(1)PGGPR;EGAAGS(1)PGGPR 80.737 0.015835 17729500.0 40815.0 46833.0 39208.0 36398.0 41451.0 36578.0 44826.0 32305.0 33731.0 28334.0 True False 47724.17336700445 51482.27073148559 40142.867417168025 34358.73806390817 33328.97410849324 34659.78528811113 40579.75676786414 31457.027979976843 34224.25206221746 33470.72990817942 1.425848002058116 1.5381281159005915 1.1993424561487707 1.0265308870814838 0.9957647831381311 1.0355252300500664 1.2123953340481963 0.9398369281540383 1.0225128688888825 1.0 15.030612392283743 -5.451614050524766 3.0975169299713015 1.0378027305976434 1.482252822939716 0.857245011052281 0.07238547896145606 0.08726320069379255 1.6173213067759062 0.02032843631770782 0.046663761375816404 3.534971766493801e-06 5.451614050524766 0.44445009234207267 EGAAGS(ph)PGGPR ddPTM_PC-9_Lapatinib_30min_R1 2 EGAAGSPGGPR 11 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6;P53814-2;H7BZZ8;B5MCI0 A0A087WVP4 SMTN Smoothelin 1 EGAAGS(1)PGGPR;EGAAGS(1)PGGPR 102.05 0.003481 18122400.0 29577.0 34767.0 37664.0 29243.0 28381.0 25541.1 27162.0 25048.9 30464.0 22673.8 True False 29155.226556242487 34686.499147578106 34567.41130724443 31393.627771788302 26711.685379192844 24448.7666922121 28568.315455313306 26212.763339505265 27032.823519858284 26592.936119060585 1.096352295425753 1.30435010982922 1.2998719341287068 1.1805250699371554 1.0044654437404203 0.9193707149429188 1.0742821073765096 0.9857039938029698 1.01654151308559 1.0 14.698755453117949 -6.182491575352721 3.6204514868612625 0.998075928068467 1.2401399103870032 0.7404038574680617 0.06429558189689326 0.11795439180758377 2.9782947827616386 0.01967287919085745 0.02571203141026535 6.569138594746505e-07 6.182491575352721 0.2420639823185362 EGAGS(ph)PAAPGTLPLEK ddPTM_PC-9_AZD4547_30min_R2 7 EGAGSPAAPGTLPLEK 16 0 O60248;O60248-2 O60248 SOX15 Protein SOX-15 1 EGAGS(0.998)PAAPGT(0.002)LPLEK;EGAGS(0.999)PAAPGT(0.001)LPLEK;EGAGS(0.999)PAAPGT(0.001)LPLEK;EGAGS(1)PAAPGTLPLEK;EGAGS(1)PAAPGTLPLEK;EGAGS(1)PAAPGTLPLEK;EGAGS(1)PAAPGTLPLEK 213.71 6.641900000000001e-22 1843209100.0 614447.0 563266.0 754251.0 968049.0 868867.0 793997.0 658891.0 782134.0 657280.0 705407.0 True False 809828.3647084465 745330.7192330273 744249.1389211512 744880.2592579592 748239.814786123 744348.242072591 717531.0225590009 661273.1619513256 692022.4789362848 680710.9156391796 1.1896802976165397 1.0949298771464102 1.0933409790003292 1.0942681278417952 1.0992034909320272 1.0934865667221696 1.0540906662048273 0.9714449214177766 1.016617279137479 1.0 19.376682718900476 -7.440067894513378 2.168902950701909 0.9949927079811152 1.1097778822687798 0.7504121552056692 0.029637811314268 0.1616822071098897 1.491948657288723 0.016185975745168467 0.009083182473490839 3.630212981634838e-08 7.440067894513378 0.11478517428766466 EGAGS(ph)PAAPGTLPLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 11 EGAGSPAAPGTLPLEK 16 0 O60248;O60248-2 O60248 SOX15 Protein SOX-15 1 EGAGS(0.999)PAAPGT(0.001)LPLEK;EGAGS(0.996)PAAPGT(0.004)LPLEK;EGAGS(0.999)PAAPGT(0.001)LPLEK;EGAGS(0.997)PAAPGT(0.003)LPLEK;EGAGS(1)PAAPGTLPLEK;EGAGS(1)PAAPGTLPLEK;EGAGS(0.799)PAAPGT(0.201)LPLEK;EGAGS(0.994)PAAPGT(0.006)LPLEK;EGAGS(0.974)PAAPGT(0.026)LPLEK;EGAGS(0.994)PAAPGT(0.006)LPLEK;EGAGS(1)PAAPGTLPLEK 218.34 3.2726e-22 1517695300.0 691770.2 788885.0 693989.0 845489.0 840218.0 751304.0 792104.6 763790.0 682849.7 572926.7 True False 808873.2317757534 867200.2892406641 710536.3297279393 798118.9924423238 675583.31445538 711904.2956448977 717070.7179473155 743741.3218023991 692835.0850377865 676793.7754247386 1.19515465588927 1.281336088968063 1.049856478484934 1.1792646762175738 0.9982114773904369 1.0518777233110996 1.059511396211202 1.0989186792323051 1.023701916588965 1.0 19.368356774270033 -5.4471837521666835 1.1905658389475697 1.0495596033917358 1.252006042956529 0.5812015083911304 0.058058277142983436 0.4395044097395382 1.0413724626113852 0.018359879053825027 0.08279995369306968 3.571217062024066e-06 5.4471837521666835 0.20244643956479313 EGAGS(ph)PAAPGTLPLEK ddPTM_PC-9_Lapatinib_30min_R1 7 EGAGSPAAPGTLPLEK 16 0 O60248;O60248-2 O60248 SOX15 Protein SOX-15 1 EGAGS(1)PAAPGTLPLEK;EGAGS(0.999)PAAPGT(0.001)LPLEK;EGAGS(0.993)PAAPGT(0.007)LPLEK;EGAGS(1)PAAPGTLPLEK;EGAGS(0.873)PAAPGT(0.127)LPLEK;EGAGS(0.994)PAAPGT(0.006)LPLEK;EGAGS(1)PAAPGTLPLEK 201.57 1.5654e-12 1579614100.0 874898.0 778183.0 829978.0 744655.0 801437.0 764782.0 754051.0 702593.0 771323.0 593250.0 True False 862421.794083356 776381.1650749221 761740.4126477292 799419.4127962607 754298.0513457656 732074.0566539173 793092.0711801203 735238.0357218501 684448.4813487281 695792.4720440637 1.2394813521764287 1.1158228872383587 1.094781049311912 1.1489336905985301 1.0840848121420847 1.0521442614969192 1.1398399710336256 1.0566915643135735 0.9836963014819492 1.0 19.408297544594028 -1.5228787452803794 0.15195766413650597 0.976320412723757 1.7733107708665017 0.6546041992816851 0.041948051011353904 46.439202840069164 0.46282961085142665 0.1485297587602751 8.179531464923572 0.029999999999997112 1.5228787452803794 0.7969903581427447 EGAKDIDIS(ph)SPEFK ddPTM_PC-9_Lapatinib_30min_R1 1 EGAKDIDISSPEFK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 EGAKDIDIS(0.5)S(0.5)PEFK 53.754 0.038678 2609800.0 145450.0 13619.0 22108.0 20825.0 12829.0 16364.0 8878.8 9785.5 19605.0 10258.0 True False 143375.8563277367 13587.466042248861 20290.365579347912 22356.53997016349 12074.423442784435 15664.149866347143 9338.500819697942 10240.170053724063 17396.87845019768 12031.081632074176 11.917121062956205 1.129363631448186 1.6864955454424777 1.8582319240991791 1.003602486628859 1.3019735336669493 0.77619794340037 0.8511429285314094 1.4459945483054988 1.0 13.55447873071531 -4.761083761116066 24.99999491672476 1.2386446862027725 11.917133018137642 0.9892290545727164 0.33460705355655934 0.8220957162388575 57714.42707786043 0.09013251554994618 0.5126164748337994 1.733469636254633e-05 4.761083761116066 10.67848833193487 EGALCEENMR ddPTM_PC-9_Lapatinib_30min_R1 2 EGALCEENMR 10 0 P13639 P13639 EEF2 Elongation factor 2 0 ; 133.99 0.00050978 19047500.0 44352.0 45358.0 52795.0 51380.0 50735.0 49440.0 38878.0 42453.0 49069.0 44197.0 False True 43719.53234683934 45252.9763377872 48454.39889459348 55158.65659865547 47750.867048847824 47325.56645026901 40890.912608485014 44425.52136229604 43542.33250052282 51836.39256119934 0.8434138678771477 0.8729962503536566 0.9347563844722993 1.0640913434231323 0.9211842238533856 0.9129795518543322 0.7888456466218822 0.8570334309017773 0.8399954230826471 1.0 15.661677700103018 -7.02261277339329 21.558081016690473 0.8583201011094296 0.9307667518717937 0.10389868961086901 0.07354487666551056 247.73176805902486 236175.60956150934 0.02873070885834138 0.022501757723014895 9.492644713730031e-08 7.02261277339329 0.07244665076236412 EGDELEDNGKNFY(ph)ESDDDQKEK ddPTM_PC-9_Lapatinib_30min_R1 2 EGDELEDNGKNFYESDDDQKEK 22 2 O00203-3;O00203 O00203-3 AP3B1 AP-3 complex subunit beta-1 1 EGDELEDNGKNFY(0.926)ES(0.074)DDDQKEK;EGDELEDNGKNFY(0.842)ES(0.158)DDDQKEK 78.708 0.00090482 16011700.0 57170.0 75311.0 52745.0 62412.0 72628.0 58438.0 65224.0 58340.0 52695.0 55235.0 True False 56354.74531630602 75136.62200659422 48408.50970158792 67001.98668032867 68356.16383214181 55938.74296563151 68600.97957651703 61050.68938064098 46759.934197050046 64782.29615398881 0.8699096614659916 1.1598326466847202 0.7472490568491108 1.0342638445704921 1.0551673511179327 0.8634881176898083 1.0589464043301449 0.9423977383500312 0.7218011242747671 1.0 15.983311983700842 -8.01968601325066 24.48287426080884 0.8513001544520884 0.9724255903200685 0.09940161790276425 0.12854587796661016 1171.2426338456169 1456626.89485912 0.07825661536624733 0.03054776334800944 9.556832773636641e-09 8.01968601325066 0.12112543586798008 EGDIIPPLTGAT(ph)PPLIGHLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EGDIIPPLTGATPPLIGHLK 20 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7C3N7 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 EGDIIPPLT(0.021)GAT(0.979)PPLIGHLK;EGDIIPPLT(0.001)GAT(0.999)PPLIGHLK 111.11 0.00012613 21616300.0 132594.0 122165.0 125597.0 126726.0 124482.0 117742.0 126300.0 90692.0 95674.0 81582.0 True False 155039.54534912598 134292.73383964185 128591.70880927522 119625.95307123537 100090.64570151412 111567.40224705517 114335.94966718533 88311.43109611713 97073.05125257454 96372.1707972434 1.6087584628067826 1.3934804283093218 1.3343240869796142 1.2412914649698554 1.038584529885645 1.1576723998651115 1.1864000646798314 0.9163582221460468 1.0072726436432125 1.0 16.556328981926548 -1.5228787471717347 0.29165460718131536 0.9683790647775489 6.2520710979792 0.8794130104512035 0.07018976805343581 17.400672215000252 0.24713454481417665 0.07725486265855447 47.50655355040334 0.029999999869346917 1.5228787471717347 5.283692033201651 EGDIIPPLTGATPPLIGHLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGDIIPPLTGATPPLIGHLK 20 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7C3N7 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 0 132.13 3.5959e-05 2560300.0 11983.0 7980.1 12062.0 10132.0 12871.0 11256.0 11303.0 8798.8 10062.0 7771.4 False True 14011.485224961772 8772.311589356399 12349.603825389744 9564.336888387204 10349.019945246584 10665.715544944478 10232.298013366535 8567.84082309921 10209.137714566194 9180.293301631453 1.5262568160509378 0.9555589675764988 1.3452297676801965 1.0418334767896253 1.1273082030404664 1.1618055321880671 1.1145938018721175 0.933286175244161 1.1120709741105879 1.0 13.164324531770623 -4.749565776812481 24.99954416848596 1.0968474311180476 1.5262577784455655 0.576452389219365 0.11247605504255091 397.003376009503 835828.1339375202 0.027051728532329955 0.4369159061836014 1.7800582866682622e-05 4.749565776812481 0.4294103473275179 EGDIVKR ddPTM_PC-9_AZD4547_30min_R2 1 EGDIVKR 7 1 P25705-2;P25705;K7EQH4;K7EJP1;K7ERX7;K7EK77;P25705-3 P25705-2 ATP5A1 ATP synthase subunit alpha, mitochondrial 0 67.035 0.033364 6754800.0 45267.0 37469.0 48737.0 76038.0 63376.0 53583.0 42021.0 50898.0 52844.0 58725.0 False True 59660.964387908425 49580.121503769566 48090.71553580988 58508.613875389274 54577.336349389974 50232.44653943981 45760.7875945365 43032.883619684704 55637.22595683582 56669.05562449889 1.052796164157641 0.8749064362797556 0.8486239095719029 1.032461424151475 0.9630888630124862 0.8864175692690308 0.8075092674520135 0.7593718149254094 0.9817920087728267 1.0 15.790273540048688 -6.875381068339026 5.041350290717612 0.8646761680449379 0.9481347758908135 0.10152116537886413 0.08945497021794904 0.40632770759296766 16.286083579543877 0.032103589941766056 0.028323208542002907 1.3323518572739195e-07 6.875381068339026 0.08345860784587567 EGDLIAAQAR ddPTM_PC-9_AZD4547_30min_R2 1 EGDLIAAQAR 10 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 93.598 0.030831 5097100.0 29380.0 28069.0 36776.0 51845.0 42061.0 35977.0 27413.0 34609.0 26595.0 33806.0 False True 38722.228858036746 37141.75533078834 36288.32621098848 39892.936247265214 36221.55617570836 33727.35250264873 29852.703893982303 29260.97428570217 28000.757405231416 32622.462229745553 1.186980571403018 1.138533169851356 1.1123723879401215 1.2228671142698222 1.1103256376117776 1.0338690030544575 0.9150965884715547 0.8969578715312807 0.8583275292966693 1.0 14.99357805530202 -6.969410447865428 1.9093736060698763 0.905755233413243 1.1596705725731307 0.8643865143347941 0.04435519562813325 0.11135135673566954 0.820909569244645 0.019339130440372804 0.015243305846854554 1.0729748739582004e-07 6.969410447865428 0.2539153391598876 EGDLIAAQAR ddPTM_PC-9_Lapatinib_30min_R1 1 EGDLIAAQAR 10 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 101.46 0.016557 7216900.0 36353.0 41522.0 43667.0 46050.0 47061.0 37020.0 31896.0 40636.0 39233.0 34204.0 False True 35834.59955367627 41425.858360104095 40076.867819494524 49436.6706182967 44292.96450548588 35436.740897834956 33547.41881167338 42524.096909011416 34814.16639819462 40116.1158260348 0.8932719136886157 1.032648787328989 0.9990216399137325 1.2323394127357912 1.1041189704796983 0.8833542372723184 0.8362579008683979 1.0600252799503054 0.8678349257233101 1.0 15.291894305793859 -6.761922898950507 24.99999993105654 0.9274187574067015 1.0582340053829522 0.27180306734628723 0.10022279733273581 18.143990416484566 938092.8932763515 0.03573112003989257 0.03345097837211951 1.7301234837624894e-07 6.761922898950507 0.13081524797625066 EGDPAIYAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGDPAIYAER 10 0 Q9UGI8-2;Q9UGI8;H7BYK1 Q9UGI8-2 TES Testin 0 102.62 0.014491999999999998 3689700.0 24847.0 24930.0 25389.0 23874.0 28939.0 27723.0 22823.0 24237.0 19815.0 18274.0 False True 29053.106349380374 27404.885643369766 25994.37004831868 22536.41718055232 23268.610690349702 26269.157076447733 20661.040215789104 23600.80443122423 20104.756888702952 21586.93154309559 1.3458654969734585 1.2695127878021646 1.204171607086639 1.0439842798204646 1.077902648826993 1.216900930269069 0.9571087106355036 1.0932912991412511 0.9313392618384108 1.0 14.397870566764912 -1.522878746485912 0.28984516277567735 0.9886771029112784 4.014600627242467 0.7085045792735812 0.0712744249528685 29.0287573582474 0.4118886633482868 0.07542007057874175 45.01022544125298 0.029999999916721875 1.522878746485912 3.025923524331188 EGDPVSLSTPLETEFGS(ph)PSELSPR ddPTM_PC-9_AZD4547_30min_R2 1 EGDPVSLSTPLETEFGSPSELSPR 24 0 E9PMR3;E9PMG4;Q9BUR4 E9PMR3 WRAP53 Telomerase Cajal body protein 1 1 EGDPVSLSTPLET(0.007)EFGS(0.809)PS(0.178)ELS(0.007)PR 91.249 6.4614e-06 1340200.0 5356.8 4203.6 6163.1 9177.4 7453.3 7769.8 6323.8 8580.4 6918.8 6427.1 True False 7060.150971638232 5562.331494121696 6081.373267101999 7061.692219416572 6418.537948322841 7283.9531777268785 6886.605949176128 7254.496337976796 7284.513642989853 6202.08918525699 1.1383504430121616 0.8968480342630246 0.9805362492300262 1.1385989476260592 1.0348993309513141 1.1744354136411954 1.1103687392219874 1.1696859108736273 1.1745257808136487 1.0 12.598538556533756 -5.760331901840137 24.99991871023631 1.1207054976120248 0.9944051981826362 0.2868426642275007 0.07808465746353009 31.59976404602603 713286.6770498612 0.02076929771562171 0.03354135488782516 1.7364732527005208e-06 5.760331901840137 -0.12630029942938859 EGDPVSLSTPLETEFGSPSELS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 EGDPVSLSTPLETEFGSPSELSPR 24 0 E9PMR3;E9PMG4;Q9BUR4 E9PMR3 WRAP53 Telomerase Cajal body protein 1 1 EGDPVSLSTPLETEFGS(0.029)PS(0.288)ELS(0.683)PR 82.50299999999999 3.764e-05 1326400.0 4760.1 3859.9 5400.0 9058.9 7230.7 4909.3 2920.2 6309.3 4697.4 4222.5 True False 6273.712783769257 5107.53719054152 5328.39247170268 6970.510563609815 6226.842115967152 4602.320694923237 3180.092142823005 5334.342658290638 4945.694974067835 4074.671560228971 1.5396855160067708 1.2534843888753844 1.3076863724945866 1.710692619166124 1.5281825845166381 1.129494887353477 0.7804536134549955 1.3091466586796217 1.2137653062250537 1.0 11.992468059950513 -6.8097792878617005 6.600017459216317 1.0838150543841631 1.4604669048033867 0.5419286101413765 0.17541737068191962 0.17560289725379266 17.662629708540724 0.06579689774399063 0.05857765920649143 1.5496039406962474e-07 6.8097792878617005 0.37665185041922356 EGDPVSLSTPLETEFGSPSELS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGDPVSLSTPLETEFGSPSELSPR 24 0 E9PMR3;E9PMG4;Q9BUR4 E9PMR3 WRAP53 Telomerase Cajal body protein 1 1 EGDPVSLSTPLET(0.002)EFGS(0.013)PS(0.238)ELS(0.748)PR 78.108 0.00011115 1377500.0 9829.7 9291.3 10561.0 10337.0 12346.0 10085.0 11282.0 9313.9 8927.1 8931.7 True False 11493.67406457537 10213.678859937483 10812.814292815532 9757.851403006174 9926.889926502561 9556.124846372159 10213.287285393368 9069.419993892778 9057.641949086046 10550.946506701706 1.0893500462043728 0.9680343705135839 1.0248193643999137 0.924831852460651 0.9408530239630388 0.9057125671428946 0.9679972577726685 0.8595835442945428 0.8584672420936691 1.0 13.365084805901216 -3.291417890724101 0.47469360855243364 0.9084400266518903 1.6995015814267949 0.5175087839890808 0.047741978870223564 13.880657605502346 0.7919644883100272 0.028199663570858794 8.342035832280578 0.000511189717267228 3.291417890724101 0.7910615547749046 EGDPVSLSTPLETEFGSPSELS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 EGDPVSLSTPLETEFGSPSELSPR 24 0 E9PMR3;E9PMG4;Q9BUR4 E9PMR3 WRAP53 Telomerase Cajal body protein 1 1 EGDPVSLST(0.001)PLET(0.195)EFGS(0.09)PS(0.105)ELS(0.607)PR;EGDPVSLSTPLET(0.003)EFGS(0.009)PS(0.235)ELS(0.752)PR 80.067 7.8388e-05 2837800.0 7939.3 7670.6 11534.9 9175.2 9091.9 7636.0 7284.7 8215.2 10135.6 7108.8 True False 7826.084126110697 7652.839196980262 10586.545048001639 9849.974815569953 8557.132317363152 7309.426080385402 7661.866121689151 8596.908183062074 8994.021995400337 8337.546608119414 0.9386555174983208 0.9178766316613621 1.2697434324015733 1.1813996704951166 1.0263369693225939 0.8766878824122207 0.9189593152292235 1.0311076611781798 1.078737237479623 1.0 13.025407205860635 -6.520970100042981 24.90143825607265 0.9760871149831974 1.082398908370915 0.1439541922026656 0.1095028724286289 143.76531902108022 1875690.92745052 0.03957867735420857 0.04015602542797974 3.013213468341239e-07 6.520970100042981 0.10631179338771746 EGDVLTLLESER ddPTM_PC-9_AZD4547_30min_R2 4 EGDVLTLLESER 12 0 P62857 P62857 RPS28 40S ribosomal protein S28 0 ;;; 225.93 9.694899999999999e-15 33587100.0 41240.9 35587.8 52910.2 69945.0 60252.0 52926.0 46245.3 62005.0 45249.0 49168.0 False True 54354.64833599074 47090.8603926406 52208.57617708943 53820.26088947756 51887.0498252248 49616.52885330033 50361.04211098305 52423.55198315359 47640.76976233564 47446.64328557444 1.145595232287309 0.9925014106731969 1.1003639575270605 1.13433231863298 1.0935873695621459 1.0457331734653106 1.0614247631358718 1.104894853522595 1.0040914691391924 1.0 15.534018403854727 -8.273345427614757 23.397550269304556 1.0020456700790725 1.0821080734305608 0.38338893574112753 0.04186996268475411 385.42241840954756 757406.8675650435 0.0385225821514215 0.010328907776356257 5.3291086211312155e-09 8.273345427614757 0.08006240335148829 EGDVLTLLESER ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 EGDVLTLLESER 12 0 P62857 P62857 RPS28 40S ribosomal protein S28 0 ;;;;; 180.19 0.00039175 23274800.0 40998.2 42232.7 54012.2 50047.299999999996 52139.8 44709.600000000006 51777.0 44140.6 47385.6 39976.9 False True 47938.385508639556 46425.283349809186 55300.0556904092 47243.31203653578 41923.38047868605 42364.94986924745 46872.30772698211 42981.95602083163 48078.52475525221 47224.39551303371 1.0151190923218654 0.9830784035551291 1.171006110076023 1.0004005667684375 0.8877483771521308 0.8970988280316881 0.9925443664820562 0.9101642393488936 1.018086610383033 1.0 15.527244709335566 -5.999984202753085 24.999999043037143 0.9456765233718247 1.055174661398096 0.37192321059996103 0.06130797987957087 0.5837193915688108 917457.7500550887 0.017234602852498972 0.02527101368352902 1.0000363751668173e-06 5.999984202753085 0.10949813802627117 EGDVLTLLESER ddPTM_PC-9_Lapatinib_30min_R1 4 EGDVLTLLESER 12 0 P62857 P62857 RPS28 40S ribosomal protein S28 0 ;;; 230.95 2.5697e-15 74790000.0 104911.0 100353.0 112208.0 103546.0 118791.0 115002.0 98842.0 90428.0 109313.0 91987.0 False True 103414.94990167902 100120.63879417015 102982.69137540588 111161.11825933034 111803.94693209173 110083.63254275553 103959.55512237965 94629.61500364429 97001.01882307876 107886.8303850272 0.9585502654273101 0.9280153883181013 0.9545436732906194 1.0303492823231328 1.0363076432321265 1.0203620974857484 0.9635981959185206 0.8771192430617297 0.8990997184447899 1.0 16.719159241970786 -10.286769144387302 5.040900746896126 1.000000020098178 0.9651215308061921 0.04369598145640352 0.0510011604739057 1.3525919118723983e-08 3.2719476025567926e-09 0.056762237444535915 0.013766856531381244 5.166909509530684e-11 10.286769144387302 -0.03487848929198589 EGEDGDQPT(ph)TPPKPLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGEDGDQPTTPPKPLK 16 1 M0R0Q7;P18858-2;P18858;P18858-3;B4E135 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 EGEDGDQPT(0.97)T(0.03)PPKPLK 203.05 2.8087999999999998e-50 0.0 25773.0 40526.0 25930.0 26438.0 27660.0 18814.0 30191.0 17006.0 18876.0 20702.0 True False 30135.85986004669 44549.15345299653 26548.26954007262 24956.76457315246 22240.221558971385 17827.36071984588 27331.089916088564 16559.610519346417 19152.025790116426 24455.108723058176 1.2322930231601164 1.8216706356734422 1.0855919652911152 1.0205133355069194 0.9094304920428171 0.7289830898619911 1.1176024701259533 0.6771431976392209 0.7831503023357409 1.0 14.577848258204632 -5.488110955134347 3.534180681649383 0.8848615824083556 1.5271596000707306 0.6410389890789625 0.18654396478523716 0.13079361689683017 3.360638671106268 0.04905185382139833 0.1048650251564677 3.2500425350854796e-06 5.488110955134347 0.642298017662375 EGEDGDQPT(ph)TPPKPLK ddPTM_PC-9_Lapatinib_30min_R1 1 EGEDGDQPTTPPKPLK 16 1 M0R0Q7;P18858-2;P18858;P18858-3;B4E135 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 EGEDGDQPT(0.5)T(0.5)PPKPLK 67.645 0.017744 56138000.0 248170.0 364250.0 257730.0 345150.0 411920.0 380860.0 364880.0 384260.0 305870.0 321870.0 True False 244631.05029119606 363406.60150445416 236540.43426656982 370533.48238664743 387691.6754658793 364571.5056280229 383771.7010284483 402114.12241009704 271419.6996461087 377504.8006351841 0.6480210314665759 0.9626542520598188 0.6265892085837592 0.9815331666330949 1.0269847557264302 0.9657400515559011 1.016600849532826 1.0651894273490181 0.7189834385931566 1.0 18.526135465387206 -5.788215043679693 24.989990879965806 0.9749838389922498 0.76744477607585 0.40264418497133136 0.12291157895905226 209.55952369225358 195583.15437861567 0.03283307861777511 0.048714414569575835 1.6284894760308855e-06 5.788215043679693 -0.20753906291639979 EGEEAGPGDPLLEAVPK ddPTM_PC-9_Lapatinib_30min_R1 1 EGEEAGPGDPLLEAVPK 17 0 Q16543;K7EL68 Q16543 CDC37 Hsp90 co-chaperone Cdc37;Hsp90 co-chaperone Cdc37, N-terminally processed 0 146.67 0.00040808 2312800.0 21032.0 20797.0 21821.0 20237.0 19636.0 16863.0 20559.0 16822.0 18039.0 18479.0 False True 20732.079823203574 20748.845824263874 20026.961611495877 21725.296488653 18481.049085861345 16141.80879957296 21623.444424040412 17603.611531730246 16007.257860908745 21673.070528280263 0.9565824923677136 0.9573560791577544 0.9240481908349605 1.0024097167175545 0.8527194640808378 0.7447864287854462 0.9977102411873252 0.8122343121045099 0.7385782203782135 1.0 14.403615941015643 -6.279706449759658 22.86240617625693 0.849640818330738 0.9573281050571378 0.25482216408205927 0.08509463504908162 362.1605325363898 453265.22587619704 0.02584782834470771 0.029387158607712474 5.251623103337769e-07 6.279706449759658 0.10768728672639982 EGEEPTVYS(ph)DEEEPK ddPTM_PC-9_Lapatinib_30min_R1 2 EGEEPTVYSDEEEPK 15 0 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 EGEEPT(0.002)VYS(0.997)DEEEPK;EGEEPTVYS(1)DEEEPK 231.17 2.3589999999999998e-92 8118400.0 49664.0 78521.0 21746.0 17584.3 27126.0 23997.0 38912.0 32877.0 30290.0 16481.6 True False 48955.78225273781 78339.18944881584 19958.127821987506 18877.5080815052 25530.502011767912 22970.704249739207 40926.67296212173 34404.58544338933 26878.421232159515 19330.422599648446 2.532576926364152 4.052637186019957 1.032472400388726 0.9765698594633164 1.3207420520766175 1.1883187825473078 2.117215635154611 1.779815483393262 1.3904725100344335 1.0 14.23858555748932 -5.26896720249016 24.999065153548074 1.3856957478661658 3.2926070877784492 0.721097500517549 0.4826858049075899 263.0133361020171 873440.1254826162 0.1273684341931536 0.2735820556494638 5.383104336777571e-06 5.26896720249016 1.9069113399122835 EGEEPTVYS(ph)DEEEPKDESAR ddPTM_PC-9_AZD4547_30min_R2 3 EGEEPTVYSDEEEPKDESAR 20 1 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 EGEEPT(0.002)VY(0.005)S(0.993)DEEEPKDESAR;EGEEPT(0.05)VY(0.009)S(0.941)DEEEPKDESAR;EGEEPTVYS(1)DEEEPKDESAR 138.04 6.3951e-06 1469459000.0 128440.0 168787.0 138073.0 92394.0 96297.0 91588.0 162666.0 118789.0 132180.0 101402.0 True False 169281.24828203698 223344.09694031757 136242.06180470434 71093.99077307018 82927.82375721436 85860.98788149634 177142.9588742028 100432.88954966253 139166.76494918164 97851.94684436689 1.7299732273214563 2.2824696303237118 1.392328575959728 0.7265465130310067 0.847482614618907 0.8774581462140747 1.8103161417518645 1.0263759974995759 1.4222176403963203 1.0 16.5783129342827 -5.445062360516481 5.090486791178933 1.1079290483659148 1.9911605187066563 0.5520287738612495 0.32166526646888627 0.16127342684042076 7.378411680356546 0.08824347593473401 0.18680662209375834 3.58870400602391e-06 5.445062360516481 0.8832314703407416 EGEEPTVYS(ph)DEEEPKDESAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EGEEPTVYSDEEEPKDESAR 20 1 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 EGEEPT(0.013)VYS(0.987)DEEEPKDESAR;EGEEPT(0.021)VYS(0.979)DEEEPKDESAR 134.83 2.4101999999999997e-05 962204000.0 168368.0 229815.0 138684.0 133823.0 213346.0 98875.0 186808.0 105171.0 111070.0 108204.0 True False 196869.37698041927 252629.51440557698 141990.75252199866 126325.33117001949 171542.3828170757 93689.82094051034 169112.1938672014 102410.37268788561 112694.18862620436 127820.52865760702 1.540201554851752 1.9764392860734907 1.1108603133879178 0.9883023681462567 1.3420565899597119 0.7329794511449516 1.3230440809723327 0.8012044212570297 0.8816595409965671 1.0 16.9637600338368 -5.3424129244697935 5.769707884596672 1.0209647194897846 1.7549077789121998 0.6611176564917438 0.21117719695527745 0.11386118841220565 6.246479275376943 0.052893735805523784 0.11308393931436057 4.545556659472562e-06 5.3424129244697935 0.7339430594224152 EGEEPTVYS(ph)DEEEPKDESAR ddPTM_PC-9_Lapatinib_30min_R1 4 EGEEPTVYSDEEEPKDESAR 20 1 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 EGEEPTVY(0.001)S(0.999)DEEEPKDESAR;EGEEPTVYS(1)DEEEPKDESAR;EGEEPT(0.151)VY(0.012)S(0.837)DEEEPKDESAR;EGEEPTVYS(1)DEEEPKDESAR 171.9 5.1922e-09 1929760000.0 245155.0 447075.0 151116.0 109576.0 147358.0 172831.0 205298.0 170835.0 222062.0 80283.5 True False 241659.0447440793 446039.8253057067 138691.825804629 117634.58457482033 138690.69215697487 165439.42101873862 215927.32590917128 178772.61776382884 197051.03914347326 94160.39600396054 2.566461644170599 4.737021552956781 1.4729316325177244 1.2493000196162347 1.472919592979848 1.756995807576892 2.293186255292395 1.8985967067970844 2.0927167631621364 1.0 16.52283276738278 -5.277995580183085 24.90176475367355 1.6921762980333572 3.651741628009526 0.6328734874806398 0.6079072372743977 402.1763799112553 604903.1565364144 0.15338112401831552 0.3207494157017518 5.272352270708199e-06 5.277995580183085 1.9595653299761688 EGEEPTVYS(ph)DEEEPKDESARK ddPTM_PC-9_Lapatinib_30min_R1 1 EGEEPTVYSDEEEPKDESARK 21 2 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 EGEEPT(0.13)VY(0.178)S(0.692)DEEEPKDESARK 72.676 0.0057042 13924000.0 46815.0 64514.0 16619.0 17953.0 17786.0 22714.0 24639.0 18626.0 22572.0 10742.0 True False 46147.40951518045 64364.621796728345 15252.64997119518 19273.323509452348 16739.862448621407 21742.575168920128 25914.686860447113 19491.431957556033 20029.703666302572 12598.740387184718 3.66285899200852 5.108814041616354 1.2106488031700364 1.5297817811260666 1.328693340300034 1.7257737282241647 2.0569268088742594 1.547093706080528 1.5898179540771027 1.0 13.620991880893527 -5.266262776394809 24.999999973348356 1.5412312864826399 4.385836606519871 0.8812521604054535 0.42371063271217807 104.17186652121264 539932.5870659193 0.10485510698530373 0.23000347008387115 5.416730438219849e-06 5.266262776394809 2.844605320037231 EGEFVAQFK ddPTM_PC-9_Lapatinib_30min_R1 2 EGEFVAQFK 9 0 Q9UQ80;Q9UQ80-2 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 0 ; 108.98 0.011056 7133200.0 61480.0 60936.0 69788.0 52690.0 57575.0 52268.0 59540.0 55527.0 55086.0 60930.0 False True 60603.2839259488 60794.90643589668 64050.300029470476 56564.99836868738 54188.5516968052 50032.61948265903 62622.68986854254 58106.987131279595 48881.63459870385 71461.66931587827 0.8480530122808534 0.8507344849050215 0.8962888866526794 0.7915431994550265 0.7582883553598277 0.7001322521798709 0.8763116012828464 0.8131210435965653 0.6840259269991991 1.0 16.124881994642664 -5.778643441303998 24.280482528350497 0.792421657988456 0.8635963546535815 0.08866786046192932 0.08571079652673354 341.61887006781785 482133.2560736958 0.023161662896768246 0.03445842371504056 1.6647788841313341e-06 5.778643441303998 0.07117469666512555 EGES(ph)LEDLMK ddPTM_PC-9_AZD4547_30min_R2 2 EGESLEDLMK 10 0 P13796 P13796 LCP1 Plastin-2 1 EGES(1)LEDLMK;EGES(1)LEDLMK 99.539 0.0038171 21711300.0 220125.0 267367.0 214468.0 147596.0 190250.0 258241.0 300570.0 266193.0 286810.0 208412.0 True False 290120.1711155663 353788.1541033487 211624.01418909835 113570.02253546842 163837.07145404312 242093.14944649357 327320.14771875605 225058.98835660995 301970.19106578035 201115.55931567564 1.4425545795797279 1.7591287084259581 1.0522508298670636 0.5647003291138021 0.8146414529612831 1.2037514664218423 1.6275227477799805 1.1190530912794874 1.5014760274803052 1.0 17.61766517457447 -5.268953324039741 24.708923437994564 1.106423447824989 1.6008416482016021 0.3041237257887409 0.29668404377015445 584.4550914262792 1921933.2250205965 0.08610341406631149 0.1850902978858797 5.38327636369359e-06 5.268953324039741 0.4944182003766131 EGES(ph)LEDLMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EGESLEDLMK 10 0 P13796 P13796 LCP1 Plastin-2 1 EGES(1)LEDLMK;EGES(1)LEDLMK 86.463 0.009906700000000001 14368500.0 112204.0 169946.0 100512.0 115194.0 127697.0 73148.0 117270.0 83779.0 77027.0 84367.0 True False 131197.92106998336 186817.11574601394 102908.58727388261 108740.05364398705 102675.68953058464 69311.99011030544 106161.33663872343 81579.89002118821 78153.37415423266 99662.06925119557 1.3164278251066865 1.8745056885699052 1.032575262053854 1.0910876571297217 1.0302383876035457 0.6954701084482445 1.0652130488194724 0.8185650833274221 0.7841837395253071 1.0 16.604756908090728 -5.388551988337708 5.381120919945938 0.929398350715221 1.5904035842212383 0.6939032528687279 0.175085761845291 0.11196319416246267 4.3832437414291245 0.045144453472674886 0.09635416363301125 4.087408198115165e-06 5.388551988337708 0.6610052335060173 EGES(ph)LEDLMK ddPTM_PC-9_Lapatinib_30min_R1 3 EGESLEDLMK 10 0 P13796 P13796 LCP1 Plastin-2 1 EGES(1)LEDLMK;EGES(1)LEDLMK;EGES(1)LEDLMK 89.301 0.0092291 17977900.0 92372.9 224628.0 144273.1 177090.8 214329.5 201745.1 214096.1 242941.2 169083.2 198715.2 True False 91055.64550688458 224107.8876671035 132411.5226282715 190114.64818959066 201723.06019800986 193116.93236379788 225180.9484777372 254229.13505245355 150039.2694909698 233062.85754863947 0.3906913631138396 0.9615770184244519 0.568136527720371 0.8157226346111985 0.8655307084094723 0.828604499211098 0.9661811875396862 1.0908178923336025 0.6437716891875708 1.0 17.83035957971866 -4.060643937523016 0.42901994511628233 0.9310808225458005 5.0392809059220425e-14 0.3612002991382205 0.16528096142724147 11.386099240499881 1.021760206410688 0.11432133399920394 6.133688411438316 8.69673150919035e-05 4.060643937523016 -0.9310808225457501 EGETQGVAFEHESPADFQNS(ph)QSPVQDQDK ddPTM_PC-9_AZD4547_30min_R2 2 EGETQGVAFEHESPADFQNSQSPVQDQDK 29 0 E9PGM9;P78332;F8WCA5;P78332-3 E9PGM9 RBM6 RNA-binding protein 6 1 EGETQGVAFEHESPADFQNS(0.5)QS(0.5)PVQDQDK;EGETQGVAFEHESPADFQNS(0.613)QS(0.387)PVQDQDK 154.17 4.8712e-12 13182700.0 10914.7 10025.0 49758.0 76131.0 65282.0 73092.0 31737.0 78108.0 50957.0 62549.0 True False 14385.34756013662 13265.385200440096 49098.176408700354 58580.17416222493 56218.72114934486 68521.54568539886 34561.53151728434 66038.2033432814 53650.482989222655 60359.17854843384 0.23832908111221937 0.2197741175320269 0.8134334758930267 0.9705263651860109 0.9314030194137489 1.135229924151723 0.5725977779759085 1.0940871783119208 0.8888537630804908 1.0 15.881285551349018 -5.314772766026817 3.6119586766458647 0.9355142495345972 0.2142376344941837 0.7919180782791256 0.14391053095127682 0.09106733404608898 2.406943140961442 0.03708228581786186 0.09176064196821551 4.844257652281945e-06 5.314772766026817 -0.7212766150404135 down EGETQGVAFEHESPADFQNS(ph)QSPVQDQDKSQLSGR ddPTM_PC-9_AZD4547_30min_R2 2 EGETQGVAFEHESPADFQNSQSPVQDQDKSQLSGR 35 1 E9PGM9;P78332;F8WCA5;P78332-3 E9PGM9 RBM6 RNA-binding protein 6 1 EGETQGVAFEHES(0.001)PADFQNS(0.499)QS(0.499)PVQDQDKSQLSGR;EGETQGVAFEHES(0.001)PADFQNS(0.499)QS(0.499)PVQDQDKS(0.001)QLSGR 83.479 8.8041e-10 13744400.0 8753.5 5648.6 44561.0 114965.0 72321.0 60934.0 28850.0 67586.0 30544.0 62073.0 True False 11536.9309158892 7474.399485606578 43970.09202435984 88461.59544154396 62280.4775013291 57123.78734737182 31417.594110144422 57142.13667177514 32158.49348318813 59899.84316355073 0.19260369153870277 0.12478162029904574 0.7340602195619069 1.4768251596253454 1.0397435821539345 0.9536550403212383 0.5245021097027203 0.9539613737510808 0.5368710798688149 1.0 15.870264605143413 -5.342986838832573 4.30330687375232 0.9246239805187033 0.1559876190470921 0.5834075306320148 0.25458330169360305 0.15194586278742545 5.1284889267321265 0.07171404354574712 0.16190206092310655 4.539553734267567e-06 5.342986838832573 -0.7686363614716112 EGFES(ph)DTDSEFTFK ddPTM_PC-9_AZD4547_30min_R2 2 EGFESDTDSEFTFK 14 0 E9PMS6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 EGFES(0.447)DT(0.447)DS(0.106)EFTFK;EGFES(1)DTDSEFTFK 152.11 2.0095999999999997e-08 3207000.0 22133.7 26141.0 31019.0 34413.0 30993.0 32983.0 30747.0 34779.0 32098.0 31908.0 True False 29171.75619044004 34590.56703488323 30607.667792545435 26479.614525549965 26690.156928121745 30920.56779594917 33483.42343516847 29404.704691913525 33794.634750634235 30790.910632039333 0.9474145321342172 1.1234018846746994 0.9940488009047961 0.859981532926692 0.8668193431197008 1.0042108908521505 1.0874450527074524 0.9549800278175794 1.0975522989394602 1.0 14.91021691484059 -6.993189827650981 24.921986751550946 1.0333263037381766 0.9611730362955707 0.1770843945451932 0.07812378016515108 340.3776780194002 1245611.3786085488 0.029971895617873473 0.02637578785984357 1.0158045934037057e-07 6.993189827650981 -0.07215326744260586 EGFES(ph)DTDSEFTFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EGFESDTDSEFTFK 14 0 E9PMS6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 EGFES(0.986)DT(0.013)DSEFTFK;EGFES(0.54)DT(0.414)DS(0.046)EFTFK;EGFES(0.974)DT(0.02)DS(0.006)EFT(0.001)FK 137.68 2.2944000000000003e-05 2455400.0 19228.9 22781.5 24118.7 22833.8 24919.7 18625.8 23001.6 20347.8 13918.800000000001 16723.9 True False 22483.97298191333 25043.096762311623 24693.781278679096 21554.49621417842 20036.86367256325 17649.030259153056 20822.721930837095 19813.69181027621 14122.336118217445 19755.810683680436 1.1380941709715073 1.2676319470402104 1.249950289262376 1.0910458983079754 1.014226345523496 0.8933589485007712 1.054004933750352 1.0029298279641639 0.7148446775653402 1.0 14.269989428362042 -6.134811409177216 1.8951193784377292 0.941646025722974 1.2240600208397385 0.6349625402776001 0.09342786314599634 0.22188564374529252 1.5747985510786837 0.03150815946214997 0.045554809082179 7.331428286712151e-07 6.134811409177216 0.28241399511676457 EGFES(ph)DTDSEFTFK ddPTM_PC-9_Lapatinib_30min_R1 1 EGFESDTDSEFTFK 14 0 E9PMS6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 EGFES(0.998)DT(0.002)DSEFTFK 76.01 0.016808 3140100.0 14765.0 19469.0 16760.0 22231.0 27652.0 19076.0 18688.0 19829.0 17728.0 18076.0 True False 14554.448392430615 19423.92072667179 15382.05749547091 23865.941900441994 26025.563725923705 18260.16394832791 19655.573198913735 20750.327729323428 15731.28595588393 21200.412515244 0.6865172261136592 0.9162048480285543 0.7255546317511773 1.1257300716805094 1.227597043558007 0.8613117284957581 0.927131638819789 0.9787699986688022 0.7420273518061248 1.0 14.371804716408997 -5.74636729879029 24.97796095884443 0.9826047631921085 0.7901034735073141 0.31719664655302837 0.13685336695872546 322.3825730049441 534258.8705444187 0.03890353053806679 0.0670455746556568 1.7932163963823265e-06 5.74636729879029 -0.1925012896847944 EGFGLSENPFAS(ph)LSPDEQKDEK ddPTM_PC-9_AZD4547_30min_R2 1 EGFGLSENPFASLSPDEQKDEK 22 1 B4DT96;C9JYA1;O15504-2;O15504 B4DT96 NUPL2 Nucleoporin-like protein 2 1 EGFGLSENPFAS(0.747)LS(0.253)PDEQKDEK 55.575 0.006111999999999999 5784700.0 25691.0 22926.0 34195.0 59233.0 44816.0 37633.0 30706.0 41950.0 29430.0 43160.0 True False 33860.20359400349 30336.38115763486 33741.55195738391 45577.74699072741 38594.07198046991 35279.802560863296 33438.77451459601 35467.591415100265 30985.609717464195 41648.9815368816 0.8129899542445983 0.7283823046374125 0.8101411057916174 1.0943304087848285 0.9266510381842961 0.8470747965258604 0.8028713615718269 0.8515836427762945 0.7439704063357558 1.0 15.345993596637145 -12.069439550565573 2.260656784967807 3.573483729768199 0.8504417612686088 0.17876946380335768 0.09840048670046489 8730534.77846659 592577.9921107222 117317519.72372241 0.028618823956618206 8.522371259811511e-13 12.069439550565573 -2.72304196849959 EGFGLSENPFAS(ph)LSPDEQKDEK ddPTM_PC-9_Lapatinib_30min_R1 2 EGFGLSENPFASLSPDEQKDEK 22 1 B4DT96;C9JYA1;O15504-2;O15504 B4DT96 NUPL2 Nucleoporin-like protein 2 1 EGFGLSENPFAS(0.5)LS(0.5)PDEQKDEK;EGFGLSENPFAS(0.588)LS(0.412)PDEQKDEK 82.62700000000001 0.00015774 9416400.0 33306.0 28024.0 38421.0 28792.0 37127.0 34607.0 29340.0 29326.0 34487.0 28651.0 True False 32831.05033242765 27959.112149789424 35262.173689348914 30909.45972729639 34943.26285449043 33126.939282857194 30859.081638277454 30688.593019826487 30602.71089579022 33603.287174942234 0.9770190089292682 0.8320350328892336 1.0493667927715031 0.9198344068655696 1.0398763273536944 0.985824366241162 0.9183352056488355 0.9132616359839576 0.910705870424798 1.0 15.036314748238683 -10.579759797008071 14.73920881722436 0.9999999999999404 0.9499208737964097 0.055806207454798584 0.062198457971587504 0.0 0.0 0.05946138901933257 0.014421505151332373 2.6317231634891658e-11 10.579759797008071 -0.05007912620353072 EGFGLSENPFASLS(ph)PDEQKDEK ddPTM_PC-9_AZD4547_30min_R2 1 EGFGLSENPFASLSPDEQKDEK 22 1 B4DT96;C9JYA1;O15504-2;O15504 B4DT96 NUPL2 Nucleoporin-like protein 2 1 EGFGLS(0.008)ENPFAS(0.22)LS(0.772)PDEQKDEK 49.141000000000005 0.020672 4948300.0 11904.0 7499.2 11515.0 25569.0 16354.0 13750.0 14525.0 16714.0 10769.0 16603.0 True False 15689.224381418288 9923.169745151154 11362.303576232664 19674.462087112053 14083.529390588297 12890.210326359062 15817.69686134655 14131.235349510984 11338.227354650771 16021.734023559891 0.9792463386514437 0.6193567893811728 0.709180639219478 1.2279858134070158 0.8790265379439284 0.8045452700315747 0.9872649763182122 0.8820041157050206 0.7076779166336151 1.0 13.96774267784593 EGFGLSENPFASLS(ph)PDEQKDEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGFGLSENPFASLSPDEQKDEK 22 1 B4DT96;C9JYA1;O15504-2;O15504 B4DT96 NUPL2 Nucleoporin-like protein 2 1 EGFGLSENPFAS(0.104)LS(0.896)PDEQKDEK 75.82 0.00040043 4853600.0 25832.0 22379.0 20313.0 24810.0 26515.0 23316.0 23557.0 25901.0 22428.0 20432.0 True False 30204.847394743578 24600.63922234144 20797.338957481483 23419.976135105262 21319.57608952012 22093.267914527838 21325.510422089308 25221.126194377946 22755.967070392624 24136.159860376985 1.251435504631755 1.019244128504757 0.8616672692669449 0.9703273540855418 0.883304395266262 0.9153596944308091 0.8835502642281647 1.0449519037111654 0.9428163884408908 1.0 14.558908536541521 -4.809591241201323 3.1755828910252983 0.9357510047274764 1.2875675145681367 0.7531466610902223 0.05398726185569507 0.14933343381422406 2.3627084121629838 0.013649371790681103 0.12748899339340114 1.5502750543158864e-05 4.809591241201323 0.35181650984066026 EGGGVHAVPPDPEDEGLEETGSKDKDQPPS(ph)PSPPPQSEALSSTSR ddPTM_PC-9_AZD4547_30min_R2 1 EGGGVHAVPPDPEDEGLEETGSKDKDQPPSPSPPPQSEALSSTSR 45 2 H3BU99;H3BPL8;H3BR21;H3BUX9;Q7L1V2 H3BU99 MON1B Vacuolar fusion protein MON1 homolog B 1 EGGGVHAVPPDPEDEGLEET(0.157)GS(0.157)KDKDQPPS(0.61)PS(0.073)PPPQS(0.001)EALS(0.001)S(0.001)T(0.001)S(0.001)R 56.54 3.2359e-06 8984800.0 9890.6 11316.0 12611.0 17081.0 14603.0 14446.0 9778.0 13987.0 13543.0 13798.0 True False 13035.605062739893 14973.675703559107 12443.769900118987 13143.239348819317 12575.62551612823 13542.6893363333 10648.223057504056 11825.630539285048 14258.855331417524 13314.936219784346 0.9790212170427522 1.1245773510585864 0.9345722498940014 0.9871049422895539 0.9444750848631485 1.017105085055574 0.799720170020951 0.8881477420608014 1.0708917486386929 1.0 13.700757897424209 -5.284073704412453 24.792858813865244 0.9486644257800048 1.051799295598632 0.19433070517473539 0.07771277632393328 928.9387838257862 1017526.3165467327 0.020351467960734223 0.04242308917049953 5.199077551465826e-06 5.284073704412453 0.10313486981862718 EGGGVHAVPPDPEDEGLEETGSKDKDQPPS(ph)PSPPPQSEALSSTSR ddPTM_PC-9_Lapatinib_30min_R1 1 EGGGVHAVPPDPEDEGLEETGSKDKDQPPSPSPPPQSEALSSTSR 45 2 H3BU99;H3BPL8;H3BR21;H3BUX9;Q7L1V2 H3BU99 MON1B Vacuolar fusion protein MON1 homolog B 1 EGGGVHAVPPDPEDEGLEET(0.011)GS(0.011)KDKDQPPS(0.939)PS(0.039)PPPQSEALSSTSR 70.492 1.4960999999999998e-09 7142400.0 54523.0 43149.0 41163.0 42420.0 43288.0 43009.0 42413.0 39790.0 43446.0 28008.0 True False 53745.49202170635 43049.09114156667 37778.737033774996 45539.70830897168 40741.88494748249 41169.60532887584 44608.9376115972 41638.78866053656 38552.65397333783 32849.14548168588 1.6361305974205824 1.3105087060960987 1.1500675734422823 1.386328552575624 1.2402722917159894 1.2532930377695455 1.3579938521222008 1.2675760069238664 1.1736273016548262 1.0 15.003568221166498 -1.522878745280355 0.030636409829344995 1.0441171661931435e-13 3.148073664291968 0.5173736752092625 0.11074814674015676 1250.2987405626927 2.9470440188274747 95.70787865957699 235.9790408539551 0.0299999999999988 1.522878745280355 3.148073664291864 EGGPLPNCFT(ph)TPLRQAWT(ph)T(ph)MEKSSVK ddPTM_PC-9_AZD4547_30min_R2 1 EGGPLPNCFTTPLRQAWTTMEKSSVK 26 2 E7EMD6 E7EMD6 AKAP10 3 EGGPLPNCFT(0.514)T(0.514)PLRQAWT(0.833)T(0.833)MEKS(0.153)S(0.153)VK 43.888000000000005 0.018236000000000002 9207100.0 0.0 0.0 31335.0 53722.0 32956.0 19595.0 4423.9 39532.0 12533.0 15367.0 True False 0.0 0.0 30919.47742607473 41337.22289662617 28380.62826196821 18369.721552364063 4817.618529770118 33423.23775498795 13195.468793373393 14829.006007350767 0.0 0.0 2.085067428710184 2.7875922955412675 1.9138591115210202 1.2387695805948258 0.3248780482914374 2.2539095161482834 0.8898417592407997 1.0 13.856134276308525 -5.250491373514912 24.32539493140406 1.6071700568548097 4.499413280929827e-07 0.4475207184017215 0.6926268907716678 465.95007807260487 1035287.578459254 0.18733006821378462 0.4847369943101363 5.617054355212075e-06 5.250491373514912 -1.6071696069134815 EGHALGGGMEADGPASLQELPPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 EGHALGGGMEADGPASLQELPPSPR 25 0 Q6ZVX7 Q6ZVX7 NCCRP1 F-box only protein 50 1 EGHALGGGMEADGPAS(0.004)LQELPPS(0.996)PR;EGHALGGGMEADGPAS(0.326)LQELPPS(0.674)PR;EGHALGGGMEADGPAS(0.007)LQELPPS(0.993)PR;EGHALGGGMEADGPASLQELPPS(1)PR 177.44 7.145299999999998e-46 46996900.0 75615.5 93084.5 104978.0 114773.6 110152.6 119596.4 101175.9 129076.7 116715.1 108132.9 True False 99659.65609989392 123172.24425839062 103585.92312859319 88314.31975444338 94859.81286227918 112118.01820184491 110180.35909631048 109130.86190249026 122884.42190740068 104347.2000840933 0.9550774339855627 1.1804077556381602 0.9927043854086491 0.8463506417351971 0.909078660336183 1.0744707870598265 1.0559014425640194 1.045843700784897 1.1776494415601784 1.0 16.671032364067408 -6.798583601456008 24.3433417146559 1.0727089649010675 0.9816844059069798 0.21293204217661954 0.09011859169059637 237.91713610490896 155922.61724011166 0.03445561886325383 0.03038796233100455 1.590070566624167e-07 6.798583601456008 -0.09102455899408768 EGHALGGGMEADGPASLQELPPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 EGHALGGGMEADGPASLQELPPSPR 25 0 Q6ZVX7 Q6ZVX7 NCCRP1 F-box only protein 50 1 EGHALGGGMEADGPAS(0.213)LQELPPS(0.787)PR;EGHALGGGMEADGPAS(0.014)LQELPPS(0.986)PR;EGHALGGGMEADGPASLQELPPS(1)PR;EGHALGGGMEADGPAS(0.011)LQELPPS(0.989)PR;EGHALGGGMEADGPAS(0.06)LQELPPS(0.94)PR 187.69 4.5793e-21 54434400.0 163091.7 189107.6 221259.1 211940.7 240150.1 205357.8 208421.1 166659.5 169526.7 162657.0 True False 190699.90360209407 207880.95275941078 226534.75607380935 200066.34970002077 193094.41183691766 194588.47545625415 188677.94456990765 162284.86471533644 172005.70727449338 192145.42650789648 0.9924769330601632 1.081893837066518 1.1789755301019333 1.0412235843240265 1.0049388910590706 1.0127145828696436 0.9819538669173251 0.8445939498261601 0.8951850189753258 1.0 17.551839111868482 -7.006376539219377 1.1508485651164886 0.9078319718193226 1.0782707621719778 0.5214651062515995 0.06031771631933719 0.3677143705154691 0.9984511011129594 0.03704416889410986 0.026472074605133143 9.854247385024457e-08 7.006376539219377 0.1704387903526552 EGHALGGGMEADGPASLQELPPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 6 EGHALGGGMEADGPASLQELPPSPR 25 0 Q6ZVX7 Q6ZVX7 NCCRP1 F-box only protein 50 1 EGHALGGGMEADGPAS(0.002)LQELPPS(0.998)PR;EGHALGGGMEADGPASLQELPPS(1)PR;EGHALGGGMEADGPASLQELPPS(1)PR;EGHALGGGMEADGPASLQELPPS(1)PR;EGHALGGGMEADGPAS(0.001)LQELPPS(0.999)PR;EGHALGGGMEADGPAS(0.001)LQELPPS(0.999)PR 171.56 5.294e-13 34500300.0 89296.40000000001 78243.4 88518.8 83042.7 93205.8 83492.6 83319.6 87206.09999999999 91195.0 63614.9 True False 88023.01696104587 78062.23221456018 81241.12595644922 89149.93718032654 87723.61809365332 79921.81612875681 87633.48120206609 91258.0137675199 80923.65877407683 74610.65070347395 1.1797647672431764 1.0462612439181624 1.0888676776098207 1.1948687799900883 1.1757519505129959 1.0711850838346268 1.1745438536697521 1.2231231453831943 1.0846126928405 1.0 16.187093970087606 -4.444562038134358 22.284360556184538 1.1274120423474105 4.092971895124186 0.0521536756059674 0.06896911297341297 1671.8797511091313 482218.5969891278 0.01646896793383182 3413.6905050196115 3.5928407004872424e-05 4.444562038134358 2.9655598527767753 EGHILK ddPTM_PC-9_AZD4547_30min_R2 1 EGHILK 6 0 P98174 P98174 FGD1 FYVE, RhoGEF and PH domain-containing protein 1 0 69.39 0.041227 0.0 47470.0 37095.0 49890.0 51159.0 61294.0 53841.0 46847.0 47257.0 62460.0 60151.0 False True 62564.47256266184 49085.23331773821 49228.42600245306 39365.08294867087 52784.38611145403 50474.31375865442 51016.2922453357 39954.51650782824 65761.50808538278 58045.13179853944 1.0778590835112225 0.8456391052414376 0.8481060250377753 0.6781806109993429 0.9093680120265006 0.8695701464480864 0.8789073375248913 0.6883353568133959 1.1329375271922029 1.0 15.824887453968152 -8.277070199563417 24.995345763371386 1.0664687880933823 0.8472556051031348 0.38312073748193654 0.11009870287898482 948.0589846094157 1516032.275720745 0.10255060842647234 0.026844635151458515 5.283598405403768e-09 8.277070199563417 -0.2192131829902475 EGHLS(ph)PDIVAEQK ddPTM_PC-9_AZD4547_30min_R2 2 EGHLSPDIVAEQK 13 0 B4DLR8;P15559-3;P15559-2;P15559;H3BRK3;H3BNV2 B4DLR8 NQO1 NAD(P)H dehydrogenase [quinone] 1 1 EGHLS(1)PDIVAEQK;EGHLS(1)PDIVAEQK 159.18 0.00026202 10736300.0 53218.0 47929.0 57718.0 72261.0 70718.0 59717.0 53474.0 62378.0 52996.0 61102.0 True False 70140.21699683458 63421.111947321006 56952.62160772872 55602.34287132086 60900.02638153497 55982.88654975885 58233.0824071356 52738.91340384088 55797.26036652171 58962.837578001374 1.1895665113478768 1.0756115979564556 0.9659070687089413 0.9430065640542665 1.0328544025882558 0.949460522073749 0.9876234726678411 0.8944432725794969 0.946312332623206 1.0 15.847518335142597 -4.941057067336792 1.9959467744429724 0.9619750423701828 1.2184597443973106 0.8013460318198169 0.0356150796779978 0.2233929152901435 1.2618705350887833 0.009971574203054877 0.09444355313511953 1.1453624281860693e-05 4.941057067336792 0.2564847020271278 EGHLS(ph)PDIVAEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EGHLSPDIVAEQK 13 0 B4DLR8;P15559-3;P15559-2;P15559;H3BRK3;H3BNV2 B4DLR8 NQO1 NAD(P)H dehydrogenase [quinone] 1 1 EGHLS(1)PDIVAEQK;EGHLS(1)PDIVAEQK;EGHLS(1)PDIVAEQK 92.633 0.0025621 18820600.0 140934.0 156845.0 159357.0 192948.0 188913.0 182228.0 180303.0 160682.0 145288.0 144197.0 True False 164791.34262661793 172415.53504750598 163156.67524478774 182137.7491058557 151896.8537733178 172671.64288594003 163223.39455932283 156464.26775665215 147412.5621421083 170338.774637176 0.9674329463601334 1.0121919417041336 0.9578363798396095 1.0692676960592895 0.8917338644525314 1.013695462197219 0.9582280658469629 0.9185475713907374 0.8654081400790816 1.0 17.378047351082188 -7.6017101378164575 3.7845817457044357 0.9193466149992495 0.9850651647269962 0.185897446515066 0.05279710834344751 0.3292037489678085 9.254925329942282 0.025415916388384287 0.013946408536649404 2.5020147300923756e-08 7.6017101378164575 0.06571854972774671 EGHLS(ph)PDIVAEQK ddPTM_PC-9_Lapatinib_30min_R1 2 EGHLSPDIVAEQK 13 0 B4DLR8;P15559-3;P15559-2;P15559;H3BRK3;H3BNV2 B4DLR8 NQO1 NAD(P)H dehydrogenase [quinone] 1 1 EGHLS(1)PDIVAEQK;EGHLS(1)PDIVAEQK 193.98 1.3594e-06 13625100.0 93525.0 74757.0 90131.0 81327.0 89316.0 83282.0 83637.0 84427.0 88688.0 73144.0 True False 92191.31634961537 74583.90475955629 82720.77709572112 87308.05887891895 84062.60848201215 79720.22299982415 87967.31462101605 88349.78663591642 78699.02351395723 85786.84294174623 1.0746556603349784 0.8694095994440858 0.9642594861766025 1.017732508680914 0.9799009451728521 0.9292826296680292 1.025417320471281 1.0298757199389021 0.9173787123440129 1.0 16.38846877927638 -7.277065670317232 24.851083320396626 0.9956575735705758 0.9698647699015902 0.02779875309804103 0.05774574344263388 2965.1816286803573 4715623.156945823 0.023605317397018093 0.01597480698101949 5.283653508205442e-08 7.277065670317232 -0.02579280366898562 EGHLSPDIVAEQK ddPTM_PC-9_Lapatinib_30min_R1 2 EGHLSPDIVAEQK 13 0 B4DLR8;P15559-3;P15559-2;P15559;H3BRK3;H3BNV2 B4DLR8 NQO1 NAD(P)H dehydrogenase [quinone] 1 0 ; 99.161 0.0021625999999999998 21870000.0 121424.0 192635.0 230338.0 270420.0 320900.0 404300.0 285770.0 242320.0 305710.0 162979.0 False True 119692.47149356562 192188.9654929593 211400.49877039244 290307.58889467496 302025.2929136741 387009.0314693319 300565.77231665095 253579.07183265247 271277.7205309835 191149.70299413288 0.6261713704950902 1.0054369035501893 1.1059420729357927 1.5187446506447653 1.5800458393751435 2.0246384138049676 1.5724103548613753 1.3265993504600726 1.4191898615678733 1.0 17.54434343297074 -5.337225720782728 1.438681857084977 1.5385951086200782 0.666445233066557 0.5457838402690973 0.25268907322377 0.4041306836824114 1.3969186463161185 0.07979764692414015 0.37445681331172814 4.6001742138112475e-06 5.337225720782728 -0.8721498755535212 EGHSINTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGHSINTR 8 0 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;A0A5F9ZH85;F8WB06;F8VRK6 Q99700;F8WB06 ATXN2 Ataxin-2 0 82.75 0.013451 281090.0 1022.1 3209.5 2263.2 1104.9 3188.2 2187.6 541.05 2537.0 3463.2 2361.1 False True 1195.1213426048093 3528.117949153439 2317.163271233796 1042.996035134132 2563.495096685196 2072.878404950296 489.79782713721704 2470.4064381736944 3513.8427482692946 2789.148739542683 0.42848964118018495 1.2649443534990248 0.8307779496957645 0.37394780003921363 0.9190958733543606 0.7431939270797624 0.17560835684135143 0.8857205795983292 1.259826232445902 1.0 11.445609157027166 -8.002694305607152 24.991398789588995 1.1108666520049322 0.6929093856671991 0.2727554769432703 0.2955766613968122 140.5312194781532 1303506.0672196993 0.1686016725206164 0.07867922023541891 9.938153363275534e-09 8.002694305607152 -0.4179572663377331 EGHSINTR ddPTM_PC-9_Lapatinib_30min_R1 2 EGHSINTR 8 0 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;A0A5F9ZH85;F8WB06;F8VRK6 Q99700;F8WB06 ATXN2 Ataxin-2 0 ; 80.219 0.016457 964150.0 5344.6 6671.7 7426.9 5318.7 7439.200000000001 3618.5 6513.9 8560.099999999999 8125.5 5554.1 False True 5268.385023920397 6656.252088558028 6816.288950663059 5709.854940663078 7001.6408820299275 3463.7451901354884 6851.157869242512 8957.833496181423 7210.320624691725 6514.118784626948 0.8087640397890147 1.0218192680591747 1.0463869597756217 0.8765352812015189 1.0748408362699053 0.531728896057251 1.0517397818122327 1.3751412573749102 1.106875828194565 1.0 12.66935431210695 -7.521321024387232 24.999369900056077 1.1872932776757645 0.9034698687309576 0.33371365575065204 0.16985832392773345 65.74027872208408 1055102.8576010976 0.07698390655387703 0.04526770659466669 3.010779675354233e-08 7.521321024387232 -0.28382340894480695 EGHSLEMENENLVENGADS(ph)DEDDNSFLK ddPTM_PC-9_AZD4547_30min_R2 2 EGHSLEMENENLVENGADSDEDDNSFLK 28 0 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 EGHSLEMENENLVENGADS(1)DEDDNSFLK;EGHSLEMENENLVENGADS(0.998)DEDDNS(0.002)FLK 175.75 3.827500000000001e-18 9764800.0 51117.0 53552.7 67524.4 61100.9 58342.6 60386.2 69320.6 79499.0 63003.0 67596.4 True False 67371.14270034926 70862.56299487357 66628.98233634088 47015.03150449471 50242.7370565817 56610.2413679697 75489.9991082039 67214.25625528155 66333.20995682628 65229.870610742895 1.0328265573663995 1.086351426599381 1.0214489422177018 0.7207592329142483 0.7702412496937726 0.8678576369680303 1.157291872594505 1.0304214254291628 1.016914633368929 1.0 15.993245146359415 -7.2460956904922345 24.888664059138343 1.053692108559752 0.913511633544111 0.24873354292268068 0.11447015345047726 1245.5038565301775 2020306.9307515856 0.05054975427828896 0.0390097758347218 5.674195689590873e-08 7.2460956904922345 -0.1401804750156409 EGHSLEMENENLVENGADS(ph)DEDDNSFLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGHSLEMENENLVENGADSDEDDNSFLK 28 0 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 EGHS(0.001)LEMENENLVENGADS(0.992)DEDDNS(0.008)FLK 52.059 0.034871 0.0 2449.8 4353.8 3649.0 3084.2 2977.4 4381.2 3378.6 4075.2 2852.6 2476.6 True False 2864.5027542444577 4786.016490738202 3736.0059989095653 2911.4022731113114 2393.9998434447366 4151.442159338193 3058.554549054248 3968.2303180313147 2894.313878411002 2925.587975245186 0.9791203609265556 1.6359161068595445 1.2770103071661894 0.9951511620043879 0.8182969931861651 1.4190112191004174 1.045449521577938 1.3563872806452684 0.9893101499258237 1.0 11.514510886699497 -1.5228787452803376 0.1286714818016173 0.99911817341717 1.9242829416188008 0.05601163115778052 0.2359267863418142 269.8789071638588 2.3639178398729483 1.344746139465072 45.19975121235528 0.029999999999999995 1.5228787452803376 0.9251647682016307 EGHSLEMENENLVENGADS(ph)DEDDNSFLK ddPTM_PC-9_Lapatinib_30min_R1 4 EGHSLEMENENLVENGADSDEDDNSFLK 28 0 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 EGHSLEMENENLVENGADS(0.999)DEDDNS(0.001)FLK;EGHSLEMENENLVENGADS(0.871)DEDDNS(0.129)FLK;EGHSLEMENENLVENGADS(0.996)DEDDNS(0.004)FLK;EGHSLEMENENLVENGADS(0.997)DEDDNS(0.003)FLK 136.49 2.424e-10 13547700.0 32453.8 52943.8 54289.6 49163.9 62768.0 52340.9 50923.9 57531.0 55402.0 52986.4 True False 31991.00286070199 52821.21188395736 49826.11865191634 52779.577211962634 59076.109646636054 50102.4017195972 53560.49036944367 60204.100287241214 49162.04335107634 62145.02864005996 0.5147797589086625 0.8499668121467037 0.8017715936781692 0.8492968523300324 0.9506168222851922 0.8062173727489469 0.8618628318551853 0.9687677615524087 0.7910856978732725 1.0 15.923351365466042 -4.43336629393154 1.7542187745004332 0.8782961950323138 2.6772836891409708e-17 0.7034402159086479 0.0701297768509019 1.48853466899525 2.0798986421387897 0.018085712834513743 2.946871658518789 3.6866652559828374e-05 4.43336629393154 -0.8782961950323138 EGIDPTPYYWYTDQR ddPTM_PC-9_Lapatinib_30min_R1 2 EGIDPTPYYWYTDQR 15 0 O43776 O43776 NARS Asparagine--tRNA ligase, cytoplasmic 0 ; 190.66 6.2777e-07 4878900.0 19094.6 17172.5 19959.0 20510.5 18096.5 21455.5 17907.699999999997 18721.2 18879.6 16957.5 False True 18822.307502479212 17132.738131325255 18318.048063968006 22018.910591022264 17032.0994490879 20537.898280213332 18834.873082950948 19591.055297100716 16753.18063699831 19888.581280551563 0.9463876400718926 0.8614359108700648 0.9210334214175783 1.107113186225801 0.8563757871328443 1.0326477283875808 0.9470194388057732 0.9850403616399834 0.8423517193446439 1.0 14.27965274709804 -5.537355912918851 24.999862891382712 0.9677259368199659 0.9007424304115367 0.11106140638518613 0.07560413065760901 440.8280208080942 761239.9867958125 0.01944812459585054 0.033702233765001706 2.901643725376491e-06 5.537355912918851 -0.0669835064084292 EGIILFK ddPTM_PC-9_Lapatinib_30min_R1 2 EGIILFK 7 0 P05455 P05455 SSB Lupus La protein 0 ; 110.35 0.043670999999999995 10546300.0 89653.0 72052.0 83850.0 77882.0 77292.0 80957.0 83888.0 76280.0 78302.0 74082.0 False True 88374.53177965335 71885.16802086153 76956.17667036029 83609.70208673568 72745.83652191867 77494.65782998451 88231.31017286352 79824.24727383096 69482.80420338582 86886.9749919397 1.0171205958988865 0.8273411294101348 0.8857044071047396 0.9622811945575497 0.837246739556385 0.8919018971160351 1.0154722290774714 0.9187136194030932 0.7996918319441041 1.0 16.406852302009952 EGIPALDNFLDKL ddPTM_PC-9_Lapatinib_30min_R1 1 EGIPALDNFLDKL 13 1 P13639 P13639 EEF2 Elongation factor 2 0 84.18799999999999 0.019676 3634400.0 24183.0 19092.0 27449.0 22029.0 29371.0 25150.0 23237.0 24936.0 26995.0 26367.0 False True 23838.145985380932 19047.793647008973 25192.249176204106 23649.086146589754 27643.455525607755 24074.393127513475 24440.098160485788 26094.617593343548 23954.538830047757 30924.500818180943 0.7708498231074487 0.615945064368202 0.8146372135259572 0.7647362292323933 0.8939014307178658 0.7784893042916898 0.7903150419203248 0.8438169381218326 0.7746135975124472 1.0 14.916462687024424 -14.52287874527947 0.08360276609210171 1.6639155641603174 0.593493780934189 0.5376287784324059 0.06375081445221074 188.11478786877234 1.1021440060264203 23.045522067465686 1.9283660358133243 3.0000000000059893e-15 14.52287874527947 -1.0704217832261285 EGIREETVSLR ddPTM_PC-9_AZD4547_30min_R2 2 EGIREETVSLR 11 1 P20618 P20618 PSMB1 Proteasome subunit beta type-1 0 ; 117.25 0.0015305 10993300.0 26591.0 33356.0 39322.0 56160.0 41754.0 45169.0 34526.0 55544.0 37907.0 36207.0 False True 35046.38487284056 44137.67468786833 38800.56458746162 43213.17966335066 35957.17782650264 42344.57528954998 37598.747114275444 46960.951074143726 39910.68663132571 34939.40395055309 1.003061898893263 1.263263527630088 1.1105102033902157 1.2368035735385405 1.0291296862817099 1.2119432646726553 1.0761130088963713 1.3440684660964384 1.1422829847872642 1.0 15.092567376329708 EGIREETVSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGIREETVSLR 11 1 P20618 P20618 PSMB1 Proteasome subunit beta type-1 0 107.03 0.0041412 0.0 9593.0 10296.0 12576.0 11866.0 17868.0 12936.0 13652.0 9871.1 13164.0 9859.1 False True 11216.905429613473 11318.118836106501 12875.85953474559 11201.186490091055 14366.893666511236 12257.613387473499 12358.783728079254 9611.994084294975 13356.498596158754 11646.476785407347 0.963115767651543 0.9718062418917739 1.1055583394008581 0.961766094285765 1.233582819184638 1.0524739466987894 1.061160723178052 0.8253134627236357 1.146827391859314 1.0 13.50760596593377 -10.632043186551812 10.824181703793112 0.999999999950372 1.034602234940753 0.009678743636726717 0.10789245766056134 0.0 0.0 0.1027702265826098 0.024925440953629828 2.3332260330903207e-11 10.632043186551812 0.034602234990381064 EGIREETVSLR ddPTM_PC-9_Lapatinib_30min_R1 3 EGIREETVSLR 11 1 P20618 P20618 PSMB1 Proteasome subunit beta type-1 0 ;; 145.23 0.00022679 15604100.0 42952.3 54238.8 68150.4 48931.0 56579.0 62075.0 46635.7 48995.4 61425.2 54675.0 False True 42339.79232551287 54113.21339102198 62547.337180151524 52529.548969030984 53251.134458593835 59420.196953892606 49050.26835576739 51271.905150501465 54506.84713996845 64125.50090014192 0.6602645083653322 0.8438641824457425 0.9753894519678223 0.8191678541557362 0.830420561416246 0.9266235135757217 0.7649104906353852 0.7995556281165516 0.8500026724913711 1.0 15.968610569560811 -4.768601958755012 5.263211701059654 0.8616307348620421 0.6502222823101642 0.42443189352503097 0.07243570279233848 0.1521963868138365 12.18997960572083 0.017799778775003012 0.11687999883682677 1.7037192923810356e-05 4.768601958755012 -0.2114084525518779 EGITGPPADSSKPIGPDDAIDALSS(ph)DFTCGSPTAAGK ddPTM_PC-9_AZD4547_30min_R2 1 EGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGK 37 1 P20810-6;P20810-7;P20810-10;P20810-9;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;H0YA91 P20810-6 CAST Calpastatin 1 EGITGPPADSSKPIGPDDAIDALS(0.054)S(0.476)DFT(0.237)CGS(0.188)PT(0.045)AAGK 54.997 0.0001294 19001000.0 72450.0 63876.0 79502.0 98552.0 85380.0 93621.0 78133.0 104840.0 82477.0 84936.0 True False 95487.59294638384 84522.66783673927 78447.75153431608 75832.35901322182 73526.4607660774 87766.86407011373 85086.6856363227 88639.38698353087 86836.56583986731 81962.41649250618 1.1650168093215538 1.0312368943449488 0.957118578141099 0.925208922069241 0.8970753171095185 1.0708184046542633 1.0381183141922392 1.0814638071540408 1.0594681020392656 1.0 16.32267489940815 EGITGPPADSSKPIGPDDAIDALSSDFT(ph)CGSPTAAGK ddPTM_PC-9_AZD4547_30min_R2 1 EGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGK 37 1 P20810-6;P20810-7;P20810-10;P20810-9;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;H0YA91 P20810-6 CAST Calpastatin 1 EGITGPPADSSKPIGPDDAIDALS(0.065)S(0.079)DFT(0.428)CGS(0.346)PT(0.083)AAGK 86.785 1.1811e-13 6694900.0 19276.0 19899.0 26390.0 28597.0 27438.0 22373.0 24074.0 25634.0 21211.0 24070.0 True False 25405.367034292587 26330.962603846136 26040.05135708032 22004.40346924572 23628.707314355015 20974.01277320954 26216.5393624824 21672.854310719435 22332.17015688525 23227.316626337815 1.0937710732149337 1.1336205136149498 1.1210959826307745 0.9473502179883571 1.0172809754339878 0.9029890585564576 1.1286942777003806 0.9330761128964957 0.9614614772832801 1.0 14.503534873623625 -5.752003533536946 24.998383430782035 0.985608199053543 1.1179083715012799 0.5161468280714867 0.05844300108385209 154.2269974548934 408589.6220914826 0.015385219452930485 0.026204889735764996 1.7700945562924844e-06 5.752003533536946 0.13230017244773684 EGITGPPADSSKPIGPDDAIDALSSDFT(ph)CGSPTAAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGK 37 1 P20810-6;P20810-7;P20810-10;P20810-9;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;H0YA91 P20810-6 CAST Calpastatin 1 EGITGPPADSSKPIGPDDAIDALS(0.001)S(0.006)DFT(0.667)CGS(0.324)PT(0.003)AAGK;EGITGPPADSSKPIGPDDAIDALS(0.003)S(0.032)DFT(0.658)CGS(0.305)PT(0.002)AAGK 128.05 2.2394999999999997e-26 27057500.0 156593.0 160628.0 154735.0 186078.0 206144.0 207941.0 206377.0 188387.0 162861.0 170799.0 True False 183101.1020472704 176574.08628653048 158424.4692357556 175652.65293301526 165751.5630170859 197036.20790079047 186827.47651991 183442.0408625257 165242.53402225854 201763.50665585996 0.9075035673303334 0.8751537342563436 0.7851988293699412 0.8705868362637998 0.821514087281412 0.9765701001463428 0.9259725884848653 0.9091933615894946 0.818991188055163 1.0 17.62230572951701 -6.747252219903175 24.98383906331647 0.9204592392476172 0.8506005860935627 0.31668888653686555 0.054122018058825876 315.39351207059104 555412.4460740584 0.017984469644208627 0.017902081058288326 1.789566247647136e-07 6.747252219903175 -0.06985865315405448 EGITGPPADSSKPIGPDDAIDALSSDFT(ph)CGSPTAAGK ddPTM_PC-9_Lapatinib_30min_R1 1 EGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGK 37 1 P20810-6;P20810-7;P20810-10;P20810-9;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;H0YA91 P20810-6 CAST Calpastatin 1 EGITGPPADSSKPIGPDDAIDALS(0.018)S(0.083)DFT(0.482)CGS(0.335)PT(0.083)AAGK 74.846 3.7445e-09 14799000.0 62995.0 79068.0 85872.0 96213.0 100770.0 101300.0 90579.0 97360.0 98112.0 85674.0 True False 62096.67974813184 78884.92290392358 78811.93563550575 103288.82497715908 94842.90672144266 96967.63514183369 95268.73741354921 101883.70103015445 87061.59339483785 100482.63674657095 0.6179841787466922 0.7850602398390545 0.7843338728687896 1.0279270958789195 0.9438735864450656 0.9650188160009922 0.9481114399279569 1.0139433471189372 0.8664342040945586 1.0 16.616586701773528 -5.203260773526917 1.2735829875722846 0.9656088268605911 0.6056761090030464 0.7888004888167516 0.05718596472561105 0.31023079299576883 0.7134644427454777 0.016923925068837005 0.12001961204906293 6.262377252880976e-06 5.203260773526917 -0.35993271785754477 EGITGPPADSSKPIGPDDAIDALSSDFT(ph)CGSPTAAGKK ddPTM_PC-9_Lapatinib_30min_R1 1 EGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKK 38 2 P20810-6;P20810-7;P20810-10;P20810-9;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;H0YA91 P20810-6 CAST Calpastatin 1 EGITGPPADSSKPIGPDDAIDALS(0.092)S(0.092)DFT(0.361)CGS(0.361)PT(0.092)AAGKK 61.24100000000001 3.7358000000000004e-05 38448000.0 37514.0 38873.0 35935.0 38891.0 40006.0 43219.0 31638.0 38315.0 47558.0 33386.0 True False 36979.043480774955 38782.99195684999 32980.563013111394 41751.17387657282 37652.925734822216 41370.62411840975 33276.06083407708 40095.25477578433 42201.51723205821 39156.7256159513 0.9443854893145299 0.9904554414797886 0.8422707081430753 1.0662580494106642 0.9615953617808002 1.0565394186473185 0.8498172487773439 1.0239685301840127 1.0777590967633555 1.0 15.25697250774087 -6.489444062012586 0.36267449760719583 1.02050289410016 0.9312809781753131 0.09169498024650058 0.07552894148111591 5.589933956033739 1.3663775896835872 0.08339932290732434 0.19470748580948957 3.2400815263760487e-07 6.489444062012586 -0.08922191592484685 EGITGPPADSSKPIGPDDAIDALSSDFTCGS(ph)PTAAGK ddPTM_PC-9_AZD4547_30min_R2 1 EGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGK 37 1 P20810-6;P20810-7;P20810-10;P20810-9;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;H0YA91 P20810-6 CAST Calpastatin 1 EGITGPPADSSKPIGPDDAIDALS(0.006)S(0.094)DFT(0.319)CGS(0.574)PT(0.006)AAGK 108.99 1.1649000000000001e-23 18999000.0 88681.0 79191.0 110550.0 118730.0 107080.0 113580.0 96586.0 110720.0 106110.0 119750.0 True False 116879.71332061118 104787.94208559128 109084.03476791327 91358.63286021417 92213.79033534277 106477.82464493565 105181.96688812513 93610.76809248865 111718.7579721415 115557.58894906349 1.0114412595795026 0.9068027728735379 0.9439798438161973 0.7905896418493471 0.7979899128562608 0.921426499231218 0.910212542894852 0.8100789307204328 0.9667799318778266 1.0 16.818252482660036 -10.511997274459661 14.985590317624501 0.9999999923305891 0.8899701221169668 0.16057120874871078 0.07069234241287341 0.0 0.0 0.06977305769439017 0.016922452284687136 3.076116119734467e-11 10.511997274459661 -0.11002987021362232 EGITGPPADSSKPIGPDDAIDALSSDFTCGS(ph)PTAAGKK ddPTM_PC-9_AZD4547_30min_R2 1 EGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKK 38 2 P20810-6;P20810-7;P20810-10;P20810-9;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;H0YA91 P20810-6 CAST Calpastatin 1 EGITGPPADSS(0.001)KPIGPDDAIDALS(0.061)S(0.061)DFT(0.061)CGS(0.626)PT(0.19)AAGKK 44.178000000000004 0.0025177 139710000.0 81879.0 69226.0 91588.0 134800.0 104630.0 92185.0 83668.0 113560.0 106580.0 93709.0 True False 107914.81881100043 91601.95071178718 90373.48327746386 103723.9426392392 90103.93054526433 86420.65737712079 91114.28991360695 96011.91134919654 112213.60121261758 90428.27643279968 1.1933747171571447 1.0129790628029907 0.9993940705551704 1.1470299637560821 0.9964132249299655 0.9556817931982029 1.0075862717710544 1.061746559114684 1.240912750294509 1.0 16.464486345670394 -10.143179503200413 0.00290067499484312 0.00021573831495611247 2.0889652655170776 0.008832757115396106 0.09191117889572051 601932.0015217637 389.1022425613844 142148.32480209676 138051.43493501452 7.191516757945339e-11 10.143179503200413 2.0887495272021215 EGKDVNSS(ph)SPVMLAFK ddPTM_PC-9_AZD4547_30min_R2 1 EGKDVNSSSPVMLAFK 16 1 Q9NRI2;C4P0D4;Q5VVQ1;C4P0D6;C4P0D8;Q99598 Q9NRI2 TRAX;DISC1;TSNAX Translin-associated protein X 1 EGKDVNS(0.017)S(0.492)S(0.492)PVMLAFK 66.779 0.012326 7468000.0 22627.0 11004.0 21143.0 48558.0 39966.0 29845.0 24723.0 24306.0 17585.0 27897.0 True False 29821.915329162624 14560.827805051646 20862.630005409213 37363.703313621496 34417.41076337607 27978.787432013523 26923.299105202783 20550.066196315303 18514.507199510983 26920.334521185952 1.1077839803845366 0.5408858420237113 0.7749766255315511 1.3879360705646784 1.2784911991450187 1.0393179702129847 1.0001101243379609 0.7633659299494465 0.6877517508164807 1.0 14.716408717025818 -11.981541176649271 2.045600081439898 1.375895005940539 0.9566748289745199 0.0029094504016686784 0.2523262204555317 37215319.58949067 2361711.9971246705 65059615.736540616 0.07525165929322068 1.0434191986066629e-12 11.981541176649271 -0.4192201769660191 EGKDVNSSS(ph)PVMLAFK ddPTM_PC-9_AZD4547_30min_R2 1 EGKDVNSSSPVMLAFK 16 1 Q9NRI2;C4P0D4;Q5VVQ1;C4P0D6;C4P0D8;Q99598 Q9NRI2 TRAX;DISC1;TSNAX Translin-associated protein X 1 EGKDVNS(0.001)S(0.008)S(0.991)PVMLAFK 79.565 0.015646 0.0 23480.0 14384.0 22161.0 38365.0 30232.0 25866.0 19018.0 26107.0 17182.0 22574.0 True False 30946.151585660395 19033.346705549164 21867.130660259823 29520.541983341325 26034.80864230557 24248.594931025695 20710.565157252226 22072.763029178153 18090.205442251776 21783.691130990836 1.4206110158087246 0.8737429571093734 1.0038303668908655 1.3551671204768214 1.1951513857661538 1.1131536333862233 0.9507371837359595 1.0132701063584246 0.8304472062824799 1.0 14.410960811344802 -7.205874432717127 3.4125110203448092 0.9468686269246067 1.1545233518423164 0.31623634847318294 0.15338523403763413 0.3454045636862083 8.09805866120739 0.06598904582185161 0.04786806335708347 6.22480236461772e-08 7.205874432717127 0.20765472491770964 EGKDVNSSS(ph)PVMLAFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGKDVNSSSPVMLAFK 16 1 Q9NRI2;C4P0D4;Q5VVQ1;C4P0D6;C4P0D8;Q99598 Q9NRI2 TRAX;DISC1;TSNAX Translin-associated protein X 1 EGKDVNS(0.003)S(0.022)S(0.975)PVMLAFK 76.329 0.017608000000000002 10044000.0 87432.0 44652.0 74923.0 125500.0 137530.0 146550.0 110730.0 144830.0 136570.0 92397.0 True False 102232.5107392852 49084.7554652125 76709.44846705966 118468.64187648958 110581.98376736559 138864.66001346943 100240.85278422307 141028.36596006964 138567.07788494378 109147.84468575062 0.9366425057097968 0.44970888437177337 0.7028031445597035 1.0853960718837337 1.013139417326508 1.2722620443241641 0.9183951645845887 1.292085669360735 1.269535631087307 1.0 16.735924116521083 -5.769944063092752 4.230117328786072 1.1313619677046982 0.6638965887249706 0.5917872643959552 0.16176228054360559 0.12807777268835663 5.295188996822547 0.04451679496420133 0.07350218541082719 1.698462399462949e-06 5.769944063092752 -0.4674653789797276 EGLEEGDQILR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGLEEGDQILR 11 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 0 86.189 0.046297000000000005 0.0 7261.5 8948.8 8124.3 9200.8 13009.0 8818.8 9573.7 9236.3 9290.9 7953.6 False True 8490.728528837511 9837.177723441133 8318.014123579322 8685.309005396066 10459.97983588788 8356.326603389867 8666.809828414329 8993.85691166878 9426.761835844074 9395.524719337047 0.9036992379321441 1.0470067417517528 0.885316613180732 0.9244091484875477 1.1132938445002507 0.8893943502901553 0.9224402135387989 0.9572490286953755 1.0033246803600802 1.0 13.197758019894044 -6.186314896809856 0.004429109321447944 1.9206122144540576 1.6815077645603374e-08 0.03279754135765911 0.0700617019887705 112168.82500148092 136.23716166793645 29009.3983097431 30067.767902872445 6.511560847460489e-07 6.186314896809856 -1.92061219763898 EGLEEGDQILR ddPTM_PC-9_Lapatinib_30min_R1 2 EGLEEGDQILR 11 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 0 ; 123.51 0.0025949000000000002 3398700.0 19187.3 19363.0 20824.1 20303.0 20254.3 20107.0 19190.2 15649.3 21567.0 17780.6 False True 18913.68558348011 19318.166163159185 19112.022881350586 21796.150348822546 19062.98189548592 19247.070481706298 20183.774657630263 16376.42360857842 19137.897349421728 20853.953018839755 0.9069592497112283 0.9263551205714754 0.9164700267658853 1.0451807544177163 0.9141183869678882 0.9229459021183285 0.9678632458506048 0.7852910953517411 0.9177107732108287 1.0 14.34803326250571 EGLELLK ddPTM_PC-9_Lapatinib_30min_R1 1 EGLELLK 7 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 119.21 0.030355 52931000.0 160380.0 136560.0 147950.0 149870.0 155210.0 134920.0 154570.0 128300.0 116480.0 151900.0 False True 158092.95178991003 136243.8037102213 135786.12210351552 160891.93975166415 146080.8529546008 129149.78611388146 162572.87828318152 134261.2863821776 103360.79581122285 178155.71260597286 0.8873863738490628 0.764745635811027 0.762176638162784 0.9030972815758593 0.8199616549915968 0.7249264378040021 0.9125325026357369 0.7536176326780125 0.5801711003218067 1.0 17.442779219014803 -7.953577291869283 24.9996749196177 0.7490208471634944 0.8201978126334021 0.015528452209512378 0.11266373999609457 314.7428578452234 169495.49208366618 0.05799035782812073 0.027857652936410328 1.1128143263808034e-08 7.953577291869283 0.0711769654699077 EGLELPEDEEEK ddPTM_PC-9_AZD4547_30min_R2 2 EGLELPEDEEEK 12 0 P07900;P07900-2;Q58FG0;Q58FF6;P08238;Q58FF7 P07900;P08238 HSP90AA1;HSP90AA5P;HSP90AB4P;HSP90AB1;HSP90AB3P Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-alpha A5;Putative heat shock protein HSP 90-beta 4;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 ; 192.3 0.00027821 10065200.0 47136.0 56238.0 39173.0 30115.0 34703.0 50695.0 51916.0 49907.0 53484.0 43240.0 False True 62124.267510293364 74415.83370597009 38653.54042481651 23172.452022111913 29885.08746738324 47525.03363598347 56536.423425381516 42195.01989877021 56311.05505024992 41726.180761231706 1.4888558304864978 1.7834326638183653 0.926361812167817 0.555345627118639 0.7162190960728865 1.1389739671582775 1.3549388511950795 1.0112360903630584 1.3495377248274107 1.0 15.348665254883779 -6.996300725045679 24.931275651879375 1.189449108117674 1.0765489734143097 0.011466155256333876 0.3484816053661222 662.6184313079494 4465676.061315476 0.14103341124327323 0.12378317985613238 1.0085542758571402e-07 6.996300725045679 -0.11290013470336424 EGLELPEDEEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EGLELPEDEEEK 12 0 P07900;P07900-2;Q58FG0;Q58FF6;P08238;Q58FF7 P07900;P08238 HSP90AA1;HSP90AA5P;HSP90AB4P;HSP90AB1;HSP90AB3P Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-alpha A5;Putative heat shock protein HSP 90-beta 4;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 ; 199.03 3.4716e-05 10064800.0 52140.0 87374.0 52600.0 51552.0 64349.0 39898.0 69327.0 39287.0 40271.0 40816.0 False True 60966.27218805862 96047.91328535072 53854.18348661087 48663.70857383902 51740.2753831616 37805.67864358515 62759.844675985325 38255.75787801734 40859.88718975302 48215.6177007218 1.2644507131793095 1.992049835004247 1.1169448003526181 1.00929347988236 1.0731019916475535 0.7840961175328713 1.3016497074773719 0.793430836362481 0.8474409151693049 1.0 15.55721291044127 -5.430928071230443 6.047860765435809 0.980191162066291 1.6242024778043587 0.5865510838530723 0.2168096954982278 0.14236672674960696 7.594860936293391 0.0536903306386657 0.11300925955022478 3.7074211979108916e-06 5.430928071230443 0.6440113157380677 EGLELPEDEEEK ddPTM_PC-9_Lapatinib_30min_R1 3 EGLELPEDEEEK 12 0 P07900;P07900-2;Q58FG0;Q58FF6;P08238;Q58FF7 P07900;P08238 HSP90AA1;HSP90AA5P;HSP90AB4P;HSP90AB1;HSP90AB3P Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-alpha A5;Putative heat shock protein HSP 90-beta 4;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 ;; 136.81 0.00029722 33127400.0 108422.0 111361.0 93929.0 98480.0 106644.0 77397.0 118768.0 107599.0 81721.0 116256.0 False True 106875.88239784054 111103.15044649964 86206.5201964254 105722.54771964949 100371.4095901711 74086.91073121913 124917.22590371297 112598.44234946139 72516.7204197197 136350.69469861747 0.7838308608113326 0.8148337688493359 0.6322411512971887 0.7753722704041454 0.7361268661815539 0.5433555794855098 0.9161466040185827 0.82580028358743 0.5318397576191812 1.0 17.05696252515348 -11.674744314760693 2.390978325028792 1.616037685527444 0.733015234541795 0.3207235019504485 0.11824730363753622 9876957.519736383 1824993.8345640271 33129733.512992606 0.029620488560986754 2.1147336954283395e-12 11.674744314760693 -0.8830224509856491 EGLELPEDEEEKK ddPTM_PC-9_AZD4547_30min_R2 2 EGLELPEDEEEKK 13 1 P07900;P07900-2;Q58FG0;Q58FF6;P08238;Q58FF7 P07900;P08238 HSP90AA1;HSP90AA5P;HSP90AB4P;HSP90AB1;HSP90AB3P Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-alpha A5;Putative heat shock protein HSP 90-beta 4;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 ; 124.21 9.905299999999999e-05 12497800.0 79129.0 68096.0 68117.0 73785.0 74931.0 79556.0 73135.0 65243.0 63853.0 68272.0 False True 104290.37601455375 90106.70031014159 67213.72407314288 56775.00821688625 64528.12405320846 74581.35074355078 79643.87331873174 55161.19348499136 67228.13922151686 65881.81806037965 1.5829917735265482 1.3677020908494089 1.020216594683871 0.861770514056744 0.9794526920017516 1.1320475502846346 1.2088900346638793 0.8372749130031141 1.0204353978195218 1.0 16.00759274746288 -5.1017109475870495 2.702522253967482 1.005330824574083 1.569576568527118 0.772737333396492 0.10453381023358603 0.14376202649910286 1.9133854882120667 0.03012764346305836 0.1286999431283025 7.912050533831592e-06 5.1017109475870495 0.5642457439530348 EGLELPEDEEEKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGLELPEDEEEKK 13 1 P07900;P07900-2;Q58FG0;Q58FF6;P08238;Q58FF7 P07900;P08238 HSP90AA1;HSP90AA5P;HSP90AB4P;HSP90AB1;HSP90AB3P Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-alpha A5;Putative heat shock protein HSP 90-beta 4;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 91.09299999999999 0.0033442 5407600.0 25614.0 30087.0 16460.0 27647.0 23430.0 19005.0 28469.0 21168.0 19646.0 15708.0 False True 29949.94430043985 33073.83852194408 16852.468824897613 26098.028222783367 18839.059693662304 18008.34434360959 25772.210222288923 20612.36242934994 19933.28558341955 18555.73605554042 1.6140531537414986 1.7824050968901777 0.9082080481450779 1.4064668814358863 1.0152687900535904 0.9705001348212545 1.3889079983218338 1.1108350737288835 1.0742384739552178 1.0 14.179577609505195 -5.2532085331347265 24.99470290074917 1.1255448227939142 1.698229189093115 0.6763879106274687 0.16263265264785365 337.3671944865303 1024480.7728233625 0.04002242406856138 0.10214603548218935 5.582021011050403e-06 5.2532085331347265 0.5726843662992007 EGLELPEDEEEKK ddPTM_PC-9_Lapatinib_30min_R1 1 EGLELPEDEEEKK 13 1 P07900;P07900-2;Q58FG0;Q58FF6;P08238;Q58FF7 P07900;P08238 HSP90AA1;HSP90AA5P;HSP90AB4P;HSP90AB1;HSP90AB3P Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-alpha A5;Putative heat shock protein HSP 90-beta 4;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 104.41 0.00084952 15534000.0 107690.0 101670.0 109610.0 82355.0 96173.0 79846.0 110080.0 98488.0 79347.0 110420.0 False True 106154.32085207256 101434.58936158611 100598.28890683576 88411.66142822639 90516.29322339283 76431.17271011695 115779.40377442342 103064.11202812093 70410.10529904788 129505.94987459818 0.8196868248513893 0.7832426962607214 0.7767850743865129 0.6826841663555707 0.6989354026671407 0.5901749902929245 0.8940083748008002 0.795825304767224 0.543682397351061 1.0 16.98265885541729 -9.940056693629023 8.187995336557366 0.9999999970913492 0.734609758485121 0.388625559503025 0.10090633052150959 0.0 0.0 0.0981376403538447 0.023801873942810584 1.1480037491183615e-10 9.940056693629023 -0.26539023860622823 EGLEQALPSGKPS(ph)SPVELDLFGDPSPSSK ddPTM_PC-9_AZD4547_30min_R2 1 EGLEQALPSGKPSSPVELDLFGDPSPSSK 29 1 Q9H201 Q9H201 EPN3 Epsin-3 1 EGLEQALPS(0.022)GKPS(0.489)S(0.489)PVELDLFGDPSPSSK 71.265 3.4142e-05 3116800.0 7211.9 9188.0 8745.8 9444.2 10260.0 12664.0 9995.3 11892.0 9305.9 10923.0 True False 9505.134183161173 12157.8413188672 8629.82497759579 7266.985601435479 8835.57610049138 11872.118078037167 10884.862336538186 10054.364650974312 9797.79087562861 10540.589094702449 0.9017649865450423 1.1534309144996042 0.8187232136705735 0.6894287915167628 0.8382431020797515 1.1263239626714912 1.0326616699259024 0.9538712268014976 0.9295297243446139 1.0 13.363667878427437 -6.7370917167610465 24.999485058994694 1.0071058678594544 0.8814642046796523 0.22568229787296934 0.11867126698363331 417.7660996793376 428949.3570633817 0.043610489719905145 0.04359067224136208 1.8319275047220145e-07 6.7370917167610465 -0.1256416631798022 EGLGQGQS(ph)LEQLEALVQTK ddPTM_PC-9_AZD4547_30min_R2 2 EGLGQGQSLEQLEALVQTK 19 0 Q9NSC5-5;Q9NSC5-2;Q9NSC5;M0QYF9 Q9NSC5-5 HOMER3 Homer protein homolog 3 1 EGLGQGQS(1)LEQLEALVQTK;EGLGQGQS(1)LEQLEALVQTK 136.46 3.282e-05 13879300.0 39496.0 54060.0 73647.0 74148.0 77468.0 88101.0 87892.0 109627.0 94343.0 80105.0 True False 52054.906432165386 71533.83779908139 72670.39265990508 57054.32417518026 66712.90539501632 82592.0305427314 95714.21773063502 92686.66612784764 99329.77837494829 77300.5483320645 0.6734092778818344 0.9253988405333076 0.940101903905398 0.7380843397137192 0.8630327576517799 1.0684533593207641 1.2382087811262326 1.1990428027714382 1.2849815495260335 1.0 16.238191027504804 -6.878410553042583 2.825608814728401 1.195282121896086 0.8311555344358956 0.7318624017656605 0.10159784974099234 0.13499935639798863 2.176715731079722 0.038364083914900544 0.03330808324688178 1.323090182585879e-07 6.878410553042583 -0.36412658746019044 EGLGQGQS(ph)LEQLEALVQTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGLGQGQSLEQLEALVQTK 19 0 Q9NSC5-5;Q9NSC5-2;Q9NSC5;M0QYF9 Q9NSC5-5 HOMER3 Homer protein homolog 3 1 EGLGQGQS(1)LEQLEALVQTK 156.15 1.6405e-05 2344200.0 10502.0 12865.0 17641.0 17892.0 18329.0 17124.0 16411.0 12792.0 14863.0 14062.0 True False 12279.781176045108 14142.152178176979 18061.62834386505 16889.569246646653 14737.564025827425 16225.987294920847 14856.431274649052 12456.22355424435 15080.343256966542 16611.32928526925 0.7392413313325074 0.8513558388562009 1.0873078267060727 1.0167500117900945 0.8871995595738711 0.9768024591090299 0.8943553534769536 0.7498631410124653 0.9078348275438516 1.0 14.019879905982298 -7.519976055572198 24.972719240580346 0.8617312539282056 0.9329059269472806 0.013943707341789846 0.10620753624702232 339.25091199683834 2918762.7611139943 0.05093784529936244 0.03013238716395175 3.0201182272594246e-08 7.519976055572198 0.07117467301907499 EGLLLWCQR ddPTM_PC-9_AZD4547_30min_R2 2 EGLLLWCQR 9 0 O43707;P12814-4;P12814-3;P12814;P12814-2;H9KV75;P35609-2;P35609;A0A494C1A0;Q08043;G3V2N5;A0A087WSZ2;A0A494C033;G3V2W4;A0A494C166;G3V2X9 O43707;P12814-4 ACTN4;ACTN1;ACTN2;ACTN3 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2;Alpha-actinin-3 0 ; 116.25 0.0088914 20373000.0 98321.0 85701.0 105610.0 163351.0 145356.0 121726.0 96371.0 146538.0 108329.0 115939.0 False True 129585.03279615508 113402.17227560277 104209.54239565176 125692.95069779208 125175.82842719517 114114.45397719144 104947.83230463511 123893.91920824687 114055.0497819634 111880.01089908497 1.158250090921424 1.0136053023617488 0.9314402238452415 1.123462088425843 1.1188399734792924 1.019971781019238 0.9380391676874019 1.107382080253803 1.0194408175812595 1.0 16.771592773907486 -6.940950660542277 24.99927617733386 1.018568917462551 1.0622057132754117 0.11508385438666036 0.07096781102620005 221.27475541079878 93678.10911812319 0.02620516299095427 0.023110780651417733 1.1456430886160287e-07 6.940950660542277 0.04363679581286073 EGLLLWCQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGLLLWCQR 9 0 O43707;P12814-4;P12814-3;P12814;P12814-2;H9KV75;P35609-2;P35609;A0A494C1A0;Q08043;G3V2N5;A0A087WSZ2;A0A494C033;G3V2W4;A0A494C166;G3V2X9 O43707;P12814-4 ACTN4;ACTN1;ACTN2;ACTN3 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2;Alpha-actinin-3 0 104.44 0.012454999999999999 10700000.0 33919.0 36283.0 36313.0 34419.0 34310.0 32650.0 36921.0 34414.0 29031.0 24288.0 False True 39660.8167692129 39884.93645400664 37178.83963781938 32490.61501790357 27587.201796395813 30937.776522959924 33423.57559510802 33510.668964647055 29455.523453743903 28691.22213629779 1.3823327769310068 1.390144214301261 1.2958262795917552 1.1324235288255322 0.9615206234625586 1.0783011046371558 1.1649408113857667 1.1679763519816082 1.0266388553898225 1.0 14.808321802254264 -5.7001803982429085 2.6850498404342598 1.0779958565657624 1.3811601501227755 0.8161680572956923 0.06230250068684481 0.1181611955426142 1.725188372930175 0.019423965234291723 0.03668003709883189 1.9944336904194634e-06 5.7001803982429085 0.30316429355701313 EGLLLWCQR ddPTM_PC-9_Lapatinib_30min_R1 2 EGLLLWCQR 9 0 O43707;P12814-4;P12814-3;P12814;P12814-2;H9KV75;P35609-2;P35609;A0A494C1A0;Q08043;G3V2N5;A0A087WSZ2;A0A494C033;G3V2W4;A0A494C166;G3V2X9 O43707;P12814-4 ACTN4;ACTN1;ACTN2;ACTN3 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2;Alpha-actinin-3 0 ; 123.98 0.0067883 41361000.0 130173.0 94447.0 107694.0 97995.0 128960.0 113179.0 99809.0 92608.0 109431.0 95921.0 False True 128316.70914919532 94228.31377430633 98839.81503086201 105201.87920173687 121374.82634511501 108338.59800313496 104976.6216508122 96910.90576212545 97105.72842048365 112500.81704330171 1.1405846865965965 0.8375789283204736 0.8785697529007139 0.9351210237099392 1.0788795098118948 0.9630027661171144 0.9331187489101218 0.8614240172569086 0.8631557616431135 1.0 16.77957595356836 -4.745589156224949 24.983673205050778 0.9282083599147918 1.1405852819838036 0.45636396327396966 0.06964773768002572 928.2237692884206 1463018.4676143588 0.018820862644212392 0.47116602073613323 1.796432253108471e-05 4.745589156224949 0.21237692206901182 EGLRPGDT(ph)TSTFCGTPNYIAPEILR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGLRPGDTTSTFCGTPNYIAPEILR 25 1 P41743 P41743 PRKCI Protein kinase C iota type 1 EGLRPGDT(0.457)T(0.179)S(0.179)T(0.132)FCGT(0.053)PNYIAPEILR 55.63399999999999 0.0043965 20551000.0 39604.0 42831.0 34701.0 52129.0 44387.0 41381.0 46967.0 39503.0 38589.0 31965.0 True False 46308.1749853447 47082.9786197822 35528.40344427537 49208.38113449828 35689.68598474559 39210.907512912854 42517.94574836644 38466.08810688825 39153.291121784394 37760.0014651992 1.2263817052026273 1.2469008684540266 0.9409004784340238 1.30318800913846 0.9451717319883667 1.038424417145504 1.126004875491128 1.0186993277089726 1.0368985593888096 1.0 15.204571200230019 -1.5228787452803456 0.3820053603523685 1.028902632654263 4.276611804486861 0.2962279411657843 0.10336068470072234 85.71648695151177 1.167100482996222 0.07546827348493844 206.42696382726967 0.029999999999999444 1.5228787452803456 3.2477091718325983 EGLRPGDTT(ph)STFCGTPNYIAPEILR ddPTM_PC-9_Lapatinib_30min_R1 1 EGLRPGDTTSTFCGTPNYIAPEILR 25 1 P41743 P41743 PRKCI Protein kinase C iota type 1 EGLRPGDT(0.073)T(0.305)S(0.305)T(0.305)FCGT(0.011)PNYIAPEILR 68.634 0.00043789999999999996 22839000.0 47446.0 96546.0 57578.0 57682.0 84136.0 65260.0 83759.0 77698.0 68095.0 58880.0 True False 46769.4113394692 96322.45366876865 52844.15909750744 61924.12670151123 79187.2858977404 62468.98192849022 88095.63118406538 81308.13273049428 60425.42402786073 69057.32954733164 0.6772548496450854 1.3948186861577032 0.7652215839201869 0.8967060717149317 1.146689083067797 0.9045959688561981 1.2756883557694618 1.1774004767266013 0.8750037747469712 1.0 16.07550692568237 -6.257305403957703 24.841281243205348 1.0747908874621723 0.9544317071610883 0.07911176761156258 0.20986499947256954 976.2988133945688 5866628.87601041 0.061079416066004984 0.07601618037656531 5.529611199147169e-07 6.257305403957703 -0.12035918030108406 EGLRPGDTTS(ph)TFCGTPNYIAPEILR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGLRPGDTTSTFCGTPNYIAPEILR 25 1 P41743 P41743 PRKCI Protein kinase C iota type 1 EGLRPGDT(0.178)T(0.178)S(0.287)T(0.287)FCGT(0.066)PNY(0.003)IAPEILR 41.275 0.040755 9415000.0 16154.0 20480.0 16071.0 20526.0 20023.0 15729.0 23078.0 19426.0 16593.0 13281.0 True False 18888.553143956633 22513.119052395214 16454.193589606904 19375.994766189862 16099.63688630817 14904.143550678007 20891.884769748984 18916.088083548373 16835.641234128096 15688.740167661837 1.2039560182716493 1.434985780362404 1.0487899865613712 1.2350255380051687 1.0261905490342231 0.9499898265508235 1.3316483380107247 1.2057110947977108 1.073103452170767 1.0 13.937441885657819 -5.269288494863233 24.99653298175505 1.1199979166075271 1.3194709033204486 0.3161372156132012 0.12305817060347077 654.5156362370918 2084396.08910218 0.03239031793829792 0.06937483424981054 5.379123372631486e-06 5.269288494863233 0.19947298671292146 EGLRPGDTTST(ph)FCGTPNYIAPEILR ddPTM_PC-9_AZD4547_30min_R2 2 EGLRPGDTTSTFCGTPNYIAPEILR 25 1 P41743 P41743 PRKCI Protein kinase C iota type 1 EGLRPGDT(0.058)T(0.202)S(0.202)T(0.527)FCGT(0.01)PNYIAPEILR;EGLRPGDT(0.046)T(0.209)S(0.209)T(0.397)FCGT(0.133)PNY(0.007)IAPEILR 59.788999999999994 0.0025755 32648700.0 50602.0 48186.6 63296.0 62001.0 57318.0 55927.9 65143.0 45053.0 50903.9 37003.6 True False 66692.3834130148 63761.97610967845 62456.653683128265 47707.627355901066 49360.385080698295 52430.71957175104 70940.60080128726 38091.09406494669 53594.57623162849 35708.11522701927 1.867709426526961 1.78564384326372 1.7490884995203884 1.3360443992239088 1.382329612383147 1.4683138339398623 1.9866800683898493 1.0667349375002657 1.5009074517345309 1.0 15.123964366052721 -1.522878745355075 0.04879484530408114 3.322532965604463e-13 4.290491203415263 0.44263131251782306 0.23527049103147496 515.4928384690564 1.9081026030892143 40.29831859865261 168.2776967200852 0.029999999994837323 1.522878745355075 4.2904912034149305 EGLRPGDTTSTFCGT(ph)PNYIAPEILR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGLRPGDTTSTFCGTPNYIAPEILR 25 1 P41743 P41743 PRKCI Protein kinase C iota type 1 EGLRPGDT(0.053)T(0.2)S(0.2)T(0.2)FCGT(0.345)PNY(0.001)IAPEILR 53.355 0.0077 18603000.0 14314.0 14812.0 13791.0 17738.0 11497.0 13080.0 12041.0 18345.0 12521.0 9833.1 True False 16737.07748561319 16282.437470902249 14119.829742658754 16744.197367371904 9244.245381905066 12394.061773975984 10900.389310709224 17863.463188134185 12704.095937595232 11615.76319122323 1.440893483284816 1.4017535656378668 1.2155748623842104 1.4415064332599061 0.7958362468072643 1.0670036544254646 0.9384135274852593 1.5378639262921323 1.0936944674624856 1.0 13.503796326293756 -6.222725219483239 24.994618020982124 1.0920856457250887 1.3654652906150297 0.38005108897179285 0.188272230360533 684.6675597541332 442034.5892815638 0.05777751314522347 0.07458909550403145 5.987903331830029e-07 6.222725219483239 0.27337964488994104 EGLYLS(ph)DTLPR ddPTM_PC-9_AZD4547_30min_R2 1 EGLYLSDTLPR 11 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PRT1 E9PFQ4;A0A1W2PRT1 PHLDB2 Pleckstrin homology-like domain family B member 2 1 EGLYLS(0.996)DT(0.004)LPR 126.32 0.00041668 10123000.0 13768.0 11846.0 16544.0 20283.0 17886.0 18443.0 15913.0 14034.0 13217.0 16751.0 True False 18145.93760780974 15674.98783884422 16324.615750342424 15607.067719226172 15402.837634833213 17289.756294475646 17329.22617243426 11865.367769237604 13915.623636959714 16164.552588607588 1.1225759270688747 0.9697136838721783 1.009902109004096 0.9655118899007251 0.9528774489984205 1.0696093318822246 1.0720510869349709 0.7340362626306185 0.8608727993354502 1.0 13.980545955857869 -7.748697369264231 24.999999750229502 0.8480908726384393 1.017474581047223 0.4528394612279111 0.07886859528391699 178.44875301870593 350120.48760576925 0.036483515550848285 0.020886288759561715 1.783621220669875e-08 7.748697369264231 0.1693837084087837 EGLYLS(ph)DTLPR ddPTM_PC-9_Lapatinib_30min_R1 1 EGLYLSDTLPR 11 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PRT1 E9PFQ4;A0A1W2PRT1 PHLDB2 Pleckstrin homology-like domain family B member 2 1 EGLYLS(0.99)DT(0.01)LPR 121.21 0.00079051 8775300.0 13281.0 9981.1 10869.0 10708.0 11141.0 12760.0 10101.0 6554.1 13392.0 9149.2 True False 13091.61050456288 9957.989376186952 9975.392775553306 11495.502040840845 10485.708284048755 12214.284545012793 10623.980355427413 6858.627412918394 11883.651935988122 10730.627029457313 1.2200228811069738 0.9279969706197647 0.9296188142751801 1.071279619474596 0.977175728432624 1.1382638229324902 0.9900614685668286 0.6391637128091722 1.1074517736349954 1.0 13.389446760010907 -7.537516356394456 24.99920247752847 0.8869071810214136 1.0344779506126123 0.13387574844834538 0.13963405840823367 396.1984202592086 676648.5942888467 0.06205578564457207 0.03584604491090316 2.900571955323884e-08 7.537516356394456 0.14757076959119864 EGLYLSDT(ph)LPR ddPTM_PC-9_AZD4547_30min_R2 2 EGLYLSDTLPR 11 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PRT1 E9PFQ4;A0A1W2PRT1 PHLDB2 Pleckstrin homology-like domain family B member 2 1 EGLYLS(0.148)DT(0.852)LPR;EGLYLS(0.125)DT(0.875)LPR 112.84 0.0040027000000000005 18443900.0 24372.0 21269.4 28299.0 31801.0 30438.0 28618.0 26443.0 27235.0 24517.5 22257.0 True False 32121.789030907807 28144.317604213535 27923.73676976189 24469.77077055225 26212.209098124422 26828.511935981365 28796.375773121286 23026.45654803948 25813.444996531725 21477.78920450354 1.4955817251513202 1.310391741730668 1.3001215583169399 1.1393058446360644 1.220433297325972 1.2491281891506723 1.3407513920046836 1.0721055285900287 1.2018669496541603 1.0 14.390557878094015 -1.5228787452803376 0.10735708598801563 0.9299796030133393 2.327408323169258 0.602235728996229 0.08494288695443089 87.93908562390591 0.6642899510927881 0.8929394311239841 18.16531833853124 0.029999999999999995 1.5228787452803376 1.397428720155919 EGLYLSDT(ph)LPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 EGLYLSDTLPR 11 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PRT1 E9PFQ4;A0A1W2PRT1 PHLDB2 Pleckstrin homology-like domain family B member 2 1 EGLYLS(0.002)DT(0.998)LPR;EGLYLS(0.036)DT(0.964)LPR;EGLYLS(0.114)DT(0.886)LPR;EGLYLS(0.008)DT(0.992)LPR;EGLYLS(0.016)DT(0.984)LPR 123.26 0.0014392 32562700.0 70414.0 65237.0 75166.7 74267.8 70439.6 70314.7 61777.0 85003.3 74564.0 64345.0 True False 82333.69946010686 71713.29822368687 76958.95919929737 70106.81594545637 56637.46603489953 66627.27335004511 55925.03533325173 82772.05344344105 75654.35743877092 76010.23914526025 1.0831922170743613 0.9434689198469478 1.0124814770313255 0.9223338425692613 0.7451294282427114 0.8765565547388463 0.7357566028226217 1.088959255676838 0.9953179767556156 1.0 16.21390615296223 -4.711937636233463 1.0673578736584304 0.9035410584166553 1.1687986633052134 0.1652861935830433 0.10757720822937378 3.8021036784268696 3.2127323510941728 0.036641619671704664 1.1903373116511655 1.941164604700345e-05 4.711937636233463 0.2652576048885581 EGLYLSDT(ph)LPR ddPTM_PC-9_Lapatinib_30min_R1 2 EGLYLSDTLPR 11 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PRT1 E9PFQ4;A0A1W2PRT1 PHLDB2 Pleckstrin homology-like domain family B member 2 1 EGLYLS(0.031)DT(0.969)LPR;EGLYLS(0.051)DT(0.949)LPR 107.17 0.0057299 14746700.0 26588.0 23310.6 22251.0 21492.3 27729.0 18571.5 18081.699999999997 15123.9 28878.0 15215.1 True False 26208.850244357964 23256.625737898983 20421.608671343874 23072.91543821103 26098.034737311522 17777.24023728097 19017.88195156242 15826.611606511402 25625.455541178708 17845.009762153615 1.468693522373 1.3032565433067194 1.1443876435783638 1.2929617717074584 1.4624836346495724 0.9962023262651067 1.065725500016048 0.8868928522570545 1.4360012060921459 1.0 14.12323307016624 -6.771369051300868 24.995938038941606 1.0691927296973842 1.3197753027331196 0.39441833272868165 0.15880933306224315 222.07850187378887 559034.355930095 0.054817338779924014 0.048913655541141195 1.6928986111634217e-07 6.771369051300868 0.2505825730357354 EGMGS(ph)PAYEQDLIVASRPK ddPTM_PC-9_AZD4547_30min_R2 1 EGMGSPAYEQDLIVASRPK 19 1 Q96M11 Q96M11 HYLS1 Hydrolethalus syndrome protein 1 1 EGMGS(0.935)PAY(0.065)EQDLIVASRPK 87.102 0.0018210000000000001 6614200.0 21862.0 20906.0 30156.0 39955.0 31413.0 32690.0 27451.0 38535.0 24899.0 29760.0 True False 28813.661242151094 27663.455660887856 29756.111736419618 30743.992048596432 27051.84717784946 30645.889132267468 29894.08582036652 32580.301196207125 26215.110307684048 28718.11145823903 1.0033271611209884 0.9632755865968129 1.0361444477186468 1.0705436565110966 0.9419786261776789 1.067127592175821 1.040948875201545 1.1344862019769082 0.9128424181306363 1.0 14.80967325825716 EGMGSPAY(ph)EQDLIVASRPK ddPTM_PC-9_AZD4547_30min_R2 1 EGMGSPAYEQDLIVASRPK 19 1 Q96M11 Q96M11 HYLS1 Hydrolethalus syndrome protein 1 1 EGMGS(0.297)PAY(0.703)EQDLIVASRPK 74.732 0.0027125 4560800.0 20289.0 18766.0 21335.0 35970.0 32136.0 29738.0 21142.0 24364.0 23114.0 22145.0 True False 26740.479962583653 24831.74251086871 21052.083959958654 27677.672230960194 27674.47110773791 27878.478158928414 23023.597042519013 20599.10362902273 24335.758851833758 21369.710290413397 1.2513262743940718 1.1620065117124403 0.9851366103640051 1.2951823798648592 1.295032582643522 1.3045791346752555 1.0773939716369276 0.963939302362168 1.1387968541038644 1.0 14.383279729034443 -7.441330056106854 6.4687449422847845 1.0350025350860992 1.2093119413937168 0.42688215729214996 0.097551155696207 0.2590128485561206 16.948949398117737 0.04457528688583558 0.029660805903677524 3.6196780474433066e-08 7.441330056106854 0.1743094063076176 EGMNPS(ph)YDEYADSDEDQHDAYLER ddPTM_PC-9_AZD4547_30min_R2 1 EGMNPSYDEYADSDEDQHDAYLER 24 0 Q08945;A0A0U1RRK2 Q08945 SSRP1 FACT complex subunit SSRP1 1 EGMNPS(0.452)Y(0.288)DEY(0.162)ADS(0.098)DEDQHDAYLER 49.515 0.022073 3064300.0 2308.1 3427.4 3623.0 5629.4 5817.1 3414.5 2739.6 5740.2 4384.4 3116.5 True False 3042.027788537598 4535.240023539991 3574.956652773855 4331.628803363004 5009.496075455008 3200.990775225674 2983.419092691566 4853.1839866736245 4616.150433069998 3007.392283588774 1.0115167898573887 1.5080307442060767 1.1887230915242613 1.440327165498342 1.6657275150939368 1.0643742064157575 0.9920285787032079 1.6137515591688076 1.5349345871039695 1.0 11.55429734967265 -11.66106034197031 2.4445303026982286 0.26175210572123797 1.3391531045686866 0.14742648283801763 0.24189151000155162 21307196.051865365 9282674.69847983 86387827.57464859 0.06277260349390573 2.182426658913542e-12 11.66106034197031 1.0774009988474487 EGMNPSYDEY(ph)ADSDEDQHDAYLER ddPTM_PC-9_AZD4547_30min_R2 1 EGMNPSYDEYADSDEDQHDAYLER 24 0 Q08945;A0A0U1RRK2 Q08945 SSRP1 FACT complex subunit SSRP1 1 EGMNPS(0.009)Y(0.296)DEY(0.621)ADS(0.073)DEDQHDAYLER 61.04 0.0041313999999999995 3996000.0 3223.0 3236.6 2819.4 4424.3 4595.9 3364.2 3169.3 4846.2 3310.8 3561.0 True False 4247.846957435412 4282.7676548373465 2782.0129138367647 3404.3459897536054 3957.838616008609 3153.8360421772486 3451.3615602523637 4097.331144597353 3485.8021288678365 3436.330473884041 1.2361578694828277 1.2463200752623156 0.8095882904685504 0.9906922560639856 1.1517630932437979 0.9177918323474015 1.0043741678754585 1.1923565488642283 1.014396652289347 1.0 11.746653072624827 -5.2080843537052 24.82457089288488 1.017852322935956 1.2412394560922877 0.4519180500833937 0.10152411408228625 283.57460072086724 131937.8742650756 0.026446187298473044 0.06996993817915975 6.193207717392251e-06 5.2080843537052 0.22338713315633174 EGMNPSYDEYADS(ph)DEDQHDAYLER ddPTM_PC-9_AZD4547_30min_R2 12 EGMNPSYDEYADSDEDQHDAYLER 24 0 Q08945;A0A0U1RRK2 Q08945 SSRP1 FACT complex subunit SSRP1 1 EGMNPSYDEY(0.001)ADS(0.999)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPSY(0.001)DEY(0.011)ADS(0.987)DEDQHDAYLER;EGMNPSY(0.001)DEYADS(0.999)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPSY(0.004)DEY(0.065)ADS(0.931)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPSY(0.001)DEY(0.016)ADS(0.982)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPS(0.001)Y(0.006)DEY(0.025)ADS(0.969)DEDQHDAYLER 137.3 4.4491e-09 355783400.0 301144.8 315827.0 422446.9 490660.6 445662.5 431403.0 371455.0 471412.9 370162.4 402273.6 True False 396902.5821990371 417911.90141639835 416844.9780840992 377546.3793007026 383789.9545697108 404427.30221253005 404513.77539631457 398566.86829576886 389728.428762483 388190.12370655424 1.0224437922564689 1.0765650022881874 1.0738165466548708 0.9725811045777724 0.9886649121960412 1.0418279021396486 1.0420506620155539 1.0267310885968308 1.0039627619611766 1.0 18.566403888055547 -5.738304845237669 24.999728214872846 1.0136137300530839 1.0595041141819892 0.42097685469743595 0.024961474259095562 251.1084476646317 271351.60637072433 0.007282223788858831 0.012603511822261972 1.8268174641742106e-06 5.738304845237669 0.04589038412890534 EGMNPSYDEYADS(ph)DEDQHDAYLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EGMNPSYDEYADSDEDQHDAYLER 24 0 Q08945;A0A0U1RRK2 Q08945 SSRP1 FACT complex subunit SSRP1 1 EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPS(0.005)Y(0.011)DEY(0.055)ADS(0.901)DEDQHDAY(0.028)LER;EGMNPSYDEY(0.001)ADS(0.999)DEDQHDAYLER 140.73 6.1531e-08 91573300.0 113110.3 112504.4 134529.3 136923.0 157355.0 125011.6 154893.0 128779.0 133287.0 130757.6 True False 132257.6397597425 123673.09331632275 137736.98871721156 129251.64822035532 126522.41733231892 118455.77162565572 140220.4137117917 125398.68770262948 135236.0702207698 154462.9178034083 0.8562420135561118 0.8006652669459922 0.8917155695097995 0.8367810867386277 0.819111921045992 0.7668880875112016 0.9077933765970702 0.811836843987564 0.8755245086907568 1.0 17.236901003684054 -8.639509467710015 4.316691548902193 0.9999911268805124 0.8367187232497317 0.6081813634033291 0.03946712639162033 0.4950621779942011 17.363432997100926 0.036862503919321485 0.009627225244822695 2.2934566320711123e-09 8.639509467710015 -0.16327240363078066 EGMNPSYDEYADS(ph)DEDQHDAYLER ddPTM_PC-9_Lapatinib_30min_R1 15 EGMNPSYDEYADSDEDQHDAYLER 24 0 Q08945;A0A0U1RRK2 Q08945 SSRP1 FACT complex subunit SSRP1 1 EGMNPSYDEY(0.001)ADS(0.999)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPSY(0.001)DEY(0.011)ADS(0.988)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPSY(0.001)DEY(0.018)ADS(0.981)DEDQHDAYLER;EGMNPS(0.019)Y(0.014)DEY(0.065)ADS(0.894)DEDQHDAY(0.009)LER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPS(0.001)Y(0.002)DEY(0.029)ADS(0.969)DEDQHDAY(0.001)LER 137.42 2.524e-09 670687800.0 581214.2 608221.5 737129.8 579811.1 703963.2999999999 721100.5 617406.8999999999 631438.8 712792.7000000001 603201.7999999999 True False 572925.9789263682 606813.2004857664 676525.8332473151 622452.3424871289 662557.5627390988 690260.7125823663 649373.2082868373 660777.7518286709 632510.4800861122 707464.4274141226 0.8098300871755341 0.8577296284758091 0.9562683394840187 0.8798355342929053 0.9365242082359329 0.9756825726282264 0.9178881412601669 0.934008447949676 0.8940526980247231 1.0 19.432298082899415 -5.059380635068527 3.253886508946682 0.9330691178445514 0.8137470486476115 0.6045252443697238 0.034124624701627734 0.16331241293224225 3.2843785351564185 0.008602799468173631 0.034218679863748214 8.722065925068903e-06 5.059380635068527 -0.11932206919693988 EGNNPAENGDAK ddPTM_PC-9_AZD4547_30min_R2 1 EGNNPAENGDAK 12 0 P05204 P05204 HMGN2 Non-histone chromosomal protein HMG-17 0 120.96 0.0025821 0.0 7961.0 7465.8 8374.7 12180.0 10696.0 11105.0 7137.6 11237.0 12982.0 9945.1 False True 10492.432400913223 9878.97384832376 8263.646006068228 9372.089179124128 9211.0450263992 10410.602594488533 7772.832572636627 9500.579850571681 13668.202016721722 9596.925076052848 1.0933119012354207 1.0293894940343657 0.8610722643535538 0.9765720900031041 0.9597912824581144 1.0847852319349716 0.8099294837710187 0.9899608234181616 1.4242272299101206 1.0 13.228356514647402 -8.092645306258698 11.342786122926388 1.211420040858919 0.9698790465753181 0.3597434431521237 0.12630786655286183 0.6772385633838529 80.34907689002893 0.0801010457321661 0.030252577034112688 8.078945784996719e-09 8.092645306258698 -0.24154099428360098 EGNNPAENGDAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EGNNPAENGDAK 12 0 P05204 P05204 HMGN2 Non-histone chromosomal protein HMG-17 0 ;; 120.96 0.00216 5403000.0 40186.0 41922.0 41725.0 45795.0 55096.0 45551.0 49580.0 47229.0 34438.9 33295.6 False True 46988.69609032074 46083.73910715393 42719.8822429437 43229.254619393214 44300.33430994533 43162.22537204741 44883.4234718847 45989.288793261934 34942.503760502244 39331.828712175404 1.1946735666469306 1.1716653055821031 1.0861402493019476 1.0990908898678118 1.1263227711614612 1.0973866912698693 1.1411476389855926 1.1692639345555187 0.8884027238145066 1.0 15.26340964471797 -8.257893738259977 24.999381767064097 0.944201353198705 1.1326275590329051 0.7692185856296355 0.041931970732498915 132.79736031878682 936336.2463145809 0.03148728510311026 0.010825468725000847 5.522125362928065e-09 8.257893738259977 0.1884262058342001 EGNNPAENGDAK ddPTM_PC-9_Lapatinib_30min_R1 2 EGNNPAENGDAK 12 0 P05204 P05204 HMGN2 Non-histone chromosomal protein HMG-17 0 ; 125.36 0.0013607 10053300.0 27742.0 37857.0 36215.0 35262.0 38169.0 31154.0 40816.0 39133.0 34984.0 27531.0 False True 27346.393992740286 37769.344442427166 33237.54249394265 37855.285110583696 35923.974463141254 29821.61604352107 42929.252765778205 40951.262042040165 31043.733522148188 32289.696667248423 0.846907738853981 1.1697026711538228 1.0293544357651285 1.1723642219587795 1.1125522433160264 0.9235644531083274 1.3295031293781563 1.2682454859843018 0.9614129808049878 1.0 14.978786267738508 -4.75449429968447 24.870838717213516 1.116740092448526 0.8469072419500782 0.2776677538155625 0.12523836256580717 298.37249883652424 1068393.0929108968 0.030942870592231792 0.29991750858084226 1.759971764091612e-05 4.75449429968447 -0.26983285049844785 EGNTTEDDFPS(ph)SPGNGNK ddPTM_PC-9_AZD4547_30min_R2 1 EGNTTEDDFPSSPGNGNK 18 0 Q15007 Q15007 WTAP Pre-mRNA-splicing regulator WTAP 1 EGNTTEDDFPS(0.893)S(0.107)PGNGNK 212.41 2.6096999999999997e-21 4946800.0 16990.0 18644.0 22698.0 26370.0 26098.0 23271.0 24719.0 22891.0 21998.0 23396.0 True False 22392.466586046445 24670.30839670875 22397.009689390256 20290.803912438692 22474.743184271327 21815.860691251022 26918.943112951823 19353.721932850065 23160.769370192917 22576.913161188182 0.991830301431162 1.0927228279869239 0.992031529265604 0.8987412835214548 0.9954745816583777 0.9662906764754059 1.1923216836935882 0.857235078802576 1.025860763375236 1.0 14.462560626002423 -5.468293561071157 21.91996702732461 0.9888410661879226 1.0423020728175472 0.05349058856546085 0.08601140862853361 244.21606719933698 98067.3466892759 0.022161549236825104 0.046131589568977976 3.401781687576988e-06 5.468293561071157 0.05346100662962461 EGNTTEDDFPS(ph)SPGNGNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EGNTTEDDFPSSPGNGNK 18 0 Q15007 Q15007 WTAP Pre-mRNA-splicing regulator WTAP 1 EGNTTEDDFPS(0.758)S(0.242)PGNGNK;EGNTTEDDFPS(0.909)S(0.091)PGNGNK 286.57 8.331799999999997e-106 17488000.0 101342.0 118636.0 104900.0 117024.0 132576.0 118556.0 127797.0 115152.0 110085.0 97583.0 True False 118497.19900426253 130413.39804199 107401.21383546531 110467.52467692674 106598.68450477917 112338.71465408998 115691.14298984378 112129.38201362896 111694.78486464109 115274.02543339718 1.0279609700342045 1.1313337723018966 0.9317035076346787 0.9583036964450631 0.9247415808027765 0.974536234262044 1.003618486947761 0.9727202775478234 0.9689501554639115 1.0 16.814707943193824 -5.266895607692615 24.99992236835112 0.9656300736313073 1.0796473731705158 0.6495102024187537 0.033142955902218836 232.5433285101106 1065496.0762352722 0.008506796074418054 0.018555268600203526 5.408843208593752e-06 5.266895607692615 0.11401729953920858 EGNTTEDDFPS(ph)SPGNGNK ddPTM_PC-9_Lapatinib_30min_R1 1 EGNTTEDDFPSSPGNGNK 18 0 Q15007 Q15007 WTAP Pre-mRNA-splicing regulator WTAP 1 EGNTTEDDFPS(0.918)S(0.082)PGNGNK 226.65 5.7043e-35 69115000.0 153500.0 157040.0 158260.0 151380.0 177210.0 166750.0 147540.0 162910.0 170080.0 137060.0 True False 151311.06185154783 156676.38352850897 145248.4737012664 162512.99018887623 166786.8562082649 159618.49121323563 155178.8992812355 170479.3933321943 150923.7993782003 160750.63837902984 0.9412781397158456 0.9746548138682082 0.903563899751295 1.0109632647659599 1.0375501950729578 0.9929571218054839 0.9653392412373699 1.0605207858038193 0.9388690514705198 1.0 17.294464941286655 -5.782114928062126 24.99986820254755 1.0031236096102123 0.9433145289464617 0.3777440031187289 0.0357449083694626 235.21084901762734 284404.82782196294 0.009628399502955512 0.014299429641267316 1.651524694703071e-06 5.782114928062126 -0.05980908066375057 EGNTTEDDFPSS(ph)PGNGNK ddPTM_PC-9_AZD4547_30min_R2 3 EGNTTEDDFPSSPGNGNK 18 0 Q15007 Q15007 WTAP Pre-mRNA-splicing regulator WTAP 1 EGNTTEDDFPS(0.003)S(0.997)PGNGNK;EGNTTEDDFPS(0.004)S(0.996)PGNGNK;EGNTTEDDFPS(0.09)S(0.91)PGNGNK 255.72 3.4174999999999994e-65 147309000.0 203738.0 206872.0 221948.0 286056.0 266677.0 245321.0 225332.0 247986.0 222760.0 229816.0 True False 268522.44598634134 273739.3283975503 219004.82450175285 220110.20872114375 229653.50173009114 229981.03908892573 245386.11147407512 209665.4618513722 234534.63882644655 221770.21179054672 1.210813859166759 1.2343376785701337 0.98753039343532 0.9925147608598995 1.0355471092167685 1.0370240314606987 1.1064881504727637 0.9454176021141786 1.0575569952918444 1.0 17.75870606992674 -5.257576579825662 24.99144317978269 1.0215438832132786 1.2225757913719475 0.7892532552229228 0.04181368805903893 134.72176486414227 871610.4247829515 0.010666171353510211 0.02610143319135406 5.5261595571642315e-06 5.257576579825662 0.2010319081586689 EGNTTEDDFPSS(ph)PGNGNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EGNTTEDDFPSSPGNGNK 18 0 Q15007 Q15007 WTAP Pre-mRNA-splicing regulator WTAP 1 EGNTTEDDFPS(0.08)S(0.92)PGNGNK;EGNTTEDDFPS(0.084)S(0.916)PGNGNK 287.0 7.697799999999997e-106 116797000.0 229332.0 237318.0 208357.0 290450.0 291990.0 233257.0 276780.0 254228.0 239569.0 206047.0 True False 268153.378086533 260877.3626599774 213325.02107832234 274177.02815160464 234776.6555677528 221024.59229451948 250561.3946863301 247554.78437683173 243072.24340498023 243401.69003284565 1.1016906992319866 1.0717976634622937 0.876431963350523 1.1264384734329742 0.9645646073208081 0.9080651505118699 1.0294151805294298 1.0170627177790985 0.9986464899737509 1.0 17.89297965971746 -5.022522412405727 24.515109160402602 0.9918549779570499 1.094217514561033 0.26998296279501244 0.06435464438648657 648.3681993123657 705738.4440013658 0.015891991177567507 0.04281791347464522 9.494619995544056e-06 5.022522412405727 0.10236253660398298 EGNTTEDDFPSS(ph)PGNGNK ddPTM_PC-9_Lapatinib_30min_R1 3 EGNTTEDDFPSSPGNGNK 18 0 Q15007 Q15007 WTAP Pre-mRNA-splicing regulator WTAP 1 EGNTTEDDFPS(0.003)S(0.997)PGNGNK;EGNTTEDDFPS(0.065)S(0.935)PGNGNK;EGNTTEDDFPS(0.187)S(0.813)PGNGNK 250.1 7.1486e-54 87184000.0 281320.0 246104.0 266956.0 248874.0 276938.0 262730.0 210750.0 241603.0 262524.0 224099.0 True False 277308.32521223073 245534.16130858473 245007.9081599601 267177.0241793269 260649.051321057 251493.65035354302 221661.60379233008 252828.75739511487 232955.78261972414 262834.21355685266 1.0550693589677862 0.9341788421904753 0.9321766175124053 1.01652300346939 0.9916861575735345 0.9568527892550922 0.8433514069293088 0.9619324439298176 0.886322139980206 1.0 18.003793560279874 -7.009336488373795 23.35891597283408 0.9169253281489421 0.9810159864201073 0.2427702141948922 0.051685804064026404 262.1589055785953 655895.7690732041 0.018209648660932696 0.015187248355984078 9.787313772334398e-08 7.009336488373795 0.06409065827116522 EGPEEPGLAKQDS(ph)FR ddPTM_PC-9_AZD4547_30min_R2 2 EGPEEPGLAKQDSFR 15 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 EGPEEPGLAKQDS(1)FR;EGPEEPGLAKQDS(1)FR 73.688 0.0080649 29218000.0 75695.0 40507.0 87361.0 172565.0 138273.0 86246.0 65418.0 70019.0 61484.0 96372.0 True False 99764.43544619076 53600.09559244161 86202.53605933668 132782.80535267276 119076.18071571556 80853.02398597558 71240.07526854171 59199.17242655326 64733.918717926215 92998.04561335388 1.0727584089344053 0.5763572259925536 0.9269284692038581 1.4278021056993704 1.2804159477800579 0.8694056251690265 0.7660384129439396 0.6365636184729958 0.6960782701505597 1.0 16.504912777344856 -6.99222467126051 24.39130270054152 0.7548605727210543 1.0466848377901443 0.25765707615080413 0.22666669284391247 208.7560924032649 654865.2375895481 0.0891666708267625 0.07847946755687313 1.0180645818513615e-07 6.99222467126051 0.29182426506909 EGPEEPGLAKQDS(ph)FR ddPTM_PC-9_Lapatinib_30min_R1 2 EGPEEPGLAKQDSFR 15 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 EGPEEPGLAKQDS(1)FR;EGPEEPGLAKQDS(1)FR 89.913 0.0020688000000000004 27272000.0 240720.0 75878.0 98978.0 98199.0 76400.0 74274.0 42109.0 41074.0 91959.0 44610.0 True False 237287.28865735792 75702.30915293058 90840.41090612869 105420.88204226077 71906.30220817919 71097.4741611505 44289.19797908061 42982.44798800901 81601.60904880028 52320.779060911394 4.535239973799131 1.4468880340026782 1.7362205329621156 2.014895113077936 1.37433546477713 1.3588764433033278 0.8464934730333337 0.8215177365376998 1.5596405579855834 1.0 15.67509640239893 -3.2653976781381573 1.416305379482945 1.299233537455111 199.9999999999887 0.8593317108294445 0.3829648394527006 33.16577708614681 1.390961622857531 0.1176890525932165 20389.391811444846 0.0005427531115010896 3.2653976781381573 198.70076646253358 up EGPEPPEEVPPPT(ph)TPPVPK ddPTM_PC-9_AZD4547_30min_R2 4 EGPEPPEEVPPPTTPPVPK 19 0 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 EGPEPPEEVPPPT(0.984)T(0.016)PPVPK;EGPEPPEEVPPPT(0.996)T(0.004)PPVPK;EGPEPPEEVPPPT(0.975)T(0.025)PPVPK;EGPEPPEEVPPPT(0.873)T(0.127)PPVPK 180.1 1.2189e-08 77555000.0 195092.0 209027.0 233974.0 218742.0 229058.0 253024.0 223980.0 277061.0 234006.0 237262.0 True False 257127.19783431245 276590.89000422845 230871.35188410405 168314.411430211 197257.25052888456 237202.36928121245 243913.78609324602 234247.58867840574 246375.07942728265 228955.52959693252 1.1230442797646123 1.208055077294513 1.008367661137271 0.7351401895666032 0.8615526817637836 1.0360193951148424 1.0653325845531965 1.0231139168850374 1.0760826779812507 1.0 17.80470788297628 -5.355890443481065 5.4259450459660865 0.9673401990737145 1.16418098172327 0.36862618480058584 0.099826246913989 0.24041276129200137 10.761664720410854 0.02969219971743921 0.06371095353449882 4.406660133083443e-06 5.355890443481065 0.1968407826495555 EGPEPPEEVPPPT(ph)TPPVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EGPEPPEEVPPPTTPPVPK 19 0 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 EGPEPPEEVPPPT(0.993)T(0.007)PPVPK;EGPEPPEEVPPPT(0.998)T(0.002)PPVPK;EGPEPPEEVPPPT(0.983)T(0.017)PPVPK 138.2 0.00015478 50779000.0 147845.0 173603.0 165392.0 160826.0 192201.0 143191.0 190981.0 156928.0 147112.0 135761.0 True False 172872.23842814605 190837.15853774297 169335.57253265256 151815.4406249273 154540.59377642281 135681.81188665098 172889.8970972975 152808.80627895967 149263.23469143905 160373.3946165153 1.0779358935534038 1.1899552228976171 1.0558831964464406 0.9466373209094203 0.9636298723111781 0.8460369141096826 1.0780460032707524 0.952831401021073 0.9307231729325002 1.0 17.29107529803464 -5.572247397957085 3.680407010845547 0.9584120329389273 1.1336085663866005 0.5789008318282889 0.06021227406007933 0.1472438617008466 4.1211325767551035 0.01638335060388198 0.031572678635511095 2.6776425582155652e-06 5.572247397957085 0.17519653344767316 EGPEPPEEVPPPT(ph)TPPVPK ddPTM_PC-9_Lapatinib_30min_R1 4 EGPEPPEEVPPPTTPPVPK 19 0 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 EGPEPPEEVPPPT(0.978)T(0.022)PPVPK;EGPEPPEEVPPPT(0.813)T(0.187)PPVPK;EGPEPPEEVPPPT(0.998)T(0.002)PPVPK;EGPEPPEEVPPPT(0.986)T(0.014)PPVPK 139.78 8.523600000000001e-05 63040000.0 144454.0 223214.0 245473.0 214938.0 257520.0 280229.0 280003.0 275711.0 267982.0 244812.0 True False 142394.05947038106 222697.16169722745 225291.15749318237 230745.2575321487 242373.17990380005 268244.258915705 294500.1852747989 288521.53959249007 237799.04518443614 287127.4280085146 0.49592635735990526 0.7756039304284909 0.784638232076183 0.8036336310068787 0.8441310591080579 0.9342341857628119 1.0256776488314647 1.0048553758644547 0.8282003806943319 1.0 18.131331625817225 -4.198449887420432 0.466928284704428 0.9696843944638276 9.919304260070407e-14 0.7899845038781594 0.06832315324303456 3.834070228541059 0.4295122176530085 0.04627291351302826 2.294257548101483 6.332134230290832e-05 4.198449887420432 -0.9696843944637284 down EGPEPPEEVPPPTT(ph)PPVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGPEPPEEVPPPTTPPVPK 19 0 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 EGPEPPEEVPPPT(0.185)T(0.815)PPVPK 73.279 0.012234 11658000.0 30262.0 37955.0 32238.0 33875.0 47110.0 34624.0 38724.0 30665.0 31792.0 29128.0 True False 35384.75889825528 41722.92156414358 33006.676183295844 31977.09357423177 37879.13368196465 32808.25648793155 35055.78238251841 29860.076242253203 32256.89785544507 34408.67582287889 1.0283673536407167 1.2125698117217674 0.9592544727149647 0.9293322922054931 1.100859965578164 0.9534879126652355 1.0188064941228936 0.8678066077276577 0.9374640867172498 1.0 15.070484752283313 -5.2693279891052915 0.5706131114329521 0.9502543197279383 1.1650590183468637 0.24835696317656397 0.0807329051194596 3.1943762703571905 1.1629128606529229 0.04816512941271546 0.4229279965891269 5.378634223563369e-06 5.2693279891052915 0.21480469861892537 EGPEPPEEVPPPTT(ph)PPVPK ddPTM_PC-9_Lapatinib_30min_R1 1 EGPEPPEEVPPPTTPPVPK 19 0 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 EGPEPPEEVPPPT(0.116)T(0.884)PPVPK 73.153 0.010681999999999999 3090700.0 21360.0 34201.0 35723.0 27972.0 37833.0 39375.0 38526.0 37453.0 34238.0 31767.0 True False 21055.40248305574 34121.80968580317 32785.99283476775 30029.154191856596 35607.73732253986 37691.02303760809 40520.68777083424 39193.203108898626 30381.755897876472 37257.883623133195 0.565126100452538 0.9158279098981656 0.8799746428541401 0.8059812118048401 0.9557101439983895 1.0116254433251264 1.0875735235179915 1.051943892072383 0.8154450264859548 1.0 15.18525810608001 -4.109677204679839 0.669617872297333 0.9871805293134391 1.489938055760975e-20 0.5927363776252195 0.09287979776933579 5.441475812064197 0.9621088794101312 0.041309727420071135 5.0234543352130405 7.76824287395194e-05 4.109677204679839 -0.9871805293134391 EGPS(ph)CPSPGPFCR ddPTM_PC-9_AZD4547_30min_R2 2 EGPSCPSPGPFCR 13 0 Q4AC94 Q4AC94 C2CD3 C2 domain-containing protein 3 1 EGPS(0.975)CPS(0.025)PGPFCR;EGPS(0.984)CPS(0.016)PGPFCR 153.75 0.00015269 22705000.0 30280.7 31897.0 50927.0 59431.0 53117.0 48203.0 40538.0 63686.0 38442.0 45722.0 True False 39909.3327223129 42207.08147016837 50251.67470488935 45730.10114979689 45742.62141615987 45188.858789926206 44145.80346748817 53844.79205869075 40473.965639101574 44121.28669669369 0.9045369188044006 0.956614927400366 1.1389439988533936 1.0364634527583656 1.036747222052064 1.024196304622107 1.0005556676296188 1.2203812737565902 0.9173342091615511 1.0 15.429187244002573 -5.051399211583762 7.074358198058205 1.051535392828859 0.9166495056197367 0.27147039865142664 0.07795260137418043 0.24380810905739217 29.021626435384047 0.018676337188628888 0.05176808055750792 8.883841231700753e-06 5.051399211583762 -0.13488588720912242 EGPS(ph)CPSPGPFCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGPSCPSPGPFCR 13 0 Q4AC94 Q4AC94 C2CD3 C2 domain-containing protein 3 1 EGPS(0.912)CPS(0.088)PGPFCR 98.368 0.0027765999999999997 7759300.0 10128.0 10981.0 13526.0 15157.0 19758.0 11628.0 19220.0 12903.0 17266.0 12566.0 True False 11842.470362881819 12071.12110909922 13848.511137640658 14307.802429657017 15886.561733989756 11018.207210075892 17399.342459250183 12564.309921858567 17518.482585937174 14844.116327598738 0.7977888411493955 0.8131923007539451 0.9329293055924782 0.9638702711494799 1.0702261679567187 0.7422609043820566 1.1721373017604741 0.8464168324050741 1.1801633859043636 1.0 13.857603591584903 -3.145690999386545 0.374455055777494 1.0224922538383066 4.190624206060008e-12 0.2718160681671119 0.12526679144120628 27.00588380222626 1.134686711184495 0.09526495330317974 15.981693871722733 0.0007150048712524388 3.145690999386545 -1.022492253834116 EGPSCPS(ph)PGPFCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGPSCPSPGPFCR 13 0 Q4AC94 Q4AC94 C2CD3 C2 domain-containing protein 3 1 EGPS(0.018)CPS(0.982)PGPFCR 120.6 0.00021005 8494300.0 14283.0 13988.0 13256.0 21397.0 22272.0 16811.0 19949.0 18648.0 17047.0 16476.0 True False 16700.829797891092 15376.63619652853 13572.073313659954 20198.19546000996 17907.961480889764 15929.40156592587 18059.28630174723 18158.509759189234 17296.280125244477 19462.968376055753 0.8580823580044054 0.7900457884649077 0.6973280257885508 1.0377756912382758 0.9201043301761189 0.8184466653875345 0.9278793425963021 0.9329774065465098 0.8886763720236613 1.0 14.248444137707054 -1.5228787454675274 0.12016966512369703 1.0269527028439245 0.2936177060094091 0.2674346908346398 0.08178092663012891 133.08645949909038 1.1033252044773054 0.590293527089988 16.334782869542536 0.02999999998706938 1.5228787454675274 -0.7333349968345153 EGPSCPS(ph)PGPFCR ddPTM_PC-9_Lapatinib_30min_R1 1 EGPSCPSPGPFCR 13 0 Q4AC94 Q4AC94 C2CD3 C2 domain-containing protein 3 1 EGPS(0.312)CPS(0.688)PGPFCR 99.669 0.0024486 7514500.0 11614.0 11229.0 18608.0 15589.0 20848.0 16327.0 13547.0 15612.0 19485.0 19028.0 True False 11448.382230253243 11202.999940407708 17078.122068957204 16735.46706337952 19621.761628745026 15628.73227009593 14248.397374019925 16337.39051440807 17290.394113853697 22316.964446783742 0.5129901182373013 0.5019947926664485 0.7652529137500353 0.7498988988079599 0.8792307607754808 0.7003072620993622 0.6384558889268367 0.7320615020634031 0.7747646036307388 1.0 14.445853184700448 -6.6111509284160865 0.06492429150825481 1.4119586986558654 1.114513858281669e-19 0.5572592656203557 0.09572230626988583 58.69465677377965 1.38009978039966 11.932295462884554 17.665718239080412 2.448212277740122e-07 6.6111509284160865 -1.4119586986558654 EGPVGGES(ph)DSEEMFEK ddPTM_PC-9_Lapatinib_30min_R1 1 EGPVGGESDSEEMFEK 16 0 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;J3QL92 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 EGPVGGES(0.558)DS(0.442)EEMFEK 68.972 0.019642 1659500.0 8211.6 10442.0 8955.4 7090.6 8662.1 8215.0 8333.1 7984.6 8938.5 9613.8 True False 8094.501078176985 10417.822190554569 8219.121580843686 7612.066377548199 8152.612308343835 7863.663600100328 8764.547143828553 8355.593665215385 7931.752003422183 11275.532520416726 0.7178819327176066 0.9239317231085014 0.7289342269166654 0.6750959534518614 0.7230356786769773 0.6974095091173308 0.7773067150450318 0.7410376095395782 0.7034481066911985 1.0 13.460907950185078 -10.533614733281613 4.854239049918165 1.0000034933590627 0.745029287759731 0.5774654173477255 0.06590212825021913 2.9855416680753038e-06 6.084527227382956e-07 0.06642357096017083 0.016109828352284035 2.926747571852619e-11 10.533614733281613 -0.2549742055993317 EGPVGGESDS(ph)EEMFEK ddPTM_PC-9_AZD4547_30min_R2 1 EGPVGGESDSEEMFEK 16 0 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;J3QL92 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 EGPVGGES(0.347)DS(0.653)EEMFEK 82.55 0.037147 0.0 10146.0 11924.0 12241.0 13620.0 14780.0 14957.0 11885.0 15818.0 11837.0 16154.0 True False 13372.216950089889 15778.199813471094 12078.67634187268 10480.119426902354 12728.05212137061 14021.73642555291 12942.741975704208 13373.691561479294 12462.679654285554 15588.45337689492 0.8578283314437134 1.0121722426201316 0.7748476420230115 0.672300142516762 0.8165051280992396 0.899495035622701 0.8302774921139923 0.8579229278320627 0.7994814721489713 1.0 13.928190176336225 -11.002646875521545 2.693457409322883 1.0064869897714166 0.8360591704341476 0.26246353913955023 0.08264952101261948 22307480.239873905 23178158.463753518 1080950.0436503491 0.022393365504687058 9.939238786242709e-12 11.002646875521545 -0.17042781933726903 EGPVLAT(ph)SSGAGVFK ddPTM_PC-9_AZD4547_30min_R2 1 EGPVLATSSGAGVFK 15 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 EGPVLAT(0.531)S(0.397)S(0.072)GAGVFK 173.36 0.0001898 7613300.0 30416.0 26245.0 32535.0 61822.0 53979.0 52210.0 66341.0 99592.0 76285.0 77183.0 True False 40087.65530789809 34728.183001052406 32103.56464200865 47569.89304037863 46484.947595362944 48945.30044648773 72245.22048045385 84202.34479648789 80317.26936108588 74480.84666267692 0.5382277069090623 0.46626998157440436 0.4310311453279445 0.6386862552170257 0.6241194841123766 0.6571528472032622 0.9699838779713635 1.1305234643456665 1.0783613903429705 1.0 16.184581852407256 -7.18639892506831 1.489304856716363 1.092790597113104 0.5201173965603472 0.9305288995846115 0.06601681124614776 0.10065792199419842 0.43950682541358066 0.03953482867881521 0.025039794121629586 6.510301098116103e-08 7.18639892506831 -0.5726732005527568 EGPVLAT(ph)SSGAGVFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGPVLATSSGAGVFK 15 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 EGPVLAT(0.373)S(0.373)S(0.253)GAGVFK 172.43 0.00024303 5535800.0 25341.0 19304.0 30572.0 30529.0 50431.0 46769.0 44123.0 43140.0 37717.0 39955.0 True False 29630.73079243564 21220.37354430846 31300.952424955656 28818.55910635342 40549.40757196263 44316.351307880934 39943.35001714338 42007.620710608295 38268.53977144633 47198.52521639402 0.6277893357172875 0.44959823314432157 0.663176492940155 0.6105817708122696 0.859124461750727 0.938935085465086 0.8462838581081212 0.8900197732453152 0.8107994814667233 1.0 15.526454160826496 -6.235197169305397 2.8097432148834662 0.890289375909374 0.5723428266095277 0.8183692149461081 0.07015524976051594 0.10959414100544942 1.729519651493218 0.021896477218585137 0.028003724640445506 5.818390034129947e-07 6.235197169305397 -0.3179465492998462 EGPVLAT(ph)SSGAGVFK ddPTM_PC-9_Lapatinib_30min_R1 1 EGPVLATSSGAGVFK 15 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 EGPVLAT(0.424)S(0.424)S(0.152)GAGVFK 184.0 1.2432e-06 8761200.0 70570.0 61451.0 63874.0 56981.0 48373.0 36614.0 43768.0 31666.0 50808.0 76155.0 True False 69563.65885904705 61308.713985038215 58622.52628077021 61171.572823043745 45527.79524497711 35048.10457140272 46034.09288153126 33137.31796241645 45085.468008041 89318.29027984107 0.7788288226420228 0.6864071602014918 0.6563328305669682 0.6848717393871794 0.5097253328779026 0.39239560521808375 0.5153937982612845 0.371002600459488 0.5047730746612454 1.0 16.446668015076135 -6.247559557188721 5.272076635608109 0.5073574270237563 0.6988143977733738 0.13920189399104932 0.1682205480262855 0.2664260830741455 24.44464683577774 0.04798614664816327 0.05958258596270165 5.65510200250179e-07 6.247559557188721 0.19145697074961754 EGPVLATSS(ph)GAGVFK ddPTM_PC-9_AZD4547_30min_R2 1 EGPVLATSSGAGVFK 15 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 EGPVLAT(0.301)S(0.301)S(0.398)GAGVFK 66.78399999999999 0.031163999999999997 7183600.0 25745.0 30497.0 36247.0 56788.0 56948.0 61037.0 61336.0 97277.0 83410.0 91979.0 True False 33931.3744707337 40354.55884866052 35766.34109663093 43696.40396585395 49041.75319403342 57220.346741089306 66794.78517642347 82245.07485307999 87818.88231511001 88758.8432062286 0.3822872543741375 0.4546539521126686 0.4029608747100148 0.4923047933863516 0.5525280797101685 0.6446720650486565 0.7525423131217215 0.9266127394426034 0.9894099465792425 1.0 16.437603244566205 -7.26547159344537 0.7739899658242212 1.0281046163816254 0.41138286106547756 0.9858559545764506 0.02735423735084276 0.06845752252655035 0.08041195053411142 0.0224836142383596 0.013834080467939953 5.4266074479855164e-08 7.26547159344537 -0.6167217553161479 down EGPVLATSS(ph)GAGVFK ddPTM_PC-9_Lapatinib_30min_R1 1 EGPVLATSSGAGVFK 15 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 EGPVLAT(0.3)S(0.3)S(0.399)GAGVFK 73.758 0.01695 8290200.0 70331.0 50226.0 64802.0 51238.0 49214.0 42193.0 36663.0 41814.0 56148.0 79704.0 True False 69328.06704287416 50109.704782876215 59474.22970295386 55006.21344495735 46319.329278446756 40388.503746686925 38561.23074656328 43756.831089511834 49824.02097534805 93480.73020109563 0.7416294983333539 0.5360431468076926 0.6362191392280845 0.5884230185903346 0.4954960148343372 0.4320516502150039 0.4125045949428337 0.46808396763035753 0.5329870751775974 1.0 16.512381382961856 -10.569111995956192 4.327771936514224 1.000034839342215 0.5323275249465527 0.6861712362204115 0.09362601627877655 11579286.99230396 5655695.3742182935 3588.890658828605 0.024520430052402353 2.6970438285038334e-11 10.569111995956192 -0.46770731439566227 EGPYSISVLYGDEEVPR ddPTM_PC-9_AZD4547_30min_R2 1 EGPYSISVLYGDEEVPR 17 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 185.32 1.4958e-07 4218200.0 11186.0 9782.3 10499.0 14291.0 16085.0 11301.0 10238.0 12321.0 9347.2 11821.0 False True 14742.915316746048 12944.23717169727 10359.776400075265 10996.430743749013 13851.87539731031 10594.346683504265 11149.162166365986 10417.072558413605 9841.273909312991 11407.150388032369 1.2924275402043743 1.1347476566345187 0.9081826790803127 0.96399454462227 1.2143151379719501 0.9287461217850829 0.9773836398319911 0.9132055074282629 0.8627285145322365 1.0 13.477650817581873 -4.981181828022518 3.163540593573836 0.9755886126356366 1.2892506994170214 0.561005641848309 0.09071667066812623 0.20541720302432684 3.967910364324811 0.024812810941629546 0.12665433987710142 1.0442829130623557e-05 4.981181828022518 0.31366208678138485 EGPYSISVLYGDEEVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGPYSISVLYGDEEVPR 17 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 139.74 0.00037951 2628100.0 5578.0 8165.6 5376.0 9307.3 8223.4 6027.2 5557.4 7018.9 4776.2 4280.4 False True 6522.245229478156 8976.226803429618 5504.184228593534 8785.842155673723 6612.083802170836 5711.123021720799 5030.96283990827 6834.661312139282 4846.042889317337 5056.402636372241 1.2898983127968613 1.7752199436929506 1.0885573448997639 1.7375677507314171 1.3076656029344078 1.1294834356423586 0.9949687953485004 1.3516845480174948 0.9583973504123815 1.0 12.303895633139403 -6.613235535316252 3.7143476722308466 1.1032630303154989 1.4726498381389057 0.42158247252908587 0.212435952615306 0.2258973079645485 6.0570536789868825 0.06811130718444082 0.06842051547137405 2.436489054241297e-07 6.613235535316252 0.3693868078234068 EGPYSISVLYGDEEVPR ddPTM_PC-9_Lapatinib_30min_R1 3 EGPYSISVLYGDEEVPR 17 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ;; 116.9 0.0006148 33277300.0 28889.0 44480.8 37826.0 37185.0 36264.0 37467.0 44212.0 36285.8 26419.7 31816.0 False True 28477.037562406225 44377.80744049219 34716.092292582514 39919.708945523635 34131.022817767174 35864.623749842816 46501.08102902257 37971.77073582555 23444.035174225333 37315.3532078448 0.76314533065761 1.1892640327778716 0.9303433924158638 1.069793141798034 0.9146643374285901 0.9611224513963064 1.246164836495415 1.0175910844076577 0.6282678082569161 1.0 15.187481721543204 -8.158805612891094 13.262014650492706 0.8142046538198983 1.0196942700610434 0.20483206683265298 0.15489009441499485 1.238214940665522 154.4998029022614 0.0983918577452673 0.037178869284259675 6.937362479263619e-09 8.158805612891094 0.20548961624114515 EGPYSISVLYGDEEVPRS(ph)PFK ddPTM_PC-9_AZD4547_30min_R2 2 EGPYSISVLYGDEEVPRSPFK 21 1 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 EGPYSIS(0.002)VLY(0.001)GDEEVPRS(0.996)PFK;EGPYSISVLYGDEEVPRS(1)PFK 80.585 0.00040315 31215000.0 35435.0 37765.0 44757.0 49920.0 54079.0 57844.0 42842.0 53132.0 43018.0 43171.0 True False 46702.592906212805 49971.79771517409 44163.49293629573 38411.715256311705 46571.064321488586 54227.00553584823 46654.855004048775 44921.670251897674 45291.843657012396 41659.59643022974 1.1210524562912876 1.1995266876592379 1.060103714884983 0.9220376227273951 1.117895234522601 1.3016690074438433 1.1199065521958413 1.0783030586273479 1.0871887281209225 1.0 15.346361243149653 -8.670270337802885 1.472836256222953 1.0012130351366217 1.1174790236756593 0.12876089984006056 0.09127647877716559 1.4757634800475405 6.497863513188922 0.0958335253115184 0.028115023052111887 2.136631673969592e-09 8.670270337802885 0.11626598853903758 EGPYSISVLYGDEEVPRS(ph)PFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EGPYSISVLYGDEEVPRSPFK 21 1 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 EGPYSISVLY(0.002)GDEEVPRS(0.997)PFK;EGPYSISVLYGDEEVPRS(1)PFK 110.13 1.8157999999999998e-05 22562000.0 59084.0 58333.0 53246.0 63766.0 66731.0 56649.0 62141.0 57818.0 50087.0 45683.0 True False 69085.75423780699 64123.914730633354 54515.58657657948 60193.39775216128 53655.53958249169 53678.226715134966 56254.554618119975 56300.338763234795 50819.4276197055 53964.966273571 1.2801963756927484 1.1882508071173878 1.0102032918952855 1.115416202560301 0.994266156129688 0.9946865609628581 1.0424273098391665 1.0432757148003171 0.9417114681788283 1.0 15.71973550190089 -3.948813052468917 0.6907306847843607 1.0059791398112234 1.9983120458612893 0.8063819930056189 0.04339100553972986 3.455591691606189 0.536209127919447 0.017313501744267965 3.4997037804595936 0.00011250891785545234 3.948813052468917 0.9923329060500659 EGPYSISVLYGDEEVPRS(ph)PFK ddPTM_PC-9_Lapatinib_30min_R1 1 EGPYSISVLYGDEEVPRSPFK 21 1 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 EGPYSISVLYGDEEVPRS(1)PFK 99.413 0.00010853 11797000.0 22123.0 20850.0 25027.0 23921.0 18718.0 23474.0 20480.0 18622.0 23544.0 14805.0 True False 21807.521963138683 20801.723106020178 22969.376667013745 25680.23013811673 17617.04404100391 22470.07174056664 21540.35419059038 19487.246102953308 20892.22679068881 17364.024523577533 1.2559025088640943 1.197978215117976 1.3228141112001455 1.4789330724134337 1.0145714789266058 1.2940589729101064 1.2405162271766013 1.1222770433486076 1.2031903526927499 1.0 14.08381374480291 -8.845928064374872 0.36894005722620143 0.9737860100340592 1.2878766168251825 0.3373778355901442 0.11079092863426471 2.5566656645756742 0.7759344810167081 0.25470861044856574 0.10106929480063145 1.425843747804974e-09 8.845928064374872 0.31409060679112333 EGQEDQGLTK ddPTM_PC-9_Lapatinib_30min_R1 1 EGQEDQGLTK 10 0 A6NLN1;P26599;P26599-2;P26599-3;A0A0D9SF20;A0A087WUW5;O95758-7;O95758-1;O95758-6;O95758-2;O95758;O95758-5;O95758-4;A0A0U1RRM4 A6NLN1;O95758-1;A0A0U1RRM4 PTBP1;PTBP3 Polypyrimidine tract-binding protein 1;Polypyrimidine tract-binding protein 3 0 113.22 0.0061641000000000005 15499000.0 47008.0 52307.0 53885.0 47986.0 49111.0 56923.0 64289.0 56164.0 52894.0 45263.0 False True 46337.6572997886 52185.88635523253 49454.78330211516 51515.05051660339 46222.38753594097 54488.53598399403 67617.56985150713 58773.584476762386 46936.520721487126 53086.64924084362 0.8728683758050697 0.983032214342169 0.9315860769013429 0.9703955938693701 0.870697024523796 1.026407519841577 1.2737208096284172 1.1071255262338797 0.8841492426569517 1.0 15.696061462880058 -6.984305149802423 12.534131569818511 1.0858656809613345 0.9333608169748594 0.31291920002112417 0.09758693653759508 0.8923105885078295 707.9330423726743 0.03510152829336346 0.0307603062188917 1.036799669764574e-07 6.984305149802423 -0.15250486398647511 EGQGGAGRT(ph)SPGGR ddPTM_PC-9_AZD4547_30min_R2 1 EGQGGAGRTSPGGR 14 1 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 EGQGGAGRT(0.5)S(0.5)PGGR 61.532 0.037257 12589000.0 28987.0 14719.0 34439.0 77187.0 56478.0 35218.0 21455.0 32483.0 22590.0 42358.0 True False 38204.263032944575 19476.62890426711 33982.31635795714 59392.729677262316 48637.00458124285 33015.8128926337 23364.453436157673 27463.498735082296 23784.06128160095 40875.05931277175 0.9346595130446046 0.47649175883107464 0.8313704476347777 1.4530310334914809 1.189894409915775 0.8077251372285504 0.5716065940693879 0.6718889023483594 0.5818722145357088 1.0 15.31893320362022 -6.99560707313055 24.513666985210936 0.6805231000703497 0.970742744482501 0.19504588317532923 0.2587228171708064 171.43536263692422 956642.5073228794 0.10125971594072085 0.08893349750333356 1.010166418350674e-07 6.99560707313055 0.2902196444121513 EGQGGAGRTS(ph)PGGR ddPTM_PC-9_Lapatinib_30min_R1 1 EGQGGAGRTSPGGR 14 1 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 EGQGGAGRT(0.132)S(0.868)PGGR 51.126999999999995 0.046205 12622000.0 48497.0 15330.0 17213.0 14863.0 13192.0 11803.0 7071.8 6927.7 16362.0 8416.0 True False 47805.42388673943 15294.504326872386 15797.81358410149 15956.074601514534 12416.072496469902 11298.213204136833 7437.94320141685 7249.586232812244 14519.139260501626 9870.6943863849 4.843167260114916 1.549486158539038 1.6004764169268717 1.616509839826819 1.2578722438814396 1.1446219244434288 0.7535379893512199 0.7344555457832764 1.4709339274578839 1.0 13.268935864030295 -3.162888315275185 1.265757602203415 1.1352644047616713 199.99999999999676 0.9231194004916701 0.312319020567503 21.163877621077386 0.8156021021786155 0.09780487451519647 11564.50768911802 0.0006872451517166042 3.162888315275185 198.8647355952351 up EGQHYPER ddPTM_PC-9_AZD4547_30min_R2 2 EGQHYPER 8 0 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 0 ; 104.01 0.0032438000000000002 8518700.0 61214.0 49523.0 76336.0 101109.0 89558.0 74123.0 63478.0 87117.0 59714.0 72013.0 False True 80678.77866970262 65530.34127495207 75323.73476294361 77799.88216847791 77124.41758360689 69488.07709241558 69127.41902681976 73655.06939950651 62870.360131452886 69491.84678905144 1.1609819338175036 0.9429932330604932 1.0839219022570428 1.1195541025790583 1.1098340474059465 0.9999457533968366 0.99475581986851 1.05990951173154 0.9047156326453856 1.0 16.08455610145745 -6.7800629781677095 22.19778391518787 0.9957901915952301 1.0776846647641467 0.3393927657605881 0.06351982173958981 88.29595891269095 105239.28616287372 0.022160740249900404 0.019597806101040907 1.6593462638901246e-07 6.7800629781677095 0.08189447316891663 EGQHYPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGQHYPER 8 0 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 0 84.615 0.011618999999999999 2778200.0 17652.0 18924.0 22681.0 23477.0 21394.0 20036.0 21062.0 19866.0 17000.0 17225.0 False True 20640.13495710801 20802.64965564098 23221.801058171488 22161.65980346096 17201.999278114017 18985.27688863782 19066.85488432503 19344.53854976691 17248.59283915973 20347.756146975033 1.014369093477486 1.0223559544050056 1.1412462824125067 1.0891451442303426 0.8454003062480836 0.9330403191145102 0.937049507896701 0.9506964016099994 0.8476901686146836 1.0 14.312582089317814 -6.248812488935948 24.99245906386687 0.9181208164789182 1.068925127986078 0.64076915513373 0.05420263755397684 495.47434336849466 980694.0198764555 0.016172406384565102 0.020727504150789045 5.638810646655133e-07 6.248812488935948 0.1508043115071599 EGQHYPER ddPTM_PC-9_Lapatinib_30min_R1 2 EGQHYPER 8 0 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 0 ; 97.565 0.004846100000000001 7740200.0 100488.0 81785.0 93313.0 76025.0 85656.0 89301.0 78999.0 76458.0 91070.0 74207.0 False True 99055.02269275788 81595.63185735537 85641.16533859652 81616.13211196547 80617.8824861753 85481.8044007984 83089.18167492432 80010.51780365176 80812.73759038528 87033.58107538804 1.1381241753910705 0.9375189535942186 0.9840013967070318 0.9377544977871243 0.926284791342143 0.9821703685472221 0.9546795690614281 0.9193062817252925 0.9285236410114587 1.0 16.409284538019705 -4.759038429568704 24.99999999985055 0.9504660977469671 1.1381244202237495 0.816806640872143 0.026396016575761443 25.388695246249096 264303.8554835188 0.006453239225895164 0.04211556833555383 1.7416527523326278e-05 4.759038429568704 0.18765832247678238 EGQSPASQAGTQHPPAQATAHS(ph)QSSPEFK ddPTM_PC-9_Lapatinib_30min_R1 2 EGQSPASQAGTQHPPAQATAHSQSSPEFK 29 0 H0YJ83;A0A087WWY9;Q8TB24-4;Q8TB24 H0YJ83 RIN3 Ras and Rab interactor 3 1 EGQSPASQAGTQHPPAQAT(0.04)AHS(0.32)QS(0.32)S(0.32)PEFK;EGQSPASQAGTQHPPAQAT(0.006)AHS(0.331)QS(0.331)S(0.331)PEFK 60.481 0.00098982 9953100.0 23590.0 16344.9 19412.2 12336.900000000001 22447.6 22892.0 18141.9 17174.8 23268.0 12347.2 True False 23253.60227412381 16307.054388277658 17816.20384925899 13244.196780691957 21127.276301679623 21912.962523858394 19081.19881300154 17972.80390768997 20647.312817097652 14481.39706839016 1.6057568316306665 1.1260691431403758 1.2302821174724923 0.9145662340549482 1.4589252819947889 1.5131801455599734 1.3176352200611763 1.24109599528355 1.4257818302742618 1.0 13.821913170258693 -10.584597092823891 4.6248823090065825 0.9999861330523335 1.3029891922403627 0.19340292097624212 0.19150646654488707 138451345.90371284 8.080566450930483 20445.656885911972 0.04727358106358698 2.6025729234441025e-11 10.584597092823891 0.30300305918802917 EGRGES(ph)ENAGTNQETR ddPTM_PC-9_AZD4547_30min_R2 1 EGRGESENAGTNQETR 16 1 Q08170 Q08170 SRSF4 Serine/arginine-rich splicing factor 4 1 EGRGES(1)ENAGTNQETR 103.45 0.00064284 30894000.0 4014.8 3635.6 4128.1 8343.4 5821.4 4729.2 3760.3 5220.7 4359.2 5634.2 True False 5291.422886972292 4810.736601967083 4073.3586967473752 6419.958034245015 5013.199094678411 4433.482376393983 4094.959415333658 4413.96077475123 4589.6184125168165 5436.94837291701 0.9732339768628995 0.8848229322777339 0.7491994437611246 1.1808017280842056 0.9220611914673652 0.8154358055850637 0.753172392758375 0.8118452617167431 0.8441533922556658 1.0 12.408581413609168 -6.708746406220141 5.990856914826312 0.8274412197116704 0.9425187043639935 0.14189785541579036 0.11601220048651764 0.35453760107077986 27.41129118151417 0.03931617450202403 0.038798042355636386 1.95548096937196e-07 6.708746406220141 0.11507748465232315 EGRGES(ph)ENAGTNQETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGRGESENAGTNQETR 16 1 Q08170 Q08170 SRSF4 Serine/arginine-rich splicing factor 4 1 EGRGES(0.922)ENAGT(0.073)NQET(0.005)R 76.329 0.0054551 25634000.0 4745.2 3963.7 6683.6 6778.9 7108.5 6743.1 5751.6 6882.6 6202.7 6082.1 True False 5548.468638027921 4357.189940819287 6842.962371694152 6399.100210490332 5715.640453794216 6389.47996545088 5206.7668100220235 6701.939042717491 6293.402753144474 7184.736584122894 0.7722577679868097 0.606450896258044 0.9524305159379111 0.8906520281663921 0.7955254012269367 0.8893130444852491 0.7246983586744344 0.9328023323120422 0.875940638805308 1.0 12.810719548408574 -1.5228787808634103 0.060584252760938616 1.2109182118756967 0.06317305286155683 0.3252922814620389 0.09270908373646865 424.7719435028345 1.9288246817793948 7.350814154255445 42.95084285201388 0.02999999754200851 1.5228787808634103 -1.1477451590141399 EGRGES(ph)ENAGTNQETR ddPTM_PC-9_Lapatinib_30min_R1 1 EGRGESENAGTNQETR 16 1 Q08170 Q08170 SRSF4 Serine/arginine-rich splicing factor 4 1 EGRGES(0.792)ENAGT(0.208)NQETR 87.15700000000001 0.020802 13820000.0 5169.0 4174.5 6778.0 6087.8 5549.9 4655.8 5034.9 4424.7 5194.1 4281.0 True False 5095.2891121214925 4164.834201730513 6220.739003836626 6535.51712030547 5223.465793523214 4456.682287199891 5295.582486045092 4630.287715161499 4609.085761702205 5020.965145926062 1.014802724981219 0.8294887697258362 1.238952835369519 1.3016455861296494 1.040331020373933 0.8876146632517412 1.0546941339240028 0.9221907702184404 0.9179680853674018 1.0 12.293748994934912 -6.529402283201428 23.537848678211613 0.9584573563688694 1.0978179830029215 0.21557231487511208 0.1262210284439682 141.47148329523628 510439.7775883465 0.04544254700050432 0.045578732856307425 2.955273753948949e-07 6.529402283201428 0.13936062663405213 EGRPGEWR ddPTM_PC-9_AZD4547_30min_R2 2 EGRPGEWR 8 1 Q86WR7;Q86WR7-2;D3DRR9 Q86WR7 PROSER2;C10orf47 Proline and serine-rich protein 2 0 ; 81.191 0.023635 3045200.0 15679.9 10567.5 20527.6 29128.0 21850.2 20457.0 18037.4 23118.0 18768.6 22138.0 False True 20665.782037819277 13983.237716274389 20255.390611504434 22412.989623113943 18816.676891906107 19177.820556096536 19642.69365692614 19545.644298791147 19760.669879143683 21362.95535828276 0.967365314921506 0.6545553965618742 0.9481548911092534 1.0491521068700855 0.8808086978757168 0.8977138338053487 0.9194745449538354 0.9149316642284228 0.9249970122454126 1.0 14.382823623288656 -1.5228787452803376 0.23518791942007722 0.9579573127870333 0.26823569955676174 0.08086131556685683 0.09513898125647087 123.50881982014559 1.634511683270051 0.13686860199076262 33.02998282541637 0.029999999999999995 1.5228787452803376 -0.6897216132302716 EGRPGEWR ddPTM_PC-9_Lapatinib_30min_R1 1 EGRPGEWR 8 1 Q86WR7;Q86WR7-2;D3DRR9 Q86WR7 PROSER2;C10orf47 Proline and serine-rich protein 2 0 87.181 0.015449000000000001 1665800.0 7832.4 7008.1 7101.7 7719.9 8293.8 6468.1 6724.0 6913.4 7444.4 7689.7 False True 7720.708539713755 6991.873175026379 6517.825639354761 8287.647198831462 7805.974990238179 6191.474440877532 7072.135819215322 7234.621802607525 6605.93327899268 9018.85439911882 0.8560631093532346 0.7752506987705128 0.722688863897346 0.9189246030672367 0.8655173534014315 0.686503425699218 0.7841501266398424 0.8021663819425201 0.7324581356627853 1.0 13.138728474498134 -11.346228141612496 6.993483580840235 1.0119966742317916 0.7937167514329556 0.456866624372091 0.06746524186214763 0.013205286057061612 0.0003335561152171095 0.06835608383478459 0.016251258989791205 4.505799457416894e-12 11.346228141612496 -0.218279922798836 EGRPPEPT(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 1 EGRPPEPTPAK 11 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 EGRPPEPT(1)PAK 66.215 0.030819 46210000.0 148450.0 121200.0 167890.0 228220.0 224400.0 197980.0 189650.0 161480.0 182750.0 212130.0 True False 195654.01204818106 160375.52980482206 165663.66890262265 175607.40496385138 193245.93342595187 185600.27930273168 206528.48259926846 136526.97644124902 192409.79190848052 204703.39326734724 0.9557927151341967 0.7834532063441079 0.8092863838669355 0.8578626966603536 0.9440289696300653 0.9066790556829389 1.0089157746864392 0.6669502359589209 0.9399443205965277 1.0 17.64317549184161 -6.017869217860567 22.326534387359892 0.899272370928267 0.8413499286747159 0.07161616019162087 0.09865636221332658 550.7126522964671 688087.4547573875 0.02871836123565438 0.03799023950180462 9.59689586053672e-07 6.017869217860567 -0.05792244225355103 EGRPPEPT(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EGRPPEPTPAK 11 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 EGRPPEPT(1)PAK;EGRPPEPT(1)PAK 69.258 0.025349 80382000.0 342970.0 283470.0 352410.0 340560.0 403030.0 350800.0 337250.0 356790.0 329990.0 322330.0 True False 401028.04703372554 311611.02821203513 360812.7909223673 321479.5273104167 324059.1646750631 332403.43045189447 305303.2385214421 347424.6405502525 334815.4794702545 380765.8774371232 1.0532142473821022 0.8183796045733962 0.9475974931129411 0.844297103181215 0.8510719680457075 0.8729863943934552 0.8018135463618522 0.9124363845014541 0.8793211243713491 1.0 18.53854467089255 -4.749880428383728 24.999747144561784 0.8754348061671678 1.0532146391192074 0.44993180790688747 0.05687939659896816 443.5807298647451 959318.3383234065 0.013089457967626287 0.20411339002018133 1.778769080127036e-05 4.749880428383728 0.17777983295203958 EGRPPEPT(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 2 EGRPPEPTPAK 11 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 EGRPPEPT(1)PAK;EGRPPEPT(1)PAK 72.321 0.01984 104996000.0 386380.0 296730.0 311630.0 374590.0 337460.0 238940.0 218100.0 180605.0 336060.0 246820.0 True False 380870.1503465855 296042.93991603644 286008.98432658677 402138.5981956079 317611.2662718871 228721.0931963448 229392.15082850386 188996.5676309678 298209.3839313148 289482.50813302275 1.3156931408497 1.022662618979379 0.9880009198868768 1.3891637211144292 1.097169111599443 0.7901033284237093 0.7924214568539449 0.6528773322086883 1.0301464701773342 1.0 18.14311665100314 -6.688963218999168 5.078243554654386 0.8276854760610086 1.1632373683430108 0.5097545062363897 0.15165646860434875 0.16480989986871622 7.795076241894235 0.05089150661465989 0.05022143693657366 2.0466179602930915e-07 6.688963218999168 0.3355518922820022 EGRPSGEAFVELES(ph)EDEVK ddPTM_PC-9_AZD4547_30min_R2 2 EGRPSGEAFVELESEDEVK 19 1 P31943;G8JLB6;E9PCY7;D6RBM0;D6RIU0;D6RIH9;D6RJ04;D6RDU3;E7EN40;D6RIT2;D6RFM3;D6R9T0;D6RAM1;D6RDL0;E7EQJ0 P31943;E7EQJ0 HNRNPH1 Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed 1 EGRPSGEAFVELES(1)EDEVK;EGRPSGEAFVELES(1)EDEVK 146.17 5.1107e-05 10468000.0 36145.0 35530.0 31807.0 32643.0 36667.0 42005.0 35560.0 30450.0 32851.0 37653.0 True False 47638.358137295356 47014.3776729812 31385.218397675384 25117.660679322573 31576.41996849098 39378.42070972453 38724.771111152026 25744.652171389847 34587.436793354274 36334.77993068124 1.3110952709271628 1.293922180419815 0.8637789593758782 0.6912842386066888 0.8690411784172586 1.0837665945644885 1.0657769548908886 0.7085401981381194 0.9519099017343573 1.0 15.1490635479089 -5.25768067121976 24.013157895169325 0.8971679652740441 1.302508822670508 0.6176461931208589 0.12523621548703787 121.79391951834805 778085.8105539919 0.03454311512058753 0.08420593029531762 5.524835209867759e-06 5.25768067121976 0.40534085739646386 EGRPSGEAFVELES(ph)EDEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EGRPSGEAFVELESEDEVK 19 1 P31943;G8JLB6;E9PCY7;D6RBM0;D6RIU0;D6RIH9;D6RJ04;D6RDU3;E7EN40;D6RIT2;D6RFM3;D6R9T0;D6RAM1;D6RDL0;E7EQJ0 P31943;E7EQJ0 HNRNPH1 Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed 1 EGRPSGEAFVELES(1)EDEVK;EGRPSGEAFVELES(1)EDEVK;EGRPSGEAFVELES(1)EDEVK 123.32 1.2852e-05 12272200.0 48888.0 58475.0 46784.6 53835.9 56511.0 41742.0 53844.0 47598.7 44893.0 40638.2 True False 57163.77281798641 64280.01155218799 47900.12229558354 50819.649061342716 45438.07521760783 39552.9760374087 48743.50652319805 46349.28455999141 45549.47519578812 48005.58396818582 1.1907734078575087 1.3390111365958497 0.9978031373876803 1.0586195367401807 0.9465164562464332 0.8239244847770455 1.015371598343669 0.9654977760651329 0.9488370191679075 1.0 15.550914608188673 -5.334588445364348 5.423924393318809 0.9649805461671968 1.264005053558363 0.7574179707262061 0.06689507127932556 0.09349140705061207 5.002569336749731 0.018183795710954003 0.039311490939684494 4.62819399630568e-06 5.334588445364348 0.29902450739116615 EGRPSGEAFVELES(ph)EDEVK ddPTM_PC-9_Lapatinib_30min_R1 2 EGRPSGEAFVELESEDEVK 19 1 P31943;G8JLB6;E9PCY7;D6RBM0;D6RIU0;D6RIH9;D6RJ04;D6RDU3;E7EN40;D6RIT2;D6RFM3;D6R9T0;D6RAM1;D6RDL0;E7EQJ0 P31943;E7EQJ0 HNRNPH1 Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed 1 EGRPSGEAFVELES(1)EDEVK;EGRPSGEAFVELES(1)EDEVK 114.63 3.7012e-05 11411600.0 37572.0 42012.0 34344.0 37411.0 40295.0 33752.0 37275.0 36499.0 32748.0 34778.0 True False 37036.21639013906 41914.7237952096 31520.368891673792 40162.32973943755 37924.92732301809 32308.50563975486 39204.91711202424 38194.87678615038 29059.57538827205 40789.33096122788 0.9079878369503944 1.027590372469003 0.7727601347919959 0.9846283033574067 0.929775665089174 0.7920822646114389 0.9611561697172797 0.9363938041164821 0.7124307926475798 1.0 15.315904223359597 -5.231257418221845 24.99732362889844 0.8882755910953437 0.9677890760866331 0.10376576300219509 0.09580509162072837 1617.9546058375652 1340018.7222112382 0.023174312252068823 0.061297412971608616 5.871412346963302e-06 5.231257418221845 0.07951348499128941 EGS(ph)FESR ddPTM_PC-9_AZD4547_30min_R2 1 EGSFESR 7 0 V9GY71;V9GYH5;P19174;P19174-2 V9GY71 PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1 EGS(1)FESR 70.816 0.043012 5255600.0 40270.0 61607.0 52634.0 69930.0 62913.0 38702.0 49683.0 59076.0 50759.0 50099.0 True False 53075.0223319653 81520.25795945256 51936.03876955535 53808.718907729984 54178.61590742823 36281.95782187261 54104.690751275724 49947.16163142944 53442.017113447655 48345.049258948806 1.0978377961243047 1.6862172902712045 1.0742783297493868 1.1130140465783027 1.1206652333154798 0.7504792812918009 1.1191361179813213 1.0331391196624766 1.1054289515188649 1.0 15.561080538636105 -5.424715997879241 9.288327892590827 1.0359533438191861 1.3917157150040742 0.4161938098195498 0.1675636888737993 0.3270518003384459 28.75713816557221 0.04155673637523018 0.08663397820288914 3.760832594217975e-06 5.424715997879241 0.35576237118488807 EGS(ph)GGPQESSR ddPTM_PC-9_AZD4547_30min_R2 2 EGSGGPQESSR 11 0 O96013 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 EGS(1)GGPQESSR;EGS(1)GGPQESSR 131.08 0.00017663 17978400.0 26092.0 26164.0 29822.0 42366.0 39247.0 39996.0 38706.0 30285.0 36804.0 24451.9 True False 34388.7132526853 34621.00133509374 29426.540794651344 32599.17324817512 33798.23150253267 37495.04379731323 42150.75901654247 25605.149130067042 38749.384303144834 23595.846423579125 1.4574053685279524 1.467249816497249 1.247106811360056 1.3815640542396075 1.432380551043017 1.589052713949043 1.7863635090632553 1.085154932373184 1.642212091379901 1.0 14.52624530390396 -10.862887343405136 3.402369526708063 0.9974763311177738 1.4486571157644494 0.34688062725032764 0.18685958674465927 69062584.88325854 99326546.87418877 1763106.6699656958 0.04511388850279574 1.3712374209353722e-11 10.862887343405136 0.45118078464667566 EGS(ph)GGPQESSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EGSGGPQESSR 11 0 O96013 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 EGS(1)GGPQESSR;EGS(0.986)GGPQES(0.013)S(0.001)R 113.37 0.0015719000000000002 16150500.0 19787.7 27354.0 15894.0 24202.0 28997.0 23860.0 26583.0 28026.0 21480.0 21077.0 True False 23137.36678511024 30069.52434371185 16272.973238330656 22846.040403942658 23315.246006706202 22608.73959687058 24064.865795746475 27290.347196001578 21794.104363832408 24898.093254559815 0.9292826783381447 1.207703900707535 0.6535831106404277 0.9175819276746685 0.9364269692594339 0.9080510449421677 0.9665344871876587 1.0960818130522363 0.87533226504568 1.0 14.60374764162108 -7.518700200682076 24.785378264529403 0.9976858370243407 0.9269904241251028 0.04604261601723936 0.13369766554866874 560.2635911503189 3323318.7555098208 0.06137986755706654 0.03654504861873352 3.029003668500988e-08 7.518700200682076 -0.07069541289923786 EGS(ph)GGPQESSR ddPTM_PC-9_Lapatinib_30min_R1 2 EGSGGPQESSR 11 0 O96013 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 EGS(1)GGPQESSR;EGS(1)GGPQESSR 129.76 0.00024321 19401000.0 30731.0 25920.0 29521.0 26815.0 29573.0 33635.0 29901.0 27695.0 29656.0 19961.4 True False 30292.770304624806 25859.983832520065 27093.89733435541 28787.064552217726 27833.574282755013 32196.509457014545 31449.127473283377 28981.810805568224 26315.82898847549 23411.70139310641 1.2939157985990941 1.1045751608695364 1.1572801514687534 1.229601559871855 1.1888744784243073 1.3752315099360881 1.3433080725411777 1.2379198896711512 1.1240459865178445 1.0 14.51494216244893 -8.513972680051364 2.781254007407033 1.0013406253976151 1.239534152380026 0.495597173927399 0.07744305283865491 0.237090863841711 4.389146694726522 0.08268762696302175 0.022228127106312116 3.0621560571718065e-09 8.513972680051364 0.23819352698241092 EGS(ph)IETLSNSSGSTSGSIPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGSIETLSNSSGSTSGSIPR 20 0 Q9H6U6-3;Q9H6U6-8;K7ESE9;Q9H6U6-6;Q9H6U6-2;Q9H6U6 Q9H6U6-3 BCAS3 Breast carcinoma-amplified sequence 3 1 EGS(1)IETLSNSSGSTSGSIPR 104.81 0.0019027 0.0 5283.7 5829.0 5782.4 9241.6 7544.2 5253.1 5613.5 5037.2 3809.5 4847.9 True False 6178.126052168114 6407.6645974810435 5920.27434587412 8723.823113671455 6065.96816649284 4977.618188445967 5081.7486417794435 4904.97883735457 3865.206730634062 5726.785894044714 1.078812123671805 1.118893689415624 1.0337865698856692 1.523336697944891 1.0592273360177202 0.8691818204033422 0.8873648737355373 0.8564976809164908 0.6749347368920307 1.0 12.483509951443754 -6.656481937267768 3.9598266668168662 0.8495766353579716 1.184321162427343 0.5360907437833464 0.14510928440416476 0.17923108952671302 5.223582184167508 0.05046718861012841 0.049910124780121905 2.2055558657106176e-07 6.656481937267768 0.3347445270693715 EGS(ph)LTGTK ddPTM_PC-9_Lapatinib_30min_R1 1 EGSLTGTK 8 0 E5RHL7;E5RIF2;Q9Y6D6 E5RHL7 ARFGEF1 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 1 EGS(0.999)LT(0.001)GTK 69.27600000000001 0.04131 2350600.0 15081.0 36953.0 31118.0 31898.0 31339.0 22816.0 23449.0 29986.0 22372.0 26592.0 True False 14865.942174483309 36867.437598885575 28559.59815895369 34243.885328608674 29495.70163484459 21840.212866693746 24663.074483161814 31379.259029274934 19852.22977239593 31188.39176838728 0.47664984731760063 1.182088447287449 0.9157124346469783 1.09796893610008 0.9457269183318902 0.700267363219129 0.7907773721170336 1.006119817344385 0.636526240911154 1.0 14.928721541508338 -6.5969386053537855 24.991200882554857 0.8246636346013017 0.9474234438551168 0.047221389081445686 0.20397366344395435 109.26608350756247 36867.95376604038 0.06416203627349074 0.06416204304412314 2.52965557946577e-07 6.5969386053537855 0.12275980925381513 EGS(ph)PANWK ddPTM_PC-9_AZD4547_30min_R2 3 EGSPANWK 8 0 O96019-2;O96019 O96019-2 ACTL6A Actin-like protein 6A 1 EGS(1)PANWK;EGS(1)PANWK;EGS(1)PANWK 114.89 0.0036576 393065000.0 947390.0 930860.0 997210.0 927580.0 918120.0 1035130.0 1059150.0 1080690.0 935720.0 960230.0 True False 1248640.313063836 1231742.2910405667 983986.3438345605 713740.7619681414 790654.8859047905 970403.157463566 1153412.2981545746 913694.1922856901 985180.2488897595 926612.6399712629 1.3475321393225979 1.329295800539443 1.0619176788534601 0.7702687522051035 0.8532744447877498 1.0472587094146064 1.2447621027383626 0.9860584162914361 1.063206140723823 1.0 19.821606836820386 -5.300174386966759 4.194370487552507 0.9961219863571684 1.3443836381711036 0.5633875150459974 0.11897148560816843 0.16051065034762663 6.371966473363625 0.03544127267414476 0.08462219105919071 5.009860268885239e-06 5.300174386966759 0.3482616518139352 EGS(ph)PANWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 EGSPANWK 8 0 O96019-2;O96019 O96019-2 ACTL6A Actin-like protein 6A 1 EGS(1)PANWK;EGS(1)PANWK;EGS(1)PANWK;EGS(1)PANWK;EGS(1)PANWK;EGS(1)PANWK 87.568 0.011628 419137000.0 1970600.0 2511340.0 1815200.0 2196870.0 2103870.0 1526530.0 2271340.0 1702840.0 1503270.0 1486360.0 True False 2304183.6588758845 2760649.238332135 1858481.2521843323 2073786.4962486369 1691631.7762571627 1446476.0794975192 2056182.2321224418 1658142.2543081148 1525252.4798425704 1755825.3019807101 1.3123080390039845 1.5722801324356723 1.0584659248775024 1.1810893110546028 0.9634396852288596 0.8238154888563113 1.1710631062229855 0.9443663059403454 0.8686812282075925 1.0 20.743717878602922 -5.5291815221712035 1.499610802290777 0.9716272390358518 1.4533155135691556 0.6393086277502853 0.1292339268638696 0.2701450074314255 1.1437709938839866 0.039352929105624525 0.12564091188238394 2.956776363699926e-06 5.5291815221712035 0.48168827453330376 EGS(ph)PANWK ddPTM_PC-9_Lapatinib_30min_R1 4 EGSPANWK 8 0 O96019-2;O96019 O96019-2 ACTL6A Actin-like protein 6A 1 EGS(1)PANWK;EGS(1)PANWK;EGS(1)PANWK;EGS(1)PANWK 103.31 0.004011 436099000.0 1405780.0 1785770.0 1670810.0 1559040.0 1976460.0 1632040.0 1898460.0 1776180.0 1676640.0 1464321.0 True False 1385733.3194115215 1781635.1592823793 1533442.4513131138 1673697.0024049769 1860208.5086698656 1562241.4536710577 1996752.9695638802 1858707.8070638846 1487799.1473980818 1717426.9337649164 0.8068659528785534 1.0373862923977246 0.892872017531206 0.9745375302435281 1.0831369137736448 0.909640708991524 1.1626421656184405 1.0822631056502965 0.8662954552229782 1.0 20.71181729163549 -5.999653140508024 7.655749217114929 1.0238887219775465 0.926050828059553 0.18718529046130628 0.09609044747632674 0.21034845842216976 97.29250013612297 0.026926368217553273 0.03816729776646732 1.0007989925201898e-06 5.999653140508024 -0.09783789391799358 EGS(ph)PAPLEPEPGAAQPK ddPTM_PC-9_AZD4547_30min_R2 2 EGSPAPLEPEPGAAQPK 17 0 Q01167-2;Q01167 Q01167-2 FOXK2 Forkhead box protein K2 1 EGS(1)PAPLEPEPGAAQPK;EGS(1)PAPLEPEPGAAQPK 201.4 8.428799999999999e-13 75551000.0 320400.0 351640.0 339090.0 289630.0 351750.0 390160.0 386400.0 380470.0 421000.0 337700.0 True False 422280.5352659972 465300.75330501335 334593.44504253025 222860.27823889366 302915.5841469633 365763.2335223454 420788.8514440149 321677.10383082664 443253.20051146526 325877.2257878808 1.2958270840959811 1.4278406604820117 1.0267469419919606 0.6838780393446621 0.9295389802542888 1.1223958122204807 1.2912496429496234 0.987111336341779 1.3601846506450457 1.0 18.31396900604397 -5.266933277684603 24.661770669883904 1.0434817766283253 1.3618338795475164 0.3235339948093794 0.18007693194639396 411.4285079602466 1846887.0868499319 0.050449475613748386 0.10999546988194357 5.408374074739744e-06 5.266933277684603 0.31835210291919114 EGS(ph)PAPLEPEPGAAQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EGSPAPLEPEPGAAQPK 17 0 Q01167-2;Q01167 Q01167-2 FOXK2 Forkhead box protein K2 1 EGS(1)PAPLEPEPGAAQPK;EGS(1)PAPLEPEPGAAQPK;EGS(1)PAPLEPEPGAAQPK 136.39 3.3873e-05 58609000.0 159362.0 264486.0 167538.0 191841.0 210324.0 165519.0 224081.0 139893.0 149823.0 165045.0 True False 186338.839057027 290742.42215292057 171532.74131140314 181092.77072691353 169112.52202346685 156838.89226045334 202854.42547405005 136220.95697888546 152013.87793773142 194966.35200449845 0.9557487081295322 1.4912441001420198 0.8798068976919944 0.9288411506142106 0.8673933747273731 0.8044408209311656 1.0404586401112415 0.6986895717048778 0.7796928873871735 1.0 17.572865634386382 -5.357304011102348 9.899796001631769 0.8686243780532595 1.2230275021261967 0.4526629129416686 0.15322010534693445 0.3206399798870634 31.00553454673132 0.03764841225987288 0.07847370622131922 4.39234038948104e-06 5.357304011102348 0.35440312407293717 EGS(ph)PIPHDPEFGSK ddPTM_PC-9_AZD4547_30min_R2 8 EGSPIPHDPEFGSK 14 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 EGS(1)PIPHDPEFGSK;EGS(1)PIPHDPEFGSK;EGS(1)PIPHDPEFGSK;EGS(1)PIPHDPEFGSK;EGS(1)PIPHDPEFGSK;EGS(1)PIPHDPEFGSK;EGS(1)PIPHDPEFGSK;EGS(1)PIPHDPEFGSK 146.96 2.1539e-05 642231000.0 894957.0 868522.0 907201.0 923644.0 1006605.0 1134319.0 1077359.0 1109892.0 1077402.0 1045644.0 True False 1179534.7097379863 1149254.7516265975 895170.9219853964 710712.145957548 866855.2710170699 1063389.8536134728 1173241.8638790685 938383.6941808948 1134351.2701602245 1009036.3218292638 1.168971506991571 1.1389627179556174 0.8871543101268715 0.7043474358476123 0.8590922370817767 1.053866774275947 1.1627350160716905 0.9299800947499252 1.1241927030969305 1.0 19.944546676751408 -8.25778374277725 24.519655174052414 1.0620963448025365 0.9840496277503501 0.03962443051460851 0.1445229643863878 953.897691720877 6398281.091996181 0.11943454304947623 0.04108023329682061 5.523524150610631e-09 8.25778374277725 -0.07804671705218635 EGS(ph)PIPHDPEFGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 EGSPIPHDPEFGSK 14 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 EGS(1)PIPHDPEFGSK;EGS(1)PIPHDPEFGSK;EGS(1)PIPHDPEFGSK;EGS(1)PIPHDPEFGSK;EGS(1)PIPHDPEFGSK;EGS(1)PIPHDPEFGSK;EGS(1)PIPHDPEFGSK 140.68 9.3309e-06 572919300.0 963687.0 1277683.0 1038691.0 1149475.0 1244805.0 1082624.0 1337335.0 999948.0 1022675.0 1027039.0 True False 1126820.1754141492 1404522.924327218 1063457.3326975547 1085073.642398229 1000894.3961574635 1025849.2915893726 1210652.9473330548 973700.4245324855 1037629.6871639838 1213233.04066375 0.9287747181676449 1.1576695302980002 0.8765482780750398 0.8943653906792665 0.8249811558131341 0.8455500775252038 0.9978733736683568 0.8025666890837245 0.8552599973672865 1.0 20.210425262666497 -5.2908477683701065 24.42507240193494 0.8805989611279376 1.0432221215736077 0.3711297370664869 0.08091050913491411 427.2311990531243 354835.2741459957 0.0199893639809854 0.04162437200043406 5.118612249100279e-06 5.2908477683701065 0.16262316044567016 EGS(ph)PIPHDPEFGSK ddPTM_PC-9_Lapatinib_30min_R1 5 EGSPIPHDPEFGSK 14 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 EGS(1)PIPHDPEFGSK;EGS(1)PIPHDPEFGSK;EGS(1)PIPHDPEFGSK;EGS(1)PIPHDPEFGSK;EGS(1)PIPHDPEFGSK 173.03 6.9265e-05 566450000.0 1772040.0 1637930.0 1337539.0 1278570.0 1612430.0 1544271.0 1625120.0 1565490.0 1478490.0 1444595.0 True False 1746770.3846476662 1634137.473719117 1227571.7064698497 1372600.3029844842 1517590.037559351 1478226.1292015254 1709260.7618267708 1638228.3805022244 1311966.8870100882 1694291.320948154 1.030974049769755 0.9644961604387056 0.7245340227457931 0.8101324052208176 0.8957078507078003 0.8724745921346543 1.0088352225461674 0.9669106842768009 0.7743455159033037 1.0 20.692250526138608 EGS(ph)PLHK ddPTM_PC-9_Lapatinib_30min_R1 1 EGSPLHK 7 0 Q9UDT6-2;Q9UDT6 Q9UDT6-2 CLIP2 CAP-Gly domain-containing linker protein 2 1 EGS(1)PLHK 75.378 0.018591999999999997 2743800.0 34991.0 45205.0 27370.0 36466.0 47367.0 32537.0 44610.0 45028.0 38755.0 34403.0 True False 34492.02192343647 45100.3305998869 25119.7442512553 39147.831287009925 44580.966187105034 31145.46835745152 46919.68752159361 47120.16526279569 34390.00379175777 40349.51271088399 0.8548311889311243 1.1177416422112432 0.6225538442371183 0.9702181924107867 1.104870001938825 0.7718920568042016 1.1628315776149971 1.1678001070403352 0.8523028279962677 1.0 15.300263630156937 -5.987291956177659 24.987742301161944 1.0162137474213373 0.8746578326015444 0.13678993391987293 0.1619250329260335 469.5306023499886 923226.5492814879 0.04502008711585519 0.06673145821256668 1.0296936720865142e-06 5.987291956177659 -0.1415559148197929 EGS(ph)PYKAPIYIPDDIPIPAEFELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGSPYKAPIYIPDDIPIPAEFELR 24 1 Q03112;Q03112-3;Q03112-8;C9JU02;Q03112-9 Q03112 MECOM MDS1 and EVI1 complex locus protein EVI1 1 EGS(0.568)PY(0.407)KAPIY(0.025)IPDDIPIPAEFELR 53.381 0.0059575 2067200.0 9155.0 6939.5 7889.3 11201.0 12939.0 11173.0 9330.3 9377.4 10993.0 7961.2 True False 10704.760680507796 7628.40769844222 8077.410832336868 10573.444284131969 10403.69583338868 10587.068211057625 8446.466438477724 9131.253186176586 11153.751828287232 9404.502539175473 1.1382591089657275 0.8111442010531936 0.8588876231028211 1.1242959678183022 1.106246267684118 1.1257446278477832 0.8981300609248659 0.9709448371287436 1.1860012565071965 1.0 13.199135917592315 -5.760399508359187 24.999824254384013 1.0556314517301453 0.923601700457794 0.19630604193362033 0.11277172975564624 43.402868078559614 1043400.5410050444 0.03170909020972882 0.051156541964233825 1.7362029573598467e-06 5.760399508359187 -0.13202975127235128 EGS(ph)QGELTPANSQSR ddPTM_PC-9_AZD4547_30min_R2 2 EGSQGELTPANSQSR 15 0 J3QQX0;C9JFE4;A0A096LP07;A0A096LPJ3;A8K070;Q13098-5;Q13098;Q13098-7 J3QQX0 GPS1 COP9 signalosome complex subunit 1 1 EGS(0.897)QGELT(0.036)PANS(0.065)QS(0.001)R;EGS(1)QGELTPANSQSR 127.49 2.0621999999999997e-05 30777000.0 30902.0 28561.0 19604.4 25822.0 27617.0 30201.0 31828.0 28128.0 29039.0 24463.0 True False 40728.19319847008 37792.78470920395 19344.43284671259 19869.136845923098 23782.856254119928 28312.52669573599 34660.63034099401 23781.463917138048 30573.94225570652 23606.557815957694 1.7252914853574461 1.6009443224990885 0.8194516539652397 0.8416786979629807 1.0074681975888522 1.199350066895273 1.4682627857570967 1.0074092166483553 1.295146140918477 1.0 14.526900070252402 -5.140792767978008 5.8637310093577595 1.0882646253494577 1.691813363751374 0.6059319541342477 0.188842122851377 0.15932991429615306 6.896329977515044 0.05267232220333232 0.14545501117412354 7.231147695071647e-06 5.140792767978008 0.6035487384019163 EGS(ph)QGELTPANSQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EGSQGELTPANSQSR 15 0 J3QQX0;C9JFE4;A0A096LP07;A0A096LPJ3;A8K070;Q13098-5;Q13098;Q13098-7 J3QQX0 GPS1 COP9 signalosome complex subunit 1 1 EGS(1)QGELTPANSQSR;EGS(0.985)QGELT(0.009)PANS(0.006)QSR 147.49 5.4798e-05 27661000.0 21407.0 25114.0 21570.1 19508.2 20834.5 17025.199999999997 25028.0 15434.3 16203.7 14978.8 True False 25030.782292477383 27607.15194735614 22084.41298905978 18415.218800437753 16752.129286709674 16132.36854084831 22657.166652971548 15029.165978992614 16440.64845811132 17694.33786788445 1.4146210205417584 1.560225206135779 1.248106210809018 1.040740769049161 0.9467508426588315 0.911724906651006 1.2804755296379144 0.84937713358977 0.929147424496251 1.0 14.111000155859506 -5.574979745113433 2.4709541649552906 0.9905384948410387 1.4879850421227976 0.7522380641075119 0.11420946927461641 0.13708641677769465 1.675463035385275 0.03309713231611005 0.07238308100093697 2.6608491551840307e-06 5.574979745113433 0.49744654728175886 EGS(ph)QGELTPANSQSR ddPTM_PC-9_Lapatinib_30min_R1 3 EGSQGELTPANSQSR 15 0 J3QQX0;C9JFE4;A0A096LP07;A0A096LPJ3;A8K070;Q13098-5;Q13098;Q13098-7 J3QQX0 GPS1 COP9 signalosome complex subunit 1 1 EGS(0.968)QGELT(0.013)PANS(0.009)QS(0.009)R;EGS(1)QGELTPANSQSR;EGS(0.926)QGELT(0.07)PANS(0.001)QS(0.003)R 120.99 7.2791e-05 34569300.0 28501.3 29911.8 28915.699999999997 33697.0 40751.1 32741.1 37455.6 32681.2 29903.8 31619.1 True False 28094.866235501722 29842.541064875502 26538.36276382985 36175.18978989675 38354.20041774519 31340.83947623187 39394.86769634165 34199.68786058627 26535.719143025806 37084.41930519758 0.757592184585295 0.8047191144959606 0.7156202863910115 0.9754821692684993 1.0342402857139963 0.8451214839931249 1.0623024017749754 0.9222117671340482 0.7155489998277169 1.0 15.17852555797311 -5.7637160436961645 24.99987191603243 0.9386915629811475 0.7638513725518565 0.4158822577427642 0.09611276571454226 58.75635177016527 645211.1523381145 0.02687931837461982 0.042135963348533596 1.7229947585611213e-06 5.7637160436961645 -0.174840190429291 EGS(ph)SPEGSTRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGSSPEGSTRR 11 1 Q9Y2I9;F8VZ81;Q9Y2I9-2 Q9Y2I9 TBC1D30 TBC1 domain family member 30 1 EGS(0.5)S(0.5)PEGSTRR 71.241 0.013853 6293800.0 10538.0 8588.1 13257.0 14372.0 15738.0 18498.0 10549.0 11958.0 18387.0 12397.0 True False 12321.8752650127 9440.669811224387 13573.097157452481 13566.783434652678 12654.251876178298 17527.932316132083 9549.7223518538 11644.115170548299 18655.87509021354 14644.477965401991 0.8414007856151303 0.6446573127105142 0.9268406282230969 0.9264094948761302 0.8640971638643821 1.1968970391121034 0.6521039790162065 0.7951198532346365 1.2739187517840234 1.0 13.838069145648316 -2.5901891994645885 0.2453195381527027 1.0094581764754038 6.671321714167485e-10 0.15834315512924768 0.1789039448149634 61.78461004932801 1.31638135366092 0.24657175447020202 22.965448963087763 0.0025692762392104497 2.5901891994645885 -1.0094581758082717 EGSALSHVR ddPTM_PC-9_AZD4547_30min_R2 2 EGSALSHVR 9 0 K7ELG9;Q3MHD2;Q3MHD2-2 K7ELG9 LSM12 Protein LSM12 homolog 0 ; 119.75 0.00014457 1362000.0 20746.8 21436.0 45742.0 64921.0 53076.0 45090.0 35259.0 52239.0 40147.0 46309.0 False True 27343.850839752104 28364.767796172968 45135.43119270814 49954.46646945136 45707.31355844839 42270.51517203856 38396.982694266255 44166.66288279914 42269.08845827507 44687.73600536259 0.6118871369198655 0.6347327103966323 1.0100183009336572 1.1178562830629137 1.0228156009730154 0.9459086306579962 0.8592286413806813 0.9883396840130607 0.9458767043647663 1.0 15.447591335524866 -5.257782046270243 23.376358080124298 0.9858671675703213 0.6233097945613026 0.843618591334841 0.06250571369559318 49.055506298554775 313535.3242674678 0.018258945941604477 0.04441036816055371 5.523545727480963e-06 5.257782046270243 -0.3625573730090187 EGSALSHVR ddPTM_PC-9_Lapatinib_30min_R1 2 EGSALSHVR 9 0 K7ELG9;Q3MHD2;Q3MHD2-2 K7ELG9 LSM12 Protein LSM12 homolog 0 ; 117.53 0.0015550000000000002 4471300.0 31244.1 35645.0 42900.0 36349.0 39493.0 44229.0 39791.0 34336.0 42873.0 37863.0 False True 30798.553404533803 35562.46619252229 39372.92759878891 39022.226716709374 37170.09938622543 42337.42877283472 41851.18328114171 35931.375909730676 38044.191267295326 44407.5691007238 0.6935428808246074 0.8008199258072575 0.8866265007545115 0.8787291785371191 0.8370217091126386 0.9533831648565664 0.9424335564555724 0.8091272870224511 0.8567051076586681 1.0 15.438517978949095 -4.69320817243047 1.3234260876898054 0.8927931303492109 0.5728728471700669 0.582118217983086 0.05415114376275099 1.2112052741773798 1.625313956575912 0.01611178613417594 0.5546810813453836 2.026711013666695e-05 4.69320817243047 -0.319920283179144 EGSCIFPEELS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 EGSCIFPEELSPK 13 0 Q86YC2;H3BN63 Q86YC2 PALB2 Partner and localizer of BRCA2 1 EGSCIFPEELS(1)PK;EGSCIFPEELS(1)PK;EGSCIFPEELS(1)PK;EGSCIFPEELS(1)PK 131.66 6.5564e-05 10776100.0 110214.0 106456.0 109794.0 124724.0 121500.0 112862.0 118073.0 110536.0 102606.0 122998.0 True False 145259.7594063877 140865.8201394564 108338.05982187488 95970.808766591 104631.82224266086 105804.72129843918 128581.26826229047 93455.20106458952 108029.54368569948 118691.87745767758 1.223839090911537 1.1868193776754898 0.9127672604261012 0.8085709892053201 0.8815415551916754 0.8914234365882904 1.0833198616151236 0.7873765506650883 0.9101679575691267 1.0 16.856861683616422 -5.2498203485816655 4.867315035286763 0.9018039015338998 1.2122270681424487 0.6827108725190714 0.08073486513813552 0.09721006173529712 6.86317918588235 0.021066553897272303 0.053863569580803544 5.625739929284226e-06 5.2498203485816655 0.31042316660854896 EGSCIFPEELS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EGSCIFPEELSPK 13 0 Q86YC2;H3BN63 Q86YC2 PALB2 Partner and localizer of BRCA2 1 EGSCIFPEELS(1)PK;EGSCIFPEELS(1)PK;EGSCIFPEELS(1)PK;EGSCIFPEELS(1)PK 160.27 4.9634e-05 12934200.0 80361.0 86948.0 64895.0 95095.0 88898.0 67283.0 83068.0 75635.0 68494.0 71276.8 True False 93964.53009790153 95579.62282068674 66442.34291565802 89767.13545214951 71479.07505963267 63754.56103504781 75199.19767976046 73649.66139190683 69495.59517208283 84198.71961316174 1.1159852611727035 1.1351671766484435 0.7891134594554087 1.06613421040808 0.8489330406451838 0.7571915740281857 0.893115691369795 0.8747123677210181 0.8253759141631822 1.0 16.36151067434009 -5.249631962452811 24.731119426195487 0.8787077026266842 1.1255762711250825 0.5530273808269874 0.08761972493740733 461.40561899219773 966427.9946596965 0.022067378091651883 0.05735041247336171 5.628180764488261e-06 5.249631962452811 0.24686856849839833 EGSCIFPEELS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 EGSCIFPEELSPK 13 0 Q86YC2;H3BN63 Q86YC2 PALB2 Partner and localizer of BRCA2 1 EGSCIFPEELS(1)PK;EGSCIFPEELS(1)PK;EGSCIFPEELS(1)PK;EGSCIFPEELS(1)PK 150.11 0.00012572 14047200.0 96796.0 116299.0 98729.0 111321.0 118134.0 105589.0 101787.0 103857.0 101628.0 97074.0 True False 95415.67128978774 116029.71681088916 90611.88272496112 119507.91769596968 111185.59038038019 101073.2046099809 107057.03281238388 108682.57536861904 90181.5844497164 113853.11155702578 0.838059408169945 1.019117661556164 0.7958665466914026 1.049667559029439 0.9765705026400662 0.8877509207058975 0.9403083617856335 0.9545859035585781 0.7920871306582343 1.0 16.796814194690867 EGSEFSFS(ph)DGEVAEK ddPTM_PC-9_AZD4547_30min_R2 2 EGSEFSFSDGEVAEK 15 0 Q9BVS4;Q9BVS4-2 Q9BVS4 RIOK2 Serine/threonine-protein kinase RIO2 1 EGSEFS(0.123)FS(0.877)DGEVAEK;EGSEFS(0.013)FS(0.987)DGEVAEK 168.68 0.00019666 13291100.0 31809.0 30533.0 34204.0 30993.0 32603.0 35680.0 37992.0 44853.0 36224.0 36758.0 True False 41923.600331698115 40402.195144642144 33750.4326115034 23848.04268707669 28076.63621874468 33448.92395959935 41373.214399743716 37921.999469403876 38138.726687238304 35471.11360826444 1.1819082083154646 1.139016823402714 0.9514906406445571 0.6723229202908453 0.7915352342420703 0.9429905226264468 1.1663917534887922 1.0690952612372566 1.0752052249736062 1.0 15.114357003645527 -7.196182274191818 9.69656535158943 1.0833428735600574 0.9358266435636418 0.16381879353456164 0.14370090638742497 1.031639035145643 148.95393327853694 0.06295007613440123 0.04872849752575782 6.365283127358525e-08 7.196182274191818 -0.14751622999641567 EGSEFSFS(ph)DGEVAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EGSEFSFSDGEVAEK 15 0 Q9BVS4;Q9BVS4-2 Q9BVS4 RIOK2 Serine/threonine-protein kinase RIO2 1 EGS(0.011)EFS(0.348)FS(0.642)DGEVAEK;EGSEFS(0.234)FS(0.766)DGEVAEK;EGSEFS(0.001)FS(0.999)DGEVAEK 171.15 0.0001325 13751490.0 40126.8 50966.5 46548.0 37231.6 46912.3 37769.8 46021.7 37387.4 37286.6 32727.0 True False 46919.474699574064 56026.11729413583 47657.88085427306 35145.6341584758 37720.17157776332 35789.08519806716 41662.1914077458 36406.02036522476 37831.845985683154 38660.14603321054 1.2136393550937041 1.4491956974504767 1.2327392869476779 0.9090921210769446 0.975686215601986 0.9257359029974426 1.077652199553421 0.941693813933103 0.978574833969436 1.0 15.238559466684494 -5.633209292761322 4.544677504801762 0.9734592353706595 1.3336470566001553 0.8257872453587237 0.06937715404999137 0.07266628328441352 2.5469690374671075 0.018042004674227362 0.032261759180819305 2.326969587277632e-06 5.633209292761322 0.3601878212294958 EGSEFSFS(ph)DGEVAEK ddPTM_PC-9_Lapatinib_30min_R1 2 EGSEFSFSDGEVAEK 15 0 Q9BVS4;Q9BVS4-2 Q9BVS4 RIOK2 Serine/threonine-protein kinase RIO2 1 EGSEFS(0.082)FS(0.918)DGEVAEK;EGS(0.053)EFS(0.034)FS(0.913)DGEVAEK 159.88 0.00017514 12876700.0 32642.0 43003.0 42932.0 33710.0 42016.0 41222.0 38871.0 40321.0 44222.0 40006.0 True False 32176.519094190346 42903.429195596465 39402.29668231248 36189.145853263435 39544.70148663424 39459.03115317537 40883.550182736304 42194.46085904736 39241.25268169554 46920.983795355794 0.6857596855711102 0.9143761644623277 0.8397585364826151 0.7712784968682905 0.8427935283519854 0.8409676857005925 0.8713276422559352 0.8992663291775168 0.8363262981195124 1.0 15.51794564231488 -14.522878740999499 0.10445537800216124 1.5268274026551654 0.734643730491428 0.5008944752332711 0.056129489212428975 154.32761791066127 1.081793971963503 17.477038741878243 0.8079842074329573 3.000000029570988e-15 14.522878740999499 -0.7921836721637374 EGSFES(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 EGSFESR 7 0 V9GY71;V9GYH5;P19174;P19174-2 V9GY71 PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1 EGS(0.494)FES(0.506)R 80.555 0.042811 0.0 96215.0 107420.0 48306.0 40217.0 48319.0 42985.0 41198.0 39717.0 54364.0 43447.0 True False 94842.95645633005 107171.27558986508 44334.46714655238 43174.692339979156 45476.97141880905 41146.63175292911 43331.030856637815 41562.39681403698 48240.95384170089 50956.756060511514 1.8612439995925831 2.1031808905299707 0.8700410028830109 0.8472810217492829 0.8924620587072855 0.807481380958929 0.8503490843330354 0.8156405553893843 0.9467037851548951 1.0 15.636985817183376 -5.265291721896008 24.999795692685723 0.8679674966773473 1.9822125008043836 0.9698007611151285 0.07787045429490855 39.038199297670076 253340.25615793015 0.018594892521301365 0.04119829191842865 5.4288554490352386e-06 5.265291721896008 1.1142450041270364 EGSIETLSNSSGSTSGS(ph)IPR ddPTM_PC-9_AZD4547_30min_R2 1 EGSIETLSNSSGSTSGSIPR 20 0 Q9H6U6-3;Q9H6U6-8;K7ESE9;Q9H6U6-6;Q9H6U6-2;Q9H6U6 Q9H6U6-3 BCAS3 Breast carcinoma-amplified sequence 3 1 EGSIETLS(0.015)NS(0.048)S(0.002)GS(0.025)T(0.001)S(0.329)GS(0.579)IPR 168.83 4.3842999999999995e-28 0.0 10539.0 9254.9 12740.0 17608.0 15494.0 16600.0 11823.0 14477.0 9766.2 13735.0 True False 13890.182775182077 12246.36543556638 12571.059275831885 13548.74764088816 13342.925545907738 15561.999375822568 12875.224095814121 12239.912298364889 10282.421393907542 13254.141830608622 1.0479880895121105 0.923965171949879 0.9484627097320438 1.0222274526743924 1.0066985638477235 1.1741234985040123 0.9714113716574662 0.9234782949204973 0.7757892985694254 1.0 13.694155642224983 -7.765766797136784 3.4087577135819975 0.8805177526210339 1.0156832902357111 0.30079559456256466 0.08120200594475184 0.2826910437955314 6.838795496360046 0.04802860512416255 0.022794032785876252 1.7148778973401775e-08 7.765766797136784 0.1351655376146772 EGSITQGT(ph)PLKYDTGASTTGSK ddPTM_PC-9_AZD4547_30min_R2 2 EGSITQGTPLKYDTGASTTGSK 22 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 EGS(0.033)IT(0.187)QGT(0.772)PLKY(0.004)DT(0.001)GAS(0.001)T(0.001)TGSK;EGS(0.018)IT(0.103)QGT(0.878)PLKY(0.001)DTGAS(0.001)TTGSK 77.681 0.00051041 24579300.0 20712.8 20961.9 28528.8 31804.6 33119.7 31147.7 32704.0 36070.0 30697.6 32876.6 True False 27299.039546996042 27737.42424270378 28150.48947161321 24472.54084617171 28521.601342635884 29200.029395078833 35614.59264395713 30496.210306142235 32320.212465607525 31725.60024085823 0.8604735399722592 0.8742915510541475 0.8873114852956898 0.7713814919301172 0.8990090376888745 0.9203932840795614 1.122582153641664 0.9612492773853744 1.0187423475122628 1.0 14.95335983932324 -6.95684251733733 3.1009570529180537 1.0229024909442364 0.8557638806307298 0.7042703027907709 0.050661418633496866 0.13909172908710155 2.7409090750508156 0.01933085899109279 0.016134093663857887 1.1044790504316627e-07 6.95684251733733 -0.16713861031350652 EGSITQGT(ph)PLKYDTGASTTGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGSITQGTPLKYDTGASTTGSK 22 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 EGS(0.006)IT(0.159)QGT(0.833)PLKY(0.001)DTGASTTGSK 92.932 0.00013764 11608000.0 10606.0 10878.0 7784.4 13944.0 12645.0 11152.0 13805.0 12307.0 9487.6 6756.0 True False 12401.386321951471 11957.895949802505 7970.009618501402 13162.762887057952 10167.303022892014 10567.169488026007 12497.29046045519 11983.954290344363 9626.338201224224 7980.809319533426 1.5539008420610256 1.4983312432405775 0.9986467912463977 1.6493017637749392 1.2739689191680144 1.3240724173377174 1.5659176858000419 1.5015963683047835 1.2061857157347795 1.0 12.962319339640183 -8.518266837610339 4.0367151597591056 1.0008654152104255 1.4124397882130124 0.36641578012356624 0.17715312818240944 0.19537997610731192 9.284724381869278 0.16758046353805003 0.04391342759692711 3.032027684527608e-09 8.518266837610339 0.4115743730025869 EGSITQGT(ph)PLKYDTGASTTGSK ddPTM_PC-9_Lapatinib_30min_R1 1 EGSITQGTPLKYDTGASTTGSK 22 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 EGS(0.013)IT(0.041)QGT(0.946)PLKYDTGASTTGSK 93.949 0.00013338 14097000.0 34821.0 38780.0 39433.0 36513.0 31888.0 38786.0 29287.0 25600.0 36380.0 24536.0 True False 34324.44615461066 38690.207292636085 36190.970955781915 39198.287823797364 30012.410534220126 37127.21319458199 30803.337557608447 26789.469457394738 32282.5013016165 28777.014907835062 1.192772991380187 1.3444829985511102 1.2576346459732441 1.362138774620606 1.0429299435796833 1.2901690225164195 1.070414622790555 0.9309328831775675 1.121815497716096 1.0 14.812629326005013 -7.078271830454737 0.9583777319977895 1.0070959915711861 1.2816158002059903 0.5349966460734115 0.09732187001658688 0.4172902827191671 0.7789637687863402 0.06503249962824793 0.04369282574890734 8.35080167292381e-08 7.078271830454737 0.2745198086348042 EGSQGELT(ph)PANSQSR ddPTM_PC-9_AZD4547_30min_R2 1 EGSQGELTPANSQSR 15 0 J3QQX0;C9JFE4;A0A096LP07;A0A096LPJ3;A8K070;Q13098-5;Q13098;Q13098-7 J3QQX0 GPS1 COP9 signalosome complex subunit 1 1 EGSQGELT(1)PANSQSR 166.77 0.00060172 27627000.0 22844.0 18463.0 23077.0 34614.0 24403.0 27128.0 31424.0 34796.0 23375.0 23494.0 True False 30107.91681528221 24430.80368635667 22770.983901756055 26634.277080969023 21015.064676441623 25431.681871524972 34220.67512364568 29419.077732534657 24610.55477899171 22671.482211017046 1.32800831172174 1.0776006376188627 1.004388848060876 1.174792050782912 0.9269382778259421 1.1217476490869498 1.5094149912711212 1.2976248071790677 1.0855291484661902 1.0 14.468591093900363 -7.026429157113535 24.976251911132486 1.2576067418868546 1.0920325622877163 0.09830947554372493 0.1608291897458615 1242.7887879315044 1174464.7353437038 0.060516061117556676 0.04703855831452973 9.409593084703715e-08 7.026429157113535 -0.16557417959913834 EGSQGELT(ph)PANSQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGSQGELTPANSQSR 15 0 J3QQX0;C9JFE4;A0A096LP07;A0A096LPJ3;A8K070;Q13098-5;Q13098;Q13098-7 J3QQX0 GPS1 COP9 signalosome complex subunit 1 1 EGSQGELT(0.818)PANS(0.091)QS(0.091)R 93.738 0.0077816000000000005 23753000.0 28049.0 26935.0 42882.0 30184.0 40867.0 36158.0 39955.0 33640.0 33660.0 28099.0 True False 32797.141706997645 29608.928792786388 43904.46951089061 28492.88833784833 32859.404716214165 34261.81082747889 36170.17315085019 32756.98564452627 34152.21382153627 33193.12626843839 0.9880702842438416 0.8920198884954073 1.322697631908118 0.8583972509073581 0.9899460644494477 1.0321959598019743 1.0896886559685859 0.986860513818886 1.0288941615604863 1.0 15.018596894460348 -6.878914613331165 19.303040462355828 1.0306001533016327 1.012424296836974 0.0047453000334430895 0.11913697576940596 20.951352708830438 3395.186656407555 0.041842546786413574 0.036901714567235636 1.3215554397541177e-07 6.878914613331165 -0.01817585646465858 EGSQGELT(ph)PANSQSR ddPTM_PC-9_Lapatinib_30min_R1 1 EGSQGELTPANSQSR 15 0 J3QQX0;C9JFE4;A0A096LP07;A0A096LPJ3;A8K070;Q13098-5;Q13098;Q13098-7 J3QQX0 GPS1 COP9 signalosome complex subunit 1 1 EGSQGELT(0.998)PANS(0.001)QS(0.001)R 83.25200000000001 0.017023 21333000.0 14238.0 18631.0 21786.0 18712.0 20355.0 20953.0 18113.0 18565.0 22511.0 13512.0 True False 14034.963509070576 18587.861064185232 19994.839176391964 20088.142901402138 19157.758919469732 20056.88903382862 19050.80251241034 19427.597674864584 19975.574128661046 15847.531196391727 0.885624602036824 1.1729184081629977 1.261700572070464 1.2675881594715486 1.2088797101615234 1.2656159994432008 1.2021306206198197 1.2259068894773963 1.2604849222956078 1.0 13.951970487539379 -4.766962343292971 3.6397858542371484 1.2230304044966103 0.8423150176074274 0.6201646714618687 0.07559544541553263 0.16374241910034149 3.65539598353357 0.01726185471778541 0.17434992995435672 1.7101635931371186e-05 4.766962343292971 -0.3807153868891828 EGSQGEPWT(ph)PTANLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGSQGEPWTPTANLK 15 0 A0AVK6;E9PMT9 A0AVK6 E2F8 Transcription factor E2F8 1 EGS(0.004)QGEPWT(0.866)PT(0.13)ANLK 128.82 4.1283000000000004e-05 5841200.0 23413.0 26583.0 25060.0 28366.0 37012.0 33102.0 33846.0 39680.0 31680.0 21835.0 True False 27376.358472171392 29221.98455907334 25657.525440579255 26776.74498381281 29759.764292865093 31366.072847259402 30639.8618561801 38638.44204443527 32143.26006732826 25793.5126542351 1.0613660434371432 1.1329199303250117 0.9947278520968134 1.0381193652356717 1.153769348587687 1.216045029140664 1.1878902368557107 1.4979906987616567 1.2461761411953554 1.0 14.654720637506415 -6.703973286907613 1.7083946787901039 1.2708402452850773 1.0582007694165325 0.2952299647034625 0.11971408943220682 0.3845666749620857 2.3207790261173944 0.04880267319812323 0.04650400902004868 1.9770912456101034e-07 6.703973286907613 -0.2126394758685448 EGSQGEPWTPT(ph)ANLK ddPTM_PC-9_AZD4547_30min_R2 2 EGSQGEPWTPTANLK 15 0 A0AVK6;E9PMT9 A0AVK6 E2F8 Transcription factor E2F8 1 EGSQGEPWT(0.12)PT(0.88)ANLK;EGSQGEPWT(0.185)PT(0.815)ANLK 121.45 0.00016056 19168200.0 42530.0 39386.0 69511.0 76032.0 81467.0 64188.0 59900.0 64763.0 57428.0 64342.0 True False 56053.65532104503 52116.7542647914 68589.23872231953 58503.99708269017 70156.7132727807 60174.314212969875 65230.98395832414 54755.366455688665 60463.52683841434 62089.40616418063 0.9027893610839908 0.8393823920135598 1.1046850495067007 0.9422540928800365 1.1299304922850768 0.9691558984128991 1.0505976460112432 0.881879371029917 0.9738139011755558 1.0 15.922059513080647 -5.241719403913369 24.867596652279232 1.0046702490199728 0.8710858568315901 0.3650094561441023 0.07142913851578471 816.2811234304619 1029355.8709523755 0.017764873282904544 0.04685075915109071 5.731662319999262e-06 5.241719403913369 -0.1335843921883827 EGSS(ph)PEGSTRR ddPTM_PC-9_Lapatinib_30min_R1 1 EGSSPEGSTRR 11 1 Q9Y2I9;F8VZ81;Q9Y2I9-2 Q9Y2I9 TBC1D30 TBC1 domain family member 30 1 EGS(0.018)S(0.508)PEGS(0.237)T(0.237)RR 92.11200000000001 0.011495 1918900.0 15861.0 15318.0 15761.0 16042.0 14282.0 14848.0 16193.0 15420.0 18552.0 11864.0 True False 15634.819231448835 15282.532112135119 14465.191419219402 17221.782194543233 13441.960839492353 14212.985652378537 17031.39430704248 16136.469493477605 16462.478398779258 13914.676592213695 1.1236207415842987 1.0983030766727875 1.039563609212 1.237670317410044 0.966027542962381 1.0214384472530083 1.2239877940514134 1.1596726223954907 1.1831017623500677 1.0 13.764319757192624 -7.257359154211118 24.997335336234205 1.1549965954106254 1.0818834454598636 0.09775156854096612 0.08645450447562325 740.006288170834 4533631.926959229 0.03337073026188114 0.024871225502141447 5.5289268717521496e-08 7.257359154211118 -0.07311314995076179 EGSTQQLQT(ph)TSPK ddPTM_PC-9_Lapatinib_30min_R1 1 EGSTQQLQTTSPK 13 0 A0A087X0H9;Q5T8P6-3;Q5T8P6-2;Q5T8P6;Q5T8P6-5;Q5T8P6-4 A0A087X0H9 RBM26 RNA-binding protein 26 1 EGST(0.001)QQLQT(0.522)T(0.238)S(0.238)PK 109.95 0.0017844000000000002 5525100.0 43251.0 35254.0 31747.0 30144.0 30740.0 33350.0 30583.0 29191.0 25795.0 31582.0 True False 42634.232808737994 35172.37152899932 29136.8842069639 32360.8903174362 28931.93363716529 31923.6982426471 32166.438096231734 30547.320426984727 22889.695466607947 37040.906619630216 1.151004030396587 0.9495548230009941 0.7866136891887657 0.8736527604398918 0.781080601894137 0.8618498075781116 0.8684030989453372 0.824691488809182 0.6179572142134694 1.0 15.176831790232837 -4.854640800003414 2.376104623921657 0.8232077528962821 1.2005049287292862 0.5435512169014989 0.09131762161368892 0.3415772340563584 2.706155123396698 0.023011578011436593 0.25366174219613896 1.397523759091865e-05 4.854640800003414 0.37729717583300404 EGSTQQLQT(ph)TSPKPLVQQPILPVVK ddPTM_PC-9_AZD4547_30min_R2 1 EGSTQQLQTTSPKPLVQQPILPVVK 25 1 A0A087X0H9;Q5T8P6-3;Q5T8P6-5;Q5T8P6-4 A0A087X0H9 RBM26 RNA-binding protein 26 1 EGS(0.101)T(0.093)QQLQT(0.269)T(0.269)S(0.269)PKPLVQQPILPVVK 43.888000000000005 0.040525 12538000.0 21565.0 16168.0 22817.0 27798.0 30076.0 23897.0 21626.0 25259.0 24181.0 21825.0 True False 28422.22142013487 21393.98981752773 22514.43167163705 21389.60057481877 25900.466549549583 22402.716812291077 23550.672104886784 21355.801944076724 25459.158293510074 21060.91339301298 1.3495246331321995 1.0158149087980795 1.0690149687005635 1.0156065017538525 1.2297883793654525 1.0637105995470855 1.1182170338680464 1.0140016981011648 1.2088344801776842 1.0 14.36228038566593 -2.7276300631742942 0.011833361176479514 5.702411995449474e-07 2.339251410377663 0.11011610874343147 0.10523688581246857 20215.28690422083 22.827873396618667 1955.4514225355606 2597.6325615977644 0.0018722762868876894 2.7276300631742942 2.3392508401364633 EGSTQQLQT(ph)TSPKPLVQQPILPVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGSTQQLQTTSPKPLVQQPILPVVK 25 1 A0A087X0H9;Q5T8P6-3;Q5T8P6-5;Q5T8P6-4 A0A087X0H9 RBM26 RNA-binding protein 26 1 EGS(0.028)T(0.026)QQLQT(0.369)T(0.312)S(0.265)PKPLVQQPILPVVK 55.04600000000001 0.0046542 7171900.0 15279.0 16004.0 12371.0 18218.0 14407.0 17286.0 17867.0 15041.0 16438.0 17710.0 True False 17865.4329259944 17592.77135324869 12665.971557278763 17197.304523552917 11584.051771514853 16379.491729736148 16174.508414121907 14646.189687256818 16678.37465235929 20920.682807717127 0.8539603171749385 0.8409272065804251 0.6054282106225805 0.8220240554103355 0.5537128915907936 0.7829329415431009 0.7731348236949287 0.7000818195978861 0.797219421834886 1.0 14.352642318478074 -8.6387357232121 4.6875368964431345 0.9999899913689837 0.739447821665881 0.4073151455848195 0.09342642820521814 0.8994801767154159 35.28341709422523 0.08828284759237083 0.022997834560527015 2.297546325224631e-09 8.6387357232121 -0.26054216970310273 EGSTQQLQT(ph)TSPKPLVQQPILPVVK ddPTM_PC-9_Lapatinib_30min_R1 1 EGSTQQLQTTSPKPLVQQPILPVVK 25 1 A0A087X0H9;Q5T8P6-3;Q5T8P6-5;Q5T8P6-4 A0A087X0H9 RBM26 RNA-binding protein 26 1 EGS(0.002)T(0.007)QQLQT(0.33)T(0.33)S(0.33)PKPLVQQPILPVVK 67.76 0.00048653 7546700.0 46930.0 36725.0 42898.0 38953.0 41127.0 44832.0 38705.0 38423.0 38171.0 38189.0 True False 46260.76959409201 36639.96551887726 39371.09203106869 41817.73356339876 38707.990718793015 42914.639868496364 40708.9555149805 40208.27285005772 33871.7800215504 44789.917766356084 1.0328389044027393 0.8180404730816305 0.8790168411660327 0.9336416686795108 0.864212140792732 0.958131695895447 0.9088865875426769 0.8977081194880009 0.7562367093023146 1.0 15.450886396978175 -7.847408476417637 0.002595853533030854 1.0880635156721448 0.7134415072683752 0.0 0.07825478219486146 829549.3698512753 2167.0231562890817 156273.5415046586 156444.63194995534 1.4209916422752922e-08 7.847408476417637 -0.3746220084037696 EGSTQQLQTT(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 3 EGSTQQLQTTSPK 13 0 A0A087X0H9;Q5T8P6-3;Q5T8P6-2;Q5T8P6;Q5T8P6-5;Q5T8P6-4 A0A087X0H9 RBM26 RNA-binding protein 26 1 EGSTQQLQT(0.003)T(0.643)S(0.355)PK;EGSTQQLQT(0.007)T(0.497)S(0.497)PK;EGSTQQLQT(0.011)T(0.895)S(0.095)PK 184.0 0.00013282 23779000.0 197657.0 185262.0 155073.0 207253.0 195489.0 197556.0 197383.0 187523.0 176283.0 197287.0 True False 260507.8144789984 245144.31850413294 153016.63069710185 159474.02287693048 168348.7267357659 185202.7920897591 214949.70461846178 158545.6291998532 185600.95949112278 190380.04217948928 1.3683567431579464 1.287657654120132 0.8037430234038849 0.8376614536442808 0.8842771795220407 0.9728057099344002 1.1290558724417572 0.8327849252726671 0.9748971445028843 1.0 17.53852272116127 -5.175308099332284 5.631753135274811 0.927714199497502 1.3429291502964582 0.7470560024100397 0.09298859094833174 0.11061457856875245 5.590391606392242 0.02508080123067663 0.06922500976005758 6.678699458754385e-06 5.175308099332284 0.4152149507989562 EGSTQQLQTT(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EGSTQQLQTTSPK 13 0 A0A087X0H9;Q5T8P6-3;Q5T8P6-2;Q5T8P6;Q5T8P6-5;Q5T8P6-4 A0A087X0H9 RBM26 RNA-binding protein 26 1 EGSTQQLQT(0.002)T(0.499)S(0.499)PK;EGSTQQLQTT(0.699)S(0.301)PK;EGSTQQLQTT(0.72)S(0.28)PK 170.74 0.00023996 24646700.0 188964.0 175981.0 134060.0 178640.0 171202.0 155756.0 188905.0 158335.0 139027.0 134304.0 True False 220951.87299087684 193451.23066208776 137256.49882538104 168631.3799586945 137656.19708383983 147587.88116723282 171010.5508462357 154178.87401980005 141060.00686175644 158652.25205012123 1.3926803441849285 1.2193412205770195 0.865140564043296 1.062899377598628 0.8676598995919178 0.9302602343180545 1.0778955144753335 0.9718038794122635 0.8891144313362342 1.0 17.27550847472471 -5.052723077848035 3.5691451136030716 0.9614767596131567 1.3731634510415165 0.7984358344546585 0.07215905383555223 0.09257330541499377 2.3107801755121655 0.018486772636021685 0.06930836579124737 8.856801721064842e-06 5.052723077848035 0.4116866914283598 EGSTQQLQTT(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 3 EGSTQQLQTTSPK 13 0 A0A087X0H9;Q5T8P6-3;Q5T8P6-2;Q5T8P6;Q5T8P6-5;Q5T8P6-4 A0A087X0H9 RBM26 RNA-binding protein 26 1 EGSTQQLQT(0.006)T(0.785)S(0.21)PK;EGSTQQLQTT(0.5)S(0.5)PK;EGSTQQLQTT(0.74)S(0.259)PK 179.46 0.00026931 28795000.0 163042.0 142211.0 119402.0 132740.0 138257.0 121063.0 133079.0 126947.0 113253.0 114605.0 True False 160716.99118175884 141881.71916691767 109585.22846504858 142502.14240765927 130124.99508372032 115885.41770163675 139969.1794594519 132845.421062808 100497.25453303936 134414.32154843674 1.195683535283432 1.055555074284179 0.8152794077494123 1.0601708267843173 0.9680887689994347 0.8621508211822277 1.0413263843244074 0.9883278770628368 0.7476677587278137 1.0 17.036327336706336 -4.9560379276318995 4.06210766264188 0.9409719732042447 1.183946339644634 0.42265061147232497 0.09538722701465698 0.20396557232653995 7.060207944411892 0.02347721780725772 0.10886325640589473 1.1065271449720888e-05 4.9560379276318995 0.24297436644038917 EGSTQQLQTT(ph)SPKPLVQQPILPVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGSTQQLQTTSPKPLVQQPILPVVK 25 1 A0A087X0H9;Q5T8P6-3;Q5T8P6-5;Q5T8P6-4 A0A087X0H9 RBM26 RNA-binding protein 26 1 EGSTQQLQT(0.093)T(0.453)S(0.453)PKPLVQQPILPVVK 83.905 8.6142e-06 5719200.0 34944.0 30840.0 31094.0 36621.0 39876.0 33081.0 35261.0 36017.0 30579.0 26937.0 True False 40859.3290245401 33901.591385540465 31835.398884651673 34569.24409688391 32062.58405226114 31346.174124227782 31920.822812467257 35071.591913165954 31026.160025215624 31820.464866825332 1.2840582057975622 1.0654021406483232 1.0004693211707887 1.0863840060653651 1.007608914151604 0.9850947890113313 1.0031538805627744 1.1021709475316341 0.9750379246521375 1.0 14.957667291779211 -4.762691535279791 3.3671000513652185 1.0238706614444484 1.3245255061853995 0.7973248953305133 0.03971780375110347 0.14190339849005168 2.4854229712116296 0.00986849406669933 0.11425901063139697 1.7270641318531282e-05 4.762691535279791 0.30065484474095117 EGSTQQLQTT(ph)SPKPLVQQPILPVVK ddPTM_PC-9_Lapatinib_30min_R1 1 EGSTQQLQTTSPKPLVQQPILPVVK 25 1 A0A087X0H9;Q5T8P6-3;Q5T8P6-5;Q5T8P6-4 A0A087X0H9 RBM26 RNA-binding protein 26 1 EGS(0.01)T(0.01)QQLQT(0.148)T(0.416)S(0.416)PKPLVQQPILPVVK 69.05199999999999 0.00041461 9558300.0 41975.0 27462.0 29172.0 25602.0 39003.0 28241.0 30629.0 25185.0 29772.0 29530.0 True False 41376.42880272775 27398.41342626025 26773.590767176447 27484.85648576834 36708.92022284834 27033.198262986403 32214.819751151987 26355.187042362755 26418.763846941358 34634.221153748345 1.194668955281234 0.7910792422509842 0.7730386269788784 0.7935751280144998 1.0599031535858705 0.780534320173696 0.9301441949031813 0.760957982146234 0.7627936464822782 1.0 15.07991061075931 EGSTQQLQTTS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGSTQQLQTTSPK 13 0 A0A087X0H9;Q5T8P6-3;Q5T8P6-2;Q5T8P6;Q5T8P6-5;Q5T8P6-4 A0A087X0H9 RBM26 RNA-binding protein 26 1 EGSTQQLQTT(0.313)S(0.687)PK 143.05 8.423700000000001e-05 7454100.0 28550.0 30085.0 22646.0 30001.0 28665.0 22365.0 30198.0 30191.0 21547.0 21691.0 True False 33382.95111179658 33071.63997516162 23185.96652543327 28320.141234554332 23048.29902342426 21192.14002866765 27337.426825412957 29398.51824000869 21862.08411208087 25623.40659413847 1.3028303238739989 1.2906808411152866 0.9048744724964564 1.105244969302121 0.8995017480890585 0.8270617706825719 1.06689275389583 1.1473305913482168 0.8532075558244457 1.0 14.645174672159373 -5.25192130342311 24.18160699600909 0.9806561939575381 1.2967556766227293 0.6147262783925291 0.1016615835489593 285.94143963787553 726455.7560271428 0.02645906843567609 0.0679166751767271 5.598590418779528e-06 5.25192130342311 0.31609948266519117 EGSTQQLQTTS(ph)PKPLVQQPILPVVK ddPTM_PC-9_AZD4547_30min_R2 1 EGSTQQLQTTSPKPLVQQPILPVVK 25 1 A0A087X0H9;Q5T8P6-3;Q5T8P6-5;Q5T8P6-4 A0A087X0H9 RBM26 RNA-binding protein 26 1 EGS(0.002)T(0.003)QQLQT(0.211)T(0.211)S(0.573)PKPLVQQPILPVVK 48.872 0.014659 12505000.0 51465.0 33748.0 51620.0 57034.0 59055.0 52800.0 52711.0 58100.0 37340.0 48725.0 True False 67829.79946149969 44656.381021890535 50935.4850720912 43885.69246651604 50856.23261350081 49498.407653218776 57402.17688526245 49121.98000518064 39313.71616887914 47019.15258073574 1.4425993608674754 0.9497487421793038 1.083292281472551 0.933357792681625 1.0816067458080298 1.0527286209215692 1.2208254239950032 1.0447227844192677 0.8361213252700432 1.0 15.52096091729438 -4.754384594368424 24.998930393676307 1.0319920196075965 1.4426000717121834 0.619107042996295 0.09860274138137726 171.63525397736663 608144.0052297495 0.024821701199065783 0.24386595210781056 1.760416399368041e-05 4.754384594368424 0.41060805210458695 EGSVLDILKS(ph)PGFASPK ddPTM_PC-9_AZD4547_30min_R2 2 EGSVLDILKSPGFASPK 17 1 P49790-3;P49790 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 EGSVLDILKS(0.945)PGFAS(0.054)PK;EGSVLDILKS(0.986)PGFAS(0.014)PK 78.418 0.0033249000000000004 92059000.0 316410.0 311180.0 359750.0 481870.0 404380.0 339890.0 275210.0 336550.0 275000.0 371050.0 True False 417021.7982631525 411762.8495434361 354979.4799435258 370782.3163172862 348238.81710689055 318636.6245691763 299703.15684758546 284543.9306496305 289535.9385763729 358059.65243882954 1.1646712926818694 1.1499839390973579 0.991397599605753 1.0355322466292964 0.9725720693045224 0.8898981563515084 0.8370201858998519 0.7946830331525321 0.8086248662877114 1.0 18.449840433737776 -5.890200101018297 0.6983976486500574 0.8407418790910807 1.1907745700524566 0.7451780092143467 0.06315409584556689 0.47431472953648923 0.4253012674338253 0.03484443367161838 0.10644612394810117 1.2876561279197649e-06 5.890200101018297 0.3500326909613759 EGSVLDILKS(ph)PGFASPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EGSVLDILKSPGFASPK 17 1 P49790-3;P49790 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 EGSVLDILKS(0.984)PGFAS(0.015)PK;EGSVLDILKS(0.991)PGFAS(0.009)PK 92.773 0.0038465000000000005 26691000.0 18371.9 10606.3 14315.8 20881.6 29905.1 40435.0 40920.0 45907.0 43335.0 36132.8 True False 21481.899808434886 11659.22336940525 14657.142964973824 19711.671651060613 24045.410330556573 38314.517418250674 37043.761364855214 44701.989892487116 43968.692393234545 42683.39061291258 0.5032847554977551 0.2731559794567515 0.3433921896668571 0.4618112893097447 0.5633434922876618 0.897644654468002 0.8678729789954581 1.04729238353815 1.030112457371958 1.0 15.381387162697335 -6.693688993006162 1.2765350788032768 1.0124335876781498 0.36048914871437315 0.9391767487580706 0.07020277310563114 0.09345691413319901 0.32025393156682785 0.032590075956697086 0.031285113825831656 2.0244684221639637e-07 6.693688993006162 -0.6519444389637767 EGSVLDILKS(ph)PGFASPK ddPTM_PC-9_Lapatinib_30min_R1 1 EGSVLDILKSPGFASPK 17 1 P49790-3;P49790 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 EGS(0.002)VLDILKS(0.957)PGFAS(0.041)PK 55.575 0.024428000000000002 21522000.0 25411.0 17790.0 20878.0 20118.0 34647.0 55846.0 59840.0 53551.0 63935.0 56990.0 True False 25048.634480193323 17748.808348014332 19161.491431410603 21597.544831680625 32609.131578622844 53457.59676338437 62938.22240063129 56039.17495753695 56733.967034602836 66840.64556559834 0.3747515343132083 0.26553915208068124 0.2866742424353943 0.32311993172604075 0.48786380356874004 0.7997767871783993 0.9416160162436319 0.8383996666001575 0.8487944207379524 1.0 16.028438046966947 -6.679927836707967 2.1006089646109682 0.8967985016113987 0.3056754745722253 0.9665571620664105 0.05115837736435432 0.051765896953237654 0.46858793518506814 0.019720758890437003 0.01916083386274942 2.0896433215736613e-07 6.679927836707967 -0.5911230270391734 down EGSVLDILKSPGFAS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 EGSVLDILKSPGFASPK 17 1 P49790-3;P49790 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 EGSVLDILKS(0.016)PGFAS(0.984)PK 63.29 0.012256999999999999 20726000.0 30822.0 19589.0 20277.0 21408.0 45627.0 59270.0 64811.0 60257.0 68861.0 57580.0 True False 30382.472627937455 19543.64287404458 18609.903331483514 22982.415734994484 42943.30956613342 56735.16026511823 68166.5964573414 63056.76019899354 61105.14904152321 67532.62627947275 0.4498932486677558 0.28939556997482085 0.2755690746346731 0.3403157407189453 0.6358898199578311 0.8401148213950548 1.009387613258887 0.93372290806585 0.9048241184734845 1.0 16.04329704318879 -6.5683243098728115 1.8529476679326151 0.9546549713464583 0.32384653756436765 0.9616271317969963 0.05665281980611965 0.06076971980539726 0.4241939635324472 0.022354001323756204 0.02352584772272534 2.701939934010053e-07 6.5683243098728115 -0.6308084337820906 down EGT(ph)APSENGETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EGTAPSENGETK 12 0 Q15651;A0A087WZE9 Q15651 HMGN3 High mobility group nucleosome-binding domain-containing protein 3 1 EGT(0.889)APS(0.111)ENGETK;EGT(0.697)APS(0.291)ENGET(0.013)K 117.27 0.0015613 5692100.0 42342.0 62906.0 57375.0 42257.0 65351.0 46018.0 53332.0 45391.0 43744.0 47992.0 True False 49509.66430737974 69150.89194872923 58743.03759589917 39889.477289042436 52545.94067607878 43604.7350699409 48280.00686975706 44199.53434573994 44383.67324448258 56692.56969553703 0.8733007618682216 1.2197522941736216 1.0361681947277046 0.7036103232445755 0.9268576280502473 0.7691437397196261 0.8516108394634611 0.7796354016603949 0.7828834269259904 1.0 15.790872043008902 -5.661724403717502 7.219344485563599 0.824101099012609 1.0654299581391413 0.4293944298077138 0.11156438371255527 0.1765818008296138 11.140451199708096 0.02809460321820863 0.048832960922782186 2.1790921504666856e-06 5.661724403717502 0.24132885912653235 EGT(ph)GQQERESPRPLQLPGAEGPAIS(ph)DGEEGGGEPGAGGGAAGAAGAGR ddPTM_PC-9_AZD4547_30min_R2 1 EGTGQQERESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGR 48 2 Q6PKG0;A0A0B4J210 Q6PKG0 LARP1 La-related protein 1 2 EGT(0.797)GQQERES(0.214)PRPLQLPGAEGPAIS(0.989)DGEEGGGEPGAGGGAAGAAGAGR 43.441 0.0040420000000000005 3984600.0 664.94 740.45 1825.4 2493.2 2303.5 2011.3 784.42 2836.4 2130.6 2515.1 True False 876.3770883888004 979.7859822110593 1801.1940033048274 1918.4312595560154 1983.6987863042782 1885.5330930477076 854.2318603771055 2398.0995539878522 2243.2191662938912 2427.047114536861 0.3610877939450443 0.4036946692722222 0.7421339258379163 0.7904384089066595 0.8173301516986891 0.7768835972545645 0.35196344366809434 0.9880729301151071 0.9242585992080963 1.0 11.244986399434172 -5.266533719735663 3.5720228786636192 0.7859209604452888 0.3661867670728963 0.48575952177626347 0.1718464283097905 0.20301789465438633 5.648920638245069 0.04692428643088638 0.12659313671219835 5.41335215598637e-06 5.266533719735663 -0.4197341933723925 EGT(ph)PPPPPPSR ddPTM_PC-9_AZD4547_30min_R2 1 EGTPPPPPPSR 11 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 EGT(1)PPPPPPSR 103.14 0.007409699999999999 28279000.0 88594.0 77794.0 58276.0 69363.0 65308.0 66569.0 76972.0 54967.0 65347.0 56273.0 True False 116765.0491303235 102939.38915541518 57503.22216313802 53372.43199766724 56241.11149813753 62406.42990657424 83822.35888547779 46473.11316600281 68801.1090114554 54302.89939816813 2.1502544141181255 1.8956518030580107 1.0589346572731595 0.9828652353591957 1.0356926079721405 1.1492283211065426 1.5436074282307195 0.8558127407755055 1.2669877626051098 1.0 15.728741609543848 -5.177663752963296 3.8263233400708674 1.114477591928508 2.093739890173381 0.8050798779474576 0.18076488585412248 0.09432657889417359 2.5683672123588255 0.047431732659655314 0.1440509705487792 6.642571641100925e-06 5.177663752963296 0.9792622982448731 EGT(ph)PPPPPPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EGTPPPPPPSR 11 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 EGT(1)PPPPPPSR;EGT(1)PPPPPPSR;EGT(1)PPPPPPSR 117.95 0.0027186 84358000.0 264678.0 231131.0 132220.0 225677.0 219378.0 158067.0 241943.0 182210.0 179031.0 177482.0 True False 309482.7577712125 254076.1581884352 135372.62624714227 213033.04934470585 176392.45571814943 149777.6882589496 219024.40752436907 177427.1805674534 181648.98968162434 209658.08165326068 1.4761308284936285 1.211859596276544 0.6456828431303969 1.0160974843651713 0.8413339201007904 0.7143902447159504 1.0446742896684456 0.8462692168522663 0.8664058559022844 1.0 17.677678917005387 -5.030098613262822 4.3987125066875175 0.8715589354570439 1.434875888189436 0.7228402900955463 0.12191167907111972 0.08856967991375723 4.052915342516112 0.02980714324033706 0.10311775488337359 9.330424150657388e-06 5.030098613262822 0.563316952732392 EGT(ph)PPPPPPSR ddPTM_PC-9_Lapatinib_30min_R1 3 EGTPPPPPPSR 11 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 EGT(1)PPPPPPSR;EGT(1)PPPPPPSR;EGT(0.996)PPPPPPS(0.004)R 120.57 0.0020857 86869000.0 348643.0 326176.0 194432.0 266791.0 261269.0 215980.0 239467.0 215263.0 192122.0 219246.0 True False 343671.2868867043 325420.7595121934 178446.55148922425 286411.70012868574 245901.6710946174 206743.03887397065 251865.42953897038 225264.904836217 170483.1972256505 257142.37897306817 1.3365019342949251 1.2655275291914303 0.693960101799921 1.113825349491237 0.9562860547400159 0.8040022018137426 0.9794784918177548 0.8760318144984189 0.6629914442982815 1.0 17.972207871056646 -5.154940566362321 6.321544039607062 0.8930754829008231 1.3156073520347593 0.6141511987014637 0.13182048269133453 0.1481456287073295 7.479260461796494 0.03294932727446021 0.08988899667379899 6.999377766386549e-06 5.154940566362321 0.42253186913393626 EGTAPS(ph)ENGETK ddPTM_PC-9_AZD4547_30min_R2 2 EGTAPSENGETK 12 0 Q15651;A0A087WZE9 Q15651 HMGN3 High mobility group nucleosome-binding domain-containing protein 3 1 EGT(0.147)APS(0.847)ENGET(0.005)K;EGT(0.002)APS(0.997)ENGETK 116.58 0.00067043 11275500.0 31660.0 48048.0 41218.0 31835.0 34916.0 40651.0 46564.0 49448.0 43497.0 42378.0 True False 41727.221431090664 63578.57637014916 40671.42238863721 24495.932595847018 30068.51609403089 38109.08654376887 50708.10579357935 41806.94780199947 45796.16261911451 40894.359118859305 1.020366190598822 1.5547028426428755 0.9945484723314987 0.5990051714626381 0.7352729506442895 0.9318910325261474 1.2399780039637356 1.0223157595033519 1.119865027986088 1.0 15.319614234146883 -5.461550388402845 12.063856767591439 0.9411056385666503 1.284657186133858 0.29075732337061133 0.20823141577994733 1.562717229558564 305.05062885210566 0.058160505685320135 0.12101876014011048 3.4550124095959626e-06 5.461550388402845 0.34355154756720774 EGTAPS(ph)ENGETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EGTAPSENGETK 12 0 Q15651;A0A087WZE9 Q15651 HMGN3 High mobility group nucleosome-binding domain-containing protein 3 1 EGTAPS(1)ENGETK;EGTAPS(1)ENGETK 146.96 3.0738000000000004e-07 0.0 29129.0 56403.0 44699.0 36226.0 47492.0 32687.0 36894.0 22496.0 30273.0 27643.2 True False 34059.96437602531 62002.31708555894 45764.79368190152 34196.374666276635 38186.28352417458 30972.836177825142 33399.13323057106 21905.50383648223 30715.685354110745 32654.693336549215 1.043034274583226 1.8987260559008832 1.4014767558903591 1.0472116309235668 1.1693964824784944 0.9484956988757989 1.022797332265516 0.6708225249803278 0.9406208485115918 1.0 14.995002739368703 -6.047754339217265 1.209222355046374 0.9047208372306734 1.5067227363458946 0.4777532180290076 0.22694200109712187 0.3760078380655688 1.1202506768793823 0.08545512777606258 0.15616142668553215 8.95871376247242e-07 6.047754339217265 0.6020018991152212 EGTAPS(ph)ENGETK ddPTM_PC-9_Lapatinib_30min_R1 4 EGTAPSENGETK 12 0 Q15651;A0A087WZE9 Q15651 HMGN3 High mobility group nucleosome-binding domain-containing protein 3 1 EGT(0.001)APS(0.996)ENGET(0.003)K;EGT(0.061)APS(0.938)ENGET(0.001)K;EGT(0.029)APS(0.971)ENGETK;EGTAPS(0.995)ENGET(0.005)K 151.22 5.949e-05 27782600.0 61485.0 115988.0 95479.0 84994.0 113532.0 97676.0 118771.0 120693.0 85882.0 94760.0 True False 60608.21262503191 115719.43691228167 87629.08517959814 91244.74229167242 106854.27097250003 93498.62517387702 124920.38122903359 126300.83739145857 76209.06478244712 111139.139740237 0.5453363483529755 1.0412122784353928 0.7884628708159126 0.8209955781998735 0.9614459066558199 0.8412754083971609 1.1239998934759363 1.1364208656523584 0.685708607791718 1.0 16.76200745286559 -4.751520514426295 24.96240883309626 0.9334738974307751 0.5453355482053267 0.4063647787120168 0.14066668552301298 418.2420876839531 1052499.2969069583 0.035134757297470245 0.4607466867659838 1.7720643375510775e-05 4.751520514426295 -0.38813834922544843 EGTAPS(ph)ENGETKAEEAQK ddPTM_PC-9_Lapatinib_30min_R1 2 EGTAPSENGETKAEEAQK 18 1 Q15651 Q15651 HMGN3 High mobility group nucleosome-binding domain-containing protein 3 1 EGT(0.009)APS(0.985)ENGET(0.006)KAEEAQK;EGT(0.001)APS(0.596)ENGET(0.402)KAEEAQK 59.728 0.013255000000000001 23257000.0 32205.0 61136.0 53255.0 55045.0 67314.0 68537.0 78576.0 80721.0 60468.0 56642.0 True False 31745.750794326294 60994.44334818461 48876.57947024485 59093.19292473711 63354.72286441586 65605.83227755027 82644.28080467926 84471.59234649835 53657.457083731344 66432.49422927908 0.4778648034012074 0.9181417024276393 0.7357330179649233 0.8895224183633423 0.953670693828823 0.9875563613662354 1.2440339891416434 1.271540280498287 0.8076989687989565 1.0 16.01960146143046 -4.393450854879348 0.4666607958507621 1.0958522420582228 6.744218963155055e-11 0.5312105473374311 0.15046225840888705 5.4872916869043875 0.7061132542591828 0.10203569514068893 3.5732021463966097 4.0415610656322165e-05 4.393450854879348 -1.0958522419907806 EGTETFADHR ddPTM_PC-9_AZD4547_30min_R2 1 EGTETFADHR 10 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 115.57 0.00093391 4260200.0 19360.0 22007.0 28888.0 37133.0 32453.0 29409.0 22530.0 36951.0 25627.0 32596.0 False True 25516.07728698404 29120.332379659383 28504.926244916118 28572.56054913106 27947.461129556195 27570.050580937714 24535.12635360671 31241.07199950825 26981.590901442578 31454.823961450216 0.811197586680362 0.9257827166779922 0.906217954990008 0.9083681594959315 0.8884952325216474 0.8764967375028541 0.780011561459571 0.9932044775642702 0.8577886474427625 1.0 14.940993667610263 -9.671941900510168 0.7501953208514497 1.0045804837955379 0.8833855701836942 0.2754636084758264 0.056420434596166906 9.998373713823096 5.24105434868308 0.19656509288980464 0.019088272576104133 2.1284237653813156e-10 9.671941900510168 -0.12119491361184365 EGTETFADHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGTETFADHR 10 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 80.24 0.015046 4267100.0 15721.0 13253.0 18245.0 16558.0 20709.0 17835.0 18717.0 17320.0 18210.0 16663.0 False True 18382.25479609647 14568.670253974306 18680.02999454782 15630.308941760286 16651.220110800372 16899.701203276887 16943.990260654817 16865.36835205693 18476.28680006464 19683.869995764584 0.9338740196948981 0.7401324158871744 0.9490018984359903 0.7940668651603312 0.8459322335690719 0.8585558229612992 0.860805840736638 0.8568116105057533 0.9386511292769267 1.0 14.264726272727117 -8.444706980180245 2.1628109270295273 0.9998704287185509 0.8509766975342592 0.4131289238708995 0.05677671586192796 0.2614775910253819 2.631197129840725 0.04915455786401196 0.013700006692349921 3.591641820891704e-09 8.444706980180245 -0.14889373118429172 EGTETFADHR ddPTM_PC-9_Lapatinib_30min_R1 1 EGTETFADHR 10 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 163.66 0.00059665 5909100.0 54495.0 61430.0 45131.0 56092.0 66480.0 57797.0 55698.0 53063.0 65158.0 49763.0 False True 53717.891306840924 61287.76260924795 41420.50339069795 60217.1927974267 62569.77710470888 55325.15704138752 58581.769907592956 55528.50069600534 57819.21989584189 58364.4682449705 0.9203868881555348 1.0500868842325033 0.7096869831289403 1.0317440492163803 1.0720525515984765 0.9479253166356932 1.0037231841419403 0.9514093482859832 0.9906578717235962 1.0 15.832802716336728 EGTGQQERES(ph)PRPLQLPGAEGPAIS(ph)DGEEGGGEPGAGGGAAGAAGAGR ddPTM_PC-9_Lapatinib_30min_R1 1 EGTGQQERESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGR 48 2 Q6PKG0;A0A0B4J210 Q6PKG0 LARP1 La-related protein 1 2 EGT(0.193)GQQERES(0.825)PRPLQLPGAEGPAIS(0.982)DGEEGGGEPGAGGGAAGAAGAGR 46.73 0.0027102 3778900.0 1606.1 2367.7 2802.8 1887.5 2613.5 2746.3 3939.2 4436.1 3195.3 717.97 True False 1583.1967194773329 2362.2177361210547 2572.3646031208746 2026.3130465154193 2459.779068338697 2628.847150937981 4143.152501346367 4642.217400779246 2835.411665999317 842.0701578651103 1.8801244821348273 2.8052505056228987 3.0548103137184643 2.406347057414675 2.9211094175038137 3.1218861354769576 4.92019870630548 5.51286298109483 3.3671917232976165 1.0 9.7177966275646 -7.0424840504115105 4.931580749838868 4.080915087583111 2.6639969792812286 0.12834835413567347 1.1700891970161202 0.2953543127233222 16.895972458933514 0.4317650320566541 0.3423162452337966 9.068092668008721e-08 7.0424840504115105 -1.416918108301882 EGTGQQERES(ph)PRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGR ddPTM_PC-9_AZD4547_30min_R2 1 EGTGQQERESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGR 48 2 Q6PKG0;A0A0B4J210 Q6PKG0 LARP1 La-related protein 1 1 EGT(0.138)GQQERES(0.862)PRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGR 65.8 6.5551e-11 10242000.0 10885.0 7329.1 9549.7 14143.0 15597.0 13673.0 8701.5 13549.0 10027.0 9049.7 True False 14346.203577934986 9698.088246637953 9423.064738336865 10882.549857171805 13431.625773817155 12818.025148531451 9475.91664296089 11455.313375046335 10557.00674947379 8732.872757514306 1.6427817026866243 1.110526686455281 1.0790337841838673 1.2461592146533664 1.5380535302383458 1.4677902111309278 1.085085848160014 1.311746282480696 1.208881320340994 1.0 13.092240604182011 -8.869965150185827 0.833050534036384 0.9995011645895904 1.3101312171683714 0.21741663027351454 0.18236617176728945 2.1060909444111076 2.6698701674038805 0.18920033187453586 0.06442583296550454 1.3490711340062796e-09 8.869965150185827 0.31063005257878107 EGTGQQERES(ph)PRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EGTGQQERESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGR 48 2 Q6PKG0;A0A0B4J210 Q6PKG0 LARP1 La-related protein 1 1 EGT(0.281)GQQERES(0.713)PRPLQLPGAEGPAIS(0.007)DGEEGGGEPGAGGGAAGAAGAGR;EGT(0.236)GQQERES(0.704)PRPLQLPGAEGPAIS(0.059)DGEEGGGEPGAGGGAAGAAGAGR 60.802 2.0222999999999998e-07 14062700.0 6855.6 8880.7 7963.7 9094.4 10824.5 7622.099999999999 9252.1 8486.1 8938.1 5380.700000000001 True False 8016.117675727943 9762.317205498355 8153.584810500436 8584.870252442617 8703.516929323414 7222.383658059812 8375.674108596702 8263.348866766173 9068.802803276094 6356.1783164022345 1.2611536801983991 1.5358784350505896 1.2827810052874007 1.3506339540993055 1.3693003084674056 1.1362776968390453 1.317721701888558 1.300049881458242 1.4267697273177316 1.0 12.633943883322818 -6.638767783679815 22.67208338774021 1.259194483032716 1.3649438652948431 0.17946959697218712 0.12744964683542812 8.04749328485577 1543.2857988826818 0.04034373449139314 0.040343718236729234 2.2973767221234157e-07 6.638767783679815 0.10574938226212716 EGTGSTATS(ph)SSSTAGAAGK ddPTM_PC-9_Lapatinib_30min_R1 1 EGTGSTATSSSSTAGAAGK 19 0 E5RHC7;E5RH59;E5RFW7;E5RFH0;E5RGU4;A0A087WZK9;B3KS98;O15372 E5RHC7 EIF3H Eukaryotic translation initiation factor 3 subunit H 1 EGTGSTAT(0.004)S(0.654)S(0.007)S(0.167)S(0.167)T(0.001)AGAAGK 344.29 8.831499999999994e-223 1698200.0 16471.0 16708.0 14916.0 15875.0 13928.0 14976.0 13735.0 11163.0 14741.0 11088.0 True False 16236.120519588536 16669.313652536464 13689.664057425061 17042.50045744756 13108.782423501567 14335.511390761107 14446.131094128848 11681.673732535057 13080.713350388367 13004.546026168702 1.2484957557854786 1.281806655841215 1.0526829640863828 1.310503298089252 1.00801538147684 1.102346161251161 1.1108523946210258 0.8982761650447725 1.005856976788455 1.0 13.666728416875207 -6.439848764404899 0.5277456455636709 0.9645610418614522 1.273266318777268 0.5408982592623772 0.08828188730124348 0.8341317534599177 0.483331642639653 0.07110284984027793 0.12477022886236348 3.6320451248455227e-07 6.439848764404899 0.30870527691581573 EGTGSTATSSSS(ph)TAGAAGK ddPTM_PC-9_AZD4547_30min_R2 1 EGTGSTATSSSSTAGAAGK 19 0 E5RHC7;E5RH59;E5RFW7;E5RFH0;E5RGU4;A0A087WZK9;B3KS98;O15372 E5RHC7 EIF3H Eukaryotic translation initiation factor 3 subunit H 1 EGTGSTAT(0.052)S(0.232)S(0.051)S(0.051)S(0.577)T(0.038)AGAAGK 108.96 0.00017366 1825800.0 6655.2 9034.1 11526.0 15766.0 11433.0 11430.0 9231.1 12531.0 9570.8 11026.0 True False 8771.41516324051 11954.196153545727 11373.157709045383 12131.392282271847 9845.725297945211 10715.280293111571 10052.65001698974 10594.621883733535 10076.692948824548 10639.983096053204 0.8243824340749357 1.123516461034606 1.0689074979136144 1.1401702589895906 0.925351592108956 1.0070768154778647 0.9447994349463461 0.9957367213923023 0.9470591125809587 1.0 13.377208238352877 -6.286684059006046 24.956106755631765 0.9703842036301727 1.0473824541070007 0.13719157013721062 0.08407798743488422 1375.888955694958 1360157.364266059 0.025473332657314655 0.02889521644268218 5.167921890649628e-07 6.286684059006046 0.07699825047682796 EGTGSTATSSSSTAGAAGK ddPTM_PC-9_Lapatinib_30min_R1 2 EGTGSTATSSSSTAGAAGK 19 0 E5RHC7;E5RH59;E5RFW7;E5RFH0;E5RGU4;A0A087WZK9;B3KS98;O15372 E5RHC7 EIF3H Eukaryotic translation initiation factor 3 subunit H 0 ; 281.54 4.752299999999998e-202 0.0 7243.6 7530.599999999999 5381.1 5890.799999999999 9062.6 6757.6 8272.900000000001 5344.5 6043.8 7358.9 False True 7140.304935686447 7513.163358378689 4938.68672964669 6324.029083132733 8529.555685757132 6468.593200734988 8701.230282389419 5592.824981056488 5363.083599964535 8630.876059882105 0.8272978184538988 0.8704983487483097 0.5722115223740278 0.7327215730194505 0.9882607080182824 0.7494712188954024 1.0081514578611936 0.6480020037656391 0.6213834566450481 1.0 13.075291289385099 EGTLTQVPLAPPPPGAPPS(ph)PAPAR ddPTM_PC-9_AZD4547_30min_R2 1 EGTLTQVPLAPPPPGAPPSPAPAR 24 0 P48634 P48634 PRRC2A Protein PRRC2A 1 EGTLTQVPLAPPPPGAPPS(1)PAPAR 100.66 1.9224e-06 4319200.0 22213.0 17977.0 25117.0 38281.0 35857.0 29986.0 29853.0 39035.0 27845.0 32053.0 True False 29276.27194089757 23787.713690604658 24783.932168843756 29455.906885554276 30878.87448687322 28110.97067972384 32509.859167075978 33003.0376850641 29316.82985330582 30930.834226173905 0.9465076734375231 0.7690614975549322 0.8012694383739384 0.952315306795976 0.9983201313317079 0.9088332527396278 1.0510501892498552 1.0669947484680733 0.9478189187829178 1.0 14.916758123992917 -5.893981458391616 4.287814029910278 0.9957755081894285 0.8326212813146427 0.5730415667729463 0.06023384653592719 0.15131344670659583 4.957576722544459 0.01761337104089368 0.026955265463254396 1.2764933057822518e-06 5.893981458391616 -0.16315422687478576 EGTLTQVPLAPPPPGAPPS(ph)PAPAR ddPTM_PC-9_Lapatinib_30min_R1 1 EGTLTQVPLAPPPPGAPPSPAPAR 24 0 P48634 P48634 PRRC2A Protein PRRC2A 1 EGTLTQVPLAPPPPGAPPS(1)PAPAR 100.58 1.9459e-06 3694500.0 10820.0 11262.0 12931.0 9657.8 10114.0 9009.1 7459.4 9114.0 11383.0 7255.0 True False 10665.704815855011 11235.923530935215 11867.86309510349 10368.066829476345 9519.11440488906 8623.801794237841 7845.611232875488 9537.4697122928 10100.926671696003 8509.017083320154 1.2534590906818739 1.3204725552802679 1.3947396014009106 1.2184799640137525 1.1187090484926814 1.0134897732362877 0.9220349608011588 1.1208662080357876 1.1870850149656413 1.0 13.0547767736921 -6.201603706764767 2.3559011724017447 1.0507392910090951 1.3212693700913725 0.7138100554640118 0.07573415898012334 0.1720271687873204 1.8746154915301247 0.026529920045704432 0.035300425166840066 6.286317229295739e-07 6.201603706764767 0.27053007908227733 EGTPGS(ph)PGR ddPTM_PC-9_AZD4547_30min_R2 1 EGTPGSPGR 9 0 Q99856 Q99856 ARID3A AT-rich interactive domain-containing protein 3A 1 EGTPGS(1)PGR 73.84100000000001 0.028506999999999998 15971000.0 48196.0 52567.0 77722.0 82140.0 90297.0 92911.0 91034.0 87686.0 64348.0 59299.0 True False 63521.32546092373 69558.25474628774 76691.35549734738 63203.89205034943 77760.82018967545 87101.26048235229 99135.84964377429 74136.14352382565 67749.30391095433 57222.96005921088 1.1100671023518474 1.2155654771146587 1.3402199994196695 1.1045197938895477 1.3589094326685167 1.5221383233622505 1.7324488202147261 1.29556638536549 1.183953151686865 1.0 15.804306507624561 -6.411971954520159 6.493355621569832 1.394705103839172 1.2056971461181707 0.10940437804249403 0.1944329386550211 0.45621686962919245 23.406261034574698 0.06219505440575207 0.07043694837907866 3.872826537062422e-07 6.411971954520159 -0.18900795772100132 EGTPGS(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 1 EGTPGSPGR 9 0 Q99856 Q99856 ARID3A AT-rich interactive domain-containing protein 3A 1 EGTPGS(1)PGR 90.149 0.008796600000000002 14160000.0 37720.0 38108.0 47399.0 42637.0 39018.0 41388.0 36889.0 38179.0 42584.0 35798.0 True False 37182.10588299919 38019.763267348564 43502.03718543113 45772.66721286248 36723.03795233947 39617.93172014027 38798.931920736744 39952.9357192919 37787.74149060022 41985.636602163344 0.8855910947669983 0.9055421411757173 1.0361171273318184 1.0901982419984078 0.8746571666951285 0.9436067885677579 0.9241001223436873 0.9515858029703732 0.9000159232706068 1.0 15.357608242037246 EGTQASEGYFSQS(ph)QEEEFAQSEELCAK ddPTM_PC-9_AZD4547_30min_R2 1 EGTQASEGYFSQSQEEEFAQSEELCAK 27 0 Q16643-3;Q16643;Q16643-2 Q16643-3 DBN1 Drebrin 1 EGTQASEGY(0.001)FS(0.039)QS(0.926)QEEEFAQS(0.034)EELCAK 69.47 0.00013388 1504700.0 3804.2 4709.3 5488.2 7157.0 6778.3 5895.5 5328.9 5779.6 4214.1 5919.3 True False 5013.85646772442 6231.489129619204 5415.4228820738235 5507.064224547737 5837.2500469747265 5526.8534530218085 5803.161776552808 4886.495621995559 4436.8487227443375 5712.0671086947 0.8777656796245462 1.0909341593928157 0.9480670970813113 0.9641105609850213 1.021915523031842 0.9675750210653221 1.0159477586878218 0.8554688747542047 0.7767501043520179 1.0 12.479797213751143 -7.767865588865343 24.960717548872623 0.8620820704924386 0.9865980702322151 0.3004321496858422 0.07316971923623995 153.7896629704177 597337.8106222238 0.03607176644111604 0.017982879073551675 1.7066104914056926e-08 7.767865588865343 0.12451599973977656 EGVHGGLINK ddPTM_PC-9_AZD4547_30min_R2 2 EGVHGGLINK 10 0 P07737;K7EJ44 P07737 PFN1 Profilin-1 0 ; 101.66 0.0029498000000000003 42152000.0 311140.0 391470.0 412780.0 372460.0 374160.0 411470.0 346560.0 465000.0 378010.0 359440.0 False True 410076.0478859615 518005.0218869113 407306.26749433944 286595.1014496367 322214.34247172094 385740.71585359785 377403.1686243203 393144.93463698734 397990.83687729045 346856.11500502145 1.1822655854864337 1.4934291179482655 1.1742801982558182 0.8262650968269296 0.9289567879380077 1.1121058535987278 1.088068372728146 1.1334525113714538 1.1474234406146442 1.0 18.403977793672567 -5.519890603877761 24.978929345275567 1.0373824882522604 1.3368492130146081 0.5227224450431845 0.11645969309616148 87.61211072725276 732378.8819191747 0.03282566949234654 0.05829415286233008 3.0207125235759904e-06 5.519890603877761 0.2994667247623477 EGVHGGLINK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EGVHGGLINK 10 0 P07737;K7EJ44 P07737 PFN1 Profilin-1 0 ; 110.53 0.0014484 34776000.0 282847.0 425970.0 338270.0 351160.0 403950.0 271072.0 339510.0 265924.0 253536.0 257152.0 False True 330727.41061710456 468257.48646234424 346335.63969611825 331485.6436760812 324798.89727933874 256856.50712501656 307349.1549604591 258943.77676976848 257243.48435701203 303771.62198588863 1.0887370204464593 1.5414787049597958 1.1401184792442753 1.0912330832913681 1.0692206703048348 0.8455579406852841 1.0117770480046244 0.8524291211830097 0.8468318491217128 1.0 18.212627575572093 -6.01624931251488 1.1584496162965716 0.9084408733328618 1.3145915524527034 0.5814237600323376 0.12600170351147952 0.3207842534253564 0.8768026246428133 0.04689390961080309 0.09084371963935063 9.632758835569509e-07 6.01624931251488 0.4061506791198416 EGVHGGLINK ddPTM_PC-9_Lapatinib_30min_R1 2 EGVHGGLINK 10 0 P07737;K7EJ44 P07737 PFN1 Profilin-1 0 ; 120.45 0.00059153 84817000.0 420970.0 480370.0 464760.0 461910.0 475970.0 468200.0 522860.0 516760.0 421460.0 476120.0 False True 414966.8906035561 479257.7327788445 426549.2268254803 495880.402286589 447974.38039302436 448176.1774275073 549931.1324263723 540770.5561251295 373990.7366294473 558416.7076099792 0.7431133147495038 0.8582438996678041 0.7638547002848624 0.8880113999614279 0.8022223803266069 0.8025837538882015 0.9848042240356217 0.9683996713487044 0.6697341457244821 1.0 19.090982581502765 -7.223419288264543 24.546244873776427 0.9031011948251624 0.813019103997548 0.19682671684400044 0.0948616841651327 786.5068340831543 507779.02509563067 0.035173186721595265 0.027244379483194248 5.978341392327195e-08 7.223419288264543 -0.09008209082761442 EGVHGGLINKK ddPTM_PC-9_AZD4547_30min_R2 1 EGVHGGLINKK 11 1 P07737;K7EJ44 P07737 PFN1 Profilin-1 0 61.353 0.023683000000000003 53207000.0 561750.0 466750.0 629150.0 880850.0 826240.0 663370.0 610410.0 706510.0 533930.0 706160.0 False True 740374.8148741364 617617.8097062751 620807.059920693 677783.6414968391 711530.8379405459 621889.3690324946 664735.3074791424 597335.1134846854 562152.4497603006 681437.553338376 1.0864896001798339 0.9063454261957729 0.9110256059111316 0.9946379358994286 1.044161470782968 0.9126138792701494 0.9754896897339912 0.8765808555139484 0.8249507926387454 1.0 19.378221929534952 -7.758271326546226 24.968071791640263 0.8880743559334383 0.9715798212068794 0.19390985941782712 0.06860224173058052 116.3911917489205 917328.575453154 0.03321108836738441 0.018134287283905773 1.7447317868744684e-08 7.758271326546226 0.08350546527344105 EGVHGGLINKK ddPTM_PC-9_Lapatinib_30min_R1 2 EGVHGGLINKK 11 1 P07737;K7EJ44 P07737 PFN1 Profilin-1 0 ; 112.71 0.0029023000000000005 89066000.0 1241199.0 975830.0 1106932.0 1110856.0 1117031.0 1041882.0 1028027.0 909775.0 1239371.0 949151.0 False True 1223499.2746519784 973570.5255898174 1015924.3238410866 1192552.0559469846 1051329.4327474432 997323.1356055669 1081253.2078852563 952046.4677969274 1099779.9868247872 1113210.4856857916 1.0990727183981235 0.8745610449312745 0.9126075768278701 1.0712727478598216 0.9444120822305886 0.8958980789613813 0.971292690635367 0.8552259254101624 0.9879353464293588 1.0 20.086294972376585 -6.502544188669254 24.524070899720865 0.9332158162614415 0.979712228919944 0.07652379331960191 0.07387103629803 1653.3613525221306 1994005.5433899513 0.022625046634007974 0.025327962026833954 3.1438065274203487e-07 6.502544188669254 0.04649641265850257 EGVIEAGAFQGSPAPPLPS(ph)VMSPSR ddPTM_PC-9_AZD4547_30min_R2 1 EGVIEAGAFQGSPAPPLPSVMSPSR 25 0 P53367 P53367 ARFIP1 Arfaptin-1 1 EGVIEAGAFQGSPAPPLPS(0.499)VMS(0.387)PS(0.114)R 120.63 2.8076999999999997e-09 9264400.0 21347.0 21105.0 32689.0 37608.0 32914.0 32019.0 29320.0 40201.0 27633.0 28463.0 True False 28134.90195481654 27926.77851923075 32255.52250138682 28938.056637807902 28344.459236995444 30016.84686834116 31929.423199633784 33988.859177078586 29093.623966112413 27466.519033462948 1.024334460458542 1.0167571101822936 1.1743578595485413 1.053575686185503 1.0319640141680453 1.0928522406414551 1.162485248339391 1.237465116554062 1.0592395756690949 1.0 14.74538646173691 -7.025671432489765 6.405181794571046 1.1339524274811343 1.063517537189103 0.0900095798581605 0.07222324051711956 0.3339667552464608 49.658308130448134 0.027001365844516106 0.02167112702660452 9.426024571029142e-08 7.025671432489765 -0.07043489029203132 EGVIEAGAFQGSPAPPLPS(ph)VMSPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EGVIEAGAFQGSPAPPLPSVMSPSR 25 0 P53367 P53367 ARFIP1 Arfaptin-1 1 EGVIEAGAFQGSPAPPLPS(0.554)VMS(0.336)PS(0.109)R;EGVIEAGAFQGSPAPPLPS(0.565)VMS(0.323)PS(0.112)R 126.3 1.6595e-09 10583700.0 42367.0 36410.0 43726.0 53687.0 65119.0 63460.0 74001.0 59214.0 55431.0 43771.0 True False 49538.89631360724 40024.54417469288 44768.59367177847 50679.0914456024 52359.39941065285 60132.045885054766 66991.08955915582 57659.69524241908 56241.57350985079 51706.335808954645 0.9580817425671838 0.7740742705608877 0.865824138790073 0.9801331046325207 1.0126302433054075 1.1629531457659572 1.2956069795136038 1.115137909896787 1.0877114502495981 1.0 15.658053450807536 -6.264558288435648 1.6112299903764087 1.1467727495130395 0.859213777304737 0.6379707947022816 0.08506738677881068 0.22613186557087045 1.1656953434707897 0.031524445539202556 0.04249693053542528 5.438031407824299e-07 6.264558288435648 -0.2875589722083025 EGVIEAGAFQGSPAPPLPS(ph)VMSPSR ddPTM_PC-9_Lapatinib_30min_R1 1 EGVIEAGAFQGSPAPPLPSVMSPSR 25 0 P53367 P53367 ARFIP1 Arfaptin-1 1 EGVIEAGAFQGSPAPPLPS(0.551)VMS(0.338)PS(0.111)R 110.91 1.5934000000000002e-07 6177500.0 42440.0 47063.0 49906.0 45725.0 52401.0 57062.0 54254.0 57721.0 62489.0 46000.0 True False 41834.79781745719 46954.02851504211 45802.921322730974 49087.76903412848 49318.87620432985 54621.59127801887 57063.006653139215 60402.92838087035 55450.83078165789 53951.0387088528 0.7754215455094202 0.870308146770443 0.8489720016310862 0.9098577193115968 0.9141413656645156 1.0124289093447247 1.057681335128322 1.1195878675633146 1.0277991324856361 1.0 15.719363115457092 -6.513601500654193 1.0235040622091978 1.0656612203604734 0.8292888157079237 0.8472277300419332 0.03959224233685571 0.18245481209537026 0.41034813374284795 0.0195619509592306 0.022985501589640585 3.0647743153796786e-07 6.513601500654193 -0.23637240465254972 EGVIEAGAFQGSPAPPLPSVMS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 1 EGVIEAGAFQGSPAPPLPSVMSPSR 25 0 P53367 P53367 ARFIP1 Arfaptin-1 1 EGVIEAGAFQGSPAPPLPS(0.208)VMS(0.584)PS(0.208)R 113.52 1.6691e-08 5190600.0 20409.0 21957.0 26215.0 27883.0 24068.0 26520.0 30026.0 30642.0 29266.0 24859.0 True False 20117.963917447767 21906.159915534066 24059.703892826372 29933.608834961302 22652.3675595086 25385.801421139444 31580.599361653643 32065.73918412066 25969.75489535758 29155.84502746463 0.6900147774313098 0.7513471104987215 0.8252103092934633 1.0266760852502825 0.7769408685692425 0.8706933857422473 1.083165290935828 1.0998048300062964 0.8907220789139957 1.0 14.831497516725385 -3.612747688076234 0.34135491508122756 1.022195854005201 4.794234021729768e-12 0.5423379030217784 0.09260259419504853 11.878118497567016 0.5946494783152971 0.09039937246832352 5.8547226452752 0.0002439227524017929 3.612747688076234 -1.0221958540004068 EGVIEAGAFQGSPAPPLPSVMSPS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 EGVIEAGAFQGSPAPPLPSVMSPSR 25 0 P53367 P53367 ARFIP1 Arfaptin-1 1 EGVIEAGAFQGSPAPPLPS(0.036)VMS(0.356)PS(0.608)R 135.86 4.8354e-07 7240900.0 22600.0 19942.0 25948.0 43185.0 30964.0 31161.0 25636.0 36180.0 33545.0 31488.0 True False 29786.32989079751 26387.86151293531 25603.91256587799 33229.365451598984 26665.18307754532 29212.497743976346 27917.554336487447 30589.21233369079 35318.1202165252 30385.614704201278 0.9802773510018573 0.8684327031003517 0.8426327002144819 1.093588718710519 0.8775594417663187 0.9613923571517304 0.9187753681556232 1.0067004611054111 1.1623302855756257 1.0 14.891100857601005 -7.98858910504518 4.656246664476262 1.0839152428640513 0.9343993245476643 0.37467723563445354 0.07600713776167137 0.18423138193297486 10.377533415175904 0.04659465651224697 0.019511662882763098 1.026622775862948e-08 7.98858910504518 -0.149515918316387 EGVNQPAAVVMEDS(ph)SPHEALR ddPTM_PC-9_Lapatinib_30min_R1 2 EGVNQPAAVVMEDSSPHEALR 21 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 EGVNQPAAVVMEDS(0.965)S(0.035)PHEALR;EGVNQPAAVVMEDS(0.87)S(0.13)PHEALR 161.51 1.9235e-06 7391900.0 35874.0 35145.0 51547.0 40315.0 40983.0 35050.0 36249.0 32195.0 40811.0 29635.0 True False 35362.43018151409 35063.62391180235 47309.00463717417 43279.89958689753 38572.46051567814 33550.99320554066 38125.79585228082 33690.89723362591 36214.43542111792 34757.37026384464 1.017408104038839 1.0088111858185163 1.361121519782698 1.2452006368248811 1.109763489667745 0.9652914748973722 1.0969125558943706 0.9693166363817778 1.0419210413852555 1.0 15.085031311792967 -6.566302919555724 6.056762686945408 1.0189143298735548 1.16395528557714 0.3094637944982408 0.10167676059769458 0.2554981656323535 23.199774248752593 0.03645936230297477 0.0367596591322327 2.7145452183619717e-07 6.566302919555724 0.14504095570358522 EGVNQPAAVVMEDSS(ph)PHEALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGVNQPAAVVMEDSSPHEALR 21 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 EGVNQPAAVVMEDS(0.273)S(0.727)PHEALR 96.41 0.00032512 0.0 25016.0 31499.0 29721.0 31191.0 34924.0 32119.0 37701.0 33845.0 33621.0 29086.0 True False 29250.714711478246 34626.012550361185 30429.661357520166 29443.46939258638 28080.892904031687 30434.623097732023 34129.68834839704 32956.60461174169 34112.64352031701 34359.06155535067 0.8513246109576321 1.0077694495404208 0.8856371501444984 0.856934621021429 0.8172776447574047 0.88578155863493 0.9933242295752425 0.9591823268703165 0.9928281500169411 1.0 15.06840301241899 -7.257421817900446 23.706917167810076 0.9829322088884652 0.8855360821333826 0.5248142511044103 0.04759205849598308 156.72713142180285 924824.5493001257 0.020085477845422542 0.014958316865978592 5.528129168865879e-08 7.257421817900446 -0.09739612675508258 EGVQGPLNVS(ph)LSEEGK ddPTM_PC-9_AZD4547_30min_R2 3 EGVQGPLNVSLSEEGK 16 0 P12270 P12270 TPR Nucleoprotein TPR 1 EGVQGPLNVS(0.991)LS(0.009)EEGK;EGVQGPLNVS(0.94)LS(0.06)EEGK;EGVQGPLNVS(0.998)LS(0.002)EEGK 223.86 1.4780000000000002e-28 28489100.0 120062.0 155850.0 138490.0 135991.0 126476.0 162279.0 160441.0 157686.0 148983.0 148255.0 True False 158239.21855526202 206225.46468714112 136653.53211224152 104640.37599000565 108916.99053467304 152131.66847645235 174719.93818459925 133319.25196380244 156857.93722517745 143064.63757530987 1.1060680070011304 1.441484549797172 0.955187350475106 0.7314202710290478 0.7613131545336537 1.0633771633215061 1.2212657239817624 0.9318812406987896 1.0964130611424274 1.0 17.126307588154937 -5.281946486388372 24.003486685374543 0.9639939457430726 1.2737762607105847 0.37308069084689555 0.15729844387028993 460.44223161321224 538945.4518013704 0.0444019972269912 0.09262975139263481 5.224605624377226e-06 5.281946486388372 0.3097823149675121 EGVQGPLNVS(ph)LSEEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EGVQGPLNVSLSEEGK 16 0 P12270 P12270 TPR Nucleoprotein TPR 1 EGVQGPLNVS(0.987)LS(0.013)EEGK;EGVQGPLNVS(1)LSEEGK;EGVQGPLNVS(0.997)LS(0.003)EEGK;EGVQGPLNVS(0.997)LS(0.003)EEGK 194.67 9.1648e-12 33391400.0 115769.0 152288.0 133439.0 143499.0 139925.0 106970.0 154960.0 120759.0 106718.0 101997.0 True False 135366.4051580238 167406.14620366986 136620.6918302256 135459.2162600348 112507.7007100168 101360.30489007737 140281.0669867538 117589.204204737 108278.54885937923 120488.24869219198 1.1234822202772705 1.3893981199057657 1.1338922535030511 1.1242525120112645 0.9337649267144478 0.841246395314615 1.164271773466689 0.9759391930837913 0.8986648078518882 1.0 16.878532920641277 -5.87187185926418 2.007885332212047 0.9730868403689159 1.2494352701861333 0.53905447811852 0.10373527973002312 0.2432344922477591 1.9986000045392756 0.03234245278892011 0.05740601006705035 1.343161209038365e-06 5.87187185926418 0.2763484298172174 EGVQGPLNVS(ph)LSEEGK ddPTM_PC-9_Lapatinib_30min_R1 4 EGVQGPLNVSLSEEGK 16 0 P12270 P12270 TPR Nucleoprotein TPR 1 EGVQGPLNVS(0.991)LS(0.009)EEGK;EGVQGPLNVS(1)LSEEGK;EGVQGPLNVS(0.994)LS(0.006)EEGK;EGVQGPLNVS(1)LSEEGK 191.4 1.4557e-08 44309500.0 165979.0 213363.0 185456.0 197587.0 207713.0 212657.0 210712.0 181420.0 180565.0 155504.0 True False 163612.10902317916 212868.9710824832 170208.52356086246 212118.20711090928 195495.72971947008 203562.15583767905 221621.63633826558 189849.43550627187 160227.8682662556 182382.65920394452 0.8970814974258288 1.1671557592788915 0.9332494893088018 1.1630393373841192 1.0718986693842545 1.116126701552537 1.215146425134876 1.0409401657751782 0.87852578181287 1.0 17.47660904017983 -8.013615385968452 23.97981531766016 0.9460861788668316 1.0856660726216398 0.24157419245810918 0.09837469611395251 495.07993895683455 871941.9217236979 0.05860952865358547 0.02426088079048085 9.691357492807926e-09 8.013615385968452 0.13957989375480828 EGVQGPLNVSLS(ph)EEGK ddPTM_PC-9_AZD4547_30min_R2 1 EGVQGPLNVSLSEEGK 16 0 P12270 P12270 TPR Nucleoprotein TPR 1 EGVQGPLNVS(0.109)LS(0.891)EEGK 199.91 3.3979e-12 14002000.0 68175.0 81045.0 69146.0 67500.0 65062.0 76839.0 87017.0 87754.0 73585.0 71602.0 True False 89853.23187190789 107241.21132864515 68229.07886080627 51938.91786460414 56029.264351868434 72034.245183062 94761.34442573454 74193.63568631001 77474.55287324508 69095.23577395246 1.3004258667828554 1.5520782312616836 0.987464303385839 0.7517004216401283 0.8108990978071221 1.042535630368563 1.371459889589923 1.0737880094806702 1.121271995173529 1.0 16.07629861748208 -5.269729054910342 24.73857776266802 1.018847882511845 1.426252052998324 0.4801706528132508 0.16912142974531993 445.85343606316803 1330547.4389117982 0.04989812471314643 0.10675259745915859 5.373669411452301e-06 5.269729054910342 0.40740417048647903 EGVS(ph)STTPAKDAASAGLGSIGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGVSSTTPAKDAASAGLGSIGVK 23 1 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 EGVS(0.25)S(0.25)T(0.25)T(0.25)PAKDAASAGLGSIGVK 62.325 0.0016547 8528200.0 13924.0 11920.0 10010.0 16714.0 19675.0 15078.0 19304.0 15301.0 12350.0 12548.0 True False 16281.058188464305 13103.338823464406 10248.676363136403 15777.56876751911 15819.824988169263 14287.283136697999 17475.385371142835 14899.364962749582 12530.595386095461 14822.853070086647 1.0983754687092189 0.8839957302084902 0.6914105074561394 1.0644083627435486 1.0672591108721547 0.9638686337335787 1.1789488358627225 1.0051617520797895 0.8453565131386824 1.0 13.8555355406824 EGVSSTT(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 1 EGVSSTTPAK 10 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 EGVSS(0.004)T(0.004)T(0.992)PAK 115.57 0.0027206999999999995 3532700.0 37264.0 42230.0 48311.0 35646.0 43254.0 53823.0 40826.0 53696.0 38406.0 37416.0 True False 49113.17686064947 55880.02164734016 47670.364574153355 27428.365425210097 37248.92871838733 50457.4393014999 44459.43490955825 45398.51701132838 40436.06275259703 36106.07722854406 1.3602468235408998 1.5476624971921233 1.3202864512921115 0.7596606314109996 1.0316526074712922 1.397477742655749 1.2313560021527443 1.2573649783100247 1.119924008821148 1.0 15.139954065680707 -5.529640903279666 24.996027082419747 1.1303886965653667 1.4489596876891704 0.40879672876082285 0.167201968827899 168.23542154340174 621873.2859958735 0.04879368761080738 0.08476384980010335 2.9536504453668406e-06 5.529640903279666 0.3185709911238037 EGVSSTT(ph)PAKDAASAGLGSIGVK ddPTM_PC-9_AZD4547_30min_R2 1 EGVSSTTPAKDAASAGLGSIGVK 23 1 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 EGVS(0.065)S(0.186)T(0.186)T(0.559)PAKDAAS(0.003)AGLGS(0.001)IGVK 44.541000000000004 0.045107 11742000.0 21113.0 18637.0 22026.0 24413.0 29424.0 27237.0 20261.0 28168.0 22144.0 27592.0 True False 27826.494822318906 24661.045783601203 21733.920848467256 18784.960027090103 25338.985495210352 25533.866084293935 22064.18974924216 23815.28283624661 23314.486632128024 26626.012478351175 1.045086824207861 0.9262012403716994 0.8162664562009977 0.7055115760335349 0.9516627965157282 0.9589819769315728 0.8286704502667045 0.8944367037914563 0.8756281719271463 1.0 14.700548765722619 EGVSSTT(ph)PAKDAASAGLGSIGVK ddPTM_PC-9_Lapatinib_30min_R1 1 EGVSSTTPAKDAASAGLGSIGVK 23 1 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 EGVS(0.051)S(0.181)T(0.181)T(0.587)PAKDAAS(0.001)AGLGSIGVK 52.095 0.015667 9184600.0 23284.0 16136.0 21186.0 18011.0 12622.0 18406.0 11841.0 12526.0 15318.0 11073.0 True False 22951.96589023735 16098.638083392894 19444.16886032499 19335.58902293468 11879.59877580678 17618.81828648164 12454.069041542034 13108.00368841119 13592.725534309002 12986.953296154948 1.767309496449236 1.239600829869714 1.4972078837060137 1.4888471977996083 0.9147333100307659 1.3566552435125836 0.958967723802419 1.0093209230445206 1.0466446767259419 1.0 13.664775397704759 -5.49179968380663 0.4249553241413002 0.9682521974734143 1.8379340624701865 0.6054555389234876 0.17216479040671753 2.118580704339286 0.4659646035841821 0.14290866500440624 0.8817781053911651 3.2225548361072203e-06 5.49179968380663 0.8696818649967722 EGYAWAEDKEHCEEYGR ddPTM_PC-9_AZD4547_30min_R2 2 EGYAWAEDKEHCEEYGR 17 1 Q9Y3I0 Q9Y3I0 RTCB tRNA-splicing ligase RtcB homolog 0 ; 82.663 0.0019416000000000001 19916200.0 51010.0 50037.0 57109.0 81492.0 75342.0 55904.0 60534.0 82409.0 56893.0 63219.0 False True 67230.11892608758 66210.48172313417 56351.69734564231 62705.27843884922 64882.063797584924 52408.314042529244 65921.4087301034 69674.58262042918 59900.24783063849 61005.72205236598 1.1020297222017752 1.0853159260421594 0.9237116691655783 1.0278589668199383 1.0635406256136364 0.8590721047042619 1.0805774690039387 1.1420991388417965 0.9818791715836331 1.0 15.896656946641555 -10.287980205468806 9.709241030412379 0.9999999034695176 1.0288361847691487 0.011478908364357165 0.08205743919561527 0.0 0.0 0.08070082234700063 0.019572824388875868 5.152521285133451e-11 10.287980205468806 0.028836281299631117 EGYAWAEDKEHCEEYGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EGYAWAEDKEHCEEYGR 17 1 Q9Y3I0 Q9Y3I0 RTCB tRNA-splicing ligase RtcB homolog 0 93.10600000000001 0.00087079 6988600.0 38800.0 39249.0 44465.0 48979.0 55876.0 38664.0 41841.0 47182.0 44028.0 34008.0 False True 45368.073665068565 43145.38133239551 45525.21423445153 46234.8654220605 44927.498909222166 36636.391775918 37877.51757739263 45943.522493461285 44671.82620720735 40173.3811928201 1.1293068275063904 1.073979337843402 1.1332183869698258 1.1508830984414058 1.1183399946741783 0.9119568900629592 0.9428511231253347 1.1436309598374665 1.111975763075457 1.0 15.293952270477972 -6.583596685989165 24.999994862650134 1.0248898722378461 1.1211629237764194 0.3519884238224722 0.06716275448535262 94.08493308985165 38737.56602193237 0.024447730438446145 0.024447732508981853 2.608574917285428e-07 6.583596685989165 0.09627305153857324 EHAASLCR ddPTM_PC-9_AZD4547_30min_R2 1 EHAASLCR 8 0 H3BPG2;H3BQF2;A0A0B4J287;H3BM91;Q9H0A8-2;Q9H0A8 H3BPG2 COMMD4 COMM domain-containing protein 4 0 107.01 0.0032034999999999998 614250.0 2240.6 2453.3 4124.1 6725.5 5051.7 4136.5 1409.1 3433.8 3145.0 4216.7 False True 2953.064192624817 3246.281248103708 4069.411739360928 5175.039882939189 4350.358653689307 3877.844001089764 1534.5071702115943 2903.1851108741666 3311.238279355248 4069.0746164635884 0.7257336055418198 0.7977934921540059 1.0000828500160641 1.2717977355344712 1.069127274316287 0.9530039054579879 0.37711453213537444 0.7134755158157581 0.8137570802850078 1.0 11.990485020668446 -7.036856489598284 24.780322282749527 0.6969024391622214 0.9842705788469011 0.2574053986201664 0.19994992719047372 671.4494609370591 451444.44169916963 0.08041730229394184 0.06231201096153558 9.18636104960974e-08 7.036856489598284 0.28736813968467967 EHALLAYT(ph)LGVK ddPTM_PC-9_AZD4547_30min_R2 1 EHALLAYTLGVK 12 0 Q5VTE0;P68104;A0A087WV01;A0A2U3TZH3;Q05639;A0A2R8Y660;A0A2R8Y488 Q5VTE0 EEF1A1P5;EEF1A1;EEF1A2 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha;Elongation factor 1-alpha 2 1 EHALLAYT(1)LGVK 89.624 0.015498 4011400.0 94804.0 59657.0 100480.0 97013.0 85838.0 75237.0 88107.0 92918.0 88655.0 86841.0 True False 124949.69995429918 78939.9585937811 99147.56954753432 74648.15168590879 73920.87537173266 70532.41849631099 95948.35231412442 78559.65814322513 93341.12230723041 83800.72302234318 1.4910336742677595 0.9419961516648718 1.1831350132993401 0.8907817139716788 0.8821030738842631 0.8416683765067926 1.1449585260564208 0.9374579992857499 1.1138462645763036 1.0 16.35467507092335 EHALLAYT(ph)LGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EHALLAYTLGVK 12 0 Q5VTE0;P68104;A0A087WV01;A0A2U3TZH3;Q05639;A0A2R8Y660;A0A2R8Y488 Q5VTE0 EEF1A1P5;EEF1A1;EEF1A2 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha;Elongation factor 1-alpha 2 1 EHALLAYT(1)LGVK;EHALLAY(0.001)T(0.999)LGVK 99.48100000000001 0.0069884 3717800.0 61582.0 56183.0 56107.0 72123.0 71524.0 71121.0 65072.0 81954.0 62996.0 44759.0 True False 72006.61630005807 61760.47693948833 57444.80366698243 68082.18213592097 57509.385639330074 67391.28955863504 58907.90907951755 79802.79433744085 63917.197323276836 52873.45238795093 1.3618671194708538 1.1680810340571335 1.0864583467236053 1.287643969914775 1.0876797909348475 1.274577061171676 1.1141301810082254 1.5093168827316203 1.2088712659482514 1.0 15.690255910549805 EHALLAYTLGVK ddPTM_PC-9_AZD4547_30min_R2 2 EHALLAYTLGVK 12 0 Q5VTE0;P68104;A0A087WV01;A0A2U3TZH3;Q05639;A0A2R8Y660;A0A2R8Y488 Q5VTE0 EEF1A1P5;EEF1A1;EEF1A2 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha;Elongation factor 1-alpha 2 0 ; 142.97 6.969100000000001e-05 17730000.0 157795.0 105994.0 189905.0 208937.0 189645.0 162214.0 211435.0 244585.0 174364.0 195820.0 False True 207970.52766010602 140254.4876743588 187386.7356182774 160769.80269447115 163316.06526098278 152070.73293672758 230252.30539613165 206790.00825416655 183580.5250688387 188964.401402969 1.1005804591554058 0.7422270365901581 0.9916509894298704 0.8507941257762487 0.8642689525034357 0.8047586307668332 1.2184956726590828 1.0943331480366199 0.9715085153914831 1.0 17.527754948265702 -7.250726005800461 24.999601025260194 1.0789454343764298 0.8868991673939474 0.3814121938589834 0.11118074557316832 688.0688210967512 1605607.91636764 0.04084320452278748 0.03130340221146558 5.614020500525584e-08 7.250726005800461 -0.1920462669824824 EHALLAYTLGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EHALLAYTLGVK 12 0 Q5VTE0;P68104;A0A087WV01;A0A2U3TZH3;Q05639;A0A2R8Y660;A0A2R8Y488 Q5VTE0 EEF1A1P5;EEF1A1;EEF1A2 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha;Elongation factor 1-alpha 2 0 ; 136.38 5.3056e-05 20687000.0 245542.0 223608.0 218569.0 297000.0 326510.0 268510.0 312330.0 288500.0 263420.0 234162.0 False True 287107.4109244397 245806.3244662109 223780.51388754862 280360.05288699106 262532.70937164663 254428.86291515987 282743.84132661845 280927.18069101695 267272.0191583214 276613.7169746275 1.0379362746887015 0.8886266637628732 0.8090000609336194 1.0135435652047118 0.9490950493815443 0.9197984311764895 1.0221613173021107 1.0155938171236283 0.9662283638046663 1.0 18.077513174383625 -7.257825173117255 24.85712995409231 1.0022953601995788 0.9324666111098451 0.2109356021820874 0.060973636663846566 464.0150057732164 3191334.270092618 0.024654813708557342 0.018351049480655874 5.5229972487546556e-08 7.257825173117255 -0.06982874908973369 EHALLAYTLGVK ddPTM_PC-9_Lapatinib_30min_R1 2 EHALLAYTLGVK 12 0 Q5VTE0;P68104;A0A087WV01;A0A2U3TZH3;Q05639;A0A2R8Y660;A0A2R8Y488 Q5VTE0 EEF1A1P5;EEF1A1;EEF1A2 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha;Elongation factor 1-alpha 2 0 ; 101.89 0.0021652 18563400.0 127455.0 119428.0 139898.0 132404.0 141745.0 132186.0 131087.0 118953.0 133972.0 111861.0 False True 125637.46832761532 119151.47180363422 128396.12646189709 142141.43184679584 133407.83778139207 126532.7129206163 137874.043446383 124479.99063927634 118882.66257229689 131196.02480458686 0.9576316699743695 0.9081942229660335 0.9786586647967409 1.0834278863137192 1.0168588414176394 0.964455387341831 1.0509010745694687 0.9488091641853182 0.9061453100379343 1.0 17.00136448188067 -5.508753937552538 24.22840297694717 0.9982655318818012 0.9355412961494859 0.20493464754389878 0.04866506651140565 672.8660425720913 1154169.8174189548 0.013598975598486641 0.026609051465487296 3.0991747314357953e-06 5.508753937552538 -0.06272423573231534 EHAPLAS(ph)PVENK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EHAPLASPVENK 12 0 Q9ULJ3 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 EHAPLAS(1)PVENK 92.26899999999999 0.0033734999999999998 3835600.0 35590.0 49686.0 43045.0 39824.0 52055.0 32250.0 55347.0 48426.0 40122.0 36107.0 True False 41614.68406545849 54618.497716665486 44071.35604907154 37592.79039115 41855.19642994416 30558.753227119683 50104.131482420395 47154.86881158826 40708.708346633364 42652.91327714524 0.9756586565391052 1.280533813992297 1.0332554722044354 0.8813651284938933 0.9812974827295438 0.7164517234393463 1.1746942385121382 1.1055486059109427 0.954418003809516 1.0 15.380356663342754 -4.4479020395890725 17.048219859752372 1.0156318942191052 0.2174643435056372 0.00603942367466459 0.14716526417030784 22011317.69942182 77807941.60429381 0.03830380772480321 644952361.0103533 3.5653154439013775e-05 4.4479020395890725 -0.798167550713468 EHAPLAS(ph)PVENK ddPTM_PC-9_Lapatinib_30min_R1 1 EHAPLASPVENK 12 0 Q9ULJ3 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 EHAPLAS(1)PVENK 78.902 0.0090497 4064600.0 40403.0 47311.0 42793.0 36373.0 54695.0 58078.0 66245.0 53670.0 54254.0 51423.0 True False 39826.84581099721 47201.45428627921 39274.72472575699 39047.99175677103 51477.94763450737 55594.13932643051 69674.84196072561 56163.704131967745 48143.343200052266 60311.39703315958 0.6603535611867881 0.7826290984492957 0.6511990545363011 0.647439682673943 0.8535359843547394 0.9217849703575015 1.155251666984566 0.9312287046026905 0.7982461950530305 1.0 15.880143033242963 -6.521011381841991 2.68506021765767 0.9696310245958132 0.6905724433741216 0.6723234401353368 0.09054736739733904 0.17512824739375263 2.5487035782219056 0.03313156790813866 0.035451660393082784 3.01292706138429e-07 6.521011381841991 -0.2790585812216916 EHASIDAQSGAGVPNPS(ph)TSASPK ddPTM_PC-9_Lapatinib_30min_R1 1 EHASIDAQSGAGVPNPSTSASPK 23 0 Q8IXJ6-5;Q8IXJ6-2;Q8IXJ6-3;Q8IXJ6 Q8IXJ6-5 SIRT2 NAD-dependent protein deacetylase sirtuin-2 1 EHASIDAQSGAGVPNPS(0.567)T(0.154)S(0.104)AS(0.175)PK 117.08 3.2331e-05 0.0 8844.8 8412.9 19292.0 12255.0 14404.0 14498.0 6806.7 12894.0 22357.0 8332.5 True False 8718.671530062335 8393.420446937032 17705.886229273554 13156.273581481575 13556.78503935357 13877.954336488687 7159.117620561114 13493.10231186124 19838.919230352927 9772.761522641651 0.8921400066770085 0.858858617136114 1.8117587529637702 1.346218625206495 1.3872010493600042 1.4200647692401043 0.7325583054467035 1.3806847000819837 2.0300218300006483 1.0 13.254550571735603 -5.218921510819366 24.206808871542847 1.3782947488266764 0.87549853167365 0.2632890412478702 0.34294814147922137 466.39251468025134 265530.03251364117 0.08802933029248454 0.2328986503570108 6.040577896785765e-06 5.218921510819366 -0.5027962171530264 EHASIDAQSGAGVPNPST(ph)SASPK ddPTM_PC-9_AZD4547_30min_R2 1 EHASIDAQSGAGVPNPSTSASPK 23 0 Q8IXJ6-5;Q8IXJ6-2;Q8IXJ6-3;Q8IXJ6 Q8IXJ6-5 SIRT2 NAD-dependent protein deacetylase sirtuin-2 1 EHASIDAQSGAGVPNPS(0.166)T(0.356)S(0.215)AS(0.263)PK 137.85 6.291800000000001e-08 6776200.0 7001.5 7373.2 32086.0 90446.0 47053.0 51915.0 19381.0 51325.0 28724.0 48778.0 True False 9227.831359753041 9756.442709215456 31660.518675380034 69595.07207677029 40520.50314390067 48668.7468431222 21105.871454028038 43393.90058116856 30242.291998791763 47070.2970668677 0.1960436184765109 0.20727387157458405 0.6726220280786277 1.4785347961136523 0.860850805473727 1.033958778165002 0.44839044512604626 0.9218956175169983 0.6424920572697852 1.0 15.522529337644482 -5.364555528091936 3.9745472355544473 0.9026682524118892 0.1993395859201187 0.5465015432448794 0.25425801407885257 0.16991614228801122 4.695815989730254 0.0697970795958574 0.15879244320263194 4.3196093435835835e-06 5.364555528091936 -0.7033286664917705 EHASIDAQSGAGVPNPSTS(ph)ASPK ddPTM_PC-9_AZD4547_30min_R2 1 EHASIDAQSGAGVPNPSTSASPK 23 0 Q8IXJ6-5;Q8IXJ6-2;Q8IXJ6-3;Q8IXJ6 Q8IXJ6-5 SIRT2 NAD-dependent protein deacetylase sirtuin-2 1 EHASIDAQSGAGVPNPS(0.049)T(0.122)S(0.648)AS(0.181)PK 182.23 8.127800000000001e-43 0.0 4316.2 4242.9 12569.0 35043.0 19447.0 19199.0 7492.9 20794.0 9173.7 18150.0 True False 5688.6618174628375 5614.334450568309 12402.326847561295 26964.37775895295 16747.11972965457 17998.483494964916 8159.753584329328 17580.765098583917 9658.60305352027 17514.57402443005 0.3247958990911259 0.32055215517872165 0.7081146724015107 1.5395394556180426 0.9561819605943596 1.0276289603081348 0.4658836448404493 1.003779199771661 0.5514609170652995 1.0 14.096268280032241 -5.390310745077943 4.206255831908608 0.932041618153491 0.32710344655429585 0.43206076224583234 0.2759874357059213 0.21300946739942445 6.175484821830045 0.07606475127979975 0.1683598799510193 4.0708889455358266e-06 5.390310745077943 -0.604938171599195 EHEEAVSVDR ddPTM_PC-9_Lapatinib_30min_R1 1 EHEEAVSVDR 10 0 Q13126-4;Q13126;Q13126-3;Q13126-2;B4DUC8 Q13126-4 MTAP S-methyl-5-thioadenosine phosphorylase 0 81.017 0.014152000000000001 2023000.0 8872.6 10257.0 11801.0 8270.1 11318.0 8725.9 7842.4 7292.6 14729.0 8487.8 False True 8746.075096964434 10233.250546688203 10830.767333177342 8878.31074224486 10652.297492044137 8352.713598066393 8248.441098842097 7631.440818945188 13070.064916753965 9954.904920717408 0.8785694254861995 1.0279606513761395 1.087983001287853 0.8918528919114013 1.070055171483895 0.839055085366345 0.8285806006721425 0.7666010755223991 1.3129271470542643 1.0 13.281191821495405 -3.2477682910758383 15.275767966789614 0.9617453033923484 0.41384911272863467 0.0 0.15476231405086113 0.0 0.0 0.03447213199152867 0.0 0.0005652384657823175 3.2477682910758383 -0.5478961906637138 EHEVFQR ddPTM_PC-9_AZD4547_30min_R2 4 EHEVFQR 7 0 O60884 O60884 DNAJA2 DnaJ homolog subfamily A member 2 0 ;;; 138.24 0.0026379000000000003 20292000.0 55500.2 51909.3 72314.0 81786.0 70133.0 68868.0 61945.0 80379.0 61201.0 70956.0 False True 73148.10912412572 68687.96608331223 71355.06911087176 62931.50128110396 60396.24353369993 64561.67307314155 67457.98499663414 67958.2724756699 64435.95991568215 68471.85203732543 1.0682945903705243 1.0031562465386359 1.0421080632078512 0.919085717833347 0.8820594410207669 0.9428936293113211 0.9851929367977573 0.9924994060132102 0.9410576462946667 1.0 16.06322341474756 -5.7518505470172006 24.999129204594848 0.9496254888012327 1.0343833213328153 0.535084118087449 0.036663556169921445 171.89161750372114 448135.80276845297 0.010802544995471296 0.018408673066728724 1.7707182075691934e-06 5.7518505470172006 0.08475783253158264 EHEVFQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EHEVFQR 7 0 O60884 O60884 DNAJA2 DnaJ homolog subfamily A member 2 0 ;;; 124.59 0.0038868 14481200.0 36203.3 37496.2 42283.3 40401.6 45757.0 37118.200000000004 42501.4 39101.0 32582.5 29744.000000000004 False True 42331.803642231345 41218.57493224717 43291.494232308236 38138.02933575448 36791.24431937286 35171.65624914339 38475.3597085107 38074.64018093402 33058.957422465995 35136.35174662556 1.204786539806223 1.1731034351398117 1.2320998646783494 1.0854294040193628 1.0470991577236313 1.0010047856639306 1.0950300129610302 1.083625313620975 0.9408762088010725 1.0 15.10067678175828 -5.919176670967052 3.671567115871177 1.0357072582249365 1.200072274070105 0.7561645945322883 0.04425571320386953 0.11650804557986857 3.0982910838847126 0.012963071528530004 0.019889567427259117 1.2045458315243454e-06 5.919176670967052 0.1643650158451686 EHEVFQR ddPTM_PC-9_Lapatinib_30min_R1 4 EHEVFQR 7 0 O60884 O60884 DNAJA2 DnaJ homolog subfamily A member 2 0 ;;; 124.59 0.0038868 20605900.0 59593.0 68258.0 70250.0 66476.0 76585.0 69174.0 59169.0 67592.0 72549.0 61998.0 False True 58743.19289198225 68099.95279475904 64474.316172842 71364.86679743526 72080.4208719032 66215.58927246984 62232.48130385949 70732.57107672744 64377.76764516145 72714.27169285776 0.8078633193234913 0.9365417710901456 0.8866803541013103 0.9814423652467794 0.991282992922876 0.9106271400497814 0.8558496132193562 0.9727467446211806 0.8853525744862113 1.0 16.14995093048661 -1.5229127938113043 0.012040876582305361 1.7202520236029837 7.237245745138792e-07 0.19088551529333742 0.05495109796819745 17799.987768899777 16.622259231830853 992.741799812536 1416.8805558586116 0.029997648102999874 1.5229127938113043 -1.7202512998784092 EHFAQFGHVR ddPTM_PC-9_AZD4547_30min_R2 2 EHFAQFGHVR 10 0 H0YJW7;A0A087WUN7;H0YJ40;G3V4X6;G3V2S9;Q9GZT3-2;Q9GZT3;H0YJ07;H0YJU7 H0YJW7 SLIRP SRA stem-loop-interacting RNA-binding protein, mitochondrial 0 ; 140.17 5.1535e-05 14645500.0 42331.0 42587.0 53417.0 74051.0 55144.0 55356.0 47303.0 63186.0 43008.0 51064.0 False True 55791.377460502146 56352.414915824644 52708.65567795223 56979.686026545256 47488.20745472677 51894.58056915873 51512.875361946644 53422.05556983374 45281.3150774278 49276.26490267194 1.1322160389124163 1.1436015904843675 1.069656066304128 1.1563312710305609 0.9637136164545578 1.0531354328835265 1.0453892043906403 1.084133622451912 0.9189275032688705 1.0 15.58860528471755 -5.545290990579698 0.36033624667510666 0.9901909263100912 1.210126016920969 0.46708443763953833 0.05418069545948344 3.4537249295576364 0.5393214507055123 0.05346621549727464 0.3151035263294066 2.849108637932701e-06 5.545290990579698 0.2199350906108779 EHFAQFGHVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EHFAQFGHVR 10 0 H0YJW7;A0A087WUN7;H0YJ40;G3V4X6;G3V2S9;Q9GZT3-2;Q9GZT3;H0YJ07;H0YJU7 H0YJW7 SLIRP SRA stem-loop-interacting RNA-binding protein, mitochondrial 0 78.098 0.008775299999999998 3436700.0 8734.9 10251.0 10544.0 11807.0 13344.0 9753.1 10467.0 10017.0 9874.0 8138.2 False True 10213.546047861015 11268.651533501152 10795.408948342674 11145.492068810472 10729.338990705495 9241.630266648712 9475.48998548239 9754.064363888812 10018.388570227247 9613.591238044248 1.0624069398168856 1.1721583802010707 1.1229319700656266 1.1593474064826026 1.1160594126621335 0.9613088426389963 0.985634790460474 1.0146119303771377 1.042106775934167 1.0 13.230859747240926 -6.690210956269628 6.508029644892494 1.0009288708141282 1.1319769914323343 0.7807533454222677 0.03333213843296947 0.0939698275379348 6.750554605177999 0.010980995616912724 0.010916551099392857 2.0407464219910706e-07 6.690210956269628 0.13104812061820614 EHFGTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EHFGTVK 7 0 H7C1D4;E9PGT1;Q15631-2;Q15631 H7C1D4 TSN Translin 0 79.116 0.022945 1199200.0 14676.0 20133.0 18746.0 19654.0 19328.0 19548.0 21610.0 17731.0 16565.0 15362.0 False True 17160.35693578728 22131.671185638344 19192.9757346009 18552.85009912772 15540.817147208923 18522.868467712735 19562.944357148615 17265.58003754741 16807.231787098874 18147.008994474912 0.9456300452053542 1.2195768014650026 1.0576385199590987 1.0223640768997455 0.8563844957557757 1.0207119241166551 1.0780258258043958 0.9514284168153625 0.926170907404964 1.0 14.147444161135283 -5.811661081225151 3.398637712906549 0.9753315374650322 1.0916835825760125 0.22352917479679757 0.08328740826061923 0.318125435991951 7.483361384477963 0.023911174015201982 0.03937627991552 1.5429040490913841e-06 5.811661081225151 0.1163520451109803 EHFQDDVFNEK ddPTM_PC-9_AZD4547_30min_R2 2 EHFQDDVFNEK 11 0 P43490;A0A0C4DFS8 P43490 NAMPT Nicotinamide phosphoribosyltransferase 0 ; 110.64 0.0013880000000000001 3048400.0 59205.0 81736.0 91245.0 108711.0 83421.0 89702.0 76493.0 105301.0 78225.0 69136.0 False True 78030.95845949848 108155.56356540356 90035.03168157606 83649.35851820713 71839.43410127598 84092.91975964072 83300.72881342364 89029.15002625673 82359.8138004973 66715.56968336077 1.1696064176599519 1.6211442708009756 1.3495355298454612 1.2538206435951298 1.0768016287986992 1.2604691852105097 1.2485950312464964 1.3344583647984811 1.2344916515198145 1.0 16.025735867851502 -14.522878744100199 0.0758186793992939 0.11103581586310683 1.580174284762198 0.30690923044317475 0.1326497768400065 357.1447346663703 1.9239811493481993 54.97428343087497 5.7558681191073635 3.00000000815211e-15 14.522878744100199 1.4691384688990912 EHFQDDVFNEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EHFQDDVFNEK 11 0 P43490;A0A0C4DFS8 P43490 NAMPT Nicotinamide phosphoribosyltransferase 0 ;;; 148.78 0.0001155 13254200.0 123714.0 161056.0 145914.0 151104.0 163134.0 123503.0 145511.0 105572.0 119570.0 105234.0 False True 144656.33673712108 177044.5752979769 149393.14314192685 142638.13276577776 131169.0637672178 117026.28526539421 131727.14467158943 102800.84686277997 121318.48504578421 124312.09116811461 1.1636546001104087 1.4241943292430743 1.201758748792132 1.147419622865806 1.0551593375565542 0.9413910116525401 1.0596486909181424 0.826957747205429 0.9759186246953084 1.0 16.923607100834566 -6.126977417058276 1.1890181624950993 0.9496747634994664 1.297908766800689 0.7176058546797993 0.08340628115887919 0.23320862288006367 0.6744205769300612 0.03174681475292568 0.053540602394456044 7.464875741164505e-07 6.126977417058276 0.34823400330122256 EHFQDDVFNEK ddPTM_PC-9_Lapatinib_30min_R1 4 EHFQDDVFNEK 11 0 P43490;A0A0C4DFS8 P43490 NAMPT Nicotinamide phosphoribosyltransferase 0 ;;; 122.34 0.00056943 22908700.0 159068.0 199701.0 219966.0 196784.0 218721.0 210111.0 211039.0 223040.0 206382.0 209539.0 False True 156799.6611505015 199238.60460409292 201881.24457331438 211256.15181218015 205856.26080203106 201125.04232266356 221965.56679824268 233403.25264755142 183137.08586119334 245757.5369568327 0.6380258489408744 0.8107120826129096 0.8214651199437063 0.8596120974686009 0.8376396644884576 0.8183880942702937 0.9031892553400344 0.9497297846395193 0.7451941784937459 1.0 17.906876136632405 -4.0147233824513915 0.9243585955545278 0.8712217920197902 3.9162572054684964e-27 0.5203629804802732 0.06694860333730991 6.011114251227273 1.4516940126869526 0.021229921519829532 7.389644212184739 9.666663870338757e-05 4.0147233824513915 -0.8712217920197902 EHGAFDAVK ddPTM_PC-9_Lapatinib_30min_R1 4 EHGAFDAVK 9 0 V9GZ78;V9GYY3;A0A384N5Y3;F5H2F4;P11586;A0A494C1T2 V9GZ78 MTHFD1 C-1-tetrahydrofolate synthase, cytoplasmic;Methylenetetrahydrofolate dehydrogenase;Methenyltetrahydrofolate cyclohydrolase;Formyltetrahydrofolate synthetase;C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed 0 ;;; 106.2 0.0021698 12241500.0 173555.0 151651.0 160774.0 142909.0 154424.0 136470.0 138804.0 144542.0 153381.0 139587.0 False True 171080.07387391073 151299.86142690975 147555.78232558697 153419.00459044898 145341.08392926527 130633.49622710788 145990.59194681182 151257.94899651344 136105.61660646606 163714.4269620139 1.044990823646873 0.9241693858905625 0.9012998125072009 0.9371135301719393 0.8877719980230468 0.7979351523944699 0.8917393210598692 0.9239133765016891 0.8313599426276963 1.0 17.320821936074445 -1.5228930680727184 0.9602997017468847 0.8870848603789614 119.92085624558298 0.41303128877512174 0.052487881541506465 1232.5609043872948 2.0248367349622196 0.01645046501088764 322416.9535319115 0.029999010632867695 1.5228930680727184 119.03377138520402 EHGAVAVER ddPTM_PC-9_AZD4547_30min_R2 1 EHGAVAVER 9 0 Q9UNZ2-4;Q9UNZ2;Q9UNZ2-5;F2Z2K0;Q9UNZ2-6 Q9UNZ2-4 NSFL1C NSFL1 cofactor p47 0 80.706 0.015356999999999999 1636700.0 5353.6 4116.2 4869.6 12031.0 10312.0 10308.0 8384.6 6212.2 8377.6 7605.6 False True 7055.9334382023635 5446.681153321846 4805.025922259886 9257.438827097081 8880.356798076717 9663.439130480663 9130.813156877535 5252.247232154613 8820.422832790631 7339.33025896447 0.9613865556171208 0.7421223682731967 0.6546954221593841 1.2613465398685089 1.2099682784038766 1.316664980251769 1.244093511901157 0.7156303159596022 1.2018021429158487 1.0 12.841432702477793 -5.7618852312692495 24.999953302902078 1.1389531100058226 0.7816735189642338 0.44872906052782235 0.1775117388016621 11.157295080140257 625685.3860655173 0.05183427497146969 0.0825448539785826 1.7302735491418692e-06 5.7618852312692495 -0.3572795910415888 EHGAVAVER ddPTM_PC-9_Lapatinib_30min_R1 1 EHGAVAVER 9 0 Q9UNZ2-4;Q9UNZ2;Q9UNZ2-5;F2Z2K0;Q9UNZ2-6 Q9UNZ2-4 NSFL1C NSFL1 cofactor p47 0 74.84100000000001 0.022528 2067500.0 9552.5 8455.7 11835.0 8033.2 11347.0 14385.0 10798.0 7343.6 13600.0 13472.0 False True 9416.279598286048 8436.12134616666 10861.971984421143 8623.988325969622 10679.591769060336 13769.78708307281 11357.067604980219 7684.810465129839 12068.224785651028 15800.617249688366 0.595943781783067 0.5339108727751154 0.6874397254724572 0.5458007234584277 0.6758971247956131 0.8714714663026465 0.7187736672251973 0.4863614087785973 0.763781857059353 1.0 13.947693297804388 -6.518174702116712 24.38011197877043 0.737426046584269 0.5957708420096539 0.28242467827717976 0.12873077742478078 240.4818876832885 1246380.4458908061 0.042088052135547185 0.04319087451758396 3.0326709968742997e-07 6.518174702116712 -0.1416552045746151 EHHWVPR ddPTM_PC-9_AZD4547_30min_R2 1 EHHWVPR 7 0 H0Y3P2;D3DQV9;P78344-2;P78344;H0YCH5 H0Y3P2 EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 0 84.244 0.016858 2840500.0 10929.0 8077.3 11317.0 15047.0 10749.0 9341.0 8439.0 12749.0 12235.0 11835.0 False True 14404.194662678136 10688.129264789504 11166.92918560356 11578.146623832583 9256.686891245787 8756.90579334691 9190.054651490771 10778.934992875167 12881.71712175245 11420.660252293645 1.2612400985998422 0.935859138497967 0.9777831525424174 1.013789603057959 0.8105211683699932 0.7667600296216005 0.8046868086847347 0.9438101436132296 1.1279310335114274 1.0 13.479358437883743 -2.3103909017434594 1.246864874730834 0.9111207884830115 199.95700651835972 0.45077014833427076 0.10694186116276773 790.7743106277211 2.8891920377135043 0.033748397233172724 448332.048454422 0.004893381753694978 2.3103909017434594 199.04588572987672 EHIEELLR ddPTM_PC-9_AZD4547_30min_R2 1 EHIEELLR 8 0 H0YMC2;B4DIH5;P61201;P61201-2 H0YMC2 COPS2 COP9 signalosome complex subunit 2 0 98.58200000000001 0.0056766 0.0 6572.1 6774.8 6536.8 6928.4 7198.5 6887.1 7596.7 8867.6 7809.2 7639.7 False True 8661.891091827883 8964.621611565246 6450.117760930757 5331.164422712938 6199.112530154694 6456.448548266729 8272.791583242079 7497.316177176242 8221.978369202225 7372.236428343705 1.1749339804846601 1.215997573965394 0.8749200902092994 0.7231407286690442 0.8408727243637013 0.8757788238374874 1.1221549476405899 1.0169663235909865 1.1152624375408737 1.0 12.847886623743772 -9.875021206833756 15.42687108406109 1.0000032910993257 0.9867621795053709 0.0 0.1546994704911148 0.0 0.0 0.167606466096641 0.04065053901487979 1.3334563171824687e-10 9.875021206833756 -0.013241111593954802 EHIEELLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EHIEELLR 8 0 H0YMC2;B4DIH5;P61201;P61201-2 H0YMC2 COPS2 COP9 signalosome complex subunit 2 0 93.14299999999999 0.008435600000000001 0.0 8947.8 8791.3 9636.3 11219.0 10797.0 8852.8 9984.6 8107.2 9330.5 7443.1 False True 10462.485812894347 9664.042164322364 9866.065937871252 10590.435802488757 8681.405356913016 8388.54358353628 9038.786405755949 7894.394590288446 9466.94091092823 8792.475110452822 1.189936358245263 1.0991264738223017 1.122103368383961 1.2044885734050532 0.9873676351488601 0.9540594062715818 1.028013874615386 0.8978580537468108 1.0767094352844488 1.0 13.102053630568728 -6.274837175172664 24.50885609283 0.9855978131470651 1.1477281521121552 0.7019520635067732 0.05198651302921966 317.34248777270295 580519.6721518758 0.015247549962263523 0.017391106752985795 5.310835196919281e-07 6.274837175172664 0.1621303389650901 EHIEELLR ddPTM_PC-9_Lapatinib_30min_R1 1 EHIEELLR 8 0 H0YMC2;B4DIH5;P61201;P61201-2 H0YMC2 COPS2 COP9 signalosome complex subunit 2 0 132.76 0.0034220999999999995 1372900.0 12668.0 16705.0 19195.0 21286.0 18955.0 17840.0 17279.0 16977.0 21105.0 14069.0 False True 12487.351996973319 16666.320598852148 17616.86119484272 22851.443448014405 17840.104166963843 17077.02478707118 18173.622073203685 17765.813397585553 18727.93265449742 16500.807904235873 0.7567721574267723 1.0100305812646777 1.0676362816344496 1.3848681580099045 1.0811654962896795 1.034920525478476 1.101377713059637 1.0766632458659762 1.1349706489031868 1.0 14.010249042256927 -4.779618735414973 2.137722452448976 1.117842194324903 0.65839741064146 0.5387061471303467 0.09891309140952202 0.5402066270604177 2.8034821726189114 0.027248502993314275 0.4859120777706943 1.6610444887824228e-05 4.779618735414973 -0.4594447836834431 EHIYDLR ddPTM_PC-9_AZD4547_30min_R2 2 EHIYDLR 7 0 Q14677-2;Q14677;Q14677-3 Q14677-2 CLINT1 Clathrin interactor 1 0 ; 104.37 0.0086955 8191700.0 49671.0 47838.0 62879.0 80345.0 70987.0 56709.0 53381.0 62719.0 52992.0 63362.0 False True 65465.34477901781 63300.69797692305 62045.183375591245 61822.70156787594 61131.68037481294 53162.977265272406 58131.805587300514 53027.21968924134 55793.0489346878 61143.71566589179 1.0706798575464525 1.0352772527403746 1.0147434237497988 1.0111047536871056 0.999803163891043 0.8694757373884733 0.9507404801002072 0.8672554343769113 0.9124903242642026 1.0 15.899916606126197 -6.6086072161395135 5.060667929225379 0.9139682734079962 1.0290051151615875 0.6526495166104841 0.039146204367322676 0.12231813962635052 5.375853038373201 0.012652127946503187 0.01266326500141263 2.462593812099682e-07 6.6086072161395135 0.1150368417535913 EHIYDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EHIYDLR 7 0 Q14677-2;Q14677;Q14677-3 Q14677-2 CLINT1 Clathrin interactor 1 0 ;; 108.09 0.0017350000000000002 2126100.0 52790.0 50891.0 60228.0 63596.0 67348.0 56924.0 59931.0 58842.0 58128.0 49329.0 False True 61726.30434997347 55943.122153097924 61664.06393596197 60032.92230101384 54151.64286166325 53938.80523102517 54253.90181713438 57297.45984825252 58978.01203262808 58271.957211850844 1.0592797514173784 0.9600350636879019 1.0582116490746816 1.0302197690522203 0.9292916430589765 0.9256391549528316 0.931046500118254 0.9832767353247551 1.0121165454973537 1.0 15.830514147629755 -4.752601860439391 24.635672205297716 0.9795998947695022 1.0592799357441498 0.22942208818217313 0.04290931658421159 483.0523238171921 1346448.9533384354 0.011879397510676248 0.13655830769828153 1.7676575785851044e-05 4.752601860439391 0.07968004097464765 EHIYDLR ddPTM_PC-9_Lapatinib_30min_R1 3 EHIYDLR 7 0 Q14677-2;Q14677;Q14677-3 Q14677-2 CLINT1 Clathrin interactor 1 0 ;; 126.28 0.0038263000000000004 10133900.0 101540.0 81902.0 91166.0 82912.0 88552.0 77168.0 81267.0 78710.0 89513.0 75347.0 False True 100092.02097984473 81712.36095104381 83670.68339093667 89009.62506632412 83343.54545993039 73867.7045273941 85474.60761751508 82367.153944982 79431.10332632205 88370.62855643332 1.1326390070420982 0.9246551969341538 0.9468155286176868 1.0072308698074128 0.9431136433154071 0.8358852452907736 0.9672286936708971 0.9320648193916883 0.8988405381274106 1.0 16.43127932521758 -4.75914953522434 24.995076430196992 0.9374950659430722 1.1326392603578033 0.6061012381895841 0.04667500396186812 42.041084617169695 458800.4948243755 0.011751262829211157 0.07613578941040264 1.7412072419046066e-05 4.75914953522434 0.19514419441473108 EHMDEVCS(ph)SQLLTSVRR ddPTM_PC-9_AZD4547_30min_R2 1 EHMDEVCSSQLLTSVRR 17 1 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154;H0YBA1 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 EHMDEVCS(0.5)S(0.5)QLLTSVRR 71.545 0.012721 4850500.0 0.0 0.0 393.52 523.38 630.78 668.28 0.0 401.5 0.0 0.0 True False 0.0 0.0 388.3016676785996 402.7228271403929 543.2070850553556 626.4923459563074 0.0 339.45740055215157 0.0 0.0 0.0 EHMDEVCS(ph)SQLLTSVRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EHMDEVCSSQLLTSVRR 17 1 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154;H0YBA1 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 EHMDEVCS(0.5)S(0.5)QLLTSVRR 81.992 0.0045615000000000005 3602600.0 440.19 461.09 668.55 0.0 0.0 0.0 384.05 0.0 429.63 0.0 True False 514.705472851199 506.8639679623493 684.4907674899941 0.0 0.0 0.0 347.6700037187843 0.0 435.91252596989386 0.0 0.0 EHMQPTHPIR ddPTM_PC-9_AZD4547_30min_R2 3 EHMQPTHPIR 10 0 P61981 P61981 YWHAG 14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed 0 ;; 97.456 0.0021613 3421500.0 11901.240000000002 5935.200000000001 18517.399999999998 22847.8 19100.8 17929.6 15833.460000000001 26428.2 17283.0 17784.3 False True 15685.586758829862 7853.63733083811 18271.847176945765 17580.592704991155 16448.983623807577 16808.459277635448 17242.607266523653 22344.32894961986 18196.544096056194 17161.67707011963 0.9139891570469064 0.45762644867104263 1.0646889055358735 1.0244099474171382 0.9584718064906995 0.9794182240441307 1.0047157510348994 1.30198982642109 1.0603010429405166 1.0 14.066902922044365 -5.28489672304047 24.994643261628326 1.0518211726536821 0.6858078086407166 0.5310706662880462 0.13658965817802626 499.61855204487097 532360.8250849874 0.03536977735318084 0.07369610130166478 5.189234263173397e-06 5.28489672304047 -0.3660133640129656 EHMQPTHPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EHMQPTHPIR 10 0 P61981 P61981 YWHAG 14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed 0 75.229 0.016822999999999998 785930.0 489.91 447.74 993.3 592.14 735.18 695.47 0.0 671.18 899.17 0.0 False True 572.8420868364369 492.18866818942575 1016.9840391112269 558.9643155437818 591.1267565337885 658.9983288950365 0.0 653.5622361739928 912.3186601874855 0.0 0.0 EHMQPTHPIR ddPTM_PC-9_Lapatinib_30min_R1 6 EHMQPTHPIR 10 0 P61981 P61981 YWHAG 14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed 0 ;;;;; 103.22 0.0012258 9118110.0 20426.66 24129.199999999997 33238.799999999996 24821.21 25079.98 27015.38 19977.7 21800.75 34326.079999999994 22750.5 False True 20135.37208260932 24073.330319893612 30506.03416947842 26646.644584529255 23604.824885537844 25859.995173326624 21012.047554363155 22813.6924325507 30459.91540075292 26682.893611864256 0.7546172606128575 0.9022008883320537 1.143280583179114 0.9986414881435917 0.8846426189340356 0.9691600749713389 0.7874725979876627 0.854993193931817 1.1415521811026244 1.0 14.703627506833662 -8.259891001969697 24.98601168775869 1.0707760922537242 0.9190141453857023 0.2514334287509268 0.10911524603101568 206.089620237221 3325797.8741625585 0.08882675780113578 0.029425483181023105 5.496788134183915e-09 8.259891001969697 -0.1517619468680219 EHPDAWTR ddPTM_PC-9_Lapatinib_30min_R1 1 EHPDAWTR 8 0 O14980;C9IYM2;H7BZC5;F8WF71;C9IZS4;C9JQ02;C9JV99;C9J673;C9JKM9 O14980 XPO1 Exportin-1 0 111.74 0.0031399 5233000.0 13279.0 15122.0 18189.0 14789.0 16172.0 17906.0 13911.0 14002.0 20303.0 14129.0 False True 13089.639024929644 15086.985938092912 16693.570631570434 15876.632394657758 15220.79475537531 17140.2021209247 14631.243512954234 14652.584036814103 18016.26233993182 16571.178824290906 0.789903914725859 0.9104352863525685 1.0073858238196138 0.9580870837857929 0.9185100780557547 1.0343381302360752 0.8829331738009482 0.8842209834423834 1.0872046298554594 1.0 14.016388614786324 -4.833892688207907 3.098608376926268 0.9641187448347722 0.773293593612 0.43932669363864885 0.06207949193520751 0.30197859707573993 4.597830008571733 0.015491685165826578 0.13354206758389456 1.4659100145586485e-05 4.833892688207907 -0.19082515122277222 EHQHEEIQNVR ddPTM_PC-9_AZD4547_30min_R2 2 EHQHEEIQNVR 11 0 F5H6I7;Q6DD88 F5H6I7 ATL3 Atlastin-3 0 ; 79.23 0.007365399999999999 7416000.0 21870.3 28515.9 34105.0 36642.0 36862.0 22571.0 31561.0 37608.0 27997.0 25553.9 False True 28824.600469500387 37733.10701618252 33652.74541618889 28194.753013256697 31744.347584435993 21159.6318019091 34369.86785824153 31796.547745866297 29476.864262991676 24659.265739001825 1.1689156025400442 1.5301796661569984 1.3647099541558008 1.1433735826392852 1.287319254369695 0.8580803672691033 1.393791211061128 1.289436112267363 1.1953666656169002 1.0 14.589842221850143 -5.752848047397793 23.914322830666794 1.180447021322974 1.372159674260578 0.20823021205896475 0.1652962309050083 169.7505763057045 472498.0664784435 0.04427826186928199 0.07505220443579898 1.766655836814561e-06 5.752848047397793 0.19171265293760387 EHQHEEIQNVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EHQHEEIQNVR 11 0 F5H6I7;Q6DD88 F5H6I7 ATL3 Atlastin-3 0 91.469 0.0034388000000000005 1790700.0 13109.0 12854.0 13272.0 7987.6 18948.0 10747.0 15453.0 10951.0 10117.0 8416.5 False True 15328.094785448033 14130.060170873447 13588.454814340295 7540.080668148597 15235.275419356105 10183.408400987762 13989.17996996842 10663.547853543607 10264.941985516409 9942.344825022657 1.541698166298824 1.4211999703843752 1.366725360414094 0.7583805229901001 1.5323624041898372 1.0242461491939407 1.4070302545492874 1.0725385249871684 1.032446788576659 1.0 13.279370425030034 -5.53838050381644 24.99919506952534 1.140088325331462 1.4595776123362034 0.3457815174219804 0.20694159714800164 256.6227048924755 413845.78721939446 0.05353156157014633 0.09275530881314117 2.89480621380444e-06 5.53838050381644 0.31948928700474144 EHQTSAYS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EHQTSAYSPPR 11 0 H3BRF9;Q96K21-3;Q96K21-2;Q96K21;Q96K21-4 H3BRF9 ZFYVE19 Abscission/NoCut checkpoint regulator 1 EHQT(0.014)S(0.009)AYS(0.977)PPR 69.045 0.02023 8487000.0 9766.1 10435.0 14934.0 12317.0 18721.0 14966.0 12499.0 10978.0 9586.5 7728.4 True False 11419.30784073264 11470.91783748751 15290.083197510385 11626.918422252786 15052.754439822971 14181.156613862742 11315.004235076374 10689.839132152478 9726.684426623808 9129.497742019257 1.2508144657481368 1.2564675693704022 1.6748000415331208 1.2735551013654285 1.6488042239762482 1.5533337117323347 1.239389564991965 1.1709120736129461 1.0654128739038895 1.0 13.15631977739845 -7.645077359421622 2.1764029314622504 1.0636208865043753 1.4447218228892538 0.5464298682836395 0.1498265040250116 0.257728993942364 2.4346992410975394 0.0968308866762953 0.04544980367323021 2.2642409500122097e-08 7.645077359421622 0.3811009363848785 EHSDYVR ddPTM_PC-9_AZD4547_30min_R2 2 EHSDYVR 7 0 H0Y8P4;Q8TED0-3;Q8TED0 H0Y8P4 UTP15 U3 small nucleolar RNA-associated protein 15 homolog 0 ; 128.86 0.0037335000000000003 1903830.0 880.56 884.88 3502.0 4949.6 2120.8 3608.3 993.34 3494.5 2374.6 2602.87 False True 1160.5597632141876 1170.9001552284715 3455.5611918338486 3808.546190557703 1826.3635276727216 3382.6724305891944 1081.7453356454373 2954.505320621405 2500.1165081580193 2511.7443135519675 0.46205330572560915 0.466170122854842 1.3757615268359813 1.5162953370726941 0.7271295560693362 1.3467423464793713 0.430674941636752 1.176276305147999 0.995370625373287 1.0 11.294473895251038 -5.240773534623601 23.835350536188432 1.0679239273909997 0.4641113373004636 0.39111511531007104 0.3028851452097993 458.9210158509145 529301.1595332373 0.07719214561616916 0.2036200066989534 5.744159166356305e-06 5.240773534623601 -0.6038125900905361 EHSDYVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EHSDYVR 7 0 H0Y8P4;Q8TED0-3;Q8TED0 H0Y8P4 UTP15 U3 small nucleolar RNA-associated protein 15 homolog 0 ; 124.59 0.0038868 1692910.0 1624.7 2047.19 2982.4 1819.19 1638.6399999999999 1363.74 632.32 888.8499999999999 3183.7 1256.04 False True 1899.729620712291 2250.4214937926267 3053.511726814985 1717.2666821935563 1317.5602550756648 1292.2230736729362 572.4220719996393 865.5186293144218 3230.255589531344 1483.7501091928314 1.2803568531804557 1.5167119313756068 2.0579689988876315 1.157382682942318 0.8879933668833394 0.8709169190059322 0.3857941229140264 0.5833318049663153 2.1770886954061432 1.0 10.53503242070076 -5.965785902315345 8.946117808509662 0.9361644569000612 1.6096724497440105 0.25634891814883987 0.47917357642707686 0.3802850224488998 91.54763062845205 0.13710558277429633 0.20289551490585772 1.0819672060233413e-06 5.965785902315345 0.6735079928439492 EHSDYVR ddPTM_PC-9_Lapatinib_30min_R1 2 EHSDYVR 7 0 H0Y8P4;Q8TED0-3;Q8TED0 H0Y8P4 UTP15 U3 small nucleolar RNA-associated protein 15 homolog 0 ; 167.82 0.00022400000000000002 2421700.0 1762.21 991.0699999999999 1024.5 1859.8 2559.94 1394.06 1787.48 1506.74 1864.17 1642.52 False True 1737.0805622502635 988.7752383061589 940.2695646843641 1996.575896110927 2409.3693622356855 1334.439303512582 1880.0269681931882 1576.7486410248016 1654.2075440196384 1926.427393479672 0.9017108914302788 0.5132688839729129 0.4880898018097488 1.0364137796569364 1.2506930551292068 0.6927015822289609 0.9759137430024437 0.818483295223885 0.858691871605746 1.0 10.911712096903635 -5.765894648415027 24.99995421584425 0.9431868334288724 0.6222477482406459 0.4056707044534723 0.1734813853801288 109.41414150504784 613962.601859923 0.049750263534590174 0.07671865026451495 1.7143731314007723e-06 5.765894648415027 -0.32093908518822656 EHSLQVS(ph)PSLEK ddPTM_PC-9_AZD4547_30min_R2 3 EHSLQVSPSLEK 12 0 O95235-2;O95235 O95235-2 KIF20A Kinesin-like protein KIF20A 1 EHSLQVS(0.99)PS(0.01)LEK;EHSLQVS(0.994)PS(0.006)LEK;EHS(0.001)LQVS(0.968)PS(0.031)LEK 99.238 0.0019316 66888000.0 326320.0 261478.0 314814.0 384708.0 364160.0 309615.0 258215.0 346418.0 283883.0 289134.0 True False 430082.97212234687 345995.65001901984 310639.36066418636 296019.5142793503 313602.6698591553 290254.7251051396 281195.6347712628 292887.05799371126 298888.47582136875 279011.5066655399 1.5414524557150295 1.2400766339496383 1.113356808744665 1.060958086700698 1.1239775506286949 1.0402966120428763 1.007828093299181 1.0497311078456861 1.071240678900229 1.0 18.089965095656133 EHSLQVS(ph)PSLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EHSLQVSPSLEK 12 0 O95235-2;O95235 O95235-2 KIF20A Kinesin-like protein KIF20A 1 EHSLQVS(0.986)PS(0.014)LEK;EHSLQVS(0.982)PS(0.018)LEK;EHSLQVS(0.997)PS(0.003)LEK 95.06700000000001 0.0026704999999999997 52645000.0 259329.0 202554.0 225907.0 237711.0 246812.0 199178.0 247591.0 188434.0 186176.0 160295.0 True False 303228.27771877794 222662.22248724906 231293.47963706846 224392.8233394599 198450.96035476707 188732.75504717056 224137.38807638985 183487.80716232647 188898.47178961156 189355.21460547813 1.60137273404672 1.1758969667202783 1.2214793245539541 1.1850364079330091 1.048035359196418 0.9967127413966155 1.1836874339234884 0.9690137530388249 0.9975879047386247 1.0 17.53073562622093 -1.5228787452803607 0.5698966014465954 1.0338507680637588 27.609255639704127 0.8135083643890441 0.07758719847750421 62.365712357984805 0.5355571477543939 0.03704595201995178 2043.7562033368504 0.0299999999999984 1.5228787452803607 26.57540487164037 EHSLQVS(ph)PSLEK ddPTM_PC-9_Lapatinib_30min_R1 4 EHSLQVSPSLEK 12 0 O95235-2;O95235 O95235-2 KIF20A Kinesin-like protein KIF20A 1 EHSLQVS(0.986)PS(0.014)LEK;EHSLQVS(0.994)PS(0.006)LEK;EHSLQVS(0.961)PS(0.039)LEK;EHSLQVS(0.99)PS(0.01)LEK 90.49799999999999 0.0039192 68906000.0 384397.0 345919.0 383140.0 318192.0 321741.0 326024.0 292600.0 274946.0 318537.0 248353.0 True False 378915.4282902227 345118.0458087004 351639.7081631692 341592.9011373963 302816.82694714353 312080.7135190637 307749.39629720425 287720.99489972024 282660.00871668546 291280.4851404282 1.3008610175430915 1.1848306474850754 1.2072202777115035 1.1727284132087057 1.0396056117564951 1.0714096187000224 1.0565396996947334 0.9877798533637024 0.9704048954066157 1.0 18.15204952320577 -5.852974714032419 0.4868964031839811 0.9777570013276886 1.3321495208406737 0.9058012503482122 0.03219884538089956 0.5260601858386676 0.19708641737494204 0.02587320499241718 0.0966099642079836 1.4028953830911236e-06 5.852974714032419 0.3543925195129851 EHSLQVSPS(ph)LEK ddPTM_PC-9_AZD4547_30min_R2 1 EHSLQVSPSLEK 12 0 O95235-2;O95235 O95235-2 KIF20A Kinesin-like protein KIF20A 1 EHSLQVS(0.088)PS(0.912)LEK 131.32 0.00089372 0.0 33997.0 30369.0 33906.0 56092.0 43933.0 38600.0 29880.0 50366.0 40579.0 39912.0 True False 44807.338818470926 40185.185351836946 33456.384286213164 43160.85601276115 37833.661288780466 36186.335897997065 32539.262114770023 42583.09199554092 42723.92309632959 38514.69302826731 1.1633829921891163 1.0433728583100377 0.868665479474504 1.120633519812396 0.9823176121646091 0.9395462628103673 0.8448532120167307 1.1056323872109708 1.1092889424036945 1.0 15.23312130627019 -3.7239147350151494 13.945250246849865 1.0121694830340902 1.0164903362626179 0.0 0.10424616218903159 0.0 0.0 0.02435341589793991 0.0 0.00018883620546061955 3.7239147350151494 0.00432085322852771 EHSLQVSPS(ph)LEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EHSLQVSPSLEK 12 0 O95235-2;O95235 O95235-2 KIF20A Kinesin-like protein KIF20A 1 EHSLQVS(0.319)PS(0.681)LEK 113.54 0.00082171 6531800.0 38403.0 40423.0 42447.0 38968.0 39981.0 38457.0 37782.0 29874.0 28075.0 26872.0 True False 44903.86940617597 44435.92829369979 43459.09746114395 36784.74929596059 32147.010056009934 36440.247220320685 34203.01544200781 29089.83915411943 28485.543762318226 31743.680881365024 1.4145766388590608 1.39983540219451 1.369062952200241 1.1588054149559857 1.0127058098949604 1.1479527959126112 1.07747477584071 0.9163977946614401 0.8973610801084044 1.0 14.954181807073295 -5.850534495038785 0.6169687910704403 0.9536079675071907 1.5189879078115103 0.8709461181099107 0.06666552188770239 0.45347763890173964 0.29847450450553203 0.04540427812185067 0.155375374946903 1.410800175307094e-06 5.850534495038785 0.5653799403043196 EHSPYGPS(ph)PLGWPSSETR ddPTM_PC-9_AZD4547_30min_R2 1 EHSPYGPSPLGWPSSETR 18 0 Q96PC5;Q96PC5-11;Q96PC5-13;G3V599;Q96PC5-10;Q96PC5-9;Q96PC5-6;Q96PC5-12;Q96PC5-7;Q96PC5-14 Q96PC5 MIA2 Melanoma inhibitory activity protein 2 1 EHSPYGPS(1)PLGWPSSETR 134.83 3.4313e-05 3120700.0 12370.0 13359.0 16864.0 28568.0 24171.0 15885.0 17099.0 24420.0 22198.0 22558.0 True False 16303.402688016153 17677.035500516642 16640.37234125814 21982.08897120019 20815.27387183011 14891.708438851898 18620.777874847805 20646.4501157747 23371.34096188482 21768.25128612081 0.748953256452484 0.8120558361887029 0.7644331243028167 1.0098233745223129 0.9562216825887937 0.6841021928273441 0.8554099100610899 0.9484661787664425 1.0736434752931268 1.0 14.409937895381793 -7.918935342958693 3.003261373012186 1.0333948734525775 0.8349234155018137 0.449651631437062 0.09179029885644809 0.2615317791368661 4.623479164368344 0.0668001051917712 0.026712125763656513 1.2052153574769319e-08 7.918935342958693 -0.19847145795076382 EHSPYGPS(ph)PLGWPSSETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EHSPYGPSPLGWPSSETR 18 0 Q96PC5;Q96PC5-11;Q96PC5-13;G3V599;Q96PC5-10;Q96PC5-9;Q96PC5-6;Q96PC5-12;Q96PC5-7;Q96PC5-14 Q96PC5 MIA2 Melanoma inhibitory activity protein 2 1 EHSPYGPS(1)PLGWPSSETR;EHSPYGPS(1)PLGWPSSETR 105.46 0.00019376 5617700.0 20442.0 19142.0 25889.0 20797.2 39304.0 26267.0 25903.0 23715.0 19492.0 19386.0 True False 23902.426852096178 21042.291254929165 26506.291944579258 19632.000309432136 31602.663346124795 24889.51227958925 23449.280318520166 23092.50637811951 19777.033624758922 22900.52834050843 1.0437500173223297 0.918856147860473 1.1574532932365862 0.8572728112436323 1.3799971282856072 1.086853190000972 1.0239624156199514 1.0083831270072268 0.8636059976736693 1.0 14.483093262825317 -7.851306518544343 2.3744917880289536 0.934268776693345 1.0721077874602472 0.13508712266768708 0.13581952684308068 0.6144911576707064 6.771661617072071 0.09621443531598135 0.03819361954375863 1.408294494407411e-08 7.851306518544343 0.1378390107669022 EHTALLK ddPTM_PC-9_AZD4547_30min_R2 1 EHTALLK 7 0 C9K025;P18077;F8WBS5;F8WB72 C9K025 RPL35A 60S ribosomal protein L35a 0 89.369 0.013969999999999998 5042600.0 78661.0 85073.0 115940.0 133050.0 112800.0 100780.0 99049.0 114560.0 87904.0 106440.0 False True 103673.56174955837 112571.18355681212 114402.55984614973 102377.37810200869 97139.66706972955 94478.21066839763 107864.16911666162 96857.3843269103 92550.42598042722 102713.56799781472 1.0093463188014662 1.0959718930142424 1.1138018284846622 0.9967269183384498 0.9457335477996075 0.9198221083158916 1.0501452847880475 0.942985296051355 0.901053558789782 1.0 16.64826724217135 -5.933030513831973 5.016054691961071 0.9603997988679572 1.0745590664078648 0.5407645730690792 0.04652231422717676 0.1548271800435554 7.514978714950138 0.013536364250239503 0.02030653758724258 1.166727639086714e-06 5.933030513831973 0.11415926753990757 EHTALLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EHTALLK 7 0 C9K025;P18077;F8WBS5;F8WB72 C9K025 RPL35A 60S ribosomal protein L35a 0 124.34 0.0038959000000000003 2097700.0 38890.0 40072.0 36917.0 41829.0 52441.0 39670.0 50756.0 42461.0 38669.0 37786.0 False True 45473.30888748752 44050.083333377974 37797.24128850215 39485.456741447706 42165.56250086833 37589.63536495621 45948.024238382 41346.44374114833 39234.46097043931 44636.30268618856 1.018751692029321 0.9868667582767339 0.846782529328923 0.8846041084326942 0.9446472929738257 0.842131473774311 1.0293868773454509 0.9262963384720889 0.878980977574993 1.0 15.445929910363253 -10.345815529869178 4.583521596466621 1.0000002419919523 0.9275311630464484 0.10115520141907819 0.06365867759639686 30681812.44860774 50005522.16025477 128.81698977159385 0.01613636855300868 4.510082332952117e-11 10.345815529869178 -0.0724690789455038 EHTALLK ddPTM_PC-9_Lapatinib_30min_R1 2 EHTALLK 7 0 C9K025;P18077;F8WBS5;F8WB72 C9K025 RPL35A 60S ribosomal protein L35a 0 ; 116.88 0.0063784 5358600.0 72762.0 70763.0 73005.0 69737.0 71760.0 69883.0 66102.0 60714.0 68978.0 65081.0 False True 71724.40053708358 70599.15262116582 67002.81070744943 74865.69161581241 67539.21788558816 66894.26699522957 69524.43812043 63534.994087354 61208.97126945859 76330.16413501852 0.9396599804267691 0.9249181293031774 0.8778025236383592 0.9808139739275858 0.8848299836761746 0.8763804945696431 0.9108383154718488 0.8323707253526736 0.8018975455258758 1.0 16.21996567315217 -6.493578606564472 23.386046424651205 0.8760489138200326 0.927371794404807 0.1397150672176236 0.05426849260059373 568.092573609015 453425.7977425582 0.01644612646847912 0.018607028098731843 3.209381858965262e-07 6.493578606564472 0.05132288058477441 EHVEEISELFYDAK ddPTM_PC-9_Lapatinib_30min_R1 2 EHVEEISELFYDAK 14 0 Q9Y265;H7C4G5 Q9Y265 RUVBL1 RuvB-like 1 0 ; 170.0 0.0001436 3079800.0 37126.0 34247.0 35724.0 33346.0 37885.0 33799.0 37125.0 33944.0 34794.0 32764.0 False True 36596.57643192545 34167.7031756294 32786.91061862786 35798.37607899504 35656.67878477577 32353.495559317205 39047.15084597991 35521.1621586643 30875.133322936876 38427.2137447142 0.9523609147165774 0.8891538013299048 0.8532211269972134 0.9315891679479164 0.927901747486974 0.8419422697220025 1.0161327621977532 0.924375167938122 0.8034705177443123 1.0 15.229840753753718 EHVIEALR ddPTM_PC-9_AZD4547_30min_R2 4 EHVIEALR 8 0 F8W7C6;A0A087WV22;X1WI28;P27635;H7C123;H7C2C5 F8W7C6 RPL10 60S ribosomal protein L10 0 ;;; 118.33 0.0029439 19632200.0 115081.0 113319.0 138964.0 148201.0 132660.0 148360.0 132137.0 159222.0 133490.0 127805.0 False True 151674.36416649874 149947.15067617653 137121.24656253535 114035.54913262512 114242.44887828307 139083.02574680964 143896.93701671215 134617.8984575711 140546.0088747639 123330.58585081472 1.2298195384393107 1.2158147927518823 1.1118186589043073 0.9246331584816014 0.926310761358703 1.127725330965748 1.166757913489321 1.091520789663725 1.1395876205824045 1.0 16.912171105347333 -5.3509933253050015 3.822382513444516 1.0578944975907412 1.2245142303440257 0.40880452021185 0.07981531659497922 0.2505969588261081 6.713138622799123 0.024099679807039292 0.05606052073224957 4.456630977647296e-06 5.3509933253050015 0.16661973275328457 EHVIEALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EHVIEALR 8 0 F8W7C6;A0A087WV22;X1WI28;P27635;H7C123;H7C2C5 F8W7C6 RPL10 60S ribosomal protein L10 0 ;;; 121.05 0.0028445000000000002 14298600.0 118567.0 158100.0 151835.0 135162.0 164524.0 119941.0 140093.0 111246.0 113384.0 105363.0 False True 138638.0512950051 173795.12315350023 155455.32223744426 127589.3113411165 132286.70324541628 113651.0828159367 126822.37685451288 108325.91037488032 115042.02649854631 124464.47784695099 1.1138764544971842 1.3963431668207307 1.2489934873514792 1.0251062274812899 1.0628470510926336 0.913120633147145 1.0189443530262612 0.8703359564813695 0.9242960601177221 1.0 16.92537453041382 -5.88409548195931 2.0621348536339608 0.9564177689683846 1.2755147810650909 0.704467864625663 0.08318627720039579 0.16263765262293012 1.4080721223680177 0.0254840540179143 0.04437224880582473 1.305883751057618e-06 5.88409548195931 0.31909701209670627 EHVIEALR ddPTM_PC-9_Lapatinib_30min_R1 4 EHVIEALR 8 0 F8W7C6;A0A087WV22;X1WI28;P27635;H7C123;H7C2C5 F8W7C6 RPL10 60S ribosomal protein L10 0 ;;; 131.22 0.002938 25696200.0 136950.0 171047.0 169210.0 164960.0 178884.0 187891.0 190612.0 173275.0 174461.0 172479.0 False True 134997.06788644553 170650.95118059637 155298.20696948902 177091.70869042838 168362.3948194757 179855.3399253136 200480.95668832122 181325.98907148678 154811.36502422538 202291.7653361792 0.6673384240930431 0.8435882246467105 0.7676941605181319 0.8754271751800078 0.8322750782251672 0.8890887853315257 0.9910485301028014 0.8963587260714722 0.7652875279769872 1.0 17.626078067934316 -3.1575449218013456 0.3977014891279529 0.9129227330502336 2.393143705548987e-11 0.484661498725256 0.06971493431362437 18.62766786961297 0.8317769841492978 0.052510567953924475 10.591189934500225 0.0006957529848848373 3.1575449218013456 -0.9129227330263022 EHYPVSS(ph)PSSPSPPAQPGGVSR ddPTM_PC-9_Lapatinib_30min_R1 1 EHYPVSSPSSPSPPAQPGGVSR 22 0 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 EHYPVS(0.051)S(0.923)PS(0.019)S(0.006)PSPPAQPGGVSR 72.755 0.007655800000000001 0.0 11437.0 9653.4 10571.0 9272.8 10637.0 12283.0 9581.4 10515.0 12243.0 10262.0 True False 11273.906282711076 9631.048145403123 9701.89318524004 9954.752645153996 10011.352573146622 11757.684723071492 10077.478009849741 11003.565286894744 10864.064415494522 12035.77302674452 0.9366998079524671 0.8002018751934012 0.8060880812293154 0.8270970732859187 0.8317997149747288 0.9768948531137059 0.8372937897264031 0.9142383511589889 0.902647830874979 1.0 13.55504118492941 -6.729478183915245 24.98186814054257 0.9152972991603201 0.835502538587577 0.373875618097987 0.05445281176594508 220.6248038081136 172446.6649392018 0.01738686948706959 0.017385483386403347 1.8643258273095738e-07 6.729478183915245 -0.07979476057274315 EHYPVSSPS(ph)SPSPPAQPGGVSR ddPTM_PC-9_AZD4547_30min_R2 1 EHYPVSSPSSPSPPAQPGGVSR 22 0 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 EHYPVS(0.001)S(0.006)PS(0.485)S(0.485)PS(0.022)PPAQPGGVSR 60.45399999999999 0.0041975 5169700.0 11503.0 12322.0 18175.0 17399.0 20109.0 15620.0 13520.0 18800.0 16064.0 13113.0 True False 15160.71472273644 16304.845530156887 17933.98762466597 13387.929361870341 17317.21245660635 14643.278930743887 14723.25380828952 15894.891981022305 16913.11024469402 12653.917861286563 1.198104404416847 1.288521524234007 1.4172675863127948 1.0580066591730783 1.368525751979684 1.1572130537960563 1.163533221069333 1.2561241629085635 1.336590803741349 1.0 13.62729651576859 -11.380946440711721 2.728102642496278 0.8982639035543954 1.2482603961659415 0.3439437580252739 0.10329214268205625 10656605.416589437 6962032.343493651 7029330.591658376 0.02523377619965674 4.159619057576154e-12 11.380946440711721 0.3499964926115461 EHYPVSSPSS(ph)PSPPAQPGGVSR ddPTM_PC-9_AZD4547_30min_R2 2 EHYPVSSPSSPSPPAQPGGVSR 22 0 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 EHYPVS(0.06)S(0.196)PS(0.196)S(0.493)PS(0.056)PPAQPGGVSR;EHYPVS(0.02)S(0.063)PS(0.209)S(0.692)PS(0.016)PPAQPGGVSR 127.37 6.7295000000000005e-06 13895400.0 18660.7 20332.6 26092.2 36090.0 33126.0 30624.0 28477.9 41256.0 27072.0 29778.3 True False 24594.414433327664 26904.71532433598 25746.200379659374 27770.008084941706 28527.02669638179 28709.07643886689 31012.37793099764 34880.833168566816 28502.970651416614 28735.77078080909 0.8558814942160107 0.9362795774493036 0.8959634518261723 0.9663916202828163 0.9927357408987022 0.9990710413809388 1.0792255467081107 1.213847139672399 0.991898594571615 1.0 14.810560126712579 -6.4837925750348475 0.9914553635469264 1.0850827435977077 0.895257996116926 0.5550118053651165 0.06273268290624721 0.37691783369009185 0.7981544528619259 0.03155266357729443 0.038555062810108474 3.2825203332557787e-07 6.4837925750348475 -0.1898247474807817 EHYPVSSPSS(ph)PSPPAQPGGVSR ddPTM_PC-9_Lapatinib_30min_R1 3 EHYPVSSPSSPSPPAQPGGVSR 22 0 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 EHYPVS(0.017)S(0.018)PS(0.186)S(0.755)PS(0.024)PPAQPGGVSR;EHYPVSSPS(0.086)S(0.9)PS(0.014)PPAQPGGVSR;EHYPVSSPS(0.252)S(0.737)PS(0.011)PPAQPGGVSR 103.59 2.8206e-05 37657200.0 68720.0 58904.0 76410.0 61256.0 65969.0 69158.0 54492.3 63910.0 78019.0 64997.0 True False 67740.04019829528 58767.61140705099 70127.86475112966 65760.97058402578 62088.83312004415 66200.27355517201 57313.64466112834 66879.49191492569 69231.67864350793 76231.6448469415 0.888607878451321 0.7709083481675498 0.9199311505337834 0.8626466176357754 0.8144758419512867 0.868409355302374 0.7518353405098778 0.8773192818967354 0.9081750601408619 1.0 16.218102384966926 -8.525699070801748 1.986278642931008 0.998278102910598 0.8407957163882087 0.4955401595704615 0.04922306624490194 0.2755395622475986 2.4810138038285734 0.045563972889669166 0.012764074684499018 2.9805810036015563e-09 8.525699070801748 -0.15748238652238933 EHYVDLK ddPTM_PC-9_AZD4547_30min_R2 3 EHYVDLK 7 0 Q32Q12;P22392-2;J3KPD9;E7ERL0;E5RHP0;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Nucleoside diphosphate kinase A 0 ;; 96.492 0.007835600000000002 22595000.0 309605.0 316468.0 386410.0 303690.0 331593.0 400541.0 354472.0 428538.0 372348.0 343641.0 False True 408052.94981594494 418760.09213095985 381285.95092419157 233678.96246372798 285557.0356618161 375495.10795128555 386019.32129674655 362317.2989235821 392029.5551164919 331610.23318617966 1.2305197758684583 1.2628081109181293 1.1498015222893376 0.7046795878959832 0.8611225079459252 1.1323387229141 1.1640754194699998 1.0925998737806206 1.1821998113562147 1.0 18.33912900219677 -5.529896771138694 24.999695728028495 1.0198332890658126 1.2365742342504635 0.31010589683444667 0.13811239182367285 218.61537102405617 778751.3726702014 0.0421718761414763 0.07324235635979151 2.9519107925165807e-06 5.529896771138694 0.21674094518465092 EHYVDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EHYVDLK 7 0 Q32Q12;P22392-2;J3KPD9;E7ERL0;E5RHP0;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Nucleoside diphosphate kinase A 0 ;; 95.90899999999999 0.01089 25097500.0 180767.0 210416.0 207397.0 234573.0 224863.0 165097.0 224886.0 167781.0 154732.0 157834.0 False True 211367.2827890063 231304.7098891009 212342.13103750275 221430.63530592644 180802.70934255212 156439.02268334193 203583.17004635488 163376.926528664 156994.66277581544 186448.05478674345 1.1336523892982693 1.2405852673210447 1.1388809139380756 1.1876264172302335 0.9697216179023782 0.8390488324604651 1.091902891018146 0.8762597535036346 0.8420289659518498 1.0 17.508414219984097 -6.311756705028765 4.469793309952321 0.9301052661838487 1.178217940414796 0.7032318314572306 0.07617925736106028 0.11782349421051273 5.151445743936144 0.023719060279644943 0.027672271907058274 4.878016836739424e-07 6.311756705028765 0.2481126742309474 EHYVDLK ddPTM_PC-9_Lapatinib_30min_R1 4 EHYVDLK 7 0 Q32Q12;P22392-2;J3KPD9;E7ERL0;E5RHP0;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Nucleoside diphosphate kinase A 0 ;;; 98.39200000000001 0.01022 51256000.0 774515.0 985750.0 938690.0 918500.0 1007490.0 950280.0 1005320.0 922433.0 934100.0 928082.0 False True 763470.2740713439 983467.5564393016 861514.5316481857 986049.5540261767 948231.4190015515 909638.7396108747 1057370.550531461 965292.6046872272 828891.8214909277 1088499.7371084704 0.7013968382752702 0.9035073899529089 0.7914696736048312 0.9058794599671232 0.8711361029084557 0.8356811752911135 0.9714017509460294 0.8868101403969696 0.7614993308981641 1.0 20.05390962841451 -1.5228788450215933 0.027091992389772914 1.4841374860771879 3.656418194996246e-08 0.28915785230586366 0.07394132903243003 2390.754256131832 4.993393408709902 91.20507145243973 202.70952025228698 0.02999999311011893 1.5228788450215933 -1.484137449513006 EIAATCSGTEWGQSSGAAS(ph)PGLFQAGHR ddPTM_PC-9_AZD4547_30min_R2 2 EIAATCSGTEWGQSSGAASPGLFQAGHR 28 0 G3V3Z8;P49757-3;P49757 G3V3Z8 NUMB Protein numb homolog 1 EIAATCSGTEWGQS(0.002)S(0.005)GAAS(0.993)PGLFQAGHR;EIAATCSGTEWGQS(0.126)S(0.02)GAAS(0.854)PGLFQAGHR 123.08 4.2933999999999997e-13 30963000.0 43648.0 50604.0 69915.0 72823.0 66868.0 78287.0 69864.0 106333.0 66530.0 61486.0 True False 57527.156065200434 66960.75338484498 68987.88141835052 56034.78245413433 57584.532425697595 73391.70151415787 76081.76065549848 89901.67813925774 70046.63997631309 59333.39385488188 0.9695578211133656 1.1285508721887403 1.1627159165558887 0.9444054825379563 0.9705248374387337 1.2369375278558972 1.2822755570257771 1.515195277033032 1.1805601437132311 1.0 15.856556686493173 -6.872605789052961 5.357855301896551 1.283375681281515 1.043082294866015 0.35095135339356676 0.1367977502520481 0.21191405757727147 9.152184878976053 0.048447231611466 0.042763901166137964 1.3408932697138606e-07 6.872605789052961 -0.2402933864154999 EIAATCSGTEWGQSSGAAS(ph)PGLFQAGHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EIAATCSGTEWGQSSGAASPGLFQAGHR 28 0 G3V3Z8;P49757-3;P49757 G3V3Z8 NUMB Protein numb homolog 1 EIAATCSGTEWGQS(0.049)S(0.005)GAAS(0.946)PGLFQAGHR;EIAATCSGTEWGQS(0.001)S(0.001)GAAS(0.998)PGLFQAGHR 123.99 2.0125e-12 22492000.0 28037.0 39769.0 38310.0 50354.0 56729.0 43659.0 49998.0 34463.0 35143.0 37380.0 True False 32783.11034400844 43717.00349583521 39223.45569148409 47532.8286298706 45613.359682533875 41369.445182723044 45261.82748582678 33558.38276656685 35656.89989097594 44156.6981000828 0.7424266703480478 0.9900424030064249 0.888278729595738 1.0764579480588805 1.0329884625691326 0.9368781399586911 1.025027446192629 0.7599839709596384 0.8075082926299935 1.0 15.430344675471318 -10.407466614559754 6.315643866063225 1.0000000066668393 0.9261303908911316 0.04187266626407549 0.11173788486133851 1.0921806221320421e-08 1.8527251210636369e-09 0.11217870714591653 0.027207330420877737 3.913212079342591e-11 10.407466614559754 -0.07386961577570772 EIAATCSGTEWGQSSGAAS(ph)PGLFQAGHR ddPTM_PC-9_Lapatinib_30min_R1 2 EIAATCSGTEWGQSSGAASPGLFQAGHR 28 0 G3V3Z8;P49757-3;P49757 G3V3Z8 NUMB Protein numb homolog 1 EIAATCSGTEWGQS(0.039)S(0.035)GAAS(0.926)PGLFQAGHR;EIAATCSGTEWGQS(0.012)S(0.021)GAAS(0.967)PGLFQAGHR 75.119 1.6764e-05 28309000.0 28276.0 60152.0 69741.0 52096.0 66630.0 66230.0 68494.0 69323.0 62171.0 52712.0 True False 27872.779054816667 60012.72173972789 64007.16418804521 55927.313627161486 62710.95439962015 63397.4972896707 72040.28417628407 72543.99965605354 55168.6472903463 61823.19896567497 0.4508466000003007 0.9707152451468536 1.0353259821379155 0.9046331241806663 1.0143595842466526 1.0254645238411197 1.1652629657077718 1.173410643087733 0.8923615764525002 1.0 15.915860686164075 -4.756413727873625 3.872904048720633 1.0315796291055237 0.3780998006505146 0.7971477407485763 0.08652660941554759 0.12221192778174349 3.2585377748561597 0.023031554700272346 0.2358838910577125 1.7522104743430786e-05 4.756413727873625 -0.6534798284550092 down EIADGLCLEVEGK ddPTM_PC-9_Lapatinib_30min_R1 2 EIADGLCLEVEGK 13 0 Q5W0H4;A0A0B4J2C3;P13693;J3KPG2;E9PJF7 Q5W0H4 TPT1 Translationally-controlled tumor protein 0 ; 197.31 3.9467e-06 4429300.0 31952.0 27130.0 26890.0 25735.0 28989.0 26389.0 25221.0 29040.0 27026.0 27881.0 False True 31496.358620720814 27067.18215186222 24679.207998401707 27627.637749443347 27283.92401456683 25260.40398576353 26526.81997269923 30389.30441573213 23982.04728360328 32700.19370090275 0.9631856896263981 0.8277376702852675 0.7547113703403044 0.8448768836705892 0.834365822542929 0.7724848426529708 0.811212930887529 0.9293310215129759 0.7333915970944603 1.0 14.997011561159784 -11.434438732776563 3.3645415157589227 1.0861471094739672 0.8290768831658254 0.35811357430670665 0.06820788365675205 101008616.56548479 1182315.9936635008 67391816.8965583 0.015962808975694597 3.677572703386073e-12 11.434438732776563 -0.2570702263081418 EIAEAYLGK ddPTM_PC-9_AZD4547_30min_R2 2 EIAEAYLGK 9 0 P11142;E9PKE3;P11142-2;E9PN89;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65;E9PPY6 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 ; 152.47 0.00047087 5482000.0 102116.0 93617.0 96949.0 126325.0 118256.0 117329.0 103224.0 129126.0 95953.0 101780.0 False True 134586.7638552509 123876.86446978564 95663.39291464872 97202.72295179451 101838.19564714495 109992.3990822825 112410.73602861502 109172.54372029181 101024.879688068 98216.71317942072 1.3703040908057058 1.2612605376387354 0.9740031998412771 0.9896759910324644 1.0368723646973257 1.1198949295050236 1.144517388026057 1.1115475175885507 1.0285915341467124 1.0 16.583680923126323 -5.08270546451832 4.243122214246579 1.058468746415865 1.3508705861712742 0.786319540893033 0.05634529111836435 0.10183718786277092 3.268927527730179 0.016411590527449314 0.0519259318816722 8.265983527494205e-06 5.08270546451832 0.2924018397554091 EIAEAYLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EIAEAYLGK 9 0 P11142;E9PKE3;P11142-2;E9PN89;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65;E9PPY6 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 119.21 0.008068200000000001 5544000.0 36116.0 42037.0 31472.0 41797.0 40371.0 33308.0 33750.0 32083.0 34951.0 29306.0 False True 42229.72547648494 46210.15554714539 32222.411838224656 39455.24959770231 32460.592355648347 31561.269844617134 30552.955671159925 31240.855244748374 35462.09225420423 34618.945813831655 1.2198443506506913 1.3348227238243222 0.9307739181749004 1.139701070329483 0.9376539808638263 0.9116762253346011 0.8825501456763827 0.9024207557546828 1.0243550582073389 1.0 15.079274173222426 -5.343302322315023 1.0795977641212675 0.9391295965146712 1.3276473638659876 0.6191760430937028 0.08991386065902508 0.5019664540382037 0.8654741760451419 0.029926492052120265 0.18042535849375033 4.5362572747722364e-06 5.343302322315023 0.3885177673513164 EIAEAYLGK ddPTM_PC-9_Lapatinib_30min_R1 2 EIAEAYLGK 9 0 P11142;E9PKE3;P11142-2;E9PN89;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65;E9PPY6 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 ; 131.06 0.005739899999999999 46818000.0 202000.0 199746.0 210712.0 217761.0 210518.0 174727.0 219760.0 204090.0 189130.0 210589.0 False True 199119.44295773646 199283.50040935812 193388.07273184136 233775.87036940068 198135.74513431263 167254.33351853085 231138.09750606157 213572.76646717492 167828.1877728074 246989.02805779534 0.806187402426405 0.8068516321410272 0.7829824436030762 0.9465030580819858 0.8022046432279127 0.6771731312671646 0.9358233413185275 0.8647054816426865 0.6794965310505034 1.0 17.914087429128585 -11.79340948000531 2.418307018257401 1.8329580935822938 0.8153537278982893 0.3038253117183972 0.0854849897504312 6752746.673819595 1532696.13777518 30693452.647270493 0.02164737799347009 1.6091277334165205e-12 11.79340948000531 -1.0176043656840044 EIAENALGK ddPTM_PC-9_Lapatinib_30min_R1 1 EIAENALGK 9 0 P31942;P31942-2;P31942-3 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 0 93.111 0.029991000000000004 4101700.0 31367.0 29781.0 30577.0 25911.0 33812.0 29866.0 34462.0 27571.0 30190.0 29364.0 False True 30919.7008279967 29712.043924239177 28063.077090633313 27816.581376562142 31823.24463694969 28588.7008010464 36246.27373613897 28852.049312883984 26789.6842852062 34439.528274929464 0.8977968740212087 0.8627308622536594 0.8148507977985883 0.8076934490653709 0.9240325356057703 0.8301130193428863 1.0524613881696152 0.8377597126929021 0.777876051940815 1.0 15.07177776153854 -6.2695955321081165 24.617055772198533 0.899353111510808 0.8447712574098066 0.11202301038723161 0.07932836274704856 1274.5606938274161 3846897.7507861736 0.024727143445358216 0.028535533456176855 5.375321787287652e-07 6.2695955321081165 -0.05458185410100136 EIANS(ph)NER ddPTM_PC-9_AZD4547_30min_R2 1 EIANSNER 8 0 Q01664 Q01664 TFAP4 Transcription factor AP-4 1 EIANS(1)NER 76.92699999999999 0.024263999999999997 4442900.0 10982.0 16371.0 19763.0 24431.0 21939.0 18671.0 14900.0 17555.0 15547.0 16216.0 True False 14474.047560209641 21662.605597646376 19500.929707085197 18798.81040518732 18893.148544705673 17503.499418432726 16226.071134875274 14842.27812376842 16368.782680170438 15648.282775766249 0.9249607619965119 1.3843439505831414 1.2462025377816766 1.2013337613185353 1.207362418959133 1.1185572033207096 1.0369234354586063 0.9484924535460179 1.0460433847425095 1.0 13.933716725728663 -7.1049736021693874 1.9932303153663233 0.9972077163196212 1.20802173846564 0.38926536431472525 0.10872192028236098 0.32223192331028006 2.527342418102944 0.04931186984247847 0.035391867413017024 7.852833652355419e-08 7.1049736021693874 0.21081402214601874 EIANS(ph)NER ddPTM_PC-9_Lapatinib_30min_R1 1 EIANSNER 8 0 Q01664 Q01664 TFAP4 Transcription factor AP-4 1 EIANS(1)NER 72.652 0.032096 3864800.0 14227.0 14891.0 21548.0 14254.0 12781.0 15872.0 10435.0 11729.0 13876.0 8554.0 True False 14024.12037108773 14856.520804400312 19776.4066176854 15302.286709950084 12029.2467084128 15193.191559439116 10975.273241152869 12273.972158819637 12313.138759242174 10032.547502511461 1.397862344292619 1.4808323410062358 1.9712248172993694 1.5252643165775635 1.1990221531870646 1.5143901940793985 1.0939667356078218 1.2234153046120217 1.2273192582601586 1.0 13.292400366614327 -6.690076237513217 1.0619960795954138 1.1546578585475742 1.607623528954914 0.5018352392811005 0.1871675094651969 0.45381680260263485 1.0963611358769805 0.10346604999222124 0.10070628987609316 2.0413795625842213e-07 6.690076237513217 0.4529656704073397 EIAQDFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EIAQDFK 7 0 K7EMV3;A0A590UJJ6;B4DEB1;K7EK07;K7ES00;P84243;Q71DI3;Q16695;P68431 K7EMV3 H3F3B;H3F3A;HIST2H3A;HIST3H3;HIST1H3A Histone H3;Histone H3.3;Histone H3.2;Histone H3.1t;Histone H3.1 0 ; 119.27 0.030229000000000002 24654000.0 138351.0 217628.0 97151.0 200264.0 229700.0 211743.0 243020.0 213660.0 137215.0 136900.0 False True 161771.09174319296 239232.66958665423 99467.44828721914 189043.85734464772 184691.93391524724 200638.82432775229 219999.38628756392 208051.65139148277 139221.5097897239 161718.8863001966 1.0003228159937945 1.4793118791491664 0.615063896139991 1.168965862117849 1.1420554404041967 1.2406641482511147 1.3603815319330235 1.286501880833382 0.8608859050098135 1.0 17.303128647871425 -5.950185025594076 24.9998733020616 1.1759154099442302 1.0456203777158952 0.04352945951426368 0.23607306273058415 348.257384394135 174772.12889860466 0.06581213368507148 0.09761515748250332 1.1215405345427063e-06 5.950185025594076 -0.13029503222833494 EICELTGIDQSVLER ddPTM_PC-9_Lapatinib_30min_R1 1 EICELTGIDQSVLER 15 0 E9PDF6;O43795-2;O43795 E9PDF6 MYO1B Unconventional myosin-Ib 0 125.03 0.00012698 1400000.0 5991.9 4615.8 5890.5 5226.2 5619.3 6504.4 6051.5 6048.2 6810.2 5856.0 False True 5906.454407220114 4605.112398693909 5406.205827987555 5610.55218209212 5288.783821968869 6226.221974496965 6364.81705978309 6329.221452039644 6043.163561414751 6868.201797370483 0.8599710057269171 0.670497538446962 0.7871355541791653 0.8168880804055788 0.7700390841739245 0.9065286894861909 0.9267079284449511 0.9215252607258584 0.8798756559145362 1.0 12.745716713022036 -6.798541058576659 4.983682942527059 0.9239249397912785 0.7766560030444345 0.6569441297342957 0.05277801531195866 0.12051080539482197 7.0289379183182445 0.0181698793294784 0.01643840382741431 1.5902263353397785e-07 6.798541058576659 -0.14726893674684405 EIDCLS(ph)PEAQK ddPTM_PC-9_AZD4547_30min_R2 4 EIDCLSPEAQK 11 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3;C9JTC6 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 EIDCLS(1)PEAQK;EIDCLS(1)PEAQK;EIDCLS(1)PEAQK;EIDCLS(1)PEAQK 189.99 0.00055252 328145000.0 305690.0 277853.0 319866.0 391459.0 343606.0 299499.0 277158.0 332457.0 276757.0 307348.0 True False 402893.0612530042 367663.5485384424 315624.36784326856 301214.1755312608 295902.2379712905 280771.28018430644 301824.525073809 281083.4097518472 291385.8100093867 296587.84006944986 1.3584274431435275 1.2396447152126981 1.0641851256253831 1.015598533846592 0.997688367473195 0.9466715834289101 1.0176564386561935 0.9477239851978689 0.9824604068095136 1.0 18.17809992377647 -5.075157797042583 1.229596881215025 0.9790693239415175 1.4371924262645992 0.9724272006101171 0.021262766582855225 0.12497962104619914 0.23165453826906027 0.006332581623149879 0.06394991975164183 8.410894837261827e-06 5.075157797042583 0.45812310232308173 EIDCLS(ph)PEAQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 EIDCLSPEAQK 11 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3;C9JTC6 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 EIDCLS(1)PEAQK;EIDCLS(1)PEAQK;EIDCLS(1)PEAQK;EIDCLS(1)PEAQK;EIDCLS(1)PEAQK;EIDCLS(1)PEAQK 168.82 0.00022623 239338000.0 344486.0 327805.0 305865.0 338434.0 343196.0 287142.0 327153.0 278545.0 248721.0 213758.0 True False 402800.675891362 360347.3140122273 313157.98159947275 319472.64019783214 275949.2074530997 272083.76803539816 296162.6994573913 271233.4888928233 252358.07409109664 252510.6332926028 1.5951830251227757 1.4270579789591122 1.240177403684198 1.2651848994716808 1.0928221273491359 1.0775141010403095 1.1728721899572665 1.0741468006954182 0.9993958305853624 1.0 17.945984615867594 -1.5228787452831714 0.35110031834863015 1.0253053078640317 8.00107488647633 0.9355662116633001 0.046569815208916066 14.392903771428525 0.20243525693065653 0.04046888579272252 66.53507725604808 0.02999999999980425 1.5228787452831714 6.975769578612298 EIDCLS(ph)PEAQK ddPTM_PC-9_Lapatinib_30min_R1 5 EIDCLSPEAQK 11 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3;C9JTC6 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 EIDCLS(1)PEAQK;EIDCLS(1)PEAQK;EIDCLS(1)PEAQK;EIDCLS(1)PEAQK;EIDCLS(1)PEAQK 184.11 8.6926e-05 273351800.0 193317.0 262386.0 307105.0 264283.0 258825.0 237732.0 242699.0 215776.0 246585.0 184652.0 True False 190560.2641300041 261778.46133794807 281856.01235958136 283719.25344224373 243601.42236952833 227564.75654035943 255264.7666846729 225801.74068901566 218812.0006448353 216568.8521666764 0.8799061463526828 1.208753976940679 1.3014614499718475 1.3100649082439926 1.1248220597394452 1.0507732495401525 1.1786771926380957 1.042632578184574 1.010357668961705 1.0 17.72446623790006 -7.756504764743676 0.9524199822061329 0.9925245322857293 1.1741775223826028 0.19801886562193727 0.11825947922369791 0.9068249639049473 1.4964838967125251 0.11046439135314536 0.04591684067058609 1.7518432142322278e-08 7.756504764743676 0.1816529900968734 EIDGGLETLR ddPTM_PC-9_Lapatinib_30min_R1 2 EIDGGLETLR 10 0 P38117-2;P38117;M0QY67 P38117-2 ETFB Electron transfer flavoprotein subunit beta 0 ; 168.26 0.0013001 6249600.0 33931.0 32431.0 29733.0 27299.0 26009.0 26277.0 31308.0 22154.0 30902.0 25174.0 False True 33447.137717816666 32355.908012054697 27288.467512699088 29306.65952679439 24479.20175566143 25153.193964678794 32928.97504877947 23183.355717153237 27421.491347513806 29525.29235775349 1.1328300262887416 1.0958708763999037 0.9242403828571405 0.992595066348202 0.8290926118207622 0.8519202336729255 1.1152802366792538 0.7852032567957002 0.9287458025902591 1.0 14.849663724726256 -5.209936785961353 2.9006832021060833 0.9214834385604409 1.1317798230573919 0.405581682577945 0.09005089568562982 0.25808544472589545 4.213377112625555 0.023725678654301013 0.07857540829512329 6.1668475731252995e-06 5.209936785961353 0.21029638449695098 EIEDFDSLEALR ddPTM_PC-9_AZD4547_30min_R2 1 EIEDFDSLEALR 12 0 P46060;B0QYT5;B0QYT4 P46060 RANGAP1 Ran GTPase-activating protein 1 0 169.65 0.0047086 1599200.0 5711.7 5925.3 9608.5 5769.4 6032.1 7200.8 8547.9 10987.0 8891.1 6848.6 False True 7527.901789259645 7840.537349443158 9481.085011917627 4439.353966341439 5194.6470366251515 6750.532837676093 9308.646540523514 9289.211606143184 9361.065394459602 6608.832598551607 1.1390667984099736 1.1863725147405748 1.4346081354815226 0.671730430471846 0.7860158294467334 1.0214410392473159 1.408516012731749 1.405575261231312 1.416447648637851 1.0 12.69017973748088 -7.2552910364674945 24.458294787033342 1.3414326741567624 1.0362014011418192 0.2441440741171248 0.22766825345227285 517.3468284285307 2058027.2677907378 0.09504101670862251 0.07163346821669446 5.555318504819001e-08 7.2552910364674945 -0.3052312730149431 EIEDFDSLEALR ddPTM_PC-9_Lapatinib_30min_R1 2 EIEDFDSLEALR 12 0 P46060;B0QYT5;B0QYT4 P46060 RANGAP1 Ran GTPase-activating protein 1 0 ; 183.85 0.0023741 4720500.0 14342.3 18544.1 15888.400000000001 16745.5 21339.7 21646.6 20641.0 26206.0 20228.0 16470.1 False True 14137.776171944308 18501.162275796116 14582.117082997616 17977.01993135043 20084.54080146442 20720.8253786892 21709.689982811346 27423.626429706484 17949.70962971683 19316.93483997123 0.7318850681573954 0.9577690471633683 0.7548877295389446 0.9306352213888405 1.0397374618619533 1.072676672067713 1.1238682618470581 1.4196675951383666 0.9292214203971277 1.0 14.237578568857849 -6.3403589412030055 1.4036260249076666 1.1440913256066072 0.8238081823127804 0.4745007346983017 0.1340086369324602 0.33909144467889035 1.349927571999847 0.05100133192609937 0.06638284876650362 4.567105656528894e-07 6.3403589412030055 -0.3202831432938268 EIEIDIEPTDKVER ddPTM_PC-9_AZD4547_30min_R2 1 EIEIDIEPTDKVER 14 1 F8VSA6;E9PS38;S4R3E9;E9PL57;Q15843 F8VSA6 NEDD8;NEDD8-MDP1 NEDD8 0 136.3 6.9042e-05 4299400.0 19872.0 18784.0 28254.0 45576.0 42229.0 31874.0 26372.0 29803.0 24523.0 28870.0 False True 26190.882636722486 24855.560658859526 27879.333499164357 35069.15734218074 36366.23227559947 29880.91374126319 28719.05691066649 25197.631154808914 25819.23571530326 27859.27008734409 0.9401137414802723 0.892182766487874 1.0007201700459978 1.2587967032959688 1.3053548122971075 1.0725662821596138 1.0308617857046076 0.9044612825752277 0.9267735886243632 1.0 14.76586983938511 -7.5701148424618765 3.685226060027218 0.9374557535791631 1.0834244456983504 0.19258719558157555 0.12225906504197777 0.42518704477703534 12.068654261696839 0.07199937342062049 0.04021619640957346 2.6908231632524354e-08 7.5701148424618765 0.14596869211918728 EIEIDIEPTDKVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EIEIDIEPTDKVER 14 1 F8VSA6;E9PS38;S4R3E9;E9PL57;Q15843 F8VSA6 NEDD8;NEDD8-MDP1 NEDD8 0 ; 130.1 2.6604e-05 8296300.0 49756.0 47096.0 61640.0 74385.0 72431.0 69137.0 65808.0 58195.0 65465.0 45356.0 False True 58178.70807420492 51771.37963337914 63109.73137100178 70217.44960942396 58238.665500283976 65511.334011267456 59574.18983133901 56667.44291269931 66422.30177738766 53578.68376210154 1.0858554930637765 0.9662682245658155 1.177888797179485 1.3105482381986346 1.0869745467968857 1.2227126426275963 1.1119009585203425 1.0576490300566619 1.239715071619041 1.0 15.709371519273722 -5.272436768227134 24.45991995841817 1.1575697641722758 1.0260618575481704 0.2267941848363395 0.09156363676958647 636.8755451056072 1416513.5008283474 0.023221338704728027 0.04909001790321014 5.340270203993623e-06 5.272436768227134 -0.1315079066241054 EIEIDIEPTDKVER ddPTM_PC-9_Lapatinib_30min_R1 2 EIEIDIEPTDKVER 14 1 F8VSA6;E9PS38;S4R3E9;E9PL57;Q15843 F8VSA6 NEDD8;NEDD8-MDP1 NEDD8 0 ; 175.88 0.00014239 19124500.0 115713.0 101815.0 136566.0 118470.0 111361.0 113185.0 109557.0 100234.0 105539.0 97527.0 False True 114062.91140083477 101579.25362299505 125338.07064000466 127182.67900433484 104810.96492414984 108344.34139712168 115229.32539348192 104891.23756220726 93652.08644506054 114384.41200344091 0.9971892970643895 0.8880515434213129 1.0957618126868043 1.1118882090376871 0.9163046178092599 0.9471949848713868 1.0073866130466762 0.9170063973319365 0.8187486809150473 1.0 16.803530933392146 -6.310746781392526 24.998114255506263 0.9345755710065752 1.0187492178802773 0.2518729426427573 0.07480104593457022 610.7907153813032 309660.41761154734 0.024680492969259515 0.027985110477380077 4.88937354788776e-07 6.310746781392526 0.0841736468737021 EIEMS(ph)VDDDDINSSK ddPTM_PC-9_Lapatinib_30min_R1 1 EIEMSVDDDDINSSK 15 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 EIEMS(1)VDDDDINSSK 91.355 0.018491999999999998 0.0 11440.0 7241.4 10017.0 8876.0 9636.1 11759.0 9417.2 9378.6 8193.0 6746.0 True False 11276.863502160944 7224.632983210293 9193.440926738198 9528.770649468004 9069.32354330151 11256.09498156783 9904.77653728651 9814.363994262581 7270.218063885206 7912.037111520022 1.4252793993776514 0.9131191981760474 1.1619562442840967 1.2043384674717967 1.1462690853783364 1.4226544722823429 1.2518617389780737 1.2404345247537765 0.9188806828648061 1.0 12.949833477756119 -8.2596012113753 24.94872825017322 0.9594403208975433 1.213264624322202 0.3621755067145839 0.1384197967065431 171.397900644259 2326404.0857982575 0.10551512314430073 0.035287847887259624 5.5004571862588275e-09 8.2596012113753 0.2538243034246588 EIEMSVDDDDINS(ph)SK ddPTM_PC-9_Lapatinib_30min_R1 1 EIEMSVDDDDINSSK 15 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 EIEMSVDDDDINS(0.661)S(0.339)K 125.22 0.00045006 0.0 13772.0 18957.0 12068.0 14522.0 14304.0 14781.0 14862.0 15267.0 11698.0 10709.0 True False 13575.608754524521 18913.106231214606 11075.81562382715 15589.996323971876 13462.666842746015 14148.851086193894 15631.48163967551 15976.360554923636 10380.448054598952 12560.03638115445 1.0808574388282723 1.505816198079851 0.8818298998278157 1.241238150182725 1.0718652744466493 1.12649761965844 1.2445411116109164 1.2719995444356489 0.8264664002227068 1.0 13.616553022667134 -8.262363098772656 24.996365772702823 0.9132331888361591 1.178190799978095 0.30910336399226057 0.15838360580038413 97.19386020463328 2629908.8827861785 0.12066104646394382 0.03802356829062913 5.465588126742097e-09 8.262363098772656 0.26495761114193583 EIES(ph)SPQYR ddPTM_PC-9_AZD4547_30min_R2 2 EIESSPQYR 9 0 H3BUF6;Q8WWM7-7;H3BSK9;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 EIES(0.988)S(0.012)PQYR;EIES(0.5)S(0.5)PQYR 125.74 0.001417 55770000.0 128076.0 120836.0 137026.0 184359.0 149588.0 132623.0 110161.0 160659.0 98836.0 123416.0 True False 168801.5038537074 159893.87392323 135208.94570880197 141857.8808681565 128820.28827683278 124330.06284456106 119965.11558986522 135832.84312654583 104060.26918230686 119095.24340490706 1.417365622905745 1.3425714524938108 1.1353009729289574 1.1911296942889622 1.0816577101980633 1.0439548993729024 1.0073040044261106 1.1405396155473086 0.8737567194729734 1.0 16.861756268384525 -1.5228788957553054 0.323144786922832 0.9799434875402819 5.639230864475228 0.8206132985020199 0.06541697183706573 21.647909648682777 0.30878011981847864 0.057750200927554195 59.8074931316339 0.029999989605559264 1.5228788957553054 4.659287376934946 EIES(ph)SPQYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EIESSPQYR 9 0 H3BUF6;Q8WWM7-7;H3BSK9;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 EIES(0.5)S(0.5)PQYR;EIES(0.5)S(0.5)PQYR;EIES(0.871)S(0.129)PQYR 117.02 0.0018832 72337000.0 385670.0 402250.0 420640.0 426150.0 449800.0 393396.0 366017.0 331996.0 359398.0 271480.0 True False 450956.313670284 442182.7216223627 430669.6528860844 402274.1970969416 361664.91891631705 372765.62122592184 331345.2200263989 323281.4567788381 364653.5158357838 320697.17496550287 1.406174886694256 1.3788170153663746 1.3429168901547424 1.2543739967157923 1.1277458834965448 1.1623601650560842 1.0332028028062343 1.0080583242231966 1.137064945692176 1.0 18.290852119512877 -6.104492343474582 0.7982222962948173 1.0421684547773538 1.4269329331448009 0.9137704014031736 0.042644628068271385 0.19078738396342498 0.2514308377559375 0.02191866926693086 0.04611804118113578 7.861540507656571e-07 6.104492343474582 0.3847644783674471 EIES(ph)SPQYR ddPTM_PC-9_Lapatinib_30min_R1 3 EIESSPQYR 9 0 H3BUF6;Q8WWM7-7;H3BSK9;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 EIES(0.849)S(0.151)PQYR;EIES(0.639)S(0.361)PQYR;EIES(0.5)S(0.5)PQYR 117.71 0.001842 81201000.0 392572.0 316243.0 395873.0 323694.0 303464.0 289412.0 278883.0 244343.0 294246.0 225195.0 True False 386973.85129111167 315510.7587634126 363325.8500539705 347499.53657152987 285614.8441531789 277034.5234123229 293322.19715500064 255696.06779797623 261104.91693225532 264119.65569652454 1.4651459781385885 1.1945750797355907 1.3756107969163591 1.3156897984556266 1.0813842816808474 1.0488977909718225 1.1105655744608043 0.9681069253390703 0.9885857084118981 1.0 18.01083214481993 -6.30997577351823 3.0597378642959443 1.0286478521704383 1.3348468084691125 0.8138393517228291 0.07188054966717176 0.11194288663733126 2.0976228651231486 0.022998647525670456 0.02769044150085933 4.898061417248026e-07 6.30997577351823 0.3061989562986742 EIESS(ph)PQYR ddPTM_PC-9_AZD4547_30min_R2 1 EIESSPQYR 9 0 H3BUF6;Q8WWM7-7;H3BSK9;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 EIES(0.224)S(0.776)PQYR 133.91 0.001145 49651000.0 123620.0 107880.0 141820.0 173550.0 157650.0 152030.0 94327.0 164210.0 112070.0 143240.0 True False 162928.58854426473 142750.10029161867 139939.37413645815 133540.72882077133 135763.0187370822 142523.5400666447 102721.9202643881 138835.11767040775 117993.79140456048 138225.21119886308 1.178718318685447 1.0327356279907989 1.0124012321828102 0.9661097831758619 0.9821870956793941 1.0310965621285806 0.7431489478182327 1.0044124112110577 0.8536343723490798 1.0 17.076661250469655 -1.5228791829514752 0.4615534009264603 0.9183766235589246 7.0707854693052665 0.4648997484601598 0.07986120964557951 79.93859703022851 0.9376365300381916 0.04683404308217113 466.8315833311572 0.029999969766764122 1.5228791829514752 6.152408845746342 EIESS(ph)PQYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EIESSPQYR 9 0 H3BUF6;Q8WWM7-7;H3BSK9;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 EIES(0.414)S(0.586)PQYR 80.706 0.018298 34128000.0 55467.0 54339.0 69303.0 66383.0 57621.0 54779.0 53006.0 49260.0 45452.0 45490.0 True False 64856.46757681337 59733.41680605978 70955.44635309112 62663.775726589825 46330.5786858095 51906.29280708185 47984.88794979266 47966.97719528427 46116.649513264 53736.97690135813 1.2069243808758845 1.1115887094971675 1.3204212526383823 1.166120227448189 0.8621731507311227 0.9659325068167351 0.892958456481014 0.8926251523850045 0.8581921085348301 1.0 15.713627541017814 -6.2015042855682205 5.3735792674037635 0.9083810538722158 1.2072911157591646 0.8353803344967673 0.06300241072957194 0.07949843403471094 4.820569569774777 0.018290958702617297 0.02360286731668264 6.287756494013193e-07 6.2015042855682205 0.2989100618869488 EIESS(ph)PQYR ddPTM_PC-9_Lapatinib_30min_R1 1 EIESSPQYR 9 0 H3BUF6;Q8WWM7-7;H3BSK9;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 EIES(0.229)S(0.771)PQYR 108.35 0.0024416 33911000.0 186910.0 148870.0 213640.0 142920.0 147670.0 142020.0 121780.0 119730.0 147340.0 111170.0 True False 184244.6291249039 148525.30066154563 196075.34387424894 153430.81356714372 138984.34093039026 135946.13566478985 128085.17252588365 125293.09289585408 130745.01764101617 130385.58637528613 1.413075127756809 1.139123616271881 1.5038114973068368 1.1767467389035395 1.0659486588521718 1.0426469630891477 0.9823568393305281 0.9609428187501152 1.0027566794438112 1.0 16.992424868436572 -6.164013600029562 2.411608497840167 1.0005165489583505 1.3318448855097704 0.7351336582184431 0.0916776556985861 0.1497063121012344 1.7048791086771882 0.028297212970099343 0.038537745322799834 6.854667605704932e-07 6.164013600029562 0.3313283365514199 EIEVGGGR ddPTM_PC-9_Lapatinib_30min_R1 1 EIEVGGGR 8 0 P62081;B5MCP9 P62081 RPS7 40S ribosomal protein S7 0 93.195 0.034125 9586600.0 50567.0 54818.0 57949.0 53489.0 49412.0 66328.0 58296.0 59061.0 55726.0 54987.0 False True 49845.9053071479 54691.0722890079 53184.656909608806 57422.75949407323 46505.683307729705 63491.30605811981 61314.281635481275 61805.18967278083 49449.55105920505 64491.42968442806 0.7729074320581169 0.8480362825979259 0.8246779016972334 0.8903936503665135 0.7211141625374581 0.9844921467673752 0.9507353447660669 0.9583473335171565 0.7667615883408616 1.0 15.976819831972284 -6.775713853072602 24.99883447863099 0.9306307412922816 0.8185831003725281 0.40354178896537196 0.07306609428799204 262.0543305387528 458932.05080722395 0.025099440313785686 0.022237854198821627 1.676046822094284e-07 6.775713853072602 -0.1120476409197535 EIEVGGGRK ddPTM_PC-9_AZD4547_30min_R2 2 EIEVGGGRK 9 1 P62081;B5MCP9 P62081 RPS7 40S ribosomal protein S7 0 ; 104.01 0.0017284000000000002 21727900.0 42300.0 37050.0 55935.0 75858.0 69624.0 52078.0 44134.0 65425.0 46772.0 48972.0 False True 55750.52010534224 49025.68794776117 55193.265352720264 58370.11009441691 59957.909397720425 48821.554427354706 48061.84050111313 55315.06956693528 49244.27243306951 47257.5051859167 1.1797178011410674 1.0374159142529473 1.1679259227837637 1.2351500542566072 1.268748935472552 1.0330963142316727 1.0170202661361847 1.1705033803481406 1.042041306229278 1.0 15.528255848241022 -6.786133894754399 24.999989944428943 1.060969186951369 1.1726315868110742 0.43513457983479675 0.07091151075121492 271.71929344173975 275078.5533680353 0.026877745578839343 0.02371431102522341 1.6363119620226142e-07 6.786133894754399 0.11166239985970505 EIEVGGGRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EIEVGGGRK 9 1 P62081;B5MCP9 P62081 RPS7 40S ribosomal protein S7 0 ;;; 112.41 0.0013731 17274400.0 75754.0 68733.0 82438.0 92520.0 114046.0 98195.0 96335.0 99738.0 95408.0 77027.0 False True 88577.65599029887 75556.35799942772 84403.63456785596 87336.40435388697 91699.50498606094 93045.48133758201 87209.45139499837 97119.98318114626 96803.16150579708 90991.38535460361 0.9734729902737697 0.830368256346204 0.9276002803883637 0.9598315710166103 1.007782271131467 1.0225746203882198 0.9584363514758389 1.0673536049886352 1.0638717184988922 1.0 16.473442343602528 -6.0139603856161745 1.6576606327370955 1.0230808497737043 0.8985101015163927 0.5649114067120408 0.04359762297273257 0.2627242932780029 1.4539085960606248 0.01473994756070888 0.024472845294166497 9.683661822283265e-07 6.0139603856161745 -0.12457074825731163 EIEVGGGRK ddPTM_PC-9_Lapatinib_30min_R1 3 EIEVGGGRK 9 1 P62081;B5MCP9 P62081 RPS7 40S ribosomal protein S7 0 ;; 112.41 0.0013731 23376200.0 112865.0 100072.0 102723.0 97729.0 104361.0 91725.0 79640.1 70338.0 104994.0 76666.0 False True 111255.5244030939 99840.28943240522 94277.51146224691 104916.31667438678 98222.69116162039 87802.13557141848 83763.47469599797 73606.16026149325 93168.47008416489 89917.61594897637 1.2373050956580711 1.1103529422872984 1.048487668042095 1.1668049198937993 1.092363160710986 0.9764731264810411 0.9315580024222333 0.8185955497670331 1.0361536958123223 1.0 16.456316164394487 -6.774517427341376 2.616601687516395 0.9329100461557902 1.1325364013160244 0.6275177316475606 0.06936380799829184 0.17727846881097648 2.488073439874021 0.026003272341060375 0.023909033488335736 1.6806704825172303e-07 6.774517427341376 0.1996263551602342 EIEY(ph)VETVTSR ddPTM_PC-9_AZD4547_30min_R2 1 EIEYVETVTSR 11 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 EIEY(0.986)VET(0.014)VTSR 92.538 0.01645 0.0 4502.7 4788.8 6728.2 7581.3 7841.3 7761.9 5647.3 7055.3 5963.9 6065.6 True False 5934.464938021851 6336.68594991197 6638.979671872217 5833.548414917384 6752.670845690354 7276.547165975739 6149.898759730277 5965.065499665241 6279.139578456835 5853.245190224953 1.0138760200807129 1.0825936286582312 1.1342391196868804 0.9966348965971111 1.153662733446988 1.243164591520569 1.050681896941673 1.0191039851921855 1.072762095963985 1.0 12.515020998545047 -7.501500989702219 24.857907096199447 1.0345383762490243 1.1055620741370142 0.20037754237251748 0.06764738263297464 1247.4738532101987 1450558.1786967514 0.03001826284230612 0.02001821730084271 3.1513671986288874e-08 7.501500989702219 0.0710236978879899 EIFDSR ddPTM_PC-9_AZD4547_30min_R2 1 EIFDSR 6 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798 P06733 ENO1 Alpha-enolase;Enolase 0 132.96 0.030378 20288000.0 84244.0 80162.0 118080.0 154600.0 136060.0 118440.0 100740.0 131650.0 93188.0 106150.0 False True 111031.8396159447 106072.79884665125 116514.18204789868 118959.35854618982 117170.41756655513 111033.92807665194 109705.66484076058 111306.51751604205 98113.72743292745 102433.72080954534 1.0839383626646328 1.0355261725176619 1.1374592382964697 1.1613300542637766 1.143865678611926 1.083958751074726 1.0709917005234628 1.0866198809959648 0.9578264526322339 1.0 16.644331197941867 -8.186220774432941 4.608035343592708 0.979024281681743 1.1026558026801356 0.6354813309311429 0.0368771123302705 0.14611584653064927 5.62512988725834 0.030939798409257247 0.01065191034472343 6.5129722169994926e-09 8.186220774432941 0.12363152099839259 EIFDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EIFDSR 6 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798 P06733 ENO1 Alpha-enolase;Enolase 0 143.18 0.0051727 44572000.0 64142.0 62982.0 74838.0 84170.0 87426.0 82154.0 78730.0 69931.0 72401.0 58302.0 False True 74999.9737377533 69234.43672646262 76622.42174469554 79454.22778282186 70295.50289279222 77845.69961614854 71272.12444416074 68095.38534801904 73459.72765576508 68871.69108162182 1.0889811555355695 1.0052669774640919 1.1125387011898418 1.153655827742902 1.0206733969909787 1.1303003947426145 1.0348537014968038 0.9887282318553389 1.0666171615955509 1.0 16.071623481076294 -7.501705950283412 22.727465533227754 1.0189618059654808 1.0829807840055365 0.30762651506254857 0.04648664378871973 301.4788256885845 323618.47935044416 0.01955034955337694 0.012993359562443199 3.149880295872162e-08 7.501705950283412 0.06401897804005574 EIFSGS(ph)LR ddPTM_PC-9_AZD4547_30min_R2 1 EIFSGSLR 8 0 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 EIFS(0.001)GS(0.999)LR 81.525 0.017759999999999998 2008800.0 4518.6 7020.2 8663.1 11292.0 13946.0 7331.8 6507.4 16704.0 11823.0 12277.0 True False 5955.420807281308 9289.342362506686 8548.221633631021 8688.80385966089 12009.838625482724 6873.341386967228 7086.545993495801 14122.780619733858 12447.939642867115 11847.185966827974 0.5026865302829244 0.7840969482978296 0.7215402592283073 0.7334065561213836 1.013729223050113 0.5801665818543348 0.598162805356316 1.1920789172447812 1.0507085545648769 1.0 13.532256799532037 -7.763065491815103 24.99998651418335 1.0910453523103252 0.7167040770202378 0.6067459437374589 0.13845230284851717 29.88881443091966 459483.06969460717 0.07211572715992365 0.037515415737143384 1.72557765443504e-08 7.763065491815103 -0.3743412752900874 EIFSGS(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 1 EIFSGSLR 8 0 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 EIFS(0.001)GS(0.999)LR 78.939 0.021419 2405300.0 9165.5 7585.8 10431.0 13456.0 7169.5 5487.0 4957.2 5423.0 10543.0 10337.0 True False 9034.79828925315 7568.235546170163 9573.40344482441 14445.599127900115 6747.804105779331 5252.33380082173 5213.859560234114 5674.972377634826 9355.536317288148 12123.736676813303 0.7452156484503858 0.6242494164892615 0.7896413209908776 1.1915137645250398 0.5565779169952226 0.4332273077876097 0.43005384389498014 0.46808772979111585 0.7716710257474207 1.0 13.565546802308813 -4.71770670908687 20.409216680657984 0.6770053563068112 0.7452221099988356 0.0 0.2391732055180922 8468.677692004592 3949633.140663651 0.06394454169702841 15.63350319923452 1.9155491108894402e-05 4.71770670908687 0.0682167536920244 EIGRY(ph)HWMYPGS(ph)K ddPTM_PC-9_AZD4547_30min_R2 2 EIGRYHWMYPGSK 13 1 B7Z613 B7Z613 GPM6B 2 EIGRY(0.99)HWMY(0.01)PGS(1)K;EIGRY(0.999)HWMY(0.001)PGS(1)K 84.89200000000001 0.029552 19806600.0 25847.0 32819.0 34535.0 40719.0 38472.0 46869.0 40266.0 44636.0 43656.0 35744.0 True False 34065.80834900188 43427.099939475636 34077.04333523186 31331.863652278767 33130.826875058876 43938.27402080894 43849.595994422045 37738.53183323995 45963.56703450962 34492.61343962685 0.9876261886803093 1.2590260814967529 0.9879519101931091 0.9083644446692793 0.9605194727575067 1.2738458945047764 1.2712749664844305 1.0941047392449543 1.3325626112663402 1.0 15.07399982274508 -6.760772088525389 24.99998905734017 1.2050465269161266 1.0258781458031876 0.3250712923789649 0.12452827759521841 22.064585656635227 826657.7337039312 0.0429149388785729 0.040509001210190916 1.7347141118493804e-07 6.760772088525389 -0.17916838111293898 EIGRY(ph)HWMYPGS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 EIGRYHWMYPGSK 13 1 B7Z613 B7Z613 GPM6B 2 EIGRY(0.999)HWMY(0.001)PGS(1)K 88.22399999999999 0.023708 7110700.0 18823.0 20447.0 18985.0 19293.0 20426.0 22327.0 14974.0 18722.0 20426.0 15709.0 True False 18554.58056828455 20399.65622775994 17424.12658421928 20711.871579561313 19224.582839061102 21372.126256779055 15749.280451655304 19591.892468021248 18125.408784684398 18424.27971907325 1.0070722357236257 1.1072159421592875 0.9457154824989665 1.1241618068857202 1.0434374169406124 1.1599979257074633 0.8548111889199813 1.0633735899992476 0.9837784196209607 1.0 14.169320599085097 -7.248681497688982 24.978445430591456 0.9807719215427293 1.0628787679520086 0.2545124546984032 0.07445872001184435 1131.5874253405862 2215519.297503392 0.02725731307899925 0.020970249310945183 5.6405116727398654e-08 7.248681497688982 0.08210684640927934 EIHKPGYLANDR ddPTM_PC-9_AZD4547_30min_R2 1 EIHKPGYLANDR 12 1 A0A2R8Y7M3;A0A2R8Y5S7;P35241;P35241-5;E9PNV3;A0A2R8Y5P0;P35241-3 A0A2R8Y7M3 RDX Radixin 0 67.749 0.016287 7611700.0 10987.0 6746.6 11019.0 15364.0 17451.0 12737.0 14016.0 18990.0 12521.0 15054.0 False True 14480.637456203183 8927.306513046298 10872.8808603133 11822.067171433762 15028.229876186646 11940.553376497111 15263.3968474102 16055.531846787942 13182.834497871869 14526.964042080981 0.9968109932850663 0.6145335313824778 0.7484620206133424 0.8138016406723518 1.0345058907459002 0.8219579357330489 1.0506941989527858 1.1052227981207279 0.9074734720678385 1.0 13.826445608392094 -6.151948448368072 4.464793982774352 0.9866479092064452 0.771144641455673 0.40537769229866305 0.11423144642091668 0.21950546964248838 7.173698486269508 0.033933030168219754 0.04450916086399019 7.047767224221655e-07 6.151948448368072 -0.21550326775077222 EIHQDWANR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EIHQDWANR 9 0 Q8WUW1;Q8WUW1-2 Q8WUW1 BRK1 Protein BRICK1 0 ; 119.75 0.0014425 7138900.0 28210.0 25614.0 36031.0 34728.0 40291.0 31346.0 36483.0 31506.0 31282.0 26559.0 False True 32985.39582710267 28156.78864297125 36890.11568832844 32782.3027496951 32396.267781363553 29702.160578520743 33027.06612595337 30679.000883366356 31739.44007027027 31373.936459071665 1.051362995846352 0.8974579482463958 1.1758204373382606 1.0448896902835478 1.0325853698220353 0.9467145003391012 1.052691177883855 0.9778499081040762 1.0116499123938565 1.0 14.937278933713117 -6.546732308290493 24.91526361200186 0.9986976258417233 1.0412091878127876 0.09274942751341542 0.06717357183541647 608.6358835246147 635720.7080801325 0.022112696525072736 0.022113359269913032 2.839668812528433e-07 6.546732308290493 0.042511561971064316 EIHQDWANR ddPTM_PC-9_Lapatinib_30min_R1 1 EIHQDWANR 9 0 Q8WUW1;Q8WUW1-2 Q8WUW1 BRK1 Protein BRICK1 0 114.89 0.0016883 6583700.0 16151.0 20799.0 22451.0 18933.0 20817.0 19515.0 18458.0 17975.0 20424.0 16848.0 False True 15920.683778269355 20750.841193386757 20605.165443366204 20325.39597863652 19592.584987796687 18680.388941686895 19413.66492431237 18810.184120963677 18123.634045745337 19760.15435145114 0.8056963268153914 1.05013558215768 1.0427633851884872 1.0286051220619068 0.9915198352870079 0.9453564283679318 0.9824652469319742 0.9519249590063198 0.9171807933987307 1.0 14.27030659576371 -6.743951635296593 20.992503098229143 0.9578233336757155 0.993203695969875 0.021613763970019684 0.06807395904647105 123.95960164517001 148798.981773642 0.022450780293017364 0.022359189450747576 1.8032185430288029e-07 6.743951635296593 0.03538036229415953 EIHQFNR ddPTM_PC-9_AZD4547_30min_R2 2 EIHQFNR 7 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 ; 114.02 0.0074218 15690200.0 40112.9 37481.0 42686.0 58712.0 50767.0 44840.0 44167.0 51273.0 39850.0 45140.0 False True 52867.967799848266 49596.000269096796 42119.95574946305 45176.85549135764 43718.87835220717 42036.1477115593 48097.777437183686 43349.93598632745 41956.38964461262 43559.66233954665 1.213690946172713 1.1385763250985974 0.9669486283235825 1.0371259340626886 1.003655125042509 0.9650246455973054 1.1041815949412674 0.995185308104907 0.9631936381316145 1.0 15.410705150340963 -5.079324264664695 3.650973321896982 1.0078107270065673 1.203417017065808 0.7504779320046696 0.04051497322176544 0.10865592867554814 2.678995535668 0.010526911481158745 0.03676114245751643 8.330589514014454e-06 5.079324264664695 0.1956062900592408 EIHQFNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EIHQFNR 7 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 ;; 114.72 0.0071671999999999994 12625600.0 31524.5 32119.8 39427.0 41507.0 42681.0 37530.4 41666.0 35291.0 35370.3 29977.8 False True 36860.975212743644 35308.44147163692 40367.08920773017 39181.49735750965 34317.96443812211 35562.23975550675 37719.09484428294 34364.648643905355 35887.52372346657 35412.53783586577 1.0409018236306944 0.9970604658521983 1.1399095256834837 1.1064300880979698 0.96909079482479 1.0042273705526228 1.065133908761577 0.9704090907910273 1.013412929900769 1.0 15.111972617574263 -6.261166122128276 24.99999880249706 1.0053296329022012 1.070705406946928 0.36917670033695316 0.043106270166688936 30.322068768500248 2774040.3551964276 0.013871381230052457 0.01682772519575841 5.480672834199072e-07 6.261166122128276 0.06537577404472672 EIHQFNR ddPTM_PC-9_Lapatinib_30min_R1 3 EIHQFNR 7 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 ;; 101.21 0.00946 19167400.0 47814.0 44593.6 41219.2 40366.4 45175.3 42288.9 34122.7 35587.3 41686.0 40098.6 False True 47132.1635919863 44490.34625902264 37830.316486713295 43335.079714362924 42518.177672057034 40480.30232724072 35889.4064423466 37240.815875825894 36990.88370695946 47029.58958197407 1.0021810526292907 0.9460075381154359 0.8043939320536457 0.9214428639405517 0.904072904951605 0.8607411352523557 0.7631239558191385 0.7918592572642797 0.7865448972818097 1.0 15.521281121682952 -6.917004136463483 3.511249598501507 0.8172349352244452 0.9115442516287394 0.18102004479145284 0.07689280954195372 0.3485658280741096 8.52683255567274 0.02844385825103101 0.024502606033775676 1.2105866031918598e-07 6.917004136463483 0.09430931640429419 EIIDLVLDR ddPTM_PC-9_AZD4547_30min_R2 2 EIIDLVLDR 9 0 Q9BQE3;F5H5D3;A0A1W2PQM2;F8VVB9;F8VQQ4;F8VRZ4;F8VS66;P68363;Q71U36-2;Q71U36 Q9BQE3;P68363;Q71U36-2 TUBA1C;TUBA1B;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-1B chain;Tubulin alpha-1A chain 0 ; 155.58 0.00036397 36173000.0 148137.0 142724.0 162489.0 188525.0 170730.0 174857.0 167920.0 189780.0 150682.0 171714.0 False True 195241.48455898513 188856.741880061 160334.28969157342 145063.4739322148 147027.086514317 163923.16414808508 182864.5546958559 160453.86171055379 158646.74289660025 165702.34512567398 1.1782662726403041 1.1397348766357287 0.9676042277492859 0.8754461128609496 0.8872963530045814 0.989262789393599 1.1035725206976736 0.9683258350318483 0.9574200218848892 1.0 17.33823449508452 -5.225955704785251 4.46550373533935 0.9663110522499722 1.166375135405658 0.6227380934293637 0.05948105080300709 0.1446860409908425 6.90746314043144 0.017507624121978083 0.047848323123400045 5.943527756447673e-06 5.225955704785251 0.2000640831556858 EIIDLVLDR ddPTM_PC-9_Lapatinib_30min_R1 4 EIIDLVLDR 9 0 Q9BQE3;F5H5D3;A0A1W2PQM2;F8VVB9;F8VQQ4;F8VRZ4;F8VS66;P68363;Q71U36-2;Q71U36 Q9BQE3;P68363;Q71U36-2 TUBA1C;TUBA1B;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-1B chain;Tubulin alpha-1A chain 0 ;;; 168.26 0.00036397 104843800.0 329007.0 310737.0 398210.0 348097.0 366102.0 404661.0 370698.0 369196.0 403081.0 356096.0 False True 324315.29984750494 310017.50756812457 365470.71093505237 373697.2145975521 344568.6001442252 387354.5923408636 389890.92860075587 386350.1939762615 357681.7731488968 417646.7191319056 0.7765302227720272 0.7422960443996965 0.8750714280593345 0.894768706370532 0.8250240798261841 0.9274694965783394 0.9335424193231036 0.9250645971296144 0.8564218435436338 1.0 18.671923579280232 -2.037096177447292 0.22983972786171158 0.9625967197752822 2.7408431439167536e-19 0.6591539710668768 0.04323742648146911 24.843764076575457 0.40011092269231296 0.06450996164849496 8.568991012277332 0.00918129248042726 2.037096177447292 -0.9625967197752822 EIIDPVLDR ddPTM_PC-9_AZD4547_30min_R2 2 EIIDPVLDR 9 0 P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8 P68366-2 TUBA4A Tubulin alpha-4A chain 0 ; 126.24 0.006453699999999999 7516500.0 70035.0 62329.0 82242.0 107559.0 97277.0 88066.0 75362.0 99110.0 68666.0 76838.0 False True 92304.67318150436 82475.63033997317 81151.41734403188 82762.93431998452 83771.76767324546 82559.2190982646 82069.07200446111 83794.82682122986 72295.54457558261 74147.92500766696 1.2448719660322252 1.1123120482662883 1.0944529780926542 1.1161867889280348 1.1297924744972079 1.1134393725748617 1.1068289772906672 1.1301034629433717 0.9750177711393433 1.0 16.17811869970022 -1.5228787499916494 0.060763079669746825 0.8250855448956076 1.6920794731919482 0.5649765217132425 0.04617928412298198 273.12434247266606 1.243629120105374 3.560088884290997 20.906952514930733 0.02999999967455411 1.5228787499916494 0.8669939282963406 EIIDPVLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EIIDPVLDR 9 0 P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8 P68366-2 TUBA4A Tubulin alpha-4A chain 0 ; 114.89 0.0092685 3818100.0 43924.0 54568.0 53921.0 60921.0 62690.0 53098.0 58984.0 50312.0 45103.0 43984.0 False True 51359.46566145547 59985.15041265148 55206.681136531224 57507.79387854684 50406.34452393048 50313.44740631322 53396.6085128206 48991.3633099704 45762.54604850715 51957.95102284761 0.9884813517544415 1.1544941482829847 1.0625261398829036 1.106814120773523 0.9701372654546205 0.9683493366431782 1.0276888803667483 0.9429040665677386 0.8807611760591535 1.0 15.665056918351752 -6.270847477152124 23.454580943870393 0.9654232062669779 1.0824262546725767 0.5242893721575044 0.05271464149246943 223.9587685163682 558332.4012414487 0.01607804358192752 0.01850187155592642 5.359848606503637e-07 6.270847477152124 0.11700304840559883 EIIDPVLDR ddPTM_PC-9_Lapatinib_30min_R1 3 EIIDPVLDR 9 0 P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8 P68366-2 TUBA4A Tubulin alpha-4A chain 0 ;; 110.87 0.010472 18976060.0 115623.0 116368.0 115821.0 107220.2 118401.0 106609.8 113468.0 108021.0 121626.0 92664.0 False True 113974.1948173388 116098.55704562858 106298.64446198908 115105.53118410212 111436.88596532223 102050.34737358196 119342.817836812 113040.05001004852 107927.19910144055 108680.84893298148 1.0487054153176654 1.068252209892299 0.9780807336860113 1.0591151275886928 1.0253589943343218 0.9389910768594728 1.0981034746094527 1.0401101124978804 0.993065477138427 1.0 16.72973821440101 -5.219304279585825 24.872971234967327 1.0200054645804333 1.0584788326610237 0.13291162036487258 0.04207108150947095 1011.6315629843338 597177.5702800009 0.010607073392791619 0.028063383326877408 6.035256332656634e-06 5.219304279585825 0.03847336808059043 EIIKQEES(ph)VDPDYWEK ddPTM_PC-9_AZD4547_30min_R2 1 EIIKQEESVDPDYWEK 16 1 Q14839-2;A0A2R8Y8C1;A0A0C4DGG9;A0A2R8Y521;A0A2R8Y212;F5GWX5;A0A2U3TZM0;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8YER1;Q14839;A0A2R8YDJ9;A0A2R8YD40;A0A2R8YE38;A0A2R8YDW2;A0A2R8YFD8;A0A2R8Y5M9;A0A2R8Y5Z7;A0A2R8Y4X2 Q14839-2 CHD4 Chromodomain-helicase-DNA-binding protein 4 1 EIIKQEES(0.993)VDPDY(0.007)WEK 105.38 0.0016692 0.0 14650.0 16630.0 16604.0 17321.0 11849.0 20493.0 18876.0 18463.0 19327.0 12501.0 True False 19308.39526107005 22005.322282625304 16383.820111139124 13327.911056782357 10203.970878627902 19211.56947040554 20555.92743234268 15609.967587532703 20348.5857631475 12063.34379500827 1.6005840162708231 1.8241478197554941 1.3581491491537063 1.1048272587818775 0.8458658769925994 1.5925575691836915 1.703999138352385 1.2940000594190146 1.6868113939990343 1.0 13.558342237685471 -5.293093992041585 10.57208984087494 1.3320187139870547 1.7122778486614292 0.24184560337464567 0.2752161897312071 1.000411116682649 332.47729842798066 0.07628054450425789 0.16045247933630155 5.0922065121714065e-06 5.293093992041585 0.38025913467437444 EILDAFDK ddPTM_PC-9_AZD4547_30min_R2 2 EILDAFDK 8 0 C9JIZ6;P07602;P07602-2;P07602-3;A0A0J9YXB8 C9JIZ6 PSAP Prosaposin;Saposin-A;Saposin-B-Val;Saposin-B;Saposin-C;Saposin-D 0 ; 122.52 0.015321000000000001 4968400.0 33542.0 34782.0 41507.0 47031.0 42917.0 39550.0 42366.0 48280.0 40271.0 41622.0 False True 44207.65828305884 46024.60130091845 40956.590059808004 36188.72957170663 36958.71535134391 37076.93224781825 46136.49192618297 40819.4353640296 42399.642845124035 40164.82644875079 1.1006560264729786 1.1458931948739919 1.0197128602576555 0.9010055008673434 0.9201761496094651 0.923119443703495 1.1486789812238292 1.0162980640813692 1.055641131655948 1.0 15.293645022227013 -5.350676233347331 5.045410611406391 0.9937836474125629 1.12269483545264 0.34284074227834216 0.06973974974011515 0.24912837774939284 10.39971619344376 0.020306586446420034 0.04410465577197393 4.459886091222511e-06 5.350676233347331 0.12891118804007717 EILDAFDK ddPTM_PC-9_Lapatinib_30min_R1 2 EILDAFDK 8 0 C9JIZ6;P07602;P07602-2;P07602-3;A0A0J9YXB8 C9JIZ6 PSAP Prosaposin;Saposin-A;Saposin-B-Val;Saposin-B;Saposin-C;Saposin-D 0 ; 163.99 0.00043991 14786400.0 101257.0 94292.0 99613.0 95392.0 92192.0 92589.0 97773.0 90617.0 96088.0 103951.0 False True 99813.05661174029 94073.67266728342 91423.2036572997 102407.44589838364 86769.44781644575 88629.18430550091 102835.20753303671 94827.39663362243 85265.55758850262 121918.79184399892 0.8186847581253593 0.7716092920905524 0.7498696654924221 0.8399644086813048 0.7116987176798104 0.7269526130057645 0.8434729870405819 0.7777914724988313 0.6993635378014907 1.0 16.8955609860445 -10.508624028586981 5.258530179809136 1.0000010579751255 0.7717523979851065 0.6687320546624225 0.048340795338849885 5.949296943299155e-07 1.1470332907999107e-07 0.04639303959735789 0.011251912545837182 3.100101915229195e-11 10.508624028586981 -0.22824865999001898 EILDESLR ddPTM_PC-9_AZD4547_30min_R2 1 EILDESLR 8 0 Q8WUM4;Q8WUM4-2 Q8WUM4 PDCD6IP Programmed cell death 6-interacting protein 0 95.90899999999999 0.025518 0.0 6424.5 7343.9 8892.9 11108.0 11648.0 11024.0 8235.6 11402.0 8386.0 7805.0 False True 8467.357362098606 9717.67205720818 8774.974335482362 8547.222216889233 10030.876259115355 10334.667537293257 8968.55244552878 9640.082891894479 8829.266839641683 7531.749325657111 1.124221876749711 1.290227759453526 1.1650645761125071 1.1348256357620514 1.3318122823000629 1.37214703921278 1.1907661895991626 1.2799261466463405 1.1722730613941894 1.0 12.878769269127037 -8.615770930126565 4.465110363201261 1.0000240652732195 1.2380549035063033 0.44836875053573166 0.07903154236433733 0.513316463038129 22.753999547611176 0.07847145068993867 0.02047259010089262 2.4223063623016044e-09 8.615770930126565 0.2380308382330838 EILDESLR ddPTM_PC-9_Lapatinib_30min_R1 3 EILDESLR 8 0 Q8WUM4;Q8WUM4-2 Q8WUM4 PDCD6IP Programmed cell death 6-interacting protein 0 ;; 122.18 0.0021736999999999998 2231570.0 30144.4 36400.0 35822.3 32736.0 35894.2 38573.0 34990.6 31997.9 36938.8 30293.8 False True 29714.535328194062 36315.71803640935 32877.128772076816 35143.51464409472 33782.973726712386 36923.32270805477 36802.2420576793 33484.63924807698 32778.36336119161 35530.04296604883 0.8363214014851643 1.0221129783353002 0.9253332117693458 0.9891210848710917 0.950828394972506 1.039214130513079 1.0358062919554063 0.9424317127922879 0.9225534399863624 1.0 15.116751812853206 -4.750998525054181 24.994526625124568 0.9801543293537738 0.8363211016056885 0.5188078134177168 0.04174471637829221 376.42146812651777 901061.3284592159 0.010681444750224466 0.14722748284018916 1.7741955063818777e-05 4.750998525054181 -0.14383322774808527 EILFYDR ddPTM_PC-9_Lapatinib_30min_R1 1 EILFYDR 7 0 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 0 123.69 0.021516 4040700.0 23289.0 21249.0 25376.0 21541.0 24535.0 22753.0 17788.0 17664.0 22709.0 19407.0 False True 22956.894589320473 21199.799246034672 23289.68323419273 23125.19699866949 23091.899537665915 21779.907229833556 18708.975602647555 18484.73392560235 20151.27328362861 22761.474091797965 1.008585581792039 0.9313895559020038 1.0232062800618482 1.0159797605991867 1.014516873754983 0.9568759537275262 0.8219579947763261 0.8121061865788066 0.8853237361674244 1.0 14.474306372873254 -7.082599000362764 4.619029343517844 0.865023209636158 0.9965937775629723 0.5108094240444034 0.054042683713507914 0.16397935922568474 6.213640355235514 0.020550677972659453 0.015971712774941686 8.26801012204743e-08 7.082599000362764 0.13157056792681432 EILGTAQSVGCNVDGR ddPTM_PC-9_AZD4547_30min_R2 1 EILGTAQSVGCNVDGR 16 0 P30050;P30050-2 P30050 RPL12 60S ribosomal protein L12 0 89.663 0.017049 3490700.0 8431.1 12742.0 17422.0 18649.0 16404.0 15299.0 10210.0 13567.0 11054.0 12687.0 False True 11112.014422225786 16860.602316609245 17190.972896667427 14349.761174177827 14126.587753651133 14342.35111148853 11118.670220609167 11470.531888645184 11638.291872811735 12242.831991622255 0.9076343144976354 1.3771815482028114 1.404166365137672 1.1720949192145527 1.1538660142782264 1.171489661975511 0.908177963090374 0.9369181817159988 0.9506208923536478 1.0 13.579649698011723 -7.164585547816157 3.6792017102833476 0.9430586494404626 1.2181655628084196 0.46682454519023087 0.12964395420262473 0.2151690522197335 5.384470596492247 0.05409041953458875 0.04054773362074212 6.845646234986648e-08 7.164585547816157 0.275106913367957 EILHCLK ddPTM_PC-9_Lapatinib_30min_R1 2 EILHCLK 7 0 Q08J23;A0A140T9Y7 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 0 ; 102.71 0.0090549 3443500.0 97044.0 86506.0 94805.0 81471.0 86840.0 83729.0 78498.0 72817.0 84201.0 73238.0 False True 95660.13476430997 86305.70067191283 87010.4988578831 87462.64911928873 81732.2419340089 80148.10585183198 82562.24234633624 76200.34365152763 74717.39670416198 85897.09071649915 1.113659775510133 1.0047569708357444 1.012962117018127 1.018225977035202 0.9515135058970016 0.9330712505311556 0.961176236094311 0.8871120432125535 0.8698478153441142 1.0 16.390321648515553 -5.163976163054868 0.5041243941729777 0.9159858256100348 1.15894023523219 0.6385575029794973 0.04047653121200194 2.0093795833309795 0.5184113869996401 0.02716153495717093 0.2763996078428071 6.855258515995458e-06 5.163976163054868 0.2429544096221552 EILIPVFK ddPTM_PC-9_Lapatinib_30min_R1 1 EILIPVFK 8 0 P53396;P53396-2;P53396-3 P53396 ACLY ATP-citrate synthase 0 139.31 0.012713 22027000.0 82732.0 77758.0 91558.0 81053.0 108670.0 105080.0 94934.0 85222.0 91359.0 97786.0 False True 81552.22650880922 77577.95612843712 84030.45466410047 87013.90800488186 102278.24425344015 100585.97335344409 99849.2180043705 89181.7252382068 81069.18736708026 114688.17980834539 0.7110778690976749 0.676425035762858 0.7326862698886945 0.7586998777929006 0.8917941188390696 0.8770387107157216 0.8706147239517431 0.777601714381009 0.7068661086308494 1.0 16.807357183919393 -5.970014195958192 2.7378993634632893 0.8444832443057171 0.7020327199043538 0.45139006516240854 0.07330026327737493 0.2708716578922538 4.123305747226035 0.022731107734983057 0.03482397917514527 1.0714842806280675e-06 5.970014195958192 -0.1424505244013633 EILSEVER ddPTM_PC-9_AZD4547_30min_R2 2 EILSEVER 8 0 P49368-2;P49368;B4DUR8 P49368-2 CCT3 T-complex protein 1 subunit gamma 0 ; 113.41 0.017113999999999997 7334400.0 16075.1 17909.5 28327.0 38509.0 33926.0 31432.0 22367.5 39466.0 23457.3 29422.0 False True 21186.64741714863 23698.395635639103 27951.365471466986 29631.34500811915 29215.960505386985 29466.552071135848 24358.16416841092 33367.436538458845 24697.20498897291 28391.944735359823 0.7462203668902754 0.834687297982963 0.98448224424218 1.043653236307401 1.0290228717232222 1.037849021819125 0.8579251754486137 1.1752430786082244 0.8698666195350324 1.0 14.793194050872021 -5.13600346387781 2.4473029437050595 1.0069753331219637 0.7496493316539736 0.5045152113122031 0.08512775570958632 0.24251474438912202 2.6263752555214532 0.021440789321680705 0.09303786845747804 7.311332520338992e-06 5.13600346387781 -0.2573260014679901 EILSEVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EILSEVER 8 0 P49368-2;P49368;B4DUR8 P49368-2 CCT3 T-complex protein 1 subunit gamma 0 ; 143.89 0.0077832 5638800.0 18098.8 18432.9 23828.0 24507.0 26321.0 18800.3 25859.0 22457.1 23309.0 17663.1 False True 21162.569372405735 20262.796493207803 24396.149888193224 23133.95224276601 21163.588996879447 17814.379171963366 23409.44831705255 21867.624920264283 23649.850028704357 20865.280208977318 1.014248031200679 0.9711250599208203 1.1692222507367405 1.108729526326351 1.0142968982402538 0.8537809697997107 1.1219330908856235 1.0480388809183452 1.1334547052250452 1.0 14.348816674863794 -10.637488428658378 4.090127008762851 0.9999889743685588 1.0468122034005096 0.02628362547764007 0.08779340601456512 64881453.244443975 0.1646462344263726 6840.2428806827875 0.022043325717510026 2.304154367124012e-11 10.637488428658378 0.0468232290319508 EILSEVER ddPTM_PC-9_Lapatinib_30min_R1 4 EILSEVER 8 0 P49368-2;P49368;B4DUR8 P49368-2 CCT3 T-complex protein 1 subunit gamma 0 ;;; 148.99 0.0037336999999999995 21826400.0 75641.0 74322.0 84985.0 74366.0 79128.0 79055.0 72568.0 70094.0 79779.0 65225.0 False True 74562.34546913963 74149.91197533003 77997.86135158678 79835.12371770383 74473.84661163349 75674.00193620587 76325.21596204906 73350.82313072743 70793.44890988625 76499.05434315048 0.9746832311766446 0.9692918770304932 1.0195924906694027 1.0436092890715851 0.973526369065524 0.9892148678957038 0.9977275747707725 0.9588461420934553 0.9254160004688334 1.0 16.22315429333017 -7.774766920325155 7.493824858751823 0.9563699249340696 0.9961135043159854 0.24013838745153904 0.027226071451851606 0.19741959270264034 57.88571998032174 0.014816177993999759 0.007481259207078484 1.679705250192102e-08 7.774766920325155 0.03974357938191586 EIPFNEDPNPNTHS(ph)SGPSTPLK ddPTM_PC-9_AZD4547_30min_R2 1 EIPFNEDPNPNTHSSGPSTPLK 22 0 Q86YS7-3;Q86YS7;H0YFE9 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 EIPFNEDPNPNT(0.003)HS(0.555)S(0.383)GPS(0.03)T(0.03)PLK 84.12700000000001 0.00013301 5884300.0 14412.0 16524.0 28524.0 34570.0 28963.0 28816.0 26384.0 30820.0 26563.0 26678.0 True False 18994.7162117776 21865.05985556828 28145.753122749495 26600.4206011758 24941.98738777113 27014.130964680935 28732.12488741944 26057.477173144 27967.06595056072 25744.011340151214 0.73783047873945 0.8493260652611199 1.0932932226786447 1.033266348810564 0.9688461933230575 1.0493365081201933 1.1160702389300095 1.0121762622324477 1.086352300775379 1.0 14.651949246225945 -5.084051788454899 3.4671526712547167 1.0446398403372563 0.7518430085207723 0.8457101834398248 0.0439935656329729 0.08443157979024943 1.8703262203223894 0.01170205152731812 0.04207449356373908 8.240398446073406e-06 5.084051788454899 -0.29279683181648397 EIPFNEDPNPNTHS(ph)SGPSTPLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EIPFNEDPNPNTHSSGPSTPLK 22 0 Q86YS7-3;Q86YS7;H0YFE9 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 EIPFNEDPNPNT(0.003)HS(0.95)S(0.04)GPS(0.003)T(0.004)PLK 106.89 1.8674e-05 6251100.0 20707.0 23400.0 28194.0 35794.0 33958.0 17653.0 20635.0 15526.0 16141.0 12551.0 True False 24212.28611810761 25722.997354787527 28866.25188634044 33788.57822571375 27304.17366954268 16727.245603669584 18680.303415537317 15118.458951156805 16377.031589228072 14826.39694633867 1.6330526024454484 1.7349459513249939 1.9469498888243963 2.2789473631392103 1.841591977360714 1.1282070528807961 1.259935470711268 1.0196987849357602 1.1045860736429511 1.0 13.855880421764777 -6.749454064946555 5.369311407925153 1.1093534970892254 1.9093514403369187 0.842386306870632 0.1697747858737317 0.07210692467578415 6.148092643144762 0.06400783219242928 0.06084464092769547 1.780516222972568e-07 6.749454064946555 0.7999979432476934 EIPFNEDPNPNTHSS(ph)GPSTPLK ddPTM_PC-9_AZD4547_30min_R2 1 EIPFNEDPNPNTHSSGPSTPLK 22 0 Q86YS7-3;Q86YS7;H0YFE9 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 EIPFNEDPNPNTHS(0.103)S(0.336)GPS(0.28)T(0.28)PLK 105.17 2.3133e-05 7273800.0 23935.0 24038.0 41735.0 65635.0 44729.0 33742.0 28758.0 50299.0 31061.0 39819.0 True False 31545.832121072475 31807.81341128968 41181.566630835434 50503.86480064136 38519.15042874061 31632.10740596416 31317.406288372054 42526.44530603408 32702.821047711703 38424.94892996034 0.8209726492694401 0.8277906489678843 1.0717403087743789 1.3143508633595857 1.0024515712161903 0.8232179426867182 0.8150279222350129 1.1067404509385246 0.8510830061822924 1.0 15.229755722001816 -6.550838231344101 24.22926801530141 0.9186469191213427 1.0200560711018125 0.07555246244250624 0.15240959795545944 433.5071954919879 375666.95843317226 0.055091505791718405 0.05509285057468857 2.8129484194544995e-07 6.550838231344101 0.10140915198046985 EIPFNEDPNPNTHSS(ph)GPSTPLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EIPFNEDPNPNTHSSGPSTPLK 22 0 Q86YS7-3;Q86YS7;H0YFE9 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 EIPFNEDPNPNT(0.057)HS(0.23)S(0.61)GPS(0.051)T(0.051)PLK 95.444 9.297899999999999e-05 7708800.0 48461.0 58115.0 71987.0 79888.0 64182.0 52407.0 43857.0 39119.0 43832.0 32469.0 True False 56664.490151620834 63884.27313134514 73703.44309221773 75412.13436039056 51605.99783434205 49658.68466274919 39702.547462816605 38092.16770000661 44472.96007800292 38355.372675537415 1.4773547015425232 1.6655886431287301 1.9215937155845932 1.9661426574662768 1.345469858183798 1.2946995739770477 1.0351234962224314 0.9931377286369408 1.1594975351749672 1.0 15.227141058697583 -6.632431522699807 2.033930618189993 1.0658721963627977 1.757769647600132 0.805480054735927 0.15263405485508158 0.14382653545252205 1.2164625306489738 0.062066129696330206 0.06227698454531199 2.3311406484668172e-07 6.632431522699807 0.6918974512373344 EIPFNEDPNPNTHSS(ph)GPSTPLK ddPTM_PC-9_Lapatinib_30min_R1 1 EIPFNEDPNPNTHSSGPSTPLK 22 0 Q86YS7-3;Q86YS7;H0YFE9 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 EIPFNEDPNPNT(0.012)HS(0.276)S(0.679)GPS(0.016)T(0.016)PLK 99.42299999999999 6.1357e-05 8738600.0 66264.0 56755.0 81306.0 53228.0 49090.0 42505.0 36508.0 35648.0 43868.0 31157.0 True False 65319.06320867062 56623.587284516805 74621.33453023614 57142.56468340276 46202.62271465334 40687.16023399445 38398.2056049841 37304.336219422155 38927.12388948084 36542.445935907104 1.7874847054090381 1.549529207317721 2.042045424685494 1.5637312506017473 1.2643549584964704 1.113421917770827 1.0507836742053849 1.0208494605109728 1.0652577541677504 1.0 15.157285582247866 -6.316803652711256 1.9885270068933356 1.0503388050812874 1.773476060711254 0.8835343138612973 0.11921951619523752 0.10457129825918961 0.8129614548734967 0.041211845599697296 0.051567728703579035 4.821657385425597e-07 6.316803652711256 0.7231372556299667 EIPS(ph)ATQS(ph)PISK ddPTM_PC-9_AZD4547_30min_R2 2 EIPSATQSPISK 12 0 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 2 EIPS(0.978)AT(0.028)QS(0.926)PIS(0.068)K;EIPS(0.985)AT(0.017)QS(0.972)PIS(0.026)K 116.79 0.0037781 3864200.0 49488.0 45095.0 50003.0 69186.0 57129.0 59029.0 48103.0 52486.0 45907.0 52110.0 True False 65224.15458565431 59671.07686921161 49339.92754862019 53236.236613044515 49197.62446832083 55337.90729851994 52384.073812141345 44375.49470829449 48333.55029900201 50285.64476104957 1.2970730492885292 1.186642373837709 0.9811930976141741 1.0586766236371385 0.9783632029001744 1.1004712689173626 1.0417301808709667 0.8824684444071605 0.9611798860027819 1.0 15.617858986580677 -5.071828683582404 2.6197495958213035 1.0016718724059743 1.2972872384432188 0.7511744231130705 0.057030773048028276 0.16016157785305712 1.9823093501176805 0.01640420483589177 0.0772927085306376 8.475616863978073e-06 5.071828683582404 0.2956153660372445 EIPS(ph)ATQS(ph)PISK ddPTM_PC-9_Lapatinib_30min_R1 1 EIPSATQSPISK 12 0 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 2 EIPS(0.985)AT(0.018)QS(0.987)PIS(0.011)K 147.35 0.0016326000000000001 6516400.0 44051.0 41758.0 36982.0 34518.0 28253.0 24614.0 21650.0 20244.0 24683.0 20944.0 True False 43422.82466203596 41661.311916603874 33941.48271464827 37056.56886867243 26591.214087535172 23561.316598036432 22770.931065736422 21184.610144355433 21902.940616487085 24564.142493874213 1.7677321597065603 1.6960214233813917 1.3817491379197369 1.5085635038110357 1.08252156956696 0.9591752125649058 0.9269988183554553 0.8624200966770338 0.8916631476938071 1.0 14.584266256683234 -6.043906310469892 0.8639032041082664 0.8848247830127388 1.766243556243036 0.9342356265062242 0.0847191005922165 0.15265954788360822 0.23240109938468848 0.04018808494412986 0.0880890485259273 9.038444373490577e-07 6.043906310469892 0.8814187732302973 EIPS(ph)ATQSPIS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 EIPSATQSPISK 12 0 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 2 EIPS(0.974)AT(0.044)QS(0.392)PIS(0.591)K 118.2 0.0072161000000000005 7966200.0 54579.0 41891.0 45936.0 41564.0 36016.0 29149.0 26564.0 24222.0 30700.0 16334.0 True False 53800.69345143725 41794.00396327538 42159.319398087806 44620.755213439385 33897.6096901804 27902.365219637784 27939.353941349764 25347.442546758393 27242.24271466812 19157.3101363131 2.808363651714176 2.181621723816745 2.2006909685182734 2.329176429046778 1.7694347196440037 1.45648658507377 1.4584173739709996 1.3231211671367038 1.4220285896520437 1.0 14.225607387104294 -5.700864086704631 0.3275070017083316 1.017227574220759 3.28154193030816 0.9082909794258501 0.16163125252785615 1.1412095229422514 0.1558887458835136 0.19107813986754985 0.9805759858268005 1.9912964215387116e-06 5.700864086704631 2.264314356087401 up EIPS(ph)LSPTIPR ddPTM_PC-9_AZD4547_30min_R2 1 EIPSLSPTIPR 11 0 Q9ULD5 Q9ULD5 ZNF777 Zinc finger protein 777 1 EIPS(0.49)LS(0.49)PT(0.02)IPR 65.695 0.044052999999999995 2622700.0 22052.0 25477.0 26037.0 42555.0 33564.0 29664.0 26144.0 34805.0 30176.0 29927.0 True False 29064.077289905592 33711.94202011094 25691.73236772643 32744.602218195996 28904.217956812143 27809.105390626555 28470.765352361024 29426.68698933409 31771.041754475005 28879.264839069874 1.0063994859933447 1.1673407272647427 0.889625567371399 1.1338447291046283 1.000864049617652 0.962943674141056 0.985854920858089 1.0189555431315422 1.1001333285843529 1.0 14.817746396479253 EIPSATQS(ph)PISK ddPTM_PC-9_AZD4547_30min_R2 4 EIPSATQSPISK 12 0 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 EIPS(0.031)AT(0.191)QS(0.618)PIS(0.159)K;EIPS(0.003)AT(0.012)QS(0.968)PIS(0.018)K;EIPSAT(0.001)QS(0.992)PIS(0.006)K;EIPSAT(0.015)QS(0.979)PIS(0.006)K 214.65 9.7976e-11 1291411500.0 2496077.0 2335540.0 3217563.0 3693334.0 2950931.0 2712798.0 3018305.0 3257253.0 2514844.0 2889379.0 True False 3289777.5643730974 3090457.631026018 3174896.012301687 2841892.9077414796 2541245.1674268143 2543166.312212816 3286928.297768445 2753919.393077705 2647773.5196842165 2788222.7206685264 1.1798833500590349 1.1083969756494292 1.1386809198443262 1.019248888073075 0.9114211531916308 0.9121101744709427 1.1788614565841946 0.98769706331688 0.9496276965454773 1.0 21.41091437628745 -5.8047967960077065 4.417992776551411 0.9926933832598405 1.140300092299804 0.47101941734627795 0.07239126152552093 0.19587150462191844 8.225310557563862 0.021821836268732187 0.03465247123016146 1.567484315818292e-06 5.8047967960077065 0.14760670903996342 EIPSATQS(ph)PISK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EIPSATQSPISK 12 0 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 EIPSAT(0.05)QS(0.937)PIS(0.013)K;EIPS(0.015)AT(0.03)QS(0.771)PIS(0.184)K;EIPS(0.001)AT(0.014)QS(0.979)PIS(0.006)K;EIPSAT(0.015)QS(0.975)PIS(0.009)K 210.08 3.1086e-08 884279000.0 1375924.0 1363750.0 1216726.0 1427671.0 1613829.0 1348424.0 1641520.0 1608629.0 1478921.0 1097749.0 True False 1608840.7574622596 1499134.0872902323 1245737.3622990528 1347683.22244183 1297610.7924184073 1277710.2716752142 1486023.3420243675 1566404.1932333154 1500547.421781353 1296762.203923698 1.2406598161129967 1.1560593628918274 0.9606521215144488 1.0392678151507322 1.0006543902129021 0.985308075612601 1.1459489932140292 1.2079347998374288 1.1571492577752873 1.0 20.306482516397686 -9.815632796130743 11.446583929380257 0.9999999999949974 1.0934332192764922 0.09019271130513395 0.09294601952054027 0.0 0.0 0.0994782028347262 0.024127008102011436 1.528858189257089e-10 9.815632796130743 0.09343321928149473 EIPSATQS(ph)PISK ddPTM_PC-9_Lapatinib_30min_R1 4 EIPSATQSPISK 12 0 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 EIPS(0.005)AT(0.011)QS(0.983)PIS(0.001)K;EIPS(0.001)AT(0.058)QS(0.939)PIS(0.001)K;EIPS(0.002)AT(0.016)QS(0.971)PIS(0.011)K;EIPS(0.005)AT(0.011)QS(0.962)PIS(0.022)K 178.22 0.00019925 1153142000.0 1537879.0 1367591.0 1482357.0 1304342.0 1362652.0 1339254.0 1154030.0 1020589.0 1406180.0 840579.0 True False 1515948.5634475318 1364424.427064039 1360483.3295234935 1400267.6618373604 1282503.488436909 1281977.2283735564 1213780.0266878433 1068009.290783319 1247801.200668144 985871.9601488855 1.537672866990349 1.3839773137051032 1.3799797382593522 1.4203342000171029 1.3008824069235385 1.3003486052894266 1.2311741034855472 1.0833143997949075 1.2656828179591417 1.0 19.911040763582484 -4.942987495619336 0.13192644150676952 0.8630543427883258 2.0387879523126515 0.8432595565781682 0.05956385220819679 11.230387982702412 0.26337205014008 0.45507321258597583 2.4298389929196933 1.1402826185623769e-05 4.942987495619336 1.1757336095243258 EIPSATQS(ph)PISKK ddPTM_PC-9_AZD4547_30min_R2 1 EIPSATQSPISKK 13 1 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 EIPS(0.088)AT(0.047)QS(0.461)PIS(0.404)KK 61.126999999999995 0.025064 74573000.0 40065.0 32458.0 47656.0 59446.0 48906.0 47220.0 41960.0 49337.0 36509.0 49286.0 True False 52804.83659623017 42949.41374921544 47024.05030212276 45741.64313154457 42116.24607900892 44267.325935321795 45694.358712709174 41713.10030147324 38438.79120539927 47560.51214149085 1.110266357921833 0.9030477556978875 0.9887204360253286 0.9617567404544508 0.88552970064146 0.9307579742545257 0.9607625455497634 0.8770532196410803 0.8082081011038152 1.0 15.53747662995705 EIPSATQS(ph)PISKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EIPSATQSPISKK 13 1 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 EIPS(0.001)AT(0.239)QS(0.665)PIS(0.095)KK;EIPS(0.002)AT(0.075)QS(0.922)PIS(0.002)KK;EIPS(0.018)AT(0.066)QS(0.91)PIS(0.007)KK 105.58 0.0017819000000000003 53203600.0 255114.0 178987.0 209042.0 273693.0 300030.0 346624.0 319748.0 333127.0 343987.0 250961.0 True False 298299.7614688229 196755.64647612584 214026.35407620025 258358.86853467807 241241.2752833762 328446.42724332237 289459.1546649486 324382.7692272319 349017.15911553183 296458.24269381724 1.006211730725624 0.6636875557524489 0.7219443525381993 0.8714848546191772 0.8137445364692751 1.107901147422447 0.9763909818621662 1.0941937936340504 1.1772894419940199 1.0 18.177469384263446 -6.755288344221606 24.439444677539758 1.0711194437237355 0.804907476735253 0.6219578924447502 0.09952328616782596 72.57897398819185 288372.07637708634 0.03323345172531768 0.03241235365039479 1.7567568506129073e-07 6.755288344221606 -0.2662119669884825 EIPSATQS(ph)PISKK ddPTM_PC-9_Lapatinib_30min_R1 1 EIPSATQSPISKK 13 1 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 EIPSATQS(0.992)PIS(0.007)KK 130.27 0.00012132 9349600.0 123200.0 68798.0 70709.0 65777.0 65588.0 69387.0 57557.0 45366.0 77951.0 48158.0 True False 121443.14540788681 68638.70245793638 64895.578964633176 70614.46000563954 61730.24279096927 66419.47975899713 60537.019831436046 47473.86997672536 69171.33751957958 56482.046133498545 2.150119440093388 1.2152304520927744 1.1489594199765492 1.250210727825586 1.0929179627286574 1.1759396889059381 1.0717922592314262 0.8405125739339923 1.2246606179260782 1.0 15.785504732556236 -4.74878071686678 3.6028034055480056 1.1045116084156568 2.312266592738369 0.8868052354256667 0.11176361192555678 0.10162961764634108 2.117948191998688 0.029128172898229457 0.34902068116574986 1.783278949942029e-05 4.74878071686678 1.2077549843227124 up EIQEELDKLS(ph)PHK ddPTM_PC-9_AZD4547_30min_R2 1 EIQEELDKLSPHK 13 1 Q2KHM9 Q2KHM9 KIAA0753 Uncharacterized protein KIAA0753 1 EIQEELDKLS(1)PHK 51.463 0.041484 5935700.0 25806.0 24583.0 29434.0 27494.0 24933.0 34367.0 31252.0 31199.0 28047.0 26017.0 True False 34011.77120185487 32528.974003233816 29043.68592816605 21155.6830780656 21471.483324907553 32218.026057162322 34033.36745685383 26377.911431697576 29529.507160914654 25106.152748958473 1.354718564088472 1.2956574561024001 1.1568353868702932 0.8426493413628753 0.8552279411188676 1.283272127725698 1.3555787617943855 1.050655259507726 1.176186071047452 1.0 14.615753347416225 -5.293511795299881 3.6407906551341567 1.0880899558403465 1.3337344634554549 0.2749572609577944 0.15606685238265391 0.33314452235317554 9.422998392245452 0.04648291007344239 0.11844181817632961 5.087310024849725e-06 5.293511795299881 0.24564450761510837 EIQGHQPR ddPTM_PC-9_Lapatinib_30min_R1 2 EIQGHQPR 8 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 ; 115.49 0.0030478000000000002 4291100.0 57350.0 40840.0 50878.0 44054.0 56597.0 43112.0 43915.0 44977.0 57585.0 45210.0 False True 56532.17848329805 40745.43748920211 46695.00723475952 47293.878119835885 53268.075733983205 41268.20025898055 46188.70382225473 47066.79561661105 51099.17090306719 53024.48826146169 1.0661522692032421 0.768426793452262 0.8806309832639639 0.8919252155085705 1.0045938674847816 0.7782856867092929 0.8710825004948662 0.887642618718478 0.9636900341423225 1.0 15.694371171944336 -8.390593366158647 3.093119440580329 0.9985315474068347 0.887775328844662 0.15055702124921422 0.08491914254302728 0.42572908201146 7.500777287743844 0.07750565066055426 0.020877764960263886 4.068240639358854e-09 8.390593366158647 -0.11075621856217266 EIQNGNLHES(ph)DSESVPR ddPTM_PC-9_AZD4547_30min_R2 7 EIQNGNLHESDSESVPR 17 0 Q86UP2-2;Q86UP2-3;Q86UP2-4;Q86UP2 Q86UP2-2 KTN1 Kinectin 1 EIQNGNLHES(1)DSESVPR;EIQNGNLHES(0.991)DS(0.005)ES(0.003)VPR;EIQNGNLHES(0.988)DS(0.008)ES(0.004)VPR;EIQNGNLHES(0.578)DS(0.336)ES(0.086)VPR;EIQNGNLHES(0.977)DS(0.015)ES(0.008)VPR;EIQNGNLHES(0.997)DS(0.003)ESVPR;EIQNGNLHES(0.996)DS(0.004)ESVPR 243.16 3.8443999999999997e-47 138969000.0 95781.0 105257.7 188087.7 165225.0 148092.8 114128.3 127790.29999999999 170672.8 128821.0 125439.9 True False 126237.36563143713 139280.19309848995 185593.53420368023 127134.92895080318 127532.67098780192 106991.83935925833 139163.3891373858 144299.24043077746 135630.21506671628 121048.28728193407 1.0428678378357983 1.1506168011621005 1.5332190018633933 1.0502827574478 1.0535685704562265 0.8838773497890408 1.1496518642453797 1.1920799845328625 1.1204637266020905 1.0 16.885223141156224 EIQNGNLHES(ph)DSESVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EIQNGNLHESDSESVPR 17 0 Q86UP2-2;Q86UP2-3;Q86UP2-4;Q86UP2 Q86UP2-2 KTN1 Kinectin 1 EIQNGNLHES(0.996)DS(0.004)ESVPR;EIQNGNLHES(1)DSESVPR;EIQNGNLHES(1)DSESVPR;EIQNGNLHES(0.952)DS(0.048)ES(0.001)VPR 228.19 3.6436999999999997e-29 47240500.0 55160.4 65108.700000000004 82961.0 61671.2 99579.0 60635.3 68787.3 55362.600000000006 60503.8 53166.9 True False 64497.96625243937 71572.26144759206 84939.10487134472 58215.96260472806 80067.20978383278 57455.478125654874 62271.26896707489 53909.39041152344 61388.553613056065 62805.6381010512 1.026945481370085 1.1395833815498506 1.3524120992876765 0.9269225560778703 1.274841116254699 0.9148140177035033 0.9914917012208914 0.8583527218493644 0.9774369860598325 1.0 15.938606456107687 -6.781334185834115 24.98930846692622 0.9422581085372155 1.1433906779806384 0.41237774319545806 0.1167007171533448 233.4978517433373 293288.2142496233 0.03950831822715855 0.034888304147309805 1.6544963529338176e-07 6.781334185834115 0.20113256944342295 EIQNGNLHES(ph)DSESVPR ddPTM_PC-9_Lapatinib_30min_R1 5 EIQNGNLHESDSESVPR 17 0 Q86UP2-2;Q86UP2-3;Q86UP2-4;Q86UP2 Q86UP2-2 KTN1 Kinectin 1 EIQNGNLHES(0.999)DS(0.001)ESVPR;EIQNGNLHES(0.946)DS(0.042)ES(0.012)VPR;EIQNGNLHES(0.789)DS(0.167)ES(0.044)VPR;EIQNGNLHES(0.838)DS(0.13)ES(0.032)VPR;EIQNGNLHES(0.98)DS(0.019)ES(0.001)VPR 150.61 1.4641e-05 136358700.0 112132.2 139030.7 79613.8 51582.0 58948.0 69573.2 63381.299999999996 61404.600000000006 95670.2 36893.799999999996 True False 110533.17426547293 138708.78295617047 73068.26068215528 55375.51235250771 55480.794536227084 66597.71641905047 66662.87358691738 64257.6818845133 84894.81462413156 43270.84417210163 2.5544492228034206 3.205594566273827 1.6886257266333895 1.2797419003951493 1.282174997916904 1.5390898350439064 1.5405956334426563 1.4850110533767376 1.9619403376203717 1.0 15.401107646161455 -5.350499470768529 5.078525830344144 1.4667967424360215 2.873764446201886 0.8052111016513904 0.27827730076794416 0.07936097076155174 3.349304530038006 0.07065094706020564 0.15329564108634755 4.461701682838212e-06 5.350499470768529 1.4069677037658646 EIQTAVR ddPTM_PC-9_Lapatinib_30min_R1 1 EIQTAVR 7 0 Q16778;P33778;P23527;P06899;Q96A08;U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 Q16778;U3KQK0 HIST2H2BE;HIST1H2BB;HIST1H2BO;HIST1H2BJ;HIST1H2BA;HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B type 2-E;Histone H2B type 1-B;Histone H2B type 1-O;Histone H2B type 1-J;Histone H2B type 1-A;Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 0 122.18 0.024419999999999997 172950000.0 182000.0 165850.0 173690.0 145500.0 149390.0 149860.0 165650.0 136700.0 170360.0 116200.0 False True 179404.64662528722 165465.98451479382 159409.87866278904 156200.55537377147 140603.1739120404 143450.83714072226 174226.54646832493 143051.58104788492 151172.26282966963 136285.01517323265 1.3163930487680173 1.2141172256133155 1.1696801622699475 1.1461315477363676 1.0316847654404184 1.0525796761909672 1.278398408268617 1.0496501091191226 1.1092361301608524 1.0 17.056267417917248 -4.835297327776916 0.9410085703528437 1.0979571823496401 1.4170947930519928 0.49162590512753956 0.07294319020016331 1.787566524955616 1.322023956898935 0.02558098247727464 0.5754579210579108 1.4611764776429367e-05 4.835297327776916 0.3191376107023527 EIS(ph)DDEAEEEK ddPTM_PC-9_AZD4547_30min_R2 1 EISDDEAEEEK 11 0 P08238;Q58FF7 P08238 HSP90AB1;HSP90AB3P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 1 EIS(1)DDEAEEEK 152.4 9.4607e-08 0.0 9400.9 7998.5 9907.4 6420.3 8435.5 10294.0 8887.6 9624.9 10362.0 7115.4 True False 12390.19064913267 10583.858705807486 9776.02140261984 4940.199027646194 7264.376432328945 9650.314552693824 9678.57918243742 8137.592863199015 10909.714165557732 6866.2920117592 1.80449515224713 1.5414227486511771 1.4237701201576398 0.7194857164806882 1.0579766225916385 1.4054622984526017 1.4095787312660022 1.1851510027919854 1.5888800165902899 1.0 12.745315498636328 -5.195203306621059 2.4180499681019585 1.2123001223042693 1.7527630279570827 0.3935360615424246 0.23769442736266652 0.34890426040006706 3.776260261562183 0.06823737941174776 0.26441358494822803 6.3796476532304055e-06 5.195203306621059 0.5404629056528134 EIS(ph)DDEAEEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EISDDEAEEEK 11 0 P08238;Q58FF7 P08238 HSP90AB1;HSP90AB3P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 1 EIS(1)DDEAEEEK 136.27 7.9854e-05 8242800.0 14272.0 41606.0 17893.0 12359.0 17402.0 12189.0 15592.0 3982.0 11963.0 12227.0 True False 16687.967715150997 45736.368715525176 18319.636979580384 11666.565298418614 13992.20302130225 11549.787382491846 14115.012883695557 3877.4767192777495 12137.936243227528 14443.658311121259 1.1553837231320874 3.16653632551729 1.268351589671345 0.8077292502437314 0.9687437019005497 0.7996441852684092 0.9772463858984637 0.2684553065266151 0.8403643995013105 1.0 13.818148575989788 -5.486240637684886 7.601878191864698 0.8090601612179641 2.180617897312422 0.5433891540396903 0.4906570494679456 0.16427090646401277 29.28341223434211 0.12016500140636946 0.2448905738625589 3.2640692365425403e-06 5.486240637684886 1.371557736094458 EIS(ph)DDEAEEEK ddPTM_PC-9_Lapatinib_30min_R1 1 EISDDEAEEEK 11 0 P08238;Q58FF7 P08238 HSP90AB1;HSP90AB3P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 1 EIS(1)DDEAEEEK 176.18 1.4874e-25 0.0 10494.0 15457.0 7635.3 7480.5 9365.4 7776.0 10119.0 11281.0 6484.5 10467.0 True False 10344.353635636093 15421.210266175243 7007.555107110329 8030.640924216468 8814.54558508484 7443.43860674134 10642.912307352735 11805.156443315227 5754.1473251878015 12276.207003599182 0.8426343440285178 1.2561868875014894 0.5708241238564835 0.6541630425311349 0.7180186504268428 0.6063304899110161 0.8669544513409075 0.96162898196928 0.46872354983104964 1.0 13.583577257653523 -5.266968688813267 24.994209713839197 0.7266794824601369 1.0494106166601003 0.3193948163696875 0.18594220646375595 454.9200839298176 2056389.0176693113 0.04660537374505303 0.10153213397192336 5.407933109379701e-06 5.266968688813267 0.32273113419996335 EIS(ph)DDEAEEEKGEK ddPTM_PC-9_Lapatinib_30min_R1 3 EISDDEAEEEKGEK 14 1 P08238;Q58FF7 P08238 HSP90AB1;HSP90AB3P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 1 EIS(1)DDEAEEEKGEK;EIS(1)DDEAEEEKGEK;EIS(1)DDEAEEEKGEK 114.01 8.4757e-05 56990000.0 134997.1 142162.1 76338.1 97354.9 109965.7 77336.2 115639.3 131995.7 82993.7 107353.6 True False 133072.01659856376 141832.93239186343 70061.87609158772 104514.70411242612 103497.73372688449 74028.71100548745 121626.53712655957 138128.70209599385 73646.07554359444 125909.52672031969 1.0568860042985784 1.126467044125375 0.5564461873263551 0.8300778093192467 0.8220008161636723 0.5879516263286887 0.9659835938921935 1.0970472663503563 0.5849126548397168 1.0 16.94202792057702 -5.226229380334771 24.980800427663944 0.8084399973966248 1.0916766778039368 0.29695031393571314 0.17605759024702902 753.1942787940554 534374.2868257049 0.044381667982743525 0.11741287062731441 5.939783555471959e-06 5.226229380334771 0.2832366804073121 EIS(ph)PGSGPGEIR ddPTM_PC-9_AZD4547_30min_R2 2 EISPGSGPGEIR 12 0 E9PK52;E9PHY5;O43491-4;E9PMG5;O43491;E9PMV8;Q6R5J7 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 EIS(0.561)PGS(0.439)GPGEIR;EIS(0.958)PGS(0.042)GPGEIR 135.04 5.9204e-05 67234900.0 31254.0 33989.0 54473.0 58800.0 52448.0 55761.0 47341.0 66011.0 40161.0 48018.0 True False 41192.12187641526 44975.27955887865 53750.6524279741 45244.56845094407 45166.5005183793 52274.25585513509 51554.25728833092 55810.51673187565 42283.8284696935 46336.90443554167 0.8889700850370095 0.9706146775825918 1.1599966178738923 0.9764262201391306 0.974741430584978 1.1281343993933117 1.1125960595845803 1.2044506945756925 0.9125302819594623 1.0 15.499874046871199 -6.755335635661781 24.99153564262847 1.0868863178728265 1.0010713628455614 0.12583004700841582 0.09704908082914339 289.22193588110815 1184208.8261290705 0.03258266709900128 0.03177015161026339 1.7565655632681342e-07 6.755335635661781 -0.0858149550272651 EIS(ph)PGSGPGEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EISPGSGPGEIR 12 0 E9PK52;E9PHY5;O43491-4;E9PMG5;O43491;E9PMV8;Q6R5J7 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 EIS(0.934)PGS(0.066)GPGEIR;EIS(1)PGSGPGEIR;EIS(0.592)PGS(0.408)GPGEIR 193.15 1.8548e-05 102738000.0 85483.0 88939.0 121086.0 99356.0 110721.0 91018.0 89844.0 87107.0 75781.0 60658.0 True False 99953.58353379018 97768.27614262573 123973.1494612121 93789.40543649814 89026.0148673491 86244.8558519683 81333.32590576845 84820.53354749565 76889.15376143304 71654.81523153628 1.3949318438797567 1.3644341392369757 1.730144011405528 1.3089058304517143 1.24242892232269 1.2036156338312731 1.135071322743046 1.1837380819895682 1.0730493619023813 1.0 16.12877603696409 -6.3006056653021485 1.7908606093557191 1.1306302446698493 1.4816336536402877 0.6718551505106609 0.11164781594576605 0.22173556873684952 1.403321097562688 0.040166466153697365 0.05163306722908101 5.004887671205583e-07 6.3006056653021485 0.35100340897043836 EIS(ph)PGSGPGEIR ddPTM_PC-9_Lapatinib_30min_R1 3 EISPGSGPGEIR 12 0 E9PK52;E9PHY5;O43491-4;E9PMG5;O43491;E9PMV8;Q6R5J7 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 EIS(0.844)PGS(0.156)GPGEIR;EIS(0.934)PGS(0.066)GPGEIR;EIS(0.996)PGS(0.004)GPGEIR 148.78 0.00015331 61967000.0 67683.0 76583.0 89423.0 70861.0 76846.0 73994.0 66922.0 68284.0 81376.0 64613.0 True False 66717.82800845797 76405.67676874535 82070.98612276213 76072.35432536651 72326.06936504896 70829.44910843861 70386.89370813909 71456.72392299786 72210.57795273076 75781.27095858924 0.8803999611581601 1.0082395795459451 1.0829982802427516 1.0038410990353583 0.9544055998291664 0.9346563895338129 0.9288164848357068 0.9429338280964628 0.9528815898613037 1.0 16.209553715625653 -6.301735575986402 5.329578174069726 0.9469464109646074 1.0013304588526386 0.13285313210637217 0.04971861415610462 0.3372823888693849 24.967586431539672 0.016070660710240558 0.018661907351384534 4.991883301556263e-07 6.301735575986402 0.054384047888031195 EIS(ph)PYENK ddPTM_PC-9_AZD4547_30min_R2 1 EISPYENK 8 0 Q8NG31-2;Q8NG31;Q8NG31-4;H0YCZ2 Q8NG31-2 CASC5 Protein CASC5 1 EIS(0.996)PY(0.004)ENK 75.652 0.026068 6295100.0 41675.0 42063.0 55307.0 58199.0 57749.0 53478.0 34668.0 47384.0 36038.0 50328.0 True False 54926.78310614979 55659.042163203136 54573.593043048175 44782.11971558662 49731.54817029987 50134.01220603854 37753.38483918496 40061.89157599788 37942.895106964854 48566.03203865095 1.1309711911905154 1.1460487881510941 1.1236988230707452 0.922087266259411 1.0239985867225339 1.0322855317094821 0.7773619390840739 0.8248953001578324 0.7812640546126614 1.0 15.567659999079513 -6.332245481628249 0.7142992480839165 0.8380008579590649 1.155562688374662 0.6038479950117952 0.08535665971754536 0.5077570848937446 0.5648797840915074 0.05456141091165191 0.09016932053250104 4.653229989141152e-07 6.332245481628249 0.31756183041559705 EIS(ph)QDSLAAR ddPTM_PC-9_AZD4547_30min_R2 1 EISQDSLAAR 10 0 A0A087X0K9;G5E9E7;Q07157-2;H0YKB1;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 EIS(0.986)QDS(0.014)LAAR 98.40700000000001 0.0047712 2512500.0 10975.0 8847.7 14715.0 19135.0 19552.0 16668.0 12835.0 19661.0 13451.0 11877.0 True False 14464.821705818702 11707.545998796393 14519.869485389798 14723.721382802976 16837.5422920865 15625.747325072922 13977.290135310357 16622.844214834007 14161.992399239241 11461.18984507745 1.2620698113670374 1.021494814853342 1.2668727838607474 1.284659060867644 1.4690919982726032 1.363361704699808 1.219532206013808 1.4503593814889537 1.235647658809332 1.0 13.484469205013019 -5.463332132450777 6.802475743760015 1.3126637557539105 1.1407742883608842 0.13682459136715452 0.13715775464897695 0.3583208637168874 33.8763438467201 0.03389674524850465 0.07047733731415937 3.4408668527108423e-06 5.463332132450777 -0.17188946739302624 EIS(ph)QDSLAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EISQDSLAAR 10 0 A0A087X0K9;G5E9E7;Q07157-2;H0YKB1;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 EIS(0.919)QDS(0.081)LAAR 90.79299999999999 0.008483599999999999 3137900.0 11165.0 13279.0 18186.0 13925.0 20919.0 14224.0 11826.0 14181.0 12074.0 14437.0 True False 13055.013981198215 14597.2513621463 18619.62321078908 13144.827395459122 16820.07211829799 13478.068400079077 10705.755667174431 13808.7637760115 12250.559408236151 17054.313816770886 0.7654962915224514 0.8559272169479867 1.091783780387511 0.7707626080231238 0.9862649590602381 0.7903025911734427 0.627744732634543 0.8096933083541729 0.7183261396415249 1.0 14.057849088587135 -6.931087297185264 9.018550625997175 0.7640096820097869 0.8956872824306109 0.13556084052774187 0.1261880933812898 0.496307243220917 59.830259381936955 0.04284052609621084 0.03777401192958216 1.1719597671779616e-07 6.931087297185264 0.131677600420824 EIS(ph)TPTHWSK ddPTM_PC-9_AZD4547_30min_R2 1 EISTPTHWSK 10 0 F5H1H2;F5H2E6;A0A0C4DGG8;Q8IX12-2;Q8IX12 F5H1H2 CCAR1 Cell division cycle and apoptosis regulator protein 1 1 EIS(0.559)T(0.436)PT(0.005)HWSK 83.617 0.007536399999999999 3968000.0 9690.0 10293.0 50629.0 77960.0 65629.0 59425.0 27170.0 78012.0 35797.0 55475.0 True False 12771.218435479108 13620.01095941446 49957.62637959907 59987.52646999322 56517.54618900085 55709.145355919034 29588.077364735676 65957.0379374209 37689.15633897606 53532.83713527587 0.23856793547494265 0.25442348450535324 0.9332146221459858 1.1205743928424072 1.0557547332337853 1.0406537059701075 0.5527089343306706 1.2320856032858758 0.7040380886919313 1.0 15.708136494233502 -5.265028296467804 5.9551181896279735 0.9629537790027188 0.24021358373541898 0.6972663451788241 0.18674948961224627 0.07349408979431347 11.834439026298378 0.047071092537022866 0.11174273851502725 5.432149371566026e-06 5.265028296467804 -0.7227401952672998 EIS(ph)TPTHWSK ddPTM_PC-9_Lapatinib_30min_R1 2 EISTPTHWSK 10 0 F5H1H2;F5H2E6;A0A0C4DGG8;Q8IX12-2;Q8IX12 F5H1H2 CCAR1 Cell division cycle and apoptosis regulator protein 1 1 EIS(0.497)T(0.497)PT(0.006)HWS(0.001)K;EIS(0.498)T(0.498)PT(0.003)HWSK 74.69800000000001 0.014463 5171600.0 47224.0 47003.0 99940.0 43982.0 69440.0 91441.0 57338.0 69635.0 107891.0 48790.0 True False 46550.577100179056 46894.167441355705 91723.31897955609 47216.58299965097 65355.67572429266 87530.28158938215 60306.68108301134 72870.4963150657 95739.1794374025 57223.286491411534 0.813490100872932 0.8194944805974034 1.6029019758122869 0.8251288224547809 1.1421167802744376 1.5296269570696417 1.0538835635045636 1.2734412995660884 1.6730807562367411 1.0 15.804314737551383 -5.216133249385077 21.1825823285015 1.254454745367842 0.8164885636128478 0.3202003663075539 0.2597456605204659 90.70749134648524 42407.39685629081 0.06443696839613282 0.17047726492623683 6.0794844310604036e-06 5.216133249385077 -0.43796618175499424 EISEGDEVEVYSR ddPTM_PC-9_Lapatinib_30min_R1 1 EISEGDEVEVYSR 13 0 B4DXZ6;P51114;P51114-2;C9JAJ4 B4DXZ6 FXR1 Fragile X mental retardation syndrome-related protein 1 0 88.596 0.041248 0.0 7335.3 5630.2 5336.0 4454.7 7874.0 4261.7 5302.9 7088.5 5916.5 3315.7 False True 7230.697276870725 5617.16361781846 4897.294677555656 4782.313498443569 7410.866800879618 4079.437025507918 5577.458214711024 7417.857587841505 5250.121466492964 3888.814327107462 1.859357806431707 1.4444411960384236 1.2593284907994853 1.229761334992998 1.9056880008956079 1.049018205130468 1.4342310394797357 1.9074856662953563 1.3500571189260289 1.0 11.925114639064974 -11.53434970889888 1.6141851000245329 0.49206584487887833 1.4867089936396733 0.20966850005880977 0.28704927236712274 291466.4686678829 75913.32243680792 549225.1157080238 0.07794672669970737 2.921798697232491e-12 11.53434970889888 0.994643148760795 EISPGS(ph)GPGEIR ddPTM_PC-9_AZD4547_30min_R2 2 EISPGSGPGEIR 12 0 E9PK52;E9PHY5;O43491-4;E9PMG5;O43491;E9PMV8;Q6R5J7 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 EIS(0.314)PGS(0.686)GPGEIR;EIS(0.171)PGS(0.829)GPGEIR 183.06 0.00055864 67545800.0 42914.0 42308.0 53902.0 63373.0 56863.0 54532.0 53120.0 73261.0 49436.0 61041.0 True False 56559.759333348826 55983.23362196706 53187.22426105888 48763.33395308976 48968.553976826646 51122.10541941907 57847.5770929245 61940.19582030188 52049.08603440571 58903.97316943443 0.9602027892186052 0.9504152370322116 0.9029479914380037 0.8278445634358889 0.8313285393494759 0.8678889159542568 0.9820657925150268 1.0515452946125365 0.883626065166929 1.0 15.846077329029914 -7.270028556033235 23.205450749414062 0.9836047530975321 0.8879282013815116 0.3765436806688697 0.056081911020093494 268.7625493064736 726111.6490000082 0.0248285830754768 0.01707143359163356 5.369964862424466e-08 7.270028556033235 -0.09567655171602052 EISPGS(ph)GPGEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EISPGSGPGEIR 12 0 E9PK52;E9PHY5;O43491-4;E9PMG5;O43491;E9PMV8;Q6R5J7 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 EIS(0.376)PGS(0.624)GPGEIR 143.55 8.5614e-05 8979500.0 27001.0 29298.0 39553.0 36195.0 40331.0 34901.0 36090.0 28680.0 31416.0 24756.0 True False 31571.73600594114 32206.51181626345 40496.09352558783 34167.11149577328 32428.430068505968 33070.73012030091 32671.293931027005 27927.180388971854 31875.39956676719 29244.066831611817 1.079594578542448 1.1013007185939452 1.384762719862648 1.1683433666223133 1.1088892066630065 1.1308526379290245 1.1171939292557789 0.9549691070594718 1.0899783450197493 1.0 14.835856333446438 -7.254440847628397 1.1271424151312275 1.0150973708709705 1.1826402714693025 0.3556896029291037 0.08674736175568945 0.579254049850767 1.4341995630828577 0.062318304825419564 0.03565009529257851 5.56620442675045e-08 7.254440847628397 0.167542900598332 EISPGS(ph)GPGEIR ddPTM_PC-9_Lapatinib_30min_R1 1 EISPGSGPGEIR 12 0 E9PK52;E9PHY5;O43491-4;E9PMG5;O43491;E9PMV8;Q6R5J7 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 EIS(0.333)PGS(0.667)GPGEIR 156.52 0.00037460000000000005 47124000.0 33441.0 43851.0 38255.0 31025.0 41911.0 32853.0 31970.0 31873.0 39613.0 30394.0 True False 32964.12520767167 43749.46570369744 35109.82156857039 33306.68199636604 39445.87738019631 31447.953774083497 33625.2501695886 33353.935938107126 35151.36679661719 35647.56240254071 0.9247231223115053 1.2272779049986118 0.9849150741950313 0.9343326654501395 1.1065518852246932 0.882190861158072 0.9432692701364632 0.9356582523502334 0.9860805179237683 1.0 15.121515807410741 -5.492724154817147 24.84916492458598 0.9673526102774725 1.0835245365788932 0.18579329431504543 0.08752332529004346 862.7643513729021 710967.4558578706 0.02156989797050443 0.044799137470467154 3.215702366018219e-06 5.492724154817147 0.1161719263014207 EISS(ph)SPTSK ddPTM_PC-9_AZD4547_30min_R2 2 EISSSPTSK 9 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 EIS(0.002)S(0.499)S(0.499)PT(0.001)SK;EISS(0.653)S(0.346)PTSK 141.91 0.0006911 78028000.0 301837.0 226034.0 345090.0 409330.0 369620.0 334703.0 273037.0 350180.0 304169.0 361972.0 True False 397814.887400382 299095.0701642169 340513.88112219976 314965.29258545843 318304.6431056163 313773.9684991529 297336.7640572447 296067.72733587184 320246.75236667943 349299.4704557018 1.1388934740765173 0.856271181213108 0.9748479740835558 0.9017056114472477 0.9112657476701893 0.8982950019643553 0.8512373742489053 0.8476042833664106 0.9168257597095131 1.0 18.41410493001954 -4.754675041395883 24.99995900621517 0.9018473336772844 1.138893876804448 0.6792738721281982 0.04782218773482626 131.35180133872848 485412.72882771405 0.011605052081863668 0.11077444166170583 1.7592394634552776e-05 4.754675041395883 0.23704654312716367 EISS(ph)SPTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EISSSPTSK 9 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 EIS(0.017)S(0.491)S(0.491)PT(0.001)S(0.001)K;EISS(0.616)S(0.383)PT(0.001)SK;EIS(0.003)S(0.498)S(0.498)PTSK 114.89 0.0020117 208271800.0 319735.0 312940.0 306794.0 331122.0 348459.0 321125.0 323964.0 302888.0 277866.0 246352.0 True False 373859.8204458952 344006.6150515891 314109.13248272345 312570.30785200757 280180.9603838621 304284.63969174604 293275.78462375293 294937.51093636337 281929.264579174 291013.6674786406 1.284681313029173 1.182097796409641 1.079362131697055 1.0740743229008278 0.9627759507358065 1.0456025736800814 1.0077732333491805 1.013483364859524 0.9687835867704275 1.0 18.150727385441918 -4.644167248849728 0.7503280739251171 0.9993067667419194 1.5172313482073037 0.9271516851692617 0.02594445387624228 0.7744924330039835 0.2884986801989848 0.010065667209494856 0.3547860622506576 2.2689908845376462e-05 4.644167248849728 0.5179245814653842 EISS(ph)SPTSK ddPTM_PC-9_Lapatinib_30min_R1 3 EISSSPTSK 9 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 EISS(0.499)S(0.499)PT(0.002)SK;EIS(0.005)S(0.49)S(0.49)PT(0.012)S(0.002)K;EIS(0.001)S(0.498)S(0.498)PT(0.002)SK 130.98 0.0012483 228235200.0 442440.0 369416.0 391739.0 376938.0 435396.0 371989.0 371983.0 364376.0 427650.0 312722.0 True False 436130.7244664414 368560.63994885125 359531.7315762704 404659.2779483066 409786.86330147064 356079.89761871233 391242.45961320214 381306.2391799876 379483.55364585784 366775.58102412825 1.1890942228178234 1.0048668968630319 0.9802499135094239 1.1032884927028066 1.11726866373504 0.9708386164216524 1.0667080357987746 1.0396172998084718 1.0346478153923055 1.0 18.48453806563777 -4.753548706175454 24.959844535714662 1.0384508808299748 1.189094501839492 0.49311250252967764 0.04668573841546291 255.10122952929083 806872.793890576 0.011894116644638977 0.1253511854873804 1.7638079421227532e-05 4.753548706175454 0.15064362100951723 EISSS(ph)PTSK ddPTM_PC-9_AZD4547_30min_R2 2 EISSSPTSK 9 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 EISS(0.382)S(0.618)PTSK;EISS(0.273)S(0.683)PT(0.041)S(0.003)K 145.99 0.00046257 358410000.0 640290.0 652840.0 763180.0 851860.0 820490.0 717980.0 700240.0 757600.0 701940.0 746420.0 True False 843888.901140653 863857.7630179853 753059.7345470473 655476.8381058024 706579.1261883191 673084.5970995831 762560.0034553728 640530.327916091 739043.115361088 720288.062992567 1.1715991760776432 1.1993226146618785 1.0454980073088043 0.9100204095879437 0.9809674246893783 0.9344658500977115 1.0586875482667024 0.889269669769192 1.0260382662605843 1.0 19.45821446979373 -5.41536011521322 3.5287196797076357 0.9693356787255231 1.185177943885033 0.7447441618673721 0.049430515833620146 0.10476121474588002 2.3703081998453714 0.0124771033246166 0.028411626523073275 3.842730122877103e-06 5.41536011521322 0.21584226515950988 EISSS(ph)PTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EISSSPTSK 9 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 EISS(0.13)S(0.867)PT(0.003)SK;EISS(0.347)S(0.652)PTSK;EISS(0.039)S(0.96)PTSK 192.44 0.00047284 202166000.0 620418.0 582358.0 589371.0 694843.0 733647.0 598028.0 660431.0 631415.0 602601.0 469295.0 True False 725442.5135859419 640170.6535700575 603423.8398419635 655913.1994213995 589894.1368790552 566666.3589118741 597870.1945736231 614841.0252894941 611412.8996159106 554374.4685628243 1.3085785055480623 1.1547621506265495 1.088476966492155 1.1831591038487161 1.0640716164442297 1.0221725404867863 1.0784591074757797 1.109071683772568 1.1028879111279317 1.0 19.08050129084777 -1.5228787461226672 0.7044932217829162 1.073787228791421 30.660287769562043 0.7104668894010056 0.045086192976204156 167.2385947709888 0.8718606453004287 0.01807985581189714 7799.770256057716 0.029999999941813932 1.5228787461226672 29.586500540770622 EISSS(ph)PTSK ddPTM_PC-9_Lapatinib_30min_R1 2 EISSSPTSK 9 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 EISS(0.03)S(0.96)PT(0.003)S(0.006)K;EIS(0.001)S(0.049)S(0.942)PT(0.008)S(0.001)K 136.49 0.00099881 226147000.0 779220.0 592731.0 672622.0 642161.0 716720.0 624280.0 583853.0 606859.0 724030.0 538187.0 True False 768108.1799085523 591358.5677867853 617321.615556005 689387.6621262974 674563.9387257358 597580.9996677579 614082.0515253309 635055.8845876995 642482.1170260959 631211.9058608986 1.216878472627894 0.9368621889034904 0.9779942517308053 1.0921651757915656 1.0686806323871698 0.9467201016316825 0.972861959388734 1.006089838754797 1.01785487735664 1.0 19.26776489202596 -6.748426159129105 24.989196448201895 0.9880957532011285 1.0491535470824203 0.18618705041568928 0.07164570968741395 466.2875053299382 895406.6905689304 0.023809797030415854 0.023665473137267166 1.7847354121844452e-07 6.748426159129105 0.06105779388129173 EITALAPS(ph)TMK ddPTM_PC-9_AZD4547_30min_R2 6 EITALAPSTMK 11 0 P60709;P63267-2;A0A2R8YFE2;P63261;P68133;P68032;P63267;P62736;A6NL76 P60709;P63261;P68133 ACTB;ACTG2;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 1 EIT(0.001)ALAPS(0.816)T(0.183)MK;EITALAPS(0.957)T(0.043)MK;EITALAPS(0.81)T(0.19)MK;EITALAPS(0.995)T(0.005)MK;EITALAPS(0.968)T(0.032)MK;EITALAPS(0.948)T(0.052)MK 166.62 0.00013395 205088400.0 893962.0 1199544.0 1144041.0 1672564.0 1539585.0 1442869.0 920719.0 1376504.0 1029585.0 1060654.0 True False 1178223.3204352704 1587273.1396385743 1128870.2688368896 1286980.2106562047 1325840.1979215418 1352646.173336971 1002661.2073309575 1163796.935715164 1084006.7611605644 1023520.8262979498 1.151147382801067 1.5507971101865148 1.1029284796480265 1.257405005925655 1.295371978621162 1.3215619444007405 0.9796197415518735 1.137052520879902 1.0590959493041199 1.0 19.9651090275146 -7.2556042438178725 24.99522424942366 1.05536309379926 1.2838244729436417 0.4882966428092427 0.11804475765051624 414.42921882095675 1775241.9594940944 0.044313566596772956 0.03340431868311866 5.5513135280292753e-08 7.2556042438178725 0.2284613791443817 EITALAPS(ph)TMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EITALAPSTMK 11 0 P60709;P63267-2;A0A2R8YFE2;P63261;P68133;P68032;P63267;P62736;A6NL76 P60709;P63261;P68133 ACTB;ACTG2;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 1 EITALAPS(0.979)T(0.021)MK;EITALAPS(0.968)T(0.032)MK;EITALAPS(0.96)T(0.04)MK 118.24 0.00095382 119484000.0 633320.0 706150.0 598470.0 721590.0 821590.0 669640.0 815100.0 588720.0 603480.0 532836.0 True False 740528.5673598247 776251.9052172293 612739.7945101137 681161.6517263447 660605.3373331635 634522.8995661527 737887.827187037 573266.7238004013 612304.7533280072 629434.9488725461 1.1764973786191428 1.2332519930894592 0.9734759653998606 1.082179584953858 1.0495212229896835 1.0080833622326186 1.1723019646569568 0.9107640508796752 0.9727848039337142 1.0 19.263697759786368 -1.5228787452820385 0.3614127736113477 0.9965298553069587 3.7868565480349297 0.40576553170699803 0.07724688592665792 64.15842398742284 0.89432094610719 0.06326753523383591 123.31417923142102 0.029999999999882506 1.5228787452820385 2.790326692727971 EITALAPS(ph)TMK ddPTM_PC-9_Lapatinib_30min_R1 3 EITALAPSTMK 11 0 P60709;P63267-2;A0A2R8YFE2;P63261;P68133;P68032;P63267;P62736;A6NL76 P60709;P63261;P68133 ACTB;ACTG2;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 1 EIT(0.012)ALAPS(0.986)T(0.002)MK;EITALAPS(0.945)T(0.055)MK;EITALAPS(0.77)T(0.23)MK 148.13 0.00027484 184235700.0 1007000.0 1027375.0 920812.0 660711.0 983358.0 933844.0 1028547.0 960871.0 844645.0 679151.0 True False 992639.9953388175 1024996.1763092336 845106.3917971103 709301.8910072848 925518.815796213 893905.669016688 1081800.1309408776 1005516.5744920465 749512.1855938395 796541.3454381765 1.2461876599673145 1.286808503010455 1.0609699002281145 0.8904771799599411 1.1619218777489648 1.1222338603465103 1.3581217561855254 1.262353272997917 0.9409582941128231 1.0 19.603389722955157 -8.273427208274503 24.555139303665655 0.9704790966424183 1.168258504166365 0.29454673773788165 0.12554028926282484 974.1344770012387 1995331.1247783045 0.12998071049001939 0.0346792092186878 5.3281052075354775e-09 8.273427208274503 0.19777940752394663 EITALAPST(ph)MK ddPTM_PC-9_Lapatinib_30min_R1 1 EITALAPSTMK 11 0 P60709;P63267-2;A0A2R8YFE2;P63261;P68133;P68032;P63267;P62736;A6NL76 P60709;P63261;P68133 ACTB;ACTG2;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 1 EITALAPS(0.125)T(0.875)MK 80.014 0.039252999999999996 0.0 21896.0 23748.0 23228.0 18025.0 27109.0 21822.0 21711.0 22045.0 21856.0 15597.0 True False 21583.759024765382 23693.012965072758 21318.28350267293 19350.618629637316 25514.501918344642 20888.72392956657 22835.089347261135 23069.291179229167 19394.347126116816 18292.920668303865 1.1798968254513644 1.2952012089641667 1.1653843521888285 1.0578200704257208 1.394774644300164 1.141902067380659 1.2483019940510365 1.261104861139059 1.0602105304989045 1.0 14.158997815340475 -8.402483664053428 4.193128664915031 1.0030111088746254 1.2175353567610152 0.43201854832578 0.08723524828950868 0.19870005366983823 5.4306229734823335 0.08123779762138066 0.021336727006013162 3.958369539259268e-09 8.402483664053428 0.2145242478863898 EITALAPSTMK ddPTM_PC-9_Lapatinib_30min_R1 3 EITALAPSTMK 11 0 P60709;P63267-2;A0A2R8YFE2;P63261;P68133;P68032;P63267;P62736;A6NL76 P60709;P63261;P68133 ACTB;ACTG2;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 0 ;; 164.97 0.00025513 334840000.0 2052460.0 2011150.0 2136020.0 2135740.0 2167970.0 1906250.0 2205320.0 1774960.0 1777510.0 1944720.0 False True 2023191.5440249352 2006493.305739692 1960404.680875639 2292809.4442197797 2040454.2669930158 1824724.1311857856 2319500.67888637 1857431.1214100495 1577308.1057898928 2280862.2608234826 0.8870292515140664 0.879708231489291 0.8595015641882094 1.0052380117824316 0.8945977589441679 0.8000150480489722 1.016940268040972 0.8143547961284793 0.691540270923866 1.0 21.121147895576634 -7.906300155512638 24.41635723833308 0.8145984309144054 0.9035529821873428 0.09641490039112588 0.0928959079829165 23.60261814721938 6133.057280230297 0.04829772955765191 0.023201477807239197 1.2407944564309972e-08 7.906300155512638 0.08895455127293739 EIVHLQAGQCGNQIGAK ddPTM_PC-9_AZD4547_30min_R2 1 EIVHLQAGQCGNQIGAK 17 0 P04350;M0R2D3;M0R042;M0QYM7;M0R0X0;M0QY85;M0QY37;M0QX14;M0QZL7;M0R278;M0R2T4;P68371 P04350;P68371 TUBB4A;TUBB4B Tubulin beta-4A chain;Tubulin beta-4B chain 0 161.08 2.5294000000000002e-05 30279000.0 148040.0 145790.0 218650.0 278800.0 295690.0 219880.0 204190.0 236910.0 202000.0 254160.0 False True 195113.6405767108 192913.76642116337 215750.55813662772 214526.96741706145 254638.5474809256 206130.86884071538 222362.514431556 200301.00315021203 212677.30760882652 245261.93576028282 0.795531683185496 0.786562194509122 0.8796740410118131 0.8746851269523473 1.0382310108234953 0.8404519364235392 0.9066327954326 0.8166819793267257 0.8671435579661074 1.0 17.903963821862618 -5.346168176530889 2.8698648844012955 0.9006568009703754 0.7879611868432652 0.3287661656627783 0.06439400675629077 0.32981950255492315 5.206625028109212 0.01774940935992885 0.04711865065906502 4.506421637291454e-06 5.346168176530889 -0.11269561412711016 EIVHLQAGQCGNQIGAK ddPTM_PC-9_Lapatinib_30min_R1 2 EIVHLQAGQCGNQIGAK 17 0 P04350;M0R2D3;M0R042;M0QYM7;M0R0X0;M0QY85;M0QY37;M0QX14;M0QZL7;M0R278;M0R2T4;P68371 P04350;P68371 TUBB4A;TUBB4B Tubulin beta-4A chain;Tubulin beta-4B chain 0 ; 281.65 1.0929999999999998e-83 92626000.0 290230.0 295690.0 305920.0 297510.0 300750.0 299890.0 314640.0 258580.0 286510.0 265460.0 False True 286091.26697833673 295005.3479721389 280768.4384853498 319389.87786426576 283060.47629725013 287064.40377773397 330930.51965465664 270594.570792701 254240.22671594666 311344.4072967838 0.9188900146377932 0.9475209480507225 0.9017937432154098 1.0258410633977206 0.9091554871818446 0.9220156105264311 1.0629081875211033 0.8691165296403133 0.8165883849443824 1.0 18.248151838644247 EIVLADVIDNDSWR ddPTM_PC-9_AZD4547_30min_R2 2 EIVLADVIDNDSWR 14 0 E9PBS1;P22234;P22234-2;D6RF62 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 0 ; 147.87 6.9576e-08 0.0 7619.3 6342.1 8397.5 16730.9 9272.8 10956.8 7855.6 9321.3 5514.4 9854.3 False True 10042.07890871475 8392.059798474927 8286.143663170975 12873.849494828233 7985.431780178986 10271.669563916434 8554.733181686328 7880.907267165063 5805.879926129274 9509.30395641548 1.0560267033992357 0.8825104168442527 0.871372258279819 1.3538161734900536 0.8397493461960053 1.0801704952323687 0.8996171771241839 0.8287575308651466 0.6105473074306684 1.0 13.215124030019462 -7.597208272561879 2.80371941897995 0.7867398107493451 1.0088987785682568 0.22985961656969023 0.1638302884867127 0.37763184387118476 5.983504747383732 0.08816140879574215 0.04606742285747712 2.5280853237042656e-08 7.597208272561879 0.22215896781891176 EIVLADVIDNDSWR ddPTM_PC-9_Lapatinib_30min_R1 2 EIVLADVIDNDSWR 14 0 E9PBS1;P22234;P22234-2;D6RF62 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 0 ; 148.68 0.00039189 3613200.0 16176.7 16755.3 17895.2 13977.7 17693.9 16175.0 15914.6 15764.3 15408.6 17611.1 False True 15946.017291556547 16716.50413229256 16423.92573346964 15005.66668624031 16653.179589545838 15483.232955766625 16738.58011726415 16496.766928406552 13673.121208248705 20655.1551696843 0.7720114983672751 0.8093138974248655 0.7951489881603571 0.7264853041755028 0.8062480989727839 0.7496062280128237 0.8103826855695313 0.798675526418652 0.6619713623994861 1.0 14.334214277879196 -11.312614673150545 5.103383117829946 1.0191768317769694 0.7730997499187752 0.7036660508427555 0.04473939985462281 0.009682323461852025 0.00039892032048893436 0.042966354208865236 0.010095740344951495 4.868389609521916e-12 11.312614673150545 -0.2460770818581942 EIVMPS(ph)RNYT(ph)PYTRVLELTMK ddPTM_PC-9_AZD4547_30min_R2 1 EIVMPSRNYTPYTRVLELTMK 21 2 P0CAP1-10;P0CAP1-3;P0CAP1-4;P0CAP1 P0CAP1-10 MYZAP Myocardial zonula adherens protein 2 EIVMPS(0.674)RNY(0.505)T(0.544)PY(0.132)T(0.144)RVLELTMK 40.968 0.032688999999999996 14517000.0 47525.0 62214.0 60070.0 34129.0 45494.0 63363.0 71369.0 45186.0 64721.0 44268.0 True False 62636.96141859078 82323.45883892069 59273.43255095926 26261.086337793728 39177.94338360183 59400.901593388306 77720.70273992699 38203.54197098261 68142.01992945974 42718.190794130554 1.4662831045550049 1.9271288719987614 1.3875454800183948 0.6147518387272614 0.9171255302550136 1.3905294322892987 1.8193818908315225 0.8943155424136489 1.5951522913939136 1.0 15.38256292667774 -5.5163376976885425 24.773413611799242 1.1814392143812709 1.6868638837585517 0.25823668116968823 0.35136700604113524 350.32832053466376 1326822.957549465 0.09834017183953166 0.1787637096387891 3.0455259357441795e-06 5.5163376976885425 0.5054246693772808 EIVNFS(ph)PIAR ddPTM_PC-9_AZD4547_30min_R2 2 EIVNFSPIAR 10 0 O15264 O15264 MAPK13 Mitogen-activated protein kinase 13 1 EIVNFS(1)PIAR;EIVNFS(1)PIAR 84.89200000000001 0.012254000000000001 8796500.0 38044.0 29627.0 42159.0 62220.0 55486.0 49470.0 34846.0 50379.0 34613.0 38859.0 True False 50141.20063564161 39203.34836243778 41599.94411379875 47876.14028941734 47782.72665807647 46376.6330796351 37947.22649435327 42594.08314425117 36442.572516160006 37498.55823775908 1.3371500930174975 1.0454628179000776 1.1093744951481839 1.2767461614353102 1.2742550354899183 1.2367577650741852 1.0119649468587408 1.1358858885769416 0.9718392980630451 1.0 15.194547506805396 -7.26162468691252 24.999992921223004 1.0412463521291273 1.2065944397231307 0.5022438169005004 0.08899527585769765 16.8047595647373 2266895.977870461 0.0369869688930715 0.026728353533660362 5.4748889311565595e-08 7.26162468691252 0.16534808759400343 EIVNFS(ph)PIAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EIVNFSPIAR 10 0 O15264 O15264 MAPK13 Mitogen-activated protein kinase 13 1 EIVNFS(1)PIAR;EIVNFS(1)PIAR 83.087 0.014025 5302200.0 21508.0 22199.0 26434.0 27161.0 25746.0 28148.0 23944.1 20326.1 23933.1 18613.6 True False 25148.87959763646 24402.770011919994 27064.286811503254 25639.2572271501 20701.256119207414 26671.869328277997 21675.941507728003 19792.561412283136 24283.076310523164 21988.098334823477 1.1437496419509423 1.109817212945255 1.2308607319915612 1.1660515992210263 0.9414755111596879 1.2130139188088238 0.9858033731547808 0.9001488492043362 1.1043736452672233 1.0 14.424435216049993 -6.70953861504145 0.8994835284509942 0.9968198779026196 1.1611484573767976 0.3127405402333061 0.09089303139926422 0.7017371446123494 1.2372314009665004 0.055342194827081276 0.05421501317172921 1.9519171727463923e-07 6.70953861504145 0.164328579474178 EIVNFS(ph)PIAR ddPTM_PC-9_Lapatinib_30min_R1 1 EIVNFSPIAR 10 0 O15264 O15264 MAPK13 Mitogen-activated protein kinase 13 1 EIVNFS(1)PIAR 66.708 0.045499 3322900.0 28011.0 19287.0 22604.0 21796.0 18043.0 21948.0 17991.0 17799.0 21410.0 20483.0 True False 27611.5580034117 19242.34213648975 20745.586373963284 23398.950549324552 16981.74621390285 21009.33520328692 18922.48594936092 18626.006518444094 18998.580342705027 24023.459258118088 1.1493581214404462 0.8009813212053262 0.8635553336038758 0.9740042138776288 0.7068818038003549 0.8745341367183568 0.7876669944178238 0.7753257479831899 0.7908344980036529 1.0 14.552156286429808 -4.757728606767279 24.996065785562468 0.8344787506536313 1.1493585700896922 0.5330542305835522 0.0862048935470231 80.18792939523372 540073.1622120204 0.020567681817188207 0.148995670317205 1.7469134686291103e-05 4.757728606767279 0.3148798194360609 EIVSHLLT(ph)FSSFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EIVSHLLTFSSFSK 14 0 C9JCX3 C9JCX3 TAGLN3 1 EIVS(0.041)HLLT(0.624)FS(0.094)S(0.12)FS(0.12)K 78.324 0.040974000000000003 0.0 16348.0 17067.0 17760.0 21411.0 23894.0 21632.0 21404.0 12761.0 12352.0 17309.0 True False 19115.393512281982 18761.298968126423 18183.46575517508 20211.411085398588 19212.142224514173 20497.579839040394 19376.458168459467 12426.037271397126 12532.624632311821 20446.984682031394 0.9348759149352911 0.9175582248376047 0.8892981551042354 0.9884788099420925 0.939607600987622 1.002474455661595 0.947643795394795 0.6077197916774987 0.6129326561938184 1.0 14.319600484084434 -7.746079268770478 24.840107318793642 0.7077446913984528 0.9460472883864147 0.4294727790238786 0.1065799520278312 162.12670106285938 262189.45140690956 0.04783464153906192 0.0274840954469816 1.794406076400258e-08 7.746079268770478 0.23830259698796197 EKAEGDVAALNR ddPTM_PC-9_Lapatinib_30min_R1 2 EKAEGDVAALNR 12 1 A0A2R8YGX3;A0A2R8Y5V9;P67936;A0A2R8YH90 A0A2R8YGX3 TPM4 Tropomyosin alpha-4 chain 0 ; 96.334 0.005594699999999999 10344000.0 59424.0 73551.0 62513.0 60664.0 70171.0 58753.0 64525.0 62735.0 52685.0 63960.0 False True 58576.60286297307 73380.69717846002 57373.42244715832 65125.432929171584 66043.67974149395 56240.2711499324 67865.78877675033 65649.89712537729 46751.06050235473 75015.4007786571 0.7808610266018723 0.9782084267599863 0.7648219145885286 0.868160834350973 0.8804016116152548 0.7497163324618739 0.9046914109943549 0.8751522546561609 0.6232194991572456 1.0 16.194899193105687 EKDLLPS(ph)PAGPVPSK ddPTM_PC-9_AZD4547_30min_R2 1 EKDLLPSPAGPVPSK 15 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 EKDLLPS(1)PAGPVPSK 69.081 0.012495000000000001 6876000.0 96847.0 141540.0 129380.0 119530.0 118390.0 131250.0 133990.0 156780.0 122520.0 121360.0 True False 127642.33145725977 187290.03703444314 127664.33666460965 91974.205220091 101953.59206015353 123042.91675160905 145914.85042697605 132553.25344599315 128996.15707046255 117111.2233391093 1.0899239869406574 1.599249258050382 1.0901118870131052 0.7853577359854647 0.8705706349333824 1.0506500849651603 1.2459510392480697 1.1318578157293229 1.1014841566204037 1.0 16.837519817396164 -5.4973834171108615 24.067691774838508 1.0281582242994212 1.3446102782787077 0.3611605870418423 0.1668396894361647 493.1934828050401 465574.91176517407 0.04573275937963627 0.09451232832770183 3.181387591832518e-06 5.4973834171108615 0.31645205397928655 EKDLLPS(ph)PAGPVPSK ddPTM_PC-9_Lapatinib_30min_R1 1 EKDLLPSPAGPVPSK 15 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 EKDLLPS(0.98)PAGPVPS(0.02)K 61.086999999999996 0.022822 5369700.0 41454.0 87088.0 85831.0 92477.0 108880.0 98209.0 109580.0 103880.0 90362.0 96597.0 True False 40862.85835826742 86886.35308667077 78774.30649724133 99278.06707422865 102475.89246631603 94008.83000636064 115253.51622094226 108706.64403258468 80184.4800059557 113293.66274258816 0.3606808833704225 0.7669127379532533 0.6953107931219644 0.8762896765002292 0.9045156629735687 0.8297801283021088 1.0172988800159726 0.959512133344779 0.7077578574552837 1.0 16.789707638458943 -4.5680825789828505 0.9160616268127938 0.9026008640227647 7.894224038953751e-16 0.7095633316357999 0.09973171020284248 1.664106505879982 0.8463370705937572 0.033344246297100866 1.6448975182188021 2.7034442684588618e-05 4.5680825789828505 -0.902600864022764 down EKDLLPS(ph)PAGPVPSKDPK ddPTM_PC-9_AZD4547_30min_R2 2 EKDLLPSPAGPVPSKDPK 18 2 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 EKDLLPS(0.999)PAGPVPS(0.001)KDPK;EKDLLPS(0.999)PAGPVPS(0.001)KDPK 65.111 0.016678 45722200.0 196232.0 170376.0 208950.0 233126.0 243078.0 215266.0 197653.0 252429.0 202551.0 227310.0 True False 258629.69412083924 225446.71011572902 206179.18647449522 179382.40246079594 209330.8155316997 201805.3829901098 215243.73409540323 213421.89829135506 213257.43234393786 219351.94608777924 1.1790626832065672 1.0277853200605331 0.9399469216105673 0.8177835011730943 0.9543148317814818 0.9200072604295576 0.9812711395287461 0.9729656020737963 0.9722158209555957 1.0 17.74288798042347 -4.854677411995178 2.415828619394675 0.9406233000944363 1.212706674684795 0.6896881919076854 0.04807442943931046 0.26855197293783717 2.2232477523323264 0.013435819709255904 0.14523279110924903 1.3974059496933075e-05 4.854677411995178 0.2720833745903587 EKDLLPS(ph)PAGPVPSKDPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EKDLLPSPAGPVPSKDPK 18 2 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 EKDLLPS(1)PAGPVPSKDPK 66.711 0.038499 4564300.0 18841.0 17244.0 16749.0 23681.0 23600.0 19500.0 21879.0 23279.0 18906.0 18710.0 True False 22030.409173287546 18955.870358374174 17148.359680936213 22354.230344837877 18975.749414017522 18477.38567221191 19806.462729757277 22667.950916139318 19182.464483361993 22101.974891721482 0.9967620215485476 0.8576550489827172 0.7758745435621368 1.011413253989845 0.8585544733889405 0.8360060927918618 0.8961399525060536 1.025607486534148 0.867907260656014 1.0 14.431887664966943 -7.556228732228468 23.002274182651504 0.9602294465525547 0.8851849808645551 0.16320738259904766 0.07654854655770275 145.618334949413 100433.05466953419 0.0352486286174673 0.02035111636563104 2.7782496465682263e-08 7.556228732228468 -0.0750444656879996 EKEIS(ph)DDEAEEEK ddPTM_PC-9_AZD4547_30min_R2 1 EKEISDDEAEEEK 13 1 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 1 EKEIS(1)DDEAEEEK 125.39 0.00068598 5519200.0 13044.0 15244.0 9362.0 7008.2 9945.5 10717.0 13416.0 12904.0 9966.3 9729.6 True False 17191.720667945236 20171.324887332546 9237.853762977864 5392.5677656106545 8564.738996826214 10046.864295824731 14609.998009764216 10909.983304420835 10493.098271395287 9388.969665459754 1.8310550870337061 2.1484066522803924 0.9839049535927444 0.5743513886778112 0.9122128734033801 1.0700710145848322 1.5560810749566738 1.1620000589155808 1.1175984847408138 1.0 13.196751131562458 -5.264873722991637 24.968046056770397 1.0501205482679357 1.9897309135576429 0.7116539899873557 0.24001914349118084 155.4090578630891 1129849.4441448983 0.07046182319732153 0.1568264327027932 5.434083118575371e-06 5.264873722991637 0.9396103652897072 EKEIS(ph)DDEAEEEK ddPTM_PC-9_Lapatinib_30min_R1 2 EKEISDDEAEEEK 13 1 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 1 EKEIS(1)DDEAEEEK;EKEIS(1)DDEAEEEK 205.28 4.179600000000001e-09 23920000.0 85827.0 77711.0 41785.0 54278.0 49905.0 43959.0 63863.0 62090.0 45171.0 47267.0 True False 84603.09124125591 77531.06495404964 38349.59859476445 58269.785186100096 46969.68601700503 42078.97604343399 67169.51365594113 64974.92807068903 40083.366308282544 55437.03797068146 1.52611132084653 1.398542703436877 0.6917685359568831 1.0510984590648003 0.8472618259627347 0.7590408431577452 1.2116360490159042 1.1720490568967952 0.7230430732875937 1.0 15.75856255514923 -5.12610064835517 5.697654790916848 0.9442418397532968 1.4943805623445705 0.6047937401065497 0.1723076278676317 0.14537675829871224 6.0042669788407625 0.044657384739348056 0.12426011872644202 7.4799613127035e-06 5.12610064835517 0.5501387225912737 EKELS(ph)PPPGLPSK ddPTM_PC-9_AZD4547_30min_R2 4 EKELSPPPGLPSK 13 1 H0YHT2;A0A1B0GV47;Q7Z4S6-6;Q7Z4S6-3;Q7Z4S6-5;Q7Z4S6-2;Q7Z4S6;Q7Z4S6-4;H0YIM6;H0YI78 H0YHT2 KIF21A Kinesin-like protein KIF21A 1 EKELS(0.86)PPPGLPS(0.14)K;EKELS(0.818)PPPGLPS(0.182)K;EKELS(0.999)PPPGLPS(0.001)K;EKELS(1)PPPGLPSK 74.428 0.0091971 141458000.0 358983.0 322597.0 387400.0 449970.0 428400.0 426949.0 377914.0 402149.0 363378.0 425288.0 True False 473132.12668974075 426870.1715218332 382262.82287733705 346236.36846719927 368924.05472227186 400251.81153663085 411547.6138835743 340006.112514688 382585.4192291104 410398.79656759265 1.1528594397615781 1.0401350469153428 0.9314423581999427 0.8436583424780442 0.8989403911702506 0.9752753051036528 1.0027992706742561 0.8284773624054451 0.9322284139936522 1.0 18.64666697490295 -4.995391195670724 2.313708568860981 0.9205640178228764 1.1629857474481744 0.62463418788965 0.05596030837723429 0.2521812696620569 2.2236716419528872 0.015560240345214608 0.10385693560141362 1.0106686728754467e-05 4.995391195670724 0.24242172962529795 EKELS(ph)PPPGLPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EKELSPPPGLPSK 13 1 H0YHT2;A0A1B0GV47;Q7Z4S6-6;Q7Z4S6-3;Q7Z4S6-5;Q7Z4S6-2;Q7Z4S6;Q7Z4S6-4;H0YIM6;H0YI78 H0YHT2 KIF21A Kinesin-like protein KIF21A 1 EKELS(1)PPPGLPSK;EKELS(1)PPPGLPSK;EKELS(1)PPPGLPSK 117.4 0.0012512 51190800.0 430089.0 428067.0 425028.0 494579.0 521151.0 483047.0 522888.0 531791.0 472750.0 408987.0 True False 502894.5730550435 470562.66276375245 435162.2794476662 466869.3420767522 419035.20266375714 457715.1649643557 473356.26325870893 517832.0497291397 479663.07439486735 483133.10556068947 1.0409027393629346 0.9739814087416994 0.9007088821674686 0.9663368887440187 0.8673286881830528 0.9473893626750427 0.9797636672183037 1.071820671713608 0.9928176497824651 1.0 18.882061187881263 -7.535643634484009 5.723541613652097 1.0251062545962766 0.946584612574641 0.31641070592348086 0.04722530283141294 0.18842613051690724 21.455395415609473 0.022678261966428803 0.013432268705748979 2.9131065219003266e-08 7.535643634484009 -0.07852164202163558 EKELS(ph)PPPGLPSK ddPTM_PC-9_Lapatinib_30min_R1 3 EKELSPPPGLPSK 13 1 H0YHT2;A0A1B0GV47;Q7Z4S6-6;Q7Z4S6-3;Q7Z4S6-5;Q7Z4S6-2;Q7Z4S6;Q7Z4S6-4;H0YIM6;H0YI78 H0YHT2 KIF21A Kinesin-like protein KIF21A 1 EKELS(1)PPPGLPSK;EKELS(1)PPPGLPSK;EKELS(1)PPPGLPSK 90.87200000000001 0.0025455 94446000.0 305985.0 232848.0 237449.0 219192.0 234728.0 220562.0 214804.0 196544.0 224652.0 197464.0 True False 301621.59778922395 232308.85476213874 217926.85979964645 235312.11088307676 220921.7605330038 211129.0774151342 225925.50007595608 205676.15175914802 199349.3260695643 231595.38929575938 1.3023644326702786 1.0030806548806903 0.9409809947526309 1.0160483401617764 0.9539126025124585 0.9116290184236413 0.9755181256542091 0.8880839656807195 0.8607655216096933 1.0 17.821247006233925 -4.724010177521197 2.683002628304648 0.942466006761905 1.407596789891546 0.8475413690790548 0.04544112602727306 0.22158010532849529 1.841532750138346 0.012253045132037026 0.24822427674168074 1.8879471052764242e-05 4.724010177521197 0.46513078312964107 EKEPGEQASVPLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 EKEPGEQASVPLSPK 15 1 P42858 P42858 HTT Huntingtin 1 EKEPGEQASVPLS(1)PK;EKEPGEQASVPLS(1)PK 107.65 0.00038514 78551000.0 478920.0 392330.0 448010.0 455760.0 456750.0 428890.0 550300.0 432240.0 444300.0 474380.0 True False 631206.5978451656 519143.00006869447 442069.0946754665 350691.57342180767 393338.1465788929 402071.4404997927 599275.6339276417 365447.2398870786 467784.79094357276 457772.10059003375 1.378866464407918 1.13406430710731 0.9656968917626756 0.7660833261131307 0.8592444713688528 0.8783222917725936 1.309113493712746 0.7983169778499927 1.0218726530966684 1.0 18.804270013418382 -4.916827029920583 2.2320820387437283 0.9431052165003201 1.424724895113578 0.46392937867921746 0.14412469486250232 0.41891273764829096 3.0873024436336105 0.039547367802482 0.36230152612106303 1.2110803845777467e-05 4.916827029920583 0.48161967861325794 EKEPGEQASVPLS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EKEPGEQASVPLSPK 15 1 P42858 P42858 HTT Huntingtin 1 EKEPGEQASVPLS(1)PK;EKEPGEQASVPLS(1)PK;EKEPGEQASVPLS(1)PK;EKEPGEQASVPLS(1)PK 110.44 0.00024815 68791500.0 280810.0 313560.0 233532.0 325828.0 323818.0 302048.0 343280.0 286998.0 279324.0 241330.0 True False 328345.5867496884 344688.1645541529 239100.28855504253 307572.9135086279 260368.18744696348 286208.07115488494 310762.0332680231 279464.60659951624 283408.5850709085 285081.21863277163 1.151761551758511 1.2090875933786582 0.8387093674628927 1.078895744110134 0.913312313928185 1.0039527420554661 1.090082450041482 0.9802982039287181 0.9941327823352062 1.0 18.121013470998236 -5.234006096797165 24.98239987781277 0.9915961419095914 1.180424632827468 0.5491116273798364 0.06987420250938255 524.5438508313101 477679.6882114785 0.016904420097175805 0.04470086780593469 5.834369136988293e-06 5.234006096797165 0.18882849091787646 EKEPGEQASVPLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 EKEPGEQASVPLSPK 15 1 P42858 P42858 HTT Huntingtin 1 EKEPGEQASVPLS(1)PK;EKEPGEQASVPLS(1)PK 138.28 2.3554000000000002e-05 81000000.0 472510.0 423170.0 336450.0 402520.0 364720.0 334120.0 365510.0 320500.0 323210.0 255950.0 True False 465771.92075227946 422190.17586448696 308788.3797345585 432122.663567357 343267.88666710904 319830.46647176123 384434.31934583443 335391.60004277393 286806.68624781404 300190.6164680621 1.5515872089287437 1.4064069717828926 1.0286410127260295 1.4394942408645588 1.1434997226291717 1.0654245966605311 1.2806340313663176 1.1172621049547595 0.9554152279051267 1.0 18.195519355504096 -1.5228787452803376 0.2929625172865899 1.0443216400940034 4.92558602732066 0.5598686884903316 0.13057780697335136 43.183523415231555 0.6137090647606315 0.13864942514128423 87.12613343768399 0.029999999999999995 1.5228787452803376 3.881264387226657 EKEVDGLLTSEPMGS(ph)PVSSK ddPTM_PC-9_AZD4547_30min_R2 12 EKEVDGLLTSEPMGSPVSSK 20 1 H3BUF6;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 EKEVDGLLTSEPMGS(0.956)PVS(0.033)S(0.011)K;EKEVDGLLTSEPMGS(0.85)PVS(0.058)S(0.092)K;EKEVDGLLTSEPMGS(0.839)PVS(0.123)S(0.037)K;EKEVDGLLTSEPMGS(0.936)PVS(0.051)S(0.012)K;EKEVDGLLTSEPMGS(0.969)PVS(0.024)S(0.007)K;EKEVDGLLTS(0.002)EPMGS(0.824)PVS(0.075)S(0.099)K;EKEVDGLLTSEPMGS(0.896)PVS(0.084)S(0.02)K;EKEVDGLLTSEPMGS(0.88)PVS(0.085)S(0.035)K;EKEVDGLLTSEPMGS(0.938)PVS(0.026)S(0.036)K;EKEVDGLLTS(0.001)EPMGS(0.924)PVS(0.057)S(0.018)K;EKEVDGLLTSEPMGS(0.969)PVS(0.024)S(0.007)K;EKEVDGLLTSEPMGS(0.972)PVS(0.021)S(0.007)K 156.79 7.4028e-06 908553000.0 2816101.0 2704346.0 3187403.0 3898164.0 3755437.0 4000111.0 3157150.0 3725999.0 3278598.0 3430357.0 True False 3711562.5394603894 3578472.958131606 3145135.9536078796 2999502.5158334314 3234059.3961112145 3749983.426820546 3438130.2337900274 3150231.469489205 3451897.996889524 3310261.2455494166 1.1212294934276001 1.0810243339382337 0.9501171419133324 0.9061225967787907 0.9769801100923216 1.13283609620308 1.038628065507678 0.9516564512014366 1.0427871822897772 1.0 21.6585136482255 EKEVDGLLTSEPMGS(ph)PVSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 EKEVDGLLTSEPMGSPVSSK 20 1 H3BUF6;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 EKEVDGLLTSEPMGS(0.951)PVS(0.041)S(0.007)K;EKEVDGLLTSEPMGS(0.935)PVS(0.052)S(0.013)K;EKEVDGLLTSEPMGS(0.973)PVS(0.021)S(0.007)K;EKEVDGLLTSEPMGS(0.923)PVS(0.064)S(0.013)K;EKEVDGLLTSEPMGS(0.899)PVS(0.083)S(0.019)K;EKEVDGLLTSEPMGS(0.869)PVS(0.047)S(0.084)K;EKEVDGLLTSEPMGS(0.85)PVS(0.058)S(0.092)K 157.14 1.1058e-05 710534500.0 941352.0 870915.0 911685.0 1071672.0 1145414.0 1014980.0 1099098.0 1011678.0 993207.0 860070.0 True False 1100704.301050506 957373.6855232813 933423.0279846176 1011629.692247504 920978.3491231983 961752.6620298288 994983.4806595704 985122.5244614437 1007730.7734119607 1015993.8826896261 1.0833768980346883 0.9423026081503952 0.9187289843848077 0.995704511103385 0.9064802109685006 0.9466126503476524 0.9793203459311831 0.9696146219439263 0.991866969458723 1.0 19.95446028497765 -8.211208740582062 1.5412182871936022 0.9999147760541212 0.9622396046023732 0.05062505080586377 0.046567993339607254 1.138370731589569 5.021863714361445 0.04301476386199426 0.013255589746014058 6.148812633283963e-09 8.211208740582062 -0.037675171451747924 EKEVDGLLTSEPMGS(ph)PVSSK ddPTM_PC-9_Lapatinib_30min_R1 11 EKEVDGLLTSEPMGSPVSSK 20 1 H3BUF6;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 EKEVDGLLTSEPMGS(0.905)PVS(0.036)S(0.059)K;EKEVDGLLTS(0.003)EPMGS(0.942)PVS(0.045)S(0.01)K;EKEVDGLLTSEPMGS(0.794)PVS(0.073)S(0.133)K;EKEVDGLLTSEPMGS(0.85)PVS(0.058)S(0.092)K;EKEVDGLLTSEPMGS(0.907)PVS(0.074)S(0.019)K;EKEVDGLLTS(0.001)EPMGS(0.935)PVS(0.052)S(0.013)K;EKEVDGLLTSEPMGS(0.869)PVS(0.049)S(0.082)K;EKEVDGLLTSEPMGS(0.836)PVS(0.124)S(0.04)K;EKEVDGLLTSEPMGS(0.967)PVS(0.024)S(0.009)K;EKEVDGLLTSEPMGS(0.994)PVS(0.004)S(0.001)K;EKEVDGLLTSEPMGS(0.968)PVS(0.025)S(0.007)K 178.57 7.4518e-10 821091400.0 1654506.0 1583293.0 1757917.0 1603224.0 1809542.0 1679094.0 1587841.0 1604919.0 1820922.0 1413296.0 True False 1630912.4410407585 1579626.9823357312 1613387.850015852 1721130.4411584802 1703108.2972564532 1607283.063779289 1670051.6376143198 1679489.395784859 1615830.5892012683 1657582.330501457 0.9839103681488749 0.9529704517650459 0.9733379876990875 1.0383378306390358 1.0274652823677384 0.9696550416853494 1.0075225868926163 1.0132162758255119 0.9748116636308751 1.0 20.660649098700546 -5.551128662667948 24.879801917792996 1.0047139022097116 0.9671188535343318 0.3637872034063383 0.02087101725341217 195.68693315825914 172341.1723910985 0.005780500503188636 0.010012329315543314 2.81106790920758e-06 5.551128662667948 -0.03759504867537977 EKFPEFCSSPS(ph)PPVEVK ddPTM_PC-9_AZD4547_30min_R2 2 EKFPEFCSSPSPPVEVK 17 1 Q68E01-4;Q68E01-3;Q68E01-2;Q68E01 Q68E01-4 INTS3 Integrator complex subunit 3 1 EKFPEFCS(0.001)S(0.007)PS(0.993)PPVEVK;EKFPEFCSS(0.209)PS(0.791)PPVEVK 151.21 2.1666999999999998e-05 50226000.0 192996.0 188464.0 213330.0 211244.0 219620.0 239140.0 213246.0 238010.0 227559.0 217990.0 True False 254364.7134338206 249381.3023856104 210501.10481265426 162544.95948726594 189129.55391714623 224186.537996037 232224.48088775916 201231.02342569793 239587.30416909425 210358.23645099235 1.20919778433815 1.1855076682186836 1.0006791669490689 0.7727054677278321 0.8990831883172218 1.0657369151707365 1.1039476504732013 0.9566110974341582 1.138949005331253 1.0 17.682488781511275 -5.259793636814885 5.257358377428188 0.9854844278846665 1.2007611045268582 0.4072368111345972 0.09898374587350703 0.16911072105843247 16.292004446061167 0.02817765843377802 0.0692312072681524 5.498020605807682e-06 5.259793636814885 0.21527667664219174 EKFPEFCSSPS(ph)PPVEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EKFPEFCSSPSPPVEVK 17 1 Q68E01-4;Q68E01-3;Q68E01-2;Q68E01 Q68E01-4 INTS3 Integrator complex subunit 3 1 EKFPEFCSS(0.016)PS(0.983)PPVEVK;EKFPEFCSS(0.017)PS(0.983)PPVEVK;EKFPEFCS(0.001)S(0.017)PS(0.982)PPVEVK 171.42 5.4252e-06 50272000.0 249517.0 253681.0 261137.0 272481.0 316289.0 251364.0 292781.0 236183.0 264409.0 209953.0 True False 291755.2999146114 278864.7731606778 267363.4964475876 257214.77296532143 254314.44094958433 238182.02933896802 265046.6641291225 229983.4465065735 268275.4814123175 248015.81691296693 1.1763576353559475 1.1243830197270697 1.078009861529961 1.037090199193153 1.0253960578604053 0.9603501595325682 1.0686683915088044 0.9272934660747008 1.0816869857395428 1.0 17.92007260413871 -5.222326879340862 0.9544935462147017 1.0057518070233453 1.2069609995171608 0.6318392848111798 0.042887035624122036 0.6799164282454517 0.7776733609277924 0.014314558123539847 0.1224201609586969 5.993398028578488e-06 5.222326879340862 0.20120919249381553 EKFPEFCSSPS(ph)PPVEVK ddPTM_PC-9_Lapatinib_30min_R1 2 EKFPEFCSSPSPPVEVK 17 1 Q68E01-4;Q68E01-3;Q68E01-2;Q68E01 Q68E01-4 INTS3 Integrator complex subunit 3 1 EKFPEFCSS(0.028)PS(0.972)PPVEVK;EKFPEFCSSPS(1)PPVEVK 123.92 1.9625999999999998e-05 43193000.0 183650.0 194766.0 209227.0 195393.0 225597.0 213427.0 185146.0 199697.0 199607.0 157742.0 True False 181031.11732271456 194315.03129338744 192025.1636995758 209762.8530319405 212327.82800076727 204299.22473263703 194731.95395366446 208975.6516497406 177125.15770510607 185007.4945219968 0.9785069398969162 1.0503089715118759 1.0379318102529334 1.133807328043137 1.147671495954031 1.1042753984668794 1.052562516220182 1.1295523578094513 0.9573944999511708 1.0 17.497224188912 -4.747755403394382 1.5183385979391888 1.0814649821859377 0.936078543277086 0.16813764432805733 0.058635570475071154 1.920462283283654 3.918121357078915 0.016452815963933318 0.4328152690038624 1.7874940160791482e-05 4.747755403394382 -0.14538643890885172 EKGS(ph)ETDSAQDQPVK ddPTM_PC-9_Lapatinib_30min_R1 1 EKGSETDSAQDQPVK 15 1 P30419;B7Z8J4;K7EN42 P30419 NMT1 Glycylpeptide N-tetradecanoyltransferase 1 1 EKGS(0.99)ET(0.008)DS(0.001)AQDQPVK 120.11 0.0023340999999999995 0.0 7284.6 7754.7 6341.4 6704.6 10384.0 8774.9 10512.0 8114.1 7274.3 7622.7 True False 7180.7202681679655 7736.744468597344 5820.034570511889 7197.6786498899455 9773.23353572949 8399.617982290969 11056.259924388974 8491.110707978378 6454.991732225093 8940.273538390706 0.8031879827091433 0.865381180494618 0.6509906599076525 0.8050848353780419 1.0931694084931458 0.9395258373495966 1.2366802734739542 0.949759609872834 0.7220127778536656 1.0 13.126103257730923 -6.156801288283718 6.280495846508549 0.9969781996079689 0.774555102605703 0.37844080907989497 0.13134176808034795 0.2618321328924221 13.424411557645188 0.04010859337740061 0.05207031985412957 6.969453289465581e-07 6.156801288283718 -0.2224230970022658 EKGS(ph)PGQNDQELK ddPTM_PC-9_AZD4547_30min_R2 3 EKGSPGQNDQELK 13 1 Q3T7B4;Q9H3H1-6;Q9H3H1-3;Q9H3H1-2;Q9H3H1-5;Q9H3H1-4;Q9H3H1 Q3T7B4 TRIT1 tRNA dimethylallyltransferase, mitochondrial 1 EKGS(1)PGQNDQELK;EKGS(1)PGQNDQELK;EKGS(1)PGQNDQELK 107.69 0.0030259 24722000.0 108193.0 114880.0 129385.0 140814.0 129861.0 132665.0 142218.0 150564.0 119151.0 156844.0 True False 142596.1234457985 152012.71339915786 127669.2703613429 108351.50785461282 111832.04171402659 124369.43657792205 154875.12648722754 127297.79341652339 125449.0786084123 151352.93929959845 0.9421430737036027 1.004359175993625 0.8435202576979727 0.7158863802448816 0.7388825234021953 0.8217180132308934 1.0232713497598949 0.8410658822062342 0.8288512875200246 1.0 17.207557167255217 -9.712631351785637 15.634396837905816 0.9999990395355854 0.8608175709945197 0.15552022130441356 0.09629247677252763 0.0 0.0 0.10343348452955062 0.025086304820060443 1.9380663817137578e-10 9.712631351785637 -0.13918146854106572 EKGS(ph)PGQNDQELK ddPTM_PC-9_Lapatinib_30min_R1 1 EKGSPGQNDQELK 13 1 Q3T7B4;Q9H3H1-6;Q9H3H1-3;Q9H3H1-2;Q9H3H1-5;Q9H3H1-4;Q9H3H1 Q3T7B4 TRIT1 tRNA dimethylallyltransferase, mitochondrial 1 EKGS(1)PGQNDQELK 79.837 0.0063365 26864000.0 109560.0 81790.0 96534.0 76379.0 84808.0 91059.0 81651.0 68985.0 92158.0 72697.0 True False 107997.65430915647 81600.62028016255 88597.34715201586 81996.16645287463 79819.76017894321 87164.61883889652 85878.48925858873 72190.29494212399 81778.19557323727 85262.57958733628 1.2666477466651378 0.9570508032375128 1.0391117367175562 0.9616899564818375 0.9361640307537508 1.0223080190719769 1.007223680942254 0.8466820414244907 0.9591334905539671 1.0 16.37962508370844 -4.760069271967356 24.998771447415777 0.9687896943678019 1.2666481081320944 0.749232756272594 0.05149449018640947 17.751637510895236 323775.01110299106 0.013288429488096979 0.0808159144681956 1.7375236636294993e-05 4.760069271967356 0.29785841376429245 EKGSET(ph)DSAQDQPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EKGSETDSAQDQPVK 15 1 P30419;B7Z8J4;K7EN42 P30419 NMT1 Glycylpeptide N-tetradecanoyltransferase 1 1 EKGS(0.42)ET(0.573)DS(0.007)AQDQPVK 72.421 0.014182 3666900.0 17738.0 22201.0 18004.0 26719.0 29759.0 22295.0 27956.0 28578.0 22256.0 16399.0 True False 20740.693058530567 24404.968558702447 18433.28364055022 25222.02105416677 23927.93757676896 21125.81095189562 25307.805296087303 27827.857780893923 22581.451895784652 19372.008885587427 1.0706526711311508 1.2598057693881966 0.9515421838498325 1.3019827320506594 1.2351810139097703 1.0905327927870714 1.3064109894620195 1.4364982973757336 1.1656742483008573 1.0 14.241685949339699 -5.794696610892559 24.999977000752484 1.2365609625886198 1.1105801499529453 0.1432178161929113 0.1343881726737872 336.8147491624869 253187.48105392072 0.03726645204180693 0.055278832810758315 1.604365775923831e-06 5.794696610892559 -0.1259808126356745 EKHFQQQEQER ddPTM_PC-9_AZD4547_30min_R2 1 EKHFQQQEQER 11 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 0 58.273999999999994 0.032791 2189500.0 16378.0 10382.0 20598.0 24729.0 19958.0 24525.0 19500.0 22111.0 17410.0 23733.0 False True 21585.863316437237 13737.778468924602 20324.857061505874 19028.11110924143 17187.176200156613 22991.44787301499 21235.4622234945 18694.253010233184 18330.257056780567 22902.11489376299 0.9425270730047637 0.5998475919211224 0.887466382724375 0.830845151092287 0.7504624040130571 1.0039006432229682 0.927227128236861 0.8162675410961392 0.8003739891189048 1.0 14.483193209568638 -6.73903638464753 24.999474763497943 0.8991752270058706 0.7973113866953084 0.20356569955720094 0.10492005503820345 415.30662455672024 463439.05645187426 0.03420402576502154 0.03417995205024315 1.82374290502368e-07 6.73903638464753 -0.10186384031056217 EKHFQQQEQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EKHFQQQEQER 11 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 0 70.41199999999999 0.014547999999999998 1318600.0 10680.0 10828.0 10112.0 12741.0 12498.0 15285.0 11623.0 13966.0 13089.0 10397.0 False True 12487.913060384853 11902.93228024099 10353.108429973548 12027.16307687933 10049.106617643683 14483.427692295325 10521.985296767163 13599.407298200173 13280.4018630448 12281.893797393284 1.0167742260591193 0.9691447000435124 0.8429570065302875 0.9792596545194017 0.818204975830072 1.1792503608335463 0.8567070738716496 1.1072728296255516 1.0812991939291512 1.0 13.584245412688674 -6.751565668290917 24.999993564551716 1.0398480314566485 0.9261324210779754 0.27867344599708854 0.09606291332547218 288.3157318697885 730007.1785805799 0.030811927165778987 0.030445485268131477 1.7718801045086489e-07 6.751565668290917 -0.11371561037867306 EKIGS(ph)FIILWK ddPTM_PC-9_Lapatinib_30min_R1 1 EKIGSFIILWK 11 1 Q5TCS8-3;Q5TCS8-6;Q5TCS8 Q5TCS8-3 AK9 Adenylate kinase 9 1 EKIGS(1)FIILWK 106.6 0.0078894 0.0 3088.3 3507.3 3382.8 2563.3 2767.2 3410.8 2318.7 2487.9 2504.0 1293.3 True False 3044.2602756751403 3499.1790623378693 3104.6792419856206 2751.8136329181316 2604.438736524522 3264.9280349631376 2438.7509405137657 2603.496916525483 2221.9731517110413 1516.845181786073 2.0069683526241935 2.306879505143441 2.0468003453917993 1.8141690832797406 1.7170102577362683 2.1524464554244824 1.607778413906524 1.7163893505993053 1.4648648249616918 1.0 10.56685812775028 -9.127285677592118 0.16370908321058278 0.40349125209578923 2.454936940793467 0.7991562666003037 0.1606785246377987 4.308638113491012 0.32020777118738747 2.448532813204252 1.1044204365429335 7.459579081398544e-10 9.127285677592118 2.0514456886976777 EKLQEEGGGS(ph)DEEETGSPSEDGMQSAR ddPTM_PC-9_AZD4547_30min_R2 2 EKLQEEGGGSDEEETGSPSEDGMQSAR 27 1 Q13610;Q13610-2 Q13610 PWP1 Periodic tryptophan protein 1 homolog 1 EKLQEEGGGS(0.979)DEEET(0.011)GS(0.005)PS(0.005)EDGMQSAR;EKLQEEGGGS(0.871)DEEET(0.1)GS(0.02)PS(0.007)EDGMQS(0.002)AR 76.109 7.3751e-05 24223200.0 111100.0 93081.0 123257.0 169254.0 160808.0 131600.0 104935.0 130405.0 119708.0 139311.0 True False 146427.48897644226 123167.61295183685 121622.53164530703 130235.10524823274 138482.58494813 123371.0311962802 114274.01171396903 110253.9036587877 126035.52049127445 134433.76429296812 1.089216609730101 0.9161955227514181 0.9047022694407195 0.9687678235685988 1.030117587471094 0.9177086712190906 0.8500395143658593 0.8201355086547614 0.9375287611273639 1.0 17.036536004371406 -6.988360040839522 21.487352385100102 0.8864996291147421 0.9732246777850825 0.22857238475763186 0.0677335093782626 56.33793421970929 103996.61525314124 0.023803146142678887 0.020959326535901678 1.0271644004251097e-07 6.988360040839522 0.08672504867034037 EKLQEEGGGS(ph)DEEETGSPSEDGMQSAR ddPTM_PC-9_Lapatinib_30min_R1 3 EKLQEEGGGSDEEETGSPSEDGMQSAR 27 1 Q13610;Q13610-2 Q13610 PWP1 Periodic tryptophan protein 1 homolog 1 EKLQEEGGGS(1)DEEETGSPSEDGMQSAR;EKLQEEGGGS(1)DEEETGSPSEDGMQSAR;EKLQEEGGGS(0.977)DEEET(0.019)GS(0.003)PS(0.001)EDGMQSAR 155.06 1.8012e-12 67678000.0 148804.0 111427.0 143222.0 123613.0 126637.0 124801.0 114371.0 116114.0 139228.0 116088.0 True False 146682.02767268821 111168.99762755456 131446.84001290795 132703.9123808797 119188.46063792137 119463.55215534037 120292.5707583991 121509.08033499731 123546.67650416338 136153.656122463 1.0773271306115755 0.8164966023943121 0.9654301159175519 0.974662863709804 0.8753966954124072 0.8774171444055033 0.8835059901013772 0.8924408186711221 0.9074062351512595 1.0 17.05487619790501 -4.740458057203793 24.88718996483888 0.9077226015133613 1.0773277930357277 0.47727009734150194 0.0523755000307286 1322.5435306496884 1568662.1383085614 0.012737514883458943 0.5634866417713228 1.817782603349556e-05 4.740458057203793 0.16960519152236642 EKLQSFDS(ph)PER ddPTM_PC-9_AZD4547_30min_R2 2 EKLQSFDSPER 11 1 E9PGM9;P78332;P78332-2 E9PGM9 RBM6 RNA-binding protein 6 1 EKLQS(0.019)FDS(0.981)PER;EKLQS(0.115)FDS(0.885)PER 58.32 0.034245 31694000.0 152837.0 130505.0 243733.0 256127.0 262240.0 230945.0 171433.0 225817.0 190500.0 225880.0 True False 201435.98679291268 172688.18908562924 240500.9411676869 197080.87727270316 225832.50259189666 216503.97264152707 186690.2048902738 190922.1714084311 200569.44108654218 217972.0099525206 0.9241369423385606 0.7922493769876452 1.10335699166179 0.9041568103887834 1.0360619358471221 0.9932650191585914 0.8564870550624334 0.8759022383195825 0.9201614516021157 1.0 17.733783363130414 -10.295198355564619 14.235282742173968 1.0000048945259952 0.9346709673978183 0.05077031051082559 0.08559869670843226 0.0 0.0 0.08360092272518793 0.02027620204676763 5.067592029932477e-11 10.295198355564619 -0.06533392712817687 EKLQSFDS(ph)PER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EKLQSFDSPER 11 1 E9PGM9;P78332;P78332-2 E9PGM9 RBM6 RNA-binding protein 6 1 EKLQS(0.028)FDS(0.972)PER 56.286 0.038325 2436100.0 15482.0 15871.0 18684.0 20777.0 19248.0 20654.0 20134.0 23809.0 20589.0 21215.0 True False 18102.79681656164 17446.567992215074 19129.497419464595 19612.932049942858 15476.492572924115 19570.867880711015 18226.761762463215 23184.038977720724 20890.07517443882 25061.11156215241 0.7223461246587601 0.6961609802880048 0.7633140043298873 0.7826042353030558 0.617550124803598 0.7809257714756425 0.7272926309457672 0.9251001864072755 0.8335653876577152 1.0 14.613162785016897 -8.09631143132641 0.8922014529811784 0.9832069578131136 0.7188037056858758 0.680588633422821 0.059782488019110645 0.3070805412546353 0.4844298257026678 0.053887611189596646 0.020425683981041488 8.011033884230052e-09 8.09631143132641 -0.2644032521272378 EKLQSFDS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 2 EKLQSFDSPER 11 1 E9PGM9;P78332;P78332-2 E9PGM9 RBM6 RNA-binding protein 6 1 EKLQS(0.001)FDS(0.999)PER;EKLQS(0.001)FDS(0.999)PER 133.04 0.00037655 21035700.0 92711.0 75366.0 92591.0 62219.0 70727.0 73726.0 60949.0 64339.0 79023.0 54093.0 True False 91388.92413888499 75191.49465747326 84978.5253915958 66794.79281649952 66566.97691463209 70572.91084370014 64104.640994252615 67328.42482106724 70122.59759091919 63442.902975608195 1.4404908957905216 1.1851837026811656 1.339448880897953 1.0528331725643139 1.04924229176942 1.112384640892508 1.010430449862908 1.0612443892574226 1.1052867113895959 1.0 15.953171165923845 -4.266419959217744 0.5371832476277035 1.040566580264313 1.8993962968494646 0.7335769641868942 0.07158119192781576 3.559435975631924 0.5214674221629148 0.03859984165499992 2.1547191896129054 5.414770332899395e-05 4.266419959217744 0.8588297165851517 EKPCVS(ph)PTVGEK ddPTM_PC-9_AZD4547_30min_R2 1 EKPCVSPTVGEK 12 1 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 EKPCVS(0.938)PT(0.062)VGEK 55.851000000000006 0.037272 10604000.0 56826.0 51720.0 46293.0 83092.0 74192.0 59577.0 51768.0 68616.0 60601.0 76023.0 True False 74895.48594577253 68437.47856027541 45679.12457269112 63936.423158602855 63891.72144714003 55851.64077189044 56375.251712095574 58012.973838820486 63804.245140606465 73361.45790960039 1.0209105445813582 0.9328805684942556 0.622658353232009 0.8715260707794067 0.8709167356770713 0.7613213036294015 0.7684587154955936 0.7907827283136458 0.869724334257768 1.0 16.162734689393687 -5.0112932996518715 24.04668943043154 0.8094903012602884 0.9989032218501068 0.3262987364402471 0.0934280703542122 308.24165489318125 656352.8768772439 0.022330136586340314 0.06851539576819039 9.743314032879778e-06 5.0112932996518715 0.1894129205898184 EKPCVS(ph)PTVGEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EKPCVSPTVGEK 12 1 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 EKPCVS(0.827)PT(0.173)VGEK;EKPCVS(0.925)PT(0.075)VGEK 97.631 0.018875 30759900.0 87172.1 91930.4 97582.2 123819.5 124726.8 127579.0 131628.0 130042.6 118059.0 104731.2 True False 101928.61480254438 101056.64256515227 99908.92973055429 116882.29484323546 100287.47889882558 120888.53265000632 119159.24293580577 126629.11954152399 119785.38952931503 123718.13750827666 0.8238777018100958 0.8168296468122279 0.807552811113653 0.9447466410122454 0.8106125821051615 0.977128617393864 0.9631509602044737 1.023529145296522 0.9682120337553697 1.0 16.91669749435556 -6.691978875139937 0.823702110932648 1.004978449220684 0.818562423944041 0.7170462189686246 0.04426897185191114 0.319745591744311 0.47730697695272817 0.027353621110121594 0.027993674501270452 2.0324558708191696e-07 6.691978875139937 -0.18641602527664292 EKPCVSPT(ph)VGEK ddPTM_PC-9_AZD4547_30min_R2 2 EKPCVSPTVGEK 12 1 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 EKPCVS(0.018)PT(0.982)VGEK;EKPCVS(0.082)PT(0.918)VGEK 164.2 0.0024948 23682000.0 79261.0 69890.0 98060.0 122908.0 105154.0 113962.0 84851.0 103249.0 89117.0 94735.0 True False 104464.34926878309 92480.57572655952 96759.66032873413 94573.45950967055 90555.18219016262 106835.93812454757 92402.57462183229 87294.239475988 93827.54268403855 91418.35648508985 1.1427064900890118 1.0116193211332005 1.0584270386059218 1.0345127953059983 0.9905579762302114 1.1686486416103126 1.0107660887220495 0.9548874299684605 1.0263534184115597 1.0 16.480196262020996 -7.506224896098422 24.88013874305289 0.9909375911065165 1.0622478606056716 0.2878137208908067 0.05377477151275392 898.8968396600008 1342920.4540346244 0.022437636823005883 0.01468632489655991 3.117274908924558e-08 7.506224896098422 0.07131026949915509 EKPCVSPT(ph)VGEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EKPCVSPTVGEK 12 1 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 EKPCVS(0.286)PT(0.714)VGEK;EKPCVS(0.323)PT(0.677)VGEK 128.95 0.0019543 30475000.0 69871.0 76715.0 71383.0 89165.0 92306.0 100297.0 84198.0 88077.0 86159.0 67614.0 True False 81698.78028484533 84330.75820822755 73085.04144153518 84169.37412683052 74219.30192416521 95037.24875722238 76222.15589926894 85765.07207529564 87418.91237818595 79871.88296787061 1.0228728464772716 1.0558253427197974 0.9150284020590136 1.0538048058875564 0.9292294004640004 1.1898711439600367 0.9543052331686006 1.0737830246195101 1.0944891885590229 1.0 16.285400104957546 -6.691155717957337 24.99999999909347 1.0603710496828211 0.9974972533869626 0.17839138685390787 0.07189408578859299 88.44555019437253 31458.47432094164 0.022488110714630985 0.022488102268074323 2.0363118193579867e-07 6.691155717957337 -0.06287379629585854 EKPCVSPT(ph)VGEK ddPTM_PC-9_Lapatinib_30min_R1 4 EKPCVSPTVGEK 12 1 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 EKPCVS(0.373)PT(0.627)VGEK;EKPCVS(0.393)PT(0.607)VGEK;EKPCVS(0.145)PT(0.855)VGEK;EKPCVS(0.114)PT(0.886)VGEK 154.65 0.0028663 45986100.0 192235.0 189833.0 191509.0 192510.0 208853.0 204717.0 192881.0 190617.0 215549.0 174966.0 True False 189493.69364841876 189393.4533518047 175763.86926611827 206667.8275945342 196568.67716079665 195961.73112863515 202867.43440601867 199473.76170157047 191271.60178840402 205208.63997245958 0.9234196653408459 0.9229311854375264 0.8565130069070532 1.0071107513907331 0.9578966908370794 0.9549389887040554 0.9885910965213008 0.9720534268359325 0.9320835702340505 1.0 17.646731948963705 -5.767012718398154 24.999999904962024 0.9713126558985719 0.9031522751810548 0.5973877548266915 0.02714364183529454 93.11433136816355 417679.61580964713 0.007475951568793538 0.011445786878612065 1.7099652376933167e-06 5.767012718398154 -0.06816038071751707 EKPDS(ph)DDDLDIASLVTAK ddPTM_PC-9_AZD4547_30min_R2 2 EKPDSDDDLDIASLVTAK 18 1 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 EKPDS(1)DDDLDIASLVTAK;EKPDS(0.999)DDDLDIASLVTAK 100.85 0.00026528 4153800.0 34509.0 29457.0 25340.6 32474.0 32641.0 32752.0 37253.0 34041.0 34778.0 33816.0 True False 45482.14416820932 38978.39918696899 25004.567086746087 24987.621018298614 28109.36057467243 30704.012262466324 40568.444831376415 28780.745634360646 36616.29407930579 32632.112132789312 1.3937848700424167 1.1944798126567733 0.7662564710796352 0.765737164564062 0.8614018136578925 0.9409140339283892 1.2432062217208593 0.8819761809239818 1.1220939034011563 1.0 14.994004749292557 -5.027701742453348 4.627141670079058 0.9445725163754125 1.3604901726282483 0.5111451754757446 0.14160895259766357 0.14869717897078785 8.000421247051541 0.038854164120051445 0.1317864332273712 9.38206111327803e-06 5.027701742453348 0.41591765625283583 EKPDS(ph)DDDLDIASLVTAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EKPDSDDDLDIASLVTAK 18 1 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 EKPDS(1)DDDLDIASLVTAK 90.53399999999999 0.0029204 0.0 29671.0 24234.0 13982.0 30949.0 31574.0 28345.0 33729.0 29423.0 22075.0 24101.0 True False 34693.714271037374 26639.791363073513 14315.383907030287 29215.02786801178 25387.30135585548 26858.53830147932 30533.94494318676 28650.67742624544 22397.80511320301 28470.32051658898 1.2185923319978842 0.9357039499274741 0.5028177992829077 1.0261573223592224 0.8917111186388963 0.9433872824097461 1.072483357726702 1.0063349097018899 0.786707164050097 1.0 14.797171114466318 -6.9265305980594505 5.228934987859499 0.9722167369856521 0.900053497142901 0.01392872405984924 0.1797190402220017 0.9421591434370591 46.849349010817875 0.06692889473086727 0.058592659374412805 1.1843209231586647e-07 6.9265305980594505 -0.07216323984275119 EKPDS(ph)DDDLDIASLVTAK ddPTM_PC-9_Lapatinib_30min_R1 5 EKPDSDDDLDIASLVTAK 18 1 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 EKPDS(0.998)DDDLDIAS(0.002)LVTAK;EKPDS(0.995)DDDLDIAS(0.005)LVTAK;EKPDS(0.975)DDDLDIAS(0.025)LVTAK;EKPDS(1)DDDLDIASLVTAK;EKPDS(1)DDDLDIASLVTAK 143.35 8.3862e-05 23534100.0 283077.0 239474.0 205719.0 234994.0 229088.0 205540.0 215302.0 221319.0 205688.0 200894.0 True False 279040.2700700354 238919.5126662383 188805.57791830416 252276.24267700352 215613.4942443369 196749.53333714197 226449.28407922306 231602.28870473243 182521.25144933732 235618.2602255713 1.1842896633006867 1.0140110212065334 0.8013198032170741 1.0706990300135675 0.915096707860916 0.8350351672607292 0.9610854602798177 0.9829556015013685 0.7746481587403239 1.0 17.84609182564268 -4.872713624142086 3.497078183802804 0.9201342180132819 1.1929889505072282 0.4592923430343915 0.08836256366837428 0.22156584806888527 4.578231304639868 0.021489636721292216 0.13808010525289025 1.3405603679587545e-05 4.872713624142086 0.2728547324939463 EKPDSDDDLDIAS(ph)LVTAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EKPDSDDDLDIASLVTAK 18 1 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 EKPDS(0.356)DDDLDIAS(0.643)LVT(0.001)AK 88.755 0.00071213 4687200.0 27695.0 31808.0 22996.0 37442.0 32544.0 30304.0 34362.0 34738.0 28989.0 24923.0 True False 32383.21649881632 34965.68802825135 23544.31185281566 35344.24612860183 26167.23681905874 28714.804892856897 31106.982600663603 33826.16430795341 29412.909283200075 29441.342609640553 1.0999232245683135 1.1876390452656143 0.7997023833113537 1.2004970900012004 0.8887922390635232 0.9753225344911495 1.0565748652535172 1.1489341622918057 0.9990342381182314 1.0 14.845555843475074 EKPELSEPSHLNGPS(ph)SDPEAAFLSR ddPTM_PC-9_AZD4547_30min_R2 1 EKPELSEPSHLNGPSSDPEAAFLSR 25 1 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 EKPELSEPSHLNGPS(0.591)S(0.409)DPEAAFLS(0.001)R 79.873 4.0311e-05 18873000.0 10323.0 9028.4 20475.0 25055.0 17502.0 14921.0 14393.0 18012.0 12145.0 15482.0 True False 13605.499268261183 11946.653740015296 20203.488121872666 19278.95684589123 15072.14940651072 13987.98751124389 15673.949117064427 15228.65927458371 12786.959905491094 14939.979892354047 0.9106772141791287 0.7996432275072425 1.3523102619577396 1.2904272284702187 1.0088466996012702 0.9362788713258331 1.0491278589394895 1.0193226084847278 0.85588869580977 1.0 13.866890585961698 -6.5052707034210995 24.78247564649166 0.9775238765832841 1.0944000740586932 0.10696223446691056 0.15794166840398874 1755.8991636902326 2471347.6801359435 0.05451079546452345 0.06051825690955662 3.124131433795161e-07 6.5052707034210995 0.11687619747540912 EKPELSEPSHLNGPSS(ph)DPEAAFLSR ddPTM_PC-9_AZD4547_30min_R2 2 EKPELSEPSHLNGPSSDPEAAFLSR 25 1 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 EKPELSEPSHLNGPS(0.031)S(0.969)DPEAAFLSR;EKPELSEPSHLNGPS(0.268)S(0.732)DPEAAFLSR 125.34 1.6705999999999998e-09 70050000.0 90335.0 75411.0 159527.0 194335.0 173656.0 169172.0 121652.0 202870.0 150080.0 163302.0 True False 119059.65091527387 99786.1310075199 157411.56774691003 149534.06819582006 149546.86192075352 158593.64809678687 132478.79232884914 171521.10298882984 158012.92240560733 157584.84668526027 0.755527282093743 0.6332216143016587 0.9989004086243373 0.9489114679565618 0.9489926542203593 1.0064016397055071 0.8406823061702453 1.0884365254446327 1.0027164776902822 1.0 17.265769286749517 -5.266229571660402 24.995546457685784 0.9763767579390324 0.6943744386332784 0.7529697827189394 0.06527986251862082 165.25548377187417 862318.604759184 0.016638928835512216 0.03652878445124404 5.417144599529796e-06 5.266229571660402 -0.28200231930575403 EKPELSEPSHLNGPSS(ph)DPEAAFLSR ddPTM_PC-9_Lapatinib_30min_R1 2 EKPELSEPSHLNGPSSDPEAAFLSR 25 1 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 EKPELSEPSHLNGPS(0.271)S(0.729)DPEAAFLSR;EKPELSEPSHLNGPS(0.031)S(0.968)DPEAAFLS(0.001)R 152.26 1.6705999999999998e-09 60555000.0 134485.0 136187.0 193236.0 155611.0 197102.0 199274.0 166628.0 175285.0 218932.0 138118.0 True False 132567.21923847139 135871.66736880422 177348.88199253063 167055.15204307874 185508.84787744176 190751.5155503823 175255.18252293425 183429.38100935268 194273.57270383465 161991.5122693337 0.8183590447508121 0.8387579414833688 1.0948035456182614 1.031258673388554 1.1451763446038281 1.177540186384772 1.081878797646804 1.1323394568005236 1.1992824190740776 1.0 17.30555869786933 -5.264018053267317 3.0979208658023936 1.116288445001883 0.813463749903835 0.7853523097525108 0.05832956626935527 0.10544353734709684 2.055666608300203 0.015545387679882533 0.045021054548972886 5.444800187817888e-06 5.264018053267317 -0.3028246950980481 EKPLALYMFSSNDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EKPLALYMFSSNDK 14 1 P30838;A8MYB8;I3L3I9;C9JMC5;E9PNN6 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 0 123.72 0.00024397 3611500.0 35260.0 34364.0 35027.0 40240.0 46616.0 41733.0 41086.0 34344.0 30350.0 35574.0 False True 41228.821583255594 37775.4308162358 35862.17652063725 37985.48325984023 37481.92943575598 39544.4480132523 37194.03664311928 33442.50639047589 30793.811333441055 42023.284596370926 0.9810946949828871 0.8989166643936737 0.8533882314314446 0.903915141919216 0.891932408324714 0.9410127835811127 0.8850816160698516 0.7958089595253567 0.7327797345974324 1.0 15.358901308949756 -7.613717321524118 5.491372763269669 0.8241069662492371 0.907667090028834 0.14249436013265127 0.07064863224179584 0.31296576120779235 14.918351619348424 0.03274104645603442 0.018528639101383117 2.43378762469345e-08 7.613717321524118 0.08356012377959687 EKQEASES(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 1 EKQEASESPVK 11 1 Q01167-2;Q01167;E9PPI7;Q01167-3 Q01167-2 FOXK2 Forkhead box protein K2 1 EKQEAS(0.012)ES(0.988)PVK 99.161 0.022572 9924700.0 13278.0 13730.0 14949.0 13967.0 15076.0 19845.0 14364.0 18850.0 17501.0 14964.0 True False 17500.127800442875 18167.95399521622 14750.766492496921 10747.123937998913 12982.95763070253 18604.089012843313 15642.368173244877 15937.165629907993 18426.067131000378 14440.114914687121 1.2119105633046865 1.258158546698094 1.0215130959583871 0.7442547376868832 0.8990896338018399 1.288361562408412 1.0832578733383165 1.1036730472067235 1.2760332753487387 1.0 13.817794602812592 -6.758442505859553 24.9997043059926 1.1525567506800456 1.023817028145554 0.13254166670705825 0.15753330316201972 186.09415028558547 1552386.1810527188 0.0590578863782673 0.05663166602203248 1.7440442277415685e-07 6.758442505859553 -0.1287397225344915 EKQEASES(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EKQEASESPVK 11 1 Q01167-2;Q01167;E9PPI7;Q01167-3 Q01167-2 FOXK2 Forkhead box protein K2 1 EKQEASES(1)PVK 71.513 0.013937999999999999 45612000.0 95261.0 102090.0 78494.0 96501.0 101070.0 76355.0 89825.0 73067.0 69517.0 60304.0 True False 111386.80580948712 112224.82051069476 80365.59465015274 91094.36183046311 81266.05903706569 72350.80938470464 81316.12572331657 71149.06867088593 70533.55461175703 71236.63783379857 1.5636168297184727 1.5753806457363313 1.1281497428002265 1.278757176089562 1.1407902100414489 1.015640428644394 1.1414930321814787 0.998770728580468 0.9901303143519787 1.0 16.120331806503152 -4.115991907626287 0.4426145846016192 1.0009043628584224 2.5519014224820995 0.8446340913982839 0.08334986344574599 3.161363349626622 0.3083684022285814 0.055967388262579666 2.904058040271954 7.656108726959632e-05 4.115991907626287 1.550997059623677 EKQEASES(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 2 EKQEASESPVK 11 1 Q01167-2;Q01167;E9PPI7;Q01167-3 Q01167-2 FOXK2 Forkhead box protein K2 1 EKQEAS(0.122)ES(0.878)PVK;EKQEAS(0.005)ES(0.995)PVK 140.1 0.00056874 98374000.0 182783.0 198915.0 175453.0 171343.0 237019.0 165220.0 181920.0 215010.0 181907.0 150380.0 True False 180176.48090170327 198454.42453880102 161027.93160816588 183944.13580349198 223078.008417283 158153.92574663114 191338.9274586039 225000.14953259478 161418.71809436913 176372.9826312456 1.0215650844801434 1.1251974173035477 0.9129965894200326 1.0429269441344986 1.264808277828394 0.896701543440436 1.084853953276101 1.2757064385706802 0.9152122716655401 1.0 17.428270055688593 -6.012047756896952 24.925386239590793 1.0853111128609625 1.021699848755301 0.02869578116991256 0.12758650248212736 1991.3529293819602 4119887.7429589457 0.036196855445315305 0.04939460805396722 9.726402621720218e-07 6.012047756896952 -0.06361126410566142 EKQLS(ph)PEAQAR ddPTM_PC-9_AZD4547_30min_R2 2 EKQLSPEAQAR 11 1 A0A0U1RRH6;O94880;O94880-2;B4DG57 A0A0U1RRH6 PHF14 PHD finger protein 14 1 EKQLS(1)PEAQAR;EKQLS(1)PEAQAR 156.08 0.0034544000000000003 24489000.0 50859.0 49965.0 68017.0 85632.0 78752.0 68969.0 63505.0 65824.0 52955.0 61320.0 True False 67031.10406708284 66115.20913117104 67115.05013848167 65890.86540121162 67818.64415846951 64656.35752717515 69156.8219745137 55652.41328504323 55754.09319022482 59173.20546435536 1.1327948780375081 1.1173166741997338 1.1342135280960959 1.1135253681821045 1.1461039439433778 1.092662751997147 1.168718534543008 0.9405002289180874 0.9422185726242237 1.0 15.852656428807904 -7.766641608137105 24.99999406179267 0.9560194971391304 1.1276857469149284 0.908483762382785 0.024478349510330937 31.521889600511116 151478.78477804767 0.011840409236068222 0.005956144919405663 1.7114270496211005e-08 7.766641608137105 0.17166624977579803 EKQLS(ph)PEAQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EKQLSPEAQAR 11 1 A0A0U1RRH6;O94880;O94880-2;B4DG57 A0A0U1RRH6 PHF14 PHD finger protein 14 1 EKQLS(1)PEAQAR;EKQLS(1)PEAQAR 104.94 0.012648999999999999 16986400.0 40543.0 40749.0 40584.0 44841.0 51947.0 43472.0 46812.0 42795.0 32990.0 31923.0 True False 47406.129139249344 44794.29141924085 41551.6764756771 42328.704146483484 41768.35825465967 41192.25179191772 42377.62847046929 41671.67659505055 33472.41633905174 37710.38719767102 1.257110644098004 1.1878502117848138 1.1018628967629194 1.122468033133791 1.107608840920076 1.092331711578441 1.123765403105872 1.1050450470480497 0.8876179436608644 1.0 15.202674343216298 -1.522878745280745 0.1638410330965116 0.9594994777043335 2.0454811704539355 0.6330809894757159 0.0570495659991612 43.5294010345906 0.45875680727275303 0.1651385882637043 11.473113028928534 0.02999999999997185 1.522878745280745 1.085981692749602 EKQLS(ph)PEAQAR ddPTM_PC-9_Lapatinib_30min_R1 3 EKQLSPEAQAR 11 1 A0A0U1RRH6;O94880;O94880-2;B4DG57 A0A0U1RRH6 PHF14 PHD finger protein 14 1 EKQLS(1)PEAQAR;EKQLS(1)PEAQAR;EKQLS(1)PEAQAR 95.428 0.030033999999999998 25549300.0 75234.0 66693.0 71749.0 63708.0 66975.0 69098.0 58599.0 56122.0 68187.0 48035.0 True False 74161.14936377428 66538.57645610567 65850.0741791493 68393.29884365795 63035.6621779162 66142.83961530519 61632.9694928909 58729.63300343385 60507.06201905783 56337.785747385766 1.3163660655089835 1.1810648141987592 1.168843846196155 1.213986278238342 1.1188878182142832 1.1740404550488461 1.0939899159198114 1.042455471480064 1.0740049722643834 1.0 15.781815241912598 -1.5228787452808066 0.13561363330401213 0.9494655253464168 2.0676120537279843 0.8289335074435444 0.03611910920640741 31.468722386049205 0.2873331888436109 0.1729857303093574 6.775761899160534 0.0299999999999676 1.5228787452808066 1.1181465283815675 EKQPVAGSEGAQYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EKQPVAGSEGAQYR 14 1 Q9UGI8-2;Q9UGI8;F8W7T0 Q9UGI8-2 TES Testin 0 68.262 0.042024 2669200.0 11602.0 9832.7 10328.0 10923.0 14747.0 15019.0 11681.0 17257.0 14166.0 9035.1 False True 13565.989450054783 10808.825473949539 10574.258689158118 10311.019722843808 11857.43121222527 14231.37720056157 10574.491116883524 16804.022035302904 14373.150950560992 10673.09210818775 1.2710458518059427 1.0127173423021116 0.9907399450854723 0.9660761490977688 1.1109649473678735 1.3333883991916569 0.9907617220665992 1.5744286533807645 1.3466716865991235 1.0 13.381690580350107 -6.616437207307567 5.131092414316845 1.2678805328225993 1.0502167224629737 0.2017222566710506 0.17725404122037094 0.30384888146998346 13.12649447455485 0.059243350655569745 0.05920824975501732 2.4185930061728466e-07 6.616437207307567 -0.21766381035962556 EKQPVAGSEGAQYR ddPTM_PC-9_Lapatinib_30min_R1 1 EKQPVAGSEGAQYR 14 1 Q9UGI8-2;Q9UGI8;F8W7T0 Q9UGI8-2 TES Testin 0 83.87700000000001 0.0097867 3075200.0 15485.0 13139.0 15182.0 11995.0 11135.0 14153.0 10599.0 14338.0 12616.0 8552.0 False True 15264.181060398792 13108.577452757749 13933.794564214762 12877.15231414699 10480.061192252302 13547.70918225441 11147.764358694702 15004.195823442398 11195.053227630395 10030.201805176284 1.5218219290983168 1.3069106392249066 1.3891838703608088 1.2838378094747287 1.0448504821551905 1.350691585812645 1.1114197476008585 1.4959016892062118 1.1161343954069762 1.0 13.292063012458483 -1.5228787453335912 0.029450993888998852 4.9973267057008785e-06 3.0914972432478502 0.373487220682688 0.1390253982216557 1721.1265994947637 3.9025909752753445 131.81012317252566 313.91656350917174 0.029999999996321365 1.5228787453335912 3.0914922459211445 EKQS(ph)DDEVYAPGLDIESSLK ddPTM_PC-9_AZD4547_30min_R2 1 EKQSDDEVYAPGLDIESSLK 20 1 Q15459;Q15459-2 Q15459 SF3A1 Splicing factor 3A subunit 1 1 EKQS(1)DDEVYAPGLDIESSLK 80.835 0.0045152000000000005 0.0 7944.2 6092.8 9229.4 9803.8 7593.6 7889.8 8600.4 10852.0 8974.9 10381.0 True False 10470.290350374933 8062.178448802136 9107.012125617173 7543.685377200097 6539.3597150771275 7396.449558756928 9365.818938817538 9175.072754151806 9449.294891378513 10017.56434973048 1.0451932211103423 0.8048042585340663 0.9091044297471564 0.7530458616323296 0.6527893893941462 0.738348095458546 0.9349397330369554 0.915898559154118 0.9432726919925144 1.0 13.290244156774 -7.335869203072264 8.514073846565324 0.9421125665489126 0.8105162670198243 0.28592360034002917 0.10114110585718591 0.541748181588044 57.759745746947914 0.045386698345038334 0.030541097079519974 4.614565309852444e-08 7.335869203072264 -0.13159629952908836 EKQS(ph)DDEVYAPGLDIESSLK ddPTM_PC-9_Lapatinib_30min_R1 2 EKQSDDEVYAPGLDIESSLK 20 1 Q15459;Q15459-2 Q15459 SF3A1 Splicing factor 3A subunit 1 1 EKQS(1)DDEVYAPGLDIESSLK;EKQS(0.99)DDEVY(0.01)APGLDIESSLK 82.479 0.00050248 9072500.0 71810.0 63473.0 63621.0 70138.0 69787.0 59005.0 59329.0 65334.0 70969.0 60977.0 True False 70785.97623165886 63326.03216826947 58390.32696416198 75296.182493509 65682.26586652103 56481.493697373044 62400.76532097348 68369.6561534932 62975.72388329913 71516.79320325475 0.9897811837071767 0.8854708010787525 0.8164561685283256 1.0528461794912 0.9184173803745413 0.7897654686060861 0.8725330447022001 0.955994432792628 0.8805725349613842 1.0 16.1259944274034 -10.510455444473767 3.9855725112360787 1.0000085296825452 0.905205737111839 0.12399223623623079 0.07414273684497123 106522083.61252996 201556675.09285253 12649.871545150594 0.018854114179195688 3.087056339471367e-11 10.510455444473767 -0.09480279257070612 EKS(ph)PVREPVDNLSPEER ddPTM_PC-9_AZD4547_30min_R2 1 EKSPVREPVDNLSPEER 17 2 Q86U06-3;Q86U06-5;Q86U06-2;Q86U06 Q86U06-3 RBM23 Probable RNA-binding protein 23 1 EKS(0.984)PVREPVDNLS(0.016)PEER 50.534 0.025726 24120000.0 29199.0 22006.0 31502.0 47610.0 45796.0 44417.0 29996.0 34081.0 25900.0 29589.0 True False 38483.67462307062 29119.009149215424 31084.262896958848 36634.250067167464 39438.015896501296 41639.59796842837 32665.585890048253 28814.564553469198 27269.02112410203 28553.098116190675 1.3477933100803845 1.0198196017371528 1.088647640633186 1.28302189549072 1.3812166979574965 1.458321538313811 1.1440294764905263 1.009157200252475 0.9550284530644145 1.0 14.801359671350163 -7.643856880031185 3.6553424287492935 0.984603834799254 1.2534940442776803 0.4948993244661428 0.12369919072899027 0.23080124406607835 5.868536741221909 0.07300325717630377 0.038929339030251135 2.270612999822303e-08 7.643856880031185 0.26889020947842635 EKS(ph)PVREPVDNLSPEER ddPTM_PC-9_Lapatinib_30min_R1 1 EKSPVREPVDNLSPEER 17 2 Q86U06-3;Q86U06-5;Q86U06-2;Q86U06 Q86U06-3 RBM23 Probable RNA-binding protein 23 1 EKS(0.982)PVREPVDNLS(0.018)PEER 50.387 0.026036 32233000.0 53030.0 57886.0 68724.0 54766.0 52303.0 55723.0 52490.0 61532.0 51138.0 58724.0 True False 52273.78247548906 57751.96852350527 63073.7780023117 58793.67433402038 49226.64037165442 53339.85718665741 55207.67536445751 64391.00135360985 45378.299932986905 68874.36515518856 0.7589729844725993 0.8385118090508397 0.9157801724951381 0.8536365337313202 0.7147309490365009 0.7744515258539428 0.801570733030539 0.9349051887233119 0.6588561626773615 1.0 16.07167949535038 -11.28468113466485 6.457874989091727 1.0054610401661976 0.8114069143863815 0.3396135548079994 0.080927967459956 0.006450635721194026 0.00023793039515451292 0.07943672147266749 0.018847246896157948 5.191810893443689e-12 11.28468113466485 -0.19405412577981618 EKS(ph)RS(ph)RSHS(ph)AGK ddPTM_PC-9_AZD4547_30min_R2 1 EKSRSRSHSAGK 12 3 Q08170;A0A0D9SEM4 Q08170 SRSF4 Serine/arginine-rich splicing factor 4 3 EKS(1)RS(0.994)RS(0.011)HS(0.995)AGK 72.315 0.031068000000000002 15413000.0 0.0 3487.2 65195.0 159630.0 82220.0 20414.0 6824.1 91900.0 8420.8 21828.0 True False 0.0 4614.369204087255 64330.47170234377 122829.76975891508 70805.17222050692 19137.5093528941 7431.4316799666085 77698.96665191234 8865.906296596073 21063.808363926128 0.0 0.21906623552414303 3.0540760051974325 5.831318232522154 3.361461089902804 0.9085493478790375 0.35280570120898347 3.688742572543509 0.42090709065601933 1.0 14.362478680634409 -6.770407530914286 24.924967331465076 1.3846601427945167 2.5834569907374174 0.10343674520498936 1.7696597600488992 533.051091058449 1481487.048729257 0.6894668020820411 0.6168523970297114 1.6966508111975678e-07 6.770407530914286 1.1987968479429008 EKT(ph)PELPEPSVK ddPTM_PC-9_AZD4547_30min_R2 8 EKTPELPEPSVK 12 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 EKT(0.998)PELPEPS(0.002)VK;EKT(1)PELPEPSVK;EKT(0.999)PELPEPS(0.001)VK;EKT(1)PELPEPSVK;EKT(1)PELPEPSVK;EKT(1)PELPEPSVK;EKT(1)PELPEPSVK;EKT(0.802)PELPEPS(0.198)VK 130.2 0.0015761 2399774200.0 1166499.0 1100791.0 1122264.0 1284713.0 1204864.0 1336215.0 1234490.0 1224964.0 1177393.0 1241748.0 True False 1537421.4173135157 1456600.1636087447 1107382.0460857288 988542.266467988 1037589.4310665155 1252661.2648171524 1344357.2184759888 1035673.960672394 1239627.5902845494 1198274.7804786738 1.2830291034743828 1.2155810898622752 0.9241470021119562 0.824971269171747 0.8659027528327272 1.0453873228615835 1.1219106338355544 0.8643042293343387 1.0345102896927836 1.0 20.192527344711074 -5.19666186073767 4.71107449178652 0.9558285410198419 1.262568882851356 0.6284152629149359 0.08922499468938125 0.1424550011536875 6.2999515775358725 0.024823132213082466 0.06979519537209687 6.358257895949253e-06 5.19666186073767 0.306740341831514 EKT(ph)PELPEPSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 10 EKTPELPEPSVK 12 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 EKT(1)PELPEPSVK;EKT(1)PELPEPSVK;EKT(0.993)PELPEPS(0.007)VK;EKT(1)PELPEPSVK;EKT(0.926)PELPEPS(0.074)VK;EKT(1)PELPEPSVK;EKT(1)PELPEPSVK;EKT(1)PELPEPSVK;EKT(1)PELPEPSVK;EKT(1)PELPEPSVK 170.74 0.00019981 1840295100.0 1654495.0 1695757.0 1516998.0 1846636.0 1903487.0 1685580.0 1986056.0 1828812.0 1718450.0 1520793.0 True False 1934568.325734215 1864100.5480924149 1553168.9855669553 1743174.9717946933 1530512.3866457622 1597185.2175059956 1797922.3978797372 1780807.6227864812 1743579.0802620046 1796500.7323092383 1.0768536249064053 1.0376286046353476 0.8645523809892901 0.9703168723755544 0.8519408643259654 0.8890534742242823 1.0007913526250956 0.9912646239210907 0.970541814375323 1.0 20.77675809275147 -10.604712157241359 18.060092802747405 0.9999999999687134 0.9577758510055018 0.024508792726787076 0.06961499958053977 0.0 0.0 0.07170612150184966 0.017391288997382345 2.484779427843365e-11 10.604712157241359 -0.04222414896321158 EKT(ph)PELPEPSVK ddPTM_PC-9_Lapatinib_30min_R1 5 EKTPELPEPSVK 12 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 EKT(1)PELPEPSVK;EKT(1)PELPEPSVK;EKT(0.981)PELPEPS(0.019)VK;EKT(1)PELPEPSVK;EKT(0.98)PELPEPS(0.02)VK 142.54 0.0006652 1427389000.0 895033.0 739344.0 724071.0 799029.0 834184.0 755157.0 722070.0 782993.0 723170.0 663830.0 True False 882269.6652910513 737632.0943931594 664540.6773748879 857792.2581426069 785118.9371888444 722860.6954669466 759455.2514843548 819373.7132364773 641718.9792822981 778572.1310021266 1.1331893734180443 0.947416514181837 0.8535377146360672 1.1017505302155028 1.0084087343047987 0.9284440923110464 0.9754462319462093 1.0524056546717562 0.8242254683022366 1.0 19.5704711787616 -8.248363833738582 24.973766464926438 0.9121127140826928 0.9938933425730966 0.13615745296406512 0.08752313609809696 1426.3743081942448 2724331.096374504 0.05877165665470464 0.021915865278034585 5.6446389245346056e-09 8.248363833738582 0.0817806284904038 EKTATCHSSS(ph)SPPIDAASAEPYGFR ddPTM_PC-9_AZD4547_30min_R2 2 EKTATCHSSSSPPIDAASAEPYGFR 25 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 EKT(0.006)AT(0.007)CHS(0.018)S(0.155)S(0.407)S(0.407)PPIDAASAEPYGFR;EKT(0.063)AT(0.063)CHS(0.049)S(0.112)S(0.355)S(0.355)PPIDAAS(0.002)AEPYGFR 60.516999999999996 0.0013189 24836000.0 12385.0 9478.0 56582.0 207350.0 112701.0 65220.0 24773.0 98943.0 36171.0 59617.0 True False 16323.17237599677 12541.578147608097 55831.68570997797 159548.66102556564 97054.41151086558 61141.78308982823 26977.749008339964 83653.63283395163 38082.92521543995 57529.82697600249 0.283734077330107 0.21800131873922698 0.9704824200717157 2.77332071747962 1.6870276969779527 1.0627840600899494 0.46893499296622665 1.4540915075035112 0.6619683600182831 1.0 15.812022510796483 -3.38702479345969 10.855725009765521 1.0937688381208308 0.8867591246391898 0.0 0.7299061073947732 0.0 0.0 0.18246415012032663 0.0 0.0004101806854922273 3.38702479345969 -0.207009713481641 EKTATCHSSS(ph)SPPIDAASAEPYGFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EKTATCHSSSSPPIDAASAEPYGFR 25 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 EKT(0.022)AT(0.022)CHS(0.039)S(0.056)S(0.43)S(0.43)PPIDAASAEPYGFR 47.553999999999995 0.015616 5424700.0 7239.3 2342.5 19206.0 23751.0 29714.0 31571.0 17122.0 21504.0 25968.0 11985.0 True False 8464.7705073075 2575.047918956828 19663.943879160608 22420.308471780943 23891.755003733768 29915.36118243086 15500.080207454814 20939.54278537135 26347.732873370594 14157.785626792194 0.5978880264501792 0.18188210973358768 1.3889138031549624 1.583602765488464 1.687534734140981 2.1129971855075294 1.0948096415672843 1.4790125615227117 1.8610066268774506 1.0 13.789308015375292 -5.34152523631929 4.761425170817722 1.568507421585908 0.391540554249688 0.6629511815455001 0.32436029255480925 0.11289767621710212 4.563571562822927 0.08443601892038388 0.18620398054715404 4.5548571768072985e-06 5.34152523631929 -1.1769668673362201 EKTPELPEPS(ph)VK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EKTPELPEPSVK 12 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 EKT(0.022)PELPEPS(0.978)VK 117.93 0.0029346 94729000.0 38395.0 46010.0 39404.0 48227.0 47312.0 38229.0 49306.0 41612.0 41458.0 35401.0 True False 44894.51516418317 50577.56873050316 40343.54080050217 45524.9975440436 38041.55323203379 36224.203941691725 44635.378735472885 40519.72909155843 42064.24481916964 41818.92106583819 1.073545515282493 1.2094422199672648 0.9647197912396344 1.0886220013273584 0.9096732355228043 0.8662156511561274 1.0673488841378898 0.9689329150258478 1.0058663338766014 1.0 15.351868220218108 -5.272882514721952 24.732338231350468 0.9826760344325379 1.141493868121122 0.4534384475162302 0.0691878915946755 490.5303144265229 1060196.5075188072 0.01821095166938058 0.038470254842677847 5.3347919268023095e-06 5.272882514721952 0.15881783368858404 EKVEPEVLST(ph)DTQTSPEPGTR ddPTM_PC-9_Lapatinib_30min_R1 1 EKVEPEVLSTDTQTSPEPGTR 21 1 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 EKVEPEVLS(0.142)T(0.34)DT(0.231)QT(0.118)S(0.118)PEPGT(0.052)R 47.105 0.045569 13566000.0 36041.0 50232.0 72779.0 41829.0 57977.0 56803.0 46341.0 54497.0 62538.0 47325.0 True False 35527.04873089009 50115.690890244856 66795.3915550642 44905.244197453474 54566.90684716763 54373.66810426038 48740.310231745585 57029.1295710797 55494.31188566498 55505.06319340127 0.6400686115264838 0.9029030507653375 1.2034107829464677 0.8090296923180882 0.9830978240135546 0.9796163624713178 0.8781236778690865 1.0274581504820197 0.9998063004144536 1.0 15.760331760216422 -4.805717353642158 4.085907027316425 0.9797793069584217 0.6196131812886625 0.5321637197969321 0.09670585526897174 0.15823459782159582 4.871623205310101 0.02345826751282321 0.15695645581792944 1.5641652972715467e-05 4.805717353642158 -0.36016612566975925 EKVEPEVLSTDTQT(ph)SPEPGTR ddPTM_PC-9_AZD4547_30min_R2 1 EKVEPEVLSTDTQTSPEPGTR 21 1 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 EKVEPEVLS(0.013)T(0.182)DT(0.135)QT(0.407)S(0.257)PEPGT(0.006)R 115.06 2.5454e-06 8526100.0 34604.0 29345.0 45133.0 54885.0 43945.0 42559.0 37291.0 53775.0 39995.0 48791.0 True False 45607.35219208659 38830.19737724833 44534.506930621654 42232.11121479703 37843.995295915556 39897.77900214653 40609.82675776066 45465.309376567755 42109.05404858923 47082.841940824605 0.9686618375629817 0.8247207640110491 0.9458755057010835 0.896974555356617 0.8037746604905295 0.8473953006552044 0.8625185966641635 0.9656449675172577 0.8943609245489766 1.0 15.52291378425442 -8.579324424420422 0.9784482371164225 0.9958530162962432 0.8785115700876331 0.28248661480301607 0.05374521443966413 0.805540085643254 1.6788255108125318 0.051309329936173854 0.017132104731099232 2.6343627425665303e-09 8.579324424420422 -0.11734144620861009 EKVEPEVLSTDTQT(ph)SPEPGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EKVEPEVLSTDTQTSPEPGTR 21 1 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 EKVEPEVLST(0.002)DT(0.003)QT(0.447)S(0.447)PEPGT(0.1)R 103.59 7.603199999999999e-05 6518000.0 41779.0 41270.0 39249.0 41034.0 51390.0 46072.0 49485.0 40980.0 41549.0 33169.0 True False 48851.3595271366 45367.0128560718 40184.84501266139 38734.99801402296 41320.49840620172 43655.90321487933 44797.42255962512 39904.318421899115 42156.57552201459 39182.27713434047 1.2467718341035843 1.157845234480026 1.0255872795469114 0.9885846573239231 1.0545711333858963 1.1141747342861308 1.1433082974231576 1.0184277520441973 1.075909278510701 1.0 15.257913623886859 -5.009475396946187 3.213936614693783 1.05685133098122 1.2420911818787927 0.6422243771414057 0.04677665039240668 0.17245691935104074 3.499171612504712 0.013200536155747098 0.06077154820223296 9.7841838122737e-06 5.009475396946187 0.18523985089757278 EKVEPEVLSTDTQT(ph)SPEPGTR ddPTM_PC-9_Lapatinib_30min_R1 1 EKVEPEVLSTDTQTSPEPGTR 21 1 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 EKVEPEVLSTDT(0.002)QT(0.491)S(0.491)PEPGT(0.015)R 150.94 4.4248e-05 12009000.0 114170.0 100390.0 126270.0 95053.0 102900.0 111530.0 83315.0 90744.0 112680.0 77214.0 True False 112541.91486378649 100157.55312294312 115888.56801629567 102043.51470751262 96847.62430918384 106760.1218891284 87628.64303657424 94960.29751725889 99988.7918269968 90560.33701881213 1.2427285340204521 1.1059759318490319 1.2796834887244521 1.1268014018798878 1.0694265005779036 1.178883884530499 0.9676271745584506 1.0485859554335886 1.1041124085727076 1.0 16.46659170669522 -6.483475915296866 0.8822599380527971 1.038466944471342 1.2031495842134332 0.49112740212331907 0.06738020346686042 0.5295258209817553 0.9034534696097511 0.03675311170261374 0.04642816172945869 3.2849146097464815e-07 6.483475915296866 0.1646826397420913 EKVEPEVLSTDTQTS(ph)PEPGTR ddPTM_PC-9_AZD4547_30min_R2 1 EKVEPEVLSTDTQTSPEPGTR 21 1 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 EKVEPEVLSTDTQT(0.19)S(0.793)PEPGT(0.017)R 171.05 3.3784000000000002e-09 7799100.0 42890.0 50846.0 61887.0 64322.0 62169.0 61518.0 56473.0 67849.0 55899.0 57769.0 True False 56528.12783257982 67280.97515227704 61066.337943752544 49493.55666499363 53537.90746505345 57671.26973505136 61498.98759730282 57364.49606491395 58853.70701992975 55746.52489351508 1.0140206576205015 1.2069088661722795 1.0954286040322543 0.8878321430714177 0.9603810742879408 1.0345267233287252 1.1031896197077016 1.0290237135765763 1.0557376828842675 1.0 15.766594253189485 -5.5435896525304535 24.99135064764592 1.0124020893927401 1.120640817369625 0.2832751785997585 0.06933529491619041 274.18136314241445 330846.5675971606 0.019598327841942896 0.033949062593243554 2.860291842253148e-06 5.5435896525304535 0.10823872797688483 EKVEPEVLSTDTQTS(ph)PEPGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EKVEPEVLSTDTQTSPEPGTR 21 1 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 EKVEPEVLS(0.01)T(0.051)DT(0.158)QT(0.158)S(0.497)PEPGT(0.127)R 75.661 0.0006697 6706600.0 51048.0 47312.0 50362.0 60389.0 82259.0 64585.0 68950.0 63749.0 64009.0 54790.0 True False 59689.41815604176 52008.82268588492 51562.82107894858 57005.600113779605 66140.93945117241 61198.048904605435 62418.556845228966 62075.65629764875 64945.010531869164 64722.99328259863 0.9222289503116939 0.803560219454003 0.796669289595599 0.8807627277817215 1.0219079201479855 0.945537988909099 0.9643953976709968 0.9590974265761957 1.0034302685646992 1.0 15.98199071003214 -6.082219216141946 4.7952220190129795 0.9770114816596256 0.8369835535149008 0.7405639002568948 0.038542055271669526 0.10975753493593152 4.437097948890481 0.011401347417651609 0.015139048660231228 8.275243539190564e-07 6.082219216141946 -0.14002792814472476 EKVEPEVLSTDTQTS(ph)PEPGTR ddPTM_PC-9_Lapatinib_30min_R1 2 EKVEPEVLSTDTQTSPEPGTR 21 1 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 EKVEPEVLSTDT(0.002)QT(0.262)S(0.733)PEPGT(0.004)R;EKVEPEVLSTDT(0.001)QT(0.234)S(0.738)PEPGT(0.028)R 138.99 6.3341999999999994e-06 14388000.0 104547.0 86490.0 100074.0 85936.0 93502.0 96702.0 87277.0 94072.0 95873.0 73855.0 True False 103056.1406084281 86289.73771892957 91846.3020168112 92256.02011409243 88002.39619200488 92566.28088337209 91795.77601035929 98442.92854671995 85074.77315255294 86620.73834439856 1.1897398080201467 0.9961787369653563 1.060326935238489 1.0650569583843577 1.0159506588608485 1.0686387885004447 1.0597436337402841 1.136482214632218 0.9821524819414611 1.0 16.402424849360408 -8.511462426779575 0.007947689700209907 2.0324244850935395e-06 2.085235952583535 0.15503481891509807 0.056954445903546536 5792.60001802286 30.710350996751004 4068.878341574808 3984.910113439418 3.0799067897668537e-09 8.511462426779575 2.08523392015905 EKVIET(ph)PENDFK ddPTM_PC-9_AZD4547_30min_R2 2 EKVIETPENDFK 12 1 A0A024QZ33;Q9H0G5 A0A024QZ33 CCDC55;NSRP1 Nuclear speckle splicing regulatory protein 1 1 EKVIET(1)PENDFK;EKVIET(1)PENDFK 124.25 0.00023636 23729000.0 118163.0 122214.0 120428.0 133442.0 145345.0 150556.0 126039.0 134266.0 140299.0 148556.0 True False 155736.3760569159 161717.2854749713 118831.0460337426 102679.00855834836 125166.35558732151 141141.70951965934 137256.22683010407 113518.27482574151 147714.9187139147 143355.09965692734 1.0863678824793748 1.1280888218276692 0.828927930140784 0.7162564066717986 0.8731210531530826 0.9845600879036392 0.9574561850857145 0.7918677123967662 1.0304127238404572 1.0 17.129233701783967 -5.255234315790212 24.845421474554378 0.8882524183367662 1.1072283794798625 0.434786676632982 0.09500143371045908 409.5919703146259 1640016.199365391 0.025146827548162675 0.06307192913547424 5.556044100052007e-06 5.255234315790212 0.21897596114309636 EKVIET(ph)PENDFK ddPTM_PC-9_Lapatinib_30min_R1 5 EKVIETPENDFK 12 1 A0A024QZ33;Q9H0G5 A0A024QZ33 CCDC55;NSRP1 Nuclear speckle splicing regulatory protein 1 1 EKVIET(1)PENDFK;EKVIET(1)PENDFK;EKVIET(1)PENDFK;EKVIET(1)PENDFK;EKVIET(1)PENDFK 151.73 5.2318e-05 41259400.0 230072.0 282247.0 266225.0 273061.0 284168.0 259134.0 245545.0 235560.0 250633.0 245574.0 True False 226791.13108996282 281593.4744127045 244337.00815821846 293142.81684479286 267453.79693578376 248051.44289085767 258258.1186390875 246504.97755405918 222404.07225750538 288021.13869321364 0.7874114105615349 0.9776833592503933 0.8483301234999788 1.0177822995034909 0.9285908602030172 0.8612265197488516 0.8966637650654237 0.8558572425360227 0.7721796853751056 1.0 18.1358151734958 -6.763219636780794 24.823154034628566 0.8693939102357412 0.9179549996315063 0.0387304775427082 0.07939615310933748 118.97131617190739 1658871.6830050836 0.026190840641089765 0.024295488100428055 1.7249653005576712e-07 6.763219636780794 0.04856108939576509 EKVS(ph)SIDLEIDSLSSLLDDMTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EKVSSIDLEIDSLSSLLDDMTK 22 1 Q15942;H7C3R3;C9IZ41 Q15942 ZYX Zyxin 1 EKVS(0.496)S(0.496)IDLEIDS(0.006)LS(0.002)S(0.001)LLDDMTK 58.913999999999994 0.0043209 4985900.0 1388.4 0.0 618.29 0.0 1107.4 894.99 779.05 798.96 0.0 699.04 True False 1623.4286978500309 0.0 633.0323784778825 0.0 890.4129195374155 848.0551488601507 705.2527441664331 777.9881465680949 0.0 825.7704184024046 1.9659564712802788 0.0 0.766596095440901 0.0 1.07828144444805 1.0269865933207678 0.8540542606634738 0.9421361303705298 0.0 1.0 9.68959692750829 -4.742820409293067 24.97211584356353 0.6460068602960078 1.965960804851057 0.46381324788785294 0.4306752001955866 1149.2231204182026 1541278.4001162844 0.105796288762736 3.619482071461335 1.807921588404284e-05 4.742820409293067 1.3199539445550492 EKVS(ph)SIDLEIDSLSSLLDDMTK ddPTM_PC-9_Lapatinib_30min_R1 1 EKVSSIDLEIDSLSSLLDDMTK 22 1 Q15942;H7C3R3;C9IZ41 Q15942 ZYX Zyxin 1 EKVS(0.5)S(0.5)IDLEIDSLSSLLDDMTK 73.688 0.001614 1704700.0 2166.6 3114.1 3212.7 5610.7 9647.2 9783.2 8207.2 11874.0 11374.0 11109.0 True False 2135.703886694222 3106.8894927797337 2948.5642073806325 6023.329594746519 9079.77066312495 9364.795341753079 8632.128657861987 12425.709388168158 10092.940346470205 13029.175848187957 0.1639170360104739 0.2384563328471637 0.2263047365187497 0.46229551776171773 0.6968798923983919 0.718755771728685 0.6625229990323991 0.9536834511214516 0.7746415018163937 1.0 13.669458209630779 -6.060719503978458 0.5213068767182012 0.9259749371547021 0.01582662853378698 0.9171903509653232 0.08247568892250132 0.368053707945643 0.18168894049285886 0.06403594820717712 0.17732646631730664 8.69521842525628e-07 6.060719503978458 -0.9101483086209151 down EKVSS(ph)IDLEIDSLSSLLDDMTK ddPTM_PC-9_AZD4547_30min_R2 1 EKVSSIDLEIDSLSSLLDDMTK 22 1 Q15942;H7C3R3;C9IZ41 Q15942 ZYX Zyxin 1 EKVS(0.435)S(0.565)IDLEIDSLSSLLDDMTK 83.788 0.00037553 3899400.0 15890.0 15959.0 17160.0 16032.0 14597.0 16788.0 16636.0 17313.0 15696.0 15873.0 True False 20942.689467467797 21117.43465474549 16932.44718785519 12336.070091930873 12570.458512560688 15738.24370610298 18116.571771797655 14637.673663161646 16525.65851598091 15317.291101365192 1.3672580437934765 1.3786664048490498 1.1054465881598374 0.8053689134909364 0.820671124507147 1.0274821834978556 1.182752984970232 0.9556307029940188 1.0788891068674682 1.0 13.902873555390261 -5.373607162891673 3.6753507549766016 0.9818426997628428 1.3751408351790522 0.6782134705797942 0.1060673545954215 0.14288345533952526 3.4465262880177794 0.03154194435499711 0.07304528925095183 4.230511082661552e-06 5.373607162891673 0.3932981354162094 EKYIDQEELNK ddPTM_PC-9_AZD4547_30min_R2 2 EKYIDQEELNK 11 1 P07900;P07900-2;Q14568;P08238;Q58FF8 P07900;P08238 HSP90AA1;HSP90AA2P;HSP90AB1;HSP90AB2P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 0 ; 134.08 7.5227e-05 17116100.0 87748.0 74577.0 92106.0 141486.0 114887.0 99162.0 92862.0 100910.0 97602.0 102051.0 False True 115650.03872821675 98682.55681727894 90884.61425900864 108868.5886369095 98936.92314397181 92961.38446417601 101126.53810246901 85316.67818111507 102761.04246156791 98478.22555190674 1.1743716753634938 1.002074887765565 0.92289045369836 1.1055092435588831 1.0046578580137322 0.9439790770313701 1.0268923666700958 0.8663506851689324 1.043489988631078 1.0 16.587517146139 -6.521476062705993 23.421609978854644 0.9713342193247583 1.0406044483309835 0.1703662919422969 0.07637548760022336 45.82742271045247 765251.6332072782 0.024600632831705414 0.024977722217091772 3.009705052190382e-07 6.521476062705993 0.06927022900622526 EKYIDQEELNK ddPTM_PC-9_Lapatinib_30min_R1 2 EKYIDQEELNK 11 1 P07900;P07900-2;Q14568;P08238;Q58FF8 P07900;P08238 HSP90AA1;HSP90AA2P;HSP90AB1;HSP90AB2P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 0 ; 167.71 0.00066646 37271000.0 282403.0 211317.0 241296.0 220482.0 238670.0 195098.0 231366.0 211143.0 214014.0 202513.0 False True 278375.88143363287 210827.708469778 221457.57430949574 236696.9817863909 224631.899843274 186754.11333565103 243344.9993974674 220953.47459541773 189909.48965267057 237517.10221838922 1.1720245777404077 0.8876316968364191 0.9323858039741186 0.996547109979288 0.9457504227915862 0.786276489530159 1.024536747563212 0.9302634316928396 0.7995613279167367 1.0 17.857671871658702 -4.756507983066016 24.893898122343824 0.9226443397242369 1.1720249821216058 0.4935137406183553 0.07581948090610299 122.89562252829109 620306.4009051762 0.01846266901427602 0.148405374671535 1.751830232314433e-05 4.756507983066016 0.2493806423973689 ELAEDGYSGVEVR ddPTM_PC-9_Lapatinib_30min_R1 1 ELAEDGYSGVEVR 13 0 P23396;P23396-2;E9PL09;F2Z2S8;H0YCJ7;E9PPU1;H0YF32;E9PQ96;E9PJH4;E9PK82;H0YEU2 P23396 RPS3 40S ribosomal protein S3 0 129.0 0.00045174 2208600.0 18726.0 20040.0 26260.0 18970.0 22776.0 20459.0 16606.0 22281.0 28715.0 18154.0 False True 18458.963806072188 19993.59861125394 24101.004166531406 20365.117082064902 21436.36045933888 19584.01626225837 17465.777426217974 23316.256600789533 25480.814317644792 21291.894711315534 0.8669479187430985 0.9390239282288195 1.131933277582994 0.9564727497568313 1.006785011384946 0.9197873898864662 0.8203016999203844 1.0950766438084139 1.1967377569316584 1.0 14.378016716798184 -7.940460875307368 14.4292629388144 1.1142117137906276 0.9568683066734314 0.3578083440117723 0.09023525510180608 1.6756598765266422 404.71555216964384 0.05055980205445768 0.024285766370107747 1.1469358418488953e-08 7.940460875307368 -0.1573434071171962 ELAEQELEK ddPTM_PC-9_Lapatinib_30min_R1 2 ELAEQELEK 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 112.36 0.0022172 2248500.0 31621.0 29498.0 38338.0 36557.0 31055.0 32330.0 34178.0 28930.0 33874.0 29340.0 False True 31170.07874141878 29429.69919335173 35185.99762895965 39245.52373057707 29228.405956479135 30947.321264910945 35947.56960576164 30274.193414157402 30058.753410966383 34411.37990690745 0.9058072889184534 0.8552315912052181 1.0225105103064092 1.1404809640516407 0.8493819787393085 0.8993339223429061 1.0446419092465926 0.8797727233275063 0.8735120036535542 1.0 15.070598125298746 ELAPAWEDT(ph)SPEQDNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELAPAWEDTSPEQDNR 16 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 ELAPAWEDT(0.973)S(0.027)PEQDNR;ELAPAWEDT(0.922)S(0.078)PEQDNR 151.49 7.6134e-05 5502100.0 16605.0 22082.0 20603.0 20492.5 22549.0 16219.400000000001 21972.0 16021.8 16378.0 16178.900000000001 True False 19415.898536300618 24274.155025146072 21094.253657312616 19344.371662581394 18130.6853193509 15368.826111378146 19890.653096495567 15601.244726500314 16617.497265868133 19112.00649789808 1.0159005826225498 1.2700997683218516 1.1037173757570948 1.012158072712505 0.9486542044313817 0.8041450861304591 1.0407412271800516 0.8163059555372233 0.8694794692381309 1.0 14.22219162895883 -5.966909858749954 1.9480694199241706 0.9032250151178469 1.150037468044765 0.5384216978874083 0.09016656999379018 0.23207398948778243 1.7779760965293008 0.02789349571847946 0.045950643169858106 1.0791706893864895e-06 5.966909858749954 0.246812452926918 ELAPAWEDTS(ph)PEQDNR ddPTM_PC-9_AZD4547_30min_R2 2 ELAPAWEDTSPEQDNR 16 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 ELAPAWEDT(0.043)S(0.957)PEQDNR;ELAPAWEDT(0.043)S(0.957)PEQDNR 125.67 3.0916e-05 8464500.0 30944.0 40919.0 42123.0 43304.0 45435.0 45045.0 43400.0 61314.0 37205.0 36444.0 True False 40783.548324815834 54145.266535342445 41564.42149732072 33320.931840130645 39127.13451518767 42228.329029152286 47262.51592305954 51839.33015555322 39171.580344487105 35168.106652690265 1.159674267585173 1.5396127824015364 1.181878282723564 0.9474758527434596 1.1125743817145342 1.200756396873641 1.3439027693418373 1.4740438166746646 1.1138381924092176 1.0 15.10198004615038 -7.039903156175546 20.92822006007897 1.2724329136113888 1.190297274289435 0.0 0.1825266933223883 322.2983935667841 169034.18794518703 0.07311743416714704 0.05666256453259511 9.122142323752096e-08 7.039903156175546 -0.08213563932195367 ELAPAWEDTS(ph)PEQDNR ddPTM_PC-9_Lapatinib_30min_R1 1 ELAPAWEDTSPEQDNR 16 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 ELAPAWEDT(0.052)S(0.948)PEQDNR 85.28 0.004767 3074300.0 6221.6 12719.0 12183.0 9279.1 11402.0 12540.0 10852.0 10294.0 13113.0 9568.4 True False 6132.878843098296 12689.54993695303 11181.36076773998 9961.51596817018 10731.356777194493 12003.69343216775 11413.863460756196 10772.296820094576 11636.075853988372 11222.285190908424 0.5464910879351704 1.1307456298859069 0.9963532896845646 0.8876548580533635 0.9562541491895385 1.0696300466408013 1.0170712351886206 0.959902251354439 1.0368722284312624 1.0 13.454078861013233 -4.751297883259086 24.99728921800345 1.0015724015677785 0.5464901565087967 0.8274453240544132 0.06292931960048398 173.9476339566009 428726.17110249493 0.01624010537122724 0.21825683943796462 1.7729729788200136e-05 4.751297883259086 -0.45508224505898176 ELAPYDENWFYTR ddPTM_PC-9_AZD4547_30min_R2 2 ELAPYDENWFYTR 13 0 M0R2L9;M0QYF7;M0R140;P39019 M0R2L9 RPS19 40S ribosomal protein S19 0 ; 115.92 0.0012992000000000001 15373300.0 13618.7 17511.7 16248.599999999999 17680.8 20166.6 19643.7 16020.5 17456.1 16549.5 17465.0 False True 17949.16331344264 23172.014565042064 16033.132947353355 13604.764725636935 17366.81569085471 18415.376333665423 17446.293464179158 14758.660846272516 17424.272783526125 16853.555665932276 1.0650075075685674 1.3749036122912568 0.9513204967046022 0.8072340932268414 1.0304541092156556 1.092670098743033 1.0351698958959172 0.8757001275467127 1.0338633062901672 1.0 14.040765374543993 -5.282242415726626 24.902312323811742 0.9757308686105259 1.2199555691265993 0.4564927846540964 0.10544277188681986 576.2404166646036 689788.9165728416 0.027700847127533484 0.05776453516297344 5.221046777774057e-06 5.282242415726626 0.24422470051607337 ELAPYDENWFYTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELAPYDENWFYTR 13 0 M0R2L9;M0QYF7;M0R140;P39019 M0R2L9 RPS19 40S ribosomal protein S19 0 ; 146.07 0.00046808 13414900.0 17308.4 20910.6 21873.7 18436.7 22580.1 13654.7 19448.7 10999.8 12606.9 11892.0 False True 20238.370263517336 22986.466174658948 22395.251964469197 17403.751471587875 18155.691497604108 12938.623494274461 17606.378339605573 10711.066905251477 12791.252062588403 14047.925462979792 1.4406661194815629 1.6362890189896513 1.5942035016833582 1.2388840983995553 1.2924108648959896 0.9210344636559575 1.253308069294879 0.7624660974660017 0.9105438448044819 1.0 13.778069474746442 -6.345482573324672 0.8868823144838255 0.9289832248954798 1.5914290114380236 0.7551984558279844 0.14075893684610435 0.2811006231450916 0.478665065806831 0.07196060862518543 0.10647736503265792 4.5135413619548006e-07 6.345482573324672 0.6624457865425438 ELAPYDENWFYTR ddPTM_PC-9_Lapatinib_30min_R1 2 ELAPYDENWFYTR 13 0 M0R2L9;M0QYF7;M0R140;P39019 M0R2L9 RPS19 40S ribosomal protein S19 0 ; 205.8 3.7184e-09 37687000.0 20367.8 25940.3 22361.5 18168.9 25091.8 28989.8 23954.0 24119.3 26111.8 18670.7 False True 20077.351437002922 25880.23682911727 20523.02378788621 19505.101515673647 23615.94965637686 27749.97383252444 25194.220912177832 25239.970729833625 23170.814114556062 21897.90561785606 0.9168617212703385 1.181858999703329 0.9372140032949663 0.8907290887110562 1.0784570026240257 1.2672432842114576 1.1505310759780552 1.1526203085491595 1.058129234773121 1.0 14.418505272242404 -6.517138316389204 24.94191759672586 1.140801302434553 0.9917656491155206 0.3141891977608726 0.09889992853262809 297.016023651618 1290528.386921942 0.032135314565264805 0.03313565228960084 3.0399167028371806e-07 6.517138316389204 -0.14903565331903235 ELAQQIQK ddPTM_PC-9_Lapatinib_30min_R1 2 ELAQQIQK 8 0 P60842;P60842-2;J3KT12;J3QL43;J3KTB5;J3QR64;Q14240-2;J3KS25;E7EQG2;J3QLN6;J3QKZ9;Q14240;J3KSN7 P60842 EIF4A1;EIF4A2 Eukaryotic initiation factor 4A-I;Eukaryotic initiation factor 4A-II;Eukaryotic initiation factor 4A-II, N-terminally processed 0 ; 139.88 0.012088 23737000.0 82590.0 72541.0 68661.0 79623.0 81313.0 68164.0 75088.0 66321.0 71432.0 76394.0 False True 81412.25145484906 72373.03577140588 63015.95761912454 85478.74103454176 76530.32920750875 65248.78461804481 78975.68923159438 69402.51577671403 63386.575947692945 89598.60111139348 0.9086330639652873 0.8077473852680812 0.7033140789863442 0.954018700897688 0.8541464739205292 0.7282344122418188 0.8814388645801271 0.774593742712895 0.7074505088409536 1.0 16.451188587441592 ELAS(ph)PVSPELR ddPTM_PC-9_AZD4547_30min_R2 1 ELASPVSPELR 11 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 ELAS(0.997)PVS(0.003)PELR 100.04 0.0043138000000000004 1939200.0 12319.0 16626.0 26032.0 30105.0 33861.0 29731.0 23409.0 28480.0 27169.0 20899.0 True False 16236.185748882059 22000.029360849567 25686.798670993358 23164.757367613474 29159.984633405296 27871.915870034987 25492.355650758098 24079.070405293354 28605.09787338719 20167.33237116053 0.8050735441887175 1.0908745368975923 1.273683509462348 1.1486277382297367 1.4459019218180953 1.3820328517961098 1.2640420250728053 1.1939640782499645 1.4183877841123271 1.0 14.299732643995066 -4.573427356610488 1.2619808187786217 1.2870709194416252 0.38463553922628196 0.553370057727225 0.12703527969637365 1.544517792713723 1.5311089920580463 0.03622973401288651 2.0521861512278847 2.6703773973555823e-05 4.573427356610488 -0.9024353802153433 ELAS(ph)PVSPELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELASPVSPELR 11 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 ELAS(0.997)PVS(0.003)PELR 76.24 0.020834000000000002 1935100.0 18172.0 25373.0 25262.0 21324.0 24562.0 22845.0 28558.0 17413.0 20575.0 17769.0 True False 21248.160686639847 27891.863755684775 25864.341886668517 20129.28541334077 19749.252419792316 21646.967983675935 25852.77949798474 16955.927200598566 20875.870450924194 20990.379040673382 1.0122809428770656 1.3287927627051555 1.2321998491094792 0.9589767471247633 0.9408716432192046 1.0312804710067536 1.2316490068087578 0.8077951888216408 0.9945447107206924 1.0 14.357440598354952 -5.759805703241454 24.999682896688302 0.9961228899635973 1.2048613800264047 0.3485451932637573 0.12240082610182754 46.15015376954448 706196.5262809509 0.034009979656541504 0.055160954533239416 1.7385784683991905e-06 5.759805703241454 0.20873849006280742 ELAS(ph)PVSPELR ddPTM_PC-9_Lapatinib_30min_R1 1 ELASPVSPELR 11 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 ELAS(0.984)PVS(0.016)PELR 103.46 0.0028951999999999997 2411700.0 24536.0 22295.0 27142.0 19839.0 25661.0 24412.0 20571.0 22460.0 27451.0 16726.0 True False 24186.112140648667 22243.377297300725 24910.48953114985 21298.026240963925 24151.670431467093 23367.95566715144 21636.06572532397 23503.57359426115 24359.17930815486 19617.06681400591 1.2329117482222478 1.1338788570276837 1.2698376249279337 1.0856886222030844 1.2311560469490592 1.1912053870595742 1.1029205298865865 1.1981186492916671 1.2417340237003855 1.0 14.25982172236869 -10.99108040936005 5.564896144374139 0.9997973515015189 1.1845635348573607 0.4793034285680735 0.0585552454168341 0.0001386737755700759 1.325204370222763e-05 0.05340447509109952 0.012938369228582748 1.0207504748791518e-11 10.99108040936005 0.18476618335584172 ELASALK ddPTM_PC-9_Lapatinib_30min_R1 1 ELASALK 7 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 107.59 0.045542 26760000.0 98470.0 98157.0 109850.0 83481.0 89065.0 82312.0 88230.0 84863.0 114800.0 99945.0 False True 97065.79974281341 97929.72349724831 100818.55703326229 89620.47122445244 83826.37180852715 78791.70763864365 92798.11768729454 88806.04478761298 101870.01510240708 117220.36008165858 0.8280626307170101 0.8354327134725407 0.8600771825221285 0.7645469708676942 0.7151178494088539 0.6721674253837423 0.7916552860155786 0.7575991468184239 0.8690471094905521 1.0 16.838863648614648 -8.56940595365402 2.9051014531529784 0.9997184033799397 0.7772872360684994 0.6234341263583554 0.05357136796551636 0.2111232176588992 4.505247612412083 0.05882535133850144 0.015718702619421057 2.6952189180472287e-09 8.56940595365402 -0.2224311673114403 ELASPVS(ph)PELR ddPTM_PC-9_AZD4547_30min_R2 1 ELASPVSPELR 11 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 ELAS(0.319)PVS(0.681)PELR 110.64 0.0019117000000000001 2801100.0 12293.0 17064.0 17175.0 13276.0 15325.0 18375.0 16257.0 18564.0 18888.0 13967.0 True False 16201.918289715646 22579.60429529276 16947.248278054358 10215.423312155339 13197.3882787554 17226.0083452253 17703.841506017954 15695.3603582818 19886.38111938376 13478.019581223938 1.202099328619936 1.6752909549670136 1.2573989951508424 0.7579320723340036 0.9791785951357808 1.278081563943017 1.3135343363561331 1.1645153253929688 1.4754675937025075 1.0 13.718320906466362 -1.5228787926290883 0.01583155845762337 1.8182192245700782e-07 2.6867120286193806 0.03966243813121684 0.24172535194715336 23788.12227786796 29.176868689127552 1955.6971692399889 3121.4328695565873 0.029999996729264348 1.5228787926290883 2.6867118467974582 ELASPVS(ph)PELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELASPVSPELR 11 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 ELAS(0.006)PVS(0.994)PELR 92.906 0.0073917 2290700.0 18765.0 20867.0 17063.0 13289.0 16565.0 12823.0 16697.0 12195.0 11124.0 9008.0 True False 21941.54387435597 22938.53785480132 17469.84663178785 12544.460413519297 13319.207162847462 12150.539306398627 15115.339284188349 11874.894171670563 11286.667455459581 10641.079092711236 2.0619660546819123 2.1556589942568336 1.6417363765065967 1.1788710810458884 1.2516782411635912 1.141852175003691 1.420470532405104 1.1159483045102492 1.0606694449992906 1.0 13.377356838919027 -5.51925052850886 2.4497579159838696 1.18093151129737 2.1183535350612934 0.9176543216274943 0.11338926553462464 0.07420321673330207 0.8812044207473263 0.032467403538820445 0.07590401643880341 3.0251678166430894e-06 5.51925052850886 0.9374220237639235 ELASPVS(ph)PELR ddPTM_PC-9_Lapatinib_30min_R1 2 ELASPVSPELR 11 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 ELAS(0.006)PVS(0.994)PELR;ELAS(0.006)PVS(0.994)PELR 100.73 0.0040278 5002300.0 27918.0 40328.0 32878.0 27090.0 32341.0 31850.0 33282.0 38969.0 35074.0 25344.0 True False 27519.884200465844 40234.622993744946 30174.89775275016 29082.288969590845 30438.765964852413 30487.849745976313 35005.1791099233 40779.642003328714 31123.596774406167 29724.676631242757 0.9258261928925572 1.353576474283844 1.0151463757568413 0.9783887417978934 1.0240234517087765 1.0256747322839304 1.1776470958520153 1.3719120483371852 1.0470625857605813 1.0 14.859373494817604 -7.274100678298247 22.435085348490748 1.1801481592482554 1.060865594852891 0.0803985178986314 0.1422492515401816 415.76127913730835 736696.3855670433 0.05851006685405714 0.03983483037204122 5.3198492004139194e-08 7.274100678298247 -0.11928256439536455 ELDEEGS(ph)DPPLPGR ddPTM_PC-9_AZD4547_30min_R2 5 ELDEEGSDPPLPGR 14 0 C9JQV0;Q9BRJ6;H7C0T1;H7C2R9 C9JQV0 C7orf50 Uncharacterized protein C7orf50 1 ELDEEGS(1)DPPLPGR;ELDEEGS(1)DPPLPGR;ELDEEGS(1)DPPLPGR;ELDEEGS(1)DPPLPGR;ELDEEGS(1)DPPLPGR 150.11 1.8925999999999998e-05 150431100.0 235663.6 251316.6 299473.9 440714.0 342331.0 315426.8 246117.8 333622.6 247659.1 340622.0 True False 310599.72269260883 332549.77618602704 295502.6804132296 339114.1962634245 294804.2497131882 295703.11233239254 268021.80740664504 282068.89305467054 260749.85441992682 328696.9274572672 0.9449425800701738 1.0117215842525962 0.8990126031879229 1.0316926260514305 0.8968877561276102 0.8996223804703375 0.8154070969875119 0.8581427737603097 0.7932835163292667 1.0 18.3263984451146 -6.606088767358512 2.3730929882311798 0.8581252178610089 0.9692783180362041 0.3376576683936414 0.06297716091264562 0.29286082872244784 3.352761069327934 0.02154723579190641 0.021932759297864833 2.4769157381932465e-07 6.606088767358512 0.1111531001751952 ELDEEGS(ph)DPPLPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ELDEEGSDPPLPGR 14 0 C9JQV0;Q9BRJ6;H7C0T1;H7C2R9 C9JQV0 C7orf50 Uncharacterized protein C7orf50 1 ELDEEGS(1)DPPLPGR;ELDEEGS(1)DPPLPGR;ELDEEGS(1)DPPLPGR;ELDEEGS(1)DPPLPGR 156.6 1.1015e-05 104327600.0 195608.0 194276.0 228509.0 217764.0 285102.0 221618.0 219481.0 244752.0 218387.0 164165.0 True False 228720.57096589525 213562.43735464482 233957.52118520858 205563.3890804137 229238.3097218313 209995.9619438081 198690.1707751663 238327.51933617974 221580.496727387 193926.81497057457 1.1794169413889466 1.1012527452020993 1.206421717495376 1.060004977195159 1.1820867050109325 1.0828619135299662 1.0245626465082434 1.2289559820406595 1.142598545544145 1.0 17.565152778398954 -5.76021931025917 24.999974199625807 1.1117366526445531 1.1562526815878857 0.12044181934963183 0.07022448230326951 91.47292725303122 1874239.368143076 0.01916527298813769 0.03092960873270135 1.7369234946967013e-06 5.76021931025917 0.04451602894333262 ELDEEGS(ph)DPPLPGR ddPTM_PC-9_Lapatinib_30min_R1 4 ELDEEGSDPPLPGR 14 0 C9JQV0;Q9BRJ6;H7C0T1;H7C2R9 C9JQV0 C7orf50 Uncharacterized protein C7orf50 1 ELDEEGS(1)DPPLPGR;ELDEEGS(1)DPPLPGR;ELDEEGS(1)DPPLPGR;ELDEEGS(1)DPPLPGR 168.0 1.1612999999999999e-05 134135400.0 273567.0 240999.0 275465.0 218788.0 241927.0 224957.0 224059.0 223054.0 254069.0 190451.0 True False 269665.88441395684 240440.9816224349 252817.33102565026 234878.39937537193 227697.32950678238 215336.11351037948 235659.67869089294 233417.9031386615 225453.0737548215 223370.2015899937 1.2072598873727167 1.0764237123435803 1.1318310554677662 1.0515207386816172 1.0193720016635492 0.96403240887806 1.0550184268690286 1.0449822826730972 1.0093247539286865 1.0 17.76907721224672 -1.5228841852286614 0.46110992058514855 1.0125932345905908 5.540850729229601 0.7362846287776146 0.03418122065945845 49.78478574821087 0.5845581416581686 0.021594450498894108 213.7235155634768 0.029999624224035962 1.5228841852286614 4.528257494639011 ELDGERER ddPTM_PC-9_AZD4547_30min_R2 2 ELDGERER 8 1 A0A2R8YGX3;A0A2R8Y5V9;P67936;A0A2R8YH90;A0A590UJB9;A0A590UK79;A0A5F9UKJ4 A0A2R8YGX3 TPM4 Tropomyosin alpha-4 chain 0 ; 127.02 0.0046341 20237000.0 47291.0 39803.0 62093.0 113845.0 93657.0 57548.0 52312.0 69555.0 53462.0 67405.0 False True 62328.55428609309 52668.54135991193 61269.60624915451 87599.79413771654 80654.3421874973 53949.51446264078 56967.6666582279 58806.87296489387 56287.8921751638 65045.17146648523 0.958234913996777 0.8097225385446111 0.9419547195862786 1.3467532203040262 1.239974318909356 0.8294161310719039 0.8758169956947642 0.9040928271700279 0.8653661894667515 1.0 15.989154344103445 -6.795896538614019 24.999678291630868 0.8877490988671811 1.0549086593075572 0.23517443805617533 0.14783667875942255 319.32645740556825 231678.55887848075 0.059413311890028894 0.05239994054557102 1.5999391345498936e-07 6.795896538614019 0.16715956044037605 ELDGERER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELDGERER 8 1 A0A2R8YGX3;A0A2R8Y5V9;P67936;A0A2R8YH90;A0A590UJB9;A0A590UK79;A0A5F9UKJ4 A0A2R8YGX3 TPM4 Tropomyosin alpha-4 chain 0 ; 93.162 0.009632799999999999 17173000.0 52320.0 31676.0 53369.0 69775.0 77013.0 80477.0 65974.0 76068.0 77901.0 57233.0 False True 61176.742632896574 34820.58394060895 54641.51936305962 65865.73296360225 61922.8554924462 76256.64444833831 59724.465109603065 74071.29560070818 79040.15475078707 67608.88984382134 0.9048624045479341 0.5150296657887091 0.8082002158190033 0.974217046245755 0.9158981257566859 1.127908543158948 0.883381834068988 1.0955851482225962 1.169079316837953 1.0 16.04492533745279 -5.740171545212184 2.4177555517688942 1.029950986406657 0.6997413384577508 0.5405971715770173 0.12120046888523005 0.20460721758111045 2.436230656029378 0.034845914737747764 0.06555354852647044 1.8189822233529634e-06 5.740171545212184 -0.33020964794890617 ELDGERER ddPTM_PC-9_Lapatinib_30min_R1 2 ELDGERER 8 1 A0A2R8YGX3;A0A2R8Y5V9;P67936;A0A2R8YH90;A0A590UJB9;A0A590UK79;A0A5F9UKJ4 A0A2R8YGX3 TPM4 Tropomyosin alpha-4 chain 0 ; 106.36 0.006402600000000001 7720400.0 43189.3 29226.0 42541.4 37726.2 31955.4 31734.3 25260.2 25519.4 34398.4 25116.5 False True 42573.41266205239 29158.328992640098 39043.8103065529 40500.71059891389 30075.846198733638 30377.097965266443 26568.04955689217 26705.124487149948 30524.089960789584 29457.85355936745 1.4452313226506028 0.9898320980473438 1.3254126010188263 1.374869710628827 1.0209788753997546 1.031205410266787 0.9019003880696413 0.906553643948639 1.036195318822986 1.0 14.846364692066045 -6.38830373724582 5.07568384882875 0.9708973863142645 1.2647399880562473 0.604008095652798 0.11928035464242749 0.16583749446586166 6.162552572598005 0.03744150776813393 0.04248918934328425 4.0897453072836777e-07 6.38830373724582 0.29384260174198285 ELDPSLVSANDS(ph)PSGMQTR ddPTM_PC-9_AZD4547_30min_R2 3 ELDPSLVSANDSPSGMQTR 19 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 ELDPSLVSANDS(0.999)PS(0.001)GMQTR;ELDPSLVS(0.17)ANDS(0.762)PS(0.067)GMQT(0.001)R;ELDPSLVSANDS(0.846)PS(0.148)GMQT(0.006)R 139.19 3.4256e-05 33908600.0 85531.0 88437.0 121145.0 164391.0 130766.0 101454.0 106366.0 137998.0 94545.0 117604.0 True False 112728.07884468144 117022.53077020665 119538.5381452633 126493.19476563182 112611.39808546356 95110.06534184983 115832.36794175474 116673.57997856972 99542.45568255697 113486.71975587161 0.9933151569379912 1.031156165425709 1.053326225327599 1.114607903354148 0.9922870123280414 0.8380722039234815 1.0206689222397916 1.028081349338086 0.8771286710611513 1.0 16.79216395729822 -6.516376399482689 24.99761712937708 0.9539423879503407 1.0480371104677966 0.34030111375238603 0.0625585085784361 358.01806250124287 1376370.2403302374 0.02056655243087097 0.021281500497761105 3.0452545483076003e-07 6.516376399482689 0.09409472251745588 ELDPSLVSANDS(ph)PSGMQTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ELDPSLVSANDSPSGMQTR 19 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 ELDPS(0.017)LVS(0.037)ANDS(0.864)PS(0.081)GMQTR;ELDPSLVS(0.001)ANDS(0.639)PS(0.36)GMQTR;ELDPS(0.107)LVS(0.299)ANDS(0.563)PS(0.015)GMQT(0.015)R 126.04 2.6479000000000002e-05 33443700.0 57047.0 56308.0 68880.0 77048.0 76037.0 81796.0 80683.0 78844.0 72584.0 56511.0 True False 66703.93037039081 61897.88611339209 70522.36042885462 72731.25035298619 61138.0956861716 77506.47376637149 73040.12214566518 76774.42854212347 73645.40368456297 66755.99695917025 0.9992200462707299 0.9272258513531074 1.05641985201701 1.0895088631133854 0.915844245777129 1.1610413640257147 1.0941357401993181 1.1500753795809648 1.103202813817708 1.0 16.026609825257978 -6.7733537161858 24.99967421362033 1.110598561088365 1.002100609236242 0.397288221833238 0.06348713485298338 222.99186362576884 467897.4112019878 0.021961774673029573 0.019513934861318052 1.6851799519189678e-07 6.7733537161858 -0.10849795185212319 ELDPSLVSANDS(ph)PSGMQTR ddPTM_PC-9_Lapatinib_30min_R1 5 ELDPSLVSANDSPSGMQTR 19 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 ELDPSLVS(0.003)ANDS(0.761)PS(0.236)GMQTR;ELDPS(0.001)LVS(0.08)ANDS(0.915)PS(0.004)GMQTR;ELDPSLVS(0.045)ANDS(0.891)PS(0.064)GMQTR;ELDPSLVS(0.004)ANDS(0.976)PS(0.019)GMQTR;ELDPSLVS(0.004)ANDS(0.899)PS(0.097)GMQTR 263.19 3.0235999999999995e-78 42998000.0 152244.0 142573.0 153536.0 106925.0 111091.0 125665.0 118077.0 114129.0 144534.0 81123.6 True False 150072.9726418701 142242.88097815932 140912.86274609936 114788.6211913436 104556.84579330946 120290.60088942264 124190.44930480186 119431.8499883983 128255.05890950616 95145.70616959773 1.5772963245904572 1.4950005281857977 1.481021776168453 1.2064508826781133 1.0989129200106658 1.2642777665132254 1.3052659368929558 1.2552521264124141 1.347985779630358 1.0 16.537850930135917 -5.713204386489886 4.848387867274595 1.2227594480782686 1.5230762989293103 0.6756111777971843 0.09738906449555781 0.12058540954292511 6.094984007924971 0.026971158377563233 0.04664339962742109 1.9355108647060104e-06 5.713204386489886 0.30031685085104165 ELDPSLVSANDSPS(ph)GMQTR ddPTM_PC-9_AZD4547_30min_R2 2 ELDPSLVSANDSPSGMQTR 19 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 ELDPSLVS(0.001)ANDS(0.351)PS(0.648)GMQTR;ELDPSLVS(0.004)ANDS(0.351)PS(0.642)GMQT(0.004)R 129.43 3.2136e-05 35546600.0 88497.0 85267.0 128510.0 187510.0 151373.0 106482.0 111684.0 148255.0 100312.0 135214.0 True False 116637.2051480487 112827.89026293534 126805.87343305771 144282.46650062106 130357.47183817557 99823.6637070086 121623.65963942363 125345.59631098216 105614.28752899315 130480.19901593849 0.8939073210165871 0.8647127388972876 0.9718399756392773 1.1057805520590644 0.99905941914031 0.7650483710161639 0.9321234988656554 0.9606484145205119 0.809427701103461 1.0 16.993471362082758 ELDPSLVSANDSPS(ph)GMQTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ELDPSLVSANDSPSGMQTR 19 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 ELDPSLVS(0.001)ANDS(0.135)PS(0.864)GMQTR;ELDPSLVSANDS(0.202)PS(0.798)GMQTR;ELDPSLVS(0.039)ANDS(0.359)PS(0.597)GMQT(0.004)R 175.39 1.1033e-08 37078600.0 56650.0 58805.0 56687.0 60157.0 76835.0 68929.0 75120.0 75858.0 68294.0 51833.0 True False 66239.72611149838 64642.771771294 58038.633066644645 56786.59832162547 61779.733314662524 65314.241897430526 68004.08977829722 73866.80787819484 69292.67055044544 61229.91259019773 1.0818197072210531 1.055738429743286 0.9478803841365605 0.9274322944357168 1.0089796098215043 1.0667048038198026 1.1106350948667525 1.2063843430999792 1.1316800501449429 1.0 15.901949003098885 -7.011147247460164 2.412065956062908 1.1295823037030006 0.9997087064175766 0.37832223251073005 0.06387247674451721 0.2861208331976517 3.3347296222865705 0.028076798621643414 0.022117859095562086 9.746591237026541e-08 7.011147247460164 -0.12987359728542403 ELDPSLVSANDSPS(ph)GMQTR ddPTM_PC-9_Lapatinib_30min_R1 1 ELDPSLVSANDSPSGMQTR 19 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 ELDPSLVSANDS(0.099)PS(0.899)GMQT(0.001)R 94.61 0.00066408 16488000.0 37111.0 38171.0 38919.0 33575.0 26071.0 33870.0 28915.0 26647.0 34209.0 23220.0 True False 36581.79033467611 38082.61739471927 35719.2300516845 36044.21750291665 24537.5550375581 32421.459054826286 30412.077217818412 27885.11689965613 30356.022183259985 27233.546061294855 1.343262102274197 1.398371600562273 1.3115893894717499 1.323522739998365 0.9010047748585933 1.1904971531013602 1.1167138186620869 1.0239253028927917 1.1146555103377773 1.0 14.733097226490923 -6.1487074023178545 7.17016019010009 1.0690024734391437 1.3490628979372727 0.7714017200059237 0.07629767760062442 0.12357035624350281 7.027753967268774 0.022014789472427937 0.02852701577418861 7.100559936256212e-07 6.1487074023178545 0.28006042449812907 ELDQDMVT(ph)EDEDDPGSHKR ddPTM_PC-9_Lapatinib_30min_R1 1 ELDQDMVTEDEDDPGSHKR 19 1 Q9NRL2;Q9NRL2-2;A0A087WWN7 Q9NRL2 BAZ1A Bromodomain adjacent to zinc finger domain protein 1A 1 ELDQDMVT(1)EDEDDPGSHKR 70.15 0.0061375 4370100.0 16994.0 25703.0 16487.0 14894.0 18069.0 19419.0 23139.0 18472.0 23222.0 18228.0 True False 16751.66244368207 25643.486282687627 15131.50250166044 15989.354444927505 17006.21694502081 18588.49463789996 24337.024200003467 19330.27655535139 20606.493821499113 21378.685512716736 0.783568401982322 1.1994884469128866 0.7077845124135312 0.7479110179817425 0.7954753314886904 0.869487257616607 1.1383779505773175 0.9041845226570695 0.9638803007435467 1.0 14.383885529961233 -7.0341996713763395 24.429619054458634 0.9950984823807599 0.8511414681027845 0.22410449922232023 0.13784453274338618 821.9989786222586 587170.2333858386 0.05416009549932494 0.04197956102175217 9.242731321124891e-08 7.0341996713763395 -0.14395701427797547 ELDRYS(ph)LDSEDLYSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELDRYSLDSEDLYSR 15 1 Q9UPX8;Q9UPX8-3;H7C1X5;E7EUA2;A6NHU9;A0A0A0MSQ6;A0A590UJ45;Q9UPX8-4;A0A590UJF3 Q9UPX8 SHANK2 SH3 and multiple ankyrin repeat domains protein 2 1 ELDRYS(0.998)LDS(0.002)EDLYSR 84.195 0.029837 3894800.0 7118.0 11049.0 8700.7 9478.3 12615.0 9658.6 9087.0 9834.7 7593.7 6620.4 True False 8322.936813091701 12145.871699702873 8908.157685588498 8947.261580063212 10143.181307535218 9152.086013006463 8226.213575817188 9576.549545725995 7704.743496631014 7820.626112942437 1.0642289623484218 1.553056177893806 1.1390593997130605 1.1440594973919407 1.296978165309445 1.1702497831804768 1.0518612521577446 1.2245246617630348 0.9851824374880103 1.0 12.933068397805686 -7.501107040695222 0.4308214972437648 0.9888888660518924 1.2868452593895816 0.2768023756520136 0.1358420324147885 1.3735618875317372 0.6181062903686602 0.14287059538285793 0.13265923648089 3.154227104231327e-08 7.501107040695222 0.2979563933376892 ELDRYS(ph)LDSEDLYSR ddPTM_PC-9_Lapatinib_30min_R1 2 ELDRYSLDSEDLYSR 15 1 Q9UPX8;Q9UPX8-3;H7C1X5;E7EUA2;A6NHU9;A0A0A0MSQ6;A0A590UJ45;Q9UPX8-4;A0A590UJF3 Q9UPX8 SHANK2 SH3 and multiple ankyrin repeat domains protein 2 1 ELDRYS(0.871)LDS(0.112)EDLY(0.002)S(0.015)R;ELDRYS(0.889)LDS(0.111)EDLYSR 175.8 0.00028175 8568300.0 28692.0 27211.9 32009.0 24403.6 30616.0 27631.5 19287.5 23882.6 34467.0 26694.6 True False 28282.846818531612 27148.89251744417 29377.343578313146 26198.322152023127 28815.22707337193 26449.7651571725 20286.112375537698 24992.27278371779 30584.963506399556 31308.726041681377 0.9033534862095186 0.8671350115396196 0.9383116879046124 0.8367738156175771 0.9203576994800157 0.8448048995018153 0.6479379693868972 0.7982526261351396 0.9768830410308528 1.0 14.934277185670842 -6.971210041263602 13.237416769537791 0.825739601853601 0.8902731091636203 0.0039824396568094445 0.0961048531855274 3.488303848767981 1599.1291323636383 0.03404614574161018 0.029992458581522538 1.0685379687934192e-07 6.971210041263602 0.06453350731001939 ELDRYSLDS(ph)EDLYSR ddPTM_PC-9_AZD4547_30min_R2 1 ELDRYSLDSEDLYSR 15 1 Q9UPX8;Q9UPX8-3;H7C1X5;E7EUA2;A6NHU9;A0A0A0MSQ6;A0A590UJ45;Q9UPX8-4;A0A590UJF3 Q9UPX8 SHANK2 SH3 and multiple ankyrin repeat domains protein 2 1 ELDRYS(0.011)LDS(0.965)EDLY(0.004)S(0.02)R 89.506 0.02178 3672000.0 5059.0 5425.5 9889.3 13843.0 13451.0 13833.0 10440.0 17410.0 10904.0 13125.0 True False 6667.656766263029 7179.186773564862 9758.161420446162 10651.71022221801 11583.560831160765 12968.020323238172 11369.139775040128 14719.68454199991 11480.36317904281 12665.497744939086 0.5264425370828643 0.5668302121354482 0.7704522646451344 0.8410021016721785 0.9145760446555964 1.0238855656833517 0.8976465042270478 1.1621876090800807 0.906428109675371 1.0 13.628616154589976 -5.426773366050013 0.761851806729928 1.0119966201561466 0.4077827245066113 0.855112994999477 0.07120181931374561 0.42885958166432425 0.341816713183145 0.030049683338533875 0.19080409825246325 3.743058665689398e-06 5.426773366050013 -0.6042138956495353 ELDRYSLDSEDLY(ph)SR ddPTM_PC-9_AZD4547_30min_R2 1 ELDRYSLDSEDLYSR 15 1 Q9UPX8;Q9UPX8-3;H7C1X5;E7EUA2;A6NHU9;A0A0A0MSQ6;A0A590UJ45;Q9UPX8-4;A0A590UJF3 Q9UPX8 SHANK2 SH3 and multiple ankyrin repeat domains protein 2 1 ELDRY(0.001)S(0.1)LDS(0.327)EDLY(0.568)S(0.005)R 103.43 0.0069078 4515900.0 9911.1 11129.0 13076.0 18466.0 21157.0 16692.0 12705.0 14547.0 16220.0 16897.0 True False 13062.623636313405 14726.23161054342 12902.603696293385 14208.948996856016 18219.715746403122 15648.24660127894 13835.72038715373 12299.095406804856 17077.356086213702 16305.441173046516 0.8011205276620417 0.9031483082399766 0.7913066294472213 0.8714237686707872 1.1174009677530818 0.9596947690778251 0.8485339489019577 0.7542939363784713 1.047340940056451 1.0 13.993065855873839 -6.012999676988399 24.884127300864854 0.9424155018279785 0.837717072211156 0.2401246602474646 0.09860109566566876 1042.7680460509403 1996082.6172691747 0.03028295773270606 0.04108879935308233 9.705106890738979e-07 6.012999676988399 -0.10469842961682252 ELEAGSLVYVHR ddPTM_PC-9_AZD4547_30min_R2 1 ELEAGSLVYVHR 12 0 Q6UVK1 Q6UVK1 CSPG4 Chondroitin sulfate proteoglycan 4 0 72.34 0.021202000000000002 4645600.0 61267.0 49717.0 56296.0 72958.0 63598.0 58219.0 60564.0 63932.0 55534.0 63200.0 False True 80748.63156723419 65787.04798107545 55549.47825684707 56138.660289863554 54768.515481388946 54578.55672656715 65954.07867198555 54052.778411208354 58469.41386509196 60987.38723658284 1.3240218219874438 1.0786992353988492 0.910835514913256 0.9204962342802117 0.8980301987512666 0.8949154767828551 1.08143800973365 0.8862943775821435 0.9587132112788643 1.0 15.896223290213593 -4.840123369769585 2.4096152029971423 0.9407480044039715 1.3855386972904289 0.8057512163173768 0.057116549202684476 0.1939989930819548 1.5562642023201732 0.014986178015061259 0.17354985079741997 1.4450292238632035e-05 4.840123369769585 0.44479069288645734 ELEAIFGRPVVDGEEGEPHS(ph)ISPR ddPTM_PC-9_AZD4547_30min_R2 5 ELEAIFGRPVVDGEEGEPHSISPR 24 1 P36507;G5E9C7 P36507 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 1 ELEAIFGRPVVDGEEGEPHS(0.791)IS(0.209)PR;ELEAIFGRPVVDGEEGEPHS(0.69)IS(0.31)PR;ELEAIFGRPVVDGEEGEPHS(0.664)IS(0.336)PR;ELEAIFGRPVVDGEEGEPHS(0.5)IS(0.5)PR;ELEAIFGRPVVDGEEGEPHS(0.5)IS(0.5)PR 79.373 7.4923e-05 84378900.0 62536.2 67815.09999999999 83237.90000000001 77965.8 83301.09999999999 89812.7 77056.6 100135.4 82689.5 70041.2 True False 82421.41076623405 89735.0048784404 82134.11105932234 59991.98936960238 71736.18014665126 84196.697671141 83914.48812158607 84661.7748125778 87060.29815603993 67589.07890688209 1.2194486461309313 1.327655389446406 1.2151979637491293 0.8875988597544543 1.061357564074555 1.2457145301112822 1.2415391580819677 1.2525954811311584 1.288082328744019 1.0 16.044502533161477 -6.793483773785927 24.998626050696668 1.2236205997895004 1.1424569865684175 0.04635220949253949 0.13147527116413715 592.9945317839607 462605.70137749804 0.050132464370251185 0.044215888268037434 1.6088524870964428e-07 6.793483773785927 -0.0811636132210829 ELEAIFGRPVVDGEEGEPHS(ph)ISPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ELEAIFGRPVVDGEEGEPHSISPR 24 1 P36507;G5E9C7 P36507 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 1 ELEAIFGRPVVDGEEGEPHS(0.5)IS(0.5)PR;ELEAIFGRPVVDGEEGEPHS(0.789)IS(0.211)PR;ELEAIFGRPVVDGEEGEPHS(0.787)IS(0.213)PR;ELEAIFGRPVVDGEEGEPHS(0.5)IS(0.5)PR;ELEAIFGRPVVDGEEGEPHS(0.633)IS(0.367)PR 78.257 8.0801e-05 48255500.0 53883.3 60319.5 62597.4 56485.2 71107.3 60378.3 70421.3 56456.899999999994 59711.7 53404.399999999994 True False 63004.678446314196 66307.62132231217 64089.95941796146 53320.5173714892 57174.33501302413 57211.955658077524 63750.48465793935 54974.96619603015 60584.87064906203 63086.19497100222 0.9987078547893798 1.0510638873178306 1.015910999980592 0.8452010363915299 0.9062891657882441 0.9068855029911883 1.0105298740436393 0.8714262481878893 0.960350686499797 1.0 15.945036717152613 -5.62083280597291 9.45895002706553 0.9249621156327916 1.0269905161135076 0.41649067620818614 0.050489576899166805 0.2528169010093879 22.052818896742576 0.013326367855106132 0.02310545006449472 2.394237308831625e-06 5.62083280597291 0.10202840048071593 ELEAIFGRPVVDGEEGEPHS(ph)ISPR ddPTM_PC-9_Lapatinib_30min_R1 4 ELEAIFGRPVVDGEEGEPHSISPR 24 1 P36507;G5E9C7 P36507 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 1 ELEAIFGRPVVDGEEGEPHS(0.537)IS(0.463)PR;ELEAIFGRPVVDGEEGEPHS(0.5)IS(0.5)PR;ELEAIFGRPVVDGEEGEPHS(0.69)IS(0.31)PR;ELEAIFGRPVVDGEEGEPHS(0.783)IS(0.217)PR 69.292 0.00036314 68855500.0 46764.9 56114.3 54593.2 50405.3 61864.0 62378.6 58081.2 56857.8 74866.0 55827.2 True False 46098.02395036765 55984.3707860023 50104.75783184625 54112.27390915161 58225.28114930365 59710.81268961875 61088.36034250575 59499.62095760386 66433.80270606982 65476.85713493195 0.704035379330605 0.8550253209409863 0.7652285101068989 0.8264335870250967 0.889249785299185 0.9119376723682571 0.932976367766361 0.908712231483401 1.0146150199171264 1.0 15.998697454191907 -6.036501523554305 0.33350400620940973 1.0123722606225336 0.6719335128518532 0.8261431240654296 0.03841481648608055 1.2170121164859604 0.2026517743891334 0.04242655015882921 0.15731489711513882 9.193872494835652e-07 6.036501523554305 -0.3404387477706804 ELEAIFGRPVVDGEEGEPHSIS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 ELEAIFGRPVVDGEEGEPHSISPR 24 1 P36507;G5E9C7 P36507 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 1 ELEAIFGRPVVDGEEGEPHS(0.272)IS(0.728)PR;ELEAIFGRPVVDGEEGEPHS(0.404)IS(0.596)PR 82.538 3.0849e-05 66461000.0 22015.3 25952.9 26958.0 26167.0 27076.5 31373.3 27613.0 32355.0 34054.0 25963.9 True False 29015.70745331303 34341.66738837922 26600.519305955706 20134.602426119956 23317.39534941079 29411.522591415327 30070.503506530964 27355.27819393492 35854.024917381095 25054.91176379609 1.158084599413366 1.370656089797224 1.0616888040449215 0.803618971638691 0.9306516650002342 1.173882505302392 1.2001839715110199 1.0918129926708748 1.431017808220324 1.0 14.612805836568269 -6.964710160060463 24.873410562715712 1.1882089872966382 1.0657298431188948 0.10021279495350544 0.17096441282590494 437.4679959617801 308340.1812272681 0.06537598475683254 0.05765598143543696 1.084650547826473e-07 6.964710160060463 -0.1224791441777433 ELEAIFGRPVVDGEEGEPHSIS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ELEAIFGRPVVDGEEGEPHSISPR 24 1 P36507;G5E9C7 P36507 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 1 ELEAIFGRPVVDGEEGEPHS(0.139)IS(0.861)PR;ELEAIFGRPVVDGEEGEPHS(0.216)IS(0.784)PR;ELEAIFGRPVVDGEEGEPHS(0.25)IS(0.75)PR;ELEAIFGRPVVDGEEGEPHS(0.169)IS(0.831)PR;ELEAIFGRPVVDGEEGEPHS(0.398)IS(0.602)PR 94.588 3.0501e-06 71480100.0 86811.6 94593.1 97140.7 98814.5 106195.4 97978.6 124142.0 87818.4 92570.7 90565.20000000001 True False 101507.08927274414 103983.67782398073 99456.9026961565 93278.24392593157 85387.17370005733 92840.4297345324 112382.37104975207 85513.26005128617 93924.37136094137 106983.95384627103 0.9488066726212345 0.9719558315576792 0.9296431765745878 0.8718900411922177 0.7981306600684541 0.8677977060741094 1.0504600644245978 0.7993092139234558 0.8779295210560695 1.0 16.707034902442714 -5.55753636192049 4.338854021546326 0.888258752639645 0.9590298699732226 0.10600079935266227 0.07478729090681446 0.4127873534049592 17.58682964420123 0.02080276259987651 0.03919114564443186 2.7698971158964134e-06 5.55753636192049 0.07077111733357755 ELEAIFGRPVVDGEEGEPHSIS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 ELEAIFGRPVVDGEEGEPHSISPR 24 1 P36507;G5E9C7 P36507 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 1 ELEAIFGRPVVDGEEGEPHS(0.456)IS(0.544)PR 65.149 0.00056464 7388400.0 22465.0 24898.0 26191.0 21371.0 30602.0 30860.0 30187.0 31163.0 34457.0 26070.0 True False 22144.644980423545 24840.350210728557 24037.67708018368 22942.694631566115 28802.050525846844 29540.189738173598 31749.9351538746 32610.94674612469 30576.089811704212 30576.16476390854 0.7242453444181665 0.8124089598068095 0.7861573636127591 0.7503457287307396 0.941977214874384 0.9661182154879744 1.0383884113337705 1.0665479793796102 0.999997548672147 1.0 14.900119837160911 -6.48741965284257 1.8705427946674267 1.025979865437724 0.7691391771283415 0.9188528510092226 0.034443554713774846 0.08800440032431793 0.6178543560821571 0.01278977260853438 0.014258262482105348 3.2552200150528313e-07 6.48741965284257 -0.25684068830938245 ELEDATETADAMNR ddPTM_PC-9_AZD4547_30min_R2 3 ELEDATETADAMNR 14 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ;; 138.76 0.00021929 22729000.0 36081.2 34199.9 47915.0 64635.0 54684.0 53561.7 43131.8 64904.0 43650.0 57424.3 False True 47554.27106441782 45254.34885950437 47279.61579289515 49734.39935079542 47092.07051454879 50212.478431806965 46970.44664263179 54874.57814554633 45957.24988675882 55413.89273559658 0.858165140848697 0.8166607077295986 0.8532087073991796 0.8975077709862317 0.8498242622882538 0.9061351937751821 0.8476294359385274 0.990267520229565 0.8293452709781741 1.0 15.757960097124752 -14.522878744964391 0.08667279201600003 1.4126920030410133 0.7631076852554929 0.44742065592248714 0.0452420590324855 189.9008532713488 1.1467977329748116 14.606530447433546 1.119271655640363 3.0000000021824814e-15 14.522878744964391 -0.6495843177855204 ELEDATETADAMNR ddPTM_PC-9_Lapatinib_30min_R1 5 ELEDATETADAMNR 14 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ;;;; 241.39 6.228000000000001e-27 39230000.0 74684.7 68197.0 72022.8 63064.5 76107.8 73533.7 71498.8 67467.7 78252.4 58389.9 False True 73619.68248250351 68039.09403651103 66101.36340004798 67702.47370700481 71631.28883769183 70388.83506642687 75200.65801768475 70602.49564494798 69438.790677697 68482.51641534879 1.0750142713214224 0.9935250279626352 0.9652297675386367 0.9886096079820872 1.0459792161147472 1.0278365742216042 1.0981000984483427 1.0309565030692134 1.0139637722502541 1.0 16.06344809462442 -6.268640231373991 24.20901028486344 1.040370085083286 1.0018493441645493 0.13882705122549954 0.035882647306186614 601.5426990639653 2022361.3954406916 0.011348309600278696 0.013133021332013151 5.387158688033522e-07 6.268640231373991 -0.038520740918736696 ELEEDFIK ddPTM_PC-9_AZD4547_30min_R2 1 ELEEDFIK 8 0 Q14019;H3BT58 Q14019 COTL1 Coactosin-like protein 0 139.19 0.012853999999999999 3346200.0 18785.0 17956.0 20671.0 25781.0 21779.0 23184.0 21943.0 22689.0 22397.0 23936.0 False True 24758.239247727022 23759.92585128202 20396.889033808537 19837.58876247941 18755.36178290466 21734.30081500426 23895.88449077639 19182.93639135185 23580.859695618285 23098.00792555139 1.0718776843235498 1.0286569269464318 0.8830583615500959 0.8588441404306018 0.8119904471137174 0.9409599687149395 1.0345430899407726 0.8305017667835924 1.0209044767680056 1.0 14.495480812149403 -5.134197759762065 4.374868778322103 0.9152270060511865 1.062223046432175 0.3208471791870253 0.0745714597816879 0.24540670037762938 7.427432253746095 0.019368192614601463 0.0577983974682887 7.341794770313061e-06 5.134197759762065 0.14699604038098846 ELEEDFIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ELEEDFIK 8 0 Q14019;H3BT58 Q14019 COTL1 Coactosin-like protein 0 ;; 155.01 0.00021669999999999998 3742900.0 30860.6 36110.0 36674.4 39095.8 37243.3 32061.2 37125.6 28617.5 32258.4 29103.8 False True 36084.69005536634 39694.76215732379 37548.856784436546 36905.38907629377 29945.742718266054 30379.85423148311 33608.794401932275 27866.32094774761 32730.118073102945 34380.08855444595 1.049581067780582 1.1545858031884144 1.092168704713264 1.0734524146977875 0.8710199414071474 0.883646770815384 0.9775656728954546 0.8105366251054639 0.9520079630181861 1.0 15.069285640389143 -6.1862062508600975 5.039081114454062 0.9079388503442445 1.1002351557710757 0.6958479394799503 0.05712429512244088 0.11322242856676408 5.282377915132073 0.016283485282253502 0.021122453187837575 6.513190025910356e-07 6.1862062508600975 0.19229630542683118 ELEEDFIK ddPTM_PC-9_Lapatinib_30min_R1 4 ELEEDFIK 8 0 Q14019;H3BT58 Q14019 COTL1 Coactosin-like protein 0 ;;; 127.02 0.015219 23581200.0 100080.0 115706.0 123151.0 112624.0 113410.0 106389.0 115952.0 107696.0 107010.0 107854.0 False True 98652.84084757589 115438.08986595548 113026.00015660754 120906.74466265057 106739.44677263888 101838.99047487196 121955.42720250665 112699.94932357752 94957.40693474395 126496.42019357844 0.779886424426926 0.9125798950618499 0.893511452605876 0.9558115911709284 0.8438139720420127 0.8050740907847588 0.9641018063268298 0.8909339027231911 0.7506726814041844 1.0 16.948737032146525 -10.590669269346794 4.3612468312787644 1.0000091255541244 0.872205416491937 0.2534591000714742 0.0681728918533884 47860418.01144992 0.40715859874264404 5280.954788139842 0.01633235207378267 2.5664377258860258e-11 10.590669269346794 -0.1278037090621874 ELEEEEENS(ph)DEDELDSHTMVK ddPTM_PC-9_AZD4547_30min_R2 4 ELEEEEENSDEDELDSHTMVK 21 0 A0A087WZ06;Q13188;Q13188-2;E5RFQ9 A0A087WZ06 STK3 Serine/threonine-protein kinase 3;Serine/threonine-protein kinase 3 36kDa subunit;Serine/threonine-protein kinase 3 20kDa subunit 1 ELEEEEENS(0.549)DEDELDS(0.437)HT(0.014)MVK;ELEEEEENS(0.999)DEDELDS(0.001)HTMVK;ELEEEEENS(0.999)DEDELDS(0.001)HTMVK;ELEEEEENS(0.88)DEDELDS(0.116)HT(0.004)MVK 106.12 5.3627e-05 66024700.0 120553.0 122405.0 154098.0 183370.0 179356.0 174703.0 142260.0 178710.0 155901.0 154518.0 True False 158886.3463418279 161970.02248976246 152054.55983415563 141096.8795382587 154455.5153099151 163778.7937924299 154920.86440586255 151094.4758472603 164141.6085818003 149108.37185161898 1.0655762944010898 1.0862570657732242 1.019758702653319 0.9462706740481837 1.0358607862985532 1.098387647578969 1.0389816646916896 1.0133198691057919 1.1008208764102207 1.0 17.186001736013502 -6.534864439452838 24.929850888456684 1.0522822261135563 1.0276084583323628 0.04460049382687925 0.04524243734969193 752.0767671621624 1564287.462934896 0.015797055983305233 0.015808303934500695 2.918337800918752e-07 6.534864439452838 -0.024673767781193456 ELEEEEENS(ph)DEDELDSHTMVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ELEEEEENSDEDELDSHTMVK 21 0 A0A087WZ06;Q13188;Q13188-2;E5RFQ9 A0A087WZ06 STK3 Serine/threonine-protein kinase 3;Serine/threonine-protein kinase 3 36kDa subunit;Serine/threonine-protein kinase 3 20kDa subunit 1 ELEEEEENS(0.997)DEDELDS(0.003)HTMVK;ELEEEEENS(0.999)DEDELDSHTMVK;ELEEEEENS(0.996)DEDELDS(0.004)HTMVK;ELEEEEENS(0.995)DEDELDS(0.004)HT(0.001)MVK 105.5 5.7786000000000005e-05 34022600.0 110922.5 111833.1 127668.6 128426.4 145504.2 124498.6 117414.5 121309.9 118096.2 100904.3 True False 129699.48843076229 122935.15108878985 130712.70360986197 121231.08517200626 116993.69652063935 117969.67424874054 106292.14855263448 118125.64366346337 119823.1335089395 119197.45083200044 1.08810622647932 1.0313572163724996 1.0966065356052908 1.0170610556334134 0.9815117328770134 0.989699640598939 0.8917317258944154 0.9910081368262842 1.005249128002082 1.0 16.862993856953693 -6.057853204256597 2.664016957616717 0.9719058738972747 1.068020534567835 0.6001079439609062 0.03451821230892361 0.19302763870086218 2.710836766939354 0.010901809282583027 0.01573460876166607 8.752795782117922e-07 6.057853204256597 0.0961146606705604 ELEEEEENS(ph)DEDELDSHTMVK ddPTM_PC-9_Lapatinib_30min_R1 8 ELEEEEENSDEDELDSHTMVK 21 0 A0A087WZ06;Q13188;Q13188-2;E5RFQ9 A0A087WZ06 STK3 Serine/threonine-protein kinase 3;Serine/threonine-protein kinase 3 36kDa subunit;Serine/threonine-protein kinase 3 20kDa subunit 1 ELEEEEENS(1)DEDELDSHTMVK;ELEEEEENS(0.829)DEDELDS(0.163)HT(0.008)MVK;ELEEEEENS(1)DEDELDSHTMVK;ELEEEEENS(1)DEDELDSHTMVK;ELEEEEENS(0.669)DEDELDS(0.319)HT(0.013)MVK;ELEEEEENS(0.537)DEDELDS(0.39)HT(0.073)MVK;ELEEEEENS(0.992)DEDELDS(0.006)HT(0.002)MVK;ELEEEEENS(0.526)DEDELDS(0.393)HT(0.081)MVK 137.04 4.8194e-05 59746500.0 176847.4 146151.4 160444.8 145043.4 151376.3 156070.6 132499.09999999998 148567.2 167204.5 136275.90000000002 True False 174325.5236461585 145812.99541281516 147253.64787883815 155710.37548659815 142472.64365125643 149395.82425633818 139359.25507492461 155470.17448322842 148372.16846855788 159831.0077387775 1.0906865076585788 0.9122947885752375 0.9213083866648994 0.9742188182976736 0.8913955162199126 0.9347111450395518 0.8719162635994185 0.9727159747207733 0.9283065318029681 1.0 17.286187797416986 -4.757389882195916 24.997742698037882 0.9308396315173897 1.0906867398514335 0.6124787103896772 0.037286064689360875 74.63366423225337 460654.66011781583 0.008707828175462102 0.06478369839087221 1.7482764915437562e-05 4.757389882195916 0.1598471083340438 ELEEEEENSDEDELDS(ph)HTMVK ddPTM_PC-9_AZD4547_30min_R2 1 ELEEEEENSDEDELDSHTMVK 21 0 A0A087WZ06;Q13188;Q13188-2;E5RFQ9 A0A087WZ06 STK3 Serine/threonine-protein kinase 3;Serine/threonine-protein kinase 3 36kDa subunit;Serine/threonine-protein kinase 3 20kDa subunit 1 ELEEEEENS(0.467)DEDELDS(0.516)HT(0.017)MVK 96.48700000000001 0.00032617 0.0 16781.0 14518.0 18533.0 23323.0 26683.0 20669.0 17035.0 22227.0 16903.0 26188.0 True False 22117.008933516496 19210.659585036337 18287.240310752928 17946.242686757963 22978.526032106376 19376.56416258294 18551.081998832236 18792.327875648018 17796.458071841564 25271.166091006842 0.8751875102980387 0.7601809713036062 0.7236405413543913 0.7101469960717178 0.9092784222681224 0.7667459464594476 0.7340809653193622 0.7436272551877048 0.7042199005678145 1.0 14.625204615850285 -10.664514829014395 4.6936664346265955 1.0000216608416945 0.7685007830709211 0.5282484765627986 0.06528840174884853 1.508735534017437e-05 2.7591539143493233e-06 0.06444788355421469 0.015629446136585543 2.165135949332647e-11 10.664514829014395 -0.23152087777077346 ELEEEEENSDEDELDS(ph)HTMVK ddPTM_PC-9_Lapatinib_30min_R1 2 ELEEEEENSDEDELDSHTMVK 21 0 A0A087WZ06;Q13188;Q13188-2;E5RFQ9 A0A087WZ06 STK3 Serine/threonine-protein kinase 3;Serine/threonine-protein kinase 3 36kDa subunit;Serine/threonine-protein kinase 3 20kDa subunit 1 ELEEEEENS(0.241)DEDELDS(0.379)HT(0.379)MVK;ELEEEEENS(0.007)DEDELDS(0.928)HT(0.066)MVK 91.475 0.00033169 0.0 12823.7 17304.6 19749.0 15357.5 17180.7 15194.3 15635.5 16589.3 16366.8 14572.2 True False 12640.831686421434 17264.532261891447 18125.31345334457 16486.94178111817 16170.165004555825 14544.475208643253 16445.029684910933 17360.099440217127 14523.39863395538 17090.985353764034 0.7396198302655195 1.0101542950587803 1.060518927269032 0.9646571827110698 0.9461224540219144 0.85100273083085 0.9622048901521738 1.0157459667118505 0.8497695324954929 1.0 14.060947955265027 -1.5234227720065248 0.00575999902911657 1.8256873885620668 1.4989095581398582e-05 0.031925848674326796 0.09131630738045676 253995.59351357503 113.56760301118385 16524.495785006744 19592.411825428906 0.0299624434929279 1.5234227720065248 -1.8256723994664854 ELEEIVQPIISK ddPTM_PC-9_Lapatinib_30min_R1 2 ELEEIVQPIISK 12 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 ; 123.84 0.0015669 7158300.0 52017.0 52902.0 55688.0 48915.0 48789.0 46755.0 53370.0 51894.0 46975.0 51582.0 False True 51275.228041250484 52779.50866928918 51109.54760189645 52512.372275656555 45919.32694286458 44755.3976412283 56133.23745858439 54305.18468836105 41684.18083132035 60497.87997130534 0.8475541302533373 0.8724191441803076 0.8448155146285811 0.8680035118679138 0.7590237371068955 0.739784562078145 0.9278546204463507 0.897637813326987 0.6890188689436971 1.0 15.884596966424711 -9.871965410430509 8.946993429769474 0.9999941653223159 0.8308198415323469 0.34371326331322893 0.0714276213069006 0.0 0.0 0.06987327640514253 0.016946758766257706 1.3428719104856237e-10 9.871965410430509 -0.169174323789969 ELEEVS(ph)PETPVVPATTQR ddPTM_PC-9_AZD4547_30min_R2 3 ELEEVSPETPVVPATTQR 18 0 Q15149 Q15149 PLEC Plectin 1 ELEEVS(0.987)PET(0.013)PVVPATTQR;ELEEVS(0.993)PET(0.007)PVVPATTQR;ELEEVS(0.998)PET(0.002)PVVPATTQR 185.63 1.3174000000000003e-10 35627200.0 30187.9 34168.0 47788.0 60048.0 48674.0 49949.0 41109.2 54951.0 45364.0 44465.0 True False 39787.02425267284 45212.13780834288 47154.29989587547 46204.861332351895 41916.455274397405 46825.681133913386 44767.83916092715 46459.585598359365 47761.848427558485 42908.29388409265 0.9272571955470605 1.0536922752154527 1.0989553680053668 1.0768282108154708 0.976884687786131 1.0912967376517626 1.043337665250864 1.0827646916901368 1.1131146010274062 1.0 15.388968917459492 -4.764102961145584 5.403233861360972 1.0623705261573244 0.9205849889425163 0.48231951086430846 0.041156282707746024 0.12849243313184994 11.488893611176964 0.010095167089618157 0.0682784901478087 1.7214604082813266e-05 4.764102961145584 -0.14178553721480813 ELEEVS(ph)PETPVVPATTQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ELEEVSPETPVVPATTQR 18 0 Q15149 Q15149 PLEC Plectin 1 ELEEVS(0.991)PET(0.009)PVVPATTQR;ELEEVS(0.975)PET(0.025)PVVPATTQR;ELEEVS(0.78)PET(0.22)PVVPATTQR;ELEEVS(0.998)PET(0.002)PVVPATTQR;ELEEVS(1)PETPVVPATTQR 229.02 3.490099999999999e-35 36500000.0 65349.3 88488.8 75687.1 76797.3 86503.6 64794.1 77352.0 62128.3 57887.0 53832.7 True False 76411.64578249137 97273.3832618939 77491.767508925 72494.5962612061 69553.84055128845 61396.18333250591 70024.65858001678 60497.497955375184 58733.487863555274 63592.142370581285 1.2015894249513535 1.5296446956455125 1.2185745694388477 1.1399929859061209 1.0937489752423428 0.965468075831154 1.1011526891475083 0.951336056628315 0.9235966217537955 1.0 15.956560892490979 -5.911600459174599 1.2314082047628732 0.9925736291350657 1.3719570924114053 0.7044327286489236 0.09264079005866681 0.24740848406279384 0.7581566023984627 0.0329164883366067 0.07007404409773085 1.2257433360846822e-06 5.911600459174599 0.37938346327633954 ELEEVS(ph)PETPVVPATTQR ddPTM_PC-9_Lapatinib_30min_R1 4 ELEEVSPETPVVPATTQR 18 0 Q15149 Q15149 PLEC Plectin 1 ELEEVS(0.98)PET(0.02)PVVPATTQR;ELEEVS(1)PETPVVPATTQR;ELEEVS(0.888)PET(0.112)PVVPATTQR;ELEEVS(0.998)PET(0.002)PVVPATTQR 260.07 1.2315999999999997e-65 36988200.0 47206.9 70629.5 82146.9 75198.3 86369.8 80077.2 77717.4 83726.0 80879.8 60537.6 True False 46533.72094931481 70465.96173221343 75393.09897820416 80728.6338361751 81289.69817356013 76652.48482507042 81741.22669784131 87616.21561679026 71770.2652219484 71001.44349871852 0.6553911956755454 0.9924581566216361 1.0618530449956964 1.136999895468775 1.1449020494213937 1.0795905132049026 1.1512614768080964 1.2340061173315668 1.0108282548261678 1.0 16.115560735255123 -4.413786162308795 1.3524719122175295 1.1191842571134933 1.1827412069585824e-11 0.8020806111596746 0.06668149480237895 1.2041080654885383 1.0203281632149666 0.018419743929105198 2.3517198678779097 3.856682060339898e-05 4.413786162308795 -1.119184257101666 ELEEVSPET(ph)PVVPATTQR ddPTM_PC-9_AZD4547_30min_R2 1 ELEEVSPETPVVPATTQR 18 0 Q15149 Q15149 PLEC Plectin 1 ELEEVS(0.397)PET(0.603)PVVPATTQR 130.64 0.00010079 9214200.0 15628.0 17784.0 21390.0 28162.0 18377.0 21853.0 20875.0 25893.0 25359.0 23983.0 True False 20597.37891740634 23532.330214925354 21106.354624022282 21669.685998562716 15825.67076011013 20486.528455412703 22732.83455976654 21891.831811947355 26699.424968575433 23143.36246985706 0.8899907670820641 1.0168068812634683 0.9119830643240425 0.9363240119834045 0.6838103486786842 0.8852010368888819 0.9822615270090848 0.945922695565964 1.1536536665037307 1.0 14.498310866560612 -7.833158021213186 1.8401737398187166 1.06645331671329 0.8915780247537486 0.3626804895758423 0.09063697671221507 0.4190621105505123 2.6958649721473966 0.07389921615703292 0.027967562452110437 1.4683918953348259e-08 7.833158021213186 -0.17487529195954132 ELEEVSPET(ph)PVVPATTQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELEEVSPETPVVPATTQR 18 0 Q15149 Q15149 PLEC Plectin 1 ELEEVS(0.234)PET(0.754)PVVPAT(0.006)T(0.006)QR 123.58 0.00014576 0.0 3357.3 3580.7 4637.8 3983.7 4784.2 3917.7 3671.8 5943.4 3295.1 2955.3 True False 3925.62458030244 3936.168231978102 4748.382740954444 3760.5062043296602 3846.7703536670615 3712.2489152833123 3323.980522470072 5787.39204755283 3343.2846037832514 3491.072495858073 1.1244752393311608 1.1274954148469003 1.3601501391300486 1.0771779184738364 1.1018878462796176 1.0633548629218244 0.9521373521786659 1.6577690822574405 0.9576669083067847 1.0 11.769454600970962 -12.047425272099526 1.185484089441045 0.3096184808248582 1.1648988512831897 0.052980474117540255 0.1985584046142008 113225.73842693883 8208.211888077936 206538.7771227357 0.05611165703278381 8.965504397365539e-13 12.047425272099526 0.8552803704583315 ELEEWYAR ddPTM_PC-9_AZD4547_30min_R2 1 ELEEWYAR 8 0 P09496-2;F8WF69;P09496-5;P09496-4;P09496-3;P09496;C9J8P9 P09496-2 CLTA Clathrin light chain A 0 98.62899999999999 0.021449 0.0 13804.0 18901.0 19814.0 22118.0 21539.0 22133.0 19149.0 24532.0 22226.0 19973.0 False True 18193.384858963214 25010.37862079984 19551.253413762384 17019.036819693563 18548.68164020309 20749.02001114947 20853.22390347159 20741.14308927868 23400.820984721708 19273.751349308048 0.9439462266185342 1.2976393732348188 1.0143979269746208 0.8830163112125325 0.9623804574436937 1.0765428916822872 1.0819494101349527 1.076134205187996 1.2141290276405805 1.0 14.234349777665768 -6.9835672775469355 24.053267030740724 1.0965189063902094 1.0269058702856704 0.08523074969291378 0.11356890464914475 462.38165011699596 676803.6385555182 0.04220100805035198 0.03720582241060049 1.0385627038474469e-07 6.9835672775469355 -0.06961303610453906 ELEEWYAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELEEWYAR 8 0 P09496-2;F8WF69;P09496-5;P09496-4;P09496-3;P09496;C9J8P9 P09496-2 CLTA Clathrin light chain A 0 94.11399999999999 0.031481 3182800.0 11347.0 13712.0 15108.0 13779.0 17753.0 14971.0 15109.0 10147.0 12421.0 10576.0 False True 13267.822986534362 15073.236740548993 15468.232017409064 13007.007302120734 14274.427090976822 14185.894405060742 13677.766140312742 9880.652001635191 12602.633626776651 12493.345080430072 1.061991236223632 1.2065012727584172 1.2381177273041901 1.0411148670259078 1.1425624601802353 1.1354760725597763 1.0948041579142789 0.7908732159421837 1.0087477409487209 1.0 13.60887218834649 -7.601630099631984 7.395883153608324 0.9257388070073745 1.1390606108595165 0.5807341535223096 0.07783167656439378 0.15223997009404297 12.112537352408976 0.03592825441305969 0.020612955682200527 2.502475880715124e-08 7.601630099631984 0.21332180385214194 ELEEWYAR ddPTM_PC-9_Lapatinib_30min_R1 3 ELEEWYAR 8 0 P09496-2;F8WF69;P09496-5;P09496-4;P09496-3;P09496;C9J8P9 P09496-2 CLTA Clathrin light chain A 0 ;; 107.29 0.017565 9661500.0 67852.0 50518.0 65739.0 53624.0 63795.0 65330.0 58066.0 58689.0 58883.0 51994.0 False True 66884.41803746714 50401.02867481669 60334.193179878435 57567.68784442007 60042.70352579571 62535.98819166823 61072.37336087998 61415.90519472811 52250.97647452125 60981.093622349894 1.096805814137673 0.8265025384251956 0.9893917867974351 0.944025179360201 0.9846117863617608 1.0254979777658244 1.001496853091802 1.0071302685234045 0.8568389540224807 1.0 15.896074403124285 ELEKPIQSKPQSPVIQAAAVS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 ELEKPIQSKPQSPVIQAAAVSPK 23 2 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 1 ELEKPIQSKPQSPVIQAAAVS(1)PK 78.257 8.6918e-05 77655000.0 307080.0 349760.0 316700.0 375850.0 347380.0 345750.0 372180.0 291200.0 314550.0 347800.0 True False 404725.0523392082 462813.0800704168 312500.35107189615 289203.58932461427 299152.2832152725 324130.19784280984 405303.29899180477 246201.7311103029 331176.47083344765 335623.6278620806 1.2058896297537305 1.3789645354188316 0.9311035491229283 0.861690194956888 0.8913326070660452 0.9657550033277341 1.207612531851774 0.7335649539295123 0.9867495710687555 1.0 18.356484759343076 -5.2691087010951 24.671646379303848 0.9426207196263195 1.292427087935815 0.5695134299916137 0.11999593804363076 297.31591183104285 956446.2002887221 0.031239994438551133 0.06706656730988307 5.381350739361285e-06 5.2691087010951 0.3498063683094955 ELEKPIQSKPQSPVIQAAAVS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ELEKPIQSKPQSPVIQAAAVSPK 23 2 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 1 ELEKPIQSKPQSPVIQAAAVS(1)PK;ELEKPIQSKPQSPVIQAAAVS(1)PK;ELEKPIQSKPQSPVIQAAAVS(1)PK 125.54 6.5475e-07 113204400.0 302128.0 312457.0 198705.0 348460.0 292529.0 257306.0 325440.0 272264.0 276129.0 276870.0 True False 353272.30309999525 343475.6660036252 203442.88079290916 328936.9159225623 235210.04238699732 243812.4203986746 294611.96721843816 265117.3584875536 280166.864240255 327064.3392982857 1.0801309120338174 1.0501776706703942 0.6220270948199197 1.0057254075094038 0.7191552674059142 0.7454570587602809 0.900776794714233 0.8105969579452198 0.8566108577943747 1.0 18.319214941524436 -5.104536363092864 9.564985853115413 0.8273276097944839 1.0726450815804474 0.40243775803659165 0.11348664731446172 0.3053376498866664 25.46202745296512 0.026753092104502767 0.07115032305427928 7.860743710807813e-06 5.104536363092864 0.24531747178596341 ELEKPIQSKPQSPVIQAAAVS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 ELEKPIQSKPQSPVIQAAAVSPK 23 2 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 1 ELEKPIQSKPQSPVIQAAAVS(1)PK;ELEKPIQSKPQSPVIQAAAVS(1)PK 112.06 1.6204000000000001e-07 90858900.0 312423.0 278768.0 197910.0 234433.0 201202.0 190531.0 207688.0 210020.0 217368.0 147640.0 True False 307967.79072863894 278122.52982345474 181638.60375469286 251673.98486556252 189367.69393835176 182382.4332794542 218441.0684148113 219778.295915705 192885.7268534847 173159.37728206613 1.7785221658944759 1.606164991979672 1.048967757944836 1.4534239428200348 1.0936034589098993 1.0532633931939146 1.2615029682105177 1.2692254925224147 1.1139201923744826 1.0 17.401740991870966 -5.122826525819996 4.114293005579274 1.1796597824065478 1.7455354409006045 0.7278421063791621 0.13088844926847507 0.11103973813275357 3.092681281258265 0.03303935976525702 0.10197312769598296 7.536565434801477e-06 5.122826525819996 0.5658756584940567 ELENHS(ph)RR ddPTM_PC-9_AZD4547_30min_R2 1 ELENHSRR 8 1 B1AKB5;B0QYS6;B0QYS7;P19484-2;P19484 B1AKB5 TFEB Transcription factor EB 1 ELENHS(1)RR 76.847 0.035812000000000004 7673500.0 1857.2 4984.9 3693.5 3536.9 11095.0 8140.4 8538.0 7786.4 7324.4 1673.4 True False 2447.750967840226 6596.1714399674665 3644.5217767099707 2721.522349560275 9554.650763640524 7631.379501141332 9297.865459702358 6583.190793671917 7711.552830941042 1614.814775343319 1.5158091226405952 4.084785165880763 2.256928678358869 1.6853464503268887 5.916871030368885 4.725854393745473 5.757852604318398 4.076746692060885 4.775503016624009 1.0 10.657152977123872 -4.759391750605784 24.322816250972437 3.9456021640158885 1.5158046842987754 0.15364586378752054 1.5855976619477732 72.69581742643958 863204.8453031651 0.40478627235646053 2.569691437263825 1.740236403897308e-05 4.759391750605784 -2.429797479717113 ELEQHIQT(ph)SDPENFQSEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELEQHIQTSDPENFQSEER 19 0 Q96K76-2;Q96K76-4;Q96K76 Q96K76-2 USP47 Ubiquitin carboxyl-terminal hydrolase 47 1 ELEQHIQT(0.497)S(0.497)DPENFQS(0.007)EER 79.172 0.0060215 6026000.0 16864.0 18955.0 20860.0 25929.0 26417.0 18809.0 21140.0 18159.0 18299.0 18075.0 True False 19718.742120817424 20836.727130769126 21357.381511990534 24476.2821929522 21240.778486021227 17822.622928647874 19137.466159653944 17682.345491050903 18566.588256693165 21351.854418378723 0.9235142641214531 0.9758743536970634 1.0002588577789784 1.1463305113154063 0.9947978320673689 0.8347107740350157 0.896290588380055 0.8281409728904262 0.8695538988272548 1.0 14.38207375356464 -6.683731475029195 6.384226016734176 0.8759515217123299 1.0151196198193881 0.438315206931553 0.06883329165040855 0.18859230068252456 12.266089601482136 0.02339340067720605 0.023267128494378137 2.071421716274447e-07 6.683731475029195 0.1391680981070582 ELEQHIQTS(ph)DPENFQSEER ddPTM_PC-9_AZD4547_30min_R2 2 ELEQHIQTSDPENFQSEER 19 0 Q96K76-2;Q96K76-4;Q96K76 Q96K76-2 USP47 Ubiquitin carboxyl-terminal hydrolase 47 1 ELEQHIQT(0.237)S(0.746)DPENFQS(0.018)EER;ELEQHIQT(0.218)S(0.781)DPENFQSEER 87.802 0.00065406 18462000.0 54529.0 51838.0 66383.0 81939.0 70703.0 79520.0 56663.0 77902.0 68762.0 74608.0 True False 71868.08772634054 68593.61975265984 65502.718046118374 63049.229494930405 60887.10887261612 74547.60182924173 61705.897229224 65864.03590987225 72396.61893959471 71995.99662890777 0.998223388680533 0.9527421379582401 0.909810560491884 0.8757324357895607 0.8457013129000672 1.0354409317157705 0.8570740057572577 0.9148291432002565 1.0055645081594173 1.0 16.13562906660166 -8.26313751845014 24.51068803876114 1.002782269201586 0.9215054366065625 0.23735928284446106 0.05659712029768534 168.33320379002544 2429548.480242815 0.04657985030408095 0.014381687845546413 5.455850753500395e-09 8.26313751845014 -0.0812768325950235 ELEQHIQTS(ph)DPENFQSEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELEQHIQTSDPENFQSEER 19 0 Q96K76-2;Q96K76-4;Q96K76 Q96K76-2 USP47 Ubiquitin carboxyl-terminal hydrolase 47 1 ELEQHIQT(0.015)S(0.985)DPENFQSEER 113.59 4.8738e-05 6578800.0 54739.0 60152.0 68876.0 64922.0 74005.0 60760.0 64678.0 55895.0 55869.0 49496.0 True False 64005.23155546874 66123.49302928124 70518.26505368443 61284.630819963895 59504.2514993376 57573.638638133096 58551.23161183053 54427.815475647854 56685.97843123616 58469.232989879594 1.0946822505187876 1.1309109021615953 1.2060747413240465 1.048151783187777 1.0177019341033113 0.9846826389547214 1.0014024234243868 0.9308795873048092 0.9695009756849026 1.0 15.835390045452435 -6.105636581591775 2.2943704537972325 0.9784062192993302 1.141775722298672 0.7999340711599212 0.035333130278943754 0.12957944262078114 1.3419821910322896 0.01162887586253813 0.016604460240802008 7.840854924785783e-07 6.105636581591775 0.16336950299934172 ELEQHIQTS(ph)DPENFQSEER ddPTM_PC-9_Lapatinib_30min_R1 2 ELEQHIQTSDPENFQSEER 19 0 Q96K76-2;Q96K76-4;Q96K76 Q96K76-2 USP47 Ubiquitin carboxyl-terminal hydrolase 47 1 ELEQHIQT(0.226)S(0.774)DPENFQSEER;ELEQHIQT(0.189)S(0.811)DPENFQSEER 159.98 4.3508e-06 20988200.0 74094.0 70322.0 88860.0 76514.0 75664.0 89891.0 83361.0 78391.0 79883.0 68496.0 True False 73037.40597282439 70159.17372957067 81554.27380951935 82141.09480322152 71213.59228114752 86046.5714761556 87677.02469149449 82033.33204041506 70885.73533471773 80335.4423348172 0.9091554592856227 0.8733277827383523 1.015171777726976 1.0224764116052145 0.8864529802966393 1.0710910275135588 1.091386592807686 1.021135001641262 0.8823718806362507 1.0 16.293748994934916 -5.263002737982974 24.965753593990964 1.0022428244418813 0.8912416150533475 0.3044123503038716 0.06484082926726532 155.39616879163356 2481619.11694102 0.01745799735697775 0.03981602679924136 5.457544204050928e-06 5.263002737982974 -0.11100120938853375 ELESERR ddPTM_PC-9_Lapatinib_30min_R1 1 ELESERR 7 1 B3KT41;Q496J9 B3KT41 SV2C Synaptic vesicle glycoprotein 2C 0 82.305 0.014348 1335000.0 5232.4 7502.1 5553.7 5262.7 6554.4 5915.2 5452.8 6512.8 7226.8 6421.1 False True 5157.785016495359 7484.729348377647 5097.096223901961 5649.736513852551 6168.883078446202 5662.220685004678 5735.11930324469 6815.408464145327 6412.841682422266 7530.978579422059 0.6848758049304101 0.9938588019396596 0.6768172515892512 0.7501995197928345 0.8191343280808552 0.7518572288170294 0.7615370622505228 0.9049831163732183 0.8515283392180886 1.0 12.878621626312393 -8.469365713218517 0.9491674954023438 0.9948257368547446 0.7810775933062919 0.3684806304254551 0.08796751808226744 0.6212544920238984 1.238207560217452 0.08083446542565535 0.027701521442461612 3.3933939935104116e-09 8.469365713218517 -0.21374814354845273 ELESPLT(ph)PGK ddPTM_PC-9_AZD4547_30min_R2 3 ELESPLTPGK 10 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 ELES(0.434)PLT(0.566)PGK;ELES(0.012)PLT(0.988)PGK;ELES(0.002)PLT(0.998)PGK 132.56 0.00034786 42366400.0 200383.0 219561.0 220760.0 179210.0 209488.0 235813.0 247737.0 264377.0 235479.0 214351.0 True False 264100.62577467586 290529.79950063134 217832.57815797863 137895.90326689938 180404.20722609505 221067.5758319788 269785.113069839 223523.60942908173 247925.9392000934 206846.63673336667 1.2767943919490061 1.4045662239852394 1.0531115303497696 0.6666577008194363 0.8721640828931778 1.068751125583654 1.3042760439832652 1.0806248192336447 1.1985978748094392 1.0 17.658201974395453 -5.2957977671934415 8.01861682731149 1.0254888381653382 1.3405839008623859 0.3591611874216831 0.16564425432820112 0.2990048645528813 64.31973934594971 0.04901319719342564 0.10434201324805947 5.060602582772688e-06 5.2957977671934415 0.3150950626970477 ELESPLT(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 ELESPLTPGK 10 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 ELES(0.028)PLT(0.972)PGK;ELESPLT(1)PGK;ELES(0.015)PLT(0.985)PGK;ELES(0.024)PLT(0.976)PGK;ELES(0.145)PLT(0.855)PGK;ELES(0.039)PLT(0.961)PGK 168.85 0.00046576 43703500.0 229007.0 325737.0 274157.0 281628.0 304092.0 214393.0 302141.0 221803.0 204183.0 203455.0 True False 267773.3620055765 358074.01663916244 280693.9426262123 265849.29621029465 244507.3555426875 203149.85366269384 273520.01716859 215980.90626970463 207168.79009871435 240339.7809511063 1.1141449865099575 1.489865785939147 1.1679046286695063 1.1061393796658985 1.0173403444701858 0.8452610419247315 1.1380555315735839 0.8986481780710405 0.8619829363198924 1.0 17.87471593701565 -5.893256471532595 1.6466347804933739 0.9553991699985741 1.3024265398853665 0.567619525368253 0.11839745893261473 0.2546143293626872 1.405224295513432 0.03776347077761705 0.07074543421332614 1.2786259917372213e-06 5.893256471532595 0.3470273698867924 ELESPLT(ph)PGK ddPTM_PC-9_Lapatinib_30min_R1 4 ELESPLTPGK 10 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 ELES(0.002)PLT(0.998)PGK;ELES(0.003)PLT(0.997)PGK;ELES(0.007)PLT(0.993)PGK;ELES(0.011)PLT(0.989)PGK 145.23 0.00030243 61311500.0 228437.0 329786.0 284596.0 296195.0 320781.0 286871.0 318484.0 331502.0 281870.0 264949.0 True False 225179.4464897845 329022.40077899216 261197.61545232873 317978.1683775555 301913.2922597109 274602.19605896267 334973.5431658194 346904.79312754987 250122.8323773131 310745.0816276492 0.7246436381561339 1.0588177262713487 0.8405526938164357 1.0232765928651877 0.97157866724172 0.8836895973401284 1.077968930067257 1.1163645497154775 0.8049132461476034 1.0 18.24537203138616 -4.7496047343330785 24.94381746233324 0.9764036547880117 0.7246430582732377 0.3706790299545607 0.09794597522548848 568.6508753466853 1198465.7782115992 0.023533117323258787 0.3776544691822366 1.7798986172502775e-05 4.7496047343330785 -0.251760596514774 ELESQISELQEDLESER ddPTM_PC-9_AZD4547_30min_R2 1 ELESQISELQEDLESER 17 0 P35579 P35579 MYH9 Myosin-9 0 196.97 1.4696e-11 1145000.0 2941.1 2509.3 4401.8 4204.3 4017.8 2942.1 3967.0 3794.6 3560.4 4008.1 False True 3876.308621319668 3320.3821529640218 4343.429255914972 3235.0635907874866 3459.997822276242 2758.130021904071 4320.055314902702 3208.2317612333627 3748.5954752993384 3867.7776389706924 1.0022056548088545 0.8584728655310325 1.1229780151143491 0.8364140580864452 0.8945699947727682 0.7131045989081407 1.1169347667184848 0.8294767850426762 0.9691858801626788 1.0 11.917289140393189 -5.830287401810979 24.999949493799285 0.9013812550566102 0.9809823551589401 0.09383017208886735 0.11886727269230649 123.05981662921243 44683.179102600865 0.032243574376004405 0.04782496804190454 1.4781298866674017e-06 5.830287401810979 0.0796011001023299 ELESQISELQEDLESER ddPTM_PC-9_Lapatinib_30min_R1 2 ELESQISELQEDLESER 17 0 P35579 P35579 MYH9 Myosin-9 0 ; 260.29 1.7923e-57 4405400.0 11248.9 10886.2 12894.400000000001 8681.0 11035.5 13801.6 9750.6 9605.6 12138.7 11167.400000000001 False True 11088.488623204392 10860.993672746134 11834.2722058234 9319.429698967071 10386.413586627772 13211.337741100988 10255.438357947782 10051.911242966826 10771.511779822207 13097.67021037486 0.8466000781132079 0.8292309623235878 0.9035402492001438 0.7115333909984245 0.7929970307544115 1.0086784541754679 0.7829971432495144 0.7674579586684476 0.8223990684457708 1.0 13.67702259017777 ELEVLLMCNK ddPTM_PC-9_Lapatinib_30min_R1 2 ELEVLLMCNK 10 0 D3YTB1;F8W727;P62910 D3YTB1 RPL32 60S ribosomal protein L32 0 ; 186.25 0.0005761 14330100.0 97305.0 84127.0 104880.0 89416.0 96011.0 86762.0 96605.0 74512.0 84036.0 94875.0 False True 95917.41285644827 83932.20910024754 96257.17124850785 95991.95092303179 90363.82174488869 83051.39151210035 101606.73420810481 77974.09953942947 74570.98074168897 111274.01733700868 0.8619928996177892 0.7542839838885953 0.8650462484604986 0.862662760097058 0.8120837542084007 0.7463682313236502 0.9131218287947206 0.7007395024057969 0.6701562730124184 1.0 16.763757234815543 -6.521908931856158 24.88612529199407 0.7924150481362315 0.832877154570804 0.011432788932062676 0.09595843279328643 142.7404594824643 3663010.199895932 0.030809892072901024 0.031177007049410673 3.006706719326972e-07 6.521908931856158 0.04046210643457249 ELEVQHPAAK ddPTM_PC-9_Lapatinib_30min_R1 1 ELEVQHPAAK 10 0 P50990-2;P50990;H7C4C8 P50990-2 CCT8 T-complex protein 1 subunit theta 0 66.92 0.037722000000000006 2543400.0 65872.0 53547.0 59603.0 55353.0 60154.0 62422.0 57084.0 55818.0 61159.0 55543.0 False True 64932.653200554705 53423.01521141786 54702.67141423349 59423.84427219499 56615.859987314325 59752.3565727891 60039.53020584288 58411.50805362733 54270.62938717872 65143.53354360461 0.9967628353640235 0.8200816305989684 0.8397252718509289 0.9121986640841171 0.8690940897367475 0.9172415637047557 0.9216498851057058 0.8966585764729647 0.8330931166153587 1.0 15.991334356691516 -6.766951366981923 24.948459056649824 0.90776486814502 0.882532946674417 0.03933066008332853 0.05859260321800837 527.870022202093 2389243.6537060966 0.01988904920979379 0.018027657640744963 1.7102068161701942e-07 6.766951366981923 -0.025231921470603047 ELFDDPS(ph)YVNVQNLDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELFDDPSYVNVQNLDK 16 0 P29353-2;P29353-7;P29353;P29353-6;Q5T188;H0Y539;X6R6D0;P29353-5;P29353-3 P29353-2 SHC1 SHC-transforming protein 1 1 ELFDDPS(0.895)Y(0.105)VNVQNLDK;ELFDDPS(0.594)Y(0.406)VNVQNLDK 215.51 5.332599999999999e-22 9043500.0 40052.0 32006.0 54753.0 55150.0 100836.0 105899.0 118666.0 115742.0 112759.0 91722.0 True False 46832.01253694143 35183.344159714936 56058.519171908825 52060.12429871243 81077.90965728251 100345.47001546495 107425.09741255862 112703.89513878574 114407.8870559303 108350.47252904756 0.4322271185701224 0.3247179577392491 0.5173814000384738 0.48047897792744454 0.7482930878362937 0.9261193576111395 0.9914594270344242 1.0401790828237605 1.0559057508979375 1.0 16.725345919643452 -6.474437601240241 1.183299579314557 1.0373663523076104 0.3928619831611706 0.9742147189381918 0.043628033895240635 0.06199453420515288 0.18171201399191514 0.01868865473658161 0.022222260919641957 3.3539949066912326e-07 6.474437601240241 -0.6445043691464398 down ELFDDPS(ph)YVNVQNLDK ddPTM_PC-9_Lapatinib_30min_R1 1 ELFDDPSYVNVQNLDK 16 0 P29353-2;P29353-7;P29353;P29353-6;Q5T188;H0Y539;X6R6D0;P29353-5;P29353-3 P29353-2 SHC1 SHC-transforming protein 1 1 ELFDDPS(0.88)Y(0.12)VNVQNLDK 159.14 6.3627e-15 0.0 4783.2 4428.9 7068.5 5230.1 8337.0 9737.2 7867.2 8341.4 9152.3 9031.3 True False 4714.990690868549 4418.645154160802 6487.355215199054 5614.739001102144 7846.6340511726485 9320.762654521843 8274.525121494762 8728.971895777828 8121.471596008374 10592.348171549189 0.44513177007652643 0.4171544479654837 0.612456757475547 0.5300750041603813 0.7407832450455635 0.879952443364466 0.7811794880119172 0.824082795845368 0.7667300455457522 1.0 13.37073482911763 -6.100558919714753 0.9409347583440519 0.8503896592913336 0.42707174528743697 0.8293774934905804 0.07526203901224718 0.23904066098613364 0.4384244516319885 0.03370805034523879 0.06555999733219917 7.933066234253257e-07 6.100558919714753 -0.4233179140038966 ELFDDPSY(ph)VNVQNLDK ddPTM_PC-9_AZD4547_30min_R2 4 ELFDDPSYVNVQNLDK 16 0 P29353-2;P29353-7;P29353;P29353-6;Q5T188;H0Y539;X6R6D0;P29353-5;P29353-3 P29353-2 SHC1 SHC-transforming protein 1 1 ELFDDPS(0.024)Y(0.976)VNVQNLDK;ELFDDPS(0.064)Y(0.936)VNVQNLDK;ELFDDPS(0.07)Y(0.93)VNVQNLDK;ELFDDPS(0.005)Y(0.995)VNVQNLDK 304.08 2.7796999999999994e-128 53036900.0 140952.0 163663.0 196385.0 242635.0 243855.0 208606.0 197200.0 238570.0 220945.0 230865.0 True False 185771.80401626966 216563.8641455986 193780.8065843206 186699.24942338106 209999.94249369655 195561.83384294272 214750.41797298036 201704.48829321715 232623.7016318426 222782.48661983648 0.833870771598294 0.9720865739107691 0.8698206466965004 0.8380337801955273 0.9426232092114472 0.8778151137914895 0.963946588581883 0.9053875434895045 1.0441740962735526 1.0 17.765276298408253 -7.931803825149375 1.085549162319535 1.0172754800609753 0.8913289677762047 0.483722237036625 0.04841118838142661 0.438100525604575 0.9385857364255565 0.041742031857118916 0.015352761833192487 1.1700277840865922e-08 7.931803825149375 -0.1259465122847706 ELFDDPSY(ph)VNVQNLDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ELFDDPSYVNVQNLDK 16 0 P29353-2;P29353-7;P29353;P29353-6;Q5T188;H0Y539;X6R6D0;P29353-5;P29353-3 P29353-2 SHC1 SHC-transforming protein 1 1 ELFDDPS(0.286)Y(0.714)VNVQNLDK;ELFDDPS(0.054)Y(0.946)VNVQNLDK;ELFDDPS(0.374)Y(0.626)VNVQNLDK;ELFDDPS(0.376)Y(0.624)VNVQNLDK 239.38 3.6366999999999995e-37 27838600.0 65315.6 55340.6 95011.0 102555.0 176175.0 176127.0 219602.0 209089.0 205367.0 161270.0 True False 76372.24103809676 60834.449034715995 97276.42257122399 96809.17583779585 141654.77343281926 166890.59006613688 198799.70877920155 203600.63529810746 208370.10385880707 190506.9743873826 0.40088947548344955 0.3193292488652589 0.5106186945860532 0.5081660456217271 0.7435673884819262 0.8760340171419475 1.0435298204618813 1.0687306118467863 1.0937662756382927 1.0 17.539484289635233 -6.497405547857915 0.9608169765657768 1.0774843937989895 0.3654590308092762 0.9742568592497701 0.04558140441888029 0.07323240220401271 0.14646679051462294 0.022908596646456118 0.02780066718664126 3.181225479042339e-07 6.497405547857915 -0.7120253629897133 down ELFDDPSY(ph)VNVQNLDK ddPTM_PC-9_Lapatinib_30min_R1 6 ELFDDPSYVNVQNLDK 16 0 P29353-2;P29353-7;P29353;P29353-6;Q5T188;H0Y539;X6R6D0;P29353-5;P29353-3 P29353-2 SHC1 SHC-transforming protein 1 1 ELFDDPS(0.001)Y(0.999)VNVQNLDK;ELFDDPS(0.166)Y(0.834)VNVQNLDK;ELFDDPS(0.226)Y(0.774)VNVQNLDK;ELFDDPS(0.019)Y(0.981)VNVQNLDK;ELFDDPS(0.025)Y(0.975)VNVQNLDK;ELFDDPS(0.03)Y(0.97)VNVQNLDK 281.32 1.7788999999999996e-127 26690600.0 97913.1 95376.3 124910.7 93949.9 165741.7 200932.0 198994.4 178595.0 232473.0 172995.3 True False 96516.84123893655 95155.46203725235 114641.02441524566 100859.28905367915 155993.09906671947 192338.60675536934 209297.35634492262 186893.1756931021 206289.44269078312 202897.30710325207 0.4756930617606485 0.46898336599819357 0.5650199406387695 0.49709525717043174 0.7688278434732325 0.947960372177293 1.0315432931715236 0.9211220117278064 1.0167184850107687 1.0 17.630390191899224 -6.4936480230760925 2.0179639716204516 0.9880409312338092 0.49595300145599946 0.9718732168085635 0.038624421872021975 0.04849319962407704 0.3954725297922882 0.014001401906150651 0.015457512846037993 3.208868920627979e-07 6.4936480230760925 -0.49208792977780974 ELFPPS(ph)PSEMGELEATR ddPTM_PC-9_AZD4547_30min_R2 1 ELFPPSPSEMGELEATR 17 0 Q8WYA1-6;Q8WYA1-8;Q8WYA1-7;Q8WYA1-4;Q8WYA1-3;H0Y5R1;Q8WYA1-5;Q8WYA1-2;Q8WYA1 Q8WYA1-6 ARNTL2 Aryl hydrocarbon receptor nuclear translocator-like protein 2 1 ELFPPS(0.988)PS(0.012)EMGELEATR 95.073 0.012294 0.0 5100.4 4604.8 6497.9 7609.2 6340.5 5221.9 4341.0 5788.0 4604.4 7002.6 True False 6722.221105089536 6093.211548228089 6411.733600347559 5855.016500968088 5460.2310199966405 4895.373767506502 4727.340590368698 4893.597595008355 4847.779183931099 6757.441105425557 0.9947879678436645 0.9017039813097065 0.9488404708698935 0.8664546844910107 0.8080323505317146 0.724441943500773 0.6995755518421183 0.724179096593129 0.717398658500895 1.0 12.722261317647622 -6.150624565789726 1.7235047233928855 0.7521550892770494 0.9470597699593521 0.43604044331805736 0.08510598794562645 0.2967093194450807 1.747628667151253 0.027846832811207037 0.04059635055891033 7.06928408039428e-07 6.150624565789726 0.1949046806823027 ELFQT(ph)PCTDNPTTDEK ddPTM_PC-9_AZD4547_30min_R2 1 ELFQTPCTDNPTTDEK 16 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ELFQT(0.769)PCT(0.228)DNPT(0.002)T(0.001)DEK 125.86 7.3935e-05 4245700.0 25365.0 27421.0 25957.0 42221.0 33302.0 38837.0 29200.0 41478.0 33237.0 37295.0 True False 33430.54237522471 36284.30200311898 25612.793219997486 32487.600757947457 28678.592134362956 36408.51625053141 31798.74343210456 35068.52816961929 34993.83996531966 35989.313401714506 0.9289019215807574 1.0081965609655232 0.7116777398364402 0.9027013212316457 0.7968641083604759 1.0116479812809358 0.8835607136253311 0.9744150375469138 0.9723397491559975 1.0 15.13528095857257 -6.7705719022253374 24.999793333799726 0.9614916315585189 0.8704222499019867 0.2724911066394212 0.08025627339884667 303.3676505591342 830447.6022315527 0.028366366795553877 0.025366104381040543 1.6960087861171893e-07 6.7705719022253374 -0.09106938165653222 ELFQT(ph)PCTDNPTTDEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELFQTPCTDNPTTDEK 16 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ELFQT(0.657)PCT(0.342)DNPT(0.001)T(0.001)DEK 110.57 0.0024171999999999996 0.0 17296.0 16071.0 22593.0 24120.0 25366.0 18110.0 21328.0 17596.0 17571.0 13797.0 True False 20223.871188428497 17666.42267046112 23131.702804429628 22768.634598095086 20395.714391354602 17160.27971916705 19307.657438651804 17134.12364450309 17827.942633933868 16298.28688300809 1.2408587070284705 1.083943533285047 1.4192720357957234 1.3969955714690916 1.2514023429430683 1.052888554628256 1.1846433663393885 1.0512837188039934 1.0938537750566002 1.0 13.992432709939887 -6.6898202912077505 5.4363236050783765 1.0866469285434845 1.284920200496873 0.5231414130785836 0.09639864148334382 0.18809854004461896 10.032335219297527 0.03454547955187506 0.034167618319673354 2.0425829800091953e-07 6.6898202912077505 0.1982732719533884 ELFQT(ph)PCTDNPTTDEK ddPTM_PC-9_Lapatinib_30min_R1 2 ELFQTPCTDNPTTDEK 16 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ELFQT(0.644)PCT(0.062)DNPT(0.266)T(0.028)DEK;ELFQT(0.916)PCT(0.078)DNPT(0.005)T(0.001)DEK 201.57 1.1759e-50 4886300.0 88391.0 104873.0 135796.0 102677.0 84836.0 89564.0 93465.0 76380.0 90593.0 63148.0 True False 87130.52813107567 104630.17301187768 124631.37706771908 110228.20910043083 79846.1132739933 85733.5565038814 98304.16037224261 79928.89363889882 80389.46235341791 74063.04766057902 1.1764372501977391 1.4127176279780396 1.682774082412702 1.4883023664593427 1.0780830089509317 1.1575753255089738 1.327303742923966 1.0792007102543524 1.0854193135803971 1.0 16.176466296522378 -6.2585207547629125 24.752555804291077 1.1373412993470902 1.4554418493753218 0.5501830425349188 0.140489944949885 186.1714759771354 1578899.8334584665 0.044558658726008706 0.05499281647978982 5.514158498049223e-07 6.2585207547629125 0.3181005500282317 ELFQT(ph)PDHTEESTTDDK ddPTM_PC-9_AZD4547_30min_R2 2 ELFQTPDHTEESTTDDK 17 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ELFQT(1)PDHTEESTTDDK;ELFQT(1)PDHTEESTTDDK 119.46 0.00020704 4328700.0 33298.0 50748.0 36252.0 36272.0 31381.0 44624.0 37196.0 49707.0 44474.0 38549.0 True False 43886.071358574125 67151.29856877147 35771.27479336401 27910.050796813674 27024.289825489275 41833.654225705206 40506.37194180008 42025.925303227436 46824.8048445295 37199.411243402414 1.1797517727208018 1.805171004707265 0.9616086276018229 0.7502820572667994 0.7264709016135902 1.1245783959315945 1.0888981999408438 1.129747055087627 1.2587512350167698 1.0 15.182992167470248 -5.2835980998416305 24.744585243927748 0.9978923222079417 1.4924614001611172 0.4623029375733245 0.21015245283630224 535.968292562961 598513.7154545143 0.057273005197477696 0.11938241514535454 5.2047742839811645e-06 5.2835980998416305 0.4945690779531755 ELFQT(ph)PDHTEESTTDDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELFQTPDHTEESTTDDK 17 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ELFQT(1)PDHTEESTTDDK 82.03399999999999 0.0098884 2350800.0 12326.0 18396.0 14128.0 10540.0 12667.0 9227.1 8627.3 7042.6 9097.5 8076.6 True False 14412.548350402973 20222.23330507141 14464.865100738363 9949.477971141054 10184.992280820341 8743.21463261879 7810.059687756972 6857.739212251506 9230.533726720925 9540.823645669581 1.5106188821490882 2.1195479610662273 1.5161023448225794 1.042832185212537 1.0675170885737038 0.9164004028716313 0.8185938633612442 0.7187785318057018 0.9674776591128491 1.0 13.219898102070093 -5.7046003386253235 2.4025397133741797 0.9029074169771405 1.8259590910649588 0.8285586685139164 0.1669308290527237 0.10318720260115859 1.2094002748010693 0.04822623941748341 0.09385934945383749 1.9742387021128062e-06 5.7046003386253235 0.9230516740878183 ELFQT(ph)PDHTEESTTDDK ddPTM_PC-9_Lapatinib_30min_R1 3 ELFQTPDHTEESTTDDK 17 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ELFQT(1)PDHTEESTTDDK;ELFQT(1)PDHTEESTTDDK;ELFQT(1)PDHTEESTTDDK 146.15 0.0001961 5719600.0 14119.0 31642.8 23738.2 24351.1 27568.1 23406.4 25908.6 24750.0 21722.3 20155.1 True False 13917.660470892512 31569.533040727827 21786.53682810188 26141.96112688828 25946.598558969974 22405.362834983345 27250.020536246586 25899.97535431718 19275.705828040245 23638.882180017383 0.5887613621027099 1.3354917884998152 0.9216398923684579 1.1058882111179869 1.0976237523153007 0.9478182032618798 1.1527626530192616 1.095651442275522 0.815423744712199 1.0 14.528874195459377 -4.737102447003902 24.959310171344313 1.0543213290421227 0.5887592461251951 0.5126355093891477 0.13563191248042802 1746.5600641586984 1791131.3281150137 0.03154923695928577 2.064363475929914 1.8318822433037746e-05 4.737102447003902 -0.4655620829169276 ELFQT(ph)PDHTEESTTDDKTTK ddPTM_PC-9_Lapatinib_30min_R1 1 ELFQTPDHTEESTTDDKTTK 20 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ELFQT(0.924)PDHT(0.042)EES(0.013)T(0.02)T(0.002)DDKTTK 84.947 0.00056453 6056100.0 53416.0 53216.0 63562.0 45604.0 44741.0 53209.0 41586.0 39073.0 52430.0 31201.0 True False 52654.278044705316 53092.78162158129 58336.1777164154 48957.870290484316 42109.42234419038 50933.37510623714 43739.119598139245 40888.474222999364 46524.781287623766 36594.051277280814 1.4388753419437708 1.45085826161433 1.5941437386746256 1.3378641768718158 1.150717695210034 1.3918484925406114 1.1952521809274066 1.1173530340540545 1.2713755286370378 1.0 15.159321522859623 -6.364898725143518 0.2402525132527274 0.9850559767115782 1.6898840782188775 0.6587054724759096 0.10044305516796168 3.00947280450551 0.3109922005276283 0.2012207160763805 0.652685129814242 4.316197162102988e-07 6.364898725143518 0.7048281015072994 ELFQT(ph)PGHTEEAVAAGK ddPTM_PC-9_AZD4547_30min_R2 4 ELFQTPGHTEEAVAAGK 17 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ELFQT(1)PGHTEEAVAAGK;ELFQT(1)PGHTEEAVAAGK;ELFQT(1)PGHTEEAVAAGK;ELFQT(0.996)PGHT(0.004)EEAVAAGK 116.43 0.00029332 28705100.0 129579.0 128322.0 147800.0 192662.0 187671.0 186941.0 128256.0 197955.0 162357.0 174958.0 True False 170782.42658936468 169799.57702652123 145840.0754291956 148246.75249822764 161616.1210872632 175251.5497178098 139670.53553520542 167365.6033033651 170938.85956161542 168832.7736730708 1.0115478344273914 1.0057263961991323 0.8638137741644969 0.878068572072943 0.9572556179182249 1.038018542875854 0.8272714621490767 0.9913099196454194 1.0124743901478683 1.0 17.365235460390103 -7.976617827367499 24.999797047344487 1.0047890132089794 0.939520389790553 0.1600321934524076 0.06463532433378648 410.44562992354673 438840.8817343564 0.03655223813141726 0.017557361094946294 1.0553151494156535e-08 7.976617827367499 -0.06526862341842643 ELFQT(ph)PGHTEEAVAAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELFQTPGHTEEAVAAGK 17 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ELFQT(0.991)PGHT(0.009)EEAVAAGK;ELFQT(0.999)PGHT(0.001)EEAVAAGK 85.51799999999999 0.014777 4897500.0 72521.0 64994.0 68991.0 65435.0 74713.0 59606.0 57938.0 44957.0 54566.0 43107.0 True False 84797.3729449597 71446.1747896179 70636.00708982459 61768.889093132326 60073.52398175817 56480.15642963401 52449.69320520484 43776.92638587889 55363.92452127002 50921.95786517574 1.6652418033390368 1.4030523920306324 1.3871424047921534 1.2130108833732516 1.179717483385315 1.1091513130578072 1.0300015043426656 0.859686630702329 1.0872308693993094 1.0 15.636000269096623 -4.772054663858394 0.41364618160324995 0.9541167788997851 2.138414429102092 0.9058411206119046 0.06851377499489474 1.5224112864670032 0.20367633363627613 0.054357437745100164 0.9012324168628506 1.6902281723006626e-05 4.772054663858394 1.184297650202307 ELFQT(ph)PGHTEEAVAAGK ddPTM_PC-9_Lapatinib_30min_R1 4 ELFQTPGHTEEAVAAGK 17 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ELFQT(0.999)PGHT(0.001)EEAVAAGK;ELFQT(1)PGHTEEAVAAGK;ELFQT(1)PGHTEEAVAAGK;ELFQT(0.996)PGHT(0.004)EEAVAAGK 159.04 1.7338e-17 15729100.0 160517.0 151005.0 182716.0 147557.0 135357.0 137941.0 122819.0 99104.0 128286.0 88797.5 True False 158227.99814478704 150655.35720021927 167693.79578415686 158408.83401572207 127395.56738210085 132041.58498617643 129177.96686201761 103708.73363693929 113837.0797685314 104146.02955976853 1.51928977814734 1.4465780197003038 1.6101794422025353 1.5210261465110637 1.2232397905192305 1.2678503976034812 1.2403542161718557 0.9958011272760208 1.0930525172176753 1.0 16.66824831387663 -6.861959847128376 0.7425496201261741 1.018202171231304 1.547490339441421 0.8632301021831337 0.07843426759763505 0.24554153457388905 0.2920816657015006 0.060664181736849156 0.054226207626651236 1.374169018490774e-07 6.861959847128376 0.5292881682101169 ELFQT(ph)PGHTEELVAAGK ddPTM_PC-9_AZD4547_30min_R2 1 ELFQTPGHTEELVAAGK 17 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ELFQT(1)PGHTEELVAAGK 142.85 0.0002364 8874100.0 54661.0 62055.0 63227.0 66829.0 68480.0 72673.0 60474.0 89391.0 69393.0 73583.0 True False 72042.06098057008 82113.06519833527 62388.5686682121 51422.606547757576 58972.734050842984 68128.74582163591 65856.0688463388 75577.67495082782 73060.97231138273 71006.88156692211 1.0145785787349688 1.1564099617717458 0.8786270751717568 0.724191872858029 0.830521391018457 0.9594668054451366 0.9274603727565645 1.0643711325302725 1.0289280517484027 1.0 16.115671228411486 -7.750104843932476 23.397725093186526 1.0349871825915622 0.9239609258110574 0.16201486336182636 0.10785872436225574 192.4416486386467 397258.8892624207 0.058740481832970856 0.03345969091755455 1.7778501637295244e-08 7.750104843932476 -0.11102625678050482 ELFQT(ph)PGHTEELVAAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ELFQTPGHTEELVAAGK 17 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ELFQT(0.999)PGHT(0.001)EELVAAGK;ELFQT(1)PGHTEELVAAGK;ELFQT(0.998)PGHT(0.002)EELVAAGK 97.08 0.0031228000000000002 15317200.0 123140.0 123897.0 120000.0 115141.0 128410.0 85867.0 104901.0 95664.0 76743.0 70868.0 True False 143985.16987413767 136196.67535325227 122861.25510253436 108690.02306215883 103248.98229889767 81363.98335978558 94964.01786252887 93152.92136438627 77865.2211915078 83715.80740922078 1.7199281035456941 1.6268931706946788 1.4675992372857642 1.2983213854805071 1.2333271994164083 0.9719070493110221 1.1343618463634284 1.1127279810972242 0.9301137216641289 1.0 16.353212441007088 -5.638759218137722 0.6948838272566299 1.0171926530826303 1.8386582837420067 0.93971504539734 0.06436536690707106 0.2767601932186817 0.20894074077551822 0.033551566938814115 0.1524687115139196 2.297422033477562e-06 5.638759218137722 0.8214656306593764 ELFQT(ph)PGHTEELVAAGK ddPTM_PC-9_Lapatinib_30min_R1 2 ELFQTPGHTEELVAAGK 17 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ELFQT(1)PGHTEELVAAGK;ELFQT(1)PGHTEELVAAGK 157.88 5.9181e-05 14513500.0 99569.0 117408.0 143640.0 116567.0 106903.0 111329.0 100537.0 77092.0 97697.0 71140.0 True False 98149.12780128144 117136.14898952575 131830.47366643418 125139.72603611264 100615.17571938458 106567.71819057451 105742.31392868102 80673.97575818257 86693.33506498147 83436.45421190861 1.176333878618645 1.403896535344467 1.5800104991472474 1.4998207584215852 1.2058898795464885 1.2772321067230161 1.2673394971953251 0.9668912290219092 1.0390342672616595 1.0 16.348390228687208 -7.400182291323553 0.9824725995840239 0.9791394957799024 1.40587216953943 0.6374994268809262 0.11888228228863669 0.36975386873477045 0.6734479410505563 0.09951250022812966 0.051024045046035096 3.9794010360338287e-08 7.400182291323553 0.4267326737595276 ELFQT(ph)PGPSEESMTDEK ddPTM_PC-9_AZD4547_30min_R2 1 ELFQTPGPSEESMTDEK 17 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ELFQT(0.913)PGPS(0.086)EES(0.001)MTDEK 150.92 0.00018588 2551600.0 15426.0 20555.0 18264.0 18677.0 18901.0 25199.0 17203.0 22642.0 19465.0 21480.0 True False 20331.147119267353 27199.00177506695 18021.807426514395 14371.30620677351 16276.922405008536 23623.302546467054 18734.033673373127 19143.19916139931 20493.880161414916 20727.991738003147 0.9808546518277402 1.3121870231740644 0.8694430051066078 0.6933284414825797 0.7852628759575427 1.139681202359589 0.9038036057794131 0.9235433612365714 0.9887055350297633 1.0 14.33929272513454 -5.28246029384227 24.821125628448712 0.905604400834169 1.1465208598308663 0.3174933093582114 0.1366289627439295 746.2780238186007 881191.1990145476 0.03698851582720146 0.07712086191025708 5.218428124801061e-06 5.28246029384227 0.24091645899669722 ELFQT(ph)PGTDKPTTDEK ddPTM_PC-9_AZD4547_30min_R2 2 ELFQTPGTDKPTTDEK 16 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ELFQT(0.823)PGT(0.177)DKPTTDEK;ELFQT(0.991)PGT(0.009)DKPTTDEK 77.74600000000001 0.0074653 17648000.0 72065.0 85488.0 82393.0 87112.0 82846.0 85232.0 71771.0 90631.0 96952.0 85597.0 True False 94980.17095488166 113120.32419104461 81300.41498537015 67029.67426698364 71344.26292605339 79902.42956627175 78158.47996114996 76626.06144319335 102076.68478856917 82600.27508369918 1.1498771748476369 1.3694908894240285 0.9842632473437665 0.8114945646253867 0.8637291201967544 0.9673385407652252 0.946225419733187 0.9276731992181366 1.2357910997891286 1.0 16.33385896580952 -5.333435724871251 6.792752523210305 0.9532731742185343 1.2585428765463915 0.5000822244002123 0.11651892176283925 0.17298795362808614 13.712780342647338 0.030717232483448577 0.06486722013580928 4.640494637350945e-06 5.333435724871251 0.3052697023278572 ELFQT(ph)PGTDKPTTDEK ddPTM_PC-9_Lapatinib_30min_R1 1 ELFQTPGTDKPTTDEK 16 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ELFQT(0.982)PGT(0.018)DKPTTDEK 89.557 0.0026859 7741200.0 32486.0 44414.0 37748.0 37028.0 31235.0 27936.0 27002.0 31314.0 27356.0 18528.0 True False 32022.74368279721 44311.16211178802 34644.505151493795 39751.16264178701 29397.81871037274 26741.24240199669 28400.031438199283 32768.962757377296 24274.879208549235 21730.54011299184 1.4736285207955813 2.039119224896583 1.5942772232698073 1.8292763288484184 1.3528342396237512 1.2305834214405535 1.306917881034168 1.5079681677026526 1.117085865437658 1.0 14.407436412727229 -6.3495205201116685 4.58756565778585 1.2717972718487256 1.7455781680057696 0.615284583219289 0.1867781621412045 0.15128543896112878 5.568154380108957 0.05576767770177564 0.06389460180267033 4.4717702248684723e-07 6.3495205201116685 0.473780896157044 ELFQT(ph)PICTDKPTTHEK ddPTM_PC-9_Lapatinib_30min_R1 2 ELFQTPICTDKPTTHEK 17 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ELFQT(0.996)PICT(0.003)DKPTTHEK;ELFQT(0.998)PICT(0.002)DKPTTHEK 56.081 0.031241 10698100.0 81194.0 106696.0 111613.0 92866.0 95131.0 87813.0 89276.0 85767.0 86351.0 66623.0 True False 80036.1586708438 106448.9519673829 102436.60997863935 99695.67543189476 89535.58161474206 84057.44269210094 93898.27444917709 89752.04792782699 76625.24106365816 78138.69678043251 1.0242832548864118 1.3623077470373148 1.310958772021541 1.2758809596228198 1.1458545548351602 1.075746667855236 1.201687234598096 1.1486248379599633 0.9806311625464255 1.0 16.25374957359054 -7.6744583999845295 0.5718403900457543 0.9900637807845235 1.2494754698742774 0.3942173942967848 0.09905042118235985 0.832512599500458 0.5772354834460468 0.09814105598654815 0.0605852352973617 2.116126374148063e-08 7.6744583999845295 0.25941168908975387 ELFQTPCT(ph)DNPTTDEK ddPTM_PC-9_AZD4547_30min_R2 1 ELFQTPCTDNPTTDEK 16 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ELFQT(0.294)PCT(0.677)DNPT(0.029)TDEK 185.14 1.6886e-07 4509000.0 46351.0 45358.0 45573.0 69542.0 61737.0 69154.0 51333.0 64739.0 57684.0 60776.0 True False 61089.65383930775 60019.08647596626 44968.67224313078 53510.16631318963 53165.88320819064 64829.78944792972 55901.53755480222 54735.07510422355 60733.05847577999 58648.250738774695 1.0416278929001193 1.0233738554845806 0.7667521482171027 0.9123915144806173 0.9065212097287764 1.105400223046519 0.9531663238140449 0.9332771977807006 1.035547654205259 1.0 15.839800458167595 ELFQTPDHTEES(ph)TTDDKTTK ddPTM_PC-9_Lapatinib_30min_R1 1 ELFQTPDHTEESTTDDKTTK 20 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ELFQT(0.019)PDHT(0.019)EES(0.32)T(0.32)T(0.32)DDKT(0.002)T(0.001)K 68.26100000000001 0.0024391 7694500.0 46957.0 51924.0 66055.0 42703.0 42222.0 53923.0 43460.0 36784.0 47620.0 34852.0 True False 46287.384569140864 51803.77316820104 60624.212879673745 45843.521073031996 39738.584971645854 51616.838990652424 45710.14614858686 38493.11892659404 42256.534139169235 40876.12176262912 1.1323820013536356 1.2673358169600741 1.483120469004456 1.1215232535818578 0.9721711174658636 1.2627626292532228 1.1182603480347109 0.941701836346575 1.0337706298204188 1.0 15.318970702555902 -6.77579915058851 0.6296610399704735 0.9912685669390582 1.28081778933528 0.36954114362426393 0.12499451576686858 0.9165159461735254 0.7939020143740663 0.10663753609265833 0.11488505693498718 1.6757176707970145e-07 6.77579915058851 0.2895492223962217 ELFQTPGHT(ph)EELVAAGK ddPTM_PC-9_Lapatinib_30min_R1 1 ELFQTPGHTEELVAAGK 17 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ELFQT(0.323)PGHT(0.677)EELVAAGK 82.505 0.010786 2918700.0 12186.0 13973.0 16304.0 12430.0 11711.0 13088.0 10385.0 9222.1 12385.0 7775.3 True False 12012.225405361289 13940.64637699856 14963.548055260011 13344.143665264459 11022.182004711869 12528.25674961815 10922.68448580475 9650.59243293125 10990.07088016823 9119.250245063993 1.3172382687779827 1.5287053214209425 1.6408748146109249 1.4632939448599174 1.2086719531222299 1.3738253050352862 1.1977612404832192 1.0582659948557567 1.2051507070021312 1.0 13.154699500259074 -6.98098048875215 0.7490193486029483 1.0662363358564817 1.5075001372874692 0.6833673569140373 0.10927643489077228 0.4040109829612235 0.4765164016531487 0.08689436859801869 0.06899253908274708 1.044767155697942e-07 6.98098048875215 0.44126380143098753 ELGEYGFHEYTEVK ddPTM_PC-9_Lapatinib_30min_R1 2 ELGEYGFHEYTEVK 14 0 P00352 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ; 139.74 9.026e-05 65357000.0 502870.0 433650.0 519190.0 491740.0 519910.0 425470.0 498100.0 494050.0 436620.0 501570.0 False True 495698.9815849354 432645.9100683774 476504.20233135676 527904.199996552 489329.91598238796 407273.6399190126 523889.1807779817 517005.3666181979 387443.25778757007 588265.7061999841 0.8426447035082135 0.7354600234359014 0.8100152657366816 0.8973907444080857 0.8318178517379655 0.6923293940588094 0.8905655646019977 0.8788636855238322 0.6586194872557413 1.0 19.16610840914577 -11.073605065922639 3.2250617380305546 1.0068347574160628 0.8073400791327899 0.35506774274413144 0.07906704729476402 57747331.0012704 69416616.79656905 3424960.8606654415 0.01942687193594826 8.44102009323482e-12 11.073605065922639 -0.19949467828327283 ELGITALHIK ddPTM_PC-9_AZD4547_30min_R2 2 ELGITALHIK 10 0 P62263;A0A2R8Y811;E5RH77 P62263 RPS14 40S ribosomal protein S14 0 ; 107.55 0.0026383 3669600.0 50284.0 52003.0 70638.0 72889.0 66988.0 68501.0 58318.0 71300.0 59870.0 67670.0 False True 66273.26602782575 68811.95277590887 69701.2939659507 56085.56717382418 57687.87249704843 64217.621641158 63508.189023064195 60282.22331100475 63034.605972972575 65300.89389714503 1.01489064042848 1.0537673938169068 1.0673865211667195 0.858879011092316 0.883416275861586 0.9834110654336021 0.9725470086687555 0.9231454535056571 0.9652946875774462 1.0 15.994815120358696 -5.7403661058123046 24.999972940977226 0.938441666387018 1.0461901505064102 0.548835970984411 0.04332932097575559 184.53093343366012 218913.90420716288 0.012291435383328914 0.021261786650055632 1.8181675157598186e-06 5.7403661058123046 0.1077484841193922 ELGITALHIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELGITALHIK 10 0 P62263;A0A2R8Y811;E5RH77 P62263 RPS14 40S ribosomal protein S14 0 ; 120.27 0.00060415 9828600.0 73332.0 78541.0 85837.0 93530.0 96940.0 84252.0 93983.0 88304.0 72268.0 67326.0 False True 85745.65922697961 86338.031420614 87883.67961863542 88289.81732835108 77945.30288961268 79833.67680283065 85080.24986200365 85986.11356582184 73324.78278237637 79531.67084767728 1.0781322498706667 1.085580505230081 1.1050148787513128 1.1101214948375449 0.9800536322051767 1.0037973042931765 1.0697656537978848 1.0811556283094619 0.9219570266895483 1.0 16.279241859772107 -6.251910391027028 24.808441207324528 1.016245315722031 1.0947959157147353 0.4827063453225392 0.04289366212828497 597.2873039048981 1555017.1472834765 0.013026541435109349 0.016579424025947274 5.598731094763793e-07 6.251910391027028 0.0785505999927043 ELGITALHIK ddPTM_PC-9_Lapatinib_30min_R1 2 ELGITALHIK 10 0 P62263;A0A2R8Y811;E5RH77 P62263 RPS14 40S ribosomal protein S14 0 ; 128.35 0.00023719 17953900.0 107038.0 117596.0 115735.0 113469.0 119010.0 115432.0 121198.0 109744.0 106402.0 114898.0 False True 105511.61849163494 117323.71368707677 106219.71505001941 121813.88878148774 112010.06578266236 110495.24244513469 127473.03941363163 114843.1068801691 94417.88629726764 134757.9662080387 0.7829712889013671 0.8706254404726841 0.7882258692301568 0.9039457347807701 0.8311943919496512 0.8199533248709961 0.9459406593955222 0.8522175728214454 0.7006479019689698 1.0 17.040011034755054 -11.761273855138016 2.367812825860702 1.5936298258765174 0.8382138115695866 0.37188618638674364 0.06483055726889207 5723202.599949326 901043.4807352782 18292903.28032104 0.01596893056473786 1.732711049346132e-12 11.761273855138016 -0.7554160143069307 ELGLPEELVSR ddPTM_PC-9_Lapatinib_30min_R1 1 ELGLPEELVSR 11 0 P49915-2;P49915 P49915-2 GMPS GMP synthase [glutamine-hydrolyzing] 0 110.38 0.008954299999999998 2477000.0 8839.7 8616.3 10088.0 9152.0 12619.0 9724.8 10271.0 9649.4 10307.0 8766.2 False True 8713.644256997559 8596.349486733896 9258.603580806119 9825.068610177012 11876.775229908559 9308.892973616023 10802.78212361103 10097.74635086659 9146.117122478321 10281.425989772726 0.8475132015408474 0.8361047869512428 0.9005174564322067 0.9556134158773629 1.1551680906639583 0.9054087422188212 1.0507085431881642 0.9821348090149316 0.8895767115939234 1.0 13.327752753585104 -5.6784945210679 2.6849524027882667 0.9978750576800118 0.8458524470794171 0.43658752824429603 0.07013753242829887 0.24615024167535393 3.580321582379166 0.020116316919781697 0.03868580021676243 2.0965512296019393e-06 5.6784945210679 -0.15202261060059474 ELGNDAYK ddPTM_PC-9_Lapatinib_30min_R1 1 ELGNDAYK 8 0 P31948-2;P31948;P31948-3 P31948-2 STIP1 Stress-induced-phosphoprotein 1 0 96.948 0.027476 9120200.0 73496.0 68014.0 73994.0 58803.0 69125.0 64030.0 63205.0 65831.0 66859.0 58759.0 False True 72447.93356248424 67856.5177617678 67910.49894509981 63127.56878105762 65059.20340497892 61291.586161220155 66477.44563555981 68889.74858788078 59328.63536351775 68915.4148585541 1.051258759904159 0.9846348295376348 0.985418125748545 0.9160152182298288 0.9440442829591916 0.8893741158929171 0.964623745964555 0.9996275685095127 0.8608906365185091 1.0 16.0725390976405 -4.795430902041029 1.1620942887789651 0.9393375689305152 1.0983638432229819 0.3822040464059768 0.042886420297023754 1.614582737576095 1.854682532333338 0.012888586666480753 0.31291691752859907 1.6016554577515147e-05 4.795430902041029 0.15902627429246663 ELGPYS(ph)SK ddPTM_PC-9_Lapatinib_30min_R1 1 ELGPYSSK 8 0 P17655 P17655 CAPN2 Calpain-2 catalytic subunit 1 ELGPYS(0.5)S(0.5)K 78.098 0.022608 5758100.0 32599.0 34279.0 29975.0 26682.0 32610.0 33559.0 31490.0 41389.0 38448.0 30713.0 True False 32134.13228207557 34199.62908159548 27510.571206846103 28644.28328854274 30691.943913726762 32123.75979984988 33120.39811824663 43312.08403797306 34117.581364611084 36021.701127499924 0.8920770334620183 0.949417379277698 0.7637221548608042 0.7951951849013298 0.8520403799113118 0.8917890825351873 0.9194568019154886 1.2023886346918653 0.947139649064625 1.0 15.136578693782452 -7.556507331191546 10.420901568962396 1.0573098684516686 0.8584790764448514 0.5519409867817662 0.0774626221120739 0.3398294313785193 102.15133402957271 0.03636169140501272 0.021023668875696882 2.7764679770081302e-08 7.556507331191546 -0.1988307920068172 ELHDAMK ddPTM_PC-9_AZD4547_30min_R2 1 ELHDAMK 7 0 P13928-3;A0A087WUP0;B4DTF2;A0A075B765;A0A087WTN9;A0A075B752;P13928-2;Q5VT79-2;Q5VT79;P13928 P13928-3 ANXA8;ANXA8L1;ANXA8L2 Annexin A8;Annexin;Annexin A8-like protein 2 0 69.998 0.030611000000000003 2060800.0 27231.0 24799.0 26836.0 36530.0 30597.0 32249.0 26820.0 31276.0 34442.0 32477.0 False True 35889.89156001357 32814.7917791236 26480.137105669106 28108.57288287394 26349.134692664185 30232.464931982067 29206.9280427755 26443.012850981548 36262.533805263425 31339.99011522946 1.1451787772764204 1.0470581406845267 0.8449312526362687 0.8968915682336086 0.8407512126131782 0.9646609593948405 0.9319380106818409 0.8437466876587093 1.1570690887883175 1.0 14.935717104327662 -5.025011514325396 4.368797630388405 0.9258631881440422 1.1302389193629085 0.35402679692620853 0.09077202460760363 0.18489660601548732 8.477047658833493 0.022435447257433582 0.07917967210747902 9.44035847001699e-06 5.025011514325396 0.20437573121886632 ELHDAMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELHDAMK 7 0 P13928-3;A0A087WUP0;B4DTF2;A0A075B765;A0A087WTN9;A0A075B752;P13928-2;Q5VT79-2;Q5VT79;P13928 P13928-3 ANXA8;ANXA8L1;ANXA8L2 Annexin A8;Annexin;Annexin A8-like protein 2 0 ; 66.429 0.036832 4793100.0 56312.0 54021.0 63344.0 67134.0 82719.0 67451.0 64984.0 56360.0 65944.0 60418.0 False True 65844.50938730272 59383.84786764856 64854.36119345779 63372.699631364674 66510.8057533101 63913.750819300745 58828.245076582396 54880.609718356136 66908.3062462088 71371.30513137513 0.9225627759797991 0.8320409408002147 0.9086895787330578 0.8879296730627637 0.9318984097443898 0.8955104674301939 0.8242562605278917 0.768945020934336 0.9374678818475973 1.0 16.123056534117815 -7.110472480095189 16.530930126507613 0.8628965600188238 0.8953349321481255 0.0 0.06402826167559585 7.028391978287201 1031.369696569799 0.023655267746006046 0.01832339162771036 7.754030767095954e-08 7.110472480095189 0.032438372129301785 ELHDAMK ddPTM_PC-9_Lapatinib_30min_R1 2 ELHDAMK 7 0 P13928-3;A0A087WUP0;B4DTF2;A0A075B765;A0A087WTN9;A0A075B752;P13928-2;Q5VT79-2;Q5VT79;P13928 P13928-3 ANXA8;ANXA8L1;ANXA8L2 Annexin A8;Annexin;Annexin A8-like protein 2 0 ; 66.682 0.036391 3551600.0 64241.0 61088.0 60860.0 57871.0 67681.0 58702.0 56489.0 64479.0 73108.0 50883.0 False True 63324.91155964339 60946.55448923553 55856.325726393814 62127.02639199671 63700.13664596571 56191.45230104553 59413.724017200184 67474.92973216226 64873.80717863046 59678.05875266434 1.061108770680585 1.0212556467667366 0.9359608354201048 1.0410363153647828 1.067396258815503 0.9415764097476922 0.9955706545925078 1.1306488706647118 1.087062959730307 1.0 15.8649129869681 -7.742367803095241 24.960469242377165 1.0816419507302302 1.0076515317990042 0.23626222016045384 0.051453505320444404 285.6450351138153 373847.3579538189 0.024412019702758057 0.01406365458063704 1.8098067218509466e-08 7.742367803095241 -0.07399041893122593 ELHINLIPNK ddPTM_PC-9_AZD4547_30min_R2 2 ELHINLIPNK 10 0 P07900;P07900-2;G3V2J8;Q14568 P07900 HSP90AA1;HSP90AA2P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2 0 ; 81.865 0.013175999999999998 6149200.0 100436.0 124766.0 140680.0 111661.0 115720.0 138628.0 130761.0 156677.0 131198.0 124920.0 False True 132372.5588014223 165094.16956789105 138814.4912813208 85919.28159525276 99654.2754725984 129959.56924527297 142398.47568237747 132466.16972928855 138132.8584339746 120546.58882268897 1.0981029002498617 1.369546589250458 1.1515422596113603 0.7127475147524146 0.8266868141675837 1.0780858298398595 1.1812733738308454 1.0988794541845726 1.1458877416859397 1.0 16.879231301169703 -5.531320766426362 24.997101570264313 1.0069191268898021 1.2405047268183025 0.2877442962356168 0.14806473633311348 236.41069587944338 700017.3584208197 0.044346912407171174 0.07696211470808854 2.942247710479926e-06 5.531320766426362 0.23358559992850036 ELHINLIPNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELHINLIPNK 10 0 P07900;P07900-2;G3V2J8;Q14568 P07900 HSP90AA1;HSP90AA2P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2 0 ; 93.05799999999999 0.0059056 10409900.0 294920.0 432650.0 364080.0 297650.0 343140.0 212630.0 306320.0 231981.0 218524.0 200388.0 False True 344844.13106448436 475600.6327157603 372761.04798108916 280973.63549432065 275904.180251101 201479.30848627802 277303.15203525044 225891.74455418705 221719.50009320807 236716.7581294646 1.4567795444202687 2.00915489242906 1.5747133871156662 1.1869613191502528 1.165545618448374 0.8511408743443732 1.1714555159782494 0.9542701849213516 0.9366447134762876 1.0 17.852802318297528 -5.806598622225411 2.1146982025923062 1.011726853045072 1.7517211001299575 0.7902089963705257 0.15500673307658397 0.12622983387616996 1.152725448265107 0.04535708895755398 0.08397209844205311 1.560994517613697e-06 5.806598622225411 0.7399942470848855 ELHINLIPNK ddPTM_PC-9_Lapatinib_30min_R1 2 ELHINLIPNK 10 0 P07900;P07900-2;G3V2J8;Q14568 P07900 HSP90AA1;HSP90AA2P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2 0 ; 95.48299999999999 0.0049512 14396100.0 155598.0 198110.0 210943.0 192281.0 214027.0 202477.0 244910.0 233239.0 188605.0 224007.0 False True 153379.14398682144 197651.2884668418 193600.08080352776 206421.98617061283 201438.35265327175 193817.53070694016 257590.24144616688 244076.13542083133 167362.3188013022 262726.3114794343 0.5837981857360627 0.7523086947548211 0.736888816781803 0.7856920953528902 0.7667231786529304 0.7377164838022392 0.9804508729851008 0.929012910988693 0.6370215371991891 1.0 18.003201164973284 -2.3825016202047515 0.1421754698808248 0.9916493845089981 1.1940016160939724e-19 0.41166171664898543 0.10092925980038596 61.63342504303162 0.7311618215941855 0.4467433436689554 11.956348476321086 0.00414475037769897 2.3825016202047515 -0.9916493845089981 ELHIQGNR ddPTM_PC-9_AZD4547_30min_R2 2 ELHIQGNR 8 0 Q15404-2;Q15404 Q15404-2 RSU1 Ras suppressor protein 1 0 ; 90.37 0.010178 0.0 23768.0 24446.0 32826.0 41233.0 35789.0 30327.0 28826.0 32215.0 30031.0 30811.0 False True 31325.729594888282 32347.69143241484 32390.70579187262 31727.368893499624 30820.31511310778 28430.647895817536 31391.45815663857 27236.911977054955 31618.377350498376 29732.31626813852 1.0535919674868144 1.0879640570445224 1.0894107778135962 1.067100477721577 1.0365931411181433 0.956220418194735 1.0558026449583415 0.9160709758170551 1.0634347174754422 1.0 14.859744238973569 -6.439111007504479 3.145461891424104 0.9964497520818685 1.0767055649709614 0.4243277051880525 0.041491046652650215 0.22801133894250233 4.35747847220485 0.012791400809008957 0.01432825671327622 3.638220297933354e-07 6.439111007504479 0.08025581288909289 ELHIQGNR ddPTM_PC-9_Lapatinib_30min_R1 2 ELHIQGNR 8 0 Q15404-2;Q15404 Q15404-2 RSU1 Ras suppressor protein 1 0 ; 86.794 0.010247 3817500.0 36685.0 32396.0 35552.0 28532.0 34134.0 37787.0 29907.0 29648.0 36031.0 29940.0 False True 36161.86517279494 32320.989052404326 32629.051794688658 30630.338459961815 32126.305230026017 36170.93809579928 31455.438123925138 31025.55431534527 31972.80935674942 35115.08910745771 1.0298098649880663 0.9204302160104736 0.9292031609214664 0.872284229899806 0.9148860517401638 1.030068241749594 0.8957812417239364 0.8835391025323098 0.9105148290783938 1.0 15.099803475683773 ELHPQLLS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ELHPQLLSPTK 11 0 E9PK89;Q8TBN0 E9PK89 RAB3IL1 Guanine nucleotide exchange factor for Rab-3A 1 ELHPQLLS(0.758)PT(0.242)K;ELHPQLLS(0.986)PT(0.014)K;ELHPQLLS(0.95)PT(0.05)K;ELHPQLLS(0.94)PT(0.06)K 90.229 0.009284 19603800.0 205044.0 268360.0 306178.0 445209.0 327741.0 457061.0 377105.0 333124.0 467456.0 345370.0 True False 239753.8993963998 295001.0072705453 313478.4447065307 420265.3831170536 263522.50375845435 433091.91655009484 341382.88439622964 324379.84797405417 474291.65966013365 407982.8470525845 0.5876568123598053 0.723072083548951 0.7683618244522098 1.030105520742361 0.6459156448910441 1.0615444244259467 0.8367579344634288 0.7950820734682631 1.1625284324735414 1.0 18.6381489722405 -3.8209638301401494 0.364790846547286 0.9726185942660873 1.2911613011350268e-30 0.42052478051008646 0.13882254983431247 13.245774381156618 0.8146268245795015 0.11624301585809417 6.49198720351716 0.00015102059251889804 3.8209638301401494 -0.9726185942660873 ELHPQLLSPT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 ELHPQLLSPTK 11 0 E9PK89;Q8TBN0 E9PK89 RAB3IL1 Guanine nucleotide exchange factor for Rab-3A 1 ELHPQLLS(0.393)PT(0.607)K 110.25 0.0041095 12785000.0 155180.0 107900.0 155650.0 122140.0 172790.0 163780.0 146840.0 152350.0 177200.0 137650.0 True False 152967.10474347294 107650.1641793561 142853.05782637495 131122.5830470958 162626.83191821072 156775.5111898273 154442.65670636203 159428.73718101863 157241.8700012764 161442.61909290456 0.9475013822430974 0.6668013984424225 0.8848534459427224 0.8121931109878697 1.0073351933458456 0.9710912277730609 0.9566411742706287 0.9875257108488372 0.9739799247854697 1.0 17.300661959108282 -6.257289051176542 24.82474932996995 0.9802488923981637 0.8204073381862804 0.5558282622003068 0.06769466119847065 229.30822148153703 1371581.8936465883 0.019044784625114723 0.023694212834889018 5.5298194132232e-07 6.257289051176542 -0.15984155421188329 ELHYLPFPS(ph)P ddPTM_PC-9_AZD4547_30min_R2 5 ELHYLPFPSP 10 0 Q8N565 Q8N565 MREG Melanoregulin 1 ELHYLPFPS(1)P;ELHYLPFPS(1)P;ELHYLPFPS(1)P;ELHYLPFPS(1)P;ELHYLPFPS(1)P 118.03 0.00090707 3640930.0 49201.100000000006 62406.8 81324.5 79982.8 74242.0 55366.6 74917.1 76625.0 57577.399999999994 53479.1 True False 64846.026353545014 82578.57766851134 80246.08399351564 61544.00118194171 63934.77981020285 51904.51774948303 81584.5767663468 64784.366917331565 60620.823817408236 51606.812986771176 1.2565400302895582 1.6001487572906201 1.5549513591177548 1.1925557425473614 1.2388825449576164 1.0057687104760404 1.5808877170396103 1.2553452377293344 1.1746670702751534 1.0 15.655273918325832 -6.8323808773057735 0.03996540348257267 4.67962702686538e-12 2.606177273324884 0.2825359451121203 0.17837288131411988 198.09187756287943 3.2989854134080856 95.93845310673744 117.55401031950845 1.4710218468616603e-07 6.8323808773057735 2.606177273320204 ELHYLPFPS(ph)P ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ELHYLPFPSP 10 0 Q8N565 Q8N565 MREG Melanoregulin 1 ELHYLPFPS(1)P;ELHYLPFPS(1)P;ELHYLPFPS(1)P;ELHYLPFPS(1)P 115.7 0.0019949 4657600.0 49202.7 38761.6 44760.1 44132.0 62640.0 41877.1 49753.1 41097.5 41667.9 37135.1 True False 57531.74531237809 42609.5954815099 45827.350537624516 41659.42711787446 50366.14166500243 39680.991155578704 45040.126186749214 40018.734171400625 42277.214209577854 43867.399668710124 1.3114920361558269 0.9713271313845988 1.0446789844785898 0.9496671202872649 1.148145138425603 0.9045667501436718 1.0267334404796182 0.9122659303634383 0.9637501773266374 1.0 15.42086156969408 -4.7591680317013925 24.99795046458266 0.9921706531067296 1.3114924496362448 0.6700569218294561 0.06741587146646516 34.84616181409681 383421.9348017885 0.016074696857626615 0.10399668429161045 1.7411330859682127e-05 4.7591680317013925 0.3193217965295152 ELHYLPFPS(ph)P ddPTM_PC-9_Lapatinib_30min_R1 4 ELHYLPFPSP 10 0 Q8N565 Q8N565 MREG Melanoregulin 1 ELHYLPFPS(1)P;ELHYLPFPS(1)P;ELHYLPFPS(1)P;ELHYLPFPS(1)P 107.55 0.0033614000000000005 3870810.0 54106.0 50923.7 32111.1 21907.5 32923.3 32484.3 23400.399999999998 21983.9 40106.5 16717.1 True False 53334.43851817482 50805.78930139281 29471.04931043054 23518.65063127764 30986.816223698268 31095.022213601816 24611.95821296345 23005.35225017267 35589.283629831836 19606.628460864416 2.7202248782666745 2.5912557787690584 1.5031166306464105 1.1995254909951383 1.5804255323932488 1.5859443797626234 1.2552876320418813 1.1733456517571206 1.8151659119195027 1.0 14.259053851796462 -5.263077684915548 4.110172073720482 1.3893241350022105 2.69349596147649 0.8352928791250099 0.22585323751535322 0.07116162258069011 2.9442756753570096 0.05750972197434773 0.1485434195003744 5.456602467686812e-06 5.263077684915548 1.3041718264742794 ELILFSNSDNER ddPTM_PC-9_Lapatinib_30min_R1 1 ELILFSNSDNER 12 0 Q02880;Q02880-2;E9PCY5;P11388;P11388-2;P11388-3;P11388-4 Q02880;P11388 TOP2B;TOP2A DNA topoisomerase 2-beta;DNA topoisomerase 2;DNA topoisomerase 2-alpha 0 130.44 0.00067282 3336400.0 17524.0 15567.0 14088.0 15737.0 18285.0 16604.0 14636.0 13337.0 14980.0 13722.0 False True 17274.10454649199 15530.955567933632 12929.739021252637 16894.351477093056 17209.51224969315 15893.885625814457 15393.780465502 13956.685709112238 13292.794653606794 16093.829416584324 1.0733371219090604 0.9650254868446249 0.8033972951104376 1.0497409311225714 1.0693236397770651 0.9875763694522679 0.9565020273943665 0.8672072598663306 0.825955980365299 1.0 13.974220025870823 -7.613005928492293 4.091988162425949 0.8855392188023805 0.9869368946355155 0.1956489589592426 0.08334041647611642 0.35951640485564346 11.26963128602989 0.04388291717045805 0.024179086811969536 2.4377775403866308e-08 7.613005928492293 0.10139767583313497 ELILGSETPS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 2 ELILGSETPSSPR 13 0 R4GNJ5;A0A590TQL1;Q96AP0-2;Q96AP0 R4GNJ5 ACD Adrenocortical dysplasia protein homolog 1 ELILGS(0.011)ET(0.09)PS(0.729)S(0.17)PR;ELILGS(0.002)ET(0.019)PS(0.607)S(0.371)PR 119.62 0.00022521 5994600.0 33181.0 33575.0 45009.0 54385.0 57833.0 50863.0 40472.0 53012.0 39587.0 42045.0 True False 43731.86779232529 44427.46215508988 44412.151251641844 41847.37848987405 49803.88622024538 47682.528569425536 44073.929595347116 44820.213494572 41679.48800153771 40573.01734750199 1.0778559410005966 1.0950002011084148 1.0946228344630677 1.031409079868459 1.2275125064937207 1.175227569619277 1.086286711630548 1.1046803127973794 1.0272710960725193 1.0 15.308232976902778 -8.319918631450399 2.2116918362027995 0.9991019275388049 1.114743610795362 0.37462880688535705 0.05126516992967921 0.3425098416087239 3.169129635919506 0.05172683575898666 0.014711769381851739 4.787197759051572e-09 8.319918631450399 0.11564168325655722 ELILGSETPS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELILGSETPSSPR 13 0 R4GNJ5;A0A590TQL1;Q96AP0-2;Q96AP0 R4GNJ5 ACD Adrenocortical dysplasia protein homolog 1 ELILGS(0.002)ET(0.015)PS(0.7)S(0.282)PR;ELILGSET(0.003)PS(0.766)S(0.231)PR 151.99 0.00013696 9196400.0 48202.0 44194.0 56340.0 55559.0 60299.0 55550.0 57007.0 52324.0 46289.0 43973.0 True False 56361.64656710401 48581.288252029015 57683.35927063987 52446.209354708284 48483.843809993305 52636.86020981393 51606.8842650611 50950.55044186063 46965.8890548156 51944.956809923526 1.0850263438150887 0.9352455220975 1.1104708293764542 1.00964968642902 0.9333696048185179 1.0133199340683294 0.9934917157386519 0.9808565368202804 0.9041472346713603 1.0 15.664696068265174 -6.0048930014380035 24.98381555324269 0.9730110217873211 1.037299508053288 0.28083991428540056 0.0521486304382367 303.5460914266128 1549937.3982123288 0.014278130442072452 0.02055874056857152 9.88796677743942e-07 6.0048930014380035 0.06428848626596695 ELILGSETPS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 ELILGSETPSSPR 13 0 R4GNJ5;A0A590TQL1;Q96AP0-2;Q96AP0 R4GNJ5 ACD Adrenocortical dysplasia protein homolog 1 ELILGS(0.041)ET(0.234)PS(0.589)S(0.136)PR 73.881 0.020259 2824800.0 18934.0 18262.0 20002.0 16272.0 19181.0 19008.0 19189.0 18512.0 20661.0 15737.0 True False 18663.997687929652 18219.715461013944 18357.512769952828 17468.69716180074 18052.81129129692 18195.07214981218 20182.51252750191 19372.135101378553 18333.940610024696 18457.11948176558 1.0112085857367101 0.9871375367653562 0.9946033446924826 0.9464476393003071 0.9780947297400284 0.9858023711548116 1.0934811657605024 1.049575212454844 0.9933262136671663 1.0 14.171889795283061 -7.047503604800725 24.587221363867027 1.0384290794659414 0.9822280456962142 0.3994203075871364 0.02996744191520802 318.37256032435397 164784.21674181032 0.011579188036847758 0.008969467554205105 8.963887455694132e-08 7.047503604800725 -0.05620103376972718 ELILGSETPSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 ELILGSETPSSPR 13 0 R4GNJ5;A0A590TQL1;Q96AP0-2;Q96AP0 R4GNJ5 ACD Adrenocortical dysplasia protein homolog 1 ELILGSET(0.003)PS(0.088)S(0.909)PR;ELILGSETPS(0.054)S(0.946)PR 182.72 6.5142e-05 17745800.0 61944.0 66239.0 84538.0 106588.0 99384.0 74180.0 70658.0 85811.0 71401.0 78985.0 True False 81640.90348475927 87649.46137575567 83416.97088385206 82015.7833681841 85586.2470927131 69541.51287340482 76946.42511731666 72550.88169061179 75175.11109196952 76219.75919116303 1.0711251826445651 1.149957206712322 1.0944271114087103 1.0760435907765642 1.122887923039201 0.9123816922458541 1.0095338260559328 0.9518644831801487 0.9862942613532342 1.0 16.217877429653562 -6.750695291007594 24.999978902869298 0.9713513165141614 1.1035417402651628 0.7988948323822755 0.0328296262627795 86.49673615115502 201265.37085222118 0.010287470944874397 0.010189642389010104 1.775434721636791e-07 6.750695291007594 0.13219042375100143 ELILGSETPSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELILGSETPSSPR 13 0 R4GNJ5;A0A590TQL1;Q96AP0-2;Q96AP0 R4GNJ5 ACD Adrenocortical dysplasia protein homolog 1 ELILGSET(0.001)PS(0.292)S(0.706)PR;ELILGS(0.002)ET(0.004)PS(0.3)S(0.695)PR 154.72 0.00012102 8580000.0 51660.0 47168.0 55066.0 60128.0 62322.0 56290.0 62784.0 53446.0 54165.0 48047.0 True False 60405.01766849081 51850.52731754777 56378.9822789679 56759.22309760614 50110.45148222035 53338.053307118345 56836.645003203084 52043.09913071793 54957.06065488746 56757.540760157295 1.0642641816308922 0.9135442907340666 0.9933302522251786 1.0000296407741829 0.8828862352224557 0.9397527199515423 1.00139372217306 0.916937175813142 0.9682776934807975 1.0 15.79252445996292 -4.7471509868737725 24.92289689164105 0.9557120315796835 1.064264470303312 0.3845604533619752 0.040528047684312854 761.1277632385471 1327538.5660675995 0.009925234899370135 0.20708811869965577 1.7899834399811803e-05 4.7471509868737725 0.10855243872362841 ELILGSETPSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 ELILGSETPSSPR 13 0 R4GNJ5;A0A590TQL1;Q96AP0-2;Q96AP0 R4GNJ5 ACD Adrenocortical dysplasia protein homolog 1 ELILGS(0.001)ET(0.007)PS(0.187)S(0.805)PR;ELILGSETPS(0.001)S(0.999)PR 202.92 1.2039999999999999e-08 11251100.0 100527.0 79136.0 87795.0 86310.0 81585.0 89849.0 71814.0 74696.0 87920.0 59075.0 True False 99093.4665456061 78952.7654541015 80576.8339985006 92657.52532171972 76786.3307022815 86006.36771824874 75532.17753139934 78166.64885115462 78017.52376135583 69286.03503751052 1.4302083600534834 1.1395191745545483 1.1629592305993177 1.337318916742114 1.1082511888681525 1.2413232720227974 1.0901500928795715 1.1281732142535832 1.126020903333813 1.0 16.080276978486566 -1.5228787455356885 0.09136245890295934 0.8835143597343681 2.053822943549714 0.503145548733311 0.08462471452492942 135.11981167316728 0.8893824736216126 1.4630782793916033 19.80963976695641 0.029999999982360984 1.5228787455356885 1.1703085838153462 ELIPQES(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 ELIPQESPR 9 0 Q96DF8 Q96DF8 DGCR14 Protein DGCR14 1 ELIPQES(1)PR;ELIPQES(1)PR;ELIPQES(1)PR 107.34 0.0025087 33000200.0 69917.0 69740.0 121517.0 134357.0 118714.0 99658.0 93922.0 127471.0 100356.0 105386.0 True False 92149.15163605694 92282.09115996923 119905.60518220263 103383.0694449573 102232.61025280067 93426.36950576676 102280.87604897682 107773.2859421752 105660.61327916547 101696.46821700185 0.9061194872512911 0.9074267059408195 1.179053779196597 1.016584658813879 1.0052719828446235 0.9186786045156633 1.0057465892594022 1.0597544617990717 1.0389801645196257 1.0 16.633910051623452 -5.081621891502814 24.999950032610865 1.0254910944692108 0.9064151984339582 0.3825649884926571 0.061542025813788 90.15508800173276 27612.434472089277 0.016334222093274592 0.04321633659848679 8.28663306383106e-06 5.081621891502814 -0.11907589603525259 ELIPQES(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELIPQESPR 9 0 Q96DF8 Q96DF8 DGCR14 Protein DGCR14 1 ELIPQES(1)PR 84.18799999999999 0.0134 8590300.0 25990.0 30299.0 34628.0 27477.0 29334.0 26103.0 26223.0 26665.0 25367.0 20428.0 True False 30389.593674101354 33306.8844808849 35453.6628474213 25937.552771635936 23586.21327588092 24734.112728294745 23738.96760192077 25965.072003902875 25737.94438535088 24131.434692040966 1.2593363826861257 1.3802281093494282 1.4691900129383784 1.0748450352266317 0.9774061748454653 1.0249748116489963 0.9837362719983805 1.0759854246240352 1.0665733187359876 1.0 14.558626070551213 -5.844672553273461 5.946092785292633 1.0245748161827548 1.3694428211808112 0.8840079895624214 0.05667983123960341 0.06237987700679428 3.4696092113666794 0.01641402766946358 0.024762477872403387 1.4299717135835283e-06 5.844672553273461 0.34486800499805637 ELIPQES(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 ELIPQESPR 9 0 Q96DF8 Q96DF8 DGCR14 Protein DGCR14 1 ELIPQES(1)PR 83.137 0.014756 10361000.0 30977.0 32769.0 48199.0 29188.0 46693.0 48983.0 38897.0 41321.0 43849.0 32081.0 True False 30535.26229951395 32693.12539382137 44236.26427352044 31334.58288831368 43946.60954197006 46888.111274949995 40910.89633551731 43240.924509726865 38910.26386955968 37626.15810475449 0.8115434537456928 0.8688935315373116 1.175678477466736 0.8327872008902817 1.1679802497937442 1.2461572915419488 1.0872993256876726 1.1492250787162586 1.0341280064052814 1.0 15.199448367169909 -4.631116415803308 0.8005962745378044 1.110415085077017 0.5402963956428709 0.40754935841359907 0.11349685375920893 3.022544909481093 1.2629021250500836 0.04281229603435747 1.6249454376486538 2.3382103803004557e-05 4.631116415803308 -0.570118689434146 ELIPTEEALR ddPTM_PC-9_AZD4547_30min_R2 1 ELIPTEEALR 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 101.9 0.015781 1939700.0 11015.0 9153.4 15295.0 17177.0 16116.0 14739.0 13116.0 14827.0 11598.0 13784.0 False True 14517.540873767019 12112.057545507072 15092.178306424532 13217.108032004533 13878.571582409268 13817.368000015002 14283.298590941227 12535.827840564758 12211.046602213717 13301.426355523068 1.091427376714302 0.9105833631502127 1.134628565616792 0.9936609562565052 1.0433897246400612 1.0387884449909166 1.0738170636121638 0.9424423746374827 0.9180253512544089 1.0 13.699293338486713 -7.7738795812001955 24.976956046000858 0.9476753518275545 1.037689904717153 0.3097846632259662 0.059466535498923445 262.23709679005395 526501.0251421108 0.030090782061042376 0.014615472472951068 1.6831406884244756e-08 7.7738795812001955 0.09001455288959859 ELIPTEEALR ddPTM_PC-9_Lapatinib_30min_R1 1 ELIPTEEALR 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 104.01 0.013347999999999999 0.0 20483.0 23162.0 27647.0 28729.0 24930.0 24996.0 27543.0 23158.0 23403.0 25579.0 False True 20190.90866387783 23108.369812069028 25373.970380506235 30841.82649713457 23463.6664142658 23926.979348521934 28969.04177106597 24234.005222435444 20767.10769548462 30000.296068124913 0.6730236467676237 0.7702713919754111 0.8457906656283264 1.028050737469347 0.7821144951697916 0.7975581072329538 0.965625196007494 0.807792202030429 0.692230091607313 1.0 14.872689118067536 -12.443923407036605 0.018693355664312915 1.9013014221383409 3.200088960785839e-06 0.15677224928015687 0.1076403451493981 6142.036948773287 12.67159059498096 779.798552781174 529.5261698427337 3.598127867967609e-13 12.443923407036605 -1.9012982220493801 ELISNASDALDK ddPTM_PC-9_Lapatinib_30min_R1 2 ELISNASDALDK 12 0 P08238;P14625;Q96GW1;A0A1W2PRR1;F8W026 P08238;P14625 HSP90AB1;HSP90B1 Heat shock protein HSP 90-beta;Endoplasmin 0 ; 276.17 1.9043999999999998e-63 28170900.0 126745.0 113639.0 126409.0 132617.0 129867.0 108310.0 143641.0 125454.0 109139.0 130830.0 False True 124937.59305781365 113375.87587745917 116016.13997285077 142370.09657734336 122228.47838834568 103677.83378294166 151078.0281391893 131283.0508323437 96846.61653537987 153443.79117998306 0.8142238411671355 0.7388756169643519 0.7560823353013271 0.9278322406043088 0.7965684205819502 0.6756730460428467 0.9845822172236424 0.8555774712210691 0.6311536999355216 1.0 17.22735074542812 -10.939071769320934 3.385062559363351 1.0020770129498793 0.802261706342725 0.26130897869679226 0.1017250090745679 75553747.59396051 92091648.47950159 1486864.3027359692 0.025336907296416578 1.1506102291752468e-11 10.939071769320934 -0.1998153066071543 ELISNSSDALDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELISNSSDALDK 12 0 P07900;P07900-2;G3V2J8;Q14568 P07900 HSP90AA1;HSP90AA2P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2 0 ; 164.11 0.0035149 20942200.0 90092.0 117443.0 86288.0 112876.0 92420.0 69655.0 96534.0 86173.0 82517.0 68729.0 False True 105342.79620189071 129101.96488625283 88345.4331690622 106551.92366892977 74310.96444252125 66002.16917938046 87389.60067436278 83911.05005784068 83723.6550181732 81189.02364153531 1.2975004683761047 1.590140626105594 1.0881450374267805 1.312393213882906 0.9152833857273369 0.8129444870625906 1.0763721098581525 1.033527024888532 1.0312188921969152 1.0 16.30899707483774 -5.7618817709448855 1.3809551933938298 0.9834085630179915 1.427379336115054 0.596773282640755 0.13593229013855682 0.2960562439147279 1.1294849127077566 0.04538039618140865 0.10931370764200325 1.7302873354822911e-06 5.7618817709448855 0.44397077309706245 ELISNSSDALDK ddPTM_PC-9_Lapatinib_30min_R1 3 ELISNSSDALDK 12 0 P07900;P07900-2;G3V2J8;Q14568 P07900 HSP90AA1;HSP90AA2P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2 0 ;; 263.07 3.8245999999999994e-50 81350700.0 282842.0 287857.0 300413.0 274467.0 314444.0 230584.0 312238.0 281959.0 275345.0 278477.0 False True 278808.62121312995 287190.48480238096 275714.20276771515 294652.2187750716 295949.02214069007 220722.4598375575 328404.1558477327 295059.84448193654 244332.74658860874 326611.3784027215 0.8536402576561515 0.8793033672215381 0.8441659446038998 0.9021492766604007 0.9061197548842778 0.6757953777268597 1.0054890232354388 0.9033973216882819 0.7480840005743439 1.0 18.317215526448592 -11.71565773390243 2.451188759412485 1.4130193510348452 0.8609074440190548 0.19676430734377648 0.08609377074008416 10064789.813651685 2390957.333161817 23109436.493685294 0.021283544758382723 1.9246079087447097e-12 11.71565773390243 -0.5521119070157904 ELISNSSDALDKIR ddPTM_PC-9_AZD4547_30min_R2 1 ELISNSSDALDKIR 14 1 P07900;P07900-2;G3V2J8 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 121.92 8.4521e-05 16190000.0 40540.0 32011.0 51660.0 107410.0 85993.0 63076.0 49799.0 63935.0 44554.0 47259.0 False True 53430.87671561641 42357.92974077685 50974.95464595566 82648.28396795764 74054.35629722741 59131.847748758104 54231.01452655394 54055.314830141535 46909.033481206265 45604.47679452008 1.1716147288863703 0.928810781705244 1.1177620757635993 1.8122844461157992 1.6238396206340409 1.2966237506722915 1.189159888203573 1.1853072029243612 1.0286058908769882 1.0 15.476887834032317 -7.891518550571228 1.4917092612323293 1.0121771977783556 1.3270880006086099 0.2030678013811038 0.2365528000113331 0.8066417296160012 3.2652543125353115 0.23365238678409417 0.08307957574586967 1.2837529347334527e-08 7.891518550571228 0.3149108028302543 ELISNSSDALDKIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELISNSSDALDKIR 14 1 P07900;P07900-2;G3V2J8 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 129.17 3.0346e-05 10603000.0 44404.0 24625.0 31763.0 48167.0 44179.0 55975.0 42866.0 50871.0 41389.0 38081.0 False True 51920.72018102333 27069.607259044536 32520.350381848304 45468.35914952094 35522.44209160511 53039.57246164415 38805.42215703527 49535.69015227989 41994.23582470484 44984.78385096988 1.1541840537242887 0.6017503018070167 0.7229188983009232 1.0107497526308695 0.7896546131973743 1.1790558478030924 0.8626344029037414 1.1011654588890927 0.9335208981736485 1.0 15.457149470435844 -6.371668455377835 1.6548550716206083 1.0056637425818387 0.8249821367868582 0.12806714006914877 0.1690036363203224 0.6590270844250617 3.5962165161555015 0.06089908223202005 0.0750259927164841 4.249438464066576e-07 6.371668455377835 -0.1806816057949805 ELISNSSDALDKIR ddPTM_PC-9_Lapatinib_30min_R1 2 ELISNSSDALDKIR 14 1 P07900;P07900-2;G3V2J8 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ; 98.58200000000001 0.0031341 26910000.0 158611.0 85527.0 95316.0 73939.0 76875.0 87642.0 60027.0 57258.0 104052.0 65033.0 False True 156349.17805430523 85328.96748626331 87479.48641040026 79376.72071327353 72353.36364206519 83893.75596348045 63134.904345633266 59918.41571060576 92332.56804386475 76273.86739897441 2.049839393044957 1.1187182503795612 1.1469129518870642 1.0406804246344121 0.9485996463716492 1.0999016940448005 0.8277396505330761 0.7855693929505853 1.2105400079019235 1.0 16.218901231737654 -2.6544064454654253 1.2135359426496912 0.980795089797417 199.99999999996916 0.8546417291890755 0.12766062812925763 96.46433555075994 1.0157352398491355 0.03763686279226045 52534.72776702936 0.0022161214357419444 2.6544064454654253 199.01920491017174 up ELKTDS(ph)SPNQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELKTDSSPNQAR 12 1 A6NLN1;P26599;P26599-2;P26599-3;K7ES59;A0A087WU68 A6NLN1 PTBP1 Polypyrimidine tract-binding protein 1 1 ELKT(0.12)DS(0.44)S(0.44)PNQAR 120.9 0.0022769 34974000.0 23600.0 8634.3 15322.0 28109.0 27823.0 32285.0 25653.0 34084.0 25504.0 24277.0 True False 27595.013878753045 9491.456241899225 15687.334589008582 26534.143860607583 22371.282879076665 30591.917765505714 23222.962128363426 33189.331114983135 25876.947751172353 28678.227923373757 0.9622286967132354 0.3309638331649968 0.547011992195754 0.9252365219882128 0.780078983222087 1.0667297103309592 0.80977674737831 1.1573006255359548 0.9023203184071822 1.0 14.80766825975571 -5.777751736171859 9.370688594843017 0.9477205728101009 0.5850190845191993 0.4230901452076611 0.17854531750339092 0.18235737296333007 93.92610695294672 0.04814381333892775 0.0737250696271394 1.6682005645341747e-06 5.777751736171859 -0.36270148829090165 ELKTDSS(ph)PNQAR ddPTM_PC-9_AZD4547_30min_R2 4 ELKTDSSPNQAR 12 1 A6NLN1;P26599;P26599-2;P26599-3;K7ES59;A0A087WU68 A6NLN1 PTBP1 Polypyrimidine tract-binding protein 1 1 ELKT(0.011)DS(0.046)S(0.943)PNQAR;ELKT(0.044)DS(0.184)S(0.772)PNQAR;ELKT(0.001)DS(0.003)S(0.996)PNQAR;ELKTDS(0.082)S(0.918)PNQAR 190.34 0.00038823 145658000.0 93629.0 57329.0 105277.0 243834.0 168200.0 106707.0 81006.0 99942.0 75567.0 117678.0 True False 123401.07439581788 75859.47812030227 103880.95819323011 187621.83849774662 144848.33334333834 100034.5944214398 88215.37707058442 84498.26033868763 79561.31734691182 113558.12903839539 1.0866775935881654 0.6680233177728144 0.9147822271544003 1.652209666419472 1.2755434997908723 0.8809109067622705 0.7768301381643733 0.7440969753043196 0.700621945964002 1.0 16.793071459245212 -6.935785845281434 6.192062468828906 0.7898401607394134 1.1117506481637363 0.27074173893742026 0.24696720123213103 0.31032972763084854 22.371614390346814 0.09847011619298805 0.08645541503364637 1.1593489011399897e-07 6.935785845281434 0.3219104874243228 ELKTDSS(ph)PNQAR ddPTM_PC-9_Lapatinib_30min_R1 2 ELKTDSSPNQAR 12 1 A6NLN1;P26599;P26599-2;P26599-3;K7ES59;A0A087WU68 A6NLN1 PTBP1 Polypyrimidine tract-binding protein 1 1 ELKT(0.003)DS(0.098)S(0.899)PNQAR;ELKT(0.001)DS(0.23)S(0.769)PNQAR 145.52 0.00030445 69776000.0 144853.0 44252.0 53599.0 47277.0 40378.0 42245.0 25712.0 28841.0 52827.0 23054.0 True False 142787.36965721313 44149.53721283475 49192.29711812322 50753.90829144871 38003.04542620238 40438.27982790483 27043.241550217783 30181.058149246935 46877.06696702843 27038.85318247595 5.280821959925228 1.6328184081952242 1.8193189180821123 1.8770732600575915 1.4054976803096217 1.4955619439552685 1.0001622985898189 1.116210733701068 1.7336928696890797 1.0 14.72274634244761 -4.759592069210864 5.266989083133517 1.4539033680659705 5.4984897355912965 0.9348207833264992 0.3035559398735056 0.03999118758034875 3.2130879698385666 0.08163518790383449 0.5955494745099604 1.7394339038439182e-05 4.759592069210864 4.044586367525326 ELLDT(ph)SFEDLSKPK ddPTM_PC-9_AZD4547_30min_R2 1 ELLDTSFEDLSKPK 14 1 P78345 P78345 RPP38 Ribonuclease P protein subunit p38 1 ELLDT(0.588)S(0.411)FEDLSKPK 69.729 0.020929 12367000.0 28743.0 28322.0 22635.0 23266.0 26803.0 28415.0 24118.0 35111.0 26974.0 26619.0 True False 37882.67610845982 37476.53263310369 22334.84511055374 17902.383156116754 23081.86610345715 26638.205558072204 26264.455277243098 29685.40172051457 28399.79057148757 25687.076912193035 1.4747756717494713 1.4589644731166156 0.8694973424536261 0.6969412369228717 0.8985789306567905 1.037027515786652 1.0224773868596935 1.1556551110112347 1.1056061640866142 1.0 14.64875510613617 -5.253516089943376 24.389914032052776 0.9702868284248567 1.4668701915492284 0.7209637855795443 0.12283205745521196 248.41960759702414 764692.5550340448 0.03661726210493591 0.09306601912214026 5.578069358683255e-06 5.253516089943376 0.4965833631243717 ELLDT(ph)SFEDLSKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELLDTSFEDLSKPK 14 1 P78345 P78345 RPP38 Ribonuclease P protein subunit p38 1 ELLDT(0.5)S(0.5)FEDLSKPK 72.797 0.015828000000000002 3566700.0 8520.1 9864.9 9092.7 11909.0 13643.0 10756.0 10998.0 9789.1 7361.1 8402.7 True False 9962.384650354397 10844.22207714715 9309.504452256782 11241.777339498929 10969.752087094965 10191.936425144166 9956.189821375312 9532.146497408792 7468.742161666982 9926.042994263404 1.003661243066547 1.0925020255719617 0.937886774985466 1.1325537624606232 1.1051485565229524 1.0267874550850153 1.0030371445226796 0.9603168657356957 0.7524390299320103 1.0 13.277002988287274 -7.827529586325912 2.4371556949573487 0.8736827267686257 1.049854474643569 0.42441961005016093 0.07760058426089056 0.2568950346112247 3.0060382583704057 0.05134026038928057 0.021009330165020015 1.4875460315050722e-08 7.827529586325912 0.17617174787494327 ELLDTS(ph)FEDLSKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELLDTSFEDLSKPK 14 1 P78345 P78345 RPP38 Ribonuclease P protein subunit p38 1 ELLDT(0.234)S(0.759)FEDLS(0.007)KPK 82.837 0.0041398 3196000.0 13176.0 18192.0 16493.0 16967.0 18366.0 13054.0 19876.0 13498.0 10132.0 10652.0 True False 15406.436562137718 19997.981533260452 16886.255670050814 16016.393997756182 14767.314141434148 12369.42525974637 17993.201390221464 13143.691802313173 10280.161332139203 12583.123278814392 1.224373013024263 1.5892700953609908 1.3419764946975765 1.2728472608006811 1.1735809793977918 0.9830170924711661 1.4299471595033775 1.0445492355973802 0.8169801013908387 1.0 13.619202440049412 -6.690573731657543 0.44250320139766564 0.9459121324099228 1.46447712886602 0.46020997972533695 0.16223315280389233 1.209070014681773 0.48881718732149715 0.16093693918726137 0.2594105689221866 2.0390424550192574e-07 6.690573731657543 0.5185649964560973 ELLHSVHPES(ph)PNLK ddPTM_PC-9_AZD4547_30min_R2 2 ELLHSVHPESPNLK 14 0 Q9Y217 Q9Y217 MTMR6 Myotubularin-related protein 6 1 ELLHSVHPES(1)PNLK;ELLHSVHPES(1)PNLK 99.73200000000001 0.0018402000000000002 12602000.0 39541.0 38632.0 80378.0 142548.0 109762.0 104493.0 63092.0 117147.0 72607.0 90820.0 True False 52114.215496107274 51119.03851006499 79312.13520194778 109685.76094464578 94523.44093003252 97959.03619143527 68707.06577460088 99044.62292025647 76444.85778987159 87640.41944345635 0.5946367649430319 0.5832815364724019 0.9049721088238082 1.2515430852702911 1.0785370669182721 1.1177381031892055 0.7839655059949724 1.1301249303599905 0.8722557271555746 1.0 16.41930876857346 -5.360187391879176 3.7435534434714124 1.0361652828966812 0.585507301821613 0.657989083582184 0.1259176006605571 0.132045420681957 3.3468142535958063 0.03384094926068037 0.07868758436445632 4.363275225093834e-06 5.360187391879176 -0.45065798107506816 ELLHSVHPES(ph)PNLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELLHSVHPESPNLK 14 0 Q9Y217 Q9Y217 MTMR6 Myotubularin-related protein 6 1 ELLHSVHPES(1)PNLK;ELLHSVHPES(1)PNLK 112.5 0.00025754 5727400.0 23091.2 21654.1 36901.0 43019.0 51997.0 55662.0 47014.0 49332.0 50921.0 38411.0 True False 27000.084088011114 23803.77594103865 37780.85978782183 40608.78489947975 41808.56111358766 52742.98673264916 42560.49356811589 48037.08727157461 51665.62329193249 45374.6102386913 0.5950482868277714 0.524605628914934 0.8326431806042442 0.8949671343920947 0.9214087105906899 1.1623898575700555 0.9379803670869709 1.0586776838165102 1.1386461067135911 1.0 15.469597630170295 -5.558699736458476 0.9865122181556859 1.0532609883781743 0.49273466651374714 0.8480409020031706 0.07805328922192172 0.26836744199992746 0.4378050228948237 0.0288761150892101 0.12340532759733627 2.762487130982249e-06 5.558699736458476 -0.5605263218644272 ELLHSVHPES(ph)PNLK ddPTM_PC-9_Lapatinib_30min_R1 2 ELLHSVHPESPNLK 14 0 Q9Y217 Q9Y217 MTMR6 Myotubularin-related protein 6 1 ELLHSVHPES(1)PNLK;ELLHSVHPES(1)PNLK 133.05 9.7965e-06 9020700.0 127496.0 102923.0 123299.0 100857.0 118311.0 122453.0 105925.0 105613.0 136329.0 96248.0 True False 125677.88366009685 102684.6881170702 113161.83216790385 108274.36022908913 111352.17958837544 117215.97064188508 111409.2782049945 110520.16553921186 120974.19241198669 112884.33855760163 1.1133332158027134 0.9096451237535768 1.0024582117754148 0.9591619316955987 0.9864271785723014 1.038372303364945 0.9869329937929835 0.9790566782903777 1.0716649799055786 1.0 16.78448581659211 -6.657948693313962 20.563600215095725 1.012178641403525 0.9880151744713759 0.028966345037022556 0.05384951020099922 12.031584699828134 2349.4919732200383 0.016871376323330866 0.016871318574488734 2.1981195389153442e-07 6.657948693313962 -0.024163466932149102 ELLIFNK ddPTM_PC-9_Lapatinib_30min_R1 1 ELLIFNK 7 0 P09874 P09874 PARP1 Poly [ADP-ribose] polymerase 1 0 124.37 0.021381 1955600.0 26374.0 19179.0 22745.0 22130.0 21554.0 22975.0 21104.0 15583.0 22115.0 22239.0 False True 25997.901923600748 19134.59220385424 20874.993898239016 23757.514023515887 20286.236096794437 21992.41280734083 22196.661857334926 16307.043068538364 19624.175818725915 26082.981518395172 0.9967381185032692 0.7336044842250669 0.8003300498264283 0.91084349412895 0.7777575612852178 0.8431709692325838 0.8510017093590548 0.6251985823414293 0.7523747162449911 1.0 14.67082117150909 ELLPVLISAMK ddPTM_PC-9_Lapatinib_30min_R1 1 ELLPVLISAMK 11 0 P18206;P18206-2;P18206-3 P18206 VCL Vinculin 0 162.36 0.0065274 1495800.0 6787.3 7695.6 10917.0 10244.0 10901.0 11185.0 9339.9 8205.6 10446.0 10969.0 False True 6690.511857361618 7677.781311016256 10019.446400838668 10997.377932982225 10259.8246121906 10706.64362350848 9823.474321518313 8586.862132015558 9269.461478743424 12864.977034726227 0.5200562612200571 0.5967971252721045 0.7788157237897383 0.8548307473303044 0.7975004218426833 0.8322318488877367 0.7635827327947781 0.6674603544831194 0.7205190847774166 1.0 13.651161261268177 -5.177416063750497 3.064432548563432 0.7927980220909736 0.5321642044601073 0.5786714825632158 0.083994606306313 0.19346609226743078 3.4444448191789636 0.022386381359725833 0.07581632394652167 6.646361149544834e-06 5.177416063750497 -0.26063381763086635 ELLS(ph)PGVK ddPTM_PC-9_AZD4547_30min_R2 2 ELLSPGVK 8 0 Q14694;Q14694-3;Q14694-2 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 ELLS(1)PGVK;ELLS(1)PGVK 101.38 0.0046034 12727500.0 76478.0 76234.0 93669.0 95217.0 85472.0 96547.0 86524.0 90665.0 77807.0 86392.0 True False 100796.41315877919 100875.14966287774 92426.88785776263 73266.1917379855 73605.68815411281 90509.90082756292 94224.46838080212 76654.80752443531 81919.71917386133 83367.44237567842 1.2090620785097455 1.210006529986903 1.108668866693303 0.878834586382371 0.8829068765528844 1.085674434147787 1.130231007402131 0.919481338758193 0.9826344294539682 1.0 16.34719645514103 -5.535507018263054 5.156030727510481 0.9854683163967453 1.2002278090027534 0.5937455798752024 0.07608360097742158 0.12949058633794078 10.144844937771143 0.02292134317211449 0.04308189489225095 2.9140230433469767e-06 5.535507018263054 0.21475949260600813 ELLS(ph)PGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELLSPGVK 8 0 Q14694;Q14694-3;Q14694-2 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 ELLS(1)PGVK;ELLS(1)PGVK 86.898 0.01213 9799600.0 70683.0 74822.0 63326.0 78967.0 79607.0 74914.0 84091.0 67602.0 72656.0 51041.0 True False 82648.23584711437 82249.83367862883 64835.93200519239 74542.7350044683 64008.57981363112 70985.37796144006 76125.29171388183 65827.51913023969 73718.45654835238 60294.32925966628 1.370746417812822 1.3641387952821895 1.0753238787343837 1.2363141927234846 1.0616019881068564 1.1773143317629626 1.2625613826142292 1.0917696562597772 1.2226432809439367 1.0 15.879734701182802 -5.247796542339443 24.092677752785633 1.1504338483433614 1.3674426899312793 0.553966831375543 0.0809388989387142 343.6078756620804 606792.5386297723 0.019224336264498664 0.05021508045832087 5.652016976855918e-06 5.247796542339443 0.2170088415879179 ELLS(ph)PGVK ddPTM_PC-9_Lapatinib_30min_R1 2 ELLSPGVK 8 0 Q14694;Q14694-3;Q14694-2 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 ELLS(1)PGVK;ELLS(1)PGVK 105.2 0.003846 9049000.0 59385.0 65211.0 67390.0 65429.0 74661.0 67250.0 66046.0 69606.0 65008.0 56977.0 True False 58538.159010124764 65060.00793605188 61849.454332922694 70240.86692474558 70269.58676917372 64373.87426740684 69465.53871444002 72840.1488691961 57686.11447541192 66825.39853291969 0.8759866801435917 0.9735820416245159 0.9255381290760918 1.051110333298549 1.0515401076816226 0.9633144834249635 1.0395080349609847 1.0900069504757748 0.8632363703299795 1.0 16.02810891597968 -4.616782586036579 1.0116312862659094 1.0101782642453008 0.7840368301996726 0.256879926075275 0.06325384059767365 3.3390508152902103 2.214648803492139 0.02008172596319631 0.8876468876159266 2.4166703510455924e-05 4.616782586036579 -0.22614143404562814 ELLS(ph)PLSEPDDRYPLIVK ddPTM_PC-9_AZD4547_30min_R2 1 ELLSPLSEPDDRYPLIVK 18 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 ELLS(0.894)PLS(0.106)EPDDRYPLIVK 100.92 0.00026318 8723600.0 23762.0 26871.0 33613.0 34038.0 31510.0 40165.0 32423.0 39045.0 28105.0 32956.0 True False 31317.821719696007 35556.525258955204 33167.26965765597 26191.06498185773 27135.380402191335 37653.47620059722 35308.584188326255 33011.49241484124 29590.572922505322 31802.220471025707 0.9847683984276814 1.1180516559008815 1.0429230778987248 0.8235608895837894 0.8532542696794954 1.1839889052685004 1.1102553112759883 1.0380247644945821 0.9304561909274427 1.0 14.956839879357814 -6.7578541539671635 24.998653357157604 1.0585284629100942 0.9695672761402094 0.15858319280948074 0.10058372905122517 203.4735456011235 1418758.8871079525 0.03765186123515833 0.036261970366079116 1.746408538436002e-07 6.7578541539671635 -0.08896118676988474 ELLS(ph)PLSEPDDRYPLIVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELLSPLSEPDDRYPLIVK 18 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 ELLS(0.542)PLS(0.454)EPDDRY(0.004)PLIVK 68.168 0.0057815 9719100.0 4653.8 7192.7 6007.7 6797.8 5796.0 6134.4 6130.3 4716.5 4982.8 4642.1 True False 5441.596423260212 7906.743721101716 6150.946352329125 6416.941304764959 4660.315406934135 5812.701265005983 5549.5936044714545 4592.696872544832 5055.664023468538 5483.675983156617 0.9923263956467059 1.4418692397923714 1.1216830409422551 1.1701897275613864 0.8498524386284904 1.0600008612580292 1.0120206995302616 0.8375215615677383 0.9219479850737464 1.0 12.420927613017867 -6.161265152208608 5.698084161245879 0.9481485450476904 1.2001291338840505 0.46643711033300683 0.1225031103031076 0.19687307930742437 9.198697461826875 0.03546526549765044 0.04611511038732804 6.898185165391856e-07 6.161265152208608 0.2519805888363601 ELLS(ph)PLSEPDDRYPLIVK ddPTM_PC-9_Lapatinib_30min_R1 2 ELLSPLSEPDDRYPLIVK 18 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 ELLS(0.5)PLS(0.5)EPDDRYPLIVK;ELLS(0.539)PLS(0.451)EPDDRY(0.01)PLIVK 83.77600000000001 0.0009753 22448900.0 31263.0 27843.0 28798.0 27149.0 32813.0 30443.0 31385.0 30954.0 30581.0 26858.0 True False 30817.183887067946 27778.531244168826 26430.3396034947 29145.628026409064 30883.003852840102 29141.02385609912 33009.96173201558 32392.235843132672 27136.64574779366 31500.369513964568 0.9783118218154947 0.8818477901300238 0.8390485575662137 0.9252471788779616 0.9804013200273483 0.9251010164557112 1.0479230003121642 1.0283128846718044 0.861470711820177 1.0 14.943081131744146 -6.122883065045068 3.9725296633103837 0.9764580110419553 0.8959160775556132 0.2458060496166924 0.05881619394499822 0.32051722418202194 8.718328016217368 0.01796302703783539 0.023909157539655772 7.5355843405178e-07 6.122883065045068 -0.08054193348634209 ELLSPLS(ph)EPDDRYPLIVK ddPTM_PC-9_AZD4547_30min_R2 2 ELLSPLSEPDDRYPLIVK 18 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 ELLS(0.035)PLS(0.965)EPDDRY(0.001)PLIVK;ELLS(0.41)PLS(0.584)EPDDRY(0.006)PLIVK 64.2 0.007631499999999999 20562700.0 38597.0 43886.0 56195.0 59191.0 60045.0 58160.0 49810.0 64688.0 46109.0 56452.0 True False 50870.04313252701 58071.29126249515 55449.817582839285 45545.429441833876 51708.7882021447 54523.246005894 54242.99350524413 54691.9559823601 48546.22760661086 54475.63266265151 0.9338128011756623 1.0660048984122918 1.0178829482572613 0.8360697657956678 0.9492095029416013 1.0008740301106247 0.9957294822283564 1.0039710106911142 0.8911549115407366 1.0 15.733323425988745 ELLSPLS(ph)EPDDRYPLIVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ELLSPLSEPDDRYPLIVK 18 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 ELLS(0.115)PLS(0.884)EPDDRY(0.001)PLIVK;ELLS(0.032)PLS(0.967)EPDDRYPLIVK;ELLS(0.033)PLS(0.959)EPDDRY(0.008)PLIVK 82.859 0.0011710000000000002 28316500.0 36795.0 39962.0 40082.0 45610.0 45771.0 37862.0 44477.0 39334.0 38503.0 31288.4 True False 43023.66676562367 43929.16326034269 41037.706891831476 43054.61956961512 36802.50111987269 35876.45006775831 40263.81657440529 38301.52417781794 39066.033534480426 36960.73924116186 1.164036965951962 1.188535839981803 1.1103053600759492 1.1648744168424727 0.99571875117928 0.970663758472774 1.0893671880232556 1.0362759231601866 1.056960286415862 1.0 15.17370599152238 -6.255306398002063 24.941968053299203 1.0271632286260635 1.1558642176405296 0.7622869166977755 0.036124852001790275 253.02172766777892 1029003.4033944003 0.011285322160695081 0.014194743780814386 5.55512200978725e-07 6.255306398002063 0.12870098901446614 ELLSPLS(ph)EPDDRYPLIVK ddPTM_PC-9_Lapatinib_30min_R1 2 ELLSPLSEPDDRYPLIVK 18 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 ELLS(0.027)PLS(0.836)EPDDRY(0.137)PLIVK;ELLS(0.434)PLS(0.566)EPDDRYPLIVK 97.713 0.00035658 14430200.0 63515.0 55815.0 55019.0 58143.0 58257.0 55359.0 53530.0 54564.0 57838.0 45654.0 True False 62609.26445277552 55685.763796763385 50495.55019948175 62419.030179362104 54830.43779766877 52991.424618131925 56301.521475698406 57099.24263567526 51323.675378859094 53545.233069868875 1.1692780265066618 1.0399761212002088 0.9430447362810482 1.1657252494897947 1.0240022249249132 0.9896571847765737 1.0514758877271664 1.0663739676166675 0.958510635519861 1.0 15.708470522544063 -4.767107222966983 5.566335800851699 1.029420643320764 1.1752856827112912 0.34147225659505054 0.0595063925778576 0.1655271155063676 16.667067191082545 0.014474482836649396 0.09236502587200156 1.7095931815123334e-05 4.767107222966983 0.1458650393905272 ELLTLDEKDPR ddPTM_PC-9_Lapatinib_30min_R1 1 ELLTLDEKDPR 11 1 P46781;B5MCT8;C9JM19;F2Z3C0;A8MXK4 P46781 RPS9 40S ribosomal protein S9 0 77.744 0.024839 14813000.0 114560.0 120770.0 125200.0 112620.0 144590.0 117210.0 140330.0 112210.0 119690.0 127090.0 False True 112926.3533922692 120490.36448508641 114906.53928597606 120902.45048930652 136085.50047487748 112197.20152985511 147595.6007600364 117423.68624274449 106209.25180842447 149057.33716321993 0.7576034534188224 0.8083491009446099 0.7708881794939872 0.81111371496538 0.9129741820482269 0.7527116991698138 0.9901934622541734 0.7877752848500431 0.7125395759091269 1.0 17.185507866394296 -6.007610320285629 20.862462911756474 0.8510614127361491 0.7834059604714213 0.139098774579828 0.0892660881246473 93.54145212175463 256445.4574613276 0.024945805623676102 0.03511799072416957 9.826292320036355e-07 6.007610320285629 -0.0676554522647278 ELLTSDS(ph)PPHNDIMTPVDPGVAQPNSR ddPTM_PC-9_AZD4547_30min_R2 1 ELLTSDSPPHNDIMTPVDPGVAQPNSR 27 0 Q12778 Q12778 FOXO1 Forkhead box protein O1 1 ELLT(0.054)S(0.198)DS(0.748)PPHNDIMT(0.001)PVDPGVAQPNSR 73.435 5.7785e-05 12750000.0 27165.0 20809.0 33638.0 42289.0 40574.0 34229.0 28750.0 38193.0 26688.0 35572.0 True False 35802.90493289883 27535.10230782623 33191.93814132123 32539.924408536983 34941.00045822 32088.65521897776 31308.6943038701 32291.149437828975 28098.673195368137 34326.63510727413 1.043006540577345 0.8021497656783518 0.9669441248055086 0.9479497278671941 1.0178976281545196 0.9348034002953549 0.9120816592138242 0.9407024410320423 0.8185676547543038 1.0 15.06704082257213 -9.830990348863788 6.575680157494881 0.9999999983156524 0.931612869961838 0.07580794149385262 0.07168192513783657 19818531.157702215 7407438.684721801 0.06642781850815038 0.01660695466549485 1.4757393276207608e-10 9.830990348863788 -0.06838712835381444 ELLTSDS(ph)PPHNDIMTPVDPGVAQPNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELLTSDSPPHNDIMTPVDPGVAQPNSR 27 0 Q12778 Q12778 FOXO1 Forkhead box protein O1 1 ELLT(0.082)S(0.233)DS(0.681)PPHNDIMT(0.004)PVDPGVAQPNSR;ELLT(0.188)S(0.221)DS(0.58)PPHNDIMT(0.01)PVDPGVAQPNS(0.001)R 58.318999999999996 0.0019493 14713200.0 26743.1 30752.8 37330.4 38136.8 39604.8 37464.9 35125.0 29851.7 31319.0 25980.0 True False 31270.17862969832 33805.73474582518 38220.49831233038 36000.11873717381 31844.523745435643 35500.174690812935 31797.70571702199 29068.124505490636 31776.981125273174 30689.96834243317 1.0189055355414924 1.101523936702275 1.2453743153421635 1.1730256067875644 1.037619960702473 1.1567354613959957 1.0360944450065535 0.947153942329093 1.035419156211284 1.0 14.905479537174042 -7.433629654803614 4.4080850257298 0.9927289696643223 1.124871776691531 0.4529693978825985 0.06431422580830787 0.21400862779243532 7.276653203296135 0.030127956281013325 0.019416380512049424 3.6844303000080696e-08 7.433629654803614 0.1321428070272087 ELLTSDSPPHNDIMT(ph)PVDPGVAQPNSR ddPTM_PC-9_AZD4547_30min_R2 1 ELLTSDSPPHNDIMTPVDPGVAQPNSR 27 0 Q12778 Q12778 FOXO1 Forkhead box protein O1 1 ELLT(0.028)S(0.047)DS(0.326)PPHNDIMT(0.599)PVDPGVAQPNS(0.001)R 50.992 0.016097 7974600.0 5715.6 3038.2 9863.3 13550.0 10340.0 7093.8 9310.5 8957.2 5963.7 8261.1 True False 7533.041908134605 4020.23873476081 9732.506197434264 10426.256845413132 8904.469481391898 6650.223564590975 10139.11646317157 7573.070555979412 6278.929006865147 7971.881403483145 0.9449515775339059 0.5043023762250467 1.2208543635862235 1.3078790711635022 1.1169846904021024 0.8342100475410109 1.2718599223944171 0.9499728072560788 0.7876345230276133 1.0 12.960704532235015 -5.268506258547487 24.948811245382203 1.069610457667189 0.7246269718153958 0.32572584670640603 0.19338156993568154 547.6287304388975 1933346.3405021788 0.051308505722720915 0.11058240242334763 5.38882079574902e-06 5.268506258547487 -0.34498348585179317 ELLTSDSPPHNDIMT(ph)PVDPGVAQPNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELLTSDSPPHNDIMTPVDPGVAQPNSR 27 0 Q12778 Q12778 FOXO1 Forkhead box protein O1 1 ELLT(0.01)S(0.025)DS(0.209)PPHNDIMT(0.755)PVDPGVAQPNSR 70.593 0.00019275 8362900.0 21411.0 19429.0 28695.0 25453.0 29329.0 28131.0 26976.0 23506.0 22276.0 19943.0 True False 25035.4594134738 21357.782718212246 29379.197626393518 24026.95092973939 23582.19298998813 26655.76083820479 24420.637990672887 22888.99240666569 22601.744357948362 23558.508031298858 1.0626929082356458 0.906584690755339 1.2470737784991108 1.0198842345117176 1.0010053675155406 1.131470668804283 1.0365952698799363 0.9715807289772478 0.959387764620774 1.0 14.523960555220253 -7.676132489777888 4.435760117666946 0.973933492526865 1.0599532916988246 0.16844726525113618 0.08351252442582535 0.38398311890375986 13.681565828333182 0.04185236884799285 0.022741975517442583 2.1079849709904536e-08 7.676132489777888 0.08601979917195957 ELMETMHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELMETMHR 8 0 E9PM90;Q9UK41;Q9UK41-2 E9PM90 VPS28 Vacuolar protein sorting-associated protein 28 homolog 0 ; 71.37899999999999 0.012342 0.0 5913.6 8230.0 10875.3 9199.6 13622.4 10418.7 7368.5 9879.3 8448.900000000001 7980.200000000001 False True 6914.655681076014 9047.020009824837 11134.60839680492 8684.176237505615 10953.18850921662 9872.325030926877 6670.502336679759 9619.9788429836 8572.449178751569 9426.947088771554 0.7334989383054952 0.9596977605401807 1.1811468009688273 0.9212076991340437 1.1619019822719672 1.0472451938004206 0.7075994246986917 1.0204765925165706 0.9093558177453039 1.0 13.202574915265856 ELNDWLT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 2 ELNDWLTK 8 0 A0A075B6G3;P11532-11;A0A087WTU7;A0A5H1ZRP8;A0A087WV90;P11532;P11532-4;Q4G0X0 A0A075B6G3 DMD Dystrophin 1 ELNDWLT(1)K;ELNDWLT(1)K 101.33 0.011295999999999999 15128800.0 105638.0 82463.0 105908.0 66385.0 59367.0 69850.0 79873.0 90031.0 112762.0 60496.0 True False 104131.58274836335 82272.06199001143 97200.6530567025 71267.17435386826 55875.14978001274 66862.67832830279 84008.43311840955 94214.1689343244 100061.55612349861 70952.6529941469 1.4676207069657208 1.1595346828933697 1.3699368375234802 1.0044328343824904 0.7874990916072165 0.9423562827709697 1.1840069338258523 1.3278456119476802 1.410258135545023 1.0 16.114569008725226 -4.361230258262417 1.1112330109052788 1.1109509721094246 1.9621760468960154 0.227508265276555 0.18967519857993254 6.632374068452734 3.619746216892091 0.06592114871078268 8.281975453559555 4.352810311756401e-05 4.361230258262417 0.8512250747865908 ELNFVTDSVEQELPS(ph)SPKQPICFDR ddPTM_PC-9_AZD4547_30min_R2 2 ELNFVTDSVEQELPSSPKQPICFDR 25 1 B4DP81;Q8TAP6-2;Q8TAP6 B4DP81 CEP76 Centrosomal protein of 76 kDa 1 ELNFVTDSVEQELPS(0.5)S(0.5)PKQPICFDR;ELNFVTDSVEQELPS(0.5)S(0.5)PKQPICFDR 104.97 3.2888000000000007e-07 20145100.0 40950.0 39361.0 51722.0 68707.0 60911.0 58607.0 43896.0 50780.0 50039.0 64039.0 True False 53971.24818708663 52083.67350369301 51036.13248544555 52867.662662568284 52454.55905039278 54942.29502523094 47802.65896218025 42933.11780831446 52683.959383356814 61797.01410195461 0.8733633650655549 0.8428186096137876 0.8258672886888122 0.85550513128912 0.8488202838384981 0.8890768562795842 0.7735431825769762 0.6947442110630472 0.8525324426911177 1.0 15.915249511459498 -7.2644737274600955 24.943351357693185 0.804766978461261 0.8536075412106949 0.0 0.07485867701314006 681.8775709783085 5605205.096398271 0.02907123416962333 0.02053964142482651 5.4390903437098944e-08 7.2644737274600955 0.048840562749433936 ELNFVTDSVEQELPS(ph)SPKQPICFDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELNFVTDSVEQELPSSPKQPICFDR 25 1 B4DP81;Q8TAP6-2;Q8TAP6 B4DP81 CEP76 Centrosomal protein of 76 kDa 1 ELNFVTDSVEQELPS(0.5)S(0.5)PKQPICFDR;ELNFVTDSVEQELPS(0.5)S(0.5)PKQPICFDR 93.404 1.5866e-06 15363300.0 52137.0 40443.0 52383.0 63642.0 65223.0 65306.0 73337.0 70405.0 51721.0 56769.0 True False 60962.76434731134 44457.91376152443 53632.009383633784 60076.345070147894 52443.02135722307 61881.23839535748 66389.9884460995 68556.94335026378 52477.321778481244 67060.77031684318 0.9090674631275412 0.6629496433082018 0.7997523608845784 0.8958493137836645 0.7820223524043136 0.9227636083359336 0.989997402839627 1.0223107045497928 0.7825338350654301 1.0 16.03318143479428 -6.84831031189337 4.872430838393894 0.9510485854925899 0.8060536560447457 0.3668037163588198 0.0879708523107568 0.22622439771409084 9.30152288702671 0.031166452801827015 0.027636716539112365 1.4180439395169256e-07 6.84831031189337 -0.1449949294478442 ELNFVTDSVEQELPS(ph)SPKQPICFDR ddPTM_PC-9_Lapatinib_30min_R1 2 ELNFVTDSVEQELPSSPKQPICFDR 25 1 B4DP81;Q8TAP6-2;Q8TAP6 B4DP81 CEP76 Centrosomal protein of 76 kDa 1 ELNFVTDSVEQELPS(0.5)S(0.5)PKQPICFDR;ELNFVTDSVEQELPS(0.5)S(0.5)PKQPICFDR 128.51 7.5775e-08 12945700.0 67741.0 56008.0 61405.0 52008.0 62276.0 67084.0 67783.0 57741.0 68712.0 56823.0 True False 66775.000917822 55878.31691712128 56356.51793015462 55832.84181360208 58613.04811932677 64214.973700441915 71292.47207523386 60423.85765388396 60972.93099056273 66644.77983811194 1.0019539576847039 0.838450018934061 0.8456253898212476 0.8377676683639238 0.8794844586733546 0.9635409383364713 1.069738278803107 0.9066555220177885 0.9148943268876153 1.0 16.024204255664756 -6.765716825734165 5.555244023361875 0.9719395054756212 0.8734885011905449 0.3492356970409698 0.061375966442110776 0.1908163255998978 18.837889126273772 0.021885969792056054 0.02040133352221307 1.7150752283857748e-07 6.765716825734165 -0.09845100428507636 ELNSNHDGADET(ph)SEKEQQEAIEHIDEVQNEIDR ddPTM_PC-9_AZD4547_30min_R2 1 ELNSNHDGADETSEKEQQEAIEHIDEVQNEIDR 33 1 Q01105-2 Q01105-2 SET Protein SET 1 ELNS(0.098)NHDGADET(0.451)S(0.451)EKEQQEAIEHIDEVQNEIDR 43.795 0.012882 2843900.0 678.6 1164.2 2661.6 2455.5 903.4 2269.1 2587.3 3056.6 947.55 1256.2 True False 894.3806842431494 1540.504882828166 2626.305444941454 1889.4224120968217 777.9785038190946 2127.212818293915 2817.5646877357603 2584.2727036804667 997.6355585383347 1212.2208203575224 0.7378034341790699 1.2708120970681087 2.1665239540819576 1.5586454054959815 0.6417795262662161 1.754806370729165 2.324299863868673 2.131849791953155 0.8229817057952366 1.0 10.243436811374544 ELNSNHDGADET(ph)SEKEQQEAIEHIDEVQNEIDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ELNSNHDGADETSEKEQQEAIEHIDEVQNEIDR 33 1 Q01105-2 Q01105-2 SET Protein SET 1 ELNSNHDGADET(0.5)S(0.5)EKEQQEAIEHIDEVQNEIDR;ELNS(0.002)NHDGADET(0.499)S(0.499)EKEQQEAIEHIDEVQNEIDR;ELNS(0.034)NHDGADET(0.483)S(0.483)EKEQQEAIEHIDEVQNEIDR 76.835 2.7442000000000002e-08 14113300.0 26882.9 35948.4 43181.8 39816.5 52845.4 40499.9 43333.2 35672.9 36539.5 33151.7 True False 31433.64400852247 39517.11957730099 44211.41787988844 37585.71059183469 42490.72322387802 38376.013948000786 39228.365590800175 34736.52417356184 37073.821061557486 39161.840781287174 0.8026600226499697 1.0090720657897057 1.1289412601108915 0.9597534191956164 1.0850032168094994 0.9799338637405961 1.001698715080441 0.8869992697115531 0.9466822887261364 1.0 15.25716095919021 -7.701879568260011 15.764967869827801 0.9376357789367883 1.002465009126786 0.06403599138597038 0.08464170708623317 5.8694144538357005 1551.2346245564709 0.0398752114585599 0.023019368398031294 1.9866457464463142e-08 7.701879568260011 0.06482923018999764 ELNSNHDGADET(ph)SEKEQQEAIEHIDEVQNEIDR ddPTM_PC-9_Lapatinib_30min_R1 5 ELNSNHDGADETSEKEQQEAIEHIDEVQNEIDR 33 1 Q01105-2 Q01105-2 SET Protein SET 1 ELNS(0.002)NHDGADET(0.499)S(0.499)EKEQQEAIEHIDEVQNEIDR;ELNS(0.068)NHDGADET(0.466)S(0.466)EKEQQEAIEHIDEVQNEIDR;ELNSNHDGADET(0.5)S(0.5)EKEQQEAIEHIDEVQNEIDR;ELNS(0.02)NHDGADET(0.49)S(0.49)EKEQQEAIEHIDEVQNEIDR;ELNS(0.015)NHDGADET(0.492)S(0.492)EKEQQEAIEHIDEVQNEIDR 66.378 1.4380999999999998e-05 16219860.0 30276.129999999997 28872.0 46227.600000000006 36361.990000000005 44289.67 41251.899999999994 39003.399999999994 49424.9 49627.899999999994 39146.270000000004 True False 29844.38683423774 28805.148657890375 42426.94517169636 39036.172044642786 41684.63868744146 39487.652399875675 41022.80520689809 51721.36128846829 44038.28329704486 45912.650610374025 0.6500253511282653 0.6273902350430147 0.9240796296371949 0.8502269314815493 0.9079118311244431 0.8600603945735468 0.8934967740161125 1.1265165613588377 0.9591753625980886 1.0 15.486604103084293 -3.9458194738807246 0.3598465682245262 1.0154147165822032 4.0767451887916983e-13 0.712177668865838 0.07631141727001675 6.38256202878397 0.4139325552838343 0.06958659884067989 3.157971461670523 0.00011328711735852152 3.9458194738807246 -1.0154147165817955 ELNSNHDGADETS(ph)EKEQQEAIEHIDEVQNEIDR ddPTM_PC-9_Lapatinib_30min_R1 1 ELNSNHDGADETSEKEQQEAIEHIDEVQNEIDR 33 1 Q01105-2 Q01105-2 SET Protein SET 1 ELNS(0.006)NHDGADET(0.242)S(0.753)EKEQQEAIEHIDEVQNEIDR 44.452 0.0054055 5931800.0 4950.5 5217.9 8628.2 6091.8 7350.9 7776.2 5707.0 6017.7 7898.3 6675.9 True False 4879.904962189484 5205.818273136818 7918.822701815167 6539.8112936490725 6918.534514425451 7443.630053207563 6002.48053543454 6297.304310693917 7008.7102812137855 7829.8204199224065 0.6232460900090278 0.6648707114522057 1.0113670910850396 0.8352440979372912 0.8836134347119564 0.9506769828676772 0.7666179060967563 0.8042718699742955 0.8951303995913666 1.0 12.934763503767368 -5.143516798130323 6.504985509029935 0.8811053314388251 0.6348657716472879 0.6314301935150559 0.07591690597190251 0.14823462823229094 7.276481257899245 0.019227031128581606 0.052337072231193056 7.185933632807737e-06 5.143516798130323 -0.24623955979153722 ELNTLADQVDTT(ph)HELLT(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELNTLADQVDTTHELLTK 18 0 A0A0G2JME4;Q9BWW9 A0A0G2JME4 APOL5 Apolipoprotein L5 2 ELNTLADQVDT(0.196)T(0.86)HELLT(0.944)K 70.41 0.026792000000000003 0.0 11698.0 21364.0 23788.0 35944.0 24594.0 39489.0 30553.0 24424.0 39358.0 31260.0 True False 13678.24035396836 23484.876730242748 24355.19613649237 33930.17421202029 19774.982249506233 37418.127323588524 27658.7986554355 23782.895879367086 39933.53629197937 36927.19054597616 0.3704110751923648 0.6359778900862476 0.6595464148882098 0.9188398497247052 0.5355127741138447 1.013294723220309 0.7490090160257099 0.6440483429075444 1.0814127937044158 1.0 15.172395884725825 -4.504942953825544 0.6296766604533446 0.8513818009157201 2.6045307067487076e-49 0.45784233418418696 0.16323924828485215 4.6669482975598084 1.0947934013122456 0.07378854391836172 3.0990136235949564 3.126490016093934e-05 4.504942953825544 -0.8513818009157201 ELNVS(ph)FINEK ddPTM_PC-9_AZD4547_30min_R2 1 ELNVSFINEK 10 0 P49585;C9JEJ2;C9J050;Q9Y5K3-2;Q9Y5K3-4;Q9Y5K3-3;Q9Y5K3 P49585 PCYT1A;PCYT1B Choline-phosphate cytidylyltransferase A;Choline-phosphate cytidylyltransferase B 1 ELNVS(1)FINEK 117.93 0.00091551 9679400.0 31118.0 34237.0 50882.0 49181.0 37649.0 45448.0 54472.0 54079.0 46717.0 43317.0 True False 41012.87670539099 45303.44070897431 50207.27143429181 37843.080288875535 32422.086219044824 42606.12937544483 59319.90247375345 45722.33316179278 49186.365245354216 41800.48501466867 0.9811579145791899 1.0838017954355403 1.2011169587308141 0.9053263443138423 0.7756389957596719 1.0192735648998674 1.4191199564535397 1.0938230297028335 1.176693649083107 1.0 15.35123206166895 -7.031174182514265 24.857731796115985 1.1857947787744216 0.9913141559855302 0.27152695723942966 0.14285866399143743 850.7018842862751 678331.9146501945 0.05693769039562209 0.04415593363640086 9.307345108532879e-08 7.031174182514265 -0.19448062278889144 ELNVS(ph)FINEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELNVSFINEK 10 0 P49585;C9JEJ2;C9J050;Q9Y5K3-2;Q9Y5K3-4;Q9Y5K3-3;Q9Y5K3 P49585 PCYT1A;PCYT1B Choline-phosphate cytidylyltransferase A;Choline-phosphate cytidylyltransferase B 1 ELNVS(1)FINEK;ELNVS(1)FINEK 89.62899999999999 0.009226799999999999 9423700.0 26961.0 34200.0 29725.0 34012.0 34268.0 27237.0 35135.0 30766.0 26318.8 22231.0 True False 31524.96479597717 37595.14998007406 30433.75673269025 32106.41790839178 27553.43139489629 25808.64377200182 31806.758444628267 29958.42509927154 26703.66265972219 26261.304319500818 1.200434084021018 1.4315796931745344 1.1588821469956883 1.2225751439371793 1.0492026998992576 0.9827632115300965 1.2111644592233588 1.1407820698770608 1.01684449236944 1.0 14.68065095185583 -5.802326111727554 1.6279564619436329 1.0794448746047216 1.3069566099404406 0.49524766571451706 0.09225738521100092 0.32098990897962376 1.731290491062161 0.0295759834827176 0.061504481772895206 1.5764270860503553e-06 5.802326111727554 0.227511735335719 ELNVS(ph)FINEK ddPTM_PC-9_Lapatinib_30min_R1 2 ELNVSFINEK 10 0 P49585;C9JEJ2;C9J050;Q9Y5K3-2;Q9Y5K3-4;Q9Y5K3-3;Q9Y5K3 P49585 PCYT1A;PCYT1B Choline-phosphate cytidylyltransferase A;Choline-phosphate cytidylyltransferase B 1 ELNVS(1)FINEK;ELNVS(1)FINEK 124.51 0.00041018 15964200.0 70804.0 88490.0 83563.0 79798.0 80807.0 81170.0 73556.0 70885.0 65333.0 58429.0 True False 69794.32197613674 88285.1068418092 76692.7727025082 85666.61111832458 76054.0911326745 77698.54831651167 77364.36976772787 74178.57587841501 57974.50955301018 68528.37479825136 1.0184733284805358 1.2883000231907145 1.1191389395749274 1.2500896361620784 1.1098189816492652 1.1338157156835758 1.1289392167184735 1.082450533764998 0.8459927690345507 1.0 16.06441385236063 -8.059762518783195 3.7197113444039265 0.9249826379424155 1.1541990551016144 0.5593971249871625 0.07905633925012866 0.15955707838961936 4.26647131225698 0.054694811664676025 0.019519661627033728 8.71439981122854e-09 8.059762518783195 0.22921641715919883 ELNYFAK ddPTM_PC-9_Lapatinib_30min_R1 2 ELNYFAK 7 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 ; 124.83 0.02129 34923000.0 213390.0 188782.0 189174.0 180473.0 208320.0 175546.0 181811.0 170563.0 168263.0 160963.0 False True 210347.01946906638 188344.88687773194 173620.84395275704 193745.586460279 196067.0271728782 168038.30679771304 191224.28397194456 178487.9796508445 149311.44905205883 188785.2400802843 1.1142132688954525 0.9976674383952628 0.9196738255539557 1.0262750752012457 1.0385718030154116 0.8901029907118361 1.0129196747088014 0.9454551615101864 0.7909063705857591 1.0 17.52638644837714 -6.9769330590257805 0.7463858878195208 0.9104893867815191 1.020656555070981 0.2345229887960968 0.07507936828948011 1.0848256243960117 1.271920681566316 0.058059595367792156 0.04635427293575423 1.0545494292552586e-07 6.9769330590257805 0.11016716828946183 ELPDSS(ph)SPVPANNIR ddPTM_PC-9_AZD4547_30min_R2 2 ELPDSSSPVPANNIR 15 0 A0A0C4DH56;Q9BWT3-2;Q9BWT3 A0A0C4DH56 PAPOLG Poly(A) polymerase gamma 1 ELPDS(0.005)S(0.497)S(0.497)PVPANNIR;ELPDS(0.015)S(0.492)S(0.492)PVPANNIR 109.99 0.00057307 10990800.0 52913.0 47042.0 72090.0 81648.0 83235.0 70034.0 59716.0 92010.0 59057.0 71443.0 True False 69738.2333412286 62247.40654355146 71134.03949723084 62825.315049025245 71679.25699068217 65654.76290881661 65030.608314779354 77791.96867946058 62178.63245274495 68941.80231555674 1.0115522222936162 0.9028978711440695 1.031798373527282 0.911280426952933 1.0397067466063 0.9523215335784977 0.9432681788202276 1.1283715549442026 0.9019003037974584 1.0 16.073091394496693 ELPDSSS(ph)PVPANNIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELPDSSSPVPANNIR 15 0 A0A0C4DH56;Q9BWT3-2;Q9BWT3 A0A0C4DH56 PAPOLG Poly(A) polymerase gamma 1 ELPDS(0.002)S(0.167)S(0.832)PVPANNIR 130.66 1.1706e-05 4783400.0 16608.0 19708.0 22433.0 23371.0 22820.0 20001.0 16284.0 9954.2 15321.0 15261.0 True False 19419.406377047915 21664.479994365473 22967.88779762627 22061.598639804302 18348.58481474068 18952.112350251802 14741.461634049425 9692.912797346708 15545.040640515657 18027.698493990472 1.077198311449538 1.2017329889107764 1.274033277474804 1.2237612386938095 1.0177996276594694 1.0512774193871437 0.8177117916057608 0.5376677894062759 0.8622864779826217 1.0 14.137927606422583 -6.999662558390344 1.6108471278204883 0.761507266518355 1.1872324316662093 0.633630685291297 0.12700991190964633 0.22181268347993335 1.1641630896968942 0.06167237000214597 0.04629681996891471 1.0007772899535371e-07 6.999662558390344 0.4257251651478543 ELPESGIQLGT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 ELPESGIQLGTPR 13 0 A0A087WW69;F8W8L6;A0A087WTA5;E7ERK9;Q9UI10-3;Q9UI10;Q9UI10-2 A0A087WW69 EIF2B4 Translation initiation factor eIF-2B subunit delta 1 ELPESGIQLGT(1)PR 116.58 0.00066453 13566000.0 8924.5 8506.9 9028.5 15967.0 15379.0 14577.0 12352.0 11553.0 11481.0 11714.0 True False 11762.305358868241 11256.589063503632 8908.776190882894 12286.054837690888 13243.891310863237 13665.497885624438 13451.304071005328 9767.74931152928 12087.862221073961 11303.89642546411 1.0405531788464977 0.9958149508647381 0.7881155183635825 1.0868867136834592 1.1716217853012993 1.2089192408770117 1.18997056985623 0.86410463647965 1.0693535897802304 1.0 13.464532531371283 -5.94372064352528 24.995151764081683 1.0924283542227136 0.9453550722440969 0.250566347501497 0.11264836071954448 123.73396532181404 54952.42480694315 0.033956701584104056 0.050365923554771395 1.1383592909388137e-06 5.94372064352528 -0.1470732819786167 ELPESGIQLGT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELPESGIQLGTPR 13 0 A0A087WW69;F8W8L6;A0A087WTA5;E7ERK9;Q9UI10-3;Q9UI10;Q9UI10-2 A0A087WW69 EIF2B4 Translation initiation factor eIF-2B subunit delta 1 ELPES(0.001)GIQLGT(0.999)PR;ELPESGIQLGT(1)PR 139.64 0.00016942 13428600.0 21737.3 17048.6 23206.0 23013.0 24808.0 21257.6 22170.4 15655.2 18330.9 14120.6 True False 25416.99555875503 18741.0723377278 23759.31904924509 21723.656219152657 19947.05048571807 20142.814034133928 20070.259212203975 15244.267588055509 18598.954733844308 16680.5530013919 1.5237501752270515 1.1235282389117411 1.4243723842526386 1.3023342941531937 1.195826690161507 1.2075627248361083 1.2032130595747768 0.9138946164904399 1.1150082813376947 1.0 14.025879498016728 -7.104504323141948 0.6964548432896377 0.9937229033534822 1.3500381873153442 0.5697017999668316 0.11373738224112838 0.5242664408856428 0.521970842221933 0.0895936804210785 0.06663557056090962 7.861323656314255e-08 7.104504323141948 0.35631528396186196 ELPESGIQLGT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 ELPESGIQLGTPR 13 0 A0A087WW69;F8W8L6;A0A087WTA5;E7ERK9;Q9UI10-3;Q9UI10;Q9UI10-2 A0A087WW69 EIF2B4 Translation initiation factor eIF-2B subunit delta 1 ELPES(0.001)GIQLGT(0.999)PR;ELPESGIQLGT(1)PR 93.243 0.010314 13471800.0 28192.9 28525.3 32332.5 22047.7 25975.3 23921.9 18885.8 17568.3 25436.7 20743.0 True False 27790.864076055343 28459.251420439206 29674.246657059277 23669.161406971143 24447.483923404678 22898.816101672557 19863.614315070903 18384.587354232346 22571.75098567421 24328.399911689874 1.1423219026707032 1.169795445805889 1.2197368821942418 0.9729025128199259 1.0048948558946362 0.9412380668187554 0.8164784526386535 0.7556841971098351 0.9277943090218774 1.0 14.57035381633291 -6.209049620311533 1.1128281850522295 0.862800138357153 1.1827569118171797 0.7063465481649429 0.07662137743685117 0.25755554241403406 0.6601932750246753 0.03256078457320243 0.051609577071549534 6.179457927147192e-07 6.209049620311533 0.3199567734600267 ELPGFLQSGK ddPTM_PC-9_Lapatinib_30min_R1 1 ELPGFLQSGK 10 0 P25815 P25815 S100P Protein S100-P 0 133.23 0.00011223 0.0 37701.0 33194.0 37435.0 35424.0 34818.0 35387.0 35151.0 30309.0 34667.0 29889.0 False True 37163.376826483356 33117.14133243329 34357.23880327886 38029.19913099984 32770.07369482176 33873.58050112601 36970.94678483609 31717.26678844441 30762.437400306168 35055.273825410906 1.0601365435503838 0.9447120994509904 0.9800875889428639 1.084835318086524 0.9348115167500803 0.9662905692829502 1.0546472114000873 0.9047787487386038 0.8775409244701736 1.0 15.097343883683013 -7.781085509817938 24.998731180828972 0.9183698341674345 0.9995115299409084 0.27503056773015455 0.05583967002172099 308.88838394015096 393039.50770198955 0.02963791059973463 0.014269209340625501 1.6554439850001124e-08 7.781085509817938 0.08114169577347397 ELPPAAAIGATSLVAAPHS(ph)SSSSPSKDSSR ddPTM_PC-9_AZD4547_30min_R2 1 ELPPAAAIGATSLVAAPHSSSSSPSKDSSR 30 1 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 ELPPAAAIGATSLVAAPHS(0.19)S(0.19)S(0.19)S(0.19)S(0.19)PS(0.016)KDS(0.02)S(0.016)R 81.113 3.3476999999999997e-07 8463700.0 7706.4 4064.6 40392.0 86985.0 57741.0 40288.0 20970.0 64072.0 29065.0 49224.0 True False 10156.874896922202 5378.402462414845 39856.375688336055 66931.95215485318 49724.65883220982 37768.784991153 22836.289375727167 54171.1446280883 30601.31656262646 47500.68274261953 0.21382587176602924 0.11322789804006596 0.8390695330485283 1.4090734762176191 1.0468198762876906 0.795120886910228 0.4807570766817111 1.1404287580793815 0.6442289835798449 1.0 15.535660629462773 -5.295534557789488 5.564861802240362 0.9297980734849498 0.16015385874333002 0.6030182706254799 0.24570040754795702 0.1177380092401931 10.680752175591161 0.06788707861007295 0.15151331471620477 5.063670551543437e-06 5.295534557789488 -0.7696442147416198 ELPPDQAEYCIAR ddPTM_PC-9_Lapatinib_30min_R1 1 ELPPDQAEYCIAR 13 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144;P12814-4;P12814-3;P12814;P12814-2;H9KV75;H0YJW3 O43707;P12814-4 ACTN4;ACTN1 Alpha-actinin-4;Alpha-actinin-1 0 148.18 0.0005262 2102000.0 3843.2 1267.4 4107.6 4139.8 3990.2 6074.4 6083.6 5384.9 5151.1 5291.0 False True 3788.3952632434357 1264.4654131688244 3769.888983794529 4444.254701967966 3755.504281035036 5814.612072118002 6398.579040716583 5635.10211254394 4570.928874512277 6205.5423001856625 0.6104857690084703 0.20376388589454833 0.6075035510887966 0.7161750717314422 0.6051855098824603 0.9370030516017973 1.031107150864985 0.9080756910440115 0.736588142244316 1.0 12.599341577145333 -6.117684368515717 0.971079019452278 0.9231879788228974 0.4085731938430443 0.6401643861496342 0.14193334689081868 0.3607146591237094 0.7060208565349427 0.06394214655998795 0.11979885005414792 7.626330662414207e-07 6.117684368515717 -0.514614784979853 ELPPLS(ph)PSLSR ddPTM_PC-9_AZD4547_30min_R2 4 ELPPLSPSLSR 11 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 ELPPLS(0.891)PS(0.109)LSR;ELPPLS(0.923)PS(0.077)LSR;ELPPLS(0.918)PS(0.082)LSR;ELPPLS(0.963)PS(0.037)LSR 187.78 0.00069335 140448000.0 263449.0 280702.0 462364.0 614866.0 534066.0 526731.0 488759.0 691017.0 495256.0 518967.0 True False 347220.30192038603 371433.43207321066 456232.75125672895 473118.14328500314 459920.15455019707 493794.42730279564 532257.6041483555 584236.200640963 521434.2210748366 500798.12329125975 0.6933338720170199 0.7416829552637686 0.9110113038330777 0.9447282673019161 0.9183743571712859 0.9860149316406467 1.0628186875987937 1.166610203731088 1.0412064199601145 1.0 18.933869630310646 -4.887064524226002 0.4697971773365273 1.0812677470399021 0.4208108662747472 0.84482353621886 0.05335723784590519 1.6715860560812246 0.3075952124648278 0.03972072051596084 0.6096556216094587 1.2969865601056944e-05 4.887064524226002 -0.660456880765155 ELPPLS(ph)PSLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 ELPPLSPSLSR 11 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 ELPPLS(0.858)PS(0.142)LSR;ELPPLS(0.712)PS(0.287)LS(0.001)R;ELPPLS(0.908)PS(0.091)LSR;ELPPLS(0.918)PS(0.082)LSR;ELPPLS(0.987)PS(0.004)LS(0.009)R;ELPPLS(0.801)PS(0.199)LSR 184.98 0.00030349 121376000.0 176048.4 201217.3 328267.0 306727.0 405587.0 317666.0 299242.0 291468.0 292685.0 230938.5 True False 205849.91700560416 221192.8237451913 336094.1302395296 289542.08061235136 326115.13888064167 301007.0357409674 270895.6314355332 283817.27383587306 296964.9644193802 272805.8219418401 0.754565703694878 0.8108068301868856 1.231990314016033 1.0613486125456637 1.1954112143184636 1.1033746772645472 0.9929979848204481 1.0403636983098568 1.0885580164879713 1.0 18.05751490764419 -5.1559014619465104 6.163003045037784 1.0900838116096123 0.7711423020523184 0.7400203671891132 0.07286148605539643 0.11136554886228033 5.4831598983796015 0.018891281131743876 0.05169214253945232 6.983908455743847e-06 5.1559014619465104 -0.31894150955729395 ELPPLS(ph)PSLSR ddPTM_PC-9_Lapatinib_30min_R1 4 ELPPLSPSLSR 11 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 ELPPLS(0.857)PS(0.143)LSR;ELPPLS(0.904)PS(0.096)LSR;ELPPLS(0.904)PS(0.096)LSR;ELPPLS(0.746)PS(0.254)LSR 166.24 0.0003137 130579000.0 422156.0 435531.0 451942.0 400567.0 418232.0 367349.0 338855.0 293898.0 420836.0 303109.0 True False 416135.9780260705 434522.5547284441 414785.07330657094 430026.0334323406 393632.41603574925 351638.33960234415 356399.25386975164 307553.574007399 373437.01808045834 355500.9867826447 1.170562089833237 1.2222822745471411 1.1667620871054651 1.2096338671916569 1.1072611066377105 0.9891346372474004 1.0025267639767654 0.865127202010944 1.0504528312569208 1.0 18.439494038850988 -6.6269058481585175 2.2248308008228865 0.9695227280691194 1.1934525925677901 0.8176063160551572 0.047016566980608326 0.11503094053742367 1.16107027014638 0.0166873984994351 0.016782472092018136 2.3609900229310766e-07 6.6269058481585175 0.2239298644986707 ELPPS(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELPPSPEK 8 0 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816-3;P27816;P27816-6;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 ELPPS(1)PEK 88.056 0.029651 0.0 23692.0 46644.0 33086.0 33991.0 35596.0 23544.0 27994.0 19700.0 23275.0 19955.0 True False 27702.587661670208 51274.508060543114 33874.89571935376 32086.594470308857 28621.21932802407 22309.311193156776 25342.205660991123 19182.89587387536 23615.35284302604 23572.68353630693 1.1751987260594388 2.1751663522555464 1.4370402787268253 1.361176992042026 1.2141689037627525 0.9464052388772669 1.075066638974674 0.8137764987312385 1.001810116640025 1.0 14.524828385237432 -6.159016669406292 1.2390869274913436 0.9541977433041647 1.677706034336764 0.5620929284744931 0.24208540407874762 0.307220581921794 0.9617076325736886 0.09042029747871874 0.14494549610779764 6.933991909543343e-07 6.159016669406292 0.7235082910325993 ELPPS(ph)PEKK ddPTM_PC-9_AZD4547_30min_R2 11 ELPPSPEKK 9 1 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816-3;P27816;P27816-6;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK 123.01 0.0022358 490494500.0 851665.0 924855.0 701360.0 589985.0 686999.0 860863.0 940952.0 796444.0 934499.0 847487.0 True False 1122476.7542675238 1223796.292224741 692059.5081395172 453973.07342738524 591621.0473159322 807033.1005222135 1024694.9051344424 673371.8802624111 983894.709322479 817816.7380849659 1.372528467558591 1.4964187393503758 0.8462281045507491 0.5551036708913879 0.7234151855356947 0.9868141148737017 1.2529639678614444 0.8233774743217008 1.2030748008733696 1.0 19.641418064942393 -5.261236001267311 24.999998523337926 0.9112359336742607 1.4344736426026485 0.5114367980690927 0.19931519807586948 14.450747163933647 1776025.345929954 0.055990945851793525 0.13058851968865168 5.479791050282931e-06 5.261236001267311 0.5232377089283878 ELPPS(ph)PEKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 10 ELPPSPEKK 9 1 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816-3;P27816;P27816-6;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK 143.0 0.0009247999999999999 474538800.0 961677.0 1248991.0 809981.0 964076.0 988293.0 730739.0 1060804.0 863188.0 723715.0 746591.0 True False 1124469.9221134593 1372982.5721860435 829294.0189100471 910061.947296565 794644.0811706622 692417.7604475103 960316.9655641239 840530.2296232838 734297.9627407329 881942.0382888941 1.2749929964729965 1.5567718881502066 0.9403044450846312 1.031884078303182 0.9010162195152829 0.7851057443535738 1.088866301721244 0.9530447502582419 0.832592087531496 1.0 19.750324318631257 -5.2720630719597645 24.828018534463208 0.9413699066993189 1.4158824381575792 0.7641189696836447 0.10540500238863697 247.21042981806318 577741.8938379529 0.026884595819319547 0.05691007452588694 5.344867310249194e-06 5.2720630719597645 0.47451253145826033 ELPPS(ph)PEKK ddPTM_PC-9_Lapatinib_30min_R1 9 ELPPSPEKK 9 1 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816-3;P27816;P27816-6;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK;ELPPS(1)PEKK 117.09 0.0027603000000000003 390562200.0 545760.0 964673.0 692793.0 857877.0 1012148.0 796861.0 924764.0 978362.0 737594.0 852824.0 True False 537977.3623198728 962439.3589378335 635834.2337983166 920968.1363737781 952615.4445995315 762781.1126037177 972643.7550149969 1023820.2702060785 654518.3965108448 1000233.49208345 0.5378517781875966 0.9622146894252734 0.6356858061950085 0.9207531478029545 0.9523930683577373 0.7626030508285344 0.9724167034129354 1.0235812720822797 0.6543656073218532 1.0 19.93190538787435 -4.751871135447309 24.952152593079113 0.8724835332502082 0.5378510971350186 0.36150288063990244 0.13474685026775055 416.99735852223574 1087371.1502301018 0.03215245112296279 0.40585918775144375 1.770634265807426e-05 4.751871135447309 -0.33463243611518967 ELPSFLGK ddPTM_PC-9_AZD4547_30min_R2 1 ELPSFLGK 8 0 P26447 P26447 S100A4 Protein S100-A4 0 109.01 0.009290799999999998 0.0 17799.0 20687.0 21203.0 28863.0 26846.0 21759.0 23983.0 29361.0 25791.0 24712.0 False True 23458.711757801095 27373.668193666264 20921.834366205905 22209.081278904752 23118.896295691167 20398.406290272487 26117.44053877274 24823.932098659352 27154.259606629934 23846.840401747384 0.9837241061118583 1.1478949719334914 0.8773419880259211 0.9313217560376416 0.9694741905513454 0.8553924103411951 1.0952159740566292 1.0409736334227477 1.138694231569571 1.0 14.541510507889402 -7.2997188187760065 24.9990436375633 1.0721354549744864 0.9646127335541882 0.29703112671295273 0.08110005325460734 767.7221153246155 501371.28354697424 0.0348882549704604 0.023522167338824007 5.015118292089398e-08 7.2997188187760065 -0.10752272142029817 ELPSFLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELPSFLGK 8 0 P26447 P26447 S100A4 Protein S100-A4 0 ; 126.28 0.016172 6556000.0 53406.0 51338.0 59228.0 63729.0 68467.0 61755.0 65187.0 53649.0 62599.0 47041.0 False True 62446.5809834189 56434.49735897785 60640.22014344082 60158.47074220567 55051.38284447198 58516.45908653572 59012.015446989644 52240.77059581416 63514.39194932708 55569.1609236489 1.123763251873093 1.0155722422463407 1.0912567174940695 1.0825873513703472 0.9906822764538709 1.053038378012156 1.0619562085537186 0.9401036425148133 1.1429791433524576 1.0 15.761996835773969 -6.227313852230833 24.480284675926125 1.0310688447811698 1.0747405561087031 0.14367519083212166 0.05574055302801194 1022.1221027475723 733228.0086455249 0.01546772456935442 0.01996821432713582 5.924969891567367e-07 6.227313852230833 0.043671711327533336 ELPSFLGK ddPTM_PC-9_Lapatinib_30min_R1 2 ELPSFLGK 8 0 P26447 P26447 S100A4 Protein S100-A4 0 ; 136.11 0.016255000000000002 22853000.0 122854.0 123255.0 121078.0 116684.0 120623.0 104479.0 122003.0 101086.0 114143.0 102099.0 False True 121102.07943133547 122969.61062026469 111123.43421459616 125265.33060641326 113528.19229394234 100010.67672244465 128319.71837473637 105782.82459258594 101287.01336092394 119746.67611163396 1.0113189222758712 1.0269146051755638 0.9279876304123984 1.0460860766576479 0.9480696749202923 0.8351854094823442 1.0715931543278094 0.883388399808023 0.8458440488694569 1.0 16.869626085105445 -6.509138698140449 24.825777165297367 0.9247927641724172 0.9991237387309723 0.20009848996005786 0.07167289848420037 1001.1359149933558 1808874.406210366 0.022407819207396838 0.0243582130125867 3.0964302521028337e-07 6.509138698140449 0.07433097455855509 ELPSLS(ph)PAPDTGLSPSKR ddPTM_PC-9_AZD4547_30min_R2 1 ELPSLSPAPDTGLSPSKR 18 1 Q9UBF8-2;A0A0B4J1S8;Q9UBF8;A0A0A0MSL0 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 ELPS(0.002)LS(0.995)PAPDT(0.001)GLS(0.001)PS(0.002)KR 82.367 0.0012396 4195600.0 14145.0 13426.0 17577.0 28440.0 25848.0 13833.0 16975.0 20749.0 19160.0 18650.0 True False 18642.8157657226 17765.691940260218 17343.91749539223 21883.597393619897 22259.451368957216 12968.020323238172 18485.74211506764 17542.7188145868 20172.75848408476 17997.0691766182 1.0358806527200193 0.9871436157694728 0.9637078862776978 1.2159533965703193 1.2368375734131591 0.7205628981015548 1.0271529177141978 0.9747542026108511 1.1208913121417134 1.0 14.135474362291728 -6.716888485800411 24.99999973265592 0.9707459430389955 1.0825204655758696 0.18465305853444813 0.12497833963406856 266.8145907589544 149723.69400722402 0.04327058811010114 0.04327039559864918 1.9191614622897456e-07 6.716888485800411 0.11177452253687403 ELPSLSPAPDT(ph)GLSPSKR ddPTM_PC-9_Lapatinib_30min_R1 1 ELPSLSPAPDTGLSPSKR 18 1 Q9UBF8-2;A0A0B4J1S8;Q9UBF8;A0A0A0MSL0 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 ELPSLSPAPDT(0.567)GLS(0.076)PS(0.356)KR 88.98299999999999 0.0012618 14100000.0 49660.0 57948.0 53205.0 54721.0 60234.0 58291.0 48707.0 47304.0 50251.0 49380.0 True False 48951.83929347137 57813.82496631454 48830.69027723927 58745.3648839048 56691.15454460037 55798.02981295776 51228.81013481866 49501.916531742194 44591.20321351102 57915.26720528591 0.8452320373478921 0.9982484370034623 0.8431402052269649 1.0143329681217998 0.978863731106574 0.9634424998019362 0.8845475917987825 0.8547300033388116 0.7699386597916135 1.0 15.821656090768137 -10.334267498712348 4.990204930982269 1.000000069192488 0.9116098192616602 0.11622840811895385 0.07642022236777525 109031077.51666461 18.35774340007019 129.7015801280923 0.01906497594458315 4.6316155280699397e-11 10.334267498712348 -0.08839024993082778 ELPSLSPAPDTGLS(ph)PSKR ddPTM_PC-9_AZD4547_30min_R2 1 ELPSLSPAPDTGLSPSKR 18 1 Q9UBF8-2;A0A0B4J1S8;Q9UBF8;A0A0A0MSL0 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 ELPSLSPAPDT(0.081)GLS(0.899)PS(0.02)KR 106.89 0.00014136 10258000.0 24390.0 18830.0 40805.0 60719.0 54738.0 44412.0 33597.0 52179.0 34074.0 50394.0 True False 32145.51265648456 24916.4292592805 40263.89903848662 46721.17264919851 47138.573546656626 41634.91061921879 36587.06791398692 44115.934504136305 35875.0820765503 48629.72139873982 0.6610260501578273 0.5123703887788709 0.8279689432794078 0.9607534508805398 0.9693366976163298 0.8561618167176608 0.752360220491311 0.9071804903508971 0.7377192598409572 1.0 15.569550705902786 -5.3587901568907625 5.190188338107182 0.8772646178056133 0.5884681436694882 0.6330034344290958 0.08876931881788849 0.1302075772248122 5.385177463060699 0.02355351697808706 0.05079821235412954 4.3773355887686785e-06 5.3587901568907625 -0.2887964741361251 ELPSLSPAPDTGLS(ph)PSKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ELPSLSPAPDTGLSPSKR 18 1 Q9UBF8-2;A0A0B4J1S8;Q9UBF8;A0A0A0MSL0 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 ELPSLSPAPDT(0.015)GLS(0.793)PS(0.191)KR;ELPSLSPAPDT(0.154)GLS(0.474)PS(0.372)KR;ELPSLSPAPDT(0.009)GLS(0.959)PS(0.032)KR 196.65 2.5776e-54 24895000.0 65148.0 66133.0 79835.0 93411.0 120415.0 94435.0 92233.0 85482.0 79930.0 66843.8 True False 76176.26966834748 72698.24718222917 81738.5691759234 88177.4845125481 96820.54515630995 89482.66235668359 83496.02253090663 83238.18807566552 81098.82503729619 78962.05180477032 0.9647199879847278 0.9206732287298196 1.0351626801443543 1.1167071079986937 1.2261655180350917 1.1332362864369956 1.0574196164170901 1.054154320628189 1.0270607612604714 1.0 16.2688718578203 -5.465752576034488 3.615588952454882 1.095934612181384 0.9441780583216463 0.46592514628753967 0.060970521646047625 0.20683712400326476 5.348244906552865 0.018130430165887428 0.039454803988488614 3.4217432875056124e-06 5.465752576034488 -0.15175655385973774 ELPSLSPAPDTGLSPS(ph)KR ddPTM_PC-9_Lapatinib_30min_R1 1 ELPSLSPAPDTGLSPSKR 18 1 Q9UBF8-2;A0A0B4J1S8;Q9UBF8;A0A0A0MSL0 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 ELPSLSPAPDT(0.125)GLS(0.154)PS(0.721)KR 84.15899999999999 0.0009048 12035000.0 52178.0 54631.0 51718.0 58424.0 59023.0 52705.0 40921.0 53366.0 47466.0 41597.0 True False 51433.93215172668 54504.50527601863 47465.945677253236 62720.69585675065 55551.38318368277 50450.930011355755 43039.68915200926 55845.579182161215 42119.87924086115 48786.98602548155 1.0542551680659802 1.117193532872697 0.9729222799797812 1.285603005358673 1.1386516714655863 1.034106308288959 0.8821961071653317 1.1446818861282586 0.8633425155401451 1.0 15.574208738394413 -6.942409561665526 5.105904715256862 0.9810544661480594 1.1145681633532925 0.29692458610973915 0.10219797057216164 0.2686922602051408 14.460254068579118 0.036284232126421186 0.03158388433505869 1.1418010507532723e-07 6.942409561665526 0.1335136972052331 ELPTVTTNVQNS(ph)QDK ddPTM_PC-9_AZD4547_30min_R2 1 ELPTVTTNVQNSQDK 15 0 Q96B01-3;Q96B01-2;Q96B01;H0YGT5;F5H1Y0 Q96B01-3 RAD51AP1 RAD51-associated protein 1 1 ELPTVTTNVQNS(1)QDK 176.08 2.0949e-28 0.0 12136.0 12637.0 10500.0 14249.0 13918.0 13646.0 12540.0 12582.0 14971.0 13431.0 True False 15994.99555551851 16721.663119996152 10360.763139421873 10964.113194855487 11985.725942167546 12792.713462799691 13656.035706801074 10637.741005596938 15762.336496097747 12960.784778078227 1.234107025877964 1.2901736589499617 0.799393193917238 0.8459451632435179 0.9247685342665447 0.9870323195580865 1.0536426567239037 0.8207636487868799 1.2161560249621646 1.0 13.661865455886465 -5.247138825561867 24.92287862335622 0.9491163195323657 1.2621404019285642 0.5202614906566391 0.11745765808034718 575.7532673940684 1003413.5391396171 0.029341577302197545 0.0768217459436273 5.660583152332366e-06 5.247138825561867 0.3130240823961985 ELPTVTTNVQNS(ph)QDK ddPTM_PC-9_Lapatinib_30min_R1 2 ELPTVTTNVQNSQDK 15 0 Q96B01-3;Q96B01-2;Q96B01;H0YGT5;F5H1Y0 Q96B01-3 RAD51AP1 RAD51-associated protein 1 1 ELPTVT(0.002)T(0.031)NVQNS(0.967)QDK;ELPTVTTNVQNS(1)QDK 203.52 9.6978e-13 10796300.0 50881.0 66372.0 51124.0 56057.0 63988.0 54663.0 50035.0 56646.0 52323.0 48237.0 True False 50155.42760956737 66218.31971188357 46920.78206434693 60179.61878067012 60224.35164524828 52325.19091567669 52625.56747686473 59277.979956389914 46429.832754383744 56574.70117823771 0.8865345563479599 1.1704581435306887 0.8293597860379985 1.0637196048296425 1.0645102915437838 0.9248867395839528 0.9301961191287375 1.047782466753745 0.8206818911532079 1.0 15.787869438894678 -6.786603311220468 24.98757621460666 0.9467887592717579 1.005960300639617 0.071590042877401 0.10438542255567024 654.2441044020062 649654.2200152136 0.034800709678141785 0.03070238486762234 1.634544274784809e-07 6.786603311220468 0.05917154136785907 ELPTVTTNVQNS(ph)QDKSIEK ddPTM_PC-9_AZD4547_30min_R2 2 ELPTVTTNVQNSQDKSIEK 19 1 Q96B01-3;Q96B01-2;Q96B01;H0YGT5;F5H1Y0 Q96B01-3 RAD51AP1 RAD51-associated protein 1 1 ELPTVTTNVQNS(0.998)QDKS(0.001)IEK;ELPT(0.001)VT(0.019)T(0.019)NVQNS(0.958)QDKS(0.004)IEK 94.671 0.0003543 37954000.0 65561.0 52306.0 58551.0 81413.0 69086.0 73669.0 56342.0 62180.0 56241.0 67339.0 True False 86408.03424648562 69212.89160042095 57774.575483456225 62644.49066831135 59494.60141116438 69062.46578418517 61356.32885108346 52571.509754253544 59213.784441722855 64981.48210639645 1.3297332016066783 1.0651171588714499 0.8890929170999808 0.9640360397711665 0.915562395356754 1.0628022560505281 0.944212518123588 0.8090229408460764 0.911240903135605 1.0 15.987741028774918 -4.822583509606869 2.54347133546469 0.935388711814539 1.3944631959872495 0.7758538644452537 0.06420360697854426 0.21477059300815476 1.9282146802371507 0.017661589679695135 0.2082814580160929 1.5045841775389132e-05 4.822583509606869 0.4590744841727106 ELPTVTTNVQNS(ph)QDKSIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELPTVTTNVQNSQDKSIEK 19 1 Q96B01-3;Q96B01-2;Q96B01;H0YGT5;F5H1Y0 Q96B01-3 RAD51AP1 RAD51-associated protein 1 1 ELPTVT(0.005)T(0.016)NVQNS(0.851)QDKS(0.128)IEK;ELPTVT(0.001)T(0.003)NVQNS(0.995)QDKS(0.001)IEK 99.92299999999999 0.00022388 27832000.0 67915.0 45228.0 51430.0 66297.0 71761.0 66206.0 64102.0 70974.0 69025.0 45902.0 True False 79411.66811760643 49717.936938561084 52656.28624936115 62582.59402777395 57699.947190648796 62734.04081099807 58029.79450170941 69111.00770316909 70034.36004252953 54223.66923996794 1.4645203696225073 0.9169046955958173 0.9710941178902832 1.1541563841947586 1.0641099726264653 1.1569493855785988 1.0701930598775489 1.274554243043143 1.2915828276502475 1.0 15.726635121186831 -7.751606578914898 24.911037168965258 1.2123014090716169 1.102192244649003 0.035574358627996294 0.15690938734231763 463.0464749118719 1173118.519191622 0.07239061608211898 0.04112546413355694 1.7717132009222652e-08 7.751606578914898 -0.11010916442261398 ELPTVTTNVQNS(ph)QDKSIEK ddPTM_PC-9_Lapatinib_30min_R1 1 ELPTVTTNVQNSQDKSIEK 19 1 Q96B01-3;Q96B01-2;Q96B01;H0YGT5;F5H1Y0 Q96B01-3 RAD51AP1 RAD51-associated protein 1 1 ELPTVTTNVQNS(0.984)QDKS(0.016)IEK 120.32 2.1185e-05 25913000.0 62224.0 53391.0 56732.0 54493.0 54659.0 46698.0 33942.0 47008.0 52633.0 30548.0 True False 61336.67434951592 53267.376419833236 52067.71395185297 58500.59700331909 51444.0650837286 44700.835398354844 35699.35068051852 49192.163291141085 46704.917289939 35828.181097348635 1.7119672969961337 1.486745204148115 1.453261437145803 1.6328095708896666 1.4358547798993786 1.2476445643974599 0.9964042155397151 1.3730019717574056 1.3035804737906516 1.0 15.128807183119205 -6.678202378069412 2.961557214232698 1.1908878385702442 1.5553962674068271 0.6686412758290152 0.1295414430366071 0.17082610257332978 3.026769547774597 0.046866039526949024 0.04568238494388143 2.0979620207620978e-07 6.678202378069412 0.36450842883658297 ELPVPGS(ph)AEEEPPSGGGR ddPTM_PC-9_AZD4547_30min_R2 2 ELPVPGSAEEEPPSGGGR 18 0 P16383-4;P16383;C9JII4;P16383-3;P16383-2 P16383-4 GCFC2 GC-rich sequence DNA-binding factor 2 1 ELPVPGS(1)AEEEPPSGGGR;ELPVPGS(1)AEEEPPSGGGR 121.51 6.7416e-05 8828500.0 16193.400000000001 12216.8 18952.6 30634.0 23039.1 15827.0 15451.7 19199.2 16854.1 18474.0 True False 21342.564356355764 16165.641687455018 18701.27614059114 23571.804590582 19840.518648813933 14837.33518802072 16826.871366090767 16232.40479372571 17744.973317672888 17827.23088304797 1.1971889799582136 0.9067948798950616 1.049028660888344 1.3222358954803566 1.1129332861044847 0.8322849064646174 0.9438858719270612 0.9105398869973244 0.9953858473077105 1.0 14.121795005027739 -6.739785577082829 24.60120604865832 0.9312947262259315 1.113478125392797 0.4123735178160223 0.10801835612045498 213.54221974404015 242607.78478219334 0.03748792127623246 0.03745351186955448 1.8205995159063016e-07 6.739785577082829 0.18218339916686555 ELPVPGS(ph)AEEEPPSGGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELPVPGSAEEEPPSGGGR 18 0 P16383-4;P16383;C9JII4;P16383-3;P16383-2 P16383-4 GCFC2 GC-rich sequence DNA-binding factor 2 1 ELPVPGS(0.999)AEEEPPS(0.001)GGGR 118.23 0.00010167 2565000.0 4905.5 5680.0 5320.7 5554.9 8285.3 5105.5 5123.3 6090.7 8406.5 3882.7 True False 5735.904261958604 6243.87286218774 5447.565666867115 5243.676962228787 6661.854941523705 4837.758592280915 4637.983934520108 5930.8255786300815 8529.429158964493 4586.602774563713 1.250577942735452 1.3613284535593275 1.187712547744076 1.1432594493050634 1.4524595368207778 1.054758571880272 1.0112024438308336 1.2930759148189443 1.8596398201882285 1.0 12.163210252037905 -8.014023101935566 24.99567687654659 1.4786659068395096 1.210274766095476 0.12087355244434383 0.22938447664876807 1046.8965643077267 1866045.6597561596 0.13604416715721893 0.055932154235140516 9.682263508918858e-09 8.014023101935566 -0.2683911407440336 ELPVPGS(ph)AEEEPPSGGGR ddPTM_PC-9_Lapatinib_30min_R1 1 ELPVPGSAEEEPPSGGGR 18 0 P16383-4;P16383;C9JII4;P16383-3;P16383-2 P16383-4 GCFC2 GC-rich sequence DNA-binding factor 2 1 ELPVPGS(1)AEEEPPSGGGR 120.08 8.240700000000001e-05 3020700.0 8221.9 7047.0 8200.3 7730.6 9019.3 7868.9 6922.6 7923.4 7686.5 5801.3 True False 8104.654198288203 7030.68310446639 7526.102988073397 8299.134112525613 8488.802506626054 7532.365490301818 7281.018355458054 8291.5500897938 6820.765427566663 6804.04697525365 1.1911520052352471 1.033309018887879 1.1061215502253097 1.2197349816527725 1.2476108024385881 1.1070419586603482 1.0701011298039462 1.2186203475593578 1.002457133581502 1.0 12.732177386088361 -8.28251223647769 23.492765827991075 1.001228398377141 1.1454998227615687 0.43879095978785143 0.0668376104828654 433.1146166790814 482841.7993930114 0.06721493455547548 0.017449617790729278 5.217804025919195e-09 8.28251223647769 0.14427142438442764 ELQAEQEDR ddPTM_PC-9_Lapatinib_30min_R1 1 ELQAEQEDR 9 0 Q00341;A0A024R4E5;Q00341-2;H0Y394 Q00341 HDLBP Vigilin 0 90.82700000000001 0.024661000000000002 0.0 11219.0 10281.0 17431.0 14662.0 10959.0 14228.0 10766.0 13050.0 14817.0 12393.0 False True 11059.015002687382 10257.194976162755 15997.89046560582 15740.29239099818 10314.413166222976 13619.501607087934 11323.410801557427 13656.350641367226 13148.153430072885 14535.11353736551 0.7608482021318856 0.7056838565309117 1.1006374614467194 1.082914994130215 0.7096204057648154 0.9370068952042372 0.7790383454830443 0.9395420686780848 0.9045786533605563 1.0 13.82725472031527 -1.523042737175019 0.01987310619989385 1.5883535083490394 4.798179371172313e-07 0.08186410980504832 0.13346902864862845 10932.843325951435 16.807955358840935 499.35643236357356 897.7613701992697 0.029988673979755208 1.523042737175019 -1.5883530285311023 ELQDAQEHDAR ddPTM_PC-9_Lapatinib_30min_R1 2 ELQDAQEHDAR 11 0 Q9H3S7 Q9H3S7 PTPN23 Tyrosine-protein phosphatase non-receptor type 23 0 ; 100.04 0.004190999999999999 0.0 32159.0 27139.0 29218.0 22561.7 23377.0 20754.4 19383.9 17722.4 27273.0 23299.0 False True 31700.40676276166 27076.161312915196 26815.808824741605 24220.962681624853 22002.010820950338 19866.7826928694 20387.50349584887 18545.847402802043 24201.22754257797 27326.20110603396 1.1600736831202572 0.9908498150859486 0.9813222379754918 0.8863640645708549 0.8051617103883505 0.7270232190629151 0.7460789524580882 0.6786837047286054 0.8856418588397946 1.0 14.737997289596144 -5.43655250099447 0.9718329532948005 0.7816833015411633 1.155423516293835 0.5916794889799661 0.0909444192945583 0.5612322260031198 0.8077158525874041 0.03275587803215685 0.17767883336733561 3.6597169629473392e-06 5.43655250099447 0.37374021475267183 ELQEAAAVPTT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 ELQEAAAVPTTPR 13 0 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 ELQEAAAVPT(0.02)T(0.98)PR 89.46600000000001 0.014897 10911000.0 19807.0 21918.0 27349.0 37760.0 39945.0 26816.0 25483.0 39135.0 28287.0 27988.0 True False 26105.213988806463 29002.56487014921 26986.33439048084 29055.01538618451 34399.32625088969 25139.19128084688 27750.937632887697 33087.58498283552 29782.193070944963 27008.148638884177 0.9665680657289578 1.0738449813029254 0.9991923086363672 1.075787006901814 1.2736647265545733 0.9308002416964442 1.0275024032167133 1.2250963746251995 1.1027113879278247 1.0 14.72110712857652 -5.9062812320679585 6.104053068260534 1.1000934011556827 1.0203979923983801 0.11438362100290533 0.09797339008209156 0.47746447798933217 25.678586634949987 0.028255150771672816 0.042315393750114075 1.2408485225492383e-06 5.9062812320679585 -0.07969540875730252 ELQELVQYPVEHPDK ddPTM_PC-9_AZD4547_30min_R2 2 ELQELVQYPVEHPDK 15 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 ; 172.57 8.0292e-05 8984600.0 45384.0 51338.0 51129.0 49578.0 55962.0 63549.0 55650.0 67051.0 55542.0 54411.0 False True 59815.16795415724 67932.00453069265 50450.99605290485 38148.55807246437 48192.64227443456 59575.27098398487 60602.74219166505 56689.808628698214 58477.836728759685 52506.08745141948 1.139204440047078 1.2937929262687071 0.9608599402799518 0.7265549562755136 0.9178486650528689 1.134635503723374 1.1542041148607176 1.0796806880944931 1.1137344176113957 1.0 15.68019707522062 -6.784577789156735 24.900202788061065 1.1050405773007228 1.0053327693027219 0.0866858222935889 0.14266198866160087 637.5719279210481 686112.6465880052 0.05751876832615474 0.05075736154625977 1.6421854913830518e-07 6.784577789156735 -0.09970780799800094 ELQELVQYPVEHPDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELQELVQYPVEHPDK 15 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 ; 150.39 6.2291e-05 8005800.0 65106.0 69147.0 66860.0 65662.0 71096.0 54025.0 65489.0 48046.0 52338.0 52507.0 False True 76127.15989788542 76011.45718339726 68454.19596796196 61983.17101907621 57165.249166906346 51191.83389442297 59285.407820699 46784.843408944966 53103.34423623189 62026.103454816686 1.2273406784829026 1.2254752910404616 1.1036352786182653 0.9993078327776668 0.9216321191052851 0.8253272580908454 0.9558138351200126 0.7542766803500027 0.856145095023023 1.0 15.920587875682976 -5.751476338056101 1.162896162588082 0.8654441069592155 1.2507966284705232 0.8184281560853665 0.0647950267415134 0.20100653423399817 0.5277898284200362 0.022595067809634207 0.062179437940578876 1.7722446008403128e-06 5.751476338056101 0.3853525215113077 ELQELVQYPVEHPDK ddPTM_PC-9_Lapatinib_30min_R1 2 ELQELVQYPVEHPDK 15 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 ; 181.97 8.2506e-06 26303000.0 161347.0 145228.0 177949.0 156666.0 169137.0 144104.0 174098.0 157476.0 152515.0 165886.0 False True 159046.1621925841 144891.73348878164 163318.7201230041 168187.74026245566 159188.6941961361 137941.00784283096 183111.94257194365 164792.90985440207 135337.15464585062 194559.17407079926 0.8174693532298193 0.7447180744921139 0.8394295509476881 0.8644554597114648 0.8182019427066852 0.7089925648668451 0.9411632396491877 0.8470066273741202 0.6956092165389333 1.0 17.56984948391436 -11.36762905011115 2.694031845509727 1.0718911129980266 0.8116207513057532 0.3961792929337853 0.0708116946322538 25778140.988469508 18156939.895005386 11962284.849471575 0.017454225645394797 4.289147187803134e-12 11.36762905011115 -0.26027036169227347 ELQGDGPPS(ph)SPTNDPTVK ddPTM_PC-9_AZD4547_30min_R2 2 ELQGDGPPSSPTNDPTVK 18 0 Q12873;Q12873-3;Q12873-2;A0A5F9ZHX5 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 ELQGDGPPS(0.498)S(0.498)PT(0.003)NDPTVK;ELQGDGPPS(0.497)S(0.497)PT(0.007)NDPTVK 330.13 2.381599999999999e-177 32149400.0 200996.0 199759.0 220224.0 230224.0 254781.0 244478.0 227564.0 252666.0 205996.0 241921.0 True False 264908.5470234843 264327.19024984696 217303.68586819447 177149.4137253425 219409.05599018492 229190.75201219035 247816.75515011797 213622.2753870738 216884.52801083075 233451.4194250213 1.1347480673963786 1.132257798649805 0.9308304331727866 0.7588277430981242 0.9398488838944651 0.981749233209527 1.0615345829144143 0.9150609403584452 0.9290349510189574 1.0 17.83276283487904 -5.260245823399019 23.58124087667675 0.9359886248726409 1.1335029783342394 0.5271054231703183 0.07339631244117491 37.74812883412827 745736.3852042968 0.02067642896006509 0.04877442508032398 5.492299056415841e-06 5.260245823399019 0.1975143534615985 ELQGDGPPS(ph)SPTNDPTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELQGDGPPSSPTNDPTVK 18 0 Q12873;Q12873-3;Q12873-2;A0A5F9ZHX5 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 ELQGDGPPS(0.714)S(0.257)PT(0.028)NDPTVK;ELQGDGPPS(0.741)S(0.259)PTNDPTVK 326.49 7.051999999999998e-177 39333000.0 267790.0 284460.0 260160.0 285650.0 306900.0 233440.0 291800.0 231817.0 231750.0 223688.0 True False 313121.55790641 312699.30886935344 266363.2010622937 269645.9565897949 246765.14810008398 221197.99545236645 264158.59155094717 225732.04938041474 235138.9053220743 264240.8636867661 1.184985371065043 1.1833874008224197 1.0080318287864947 1.020455174221032 0.9338644472211609 0.8371074494919032 0.9996886471885117 0.8542662411518601 0.8898657915408966 1.0 18.01149406471398 -5.436304368514447 1.0413990589315847 0.9108530012452997 1.232318712159217 0.7626097650366566 0.05594181427969128 0.3531265905816176 0.6008631871311081 0.0193529634826917 0.09968181832889582 3.6618085255889333e-06 5.436304368514447 0.3214657109139173 ELQGDGPPS(ph)SPTNDPTVK ddPTM_PC-9_Lapatinib_30min_R1 3 ELQGDGPPSSPTNDPTVK 18 0 Q12873;Q12873-3;Q12873-2;A0A5F9ZHX5 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 ELQGDGPPS(0.476)S(0.476)PT(0.048)NDPTVK;ELQGDGPPS(0.5)S(0.5)PTNDPTVK;ELQGDGPPS(0.36)S(0.36)PT(0.28)NDPTVK 292.35 8.705899999999998e-121 46983000.0 273060.0 360347.0 360072.0 321279.0 352216.0 343152.0 325466.0 343292.0 353413.0 293097.0 True False 269166.11432692857 359512.63866115385 330468.2700781148 344906.9294153252 331499.34736329893 328476.1888863817 342317.0369626312 359242.5995690613 313607.9063361241 343758.42592279677 0.7830095032707051 1.0458293136991943 0.9613386761095225 1.003341019174862 0.9643381001452135 0.9555436728702986 0.9958069712580971 1.0450437646864896 0.9122915474559334 1.0 18.3910355505449 -4.751065127028125 24.99524078100706 0.9867503554025909 0.7830090805496396 0.7129456827908399 0.03884239765402928 225.38339152623715 542991.9593606335 0.00911287830205426 0.12522395820242774 1.77392344245387e-05 4.751065127028125 -0.20374127485295135 ELQGDGPPSS(ph)PTNDPTVK ddPTM_PC-9_AZD4547_30min_R2 2 ELQGDGPPSSPTNDPTVK 18 0 Q12873;Q12873-3;Q12873-2;A0A5F9ZHX5 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 ELQGDGPPS(0.017)S(0.491)PT(0.491)NDPTVK;ELQGDGPPS(0.203)S(0.779)PT(0.017)NDPTVK 267.6 2.8985e-78 28481600.0 184155.0 182342.0 243044.0 265567.0 261321.0 277937.0 228088.0 265923.0 245006.0 243261.0 True False 242712.45933804542 241280.48560784492 239821.07775787142 204344.63111924956 225041.0898788014 260557.55545289133 248387.39013499575 224830.710652627 257956.51697033778 234744.5064328854 1.0339430857243004 1.027842948379404 1.0216259430396402 0.8704980330505527 0.958663924870769 1.1099623135478403 1.0581180105529366 0.9577677197609189 1.0988820181148258 1.0 17.84073187029341 -6.730163514211668 24.990606312768108 1.043129846615435 0.9809826973214144 0.21112394333136897 0.06025277790011207 349.9096165457853 279590.3196893791 0.021017295249768052 0.021015580841545395 1.8613861827909266e-07 6.730163514211668 -0.062147149294020654 ELQGDGPPSS(ph)PTNDPTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELQGDGPPSSPTNDPTVK 18 0 Q12873;Q12873-3;Q12873-2;A0A5F9ZHX5 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 ELQGDGPPS(0.161)S(0.649)PT(0.191)NDPTVK 267.69 2.8438999999999993e-78 5920800.0 51125.0 55062.0 47984.0 53503.0 57965.0 49527.0 50810.0 44878.0 44388.0 38420.0 True False 59779.452735222454 60528.19146791924 49128.12054033337 50505.400369066374 46607.174355234165 46929.71693269943 45996.90896745585 43700.00005217148 45037.09052615426 45385.241867447316 1.3171562004630282 1.3336536058284896 1.082469069655232 1.1128154944414101 1.026923564522486 1.0340303367725334 1.0134772246404453 0.9628680657867205 0.9923289746409224 1.0 15.469935625391686 -5.218588684456243 0.8171596025149235 0.9954720726658892 1.4460532167924194 0.9091317104465938 0.037921383534030864 0.3799941489776832 0.29861731870041613 0.014833018826253345 0.13815632542205117 6.045208934534681e-06 5.218588684456243 0.45058114412653016 ELQGDGPPSS(ph)PTNDPTVK ddPTM_PC-9_Lapatinib_30min_R1 1 ELQGDGPPSSPTNDPTVK 18 0 Q12873;Q12873-3;Q12873-2;A0A5F9ZHX5 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 ELQGDGPPS(0.026)S(0.948)PT(0.026)NDPTVK 229.93 2.6414e-35 27799000.0 151070.0 195930.0 210090.0 178170.0 208110.0 215250.0 202400.0 193920.0 220980.0 160120.0 True False 148915.71409715473 195476.3361229035 192817.21117085204 191273.21615769665 195869.37896000207 206044.2592722574 212879.2816491942 202930.23113976506 196090.90537743844 187796.52865351096 0.7929630817186603 1.0408942994018913 1.026734692879251 1.0185130552152017 1.0429872179447242 1.0971675608147897 1.1335634538908943 1.080585634861101 1.044166826636241 1.0 17.518810870012892 -4.225482499254827 1.5722451744707224 1.063457337731779 9.219727119178243e-14 0.7983584482141542 0.03900821362753781 2.4434042587436045 1.6826727092532445 0.011670988748400226 6.182148829433941 5.950007329936257e-05 4.225482499254827 -1.063457337731687 ELQGDGPPSS(ph)PTNDPTVKYETQPR ddPTM_PC-9_AZD4547_30min_R2 1 ELQGDGPPSSPTNDPTVKYETQPR 24 1 Q12873;Q12873-3;Q12873-2;A0A5F9ZHX5 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 ELQGDGPPS(0.287)S(0.495)PT(0.211)NDPT(0.007)VKYETQPR 54.596000000000004 0.031537 0.0 17771.0 13987.0 24216.0 50577.0 43553.0 20268.0 13599.0 27159.0 16600.0 18164.0 True False 23421.808340237265 18508.0242193073 23894.88001754669 38917.254056860525 37506.41772950302 19000.63875597421 14809.284655246245 22962.20060173321 17477.442110428325 17528.083888691322 1.3362446510966566 1.0559068713293989 1.3632340060263555 2.220279997745159 2.1397899489573535 1.0840111718219778 0.8448889650055145 1.3100234314001569 0.9971108206359242 1.0 14.0973806736861 -6.949123672260263 23.288838957343042 1.0496422168812332 1.6104817309618222 0.40653559464416444 0.3479738457550796 65.0292587196872 29766.754405787273 0.13994923107846402 0.12342356765116853 1.1242847704098028e-07 6.949123672260263 0.5608395140805891 ELQGDGPPSSPT(ph)NDPTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELQGDGPPSSPTNDPTVK 18 0 Q12873;Q12873-3;Q12873-2;A0A5F9ZHX5 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 ELQGDGPPS(0.325)S(0.193)PT(0.481)NDPTVK 147.52 0.00031196 4704400.0 38101.0 41318.0 42716.0 44911.0 52692.0 44532.0 52985.0 37426.0 42388.0 43537.0 True False 44550.746770947866 45419.777978850885 43734.511441332106 42394.78227342655 42367.380852686925 42196.6635258944 47965.8772218195 36443.60715612486 43007.8443097825 51429.91346129761 0.8662419158934322 0.8831393039972834 0.8503710875236743 0.8243214779144001 0.8237886864143669 0.8204692694582992 0.9326454974091121 0.7086072035402052 0.8362418175590953 1.0 15.650320105686605 -5.4393406359988035 4.616731116955217 0.8383801900165136 0.8741223505367293 0.0027174625197892155 0.07262121827901814 0.8435304083431344 31.531101732643958 0.018436884057642326 0.03945646715138008 3.636297136903009e-06 5.4393406359988035 0.035742160520215616 ELRAPS(ph)PPVEHPR ddPTM_PC-9_AZD4547_30min_R2 3 ELRAPSPPVEHPR 13 1 Q86WR7;Q86WR7-2 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 ELRAPS(1)PPVEHPR;ELRAPS(1)PPVEHPR;ELRAPS(1)PPVEHPR 91.14 0.0022173 114915000.0 83787.0 55045.0 111305.0 177111.0 135322.0 87737.0 62904.0 88389.0 85249.0 110038.0 True False 110429.52312213503 72837.21978635657 109829.022974605 136280.7952876728 116534.87612774815 82250.79152027378 68502.33413880508 74730.51102715835 89755.08810071717 106185.60311296076 1.0399670000900176 0.6859425162267241 1.034311806448642 1.2834206454776798 1.0974639942834603 0.774594569404809 0.645118849736456 0.7037725344711719 0.8452660762799951 1.0 16.696228649943137 -6.7732866521532005 24.283926192549373 0.7659466036142256 1.0237218150185212 0.33332094514255795 0.1633905251924264 186.97893221972052 383256.67216725694 0.061782288295601465 0.05494446362854803 1.6854401985818e-07 6.7732866521532005 0.2577752114042956 ELRAPS(ph)PPVEHPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ELRAPSPPVEHPR 13 1 Q86WR7;Q86WR7-2 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 ELRAPS(1)PPVEHPR;ELRAPS(1)PPVEHPR;ELRAPS(1)PPVEHPR;ELRAPS(1)PPVEHPR;ELRAPS(1)PPVEHPR 81.992 0.004640999999999999 75040900.0 76146.0 37931.6 68255.09999999999 111615.0 101069.2 129479.2 86986.2 132060.0 119618.6 78939.0 True False 89036.01384794616 41697.19856678882 69882.56044290835 105361.57341071234 81265.4157913229 122689.0828168954 78746.23741044907 128593.56492913575 121367.79572884165 93250.01581921999 0.9548096380010986 0.44715486855922343 0.7494107087165199 1.1298826331029534 0.8714788418788996 1.3157003968208192 0.8444635287045013 1.3790192291059218 1.3015311006931352 1.0 16.508816349660577 -5.720130137561882 4.56065306027981 1.1239572095509136 0.6785516225253165 0.44674070180642445 0.20536443990145672 0.1705221238625499 7.777239246761263 0.05591304428883225 0.09643153648234243 1.904889826843547e-06 5.720130137561882 -0.44540558702559707 ELRAPS(ph)PPVEHPR ddPTM_PC-9_Lapatinib_30min_R1 2 ELRAPSPPVEHPR 13 1 Q86WR7;Q86WR7-2 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 ELRAPS(1)PPVEHPR;ELRAPS(1)PPVEHPR 70.563 0.011764 59427000.0 506898.0 196665.0 286425.0 154418.0 214894.0 175063.0 182870.0 122178.1 217915.0 127134.0 True False 499669.5415662908 196209.63427556204 262876.24213247315 165774.41484334733 202254.35741785946 167575.96358178483 192338.11381021785 127854.9405590828 193371.11795331936 149108.9425045932 3.3510367196849966 1.3158810664190577 1.762981064159686 1.1117670882699793 1.356420037729321 1.1238491854814325 1.2899166916450568 0.8574599109315278 1.296844540007134 1.0 17.186007257344265 -2.979736278194848 1.2722650664354522 1.188326244093138 199.9999998884226 0.8718580939581687 0.2417813570414731 42.928040695607464 0.979853672956673 0.0668639711985739 24081.713602882737 0.0010477646014766721 2.979736278194848 198.81167364432946 up ELS(ph)DLEEENR ddPTM_PC-9_Lapatinib_30min_R1 2 ELSDLEEENR 10 0 Q5M775;Q5M775-4;Q5M775-2;Q5M775-5;Q5M775-3 Q5M775 SPECC1 Cytospin-B 1 ELS(1)DLEEENR;ELS(1)DLEEENR 95.618 0.0058472 8133700.0 54820.0 67863.0 45474.0 53617.0 45048.0 39849.0 50929.0 36300.0 49140.0 31496.0 True False 54038.25674724326 67705.86739299035 41735.30325471627 57560.1730410687 42398.3652077756 38144.75116255602 53565.85442248915 37986.630519665196 43605.33573285963 36940.041634217996 1.4628639913926622 1.8328584483855481 1.129812025335033 1.5582054186898922 1.1477617060534522 1.0326125655262415 1.4500756375128303 1.0283320981554533 1.1804354787859117 1.0 15.172897871897034 -5.62096523774384 0.7266405432126758 1.1325640944945161 1.6969695717052244 0.4233186962963661 0.2006667902864145 1.1190025730720337 0.9258492051428274 0.09486774543233333 0.43592178514601115 2.393507332371985e-06 5.62096523774384 0.5644054772107083 ELS(ph)DSCEGAFGGGR ddPTM_PC-9_AZD4547_30min_R2 1 ELSDSCEGAFGGGR 14 0 F8W9F9;H0Y7T5;Q9Y3S1-2;Q9Y3S1-4;Q9Y3S1;H0Y7R3 F8W9F9 WNK2 Serine/threonine-protein kinase WNK2 1 ELS(0.998)DS(0.002)CEGAFGGGR 136.33 3.2179e-05 0.0 6936.2 8284.4 10180.0 13529.0 11171.0 12047.0 9147.2 13469.0 9266.8 10459.0 True False 9141.767318077415 10962.170289728276 10045.006548506159 10410.09807096637 9620.099475496025 11293.699185574374 9961.28307952558 11387.675536829218 9756.624129452843 10092.833593471836 0.9057681604886875 1.0861340562296338 0.9952612866820064 1.0314346287944096 0.9531614076861843 1.1189820064881753 0.9869659483902177 1.1282932024357264 0.9666882980973294 1.0 13.30104365184657 -6.737715060679084 24.998695823464395 1.0448780586169661 1.0015616199586705 0.1008311301050604 0.06598071499700105 565.8128199327349 596204.6382696305 0.020174164923726014 0.02016382240236839 1.8293000208212285e-07 6.737715060679084 -0.0433164386582956 ELS(ph)DSCEGAFGGGR ddPTM_PC-9_Lapatinib_30min_R1 1 ELSDSCEGAFGGGR 14 0 F8W9F9;H0Y7T5;Q9Y3S1-2;Q9Y3S1-4;Q9Y3S1;H0Y7R3 F8W9F9 WNK2 Serine/threonine-protein kinase WNK2 1 ELS(0.609)DS(0.391)CEGAFGGGR 158.52 0.00042225 3012000.0 6795.2 7228.6 5193.9 3928.1 5615.4 5214.5 5408.6 8038.4 4497.7 4161.2 True False 6698.2992019129415 7211.862620823857 4766.877591033794 4216.985577757468 5285.113212301174 4991.4879905931975 5688.630843516949 8411.893409621942 3991.121663119308 4880.4578755495295 1.3724735204601528 1.4777020527017284 0.9767275351182194 0.8640553172037457 1.0829133960522261 1.02274993819738 1.1655936775965763 1.723586930596093 0.8177760703794449 1.0 12.252800789785644 -5.253608872287578 24.798132816561534 1.1006824223573728 1.4250878228892905 0.2472467998884168 0.2378401604857208 809.2305825456627 2562703.8112930832 0.06288730942010726 0.15979989269257142 5.57687779145729e-06 5.253608872287578 0.3244054005319177 ELS(ph)PAALEK ddPTM_PC-9_AZD4547_30min_R2 5 ELSPAALEK 9 0 O75683 O75683 SURF6 Surfeit locus protein 6 1 ELS(1)PAALEK;ELS(1)PAALEK;ELS(1)PAALEK;ELS(1)PAALEK;ELS(1)PAALEK 137.01 0.00096947 369833800.0 826071.0 772138.0 958480.0 1159103.0 1101352.0 956797.0 878249.0 1032962.0 826497.0 891729.0 True False 1088744.3946557972 1021716.5085184455 945769.9289402924 891889.7113128334 948448.2855193347 896968.3323366831 956411.4596062473 873341.4580053601 870183.9440929323 860509.8391311818 1.2652317790521181 1.1873385544900066 1.099080900568428 1.0364666047436881 1.1021934234673485 1.0423684791824248 1.111447442102339 1.0149116468989288 1.0112422944187576 1.0 19.71483216267511 -1.5228787452803811 0.48005115305129403 1.033846504861865 7.766546130609612 0.8284704800751954 0.03361076092241948 39.784164354506764 0.44580994690380477 0.01993752434336449 267.28605173786406 0.02999999999999699 1.5228787452803811 6.732699625747747 ELS(ph)PAALEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ELSPAALEK 9 0 O75683 O75683 SURF6 Surfeit locus protein 6 1 ELS(1)PAALEK;ELS(1)PAALEK;ELS(1)PAALEK;ELS(1)PAALEK;ELS(1)PAALEK 142.19 0.00067509 190709000.0 861541.8 844180.0 928336.0 945812.4 1108931.0 872422.0 981951.0 892921.0 811650.9 733721.4 True False 1007383.810513809 927984.6114087409 950471.0509738835 892821.5975931714 891643.931077793 826670.6545088437 888933.4925704029 869482.7698780026 823519.7589198543 866739.2816845921 1.1622685527254062 1.0706617676368753 1.0966054857079404 1.0300924585509563 1.0287337264151641 0.953770842025446 1.025606559382741 1.0031652980906534 0.9501354978618985 1.0 19.725238565246407 -4.7168656763022865 0.49895770769605113 0.9820654507408594 1.2757459310333974 0.789777052045681 0.028028841766880547 2.145377430162226 0.39209023747505545 0.017523646942676583 0.3768575238901677 1.919262260851947e-05 4.7168656763022865 0.293680480292538 ELS(ph)PAALEK ddPTM_PC-9_Lapatinib_30min_R1 6 ELSPAALEK 9 0 O75683 O75683 SURF6 Surfeit locus protein 6 1 ELS(1)PAALEK;ELS(1)PAALEK;ELS(1)PAALEK;ELS(1)PAALEK;ELS(1)PAALEK;ELS(1)PAALEK 134.75 0.0010972999999999998 367934600.0 770027.0 683015.0 792713.0 669196.0 760495.0 704350.0 660438.0 730761.0 710776.0 587968.0 True False 759046.2737743414 681433.5207318156 727539.1971006703 718410.9062124152 715764.1792906965 674226.5924200448 694632.2480920468 764714.8238341898 630720.9220769033 689597.485381886 1.100709167107818 0.9881612609919113 1.0550200842129998 1.0417829551895377 1.0379448801126643 0.9777103407601188 1.0073010166320033 1.1089292522734553 0.9146218416495849 1.0 19.3953949880841 -1.5228787452803376 0.20145244912359922 0.9953722318452124 1.3088501841340092 0.15635635196374853 0.050982736774192974 124.2380619281565 1.507872349272372 0.09014791768970785 12.319253673439647 0.029999999999999995 1.5228787452803376 0.3134779522887968 ELS(ph)PAALEKR ddPTM_PC-9_AZD4547_30min_R2 2 ELSPAALEKR 10 1 O75683 O75683 SURF6 Surfeit locus protein 6 1 ELS(1)PAALEKR;ELS(1)PAALEKR 59.155 0.033826999999999996 50578000.0 80412.0 47419.0 101190.0 158826.0 127750.0 99542.0 78290.0 87349.0 72108.0 97867.0 True False 105981.34332649593 62746.264420914595 99848.15448362844 122211.11953723892 110014.11762551423 93317.62300410423 85257.6583321736 73851.21913033586 75919.48166860035 94440.70611839656 1.1221998191503497 0.6643985099206279 1.057257602018062 1.2940513107137055 1.1649014725450475 0.9881080610210139 0.9027638804954451 0.7819850376568714 0.8038851549185063 1.0 16.527121207961628 -7.254445198105069 2.933634813643084 0.8467592126962011 1.0519785111863593 0.229232886700392 0.16074247016706159 0.4291324361900843 7.466806292130128 0.07826220849087255 0.053571592461636834 5.566148668452261e-08 7.254445198105069 0.2052192984901582 ELS(ph)PAALEKR ddPTM_PC-9_Lapatinib_30min_R1 1 ELSPAALEKR 10 1 O75683 O75683 SURF6 Surfeit locus protein 6 1 ELS(1)PAALEKR 69.26100000000001 0.017807 20305000.0 98205.0 48527.0 49252.0 33723.0 38787.0 48245.0 30711.0 24743.0 47033.0 34212.0 True False 96804.57869140865 48414.63871298997 45202.690678217965 36203.10191663018 36505.624918176014 46181.67381458799 32301.065309922902 25892.650108762406 41735.64826055327 40125.49861537548 2.4125451902624984 1.2065803637001589 1.1265328092620133 0.9022467798757198 0.909786200243942 1.1509308396953322 0.8050009700700798 0.6452916724339653 1.0401278414160517 1.0 15.292231699397101 -2.615050901906568 1.1096859105941872 0.9114858570789095 199.99999999704286 0.9064939585154995 0.14066649878134105 57.26164984085639 0.7116343390864815 0.04396021356337919 28323.850853421576 0.0024263256985561418 2.615050901906568 199.08851413996396 up ELS(ph)PAGSISK ddPTM_PC-9_AZD4547_30min_R2 4 ELSPAGSISK 10 0 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;O95453-4 O95453 PARN Poly(A)-specific ribonuclease PARN 1 ELS(1)PAGSISK;ELS(1)PAGSISK;ELS(1)PAGSISK;ELS(1)PAGSISK 140.45 0.00011719 815275000.0 3106520.0 3081100.0 3955000.0 5148490.0 4354560.0 3974810.0 3127840.0 4362820.0 3248560.0 3831570.0 True False 4094328.740369914 4077005.320805586 3902554.1158489045 3961585.173877572 3750004.509176972 3726264.502350192 3406211.700571032 3688646.416629982 3420272.2495333194 3697427.900539141 1.1073451195012887 1.1026598571972415 1.0554780839079656 1.0714435224821863 1.0142197792768763 1.0077990978017033 0.9212381666926769 0.99762497494329 0.9250409586173652 1.0 21.818090584519027 -6.366271259374772 0.9537413613747049 0.9592759812994576 1.1008322274469762 0.7927421212233532 0.02814503894844966 0.23133955540661225 0.45200982824787084 0.013254972871839648 0.01865319651555868 4.3025778848266194e-07 6.366271259374772 0.1415562461475186 ELS(ph)PAGSISK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ELSPAGSISK 10 0 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;O95453-4 O95453 PARN Poly(A)-specific ribonuclease PARN 1 ELS(1)PAGSISK;ELS(0.832)PAGS(0.164)IS(0.004)K;ELS(1)PAGSISK;ELS(1)PAGSISK;ELS(1)PAGSISK 155.47 0.00012613 436040300.0 1362412.0 1209514.0 1178579.0 1299071.0 1611536.0 1480415.0 1455430.0 1528577.0 1299088.0 1253525.0 True False 1593041.4427364254 1329586.556520449 1206680.7931457479 1226288.2635150051 1295767.0893079743 1402779.4312783375 1317561.1339992944 1488453.4734112078 1318084.704366964 1480779.1596015608 1.0758129815691568 0.8978965890350633 0.8148958508238556 0.8281371705994076 0.8750576214596588 0.9473252119889295 0.8897755789282015 1.0051826187314197 0.8901291565459541 1.0 20.497925065383377 -7.4424666910273425 1.5109111981951335 0.9595688761579148 0.8934660135950486 0.08899566898875777 0.07540979594812514 0.9982017511959712 4.398315133782871 0.05105789028291631 0.026051447371095993 3.610217017136086e-08 7.4424666910273425 -0.06610286256286613 ELS(ph)PAGSISK ddPTM_PC-9_Lapatinib_30min_R1 4 ELSPAGSISK 10 0 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;O95453-4 O95453 PARN Poly(A)-specific ribonuclease PARN 1 ELS(1)PAGSISK;ELS(1)PAGSISK;ELS(1)PAGSISK;ELS(1)PAGSISK 163.45 0.00011159999999999999 749041000.0 4196980.0 3464180.0 3876560.0 3675100.0 3959540.0 3627870.0 3211620.0 3250360.0 3927340.0 3163760.0 True False 4137130.295568134 3456158.904048586 3557844.200754336 3945379.113774215 3726647.641955151 3472714.4570780266 3377901.969022652 3401383.591622552 3485001.612476373 3710611.7005547835 1.11494562876239 0.9314256470252186 0.9588295644684118 1.0632691944523138 1.00432164362495 0.9358873246044074 0.9103356108421727 0.9166638457788515 0.9391986803564817 1.0 21.823225606470068 -6.755086162876152 5.816470505878454 0.9329792249613756 1.0099481382315998 0.3238656443591925 0.05287894667034268 0.19568356120394434 22.825217476966948 0.0180601820825743 0.017081912417758277 1.7575748811597787e-07 6.755086162876152 0.07696891327022415 ELS(ph)PQHK ddPTM_PC-9_AZD4547_30min_R2 2 ELSPQHK 7 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 ELS(1)PQHK;ELS(1)PQHK 66.962 0.029988 34354000.0 122282.0 127228.0 97821.0 84598.0 96090.0 110446.0 98898.0 111884.0 160216.0 165829.0 True False 161165.13237639374 168351.96292085727 96523.82962489393 65095.238126070915 82749.56213413429 103539.79416036769 107699.73040918737 94594.89863854797 168684.6906725534 160023.37718441914 1.0071349274841186 1.052046056538601 0.6031858052442858 0.40678580387071717 0.5171092098548168 0.6470291777497179 0.6730249811255307 0.5911317477666526 1.0541253011936658 1.0 17.28792315257727 -10.258957712810002 19.47365065781851 0.9999997176665151 0.7101479878964606 0.11646338545640311 0.21992643860463906 0.0 0.0 0.23004295180851356 0.05579361110208087 5.508613310811648e-11 10.258957712810002 -0.28985172977005447 ELS(ph)PQHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELSPQHK 7 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 ELS(1)PQHK 83.78299999999999 0.011625 17537000.0 38654.0 91284.0 68527.0 46672.0 107270.0 62019.0 48614.0 57038.0 76158.0 74752.0 True False 45197.358748700026 100346.07224506102 70160.94357009469 44057.11915266555 86251.2135441381 58766.61446179028 44008.929985119066 55540.81293675651 77271.66667321931 88303.94586349362 0.5118384949475445 1.1363713281871113 0.7945391667837173 0.49892582626796894 0.9767537871690493 0.6655038332334073 0.4983801069677128 0.6289731720778975 0.8750647088032876 1.0 16.430190285718815 -3.562627485635861 14.914038438364416 0.748848765776854 0.23530179544627994 0.0 0.22043046150320525 0.0 0.0 0.04945768265795811 0.0 0.0002737615898670208 3.562627485635861 -0.5135469703305741 ELS(ph)PQHK ddPTM_PC-9_Lapatinib_30min_R1 1 ELSPQHK 7 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 ELS(1)PQHK 74.165 0.019597999999999997 28799000.0 36249.0 86031.0 54272.0 71816.0 102970.0 66483.0 111800.0 136060.0 85916.0 100280.0 True False 35732.082612747545 85831.80050522894 49809.965655978354 77097.58821115308 96913.50704680906 63639.67706944253 117588.45695839863 142381.84431145014 76239.23534441122 117613.2643852991 0.30380997245080993 0.7297799355695578 0.4235063614321743 0.6555177990688419 0.8240015065760101 0.5410926854386083 0.9997890762829335 1.210593422906872 0.6482197033036406 1.0 16.843691250459294 -6.624203153551681 0.7121809513032255 0.9845123693575275 0.4775039940424671 0.4756516108899652 0.19279233344818578 0.6382044761430161 0.720094171620088 0.13273888250586927 0.1556472893570144 2.3757287122273733e-07 6.624203153551681 -0.5070083753150605 ELS(ph)PSSLK ddPTM_PC-9_AZD4547_30min_R2 2 ELSPSSLK 8 0 H7C1I9;O15021-2;O15021-3;O15021-6;O15021 H7C1I9 MAST4 Microtubule-associated serine/threonine-protein kinase 4 1 ELS(0.678)PS(0.203)S(0.119)LK;ELS(0.986)PS(0.012)S(0.002)LK 90.15 0.0096908 9454600.0 63447.0 76997.0 88578.0 108781.0 107555.0 95384.0 74484.0 104241.0 90987.0 89898.0 True False 83621.82622041718 101884.77449159959 87403.39784416297 83703.22109969646 92622.84478443959 89419.62340141345 81112.93170537255 88132.94866988019 95796.38706635807 86750.69838282155 0.9639325997285118 1.1744548042944045 1.007523852528093 0.9648708616767914 1.0676899034945504 1.0307654585881745 0.9350118583187639 1.0159335926145392 1.1042722289521967 1.0 16.404587751642396 ELS(ph)SPISPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELSSPISPK 9 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 ELS(0.958)S(0.024)PIS(0.018)PK 68.557 0.042736 950790.0 12593.0 10406.0 14718.0 16513.0 15674.0 13306.0 13006.0 15198.0 13078.0 11258.0 True False 14724.74617691259 11439.038909141831 15068.932938325837 15587.83014586832 12602.792216750455 12608.209936125717 11773.977524714244 14799.06860361207 13269.241008854764 13298.986281721036 1.1072081634636475 0.8601436731207375 1.1330888399394416 1.1721066414883978 0.9476505915396368 0.948057969911228 0.88532894728203 1.1127967418052638 0.9977633428416153 1.0 13.699028659706615 ELS(ph)SPISPK ddPTM_PC-9_Lapatinib_30min_R1 1 ELSSPISPK 9 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 ELS(0.888)S(0.055)PIS(0.057)PK 107.55 0.0024945999999999996 8904800.0 96053.0 122950.0 98136.0 110690.0 110920.0 85725.0 93863.0 93168.0 81924.0 74251.0 True False 94683.26660603727 122665.31682902532 90067.63689591493 118830.51185101522 104395.90367711037 82058.74158473538 98722.76686481384 97496.92540650617 72696.85642203495 87085.18641676167 1.087248824994341 1.4085669661656186 1.0342475064 1.364531865182336 1.1987791261938072 0.9422812875662763 1.1336344437773658 1.1195580949889372 0.8347786737704297 1.0 16.410139710306247 -6.665743322112562 6.453978794637224 1.0220951702428303 1.229807932647816 0.3926642188609717 0.1314801164482105 0.22839435982524542 12.986912174035867 0.04160385008678558 0.0414554175590867 2.1590200619630623e-07 6.665743322112562 0.2077127624049857 ELS(ph)VEEQIKR ddPTM_PC-9_Lapatinib_30min_R1 1 ELSVEEQIKR 10 1 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 ELS(1)VEEQIKR 77.74 0.0097882 3681600.0 15663.0 16534.0 15369.0 15360.0 14619.0 14684.0 14412.0 12804.0 15604.0 14028.0 True False 15439.642747757585 16495.716538845925 14105.420146055643 16489.625639457918 13759.139162059844 14055.999550075856 15158.182841542422 13398.920583300081 13846.513202595494 16452.721108864935 0.938424874863922 1.002613271670777 0.8573305323005483 1.002243065469158 0.8362834980923761 0.8543267376301847 0.9213176799900292 0.8143893338154606 0.8415941114527746 1.0 14.006038589990805 -6.271366196492276 24.982501503895605 0.8696883918038741 0.9472699324526546 0.2356404396776497 0.06252847813940969 914.9771096258947 2302689.6722938893 0.018371376431044383 0.021079802829579823 5.353450649481575e-07 6.271366196492276 0.07758154064878042 ELSAVTFPDIIR ddPTM_PC-9_Lapatinib_30min_R1 2 ELSAVTFPDIIR 12 0 A0A669KB68;A0A669KB56;A0A669KBA4;A0A669KB53;P42224;J3KPM9;A0A669KBI6;P42224-2 A0A669KB68 STAT1 Signal transducer and activator of transcription 1-alpha/beta;Signal transducer and activator of transcription 0 ; 162.36 5.5088e-12 2836200.0 18377.1 19203.8 22733.0 19368.0 19952.6 23591.0 18553.3 16345.599999999999 18849.9 18534.0 False True 18115.039184052595 19159.334780977955 20863.98049191767 20792.38732975399 18779.027296320903 22582.06792330697 19513.899092005882 17105.076248546535 16726.82576375319 21737.577204997342 0.833351344228374 0.8813923741498356 0.9598116798003212 0.9565181590234417 0.8638969798347037 1.0388493487726629 0.8977034978635867 0.7868897295791629 0.7694889640188507 1.0 14.407903531086786 -10.645860489331278 4.904102800760095 1.0000053699790223 0.892610823553899 0.15495471317570597 0.07798058125107689 4.922394943125052e-06 8.802274578930992e-07 0.08117586867703906 0.019687055560638555 2.260161697081515e-11 10.645860489331278 -0.10739454642512336 ELSDIAHR ddPTM_PC-9_AZD4547_30min_R2 6 ELSDIAHR 8 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ;;;;; 148.99 0.00068013 257377700.0 392331.0 378332.0 624696.0 912561.0 793697.0 638581.0 523720.0 756093.0 549988.0 611035.0 False True 517084.0970082503 500620.42031450354 616412.1228708839 702184.1603769041 683505.8717574754 598650.4291212136 570330.0654199241 639256.2001386737 579059.2428572443 589642.8506345799 0.8769445715347162 0.8490231328603925 1.0453991296723002 1.1908635195376422 1.159186227768011 1.0152763295220821 0.967246638886792 1.0841413568411782 0.9820508164120952 1.0 19.169481846481126 -5.285299920244868 6.440867820098604 1.0629605327886642 0.8623891733794998 0.5479765029966914 0.0697344287466494 0.12235867722761957 20.575254816182678 0.019914891602683008 0.04419171676199377 5.184418835160255e-06 5.285299920244868 -0.20057135940916437 ELSDIAHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 ELSDIAHR 8 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ;;;;; 146.81 0.000995 223676000.0 409539.0 463291.0 585024.0 634607.0 695758.0 652486.0 634254.0 541306.0 594022.0 462903.0 False True 478865.863936044 509283.4686964467 598973.190875875 599052.0272136537 559429.2144405922 618268.4855240444 574172.8695186914 527097.2910611146 602708.447970786 546823.6495618678 0.8757226654694366 0.931348651625621 1.0953681161299278 1.0955122875421224 1.023052340345602 1.1306542539252287 1.0500146984841212 0.9639255571397496 1.1021989419325495 1.0 19.06071611381057 -5.117434586995995 4.130409876591568 1.0584589693406874 0.8866526636020736 0.6200661611818346 0.048944986319286475 0.13929454095300345 3.915973165102169 0.0126399392706176 0.03911417404722494 7.630718156262446e-06 5.117434586995995 -0.17180630573861377 ELSDIAHR ddPTM_PC-9_Lapatinib_30min_R1 6 ELSDIAHR 8 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ;;;;; 146.81 0.000995 285556200.0 699867.0 541187.0 746309.0 555049.0 648012.0 692794.0 587353.0 599648.0 697173.0 499635.0 False True 689886.7682401114 539933.9147519289 684950.3548560487 595869.1550491856 609897.2082006105 663164.8156016928 617763.2643996984 627509.8352026507 618650.0351828437 585996.2440282115 1.177288720312853 0.9213948387115174 1.1688647526946834 1.0168480790134533 1.0407868897044472 1.1316878262615044 1.0542102798357826 1.070842759825677 1.0557235502571927 1.0 19.160531892089047 -8.848258354134073 1.8388767274036093 1.0000054153964177 1.0694735237759494 0.08394408836874556 0.07150666297173632 3.943401715359483 18.72742159114732 0.06279821987934021 0.017570235325910222 1.4182136004181472e-09 8.848258354134073 0.06946810837953166 ELSDQATAS(ph)PIVAR ddPTM_PC-9_AZD4547_30min_R2 3 ELSDQATASPIVAR 14 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 ELSDQAT(0.049)AS(0.951)PIVAR;ELSDQATAS(1)PIVAR;ELSDQATAS(1)PIVAR 213.0 3.1198e-15 78718200.0 55900.0 68462.0 82880.0 112178.0 104812.0 100343.0 88233.0 118369.0 88819.0 93735.0 True False 73675.03720776908 90591.00265262151 81780.95704717003 86317.09523282314 90260.66298681316 94068.53634747959 96085.56607003007 100077.7908990228 93513.79101241779 90453.36618071365 0.8145085176882889 1.001521629074952 0.9041228701625397 0.9542717853128119 0.9978695851571129 1.0399672264218816 1.0622663381931419 1.1064020624625606 1.0338342834648058 1.0 16.46488657263209 -6.315387363044772 1.1096154987538969 1.0609618421666247 0.9066158142299962 0.6180632190630072 0.04901860689634536 0.31917294648886185 0.82024132651456 0.020642392558411157 0.029244868442865883 4.837407091734421e-07 6.315387363044772 -0.15434602793662855 ELSDQATAS(ph)PIVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ELSDQATASPIVAR 14 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 ELSDQATAS(1)PIVAR;ELSDQAT(0.03)AS(0.97)PIVAR;ELSDQAT(0.013)AS(0.987)PIVAR;ELSDQAT(0.001)AS(0.999)PIVAR 189.04 3.1625e-06 72970000.0 79878.0 82809.0 105050.0 93604.0 118939.0 89173.0 90944.0 75164.1 77636.0 73951.9 True False 93399.7677375863 91029.73025438444 107554.79040434332 88359.67134826256 95633.7567607555 84496.61089990528 82329.12594245837 73191.12201794697 78771.2796271178 87358.79406708157 1.069151294211616 1.0420213697602556 1.2311844680657282 1.0114570867406025 1.0947238658917349 0.9672364620214599 0.9424251653386951 0.8378220281033705 0.9016983403712103 1.0 16.414665320451796 -6.918744591943252 1.7625241653297559 0.9033719627043056 1.0957790207296105 0.5922838960086592 0.06650986386053127 0.23302838111079302 1.4785074617310752 0.029320663097941298 0.023762435422462577 1.2057448289709554e-07 6.918744591943252 0.1924070580253049 ELSDQATAS(ph)PIVAR ddPTM_PC-9_Lapatinib_30min_R1 2 ELSDQATASPIVAR 14 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 ELSDQAT(0.001)AS(0.999)PIVAR;ELSDQAT(0.001)AS(0.999)PIVAR 208.38 5.838000000000001e-11 62000000.0 44018.0 61302.0 62821.0 45470.0 61879.0 55541.0 63206.0 55708.0 58680.0 48737.0 True False 43390.295248087445 61160.058985383665 57656.099876072716 48814.01548347344 58239.39887879481 53165.640902394654 66478.4974106668 58296.39705205258 52070.84047220606 57161.12551202955 0.7590874892579917 1.0699589701485592 1.0086592830286205 0.8539722590521865 1.0188637532432483 0.9301013656773773 1.1630018970965925 1.0198609024901744 0.9109484812584343 1.0 15.802746703167175 ELSEQIQR ddPTM_PC-9_Lapatinib_30min_R1 2 ELSEQIQR 8 0 P15311;E7EQR4 P15311 EZR Ezrin 0 ; 98.62899999999999 0.025099 13648500.0 52520.0 47736.0 46934.0 48626.0 50752.0 46663.0 40302.0 42893.0 55869.0 37174.0 False True 51771.055169011604 47625.47022489109 43075.26769047924 52202.11825158081 47766.86714227111 44667.33226676584 42388.640360799516 44885.965368594974 49576.44489334829 43599.47636875859 1.1874237830550736 1.0923404176252298 0.9879767207788079 1.1973106697443388 1.0955835051381189 1.0244924019035337 0.972228198391238 1.0295069828122576 1.137088080463107 1.0 15.412023187837622 -6.706319520275578 5.464381776082557 1.0306953932121876 1.1098314069188095 0.26224648259354133 0.0668038763732976 0.30322249456613787 18.856803224650484 0.023067021530244043 0.022696428239684804 1.9664390037089294e-07 6.706319520275578 0.07913601370662193 ELSESVQQQSTPVPLIS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 ELSESVQQQSTPVPLISPK 19 0 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;A0A087WYS3;Q9ULU4-4;Q9ULU4-18;Q9ULU4-8;Q9ULU4-15;Q9ULU4-17;A0A087WV57;Q9ULU4-2 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 ELSESVQQQSTPVPLIS(1)PK;ELSESVQQQSTPVPLIS(1)PK 136.34 2.0195999999999998e-05 14154900.0 48630.0 52447.0 45342.0 54056.0 58295.0 46681.0 53161.0 53123.0 54906.0 58331.0 True False 64093.32843316294 69399.46709301574 44740.73545406351 41594.22435687472 50201.745494945884 43762.02969052854 57892.22601349699 44914.06099509829 57808.21906717936 56288.84944457462 1.1386505331979309 1.2329167815261641 0.7948418895667414 0.7389425217836597 0.8918595066395439 0.7774546845840092 1.0284847991164068 0.7979211058368385 1.0269923730471842 1.0 15.780561539079203 -5.258156375245383 24.99988893816334 0.8715768995770596 1.1857836837250177 0.5762566420500667 0.10386786185664167 180.18966435815412 1372117.8022160663 0.02591389837666814 0.06296069291282767 5.518786900265754e-06 5.258156375245383 0.3142067841479581 ELSESVQQQSTPVPLIS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ELSESVQQQSTPVPLISPK 19 0 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;A0A087WYS3;Q9ULU4-4;Q9ULU4-18;Q9ULU4-8;Q9ULU4-15;Q9ULU4-17;A0A087WV57;Q9ULU4-2 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 ELSESVQQQST(0.001)PVPLIS(0.999)PK;ELSESVQQQSTPVPLIS(1)PK;ELSESVQQQSTPVPLIS(1)PK 149.12 6.3843e-05 12258500.0 122625.0 127822.0 97812.0 133885.0 135195.0 117004.0 138871.0 132426.0 107188.0 106041.0 True False 143382.9905458516 140511.32341383092 100144.20903407563 126383.85751102667 108704.51025542803 110868.10426622993 125716.13354102647 128949.9578169453 108755.42172022643 125265.39387990606 1.1446336941495203 1.121709029618678 0.7994563057861415 1.008928751959962 0.8677936251064263 0.8850657059564349 1.0035982776021328 1.0294140610021287 0.868200053915066 1.0 16.93462838172581 -5.144592861923781 7.789186373622728 0.9352584998281197 1.138061213828418 0.5470303502923235 0.07298958871541918 0.19466370894666793 11.76300485327561 0.018183576847802155 0.04874762994650825 7.168150880120133e-06 5.144592861923781 0.20280271400029837 ELSESVQQQSTPVPLIS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 ELSESVQQQSTPVPLISPK 19 0 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;A0A087WYS3;Q9ULU4-4;Q9ULU4-18;Q9ULU4-8;Q9ULU4-15;Q9ULU4-17;A0A087WV57;Q9ULU4-2 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 ELSESVQQQSTPVPLIS(1)PK;ELSESVQQQSTPVPLIS(1)PK 146.45 1.9163e-05 13735500.0 140215.0 129197.0 94483.0 127650.0 130775.0 122832.0 129638.0 126999.0 113472.0 117871.0 True False 138215.50838771838 128897.85228433988 86714.97245492693 137037.8068279167 123083.07161354237 117578.76169537716 136350.0213163942 132899.8371726437 100691.5884468672 138244.84529676527 0.9997877902139214 0.93238812635393 0.6272564613080437 0.9912688356209054 0.8903266617234395 0.8505110005582851 0.9862937097126225 0.961336655174031 0.7283569107456858 1.0 17.07686616246687 ELSESVQQQSTPVPLIS(ph)PKR ddPTM_PC-9_AZD4547_30min_R2 3 ELSESVQQQSTPVPLISPKR 20 1 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;A0A087WYS3;Q9ULU4-4;Q9ULU4-18;Q9ULU4-8;Q9ULU4-15;Q9ULU4-17;A0A087WV57;Q9ULU4-2 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 ELSESVQQQSTPVPLIS(1)PKR;ELSESVQQQSTPVPLIS(1)PKR;ELSESVQQQSTPVPLIS(1)PKR 139.45 6.8552e-05 34643000.0 107728.0 71578.0 117653.0 222848.0 220913.0 121806.0 95084.0 127041.0 119485.0 154229.0 True False 141983.2631183999 94714.18871592042 116092.84434689555 171473.83656727883 190243.0431859504 114189.45156454486 103546.29179788439 107409.73256175812 125800.73316653779 148829.48965365408 0.9539995295879449 0.6363939628922526 0.780039255775579 1.1521495972761928 1.27826174522718 0.7672501721955698 0.6957377334213154 0.7216965724448481 0.8452675169369508 1.0 17.183300890411196 ELSESVQQQSTPVPLIS(ph)PKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELSESVQQQSTPVPLISPKR 20 1 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;A0A087WYS3;Q9ULU4-4;Q9ULU4-18;Q9ULU4-8;Q9ULU4-15;Q9ULU4-17;A0A087WV57;Q9ULU4-2 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 ELSESVQQQS(0.001)T(0.003)PVPLIS(0.996)PKR;ELSESVQQQS(0.002)T(0.002)PVPLIS(0.995)PKR 58.361000000000004 0.0079472 57837000.0 25824.3 32815.0 22734.8 45210.0 46505.0 62997.0 55677.0 60459.0 48553.0 45200.0 True False 30195.843936825524 36072.656333220184 23276.883854209143 42677.03027279764 37392.67908893581 59693.326420119694 50402.871493427265 58872.015311605624 49262.99577174838 53394.402196996896 0.5655245249383811 0.6755887293228099 0.4359424002600468 0.799279110108624 0.7003108481480277 1.1179697489613822 0.9439729525853201 1.1025877786663714 0.9226247274010891 1.0 15.70440087902871 -6.4515525733057375 1.6410053909404245 1.0200907739530425 0.5868117887447215 0.7544025343754972 0.1079408471175079 0.16900578819998074 0.9156627490390304 0.038566016793688186 0.04470041248233645 3.5354722002429705e-07 6.4515525733057375 -0.433278985208321 ELSESVQQQSTPVPLIS(ph)PKR ddPTM_PC-9_Lapatinib_30min_R1 2 ELSESVQQQSTPVPLISPKR 20 1 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;A0A087WYS3;Q9ULU4-4;Q9ULU4-18;Q9ULU4-8;Q9ULU4-15;Q9ULU4-17;A0A087WV57;Q9ULU4-2 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 ELSESVQQQSTPVPLIS(1)PKR;ELSESVQQQSTPVPLIS(1)PKR 152.28 1.6890999999999998e-05 46817000.0 197219.0 90652.0 127656.0 115989.0 125585.0 134804.0 81509.0 78995.0 137459.0 101978.0 True False 194406.62089446513 90442.10086364244 117160.6164464101 124519.21798796124 118198.33720960963 129038.74716347229 85729.13719340005 82665.39608542567 121976.91991255907 119604.7614228561 1.625408709333495 0.7561747524740201 0.9795648187633195 1.0410891381466858 0.988241068361199 1.078876339272672 0.7167702704602985 0.6911547257986385 1.0198333114959892 1.0 16.867915298290626 -4.753477367127438 24.999569988742344 0.9159627952051898 1.6254099979914005 0.7080926782673682 0.13603927044299274 169.930337544921 533514.4310320175 0.03577608613504686 0.383207106464478 1.7640976964710933e-05 4.753477367127438 0.7094472027862108 ELSKEDLSPAFDHS(ph)PNK ddPTM_PC-9_AZD4547_30min_R2 2 ELSKEDLSPAFDHSPNK 17 1 K7EIY0;K7ENP9;K7EIE9;D3DUJ3;K7EQG9;P17706-3;P17706-2;P17706-4;P17706 K7EIY0 PTPN2 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 2 1 ELSKEDLSPAFDHS(1)PNK;ELSKEDLSPAFDHS(1)PNK 107.41 0.00027939999999999996 44704000.0 156722.0 163679.0 185855.0 144413.0 172808.0 192881.0 207344.0 201288.0 212059.0 187972.0 True False 206556.3359798922 216585.03583270186 183390.4412645003 111120.81400860871 148816.59208320832 180820.12057879736 225797.2143214486 170183.56473808613 223268.0058129709 181391.15749422353 1.1387343177765987 1.1940220175264007 1.0110219472541842 0.61260325775333 0.8204181181651451 0.9968519032387543 1.2448082775404266 0.9382131250995832 1.2308648828159166 1.0 17.468744603124804 -8.242144353297645 24.776055870897494 1.1154324980975403 0.9916581471704193 0.06602370807842939 0.18154363027394887 2061.48358577295 2647087.9738713964 0.13594500616746097 0.05119822926481723 5.726056733845683e-09 8.242144353297645 -0.12377435092712097 ELSKEDLSPAFDHS(ph)PNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ELSKEDLSPAFDHSPNK 17 1 K7EIY0;K7ENP9;K7EIE9;D3DUJ3;K7EQG9;P17706-3;P17706-2;P17706-4;P17706 K7EIY0 PTPN2 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 2 1 ELSKEDLS(0.001)PAFDHS(0.999)PNK;ELSKEDLSPAFDHS(1)PNK;ELSKEDLSPAFDHS(1)PNK 77.562 0.0035856 27290000.0 131618.0 149401.0 145904.0 154319.0 170270.0 124112.0 168549.0 160651.0 149677.0 117687.0 True False 153898.3278260047 164232.5439231883 149382.90470400124 145673.006738948 136906.81579342208 117603.34823331093 152582.81853091373 156434.08147380452 151865.74296393569 139022.72149022028 1.1070012597676766 1.1813359871159006 1.0745215106043637 1.0478359593125612 0.9847801447553517 0.8459289745783308 1.097538710905234 1.1252411102080824 1.0923807370194436 1.0 17.08496116675513 -5.543538513091179 2.800877281401619 1.0261264256453835 1.1438019997308326 0.26902182140187003 0.07594361990837008 0.38823188004419595 6.128975356433484 0.02380464966330818 0.05124296429041035 2.8606286697733804e-06 5.543538513091179 0.11767557408544915 ELSKEDLSPAFDHS(ph)PNK ddPTM_PC-9_Lapatinib_30min_R1 4 ELSKEDLSPAFDHSPNK 17 1 K7EIY0;K7ENP9;K7EIE9;D3DUJ3;K7EQG9;P17706-3;P17706-2;P17706-4;P17706 K7EIY0 PTPN2 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 2 1 ELSKEDLSPAFDHS(1)PNK;ELSKEDLSPAFDHS(1)PNK;ELSKEDLS(0.001)PAFDHS(0.998)PNK;ELSKEDLS(0.001)PAFDHS(0.998)PNK 124.2 1.9352e-05 47546700.0 244240.0 451577.0 411138.0 417149.0 461303.0 440008.0 427145.0 440683.0 429596.0 420039.0 True False 240757.0928118699 450531.4012013086 377335.82067857514 447827.5290282713 434170.0644965928 421189.8835487457 449260.4780634635 461158.74097238516 381210.3746335691 492642.18148321426 0.48870580283445175 0.9145205549489869 0.7659429802428156 0.9090320436629726 0.8813091546270408 0.8549610637900621 0.9119407451283608 0.9360926820841023 0.7738078243439209 1.0 18.910180635386318 -4.758189086808686 24.999998992437938 0.8781906346405245 0.4887052657806294 0.7538026286067263 0.06756105741919617 42.35343144455422 325712.72321697214 0.015705599946598755 0.10968775067230398 1.7450622075374865e-05 4.758189086808686 -0.3894853688598951 ELSLAGNELGDEGAR ddPTM_PC-9_Lapatinib_30min_R1 1 ELSLAGNELGDEGAR 15 0 P13489;H0YCR7 P13489 RNH1 Ribonuclease inhibitor 0 89.62899999999999 0.030777999999999996 0.0 6304.2 8246.1 7776.3 8533.8 8887.4 7754.1 8142.1 6601.5 10925.0 5459.1 False True 6214.300951951306 8227.006662088872 7136.962631386066 9161.404119922272 8364.660605300684 7422.475218689949 8563.658098398735 6908.229789960594 9694.51145464981 6402.698161206489 0.9705753411277969 1.284928081091772 1.1146804755889377 1.4308661581816544 1.3064274458511242 1.1592730176884207 1.3375077010947283 1.0789560301026035 1.5141290766115123 1.0 12.644464284068714 -4.757503028858311 24.722353177367946 1.2533754730028648 0.9705748672799581 0.227530908144833 0.1526750014435839 141.52140346302502 888684.6314533834 0.034776679969350494 0.25659422823870676 1.747821072715002e-05 4.757503028858311 -0.28280060572290666 ELSLT(ph)PITGAKPSATGYLGSVAAK ddPTM_PC-9_AZD4547_30min_R2 1 ELSLTPITGAKPSATGYLGSVAAK 24 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785;O95785-2 B9EGQ5 WIZ Protein Wiz 1 ELS(0.114)LT(0.846)PIT(0.039)GAKPSATGYLGSVAAK 72.316 0.00036954 7794900.0 9558.0 9969.2 13663.0 17385.0 15442.0 17796.0 8024.5 13678.0 12615.0 13335.0 True False 12597.245181249675 13191.548941668574 13481.819692754387 13377.156845572492 13298.144848322396 16683.213306755333 8738.664954483667 11564.37938917144 13281.803145967078 12868.145708858108 0.9789479748102361 1.0251320773114843 1.0476893872497761 1.0395559040308342 1.0334157810451499 1.2964737643024222 0.6790927886733665 0.8986826580002751 1.0321458465320468 1.0 13.651516556700054 -7.265020556275516 24.999986945345213 0.894037230008326 1.064065351228981 0.32195724471096376 0.11878870136312562 393.1955091385089 2744855.0928572877 0.04839405222439348 0.03407382321827311 5.432246186646824e-08 7.265020556275516 0.17002812122065503 ELSNS(ph)PLR ddPTM_PC-9_AZD4547_30min_R2 3 ELSNSPLR 8 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 ELS(0.02)NS(0.98)PLR;ELS(0.011)NS(0.989)PLR;ELS(0.003)NS(0.997)PLR 101.3 0.0046297 486390000.0 393421.0 504828.0 500579.0 432598.0 445872.0 530460.0 536132.0 626220.0 485762.0 425716.0 True False 518520.6943348425 668003.7785504012 493940.99538749194 332869.2146724742 383970.3691109438 497290.2523433049 583846.7093746943 529452.0881040308 511438.3876172226 410811.8124178654 1.2621854548997702 1.6260578648379467 1.2023534388662371 0.8102717707004239 0.934662435461765 1.2105062155259456 1.4212023406494043 1.2887947038034246 1.244945671369846 1.0 18.648118139714306 -1.522878749609067 0.01688375787078302 7.345746951693973e-11 2.6907315182804585 0.06489673760453973 0.2176594542411874 18467.542876958814 24.14683814938217 1496.1254460805096 2463.19117330825 0.029999999700981966 1.522878749609067 2.690731518207001 ELSNS(ph)PLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ELSNSPLR 8 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 ELS(0.03)NS(0.97)PLR;ELS(0.003)NS(0.997)PLR;ELS(0.021)NS(0.979)PLR;ELS(0.001)NS(0.999)PLR 120.63 0.0034073999999999997 636930000.0 494554.0 806810.0 707780.0 545866.0 638621.0 416840.0 627263.0 371046.0 424882.0 405514.0 True False 578272.224313255 886904.7647784683 724656.1594705974 515282.8977414496 513487.79942920804 394980.1765951187 567844.1076491493 361306.4356557346 431095.0954522268 479030.4781529428 1.2071720917277977 1.8514579034683074 1.5127558527481257 1.0756787328611945 1.071931375659283 0.8245408060841822 1.185402878411111 0.7542451934350162 0.8999324993149781 1.0 18.869757924304878 -5.816168450736631 3.123458566313365 0.9557175951733625 1.5688377690066273 0.6550659882006078 0.18441826844311848 0.13773410105781914 2.726120374209439 0.0519613400094715 0.08659270275007272 1.5269736727913869e-06 5.816168450736631 0.6131201738332648 ELSNS(ph)PLR ddPTM_PC-9_Lapatinib_30min_R1 4 ELSNSPLR 8 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 ELS(0.002)NS(0.998)PLR;ELS(0.031)NS(0.969)PLR;ELS(0.003)NS(0.997)PLR;ELS(0.132)NS(0.868)PLR 120.63 0.0034073999999999997 704760000.0 319634.0 540867.0 537120.0 474203.0 610208.0 529242.0 572437.0 580641.0 503412.0 474564.0 True False 315075.96054630325 539614.6556922689 492960.0669431574 509077.47051483527 574316.7651550861 506607.5533833598 602074.9869042475 607619.7005941836 446712.4393966291 556591.755083217 0.5660808980168879 0.9694981119718349 0.8856761934417337 0.9146335098670697 1.0318456209780162 0.9101959358122651 1.0817174013190876 1.0916793054243812 0.8025854413345385 1.0 19.08626001230386 -4.456922644136717 2.0981063887906752 0.9726775819651781 2.7684420811758247e-08 0.6452543400935554 0.08774685145200173 1.6245954214669607 3.2906057034607623 0.023117014582676995 4.195692946442562 3.492025093518571e-05 4.456922644136717 -0.9726775542807572 ELSNS(ph)PLRENS(ph)FGSPLEFR ddPTM_PC-9_Lapatinib_30min_R1 4 ELSNSPLRENSFGSPLEFR 19 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 ELS(0.264)NS(0.736)PLRENS(0.55)FGS(0.45)PLEFR;ELS(0.074)NS(0.922)PLRENS(0.855)FGS(0.149)PLEFR;ELS(0.075)NS(0.925)PLRENS(0.823)FGS(0.177)PLEFR;ELS(0.021)NS(0.834)PLRENS(0.581)FGS(0.564)PLEFR 86.825 0.0039020000000000005 38156600.0 187579.0 162571.0 202103.0 176516.0 176594.0 195218.0 149871.0 147392.0 196154.0 151155.0 True False 184904.08906222455 162194.57683783286 185486.8714801408 189497.5754801145 166207.08811716217 186868.98121538467 157630.58705556515 154240.37040095046 174061.07092680808 177281.9403486224 1.0429945018573992 0.9148962185255844 1.046281821574062 1.0689051299160548 0.9375297212469489 1.0540779328560457 0.8891519730976932 0.8700286678814491 0.9818319372211264 1.0 17.435686051302163 -7.266276461040852 24.97224495107828 0.9244222003681007 1.0073485850093962 0.2709108797732559 0.05949110293842447 510.34687202381093 2634737.1661339803 0.023838004715537365 0.016650799978443487 5.4165597593970675e-08 7.266276461040852 0.08292638464129543 ELSNS(ph)PLRENSFGS(ph)PLEFR ddPTM_PC-9_AZD4547_30min_R2 1 ELSNSPLRENSFGSPLEFR 19 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 ELS(0.078)NS(0.922)PLRENS(0.132)FGS(0.868)PLEFR 125.75 0.00088004 3958300.0 6440.7 7357.0 12641.0 16247.0 15035.0 11052.0 8217.5 11088.0 9453.5 11100.0 True False 8488.708625117675 9735.006376023723 12473.372080517329 12501.505163647756 12947.649772991019 10360.916692866938 8948.841580593129 9374.604376892301 9953.192710297239 10711.392378577051 0.7924934803149609 0.9088460241167045 1.1644958600773756 1.1671223237653918 1.2087737350455499 0.9672801001659626 0.8354508232273284 0.8751994181112862 0.9292155826728723 1.0 13.386858408386596 -6.994979610547155 24.75357530810845 0.8998233988710266 1.0570856264042927 0.21438926431814787 0.12421260790746191 188.44224110028298 929126.8174241128 0.04846534399938335 0.042595421468037874 1.0116269474623627e-07 6.994979610547155 0.15726222753326613 ELSNS(ph)PLRENSFGS(ph)PLEFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ELSNSPLRENSFGSPLEFR 19 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 ELS(0.076)NS(0.902)PLRENS(0.426)FGS(0.596)PLEFR;ELS(0.12)NS(0.877)PLRENS(0.035)FGS(0.968)PLEFR;ELS(0.006)NS(0.994)PLRENS(0.301)FGS(0.699)PLEFR 112.58 0.0038841 7231300.0 30389.3 24729.4 29224.4 35662.9 38272.0 36709.7 37179.1 33841.0 34543.1 27823.6 True False 35533.608273965685 27184.371401088993 29921.2205301542 33664.8233336818 30772.876337850787 34784.57870826655 33657.22649462581 32952.70960750337 35048.22748837522 32867.7984285036 1.0811070401098188 0.8270822111868062 0.9103506155193507 1.0242494156373736 0.936262171766392 1.0583178786352991 1.0240182824486839 1.0025834154722737 1.0663393705731354 1.0 15.004387203699567 -6.373610477607304 1.3416704667669166 1.0285235630499747 0.9371317649119899 0.19000456840419855 0.06798779174266939 0.6298460418613321 2.3101191503350647 0.026916629522728462 0.03433624646648223 4.2304787937693776e-07 6.373610477607304 -0.09139179813798481 ELSNS(ph)PLRENSFGS(ph)PLEFR ddPTM_PC-9_Lapatinib_30min_R1 1 ELSNSPLRENSFGSPLEFR 19 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 ELS(0.04)NS(0.934)PLRENS(0.071)FGS(0.955)PLEFR 70.50399999999999 0.02246 1447200.0 7584.9 7145.1 6833.2 5471.0 5921.9 6084.9 5040.5 5675.4 7461.2 4454.1 True False 7476.737935099693 7128.555959943633 6271.400672914789 5873.355590720985 5573.585484903358 5824.663011594697 5301.4724266440835 5939.099803066327 6620.84108608084 5223.985250284814 1.4312325890836037 1.364581946236349 1.2005012212798396 1.1243055463069629 1.0669221327911451 1.114984582178354 1.0148329623164698 1.136890614831373 1.267392760291555 1.0 12.350935108159947 -5.301044128953788 1.716695056462103 1.1026813702072211 1.4408894788733226 0.7411111792642434 0.06944595935286879 0.2234453391071828 1.148387753601734 0.020601221794811983 0.08759104517346349 4.999837287135482e-06 5.301044128953788 0.3382081086661015 ELSNS(ph)PLRENSFGSPLEFR ddPTM_PC-9_AZD4547_30min_R2 4 ELSNSPLRENSFGSPLEFR 19 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 ELS(0.093)NS(0.778)PLRENS(0.053)FGS(0.076)PLEFR;ELS(0.082)NS(0.91)PLRENS(0.006)FGS(0.003)PLEFR;ELS(0.105)NS(0.813)PLRENS(0.019)FGS(0.063)PLEFR;ELS(0.019)NS(0.981)PLRENSFGSPLEFR 85.176 0.00061827 1048113400.0 94705.0 74547.8 112045.2 166247.0 128309.0 113419.0 98009.3 131260.0 105495.0 119707.0 True False 124819.2200136276 98643.91848831603 110559.40743896691 127921.322640546 110495.51012455647 106326.892000387 106731.93783082742 110976.78305473321 111071.25032768885 115516.09436597502 1.0805353201968433 0.8539409077993495 0.9570909408406376 1.1073896095834843 0.9565377944175254 0.9204508911418435 0.9239572928485803 0.9607040790622605 0.9615218635750951 1.0 16.81773434464423 -6.498384995112606 24.96030894110366 0.947864000152616 0.9919893407195108 0.09249187637487677 0.06769450289468223 2033.3091570577867 2072041.9353047225 0.021522844525879065 0.02428678424471287 3.174059070504023e-07 6.498384995112606 0.04412534056689488 ELSNS(ph)PLRENSFGSPLEFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 ELSNSPLRENSFGSPLEFR 19 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 ELS(0.07)NS(0.93)PLRENSFGSPLEFR;ELS(0.08)NS(0.757)PLRENS(0.064)FGS(0.099)PLEFR;ELS(0.033)NS(0.966)PLRENSFGSPLEFR;ELS(0.017)NS(0.714)PLRENS(0.267)FGS(0.001)PLEFR;ELS(0.006)NS(0.982)PLRENS(0.003)FGS(0.009)PLEFR;ELS(0.008)NS(0.737)PLRENS(0.241)FGS(0.014)PLEFR;ELS(0.023)NS(0.966)PLRENS(0.005)FGS(0.005)PLEFR 111.72 0.00058606 536495900.0 86208.59999999999 66191.90000000001 95387.8 112254.5 114172.8 109279.4 102456.5 107026.8 96573.6 80805.09999999999 True False 100802.0132825369 72762.99438497261 97662.20691224595 105965.2442989992 91801.4594363024 103548.59588861107 92751.07859917621 104217.4599042682 97985.80620069885 95454.42497718021 1.0560224243835223 0.7622799509018852 1.0231291732739842 1.1101134842552531 0.9617307888895552 1.084796183239969 0.9716791926759784 1.091803338914701 1.0265192653365602 1.0 16.542524457688486 -5.486654018603471 24.991659455972012 1.0378145904727842 0.9050394686967396 0.27602909910304374 0.08077467500159989 615.1375762418598 424386.25416938204 0.019196076643926 0.0399347038181257 3.2609638275739812e-06 5.486654018603471 -0.13277512177604467 ELSNS(ph)PLRENSFGSPLEFR ddPTM_PC-9_Lapatinib_30min_R1 5 ELSNSPLRENSFGSPLEFR 19 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 ELS(0.057)NS(0.94)PLRENSFGS(0.002)PLEFR;ELS(0.053)NS(0.947)PLRENS(0.001)FGSPLEFR;ELS(0.028)NS(0.932)PLRENS(0.039)FGS(0.001)PLEFR;ELS(0.001)NS(0.561)PLRENS(0.364)FGS(0.074)PLEFR;ELS(0.034)NS(0.958)PLRENS(0.001)FGS(0.007)PLEFR 105.92 0.0011158 760623000.0 249132.0 183757.0 236862.0 184128.0 213830.0 203223.0 161511.0 154403.0 223298.0 151899.0 True False 245579.33199478668 183331.52195649664 217388.12067376115 197669.38735300142 201252.93980595478 194531.626025951 169873.24930060774 161577.1270558638 198147.8278078162 178154.53975730497 1.3784623862481005 1.0290589406604183 1.2202221788448557 1.109538873509937 1.1296537269278466 1.0919262921447643 0.9535162535404452 0.9069492547087258 1.1122244096487663 1.0 17.44276972132033 -1.5228787452803867 0.2766317062915437 0.9791316212269461 3.2631894508217867 0.5076034306528188 0.09053682877136203 44.570681308743275 0.626452923393552 0.10217892992099227 49.00313589484204 0.029999999999996606 1.5228787452803867 2.2840578295948406 ELSNSPLRENS(ph)FGSPLEFR ddPTM_PC-9_AZD4547_30min_R2 2 ELSNSPLRENSFGSPLEFR 19 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 ELS(0.007)NS(0.255)PLRENS(0.434)FGS(0.303)PLEFR;ELS(0.001)NS(0.034)PLRENS(0.95)FGS(0.015)PLEFR 98.337 0.002693 249510000.0 20185.9 13442.6 26295.0 32256.0 28399.0 20674.0 16576.0 30485.0 18141.9 25560.0 True False 26604.596307196884 17787.657565629528 25946.31111915221 24819.87755023217 24456.289052422482 19381.251511792532 18051.231888033075 25774.24372560984 19100.843796577083 24665.152179858513 1.0786309410619455 0.7211655308640209 1.051942065062136 1.006273035302819 0.9915320559989658 0.7857746577221284 0.7318516324733506 1.0449659315970896 0.774406079366288 1.0 14.590186568096122 -6.743866077328487 24.998804760869927 0.8617382623754176 0.9626673184235235 0.13513090405670358 0.12862033803589035 525.8659828404001 748066.4525816528 0.041722665038864556 0.04163296251234869 1.803573820194226e-07 6.743866077328487 0.10092905604810587 ELSNSPLRENSFGS(ph)PLEFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELSNSPLRENSFGSPLEFR 19 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 ELS(0.024)NS(0.176)PLRENS(0.121)FGS(0.679)PLEFR;ELS(0.018)NS(0.163)PLRENS(0.285)FGS(0.534)PLEFR 62.998999999999995 0.0065969999999999996 374813000.0 46821.0 40289.0 57570.0 59090.0 61127.0 69077.0 53422.0 60526.0 56312.0 42915.0 True False 54746.87054309732 44288.625659274985 58942.68713544081 55779.37887236476 49149.603153841075 65454.480516891395 48361.48141821345 58937.25663259799 57135.456468162556 50695.14978504693 1.0799232426618746 0.8736264878802742 1.1626888841509366 1.1002902468752045 0.969512928993027 1.2911389116005312 0.9539666343480886 1.1625817633935103 1.1270398984996246 1.0 15.6295601047705 -5.273134970730881 24.982332316465477 1.0992552947660554 0.9767748552875604 0.1647029594176097 0.1070976739994874 1056.0005564297483 2255668.3832457173 0.026177947373314723 0.05522398365870853 5.331691705727032e-06 5.273134970730881 -0.12248043947849507 ELSPLISLPS(ph)PVPPLS(ph)PIHSNQQTLPR ddPTM_PC-9_AZD4547_30min_R2 1 ELSPLISLPSPVPPLSPIHSNQQTLPR 27 0 A0A669KBI3;F5GXF9;P51825;P51825-3;P51825-2;E7ETI4;E7EMC5 A0A669KBI3 AFF1 AF4/FMR2 family member 1 2 ELS(0.003)PLIS(0.045)LPS(0.952)PVPPLS(0.813)PIHS(0.155)NQQT(0.032)LPR 94.045 7.5668e-09 2729100.0 3902.6 3522.9 7157.5 8059.1 5331.5 9398.3 5802.8 6826.9 5802.4 6862.4 True False 5143.545620877271 4661.6085309356995 7062.5868733725765 6201.199006853802 4591.313253388866 8810.62281528875 6319.237958486861 5771.959471555381 6109.103018165624 6622.1494647519985 0.7767184428945683 0.7039419082502207 1.0665097353910409 0.936432957283914 0.6933267329327505 1.3304777945870043 0.9542578270276959 0.8716141944965211 0.922525692100852 1.0 12.69308385800996 -5.251690289395739 24.796982229520975 0.9682694401979547 0.7403301468469653 0.2691002828772925 0.15255792742841606 829.884858302512 2110814.2999434825 0.039167072038648616 0.10086882179898436 5.601569266131742e-06 5.251690289395739 -0.2279392933509894 ELSPLISLPS(ph)PVPPLS(ph)PIHSNQQTLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELSPLISLPSPVPPLSPIHSNQQTLPR 27 0 A0A669KBI3;F5GXF9;P51825;P51825-3;P51825-2;E7ETI4;E7EMC5 A0A669KBI3 AFF1 AF4/FMR2 family member 1 2 ELS(0.013)PLIS(0.053)LPS(0.935)PVPPLS(0.925)PIHS(0.059)NQQT(0.017)LPR 74.494 0.00012984 1685300.0 2059.6 3023.6 3149.2 5385.0 4658.6 6319.2 5810.9 5323.2 3289.5 2761.6 True False 2408.2496010457526 3323.7630257237392 3224.2888714075057 5083.295908405553 3745.780772039917 5987.810027684178 5260.4494847272 5183.471640396616 3337.602714377407 3262.2562191864267 0.738215958293535 1.0188540698230784 0.9883616291217034 1.558214795793469 1.1482178346414729 1.835481220778384 1.6125188002673505 1.5889222955299693 1.0230964369836564 1.0 11.67165438113039 -5.679603086903949 5.294395863099405 1.4364032989245559 0.9102568020616552 0.3987672238205615 0.2677303570248438 0.19299336906982004 9.15441511890682 0.07271104510678304 0.12718707364603368 2.091206466101726e-06 5.679603086903949 -0.5261464968629007 ELSPLISLPSPVPPLS(ph)PIHSNQQTLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELSPLISLPSPVPPLSPIHSNQQTLPR 27 0 A0A669KBI3;F5GXF9;P51825;P51825-3;P51825-2;E7ETI4;E7EMC5 A0A669KBI3 AFF1 AF4/FMR2 family member 1 1 ELSPLISLPS(0.035)PVPPLS(0.953)PIHS(0.008)NQQT(0.003)LPR 75.10600000000001 3.0891e-05 1827300.0 3703.7 1708.2 4038.8 5194.1 4639.1 3129.7 4047.9 4268.3 4119.6 3947.5 True False 4330.663258590576 1877.7788068994876 4135.100309234294 4903.091416499404 3730.1016570579973 2965.57302247803 3664.453607741874 4156.261647637678 4179.841356482496 4663.150501607193 0.9286990109150407 0.40268458121870515 0.8867610658950634 1.0514546795797204 0.7999102014340705 0.6359591056424022 0.785832154994545 0.8912990576232074 0.8963556623449916 1.0 12.187089277586397 -14.522878676229178 0.08507198829905546 1.6882017514230934 0.6149450236146218 0.1289877727996246 0.16750455451607477 496.44053040139147 2.9515813962389945 61.983400773249166 4.972531931795309 3.0000004769885505e-15 14.522878676229178 -1.0732567278084715 ELSS(ph)PISPK ddPTM_PC-9_Lapatinib_30min_R1 1 ELSSPISPK 9 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 ELS(0.008)S(0.747)PIS(0.244)PK 104.42 0.0039589 0.0 46034.0 48726.0 46376.0 41395.0 33686.0 40086.0 33444.0 37708.0 35502.0 28254.0 True False 45377.546718398335 48613.17794071651 42563.14429653695 44439.32638967194 31704.65570922415 38371.61522503001 35175.56667725122 39460.051339821875 31503.390907366364 33137.66625391148 1.3693645886436585 1.4670066856315913 1.2844339722177303 1.341051782257794 0.9567558399041399 1.1579456118307887 1.0614980067613904 1.1907915010509866 0.9506822437638557 1.0 15.016184382758677 -6.180998046774817 6.256794732986931 1.0685769864859136 1.3702612386563195 0.7656357827963933 0.08447773866701438 0.11663831859945256 7.379332728230808 0.024392479173918038 0.03160831830451456 6.591768598639546e-07 6.180998046774817 0.30168425217040595 ELSSEPQT(ph)PPAQK ddPTM_PC-9_AZD4547_30min_R2 2 ELSSEPQTPPAQK 13 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 ELSSEPQT(1)PPAQK;ELSSEPQT(1)PPAQK 173.25 0.00023275 11768900.0 81247.0 77109.0 103656.0 129371.0 119889.0 104663.0 84839.0 102751.0 77164.0 88455.0 True False 107081.85595741722 102032.97630132016 102281.45371237284 99546.5147120254 103244.48178477708 98118.40606456123 92389.50664507969 86873.19393308637 81242.73150657189 85358.21737360641 1.2544996750427448 1.1953503650940787 1.1982613608798167 1.1662206378598312 1.2095435561040813 1.1494898685044517 1.0823739001096737 1.017748455931888 0.9517857097574876 1.0 16.381242426692197 -7.457442432641695 1.264720309393865 0.9730558839761332 1.2044513765122278 0.9370389657921696 0.024510695560783304 0.10454248567218792 0.31734220644956557 0.0175542974284156 0.008564130340759606 3.487848138030929e-08 7.457442432641695 0.2313954925360946 ELSSEPQT(ph)PPAQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELSSEPQTPPAQK 13 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 ELSSEPQT(1)PPAQK;ELSSEPQT(1)PPAQK 145.81 1.1094000000000001e-07 4038400.0 39053.0 30741.0 34159.0 47391.0 73207.0 64508.0 71497.0 73503.0 62466.0 57135.0 True False 45663.901568090776 33792.76331980867 34973.4801087289 44735.83591369499 58862.61387084665 61125.08692015619 64724.286566545794 71573.62413286605 63379.44707593838 67493.12321958879 0.6765711733256636 0.5006845395176626 0.5181784223400469 0.6628206516410124 0.8721275748247301 0.9056491091882917 0.9589760182821206 1.0604580247383333 0.9390504402905379 1.0 16.042452895010655 -6.320449937999331 1.5991057479772237 0.9836078481803581 0.5539556956746418 0.9113088039342248 0.05736111630925547 0.10218811680151059 0.5202266866902132 0.02166945915231918 0.027958689412493704 4.781344784980805e-07 6.320449937999331 -0.4296521525057163 ELSSEPQT(ph)PPAQK ddPTM_PC-9_Lapatinib_30min_R1 2 ELSSEPQTPPAQK 13 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 ELSSEPQT(1)PPAQK;ELS(0.001)S(0.02)EPQT(0.979)PPAQK 131.32 0.00035704 3841500.0 51543.0 51188.0 53281.0 48730.0 81696.0 101182.0 87815.0 88550.0 95462.0 80764.0 True False 50807.98736817142 51069.47733098136 48900.441850607735 52313.766758514634 76890.80190051584 96854.68172676212 92361.63101790495 92664.35626766788 84710.06430057481 94723.94978873435 0.536379526840783 0.5391400743411053 0.5162415836720475 0.5522760281342954 0.8117355966680834 1.0224941204709053 0.9750610191393185 0.9782568872427719 0.8942834889117927 1.0 16.531441619108094 -6.401538674605439 2.674315119904651 0.9720305599709367 0.5298486165746223 0.9737572262108477 0.03387813355728248 0.04100442403461118 0.57014476945942 0.011650589499521273 0.013406494717327574 3.966992006720377e-07 6.401538674605439 -0.44218194339631434 ELSSPIS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 ELSSPISPK 9 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 ELSSPIS(1)PK;ELSS(0.001)PIS(0.999)PK 99.568 0.0065806 0.0 57968.0 54793.0 59341.0 61960.0 54347.0 57277.0 58201.0 64309.0 61262.0 52550.0 True False 76400.618190697 72503.76571448529 58554.09956727941 47676.07927245739 46801.85714750537 53695.46013548132 63380.77624972324 54371.521723806545 64500.1842511482 50710.24049497513 1.5066112375914984 1.4297657634195142 1.1546799817106277 0.9401666962550022 0.9229271383980708 1.058868181483028 1.2498614802665673 1.0722000367794393 1.2719360748750446 1.0 15.629989495998668 -5.272691001854744 3.2136545675995363 1.0754701073396082 1.4891429887855518 0.6733722412662403 0.10867894683760479 0.15018369468250475 3.192523245293929 0.03142655974399053 0.08794750810649186 5.33714495370306e-06 5.272691001854744 0.4136728814459436 ELSSPIS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELSSPISPK 9 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 ELS(0.005)S(0.027)PIS(0.968)PK 76.143 0.024945 3730000.0 30966.0 26253.0 25052.0 39855.0 36098.0 32173.0 39450.0 30061.0 27762.0 22350.0 True False 36207.93219362147 28859.224339967357 25649.334690239084 37622.05356165335 29024.85603166122 30485.791242670446 35713.010406733585 29271.930602262313 28167.96672945604 26401.87807749733 1.3714150215882546 1.0930746765535766 0.9714965963766172 1.4249764146028356 1.0993481579781814 1.1546826764817875 1.3526693177623699 1.1087063774910455 1.066892538734355 1.0 14.68835293779684 -7.991775503778751 24.902576562230752 1.0515639465348696 1.2002836787694557 0.21710986531215215 0.13490466312133817 288.64760926470325 873983.0992828421 0.0734535137993769 0.03518965742348562 1.0191180561089669e-08 7.991775503778751 0.14871973223458612 ELST(ph)SPCNPIVR ddPTM_PC-9_AZD4547_30min_R2 1 ELSTSPCNPIVR 12 0 H3BSS6;Q9H2Y7;H3BNX5 H3BSS6 ZNF106 Zinc finger protein 106 1 ELS(0.001)T(0.5)S(0.5)PCNPIVR 194.06 4.1200000000000005e-05 44730000.0 25053.0 26550.0 36584.0 56422.0 45138.0 38673.0 36091.0 50847.0 32054.0 37493.0 True False 33019.33286522788 35131.768286452316 36098.872256439055 43414.7796112103 38871.367838594495 36254.77119645703 39303.02908246871 42989.7644978213 33748.30900046205 36180.381481981036 0.9126308654780918 0.9710170774166391 0.9977471430039351 1.1999536166536062 1.0743769481245977 1.0020560787760915 1.0863077577565856 1.1882065013391732 0.9327792471527634 1.0 15.142919999207352 -5.5326176518603924 24.9085242577181 1.0769111059083585 0.9524634755854797 0.2976820220720907 0.07864114857541765 216.09624340924734 552692.6452228286 0.020919978776889295 0.03629151140608167 2.9334747079737666e-06 5.5326176518603924 -0.12444763032287876 ELST(ph)SPCNPIVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ELSTSPCNPIVR 12 0 H3BSS6;Q9H2Y7;H3BNX5 H3BSS6 ZNF106 Zinc finger protein 106 1 ELS(0.104)T(0.705)S(0.191)PCNPIVR;ELS(0.001)T(0.943)S(0.056)PCNPIVR;ELS(0.003)T(0.499)S(0.499)PCNPIVR 225.33 5.5984e-15 58032700.0 203195.0 228341.0 295520.0 310176.0 301668.0 264430.0 276765.0 281880.0 250543.0 203813.0 True False 237591.9002158152 251009.18542690304 302566.3175658407 292797.84432416066 242558.32094185756 250562.82529758968 250547.81559492068 274480.9486765475 254206.71739421118 240762.68351717968 0.986830254360667 1.0425585134707647 1.2566993902285983 1.216126353331944 1.0074581218253855 1.0407045711455143 1.040642228832122 1.140047721128519 1.0558393588268515 1.0 17.87725227651527 -6.282608044483533 24.942046633977156 1.0537735304060856 1.1289929793178721 0.1822367667347351 0.08025569127267673 1581.5465504184954 1863457.1371136624 0.027272660631224174 0.030951539365427175 5.216653073553505e-07 6.282608044483533 0.07521944891178656 ELSTTLNADEAVTR ddPTM_PC-9_Lapatinib_30min_R1 2 ELSTTLNADEAVTR 14 0 A0A087WYC1;P34932;A0A087WTS8 A0A087WYC1 HSPA4 Heat shock 70 kDa protein 4 0 ; 115.12 0.00075421 7109000.0 15697.400000000001 13506.4 18069.7 15237.0 14410.4 14642.0 14445.8 14203.0 18621.0 11377.8 False True 15473.552197449397 13475.126760630748 16584.07901705911 16357.579809141955 13562.808603936455 14015.795792169069 15193.732840157736 14862.923230600676 16523.706892177048 13344.437570034468 1.1595507203837463 1.0097935330665226 1.2427709245910372 1.2257976196669114 1.0163641991470924 1.0503099676259242 1.1385817319327076 1.113791656830561 1.238246783010306 1.0 13.703950880831405 -6.254323072193981 24.97290100126579 1.098728318375769 1.1547359099483856 0.12271076333854314 0.08601597360510732 1537.9568111322558 5397069.508623894 0.026554212699560348 0.033615466831229165 5.56771411906763e-07 6.254323072193981 0.05600759157261659 ELSVQDQPSLSPT(ph)SLQNSSSHTTTAK ddPTM_PC-9_AZD4547_30min_R2 3 ELSVQDQPSLSPTSLQNSSSHTTTAK 26 0 O95628-3;O95628-2;O95628;O95628-8;O95628-4;O95628-7;O95628-9;O95628-10;O95628-6 O95628-3 CNOT4 CCR4-NOT transcription complex subunit 4 1 ELSVQDQPS(0.002)LS(0.107)PT(0.89)S(0.001)LQNSSSHTTTAK;ELSVQDQPS(0.001)LS(0.087)PT(0.728)S(0.184)LQNSSSHTTTAK;ELSVQDQPS(0.007)LS(0.025)PT(0.967)S(0.001)LQNSSSHTTTAK 174.19 4.0971e-17 63431000.0 6652.6 16505.2 167097.0 442542.0 253124.0 187375.0 75368.9 293011.0 106349.0 175879.0 True False 8767.988417323872 21840.183123222323 164881.1846007598 340520.77910574345 217982.10183828213 175658.41162920228 82076.5860910941 247732.88267294338 111970.39102421346 169721.52974340157 0.051661026332840684 0.1286824550558909 0.9714806651226878 2.0063499287366175 1.2843515031230552 1.0349801341926188 0.48359560637465365 1.459643234700309 0.6597300365693095 1.0 17.37281006161478 -5.288258901350501 4.435132529909664 1.1495555765700294 0.07144369792281575 0.5168117241488775 0.3970910003492414 0.15188050608743547 7.4442878735529465 0.10937082203451774 0.2618028273292425 5.14921586480335e-06 5.288258901350501 -1.0781118786472137 ELTAVVQK ddPTM_PC-9_Lapatinib_30min_R1 1 ELTAVVQK 8 0 P23396;P23396-2;E9PL09;F2Z2S8;H0YCJ7;E9PPU1;H0YF32;E9PQ96;E9PJH4;E9PK82 P23396 RPS3 40S ribosomal protein S3 0 116.37 0.016555 7271100.0 106310.0 79891.0 87492.0 79896.0 86769.0 71177.0 75337.0 60945.0 63191.0 66461.0 False True 104793.99990513369 79706.01729798825 80298.74548888687 85771.81836524296 81665.41801441756 68132.92563169097 79237.58123322795 63776.727190661004 56073.764149270115 77948.69529628404 1.3443971000003307 1.022544598020847 1.030148678995463 1.1003624632743771 1.0476816539905665 0.8740739709974208 1.016535054654152 0.8181885142303511 0.7193675780734107 1.0 16.250237254873618 -1.5228787452803574 0.30892818826726404 0.859750399890446 4.592490833007355 0.5840144231736301 0.10404662149239848 41.38212357381924 0.5907781039038993 0.10534755914496904 86.22429788974641 0.029999999999998632 1.5228787452803574 3.732740433116909 ELTDEEAER ddPTM_PC-9_AZD4547_30min_R2 2 ELTDEEAER 9 0 Q9Y266;A0A0A0MSS4;A0A0A0MSU9 Q9Y266 NUDC Nuclear migration protein nudC 0 ; 126.24 0.006453699999999999 29573000.0 79792.0 82154.0 132669.0 136730.0 102176.0 127834.0 84925.0 121848.0 106992.0 103091.0 False True 105164.19622329703 108708.67389096812 130909.72237561534 105209.010957442 87990.6260861409 119840.51977162082 92483.16047847537 103019.19138848946 112647.37869150282 99481.81546845826 1.0571197934826635 1.0927491962130036 1.315916097421057 1.057570275150433 0.884489548886844 1.2046474946933141 0.9296489015904431 1.035558015335504 1.132341404919564 1.0 16.602145215446072 -5.977651280841328 24.97787997172057 1.0305440661695981 1.1552992709265337 0.21616661387733305 0.10606320026782709 349.89289502179577 391052.2759280245 0.029341593828586806 0.043516861156581835 1.0528068916443587e-06 5.977651280841328 0.12475520475693558 ELTDEEAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELTDEEAER 9 0 Q9Y266;A0A0A0MSS4;A0A0A0MSU9 Q9Y266 NUDC Nuclear migration protein nudC 0 96.66799999999999 0.023178999999999998 15062000.0 29266.0 29747.0 42964.0 32393.0 39249.0 26018.0 35638.0 34773.0 34754.0 26173.0 False True 34220.15577015199 32700.08556892583 43988.42470187737 30578.125229522968 31558.44020130397 24653.570277928684 32262.110643223594 33860.24559503899 35262.2115018916 30917.95771464601 1.1068051805356378 1.0576405424552222 1.4227467773862632 0.9890085726793636 1.020715549602895 0.7973867648525229 1.0434748291262734 1.0951643671793756 1.140509079782708 1.0 14.916157404754571 ELTDEEAER ddPTM_PC-9_Lapatinib_30min_R1 1 ELTDEEAER 9 0 Q9Y266;A0A0A0MSS4;A0A0A0MSU9 Q9Y266 NUDC Nuclear migration protein nudC 0 114.89 0.0092684 15584000.0 16640.0 27092.0 27870.0 22610.0 30276.0 26446.0 17702.0 22126.0 22304.0 20414.0 False True 16402.710548597726 27029.270138527514 25578.63618131111 24272.814824748944 28495.225204906183 25314.966228637044 18618.522943448774 23154.054734934194 19791.888648467677 23942.532700054824 0.6850866929612742 1.12892276172878 1.068334603600752 1.0137947864092658 1.1901508316553717 1.0573219861814818 0.7776338107875338 0.9670678964920523 0.826641395729298 1.0 14.54728815173656 -7.235319577188403 24.612606921048066 0.8900914184421318 1.0378199230862533 0.1722703891750934 0.1387413973521623 979.6662101881124 923137.4374563588 0.051787127311159635 0.040099911758609566 5.816750325418675e-08 7.235319577188403 0.14772850464412146 ELTHIYR ddPTM_PC-9_AZD4547_30min_R2 2 ELTHIYR 7 0 P22059 P22059 OSBP Oxysterol-binding protein 1 0 ; 102.72 0.0090534 3857500.0 18632.4 17548.0 20880.2 32884.0 25998.0 21145.5 22295.0 25956.0 18622.5 21666.8 False True 24557.11562200421 23220.047830156884 20603.314905119674 25303.101852735457 22388.626458145696 19823.26854225641 24279.21180886205 21945.09660954333 19606.847331412755 20908.251926860652 1.1745178749475413 1.110568588487605 0.98541547027424 1.2101969089165594 1.0708033620631487 0.9481074080989825 1.1612262896866454 1.0495902137734743 0.9377564131138102 1.0 14.351784827327162 -1.5228787452803376 0.14040951468203874 0.9648966421826815 1.5922451624887697 0.25131501164853487 0.07981889546136617 119.87513969140996 1.1246256484861898 0.34776330531759203 15.09556096219849 0.029999999999999995 1.5228787452803376 0.6273485203060882 ELTHIYR ddPTM_PC-9_Lapatinib_30min_R1 2 ELTHIYR 7 0 P22059 P22059 OSBP Oxysterol-binding protein 1 0 ; 107.32 0.0018756 1505300.0 36212.0 29105.0 32156.0 27736.0 28410.0 29210.0 29397.0 27385.0 29321.0 22899.0 False True 35695.61023953249 29037.609160705855 29512.257805749563 29775.79796458366 26738.97965620903 27960.75639183573 30919.032819374283 28657.407073857597 26018.560216181882 26857.06163900047 1.3290958899128835 1.0811908447400256 1.0988639860323868 1.1086766811952633 0.9956033171320586 1.041095141667789 1.1512440651539937 1.0670343412491097 0.9687791079273931 1.0 14.713013851450636 -2.218165047044931 1.2420122985329995 1.054979474400883 199.99999962636787 0.6985257402210532 0.0537148252707077 615.9462168641825 1.7446304830569286 0.016019777701199743 348211.48380539735 0.006051108678242099 2.218165047044931 198.945020151967 ELTIGSK ddPTM_PC-9_AZD4547_30min_R2 1 ELTIGSK 7 0 R4GN98;P06703 R4GN98 S100A6 Protein S100;Protein S100-A6 0 109.01 0.044578 9175400.0 47211.0 39425.0 47838.0 58505.0 56776.0 53395.0 45843.0 49837.0 38450.0 52054.0 False True 62223.115950196465 52168.36025210479 47203.63686320609 45017.576143239494 48893.632425097305 50056.20220915938 49922.93819034145 42135.83679033023 40482.38850276926 50231.60530400449 1.2387244161045357 1.0385565011585622 0.939719855209226 0.896200228338127 0.9733639235535138 0.9965081128945897 0.9938551214560041 0.8388311807938803 0.8059146877303158 1.0 15.616307761011893 -4.763179647936725 1.8344791727439944 0.9286315242748162 1.3499759760065586 0.6889394438545804 0.06347852438451085 0.5538635978911546 1.867950277664804 0.01883022361010017 0.41415726449274076 1.7251241387357546e-05 4.763179647936725 0.4213444517317424 ELTIGSK ddPTM_PC-9_Lapatinib_30min_R1 2 ELTIGSK 7 0 R4GN98;P06703 R4GN98 S100A6 Protein S100;Protein S100-A6 0 ; 122.13 0.024516 120824000.0 269274.0 293597.0 290891.0 297830.0 281895.0 284665.0 313086.0 259477.0 254728.0 272359.0 False True 265434.1033811966 292917.1941850462 266975.06485173194 319733.4117317544 265314.4903268937 272490.5415365257 329296.06113843695 271533.24868736044 226037.8502352435 319435.8902544441 0.830946401075243 0.9169827283707079 0.8357704096401788 1.0009313965223923 0.830571950182428 0.8530367120597362 1.0308674484765592 0.8500398889776375 0.7076156973319274 1.0 18.28516689045206 -7.984923591211978 24.975696634163157 0.8288144185803502 0.9005543406538322 0.03802327705958242 0.09355119861874076 509.05719548740905 843307.9054465155 0.048478973165552636 0.023275686729561436 1.0353243032707497e-08 7.984923591211978 0.07173992207348201 ELTPAS(ph)PTCTNSVSK ddPTM_PC-9_AZD4547_30min_R2 4 ELTPASPTCTNSVSK 15 0 A0A494C0S2;A0A090HNM7;A0A1W2PS85;R4GMW8;P28715 A0A494C0S2 ERCC5-201;BIVM-ERCC5;ERCC5 DNA repair protein complementing XP-G cells 1 ELT(0.112)PAS(0.885)PT(0.002)CT(0.001)NSVSK;ELT(0.082)PAS(0.871)PT(0.045)CT(0.002)NSVSK;ELTPAS(1)PTCTNSVSK;ELTPAS(0.876)PT(0.116)CT(0.007)NS(0.001)VSK 304.03 7.585399999999999e-121 131729000.0 154038.0 177014.0 210573.0 237558.0 207823.0 233771.0 200380.0 235481.0 187941.0 197076.0 True False 203018.87981056055 234230.31380256396 207780.6644340461 182792.67333451312 178970.36373610282 219153.26241478385 218213.43181250434 199092.82226505922 197875.17757084404 190176.42922526575 1.0675291393240054 1.2316474484075837 1.0925679132818715 0.9611741795719253 0.941075423832418 1.1523681631186522 1.147426275177501 1.0468848483280329 1.04048213743912 1.0 17.53697892175476 -5.518228608180737 24.965829147388106 1.046528070050346 1.1527181514890832 0.25192638321086025 0.07448265832612615 268.2343594607576 1440101.9480853777 0.02144755922191654 0.0384578659086264 3.0322945951046316e-06 5.518228608180737 0.1061900814387371 ELTPAS(ph)PTCTNSVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELTPASPTCTNSVSK 15 0 A0A494C0S2;A0A090HNM7;A0A1W2PS85;R4GMW8;P28715 A0A494C0S2 ERCC5-201;BIVM-ERCC5;ERCC5 DNA repair protein complementing XP-G cells 1 ELT(0.148)PAS(0.699)PT(0.143)CT(0.01)NS(0.001)VSK;ELT(0.001)PAS(0.914)PT(0.083)CT(0.002)NSVSK 252.1 2.7052999999999994e-41 47717000.0 120977.0 133876.0 137155.0 140892.0 165198.0 125631.0 145925.0 103884.0 115442.0 113196.0 True False 141456.01669533487 147166.32452433932 140425.295363234 132998.2780180272 132828.6377837653 119042.6891992642 132101.9275944889 101157.15507419633 117130.1208551931 133717.53874095678 1.0578718246479948 1.100576079323716 1.0501636261438507 0.9946210442571564 0.9933523981553871 0.8902548634990859 0.9879177319469086 0.7564987811371716 0.8759518157307882 1.0 17.028829179921345 -6.370218478430885 0.9032169352962945 0.8794912562683266 1.0828861829644236 0.5398905826338241 0.06588806430580306 0.4163932352652805 0.7356934295395653 0.03355768317730858 0.047909312694286915 4.263649754691593e-07 6.370218478430885 0.20339492669609704 ELTPAS(ph)PTCTNSVSK ddPTM_PC-9_Lapatinib_30min_R1 3 ELTPASPTCTNSVSK 15 0 A0A494C0S2;A0A090HNM7;A0A1W2PS85;R4GMW8;P28715 A0A494C0S2 ERCC5-201;BIVM-ERCC5;ERCC5 DNA repair protein complementing XP-G cells 1 ELT(0.18)PAS(0.675)PT(0.115)CT(0.028)NS(0.002)VSK;ELTPAS(0.982)PT(0.017)CT(0.001)NSVSK;ELT(0.01)PAS(0.813)PT(0.066)CT(0.101)NS(0.009)VSK 249.54 1.6618e-40 98337000.0 202928.0 231894.0 241826.0 202709.0 224023.0 235765.0 226676.0 249984.0 243391.0 179772.0 True False 200034.20950756254 231357.06369052487 221943.9997553549 217616.89607740103 210846.40758616416 225681.88054505832 238412.17414581362 261599.16925145968 215977.74255914608 210845.35066886764 0.9487247827518663 1.0972832123477594 1.0526388134776454 1.0321161713409943 1.0000050127607423 1.0703668818360212 1.130744279584517 1.2407158536889005 1.0243419732709158 1.0 17.68582568367102 -7.0388801072508596 4.372037453280859 1.1179395167190382 1.0318694125744015 0.1682009733885964 0.07114087111253002 0.3121199399051119 13.362375031005334 0.026655367149699304 0.021223196113024905 9.143656293848042e-08 7.0388801072508596 -0.08607010414463678 ELTPASPT(ph)CTNSVSK ddPTM_PC-9_Lapatinib_30min_R1 1 ELTPASPTCTNSVSK 15 0 A0A494C0S2;A0A090HNM7;A0A1W2PS85;R4GMW8;P28715 A0A494C0S2 ERCC5-201;BIVM-ERCC5;ERCC5 DNA repair protein complementing XP-G cells 1 ELTPAS(0.199)PT(0.658)CT(0.131)NS(0.012)VSK 144.4 0.00025857 34502000.0 46483.0 52567.0 48848.0 55090.0 58595.0 60709.0 54903.0 59940.0 59411.0 44268.0 True False 45820.143896061774 52445.284341206854 44831.905998732866 59141.50237485266 55148.55730220237 58112.61758959105 57745.60869755782 62725.03122172813 52719.507554434764 51919.66481659779 0.8825200250794741 1.0101237079720329 0.8634860443937401 1.139096382531849 1.0621901643049967 1.119279521446631 1.1122107375218953 1.2081170293240426 1.0154053910144134 1.0 15.663993449153969 -5.767087199393984 24.999697607187457 1.102945643052397 0.927851295651325 0.5820061607347649 0.06753461367058662 87.3636100545598 386711.3734649809 0.0178206985386002 0.027276661531493895 1.709672005799679e-06 5.767087199393984 -0.175094347401072 ELTPASPTCT(ph)NSVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELTPASPTCTNSVSK 15 0 A0A494C0S2;A0A090HNM7;A0A1W2PS85;R4GMW8;P28715 A0A494C0S2 ERCC5-201;BIVM-ERCC5;ERCC5 DNA repair protein complementing XP-G cells 1 ELT(0.047)PAS(0.049)PT(0.041)CT(0.704)NS(0.159)VS(0.001)K;ELT(0.006)PAS(0.325)PT(0.049)CT(0.475)NS(0.146)VSK 114.89 0.00041209 52971000.0 43793.0 46203.0 55950.0 49602.0 55443.0 47519.0 54738.0 33225.0 44736.0 40168.0 True False 51206.28994882337 50789.7284950106 57284.06019155659 46822.96075185371 44579.342150905635 45027.019987581414 49552.820371198555 32352.87895479741 45390.17936780292 47450.14043028696 1.0791599241746161 1.0703809943329905 1.2072474321907958 0.986782343050076 0.9394986347069075 0.9489333346385863 1.0443134608632154 0.6818289400498145 0.9565868289576401 1.0 15.534124736506662 -5.9544327229140555 5.33231347900376 0.9226439626105495 1.113861457932435 0.4367168604924757 0.09639703740301177 0.17995508850981815 11.853669230787022 0.027982085713170728 0.04156963210261687 1.110624570210028e-06 5.9544327229140555 0.1912174953218856 ELTTS(ph)SPEGCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ELTTSSPEGCR 11 0 F2Z3D5;Q15306-2;Q15306 F2Z3D5 IRF4 Interferon regulatory factor 4 1 ELT(0.191)T(0.191)S(0.612)S(0.006)PEGCR 67.214 0.040263 11697000.0 2404.5 0.0 0.0 0.0 0.0 3415.2 2839.1 0.0 0.0 0.0 True False 2811.53435896024 0.0 0.0 0.0 0.0 3236.100899884006 2570.1598946960016 0.0 0.0 0.0 0.0 ELVEFAQDDDRLR ddPTM_PC-9_AZD4547_30min_R2 2 ELVEFAQDDDRLR 13 1 Q14677-2;Q14677;Q14677-3 Q14677-2 CLINT1 Clathrin interactor 1 0 ; 123.26 0.00021945 8283200.0 20740.0 18718.1 26244.0 28720.0 27648.0 27385.0 23444.0 25698.0 24902.4 24094.0 False True 27334.888581200878 24768.359772604254 25895.987412475006 22099.04771957676 23809.55243921886 25672.61162089766 25530.47058295411 21726.964581293134 26218.69002474281 23250.476393642843 1.1756700429877986 1.0652839689502633 1.113783088743743 0.950477200786264 1.0240457888307561 1.104175724671047 1.098062256906472 0.9344739528534448 1.1276624866022762 1.0 14.504972656359573 -4.190080333764698 1.167656001619788 1.0401614689675336 1.5007285155299137 0.2788175746372592 0.064069607783238 7.18112695421964 3.1372017445714686 0.018988967068714762 5.648705115734457 6.455348099763131e-05 4.190080333764698 0.4605670465623801 ELVEFAQDDDRLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ELVEFAQDDDRLR 13 1 Q14677-2;Q14677;Q14677-3 Q14677-2 CLINT1 Clathrin interactor 1 0 ; 117.03 0.00034344 4964700.0 17421.2 19864.6 21195.0 24858.0 23836.5 24426.0 23368.0 18640.300000000003 20523.4 15602.1 False True 20370.2650756158 21836.626207432124 21700.369182485116 23465.286850723372 19165.908936746982 23145.057560484518 21154.413870330816 18151.011876030414 20823.51589854183 18430.637223844355 1.105239326682752 1.1848003919897747 1.1774074286704854 1.273167420406144 1.0398939930276194 1.2557925848890865 1.1477852671834166 0.9848282322299644 1.1298315758503308 1.0 14.169818331353 -7.628394399195694 6.383488014573286 1.0441153149832496 1.1743123727007665 0.41011721525028555 0.07229131175369855 0.20620352800731964 10.970782870739265 0.03269480842648739 0.01863270846889399 2.352911545662738e-08 7.628394399195694 0.13019705771751688 ELVEFAQDDDRLR ddPTM_PC-9_Lapatinib_30min_R1 2 ELVEFAQDDDRLR 13 1 Q14677-2;Q14677;Q14677-3 Q14677-2 CLINT1 Clathrin interactor 1 0 ; 169.09 0.00016140000000000002 9791800.0 21162.5 24594.0 28393.0 20773.9 23140.0 26755.0 23985.0 24354.0 22631.0 19850.8 False True 20860.718869272812 24537.05410405086 26058.637140149505 22301.681905698908 21778.950694990413 25610.751018951214 25226.82594049367 25485.575748648105 20082.05846500502 23281.984330471652 0.8960026161502966 1.053907336924738 1.119261862316596 0.9578943782944774 0.9354422022561859 1.1000244075171743 1.0835341860219616 1.094647921195118 0.8625578550330633 1.0 14.506926404364783 -4.754697433439472 24.9916742064865 1.0285192334925048 0.8960023902588218 0.18353014108321808 0.07962358535629907 399.87420253302815 1482157.4513372292 0.019982165531564608 0.19015837729741597 1.7591487601356045e-05 4.754697433439472 -0.13251684323368307 ELVEPLT(ph)PSGEAPNQALLR ddPTM_PC-9_AZD4547_30min_R2 7 ELVEPLTPSGEAPNQALLR 19 0 P00533;E9PFD7;Q504U8 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 ELVEPLT(0.917)PS(0.083)GEAPNQALLR;ELVEPLT(0.994)PS(0.006)GEAPNQALLR;ELVEPLT(1)PSGEAPNQALLR;ELVEPLT(0.997)PS(0.003)GEAPNQALLR;ELVEPLT(0.996)PS(0.004)GEAPNQALLR;ELVEPLT(0.994)PS(0.006)GEAPNQALLR;ELVEPLT(0.927)PS(0.073)GEAPNQALLR 222.96 1.2219999999999998e-34 283471100.0 129259.5 233159.2 239189.1 249246.0 206781.6 148826.1 225678.9 262501.0 187099.9 150807.3 True False 170361.33223537757 308523.35172333725 236017.2962506186 191786.1855123132 178073.54415023117 139519.98044012726 245763.88490204042 221937.50212288994 196989.61874198384 145527.58232916976 1.1706463442101045 2.1200335138220487 1.6218045574121445 1.3178682861542415 1.223641190901155 0.9587184656482929 1.6887787247516113 1.525054553719501 1.3536239356770992 1.0 17.150933092300484 -5.717131329333615 4.932137281598156 1.3157749734448552 1.6949269226533474 0.2125819391916033 0.2961687902043101 0.28454920184224836 15.362113859742703 0.08157613135150882 0.14062463472120998 1.9180886287810895e-06 5.717131329333615 0.37915194920849227 ELVEPLT(ph)PSGEAPNQALLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 ELVEPLTPSGEAPNQALLR 19 0 P00533;E9PFD7;Q504U8 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 ELVEPLT(0.992)PS(0.008)GEAPNQALLR;ELVEPLT(0.998)PS(0.002)GEAPNQALLR;ELVEPLT(1)PSGEAPNQALLR;ELVEPLT(0.924)PS(0.076)GEAPNQALLR;ELVEPLT(0.896)PS(0.104)GEAPNQALLR;ELVEPLT(1)PSGEAPNQALLR;ELVEPLT(0.996)PS(0.004)GEAPNQALLR 245.74 2.6196999999999993e-53 166663400.0 140924.7 153004.7 163813.5 135733.6 371249.5 231334.0 275909.0 287135.7 266885.0 221927.9 True False 164780.46832030104 168193.99544316478 167719.43510615797 128128.88644626843 298505.8255118351 219202.43779976777 249772.90211182408 279598.6921204223 270787.68822818546 262161.67148971016 0.6285452308262715 0.6415659256649436 0.6397557436718623 0.4887399661368786 1.138632599554323 0.8361345751046276 0.9527437809368241 1.0665124712229208 1.0329034244001372 1.0 18.000097250790773 -6.259211778152546 24.999912866940267 0.9968085719502241 0.6055101550206995 0.84751387573449 0.08407275442470223 76.93645842678013 863441.557729138 0.025604125239659322 0.0314710297294348 5.505391675508385e-07 6.259211778152546 -0.3912984169295246 ELVEPLT(ph)PSGEAPNQALLR ddPTM_PC-9_Lapatinib_30min_R1 5 ELVEPLTPSGEAPNQALLR 19 0 P00533;E9PFD7;Q504U8 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 ELVEPLT(0.884)PS(0.116)GEAPNQALLR;ELVEPLT(0.973)PS(0.027)GEAPNQALLR;ELVEPLT(0.991)PS(0.009)GEAPNQALLR;ELVEPLT(1)PSGEAPNQALLR;ELVEPLT(0.998)PS(0.002)GEAPNQALLR 222.09 2.5017e-28 138459600.0 236761.0 240117.0 103677.1 78230.6 152091.5 150240.9 139830.5 124050.1 272667.0 75435.8 True False 233384.74472335004 239561.02383924412 95153.16904317938 83983.93929363115 143145.77699339384 143815.44693564376 147070.239094109 129813.92051315459 241956.3711491989 88474.7775181147 2.637867551298062 2.7076759112527338 1.0754835639309444 0.9492415991262133 1.6179275157158273 1.6254965648961184 1.6622843619357757 1.4672421243057203 2.7347496985755035 1.0 16.432978608351227 -5.247999209274774 24.509649111735413 1.5256953072481516 2.6727720388500065 0.48003579626316295 0.48126238623233786 521.2297803535232 950515.0755269644 0.12389182934512043 0.3235493564834692 5.649380034008354e-06 5.247999209274774 1.1470767316018549 ELVGPPLAET(ph)VFTPKTS(ph)PENVQDR ddPTM_PC-9_Lapatinib_30min_R1 1 ELVGPPLAETVFTPKTSPENVQDR 24 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 2 ELVGPPLAET(0.794)VFT(0.211)PKT(0.396)S(0.6)PENVQDR 76.31 0.00090979 4696800.0 17953.0 14411.0 12819.0 15696.0 10518.0 12865.0 8409.9 8655.6 12474.0 9116.9 True False 17696.986927823014 14377.632214909194 11765.071302770984 16850.33620032107 9899.351919183628 12314.793939779753 8845.323472043261 9057.770774821322 11069.046762956683 10692.744017494351 1.655046347211628 1.344615768542295 1.1002855098300495 1.5758664167731231 0.9258008891812375 1.1516963203861958 0.8272267116440333 0.8470950730702935 1.035192345841878 1.0 13.384344510664748 -5.373075885376381 0.47391404383538005 0.8995704440282265 1.7920691512176703 0.5961244993146155 0.17502853741846455 2.009716600708424 0.5239846397964633 0.12992353550300648 0.9466128923305472 4.235689483063843e-06 5.373075885376381 0.8924987071894438 ELVGPPLAETVFT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 ELVGPPLAETVFTPK 15 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 ELVGPPLAET(0.139)VFT(0.861)PK;ELVGPPLAET(0.137)VFT(0.863)PK;ELVGPPLAETVFT(1)PK;ELVGPPLAET(0.008)VFT(0.992)PK 186.85 8.533200000000001e-07 31972500.0 141163.0 170611.0 146319.0 115512.0 127062.0 179009.0 187480.0 203074.0 186766.0 154645.0 True False 186049.89762719665 225757.66927005365 144378.71445686367 88882.49304260967 109421.63454976954 167815.53893172444 204165.35680311502 171693.57947628322 196638.06946965394 149230.92562027456 1.2467248115890521 1.5128075385962905 0.9674852170001439 0.5956037106462474 0.7332369888812342 1.12453593807184 1.3681169365833985 1.1505227804668718 1.3176764042193854 1.0 17.18718701549713 -6.997014946721283 24.991525022331402 1.2251517388436695 1.0050622109104588 0.11822172713733126 0.25385547541774744 211.54634463242846 1771088.9723765673 0.10202960423860324 0.0895151352471075 1.0068970147895296e-07 6.997014946721283 -0.22008952793321068 ELVGPPLAETVFT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ELVGPPLAETVFTPK 15 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 ELVGPPLAET(0.018)VFT(0.982)PK;ELVGPPLAETVFT(1)PK;ELVGPPLAETVFT(1)PK 193.64 3.6415e-09 30138900.0 136426.0 224915.0 158833.0 151647.0 170956.0 103589.0 157966.0 101670.0 108419.0 114076.0 True False 159520.22726367644 247243.0747885486 162620.1810975066 143150.7102362075 137458.3990179142 98156.6104819876 143002.31690519833 99001.2702282694 110004.42276640351 134757.07577488074 1.1837614191789374 1.8347316707998476 1.2067654344857761 1.062287151996002 1.0200458731202076 0.7283967088003879 1.0611859606102743 0.7346647265755201 0.8163164875302881 1.0 17.04000150190307 -5.739159246440443 1.804294894391755 0.8824827867272335 1.512664035860113 0.6146887366659244 0.18799367547384058 0.20876832586535268 1.3818760804737102 0.05552140063600038 0.1176801544330619 1.8232270416152952e-06 5.739159246440443 0.6301812491328797 ELVGPPLAETVFT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 ELVGPPLAETVFTPK 15 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 ELVGPPLAET(0.013)VFT(0.987)PK;ELVGPPLAETVFT(1)PK;ELVGPPLAETVFT(1)PK;ELVGPPLAET(0.001)VFT(0.999)PK 194.32 3.3759e-09 30707800.0 121731.0 176572.0 124289.0 131502.0 148533.0 147455.0 143313.0 153322.0 123478.0 104723.0 True False 119995.09361726845 176163.15838255116 114070.43818941432 141173.0957578119 139796.58096711367 141148.69338439358 150733.0459041055 160445.89984947967 109570.60735901604 122824.23101537357 0.9769659669373301 1.4342703953953622 0.9287291053760917 1.1493912446326788 1.1381840522137339 1.149192567439941 1.2272256431651394 1.306304940996513 0.8920927609577411 1.0 16.906235681050433 -8.276087161982606 24.929932816676395 0.9460463500427506 1.16525949441234 0.2804593516506728 0.13948713266794158 1096.219275771581 1865701.5232308006 0.12467033427772789 0.03273827100717631 5.295571522270023e-09 8.276087161982606 0.21921314436958939 ELVGPPLAETVFT(ph)PKT(ph)SPENVQDR ddPTM_PC-9_AZD4547_30min_R2 1 ELVGPPLAETVFTPKTSPENVQDR 24 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 2 ELVGPPLAET(0.032)VFT(0.828)PKT(0.57)S(0.57)PENVQDR 60.635 0.006539699999999999 2597400.0 6936.9 6678.7 6770.7 8838.8 9743.8 6591.9 6894.0 6771.7 6705.1 7235.5 True False 9142.689903516506 8837.459165903174 6680.916094103209 6801.1512180987165 8391.041560230786 6179.707450932822 7507.55264455236 5725.289363185565 7059.5178972670465 6982.187347314799 1.3094306194795233 1.265714986765841 0.9568514509529091 0.9740717170406914 1.2017783457869835 0.8850675502583595 1.0752436551906053 0.8199850674856769 1.0110754046125656 1.0 12.769463352726598 -5.230528691936889 6.406269554777269 0.9901885035765396 1.2914672910755325 0.5984819289971415 0.09735984135724945 0.1274578584070927 17.704409959831573 0.024560268660072906 0.06407815185773666 5.881272578639626e-06 5.230528691936889 0.30127878749899284 ELVGPPLAETVFT(ph)PKT(ph)SPENVQDR ddPTM_PC-9_Lapatinib_30min_R1 1 ELVGPPLAETVFTPKTSPENVQDR 24 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 2 ELVGPPLAET(0.07)VFT(0.821)PKT(0.554)S(0.554)PENVQDR 61.963 0.0049461999999999996 8727700.0 19727.0 22228.0 18138.0 19720.0 19604.0 19371.0 15552.0 17084.0 18494.0 14950.0 True False 19445.689362511268 22176.532431684238 16646.76365470474 21170.27458399155 18450.931262946924 18542.54748600651 16357.20646347957 17877.78500820827 16411.010969546332 17534.087580377174 1.1090220277143712 1.2647668337474565 0.9493943484880583 1.2073781704891062 1.0522892154135133 1.057514250513835 0.9328803901826817 1.01960167167271 0.9359489562440817 1.0 14.097874738710823 -6.801539284345622 1.5860869765810401 0.9734025397412577 1.1301201672449788 0.41439645189838714 0.08192982458883788 0.3697882528374508 1.928761251483101 0.034978442599769094 0.03077247525983418 1.5792857461187532e-07 6.801539284345622 0.1567176275037211 ELVGPPLAETVFT(ph)PKTS(ph)PENVQDR ddPTM_PC-9_Lapatinib_30min_R1 1 ELVGPPLAETVFTPKTSPENVQDR 24 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 2 ELVGPPLAET(0.107)VFT(0.718)PKT(0.509)S(0.665)PENVQDR 77.53 0.00077841 6308400.0 18269.0 22324.0 20317.0 17428.0 21386.0 19386.0 17838.0 18089.0 16981.0 16114.0 True False 18008.48070987572 22272.31014958246 18646.61468588798 18709.713258103693 20128.11752649373 18556.905970973203 18761.564357995663 18929.480977141153 15068.420962142649 18899.283429444655 0.9528657939389868 1.17847378884655 0.9866307765318222 0.9899694519081281 1.0650201422523025 0.9818841037148511 0.9927130003651657 1.0015978144255697 0.797301179084197 1.0 14.206043914927827 -8.073328889670506 9.2375567245314 0.8981873710933802 1.0228557234497582 0.2926746930266223 0.07511332827280419 0.5233107544861693 62.58129517869961 0.04830396014634588 0.01822733537487972 8.446389608110916e-09 8.073328889670506 0.12466835235637796 ELVGPPLAETVFTPKT(ph)S(ph)PENVQDR ddPTM_PC-9_AZD4547_30min_R2 1 ELVGPPLAETVFTPKTSPENVQDR 24 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 2 ELVGPPLAET(0.223)VFT(0.463)PKT(0.657)S(0.657)PENVQDR 66.889 0.0041588 6616000.0 20918.0 13641.0 21346.0 25010.0 21554.0 20190.0 20103.0 20732.0 20060.0 21978.0 True False 27569.488878570886 18050.18648570608 21062.938092771383 19244.33090064815 18561.599149121947 18927.516108304695 21892.128055328707 17528.345773965648 21120.330646698338 21208.556909582563 1.2999229035764472 0.8510803711284358 0.9931339592112755 0.9073852116714775 0.8751938770871933 0.8924471471113041 1.0322309126764437 0.82647517455777 0.9958400628925222 1.0 14.372358838691481 -4.75432342049458 24.999583878979543 0.9265070711965676 1.2999235513086098 0.7287774695376222 0.0675864802177504 119.58271878777668 420078.450869321 0.01556138617335405 0.15326771113517745 1.760664385654255e-05 4.75432342049458 0.3734164801120422 ELVLDNS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 ELVLDNSR 8 0 P39687;H0YN26;H7BZ09 P39687 ANP32A Acidic leucine-rich nuclear phosphoprotein 32 family member A 1 ELVLDNS(1)R;ELVLDNS(1)R 88.338 0.011051 4339500.0 27581.0 32667.0 39158.0 28722.0 29283.0 35608.0 33427.0 43828.0 39159.0 26431.0 True False 36351.184279561305 43225.96891199769 38638.73933461731 22100.586650476464 25217.560911373206 33381.42613098133 36401.93824332056 37055.38966724711 41228.86479531703 25505.65873497027 1.4252203660876621 1.6947599495923418 1.5149085046621655 0.8664973871141315 0.98870455271943 1.3087851005084123 1.42721027602438 1.4528301367273155 1.6164595168361209 1.0 14.638529741268519 -5.549686495999343 24.99518798105189 1.2515536542825922 1.5712015467891123 0.27441136279567113 0.2291317529720331 293.5069094494029 273660.53407985833 0.0679065964534403 0.11762115649948836 2.8204181708326636e-06 5.549686495999343 0.31964789250652004 ELVLDNS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 2 ELVLDNSR 8 0 P39687;H0YN26;H7BZ09 P39687 ANP32A Acidic leucine-rich nuclear phosphoprotein 32 family member A 1 ELVLDNS(1)R;ELVLDNS(1)R 74.392 0.02785 3462100.0 17603.2 27518.0 29743.0 22724.0 22950.5 20994.0 20737.1 21566.9 21177.0 12512.1 True False 17352.175139968476 27454.28376170088 27297.64535130021 24395.198765041783 21600.596712419076 20096.135559404294 21810.76557059043 22568.976907839326 18791.82325630381 14674.799813674728 1.182447144784819 1.8708455386299427 1.860171566079073 1.6623871585838663 1.471951712233276 1.369431666159949 1.486273465227515 1.537941041404081 1.2805505693367367 1.0 13.841053202490324 -8.714271463786844 0.3772362832154455 0.9463951238530863 1.6657450549133213 0.4531364258730698 0.19626113200847184 1.6766028084685531 0.5774998525182571 0.39884455787189205 0.18013616833994864 1.9307610818807088e-09 8.714271463786844 0.7193499310602349 ELVLDNSR ddPTM_PC-9_Lapatinib_30min_R1 2 ELVLDNSR 8 0 P39687;H0YN26;H7BZ09 P39687 ANP32A Acidic leucine-rich nuclear phosphoprotein 32 family member A 0 ; 117.81 0.016266 14459500.0 84378.0 83493.0 95485.0 84688.0 107028.0 96626.0 91596.0 89394.0 109115.0 84359.0 False True 83174.75424697004 83299.67708829448 87634.5918827591 90916.23803088607 100732.8234651441 92493.53122620736 96338.39269732987 93547.57158884149 96825.31966811123 98940.34074869793 0.8406556275991462 0.8419182353522542 0.8857316562649131 0.9188995847690422 1.0181168035493122 0.9348414461310068 0.9737018486930741 0.9454947383539569 0.9786232686831076 1.0 16.594271247669496 -5.757055770666369 1.9420204945005601 0.970343039891363 0.8427304642070566 0.8284248593089714 0.024463888774096953 0.12633757812120722 0.9716540795664532 0.007241196329462969 0.014542279607161887 1.7496219935062466e-06 5.757055770666369 -0.1276125756843064 ELVS(ph)VMDLSLAK ddPTM_PC-9_Lapatinib_30min_R1 1 ELVSVMDLSLAK 12 0 H7C525 H7C525 CCDC58 1 ELVS(0.81)VMDLS(0.19)LAK 68.44 0.030388 3831100.0 25005.0 33498.0 38782.0 29365.0 31973.0 30491.0 26448.0 36785.0 31480.0 24766.0 True False 24648.424114644604 33420.43743911097 35593.4936628492 31524.600058768352 30092.411001336553 29186.971007992568 27817.348028942124 38494.16539024473 27934.39090090399 29046.77010137934 0.8485771061159784 1.150573276218547 1.225385594977356 1.0853048359160369 1.0359985256986475 1.0048267296544124 0.9576743965629818 1.3252477041644213 0.9617038591005845 1.0 14.826090129486056 -11.219142185141484 2.3777988716316725 0.9856763256945956 1.0756143326901668 0.017526150436279364 0.1324660775458175 21706289.195011962 15600111.272601113 1859630.3527336137 0.033924564245746434 6.037509329529142e-12 11.219142185141484 0.0899380069955712 ELVSDANQHVK ddPTM_PC-9_Lapatinib_30min_R1 1 ELVSDANQHVK 11 0 P30153;C9J9C1;B3KQV6 P30153 PPP2R1A Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform 0 70.72800000000001 0.033989 0.0 27135.0 20661.0 30095.0 26332.0 29635.0 26271.0 24569.0 26868.0 28330.0 20650.0 False True 26748.049924050447 20613.16072390806 27620.70527005948 28268.543120976956 27891.92756465171 25147.45057069211 25841.06260295973 28116.38536645632 25139.177071874536 24219.324985604577 1.1044093896072202 0.8511038493500566 1.140440754912724 1.1671895537047026 1.151639345077951 1.0383216949951823 1.0669604796301746 1.1609070600922227 1.03798008767035 1.0 14.563871035932163 -5.292376837868258 24.99829098636572 1.102690543178816 0.9777565031429335 0.25467348391718214 0.07975273781446053 709.8375211307942 573566.4076283594 0.01990838973775142 0.04144965901229506 5.100622262701805e-06 5.292376837868258 -0.1249340400358826 ELVSSKVS(ph)GAQEMVSSAK ddPTM_PC-9_AZD4547_30min_R2 1 ELVSSKVSGAQEMVSSAK 18 1 O60664-3;O60664;K7ERZ3;K7EL96;K7ER39 O60664-3 PLIN3 Perilipin-3 1 ELVS(0.061)S(0.088)KVS(0.769)GAQEMVS(0.061)S(0.021)AK 50.255 0.033118 17414000.0 16738.0 18901.0 21869.0 45945.0 32658.0 27885.0 24786.0 32418.0 23987.0 28674.0 True False 22060.335827972067 25010.37862079984 21579.002771049232 35353.090093173894 28124.000418113777 26141.34654185616 26991.905983155633 27408.542991530903 25254.90384956894 27670.131987686353 0.7972616768792165 0.9038763758673017 0.7798662753272095 1.277662502979985 1.0164028285311182 0.9447496149815792 0.9754888771462117 0.9905461601602819 0.9127135302718387 1.0 14.756041905229388 ELVSSKVS(ph)GAQEMVSSAK ddPTM_PC-9_Lapatinib_30min_R1 2 ELVSSKVSGAQEMVSSAK 18 1 O60664-3;O60664;K7ERZ3;K7EL96;K7ER39 O60664-3 PLIN3 Perilipin-3 1 ELVS(0.092)S(0.081)KVS(0.823)GAQEMVS(0.003)S(0.001)AK;ELVS(0.014)S(0.014)KVS(0.963)GAQEMVS(0.007)S(0.003)AK 57.293 0.016366 39635000.0 75962.0 53467.0 61052.0 41641.0 55456.0 54769.0 50720.0 54343.0 47298.0 51059.0 True False 74878.76795027526 53343.200446502706 56032.54022753524 44703.41805030389 52194.18711069093 52426.65754277475 53346.033425133995 56867.97416887507 41970.80116997958 59884.48011815903 1.2503868749053304 0.8907683650463423 0.9356771590398135 0.7464942162326341 0.8715812011343463 0.8754631824360981 0.8908156724392711 0.9496279178957212 0.7008627458594667 1.0 15.869894536858785 -4.75377814104325 4.46311249311761 0.8684120772638305 1.28635903315967 0.6401761466184464 0.08484445774865668 0.13311881006670334 5.6888584027494105 0.020093961144393005 0.1815099293466969 1.7628763802837657e-05 4.75377814104325 0.4179469558958394 ELVVTQLGYDTR ddPTM_PC-9_Lapatinib_30min_R1 1 ELVVTQLGYDTR 12 0 Q01813;B1APP6;Q01813-2;V9GY25 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 0 84.68700000000001 0.046414 3600600.0 26646.0 18565.0 22079.0 19745.0 18158.0 16579.0 17627.0 18507.0 20616.0 20214.0 False True 26266.02315372206 18522.01388313021 20263.74984740467 21197.113167389118 17089.98214000154 15869.954817536614 18539.639810426608 19366.90278312517 18294.00898389569 23707.962966538067 1.107898776069226 0.7812570784454397 0.8547233634541005 0.8940925543585159 0.7208540929527648 0.6693934371306305 0.7820005386626366 0.8168944253228351 0.7716398498561959 1.0 14.533084088580907 -4.759281196212264 24.98875101627278 0.8003288735939519 1.1078991731000307 0.5066849613782145 0.0876792030661576 46.091856242518844 533551.6361809184 0.021756516082746452 0.13968915630875997 1.740679456429391e-05 4.759281196212264 0.30757029950607884 ELYQQLQR ddPTM_PC-9_Lapatinib_30min_R1 1 ELYQQLQR 8 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 107.01 0.017586 4086800.0 15217.0 20152.0 17979.0 14967.0 16179.0 14502.0 14238.0 18814.0 17570.0 15911.0 False True 15000.002789543976 20105.3392821352 16500.83602094698 16067.723108448356 15227.383029137845 13881.783265813128 14975.17397293095 19688.167123883763 15591.081579697693 18661.195149925163 0.8038071875371889 1.077387547828941 0.8842325418269447 0.861023261337728 0.8159918433305121 0.7438850059862752 0.8024766823678496 1.0550324867034424 0.83548140697517 1.0 14.187753765613445 -10.451576817263025 16.527842316328556 0.9999999999999998 0.8787642135878239 0.11531859770409425 0.10310717368151305 0.0 0.0 0.10352382113086032 0.02510821466412275 3.535274842348285e-11 10.451576817263025 -0.12123578641217592 EMDMSPEEVVAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 EMDMSPEEVVASPR 14 0 Q13049 Q13049 TRIM32 E3 ubiquitin-protein ligase TRIM32 1 EMDMS(0.001)PEEVVAS(0.999)PR 76.156 0.0099438 5359100.0 19851.0 20819.0 26648.0 27612.0 28594.0 25870.0 23681.0 32877.0 24285.0 24362.0 True False 26163.205073549616 27548.334612265564 26294.630108506102 21246.48000114741 24624.216668367473 24252.344810393384 25788.563123824268 27796.615088301613 25568.655521189885 23509.09379521569 1.1128972176236782 1.1718161002816663 1.1184876089888796 0.9037558055713427 1.0474336817431356 1.0316154685353696 1.0969611737681046 1.1823771401158165 1.0876070232189612 1.0 14.520931308062044 -5.539392414005745 24.969338393844637 1.0549954563033397 1.1430555425227351 0.24292078902436753 0.06876711407630778 349.78924535874796 528893.6497583715 0.02032615242448716 0.035217606689035674 2.8880691401245335e-06 5.539392414005745 0.08806008621939543 EMDMSPEEVVAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 EMDMSPEEVVASPR 14 0 Q13049 Q13049 TRIM32 E3 ubiquitin-protein ligase TRIM32 1 EMDMSPEEVVAS(1)PR 103.14 0.0011343 2214400.0 11764.0 13467.0 13204.0 12297.0 12302.0 12435.0 11623.0 13196.0 14174.0 10668.0 True False 11596.243202746618 13435.817988910007 12118.418088913959 13201.362401589464 11578.420546662572 11903.184037400792 12224.782068224227 13809.134334366443 12577.574861163068 12511.949585783514 0.9268134532705158 1.0738388847231468 0.9685475477525343 1.0551003511546502 0.9253890025115152 0.9513452684404657 0.9770485394310112 1.1036756693822387 1.0052450079765443 1.0 13.611018984288918 EMDRETLIDVAR ddPTM_PC-9_AZD4547_30min_R2 2 EMDRETLIDVAR 12 1 P40227-2;P40227 P40227-2 CCT6A T-complex protein 1 subunit zeta 0 ; 108.98 0.0017715 3769800.0 23607.0 18258.1 29084.0 44543.0 31043.0 31145.0 27489.0 34830.0 24011.0 30379.0 False True 31113.53494389631 24159.673768394536 28698.32715685199 34274.299532489844 26733.21529118458 29197.498226505682 29935.467746750775 29447.82381377696 25280.172440571958 29315.440456647946 1.0613360897615511 0.8241279473225782 0.9789492059411984 1.1691551959853759 0.9119158666818602 0.9959767880575877 1.0211501952706368 1.004515823575115 0.8623500805985367 1.0 14.839373112553595 -10.427904772361904 14.680617876785611 0.9999983012153434 0.9821830179778357 0.00353958439625246 0.09365924175537828 0.0 0.0 0.08961610048428224 0.02173509694427422 3.733320092341897e-11 10.427904772361904 -0.017815283237507695 EMDRETLIDVAR ddPTM_PC-9_Lapatinib_30min_R1 2 EMDRETLIDVAR 12 1 P40227-2;P40227 P40227-2 CCT6A T-complex protein 1 subunit zeta 0 ; 140.63 9.8516e-05 6999100.0 37525.0 36559.0 45642.0 37485.0 38363.0 45573.0 35285.0 33034.0 43410.0 33974.0 False True 36989.88661875779 36474.34988167828 41889.49094321498 40241.77194629429 36106.563764559934 43623.94902585175 37111.884649169035 34568.880236545985 38520.70867243462 39846.36063249057 0.9283128002560007 0.9153746867395773 1.0512752050198142 1.009923398461673 0.90614458112189 1.0948038499225183 0.9313745109988325 0.8675542681395764 0.966730914969057 1.0 15.28216034122498 -8.578501936726672 20.406590990770212 1.0000000018284025 0.9642959986983536 0.026421025487129324 0.06647706421223067 25738.218830501293 9442621.502248771 0.06595878402576122 0.01703048488761583 2.639356552187099e-09 8.578501936726672 -0.035704003130048956 EMDT(ph)ARTPLSEAEFEEIMNR ddPTM_PC-9_Lapatinib_30min_R1 1 EMDTARTPLSEAEFEEIMNR 20 1 F8WJN3;Q16630-3;Q16630;Q16630-2 F8WJN3 CPSF6 Cleavage and polyadenylation specificity factor subunit 6 1 EMDT(0.984)ART(0.016)PLSEAEFEEIMNR 64.83 0.0043401 2551300.0 4720.3 5386.4 7289.0 5027.3 5738.9 8535.7 5438.4 4884.0 7474.5 4608.0 True False 4652.987656402994 5373.928121739427 6689.726556353671 5397.024412581175 5401.349185111512 8170.648008688541 5719.973741704432 5110.928469918589 6632.6431000256325 5404.486660225953 0.8609490501006177 0.9943457093323184 1.2378098008061296 0.9986192495025114 0.9994194684321214 1.5118268435779505 1.058375031952672 0.9456825025644359 1.2272475661450393 1.0 12.399941876180305 -4.9873840604753985 4.205121426594791 1.1235600080387893 0.8767571309967878 0.21061479803483607 0.16048881105334198 0.3125518769561412 13.16409395415051 0.04131318405904411 0.17027133180526102 1.0294753198841203e-05 4.9873840604753985 -0.24680287704200154 EMDTART(ph)PLSEAEFEEIMNR ddPTM_PC-9_AZD4547_30min_R2 1 EMDTARTPLSEAEFEEIMNR 20 1 F8WJN3;Q16630-3;Q16630;Q16630-2 F8WJN3 CPSF6 Cleavage and polyadenylation specificity factor subunit 6 1 EMDT(0.353)ART(0.647)PLSEAEFEEIMNR 75.682 0.012975 0.0 7927.1 5950.4 8730.1 8568.7 9588.8 9735.1 5753.8 9087.3 4831.5 7152.4 True False 10447.752906077025 7873.750433585906 8614.333169853993 6593.318600095314 8257.560634736034 9126.36265804641 6265.877053412444 7683.066590379994 5086.8832262972555 6901.996653021123 1.513729060054508 1.1407931399299402 1.2480929219348942 0.9552769917976278 1.1964017153096642 1.3222786270189864 0.9078354233437308 1.1131657948598082 0.7370161827115113 1.0 12.752798058830908 -1.5228787452803376 0.26380291445966186 0.9487964866176296 4.078013561428762 0.4484861477357531 0.15779296037546467 52.03993948156228 0.7215949756764346 0.18966338936403757 73.5630782337634 0.029999999999999995 1.5228787452803376 3.129217074811132 EMDTART(ph)PLSEAEFEEIMNR ddPTM_PC-9_Lapatinib_30min_R1 1 EMDTARTPLSEAEFEEIMNR 20 1 F8WJN3;Q16630-3;Q16630;Q16630-2 F8WJN3 CPSF6 Cleavage and polyadenylation specificity factor subunit 6 1 EMDT(0.454)ART(0.546)PLSEAEFEEIMNR 60.938 0.0091573 1881000.0 3008.1 2991.6 3715.8 2897.9 3554.1 2013.8 2259.3 2977.4 3760.2 2846.9 True False 2965.2039423820192 2984.673134003358 3410.3012674027927 3111.021233111012 3345.0548256294455 1927.6744683970833 2376.2754991601983 3115.7408735330887 3336.6866793386016 3338.9828717441987 0.8880560506838039 0.8938869256445875 1.0213593176119946 0.9317272213157219 1.0018185040530247 0.5773238565282354 0.7116764567045811 0.9331407177616056 0.9993123078213343 1.0 11.705192977370368 EMEADERDR ddPTM_PC-9_AZD4547_30min_R2 1 EMEADERDR 9 1 P49756 P49756 RBM25 RNA-binding protein 25 0 81.95 0.021369 2526600.0 13762.0 11970.0 17345.0 27607.0 21322.0 20232.0 12643.0 17912.0 17892.0 18790.0 False True 18138.02973261748 15839.068413892068 17114.993966978338 21242.632673898184 18361.808344510435 18966.889841665205 13768.202507263632 15144.111976812314 18837.73459275806 18132.167819230886 1.000323288061584 0.8735341836563651 0.9439022480713123 1.171544014244582 1.0126648135826315 1.0460354233843465 0.7593246789091123 0.8352069166683171 1.0389124334476352 1.0 14.146263798569183 -7.217007323688753 24.998797593823618 0.8946279357012641 1.00662079058115 0.18116481509513738 0.10209514344377826 738.1515688940626 415306.56412543805 0.04088200363241857 0.03166690606794745 6.067260980273144e-08 7.217007323688753 0.11199285487988586 EMEADERDR ddPTM_PC-9_Lapatinib_30min_R1 1 EMEADERDR 9 1 P49756 P49756 RBM25 RNA-binding protein 25 0 82.749 0.01986 3239700.0 26535.0 22754.0 24080.0 23181.0 24803.0 23781.0 18144.0 18823.0 23819.0 20787.0 False True 26156.606034076973 22701.314511001598 22100.235351488052 24885.8080695491 23344.136304574196 22763.942066218595 19083.407540726163 19697.58529673987 21136.253394810417 24380.005253063577 1.0728712222402064 0.9311447752107832 0.906490180050759 1.0207466245899175 0.9575115371084995 0.9337135833208277 0.7827482948687287 0.8079401580221024 0.8669503216023486 1.0 14.573410816359418 -7.055144314223125 5.025422047503022 0.8484228807666336 0.9715671200733685 0.36189913041003763 0.06935844113469714 0.21097270464878204 11.382870479971288 0.026048426863823557 0.020466959277637677 8.807561528240652e-08 7.055144314223125 0.1231442393067349 EMEAELEDER ddPTM_PC-9_AZD4547_30min_R2 2 EMEAELEDER 10 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 202.44 0.00067685 24394000.0 95620.0 77291.0 129337.0 214117.0 164270.0 157583.0 106664.0 165769.0 103895.0 149438.0 False True 126025.17098044485 102273.80424211637 127621.90687270547 164755.6337246734 141463.94600660016 147729.31009881024 116156.8893644519 140153.21004266434 109386.67759415382 144206.22110538726 0.8739232608303664 0.7092190854052941 0.8849958475746909 1.1425001810724131 0.9809836560602818 1.0244309085032348 0.8054915278555379 0.9718943397056293 0.758543402328066 1.0 17.137773878712444 -5.518397958714011 24.845561553859493 0.9562241704165048 0.7929552175965497 0.2654536868146362 0.10839345013510551 215.81418715277886 1196668.3688260124 0.02955571440383284 0.05293400137659967 3.0311124004902192e-06 5.518397958714011 -0.16326895281995502 EMEAELEDER ddPTM_PC-9_Lapatinib_30min_R1 2 EMEAELEDER 10 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 187.5 0.00064517 33798000.0 84744.0 70247.0 82309.0 69991.0 76521.0 77447.0 75071.0 62674.0 88751.0 58310.0 False True 83535.53501985353 70084.34738746296 75541.8717419283 75138.37162313152 72020.18522607438 74134.7723477747 78957.80905477602 65586.06284268579 78754.92779053788 68388.80580680878 1.2214796564196877 1.0247926771150808 1.1045941049961625 1.098694014856606 1.0530990324575027 1.084019109168212 1.1545428834921254 0.9590175185681638 1.1515762976328656 1.0 16.061472577048505 -1.9171640287735041 0.011206984916957579 2.524268875259878e-07 2.3137885751637666 0.17575819315473296 0.0680645374000498 17341.58106049031 16.06160810705037 1417.9854107433655 1934.7927911643978 0.012101409888237567 1.9171640287735041 2.313788322736879 EMEAELEDERK ddPTM_PC-9_AZD4547_30min_R2 1 EMEAELEDERK 11 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 84.81700000000001 0.010948999999999999 7135700.0 13580.0 9954.9 11190.0 19883.0 18698.0 17961.0 12723.0 19452.0 17146.0 14900.0 False True 17898.157518452655 13172.626746320313 11041.613288583889 15299.281539287771 16102.10545097346 16837.895830671634 13855.322352283101 16446.140362491802 18052.302555747236 14378.355535207025 1.2447986471489731 0.9161427893520682 0.7679329713017079 1.0640494667019296 1.1198850530261015 1.171058525395491 0.9636235742228506 1.1438123311265724 1.2555192776770707 1.0 13.81161106249865 -5.986075102847868 24.99179093204331 1.1101875368264797 0.961229024626334 0.16132796642348446 0.1339706732187291 388.0193613366123 696394.2305769697 0.03819365575909449 0.05662097477646638 1.0325828250521808e-06 5.986075102847868 -0.14895851220014578 EMEAELEDERK ddPTM_PC-9_Lapatinib_30min_R1 3 EMEAELEDERK 11 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ;; 92.611 0.0047791000000000005 12950900.0 51349.0 45187.0 47786.0 38961.7 43886.0 41841.0 41745.0 41813.9 42273.0 37658.7 False True 50616.75384374665 45082.37227778099 43857.21953929434 41827.07339042111 41304.7117631957 40051.557966134824 43906.35184014629 43756.72644314675 37511.76958557544 44167.95611793643 1.1460062518761511 1.0207031576784513 0.9929646602208088 0.9470004289701623 0.9351737185416651 0.9068012533609189 0.9940770571974938 0.9906894112625084 0.8492982895883213 1.0 15.430712452435959 -4.258145537999292 0.9792149333995217 0.9453067653610333 1.507563942403907 0.6597585213601145 0.04349605016041854 2.8603183022741985 1.078370112093964 0.013909819400922814 2.169792779634114 5.518924616033464e-05 4.258145537999292 0.5622571770428736 EMEENFAVEAANYQDTIGR ddPTM_PC-9_Lapatinib_30min_R1 3 EMEENFAVEAANYQDTIGR 19 0 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 0 ;; 170.35 5.985300000000001e-07 14633100.0 40028.8 31825.1 44148.5 32503.9 41589.0 43334.9 38881.7 37045.1 44094.6 40506.4 False True 39457.98197161712 31751.410936278302 40518.780748138255 34894.345235831825 39142.81678711997 41481.567345585805 40894.804176380785 38766.35058578647 39128.20181127701 47507.877268614684 0.8305566200846528 0.6683399209093764 0.8528855229426623 0.7344959876555928 0.8239226637258963 0.8731513536385667 0.860800493045756 0.8159983736296473 0.8236150310408928 1.0 15.535879125711814 -14.522878745274832 0.10760308267115566 1.6135705647750689 0.6943692898117717 0.5498860469324109 0.05521724327940614 126.50617362532903 0.9068123550764992 17.161483641579206 0.7260469374295965 3.0000000000380277e-15 14.522878745274832 -0.9192012749632972 EMEHNTVCAAGT(ph)SPVGEIGEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EMEHNTVCAAGTSPVGEIGEEK 22 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 EMEHNTVCAAGT(0.5)S(0.5)PVGEIGEEK 76.156 0.00082262 15917000.0 18722.0 37219.0 63489.0 84838.0 94783.0 89852.0 77216.0 70144.0 76564.0 56830.0 True False 21891.26482364468 40913.856348198155 65002.81854337333 80084.80190850691 76210.9515554586 85140.00294459399 69901.5414845715 68302.79432371136 77683.60365514288 67132.82913396755 0.32608881684338614 0.6094463301487283 0.9682716992852535 1.1929305369909695 1.1352262751116167 1.2682320117135546 1.0412423010667229 1.0174276163366969 1.1571626677630498 1.0 16.03473082177749 -5.134647867589139 1.8535493632459947 1.121712921502115 0.2969056166302336 0.9137972775833121 0.08060953915204623 0.12085667971125491 0.6759749094640072 0.023600055890500588 0.13508609988795653 7.334189590976235e-06 5.134647867589139 -0.8248073048718815 down EMEHNTVCAAGT(ph)SPVGEIGEEK ddPTM_PC-9_Lapatinib_30min_R1 4 EMEHNTVCAAGTSPVGEIGEEK 22 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 EMEHNTVCAAGT(0.906)S(0.094)PVGEIGEEK;EMEHNTVCAAGT(0.923)S(0.077)PVGEIGEEK;EMEHNTVCAAGT(0.998)S(0.002)PVGEIGEEK;EMEHNTVCAAGT(0.999)S(0.001)PVGEIGEEK 162.87 8.4634e-07 107961800.0 332941.0 247454.0 521591.0 315629.0 426668.0 484748.0 332535.0 355641.0 530984.0 302923.0 True False 328193.20028609893 246881.0354665287 478707.8013794848 338841.4095674775 401572.2271015633 464016.4580427799 349752.03519374895 372165.37919130136 471178.9904105975 355282.8369304746 0.923751913043644 0.6948859044233564 1.3473991750216836 0.953722990097001 1.1302888441530516 1.3060480547040423 0.9844326796517672 1.0475185978773596 1.3262081402001489 1.0 18.438608470808276 -5.250261078355583 24.9959036298167 1.1324595248158498 0.8093188984686001 0.4396626289560883 0.14787979530376583 645.8693522498758 1444227.859099043 0.03593321139345484 0.09320598650689066 5.620033724092872e-06 5.250261078355583 -0.3231406263472497 EMEHNTVCAAGTS(ph)PVGEIGEEK ddPTM_PC-9_AZD4547_30min_R2 5 EMEHNTVCAAGTSPVGEIGEEK 22 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 EMEHNTVCAAGT(0.241)S(0.759)PVGEIGEEK;EMEHNTVCAAGT(0.28)S(0.72)PVGEIGEEK;EMEHNTVCAAGT(0.246)S(0.754)PVGEIGEEK;EMEHNTVCAAGT(0.451)S(0.549)PVGEIGEEK;EMEHNTVCAAGT(0.22)S(0.78)PVGEIGEEK 105.37 2.7686e-05 292039800.0 309457.6 270575.5 809083.0 1364042.0 1012379.0 957956.0 635107.0 986911.0 741356.0 952550.0 True False 407858.6796820553 358033.7389827114 798354.0307745592 1049583.1911388205 871827.6507835641 898054.8598834627 691630.292634714 834406.5819086538 780542.5646517293 919201.5144336529 0.44370975599768137 0.3895051665611175 0.8685299341205379 1.1418423214690847 0.9484619390784216 0.9769945390448804 0.7524251013237808 0.9077515308737892 0.8491528270954216 1.0 19.81002164934003 -5.298508875169176 5.073985349325208 0.9338618127873014 0.4131729139394422 0.8190408101288862 0.09690279313815388 0.07246053437502857 4.876823952524402 0.027039876933943392 0.0612768177709302 5.029109883408402e-06 5.298508875169176 -0.5206888988478592 down EMEHNTVCAAGTS(ph)PVGEIGEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EMEHNTVCAAGTSPVGEIGEEK 22 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 EMEHNTVCAAGT(0.275)S(0.725)PVGEIGEEK;EMEHNTVCAAGT(0.217)S(0.783)PVGEIGEEK;EMEHNTVCAAGT(0.301)S(0.699)PVGEIGEEK;EMEHNTVCAAGT(0.226)S(0.774)PVGEIGEEK 113.64 0.00013915 230717000.0 435874.0 639606.0 1204340.0 1512688.0 1585232.0 1516916.0 1366645.0 1225224.0 1294599.0 1009496.0 True False 509658.8592960852 703101.8566712056 1233056.033084886 1427936.9955606665 1274617.1692831272 1437366.2545819995 1237186.4919470346 1193063.168232133 1313530.061234313 1192509.633634061 0.4273834314805053 0.5895984710233063 1.0340008988667568 1.1974217694234994 1.068852723142245 1.2053288409937293 1.0374645680444736 1.000464176206598 1.10148381546525 1.0 20.18556949034737 -5.207061621066407 2.991350351181977 1.092444750602842 0.4526054234551549 0.9208812488711781 0.0679529511101588 0.06490230731612658 1.1311884705029371 0.01857681285083999 0.06072632067546193 6.207809467698345e-06 5.207061621066407 -0.6398393271476872 down EMEHNTVCAAGTS(ph)PVGEIGEEK ddPTM_PC-9_Lapatinib_30min_R1 3 EMEHNTVCAAGTSPVGEIGEEK 22 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 EMEHNTVCAAGT(0.276)S(0.724)PVGEIGEEK;EMEHNTVCAAGT(0.266)S(0.734)PVGEIGEEK;EMEHNTVCAAGT(0.064)S(0.936)PVGEIGEEK 123.68 4.1113e-07 145523000.0 144850.0 95690.0 198179.0 132725.0 168116.0 188467.0 141602.0 141593.0 206958.0 124706.0 True False 142784.41243776298 95468.43568417584 181885.4876130629 142486.03925762078 158227.74740877282 180406.70574803484 148933.4586960927 148171.92769066003 183648.2106756447 146261.26593969995 0.9762284738915743 0.6527253478274638 1.2435656593321842 0.9741884725403949 1.0818157930754295 1.2334551091771095 1.0182699960869643 1.013063347556063 1.255617538216567 1.0 17.158188228632717 -5.2635764050624685 24.999267455710015 1.099311444428097 0.8144769123563919 0.46051611672271564 0.12465699050229412 145.30439293900918 1699816.8222981582 0.030482617284892932 0.06890548272083265 5.450339998811145e-06 5.2635764050624685 -0.28483453207170506 EMEKS(ph)FDEQNVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EMEKSFDEQNVPK 13 1 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 EMEKS(1)FDEQNVPK;EMEKS(1)FDEQNVPK 117.2 0.00056929 11921900.0 111407.0 80396.0 67139.0 114793.0 99917.0 97644.0 84896.0 92706.0 67425.0 66583.0 True False 130266.00471145108 88377.18356134601 68739.84838607526 108361.52037392736 80338.98111018611 92523.37674756208 76854.03628618643 90272.5657301262 68410.96306943193 78653.97082926208 1.6561910776790367 1.1236201126220389 0.8739526772944767 1.377699297714452 1.0214230796380486 1.1763344656610788 0.9771157829147259 1.1477178428293868 0.8697712569138419 1.0 16.263231981186294 -4.76752356945435 4.841015850803208 1.0681818878825775 1.6941230542000727 0.6075378085145156 0.14360951299584324 0.11401918078324202 6.6447393401092265 0.03386464616054283 0.24294927338880826 1.7079550256736284e-05 4.76752356945435 0.6259411663174952 EMFEDTVEER ddPTM_PC-9_Lapatinib_30min_R1 1 EMFEDTVEER 10 0 E9PC52;Q16576 E9PC52 RBBP7 Histone-binding protein RBBP7 0 129.85 0.0010716 2107800.0 14273.0 10157.0 13024.0 10948.0 14666.0 13617.0 9204.6 10755.0 12847.0 9929.0 False True 14069.464402652358 10133.482090544216 11953.216994093867 11753.152441457385 13803.374714465395 13034.632652777376 9681.169149546302 11254.716563057826 11400.035575092554 11645.214420439132 1.2081756414856817 0.8701842426154391 1.0264488537981873 1.0092688736438211 1.1853259387167971 1.1193123786453947 0.8313431423430357 0.9664670959861484 0.9789459569833037 1.0 13.507449583328048 -7.245115344828879 24.714947993784488 0.9413946269081964 1.0612443483701928 0.2754374034972198 0.0991754749982541 1020.872172809307 1545624.7861105546 0.03879282721583406 0.029953493839843342 5.687018685251034e-08 7.245115344828879 0.11984972146199635 EMFPYEAS(ph)TPTGISASCR ddPTM_PC-9_AZD4547_30min_R2 3 EMFPYEASTPTGISASCR 18 0 G5E972;P42167;H0YJH7;P42167-2 G5E972 TMPO Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 EMFPYEAS(0.869)T(0.13)PT(0.001)GISASCR;EMFPY(0.002)EAS(0.443)T(0.443)PT(0.069)GIS(0.044)ASCR;EMFPY(0.001)EAS(0.486)T(0.486)PT(0.019)GIS(0.009)ASCR 140.75 0.00013877 21005100.0 62878.0 59934.0 85535.0 79630.0 82102.0 66008.0 74811.0 110291.0 68422.0 63179.0 True False 82871.89605635239 79306.49342675073 84400.75001242378 61272.53377123601 70703.55448367861 61880.50932525888 81469.03407188965 93248.06018504937 72038.64723371854 60967.12244019092 1.35928829735486 1.3008075541789075 1.3843649927093309 1.0050094431034482 1.1596997144327943 1.014981630237904 1.3362781579827916 1.5294810785358326 1.1815982836386751 1.0 15.895743834035944 -11.873150110857956 1.7122478072130674 4.288471549708766e-05 1.2513281412101551 0.18886586399386818 0.15690073817231143 1710434.7640531852 191018.12775940073 6589454.728783126 0.043372123678977956 1.3392137175405073e-12 11.873150110857956 1.251285256494658 EMFPYEAS(ph)TPTGISASCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EMFPYEASTPTGISASCR 18 0 G5E972;P42167;H0YJH7;P42167-2 G5E972 TMPO Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 EMFPYEAS(0.505)T(0.491)PT(0.004)GISASCR;EMFPY(0.015)EAS(0.623)T(0.36)PT(0.002)GISASCR;EMFPYEAS(0.856)T(0.132)PT(0.01)GIS(0.001)ASCR;EMFPYEAS(0.896)T(0.103)PTGISASCR 183.73 1.4557e-10 22648200.0 72945.0 72976.0 78259.0 58735.0 99588.0 55987.0 55976.0 39566.9 42822.100000000006 33055.6 True False 85293.1477705778 80220.57499841781 80124.99135891009 55444.268371439204 80074.44629843956 53050.943160519375 50673.5480488547 38528.31079959591 43448.292201045995 39048.31861201439 2.1842975780354035 2.054392553889261 2.0519447240490716 1.4198887517369343 2.0506503005689534 1.358597374899432 1.2977139567096099 0.986682965338782 1.1126802317085638 1.0 15.252972808010613 -6.707907902627603 0.5452821310297437 0.9329281723031281 2.1950402817232257 0.8129023143607563 0.19763240488914283 0.38906492960669464 0.24954164312493074 0.16621318933912518 0.21508347654381543 1.959260114145235e-07 6.707907902627603 1.2621121094200975 up EMFPYEAS(ph)TPTGISASCR ddPTM_PC-9_Lapatinib_30min_R1 2 EMFPYEASTPTGISASCR 18 0 G5E972;P42167;H0YJH7;P42167-2 G5E972 TMPO Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 EMFPYEAS(0.491)T(0.491)PT(0.019)GISASCR;EMFPY(0.002)EAS(0.449)T(0.449)PT(0.084)GIS(0.008)AS(0.008)CR 163.44 1.5102e-07 8364300.0 36596.0 43654.0 32804.0 23019.0 22260.2 24899.0 23636.7 17199.8 38366.0 12965.8 True False 36074.13432911551 43552.92184509377 30106.98174710191 24711.894049132956 20950.89880123705 23834.127812403905 24860.492670738648 17998.965498956935 34044.81706810937 15206.92125415747 2.372218131875516 2.864019686640167 1.979820980454598 1.625042547147858 1.3777212659340374 1.5673210516486245 1.6348143227178187 1.183603518301651 2.2387711818262845 1.0 13.892440478637216 -5.517782286439457 2.8262085273571906 1.525405482374714 2.616629199766976 0.6367777639655723 0.32967559067780416 0.1527406579497735 2.4446035418786134 0.0860473497473572 0.18990375748493443 3.0354124672583724e-06 5.517782286439457 1.0912237173922619 EMFPYEAST(ph)PTGISASCR ddPTM_PC-9_Lapatinib_30min_R1 1 EMFPYEASTPTGISASCR 18 0 G5E972;P42167;H0YJH7;P42167-2 G5E972 TMPO Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 EMFPYEAS(0.405)T(0.592)PT(0.002)GISASCR 145.82 0.00060671 5251200.0 16686.0 21084.0 14785.0 10890.0 9861.4 12592.0 12333.0 10374.0 14547.0 5639.9 True False 16448.05458016236 21035.18129339709 13569.434371750443 11690.886927975047 9281.37184025835 12053.469513385677 12971.542394167547 10856.01391214894 12908.563673298928 6614.74920030563 2.486572669966442 3.180042153741093 2.051390606181029 1.7673968542049752 1.4031328413523994 1.8222111146449442 1.961002904474172 1.6411829962725335 1.9514819507748677 1.0 12.691470742098069 -5.456065825208032 3.7918692816605044 1.6937769381262964 2.8263881974752127 0.6876153186055337 0.3138077349743099 0.12104506434444372 3.36724914290974 0.08024881177396108 0.17453165602187948 3.4989213050874843e-06 5.456065825208032 1.1326112593489164 EMGEMHR ddPTM_PC-9_AZD4547_30min_R2 1 EMGEMHR 7 0 B5MCA4;P16422 B5MCA4 EPCAM Epithelial cell adhesion molecule 0 87.75399999999999 0.012029999999999999 731340.0 3636.4 2991.8 3750.0 2742.1 3986.1 2566.9 2959.7 3640.6 1832.3 2419.7 False True 4792.699558181242 3958.840842162263 3700.2725497935253 2109.9512100226834 3432.698820094414 2406.391337216804 3223.1075663013667 3078.028922665415 1929.1516372854105 2334.987039499358 2.052559383459721 1.695444460801407 1.5847079607717636 0.9036243774933653 1.4701147209923764 1.0305801687587763 1.3803535145070567 1.318220988209584 0.8261937238414127 1.0 11.189198826844606 -5.261356042319785 1.5370225411910379 1.1649187787565447 2.043134214803055 0.6628906095812646 0.21544099140945658 0.31598758110920644 1.2165502251017002 0.061493090725200594 0.3169811704697082 5.4782766193811035e-06 5.261356042319785 0.8782154360465104 EMGEMHR ddPTM_PC-9_Lapatinib_30min_R1 3 EMGEMHR 7 0 B5MCA4;P16422 B5MCA4 EPCAM Epithelial cell adhesion molecule 0 ;; 90.777 0.010654 1388330.0 16974.0 13517.9 5921.1 2540.8 4409.280000000001 2454.14 5220.67 1969.27 9252.1 1254.4 False True 16731.94764734962 13486.600133087308 5434.2900141069695 2727.6589078603324 4149.934819378014 2349.182153079759 5490.970747665504 2060.7694733735825 8210.031069067785 1471.2213686170649 11.372828049036228 9.166941441154156 3.6937269468938956 1.854009849261711 2.8207412615811287 1.5967564115031645 3.732253258955155 1.4007201889071852 5.580418585671538 1.0 10.522798623965839 -5.208389561624039 2.5576263213646007 2.588224162734367 11.19606178151991 0.8554415362218974 1.2653273382618921 0.0955467243563967 1.1791804779985056 0.3196668967129909 1.1554307756195117 6.188856863117686e-06 5.208389561624039 8.607837618785544 EMGS(ph)LSIKDPK ddPTM_PC-9_Lapatinib_30min_R1 1 EMGSLSIKDPK 11 1 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 EMGS(0.999)LS(0.001)IKDPK 104.17 0.010886 0.0 17488.0 18505.0 15229.0 14859.0 14403.0 14908.0 12366.0 11264.0 15479.0 10011.0 True False 17238.61791309358 18462.15280944382 13976.93040564001 15951.78042817092 13555.843857387501 14270.41959224536 13006.250972697297 11787.366561253673 13735.592018903846 11741.388011180989 1.4681925081325766 1.5723995145942575 1.1903984769373246 1.358594095773046 1.1545350383173316 1.2153946005920293 1.1077268684342785 1.003915938220328 1.169843974649661 1.0 13.519315346641468 -4.162184176400415 0.300738486904397 1.012431405304939 2.198490471851341 0.757064858803302 0.08820036867179584 5.093296767789676 0.2818226526483179 0.09204159720215666 2.370101311491544 6.883603133321227e-05 4.162184176400415 1.1860590665464021 EMLAS(ph)DDEEDVSSK ddPTM_PC-9_AZD4547_30min_R2 1 EMLASDDEEDVSSK 14 0 E7ETM8;E7EUA0;Q0ZGT2-4;Q0ZGT2-2;Q0ZGT2;Q0ZGT2-3 E7ETM8 NEXN Nexilin 1 EMLAS(1)DDEEDVSSK 146.84 0.00017516 3636900.0 27545.0 27386.0 26598.0 25169.0 27357.0 31704.0 32342.0 34909.0 33850.0 23715.0 True False 36303.73702840782 36237.98893758131 26245.293141175516 19366.675907173656 23558.952766193248 29721.543868137294 35220.375345244036 29514.61617901636 35639.241893855375 22884.74506828422 1.586372796379579 1.5834997868428622 1.1468466466575873 0.8462701179054763 1.0294610097642471 1.298749178959749 1.5390328902573471 1.2897070118522065 1.557336198743481 1.0 14.482098600228655 -5.254013656678215 23.752550214426883 1.2187653325520549 1.5849364125803285 0.32592345237378617 0.21360131201135144 374.01563549062996 1196341.175165687 0.06058491126775952 0.15320585773050005 5.571682281317404e-06 5.254013656678215 0.3661710800282736 EMLAS(ph)DDEEDVSSK ddPTM_PC-9_Lapatinib_30min_R1 4 EMLASDDEEDVSSK 14 0 E7ETM8;E7EUA0;Q0ZGT2-4;Q0ZGT2-2;Q0ZGT2;Q0ZGT2-3 E7ETM8 NEXN Nexilin 1 EMLAS(1)DDEEDVSSK;EMLAS(1)DDEEDVSSK;EMLAS(0.999)DDEEDVSS(0.001)K;EMLAS(0.999)DDEEDVS(0.001)SK 166.09 2.4991e-05 17325500.0 65889.5 88132.0 84144.2 73137.9 93660.8 81748.8 92570.8 95545.7 83100.4 86171.7 True False 64949.90364734553 87927.93576881377 77226.18868200509 78516.7051468823 88151.85588821763 78252.59438976028 97363.66307159694 99985.10202872663 73740.7578659937 101066.36352842703 0.6426460929216773 0.8700019739414311 0.7641136574611552 0.7768826581437042 0.872217549050561 0.7742694172205979 0.9633636718730003 0.9893014702226199 0.7296271013575408 1.0 16.624943400014658 -1.5228787455577197 0.12762437791276374 1.0209749216702673 0.03370761037309032 0.3866657852850921 0.08936585428951857 92.6945256038627 0.8066495383100277 0.4998420805621388 16.410181969571433 0.029999999980839118 1.5228787455577197 -0.9872673112971769 EMLAS(ph)DDEEDVSSKVEK ddPTM_PC-9_Lapatinib_30min_R1 1 EMLASDDEEDVSSKVEK 17 1 E7ETM8;E7EUA0;Q0ZGT2-4;Q0ZGT2-2;Q0ZGT2;Q0ZGT2-3 E7ETM8 NEXN Nexilin 1 EMLAS(0.999)DDEEDVS(0.001)S(0.001)KVEK 62.468 0.043749 7878000.0 73863.0 62070.0 69947.0 67564.0 63166.0 57229.0 59420.0 64119.0 69973.0 60769.0 True False 72809.70007518458 61926.28072856944 64196.22766322813 72532.8819468967 59450.70006913416 54781.449077314865 62496.476855707064 67098.20281791755 62091.90389164405 71272.84068039733 1.0215630439325247 0.8688622501558502 0.9007109447355655 1.0176791222921737 0.8341283931101304 0.7686160472116805 0.8768624381895291 0.941427368088221 0.8711860408381564 1.0 16.121064805724288 -4.7547495409252525 24.741525148230856 0.8930575642644182 1.021563294104757 0.21511950334719476 0.07046263691447761 324.8325827105414 1201227.621589562 0.01812082315280066 0.170662568644639 1.7589377067513613e-05 4.7547495409252525 0.1285057298403388 EMLMEDVGS(ph)EEEQEEEDEAPFQEK ddPTM_PC-9_AZD4547_30min_R2 1 EMLMEDVGSEEEQEEEDEAPFQEK 24 0 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 EMLMEDVGS(1)EEEQEEEDEAPFQEK 78.755 9.0015e-05 2399700.0 11975.0 16355.0 14864.0 10367.0 14524.0 20042.0 16465.0 23926.0 20910.0 12635.0 True False 15782.800904526552 21641.43391054341 14666.893648034935 7977.04831855335 12507.593302488962 18788.77057170096 17930.35310306855 20228.78646478402 22015.259911388952 12192.652495794691 1.2944517946337042 1.7749570011945843 1.2029288666345261 0.6542504447908013 1.0258303766799632 1.5409912304300728 1.4705867414209355 1.65909644941993 1.805616941759156 1.0 13.573724396093903 -6.77956953457655 24.73473344780605 1.534909977417834 1.193855115090461 0.17653194375743897 0.32346478795020583 382.9993323229508 522517.2346183115 0.12300793213304717 0.10870182357382761 1.661232677705724e-07 6.77956953457655 -0.34105486232737303 EMLMEDVGS(ph)EEEQEEEDEAPFQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EMLMEDVGSEEEQEEEDEAPFQEK 24 0 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 EMLMEDVGS(1)EEEQEEEDEAPFQEK 85.06200000000001 1.1309000000000001e-05 1792300.0 37528.0 72210.0 48912.0 35371.0 44437.0 36742.0 46991.0 25101.0 35254.0 32931.0 True False 43880.74918821374 79378.53158073543 50078.24757979297 33389.27754432925 35729.888843673594 34815.18483940562 42539.67229462147 24442.125346707886 35769.523055984566 38901.12961834743 1.1280070686563741 2.040519963289116 1.2873211670484226 0.8583112591306716 0.9184794681854651 0.8949659092414965 1.093533085336369 0.6283140254924612 0.9194983129516664 1.0 15.247524428620197 -5.578922656688081 4.234667844365486 0.8977013281603822 1.604413139809155 0.583178987492093 0.23399715922761002 0.12313399783694239 4.546191116788742 0.060219471258323276 0.1118133136440292 2.6368009307234437e-06 5.578922656688081 0.7067118116487728 EMMSHAEGQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EMMSHAEGQQR 11 0 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 0 65.695 0.025338999999999997 694830.0 1490.7 1207.1 2449.7 3217.0 3337.7 3028.1 2942.0 3408.0 2194.6 2808.2 False True 1743.0460673329314 1326.932910554017 2508.110138538984 3036.761919654722 2683.7016448799277 2869.301105334609 2663.3124617645153 3318.543611074477 2226.6918732247036 3317.304430301032 0.5254404906018099 0.4000033576760404 0.7560687272561786 0.9154305802977354 0.8090007116520183 0.8649495895299039 0.8028544011327988 1.0003735505135212 0.6712353116842642 1.0 11.695795699541172 -5.393800209417522 3.9477377801645863 0.8600528410731837 0.4642226734557362 0.7290407315904446 0.09671183053182193 0.10409522262391595 2.7628914306308894 0.02378462345202575 0.05331181402049626 4.038311266207631e-06 5.393800209417522 -0.3958301676174475 EMPCPLPCDEES(ph)PEAELHNHGIQINSCSVR ddPTM_PC-9_AZD4547_30min_R2 1 EMPCPLPCDEESPEAELHNHGIQINSCSVR 30 0 P23497;P23497-5;P23497-2;P23497-3;P23497-4;E9PHV6;P23497-7;P23497-6 P23497 SP100 Nuclear autoantigen Sp-100 1 EMPCPLPCDEES(0.995)PEAELHNHGIQINS(0.002)CS(0.002)VR 43.985 0.011399 7544400.0 6931.5 5538.3 9884.2 17522.0 11530.0 10485.0 9450.3 12931.0 10490.0 10084.0 True False 9135.572815843492 7328.447167640641 9753.129049778454 13482.5736122014 9929.258522287097 9829.371292499984 10291.358392343082 10932.811074819117 11044.479984240552 9730.962229330718 0.938814949698127 0.7531061158115996 1.0022779679876797 1.3855334441195044 1.020377870993958 1.0101129837779705 1.0575889773082499 1.123507708401727 1.1349833371000737 1.0 13.248366755120305 -5.516910138716087 24.992621534591112 1.107527377622969 0.8538933653611533 0.4545391888991961 0.11260856994389237 217.40883412131774 910364.7380871582 0.030476283850296246 0.05514176164392454 3.0415142901875974e-06 5.516910138716087 -0.2536340122618157 EMPQDLRS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 2 EMPQDLRSPAR 11 1 O43765;K7EMD6 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 EMPQDLRS(1)PAR;EMPQDLRS(1)PAR 63.693999999999996 0.023467 30336000.0 42484.0 47442.0 62647.0 50060.0 64628.0 55055.0 54362.0 52773.0 62990.0 49135.0 True False 41878.17036938858 47332.15096382779 57496.40548441327 53741.57939526455 60826.70810353669 52700.42598947332 57176.59836469111 55225.02623730831 55895.402885893964 57627.91928172788 0.7266993306604932 0.8213406202023925 0.9977178805177457 0.9325615095095828 1.055507623070178 0.9144946867131306 0.9921683634831516 0.958303317656283 0.9699361625852897 1.0 15.814480310151637 -5.071089408555818 2.798078492166581 0.9760033163404203 0.7297948517198396 0.8290474683106392 0.03798728602384416 0.10181878061445894 1.4611681934338565 0.00941133059068576 0.04170033833534517 8.490056715600227e-06 5.071089408555818 -0.24620846462058066 EMQPTHPIR ddPTM_PC-9_AZD4547_30min_R2 4 EMQPTHPIR 9 0 P63104;E7EX29;B0AZS6;P63104-2;B7Z2E6;H0YB80;P27348;P31946-2;P31946 P63104;P27348;P31946-2 YWHAZ;YWHAQ;YWHAB 14-3-3 protein zeta/delta;14-3-3 protein theta;14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed 0 ;;; 114.86 0.0013664000000000003 44965700.0 53285.4 37480.8 64105.3 61962.0 63500.0 55144.1 67446.3 77811.0 52869.3 63880.0 False True 70229.04879482738 49595.73562300801 63255.22183634108 47677.6182033571 54684.12108978579 51695.93070965648 73448.89003920405 65787.09786890037 55663.863263184874 61643.58064355872 1.1392759483085897 0.8045563723785792 1.0261445097114221 0.7734401166447985 0.8871016335988889 0.8386263447053397 1.1915091445434862 1.0672173352372354 0.902995294596037 1.0 15.91166304456036 -7.23930407203187 24.97460319312653 1.0460319205352149 0.904485337266213 0.212853637644423 0.12079599118223504 1130.9582090297265 1276028.2604299702 0.044809580639686625 0.03468485862958024 5.763627806924417e-08 7.23930407203187 -0.14154658326900182 EMQPTHPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 EMQPTHPIR 9 0 P63104;E7EX29;B0AZS6;P63104-2;B7Z2E6;H0YB80;P27348;P31946-2;P31946 P63104;P27348;P31946-2 YWHAZ;YWHAQ;YWHAB 14-3-3 protein zeta/delta;14-3-3 protein theta;14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed 0 ;;;; 120.31 0.0011433 48617400.0 75411.7 85710.0 92551.3 98150.0 116494.0 90025.0 93622.4 94926.0 86134.0 72463.1 False True 88177.41136103235 94218.7223623434 94758.07399475964 92650.9737065934 93667.83695917627 85303.93052004505 84753.8085045217 92434.29308241098 87393.54680048165 85600.08641241588 1.0301089059209483 1.1006848977745591 1.106985728241221 1.0823700955184412 1.0942493271314058 0.9965402383948075 0.9901135858226022 1.079838782370713 1.02095161889703 1.0 16.385324632562565 -6.753106886128767 24.999664491291863 1.0207678140772845 1.085179874881984 0.5332601682110498 0.030473330777118363 155.8914728010629 467714.34930680663 0.010429426079617022 0.010257349917227487 1.765603226817735e-07 6.753106886128767 0.06441206080469963 EMQPTHPIR ddPTM_PC-9_Lapatinib_30min_R1 7 EMQPTHPIR 9 0 P63104;E7EX29;B0AZS6;P63104-2;B7Z2E6;H0YB80;P27348;P31946-2;P31946 P63104;P27348;P31946-2 YWHAZ;YWHAQ;YWHAB 14-3-3 protein zeta/delta;14-3-3 protein theta;14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed 0 ;;;;;; 133.99 0.0007737999999999999 60457500.0 124532.59999999999 116992.2 139343.59999999998 126966.0 122717.5 128678.29999999999 115268.1 110659.8 145234.5 109372.2 False True 122756.74228751795 116721.31174887925 127887.30708985086 136303.50318615983 115499.49792188793 123175.029072768 121236.11820685513 115801.45829146121 128876.66122291423 128277.03904070419 0.9569658233892149 0.9099158557272425 0.996961794926295 1.0625713237963712 0.900391050383056 0.9602266313122706 0.94511160464489 0.9027450209130233 1.004674431111711 1.0 16.968903432653974 EMS(ph)PSPPAAQDPGGTALVSAR ddPTM_PC-9_AZD4547_30min_R2 1 EMSPSPPAAQDPGGTALVSAR 21 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 EMS(0.994)PS(0.006)PPAAQDPGGTALVSAR 180.03 1.625e-41 0.0 6464.6 4130.1 8975.7 9405.5 8600.8 7042.0 6577.5 10652.0 4680.1 5335.6 True False 8520.208327966797 5465.074056492531 8856.676353381808 7237.2072885264415 7406.727380614642 6601.662626779676 7162.884757694106 9005.978158609014 4927.480531386483 5148.802268030246 1.654794238432919 1.0614262836283437 1.720143033725408 1.4056098703699391 1.43853405025946 1.2821744326385338 1.3911749538663831 1.749140419419212 0.9570149084927992 1.0 12.330021151338583 -8.285711578928506 24.76345939669668 0.9785071708723545 1.4469351491917335 0.4886109483996831 0.19767413083005253 655.9849627597171 669254.3717923672 0.17909522530744237 0.04633859162066266 5.17950696094945e-09 8.285711578928506 0.468427978319379 EMS(ph)PSPPAAQDPGGTALVSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EMSPSPPAAQDPGGTALVSAR 21 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 EMS(0.95)PS(0.05)PPAAQDPGGTALVSAR 152.13 2.6487e-16 0.0 4488.0 5695.2 6304.6 8078.6 8087.7 5657.0 5726.4 8329.8 9011.4 4337.5 True False 5247.72975795948 6260.581817734438 6454.925574328649 7625.982233174583 6502.973243040234 5360.336961420656 5183.953936454225 8111.151576152642 9143.174677106123 5123.854414368893 1.0241762028294952 1.2218500588497996 1.2597792701188026 1.4883292179006764 1.2691565210759812 1.0461532525960517 1.0117293578671545 1.5830175723585025 1.7844329556799654 1.0 12.323013769191784 -7.775571522436151 24.999382196898093 1.512794042196136 1.2018765256481896 0.20947220829893043 0.2289090294587096 329.5547987704634 582965.1195034125 0.12405122398222485 0.060046037205764756 1.6765962002590783e-08 7.775571522436151 -0.3109175165479463 EMS(ph)PSPPAAQDPGGTALVSAR ddPTM_PC-9_Lapatinib_30min_R1 1 EMSPSPPAAQDPGGTALVSAR 21 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 EMS(0.762)PS(0.238)PPAAQDPGGTALVSAR 115.38 0.00037415 0.0 6094.5 5141.8 4814.9 5277.4 6288.8 6397.0 4701.9 3425.2 6139.0 4033.3 True False 6007.591312405582 5129.89447801125 4419.037508051486 5665.517600890318 5918.905148256512 6123.415222135337 4945.341375426611 3584.347296307361 5447.561173464093 4730.450530965569 1.2699829060847037 1.084440994453048 0.9341684220402326 1.1976697703112615 1.2512349742400453 1.2944676584294477 1.0454271412531142 0.7577179536799282 1.1515945759931983 1.0 12.207761877917376 -7.518727020045885 24.97163267969997 0.9531082625786471 1.1626376397392557 0.32190167816051685 0.13268941974423984 211.5483510177755 1272436.9082798334 0.0624680253017026 0.03716503375024855 3.0288166215858564e-08 7.518727020045885 0.2095293771606086 EMSPS(ph)PPAAQDPGGTALVSAR ddPTM_PC-9_Lapatinib_30min_R1 1 EMSPSPPAAQDPGGTALVSAR 21 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 EMS(0.032)PS(0.966)PPAAQDPGGT(0.002)ALVSAR 98.654 0.00022247 3193500.0 6898.1 4562.2 8124.0 5129.1 6603.5 7150.4 6519.5 5248.9 6629.2 5130.9 True False 6799.731829043387 4551.636506200731 7456.076079546878 5506.311124176018 6215.095112980519 6844.594060396512 6857.047809841503 5492.783056051533 5882.549687429251 6017.769228505501 1.1299422711050162 0.7563660774228658 1.239009971374156 0.915008687620196 1.0327905369884087 1.1373972315147005 1.1394667275309318 0.9127606671975445 0.9775299557125372 1.0 12.555013067426005 -3.3511495953419845 15.66113513642608 1.0237015888192116 89.13052387071193 0.0 0.13503316377462538 0.0 0.0 0.029407849652857046 0.0 0.0004455027658623368 3.3511495953419845 88.10682228189272 EMT(ph)TKDKTK ddPTM_PC-9_Lapatinib_30min_R1 1 EMTTKDKTK 9 2 H7BYI2;Q9NZC9 H7BYI2 SMARCAL1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 1 EMT(0.994)T(0.006)KDKTK 68.847 0.04018 0.0 0.0 474.99 0.0 0.0 499.05 728.98 498.86 625.27 436.37 0.0 True False 0.0 473.89018983829874 0.0 0.0 469.6968601700501 697.8032247353789 524.6885298592736 654.3223268603595 387.2214154201868 0.0 0.0 EMVLELIR ddPTM_PC-9_Lapatinib_30min_R1 2 EMVLELIR 8 0 Q96AE4;E9PEB5;Q96AE4-2 Q96AE4 FUBP1 Far upstream element-binding protein 1 0 ; 103.56 0.018125 3750200.0 22881.0 17112.1 18763.7 14327.1 21338.9 22421.0 18087.1 18654.4 19737.1 16377.5 False True 22554.712744138502 17072.477983814282 17221.02101597658 15380.76272780453 20083.787855891554 21462.10609590375 19023.561537140005 19521.151525235313 17514.099957123 19208.329053352994 1.174215241809457 0.8888059932956074 0.8965392548276078 0.8007340297577666 1.0455770410901901 1.1173333212009577 0.9903808646915732 1.0162857722300271 0.9117971640571072 1.0 14.229444402910463 ENAEVDGDDDAEEMEAK ddPTM_PC-9_Lapatinib_30min_R1 2 ENAEVDGDDDAEEMEAK 17 0 P05198 P05198 EIF2S1 Eukaryotic translation initiation factor 2 subunit 1 0 ; 298.7 1.3158999999999998e-111 23446000.0 51659.0 68721.0 57795.0 58105.0 70380.0 57839.0 62350.0 61173.0 54251.0 63736.0 False True 50922.33318689967 68561.88074670566 53043.31819515163 62378.23553259784 66240.3867724039 55365.36079929429 65578.17791910686 64015.32090301594 48140.681091643666 74752.68267711837 0.6812107788405416 0.9171828794806892 0.7095841419399397 0.8344614975495948 0.8861272184507157 0.7406471422361609 0.8772685550612379 0.8563615192182379 0.6439993772474927 1.0 16.189837734318747 -11.247128806954404 2.8540743820916736 1.0323485439421205 0.801828302439679 0.3148767402165301 0.09047303025004519 126203642.06866716 108721749.51198252 29071528.192145202 0.021573079057406887 5.660713736111605e-12 11.247128806954404 -0.23052024150244155 ENALSSGTLQEEQRT(ph)PPPGQDTQQFHEK ddPTM_PC-9_AZD4547_30min_R2 2 ENALSSGTLQEEQRTPPPGQDTQQFHEK 28 1 Q12802-2;Q12802;Q12802-4;H0YMW2 Q12802-2 AKAP13 A-kinase anchor protein 13 1 ENALS(0.003)S(0.012)GT(0.012)LQEEQRT(0.971)PPPGQDT(0.001)QQFHEK;ENALS(0.007)S(0.018)GT(0.007)LQEEQRT(0.967)PPPGQDTQQFHEK 80.02 8.375e-06 34422000.0 101623.0 95095.0 123952.0 162777.0 151609.0 141229.0 120334.0 144137.0 130142.0 136658.0 True False 133937.000110288 125832.59906592015 122308.31549120195 125251.27752958039 130560.70731183194 132397.928304099 131043.49288215303 121863.93858875571 137021.0404298413 131873.6450154578 1.015646455321595 0.9541906500815267 0.9274659502804019 0.9497824793945663 0.9900439719894604 1.003975648724806 0.9937049428397353 0.9240962329847728 1.039032783341813 1.0 17.008796744828977 -6.271100908367376 23.55661058274766 0.9887168814890678 0.9587795146870852 0.15369357630061065 0.03377971543456711 614.300925831038 1497776.817213243 0.010461457819800775 0.012026371747320588 5.356721795668531e-07 6.271100908367376 -0.029937366801982557 ENALSSGTLQEEQRT(ph)PPPGQDTQQFHEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ENALSSGTLQEEQRTPPPGQDTQQFHEK 28 1 Q12802-2;Q12802;Q12802-4;H0YMW2 Q12802-2 AKAP13 A-kinase anchor protein 13 1 ENALS(0.012)S(0.044)GT(0.044)LQEEQRT(0.899)PPPGQDTQQFHEK;ENALS(0.011)S(0.011)GT(0.011)LQEEQRT(0.967)PPPGQDTQQFHEK 92.499 4.6134e-08 23213000.0 74911.0 64624.0 80391.0 78109.0 100034.0 82767.0 87708.0 76092.0 78145.0 61843.0 True False 87591.95274030814 71039.4436348628 82307.82632456516 73732.80596279455 80433.0558000774 78426.55281702364 79399.66328906926 74094.66562613823 79287.72278918474 73054.64635108138 1.1989922217864735 0.9724151328235298 1.1266610740816598 1.009282908693502 1.1009984965711468 1.0735327146767133 1.0868530237966714 1.014236182460713 1.0853207393291433 1.0 16.1566884123933 -8.968923029847884 0.00921345679710924 4.05608223202309e-06 2.0845626543466955 0.15107278431385096 0.060037894615411924 5651.040999355836 22.90190135811053 2646.049487296618 2533.211368152503 1.0741797727020137e-09 8.968923029847884 2.0845585982644637 ENALSSGTLQEEQRT(ph)PPPGQDTQQFHEK ddPTM_PC-9_Lapatinib_30min_R1 2 ENALSSGTLQEEQRTPPPGQDTQQFHEK 28 1 Q12802-2;Q12802;Q12802-4;H0YMW2 Q12802-2 AKAP13 A-kinase anchor protein 13 1 ENALS(0.009)S(0.031)GT(0.031)LQEEQRT(0.928)PPPGQDT(0.001)QQFHEK;ENALS(0.003)S(0.013)GT(0.013)LQEEQRT(0.971)PPPGQDTQQFHEK 68.565 0.00012665 36981000.0 65578.0 81691.0 99543.0 79004.0 86407.0 100641.0 83277.0 88542.0 87502.0 69355.0 True False 64642.845694467615 81501.84950858018 91358.95878709205 84814.21770961813 81324.71014269817 96336.81903562945 87588.6755825095 92655.98455846276 77646.60332309091 81342.91934027139 0.7946954230159297 1.001953829166666 1.1231335133783662 1.0426748682921707 0.9997761428072547 1.1843295005510683 1.0767830352401178 1.139078672242717 0.954558847319972 1.0 16.31172914859087 -4.798277922377893 3.072781320788753 1.0714974144824716 0.7569206774205857 0.5920787791855274 0.0670985546007811 0.2261587124607011 3.23203841088271 0.016557031760382354 0.17222550554269855 1.591190135072437e-05 4.798277922377893 -0.31457673706188594 ENARS(ph)PSSVTGNALWK ddPTM_PC-9_AZD4547_30min_R2 1 ENARSPSSVTGNALWK 16 1 Q9NYB0;A0A590UJT3 Q9NYB0 TERF2IP Telomeric repeat-binding factor 2-interacting protein 1 1 ENARS(0.823)PS(0.088)S(0.088)VTGNALWK 84.46799999999999 0.0088784 0.0 13314.0 10211.0 15466.0 32212.0 23849.0 17131.0 9515.8 14819.0 15961.0 15719.0 True False 17547.575051596363 13511.506063011848 15260.91073469512 24786.021070438954 20537.978013705535 16059.795861880519 10362.68776545276 12529.064056743058 16804.665874972696 15168.68259449124 1.1568292066424448 0.8907501346174108 1.0060801681114597 1.634025955519724 1.3539724287700663 1.0587469123859774 0.683163333460227 0.8259823474250293 1.1078526938836197 1.0 13.88880817199488 -7.003093309557954 24.012052120793246 0.8870633871250679 1.203427510575218 0.3105210147759949 0.21301925546404848 100.03255032601267 776520.03290916 0.08394386873921018 0.07253624660715363 9.929026971831791e-08 7.003093309557954 0.31636412345014997 ENAS(ph)PAPGTTAEEAMSR ddPTM_PC-9_AZD4547_30min_R2 3 ENASPAPGTTAEEAMSR 17 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 ENAS(0.741)PAPGT(0.015)T(0.243)AEEAMSR;ENAS(0.997)PAPGT(0.001)T(0.002)AEEAMSR;ENAS(0.992)PAPGTT(0.008)AEEAMSR 234.51 2.9751999999999997e-37 118390000.0 158615.0 198225.0 230698.0 179715.0 181870.0 208309.0 208076.0 271279.0 213671.0 199578.0 True False 209051.27060304643 262297.35474885156 227638.7937846048 138284.4833190717 156620.48980471396 195283.40529989297 226594.36090337601 229359.0639212634 224965.21284200813 192590.8349668151 1.08546842656904 1.3619410019902942 1.1819814469563348 0.7180221392305568 0.8132291956245005 1.0139807812430006 1.176558380581402 1.1909137003366943 1.1680992653714357 1.0 17.555179524126316 -5.54276890067909 24.999006088737197 1.0129652118483046 1.235769012307006 0.2516024866142923 0.15749908615329908 329.6904314761641 414370.6865620987 0.0480687122998143 0.08326921188663346 2.8657024786264497e-06 5.54276890067909 0.2228038004587014 ENAS(ph)PAPGTTAEEAMSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENASPAPGTTAEEAMSR 17 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 ENAS(0.809)PAPGT(0.028)T(0.164)AEEAMSR 118.05 0.00010382 61245000.0 15963.0 26664.0 22323.0 13168.0 19406.0 14012.0 15916.0 11584.0 13547.0 12871.0 True False 18665.22061637859 29311.025703762996 22855.26498044894 12430.239651232008 15603.533607136607 13277.186053283753 14408.321258138702 11279.93227426255 13745.099246593942 15204.410413220052 1.2276188361864662 1.9277975868289778 1.503199687412842 0.8175417075313927 1.0262504880537506 0.8732457025587391 0.9476409059315342 0.7418855429247545 0.9040205356889566 1.0 13.892202253108868 -5.709389536748597 5.499220120106381 0.8963647763416045 1.6047509289482222 0.739909471113745 0.1767040139987492 0.08494071458625393 5.498474658014649 0.045607266035310595 0.07885034258130698 1.9525873134939534e-06 5.709389536748597 0.7083861526066177 ENAS(ph)PAPGTTAEEAMSR ddPTM_PC-9_Lapatinib_30min_R1 9 ENASPAPGTTAEEAMSR 17 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 ENAS(0.671)PAPGT(0.017)T(0.311)AEEAMS(0.001)R;ENAS(0.434)PAPGT(0.283)T(0.283)AEEAMS(0.001)R;ENAS(0.32)PAPGT(0.192)T(0.192)AEEAMS(0.295)R;ENAS(0.725)PAPGT(0.011)T(0.132)AEEAMS(0.132)R;ENAS(0.841)PAPGT(0.01)T(0.15)AEEAMSR;ENAS(1)PAPGTTAEEAMSR;ENAS(0.784)PAPGT(0.003)T(0.213)AEEAMSR;ENAS(0.9)PAPGT(0.096)T(0.004)AEEAMSR;ENAS(0.971)PAPGT(0.002)T(0.027)AEEAMSR 201.14 9.8385e-13 275403100.0 299430.2 467391.0 441685.0 387601.0 482808.0 469925.0 509185.0 513601.0 442739.0 373378.3 True False 295160.27043922624 466308.78485591715 405371.3642534054 416106.47053903266 454410.18267704913 449827.40319867915 535548.1078386611 537464.7774526321 392873.07157164294 437916.24165968865 0.6740107864476051 1.064835556426548 0.9256824152423779 0.9501964781255939 1.0376646021505138 1.0271996340986294 1.222946437905456 1.2273232328987334 0.8971420426944351 1.0 18.74029543262509 -3.900633007090825 0.6285977015360273 1.0812917524653147 7.787443018292206e-20 0.4270769559713552 0.11541985335987129 9.53856065925124 1.2521959038191637 0.052981191138682944 9.552891700884716 0.00012570917982910893 3.900633007090825 -1.0812917524653147 ENASPAPGTT(ph)AEEAMSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ENASPAPGTTAEEAMSR 17 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 ENAS(0.473)PAPGT(0.034)T(0.49)AEEAMS(0.003)R;ENAS(0.442)PAPGT(0.022)T(0.494)AEEAMS(0.042)R 88.637 0.010283 137547000.0 32590.0 51261.0 44552.0 37870.0 46998.0 27156.0 41536.0 25041.0 26168.0 25931.0 True False 38106.84331815939 56349.85330785313 45614.288644400884 35748.26667619653 37789.079277965924 25731.891554594178 37601.40938540143 24383.70028313265 26550.657495007763 30632.08503031694 1.2440172871172364 1.8395696294288493 1.48910165923266 1.1670203527058653 1.233643718361503 0.840030690993676 1.2275171392409907 0.7960183010395737 0.8667597216686446 1.0 14.902755949572226 -6.089317642236785 1.2352333744016244 0.9497023862153865 1.5737780720461765 0.6165873441268619 0.18909446234188731 0.29026397279195837 0.9022013828958161 0.07092481833637759 0.12255580225973599 8.141086285665876e-07 6.089317642236785 0.62407568583079 ENASPAPGTT(ph)AEEAMSR ddPTM_PC-9_Lapatinib_30min_R1 2 ENASPAPGTTAEEAMSR 17 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 ENAS(0.024)PAPGT(0.064)T(0.911)AEEAMS(0.001)R;ENAS(0.242)PAPGT(0.051)T(0.7)AEEAMS(0.008)R 90.87200000000001 0.0088325 5781400.0 22158.0 34345.0 35433.0 30423.0 37592.0 37318.0 38946.0 38972.0 36525.0 26786.0 True False 21842.02285672046 34265.47626265051 32519.835515335395 32660.408908152913 35380.91246871563 35721.996132506865 40962.433315758455 40782.78139428078 32411.169874698797 31415.924409898525 0.6952532280042818 1.0907040587306147 1.0351385842107848 1.0396131745804136 1.126209498313149 1.137066529267927 1.3038748368917012 1.2981563382368893 1.031679649206397 1.0 14.93920841139075 -4.2256837697468335 0.9205314651014859 1.1565168989946444 1.9935767640258635e-37 0.5739063319375991 0.10594980956439584 3.9135502021205255 1.278365985328998 0.036731111190497524 5.7885573131712045 5.94725048292295e-05 4.2256837697468335 -1.1565168989946444 ENCQAELS(ph)PAASK ddPTM_PC-9_AZD4547_30min_R2 1 ENCQAELSPAASK 13 0 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 ENCQAELS(0.716)PAAS(0.284)K 86.54799999999999 0.032088 0.0 5522.3 9909.2 8011.1 8516.5 5842.1 10656.0 8714.6 7440.3 8246.4 7798.6 True False 7278.276529024382 13112.155115032512 7904.867579640244 6553.152503613354 5031.025256986421 9989.678635467786 9490.182517582827 6290.572596085116 8682.287868640733 7525.573387709097 0.9671391339976029 1.7423463222679514 1.05040070336044 0.8707844792685275 0.6685238450007255 1.3274308973962183 1.261057733232974 0.8358927980635992 1.1537044981610043 1.0 12.87758579239353 -5.484891297743409 24.689035430708127 1.0140873671287232 1.365150637876764 0.21556099819768582 0.25519851848530767 658.0989342833299 427714.26734729245 0.06610926687066007 0.13756150743959686 3.2742263726393785e-06 5.484891297743409 0.3510632707480408 ENDPLRT(ph)PEALPEEK ddPTM_PC-9_AZD4547_30min_R2 3 ENDPLRTPEALPEEK 15 1 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 ENDPLRT(1)PEALPEEK;ENDPLRT(1)PEALPEEK;ENDPLRT(1)PEALPEEK 75.608 0.010667 12334600.0 60943.0 68635.0 84270.0 103346.0 91940.0 97558.0 71338.6 97961.0 80002.0 85458.0 True False 80321.60630685282 90819.92151942215 83152.52473896016 79521.17637978353 79175.71799991968 91457.68283774077 77687.59719881968 82823.37836983649 84230.74239267998 82466.14143139093 0.9739949622073406 1.1012995144799067 1.008323213571721 0.9642887977963961 0.9600997042621574 1.1090331286304997 0.9420544704817208 1.004331922559306 1.0213978844003164 1.0 16.331514285387165 -5.498819719476535 24.521349060103418 0.9996826472036208 1.0419382738459342 0.07431754787894329 0.051702405142576645 1363.715259096733 1389916.934831632 0.0131356165871703 0.027095370899887228 3.1708834592655154e-06 5.498819719476535 0.042255626642313415 ENDPLRT(ph)PEALPEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ENDPLRTPEALPEEK 15 1 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 ENDPLRT(1)PEALPEEK;ENDPLRT(1)PEALPEEK 76.76100000000001 0.0098148 7936500.0 41522.0 38865.0 39256.0 46639.0 45864.0 52744.0 54074.0 44052.0 40748.0 40748.0 True False 48550.85450311799 42723.26035016312 40192.01191920904 44025.96803567815 36877.27843747879 49978.01178949458 48951.71925814224 42895.68167695215 41343.8624123577 48135.289839009485 1.0086332639836257 0.8875662843841362 0.8349801580842855 0.9146297484221008 0.7661173031432117 1.0382821409541347 1.0169611406073038 0.8911482993125952 0.8589095973169374 1.0 15.554807356875736 -6.778867419361901 24.999752623060033 0.9577507702737409 0.881830863096613 0.20786874798686672 0.07665103012796713 443.77183731631624 636566.9789522674 0.028012286912601873 0.024760717219617222 1.6639205315100163e-07 6.778867419361901 -0.07591990717712793 ENDPLRT(ph)PEALPEEK ddPTM_PC-9_Lapatinib_30min_R1 3 ENDPLRTPEALPEEK 15 1 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 ENDPLRT(1)PEALPEEK;ENDPLRT(1)PEALPEEK;ENDPLRT(1)PEALPEEK 108.34 0.00053697 10974200.0 75503.0 68277.0 76849.0 63502.0 79578.0 82748.0 87705.0 83380.0 83892.0 72758.0 True False 74426.31337444541 68118.9088014263 70530.77186571866 68172.14891646209 74897.37849636757 79209.06093500934 92245.93575613917 87254.139193655 74443.19953807608 85334.1233560588 0.8721752851892521 0.7982610721527942 0.8265248307693656 0.7988849739747377 0.87769552847993 0.9282225892742523 1.0809970516863536 1.0224999772902674 0.8723731680872836 1.0 16.380835140463496 -6.779739124594321 2.440506750025348 0.995875505523059 0.8242945950111766 0.6663436798982771 0.05355740998009984 0.16973648872972658 2.072913945010839 0.020764915271944847 0.018988736186662438 1.6605841005503916e-07 6.779739124594321 -0.1715809105118824 ENDTVTIS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 ENDTVTISPK 10 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 ENDTVTIS(1)PK;ENDTVT(0.001)IS(0.998)PK 113.54 0.0012924000000000002 11513300.0 73311.0 101734.0 70405.0 56992.0 65433.0 86621.0 95288.0 85370.0 84304.0 75925.0 True False 96622.3730364713 134617.52598319927 69471.38369819021 43853.37491762251 56348.75740579458 81204.57517669456 103768.44740268406 72178.02810744019 88760.13732997283 73266.88885977141 1.3187727026515474 1.8373582948342386 0.9481961740064386 0.5985428834238524 0.7690889879825913 1.1083393390992133 1.4163075437977293 0.9851384333458564 1.211463168578846 1.0 16.16087373520395 -5.274626163139307 24.777991917322428 0.9995945039574451 1.5780654966285868 0.4748360088023077 0.24117529951703706 546.0468017366684 1026023.499055688 0.06847645036357082 0.14392495887522222 5.313416216184877e-06 5.274626163139307 0.5784709926711417 ENDTVTIS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENDTVTISPK 10 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 ENDTVT(0.004)IS(0.996)PK 108.97 0.0019510999999999999 5232000.0 45531.0 56751.0 37899.0 35712.0 33664.0 27233.0 37273.0 22839.0 27038.0 26131.0 True False 53238.49902175871 62384.86422570713 38802.65589275787 33711.17241986613 27067.780859046008 25804.85353904342 33742.231606848676 22239.500449920793 27433.37959912945 30868.343447117826 1.7246956939222984 2.0209981249101334 1.2570371960268205 1.0920952877700907 0.876878310798156 0.8359649614256451 1.0931014702701574 0.7204630364444546 0.8887221190254996 1.0 14.913840442199472 -5.50107522775496 2.101196404324298 0.907458482177652 1.8902244345332475 0.8854222741843581 0.13349825906812754 0.09262367190031222 0.7976179209306055 0.037198616965275905 0.09667696816509869 3.1544581661442795e-06 5.50107522775496 0.9827659523555955 ENES(ph)LDLQALK ddPTM_PC-9_AZD4547_30min_R2 1 ENESLDLQALK 11 0 Q9C0G6-3;Q9C0G6-4;Q9C0G6 Q9C0G6-3 DNAH6 Dynein heavy chain 6, axonemal 1 ENES(1)LDLQALK 64.945 0.045924 4066400.0 27574.0 22530.0 34818.0 58024.0 47048.0 29566.0 30120.0 39689.0 32659.0 42088.0 True False 36341.958425170356 29812.381901836936 34356.29057032293 44647.46326186358 40516.19730759437 27717.23334611868 32800.621649828405 33555.97701248903 34385.288065330045 40614.51193059019 0.8948022935072669 0.7340327504805674 0.8459116935601123 1.0992982837800849 0.9975793228005831 0.6824465450548111 0.8076084160726676 0.8262065802941537 0.8466256623763981 1.0 15.309707686996555 -6.739364400930225 24.999658087751136 0.820154663211616 0.9107841635148626 0.10808402653027216 0.114445873697263 554.5737914993443 628047.0613630288 0.04050040944552532 0.040468781574335366 1.8223659786807093e-07 6.739364400930225 0.09062950030324657 ENFQNWLK ddPTM_PC-9_AZD4547_30min_R2 1 ENFQNWLK 8 0 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 0 107.01 0.017586 7042100.0 25950.0 22922.0 29871.0 56838.0 47420.0 34927.0 27277.0 39021.0 27565.0 37366.0 False True 34201.5602064688 30331.08823585913 29474.89102263533 43734.87723834625 40836.55152878178 32743.009168635825 29704.600157449182 32991.20106337614 29022.029624937153 36057.82771332524 0.948519707797859 0.8411790215706815 0.8174339080261018 1.2129093739660846 1.1325294428008639 0.9080693775830423 0.8238044841085029 0.9149525402825134 0.8048745990932783 1.0 15.138024864461336 -6.983457165169298 24.950096600448724 0.8769800534923575 0.9884917829363361 0.14497603897599887 0.12176714268228765 492.5537235827385 742872.6764048995 0.04722763087500009 0.04164043083359859 1.0388260576593334e-07 6.983457165169298 0.11151172944397858 ENFQNWLK ddPTM_PC-9_Lapatinib_30min_R1 1 ENFQNWLK 8 0 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 0 140.5 0.011398 14175000.0 42794.0 60651.0 68321.0 57594.0 52674.0 58977.0 57688.0 45459.0 62252.0 67862.0 False True 42183.749712541525 60510.56633588632 62703.91110668658 61829.65488795182 49575.818881068495 56454.69119210189 60674.80237044815 47571.19109623853 55240.524217378515 79591.8562795691 0.5300008277777776 0.7602607749634699 0.7878181768551417 0.776833934752986 0.6228755201654268 0.7093023561833119 0.7623242528397107 0.597689177258828 0.6940474415289963 1.0 16.28033320345751 -10.517616352513382 4.531490258122098 1.0000081019488534 0.6982518111593568 0.5596090957621751 0.0814802348114059 21520997.27416879 12487592.569463395 1643.564277430705 0.01976978848536468 3.0365724500881404e-11 10.517616352513382 -0.3017562907894966 ENFS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 1 ENFSPER 7 0 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;H3BSK8 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 ENFS(1)PER 92.23899999999999 0.014719999999999999 123740000.0 229270.0 364030.0 366000.0 328410.0 351210.0 346300.0 317850.0 310940.0 368140.0 279590.0 True False 226000.56775703092 363187.1109009366 335908.8928008565 352562.3669436448 330552.51830542705 331489.5562647283 334306.71774800576 325387.40754227823 326676.19651393883 327916.7589697434 0.6892010291486316 1.1075588574429878 1.0243724470082682 1.075158122602009 1.0080378915184596 1.010895439764073 1.01948652700258 0.9922866051878168 0.9962168372860778 1.0 18.322970110430333 -4.752856473506074 24.99997568056197 1.0260086022183743 0.6892003970374584 0.8919758474826379 0.03516232958209795 99.55556867543109 289959.9753066985 0.008883350379510527 0.10156063536249942 1.766621560788527e-05 4.752856473506074 -0.3368082051809159 ENFT(ph)AGSDCVTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ENFTAGSDCVTLK 13 0 Q1W6H9 Q1W6H9 FAM110C Protein FAM110C 1 ENFT(0.98)AGS(0.01)DCVT(0.01)LK;ENFT(0.711)AGS(0.287)DCVT(0.002)LK 177.88 0.00032251 22478000.0 49583.0 62836.0 55885.0 52357.0 60979.0 47604.0 49504.0 39041.0 42010.0 39703.0 True False 57976.42259111071 69073.9428113431 57217.51034504271 49423.60703368423 49030.60269141417 45107.56243794747 44814.62274207704 38016.21511735879 42624.316774888255 46900.83961122491 1.2361489276459574 1.4727655919151488 1.2199677195405407 1.0537893872129218 1.0454099137210229 0.9617644974345352 0.9555185602978294 0.8105657688111039 0.9088177765731694 1.0 15.517326129413942 -5.881281638448839 1.073534558497326 0.9151290013450957 1.3779573746370577 0.8129235844895952 0.07929060075720094 0.217564737927581 0.49841800690832183 0.03082782741959917 0.07432005199922762 1.3143721899974754e-06 5.881281638448839 0.462828373291962 ENFTAGS(ph)DCVTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENFTAGSDCVTLK 13 0 Q1W6H9 Q1W6H9 FAM110C Protein FAM110C 1 ENFT(0.127)AGS(0.746)DCVT(0.127)LK 70.977 0.026962 7123400.0 17870.0 19783.0 18105.0 18683.0 19885.0 16819.0 21463.0 17347.0 16566.0 11985.0 True False 20895.038051411728 21746.925498707744 18536.691863594857 17636.252081103252 15988.676995666889 15936.982031842661 19429.869261336455 16891.659630665778 16808.246410207077 14157.785626792194 1.4758690802515018 1.5360400328109123 1.309293158706685 1.245692832622667 1.1293204613445986 1.1256691160574939 1.3723805242938112 1.193100395495465 1.1872087099835127 1.0 13.789308015375292 -1.5228787459723954 0.328482624607191 1.1360789630104986 5.448927521425156 0.6344833705459514 0.09568662753720521 39.77670585602312 0.566539727729721 0.09191818742996948 103.98256214571177 0.02999999995219434 1.5228787459723954 4.312848558414657 ENGITQALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENGITQALR 9 0 E9PPY4;F2Z3C6;F8W895;A0A0A0MRK1;E9PAV9;Q5T3I0;Q5T3I0-3 E9PPY4 GPATCH4 G patch domain-containing protein 4 0 85.161 0.039322 0.0 10690.0 13689.0 17602.0 17467.0 24425.0 19830.0 20616.0 20631.0 17802.0 16900.0 False True 12499.605862875853 15047.9534525507 18021.69843595674 16488.380618778046 19639.096586329575 18790.079891280107 18663.103233085403 20089.45811035141 18062.32057192481 19963.836219673605 0.6261124227495898 0.7537606142912309 0.9027172051330014 0.8259124367354492 0.9837336056171403 0.9412058726850902 0.9348455390900082 1.0062924725135747 0.9047519912092385 1.0 14.285101352895706 -4.0700746775672725 0.6034188492560718 0.9647083790734938 2.2585647217745626e-12 0.8611412999646538 0.04276163587144594 2.549169071474121 0.37401358915531113 0.01920440773200526 2.0694147861019974 8.509916963620552e-05 4.0700746775672725 -0.9647083790712353 ENGSFS(ph)GK ddPTM_PC-9_AZD4547_30min_R2 2 ENGSFSGK 8 0 H0Y897;H7C556;D3YTG3;Q7Z7G0-4;Q7Z7G0-2;Q7Z7G0-3;Q7Z7G0 H0Y897 ABI3BP Target of Nesh-SH3 1 ENGS(0.012)FS(0.988)GK;ENGS(0.023)FS(0.977)GK 80.916 0.010553 3470500.0 19391.2 12561.2 48646.0 66135.0 51949.0 23014.0 19094.2 54826.0 20618.0 28576.0 True False 25557.198237983735 16621.36225234594 48000.92225526826 50888.59752556439 44736.778055012335 21574.93094187836 20793.546809633255 46353.901476145154 21707.825387518747 27575.56293785746 0.9268060382149883 0.6027569515009644 1.7407050714953707 1.8454237050479698 1.6223341715934614 0.7823931279480407 0.7540570198509555 1.6809775227655503 0.7872124110915932 1.0 14.751102717382988 -6.763663537000537 24.99984453756635 1.0280597068568154 1.3557201804403458 0.13937545596156853 0.4278496513757178 147.7202495562667 1660377.409473963 0.16182078407141387 0.1496363562416543 1.723203083175489e-07 6.763663537000537 0.32766047358353045 ENGSFS(ph)GK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENGSFSGK 8 0 H0Y897;H7C556;D3YTG3;Q7Z7G0-4;Q7Z7G0-2;Q7Z7G0-3;Q7Z7G0 H0Y897 ABI3BP Target of Nesh-SH3 1 ENGS(0.011)FS(0.989)GK 58.676 0.043481 1821100.0 8940.5 8005.6 37819.0 11617.0 17051.0 15366.0 8916.2 16042.0 12623.0 7541.2 True False 10453.950067075919 8800.343060832778 38720.748389356195 10966.137152822164 13709.978951627665 14560.179909702978 8071.592988302102 15620.91449790399 12807.587494630194 8908.359863893644 1.1734988512808835 0.9878746700053432 4.346563113856093 1.2309939562801981 1.5390014728968686 1.6344400239955115 0.9060694798620529 1.753511840178001 1.4377043238386067 1.0 13.120944123363484 ENGVYLIDVK ddPTM_PC-9_Lapatinib_30min_R1 3 ENGVYLIDVK 10 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ;; 124.42 0.0019039999999999999 17294900.0 109523.0 109324.0 102385.0 93396.0 99461.0 91004.0 111867.0 99440.0 99077.0 111936.0 False True 107961.18193594161 109070.86699484667 93967.30051752932 100264.65339992245 93610.89952784959 87111.97106068532 117658.92589056512 104060.34542356741 87917.90493293728 131283.98845465548 0.8223484311129884 0.8308009855483552 0.7157559853537275 0.7637233952147418 0.713041252248229 0.6635384260188983 0.8962168751538474 0.7926354664301587 0.6696772848526268 1.0 17.002331448659646 -10.435294700356604 5.549678083941207 1.0000002172574378 0.764086079411215 0.5021109982809793 0.07076959093761263 1.946839729482601e-07 3.8132554120149815e-08 0.07013231089917804 0.01700956827136685 3.6703315731530107e-11 10.435294700356604 -0.23591413784622284 ENHGQADHS(ph)PSMTATHFPR ddPTM_PC-9_AZD4547_30min_R2 3 ENHGQADHSPSMTATHFPR 19 0 Q9Y3L3;Q6ZT62-2;Q6ZT62;Q9Y3L3-2 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 ENHGQADHS(0.989)PS(0.01)MT(0.001)ATHFPR;ENHGQADHS(0.93)PS(0.061)MT(0.009)AT(0.001)HFPR;ENHGQADHS(0.958)PS(0.028)MT(0.013)AT(0.001)HFPR 58.01 0.013119 50038300.0 36230.5 34820.7 72434.0 82181.0 72460.0 77257.0 62654.0 92498.0 62553.0 71055.0 True False 47751.0453587849 46075.81031909867 71473.4778324651 63235.44013379305 62400.17975064377 72426.10757698343 68230.08462311924 78204.55949258505 65859.42387551948 68567.38607745884 0.6964104669943485 0.671978515661192 1.042383003367276 0.9222378706745153 0.9100562719446804 1.0562763395291968 0.9950807304516676 1.1405503981767562 0.9605065562966009 1.0 16.06523490445168 -5.2585605732611915 24.982001401490958 1.0037669724046439 0.6841944556229262 0.8004191189000909 0.0637545295091274 101.42584243555356 880151.9966302111 0.017171231144245742 0.04145531486428698 5.513652952953357e-06 5.2585605732611915 -0.3195725167817176 ENHGQADHS(ph)PSMTATHFPR ddPTM_PC-9_Lapatinib_30min_R1 2 ENHGQADHSPSMTATHFPR 19 0 Q9Y3L3;Q6ZT62-2;Q6ZT62;Q9Y3L3-2 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 ENHGQADHS(0.994)PS(0.006)MTATHFPR;ENHGQADHS(0.859)PS(0.126)MT(0.013)AT(0.002)HFPR 57.00899999999999 0.023646 33456000.0 25955.5 36325.0 49146.0 34211.0 44518.0 48478.0 36847.0 41778.0 53338.0 37676.0 True False 25585.369810344237 36240.89169430137 45105.405589046124 36726.99106455048 41899.53876575554 46404.708947737476 38754.75736624435 43719.15839808736 47330.512765959866 44188.246399885604 0.5790084896967188 0.8201477688509311 1.0207557272325452 0.8311484174363063 0.9482055111800954 1.0501595498448566 0.8770376858934297 0.9893843263759963 1.0711109089425734 1.0 15.43137505876866 -4.835894622924728 2.290177746216885 0.9670039878299258 0.5072260600045638 0.7452625905602255 0.07100295021307247 0.2622917049590468 1.8240434687787348 0.018834827591238796 0.23591845566745354 1.4591682694511272e-05 4.835894622924728 -0.459777927825362 ENHGQADHSPS(ph)MTATHFPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENHGQADHSPSMTATHFPR 19 0 Q9Y3L3;Q6ZT62-2;Q6ZT62;Q9Y3L3-2 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 ENHGQADHS(0.133)PS(0.768)MT(0.086)AT(0.013)HFPR 52.86600000000001 0.016649 45744000.0 21468.0 16121.0 26259.0 28260.0 39734.0 22992.0 24492.0 22679.0 23580.0 16537.0 True False 25102.10838767247 17721.386340022636 26885.114147812073 26676.683820156177 31948.40793290562 21786.25904489723 22171.940453275503 22083.700280386765 23924.812891022753 19535.027193180034 1.2849794443304376 0.9071595429470113 1.3762516879013131 1.3655821185377925 1.6354422042503876 1.1152407841286822 1.134983854080124 1.1304668307857033 1.2247135698574947 1.0 14.253775643335109 ENIKPNET(ph)SPSFSK ddPTM_PC-9_AZD4547_30min_R2 1 ENIKPNETSPSFSK 14 1 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;F8WB06 Q99700;F8WB06 ATXN2 Ataxin-2 1 ENIKPNET(0.691)S(0.308)PS(0.001)FSK 166.3 0.0045673 7578700.0 30533.0 36451.0 29768.0 23834.0 30556.0 37844.0 36130.0 42589.0 34400.0 32436.0 True False 40241.85887414691 48233.07291184459 29373.256869934343 18339.439531629272 26313.82683495269 35477.60869750781 39345.50000691571 36007.84864785951 36218.31377100812 31300.42551275004 1.2856649139723237 1.5409717958050486 0.93842995386658 0.5859166203398357 0.8406859141334648 1.1334545175130675 1.2570276397964162 1.1503948607085845 1.1571188946378639 1.0 14.933894649517617 -6.9761516359977 24.911104939384288 1.159607354141382 1.0307233135276406 0.03832932662770083 0.24553824285725484 838.1141118153098 875459.551860128 0.09954116227334077 0.08778301807537787 1.0564485807307387e-07 6.9761516359977 -0.12888404061374148 ENIKPNET(ph)SPSFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENIKPNETSPSFSK 14 1 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;F8WB06 Q99700;F8WB06 ATXN2 Ataxin-2 1 ENIKPNET(0.981)S(0.019)PSFSK 116.58 0.0014675 7222100.0 28241.0 41613.0 31910.0 26507.0 32589.0 21487.0 34047.0 23720.0 20405.0 19746.0 True False 33021.643514824784 45744.06362926381 32670.855419348885 25021.898726853495 26203.41939209395 20360.183894298312 30821.821681066103 23097.375133417434 20703.384522532604 23325.79349075001 1.4156707478319965 1.9610935699745393 1.4006321127855617 1.0727137208333808 1.1233666885752496 0.8728613627816036 1.3213621947432868 0.9902074775109727 0.887574715550091 1.0 14.509638538684303 -5.598955637346107 3.265537859789014 1.0449308157517636 1.692385495491812 0.6996049233114658 0.17256081435091333 0.12078938957350771 2.5723948299417625 0.04617497383323676 0.089698793132088 2.5179341185350482e-06 5.598955637346107 0.6474546797400484 ENIKPNETS(ph)PSFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENIKPNETSPSFSK 14 1 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;F8WB06 Q99700;F8WB06 ATXN2 Ataxin-2 1 ENIKPNET(0.176)S(0.728)PS(0.092)FS(0.004)K 51.235 0.045894 6930000.0 21594.0 36730.0 34203.0 31593.0 31565.0 32826.0 28720.0 21355.0 24510.0 18686.0 True False 25249.43769905903 40376.31165988654 35018.52923559982 29822.946635887954 25380.06484124844 31104.546773129638 25999.433685206288 20794.453877492808 24868.412381635608 22073.623881705378 1.1438736944315595 1.8291655179170843 1.5864422363662352 1.351067083307749 1.1497914876715571 1.4091273340445511 1.1778507156115232 0.9420498414275896 1.1266121283441162 1.0 14.430035879442551 -6.801426255890619 0.6811475016813748 1.008196830149925 1.5457973004192387 0.4741841541941869 0.1888916094124474 0.6277491370705218 0.6357571827341182 0.14563579141493116 0.14508341129249644 1.5796968207832722e-07 6.801426255890619 0.5376004702693138 ENIKPNETS(ph)PSFSK ddPTM_PC-9_Lapatinib_30min_R1 2 ENIKPNETSPSFSK 14 1 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;F8WB06 Q99700;F8WB06 ATXN2 Ataxin-2 1 ENIKPNET(0.381)S(0.617)PS(0.001)FSK;ENIKPNET(0.274)S(0.725)PS(0.001)FSK 157.37 0.00054086 23219000.0 70053.0 164071.0 154456.0 139036.0 204057.0 183637.0 205180.0 201902.0 166552.0 168737.0 True False 69054.03137385332 163691.1036799923 141757.22389740162 149261.17125049935 192054.76845149777 175783.27358875517 215803.21644654975 211283.1039994883 147793.15988968743 197902.96562208008 0.34892873462907287 0.8271280986894379 0.716296612593994 0.7542139188329892 0.9704491686003829 0.8882296080617348 1.0904496340830605 1.0676095900602076 0.7467960847636642 1.0 17.594433706105768 -4.541975498259023 0.5988426799250163 0.9746580191157376 6.554201550012844e-14 0.646762000458311 0.12354939921963905 3.135133420401717 0.6948523725905149 0.061505542042817066 2.2484192699292023 2.8709425484077867e-05 4.541975498259023 -0.9746580191156721 ENIKPNETSPS(ph)FSK ddPTM_PC-9_AZD4547_30min_R2 1 ENIKPNETSPSFSK 14 1 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;F8WB06 Q99700;F8WB06 ATXN2 Ataxin-2 1 ENIKPNET(0.018)S(0.071)PS(0.87)FS(0.041)K 136.17 0.00024713 8200100.0 25854.0 30241.0 30072.0 24864.0 22891.0 29075.0 34343.0 35611.0 33508.0 23916.0 True False 34075.03420339287 40015.811855013366 29673.225631304245 19131.98894497065 19712.97977742183 27256.935653737437 37399.46046879342 30108.138209371537 35279.16447206222 23078.70811946384 1.4764706077570728 1.7338843945630265 1.2857403229723592 0.8289887304755739 0.8541630526015682 1.181042522512333 1.62051793693131 1.3045850770121443 1.5286455502380962 1.0 14.494274847821979 -7.1451401466768205 17.673044334034703 1.3907152175179591 1.2174139428885988 0.04613353441637491 0.2923378395643447 8.035866315470992 1189.494688980034 0.12455884673916211 0.09648322422009632 7.15912348269688e-08 7.1451401466768205 -0.1733012746293603 ENILEEFSK ddPTM_PC-9_Lapatinib_30min_R1 1 ENILEEFSK 9 0 O43390-4;O43390;O43390-2;B4DT28;O43390-3 O43390-4 HNRNPR Heterogeneous nuclear ribonucleoprotein R 0 94.363 0.026592 1014900.0 9966.8 7196.5 10369.0 7690.4 8432.7 9230.8 8272.2 9499.5 10552.0 7914.3 False True 9824.671604312727 7179.836946401643 9516.500845497487 8255.977670422344 7936.7051653260805 8836.020202045782 8700.494039814543 9940.881449629736 9363.522642513937 9282.276209858133 1.0584334469468328 0.7734996011836387 1.025233534355571 0.889434604591294 0.8550386764937026 0.9519238602985752 0.9373233292254635 1.070952988780073 1.0087528566074684 1.0 13.180262912644626 -7.655069345876096 5.876090781867146 1.0292576931002968 0.9205437571591748 0.25230657301268045 0.07806393347051331 0.25815755815474045 12.422245339735904 0.03527154180752616 0.0199521377417335 2.212741362404594e-08 7.655069345876096 -0.108713935941122 ENIPEDS(ph)S(ph)MVS(ph)KR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENIPEDSSMVSKR 13 1 O94768 O94768 STK17B Serine/threonine-protein kinase 17B 3 ENIPEDS(1)S(1)MVS(1)KR 59.68 0.033262 0.0 2848.0 1314.4 989.23 3061.0 2706.4 5140.8 4818.9 4845.4 3673.9 3682.7 True False 3330.1101494359627 1444.8849454330216 1012.8169948756668 2889.502093895898 2176.1003480549575 4871.207398138818 4362.418906185261 4718.21338412567 3727.623837164058 4350.344357762842 0.7654819654663997 0.3321311663189926 0.23281306296325155 0.6642007749891826 0.5002133553340163 1.1197291518880652 1.0027755385388912 1.0845608981979542 0.8568571889056117 1.0 12.08691388874383 -6.753553687150575 24.867375475769112 1.0174440571390566 0.4840924314002115 0.7334785045500569 0.15472138829959448 84.94740779750178 267879.5963032063 0.05225996219597086 0.05134471948237121 1.7637877129154703e-07 6.753553687150575 -0.5333516257388451 ENLLDFIK ddPTM_PC-9_Lapatinib_30min_R1 1 ENLLDFIK 8 0 P07237;H7BZ94;I3L398;I3L312;H0Y3Z3;I3NI03;I3L4M2 P07237 P4HB Protein disulfide-isomerase 0 118.18 0.016191999999999998 4791700.0 57593.0 49503.0 56358.0 50037.0 54670.0 49650.0 48191.0 45375.0 43957.0 48854.0 False True 56771.71325873731 49388.37884495527 51724.46278817124 53716.8878985388 51454.41808535543 47526.585239802946 50686.09417962604 47483.28814958147 39006.0997722693 57298.348806136855 0.9908088878934128 0.861951170915166 0.9027216990698231 0.9374945180407281 0.898008741219511 0.8294581995827545 0.8845995606455832 0.8287025566868664 0.6807543425769995 1.0 15.80620594429914 -6.668304351959371 4.0108911917540055 0.8362688797717269 0.9175007252878425 0.17691451236128108 0.07910984219646365 0.38316783202852034 11.543939012170775 0.02643851235913808 0.026048594009428425 2.1463258098073236e-07 6.668304351959371 0.08123184551611562 ENLLLSDSPS(ph)CR ddPTM_PC-9_AZD4547_30min_R2 1 ENLLLSDSPSCR 12 0 E9PF63;O75116;D6REE7 E9PF63 ROCK2 Rho-associated protein kinase 2 1 ENLLLS(0.003)DS(0.2)PS(0.796)CR 115.1 0.00073827 2292100.0 11873.0 13717.0 17494.0 16874.0 16374.0 17917.0 15869.0 17885.0 14969.0 15220.0 True False 15648.367026258346 18150.751999445063 17262.01812962346 12983.960000701205 14100.752735813434 16796.647157627303 17281.310257673547 15121.284206414039 15760.23078018083 14687.152432607449 1.065445946589134 1.235825125580365 1.175314153565906 0.8840352178734846 0.9600739694447421 1.1436285716172248 1.1766276912403197 1.0295586074835554 1.0730623824119236 1.0 13.842267090652673 ENLLLSDSPS(ph)CR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENLLLSDSPSCR 12 0 E9PF63;O75116;D6REE7 E9PF63 ROCK2 Rho-associated protein kinase 2 1 ENLLLSDS(0.333)PS(0.667)CR 107.11 0.0024941 0.0 10899.0 13078.0 11161.0 15088.0 11093.0 13731.0 12665.0 9824.4 10584.0 8577.3 True False 12743.985434937691 14376.29741050902 11427.12056832821 14242.668275955986 8919.4062817668 13010.922187955983 11465.279513340449 9566.519909812234 10738.77097703922 10132.296592130555 1.257758822894659 1.4188587236653387 1.1277917562345445 1.4056702887100474 0.8802946302118939 1.2841039609974672 1.1315578269042361 0.9441610618901797 1.0598555697017096 1.0 13.306673592835008 -6.175354137165539 0.4345514654825257 0.9920897295842724 1.3953122915524525 0.3778057016744746 0.13973173198902936 1.806549353185251 0.5983059194821583 0.12318365046393827 0.33385686754442123 6.677991513872648e-07 6.175354137165539 0.40322256196818007 ENLPENVTAS(ph)ESDAEVER ddPTM_PC-9_Lapatinib_30min_R1 1 ENLPENVTASESDAEVER 18 0 Q9NX02;A0A0G2JPQ2;J3KN39;A0A0G2JLX3;A0A0G2JMG8;A0A0G2JPB6;A0A0G2JP37;A0A0G2JLQ8;A0A0G2JNC8;Q9NX02-4;Q9NX02-5;Q9NX02-2;Q9NX02-3;K7EMK2 Q9NX02 NLRP2 NACHT, LRR and PYD domains-containing protein 2 1 ENLPENVT(0.005)AS(0.76)ES(0.235)DAEVER 172.69 4.6458e-25 0.0 7906.3 7801.5 9993.9 7942.9 8843.8 8526.3 6993.3 6417.8 10054.0 5373.2 True False 7793.554712162156 7783.436106072733 9172.240119569615 8527.047362737658 8323.625071579785 8161.6500247760705 7355.3788555203055 6715.994417330779 8921.612646686424 6301.950460661047 1.2366893013222204 1.2350836704699015 1.4554605239799816 1.3530806717644694 1.320801412759229 1.2950990452438353 1.1671591043812741 1.0657009221596292 1.4156906980431239 1.0 12.621582698103616 -7.19976594685679 3.9251651048280314 1.1668281564430976 1.3231719491482914 0.2992746860478007 0.11564858179397029 0.3070319649718909 9.534740771772574 0.04635006797018748 0.034340739004909936 6.312974762496311e-08 7.19976594685679 0.15634379270519383 ENLPENVTASES(ph)DAEVER ddPTM_PC-9_AZD4547_30min_R2 2 ENLPENVTASESDAEVER 18 0 Q9NX02;A0A0G2JPQ2;J3KN39;A0A0G2JLX3;A0A0G2JMG8;A0A0G2JPB6;A0A0G2JP37;A0A0G2JLQ8;A0A0G2JNC8;Q9NX02-4;Q9NX02-5;Q9NX02-2;Q9NX02-3;K7EMK2 Q9NX02 NLRP2 NACHT, LRR and PYD domains-containing protein 2 1 ENLPENVTASES(1)DAEVER;ENLPENVTASES(1)DAEVER 279.97 5.1640999999999986e-92 40586000.0 76129.0 79572.0 104268.0 129739.0 107610.0 104988.0 100301.0 123777.0 88622.0 101731.0 True False 100336.43841843035 105292.09288473 102885.33819249905 99829.67799756862 92670.20898380886 98423.08376318436 109227.59469121628 104650.10876249977 93306.37799460116 98169.42865450672 1.022074181276435 1.0725548098613316 1.0480384739182838 1.0169120811419299 0.9439823604347176 1.0025838503101647 1.1126436833571396 1.066015257466771 0.9504626773675096 1.0 16.582986198434597 -5.752850195943918 7.169108611633147 1.0167522079580926 1.0502234852545866 0.09305777172092933 0.04804841958146875 0.3946086940050599 107.04813154306089 0.014422597829207585 0.023689767793814025 1.7666470968182649e-06 5.752850195943918 0.03347127729649402 ENLPENVTASES(ph)DAEVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ENLPENVTASESDAEVER 18 0 Q9NX02;A0A0G2JPQ2;J3KN39;A0A0G2JLX3;A0A0G2JMG8;A0A0G2JPB6;A0A0G2JP37;A0A0G2JLQ8;A0A0G2JNC8;Q9NX02-4;Q9NX02-5;Q9NX02-2;Q9NX02-3;K7EMK2 Q9NX02 NLRP2 NACHT, LRR and PYD domains-containing protein 2 1 ENLPENVTAS(0.001)ES(0.999)DAEVER;ENLPENVT(0.009)AS(0.06)ES(0.931)DAEVER 237.66 1.9370999999999997e-43 21262000.0 49438.2 55963.5 59635.3 58147.3 72399.0 58893.4 56264.4 55749.6 59321.1 50160.7 True False 57807.11081104105 61519.18643011325 61057.23172013471 54889.495297090114 58212.93567057009 55804.92642809462 50934.62871301957 54286.23207158385 60188.55886300461 59254.43783811725 0.9755743691125669 1.0382207421861511 1.0304246221513853 0.9263356011755249 0.9824232208498452 0.9417847584775563 0.8595917971945436 0.9161547059123823 1.0157645749241495 1.0 15.854635587691716 -5.759997657013675 24.999754686929954 0.9427549323873029 1.0170880056048521 0.30197068207298305 0.04519185573771336 43.32627845352756 751253.2906005303 0.012853090527080462 0.020802035239113278 1.737810204080471e-06 5.759997657013675 0.07433307321754923 ENLPENVTASES(ph)DAEVER ddPTM_PC-9_Lapatinib_30min_R1 3 ENLPENVTASESDAEVER 18 0 Q9NX02;A0A0G2JPQ2;J3KN39;A0A0G2JLX3;A0A0G2JMG8;A0A0G2JPB6;A0A0G2JP37;A0A0G2JLQ8;A0A0G2JNC8;Q9NX02-4;Q9NX02-5;Q9NX02-2;Q9NX02-3;K7EMK2 Q9NX02 NLRP2 NACHT, LRR and PYD domains-containing protein 2 1 ENLPENVTASES(1)DAEVER;ENLPENVTASES(1)DAEVER;ENLPENVT(0.001)AS(0.003)ES(0.996)DAEVER 219.99 7.122299999999999e-28 36590500.0 92011.0 77661.0 97364.0 76512.0 88252.0 82546.0 76436.0 77450.0 95382.0 68891.0 True False 90698.9062672491 77481.18072597773 89359.10775590873 82138.94771654971 83061.19087010765 79015.70000412439 80393.48207577966 81048.60974512598 84639.07474301223 80798.71755851277 1.1225290327357833 0.9589407241503239 1.1059471048064184 1.0165872701762422 1.02800135175359 0.9779326008101904 0.9949846297691588 1.0030927741697415 1.0475299274610188 1.0 16.302044774176807 -5.974669029364842 24.997486339116332 1.0079646433089102 1.0536438292368873 0.22429276933419107 0.044242443857594224 369.05784461713745 364196.68471315026 0.011766665130288269 0.017452308294638317 1.0600612774578298e-06 5.974669029364842 0.04567918592797704 ENLS(ph)PGFSHLLSK ddPTM_PC-9_AZD4547_30min_R2 1 ENLSPGFSHLLSK 13 0 F5H1U6;H0YG46;J3KNE4;A0A0A0MTP3;Q99550-2;Q99550 F5H1U6 MPHOSPH9 M-phase phosphoprotein 9 1 ENLS(0.999)PGFSHLLSK 74.618 0.010926 3091100.0 24629.0 20929.0 32254.0 36384.0 34691.0 32968.0 30161.0 37861.0 24902.0 32770.0 True False 32460.50968497573 27693.889961098346 31826.290885610786 27996.23092719643 29874.753460248165 30906.505748320415 32845.27057040091 32010.452409227917 26218.26888155941 31622.732274411712 1.0264928850326422 0.8757589230677426 1.006437097510508 0.8853197972981686 0.9447239789719889 0.9773508968208022 1.0386601096129333 1.0122608043938677 0.8290956219103985 1.0 14.948674404691888 -6.755734935890194 10.052485749790774 0.9764511506120017 0.9435211589285885 0.025177313181431682 0.0680032844613146 0.49283421338908445 637.8379692135375 0.022483265107320977 0.021453660632140322 1.7549512791396182e-07 6.755734935890194 -0.03292999168341326 ENLS(ph)PGFSHLLSK ddPTM_PC-9_Lapatinib_30min_R1 1 ENLSPGFSHLLSK 13 0 F5H1U6;H0YG46;J3KNE4;A0A0A0MTP3;Q99550-2;Q99550 F5H1U6 MPHOSPH9 M-phase phosphoprotein 9 1 ENLS(0.999)PGFS(0.001)HLLSK 91.51799999999999 0.0082196 0.0 25759.0 18612.0 26377.0 18707.0 23180.0 26323.0 24741.0 24265.0 29098.0 20302.0 True False 25391.67193637793 18568.905057517863 24208.38487816447 20082.77518472263 21816.597973633423 25197.226651910023 26021.967921357278 25392.440483737602 25820.67682447599 23811.17364928543 1.0663763286250247 0.7798399747538322 1.0166817156822912 0.8434181145592254 0.9162336260685805 1.0582101925356455 1.0928469257599234 1.0664086053775694 1.0843932854712883 1.0 14.539351112138961 -6.771328778032885 6.617915014743746 1.067178231669733 0.9167616260441165 0.4241128071095852 0.07873977014179956 0.1269171268321677 24.17259457730139 0.025229025093344824 0.02328861816843862 1.6930556053771723e-07 6.771328778032885 -0.15041660562561643 ENNSGTCLDS(ph)PLPLR ddPTM_PC-9_AZD4547_30min_R2 1 ENNSGTCLDSPLPLR 15 0 Q17RS7 Q17RS7 GEN1 Flap endonuclease GEN homolog 1 1 ENNS(0.005)GT(0.01)CLDS(0.985)PLPLR 99.39200000000001 0.0020709 2183900.0 2617.8 2654.8 5726.0 6681.5 4459.0 4615.9 5594.8 5482.1 4956.4 4310.2 True False 3450.205946377419 3512.9121825564457 5650.069498698063 5141.183403145966 3839.9448179425954 4327.2670433047815 6092.726361436261 4634.967411125656 5218.385185308851 4159.301209922774 0.8295157701361761 0.8445919170690862 1.3584179681959048 1.2360690278647604 0.9232187389510776 1.0403831857575725 1.4648437451226055 1.1143620471794862 1.2546302664638564 1.0 12.022125451090602 -5.237694195100555 22.938841240010273 1.1769518231313565 0.8370534178970783 0.42693994206888963 0.15611376170761054 266.13279654514724 257091.75897004677 0.040685119610770884 0.10744357201742775 5.7850325234693156e-06 5.237694195100555 -0.33989840523427817 ENNSGTCLDS(ph)PLPLR ddPTM_PC-9_Lapatinib_30min_R1 2 ENNSGTCLDSPLPLR 15 0 Q17RS7 Q17RS7 GEN1 Flap endonuclease GEN homolog 1 1 ENNSGTCLDS(1)PLPLR;ENNS(0.008)GT(0.267)CLDS(0.726)PLPLR 124.04 3.0354e-05 4802000.0 12233.599999999999 12809.8 13910.3 13300.900000000001 8932.099999999999 9754.0 11249.1 11519.5 12854.8 11641.2 True False 12059.146620632517 12780.139695131767 12766.648829310796 14279.092556501695 8406.731439184261 9336.84415768455 11831.523355730973 12054.738024002289 11406.957056954903 13653.365909076034 0.8832361705487022 0.9360431545042097 0.9350550563377346 1.0458294790890876 0.6157259312588929 0.6838492588467077 0.8665645844784694 0.8829132760580992 0.8354684942100733 1.0 13.736969036315111 -6.235569487089853 24.999604262439934 0.8043445383879205 0.9479706861225167 0.27838805690764423 0.10652053910842545 1032.2463854246523 997520.7749282126 0.03269329453691962 0.04219236449777195 5.813404104377076e-07 6.235569487089853 0.14362614773459614 ENPEDVLS(ph)PTSVATYLSSK ddPTM_PC-9_AZD4547_30min_R2 1 ENPEDVLSPTSVATYLSSK 19 0 Q5JTU8;B1AMJ5;A0A0A0MRG9;Q96SN8-4;Q96SN8-3;Q96SN8-2;Q96SN8 Q5JTU8 CDK5RAP2 CDK5 regulatory subunit-associated protein 2 1 ENPEDVLS(0.747)PT(0.237)S(0.016)VATYLSSK 186.6 6.262e-11 2646500.0 17673.0 19077.0 21731.0 18574.0 18507.0 22135.0 20370.0 22117.0 19651.0 19684.0 True False 23292.646378763908 25243.267178932252 21442.832741216836 14292.051265439371 15937.622504073484 20750.8949508333 22182.890538081174 18699.325848099477 20689.71174168839 18994.86915134331 1.2262599017228113 1.328951885785802 1.1288749909446154 0.7524164105351914 0.8390488177143552 1.092447375420104 1.1678359224976502 0.9844408876476555 1.0892263366934127 1.0 14.213322153391905 -5.523164667008815 24.999954070417665 0.9900504382699546 1.2654328213353645 0.49480521355300444 0.11700416254665207 8.418545592644413 736072.225663374 0.035136212359894434 0.06162969263141073 2.9980255726831566e-06 5.523164667008815 0.27538238306540985 ENPEDVLSPT(ph)SVATYLSSK ddPTM_PC-9_AZD4547_30min_R2 1 ENPEDVLSPTSVATYLSSK 19 0 Q5JTU8;B1AMJ5;A0A0A0MRG9;Q96SN8-4;Q96SN8-3;Q96SN8-2;Q96SN8 Q5JTU8 CDK5RAP2 CDK5 regulatory subunit-associated protein 2 1 ENPEDVLS(0.187)PT(0.626)S(0.187)VATYLSSK 243.09 3.6338e-53 4517900.0 21513.0 18029.0 23575.0 24492.0 23344.0 23798.0 21434.0 28242.0 25899.0 24380.0 True False 28353.686501802058 23856.521673689236 23262.38009636864 18845.747797627926 20103.088546771025 22309.907297941303 23341.584476840053 23877.847836597433 27267.968266143573 23526.46362069446 1.2051826810409982 1.0140292250597513 0.9887750437726848 0.8010446491860655 0.8544883273101807 0.9482898772052148 0.9921416517656405 1.0149357005612134 1.1590338737589951 1.0 14.52199685776934 -9.618257752399412 10.390577947307097 1.0000404359414397 0.9866902224655334 0.0 0.11508118411130364 0.0 0.0 0.11932322736121526 0.028940133529404815 2.408475581794649e-10 9.618257752399412 -0.013350213475906259 ENPEDVLSPT(ph)SVATYLSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENPEDVLSPTSVATYLSSK 19 0 Q5JTU8;B1AMJ5;A0A0A0MRG9;Q96SN8-4;Q96SN8-3;Q96SN8-2;Q96SN8 Q5JTU8 CDK5RAP2 CDK5 regulatory subunit-associated protein 2 1 ENPEDVLS(0.335)PT(0.553)S(0.11)VAT(0.001)YLSSK 155.76 2.3613e-20 0.0 2300.5 2069.1 1153.9 2924.7 2843.2 872.49 4667.0 892.14 2170.2 2101.2 True False 2689.929213053871 2274.5065737944806 1181.4133521901192 2760.8385410053356 2286.0953700819764 826.7350884691369 4224.907973846025 868.7222703004647 2201.935069384969 2482.1309269099524 1.0837176975199332 0.9163523765549519 0.47596737923123217 1.1122856216301011 0.9210212665646835 0.33307473006605404 1.702129379253046 0.3499905105255475 0.8871147954013031 1.0 11.27736350110615 -4.8493636029942175 4.607905002206615 0.8401281582872402 1.0839057030176669 0.03214403473794514 0.3850725469568049 0.7645446120493469 26.209192803483404 0.09100220611701329 0.4632290737620799 1.4146089354737402e-05 4.8493636029942175 0.24377754473042668 ENPEDVLSPT(ph)SVATYLSSK ddPTM_PC-9_Lapatinib_30min_R1 1 ENPEDVLSPTSVATYLSSK 19 0 Q5JTU8;B1AMJ5;A0A0A0MRG9;Q96SN8-4;Q96SN8-3;Q96SN8-2;Q96SN8 Q5JTU8 CDK5RAP2 CDK5 regulatory subunit-associated protein 2 1 ENPEDVLS(0.313)PT(0.536)S(0.151)VATYLSSK 176.48 2.6371000000000002e-08 6387200.0 25338.0 30284.0 30824.0 31792.0 39660.0 41931.0 47368.0 37946.0 46410.0 38077.0 True False 24976.675473579882 30213.87925864341 28289.76970408088 34130.08973500301 37327.27677456004 40137.70887593509 49820.48326659599 39709.1096886836 41182.81708103415 44658.558715586725 0.5592808230253639 0.6765529414207935 0.633468041014212 0.7642452133837211 0.8358370231400254 0.8987685682280254 1.1155864564256 0.8891713219312726 0.9221707611146108 1.0 15.446649070758452 -6.22415606596566 1.1045496863379394 0.9749471039437266 0.6082452161639805 0.8424608314363198 0.0648560179222743 0.19432047866449711 0.49174080451158153 0.028295828736549754 0.04424623574569325 5.968207774140846e-07 6.22415606596566 -0.3667018877797461 ENPPGPPIAASAPGPS(ph)QSLGLNVHNMTPATSPIGASGVAHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENPPGPPIAASAPGPSQSLGLNVHNMTPATSPIGASGVAHR 41 0 O95155-2;O95155;O95155-4 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 ENPPGPPIAAS(0.033)APGPS(0.321)QS(0.321)LGLNVHNMT(0.06)PAT(0.125)S(0.125)PIGAS(0.016)GVAHR 40.384 0.013468 8788600.0 3844.5 5022.2 11973.0 14102.0 18877.0 19867.0 14644.0 13930.0 17312.0 12074.0 True False 4495.297917663818 5520.770825436488 12258.481727855353 13311.910659300858 15178.187359678337 18825.139546145336 13256.814306621209 13564.352260055013 17565.155248913732 14262.920622268584 0.3151737317142006 0.3870715522890138 0.8594650459399096 0.9333229155406697 1.0641710601670709 1.319865688430867 0.929460007365073 0.9510220675895159 1.23152583640474 1.0 13.799981812651522 -5.337026120665303 1.5128287448324607 1.0774354855415358 0.24824172178079265 0.8497197956656418 0.11850496144842385 0.1827737843476935 0.7121177460102057 0.03671478781686894 0.16415450162373424 4.602288922570883e-06 5.337026120665303 -0.8291937637607432 down ENPPGPPIAASAPGPSQSLGLNVHNMTPAT(ph)SPIGASGVAHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENPPGPPIAASAPGPSQSLGLNVHNMTPATSPIGASGVAHR 41 0 O95155-2;O95155;O95155-4 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 ENPPGPPIAASAPGPS(0.052)QS(0.052)LGLNVHNMT(0.141)PAT(0.335)S(0.335)PIGAS(0.083)GVAHR 49.256 0.0014002 5999700.0 3798.3 5292.3 11281.0 9612.4 13905.0 16527.0 14119.0 12452.0 17060.0 7782.9 True False 4441.277170155409 5817.684568407774 11549.98182343074 9073.84839182127 11180.415067877691 15660.29502587929 12781.546107292055 12125.148193984562 17309.470225650886 9193.878160597495 0.48306896095159674 0.6327780798032343 1.2562687498873846 0.9869445987123648 1.216071702558988 1.7033394126316717 1.3902235687732243 1.3188284619595796 1.8827169474395093 1.0 13.166457832014705 -5.014164376284488 0.6772352426101802 1.4681753187694486 6.377227308971131e-10 0.6219739501577268 0.2529536202782807 1.5457128523326265 0.6611920293433909 0.1145173075074329 1.6667935737747155 9.679114417518144e-06 5.014164376284488 -1.4681753181317259 ENPPVEDS(ph)SDEDDKR ddPTM_PC-9_Lapatinib_30min_R1 1 ENPPVEDSSDEDDKR 15 1 Q8TCJ2 Q8TCJ2 STT3B Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B 1 ENPPVEDS(0.935)S(0.065)DEDDKR 85.51 0.0026446 9161600.0 12594.0 25269.0 11886.0 6280.1 12337.0 9096.5 13738.0 11865.0 19398.0 8265.6 True False 12414.407250543256 25210.49118302273 10908.778961286827 6741.959503799462 11611.361915475216 8707.463899977194 14449.28641944975 12416.291215312056 17213.192970004307 9694.297946780303 1.2805885809055788 2.6005484173710283 1.125277871711162 0.6954561888660148 1.197751707160147 0.8982046918486903 1.4904933290449038 1.2807829183170287 1.775599745799148 1.0 13.242920707968631 -5.299510052748813 24.852350510401056 1.1769065897393738 1.940568853209979 0.3530228746781521 0.4101917714926849 463.9363113301342 302854.5466765881 0.1045801372175523 0.21770849401882053 5.017529646710925e-06 5.299510052748813 0.7636622634706052 ENPQEYPDFYDFSNAACRPS(ph)TPALSR ddPTM_PC-9_AZD4547_30min_R2 1 ENPQEYPDFYDFSNAACRPSTPALSR 26 1 H0YJ41;Q9P203-5;Q9P203 H0YJ41 BTBD7 BTB/POZ domain-containing protein 7 1 ENPQEY(0.002)PDFY(0.018)DFS(0.1)NAACRPS(0.426)T(0.426)PALS(0.027)R 52.849 0.00514 4063400.0 8350.1 10331.0 21291.0 27887.0 20788.0 21782.0 18042.0 22629.0 17413.0 23697.0 True False 11005.25810713045 13670.29371628395 21008.66742870773 21458.082999855054 17901.945026999492 20419.968096636585 19647.703048014762 19132.20801268903 18333.415630655938 22867.37524280543 0.4812645959703199 0.5978077313698221 0.9187179204275975 0.9383710536086223 0.782859634606811 0.8929738494172456 0.8592023719117635 0.8366595557882593 0.8017280267626704 1.0 14.48100315975014 -5.133232782099927 3.772332502685075 0.8712996772063423 0.5030493976662513 0.8260745187697485 0.06301410038512306 0.08751358023257709 2.15011360825131 0.01614752477516083 0.051534427464476416 7.3581259578977464e-06 5.133232782099927 -0.36825027954009093 ENPQEYPDFYDFSNAACRPS(ph)TPALSR ddPTM_PC-9_Lapatinib_30min_R1 2 ENPQEYPDFYDFSNAACRPSTPALSR 26 1 H0YJ41;Q9P203-5;Q9P203 H0YJ41 BTBD7 BTB/POZ domain-containing protein 7 1 ENPQEYPDFY(0.005)DFS(0.26)NAACRPS(0.363)T(0.363)PALS(0.008)R;ENPQEY(0.005)PDFY(0.2)DFS(0.175)NAACRPS(0.302)T(0.302)PALS(0.015)R 55.718 0.0022139 8970900.0 17649.7 14246.8 21786.0 16106.7 16659.1 13630.0 10573.8 9920.1 18619.7 12500.6 True False 17398.01204144142 14213.812409920789 19994.839176391964 17291.2404483761 15679.244491050767 13047.076673081856 11121.259625999252 10381.02406110553 16522.55331186664 14661.312053997519 1.186661328629024 0.9694775172625348 1.3637823888306244 1.1793787885212845 1.069429832289512 0.889898300031372 0.7585446367309913 0.708055597130208 1.1269491605535835 1.0 13.839726596874836 -6.6418561578746695 2.9301206765348904 0.8673308405188809 1.1708870614425182 0.4583608630284859 0.14166449646675705 0.22562530639322306 3.9003368222843235 0.050652277676484635 0.050334184196848444 2.2810974662997906e-07 6.6418561578746695 0.3035562209236373 ENPVLDVVS(ph)NPEQTAGEER ddPTM_PC-9_AZD4547_30min_R2 2 ENPVLDVVSNPEQTAGEER 19 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 ENPVLDVVS(1)NPEQTAGEER;ENPVLDVVS(1)NPEQTAGEER 181.23 3.1804e-09 3300900.0 8424.6 11202.5 10057.3 9396.6 9020.0 13551.4 8905.0 15090.2 10685.6 10467.900000000001 True False 11103.447557434187 14823.489048172589 9923.933630676918 7230.359046022812 7767.728696533356 12704.028815754336 9697.527748729155 12758.356328299076 11250.419000915235 10101.422007180792 1.0991964843703277 1.4674655744146738 0.9824293672338703 0.7157763571191236 0.7689737831972088 1.2576475675131116 0.9600160989052312 1.2630257719387974 1.1137460639618517 1.0 13.302270779289053 -5.284881042288852 24.54178435007313 1.0053672840653536 1.283331044284217 0.25664537272103616 0.18760244291605238 775.2643053112454 811646.5431864635 0.05246303451803152 0.10932501924627519 5.189421630422994e-06 5.284881042288852 0.2779637602188634 ENPVLDVVS(ph)NPEQTAGEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENPVLDVVSNPEQTAGEER 19 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 ENPVLDVVS(0.999)NPEQT(0.001)AGEER 137.99 0.00012842 1606400.0 6262.9 6858.6 6605.0 5366.6 6547.5 5081.3 5909.5 3788.0 3626.7 3722.4 True False 7323.085272086546 7539.476481091696 6762.488249601991 5065.926800751949 5264.564376622023 4814.827682882582 5349.70937892502 3688.56901371776 3679.7336264576834 4397.241653497813 1.6653815844442739 1.7145922546909318 1.5378932481963388 1.1520692288362697 1.1972424513977513 1.0949654493181191 1.2166057270629103 0.8388370038257199 0.8368277016412361 1.0 12.102383103708682 -5.625357675297112 0.5345037428006315 0.9183349907851586 1.9569210178995713 0.8607561981600016 0.11225855948543635 0.6907822985130062 0.28056583235751364 0.08139816303185328 0.40627494427166533 2.3694214989123705e-06 5.625357675297112 1.0385860271144127 ENPVLDVVS(ph)NPEQTAGEER ddPTM_PC-9_Lapatinib_30min_R1 2 ENPVLDVVSNPEQTAGEER 19 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 ENPVLDVVS(1)NPEQTAGEER;ENPVLDVVS(0.991)NPEQT(0.009)AGEER 151.64 3.7606e-05 3392400.0 6788.3 11974.2 10492.2 11097.3 11224.9 11315.5 10807.3 10952.7 10815.7 8832.599999999999 True False 6691.497597178245 11946.474475592651 9629.571817063244 11913.432461507575 10564.67345100249 10831.562442718832 11366.84911347497 11461.602426797159 9597.521971629832 10359.303141300295 0.6459409002619776 1.1532121719620934 0.9295578752466688 1.1500225738168914 1.0198247224645283 1.045587941097673 1.0972600143495952 1.1064067023101425 0.9264640527186229 1.0 13.33863933736117 -4.752484562069495 24.999997807258318 1.0510521259979377 0.6459401244296012 0.7097713624193106 0.07702307763706503 174.41045978533043 486882.29203672183 0.017623272176152987 0.2085342491926647 1.7681350687773443e-05 4.752484562069495 -0.4051120015683365 ENPVLDVVSNPEQT(ph)AGEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENPVLDVVSNPEQTAGEER 19 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 ENPVLDVVS(0.029)NPEQT(0.971)AGEER 108.13 0.00046289 1697900.0 9003.2 12231.0 10667.0 7362.9 11487.0 7358.2 8616.2 9727.1 6479.5 7169.0 True False 10527.263938694468 13445.212848137004 10921.341734822776 6950.380583843878 9236.204810119463 6972.323038629215 7800.011160114016 9471.773931714368 6574.250429490324 8468.682950227221 1.243081598468864 1.5876391792157314 1.2896151383881655 0.820715644297133 1.0906306050661216 0.8233066557819528 0.9210418203110008 1.1184471053388807 0.7763013998905145 1.0 13.047921903697716 -5.624084891629065 4.9378285081086375 0.9431627225934824 1.420769416832626 0.7011921660992197 0.13223252433684263 0.1003836164144776 3.9815950346771953 0.033896524918918834 0.06023106012177505 2.376375730584533e-06 5.624084891629065 0.4776066942391435 ENPYYDSR ddPTM_PC-9_AZD4547_30min_R2 1 ENPYYDSR 8 0 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 124.08 0.015285 12804000.0 31744.0 33163.0 57353.0 57583.0 50032.0 42762.0 31068.0 47532.0 38659.0 41165.0 False True 41837.9316837821 43882.291212189 56592.461746215544 44308.12899848149 43085.920415183704 40088.085380055716 33832.99181330908 40187.02157669954 40702.43581608726 39723.82587965086 1.053220095429283 1.1046844114445777 1.4246478150838413 1.1154043704833327 1.0846367252167202 1.0091697990397106 0.8517052691704742 1.0116603999436509 1.0246353394912473 1.0 15.277716957898871 -6.506855352177782 2.0851220871067833 0.9709675321905937 1.1884396264739248 0.44825486487578325 0.10271248906696771 0.3021997637076461 2.635040952705026 0.039348844776067884 0.042964329233216615 3.1127529101575697e-07 6.506855352177782 0.21747209428333103 ENPYYDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ENPYYDSR 8 0 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 ; 123.21 0.015182 14016100.0 71956.0 64416.0 78355.0 83651.0 78473.0 82086.0 82305.0 85335.0 67563.0 54474.0 False True 84136.72960421859 70810.79476948675 80223.28036299213 78964.30567020123 63096.77897314398 77781.26565585565 74508.47456340179 83095.04666990643 68550.9810583616 64349.70498405324 1.3074920798015912 1.1004058959871634 1.2466767389667532 1.2271121629814727 0.980529421056091 1.2087276184891746 1.157868160885369 1.2913042366005958 1.0652881947997974 1.0 15.973645913869257 -14.52287874524853 0.21528413396824045 0.13462199439150288 1.198677132234172 0.256659925293233 0.09589144656424499 224.40381032376308 2.236244751877953 84.03093452878397 0.1897703093082022 3.0000000002197193e-15 14.52287874524853 1.0640551378426693 ENPYYDSR ddPTM_PC-9_Lapatinib_30min_R1 1 ENPYYDSR 8 0 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 117.81 0.016266 16562000.0 45492.0 52311.0 66817.0 56300.0 50642.0 57739.0 51550.0 53731.0 74439.0 47006.0 False True 44843.27573778892 52189.87709347824 61323.564181078786 60440.48981129438 47663.33712600275 55269.63756618292 54219.0067639128 56227.53841465922 66054.8959425791 55130.9244684421 0.8133960416981216 0.9466534000051574 1.1123260633182646 1.0963082951001768 0.864548120416266 1.0025160669638367 0.9834590529122853 1.0198910857525134 1.1981459875643854 1.0 15.750574173157949 -8.030084970129323 10.95889434618287 1.1024849228102434 0.9815274692984813 0.2052177933825643 0.09672126862679574 1.4022961557009708 503.23663730931145 0.06498451195098638 0.025321669255218837 9.330717265645219e-09 8.030084970129323 -0.12095745351176201 ENQEPLRS(ph)PEVGDEEALRPLTK ddPTM_PC-9_AZD4547_30min_R2 1 ENQEPLRSPEVGDEEALRPLTK 22 2 P48681 P48681 NES Nestin 1 ENQEPLRS(1)PEVGDEEALRPLTK 49.592 0.013166999999999998 23044000.0 27393.0 27000.0 30112.0 27706.0 26737.0 34858.0 27602.0 33798.0 36462.0 32876.0 True False 36103.40419020425 35727.22198622269 29712.69520516871 21318.809753432946 23025.02906421421 32678.32374954356 30058.524527840786 28575.295700776143 38389.30688135166 31725.021246675617 1.1380104022463795 1.12615281510541 0.9365697496036265 0.6719872490445342 0.7257687515852158 1.0300489161364341 0.94747058777748 0.9007179373842177 1.2100640243187977 1.0 14.953333509808527 -9.611949882551901 15.791046607458634 0.9999999999998496 0.9529143310518817 0.0 0.16428153267002185 0.0 0.0 0.1717574918352077 0.04165731063692497 2.443712540089897e-10 9.611949882551901 -0.04708566894796784 ENQEPLRS(ph)PEVGDEEALRPLTK ddPTM_PC-9_Lapatinib_30min_R1 2 ENQEPLRSPEVGDEEALRPLTK 22 2 P48681 P48681 NES Nestin 1 ENQEPLRS(1)PEVGDEEALRPLTK;ENQEPLRS(1)PEVGDEEALRPLTK 59.983000000000004 0.0025391 36850000.0 69483.0 70534.0 61555.0 56151.0 74050.0 85492.0 82540.0 86940.0 74322.0 64242.0 True False 68492.1596783782 70370.68285659607 56494.18550917135 60280.531854244924 69694.52458790135 81835.70645158582 86813.51732867821 90979.5497900741 65951.07371464383 75346.14410291584 0.9090333751495533 0.9339652837506356 0.7497953104541825 0.8000479994292383 0.92499125758453 1.0861299861583604 1.152195886893681 1.2074878001162803 0.875307880713322 1.0 16.20124606222933 -6.6376643959648645 3.5527343964220437 1.0831828551463183 0.848331194290754 0.5234285406257164 0.09689182132652278 0.18121473229809945 4.428002058254353 0.034196151983933304 0.03402624287796467 2.3032209596678717e-07 6.6376643959648645 -0.2348516608555643 ENQGS(ph)HESPTLNPETVAINLSDVDLSK ddPTM_PC-9_AZD4547_30min_R2 1 ENQGSHESPTLNPETVAINLSDVDLSK 27 0 P25445-6;P25445 P25445-6 FAS Tumor necrosis factor receptor superfamily member 6 1 ENQGS(0.375)HES(0.274)PT(0.35)LNPET(0.002)VAINLSDVDLSK 76.00399999999999 2.7805999999999998e-05 2218500.0 9446.7 12503.0 13822.0 16276.0 13822.0 11435.0 11738.0 17067.0 12298.0 9625.0 True False 12450.55409643348 16544.350240508975 13638.711248865638 12523.819661693298 11903.053885086922 10719.967642321155 12782.659260480947 14429.68731064401 12948.047173135395 9288.031679621996 1.3404943615502602 1.781254716950136 1.4684178219147404 1.3483825307326032 1.281547511428315 1.1541700127747019 1.3762506095372378 1.5535786061435215 1.3940571716118817 1.0 13.181157177618754 -5.64919437258044 3.5702398217003295 1.319506821548919 1.5731573831709955 0.2752420920360571 0.17149106094191274 0.3016865993912438 7.365157317060799 0.0478292834016078 0.08796992711663151 2.24287787802318e-06 5.64919437258044 0.25365056162207655 ENQGS(ph)HESPTLNPETVAINLSDVDLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENQGSHESPTLNPETVAINLSDVDLSK 27 0 P25445-6;P25445 P25445-6 FAS Tumor necrosis factor receptor superfamily member 6 1 ENQGS(0.55)HES(0.355)PT(0.093)LNPET(0.002)VAINLSDVDLSK 53.678999999999995 0.0035669000000000005 1661200.0 6146.8 4429.9 4458.8 4167.9 8243.8 3941.7 4561.1 2947.6 3304.5 4129.2 True False 7187.331835166071 4869.671195810821 4565.114702093168 3934.3860755141172 6628.48656861346 3734.990313033726 4129.039588495631 2870.2286232403567 3352.822061000196 4877.791273270784 1.4734808097572887 0.9983352962426951 0.9358979190251508 0.806591724634402 1.3589114821161166 0.76571343540275 0.84649780139668 0.5884279302742154 0.6873648077917803 1.0 12.252012309409572 -6.869411988629092 11.510841893996627 0.7549345084707194 1.0810275441092454 0.3879638391488819 0.20861568481595158 0.44985423135330943 45.0890253819256 0.07383262324906886 0.06512215742809731 1.3507905427812321e-07 6.869411988629092 0.326093035638526 ENQGS(ph)HESPTLNPETVAINLSDVDLSK ddPTM_PC-9_Lapatinib_30min_R1 1 ENQGSHESPTLNPETVAINLSDVDLSK 27 0 P25445-6;P25445 P25445-6 FAS Tumor necrosis factor receptor superfamily member 6 1 ENQGS(0.528)HES(0.415)PT(0.057)LNPETVAINLSDVDLSK 89.565 2.4934000000000003e-07 2177400.0 20721.0 20799.0 10657.0 9908.4 12175.0 9130.2 9390.2 7318.8 13992.0 6056.3 True False 20425.51474023399 20750.841193386757 9780.82259720964 10637.096789453444 11458.890436970967 8739.722629535723 9876.37860939853 7658.858166592988 12416.073617708029 7103.123385487511 2.875568060941422 2.921368539899375 1.3769748977179495 1.4975238655133378 1.6132185540212893 1.2304055772692857 1.390427572971222 1.0782380863946284 1.747973805871862 1.0 12.794237830673604 -5.2619182563889115 24.829439072907906 1.379074990320297 2.898468449238048 0.8902806823727623 0.21504072251870524 9.976706872464774 517324.86472511303 0.052982992874799725 0.12227403503732112 5.47118932815138e-06 5.2619182563889115 1.519393458917751 ENQGSHES(ph)PTLNPETVAINLSDVDLSK ddPTM_PC-9_AZD4547_30min_R2 1 ENQGSHESPTLNPETVAINLSDVDLSK 27 0 P25445-6;P25445 P25445-6 FAS Tumor necrosis factor receptor superfamily member 6 1 ENQGS(0.04)HES(0.746)PT(0.214)LNPETVAINLSDVDLSK 100.95 8.609e-10 1868300.0 5667.4 9167.9 8920.5 10220.0 10209.0 7139.9 10524.0 11012.0 9349.2 8311.7 True False 7469.515310756891 12131.244386944112 8802.208341448839 7863.936897425991 8791.6565701673 6693.440924303352 11460.615612310574 9310.348430586035 9843.37962522992 8020.709912884583 0.9312785765706044 1.5124901060760605 1.0974350695951296 0.9804539726331769 1.0961195038414564 0.8345197615925385 1.4288779592813945 1.1607885750399423 1.2272454348981472 1.0 12.969514219904788 -10.817362769503646 14.81727636506142 1.000014392817262 1.1446562301954426 0.04292533718699487 0.1991049136628212 0.0 0.0 0.19046907272300423 0.0461955356029646 1.522780232418491e-11 10.817362769503646 0.1446418373781806 ENQGSHES(ph)PTLNPETVAINLSDVDLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENQGSHESPTLNPETVAINLSDVDLSK 27 0 P25445-6;P25445 P25445-6 FAS Tumor necrosis factor receptor superfamily member 6 1 ENQGS(0.002)HES(0.816)PT(0.182)LNPETVAINLSDVDLSK 94.00299999999999 1.929e-09 1560000.0 12249.0 10876.0 13490.0 11100.0 22388.0 10978.0 10794.0 10096.0 10356.0 10188.0 True False 14322.513771222282 11955.697403020042 13811.652761109895 10478.102986685544 18001.232113602724 10402.294354335507 9771.514178207412 9830.99069759623 10507.436908372838 12035.003751836373 1.1900714006039979 0.9934103594438655 1.1476234694984977 0.8706356227838095 1.49573963455192 0.8643366108422078 0.8119244812629506 0.8168664422805982 0.8730730064599731 1.0 13.554948971112992 -6.938195849530135 24.999999956993676 0.857040524240466 1.123209932906224 0.41240953696771776 0.15774360193220077 65.51388345065205 26500.08871290097 0.05294987017306522 0.04669739132834751 1.1529332135678293e-07 6.938195849530135 0.266169408665758 ENQPENS(ph)QTPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENQPENSQTPTK 12 0 Q12834 Q12834 CDC20 Cell division cycle protein 20 homolog 1 ENQPENS(0.604)QT(0.39)PT(0.005)K 97.551 0.0039355 4046000.0 14958.0 22647.0 20461.0 24151.0 24867.0 22242.0 20291.0 21774.0 18506.0 16359.0 True False 17490.093966033397 24895.244491191137 20948.867838774615 22797.89776859844 19994.48985925313 21075.590365196767 18368.889585881643 21202.455571460014 18776.615240087638 19324.757202227243 0.9050615116663719 1.288256521449174 1.0840430034670856 1.1797249264260306 1.0346567178059396 1.0906005257736295 0.9505366299642082 1.0971654313471197 0.9716352471390207 1.0 14.238162667679227 -6.676088005298371 1.7236289841689174 1.0162349125511327 1.1224725083253753 0.15671127669378127 0.09948679455670308 0.6073424095709051 3.7234651362721696 0.03820192412787557 0.037186717505426604 2.1082009014728083e-07 6.676088005298371 0.10623759577424252 ENQPENSQT(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 2 ENQPENSQTPTK 12 0 Q12834 Q12834 CDC20 Cell division cycle protein 20 homolog 1 ENQPENS(0.004)QT(0.978)PT(0.019)K;ENQPENS(0.022)QT(0.978)PT(0.001)K 153.14 0.00051248 9208900.0 47883.8 37677.2 53338.0 61612.0 61443.0 57753.0 53849.0 59424.0 55944.0 56042.0 True False 63109.852355087154 49855.61808219665 52630.703269569894 47408.30529591102 52912.70003338122 54141.695780233815 58641.45668066434 50241.38622767391 58901.08562806042 54079.986637857226 1.1669724102873358 0.9218866568154175 0.9732011145270365 0.8766330807989535 0.9784155530160785 1.0011410717016227 1.0843467302119114 0.9290199452916246 1.089147562525992 1.0 15.722807174706908 -6.897220029567403 4.332005088084234 1.022393771099146 0.9737311670650642 0.04789934846923083 0.08189553577214173 0.6505933907301066 21.76708603950461 0.02923341950483236 0.025618183452056596 1.2670097894340874e-07 6.897220029567403 -0.048662604034081736 ENQPENSQT(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENQPENSQTPTK 12 0 Q12834 Q12834 CDC20 Cell division cycle protein 20 homolog 1 ENQPENS(0.002)QT(0.996)PT(0.001)K 157.37 0.0010241 4307600.0 21339.0 26216.0 23685.0 24175.0 28702.0 25443.0 23984.0 20750.0 20267.0 18250.0 True False 24951.27123553862 28818.551224491872 24249.740225862697 22820.553126407496 23078.04913903097 24108.724290158327 21712.061890877012 20205.33448644233 20563.36653360295 21558.580533079494 1.15737078316698 1.3367555057844684 1.124830096705759 1.0585369055904044 1.0704809207461503 1.118289038240059 1.0071192701004603 0.9372293530846921 0.9538367566478004 1.0 14.395974570380902 -5.899068027794885 0.5045930693427261 0.9602605023994789 1.299181177906557 0.6760341673821417 0.06333582518378636 0.9747029651466602 0.40866288889673374 0.05045594412628094 0.17484017809143615 1.2616298976744697e-06 5.899068027794885 0.33892067550707805 ENQPENSQT(ph)PTKK ddPTM_PC-9_AZD4547_30min_R2 5 ENQPENSQTPTKK 13 1 Q12834 Q12834 CDC20 Cell division cycle protein 20 homolog 1 ENQPENS(0.002)QT(0.785)PT(0.213)KK;ENQPENS(0.003)QT(0.994)PT(0.004)KK;ENQPENS(0.001)QT(0.937)PT(0.062)KK;ENQPENSQT(0.632)PT(0.368)KK;ENQPENS(0.002)QT(0.74)PT(0.258)KK 266.45 6.0557000000000004e-55 373129500.0 543281.0 440609.0 546772.0 596209.0 661608.0 661757.0 567036.0 561028.0 521667.0 611134.0 True False 716033.0570531999 583027.2426713923 539521.4460255215 458762.2263872266 569755.1493853715 620377.2301774819 617501.1055057138 474334.0137409026 549241.2526157119 589738.3846747128 1.21415372589008 0.9886201370341152 0.914848787268799 0.7779080322883682 0.9661150845720113 1.0519532835219279 1.0470763334259043 0.8043126004126986 0.9313303439094638 1.0 19.169715573256 -4.771191785413741 3.120624293492894 0.9336995552344177 1.2606876323928795 0.4822663423240642 0.08586861590442844 0.3429272878188351 4.894988510775713 0.0235304845881349 0.2834267413744985 1.6935897422724942e-05 4.771191785413741 0.3269880771584618 ENQPENSQT(ph)PTKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ENQPENSQTPTKK 13 1 Q12834 Q12834 CDC20 Cell division cycle protein 20 homolog 1 ENQPENS(0.006)QT(0.953)PT(0.04)KK;ENQPENS(0.001)QT(0.955)PT(0.045)KK;ENQPENS(0.039)QT(0.789)PT(0.173)KK;ENQPENS(0.037)QT(0.82)PT(0.143)KK;ENQPENS(0.058)QT(0.858)PT(0.084)KK 111.81 0.0017899 319165700.0 572579.6 557212.6 504769.0 683331.0 685948.0 698599.9 697637.0 643469.1 562085.6 509279.8 True False 669506.0173174088 612528.9844382163 516804.60730709386 645046.1794589943 551541.4135189186 661964.0914291634 631551.7729055093 626578.7179368671 570305.038538517 601608.1962833214 1.1128605319102263 1.018152658528196 0.8590385079522918 1.0722031106690844 0.9167784231104054 1.1003242567483538 1.049772554308895 1.0415062856653405 0.947967534454829 1.0 19.198464696799356 -6.769272997314815 24.999178692286808 1.0318743941980875 0.9936941075663549 0.04083769816886662 0.07626632694088757 616.353446129182 1966934.923994134 0.026597456365094828 0.023876679388216908 1.7010888685495494e-07 6.769272997314815 -0.03818028663173256 ENQPENSQT(ph)PTKK ddPTM_PC-9_Lapatinib_30min_R1 5 ENQPENSQTPTKK 13 1 Q12834 Q12834 CDC20 Cell division cycle protein 20 homolog 1 ENQPENS(0.001)QT(0.606)PT(0.393)KK;ENQPENS(0.056)QT(0.939)PT(0.005)KK;ENQPENS(0.002)QT(0.909)PT(0.089)KK;ENQPENS(0.006)QT(0.687)PT(0.307)KK;ENQPENS(0.021)QT(0.791)PT(0.189)KK 279.29 1.7770999999999998e-68 401342900.0 529674.0 476333.0 503485.0 526340.0 533476.0 467549.0 364109.0 444181.0 504261.0 422334.0 True False 522120.7516296841 475230.080204312 462090.40680830274 565048.7994187685 502097.99053416995 447553.0191799523 382960.7824209799 464819.27082246286 447465.816076263 495333.8691753196 1.054078439051547 0.959413659711018 0.9328867569214198 1.1407433139177765 1.0136556811067894 0.9035380922469171 0.7731366786175363 0.9383958976928825 0.903362043102863 1.0 18.918041745158177 -6.772326970895283 5.778706366269878 0.8908300251412031 1.0191076112961406 0.37549167871430067 0.07433338636931354 0.17232037814817053 19.182727658062174 0.026347702586658705 0.024343410063803302 1.689168714305154e-07 6.772326970895283 0.12827758615493745 ENQPENSQTPT(ph)KK ddPTM_PC-9_AZD4547_30min_R2 2 ENQPENSQTPTKK 13 1 Q12834 Q12834 CDC20 Cell division cycle protein 20 homolog 1 ENQPENS(0.001)QT(0.095)PT(0.904)KK;ENQPENSQT(0.063)PT(0.937)KK 90.79299999999999 0.004613399999999999 30567400.0 58760.0 43171.0 53499.0 65326.0 64387.0 58679.0 62851.0 56938.0 52935.0 65130.0 True False 77444.45771607349 57125.181495082266 52789.56830437438 50266.09997663898 55447.97645052033 55009.79285384899 68444.61724147959 48139.54040507698 55733.03603105566 62849.818524029106 1.232214500133592 0.908915615615371 0.8399319129965597 0.7997811474574259 0.8822296985522899 0.8752577834861579 1.0890185341634908 0.7659455752711838 0.8867652658336234 1.0 15.939620958485428 -4.7628281194124575 5.116512306123018 0.8859661489939067 1.252645572906185 0.5674114283349272 0.08850022003924282 0.11963757132670674 8.612273498695501 0.021922322307956828 0.1573349110340771 1.7265210614780863e-05 4.7628281194124575 0.36667942391227826 ENQPENSQTPT(ph)KK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ENQPENSQTPTKK 13 1 Q12834 Q12834 CDC20 Cell division cycle protein 20 homolog 1 ENQPENSQT(0.258)PT(0.742)KK;ENQPENS(0.004)QT(0.151)PT(0.846)KK 100.22 0.0019600999999999998 65362000.0 48117.0 46121.0 46250.0 68198.0 58093.0 57329.0 56154.0 58608.0 54888.0 42279.0 True False 56262.25774593049 50699.588076929685 47352.77540410177 64377.08716089914 46710.093674089854 54322.56631806341 50834.68660024633 57069.602100309006 55690.633162105885 49943.848019620134 1.1265102705708259 1.0151317947510305 0.9481202847145362 1.2889893292885442 0.9352521987440792 1.0876728260250015 1.0178368030488205 1.1426753116397752 1.1150649253182927 1.0 15.608019360306043 -7.756916587117223 24.973502467456758 1.0966525820405513 1.0589887364005153 0.010409013761252472 0.10064814931294398 510.95052561150305 2821363.242220034 0.04738327657546581 0.02618025768734142 1.7501828056618192e-08 7.756916587117223 -0.037663845640036 ENQPENSQTPT(ph)KK ddPTM_PC-9_Lapatinib_30min_R1 1 ENQPENSQTPTKK 13 1 Q12834 Q12834 CDC20 Cell division cycle protein 20 homolog 1 ENQPENS(0.002)QT(0.446)PT(0.552)KK 94.68799999999999 0.0031453 27842000.0 51628.0 50774.0 51378.0 55339.0 47231.0 41035.0 33688.0 36138.0 40626.0 34273.0 True False 50891.77525258435 50656.435922545235 47153.899164815295 59408.8146654923 44452.96543971876 39280.02870725707 35432.19980335004 37817.1034082551 36050.27206925429 40197.042384098124 1.2660577055966944 1.2602030626657454 1.1730688719394264 1.4779399463726295 1.105876522331013 0.9771870360988594 0.8814628565152086 0.9407931819186646 0.8968389197588257 1.0 15.29480173431766 -6.596190767297118 3.22964279685177 0.930659419542722 1.2848594329066634 0.8118617492734518 0.08008196587076609 0.10030811063116452 2.11403152972901 0.027158001829075955 0.027600433229770703 2.534015299669394e-07 6.596190767297118 0.35420001336394136 ENS(ph)FGSPLEFR ddPTM_PC-9_AZD4547_30min_R2 2 ENSFGSPLEFR 11 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 ENS(0.97)FGS(0.03)PLEFR;ENS(0.985)FGS(0.015)PLEFR 111.12 0.0018521000000000002 5059600.0 14087.2 18526.5 16682.9 15585.0 19766.7 23058.0 20959.0 24168.0 18740.8 18152.3 True False 18566.636568037287 24514.828819546492 16461.673845586796 11992.119035849713 17022.43490307825 21616.1796149227 22824.31039703699 20433.390925390777 19731.400427898516 17516.79350213011 1.059933518413602 1.3995043565801808 0.9397652511908069 0.6846069764076071 0.9717780198189958 1.234026056897576 1.3029959161339355 1.1665029289125317 1.1264276435923677 1.0 14.096451089308704 -6.759394010686467 24.999626511496903 1.1849597891120962 1.0105911509433407 0.15348299692541234 0.17910707700810477 107.80030472458792 1317596.5492370983 0.06704893844996934 0.06391941402635304 1.7402273476817422e-07 6.759394010686467 -0.17436863816875547 ENS(ph)FGSPLEFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ENSFGSPLEFR 11 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 ENS(0.938)FGS(0.062)PLEFR;ENS(0.849)FGS(0.151)PLEFR;ENS(0.764)FGS(0.236)PLEFR;ENS(0.866)FGS(0.134)PLEFR 127.3 0.00036733 40298700.0 37108.2 51709.3 46156.3 45617.6 48387.6 29869.6 42805.7 30089.699999999997 35274.1 37927.200000000004 True False 43389.885339641674 56842.65756914163 47256.84124074251 43061.79376625465 38906.39713329296 28303.185593574395 38750.834209569446 29299.877257672455 35789.916980459064 44803.10112845001 0.9684571881585459 1.268721497785931 1.054767193575678 0.961134222445829 0.8683862534816225 0.6317238066273463 0.8649141071389504 0.6539698485082543 0.7988267793751542 1.0 15.451310974059895 -6.063387666649933 1.779447418632897 0.7737659767562652 1.1209556764377973 0.5466436356358026 0.12097229065853486 0.23230991468650608 1.4688809818790718 0.03842473170245207 0.059764709675977065 8.641961622488462e-07 6.063387666649933 0.347189699681532 ENS(ph)FGSPLEFR ddPTM_PC-9_Lapatinib_30min_R1 1 ENSFGSPLEFR 11 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 ENS(0.596)FGS(0.404)PLEFR 108.23 0.0022107 2356200.0 5639.7 8855.4 7864.7 7899.2 11221.0 8034.0 7464.2 8864.3 6995.7 7345.1 True False 5559.276843805687 8834.895865374157 7218.094724619932 8480.13351895873 10561.002841334806 7690.40454816872 7850.6597533889035 9276.167738718124 6207.770598013151 8614.690748269453 0.6453251783788585 1.0255615812034737 0.8378820477183033 0.9843804922030714 1.2259294210249316 0.8927081392577665 0.9113106880784977 1.0767847633510872 0.7206028375725719 1.0 13.072583291913698 -4.755080985791012 24.979560979431803 0.9673273632840156 0.6453246367615142 0.3493354920505388 0.1303612241493208 239.73271570364494 941723.7184375114 0.03173672119639752 0.29099563201059153 1.7575958327707548e-05 4.755080985791012 -0.3220027265225014 ENS(ph)KETFSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENSKETFSGK 10 1 Q5VZL5-2;Q5VZL5-4;Q5VZL5 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 ENS(0.998)KET(0.002)FSGK 95.417 0.025281 0.0 6833.5 7390.5 3553.3 7896.5 7922.3 6984.1 10121.0 7721.0 6679.7 7780.0 True False 7990.2765822228375 8124.179997887051 3638.0241479652927 7454.084705798416 6369.982185706401 6617.841501194627 9162.265610305461 7518.331931075717 6777.377975749137 9190.452413553887 0.8694105820556717 0.8839804214540822 0.395848211193609 0.8110683098478686 0.6931086631069526 0.7200778811970968 0.9969330341989633 0.8180589586632143 0.7374368171205589 1.0 13.165920166712352 -7.219813349821929 23.36379331710488 0.8729454655296932 0.7229311694367987 0.216553332916267 0.146946563016748 394.26407499968195 221291.65832254814 0.05691706141642616 0.04408695995695539 6.028186085355893e-08 7.219813349821929 -0.15001429609289452 ENS(ph)PAAFPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENSPAAFPDR 10 0 K7EJD2;A0A0A0MR03;Q9Y5B0;A0A0J9YWJ4;A0A0J9YWB6;Q9Y5B0-4 K7EJD2 CTDP1 RNA polymerase II subunit A C-terminal domain phosphatase 1 ENS(1)PAAFPDR 78.486 0.02033 7993400.0 38804.0 67226.0 47102.0 54780.0 62659.0 38920.0 51076.0 47815.0 40845.0 38602.0 True False 45372.75078606495 73899.75299884375 48225.090315329726 51710.8541991562 50381.4187513951 36878.966685255764 46237.71152178263 46559.90691418022 41442.28085385172 45600.237026736155 0.9950112925830226 1.6206001945892328 1.0575622729121907 1.1340040660060011 1.1048499314127613 0.8087450655932562 1.0139796311732483 1.0210452828760823 0.9088172245585794 1.0 15.476753702983503 -5.937015075455089 1.3293850652783576 0.963331589404017 1.2912083989345329 0.3338720360495193 0.1670239248142329 0.4605107858713047 1.651272626606178 0.05696031547109838 0.11269557924258235 1.1560721113214248e-06 5.937015075455089 0.3278768095305159 ENS(ph)SPCQGNGEQAGR ddPTM_PC-9_AZD4547_30min_R2 2 ENSSPCQGNGEQAGR 15 0 Q5T5X7 Q5T5X7 BEND3 BEN domain-containing protein 3 1 ENS(0.661)S(0.339)PCQGNGEQAGR;ENS(0.993)S(0.007)PCQGNGEQAGR 263.04 1.9804999999999996e-61 8105400.0 18414.8 19080.1 25343.0 31938.0 22883.0 27848.0 22159.0 30927.0 20556.5 23017.0 True False 24270.323348365382 25247.369193308437 25006.93526117796 24575.187537181144 19706.090439331794 26106.660157705253 24131.10807232896 26147.942781759382 21643.07462307349 22211.181835829564 1.0927074267256753 1.1366963442071822 1.1258714392603133 1.1064331343926115 0.887214853535766 1.1753836581352808 1.086439625351331 1.177242299623125 0.974422468063377 1.0 14.43899853890567 -14.522878744692072 0.1454810223341455 0.6858415801969353 1.1171211657415596 0.10860532247144117 0.08410022751026121 350.58772234636746 3.061700700839334 31.70651356083449 0.4683863475237181 3.0000000040635947e-15 14.522878744692072 0.4312795855446243 ENS(ph)SPCQGNGEQAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ENSSPCQGNGEQAGR 15 0 Q5T5X7 Q5T5X7 BEND3 BEN domain-containing protein 3 1 ENS(0.771)S(0.229)PCQGNGEQAGR;ENS(0.65)S(0.35)PCQGNGEQAGR 92.95200000000001 0.0034295000000000003 7188700.0 14005.0 17863.2 21211.2 16001.3 14884.5 13947.7 16498.1 15741.4 14657.9 10291.9 True False 16375.769888641378 19636.540442223933 21716.95545192395 15104.799037914541 11967.989074277275 13216.258058477442 14935.28053209966 15328.204929391955 14872.244057477623 12157.739999364425 1.3469419390032573 1.6151472595441654 1.7862658235049653 1.2424018805060957 0.9843925824127617 1.0870653640535457 1.228458622480859 1.2607774907337443 1.2232737382321965 1.0 13.569587450869044 -5.906132470553559 6.238121860929014 1.1436490948619515 1.5829917428065592 0.6996142218025909 0.1324154534240299 0.12049525429082084 6.651411191160282 0.039112139107965335 0.058535312713715135 1.2412736306984517e-06 5.906132470553559 0.43934264794460764 ENS(ph)SPCQGNGEQAGR ddPTM_PC-9_Lapatinib_30min_R1 2 ENSSPCQGNGEQAGR 15 0 Q5T5X7 Q5T5X7 BEND3 BEN domain-containing protein 3 1 ENS(0.999)S(0.001)PCQGNGEQAGR;ENS(0.985)S(0.015)PCQGNGEQAGR 281.68 6.393599999999999e-76 6739000.0 11728.5 14575.099999999999 14902.099999999999 10277.2 12717.1 8667.0 11557.4 10074.1 11916.0 7649.099999999999 True False 11561.249439256511 14541.352251441473 13676.906861769523 11033.019571734183 11969.10518078057 8296.332613763783 12155.78562120749 10542.179463310162 10573.894598957175 8971.236743214915 1.2887018557391725 1.6208860235952778 1.5245285854387445 1.2298214713906226 1.33416445506613 0.9247702241319657 1.3549732293489076 1.1751088244642942 1.1786440266392897 1.0 13.131091168392198 -5.946137951404552 2.1972325680859144 1.1659280003265977 1.4930043968866706 0.4773493451894516 0.14641631864641202 0.2605173923177408 2.5443599323631805 0.04419684686875489 0.07182893062895795 1.1320407192172245e-06 5.946137951404552 0.3270763965600729 ENS(ph)SPENKNWLLAMAAK ddPTM_PC-9_Lapatinib_30min_R1 1 ENSSPENKNWLLAMAAK 17 1 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 ENS(0.598)S(0.402)PENKNWLLAMAAK 67.64399999999999 0.036711 0.0 11309.0 11035.0 12243.0 9546.9 10642.0 10747.0 9207.7 10197.0 11357.0 10492.0 True False 11147.731586183394 11009.449135488374 11236.427799346682 10249.0108735248 10016.058482977 10287.37586248061 9684.429652377883 10670.78984597868 10077.855065488144 12305.528220288783 0.9059124798725448 0.8946750548535175 0.9131203145607827 0.8328785802649826 0.8139478699063879 0.8359962838100086 0.7869982888187316 0.8671541485220583 0.8189697252387951 1.0 13.587018967002978 -5.762498341607481 24.996777900703293 0.8404971320695461 0.9035798689089196 0.14847936453216337 0.05516904875121001 40.91317381068 965799.8611686912 0.014170155249362049 0.022444986575536247 1.7278325783792865e-06 5.762498341607481 0.06308273683937349 ENS(ph)SSQDPQTEGTR ddPTM_PC-9_AZD4547_30min_R2 1 ENSSSQDPQTEGTR 14 0 A0A0C4DG49;P15151-3;P15151-2;P15151 A0A0C4DG49 PVR Poliovirus receptor 1 ENS(0.483)S(0.483)S(0.027)QDPQT(0.006)EGTR 114.58 0.00017147 5289400.0 9054.2 17901.0 9823.3 9638.6 9933.1 9068.2 11614.0 14474.0 9808.0 7568.3 True False 11933.24726094065 23687.14817686565 9693.036623569804 7416.5696848855405 8554.060522786636 8501.164020471946 12647.62350070077 12237.375879431744 10326.430856571149 7303.336120611238 1.633944688272395 3.2433326065900965 1.3272066988967455 1.0155043616238255 1.17125384639571 1.1640110601619769 1.7317597453863665 1.675587112154926 1.4139333978383155 1.0 12.83433991375313 -5.2947171312602 23.86364842383212 1.3305670306457262 2.4386384952036355 0.5236555381693686 0.4293810954152893 236.7195898783351 169752.42736785224 0.10870395450302806 0.22631657661508356 5.073210337635682e-06 5.2947171312602 1.1080714645579093 ENS(ph)SSQDPQTEGTR ddPTM_PC-9_Lapatinib_30min_R1 2 ENSSSQDPQTEGTR 14 0 A0A0C4DG49;P15151-3;P15151-2;P15151 A0A0C4DG49 PVR Poliovirus receptor 1 ENS(0.897)S(0.1)S(0.003)QDPQTEGTR;ENS(0.759)S(0.231)S(0.01)QDPQTEGTR 188.0 3.9329e-06 6005300.0 30714.0 37705.0 10710.1 5430.299999999999 10117.9 7059.9 8986.7 7073.8 13462.3 5163.5 True False 30276.012727742233 37617.696389088305 9829.55692018156 5829.6623769497655 9522.785014556755 6757.964534430706 9451.987353739196 7402.474572176519 11946.034009696314 6056.004095068732 4.999338219139467 6.211636550860253 1.6231093582293887 0.962625236944065 1.5724535295989885 1.115911486904965 1.5607630386901055 1.2223364541982704 1.972593449767265 1.0 12.564150465536153 -5.268979773310237 23.56561808968169 1.3758377436467335 5.605487560291321 0.9461132461072882 0.4034937974657033 40.93957696849392 127947.39802197446 0.09617910953425031 0.20717129345054663 5.382948523016317e-06 5.268979773310237 4.229649816644588 ENSFGS(ph)PLEFR ddPTM_PC-9_AZD4547_30min_R2 4 ENSFGSPLEFR 11 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 ENS(0.018)FGS(0.982)PLEFR;ENS(0.03)FGS(0.97)PLEFR;ENSFGS(1)PLEFR;ENSFGS(1)PLEFR 166.79 0.00061064 135160000.0 70290.0 82073.0 95326.0 76936.0 77418.0 99416.0 99354.0 117146.0 95193.0 86215.0 True False 92640.75787717501 108601.49222500942 94061.91495509807 59199.59384935087 66669.8470319535 93199.50180402267 108196.31352579854 99043.77744727863 100224.70763963883 83196.63909180368 1.1135156286175236 1.3053591276105836 1.1305975335290295 0.7115623238581409 0.8013526478922589 1.1202315721093168 1.3004889945903808 1.1904781073907127 1.2046725532872242 1.0 16.344237628306146 -6.993154702813995 24.949956227594203 1.1927227103207743 1.0128132428923502 0.16398625260913013 0.17145505411682127 316.0584720082954 1151972.6431255348 0.06820659406533439 0.060022629714193726 1.0158867528948789e-07 6.993154702813995 -0.17990946742842406 ENSFGS(ph)PLEFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ENSFGSPLEFR 11 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 ENS(0.001)FGS(0.999)PLEFR;ENS(0.001)FGS(0.999)PLEFR;ENS(0.001)FGS(0.999)PLEFR;ENS(0.006)FGS(0.994)PLEFR 140.33 8.0416e-05 105277600.0 64156.4 122069.2 99568.3 71975.6 86534.3 69878.3 86685.1 52195.8 58629.1 58752.3 True False 75016.81137334039 134187.42344876172 101942.38588688074 67943.04048004361 69578.52510667032 66213.75893428341 78473.65978222413 50825.71555602152 59486.439672140026 69403.62690704921 1.0808773938256684 1.9334353178469486 1.4688336968817206 0.9789551858873062 1.0025200152703164 0.9540388865118257 1.130685286625182 0.7323207420282417 0.8571085161271029 1.0 16.08272343693642 -5.742870286257038 4.597669426474826 0.9462327244411284 1.550524015689108 0.5720943571945991 0.21494185325232695 0.1242471461180095 6.360788864063498 0.057883540943291886 0.0977096413541301 1.8077139678476238e-06 5.742870286257038 0.6042912912479796 ENSFGS(ph)PLEFR ddPTM_PC-9_Lapatinib_30min_R1 5 ENSFGSPLEFR 11 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 ENSFGS(1)PLEFR;ENS(0.188)FGS(0.812)PLEFR;ENS(0.007)FGS(0.993)PLEFR;ENSFGS(1)PLEFR;ENS(0.343)FGS(0.657)PLEFR 152.11 0.00010477 156550200.0 70969.7 93425.6 91255.2 79952.5 105463.5 90722.9 100841.9 99008.5 96374.2 89126.8 True False 69957.65906375094 93209.27876325154 83752.54971125862 85832.47356372132 99260.3442792186 86842.89305240927 106063.0001587939 103608.79635829953 85519.52273068305 104532.2486260042 0.6692447544493725 0.8916796489926853 0.8012125522230823 0.8211099894235797 0.9495667182512504 0.8307760924871714 1.0146438209539186 0.9911658624028207 0.8181161685008332 1.0 16.67358856272869 -2.8204738537238216 0.2986633379698689 0.9653439302902636 2.9647561790123157e-13 0.4891834218352049 0.07502561478688996 22.58093455542031 0.6420114177267262 0.07767887305177477 9.977441529285144 0.001511910719732819 2.8204738537238216 -0.9653439302899671 ENSLCGS(ph)APNSR ddPTM_PC-9_AZD4547_30min_R2 1 ENSLCGSAPNSR 12 0 Q2NKX8;B5MDQ0 Q2NKX8 ERCC6L DNA excision repair protein ERCC-6-like 1 ENS(0.025)LCGS(0.911)APNS(0.063)R 78.249 0.01668 10932000.0 15168.0 20252.0 18240.0 25555.0 21013.0 22553.0 21324.0 24554.0 28713.0 22437.0 True False 19991.108486000718 26798.062950554882 17998.12568219573 19663.68957081422 18095.707660782202 21142.75734475462 23221.794689938284 20759.743494788385 30230.710561248707 21651.48745929129 0.9233133993028246 1.237700781571709 0.8312650904948429 0.9081911627450774 0.8357720315893032 0.9765036875414138 1.0725265288862698 0.9588137320274395 1.3962417417319668 1.0 14.402178521195578 -8.220762912897504 24.675046220978157 1.1981210478841857 0.9698072362725695 0.29326543648691317 0.14286541357857346 464.08247426428056 281521.15804879233 0.09435700949092714 0.03566265452521471 6.015020157764439e-09 8.220762912897504 -0.22831381161161624 ENSLCGS(ph)APNSR ddPTM_PC-9_Lapatinib_30min_R1 1 ENSLCGSAPNSR 12 0 Q2NKX8;B5MDQ0 Q2NKX8 ERCC6L DNA excision repair protein ERCC-6-like 1 ENS(0.006)LCGS(0.978)APNS(0.016)R 73.593 0.02229 8499300.0 2498.2 7039.1 8396.3 8045.3 11515.0 8157.0 11034.0 11144.0 13022.0 12810.0 True False 2462.575209886229 7022.801396431014 7705.988624655279 8636.978200334042 10837.710339361045 7808.144124895722 11605.286530223355 11661.790923172146 11555.325232260853 15024.191431747922 0.1639073371151616 0.46743290168620927 0.5129053806098076 0.5748714158475823 0.7213506556139627 0.5197047814763711 0.7724400067014582 0.776200900803845 0.7691146165671893 1.0 13.874999729967001 -5.631045912895076 0.25396311749990785 0.9758059564344372 1.3385035208224089e-21 0.8332042521610113 0.08936531402697138 2.6513038433189284 0.21102841118258908 0.14039703884499435 0.7986093269953832 2.3385899937201537e-06 5.631045912895076 -0.9758059564344372 down ENSLCGSAPNS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENSLCGSAPNSR 12 0 Q2NKX8;B5MDQ0 Q2NKX8 ERCC6L DNA excision repair protein ERCC-6-like 1 ENSLCGS(0.004)APNS(0.996)R 86.539 0.009067 6690600.0 29282.0 18672.0 25779.0 22858.0 36623.0 30632.0 25005.0 31452.0 23507.0 18810.0 True False 34238.86425413758 20525.63276105097 26393.669127401914 21577.34036663586 29446.986050405238 29025.60399544591 22636.34537947714 30626.418326148614 23850.74540412516 22220.104100121927 1.5408957626778041 0.9237415211271823 1.1878283291776786 0.9710728747898828 1.3252406882397845 1.3062766882035732 1.0187326430821235 1.3783201999481434 1.073385853489061 1.0 14.439577955249355 -8.514278768088397 24.19999427333136 0.9999999476899122 1.1919039072821629 0.12234089213898947 0.18387182678352793 697.3798855251024 1962396.8553615871 0.16694962976308367 0.04310620914240024 3.0599986290776834e-09 8.514278768088397 0.1919039595922507 ENSPS(ph)SQSAGLSSINK ddPTM_PC-9_Lapatinib_30min_R1 2 ENSPSSQSAGLSSINK 16 0 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2 H3BSS6 ZNF106 Zinc finger protein 106 1 ENS(0.288)PS(0.673)S(0.039)QSAGLSSINK;ENS(0.21)PS(0.688)S(0.006)QS(0.095)AGLS(0.001)SINK 183.71 9.6707e-30 0.0 19538.6 42436.0 36844.0 33838.0 39961.0 36413.0 38263.0 46150.0 39519.0 36206.0 True False 19259.975981059593 42337.74204926008 33814.828541952884 36326.55940025896 37610.57254634881 34855.70087284882 40244.07091770311 48294.29747885808 35067.95406648109 42464.158858537485 0.45355840074970294 0.9970229762539617 0.7963145732993687 0.8554640048629021 0.885701578868956 0.8208263582699232 0.9477185466399972 1.1372955164316987 0.825824766323627 1.0 15.373958052506486 -4.755087388816962 24.99916650824558 0.9138070562045935 0.4535576353815234 0.6606109560566216 0.09991789542590193 135.54152470975995 533393.010428866 0.02539397872069135 0.2330966387854655 1.757569919826346e-05 4.755087388816962 -0.4602494208230701 ENSQLDT(ph)SPPCLGGNKK ddPTM_PC-9_AZD4547_30min_R2 1 ENSQLDTSPPCLGGNKK 17 1 Q9Y3E2 Q9Y3E2 BOLA1 BolA-like protein 1 1 ENS(0.034)QLDT(0.483)S(0.483)PPCLGGNKK 74.51899999999999 0.0081176 12543000.0 15852.0 16279.0 18849.0 22520.0 23530.0 22993.0 20358.0 24036.0 20225.0 24092.0 True False 20892.60625791691 21540.868396804428 18599.049944282193 17328.36193053164 20263.265657364725 21555.244075198105 22169.822561328267 20321.788492332544 21294.05220984416 23248.546413034084 0.89866290505817 0.9265468908941222 0.8000091538563807 0.7453524888255659 0.8715927997117408 0.9271652383012365 0.9536003742969048 0.8741100682724542 0.9159304771805367 1.0 14.504852895844758 -6.652429065503562 4.3898099442432645 0.9274123323935632 0.8417796156567462 0.3790282439785584 0.05527656806924843 0.27452530207582304 9.262040619656922 0.020377290885201734 0.020211631637195155 2.2262346320439732e-07 6.652429065503562 -0.08563271673681705 ENSQLDT(ph)SPPCLGGNKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENSQLDTSPPCLGGNKK 17 1 Q9Y3E2 Q9Y3E2 BOLA1 BolA-like protein 1 1 ENS(0.001)QLDT(0.651)S(0.349)PPCLGGNKK 67.227 0.016184999999999998 13266000.0 26965.0 27161.0 21744.0 31329.0 35364.0 35731.0 32382.0 26456.0 23708.0 25512.0 True False 31529.641916973545 29857.364579204426 22262.4594245792 29573.73769998843 28434.67806259813 33857.203459169396 29314.542534622233 25761.558032449077 24054.684648870538 30137.123647119133 1.0462060774664381 0.9907171277793311 0.7387055143435134 0.9813059151321974 0.9435100175963959 1.1234384493891763 0.9727053874772972 0.8548114390110907 0.7981745348537923 1.0 14.87925410909106 -7.757693269741531 24.506504554637047 0.8698697251434362 0.9679785697483363 0.12395615806292959 0.10318430590401655 146.60089874064624 959068.7428283193 0.05283335439693076 0.028981334339131977 1.7470556146619708e-08 7.757693269741531 0.0981088446049001 ENSQLDT(ph)SPPCLGGNKK ddPTM_PC-9_Lapatinib_30min_R1 1 ENSQLDTSPPCLGGNKK 17 1 Q9Y3E2 Q9Y3E2 BOLA1 BolA-like protein 1 1 ENS(0.002)QLDT(0.594)S(0.404)PPCLGGNKK 76.176 0.0072101 13250000.0 85192.0 77042.0 79152.0 77453.0 72262.0 86588.0 69302.0 62471.0 80594.0 62495.0 True False 83977.1464577004 76863.61398244626 72644.42809555566 83149.15199563385 68011.6912325581 82884.83308648657 72890.11846270967 65373.63072159792 71516.65502755581 73297.17748064703 1.1457077795372577 1.048657214702993 0.9910944812948121 1.1344113764488144 0.9278896346385987 1.1308052497433616 0.9944464571225154 0.8918983372703375 0.9757081716610255 1.0 16.16147002384203 -7.51733100797733 24.60505266400108 0.9489164141270444 1.0567917384687389 0.33421303108278444 0.06854583500509466 224.30369153406133 994838.115026067 0.029577147531176285 0.017755440446260616 3.0385682250833114e-08 7.51733100797733 0.10787532434169445 ENSQLDTS(ph)PPCLGGNKK ddPTM_PC-9_AZD4547_30min_R2 1 ENSQLDTSPPCLGGNKK 17 1 Q9Y3E2 Q9Y3E2 BOLA1 BolA-like protein 1 1 ENSQLDT(0.459)S(0.54)PPCLGGNKK 86.213 0.0014227 15997000.0 60324.0 64293.0 63706.0 101500.0 91759.0 84390.0 59180.0 88653.0 63989.0 74989.0 True False 79505.77718285256 85074.45493185989 62861.216815239066 78100.74315936776 79019.84672563257 79113.07995937749 64446.90535314891 74953.71589327483 67371.32790386742 72363.65793487514 1.0986975983774214 1.1756516649341309 0.8686848980438778 1.079281304845808 1.0919824809954712 1.0932708795701924 0.8905976728145634 1.0357922475496009 0.9310105352122934 1.0 16.142977716628565 -7.242422844143368 24.97768322208339 0.9673327936076924 1.0653775860098418 0.27823543229014536 0.08160834123796844 1176.123429450556 1544806.8989668556 0.03154588533954101 0.02439493308577061 5.722386083462125e-08 7.242422844143368 0.09804479240214936 ENSS(ph)SQDPQTEGTR ddPTM_PC-9_AZD4547_30min_R2 1 ENSSSQDPQTEGTR 14 0 A0A0C4DG49;P15151-3;P15151-2;P15151 A0A0C4DG49 PVR Poliovirus receptor 1 ENS(0.204)S(0.685)S(0.112)QDPQTEGTR 195.45 1.2946e-07 3292600.0 4802.1 13174.0 9531.5 7450.5 9078.9 7438.4 9649.6 13299.0 8625.9 4856.8 True False 6329.067910114982 17432.237868388802 9405.106082228533 5732.902334077535 7818.451448221355 6973.275672115582 10508.395706247817 11243.94513061784 9081.84746387613 4686.764910294868 1.3504129247474432 3.7194606945395203 2.006737325691211 1.2232109874947512 1.6681979143113148 1.4878654691636448 2.242142694882189 2.399084516895563 1.9377646708771543 1.0 12.194376715225157 -5.506445133373013 24.521673747030857 1.7654629323583737 2.6169774225702347 0.18939114396215428 0.6666734056082234 808.6912232441307 1206698.5728052927 0.1699887345489821 0.33918920572655187 3.1156944926155897e-06 5.506445133373013 0.851514490211861 ENSSALS(ph)PNHR ddPTM_PC-9_AZD4547_30min_R2 1 ENSSALSPNHR 11 0 A0AVK6 A0AVK6 E2F8 Transcription factor E2F8 1 ENSSALS(1)PNHR 79.652 0.017847 0.0 4730.5 4281.2 25234.0 29658.0 23345.0 21744.0 20794.0 31119.0 20961.0 29554.0 True False 6234.700599487504 5665.014176570989 24899.3806723973 22820.80631153231 20103.94971403229 20384.34424264373 22644.625716684335 26310.273593480473 22068.955667270377 28519.323455537495 0.2186132012986772 0.19863774768019726 0.8730705239630316 0.8001875060995276 0.7049237947518274 0.714755533188701 0.7940099193442651 0.9225419962889022 0.7738246561730877 1.0 14.799652137666525 -5.258376351829057 24.978659714552492 0.8102271694513598 0.20862540273685176 0.889728278051012 0.08641165321236974 74.97619484238403 611414.8422337299 0.022433737592805845 0.05432225014279393 5.515992260832484e-06 5.258376351829057 -0.6016017667145079 ENSSALS(ph)PNHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ENSSALSPNHR 11 0 A0AVK6 A0AVK6 E2F8 Transcription factor E2F8 1 ENSS(0.001)ALS(0.999)PNHR;ENSSALS(1)PNHR;ENSSALS(1)PNHR 68.751 0.020646 5109800.0 29357.9 40723.7 53670.0 61698.9 80250.0 70978.0 69682.0 79285.0 78201.0 63245.0 True False 34327.612625044254 44766.479802442715 54949.69634460842 58242.110663532665 64525.58857944515 67255.78873037206 63081.216506007906 77203.85275940158 79344.54168324295 74710.81785285541 0.45947312064838103 0.5991967574309155 0.7354985251644955 0.7795673014615069 0.8636712919744729 0.9002148639683454 0.8443384548439523 1.033369128838293 1.0620221269631094 1.0 16.189029534648363 -4.652373420114521 0.36567723025956866 1.0340950993369038 6.453995409421972e-18 0.9335227011014715 0.04700366688601239 1.729175878786894 0.17166717030489545 0.04599477377622721 0.807759952209711 2.2265198938512088e-05 4.652373420114521 -1.0340950993369038 down ENSSALS(ph)PNHR ddPTM_PC-9_Lapatinib_30min_R1 2 ENSSALSPNHR 11 0 A0AVK6 A0AVK6 E2F8 Transcription factor E2F8 1 ENSSALS(1)PNHR;ENSS(0.001)ALS(0.999)PNHR 102.72 0.0018155 5362300.0 28149.0 33381.0 47884.0 37265.0 52083.0 46470.0 39529.0 41767.0 52802.0 43351.0 True False 27747.590098105607 33303.708345422536 43947.162357585265 40005.59241239583 49019.58033911775 44482.586426860864 41575.61820311756 43707.64729792988 46854.882730290105 50844.162588423475 0.5457379704080987 0.6550153773799263 0.8643502050241543 0.786827639118292 0.9641142236115585 0.8748808941341271 0.8177068140479861 0.8596394369150553 0.9215390783318422 1.0 15.633794527513125 -4.987622695904931 1.2704636152516533 0.8881945588880072 0.4521036200582234 0.79481550302536 0.05953930498611762 0.4282955020913613 0.7823621566534699 0.01769418772297743 0.22227824157751647 1.028909800834794e-05 4.987622695904931 -0.43609093882978384 ENSSS(ph)QDPQTEGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENSSSQDPQTEGTR 14 0 A0A0C4DG49;P15151-3;P15151-2;P15151 A0A0C4DG49 PVR Poliovirus receptor 1 ENS(0.201)S(0.015)S(0.732)QDPQT(0.019)EGT(0.032)R 73.296 0.020808 2286000.0 12582.0 9350.4 7292.6 5516.7 14153.0 5178.9 7227.8 4563.8 5293.0 6627.3 True False 14711.884094172485 10278.645917359194 7466.4832413395125 5207.617184382719 11379.8212481606 4907.309367067599 6543.130459259543 4444.005085745804 5370.400111627795 7828.777028322062 1.8792059144039355 1.3129312381964993 0.953722811919169 0.6651891049576699 1.4535886265494564 0.6268296247695511 0.8357793861785242 0.5676499751709349 0.6859819984908716 1.0 12.934571239307575 -1.52287874776045 0.6639303150372817 0.787225372478626 109.48566494215684 0.6458444050294964 0.24119448633135757 145.6411712888577 0.891242172416133 0.09989719877228023 23339.359310246204 0.029999999828679905 1.52287874776045 108.69843956967821 ENTQTTIK ddPTM_PC-9_Lapatinib_30min_R1 1 ENTQTTIK 8 0 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 125.82 0.015986 11501000.0 43580.0 39189.0 31399.0 34057.0 42417.0 40166.0 40117.0 41066.0 43421.0 37109.0 False True 42958.54120840679 39098.26027826497 28817.49542364507 36561.66539082154 39922.11545503062 38448.19381151915 42194.06196601145 42974.076278803586 38530.469736599516 43523.24120536566 0.987025322992506 0.8983306205017846 0.6621174026922511 0.8400492329673765 0.9172597065245434 0.8833945438507268 0.9694604720939225 0.9873822603429091 0.8852849344283068 1.0 15.409498378619046 -6.7916067879580995 1.5986995696423147 0.9570882587823065 0.8424180340193218 0.24505688840189677 0.08284762609156818 0.5645419514235817 2.991966446878433 0.03903044742113269 0.034631108311249034 1.6158208657120465e-07 6.7916067879580995 -0.11467022476298472 ENVEYIEREES(ph)DGEYDEFGR ddPTM_PC-9_AZD4547_30min_R2 4 ENVEYIEREESDGEYDEFGR 20 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 ENVEYIEREES(0.986)DGEY(0.014)DEFGR;ENVEYIEREES(0.778)DGEY(0.222)DEFGR;ENVEYIEREES(0.992)DGEY(0.008)DEFGR;ENVEYIEREES(0.997)DGEY(0.003)DEFGR 96.777 0.00022437 307070400.0 200295.1 153963.7 241386.1 324550.0 283211.0 240380.2 186185.9 251970.1 239693.1 247046.9 True False 263984.77540310886 203729.45510074816 238185.162595124 249730.0117475154 243892.04122770604 225349.18809398182 202756.08441011925 213033.91074188225 252362.78792283777 238397.86322622458 1.1073286137325984 0.8545775215586632 0.9991077913693432 1.0475346060905644 1.0230462552269934 0.9452651338579307 0.8504945542138374 0.8936066282596101 1.0585782292996533 1.0 17.863011779336112 -6.8485129513367164 6.7380109908964005 0.9359655999291452 0.9996260339118508 0.09826035844452286 0.07984380257646642 0.4867116464769164 31.237500883863913 0.028438445734510858 0.025129356063820284 1.4173824422642888e-07 6.8485129513367164 0.0636604339827056 ENVEYIEREES(ph)DGEYDEFGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ENVEYIEREESDGEYDEFGR 20 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 ENVEYIEREES(0.998)DGEY(0.002)DEFGR;ENVEYIEREES(0.991)DGEY(0.009)DEFGR;ENVEYIEREES(1)DGEYDEFGR;ENVEY(0.02)IEREES(0.96)DGEY(0.02)DEFGR;ENVEYIEREES(0.999)DGEYDEFGR 112.74 1.7071e-05 281238000.0 219958.0 185562.0 262385.2 326781.5 350476.5 305909.9 330888.5 286992.8 285647.9 219764.1 True False 257192.54503147354 203983.36902346511 268641.4582694126 308472.99199491704 281803.1457416069 289867.44632039865 299544.34585471335 279459.5430940065 289824.9601447652 259605.59167834182 0.9907049511866519 0.7857433567001357 1.0348061323820268 1.1882370868849512 1.0855049150511689 1.1165685779201246 1.153843967374388 1.076477364325281 1.1164049212925504 1.0 17.985961932503194 -5.474982791524621 6.160803708231547 1.1104679090938514 0.8909422334344776 0.6303360824634124 0.06563607103675202 0.11346153725480485 10.517321758243403 0.015895462893804953 0.03279679289601445 3.3497871208427617e-06 5.474982791524621 -0.21952567565937375 ENVEYIEREES(ph)DGEYDEFGR ddPTM_PC-9_Lapatinib_30min_R1 5 ENVEYIEREESDGEYDEFGR 20 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 ENVEYIEREES(1)DGEYDEFGR;ENVEY(0.004)IEREES(0.996)DGEYDEFGR;ENVEY(0.006)IEREES(0.992)DGEY(0.002)DEFGR;ENVEY(0.004)IEREES(0.993)DGEY(0.004)DEFGR;ENVEYIEREES(0.998)DGEY(0.002)DEFGR 109.68 3.8261e-05 256835800.0 185287.4 164874.5 192911.7 157718.2 172257.8 187904.2 148553.0 153907.0 205259.9 151059.7 True False 182645.1676984519 164492.74322510872 177051.24468669711 169317.3225604918 162125.9348758649 179867.97539208434 156244.3474645884 161058.08108512708 182141.36857943 177170.16787060208 1.0309024927483759 0.9284449250239891 0.9993287629326411 0.9556762551817094 0.9150859697456241 1.0152272109571665 0.8818885783226382 0.9090586921086928 1.02805890386952 1.0 17.43477617602506 -5.902233923467905 8.107140876707 0.9511630549876477 0.980301965737868 0.04747793609498219 0.050880523232952876 0.7542758531087056 55.460855398172555 0.013984744094296463 0.02081159089063355 1.2524663789004167e-06 5.902233923467905 0.029138910750220237 ENVEYIEREES(ph)DGEYDEFGRK ddPTM_PC-9_Lapatinib_30min_R1 1 ENVEYIEREESDGEYDEFGRK 21 2 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 ENVEY(0.054)IEREES(0.486)DGEY(0.46)DEFGRK 42.226000000000006 0.032666 6014400.0 15124.0 13211.0 18581.0 15773.0 16431.0 16291.0 18813.0 17663.0 18658.0 11936.0 True False 14908.328986598084 13180.41074118142 17053.341904734196 16932.99903718555 15464.560884588911 15594.271906175829 19787.04508728403 18483.68746195168 16556.539562549777 13999.121696279719 1.0649474524219606 0.9415169770746494 1.2181722735695726 1.2095758151517113 1.1046807949886337 1.1139464492490285 1.413449037488006 1.3203462233536936 1.1826841656037388 1.0 13.77304869499323 -5.270743556631604 24.35630873404313 1.208948673992592 1.003232215682652 0.313348542822791 0.11232961192744928 463.33629572339095 1212916.3055163221 0.030347103109462575 0.06460528828470857 5.361131295845823e-06 5.270743556631604 -0.20571645830994 ENVEYIEREESDGEY(ph)DEFGRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENVEYIEREESDGEYDEFGRK 21 2 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 ENVEY(0.006)IEREES(0.314)DGEY(0.68)DEFGRK 57.41 0.020649 4821800.0 7328.1 6370.6 7962.1 11952.0 13642.0 9124.4 7865.8 9385.0 8121.9 6149.1 True False 8568.602593427551 7003.031066171343 8151.946660432405 11282.368188906818 10968.948029916399 8645.900401411807 7120.694480539545 9138.653694229462 8240.667422374796 7263.883153751181 1.179617349571846 0.9640891680030493 1.1222574052864016 1.5532144378011405 1.5100666954219748 1.190258738805143 0.9802875858296686 1.2580948097313653 1.1344713630366132 1.0 12.826525280399458 -7.00080764407219 24.999985987915508 1.1105144423254372 1.2663810710286647 0.17208914643296291 0.1768791700178276 68.27881053078835 2113581.0343751507 0.07131605622577382 0.062147565113969294 9.981420589122927e-08 7.00080764407219 0.15586662870322754 ENVEYIEREESDGEY(ph)DEFGRK ddPTM_PC-9_Lapatinib_30min_R1 1 ENVEYIEREESDGEYDEFGRK 21 2 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 ENVEY(0.002)IEREES(0.452)DGEY(0.546)DEFGRK 59.153999999999996 0.017031 15767000.0 6256.3 7795.5 9457.2 7142.0 7446.8 7114.0 5365.3 5928.1 7678.7 5729.5 True False 6167.084014735091 7777.449998704094 8679.66552184771 7667.24650501358 7008.793864972105 6809.750803543967 5643.088981385482 6203.541167593035 6813.843945704299 6719.83644092114 0.9177431726135467 1.1573868005689105 1.2916483307528124 1.140987071995248 1.0430006632737858 1.013380439154037 0.8397658233199409 0.9231684762170592 1.0139895525151015 1.0 12.714210403269751 -6.6533016279657495 2.133647843750844 0.9398105375640712 1.1383800258341323 0.3985526268196936 0.0976804674535048 0.30456949359862723 2.83717773096252 0.038846723965182774 0.03841686763328662 2.2217662845427607e-07 6.6533016279657495 0.19856948827006116 ENVPNSDSQPPPSCLTTAVPS(ph)PSKPR ddPTM_PC-9_AZD4547_30min_R2 1 ENVPNSDSQPPPSCLTTAVPSPSKPR 26 1 Q8IY92 Q8IY92 SLX4 Structure-specific endonuclease subunit SLX4 1 ENVPNSDSQPPPS(0.006)CLT(0.026)T(0.075)AVPS(0.713)PS(0.181)KPR 76.47800000000001 0.00040031 0.0 10675.0 10525.0 13440.0 13602.0 14701.0 14660.0 12551.0 14091.0 13297.0 14137.0 True False 14069.427946206346 13927.00042240718 13261.776818460008 10466.269048805127 12660.019907731355 13743.307882503554 13668.014685491255 11913.559728967304 13999.852273636485 13642.067932967908 1.0313266299023234 1.0208863121661118 0.9721236460354464 0.7672054632943124 0.9280132579560537 1.0074211585833688 1.001901966230548 0.8732957340123318 1.0262265473553274 1.0 13.735774731426723 -9.605564751678697 17.96287707182006 0.9999999995571491 0.9545896966140709 0.021396634671692283 0.079486197861467 0.0 0.0 0.08093237723144847 0.019628984697505642 2.479906165417913e-10 9.605564751678697 -0.04541030294307824 ENVPNSDSQPPPSCLTTAVPS(ph)PSKPR ddPTM_PC-9_Lapatinib_30min_R1 2 ENVPNSDSQPPPSCLTTAVPSPSKPR 26 1 Q8IY92 Q8IY92 SLX4 Structure-specific endonuclease subunit SLX4 1 ENVPNSDSQPPPSCLT(0.002)T(0.009)AVPS(0.707)PS(0.281)KPR;ENVPNSDSQPPPS(0.001)CLT(0.003)T(0.013)AVPS(0.688)PS(0.295)KPR 91.706 1.5658e-07 11024900.0 49817.0 55495.0 61088.0 50801.0 59256.0 54429.0 46497.0 49716.0 57604.0 46721.0 True False 49106.60044468108 55366.504737102674 56065.58044649923 54537.07500716813 55770.67858177837 52101.198550196044 48904.387148431706 52025.98685718113 51116.03092298836 54796.66259818075 0.8961604250385755 1.0103992125049754 1.0231568454747573 0.9952627116560702 1.0177750968291626 0.9508097040918292 0.8924701766427529 0.9494371443509845 0.9328310977224625 1.0 15.741800407777662 -6.9191907605616505 6.635550565707223 0.9370269893269008 0.9917896846249697 0.20718543632875064 0.04158633728515661 0.2846289309185304 18.999484881900408 0.014557855204447658 0.012820541008667023 1.204506753691557e-07 6.9191907605616505 0.054762695298068986 ENVSDLTLGPGNS(ph)PITR ddPTM_PC-9_AZD4547_30min_R2 2 ENVSDLTLGPGNSPITR 17 0 Q6DCA0 Q6DCA0 AMMECR1L AMMECR1-like protein 1 ENVSDLT(0.003)LGPGNS(0.952)PIT(0.045)R;ENVSDLT(0.006)LGPGNS(0.994)PITR 120.99 7.7895e-05 22840000.0 40034.0 41260.0 55435.0 62962.0 52665.0 53829.0 41684.0 56102.0 47968.0 44732.0 True False 52763.97924107022 54596.48811672406 54699.89567941446 48447.08365320309 45353.37381407194 50463.06412055139 45393.795247392016 47432.72499570814 50503.49055138712 43165.946295361144 1.2223519642088916 1.2648046157299535 1.2672001977005847 1.1223449920848714 1.0506748422412293 1.1690480216803316 1.0516112617290239 1.0988459437713178 1.169984556942622 1.0 15.39760599553215 -5.821391176483633 4.992277371152441 1.096483008243889 1.2530701791416026 0.6702113082672232 0.050604194198996644 0.11197856707860904 5.567203697179127 0.013678206414974399 0.02113192771344677 1.5087206114602273e-06 5.821391176483633 0.15658717089771357 ENVSDLTLGPGNS(ph)PITR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ENVSDLTLGPGNSPITR 17 0 Q6DCA0 Q6DCA0 AMMECR1L AMMECR1-like protein 1 ENVSDLT(0.001)LGPGNS(0.994)PIT(0.005)R;ENVSDLT(0.122)LGPGNS(0.647)PIT(0.23)R;ENVSDLTLGPGNS(0.995)PIT(0.005)R 169.51 1.6185e-05 12140800.0 61708.9 70865.0 81057.0 75571.0 86041.0 73283.0 97127.0 75295.0 72545.0 74776.0 True False 72154.99796366884 77900.0088695308 82989.7062903842 71337.00187448766 69181.8837004866 69439.91047265161 87926.4274214146 73318.58603164712 73605.83338334368 88332.29687350956 0.8168586181676407 0.8818972406104458 0.9395171327790122 0.8075981764251088 0.7832003259187742 0.7861214179915241 0.995405197572569 0.8300314678405585 0.8332833628083515 1.0 16.430653405419186 -10.561747673411814 5.441992797752425 1.0000008571397936 0.8542796993963975 0.3159549700692037 0.06500054485685235 6.996056791689393e-07 1.23516114542424e-07 0.06513870833289459 0.015798364470162085 2.7431674987735917e-11 10.561747673411814 -0.1457211577433961 ENVSDLTLGPGNS(ph)PITR ddPTM_PC-9_Lapatinib_30min_R1 1 ENVSDLTLGPGNSPITR 17 0 Q6DCA0 Q6DCA0 AMMECR1L AMMECR1-like protein 1 ENVS(0.005)DLT(0.012)LGPGNS(0.982)PIT(0.001)R 97.256 0.0014719000000000002 9392400.0 9572.7 10476.0 12663.0 9185.2 10121.0 11150.0 11236.0 9177.0 8738.0 11246.0 True False 9436.191542581819 10451.743465643527 11621.897020593573 9860.710248928966 9525.70267865159 10673.140491919496 11817.745101829758 9603.396922285603 7753.834424780786 13189.856115646933 0.7154127732589746 0.7924076937613275 0.8811238666058446 0.7475980149041467 0.7221991350877125 0.809193094931347 0.8959722530870173 0.7280895893089564 0.5878634578570213 1.0 13.687141206278797 ENVSDLTLGPGNSPIT(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ENVSDLTLGPGNSPITR 17 0 Q6DCA0 Q6DCA0 AMMECR1L AMMECR1-like protein 1 ENVSDLT(0.001)LGPGNS(0.363)PIT(0.636)R 123.0 0.00012374 2250500.0 13955.0 15536.0 16389.0 16588.0 21288.0 17550.0 19744.0 19436.0 15157.0 13765.0 True False 16317.305876186398 17078.31140615293 16779.775915628627 15658.62813902161 17116.76921718665 16629.647104990723 17873.7053858187 18925.825594144244 15378.64245077319 16260.48553631996 1.003494381501679 1.0502952921058997 1.0319357240685563 0.9629865051720613 1.0526604005122766 1.0227029855809773 1.099211050364726 1.163915158121871 0.94576772731804 1.0 13.989082716321722 -7.1647194645085355 9.645399413258536 1.065850531570414 1.0212639093414433 0.04469656206161887 0.05928015869695662 0.9532529342385474 89.000047215375 0.022124466794566987 0.01713470341657529 6.843535674037232e-08 7.1647194645085355 -0.04458662222897081 ENYSHHTQDDR ddPTM_PC-9_AZD4547_30min_R2 3 ENYSHHTQDDR 11 0 Q92804-2;Q92804;A0A075B7D9;A0A075B7E4;A0A075B7F2 Q92804-2 TAF15 TATA-binding protein-associated factor 2N 0 ;; 129.0 0.00011842 5841750.0 2324.84 3411.0499999999997 23753.8 55243.7 31932.9 32000.399999999998 12001.7 40993.5 17978.5 27848.5 False True 3064.090760323966 4513.605205781663 23438.809091542797 42508.11847165677 27499.56803697672 29999.409929281486 13069.828049626349 34658.896511916886 18928.806806164794 26873.53249142371 0.1140189054528587 0.16795727198209293 0.8721893595128569 1.5817838047611572 1.0232956179375674 1.116318070162728 0.48634574013659687 1.2897037828196856 0.7043661570061786 1.0 14.713898353780793 -5.295562639093955 4.181180444661076 1.0337790369611362 0.1240564929261639 0.6080452559236966 0.28075454333473976 0.12885833883483527 5.178263594649461 0.07437842594257485 0.17913255636207853 5.0633431472512285e-06 5.295562639093955 -0.9097225440349722 ENYSHHTQDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ENYSHHTQDDR 11 0 Q92804-2;Q92804;A0A075B7D9;A0A075B7E4;A0A075B7F2 Q92804-2 TAF15 TATA-binding protein-associated factor 2N 0 ; 114.71 0.000602 3660600.0 4428.1 10300.1 29887.0 22170.6 32148.0 28398.0 22261.7 15925.6 19197.6 11318.2 False True 5177.689871038405 11322.625857010551 30599.619427078687 20928.453160054996 25848.83017634895 26908.75888817813 20152.91061524919 15507.569874568004 19478.328581708985 13370.100065178103 0.38725887209501847 0.8468617139597842 2.288660464611943 1.5653176160261002 1.9333310932856222 2.0126071425793537 1.507311876276577 1.1598693950658496 1.4568573523574084 1.0 13.706722642512203 -3.253469890728681 8.521570843726927 1.4663392816853533 1.252191496462652 0.0 0.5535187920309983 0.0 0.0 0.13323114672433958 0.0 0.0005578662772005308 3.253469890728681 -0.2141477852227014 ENYSHHTQDDR ddPTM_PC-9_Lapatinib_30min_R1 2 ENYSHHTQDDR 11 0 Q92804-2;Q92804;A0A075B7D9;A0A075B7E4;A0A075B7F2 Q92804-2 TAF15 TATA-binding protein-associated factor 2N 0 ; 150.09 0.00013744 2719200.0 5900.8 5543.0 20437.1 8875.8 13831.3 19395.8 15141.5 18953.8 27354.0 9231.0 False True 5816.653509925807 5530.165524060907 18756.84052748739 9528.555940800828 13017.770127382058 18566.286847818123 15925.452782071505 19834.462742248747 24273.104469610145 10826.56605046566 0.5372574722966409 0.510795897635802 1.732482898091278 0.8801087894707849 1.2023914200220625 1.7148823330754601 1.4709606635971648 1.832017894667132 2.2419947706841112 1.0 13.402288103792694 -5.134668488155375 0.5427688805809392 1.7066611973221664 5.444836229137711e-14 0.4607851396212588 0.4047213629016719 2.62983488267058 0.7759335098008259 0.24737604027985685 2.706976110741622 7.333841367459158e-06 5.134668488155375 -1.706661197322112 ENYSHHTQDDRR ddPTM_PC-9_AZD4547_30min_R2 6 ENYSHHTQDDRR 12 1 Q92804-2;Q92804;A0A075B7D9;A0A075B7E4;A0A075B7F2 Q92804-2 TAF15 TATA-binding protein-associated factor 2N 0 ;;;;; 131.42 4.6482e-05 24513350.0 12110.199999999999 13361.33 113715.92 305410.9 186926.01 131883.87 47073.340000000004 176809.24 75416.8 124993.4 False True 15960.991692191848 17680.11862745099 112207.97260013786 235003.13555636772 160974.56008929954 123637.15076030487 51262.77606685708 149487.43463014052 79403.17808155123 120617.41911102975 0.13232741845934845 0.14658014371188155 0.930279999581562 1.9483349692638057 1.3345879996082537 1.0250356181680145 0.42500309196360014 1.2393519587128254 0.6583060611540665 1.0 16.880078745276705 -5.29902813674696 4.620009065642795 1.1020849238649582 0.12798791534210324 0.4873998059188167 0.3834249055275311 0.1649692371443278 8.523972886318392 0.10911396849162132 0.25321082479024254 5.0231004517962705e-06 5.29902813674696 -0.9740970085228549 ENYSHHTQDDRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ENYSHHTQDDRR 12 1 Q92804-2;Q92804;A0A075B7D9;A0A075B7E4;A0A075B7F2 Q92804-2 TAF15 TATA-binding protein-associated factor 2N 0 ;;;; 108.68 0.00088744 9071290.0 2590.7799999999997 5629.91 35549.399999999994 22093.19 35099.380000000005 37577.43 22777.85 19103.989999999998 23831.32 16972.6 False True 3029.3478837625325 6188.810258021016 36397.03251785027 20855.38019138841 28221.908452007574 35606.80341951516 20620.167150646805 18602.530504850558 24179.807970571994 20049.598024972314 0.1510926992146874 0.3086750293104473 1.8153497378110417 1.0401894424722367 1.4076047019424742 1.7759360250098746 1.0284578835427938 0.9278256093553898 1.2059996385192058 1.0 14.291285691880894 -5.161298358731202 6.746034255952287 1.2766983214947003 0.20046028611825442 0.6646109280964174 0.2974456120773049 0.14281956026998574 8.209533120029947 0.07718051046615877 0.20899920206224687 6.89765774449641e-06 5.161298358731202 -1.0762380353764458 ENYSHHTQDDRR ddPTM_PC-9_Lapatinib_30min_R1 5 ENYSHHTQDDRR 12 1 Q92804-2;Q92804;A0A075B7D9;A0A075B7E4;A0A075B7F2 Q92804-2 TAF15 TATA-binding protein-associated factor 2N 0 ;;;; 143.0 3.2981e-05 9262340.0 32117.7 11895.8 91584.9 25519.8 50453.2 73301.59999999999 36401.9 43391.44 98775.0 28626.4 False True 31659.695708335177 11868.25600597577 84055.14304993748 27396.611223557185 47485.64197080766 70166.66144237533 38286.612266135366 45407.564710639665 87649.91935313815 33574.43509771965 0.9429703170340303 0.35349086206313723 2.503546010686162 0.8159961930504064 1.4143392683331504 2.08988360453877 1.1403501549527415 1.3524446376678936 2.610614865090947 1.0 15.03507550552906 -5.234339428561812 24.982256466003424 1.5926621950169728 0.6482304604832098 0.29703382318155014 0.5945971974273965 899.0512545568921 828793.0815606792 0.14402834555319938 0.3808513149120528 5.829892832318673e-06 5.234339428561812 -0.9444317345337631 EPAITSQNS(ph)PEAR ddPTM_PC-9_AZD4547_30min_R2 4 EPAITSQNSPEAR 13 0 A0A1W2PRL9;A0A1W2PPZ5;P23193-2;P23193;E5RIS7 A0A1W2PRL9 TCEA1 Transcription elongation factor A protein 1 1 EPAIT(0.018)S(0.014)QNS(0.968)PEAR;EPAITS(0.001)QNS(0.999)PEAR;EPAITSQNS(1)PEAR;EPAITS(0.001)QNS(0.999)PEAR 187.08 3.6395e-05 222182000.0 45470.2 55138.0 83780.0 90115.0 76988.0 69504.0 67900.0 88756.0 62068.0 62944.0 True False 59928.77776108585 72960.28021764247 82669.02245912045 69340.37901287118 66299.5451096131 65157.90389260074 73942.96846027045 75040.79960997954 65348.787765666566 60740.34971866252 0.9866386683426138 1.201183077733011 1.3610231558103842 1.141586759609425 1.0915239279441047 1.0727284942282926 1.2173615858775904 1.235435751647034 1.0758711148083513 1.0 15.890367594540296 -5.974652611019539 24.999011344886505 1.1289725864771916 1.1958605967999116 0.06177617754936182 0.10688654269850267 663.2426900195335 654122.7273131525 0.03097928928126149 0.04594804166648058 1.0601013534473011e-06 5.974652611019539 0.06688801032272007 EPAITSQNS(ph)PEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 EPAITSQNSPEAR 13 0 A0A1W2PRL9;A0A1W2PPZ5;P23193-2;P23193;E5RIS7 A0A1W2PRL9 TCEA1 Transcription elongation factor A protein 1 1 EPAIT(0.008)S(0.03)QNS(0.963)PEAR;EPAIT(0.007)S(0.023)QNS(0.971)PEAR;EPAITSQNS(0.999)PEAR;EPAITSQNS(1)PEAR;EPAIT(0.001)S(0.002)QNS(0.997)PEAR 199.33 5.5365e-07 171529000.0 52452.899999999994 78019.29999999999 80077.59999999999 76765.8 108368.6 59033.5 78146.2 70945.3 55327.6 47564.3 True False 61332.13997800193 85764.54049240911 81986.9536799891 72464.8611040815 87134.55076050415 55937.67933746261 70743.62620650651 69083.06104775889 56136.661480464354 56187.331071208384 1.0915652836450502 1.526403530071866 1.4591715270491112 1.2897010717993345 1.550786433512479 0.9955567967193639 1.2590672106644534 1.2295131256582956 0.9990982025702588 1.0 15.777957252679826 -6.765947144904987 24.99997900448155 1.1211428978770956 1.3904533161924855 0.4742416212591368 0.14983530977160395 107.91648254511716 598498.1413920539 0.05045098964033554 0.04599690264591644 1.7141659145549618e-07 6.765947144904987 0.2693104183153898 EPAITSQNS(ph)PEAR ddPTM_PC-9_Lapatinib_30min_R1 4 EPAITSQNSPEAR 13 0 A0A1W2PRL9;A0A1W2PPZ5;P23193-2;P23193;E5RIS7 A0A1W2PRL9 TCEA1 Transcription elongation factor A protein 1 1 EPAIT(0.016)S(0.017)QNS(0.966)PEAR;EPAITS(0.001)QNS(0.999)PEAR;EPAITSQNS(1)PEAR;EPAIT(0.007)S(0.091)QNS(0.902)PEAR 187.08 3.6395e-05 145502000.0 41833.5 85890.0 104391.0 90122.0 102504.0 85881.0 91243.0 76041.0 104198.0 72942.0 True False 41236.94661867564 85691.12698206594 95808.37494091298 96749.87251817886 96474.91625061784 82208.06982838911 95967.1160845721 79574.14246131857 92462.12398641655 85549.9275108944 0.48202199368812204 1.0016504920025042 1.1199118190802935 1.1309170601676803 1.1277030741882532 0.960936756117301 1.1217673571067739 0.9301485667674605 1.0807972218870896 1.0 16.384479011824425 -4.763341219876152 4.271595282567844 1.0605114099568078 0.4278565042350171 0.8609656987836476 0.06912706996000899 0.07500587021344107 2.7983515982615392 0.017358501875128718 0.1483779961136585 1.7244824547582125e-05 4.763341219876152 -0.6326549057217907 down EPALPLEPDSGGNT(ph)SPGVTANGEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EPALPLEPDSGGNTSPGVTANGEAR 25 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;Q5VY93 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 EPALPLEPDSGGNT(0.58)S(0.42)PGVTANGEAR 82.508 7.8457e-05 12826000.0 20251.0 26275.0 21114.0 18441.0 28522.0 25799.0 30127.0 23918.0 23829.0 18675.0 True False 23679.094324518137 28883.408354574432 21617.43783529091 17407.81055652867 22933.318846890175 24446.055023456163 27273.152459408444 23290.177843215784 24177.454044961007 22060.62966878133 1.0733643907738113 1.3092739775895075 0.9799102817941052 0.7890894692440713 1.039558670410202 1.1081304292075815 1.2362816868279836 1.0557349537567564 1.0959548484318768 1.0 14.429186349402759 -6.761254722330895 7.525676044199068 1.1114264641216616 1.0360784220390025 0.047431862458283014 0.13097322520478824 0.42407027511502743 156.93655839316784 0.04929095741128165 0.04628585954966173 1.7327873854681485e-07 6.761254722330895 -0.0753480420826591 EPALPLEPDSGGNT(ph)SPGVTANGEAR ddPTM_PC-9_Lapatinib_30min_R1 1 EPALPLEPDSGGNTSPGVTANGEAR 25 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;Q5VY93 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 EPALPLEPDS(0.002)GGNT(0.594)S(0.403)PGVT(0.001)ANGEAR 97.352 4.6289e-06 11844000.0 30339.0 24477.0 26621.0 24538.0 31046.0 27811.0 26797.0 28885.0 30703.0 21207.0 True False 29906.360296508792 24420.325010362412 24432.3241400317 26342.60637636841 29219.93531878443 26621.588360607457 28184.417541272003 30227.102549876814 27244.90482307673 24872.601693448734 1.2023816673905052 0.9818162696182503 0.982298693202931 1.0591013638636309 1.1747840326040662 1.0703178014393 1.1331511632213198 1.2152770716317312 1.0953781658576087 1.0 14.60226980201873 -6.090640047845396 7.445803098121021 1.1240075191011563 1.0436962242702457 0.10364305691012321 0.07928391048248837 0.47292365409030734 34.142358444763296 0.022973483951456923 0.029801475152855837 8.116334775943469e-07 6.090640047845396 -0.0803112948309106 EPALPLEPDSGGNTS(ph)PGVTANGEAR ddPTM_PC-9_AZD4547_30min_R2 4 EPALPLEPDSGGNTSPGVTANGEAR 25 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;Q5VY93 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 EPALPLEPDSGGNT(0.153)S(0.846)PGVTANGEAR;EPALPLEPDS(0.014)GGNT(0.244)S(0.729)PGVT(0.014)ANGEAR;EPALPLEPDSGGNT(0.051)S(0.949)PGVTANGEAR;EPALPLEPDSGGNT(0.091)S(0.908)PGVTANGEAR 166.46 1.4748e-10 31387000.0 78458.0 71605.8 108164.0 155832.0 119397.0 104887.0 92810.0 120651.0 93745.0 104817.0 True False 103406.0119722207 94750.97452226176 106729.67468689785 119907.33998040007 102820.78749223852 98328.3993091509 101069.91020320635 102007.16023416595 98700.1693157895 101147.3887338119 1.0223300202475103 0.9367614498839562 1.055189620048193 1.1854714341262775 1.0165441617363993 0.9721298843207936 0.9992340036497686 1.0085001848403294 0.9758054117989867 1.0 16.626099549553885 -6.5173979633868155 24.873253085647068 0.9924120282530975 1.0495765088764968 0.18862612551481261 0.05746184553475818 453.5489697341186 2058339.1871861778 0.0205685837561151 0.02117681617063618 3.038099803525694e-07 6.5173979633868155 0.057164480623399294 EPALPLEPDSGGNTS(ph)PGVTANGEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EPALPLEPDSGGNTSPGVTANGEAR 25 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;Q5VY93 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 EPALPLEPDSGGNT(0.279)S(0.72)PGVT(0.001)ANGEAR;EPALPLEPDSGGNT(0.146)S(0.854)PGVTANGEAR 157.01 6.678999999999999e-08 16430300.0 61159.0 60166.0 68072.0 68031.0 96828.0 89624.0 81696.0 86002.0 78309.0 67760.0 True False 71512.01075468874 66138.88285675838 69695.09464449766 64219.44362947781 77855.24848561396 84923.95966596507 73957.16345218007 83744.53862665102 79454.12097892717 80044.35161213498 0.8934048351245223 0.8262779512193776 0.8707059678890778 0.8022982551056349 0.9726513728647763 1.060961304021486 0.9239523084720438 1.046226709817649 0.9926262050810549 1.0 16.288511981058356 -6.379692529595381 5.147688869819904 1.0037919343914532 0.8488262723501239 0.7661590942834644 0.04116444359203401 0.1025584585028747 3.92225702561938 0.012222801995845996 0.013883073716692299 4.1716462180865573e-07 6.379692529595381 -0.15496566204132933 EPALPLEPDSGGNTS(ph)PGVTANGEAR ddPTM_PC-9_Lapatinib_30min_R1 3 EPALPLEPDSGGNTSPGVTANGEAR 25 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;Q5VY93 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 EPALPLEPDSGGNT(0.373)S(0.62)PGVT(0.007)ANGEAR;EPALPLEPDS(0.003)GGNT(0.253)S(0.744)PGVT(0.001)ANGEAR;EPALPLEPDSGGNT(0.09)S(0.908)PGVT(0.002)ANGEAR 136.48 1.9751e-09 16419800.0 92740.0 76446.0 90965.0 69093.0 87293.0 82435.0 78296.0 74965.0 95947.0 69078.0 True False 91417.51059356704 76268.99398382814 83486.20883505451 74174.32970749142 82158.59736464122 78909.44721537067 82349.78377472969 78448.1475731875 85140.4384932985 81018.04025935057 1.1283599344161652 0.9413828542344391 1.0304644319685217 0.915528559689281 1.0140778165164148 0.9739737836507772 1.0164376169938942 0.9682799944563399 1.050882472851127 1.0 16.305955567729676 -8.26319651453787 24.980406371138454 1.0254412310645982 0.9952460017662236 0.032795296137461016 0.056119225491107746 586.023639390853 8330844.78488407 0.04174470048496926 0.013099889026040916 5.455109661909636e-09 8.26319651453787 -0.030195229298374593 EPAPAEALPQQYPEPAPAALCGPPPRAPS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 EPAPAEALPQQYPEPAPAALCGPPPRAPSR 30 1 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 EPAPAEALPQQYPEPAPAALCGPPPRAPS(1)R 62.17100000000001 0.00028308 6893400.0 5898.2 1912.9 6002.3 9351.7 10238.0 6242.8 5041.5 9250.2 3872.4 7497.7 True False 7773.70490981866 2531.207516201681 5922.705580166853 7195.8100473247205 8816.630420743737 5852.436729119586 5490.183733320386 7820.794138449594 4077.0871583387175 7235.2078051222625 1.0744273169756315 0.34984586267303597 0.8185950894145423 0.9945547164837961 1.2185732128525577 0.8088830185328298 0.7588149340276773 1.080935661987864 0.563506573432803 1.0 12.820818738200565 -5.517642432611216 24.682793172351587 0.9213908349405597 0.6801575759580772 0.10637820800279463 0.23601457699733955 332.60285309281755 1567810.9727132097 0.061221526581867636 0.11016556086179881 3.0363901043940193e-06 5.517642432611216 -0.2412332589824825 EPCPVVPPREAS(ph)IR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EPCPVVPPREASIR 14 1 A0A384DVL8;Q8TD84-2;Q8TD84 A0A384DVL8 DSCAML1 Down syndrome cell adhesion molecule-like protein 1 1 EPCPVVPPREAS(1)IR 89.23100000000001 0.026088999999999998 9574800.0 1303.0 0.0 1116.1 884.02 941.53 0.0 935.97 1099.9 629.59 0.0 True False 1523.572164576916 0.0 1142.71205683282 834.4912254315095 757.0439553296574 0.0 847.3081457640163 1071.0287904403817 638.7965626827399 0.0 0.0 EPCPVVPPREAS(ph)IR ddPTM_PC-9_Lapatinib_30min_R1 2 EPCPVVPPREASIR 14 1 A0A384DVL8;Q8TD84-2;Q8TD84 A0A384DVL8 DSCAML1 Down syndrome cell adhesion molecule-like protein 1 1 EPCPVVPPREAS(1)IR;EPCPVVPPREAS(1)IR 98.94200000000001 0.011238 16940400.0 4170.799999999999 3308.4 2664.08 1880.2 1933.6100000000001 2574.8 2685.4 4023.4 4529.9 2046.0 True False 4111.323627168955 3300.7396030674886 2445.0496260461905 2018.4761801633317 1819.878861423527 2464.6818061519557 2824.436872236887 4210.341852143824 4019.6949600382754 2399.648373876368 1.7133025287899006 1.3755096950873291 1.0189199603842298 0.8411549800951484 0.7583939718983548 1.027101234073946 1.1770211431745394 1.7545661681017373 1.675118323083686 1.0 11.228607304483322 -7.630257595740316 6.614227226788714 1.5331302514233085 1.100260605072747 0.19407102687609734 0.3164982556237868 0.3085142121751375 16.95264834587917 0.16080700906770026 0.09178460670312852 2.3428387808361143e-08 7.630257595740316 -0.43286964635056147 EPDATPPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 EPDATPPSPR 10 0 A0A494C0S2;A0A090HNM7;A0A1W2PS85;R4GMW8;P28715 A0A494C0S2 ERCC5-201;BIVM-ERCC5;ERCC5 DNA repair protein complementing XP-G cells 1 EPDAT(0.157)PPS(0.843)PR 77.124 0.022197 10754000.0 20918.0 25330.0 22444.0 15125.0 30329.0 28242.0 26380.0 19135.0 26510.0 20967.0 True False 20619.70548410861 25271.349941270553 20598.740956345417 16237.342955520908 28545.1078491082 27034.15549531752 27745.82732166868 20024.08195575188 23524.164637324164 24591.118013228635 0.8385021564703309 1.0276616918220631 0.8376496320852291 0.6602929946814997 1.1607893481602805 1.0993463363794467 1.1282865344610598 0.8142810727426079 0.9566122461235593 1.0 14.585849706816683 -6.273890472725693 24.971990943426892 1.0259930191647475 0.8541164711355771 0.34941996083575044 0.12350161321405233 1017.2421108591008 2040183.4149053139 0.04141715431853198 0.047291433703219025 5.322424716948916e-07 6.273890472725693 -0.1718765480291704 EPDPDS(ph)DWEPEER ddPTM_PC-9_AZD4547_30min_R2 2 EPDPDSDWEPEER 13 0 Q9NPE2-3;Q9NPE2 Q9NPE2-3 NGRN Neugrin 1 EPDPDS(1)DWEPEER;EPDPDS(1)DWEPEER 142.1 2.9751e-05 0.0 16012.900000000001 14821.099999999999 18950.2 20716.8 22909.0 16803.1 16683.1 21845.9 17670.2 17130.1 True False 21104.66911098901 19611.73073259278 18698.907966159277 15940.861831369357 19728.480788124452 15752.399500715916 18167.863580552883 18470.118123841217 18604.210697571718 16530.38041299665 1.2767201107117854 1.1864052878767077 1.1311843707757427 0.9643372646667105 1.193468044607937 0.95293629711818 1.099059012959484 1.11734380349284 1.1254556902359347 1.0 14.012832305246144 -5.112742248031776 1.9441388909675068 1.0713373580003605 1.2782834924841113 0.461827421310822 0.07305382410253856 0.3860188194969777 2.3939054282377636 0.019540359825973838 0.11252763205440426 7.713611328634933e-06 5.112742248031776 0.20694613448375088 EPEAASS(ph)RGSPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EPEAASSRGSPVR 13 1 F8WC91;B9A018;Q53GS9-3;Q53GS9 F8WC91 USP39 U4/U6.U5 tri-snRNP-associated protein 2 1 EPEAAS(0.027)S(0.801)RGS(0.172)PVR 85.973 0.0036924999999999996 47897000.0 24445.0 11971.0 27637.0 23246.0 27772.0 28109.0 26572.0 27479.0 27671.0 22095.0 True False 28583.05568924231 13159.401766417146 28295.97089390616 21943.601984548855 22330.275962970103 26634.914556933574 24054.907795379597 26757.705366407172 28075.636026611126 26100.64859607624 1.0951090193804323 0.5041791094952109 1.0841098752680018 0.8407301413899606 0.855544868196381 1.020469451511548 0.9216210741596597 1.0251739633178965 1.0756681361102953 1.0 14.671798037483166 -6.975123695033158 0.7959525602296237 1.0379879291719156 0.8506983783715203 0.13492479730060203 0.15778080943486483 1.1711831857540336 1.5577687661539628 0.11049992162615103 0.0858113061755758 1.0589520732502914e-07 6.975123695033158 -0.18728955080039533 EPEAASSRGS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 1 EPEAASSRGSPVR 13 1 F8WC91;B9A018;Q53GS9-3;Q53GS9 F8WC91 USP39 U4/U6.U5 tri-snRNP-associated protein 2 1 EPEAAS(0.013)S(0.013)RGS(0.975)PVR 100.18 0.011191 12402000.0 16519.0 15155.0 24315.0 37403.0 29686.0 21862.0 16009.0 25513.0 17847.0 25802.0 True False 21771.69838345505 20053.557377822413 23992.567212861235 28780.316220589477 25564.611317659554 20494.96568398994 17433.769986457617 21570.552080416055 18790.355984627382 24898.67983351758 0.8744117571304677 0.8054064517439651 0.9636080054559129 1.155897277005289 1.0267456543316615 0.8231346328812364 0.7001885281881086 0.8663331640330048 0.7546727822626393 1.0 14.603781629950083 -6.810412557272413 9.231716802971192 0.8120819382508021 0.9667593920591145 0.2602135728873607 0.11319343006666811 0.4628232056250785 82.14355543730574 0.04269075833300583 0.03775105417281033 1.547346021919868e-07 6.810412557272413 0.15467745380831244 EPEAASSRGS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 2 EPEAASSRGSPVR 13 1 F8WC91;B9A018;Q53GS9-3;Q53GS9 F8WC91 USP39 U4/U6.U5 tri-snRNP-associated protein 2 1 EPEAAS(0.222)S(0.222)RGS(0.555)PVR;EPEAAS(0.158)S(0.032)RGS(0.81)PVR 114.21 0.0014879000000000001 29965000.0 55979.0 40784.0 45811.0 35080.0 36235.0 37843.0 27428.0 29638.0 42050.0 26248.0 True False 55180.729194708685 40689.567153761476 42044.59641557389 37659.90022344949 34103.72854075098 36224.54310634164 28848.087633765295 31015.089678838485 37313.886193869526 30784.931826738473 1.7924590350003982 1.3217364710361406 1.3657524613731888 1.2233225149045064 1.1078058815491656 1.1766972007675052 0.9370846684386379 1.0074763151464934 1.2120827943968446 1.0 14.909936753256414 -1.5228787453016353 0.4594187471368186 1.0441122444316262 18.069145097786045 0.8412527581684592 0.0931969371454614 33.81896741398301 0.3986748695615687 0.05640308420190577 543.2881298061998 0.029999999998528808 1.5228787453016353 17.025032853354418 EPEDEGEDDD ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EPEDEGEDDD 10 0 P39687 P39687 ANP32A Acidic leucine-rich nuclear phosphoprotein 32 family member A 0 ; 95.90899999999999 0.026423000000000002 3396400.0 37330.0 55044.0 45405.0 48670.0 50829.0 46903.0 53934.0 43874.0 45210.0 38137.0 False True 43649.23169889201 60508.404546877086 46487.6273994214 45943.17769026897 40869.42232902953 44443.32411198744 48824.98107165447 42722.35398834557 45871.11072108306 45050.93620767413 0.9688862290825523 1.3431109237763161 1.0318903737122014 1.0198051707179139 0.907182530916365 0.9865127753863816 1.0837728398491628 0.9483122346538071 1.0182054932139062 1.0 15.45926946667893 -5.500251237496778 24.442200886265226 0.9949557116068167 1.1638741335708465 0.3111893863734102 0.0944293986542597 575.2792487530112 621414.2851378045 0.02306809203482249 0.04741683542656716 3.1604488251303218e-06 5.500251237496778 0.16891842196402973 EPEPAAGPQAEESATVSAPAPMS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EPEPAAGPQAEESATVSAPAPMSPTR 26 0 Q9BWG6-2;Q9BWG6 Q9BWG6-2 SCNM1 Sodium channel modifier 1 1 EPEPAAGPQAEES(0.007)AT(0.078)VS(0.197)APAPMS(0.567)PT(0.151)R 71.907 0.002061 0.0 10267.0 17965.0 16269.0 13793.0 15004.0 9533.8 14826.0 14451.0 9946.6 9928.1 True False 12005.000317506678 19748.44647345118 16656.914660526076 13020.222927509341 12064.073907115207 9033.8307447043 13421.573949055311 14071.676562100143 10092.050207881543 11727.985939203643 1.0236199446127443 1.6838736485381687 1.420270688153393 1.110184049930183 1.0286569211161918 0.7702798069109655 1.1444056992079465 1.1998374345813414 0.8605100875970879 1.0 13.517667658473739 -5.862277559591518 3.7083330644782255 1.010577435713533 1.4079502788937652 0.4353483903813854 0.1896055577906641 0.20294568693010195 5.328213865189313 0.05430265488637519 0.0855070422245704 1.3731640990532849e-06 5.862277559591518 0.39737284318023214 EPFAHS(ph)LPPARGSPDLAALR ddPTM_PC-9_AZD4547_30min_R2 1 EPFAHSLPPARGSPDLAALR 20 1 A2A288 A2A288 ZC3H12D Probable ribonuclease ZC3H12D 1 EPFAHS(1)LPPARGSPDLAALR 67.685 0.026198000000000003 40074000.0 16487.0 14542.0 25138.0 39417.0 32614.0 21794.0 25527.0 34402.0 19614.0 30447.0 True False 21729.523049096388 19242.41711569076 24804.65369512259 30330.019636579284 28086.109058618484 20431.217734739592 27798.853547648392 29085.96137931537 20650.755997225388 29381.059797345544 0.7395758763970645 0.6549259028916729 0.8442395838071024 1.0322983529450314 0.955925662734465 0.6953873643654429 0.946148768607724 0.9899561683592899 0.7028594659165799 1.0 14.842598815498066 -5.401020749145925 4.808017065343816 0.9006820623935788 0.6998371103859629 0.3429204098534634 0.11209966501599676 0.24421111337906787 8.436818013528738 0.02970474268360806 0.06406683030568452 3.971725734315361e-06 5.401020749145925 -0.20084495200761598 EPFPPS(ph)SPLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EPFPPSSPLQK 11 0 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 EPFPPS(0.5)S(0.5)PLQK;EPFPPS(0.625)S(0.375)PLQK;EPFPPS(0.655)S(0.345)PLQK 129.74 0.00099926 10703600.0 51342.6 70055.0 70899.0 89286.0 171873.0 148641.0 205868.0 154814.0 160924.0 144405.0 True False 60033.888117426555 77009.59742263409 72589.50104595469 84283.59488911749 138195.71945065423 140846.00429247427 186366.69268475097 150750.29653899168 163277.2090617025 170584.4833906492 0.3519305327433866 0.4514455001530079 0.4255340204637497 0.4940871128126159 0.8101306561053231 0.8256671503347 1.0925184341530028 0.8837280715254975 0.9571633117872006 1.0 17.380126897450282 -6.362666811157199 1.4383414580385758 0.9687028243231747 0.39859234701543755 0.9373866918049448 0.06447913926594045 0.08965628641942212 0.3743442092409845 0.024496366819782404 0.031123161832313225 4.3384359366565104e-07 6.362666811157199 -0.5701104773077371 down EPFPPSS(ph)PLQK ddPTM_PC-9_AZD4547_30min_R2 5 EPFPPSSPLQK 11 0 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 EPFPPS(0.04)S(0.96)PLQK;EPFPPS(0.112)S(0.888)PLQK;EPFPPS(0.285)S(0.715)PLQK;EPFPPS(0.139)S(0.861)PLQK;EPFPPS(0.042)S(0.958)PLQK 187.78 0.00015341 51807800.0 414233.0 520510.0 501300.0 491195.0 498834.0 582945.0 529164.0 583153.0 520591.0 493208.0 True False 545950.4774183497 688754.6783721773 494652.4344563988 377957.5816371 429579.5096016092 546493.3569963181 576258.5708734997 493040.10337282356 548108.3774524097 475940.9380408319 1.147097116011297 1.447143171182908 1.0393147445827862 0.794127067936052 0.9025899544803493 1.1482377608572798 1.2107774826969422 1.0359270740659101 1.1516310820175475 1.0 18.860423027628954 -5.287673134877318 22.490794194993693 1.033552570481818 1.2971200233291278 0.3796273512130197 0.13384996080757822 202.45671194710786 173570.62122787954 0.03780424500430243 0.07876562615015031 5.156165695330425e-06 5.287673134877318 0.26356745284730976 EPFPPSS(ph)PLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EPFPPSSPLQK 11 0 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 EPFPPS(0.08)S(0.92)PLQK;EPFPPS(0.455)S(0.545)PLQK;EPFPPS(0.044)S(0.956)PLQK;EPFPPS(0.292)S(0.708)PLQK 174.21 0.0014156 26348000.0 108671.0 135537.0 157596.0 165459.0 341664.0 282380.0 433407.0 311772.0 325411.0 303632.0 True False 127066.85394991412 148992.21762717262 161353.68632615847 156188.86865531598 274717.39185554616 267571.4956984207 392351.5513650488 303588.31534974015 330169.520257871 358678.07805040997 0.3542643437831059 0.4153925950451666 0.4498565599637266 0.43545696883477947 0.7659163151223765 0.7459934466940441 1.0938821616801075 0.846408894014071 0.9205177022596507 1.0 18.45233004673411 -6.469185764424488 1.3006965477656462 0.9490246975487469 0.3891145551833346 0.9010232357066521 0.08049725618621292 0.12250333392272421 0.42792996706251646 0.03314757987709252 0.039006728019386136 3.394800328860469e-07 6.469185764424488 -0.5599101423654123 down EPFPPSS(ph)PLQK ddPTM_PC-9_Lapatinib_30min_R1 5 EPFPPSSPLQK 11 0 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 EPFPPS(0.225)S(0.775)PLQK;EPFPPS(0.232)S(0.768)PLQK;EPFPPS(0.226)S(0.774)PLQK;EPFPPS(0.224)S(0.776)PLQK;EPFPPS(0.145)S(0.855)PLQK 172.33 0.00015079 42358800.0 152251.0 209175.0 201807.0 196085.0 519325.0 619158.0 633557.0 635254.0 613021.0 518435.0 True False 150079.87282058623 208690.66813917347 185215.20745754772 210505.74502038473 488779.32453223376 592678.0556677931 666359.481441791 664770.2199487434 543976.1195826895 608045.7989787841 0.2468233035614194 0.34321537701546573 0.30460733018568265 0.3462004759738989 0.8038528106815983 0.9747260102169916 1.0959034378017989 1.0932897177568337 0.8946301750563856 1.0 19.213820468288418 -6.38317519306463 2.178435042014298 1.025843943487773 0.2955343326375237 0.9693568709003206 0.0590696655673122 0.049755528920617666 0.46423164088384455 0.021140425860132296 0.025001253952362096 4.1383270229852236e-07 6.38317519306463 -0.7303096108502494 down EPGDVAT(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EPGDVATPPR 10 0 H3BT22;Q9Y5N6 H3BT22 ORC6 Origin recognition complex subunit 6 1 EPGDVAT(1)PPR 77.124 0.0365 0.0 19026.0 24277.0 40984.0 20207.0 28842.0 22107.0 19287.0 18039.0 16886.0 18223.0 True False 22246.726019371006 26687.060118896443 41961.21399268556 19074.86730197791 23190.61714402938 20947.670002850686 17459.995734212185 17565.495363900398 17132.925804826555 21526.685646811366 1.0334487335567284 1.2397198787008559 1.9492649579755932 0.8861033052156531 1.0772962231398815 0.9731024248943568 0.8110861105457003 0.8159869871329812 0.7958924139984533 1.0 14.393838591809386 -5.88155140688939 20.535532287060125 0.9063582783052323 1.395449434487615 0.4942931760367232 0.2311674931796357 2.0502704012199797 352.95884570030705 0.06646395312350048 0.09858239484266317 1.3135560017923243e-06 5.88155140688939 0.48909115618238264 EPGEQASVPLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 EPGEQASVPLSPK 13 0 P42858 P42858 HTT Huntingtin 1 EPGEQAS(0.452)VPLS(0.548)PK;EPGEQASVPLS(1)PK 119.96 0.00021989999999999998 17184600.0 89303.0 99096.0 81318.0 66917.0 73205.0 75799.0 108699.0 86976.0 91635.0 86696.0 True False 117699.49638220755 131126.84407210088 80239.67018776272 51490.31950734399 63041.74936027983 71059.27654746837 118373.00042213482 73535.85770964883 96478.63902343975 83660.79942820848 1.4068655473846932 1.567363029857541 0.9591071414111753 0.6154653058452924 0.7535398871532133 0.8493736257976615 1.414915961013662 0.8789762733829942 1.1532120142627922 1.0 16.35226416339802 -5.268089524195314 23.505617480133797 0.9423585857942102 1.4871143181113227 0.5089249622295855 0.2096253017991459 171.74557886112459 607058.1001646746 0.058672866407770384 0.1271752642393556 5.393994208338614e-06 5.268089524195314 0.5447557323171125 EPGEQASVPLS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EPGEQASVPLSPK 13 0 P42858 P42858 HTT Huntingtin 1 EPGEQAS(0.027)VPLS(0.973)PK;EPGEQASVPLS(1)PK 128.74 0.00010126 11203200.0 51551.0 68012.0 41547.0 58128.0 54051.0 50388.0 59153.0 43682.0 39411.0 38049.0 True False 60277.5661213389 74763.78188435092 42537.63804787495 54871.2766135187 43460.09455835005 47745.56457699555 53549.59960936658 42535.393784904765 39987.311316713196 44946.98250428173 1.3410814867404448 1.6633771105152337 0.9463958574710268 1.2208000082829045 0.9669190708010257 1.0622640701730584 1.1913947639146933 0.946345926133145 0.8896550800246475 1.0 15.455936643849023 -5.2666950893691675 24.999999999132534 1.0378231411242866 1.5022293091762011 0.6988556141832499 0.12439381698203433 205.99322955678633 979858.8845293391 0.03157395229643038 0.06900411723649022 5.411341104917335e-06 5.2666950893691675 0.4644061680519145 EPGEQASVPLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 EPGEQASVPLSPK 13 0 P42858 P42858 HTT Huntingtin 1 EPGEQASVPLS(1)PK;EPGEQASVPLS(1)PK 161.24 0.00021948 20608100.0 87482.0 140732.0 91011.0 108493.0 108022.0 108542.0 108827.0 121432.0 92506.0 82453.0 True False 86234.4906377659 140406.14370054821 83528.42689261964 116471.93714203818 101668.35833942333 103899.91168376022 114461.5295653994 127074.17402931051 82087.00014863479 96704.89118828335 0.8917283249910112 1.451903228216027 0.8637456271988427 1.2044058548731378 1.0513259163021669 1.0744018260820773 1.1836167556669297 1.3140408149769645 0.8488402100449326 1.0 16.561301240447264 -8.281458874907422 24.94475856908175 0.9244200942275785 1.1311634862620763 0.18589234691204826 0.17155057529845383 1447.0016795161537 1802979.8380289897 0.15159496253298851 0.03934111362194148 5.230474933096268e-09 8.281458874907422 0.20674339203449776 EPGGRS(ph)PAFVQLAPLSSK ddPTM_PC-9_Lapatinib_30min_R1 2 EPGGRSPAFVQLAPLSSK 18 1 P51610;A6NEM2;P51610-2;P51610-4 P51610 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 EPGGRS(1)PAFVQLAPLSSK;EPGGRS(1)PAFVQLAPLSSK 83.25299999999999 0.0010869000000000002 15265600.0 86400.0 68559.0 85258.0 75694.0 68121.0 70167.0 70702.0 64950.0 75905.0 64896.0 True False 85167.92015618042 68400.25584775253 78248.41634539735 81260.78926778186 64114.25671103899 67166.1209772659 74362.60361245718 67967.81411163232 67355.77958491482 76113.18713151554 1.1189640503296656 0.8986649807419589 1.0280533412717607 1.0676308840854583 0.842354119270506 0.8824505123036032 0.9770002599413747 0.8929834194722542 0.8849423092549147 1.0 16.215858811741334 -6.255463491825904 24.998158687875815 0.9095813024140155 1.0190470065488713 0.4063633603618294 0.06765778798058356 517.9027909881316 2166474.325799428 0.01977480217769059 0.024863492759348467 5.553112963895779e-07 6.255463491825904 0.10946570413485579 EPGPIAPS(ph)TNSSPVLK ddPTM_PC-9_AZD4547_30min_R2 1 EPGPIAPSTNSSPVLK 16 0 Q14674-2;Q14674 Q14674-2 ESPL1 Separin 1 EPGPIAPS(0.756)T(0.027)NS(0.091)S(0.126)PVLK 179.66 5.2071000000000005e-06 23439000.0 112860.0 119210.0 132190.0 157960.0 140340.0 151140.0 127210.0 137000.0 120090.0 137580.0 True False 148747.13236616817 157742.30122139282 130437.07422858842 121544.7624576721 120856.2134447329 141689.19190733877 138531.44356157613 115829.7979468116 126437.71223140607 132763.36607609308 1.1203928972463233 1.1881462927882012 0.9824779085054882 0.9154992529189787 0.9103129652156031 1.0672310901346826 1.0434463034191004 0.8724530069569338 0.9523539208770778 1.0 17.01849758745108 -5.300880963590221 6.818665193234952 0.9652413678534975 1.1542401299797764 0.6164724745375953 0.05877016329521884 0.131316751462661 18.31753646647443 0.016447965002601133 0.03533952083461895 5.001716089586068e-06 5.300880963590221 0.18899876212627897 EPGPIAPS(ph)TNSSPVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EPGPIAPSTNSSPVLK 16 0 Q14674-2;Q14674 Q14674-2 ESPL1 Separin 1 EPGPIAPS(0.389)T(0.048)NS(0.174)S(0.389)PVLK 149.59 3.0656e-05 13564000.0 132320.0 160390.0 143710.0 137020.0 160440.0 137630.0 155910.0 130500.0 135650.0 100930.0 True False 154719.16256087323 176312.45921941777 147136.5914232103 129343.21362483373 129002.93372817658 130412.44051623208 141141.0761093497 127074.51327617915 137633.62462541272 119227.81003855944 1.2976767963014295 1.478786360014468 1.2340794599483533 1.0848409744589191 1.0819869432010516 1.0938089064460332 1.183793244744689 1.0658126928195863 1.154375179590237 1.0 16.863361259944675 -5.524480026393103 3.764039150646832 1.1018589941829204 1.3868007310741268 0.7783990318155664 0.06257328608320574 0.08930385524600314 2.7818370828382455 0.016108878805052632 0.032556361342998864 2.9889591088059845e-06 5.524480026393103 0.2849417368912064 EPGPIAPS(ph)TNSSPVLK ddPTM_PC-9_Lapatinib_30min_R1 2 EPGPIAPSTNSSPVLK 16 0 Q14674-2;Q14674 Q14674-2 ESPL1 Separin 1 EPGPIAPS(0.25)T(0.25)NS(0.25)S(0.25)PVLK;EPGPIAPS(0.326)T(0.128)NS(0.273)S(0.273)PVLK 173.19 1.4808e-05 16072000.0 88730.8 108162.9 113499.8 102922.4 96923.0 101765.0 106735.0 92911.3 108460.0 73945.0 True False 87465.48252076402 107912.45545055866 104168.28456589802 110491.65663506165 91222.17969794974 97412.74817580164 112261.21604163406 97228.29818737641 96244.09266556684 86726.29472448085 1.0085232258409227 1.2442876268769896 1.2011153583446441 1.2740271792549254 1.0518399291443477 1.1232204544800442 1.2944311341591916 1.1210936486593734 1.1097452389880476 1.0 16.404181853010314 -8.568807216460504 1.8382396055898023 1.0017915031369384 1.172457613994484 0.24833660418608694 0.08779951923483707 0.5517126438154295 4.1884724883053 0.08308805576964456 0.02349792415208583 2.6989372261701807e-09 8.568807216460504 0.17066611085754557 EPGPIAPSTNS(ph)SPVLK ddPTM_PC-9_AZD4547_30min_R2 1 EPGPIAPSTNSSPVLK 16 0 Q14674-2;Q14674 Q14674-2 ESPL1 Separin 1 EPGPIAPS(0.134)T(0.057)NS(0.668)S(0.142)PVLK 173.51 1.4219e-05 17951000.0 181220.0 170200.0 206980.0 241800.0 218390.0 215440.0 207740.0 254110.0 213800.0 219160.0 True False 238844.19038983752 225213.82155759662 204235.30996167051 186056.74577275992 188070.31818579996 201968.5027426036 226228.45755429493 214843.13836689197 225101.03151864946 211487.2751071128 1.1293548998107292 1.0649048338418077 0.9657096856452978 0.8797538560110864 0.8892748657835193 0.9549912761432658 1.0697024558083512 1.0158679204603658 1.0643715155185656 1.0 17.69021133545511 -9.953598108802431 14.084975828995958 1.000002885314132 0.9982940829636088 0.0 0.07762860527595515 0.0 0.0 0.083965245675749 0.020364563341297045 1.1127609873971804e-10 9.953598108802431 -0.0017088023505232863 EPGPIAPSTNS(ph)SPVLK ddPTM_PC-9_Lapatinib_30min_R1 1 EPGPIAPSTNSSPVLK 16 0 Q14674-2;Q14674 Q14674-2 ESPL1 Separin 1 EPGPIAPS(0.109)T(0.109)NS(0.528)S(0.254)PVLK 166.3 3.0432e-05 16884000.0 149710.0 159890.0 188010.0 165780.0 179060.0 207160.0 173940.0 146260.0 187100.0 137170.0 True False 147575.10794654876 159519.78452861268 172552.54353958715 177972.0142258684 168528.04284550474 198300.24971354657 182945.76210504374 153055.77354838123 166026.82774965494 160879.65173246388 0.9173012643759322 0.9915473014193703 1.0725566700413722 1.1062431594632514 1.0475410720416016 1.2325999439836652 1.1371591132561305 0.9513681307745903 1.0319939530062545 1.0 17.295622338092322 -5.010118410454136 2.177005456328114 1.0797824435955197 0.9084440349316253 0.3139901894322207 0.07323500764267143 0.5216032819672338 3.9822945580056857 0.021343003658870124 0.1453967412462087 9.769708134039844e-06 5.010118410454136 -0.17133840866389438 EPGPIAPSTNSS(ph)PVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EPGPIAPSTNSSPVLK 16 0 Q14674-2;Q14674 Q14674-2 ESPL1 Separin 1 EPGPIAPS(0.02)T(0.02)NS(0.22)S(0.74)PVLK 171.15 2.5251e-05 5680600.0 39547.0 39618.0 37290.0 47764.0 52583.0 42316.0 51506.0 41930.0 41300.0 33299.0 True False 46241.526011146074 43551.01321375949 38179.13502311253 45087.93793297735 42279.73862022386 40096.87446693943 46626.97880885222 40829.38192850733 41903.93436807628 39335.84510526105 1.175556947801826 1.107158447904674 0.9705939943821416 1.14623031009818 1.074839971204002 1.0193469686399745 1.1853559694492493 1.0379688505293236 1.0652862358986603 1.0 15.263556958858857 -14.522878737196349 0.14321735412109043 0.7067038880667754 1.1136184703957315 0.16572287671025643 0.06418591500444572 281.48149559165853 2.436973196908453 23.556193366404006 0.37029856034674963 3.0000000558422165e-15 14.522878737196349 0.40691458232895605 EPGS(ph)PPSVQR ddPTM_PC-9_Lapatinib_30min_R1 1 EPGSPPSVQR 10 0 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 EPGS(0.97)PPS(0.03)VQR 87.641 0.010498 7472300.0 40768.0 49174.0 43894.0 30262.0 47449.0 44548.0 40771.0 39450.0 45965.0 47195.0 True False 40186.64084406442 49060.14062424156 40285.20475573987 32487.568431072636 44658.14310832325 42642.78588646007 42881.9228859649 41282.99101930555 40787.93766709187 55352.592866615414 0.7260118950688221 0.8863205512786557 0.727792550799132 0.5869204448897051 0.8067940596014561 0.7703846139460441 0.7747048632265265 0.7458185584690901 0.7368749240957805 1.0 15.75636327791479 -10.910180183466384 3.1748523788581258 1.0028034708114355 0.7524589121287512 0.523381032465857 0.07119359047660918 32071020.330200735 40793330.95346086 819822.3659913618 0.018488996894841743 1.2297584532228918e-11 10.910180183466384 -0.25034455868268435 EPGSPPS(ph)VQR ddPTM_PC-9_Lapatinib_30min_R1 1 EPGSPPSVQR 10 0 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 EPGS(0.228)PPS(0.772)VQR 81.625 0.016028999999999998 7219400.0 35414.0 47566.0 36865.0 36579.0 46808.0 48231.0 47980.0 42753.0 48674.0 46120.0 True False 34908.98986586778 47455.863849446345 33834.10200301524 39269.14168396688 44054.84546806872 46168.27256195239 50464.16963205695 44739.46045749987 43191.82156005722 54091.7805489629 0.6453658857516955 0.877321163545174 0.6254943294460279 0.7259724358384018 0.8144462064470418 0.8535173383719862 0.9329360046925743 0.8271027502413701 0.7984913996491716 1.0 15.723121767277128 -6.4826429694327645 2.470846593208397 0.8750966609764206 0.7231728410606116 0.4701484201135978 0.08180195205568595 0.2870005197108125 3.4888328899854075 0.027931086281755526 0.030715332877535882 3.2912208874144e-07 6.4826429694327645 -0.15192381991580894 EPGT(ph)Y(ph)T(ph)LR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EPGTYTLR 8 0 P48553 P48553 TRAPPC10 Trafficking protein particle complex subunit 10 3 EPGT(1)Y(1)T(1)LR 46.129 0.045749 0.0 8705.8 6895.5 8141.4 8338.7 8840.3 6946.3 6846.9 7518.0 6512.3 5154.4 True False 10179.519992612217 7580.039669228091 8335.521852431435 7871.50967343016 7108.106675624537 6582.023799737719 6198.312064736733 7320.6604659794375 6607.530067438819 6088.851917792047 1.6718291280605715 1.2449045848986227 1.3689808793139577 1.2927740368309932 1.1673968708048486 1.0809958738698489 1.01797714058784 1.202305551985582 1.0851848848764343 1.0 12.571954511372866 -1.522878745280362 0.3507296997892225 1.056368302288601 7.4232361805626415 0.7906605661182262 0.08700340230074591 28.87081859056281 0.40618135902178953 0.07444006740628757 121.64152247524119 0.02999999999999831 1.522878745280362 6.36686787827404 EPGVHPPIPPKPS(ph)SPVSSPNQLR ddPTM_PC-9_AZD4547_30min_R2 2 EPGVHPPIPPKPSSPVSSPNQLR 23 1 O95171-2;O95171;O95171-3;F2Z2X8 O95171-2 SCEL Sciellin 1 EPGVHPPIPPKPS(0.393)S(0.393)PVS(0.107)S(0.107)PNQLR;EPGVHPPIPPKPS(0.357)S(0.357)PVS(0.143)S(0.143)PNQLR 85.855 1.3637e-05 25085000.0 81851.0 90091.0 120104.0 156330.0 123361.0 122015.0 104526.0 138826.0 109564.0 131832.0 True False 107877.91539343665 119211.15392447366 118511.34248544041 120290.53377442312 106234.45451585928 114385.3827615056 113828.61150630677 117373.63160411696 115355.3293606608 127216.60180653763 0.8479861422292199 0.9370723021336625 0.9315713578457663 0.945556885392622 0.8350675384130558 0.8991388005745912 0.8947622392823351 0.9226282571406114 0.906763171807445 1.0 16.956927429501413 -9.42385942192261 0.9602115808247437 1.000897002730284 0.9020574986490748 0.4230387054848761 0.034392276420047274 5.84963755068649 5.353284350246467 0.050156871621561745 0.010913310887041472 3.768257550983173e-10 9.42385942192261 -0.09883950408120912 EPHLNYS(ph)PTCLEPPVLSIHPGAID ddPTM_PC-9_AZD4547_30min_R2 1 EPHLNYSPTCLEPPVLSIHPGAID 24 0 O75054;O75054-2 O75054 IGSF3 Immunoglobulin superfamily member 3 1 EPHLNY(0.045)S(0.634)PT(0.321)CLEPPVLSIHPGAID 63.125 0.0033218 1480600.0 1676.9 1440.3 7189.7 11866.0 8174.0 4552.8 4067.3 9236.2 3595.8 6285.8 True False 2210.119318313199 1905.8488083983918 7094.359880333474 9130.477027872494 7039.1811935103815 4268.112696279818 4429.281820595855 7808.957516761599 3785.8666470288063 6065.736055248616 0.36436127424318215 0.31419909983542416 1.169579390813552 1.505254588183406 1.1604826074519767 0.7036429968934547 0.730213411901305 1.287388281592733 0.6241396942672665 1.0 12.566467006483606 -5.255782605345092 24.84705405492687 1.0331816047291418 0.33928008754238365 0.5187044864470653 0.26312425617452834 342.085430877477 1502577.7500115314 0.07188173019892585 0.1792590042177743 5.549034112779306e-06 5.255782605345092 -0.6939015171867582 EPHS(ph)PADQPEQQAESTLTSAETR ddPTM_PC-9_AZD4547_30min_R2 3 EPHSPADQPEQQAESTLTSAETR 23 0 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2;H3BS99 H3BSS6 ZNF106 Zinc finger protein 106 1 EPHS(1)PADQPEQQAESTLTSAETR;EPHS(1)PADQPEQQAESTLTSAETR;EPHS(1)PADQPEQQAESTLTSAETR 175.76 2.0724e-14 18518800.0 23051.600000000002 25344.1 31109.4 22581.5 28321.6 32395.2 30806.699999999997 41021.0 25084.9 24620.299999999996 True False 30381.52929693397 33536.0846941121 30696.86902947914 17375.684055697173 24389.63470640121 30369.523022870322 33548.436619514236 34682.14701880404 26410.836602161664 23758.350790836095 1.2787726540620203 1.4115493532929653 1.292045449607526 0.7313505978874257 1.0265710326917392 1.278267304420147 1.4120692515599316 1.459787647894373 1.1116443575851513 1.0 14.536147073076126 -6.910152019969868 10.709983789097308 1.2928660617509171 1.1476656816426154 0.04037042661212531 0.2136206865040748 1.0843719905597102 121.11589344820126 0.08154433546161634 0.07192282119197584 1.2298382042268254e-07 6.910152019969868 -0.14520038010830172 EPHS(ph)PADQPEQQAESTLTSAETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EPHSPADQPEQQAESTLTSAETR 23 0 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2;H3BS99 H3BSS6 ZNF106 Zinc finger protein 106 1 EPHS(1)PADQPEQQAESTLTSAETR 59.263000000000005 0.0034828000000000003 3932200.0 6978.3 7826.4 7837.0 9842.7 11941.0 8959.0 7691.2 7374.9 8239.7 6468.1 True False 8159.5883622924775 8603.353269124314 8023.863801988011 9291.245429463952 9601.246769185735 8489.174268581875 6962.633856534079 7181.316689352454 8360.190024519086 7640.715328548575 1.0679089602782608 1.12598793426827 1.0501456286439372 1.216017745713988 1.256590038541533 1.111044438059764 0.9112541898425492 0.9398749175382002 1.0941632641753167 1.0 12.899491995258169 -7.118347273766371 5.929025333411538 0.9823636739228193 1.1450706807106519 0.5147132643860473 0.0725423430323011 0.1998682629777309 8.962696591783756 0.029762820757594653 0.023016555632355263 7.614698743430808e-08 7.118347273766371 0.16270700678783256 EPHS(ph)PADQPEQQAESTLTSAETR ddPTM_PC-9_Lapatinib_30min_R1 4 EPHSPADQPEQQAESTLTSAETR 23 0 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2;H3BS99 H3BSS6 ZNF106 Zinc finger protein 106 1 EPHS(1)PADQPEQQAESTLTSAETR;EPHS(1)PADQPEQQAESTLTSAETR;EPHS(1)PADQPEQQAESTLTSAETR;EPHS(1)PADQPEQQAESTLTSAETR 123.84 1.2103e-08 25290800.0 39692.4 58288.0 51994.7 38316.9 58282.0 54713.2 59281.8 53364.2 49303.3 43475.2 True False 39126.379097305326 58153.03771720405 47719.896471346154 41134.85264743133 54853.96734682065 52373.243978698585 62351.121535924845 55843.69554758999 43750.2431672344 50989.83039293737 0.7673369139648039 1.140483058466083 0.9358708609855635 0.806726602744867 1.0757825025913108 1.0271311666483367 1.2228148447530653 1.0951928083942974 0.8580189977116353 1.0 15.637921918698995 -6.303390791336737 24.824132360963706 1.0590980214594774 0.9305432091807565 0.20371468411182136 0.12625435467645738 766.0251149975157 453282.1251195321 0.03946321944742318 0.044747400305680855 4.97289407512315e-07 6.303390791336737 -0.1285548122787209 EPHSFQSR ddPTM_PC-9_AZD4547_30min_R2 1 EPHSFQSR 8 0 H3BPH3;F8VR84;F8VQQ3;Q9HB07 H3BPH3 C12orf10 UPF0160 protein MYG1, mitochondrial 0 78.264 0.018778 1574500.0 4718.0 5084.5 7289.3 10487.0 8073.0 8403.1 4327.7 11106.0 6300.5 5886.1 False True 6218.225859503654 6727.965192183312 7192.63911925599 8069.384172534872 6952.203300123475 7877.652828612935 4712.856916134208 9389.822890491147 6633.53156727432 5680.029430589406 1.094752401460427 1.184494776726036 1.266303142818333 1.4206588664977264 1.2239731123016484 1.386903523102958 0.8297240311385436 1.6531292672398676 1.1678692246821636 1.0 12.471682689613063 -9.829367361867117 15.28414795426152 1.0000272397697099 1.2543709340508302 0.11444370323289843 0.2057813084385182 0.0 0.0 0.18869989548393903 0.04576644709548787 1.4812645800773026e-10 9.829367361867117 0.25434369428112036 EPLIPAS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 EPLIPASPK 9 0 Q9Y613 Q9Y613 FHOD1 FH1/FH2 domain-containing protein 1 1 EPLIPAS(1)PK;EPLIPAS(1)PK;EPLIPAS(1)PK 101.93 0.0033408 49941500.0 219062.0 236811.0 227825.0 259881.0 269580.0 256089.0 266840.0 272793.0 267616.0 253300.0 True False 288719.15922734025 313355.524658496 224803.89164178935 199969.45057142506 232153.47028951946 240075.71434668856 290588.24306242383 230639.11000952197 281761.63541110756 244432.0440985197 1.1811837531046887 1.2819739973708044 0.9196989391095584 0.8180983443022972 0.9497669225232545 0.9821777469157223 1.1888303930613149 0.9435714980011443 1.1527197117311754 1.0 17.89907390374899 -5.258417083918217 24.992238015467308 0.990965554482974 1.2315788913433978 0.4510726373090004 0.10462247785513958 237.72753076964108 1965813.1790962224 0.028501825228084064 0.06892336307842616 5.5154749451351916e-06 5.258417083918217 0.24061333686042385 EPLIPAS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EPLIPASPK 9 0 Q9Y613 Q9Y613 FHOD1 FH1/FH2 domain-containing protein 1 1 EPLIPAS(1)PK;EPLIPAS(1)PK;EPLIPAS(1)PK;EPLIPAS(1)PK 103.91 0.0027384 49260400.0 279307.0 316722.0 293982.0 436767.0 520421.0 483928.0 674290.0 671977.0 553207.0 516171.0 True False 326588.1585352906 348164.06701722235 300991.645812944 412296.3610077186 418448.2409234079 458549.96377344406 610416.3697631516 654338.3157684854 561296.6058101786 609748.7162926126 0.5356110637198358 0.5709959819745511 0.4936322746901872 0.676174217330966 0.6862634225253516 0.752031044134893 1.0010949649465415 1.0731278283732781 0.9205375768939178 1.0 19.21785529014752 -6.886135746664421 1.1453146767456213 1.0202451561564652 0.5522504933071208 0.9137029098926053 0.05933021210960753 0.1278179794969623 0.35092964994773074 0.03366458122680592 0.026933097103453915 1.2997632498148432e-07 6.886135746664421 -0.4679946628493443 EPLIPAS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 EPLIPASPK 9 0 Q9Y613 Q9Y613 FHOD1 FH1/FH2 domain-containing protein 1 1 EPLIPAS(1)PK;EPLIPAS(1)PK;EPLIPAS(1)PK 93.345 0.0063279 40981200.0 486733.0 458155.0 336704.0 412780.0 509539.0 524144.0 598904.0 562097.0 532840.0 498718.0 True False 479792.0981641006 457094.17024645937 309021.49683502666 443137.2181937145 479568.91781221714 501727.5829593408 629912.3186602218 588214.0786559851 472825.94814605115 584920.7418000365 0.820268566109636 0.7814634318485555 0.5283134530056895 0.7576021613287348 0.8198870095397721 0.8577702021906817 1.0769190997086684 1.005630398480679 0.8083590038044735 1.0 19.157881623647846 -6.706283755335791 1.847246277911506 0.9703794871344718 0.7150686284974914 0.5555410387528655 0.09850673020065935 0.2630805043813981 1.851353539720604 0.041403423870623283 0.0394401569897147 1.9666009502025093e-07 6.706283755335791 -0.25531085863698033 EPLLS(ph)SSENGNGGR ddPTM_PC-9_AZD4547_30min_R2 1 EPLLSSSENGNGGR 14 0 M0QZR4;Q92888-2;Q92888;Q92888-3;Q92888-4;M0R2C7;M0QYC1 M0QZR4 ARHGEF1 Rho guanine nucleotide exchange factor 1 1 EPLLS(0.77)S(0.056)S(0.174)ENGNGGR 103.66 0.0011591 6659400.0 3033.4 7955.1 10403.0 10853.0 8564.9 9316.8 4161.5 9285.7 11618.0 6560.0 True False 3997.958101360404 10526.430504540755 10265.049422800545 8351.008527178503 7375.811475935537 8734.21902317252 4531.865438106275 7850.808429158442 12232.103761382916 6330.336396708597 0.6315553946610337 1.6628548381747739 1.6215646024969175 1.3192045420399043 1.165153163072112 1.3797401079212475 0.7158964633321191 1.2401881886151265 1.9322991694000482 1.0 12.62806645176721 -6.012681446658601 23.570793137370703 1.232727869832144 1.3626289313847184 0.0011747246187929772 0.39096845858501544 1535.3592002233627 2853764.7427963717 0.11425845503653183 0.15539836161993445 9.712220937335844e-07 6.012681446658601 0.12990106155257442 EPLLS(ph)SSENGNGGR ddPTM_PC-9_Lapatinib_30min_R1 2 EPLLSSSENGNGGR 14 0 M0QZR4;Q92888-2;Q92888;Q92888-3;Q92888-4;M0R2C7;M0QYC1 M0QZR4 ARHGEF1 Rho guanine nucleotide exchange factor 1 1 EPLLS(0.889)S(0.055)S(0.055)ENGNGGR;EPLLS(0.871)S(0.064)S(0.064)ENGNGGR 105.17 0.00099663 8561800.0 0.0 2726.5 4774.67 1373.7 7933.3 18650.9 18967.5 13988.4 18439.2 18688.2 True False 0.0 2720.1869567656595 4382.115063359196 1474.726480528864 7466.6788914679055 17853.244484371407 19949.54434130972 14638.352131164867 16362.38312261591 21918.430469538765 0.0 0.12410500653986385 0.19992832376612274 0.06728248551274561 0.3406575530964571 0.8145311549192827 0.910172120628559 0.6678558554413183 0.7465125363495166 1.0 14.419856873336771 -6.631437766010971 3.010389088063363 0.8166866399376232 0.110746935286891 0.9267311672964829 0.09753676354407997 0.06686385856138623 1.217004499653179 0.03522667861652675 0.03519118217607226 2.3364808937357738e-07 6.631437766010971 -0.7059397046507323 down EPLPGLTREPVAES(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 EPLPGLTREPVAESPK 16 1 A0A0G2JNN3;C9JMY0;A0A087WUE4;Q96PV6-1;Q96PV6 A0A0G2JNN3 LENG8 Leukocyte receptor cluster member 8 1 EPLPGLTREPVAES(1)PK 69.081 0.010435 9650100.0 31796.0 19418.0 23012.0 44635.0 47595.0 28898.0 28644.0 26548.0 22563.0 34902.0 True False 41906.466602114895 25694.488760313787 22706.845844226304 34345.090353875676 40987.255799501676 27091.00349171812 31193.260509219304 22445.61661234999 23755.63411672255 33680.091603342 1.2442503748403289 0.7628984226920624 0.6741919265437257 1.0197445647822314 1.2169579668077448 0.8043625240327417 0.9261631730872153 0.6664357352912532 0.7053316361635231 1.0 15.03960844181087 -7.437602740741361 2.3028379827496335 0.7714785093826335 0.9501645108703145 0.1135051947242316 0.1918829843989059 0.6662198805007642 6.929183638404642 0.1057107636447487 0.060310701849013756 3.650877484850428e-08 7.437602740741361 0.178686001487681 EPLPGLTREPVAES(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 EPLPGLTREPVAESPK 16 1 A0A0G2JNN3;C9JMY0;A0A087WUE4;Q96PV6-1;Q96PV6 A0A0G2JNN3 LENG8 Leukocyte receptor cluster member 8 1 EPLPGLT(0.001)REPVAES(0.999)PK;EPLPGLTREPVAES(1)PK 94.18799999999999 0.0012429000000000001 25950000.0 204407.0 93578.0 75829.0 111697.0 71138.0 70670.0 45497.0 48723.0 79911.0 53102.0 True False 201492.11869634682 93361.325890415 69594.63232840474 119911.56999026894 66953.80270268922 67647.60883981618 47852.61204146926 50986.84845205635 70910.58167986471 62280.60994603269 3.2352303368728004 1.4990432170030823 1.1174365888309346 1.9253435394125804 1.075034473180432 1.0861744754657043 0.7683388470815306 0.818663280533659 1.1385659475928391 1.0 15.926495453089835 -2.5261628279934842 0.9855371836832414 1.0633020960868882 199.99999999999315 0.8178108981220391 0.2985349513689972 69.09252977902513 0.9514092818640841 0.10213850770695579 30048.663857274583 0.0029773999175493606 2.5261628279934842 198.93669790390626 up EPLPPFENQDIHS(ph)ASA ddPTM_PC-9_AZD4547_30min_R2 1 EPLPPFENQDIHSASA 16 0 Q14693;Q14693-2;Q14693-4;Q14693-3;Q14693-5;Q14693-7 Q14693 LPIN1 Phosphatidate phosphatase LPIN1 1 EPLPPFENQDIHS(0.689)AS(0.311)A 71.781 0.017416 1489800.0 3039.4 2119.1 2252.1 3730.8 4006.9 2992.7 3464.7 3625.9 3559.3 4741.4 True False 4005.8659765526522 2804.057633740908 2222.235682504001 2870.7217002854104 3450.6110991285486 2805.5659959050727 3773.0515879867394 3065.6004698930174 3747.437331545036 4575.405029169839 0.8755216097840144 0.6128545158000309 0.48569157666620905 0.627424606561285 0.7541651672649028 0.613184183262157 0.8246377236402439 0.670017288163282 0.8190394746812112 1.0 12.159683745591108 -8.798125453828632 0.5375135971332481 1.010850612087557 0.648465822427131 0.4668116178730314 0.10649112866076342 1.2118126460465137 0.7359431255444969 0.13689779974007993 0.053652791790232884 1.5917488551408014e-09 8.798125453828632 -0.3623847896604261 EPLPPFENQDIHS(ph)ASA ddPTM_PC-9_Lapatinib_30min_R1 2 EPLPPFENQDIHSASA 16 0 Q14693;Q14693-2;Q14693-4;Q14693-3;Q14693-5;Q14693-7 Q14693 LPIN1 Phosphatidate phosphatase LPIN1 1 EPLPPFENQDIHS(0.599)AS(0.401)A;EPLPPFENQDIHS(0.745)AS(0.255)A 117.13 0.001575 1177300.0 3053.8199999999997 4338.7 4662.5 4953.7 5910.0 5354.2 5724.9 7233.2 6598.6 3536.2 True False 3010.2719667979973 4328.654006718932 4279.167247770473 5318.011623058772 5562.385419507057 5125.213347249805 6021.307309849163 7569.280878094822 5855.396181661537 4147.427458309683 0.7258166651635318 1.0436961345872724 1.0317642178880886 1.2822434331922394 1.341165210343197 1.2357572010044575 1.4518173905091507 1.8250544353534617 1.4118140077241883 1.0 12.018001032220049 -5.1908539513591725 0.6363238681189038 1.4562710482168248 0.5441443767320177 0.511803173497984 0.20157962770574106 1.7192096320768042 0.7467583065770241 0.10397836027749478 1.0615771992287195 6.4438592925475445e-06 5.1908539513591725 -0.9121266714848072 EPLPPFENQDIHSAS(ph)A ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EPLPPFENQDIHSASA 16 0 Q14693;Q14693-2;Q14693-4;Q14693-3;Q14693-5;Q14693-7 Q14693 LPIN1 Phosphatidate phosphatase LPIN1 1 EPLPPFENQDIHS(0.035)AS(0.965)A 203.92 5.091600000000001e-51 0.0 4864.8 4785.5 3869.7 3389.8 4314.3 4492.8 6018.3 4959.8 5744.8 3510.0 True False 5688.314555820246 5260.572813732291 3961.968323918975 3199.88049587988 3468.943885461687 4257.189658877625 5448.203055281232 4829.610505342487 5828.806831906169 4146.335214855287 1.3718896956137148 1.2687282964688837 0.9555349769416204 0.7717370473124086 0.83662890376864 1.02673552384891 1.3139803640963899 1.164790171339547 1.4057731779676195 1.0 12.01762104203072 -7.245697707034958 22.60318973395174 1.2348684144950712 1.0239268792090144 0.17030357175956545 0.19491350005579794 404.82059501471275 581274.8847693097 0.08196569624570031 0.06318223904045524 5.6793978534253556e-08 7.245697707034958 -0.21094153528605686 EPPAAAPSAGGAAPCS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 EPPAAAPSAGGAAPCSPR 18 0 A6NEL2 A6NEL2 SOWAHB Ankyrin repeat domain-containing protein SOWAHB 1 EPPAAAPS(0.033)AGGAAPCS(0.967)PR 100.07 0.00061017 6738500.0 1819.9 4647.3 5183.6 6579.0 5945.8 5917.9 4569.8 6173.0 2062.9 4657.1 True False 2398.5903437284223 6149.448842095285 5114.86207709593 5062.313194536751 5120.328301978718 5547.852777480749 4976.50334712437 5219.104691428228 2171.9406825061824 4494.056346510916 0.5337250267435195 1.3683515220875184 1.138139285028545 1.1264463113523302 1.1393556082032716 1.2344866974772082 1.1073522366910273 1.1613349475424852 0.48329182258527487 1.0 12.133802497814143 -8.238760967898436 24.878872933025495 0.741645865879033 1.1180569070033097 0.2695920775459828 0.23538386913620976 754.4053882964258 827607.5109208348 0.14763507360405095 0.05571104455874795 5.77083998273849e-09 8.238760967898436 0.3764110411242767 EPPAAAPSAGGAAPCS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EPPAAAPSAGGAAPCSPR 18 0 A6NEL2 A6NEL2 SOWAHB Ankyrin repeat domain-containing protein SOWAHB 1 EPPAAAPS(0.001)AGGAAPCS(0.999)PR;EPPAAAPSAGGAAPCS(1)PR;EPPAAAPSAGGAAPCS(1)PR 152.86 2.9688e-05 12096400.0 16187.6 12408.8 19230.1 17684.300000000003 20951.0 20082.399999999998 19348.0 17481.9 14889.0 14823.7 True False 18927.840960326394 13640.663657097748 19688.618514560356 16693.506004274175 16845.801948011915 19029.243590955295 17515.217372610423 17023.01864860415 15106.723457779366 17511.119465655374 1.080904107669966 0.7789715377050127 1.1243495056484378 0.9533088982126593 0.962005997449315 1.0866948642705239 1.0002340174175093 0.9721262356750784 0.862693186886666 1.0 14.095983696097864 -8.015143356175644 20.714492069497904 0.9267008730145915 0.9941821203051834 0.06996381638811744 0.0956821553337143 191.90001078123558 262485.57079158997 0.05720781787492877 0.023389579910315567 9.657320480794246e-09 8.015143356175644 0.0674812472905919 EPPAAAPSAGGAAPCS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 EPPAAAPSAGGAAPCSPR 18 0 A6NEL2 A6NEL2 SOWAHB Ankyrin repeat domain-containing protein SOWAHB 1 EPPAAAPS(0.004)AGGAAPCS(0.996)PR;EPPAAAPS(0.024)AGGAAPCS(0.976)PR;EPPAAAPS(0.003)AGGAAPCS(0.997)PR;EPPAAAPSAGGAAPCS(1)PR 188.9 7.3779e-11 12157200.0 20739.3 20724.0 23522.5 20387.199999999997 19805.7 20003.2 20871.9 20567.5 24965.7 18635.0 True False 20443.553778878188 20676.014851278764 21588.570849475804 21886.542697705518 18640.76766550438 19147.709765736683 21952.54485500896 21523.141135350244 22153.799965524096 21856.034920423303 0.9353734038819078 0.9460094169211877 0.9877624614015615 1.0013958514155605 0.8528888123291555 0.8760834174841186 1.0044157110352836 0.9847687933202383 1.0136239279533064 1.0 14.415744073354205 -7.30647962476965 24.853651340907028 0.9994328778527053 0.9357543686164057 0.3767766036843223 0.042412090644575726 549.563667714418 303252.5054441861 0.019863234787837143 0.013391872916109163 4.9376508304161254e-08 7.30647962476965 -0.06367850923629959 EPPADVWT(ph)PPAR ddPTM_PC-9_AZD4547_30min_R2 2 EPPADVWTPPAR 12 0 A0A3B3IUA7;Q14258 A0A3B3IUA7 TRIM25 E3 ubiquitin/ISG15 ligase TRIM25 1 EPPADVWT(1)PPAR;EPPADVWT(1)PPAR 126.09 0.00066977 22755000.0 16195.2 22427.2 23141.8 29835.8 29005.4 23933.2 24788.0 26499.2 15828.1 23781.2 True False 21344.93671891343 29676.353812200512 22834.9246114165 22957.617268514907 24978.500879648385 22436.65322056848 26994.08397928109 22404.357531037567 16664.74105229342 22948.62742643391 0.9301182298304589 1.293164652541141 0.9950453326508565 1.0003917376806004 1.0884529351361694 0.9776904214639128 1.1762831596711238 0.9762831177097148 0.7261759382218105 1.0 14.486120247162624 -8.004466607968668 24.29630547229968 0.8591351178078305 1.0675268289003155 0.3234832289885844 0.1172227445106175 128.18847763325422 697280.2589362749 0.06243605313226306 0.028744425962651032 9.89767962216255e-09 8.004466607968668 0.208391711092485 EPPADVWT(ph)PPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EPPADVWTPPAR 12 0 A0A3B3IUA7;Q14258 A0A3B3IUA7 TRIM25 E3 ubiquitin/ISG15 ligase TRIM25 1 EPPADVWT(1)PPAR 115.24 0.0017894000000000002 5573200.0 5715.6 10345.0 9777.0 8152.2 9831.3 8392.5 7976.6 7514.6 7892.9 6142.9 True False 6683.138191754272 11371.983232276789 10010.120759478981 7695.458663789002 7904.927339577558 7952.382525848125 7220.998702417012 7317.349712376843 8008.318730600224 7256.559142830358 0.9209789461107558 1.5671316127165533 1.3794583028196226 1.060483145292392 1.0893492609907 1.0958888874633175 0.9950995451544717 1.0083773270981395 1.1035972522200996 1.0 12.825069909424506 -5.771174313308727 24.499093731708204 1.0519624911035819 1.3169838144679478 0.33109791889641615 0.1540117090285566 152.98865051975554 385014.26733417297 0.04184874630109401 0.06298802078636742 1.6936578784664791e-06 5.771174313308727 0.2650213233643659 EPPADVWT(ph)PPAR ddPTM_PC-9_Lapatinib_30min_R1 1 EPPADVWTPPAR 12 0 A0A3B3IUA7;Q14258 A0A3B3IUA7 TRIM25 E3 ubiquitin/ISG15 ligase TRIM25 1 EPPADVWT(1)PPAR 127.78 0.00054818 7919900.0 10160.0 9002.0 12923.0 12714.0 12741.0 12728.0 10594.0 11087.0 14155.0 9669.3 True False 10015.116536884196 8981.156422081229 11860.520824222589 13649.029972660683 11991.599429769782 12183.653110417152 11142.505483159894 11602.142495083419 12560.714841241926 11340.62562146762 0.8831185219557679 0.7919454112901889 1.045843608642791 1.2035517640952094 1.0574019309014027 1.0743369472803772 0.9825300521399201 1.0230601804825257 1.1075857065120551 1.0 13.46921261031392 -5.297409671035567 7.644795867230708 1.0655000140928486 0.8376077551238909 0.6764331113708375 0.06201200842142369 0.12959288006013636 24.60377976257858 0.0168280479491369 0.035895727748663474 5.041854737986323e-06 5.297409671035567 -0.2278922589689577 EPPS(ph)PQGR ddPTM_PC-9_AZD4547_30min_R2 1 EPPSPQGR 8 0 Q8WXG6-4;Q8WXG6-7;Q8WXG6-2;Q8WXG6;A0A0A0MRB5;Q8WXG6-6;Q8WXG6-8;Q8WXG6-5;Q8WXG6-3 Q8WXG6-4 MADD MAP kinase-activating death domain protein 1 EPPS(1)PQGR 68.786 0.042647000000000004 6558800.0 20382.0 12205.0 19260.0 31172.0 24329.0 16741.0 18664.0 26437.0 19625.0 23447.0 True False 26863.052028063463 16150.027568216601 19004.599815739562 23985.777002599123 20951.338299108633 15694.182623532877 20325.05984304108 22351.769111823738 20662.337434768422 22626.127666711356 1.1872580418427354 0.7137777973372481 0.8399404483030493 1.0600920031883383 0.9259798498323355 0.6936309586294305 0.8983004136825534 0.9878742593991783 0.9132069675876462 1.0 14.465702076215146 -7.708877023021406 8.48162084944518 0.9627918182767061 0.891773974779387 0.03848974287425566 0.13962387742059698 0.9505718992143465 139.46367159650055 0.06622838659198228 0.037921333333744936 1.954892934583907e-08 7.708877023021406 -0.0710178434973191 EPPS(ph)PQGR ddPTM_PC-9_Lapatinib_30min_R1 1 EPPSPQGR 8 0 Q8WXG6-4;Q8WXG6-7;Q8WXG6-2;Q8WXG6;A0A0A0MRB5;Q8WXG6-6;Q8WXG6-8;Q8WXG6-5;Q8WXG6-3 Q8WXG6-4 MADD MAP kinase-activating death domain protein 1 EPPS(1)PQGR 76.92699999999999 0.024263999999999997 5016100.0 21914.0 20582.0 24419.0 16669.0 23892.0 17154.0 15288.0 17502.0 22600.0 13675.0 True False 21601.50234146459 20534.34364355431 22411.364080065894 17894.893866153914 22486.719533479278 16420.363407927092 16079.537835241492 18315.206814192275 20054.550011449508 16038.705529207875 1.3468357718848556 1.2802993113228178 1.3973299802314378 1.1157318047622833 1.4020283303118828 1.023796052494647 1.002545860447357 1.1419379687992086 1.2503845759203218 1.0 13.969270087305274 -6.767549871067904 24.999998207254357 1.0875298104612312 1.3011131539945975 0.5458226159296614 0.102351989545046 123.0236938795153 503326.5223584979 0.03564485964151216 0.032222832419699074 1.7078515921402172e-07 6.767549871067904 0.21358334353336628 EPPS(ph)SPLQPQK ddPTM_PC-9_AZD4547_30min_R2 1 EPPSSPLQPQK 11 0 Q92615;H0Y4V9;A0A087X183 Q92615 LARP4B La-related protein 4B 1 EPPS(0.925)S(0.075)PLQPQK 162.49 0.0014311 9222400.0 39224.0 40987.0 43324.0 30873.0 35070.0 45973.0 46551.0 48242.0 42391.0 33636.0 True False 51696.416090116836 54235.246205530006 42749.495452601266 23755.70683309518 30201.13585226439 43098.30104245127 50693.94881876373 40787.30739087649 44631.701717058284 32458.413878001607 1.5926969285813934 1.6709148638432838 1.3170543580250034 0.7318813212002141 0.9304563052827709 1.32780058829864 1.561812262586284 1.2566019875210144 1.375042597115536 1.0 14.986304882015416 -5.376019146685939 4.5728105235148755 1.1825670609814096 1.6284908728605831 0.3898733300761308 0.22694291275767084 0.25006165424692434 8.210854735734143 0.0677102572411296 0.14824948579571753 4.207080802716154e-06 5.376019146685939 0.4459238118791735 EPPS(ph)SPLQPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EPPSSPLQPQK 11 0 Q92615;H0Y4V9;A0A087X183 Q92615 LARP4B La-related protein 4B 1 EPPS(0.5)S(0.5)PLQPQK 94.191 0.0067352 5723200.0 19705.0 25011.0 25063.0 25933.0 28570.0 19840.0 24587.0 20405.0 18063.0 19302.0 True False 23040.667308509706 27493.926788059434 25660.5969719568 24480.05808592038 22971.91359146105 18799.555473676122 22257.941365535076 19869.3903708846 18327.137203161306 22801.29980545208 1.0104979762162678 1.2058052401681632 1.125400621495316 1.0736255518234485 1.0074826342122905 0.8244949031011342 0.9761698480107226 0.8714148114544583 0.8037759846822002 1.0 14.476828448212693 -6.4173011541909375 2.2968604155969317 0.8921261009064337 1.1178248175540264 0.6391083336082908 0.07334206908250272 0.18178137425850602 1.8873023179383763 0.024757995324847328 0.028501535967249286 3.8255937196816004e-07 6.4173011541909375 0.22569871664759267 EPPSS(ph)PLQPQK ddPTM_PC-9_AZD4547_30min_R2 3 EPPSSPLQPQK 11 0 Q92615;H0Y4V9;A0A087X183 Q92615 LARP4B La-related protein 4B 1 EPPS(0.044)S(0.956)PLQPQK;EPPS(0.225)S(0.775)PLQPQK;EPPS(0.227)S(0.773)PLQPQK 174.21 0.0009062999999999999 48876900.0 150557.0 172914.0 202099.0 150339.0 154366.0 194342.0 191590.0 213616.0 180842.0 150504.0 True False 198430.99421985814 228805.06898243388 199419.0352108592 115680.66626439607 132934.94545111601 182189.76401783762 208641.1388409907 180606.5556073436 190400.93892373968 145234.90076985245 1.3662762405456748 1.575413814238848 1.373079295360762 0.7965073522356054 0.9153099203184801 1.2544489172512738 1.4365771432006926 1.2435478982668435 1.310986119138539 1.0 17.148028657228252 -5.537085020043029 24.9983985466541 1.1496769916607217 1.471695511134368 0.35772887577122336 0.187630451751771 265.4747177001625 467146.96543402947 0.056565187586526636 0.09802678496992767 2.9034542015469207e-06 5.537085020043029 0.32201851947364624 EPPSS(ph)PLQPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EPPSSPLQPQK 11 0 Q92615;H0Y4V9;A0A087X183 Q92615 LARP4B La-related protein 4B 1 EPPS(0.319)S(0.681)PLQPQK;EPPS(0.078)S(0.922)PLQPQK;EPPS(0.209)S(0.791)PLQPQK 163.71 0.00085531 38952700.0 129278.0 179285.0 169968.0 164578.0 183201.0 141239.0 189390.0 126391.0 131630.0 124750.0 True False 151162.21204311206 197083.22994671317 174020.68172722976 155357.22822907506 147304.07916938202 133832.1782029507 171449.60813514 123073.37017233414 133554.83973050548 147366.18747954333 1.025759128525298 1.3373707586353303 1.180872523769311 1.0542257412382403 0.9995785443647314 0.9081606879565141 1.1634256885348264 0.8351533840788179 0.9062787197982233 1.0 17.169046016838145 -5.9421301102088195 2.3489194621550924 0.9670462676307614 1.199567956272268 0.43976839854361094 0.10699971139156192 0.2617047622749041 2.923031582589172 0.032740829585977196 0.052601782210950965 1.142535991350723e-06 5.9421301102088195 0.23252168864150669 EPPSS(ph)PLQPQK ddPTM_PC-9_Lapatinib_30min_R1 2 EPPSSPLQPQK 11 0 Q92615;H0Y4V9;A0A087X183 Q92615 LARP4B La-related protein 4B 1 EPPS(0.225)S(0.775)PLQPQK;EPPS(0.054)S(0.946)PLQPQK 184.98 0.0011784 39633000.0 103033.0 218478.0 207298.0 203451.0 264395.0 275330.0 305330.0 275700.0 253900.0 231696.0 True False 101563.73052606173 217972.12761424796 190254.75863342054 218413.46523264062 248843.80592056987 263554.777725578 321138.49340883596 288510.02849233325 225303.10831447033 271744.3448844861 0.37374735643251283 0.8021220375603555 0.7001240769676167 0.803746128831069 0.9157276337299646 0.9698629711599358 1.1817669786112621 1.061696531771338 0.8290995288613746 1.0 18.05189048690375 -4.623684156922073 0.528157070734739 1.0286478998415296 6.099930412619863e-18 0.7239778014424519 0.11124111198923846 2.7640225643826306 0.5225624333490296 0.06753518678760644 1.8234261534320821 2.3785694856541866e-05 4.623684156922073 -1.0286478998415296 down EPRPNS(ph)SPSPSPGQASETPHPRPS ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EPRPNSSPSPSPGQASETPHPRPS 24 2 O00204-2;O00204 O00204-2 SULT2B1 Sulfotransferase family cytosolic 2B member 1 1 EPRPNS(0.695)S(0.282)PS(0.018)PS(0.005)PGQASETPHPRPS 64.257 0.0040569000000000004 6776900.0 2955.6 3316.6 7386.5 4631.8 8695.3 6807.4 6490.6 6026.0 6877.8 4717.8 True False 3455.924704239091 3645.8501293541985 7562.622173457245 4372.295262498206 6991.518384733333 6450.407960257196 5875.76338012535 5867.823885074765 6978.374813480753 5573.099793915749 0.6201081681709675 0.6541871246114124 1.3569866776319872 0.7845356128866593 1.2545116081298413 1.1574183486359277 1.0543079430481443 1.0528833328053395 1.2521532130286215 1.0 12.444264271722165 -5.2360528557541075 21.794403693715918 1.1086444642330164 0.6371464105253021 0.6132235334783482 0.15146529756038923 93.92072220656178 80628.92927998892 0.03595577197728987 0.09496695989387059 5.806937399635022e-06 5.2360528557541075 -0.47149805370771436 EPRPNSSPS(ph)PSPGQASETPHPRPS ddPTM_PC-9_AZD4547_30min_R2 1 EPRPNSSPSPSPGQASETPHPRPS 24 2 O00204-2;O00204 O00204-2 SULT2B1 Sulfotransferase family cytosolic 2B member 1 1 EPRPNS(0.177)S(0.177)PS(0.482)PS(0.164)PGQASETPHPRPS 67.13600000000001 0.00035507 14256000.0 4549.3 2563.8 11504.0 20953.0 17660.0 14232.0 11534.0 18407.0 11653.0 14860.0 True False 5995.882768681643 3392.498212158434 11351.449443419926 16122.609570622979 15208.213833789257 13342.070790163063 12560.503655681305 15562.62110078072 12268.95378992899 14339.755923031984 0.4181300435561304 0.2365799132403313 0.7916068798066255 1.1243294277225069 1.0605629492871904 0.930425236090213 0.8759217188283581 1.0852779631893605 0.8555901408491237 1.0 13.807732847687724 -5.40621019618995 3.856696952518063 0.9884695134130406 0.330525120053867 0.885090703289461 0.09402406353195283 0.06683613346774277 1.7250790800468832 0.025165814305964967 0.056344859913470935 3.924549433470894e-06 5.40621019618995 -0.6579443933591735 down EPRPNSSPS(ph)PSPGQASETPHPRPS ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EPRPNSSPSPSPGQASETPHPRPS 24 2 O00204-2;O00204 O00204-2 SULT2B1 Sulfotransferase family cytosolic 2B member 1 1 EPRPNS(0.189)S(0.189)PS(0.601)PS(0.021)PGQASETPHPRPS 63.522 0.0052773 4707100.0 2865.3 3429.1 6234.9 4927.3 9544.4 6082.2 6507.7 4398.0 4789.3 3801.0 True False 3350.3386977453843 3769.518385867602 6383.563661989928 4651.239355522137 7674.243335048681 5763.238724898835 5891.243544332068 4282.557160066188 4859.334452034569 4490.091211300555 0.7461627258959308 0.8395193345695444 1.4217002197915103 1.0358897262077902 1.709150877767099 1.283546024720846 1.312054314064963 0.9537795466800205 1.0822351313943714 1.0 12.132529036700763 -5.152339986673919 5.698558908799155 1.2381626602065865 0.7721943481804006 0.39008172173400746 0.21633374017623422 0.22180134772511625 9.717564908581506 0.05644408980086654 0.15629769962691248 7.041416171130261e-06 5.152339986673919 -0.46596831202618594 EPRPNSSPS(ph)PSPGQASETPHPRPS ddPTM_PC-9_Lapatinib_30min_R1 1 EPRPNSSPSPSPGQASETPHPRPS 24 2 O00204-2;O00204 O00204-2 SULT2B1 Sulfotransferase family cytosolic 2B member 1 1 EPRPNS(0.057)S(0.077)PS(0.817)PS(0.05)PGQASETPHPRPS 85.805 6.6947000000000005e-06 9384900.0 8191.9 6224.9 11892.0 7048.2 11752.0 12480.0 8732.6 9786.4 12341.0 4646.2 True False 8075.082003789531 6210.486626506714 10914.285664447496 7566.54814010595 11060.770465320973 11946.259492300918 9184.731299060037 10241.111871009682 10951.02662350877 5449.28947932765 1.4818596138860032 1.1396874124721637 2.002882340138431 1.3885384817250586 2.0297637898080034 2.1922600253886464 1.6854915368146814 1.8793481076496712 2.009624679520593 1.0 12.411852417033213 -5.260074345549568 24.99695002185063 1.812111745943762 1.3107734990776079 0.21810251648786028 0.3442853645232492 152.69361040052132 2796101.7762291087 0.08405820647225079 0.1990758288849711 5.494468076809201e-06 5.260074345549568 -0.501338246866154 EPRPNSSPSPS(ph)PGQASETPHPRPS ddPTM_PC-9_AZD4547_30min_R2 1 EPRPNSSPSPSPGQASETPHPRPS 24 2 O00204-2;O00204 O00204-2 SULT2B1 Sulfotransferase family cytosolic 2B member 1 1 EPRPNS(0.06)S(0.256)PS(0.256)PS(0.428)PGQASETPHPRPS 67.979 0.00032394 13903000.0 7402.1 7678.8 30938.0 32746.0 37904.0 27072.0 20625.0 34944.0 21775.0 31079.0 True False 9755.813826755402 10160.821932881732 30527.74190546989 25196.915620656717 32641.683870665205 25379.183560377634 22460.58504408072 29544.207733236337 22925.98204545645 29990.933669711376 0.325292101079469 0.33879645244734113 1.017899017138658 0.8401510902644467 1.0883850509672826 0.846228524922808 0.748912497738083 0.9851046339072065 0.7644304208044712 1.0 14.8722388160507 -5.254108460687311 24.720507671402643 0.9065041274832148 0.3320441678541463 0.8254028662791553 0.10656272894533328 175.88541451118525 593096.7817725966 0.02650590375258468 0.06711400275211454 5.57046614758693e-06 5.254108460687311 -0.5744599596290685 EPRPNSSPSPS(ph)PGQASETPHPRPS ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EPRPNSSPSPSPGQASETPHPRPS 24 2 O00204-2;O00204 O00204-2 SULT2B1 Sulfotransferase family cytosolic 2B member 1 1 EPRPNS(0.064)S(0.064)PS(0.041)PS(0.829)PGQAS(0.002)ETPHPRPS;EPRPNS(0.005)S(0.019)PS(0.07)PS(0.906)PGQASETPHPRPS 101.05 1.0208e-06 11794000.0 9113.4 15096.4 32176.0 22805.6 31349.0 28380.0 29666.2 22652.6 22778.6 13425.7 True False 10656.118622145252 16595.070823368133 32943.19786815952 21527.876168752773 25206.388490679466 26891.70283986533 26856.002771311527 22057.993252413653 23111.69393212258 15859.67313221728 0.6719002676353053 1.0463690320109416 2.077167517484256 1.3573972167825532 1.5893384611739132 1.695602590020448 1.693351593530408 1.3908226902611964 1.4572616812116748 1.0 13.953075416960278 -5.032438041745733 7.021173344809967 1.5555499314034273 0.7578017845272631 0.5267267202186559 0.26538770354850666 0.11796842264960364 20.85447515430251 0.063445754950804 0.183229311016767 9.280298772797443e-06 5.032438041745733 -0.7977481468761642 EPRPNSSPSPS(ph)PGQASETPHPRPS ddPTM_PC-9_Lapatinib_30min_R1 1 EPRPNSSPSPSPGQASETPHPRPS 24 2 O00204-2;O00204 O00204-2 SULT2B1 Sulfotransferase family cytosolic 2B member 1 1 EPRPNS(0.091)S(0.091)PS(0.161)PS(0.649)PGQAS(0.008)ETPHPRPS 52.91 0.0047856 7813700.0 7121.3 8319.5 12221.0 8280.4 7687.9 10239.0 8548.9 7252.0 8492.9 8096.9 True False 7019.748956113525 8300.236708898557 11216.23655442422 8889.36823860465 7235.712836992943 9801.101838274775 8991.520211911044 7588.954394727602 7536.340167798208 9496.43837655892 0.739198073821142 0.8740368104095663 1.1810992826648004 0.9360739138314459 0.7619396399026431 1.0320818658148607 0.9468307859613748 0.7991369073125599 0.7935964904906841 1.0 13.213170819166956 -7.7472962059624075 24.84868000310469 0.8472750163763194 0.9307312642681118 0.036669959976247224 0.13044433978787887 607.5083968673399 1067358.8317898554 0.06373077456094912 0.03656448523533471 1.7893850066133622e-08 7.7472962059624075 0.0834562478917924 EPRS(ph)SETSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EPRSSETSR 9 1 I3L308;Q9UNE2-2;Q9UNE2 I3L308 RPH3AL Rab effector Noc2 1 EPRS(0.968)S(0.011)ET(0.011)S(0.011)R 56.225 0.041346 2810100.0 1482.6 931.86 1289.3 1758.3 1226.8 1403.8 1152.1 2043.2 1198.2 962.69 True False 1733.5748973152238 1024.3689023518075 1320.0418016974788 1659.7881514855123 986.4173466574875 1330.182256751337 1042.9647475183206 1989.5681649493476 1215.7214082283053 1137.2180763501535 1.5243997025434635 0.9007673406313326 1.160763998699431 1.459516152620896 0.8673950644746576 1.1696808944688013 0.9171193891550383 1.7495045201310646 1.0690310271272723 1.0 10.151293220951139 -9.73403102490664 9.490026071096318 1.0000388629949561 1.1964494596982016 0.044944615007211364 0.2783129195922356 0.0 0.0 0.2584854174517052 0.0626919222844268 1.8448836206211876e-10 9.73403102490664 0.19641059670324545 EPS(ph)EVPTPK ddPTM_PC-9_AZD4547_30min_R2 1 EPSEVPTPK 9 0 P17096;P17096-3;P17096-2 P17096;P17096-2 HMGA1 High mobility group protein HMG-I/HMG-Y 1 EPS(0.992)EVPT(0.008)PK 79.65899999999999 0.041244 0.0 17887.0 21613.0 27293.0 22765.0 30569.0 27957.0 23972.0 26101.0 24153.0 23010.0 True False 23574.69392728737 28598.979584749293 26931.076987070614 17516.8809657439 26325.022009349013 26208.844370474206 26105.461560082556 22067.69019131185 25429.67827067322 22204.426903698903 1.061711433919522 1.287985486352956 1.2128697175509775 0.7888913792603163 1.185575386544369 1.1803432029181637 1.1756872480115126 0.9938419166150928 1.1452526282692324 1.0 14.438559715373216 -8.181971362504507 0.014101373258193226 9.236074145947009e-07 2.168901924403629 0.05515290000860018 0.13365123361034909 1802.5116884179922 23.388289312178006 1809.8111180237493 1781.8180586019112 6.577012049207484e-09 8.181971362504507 2.1689010007962146 EPS(ph)PALGPNLDGSGLLPR ddPTM_PC-9_AZD4547_30min_R2 3 EPSPALGPNLDGSGLLPR 18 0 Q9BRZ2 Q9BRZ2 TRIM56 E3 ubiquitin-protein ligase TRIM56 1 EPS(1)PALGPNLDGSGLLPR;EPS(1)PALGPNLDGSGLLPR;EPS(0.999)PALGPNLDGS(0.001)GLLPR 164.5 1.5616e-07 25840200.0 7333.400000000001 7620.499999999999 8897.3 11382.2 8118.5 12837.5 6903.55 13474.1 9444.3 6958.599999999999 True False 9665.268655804173 10083.677598000371 8779.315988607457 8758.209643237007 6991.386410510649 12034.76909560978 7517.952576051559 11391.987449015558 9943.50641707942 6714.981532032999 1.4393589334084078 1.5016687015291732 1.30742220908975 1.304279036577694 1.041162418267138 1.7922266856877243 1.1195790398213434 1.6965031690216084 1.4807943059329556 1.0 12.713167716529094 -11.646773622309924 2.5747771081871513 0.15305303426236638 1.406230138922368 0.23712667403108 0.22014039829339457 13391111.936592218 2823469.2113259407 67431242.99567589 0.05393779490608474 2.2554145494189745e-12 11.646773622309924 1.2531771046600015 EPS(ph)PALGPNLDGSGLLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EPSPALGPNLDGSGLLPR 18 0 Q9BRZ2 Q9BRZ2 TRIM56 E3 ubiquitin-protein ligase TRIM56 1 EPS(1)PALGPNLDGSGLLPR;EPS(1)PALGPNLDGSGLLPR;EPS(1)PALGPNLDGSGLLPR 160.76 5.2452999999999996e-06 27428100.0 6788.969999999999 11163.9 8849.2 8586.4 11224.5 10539.2 15294.5 7728.929999999999 5175.45 7448.4 True False 7938.2085327304285 12272.178212355228 9060.198488777882 8105.331845484397 9025.139800747447 9986.505798798753 13845.694237409038 7526.0537769782495 5251.131165260542 8798.735958498039 0.902198744248429 1.394766051651141 1.029715919594941 0.9211927581093129 1.0257314054333841 1.1349932360629071 1.5736003788176551 0.8553562480425838 0.5968051763377293 1.0 13.103080563253757 -7.978263981830684 24.999915444105095 0.7742949573236139 1.1386411760224213 0.32111685731984996 0.21565025432500637 242.0859945015011 278437.66592948645 0.11777476058079074 0.0565705349135418 1.0513226429519714e-08 7.978263981830684 0.36434621869880746 EPS(ph)PALGPNLDGSGLLPR ddPTM_PC-9_Lapatinib_30min_R1 4 EPSPALGPNLDGSGLLPR 18 0 Q9BRZ2 Q9BRZ2 TRIM56 E3 ubiquitin-protein ligase TRIM56 1 EPS(1)PALGPNLDGSGLLPR;EPS(0.981)PALGPNLDGS(0.019)GLLPR;EPS(1)PALGPNLDGSGLLPR;EPS(1)PALGPNLDGSGLLPR 165.66 1.392e-07 35657500.0 2451.75 5878.15 7597.959999999999 7777.22 9100.6 9892.0 8001.3 7240.599999999999 5299.36 4745.24 True False 2416.7875954041165 5864.53950482746 6973.285057773753 8349.182702845375 8565.320600468005 9468.942219378258 8415.568163338417 7577.024709109855 4702.490272065264 5565.448411365144 0.4342484947787531 1.0537407000038927 1.25296014666737 1.500181492257766 1.539017158613285 1.7013799283525528 1.5121096345360192 1.3614401121097255 0.8449436459535512 1.0 12.442282215677782 -4.729672738969475 1.5838659456045898 1.3912784476517155 5.0235553956170864e-15 0.5513138927600288 0.2463460132423212 0.8892317174291386 1.9484669032489015 0.0716042312342228 2.006336356050075 1.8634908344753518e-05 4.729672738969475 -1.3912784476517104 EPS(ph)PHPGVGLTSGSSR ddPTM_PC-9_AZD4547_30min_R2 1 EPSPHPGVGLTSGSSR 16 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 EPS(1)PHPGVGLTSGSSR 56.9 0.033837 1540900.0 6462.9 4306.3 10829.0 17639.0 12785.0 10060.0 13235.0 18564.0 12159.0 10421.0 True False 8517.967763328988 5698.227260713733 10685.40038445709 13572.601069833372 11010.02343516396 9430.94660968525 14412.889360407677 15695.3603582818 12801.699916909527 10056.163961905533 0.8470394670966489 0.5666402499302509 1.0625722119224799 1.3496797706609303 1.0948532140955347 0.9378274504484301 1.4332392963167828 1.5607701324022267 1.273020205856284 1.0 13.295792457202886 -5.452593512601401 4.284103035085507 1.2475733887558915 0.7132596498302837 0.5427206690286157 0.19129426874967445 0.16772839910598766 5.854950141086816 0.05476036293939228 0.1172769571701486 3.5270083464378752e-06 5.452593512601401 -0.5343137389256079 EPS(ph)TKGLNPNPS(ph)HQMTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EPSTKGLNPNPSHQMTK 17 1 P08912 P08912 CHRM5 Muscarinic acetylcholine receptor M5 2 EPS(0.5)T(0.5)KGLNPNPS(0.5)HQMT(0.5)K 50.827 0.034685 47373000.0 68733.0 103070.0 70528.0 110770.0 118400.0 108230.0 87077.0 84076.0 89584.0 75902.0 True False 80368.13936137018 113302.10843410052 72209.65499892957 104563.9160211855 95200.36994151164 102554.22827197402 78828.43617711378 81869.09408588547 90893.99652372253 89662.43176009842 0.8963412856836614 1.2636519689456185 0.8053501737732739 1.1661954061312727 1.0617643094515947 1.1437814730072122 0.8791690636723731 0.9130813483280839 1.013735571737774 1.0 16.45221600720773 -7.267306532818389 24.94552624528443 0.9442532784559591 1.0594643502210406 0.13658532715540106 0.12826732186114154 879.3822970536107 3738874.982448909 0.049523864838931876 0.03443796971036437 5.403727835304651e-08 7.267306532818389 0.1152110717650815 EPS(ph)TPHR ddPTM_PC-9_AZD4547_30min_R2 1 EPSTPHR 7 0 H7BYJ3;O14578;O14578-4;O14578-3 H7BYJ3 CIT Citron Rho-interacting kinase 1 EPS(0.5)T(0.5)PHR 73.665 0.035695 1509500.0 15155.0 15952.0 27119.0 35943.0 30755.0 25437.0 21495.0 33677.0 22432.0 27897.0 True False 19973.97475641753 21108.172041637947 26759.384340760174 27656.896663814354 26485.199119942703 23846.420368843294 23408.013358667395 28472.993470472746 23617.70972416436 26920.334521185952 0.7419660680924404 0.784097687382974 0.9940212414411451 1.0273608094300886 0.9838361814968977 0.8858144147531477 0.8695290669677821 1.0576760644658731 0.8773185825598687 1.0 14.716408717025818 -5.19477867100649 5.126532384025442 0.9610515807604418 0.7555134125384775 0.6230583692530767 0.062034352920545405 0.13927132098601716 7.154151550614795 0.016303567396640777 0.04523001788547346 6.385888465708098e-06 5.19477867100649 -0.20553816822196436 EPS(ph)TPHR ddPTM_PC-9_Lapatinib_30min_R1 1 EPSTPHR 7 0 H7BYJ3;O14578;O14578-4;O14578-3 H7BYJ3 CIT Citron Rho-interacting kinase 1 EPS(0.5)T(0.5)PHR 69.598 0.046141 1887200.0 12448.0 16941.0 21830.0 16967.0 21857.0 18450.0 15814.0 18061.0 19011.0 17865.0 True False 12270.489237316384 16901.774155351945 20035.221666236877 18214.809780252774 20571.414232515363 17660.936509050644 16632.77154150373 18900.17999492211 16869.78098529497 20952.94144638383 0.585621320458283 0.8066540060068246 0.9562009094286217 0.869319939010109 0.9817912337108013 0.8428857854751779 0.7938155883299289 0.9020299151451122 0.8051271001001363 1.0 14.354865168210626 -4.810721317717401 3.1562015008518545 0.8872877876310875 0.5509923491437067 0.657996082436956 0.06694362549947575 0.19335316196713886 3.0137526190425774 0.01676360496169212 0.1570373479416216 1.5462463315585562e-05 4.810721317717401 -0.33629543848738086 EPS(ph)VPASCAVSATYER ddPTM_PC-9_AZD4547_30min_R2 1 EPSVPASCAVSATYER 16 0 Q92615;H0Y4V9;H0Y641 Q92615 LARP4B La-related protein 4B 1 EPS(1)VPASCAVSATYER 112.34 0.00035800000000000003 5173200.0 1002.3 1666.4 2065.4 5552.9 2258.5 4295.4 2234.6 6908.4 2222.8 1871.5 True False 1321.010550864882 2205.031211771908 2038.0114464916126 4272.764696449787 1944.9462595477357 4026.8079589703807 2433.475071006194 5840.8655192390615 2340.292670063861 1805.9793546402668 0.7314649237106113 1.2209614722927598 1.1284799248979036 2.365898970811258 1.0769482245466475 2.229708744246681 1.347454534711953 3.234181777455869 1.295857931072542 1.0 10.818565685161728 -5.6395245994935745 7.523118717311968 1.8545535520912733 1.0263875425111813 0.21872204609806278 0.6585070138724147 0.31223098422515216 19.1846752145277 0.1692319396119779 0.29412710519113355 2.2933767243443763e-06 5.6395245994935745 -0.828166009580092 EPSAT(ph)PPISNLTK ddPTM_PC-9_AZD4547_30min_R2 1 EPSATPPISNLTK 13 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 EPS(0.001)AT(0.99)PPIS(0.009)NLTK 130.2 0.000204 5061300.0 24747.0 25501.0 25171.0 30852.0 29880.0 31474.0 28115.0 33509.0 28031.0 25553.0 True False 32616.03123042327 33743.69955076537 24837.21609356078 23739.548058648415 25731.677766343302 29505.925804496357 30617.180534028077 28330.954010216814 29512.661433579317 24658.397247727862 1.3227149722161549 1.3684465868467859 1.0072518438257132 0.9627368648558814 1.0435259643127996 1.19658733323453 1.2416533088682107 1.1489373670799856 1.196860490853628 1.0 14.58979140970787 -5.2498586784086685 24.899009555098715 1.1066464412252657 1.3455808183094797 0.5365111596802623 0.09123372739206667 615.0512743040224 1322380.4375202705 0.026219994148502377 0.06809836558015671 5.625243436393215e-06 5.2498586784086685 0.23893437708421406 EPSAT(ph)PPISNLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 EPSATPPISNLTK 13 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 EPS(0.052)AT(0.942)PPIS(0.004)NLT(0.001)K;EPS(0.002)AT(0.997)PPIS(0.001)NLTK;EPS(0.002)AT(0.997)PPISNLTK;EPS(0.191)AT(0.805)PPIS(0.004)NLTK;EPS(0.198)AT(0.801)PPIS(0.001)NLTK 137.93 0.00015125 24656900.0 141319.0 165013.0 153217.0 136058.0 138550.0 112454.0 146315.0 117387.0 115824.0 100292.0 True False 165241.51552252154 181394.40010707497 156870.27435870792 128435.11136598769 111402.1220894968 106556.71427604709 132454.98397113354 114305.71563180746 117517.70688251991 118474.14568896465 1.3947474747472526 1.5310884839237213 1.3240886730725732 1.0840771260184816 0.9403074522433414 0.8994090116150327 1.1180075045138826 0.9648156985398253 0.9919270250831289 1.0 16.854212732244314 -5.722622757509977 2.4498444137184614 0.9871194075553468 1.4616799880096323 0.907015238216584 0.06271761765774035 0.07522889752746949 0.918277076769246 0.018440324183531913 0.03508844331175513 1.8939880847498306e-06 5.722622757509977 0.4745605804542855 EPSAT(ph)PPISNLTK ddPTM_PC-9_Lapatinib_30min_R1 3 EPSATPPISNLTK 13 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 EPS(0.003)AT(0.995)PPIS(0.002)NLTK;EPS(0.026)AT(0.968)PPIS(0.006)NLTK;EPS(0.005)AT(0.992)PPIS(0.003)NLTK 103.3 0.0037496 33505600.0 100713.0 133282.0 131632.0 122533.0 135790.0 121215.0 113747.0 111713.0 122506.0 102836.0 True False 99276.81415149759 132973.39371782154 120809.72507421428 131544.48557810535 127803.09917341164 116030.91701596612 119636.26309165468 116903.59380835677 108708.08423462964 120611.06557964334 0.8231153059993648 1.1024974622250971 1.0016471083612122 1.090650223061352 1.0596299647897496 0.9620254697057393 0.9919178022074188 0.9692609317937051 0.9013110340431095 1.0 16.880002749208188 -6.784151277268795 24.350821943548258 0.9646702409170036 1.023745275786826 0.09355560895704096 0.07664182077980917 384.1449891733197 411861.7841342324 0.026267030414889737 0.023182955682985354 1.6437990409587276e-07 6.784151277268795 0.05907503486982235 EPSATPPIS(ph)NLTK ddPTM_PC-9_AZD4547_30min_R2 1 EPSATPPISNLTK 13 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 EPS(0.021)AT(0.405)PPIS(0.514)NLT(0.061)K 64.73 0.041382 28839000.0 51653.0 59337.0 53203.0 57493.0 70982.0 65725.0 56779.0 78277.0 52620.0 54582.0 True False 68077.5795508569 78516.52485172194 52497.493457777324 44238.877107995395 61127.37453850667 61615.20535999634 61832.22100450229 66181.08827651515 55401.3857741409 52671.1007934678 1.292503451139183 1.4906945871436859 0.9967039356862653 0.8399079654982613 1.1605486427594771 1.1698104735194328 1.173930676842255 1.2564971545975898 1.0518364898310937 1.0 15.684723990791493 -5.261992553557792 24.998224246494154 1.0910143167623658 1.3915990276510048 0.5111829646097839 0.12112423451450074 41.232435846938856 1863428.4882898387 0.033993823439696286 0.07832409215610596 5.470253421466338e-06 5.261992553557792 0.30058471088863903 EPSEVPT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 EPSEVPTPK 9 0 P17096;P17096-3;P17096-2 P17096;P17096-2 HMGA1 High mobility group protein HMG-I/HMG-Y 1 EPS(0.004)EVPT(0.996)PK;EPS(0.006)EVPT(0.994)PK;EPS(0.014)EVPT(0.986)PK 92.611 0.016859 170927000.0 377001.0 475744.0 382209.0 344689.0 415784.0 471973.0 461656.0 474580.0 483653.0 473032.0 True False 496879.47589205945 629518.9443190192 377140.65892907605 265226.2764419637 358059.5685542592 442460.4536991035 502742.489653824 401244.5657634875 509217.91018283134 456471.2936597351 1.088522942830323 1.3790986488370023 0.8262089296029335 0.5810360478870985 0.7844076364222929 0.9693061970046343 1.1013671541601486 0.8790137985381946 1.115552976179954 1.0 18.800164610008977 -5.2693549487901 24.965046270779666 0.8959217459249872 1.2338108009575024 0.38993120528344727 0.1629768602112305 544.5015192057773 1717316.1841679537 0.04594158677866098 0.09845554329592877 5.378300344620104e-06 5.2693549487901 0.3378890550325152 EPSEVPT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EPSEVPTPK 9 0 P17096;P17096-3;P17096-2 P17096;P17096-2 HMGA1 High mobility group protein HMG-I/HMG-Y 1 EPSEVPT(1)PK;EPS(0.001)EVPT(0.999)PK;EPS(0.005)EVPT(0.995)PK;EPS(0.001)EVPT(0.999)PK 101.35 0.0086236 1052580000.0 401839.0 547093.0 382061.0 380523.0 431745.0 278569.0 416724.0 290279.0 268496.0 267822.0 True False 469862.4060179762 601404.7774283225 391170.78321441193 359203.5299822114 347147.6665574146 263960.3512473026 377248.88589950977 282659.483826023 272422.2460554728 316376.0085222146 1.4851391804729226 1.9009177726132618 1.2364110194118767 1.1353690555110143 1.097262931468583 0.8343248038315408 1.1924067430448695 0.8934289459757687 0.8610711264989755 1.0 18.271280675706564 -5.525879111456599 2.3493360260028044 0.9951451482008323 1.6954936959916485 0.7640374780331547 0.15035476476277582 0.13068806281831974 1.426237491298999 0.04157580250955944 0.09841715868168932 2.9793456332205083e-06 5.525879111456599 0.7003485477908161 EPSEVPT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 EPSEVPTPK 9 0 P17096;P17096-3;P17096-2 P17096;P17096-2 HMGA1 High mobility group protein HMG-I/HMG-Y 1 EPS(0.002)EVPT(0.998)PK;EPS(0.04)EVPT(0.96)PK;EPS(0.15)EVPT(0.85)PK;EPS(0.018)EVPT(0.982)PK 115.0 0.0049023999999999995 2117790000.0 423189.0 691500.0 519494.0 596590.0 624350.0 556320.0 552960.0 583920.0 484751.0 517260.0 True False 417154.2472566427 689898.8742356336 476783.208624831 640465.2187658998 587626.9605193285 532527.4904452601 581589.5631459408 611051.0549047618 430153.23772567004 606667.701794375 0.6876157178349898 1.1371940061999035 0.7859050468891333 1.0557100977546028 0.9686142162855734 0.8777910689330811 0.9586624793535915 1.0072252949966216 0.7090425886418245 1.0 19.210546980629744 -4.726160613141631 24.826473222261995 0.9423231902820686 0.687613427358951 0.29414052371160637 0.11932275509430222 6918.549548865048 4868418.18044789 0.02740988300245173 6.117015771363833 1.8786219261635808e-05 4.726160613141631 -0.25470976292311753 EPST(ph)ASGGGQLNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EPSTASGGGQLNR 13 0 A0A075B785;A0A2R8Y566;Q9P260;Q9P260-2 A0A075B785 KIAA1468 LisH domain and HEAT repeat-containing protein KIAA1468 1 EPS(0.043)T(0.651)AS(0.306)GGGQLNR;EPS(0.107)T(0.625)AS(0.268)GGGQLNR 103.11 0.0038652 9938300.0 9472.1 16760.7 15516.0 13077.699999999999 13354.8 10102.900000000001 13343.3 8432.3 9701.4 6976.3 True False 11075.539447497316 18424.591528392604 15885.960284757688 12344.99886747546 10738.02280823395 9573.086138861012 12079.326026873721 8210.961059760364 9843.264621754373 8241.047965639582 1.343947941290468 2.2357097792917267 1.9276626408428859 1.4979889595288107 1.30299239283709 1.1616345613780263 1.4657512099477574 0.9963491407883242 1.1944190426745616 1.0 13.008612092786331 -6.04041124972397 2.3005490346098845 1.1926439586071491 1.8744202752280177 0.5905969766188698 0.24142916695998135 0.20154905113773616 2.1235127182269977 0.07462011233903332 0.11165731109497633 9.111476308731269e-07 6.04041124972397 0.6817763166208686 EPST(ph)ASGGGQLNR ddPTM_PC-9_Lapatinib_30min_R1 1 EPSTASGGGQLNR 13 0 A0A075B785;A0A2R8Y566;Q9P260;Q9P260-2 A0A075B785 KIAA1468 LisH domain and HEAT repeat-containing protein KIAA1468 1 EPS(0.211)T(0.784)AS(0.005)GGGQLNR 134.06 0.00010982 5164300.0 6631.8 8813.3 8592.5 4475.5 7069.8 9414.7 7969.7 6920.3 5619.7 3519.6 True False 6537.22931587683 8792.893345337538 7886.057818009179 4804.643199830339 6653.968263761589 9012.055227737617 8382.33206995841 7241.842401797214 4986.750207935522 4127.9581704277925 1.5836471800292873 2.1300829568305204 1.9104015817078697 1.1639272980647524 1.6119272504818085 2.1831750360986995 2.0306242757032886 1.7543400642179279 1.2080428148860651 1.0 12.011212636328743 -8.333803890538595 3.1995930337683305 1.01694082735317 1.8083762641289585 0.492643214334466 0.2847102533336265 0.22210344181983396 4.189821860594969 0.29026692997201703 0.0794009535863199 4.636562404920258e-09 8.333803890538595 0.7914354367757885 EPSTAS(ph)GGGQLNR ddPTM_PC-9_AZD4547_30min_R2 1 EPSTASGGGQLNR 13 0 A0A075B785;A0A2R8Y566;Q9P260;Q9P260-2 A0A075B785 KIAA1468 LisH domain and HEAT repeat-containing protein KIAA1468 1 EPS(0.017)T(0.281)AS(0.702)GGGQLNR 102.63 0.0017015999999999997 6887600.0 2296.4 6828.8 8033.9 5239.8 7727.5 9433.7 1874.9 9196.9 3150.0 2256.2 True False 3026.6074319127174 9036.076055537693 7927.365236742988 4031.845064103006 6654.6700113593715 8843.809247692621 2041.7624678374261 7775.730428737445 3316.502569147545 2177.211124733833 1.3901304276509814 4.150298495577624 3.641064087302107 1.8518392719474572 3.0565111190918217 4.061989738718513 0.937788000732834 3.5714177373074185 1.5232801869653279 1.0 11.088265597488167 -8.550331524024891 0.7123230054961428 0.9676692506760327 2.9813567281267392 0.2325277222180675 1.08064062069382 1.1470659913383299 1.3171790239880905 1.0343812129911079 0.40306307226145877 2.8162323050085735e-09 8.550331524024891 2.0136874774507065 EPTPS(ph)IASDISLPIATQELR ddPTM_PC-9_AZD4547_30min_R2 3 EPTPSIASDISLPIATQELR 20 0 A0A499FIX8;H7BXI1;A0A087WXU3;A0FGR8-5;A0FGR8-2;A0FGR8;A0FGR8-6 A0A499FIX8 ESYT2 Extended synaptotagmin-2 1 EPT(0.072)PS(0.928)IASDISLPIATQELR;EPTPS(0.913)IAS(0.086)DISLPIATQELR;EPT(0.308)PS(0.684)IAS(0.005)DIS(0.002)LPIATQELR 232.37 4.1855e-37 6517700.0 10855.17 11907.619999999999 15607.6 17396.42 17483.3 13029.72 16421.4 26192.440000000002 19015.1 12295.9 True False 14306.888258437533 15756.525298799446 15400.633026175326 13385.944141009735 15056.045578725232 12214.96954862307 17882.872787532957 22145.000240394023 20020.199365903973 11865.424283580687 1.2057628885833718 1.3279361042826967 1.2979420421979047 1.1281471122388043 1.26890073366864 1.02945914589216 1.5071414523523767 1.8663471032416565 1.6872721014795755 1.0 13.534476068861228 -7.436839050784531 6.385226876308877 1.6024525604910425 1.2197094059611802 0.2852248857081977 0.22477108091852732 0.23954713060223437 14.642948134182694 0.0909912014105176 0.06055033187621923 3.657303058831101e-08 7.436839050784531 -0.3827431545298623 EPTPS(ph)IASDISLPIATQELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EPTPSIASDISLPIATQELR 20 0 A0A499FIX8;H7BXI1;A0A087WXU3;A0FGR8-5;A0FGR8-2;A0FGR8;A0FGR8-6 A0A499FIX8 ESYT2 Extended synaptotagmin-2 1 EPT(0.008)PS(0.984)IAS(0.005)DIS(0.003)LPIATQELR;EPT(0.002)PS(0.657)IAS(0.335)DIS(0.006)LPIATQELR;EPTPS(1)IASDISLPIATQELR 150.61 1.0094e-14 5149100.0 7551.0 8650.3 10298.900000000001 6612.200000000001 13907.7 5716.18 7758.8 6399.0 6402.23 9067.9 True False 8829.235160951877 9509.0446161589 10544.464834795757 6241.73987104164 11182.586022259815 5416.413458040221 7023.830295152457 6231.03303030094 6495.850501920802 10711.8384885431 0.8242502134806484 0.8877135914931266 0.9843748900876018 0.5826954801192646 1.0439464741949016 0.5056474165320334 0.6557072628255952 0.5816959466822965 0.6064178907167496 1.0 13.38691849275387 -5.7567356083906525 24.999964178430435 0.6964720200519168 0.897672971027877 0.1960059764945017 0.17267869610009365 180.061028476851 956987.5480203441 0.04629141616529758 0.07694879746963577 1.7509122919316169e-06 5.7567356083906525 0.20120095097596025 EPTPSIAS(ph)DISLPIATQELR ddPTM_PC-9_AZD4547_30min_R2 2 EPTPSIASDISLPIATQELR 20 0 A0A499FIX8;H7BXI1;A0A087WXU3;A0FGR8-5;A0FGR8-2;A0FGR8;A0FGR8-6 A0A499FIX8 ESYT2 Extended synaptotagmin-2 1 EPTPS(0.001)IAS(0.995)DIS(0.005)LPIATQELR;EPTPS(0.003)IAS(0.701)DIS(0.291)LPIAT(0.005)QELR 186.36 1.3784999999999999e-11 14091600.0 10645.7 18228.5 23255.5 23667.7 22680.6 16920.9 15045.900000000001 26585.3 16878.6 18854.1 True False 14030.811155684198 24120.506147254087 22947.116875126238 18211.477427319896 19531.79018565347 15862.833448093745 16384.955952229528 22477.152754418716 17770.768337655154 18194.02369774139 0.7711769198929858 1.3257378657942724 1.261244750273404 1.0009593111380124 1.073527797376572 0.8718705500016997 0.9005680230186552 1.2354140638614775 0.9767365720129968 1.0 14.15117701692211 -5.806635933759626 24.999445781551238 1.010775258218805 1.1400220084160333 0.08261135178894574 0.16505871375346748 280.461461318235 155129.5946091624 0.04659860125145409 0.06911727016010477 1.56086041367977e-06 5.806635933759626 0.1292467501972283 EPTPSIAS(ph)DISLPIATQELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EPTPSIASDISLPIATQELR 20 0 A0A499FIX8;H7BXI1;A0A087WXU3;A0FGR8-5;A0FGR8-2;A0FGR8;A0FGR8-6 A0A499FIX8 ESYT2 Extended synaptotagmin-2 1 EPTPS(0.011)IAS(0.964)DIS(0.025)LPIATQELR;EPTPS(0.003)IAS(0.821)DIS(0.172)LPIAT(0.004)QELR;EPTPS(0.001)IAS(0.882)DIS(0.117)LPIATQELR 154.48 1.7594999999999999e-15 7509500.0 5370.700000000001 4875.5 6013.0 6385.5 11258.1 5638.23 4939.6 4323.0 5352.96 4776.3 True False 6279.85343383979 5359.507418943013 6156.372724429491 6027.741137070322 9052.156121947064 5342.551293263348 4471.685328392932 4209.525830597118 5431.236913194621 5642.205380830002 1.1130139741414353 0.9498958398700825 1.0911287889920542 1.068330684584829 1.6043648734770868 0.9468906097277564 0.7925421048276553 0.7460780929562462 0.9626088641948113 1.0 12.462043466805362 -6.985368367061536 24.99911243782204 0.8563711792907 1.1570406669053968 0.38653971005623244 0.17473251297812742 249.87281758840064 426922.62790339167 0.06387727237251017 0.05631295896214484 1.0342645349664501e-07 6.985368367061536 0.3006694876146968 EPTPSIAS(ph)DISLPIATQELR ddPTM_PC-9_Lapatinib_30min_R1 2 EPTPSIASDISLPIATQELR 20 0 A0A499FIX8;H7BXI1;A0A087WXU3;A0FGR8-5;A0FGR8-2;A0FGR8;A0FGR8-6 A0A499FIX8 ESYT2 Extended synaptotagmin-2 1 EPTPSIAS(0.982)DIS(0.018)LPIATQELR;EPTPS(0.001)IAS(0.948)DIS(0.05)LPIATQELR 127.49 4.475e-06 1893300.0 9633.0 9945.400000000001 6182.4 4159.4 6679.099999999999 4504.799999999999 6137.700000000001 6382.0 7598.0 2534.6 True False 9495.631653524157 9922.372037343552 5674.106936754137 4465.296151351649 6286.248469615833 4312.140205201698 6455.480074003254 6678.5310186364495 6742.233229512979 2972.7022328577914 3.1942760861035118 3.3378291063497243 1.9087370655685767 1.5021000428485434 2.1146579701568635 1.4505792600210232 2.1715865123151983 2.246619572191756 2.2680486309694627 1.0 11.537559244478802 -5.26424886778261 23.698108577528956 1.8740188653306729 3.266052796185175 0.6809527062918446 0.3916104236061594 60.829659566823146 513112.68424585916 0.0994780880159926 0.22336336390357417 5.441907208357704e-06 5.26424886778261 1.392033930854502 EPTPSIASDIS(ph)LPIATQELR ddPTM_PC-9_AZD4547_30min_R2 1 EPTPSIASDISLPIATQELR 20 0 A0A499FIX8;H7BXI1;A0A087WXU3;A0FGR8-5;A0FGR8-2;A0FGR8;A0FGR8-6 A0A499FIX8 ESYT2 Extended synaptotagmin-2 1 EPTPSIAS(0.34)DIS(0.659)LPIATQELR 204.47 5.0504e-21 4257700.0 3597.0 3216.9 7115.4 4620.9 5004.7 3481.0 3874.4 6378.3 3933.5 3405.6 True False 4740.771177752149 4256.700015091843 7021.0451468802285 3555.6228971933238 4309.8837924102545 3263.3325197131567 4219.214094292668 5392.680293752897 4141.416779600592 3286.3709805839635 1.4425550875907958 1.2952585207941008 2.136412836031263 1.0819298606883134 1.3114416533840074 0.9929896956226429 1.2838520420305517 1.640922563402948 1.2601793297434405 1.0 11.68227963215611 EPTPSIASDIS(ph)LPIATQELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EPTPSIASDISLPIATQELR 20 0 A0A499FIX8;H7BXI1;A0A087WXU3;A0FGR8-5;A0FGR8-2;A0FGR8;A0FGR8-6 A0A499FIX8 ESYT2 Extended synaptotagmin-2 1 EPTPSIAS(0.335)DIS(0.664)LPIATQELR 159.04 1.0894000000000001e-05 2305800.0 6445.3 5657.6 5983.7 5928.2 7425.9 3239.2 6709.8 4570.9 4480.0 3884.0 True False 7536.361989522327 6219.249138224184 6126.374101308621 5596.062173483719 5970.848202269182 3069.3306497142976 6074.19916925478 4450.918718268877 4545.5115246726855 4588.138454272915 1.642575102001062 1.3555059857516336 1.3352635632874492 1.219680318991274 1.3013661775416903 0.66897079944391 1.3238918637247974 0.9700925032294424 0.990709319253317 1.0 12.16369321225799 -3.820085851252386 0.3930532421472359 0.9838813375818252 2.764646284204424 0.5718014611570105 0.17055448223117306 8.855826354910896 0.6017344147681359 0.13105188519144198 8.639596227903699 0.00015132620775012032 3.820085851252386 1.7807649466225988 EPTPSIASDIS(ph)LPIATQELR ddPTM_PC-9_Lapatinib_30min_R1 1 EPTPSIASDISLPIATQELR 20 0 A0A499FIX8;H7BXI1;A0A087WXU3;A0FGR8-5;A0FGR8-2;A0FGR8;A0FGR8-6 A0A499FIX8 ESYT2 Extended synaptotagmin-2 1 EPTPSIAS(0.395)DIS(0.605)LPIATQELR 151.28 7.5196e-05 2217000.0 9150.1 12854.0 8861.8 3917.7 5294.1 7711.6 7557.4 5820.1 8766.0 2241.3 True False 9019.617896077165 12824.237352747405 8133.217011537242 4205.820727064084 4982.711446601067 7381.7928446176065 7948.685193357799 6090.523093319653 7778.680769927708 2628.7057186554744 3.43120107818326 4.878536711711771 3.0940005774770425 1.5999587543086677 1.8954999075170786 2.808147291737636 3.0238018417000205 2.316928460305105 2.9591295498479506 1.0 11.360136927188623 -5.500083118753463 6.230225582085536 2.3259813641013354 4.128903243634226 0.5582862716646462 0.6814708914763433 0.1242932086185822 17.579992203806746 0.17855795040915623 0.35442481735796155 3.1616724960755248e-06 5.500083118753463 1.8029218795328905 EPVAES(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 EPVAESPK 8 0 A0A0G2JNN3;C9JMY0;A0A087WUE4;Q96PV6-1;Q96PV6 A0A0G2JNN3 LENG8 Leukocyte receptor cluster member 8 1 EPVAES(1)PK;EPVAES(1)PK;EPVAES(1)PK 114.89 0.0036576 80826500.0 826890.0 850525.0 561464.0 542471.0 623890.0 620398.0 768276.0 659500.0 668280.0 666264.0 True False 1089823.8196195385 1125440.5733271134 554018.620505939 417412.6920434025 537273.6426252995 581604.4149856375 836651.0756521771 557589.428802351 703603.9164793404 642938.3001549792 1.6950675039219756 1.750464349465303 0.8616979582214868 0.6492266706506454 0.8356535028256842 0.9046037774471403 1.3012929474733481 0.8672518477557566 1.0943568244569313 1.0 19.294320769794957 -5.259558224314511 24.994960749681052 0.9321528219904828 1.7227660090435262 0.7855624539761985 0.16370905862535506 72.45374656716423 962675.8866954613 0.04562830155734706 0.10884087472372649 5.501001655966976e-06 5.259558224314511 0.7906131870530434 EPVAES(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EPVAESPK 8 0 A0A0G2JNN3;C9JMY0;A0A087WUE4;Q96PV6-1;Q96PV6 A0A0G2JNN3 LENG8 Leukocyte receptor cluster member 8 1 EPVAES(1)PK;EPVAES(1)PK;EPVAES(1)PK 95.618 0.0063714 66350000.0 526520.0 612540.0 392816.0 537810.0 510320.0 375502.0 579070.0 461774.0 358484.0 414207.0 True False 615649.4367559762 673348.9230641676 402182.2232029751 507678.2493035455 410326.45936277293 355810.0140865088 524216.2974962544 449652.9217899961 363726.1503149014 489299.4502391929 1.258226299774131 1.3761489466930783 0.8219551912563344 1.0375614545558312 0.8385998781772303 0.7271825339525149 1.0713608961546808 0.9189728735035044 0.7433610443197814 1.0 18.900358136243867 -5.2602474413193825 24.9984822842929 0.8953806823829211 1.3171876549920614 0.687586251554754 0.11386617512700214 54.65650578248961 1146275.1204190524 0.029074933208411684 0.06871283761470628 5.4922785954468305e-06 5.2602474413193825 0.42180697260914024 EPVAES(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 EPVAESPK 8 0 A0A0G2JNN3;C9JMY0;A0A087WUE4;Q96PV6-1;Q96PV6 A0A0G2JNN3 LENG8 Leukocyte receptor cluster member 8 1 EPVAES(1)PK;EPVAES(1)PK;EPVAES(1)PK;EPVAES(1)PK 115.29 0.0036405 115710000.0 689240.0 1034840.0 672650.0 946930.0 870380.0 746040.0 886960.0 757810.0 674730.0 733530.0 True False 679411.3112088632 1032443.8915603787 617347.3135040877 1016570.39106588 819185.9596329181 714133.6083041803 932882.4488713894 793020.6191214164 598734.8021781121 860319.6831327144 0.7897195943894917 1.2000700574476013 0.7175789716400743 1.181619357311696 0.952187861900341 0.830079355738763 1.0843439562773334 0.9217743528007643 0.6959445586527983 1.0 19.714513319798982 -8.010369705661137 24.8057420206265 0.8349346541709418 0.9698018371730771 0.07166075514746006 0.1653642764346407 979.2793308253285 2342555.629876903 0.0913955645252363 0.039488068109706155 9.764056736711188e-09 8.010369705661137 0.1348671830021353 EPVAES(ph)PKK ddPTM_PC-9_Lapatinib_30min_R1 1 EPVAESPKK 9 1 A0A0G2JNN3;C9JMY0;A0A087WUE4;Q96PV6-1;Q96PV6 A0A0G2JNN3 LENG8 Leukocyte receptor cluster member 8 1 EPVAES(1)PKK 98.182 0.0066757000000000006 6186300.0 17254.0 32293.0 21721.0 28050.0 27211.0 25472.0 27497.0 24724.0 22343.0 21890.0 True False 17007.954796003927 32218.227542576013 19935.183225484707 30112.890572056942 25610.502478884366 24382.62193813215 28920.660116145686 25872.767299399486 19826.496057779474 25673.65733340843 0.662467157488775 1.2549138256453751 0.776483964345181 1.1729100447590635 0.9975400912420108 0.9497136158471551 1.126472155508285 1.0077554188484068 0.7722505523971372 1.0 14.648001208806301 -4.7292993862671056 24.67229133270896 1.0064060491660434 0.6624643708879925 0.3313192896469953 0.14660288484561754 4489.937537646368 3446472.505259123 0.03391459508308928 5.259284496608538 1.8650935223034133e-05 4.7292993862671056 -0.3439416782780509 EPVICTPVSS(ph)GFEK ddPTM_PC-9_Lapatinib_30min_R1 1 EPVICTPVSSGFEK 14 0 Q8TEQ6 Q8TEQ6 GEMIN5 Gem-associated protein 5 1 EPVICT(0.365)PVS(0.263)S(0.372)GFEK 73.91 0.019392 1853800.0 10179.0 14525.0 25104.0 14548.0 17544.0 14090.0 13433.0 10222.0 19095.0 10697.0 True False 10033.845593400021 14491.368254913348 23040.046024242358 15617.908450705341 16512.096412831095 13487.403545394232 14128.495011826206 10696.951437245665 16944.320020735762 12545.962197143448 0.7997669238701035 1.1550623242123943 1.836451095754798 1.2448553730108747 1.3161283410044615 1.0750393898417085 1.1261388158050627 0.852621048043746 1.350579553363692 1.0 13.614935500261808 -6.7652371619112195 23.612046140668756 1.074493440337413 1.2940645166856433 0.11117484583418724 0.26351679387686155 105.37474485101639 655140.075818792 0.09422713953039619 0.0863685491924044 1.7169705184305407e-07 6.7652371619112195 0.21957107634823037 EPVS(ph)PMELTGPEDGAASSGAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EPVSPMELTGPEDGAASSGAGR 22 0 K7EQ54;A0A0C4DFL8;F5GX28;O94953 K7EQ54 KDM4B Lysine-specific demethylase 4B 1 EPVS(0.982)PMELT(0.018)GPEDGAASSGAGR 72.315 0.020759 0.0 2333.3 2643.4 2681.1 3189.0 3848.2 2680.9 4221.8 4163.8 3512.4 3369.1 True False 2728.2816052243415 2905.8192823780055 2745.027592128372 3010.3306688774974 3094.1728345348383 2540.308884545278 3821.8805408149015 4054.504661910774 3563.762205192037 3979.891160219072 0.685516637363059 0.7301253138334707 0.6897242868262942 0.7563851742899911 0.7774516211555194 0.6382860189587314 0.9602977536211134 1.018747623663054 0.8954421268635575 1.0 11.958513261973911 -7.274408208039159 24.6970175362102 0.9701842128800781 0.7175524367685628 0.8756299549812702 0.04719040682952843 214.96968677021508 409372.9977504165 0.019009702062293875 0.012910341450116741 5.316083477361495e-08 7.274408208039159 -0.2526317761115152 EPVS(ph)PMELTGPEDGAASSGAGR ddPTM_PC-9_Lapatinib_30min_R1 2 EPVSPMELTGPEDGAASSGAGR 22 0 K7EQ54;A0A0C4DFL8;F5GX28;O94953 K7EQ54 KDM4B Lysine-specific demethylase 4B 1 EPVS(0.991)PMELT(0.009)GPEDGAASSGAGR;EPVS(1)PMELTGPEDGAASSGAGR 167.89 8.4095e-09 3022000.0 891.48 4972.5 4010.7 3680.61 7386.9 5118.5 8019.0 7631.4 9421.9 7225.0 True False 878.7673317225901 4960.986481759487 3680.9557277497133 3951.294337555031 6952.417065204173 4899.593686806268 8434.184582731657 7985.982703795398 8360.70640499451 8473.831623292645 0.10370365742305496 0.585447847243372 0.43439094513414683 0.466293704337223 0.8204573060070668 0.5782028608331554 0.9953212380982405 0.9424287688043906 0.986650051201492 1.0 13.048798747013397 -5.9969809658143065 0.40224506977412305 1.0574520594146346 0.08759597566830708 0.7936135661970288 0.13171490892513013 0.9861323112974332 0.24959090995621985 0.12220604193662246 0.4217788008770347 1.0069758014511698e-06 5.9969809658143065 -0.9698560837463275 down EPY(ph)IRT(ph)GY(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 EPYIRTGYR 9 1 D6RCM7;Q8TEZ7 D6RCM7 PAQR8 Membrane progestin receptor beta 3 EPY(1)IRT(1)GY(1)R 51.092 0.044481 0.0 519.37 830.17 1193.9 4192.9 3537.4 1187.5 834.94 3568.9 1519.5 2706.2 True False 684.518856432898 1098.506217640833 1178.0681059195977 3226.2916846592416 3046.2930699686353 1113.245437276464 909.2480425068971 3017.4085101633245 1599.817667879269 2611.456761703172 0.2621214589769658 0.4206488247289209 0.4511153020780902 1.2354375274262932 1.166511012030644 0.4262928851061711 0.348176564069892 1.1554503043716464 0.6126150320926165 1.0 11.350639101643242 -5.550043120414289 23.746468658806442 0.8314016123207923 0.3650092058454365 0.35174180435945923 0.2946430133381084 143.50762943644267 125450.09513283544 0.08514850394337878 0.1474879530419738 2.818103112359008e-06 5.550043120414289 -0.46639240647535585 EPYGHLGPAELLEAS(ph)PAAR ddPTM_PC-9_AZD4547_30min_R2 2 EPYGHLGPAELLEASPAAR 19 0 Q9H6W3 Q9H6W3 NO66 Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 1 EPYGHLGPAELLEAS(1)PAAR;EPYGHLGPAELLEAS(1)PAAR 144.95 0.00011373 4104700.0 44667.0 39959.0 53426.0 71481.0 58970.0 54865.0 45610.0 69983.0 51100.0 53613.0 True False 58870.17686868369 52874.96530916568 52717.53633207174 55002.159820441106 50783.03339629403 51434.28287677747 49669.201641722255 59168.73539935545 53801.04167728242 51736.02518852716 1.1378952413557 1.022014449631339 1.018971522067417 1.063130760819218 0.98157972537008 0.9941676556973572 0.9600505926136893 1.1436660467004054 1.0399144789579466 1.0 15.658881597447644 -4.760194002046604 24.8599394515127 1.0260016184695757 1.1378953843802624 0.328477343225578 0.048471339017935704 37.40453515261435 746335.6732432347 0.012460559891486069 0.0754604585862257 1.7370247156693232e-05 4.760194002046604 0.11189376591068667 EPYGHLGPAELLEAS(ph)PAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EPYGHLGPAELLEASPAAR 19 0 Q9H6W3 Q9H6W3 NO66 Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 1 EPY(0.003)GHLGPAELLEAS(0.997)PAAR;EPYGHLGPAELLEAS(1)PAAR 75.539 0.0022703000000000003 4050800.0 44499.0 44494.0 45415.0 48552.0 49645.0 42750.0 44867.0 41581.0 41093.0 34921.0 True False 52031.80180468778 48911.0702693981 46497.8658373466 45831.78884770782 39917.41862961441 40508.11474292608 40616.87295104981 40489.542808711245 41693.90738468182 41251.90086551609 1.2613188898692178 1.1856682781443553 1.1271690482562902 1.1110224713552588 0.9676504062139543 0.9819696521376119 0.9846060932673985 0.9815194441756714 1.010714815799803 1.0 15.33217297905503 -5.6329968521933305 1.0126018225014377 0.9833177915212455 1.256764412260409 0.932125288356948 0.025514818443544283 0.1653007485503434 0.30038720179261613 0.009916633386433109 0.03651895724507794 2.328108131947441e-06 5.6329968521933305 0.27344662073916337 EPYGHLGPAELLEAS(ph)PAAR ddPTM_PC-9_Lapatinib_30min_R1 2 EPYGHLGPAELLEASPAAR 19 0 Q9H6W3 Q9H6W3 NO66 Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 1 EPYGHLGPAELLEAS(1)PAAR;EPY(0.131)GHLGPAELLEAS(0.869)PAAR 136.77 5.9673e-05 4038900.0 36224.0 40647.0 43013.0 34180.0 37165.0 35931.0 30285.0 31731.0 37941.0 28866.0 True False 35707.439117331975 40552.884368844236 39476.63717498154 36693.711221137506 34979.027769201304 34394.314889251946 31853.00911435694 33205.338099710636 33667.68504355776 33855.449638472724 1.0547028469163997 1.1978244212347033 1.166034939619322 1.0838347035107587 1.033187511692409 1.0159166472911607 0.9408532290813162 0.9807974330365026 0.9944539329141978 1.0 15.04710045954137 -6.303153331454198 1.5679395150378928 0.9807766381607519 1.1446782441183871 0.7472276888779805 0.0389796154956246 0.18222818913475922 0.8926845976109103 0.014510823489788025 0.01905790800093764 4.975613855783843e-07 6.303153331454198 0.16390160595763525 EQADFALEALAK ddPTM_PC-9_Lapatinib_30min_R1 2 EQADFALEALAK 12 0 Q7Z406;Q7Z406-6;Q7Z406-2;Q7Z406-4;Q7Z406-5;M0QY43 Q7Z406 MYH14 Myosin-14 0 ; 152.47 0.00071846 6595600.0 34599.0 42228.0 41327.0 35426.0 42574.0 34767.0 37533.0 37226.0 36828.0 35803.0 False True 34105.6119153205 42130.2236604806 37929.25358683334 38031.34621767166 40069.88102370447 33280.09645583542 39476.27508962058 38955.655860194376 32680.042823967357 41991.50084550124 0.8122027369491939 1.0033035926839042 0.9032602508394718 0.9056915197577688 0.9542378866412285 0.7925436287281663 0.9401015513797686 0.9277033465301321 0.7782537457807616 1.0 15.357809732944249 EQAEAEVASLNRR ddPTM_PC-9_AZD4547_30min_R2 2 EQAEAEVASLNRR 13 1 A0A087WWU8;P06753-5;P06753-2;P06753-4;P06753-3;P06753-6;D6R904;A0A494C0G0 A0A087WWU8 TPM3 Tropomyosin alpha-3 chain 0 ; 123.95 0.00010106 24672000.0 47858.0 47444.0 70929.0 113859.0 109332.0 71059.0 57670.0 68700.0 58150.0 81528.0 False True 63075.84849176049 62779.34518201293 69988.4351158147 87610.56665401436 94153.13900769239 66615.66949678157 62802.51827840658 58083.993568948434 61223.69028442215 78673.72953519202 0.8017396513984462 0.7979708798974723 0.8896036266401703 1.1135936629879069 1.1967544892552244 0.846733336405303 0.7982654267116447 0.7382895651713897 0.7781973810843149 1.0 16.263594355862125 -6.980516813906218 24.991601659900986 0.8091102958112589 0.962182149604034 0.18096559809087542 0.13358595801114867 401.938116394377 515575.16719307296 0.052063805902015085 0.045910151736118614 1.0458831978408734e-07 6.980516813906218 0.1530718537927751 EQAEAEVASLNRR ddPTM_PC-9_Lapatinib_30min_R1 1 EQAEAEVASLNRR 13 1 A0A087WWU8;P06753-5;P06753-2;P06753-4;P06753-3;P06753-6;D6R904;A0A494C0G0 A0A087WWU8 TPM3 Tropomyosin alpha-3 chain 0 80.37100000000001 0.0081192 9216400.0 47578.0 35042.0 38875.0 38440.0 27869.0 36251.0 22874.0 30969.0 39625.0 24623.0 False True 46899.5289952634 34960.86240197405 35678.84756183962 41267.00583208092 26229.800212562124 34700.629235208406 24058.303796658434 32407.932797892878 35162.015230251614 28879.052741914835 1.6239981766158758 1.2105958846507499 1.2354576821024192 1.4289598139133666 0.9082638702512702 1.2015847453626545 0.8330710848330699 1.1221951456481207 1.2175612387458172 1.0 14.817735800896605 -1.5228787458799085 0.44754693841203064 1.0507847706047313 12.506437977760568 0.5078988766436617 0.15605981999809232 74.30998817380387 0.900044999009433 0.09762862109053472 776.6773775954249 0.02999999995858311 1.5228787458799085 11.455653207155837 EQALERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EQALERR 7 1 Q12852;Q12852-2 Q12852 MAP3K12 Mitogen-activated protein kinase kinase kinase 12 0 76.774 0.019466999999999998 7304300.0 7714.3 11088.0 11818.0 9817.0 11821.0 12641.0 13907.0 10031.0 11600.0 9012.8 False True 9020.178625629856 12188.743361960855 12099.785940014586 9266.985317143419 9504.75990775852 11978.083706791318 12589.62828203913 9767.696878723036 11769.628054956049 10646.74929471446 0.8472237277257849 1.1448323825951188 1.136477022711663 0.87040514063236 0.8927382100071731 1.125046093903779 1.1824856520561826 0.917434665581181 1.105466817068665 1.0 13.378125388190984 -6.7816617833342825 24.997361844749214 1.0682012265439762 0.9903746108386604 0.12079076161993074 0.11605336108532446 654.7141442916301 809301.2589112967 0.042853241903168415 0.03783838007121008 1.653248801977369e-07 6.7816617833342825 -0.0778266157053158 EQAPDIS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 EQAPDISPK 9 0 Q7Z333-3;Q7Z333;Q7Z333-4 Q7Z333-3 SETX Probable helicase senataxin 1 EQAPDIS(1)PK 80.905 0.018008 11493000.0 100250.0 144920.0 81106.0 105070.0 91227.0 94307.0 100360.0 89898.0 87856.0 104810.0 True False 132127.41467046246 191762.55593494052 80030.48144628103 80847.73481531802 78561.70574264375 88409.96838166878 109291.84557691855 76006.329750529 92499.88879842112 101140.63380168125 1.306373212269371 1.8959991521405006 0.7912792162565101 0.7993595825575507 0.7767571033486823 0.8741290721494287 1.0805928484808625 0.7514915310849629 0.9145670273314374 1.0 16.62600319874707 -5.272170620972877 24.99994139098994 0.8659592370376418 1.6011861860325176 0.7572973160126781 0.16473189564602891 265.0051766983064 617367.4366195479 0.04052199532830197 0.08571881923374804 5.343543867152527e-06 5.272170620972877 0.7352269489948758 EQDLPLAEAVRPKT(ph)PPVVIK ddPTM_PC-9_Lapatinib_30min_R1 1 EQDLPLAEAVRPKTPPVVIK 20 2 Q96A49 Q96A49 SYAP1 Synapse-associated protein 1 1 EQDLPLAEAVRPKT(1)PPVVIK 62.589 0.0045966 193790000.0 1275500.0 749720.0 1046500.0 816950.0 909710.0 933560.0 685820.0 633340.0 1005000.0 683360.0 True False 1257311.1361019476 747984.0694026599 960460.8096068223 877031.2282653105 856202.6463586736 893633.8150346512 721328.4038569673 662767.2885213424 891806.3168808297 801477.8654800382 1.5687409350336732 0.9332560531221424 1.1983622392760187 1.0942675600155474 1.0682798405740854 1.1149825260606754 0.8999979100170582 0.8269314937654376 1.112702365581475 1.0 19.6123031522675 -4.7551576305343914 24.996679919111795 1.02966128852868 1.5687418295290032 0.6936054789737706 0.10788267209225733 127.39571953587867 506891.9123921888 0.028410239599310896 0.25886491201200146 1.757285677793069e-05 4.7551576305343914 0.5390805410003232 EQDNSESPNGRTS(ph)PLVSQNNEQGSTLR ddPTM_PC-9_AZD4547_30min_R2 2 EQDNSESPNGRTSPLVSQNNEQGSTLR 27 1 A0A1W2PNZ9;Q15652-3;Q15652;H7BXU7 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 EQDNS(0.024)ES(0.253)PNGRT(0.185)S(0.531)PLVS(0.007)QNNEQGSTLR;EQDNSES(0.005)PNGRT(0.095)S(0.867)PLVS(0.033)QNNEQGSTLR 79.332 1.3633e-05 22526000.0 24199.0 23671.0 36297.0 59855.0 44674.0 35224.0 25336.6 34850.0 29069.6 33586.0 True False 31893.778629531364 31322.18783836584 35815.6780639615 46056.35450053163 38471.7862293715 33021.43771168521 27591.508316502088 29464.733273331232 30606.159709235366 32410.164362782773 0.9840671670939014 0.9664310087342144 1.1050754838222712 1.4210466193568287 1.1870284210452635 1.0188605445520165 0.8513226902417674 0.9091201434068061 0.944338305929143 1.0 14.984158716612804 -6.979288619377681 4.686521242737558 0.9195635541255973 1.1367391585645437 0.3889910749229901 0.12197571501032514 0.22237488252787507 12.431436102274562 0.05111657699634852 0.0432279514994664 1.0488451652464639e-07 6.979288619377681 0.21717560443894635 EQDNSESPNGRTS(ph)PLVSQNNEQGSTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EQDNSESPNGRTSPLVSQNNEQGSTLR 27 1 A0A1W2PNZ9;Q15652-3;Q15652;H7BXU7 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 EQDNS(0.019)ES(0.038)PNGRT(0.202)S(0.501)PLVS(0.206)QNNEQGS(0.017)T(0.017)LR;EQDNS(0.005)ES(0.169)PNGRT(0.214)S(0.612)PLVSQNNEQGSTLR 93.39200000000001 2.3809e-08 17855100.0 21139.8 13232.599999999999 22503.2 31138.2 30897.3 32097.0 32441.0 26996.0 28823.0 26163.0 True False 24718.350609917943 14546.24507679322 23039.76163186125 29393.627605406487 24843.195863123874 30413.77681646081 29367.953627499206 26287.383604626346 29244.481847241223 30906.144793805972 0.7997875754103064 0.4706586723721198 0.7454751081240887 0.9510609557261048 0.8038270715700135 0.9840689293138936 0.9502302478497725 0.8505552465377276 0.9462351918153904 1.0 14.915606084417348 -5.5895917199662986 4.3099940415347735 0.9176434215145941 0.6282059385959822 0.6214768172370404 0.09319928632115654 0.1199083540896752 4.389921514756146 0.024059125896644475 0.04418953968840749 2.5728133468061743e-06 5.5895917199662986 -0.28943748291861193 EQDNSESPNGRTS(ph)PLVSQNNEQGSTLR ddPTM_PC-9_Lapatinib_30min_R1 2 EQDNSESPNGRTSPLVSQNNEQGSTLR 27 1 A0A1W2PNZ9;Q15652-3;Q15652;H7BXU7 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 EQDNS(0.004)ES(0.012)PNGRT(0.12)S(0.845)PLVS(0.018)QNNEQGS(0.001)T(0.001)LR;EQDNS(0.002)ES(0.005)PNGRT(0.077)S(0.819)PLVS(0.094)QNNEQGS(0.001)T(0.001)LR 60.196999999999996 0.00096284 20737000.0 42746.0 31058.0 32893.0 28147.5 29232.0 31064.0 20381.8 14842.0 28984.0 22002.0 True False 42136.43420134364 30986.087109197837 30188.664510651844 30217.561047307423 27512.631232323227 29735.46513372081 21437.06987508668 15531.61350338487 25719.516704949223 25805.016384177838 1.632877637976595 1.2007776568666213 1.169875812563398 1.1709956156367762 1.0661737556265378 1.1523133599695328 0.8307326589503995 0.6018834970749318 0.9966867031605127 1.0 14.655363926170816 -1.5228787452803538 0.3214296090572482 0.8435095041334838 7.936663070205813 0.6752899525396368 0.1448385990257521 34.68044626571877 0.4948383917686702 0.14386833856811773 144.8246288135663 0.029999999999998875 1.5228787452803538 7.0931535660723295 EQDRVHS(ph)PCPTSGSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EQDRVHSPCPTSGSEK 16 1 X6RLP6;Q96LT9-2;Q96LT9 X6RLP6 RNPC3 RNA-binding protein 40 1 EQDRVHS(0.981)PCPT(0.011)S(0.005)GS(0.003)EK;EQDRVHS(0.999)PCPTSGSEK;EQDRVHS(1)PCPTSGSEK;EQDRVHS(0.969)PCPT(0.011)S(0.011)GS(0.01)EK 78.67399999999999 0.0045141999999999995 27041300.0 37390.7 38751.8 47053.8 60440.0 62148.5 56756.9 48630.8 61483.0 54861.6 48336.8 True False 43720.207010012346 42598.82260227585 48175.741044530216 57053.742749123834 49970.9475617402 53780.46824918791 44024.138567497575 59869.136396623304 55663.847112049756 57099.87920610175 0.7656795008655702 0.7460405029670133 0.8437100343179379 0.9991920042980934 0.8751497946496576 0.9418665853051554 0.7710023064776136 1.0484984772126387 0.9748505230830936 1.0 15.80120007314208 -2.8340546203032817 0.29445007579689614 0.9825574168912831 2.4750334254344885e-16 0.4792511094084563 0.07613193347898972 23.145809755774337 0.6539454483379772 0.08446353789070157 10.210017906357141 0.0014653635336775164 2.8340546203032817 -0.9825574168912828 EQDRVHS(ph)PCPTSGSEK ddPTM_PC-9_Lapatinib_30min_R1 4 EQDRVHSPCPTSGSEK 16 1 X6RLP6;Q96LT9-2;Q96LT9 X6RLP6 RNPC3 RNA-binding protein 40 1 EQDRVHS(0.992)PCPT(0.005)S(0.002)GS(0.002)EK;EQDRVHS(0.995)PCPT(0.003)S(0.001)GS(0.001)EK;EQDRVHS(0.982)PCPT(0.012)S(0.004)GS(0.002)EK;EQDRVHS(0.982)PCPT(0.012)S(0.005)GS(0.001)EK 66.308 0.012713 24195000.0 72952.0 50354.2 68577.0 58618.0 61757.0 68270.0 50444.0 50176.4 69635.0 53191.3 True False 71911.69110224163 50237.607943652794 62938.86377487529 62928.963263915684 58124.574678933524 65350.25124514288 53055.74349561241 52507.7787219539 61791.97301094177 62385.34533204787 1.152701659652431 0.805278991023639 1.0088725715932372 1.0087138722880251 0.9317023792937865 1.0475256792651255 0.8504520286490621 0.8416684790711613 0.9904885944295434 1.0 15.928919551268404 -7.265074352490183 24.995415698090483 0.9074579855162704 0.9826796935465018 0.10815522680846001 0.09569851728377358 692.3236765363635 4760645.165767003 0.0371003737088346 0.0261682240129242 5.4315733340195834e-08 7.265074352490183 0.07522170803023132 EQELQQTLQQEQSVLDQLR ddPTM_PC-9_Lapatinib_30min_R1 1 EQELQQTLQQEQSVLDQLR 19 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 174.52 1.3492e-28 0.0 3371.1 2804.7 3505.9 2774.1 2958.6 3225.1 3040.9 2236.6 3457.5 2600.1 False True 3323.0274958159716 2798.2058894702545 3217.6584351653605 2978.1165681263155 2784.5809648314016 3087.1699910752964 3198.3429227620254 2340.5206011097293 3068.079940910913 3049.523820584526 1.0896873385232388 0.9175878117698718 1.0551347110148517 0.9765841302907011 0.9131199258176836 1.0123449340636907 1.048800767245351 0.7675036296850777 1.006084923882585 1.0 11.574368269857558 -1.5228787452803376 0.48629387785853084 0.9514561037220693 3.807577190076646 0.11316743015637287 0.08319905861940871 240.65300785068752 2.6532953693355577 0.04707034556854022 697.1654784253717 0.029999999999999995 1.5228787452803376 2.8561210863545767 EQEPMPTVDSHEPR ddPTM_PC-9_Lapatinib_30min_R1 2 EQEPMPTVDSHEPR 14 0 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 0 ; 90.725 0.005731399999999999 2471300.0 13517.1 12307.1 15295.5 12461.4 11162.1 11193.900000000001 10904.0 12241.2 13535.6 10384.6 False True 13324.343675267453 12278.603666095965 14037.963032337439 13377.852926011778 10505.56722353295 10715.162991255396 11468.555766318248 12809.970840697672 12011.078191813085 12179.564273390284 1.093991819098017 1.0081316039295478 1.1525833533312315 1.0983851824025836 0.8625569016853373 0.8797657084224032 0.9416228289360535 1.0517593694779943 0.9861664934972013 1.0 13.57217490098225 -6.238268890178033 24.716597102275383 0.9519380886253883 1.08714222274361 0.5372436986061364 0.061195277176710104 601.8021135214261 641958.7131506485 0.01982420757056785 0.025575811780724836 5.777382343447432e-07 6.238268890178033 0.13520413411822174 EQEVAEERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EQEVAEERR 9 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 0 105.17 0.0016797000000000001 2362100.0 15073.0 11304.0 20162.0 19977.0 22856.0 25382.0 24187.0 30597.0 19971.0 13695.0 False True 17624.56119467985 12426.186414466589 20642.738544810796 18857.75345630786 18377.530873168824 24050.9232375427 21895.8322612843 29793.86117020123 20263.03809357994 16177.79509043964 1.0894291277737338 0.7681013602286206 1.2759920885022051 1.1656565898434426 1.135972533366375 1.4866626201586475 1.353449721601664 1.8416515355549337 1.252521618694163 1.0 13.981727372431537 -6.0570448359829685 0.9095246152009901 1.4340706501937759 0.9518473894888763 0.2772692295373026 0.23380513964452404 0.6915706571992597 1.1736868318795572 0.1046533828981397 0.21924751938392809 8.769102854222415e-07 6.0570448359829685 -0.4822232607048996 EQEVAEERR ddPTM_PC-9_Lapatinib_30min_R1 1 EQEVAEERR 9 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 0 119.27 0.0011056 2645000.0 25812.0 19437.0 20172.0 15494.0 17342.0 16692.0 11845.0 12702.0 18190.0 15114.0 False True 25443.91614665894 19391.994820705724 18513.536026171794 16633.480446468824 16321.977655683822 15978.12207095248 12458.276141969885 13292.181290930783 16141.25065080825 17726.434761860914 1.435365683425664 1.0939591114186324 1.0444026830485034 0.9383432523192073 0.9207704693558102 0.901372570717379 0.7028077732119226 0.749850800203175 0.9105751307384581 1.0 14.113614782193391 -1.5228787452803565 0.5339619010469645 0.8322642372709101 24.73779813701132 0.8051619210582036 0.08489329272840869 51.04654313588432 0.49143626478924785 0.04416521992432339 1390.4489775626212 0.02999999999999869 1.5228787452803565 23.905533899740412 EQEVNILK ddPTM_PC-9_Lapatinib_30min_R1 1 EQEVNILK 8 0 P35579 P35579 MYH9 Myosin-9 0 107.47 0.017553 3880300.0 25901.0 28274.0 24324.0 26199.0 28456.0 28117.0 29549.0 26340.0 22900.0 31742.0 False True 25531.646990338315 28208.533290149382 22324.174613355295 28125.76185730195 26782.274026648513 26914.501453928282 31078.902635632574 27563.852558897528 20320.76085230945 37228.56240644363 0.6858080285667766 0.7577121292566207 0.5996518041612954 0.7554887978278167 0.7194012418275103 0.722953015485493 0.8348133966691486 0.7403952980501524 0.5458379141922567 1.0 15.184122286656459 -6.393552078440338 1.474638357244531 0.7567202689009049 0.6928603552953619 0.08026611019117669 0.11267967425636893 1.372542161764633 6.023668035313201 0.043030470153554184 0.0530276731811761 4.040619185069688e-07 6.393552078440338 -0.063859913605543 EQFEGLGST(ph)PDAK ddPTM_PC-9_AZD4547_30min_R2 3 EQFEGLGSTPDAK 13 0 Q8NCN4 Q8NCN4 RNF169 E3 ubiquitin-protein ligase RNF169 1 EQFEGLGS(0.061)T(0.939)PDAK;EQFEGLGS(0.022)T(0.978)PDAK;EQFEGLGS(0.02)T(0.98)PDAK 150.34 0.00031067 8386600.0 64503.0 62037.1 86631.0 93846.0 102294.0 100494.0 84787.0 95588.0 90938.0 92085.0 True False 85013.61225425263 82089.37937338867 85482.21633631017 72211.25460624661 88092.24382296913 94210.0942936092 92332.87874581662 80817.07099372109 95744.79702639356 88861.13217849258 0.9567018804519443 0.9237939846242145 0.9619753230760634 0.8126303687105643 0.9913473040836458 1.0601946203473114 1.0390693487941438 0.9094760443900981 1.0774654191224344 1.0 16.43926490237262 -6.501983514962183 24.65658829361054 1.014372430821273 0.9159407184200533 0.42635652316354244 0.05693462385959578 648.3339993960735 765041.8595264822 0.017501200390695023 0.01962337547483094 3.147867799236426e-07 6.501983514962183 -0.09843171240121962 EQFEGLGST(ph)PDAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EQFEGLGSTPDAK 13 0 Q8NCN4 Q8NCN4 RNF169 E3 ubiquitin-protein ligase RNF169 1 EQFEGLGS(0.017)T(0.983)PDAK;EQFEGLGS(0.167)T(0.833)PDAK 141.0 0.00018405 7404900.0 50713.0 63174.0 62752.0 73824.0 82071.0 66470.0 73243.0 64186.0 58879.0 49640.0 True False 59297.70927259334 69445.49721757878 64248.24566828529 69687.8806206372 65989.77670160317 62984.19618625265 66304.89280660036 62501.1855106885 59739.99398687567 58639.33904997619 1.011227449580495 1.184281718427844 1.0956509181239038 1.188415179121387 1.1253499403423097 1.0740945789408285 1.1307237407654116 1.0658576055473783 1.0187699069384366 1.0 15.839581221856516 -8.100222483403055 1.7144127742742035 0.9996711513800387 1.1203641144620906 0.43033652345910445 0.04875430277282114 0.330666221754178 1.7337730464040286 0.0420858632634095 0.013279059522982875 7.939214149349987e-09 8.100222483403055 0.12069296308205191 EQFEGLGST(ph)PDAK ddPTM_PC-9_Lapatinib_30min_R1 4 EQFEGLGSTPDAK 13 0 Q8NCN4 Q8NCN4 RNF169 E3 ubiquitin-protein ligase RNF169 1 EQFEGLGS(0.082)T(0.918)PDAK;EQFEGLGS(0.041)T(0.959)PDAK;EQFEGLGS(0.019)T(0.981)PDAK;EQFEGLGS(0.033)T(0.967)PDAK 166.79 0.00018405 20751700.0 206598.0 226897.0 247923.0 227730.0 249707.0 230758.0 218325.0 214469.0 235376.0 209293.0 True False 203651.87463456712 226371.63393701005 227539.72795045562 244478.0238850099 235019.72520285062 220889.0182631712 229628.80022757087 224434.0126975773 208865.47626083766 245469.01618460778 0.829643911072705 0.9222004367621072 0.9269590577546934 0.9959628619733718 0.9574313241476526 0.8998651711589094 0.9354695912207344 0.9143068896678558 0.8508832581288304 1.0 17.90518140929128 -4.749482619352249 3.5907651344683593 0.9334107570318231 0.8135658243313767 0.3634461148994945 0.04156153335512123 0.3755818406578582 7.760786197480793 0.010678324818508871 0.12761362106837768 1.780399159750859e-05 4.749482619352249 -0.11984493270044638 EQFVEFR ddPTM_PC-9_Lapatinib_30min_R1 2 EQFVEFR 7 0 O43852;O43852-3;O43852-2;O43852-4;H0Y875;O43852-15 O43852 CALU Calumenin 0 ; 110.12 0.043826 16614200.0 84076.0 88992.0 84933.0 72650.0 69628.0 82663.0 70724.0 76079.0 84509.0 62433.0 False True 82877.06082234986 88785.94449165228 77950.13659086093 77992.92335329532 65532.61793391491 79127.69618686457 74385.74266481036 79613.90808004433 74990.70650077808 73224.46086325684 1.1318220693644816 1.2125175582713508 1.0645368456372668 1.065121168989463 0.8949552808083343 1.0806183514909278 1.0158592058973592 1.0872583716078084 1.0241209783820684 1.0 16.1600380454244 -5.455678075086807 3.04109908769456 1.0249506229152716 1.1719334746245047 0.5286274324762126 0.05477773332853438 0.19590931887182092 3.5143461442586337 0.014964402119272056 0.03442070938559005 3.5020466337524445e-06 5.455678075086807 0.1469828517092331 EQGHAPGGTSQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EQGHAPGGTSQAR 13 0 F8W930;Q9Y6M1-5;Q9Y6M1-6;Q9Y6M1-3;Q9Y6M1-4;Q9Y6M1-1;Q9Y6M1 F8W930 IGF2BP2 Insulin-like growth factor 2 mRNA-binding protein 2 0 74.133 0.032427 0.0 965.38 2393.0 2701.1 3030.1 3581.0 4122.9 3365.9 2739.1 2350.2 3200.0 False True 1128.799766875873 2630.561225213955 2765.5044679787934 2860.333320716747 2879.3287564235916 3906.6878660493576 3047.0575849942848 2667.201527316346 2384.567228858423 3780.1346688139392 0.2986136383416327 0.6958908757711861 0.7315888745430602 0.756674978887514 0.7617000474025477 1.0334784890812172 0.8060711725781807 0.7055837320613795 0.6308154173794576 1.0 11.884221916613523 -4.635123660274785 1.6917668959054277 0.8018050309713605 1.0119207083413252e-15 0.6213679373000877 0.11816055992971065 1.0208015804414117 2.1644490726744268 0.03360380683824382 1.4983677384620886 2.316734892876614e-05 4.635123660274785 -0.8018050309713595 EQGLTLPLYQS(ph)PVKELDKFK ddPTM_PC-9_Lapatinib_30min_R1 1 EQGLTLPLYQSPVKELDKFK 20 2 P51587 P51587 BRCA2 Breast cancer type 2 susceptibility protein 1 EQGLT(0.001)LPLY(0.195)QS(0.803)PVKELDKFK 40.614000000000004 0.040373 1661100.0 11384.0 8472.3 9500.1 8735.0 9249.3 9090.3 6665.0 9311.1 9015.4 8145.7 True False 11221.662072430081 8452.682909886564 8719.038449446494 9377.401039105793 8705.274358823452 8701.529059524288 7010.081087904542 9743.727697841718 7999.990715629282 9553.673391537015 1.1745913443483038 0.8847573664569957 0.9126372749114628 0.9815492590957348 0.9111965630450476 0.9108045359005482 0.7337576658329478 1.0198933225489013 0.8373732686650099 1.0 13.221839841347329 -4.758447339292754 24.99289442915662 0.9076795636660343 1.1745917081190007 0.5020363989080693 0.07895294561279874 66.7473575559662 557450.1153776952 0.018792340234013098 0.12832632198294233 1.7440248176990344e-05 4.758447339292754 0.2669121444529664 EQGS(ph)LDAER ddPTM_PC-9_Lapatinib_30min_R1 2 EQGSLDAER 9 0 Q96IF1 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 EQGS(1)LDAER;EQGS(1)LDAER 81.33800000000001 0.0098484 7945600.0 14614.5 25405.0 17158.2 18843.7 21022.8 13913.5 28089.6 26345.0 20393.8 20816.1 True False 14406.094550028944 25346.176283378543 15747.519028567358 20229.528558740447 19786.280236415038 13318.45203895264 29543.94204453161 27569.08487715094 18096.83548776543 24414.135149290232 0.5900718768834929 1.0381762912504975 0.6450164600250101 0.8285990240915234 0.8104436268343613 0.5455221721970288 1.21011626518298 1.129226356312377 0.7412441758475128 1.0 14.575429052141681 -7.265827359979625 24.999980417126835 1.0309155545604751 0.7588965352475661 0.37876898573193185 0.17296098626450604 418.99204502206294 2387141.940439193 0.06883496442756044 0.048218492632836146 5.422163885238196e-08 7.265827359979625 -0.27201901931290906 EQGTGNSYTDTSGPKETSSAT(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 1 EQGTGNSYTDTSGPKETSSATPGR 24 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 EQGTGNSYTDTSGPKETSS(0.008)AT(0.991)PGR 59.536 0.032222 0.0 10138.0 4310.0 5649.5 5435.9 4104.9 3907.9 3031.1 2341.2 5847.4 2135.2 True False 9993.430260918496 4300.020459805612 5185.019917700654 5835.674219630815 3863.4578525439097 3740.768226759839 3188.0355267137943 2449.9806989708004 5188.804236148223 2504.2664750248373 3.9905618513778096 1.7170778360409764 2.070474515955507 2.3302928333826523 1.5427502987698591 1.49375805812468 1.273041650522505 0.9783226838695357 2.0719856644236554 1.0 11.290172369992597 -2.211586388046891 0.8378204151984064 1.4915276492613687 199.99999999999986 0.7163990888387259 0.44443020474953066 94.69012056043036 1.0202714385900167 0.1565342539601073 34849.02550485614 0.006143468162446323 2.211586388046891 198.5084723507385 up EQGVLSFWR ddPTM_PC-9_AZD4547_30min_R2 1 EQGVLSFWR 9 0 P12236;P05141 P12236 SLC25A6;SLC25A5 ADP/ATP translocase 3;ADP/ATP translocase 3, N-terminally processed;ADP/ATP translocase 2;ADP/ATP translocase 2, N-terminally processed 0 92.23899999999999 0.033092 3450800.0 15685.0 9343.4 13436.0 16164.0 12104.0 8314.9 17355.0 17978.0 10202.0 12612.0 False True 20672.503731732693 12363.471329854563 13257.82986107355 12437.639531310553 10423.568530248309 7794.9679885558535 18899.561378910108 15199.913193341425 10741.256892204205 12170.45771879404 1.698580629371852 1.0158591907979324 1.089345213417927 1.0219533084695673 0.8564647913078796 0.6404827302853693 1.5529047317361577 1.248918778943638 0.8825680299285036 1.0 13.5710958069451 -4.760068268508678 24.969476610330965 1.0417362102673493 1.6985814366782839 0.4280807384738955 0.23020681660082964 35.91661601202572 653838.9467363468 0.06013405088091618 0.365572003390729 1.737527678267689e-05 4.760068268508678 0.6568452264109346 EQGVLSFWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EQGVLSFWR 9 0 P12236;P05141 P12236 SLC25A6;SLC25A5 ADP/ATP translocase 3;ADP/ATP translocase 3, N-terminally processed;ADP/ATP translocase 2;ADP/ATP translocase 2, N-terminally processed 0 ; 101.46 0.016086000000000003 6502900.0 28629.0 29049.0 26724.0 28018.0 42198.0 32027.0 28771.0 33924.0 27049.0 24476.0 False True 33475.32425147547 31932.792741847115 27361.201511334373 26448.24229558159 33929.60482087758 30347.44773968876 26045.602595998287 33033.53094544912 27444.540453319518 28913.305048090595 1.1577826953991255 1.104432464179875 0.9463187091833792 0.9147429618160586 1.1734945128010628 1.0496014789458625 0.9008172034527859 1.142502764402253 0.9492010826044229 1.0 14.819445910673554 -5.054700859626934 5.618539770794949 1.0148256365873551 1.1465362413506723 0.2471919950284509 0.08665707331586167 0.2598389374945844 18.22050311607445 0.022126282330614793 0.06455939171766205 8.816559451422824e-06 5.054700859626934 0.1317106047633172 EQHNVS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EQHNVSPR 8 0 C9JAN6;P50443 C9JAN6 SLC26A2 Sulfate transporter 1 EQHNVS(1)PR 66.663 0.027451 2475400.0 6667.5 11978.0 9263.7 4077.3 14432.0 7942.0 4737.5 4114.3 6103.4 8261.9 True False 7796.176060872287 13167.096680155759 9484.581740777896 3848.862099784953 11604.153200978846 7525.50753890805 4288.729703470222 4006.303984461187 6192.650678501623 9759.717068835589 0.7988116874583161 1.349126884241399 0.9718090876900267 0.3943620570800166 1.1889845903456413 0.7710784529746519 0.43943176561591674 0.4104938653656249 0.63451129113935 1.0 13.252623609775627 -7.002532458235285 24.818818629722646 0.5767367446137961 0.9392322196644657 0.22038585779775266 0.27875286343401723 127.07464997227525 1245380.7179126928 0.100038264654369 0.08671713745314899 9.941857678707425e-08 7.002532458235285 0.3624954750506696 EQHNVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 EQHNVSPR 8 0 C9JAN6;P50443 C9JAN6 SLC26A2 Sulfate transporter 1 EQHNVS(1)PR;EQHNVS(1)PR 80.737 0.010697 2907030.0 22810.2 40796.3 9993.0 3800.0 14634.6 7107.4 8555.4 9122.099999999999 16519.0 4555.3 True False 22484.922365121638 40701.83867386722 9171.41411409551 4079.4646764283943 13773.821600730626 6803.43307015862 8998.356750106303 9545.946067863297 14658.456267218337 5342.677535444288 4.208549405415655 7.618247293392474 1.7166325411276822 0.7635618375551376 2.5780746656246056 1.2734126334639169 1.6842410365232747 1.7867344612385392 2.7436535650844522 1.0 12.383347228632706 -5.276488204734218 24.999999944003875 1.7044625302545264 5.913398197442428 0.7553110454436122 0.960772031831131 295.3936943405407 490725.3784205897 0.2326099975988368 0.48721771011952664 5.29068366301324e-06 5.276488204734218 4.208935667187902 EQHT(ph)MPLT(ph)HTADITVLRWS(ph)PSGNCLLS(ph) ddPTM_PC-9_AZD4547_30min_R2 1 EQHTMPLTHTADITVLRWSPSGNCLLS 27 1 H3BNC5 H3BNC5 IFT140 4 EQHT(0.947)MPLT(0.81)HT(0.238)ADIT(0.191)VLRWS(0.759)PS(0.076)GNCLLS(0.979) 41.49100000000001 0.021922 6822000.0 15341.0 12257.0 11161.0 23379.0 18181.0 20469.0 12951.0 18515.0 13766.0 16768.0 True False 20219.118887377175 16218.835551301167 11012.997847532151 17989.33275194934 15656.881976903866 19189.070194199536 14103.613910588576 15653.932182373814 14493.642656154003 16180.95742378198 1.2495625788904248 1.0023409076809953 0.6806147225469975 1.111759476327989 0.9676115922468312 1.185904498209505 0.8716180100603796 0.9674292918765381 0.8957221922388817 1.0 13.982009353799215 -4.780169884971924 4.981613738722048 0.9619491455696814 1.2636441306105526 0.30868645061010913 0.12890344803182865 0.19690232734682492 12.295266155274211 0.032011631961800395 0.1988766416661971 1.6589378461428697e-05 4.780169884971924 0.3016949850408712 EQILEEFSK ddPTM_PC-9_Lapatinib_30min_R1 1 EQILEEFSK 9 0 O60506-2;O60506;O60506-4;O60506-3;B7Z645;O60506-5 O60506-2 SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0 104.79 0.012343999999999999 3113700.0 26584.0 28888.0 32190.0 26040.0 39580.0 34606.0 28872.0 29080.0 37567.0 27448.0 False True 26204.907285091474 28821.111610873435 29543.462456993348 27955.068466893525 37251.982217274 33125.98205052609 30366.85088821901 30431.162961759306 33335.808861952355 32192.35022783898 0.8140103813368139 0.8952782697409213 0.9177168565793326 0.8683761287710774 1.1571687669159243 1.029001667044481 0.9432940022489774 0.9452917462187446 1.0355195761111144 1.0 14.974430285295648 -6.155255883222788 24.999883693345964 1.0124793649946697 0.8785078667125682 0.5721044581349427 0.061054821242281655 26.271019780989526 6173.283571258023 0.01911783441894514 0.024681019685893656 6.994297755216836e-07 6.155255883222788 -0.13397149828210153 EQIS(ph)DIDDAVR ddPTM_PC-9_AZD4547_30min_R2 2 EQISDIDDAVR 11 0 P53999 P53999 SUB1 Activated RNA polymerase II transcriptional coactivator p15 1 EQIS(1)DIDDAVR;EQIS(1)DIDDAVR 159.41 0.00018864 26276000.0 55027.0 57501.0 68266.0 73072.0 78068.0 72182.0 57079.0 75871.0 68222.0 61686.0 True False 72524.44136729705 76087.07375665905 67360.74823578795 56226.37935114608 67229.60575177007 67668.44812925452 62158.920423325224 64146.8802921353 71828.07564202661 59526.3919157571 1.2183577575125843 1.2782073851265663 1.1316114763199183 0.9445621940385491 1.1294083781680353 1.1367806102714948 1.0442245602806521 1.0776208372064142 1.206659320855178 1.0 15.861241830223252 -5.407395338663383 4.8196921316611805 1.08065904069186 1.2457559762819677 0.47572285664462766 0.07069564742752031 0.18631037274956175 6.5301404681236015 0.01861978399911432 0.040082694332823826 3.913854363781701e-06 5.407395338663383 0.16509693559010774 EQIS(ph)DIDDAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EQISDIDDAVR 11 0 P53999 P53999 SUB1 Activated RNA polymerase II transcriptional coactivator p15 1 EQIS(1)DIDDAVR;EQIS(1)DIDDAVR 127.3 0.00036733 26555000.0 53457.0 61580.0 55488.0 55447.0 56618.0 54028.0 64252.0 62860.0 55227.0 45765.0 True False 62506.214276122984 67693.2554319578 56811.04435941182 52340.484351599385 45524.10933571371 51194.676569141804 58165.58541580346 61209.9916056754 56034.59039578083 54061.8322244593 1.1561985915794244 1.2521450466366402 1.0508531069301918 0.9681596460565182 0.8420748513794756 0.9469652518728304 1.0759085110971784 1.1322219223265992 1.036490775287283 1.0 15.722322787025972 -5.399995116765974 4.433832174379 1.0006374800225821 1.2024291634169724 0.5242355530684089 0.07638899839992985 0.19489828848982277 6.074563612734216 0.023502423230099902 0.051317257327820234 3.981116469203213e-06 5.399995116765974 0.20179168339439024 EQIS(ph)DIDDAVR ddPTM_PC-9_Lapatinib_30min_R1 1 EQISDIDDAVR 11 0 P53999 P53999 SUB1 Activated RNA polymerase II transcriptional coactivator p15 1 EQIS(1)DIDDAVR 149.3 0.00030583 14616000.0 32497.0 40467.0 45461.0 35635.0 43681.0 50405.0 43264.0 33051.0 42185.0 45481.0 True False 32033.586820780056 40373.30114778507 41723.3720645348 38255.716774875196 41111.76946015019 48249.29564979393 45503.99822762217 34586.67011860756 37433.68107225651 53342.330250376894 0.600528448427761 0.7568717181698265 0.7821812783336364 0.717173707922235 0.7707156636611262 0.9045217076817341 0.8530560628685819 0.6483906862760872 0.7017631381409706 1.0 15.702993229695712 -4.121406504121761 1.2701154245770867 0.7900081690847414 1.172011470990584e-15 0.2651960005031814 0.09737813876934803 9.792374576586166 4.141163603321609 0.028928453924766548 15.216293699306577 7.561248230454272e-05 4.121406504121761 -0.7900081690847401 EQISDIDDAVR ddPTM_PC-9_AZD4547_30min_R2 2 EQISDIDDAVR 11 0 P53999 P53999 SUB1 Activated RNA polymerase II transcriptional coactivator p15 0 ; 191.52 0.0015054 28191000.0 57488.0 62107.0 80676.0 107889.0 91396.0 81065.0 70845.0 95742.0 81008.0 80081.0 False True 75767.98817531722 82181.8731814198 79606.18352723804 83016.85791843376 78707.24300979609 75995.9927350035 77150.06775504962 80947.27383228902 85289.91749889033 77277.38856475949 0.9804677614309215 1.0634659724888385 1.0301355287197236 1.0742710055330678 1.018502882558439 0.983418230693935 0.9983524183195817 1.0474897681674908 1.103685296345337 1.0 16.237758721544978 -7.987716919366495 23.527989892424568 1.0597576079712396 1.0236241741286973 0.10554383748588969 0.03720129674662742 201.88425640362883 386704.5682344339 0.020467099704648318 0.009818284193180574 1.0286865953115097e-08 7.987716919366495 -0.036133433842542306 EQISDIDDAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EQISDIDDAVR 11 0 P53999 P53999 SUB1 Activated RNA polymerase II transcriptional coactivator p15 0 ;;; 161.94 0.0015015999999999999 21195000.0 95873.0 112126.0 116786.0 129951.0 141682.0 116438.0 122834.0 108845.0 109096.0 87106.0 False True 112102.40532193611 123257.1282650816 119570.62115337167 122670.26677682647 113920.42917274724 110331.78630261592 111198.2742788518 105987.93408081033 110691.32261064553 102897.62826928329 1.0894556775260544 1.1978617033088212 1.162034763721231 1.1921583503926654 1.1071239550305014 1.0722480989928886 1.0806689731258499 1.0300328186713856 1.075742215563668 1.0 16.65085020376707 -6.644865196556288 1.9778626409012405 1.0510673437521825 1.163229576143841 0.6768144027626452 0.035366849846083695 0.1893287309570045 1.5173196162455245 0.013149102326386736 0.013086061564252068 2.2653473541392759e-07 6.644865196556288 0.11216223239165846 EQISDIDDAVR ddPTM_PC-9_Lapatinib_30min_R1 4 EQISDIDDAVR 11 0 P53999 P53999 SUB1 Activated RNA polymerase II transcriptional coactivator p15 0 ;;; 194.48 0.00047543 47641400.0 132066.0 167371.0 166678.0 165651.0 178670.0 169930.0 142936.0 150038.0 166955.0 145379.0 False True 130182.71462206182 166983.46273274327 152974.3782356862 177833.52713553657 168160.98187873553 162662.4900261776 150336.52668878052 157009.313220648 148150.76978590921 170507.56644465931 0.7635011004881973 0.9793316872359453 0.8971706149201081 1.0429656046569347 0.9862376514142239 0.953989863429152 0.8817000314034416 0.9208348725779724 0.8688809117101186 1.0 17.379476236149472 -4.755052247071594 24.999097774134377 0.9461322641735593 0.7635007966691817 0.5201386733997453 0.05311055333705417 185.85432791786363 727361.606512551 0.013723042200882505 0.12642341802996895 1.75771214261781e-05 4.755052247071594 -0.18263146750437764 EQISS(ph)EPEDFAQPGDVYSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EQISSEPEDFAQPGDVYSQR 20 0 Q9C0G0-3;Q9C0G0-2;Q9C0G0 Q9C0G0-3 ZNF407 Zinc finger protein 407 1 EQIS(0.001)S(0.999)EPEDFAQPGDVYSQR 226.14 7.437599999999998e-102 0.0 3846.8 3898.1 4712.4 4148.8 3192.1 3902.9 4251.7 5351.6 2688.0 4294.2 True False 4497.987262236746 4285.077606354581 4824.761487876523 3916.3561865910797 2566.6309196815832 3698.2250533372235 3848.948196357649 5211.126170488906 2727.306914803609 5072.704467131502 0.8867039843108098 0.8447323580783516 0.9511221320182318 0.7720450130629608 0.5059689434525553 0.729044058706713 0.7587566398351886 1.0272875552388878 0.5376435651781304 1.0 12.308539396989326 -5.87011503963084 6.919958485145744 0.7491271352955704 0.8884205675338791 0.12613463499151778 0.15831149190261096 0.4434345469832525 25.474412854442047 0.04447798543718635 0.06647361557317538 1.3486056051058607e-06 5.87011503963084 0.1392934322383087 EQISS(ph)EPEDFAQPGDVYSQR ddPTM_PC-9_Lapatinib_30min_R1 1 EQISSEPEDFAQPGDVYSQR 20 0 Q9C0G0-3;Q9C0G0-2;Q9C0G0 Q9C0G0-3 ZNF407 Zinc finger protein 407 1 EQIS(0.228)S(0.772)EPEDFAQPGDVYSQR 250.39 3.2912999999999996e-137 0.0 5283.3 4243.7 6376.4 4153.3 5529.5 4454.2 4115.8 3677.9 5645.7 4283.0 True False 5207.959173161439 4233.873973382152 5852.1570056157925 4458.747537002643 5204.265681415275 4263.704249247335 4328.895985235935 3848.7886608340627 5009.821814143382 5023.310843261232 1.0367582926204761 0.8428453077041592 1.1649999747609603 0.8876113137581463 1.0360230222258282 0.8487836771971002 0.8617615195052375 0.7661856454687073 0.9973147134352743 1.0 12.294422836629035 -6.767064304291102 24.999877463004953 0.8781302303876729 0.9888983541119148 0.17264637631442492 0.10480056796103512 214.61497327785025 953845.8522038531 0.034408326100469344 0.031177800178359617 1.7097621385319343e-07 6.767064304291102 0.11076812372424194 EQIVPKPEEEVAQK ddPTM_PC-9_Lapatinib_30min_R1 2 EQIVPKPEEEVAQK 14 1 A0A087WXM6;J3QQT2;J3KRX5;A0A0A6YYL6;P18621;P18621-3;J3QLC8;A0A0A0MRF8;P18621-2 A0A087WXM6 RPL17;RPL17-C18orf32 60S ribosomal protein L17 0 ; 110.44 0.00064136 14903300.0 81539.0 98964.0 93592.0 84926.0 99773.0 69043.0 92182.0 73760.0 89727.0 86717.0 False True 80376.23890757875 98734.85493832984 85897.22703556746 91171.74134483121 93904.54830126512 66090.19183709398 96954.73291000997 77187.15887411856 79621.00039280222 101705.91790686086 0.7902808465991608 0.9707877080343364 0.8445646900727004 0.8964251365227683 0.9232948311548597 0.6498165809546829 0.9532850684145845 0.7589249520839502 0.7828551379450375 1.0 16.63404410138528 EQIVVDLSHPGVSEDDQVSR ddPTM_PC-9_Lapatinib_30min_R1 3 EQIVVDLSHPGVSEDDQVSR 20 0 O60701;O60701-2;O60701-3 O60701 UGDH UDP-glucose 6-dehydrogenase 0 ;; 160.67 5.6792e-06 26823000.0 98468.2 100634.2 113477.3 97551.8 108944.9 124896.5 104109.2 85903.1 106198.5 105054.9 False True 97064.02541114348 100401.18769284678 104147.63442904565 104726.08479526517 102536.97517591437 119554.96784296184 109499.46496577215 89894.47163068474 94237.30661021775 123213.49948814466 0.7877710300768039 0.8148554185209809 0.8452615570671824 0.849956256662783 0.8321894565276937 0.9703073797888937 0.8886969806121605 0.7295829759249245 0.7648293977664766 1.0 16.910800803340315 -5.018053718395747 1.4467587045216694 0.8557137605555742 0.77597352743178 0.08943737176801925 0.07731385489855173 2.4003592873102666 6.350929758481232 0.023913500746987476 0.24484741016385922 9.592819694612256e-06 5.018053718395747 -0.07974023312379419 EQLAIAEFAR ddPTM_PC-9_Lapatinib_30min_R1 3 EQLAIAEFAR 10 0 P17987;F5H282;E7EQR6 P17987 TCP1 T-complex protein 1 subunit alpha 0 ;; 123.62 0.0020275 6158800.0 27994.7 31482.7 34039.7 27296.4 30129.1 30073.9 32775.9 28434.7 24593.1 27181.6 False True 27595.49044440078 31409.803742441305 31241.08726304185 29303.868314121068 28356.965574089674 28787.70940268497 34472.87572828961 29755.87996797584 21823.16610117605 31879.903342794634 0.8656077199380154 0.9852540456193203 0.9799617937079734 0.9191956449499151 0.8894934614191294 0.9030049148248579 1.0813356413792587 0.9333742216223232 0.6845430447676822 1.0 14.960359634753548 -8.033094215092271 24.912496408772647 0.831167179978862 0.9486849960926071 0.16644760367694778 0.09125604009397398 924.0325333773415 695583.085593832 0.058326591075462925 0.02208169396156989 9.266287803314161e-09 8.033094215092271 0.11751781611374512 EQLDTS(ph)NESAEPK ddPTM_PC-9_AZD4547_30min_R2 2 EQLDTSNESAEPK 13 0 Q96DX7 Q96DX7 TRIM44 Tripartite motif-containing protein 44 1 EQLDT(0.052)S(0.59)NES(0.357)AEPK;EQLDT(0.185)S(0.791)NES(0.025)AEPK 162.64 0.00033188 5582600.0 49549.0 47979.0 41721.0 47053.0 44448.0 49479.0 49677.0 57416.0 47804.0 40264.0 True False 65304.55131677545 63487.27346951772 41167.752279982895 36205.657811603276 38277.16242832753 46385.07030821235 54098.15676289927 48543.67648842429 50330.82184619978 38854.369615407806 1.680751790935729 1.633980272950862 1.0595398326487766 0.9318297573729217 0.9851443430225829 1.1938186301140818 1.3923313464709128 1.2493749601119293 1.2953709542681902 1.0 15.245789234758668 -5.25343472657436 23.549169393767524 1.1455260155076146 1.6573662484123295 0.685456573554444 0.1405477765287286 171.81259162787495 505453.77141747 0.041136738819929804 0.10440437757483709 5.579114486012178e-06 5.25343472657436 0.5118402329047149 EQLDTS(ph)NESAEPK ddPTM_PC-9_Lapatinib_30min_R1 2 EQLDTSNESAEPK 13 0 Q96DX7 Q96DX7 TRIM44 Tripartite motif-containing protein 44 1 EQLDT(0.01)S(0.99)NESAEPK;EQLDT(0.057)S(0.934)NES(0.009)AEPK 172.09 4.819100000000001e-05 9206700.0 78239.0 98349.0 90913.0 89659.0 98897.0 86383.0 87071.0 90000.0 94433.0 80350.0 True False 77123.29751272479 98121.27893304445 83438.48407432855 96252.8219536563 93080.07289898294 82688.60045860829 91579.11033832494 94181.7285611535 83796.96111642521 94238.39044035472 0.8183851310739183 1.0412028311874373 0.8853980175641726 1.021375911705289 0.987708644683348 0.8774407125612304 0.9717813505769405 0.9993987388904199 0.8892019560697179 1.0 16.52402727818781 -1.5229191093839103 0.006679924178597688 1.8289811924726207 0.0003246031478251271 0.05552370908148618 0.0691987133565596 113225.5750584282 58.77974353999041 7287.466771919975 8876.211991936332 0.02999721187607325 1.5229191093839103 -1.8286565893247955 EQLDTSNES(ph)AEPK ddPTM_PC-9_AZD4547_30min_R2 1 EQLDTSNESAEPK 13 0 Q96DX7 Q96DX7 TRIM44 Tripartite motif-containing protein 44 1 EQLDTS(0.024)NES(0.976)AEPK 201.3 1.7309999999999997e-47 0.0 23844.0 22502.0 23990.0 23003.0 23185.0 28004.0 26523.0 29740.0 28038.0 24049.0 True False 31425.89601399006 29775.33144940679 23671.87692521245 17700.01374280726 19966.16295223125 26252.905453044306 28883.49561814075 25144.366357212926 29520.031439288516 23207.051829945904 1.3541528775076344 1.2830294717136501 1.0200294763278266 0.7626997979970693 0.8603489619679878 1.1312469005290924 1.2445999530569445 1.083479562223718 1.272028504766662 1.0 14.502275637239572 -5.192679384907483 4.580712550633165 1.043022582478585 1.3325842021143013 0.35375407491987376 0.14766982407213008 0.2658241186795958 10.820306100625299 0.04313254496526605 0.12241742933371952 6.416831201818709e-06 5.192679384907483 0.28956161963571625 EQLEEEEEAK ddPTM_PC-9_Lapatinib_30min_R1 1 EQLEEEEEAK 10 0 P35579 P35579 MYH9 Myosin-9 0 165.11 1.6787e-14 0.0 9137.1 8399.0 9104.1 11650.0 9578.9 8286.8 11627.0 9629.2 8451.1 10076.0 False True 9006.803278461073 8379.552631533024 8355.59604084229 12506.779863260734 9015.48793484199 7932.3928814743 12228.989168652075 10076.607785122866 7499.248123971721 11817.623174573942 0.7621501502806035 0.7090725865723951 0.7070453946119781 1.058316014862408 0.7628850405586759 0.6712342037222121 1.0348095372479977 0.8526763492343421 0.6345817609167496 1.0 13.528652281472235 -12.195045851111379 2.2598937270376935 7.439979703433189 0.8051280132794435 0.1601768374266077 0.1373355784764249 10004565.717219494 676210.3792747481 332020747.8494174 0.03711899327042729 6.381961043871378e-13 12.195045851111379 -6.634851690153746 EQLEEEEEAKHNLEK ddPTM_PC-9_AZD4547_30min_R2 1 EQLEEEEEAKHNLEK 15 1 P35579 P35579 MYH9 Myosin-9 0 55.815 0.031063 13839000.0 138070.0 130070.0 162760.0 159400.0 148740.0 167500.0 144300.0 160960.0 145220.0 150930.0 False True 181973.38796559366 172112.58384251807 160601.69605450536 122652.79270545051 128090.01843928696 157026.19852110135 157142.42045385932 136087.33049283776 152896.03272749405 145645.98663951692 1.2494226045238677 1.1817186852426471 1.10268535206538 0.842129574150395 0.8794613665278529 1.078136117198692 1.078934092724414 0.9343706176378382 1.0497785504101904 1.0 17.15210642215579 -5.448509176528888 3.4370418559100058 0.9810429747028816 1.2138463987655574 0.5953640160359186 0.07754781659798758 0.17674958418604525 3.993616392874391 0.022811185544709553 0.05097633925395885 3.560334670623782e-06 5.448509176528888 0.23280342406267585 EQLEEEEEAKHNLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EQLEEEEEAKHNLEK 15 1 P35579 P35579 MYH9 Myosin-9 0 ; 106.42 0.0004255 14508700.0 81725.0 70934.0 75453.0 85557.0 97913.0 105691.0 86574.0 84457.0 76625.0 72575.0 False True 95559.4283576735 77975.85873352569 77252.08567709608 80763.51866953634 78727.65052435164 100148.37790162806 78373.08397851832 82240.09323958856 77745.49566474195 85732.2729966162 1.1146260914072017 0.9095274860682085 0.901085238695878 0.9420433618122317 0.9182965500921569 1.1681526034610192 0.9141608082829165 0.9592664508362507 0.9068404808048249 1.0 16.387550773240186 -12.16778788369105 2.0391748701282415 1.659994728442603 0.9680744160056881 0.009189765430522079 0.08905800082658406 12309151.06357977 802553.8589551559 37514828.10176042 0.022208075425451283 6.795354474626098e-13 12.16778788369105 -0.691920312436915 EQLNRPR ddPTM_PC-9_AZD4547_30min_R2 1 EQLNRPR 7 1 C9JJ19;P82930 C9JJ19 MRPS34 28S ribosomal protein S34, mitochondrial 0 75.189 0.042884 426710.0 967.35 2139.4 2697.0 2593.9 727.72 3063.5 973.85 3197.3 1028.9 1213.8 False True 1274.9471778700429 2830.9192117527728 2661.2360178115055 1995.9164303555085 626.688639361558 2871.9388607128 1060.5207634025703 2703.2307516448186 1083.2855534590185 1171.3052314519657 1.0884841488239587 2.4168928266832097 2.272026066606568 1.704010514732649 0.5350344406681308 2.4519132874978333 0.9054179345617149 2.3078790045988757 0.9248533382849858 1.0 10.193901362653842 -8.842601648517569 0.19498233724899197 0.695651902962096 2.0210846647539564 0.10411063019007838 0.6716373955040746 13.425429907917406 1.5547972549978435 5.677470997721437 2.8718933907081925 1.4368067231182862e-09 8.842601648517569 1.3254327617918604 EQLNRPR ddPTM_PC-9_Lapatinib_30min_R1 2 EQLNRPR 7 1 C9JJ19;P82930 C9JJ19 MRPS34 28S ribosomal protein S34, mitochondrial 0 ; 95.352 0.013475999999999998 0.0 3515.8999999999996 2551.0 3527.1800000000003 1034.06 1350.22 1472.74 2402.3999999999996 1580.1999999999998 3493.0 4332.3 False True 3465.762621262907 2545.093316232974 3237.188875708539 1110.1082219230377 1270.8027142346564 1409.7543433246199 2526.7845169665206 1653.621860803716 3099.581557079339 5081.13228257311 0.6820847064244956 0.5008909775803212 0.6370999012978286 0.21847654424003177 0.25010226925072604 0.27744885685414855 0.49728768637508186 0.32544357612479113 0.6100178827679912 1.0 12.310934308515876 -8.602112133044873 3.8279548926819205 0.9998108786398663 0.4193115899781638 0.5750699126596754 0.15088515191963883 0.2740115066795951 10.214364624979781 0.1557785362564681 0.040885003431129975 2.4996998661673025e-09 8.602112133044873 -0.5804992886617024 EQLQLLEEQHR ddPTM_PC-9_AZD4547_30min_R2 1 EQLQLLEEQHR 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 144.28 7.9649e-06 0.0 24258.0 22141.0 26698.0 45050.0 31800.0 25319.0 26256.0 35073.0 25555.0 24658.0 False True 31971.539402255105 29297.645259146553 26343.967075836703 34664.418515561745 27385.118907955726 23735.79892749709 28592.733135388295 29653.273747361418 26905.785128433494 23794.730925311087 1.3436394596186052 1.231266087904439 1.1071344810969863 1.456810695795189 1.1508900434266078 0.9975233173260509 1.2016413728374395 1.2462117701788527 1.1307455088644476 1.0 14.538354519909834 -6.492945778750292 24.996444154181777 1.1291462192912254 1.2726658582824188 0.3448417786315616 0.11001224185881434 930.4762329398188 777023.6720899717 0.03445848140330688 0.03901870505233241 3.214061786124791e-07 6.492945778750292 0.14351963899119347 EQLQLLEEQHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EQLQLLEEQHR 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 88.803 0.0080813 2783700.0 17166.0 24969.0 22301.0 20827.0 21639.0 20918.0 24472.0 20799.0 21951.0 18280.0 False True 20071.864756045554 27447.757305627758 22832.740417013458 19660.13071204503 17398.99328686123 19821.02325596557 22153.83499806298 20253.048288362123 22271.99184778797 21594.019295599617 0.9295103649433042 1.2710814475941958 1.0573640832888513 0.9104433242796689 0.8057320431498716 0.9178941161733914 1.0259245717436882 0.9379008146245958 1.031396311307664 1.0 14.39834417678423 -5.615995570728346 5.056793538645539 0.9413927204085663 1.1147296638607223 0.29445113522188904 0.09884881920934285 0.2172811144073924 9.134312755089807 0.026913766373442494 0.04780606152005026 2.421053738392323e-06 5.615995570728346 0.173336943452156 EQLSAER ddPTM_PC-9_Lapatinib_30min_R1 1 EQLSAER 7 0 Q9UQE7 Q9UQE7 SMC3 Structural maintenance of chromosomes protein 3 0 110.34 0.043677999999999995 59621000.0 43647.0 38692.0 50799.0 38026.0 42899.0 34800.0 36326.0 31822.0 38597.0 30132.0 False True 43024.58577612048 38602.41105122938 46622.502309810705 40822.5588910174 40375.765162679076 33311.68512276217 38206.78253551691 33300.56629192247 34249.7994155715 35340.27605163375 1.2174377391183817 1.0923064379811154 1.3192455611182297 1.1551284667775028 1.142485845432793 0.9425983281537552 1.0811116042131381 0.9422837060827942 0.9691435167493028 1.0 15.109025688730648 -6.622811529376498 3.92313639212415 0.9894574068829798 1.193295343020365 0.7034643507258609 0.06488660799286265 0.12840421968914054 3.7214718999332885 0.021826942888182762 0.021828309139813682 2.3833535480637302e-07 6.622811529376498 0.2038379361373852 EQLVDQGIMPPLKS(ph)PAAFHEQIK ddPTM_PC-9_AZD4547_30min_R2 4 EQLVDQGIMPPLKSPAAFHEQIK 23 1 Q9ULH7-4;Q9ULH7;Q9ULH7-5;I3L2S3;Q9ULH7-2;Q9ULH7-3 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2;Phosphatase and actin regulator 1 EQLVDQGIMPPLKS(1)PAAFHEQIK;EQLVDQGIMPPLKS(1)PAAFHEQIK;EQLVDQGIMPPLKS(1)PAAFHEQIK;EQLVDQGIMPPLKS(1)PAAFHEQIK 101.71 2.1508000000000002e-06 62383900.0 279792.0 255087.0 313835.0 418338.0 357380.0 319014.0 264727.0 280185.0 244858.0 280528.0 True False 368760.03596486786 337538.8842518368 309673.342843854 321896.63735767116 307763.9558278375 299066.00414931716 288287.19015584775 236888.8462607839 257800.69399248567 270706.80010607745 1.3622119422946446 1.2468799606052414 1.143943715941038 1.1890969758851082 1.1368903762566698 1.1047598509979322 1.0649425505487167 0.8750753441286223 0.9523244111025859 1.0 18.046371602684538 -6.1976034172379615 0.44505571714741904 0.927572587462817 1.367037995317365 0.8210358282844229 0.05748236888487441 0.7083691575985651 0.2511322022517908 0.05560189762437187 0.14464012876174215 6.344488036075972e-07 6.1976034172379615 0.439465407854548 EQLVDQGIMPPLKS(ph)PAAFHEQIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EQLVDQGIMPPLKSPAAFHEQIK 23 1 Q9ULH7-4;Q9ULH7;Q9ULH7-5;I3L2S3;Q9ULH7-2;Q9ULH7-3 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2;Phosphatase and actin regulator 1 EQLVDQGIMPPLKS(1)PAAFHEQIK 55.302 0.0045206000000000005 21598000.0 24779.0 15701.0 16400.0 31394.0 105690.0 109000.0 148110.0 149690.0 139540.0 128740.0 True False 28973.595292441598 17259.691515705937 16791.03819734636 29635.09596072127 84980.80320201337 103283.84811646657 134079.94857645934 145760.7961096653 141580.50851625556 152079.5428947204 0.19051605982600206 0.1134912111595065 0.11040957828871327 0.19486576167076372 0.558791811077725 0.6791435991359241 0.8816435532639549 0.9584510403912159 0.9309635327761804 1.0 17.214466575235868 -6.6295662207011485 1.122389087643351 0.9606414783345902 0.11145927673264985 0.9825045607541028 0.04730283581433395 0.05746046631552838 0.15407235188296808 0.024263223511327356 0.024956216762059263 2.3465714330118326e-07 6.6295662207011485 -0.8491822016019404 down EQLVDQGIMPPLKS(ph)PAAFHEQIK ddPTM_PC-9_Lapatinib_30min_R1 2 EQLVDQGIMPPLKSPAAFHEQIK 23 1 Q9ULH7-4;Q9ULH7;Q9ULH7-5;I3L2S3;Q9ULH7-2;Q9ULH7-3 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2;Phosphatase and actin regulator 1 EQLVDQGIMPPLKS(1)PAAFHEQIK;EQLVDQGIMPPLKS(1)PAAFHEQIK 56.48 0.0035999 10867800.0 12015.7 5503.700000000001 10961.5 6435.299999999999 33106.0 52015.0 58774.0 53992.0 62351.0 54283.0 True False 11844.35391459049 5490.956520796319 10060.287782613632 6908.573429531486 31158.77016890027 49790.43970288722 61817.030136609326 56500.665427486536 55328.37379486229 63665.74422244912 0.18603966794460347 0.08624663997660705 0.15801728080744376 0.10851319675762874 0.48941185796919356 0.7820601221422723 0.970962185262763 0.8874578647831763 0.869044640419879 1.0 15.958229709117951 -6.599926494026206 1.882653245357183 0.9222484344177204 0.12536825801566367 0.9804246763900717 0.05138503304190249 0.040698983523660075 0.29441226529085823 0.019298360081550708 0.01984266893383291 2.51231161371239e-07 6.599926494026206 -0.7968801764020568 down EQMIDLQNLLTTQS(ph)PSVK ddPTM_PC-9_Lapatinib_30min_R1 2 EQMIDLQNLLTTQSPSVK 18 0 Q9BVJ6-3;Q9BVJ6;Q9BVJ6-2 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 1 EQMIDLQNLLTTQS(0.968)PS(0.032)VK;EQMIDLQNLLTT(0.093)QS(0.906)PSVK 269.99 1.4711999999999997e-78 9650200.0 60215.0 53496.0 60788.0 51565.0 53227.0 54411.0 51020.0 44617.0 49892.0 44221.0 True False 59356.323057921414 53372.13329878447 55790.24528846574 55357.26211579742 50096.29250830831 52083.968368236034 53661.56595722274 46690.06870236643 44272.637573948625 51864.54092922131 1.1444490203610211 1.0290678822670107 1.0756914895786271 1.0673431428100861 0.9659064094806874 1.0042307795477101 1.0346484321620393 0.9002310223102833 0.853620542681883 1.0 15.662460904469361 -6.568241137344538 0.6051045522203641 0.9221441385631449 1.1005121736759813 0.5567394408243782 0.053747313809704544 0.6843758359267641 0.5496267911284126 0.042682945785853146 0.05878360353536297 2.7024574370068656e-07 6.568241137344538 0.1783680351128364 EQMMNSSISSGSGS(ph)LR ddPTM_PC-9_AZD4547_30min_R2 3 EQMMNSSISSGSGSLR 16 0 Q12959-3;Q12959;Q12959-5;A0A590UK48;Q12959-8;A0A590UJX2;A0A590UJS9;A0A590UJ68;A0A590UJ18;Q12959-9;Q12959-6;A0A590UJ08;A0A590UJR5;A0A590UJC5;A0A590UKA8;A0A0C4DFT3;A0A590UJD9;A0A590UJR4;A0A590UJ81;C9JUA9;Q12959-7;Q12959-2;Q12959-4;A0A590UK81;A0A590UJ29;A0A590UJ64;A0A590UJ25;A0A590UK02;A0A590UK70;A0A590UJL2;E7EQD7 Q12959-3 DLG1 Disks large homolog 1 1 EQMMNSSIS(0.01)S(0.299)GS(0.172)GS(0.52)LR;EQMMNSSIS(0.14)S(0.14)GS(0.209)GS(0.509)LR;EQMMNSSISSGS(0.186)GS(0.814)LR 119.08 6.868899999999999e-05 38909800.0 42722.0 41155.0 70743.0 107871.0 106413.0 88729.0 72992.0 102026.0 72865.0 86067.0 True False 56306.70732719691 54457.54892011095 69804.90159734499 83003.00754033649 91639.39177208458 83180.76160345564 79488.14659575954 86260.22602424386 76716.49514315418 83053.82052675575 0.6779544513434843 0.6556898716365188 0.8404779112462065 0.9993881920651333 1.103373585837186 1.0015284194742011 0.95706791200716 1.0386063576263198 0.9236961605931181 1.0 16.34175891412154 -5.514884181254219 2.5307096656179473 1.007833504967858 0.664534841334583 0.8970692400593993 0.04573345089422568 0.0825081300855212 1.0466626125196257 0.013502585480474708 0.03125844375774856 3.0557359159108117e-06 5.514884181254219 -0.343298663633275 EQMMNSSISSGSGS(ph)LR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EQMMNSSISSGSGSLR 16 0 Q12959-3;Q12959;Q12959-5;A0A590UK48;Q12959-8;A0A590UJX2;A0A590UJS9;A0A590UJ68;A0A590UJ18;Q12959-9;Q12959-6;A0A590UJ08;A0A590UJR5;A0A590UJC5;A0A590UKA8;A0A0C4DFT3;A0A590UJD9;A0A590UJR4;A0A590UJ81;C9JUA9;Q12959-7;Q12959-2;Q12959-4;A0A590UK81;A0A590UJ29;A0A590UJ64;A0A590UJ25;A0A590UK02;A0A590UK70;A0A590UJL2;E7EQD7 Q12959-3 DLG1 Disks large homolog 1 1 EQMMNSSIS(0.009)S(0.026)GS(0.026)GS(0.939)LR;EQMMNS(0.001)S(0.001)IS(0.002)S(0.035)GS(0.114)GS(0.847)LR;EQMMNSSISSGS(0.008)GS(0.992)LR;EQMMNS(0.002)S(0.002)IS(0.016)S(0.021)GS(0.23)GS(0.731)LR 111.58 0.00026502 47888400.0 71630.0 69346.4 123077.0 107048.0 140961.0 106902.0 92914.0 95524.0 95305.0 76942.0 True False 83755.5442430117 76230.6522976083 126011.62245212197 101050.44761429845 113340.70394700533 101295.87092978456 84112.51328089322 93016.59621604424 96698.65532565411 90890.975527463 0.9214946121653704 0.8387043032074727 1.3864041146092347 1.1117764665620267 1.246996231355874 1.1144766610979733 0.9254220542002914 1.0233864877810557 1.0638972105259923 1.0 16.471849437356028 -7.227076249210768 22.944729175523452 1.005125304692826 1.1110654296015918 0.09941294860086258 0.1464871619691085 583.4534509721342 389579.4835437889 0.0596587828739958 0.046207235076112844 5.928212336431236e-08 7.227076249210768 0.10594012490876592 EQMMNSSISSGSGS(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 5 EQMMNSSISSGSGSLR 16 0 Q12959-3;Q12959;Q12959-5;A0A590UK48;Q12959-8;A0A590UJX2;A0A590UJS9;A0A590UJ68;A0A590UJ18;Q12959-9;Q12959-6;A0A590UJ08;A0A590UJR5;A0A590UJC5;A0A590UKA8;A0A0C4DFT3;A0A590UJD9;A0A590UJR4;A0A590UJ81;C9JUA9;Q12959-7;Q12959-2;Q12959-4;A0A590UK81;A0A590UJ29;A0A590UJ64;A0A590UJ25;A0A590UK02;A0A590UK70;A0A590UJL2;E7EQD7 Q12959-3 DLG1 Disks large homolog 1 1 EQMMNSSIS(0.002)S(0.079)GS(0.232)GS(0.688)LR;EQMMNSSIS(0.004)S(0.092)GS(0.031)GS(0.873)LR;EQMMNSSISSGS(0.001)GS(0.999)LR;EQMMNS(0.001)S(0.001)IS(0.025)S(0.11)GS(0.186)GS(0.677)LR;EQMMNSSISSGS(0.026)GS(0.974)LR 182.09 1.6443999999999999e-06 34933400.0 270894.0 229916.0 273373.0 215769.0 223213.0 209188.0 156356.0 170787.0 230734.0 170105.0 True False 267031.0018841251 229383.64362799717 250897.32719029603 231637.37204428343 210084.05019364282 200241.51688104533 164451.34862421622 178722.3875085966 204746.30718326516 199507.42259933532 1.338451464136226 1.1497499222806429 1.2575839230511512 1.161046386276433 1.0530137047359296 1.0036795336842392 0.82428686853661 0.8958182366353323 1.0262590961061682 1.0 17.606082896814485 -6.382442459425562 1.4098887331228622 0.9292993837261578 1.2436761576523676 0.7853429107242464 0.06935876670850603 0.18295484279936292 0.7369493302607173 0.02757095891126385 0.03456677510933989 4.1453150253613945e-07 6.382442459425562 0.3143767739262098 EQMMNSSMSSGS(ph)GSLR ddPTM_PC-9_AZD4547_30min_R2 1 EQMMNSSMSSGSGSLR 16 0 Q92796-2;Q5JUW8;Q92796 Q92796-2 DLG3 Disks large homolog 3 1 EQMMNSSMS(0.012)S(0.008)GS(0.899)GS(0.081)LR 69.805 0.024588 0.0 0.0 1248.2 1263.2 2670.7 2729.1 1167.4 2450.9 3579.8 2584.8 2594.9 True False 0.0 1651.6562401186352 1246.4491426397817 2055.011376903679 2350.2115726950315 1094.4022934539323 2669.025351977571 3026.6241656204065 2721.4272510262144 2504.0533408260885 0.0 0.6595930738335442 0.4977726002548242 0.8206739622510316 0.9385629029450688 0.4370523085953466 1.065881987600575 1.2086899732822471 1.0868088177899653 1.0 11.290049579251162 -5.468887795015651 0.44665781394998305 1.0960443113378078 1.235739171385609e-12 0.6346241792486069 0.2140750082760338 2.0626791710909984 0.5008591828293169 0.1777908336791813 1.1289482862645581 3.3971303002961764e-06 5.468887795015651 -1.096044311336572 EQMQPTHPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EQMQPTHPIR 10 0 Q04917;A2IDB2 Q04917 YWHAH 14-3-3 protein eta 0 ; 94.363 0.004296100000000001 2265100.0 13803.4 15834.4 15373.1 18973.7 21669.2 17928.0 17614.7 20077.5 19639.8 15104.900000000001 False True 16140.042990422871 17406.334586096047 15739.653006806408 17910.66510256537 17423.275813653752 16987.824119559747 15946.108096615724 19550.486898869676 19926.994920148776 17843.298799677403 0.9045436705187425 0.9755110185349104 0.8821044350325496 1.0037754399365428 0.9764604633515837 0.9520562486947133 0.8936748902565047 1.0956767085704544 1.1167775165267673 1.0 14.123094739313311 -7.770559198016268 24.99987698548574 1.0796703821762779 0.9443956181886284 0.6183120900964788 0.046478447555908645 122.9849225367481 337128.9381969492 0.024244246019399684 0.011905855180026459 1.696058399377886e-08 7.770559198016268 -0.13527476398764948 EQMQPTHPIR ddPTM_PC-9_Lapatinib_30min_R1 1 EQMQPTHPIR 10 0 Q04917;A2IDB2 Q04917 YWHAH 14-3-3 protein eta 0 117.25 0.00065988 919710.0 6914.4 5995.3 4335.0 3694.0 6536.6 5901.2 4468.3 4342.3 5854.3 5648.0 False True 6815.799388054335 5981.418251200135 3978.5930335839157 3965.6690828227615 6152.130039450054 5648.819432369086 4699.646710440185 4544.059110345512 5194.9270854880015 6624.249274513062 1.0289165014182462 0.9029579056171342 0.6006104040938851 0.5986593979910684 0.9287286429755147 0.8527486207536056 0.7094610295723887 0.6859734472597332 0.7842288039303702 1.0 12.693541248009174 -5.0211098492305855 6.503422925344665 0.7583447560667784 1.0012111846352978 0.30189020023669944 0.12484034007514755 0.1636195631967705 29.914526333157337 0.03219778863279494 0.09882247171475096 9.525551969050278e-06 5.0211098492305855 0.24286642856851937 EQNSALPTS(ph)SQDEELMEVVEK ddPTM_PC-9_AZD4547_30min_R2 2 EQNSALPTSSQDEELMEVVEK 21 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 EQNS(0.112)ALPT(0.064)S(0.412)S(0.412)QDEELMEVVEK;EQNS(0.005)ALPT(0.141)S(0.427)S(0.427)QDEELMEVVEK 67.778 0.0040814 3009600.0 21385.1 20072.8 22558.2 25347.7 24123.4 28241.6 20815.6 29166.1 25383.3 24909.2 True False 28185.116962287317 26560.940055001898 22259.06352873396 19504.179383061135 20774.282310194325 26475.648287483797 22668.148074839588 24659.14941530289 26725.009416965997 24037.136489770397 1.172565499816594 1.104996015906702 0.9260280873392245 0.8114185893715595 0.8642577837437225 1.1014476827866402 0.9430469425709915 1.0258771641038527 1.1118216776087073 1.0 14.552977419605687 -9.940801387200631 15.390235241541603 0.9999999965857151 0.9988661939872551 0.0 0.11274914224531254 0.0 0.0 0.11824680047810496 0.028679061662503752 1.1460369305197665e-10 9.940801387200631 -0.0011338025984600764 EQNSALPTS(ph)SQDEELMEVVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EQNSALPTSSQDEELMEVVEK 21 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 EQNS(0.005)ALPT(0.059)S(0.492)S(0.444)QDEELMEVVEK;EQNS(0.001)ALPT(0.04)S(0.553)S(0.406)QDEELMEVVEK 75.868 0.00096775 2403000.0 19822.7 27677.0 26715.7 25537.9 29458.6 19804.2 28257.9 19616.7 20666.7 18015.2 True False 23178.29159382874 30424.58964907922 27352.703607856456 24107.094257988916 23686.398800329505 18765.6328886984 25581.10714252057 19101.78241061171 20968.911389944846 21281.21315175528 1.089143341056052 1.4296454545200488 1.285298136567952 1.132787594677165 1.113019198267644 0.8817933806161142 1.2020511687986468 0.8975889802145133 0.9853250019355839 1.0 14.377292774661779 -6.1278471146955 1.7833040075138145 1.0021879954323056 1.2829583504361843 0.497930075400441 0.1156694737545858 0.27960676254753847 1.7631609107976487 0.03819037335518361 0.05627021040772966 7.44994189113864e-07 6.1278471146955 0.2807703550038787 EQNSALPTS(ph)SQDEELMEVVEK ddPTM_PC-9_Lapatinib_30min_R1 1 EQNSALPTSSQDEELMEVVEK 21 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 EQNSALPT(0.032)S(0.484)S(0.484)QDEELMEVVEK 90.166 0.00029361 2531000.0 27447.0 34251.0 34509.0 27995.0 38173.0 35064.0 28128.0 33187.0 33633.0 28684.0 True False 27055.600746836633 34171.69391387518 31671.80322859222 30053.845688582343 35927.73919100555 33564.39445817622 29584.330208638996 34728.989175099945 29844.89736880889 33641.991180972494 0.804221147354053 1.0157452848154325 0.9414366426237402 0.8933432485286553 1.0679433032883574 0.9976934563005248 0.8793870151589462 1.032310750819715 0.8871323105776452 1.0 15.03797547699447 -4.750821956918892 24.98020967294205 0.9674090757782811 0.8042208016152725 0.383294634809322 0.06244007136278592 476.8499284546884 1121837.2642330287 0.014975255937986902 0.21123908783421932 1.774916975558147e-05 4.750821956918892 -0.16318827416300852 EQNSALPTSS(ph)QDEELMEVVEK ddPTM_PC-9_AZD4547_30min_R2 1 EQNSALPTSSQDEELMEVVEK 21 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 EQNS(0.001)ALPT(0.082)S(0.235)S(0.682)QDEELMEVVEK 79.34100000000001 0.00069145 2592000.0 30919.0 30574.0 36861.0 39941.0 37552.0 43468.0 32608.0 48340.0 38651.0 37990.0 True False 40750.59884484812 40456.44759284342 36372.19905545047 30733.21953229858 32338.552994702954 40749.93908844912 35510.048829933774 40870.16374269245 40694.01295241961 36659.98166325605 1.1115826303233551 1.1035588605706406 0.9921499522163149 0.8383315576805701 0.8821213630642805 1.1115646336859029 0.9686324765820917 1.1148440857965902 1.11003909729739 1.0 15.16191844381415 -7.761032727510067 24.999999578780233 1.0843312003562982 0.9981365665407271 0.11513613656997967 0.09244294985974333 23.29732377406712 1432607.2944909504 0.05118671544760789 0.027179703262013383 1.73367334688891e-08 7.761032727510067 -0.08619463381557102 EQNSALPTSS(ph)QDEELMEVVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EQNSALPTSSQDEELMEVVEK 21 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 EQNSALPT(0.015)S(0.202)S(0.783)QDEELMEVVEK 88.43299999999999 0.00030269 2627000.0 32179.0 38365.0 34132.0 34224.0 35248.0 25797.0 34516.0 26764.0 27661.0 24297.0 True False 37626.26913577942 42173.62365454799 34945.836326330835 32306.54023570507 28341.40742988515 24444.159906976955 31246.394605800167 26061.473358802043 28065.48979552926 28701.853765053842 1.3109351557491233 1.4693693306282818 1.2175463164291989 1.1255907196851564 0.9874417053992673 0.8516578792112419 1.0886542333319407 0.9080066246638531 0.9778284714731774 1.0 14.808856298725049 -5.773329114729781 1.605556693561773 0.9638894577333136 1.3923625581978656 0.8382856402594306 0.07319141810157345 0.134422863711849 0.703260078484828 0.022692409861916736 0.049178152905546765 1.6852754149203461e-06 5.773329114729781 0.428473100464552 EQNSALPTSS(ph)QDEELMEVVEK ddPTM_PC-9_Lapatinib_30min_R1 2 EQNSALPTSSQDEELMEVVEK 21 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 EQNSALPT(0.075)S(0.227)S(0.698)QDEELMEVVEK;EQNS(0.001)ALPT(0.022)S(0.135)S(0.842)QDEELMEVVEK 92.363 0.00023057 1254400.0 21961.8 25705.0 24363.4 26154.0 26182.9 26734.7 21591.9 27323.5 25968.3 20093.7 True False 21648.620704699137 25645.481651810493 22360.335297443682 28077.45240718637 24642.87329956197 25591.31920262961 22709.822932021892 28593.049559340827 23043.476595678043 23566.86927182774 0.9186040137532517 1.0882006157036548 0.9488038075627477 1.1913950929727717 1.0456574870137927 1.0859023702915827 0.9636334241124519 1.2132731433072221 0.9777911664840704 1.0 14.524472496813662 -4.10134881366574 1.9122936397810886 1.0637062310245156 9.35196113151223e-14 0.17373541916335178 0.08702195691333892 17.57436467641316 9.59987954097581 0.021636502728182 62.96297521868939 7.918650702406688e-05 4.10134881366574 -1.063706231024422 EQPGEEY(ph)SEEEESVLK ddPTM_PC-9_AZD4547_30min_R2 1 EQPGEEYSEEEESVLK 16 0 Q96PY6-4;Q96PY6-2;Q96PY6-6;Q96PY6;Q96PY6-3 Q96PY6-4 NEK1 Serine/threonine-protein kinase Nek1 1 EQPGEEY(0.521)S(0.463)EEEES(0.016)VLK 91.914 0.0045706 4940800.0 8854.5 9598.9 13307.0 12700.0 12623.0 11780.0 9276.5 9816.5 12928.0 13458.0 True False 11670.046814958696 12701.556708279746 13130.540485360656 9772.211213044046 10870.51433884041 11043.39473778253 10102.090529038289 8299.585485729012 13611.347686964915 12986.839516296384 0.8986056076472396 0.9780329303631838 1.011065122417502 0.7524703143348695 0.8370407846496964 0.8503527531794671 0.7778713609544338 0.6390766187042177 1.0480877714616303 1.0 13.664762758069193 -5.754733139407862 24.999986975693552 0.825793344973125 0.9641144024933773 0.17506042658599985 0.11389376314657014 226.83890999792902 845615.5578252343 0.02982298056381175 0.05019011989658174 1.7590041358527056e-06 5.754733139407862 0.13832105752025237 EQPGEEYS(ph)EEEESVLK ddPTM_PC-9_AZD4547_30min_R2 1 EQPGEEYSEEEESVLK 16 0 Q96PY6-4;Q96PY6-2;Q96PY6-6;Q96PY6;Q96PY6-3 Q96PY6-4 NEK1 Serine/threonine-protein kinase Nek1 1 EQPGEEYS(0.998)EEEES(0.002)VLK 177.64 5.2981e-29 0.0 2483.5 4017.1 4594.4 5406.6 5940.3 5432.8 3515.5 4518.3 4629.5 4402.5 True False 3273.2013399909533 5315.549016327968 4533.475254072367 4160.191901137315 5115.591882041804 5093.086157166801 3828.3726895740974 3820.100555204947 4874.20591868843 4248.3698150167065 0.7704605489901499 1.2511973410457595 1.0671093740587032 0.9792442942307636 1.2041305500193813 1.1988330533665588 0.9011392266374632 0.8991920952130964 1.1473120587241679 1.0 12.052693640980335 -10.769021834152214 5.445495181541442 0.9999959440526976 1.0516676929832325 0.0075562377724399665 0.14977689085975135 7.271821436812216e-06 1.0064033475577305e-06 0.14298296136757246 0.03467574027112301 1.702072934538294e-11 10.769021834152214 0.05167174893053483 EQPGEEYSEEEES(ph)VLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EQPGEEYSEEEESVLK 16 0 Q96PY6-4;Q96PY6-2;Q96PY6-6;Q96PY6;Q96PY6-3 Q96PY6-4 NEK1 Serine/threonine-protein kinase Nek1 1 EQPGEEYS(0.306)EEEES(0.694)VLK 174.59 3.2368999999999997e-22 0.0 10573.0 12793.0 10668.0 11822.0 14235.0 11223.0 12377.0 13787.0 12413.0 11494.0 True False 12362.800073731183 14063.00449400841 10922.36557861529 11159.651667441129 11445.75393680252 10634.446123037655 11204.560958279882 13425.105858533989 12594.516641911157 13577.771213546062 0.9105176305664404 1.0357373292590353 0.8044299323381169 0.8219060029754764 0.8429773750631101 0.7832247248670713 0.8252135628196098 0.9887562286467336 0.9275835071772349 1.0 13.728959060674207 -7.766162127326545 24.99082444216051 0.9686274246514738 0.8600113453841273 0.3500303119442483 0.06960105365980325 155.16595829592652 821052.483372065 0.04019134917296646 0.020302297021292968 1.7133175861528177e-08 7.766162127326545 -0.10861607926734651 EQPPAETPTDAAVLT(ph)SPPAPAPPVTPSKPMAGTTDREEATR ddPTM_PC-9_AZD4547_30min_R2 1 EQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATR 41 2 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 EQPPAETPT(0.002)DAAVLT(0.434)S(0.366)PPAPAPPVT(0.091)PS(0.033)KPMAGT(0.033)T(0.033)DREEAT(0.007)R 41.513999999999996 0.012765 31365000.0 28488.0 25203.0 31360.0 38710.0 35515.0 34177.0 25218.0 30051.0 25861.0 30219.0 True False 37546.59141278932 33349.376878473005 30944.145909740015 29786.00756353818 30584.3552835235 32039.90678719809 27462.353146260743 25407.308453281978 27227.959663722115 29161.042007947737 1.287560005659473 1.1436277506607533 1.061146782796935 1.0214315234489943 1.0488087248455609 1.0987229735640356 0.9417480053962398 0.871275739953233 0.9337101073514874 1.0 14.831754651780823 -1.522878745280338 0.3560517607798272 0.940993521317161 5.048122856754974 0.770306124835547 0.05408574074512052 32.32592275784345 0.4528174566951366 0.05024636312831206 89.64545668703315 0.029999999999999964 1.522878745280338 4.107129335437813 EQPPAETPTDAAVLTS(ph)PPAPAPPVTPSKPMAGTTDREEATR ddPTM_PC-9_AZD4547_30min_R2 1 EQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATR 41 2 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 EQPPAETPTDAAVLT(0.271)S(0.598)PPAPAPPVT(0.032)PS(0.016)KPMAGT(0.039)T(0.039)DREEAT(0.003)R 52.095 0.0022563 35383000.0 37587.0 33351.0 44968.0 51028.0 42590.0 42920.0 33703.0 48747.0 30382.0 35955.0 True False 49538.88414183211 44131.05853564866 44371.69493843073 39264.282974741036 36677.11365691305 40236.205615078594 36702.50170863771 41214.27124462202 31987.930493917687 34696.22639385028 1.4277888200145192 1.27192675176545 1.2788622726503587 1.1316585996712432 1.0570922970289895 1.1596709439909074 1.0578240207454674 1.187860338953951 0.9219426381073931 1.0 15.082491141519418 -1.5228787452803527 0.300663059681406 1.0197347359091637 4.515187160838349 0.7635084369432791 0.06914023530147226 25.87184212461848 0.3687611856207302 0.06818985577104462 48.67537019340823 0.029999999999998955 1.5228787452803527 3.4954524249291854 EQPPAETPTDAAVLTS(ph)PPAPAPPVTPSKPMAGTTDREEATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATR 41 2 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 EQPPAETPT(0.001)DAAVLT(0.257)S(0.571)PPAPAPPVT(0.058)PS(0.058)KPMAGT(0.023)T(0.023)DREEAT(0.011)R 42.799 0.039833999999999994 19448000.0 21730.0 29165.0 25625.0 28111.0 28844.0 24286.0 33220.0 24213.0 19431.0 15768.0 True False 25408.459812936613 32060.30845522982 26235.997183353662 26536.03180709164 23192.225258386497 23012.399406940414 30073.16110802762 23577.43440579413 19715.141615159588 18626.61358058068 1.3640944288137484 1.7212097258867571 1.4085221164788753 1.4246299625154077 1.2451122775513919 1.2354580346763713 1.6145264933922625 1.2657928562159557 1.0584393953237834 1.0 14.185077787882284 -8.1380229525881 0.1778088548889384 0.8165211319842265 1.6820287567995766 0.48477858799520945 0.15278164281710138 3.293658956204065 0.5837883046911918 1.2165556890830422 1.0690292487220714 7.277413421815143e-09 8.1380229525881 0.8655076248153502 EQPPAETPTDAAVLTSPPAPAPPVT(ph)PSKPMAGTTDREEATR ddPTM_PC-9_Lapatinib_30min_R1 1 EQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATR 41 2 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 EQPPAETPTDAAVLT(0.001)S(0.001)PPAPAPPVT(0.337)PS(0.266)KPMAGT(0.164)T(0.164)DREEAT(0.065)R 49.297 0.0009743 11370000.0 21088.0 25482.0 29795.0 22427.0 25654.0 32063.0 15630.0 19661.0 29104.0 23120.0 True False 20787.281252934423 25422.997994609417 27345.370112025998 24076.35639427885 24145.08215770458 30691.74023250356 16439.24492182265 20574.521836009284 25826.00104129318 27116.261194536477 0.7665983560123971 0.9375554325952493 1.0084491337447246 0.8878936598799939 0.8904281451076099 1.1318573756284471 0.6062504267784127 0.7587521630804598 0.9524174758464392 1.0 14.726870652126035 -7.259471290829403 24.999417403603907 0.8092510405548096 0.9360305674042707 0.12894958632372922 0.13316911764561282 324.32075893134953 4119682.483567721 0.05204256225659376 0.038255107310145975 5.502102911294534e-08 7.259471290829403 0.12677952684946114 EQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEAT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 EQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATR 41 2 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 EQPPAETPTDAAVLTS(0.002)PPAPAPPVT(0.151)PS(0.151)KPMAGT(0.217)T(0.217)DREEAT(0.262)R 46.983000000000004 0.0014204 16892000.0 39500.0 31046.0 48768.0 56769.0 60007.0 51451.0 44997.0 62407.0 47917.0 54800.0 True False 52060.1783489602 41081.01236238035 48121.30445555485 43681.78412230688 51676.06384621698 48233.760836472735 49001.64582926059 52763.43212019457 50449.79479550571 52881.46867982181 0.9844692223691021 0.7768508210524757 0.9099842658855026 0.8260319770387677 0.9772055341181404 0.9121108403495889 0.9266317114970436 0.9977679031506876 0.9540165213822066 1.0 15.690474624997016 -7.017182200929174 0.720063073166628 0.9873170900816004 0.8708384115491296 0.3115107604338425 0.05875359133240334 0.788903093409935 0.8543898827087236 0.04412787184106838 0.034641009547632835 9.612089347756607e-08 7.017182200929174 -0.11647867853247085 EQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEAT(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATR 41 2 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 EQPPAETPTDAAVLTS(0.001)PPAPAPPVT(0.236)PS(0.056)KPMAGT(0.056)T(0.236)DREEAT(0.417)R 69.755 2.1538000000000001e-07 11743000.0 5875.3 5696.9 4791.3 7352.8 7272.5 7900.9 8329.1 7472.4 4907.1 4992.9 True False 6869.872247535497 6262.450582499529 4905.542763106435 6940.846454099231 5847.50583107807 7486.562895260462 7540.107350538014 7276.25741766225 4978.857054178868 5898.073246225347 1.1647655023497856 1.0617790456412823 0.8317195392997005 1.1767989586330143 0.9914264518197294 1.2693234862845622 1.2784017823724954 1.2336668457481288 0.8441497496432822 1.0 12.526028023526626 EQPWHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EQPWHK 6 0 Q14192 Q14192 FHL2 Four and a half LIM domains protein 2 0 ; 81.635 0.021330000000000002 1985400.0 42399.0 46273.0 52988.0 53877.0 57511.0 49149.0 50262.0 50651.0 47720.0 43204.0 False True 49576.313281578434 50866.67763239668 54251.434878109074 50858.44636159075 46242.13239616788 46571.53991813039 45500.8194946323 49321.46491917062 48417.814722629584 51036.5431973242 0.9713885419296516 0.9966716874951588 1.0629919559472325 0.9965104055922269 0.9060592567443383 0.9125136030093058 0.891534117401154 0.9663950931879826 0.9486891487816926 1.0 15.639242995467137 -6.145000180518949 5.541303203959321 0.9325425484155143 1.011940950401424 0.463444160827451 0.03644695068838381 0.19460903224057544 8.143195003093837 0.011075851152451407 0.014433492476191877 7.16143112540622e-07 6.145000180518949 0.07939840198590975 EQPWHK ddPTM_PC-9_Lapatinib_30min_R1 1 EQPWHK 6 0 Q14192 Q14192 FHL2 Four and a half LIM domains protein 2 0 79.597 0.044134 2147200.0 37065.0 31676.0 34766.0 30542.0 39060.0 32802.0 27503.0 31883.0 39592.0 30937.0 False True 36536.44630311145 31602.656168167647 31907.673680640914 32788.16056512525 36762.56759491466 31399.134925196693 28926.97076678746 33364.400574613894 35132.732037757014 36284.41922903871 1.0069458759276777 0.8709704286206624 0.8793767230840766 0.9036429757399733 1.013177787492139 0.8653613752777863 0.7972284352738648 0.9195241727312008 0.9682594563795583 1.0 15.147062557895147 -8.33526448292043 3.2085060111851376 0.9954414794766081 0.9028930243949177 0.20978289773781067 0.061131046486673835 0.38945211002172625 7.376585040496224 0.0596268879632891 0.016295295403159056 4.620995196579181e-09 8.33526448292043 -0.0925484550816904 EQQDVGS(ph)PDK ddPTM_PC-9_Lapatinib_30min_R1 1 EQQDVGSPDK 10 0 F8W9F9;H0Y7T5;Q9Y3S1-2;Q9Y3S1-4;Q9Y3S1;H0Y7R3;A6PVV2;Q9Y3S1-3 F8W9F9 WNK2 Serine/threonine-protein kinase WNK2 1 EQQDVGS(1)PDK 94.781 0.0061701 7198100.0 12289.0 19829.0 16350.0 17788.0 20389.0 16483.0 20111.0 17966.0 14947.0 17199.0 True False 12113.756606473413 19783.08716879012 15005.766112825137 19096.188859028494 19189.759106316298 15778.060513749688 21152.24917612126 18800.76594810757 13263.511461112199 20171.82423377303 0.6005285623197005 0.9807287104786457 0.7438973262369335 0.946676346061769 0.9513150067105735 0.7821831248823293 1.0486036825914204 0.9320310215984363 0.657526622649504 1.0 14.300053939157761 -4.750440763969474 24.954254737290345 0.8916747483213637 0.6005279236785992 0.35384704083386664 0.11880840931905376 525.8873554103917 1193082.9560425782 0.028263813993901894 0.41465890662302035 1.7764755559259805e-05 4.750440763969474 -0.29114682464276453 EQQEAIEHIDEVQNEIDR ddPTM_PC-9_AZD4547_30min_R2 2 EQQEAIEHIDEVQNEIDR 18 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;A0A087X027;P0DME0;Q01105-2 Q01105;Q01105-2 SET;SETSIP Protein SET;Protein SETSIP 0 ; 132.67 3.3583e-05 7869300.0 40749.0 42453.0 50790.0 40923.0 48861.0 53959.0 44836.0 68393.0 50360.0 50094.0 False True 53706.334368146316 56175.1020363375 50116.49141440352 31488.83460404737 42077.49355225233 50584.9352000006 48826.317141158914 57824.43336479028 53021.92678802231 48340.22430742689 1.1110071402770672 1.1620778107913512 1.0367451151173854 0.6514002583808758 0.8704447311757225 1.0464356739078853 1.0100556594574457 1.196197042799122 1.0968490019992756 1.0 15.560936547035684 -7.584631969826383 6.470021293464797 1.1102242569231473 0.975162137769545 0.1211343492386846 0.1406514217146753 0.4500421432397783 36.07707708074288 0.07505294814680465 0.042984362969531245 2.6023639263200962e-08 7.584631969826383 -0.13506211915360233 EQQEAIEHIDEVQNEIDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EQQEAIEHIDEVQNEIDR 18 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;A0A087X027;P0DME0;Q01105-2 Q01105;Q01105-2 SET;SETSIP Protein SET;Protein SETSIP 0 ; 127.91 3.596e-05 7490300.0 64409.0 98283.0 88442.0 88674.0 98733.0 81952.0 84245.0 75875.0 72646.0 67425.0 False True 75312.1715642628 108039.88671028128 90550.79269815289 83705.88326498678 79386.97741077104 77654.29285174921 76264.70371901838 73883.36164620784 73708.31031727038 79648.61876399371 0.9455552743158019 1.3564565009019622 1.1368783803578983 1.0509395462715445 0.9967150547331155 0.97496094793365 0.9575144541426112 0.9276163578571416 0.9254185629467723 1.0 16.281361722849127 -6.026224550606022 1.8719172935607076 0.9562563515456226 1.1689279429207493 0.42402559045569455 0.0951539201650203 0.29212734974719856 2.0507011512668454 0.030094541257496766 0.047652070100869616 9.414027213269887e-07 6.026224550606022 0.2126715913751267 EQQEAIEHIDEVQNEIDR ddPTM_PC-9_Lapatinib_30min_R1 2 EQQEAIEHIDEVQNEIDR 18 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;A0A087X027;P0DME0;Q01105-2 Q01105;Q01105-2 SET;SETSIP Protein SET;Protein SETSIP 0 ; 140.8 0.00013295 10944600.0 36988.0 50694.0 51713.0 44625.0 49479.0 55926.0 59487.0 54946.0 50156.0 46859.0 False True 36460.54433723155 50576.621157630085 47461.35675795272 47906.8713646361 46568.742499456785 53534.17534987348 62566.94578787352 57498.99175023481 44506.90311390534 54958.51571430728 0.6634193784774981 0.9202690520345246 0.8635851267285439 0.8716915066205939 0.847343526188674 0.9740833545826093 1.1384395115966632 1.0462253392928909 0.8098272403364583 1.0 15.746055420813827 -6.805628025303447 4.27824598283487 1.0089048779316314 0.8408885311132063 0.3964445875647584 0.09867297667958148 0.22485654577686295 8.761284896544586 0.03561415264718215 0.03222509235047487 1.5644870574226756e-07 6.805628025303447 -0.16801634681842514 EQQIEEHR ddPTM_PC-9_AZD4547_30min_R2 1 EQQIEEHR 8 0 Q16643-3;Q16643;Q16643-2;D6R9W4 Q16643-3 DBN1 Drebrin 0 131.62 0.0033382 6053900.0 39432.0 43953.0 59522.0 89735.0 75564.0 57700.0 56931.0 61362.0 43929.0 58481.0 False True 51970.555763448065 58159.94770223879 58732.69938901611 69047.98214192978 65073.24292958385 54092.0098786122 61997.748710039225 51879.91285848354 46250.99725716903 56433.597990231065 0.9209151571807352 1.030590814222169 1.0407399400474702 1.2235261369279047 1.1530939944826546 0.9585071979280109 1.0985964198272693 0.9193089702957485 0.8195649206200765 1.0 15.784266712778482 -7.8177715181697955 6.270047427102906 0.8988322627035623 1.0647159638293398 0.349103167480597 0.09200322493076663 0.224072845467953 18.019286834561047 0.05308847903792923 0.025430925769673422 1.5213476985142445e-08 7.8177715181697955 0.16588370112577744 EQQIEEHR ddPTM_PC-9_Lapatinib_30min_R1 2 EQQIEEHR 8 0 Q16643-3;Q16643;Q16643-2;D6R9W4 Q16643-3 DBN1 Drebrin 0 ; 131.62 0.0033382 6638300.0 104516.0 97536.0 110014.0 89244.0 105908.0 96518.0 90223.0 99220.0 110685.0 83696.0 False True 103025.58267411323 97310.16138459383 100969.07358632107 95807.30146925688 99678.69966313921 92390.15013444715 94894.30547547058 103830.12342041825 98218.48973527824 98162.74208209012 1.049538556980779 0.9913146201969042 1.0285885606362148 0.9760047390397524 1.0154433092321458 0.9411936563180402 0.9667038986758718 1.0577345458991834 1.0005679105127432 1.0 16.58288792941599 -12.271636074754593 16.068831674385354 1.0139599098211571 1.0016187587609364 0.0 0.03464100956421918 0.0 0.0 0.0 0.008003994560896184 5.350124954116008e-13 12.271636074754593 -0.012341151060220712 EQQIEEHRR ddPTM_PC-9_AZD4547_30min_R2 1 EQQIEEHRR 9 1 Q16643-3;Q16643;Q16643-2;D6R9W4 Q16643-3 DBN1 Drebrin 0 79.986 0.03997 0.0 4774.5 5378.2 6112.0 8949.1 8951.1 7726.7 6317.7 8125.7 5819.6 8525.9 False True 6292.691684230651 7116.597973566777 6030.95088649014 6886.02325721673 7708.3942722327865 7243.548227540255 6879.963060993396 6870.059775010256 6127.21217505113 8227.41083608199 0.7648447135559989 0.8649863383941335 0.7330314489755279 0.8369611527137438 0.9369161727559522 0.8804164969826321 0.8362245666426125 0.835020872530279 0.7447315196877898 1.0 13.006222771002367 -5.992277381236681 24.888148958646223 0.8647940088509782 0.7936305235479274 0.21969947087312414 0.07031109847890857 310.2262501489003 999771.2030167591 0.019574057509250762 0.028973666627329843 1.017941027660021e-06 5.992277381236681 -0.07116348530305083 EQQIEEHRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EQQIEEHRR 9 1 Q16643-3;Q16643;Q16643-2;D6R9W4 Q16643-3 DBN1 Drebrin 0 70.55199999999999 0.023644 1138100.0 5465.9 3618.3 5390.7 4989.5 7952.7 8081.2 4680.7 5090.1 4892.7 5285.7 False True 6391.168913554079 3977.5009114883615 5519.234732343593 4709.954491177254 6394.425523934627 7657.407645860456 4237.310210666616 4956.490268406751 4964.246481420992 6243.955568421825 1.023576936690064 0.6370162099814052 0.8839324162165032 0.7543222304459329 1.0240984987583492 1.2263712580831008 0.6786259389955278 0.793806140049058 0.7950483354697729 1.0 12.608244555891176 -4.4762585761655975 22.35698597410693 0.8647473971329468 2.774336362084082 0.07312543020863949 0.16834873071081174 418.0886802286996 389528.08662403707 0.042001892287960106 35526.01957591797 3.33996121653249e-05 4.4762585761655975 1.9095889649511353 EQQPSS(ph)ASER ddPTM_PC-9_AZD4547_30min_R2 1 EQQPSSASER 10 0 P12270 P12270 TPR Nucleoprotein TPR 1 EQQPS(0.097)S(0.894)AS(0.008)ER 138.2 0.00011874 2423400.0 13154.0 13130.0 17293.0 25058.0 21170.0 19152.0 12794.0 20899.0 15544.0 16584.0 True False 17336.698379803114 17374.015728855713 17063.683520954528 19281.265242240766 18230.910920799462 17954.422412394826 13932.64121473788 17669.539761243886 16365.624106295063 16003.399207776742 1.0833134982584491 1.0856453371739254 1.066253693944131 1.204823112384222 1.1391899110996542 1.1219130498019445 0.8706051154411876 1.104111666017648 1.0226342475005124 1.0 13.96609075337118 EQQPSS(ph)ASER ddPTM_PC-9_Lapatinib_30min_R1 1 EQQPSSASER 10 0 P12270 P12270 TPR Nucleoprotein TPR 1 EQQPS(0.089)S(0.911)ASER 136.93 1.1415e-05 0.0 14357.0 11789.0 12575.0 8418.1 13077.0 15471.0 16504.0 14324.0 17329.0 12768.0 True False 14152.266547248651 11761.703294813997 11541.132040903743 9037.195155958389 12307.836570371197 14809.341394662468 17358.496365307798 14989.545332332897 15377.225537540193 14974.931787709404 0.9450638405487797 0.7854261683159954 0.7706968021300816 0.6034882351434562 0.8218960022557692 0.9889421604455759 1.1591703128527564 1.000975867191294 1.0268644796205997 1.0 13.870261810960338 -6.77570313375657 3.58067426225222 1.049096767691453 0.7703353681362785 0.6734304813468879 0.08782996606248836 0.13708110970940388 3.7309153627852365 0.03285727588896732 0.030363851562908932 1.6760881910226073e-07 6.77570313375657 -0.27876139955517465 EQQPSSAS(ph)ER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EQQPSSASER 10 0 P12270 P12270 TPR Nucleoprotein TPR 1 EQQPS(0.008)S(0.019)AS(0.974)ER 80.312 0.017828 1658800.0 7091.0 6044.2 7704.7 7258.0 8801.7 7217.1 9038.4 8368.1 8394.5 8370.3 True False 8291.366246366013 6644.228231273793 7888.409268237466 6851.357790753488 7077.070068532121 6838.6225710215695 8182.217319650714 8148.446241734846 8517.253681666258 9887.76913074166 0.8385477185736127 0.6719643372959118 0.7977946454789213 0.692912395117743 0.7157398170360886 0.6916244180661426 0.8275089366934868 0.8240934971267526 0.8613928550562139 1.0 13.271429342849506 -8.378251704658709 0.8361416907775838 0.9955299153521389 0.7335191328891728 0.6979596508952048 0.0529108034475588 0.31704270105397236 0.4922926493918813 0.04874937632542823 0.017998016940002134 4.185509146705957e-09 8.378251704658709 -0.26201078246296605 EQQSWVISPPQPS(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 1 EQQSWVISPPQPSPQK 16 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 EQQSWVIS(0.008)PPQPS(0.992)PQK 140.28 6.3761e-07 0.0 12380.0 11076.0 15651.0 17655.0 19899.0 19403.0 14050.0 16821.0 17000.0 21312.0 True False 16316.582480003233 14656.100397014909 15443.45751381826 13584.912517030913 17136.367331742487 18189.72734271598 15300.422781543462 14221.700958126386 17898.585293812142 20565.873366867927 0.793381452318461 0.7126417699637404 0.7509264128163898 0.6605560714438953 0.8332428691965764 0.8844617011023724 0.7439714574044193 0.6915194265971636 0.8703051397100965 1.0 14.327964719333027 -14.522878745085679 0.2139630219546858 2.1531905907204574 0.7360286412736734 0.5257953573412559 0.06791568382560635 125.66023676564926 1.251586131236135 62.14064397431495 0.1453206893997973 3.0000000013446547e-15 14.522878745085679 -1.417161949446784 EQQSWVISPPQPS(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 1 EQQSWVISPPQPSPQK 16 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 EQQSWVISPPQPS(1)PQK 151.95 1.6992e-10 0.0 18352.0 14101.0 14301.0 14135.0 14888.0 17790.0 8384.4 12510.0 14465.0 10470.0 True False 18090.29711465537 14068.350000862862 13125.22698345642 15174.535052977713 14012.317110934184 17029.163170515487 8818.503206815729 13091.260270000315 12835.799376797211 12279.725549601937 1.4731841555890302 1.1456567122804227 1.0688534471262585 1.2357389415327458 1.14109367138001 1.3867706653319714 0.7181352035267263 1.0660873662949808 1.0452838970178207 1.0 13.583990696556164 -7.250070997533203 24.999372788414295 0.9628838858421961 1.224783428217107 0.4849114567047704 0.1429553398024246 693.6257814306542 1525303.6080983768 0.05456736543006231 0.04189129231310002 5.622494023469019e-08 7.250070997533203 0.261899542374911 EQS(ph)GTIYLQHADEER ddPTM_PC-9_Lapatinib_30min_R1 1 EQSGTIYLQHADEER 15 0 M0QXN5;P37198 M0QXN5 NUP62 Nuclear pore glycoprotein p62 1 EQS(0.499)GT(0.499)IY(0.001)LQHADEER 69.081 0.015008 2065700.0 7763.4 9107.0 11098.0 7289.8 13116.0 10540.0 4602.9 10609.0 11237.0 7311.1 True False 7652.692492366799 9085.913301032413 10185.565279518863 7825.9162100599215 12344.542667048154 10089.228769940044 4841.215639837328 11101.932870058621 9971.370729144162 8574.813893571602 0.8924616425907387 1.0596047230650656 1.1878468041335353 0.9126630976710624 1.4396280572692846 1.176611981923453 0.5645855058693121 1.294714148651268 1.1628673056822303 1.0 13.065889644258325 -4.785146288634357 4.114608139620983 1.0947152104236044 0.8764783613374243 0.06591121995172244 0.22411526500609724 0.6651865863613092 21.789142489104925 0.05661797104891104 0.4236270804501642 1.640037246674297e-05 4.785146288634357 -0.21823684908618013 EQS(ph)NDIAR ddPTM_PC-9_Lapatinib_30min_R1 1 EQSNDIAR 8 0 P45973 P45973 CBX5 Chromobox protein homolog 5 1 EQS(1)NDIAR 72.34 0.032948000000000005 5542000.0 26635.0 21310.0 25166.0 22835.0 20802.0 23282.0 17404.0 17377.0 30200.0 21034.0 True False 26255.180015739195 21260.658004282486 23096.948623569275 24514.362075326924 19578.467258305544 22286.283132992783 18305.093961573974 18184.398857857344 26798.557979901543 24669.698873956753 1.0642683621670064 0.8618126274223349 0.9362476916145986 0.9937033362497256 0.7936240875227744 0.9033869139164853 0.7420071908902889 0.7371147475599795 1.0862944909389298 1.0 14.590452485309063 -6.251790730694558 24.826039678544188 0.8584895562345841 0.9547254551243535 0.10868867934470161 0.11355031170171923 1272.2954216894002 3273623.0104584545 0.03298152071663449 0.04202585118507307 5.600273915027657e-07 6.251790730694558 0.09623589888976936 EQS(ph)TPPKSPQ ddPTM_PC-9_AZD4547_30min_R2 2 EQSTPPKSPQ 10 1 Q92615;H0Y4V9;A0A087X183 Q92615 LARP4B La-related protein 4B 1 EQS(0.909)T(0.091)PPKSPQ;EQS(0.925)T(0.075)PPKSPQ 134.38 0.00053761 50886000.0 99793.0 85519.0 132721.0 185524.0 157854.0 127133.0 102788.0 141990.0 119760.0 136958.0 True False 131525.09817665268 113161.34433480658 130961.03282163909 142754.3081172272 135938.6968583789 119183.3534124367 111935.93287325889 120048.7081056041 126090.26910511433 132163.14210677048 0.9951723005374499 0.8562246820931895 0.9909043530142447 1.0801370627364506 1.0285673803711346 0.901789648101376 0.8469527213784713 0.9083372731000939 0.9540501768885756 1.0 17.011960366003912 -6.77640286150196 24.92860059888525 0.9117924481302386 0.987793525502252 0.20940900984737087 0.0643791888043249 368.58215933670175 614040.3744439357 0.024504244189550974 0.021696423491037273 1.6733898810851336e-07 6.77640286150196 0.07600107737201334 EQS(ph)TPPKSPQ ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EQSTPPKSPQ 10 1 Q92615;H0Y4V9;A0A087X183 Q92615 LARP4B La-related protein 4B 1 EQS(0.498)T(0.498)PPKS(0.005)PQ;EQS(0.92)T(0.08)PPKSPQ 141.71 0.00060562 74056000.0 101385.0 100293.0 110066.0 132365.0 139862.0 131131.0 127423.0 119565.0 112020.0 96820.0 True False 118547.47805497357 110249.42622665405 112690.3908676296 124949.01818311989 112457.04510776752 124254.25951706758 115352.57097736919 116426.54543958901 113658.08057898103 114372.69957330155 1.0365015296241775 0.9639487975536951 0.9852909941625208 1.0924724051218182 0.9832507716204926 1.0863978902363227 1.008567353990273 1.017957483507427 0.9937518394075981 1.0 16.803383200587014 EQS(ph)TPPKSPQ ddPTM_PC-9_Lapatinib_30min_R1 3 EQSTPPKSPQ 10 1 Q92615;H0Y4V9;A0A087X183 Q92615 LARP4B La-related protein 4B 1 EQS(0.499)T(0.499)PPKS(0.002)PQ;EQS(0.4)T(0.4)PPKS(0.2)PQ;EQS(0.908)T(0.092)PPKSPQ 135.1 0.00054426 108119000.0 260886.0 189415.0 205591.0 194429.0 196062.0 165652.0 146707.0 145706.0 177644.0 130319.0 True False 257165.7177993676 188976.42120512293 188688.1015842102 208727.95725613006 184530.01863272273 158567.4501136725 154302.77061713598 152476.03268590476 157635.86204574915 152844.46551084737 1.6825320886814612 1.23639688603387 1.2345105264594551 1.365623259949289 1.2073058583833816 1.0374431915718858 1.0095411050796936 0.9975894918817557 1.0313481846980042 1.0 17.22170478770446 -1.5228787452806396 0.28959771157816955 0.9671999370602775 5.9079611705534845 0.7978728842109853 0.09334083703706646 24.947375394304423 0.3539297453583384 0.1061448551062333 63.08787859748631 0.029999999999979137 1.5228787452806396 4.940761233493207 EQSEGVGAR ddPTM_PC-9_Lapatinib_30min_R1 1 EQSEGVGAR 9 0 O00625 O00625 PIR Pirin 0 93.598 0.028257 2213700.0 11804.0 7747.5 12301.0 7545.7 10016.0 9425.2 8612.6 12811.0 13026.0 8118.4 False True 11635.67279541151 7729.561139754979 11289.659263233158 8100.635949717296 9426.878572213649 9022.106167214319 9058.518286224547 13406.245828854846 11558.874710138989 9521.654622911974 1.2220221438627452 0.811787598465851 1.1856825006093827 0.8507592714216625 0.9900462624982989 0.9475355413022868 0.9513596790653401 1.4079743867830885 1.2139565199440072 1.0 13.21699658391457 -7.739191059799256 24.984547243782178 1.2332241615630735 0.9870534171505296 0.286128975261036 0.15234998112360926 230.2061722160089 258518.7085389142 0.0663768061718288 0.03828524175667692 1.823093489718837e-08 7.739191059799256 -0.24617074441254383 EQSEVSVS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 EQSEVSVSPR 10 0 Q7L4I2;E9PI52 Q7L4I2 RSRC2 Arginine/serine-rich coiled-coil protein 2 1 EQSEVS(0.002)VS(0.998)PR;EQSEVSVS(1)PR 204.32 7.7384e-05 546830000.0 73815.0 59544.0 85511.0 120194.0 111007.0 96177.0 81465.0 84766.0 88363.0 87902.0 True False 97286.63455262022 78790.4335536165 84377.06826810515 92485.13027878867 95595.59417029702 90163.0369860536 88715.22718138364 71667.36242890092 93033.68778336018 84824.57773528657 1.1469156363645474 0.9288632570562164 0.9947242947842551 1.0903105296605013 1.1269799004319683 1.0629352882536809 1.0458670063556188 0.8448891151872799 1.0967774938260455 1.0 16.372194722632187 -10.91237704940225 3.30930251963835 0.9996920888788751 1.0326281457797184 0.013294174519819957 0.08828922267769618 33061227.520148154 80015.05702424199 78395.23118879973 0.021615724015487125 1.2235534631628078e-11 10.91237704940225 0.032936056900843336 EQSEVSVS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EQSEVSVSPR 10 0 Q7L4I2;E9PI52 Q7L4I2 RSRC2 Arginine/serine-rich coiled-coil protein 2 1 EQSEVSVS(1)PR;EQS(0.002)EVS(0.013)VS(0.985)PR;EQSEVS(0.002)VS(0.998)PR;EQSEVS(0.001)VS(0.999)PR 187.78 0.00015919 499686000.0 156093.0 173064.0 175704.0 197027.0 204089.0 154083.0 170847.0 183792.0 161169.0 139691.0 True False 182516.46192272054 190244.65017986967 179893.4497211308 185988.21596015277 164099.22551514502 146002.61623238094 154663.13533483457 178967.6547437211 163525.79172320815 165015.8725066522 1.1060539762037913 1.1528869755980622 1.0901584616587647 1.1270928858837814 0.9944450980527935 0.8847792276860834 0.9372621735439403 1.0845481227056293 0.9909700760247534 1.0 17.332245275182373 -6.292987217128237 5.549597641962745 0.9782780978663776 1.11971249566033 0.6460958445291677 0.04970829936203306 0.12998327209410018 11.960498846240839 0.016863171991307862 0.019679984189983117 5.093458627444002e-07 6.292987217128237 0.14143439779395228 EQSEVSVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 EQSEVSVSPR 10 0 Q7L4I2;E9PI52 Q7L4I2 RSRC2 Arginine/serine-rich coiled-coil protein 2 1 EQSEVS(0.001)VS(0.999)PR;EQSEVSVS(1)PR;EQSEVS(0.002)VS(0.998)PR;EQSEVS(0.003)VS(0.996)PR 166.45 0.00016792 496504000.0 161761.0 144444.0 167716.0 154524.0 174605.0 145722.0 149487.0 139564.0 159543.0 132206.0 True False 159454.25847666585 144109.54879261297 153927.03788248217 165888.21043695277 164335.07718663788 139489.8097545733 157226.7054144913 146048.6529434314 141573.58727772953 155057.63094657805 1.0283547962344566 0.9293934643065905 0.9927085622475078 1.0698487357523614 1.059832245491073 0.8995997739874646 1.013988827603464 0.9418991638905504 0.9130385032549984 1.0 17.24244500237304 -6.757112328492487 24.99998237071456 0.9538416770954953 1.012909113387188 0.29078989072757644 0.048542132480392436 164.64764171471592 951269.0785928675 0.017146816436122283 0.016582580917506817 1.7493941564567805e-07 6.757112328492487 0.05906743629169264 EQSGSSNGSESS(ph)PANENGDR ddPTM_PC-9_AZD4547_30min_R2 1 EQSGSSNGSESSPANENGDR 20 0 Q9UPU5;A0A0U1RQI9 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 EQSGSSNGSES(0.027)S(0.973)PANENGDR 260.49 1.9532999999999992e-157 0.0 925.72 973.76 862.07 872.39 1165.5 2149.3 1117.9 879.89 923.36 2172.5 True False 1220.079703827834 1288.5088770853406 850.6383885334687 671.273963791141 1003.6904429944155 2014.9039312322566 1217.3909343407438 743.9232183607288 972.1669245231997 2096.441436257535 0.5819765259008909 0.6146171578184049 0.4057534705343293 0.32019685939306114 0.4787591132458032 0.9611067098679202 0.5806939861453849 0.3548504649329696 0.46372243350554293 1.0 11.033726813963527 -6.583914215242365 24.999947538734375 0.636473916580105 0.4741721163095481 0.17268023815130018 0.20237094922581703 157.79058543748374 64628.93848260768 0.07003182586978669 0.07003183193479343 2.6066683857653306e-07 6.583914215242365 -0.1623018002705569 EQSGSSNGSESS(ph)PANENGDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EQSGSSNGSESSPANENGDR 20 0 Q9UPU5;A0A0U1RQI9 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 EQSGSSNGSES(0.103)S(0.897)PANENGDR;EQSGSSNGSES(0.05)S(0.95)PANENGDR 254.54 4.902599999999999e-157 1402900.0 5777.4 6274.3 7588.99 6650.3 7521.6 5868.46 4893.97 3421.79 5773.6 3849.8 True False 6755.39971114864 6897.17103859587 7769.94030300485 6277.705251563501 6047.796474257383 5560.707626766602 4430.377732325523 3331.9716381861904 5858.027977421918 4547.738264999971 1.4854416233975336 1.516615653032951 1.7085284706913315 1.3804016163105952 1.329847084825015 1.2227413502581237 0.9741936483949238 0.7326656557677274 1.2881189804844575 1.0 12.1509335101648 -6.697608631332031 1.28893668414988 0.9774330284938606 1.5505555362509933 0.7170867339374527 0.14727135595190902 0.22386824417977183 0.7815317754213594 0.0689732530532699 0.06596154398941662 2.0062791908464023e-07 6.697608631332031 0.5731225077571327 EQSGSSNGSESS(ph)PANENGDR ddPTM_PC-9_Lapatinib_30min_R1 1 EQSGSSNGSESSPANENGDR 20 0 Q9UPU5;A0A0U1RQI9 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 EQSGSSNGSES(0.041)S(0.959)PANENGDR 198.6 2.3914e-59 0.0 844.61 2160.7 2082.2 405.55 1115.1 1148.0 1983.0 1295.0 2840.7 731.23 True False 832.5657065174952 2155.6970319030124 1911.0095535244345 435.37549987514075 1049.51201037095 1098.9027161187062 2085.6700371064826 1355.1704276299288 2520.7504521028577 857.6221311972713 0.9707838408451559 2.5135743977287315 2.2282652044631783 0.5076542267715747 1.223746417208 1.2813367054609452 2.431921893380727 1.5801486206262683 2.9392320468500497 1.0 9.744198325230608 -7.248623179635271 24.732777856508005 2.0361713797079584 1.484060120552347 0.11406976904437027 0.7206363176427596 1538.7376563322996 2969469.2437509187 0.2805016936246898 0.2157740442420771 5.6412691443703725e-08 7.248623179635271 -0.5521112591556114 EQSGT(ph)PSCENLK ddPTM_PC-9_AZD4547_30min_R2 1 EQSGTPSCENLK 12 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5 Q8NEV8-2 EXPH5 Exophilin-5 1 EQS(0.001)GT(0.674)PS(0.326)CENLK 150.11 0.00041681 2390800.0 22694.0 21542.0 29302.0 38387.0 35780.0 33720.0 30485.0 37264.0 33552.0 37076.0 True False 29910.219935476045 28505.030223229965 28913.436334413334 29537.470223237917 30812.56460775646 31611.483069441994 33198.10594272975 31505.70504153271 35325.4902222344 35777.98052505609 0.8359951986258496 0.79671993234127 0.808134945295882 0.8255767874475808 0.8612158695256082 0.8835457621009043 0.927892112845229 0.8805892501246286 0.9873528271808187 1.0 15.126784336846745 -7.445517595735539 0.4716827229330355 1.0027406851264549 0.7984112476824604 0.8784608252482597 0.023536060290717094 0.3114897382486453 0.15751155652700707 0.023620934276167366 0.020386845663839886 3.584944233375661e-08 7.445517595735539 -0.20432943744399445 EQSGT(ph)PSCENLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EQSGTPSCENLK 12 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5 Q8NEV8-2 EXPH5 Exophilin-5 1 EQS(0.279)GT(0.69)PS(0.03)CENLK;EQS(0.008)GT(0.927)PS(0.065)CENLK 101.2 0.0052493999999999996 0.0 24015.0 19095.1 17712.699999999997 28282.0 32098.0 31853.0 30936.0 31961.0 30569.0 22171.6 True False 28080.265182129442 20990.73533288048 18135.037943788822 26697.45123148112 25808.627317420942 30182.57260599825 28005.518122755653 31122.057615478716 31016.013794133763 26191.135569710972 1.0721285874524347 0.8014442625830797 0.6924112891371265 1.0193315658430513 0.9853955071450821 1.1523964864243312 1.0692746806726068 1.1882668291584182 1.1842179851874226 1.0 14.676790991558486 -6.317644042231491 1.7396299277392397 1.1261295363819364 0.8582934742170388 0.4790904147368378 0.110525562465643 0.29255921100332943 1.7513323359385602 0.040147209072252124 0.051176065582386965 4.812336170175199e-07 6.317644042231491 -0.2678360621648975 EQSGT(ph)PSCENLK ddPTM_PC-9_Lapatinib_30min_R1 3 EQSGTPSCENLK 12 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5 Q8NEV8-2 EXPH5 Exophilin-5 1 EQS(0.058)GT(0.908)PS(0.034)CENLK;EQS(0.001)GT(0.913)PS(0.086)CENLK;EQS(0.007)GT(0.956)PS(0.036)CENLK 128.76 0.00047729 3116800.0 55740.2 58301.0 60974.0 53654.0 62207.0 51667.0 44295.6 50717.2 56553.0 43411.4 True False 54945.3345264992 58166.007616502735 55960.95308644651 57599.89414449713 58548.106563667614 49457.32285165959 46589.00942796463 53073.70626424137 50183.405610509006 50915.00264794549 1.0791580412245416 1.1424139171453 1.0991053751561504 1.1312951222407799 1.1499185607138553 0.9713703285775098 0.9150349996072243 1.042398183325696 0.985631012483783 1.0 15.635803203956984 -6.766184439303078 24.999999999995996 0.9812960248870786 1.1210270874475208 0.7944700251508126 0.03496038168224485 52.80790579842724 278223.95849001216 0.012282437766350712 0.011184433324023395 1.7132295663381244e-07 6.766184439303078 0.1397310625604422 EQSSDLTPSGDVS(ph)PVKPLSR ddPTM_PC-9_AZD4547_30min_R2 4 EQSSDLTPSGDVSPVKPLSR 20 1 Q8WYQ5-3;Q8WYQ5 Q8WYQ5-3 DGCR8 Microprocessor complex subunit DGCR8 1 EQSSDLTPSGDVS(0.99)PVKPLS(0.01)R;EQSSDLTPSGDVS(0.996)PVKPLS(0.004)R;EQSSDLTPSGDVS(0.991)PVKPLS(0.009)R;EQSSDLTPSGDVS(0.983)PVKPLS(0.017)R 128.33 8.0726e-06 153972000.0 205856.0 194124.0 249810.0 274927.0 279408.0 251485.0 241099.0 280132.0 253458.0 269052.0 True False 271313.9259292043 256870.78669827766 246497.3561770455 211546.82772980808 240617.02213314758 235759.6031945024 262556.34392934834 236844.03619296456 266855.27243523765 259632.5713730554 1.0449918686795443 0.9893627187830396 0.949408446226354 0.8147931001532358 0.9267597700113475 0.9080509504169609 1.0112611932348499 0.912227749162693 1.0278189328248968 1.0 17.98611185781521 -8.269562088649518 24.63566172435003 1.0139094780782518 0.9423401187204256 0.1730360392174095 0.06043924401263609 1007.8590772323724 3056723.7596898605 0.05783825900555062 0.01600257286266849 5.375735737455129e-09 8.269562088649518 -0.07156935935782627 EQSSDLTPSGDVS(ph)PVKPLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EQSSDLTPSGDVSPVKPLSR 20 1 Q8WYQ5-3;Q8WYQ5 Q8WYQ5-3 DGCR8 Microprocessor complex subunit DGCR8 1 EQSSDLTPSGDVS(0.993)PVKPLS(0.007)R;EQSSDLTPSGDVS(0.998)PVKPLS(0.002)R;EQSSDLTPS(0.001)GDVS(0.892)PVKPLS(0.107)R;EQSSDLTPS(0.001)GDVS(0.999)PVKPLS(0.001)R 159.76 4.2856e-06 113716000.0 176228.0 198366.0 188188.0 219331.0 231375.0 194038.0 219635.0 185796.0 191068.0 157871.0 True False 206059.9197383424 218058.46552477666 192675.11562696475 207042.5951506964 186038.72968933487 183862.30569562304 198829.58278030241 180919.05186713478 193862.0080348569 186491.76259385142 1.1049277290981867 1.1692659369608316 1.0331561724073555 1.1101969988969504 0.9975707618491269 0.9859004126420591 1.066157453899563 0.9701181936981683 1.039520487867642 1.0 17.508752381981893 -5.759023824639457 1.0780915482164062 1.0098855045492552 1.1368526934126921 0.5470816780167662 0.04104954952461154 0.4255722526508519 0.9476478330160106 0.014739576996129404 0.042324816273707364 1.7417113235187497e-06 5.759023824639457 0.12696718886343694 EQSSDLTPSGDVS(ph)PVKPLSR ddPTM_PC-9_Lapatinib_30min_R1 3 EQSSDLTPSGDVSPVKPLSR 20 1 Q8WYQ5-3;Q8WYQ5 Q8WYQ5-3 DGCR8 Microprocessor complex subunit DGCR8 1 EQSSDLTPSGDVS(0.999)PVKPLS(0.001)R;EQSSDLTPSGDVS(0.925)PVKPLS(0.075)R;EQSSDLTPSGDVS(0.991)PVKPLS(0.009)R 161.56 2.1203e-06 126699000.0 219594.0 196572.0 200013.0 192194.0 220843.0 198644.0 179399.0 183994.0 185316.0 176459.0 True False 216462.54929139285 196116.8496113477 183568.70321250765 206328.58790038896 207853.44893404323 190148.45918178066 188687.4024139513 192543.03294312066 164443.76061600767 206959.7030331618 1.0459164084551686 0.947608866543084 0.8869779987222628 0.9969505409820205 1.004318453726899 0.9187704485221097 0.911710828961314 0.9303406901017292 0.7945689822992177 1.0 17.658990363447963 -6.907747005388431 6.267739940014338 0.9049747405614634 0.9707499366887952 0.22103766954931003 0.06077958151287572 0.3449064606109322 19.360934872081526 0.021474633986450987 0.018916518763594868 1.2366676340191544e-07 6.907747005388431 0.06577519612733174 EQSSDLTPSGDVSPVKPLS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 EQSSDLTPSGDVSPVKPLSR 20 1 Q8WYQ5-3;Q8WYQ5 Q8WYQ5-3 DGCR8 Microprocessor complex subunit DGCR8 1 EQSSDLTPSGDVS(0.357)PVKPLS(0.643)R 147.28 8.0135e-05 26039000.0 56041.0 55210.0 59983.0 53111.0 57804.0 49203.0 49242.0 56822.0 57376.0 58847.0 True False 55241.84506333929 55082.164637092304 55051.4292810759 57016.960113102214 54404.08236703652 47098.702387795034 51791.50981704357 59462.15755890949 50913.71068393481 69018.6255413014 0.8003903965065495 0.7980768119488356 0.7976314922141213 0.8261097590096563 0.7882521846871697 0.6824056842396945 0.7503990323025346 0.8615378398592821 0.7376807388531312 1.0 16.074698123324435 -10.846391324043761 3.232068536569292 1.0013971278063603 0.7832901356837856 0.6589074559762049 0.04694390224734418 46795414.839164294 63048138.924280636 629751.4225144353 0.013142600766136056 1.4243236185836126e-11 10.846391324043761 -0.21810699212257467 EQSSEAAETGVS(ph)ENEENPVR ddPTM_PC-9_AZD4547_30min_R2 1 EQSSEAAETGVSENEENPVR 20 0 Q29RF7 Q29RF7 PDS5A Sister chromatid cohesion protein PDS5 homolog A 1 EQSSEAAET(0.169)GVS(0.831)ENEENPVR 138.04 0.00014477 11304000.0 31902.0 36492.0 51464.0 62388.0 43643.0 39924.0 43891.0 56911.0 38467.0 39193.0 True False 42046.17239717798 48287.32536004589 50781.55373401977 48005.410484991495 37583.92278301611 37427.54596869519 47797.21397186653 48116.712634678726 40500.287088063065 37820.86499942077 1.1117189519018646 1.2767377309002692 1.342686206008178 1.269283779885169 0.9937351454968496 0.9896004750094528 1.2637789741878867 1.2722266567783584 1.0708450768823856 1.0 15.206894739032363 -14.522878744950638 0.0923555694070333 0.4298631833920709 1.32094163262694 0.19366841511806243 0.11874159160004084 394.65286130843145 2.5110912918179995 44.29476029389404 2.8857866793691733 3.0000000022774807e-15 14.522878744950638 0.8910784492348691 EQSSEAAETGVS(ph)ENEENPVR ddPTM_PC-9_Lapatinib_30min_R1 1 EQSSEAAETGVSENEENPVR 20 0 Q29RF7 Q29RF7 PDS5A Sister chromatid cohesion protein PDS5 homolog A 1 EQSSEAAET(0.055)GVS(0.945)ENEENPVR 127.07 2.1272e-05 11053000.0 24571.0 29411.0 30702.0 29498.0 28127.0 26440.0 32234.0 27190.0 31772.0 22816.0 True False 24220.613034230457 29342.90063650647 28177.80007314724 31667.38132244337 26472.62515980963 25309.22283465035 33902.91879782669 28453.34666197509 28193.502786007663 26759.715199591017 0.9051147537848472 1.0965326206818125 1.0529932722743587 1.1833975468814915 0.9892715584736204 0.9457956725577246 1.2669387003918804 1.063290339592626 1.053580076459056 1.0 14.707775141181882 EQST(ph)PPKSPQ ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EQSTPPKSPQ 10 1 Q92615;H0Y4V9;A0A087X183 Q92615 LARP4B La-related protein 4B 1 EQS(0.009)T(0.976)PPKS(0.015)PQ 113.63 0.013182 42825000.0 85692.0 75401.0 100280.0 104770.0 102960.0 108330.0 96825.0 99959.0 94376.0 77983.0 True False 100197.96310585186 82886.31297215087 102671.05551401775 98900.07656892289 82785.72710454417 102648.98409593423 87653.03504770536 97335.182165315 95756.0704581495 92120.70058691151 1.0876812971186627 0.8997577357105699 1.1145275150958331 1.0735923189773764 0.8986658435846324 1.1142879227138507 0.9515020455691051 1.0566048840833975 1.0394631157609162 1.0 16.491237762558406 EQST(ph)PPKSPQ ddPTM_PC-9_Lapatinib_30min_R1 1 EQSTPPKSPQ 10 1 Q92615;H0Y4V9;A0A087X183 Q92615 LARP4B La-related protein 4B 1 EQS(0.048)T(0.824)PPKS(0.128)PQ 100.93 0.039123000000000005 53715000.0 58450.0 48793.0 48380.0 47071.0 48443.0 52848.0 54253.0 49461.0 51159.0 43324.0 True False 57616.49228158276 48680.02280633299 44402.383152200666 50532.75836425289 45593.6779826024 50587.81423470506 57061.95487803225 51759.13862625784 45396.9346918471 50812.495674398684 1.1339040036683772 0.9580325107089728 0.8738477133012051 0.9944947142148199 0.8972926320085134 0.99557822467266 1.1229905975034067 1.0186301211797417 0.8934206849973685 1.0 15.632895703922378 -6.9938258213450215 24.94274505919055 1.0173088000228154 0.9645980254699816 0.03624727961739571 0.08317771047263006 442.3767546680546 1787122.9200047525 0.030046487024065604 0.02642317434556338 1.0143181077826117e-07 6.9938258213450215 -0.052710774552833795 EQSTPPKS(ph)PQ ddPTM_PC-9_AZD4547_30min_R2 2 EQSTPPKSPQ 10 1 Q92615;H0Y4V9;A0A087X183 Q92615 LARP4B La-related protein 4B 1 EQS(0.066)T(0.387)PPKS(0.548)PQ;EQS(0.005)T(0.152)PPKS(0.843)PQ 108.56 0.0096998 59524800.0 67745.0 64671.0 73922.0 97366.0 79120.0 66847.1 69056.0 86283.0 72027.0 69005.0 True False 89286.50081646352 85574.63603966686 72941.74598022322 74919.77298970443 68135.55371061196 62667.14026961147 75201.85022080199 72949.944936093 75834.20017396509 66589.15595348734 1.340856473369783 1.2851136917764947 1.0953997679618162 1.125104709872521 1.0232229667876371 0.9411012855213932 1.1293407934668918 1.0955228954553604 1.1388370837277983 1.0 16.022999633033315 -5.2022314754985235 1.7963362889366437 1.0628296587968082 1.35967060464072 0.7336583022315488 0.05961106985035549 0.2402290693576278 1.3006786895986286 0.01799649438483058 0.09043040327586917 6.277236979059762e-06 5.2022314754985235 0.29684094584391185 EQSTPPKS(ph)PQ ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EQSTPPKSPQ 10 1 Q92615;H0Y4V9;A0A087X183 Q92615 LARP4B La-related protein 4B 1 EQS(0.004)T(0.226)PPKS(0.769)PQ 100.93 0.018328 17258000.0 34719.0 35921.0 36896.0 48559.0 48471.0 43670.0 44103.0 49770.0 42814.0 35145.0 True False 40596.24096849269 39486.99948638129 37775.74056885919 45838.396660402126 38973.455501984914 41379.868323358656 39925.24456193082 48463.590235673946 43440.073753869685 41516.510292333056 0.9778336541929846 0.9511155732584162 0.9098968170221021 1.1041004250510718 0.9387459405320545 0.9967087318271152 0.9616714960097188 1.167332945240916 1.0463324939401724 1.0 15.341397561310451 -7.731650708904337 24.997711142870134 1.0801246484335776 0.9777224840701627 0.32221445481869904 0.06211610684060976 205.81809117176144 172716.15560767846 0.02821564969308663 0.016287691227650215 1.855022967514889e-08 7.731650708904337 -0.10240216436341487 EQT(ph)VSETLGPGGEAVR ddPTM_PC-9_AZD4547_30min_R2 1 EQTVSETLGPGGEAVR 16 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 EQT(0.818)VS(0.107)ET(0.075)LGPGGEAVR 200.73 6.098e-12 13149000.0 15997.0 19218.0 26227.0 25657.0 29856.0 27496.0 19929.0 28980.0 26215.0 22520.0 True False 21083.713241729525 25429.842671526952 25879.212843582616 19742.17504669852 25711.00975207316 25776.670773350463 21702.64239241138 24501.806894150326 27600.67138101679 21731.581654554513 0.9701877008713166 1.1701791004336473 1.190857308729705 0.9084555077729903 1.1831172788421793 1.1861387350031276 0.9986683315276748 1.1274746258064114 1.2700719082373937 1.0 14.407505559229357 -7.996588613300435 24.994626863172094 1.1562817352859092 1.092417957977759 0.025216166967266362 0.11300028647996657 311.4411021451405 2281878.627833587 0.06041024453763073 0.028785991548986416 1.0078859396735122e-08 7.996588613300435 -0.06386377730815007 EQT(ph)VSETLGPGGEAVR ddPTM_PC-9_Lapatinib_30min_R1 2 EQTVSETLGPGGEAVR 16 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 EQT(0.971)VS(0.029)ETLGPGGEAVR;EQT(0.945)VS(0.055)ET(0.001)LGPGGEAVR 192.22 1.6891999999999998e-29 12292000.0 71636.0 68584.0 79912.0 61399.0 55883.0 62119.0 49439.0 51790.0 69045.0 42908.0 True False 70614.45750356666 68425.19796178848 73341.94382924068 65914.48728105977 52596.07181020518 59462.31517646161 51998.70951311512 54196.35246869034 61268.42502391731 50324.59062868386 1.403179968707347 1.359677189759149 1.4573778527159535 1.3097868548480558 1.0451366052489384 1.181575735313969 1.0332664183357918 1.076935784109482 1.2174649462323837 1.0 15.618975910970882 -6.109218411379191 3.9158565071205316 1.098290689082703 1.4006582195341524 0.8243665334316292 0.06651934615245578 0.09205500967930819 2.4831268135834543 0.019329282314479508 0.02588176979352118 7.776453664402098e-07 6.109218411379191 0.30236753045144926 EQTLS(ph)PTITSGLHNIAR ddPTM_PC-9_AZD4547_30min_R2 4 EQTLSPTITSGLHNIAR 17 0 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;H7BXG7;O94979-7;O94979-6;O94979-10;O94979-4;H0Y8W8 D6REX3 SEC31A Protein transport protein Sec31A 1 EQT(0.121)LS(0.867)PT(0.012)ITSGLHNIAR;EQT(0.305)LS(0.606)PT(0.086)IT(0.003)SGLHNIAR;EQT(0.27)LS(0.681)PT(0.048)IT(0.001)SGLHNIAR;EQT(0.027)LS(0.777)PT(0.197)ITSGLHNIAR 158.91 1.4330999999999999e-05 79045000.0 58570.0 62292.0 140469.0 221207.0 170942.0 146692.0 107405.0 181911.0 125004.0 138506.0 True False 77194.041668319 82426.67081354761 138606.28927918576 170211.1437640812 147209.65397370313 137519.32605049206 116963.83692894496 153800.83484892253 131611.45623927598 133656.9470979452 0.5775535304704393 0.6167032287004467 1.0370301902647352 1.2734926800276885 1.1013991952534001 1.0288977044322019 0.875104807258785 1.1507133612457545 0.9846959630375945 1.0 17.028175301043454 -5.260965569081931 5.092667063418071 1.0652929879721764 0.5892600196400859 0.7709687255609123 0.10023209866332672 0.07693377878834032 6.568119120049099 0.0275737407586725 0.06791056919215191 5.483204341068031e-06 5.260965569081931 -0.4760329683320905 EQTLS(ph)PTITSGLHNIAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EQTLSPTITSGLHNIAR 17 0 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;H7BXG7;O94979-7;O94979-6;O94979-10;O94979-4;H0Y8W8 D6REX3 SEC31A Protein transport protein Sec31A 1 EQT(0.251)LS(0.748)PT(0.001)ITSGLHNIAR;EQT(0.187)LS(0.813)PT(0.001)ITSGLHNIAR;EQT(0.212)LS(0.787)PT(0.001)ITSGLHNIAR 201.16 5.516899999999999e-13 56969000.0 52964.0 71117.0 110060.0 121522.0 152758.0 131619.0 114084.0 108865.0 112238.0 83826.0 True False 61929.75911331682 78177.02576412079 112684.2478048746 114713.51631963982 122826.1664824784 124716.66793799268 103277.13762336594 106007.40910200201 113879.26841656525 99022.99023374903 0.6254078872707068 0.7894835894127188 1.1379604629074263 1.1584533657169154 1.2403803015091819 1.2594718422822049 1.0429612091048226 1.0705333059703195 1.1500285756645723 1.0 16.595475895101437 -5.137306863052532 2.790613036181054 1.1435551182087993 0.6389529732018149 0.8312247511657197 0.07802195085122988 0.11017921557360992 1.581697142991059 0.022027358872547687 0.08528227358065708 7.289422734630908e-06 5.137306863052532 -0.5046021450069844 EQTLS(ph)PTITSGLHNIAR ddPTM_PC-9_Lapatinib_30min_R1 3 EQTLSPTITSGLHNIAR 17 0 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;H7BXG7;O94979-7;O94979-6;O94979-10;O94979-4;H0Y8W8 D6REX3 SEC31A Protein transport protein Sec31A 1 EQT(0.145)LS(0.474)PT(0.38)ITSGLHNIAR;EQT(0.235)LS(0.764)PTITSGLHNIAR;EQT(0.066)LS(0.591)PT(0.335)IT(0.008)SGLHNIAR 139.0 3.2981e-05 44547000.0 78937.0 63350.0 112573.0 68388.0 97866.0 101487.0 72312.0 82143.0 110880.0 68598.0 True False 77811.34390472698 63203.31696721242 103317.6824843464 73417.4816556804 92109.71429195907 97146.63758775187 76055.96153466665 85959.66365776447 98391.52678183716 80455.07289891054 0.96714030701948 0.7855728009422793 1.28416616580737 0.9125276879424039 1.144858999850665 1.2074644156971157 0.9453221381109027 1.0684181936640624 1.222937513281024 1.0 16.295895768992473 -5.244331319673365 24.975781618775663 1.0941313219892816 0.8763565506891449 0.3450147477077342 0.12216845258615262 881.4718904136744 1286841.9545987616 0.02955604061843254 0.07776894392558241 5.697294645431692e-06 5.244331319673365 -0.21777477130013678 EQTLSPT(ph)ITSGLHNIAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EQTLSPTITSGLHNIAR 17 0 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;H7BXG7;O94979-7;O94979-6;O94979-10;O94979-4;H0Y8W8 D6REX3 SEC31A Protein transport protein Sec31A 1 EQT(0.01)LS(0.031)PT(0.925)IT(0.026)S(0.008)GLHNIAR;EQT(0.014)LS(0.124)PT(0.858)IT(0.005)SGLHNIAR 140.27 0.00018343 19108000.0 31341.0 30055.7 56175.0 50598.0 64597.0 62449.0 51539.0 54184.0 54311.0 45956.0 True False 36646.41228703386 33039.43126479861 57514.42504487384 47763.15810092928 51939.68156344451 59174.06450481851 46656.85280995289 52761.72741269353 55105.19562868262 54287.45901250418 0.6750437937902563 0.6086015419728624 1.059442200667863 0.8798193720934306 0.9567528579939816 1.090013523955667 0.8594407190656371 0.971895321174284 1.0150630851222948 1.0 15.728331337981935 -5.255857041255442 24.9997252534096 0.9734001102466653 0.6418226313599938 0.792152089495693 0.06904787272961375 185.18981407803284 829340.659485176 0.017228698075413468 0.042971137467488846 5.5480831174803845e-06 5.255857041255442 -0.33157747888667144 EQTLSPT(ph)ITSGLHNIAR ddPTM_PC-9_Lapatinib_30min_R1 1 EQTLSPTITSGLHNIAR 17 0 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;H7BXG7;O94979-7;O94979-6;O94979-10;O94979-4;H0Y8W8 D6REX3 SEC31A Protein transport protein Sec31A 1 EQT(0.003)LS(0.023)PT(0.964)IT(0.009)SGLHNIAR 192.72 3.621e-09 6567800.0 20472.0 20492.0 26040.0 21683.0 23970.0 28284.0 19554.0 19875.0 26434.0 16430.0 True False 20180.065525895 20444.55203302474 23899.091717306845 23277.6401523676 22560.131726833173 27074.3592532243 20566.41044154319 20798.465057254685 23456.724557639645 19269.903608401135 1.047232302557915 1.060957669975655 1.2402289187833568 1.207979065459321 1.1707443994165903 1.405007508258663 1.0672814384279958 1.0793237724441518 1.2172725424227433 1.0 14.23406173457543 -10.245985711417655 0.6719318979529092 0.9765019918742276 1.1705576715489439 0.18129252856782208 0.10486336179283352 38.51550031645512 11.239322446088755 2.1917157025309035 0.040836029303963406 5.6756327831730124e-11 10.245985711417655 0.19405567967471626 EQTVSET(ph)LGPGGEAVR ddPTM_PC-9_AZD4547_30min_R2 1 EQTVSETLGPGGEAVR 16 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 EQT(0.282)VS(0.141)ET(0.577)LGPGGEAVR 177.12 3.8709e-29 0.0 28239.0 31331.0 31821.0 44803.0 41702.0 30418.0 29956.0 38911.0 27476.0 35868.0 True False 37218.41459231106 41458.13303890162 31399.032748527963 34474.36054944981 35912.397128917284 28515.957651432003 32622.02596753852 32898.199035827565 28928.32526663428 34612.27223736951 1.0752953269600083 1.1977870957036132 0.90716473432298 0.996015526314658 1.037562540899701 0.823868408750248 0.9424988265381146 0.9504778770435266 0.835782322184601 1.0 15.078996034661015 -5.267000863811668 24.922721356221313 0.9368047775336138 1.1365412162502686 0.5649914010412279 0.07015117302807762 275.3670197386831 1234009.412267291 0.01816246513571499 0.03954239743485781 5.407532473863727e-06 5.267000863811668 0.1997364387166548 EQTVSET(ph)LGPGGEAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EQTVSETLGPGGEAVR 16 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 EQT(0.025)VS(0.005)ET(0.97)LGPGGEAVR 174.87 1.0786e-22 0.0 28543.0 24294.0 27703.0 29105.0 32748.0 37438.0 25849.0 37012.0 23545.0 17194.0 True False 33374.76615005288 26705.74776654733 28363.544584212563 27474.341209683123 26331.264483485003 35474.68537416767 23400.395589446303 36040.47421745556 23889.301082236227 20311.13609237088 1.643175743506975 1.314832791484192 1.3964528845270388 1.3526737787948175 1.2963954533973783 1.7465633243180525 1.1520968341222324 1.774419414726526 1.1761676438773578 1.0 14.30998331780436 -8.515261287193283 24.09234943122017 0.9999999619406402 1.4449822921358035 0.38522380222869346 0.19350332777516083 272.45946071451823 861727.7581943551 0.17116499788764078 0.044194612427373846 3.0530837154858467e-09 8.515261287193283 0.4449823301951633 EQVANS(ph)AFVER ddPTM_PC-9_AZD4547_30min_R2 2 EQVANSAFVER 11 0 P08238;Q58FF7 P08238 HSP90AB1;HSP90AB3P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 1 EQVANS(1)AFVER;EQVANS(1)AFVER 124.16 0.00052534 7509300.0 18917.9 17987.6 23138.0 40324.0 26351.0 28271.0 16971.300000000003 34168.0 17559.199999999997 21765.0 True False 24933.398683235297 23801.739933310342 22831.175001899377 31027.924799589604 22692.61850136922 26503.209900836137 18481.712822235495 28888.12070253032 18487.343464182723 21003.013974750396 1.1871343185892258 1.1332535397978853 1.0870427943983076 1.4773082014272356 1.080445812617658 1.2618765065193984 0.8799552694891322 1.37542739043355 0.8802233568195504 1.0 14.358308751937027 -7.207003869056036 24.999912774736767 1.0651856102174577 1.2026924583053418 0.18984655879488643 0.16772597111965934 616.8288583274758 283283.07220873126 0.06100716106706869 0.04725591958710926 6.20863503037556e-08 7.207003869056036 0.13750684808788405 EQVANS(ph)AFVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EQVANSAFVER 11 0 P08238;Q58FF7 P08238 HSP90AB1;HSP90AB3P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 1 EQVANS(1)AFVER;EQVANS(1)AFVER 113.59 0.0026747 0.0 18185.6 19471.3 21178.5 19757.0 27855.0 25385.0 25315.0 17480.3 19400.1 15395.0 True False 21264.0628980276 21404.281982661287 21683.475759908524 18650.07934305823 22397.0127087906 24053.76591226151 22916.979935271505 17021.460646908803 19683.789761116634 18185.99163324705 1.1692550687834542 1.1769653486219944 1.1923174824444265 1.0255189664204372 1.2315530085170114 1.3226535235113155 1.2601446430545704 0.9359654942208767 1.08235999213435 1.0 14.150539973770977 -7.760277117085829 24.999998998674524 1.0068720448960613 1.195547407140498 0.5507403890021779 0.07896537448034115 25.448467157702716 547432.5693959462 0.04275726243518809 0.022906255943173692 1.7366923166422255e-08 7.760277117085829 0.1886753622444366 EQVANS(ph)AFVER ddPTM_PC-9_Lapatinib_30min_R1 2 EQVANSAFVER 11 0 P08238;Q58FF7 P08238 HSP90AB1;HSP90AB3P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 1 EQVANS(1)AFVER;EQVANS(1)AFVER 130.47 0.00020762 7559500.0 32614.0 26450.0 36625.0 25142.0 27301.0 32308.0 27016.0 27860.0 31640.0 16555.5 True False 32148.918379324885 26388.75665008314 33613.83387658845 26991.026551253344 25695.208855831163 30926.262153626438 28414.756289696776 29154.477307930352 28076.37001602928 19417.096116182896 1.6557016655302457 1.3590475368811619 1.7311462885829507 1.3900650431841899 1.3233291271816832 1.5927336388808104 1.4633885581899608 1.5014849354137965 1.445961324393375 1.0 14.24503983715328 -12.365107124813056 0.34662982744256926 1.6550361338647076e-14 1.5139435691630168 0.601945225899148 0.12215150665344837 52.75837000956744 1.7467277565528212 38.995356511786724 0.09351865112818623 4.3141264973362607e-13 12.365107124813056 1.513943569163 EQVQSGLR ddPTM_PC-9_Lapatinib_30min_R1 2 EQVQSGLR 8 0 A0A087X211;Q8TCG1-2;Q8TCG1 A0A087X211 KIAA1524 Protein CIP2A 0 ; 70.525 0.031810000000000005 22049000.0 89519.0 71192.0 90214.0 71313.0 75696.0 72822.0 70873.0 62723.0 84942.0 54947.0 False True 88242.44264422591 71027.15929802357 82796.95315611069 76557.59591319431 71243.71010406196 69707.57281637326 74542.45715574766 65637.33956156908 75374.9374810859 64444.51573772471 1.369277767612587 1.1021443560393689 1.284778886276009 1.1879613809927168 1.1055046234501709 1.081668036735167 1.1566920210731257 1.0185093147211923 1.1696098049343042 1.0 15.975769969251338 -1.522878745298448 0.19712721632407967 1.021906036699885 2.299382139978162 0.528132557871023 0.0742359080621246 43.35261485511212 0.5190004465284243 0.13427969393290806 17.03033605391982 0.029999999998748975 1.522878745298448 1.277476103278277 EQVTAT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 EQVTATPR 8 0 Q8IYA6-2;Q8IYA6-3;Q8IYA6 Q8IYA6-2 CKAP2L Cytoskeleton-associated protein 2-like 1 EQVTAT(1)PR 95.775 0.015461 19715000.0 5640.4 7358.7 7773.4 9104.5 9421.6 6538.8 5538.4 8124.6 10002.0 6082.3 True False 7433.9298723917755 9737.255867778409 7670.319636950666 7005.598188122792 8113.573468653947 6129.927802327024 6031.306870697532 6869.129754734773 10530.685300512305 5869.360528308036 1.266565554550243 1.6589977427379765 1.306840770805707 1.1935879819163706 1.3823607238850009 1.0443944911481016 1.0275918205413392 1.1703369935455201 1.7941793232367669 1.0 12.518987613739503 -5.507050363661702 20.03819349085107 1.22932539877737 1.4678165539696015 0.13285217499015456 0.23489886965055554 96.50063208273983 122161.07958772196 0.06166720762217752 0.12166306757169648 3.1113555028131564e-06 5.507050363661702 0.23849115519223152 EQWIQDAEECDR ddPTM_PC-9_AZD4547_30min_R2 2 EQWIQDAEECDR 12 0 O94906-2;O94906 O94906-2 PRPF6 Pre-mRNA-processing factor 6 0 ; 172.13 0.00038157 4038600.0 15789.2 14628.5 23836.4 34524.0 27781.7 26463.7 22141.5 26455.7 20619.8 23478.3 False True 20809.83716423805 19356.876549091074 23520.313761572907 26565.02519048288 23924.69050204884 24808.920655539514 24112.050606230954 22367.57945650701 21709.720531843974 22656.331863238334 0.9184998388023984 0.8543693950960842 1.038134235654292 1.172521013147177 1.0559825238466125 1.0950104723613237 1.064252181323078 0.987255112236423 0.9582186853057926 1.0 14.467626682407401 -5.299270880428536 7.309557427820863 1.0535099880497774 0.886490700025012 0.5397734364196729 0.058823632627938695 0.1622678513973864 27.06277648920936 0.016497983656846092 0.03525960529904381 5.0202936346546985e-06 5.299270880428536 -0.1670192880247654 EQWIQDAEECDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EQWIQDAEECDR 12 0 O94906-2;O94906 O94906-2 PRPF6 Pre-mRNA-processing factor 6 0 ; 159.44 0.00025139 1021100.0 8593.900000000001 8897.6 11585.7 11482.4 12965.2 10634.1 12940.0 13377.400000000001 10104.3 9431.0 False True 10048.677532737964 9780.89492581015 11861.947027011927 10839.07835444307 10424.762131466947 10076.42907573685 11714.229522512862 13026.257424526913 10252.056272042448 11140.765644245073 0.9019736931571446 0.87793740916385 1.0647335565432516 0.9729204168334836 0.9357312113330389 0.9044646838022286 1.0514743686906312 1.1692425673863645 0.9202290578061211 1.0 13.443560764220061 -7.276445380541015 23.765828195175878 1.0493400691076356 0.9465729791385067 0.2564015557630114 0.07532062313449923 559.706414953956 886432.5406533199 0.03158153108827041 0.02140402745029891 5.29120538373443e-08 7.276445380541015 -0.10276708996912887 EQWIQDAEECDR ddPTM_PC-9_Lapatinib_30min_R1 2 EQWIQDAEECDR 12 0 O94906-2;O94906 O94906-2 PRPF6 Pre-mRNA-processing factor 6 0 ; 114.82 0.0034617 3178900.0 8703.8 14751.1 13811.4 10620.099999999999 11339.0 10931.400000000001 9091.3 12000.2 12694.7 11254.7 False True 8579.682215918561 14716.944734254881 12675.880005545758 11401.137581615052 10672.062313331724 10463.88950433801 9562.003029927459 12557.773100883916 11264.889204882656 13200.059899054906 0.6499729759963322 1.1149149963560832 0.9602895822051021 0.8637186246731613 0.8084859004386654 0.7927153046545797 0.7243908817877467 0.9513421300295026 0.8533968247893479 1.0 13.688256855790254 -4.673375101922981 22.976956400861457 0.8846469803801933 0.6498919855375402 0.31204017708175524 0.10855793680272958 118027.74486574312 30765521.08500944 0.028436608908666745 1382.121343276226 2.1214113987871907e-05 4.673375101922981 -0.23475499484265305 EQYGLGPYEAVT(ph)PLTK ddPTM_PC-9_AZD4547_30min_R2 4 EQYGLGPYEAVTPLTK 16 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 EQYGLGPY(0.104)EAVT(0.894)PLT(0.002)K;EQYGLGPYEAVT(0.998)PLT(0.002)K;EQYGLGPYEAVT(1)PLTK;EQYGLGPY(0.001)EAVT(0.752)PLT(0.248)K 147.1 7.3421e-05 32855100.0 98595.0 107137.0 131095.0 178054.0 168861.0 157013.0 126508.0 162222.0 133115.0 148235.0 True False 129946.15909660104 141766.9400717755 129356.59464404882 137006.4012068775 145417.56490302886 147194.95228891747 137766.96692153031 137154.31739071285 140151.1871403413 143045.3377692224 0.9084263851104711 0.9910629894173177 0.9043048634884007 0.9577830591578761 1.0165837431041174 1.0290090861010075 0.9631000147924585 0.958817110222679 0.9797675990422682 1.0 17.12611295156779 -6.008925078306818 24.619353229721334 0.989414806794135 0.9387111329127487 0.4210227481449582 0.029968874695020846 383.57897958611807 1058088.2623651568 0.008872668066120729 0.012410801143848866 9.796589753027498e-07 6.008925078306818 -0.0507036738813863 EQYGLGPYEAVT(ph)PLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EQYGLGPYEAVTPLTK 16 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 EQYGLGPYEAVT(0.947)PLT(0.053)K;EQYGLGPYEAVT(0.5)PLT(0.5)K;EQYGLGPYEAVT(0.61)PLT(0.39)K;EQYGLGPYEAVT(0.7)PLT(0.3)K 200.94 5.541000000000001e-12 26593400.0 97674.0 118190.0 117907.0 132984.0 153481.0 131658.0 133803.0 129272.0 114643.0 98433.0 True False 114208.27905056464 129923.12210950161 120718.35004478753 125533.3376199453 123407.49982257755 124753.62270933713 121128.2111901689 125878.74697500587 116319.43699175236 116278.12370480095 0.9821991911437177 1.1173479410395515 1.0381862572125702 1.0795954872701667 1.0613131334650374 1.072889884481222 1.0417110917413928 1.0825660318924506 1.000355297158529 1.0 16.827220171494716 -8.274691735558967 24.04316374347006 1.0001776141654168 1.0612823611471098 0.33259812174987136 0.033521822958424666 540.2238781991173 980087.3400368029 0.02831059763011165 0.007515612613113841 5.31261402488151e-09 8.274691735558967 0.06110474698169299 EQYGLGPYEAVT(ph)PLTK ddPTM_PC-9_Lapatinib_30min_R1 3 EQYGLGPYEAVTPLTK 16 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 EQYGLGPYEAVT(0.999)PLT(0.001)K;EQYGLGPYEAVT(1)PLTK;EQYGLGPYEAVT(0.723)PLT(0.277)K 117.2 0.0003585 19009000.0 94263.0 94503.0 113166.0 95263.0 111932.0 119132.0 114396.0 106352.0 124248.0 92689.0 True False 92918.79233428277 94284.18410974712 103861.92831339285 102268.9588080522 105348.37982677907 114037.0020702559 120318.86513607322 111293.50217706397 110253.88185055659 108710.17014967064 0.8547387259752559 0.8672986527381751 0.9554021318373176 0.9407487695700386 0.9690756594506006 1.0490003089246511 1.1067857309984879 1.0237634806737643 1.0142002509862746 1.0 16.730127389394028 -5.798570097713768 0.827191592256365 1.0434042980929503 0.8436437060924128 0.7865107820173085 0.03424825368177637 0.38811075902865316 0.48537448453731097 0.01700817828144954 0.05467586111197293 1.590120008276759e-06 5.798570097713768 -0.19976059200053753 EQYVPPRS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 8 EQYVPPRSPK 10 1 Q71RC2-5;Q71RC2-3;Q71RC2;Q71RC2-4;X6RLN4;Q71RC2-2;Q71RC2-6 Q71RC2-5 LARP4 La-related protein 4 1 EQYVPPRS(1)PK;EQYVPPRS(1)PK;EQYVPPRS(1)PK;EQYVPPRS(1)PK;EQYVPPRS(1)PK;EQYVPPRS(1)PK;EQY(0.005)VPPRS(0.995)PK;EQYVPPRS(1)PK 118.61 0.0011637000000000002 327078800.0 648548.0 602914.0 636995.0 753540.0 705959.0 707891.0 674096.0 691377.0 654125.0 711499.0 True False 854772.7733635802 797794.1598741284 628548.0300948615 579822.9950769462 607948.7785893551 663626.4638644818 734089.2381030126 584540.5709129382 688700.7120773449 686589.6365734418 1.2449543771582234 1.1619665042654508 0.9154639053856856 0.844497155492566 0.8854616297785106 0.9665547344647347 1.0691819377971195 0.8513681823544568 1.0030747267238678 1.0 19.3890885557679 -5.1630816001560245 3.82145938996916 0.9363929648601292 1.226925434536258 0.7041417845265855 0.06844807121051842 0.12496166314867828 3.2659415691339553 0.018443996766807007 0.05686657243504457 6.869393579569699e-06 5.1630816001560245 0.29053246967612867 EQYVPPRS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 EQYVPPRSPK 10 1 Q71RC2-5;Q71RC2-3;Q71RC2;Q71RC2-4;X6RLN4;Q71RC2-2;Q71RC2-6 Q71RC2-5 LARP4 La-related protein 4 1 EQYVPPRS(1)PK;EQYVPPRS(1)PK;EQYVPPRS(1)PK;EQYVPPRS(1)PK;EQYVPPRS(1)PK;EQYVPPRS(1)PK;EQYVPPRS(1)PK;EQY(0.001)VPPRS(0.999)PK 120.84 0.003246 246143000.0 546207.0 581447.0 479573.0 664806.0 638599.0 554203.0 683352.0 670746.0 558646.0 484915.0 True False 638669.0570200031 639169.2155106477 491007.83911073033 627559.0751501314 513470.11017127795 525139.6190613775 618619.9515199534 653139.6282141313 566815.1408956015 572826.2509149712 1.1149437652339809 1.1158169069411665 0.8571671398202283 1.0955487360220237 0.8963802014155529 0.9167520137608494 1.0799434392747125 1.1402054762170486 0.9895062246016689 1.0 19.127738082955624 -10.145801062033332 12.67880539227742 0.9999999909774773 1.021194283038626 0.004658754128886167 0.09761244687434008 0.0 0.0 0.09690628768837445 0.023503227054450602 7.148236915209601e-11 10.145801062033332 0.021194292061148756 EQYVPPRS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 6 EQYVPPRSPK 10 1 Q71RC2-5;Q71RC2-3;Q71RC2;Q71RC2-4;X6RLN4;Q71RC2-2;Q71RC2-6 Q71RC2-5 LARP4 La-related protein 4 1 EQY(0.004)VPPRS(0.996)PK;EQYVPPRS(1)PK;EQYVPPRS(1)PK;EQYVPPRS(1)PK;EQYVPPRS(1)PK;EQYVPPRS(1)PK 89.82700000000001 0.0042941 269870000.0 597469.0 610388.0 560953.0 616037.0 619442.0 604651.0 587866.0 612683.0 575758.0 531674.0 True False 588948.9824976055 608974.6840881282 514833.6096811999 661342.416019188 583007.6394298287 578791.486240324 618302.8250295708 641150.4888892556 510910.0710394747 623573.1424889264 0.9444745810361199 0.9765890199463529 0.8256186397417564 1.0605691152436578 0.934946680196673 0.928185399278325 0.9915481968349059 1.0281881068998113 0.8193266133949115 1.0 19.250199266435864 -5.7621857370219045 24.99999946750386 0.9654650154831865 0.9216636036061284 0.0928707190765018 0.07161797258434782 56.21563461289508 1883112.283774924 0.019255298579720366 0.030552767021243408 1.729076717662925e-06 5.7621857370219045 -0.043801411877058105 ERAS(ph)SPPDRIDIFGR ddPTM_PC-9_AZD4547_30min_R2 1 ERASSPPDRIDIFGR 15 2 Q9NWB6-2;Q9NWB6 Q9NWB6-2 ARGLU1 Arginine and glutamate-rich protein 1 1 ERAS(0.5)S(0.5)PPDRIDIFGR 66.78399999999999 0.009962899999999998 1373000.0 3482.3 2474.5 2384.4 4507.7 3944.6 4725.5 3355.6 4047.0 2836.5 3124.6 True False 4589.598963660359 3274.333733515114 2352.781298060717 3468.5194082707585 3396.96037875227 4430.013737978891 3654.2418993414435 3421.629140808365 2986.43159917048 3015.2087050542195 1.522149679379434 1.0859393341583745 0.7803046250552693 1.1503414017267464 1.12660870640833 1.4692229199766889 1.2119366374924727 1.1347901507026317 0.9904560152550959 1.0 11.558042149913776 -8.178520581030678 3.615480752859213 0.9924653145178494 1.1785642206012885 0.1360111524624279 0.19356726700190727 0.5626029826782443 13.304272960672064 0.1664388357665466 0.05377325756716083 6.629479301059587e-09 8.178520581030678 0.18609890608343915 ERDAEQSGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 ERDAEQSGSPR 11 1 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 ERDAEQS(0.102)GS(0.898)PR;ERDAEQS(0.047)GS(0.953)PR 123.76 0.002075 27800500.0 46279.3 40841.1 38108.8 47970.1 39430.3 45439.0 36417.9 40231.9 52366.9 62834.0 True False 60995.15473076041 54042.18688375998 37603.45241215242 36911.33457565701 33956.08346152095 42597.69214686759 39659.02254917948 34014.98429208995 55134.907424854755 60634.20078518109 1.0059529760581514 0.8912822496865138 0.6201690122935148 0.6087543679585876 0.560015354730622 0.7025357239849758 0.6540701788036445 0.560986767395525 0.9093037709887593 1.0 15.887844156499343 -10.655970942165565 11.612264140151051 0.9999711893708744 0.7099124874528572 0.2283987988914723 0.15046577795873467 1.0712701140092675e-10 0.0 0.15321521652825182 0.03716014830575666 2.208152471443155e-11 10.655970942165565 -0.2900587019180172 ERDAEQSGS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ERDAEQSGSPR 11 1 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 ERDAEQSGS(1)PR;ERDAEQS(0.002)GS(0.998)PR;ERDAEQS(0.062)GS(0.938)PR;ERDAEQS(0.133)GS(0.867)PR;ERDAEQS(0.248)GS(0.752)PR 167.03 0.005991399999999999 17969590.0 27840.2 47708.7 40063.100000000006 34183.5 67491.7 58566.2 28126.4 45801.9 56891.299999999996 65352.5 True False 32552.99599098562 52444.904440185914 41018.35624415283 32268.309319402266 54267.1858782223 55494.88537209728 25462.063774498147 44599.64865612449 57723.22763473461 77200.39091989468 0.4216687973091164 0.6793347004499529 0.5313231676082397 0.41798116479597597 0.7029392627626908 0.7188420254203162 0.3298178088362054 0.5777127307865882 0.7477064163396514 1.0 16.236320532441322 -8.54121812402966 2.4775873614317203 0.9977395474673919 0.5505006409561929 0.5703413084419127 0.1233902180545834 0.21706231189746258 3.185353038176053 0.11927784145831805 0.03240908064939358 2.8759536067161293e-09 8.54121812402966 -0.447238906511199 ERDAEQSGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 ERDAEQSGSPR 11 1 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 ERDAEQS(0.093)GS(0.907)PR 88.28200000000001 0.0046771 17895000.0 18586.0 26459.0 29909.0 25139.0 28058.0 18457.0 35726.0 36645.0 39529.0 28740.0 True False 18320.96023174504 26397.735811136106 27449.997472078718 26987.80592124563 26407.683604150407 17667.637135368448 37575.71747133946 38347.66047914959 35076.82776117643 33707.670706357196 0.5435249558282218 0.7831373470180942 0.8143546230532538 0.8006428612747717 0.7834324665800765 0.5241429254865828 1.1147527160413597 1.1376538240572436 1.0406185602899287 1.0 15.040789316082693 -7.279245384357612 24.946691656065376 1.0847274686992405 0.7240578557274506 0.7491367214165038 0.10315992209259531 417.8000850969546 585346.7210849646 0.04367836364250724 0.02951860200174227 5.257201409240488e-08 7.279245384357612 -0.3606696129717899 ERDGQS(ph)SPQPSPR ddPTM_PC-9_AZD4547_30min_R2 1 ERDGQSSPQPSPR 13 1 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 ERDGQS(0.496)S(0.496)PQPS(0.008)PR 119.62 0.0017364000000000001 0.0 1258.1 1115.9 3055.9 3372.6 3320.4 2946.9 2771.3 2595.9 3006.3 2297.5 True False 1658.1496298943518 1476.592852386145 3015.3767693104105 2595.0991761505775 2859.419774275983 2762.629877145273 3017.9403312805302 2194.763302847648 3165.2068805169097 2217.0652243045743 0.7479029537412292 0.6660123645434506 1.360075804831697 1.1705109744638122 1.2897319135808896 1.2460751478395615 1.3612320910527862 0.9899407914514912 1.4276561852210454 1.0 11.114435498438162 -5.255892761294603 24.998843047808258 1.2354699904429882 0.7069575975105714 0.6926421205091858 0.1395129138466419 218.7182415747656 985764.8462174223 0.03273352402506309 0.08155767464444251 5.5476268151215065e-06 5.255892761294603 -0.5285123929324168 ERDGQS(ph)SPQPSPR ddPTM_PC-9_Lapatinib_30min_R1 1 ERDGQSSPQPSPR 13 1 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 ERDGQS(0.5)S(0.5)PQPSPR 92.575 0.032239 0.0 2435.4 993.9 851.49 2851.0 1143.0 2303.2 1118.0 608.34 2163.0 1010.9 True False 2400.670749402337 991.5986856150342 781.4837790464513 3060.672050657196 1075.7709872244607 2204.6975050214323 1175.8845695839873 636.605697254356 1919.3801626002323 1185.6327180604205 2.024801367939306 0.8363455819920295 0.6591280479547516 2.58146726556615 0.9073391538859665 1.8595113574700455 0.9917781043590124 0.5369333078930049 1.6188657190062627 1.0 10.211441449776963 -7.327012138352123 24.690386717073494 0.9983043713144634 1.4359121333160227 0.10910990449582614 0.6065304239624246 421.80812112602143 158822.91801930146 0.24915262105254968 0.16797868443694022 4.709641629583725e-08 7.327012138352123 0.4376077620015594 ERDHS(ph)PTPSVFNS(ph)DEER ddPTM_PC-9_Lapatinib_30min_R1 1 ERDHSPTPSVFNSDEER 17 1 Q6UN15;Q6UN15-5;Q6UN15-3 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 2 ERDHS(1)PT(0.003)PS(0.126)VFNS(0.871)DEER 79.589 0.020252000000000003 7798000.0 12315.0 15495.0 11769.0 12763.0 13872.0 19076.0 13919.0 18383.0 18497.0 15630.0 True False 12139.385841705587 15459.122279509958 10801.398249653774 13701.633596119887 13056.076233401327 18260.16394832791 14639.65771380995 19237.141290440904 16413.67307795493 18331.62467433413 0.6622100363369202 0.8433034471382166 0.5892220925064363 0.7474314928181662 0.7122159909634725 0.996101778905267 0.7986012136887543 1.049396419149612 0.8953747073457979 1.0 14.16204703262502 -6.753190503504952 24.99495470436938 0.9416512524980206 0.7135058544009358 0.6465206964171947 0.0875562958281289 115.16698141107432 348967.4830023423 0.027591459780565417 0.027148114908274044 1.7652633171395577e-07 6.753190503504952 -0.22814539809708478 ERDHS(ph)PTPSVFNSDEER ddPTM_PC-9_AZD4547_30min_R2 1 ERDHSPTPSVFNSDEER 17 1 Q6UN15;Q6UN15-5;Q6UN15-3 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 ERDHS(0.751)PT(0.248)PS(0.001)VFNSDEER 82.367 0.0018964000000000001 12965000.0 51074.0 54257.0 55683.0 64932.0 55268.0 72572.0 67173.0 68950.0 53529.0 55286.0 True False 67314.46959480485 71794.51419653645 54944.60703737413 49962.930589399686 47594.99219512256 68034.0613676023 73151.26686865602 58295.361813377036 56358.433658380636 53350.45396774875 1.2617412709458402 1.3457151506140406 1.029880777970307 0.9365043195246872 0.8921197226155665 1.2752292868722364 1.3711460995791562 1.0926872683898354 1.0563815200607338 1.0 15.703212926779718 -2.3250124245608452 0.014391379169158332 1.713576482734088e-07 2.442896115860614 0.07947854468644444 0.15786946857348352 20527.60187594377 26.16620194571651 1840.8288341356595 2670.305747560054 0.004731377229559334 2.3250124245608452 2.442895944502966 ERDHS(ph)PTPSVFNSDEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ERDHSPTPSVFNSDEER 17 1 Q6UN15;Q6UN15-5;Q6UN15-3 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 ERDHS(0.692)PT(0.176)PS(0.131)VFNSDEER;ERDHS(0.492)PT(0.492)PS(0.016)VFNSDEER 63.302 0.010931 29379000.0 62028.0 78491.0 86540.0 73370.0 97173.0 89582.0 89485.0 73753.0 73985.0 65726.0 True False 72528.11529115641 86283.06775105245 88603.4418047778 69259.31676874925 78132.64821221713 84884.16221990196 81008.33298470374 71817.06189776292 75066.89065913121 77641.60351327014 0.9341398426780334 1.1112994045300129 1.1411851094707763 0.8920387219580257 1.0063245048624359 1.09328193106411 1.043362441256873 0.9249816934227574 0.9668384894485227 1.0 16.24454229354067 -7.748881291670127 24.875623842710223 0.9594325676727821 1.0349625314149067 0.14747457686013432 0.07408256511731581 372.86049840481564 738582.463328996 0.036256489771493546 0.020750153403886428 1.7828660223748598e-08 7.748881291670127 0.07552996374212462 ERDHS(ph)PTPSVFNSDEER ddPTM_PC-9_Lapatinib_30min_R1 2 ERDHSPTPSVFNSDEER 17 1 Q6UN15;Q6UN15-5;Q6UN15-3 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 ERDHS(0.836)PT(0.157)PS(0.006)VFNS(0.001)DEER;ERDHS(0.821)PT(0.175)PS(0.004)VFNSDEER 72.968 0.0047616 41240000.0 118114.0 128512.0 122268.0 133319.0 140467.0 116114.0 136494.0 149967.0 118568.0 127089.0 True False 116429.67270054507 128214.43835975374 112215.59700812865 143123.72399914634 132205.00722874733 111148.07489495412 143560.99144972887 156935.01430144985 105213.62326360807 149056.1643145523 0.7811127653522886 0.8601753503409869 0.7528410349492207 0.9601999666187119 0.8869476001660416 0.7456791566191051 0.9631335417082987 1.0528582633474377 0.7058656295594485 1.0 17.185496514590717 -1.5228787655048006 0.05989551509770091 1.1509227799713933 0.2969456561583088 0.15398568768047516 0.10549395609358778 645.1055977772139 2.8982098458056393 8.398765639855004 48.1287506762948 0.02999999860294362 1.5228787655048006 -0.8539771238130844 ERDHS(ph)PTPSVFNSDEERYR ddPTM_PC-9_Lapatinib_30min_R1 1 ERDHSPTPSVFNSDEERYR 19 2 Q6UN15;Q6UN15-5;Q6UN15-3 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 ERDHS(0.637)PT(0.297)PS(0.064)VFNS(0.002)DEERY(0.001)R 42.903999999999996 0.036131 8668800.0 13676.0 5620.0 13684.0 9679.4 7865.7 10592.0 4903.4 7752.4 12179.0 5074.4 True False 13480.97773212876 5606.98723529177 12558.95434176754 10391.25536553184 7403.05499056119 10139.004851157959 5157.274059479536 8112.604805527614 10807.2727694444 5951.503278787018 2.265138251738699 0.9421127692690335 2.110215478924712 1.7459883459309282 1.243896649935143 1.7036040099812229 0.8665498140380166 1.3631185980260525 1.8158895766662573 1.0 12.5390384066835 -6.252506420510547 22.389864598303703 1.3456224172447218 1.7316210290173566 0.20200233800730816 0.41957429318048955 291.4172309173311 730412.6024356518 0.12018238097676189 0.1523513188744689 5.591052618248163e-07 6.252506420510547 0.38599861177263484 ERDHSPT(ph)PSVFNSDEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ERDHSPTPSVFNSDEER 17 1 Q6UN15;Q6UN15-5;Q6UN15-3 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 ERDHS(0.368)PT(0.632)PSVFNSDEER 92.8 0.0012380000000000002 14097000.0 36117.0 44265.0 41978.0 40884.0 50291.0 37452.0 42483.0 33233.0 34724.0 32816.0 True False 42230.89475673409 48659.336662806396 42978.914722451555 38593.40202771639 40436.83956696419 35487.95118952208 38458.70268971516 32360.668963274118 35231.77280864602 38765.281028686935 1.089399938194245 1.2552298183211337 1.1086960698323447 0.9955661613585787 1.043119990205676 0.9154570855106253 0.9920914196715122 0.8347848410882588 0.9088486365563541 1.0 15.24247750331865 -5.996228357913077 0.95022838923902 0.9200446368833074 1.1862272308723163 0.6640702500151865 0.06546920570343007 0.3427158981247048 0.6262306195080577 0.0280181383785977 0.06214855279423094 1.0087223467521072e-06 5.996228357913077 0.2661825939890089 ERDQGGFGDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ERDQGGFGDR 10 1 A0A087WTP3;Q92945;M0R0I5 A0A087WTP3 KHSRP Far upstream element-binding protein 2 0 87.789 0.013484999999999999 2513500.0 6996.7 8856.5 10646.0 7673.0 9780.8 9135.2 7037.8 6430.1 5869.9 5899.6 False True 8181.10311887591 9735.714789430584 10899.841015179827 7243.106686201634 7864.322452060282 8656.134030399493 6371.12863474042 6261.316688254108 5955.736182740218 6969.150778792094 1.1739024421414332 1.396972902216071 1.5640127988548138 1.0393097977221586 1.1284477408628173 1.2420643928010682 0.9141900981864933 0.8984332362714832 0.8545856406011749 1.0 12.766767152826345 -6.761197426646469 0.8080877650212418 0.8911231805347233 1.352987821571023 0.581478891380611 0.14092564615541722 0.4526081846634359 0.6460357999687222 0.0981362114181635 0.09387753945534319 1.7330160040498628e-07 6.761197426646469 0.46186464103629965 ERDSELS(ph)DTDSGCCLGQSESDK ddPTM_PC-9_Lapatinib_30min_R1 2 ERDSELSDTDSGCCLGQSESDK 22 1 A0A087WTW0;A0A087WVR3;Q96T88;Q96T88-2 A0A087WTW0 UHRF1 E3 ubiquitin-protein ligase UHRF1 1 ERDS(0.215)ELS(0.73)DT(0.033)DS(0.022)GCCLGQSESDK;ERDS(0.175)ELS(0.666)DT(0.131)DS(0.027)GCCLGQSESDK 97.12799999999999 6.6265e-05 42153000.0 39344.0 67738.0 66868.0 66669.0 75730.0 65644.0 75818.0 75038.0 63847.0 60824.0 True False 38782.947345194036 67581.1568228102 61370.37115794446 71572.0606612643 71275.71029090857 62836.55914363798 79743.4850596769 78524.53941968692 56655.87852128386 71337.34735711444 0.5436555854964269 0.9473460862582853 0.8602838966064249 1.0032901882792877 0.9991359775981391 0.8808367772504694 1.117836421089242 1.1007493596109401 0.7941965971577943 1.0 16.122369950472102 -4.459532784917418 1.7267540316372256 0.980377985970155 7.924958331383587e-15 0.6250072848545029 0.09769011609079957 1.6611449702697434 2.4179299670291368 0.026459185530938057 3.525278541421754 3.4711007153776297e-05 4.459532784917418 -0.9803779859701471 ERDY(ph)AEIQDFHR ddPTM_PC-9_AZD4547_30min_R2 1 ERDYAEIQDFHR 12 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-5 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 ERDY(1)AEIQDFHR 104.24 0.0023967 1648500.0 9739.4 9015.5 11206.0 13673.0 14657.0 13910.0 8277.5 12003.0 9044.4 8735.7 True False 12836.326607895278 11929.584067288552 11057.401118129668 10520.901095744191 12622.128548236073 13040.205501065779 9014.181464357727 10148.212151500564 9522.468519491444 8429.865801940143 1.5227201606152478 1.4151570555895379 1.3116936114908015 1.248050840064713 1.4973107336217708 1.5469054677079868 1.0693149423900798 1.2038402970976052 1.1296109265819911 1.0 13.041293949231996 -7.271711584349015 24.999999984369083 1.1176782157836411 1.4135329940698773 0.7167086622484176 0.09911634310831795 454.2113871257399 1105433.52018998 0.044041410776949994 0.030063285205382137 5.3491948233768147e-08 7.271711584349015 0.2958547782862362 EREAELGAR ddPTM_PC-9_Lapatinib_30min_R1 1 EREAELGAR 9 1 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YAR2;H0YBN4;Q9H361;Q4VXU2;Q4VXU2-2 A0A087WTT1 PABPC1;PABPC3;PABPC1L Polyadenylate-binding protein;Polyadenylate-binding protein 1;Polyadenylate-binding protein 3;Polyadenylate-binding protein 1-like 0 92.051 0.009498000000000001 2402300.0 12970.0 7260.8 10353.0 8151.6 10066.0 9765.1 8028.9 6306.1 13239.0 7034.3 False True 12785.045421593295 7243.988063702222 9501.8163037357 8751.095856940447 9473.937670517438 9347.469436559917 8444.597156290583 6599.1044275498825 11747.884407149559 8250.169382384422 1.5496706587493392 0.8780411320002016 1.15171166352339 1.06071711395715 1.1483325046326902 1.133003336454937 1.0235665190488452 0.7998750233710527 1.4239567532071984 1.0 13.010208023974174 -4.746954365081555 24.99614140658965 1.067963081745068 1.5496719039395954 0.4455040733570246 0.1609406654102739 694.7823724709464 1198887.4268351654 0.03756728178856904 0.8083408464016366 1.7907940177096284e-05 4.746954365081555 0.4817088221945274 ERECS(ph)PSSPLPPLPEDEEGSEVTNSK ddPTM_PC-9_AZD4547_30min_R2 3 ERECSPSSPLPPLPEDEEGSEVTNSK 26 1 Q96GY3 Q96GY3 LIN37 Protein lin-37 homolog 1 ERECS(0.504)PS(0.248)S(0.248)PLPPLPEDEEGSEVTNSK;ERECS(0.333)PS(0.333)S(0.333)PLPPLPEDEEGSEVTNSK;ERECS(0.333)PS(0.333)S(0.333)PLPPLPEDEEGSEVTNSK 84.93299999999999 6.4273e-07 33128200.0 63103.0 60992.0 83985.0 109360.0 101065.0 89713.0 84788.0 100156.0 81136.0 84502.0 True False 83168.44137606169 80706.4712364331 82871.30402517586 84148.74159515723 87033.86925888529 84103.23192790165 92333.96774387964 84679.19155591863 85424.68331757317 81543.61070040692 1.0199259103404734 0.9897338435619502 1.0162820031313908 1.03194770102003 1.0673291078396039 1.031389598835632 1.132326211100913 1.0384528086085358 1.0475950547667727 1.0 16.315284219430126 -5.917564442678859 2.17217244262852 1.0578011527351046 1.004916685890854 0.2605107400014013 0.03274500748031563 0.36891501027665463 3.5323356682745333 0.009977856209297175 0.016644832815978144 1.2090257686438923e-06 5.917564442678859 -0.05288446684425052 ERECS(ph)PSSPLPPLPEDEEGSEVTNSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ERECSPSSPLPPLPEDEEGSEVTNSK 26 1 Q96GY3 Q96GY3 LIN37 Protein lin-37 homolog 1 ERECS(0.829)PS(0.101)S(0.07)PLPPLPEDEEGSEVTNSK;ERECS(0.447)PS(0.277)S(0.277)PLPPLPEDEEGSEVTNSK 85.242 6.2052e-07 12037300.0 30602.0 30432.0 25439.0 32824.0 41348.0 31536.0 32391.0 33785.0 30451.0 26038.0 True False 35782.314182949165 33453.08784191853 26045.562237944756 30984.97769684382 33246.15621910156 29882.196644044852 29322.68998946786 32898.179548166445 30896.288267367825 30758.483283305428 1.1633315548549978 1.0876052480804745 0.8467765461010663 1.0073636405102369 1.0808776204237076 0.9715107331141978 0.9533204130836691 1.0695644269957343 1.0044802268952315 1.0 14.908696744565624 -5.009313640885465 23.31590298744425 0.9939566440514617 1.1444002030463631 0.4514204150568537 0.061460807010502744 158.2724439208307 396241.98423564143 0.015755707521261545 0.050252884825339725 9.787828679680978e-06 5.009313640885465 0.15044355899490147 ERECS(ph)PSSPLPPLPEDEEGSEVTNSK ddPTM_PC-9_Lapatinib_30min_R1 3 ERECSPSSPLPPLPEDEEGSEVTNSK 26 1 Q96GY3 Q96GY3 LIN37 Protein lin-37 homolog 1 ERECS(0.594)PS(0.203)S(0.203)PLPPLPEDEEGSEVTNSK;ERECS(0.386)PS(0.386)S(0.228)PLPPLPEDEEGSEVTNSK;ERECS(0.598)PS(0.201)S(0.201)PLPPLPEDEEGSEVTNSK 135.47 1.6161999999999998e-10 41309200.0 91666.0 98169.0 113198.0 97227.0 106940.0 111233.0 95181.0 93537.0 103870.0 93556.0 True False 90358.82603051455 97941.69571198539 103891.29739691646 104377.39791976397 100649.9994521293 106475.82388678753 100109.00645579024 97883.0704936068 92171.06680040968 109727.02994446625 0.823487394821913 0.8925940651228278 0.9468159071606759 0.9512459962927113 0.9172762582115737 0.9703700532191185 0.9123459051653565 0.8920597827458396 0.8400032958794037 1.0 16.74355943466604 -4.843966006564068 2.995147058415055 0.9260683147792325 0.8138641593597892 0.37101774093496886 0.041706711416194406 0.37128632013052404 5.2565679540799 0.01085117039303601 0.0938056977779013 1.4323000049875902e-05 4.843966006564068 -0.11220415541944329 ERECSPS(ph)SPLPPLPEDEEGSEVTNSK ddPTM_PC-9_AZD4547_30min_R2 1 ERECSPSSPLPPLPEDEEGSEVTNSK 26 1 Q96GY3 Q96GY3 LIN37 Protein lin-37 homolog 1 ERECS(0.067)PS(0.466)S(0.466)PLPPLPEDEEGSEVTNSK 84.221 6.937899999999999e-07 21469000.0 14173.0 14513.0 15030.0 21868.0 19673.0 18143.0 16039.0 20928.0 18525.0 20894.0 True False 18679.719183286412 19204.043432816667 14830.692379572465 16826.67045723206 16941.743530698513 17008.515341900536 17466.4399283399 17694.05847759759 19504.19368046295 20162.50741963864 0.9264581430527848 0.9524630559645367 0.7355579378548477 0.8345524744031877 0.8402597543099701 0.8435714362259299 0.8662831246537956 0.877572323190481 0.9673496095761145 1.0 14.299387443830499 -8.286304168643062 2.080121739749529 1.0009700714390932 0.8537408737513884 0.46120556741104013 0.054572450186184514 0.2956009795479054 2.3806007997315897 0.05421196809273449 0.015675860198362312 5.172444404080391e-09 8.286304168643062 -0.14722919768770482 ERECSPS(ph)SPLPPLPEDEEGSEVTNSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ERECSPSSPLPPLPEDEEGSEVTNSK 26 1 Q96GY3 Q96GY3 LIN37 Protein lin-37 homolog 1 ERECS(0.232)PS(0.384)S(0.384)PLPPLPEDEEGSEVTNSK;ERECS(0.283)PS(0.358)S(0.358)PLPPLPEDEEGSEVTNSK;ERECS(0.034)PS(0.483)S(0.483)PLPPLPEDEEGSEVTNSK 96.045 2.021e-09 37220900.0 85990.0 78547.0 82337.0 93198.0 107160.0 97247.0 100073.0 102769.0 90660.0 84764.0 True False 100546.4086200839 86344.62706096112 84300.22634481154 87976.41821199271 86162.76725449658 92147.1961264405 90593.36097422171 100071.42264275641 91985.73098813058 100131.04220854513 1.0041482281855578 0.8623162723217168 0.8418990203780922 0.8786128284649458 0.8605000542693192 0.9202660243416173 0.9047480079708041 0.9994045845876193 0.9186534860642904 1.0 16.61152977625973 -7.637724573862875 5.410674530451149 0.9688261991260172 0.8903384835387116 0.35191128978072406 0.047416696303805225 0.2337951738217601 10.112023425067042 0.02299123061936366 0.012951055123623541 2.3029018365855354e-08 7.637724573862875 -0.0784877155873056 EREDS(ph)GDAEAHAFK ddPTM_PC-9_AZD4547_30min_R2 1 EREDSGDAEAHAFK 14 1 Q9NPI1;Q9NPI1-2 Q9NPI1 BRD7 Bromodomain-containing protein 7 1 EREDS(1)GDAEAHAFK 71.376 0.011907 4545200.0 21338.0 20292.0 31336.0 33803.0 35015.0 31628.0 20986.0 28586.0 22632.0 23860.0 True False 28123.040142028174 26850.99216831227 30920.464165421337 26010.240601143934 30153.771652895277 29650.296160151593 22853.713344731044 24168.69054093104 23828.281315856253 23024.66866241879 1.221430829444726 1.1661836511957657 1.34292764941674 1.1296683996846495 1.309628906934618 1.2877621213523585 0.992575123655665 1.0496867900809161 1.0349022461612718 1.0 14.490892774844356 -7.263834114754964 24.999561568217324 1.0234315969211225 1.2418733336991796 0.7595940442176635 0.06161771395137306 105.94795203472118 1106022.1949249275 0.02441167647829987 0.017331105656674253 5.447106734653665e-08 7.263834114754964 0.21844173677805712 EREEGALAEPAPVPAVAHS(ph)PPATVEAATSR ddPTM_PC-9_AZD4547_30min_R2 1 EREEGALAEPAPVPAVAHSPPATVEAATSR 30 1 A6NEL2 A6NEL2 SOWAHB Ankyrin repeat domain-containing protein SOWAHB 1 EREEGALAEPAPVPAVAHS(0.955)PPAT(0.037)VEAAT(0.003)S(0.005)R 47.73 0.007491800000000001 2448000.0 4986.3 2582.7 5798.4 10912.0 5726.2 7416.1 2759.2 7626.8 5270.1 5714.6 True False 6571.839678516974 3417.5072675487922 5721.509427392744 8396.406988719422 4931.215971406797 6952.370094640828 3004.763454721332 6448.253306428768 5548.666726877611 5514.533593388865 1.1917308267730327 0.6197273458712617 1.0375327904887577 1.5225960358253163 0.8942217665186803 1.2607358313993633 0.5448807961426897 1.1693197978083405 1.0061896682485836 1.0 12.429023155798863 EREEIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EREEIEK 7 1 Q13442 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 0 91.069 0.020097999999999998 2470900.0 11932.0 16943.0 15696.0 17930.0 22251.0 22331.0 15857.0 22320.0 17966.0 19280.0 False True 13951.85193225769 18624.989067613886 16070.252167411487 16925.44022984431 17891.076280139998 21159.923048521236 14354.910165261708 21734.123649994835 18228.71876166729 22775.311379603983 0.6125866601653586 0.8177709958465444 0.7055996688503197 0.743148576445 0.7855469451961928 0.9290728322366921 0.6302838159269685 0.9542843690584374 0.8003718789105859 1.0 14.475183157956122 -14.522855173444203 0.034260446222404387 2.2453790334032155 1.1783288720758327e-06 0.433529452838723 0.09430991443203887 1062.9111463999664 2.722965065667085 148.20196620950662 52.70782472862906 3.000162832894427e-15 14.522855173444203 -2.2453778550743433 EREES(ph)EDELEEANGNNPIDIEVDQNK ddPTM_PC-9_AZD4547_30min_R2 5 EREESEDELEEANGNNPIDIEVDQNK 26 1 Q9UKL0 Q9UKL0 RCOR1 REST corepressor 1 1 EREES(1)EDELEEANGNNPIDIEVDQNK;EREES(1)EDELEEANGNNPIDIEVDQNK;EREES(1)EDELEEANGNNPIDIEVDQNK;EREES(1)EDELEEANGNNPIDIEVDQNK;EREES(1)EDELEEANGNNPIDIEVDQNK 137.67 1.2942e-12 79649600.0 130459.0 145283.0 153680.0 152259.0 143822.0 176593.0 173303.0 186898.0 178926.0 156310.0 True False 171942.2482842283 192242.88858608875 151642.10278727172 117158.03992810026 123854.79784842784 165550.6117936531 188726.63126760328 158017.20858878217 188383.6630753312 150837.6344770608 1.1399161017098622 1.2745021443260887 1.0053333394745942 0.7767162375243792 0.8211133665535143 1.097541819504136 1.2511906058584112 1.047598029076843 1.2489168484273752 1.0 17.202636905029202 -9.28214480762371 13.763711029269897 1.000000002729137 1.0665435589435068 0.016415002061924144 0.16287640213470714 0.0 0.0 0.17516363370378035 0.04248342138398165 5.222220344939042e-10 9.28214480762371 0.06654355621436991 EREES(ph)EDELEEANGNNPIDIEVDQNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 EREESEDELEEANGNNPIDIEVDQNK 26 1 Q9UKL0 Q9UKL0 RCOR1 REST corepressor 1 1 EREES(1)EDELEEANGNNPIDIEVDQNK;EREES(1)EDELEEANGNNPIDIEVDQNK;EREES(1)EDELEEANGNNPIDIEVDQNK;EREES(1)EDELEEANGNNPIDIEVDQNK;EREES(1)EDELEEANGNNPIDIEVDQNK 100.14 1.2325e-09 58092500.0 137908.0 187323.0 165111.0 179382.0 175788.0 135803.0 172907.0 141243.0 129884.0 127011.3 True False 161253.1005928421 205919.1894654216 169047.87242695433 169331.80810429025 141343.60330471647 128681.25161248175 156527.99722172617 137535.5209093286 131783.307783613 150037.44326910222 1.0747523889994834 1.3724520025050795 1.126704566164565 1.1285969982878359 0.9420555311063734 0.8576609198923983 1.0432595611548958 0.9166746507580071 0.8783361333827236 1.0 17.194963058341855 -6.067173523566018 2.055750463835195 0.9345849932473433 1.2142676423103846 0.6374892683665152 0.08777715072573256 0.1914107113870622 1.6064439087957876 0.027567204139600402 0.04131062152901979 8.566954817805201e-07 6.067173523566018 0.2796826490630413 EREES(ph)EDELEEANGNNPIDIEVDQNK ddPTM_PC-9_Lapatinib_30min_R1 5 EREESEDELEEANGNNPIDIEVDQNK 26 1 Q9UKL0 Q9UKL0 RCOR1 REST corepressor 1 1 EREES(1)EDELEEANGNNPIDIEVDQNK;EREES(1)EDELEEANGNNPIDIEVDQNK;EREES(1)EDELEEANGNNPIDIEVDQNK;EREES(1)EDELEEANGNNPIDIEVDQNK;EREES(1)EDELEEANGNNPIDIEVDQNK 124.91 3.8199e-12 72075700.0 115037.8 176181.5 170294.0 157739.5 194238.7 177000.7 180995.7 187527.0 183975.8 172252.8 True False 113397.33987665117 175773.56256130888 156293.08467384984 169340.18903354637 182813.96155397702 169430.79266978445 190366.7717272381 196240.18902097098 163254.50805293955 202026.46696757167 0.5612994256581895 0.8700521530652873 0.7736267778168752 0.8382079416392905 0.9049010473628757 0.8386564157308195 0.9422862983482005 0.9713588123702155 0.8080847549501738 1.0 17.624184783560295 -4.019074257542503 0.6963705090916825 0.9069997906459137 9.343486895167485e-40 0.6365353831957472 0.07142522381760362 5.216398337387198 0.8839184237559635 0.028121784263932765 4.76470587344285 9.57030420117927e-05 4.019074257542503 -0.9069997906459137 EREES(ph)EDELEEANGNNPIDIEVDQNKESKK ddPTM_PC-9_Lapatinib_30min_R1 2 EREESEDELEEANGNNPIDIEVDQNKESKK 30 3 Q9UKL0 Q9UKL0 RCOR1 REST corepressor 1 1 EREES(1)EDELEEANGNNPIDIEVDQNKESKK;EREES(1)EDELEEANGNNPIDIEVDQNKESKK 64.962 0.00014099999999999998 13693700.0 157036.0 33131.0 47059.0 38210.0 32109.0 35157.0 16086.9 21594.9 49765.0 25619.8 True False 154796.63784312436 33054.28720506256 43189.99067299319 41020.09086482341 30220.41174872285 33653.41706496984 16919.800968193776 22598.277890058325 44159.94165131788 30048.148293762333 5.15161987120712 1.1000440653417658 1.4373594755573993 1.3651453814656105 1.0057329141641742 1.1199830597200535 0.5630896387617383 0.7520689018547436 1.469639367444316 1.0 14.874988467666673 -4.761415080547535 9.822518436912834 1.082674513864337 5.170091754812773 0.9519820342764277 0.27363289393468115 0.015399311595110411 29.27782586223783 0.07355904094555751 0.4171052898501489 1.7321476918655168e-05 4.761415080547535 4.087417240948437 ERELEECQR ddPTM_PC-9_AZD4547_30min_R2 1 ERELEECQR 9 1 Q9UNE7;Q9UNE7-2;H3BTA3;H3BS86;H3BUD0 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 0 83.647 0.018165 4716000.0 8064.5 8227.5 10640.0 16613.0 15062.0 8200.7 8303.0 10917.0 8727.5 11940.0 False True 10628.843247979481 10886.878477468415 10498.906647947506 12783.1295182914 12970.901289044936 7687.908932608925 9041.950914957686 9230.028497703219 9188.817832455623 11521.984234253154 0.922483752093802 0.9448787861645686 0.9112064757679333 1.1094555641110015 1.1257523899819586 0.6672382791285124 0.7847564040295512 0.8010797715087745 0.7975030728768598 1.0 13.492101568413933 -6.76084590685446 24.99999982573811 0.7960980535770236 1.0003817562785717 0.47103022586035315 0.10151462133173361 14.182106048283844 597430.1278293936 0.035381722688007676 0.03337310911531482 1.734419282372448e-07 6.76084590685446 0.20428370270154816 ERELEECQR ddPTM_PC-9_Lapatinib_30min_R1 1 ERELEECQR 9 1 Q9UNE7;Q9UNE7-2;H3BTA3;H3BS86;H3BUD0 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 0 109.44 0.0030704 3799000.0 13103.0 16759.0 16275.0 13117.0 17178.0 15116.0 13862.0 17620.0 20136.0 11547.0 False True 12916.148817204084 16720.19556516989 14936.93232331677 14081.667937029266 16167.623813247412 14469.523917117036 14579.706532713082 18438.689524972466 17868.07163851979 13542.88356458965 0.95372220809575 1.2346111878926513 1.1029358889544112 1.0397835785761582 1.1938095558556396 1.068422677349915 1.0765585086203056 1.361503954237914 1.3193698043184197 1.0 13.725247331269989 -7.741081019194709 24.99439862492172 1.255327698283858 1.101888193385488 0.19976182805905474 0.11584678002052079 293.6669589313812 360541.9418477898 0.051621214998284426 0.029757815144110532 1.8151770033986164e-08 7.741081019194709 -0.15343950489836988 EREPEAASSR ddPTM_PC-9_AZD4547_30min_R2 1 EREPEAASSR 10 1 F8WC91;B9A018;Q53GS9-3;Q53GS9 F8WC91 USP39 U4/U6.U5 tri-snRNP-associated protein 2 0 84.68700000000001 0.016054 1053200.0 1263.2 2433.5 3444.0 4741.6 3127.9 2605.9 4082.5 4417.7 2250.4 4155.6 False True 1664.87132380776 3220.081285313814 3398.3303097303747 3648.4973769897338 2693.6450764841125 2442.9526610515677 4445.834591149552 3735.045973646926 2369.3515497173453 4010.113708866198 0.41516810860669545 0.8029900195085106 0.8474398873570106 0.909823920684108 0.671712891963281 0.6091978528315292 1.1086554930649455 0.9314064998677947 0.5908439814259644 1.0 11.969427430292788 -4.761341629111083 4.977409058255122 0.8297261042697872 0.38820898726495306 0.37963073888698906 0.15954037476272495 0.19439057902756268 12.569163791201497 0.04032707629047683 0.3015993396986258 1.7324406716315648e-05 4.761341629111083 -0.44151711700483415 EREPEAASSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EREPEAASSR 10 1 F8WC91;B9A018;Q53GS9-3;Q53GS9 F8WC91 USP39 U4/U6.U5 tri-snRNP-associated protein 2 0 107.45 0.0028124 729140.0 2861.4 2532.3 5056.9 6841.7 6237.2 5524.9 4815.9 6574.5 5754.8 4500.9 False True 3345.7785047738976 2783.690008612326 5177.475674400043 6458.381730090677 5015.065434114834 5235.164517969415 4359.7030879033755 6401.926341258553 5838.9530629880255 5316.8775408952015 0.62927507339403 0.5235572922643685 0.973781253109003 1.214694466896313 0.943235084039654 0.984631388950134 0.8199743278588533 1.2040763196100737 1.098192128383104 1.0 12.37636352310132 -5.3117787475629745 5.335525206873434 1.0342705756817465 0.5755578114497121 0.7163265166219767 0.11439777455449947 0.0975626455718331 6.470834891596031 0.031081597784415077 0.06849302641064214 4.877769260201272e-06 5.3117787475629745 -0.45871276423203444 EREPEAASSRGS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 1 EREPEAASSRGSPVR 15 2 F8WC91;B9A018;Q53GS9-3;Q53GS9 F8WC91 USP39 U4/U6.U5 tri-snRNP-associated protein 2 1 EREPEAAS(0.019)S(0.077)RGS(0.903)PVR 101.05 0.017922 0.0 10352.0 4916.2 8302.9 5880.4 5251.6 5547.7 3491.6 3718.1 6626.1 3464.3 True False 10204.378581675703 4904.816840950427 7620.267612120854 6312.86423243935 4942.711213042854 5310.43780332034 3672.377963469992 3890.8564995913816 5879.7988420736965 4063.099639110411 2.5114763328594827 1.2071613488721396 1.875481353883131 1.5537064785892158 1.2164878176910838 1.3069917735226955 0.9038365508245413 0.9576079459481971 1.4471214994277226 1.0 11.988365028775238 -1.5228787452806065 0.38428417461645475 1.069847899096642 18.101608672875894 0.6125010532618329 0.2898892190046188 48.27487592752132 0.6553164218976419 0.21641202015625147 614.5118507372446 0.02999999999998142 1.5228787452806065 17.03176077377925 EREQPPR ddPTM_PC-9_AZD4547_30min_R2 1 EREQPPR 7 1 Q15233;Q15233-2;H7C367;Q8WXF1-2;Q8WXF1 Q15233;Q8WXF1 NONO;PSPC1 Non-POU domain-containing octamer-binding protein;Paraspeckle component 1 0 82.671 0.028697000000000004 557830.0 450.44 652.95 2093.8 3541.0 1099.9 2283.3 1132.2 853.13 822.91 2452.1 False True 593.6705502659655 864.0033183668191 2066.0348439353843 2724.677157904643 947.197870655991 2140.5248900491374 1232.9636066379724 721.298361477104 866.4073425959389 2366.252725361152 0.25089059334326 0.36513568863822427 0.8731251830338846 1.1514734367559096 0.40029446580412237 0.9046053564386016 0.521061674191961 0.3048272712996094 0.36615165122047666 1.0 11.20838845223407 -5.095460400759284 5.7783988143534115 0.6722889518822152 0.27712457645450256 0.2377078333140682 0.27534666658885365 0.3240873537167383 15.502325989773716 0.07419640165274757 0.20761164629617013 8.02674745918136e-06 5.095460400759284 -0.3951643754277126 EREQPPR ddPTM_PC-9_Lapatinib_30min_R1 2 EREQPPR 7 1 Q15233;Q15233-2;H7C367;Q8WXF1-2;Q8WXF1 Q15233;Q8WXF1 NONO;PSPC1 Non-POU domain-containing octamer-binding protein;Paraspeckle component 1 0 ; 99.375 0.015375999999999999 1391820.0 1978.71 2485.99 2977.73 1769.51 3046.1000000000004 1716.15 1896.7800000000002 3707.79 2376.9 1873.6 False True 1950.493232549028 2480.2338428937696 2732.912533770203 1899.645668312317 2866.934386863019 1642.7542650410435 1994.9859873841813 3880.0674593528743 2109.188492133376 2197.4492635849265 0.887616958840263 1.1286876489004836 1.2436749184878653 0.8644776012772319 1.3046646556862442 0.7475732396938477 0.9078644137291954 1.7657142413485891 0.9598348990740465 1.0 11.101614140351845 EREQQIEEHR ddPTM_PC-9_AZD4547_30min_R2 2 EREQQIEEHR 10 1 Q16643-3;Q16643;Q16643-2;D6R9W4 Q16643-3 DBN1 Drebrin 0 ; 74.944 0.011347 10512500.0 23556.4 22581.7 29453.0 33825.0 34391.0 32245.0 23350.9 32479.0 25825.2 25512.1 False True 31046.8451964417 29880.792915788334 29062.433975751675 26027.16884104053 29616.403281871248 30228.715052614374 25429.084863312688 27460.116843171447 27190.267348809255 24618.929144278867 1.261096492641582 1.2137324389973418 1.1804913936520842 1.057201500865805 1.2029931565384 1.227864740804096 1.0329078374727803 1.115406632117987 1.1044455747632684 1.0 14.587480389469393 -1.522878745436693 0.07855556861314841 0.8726344052289837 1.8372517494425957 0.5482069072555427 0.05751567188492101 168.48874117348885 0.9705225859882065 1.8381813508249754 17.68133792951126 0.02999999998919935 1.522878745436693 0.964617344213612 EREQQIEEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EREQQIEEHR 10 1 Q16643-3;Q16643;Q16643-2;D6R9W4 Q16643-3 DBN1 Drebrin 0 ; 77.288 0.0098999 8555300.0 30682.0 27680.0 33762.0 32742.0 34055.0 37710.0 35120.0 32417.0 30843.0 25753.0 False True 35875.85660287714 30427.887469252924 34567.014123098 30907.571890996245 27382.16721586299 35732.421215339 31793.17935321883 31566.088098650634 31294.02052577668 30421.81503936417 1.1792806101955369 1.0001996077446693 1.1362574546709383 1.0159673856081082 0.9000832849858551 1.1745657242706655 1.0450783200174016 1.0376135696639348 1.0286703960721582 1.0 14.892818609869376 -4.750700844822228 24.932052942198005 1.0414022812816883 1.1792809120600452 0.2603643467610063 0.07137911719523828 652.1517051450248 1514022.3427494413 0.01753799484391589 0.24915657250317796 1.775412017290543e-05 4.750700844822228 0.13787863077835683 EREQQIEEHR ddPTM_PC-9_Lapatinib_30min_R1 1 EREQQIEEHR 10 1 Q16643-3;Q16643;Q16643-2;D6R9W4 Q16643-3 DBN1 Drebrin 0 95.48299999999999 0.0026579999999999998 3731400.0 10994.0 8983.0 13006.0 8530.7 11076.0 11462.0 8429.9 9991.1 13134.0 8738.9 False True 10837.223543947322 8962.20041541388 11936.696884611856 9158.076135580977 10424.531456253831 10971.796979227018 8866.358974182516 10455.322980303765 11654.71061284857 10249.407221147692 1.057351250673969 0.8744115851814427 1.1646231462033008 0.8935225167641928 1.0170862793649962 1.0704811256390332 0.8650606598875766 1.0200905042324013 1.137110699319401 1.0 13.323252852807927 -8.009776904130979 24.824518469000797 1.0719037854746025 0.9904602013480547 0.09322233994589602 0.0948318391572422 891.381457125231 2263293.3937251186 0.053141451359475116 0.023099813722499765 9.777393539628842e-09 8.009776904130979 -0.08144358412654784 ERES(ph)SNPSDR ddPTM_PC-9_AZD4547_30min_R2 2 ERESSNPSDR 10 1 Q9Y388 Q9Y388 RBMX2 RNA-binding motif protein, X-linked 2 1 ERES(0.5)S(0.5)NPS(0.001)DR;ERES(0.497)S(0.497)NPS(0.005)DR 142.12 0.00060938 3848600.0 12501.9 10842.5 9389.2 10413.5 8940.1 10078.900000000001 10230.8 11351.0 17383.9 15086.599999999999 True False 16477.244144325727 14347.126088356292 9264.693073205699 8012.828461971192 7698.921432358963 9448.664789697485 11141.321380314226 9596.963770031072 18302.777464064762 14558.422726003651 1.1318014632790374 0.9854862960346693 0.6363802760485507 0.5503912486109508 0.5288293640908962 0.6490170650712506 0.7652835468511338 0.6592035380927203 1.2571950827731564 1.0 13.829566440536983 -8.256198015980727 24.989585383668892 1.1285975552128935 0.7278188661678405 0.40659779755007763 0.1882628293557559 415.0991656602149 1979118.922750148 0.1486177249520563 0.05245463336025578 5.5437288975696295e-09 8.256198015980727 -0.400778689045053 ERES(ph)SNPSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ERESSNPSDR 10 1 Q9Y388 Q9Y388 RBMX2 RNA-binding motif protein, X-linked 2 1 ERES(0.496)S(0.496)NPS(0.007)DR;ERES(0.386)S(0.386)NPS(0.228)DR 112.44 0.007004600000000001 3510700.0 2077.04 6370.0 5381.200000000001 4840.5 11633.6 14043.9 4753.0 6677.2 14810.7 13151.2 True False 2428.6418485900517 7002.371502136605 5509.508216314646 4569.302478112738 9354.079592496371 13307.413161127015 4302.761431259943 6501.930575078201 15027.27846840842 15535.408455158087 0.15632944930930934 0.4507362340905603 0.35464199298122556 0.2941218115572386 0.6021135279124649 0.8565859854626912 0.276964808725794 0.4185233104005979 0.967292138586742 1.0 13.923272552678617 -8.287336624584414 0.14597653016770096 1.3380067096795647 2.1802667766995093e-17 0.5305568784817565 0.1976468438364382 5.153128520238474 0.6677530008004746 2.897176277645914 2.362839856635386 5.1601624654737865e-09 8.287336624584414 -1.3380067096795647 ERES(ph)SNPSDR ddPTM_PC-9_Lapatinib_30min_R1 1 ERESSNPSDR 10 1 Q9Y388 Q9Y388 RBMX2 RNA-binding motif protein, X-linked 2 1 ERES(0.5)S(0.5)NPSDR 163.71 0.0034567 2617900.0 3536.3 8327.6 5957.9 5420.4 11127.0 3680.0 17691.0 14678.0 8908.9 7543.8 True False 3485.871713522002 8308.317953846221 5468.06446015908 5819.034297924333 10472.531736523695 3522.6149784989902 18606.95341727219 15359.993464673431 7905.4858671240045 8847.735778518352 0.3939846081282672 0.9390332353751117 0.6180185074508143 0.6576862650049426 1.1836397467869946 0.398137451962754 2.1030186573211753 1.7360366368496625 0.8935038370288971 1.0 13.111092587423563 -7.248088555384896 24.918286481315928 1.4944762045905693 0.7259035088431418 0.45584240349326755 0.39028074273100555 646.7833979627541 1207173.2121637615 0.146676461958152 0.11293559979721268 5.6482179234247196e-08 7.248088555384896 -0.7685726957474275 ERESS(ph)NPSDR ddPTM_PC-9_Lapatinib_30min_R1 1 ERESSNPSDR 10 1 Q9Y388 Q9Y388 RBMX2 RNA-binding motif protein, X-linked 2 1 ERES(0.321)S(0.679)NPSDR 77.64399999999999 0.010137 2817600.0 3570.2 8706.7 4661.5 5809.1 7521.5 4007.7 11514.0 12328.0 6728.7 7570.2 True False 3519.288293305504 8686.540171088052 4278.249463910364 6236.320592589517 7079.100157837957 3836.300013404998 12110.138581565323 12900.803885576654 5970.842949647795 8878.698983342561 0.3963743223988205 0.9783573232277588 0.48185544660730606 0.7023912629867908 0.7973127787212007 0.43207907156243597 1.3639541789045113 1.4530061115688249 0.6724907512744568 1.0 13.11613257522491 -7.262478467800154 24.99987342314074 1.1601132744416156 0.6511376086921145 0.46235966153949926 0.2575584833629139 82.05981915817462 1974274.4431489056 0.09987742132170116 0.07169754246187134 5.464136402468731e-08 7.262478467800154 -0.5089756657495011 ERESSANNSVS(ph)PSESLR ddPTM_PC-9_AZD4547_30min_R2 2 ERESSANNSVSPSESLR 17 1 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 ERESSANNSVS(0.947)PS(0.05)ES(0.002)LR;ERESS(0.001)ANNS(0.005)VS(0.798)PS(0.171)ES(0.025)LR 87.49600000000001 0.0013615 16132400.0 36913.0 25321.6 44015.0 53370.0 32161.0 35775.0 32001.0 36932.0 34941.0 32580.0 True False 48650.56616190299 33506.31200912358 43431.332341109926 41066.37105828035 27696.000289269312 33537.98359458148 34849.027005848584 31225.008012931685 36787.90992653471 31439.3841165802 1.54744017826501 1.0657432691708915 1.3814307614952777 1.3062078730932634 0.8809332964847508 1.0667506548544168 1.1084513257837718 0.9931812880667894 1.1701218379508223 1.0 14.940285335674645 -6.23411095178264 22.639620828506946 1.0413349577512816 1.3106887927292812 0.5355223510042223 0.1313646521786671 186.52376152915065 154520.57922624997 0.03681549024024109 0.04750736209005328 5.832960671370354e-07 6.23411095178264 0.2693538349779996 ERESSANNSVS(ph)PSESLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ERESSANNSVSPSESLR 17 1 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 ERESSANNS(0.264)VS(0.7)PS(0.027)ES(0.009)LR;ERESSANNS(0.12)VS(0.855)PS(0.022)ES(0.003)LR;ERESSANNS(0.005)VS(0.577)PS(0.374)ES(0.044)LR 74.742 0.004443600000000001 20062100.0 33741.9 40541.0 59240.0 46469.0 50660.0 46192.0 44572.0 41039.0 45982.0 34563.0 True False 39453.73723709737 44565.642553864986 60652.50626895111 43865.49258453068 40733.53666585286 43769.61020363141 40349.81748666488 39961.76973441476 46654.39976060251 40828.99829944256 0.9663165612768911 1.0915193712815983 1.4855252099040404 1.074371020881244 0.9976619158547663 1.0720226316262331 0.9882637137148617 0.9787594944488354 1.142678040211422 1.0 15.317306552398964 -5.983533651589283 24.99982981597893 1.0295106734559432 1.1901248934158042 0.21335287856839724 0.12955728542474854 361.2135805189967 548403.9230356311 0.03734650599187755 0.055378920239659075 1.0386431193695428e-06 5.983533651589283 0.16061421995986103 ERESSANNSVS(ph)PSESLR ddPTM_PC-9_Lapatinib_30min_R1 2 ERESSANNSVSPSESLR 17 1 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 ERESSANNS(0.015)VS(0.97)PS(0.011)ES(0.004)LR;ERES(0.006)S(0.002)ANNS(0.018)VS(0.973)PSESLR 102.72 0.00044375 9969500.0 27435.0 25075.0 28564.0 22938.0 23678.0 25405.0 22346.9 20392.9 29909.0 20634.6 True False 27043.771869037184 25016.9403781034 26215.5781802286 24624.937038924872 22285.306592739107 24318.487371947504 23503.91313777853 21340.428581941607 26540.333464267376 24201.26311612378 1.1174529089359646 1.0337039128109056 1.0832318153990403 1.0175062731547604 0.9208323749801227 1.0048437246957422 0.9711853891675327 0.8817898668984686 1.0966507548354045 1.0 14.562794726380409 -5.951043740264239 4.325657185692869 0.9736077773577263 1.0726974487344714 0.3768257759486149 0.05636630263726035 0.20934418276400402 8.396033891670553 0.015526983140097633 0.023204310761168526 1.1193251441964546e-06 5.951043740264239 0.09908967137674507 ERESSANNSVSPS(ph)ESLR ddPTM_PC-9_AZD4547_30min_R2 1 ERESSANNSVSPSESLR 17 1 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 ERESSANNS(0.001)VS(0.247)PS(0.66)ES(0.093)LR 83.727 0.0017094999999999999 6939000.0 10352.0 11674.0 19340.0 29018.0 21372.0 14951.0 14070.0 18467.0 15150.0 16772.0 True False 13643.720665023706 15447.392202487546 19083.53896346848 22328.348423630876 18404.866707573252 14016.111606501401 15322.20274279834 15613.349479443541 15950.798070661995 16184.817384999482 0.8429950329664558 0.9544372256436208 1.1791012842168742 1.3795860584948818 1.137168635874222 0.8660036917989513 0.9467022319942493 0.9646911119253287 0.9855408121839927 1.0 13.982353467108155 -6.748377252921766 24.922467702033714 0.9500129262169259 1.110721654180888 0.22149246116083332 0.13594505700682782 365.1251168142258 696655.5420069387 0.05056786803134668 0.05026828730889585 1.78493640381231e-07 6.748377252921766 0.16070872796396207 ERESSANNSVSPS(ph)ESLR ddPTM_PC-9_Lapatinib_30min_R1 1 ERESSANNSVSPSESLR 17 1 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 ERESSANNSVS(0.173)PS(0.793)ES(0.035)LR 87.35600000000001 0.0013727000000000001 7504900.0 7572.4 8145.5 9120.3 7625.9 4565.2 5435.8 7323.2 7411.0 10365.0 7894.3 True False 7464.4161873919165 8126.639595208031 8370.46413937609 8186.734125256651 4296.683911528529 5203.323505468699 7702.359463307207 7755.342115185642 9197.584551711238 9258.81923650645 0.8061952606181779 0.8777187876360772 0.9040530898769815 0.884209305326678 0.46406391590271073 0.5619856455294644 0.8318943557011781 0.8376167540464802 0.99338633974473 1.0 13.176612505118092 -8.085475908186883 2.0642069846421376 1.0045603163079875 0.7563606329152136 0.32265719231279844 0.13541807112522974 0.46701292402857053 3.5609654827720782 0.13558385090256891 0.04296478736937669 8.213421142513182e-09 8.085475908186883 -0.24819968339277387 EREVDEDS(ph)EPER ddPTM_PC-9_AZD4547_30min_R2 1 EREVDEDSEPER 12 1 F8WC91;B9A018;Q53GS9-3;Q53GS9 F8WC91 USP39 U4/U6.U5 tri-snRNP-associated protein 2 1 EREVDEDS(1)EPER 53.861000000000004 0.041395 1405600.0 1344.7 1161.6 3905.5 4442.4 3594.4 2924.2 3826.6 3876.8 3344.7 1437.5 True False 1772.286628502451 1537.0644836739373 3853.710518191632 3418.273314395816 3095.379603860255 2741.3493117337584 4167.159986893539 3277.729640001449 3521.4940136596165 1387.1735625409463 1.2776242831906892 1.1080549148142855 2.7781026269940026 2.4642001597366203 2.231429207885359 1.9762121956190613 3.0040653162826794 2.362883584659362 2.5386109631509575 1.0 10.437932592980864 -5.251099285427852 24.584094443217296 2.360903665099147 1.192839373237301 0.41736464370389614 0.5158636468813351 468.57311861014267 1114049.0649000437 0.1226895154995717 0.31677709002720106 5.609197277497238e-06 5.251099285427852 -1.1680642918618458 EREVDEDS(ph)EPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EREVDEDSEPER 12 1 F8WC91;B9A018;Q53GS9-3;Q53GS9 F8WC91 USP39 U4/U6.U5 tri-snRNP-associated protein 2 1 EREVDEDS(1)EPER;EREVDEDS(1)EPER 136.6 0.00030155 2588000.0 4412.9 7579.7 4960.4 6059.2 5917.8 5634.0 6254.6 6456.6 6749.1 2166.5 True False 5159.916811252091 8332.162523507815 5078.674748421757 5719.72266819145 4758.249571282749 5338.543121909838 5662.119008617384 6287.121091333183 6847.792819457235 2559.2692999954374 2.016167978595019 3.2556802535484133 1.98442373705292 2.2349045753808117 1.8592219159160903 2.0859638029961736 2.212396721449938 2.4566078651216547 2.675682789407681 1.0 11.321516248110667 -5.32129423437657 24.999199573437398 2.120596242797882 2.6359372147493327 0.1631586301811785 0.5054216131579458 394.176027838841 164632.164654765 0.12463194965757175 0.259442200964103 4.772058572927533e-06 5.32129423437657 0.5153409719514506 EREVDEDS(ph)EPER ddPTM_PC-9_Lapatinib_30min_R1 1 EREVDEDSEPER 12 1 F8WC91;B9A018;Q53GS9-3;Q53GS9 F8WC91 USP39 U4/U6.U5 tri-snRNP-associated protein 2 1 EREVDEDS(1)EPER 98.943 0.017098 0.0 1141.9 2093.3 2051.1 1008.6 1067.4 2406.7 2094.1 4400.1 2315.1 991.26 True False 1125.6162966011861 2088.4530924619685 1882.4664754749635 1082.7758085909684 1004.6176305891428 2303.771051291718 2202.5222514900065 4604.5447093547855 2054.349058916226 1162.597970229075 0.9681904883933334 1.796367399515127 1.6191895424555471 0.9313415611568816 0.8641143854665391 1.9815715408807995 1.8944831385315664 3.9605648962620497 1.7670330686294276 1.0 10.183136579556459 -7.087741374362733 2.5770650916580338 2.414581396428495 1.2805487067550438 0.21864817780463963 0.7684667122033219 0.357795265415819 4.656793125421501 0.32036455249564916 0.2416503462739632 8.170687971360811e-08 7.087741374362733 -1.1340326896734512 EREVEER ddPTM_PC-9_AZD4547_30min_R2 1 EREVEER 7 1 E7EX17;P23588-2;P23588;F8VX11 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 96.19 0.016702 3372500.0 12099.0 6741.2 6897.3 6033.3 5552.8 5531.7 5642.9 6420.4 9590.0 13419.0 False True 15946.230325166322 8920.161068649055 6805.837295384239 4642.415898555801 4781.889568304924 5185.801924532391 6145.10716825421 5428.2747061146565 10096.907821626966 12949.20489442572 1.231444745463155 0.6888578211075292 0.5255795510899643 0.3585097259951639 0.3692805548519351 0.4004726133235206 0.4745547868270669 0.41919752991563064 0.7797318757365103 1.0 13.66057589598752 -10.567460781271771 21.270247829069554 0.9999999999999651 0.5582158881188897 0.1890557779254327 0.2544064087553396 0.0 0.0 0.2565080601802211 0.062212342702667255 2.707317675740753e-11 10.567460781271771 -0.44178411188107547 EREVEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EREVEER 7 1 E7EX17;P23588-2;P23588;F8VX11 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 ; 90.37 0.020706 6770200.0 8341.4 16864.7 10757.6 9632.5 24311.1 17422.1 9530.6 20702.1 24135.0 24409.8 False True 9753.434269840283 18538.915961080547 11014.101982425189 9092.822253986353 19547.51447369159 16508.454406145804 8627.792572431308 20158.691810688088 24487.928716065908 28835.10351212953 0.33824863037989394 0.6429287119875302 0.38196852589039915 0.31533863751040264 0.6779068597922285 0.5725124031270252 0.2992114305676764 0.6991024603816075 0.8492401875985991 1.0 14.815538580934179 -8.16171755739497 2.2705939657567886 0.9650834156939143 0.4724848676055863 0.6596388371417615 0.13344167138914986 0.19035065229502385 1.7488417432625678 0.1187366753990587 0.03606694406417368 6.891003057440261e-09 8.16171755739497 -0.49259854808832804 EREVEER ddPTM_PC-9_Lapatinib_30min_R1 2 EREVEER 7 1 E7EX17;P23588-2;P23588;F8VX11 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 ; 96.19 0.016702 9997600.0 12721.6 16666.0 9647.599999999999 12633.599999999999 18117.4 7686.700000000001 23039.3 26508.8 18013.3 18225.5 False True 12540.187651144288 16627.41090095598 8854.411568812962 13562.717088454148 17051.770152178884 7357.957759572879 24232.162221839313 27740.49562313222 15984.452465541734 21375.75339104777 0.5866547682195921 0.7778631516173643 0.4142268769119135 0.6344907166703306 0.7977155162783744 0.34421980947134306 1.1336284517572988 1.2977552236708545 0.747784284985065 1.0 14.383687648407589 -7.277054066721952 24.949816731212994 1.0696049655735247 0.6040822142891349 0.5912922564321778 0.1835921031728007 543.8756590337632 869024.3831989135 0.07415031800632339 0.050188553982431314 5.2837946801487015e-08 7.277054066721952 -0.4655227512843898 ERGDES(ph)PLGAEGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ERGDESPLGAEGAK 14 1 A0A590UJ23;K7EKN5;A0A590UJ36;A6NDB9 A0A590UJ23 PALM3 Paralemmin-3 1 ERGDES(1)PLGAEGAK 87.824 0.042296 0.0 12336.0 10648.0 13804.0 11854.0 25087.0 15096.0 12101.0 13096.0 12310.0 10883.0 True False 14424.241152893972 11705.063069819542 14133.139711961525 11189.858811186532 20171.382438536333 14304.339185010824 10954.705676346843 12752.243876358965 12490.010461768017 12856.001750219404 1.1219850022692945 0.9104746014537358 1.0993417694362344 0.8703996023488066 1.5690245560360228 1.11265846590031 0.8521082906790898 0.9919292268407891 0.9715314842388583 1.0 13.650154410083983 -7.231563433086494 21.86499985296635 0.9532197407149587 1.113677059002783 0.16023609459146637 0.17953766623980055 298.454438743426 218426.07144299863 0.0711369721088855 0.05508452331237285 5.8672766587053486e-08 7.231563433086494 0.16045731828782417 ERGDES(ph)PLGAEGAK ddPTM_PC-9_Lapatinib_30min_R1 2 ERGDESPLGAEGAK 14 1 A0A590UJ23;K7EKN5;A0A590UJ36;A6NDB9 A0A590UJ23 PALM3 Paralemmin-3 1 ERGDES(1)PLGAEGAK;ERGDES(1)PLGAEGAK 155.63 6.0886000000000006e-05 10875000.0 105711.0 111920.0 38588.0 26354.0 43873.0 23431.0 23121.0 21455.7 57064.0 16142.1 True False 104203.54175497696 111660.85611634403 35415.44359398757 28292.161074366795 41292.47639763671 22428.910750328763 24318.09224807814 22452.61014988376 50636.85140944044 18932.24047700376 5.504025890731151 5.89792086425133 1.8706419684984088 1.494390540239131 2.1810665487686487 1.1846939498561868 1.2844804225689168 1.1859457509614908 2.674635971952026 1.0 14.20855753194317 -5.279539219072258 6.166742797985603 1.5951504509756476 5.720384004925114 0.9165928426595238 0.4938589560487564 0.03559940389518415 5.7314793981103715 0.12571490674719188 0.28464078817111266 5.253645697884152e-06 5.279539219072258 4.1252335539494664 ERGDYVLAVK ddPTM_PC-9_Lapatinib_30min_R1 1 ERGDYVLAVK 10 1 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;A0A0A0MT44 O75369-2 FLNB Filamin-B 0 141.1 0.00016112 4234100.0 36184.0 34357.0 36603.0 31179.0 34173.0 30543.0 34247.0 31340.0 36113.0 31189.0 False True 35668.00952466706 34277.448477387785 33593.64263166597 33472.00767009498 32163.011326702977 29236.74708921048 36020.142088142034 32796.170812294935 32045.573653251133 36579.977093269794 0.9750692143333648 0.9370549464803891 0.9183614999542122 0.9150363212297736 0.8792518170444815 0.7992554783362517 0.9846955889638662 0.8965607257946855 0.8760413810960825 1.0 15.15876655120698 -4.912504099307927 1.294597501516159 0.9008682340681812 0.9949934541104426 0.12613916844625217 0.05339274714136422 2.1068392780471727 3.681123660146084 0.015895759395790226 0.24821540504642572 1.2231955732459115e-05 4.912504099307927 0.09412522004226143 ERGS(ph)PLLGDHAVR ddPTM_PC-9_Lapatinib_30min_R1 1 ERGSPLLGDHAVR 13 1 Q9C073;D6RFX7;D6RJ87 Q9C073 FAM117A Protein FAM117A 1 ERGS(1)PLLGDHAVR 67.415 0.016600999999999998 2997200.0 7774.1 8370.8 6442.6 6215.1 7955.1 10536.0 6105.6 7327.3 7447.1 4457.6 True False 7663.239908404668 8351.417926900422 5912.914297155186 6672.179186965817 7487.19665832836 10085.399840615584 6421.71809306976 7667.753107623763 6608.329176560424 5228.090220621353 1.465781879237329 1.5974127404993146 1.1309893379101714 1.276217300276971 1.4321093061470762 1.9290791503244076 1.2283104961999958 1.466645138865346 1.264004425649531 1.0 12.352068322451883 -8.633408605523183 1.7269467834171828 0.9995915643026072 1.4427779965113352 0.30051284658126387 0.2082453691214909 0.6819413387140212 4.307195329284425 0.2061639174331001 0.05871721630273567 2.3259019054509376e-09 8.633408605523183 0.443186432208728 ERGT(ph)PPVDPK ddPTM_PC-9_Lapatinib_30min_R1 1 ERGTPPVDPK 10 1 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 ERGT(1)PPVDPK 92.039 0.005541300000000001 47338000.0 589590.0 483810.0 464870.0 481180.0 510940.0 420110.0 404450.0 403850.0 428540.0 401650.0 True False 581182.3384824361 482689.7676701976 426650.1830500936 516567.58236942533 480887.513746689 402142.8746242421 425390.442010951 422614.3453269086 380273.31247374177 471074.6673350155 1.233737194509581 1.0246566014701906 0.9056954504978116 1.0965726204123316 1.0208307665262222 0.8536711959045953 0.903021265009831 0.8971281510800426 0.8072463642017534 1.0 18.845596225689476 -6.6735012530491025 5.199860630248111 0.8867406221460234 1.0513892272162542 0.46421079628430595 0.08839066380915725 0.20060189774108317 9.009526612920212 0.0298862530884185 0.029623998556427607 2.120795274052069e-07 6.6735012530491025 0.1646486050702307 ERHPS(ph)WR ddPTM_PC-9_AZD4547_30min_R2 2 ERHPSWR 7 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 ERHPS(1)WR;ERHPS(1)WR 72.243 0.018565 827620000.0 236133.0 249140.0 309300.0 435760.0 311401.0 265205.0 269674.0 362326.0 275916.0 323523.0 True False 311218.3821284812 329669.6328017604 305198.47990697005 335302.26442488766 268168.3463225264 248621.68942560352 293674.4635722393 306336.842123186 290500.35646632157 312196.5582427374 0.996866794048717 1.0559681844584508 0.9775843834565076 1.0740101246221467 0.8589727825058904 0.7963626851782797 0.9406716884556529 0.9812306831550802 0.9305046734065957 1.0 18.25209510709695 -6.260246860180706 24.99593497187591 0.9120746295561407 1.0247743595412941 0.4343147426387972 0.0602352862554929 106.44157473644485 2231081.95814769 0.019293699331579338 0.023540212688958152 5.492285944786469e-07 6.260246860180706 0.11269972998515343 ERHPS(ph)WR ddPTM_PC-9_Lapatinib_30min_R1 1 ERHPSWR 7 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 ERHPS(1)WR 58.246 0.039589 5938400.0 22594.0 16641.0 17727.0 19153.0 28283.0 24491.0 20624.0 20247.0 30455.0 30623.0 True False 22271.805416767864 16602.468786919988 16269.554488198863 20561.575512534997 26619.44954651744 23443.577021309447 21691.809805992987 21187.749535307474 27024.837194632495 35916.14474741738 0.6201056815366957 0.4622564282352109 0.4529872179382159 0.5724883797282703 0.7411555369798304 0.6527308870753787 0.6039570772014105 0.5899227125937848 0.752442596071667 1.0 15.132344878507052 -14.522878744764986 0.12939634212694376 2.3801982977760514 0.42819960943589397 0.741813596405122 0.07667973751987282 79.09852194233879 0.6444142050177687 28.084486689734913 0.646470220039885 3.000000003559922e-15 14.522878744764986 -1.9519986883401574 ERHPSWR ddPTM_PC-9_Lapatinib_30min_R1 1 ERHPSWR 7 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 80.219 0.039819 0.0 7942.5 6728.5 8469.8 6841.3 9004.3 9712.5 9385.0 10157.0 11598.0 9863.9 False True 7829.238493523883 6712.9205716478045 7773.445738373479 7344.432023907781 8474.684777134924 9297.11901594332 9870.90937884233 10628.93129995149 10291.711107645626 11568.861972179426 0.6767509641269369 0.5802576422634227 0.6719282983120475 0.6348448137396339 0.7325426474544066 0.8036329794841405 0.8532308020079851 0.9187534024964371 0.8896044513621938 1.0 13.49795933320456 -7.032415819643624 0.6726670510785259 0.9677703765749455 0.6146362378485098 0.9331915731785001 0.033799580171832114 0.16231436822102654 0.15351392692475638 0.026350162306814855 0.021328065011047233 9.280773641882295e-08 7.032415819643624 -0.3531341387264356 ERKECS(ph)ESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ERKECSESR 9 2 A0A1W2PQ30 A0A1W2PQ30 1 ERKECS(0.5)ES(0.5)R 56.258 0.02797 1407600.0 3505.6 1220.9 4123.9 6344.0 4639.8 7502.5 3180.6 6905.2 4689.4 5364.5 True False 4099.028841243928 1342.102883352995 4222.229415977844 5988.5662475255085 3730.664497082989 7109.055692603579 2879.310542450109 6723.945816664167 4757.973603526804 6337.041384641364 0.6468363692840088 0.21178698416042446 0.6662777090600924 0.9450098056862261 0.5887076114296389 1.1218256692836646 0.45436195973541993 1.0610544272222233 0.7508193989482799 1.0 12.629593721879491 -5.500476382170812 6.6773711068741815 0.8315163420299758 0.42932760383422475 0.3641423299216978 0.2192501786929803 0.16849657427421622 30.10829836321442 0.05340971964347635 0.10577541320542085 3.1588108263969737e-06 5.500476382170812 -0.40218873819575107 ERLDDWDR ddPTM_PC-9_AZD4547_30min_R2 1 ERLDDWDR 8 1 H0YIQ2;P49750-3;P49750-1;P49750 H0YIQ2 YLPM1 YLP motif-containing protein 1 0 94.309 0.008779299999999999 3317100.0 7135.6 7846.5 11968.0 10970.0 10744.0 10454.0 8736.1 12119.0 10201.0 10609.0 False True 9404.572370299762 10382.727678329495 11809.296500247721 8441.035984810484 9252.381054939511 9800.30972740056 9513.595975931807 10246.287016915387 10740.204034245746 10237.582139128284 0.9186321772555319 1.014177716694107 1.15352398054149 0.8245146041416012 0.9037662339798661 0.9572875308070585 0.9292815282595501 1.0008502864903845 1.0490957618983519 1.0 13.321587406628202 -10.08332819035338 7.991120559464883 0.9999999983879675 0.9716703521423659 0.009308052226625785 0.08532660207440955 0.0 0.0 0.08563439074594775 0.020769390484174012 8.25413959885222e-11 10.08332819035338 -0.028329646245601636 ERLELCDER ddPTM_PC-9_AZD4547_30min_R2 2 ERLELCDER 9 1 P07919 P07919 UQCRH Cytochrome b-c1 complex subunit 6, mitochondrial 0 ; 106.88 0.0026642 5711400.0 57868.0 44878.0 69428.0 85161.0 84068.0 63738.0 58311.0 80740.0 59526.0 63500.0 False True 76268.8202708261 59383.93586287785 68507.33935655074 65528.44717433412 72396.60931930883 59752.452784107176 63500.56603662501 68263.48822062451 62672.42283526248 61276.88432789573 1.2446589135098278 0.9691082781740564 1.1179964534417983 1.0693828169149082 1.1814668796133774 0.9751222412740301 1.0362890792036723 1.1140169571178442 1.022774305885057 1.0 15.903055323696018 -6.768424082379316 24.999321142744957 1.0371821271407164 1.105795977188315 0.24168547878031943 0.07517528372059863 299.97505427374796 1073649.1457244146 0.025342693188154245 0.022837261968526267 1.7044172369676034e-07 6.768424082379316 0.06861385004759857 ERLELCDER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ERLELCDER 9 1 P07919 P07919 UQCRH Cytochrome b-c1 complex subunit 6, mitochondrial 0 ;;; 96.665 0.0065225 14096800.0 117202.0 110981.0 129325.0 138334.0 151708.0 125949.0 146729.0 122218.0 120148.0 118852.0 False True 137041.98375498372 121998.46023212261 132408.5984677937 130583.59446487905 121981.90644499027 119344.01271945717 132829.76689403297 119009.907000675 121904.93720231575 140398.92676808534 0.976089966708601 0.8689415442159533 0.9430883947318893 0.9300896913591119 0.868823638847918 0.8500350783777199 0.9460881927783159 0.8476553898254415 0.8682754206781192 1.0 17.09917238192915 -4.747300425806202 24.756189135318937 0.8985866406491219 0.9760901894464367 0.1695112187794462 0.04811299446476143 1115.5192217519843 1953058.85150783 0.01151299804304022 0.23544829438063591 1.7893676200499904e-05 4.747300425806202 0.0775035487973148 ERLGS(ph)FGSITR ddPTM_PC-9_AZD4547_30min_R2 3 ERLGSFGSITR 11 1 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 1 ERLGS(0.959)FGS(0.041)ITR;ERLGS(0.995)FGS(0.005)ITR;ERLGS(1)FGSITR 120.84 0.0028281 50102000.0 87735.0 70408.9 108382.0 219213.0 188270.0 123329.0 93348.0 118766.0 70186.7 131402.0 True False 115632.90499863384 93167.20000391679 106944.78386445933 168676.82965708865 162131.96027675565 115617.21813378444 101655.79116096231 100413.44367117503 73896.62567301202 126801.65597565599 0.9119195179977272 0.7347475022077274 0.8434021073430706 1.330241536352428 1.2786265213120132 0.9117958061681877 0.8016913531514028 0.7918937879679813 0.5827733486950601 1.0 16.952214061020335 -7.1337246601486575 3.8531858589513552 0.7767584763869655 1.0171352227111325 0.22421135913949886 0.19452127374258701 0.39715117258953675 10.317348313353737 0.08694036201753678 0.06620972443987683 7.349796927783384e-08 7.1337246601486575 0.24037674632416706 ERLGS(ph)FGSITR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ERLGSFGSITR 11 1 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 1 ERLGS(0.994)FGS(0.006)ITR;ERLGS(0.992)FGS(0.004)IT(0.004)R;ERLGS(0.993)FGS(0.007)ITR;ERLGS(0.99)FGS(0.009)ITR 74.475 0.010754999999999999 20743800.0 17440.1 9897.5 14896.900000000001 33263.2 39002.9 52479.3 43388.9 42173.9 45019.7 35945.3 True False 20392.364472323778 10880.058389701258 15252.098592807866 31399.57074474943 31360.56172966035 49727.193123472316 39278.78928356711 41066.87981194071 45678.02794359528 42461.89834716174 0.48025089000023136 0.2562310874739426 0.3591949297252122 0.739476376869247 0.7385576940828545 1.1711015065061547 0.9250361103130614 0.9671465810639086 1.0757415405721849 1.0 15.373881250906136 -6.085666394877559 1.457608202391551 1.0130908485087315 0.3385455559282802 0.8690656720487698 0.1078734135318082 0.12962982884628232 0.5545884724871398 0.03761031680619477 0.06103780949412743 8.209819428898536e-07 6.085666394877559 -0.6745452925804514 down ERLGS(ph)FGSITR ddPTM_PC-9_Lapatinib_30min_R1 4 ERLGSFGSITR 11 1 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 1 ERLGS(0.996)FGS(0.004)ITR;ERLGS(1)FGSITR;ERLGS(0.847)FGS(0.151)IT(0.002)R;ERLGS(0.991)FGS(0.009)ITR 122.52 0.0023511 59800000.0 178515.0 76259.3 117217.0 105767.0 151095.0 173357.0 120058.0 122451.0 179203.0 143380.0 True False 175969.34336435876 76082.72627620741 107579.87073070511 113545.45800836905 142207.88916419953 165942.9252249047 126274.01579169433 128140.52048935334 159019.2710487516 168163.04195815936 1.046421028754592 0.45243428871331637 0.6397355178522047 0.6752105378577791 0.8456548330017857 0.9867978319885112 0.7509023048186328 0.762001680019775 0.9456255619371894 1.0 17.359501146484277 -6.293824436481564 5.267230161266275 0.8699815361311454 0.680447496507612 0.2277642010547899 0.15811098668966442 0.28154796292500006 21.97030984916431 0.04812696190008212 0.0562974824151636 5.083649075117411e-07 6.293824436481564 -0.18953403962353332 ERLNS(ph)SENGEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ERLNSSENGEDR 12 1 Q7L4I2;H0YGP9;E1B6W4;Q7L4I2-2 Q7L4I2 RSRC2 Arginine/serine-rich coiled-coil protein 2 1 ERLNS(0.5)S(0.5)ENGEDR 120.21 0.0024300999999999997 12365000.0 24638.0 27701.0 36628.0 28977.0 35607.0 37537.0 37739.0 35933.0 33205.0 38582.0 True False 28808.726777318552 30450.97221046876 37501.35043246354 27353.51263470153 28630.063956988222 35568.493639888104 34164.088713300844 34989.79682416056 33690.5603073117 45576.61118505604 0.6320945333198565 0.6681271691488381 0.822820070588305 0.6001655657029275 0.6281744783687567 0.7804111081332553 0.74959694950955 0.767713875919613 0.7392072256209866 1.0 15.476006037626341 -14.522878744218723 0.1679324626295282 2.142302129914841 0.6399393846067739 0.6745580690322013 0.06398668347665636 81.81424503468955 0.765416399844922 30.953341483652224 0.24797352265846784 3.0000000073333762e-15 14.522878744218723 -1.502362745308067 ERLNSS(ph)ENGEDR ddPTM_PC-9_AZD4547_30min_R2 2 ERLNSSENGEDR 12 1 Q7L4I2;H0YGP9;E1B6W4;Q7L4I2-2 Q7L4I2 RSRC2 Arginine/serine-rich coiled-coil protein 2 1 ERLNS(0.18)S(0.82)ENGEDR;ERLNS(0.209)S(0.791)ENGEDR 114.31 0.0037387 25425000.0 45888.0 46547.0 62360.0 76600.0 73885.0 60267.0 70828.0 82821.0 61567.0 66374.0 True False 60479.429470305964 61592.407473803985 61533.06565469983 58941.05345820261 63627.343097934216 56498.49496281322 77131.55478798297 70022.91748724738 64821.30592847834 64050.266462673324 0.9442494592204649 0.9616260926829756 0.9606996044358309 0.9202311982972277 0.9933970085044755 0.8820961735692222 1.2042347213798563 1.0932494328974376 1.0120380368168234 1.0 15.966916952045766 -7.246950785545222 24.998689751619736 1.085151342710604 0.9464932968203102 0.5538024401815282 0.05857922321614052 571.3194175336589 985758.5317616325 0.0218635995965014 0.016855050233293218 5.6630345917640766e-08 7.246950785545222 -0.13865804589029385 ERLNSS(ph)ENGEDR ddPTM_PC-9_Lapatinib_30min_R1 2 ERLNSSENGEDR 12 1 Q7L4I2;H0YGP9;E1B6W4;Q7L4I2-2 Q7L4I2 RSRC2 Arginine/serine-rich coiled-coil protein 2 1 ERLNS(0.172)S(0.828)ENGEDR;ERLNS(0.232)S(0.768)ENGEDR 147.1 0.00041053 20360700.0 48921.0 42753.0 50659.0 39489.0 63389.0 70275.0 69248.0 67043.0 73897.0 57690.0 True False 48223.37756898732 42654.00805523649 46494.012569395054 42393.15279144234 59660.583647569 67269.50206902614 72833.32260693368 70158.06253250434 65573.94169009222 67661.63963290701 0.7127137005638575 0.6304016321013282 0.6871546835347875 0.6265463417889828 0.881749008319232 0.9942044330286942 1.0764344908294454 1.036895690277999 0.9691450287911816 1.0 16.04605051768641 -6.4811739645891695 2.578204003187207 1.0224075724129091 0.6622597064039856 0.950571088638443 0.0376574798738543 0.05587662713415987 0.7393486270068216 0.013139031843635997 0.014436790756803163 3.302372319825636e-07 6.4811739645891695 -0.36014786600892357 ERLS(ph)WPK ddPTM_PC-9_Lapatinib_30min_R1 1 ERLSWPK 7 1 Q8IVF2-3;Q8IVF2 Q8IVF2-3 AHNAK2 Protein AHNAK2 1 ERLS(1)WPK 61.161 0.03403 11301000.0 41230.0 29896.0 38324.0 32464.0 37635.0 32172.0 33929.0 29959.0 32977.0 29914.0 True False 40642.052639344016 29826.77764880477 35173.14865491808 34851.510856729314 35421.383293256884 30796.07855659496 35685.67760412801 31351.004510706567 29262.782996795147 35084.59504210052 1.1584016458099262 0.8501388604603669 1.002524002705783 0.9933565091718599 1.0095993198938802 0.8777663963241 1.0171323785070403 0.8935831943645424 0.8340635815143552 1.0 15.098550089997856 -6.922601605341802 0.9627144541408925 0.9130573192992514 0.9963154678730963 0.13350460786886942 0.08760829761295087 1.2070412895129525 2.352690720629554 0.054142381441442344 0.04213287223229171 1.195083897176845e-07 6.922601605341802 0.08325814857384495 ERPDLEAPAPGS(ph)PFR ddPTM_PC-9_AZD4547_30min_R2 2 ERPDLEAPAPGSPFR 15 1 Q9NQT8;H0YBA8;Q9NQT8-2 Q9NQT8 KIF13B Kinesin-like protein KIF13B 1 ERPDLEAPAPGS(1)PFR;ERPDLEAPAPGS(1)PFR 129.98 6.4258e-06 22527000.0 15076.3 15972.900000000001 30874.0 36746.0 32919.0 30094.0 32729.0 36719.0 30140.0 29126.0 True False 19870.24979347921 21135.827557916175 30464.590587286762 28274.777420040664 28348.765073301707 28212.217422650887 35641.817595525696 31044.922268678598 31733.138867970494 28106.30760526442 0.7069676341888977 0.7519958813073458 1.0839058269461417 1.0059940215962302 1.0086264432682674 1.0037681868025463 1.2681074332528064 1.10455356515289 1.1290397626626256 1.0 14.77860631532145 -4.6317551314911025 0.7283195728982059 1.107748926302927 0.3151806567436979 0.7041727426646751 0.08661625944813864 1.8890253738134783 0.6555707711289672 0.0362955836856169 1.293306358547402 2.33477410826839e-05 4.6317551314911025 -0.7925682695592291 ERPDLEAPAPGS(ph)PFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ERPDLEAPAPGSPFR 15 1 Q9NQT8;H0YBA8;Q9NQT8-2 Q9NQT8 KIF13B Kinesin-like protein KIF13B 1 ERPDLEAPAPGS(1)PFR;ERPDLEAPAPGS(1)PFR;ERPDLEAPAPGS(1)PFR;ERPDLEAPAPGS(1)PFR;ERPDLEAPAPGS(1)PFR 155.24 4.6355e-05 99541700.0 65615.8 94032.6 125047.3 133027.7 163186.0 145028.0 138035.0 116747.6 108683.8 105629.1 True False 76723.25896887651 103367.53508819603 128028.90187652611 125574.58925062265 131210.87474050245 137422.4763727972 124959.32551314225 113683.09920430738 110273.09496545087 124778.81967050479 0.6148740561216605 0.8284060977748617 1.0260467458708424 1.0063774411572348 1.0515476511717483 1.1013285486726005 1.0014466064281913 0.9110768919316824 0.8837485020025175 1.0 16.929013542053816 -4.911117802723309 2.333861704044349 1.000782242124671 0.5749092879114747 0.7982130566776743 0.06022634275955175 0.20538845448946236 1.6900913655311094 0.01817355799201498 0.1618767977066241 1.2271063324431871e-05 4.911117802723309 -0.4258729542131964 ERPDLEAPAPGS(ph)PFR ddPTM_PC-9_Lapatinib_30min_R1 4 ERPDLEAPAPGSPFR 15 1 Q9NQT8;H0YBA8;Q9NQT8-2 Q9NQT8 KIF13B Kinesin-like protein KIF13B 1 ERPDLEAPAPGS(1)PFR;ERPDLEAPAPGS(1)PFR;ERPDLEAPAPGS(1)PFR;ERPDLEAPAPGS(1)PFR 120.08 4.1125e-05 92638900.0 94413.0 79030.0 91464.0 73792.0 78864.0 67395.0 69677.7 72966.0 74571.0 59499.0 True False 93066.65330677616 78847.01089058879 83944.18298124996 79218.90984289566 74225.37457258964 64512.672955418355 73285.27037039553 76356.2667354791 66172.02871255748 69783.32287256596 1.333651787787876 1.1298832965374033 1.2029261365862973 1.135212635081313 1.063654918068827 0.9244712103094812 1.0501831577184224 1.0941907549303185 0.9482498968040945 1.0 16.090594675528788 -3.535267822583413 0.3839686111674334 0.9939296788741617 2.016494258710555 0.7211475283529245 0.0610394418004594 8.647740711059926 0.47705942165703114 0.05069027615221228 4.947301343654226 0.0002915628437233871 3.535267822583413 1.0225645798363932 ERPES(ph)PLSTGETPCESPTR ddPTM_PC-9_Lapatinib_30min_R1 2 ERPESPLSTGETPCESPTR 19 1 E7EV07 E7EV07 ARHGEF4 1 ERPES(0.907)PLS(0.073)T(0.02)GETPCESPTR;ERPES(0.993)PLS(0.006)T(0.001)GETPCESPTR 64.962 0.0051526 9852500.0 10726.6 13119.0 15606.9 14361.8 13837.4 12708.7 11169.5 12240.5 14017.3 8824.099999999999 True False 10573.636716982477 13088.623761528954 14323.760926376188 15418.014681560344 13023.51133737512 12165.178526426664 11747.802057216772 12809.238316142188 12438.524065287207 10349.333927625828 1.0216731618600023 1.2646827180434332 1.384027322583658 1.489759127435681 1.2583912576838416 1.1754552139779488 1.1351263897146042 1.237687217913614 1.2018671107021326 1.0 13.337250299908547 -6.692395717421601 4.196119316812415 1.1632429517878646 1.3029604022238657 0.2168927558097813 0.1253392490858196 0.36963191189604966 12.707304517968018 0.04538249219436138 0.044374893539472195 2.030506025440399e-07 6.692395717421601 0.13971745043600103 ERPES(ph)PMVPSEQVVEEAVPLPPQALTTSQDGHR ddPTM_PC-9_AZD4547_30min_R2 5 ERPESPMVPSEQVVEEAVPLPPQALTTSQDGHR 33 1 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 1 ERPES(0.96)PMVPS(0.04)EQVVEEAVPLPPQALTTSQDGHR;ERPES(0.952)PMVPS(0.048)EQVVEEAVPLPPQALTTSQDGHR;ERPES(0.995)PMVPS(0.005)EQVVEEAVPLPPQALTTSQDGHR;ERPES(0.957)PMVPS(0.043)EQVVEEAVPLPPQALTTSQDGHR;ERPES(0.99)PMVPS(0.01)EQVVEEAVPLPPQALTTSQDGHR 88.531 5.5912e-12 102529000.0 22792.7 15923.669999999998 92849.6 195729.0 140759.1 121393.3 63979.7 141202.0 79268.4 111308.3 True False 30040.304482388485 21070.68492316128 91618.35363714918 150606.7030329055 121217.12864392572 113802.55776078542 69673.76935489796 119382.47539916568 83458.36579435397 107411.4302966099 0.2796751183690048 0.19616799501669338 0.8529665174753829 1.4021478218567107 1.1285309981367184 1.0595013719352477 0.6486625228106379 1.1114503835345872 0.7769970622669202 1.0 16.712788001789754 -5.333667847907351 4.27803359573071 1.0198536063902004 0.23345587139456028 0.7141295081397865 0.19393387675827825 0.1106137835368212 3.8648969365802746 0.053833374482895276 0.12264392597854994 4.638015034369608e-06 5.333667847907351 -0.7863977349956401 down ERPES(ph)PMVPSEQVVEEAVPLPPQALTTSQDGHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ERPESPMVPSEQVVEEAVPLPPQALTTSQDGHR 33 1 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 1 ERPES(0.884)PMVPS(0.116)EQVVEEAVPLPPQALTTSQDGHR;ERPES(0.986)PMVPS(0.014)EQVVEEAVPLPPQALTTSQDGHR;ERPES(0.98)PMVPS(0.02)EQVVEEAVPLPPQALTTSQDGHR;ERPES(0.987)PMVPS(0.013)EQVVEEAVPLPPQALTTSQDGHR;ERPES(0.987)PMVPS(0.013)EQVVEEAVPLPPQALTTSQDGHR 84.54899999999999 1.0969e-11 76275100.0 28200.7 45526.899999999994 102266.0 114701.0 148306.0 124803.0 102265.0 90917.0 102649.0 69308.6 True False 32974.52152078607 50046.50975519981 104704.4092859645 108274.6748356595 119246.50392352902 118258.11097687506 92577.7188655163 88530.52508452439 104150.04743217096 81873.7005334244 0.4027486397457317 0.6112647825753112 1.2788527769453832 1.3224597658372248 1.456468965572741 1.4443967990502269 1.1307381767570412 1.0813060177777403 1.2720818376793948 1.0 16.321112483390877 -5.185902255683111 3.554989894896661 1.2666509972587485 0.44441810374447166 0.8161192185034317 0.1417734577827763 0.09746517046115395 2.3614575758922025 0.03978342241331987 0.12329535686455242 6.51775069054314e-06 5.185902255683111 -0.8222328935142769 down ERPES(ph)PMVPSEQVVEEAVPLPPQALTTSQDGHR ddPTM_PC-9_Lapatinib_30min_R1 6 ERPESPMVPSEQVVEEAVPLPPQALTTSQDGHR 33 1 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 1 ERPES(0.97)PMVPS(0.03)EQVVEEAVPLPPQALTTSQDGHR;ERPES(0.978)PMVPS(0.022)EQVVEEAVPLPPQALTTSQDGHR;ERPES(0.907)PMVPS(0.093)EQVVEEAVPLPPQALTTSQDGHR;ERPES(0.875)PMVPS(0.125)EQVVEEAVPLPPQALTTSQDGHR;ERPES(0.958)PMVPS(0.042)EQVVEEAVPLPPQALTTSQDGHR;ERPES(0.723)PMVPS(0.277)EQVVEEAVPLPPQALTTSQDGHR 83.74700000000001 6.932200000000001e-10 32457200.0 69491.6 55180.5 134393.2 69136.0 98323.2 126439.29999999999 77840.8 86399.9 139056.7 63207.6 True False 68500.63704080116 55052.732942529794 123343.90986875414 74220.49207093507 92540.02268684865 121031.7858834041 81871.0157460405 90414.35477234202 123394.67011403214 74132.94944116716 0.9240241695113469 0.7426216460768276 1.6638203497709398 1.0011808869123355 1.2482981371230828 1.6326314654384073 1.1043809313295212 1.2196244106555612 1.664505068855512 1.0 16.177827290903537 -5.240522670383809 24.91728220394282 1.3146228552132948 0.8333228130277275 0.3774545191911821 0.24835422988070427 782.675153878487 932367.9041045042 0.06027408612561682 0.15910332975502106 5.74747815946084e-06 5.240522670383809 -0.4813000421855673 ERPES(ph)PMVPSEQVVEEAVPLPPQALTTSQDGHRR ddPTM_PC-9_AZD4547_30min_R2 1 ERPESPMVPSEQVVEEAVPLPPQALTTSQDGHRR 34 2 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 1 ERPES(0.998)PMVPS(0.002)EQVVEEAVPLPPQALTTSQDGHRR 89.583 2.0533000000000002e-11 4871800.0 1104.7 1435.4 5441.8 8848.0 5638.7 3380.1 3713.8 7621.5 4929.7 4401.5 True False 1455.971620812567 1899.364979223113 5369.638176391047 6808.230300237303 4855.863836046855 3168.7418126637285 4044.3210054160963 6443.7722996468865 5190.273877817987 4247.404824712332 0.3427908760524556 0.4471824696747038 1.2642162445051894 1.6029153285850049 1.14325430149591 0.7460418640171275 0.9521863755216716 1.5171081084985372 1.2219870937707271 1.0 12.05236590471339 -5.239891387526921 7.340348174400678 1.1896857213144296 0.3895276025904155 0.6296903754261081 0.24105656611643314 0.1318684310502047 33.12098330057802 0.06803020598661999 0.1732951769733906 5.755838667980387e-06 5.239891387526921 -0.8001581187240141 ERPIS(ph)LGIFPLPAGDGLLTPDAQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ERPISLGIFPLPAGDGLLTPDAQK 24 1 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9;D6RHI8 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 ERPIS(1)LGIFPLPAGDGLLTPDAQK;ERPIS(1)LGIFPLPAGDGLLTPDAQK 62.495 0.0034811 3129700.0 30634.0 23538.2 32675.0 39168.0 41886.0 37080.0 40694.0 35186.0 37058.0 26534.0 True False 35819.731150920394 25874.916937455517 33454.095920627566 36973.54394436931 33678.73898116687 35135.45952439062 36839.16972095354 34262.40478264865 37599.90314315186 31344.404156971585 1.142779137594594 0.8255035510604992 1.0673068070808023 1.1795899440042696 1.0744737342112176 1.1209483947575962 1.1753029196683522 1.0930947869056253 1.1995730706780379 1.0 14.935920284599757 -5.514392763601004 24.568052561004958 1.1246025176370327 0.9747072921854899 0.26460100165055767 0.08987180051161332 322.498869498401 933675.5684369159 0.022007179260814226 0.04070613102741463 3.059195532676199e-06 5.514392763601004 -0.14989522545154277 ERPISLGIFPLPAGDGLLT(ph)PDAQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ERPISLGIFPLPAGDGLLTPDAQK 24 1 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9;D6RHI8 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 ERPISLGIFPLPAGDGLLT(1)PDAQK;ERPISLGIFPLPAGDGLLT(1)PDAQK 132.37 1.2838e-08 13657100.0 26908.0 32834.0 28509.0 33419.0 41370.0 40505.0 57076.0 42751.0 36973.0 39884.0 True False 31462.99294277489 36093.54252765356 29188.76268098458 31546.641775859833 33263.84547702987 38380.84649502273 51669.348085544385 41628.83154842872 37513.66017895605 47114.65347842973 0.6677963355324142 0.7660789130960729 0.6195262094912345 0.6695717668878256 0.7060191049109359 0.8146265261739523 1.0966725693780155 0.8835644215761332 0.7962206534349392 1.0 15.523888212482824 -6.931076852353176 3.6232450938890697 0.9372529721292002 0.6859457579847253 0.6922875355290785 0.08081176830226464 0.1394430300532729 3.6848665091820907 0.030942164861664595 0.026520224558033854 1.1719879532836831e-07 6.931076852353176 -0.2513072141444749 ERPISMINEASNYNVTSDYAVHPMS(ph)PVGR ddPTM_PC-9_AZD4547_30min_R2 4 ERPISMINEASNYNVTSDYAVHPMSPVGR 29 1 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;Q9HAU0-5;Q9HAU0-3;F5H1X3 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 ERPISMINEASNYNVTSDYAVHPMS(1)PVGR;ERPISMINEASNYNVTS(0.002)DY(0.009)AVHPMS(0.989)PVGR;ERPISMINEASNYNVTSDY(0.003)AVHPMS(0.995)PVGR;ERPISMINEASNYNVTSDY(0.001)AVHPMS(0.999)PVGR 84.787 2.8814000000000002e-08 39376500.0 33204.3 26785.899999999998 49433.7 83259.0 70822.8 61921.5 47054.0 71718.0 54403.799999999996 66416.3 True False 43762.57670765518 35443.91834817638 48778.176838594234 64064.923888727106 60990.27671051466 58049.53881626494 51241.714844323586 60635.63101568921 57279.473800441 64091.08555254845 0.6828184657876348 0.5530241537119202 0.7610758410169364 0.9995918049507853 0.9516187186517315 0.9057349913143532 0.7995139168349765 0.9460852549606745 0.8937198255672766 1.0 15.96783608548087 -5.534547456963926 4.4673692910608525 0.9196658521690848 0.6227069255114224 0.801566337153223 0.06237224995495882 0.07970876408015169 3.9678590327061958 0.01726953431511336 0.03328939204004229 2.9204686123659584e-06 5.534547456963926 -0.29695892665766244 ERPISMINEASNYNVTSDYAVHPMS(ph)PVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ERPISMINEASNYNVTSDYAVHPMSPVGR 29 1 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;Q9HAU0-5;Q9HAU0-3;F5H1X3 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 ERPISMINEASNYNVTSDYAVHPMS(0.999)PVGR;ERPISMINEASNYNVTSDY(0.003)AVHPMS(0.997)PVGR;ERPISMINEASNYNVTSDYAVHPMS(0.999)PVGR 92.51799999999999 2.4399000000000002e-09 24091000.0 20329.2 18764.5 32835.6 36666.8 43574.7 40990.3 34195.3 39254.3 33496.2 31045.4 True False 23770.532039997717 20627.315549739764 33618.52523370645 34612.47807136953 35036.550338601235 38840.69650870092 30956.073631467105 38223.91621836881 33986.018556415416 36673.68526474884 0.6481631684516369 0.562455488201699 0.9166933999409369 0.9437960167215437 0.9553594105874809 1.0590889960555734 0.8440949800379738 1.0422709346614278 0.926714026994259 1.0 15.162457626401746 -5.322175960827136 4.681329485773026 0.9642018426080251 0.604163119999243 0.8444080835740486 0.06123296222539332 0.0650511789576093 2.9220248761259775 0.015316195415153862 0.03440305295820525 4.762379928504626e-06 5.322175960827136 -0.3600387226087821 ERPISMINEASNYNVTSDYAVHPMS(ph)PVGR ddPTM_PC-9_Lapatinib_30min_R1 1 ERPISMINEASNYNVTSDYAVHPMSPVGR 29 1 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;Q9HAU0-5;Q9HAU0-3;F5H1X3 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 ERPISMINEASNYNVTSDYAVHPMS(1)PVGR 80.751 5.6982e-07 8966200.0 10924.0 7204.5 9031.8 9194.8 8880.8 7959.6 7353.0 6858.6 9327.6 5539.1 True False 10768.221756783745 7187.818422893159 8289.240267756215 9871.016264953632 8358.448804324575 7619.186462733851 7733.702361494681 7177.275594550294 8277.027464017536 6496.526054613188 1.6575353760241174 1.1064095429570522 1.2759496688033782 1.5194299510188551 1.286602829582933 1.1728093443608159 1.190436595879266 1.1047867020334208 1.2740697712033362 1.0 12.665452743794399 -6.658346862803927 3.554904330928331 1.1562155314026765 1.3653894155002417 0.35834187864406386 0.15075790696546068 0.3038811498914633 7.448226023820824 0.051387767135099606 0.050698519895339904 2.1961051844079456e-07 6.658346862803927 0.2091738840975652 ERPLQQVS(ph)PVASVPWR ddPTM_PC-9_AZD4547_30min_R2 1 ERPLQQVSPVASVPWR 16 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 ERPLQQVS(0.817)PVAS(0.183)VPWR 79.461 0.0041983 36010000.0 27135.0 26256.0 29035.0 43669.0 36048.0 26595.0 31797.0 38953.0 35300.0 34445.0 True False 35763.36555693762 34742.73853593569 28649.976928868036 33601.78672932444 31043.357433773213 24932.010445783217 34626.87140104894 32933.70890089159 37165.88593362167 33239.09103424205 1.0759429468181043 1.0452373231309071 0.8619362334353119 1.0109117212233258 0.9339412260640086 0.7500809940951426 1.0417514535935186 0.9908125606372369 1.1181378544718428 1.0 15.020593309842978 ERPLQQVS(ph)PVASVPWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ERPLQQVSPVASVPWR 16 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 ERPLQQVS(0.952)PVAS(0.048)VPWR;ERPLQQVS(0.929)PVAS(0.071)VPWR;ERPLQQVS(1)PVASVPWR 85.473 0.012598 35217800.0 49328.0 49679.0 52581.0 51088.0 68989.0 72797.0 67089.0 58982.0 53901.0 50057.0 True False 57678.25612759024 54610.80280292685 53834.73045455297 48225.70498953073 55471.10069168035 68979.39716820567 60733.84423770214 57433.784996594775 54689.20015432638 59131.937849006055 0.9754163016756223 0.9235415714326163 0.9104171520984218 0.8155610443999909 0.9380903570812497 1.1665336817532548 1.0270903753025407 0.9712819685235493 0.9248673752917713 1.0 15.85164993687085 -6.538206469746032 24.990761135151512 1.0206842665770413 0.9039011205054271 0.378936432444007 0.06834397478442128 259.0005597379894 422279.1055889585 0.023881594359490506 0.023888991753651834 2.895966476910099e-07 6.538206469746032 -0.11678314607161411 ERPLQQVS(ph)PVASVPWR ddPTM_PC-9_Lapatinib_30min_R1 1 ERPLQQVSPVASVPWR 16 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 ERPLQQVS(0.999)PVAS(0.001)VPWR 95.307 0.0011704 34284000.0 36339.0 34544.0 33249.0 28771.0 33971.0 36738.0 39124.0 31973.0 37543.0 35827.0 True False 35820.79919624355 34464.015490377016 30515.39556485158 30886.915317242467 31972.89256955569 35166.80138046082 41149.64928479776 33458.58230317505 33314.51199468356 42019.64921352327 0.8524773496851389 0.8201880818958716 0.7262172849132389 0.735058856876465 0.7609033670672765 0.8369132546004934 0.9792954023889014 0.7962603907794404 0.7928317493893282 1.0 15.358776497771194 -6.947557981117535 5.355537132156274 0.8795061336492096 0.7769083458667598 0.3516215711044074 0.07153198992376501 0.2510812683159194 15.594753100742853 0.026596208231640186 0.023157720751697013 1.1283452860901961e-07 6.947557981117535 -0.10259778778244977 ERPS(ph)PCNGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ERPSPCNGR 9 1 Q9Y4B6-3;Q9Y4B6-2;Q9Y4B6 Q9Y4B6-3 VPRBP Protein VPRBP 1 ERPS(1)PCNGR 60.691 0.032542 1928400.0 5720.3 6228.9 6355.0 6884.8 9895.1 7159.1 7036.6 6653.6 5456.2 5251.5 True False 6688.633808925041 6847.264026634017 6506.527301471707 6499.066976822764 7956.226187569697 6783.66419312473 6370.042307427668 6478.950050071933 5535.986602883724 6203.5553791488755 1.078193616423026 1.1037644718460558 1.0488384327705316 1.0476358442236446 1.2825268255542335 1.0935123132656623 1.0268373405415838 1.0443930382001105 0.8923893258841608 1.0 12.598879573988459 -7.728699218638885 1.7201743038786994 0.9567722438194739 1.1088493708652158 0.4260643820754074 0.07032457520338535 0.3810783382957639 2.1685366395680585 0.054208532909996866 0.022151067985739518 1.8676727458656345e-08 7.728699218638885 0.15207712704574194 ERPS(ph)SAIYPSDSFR ddPTM_PC-9_AZD4547_30min_R2 1 ERPSSAIYPSDSFR 14 1 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF5;V9GYG5;V9GZ14 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 ERPS(0.838)S(0.162)AIYPSDSFR 156.72 0.0017668 11117000.0 15858.0 15806.0 20562.0 28308.0 30098.0 26435.0 13511.0 22078.0 16250.0 17515.0 True False 20900.514133109154 20914.980396823554 20289.334445027864 21782.027954240217 25919.412229297206 24782.015271076485 14713.452825724818 18666.35240196863 17108.94182496749 16901.805181151078 1.2365847262526397 1.2374406267650024 1.2004241101805246 1.288739736423632 1.5335292267007419 1.4662348196223105 0.8705255248198747 1.1043999266294573 1.0122552970878762 1.0 14.04488971995119 -7.262125828265366 24.999672156397473 1.0054951789735513 1.3249542480756056 0.6787337644459854 0.11127698694064207 43.334378720342166 1578146.9481724985 0.050039946899445374 0.03599033986349307 5.468574987584807e-08 7.262125828265366 0.31945906910205424 ERPS(ph)SAIYPSDSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ERPSSAIYPSDSFR 14 1 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF5;V9GYG5;V9GZ14 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 ERPS(0.855)S(0.143)AIYPS(0.001)DSFR;ERPS(0.5)S(0.5)AIYPSDSFR 120.32 0.00042689 6480000.0 24307.0 25580.4 32088.0 27789.0 43603.0 33774.0 32545.0 24739.0 25387.0 21240.3 True False 28421.69501486655 28119.85305702593 32853.099614417675 26232.072423153575 35059.305156754475 32002.83198427102 29462.101994604433 24089.627463137196 25758.236847514585 25090.99825187771 1.1327446891332664 1.1207147987793413 1.309358012966227 1.0454774321779114 1.3972861822717946 1.2754706553724324 1.1742100373547157 0.9600904364709533 1.0265927480819517 1.0 14.61488224943501 -7.680440520090098 5.038480909104214 0.9953646396865763 1.2147983908585582 0.5067674772811473 0.09640087534049292 0.16883305657846276 7.448159443084131 0.048190060635861225 0.026662489824114035 2.0871779591280222e-08 7.680440520090098 0.21943375117198194 ERPSGPES(ph)PVQGPR ddPTM_PC-9_AZD4547_30min_R2 2 ERPSGPESPVQGPR 14 1 A0A669KBI7;Q9UMN6 A0A669KBI7 KMT2B Histone-lysine N-methyltransferase 2B 1 ERPS(0.139)GPES(0.861)PVQGPR;ERPS(0.082)GPES(0.918)PVQGPR 163.9 0.0026354 12286300.0 11324.8 13325.099999999999 16805.5 23738.0 20330.0 18130.0 14036.3 21116.4 17127.4 21685.7 True False 14925.8508295267 17632.17798846726 16582.648089481376 18265.570848444062 17507.53042134403 16996.328233955617 15285.503508083892 17853.345586598894 18032.71939771989 20926.490243613374 0.7132515130711884 0.842576933981965 0.7924237603361266 0.8728444491076851 0.8366204852095163 0.8121920129030133 0.7304379917577878 0.8531457200305061 0.8617173347175768 1.0 14.35304274500205 -14.522878745280325 0.24102934425873854 2.080424376111543 0.7958637085508871 0.5878411255242213 0.04877823662646745 127.78455767399987 1.2713757321385775 67.56966862663235 0.07763824996818346 3.000000000000087e-15 14.522878745280325 -1.284560667560656 ERPSGPES(ph)PVQGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ERPSGPESPVQGPR 14 1 A0A669KBI7;Q9UMN6 A0A669KBI7 KMT2B Histone-lysine N-methyltransferase 2B 1 ERPS(0.002)GPES(0.998)PVQGPR 82.865 0.0041239 15690000.0 14102.0 18632.0 25505.0 18191.0 27777.0 15912.0 16609.0 19904.0 16987.0 13063.0 True False 16489.190072804042 20481.661825401752 26113.13592825115 17171.817246017734 22334.296248862905 15077.546708524913 15035.67528125319 19381.541090031238 17235.40273875332 15431.218493348893 1.0685604691496755 1.327287396923949 1.6922277355807216 1.1127972333111003 1.4473449558432052 0.977080760992632 0.9743673377273357 1.2559955066662427 1.1169178082846833 1.0 13.913564365301584 -6.762976464757933 24.999991673635414 1.0752154339853552 1.3376092132879405 0.3522550782412318 0.17908354968190063 49.61405114703283 806938.7536473866 0.06230637952280354 0.0578761316086942 1.7259314209546575e-07 6.762976464757933 0.26239377930258523 ERPSGPES(ph)PVQGPR ddPTM_PC-9_Lapatinib_30min_R1 2 ERPSGPESPVQGPR 14 1 A0A669KBI7;Q9UMN6 A0A669KBI7 KMT2B Histone-lysine N-methyltransferase 2B 1 ERPSGPES(1)PVQGPR;ERPS(0.001)GPES(0.999)PVQGPR 107.98 0.0003441 38084000.0 46534.0 43559.0 79354.0 32828.0 42545.0 48501.0 37315.0 41503.0 70992.0 41821.0 True False 45870.41662670952 43458.141811756956 72829.8204352984 35242.280630997724 40042.586746688285 46426.72529135311 39246.988116302775 43431.38089415054 62996.133381098356 49049.70412702028 0.9351823307215553 0.8860021193851999 1.4848167125880427 0.7185013907470975 0.8163675491903691 0.9465240640621472 0.8001472957852679 0.8854565316373694 1.284332586756529 1.0 15.581956813531823 ERPSS(ph)AIYPSDSFR ddPTM_PC-9_AZD4547_30min_R2 1 ERPSSAIYPSDSFR 14 1 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF5;V9GYG5;V9GZ14 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 ERPS(0.035)S(0.953)AIYPS(0.012)DSFR 134.88 0.00014937 10140000.0 21374.0 16922.0 23325.0 38861.0 33466.0 29642.0 13358.0 38861.0 22642.0 27436.0 True False 28170.48739318165 22391.70557225409 23015.695259715732 29902.196846464944 28819.823565209008 27788.481054104395 14546.836122125105 32855.925386941904 23838.80989544087 26475.47399086845 1.0640220229068542 0.8457527740571188 0.8693213676799133 1.1294300852471382 1.0885479736887482 1.0495933354654503 0.549445729551146 1.240994793833497 0.9004110711544964 1.0 14.69236889259252 -5.021613141953553 0.002987022618553177 1.7237662498547777 0.21066705495090576 0.0 0.18337127879957918 1989506.2355457987 1001.2164038502391 248513.72638229543 258726.28039529236 9.514519445365879e-06 5.021613141953553 -1.513099194903872 ERPSS(ph)AIYPSDSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ERPSSAIYPSDSFR 14 1 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF5;V9GYG5;V9GZ14 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 ERPS(0.203)S(0.797)AIYPSDSFR;ERPS(0.19)S(0.809)AIYPS(0.001)DSFR 116.78 0.00067382 12803900.0 50445.0 39069.0 52642.0 55659.0 70877.0 50811.0 47501.0 49739.0 44322.0 42594.0 True False 58984.34216583464 42947.512121974076 53897.18492589671 52540.60667891266 56989.160644801705 48146.381712346614 43001.361402541224 48433.40395282671 44970.125401013975 50315.955026081494 1.1722790938830407 0.8535565329071474 1.0711748370463976 1.0442136426045776 1.1326260351266537 0.9568810069766087 0.8546267556732507 0.9625854051209213 0.893754781712948 1.0 15.618728326043772 -6.982666747571565 22.881969852323053 0.9219281374862577 1.0440002280828116 0.33029419527889436 0.08624891311425853 106.64915708554105 140787.91391154978 0.029398061568378396 0.025917401436873273 1.0407184465638444e-07 6.982666747571565 0.12207209059655388 ERPSS(ph)AIYPSDSFR ddPTM_PC-9_Lapatinib_30min_R1 3 ERPSSAIYPSDSFR 14 1 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF5;V9GYG5;V9GZ14 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 ERPS(0.245)S(0.753)AIY(0.002)PSDSFR;ERPS(0.083)S(0.917)AIYPSDSFR;ERPS(0.035)S(0.769)AIYPS(0.193)DS(0.003)FR 146.27 0.00093331 22816100.0 67024.0 59145.0 75577.0 60943.0 66410.0 69421.0 53622.0 64432.0 75791.0 52773.0 True False 66068.22546930384 59008.053386358 69363.35079565669 65424.95151988829 62503.89436708359 66452.02565825495 56398.28478553893 67425.74594058034 67254.61946538807 61894.74273439765 1.0674287112366783 0.9533613159937186 1.1206662752167544 1.0570356807304209 1.0098417346251833 1.0736295640392832 0.911196691253002 1.08936143785131 1.086596639620762 1.0 15.91752925339741 -6.238609641339485 23.699190544799134 1.0293032874307533 1.0478216780535217 0.02662593629501464 0.06224095195859543 2444.805036681139 2537908.231606392 0.018471466602401784 0.023831564663689856 5.772851137738121e-07 6.238609641339485 0.018518390622768388 ERPSS(ph)REDTPSR ddPTM_PC-9_Lapatinib_30min_R1 1 ERPSSREDTPSR 12 2 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 ERPS(0.01)S(0.84)REDT(0.122)PS(0.028)R 125.84 0.0036943000000000006 7242300.0 8075.3 8074.5 10323.0 7246.3 9029.8 8014.5 7402.1 7551.4 8252.8 8470.1 True False 7960.144741171348 8055.8039913458 9474.282787932358 7779.21707494818 8498.684917269851 7671.738517712001 7785.344519246536 7902.265611741041 7323.282758163295 9934.145499301187 0.8012913382163872 0.8109206767620307 0.9537088810103317 0.783078632731462 0.8555023598021277 0.7722595283360473 0.7836954391088989 0.7954650565865904 0.7371829573744866 1.0 13.278180161856309 ERPSSREDT(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 1 ERPSSREDTPSR 12 2 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 ERPS(0.005)S(0.148)REDT(0.827)PS(0.021)R 183.06 0.0023515999999999997 7172100.0 25447.0 28167.0 36360.0 52480.0 43517.0 35151.0 28948.0 43045.0 28721.0 37632.0 True False 33538.61666951875 37271.43191429388 35877.842642798045 40381.546807917424 37475.41570809778 32953.00241322527 31524.315920293277 36393.38432569704 30239.13342491639 36314.51513428931 0.923559533852912 1.0263508070110792 0.9879752630628147 1.111994657193919 1.0319679491662086 0.9074333580213497 0.8680913349308917 1.0021718365539531 0.8327010098604799 1.0 15.148258697098129 -6.761405636605897 24.99999999890945 0.9188409761419567 1.0206591961537914 0.34110130367219416 0.06531126302161455 0.9984199820707951 739352.5230708697 0.02178510761333091 0.02047021887138237 1.7321853586567235e-07 6.761405636605897 0.10181822001183471 ERPTPSLNNNCTTS(ph)EDSLVLYNR ddPTM_PC-9_Lapatinib_30min_R1 2 ERPTPSLNNNCTTSEDSLVLYNR 23 1 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 ERPTPSLNNNCT(0.008)T(0.064)S(0.794)EDS(0.134)LVLYNR;ERPTPSLNNNCTT(0.061)S(0.899)EDS(0.041)LVLYNR 95.834 4.3721e-06 13851200.0 16842.4 6382.0 16875.0 18694.3 25229.0 20235.7 19467.5 22302.0 22857.1 23737.1 True False 16602.224287482113 6367.22287110891 15487.60263938376 20069.141184356653 23745.079822122418 19370.266282720648 20475.431894790934 23338.232337453806 20282.69270206648 27840.026107302405 0.5963437039711457 0.22870750359816636 0.5563070443860461 0.7208736481426122 0.852911550104262 0.6957704065385144 0.7354674099756053 0.8382977892155143 0.7285443132808829 1.0 14.764872943640475 -5.6781593939974915 2.848898507472299 0.7894826690697284 0.4083546365719268 0.6435851144019633 0.11764551918426619 0.14792718007152506 2.41420144571652 0.03141819524808256 0.059462368920948375 2.098169675745063e-06 5.6781593939974915 -0.38112803249780164 ERQEQEEAR ddPTM_PC-9_Lapatinib_30min_R1 1 ERQEQEEAR 9 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 0 80.102 0.036091000000000005 0.0 4273.1 6993.2 4974.8 7023.6 7040.8 5921.9 14295.0 14696.0 9214.0 7385.8 False True 4212.164810409432 6977.0076750609305 4565.791147283337 7540.138974042758 6626.673986745399 5668.6341416231435 15035.125154027815 15378.829810385667 8176.222292278573 8662.42568904011 0.48625696330518076 0.8054334808191651 0.52707997865541 0.8704419806547612 0.764990572459353 0.6543933933880925 1.7356714728359037 1.7753491184164845 0.9438721422595645 1.0 13.080555355748803 -7.247953436509981 24.53878774923476 1.4283356040395874 0.6951697285200453 0.5907696890505467 0.27465704171061295 390.55582127381643 710649.5564097206 0.1030563172174294 0.07933822814229272 5.649975485670284e-08 7.247953436509981 -0.733165875519542 ERQEQEEARR ddPTM_PC-9_AZD4547_30min_R2 2 ERQEQEEARR 10 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 0 ; 125.71 0.0015 11930600.0 8787.3 6986.5 10086.9 11263.8 13322.900000000001 11225.1 8566.4 7981.0 10681.2 12686.0 False True 11581.478612805524 9244.749496546106 9953.141115336615 8667.104933975232 11473.245304993821 10523.192722502763 9328.793004684268 6747.7198351350535 11245.786425898013 12241.867001317876 0.9460549286770343 0.7551748026302589 0.813041108375473 0.7079888168236258 0.9372136867488178 0.8596068492959372 0.7620400551386479 0.5512002241495223 0.9186332791139921 1.0 13.579535979094635 -8.515001799010525 24.957590598873793 1.0000000436964438 0.7906831308822175 0.2921429616398342 0.10822829428039363 581.818568336153 1843452.5370847492 0.10548903858714352 0.0272371526579172 3.054908458613435e-09 8.515001799010525 -0.20931691281422626 ERQEQEEARR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ERQEQEEARR 10 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 0 ; 104.42 0.010559 11903900.0 3089.85 3152.96 4754.200000000001 6718.8 7664.9 8351.3 4715.4 7901.700000000001 6948.900000000001 6963.0 False True 3612.9005776807244 3465.9650316132843 4867.5581584039055 6342.367418643498 6163.0178679450355 7913.343126376578 4268.72317546037 7694.2887475431935 7050.514516472768 8225.336780922325 0.4392404437542801 0.42137667112332367 0.5917761531289051 0.7710769282242464 0.7492724045341719 0.9620691938998317 0.5189724492936456 0.9354375331341042 0.8571703146338743 1.0 13.005859034904436 -4.759137638666398 0.42028737527493815 0.8909127499669388 6.763935289820675e-23 0.6291209613643816 0.1263333767574394 3.7581935909647566 0.5138353227492034 0.09928144278744577 1.7010071306179393 1.7412549391640043e-05 4.759137638666398 -0.8909127499669388 ERQEQEEARR ddPTM_PC-9_Lapatinib_30min_R1 1 ERQEQEEARR 10 2 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 0 125.71 0.0015 6396500.0 8583.8 10110.0 8626.9 7871.4 8784.3 7635.4 8277.3 9364.1 9909.7 6974.0 False True 8461.393437923865 10086.590916156545 7917.629582797017 8450.289014220647 8267.624744598275 7308.851740986732 8705.858092860053 9799.190271327738 8793.565232232791 8179.446607729119 1.0344701596228187 1.2331629998813467 0.9679908632590499 1.0331125587684131 1.010780452651385 0.8935631090348186 1.0643578362176123 1.1980260696448646 1.075080705817355 1.0 12.997787523514697 -10.671058699446533 12.938410263992232 0.9999999983961132 1.0568420045338378 0.03146282193163774 0.09441977929232194 0.0 0.0 0.09646549251617287 0.023396318521847696 2.1327566292751332e-11 10.671058699446533 0.05684200613772461 ERQEQLER ddPTM_PC-9_AZD4547_30min_R2 3 ERQEQLER 8 1 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;A0A0U1RQP7;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 0 ;; 112.11 0.0048418 8084100.0 30878.4 31152.2 44969.0 59073.0 49939.4 43719.5 34582.6 53108.2 38463.4 39465.0 False True 40697.08888938062 41221.53943552616 44372.68167777739 45454.63251875201 43006.176326791334 40985.71275369127 37660.3844046267 44901.54799502807 40496.49679941259 38083.342362211115 1.068632277658566 1.0824034047082216 1.165146726244464 1.1935568072369402 1.129264756169747 1.0762110206576847 0.9888938855848928 1.1790338034925854 1.0633650905492993 1.0 15.216872481036173 -6.782554023779512 5.582208387428605 1.067605467169278 1.1312147782959405 0.23802875619162422 0.05879017166672102 0.2986851613701237 27.363353193968173 0.02145858725040699 0.01960658913860717 1.6498557558215003e-07 6.782554023779512 0.06360931112666246 ERQEQLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ERQEQLER 8 1 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;A0A0U1RQP7;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 0 91.265 0.011478 3171500.0 6335.4 7568.4 7932.0 7522.7 10109.0 7765.5 7457.8 7923.2 6499.9 5408.0 False True 7407.858090146269 8319.740734186911 8121.128962277519 7101.227507922465 8128.214018063692 7358.263509618537 6751.343194203744 7715.224395324327 6594.948740897316 6388.427590295551 1.1595745565621345 1.3023143201662257 1.2712250154660996 1.111576738963075 1.2723340607962736 1.1518113660388405 1.0568082832244174 1.2076875391127966 1.0323273838018425 1.0 12.641245163120981 -7.767628390757142 0.40050142791925014 0.993052140405926 1.2534857611314836 0.5247006563805563 0.06975085013304785 0.8796638909859273 0.3869878347271973 0.08249565684103394 0.07103611878899395 1.7075428434453184e-08 7.767628390757142 0.26043362072555754 ERQEQLER ddPTM_PC-9_Lapatinib_30min_R1 2 ERQEQLER 8 1 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;A0A0U1RQP7;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 0 ; 111.06 0.0048635 4141000.0 12722.3 12763.6 13839.7 10280.1 16228.900000000001 14472.900000000001 9837.9 11721.099999999999 11789.5 8566.3 False True 12540.87766901591 12734.046668393246 12701.853288786919 11036.132847408298 15274.34800924503 13853.92780497772 10347.258324785604 12265.705095979263 10461.642361061231 10046.973541122743 1.248224414813625 1.2674510006692248 1.2642467143759886 1.0984534598639957 1.5202934442622342 1.3789155259813248 1.0298880834545627 1.2208358114784663 1.0412730080597137 1.0 13.294473362070724 -7.265338698045897 24.989386475281556 1.0914022058511694 1.2946908328669298 0.47306341512885075 0.1147744688456157 352.902841827212 2261620.395500256 0.04850822925558348 0.03410294698852038 5.428268260052327e-08 7.265338698045897 0.20328862701576034 ERRVEWLS(ph)T(ph)TK ddPTM_PC-9_Lapatinib_30min_R1 1 ERRVEWLSTTK 11 2 E9PIP6;Q7Z3Z3 E9PIP6 PIWIL3 Piwi-like protein;Piwi-like protein 3 2 ERRVEWLS(0.922)T(0.607)T(0.471)K 77.64399999999999 0.027132999999999997 0.0 13390.0 11534.0 13270.0 12321.0 14938.0 15027.0 11640.0 11711.0 16017.0 10457.0 True False 13199.056144574733 11507.293731646845 12178.991823681332 13227.127441651119 14059.37620923797 14384.330239647903 12242.662245042586 12255.13581310741 14212.996793512682 12264.478516923351 1.0762019866039791 0.9382619665213086 0.9930297327257691 1.0784908158467106 1.1463492874840049 1.1728448315025737 0.9982211822662772 0.9992382306509772 1.158874939028238 1.0 13.582198271655885 -5.770096147677638 8.649718565138196 1.082529087251423 0.9959730308166038 0.19941376153125345 0.06978885858710626 0.19994283155630285 122.57263908678834 0.020097774009354447 0.03145042658868291 1.697867722955363e-06 5.770096147677638 -0.08655605643481923 ERS(ph)DSGGSSSEPFDR ddPTM_PC-9_AZD4547_30min_R2 1 ERSDSGGSSSEPFDR 15 1 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 ERS(0.652)DS(0.336)GGS(0.005)S(0.006)S(0.002)EPFDR 62.94 0.01941 24901000.0 9431.8 11409.0 11432.0 25464.0 22761.0 12272.0 12899.0 22358.0 16679.0 16529.0 True False 12430.916206372738 15096.736134844998 11280.404210463894 19593.668214878242 19601.0280334585 11504.629900005699 14046.986011325922 18903.084835728532 17560.61788914663 15950.324741036038 0.7793519196754172 0.9464845625371514 0.7072209747204925 1.228418137749185 1.2288795589866677 0.7212787254674056 0.880670847734321 1.1851222556676737 1.1009567625897752 1.0 13.961298176424421 -5.750426090014413 24.990293512099072 1.043830440841233 0.8245657154831249 0.31744231380837606 0.15962543363256124 306.6964946584006 695919.6121122092 0.04672841890144718 0.07996608708091636 1.7765355805497265e-06 5.750426090014413 -0.21926472535810826 ERS(ph)DTFINLR ddPTM_PC-9_Lapatinib_30min_R1 1 ERSDTFINLR 10 1 P17655;P17655-2 P17655 CAPN2 Calpain-2 catalytic subunit 1 ERS(0.993)DT(0.007)FINLR 66.00399999999999 0.022333000000000002 2188000.0 5407.0 4123.6 6894.7 3225.7 5110.8 4464.2 4115.5 4920.1 6458.7 5177.3 True False 5329.895188477637 4114.052057553229 6327.8443803116525 3462.9287386197566 4810.192792219402 4273.276572558474 4328.580452703843 5148.705807708115 5731.253192873845 6072.189406681386 0.8777550948284019 0.6775236709557235 1.0421026019624755 0.5702932676654334 0.7921677783842881 0.7037455992160716 0.7128533322661171 0.8479158772687264 0.9438528361067922 1.0 12.5680010773618 -8.193405789392626 2.3969464118047643 0.989678983386282 0.7663737204225428 0.3136916120684027 0.11991070304519137 0.34945616905134164 3.595544981153 0.10314921167591032 0.030812749716414074 6.406107328643003e-09 8.193405789392626 -0.2233052629637392 ERS(ph)GGEQAQDWDALPPK ddPTM_PC-9_AZD4547_30min_R2 2 ERSGGEQAQDWDALPPK 17 1 V9GYP5;A0A087WWQ2;Q92979 V9GYP5 EMG1 Ribosomal RNA small subunit methyltransferase NEP1 1 ERS(1)GGEQAQDWDALPPK;ERS(1)GGEQAQDWDALPPK 102.24 0.0022286 0.0 28297.0 40415.0 39305.0 41458.0 37802.0 49990.0 36980.0 44947.0 37839.0 39233.0 True False 37294.85738583614 53478.35839159962 38783.790018569205 31900.49861971494 32553.84481001707 46864.11739743198 40271.14836024749 38001.47392930899 39839.09229015044 37859.46461159582 0.9850867614861425 1.4125492512965954 1.0244146454910585 0.8426030042153388 0.859860147099024 1.2378441660022357 1.0637009469994727 1.0037509594805436 1.0522888450447947 1.0 15.208366388909687 -5.480973575915838 24.884496367279244 1.008166041816885 1.203734133024303 0.2225560736297033 0.14095579090865393 643.9004597994333 382365.2681091657 0.0372243317401282 0.07747648160192497 3.3038964255433347e-06 5.480973575915838 0.19556809120741803 ERS(ph)GGEQAQDWDALPPK ddPTM_PC-9_Lapatinib_30min_R1 2 ERSGGEQAQDWDALPPK 17 1 V9GYP5;A0A087WWQ2;Q92979 V9GYP5 EMG1 Ribosomal RNA small subunit methyltransferase NEP1 1 ERS(1)GGEQAQDWDALPPK;ERS(1)GGEQAQDWDALPPK 87.654 0.005313399999999999 0.0 24267.0 38457.0 45430.0 45095.0 48044.0 39159.0 39876.0 38121.0 39188.0 25098.0 True False 23920.948129977227 38367.95517929105 41694.92076487132 48411.43673251013 45218.14637813824 37484.26085408746 41940.58416523352 39892.24082755254 34774.23477206562 29436.15585901712 0.8126383161084388 1.3034295430100418 1.4164526429526632 1.6446249627286285 1.5361430546402906 1.2734088321048544 1.424798277536839 1.3552123116419914 1.1813442943642145 1.0 14.845301658103184 -8.502805010228055 2.4277758630966697 1.0015490908333753 1.364234785605522 0.21431821161514564 0.20764239898757664 0.43626562998420093 5.932842081401525 0.2081180918647424 0.0568149977248577 3.14191903775706e-09 8.502805010228055 0.3626856947721466 ERS(ph)GSESSVDQK ddPTM_PC-9_AZD4547_30min_R2 1 ERSGSESSVDQK 12 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 ERS(0.99)GS(0.006)ES(0.001)S(0.003)VDQK 123.72 0.0016579999999999998 2036800.0 7783.2 8789.0 11509.0 10913.0 9321.2 8889.8 10771.0 8323.7 8159.3 13184.0 True False 10258.095699382968 11629.872371737463 11356.383140152984 8397.176454169265 8027.112275623803 8333.919400673945 11729.598133808158 7037.463424597625 8590.583940458908 12722.432172897285 0.8062998929745434 0.9141233542209554 0.892626738804361 0.6600291783875922 0.6309416443755177 0.6550570902966 0.9219619310524468 0.553153935423574 0.6752312626794356 1.0 13.635086879444984 -5.7543653208766905 24.984113108734896 0.7104266525457115 0.8753273751033976 0.19035716233439426 0.1315545862994189 228.7531290528329 807899.1109298457 0.03469763345601423 0.05849822817520227 1.7604945263653174e-06 5.7543653208766905 0.16490072255768617 ERS(ph)PALK ddPTM_PC-9_AZD4547_30min_R2 1 ERSPALK 7 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 ERS(1)PALK 70.256 0.020974 745860000.0 806720.0 809970.0 812140.0 932630.0 900060.0 1022900.0 910750.0 833580.0 1002700.0 913800.0 True False 1063240.1791816019 1071776.9626733635 801370.4929571514 717626.562489864 775102.2051664975 958937.9012969232 991804.985643465 704769.3647627966 1055700.6749473782 881808.1401390743 1.2057500161133838 1.21543101485129 0.9087810108339024 0.8138125855548164 0.8789918916423841 1.087467735493669 1.1247401112525934 0.7992320922005142 1.197199965494624 1.0 19.75010526924494 -5.253138473244207 24.477548834083958 0.9691043064161017 1.2105905670327155 0.35917452326056365 0.12489703091371111 490.4173389913935 1446121.5043830534 0.03236361702963663 0.08250658455489829 5.582921568950291e-06 5.253138473244207 0.24148626061661382 ERS(ph)PALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ERSPALK 7 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 ERS(1)PALK 61.678999999999995 0.033044 57675000.0 169390.0 225980.0 187470.0 205430.0 260770.0 180950.0 196820.0 162940.0 181840.0 165940.0 True False 198064.38139499907 248413.80095020923 191939.9957839345 193920.42311304595 209673.99045310763 171460.66345573062 178175.7847465982 158662.99764920096 184499.06599251804 196023.60841968266 1.0104108530180056 1.267264708332275 0.979167750922097 0.9892707550708186 1.0696364185083247 0.8746939454794483 0.9089506421345299 0.8094075959947978 0.9412083956617572 1.0 17.580667892547176 -6.087289807037086 0.8623751613560862 0.8957070322533812 1.1292438795538382 0.40167214144683405 0.0910192633335429 0.595047431564293 0.913890522126494 0.043147254025952785 0.08929857077281571 8.179188043810851e-07 6.087289807037086 0.23353684730045698 ERS(ph)PALK ddPTM_PC-9_Lapatinib_30min_R1 2 ERSPALK 7 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 ERS(1)PALK;ERS(1)PALK 68.846 0.022682 114338000.0 357660.0 669450.0 637040.0 565750.0 700420.0 633470.0 704450.0 755460.0 672780.0 620550.0 True False 352559.7028131895 667899.9296558838 584665.0302455133 607357.1422866761 659222.6726787032 606377.9647906937 740922.9740996778 790561.429542322 597004.4317125211 727811.2406691001 0.48441090644473983 0.9176828995411807 0.8033195938386608 0.8344981615402275 0.9057604992094637 0.8331527886725563 1.0180152939359985 1.0862176693170247 0.8202737170748777 1.0 19.47320480746901 -4.501399602277305 2.2147170158605 0.9150775438112871 1.4503709358970062e-25 0.6542297922547464 0.09247592178599569 1.404701540899321 3.619777991505977 0.025555280993885033 3.420410159445484 3.152102981183448e-05 4.501399602277305 -0.9150775438112871 ERS(ph)PFGNPENVR ddPTM_PC-9_AZD4547_30min_R2 1 ERSPFGNPENVR 12 1 Q96HP0;K7ESB7 Q96HP0 DOCK6 Dedicator of cytokinesis protein 6 1 ERS(1)PFGNPENVR 68.168 0.016588 2389800.0 2706.7 4261.3 4455.1 6594.2 5202.2 6718.0 5193.7 5478.7 5094.9 5670.8 True False 3567.374297142549 5638.681890736697 4396.0224630893745 5074.00906937441 4479.964326508402 6297.922397998554 5655.929238469913 4632.092803001427 5364.206012555498 5472.267018057187 0.6519006264444074 1.0304105907351342 0.8033274780970191 0.9272224934622854 0.8186669823905851 1.1508799510727272 1.0335623645203504 0.8464668825034699 0.9802529728273286 1.0 12.417922912588434 -6.717110036767267 24.99999545593155 0.9945956058851767 0.8586413111004605 0.3152693252830018 0.11389808558167058 188.73044930149428 106435.83805706528 0.03693412179925558 0.0369339432850507 1.9181826710318724e-07 6.717110036767267 -0.1359542947847162 ERS(ph)PFGNPENVR ddPTM_PC-9_Lapatinib_30min_R1 1 ERSPFGNPENVR 12 1 Q96HP0;K7ESB7 Q96HP0 DOCK6 Dedicator of cytokinesis protein 6 1 ERS(1)PFGNPENVR 81.44800000000001 0.013841999999999998 0.0 1601.4 5118.7 4139.6 2377.1 1925.0 5232.4 2736.0 1409.6 2014.4 2162.0 True False 1578.563742339206 5106.847964641989 3799.2580673181014 2551.9198637731415 1811.775284695614 5008.622449320141 2877.6566926491837 1475.0951619977968 1787.5170594276055 2535.6988193160823 0.6225359771887142 2.0139804955303746 1.4983080949427665 1.0063970706353187 0.714507287259091 1.9752434363127733 1.1348574486560405 0.5817312177459834 0.7049406048584772 1.0 11.308167682472643 -7.600997577336791 5.725224964608161 0.742157911296908 1.3249811678035335 0.22660934468390248 0.44625254380242724 0.2936644410207172 16.199844456074626 0.2150394909013005 0.12223403572423303 2.5061232331213662e-08 7.600997577336791 0.5828232565066255 ERS(ph)PSPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ERSPSPLR 8 1 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 1 ERS(0.898)PS(0.102)PLR;ERS(0.992)PS(0.008)PLR 66.92 0.022522999999999998 168011000.0 142767.0 135412.0 115675.0 129112.0 173526.0 136316.0 146924.0 114961.0 116657.0 97784.0 True False 166934.63332321757 148854.80845326846 118433.13069988036 121878.27322675196 139524.82596681404 129167.34898939678 133006.2950823558 111943.3955612482 118362.88793163886 115511.4651422821 1.4451780446001148 1.2886583013202668 1.0252932949469515 1.0551184081738336 1.2078872499362145 1.118221025335398 1.15145535483014 0.9691106889117984 1.0246851928147955 1.0 16.817676528528438 -5.039262564307228 3.109986085509076 1.0773884542110521 1.4358061983881236 0.7543388652292735 0.07037451178230388 0.1339958047711526 2.4750877135723686 0.019811942827194628 0.08618494327951176 9.13560756966511e-06 5.039262564307228 0.3584177441770715 ERS(ph)PSPSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ERSPSPSFR 9 1 P49585;C9JEJ2 P49585 PCYT1A Choline-phosphate cytidylyltransferase A 1 ERS(0.991)PS(0.008)PS(0.001)FR;ERS(0.968)PS(0.027)PS(0.005)FR 64.22399999999999 0.02567 23793000.0 9549.5 10807.900000000001 12849.900000000001 8537.6 11866.900000000001 8972.1 9121.1 7301.5 11042.3 9203.2 True False 11166.041738777638 11880.836885077268 13156.290349517121 8059.265951272662 9541.666132254431 8501.587281520642 8257.083376954562 7109.843361578733 11203.772747520796 10871.667307508886 1.0270772111528315 1.0928256493713127 1.2101446795037853 0.7413091040512486 0.8776635508027509 0.7819947981344805 0.7595047883089219 0.6539791147460958 1.0305477927734719 1.0 13.408285592390733 -5.764566947762034 24.99999991671513 0.8170058060587628 1.1082968444714343 0.5336436601336654 0.1169680841134812 55.49334231577054 443587.9511325327 0.031447356755045924 0.04896204710548801 1.719622236018362e-06 5.764566947762034 0.29129103841267145 ERS(ph)PSPSFR ddPTM_PC-9_Lapatinib_30min_R1 2 ERSPSPSFR 9 1 P49585;C9JEJ2 P49585 PCYT1A Choline-phosphate cytidylyltransferase A 1 ERS(0.985)PS(0.015)PSFR;ERS(0.998)PS(0.002)PSFR 74.173 0.013124 21314000.0 7988.0 9163.0 9589.3 7978.9 9859.0 7117.6 12354.4 8757.5 8580.5 6212.700000000001 True False 7874.089655180203 9141.783636473041 8800.90476976845 8565.694922830133 9279.113003539775 6813.19683993598 12994.05038145654 9164.405420825555 7614.073733329309 7286.556917097609 1.0806324227982043 1.2546095145461937 1.2078276296885138 1.175547658556139 1.2734564636099548 0.9350365223867382 1.7832908641619927 1.2577141062772255 1.0449480900180983 1.0 12.831021550238189 ERS(ph)YELVR ddPTM_PC-9_AZD4547_30min_R2 1 ERSYELVR 8 1 A0A3B3ISE6;A0A3B3ITA8;A0A3B3ITJ7;A0A3B3ITE7;A0A3B3IT25;A0A3B3IS40;Q9UGL1;Q9UGL1-2 A0A3B3ISE6 KDM5B Lysine-specific demethylase 5B 1 ERS(0.999)Y(0.001)ELVR 79.48899999999999 0.0097387 2192400.0 6804.8 5223.5 8143.4 11808.0 11111.0 6531.3 7191.7 8914.7 7404.5 7648.6 True False 8968.5848513672 6911.894223890158 8035.4131951969675 9085.848031781423 9568.429439820628 6122.896778512649 7831.747367831048 7537.137954426572 7795.886753413646 7380.824842052652 1.215119589380878 0.9364663668089322 1.0886876964502346 1.2310071335136297 1.2963902605172228 0.829568091580647 1.0610937849668565 1.0211782714966107 1.0562351661559772 1.0 12.849566337945399 -6.757690210838025 24.99999922438592 0.9991561375715117 1.1421763216001044 0.3475770650835903 0.10886292866263866 135.23848299673057 901790.367769407 0.03870499255864598 0.03729166300391329 1.7470679198916909e-07 6.757690210838025 0.14302018402859273 ERS(ph)YELVR ddPTM_PC-9_Lapatinib_30min_R1 1 ERSYELVR 8 1 A0A3B3ISE6;A0A3B3ITA8;A0A3B3ITJ7;A0A3B3ITE7;A0A3B3IT25;A0A3B3IS40;Q9UGL1;Q9UGL1-2 A0A3B3ISE6 KDM5B Lysine-specific demethylase 5B 1 ERS(1)YELVR 90.149 0.0045728999999999995 2573600.0 8383.9 7718.5 8475.8 5760.9 8290.2 7452.4 6239.4 8247.2 6354.8 6903.5 True False 8264.344048581039 7700.628287473226 7778.952441534154 6184.575803799037 7802.586735160308 7133.678224392895 6562.445602381328 8630.395019883821 5639.055504989348 8096.760776664463 1.0206975698725798 0.9510751891876411 0.9607487063164495 0.7638333371072908 0.9636676876570209 0.8810533522186733 0.8105025927522573 1.0659071272992695 0.6964582084778366 1.0 12.983129137584047 -5.548367241505525 24.997361630259107 0.8842299729419566 0.978392888367815 0.14697879345377451 0.10509756601605577 398.9746618211999 391285.1204329427 0.026476692084824054 0.04586083892219763 2.8289987690959417e-06 5.548367241505525 0.09416291542585842 ERSDS(ph)GGSSSEPFDR ddPTM_PC-9_AZD4547_30min_R2 2 ERSDSGGSSSEPFDR 15 1 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 ERS(0.011)DS(0.986)GGS(0.002)S(0.001)SEPFDR;ERS(0.361)DS(0.577)GGS(0.033)S(0.018)S(0.011)EPFDR 99.238 0.0019265999999999999 42586000.0 20950.4 17914.1 32707.4 60384.0 37905.0 28589.0 26410.0 40044.3 25938.3 28685.0 True False 27612.191404609013 23704.482495681194 32273.678505364496 46463.40172350015 32642.545037926477 26801.325310565764 28760.438837050755 33856.3735614708 27309.345583911025 27680.746881034476 0.9975233516378695 0.8563527060002262 1.1659251335980705 1.6785458110357077 1.1792508770885655 0.9682298467505857 1.0390051598194423 1.22310188041449 0.9865826851161332 1.0 14.756595249801096 -6.676801695822767 10.148289169096675 1.0571509132160775 1.1855973897694376 0.08916875090809906 0.2076539497026257 1.1426006914548084 127.99548757432876 0.07652014437386659 0.0764794394335279 2.1047392701040724e-07 6.676801695822767 0.12844647655336017 ERSDS(ph)GGSSSEPFDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ERSDSGGSSSEPFDR 15 1 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 ERS(0.037)DS(0.888)GGS(0.05)S(0.017)S(0.008)EPFDR 50.87 0.045157 13854000.0 4612.8 10751.0 24603.0 4593.9 16039.0 11214.0 18822.0 13982.0 15084.0 10404.0 True False 5393.655933047121 11818.288229116259 25189.628827397097 4336.518676624748 12896.273086924868 10625.918098881248 17039.043900520635 13614.987315153572 15304.574963875613 12290.162841981308 0.438859598720956 0.9616055036103185 2.049576490667251 0.35284468825847176 1.0493166976496993 0.864587250429648 1.386396919194421 1.107795518269853 1.2452703158332075 1.0 13.585216410781788 -7.2478829725599105 24.160450240478525 1.193848669394085 0.9801688295472678 0.06046969699457194 0.4397011108081456 1811.7567603905902 3228946.786229369 0.17040386725867473 0.1311683295582965 5.650892264275952e-08 7.2478829725599105 -0.21367983984681727 ERSDTFINLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ERSDTFINLR 10 1 P17655;P17655-2 P17655 CAPN2 Calpain-2 catalytic subunit 0 98.75399999999999 0.0060111999999999995 2741300.0 21453.0 22032.0 20935.0 27779.0 34608.0 25469.0 26836.0 21457.0 23332.0 23908.0 False True 25084.569183935964 24219.19135558454 21434.169796429625 26222.632690733124 27826.810835606706 24133.36080438795 24293.899804185115 20893.77648557074 23673.186360192656 28242.33114437612 0.8881904633049755 0.8575493018538342 0.7589376984094247 0.9284868361850797 0.9852873225427018 0.8545102272548636 0.8601945668009331 0.7398035374190882 0.8382164432239754 1.0 14.785571554264402 -10.351667481902403 18.04669666459162 0.9999999999972645 0.8564206634321443 0.28516254931715546 0.06801655047839232 0.0 0.0 0.07114726536397396 0.017255746474677272 4.449718302986647e-11 10.351667481902403 -0.14357933656512023 ERSDTFINLR ddPTM_PC-9_Lapatinib_30min_R1 1 ERSDTFINLR 10 1 P17655;P17655-2 P17655 CAPN2 Calpain-2 catalytic subunit 0 93.44200000000001 0.008803 2919700.0 14007.0 11177.0 12050.0 8468.3 12061.0 13560.0 9533.2 8763.9 14331.0 11477.0 False True 13807.257611430787 11151.120343212835 11059.295514345138 9091.087031420675 11351.595692838338 12980.07040990388 10026.78244969415 9171.10278818991 12716.891867879767 13460.784157858787 1.0257394702647928 0.8284153591975171 0.8215937039513711 0.6753757377584159 0.8433086482715018 0.9642878347711821 0.7448884353323674 0.6813200984903662 0.9447363332436532 1.0 13.716474836132267 -5.651926689009953 0.00593121750760336 1.6619875719381185 1.5920322227341423e-06 0.01086619443769199 0.12043758986439261 121579.41067796003 154.09881157046698 20919.69119852793 22269.120167520814 2.228811351555505e-06 5.651926689009953 -1.6619859799058958 ERSDYDRS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 ERSDYDRSR 9 2 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;C9JUL9;A0A087X0F4 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 1 ERSDYDRS(1)R;ERSDYDRS(1)R 88.021 0.029354 70319000.0 17790.4 17700.3 24813.0 31755.0 34941.0 25940.0 23989.0 24994.0 30289.0 31051.0 True False 23447.377136692194 23421.575826768065 24483.963407473817 24434.375359859347 30090.04527556229 24317.967699327553 26123.974527149192 21131.751604982517 31890.014703780937 29963.913941188814 0.7825205072579354 0.7816594278283666 0.8171149955753216 0.8154600699967808 1.0042094412172269 0.8115751415872189 0.8718478693545709 0.7052400312742361 1.0642806799663271 1.0 14.870938463117183 -14.522877813122198 0.025795489576714244 2.09944237826181 0.06753185643641535 0.2959334996126801 0.09352545755252717 2712.0410519168404 5.260951962326264 304.3593921567642 139.54439997295842 3.000006439127218e-15 14.522877813122198 -2.0319105218253948 ERSDYDRS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ERSDYDRSR 9 2 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;C9JUL9;A0A087X0F4 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 1 ERSDYDRS(1)R 112.84 0.0060192 2360200.0 5434.4 3831.9 6299.4 8578.3 11556.0 10029.0 7206.6 10318.0 9137.0 8941.6 True False 6354.3365857074405 4212.305707855138 6449.601586607539 8097.685662223838 9291.684755440101 9503.06158495452 6523.938676734254 10047.163432824671 9270.611339494262 10562.641298333352 0.6015859486499908 0.3987928387305726 0.6106049996817748 0.7666345408796139 0.8796743629745534 0.8996861027983578 0.6176427365533701 0.951198014686912 0.8776792733610148 1.0 13.366683020261794 -5.743744043690189 2.3553021636904363 0.8558664626200118 0.49883071328837336 0.6683046854775969 0.10620125390942045 0.17134343445755473 1.9368163980531896 0.03107245900692964 0.05875387413703171 1.8040806827266366e-06 5.743744043690189 -0.3570357493316384 ERSDYDRS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 ERSDYDRSR 9 2 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;C9JUL9;A0A087X0F4 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 1 ERSDYDRS(1)R 94.402 0.016191 35761000.0 29011.0 23546.0 30548.0 22585.0 20604.0 17278.0 21261.0 22760.0 32537.0 19938.0 True False 28597.29782003416 23491.480683661925 28036.461358690078 24245.9762413514 19392.113229022576 16539.06021698519 22361.79054912805 23817.512689464984 28872.340430200537 23384.256734284954 1.22292951813628 1.0045853050022224 1.1989460121511695 1.0368504125171971 0.8292807186208627 0.7072732909546088 0.9562754464777232 1.0185276769795641 1.2346913890946638 1.0 14.513249953151181 -6.0008084442922085 10.831023729793793 0.9448161699460876 1.1267380784872665 0.25785678198725137 0.13849224899570978 0.13073421067800922 497.8782209703262 0.04266869124751247 0.06071993165514478 9.981402197626972e-07 6.0008084442922085 0.18192190854117885 ERSGSESS(ph)VDQK ddPTM_PC-9_Lapatinib_30min_R1 1 ERSGSESSVDQK 12 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 ERS(0.041)GS(0.024)ES(0.177)S(0.758)VDQK 89.82700000000001 0.043077 0.0 6411.1 7847.6 7569.7 8799.7 8803.9 6302.6 10043.0 12586.0 9827.7 10685.0 True False 6319.676538348252 7829.42936435511 6947.348485887 9446.859292938672 8286.071911133367 6033.052490078187 10562.977399223602 13170.791507451953 8720.800935731075 12531.88801313244 0.5042876645343243 0.6247605593148039 0.5543736489351582 0.7538257031214372 0.661199007080993 0.481416087005886 0.8428879501759373 1.0509822218048863 0.6958888338766159 1.0 13.613316162285166 -7.411856422461711 5.573898278402408 0.912649791973019 0.6071449474824523 0.6316700376835777 0.1132320632972585 0.14920578501826112 6.375161266391976 0.04700631012858121 0.031145178671948843 3.873856932703425e-08 7.411856422461711 -0.3055048444905667 ERSMS(ph)ETGTAAAPGVSSELLSVAAQTLLSSDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ERSMSETGTAAAPGVSSELLSVAAQTLLSSDTK 33 1 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 ERS(0.146)MS(0.342)ET(0.199)GT(0.199)AAAPGVS(0.056)S(0.056)ELLS(0.001)VAAQTLLSSDTK 70.788 2.099e-05 1434100.0 1941.3 1130.2 2813.6 4500.2 9148.8 7530.8 12222.0 8555.8 7180.6 9592.2 True False 2269.9237475772575 1242.3987867684116 2880.68689463742 4248.068383845251 7356.158315210318 7135.871590784282 11064.243680382711 8331.21931561943 7285.602690639433 11331.189928186575 0.20032527580627468 0.109644158701984 0.2542263357065131 0.37490046595001386 0.6491955709710343 0.6297548303407791 0.9764414638272164 0.7352466394456372 0.6429688970719961 1.0 13.468011751153782 -6.207251659947598 1.111571181150674 0.8130334604100256 0.13982394014310165 0.8604480250383029 0.11064833757215517 0.174469904325006 0.4462178802136778 0.04633406749214639 0.07361704299763189 6.205093644356801e-07 6.207251659947598 -0.6732095202669239 down ERSPALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ERSPALK 7 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 0 ; 107.59 0.0041927 3111200.0 48931.0 69732.0 72310.0 74749.0 86538.0 66336.0 67660.0 59863.0 59628.0 61150.0 False True 57214.051868697694 76654.53211726682 74034.14463720217 70561.05586952763 69581.50011823076 62857.223382146025 61250.754984020125 58291.6596800914 60499.94669490686 72236.01093686622 0.7920433468938696 1.061167845830556 1.024892483361346 0.976812741379054 0.963252250723597 0.8701646528776735 0.8479254902039491 0.8069612223055604 0.8375316675194509 1.0 16.140430605140907 -6.765188656896202 3.9108152555340916 0.8571358755650296 0.9746558954584088 0.22391555464368884 0.08170708490964965 0.26724214960140097 9.032183122622248 0.028353099398568022 0.02640948018956404 1.7171622922963453e-07 6.765188656896202 0.11752001989337924 ERSPALK ddPTM_PC-9_Lapatinib_30min_R1 2 ERSPALK 7 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 0 ; 99.375 0.015375999999999999 11031600.0 59020.0 109392.0 99102.0 93632.0 111781.0 94171.0 110477.0 105466.0 101309.0 89688.0 False True 58178.3639770576 109138.70954502441 90954.21610478293 100518.00962719576 105206.26134990147 90143.52585332298 116196.95849188745 110366.33538256203 89898.51358893517 105190.45129825202 0.5530764747087301 1.0375343788152185 0.8646622861888448 0.955581123444292 1.000150299304303 0.8569554055599048 1.104634090431156 1.0492048852384381 0.8546261802227768 1.0 16.682644223839894 -4.755639395833697 24.995071959682587 0.9687885724335611 0.5530758031447705 0.6957744893281743 0.08255965051993126 105.31796623794784 453822.69414291804 0.020205863722754725 0.17599786480891008 1.7553373917781198e-05 4.755639395833697 -0.41571276928879064 ERT(ph)T(ph)KKMATSPLDLCAGACWEM ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ERTTKKMATSPLDLCAGACWEM 22 3 Q494R0 Q494R0 FBXL19-AS1 Putative uncharacterized protein FBXL19-AS1 2 ERT(0.998)T(0.998)KKMAT(0.004)S(0.001)PLDLCAGACWEM 56.148999999999994 0.019466999999999998 0.0 1159.3 2393.0 2856.2 3088.2 4137.5 4537.7 2887.7 3404.1 2382.5 3077.1 True False 1355.5465927812886 2630.561225213955 2924.3026401988204 2915.178166079486 3326.786576292268 4299.735023835688 2614.156150862472 3314.7459819420856 2417.339555252828 3634.953871689804 0.3729198885682494 0.7236848989203456 0.8044951169736251 0.801984913421828 0.9152211262438177 1.1828857189422441 0.7191717537937318 0.9119086786103117 0.6650261985660534 1.0 11.827721340827143 -4.599236970955761 1.2435857031586475 0.8868103483764755 3.245418008278365e-14 0.5564721562118341 0.13720634351466493 1.6418130396380801 1.6462410472856766 0.041254277947071545 2.083530229044349 2.5163035426670945e-05 4.599236970955761 -0.8868103483764431 ERTDVIQGDDVADATSEVEVSSTSET(ph)TPK ddPTM_PC-9_Lapatinib_30min_R1 1 ERTDVIQGDDVADATSEVEVSSTSETTPK 29 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 ERTDVIQGDDVADAT(0.001)S(0.001)EVEVS(0.06)S(0.06)T(0.073)S(0.073)ET(0.366)T(0.366)PK 64.779 0.00016469 3595000.0 6224.8 3954.4 4904.0 5365.3 6474.1 5512.8 8033.8 6944.7 7496.2 3770.8 True False 6136.033210511488 3945.2438297576145 4500.812049987432 5759.882060116124 6093.306166570327 5277.030394964463 8449.7508543147 7267.376114873799 6651.899017514497 4422.577755724831 1.3874336528212905 0.8920688448384364 1.0176897498662019 1.3023811854207 1.3777725351878352 1.1932024005985153 1.910594074547784 1.6432443964306795 1.504077346950861 1.0 12.110671792600428 -6.44503047012123 1.2745258214138544 1.5362679667537866 1.0940343639003394 0.23240955561004506 0.26111994540344535 0.5260841039588994 1.76509548328548 0.11025710753079772 0.13307967117361139 3.588967535485916e-07 6.44503047012123 -0.44223360285344726 ERTDVIQGDDVADATSEVEVSSTSETT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ERTDVIQGDDVADATSEVEVSSTSETTPK 29 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 ERTDVIQGDDVADATSEVEVS(0.106)S(0.019)T(0.019)S(0.106)ET(0.263)T(0.487)PK 114.51 3.387e-06 0.0 4980.4 4306.2 3101.8 7382.4 5713.6 7011.4 5775.3 5873.3 4959.4 4363.4 True False 5823.483352616173 4733.691077315639 3175.7586756420083 6968.788062063731 4594.061095420783 6643.709841135718 5228.221774448887 5719.132098275743 5031.921842736986 5154.449879344603 1.1297972604123252 0.918369794667115 0.6161198090931503 1.3519945338860921 0.8912805833713774 1.2889270429729114 1.0143122732456689 1.1095523736090613 0.976228687934551 1.0 12.331602745486832 -5.763992740260177 24.99999143432452 1.0917065763014044 0.8911230885304656 0.21785237769027777 0.17555759264035561 99.76802333049588 976846.3575630225 0.0469526531417207 0.07343061114568875 1.7218973582721514e-06 5.763992740260177 -0.20058348777093882 ERTDVIQGDDVADATSEVEVSSTSETT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 ERTDVIQGDDVADATSEVEVSSTSETTPK 29 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 ERTDVIQGDDVADATSEVEVSS(0.001)T(0.001)S(0.007)ET(0.229)T(0.762)PK 145.4 4.843e-22 0.0 3364.3 3145.8 3674.9 3811.5 3998.7 5474.4 6424.6 5364.8 3807.6 5077.8 True False 3316.32446506294 3138.5160933773745 3372.763907524229 4091.8104247912675 3763.504327746677 5240.27267344969 6757.234352190769 5614.068193165282 3378.747992194473 5955.490964256803 0.5568515652137825 0.5269953581012672 0.5663284400508066 0.6870651721829776 0.6319385505467444 0.8799060740584356 1.1346225513137047 0.9426709278646135 0.5673332412848541 1.0 12.540004731878515 -6.7457717141649685 3.677887050157747 0.9200481161549919 0.5877244448527698 0.5591137444858295 0.13872001795094852 0.1791239058948763 5.183616921031434 0.051413133257807025 0.04848896206716635 1.7956772721762598e-07 6.7457717141649685 -0.3323236713022222 ERTS(ph)SLTQFPPSQSEER ddPTM_PC-9_Lapatinib_30min_R1 1 ERTSSLTQFPPSQSEER 17 1 B7Z7F3;Q9H6Z4-3;Q9H6Z4-2;Q9H6Z4 B7Z7F3 RANBP3 Ran-binding protein 3 1 ERT(0.104)S(0.438)S(0.438)LT(0.02)QFPPSQSEER 54.953 0.025408 2910700.0 5184.8 4777.8 5883.0 4684.7 8584.4 10216.0 6777.2 8157.6 10140.0 8560.0 True False 5110.863801224126 4766.737297647155 5399.32244903672 5029.228465701077 8079.48246957976 9779.085494659148 7128.090254905717 8536.631876782936 8997.92642106628 10039.584594516966 0.5090712422519336 0.47479427587576367 0.5378033720623774 0.5009398963028557 0.8047626267318172 0.9740528009495445 0.7099985251181272 0.8502973202143389 0.896244893038744 1.0 13.293411956026503 -6.312149920600053 4.085041992266886 0.8674674876109756 0.5035680219695028 0.8494612794354648 0.07600418782865724 0.08338284919889077 2.951175609478262 0.02363779059966359 0.027756132610474868 4.873602219059673e-07 6.312149920600053 -0.3638994656414728 ERTTRLGPRMPQDGS(ph)DDEDEEWPTLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ERTTRLGPRMPQDGSDDEDEEWPTLEK 27 3 F8WBL2;Q13895 F8WBL2 BYSL Bystin 1 ERT(0.003)T(0.018)RLGPRMPQDGS(0.961)DDEDEEWPT(0.018)LEK 49.287 0.033115 0.0 2483.3 3238.4 3160.6 4799.4 3573.5 2531.0 3992.7 976.09 3012.6 2307.2 True False 2903.673642589298 3559.886950159997 3235.96069064225 4530.505177864738 2873.2983275843903 2398.2699044291458 3614.4825513552646 950.4686717528424 3056.6535757207434 2725.47709621485 1.0653817809079842 1.3061518495620372 1.1873006363312908 1.6622796735869532 1.0542368275906024 0.8799449856907143 1.3261834254175418 0.34873478594733226 1.1215113786741528 1.0 11.412293081192258 -6.510261663417004 22.58368785589296 0.9243456006127466 1.30458198772299 0.29267646399599256 0.2717153929156097 207.53659150982497 371477.4675188452 0.08416093470112149 0.09079894485121506 3.088434083249096e-07 6.510261663417004 0.38023638711024343 ERVDDSTGTVIS(ph)DVEEDAGELSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ERVDDSTGTVISDVEEDAGELSR 23 1 S4R403;Q9Y2D8-2;Q9Y2D8-3;Q9Y2D8 S4R403 SSX2IP Afadin- and alpha-actinin-binding protein 1 ERVDDS(0.001)T(0.007)GT(0.014)VIS(0.965)DVEEDAGELS(0.012)R;ERVDDSTGTVIS(1)DVEEDAGELSR 89.684 0.00038977 0.0 10694.2 8578.31 13516.29 15245.93 13412.3 13978.8 13951.78 13685.0 11103.5 7577.72 True False 12504.516839922066 9429.907924724244 13838.569614415273 14391.74997007196 10784.256096001149 13245.727119729014 12630.166396260007 13325.783250456056 11265.867681741769 8951.500650801483 1.3969184975485043 1.0534443656528056 1.54594968533865 1.6077471846894607 1.2047428153887882 1.4797214049851006 1.410955200581832 1.4886647245300615 1.258545144688457 1.0 13.127913844132607 -8.578612891363273 4.927442236177863 1.0000680832356437 1.3949232685649626 0.3861102312552792 0.15402064190505504 0.3359631680793281 25.25132608613035 0.15042323012070996 0.039138142757738525 2.638682328927038e-09 8.578612891363273 0.39485518532931896 ERVPS(ph)VAEAPQLRPAGTAAAK ddPTM_PC-9_Lapatinib_30min_R1 1 ERVPSVAEAPQLRPAGTAAAK 21 2 Q63ZY3-3;Q63ZY3;Q63ZY3-2 Q63ZY3-3 KANK2 KN motif and ankyrin repeat domain-containing protein 2 1 ERVPS(0.999)VAEAPQLRPAGT(0.001)AAAK 47.726000000000006 0.018968000000000002 11620000.0 57637.0 30296.0 52056.0 45857.0 42879.0 65082.0 43757.0 46144.0 57301.0 42011.0 True False 56815.08581066871 30225.851473380695 47776.156621970964 49229.47675446756 40356.94152335755 62298.59457355198 46022.52335535464 48288.01869695399 50847.15797371982 49272.5453738612 1.1530779540528626 0.6134420546784931 0.9696303744704844 0.9991259104016883 0.8190553424253717 1.2643672881287968 0.9340399000326322 0.9800187575162396 1.0319572002605317 1.0 15.588496381408476 -5.501580049865252 24.814027521312777 1.0019973647317173 0.8603290646286064 0.07835687577419459 0.15967841770737878 1426.2796050717243 1661682.9540078165 0.03953672050999136 0.08098588000247965 3.150793567283107e-06 5.501580049865252 -0.14166830010311093 ERVT(ph)PPEGYEVVTVFPK ddPTM_PC-9_AZD4547_30min_R2 2 ERVTPPEGYEVVTVFPK 17 1 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 1 ERVT(0.996)PPEGY(0.004)EVVTVFPK;ERVT(1)PPEGYEVVTVFPK 74.579 0.0068645 5136300.0 49689.0 41167.0 60895.0 83081.0 73849.0 59344.0 57575.0 70511.0 55644.0 57621.0 True False 65489.06840459459 54473.42768543813 60087.49251191381 63927.959038654575 63596.341076528995 55633.21029872381 62699.06346244593 59615.14513158851 58585.228240522505 55603.70632846744 1.177782430864076 0.9796726024637203 1.0806382609993537 1.149706795820648 1.1437428415445314 1.0005306115761796 1.1276058306628722 1.0721433707930246 1.0536209204192675 1.0 15.762893430186853 -8.58762911697745 1.5302094960781318 1.0002560297692957 1.0902761206491804 0.18668295271682733 0.0600030473203649 0.8568554809812925 4.376494016759155 0.05653540768880405 0.016534318435969673 2.584466356176367e-09 8.58762911697745 0.09002009087988472 ERVT(ph)PPEGYEVVTVFPK ddPTM_PC-9_Lapatinib_30min_R1 2 ERVTPPEGYEVVTVFPK 17 1 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 1 ERVT(1)PPEGYEVVTVFPK;ERVT(1)PPEGYEVVTVFPK 111.38 0.00023798 5034400.0 69801.0 54241.0 59543.0 46977.0 60883.0 54884.0 55720.0 52332.0 59852.0 48720.0 True False 68805.6249400642 54115.408297057074 54647.60438262679 50431.84529067808 57301.981640583406 52536.73926085284 58604.90895994611 54763.535767358626 53110.83749049891 57141.18708468063 1.2041336284823312 0.9470473236207101 0.956361027320653 0.8825830869761314 1.0028139869699326 0.919419808044866 1.025615881467361 0.9583898858489162 0.9294668206978458 1.0 15.802243387531687 -4.760102045800731 24.999646237195947 0.9565711469143733 1.2041339279719576 0.7679466262806827 0.04058916150284702 15.197085510024012 283982.03189979336 0.009699653566237077 0.05883467337723076 1.7373925471525733e-05 4.760102045800731 0.24756278105758434 ES(ph)ANKMSPSGGAPQTTPTLR ddPTM_PC-9_AZD4547_30min_R2 1 ESANKMSPSGGAPQTTPTLR 20 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 ES(0.895)ANKMS(0.082)PS(0.021)GGAPQT(0.001)T(0.001)PTLR 53.768 0.041899 20241000.0 46746.0 28774.0 50958.0 97492.0 88572.0 76979.0 59464.0 75754.0 51383.0 80803.0 True False 61610.255622797355 38074.632793761906 50282.26362463429 75016.72563638505 76275.30666400804 72165.4909609304 64756.180802968054 64047.95995374264 54099.00047952641 77974.11156451897 0.7901373210494166 0.48829838557708216 0.644858435905726 0.962072207444302 0.9782132188950268 0.9255057802257576 0.8304830860353714 0.8214003169596454 0.6938072059309414 1.0 16.250707589203834 -5.719641992277027 8.903704926912583 0.8828434712690924 0.6247662139724752 0.5140688636077835 0.10932297936654221 0.24148991883063142 47.414000846517496 0.030425907356676454 0.052463550879111455 1.907032119234825e-06 5.719641992277027 -0.2580772572966171 ES(ph)ANKMSPSGGAPQTTPTLR ddPTM_PC-9_Lapatinib_30min_R1 1 ESANKMSPSGGAPQTTPTLR 20 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 ES(0.939)ANKMS(0.048)PS(0.013)GGAPQTTPTLR 65.374 0.009846200000000001 4037900.0 17914.0 12419.0 10616.0 9984.4 13766.0 15509.0 12308.0 9508.1 17140.0 12297.0 True False 17658.543074974747 12390.24456852108 9743.193458945058 10718.68608298202 12956.310944997318 14845.71622324479 12945.24801649348 9949.881037025578 15209.51270779842 14422.520065277464 1.2243729247767232 0.8590901251960029 0.6755541621607455 0.7431909288022066 0.8983389093137699 1.029342733173669 0.8975718499889247 0.6898850542063129 1.0545669299788778 1.0 13.816035650093928 -6.509108308689634 24.326733192897464 0.9182910090107148 0.8551749132499625 0.017426094528320446 0.1647134064486844 2201.41246431204 3889005.4815112916 0.054405208786964504 0.059168782205078166 3.096646930212029e-07 6.509108308689634 -0.06311609576075228 ES(ph)AQLSGASPK ddPTM_PC-9_AZD4547_30min_R2 1 ESAQLSGASPK 11 0 B7Z673;Q9NYF0-2;Q9NYF0 B7Z673 DACT1 Dapper homolog 1 1 ES(0.884)AQLS(0.111)GAS(0.005)PK 73.632 0.024256 7291300.0 64660.0 85294.0 68474.0 49964.0 59709.0 85083.0 75644.0 88407.0 80074.0 65207.0 True False 85220.53498844968 112863.61748492143 67565.99001988326 38445.571736104925 51419.436002362556 79762.74655982589 82376.16945815488 74745.72954075747 84306.54816568902 62924.122777466146 1.3543380698342948 1.793646260021271 1.073769280166738 0.6109830386045958 0.8171657185307071 1.2676020425729295 1.309134967991238 1.1878708234852784 1.3398128483068843 1.0 15.94132557852536 -5.2787333853537985 23.795847462060124 1.0718489695260114 1.5739921184651875 0.41535373429728906 0.23639214023002167 394.5254312208513 542851.2330671147 0.06851299667582726 0.1432715519702029 5.2634028906334455e-06 5.2787333853537985 0.5021431489391761 ES(ph)ASPTIPNLDLLEAHTK ddPTM_PC-9_AZD4547_30min_R2 2 ESASPTIPNLDLLEAHTK 18 0 O75151 O75151 PHF2 Lysine-specific demethylase PHF2 1 ES(0.442)AS(0.442)PT(0.115)IPNLDLLEAHTK;ES(0.439)AS(0.439)PT(0.122)IPNLDLLEAHTK 122.87 3.0191e-05 32230600.0 89684.2 110310.7 125793.7 178455.0 139264.0 129515.4 112718.5 141588.3 120354.5 122006.5 True False 118201.91005275509 145966.47653168935 124125.59334585648 137314.95685226572 119929.59747162079 121416.78156381981 122750.22813533159 119709.08161045631 126716.19316141833 117735.08957088823 1.0039650072341924 1.2397873655483398 1.0542786674581033 1.1663044327119525 1.0186393700359928 1.0312709830718294 1.0425968042554021 1.0167663866971413 1.0762823014214686 1.0 16.8451848373389 -6.274748139240763 24.889221060902496 1.0323650817384857 1.1205051758016404 0.314106091312193 0.061487557403248516 823.9592594255209 1540914.4353553012 0.017535667095485218 0.019989791043089657 5.311924097779483e-07 6.274748139240763 0.0881400940631547 ES(ph)ASPTIPNLDLLEAHTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESASPTIPNLDLLEAHTK 18 0 O75151 O75151 PHF2 Lysine-specific demethylase PHF2 1 ES(0.626)AS(0.374)PT(0.001)IPNLDLLEAHTK;ES(0.56)AS(0.414)PT(0.026)IPNLDLLEAHTK 130.52 2.3401e-05 41780000.0 162271.0 151558.0 147541.0 179262.0 213560.0 170561.0 176717.0 165563.0 143847.0 160528.0 True False 189740.27530165866 166603.6766280723 151058.93699235827 169218.5313152453 171714.45105328775 161616.48090451956 159977.0864397142 161217.14667849883 145950.49024321247 189630.4556610513 1.0005791244883346 0.8785702488943156 0.7965963930517764 0.8923594615925481 0.9055214810020448 0.8522706985073938 0.8436254919181335 0.8501648435980194 0.7696574357448513 1.0 17.532831161788067 -6.780581685436117 23.484464367818486 0.8525590794332987 0.8882447834929591 0.03323839273056006 0.07079871216828093 407.56937959872886 500014.7287961549 0.024559659075786604 0.0217023231924303 1.657365577505057e-07 6.780581685436117 0.03568570405966043 ES(ph)ASPTIPNLDLLEAHTK ddPTM_PC-9_Lapatinib_30min_R1 1 ESASPTIPNLDLLEAHTK 18 0 O75151 O75151 PHF2 Lysine-specific demethylase PHF2 1 ES(0.549)AS(0.432)PT(0.018)IPNLDLLEAHTK 96.633 0.00046610000000000005 7056000.0 20216.0 16140.0 23643.0 16576.0 19241.0 20797.0 19577.0 18565.0 23291.0 16086.0 True False 19927.716132839654 16102.628821638647 21699.163804619264 17795.05433591502 18109.28220926147 19907.56079017486 20590.60126900332 19427.597674864584 20667.722314896917 18866.44366675231 1.056251855666767 0.8535063155551547 1.1501459516113766 0.9432119084146546 0.9598672929108966 1.055183538657965 1.091387525529755 1.0297434968679962 1.0954752617908026 1.0 14.20353487944171 -6.794793115148105 14.620152456813631 1.0585408727573655 0.9908813994759993 0.13896095013725596 0.07645606842116195 4.453874747130206 1949.6564347721758 0.025691432289287806 0.022690853821747462 1.6040093105980388e-07 6.794793115148105 -0.06765947328136623 ES(ph)CGSSVLTDFEGK ddPTM_PC-9_AZD4547_30min_R2 2 ESCGSSVLTDFEGK 14 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 ES(0.997)CGS(0.003)SVLTDFEGK;ES(0.81)CGS(0.146)S(0.044)VLTDFEGK 164.66 1.2605e-05 5932000.0 39961.0 46257.0 45157.0 41462.0 44801.0 50388.0 48331.0 49394.0 54633.0 42345.0 True False 52667.766759564554 61208.67064506308 44558.18867494035 31903.57648151434 38581.154471551075 47237.230394514925 52632.36537044677 41761.29226120293 57520.78884451994 40862.5144388149 1.2889017595436065 1.497917381876079 1.0904416746467998 0.780754119506886 0.9441698583996881 1.1560040061960737 1.2880354058792771 1.021995166835213 1.4076664061054822 1.0 15.318490361319977 -5.275761959413463 23.23682245520538 1.080648471516549 1.3934095368243897 0.3374973824803451 0.17206848447472328 315.2449175231616 511451.8465819187 0.047360696465776966 0.09949658140723576 5.29953836612671e-06 5.275761959413463 0.31276106530784076 ES(ph)CGSSVLTDFEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESCGSSVLTDFEGK 14 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 ES(0.94)CGS(0.039)S(0.02)VLT(0.001)DFEGK;ES(1)CGSSVLTDFEGK 98.25299999999999 0.0024995 4835100.0 36634.0 47602.0 37334.0 34165.0 38797.0 27866.3 34972.5 25975.7 25582.7 22089.3 True False 42835.4126455186 52327.61196934169 38224.18414998346 32250.84581442449 31195.006356594815 26404.942172182495 31659.651621026376 25293.865398529142 25956.798589786576 26093.915231197403 1.6415862574085995 2.0053568621538163 1.464869637664927 1.2359527318409456 1.1954896794981016 1.0119195198661959 1.2132963313675014 0.9693396017585074 0.9947452637829185 1.0 14.671425807447669 -5.664796872815826 1.6612996044067345 1.0664350759528811 1.8382348556276609 0.8575691004967642 0.12125580376632682 0.12597734390152612 0.6953016757411268 0.036620071174965234 0.08902800544888931 2.1637303018960065e-06 5.664796872815826 0.7717997796747798 ES(ph)CGSSVLTDFEGK ddPTM_PC-9_Lapatinib_30min_R1 1 ESCGSSVLTDFEGK 14 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 ES(0.996)CGS(0.002)S(0.002)VLTDFEGK 135.04 3.3466e-05 3223900.0 9262.4 11224.0 12599.0 12214.0 16762.0 14098.0 12758.0 15019.0 15003.0 14008.0 True False 9130.316477483866 11198.011517600502 11563.158853546427 13112.258304709585 15776.092115359945 13495.061404043145 13418.54681462657 15716.837569555133 13313.204151406058 16429.26413551327 0.5557349618445723 0.6815893533171115 0.7038147757665947 0.7981038101619116 0.9602433794498783 0.8214038859398703 0.8167466725196307 0.9566367330830012 0.8103347807664996 1.0 14.00398024317155 -5.369972099592503 0.9112396277645883 0.8907269419347954 0.528224486573218 0.7423132284440581 0.066749931253398 0.536510588992973 0.6255269726050204 0.02507544583512119 0.16197547113189437 4.266069244565361e-06 5.369972099592503 -0.36250245536157744 ES(ph)CGSSVLTDFEGKDVATK ddPTM_PC-9_AZD4547_30min_R2 1 ESCGSSVLTDFEGKDVATK 19 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 ES(0.969)CGS(0.014)S(0.016)VLT(0.001)DFEGKDVATK 72.145 0.0027415 4165600.0 10625.0 6580.0 8606.6 14654.0 15270.0 9122.3 10579.0 10912.0 9654.0 10665.0 True False 14003.528986270954 8706.856321086861 8492.470860547459 11275.746702043109 13150.024079386281 8551.881138919653 11520.510505761447 9225.801132814648 10164.290730968378 10291.621596173358 1.3606727429113563 0.8460140357593651 0.8251829686106161 1.0956239108359433 1.2777407288542106 0.8309556525182992 1.1194067327587147 0.8964380439565516 0.9876277160003314 1.0 13.3291826974897 ES(ph)CGSSVLTDFEGKDVATK ddPTM_PC-9_Lapatinib_30min_R1 1 ESCGSSVLTDFEGKDVATK 19 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 ES(0.993)CGS(0.005)S(0.001)VLTDFEGKDVATK 57.248000000000005 0.012676999999999999 3607500.0 21826.0 15168.0 14017.0 14682.0 14787.0 16410.0 12662.0 12742.0 14862.0 12389.0 True False 21514.757237601807 15132.879427919133 12864.576367184709 15761.763257716237 13917.257732360556 15708.182553578374 13317.576404358178 13334.039836957953 13188.08505620188 14530.422142695164 1.4806697992885125 1.04146178819222 0.8853546194906717 1.0847422809143987 0.9578013354111077 1.0810547965721218 0.9165305917180998 0.9176636236725809 0.9076188514476082 1.0 13.826788996789027 -4.768784358902168 3.8915596754005737 0.9711103191536147 1.5363395009158825 0.8429283376145571 0.06587442531335887 0.09191540431246795 2.534500176476806 0.01658652351882608 0.151239400377357 1.703003894388032e-05 4.768784358902168 0.5652291817622678 ES(ph)EELLK ddPTM_PC-9_AZD4547_30min_R2 4 ESEELLK 7 0 O43303-2;O43303 O43303-2 CCP110 Centriolar coiled-coil protein of 110 kDa 1 ES(1)EELLK;ES(1)EELLK;ES(1)EELLK;ES(1)EELLK 87.30799999999999 0.018029 92421700.0 193253.0 208100.0 211872.0 227300.0 246915.0 267281.0 207186.0 269936.0 258911.0 213027.0 True False 254703.43408788866 275364.25538270146 209062.43884529444 174899.49674999318 212635.1143131414 250567.87681742388 225625.15262753444 228223.59371219296 272596.5068827173 205568.9895703719 1.2390168119238467 1.3395223470144886 1.0169940479944162 0.8508068124259583 1.0343734955235093 1.218899199441984 1.0975641467085033 1.110204385346097 1.3260585045070723 1.0 17.64926312239605 -5.259083839351936 24.96415674433069 1.0813053493562257 1.289269590028394 0.31299973350436794 0.12290852306359068 251.62066443205225 2666651.3192931535 0.03401431905504607 0.08163897793870711 5.507013747616346e-06 5.259083839351936 0.20796424067216823 ES(ph)EELLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ESEELLK 7 0 O43303-2;O43303 O43303-2 CCP110 Centriolar coiled-coil protein of 110 kDa 1 ES(1)EELLK;ES(1)EELLK;ES(1)EELLK;ES(1)EELLK 101.46 0.011192 102637000.0 216542.0 282571.0 221270.0 308136.0 287418.0 235074.0 251112.0 224442.0 193656.0 224295.0 True False 253198.28370054785 310622.7814333184 226545.9159711483 290872.1389103909 231100.50614737681 222746.30561587383 227324.85346655687 218550.63531595652 196487.8526388418 264957.90798175684 0.9556170096194349 1.1723476524984704 0.8550260594099598 1.0978050858192099 0.872215922550569 0.840685629323472 0.8579659131449999 0.8248503959768749 0.7415813860229097 1.0 18.015403661398388 -6.389910839685191 5.697635948585348 0.8439377732591539 1.0186563552656194 0.40041637514007555 0.09808640239397004 0.21947761451511572 9.269529298159586 0.029063738172613218 0.03295461996310329 4.074639212397067e-07 6.389910839685191 0.1747185820064655 ES(ph)EELLK ddPTM_PC-9_Lapatinib_30min_R1 4 ESEELLK 7 0 O43303-2;O43303 O43303-2 CCP110 Centriolar coiled-coil protein of 110 kDa 1 ES(1)EELLK;ES(1)EELLK;ES(1)EELLK;ES(1)EELLK 99.13600000000001 0.011939 102125000.0 175641.0 131891.0 150742.0 143125.0 184816.0 164503.0 164390.0 185193.0 197284.0 213263.0 True False 173136.327131385 131585.6144928591 138348.5746409471 153650.88995100372 173945.48624223625 157467.59016522253 172901.30983355234 193797.74286028554 175063.79842738053 250125.22539491506 0.6921985851607945 0.5260789441972621 0.553117241263902 0.6142958580383447 0.6954336011795653 0.6295550155591135 0.6912589866158592 0.774802871458903 0.699904610384569 1.0 17.93229103662172 -9.647651040303181 0.2504997200985606 1.1476397388174322 0.5546753815090644 0.8140230377824347 0.05426953292214248 3.095928097469401 0.2937986726327198 0.5014883420950315 0.10273307947227521 2.2508624685636544e-10 9.647651040303181 -0.5929643573083678 ES(ph)EPAPASVTALTDAR ddPTM_PC-9_AZD4547_30min_R2 1 ESEPAPASVTALTDAR 16 0 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 1 ES(0.511)EPAPAS(0.447)VT(0.002)ALT(0.039)DAR 105.58 0.0011152 1607700.0 3884.5 3483.2 5059.7 4645.7 5472.5 3796.0 3860.0 5407.9 4303.4 5487.3 True False 5119.690197380659 4609.076282311513 4992.605072050749 3574.705640349504 4712.737837226026 3558.6355199170193 4203.532522189168 4572.23331617928 4530.868938434778 5295.191297204132 0.9668565137738956 0.8704267747125796 0.9428564128904751 0.6750852688243677 0.8900033205059765 0.6720504171012639 0.7938395963916618 0.8634689588256095 0.8556572716885759 1.0 12.370467089473184 -5.6625222120655865 22.63250757433756 0.811016003178355 0.9210937025308314 0.199518483104704 0.09482617444048881 10.052439517469608 2285.09061427708 0.024472434342301636 0.042387477129833484 2.1750927856819485e-06 5.6625222120655865 0.11007769935247647 ES(ph)GAPSPITFTSLR ddPTM_PC-9_Lapatinib_30min_R1 1 ESGAPSPITFTSLR 14 0 Q8NEV8-2;Q8NEV8;E9PPH6 Q8NEV8-2 EXPH5 Exophilin-5 1 ES(0.894)GAPS(0.095)PIT(0.01)FTSLR 175.6 0.00011372 6505200.0 31481.0 30936.0 38057.0 26365.0 29824.0 28930.0 27422.0 22647.0 28622.0 31819.0 True False 31032.075167091654 30864.369592702187 34928.10036426828 28303.970051061722 28069.81095624 27692.73133912385 28841.776983123516 23699.26229693821 25398.288956978202 37318.87175384757 0.831538406942655 0.8270445525867238 0.9359366648233999 0.7584358454819468 0.752161296337851 0.7420570354265529 0.7728469706523198 0.6350476631034491 0.6805749413997126 1.0 15.187617749990627 -5.881444019351394 8.000831680295244 0.7459005391282684 0.8606998060851776 0.18105770993192738 0.09464156042929622 0.33812992334551784 22.209729334881064 0.02561998425204527 0.0381466192635112 1.3138808435579695e-06 5.881444019351394 0.11479926695690923 ES(ph)GNSQELAR ddPTM_PC-9_AZD4547_30min_R2 1 ESGNSQELAR 10 0 Q86W50 Q86W50 METTL16 Methyltransferase-like protein 16 1 ES(0.764)GNS(0.236)QELAR 85.973 0.027293 0.0 6486.5 6222.4 6424.5 8844.7 8446.9 8710.1 7482.9 8845.1 6260.2 6278.8 True False 8549.072072418492 8233.669114336008 6339.30693230627 6805.69106425281 7274.193739107271 8165.456070081458 8148.863603701893 7478.293035177678 6591.101391548398 6058.981123117977 1.4109751951197866 1.3589197502069335 1.0462661631538532 1.1232401827901013 1.2005638557533482 1.3476615794240137 1.3449230882416834 1.2342492711595239 1.0878233910318884 1.0 12.564859495487463 -8.382027050938936 2.8251680645139894 1.0044603827229668 1.2551642608450913 0.4003431298650332 0.10770913535372331 0.2929826600442033 4.4215678659941275 0.11398876070553592 0.03104607686335928 4.1492819716001245e-09 8.382027050938936 0.25070387812212447 ES(ph)GSPYSVLVDTK ddPTM_PC-9_Lapatinib_30min_R1 1 ESGSPYSVLVDTK 13 0 Q9Y2D9;D6RF85 Q9Y2D9 ZNF652 Zinc finger protein 652 1 ES(0.629)GS(0.249)PY(0.001)S(0.121)VLVDTK 84.566 0.0085239 3923400.0 23814.0 17312.0 24020.0 17787.0 22623.0 19586.0 18725.0 17723.0 20839.0 15888.0 True False 23474.40799304726 17271.915127646116 22045.168319881348 19095.11531569258 21292.359618529306 18748.352437195983 19694.488877871336 18546.47528099244 18491.892375601594 18634.21963057073 1.2597473067525655 0.926892323374269 1.1830475736002768 1.0247338334665606 1.1426483126558042 1.0061249040146554 1.056899042102153 0.9952912248906662 0.9923620490800893 1.0 14.185666782266367 -7.150195258942415 0.8297713743862053 0.9902882350909362 1.1021179134945531 0.22160329299080916 0.08648522799420945 1.021679521624019 1.4112892151768675 0.061781225852587246 0.04037669079957129 7.076275632673209e-08 7.150195258942415 0.1118296784036169 ES(ph)HSPFGLDSFNSTAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESHSPFGLDSFNSTAK 16 0 Q7LBC6;Q7LBC6-2;Q7LBC6-3 Q7LBC6 KDM3B Lysine-specific demethylase 3B 1 ES(0.5)HS(0.5)PFGLDSFNSTAK 84.249 0.011563 0.0 17304.0 16127.0 19850.0 22449.0 22971.0 16596.0 16962.0 19415.0 14054.0 15826.0 True False 20233.2254304213 17727.981980370012 20323.299281544212 21191.25531063999 18469.99744870324 15725.676544411737 15355.236565754498 18905.37682189291 14259.513162444167 18695.128521452923 1.0822726041815325 0.9482674569488465 1.0870906427962204 1.1335174982254188 0.9879577681163657 0.8411643988628535 0.821349612447657 1.0112461543229685 0.7627395097113762 1.0 14.190374768724961 -6.567333563175921 5.046743168215956 0.8850734350446728 1.0572102061588338 0.49685950373806165 0.08333947247869879 0.16455676839553338 9.622451894248503 0.027050007167657743 0.027436351258498522 2.7081108478034455e-07 6.567333563175921 0.17213677111416092 ES(ph)HTPVSIQEEIVGDFK ddPTM_PC-9_AZD4547_30min_R2 2 ESHTPVSIQEEIVGDFK 17 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;A0A0A0MR81;F5H176 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 ES(0.518)HT(0.451)PVS(0.031)IQEEIVGDFK;ES(0.582)HT(0.418)PVSIQEEIVGDFK 139.49 4.5279e-05 3314500.0 40629.0 47991.0 49765.0 44370.0 48597.0 62745.0 52191.0 65915.0 52921.0 46659.0 True False 53548.17686430139 63503.152234844994 49105.08358412663 34141.18200966647 41850.14539528066 58821.54523108359 56835.89789263593 55729.35132601519 55718.29601963724 45025.48261189428 1.1892860166734935 1.4103824890056704 1.09060649071543 0.7582635438680999 0.9294768865892223 1.306405657838409 1.262305134684369 1.2377291278893097 1.2374835934555481 1.0 15.458454119491218 -6.778644284998894 24.978889715758875 1.226987788072298 1.0774054434228761 0.12216862685132712 0.17510089913085658 548.7063745262599 796632.49647446 0.06901722905635192 0.06101067903288251 1.6647756500030168e-07 6.778644284998894 -0.14958234464942177 ES(ph)HTPVSIQEEIVGDFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESHTPVSIQEEIVGDFK 17 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;A0A0A0MR81;F5H176 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 ES(0.552)HT(0.448)PVSIQEEIVGDFK 92.8 0.0011247 1281700.0 9690.0 13627.0 12524.0 14285.0 15429.0 11516.0 14209.0 11839.0 10279.0 10171.0 True False 11330.32561377615 14979.798502294425 12822.619657534498 13484.65776259487 12405.79820800324 10912.080687240637 12863.020655748474 11528.238794457386 10429.310929042525 12014.9217864083 0.9430211711068656 1.2467662102669779 1.067224563379172 1.1223258879511964 1.0325325814469397 0.908210713413446 1.0705871319361873 0.95949345317408 0.8680298644008259 1.0 13.552539636529243 -6.502436590342849 4.472999085277848 0.9653339796436033 1.102236379540871 0.3498111590466516 0.08548194483219182 0.22214332991408128 10.922136917418488 0.026953554212935018 0.0290724352288126 3.144585515508307e-07 6.502436590342849 0.1369023998972676 ES(ph)KEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESKEHR 6 1 E9PRH8;E9PL66;E9PNN9;Q9NX95-3 E9PRH8 SYBU 1 ES(1)KEHR 60.76 0.04361 13528000.0 22454.0 28623.0 30587.0 26635.0 32193.0 20247.0 24746.0 23206.0 21566.0 22096.0 True False 26255.018713284797 31464.50227718304 31316.310081843476 25142.727301835075 25885.012749384146 19185.211677193573 22401.87973447477 22596.867088789426 21881.3619511364 26101.829888160228 1.0058688921727306 1.2054519706856 1.1997745068459178 0.9632553506618247 0.9916934123122751 0.7350140491834242 0.8582493959412496 0.865719652055481 0.8383075839852046 1.0 14.671863331096848 -6.1313268238316185 1.8760765700248991 0.8571395754499724 1.1401163542532817 0.6139221359503144 0.08933776344885032 0.20709091339918606 1.4414617007200927 0.029286041300116694 0.04254762241150816 7.390489021118246e-07 6.1313268238316185 0.2829767788033093 ES(ph)LVKGR ddPTM_PC-9_AZD4547_30min_R2 1 ESLVKGR 7 1 H3BS51;Q9NY59-2;Q9NY59 H3BS51 SMPD3 Sphingomyelin phosphodiesterase 3 1 ES(1)LVKGR 56.81 0.042327 4648800.0 12825.0 11236.0 14572.0 14389.0 14062.0 13618.0 11478.0 11704.0 15952.0 17671.0 True False 16903.083223428224 14867.817268044371 14378.765758824344 11071.838357833922 12109.734027788474 12766.464307226013 12499.519764167677 9895.415731164096 16795.19015334655 17052.34366863378 0.9912469248740214 0.8718928938426426 0.8432134631014248 0.649285433896078 0.710150713773334 0.7486633248372041 0.7330089052309797 0.5802965224871584 0.9849197552967314 1.0 14.057682415968946 -5.1042509515085435 1.7563562952854024 0.7514889545830757 0.9944351210090875 0.19402959980928702 0.12782193803216352 0.6838874510958086 3.2624698375796735 0.03428911198706956 0.2248542484988059 7.865911367279843e-06 5.1042509515085435 0.24294616642601174 ES(ph)MIPITR ddPTM_PC-9_AZD4547_30min_R2 1 ESMIPITR 8 0 J3KRX3;J3KS56;I7HAS0;Q8IYD9;Q8IYD9-2 J3KRX3 C18orf54;B9838V3;LAS2 Lung adenoma susceptibility protein 2 1 ES(1)MIPITR 65.803 0.044721 3127200.0 1846.4 2098.6 2588.1 6516.8 5010.8 4277.6 5412.0 6290.1 2416.5 4686.9 True False 2433.5167924941816 2776.931409640258 2553.7801029655 5014.452443556335 4315.136912703916 4010.1209957842557 5893.657515566777 5318.109577118531 2544.2312566174733 4522.813057581328 0.5380538088822882 0.6139832388131651 0.564644187246419 1.1087021240355934 0.9540825273489257 0.8866431012580375 1.3030955382264986 1.1758411213136686 0.5625329245816885 1.0 12.143004650634932 -5.754592922397388 24.995199535705048 1.012181437478109 0.576402554321669 0.5243856932063612 0.18580111692702814 125.20586744003606 457098.8510197781 0.05121721963498699 0.08623930517296505 1.759572142427894e-06 5.754592922397388 -0.4357788831564401 ES(ph)MIPITR ddPTM_PC-9_Lapatinib_30min_R1 2 ESMIPITR 8 0 J3KRX3;J3KS56;I7HAS0;Q8IYD9;Q8IYD9-2 J3KRX3 C18orf54;B9838V3;LAS2 Lung adenoma susceptibility protein 2 1 ES(1)MIPITR;ES(1)MIPITR 93.195 0.0065221 7329500.0 15566.4 20925.5 20399.0 16365.9 21707.4 22415.0 14771.599999999999 13962.4 18700.8 17236.5 True False 15344.420281471854 20877.048290408893 18721.872962417136 17569.50288104195 20430.61341039044 21456.36270191708 15536.401170006098 14611.144076247196 16594.518975845785 20215.806058807433 0.7590308413542947 1.0327091697297608 0.9261007405767313 0.8690973206773238 1.0106257129178098 1.0613656779007916 0.7685274148758142 0.7227584214917588 0.8208685286934696 1.0 14.30319610845512 -7.283337286857874 24.989531394406995 0.8049351159963063 0.946150978055182 0.20815527497924968 0.10614126836154524 1054.63957966687 1203532.154181846 0.04329594114912626 0.029218140065314376 5.207900919156331e-08 7.283337286857874 0.1412158620588757 ES(ph)MLPAGAESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESMLPAGAESK 11 0 D6RC11 D6RC11 CLDND1 1 ES(1)MLPAGAESK 68.016 0.038263 7586000.0 45075.0 59098.0 54841.0 59991.0 53546.0 47339.0 61511.0 47106.0 48130.0 40521.0 True False 52705.30722816919 64964.85887492444 56148.61742565066 56629.898763446196 43054.04568317724 44856.45950445333 55684.23277892498 45869.51741293264 48833.81019698577 47867.1365359405 1.1010749972185196 1.357191250120974 1.1730097409000453 1.1830642662513617 0.8994489497162754 0.9371034649372301 1.1633082070224756 0.9582674196208086 1.020194933956817 1.0 15.546747884605258 -6.129021401725714 5.602820865990787 1.0002216718124404 1.2177245804121077 0.5685731725407233 0.0884409186977763 0.1687907387823818 6.991917930045953 0.026288882509336697 0.034294045391271906 7.429825233398938e-07 6.129021401725714 0.21750290859966737 ES(ph)MS(ph)TVPADFETDES(ph)VLMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESMSTVPADFETDESVLMR 19 0 E7EUV9;F8W8D3;Q14493;H0YAE8;Q14493-2;H7C4H8 E7EUV9 SLBP Histone RNA hairpin-binding protein 3 ES(0.666)MS(0.666)T(0.666)VPADFET(0.029)DES(0.973)VLMR 41.412 0.045962 0.0 8824.8 9784.4 8193.5 7999.8 11789.0 8176.8 11315.0 9875.5 9365.1 8142.9 True False 10318.664342255079 10755.73056915312 8388.864114021782 7551.59714170153 9479.030078044598 7747.994213566275 10243.16128649405 9616.278588957168 9502.046870471457 9619.143310839067 1.0727217600165886 1.1181588860448022 0.8721009598192618 0.7850592196908243 0.9854339177339643 0.8054765339482635 1.0648725105230346 0.9997021853413214 0.9878267287861631 1.0 13.231692696719835 -10.090128203101491 13.725021694247825 1.0000000227536874 0.9619077125240949 0.008097039216742319 0.10665879605815086 0.0 0.0 0.10936426315130578 0.02652472992003995 8.125906051864604e-11 10.090128203101491 -0.038092310229592474 ES(ph)NRLSAPSYLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESNRLSAPSYLAR 13 1 H0YJH0;Q9H4B6 H0YJH0 SAV1 Protein salvador homolog 1 1 ES(0.942)NRLS(0.058)APSYLAR 54.236999999999995 0.038761000000000004 13824000.0 16424.0 8968.7 23980.0 24530.0 21095.0 18476.0 23532.0 20648.0 15285.0 15727.0 True False 19204.258811213567 9859.053263926613 24551.774144656447 23155.66362733302 16961.586181724553 17507.08603486088 21302.87860307364 20106.011878364385 15508.514208620967 18578.18060513649 1.033699651186725 0.5306791592498991 1.3215381347874495 1.2463902746715114 0.9129842443793994 0.9423466380782478 1.1466611858205225 1.0822379384559044 0.8347703436758052 1.0 14.181321602450312 -5.260693431004148 24.999836619790404 1.063978801477148 0.7821894296153976 0.27491684193507004 0.1809748499966108 81.84027953399968 2742679.0713399304 0.04660950276785935 0.10939675487155667 5.4866413092262255e-06 5.260693431004148 -0.28178937186175046 ES(ph)NRLSAPSYLAR ddPTM_PC-9_Lapatinib_30min_R1 1 ESNRLSAPSYLAR 13 1 H0YJH0;Q9H4B6 H0YJH0 SAV1 Protein salvador homolog 1 1 ES(0.747)NRLS(0.253)APSYLAR 77.372 0.0076402 18204000.0 38152.0 37306.0 31983.0 29146.0 43698.0 42503.0 27333.0 24579.0 39046.0 25017.0 True False 37607.94548378007 37219.62024907379 29353.48119795024 31289.494068205768 41127.769553573504 40685.245769332236 28748.168998603847 25721.030070050965 34648.228307391895 29341.155116942864 1.2817472704768738 1.268512439293215 1.0004200952879412 1.0664029396081223 1.4017092847794712 1.3866272683258745 0.9797899531911544 0.8766195457382835 1.180874719120533 1.0 14.84063804840265 -7.2875269757093175 24.63050659582842 0.9990393018853275 1.2251501272062109 0.392543062252773 0.13654961836121993 737.9536933306789 696732.7001240893 0.061916038391302365 0.041760963680771354 5.15790126358423e-08 7.2875269757093175 0.22611082532088334 ES(ph)PEGSYTDDANQEVR ddPTM_PC-9_AZD4547_30min_R2 1 ESPEGSYTDDANQEVR 16 0 A0A075B6Q2;S4R347;Q5T0N5-3;Q5T0N5-4;Q5T0N5-2;Q5T0N5-5;Q5T0N5 A0A075B6Q2 FNBP1L Formin-binding protein 1-like 1 ES(1)PEGSYTDDANQEVR 239.7 2.2616999999999996e-37 12787000.0 9048.9 9243.4 10850.0 9587.3 9377.7 12249.0 11100.0 13067.0 14282.0 10329.0 True False 11926.261971187492 12231.14828546114 10706.12191073594 7377.096107308436 8075.768225884792 11483.068093641601 12087.878496450712 11047.795399788212 15036.917362719129 9967.38485390292 1.1965286929316807 1.2271170888592509 1.0741154342549293 0.7401235344514457 0.810219364884117 1.1520642838572834 1.212743229405602 1.1083945851114836 1.5086120966655698 1.0 13.282999318552838 -8.023162093774006 21.32720579877674 1.272372071044099 1.0558394841144572 0.13577361895451312 0.19322090415282123 229.3487151085969 211172.46584546156 0.13661695891202816 0.052768566901500565 9.480645466640698e-09 8.023162093774006 -0.21653258692964195 ES(ph)PEGSYTDDANQEVR ddPTM_PC-9_Lapatinib_30min_R1 2 ESPEGSYTDDANQEVR 16 0 A0A075B6Q2;S4R347;Q5T0N5-3;Q5T0N5-4;Q5T0N5-2;Q5T0N5-5;Q5T0N5 A0A075B6Q2 FNBP1L Formin-binding protein 1-like 1 ES(1)PEGSYTDDANQEVR;ES(1)PEGSYTDDANQEVR 244.18 7.1414e-47 22550000.0 26513.0 32678.0 25335.0 20920.8 28747.0 27717.0 30163.0 31714.0 28240.0 24406.0 True False 26134.91975811127 32602.33609873032 23252.054095928124 22459.385421742936 27056.157978776544 26531.60852148273 31724.692551307522 33187.54821764908 25059.313819616535 28624.544581049184 0.9130248232984582 1.1389643599889665 0.8123117567893847 0.7846198341479333 0.945208329941047 0.9268831665202429 1.1083038355939743 1.1594087767468209 0.8754484721551516 1.0 14.804965119540217 -7.2130646327329435 10.318878621749818 1.0490347505594544 0.9201050506738672 0.19835584207274826 0.1126199407226821 1.11737123787668 235.35235159949104 0.04472542942171801 0.034589744713608275 6.122592670706632e-08 7.2130646327329435 -0.12892969988558722 ES(ph)PGAAATSSSGPQAQQHR ddPTM_PC-9_AZD4547_30min_R2 3 ESPGAAATSSSGPQAQQHR 19 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 ES(1)PGAAATSSSGPQAQQHR;ES(1)PGAAATSSSGPQAQQHR;ES(1)PGAAATSSSGPQAQQHR 301.7 2.4886999999999996e-122 10959700.0 12662.400000000001 17821.5 29298.699999999997 24583.899999999998 25222.4 32755.3 23106.100000000002 36979.1 27194.5 20301.2 True False 16688.779805718324 23581.95135657287 28910.180094569492 18916.461672468784 21720.70513031518 30707.105912944662 25162.498137553153 31264.82979018199 28631.94575132791 19590.46116720435 0.8518829476896838 1.2037466170551678 1.4757273883356523 0.9655955268748914 1.1087388369742408 1.5674519170763712 1.2844260236036067 1.5959210721655321 1.4615248465543815 1.0 14.257863739166572 -6.744211114158217 24.914648976416164 1.4130199219814041 1.1367856760934925 0.2555360936609957 0.21849582117308633 313.5359720561859 453418.95697467873 0.0709141006544503 0.0707451346868928 1.8021414919393112e-07 6.744211114158217 -0.2762342458879117 ES(ph)PGAAATSSSGPQAQQHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ESPGAAATSSSGPQAQQHR 19 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 ES(1)PGAAATSSSGPQAQQHR;ES(1)PGAAATSSSGPQAQQHR;ES(1)PGAAATSSSGPQAQQHR;ES(1)PGAAATSSSGPQAQQHR 218.64 5.735399999999999e-28 13432300.0 24852.600000000002 46583.5 61575.4 41272.2 48299.3 38796.2 47658.6 34354.1 38142.5 26998.199999999997 True False 29059.65431877533 51208.00202037366 63043.59106200493 38959.852440277784 38835.398884426104 36761.65897519322 43144.03238961602 33452.34127617775 38700.26190397944 31892.759942366392 0.9111677500250595 1.6056309367051318 1.9767367633259525 1.221589241905761 1.2176869908595493 1.1526647126691276 1.3527845337807662 1.048900795560801 1.2134497601936904 1.0 14.96094133078883 -5.965741221011096 24.999554438294638 1.179549000324813 1.5237138423792804 0.24874411102393068 0.2588043222747562 247.18261820497875 180374.34606922758 0.07329056817848748 0.10870688083736782 1.082078527246336e-06 5.965741221011096 0.3441648420544674 ES(ph)PGAAATSSSGPQAQQHR ddPTM_PC-9_Lapatinib_30min_R1 2 ESPGAAATSSSGPQAQQHR 19 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 ES(1)PGAAATSSSGPQAQQHR;ES(1)PGAAATSSSGPQAQQHR 245.67 1.0824000000000001e-53 10797600.0 7439.1 14182.6 15402.1 11807.4 13746.1 17603.5 15402.0 18093.8 12946.2 11589.7 True False 7333.017069836137 14149.76106107635 14135.798791825327 12675.755584331737 12937.581423872418 16850.63934076276 16199.440197435204 18934.504002664395 11488.06262647025 13592.964202695473 0.5394715207432096 1.0409621367405988 1.0399349679021601 0.9325232815531247 0.9517851464147096 1.239658921298512 1.1917518471962774 1.3929635744137174 0.845147714300033 1.0 13.730572476877397 -6.668743130659674 5.82190619589213 1.1614417373741652 0.9144119491633373 0.2681547858310138 0.1897173535859484 0.27945773258064643 14.231582017829501 0.06206096186045729 0.06172058507640282 2.1441584176215017e-07 6.668743130659674 -0.24702978821082788 ES(ph)PRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGR ddPTM_PC-9_Lapatinib_30min_R1 1 ESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGR 40 1 Q6PKG0;A0A0B4J210 Q6PKG0 LARP1 La-related protein 1 1 ES(0.799)PRPLQLPGAEGPAIS(0.201)DGEEGGGEPGAGGGAAGAAGAGR 110.13 1.0081e-26 9113400.0 3209.0 9585.5 6566.1 7721.7 6485.0 9400.4 11538.0 8791.6 10336.0 6214.2 True False 3163.239071541471 9563.305363681366 6026.260603878974 8289.579576836082 6103.565050000549 8998.366805402688 12135.381184132419 9200.089831313733 9171.850837094775 7288.316190098987 0.4340150713876354 1.3121419425618361 0.8268385243858537 1.137379246539453 0.8374451506772036 1.2346290378601803 1.6650459266048392 1.2623066276696182 1.2584320709843142 1.0 12.831369833812024 -6.885902199012594 5.408841446628115 1.335176682198503 0.9415849866290744 0.3303751815613196 0.26290872523779174 0.23729345748967684 10.328840384031503 0.08898242216174929 0.0784300778875574 1.3004624028159332e-07 6.885902199012594 -0.3935916955694285 ES(ph)PSLASR ddPTM_PC-9_AZD4547_30min_R2 2 ESPSLASR 8 0 H3BUF6;Q8WWM7-7;H3BSK9;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 ES(1)PSLASR;ES(0.994)PS(0.006)LASR 154.01 5.0338000000000005e-05 34883000.0 118458.0 137611.0 157327.0 201747.0 225368.0 182555.0 166358.0 244721.0 171296.0 140210.0 True False 156125.17992053516 182091.06462022566 155240.7411843645 155237.34611007848 194079.5433348476 171139.80699116248 181163.53972185106 206904.99257913578 180350.35685228487 135301.29057660242 1.1539075440832034 1.3458191259242474 1.1473707347711746 1.14734564207419 1.434424923130849 1.2648793390057846 1.338963870557341 1.5292166962885996 1.3329537071206086 1.0 17.045816075019438 -6.252386630326582 24.897358371832397 1.3417187768431436 1.2054656440484233 0.13126861643689136 0.13986444885022659 1084.8837483504992 2983704.435173315 0.039968195451463406 0.05085013637412103 5.592594994737263e-07 6.252386630326582 -0.1362531327947203 ES(ph)PSLASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESPSLASR 8 0 H3BUF6;Q8WWM7-7;H3BSK9;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 ES(0.989)PS(0.005)LAS(0.006)R;ES(0.994)PS(0.006)LASR 114.97 0.0036543 34658000.0 141128.0 306270.0 261220.0 219791.0 244080.0 168204.0 193371.0 151565.0 125914.0 142134.0 True False 165018.18299494332 336674.4615320838 267448.4754823662 207476.82284203602 196254.27614294091 159383.0861337812 175053.4989951959 147586.57934639193 127755.25404411495 167901.76906787526 0.9828257552678541 2.00518710077427 1.5928865846210867 1.2357036140468676 1.1688636589862493 0.9492638881568286 1.0425947264702704 0.8790055052173346 0.7608928408161629 1.0 17.357257905497967 -6.237210166267209 1.4382755986204454 0.9204891212257024 1.5678248810815822 0.5122564672916292 0.24799510654631896 0.31096620304248584 1.290781691528612 0.09148401281561105 0.12964278553795153 5.791483638168436e-07 6.237210166267209 0.6473357598558799 ES(ph)PSLASR ddPTM_PC-9_Lapatinib_30min_R1 2 ESPSLASR 8 0 H3BUF6;Q8WWM7-7;H3BSK9;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 ES(1)PSLASR;ES(0.996)PS(0.004)LASR 166.78 0.00040835 35171000.0 191160.0 246470.0 220750.0 208867.0 248960.0 243420.0 233500.0 227280.0 213180.0 186698.0 True False 188434.02334554962 245899.31385807163 202600.7871196422 224227.77593988713 234316.66227419238 233009.49403973448 245589.48747572556 237840.2585264327 189169.42351507978 218968.5005405524 0.8605531064074311 1.1229894402666913 0.9252508311446425 1.0240184108049857 1.070093011989172 1.0641233486301456 1.1215745044125331 1.0861848071265634 0.8639115811091107 1.0 17.74036382196904 -5.9879197902744545 24.40430089052854 1.0447116350294834 0.9832198821350044 0.08226307774774522 0.09015532238311115 442.12601973480923 893166.3333013757 0.024750170813968696 0.03668018630644909 1.0282061797010854e-06 5.9879197902744545 -0.061491752894478946 ES(ph)PSPAPKPR ddPTM_PC-9_AZD4547_30min_R2 2 ESPSPAPKPR 10 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 ES(0.999)PS(0.001)PAPKPR;ES(0.897)PS(0.103)PAPKPR 74.237 0.01234 12346900.0 57245.0 51868.0 72431.0 90695.0 80064.0 64968.0 72020.0 75948.0 66196.0 73605.0 True False 75447.71923003111 68633.31666597765 71470.51761442526 69786.66897378191 68948.49560523793 60905.54068966511 78429.64047877284 64211.98171141921 69694.98541818757 71028.1113536185 1.062223361880049 0.9662838467474069 1.0062286079747245 0.9825218162755873 0.9707212298236813 0.8574850088078866 1.1042056304764363 0.9040361694503645 0.9812310096661043 1.0 16.116102503938514 -2.455008890258721 1.448383836799506 0.9715108780965293 89.22453226152926 0.14678026317074322 0.06142155728516788 2484.1672725105514 7.047269156574169 0.016294184015675933 727596.2945213587 0.0035074469393274283 2.455008890258721 88.25302138343274 ES(ph)PSPAPKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESPSPAPKPR 10 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 ES(0.989)PS(0.011)PAPKPR;ES(0.997)PS(0.003)PAPKPR 94.402 0.0029802 10790800.0 68601.0 75053.0 72814.0 80950.0 91589.0 74457.0 85025.0 72284.0 69292.0 63026.0 True False 80213.79436848899 82503.76583200293 74550.16190863258 76414.63394344087 73642.79292713759 70552.34384594265 76970.81647230721 70386.62159122861 70305.26441241498 74452.11488645847 1.0773877208299218 1.1081453623959971 1.0013169138623348 1.026359480317991 0.9891296310312324 0.9476204128457187 1.0338298192024475 0.9453945223526579 0.9443017773186491 1.0 16.18402521012808 -5.4451678051169194 0.9553380652132868 0.9737950849941149 1.11194553978312 0.6422430623523021 0.03161099464179322 0.5495978977530204 0.7640190780902756 0.011769509191468044 0.06356010121122671 3.5878327918098273e-06 5.4451678051169194 0.138150454789005 ES(ph)PT(ph)ADSVY(ph)KYNIFRS(ph)TFHS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESPTADSVYKYNIFRSTFHSK 21 2 F8W889;Q2M3W8-2;Q2M3W8-3;Q2M3W8 F8W889 ZNF181 Zinc finger protein 181 5 ES(0.893)PT(0.893)ADS(0.3)VY(0.736)KY(0.178)NIFRS(0.647)T(0.647)FHS(0.706)K 45.257 0.044926 0.0 8565.5 17239.0 15687.0 11053.0 12115.0 7704.0 13604.0 9955.6 11665.0 9241.5 True False 10015.46997366353 18950.37399141803 16061.037573278792 10433.73624430949 9741.152718255185 7299.9886778831 12315.330635569166 9694.276048830126 11835.57855698814 10916.910794326246 0.9174271149003788 1.7358733022960073 1.4712071826790103 0.9557407256393564 0.8922993786225561 0.6686862992117752 1.1280966628370461 0.8880054285932657 1.0841508902994192 1.0 13.414277047874634 -5.767695263038796 23.98570226525052 0.9345009547035151 1.4109396528877467 0.4375671498551065 0.22180725686278271 70.97138639005152 272113.95873652486 0.060348912266238265 0.09219134812621146 1.7072799377443657e-06 5.767695263038796 0.47643869818423157 ES(ph)PTQISIGAFPSTK ddPTM_PC-9_AZD4547_30min_R2 1 ESPTQISIGAFPSTK 15 0 A0A2R8YH03;Q5VWN6;Q5VWN6-2 A0A2R8YH03 FAM208B Protein FAM208B 1 ES(0.857)PT(0.143)QISIGAFPSTK 177.44 4.5518e-05 8078600.0 18748.0 23361.0 20215.0 16609.0 16888.0 24462.0 19734.0 25969.0 18875.0 21602.0 True False 24709.474017374854 30911.98640074625 19946.93589175365 12780.051656492018 14543.39270809926 22932.387272974192 21490.287770176437 21956.087758253623 19872.693965923776 20845.72055513708 1.185349959576505 1.4828936384800815 0.9568839723718766 0.6130779515483138 0.6976680258968205 1.1001004840450521 1.0309208412026092 1.0532659545243166 0.9533224775493061 1.0 14.347463620890105 -5.3268000778448865 7.184953603310932 0.9169549244616585 1.3328894341554236 0.5072245685281083 0.16099156678236057 0.20308875177993166 19.41900057129814 0.0464564967310388 0.09790441300119786 4.7119418496131394e-06 5.3268000778448865 0.4159345096937651 ES(ph)PTQISIGAFPSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESPTQISIGAFPSTK 15 0 A0A2R8YH03;Q5VWN6;Q5VWN6-2 A0A2R8YH03 FAM208B Protein FAM208B 1 ES(0.714)PT(0.201)QIS(0.084)IGAFPS(0.001)TK 83.751 0.006450399999999999 7081900.0 32370.0 44927.0 42257.0 35289.0 39615.0 30416.0 41220.0 27813.0 28702.0 29964.0 True False 37849.601663357476 49387.055647800786 43264.56714056491 33311.87173848163 31852.72512865696 28820.93141569217 37315.34319304332 27082.938220309414 29121.712451150743 35396.23600510651 1.0693114843594393 1.3952629211952328 1.2222928769692705 0.9411133922170657 0.8998901782681542 0.8142371807989487 1.0542178323045406 0.7651361070256802 0.8227347237415141 1.0 15.111308333488166 -5.785382186273583 3.9237871828831565 0.8881353989442152 1.2517320008547157 0.6576747802097267 0.10913800771241389 0.11748611697110183 3.9233181109409734 0.030181496758978816 0.04958812123458611 1.6391466623404683e-06 5.785382186273583 0.36359660191050047 ES(ph)PVSAPLEGLICR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESPVSAPLEGLICR 14 0 O75376-2;O75376;A0A088AWL3 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 ES(0.999)PVS(0.001)APLEGLICR 101.43 0.0017112000000000002 1863100.0 4041.0 4822.8 4042.7 5339.9 4649.6 4579.9 6697.8 1961.1 4678.4 1141.0 True False 4725.061486611912 5301.575711225182 4139.093300025127 5040.722715189384 3738.544257432878 4339.721981546833 6063.335896127252 1909.6232029572056 4746.81274933676 1347.854267848969 3.50561748352261 3.933344900621882 3.0708759832253056 3.7398128532351183 2.773700648957542 3.219726408903661 4.49850999530067 1.4167875923298145 3.521755179743701 1.0 10.396448803127479 -10.136149417737538 0.29303458756475337 2.7054925010126907e-12 3.652746402128758 0.4733901438230752 0.7526337517484707 8.762068174487807 0.7874893498520917 9.086366547890753 0.879235063889096 7.308875805017985e-11 10.136149417737538 3.6527464021260525 ES(ph)RSPQQSAALPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESRSPQQSAALPR 13 1 E5RJN3;A0A0A6YYG7;Q6IBW4-2;Q6IBW4;Q6IBW4-4 E5RJN3 NCAPH2 Condensin-2 complex subunit H2 1 ES(0.95)RS(0.05)PQQSAALPR;ES(0.964)RS(0.036)PQQSAALPR 80.87100000000001 0.0057896 34367000.0 115636.0 101515.0 110605.0 131668.0 137606.0 103716.0 130565.0 111618.0 123622.0 81740.0 True False 135210.89088489334 111592.7383107376 113242.2426717981 124291.06883341545 110643.09211293644 98276.95037841688 118196.93799125914 108688.14576904682 125429.73788015345 96558.81494651611 1.4002956742974382 1.1556970575141043 1.1727799552482385 1.2872058227129262 1.1458621584598114 1.0177936673399777 1.2240926740528908 1.1256159867874223 1.298998314650288 1.0 16.55912034974682 -4.760167008890059 24.88376061582782 1.164296460643024 1.4002959743183214 0.37455225727721886 0.09341584965113793 32.74881646849768 640201.5482146073 0.022403981084774652 0.13490404788604346 1.7371326821280014e-05 4.760167008890059 0.23599951367529748 ES(ph)S(ph)PLYSPTFSDSTSAVK ddPTM_PC-9_AZD4547_30min_R2 1 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 ES(0.941)S(0.938)PLY(0.03)S(0.077)PT(0.009)FS(0.005)DSTSAVK 92.925 0.019215 0.0 11625.0 10233.0 19541.0 24592.0 27971.0 20083.0 16314.0 23745.0 18901.0 20866.0 True False 15321.508184978797 13540.617132778407 19281.873572137425 18922.694342612533 24087.70946460472 18827.206835219575 17765.91439559432 20075.755855817795 19900.06827284374 20135.48769111611 0.7609206402156691 0.6724752506865082 0.957606484030913 0.9397683648338614 1.1962814029695614 0.9350261152863083 0.8823185545901994 0.9970335044169468 0.988308233608057 1.0 14.297452795018316 -5.322417342419362 5.08490181680008 0.9891372127156093 0.7165775943706268 0.6455116940403143 0.08025038951363957 0.12111748431324988 6.455594266749287 0.022068600367101107 0.04863157047517681 4.7597337253041236e-06 5.322417342419362 -0.27255961834498244 ES(ph)SPIPS(ph)PTSDRK ddPTM_PC-9_AZD4547_30min_R2 1 ESSPIPSPTSDRK 13 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 2 ES(0.829)S(0.171)PIPS(0.975)PT(0.021)S(0.005)DRK 84.62 0.0064118 10302000.0 72890.0 83475.0 91825.0 81445.0 103070.0 97950.0 99210.0 101110.0 93218.0 95826.0 True False 96067.50379381534 110456.66130740529 90607.34050261088 62669.11356270652 88760.50961770419 91825.17101577221 108039.49780476354 85485.77277665763 98145.3131716811 92471.16090716417 1.0388915079184708 1.1944984817298612 0.9798443062002383 0.6777152243781472 0.9598723401646783 0.9930141474914488 1.168358834742316 0.9244587386815715 1.0613613175053946 1.0 16.496715880276746 -9.5515472021936 15.742927906775112 0.9999999999908874 0.996817846171313 0.0 0.13534026023629608 0.0 0.0 0.14029487445626898 0.03402650506564507 2.808360123754023e-10 9.5515472021936 -0.0031821538195744292 ES(ph)SPIPS(ph)PTSDRK ddPTM_PC-9_Lapatinib_30min_R1 2 ESSPIPSPTSDRK 13 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 2 ES(0.5)S(0.5)PIPS(0.519)PT(0.26)S(0.221)DRK;ES(0.796)S(0.218)PIPS(0.957)PT(0.015)S(0.013)DRK 68.944 0.023885 25230000.0 160825.0 176793.0 173711.0 159926.0 191123.0 180975.0 169199.0 171040.0 190189.0 152696.0 True False 158531.60600830716 176383.64667062994 159429.15212385167 171687.49153749688 179881.52090227514 173235.12112333023 177959.29632293485 178987.1428122181 168767.91204104293 179089.30014536923 0.8852098136495307 0.984892154514295 0.8902215374924178 0.9586697329105414 1.0044236074196664 0.9673113970667869 0.9936902773001115 0.9994295732181198 0.9423673659121551 1.0 17.45031961919596 -5.995497562426814 24.35034699608791 0.9838723320202868 0.9262294778836234 0.46503461322698203 0.030721812171441584 83.94434246963745 453980.3682613931 0.008071826641161938 0.011914861497402292 1.010421171723095e-06 5.995497562426814 -0.05764285413666337 ES(ph)SPIPSPTSDRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESSPIPSPTSDRK 13 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 ES(0.499)S(0.499)PIPS(0.002)PTSDRK;ES(0.5)S(0.5)PIPSPTSDRK 107.11 0.0004789 16073300.0 73280.0 78294.0 73975.0 74780.0 86787.0 68607.0 73472.0 49041.0 58519.0 50744.0 True False 85684.85665402656 86066.51089298022 75738.8445517499 70590.31904003103 69781.7103556923 65009.12814427906 66512.20026878393 47753.72571323462 59374.72966792875 59943.48551071699 1.4294273334957708 1.4357942345143213 1.2635041807538692 1.1776145220552872 1.1641250047633012 1.0845069750349503 1.1095817952877056 0.7966457957253249 0.9905117989395769 1.0 15.871315353671667 -5.836275371877099 0.4896750263299188 0.9266507779123948 1.5654700333684233 0.8387244237863875 0.075354702713115 0.6858908066529478 0.2580713875037539 0.05997152186842874 0.22838389850650312 1.4578895672220404e-06 5.836275371877099 0.6388192554560285 ES(ph)SPIPSPTSDRK ddPTM_PC-9_Lapatinib_30min_R1 1 ESSPIPSPTSDRK 13 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 ES(0.499)S(0.499)PIPS(0.001)PTSDRK 60.08 0.026976999999999998 6158800.0 22133.0 22642.0 27162.0 21369.0 17646.0 22258.0 20204.0 16706.0 23255.0 19428.0 True False 21817.37936130491 22589.573840120345 24928.8452083521 22940.547544894296 16608.09697337082 21306.077225932197 21250.064261068754 17482.22174825141 20635.777013993724 22786.103913817245 0.9574861698087441 0.991375003184387 1.094037194890326 1.0067779744909966 0.7288695354057368 0.9350469613636943 0.9325887541565606 0.7672317222098851 0.9056299002253041 1.0 14.475866645761716 -6.042994415890075 24.766073499972553 0.8717552046298516 1.0184071331869788 0.39137286939557714 0.08173387833274864 394.35797579495784 227161.29531880692 0.023531831846110768 0.030382064472769275 9.057442467816573e-07 6.042994415890075 0.14665192855712728 ES(ph)SPLSSR ddPTM_PC-9_AZD4547_30min_R2 1 ESSPLSSR 8 0 Q14693;Q14693-2;Q14693-4;Q14693-3;Q14693-5;Q14693-7;A0A0A0MS66;Q14693-6 Q14693 LPIN1 Phosphatidate phosphatase LPIN1 1 ES(0.5)S(0.5)PLSSR 126.31 0.003513 4551000.0 23423.0 28453.0 36130.0 42654.0 35909.0 38710.0 27515.0 43395.0 32798.0 31816.0 True False 30871.026771334076 37649.87582125905 35650.892593077384 32820.77929773076 30923.65518445856 36289.45758060794 29963.781696382095 36689.299867896945 34531.63532155593 30702.131524036693 1.0055010919083958 1.2262951773163686 1.161186237677547 1.069006536957715 1.0072152534506744 1.181984956067201 0.9759511867416585 1.195008230590534 1.1247308772200757 1.0 14.906051199066976 -11.89222884641518 2.19719017351191 0.3028188371390393 1.1075672406445365 0.12442893445168401 0.08351501009945984 3035627.211051891 752205.0418462117 10314415.481214255 0.02022799587126896 1.28165505149937e-12 11.89222884641518 0.8047484035054973 ES(ph)SPLSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESSPLSSR 8 0 Q14693;Q14693-2;Q14693-4;Q14693-3;Q14693-5;Q14693-7;A0A0A0MS66;Q14693-6 Q14693 LPIN1 Phosphatidate phosphatase LPIN1 1 ES(0.5)S(0.5)PLS(0.001)SR 91.265 0.0088545 5000000.0 24687.0 28637.0 27748.0 31947.0 26602.0 25923.0 27764.0 26581.0 22173.0 22666.0 True False 28866.021509524442 31479.892104660263 28409.617554875993 30157.11316357146 21389.52906405484 24563.55224516664 25133.992926046918 25883.27691489752 22497.23817780523 26775.166376042733 1.0780893423449467 1.1757122873689074 1.0610435489318077 1.12630908581598 0.7988569991928518 0.9174005457215403 0.9387053874121108 0.9666896762238895 0.8402277641096113 1.0 14.708607919198968 -6.24309249787739 24.823366667279352 0.9104218363263444 1.1114442101638886 0.7194867824091609 0.0611694648212187 392.5361193457444 531101.9939866572 0.017520489392421013 0.022573939467174703 5.71356933693278e-07 6.24309249787739 0.20102237383754418 ES(ph)SPLY(ph)SPTFSDSTSAVK ddPTM_PC-9_Lapatinib_30min_R1 1 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 ES(0.318)S(0.682)PLY(0.538)S(0.25)PT(0.089)FS(0.122)DS(0.001)T(0.001)SAVK 134.85 5.3333e-06 0.0 10448.0 12141.0 11131.0 7751.2 9125.1 10563.0 10174.0 11762.0 10244.0 11394.0 True False 10299.009604071463 12112.88826044082 10215.852146902547 8321.249105245199 8588.379558636858 10111.245113555664 10700.759938235675 12308.50545929206 9090.212845897726 13363.43771844933 0.7706856439980881 0.9064200780999622 0.7644628846362429 0.6226877604822468 0.6426774112756848 0.7566350310890628 0.8007490410541886 0.9210583173743648 0.6802301202293132 1.0 13.706003565608647 -10.44422829904926 6.464296880250003 1.0000000250189511 0.7650443937861481 0.3646009838590305 0.09388167020045331 3.6707755829305016e-08 6.13530494265145e-09 0.09857652966500544 0.02390831774238605 3.595602725465868e-11 10.44422829904926 -0.23495563123280305 ES(ph)SPLYS(ph)PTFSDSTSAVK ddPTM_PC-9_AZD4547_30min_R2 1 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 ES(0.498)S(0.502)PLYS(0.898)PT(0.089)FS(0.012)DSTSAVK 128.26 4.3886000000000006e-05 0.0 4967.0 3904.3 4576.4 6857.0 7870.5 6683.6 4770.1 7052.4 5019.9 4733.5 True False 6546.402679981907 5166.288622252194 4515.7139458333595 5276.224589593939 6777.816929719043 6265.6734354366135 5194.629659091851 5962.6136280298715 5285.2416656710375 4567.781605765268 1.4331689307823525 1.1310279405065065 0.9886011056513317 1.155095633936286 1.483831214952212 1.3717103785190463 1.1372324921435388 1.3053631155447762 1.157069694181574 1.0 12.157277959046844 -8.573360376050392 5.192661046557838 1.0000319035139613 1.2425134009707375 0.21923475365776524 0.14521852870544566 0.5248293351231175 46.486108924745466 0.15019561308839677 0.03903093143967085 2.6707892772546286e-09 8.573360376050392 0.24248149745677616 ES(ph)SPLYS(ph)PTFSDSTSAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 ES(0.498)S(0.498)PLY(0.006)S(0.554)PT(0.222)FS(0.222)DSTSAVK;ES(0.5)S(0.5)PLY(0.001)S(0.599)PT(0.354)FS(0.043)DS(0.003)TSAVK 139.88 0.00054524 4255700.0 17840.5 17820.5 18975.2 20964.7 26392.8 24838.9 25908.4 25307.2 19245.2 17699.6 True False 20860.544284063286 19589.601468418423 19427.640731846725 19790.115827474463 21221.320302300064 23536.304357615616 23454.168791427528 24642.91281519485 19526.624641658655 20908.39737004348 0.9977112982342322 0.9369250603819802 0.9291788551752747 0.9465151956519041 1.014966375792385 1.1256866770351932 1.1217583240039002 1.1786131848872357 0.93391302528215 1.0 14.351794863050355 -6.508599046952688 3.693193478319533 1.085976717957412 0.9509984654048035 0.40330932795933194 0.06713891718360594 0.20502541508170208 6.064375594859356 0.02202084564618577 0.023616453314369668 3.1002802454705693e-07 6.508599046952688 -0.13497825255260854 ES(ph)SPLYS(ph)PTFSDSTSAVK ddPTM_PC-9_Lapatinib_30min_R1 1 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 ES(0.685)S(0.315)PLYS(0.867)PT(0.064)FS(0.01)DS(0.026)T(0.026)S(0.006)AVK 137.52 9.223900000000001e-08 0.0 9930.5 10805.0 11725.0 10263.0 13092.0 13598.0 12996.0 11358.0 13463.0 10601.0 True False 9788.889248969333 10779.981686357223 10761.015759808857 11017.775256364366 12321.954299862326 13016.445238486205 13668.86929008362 11885.734144417553 11946.655168324984 12433.368725055407 0.7873078861759335 0.8670201877495742 0.86549478244971 0.8861456215129877 0.9910390797814463 1.0468961008335413 1.099369735777116 0.9559544486496026 0.9608542489575163 1.0 13.601929615962097 -6.171976064518299 2.1580348237179394 1.0163984559411567 0.8415996940306413 0.7643058428632437 0.04354523582283782 0.16542330391799132 1.5125755408642518 0.015666647991865883 0.021532980600799636 6.730137473941651e-07 6.171976064518299 -0.17479876191051547 ES(ph)SPLYSPTFSDSTSAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ES(0.629)S(0.371)PLYSPTFSDSTSAVK;ES(0.518)S(0.481)PLYSPTFS(0.001)DSTSAVK;ES(0.841)S(0.159)PLYSPTFSDSTSAVK 224.06 8.1168e-35 1294860900.0 163757.0 152112.0 173936.0 204131.0 209494.0 160462.0 167988.0 171944.0 155749.0 150386.0 True False 191477.82575182006 167212.6740868139 178083.29389595377 192694.2018716317 168445.15456526232 152047.09024279335 152074.96051220156 167430.6521897269 158026.53447684046 177649.79134507859 1.0778387314842435 0.9412489191276845 1.002440208612647 1.0846857765080617 0.9481866164315579 0.8558810516554287 0.856037934864788 0.942475929310261 0.8895396570991709 1.0 17.43867646861905 -6.502494063371292 8.934277379949728 0.9018496445813278 1.0185549043301056 0.5058194384063995 0.05456372220029997 0.22893274308820083 92.5713692810369 0.01700107055694192 0.01857917541154513 3.14416939948032e-07 6.502494063371292 0.11670525974877788 ES(ph)SPLYSPTFSDSTSAVK ddPTM_PC-9_Lapatinib_30min_R1 2 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ES(0.877)S(0.118)PLY(0.003)S(0.002)PTFSDSTSAVK;ES(0.32)S(0.32)PLY(0.32)S(0.04)PT(0.001)FSDSTSAVK 109.38 0.00016816 35746000.0 336872.0 333643.0 379986.0 351196.0 297350.0 295114.0 247956.0 224777.0 305388.0 228033.0 True False 332068.14350524085 332870.4701324648 348745.017868377 377024.1253955117 279860.45761259244 282492.6621643345 260793.94842197435 235220.96000878158 270991.9875617936 267448.20021512645 1.2416166690900752 1.244616601886701 1.3039721994309854 1.4097089645480732 1.0464099492443097 1.0562518720900227 0.9751194743961648 0.8795010017625008 1.013250369020306 1.0 18.028899969579285 -6.407115472666715 4.602543238886365 0.9832392980375303 1.295244340957106 0.8592591980641283 0.0607373148958664 0.08815801159083587 2.9493709272080233 0.021096518082619094 0.023882393046920712 3.916377324135746e-07 6.407115472666715 0.31200504291957565 ES(ph)SPLYSPTFSDSTSAVKEK ddPTM_PC-9_AZD4547_30min_R2 1 ESSPLYSPTFSDSTSAVKEK 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ES(0.563)S(0.431)PLY(0.004)SPT(0.001)FSDSTSAVKEK 114.87 0.00018647 0.0 17734.0 4045.0 4900.5 46447.0 23567.0 6974.5 3976.0 17537.0 1627.9 11578.0 True False 23373.04310988507 5352.467145713731 4835.51616807018 35739.36174899659 20295.128846031213 6538.383412450276 4329.856297467392 14827.05961016957 1713.9474705762832 11172.65774406893 2.0919859576198676 0.47906838894757325 0.4327990956885027 3.1988236431899146 1.8164996468100885 0.5852128976134809 0.3875404041411652 1.3270843831263515 0.1534055289115199 1.0 13.447684793490644 -6.767274385320001 24.90231026000669 0.6921470228585827 1.5649012062689875 0.246080423063332 0.7977401079961232 228.45084197158198 974962.9263276685 0.29392249127505843 0.26613971825237 1.7089352762457277e-07 6.767274385320001 0.8727541834104049 ES(ph)SPSHGLLK ddPTM_PC-9_AZD4547_30min_R2 2 ESSPSHGLLK 10 0 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 ES(0.609)S(0.269)PS(0.122)HGLLK;ES(0.499)S(0.499)PS(0.001)HGLLK 79.283 0.010902 12453200.0 52389.0 59354.0 136132.0 185909.0 157766.0 142778.0 100451.0 161579.0 118940.0 127451.0 True False 69047.61224110583 78539.01976926901 134326.80073293127 143050.55231541765 135862.9141393883 133850.06908922864 109390.94440062775 136610.67826604264 125226.92557917736 122988.97928306508 0.5614130033731674 0.6385858328696887 1.0921856699352845 1.163116834933477 1.1046755158988126 1.0883094556071258 0.8894369645011786 1.1107554437997778 1.0181963157118454 1.0 16.9081695197086 -5.2267926611540405 5.301124078107797 1.0632435735869499 0.58872367466774 0.8623408065866713 0.07332322072393725 0.06437990437569452 4.992044254720406 0.019774128578389887 0.05260874986636197 5.93208463805127e-06 5.2267926611540405 -0.47451989891920987 ES(ph)SPSHGLLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ESSPSHGLLK 10 0 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 ES(0.435)S(0.435)PS(0.131)HGLLK;ES(0.499)S(0.499)PS(0.002)HGLLK;ES(0.499)S(0.499)PS(0.002)HGLLK 87.667 0.0059396 11075100.0 71488.0 81408.0 113105.0 123935.0 143880.0 124933.0 124972.0 105269.0 102489.0 93059.0 True False 83589.50644763993 89489.64823327109 115801.85215310135 116991.32375269105 115687.74685122215 118381.29354802304 113133.74744107247 102505.80029172513 103987.70773486132 109929.86004536109 0.7603894557233843 0.8140613314375583 1.0534158062724475 1.0642360838485208 1.0523778234911347 1.0768802352625082 1.0291448328451374 0.9324654852596691 0.9459459667459977 1.0 16.746223790552044 -5.191084463757709 4.698047544928849 1.0221222645471042 0.7760643728681061 0.7986614513638153 0.04676117159918468 0.09985258061420019 4.218965453357622 0.013801494489260824 0.039010769002074265 6.4404399644427466e-06 5.191084463757709 -0.24605789167899805 ES(ph)SPSHGLLK ddPTM_PC-9_Lapatinib_30min_R1 3 ESSPSHGLLK 10 0 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 ES(0.457)S(0.457)PS(0.086)HGLLK;ES(0.496)S(0.496)PS(0.009)HGLLK;ES(0.499)S(0.499)PS(0.001)HGLLK 92.24700000000001 0.0042815 17692500.0 169899.0 126757.0 200762.0 148024.0 175470.0 193408.0 148677.0 160984.0 201704.0 127498.0 True False 167476.2091043393 126463.50195442671 184256.1233237314 158910.17875358844 165149.19958729346 185136.39069606853 156374.76757785195 168463.9043409856 178985.97148271714 149535.85941959402 1.119973561889293 0.8457068588449622 1.232186875033855 1.062689440314716 1.104412013468213 1.2380735391139879 1.04573423515137 1.1265786346824005 1.1969434768184053 1.0 17.190131965571 -5.269560022607964 24.991837439508434 1.128476514640385 0.9828402059283139 0.2592065877570522 0.09660711469684852 658.0066053998248 2025064.5240588342 0.02342843147146346 0.050150947452746245 5.375761311162145e-06 5.269560022607964 -0.14563630871207112 ES(ph)SVGYR ddPTM_PC-9_AZD4547_30min_R2 1 ESSVGYR 7 0 E9PNR2;Q13671-2;Q13671 E9PNR2 RIN1 Ras and Rab interactor 1 1 ES(0.5)S(0.5)VGYR 77.318 0.02997 5300400.0 27783.0 25817.0 36035.0 59107.0 46854.0 36821.0 26944.0 53101.0 35888.0 38315.0 True False 36617.41607770031 34161.84037104857 35557.152355149265 45480.7943440468 40349.13085891062 34518.5770492267 29341.96380255566 44895.46058958857 37784.96641319588 36973.60351217834 0.9903664398207573 0.9239521476395008 0.9616902053768568 1.230088225754527 1.0912956008093841 0.9336005628409194 0.7935922121545719 1.2142571003337808 1.0219443825850052 1.0 15.174208037513358 -5.562567989269087 24.999923764536693 1.0414945225486525 0.9535733329273174 0.08848906568299153 0.12055142195905658 385.41107738617023 242765.4364969658 0.034709093731563535 0.06011801441452978 2.737990965275189e-06 5.562567989269087 -0.0879211896213351 ES(ph)SVGYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESSVGYR 7 0 E9PNR2;Q13671-2;Q13671 E9PNR2 RIN1 Ras and Rab interactor 1 1 ES(0.607)S(0.393)VGYR 71.692 0.040763 5661000.0 30678.0 34272.0 29542.0 27762.0 46463.0 23591.0 29494.0 29944.0 25487.0 25056.0 True False 35871.17948188077 37674.29766424266 30246.393318658895 26206.585145618395 37358.9086874363 22353.846430418 26700.114801931566 29158.00172829057 25859.69915833319 29598.45445681314 1.211927451624885 1.2728467872946851 1.0218909694352845 0.8854038370096725 1.2621911979203635 0.7552369487073832 0.9020780068394951 0.9851190632549672 0.8736841038799801 1.0 14.853234224129839 -5.364633105370714 3.9953930269750053 0.9539726515321278 1.2427649651841972 0.4578244559380652 0.12419400086513195 0.19469943776385462 5.423135300000584 0.03291227160529226 0.07476178343955638 4.318837808082855e-06 5.364633105370714 0.28879231365206937 ES(ph)TGNMVTGQTVCK ddPTM_PC-9_AZD4547_30min_R2 1 ESTGNMVTGQTVCK 14 0 Q15021;E7EN77 Q15021 NCAPD2 Condensin complex subunit 1 1 ES(0.607)T(0.366)GNMVTGQT(0.027)VCK 107.13 0.00071343 4986400.0 21521.0 30681.0 32770.0 40353.0 41853.0 49880.0 38701.0 50899.0 40603.0 43306.0 True False 28364.23033539174 40598.033250344415 32335.448388462377 31050.23929763513 36042.43338536703 46760.99571482108 42145.31402622876 43033.72909266245 42749.19168733262 41789.87012132052 0.6787345893406059 0.9714802446737434 0.7737628352179384 0.743008753257498 0.8624681838142101 1.1189552774169635 1.0085055039385467 1.0297646048607203 1.0229558398537033 1.0 15.35086565446682 -6.616481614141374 5.471443126322651 1.0351386664561775 0.8032203909484352 0.7010765237581649 0.07602142076184032 0.11854110478657358 5.565494575873628 0.024713989208437284 0.024692194376683026 2.4183457164388634e-07 6.616481614141374 -0.23191827550774224 ES(ph)TGNMVTGQTVCK ddPTM_PC-9_Lapatinib_30min_R1 1 ESTGNMVTGQTVCK 14 0 Q15021;E7EN77 Q15021 NCAPD2 Condensin complex subunit 1 1 ES(0.959)T(0.036)GNMVT(0.002)GQT(0.003)VCK 78.505 0.012215 6259500.0 37219.0 43344.0 53257.0 42396.0 40478.0 44241.0 35630.0 30472.0 41252.0 23949.0 True False 36688.25023487134 43243.6396310474 48878.415037965075 45513.943268910036 38097.16362280992 42348.91556080809 37474.747061071095 31887.840363505144 36605.765357182056 28088.55273996339 1.3061637804739084 1.5395467339092161 1.7401542717586376 1.6203733844981776 1.3563234807967388 1.507693043243042 1.3341643981447775 1.1352610673363837 1.3032271792736647 1.0 14.777694671202525 -7.7119386466502355 0.7120286930269678 1.0498014031628697 1.5551889779578822 0.6222643670127637 0.12999544646343852 0.455993386973547 0.4472433906653442 0.1245941523275954 0.06224627019419286 1.9411600884491034e-08 7.7119386466502355 0.5053875747950125 ES(ph)TQLSPADLTEGKPTDPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESTQLSPADLTEGKPTDPSK 20 1 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 ES(0.382)T(0.347)QLS(0.256)PADLT(0.015)EGKPTDPSK 56.72 0.009571399999999999 6158700.0 11485.0 17109.0 13375.0 9046.9 15394.0 12659.0 20170.0 9957.9 10115.0 10847.0 True False 13429.183660910117 18807.4684505581 13693.910724969961 8540.031523445534 12377.656206753632 11995.139755104126 18259.351581845793 9696.515676267187 10262.912739300044 12813.47523519525 1.0480516342688733 1.4677882545789704 1.0687116862220474 0.6664883153625888 0.9659874452135719 0.9361347749092009 1.4250116573911307 0.7567436232782037 0.8009468587499602 1.0 13.64537419204549 -5.5156498830153735 24.556383531725874 0.941269824328566 1.2605025054170853 0.26530735717063403 0.2134105924676365 329.2223645050949 1118362.9360607162 0.058267196788180715 0.10657777193867125 3.0503531144845583e-06 5.5156498830153735 0.3192326810885193 ES(ph)VLDPGVGGEGASDKQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESVLDPGVGGEGASDKQR 18 1 P0C7Q2 P0C7Q2 ARMS2 Age-related maculopathy susceptibility protein 2 1 ES(1)VLDPGVGGEGASDKQR 83.292 0.011033 8463500.0 29667.0 31205.0 35669.0 44370.0 56842.0 58399.0 67914.0 56722.0 67270.0 54692.0 True False 34689.037150040946 34302.8261733395 36519.48423543577 41884.09274948086 45704.21814371118 55336.453634436046 61480.69426521936 55233.10760192679 68253.69648766318 64607.22665836623 0.5369219349635856 0.5309441055987116 0.5652538597353137 0.6482880463350942 0.7074164997886158 0.856505634068574 0.9516070793491954 0.854906029227838 1.0564405874992742 1.0 15.97940792652858 -6.614015277428119 0.7518117656323392 0.9958585725373661 0.511540886319905 0.9448959554222021 0.04421263524712726 0.13952597559849872 0.1753933552613951 0.028476924745553654 0.03291035183117157 2.4321184515318383e-07 6.614015277428119 -0.4843176862174611 ES(ph)YSVYVYK ddPTM_PC-9_AZD4547_30min_R2 1 ESYSVYVYK 9 0 U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 U3KQK0 HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 1 ES(0.5)YS(0.5)VYVYK 139.15 0.00084761 14421000.0 20013.0 33785.0 34827.0 49709.0 29344.0 29260.0 18723.0 24962.0 21896.0 23361.0 True False 26376.71770374029 44705.34054831606 34365.171224442456 38249.3580463942 25270.092114309828 27430.367574492073 20389.31072874295 21104.69646969568 23053.377858430053 22543.138500535006 1.1700552566411417 1.983101889173732 1.5244182270195823 1.6967184070437418 1.120966014280137 1.2167945281372903 0.9044575017031927 0.9361915808304514 1.022633909554472 1.0 14.4604007639128 -6.454911262528274 1.8565373260455436 0.9883863704614835 1.6248262364794968 0.633384187313336 0.2069270653376178 0.20476387346212188 1.4096220884241 0.07251549794352058 0.08280558915908182 3.5082354885476304e-07 6.454911262528274 0.6364398660180133 ESAAPAAAPTAEAPPPS(ph)VVTRPEPQALPSPAIR ddPTM_PC-9_AZD4547_30min_R2 1 ESAAPAAAPTAEAPPPSVVTRPEPQALPSPAIR 33 1 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 1 ESAAPAAAPTAEAPPPS(0.395)VVT(0.395)RPEPQALPS(0.209)PAIR 84.169 1.1389000000000002e-11 74860000.0 80890.0 55353.0 84686.0 121470.0 100100.0 103610.0 80494.0 121560.0 84415.0 91232.0 True False 106611.33738347814 73244.7747630883 83563.00830715061 93466.96819279216 86202.84285177257 97131.2503210226 87657.81006245963 102775.69517090789 88877.00456336187 88037.99544885955 1.2109696141980841 0.83196777016164 0.9491698201567024 1.06166624667285 0.9791549933897233 1.103287845501267 0.9956815760688148 1.1674015820886032 1.009530079714158 1.0 16.425838676199717 -6.529003815360237 1.704483795678043 1.0612586213785327 0.9917792223559503 0.024766452427293473 0.10302051069014544 1.0095121362990667 5.9511311611522455 0.03881078901899642 0.042247588945507515 2.9579864799593997e-07 6.529003815360237 -0.06947939902258238 ESAAPAAAPTAEAPPPS(ph)VVTRPEPQALPSPAIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESAAPAAAPTAEAPPPSVVTRPEPQALPSPAIR 33 1 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 1 ESAAPAAAPT(0.086)AEAPPPS(0.346)VVT(0.346)RPEPQALPS(0.222)PAIR;ESAAPAAAPT(0.042)AEAPPPS(0.38)VVT(0.344)RPEPQALPS(0.235)PAIR 69.782 8.5194e-06 76726000.0 142839.0 152885.0 142918.0 144099.0 192386.0 164427.0 187294.0 171533.0 170148.0 127674.0 True False 167018.82150115303 168062.41241823477 146325.70713953354 136025.60020526126 154689.34435445655 155804.15866280964 169552.15642886588 167030.44050423673 172636.09261160862 150820.28553317217 1.1074028994887302 1.114322332861983 0.9701991122895065 0.9019052027675887 1.0256534378489384 1.0330451113523538 1.124199943193807 1.1074799382175895 1.1446476977636948 1.0 17.20247096053592 -7.165019012788446 4.995040809207536 1.102807006801742 1.0202123399938279 0.19277881570164346 0.06771121428061452 0.36149881118316535 14.440955570433637 0.02868301428685627 0.02197633411787319 6.838817072674904e-08 7.165019012788446 -0.08259466680791405 ESAAPAAAPTAEAPPPS(ph)VVTRPEPQALPSPAIR ddPTM_PC-9_Lapatinib_30min_R1 1 ESAAPAAAPTAEAPPPSVVTRPEPQALPSPAIR 33 1 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 1 ESAAPAAAPT(0.026)AEAPPPS(0.463)VVT(0.352)RPEPQALPS(0.159)PAIR 58.945 0.00033835 37670000.0 37896.0 37068.0 44281.0 30572.0 43213.0 47718.0 44533.0 37765.0 47877.0 43680.0 True False 37355.596090724735 36982.17132345111 40640.387109603056 32820.36686520233 40671.29630002681 45677.212376090974 46838.70083835749 39519.69976791062 42484.58809283928 51230.02980005849 0.7291738114640348 0.7218846342230488 0.7932922793177188 0.6406470383346305 0.7938956205717524 0.891610107477213 0.9142821314209739 0.7714166851385572 0.8292907159853101 1.0 15.644702110545207 -6.54185521324299 5.1920134044876995 0.8676242746354762 0.7250088595121448 0.5665743194297832 0.06550204184821026 0.14675742540746842 11.34947501836668 0.021409907137523183 0.022093572800978668 2.871737813399353e-07 6.54185521324299 -0.14261541512333142 ESAAPAAAPTAEAPPPSVVTRPEPQALPS(ph)PAIR ddPTM_PC-9_AZD4547_30min_R2 3 ESAAPAAAPTAEAPPPSVVTRPEPQALPSPAIR 33 1 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 1 ESAAPAAAPT(0.029)AEAPPPS(0.196)VVT(0.246)RPEPQALPS(0.529)PAIR;ESAAPAAAPT(0.003)AEAPPPS(0.185)VVT(0.185)RPEPQALPS(0.626)PAIR;ESAAPAAAPTAEAPPPS(0.003)VVT(0.009)RPEPQALPS(0.988)PAIR 74.382 3.9405e-08 176249000.0 106211.3 105541.8 151381.0 209026.0 184172.0 146190.0 118735.0 214831.0 134592.0 139357.0 True False 139984.2840677198 139656.122867612 149373.58902941164 160838.2851195075 158602.89684012672 137048.71618984969 129302.18497982656 181633.8052752659 141706.25834498616 134478.15384696942 1.0409444215527834 1.03850416497043 1.1107647209329823 1.1960179443163297 1.1793952571702484 1.019115092446952 0.961510708475126 1.3506565942447253 1.053749284112288 1.0 17.03701229854572 -5.2808819062723025 5.760976014775654 1.1188414248578062 1.0391855347062207 0.05592906620800786 0.10791440535233665 0.43513461051498337 53.5403269041277 0.028479625857400357 0.06501136543493197 5.2374283382469e-06 5.2808819062723025 -0.07965589015158558 ESAAPAAAPTAEAPPPSVVTRPEPQALPS(ph)PAIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESAAPAAAPTAEAPPPSVVTRPEPQALPSPAIR 33 1 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 1 ESAAPAAAPT(0.011)AEAPPPS(0.224)VVT(0.224)RPEPQALPS(0.54)PAIR;ESAAPAAAPT(0.006)AEAPPPS(0.241)VVT(0.241)RPEPQALPS(0.512)PAIR 61.111999999999995 0.00020419999999999998 81201000.0 84812.0 68249.0 101778.0 99389.0 102001.0 99084.0 132984.0 115968.0 99360.0 84051.0 True False 99168.99648664406 75024.30967807218 104204.77351521431 93820.55655348551 82014.63627030526 93887.86061258696 120386.79279921559 112923.9628782528 100812.95202934761 99288.78095264989 0.998793575015661 0.7556171901622072 1.049512064861677 0.9449260596544927 0.8260211826894869 0.9456039213268356 1.2124913977605103 1.137328525889601 1.015350889215012 1.0 16.599343090471443 -7.108889825776973 6.721063731137028 1.1018418040205502 0.9124962309297009 0.4373308905875255 0.09528977469041638 0.2204615670812575 11.911192668294886 0.03589619129640996 0.02779333539234793 7.782339526875266e-08 7.108889825776973 -0.18934557309084932 ESAAPAAAPTAEAPPPSVVTRPEPQALPS(ph)PAIR ddPTM_PC-9_Lapatinib_30min_R1 3 ESAAPAAAPTAEAPPPSVVTRPEPQALPSPAIR 33 1 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 1 ESAAPAAAPT(0.001)AEAPPPS(0.015)VVT(0.014)RPEPQALPS(0.971)PAIR;ESAAPAAAPT(0.006)AEAPPPS(0.325)VVT(0.325)RPEPQALPS(0.343)PAIR;ESAAPAAAPTAEAPPPS(0.011)VVT(0.011)RPEPQALPS(0.977)PAIR 82.086 7.627000000000001e-09 157077000.0 158696.0 146741.0 160965.0 130490.0 166150.0 162797.0 213176.0 185888.0 212629.0 156930.0 True False 156432.96593871783 146401.2302302399 147731.07904286872 140086.66990187927 156377.38366346818 155834.55180834225 224213.210201821 194525.03509750776 188680.4829373671 184055.14140391865 0.8499244560379734 0.7954204871080168 0.80264576102585 0.7611125059226231 0.8496224689550498 0.8466731796769271 1.2181849878878057 1.0568845489114176 1.025130194669748 1.0 17.489778525024505 -7.1371749483263285 6.224243038275423 1.0788307579264171 0.8115815836602591 0.8198737535607794 0.05924757428619651 0.09412102397085906 4.385894845075997 0.0227119194890038 0.017554273955322098 7.291637195778633e-08 7.1371749483263285 -0.267249174266158 ESADPLGAWLQDAR ddPTM_PC-9_AZD4547_30min_R2 2 ESADPLGAWLQDAR 14 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 108.98 0.004279600000000001 2078200.0 12514.400000000001 10756.8 11688.4 17810.2 17794.3 14252.9 12294.8 17624.0 10274.3 13017.1 False True 16493.71888430957 14233.725239311116 11533.404178935116 13704.333554847011 15323.868596975999 13361.663909859128 13389.013381816421 14900.615759230686 10817.378522600831 12561.375291096885 1.313050402689569 1.1331343033274024 0.9181641270689235 1.090989898579037 1.2199196538484989 1.0637102705887198 1.0658875379120423 1.1862248690071209 0.8611619565468962 1.0 13.61670680691789 -4.828929757884155 3.830787888431139 1.063852862862375 1.3257989721993688 0.3653858511344106 0.10349719708723006 0.25454191239671836 6.40052075358259 0.025648265980911824 0.16908554269999188 1.482757884713312e-05 4.828929757884155 0.2619461093369939 ESADPLGAWLQDAR ddPTM_PC-9_Lapatinib_30min_R1 4 ESADPLGAWLQDAR 14 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ;;; 207.95 2.9457e-10 10978200.0 46560.9 45893.5 53061.7 47491.8 48368.8 54468.4 45064.4 44303.0 49545.7 39797.1 False True 45896.93302777668 45787.23642043825 48699.171850085244 50984.50540000053 45523.84228071963 52138.91350404197 47397.61413019736 46361.47911605305 43965.34152664925 46675.97570869756 0.9833095576666068 0.9809593848920076 1.043345556481012 1.092307222846123 0.9753163504247168 1.1170396057586098 1.0154605963891041 0.9932621313669527 0.9419265662711532 1.0 15.510392560230954 -7.819413572046716 3.2523852982432957 0.9710252094091073 1.0325215645614998 0.21636772841233454 0.04596575264459231 0.3690556594142086 7.7988380072738845 0.02857982315989116 0.012761904734280698 1.515606391056129e-08 7.819413572046716 0.06149635515239249 ESAS(ph)PTIPNLDLLEAHTK ddPTM_PC-9_AZD4547_30min_R2 3 ESASPTIPNLDLLEAHTK 18 0 O75151 O75151 PHF2 Lysine-specific demethylase PHF2 1 ES(0.151)AS(0.844)PT(0.004)IPNLDLLEAHTK;ES(0.053)AS(0.875)PT(0.072)IPNLDLLEAHTK;ES(0.248)AS(0.735)PT(0.016)IPNLDLLEAHTK 138.77 2.2392e-05 56834300.0 158093.0 182430.0 205756.0 275900.0 241623.0 235769.0 181270.0 256375.0 175869.0 208194.0 True False 208363.28546132045 241396.92988691112 203027.5410014178 212295.51761250792 208077.81716657168 221026.32715893467 197402.678833479 216758.13466141417 185165.07629632053 200905.1914293212 1.037122455517149 1.2015465014592965 1.010563935939123 1.0566950316323402 1.0357015450234088 1.1001523932082766 0.9825663410142671 1.0789075838175644 0.9216540149061402 1.0 17.61615531851085 -6.686182819003598 0.38311637736907833 0.9802064510393863 1.1161220687643685 0.2578261421904028 0.06166987057354525 2.239635256479475 0.6622535679719501 0.06334299596799221 0.1190850959764331 2.059762660651027e-07 6.686182819003598 0.13591561772498217 ESAS(ph)PTIPNLDLLEAHTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESASPTIPNLDLLEAHTK 18 0 O75151 O75151 PHF2 Lysine-specific demethylase PHF2 1 ES(0.297)AS(0.499)PT(0.204)IPNLDLLEAHTK;ES(0.184)AS(0.809)PT(0.007)IPNLDLLEAHTK 147.03 4.5233e-05 33761000.0 123044.0 129024.0 128970.0 143853.0 178719.0 140915.0 145763.0 143941.0 125746.0 112842.0 True False 143872.9189702244 141832.6500300902 132045.1339214487 135793.38278771885 143700.29489507637 133525.16933332005 131955.2734072674 140162.70126809616 127584.7973619399 133299.36134321944 1.0793218926216768 1.0640159757772525 0.9905908969920617 1.0187099279348968 1.0780268821024326 1.001693991537733 0.9899167713752861 1.0514881681031087 0.9571298472573648 1.0 17.02431034271683 -1.5228787452803376 0.42605744170993354 1.0062302086804285 2.4229174297667497 0.33429056200726603 0.03281845670519115 102.53801193409234 1.298780081189765 0.022134581912965405 124.34727925066781 0.029999999999999995 1.5228787452803376 1.4166872210863213 ESAS(ph)PTIPNLDLLEAHTK ddPTM_PC-9_Lapatinib_30min_R1 4 ESASPTIPNLDLLEAHTK 18 0 O75151 O75151 PHF2 Lysine-specific demethylase PHF2 1 ES(0.043)AS(0.956)PT(0.002)IPNLDLLEAHTK;ES(0.173)AS(0.653)PT(0.173)IPNLDLLEAHTK;ES(0.019)AS(0.761)PT(0.22)IPNLDLLEAHTK;ES(0.242)AS(0.758)PTIPNLDLLEAHTK 173.81 1.5632e-08 75341000.0 166754.9 162063.4 172680.0 131543.5 158266.0 180447.7 153430.0 159053.5 186693.0 131971.0 True False 164376.9445468966 161688.1521544457 158482.91696407596 141217.6478062525 148957.10504292772 172730.37251513364 161373.85466124414 166443.70626334898 165665.668375555 154782.01150969625 1.0619899750856983 1.0446184965383838 1.0239104364795508 0.9123647278443979 0.9623670321250242 1.1159589595094066 1.042587915011913 1.0753427006142906 1.070316031945204 1.0 17.23987828820765 -6.753729720790774 24.99953437802983 1.0644092167786674 0.9998136521120387 0.2787534236909922 0.04789585024505377 241.7063853228958 783762.8153302101 0.017132792187333594 0.01682294418581477 1.763072937416216e-07 6.753729720790774 -0.06459556466662875 ESCS(ph)SPSTVGSSLTTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESCSSPSTVGSSLTTR 16 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;H0YEP9 E9PMC9 C11orf30;EMSY Protein EMSY 1 ES(0.134)CS(0.817)S(0.044)PS(0.002)T(0.004)VGSSLTTR 222.75 6.172399999999999e-24 10537000.0 49247.0 56636.0 61557.0 52205.0 64556.0 53781.0 50847.0 48287.0 48963.0 41424.0 True False 57583.54442741321 62258.447785715616 63024.75233622253 49280.123100893594 51906.71521912356 50960.629683960404 46030.40405959903 47019.51741430557 49678.99124610462 48933.84328779644 1.1767631675432677 1.2722983441041549 1.2879583556425909 1.0070764891909383 1.0607528804521373 1.0414189088775176 0.9406660292116992 0.9608793067359931 1.0152276606177388 1.0 15.57854497673891 -5.767652292810748 24.972976863552926 1.0034075043301203 1.2483358094936943 0.872822737343314 0.042320317110091994 47.875842344612344 192438.97877981386 0.012861885377091804 0.019630278897912048 1.7074488688286119e-06 5.767652292810748 0.244928305163574 ESCSS(ph)PSTVGSSLTTR ddPTM_PC-9_AZD4547_30min_R2 2 ESCSSPSTVGSSLTTR 16 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;H0YEP9 E9PMC9 C11orf30;EMSY Protein EMSY 1 ESCS(0.322)S(0.606)PS(0.055)T(0.018)VGSSLTTR;ES(0.003)CS(0.388)S(0.478)PS(0.035)T(0.035)VGS(0.048)S(0.014)LTTR 241.39 9.8007e-38 21600500.0 52772.0 49865.0 65706.0 95511.0 78124.0 78808.0 64473.0 81811.0 61418.0 64448.0 True False 69552.3982742109 65982.88608677751 64834.69550846225 73492.4145802401 67277.83111840053 73880.12330179689 70210.97209924938 69168.98977975622 64664.43009266788 62191.695136444454 1.118355081359618 1.0609597622643254 1.0424976416259315 1.1817078537416068 1.0817815943237667 1.1879419452984648 1.1289444988629296 1.1121901345188299 1.0397598899788534 1.0 15.92443432026855 -10.972507952855876 7.053143514656802 0.9999858755138595 1.1076011363693774 0.29412470580390737 0.049215508498795094 1.1098586051504634e-05 8.660687340773515e-07 0.04838354081725752 0.011733192751883809 1.0653493546758435e-11 10.972507952855876 0.10761526085551787 ESCSS(ph)PSTVGSSLTTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESCSSPSTVGSSLTTR 16 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;H0YEP9 E9PMC9 C11orf30;EMSY Protein EMSY 1 ESCS(0.009)S(0.989)PS(0.001)T(0.001)VGSSLTTR 172.57 1.7989e-05 9924500.0 21016.0 26631.0 24240.0 24668.0 29732.0 18981.0 22764.0 19769.0 18297.0 18899.0 True False 24573.593715079416 29274.7496818524 24817.973530711923 23285.931934735054 23906.228032947845 17985.602945859195 20607.62912291213 19250.084696986916 18564.559010476816 22325.239095598325 1.1007090947538556 1.3112849343514648 1.1116554418270517 1.0430316931891734 1.070816215252146 0.8056174838192556 0.9230642070469544 0.8622565973227265 0.831550288486587 1.0 14.446388005744184 -6.199408100505355 1.1414987961261005 0.8780470274012613 1.2015044207237646 0.6898779134281129 0.08204703302177126 0.25388445084125655 0.6821002879068526 0.032693911836963095 0.05184749769314626 6.318178618502333e-07 6.199408100505355 0.32345739332250334 ESCSS(ph)PSTVGSSLTTR ddPTM_PC-9_Lapatinib_30min_R1 2 ESCSSPSTVGSSLTTR 16 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;H0YEP9 E9PMC9 C11orf30;EMSY Protein EMSY 1 ESCS(0.031)S(0.856)PS(0.055)T(0.055)VGS(0.001)S(0.002)LTTR;ESCS(0.016)S(0.977)PS(0.003)T(0.003)VGSSLTTR 255.91 2.3935e-57 26498000.0 77582.0 91799.0 100132.0 77020.0 94952.0 98415.0 99761.0 101784.0 90851.0 78231.0 True False 76475.66645320374 91586.4450556139 91899.53348069775 82684.30773118805 89367.11004281457 94206.01986657013 104926.13644567813 106513.25622076009 80618.40367655753 91753.1241137451 0.8334938694664815 0.9981833963721545 1.0015956880854666 0.901160680138645 0.9739952825151478 1.026733648325524 1.14357017768248 1.160867896865474 0.8786447813658746 1.0 16.485469660847798 -6.764959025251773 3.139098062620893 1.061427189074834 0.9431577496945281 0.24959784823258446 0.08638280479779589 0.3330311396737021 6.795478282465206 0.031504587658261744 0.02925784572282149 1.7180704757571242e-07 6.764959025251773 -0.11826943938030576 ESDFSDTLS(ph)PSKEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESDFSDTLSPSKEK 14 1 A0A590UJP6;H7C5G9;H7BZW9;H7BZK0;A0A590UJS6;A0A590UJU9;H7C3M8;A0A5F9VB99;A0A590UJK3;Q14BN4-4;Q14BN4-6;Q14BN4-2;Q14BN4-3;Q14BN4 A0A590UJP6 SLMAP Sarcolemmal membrane-associated protein 1 ESDFS(0.019)DT(0.142)LS(0.813)PS(0.027)KEK;ESDFS(0.001)DT(0.006)LS(0.92)PS(0.073)KEK 64.327 0.019578 12047200.0 62267.0 68487.0 49637.0 61929.0 75636.0 54539.0 69590.0 56558.0 46213.0 44401.0 True False 72807.57327069135 75285.936745185 50820.534329370785 58459.318906526925 60815.66875756904 51678.87882957771 62997.931412030244 55073.41242815447 46888.77769859344 52450.54982187742 1.388118399481923 1.435369829312691 0.9689228140020993 1.1145606500800342 1.1594858197692806 0.9852876472235217 1.2010919165951899 1.0500063891643523 0.8939616049369965 1.0 15.678670275729273 -5.254905241204207 24.98718523929803 1.0582279609013505 1.4117441595358302 0.729469145109625 0.08870751284418836 257.5501641904523 984890.0790309395 0.022628565726513748 0.056936750079268926 5.56025563359684e-06 5.254905241204207 0.3535161986344797 ESDFSDTLS(ph)PSKEK ddPTM_PC-9_Lapatinib_30min_R1 1 ESDFSDTLSPSKEK 14 1 A0A590UJP6;H7C5G9;H7BZW9;H7BZK0;A0A590UJS6;A0A590UJU9;H7C3M8;A0A5F9VB99;A0A590UJK3;Q14BN4-4;Q14BN4-6;Q14BN4-2;Q14BN4-3;Q14BN4 A0A590UJP6 SLMAP Sarcolemmal membrane-associated protein 1 ESDFSDTLS(0.897)PS(0.103)KEK 84.195 0.003483 9643500.0 52309.0 75910.0 52956.0 48777.0 52190.0 56799.0 53884.0 47181.0 54019.0 37992.0 True False 51563.064067704225 75734.23505889637 48602.162096071486 52364.22329530206 49120.286809487865 54369.83917493589 56673.849863563104 49373.20150270859 47934.81137471197 44558.86657884208 1.1571897587760447 1.6996445572710623 1.0907405378023975 1.1751695524537018 1.102368407925611 1.2201800303590389 1.2718871509733058 1.1080443757551164 1.0757637043998085 1.0 15.44342491559633 -1.5228787525564298 0.15200485986152232 0.9810725781225696 2.4772503072319765 0.2529052481762618 0.15985704901401915 90.6740846415971 0.903900734089023 0.5441218869639608 29.993228449681347 0.029999999497385358 1.5228787525564298 1.496177729109407 ESDKEDGRES(ph)PSYDTPSQR ddPTM_PC-9_AZD4547_30min_R2 1 ESDKEDGRESPSYDTPSQR 19 2 Q9Y6M7-7;Q9Y6M7-2;C9JRP1;Q9Y6M7;Q9Y6M7-13;Q9Y6M7-9;Q9Y6M7-11;Q9Y6M7-6;Q9Y6M7-14;Q9Y6M7-12;Q9Y6M7-10;Q9Y6M7-8;A0A0A0MST8;E9PFN4 Q9Y6M7-7 SLC4A7 Sodium bicarbonate cotransporter 3;Anion exchange protein 1 ES(0.001)DKEDGRES(0.924)PS(0.067)Y(0.004)DT(0.003)PS(0.001)QR 74.214 0.012426999999999999 5419500.0 13473.0 20997.0 19399.0 14402.0 17743.0 13943.0 16388.0 19200.0 15761.0 14065.0 True False 17757.133744190905 27783.86963128587 19141.75658491857 11081.841408681918 15279.690716473528 13071.14200584904 17846.50025223731 16233.081172107883 16594.094283280785 13572.588631052806 1.3083085494512265 2.047057520605833 1.4103246702050656 0.8164869436422546 1.12577571838544 0.9630544593345662 1.3148928872275845 1.1960195371255944 1.2226182296069195 1.0 13.728408284463827 -5.524429289268662 23.64661594133198 1.1055036469356048 1.6904350829620705 0.5544033191846689 0.21314723994559429 15.908402558893735 242610.60566613503 0.05509912305572748 0.09649839238821101 2.989308318974109e-06 5.524429289268662 0.5849314360264657 ESDQLTVSDQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESDQLTVSDQR 11 0 Q9P2N4-2;Q9P2N4-1;Q9P2N4-4;Q9P2N4 Q9P2N4-2 ADAMTS9 A disintegrin and metalloproteinase with thrombospondin motifs 9 0 93.667 0.032147 3477100.0 5352.3 3857.7 9105.8 8589.7 9324.8 9795.8 7792.1 6848.3 6617.8 7114.0 False True 6258.338677256353 4240.666961348882 9322.916805938807 8108.4469571831405 7497.672378636893 9282.091003479656 7053.975878081337 6668.539381373638 6714.572805352432 8403.711885606981 0.7447112374205731 0.504618318556573 1.1093808227654909 0.9648649391550964 0.892185796074011 1.104522754924175 0.839388114930816 0.7935230850542164 0.7990008340067519 1.0 13.036810985900647 -5.254916135104914 24.999790540648497 0.9322529911603279 0.6246647716998797 0.5232672359296971 0.11948141450480967 416.2097910432942 1595078.993517754 0.031549037272926704 0.07941426175949809 5.560116161152224e-06 5.254916135104914 -0.30758821946044823 ESDQTLAALLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 7 ESDQTLAALLSPK 13 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ES(0.003)DQT(0.001)LAALLS(0.996)PK 181.75 1.3257e-05 262473900.0 301657.0 322180.0 261822.0 248368.0 268197.0 306621.0 332064.0 301868.0 299521.6 277783.0 True False 397577.65114461473 426318.38442671235 258350.06920854416 191110.59484734843 230962.4759672016 287447.940398439 361617.0527067939 255221.23683655573 315353.7002905344 268057.901720565 1.4831782558645359 1.5903966333032213 0.9637845687453724 0.7129452018413928 0.8616141306961612 1.0723352624691027 1.3490259021864572 0.9521123428870575 1.1764387405347692 1.0 18.03218513744281 -5.2620825475755 24.995536412006366 1.0076000364731965 1.5367874823823793 0.6224476476128937 0.16377011194025343 37.43348972609616 1454858.1359498063 0.046921987430097054 0.10807064039779446 5.4691199990964644e-06 5.2620825475755 0.5291874459091828 ESDQTLAALLS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 11 ESDQTLAALLSPK 13 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK 186.42 4.0237e-05 223522600.0 345571.10000000003 422687.2 289095.5 367704.10000000003 351150.1 230388.0 375311.6 290057.7 261330.8 258529.19999999998 True False 404069.4618896601 464648.79177361354 295988.6331207891 347102.83138977655 282344.75865708437 218306.04770510545 339759.368227321 282443.9927165369 265152.26856069925 305398.4974439788 1.323089226933021 1.5214508115215828 0.9691882428959369 1.1365571025883907 0.9245125991783135 0.7148235814262666 1.112511590826164 0.9248375322093634 0.8682173317153855 1.0 18.2203334385511 -5.2702373156799664 24.287128537031847 0.9558994850255924 1.4222700223225224 0.7030489123006991 0.12112612481976523 202.9034060218569 560126.5701557619 0.03216134337471102 0.06869860083859824 5.367384211219254e-06 5.2702373156799664 0.46637053729693 ESDQTLAALLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 7 ESDQTLAALLSPK 13 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 ESDQTLAALLS(1)PK;ESDQT(0.03)LAALLS(0.97)PK;ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQT(0.001)LAALLS(0.999)PK;ESDQTLAALLS(1)PK 192.4 5.3927e-06 207750200.0 229113.4 360748.0 252752.3 305623.2 349430.3 309952.3 340892.2 340225.1 285714.0 307625.0 True False 225846.20090174774 359912.71017029195 231971.98154609278 328099.7496571077 328877.49676040205 296696.3626631008 358541.93011765485 356033.200198792 253533.88061819808 360797.5713654539 0.6259637503850791 0.9975474857222205 0.6429421923994246 0.9093734983176304 0.9115291311849774 0.8223347001484537 0.9937481806231054 0.9867948912498747 0.7027039557353123 1.0 18.460830101858242 -5.875577677762367 21.803747616838013 0.9039291504847105 0.7790382223988603 0.21650200148759335 0.12692649084423216 5.615249591997427 1044.67837034895 0.03383191349676869 0.05018094656583914 1.3317488248711158e-06 5.875577677762367 -0.12489092808585012 ESDRVYLDLT(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 1 ESDRVYLDLTPVK 13 1 Q8N4X5-2;Q8N4X5;Q8N4X5-4;Q8N4X5-3 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 ESDRVYLDLT(0.999)PVK 71.354 0.018808000000000002 6008000.0 40712.0 28115.0 59294.0 89641.0 84610.0 52675.0 42802.0 59697.0 46030.0 62753.0 True False 53657.569137794126 37202.62393120929 58507.722817988644 68975.65238964425 72863.36197490974 49381.22392297915 46611.29508153907 50472.200350589796 48463.0518278925 60556.03657052661 0.8860812592201575 0.6143503775693979 0.9661749039643241 1.1390384228550317 1.2032386216368274 0.8154632753328778 0.7697216945044482 0.8334792567179876 0.800300920808283 1.0 15.885983162693998 ESDRVYLDLT(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 1 ESDRVYLDLTPVK 13 1 Q8N4X5-2;Q8N4X5;Q8N4X5-4;Q8N4X5-3 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 ESDRVYLDLT(1)PVK 85.988 0.0056356999999999996 3703600.0 56647.0 31754.0 40292.0 34795.0 34883.0 30098.0 20193.0 17821.0 31254.0 22393.0 True False 55839.20339221246 31680.475563959928 36979.34729161778 37353.940372717356 32831.2505226167 28810.778701864823 21238.494734892185 18649.02871875903 27733.84540078949 26263.60021320307 2.1261062055057223 1.20625029724728 1.4080075462399004 1.4222703692366983 1.2500666418959567 1.096985122678697 0.8086665408581457 0.7100712989601444 1.0559803368788452 1.0 14.68077707391127 -1.5228787452803676 0.32258800285995 0.8619341421048712 11.340346264310336 0.7187934572727279 0.19959613193942738 32.34993385759337 0.4614852675028733 0.19542758580086256 200.53208210580954 0.029999999999997924 1.5228787452803676 10.478412122205464 up ESDTKNEVNGTSEDIKS(ph)EGDTQSN ddPTM_PC-9_AZD4547_30min_R2 1 ESDTKNEVNGTSEDIKSEGDTQSN 24 2 O95232 O95232 LUC7L3 Luc7-like protein 3 1 ESDTKNEVNGT(0.007)S(0.041)EDIKS(0.409)EGDT(0.409)QS(0.133)N 53.401 0.035230000000000004 4829400.0 20978.0 22393.0 19149.0 21055.0 22119.0 17920.0 22898.0 19929.0 27047.0 24071.0 True False 27648.567630493348 29631.09933101796 18895.071748265666 16201.095046507282 19048.158651731836 16799.45956715305 24935.87764069627 16849.43097286135 28476.649202455144 23228.281616642176 1.1902975901017234 1.275647498168285 0.8134511222185316 0.6974728184326737 0.8200416615443717 0.7232329900424869 1.0735136611582436 0.7253843074121066 1.2259473030520136 1.0 14.503594809854325 -5.260404000834242 24.99913928306378 0.8670277461871073 1.2329725733947121 0.41711758087119555 0.1635085445588474 76.94326708906763 1857730.8518523267 0.04085265420797914 0.09628979372130059 5.490299031949846e-06 5.260404000834242 0.3659448272076048 ESDTKNEVNGTSEDIKS(ph)EGDTQSN ddPTM_PC-9_Lapatinib_30min_R1 1 ESDTKNEVNGTSEDIKSEGDTQSN 24 2 O95232 O95232 LUC7L3 Luc7-like protein 3 1 ESDTKNEVNGTS(0.001)EDIKS(0.361)EGDT(0.361)QS(0.276)N 65.171 0.0037604 5456900.0 19801.0 18643.0 19175.0 19132.0 21447.0 21467.0 20391.0 21115.0 20217.0 17545.0 True False 19518.63410894131 18599.833278922513 17598.505517640504 20539.03110248107 20185.52962642433 20548.906452021147 21446.74620607074 22096.079984097247 17939.948565551964 20577.62987275702 0.9485365530255878 0.9038860837684257 0.8552250976648862 0.998124236342347 0.9809453154344175 0.9986041433870914 1.0422359785207505 1.0737913025323933 0.8718180216324565 1.0 14.328789202027522 -5.78138450249134 24.228766821038203 0.999672281991869 0.9026829506108291 0.3859890851157711 0.053256553677596304 157.3170797505739 191103.71675085163 0.014897770171653791 0.022133856024668903 1.6543046767624783e-06 5.78138450249134 -0.09698933138103982 ESDTKNEVNGTSEDIKSEGDT(ph)QSN ddPTM_PC-9_Lapatinib_30min_R1 1 ESDTKNEVNGTSEDIKSEGDTQSN 24 2 O95232 O95232 LUC7L3 Luc7-like protein 3 1 ESDTKNEVNGTS(0.001)EDIKS(0.239)EGDT(0.602)QS(0.157)N 64.002 0.012659 15898000.0 36905.0 48092.0 29522.0 43496.0 40282.0 37953.0 37127.0 35875.0 34064.0 35252.0 True False 36378.72793245187 47980.645928763675 27094.815118215545 46694.84093840247 37912.691957459116 36329.83866276419 39049.254396193806 37541.88346812639 30227.3536101777 41345.261229662596 0.8798766013443989 1.1604871876910676 0.6553306065164425 1.1293879769926787 0.9169779275758735 0.8786941376657657 0.9444674730505379 0.9080093425844042 0.7310959638704978 1.0 15.335434364514613 -7.201758982106576 1.1683381455385164 0.8737659937438738 0.951705392580512 0.030663726187707963 0.14532613154358295 1.8258869796251824 4.909030706336454 0.09087916713189641 0.054544909066518966 6.284070054575913e-08 7.201758982106576 0.07793939883663825 ESDTKNEVNGTSEDIKSEGDTQS(ph)N ddPTM_PC-9_AZD4547_30min_R2 1 ESDTKNEVNGTSEDIKSEGDTQSN 24 2 O95232 O95232 LUC7L3 Luc7-like protein 3 1 ESDTKNEVNGTSEDIKSEGDT(0.076)QS(0.924)N 98.62700000000001 1.2430999999999998e-05 12486000.0 51246.0 49067.0 55855.0 62192.0 58725.0 62704.0 63477.0 60595.0 60181.0 71966.0 True False 67541.16201698271 64926.94819251811 55114.32620499133 47854.595256821674 50572.047417286194 58783.10896756496 69126.33002875696 51231.435084576915 63362.04479805342 69446.49224474558 0.9725640537602959 0.9349204847337783 0.7936228947425543 0.6890858517111413 0.7282160089390627 0.8464518086874657 0.9953898000368356 0.737710911359287 0.9123865403417476 1.0 16.083614204801265 -9.953658879589886 10.558119094541036 0.9999999536498123 0.8398957207438547 0.1692225655533537 0.10193418788048847 0.0 0.0 0.10510379710153861 0.02549141512371359 1.1126052897467936e-10 9.953658879589886 -0.16010423290595766 ESDTKNEVNGTSEDIKSEGDTQS(ph)N ddPTM_PC-9_Lapatinib_30min_R1 4 ESDTKNEVNGTSEDIKSEGDTQSN 24 2 O95232 O95232 LUC7L3 Luc7-like protein 3 1 ESDTKNEVNGTSEDIKS(0.004)EGDT(0.053)QS(0.943)N;ESDTKNEVNGTSEDIKS(0.053)EGDT(0.053)QS(0.893)N;ESDTKNEVNGTSEDIKSEGDT(0.004)QS(0.996)N;ESDTKNEVNGTSEDIKSEGDT(0.013)QS(0.986)N 110.12 1.8834e-06 93586000.0 247583.0 264231.0 253560.0 243672.0 258493.0 246132.0 241645.0 250488.0 254469.0 226920.0 True False 244052.42101883894 263619.1893538045 232713.27556990445 261592.4517459625 243288.94995679153 235605.5081217157 254156.19572193423 262126.58693140198 225808.02154263444 266142.81964810606 0.9169979537359865 0.9905177592330378 0.8743924629550324 0.9829025336540732 0.9141293019983334 0.8852596828771606 0.9549616858271038 0.9849094831037923 0.848446791993854 1.0 18.021841118296273 -10.758293835990255 4.932972260522711 1.0000117193717193 0.9307242904647559 0.17085488273001037 0.047217594660841196 5.73310793056286e-06 8.885901765389643e-07 0.043068474423317585 0.010443872679588788 1.7446413599259363e-11 10.758293835990255 -0.06928742890696338 ESEAVEWQQK ddPTM_PC-9_Lapatinib_30min_R1 1 ESEAVEWQQK 10 0 P26038 P26038 MSN Moesin 0 152.97 0.00079435 7104700.0 39473.0 40296.0 34848.0 38084.0 37145.0 33567.0 27827.0 31374.0 32500.0 33473.0 False True 38910.10778153834 40202.69708777885 31982.93195717007 40884.82440449971 34960.20412987979 32131.41765849878 29267.745901443315 32831.75057641805 28839.50775982781 39258.76345003112 0.9911190359080833 1.0240438963124545 0.8146698761380554 1.0414190568314323 0.8905070118771681 0.8184521068626096 0.7455086031605541 0.8362910008158199 0.7346005127373657 1.0 15.260727111889887 -6.582826481053185 3.6592347379010848 0.8120679418548353 0.961850436095366 0.3482878005579212 0.08914027652478343 0.23860502598290487 6.530033781878559 0.029013293338078557 0.029576769063440447 2.613205231460074e-07 6.582826481053185 0.1497824942405307 ESEDKPEIEDVGS(ph)DEEEEK ddPTM_PC-9_AZD4547_30min_R2 4 ESEDKPEIEDVGSDEEEEK 19 1 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 ESEDKPEIEDVGS(1)DEEEEK;ESEDKPEIEDVGS(1)DEEEEK;ESEDKPEIEDVGS(1)DEEEEK;ESEDKPEIEDVGS(1)DEEEEK 144.43 1.2455e-05 261353000.0 301363.0 438672.0 212616.0 117472.0 187332.0 290482.0 402160.0 318958.0 351189.0 217310.0 True False 397190.16526019527 580464.1453014918 209796.5729191733 90390.64532430796 161324.18538569662 272318.11461973994 437951.4609128488 269670.3700256872 369752.1335734464 209702.04304401577 1.8940691253867583 2.7680423942252883 1.00045078185117 0.4310432269147481 0.7693019249785525 1.2985954293377164 2.08844632391552 1.2859692071244355 1.7632261860979421 1.0 17.677981391546624 -10.317060076511599 18.296203099981582 1.000000000757847 1.4570377298556094 0.04588319038995403 0.6473517710328233 0.0 0.0 0.6924727499064256 0.16794931121918327 4.818811337803204e-11 10.317060076511599 0.4570377290977625 ESEDKPEIEDVGS(ph)DEEEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ESEDKPEIEDVGSDEEEEK 19 1 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 ESEDKPEIEDVGS(1)DEEEEK;ESEDKPEIEDVGS(1)DEEEEK;ESEDKPEIEDVGS(1)DEEEEK;ESEDKPEIEDVGS(1)DEEEEK 183.56 4.338399999999999e-11 138464000.0 112360.8 312882.0 110628.2 86178.2 106775.1 65060.1 134281.9 62119.8 65819.2 86336.2 True False 131381.26421304204 343942.8571948986 113265.99584778497 81349.91484749399 85853.28564646875 61648.233824239695 121561.74631523318 60489.221071368636 66781.6812823072 101988.26962301688 1.2881997576649904 3.3723766318050856 1.110578660334707 0.797639916317737 0.8417956885023299 0.6044639648472555 1.191918901698857 0.5930997877987071 0.6547976696649023 1.0 16.63804370183064 -5.4405926444724795 7.378684459709381 0.8142754351930256 2.325500595409713 0.5920850297711502 0.49701562629859236 0.1600741303671641 12.572504088787836 0.11871238263921685 0.248044649808607 3.6258293115768237e-06 5.4405926444724795 1.5112251602166875 ESEDKPEIEDVGS(ph)DEEEEK ddPTM_PC-9_Lapatinib_30min_R1 12 ESEDKPEIEDVGSDEEEEK 19 1 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 ESEDKPEIEDVGS(1)DEEEEK;ESEDKPEIEDVGS(1)DEEEEK;ESEDKPEIEDVGS(1)DEEEEK;ESEDKPEIEDVGS(1)DEEEEK;ESEDKPEIEDVGS(1)DEEEEK;ESEDKPEIEDVGS(1)DEEEEK;ESEDKPEIEDVGS(1)DEEEEK;ESEDKPEIEDVGS(1)DEEEEK;ES(0.001)EDKPEIEDVGS(0.999)DEEEEK;ESEDKPEIEDVGS(1)DEEEEK;ESEDKPEIEDVGS(1)DEEEEK;ESEDKPEIEDVGS(1)DEEEEK 189.99 1.4047000000000001e-11 522649300.0 351527.19999999995 676559.7 286692.80000000005 411033.00000000006 486275.69999999995 381274.8 587310.4 612370.6 369993.30000000005 516361.7 True False 346514.35766580724 674993.167582355 263122.02465021197 441261.73798589344 457673.91938081046 364968.5655989693 617718.4587801422 640823.5736447847 328320.7583518247 605614.1318362837 0.5721701979033091 1.1145598031798019 0.4344714081430022 0.7286186282475657 0.7557186916908569 0.6026420891011037 1.019986863429288 1.0581384085304324 0.5421286279372688 1.0 19.20803934503828 -7.261264529946604 24.99989047429249 0.909908340101106 0.7117232279015226 0.18003095696089133 0.21218118672183653 29.363403891970528 4198817.168262119 0.08218738525152346 0.059594484197133736 5.479431096211638e-08 7.261264529946604 -0.19818511219958335 ESEDKPEIEDVGS(ph)DEEEEKK ddPTM_PC-9_AZD4547_30min_R2 3 ESEDKPEIEDVGSDEEEEKK 20 2 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 ESEDKPEIEDVGS(1)DEEEEKK;ESEDKPEIEDVGS(1)DEEEEKK;ESEDKPEIEDVGS(1)DEEEEKK 78.122 0.00098286 264758200.0 374332.0 554234.0 241303.0 146590.0 222583.0 363767.0 505500.0 330421.0 433947.0 311452.0 True False 493361.7894107093 733379.301863413 238103.16455542075 112795.94029292343 191681.1925122486 341020.5919846304 550488.5207167406 279362.02676922176 456884.55249964085 300548.16027861065 1.6415398748518666 2.440139048542384 0.7922296524280739 0.37530071782292945 0.637771970836749 1.1346620510619712 1.8316150070805064 0.9295083573635947 1.5201708507418747 1.0 18.19723666346973 ESEDKPEIEDVGS(ph)DEEEEKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ESEDKPEIEDVGSDEEEEKK 20 2 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 ESEDKPEIEDVGS(1)DEEEEKK;ESEDKPEIEDVGS(1)DEEEEKK;ESEDKPEIEDVGS(1)DEEEEKK;ESEDKPEIEDVGS(1)DEEEEKK 128.51 7.708199999999999e-05 60236600.0 275360.0 708673.0 215168.0 254204.0 225134.0 139967.0 327342.0 130691.0 151624.0 188052.0 True False 321973.0093920945 779025.3719833065 220298.4211491844 239961.7740204873 181020.6088379419 132626.88412217877 296333.79600915057 127260.49972856084 153841.21415557395 222144.33898118755 1.4493865154014167 3.5068432333505415 0.9916904574725198 1.0802065680404696 0.814878333916363 0.5970302224690514 1.3339696044842528 0.5728730262144469 0.6925281772253584 1.0 17.76113785131104 -5.371182649063166 7.736949880448487 0.8728078661124032 2.471745731564257 0.6104521819841839 0.5094264333169912 0.14898861969704547 9.29104838416046 0.12271096808191936 0.25677609709671906 4.254194589663952e-06 5.371182649063166 1.5989378654518538 ESEDKPEIEDVGS(ph)DEEEEKK ddPTM_PC-9_Lapatinib_30min_R1 6 ESEDKPEIEDVGSDEEEEKK 20 2 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 ESEDKPEIEDVGS(1)DEEEEKK;ESEDKPEIEDVGS(1)DEEEEKK;ESEDKPEIEDVGS(1)DEEEEKK;ESEDKPEIEDVGS(1)DEEEEKK;ESEDKPEIEDVGS(1)DEEEEKK;ESEDKPEIEDVGS(1)DEEEEKK 121.5 2.7893000000000002e-05 1581604000.0 293548.0 678355.0 263349.0 409109.0 489347.0 369670.0 626820.0 630451.0 314746.0 513508.0 True False 289361.95168988965 676784.3106755054 241697.46177653712 439196.24060761736 460564.5715532185 353860.0758428591 659273.6725461853 659744.0550345308 279295.99105768517 602267.1735935998 0.4804544633627109 1.1237277081486572 0.4013126937242485 0.729238218292767 0.7647180383502025 0.5875466758904548 1.0946531729638191 1.0954341925992392 0.46374101611945 1.0 19.200044101804785 -7.250953681435304 24.911119326821737 0.9214099505741697 0.6945450049211901 0.17374812496656156 0.24688645121527875 1234.1253760133325 2931945.061949345 0.09170299187112806 0.07025219264968231 5.611078163571645e-08 7.250953681435304 -0.22686494565297965 ESEDKPEIEDVGS(ph)DEEEEKKDGDK ddPTM_PC-9_AZD4547_30min_R2 2 ESEDKPEIEDVGSDEEEEKKDGDK 24 3 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 ESEDKPEIEDVGS(1)DEEEEKKDGDK;ESEDKPEIEDVGS(1)DEEEEKKDGDK 74.657 0.00024595 55631000.0 135918.0 182001.0 60662.0 39217.0 60730.0 91026.0 153383.0 101639.0 128929.0 87298.0 True False 179137.09672997432 240829.26402646385 59857.58224415333 30176.126546610096 52298.687776105384 85334.12983033895 167033.78985775704 85933.02798186842 135743.92372622987 84241.72359144321 2.12646523709268 2.8587884216904356 0.7105455550084842 0.358208797969979 0.6208169247550579 1.0129675200402322 1.9827916943846027 1.020076801830738 1.611362136707492 1.0 16.362247333854548 -2.572282485783438 10.166337532027878 1.318618471676258 1.323948234685643 0.0 0.7493129232891761 0.0 0.0 0.187188256528898 0.0 0.0026774262329667077 2.572282485783438 0.005329763009385147 ESEDKPEIEDVGS(ph)DEEEEKKDGDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESEDKPEIEDVGSDEEEEKKDGDK 24 3 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 ESEDKPEIEDVGS(1)DEEEEKKDGDK 65.887 0.0010356 6167600.0 24454.0 51249.0 15464.0 19652.0 16723.0 10440.0 28415.0 12346.0 14201.0 17571.0 True False 28593.5792114842 56336.662027158316 15832.720407546576 18550.962152643646 13446.248197059964 9892.508021430373 25723.325493215085 12021.930581668292 14408.662759347486 20756.483208040536 1.3775734032057885 2.7141718306757725 0.7627843430342468 0.8937430279835398 0.6478095572496225 0.476598464310094 1.2392911282413448 0.5791891844670152 0.6941764948777996 1.0 14.341274406669472 -5.281490123949045 24.730544754418936 0.7756216152872153 2.045872550158748 0.6570373706459491 0.36382278841140897 325.25310276390843 401166.127669657 0.08818102639050329 0.18394438579136085 5.230098595252862e-06 5.281490123949045 1.2702509348715327 ESEDSETQPFDTHLEAYGPCLS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 5 ESEDSETQPFDTHLEAYGPCLSPPR 25 0 Q14676;Q14676-3 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 ESEDSETQPFDTHLEAYGPCLS(1)PPR;ESEDSETQPFDTHLEAYGPCLS(1)PPR;ESEDSETQPFDT(0.032)HLEAY(0.159)GPCLS(0.809)PPR;ESEDSETQPFDTHLEAY(0.027)GPCLS(0.973)PPR;ESEDSETQPFDTHLEAYGPCLS(1)PPR 155.92 7.8302e-08 188656200.0 58436.200000000004 59970.2 100491.7 131072.9 104445.1 89529.1 74156.2 103737.7 76946.0 82617.7 True False 77017.696051532 79354.39436882123 99159.1143978897 100856.06796111805 89944.70071865829 83930.83122397342 80755.95814040514 87707.42212019676 81013.20847162764 79725.27946987057 0.9660385835416003 0.9953479611044888 1.2437600100901933 1.2650450225042251 1.1281829466982276 1.0527505426392665 1.0129278777997144 1.1001205979258155 1.0161545874824283 1.0 16.282749629274896 -6.79532071193206 5.303687956537634 1.040159779730725 1.1279427147115164 0.17103813547088664 0.09087297919588426 0.3870218410666352 27.284940169012234 0.03599815507817791 0.032572383034494605 1.6020618846989962e-07 6.79532071193206 0.08778293498079148 ESEDSETQPFDTHLEAYGPCLS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 ESEDSETQPFDTHLEAYGPCLSPPR 25 0 Q14676;Q14676-3 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 ESEDSETQPFDTHLEAYGPCLS(1)PPR;ESEDSETQPFDT(0.005)HLEAY(0.008)GPCLS(0.987)PPR;ESEDSETQPFDTHLEAYGPCLS(1)PPR;ESEDSETQPFDTHLEAYGPCLS(1)PPR;ESEDSETQPFDTHLEAYGPCLS(1)PPR;ESEDSETQPFDT(0.001)HLEAY(0.004)GPCLS(0.994)PPR 121.3 1.9481e-09 173211600.0 113415.3 107165.7 121877.6 143925.1 165311.0 125429.1 137691.0 134463.8 111206.5 108365.5 True False 132614.27023571782 117804.40246256202 124783.62420737193 135861.4432584697 132919.4962449428 118851.37719068906 124647.91168348695 130934.26772617275 112832.68468047169 128011.307329174 1.0359574712779673 0.9202655993476773 0.9747859529822451 1.0613237696972306 1.0383418388435615 0.9284443669110364 0.9737257925423863 1.0228336110143967 0.8814274850762104 1.0 16.965911724562346 -6.761977012738994 24.999999941457613 0.9634908276521129 1.0026888419018012 0.1582097284483447 0.051293320724172364 34.05076771457112 1583330.82922331 0.018046822140056915 0.01687971545839699 1.7299079210335623e-07 6.761977012738994 0.03919801424968827 ESEDSETQPFDTHLEAYGPCLS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 4 ESEDSETQPFDTHLEAYGPCLSPPR 25 0 Q14676;Q14676-3 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 ESEDSETQPFDTHLEAYGPCLS(1)PPR;ESEDSETQPFDTHLEAY(0.005)GPCLS(0.995)PPR;ESEDSETQPFDTHLEAY(0.034)GPCLS(0.966)PPR;ESEDSETQPFDTHLEAYGPCLS(1)PPR 153.18 5.9427e-08 166793000.0 112206.7 134908.1 155592.0 120941.4 143037.0 154326.8 144085.0 131150.0 156272.0 105588.3 True False 110606.61188181119 134595.7285831789 142799.82636248876 129835.83400468348 134623.84488156182 147726.60251734167 151545.01628668045 137243.70778661408 138671.00174288652 123839.09696743375 0.8931477585862698 1.0868597387994021 1.1531077814629185 1.048423617291288 1.087086777748098 1.1928914707460252 1.223725140102827 1.108242155728133 1.119767546264918 1.0 16.91810733096269 -4.767393907118093 3.5063512567431143 1.1236013436034527 0.8613541250241004 0.5350021524582768 0.06184368392361996 0.23636967621665803 4.713167615781157 0.015997343738748268 0.16923634645597566 1.7084650263998132e-05 4.767393907118093 -0.2622472185793523 ESEEGNPVRGSEEDS(ph)PKK ddPTM_PC-9_Lapatinib_30min_R1 2 ESEEGNPVRGSEEDSPKK 18 2 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 ESEEGNPVRGSEEDS(1)PKK;ESEEGNPVRGSEEDS(1)PKK 74.444 0.017672 29622000.0 29235.0 28370.0 20616.6 28530.0 26668.0 24473.0 23044.0 20661.1 17911.4 22498.1 True False 28818.10353895761 28304.311008047596 18921.58273037743 30628.191373290007 25099.440671305267 23426.3468393494 24237.105564842033 21621.090133053825 15894.029516596313 26386.866608166136 1.0921381445889093 1.0726666196617698 0.7170833510228771 1.1607362036616835 0.9512095939249399 0.8878032843846445 0.9185291275676211 0.8193883136682318 0.6023462259697584 1.0 14.687532423004404 -7.2835223867006675 1.2993492690233852 0.7903654551105076 0.9952808602894487 0.23111381658240226 0.1444718812014197 0.6543592196782054 2.1470925827222462 0.09170410335820048 0.05200891316437795 5.2056817423480765e-08 7.2835223867006675 0.20491540517894113 ESEITDEDIDGILER ddPTM_PC-9_AZD4547_30min_R2 1 ESEITDEDIDGILER 15 0 O60264 O60264 SMARCA5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 0 124.48 0.00013409 1205100.0 3378.7 3262.2 5041.0 5068.3 4782.0 4186.1 3967.7 5183.9 3728.2 5574.0 False True 4453.056318674227 4316.642354202065 4974.1530462691135 3899.8817394544208 4118.101843328437 3924.34250524885 4320.817613546621 4382.847369171355 3925.2650407288493 5378.855956593558 0.8278816823892712 0.802520533927033 0.9247604112119142 0.7250392594495549 0.7656092441516951 0.729586837222937 0.8032967695017073 0.8148289161375911 0.7297583486906998 1.0 12.393083639365575 -10.998080986040476 3.50543552734087 1.0030048193661663 0.7922202346664463 0.5453266310106526 0.057117802388886245 27955749.668549538 32940297.349473592 776598.7760570536 0.014669647556424414 1.0044284697550301e-11 10.998080986040476 -0.21078458469971995 ESEITDEDIDGILER ddPTM_PC-9_Lapatinib_30min_R1 2 ESEITDEDIDGILER 15 0 O60264 O60264 SMARCA5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 0 ; 185.57 1.9366e-06 2715000.0 13409.300000000001 11641.400000000001 12562.599999999999 14186.5 13680.5 13516.1 10758.6 12651.0 14383.7 10890.8 False True 13218.080923035557 11614.445053545482 11529.751521038355 15229.82253477668 12875.83988689784 12938.047910567979 11315.627665765904 13238.811644746127 12763.656238924164 12773.260268921176 1.0348243631421714 0.9092780393588921 0.9026475056717961 1.1923206929269738 1.008030809348358 1.0129009851970017 0.8858840599449882 1.0364473412444035 0.9992481144363449 1.0 13.640839187556361 ESEKQQDS(ph)QPEEVMDVLEMVENVK ddPTM_PC-9_AZD4547_30min_R2 3 ESEKQQDSQPEEVMDVLEMVENVK 24 1 Q9H307 Q9H307 PNN Pinin 1 ES(0.008)EKQQDS(0.992)QPEEVMDVLEMVENVK;ES(0.019)EKQQDS(0.981)QPEEVMDVLEMVENVK;ES(0.057)EKQQDS(0.943)QPEEVMDVLEMVENVK 70.315 0.00036303 13939300.0 32594.6 28448.100000000002 38922.0 50084.0 47256.0 40320.7 34735.5 41740.0 33847.9 43091.0 True False 42959.00479020302 37643.39199208379 38405.86884881698 38537.90759008643 40695.32009793574 37799.44025498367 37826.892208420155 35290.04208978036 35637.0308921426 41582.39720587959 1.033105536881572 0.9052722911982851 0.9236088207869492 0.9267841726219026 0.978667004127929 0.9090250393173334 0.9096852213963167 0.8486774323051891 0.8570220402565838 1.0 15.343685310842027 -6.942480177690511 5.998001440100489 0.893581323551283 0.9476745095755279 0.16989623360565953 0.05101105123297606 0.3253634896933617 24.00442987775742 0.017818813197705716 0.015609095745080922 1.1416154096731021e-07 6.942480177690511 0.054093186024244955 ESEKQQDS(ph)QPEEVMDVLEMVENVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESEKQQDSQPEEVMDVLEMVENVK 24 1 Q9H307 Q9H307 PNN Pinin 1 ES(0.007)EKQQDS(0.993)QPEEVMDVLEMVENVK;ES(0.014)EKQQDS(0.986)QPEEVMDVLEMVENVK 69.525 0.00040753 8230100.0 40057.2 29706.0 37326.0 54119.0 51859.0 51077.0 49576.0 49251.0 47204.0 38266.6 True False 46838.09279423669 32655.015359885376 38215.99339964329 51086.88788616532 41697.601222946396 48398.43220408039 44879.80238084216 47958.213435747995 47894.26919880566 45204.03166176109 1.0361485706563178 0.7223916575456443 0.8454111722952997 1.1301400783988178 0.9224310241827203 1.0706662752168077 0.9928274255857314 1.060927790569546 1.0595132212359788 1.0 15.46416382915987 -5.741911894969275 24.957923246343448 1.0315154122972423 0.8534244745967124 0.42272151539199154 0.08827224665292865 203.2603499998698 259783.30747298512 0.022574629835729342 0.03902859164954458 1.8117075952475029e-06 5.741911894969275 -0.17809093770052986 ESEKTAESQT(ph)PTPSATSFFSGK ddPTM_PC-9_AZD4547_30min_R2 1 ESEKTAESQTPTPSATSFFSGK 22 1 P55265-5;P55265;P55265-4;A0A3B3ITG9;A0A3B3ISX1;A0A3B3IRQ9;P55265-3;P55265-2 P55265-5 ADAR Double-stranded RNA-specific adenosine deaminase 1 ESEKTAES(0.002)QT(0.992)PT(0.005)PSATSFFSGK 83.755 0.00017955 4205300.0 32761.0 18043.0 35405.0 68455.0 50910.0 41378.0 24224.0 29777.0 21720.0 38079.0 True False 43178.31652886802 23875.04689990431 34935.50656678397 52673.75736920708 43842.025270566875 38790.62711884257 26379.889071893896 25175.64885738833 22868.07485774116 36745.865800345535 1.1750523654408491 0.6497342321344842 0.950732981952366 1.433460777748548 1.1931144991596474 1.0556460236807865 0.717900871222521 0.6851287433034601 0.6223305495641941 1.0 15.165294324060428 -7.250577935249463 7.414756966303818 0.7296563761952162 1.0732255964226096 0.35780716434531756 0.20876774404691803 0.17470542389916477 65.79072682605711 0.08893863137119998 0.06570835608664251 5.6159348993228536e-08 7.250577935249463 0.34356922022739345 ESENSGDSGYPS(ph)EK ddPTM_PC-9_AZD4547_30min_R2 1 ESENSGDSGYPSEK 14 0 O00418 O00418 EEF2K Eukaryotic elongation factor 2 kinase 1 ESENSGDSGYPS(1)EK 117.53 0.00012877 5488700.0 22021.0 40421.0 28831.0 15717.0 18743.0 21453.0 18396.0 17682.0 25084.0 10541.0 True False 29023.219934745648 53486.29777426326 28448.682102159262 12093.688475229394 16140.857977730002 20111.540518645874 20033.20836222588 14949.653191938103 26409.889029999053 10171.962798430695 2.853256594609575 5.258208158460331 2.796774100132204 1.1889237814647904 1.5867987622035122 1.9771543523289952 1.9694535616387185 1.4696920828539108 2.5963414882006357 1.0 13.312310470380856 -5.5133861652212035 5.78541930067109 1.7362836526626648 4.066006362500564 0.6581175373757122 0.6848449605819977 0.08396186990127581 10.363317817782598 0.1708077470140556 0.33048959328455574 3.066294293576e-06 5.5133861652212035 2.329722709837899 ESENSGDSGYPS(ph)EK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESENSGDSGYPSEK 14 0 O00418 O00418 EEF2K Eukaryotic elongation factor 2 kinase 1 ESENSGDS(0.006)GY(0.001)PS(0.993)EK;ES(0.001)ENSGDS(0.002)GYPS(0.997)EK 165.16 0.00049231 4018200.0 39145.0 47284.0 19238.6 28719.0 27089.8 13095.6 21257.9 11697.2 16694.0 14142.3 True False 45771.47535100794 51978.04303093044 19697.321186796806 27109.96753825424 21781.748155756446 12408.84368251376 19244.197818131848 11390.160894207858 16938.11816805487 16706.187039614797 2.7397918652815054 3.1113049858520516 1.1790434968846712 1.6227501508255189 1.3038132581723256 0.7427693496480736 1.1519204096361877 0.6817929709034604 1.013882948149096 1.0 14.02809487496241 -5.266979182390519 23.462317634292088 1.092534272079364 2.92554860003219 0.8837241464502614 0.266754914304202 55.9232540463012 236850.59896361714 0.07585547821260152 0.16584768802611363 5.407802442561136e-06 5.266979182390519 1.8330143279528262 ESENSGDSGYPS(ph)EK ddPTM_PC-9_Lapatinib_30min_R1 1 ESENSGDSGYPSEK 14 0 O00418 O00418 EEF2K Eukaryotic elongation factor 2 kinase 1 ESENSGDS(0.01)GYPS(0.99)EK 130.64 1.8840999999999998e-05 5635100.0 20717.0 38754.0 30438.0 26087.0 25595.0 26929.0 29982.0 33129.0 25206.0 23278.0 True False 20421.571780967486 38664.26749403865 27935.50513407779 28005.525003680905 24089.552421706107 25777.30944456502 31534.3212569473 34668.29428336054 22367.034849052925 27301.571284014703 0.7479998703563442 1.4161920239615255 1.02321968371228 1.0257843664873008 0.8823504028799521 0.9441694463811997 1.1550368632229937 1.269827803048798 0.8192581524474019 1.0 14.7366963643364 -8.297625759812142 24.995683220341192 0.9096291297861302 1.0613499171081375 0.09345547662166986 0.1847068573600523 1666.741728801042 1151284.784345302 0.1740926872779461 0.04495776653890162 5.039346722646652e-09 8.297625759812142 0.15172078732200733 ESEPAPAS(ph)VTALTDAR ddPTM_PC-9_AZD4547_30min_R2 1 ESEPAPASVTALTDAR 16 0 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 1 ES(0.017)EPAPAS(0.936)VT(0.025)ALT(0.022)DAR 115.58 0.00017381 1678000.0 4010.6 3637.9 4893.4 9556.9 6206.0 5859.9 6741.0 5401.9 6212.8 6019.9 True False 5285.887374337717 4813.780031988134 4828.51031870924 7353.704357633117 5344.40402335765 5493.47952664956 7340.93594095264 4567.160478312994 6541.195924317419 5809.1451333149535 0.9099251702326393 0.8286554943138733 0.8311912007531269 1.265884082575291 0.9199983647693611 0.9456605749346702 1.2636860970907744 0.7862018203196056 1.1260169567470808 1.0 12.50411015867588 ESEPAPAS(ph)VTALTDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESEPAPASVTALTDAR 16 0 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 1 ES(0.027)EPAPAS(0.97)VT(0.001)ALT(0.002)DAR 100.58 0.0017569000000000003 2023900.0 5977.0 6433.4 4188.5 6432.7 8184.9 6854.8 6264.5 7057.5 7700.5 5589.0 True False 6988.788048868935 7072.0654351406 4288.369724974708 6072.296674094787 6581.127600796269 6495.322220814268 5671.081208947594 6872.248103039362 7813.105244585271 6602.241457500346 1.0585477816673095 1.0711612837344082 0.6495323978348279 0.9197325958438667 0.9968020168847216 0.9838056155058349 0.8589630121002427 1.0408962088522649 1.1834019241615812 1.0 12.688740186501592 -7.954534266759533 6.533419326058748 1.098655441215079 0.9327511756088201 0.22989332623476633 0.12019987383521376 0.26375496861671804 27.382285846300864 0.06988948224661262 0.03272547471609808 1.110364921720182e-08 7.954534266759533 -0.16590426560625893 ESEPAPAS(ph)VTALTDAR ddPTM_PC-9_Lapatinib_30min_R1 1 ESEPAPASVTALTDAR 16 0 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 1 ES(0.003)EPAPAS(0.95)VT(0.002)ALT(0.044)DAR 136.34 1.0105e-05 1608400.0 5792.5 6756.4 6901.4 5403.9 5179.8 7169.6 7561.4 5929.4 4230.0 3360.0 True False 5709.8978877856 6740.755970911977 6333.993532174397 5801.320832881943 4875.134347878623 6862.9729211539 7952.892293785655 6204.9015703389205 3753.5728561252804 3940.771523081426 1.448928935448872 1.7105168192144125 1.607297833704814 1.472128185788779 1.237101496324909 1.741530276738171 2.0181054007330554 1.5745397910019134 0.9524969499348775 1.0 11.944262392404116 -8.250647895034863 7.512583550114873 0.9739710157356658 1.6078589350795183 0.6219095567953121 0.1949099421677702 0.09131376291898785 38.50300172178267 0.1599273135527083 0.05394468176413563 5.615030310447154e-09 8.250647895034863 0.6338879193438525 ESEPAPASVTALT(ph)DAR ddPTM_PC-9_Lapatinib_30min_R1 1 ESEPAPASVTALTDAR 16 0 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 1 ESEPAPAS(0.314)VT(0.036)ALT(0.65)DAR 87.363 0.010416 1737200.0 7926.9 5726.1 5684.0 6023.5 5353.1 5424.5 4091.0 5396.8 5734.0 3695.3 True False 7813.860952384579 5712.841567260539 5216.683460874503 6466.488283806957 5038.241182599532 5192.5067801271125 4302.811962583268 5647.555029987026 5088.1765383031625 4334.027681322256 1.8029097935988887 1.318136843444808 1.2036571624487087 1.492027453279697 1.1624847723774643 1.1980788222706842 0.9927975266808945 1.3030731331794423 1.1740064698319659 1.0 12.081492652578863 -1.5228787452803376 0.7500960500746787 1.1728741962866092 105.73555695544657 0.6593377046429573 0.13264827221819644 240.2879472097213 1.0371450244216642 0.049661829007382384 42454.8811682534 0.029999999999999995 1.5228787452803376 104.56268275915996 ESEPQAAAEPAEAK ddPTM_PC-9_Lapatinib_30min_R1 1 ESEPQAAAEPAEAK 14 0 P80723;P80723-2 P80723 BASP1 Brain acid soluble protein 1 0 123.28 0.00021026 2920000.0 20477.0 16303.0 16705.0 20113.0 21518.0 16514.0 21650.0 18999.0 22470.0 18868.0 False True 20184.994224978116 16265.251405153333 15331.57938316478 21592.17711500112 20252.353546015707 15807.734716014207 22770.931065736422 19881.762899259473 19939.19198041019 22129.308659970335 0.9121384917681913 0.7350094688938709 0.6928178199664252 0.9757275948732718 0.9151823880811131 0.7143347747057633 1.0289942363597973 0.8984357896016678 0.901030948900729 1.0 14.43367076026759 -7.182632922588163 0.33677107636432063 0.9962436800781477 0.7743811721598839 0.22456596909015214 0.10126792012555785 2.5119390722938832 0.7088491463605363 0.13519922730291048 0.20090768009522472 6.567000924264405e-08 7.182632922588163 -0.22186250791826378 ESEQES(ph)EEEILAQK ddPTM_PC-9_AZD4547_30min_R2 2 ESEQESEEEILAQK 14 0 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 ES(0.029)EQES(0.971)EEEILAQK;ES(0.069)EQES(0.931)EEEILAQK 197.75 1.2462e-47 0.0 38384.0 51945.0 51956.0 33528.0 38033.0 55582.0 51165.0 62371.0 47928.0 41770.0 True False 50589.31356320227 68735.2054101608 51267.02949255267 25798.637602436287 32752.774447367294 52106.44875343198 55718.585880261315 52732.99509299686 50461.37623304871 40307.64501379851 1.2550798625393282 1.7052647304656643 1.2718934453998103 0.6400432869150416 0.812569785115331 1.2927187568411498 1.3823329510118287 1.3082628636563804 1.2519058410823622 1.0 15.29876587531192 ESEQES(ph)EEEILAQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESEQESEEEILAQK 14 0 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 ES(0.422)EQES(0.578)EEEILAQK 130.27 0.00039619 0.0 11922.0 20444.0 16169.0 15467.0 13262.0 12096.0 12605.0 11463.0 15404.0 10169.0 True False 13940.159129766684 22473.545210310946 16554.530281273976 14600.43413469058 10663.406302063579 11461.664466208978 11410.963147702827 11162.108396052445 15629.254358495084 12012.559202240298 1.1604653841928119 1.8708374154043472 1.3781018684333823 1.215430774482065 0.8876881372684425 0.9541401023082092 0.9499194098102529 0.9292031954332223 1.301076156659464 1.0 13.552255920689413 -5.848452737382684 2.5214318287112807 0.9974961000448737 1.5284554770731782 0.5326456018445229 0.19518261400079986 0.19253393259029422 2.4875748100876574 0.05596497632801501 0.09517753849311689 1.417578972778916e-06 5.848452737382684 0.5309593770283045 ESEQES(ph)EEEILAQK ddPTM_PC-9_Lapatinib_30min_R1 2 ESEQESEEEILAQK 14 0 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 ES(0.177)EQES(0.823)EEEILAQK;ES(0.342)EQES(0.658)EEEILAQK 158.15 1.4097e-12 0.0 14796.1 27385.0 21769.0 22364.0 25229.0 20652.8 26069.0 30391.0 24719.0 23521.0 True False 14585.104900727567 27321.591715029383 19979.23685077007 24008.723164116982 23745.079822122418 19769.527888028253 27418.725263403372 31803.076807800113 21934.885917390275 27586.573510237566 0.528703026322386 0.9903945375778602 0.7242377109051126 0.8703046485714212 0.8607477044334795 0.7166358620323632 0.9939155819126321 1.152846213249274 0.7951290474422309 1.0 14.751678652232648 -7.278390140578716 22.68257118466162 0.9982099986653604 0.7963070605170777 0.33288502113947693 0.13986689633424287 286.5264454280228 383410.15967125277 0.05486423212549231 0.03714118204653161 5.267564467034423e-08 7.278390140578716 -0.20190293814828275 ESEQES(ph)EEEILAQKK ddPTM_PC-9_AZD4547_30min_R2 2 ESEQESEEEILAQKK 15 1 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 ESEQES(1)EEEILAQKK;ES(0.244)EQES(0.756)EEEILAQKK 141.74 3.8356e-05 32627000.0 77590.0 62135.0 99043.0 77607.0 63896.0 87562.0 79419.0 95227.0 77109.0 78026.0 True False 102262.00602774216 82218.92363384995 97729.62510645333 59715.905166197575 55025.14332524339 82086.73429793846 86487.13714501078 80511.85524876634 81184.82431885647 75294.33348926608 1.3581633741710533 1.0919669492203026 1.297967862619909 0.793099591946194 0.7308005898357245 1.0902113146355257 1.1486539974132361 1.069295012223517 1.0782328570639401 1.0 16.200253674001146 -5.740116009705336 24.99706279300586 0.9904099951030243 1.2336262233985427 0.42389679488141274 0.13966904473832886 276.8310556573982 324522.35647545167 0.04176871670178192 0.07225704032667989 1.8192148409962064e-06 5.740116009705336 0.24321622829551837 ESEQES(ph)EEEILAQKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESEQESEEEILAQKK 15 1 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 ES(0.068)EQES(0.932)EEEILAQKK;ES(0.08)EQES(0.92)EEEILAQKK 88.78 0.0021734000000000002 13094800.0 32894.0 36170.0 34759.0 37635.0 41898.0 27860.5 38046.0 33903.0 32135.0 26632.0 True False 38462.3045138857 39760.718560797606 35587.78638424158 35526.432964316286 33688.387667309595 26399.446334392796 34442.00745081335 33013.08217319777 32604.91358155281 31460.170781203993 1.2225713833971035 1.2638430616706253 1.1312013094825173 1.1292511160028953 1.070826598545894 0.8391386848467223 1.0947813249440739 1.0493611876042825 1.0363870497814573 1.0 14.94123888197906 -5.820594682639047 1.3465310410821048 1.0124677483459001 1.2421227586761479 0.6299059681078341 0.06844725323154487 0.3019732393946411 1.1025383414019203 0.024490391168810653 0.055485849834454974 1.5114901361673157e-06 5.820594682639047 0.2296550103302477 ESEQES(ph)EEEILAQKK ddPTM_PC-9_Lapatinib_30min_R1 3 ESEQESEEEILAQKK 15 1 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 ES(0.004)EQES(0.996)EEEILAQKK;ES(0.025)EQES(0.975)EEEILAQKK;ESEQES(1)EEEILAQKK 135.43 1.0122e-05 44346200.0 80026.0 86403.0 90748.0 84203.0 88477.0 84868.0 71997.0 81934.0 84590.0 73337.0 True False 78884.81456502891 86202.93916208451 83287.0497374102 90395.56951297354 83272.95681247483 81238.39347697074 75724.65237597343 85740.95275477278 75062.58342781034 86013.20273458993 0.917124488532801 1.0022058988790368 0.968305412302902 1.0509499313949073 0.9681415662363992 0.944487484411518 0.880384056964327 0.9968347884840746 0.8726867625128458 1.0 16.392270505152318 -6.698876299612704 3.87157345636115 0.9345997217516052 0.9870342857056865 0.1560087674644709 0.04963172330854456 0.36641890435030683 11.008042153435184 0.016448469516766397 0.015981199738967573 2.0004315727551597e-07 6.698876299612704 0.052434563954081304 ESEREEEQR ddPTM_PC-9_Lapatinib_30min_R1 1 ESEREEEQR 9 1 P42566;B1AUU8;P42566-2 P42566 EPS15 Epidermal growth factor receptor substrate 15 0 88.177 0.018787 0.0 0.0 779.73 0.0 588.9 403.29 0.0 842.24 1270.8 790.2 692.35 False True 0.0 777.9245830914685 0.0 632.209670512811 379.56927509864653 0.0 885.8470660880292 1329.8460072834857 701.1993548251061 812.0217750016144 0.0 0.9580095103852627 0.0 0.778562459746297 0.4674373111458642 0.0 1.0909154081320886 1.6376974709586352 0.8635228468149293 1.0 9.665374604704432 -7.388627267301905 6.293867710704533 1.2197270983929027 0.402785958402911 0.5282163458811593 0.35963811561053644 0.17943893981577852 8.422357816725617 0.14382254742101236 0.09603644305785193 4.086699763625791e-08 7.388627267301905 -0.8169411399899917 ESES(ph)ESDETPPAAPQLIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESESESDETPPAAPQLIK 18 0 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 ES(0.131)ES(0.868)ES(0.001)DETPPAAPQLIK 121.79 0.00038504 0.0 4204.8 6153.1 6307.3 6040.2 6449.3 4061.8 5529.3 3486.7 4672.7 4625.7 True False 4916.589591414444 6763.939103578762 6457.689952568457 5701.787176592617 5185.605961687423 3848.792057609758 5005.52467533465 3395.177819464023 4741.029397620098 5464.302792978949 0.8997652175739129 1.2378411958191096 1.1817957747264491 1.0434610585487338 0.9489968177368169 0.7043519005855695 0.9160408683366192 0.6213377896675981 0.867636655075524 1.0 12.415821714451454 -6.383248484022871 2.41708754411778 0.8046280328427914 1.1148027020530005 0.47842016964343703 0.13040140075337214 0.22549580183837858 2.5784854586682275 0.04268078093307459 0.05001975240039905 4.137628703354905e-07 6.383248484022871 0.3101746692102091 ESFDGSVR ddPTM_PC-9_Lapatinib_30min_R1 1 ESFDGSVR 8 0 P19338;H7BY16 P19338 NCL Nucleolin 0 93.195 0.034125 3595700.0 23061.0 29802.0 28337.0 26136.0 26327.0 28170.0 30073.0 27484.0 19906.0 24757.0 False True 22732.14591113054 29732.99530002944 26007.24124398324 28058.128627140126 24778.49762087349 26965.234767477334 31630.03279168091 28761.006975274857 17663.976660527158 29036.214463371067 0.7828894479274131 1.0239969586096478 0.8956829161318928 0.966314967212245 0.853365291544163 0.9286759746692788 1.089330457714518 0.990521922599677 0.6083429602302364 1.0 14.825565756749713 -12.158976514814587 2.163938749756853 2.9840106661421344 0.9166250556559478 0.03960198808271331 0.12914890296494727 6697815.382043558 667283.8363685491 66764884.84574059 0.033099797647936094 6.934633051666544e-13 12.158976514814587 -2.0673856104861867 ESGADGAST(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESGADGASTSPR 12 0 O75528;O75528-2 O75528 TADA3 Transcriptional adapter 3 1 ES(0.067)GADGAS(0.091)T(0.721)S(0.121)PR;ESGADGAS(0.253)T(0.513)S(0.234)PR 103.44 0.005122 79108200.0 62000.0 70011.0 66586.0 82291.0 92452.0 80853.0 73695.0 77629.0 72077.0 60960.0 True False 72495.3754441818 76961.22939342014 68173.66276881123 77680.50206102153 74336.69427223514 76612.92634642818 66714.07609440392 75591.32100472448 73130.98976871284 72011.56544090556 1.0067185041779612 1.0687342918072849 0.9467043571599093 1.0787225855375695 1.0322882694896784 1.0638975264230106 0.9264355758124869 1.049710842166826 1.015545063087483 1.0 16.135941009219483 -8.54058788263759 21.81929601526681 0.9999999950439817 1.021927321754209 0.018234957180101374 0.04802691104033011 3406.3446032255033 4196933.362291952 0.04423240983615364 0.011420759064960716 2.880130175577055e-09 8.54058788263759 0.021927326710227346 ESGADGASTS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 ESGADGASTSPR 12 0 O75528;O75528-2 O75528 TADA3 Transcriptional adapter 3 1 ESGADGAS(0.031)T(0.403)S(0.566)PR;ESGADGAS(0.009)T(0.329)S(0.662)PR;ESGADGAS(0.034)T(0.239)S(0.727)PR 129.74 0.00016642 177649000.0 109658.0 116182.0 152014.0 209810.0 176378.0 140894.0 113061.0 164782.0 123244.0 141192.0 True False 144526.9629719057 153735.55943716006 149998.19503581678 161441.54603218674 151890.95920589348 132083.87590705673 123123.20997182131 139318.72821366033 129758.42623238717 136248.91105550033 1.0607568299245589 1.1283433991963183 1.100912982524431 1.1849015510034009 1.114804940672307 0.9694306903726593 0.9036638092591263 1.0225309482063276 0.9523630334155897 1.0 17.05588517389623 -6.757510779857564 6.679783101896445 0.9664399683574687 1.1217817598608293 0.7678895353267645 0.04075197230390526 0.06570310153099138 13.68645246781667 0.013901237112896217 0.013130797464970758 1.747789879044573e-07 6.757510779857564 0.15534179150336058 ESGADGASTS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESGADGASTSPR 12 0 O75528;O75528-2 O75528 TADA3 Transcriptional adapter 3 1 ESGADGAS(0.059)T(0.428)S(0.514)PR;ESGADGAS(0.013)T(0.102)S(0.885)PR 95.477 0.004584 72092000.0 34403.0 43307.0 43848.0 42571.0 54686.0 44288.0 49113.0 43842.0 36271.0 38202.0 True False 40226.74840977715 47606.23275400782 44893.50261446602 40185.88488704417 43970.670866735665 41965.459315431865 44460.66109267192 42691.19395443879 36801.39475700956 45127.72019313441 0.8913977537003326 1.054922175334053 0.9948098956103698 0.8904922454548885 0.9743605632758117 0.9299264207416433 0.9852184179123684 0.9460082133937202 0.8154942150746718 1.0 15.461726276443791 -5.728525365791901 24.95291211513018 0.9358338851290603 0.9878312184752376 0.09906529029423217 0.06210125649574975 394.8838164281609 299368.2014012036 0.016334709982398596 0.02828989009549737 1.8684205454275471e-06 5.728525365791901 0.05199733334617729 ESGADGASTS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 ESGADGASTSPR 12 0 O75528;O75528-2 O75528 TADA3 Transcriptional adapter 3 1 ESGADGAS(0.015)T(0.143)S(0.842)PR;ESGADGAS(0.008)T(0.082)S(0.911)PR;ESGADGAS(0.044)T(0.305)S(0.652)PR 129.34 0.00017816 161472000.0 128435.0 126669.0 144488.0 107146.0 134578.0 123226.0 120749.0 117628.0 134232.0 99226.6 True False 126603.4933479056 126375.70571301992 132608.75437980928 115025.87426857802 126662.38663052794 117955.91123383585 127000.79239060551 123093.42630212575 119113.37863437571 116377.78559886657 1.0878664918430845 1.0859091798551177 1.1394679293597145 0.9883834245227148 1.0883725444571575 1.0135603683026657 1.091280365381367 1.0577055205914194 1.023506144419505 1.0 16.82845617473709 -1.5228788160687987 0.0670681812220806 0.9298427986939112 1.3527823510403618 0.29791014558587414 0.039043034265670476 357.8778123543945 1.7856109095213815 2.056446521761169 14.414481387136906 0.029999995110106738 1.5228788160687987 0.42293955234645064 ESGAPS(ph)PITFTSLR ddPTM_PC-9_AZD4547_30min_R2 4 ESGAPSPITFTSLR 14 0 Q8NEV8-2;Q8NEV8;E9PPH6 Q8NEV8-2 EXPH5 Exophilin-5 1 ES(0.006)GAPS(0.984)PIT(0.001)FT(0.002)S(0.006)LR;ES(0.001)GAPS(0.999)PITFTSLR;ESGAPS(0.96)PIT(0.04)FTSLR;ESGAPS(0.884)PIT(0.081)FT(0.006)S(0.029)LR 182.7 1.3937e-05 19787500.0 79874.2 65502.2 94775.0 138222.0 105914.0 95593.0 93979.0 164606.0 115197.0 100811.0 True False 105272.53411343072 86674.50518466509 93518.2215751151 106357.0534086121 91209.66930871751 89615.55459837413 102342.94893855345 139169.924969583 121286.07824066354 97281.63757448045 1.0821418793740216 0.8909647015173406 0.9613142203071569 1.0932901219634934 0.9375836137512165 0.9211970196303795 1.0520274071270437 1.4305878112200996 1.246752020881689 1.0 16.56987989390555 -7.577178060789346 8.211682946418534 1.2531310152117194 0.9797733469517017 0.47024832341108946 0.11508452997809071 0.1969689186807705 26.474523732974383 0.051795083432873285 0.029825685144580432 2.6474144758103308e-08 7.577178060789346 -0.2733576682600177 ESGAPS(ph)PITFTSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ESGAPSPITFTSLR 14 0 Q8NEV8-2;Q8NEV8;E9PPH6 Q8NEV8-2 EXPH5 Exophilin-5 1 ES(0.177)GAPS(0.797)PIT(0.026)FTSLR;ES(0.097)GAPS(0.903)PITFTSLR;ESGAPS(0.992)PIT(0.006)FT(0.001)S(0.001)LR 166.3 0.00011904 10909400.0 58535.0 56140.0 57643.0 65170.0 76903.0 74942.0 64579.0 79000.0 57969.0 47555.0 True False 68443.81938105127 61713.20818366543 59017.42773229488 61518.73618399071 61834.409202804694 71011.90959214895 58461.60960852848 76926.33370741883 58816.68695842649 56176.34505482713 1.2183743765147288 1.0985621817053854 1.050574359629394 1.095100368739716 1.1007196915793542 1.2640891735274442 1.0406801929080822 1.369372351162043 1.0470009556695516 1.0 15.777675142447244 ESGAPS(ph)PITFTSLR ddPTM_PC-9_Lapatinib_30min_R1 3 ESGAPSPITFTSLR 14 0 Q8NEV8-2;Q8NEV8;E9PPH6 Q8NEV8-2 EXPH5 Exophilin-5 1 ESGAPS(0.99)PIT(0.008)FT(0.002)SLR;ES(0.002)GAPS(0.996)PIT(0.002)FTSLR;ES(0.022)GAPS(0.978)PITFTSLR 131.72 1.5490999999999998e-05 10020900.0 42349.0 37523.0 43678.0 38412.0 41872.0 39197.0 38637.0 31507.3 44206.0 37592.0 True False 41745.09549414457 37436.117798906256 40086.96344195574 41236.94661867564 39409.17128351938 37520.63568266979 40637.43480770709 32971.24418105362 39227.054770183044 44089.72711180863 0.9468213624521142 0.8490893514484846 0.9092132355525326 0.9352960274419815 0.893840217780898 0.8510063032941878 0.9216984878280885 0.7478214618439513 0.88970962942696 1.0 15.42815492713911 -6.563568823575367 7.529920235258008 0.8690183945439851 0.9067826448822418 0.020388314488069437 0.06412815606665821 0.6260663796888577 95.57675909238525 0.0203764704198739 0.020460926310090968 2.731688513054766e-07 6.563568823575367 0.0377642503382567 ESGS(ph)PYSVLVDTK ddPTM_PC-9_AZD4547_30min_R2 2 ESGSPYSVLVDTK 13 0 Q9Y2D9;D6RF85 Q9Y2D9 ZNF652 Zinc finger protein 652 1 ESGS(0.995)PYS(0.005)VLVDTK;ES(0.011)GS(0.691)PYS(0.298)VLVDTK 138.31 6.3485e-05 6095000.0 35786.0 34844.0 38189.0 54860.0 50966.0 45056.0 33293.0 48168.0 34913.0 41146.0 True False 47165.20360495927 46106.64158844237 37682.58890775066 42212.874578550895 43890.250637197205 42238.641197413344 36256.01250291294 40724.74239052563 36758.429903697834 39705.491063867674 1.1878760932358798 1.161215750090541 0.9490523325133265 1.063149540466582 1.1053949834444359 1.0637984839293642 0.9131233875081377 1.0256702863847837 0.9257769874844417 1.0 15.277050917970701 -1.5228787452804156 0.3785896612113794 0.9816952681812107 3.9909902786787947 0.5055317500451275 0.0633484106328837 59.96619363561405 0.8200744472809172 0.05113153155222528 132.22684462126205 0.02999999999999461 1.5228787452804156 3.009295010497584 ESGVAGDPWKEET(ph)DTDLEVVLEK ddPTM_PC-9_AZD4547_30min_R2 1 ESGVAGDPWKEETDTDLEVVLEK 23 1 Q1ED39 Q1ED39 KNOP1 Lysine-rich nucleolar protein 1 1 ESGVAGDPWKEET(0.5)DT(0.5)DLEVVLEK 57.39 0.0055927 1710400.0 5871.8 6994.0 6016.8 9123.4 7499.4 7423.1 7766.9 7136.4 8594.2 6935.0 True False 7738.910258972778 9254.67372487561 5937.01330069272 7020.141085124885 6458.2377590667675 6958.932383534252 8458.139053520994 6033.6333581578465 9048.47186659296 6692.207760849714 1.156406157060217 1.38290293063175 0.8871531657198422 1.0490022629293765 0.96503844319483 1.0398559985308453 1.2638787311718276 0.9015908611587624 1.352090698607371 1.0 12.70826651947273 -5.251959718109677 24.971121504482344 1.0569713117594715 1.269654534441927 0.24641728212135972 0.14852328890080127 878.3795812727864 2313797.419653694 0.03579100575906096 0.09208058641271487 5.598095228088241e-06 5.251959718109677 0.21268322268245554 ESGVVAVS(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESGVVAVSPEK 11 0 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 ES(0.167)GVVAVS(0.833)PEK 64.827 0.046218 2631300.0 19172.0 35420.0 20475.0 19735.0 20930.0 15273.0 22910.0 16670.0 16655.0 16889.0 True False 22417.440935739538 38936.26351737492 20963.201651869917 18629.311931733264 16828.916747262156 14472.056993420116 20739.79894596365 16232.430163324992 16898.54786683562 19950.842006749557 1.123633825988673 1.9516100375213445 1.0507427027279284 0.9337606866632894 0.8435191227301974 0.7253857751228787 1.0395450447127585 0.8136213077038758 0.8470092571089822 1.0 14.284162014885679 -5.454515211915322 6.399172807890688 0.8841357257417654 1.5372981583728966 0.6129250469949353 0.2041386841643207 0.1323521938182715 9.936509745116023 0.04965060497284011 0.10371545036379969 3.5114362488813456e-06 5.454515211915322 0.6531624326311313 ESGVVAVS(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 1 ESGVVAVSPEK 11 0 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 ESGVVAVS(1)PEK 107.39 0.0023159 2284100.0 30074.0 34354.0 17082.0 20206.0 30534.0 28611.0 24552.0 27838.0 27962.0 25380.0 True False 29645.139245103852 34274.45542370347 15677.583898426865 21692.016645240034 28738.0501521537 27387.37422549853 25823.182426141375 29131.45510761542 24812.625107086333 29766.899183275742 0.9959095525058821 1.1514284780781014 0.5266784357315649 0.7287294693236807 0.9654364727482233 0.9200613761236466 0.8675133498839507 0.97865266140931 0.8335643210370759 1.0 14.86142132346646 ESHS(ph)PFGLDSFNSTAK ddPTM_PC-9_AZD4547_30min_R2 1 ESHSPFGLDSFNSTAK 16 0 Q7LBC6;Q7LBC6-2;Q7LBC6-3 Q7LBC6 KDM3B Lysine-specific demethylase 3B 1 ES(0.185)HS(0.815)PFGLDSFNSTAK 136.33 4.3171999999999995e-07 0.0 17742.0 19258.0 23881.0 24775.0 25955.0 25120.0 21710.0 26603.0 24106.0 21992.0 True False 23383.58694347475 25482.771889284322 23564.322336431782 19063.506519934348 22351.596265911663 23549.24242895561 23642.147942157197 22492.117626124273 25380.193946625623 21222.066773843842 1.1018524817900854 1.2007676802097236 1.1103688715876987 0.8982869917000772 1.0532242926245037 1.1096582948264024 1.114036073588087 1.0598457664757595 1.1959341291823031 1.0 14.37327754377472 -8.773662464389448 0.005922030723202423 1.5020055040937223e-07 2.142047236084518 0.040020778568057525 0.08302938733373826 28273.549300264385 86.7701152070652 15867.39146147159 15511.180509220014 1.6839823512028392e-09 8.773662464389448 2.1420470858839677 ESHS(ph)PFGLDSFNSTAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESHSPFGLDSFNSTAK 16 0 Q7LBC6;Q7LBC6-2;Q7LBC6-3 Q7LBC6 KDM3B Lysine-specific demethylase 3B 1 ES(0.308)HS(0.692)PFGLDSFNSTAK 132.23 4.1669e-06 3181900.0 15284.0 22518.0 22880.0 25386.0 22772.0 20931.0 23236.0 17691.0 18858.0 16281.0 True False 17871.27932723989 24753.438223722456 23425.545972883214 23963.704722522452 18309.990070169795 19833.34151308037 21034.917865928055 17226.629995163905 19133.762574169083 19232.616419674923 0.92921727014519 1.287055161064812 1.2180113959387726 1.245992963183503 0.9520280377161121 1.031234704644289 1.0937106739366664 0.8956987244616963 0.9948600937413428 1.0 14.231267420902352 -6.265200436151079 24.98200531919155 0.9961620371472507 1.1818497823731606 0.4156076449964541 0.1015462063180335 307.88208116447737 2045038.5510427833 0.03080357980942914 0.03627089072245377 5.429996677444876e-07 6.265200436151079 0.18568774522590992 ESHS(ph)PFGLDSFNSTAK ddPTM_PC-9_Lapatinib_30min_R1 1 ESHSPFGLDSFNSTAK 16 0 Q7LBC6;Q7LBC6-2;Q7LBC6-3 Q7LBC6 KDM3B Lysine-specific demethylase 3B 1 ES(0.045)HS(0.955)PFGLDSFNSTAK 82.663 0.014319 0.0 27769.0 23344.0 31073.0 27738.0 31676.0 30243.0 26885.0 30066.0 27137.0 23185.0 True False 27373.00896778908 23289.948402251088 28518.29788524867 29777.945051255476 29812.879957412108 28949.577389876333 28276.973750684712 31462.97612132931 24080.54529472147 27192.49635792942 1.006638324318724 0.8564843806795128 1.0487561535310326 1.0950794902863756 1.0963642162525684 1.064616393023237 1.0398814944564314 1.1570462567021584 0.8855584635464888 1.0 14.730920980999882 -5.359796946359734 7.765608954065062 1.0581670078000078 0.9320630669782366 0.2688888018073764 0.07580544446190543 0.29115387109554475 20.207289005896563 0.018585096465735928 0.0388997181896184 4.367199721878953e-06 5.359796946359734 -0.12610394082177123 ESHT(ph)PVSIQEEIVGDFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESHTPVSIQEEIVGDFK 17 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;A0A0A0MR81;F5H176 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 ES(0.288)HT(0.712)PVSIQEEIVGDFK 113.05 0.00046046 1651000.0 8907.8 8344.2 7729.9 11332.0 11862.0 7233.6 8360.6 7669.6 8653.6 7304.9 True False 10415.71460293035 9172.55703110333 7914.2101318089935 10697.10477883969 9537.726252079481 6854.257281974977 7568.623442497762 7468.281126612921 8780.14252899722 8629.220544443415 1.2070284389286243 1.0629647236226665 0.9171407882146626 1.2396374300258024 1.1052824763206541 0.7943078110790222 0.8770923635010581 0.8654641619308184 1.017489642752379 1.0 13.075014534975713 -6.741980967364018 24.931101489740193 0.900351163808436 1.1008836583692416 0.48096846087517475 0.10118921092360358 207.27687451605536 265573.035637101 0.03385748952034188 0.033809721993980635 1.811419475005245e-07 6.741980967364018 0.20053249456080557 ESHT(ph)PVSIQEEIVGDFK ddPTM_PC-9_Lapatinib_30min_R1 1 ESHTPVSIQEEIVGDFK 17 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;A0A0A0MR81;F5H176 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 ES(0.14)HT(0.86)PVSIQEEIVGDFK 126.26 7.7091e-05 1953700.0 13967.0 16497.0 15211.0 14942.0 15719.0 19071.0 19859.0 15690.0 15483.0 11377.0 True False 13767.828018765897 16458.802210072663 13960.410296157992 16040.884525050793 14794.439324743056 18255.377786672343 20887.201849166722 16419.014679161064 13739.141496781971 13343.499291100406 1.0318004084542127 1.2334697106815182 1.0462330751176374 1.202149764098945 1.1087375958876373 1.3681102226945796 1.5653466450961384 1.230487919320527 1.029650558451743 1.0 13.703849437968081 -6.741728979101653 24.738511648365986 1.27353880299294 1.1305013056995408 0.09107645905567718 0.16226724599027872 431.0187360753877 540969.7611159496 0.054932623503915985 0.054855412212419755 1.8124708097887826e-07 6.741728979101653 -0.1430374972933992 ESIESEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESIESEIR 8 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 101.33 0.021286000000000003 1573000.0 8086.4 10792.0 11558.0 10083.0 11673.0 11279.0 9872.7 8275.5 9214.5 6676.7 False True 9455.267806319855 11863.358438156709 11833.5865539591 9518.082199527062 9385.759445331632 10687.50938445528 8937.486383841795 8058.276893617032 9349.244630378671 7887.13285727188 1.1988219264751152 1.5041408142654498 1.5003660732110804 1.2067860871332297 1.1900090457685177 1.3550563402265339 1.1331730485053888 1.0216991445994672 1.1853793767095901 1.0 12.94528522947093 -7.039018958870975 0.5599498124340141 1.0282615588886848 1.4044376440683637 0.5118623526209946 0.1157881376706266 0.7227130648617267 0.48049600243269963 0.10702435049689983 0.10071982427473108 9.140733372636538e-08 7.039018958870975 0.37617608517967893 ESIESEIRR ddPTM_PC-9_AZD4547_30min_R2 2 ESIESEIRR 9 1 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 ; 161.79 8.214799999999999e-05 26972000.0 52152.0 56543.0 85922.0 115767.0 91639.0 77673.0 66814.0 86972.0 72212.0 81829.0 False True 68735.25117101197 74819.41899137007 84782.6181395626 89078.70673232053 78916.50665428142 72816.09503122105 72760.3165641312 73532.475817738 76028.97889628023 78964.19161680914 0.870461024974012 0.9475107318827187 1.0736843676053651 1.128089896298746 0.99939611915792 0.9221407012507256 0.9214343245254305 0.9312129246452655 0.9628285598772077 1.0 16.268910953237885 -6.673351991856868 6.190455088237637 0.9417997191467485 1.0124375653282183 0.13943051234957715 0.06804539171071225 0.3963399091099539 22.53843985106996 0.02496072757000826 0.0248399026894166 2.121524288230073e-07 6.673351991856868 0.07063784618146973 ESIESEIRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ESIESEIRR 9 1 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 ;; 161.79 9.9873e-05 25659800.0 65672.0 53148.0 65137.0 79595.0 74571.0 78444.0 84718.0 81299.0 70024.0 60812.0 False True 76788.97251887586 58424.18219710456 66690.11311344811 75135.55020047154 59959.34786240252 74330.2585472303 76692.89773479474 79164.987393411 71047.96852760708 71836.73421247296 1.0689374087045154 0.8132911780803144 0.9283566944482389 1.0459210183224867 0.8346613820870468 1.0347109923925857 1.0676000040307874 1.102012615986455 0.9890200230632293 1.0 16.132434144403504 -6.9645303205894935 23.95697628187562 1.0485872814059212 0.9365220691524505 0.2793225037189023 0.08015909794633592 133.83640992773894 90395.22190904609 0.027199218560902988 0.023987319901690483 1.0850997899462378e-07 6.9645303205894935 -0.11206521225347066 ESIESEIRR ddPTM_PC-9_Lapatinib_30min_R1 2 ESIESEIRR 9 1 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 ; 169.09 4.1176999999999996e-05 32757000.0 100999.0 70340.0 84470.0 74470.0 80702.0 79643.0 58522.0 57164.0 85520.0 60170.0 False True 99558.73573905189 70177.13205167657 77525.20266362945 79946.7722246374 75955.26702623662 76236.8545469009 61551.98280965479 59820.04812744189 75887.83703447608 70570.30432851473 1.4107737905676574 0.9944286441644365 1.0985527609848285 1.1328670463496076 1.076306355044951 1.0802965251787433 0.8722079831641596 0.8476660076307894 1.0753508541100727 1.0 16.10677361105521 -7.080206753033362 3.7322189628543057 0.9368445180655393 1.12865964471168 0.3733506503913483 0.11714504936538582 0.26189458651357034 6.892705095905564 0.045425836280645 0.03527004094286402 8.313678905150117e-08 7.080206753033362 0.19181512664614064 ESIPSLPQS(ph)PMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESIPSLPQSPMR 12 0 Q8NEZ4;Q8NEZ4-3;H0Y765;H7BY37;Q8NEZ4-2 Q8NEZ4 KMT2C Histone-lysine N-methyltransferase 2C 1 ES(0.002)IPS(0.004)LPQS(0.994)PMR 82.705 0.010409999999999999 5145800.0 24820.0 46386.0 34784.0 32206.0 32769.0 26723.0 39600.0 24671.0 26241.0 31905.0 True False 29021.535782654675 50990.89552560573 35613.382479054584 30401.60223326078 26348.149684234762 25321.59883684713 35848.80132082762 24023.412391085225 26624.724981905325 37689.12394015895 0.7700241541494499 1.3529339553385937 0.9449246561315638 0.8066412549554359 0.699091592738243 0.6718542696044513 0.9511709897461849 0.6374096789627822 0.7064299245633524 1.0 15.201860640407988 -5.650868563481054 3.545822045400204 0.7644958605415944 1.0780331523438829 0.2974177731454589 0.17241656465796865 0.23319139506328362 5.629924860400188 0.04555983633783322 0.08381930206095975 2.2342483018472213e-06 5.650868563481054 0.3135372918022885 ESKEEET(ph)SIDVAGKPNEVTK ddPTM_PC-9_Lapatinib_30min_R1 1 ESKEEETSIDVAGKPNEVTK 20 2 P53985 P53985 SLC16A1 Monocarboxylate transporter 1 1 ES(0.066)KEEET(0.467)S(0.467)IDVAGKPNEVTK 88.79 0.001389 0.0 15320.0 18266.0 6558.5 6540.7 10342.0 6295.2 6115.1 5557.4 9398.1 4462.9 True False 15101.533990656075 18223.706199259705 6019.28544654212 7021.724897135574 9733.703893154312 6025.968970827941 6431.7099565859 5815.617092286152 8339.587011619624 5234.306318559551 2.885107036458639 3.4815895536420873 1.1499681295302164 1.3414814628326737 1.8595976812898805 1.151244998685184 1.2287607115733088 1.1110578438379537 1.593255439034876 1.0 12.35378263994898 -5.263809937483096 24.999343604456758 1.321365730330852 3.1833483946068477 0.8818735294980671 0.2750123108931585 56.50945959022514 595942.4804879262 0.07015695651950413 0.15806504705447952 5.447409984756422e-06 5.263809937483096 1.8619826642759958 ESLCDS(ph)PHQNLSR ddPTM_PC-9_AZD4547_30min_R2 2 ESLCDSPHQNLSR 13 0 O15042-2;O15042;E7ET15;C9J5L1;E7EW00;U3KPT1;C9JDJ7;H0Y8D9 O15042-2;H0Y8D9 U2SURP U2 snRNP-associated SURP motif-containing protein 1 ES(0.027)LCDS(0.958)PHQNLS(0.016)R;ES(0.014)LCDS(0.986)PHQNLSR 119.96 0.00012463 17523000.0 26037.0 32979.0 43478.0 44373.0 45443.0 38058.0 34276.0 47880.0 34412.0 41089.0 True False 34316.2243967564 43638.81681050512 42901.45331197945 34143.49040601601 39134.02385327775 35678.227243678026 37326.49759858962 40481.246172944026 36230.94806650962 39650.48661651826 0.8654679254922529 1.100587168893038 1.081990587578485 0.8611115100865356 0.9869746172793412 0.8998181431855263 0.9413881337597387 1.020952064585247 0.9137579676365416 1.0 15.275050951277688 -5.748297298360532 24.997751459764306 0.9467141657674834 1.024472394530327 0.15378278451469518 0.07416018407590433 390.61514907510497 742988.9671341098 0.019564322488744186 0.033628564531347264 1.785265044747695e-06 5.748297298360532 0.07775822876284355 ESLCDS(ph)PHQNLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESLCDSPHQNLSR 13 0 O15042-2;O15042;E7ET15;C9J5L1;E7EW00;U3KPT1;C9JDJ7;H0Y8D9 O15042-2;H0Y8D9 U2SURP U2 snRNP-associated SURP motif-containing protein 1 ES(0.201)LCDS(0.799)PHQNLSR 64.58800000000001 0.023637000000000002 7917900.0 23371.0 32540.0 34320.0 24215.0 38122.0 20433.0 24655.0 22218.0 22931.0 17150.0 True False 27327.2487017092 35770.356150631844 35138.31895932482 22858.312056089228 30652.26776106678 19361.45750975928 22319.499913257696 21634.801041916893 23266.322493810098 20259.15924067469 1.3488836519357514 1.7656387279297867 1.734441125709549 1.1282951964855565 1.5130078892674705 0.9556890925111503 1.1016992190103536 1.0679022157286913 1.148434750791527 1.0 14.306286682786334 -6.236236886927213 1.1638036049100047 1.066969524304058 1.6169654849215476 0.5799810326511718 0.1835301676817649 0.3302176030672256 0.9217849990202563 0.07449928098596385 0.1128224007302574 5.804477246080538e-07 6.236236886927213 0.5499959606174896 ESLCDS(ph)PHQNLSR ddPTM_PC-9_Lapatinib_30min_R1 2 ESLCDSPHQNLSR 13 0 O15042-2;O15042;E7ET15;C9J5L1;E7EW00;U3KPT1;C9JDJ7;H0Y8D9 O15042-2;H0Y8D9 U2SURP U2 snRNP-associated SURP motif-containing protein 1 ESLCDS(1)PHQNLSR;ES(0.217)LCDS(0.783)PHQNLSR 147.53 6.2529e-05 16461000.0 15927.4 36738.0 46311.0 35299.0 47747.0 45952.0 41725.0 36336.0 41805.0 38148.0 True False 15700.272355272566 36652.93541817598 42503.488345629674 37895.00621401207 44938.615334213755 43986.7400793439 43885.31633800705 38024.30321108966 37096.48067383389 44741.830970985175 0.3509081326031137 0.8192095545205828 0.9499720378719625 0.846970394184064 1.00439821882471 0.9831233797264366 0.9808565135938766 0.8498602400904918 0.8291229900244974 1.0 15.449336676597126 -4.745594867826925 2.785416846874798 0.9280800815649607 0.21166513892914196 0.8823236098704654 0.06328645418629206 0.16430235994850853 1.6048673132417033 0.017119151258071404 0.28448591296118286 1.7964086275756517e-05 4.745594867826925 -0.7164149426358187 down ESLCDS(ph)PHQNLSRPLLENK ddPTM_PC-9_AZD4547_30min_R2 2 ESLCDSPHQNLSRPLLENK 19 1 O15042-2;O15042;E7ET15;C9J5L1;E7EW00;U3KPT1;C9JDJ7;H0Y8D9 O15042-2;H0Y8D9 U2SURP U2 snRNP-associated SURP motif-containing protein 1 ES(0.097)LCDS(0.829)PHQNLS(0.075)RPLLENK;ES(0.087)LCDS(0.901)PHQNLS(0.012)RPLLENK 50.776 0.023887000000000002 44593000.0 74114.0 68908.0 131465.0 176950.0 170308.0 138534.0 104532.0 144818.0 99677.0 153365.0 True False 97680.71033303371 91181.16343061608 129721.68820229509 136156.91135024748 146663.67393006713 129871.44708013305 113835.14549468343 122439.70568657904 104945.72272537141 147995.73803067318 0.660023806312508 0.6161066841784196 0.8765231345743845 0.9200056242297192 0.9909993076940502 0.8775350480242631 0.7691785385812278 0.8273191330766737 0.7091131415123634 1.0 17.17519610427383 -5.2634385940448665 24.972356669200845 0.8677521278783927 0.6380652300616599 0.5434173180510058 0.08547789150260114 129.11825237996692 1612850.8317416636 0.02350228871195903 0.053213325238413475 5.45206978382622e-06 5.2634385940448665 -0.2296868978167328 ESLCDS(ph)PHQNLSRPLLENK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESLCDSPHQNLSRPLLENK 19 1 O15042-2;O15042;E7ET15;C9J5L1;E7EW00;U3KPT1;C9JDJ7;H0Y8D9 O15042-2;H0Y8D9 U2SURP U2 snRNP-associated SURP motif-containing protein 1 ES(0.493)LCDS(0.507)PHQNLSRPLLENK;ES(0.005)LCDS(0.971)PHQNLS(0.024)RPLLENK 73.796 0.0021873 16286700.0 17084.1 18560.9 22161.4 22342.8 22805.0 15374.9 25111.2 22095.6 19737.2 18736.2 True False 19976.100703644264 20403.503487285285 22689.81182357753 21091.005352334938 18336.523957062273 14568.613178035428 22732.485346655725 21515.613912223384 20025.819210886104 22132.924744322416 0.9025513317560335 0.9218620549694515 1.0251610252909737 0.95292445964446 0.8284727015920477 0.6582326261138443 1.027089081504563 0.9721089354782455 0.9047976913228862 1.0 14.433906487503771 -10.176956292227315 7.419651176520019 1.0000122760818455 0.9107485472826766 0.06564197053936571 0.1014539118569589 0.0 0.0 0.10512629759664333 0.025496872295357444 6.653401132374472e-11 10.176956292227315 -0.08926372879916888 ESLCDS(ph)PHQNLSRPLLENK ddPTM_PC-9_Lapatinib_30min_R1 1 ESLCDSPHQNLSRPLLENK 19 1 O15042-2;O15042;E7ET15;C9J5L1;E7EW00;U3KPT1;C9JDJ7;H0Y8D9 O15042-2;H0Y8D9 U2SURP U2 snRNP-associated SURP motif-containing protein 1 ES(0.006)LCDS(0.992)PHQNLS(0.003)RPLLENK 80.738 0.0011239000000000002 23060000.0 31430.0 34326.0 35772.0 26289.0 31555.0 35662.0 27609.0 22690.0 28862.0 24362.0 True False 30981.802436443908 34246.52025598317 32830.96424391322 28222.380757533178 29698.996939516936 34136.819392182326 29038.458928125503 23744.26023391744 25611.25762966617 28572.939239675496 1.0843057543559795 1.198564836774983 1.149022995797547 0.9877311018232404 1.0394099357576008 1.1947255095401945 1.0162923276651776 0.8310051701277865 0.8963466241548987 1.0 14.802361830538272 -7.545891597799225 5.68394177718925 0.9002331318977668 1.1064542031945257 0.6061791360844524 0.07213859238717343 0.11705010050874126 11.728293135674575 0.0354505016817627 0.020718957368707186 2.8451711886082678e-08 7.545891597799225 0.20622107129675893 ESLCDSPHQNLS(ph)RPLLENK ddPTM_PC-9_Lapatinib_30min_R1 1 ESLCDSPHQNLSRPLLENK 19 1 O15042-2;O15042;E7ET15;C9J5L1;E7EW00;U3KPT1;C9JDJ7;H0Y8D9 O15042-2;H0Y8D9 U2SURP U2 snRNP-associated SURP motif-containing protein 1 ES(0.001)LCDS(0.011)PHQNLS(0.989)RPLLENK 57.498999999999995 0.012411 8934000.0 24184.0 17660.0 25974.0 19811.0 21130.0 21698.0 17904.0 16747.0 22379.0 13267.0 True False 23839.131725197567 17619.109355027176 23838.517982539463 21267.967027558658 19887.174943178354 20770.02712050845 18830.98151505518 17525.126757929273 19858.441358682667 15560.183272833712 1.532059829064992 1.1323201691196088 1.5320203859140122 1.3668198281886614 1.2780810222138623 1.3348189257365963 1.2102030666908599 1.1262802275938566 1.2762344125697553 1.0 13.925571432498952 -8.15126179505637 0.2952582459905483 0.9652072561894621 1.4328603784570342 0.49801803589022686 0.1156207092633164 1.405902095000157 0.44328405372329804 0.24717228152686752 0.19745736836649902 7.058919105342775e-09 8.15126179505637 0.46765312226757205 ESLPPAAEPS(ph)PVSK ddPTM_PC-9_AZD4547_30min_R2 4 ESLPPAAEPSPVSK 14 0 Q9NWT1 Q9NWT1 PAK1IP1 p21-activated protein kinase-interacting protein 1 1 ESLPPAAEPS(0.995)PVS(0.005)K;ESLPPAAEPS(0.973)PVS(0.027)K;ESLPPAAEPS(0.997)PVS(0.003)K;ESLPPAAEPS(0.988)PVS(0.012)K 193.47 1.6324999999999998e-07 126881000.0 443168.0 450487.0 496660.0 476360.0 477230.0 533650.0 501427.0 565800.0 474318.0 507780.0 True False 584086.2055329633 596098.1129965737 490073.96388812043 366542.5616886349 410974.85208942526 500280.78113901895 546053.0316071874 478368.61079055513 499389.4811406116 490002.776756204 1.1920059094350184 1.2165198673826216 1.0001452790377794 0.7480418052222682 0.8387194350408788 1.0209754002841676 1.1143876269886335 0.9762569387000896 1.019156431003406 1.0 18.902430399177014 -5.310808367948135 4.9298366773274065 0.9571660122364809 1.205572217722694 0.49679105659442335 0.0967724713230947 0.1706426693011498 9.47092672611129 0.028979194487412572 0.06503734735472906 4.888680243370149e-06 5.310808367948135 0.24840620548621306 ESLPPAAEPS(ph)PVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ESLPPAAEPSPVSK 14 0 Q9NWT1 Q9NWT1 PAK1IP1 p21-activated protein kinase-interacting protein 1 1 ES(0.003)LPPAAEPS(0.919)PVS(0.078)K;ESLPPAAEPS(0.946)PVS(0.054)K;ESLPPAAEPS(0.878)PVS(0.122)K;ESLPPAAEPS(0.731)PVS(0.269)K 172.26 1.3907000000000001e-05 112716000.0 728960.0 776010.0 791970.0 753320.0 890910.0 660890.0 884310.0 714890.0 661290.0 598660.0 True False 852358.5303837204 853047.1443285766 810853.5683629523 711113.922696391 716342.5809509454 626231.7649696477 800541.7549500265 696124.8949885669 670960.1152122321 707192.3190100469 1.2052711935232587 1.2062449229124865 1.1465814129571064 1.0055453143097393 1.0129388593384432 0.885518335162731 1.132000070462662 0.9843501919860037 0.9487661236924435 1.0 19.431743079785086 -5.669556365481834 2.6863029460664416 0.9946016555179561 1.2042319348056119 0.7005185560554086 0.05790548135001481 0.1489513001884852 2.1657832231828253 0.016731284199231547 0.03241611130805196 2.1401471469273357e-06 5.669556365481834 0.20963027928765576 ESLPPAAEPS(ph)PVSK ddPTM_PC-9_Lapatinib_30min_R1 4 ESLPPAAEPSPVSK 14 0 Q9NWT1 Q9NWT1 PAK1IP1 p21-activated protein kinase-interacting protein 1 1 ESLPPAAEPS(1)PVSK;ESLPPAAEPS(0.703)PVS(0.297)K;ES(0.019)LPPAAEPS(0.928)PVS(0.052)K;ESLPPAAEPS(0.993)PVS(0.007)K 190.82 1.8399000000000002e-06 135218000.0 355536.0 479660.0 490110.0 436614.0 562310.0 490510.0 482697.0 439935.0 498610.0 430868.0 True False 350465.99144268193 478549.37674022344 449815.0476793103 468724.0500616072 529236.0313439948 469532.0307346571 507688.6888054403 460375.986161678 442451.29120393033 505342.95970447833 0.6935210725951984 0.9469794078462602 0.8901183622749184 0.9275365196256308 1.047280903356186 0.9291353955128547 1.0046418557059422 0.9110169189472892 0.8755465624032307 1.0 18.94690330453742 -4.761435896231468 13.931670334754548 0.9470855718765112 0.6934007751732498 0.6872944191667842 0.05149774947397451 0.030458188488496032 787.5067772319252 0.013005487973386319 0.07255187088923261 1.7320646722179753e-05 4.761435896231468 -0.2536847967032614 ESLPPAAEPS(ph)PVSKEQSK ddPTM_PC-9_AZD4547_30min_R2 2 ESLPPAAEPSPVSKEQSK 18 1 Q9NWT1 Q9NWT1 PAK1IP1 p21-activated protein kinase-interacting protein 1 1 ESLPPAAEPS(1)PVSKEQSK;ESLPPAAEPS(1)PVSKEQSK 105.96 0.00015583 26216000.0 127506.0 63110.0 133941.0 257820.0 209529.0 153653.0 92583.0 127102.0 91267.0 159893.0 True False 168050.25571044322 83509.0733166857 132164.8548245053 198383.5822792926 180439.5150838072 144045.05362007607 100822.70764296356 107461.30641339884 96091.18729472671 154295.19473764126 1.0891476950801393 0.5412292551215345 0.8565714249833529 1.2857405093957583 1.1694435163105432 0.9335679822369439 0.6534403603067442 0.6964656715079345 0.6227749830972842 1.0 17.235333606752945 -7.17195736577155 5.500735917758123 0.718668375553943 0.9792272221682301 0.230485617882216 0.21047322424124987 0.35388522663626554 16.94870784224962 0.08821567047222416 0.06777927820106104 6.73042724931448e-08 7.17195736577155 0.2605588466142871 ESLPPAAEPS(ph)PVSKEQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESLPPAAEPSPVSKEQSK 18 1 Q9NWT1 Q9NWT1 PAK1IP1 p21-activated protein kinase-interacting protein 1 1 ESLPPAAEPS(1)PVSKEQSK 161.02 2.2316999999999997e-06 7515600.0 27528.0 7374.2 15599.0 30015.0 30119.0 48989.0 28534.0 51287.0 36707.0 23696.0 True False 32187.946697216707 8106.2618416099995 15970.939319536936 28333.356859942924 24217.398161050576 46419.930599794316 25831.05295172967 49940.770593068315 37243.77043217862 27991.8972225672 1.1499022892691473 0.28959315537478797 0.5705558002213972 1.01219851711589 0.8651574406870284 1.658334561273337 0.9228046511582843 1.7841152457792617 1.3305196906107715 1.0 14.772721652127645 -6.362989844052892 1.5961353705055599 1.360283787483885 0.657092249256914 0.3968650300464869 0.3348776441690898 0.34281528079331075 1.7441969091561271 0.12091154908934379 0.15081961133158106 4.335210161286561e-07 6.362989844052892 -0.7031915382269709 ESLPPAAEPS(ph)PVSKEQSK ddPTM_PC-9_Lapatinib_30min_R1 2 ESLPPAAEPSPVSKEQSK 18 1 Q9NWT1 Q9NWT1 PAK1IP1 p21-activated protein kinase-interacting protein 1 1 ESLPPAAEPS(1)PVSKEQSK;ESLPPAAEPS(0.999)PVS(0.001)KEQSK 158.44 4.6654e-06 23153000.0 360590.0 105304.0 162810.0 132285.0 98251.0 117533.0 61071.0 62393.0 139246.0 90003.0 True False 355447.9204758925 105060.17505785867 149424.39026477447 142013.68018982402 92472.069348898 112506.38757280484 64232.957557302005 65292.006556844884 123562.64915461477 105559.89862854115 3.367262806178813 0.9952659714799369 1.4155412444131819 1.3453374059173882 0.8760151397483014 1.0658061350428913 0.6084977192270131 0.6185304022183981 1.1705453563329404 1.0 16.687702344762975 -4.761270111461204 24.99453479611501 1.006760661534178 3.3672654102025246 0.8867014580751402 0.25271643415250006 1.357386004192008 199859.66845173674 0.06989237875389818 0.39321988900795013 1.7327259856126656e-05 4.761270111461204 2.3605047486683466 ESLPVSGEESQLT(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 2 ESLPVSGEESQLTPEK 16 0 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 ESLPVSGEES(0.015)QLT(0.985)PEK;ESLPVSGEES(0.026)QLT(0.974)PEK 186.17 1.4703e-07 4991100.0 22003.9 28233.0 25277.0 22862.0 23785.0 29316.0 26347.0 30494.0 27257.0 24247.0 True False 29000.682490447736 37358.76512359356 24941.810464301594 17591.51911437897 20482.863308985125 27482.865885639436 28691.831959097904 25781.85298240926 28697.74937373162 23398.119910212423 1.2394449896715847 1.5966567086139185 1.0659749826059917 0.7518347278278934 0.8754063739986692 1.1745758202411882 1.2262451884681116 1.1018771200995694 1.2264980897548996 1.0 14.514104990333193 -5.287319747174952 19.74206625876026 1.0498984960577438 1.4180497266001493 0.44477803552946904 0.16320837293279655 45.744277968960745 34894.91283329101 0.04636605019855563 0.09669681720561465 5.160363001908639e-06 5.287319747174952 0.3681512305424055 ESLPVSGEESQLT(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 1 ESLPVSGEESQLTPEK 16 0 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 ESLPVSGEES(0.001)QLT(0.999)PEK 176.28 4.2806999999999994e-29 0.0 6544.5 10495.0 8799.9 9535.6 9454.0 9661.7 9587.8 10333.0 10708.0 8808.0 True False 6451.1742298856825 10470.699472310875 8076.406190596332 10236.879833829105 8897.93430727914 9248.491613522743 10084.209370534303 10813.10890247108 9501.95227976111 10330.451064077735 0.6244813696778903 1.0135762134066757 0.7818057643853099 0.9909421931657943 0.8613306671787148 0.8952650330712751 0.9761635099942835 1.0467218551638757 0.9198003282550189 1.0 13.334615628302362 -4.752864152366803 24.99996541745554 0.9377826802028892 0.624480781901925 0.6103525439934001 0.07621500880448978 225.36312531084525 656967.5595901039 0.018709548662396748 0.21372675862156412 1.7665903250220957e-05 4.752864152366803 -0.3133018983009642 ESLPVSGEESQLT(ph)PEKSPK ddPTM_PC-9_AZD4547_30min_R2 2 ESLPVSGEESQLTPEKSPK 19 1 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 ESLPVS(0.002)GEES(0.121)QLT(0.858)PEKS(0.018)PK;ESLPVSGEES(0.365)QLT(0.635)PEKS(0.001)PK 89.47 0.00076035 36188000.0 116557.0 94456.0 123685.0 137698.0 150312.0 132874.0 122902.0 117828.0 123779.0 133441.0 True False 153619.70146379137 124987.05481224637 122044.8560856567 105953.85351289294 129443.77337398248 124565.36777488267 133840.0399072782 99620.39001807946 130321.705240163 128769.27120627924 1.1929841648144728 0.970627958373904 0.9477793493926785 0.8228193925487267 1.0052380677578172 0.9673532094107902 1.0393787170921853 0.7736348049877106 1.0120559355453436 1.0 16.974428832116836 -4.751576428891566 3.5225002564408046 0.9404732823103018 1.2327730949825932 0.45315947484527064 0.08069109774945742 0.2908113654263081 5.695051223313221 0.019795938092539107 0.2374725657408736 1.771836202827206e-05 4.751576428891566 0.29229981267229144 ESLPVSGEESQLT(ph)PEKSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESLPVSGEESQLTPEKSPK 19 1 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 ESLPVSGEES(0.06)QLT(0.929)PEKS(0.011)PK;ESLPVSGEES(0.085)QLT(0.886)PEKS(0.029)PK 129.2 2.5996e-05 17737400.0 70141.0 60036.0 52112.0 66028.0 68045.0 69507.0 72070.0 60084.0 55297.0 51645.0 True False 82014.48595210246 65995.97731589845 53354.54771586058 62328.665225664285 54712.070715119626 65861.93055991961 65243.00785838501 58506.85866426026 56105.6140133539 61007.829678404945 1.3443272180707206 1.0817624174435951 0.8745524631364913 1.0216502628305573 0.8968040824190499 1.0795652116638543 1.0694202400299317 0.9590057370123107 0.9196461226224166 1.0 15.896706788017232 -4.819994013658433 3.2962376792216848 0.9813215834314187 1.3783595660720993 0.7396079831158804 0.06560718174401498 0.1475576756616256 2.5923583908981613 0.016936226705583275 0.1425378831632462 1.513582111600352e-05 4.819994013658433 0.3970379826406806 ESLPVSGEESQLT(ph)PEKSPK ddPTM_PC-9_Lapatinib_30min_R1 2 ESLPVSGEESQLTPEKSPK 19 1 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 ESLPVS(0.01)GEES(0.373)QLT(0.601)PEKS(0.017)PK;ESLPVSGEES(0.031)QLT(0.892)PEKS(0.078)PK 113.73 6.0346e-05 36728000.0 111316.0 143245.0 172830.0 179836.0 183576.0 167266.0 134608.0 131634.0 190670.0 143639.0 True False 109728.6134271455 142913.3250034467 158620.58454309267 193061.73935530943 172778.42060430252 160112.4230960903 141577.34359799762 137750.1961935428 169194.73675588836 168466.8097630633 0.6513366851397676 0.8483173938204458 0.9415539165618518 1.1459927307155466 1.0255932361235023 0.9504093021128442 0.8403871587353983 0.817669642983557 1.00432089260697 1.0 17.362104863429927 -4.851477260400361 2.264320201737285 0.9621420319567677 0.6009585750808458 0.5482238162308422 0.0879415281026408 0.45301471555313044 3.1404756239642335 0.026541342827212246 0.3135904499627114 1.4077409355553338e-05 4.851477260400361 -0.3611834568759219 ESLPVSGEESQLTPEKS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESLPVSGEESQLTPEKSPK 19 1 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 ESLPVSGEES(0.178)QLT(0.316)PEKS(0.506)PK;ESLPVS(0.003)GEES(0.067)QLT(0.453)PEKS(0.477)PK 106.28 0.00010591 4664800.0 46550.1 41332.5 31316.8 50217.0 53784.0 43639.8 47672.0 51630.0 41526.2 36780.0 True False 54430.1125236162 45435.71744302371 32063.511281625386 47403.50429571065 43245.41129167452 41351.252064522734 43156.16304460845 50274.767206506855 42133.44211514796 43447.92284968017 1.2527667366730482 1.0457511996654212 0.7379757000710429 1.0910418999710498 0.9953389818264432 0.9517428993691727 0.9932848388153988 1.1571270594556613 0.9697458325204633 1.0 15.406999586138097 ESLT(ph)PGREENPSSVLAQER ddPTM_PC-9_AZD4547_30min_R2 2 ESLTPGREENPSSVLAQER 19 1 A0A494C0P1;P04150-7;P04150-5;P04150-2;P04150-6;P04150-10;P04150;P04150-3;D6RDA9;Q3MSN4 A0A494C0P1 NR3C1 Glucocorticoid receptor 1 ES(0.027)LT(0.972)PGREENPSSVLAQER;ES(0.172)LT(0.828)PGREENPSSVLAQER 109.87 0.005159899999999999 6781200.0 25508.8 20637.8 26103.8 36448.5 31229.5 25725.9 23549.7 28879.1 24194.6 26425.9 True False 33620.067783998915 27308.565255824713 25757.646556080064 28045.861448711476 26893.822985408897 24117.255406173128 25645.57767818608 24416.49867069899 25473.477161745122 25500.737284417948 1.318395911813194 1.0708931648227844 1.010074582110969 1.0998059050570552 1.0546292323023219 0.9457473773085695 1.0056798512196994 0.9574820680035211 0.9989310064893895 1.0 14.638251338837375 -1.651723934574504 0.9770778154650833 1.0015775110115317 199.99999999998735 0.8322825163499267 0.04154741073742245 437.5992098306387 0.8917100678152945 0.014310623495993298 194504.85175856383 0.02229852135884458 1.651723934574504 198.99842248897582 ESLT(ph)PGREENPSSVLAQER ddPTM_PC-9_Lapatinib_30min_R1 1 ESLTPGREENPSSVLAQER 19 1 A0A494C0P1;P04150-7;P04150-5;P04150-2;P04150-6;P04150-10;P04150;P04150-3;D6RDA9;Q3MSN4 A0A494C0P1 NR3C1 Glucocorticoid receptor 1 ES(0.054)LT(0.945)PGREENPSSVLAQER 112.82 0.0035214 0.0 4622.0 5558.8 5923.9 6237.8 7113.5 9190.0 5387.0 4590.2 6449.2 5294.8 True False 4556.08943242901 5545.928940131655 5436.85980891528 6696.548620690799 6695.097915679093 8796.965122936335 5665.912501206565 4803.4774493489585 5722.823182913279 6209.999125122479 0.7336698992432066 0.8930643673838315 0.8755008977248526 1.0783493662019998 1.0781157582767045 1.4165807346652135 0.9123853944335003 0.7735069446171975 0.9215497567079622 1.0 12.600377349857997 -5.28244159393837 1.6386851722479552 1.0273004273818869 0.763709272100652 0.23140997920870565 0.16134731938601696 0.8059227357301801 3.671819319006418 0.053102773191599804 0.24543631039206304 5.218652825342821e-06 5.28244159393837 -0.2635911552812349 ESLTEAEVATEKEGEDGDQPT(ph)TPPKPLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESLTEAEVATEKEGEDGDQPTTPPKPLK 28 2 M0R0Q7;P18858-2;P18858;P18858-3;B4E135 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 ESLTEAEVAT(0.001)EKEGEDGDQPT(0.532)T(0.467)PPKPLK 50.158 0.0077498 22195000.0 54836.0 78031.0 47711.0 61689.0 63438.0 49148.0 65570.0 43056.0 45080.0 49444.0 True False 64118.651739631445 85777.40199108669 48848.61118497513 58232.76532843648 51007.77929349336 46570.59235989083 59358.73491430976 41925.82562160291 45739.209717018864 58407.80580151136 1.0977753890897288 1.4685948361523131 0.8363370360286866 0.9970031321897329 0.8733041516203214 0.797335077406482 1.0162808566380659 0.7178120295098989 0.7831009757917549 1.0 15.833873567808737 -5.274681754444189 24.82995188726738 0.8737590917435063 1.2831851126563345 0.6218067938107046 0.12647984680564353 367.4257856165988 688937.4400519109 0.03170523462546554 0.06664618438804482 5.31273612272502e-06 5.274681754444189 0.4094260209128282 ESLTEAEVATEKEGEDGDQPT(ph)TPPKPLK ddPTM_PC-9_Lapatinib_30min_R1 2 ESLTEAEVATEKEGEDGDQPTTPPKPLK 28 2 M0R0Q7;P18858-2;P18858;P18858-3;B4E135 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 ESLTEAEVATEKEGEDGDQPT(0.5)T(0.5)PPKPLK;ESLTEAEVAT(0.001)EKEGEDGDQPT(0.5)T(0.5)PPKPLK 61.903 0.00050093 72273000.0 127259.0 140518.0 112882.0 137968.0 150344.0 144998.0 131927.0 150623.0 120648.0 124544.0 True False 125444.26332355756 140192.63920439992 103601.27769712108 148114.62696775616 141501.06150767652 138796.77354684685 138757.53453623143 157621.4944562955 107059.35176023722 146071.2644555515 0.8587880976530424 0.9597550875385185 0.7092515977271234 1.01398880553147 0.9687125119036286 0.9501990282906174 0.9499303990652754 1.0790725680632323 0.7329254809922909 1.0 17.156312869519105 -5.806516149498701 24.999878395283815 0.9596833608436921 0.8543118503237798 0.20641640164405628 0.10133853608408178 200.89793511788795 111418.38869468705 0.027098920458409843 0.040194378117750514 1.5612909793561998e-06 5.806516149498701 -0.10537151051991234 ESLTEAEVATEKEGEDGDQPTT(ph)PPKPLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESLTEAEVATEKEGEDGDQPTTPPKPLK 28 2 M0R0Q7;P18858-2;P18858;P18858-3;B4E135 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 ESLT(0.001)EAEVAT(0.032)EKEGEDGDQPT(0.425)T(0.543)PPKPLK 55.588 0.0014812000000000002 17091000.0 51980.0 74606.0 50045.0 66820.0 59793.0 52790.0 60204.0 47220.0 51210.0 57612.0 True False 60779.18734820271 82012.39062612277 51238.262596719374 63076.29203336285 48076.99087764194 50021.599468516244 54501.0412807855 45980.52503372561 51958.84937019826 68056.59954365884 0.8930682366698675 1.2050615396014779 0.7528772072111777 0.9268210938587802 0.7064265802290074 0.7349999824253193 0.8008193422273862 0.6756218403805019 0.7634652586023821 1.0 16.054447448218546 -5.279312219776563 24.96512080176744 0.7831350865643659 1.0490648948383596 0.4255483109419931 0.11735478162158741 577.9725175093346 807322.4885116157 0.02891046365879471 0.06038827729620909 5.25639241847955e-06 5.279312219776563 0.2659298082739937 ESMAVAT(ph)DGGER ddPTM_PC-9_AZD4547_30min_R2 1 ESMAVATDGGER 12 0 D6RIW3;P49069 D6RIW3 CAMLG Calcium signal-modulating cyclophilin ligand 1 ES(0.019)MAVAT(0.981)DGGER 84.479 0.024907 15587000.0 0.0 0.0 0.0 1017.9 1776.5 0.0 0.0 2139.3 0.0 0.0 True False 0.0 0.0 0.0 783.2388813982308 1529.8636396221182 0.0 0.0 1808.7203412234585 0.0 0.0 0.0 ESMCSTPAFPVS(ph)PETPYVK ddPTM_PC-9_AZD4547_30min_R2 1 ESMCSTPAFPVSPETPYVK 19 0 Q68CZ2;Q68CZ2-2;E9PCX8 Q68CZ2 TNS3 Tensin-3 1 ESMCSTPAFPVS(0.991)PET(0.007)PY(0.002)VK 88.684 0.0020869 0.0 23681.0 18844.0 31466.0 41125.0 33700.0 25778.0 25429.0 33027.0 25249.0 36361.0 True False 31211.06540460069 24934.954485495564 31048.74028048085 31644.266624916243 29021.336704343033 24166.097584936997 27692.13173749957 27923.43603495868 26583.610593144873 35088.01245742706 0.8895079321597271 0.710640265411146 0.8848817047746113 0.9018540637863379 0.8271011856130399 0.6887280268227838 0.7892191605637097 0.7958112779639116 0.7576265719068376 1.0 15.09869060887905 -4.421071015320681 21.10373759451596 0.8104508570015445 12.022170271330381 0.05164398470414733 0.0885069024671768 1032.32356738133 213319.93396264195 0.020887256373431785 1751.4769388373375 3.792529649062578e-05 4.421071015320681 11.211719414328837 ESMEAS(ph)PEAMVK ddPTM_PC-9_AZD4547_30min_R2 6 ESMEASPEAMVK 12 0 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1;Q8IWC1-3 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 1 ES(0.001)MEAS(0.999)PEAMVK;ESMEAS(1)PEAMVK;ES(0.026)MEAS(0.974)PEAMVK;ESMEAS(1)PEAMVK;ES(0.203)MEAS(0.797)PEAMVK;ES(0.003)MEAS(0.997)PEAMVK 92.85600000000001 0.0049609 41856000.0 349377.0 284536.0 383254.0 407713.0 390363.0 397181.0 388975.0 447417.0 353630.0 372814.0 True False 460471.6185069535 376506.69759525376 378171.8015462848 313721.06695305696 336167.8356058597 372345.2092824456 423593.0214555771 378278.9832698426 372322.1598500464 359761.8953357497 1.2799343801466687 1.0465441239792137 1.051172473931276 0.8720241665957288 0.934417568853781 1.0349767835611174 1.1774260335721676 1.05147039798868 1.034912714984934 1.0 18.45668286413533 -4.738002784311971 3.3781937570700347 1.020341554658296 1.3292924604881962 0.5142837322441373 0.07541109966529984 0.3599288956065013 5.981252238586241 0.02155172579315157 0.30701794355139195 1.8280884960191598e-05 4.738002784311971 0.30895090582990026 ESMEAS(ph)PEAMVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ESMEASPEAMVK 12 0 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1;Q8IWC1-3 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 1 ES(0.005)MEAS(0.995)PEAMVK;ESMEAS(1)PEAMVK;ESMEAS(1)PEAMVK 85.973 0.0056035 30624400.0 217553.0 211343.0 244238.0 232456.0 273496.0 247097.0 258584.0 264611.0 220887.0 195263.0 True False 254380.42603238852 232323.7363227719 250061.5601977731 219432.2439525199 219906.42210746364 234138.79833059182 234089.05153396193 257665.24162852945 224117.054497851 230662.63619894287 1.1028245849622105 1.0072014269463059 1.0841008510025827 0.9513124776882506 0.9533681992509521 1.0150703303705018 1.0148546612987803 1.117065363834207 0.9716227048777575 1.0 17.815424802965232 -2.164000576054186 1.2659230140645228 1.0124644358207435 86.2283425250908 0.21780799644106352 0.050398441833898106 2299.0359669693717 4.991533016429799 0.01516150080000515 568295.5129346973 0.0068548731721223425 2.164000576054186 85.21587808927005 ESMEAS(ph)PEAMVK ddPTM_PC-9_Lapatinib_30min_R1 7 ESMEASPEAMVK 12 0 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1;Q8IWC1-3 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 1 ES(0.002)MEAS(0.998)PEAMVK;ESMEAS(1)PEAMVK;ES(0.006)MEAS(0.994)PEAMVK;ESMEAS(1)PEAMVK;ES(0.001)MEAS(0.999)PEAMVK;ESMEAS(1)PEAMVK;ESMEAS(1)PEAMVK 178.15 0.00056231 38262000.0 368145.0 334017.0 378048.0 331607.0 389484.0 357955.0 314085.0 303689.0 374225.0 317028.0 True False 362895.1847904757 333243.6041584441 346966.35274748073 355994.4849885232 366575.3168750057 342646.09908386035 330346.7844702917 317799.4996112007 332075.83973604796 371825.8673867436 0.9759815457191446 0.8962356667128559 0.9331420516437443 0.957422590016434 0.985879006889328 0.921523027679694 0.8884448701539405 0.8546998137723727 0.8930950449196402 1.0 18.504267614388773 -6.9985205560648875 24.76536138162897 0.8980990592565973 0.9470092494134172 0.1558009532531951 0.04196961436081014 64.9102516212849 1086544.2218640675 0.014624494169103205 0.012803640157333086 1.0034123544213933e-07 6.9985205560648875 0.048910190156819966 ESNCYDPER ddPTM_PC-9_AZD4547_30min_R2 1 ESNCYDPER 9 0 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 102.07 0.015187 10771000.0 27703.0 29651.0 38725.0 48343.0 35287.0 39365.0 33368.0 35537.0 29372.0 36998.0 False True 36511.97774180368 39235.105893092186 38211.481197534515 37198.268241904574 30388.009147957033 36903.50032706358 36337.68735761866 30045.5732090207 30924.543955873552 35702.71128131476 1.022666806845912 1.0989391137256885 1.0702683305044325 1.0418891705116111 0.8511400971348859 1.0336329932000783 1.017785094003105 0.8415487824518593 0.8661679420424887 1.0 15.12374601692934 -6.092377856663807 7.00511237140911 0.9363861224254318 1.0656795097717515 0.4541039849005952 0.0665731089276655 0.24818378697477553 16.198013255211293 0.020705838497614894 0.026896061168612408 8.083922537671083e-07 6.092377856663807 0.12929338734631968 ESNCYDPER ddPTM_PC-9_Lapatinib_30min_R1 1 ESNCYDPER 9 0 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 100.25 0.017884 12175000.0 18964.0 22261.0 23138.0 20130.0 19582.0 20988.0 20588.0 23528.0 18920.0 17706.0 False True 18693.569882428324 22209.456022211754 21235.682955262895 21610.42735171147 18430.22525969327 20090.39216541761 21653.945902142317 24621.19677318685 16789.030363567457 20766.458508237996 0.9001809275766803 1.0694869331427563 1.0225953041939606 1.0406409616323686 0.8874996789838793 0.9674443120596516 1.0427365789671001 1.18562328590692 0.8084686349820936 1.0 14.341967580891156 -7.261549976046967 24.23800320004534 1.024675730557249 0.9856257840714 0.007752915985080877 0.10112909591539249 29.43002511338955 6448256.508513128 0.03972355635161896 0.02869206566063253 5.4758308470513374e-08 7.261549976046967 -0.03904994648584892 ESNLQLTDFS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 3 ESNLQLTDFSPSR 13 0 Q5BKX5-3;Q5BKX5 Q5BKX5-3 C19orf54 UPF0692 protein C19orf54 1 ESNLQLT(0.003)DFS(0.765)PS(0.232)R;ESNLQLT(0.165)DFS(0.798)PS(0.037)R;ESNLQLT(0.066)DFS(0.467)PS(0.467)R 156.29 4.4211e-05 13686000.0 54491.0 50588.0 68714.0 73470.0 66638.0 65261.0 58628.0 73272.0 51857.0 64775.0 True False 71818.00451678975 66939.581697742 67802.80746306998 56532.626600184725 57386.46395560865 61180.21935334682 63845.77842251464 61949.49602305665 54598.05515183628 62507.24696597554 1.1489548492814332 1.070909133690996 1.0847191446453717 0.9044171571171105 0.9180769709285984 0.9787700198450421 1.0214140203177993 0.9910770195458698 0.8734676025894332 1.0 15.931735842216584 -5.681191705721297 6.619454709200804 0.957325308870428 1.1010828147880825 0.6692058789667521 0.04715962829853625 0.1359967631039893 9.06586761976444 0.01343067129164324 0.023349038112752588 2.0835709528184294e-06 5.681191705721297 0.14375750591765446 ESNLQLTDFS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ESNLQLTDFSPSR 13 0 Q5BKX5-3;Q5BKX5 Q5BKX5-3 C19orf54 UPF0692 protein C19orf54 1 ESNLQLT(0.036)DFS(0.776)PS(0.188)R;ESNLQLT(0.017)DFS(0.863)PS(0.12)R;ESNLQLT(0.336)DFS(0.572)PS(0.092)R 140.96 7.507899999999999e-05 10232500.0 45088.2 40247.4 51309.2 53071.0 55751.0 48922.8 52461.0 43354.0 39124.8 40030.4 True False 52720.74172745732 44242.89588619979 52532.60591922458 50097.603928503486 44826.991761902136 46357.20224433275 47491.51429525096 42216.00343736002 39696.92618315039 47287.59463952794 1.1148958226644032 0.9356131607763557 1.1109172779812384 1.059423815281707 0.9479651503447593 0.9803248102956486 1.0043123287889244 0.892750070270469 0.8394786515524629 1.0 15.529174138179977 -6.907153065058186 0.8937864685042365 0.9118363297277325 1.0494060236430078 0.3849114813700768 0.06666651095766143 0.62019138977101 1.0496729753148248 0.044384693736603774 0.03552260412283318 1.2383600554006788e-07 6.907153065058186 0.1375696939152753 ESNLQLTDFS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 3 ESNLQLTDFSPSR 13 0 Q5BKX5-3;Q5BKX5 Q5BKX5-3 C19orf54 UPF0692 protein C19orf54 1 ESNLQLT(0.01)DFS(0.769)PS(0.222)R;ESNLQLT(0.162)DFS(0.668)PS(0.169)R;ESNLQLT(0.002)DFS(0.518)PS(0.48)R 162.26 0.0003241 14615500.0 61338.0 68228.0 62501.0 55148.6 63505.2 60068.0 67044.0 59496.5 65036.0 42949.5 True False 60463.3088719884 68070.02225791583 57362.40904083696 59204.412014336565 59769.94899202696 57499.03166534709 70515.21027118852 62260.92459265175 57710.96082055886 50373.26384838855 1.2003055639588585 1.3513125229048146 1.13874711818325 1.1753141943021133 1.1865411217331516 1.1414593233109807 1.3998539082840136 1.235991473175973 1.1456664986857912 1.0 15.620370590500558 -8.591821089271923 3.0610968378042256 1.0004275834357348 1.2287327186631571 0.42921830985112974 0.08101583911934457 0.3156667145981606 7.394463062050114 0.08012166280705732 0.021310270041083004 2.5596401318577323e-09 8.591821089271923 0.22830513522742235 ESNLQLTDFSPS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESNLQLTDFSPSR 13 0 Q5BKX5-3;Q5BKX5 Q5BKX5-3 C19orf54 UPF0692 protein C19orf54 1 ESNLQLT(0.145)DFS(0.193)PS(0.662)R 135.23 5.0058999999999996e-05 2853200.0 12561.0 16576.0 13234.0 9538.6 18531.0 15213.0 11520.0 17241.0 16626.0 13985.0 True False 14687.329208941404 18221.555733032394 13549.548750224492 9004.18316655845 14899.983575896553 14415.203499044084 10428.742202422576 16788.4420183495 16869.12379669821 16520.369794800907 0.889043610486469 1.1029750519729205 0.8201722430262212 0.545035206741688 0.9019158627178974 0.8725714786106462 0.6312656636599373 1.0162267689451454 1.021110544511362 1.0 14.011958360202351 -7.885841483054087 23.5489885121594 1.0140942042408656 0.8278100841824438 0.26700711295458746 0.1434797631330515 7.392779407788775 1484.5165658733522 0.08357344955310757 0.04014739308996787 1.3006442249301969e-08 7.885841483054087 -0.18628412005842176 ESNYFGLS(ph)PEER ddPTM_PC-9_AZD4547_30min_R2 4 ESNYFGLSPEER 12 0 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 ESNYFGLS(1)PEER;ESNYFGLS(1)PEER;ESNYFGLS(1)PEER;ESNYFGLS(1)PEER 241.76 1.6255000000000001e-22 71836000.0 96594.6 77069.5 103803.4 156794.9 123676.0 103007.0 89672.0 129354.0 93512.7 103792.0 True False 127309.67350750591 101980.70869878495 102426.89909206328 120648.25826205657 106505.72220315535 96565.95600634691 97652.63428231794 109365.31155921046 98455.59041203914 100158.27367182607 1.2710849422649082 1.0181955515021173 1.0226504045753673 1.2045760558670073 1.063374180670556 0.9641335904285893 0.9749832011110935 1.091924885981479 0.98300007380952 1.0 16.611922075740118 -6.5240817996898475 20.08446390692949 1.0075853731022573 1.1161448432752914 0.3629362555069682 0.07803068291425662 4.302123823940935 71784.02606325921 0.02559791468938509 0.02593334558408974 2.9917010944037584e-07 6.5240817996898475 0.10855947017303413 ESNYFGLS(ph)PEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ESNYFGLSPEER 12 0 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 ESNYFGLS(1)PEER;ESNYFGLS(1)PEER;ESNYFGLS(1)PEER;ESNYFGLS(1)PEER 173.33 6.3271e-05 68988000.0 75946.0 75708.0 86163.0 88222.0 103024.0 84516.0 88935.0 89033.0 70839.0 61498.0 True False 88802.15779812608 83223.78990325857 88217.45269499738 83279.20735958319 82837.18676397203 80083.83217808511 80510.43296635874 86695.97808826105 71874.88636077847 72647.10058209993 1.2223771779820587 1.1455899717457507 1.214328610338703 1.1463528026898706 1.1402683121586674 1.1023679064463252 1.1082401406422588 1.1933852472237927 0.9893703366667915 1.0 16.148617599165334 -7.915338437094411 0.17140231761540387 0.9309864725201289 1.2677018637658255 0.6140381295270809 0.04733396957050855 2.510335761197756 0.447524183855268 0.35366320861114914 0.3637006508163688 1.2152386201515803e-08 7.915338437094411 0.3367153912456966 ESNYFGLS(ph)PEER ddPTM_PC-9_Lapatinib_30min_R1 3 ESNYFGLSPEER 12 0 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 ESNYFGLS(1)PEER;ESNYFGLS(1)PEER;ESNYFGLS(1)PEER 178.67 0.00024631 43222400.0 69545.6 66743.0 82582.0 63182.1 78765.0 65366.0 76626.0 64679.9 82711.0 66887.0 True False 68553.86699089898 66588.46068417783 75792.42673573873 67828.72240330694 74132.19755794817 62570.448555588264 80593.31934610252 67685.16427958387 73395.21619455742 78448.32882867471 0.8738728793141726 0.8488193652869528 0.9661445676078546 0.864629284218913 0.9449812209492359 0.7976007837239905 1.0273427178048917 0.8627993137674508 0.9355867395830328 1.0 16.259455093584585 -14.522878727708433 0.12711410663164333 1.3307739097461218 0.859165442731843 0.21595592874025582 0.06186887720369924 230.07880919011043 1.853133512034017 19.326963651113868 0.4739576538423671 3.0000001213824218e-15 14.522878727708433 -0.4716084670142787 ESNYFGLS(ph)PEERR ddPTM_PC-9_AZD4547_30min_R2 1 ESNYFGLSPEERR 13 1 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 ESNYFGLS(1)PEERR 94.61 0.0017075 5056200.0 11408.0 6958.6 21051.0 29348.0 23674.0 16469.0 8109.1 23028.0 13451.0 16082.0 True False 15035.506698859204 9207.831367160346 20771.849985520952 22582.272022080033 20387.273742985657 15439.190826531443 8830.794190591758 19469.55173079689 14161.992399239241 15518.974074979838 0.9688466921985458 0.5933273245172497 1.3384808741326504 1.4551394900831658 1.3136998389509935 0.9948589869367058 0.5690320860081229 1.2545643569433043 0.9125598335827905 1.0 13.9217455668515 -6.986034940784362 24.240615966343942 0.9304945812954257 1.1351995151656245 0.10978680046663758 0.27160173234866936 414.2703194483877 719088.1469218933 0.10445144906151796 0.09206942555901239 1.0326783191841906e-07 6.986034940784362 0.20470493387019872 ESNYFGLS(ph)PEERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESNYFGLSPEERR 13 1 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 ESNYFGLS(1)PEERR 71.143 0.012185 4180300.0 15546.0 6256.5 30496.0 25138.0 32856.0 38027.0 24448.0 34643.0 33940.0 19904.0 True False 18177.63075250401 6877.603972231965 31223.14029672403 23729.599358495612 26418.10265876949 36032.797177292414 22132.10845180791 33733.65795729259 34436.30829182833 23512.437640022705 0.7731070266216113 0.2925091850334121 1.3279414399626612 1.009236035914169 1.1235799138835687 1.5324994255788111 0.941293658728723 1.4347154673521132 1.4645996650390298 1.0 14.521136496969401 -5.268786218814734 24.99973939017727 1.2336757779501322 0.5328080941658366 0.603377748413597 0.22583126916404833 316.2500510869819 1076134.6646466905 0.057171620633087054 0.12293071893649844 5.3853481070244115e-06 5.268786218814734 -0.7008676837842955 ESNYFGLS(ph)PEERR ddPTM_PC-9_Lapatinib_30min_R1 2 ESNYFGLSPEERR 13 1 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 ESNYFGLS(1)PEERR;ESNYFGLS(1)PEERR 75.877 0.0081913 8725400.0 87341.0 23975.0 56207.0 28777.0 28294.0 38899.0 22124.5 20171.0 56667.0 27993.0 True False 86095.50132362236 23919.487360519623 51585.877425294355 30893.35657725787 26629.802548144267 37235.38044799789 23269.998353990097 21108.218297855823 50284.5657300358 32831.5527516721 2.6223402217623577 0.7285518154270487 1.571228684048978 0.9409654429361244 0.8111039629945015 1.1341340060774772 0.7087693515441473 0.6429247637939022 1.531592675813203 1.0 15.002795362605726 -4.755556827725238 24.99823844193956 1.0005292894878808 2.6223428491918774 0.7113352432422175 0.3085423332679992 101.97678300186142 433312.95476936555 0.0748038386617261 0.6563679490676754 1.7556711484169366e-05 4.755556827725238 1.6218135597039967 ESPFSTS(ph)ASPLLSGSQHFDVPPR ddPTM_PC-9_AZD4547_30min_R2 1 ESPFSTSASPLLSGSQHFDVPPR 23 0 O14980 O14980 XPO1 Exportin-1 1 ESPFS(0.007)T(0.039)S(0.691)AS(0.261)PLLSGSQHFDVPPR 148.72 2.0675e-06 6246000.0 12328.0 9084.7 14298.0 18040.0 14076.0 17509.0 13093.0 20290.0 16083.0 17438.0 True False 16248.04756167043 12021.151614008788 14108.399177852756 13881.156715221623 12121.790369446067 16414.159462125142 14258.251635498125 17154.646717816082 16933.11454590475 16827.500927714103 0.965565096770291 0.7143753350927181 0.8384132164638235 0.8249089852884816 0.7203559471794203 0.9754365507175099 0.8473184281342367 1.0194411393294405 1.0062762509207002 1.0 14.038533315759706 -7.445882481710048 1.1904781145708203 1.0151296421195655 0.8153460381163412 0.46257025097948967 0.08153956461603755 0.4063397621720581 1.0887910339014868 0.05709179461422812 0.027971969688864916 3.5819334962839985e-08 7.445882481710048 -0.19978360400322426 ESPFSTSAS(ph)PLLSGSQHFDVPPR ddPTM_PC-9_AZD4547_30min_R2 2 ESPFSTSASPLLSGSQHFDVPPR 23 0 O14980 O14980 XPO1 Exportin-1 1 ESPFST(0.001)S(0.006)AS(0.992)PLLSGSQHFDVPPR;ES(0.001)PFS(0.06)T(0.019)S(0.224)AS(0.694)PLLS(0.001)GS(0.001)QHFDVPPR 163.15 6.6667e-09 6194700.0 11465.2 8716.3 27111.2 41337.4 37943.2 40436.7 21641.5 49425.4 30167.9 30861.7 True False 15110.895109025287 11533.673518463442 26751.687773856618 31807.701086463538 32675.441627306478 37908.18675664606 23567.551574859288 41787.84011270315 31762.513605011514 29781.24127657039 0.5073964167139463 0.3872798118571793 0.8982730949801884 1.068044840410578 1.097181991974694 1.2728880708699448 0.7913555837378895 1.4031597852027289 1.0665275268428733 1.0 14.862116265982296 -5.42754423612374 2.64704295278768 1.1110113025327892 0.436967323617533 0.7300578895237309 0.15601289912633223 0.13225945393160313 1.7799309066297089 0.04160675049391291 0.10441025730612301 3.7364206521989145e-06 5.42754423612374 -0.6740439789152562 ESPFSTSAS(ph)PLLSGSQHFDVPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ESPFSTSASPLLSGSQHFDVPPR 23 0 O14980 O14980 XPO1 Exportin-1 1 ESPFSTS(0.001)AS(0.999)PLLSGSQHFDVPPR;ESPFS(0.002)T(0.001)S(0.042)AS(0.954)PLLSGSQHFDVPPR;ESPFSTSAS(1)PLLSGSQHFDVPPR;ESPFS(0.002)T(0.008)S(0.025)AS(0.965)PLLSGSQHFDVPPR 179.76 9.499299999999999e-15 10216800.0 15137.2 23658.6 42733.0 35354.1 47185.0 33259.1 35613.1 26639.399999999998 30054.100000000002 24093.7 True False 17699.628986672065 26007.26945375965 43751.91678580496 33373.32439653867 37939.43797035663 31514.93424670066 32239.569351484017 25940.143976777425 30493.584355728864 28461.697084375737 0.6218753904308963 0.9137638341332969 1.5372209413971631 1.17256972757465 1.332999850918369 1.1072753024274515 1.1327353128630608 0.9114053845727091 1.071390235983804 1.0 14.796734067493142 -7.734248842156823 22.00651839663321 0.9935486542681816 1.1353521895742273 0.05239405695566157 0.2298590185259596 169.96633230174055 137561.02569856294 0.1150924707962609 0.06640372379909096 1.8439585646076017e-08 7.734248842156823 0.14180353530604572 ESPFSTSAS(ph)PLLSGSQHFDVPPR ddPTM_PC-9_Lapatinib_30min_R1 4 ESPFSTSASPLLSGSQHFDVPPR 23 0 O14980 O14980 XPO1 Exportin-1 1 ESPFST(0.003)S(0.017)AS(0.981)PLLSGSQHFDVPPR;ESPFSTS(0.002)AS(0.998)PLLSGSQHFDVPPR;ESPFSTS(0.003)AS(0.997)PLLSGSQHFDVPPR;ESPFS(0.001)T(0.001)S(0.008)AS(0.987)PLLS(0.004)GSQHFDVPPR 165.49 2.6629e-11 7392700.0 17228.8 20581.5 39738.1 25444.2 35425.299999999996 40814.1 34393.1 35717.6 45613.299999999996 28476.0 True False 16983.114152625036 20533.844801273583 36470.98681150196 27315.451347362963 33341.653502819514 39068.57608531404 36173.80643126924 37377.170089509425 40475.84982465707 33398.03865811506 0.5085063325567017 0.6148218765620318 1.0920098388065145 0.8178759126241639 0.9983117225573411 1.1697865400195036 1.0831117001081656 1.1191426679909995 1.2119229586801572 1.0 15.027475760653097 -4.666810577978494 0.6570871218141497 1.116629014006922 1.490415847495393e-16 0.7748091813809623 0.10733718114913615 1.705031587397265 0.5016245895111683 0.048763829495914617 1.4808766701957972 2.153720897499028e-05 4.666810577978494 -1.1166290140069217 ESPRPLQLPGAEGPAIS(ph)DGEEGGGEPGAGGGAAGAAGAGR ddPTM_PC-9_AZD4547_30min_R2 10 ESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGR 40 1 Q6PKG0;A0A0B4J210 Q6PKG0 LARP1 La-related protein 1 1 ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ES(0.072)PRPLQLPGAEGPAIS(0.928)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ES(0.372)PRPLQLPGAEGPAIS(0.628)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR 152.93 3.2541e-33 973176000.0 132611.5 163471.40000000002 203525.2 211775.50000000003 203081.0 217850.9 177531.59999999998 239045.59999999998 181493.4 189183.09999999998 True False 174779.19850944655 216310.33319254083 200826.3228669965 162953.93037385884 174886.7085832254 204228.64878448157 193331.5684757201 202106.59524141852 191086.7705978801 182559.85725185383 0.9573802321083472 1.1848734790262565 1.1000574052265106 0.8926054874651481 0.9579691352516628 1.118694174386509 1.0590037228666649 1.1070702961965984 1.0467074935004075 1.0 17.47801004309693 -6.778259394387295 24.997981346365474 1.0725312954821857 1.0253440611702478 0.07266374395150721 0.08200264169502787 791.920117158017 1176947.5939858085 0.030981515590241003 0.027392993894085338 1.6662517003831755e-07 6.778259394387295 -0.04718723431193794 ESPRPLQLPGAEGPAIS(ph)DGEEGGGEPGAGGGAAGAAGAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 ESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGR 40 1 Q6PKG0;A0A0B4J210 Q6PKG0 LARP1 La-related protein 1 1 ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR 130.91 2.517e-32 605281100.0 145353.4 204843.2 250756.69 222902.3 257879.4 187453.5 200595.7 188637.66 179866.07 169591.8 True False 169958.85975948875 225178.67913445362 256735.6804896421 210413.8067900067 207349.78277276253 177623.10846697295 181593.82310889775 183686.12130312243 182496.27100057635 200337.45085204986 0.8483628948888052 1.1239969270685646 1.2815161588496131 1.050296916003979 1.0350026013153741 0.8866195896549989 0.9064397212631283 0.9168835907709312 0.9109443602501995 1.0 17.61207261654623 -6.564884400363553 2.963126759184445 0.9179886858151932 1.0923227792951027 0.32353381320482677 0.10327351775279331 0.2941093976956378 5.275726507652232 0.037203454299547606 0.038605615248333364 2.7234261277269513e-07 6.564884400363553 0.17433409347990947 ESPRPLQLPGAEGPAIS(ph)DGEEGGGEPGAGGGAAGAAGAGR ddPTM_PC-9_Lapatinib_30min_R1 7 ESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGR 40 1 Q6PKG0;A0A0B4J210 Q6PKG0 LARP1 La-related protein 1 1 ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR 146.0 1.4993e-32 869571000.0 84333.3 177755.3 157556.0 145783.4 190490.4 157179.4 157578.8 155043.1 179633.4 137433.9 True False 83130.69167716682 177343.71852410314 144602.3538637482 156504.7975551657 179286.12919053572 150457.2034650772 165737.45922501007 162246.9684386642 159401.19486843856 161189.16649583916 0.5157337399552389 1.1002210780008033 0.897097224381273 0.970938686249771 1.1122715818197602 0.9334200724275166 1.0282171117826848 1.0065624878260806 0.9889076191268303 1.0 17.29839525820379 -4.754316304905517 24.999905590161926 1.0019192172076772 0.5157328960392566 0.845039864356623 0.06274286393076232 88.19185467152776 309500.9403559604 0.01491289893187501 0.14710943513659003 1.7606932330548113e-05 4.754316304905517 -0.48618632116842053 ESPRPLQLPGAEGPAIS(ph)DGEEGGGEPGAGGGAAGAAGAGRR ddPTM_PC-9_AZD4547_30min_R2 3 ESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGRR 41 2 Q6PKG0;A0A0B4J210 Q6PKG0 LARP1 La-related protein 1 1 ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGRR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGRR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGRR 55.527 1.9520999999999998e-05 186759100.0 8702.4 2582.06 13144.900000000001 45433.4 31270.8 20269.8 15030.6 18219.1 11907.400000000001 18418.0 True False 11469.58217883522 3416.6604000646726 12970.590037274917 34959.43156903269 26929.389193298786 19002.32620168967 16368.294281869552 15403.756728268265 12536.800854561103 17773.191426002893 0.6453304813931594 0.19223674117783715 0.7297839609322174 1.9669754705891278 1.5151690288948336 1.0691566723288932 0.9209541432115608 0.8666849053193648 0.7053770228468512 1.0 14.117415140323116 -5.529180310855055 24.999379984950895 1.1616029458064356 0.42934014692272193 0.4126180560810997 0.35555536046277875 152.35858427237656 604430.5518887263 0.10609890227044178 0.18437805695743437 2.9567846106293748e-06 5.529180310855055 -0.7322627988837137 ESPRPLQLPGAEGPAIS(ph)DGEEGGGEPGAGGGAAGAAGAGRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGRR 41 2 Q6PKG0;A0A0B4J210 Q6PKG0 LARP1 La-related protein 1 1 ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGRR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGRR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGRR 61.669 5.7453e-06 91809000.0 20283.6 7729.4 12996.0 24921.1 25697.6 41447.4 24743.4 34054.1 34345.0 18937.1 True False 23717.21286063878 8496.723750174979 13305.873927604454 23524.85156229633 20662.33975176512 39273.82538002235 22399.526025297135 33160.21595830147 34847.23065064359 22370.24632399887 1.0602124141652782 0.37982253870220767 0.5948022983247114 1.0516134342722367 0.9236527596747337 1.7556277571199235 1.001308868077454 1.4823357542883688 1.5577490808967704 1.0 14.449293521885465 -6.235852163126409 1.6762844629096076 1.3575797044261664 0.6640660398445727 0.4715473741971439 0.29173022620651673 0.29588593696951954 1.6458973312855443 0.10031834300273401 0.13729343731258908 5.809621474359543e-07 6.235852163126409 -0.6935136645815937 ESPRPLQLPGAEGPAIS(ph)DGEEGGGEPGAGGGAAGAAGAGRR ddPTM_PC-9_Lapatinib_30min_R1 3 ESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGRR 41 2 Q6PKG0;A0A0B4J210 Q6PKG0 LARP1 La-related protein 1 1 ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGRR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGRR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGRR 72.633 4.4706000000000003e-08 200694500.0 87915.0 26547.9 27263.0 30893.9 17937.1 19226.1 4344.0 7816.6 30536.3 10665.900000000001 True False 86661.31597836364 26486.42996864811 25021.54137822335 33165.94046502923 16882.07504369544 18403.844521228097 4568.911064644759 8179.787771901236 27096.980332505544 12509.486603581598 6.927647690477689 2.1173075129290093 2.0002052978784453 2.6512631186265847 1.3495417980512425 1.4711910332082598 0.3652356974695214 0.6538867685872317 2.166114501033751 1.0 13.61073496124619 -3.1486632025269685 1.1241198757158684 1.331120797644882 199.99999999998025 0.8562634727095353 0.6662818351930284 21.43280752731319 0.9619395808657419 0.2142818418644892 10161.36648350736 0.0007101282623852955 3.1486632025269685 198.66887920233538 ESPSS(ph)TTPPIEISSSR ddPTM_PC-9_AZD4547_30min_R2 1 ESPSSTTPPIEISSSR 16 0 Q9HC44 Q9HC44 GPBP1L1 Vasculin-like protein 1 1 ES(0.012)PS(0.026)S(0.693)T(0.156)T(0.112)PPIEISSSR 100.18 0.001811 3382800.0 22025.0 17400.0 30995.0 34586.0 30137.0 22728.0 16853.0 28007.0 24157.0 24268.0 True False 29028.49185154047 23024.20972445462 30583.98604822676 26612.732048373335 25952.997752486226 21306.814567090085 18352.884351412955 23679.161686834643 25433.889702507055 23418.384706604305 1.2395599532257253 0.9831681396010835 1.3059818784000785 1.136403401933532 1.1082317622516094 0.9098328016227896 0.7836955700124437 1.0111355665003143 1.0860650732812647 1.0 14.515353948294681 -6.639502029421572 4.341473871001272 0.9484596204433909 1.1589169508412636 0.4622203346455426 0.1068376074269718 0.20480742135559568 6.7842867804914695 0.03715203268818326 0.03696357080079665 2.2934959131091247e-07 6.639502029421572 0.21045733039787262 ESPSST(ph)GSSTWK ddPTM_PC-9_AZD4547_30min_R2 1 ESPSSTGSSTWK 12 0 Q6NV74;C9JFM2;C9JXD6;C9JK00 Q6NV74 KIAA1211L Uncharacterized protein KIAA1211-like 1 ESPS(0.001)S(0.029)T(0.944)GS(0.019)S(0.005)T(0.001)WK 118.61 0.0011420999999999998 0.0 6476.3 7620.7 9589.5 15253.0 15268.0 8488.6 10497.0 13586.0 12784.0 13849.0 True False 8535.628684591678 10083.942244089158 9462.336964332006 11736.656506500853 13148.30174486378 7957.80650009684 11431.212664616502 11486.595875221748 13459.736140946734 13364.150725307521 0.638695930630883 0.7545516697139104 0.7080387791805804 0.8782194056129056 0.9838486571365144 0.5954592000393443 0.8553639434019074 0.859508105776578 1.0071523748574762 1.0 13.706080538618078 -2.4332830085540036 0.10951000470045419 1.1034106095746672 1.2479778764329926e-10 0.43088013352410026 0.10666923248124266 96.69375520262005 0.9116906281879281 1.1439773996674454 15.86270311311115 0.003687372321726631 2.4332830085540036 -1.1034106094498695 ESPT(ph)QISIGAFPSTK ddPTM_PC-9_AZD4547_30min_R2 1 ESPTQISIGAFPSTK 15 0 A0A2R8YH03;Q5VWN6;Q5VWN6-2 A0A2R8YH03 FAM208B Protein FAM208B 1 ES(0.022)PT(0.977)QIS(0.001)IGAFPSTK 109.72 0.0014699000000000001 8568000.0 25946.0 30037.0 27355.0 22982.0 30866.0 32522.0 33130.0 33296.0 28008.0 26367.0 True False 34196.28828967397 39745.872844450765 26992.254826560507 17683.854968360494 26580.788685942196 30488.3941988254 36078.50581868576 28150.868265963745 29488.445700534754 25443.899355490204 1.3439877202742982 1.5620983359956 1.0608537020775552 0.6950135559526464 1.044682197275186 1.19825950310744 1.4179629197008614 1.106389703584857 1.1589593752331766 1.0 14.635032164548196 -5.269320130677937 24.76127112134849 1.0895953724916216 1.4530430307538822 0.4070178438204324 0.1775043998792388 505.69739955829675 1588902.5714258056 0.05161660020987879 0.11065820140897643 5.378731549204112e-06 5.269320130677937 0.36344765826226055 ESPT(ph)QISIGAFPSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESPTQISIGAFPSTK 15 0 A0A2R8YH03;Q5VWN6;Q5VWN6-2 A0A2R8YH03 FAM208B Protein FAM208B 1 ES(0.374)PT(0.391)QIS(0.234)IGAFPSTK 96.06700000000001 0.0066416 7413000.0 26487.0 38970.0 34889.0 28233.0 34848.0 21469.0 31440.0 24821.0 20381.0 24800.0 True False 30970.725957903895 42838.684056242295 35720.8860772693 26651.196542621008 28019.784558461128 20343.1278459855 28461.775594111616 24169.475050023364 20679.033567936156 29296.043683308024 1.0571641103726934 1.4622685752155145 1.219307510031532 0.909719989180861 0.9564357857107487 0.6943984677895733 0.9715228411653499 0.8250081584836788 0.7058643751176008 1.0 14.838418227000398 -5.769526233752354 3.388009906418929 0.8535591092203075 1.2796689144694582 0.6332718566330224 0.13302290306565234 0.13417973824863932 3.2194724260566505 0.03664667756927626 0.06241162215402545 1.700097255405789e-06 5.769526233752354 0.42610980524915065 ESQLAHIKDEPPPLS(ph)PAPLTPATPSSLDPFFSR ddPTM_PC-9_AZD4547_30min_R2 2 ESQLAHIKDEPPPLSPAPLTPATPSSLDPFFSR 33 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 ES(0.001)QLAHIKDEPPPLS(0.945)PAPLT(0.047)PAT(0.004)PS(0.001)S(0.001)LDPFFSR;ESQLAHIKDEPPPLS(0.928)PAPLT(0.049)PAT(0.014)PS(0.004)S(0.004)LDPFFS(0.001)R 61.438 0.00016435 140293000.0 94382.0 80531.0 185366.0 315200.0 238430.0 188257.0 120747.0 194169.0 131268.0 180172.0 True False 124393.51273244449 106561.070880463 182907.92572400713 242535.50979145532 205328.11010137975 176485.2600297732 131493.2490820664 164164.6426097403 138206.55849106674 173864.23312008826 0.7154634998822658 0.6128981732939927 1.0520158312128083 1.3949706931611157 1.1809680830649012 1.0150751357116365 0.756298444610191 0.944211697044967 0.7949108106415842 1.0 17.407601650281478 -10.618302179421695 17.522857719294144 0.9999999995028617 0.9516727989402912 0.004184200149256023 0.22283225486139718 0.0 0.0 0.24248533414852494 0.05881133207985657 2.408229214571428e-11 10.618302179421695 -0.04832720056257045 ESQLAHIKDEPPPLS(ph)PAPLTPATPSSLDPFFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESQLAHIKDEPPPLSPAPLTPATPSSLDPFFSR 33 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 ESQLAHIKDEPPPLS(0.972)PAPLT(0.014)PAT(0.007)PS(0.003)S(0.003)LDPFFS(0.001)R;ESQLAHIKDEPPPLS(0.973)PAPLT(0.023)PAT(0.002)PSSLDPFFSR 62.787 8.9731e-05 198138000.0 48734.0 25410.0 63193.0 87609.0 108534.0 130619.0 106688.0 123948.0 120206.0 102488.0 True False 56983.70365962505 27932.5368711603 64699.76078078708 82700.55176221016 87267.5418178382 123769.10969839201 96581.74028576908 120694.49633376165 121963.78534259027 121068.26310543861 0.47067416511953936 0.23071725119929898 0.5344072766984351 0.6830902636323944 0.7208127016891016 1.0223084607284836 0.7977461459214611 0.9969127601066561 1.007396837240258 1.0 16.885461200235845 -6.0140317815769135 0.9019878188508801 0.9724770160403231 0.3152023844256012 0.8619144627178162 0.09586294115397832 0.21484482481666514 0.35434874543550554 0.0423635757107367 0.09445843797614122 9.682070004883188e-07 6.0140317815769135 -0.6572746316147219 down ESQLAHIKDEPPPLS(ph)PAPLTPATPSSLDPFFSR ddPTM_PC-9_Lapatinib_30min_R1 1 ESQLAHIKDEPPPLSPAPLTPATPSSLDPFFSR 33 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 ESQLAHIKDEPPPLS(0.996)PAPLT(0.004)PATPSSLDPFFSR 67.788 1.1180999999999998e-05 96081000.0 186280.0 144980.0 259620.0 176200.0 235720.0 337920.0 240760.0 262780.0 402000.0 213220.0 True False 183623.613040432 144644.307717545 238275.04576218087 189158.3357859689 221855.41304335097 323467.9493299942 253225.37475227274 274989.71812555427 356722.52675233205 250074.79290220854 0.7342747779950689 0.5784041887584727 0.9528151278140138 0.7564070476305025 0.8871562402137319 1.2934848233843623 1.0125985582693104 1.09962989445757 1.4264633496740633 1.0 17.93200011817025 -6.5915208157400205 4.637139955514271 1.1617910365894264 0.7628396982614318 0.6430632736446158 0.14561457174116182 0.1367331053688519 5.716399423600646 0.048865209198530046 0.049211739085640374 2.5614104927083837e-07 6.5915208157400205 -0.39895133832799456 ESQMTPSHGGS(ph)PVGPPQLPIMSSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESQMTPSHGGSPVGPPQLPIMSSLR 25 0 A0A5F9ZH11;P55201-3;P55201;P55201-2 A0A5F9ZH11 BRPF1 Peregrin 1 ES(0.035)QMT(0.028)PS(0.072)HGGS(0.864)PVGPPQLPIMSSLR 42.845 0.034707 9319900.0 7505.2 5582.4 8315.3 9688.6 10483.0 11364.0 8896.2 9832.8 9657.1 8144.0 True False 8775.682125543106 6136.583779203668 8513.568287950857 9145.779152865007 8428.931402845157 10768.051834821335 8053.487533089562 9574.699418712773 9798.316818061732 9620.442732131472 0.9121910882784077 0.6378691656994114 0.8849455815080373 0.9506609422785576 0.8761479733872571 1.119288595612855 0.8371223401384209 0.9952451966409072 1.0184891788125483 1.0 13.231887572914493 -5.523596606410557 4.475965038655675 0.9656595837248875 0.770294988419996 0.39887316517806193 0.09558680218975144 0.17422715912334155 8.840625368646801 0.02462806185445013 0.048232464430695225 2.995045287028812e-06 5.523596606410557 -0.19536459530489148 ESQQQHGLR ddPTM_PC-9_AZD4547_30min_R2 2 ESQQQHGLR 9 0 Q9UHB9-4;Q9UHB9-2;Q9UHB9 Q9UHB9-4 SRP68 Signal recognition particle subunit SRP68 0 ; 93.096 0.0054727 1445620.0 6315.5 3593.95 10348.7 12384.5 10397.6 9716.5 7228.799999999999 8908.400000000001 11069.8 14840.0 False True 8323.697629439455 4755.624053977225 10211.469476279537 9529.444863617633 8954.07271564026 9108.925718986746 7872.149195958823 7531.811474666966 11654.927028555398 14320.456116944459 0.5812452872636207 0.3320860742941146 0.7130687313930576 0.6654428312756089 0.6252644917535477 0.6360779045444475 0.5497135797681908 0.5259477361028373 0.8138656292354323 1.0 13.805789823769931 -14.522878743916339 0.1722033450721021 2.6143538577581418 0.5059727135077386 0.5725639532133657 0.11042759437121198 101.46298488745312 0.9586823177862991 55.675033271582535 0.39736356221725805 3.0000000094221703e-15 14.522878743916339 -2.1083811442504032 ESQQQHGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESQQQHGLR 9 0 Q9UHB9-4;Q9UHB9-2;Q9UHB9 Q9UHB9-4 SRP68 Signal recognition particle subunit SRP68 0 ; 107.15 0.0021162 1259820.0 5521.299999999999 4532.4 8174.8 6693.5 14681.7 11941.6 7642.6 9254.099999999999 11089.5 10085.0 False True 6455.9470393542015 4982.346718411921 8369.718235101638 6318.484895619792 11804.926278465296 11315.361474014653 6918.637600367606 9011.189680529436 11251.66295822717 11913.330667183927 0.5419094978314959 0.418216102415098 0.702550652619472 0.530370982904427 0.9909005808915186 0.9498067156973641 0.5807475502569117 0.7563954978057787 0.9444598888890606 1.0 13.540289190339122 -6.245999876871212 24.854061564217623 0.8476940223362522 0.5499934331100393 0.5717833096425877 0.135713331958397 638.5152537839762 1027862.9828070543 0.0421175029411692 0.05416883880499933 5.675447663157012e-07 6.245999876871212 -0.2977005892262129 ESQQQHGLR ddPTM_PC-9_Lapatinib_30min_R1 1 ESQQQHGLR 9 0 Q9UHB9-4;Q9UHB9-2;Q9UHB9 Q9UHB9-4 SRP68 Signal recognition particle subunit SRP68 0 108.43 0.0020444000000000005 460320.0 3614.4 2677.6 4511.4 3838.9 4184.9 4561.0 3507.3 4932.3 6895.5 4375.6 False True 3562.857993200219 2671.400181711253 4140.490106507604 4121.225512194989 3938.75240982996 4365.936662210299 3688.8908326492997 5161.472664246407 6118.856177165931 5131.916629879488 0.6942548467089741 0.5205462937877042 0.8068116466273993 0.803057767579472 0.7675012463954336 0.8507419307614168 0.7188134762695717 1.0057592584795385 1.1923140258242306 1.0 12.325282018098958 -7.856538519398829 3.8917664030739987 1.0977018501616413 0.739076878287669 0.7151626372908181 0.0958965115677974 0.1256233556803644 3.5405584362988676 0.060773671402139795 0.02740601940378561 1.3914303775763554e-08 7.856538519398829 -0.35862497187397235 ESQSPDTTIQR ddPTM_PC-9_Lapatinib_30min_R1 1 ESQSPDTTIQR 11 0 Q92973-3;Q92973-2;Q92973;E7EW37 Q92973-3 TNPO1 Transportin-1 0 91.469 0.033062 0.0 7603.5 9706.7 9291.3 8084.8 11444.0 10097.0 7421.0 7508.3 8166.4 6653.4 False True 7495.072695688871 9684.224732527871 8527.40517945518 8679.383162102176 10770.886419769664 9665.174847256596 7805.22306876813 7857.163028396748 7246.614035995629 7803.431324901769 0.9604842259290621 1.2410213314268872 1.0927763472772696 1.112252136365336 1.380275672497861 1.2385801123684859 1.0002296097436834 1.0068856508448423 0.9286445583074124 1.0 12.92989293003117 -7.320377377175975 7.000204025283398 0.98312116228455 1.1772470046835535 0.4289057558683721 0.10556916541022118 0.26471664587116445 26.81125391890236 0.045962352818563715 0.03093960637294746 4.782143706710662e-08 7.320377377175975 0.19412584239900343 ESRPGLVTVTSSQS(ph)TPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESRPGLVTVTSSQSTPAK 18 1 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 ESRPGLVTVTS(0.002)S(0.054)QS(0.706)T(0.239)PAK 87.79299999999999 0.00075797 5321700.0 12130.0 14077.0 14362.0 11790.0 18093.0 8853.6 17284.0 13632.0 10049.0 8835.5 True False 14183.36942157943 15474.471528348022 14704.444548188307 11129.444523695734 14547.806531687254 8389.301630127962 15646.734394676374 13274.174444297909 10195.947614159772 10437.306208220478 1.3589109238175394 1.4826116259921784 1.408835216179344 1.0663138842214024 1.3938277024228076 0.8037803493319478 1.4991161591439104 1.2718008056372916 0.9768753939718074 1.0 13.349461790545979 -1.5228787482048822 0.15425451944602667 0.9906017900569764 2.706505955597028 0.25856899112463094 0.1998535712970796 98.00434477398021 0.987820241110505 0.6566671599668511 37.85915019584787 0.029999999797979612 1.5228787482048822 1.7159041655400518 ESRPGLVTVTSSQS(ph)TPAK ddPTM_PC-9_Lapatinib_30min_R1 1 ESRPGLVTVTSSQSTPAK 18 1 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 ESRPGLVTVTS(0.001)S(0.017)QS(0.563)T(0.42)PAK 74.047 0.0030503 10255000.0 16928.0 24030.0 24047.0 21618.0 25430.0 21744.0 23112.0 22106.0 25708.0 19884.0 True False 16686.603615785 23974.360011398796 22069.94848410436 23207.859835533956 23934.25739730363 20814.05980773967 24308.626272115467 23133.12546192062 22812.494322758568 23320.922906235428 0.7155207228665647 1.0280193501685413 0.946358279766167 0.9951518612210993 1.026299752095326 0.8925058365582313 1.0423526705976096 0.9919472550434701 0.9781986079401292 1.0 14.509337262680601 -4.756209590985487 24.99389181960345 0.9874098972814335 0.7155202979876909 0.7964387221397873 0.04146827079456935 67.79321282842139 323957.69217747875 0.00978112746893076 0.080641477942893 1.753034281429336e-05 4.756209590985487 -0.27188959929374257 ESRPGLVTVTSSQST(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 2 ESRPGLVTVTSSQSTPAK 18 1 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 ESRPGLVTVTSS(0.001)QS(0.16)T(0.839)PAK;ESRPGLVTVT(0.001)S(0.002)S(0.002)QS(0.254)T(0.739)PAK 83.25200000000001 0.011623999999999999 8453200.0 34258.0 42423.0 41304.0 43128.0 44376.0 44284.0 43167.0 50062.0 43125.0 50004.0 True False 45151.331389333674 56135.40512301944 40756.281972445846 33185.50592095775 38215.15838551708 41514.9144794534 47008.77937444037 42326.06821031584 45404.49945856759 48253.37518003308 0.9357134339489063 1.1633467071179695 0.8446306982751856 0.6877343977937878 0.7919686082670183 0.8603525520144752 0.9742070725426122 0.87716285238903 0.940960073552651 1.0 15.558342237685471 -5.281452497143129 24.749771802900014 0.8615169259122615 1.0495300747562404 0.33164280535351187 0.09983232972045719 682.5814205915318 844132.2283082583 0.027156616260861743 0.056652125464828056 5.230551744989109e-06 5.281452497143129 0.1880131488439789 ESRPGLVTVTSSQST(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESRPGLVTVTSSQSTPAK 18 1 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 ESRPGLVTVTSSQS(0.056)T(0.944)PAK 88.319 0.0011197000000000002 5614300.0 35611.0 46282.0 40621.0 38192.0 50180.0 35554.0 48731.0 36806.0 33637.0 30917.0 True False 41639.2389506896 50876.57109291779 41589.55869600035 36052.226060134635 40347.589220144015 33689.48565076012 44114.84689811242 35839.881499180534 34128.87749004799 36522.00736116264 1.1401136454226939 1.3930387393497907 1.1387533627252515 0.9871370350380146 1.104747305402755 0.9224434275369373 1.2078976509112687 0.9813228814277203 0.9344743062053184 1.0 15.156478441980193 -5.518418886698187 5.248651682404587 1.027822539176035 1.2684755496438245 0.5074366941432015 0.09744599236108673 0.12707990694153956 10.998456963729208 0.02512516302078057 0.04856482303609292 3.0309663393575e-06 5.518418886698187 0.24065301046778953 ESRPGLVTVTSSQST(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 2 ESRPGLVTVTSSQSTPAK 18 1 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 ESRPGLVTVTSS(0.001)QS(0.061)T(0.938)PAK;ESRPGLVTVTSSQS(0.002)T(0.997)PAK 127.07 3.1248e-05 8412300.0 31618.0 50142.0 42179.0 54399.0 53312.0 48460.0 49561.0 54649.0 55854.0 43990.0 True False 31167.121521968933 50025.899279715326 38711.20543564843 58399.68392974424 50176.29297542476 46387.478765777465 52127.026076164555 57188.19204598296 49563.134351305314 51593.61288700946 0.6040887578511946 0.9696141921534465 0.7503100339266096 1.131916930447188 0.9725291594777701 0.8990934375417072 1.010338744648941 1.108435499006935 0.9606447693409083 1.0 15.654904855535479 -4.222637888335472 0.9099238614483398 1.0028522319265756 4.487889834940741e-16 0.5446323814876111 0.10158035616698005 4.104193753337845 1.3113036682628378 0.03335809734329661 5.203491109943597 5.9891075448084825e-05 4.222637888335472 -1.0028522319265751 ESRPSEER ddPTM_PC-9_Lapatinib_30min_R1 1 ESRPSEER 8 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 98.62899999999999 0.007061399999999999 2786900.0 7007.4 14032.0 12645.0 11581.0 15992.0 9719.8 14415.0 14411.0 13194.0 10759.0 False True 6907.473191000222 13999.509766123501 11605.376911111554 12432.705373083474 15051.382001481697 9304.106811960457 15161.338166863308 15080.587669942 11707.952781020565 12618.678814533641 0.5474006663078307 1.109427537691147 0.9196982569795651 0.9852620512667324 1.192785886914419 0.7373281267167522 1.2014996490283232 1.195100366020319 0.9278271483965388 1.0 13.623273246486368 -4.755878300314122 24.99850304879651 1.032451929967988 0.5473998952518496 0.5106634796350997 0.14166923918161436 145.2811217606805 653008.5457184325 0.03432899460931795 0.2925945703215775 1.7543720499140094e-05 4.755878300314122 -0.48505203471613834 ESRQES(ph)DPEDDDVKKPALQSSVVATSK ddPTM_PC-9_AZD4547_30min_R2 1 ESRQESDPEDDDVKKPALQSSVVATSK 27 3 Q9H307 Q9H307 PNN Pinin 1 ES(0.35)RQES(0.639)DPEDDDVKKPALQS(0.005)S(0.005)VVATSK 49.025 0.019226 10520000.0 10917.0 3820.4 10876.0 33479.0 19923.0 9804.2 8461.2 13083.0 8721.1 17334.0 True False 14388.378912293649 5055.269588006117 10731.77713374784 25760.933795393823 17157.035346012643 9191.141824122878 9214.230408483674 11061.322967431632 9182.07954152148 16727.141936058964 0.8601815520723474 0.30221956669766714 0.6415786495248886 1.5400678665768102 1.0257003504601674 0.5494747315026597 0.5508550380995101 0.6612799131922569 0.5489329603718808 1.0 14.029903341547536 -6.7730669003439905 24.977319438263 0.6339851746366922 0.8662839054608147 0.09706774196438384 0.3168746113445834 570.0945644694674 1224624.6637238103 0.1221173261026357 0.10858403940124078 1.6862932424712703e-07 6.7730669003439905 0.23229873082412245 ESRS(ph)PQQSAALPR ddPTM_PC-9_AZD4547_30min_R2 2 ESRSPQQSAALPR 13 1 E5RJN3;A0A0A6YYG7;Q6IBW4-2;Q6IBW4;Q6IBW4-4 E5RJN3 NCAPH2 Condensin-2 complex subunit H2 1 ESRS(0.999)PQQS(0.001)AALPR;ES(0.016)RS(0.978)PQQS(0.006)AALPR 145.61 2.7736e-07 7820200.0 78894.0 72809.0 86153.0 109989.0 111101.0 102077.0 83995.0 103667.0 79510.0 91256.0 True False 103980.65090285748 96343.0853924032 85010.55492862989 84632.73536311029 95676.5438928549 95694.10905336395 91470.39228012422 87647.64718067218 83712.73627711783 88061.1552161648 1.1807777293815291 1.0940474850222965 0.9653581618359813 0.9610677392927821 1.0864784098959015 1.0866778753749307 1.0387144258508842 0.9953043083016845 0.9506204645127259 1.0 16.42621814971229 -4.968263511019603 3.555953750245569 1.0152219895774381 1.1762356175791173 0.5768896193499624 0.046133189183008405 0.19049049845639232 4.888831399909344 0.013171027858218649 0.06396108012099941 1.075812259427529e-05 4.968263511019603 0.16101362800167918 ESRS(ph)PQQSAALPR ddPTM_PC-9_Lapatinib_30min_R1 1 ESRSPQQSAALPR 13 1 E5RJN3;A0A0A6YYG7;Q6IBW4-2;Q6IBW4;Q6IBW4-4 E5RJN3 NCAPH2 Condensin-2 complex subunit H2 1 ES(0.036)RS(0.931)PQQS(0.034)AALPR 123.1 0.00082886 4999500.0 29963.0 23461.0 30217.0 28365.0 27327.0 26052.0 22754.0 25659.0 25019.0 16696.0 True False 29535.72212545876 23406.67749593955 27732.674900993126 30451.05672286614 25719.679586949136 24937.816690178173 23932.090783822936 26851.2108127848 22201.09675825023 19581.8813539784 1.508318919492282 1.1953232211359548 1.4162415959771277 1.5550628753390683 1.3134427240171045 1.2735148497420359 1.2221548252288188 1.3712273262920935 1.1337570868153428 1.0 14.257231759897827 -8.542967657781224 0.43542578588500463 0.9795351205051762 1.40525358620137 0.5670981959449245 0.10661336984659452 1.0165812283427358 0.48981864695395616 0.15379693278299952 0.07727345018024939 2.864391275218337e-09 8.542967657781224 0.42571846569619376 ESS(ph)NPSDRWR ddPTM_PC-9_Lapatinib_30min_R1 2 ESSNPSDRWR 10 1 Q9Y388 Q9Y388 RBMX2 RNA-binding motif protein, X-linked 2 1 ES(0.001)S(0.775)NPS(0.225)DRWR;ESS(0.999)NPS(0.001)DRWR 132.03 0.00077287 17346100.0 90275.0 59319.0 85411.0 58407.0 59767.0 65246.0 51904.0 52670.0 73990.0 49932.0 True False 88987.66194559236 59181.65050004847 78388.83727599458 62702.445620040286 56251.62256644303 62455.580675854646 54591.33515177752 55117.240481288296 65656.46705075877 58562.67966979216 1.5195285196536872 1.010569373425984 1.3385459428768107 1.070689489852417 0.9605370328615407 1.0664740928525258 0.9321864275950621 0.9411666404623029 1.1211315366879588 1.0 15.837693948503908 -1.5228787462214375 0.5473438606722061 0.9988823054575062 20.33278872975751 0.5770937472000853 0.11742087912592157 97.27110980451175 0.8984512193131656 0.05689310410726393 2208.619138303379 0.029999999934991122 1.5228787462214375 19.333906424300004 ESS(ph)PEKEAEEGCPEK ddPTM_PC-9_AZD4547_30min_R2 1 ESSPEKEAEEGCPEK 15 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 ES(0.201)S(0.799)PEKEAEEGCPEK 92.38 0.029886000000000003 0.0 5635.8 11494.0 4559.3 3471.3 4917.2 9517.1 8993.4 10023.0 8117.3 6836.9 True False 7427.867168077727 15209.210722579399 4498.840703006302 2671.045416050378 4234.531657050313 8921.994232508492 9793.795177475664 8474.175655626936 8546.363906203604 6597.5422119904 1.1258536784468451 2.3052843367850104 0.6818964636300607 0.40485461558639363 0.641834719807394 1.3523209016069082 1.4844611618666692 1.284444325377098 1.2953860136993753 1.0 12.687712960806188 ESS(ph)PEKEAEEGCPEK ddPTM_PC-9_Lapatinib_30min_R1 2 ESSPEKEAEEGCPEK 15 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 ES(0.026)S(0.974)PEKEAEEGCPEK;ES(0.212)S(0.788)PEKEAEEGCPEK 201.4 1.2269e-09 32172400.0 40218.0 77558.0 57598.0 56823.0 71520.0 53338.0 70803.0 81841.0 56201.0 69177.0 True False 39644.483944922096 77378.41921614937 52862.51477470965 61001.952975971224 67313.33421373014 51056.858076950826 74468.83289826039 85643.63163525947 49871.05155723331 81134.1522774415 0.4886288058986083 0.9537095913882325 0.6515445504865096 0.7518652905544952 0.8296547424757638 0.6292893515712081 0.9178481663752548 1.0555805321339604 0.6146739709154443 1.0 16.30802170397733 -7.281641945704934 24.11503671555276 0.9016574106519534 0.7318568699485325 0.23235277280304023 0.1585240322028937 818.8365234516309 977408.7598805751 0.06232465291729001 0.04208861628131722 5.22827056379096e-08 7.281641945704934 -0.16980054070342088 ESS(ph)PEKEAEEGCPEKESEEGCPK ddPTM_PC-9_AZD4547_30min_R2 1 ESSPEKEAEEGCPEKESEEGCPK 23 2 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 ES(0.329)S(0.671)PEKEAEEGCPEKESEEGCPK 57.045 0.0025754000000000003 14321000.0 28793.0 40385.0 23479.0 30419.0 22922.0 31210.0 33413.0 23015.0 26602.0 34603.0 True False 37948.57506839523 53438.66147828165 23167.653119093917 23406.369518865093 19739.675962520785 29258.433766230275 36386.692270442116 19458.56058208659 28008.127410940637 33391.55950233348 1.1364720795907508 1.6003643517921715 0.6938176432722438 0.7009666474915435 0.5911576535124491 0.8762224407094741 1.0896973011368136 0.5827388978561118 0.8387786562943657 1.0 15.027195853415982 -5.270023903694981 24.998341029203154 0.7843185814601619 1.368418222993538 0.5972555166348072 0.18758156951857427 354.1973855728408 1031433.1377031964 0.048375290410877285 0.10327391481419332 5.370022387969478e-06 5.270023903694981 0.5840996415333761 ESS(ph)PEKEAEEGCPEKESEEGCPK ddPTM_PC-9_Lapatinib_30min_R1 3 ESSPEKEAEEGCPEKESEEGCPK 23 2 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 ES(0.055)S(0.945)PEKEAEEGCPEKESEEGCPK;ES(0.195)S(0.805)PEKEAEEGCPEKESEEGCPK;ES(0.262)S(0.738)PEKEAEEGCPEKESEEGCPK 85.166 9.6196e-05 60747100.0 73129.1 134861.1 104194.8 125681.4 132897.0 113289.7 134038.8 122887.5 106072.4 120903.0 True False 72086.26562376559 134548.83740879147 95628.30574755918 134924.42941685978 125080.25974555497 108444.56362218944 140978.67320711468 128597.30187287473 94125.4093201096 141800.92245687876 0.5083624589655742 0.9488572787649345 0.6743842288941347 0.9515060063018271 0.8820835406313489 0.7647662775618904 0.9942013829281391 0.9068862151583026 0.6637855924296462 1.0 17.11350739220208 -4.75251856450906 24.996089402646113 0.8604137266777638 0.5083617834774543 0.4522035602428194 0.1177076358266243 314.21031447615604 880351.3770411757 0.027762227836790596 0.32781241819411183 1.7679966406949082e-05 4.75251856450906 -0.3520519432003095 ESS(ph)PIPS(ph)PTSDRK ddPTM_PC-9_Lapatinib_30min_R1 1 ESSPIPSPTSDRK 13 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 2 ES(0.184)S(0.816)PIPS(0.771)PT(0.136)S(0.093)DRK 178.67 0.00069885 7005400.0 41356.0 43383.0 41866.0 41697.0 42358.0 44208.0 46281.0 41688.0 43363.0 41161.0 True False 40766.25585623843 43282.549328943554 38423.939087433464 44763.5364771144 39866.585719032104 42317.326893881356 48677.2037253278 43624.97666952625 38479.00230736655 48275.62400641502 0.8444480355307531 0.8965715145016464 0.795928377483584 0.9272492567090604 0.8258119193598513 0.8765775226076434 1.008318478055497 0.9036646872493916 0.7970689783782668 1.0 15.559007286993467 -7.017392473561418 24.886554528760406 0.9225512245437559 0.8596082893617979 0.20755100364350354 0.06389488990768402 1248.9193474138613 1787051.500987611 0.02364192545298755 0.018743924321067702 9.60743658287314e-08 7.017392473561418 -0.06294293518195804 ESS(ph)PIPSPTS(ph)DR ddPTM_PC-9_AZD4547_30min_R2 1 ESSPIPSPTSDR 12 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 2 ES(0.142)S(0.858)PIPS(0.039)PT(0.187)S(0.774)DR 139.66 0.00088547 9364500.0 39184.0 38984.0 43510.0 58596.0 56793.0 56548.0 44528.0 55360.0 49604.0 42129.0 True False 51643.69692216857 51584.815626329866 42933.02897107105 45087.597499175514 48908.27226853866 53012.04462072379 48490.90573783398 46805.384046244384 52225.966171426946 40654.07653306958 1.2703202563255769 1.2688719072088332 1.0560571689815088 1.1090547700056486 1.2030348845522245 1.3039785709460592 1.192768594765389 1.1513085042817564 1.284642786780419 1.0 15.31111240341603 -10.696352015106909 4.469718079461522 0.9999595406659861 1.2001525509519553 0.38800207740927506 0.07686036399604783 3.29023961770518e-05 6.084152465201526e-06 0.0790152257563388 0.019160137747474527 2.0120926975809135e-11 10.696352015106909 0.20019301028596914 ESS(ph)PIPSPTSDR ddPTM_PC-9_AZD4547_30min_R2 1 ESSPIPSPTSDR 12 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 ES(0.308)S(0.692)PIPSPTSDR 76.24 0.018871000000000002 4214300.0 27364.0 26938.0 27900.0 31138.0 30833.0 31568.0 23626.0 24956.0 28970.0 21722.0 True False 36065.182793441716 35645.181698698776 27530.027770463847 23959.615177304353 26552.370166320718 29594.047969636566 25728.668230373387 21099.623631829385 30501.295056572806 20961.519391662212 1.720542395785834 1.7005056280832977 1.3133603178314626 1.1430285529222983 1.2667197291472276 1.411827426088592 1.2274238212239226 1.0065884651578314 1.455108977868522 1.0 14.355455673684846 -5.3028676958538075 3.58496246028136 1.2268904264648142 1.7234968190142552 0.6597297871395765 0.139889138101904 0.13038595340903034 3.4832613660753444 0.036366618505393584 0.09187690099191319 4.97888739477326e-06 5.3028676958538075 0.49660639254944106 ESS(ph)PIPSPTSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESSPIPSPTSDR 12 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 ES(0.058)S(0.918)PIPS(0.02)PT(0.003)SDR 89.35600000000001 0.0075358000000000005 4513100.0 24411.0 27457.0 23398.0 22002.0 21374.0 20399.0 22931.0 13408.0 15549.0 15467.0 True False 28543.300160772895 30182.74950300856 23955.897057409144 20769.29927144644 17185.918134542808 19329.240529612856 20758.809673936816 13056.054206950299 15776.374709182037 18271.04466329538 1.562215006682864 1.6519443775233362 1.3111399757855138 1.1367329922393434 0.9406094972263694 1.0579165497002634 1.1361588817983186 0.7145762296328106 0.8634632009233236 1.0 14.157271503250431 -5.63530889484762 1.255340972054583 0.941174957950635 1.655890211720722 0.8401675396802231 0.11259306360718442 0.20473296631802515 0.6102409255166701 0.04090817658621308 0.1271276825501897 2.3157469735932138e-06 5.63530889484762 0.7147152537700869 ESS(ph)PIPSPTSDR ddPTM_PC-9_Lapatinib_30min_R1 1 ESSPIPSPTSDR 12 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 ES(0.095)S(0.905)PIPSPTSDR 128.68 0.00019779 4390900.0 21016.0 26187.0 24894.0 18649.0 25868.0 21591.0 21468.0 19417.0 25656.0 20361.0 True False 20716.307986137617 26126.365610424487 22847.311413618914 20020.509671240292 24346.49509844477 20667.603261079257 22579.507996269258 20319.184705243482 22766.351110342857 23880.371720672887 0.8675035811190416 1.0940518814373092 0.9567401915205672 0.8383667518001334 1.0195191005912345 0.865464051515899 0.9455258176204397 0.8508738868437907 0.9533499468366466 1.0 14.543537673245865 -5.524061341965132 24.99995263419961 0.9190687856092361 0.9919323122070016 0.07525871411049567 0.07646113086818945 68.62187901716314 1450651.7924171723 0.019130545996601817 0.03347730846394252 2.991842023753555e-06 5.524061341965132 0.07286352659776552 ESS(ph)PIPSPTSDRK ddPTM_PC-9_AZD4547_30min_R2 2 ESSPIPSPTSDRK 13 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 ES(0.001)S(0.977)PIPS(0.007)PT(0.007)S(0.007)DRK;ES(0.002)S(0.939)PIPS(0.011)PT(0.011)S(0.037)DRK 140.01 1.9985999999999998e-05 0.0 51199.0 40234.0 41034.0 53154.0 48903.0 42238.0 37823.0 49428.0 34794.0 43138.0 True False 67479.21699464344 53238.85368124759 40489.86234886071 40900.16652111364 42113.66257722512 39596.8511828912 41189.17372714012 41790.038342445194 36633.13980664115 41627.751750185285 1.621015167948461 1.2789269524028672 0.9726651247429065 0.9825216304392801 1.011672761718093 0.9512128212092299 0.9894642875340196 1.0038985192674785 0.8800172545104623 1.0 15.345258022427148 -4.900122565456937 1.9187708099843062 0.9721189351554198 1.734766789778884 0.9660687030967188 0.0383635942385141 0.09414367495999933 0.4526290322576849 0.010336034752830136 0.11915233144035756 1.2585701712750207e-05 4.900122565456937 0.7626478546234643 ESS(ph)PIPSPTSDRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESSPIPSPTSDRK 13 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 ES(0.161)S(0.839)PIPSPTSDRK;ES(0.259)S(0.741)PIPSPTSDRK 115.83 0.0002298 13481000.0 103233.0 80529.0 81063.0 74476.0 90984.0 65416.0 75456.0 63746.0 57093.0 60866.0 True False 120708.30795530984 88523.38692237964 82995.84935313964 70303.35117444968 73156.3383341088 61985.469801713516 68308.26142586781 62072.73504447001 57927.877115655676 71900.52398500919 1.6788237590657442 1.2311925145474074 1.1543149444980922 0.9777863536725753 1.0174659971791227 0.8621003904594228 0.9500384369953918 0.8633140845734558 0.8056669674303525 1.0 16.133714664091904 -1.5228787453091905 0.5574275165808851 0.8888662268984322 37.70332022827364 0.9298307856059291 0.06421105395943118 30.663469415896408 0.27425051012898355 0.029823011792061028 1355.4134409027083 0.029999999998006906 1.5228787453091905 36.81445400137521 ESS(ph)PIPSPTSDRK ddPTM_PC-9_Lapatinib_30min_R1 1 ESSPIPSPTSDRK 13 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 ES(0.331)S(0.552)PIPS(0.088)PT(0.014)S(0.014)DRK 83.85600000000001 0.0040907 17290000.0 60361.0 60571.0 68590.0 52381.0 71903.0 68300.0 51945.0 50582.0 65715.0 52343.0 True False 59500.24107114828 60430.75157097112 62950.794965056615 56233.27347789361 67673.80690673701 65378.96821507627 54634.457931163 52932.224378669554 58313.484690371915 61390.4178073366 0.9692105575479171 0.984367817150598 1.02541727542264 0.9159943112681231 1.1023513004768881 1.0649702437317996 0.8899509057362008 0.8622229049619494 0.9498792608543386 1.0 15.90572586803315 -7.273163991315759 24.979899745273173 0.914031839202347 1.0097756926105752 0.32448813529184917 0.05906522001106076 834.0555760563244 1776992.5714037607 0.02505045818197352 0.01706085497095754 5.3313354413751325e-08 7.273163991315759 0.09574385340822822 ESS(ph)PLPK ddPTM_PC-9_AZD4547_30min_R2 1 ESSPLPK 7 0 Q9HCE3 Q9HCE3 ZNF532 Zinc finger protein 532 1 ES(0.07)S(0.93)PLPK 77.282 0.030021 4684600.0 44318.0 49858.0 57423.0 66853.0 62399.0 64073.0 53413.0 87042.0 50900.0 53794.0 True False 58410.202128334684 65973.62347367006 56661.53350047831 51441.07371855382 53735.975935142415 60066.50518114936 58166.65352530826 73591.65892617781 53590.47008559051 51910.68843361925 1.1252056925237406 1.2709063482761123 1.0915195927893386 0.9909534099963642 1.0351620746439771 1.15711247516895 1.120514007431992 1.4176590822963768 1.0323590709863013 1.0 15.663744000262867 -7.558268340146742 24.999411955413773 1.1888225953503955 1.1116140121036864 0.0 0.1268611455035006 530.7147922358185 374894.478169659 0.059258755440027976 0.03421327044174652 2.7652325465752275e-08 7.558268340146742 -0.0772085832467091 ESS(ph)PLPK ddPTM_PC-9_Lapatinib_30min_R1 1 ESSPLPK 7 0 Q9HCE3 Q9HCE3 ZNF532 Zinc finger protein 532 1 ES(0.036)S(0.964)PLPK 90.709 0.015746 4085000.0 40327.0 47130.0 41766.0 37384.0 56143.0 49228.0 51235.0 46720.0 49833.0 44311.0 True False 39751.92958493392 47020.87338065858 38332.160701422334 40133.34406936816 52840.7791213849 47122.633196072864 53887.697605219626 48890.78175974537 44220.282775246116 51970.097309303856 0.7649000414285813 0.9047678533447878 0.7375810838545416 0.7722391557304888 1.0167535151396603 0.9067258988494681 1.0368981471114636 0.9407483204960785 0.8508793530261421 1.0 15.665394139873692 -6.254013257803382 24.996601465638467 0.9570194042656948 0.7986295176591008 0.6010958768654253 0.06533176729699862 418.67038140218324 1409259.3189063566 0.01932963203677341 0.024460326169278457 5.571687398593714e-07 6.254013257803382 -0.15838988660659392 ESS(ph)PLSSR ddPTM_PC-9_AZD4547_30min_R2 1 ESSPLSSR 8 0 Q14693;Q14693-2;Q14693-4;Q14693-3;Q14693-5;Q14693-7;A0A0A0MS66;Q14693-6 Q14693 LPIN1 Phosphatidate phosphatase LPIN1 1 ES(0.125)S(0.875)PLSSR 137.05 0.0033040999999999995 20403000.0 58698.0 60120.0 72128.0 111410.0 89648.0 74035.0 60260.0 92542.0 68536.0 69925.0 True False 77362.74300575365 79552.61428932259 71171.53559240194 85726.1457673415 77201.92263712003 69405.57974632664 65623.02326091172 78241.76030360446 72158.67304098282 67476.94703351341 1.1465062722433237 1.1789598935146195 1.054753344976523 1.270450865608433 1.1441229342930495 1.0285820979994151 0.9725250792440134 1.1595331997570155 1.0693825997365316 1.0 16.04210708051268 -6.692210540814606 6.032487423978531 1.0515529067039684 1.1617276030790922 0.4128219681838672 0.06733442447034026 0.22447801948726037 14.560789975604953 0.02274648598069147 0.022560422162998837 2.0313719871418986e-07 6.692210540814606 0.11017469637512378 ESS(ph)PLSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESSPLSSR 8 0 Q14693;Q14693-2;Q14693-4;Q14693-3;Q14693-5;Q14693-7;A0A0A0MS66;Q14693-6 Q14693 LPIN1 Phosphatidate phosphatase LPIN1 1 ES(0.045)S(0.955)PLSSR;ES(0.147)S(0.852)PLSSR 106.88 0.003819 18246600.0 80511.0 89456.0 104552.0 77942.0 97379.0 90007.0 87542.0 77861.0 74569.0 57612.0 True False 94139.92213526645 98336.60048589177 107044.91619566828 73575.1624313733 78298.28399100044 85286.87447173207 79249.38801080555 75817.2312505488 75659.43055431182 68056.59954365884 1.3832592689982248 1.4449238008550231 1.5728807626804528 1.0810878434232416 1.150487748668246 1.253175666189726 1.1644629402908449 1.1140320227417688 1.1117133542027133 1.0 16.054447448218546 -5.766942097550119 24.999555307739566 1.137793186091241 1.464811546832739 0.8126765578373251 0.07507204280222393 54.71381429039657 248573.28431253345 0.02131432023442565 0.032650534595990675 1.7102433186248437e-06 5.766942097550119 0.32701836074149804 ESS(ph)PLSSR ddPTM_PC-9_Lapatinib_30min_R1 4 ESSPLSSR 8 0 Q14693;Q14693-2;Q14693-4;Q14693-3;Q14693-5;Q14693-7;A0A0A0MS66;Q14693-6 Q14693 LPIN1 Phosphatidate phosphatase LPIN1 1 ES(0.131)S(0.868)PLSSR;ES(0.124)S(0.876)PLSSR;ES(0.014)S(0.986)PLSSR;ES(0.002)S(0.998)PLSSR 157.99 3.7163e-05 37551200.0 167925.0 194991.0 218239.0 176302.0 190545.0 196287.0 199148.0 178800.0 192954.0 152543.0 True False 165530.35870632625 194539.5103197112 200296.23184690202 189267.83720623163 179337.51772588378 187892.26257734533 209458.90900135203 187107.7007414912 171221.48862430194 178909.85429922902 0.9252165530774767 1.0873605094683123 1.1195371693272078 1.0578949826300723 1.0023903849697373 1.0502063361087597 1.170751101563301 1.045821100656374 0.9570265947337468 1.0 17.44887332721006 -8.160217765253046 5.639336529650715 0.979599403319136 1.0629226840222086 0.20137286770479046 0.06266544940440813 0.3384872772776942 15.020576072987268 0.04491847196489543 0.01634195408188402 6.914841578976916e-09 8.160217765253046 0.0833232807030726 ESS(ph)PLYS(ph)PTFSDSTSAVK ddPTM_PC-9_AZD4547_30min_R2 8 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 ES(0.082)S(0.918)PLY(0.009)S(0.764)PT(0.191)FS(0.035)DS(0.002)TSAVK;ES(0.09)S(0.91)PLYS(0.954)PT(0.03)FS(0.014)DS(0.001)T(0.001)SAVK;ES(0.005)S(0.995)PLYS(0.984)PT(0.006)FS(0.009)DS(0.001)TSAVK;ES(0.212)S(0.788)PLY(0.009)S(0.774)PT(0.183)FS(0.035)DSTSAVK;ES(0.118)S(0.882)PLY(0.002)S(0.937)PT(0.039)FS(0.016)DS(0.003)T(0.002)S(0.001)AVK;ES(0.017)S(0.983)PLYS(0.934)PT(0.029)FS(0.029)DS(0.007)TSAVK;ES(0.12)S(0.88)PLY(0.001)S(0.749)PT(0.21)FS(0.041)DSTSAVK;ES(0.182)S(0.818)PLY(0.04)S(0.809)PT(0.127)FS(0.023)DSTSAVK 273.52 2.3112999999999994e-90 73038000.0 326966.30000000005 329683.4 400361.7 521548.0 478793.0 450807.0 360062.6 453365.0 394472.1 440094.0 True False 430934.7820784712 436247.11173972744 395052.64226631215 401313.16643627494 412320.8565187692 422617.9670250877 392107.4738663184 383307.8565412854 415323.08987524675 424686.4430141892 1.0147128291167826 1.0272216570971444 0.9302219290600549 0.944963450182154 0.970883020405229 0.9951294042389943 0.9232870046035769 0.9025667356386008 0.9779523144829241 1.0 18.696038529652917 -5.253075729125229 24.89351663878753 0.9525657566989945 1.0209672524530895 0.42787676984935896 0.030056773827896583 533.7018425200813 1588496.8887024233 0.00787241853459213 0.020051870217930586 5.583728212403582e-06 5.253075729125229 0.06840149575409504 ESS(ph)PLYS(ph)PTFSDSTSAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 ES(0.019)S(0.981)PLYS(0.974)PT(0.009)FS(0.015)DS(0.002)TSAVK;ES(0.078)S(0.922)PLY(0.001)S(0.859)PT(0.051)FS(0.051)DS(0.037)T(0.001)SAVK;ES(0.099)S(0.901)PLY(0.002)S(0.818)PT(0.025)FS(0.154)DS(0.001)TSAVK;ES(0.008)S(0.992)PLY(0.001)S(0.818)PT(0.091)FS(0.091)DSTSAVK;ES(0.074)S(0.926)PLY(0.033)S(0.967)PTFSDSTSAVK;ES(0.497)S(0.503)PLYS(0.953)PT(0.016)FS(0.016)DS(0.016)TSAVK;ES(0.081)S(0.919)PLY(0.001)S(0.91)PT(0.041)FS(0.041)DS(0.004)T(0.002)SAVK;ES(0.064)S(0.936)PLYS(0.892)PT(0.098)FS(0.01)DSTSAVK 241.11 2.832699999999999e-67 32988400.0 234579.2 256908.3 252063.5 294822.4 347635.4 334853.2 365859.0 365593.2 342557.5 267887.9 True False 274288.8254096092 282412.4581761953 258073.64979614702 278304.45675511775 279518.73889159906 317292.9087166311 331202.1869302189 355996.7658780155 347566.7553823801 316453.8556705507 0.8667577294275786 0.892428558273612 0.8155174764715734 0.8794471982823651 0.8832843521508439 1.0026514230465053 1.0466049978389966 1.1249563230116921 1.0983173349109703 1.0 18.271635620066093 -6.913943142203999 1.8094034868067201 1.0814401990122606 0.8610650510666455 0.8742668285277386 0.03611955396735545 0.10834465906826904 0.7244095354038684 0.015733879248481675 0.012838121223405791 1.219149199384916e-07 6.913943142203999 -0.22037514794561508 ESS(ph)PLYS(ph)PTFSDSTSAVK ddPTM_PC-9_Lapatinib_30min_R1 5 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 ES(0.071)S(0.929)PLY(0.184)S(0.808)PT(0.005)FS(0.003)DSTSAVK;ES(0.191)S(0.809)PLY(0.036)S(0.796)PT(0.108)FS(0.054)DS(0.003)T(0.002)S(0.001)AVK;ES(0.06)S(0.94)PLYS(0.953)PT(0.009)FS(0.037)DS(0.001)TSAVK;ES(0.055)S(0.945)PLYS(0.769)PT(0.169)FS(0.061)DSTSAVK;ES(0.406)S(0.594)PLY(0.003)S(0.942)PT(0.013)FS(0.011)DS(0.01)T(0.011)S(0.01)AVK 232.73 1.4586999999999997e-96 31981000.0 302050.8 278254.4 289724.5 269910.7 401115.0 410878.5 404545.60000000003 395100.8 456547.6 358601.0 True False 297743.50020266743 277610.11903269944 265904.46997891174 289760.8332737006 377522.2043224323 393306.1843595645 425490.99171117716 413458.6255543846 405126.401628639 420584.70504420216 0.7079275509350144 0.660057571526581 0.632225724782279 0.6889476241016602 0.8976127752500078 0.9351414343948367 1.0116653948851027 0.9830567317252571 0.9632456833780046 1.0 18.682036860507218 -6.368124576761876 2.175069654373288 0.9809533424288858 0.6612306051669012 0.9696094298411243 0.025755062835221033 0.05109445895995945 0.47488112331666343 0.009447435315185788 0.011288582689558298 4.2842560948580096e-07 6.368124576761876 -0.3197227372619845 ESS(ph)PLYSPT(ph)FSDSTSAVK ddPTM_PC-9_AZD4547_30min_R2 1 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 ES(0.147)S(0.853)PLY(0.004)S(0.2)PT(0.711)FS(0.084)DS(0.001)TSAVK 160.64 0.00014669 3980300.0 16528.0 14223.0 16659.0 22211.0 20609.0 22837.0 14539.0 22243.0 15679.0 24162.0 True False 21783.560196243416 18820.30660407576 16438.09077520276 17090.597106529243 17747.79608723457 21408.99877985904 15832.942834224956 18805.85544329144 16507.759930687094 23316.095734340415 0.9342713481897464 0.807180877043528 0.7050104341007833 0.7329956653659586 0.7611821588592663 0.9182068483415702 0.6790563486538562 0.8065610837063856 0.7079984624687458 1.0 14.509038609928675 -10.89264362362104 4.088104354860872 1.0005796261641664 0.781399502828327 0.382958834345689 0.08236056795423291 118993510.355598 545.8570728179664 649299.5494603362 0.019740334319056006 1.2804315786058492e-11 10.89264362362104 -0.21918012333583936 ESS(ph)PLYSPT(ph)FSDSTSAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 ES(0.007)S(0.993)PLYS(0.436)PT(0.519)FS(0.045)DSTSAVK 246.42 4.7091999999999995e-52 9263400.0 66470.0 64989.0 82341.0 83189.0 92901.0 98048.0 108240.0 85862.0 89346.0 82523.0 True False 77722.0581576576 71440.67842266175 84304.3217199814 78528.19003237695 74697.7159454085 92906.19027636065 97986.7236102622 83608.21347830897 90652.51622397466 97483.76664829161 0.7972820586433471 0.7328469229180501 0.86480369623119 0.8055514546918991 0.7662579987795083 0.9530426805475598 1.0051593919609731 0.8576629356142569 0.9299242257537792 1.0 16.572874375582245 -6.76591295532054 24.999978373111567 0.9437619007286651 0.7946349079528165 0.713605006650704 0.04929084496168931 66.9174858344378 373956.6144149697 0.017431482442688485 0.015895011148446124 1.7143008665971385e-07 6.76591295532054 -0.1491269927758485 ESS(ph)PLYSPT(ph)FSDSTSAVK ddPTM_PC-9_Lapatinib_30min_R1 1 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 ES(0.08)S(0.92)PLYS(0.182)PT(0.391)FS(0.391)DS(0.007)T(0.024)S(0.005)AVK 166.67 3.3213999999999997e-06 3702800.0 17680.0 17283.0 18042.0 16690.0 23763.0 21390.0 22458.0 19976.0 25563.0 19377.0 True False 17427.87995788508 17242.982275364353 16558.65640413403 17917.438276207857 22365.307059855524 20475.199562525377 23620.765352162067 20904.157885973324 22683.825749676256 22726.288631770454 0.7668599233366065 0.7587240730217315 0.7286124308474057 0.7884014220940583 0.9841161230606614 0.9009477919725906 1.0393586799360266 0.9198227754949013 0.9981315522836915 1.0 14.472074480347539 -6.198215940037686 4.107673826944949 0.969994679498539 0.7532212842999539 0.8779859751441098 0.039008169914995214 0.07047415539507332 2.393835541633499 0.01120830406131456 0.01449164059128143 6.335546167036803e-07 6.198215940037686 -0.21677339519858507 ESS(ph)PLYSPTFS(ph)DSTSAVK ddPTM_PC-9_AZD4547_30min_R2 1 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 ES(0.015)S(0.985)PLYS(0.047)PT(0.369)FS(0.53)DS(0.045)T(0.008)SAVK 159.04 0.00010525 3514000.0 38356.0 36072.0 44858.0 61463.0 54680.0 53787.0 41759.0 55618.0 43235.0 51039.0 True False 50552.410145638445 47731.56857359351 44263.153610303496 47293.654943883965 47088.62584550375 50423.69038719086 45475.47010209776 47023.516074494575 45520.31383399813 49252.140145062556 1.0264002741149156 0.9691267919121789 0.8987051827582522 0.9602355309757047 0.9560726844927633 1.0237867885269092 0.9233196764274333 0.9547507161312381 0.9242301694896291 1.0 15.587898794668424 -10.718106278582042 5.04561712029629 1.0000035921231092 0.9587023769326714 0.08870933232415001 0.038720108083184615 1.5750840377222053e-06 2.512598307478864e-07 0.03774205613480926 0.0091529970808472 1.913787534279584e-11 10.718106278582042 -0.041301215190437834 ESS(ph)PLYSPTFS(ph)DSTSAVK ddPTM_PC-9_Lapatinib_30min_R1 2 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 ES(0.009)S(0.991)PLYS(0.052)PT(0.405)FS(0.542)DS(0.001)TSAVK;ES(0.012)S(0.988)PLYS(0.405)PT(0.091)FS(0.504)DSTSAVK 217.65 5.0101e-81 26297000.0 282303.0 263495.0 275173.0 253583.0 351269.0 370651.0 358909.0 365448.0 410316.0 309973.0 True False 278277.3074519696 262884.8935165845 252549.33813849767 272232.3397480896 330608.04804142547 354799.12075968186 377491.55186477536 382428.04821351514 364101.8912609694 363551.4200369404 0.7654413986986871 0.7231023701953159 0.6946729519385075 0.748813853403263 0.9093845597077641 0.9759255533196123 1.0383443195639794 1.0519228563999465 1.0015141495636932 1.0 18.471799905117763 -6.458575181589119 1.8260957276616026 1.0237632812126867 0.7228571618330636 0.9672845806138396 0.024399026094974057 0.057650022262526454 0.3845024103547059 0.009597103575906159 0.010946356529904241 3.478762808753043e-07 6.458575181589119 -0.3009061193796231 ESS(ph)PLYSPTFSDS(ph)TSAVK ddPTM_PC-9_AZD4547_30min_R2 1 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 ES(0.063)S(0.937)PLYS(0.141)PT(0.002)FS(0.003)DS(0.588)T(0.228)S(0.038)AVK 228.26 3.7030999999999993e-96 0.0 9538.4 9516.9 10955.0 15427.0 11772.0 14010.0 10118.0 11515.0 9685.4 11952.0 True False 12571.412788954993 12593.051811877147 10809.729542130162 11870.54349477405 10137.66099951116 13133.952485257489 11018.482398836779 9735.62133837616 10197.350470864008 11533.564117905671 1.0899850783712277 1.0918612566887835 0.9372410324878008 1.029217280402094 0.878970359541558 1.138759220566281 0.9553406289848221 0.8441121269063538 0.8841456436725216 1.0 13.493550785051003 -7.520078175343721 24.635704888199417 0.8984225752911308 1.0220621867363913 0.30630978323091385 0.08018488040490664 111.95399180982174 984859.4615928148 0.03651865165121495 0.021594498060009515 3.019408161764917e-08 7.520078175343721 0.12363961144526048 ESS(ph)PLYSPTFSDSTSAVK ddPTM_PC-9_AZD4547_30min_R2 12 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ES(0.097)S(0.897)PLY(0.006)SPTFSDSTSAVK;ES(0.119)S(0.582)PLY(0.101)S(0.151)PT(0.009)FS(0.035)DS(0.001)T(0.001)SAVK;ES(0.002)S(0.998)PLYSPTFSDSTSAVK;ES(0.009)S(0.714)PLY(0.183)S(0.094)PTFSDSTSAVK;ES(0.26)S(0.74)PLYSPTFSDSTSAVK;ES(0.031)S(0.969)PLYSPTFSDSTSAVK;ES(0.002)S(0.998)PLYSPTFSDSTSAVK;ES(0.079)S(0.921)PLYSPTFSDSTSAVK;ES(0.014)S(0.986)PLYSPTFSDSTSAVK;ES(0.144)S(0.856)PLYSPTFSDSTSAVK;ES(0.086)S(0.914)PLYSPTFSDSTSAVK;ES(0.015)S(0.985)PLYSPTFSDSTSAVK 302.64 1.1144e-137 1088181100.0 2356877.0 2337748.0 3117677.0 3708485.0 3778788.0 3692147.0 2744164.0 3820148.0 3145783.0 3212333.0 True False 3106314.859912975 3093379.3238462303 3076334.5659260377 2853551.078772099 3254168.512828807 3461276.4644244057 2988389.2798499325 3229831.904868003 3312062.6671367176 3099870.199428073 1.0020790097876004 0.9979060814923668 0.9924075422556797 0.9205388920150851 1.049775733651429 1.116587547782811 0.964036907223177 1.0419248862303678 1.0684520492979976 1.0 21.563776376255305 -6.305587125364834 24.975835140317884 1.0422440528192727 0.9806505368974563 0.3286513477328723 0.04322052054952892 547.8097734273905 309912.56408470497 0.01358042733582039 0.015398815579426272 4.947808412141067e-07 6.305587125364834 -0.06159351592181639 ESS(ph)PLYSPTFSDSTSAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ES(0.003)S(0.997)PLYSPTFSDSTSAVK;ES(0.089)S(0.89)PLY(0.021)SPTFSDSTSAVK;ES(0.169)S(0.83)PLY(0.001)SPTFSDSTSAVK;ESS(1)PLYSPTFSDSTSAVK;ES(0.019)S(0.981)PLYSPTFSDSTSAVK;ES(0.012)S(0.988)PLYSPTFSDSTSAVK;ES(0.082)S(0.918)PLYSPTFSDSTSAVK 333.65 1.1614999999999996e-198 650346000.0 294314.0 320769.0 286239.0 350990.0 350356.0 301049.0 315804.0 319823.0 284157.0 246095.0 True False 344135.5472335313 352612.8264315311 293064.02332745254 331325.16822493356 281706.2568515904 285261.46047352423 285888.75889703626 311427.98513047904 288312.2585527708 290710.0754130512 1.1837757832939617 1.2129363797609227 1.0080972354021676 1.139709959326917 0.9690281853882504 0.9812575641494868 0.9834153786752502 1.0712665692373788 0.991751861861432 1.0 18.149221547619085 -5.294082992641163 1.0306018101724246 1.0059496676690136 1.2388094228780675 0.6351226273580226 0.052707875053283684 0.5859602141617991 0.8636918398023884 0.01803504736775643 0.12512077660148452 5.080623437793028e-06 5.294082992641163 0.2328597552090539 ESS(ph)PLYSPTFSDSTSAVK ddPTM_PC-9_Lapatinib_30min_R1 9 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ES(0.096)S(0.904)PLYSPTFSDSTSAVK;ES(0.214)S(0.767)PLYS(0.011)PT(0.005)FS(0.002)DSTSAVK;ES(0.15)S(0.85)PLYSPTFSDSTSAVK;ES(0.018)S(0.942)PLY(0.038)SPTFSDSTSAVK;ES(0.123)S(0.877)PLYSPTFSDSTSAVK;ES(0.011)S(0.989)PLYSPTFSDSTSAVK;ES(0.025)S(0.975)PLYSPTFSDSTSAVK;ES(0.059)S(0.941)PLYSPTFSDSTSAVK;ES(0.057)S(0.943)PLYSPTFSDSTSAVK 331.48 9.134999999999993e-278 359285400.0 375638.0 443802.0 395894.0 374369.0 352974.0 335765.0 280250.0 295977.0 347514.0 281755.0 True False 370281.3332364276 442774.40373611386 363345.12351503357 401901.3451183735 332212.7632935847 321405.1136564441 294759.9737262184 309729.17193716083 308373.31383534777 330455.97633506166 1.1205163766231467 1.3398892301683427 1.0995265618880028 1.2162023806489453 1.0053162511327736 0.9726109880686784 0.8919795519974202 0.9372781674951911 0.9331751758747935 1.0 18.334098561741598 -6.387840553878911 2.11479567484589 0.9373776632986793 1.2040103777302191 0.7512472002054318 0.06707557790320907 0.14517763391651156 1.2785004120101142 0.02225378169750995 0.026308949431331892 4.0941094256274766e-07 6.387840553878911 0.2666327144315398 ESS(ph)PLYSPTFSDSTSAVKEK ddPTM_PC-9_Lapatinib_30min_R1 2 ESSPLYSPTFSDSTSAVKEK 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ES(0.283)S(0.709)PLY(0.007)S(0.001)PTFSDSTSAVKEK;ES(0.163)S(0.837)PLYSPTFSDSTSAVKEK 116.94 8.057100000000001e-06 28103000.0 657880.0 5223.200000000001 42820.0 11583.0 3342.6 3185.5 1934.1 1790.1 17013.0 0.0 True False 648498.5105595832 5211.10600131245 39299.50488997997 12434.852459755277 3145.9948398044467 3049.263590763187 2034.238234376018 1873.2745810813403 15096.81678516772 0.0 0.0 ESS(ph)PSHGLLK ddPTM_PC-9_AZD4547_30min_R2 2 ESSPSHGLLK 10 0 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 ES(0.345)S(0.424)PS(0.232)HGLLK;ES(0.135)S(0.836)PS(0.029)HGLLK 64.12100000000001 0.029606999999999998 11038500.0 44935.0 42965.0 89470.0 109811.0 108018.0 87854.0 57308.0 111065.0 79185.0 82749.0 True False 59223.395293937414 56852.59602363182 88283.56934134048 84495.77051303771 93021.56522640119 82360.47549177814 62408.30097969345 93902.45626979996 83370.55744061855 79851.98269683543 0.7416646812488534 0.7119747575896436 1.1055901977602267 1.0581549469326617 1.1649249284086678 1.0314142831552024 0.7815497984142943 1.1759564772024296 1.0440637116944445 1.0 16.285040609244568 -5.25655101636081 24.866359189917357 1.0463201260190818 0.7268196776448878 0.6015112737433361 0.10365452323619409 251.9602176359394 1281671.2152635653 0.027412510785561423 0.0678334847767172 5.5392247111432085e-06 5.25655101636081 -0.319500448374194 ESS(ph)PSHGLLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESSPSHGLLK 10 0 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 ES(0.183)S(0.809)PS(0.008)HGLLK 76.32600000000001 0.013199 4081600.0 23013.0 25547.0 35161.0 41305.0 44435.0 47403.0 38215.0 27600.0 35674.0 31692.0 True False 26908.646372531523 28083.137325758842 35999.371588835085 38990.814762616814 35728.28072931645 44917.103231787754 34594.99854735928 26875.529244617253 36195.66476142261 37437.50872626605 0.7187616721315778 0.7501337103143242 0.9615856613765014 1.0414906357073104 0.9543445048801975 1.1997887883034812 0.924073201566629 0.7178770745971528 0.9668288834622115 1.0 15.192196813727048 -5.247203737112783 4.745089979670694 0.969908522643696 0.7284925438226881 0.41809047147766054 0.11176007946450013 0.19393424860623326 12.428496159849606 0.03172278850350863 0.08200865795409136 5.659737160064916e-06 5.247203737112783 -0.24141597882100785 ESSAMAS(ph)PLPR ddPTM_PC-9_AZD4547_30min_R2 1 ESSAMASPLPR 11 0 Q9C0C2;E9PKK0;E9PKE7 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 ESS(0.003)AMAS(0.997)PLPR 89.9 0.0079522 8033800.0 36112.0 42538.0 53799.0 71609.0 61343.0 49514.0 60676.0 78388.0 60968.0 58062.0 True False 47594.86482373801 56287.576624071895 53085.590108357865 55100.65139802137 52826.583307255605 46417.88175267944 66076.04645501291 66274.93577704122 64190.64401136114 56029.267052697374 0.8494643483194858 1.0046102614751604 0.9474617981068557 0.9834262394722635 0.9428390926044145 0.828457772060839 1.1793130613839051 1.1828628012339952 1.145662747131561 1.0 15.77389299961434 -7.273291055364521 24.99440324126603 1.1421982314962955 0.9339598138864357 0.6600153412989859 0.07016637076296299 442.9029158775128 934049.3614484419 0.028433178173569062 0.019341197866147283 5.329775849886221e-08 7.273291055364521 -0.20823841760985984 ESSAMAS(ph)PLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESSAMASPLPR 11 0 Q9C0C2;E9PKK0;E9PKE7 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 ES(0.001)S(0.002)AMAS(0.997)PLPR 80.87100000000001 0.013813999999999998 8672600.0 58096.0 61891.0 64423.0 66933.0 74683.0 69931.0 58185.0 74810.0 60662.0 47126.0 True False 67930.50535169648 68035.12945663041 65959.08864558805 63182.961009713785 60049.40226640126 66263.69525351025 52673.295577079676 72846.3167677469 61549.066988771054 55669.57075078927 1.2202448202051814 1.2221241970985706 1.1848319962958023 1.134964041532833 1.0786755036287017 1.1903036858348826 0.9461775053534589 1.3085482030003635 1.1056141830929858 1.0 15.764601338663109 -1.5228787453989296 0.01720403491018086 7.521224458100921e-08 2.5565826047127924 0.25053773259934353 0.09007630365156824 6536.8110570508825 8.709024984752615 500.7600224733254 832.2167702093625 0.029999999991807948 1.5228787453989296 2.556582529500548 ESSANNSVS(ph)PSESLR ddPTM_PC-9_AZD4547_30min_R2 4 ESSANNSVSPSESLR 15 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 ESSANNS(0.006)VS(0.877)PS(0.116)ESLR;ESSANNS(0.073)VS(0.833)PS(0.094)ESLR;ESSANNS(0.073)VS(0.833)PS(0.094)ESLR;ESSANNS(0.002)VS(0.499)PS(0.499)ESLR 196.45 1.0422999999999998e-09 148952000.0 66692.0 61094.0 92703.0 126988.0 105718.0 90647.0 75710.0 105045.0 78664.0 90871.0 True False 87898.66872022438 80841.44074171441 91473.69764893588 97712.87854504239 91040.8805255113 84978.82876025216 82448.04333029575 88812.70894396197 82822.01844426105 87689.63394897977 1.0023838025297978 0.9219041875434236 1.043152919330896 1.1143036427988104 1.0382171349749434 0.9690863666929568 0.9402256528778109 1.0128073860547262 0.9444904114031217 1.0 16.420118687050632 -6.768885910409822 24.522055310491304 0.9720538929408116 1.0244025458338972 0.21190498284606496 0.04882498113324927 242.75647350269253 799412.0650146267 0.01883770825602878 0.016943828578431894 1.7026057258592408e-07 6.768885910409822 0.052348652893085657 ESSANNSVS(ph)PSESLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ESSANNSVSPSESLR 15 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 ESSANNS(0.003)VS(0.596)PS(0.401)ESLR;ESSANNS(0.001)VS(0.983)PS(0.01)ES(0.006)LR;ESSANNS(0.001)VS(0.774)PS(0.225)ESLR 241.39 1.2052e-32 102655000.0 79531.0 82207.0 97854.0 101628.0 103231.0 95870.0 98722.0 82466.0 89006.0 82003.0 True False 92994.02749114859 90367.96767286383 100187.2104733618 95934.11264242168 83003.62659993392 90842.40843051049 89370.3374746148 80301.35487994965 90307.54436719118 96869.49476460913 0.9599929029992584 0.9328836481748576 1.0342493342905799 0.9903438938701971 0.856860323279594 0.9377813794864489 0.9225849447422315 0.8289643202442656 0.9322598882820298 1.0 16.563754796679362 -6.240753357498655 24.715267652089864 0.9062341588215901 0.9799673167583935 0.2926545414777215 0.04981005200840924 826.2297074972867 987163.2070374136 0.014457035307887865 0.018641488368426155 5.744426043589209e-07 6.240753357498655 0.07373315793680346 ESSANNSVS(ph)PSESLR ddPTM_PC-9_Lapatinib_30min_R1 4 ESSANNSVSPSESLR 15 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 ESSANNS(0.014)VS(0.977)PS(0.009)ESLR;ESSANNS(0.005)VS(0.703)PS(0.291)ESLR;ES(0.001)S(0.011)ANNS(0.223)VS(0.765)PSESLR;ESSANNS(0.213)VS(0.73)PS(0.057)ESLR 279.19 2.9715e-75 125653000.0 138716.1 109673.8 128225.0 101209.5 111556.0 131572.0 102740.0 110233.2 137985.8 85146.5 True False 136737.98297658277 109419.85705443821 117682.83546281385 108652.78425499448 104994.4954075345 125944.97226931211 108059.37448931928 115355.03689808161 122444.38614910915 99863.95907442052 1.3692425600179043 1.0956891562139697 1.1784315037531645 1.0880079786745123 1.0513752547031567 1.261165423808759 1.0820657972191086 1.1551218073791452 1.2261118754350733 1.0 16.607676482530408 -14.522878744281957 0.01833127715805678 6.111963367249946e-07 1.9816673499176858 0.21107512738870104 0.0934450661717823 7550.879516397363 10.447629869921911 743.2415176804914 426.7317738436678 3.0000000068965662e-15 14.522878744281957 1.9816667387213491 ESSFEESNIEDPLIVT(ph)PDCQEKTSPK ddPTM_PC-9_Lapatinib_30min_R1 1 ESSFEESNIEDPLIVTPDCQEKTSPK 26 1 A0A087WUU7;Q96GX5-2;Q96GX5-3;Q96GX5 A0A087WUU7 MASTL Serine/threonine-protein kinase greatwall 1 ESSFEESNIEDPLIVT(0.722)PDCQEKT(0.171)S(0.108)PK 79.416 0.00050491 0.0 3520.3 4817.7 8862.0 1806.0 7531.4 5514.9 4235.5 4298.2 7081.0 3744.8 True False 3470.0998764560445 4806.544911648608 8133.400568309262 1938.8192646393884 7088.417859302103 5279.040582859804 4454.793465539333 4497.910063350547 6283.463213764329 4392.083690367654 0.7900805451559072 1.0943655108826627 1.8518318733649697 0.4414349546415618 1.6139077392463677 1.2019444425518004 1.0142779098925663 1.024094798834317 1.4306337621809642 1.0 12.100689829562585 -4.8160698068829815 4.756140126227109 1.1964811710130416 0.7797526222531339 0.09947481877142417 0.36514202895414094 0.3968546325921736 17.10017574814208 0.08614535990337974 0.46257187707836184 1.5273205426721394e-05 4.8160698068829815 -0.4167285487599077 ESSFEESNIEDPLIVTPDCQEKT(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 1 ESSFEESNIEDPLIVTPDCQEKTSPK 26 1 A0A087WUU7;Q96GX5-2;Q96GX5-3;Q96GX5 A0A087WUU7 MASTL Serine/threonine-protein kinase greatwall 1 ESSFEESNIEDPLIVT(0.301)PDCQEKT(0.349)S(0.349)PK 56.95 0.033309 0.0 7148.5 8600.6 7424.2 10249.0 10886.0 9293.7 8282.3 10194.0 5975.2 9856.5 True False 9421.574301963088 11380.575756100254 7325.750257113894 7886.251395471529 9374.666806037927 8712.563469824236 9019.40865505889 8618.751534816021 6291.036873387434 9511.426935085112 0.9905531910474357 1.1965161309414418 0.7702051760594574 0.8291344137209586 0.9856214919190818 0.9160101348921599 0.9482708237802577 0.9061470580217308 0.661418829826835 1.0 13.215446079769157 -5.260356735605826 24.999324510410343 0.8798431323906629 1.093534660591518 0.39268785314912047 0.10761991267176536 93.51200692083547 2159215.1729138163 0.02747614764122951 0.06477158272532313 5.490896585845044e-06 5.260356735605826 0.21369152820085502 ESSFEESNIEDPLIVTPDCQEKT(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESSFEESNIEDPLIVTPDCQEKTSPK 26 1 A0A087WUU7;Q96GX5-2;Q96GX5-3;Q96GX5 A0A087WUU7 MASTL Serine/threonine-protein kinase greatwall 1 ESSFEESNIEDPLIVT(0.002)PDCQEKT(0.499)S(0.499)PK;ESSFEESNIEDPLIVT(0.002)PDCQEKT(0.499)S(0.499)PK 93.27799999999999 6.684000000000001e-08 3026200.0 11334.400000000001 12650.900000000001 17846.5 14906.2 18610.7 16899.2 15987.0 19316.5 16540.3 15770.2 True False 13253.090055395705 13906.797745114583 18272.02824322814 14071.05394055244 14964.06693302779 16012.976202658638 14472.59562414322 18809.462342523522 16782.170596326694 18629.21242316548 0.7114144041277584 0.7465048671527004 0.9808266623502997 0.7553219975663084 0.8032581621335708 0.8595627039362358 0.7768764076223912 1.0096756596716832 0.9008523932798155 1.0 14.185279063103767 -7.759086536431302 24.99994104779466 0.9664480363357567 0.8094911453556377 0.5019270122208447 0.07535474917220203 53.56330801830505 569153.320241075 0.037526463070917504 0.020334739144224453 1.7414598398899196e-08 7.759086536431302 -0.156956890980119 ESSFEESNIEDPLIVTPDCQEKT(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 1 ESSFEESNIEDPLIVTPDCQEKTSPK 26 1 A0A087WUU7;Q96GX5-2;Q96GX5-3;Q96GX5 A0A087WUU7 MASTL Serine/threonine-protein kinase greatwall 1 ESSFEESNIEDPLIVT(0.001)PDCQEKT(0.499)S(0.499)PK 68.634 0.00024406 3644200.0 6484.0 11000.0 9542.4 8515.7 10261.0 11971.0 13714.0 14042.0 12557.0 11328.0 True False 6391.536970980024 10974.53017583798 8757.860706729212 9141.97298554244 9657.46815390218 11459.028235763964 14424.043816882648 14694.442582841284 11142.698428927937 13286.029706388796 0.48107200662862837 0.8260202948786652 0.6591781668618322 0.6880891573760654 0.7268889478139761 0.862487025017994 1.0856549424954711 1.1060070545962448 0.8386778198734417 1.0 13.69762242482099 -6.903560194961291 2.4935900477007413 1.0153320616396362 0.6791290749079744 0.6929281242686878 0.10414603205509529 0.16109011522701006 2.034747133728471 0.040335059811154074 0.03421008509902498 1.2486473650508767e-07 6.903560194961291 -0.3362029867316618 ESSFEESNIEDPLIVTPDCQEKTS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESSFEESNIEDPLIVTPDCQEKTSPK 26 1 A0A087WUU7;Q96GX5-2;Q96GX5-3;Q96GX5 A0A087WUU7 MASTL Serine/threonine-protein kinase greatwall 1 ESSFEESNIEDPLIVT(0.001)PDCQEKT(0.197)S(0.802)PK 85.399 6.0923e-07 2699600.0 18683.0 21671.0 14618.0 27576.0 33428.0 21814.0 29900.0 30133.0 26420.0 22744.0 True False 21845.6628939298 23822.353661350426 14966.548559073723 26031.00612259825 26878.02336490582 20670.03543864771 27067.655542746117 29342.040678552617 26806.3425182706 26867.307158595057 0.8130946196050468 0.8866669637090695 0.557054284254379 0.9688729119349325 1.0003988567312498 0.7693378170218003 1.0074569581152448 1.0921094736197212 0.9977308987475154 1.0 14.713564110516325 -6.719283490700901 0.7290832171637711 1.0374404406203468 0.7796188796780763 0.3713116649463759 0.11877154436690154 0.7741471820422802 0.9082147487415312 0.08703764084029436 0.09094062579286835 1.9086069867645213e-07 6.719283490700901 -0.2578215609422705 ESSIIAPAPAEDVDT(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 4 ESSIIAPAPAEDVDTPPR 18 0 Q15910-5;Q15910-3;Q15910-4;Q15910;Q15910-2 Q15910-5 EZH2 Histone-lysine N-methyltransferase EZH2 1 ESSIIAPAPAEDVDT(1)PPR;ESSIIAPAPAEDVDT(1)PPR;ESSIIAPAPAEDVDT(1)PPR;ESSIIAPAPAEDVDT(1)PPR 275.91 3.4066e-91 70791200.0 96944.0 105223.0 137364.0 152708.0 130314.0 147173.0 125689.0 156004.0 125062.0 125970.0 True False 127770.17543953443 139234.2770020856 135542.4636079568 117503.52991508116 112222.15048337563 137970.24904445425 136875.0775081433 131897.16641528736 131672.52200086683 121559.82864228367 1.051088808421457 1.1453971147969686 1.1150267742382238 0.9666312566206469 0.9231845070595962 1.1349987128598364 1.1259893917005106 1.0850390946455146 1.0831910794177078 1.0 16.891307020705298 -12.000000949973092 2.1193274808561213 0.2793018669269147 1.0702325616169468 0.08416145601667213 0.0693323240900528 1277339.9691911505 326571.8757976124 4419527.2209914345 0.018984680734759504 9.999978126085114e-13 12.000000949973092 0.7909306946900321 ESSIIAPAPAEDVDT(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ESSIIAPAPAEDVDTPPR 18 0 Q15910-5;Q15910-3;Q15910-4;Q15910;Q15910-2 Q15910-5 EZH2 Histone-lysine N-methyltransferase EZH2 1 ESSIIAPAPAEDVDT(1)PPR;ES(0.004)S(0.013)IIAPAPAEDVDT(0.983)PPR;ESSIIAPAPAEDVDT(1)PPR;ESSIIAPAPAEDVDT(1)PPR 153.68 4.7391e-05 40725200.0 55079.0 70057.5 71572.3 68052.1 74307.9 60977.3 73607.79999999999 65737.79999999999 63979.7 52136.3 True False 64402.7868401627 77012.34560611242 73278.85507145917 64239.361464885056 59747.80041872338 57779.543043598285 66635.13630967714 64012.25240495657 64915.282074799274 61588.19847927625 1.0457001248678108 1.2504399788869651 1.1898197524987957 1.0430466071596638 0.970117683160157 0.938159330363275 1.081946508503559 1.039359065300408 1.054021446927735 1.0 15.91036630796024 -5.832812288768777 5.060936032913028 1.015149345246407 1.1707585930520161 0.5392936172597251 0.06111193893766571 0.14781493319773586 6.9769806578467914 0.01769116477742829 0.02714549800190905 1.469561315778693e-06 5.832812288768777 0.15560924780560903 ESSIIAPAPAEDVDT(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 4 ESSIIAPAPAEDVDTPPR 18 0 Q15910-5;Q15910-3;Q15910-4;Q15910;Q15910-2 Q15910-5 EZH2 Histone-lysine N-methyltransferase EZH2 1 ESS(0.002)IIAPAPAEDVDT(0.998)PPR;ES(0.005)S(0.037)IIAPAPAEDVDT(0.958)PPR;ESSIIAPAPAEDVDT(1)PPR;ESSIIAPAPAEDVDT(1)PPR 161.35 9.9689e-06 63109900.0 75532.3 109064.0 129667.0 114207.0 137972.0 120206.0 111257.0 118098.0 132303.0 107040.0 True False 74455.19555107257 108811.46900887233 119006.27978909452 122606.16376338345 129856.75822338877 115065.06959387226 117017.34307531817 123585.26421794517 117401.64292764604 125541.72137816546 0.593071329066721 0.8667355187930146 0.9479420744169628 0.9766168761862096 1.0343713372562835 0.9165484456538978 0.9320992399238373 0.9844158807228163 0.9351603724948194 1.0 16.937807370266817 -4.664684460747097 1.8381913573419562 0.9663752212850826 0.3867149170661904 0.9195513839148957 0.03328414140559285 0.31370702175138027 0.8617097418477419 0.009330349714189792 0.34839559547870297 2.164290430773552e-05 4.664684460747097 -0.5796603042188921 ESSIIAPAPAEDVDT(ph)PPRK ddPTM_PC-9_Lapatinib_30min_R1 1 ESSIIAPAPAEDVDTPPRK 19 1 Q15910-5;Q15910-3;Q15910-4;Q15910;Q15910-2 Q15910-5 EZH2 Histone-lysine N-methyltransferase EZH2 1 ESSIIAPAPAEDVDT(1)PPRK 51.431000000000004 0.044368 6096800.0 39703.0 41539.0 40448.0 41873.0 41067.0 40405.0 44400.0 38333.0 47184.0 32714.0 True False 39136.827939361494 41442.81899764857 37122.52157379518 44952.48010423318 38651.519800828486 38676.97233865533 46698.8147491315 40114.09112149658 41869.64105045279 38368.57131133502 1.0200230710127982 1.0801241115122089 0.9675242080965437 1.1715964021561864 1.0073744859353122 1.008037855379546 1.2171111186341077 1.0454934794417505 1.0912483738502785 1.0 15.227637425427709 ESSKELESPLT(ph)PGK ddPTM_PC-9_AZD4547_30min_R2 1 ESSKELESPLTPGK 14 1 O15014 O15014 ZNF609 Zinc finger protein 609 1 ESSKELES(0.001)PLT(0.999)PGK 78.441 0.010053 13903000.0 107490.0 85453.0 101150.0 113380.0 125530.0 109210.0 119930.0 109910.0 109110.0 120480.0 True False 141669.58406910728 113074.01112550692 99808.68490976405 87241.99270353802 108102.32630552474 102381.08143575805 130603.53766480494 92925.93498054061 114877.33184752034 116262.03187125774 1.218536970229322 0.9725790037001842 0.8584804798550809 0.7503910889854829 0.929816248396823 0.8806063319891855 1.123355024531381 0.7992801560826129 0.9880898346480754 1.0 16.827020501821053 -4.784132137309445 3.379324109339267 0.9098845949291946 1.257719372166248 0.4442117218691185 0.10077904104424187 0.277894714884264 5.082311369177048 0.025472453325294506 0.2519367240119644 1.6438714870556435e-05 4.784132137309445 0.34783477723705347 ESSKELESPLT(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESSKELESPLTPGK 14 1 O15014 O15014 ZNF609 Zinc finger protein 609 1 ESSKELES(0.018)PLT(0.982)PGK 71.263 0.018379 7987600.0 77618.0 51579.0 68714.0 90934.0 87955.0 70277.0 85215.0 96654.0 78301.0 75488.0 True False 90757.19437462073 56699.42224626432 70352.40235929607 85839.26279200574 70720.84914025031 66591.5504044121 77142.81829682644 94116.93491337796 79446.00399406171 89173.37683732067 1.0177611030721583 0.6358335218111264 0.7889395339108917 0.9626108804716753 0.7930713364064549 0.7467649287959042 0.8650880008453463 1.0554376009005002 0.890916177134296 1.0 16.44432543007826 -7.585568886888768 6.479133985599576 0.9783554385628755 0.8177984206436425 0.30227229459083427 0.10708484152231273 0.25217627652474167 20.016657565799537 0.049865061281589844 0.02855482773095351 2.5967558167189014e-08 7.585568886888768 -0.16055701791923305 ESSKELESPLT(ph)PGK ddPTM_PC-9_Lapatinib_30min_R1 2 ESSKELESPLTPGK 14 1 O15014 O15014 ZNF609 Zinc finger protein 609 1 ESSKELES(0.007)PLT(0.993)PGK;ESSKELES(0.001)PLT(0.999)PGK 88.385 0.0041356000000000006 25517000.0 204951.0 171227.0 153596.0 199162.0 163253.0 168447.0 136440.0 128029.0 157442.0 139387.0 True False 202028.36115658973 170830.53440165546 140967.9297777057 213809.03786495567 153650.7795077471 161242.9144791355 143504.19559395275 133977.6947328433 139709.2240222402 163479.857228497 1.235799716133916 1.044963809595725 0.8622954054864005 1.3078616625295505 0.939875909562291 0.986316707224457 0.8778096459515246 0.8195364065285528 0.8545959507841236 1.0 17.318753362962894 -6.773508403059238 1.83809595859836 0.8777219221869357 1.08864147920973 0.3574323217477037 0.12503554501878375 0.3875343127187368 2.703408358601512 0.051588282812371926 0.04678475413961319 1.6845798319296385e-07 6.773508403059238 0.2109195570227944 ESSLDGLGGTGKDNLTSAT(ph)LPR ddPTM_PC-9_Lapatinib_30min_R1 4 ESSLDGLGGTGKDNLTSATLPR 22 1 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 ESS(0.001)LDGLGGT(0.002)GKDNLT(0.042)S(0.138)AT(0.817)LPR;ESSLDGLGGT(0.004)GKDNLT(0.016)S(0.016)AT(0.964)LPR;ESSLDGLGGT(0.091)GKDNLT(0.044)S(0.07)AT(0.794)LPR;ESSLDGLGGTGKDNLT(0.012)S(0.112)AT(0.875)LPR 64.707 0.0022583000000000004 44821400.0 250156.0 116867.0 125910.0 92181.0 60784.0 102106.0 63968.0 50770.0 78744.0 44274.2 True False 246588.72956700771 116596.40164178687 115558.16582665556 98960.29824680138 57208.804625941964 97739.16440071144 67279.95004217207 53128.959544997306 69875.02150891947 51926.93647833675 4.748763287236892 2.245393422938197 2.2253992564122274 1.9057603809939057 1.1017173071592379 1.8822439956858799 1.2956656911628208 1.0231483532089751 1.3456411305540898 1.0 15.664195493134535 -1.9858622536028434 0.7012551155154078 1.3065835365234666 199.99999998860102 0.9028534244012849 0.3302156404229312 38.90732995728777 0.42231369727828905 0.12759684804685276 11829.298514238651 0.01033089021541585 1.9858622536028434 198.69341645207754 up ESSLS(ph)PSPASSISSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESSLSPSPASSISSR 15 0 H3BRS1;Q12968;I3L3K7;H3BR83;Q12968-5;Q12968-6;Q12968-4;Q12968-3;Q12968-2 H3BRS1 NFATC3 Nuclear factor of activated T-cells, cytoplasmic 3 1 ESS(0.003)LS(0.327)PS(0.176)PAS(0.131)S(0.09)IS(0.176)S(0.097)R;ESS(0.006)LS(0.63)PS(0.328)PAS(0.016)S(0.005)IS(0.01)S(0.006)R 98.654 0.011519 0.0 20843.0 16854.1 15386.3 17315.4 19323.5 20011.2 20046.5 15378.2 16321.800000000001 11601.599999999999 True False 24371.30823198516 18527.2636631335 15753.167744867698 16345.27427528422 15537.198889905414 18961.77744429574 18147.55039590836 14974.538544549747 16560.47544718809 13704.878241784929 1.7782944001413492 1.3518736420908546 1.1494569646622412 1.1926610355025968 1.1336984259031142 1.3835786870753075 1.3241672108095153 1.092642946574581 1.2083635589476969 1.0 13.742401890438174 -4.783835769643209 2.658206181315909 1.199896348218454 1.8933180961583027 0.746034340984955 0.10418713090361009 0.23894772176459275 2.2422865843637663 0.02724092788067393 0.3737502279017773 1.6449936671582132e-05 4.783835769643209 0.6934217479398488 ESSLSPS(ph)PASSISSR ddPTM_PC-9_AZD4547_30min_R2 1 ESSLSPSPASSISSR 15 0 H3BRS1;Q12968;I3L3K7;H3BR83;Q12968-5;Q12968-6;Q12968-4;Q12968-3;Q12968-2 H3BRS1 NFATC3 Nuclear factor of activated T-cells, cytoplasmic 3 1 ES(0.011)S(0.007)LS(0.095)PS(0.855)PAS(0.032)S(0.001)ISSR 178.22 3.9383e-05 4973300.0 13787.0 9207.7 16752.0 21062.0 16184.0 19367.0 12498.0 22808.0 14606.0 14588.0 True False 18170.979212585178 12183.90895861269 16529.85753443765 16206.481304656189 13937.130956174708 18155.978428406972 13610.297788165853 19283.547675699807 15378.043341260014 14077.278560241632 1.290801992361319 0.8655017307836492 1.1742225220379472 1.1512510202382478 0.9900444106815687 1.289736389793748 0.9668273402364382 1.3698349146945354 1.0924017220695004 1.0 13.781080836597878 -6.741343557082039 24.997804126564937 1.155816572394808 1.0892467470177598 0.02143194811442317 0.1547089080960003 909.976102805061 1131943.987038417 0.0478972064104589 0.047843117283377506 1.8140800317753548e-07 6.741343557082039 -0.06656982537704814 ESSLSPSPASSIS(ph)SR ddPTM_PC-9_AZD4547_30min_R2 1 ESSLSPSPASSISSR 15 0 H3BRS1;Q12968;I3L3K7;H3BR83;Q12968-5;Q12968-6;Q12968-4;Q12968-3;Q12968-2 H3BRS1 NFATC3 Nuclear factor of activated T-cells, cytoplasmic 3 1 ESS(0.021)LS(0.195)PS(0.195)PAS(0.105)S(0.105)IS(0.319)S(0.058)R 88.10799999999999 0.0049521999999999995 4126600.0 5268.0 6656.5 9546.7 12734.0 8051.0 8412.2 7771.8 11440.0 7998.3 6302.4 True False 6943.114418792973 8808.083450047834 9420.10452029703 9798.373038338812 6933.257620375834 7886.18380417438 8463.475144028434 9672.210865047615 8421.073809146925 6081.754894301262 1.1416300951718432 1.448279913138427 1.5489122274762959 1.6111094920185132 1.1400093790153316 1.2966954343332562 1.3916172701992475 1.590365122098342 1.3846453787602746 1.0 12.570271958988446 -6.25200975831136 24.92090227853002 1.3344337748179733 1.4462133548046285 0.09677056029776299 0.18784995179255923 1972.3865039518164 5212682.533381953 0.05753909382135421 0.07325104905011381 5.59745024251276e-07 6.25200975831136 0.11177957998665522 ESSPIPS(ph)PTSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESSPIPSPTSDR 12 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 ESSPIPS(0.918)PT(0.079)S(0.003)DR 102.97 0.0022415 6311300.0 38520.0 41353.0 57055.0 54098.0 65907.0 58537.0 64435.0 58718.0 49967.0 49144.0 True False 45040.67519532067 45458.252547543954 58415.40758229246 51067.06444808241 52992.99646735814 55467.216671500915 58331.25033099819 57176.71471686362 50697.672846723224 58053.41817631007 0.7758488063274881 0.7830417910877495 1.0062354537829798 0.8796564621395784 0.9128316321773979 0.9554513483262126 1.0047858018255589 0.9848983317953153 0.8732935017323663 1.0 15.82509339480272 -5.248259373982626 24.37714566209049 0.9496100403730696 0.7794452438441564 0.6825961554119957 0.04708033063557781 317.96274256584525 588085.8083939304 0.012130729103415167 0.03165397092634503 5.645996778587085e-06 5.248259373982626 -0.17016479652891325 ESSPIPS(ph)PTSDR ddPTM_PC-9_Lapatinib_30min_R1 2 ESSPIPSPTSDR 12 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 ESSPIPS(0.842)PT(0.148)S(0.01)DR;ES(0.007)SPIPS(0.468)PT(0.468)S(0.058)DR 126.32 0.00026707 13492000.0 76479.0 68983.0 79859.0 64813.0 79216.0 87052.0 71132.0 78030.0 85572.0 75379.0 True False 75388.39543546924 68823.27410180282 73293.3012846545 69579.56422982982 74556.67062464822 83328.98888812341 74814.86690845086 81655.55866252005 75933.98024689188 88408.15971379618 0.8527311922284568 0.7784719682504926 0.82903321957981 0.7870264968197485 0.8433234089026466 0.9425486194700176 0.8462439117684284 0.9236201604791194 0.8589023964836846 1.0 16.43189191019963 -6.5751714338030975 5.55988166370875 0.9048394749263027 0.8110307127496335 0.5380978512714403 0.04484084455139195 0.1538371719010907 10.36051765188928 0.01381202150530531 0.013913659079985137 2.6596749700126464e-07 6.5751714338030975 -0.09380876217666922 ESSPIPS(ph)PTSDRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESSPIPSPTSDRK 13 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 ESSPIPS(0.967)PT(0.017)S(0.017)DRK 94.48700000000001 0.0017215999999999998 4875400.0 31765.0 24826.0 24232.0 30612.0 30542.0 30333.0 34661.0 35618.0 30365.0 32779.0 True False 37142.187112652144 27290.561210681815 24809.782780371756 28896.908885443067 24557.51434758148 28742.284081805312 31377.659156091086 34683.06524039049 30809.030680063843 38721.573221578794 0.9592117267578765 0.7047895769760023 0.6407224892026272 0.7462741433589111 0.6342075567811911 0.7422808964225602 0.8103405038978353 0.895703928193245 0.7956554477723172 1.0 15.24084994871314 -7.490850840381753 2.3463241093101344 0.8866524445562416 0.7271694851586208 0.3506712339689537 0.09611499159745067 0.35738655521589874 3.896293168571777 0.05260474763380811 0.028856604873602143 3.2296031472171125e-08 7.490850840381753 -0.1594829593976208 ESSPIPS(ph)PTSDRK ddPTM_PC-9_Lapatinib_30min_R1 2 ESSPIPSPTSDRK 13 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 ESSPIPS(0.351)PT(0.324)S(0.324)DRK;ESSPIPS(0.925)PT(0.038)S(0.038)DRK 183.06 8.880200000000001e-05 28303600.0 126611.0 93287.0 110041.0 102362.0 126028.0 137179.0 111013.0 122944.0 146203.0 111561.0 True False 124805.50392238602 93070.99968303635 100993.85375054403 109890.04294962215 118615.28082058135 131312.17394986752 116760.70994921916 128656.42706913831 129736.07855415708 130844.17020431138 0.9538484116449663 0.7113117805532128 0.7718636114459171 0.8398543303689446 0.9065385231559435 1.0035768024270806 0.8923646331884632 0.9832797813478664 0.9915312111466332 1.0 16.997490120605754 -6.343377262083183 2.3322540322798853 0.9679455128087681 0.80339622150582 0.5568955512573226 0.06467148131637755 0.2217457342886497 2.365138514814951 0.021621047110487547 0.026089219065629665 4.5354745875528353e-07 6.343377262083183 -0.16454929130294804 ESSPIPSPT(ph)SDR ddPTM_PC-9_AZD4547_30min_R2 1 ESSPIPSPTSDR 12 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 ESSPIPS(0.282)PT(0.713)S(0.006)DR 134.18 0.00013844 7717400.0 54632.0 45043.0 69789.0 81727.0 79819.0 73879.0 56105.0 77892.0 63927.0 60894.0 True False 72003.8395838075 59602.26888612701 68863.5522606774 62886.10281956303 68737.50962623022 69259.3344509877 61098.23631021327 65855.58118009505 67306.05071044288 58762.11959469109 1.225344492003531 1.014297464033476 1.1719038172152478 1.0701809814437757 1.1697588531581895 1.178639145910676 1.0397554875766128 1.1207148692785551 1.1453986203132758 1.0 15.842598815498066 -11.581216505226216 2.365651471262582 0.8313379993715019 1.1227421130078001 0.26140278907388803 0.06340843455084509 17468206.056398448 5572795.852393814 15922386.167006345 0.015238365616227037 2.6229106395144434e-12 11.581216505226216 0.29140411363629826 ESSPIPSPTS(ph)DR ddPTM_PC-9_AZD4547_30min_R2 1 ESSPIPSPTSDR 12 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 ESSPIPS(0.041)PT(0.041)S(0.917)DR 102.9 0.0022624000000000003 9095200.0 28358.0 27489.0 34235.0 46227.0 40561.0 39575.0 26525.0 41923.0 31074.0 30719.0 True False 37375.254116957316 36374.281673306505 33781.021531248356 35570.07935003047 34929.80528382367 37100.36899386616 28885.673614266223 35444.76364470199 32716.50820117169 29643.537160135886 1.260823022402971 1.2270560519418043 1.1395745841247478 1.1999269573627165 1.1783278458009614 1.2515500020610932 0.9744341054248808 1.1956995365710774 1.1036641148603643 1.0 14.855429984376704 -6.417288445490054 0.024637089994881914 1.0658302882761277e-06 2.344666681955469 0.4813138447774392 0.06809517049646913 444.3670918847557 3.4333204044771026 149.13150304851652 177.22837569779654 3.825705669152926e-07 6.417288445490054 2.3446656161251807 ESSPIPSPTS(ph)DRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESSPIPSPTSDRK 13 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 ESSPIPS(0.194)PT(0.194)S(0.612)DRK 71.316 0.012001999999999999 14173000.0 32216.0 29697.0 31931.0 43399.0 46209.0 44493.0 37499.0 40240.0 39136.0 36565.0 True False 37669.532504996096 32645.12189936432 32692.356138991847 40967.4947314564 37154.67816408204 42159.708754549974 33946.823250750385 39183.74263780431 39708.289961962095 43193.94505161928 0.8721021536694278 0.7557800488089591 0.756873587256792 0.9484545734939899 0.8601825584507281 0.9760559889624961 0.7859162484506093 0.9071582276399494 0.9193022289237155 1.0 15.398541468414061 -1.5228986469556953 0.042953576361343726 1.3169171633587298 0.12145173258464384 0.3541439644593931 0.06745867508506839 748.7905394025724 2.452501708025787 17.9071117492256 63.18495021593787 0.02999862527246876 1.5228986469556953 -1.195465430774086 ESSPIPSPTS(ph)DRK ddPTM_PC-9_Lapatinib_30min_R1 1 ESSPIPSPTSDRK 13 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 ESSPIPS(0.254)PT(0.342)S(0.404)DRK 81.904 0.019793 0.0 3618.7 5184.7 5372.6 3897.6 5491.0 6276.1 5002.9 4622.9 6709.5 5156.8 True False 3567.096674411695 5172.6951456970155 4930.88556683574 4184.2425060124515 5168.030175721358 6007.685833303668 5261.925682622297 4837.696810726177 5953.805455832762 6048.14600899592 0.58978349218191 0.8552530210089551 0.8152722436762632 0.6918223369258734 0.8544817152288502 0.9933103176358388 0.8700063911809982 0.7998644218460766 0.9844017401327882 1.0 12.562277252910176 -6.477393756278432 5.860003196691564 0.9146283903862386 0.753332008206133 0.5035799612699985 0.08850492196423351 0.20123057953722429 17.309432226767427 0.027830528481112615 0.030949892131948233 3.331242462611939e-07 6.477393756278432 -0.16129638218010556 ESSPLY(ph)SPTFS(ph)DSTSAVK ddPTM_PC-9_AZD4547_30min_R2 1 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 ES(0.159)S(0.177)PLY(0.608)S(0.356)PT(0.081)FS(0.593)DS(0.021)T(0.004)S(0.001)AVK 77.631 0.010898999999999999 0.0 16151.0 17866.0 24018.0 23858.0 24440.0 17590.0 15193.0 23613.0 16791.0 19044.0 True False 21286.68203833056 23640.83511132795 23699.50562691759 18357.906702425586 21046.927865108115 16490.094519320417 16545.14756725907 19964.153422759555 17678.5379804941 18377.27535654247 1.158315453479469 1.2864167648721445 1.2896093227704923 0.9989460540944669 1.1452692228184538 0.8973089970842605 0.9003047103698567 1.0863500184564707 0.961978184334077 1.0 14.165635265818104 -5.767020909660632 24.980251415248414 0.9999876548757329 1.2489441559780239 0.6731699420797594 0.07858881841182934 76.69904962458335 343270.0234193115 0.022679244242752344 0.0347308666288499 1.7099329862082453e-06 5.767020909660632 0.24895650110229095 ESSPLY(ph)SPTFSDSTSAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ESSPLY(0.956)S(0.042)PT(0.001)FSDSTSAVK 122.55 8.2073e-05 34727000.0 33409.0 43904.0 35172.0 44446.0 48841.0 42688.0 43975.0 48840.0 42474.0 35686.0 True False 39064.48384217206 48262.49896857228 36010.63387055282 41955.83471587617 39270.95665805212 40449.366132070856 39809.36964857059 47558.001750257485 43095.101897086526 42155.589309779454 0.9266738878943793 1.1448659539288215 0.8542315375057252 0.995261492077945 0.931571763105251 0.9595255764266405 0.9443438058956377 1.128154119748594 1.0222867857546263 1.0 15.363436306918604 -7.740131226446575 24.997708692475996 1.0564153899815498 0.9674953117136144 0.20511900248737025 0.07623011837197466 337.3297995894981 395740.03738516103 0.03455307893840175 0.019923769712730476 1.8191511007515434e-08 7.740131226446575 -0.08892007826793547 ESSPLYS(ph)PTFSDSTSAVK ddPTM_PC-9_Lapatinib_30min_R1 1 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ESSPLYS(0.78)PT(0.161)FS(0.057)DS(0.001)T(0.001)SAVK 124.04 4.5153e-05 4406000.0 18811.0 15131.0 16230.0 16112.0 26003.0 25212.0 24912.0 23656.0 29170.0 25798.0 True False 18542.751690485096 15095.965099145866 14895.632049611748 17296.93022805638 24473.55466386498 24133.74153204253 26201.821464647852 24755.144120473822 25884.567426282392 30257.149926325765 0.6128386756728745 0.49892224270638774 0.4923012275076028 0.5716642271388186 0.8088519481661864 0.7976211107393346 0.8659712341858906 0.8181584908278217 0.8554859756887105 1.0 14.884988478776112 -6.278508152112359 2.6566500665192665 0.854222984600308 0.5282649253605083 0.8714187327432918 0.05939319254321333 0.09309968787197807 1.3054532374857897 0.0187978948964943 0.023417236355600966 5.266133297779105e-07 6.278508152112359 -0.3259580592397997 ESSPLYS(ph)PTFSDSTSAVKEK ddPTM_PC-9_AZD4547_30min_R2 1 ESSPLYSPTFSDSTSAVKEK 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ESSPLY(0.246)S(0.75)PT(0.003)FSDSTSAVKEK 86.557 0.0011792 0.0 6442.7 1494.8 6754.7 31488.0 17501.0 5946.6 5244.3 8864.6 5614.7 6369.2 True False 8491.344583515092 1977.9648675928022 6665.128264557423 24228.928084750463 15071.288239249474 5574.758161943769 5711.03254044473 7494.779758243103 5911.4815793627695 6146.216246633603 1.3815564312703705 0.32181830059691935 1.0844278816593929 3.942088451251792 2.452124629930536 0.9070227825122762 0.9291948592880651 1.2194136127813813 0.9618082641658757 1.0 12.585482811836629 -6.787685768699845 24.924412005609522 1.0125575712524728 1.827465834916276 0.1791437053679258 0.8912549123416036 465.2086401280871 441773.54225130245 0.35744055698631233 0.3153299052405013 1.6304753270938002e-07 6.787685768699845 0.8149082636638032 ESSPLYS(ph)PTFSDSTSAVKEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESSPLYSPTFSDSTSAVKEK 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ES(0.011)S(0.011)PLY(0.422)S(0.542)PT(0.01)FS(0.003)DSTSAVKEK 61.648 0.033754 0.0 3290.0 3396.9 2842.2 6167.7 4103.4 13770.0 5572.9 9771.0 9556.2 4954.8 True False 3846.9320195380287 3734.1217826699854 2909.9688271035257 5822.143764953193 3299.3682265033676 13047.87695930041 5044.994567697984 9514.521603230267 9695.941346445787 5853.066017824781 0.6572507482100284 0.6379770484901732 0.4971699991494337 0.9947169137034473 0.5636991307556679 2.2292379617049822 0.8619404859494295 1.6255619831136332 1.656557660022629 1.0 12.514976835848769 -6.723060652494763 24.99996018043906 1.4754634579050312 0.676794132227174 0.5407471438479493 0.37067471744847263 122.26704491893676 79644.58372997897 0.11526793388201274 0.11526580741521453 1.8920793570622154e-07 6.723060652494763 -0.7986693256778572 ESSPLYSPT(ph)FSDSTSAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ESSPLY(0.159)S(0.069)PT(0.369)FS(0.101)DS(0.148)T(0.148)S(0.005)AVK 90.434 0.0032755 9412400.0 7682.5 7128.7 8216.1 8877.4 10792.0 11180.0 11143.0 11481.0 10632.0 9318.0 True False 8982.99551370849 7836.390224062982 8412.002983732766 8380.028058919119 8677.38507102022 10593.701118734823 10087.45437166622 11179.635915125033 10787.472886232132 11007.279638752587 0.816095875504304 0.7119279677854219 0.7642217931955861 0.761316904261805 0.7883314820557784 0.9624268181066551 0.916434823382882 1.0156583899045903 0.9800307832875803 1.0 13.426170341947255 -6.7428042722364845 3.300586083658733 0.9759535262459403 0.7602831115976931 0.9043728888379408 0.03365682279901023 0.06881561014079705 1.5593312897210927 0.0120845319460972 0.011387126547049676 1.8079887664970522e-07 6.7428042722364845 -0.2156704146482472 ESSSIYISK ddPTM_PC-9_Lapatinib_30min_R1 2 ESSSIYISK 9 0 O60701;O60701-2;O60701-3 O60701 UGDH UDP-glucose 6-dehydrogenase 0 ; 123.86 0.0068065 10170300.0 39769.0 38232.0 35040.0 41018.0 32562.0 34655.0 35741.0 30046.0 38799.0 34549.0 False True 39201.88676725858 38143.4761529671 32159.146458311498 44034.6005520368 30646.767179355138 33172.88643475065 37591.4940979439 31442.046848315684 34429.04804841719 40520.748616351215 0.9674521845196009 0.9413319707912597 0.7936464047787709 1.0867173498928806 0.7563228278311803 0.8186642045740611 0.9277097630613546 0.7759493079954591 0.8496646588242979 1.0 15.306373207566109 -5.025845016690901 21.50552319137401 0.8708788000760312 0.9609223234656794 0.0918578133169684 0.09889736457493568 240.2637560059749 199929.41813811424 0.024299199803178184 0.06514541476391064 9.42225781352556e-06 5.025845016690901 0.09004352338964816 ESSTESSQSAKPVSGQDTSGNT(ph)EGSPAAEK ddPTM_PC-9_AZD4547_30min_R2 1 ESSTESSQSAKPVSGQDTSGNTEGSPAAEK 30 1 Q96S66-4;Q96S66-3;Q96S66-2;Q96S66 Q96S66-4 CLCC1 Chloride channel CLIC-like protein 1 1 ESS(0.002)T(0.001)ES(0.012)S(0.011)QS(0.013)AKPVS(0.065)GQDT(0.174)S(0.174)GNT(0.439)EGS(0.108)PAAEK 62.364 0.00040254 15315000.0 17654.0 15528.0 22000.0 25558.0 20480.0 18952.0 22446.0 25118.0 25021.0 18206.0 True False 23267.60477398844 20547.122333409858 21708.265625455348 19665.997967163763 17636.705510532487 17766.928444011402 24443.650516336285 21236.590254219052 26343.558978616114 17568.613481475117 1.324384806946918 1.169535794903529 1.2356277089450005 1.1193824707851985 1.0038757770571463 1.0112880258163455 1.3913249638117668 1.2087800939221278 1.4994671609341037 1.0 14.100712717604285 -7.268841426672297 24.961083727000215 1.2922913883395333 1.1418502496824698 0.15075209835434422 0.14986850216504224 988.4793329925179 3333322.4373052227 0.06115743465119268 0.04212279041717958 5.384663560830429e-08 7.268841426672297 -0.15044113865706343 ESSTESSQSAKPVSGQDTSGNTEGS(ph)PAAEK ddPTM_PC-9_AZD4547_30min_R2 1 ESSTESSQSAKPVSGQDTSGNTEGSPAAEK 30 1 Q96S66-4;Q96S66-3;Q96S66-2;Q96S66 Q96S66-4 CLCC1 Chloride channel CLIC-like protein 1 1 ESSTESSQSAKPVS(0.001)GQDT(0.06)S(0.06)GNT(0.267)EGS(0.611)PAAEK 76.329 9.994299999999999e-07 14573000.0 24916.0 35923.0 46592.0 45331.0 37504.0 30166.0 42015.0 45026.0 29753.0 32298.0 True False 32838.76971500488 47534.40723744731 45974.15963732801 34880.63830696847 32297.21696616264 28279.715251268906 45754.25360616007 38068.2662945484 31325.682838046625 31167.256850746086 1.0536304132334566 1.5251392660278162 1.4750787936676395 1.1191436729258863 1.0362547182393276 0.9073533608265542 1.4680231187899617 1.2214185700348894 1.0050830905029342 1.0 14.927743563002352 -5.777327735159716 24.610835652087196 1.1210365712783237 1.3686684414476114 0.26048378487633495 0.1861393575688238 265.01712740519275 410506.9720339993 0.053927415416413854 0.08029741289132238 1.6698300213814857e-06 5.777327735159716 0.24763187016928767 ESSTESSQSAKPVSGQDTSGNTEGS(ph)PAAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESSTESSQSAKPVSGQDTSGNTEGSPAAEK 30 1 Q96S66-4;Q96S66-3;Q96S66-2;Q96S66 Q96S66-4 CLCC1 Chloride channel CLIC-like protein 1 1 ESSTESSQSAKPVSGQDTSGNT(0.04)EGS(0.959)PAAEK;ESSTESSQSAKPVSGQDT(0.009)S(0.038)GNT(0.295)EGS(0.659)PAAEK 121.93 1.1152e-17 26981000.0 86517.0 86172.0 72488.0 62635.0 116386.0 66732.0 79581.0 63948.0 60068.0 61441.0 True False 101162.61931135898 94726.58666909183 74216.38883227097 59125.76401540985 93580.99878389182 63232.45644502787 72042.51156345413 62269.432758506715 60946.380862508646 72579.7669333117 1.3938129534682855 1.305137652978815 1.0225492856771372 0.8146314946111117 1.2893538066866024 0.8712132749493066 0.9925977253364398 0.8579447880525932 0.8397158524703981 1.0 16.147279803620826 -5.250150670341119 3.1416119693996247 0.9559056416887806 1.3756101360008282 0.5993913926662346 0.12883502111707906 0.16876424495350545 3.395882960931064 0.03446097470788868 0.10161600682241757 5.6214626523196405e-06 5.250150670341119 0.4197044943120476 EST(ph)PLASGPSSFQR ddPTM_PC-9_Lapatinib_30min_R1 2 ESTPLASGPSSFQR 14 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6 A0A087WVP4 SMTN Smoothelin 1 ES(0.15)T(0.804)PLAS(0.045)GPS(0.001)S(0.001)FQR;EST(1)PLASGPSSFQR 173.06 0.00028536 13511700.0 59717.0 56116.0 68793.0 59620.0 61636.0 48449.0 48070.0 47400.0 54584.0 43535.0 True False 58865.42462924344 55986.06684975673 63137.1050886593 64004.65368648967 58010.69166103839 46376.949210135215 50558.82939168357 49602.377042207416 48436.175124998204 51059.96674325886 1.1528684482939873 1.0964767590090183 1.236528519615515 1.2535192983638168 1.13612866128036 0.9082839682079911 0.9901853177050599 0.9714533754324491 0.9486135266900255 1.0 15.63990497762838 -6.651167675022465 5.213627427437707 0.9642655084538795 1.1833658323387648 0.8367818216549527 0.04697863825535867 0.08596486652766376 3.602081480755885 0.016814638698928297 0.0167266197048874 2.23271003829864e-07 6.651167675022465 0.21910032388488532 ESTESSNT(ph)TIEDEDVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESTESSNTTIEDEDVK 16 0 H0Y9J2;D6R938;E9PBG7;E9PF82;Q13557-8;Q13557-12;Q13557-10;Q13557;Q13557-6;Q13557-11 H0Y9J2 CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 1 ESTESSNT(0.712)T(0.288)IEDEDVK 220.1 4.8782e-22 3380400.0 17981.0 25394.0 22234.0 21753.0 22472.0 16512.0 22261.0 15022.0 15207.0 15082.0 True False 21024.82815906181 27914.948496900593 22764.14288291457 20534.24993417755 18068.77291660176 15646.081652285278 20152.276924316753 14627.688417124651 15429.373606182475 17816.247210953683 1.1800929741329278 1.5668253906882301 1.2777181756278533 1.1525575330787283 1.0141738999609762 0.8781917688404012 1.1311179445201482 0.8210308402170879 0.8660282619280382 1.0 14.120905861172531 -5.992547990063344 1.6450353054623428 0.9397957918609522 1.3809173558157979 0.6841540011964227 0.12021144137926182 0.2020648950550762 1.1040495399954753 0.039651115936560045 0.06734630494067374 1.0173069463265716e-06 5.992547990063344 0.4411215639548457 ESTESSNT(ph)TIEDEDVKAR ddPTM_PC-9_Lapatinib_30min_R1 1 ESTESSNTTIEDEDVKAR 18 1 H0Y9J2;D6R938;E9PBG7;E9PF82;Q13557-8;Q13557-12;Q13557-10;Q13557;Q13557-6;Q13557-11 H0Y9J2 CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 1 ES(0.003)T(0.003)ES(0.018)S(0.018)NT(0.776)T(0.182)IEDEDVKAR 68.88 0.008325299999999999 2271300.0 13094.0 9639.0 11435.0 9710.7 9577.8 10101.0 8409.2 7495.3 11539.0 9581.8 True False 12907.277158854493 9616.681487718399 10494.858440376487 10424.85727194558 9014.452634679303 9669.003776581054 8844.587229468398 7843.559000937922 10239.356308943172 11238.001363054042 1.148538493800895 0.8557288059542437 0.9338723231409541 0.9276433535787114 0.8021401976614045 0.8603846417360999 0.7870249294101163 0.6979496395795377 0.9111367740714104 1.0 13.45609785994829 -1.522889558947823 0.9459432403492546 0.8402477356173279 198.35592678955538 0.4770903469337001 0.08553966457102168 993.5206741333598 1.760725957328076 0.027684859493022854 424540.52988241875 0.029999253027613033 1.522889558947823 197.51567905393804 ESTHQSEDVFLPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 ESTHQSEDVFLPSPR 15 0 A0A0A0MSK6;Q13017-2;Q13017 A0A0A0MSK6 ARHGAP5 Rho GTPase-activating protein 5 1 ESTHQSEDVFLPS(1)PR;ESTHQSEDVFLPS(1)PR 147.06 6.4037e-05 4102000.0 3613.7 7263.6 22681.0 61705.0 34053.0 23729.9 10621.4 35219.0 15843.3 22309.6 True False 4762.781430370573 9611.416652560274 22380.235120497855 47479.8655827467 29325.328747566564 22246.065601706745 11566.684023621769 29776.71280210766 16680.744493261995 21528.54769451375 0.22123096726976624 0.44644983902047464 1.0395608397774618 2.205437461759034 1.3621601031192512 1.0333286721136254 0.5372719139140713 1.383126870638647 0.7748197755816502 1.0 14.393963378822686 -5.254880789259892 3.8775935755172997 1.203484926242954 0.2957577061052821 0.388781140643256 0.4218431556492514 0.22569379536556394 7.858250042072323 0.11939878489410514 0.3196901529906847 5.5605686997173995e-06 5.254880789259892 -0.9077272201376718 ESTLHLVLR ddPTM_PC-9_AZD4547_30min_R2 1 ESTLHLVLR 9 0 P62987;P0CG48;M0R2S1;Q96C32;Q5PY61;J3QKN0;F5GXK7;F5H747;F5H388;B4DV12;F5H265;F5H2Z3;F5GYU3;F5H6Q2;J3QTR3;J3QS39;P0CG47;M0R1M6;P62979;A0A2R8Y422 P62987;P62979 UBA52;UBC;UBB;RPS27A Ubiquitin-60S ribosomal protein L40;Ubiquitin;60S ribosomal protein L40;Polyubiquitin-C;Ubiquitin;Polyubiquitin-B;Ubiquitin;Ubiquitin-40S ribosomal protein S27a;Ubiquitin;40S ribosomal protein S27a 0 110.76 0.0019140000000000001 4471100.0 33833.0 32371.0 86319.0 115880.0 92623.0 87244.0 65263.0 109440.0 73438.0 82769.0 False True 44591.19022988283 42834.29270059314 85174.35366016722 89165.65632815303 79763.89523935808 81788.61888820864 71071.28056881654 92528.56268101471 77319.78275335164 79871.28250292291 0.558288146033601 0.5362915350586189 1.0663952172929019 1.1163669035224266 0.9986554959404728 1.0240053286388078 0.8898227040014747 1.1584709770702455 0.9680548543905264 1.0 16.285389258949834 -5.25964370973283 24.99649158768836 1.0304512876047072 0.5472897890715569 0.8787380963017168 0.07138203914709337 45.077617081665906 627487.2258309444 0.018152568100293986 0.043233465319581 5.499918959390286e-06 5.25964370973283 -0.48316149853315027 ESTLHLVLR ddPTM_PC-9_Lapatinib_30min_R1 2 ESTLHLVLR 9 0 P62987;P0CG48;M0R2S1;Q96C32;Q5PY61;J3QKN0;F5GXK7;F5H747;F5H388;B4DV12;F5H265;F5H2Z3;F5GYU3;F5H6Q2;J3QTR3;J3QS39;P0CG47;M0R1M6;P62979;A0A2R8Y422 P62987;P62979 UBA52;UBC;UBB;RPS27A Ubiquitin-60S ribosomal protein L40;Ubiquitin;60S ribosomal protein L40;Polyubiquitin-C;Ubiquitin;Polyubiquitin-B;Ubiquitin;Ubiquitin-40S ribosomal protein S27a;Ubiquitin;40S ribosomal protein S27a 0 ; 101.46 0.0029303000000000003 8779500.0 85492.0 94466.0 134854.0 113777.0 130593.0 147601.0 119504.0 107654.0 147803.0 106924.0 False True 84272.86840268748 94247.26978097367 123766.82467149374 122144.54012894549 122911.77649571655 141288.44930473616 125691.33238243718 112655.99785024884 131155.86970541032 125405.6709327259 0.6720020536224061 0.7515391375843983 0.9869316415354827 0.9739953482204975 0.9801133838808038 1.1266511973013613 1.0022778989784642 0.8983325635304272 1.045852781057797 1.0 16.936243063737315 -5.188632058564486 2.657819262380954 1.0040097010704363 0.6759610483192293 0.8218051009456925 0.054620576219857275 0.11908211443366751 1.5840462668597786 0.0154591453541217 0.05641715619602797 6.4769111794476855e-06 5.188632058564486 -0.328048652751207 ESTPGDS(ph)PSTVNK ddPTM_PC-9_AZD4547_30min_R2 2 ESTPGDSPSTVNK 13 0 Q5T6F2 Q5T6F2 UBAP2 Ubiquitin-associated protein 2 1 ESTPGDS(0.993)PS(0.006)T(0.002)VNK;ES(0.013)T(0.126)PGDS(0.747)PS(0.096)T(0.017)VNK 173.33 6.273600000000001e-19 3579200.0 44124.0 50519.0 52274.0 52999.0 50957.0 50549.0 45251.0 60432.0 44464.0 49101.0 True False 58154.514163785316 66848.27879711063 51580.81260477519 40780.89937638752 43882.500131845896 47388.16303906358 49278.251337197406 51093.622989209536 46814.27626494493 47381.98893518125 1.2273548550978077 1.4108373307958715 1.0886164503423008 0.860683569703584 0.9261430581117507 1.0001303048694468 1.0400207430002621 1.0783342813891965 0.9880183866698176 1.0 15.53205113884303 -5.4338859064425575 4.8242454588254455 0.9873731305015621 1.3141242522276562 0.7804583035356413 0.06990998755762275 0.09818870973338661 3.826317527282907 0.019613402383688965 0.04188650102517862 3.682256975556756e-06 5.4338859064425575 0.3267511217260941 ESTPGDS(ph)PSTVNK ddPTM_PC-9_Lapatinib_30min_R1 1 ESTPGDSPSTVNK 13 0 Q5T6F2 Q5T6F2 UBAP2 Ubiquitin-associated protein 2 1 ESTPGDS(0.976)PS(0.019)T(0.005)VNK 155.09 3.5476999999999997e-09 0.0 14257.0 22081.0 22246.0 23402.0 21986.0 17829.0 18393.0 14529.0 18808.0 16787.0 True False 14053.692565586412 22029.872801152596 20417.019752043318 25123.061146783486 20692.826706139105 17066.49523142893 19345.299542359826 15204.070380722189 16689.64498297975 19688.610582728536 0.7137980867941363 1.1189145475038187 1.0369964739895747 1.276020013764822 1.0510049258778829 0.8668207012230813 0.9825629625348031 0.7722266798277617 0.8476801810291493 1.0 14.265073683976617 -6.756114345675204 23.07181637179786 0.8851663075648792 1.0567852665269735 0.19761211895418562 0.1439302464618821 73.5947599331586 318863.227187693 0.04862092872189867 0.04715850149602742 1.7534187822952527e-07 6.756114345675204 0.17161895896209423 ESTPSEEPS(ph)PPHNSK ddPTM_PC-9_AZD4547_30min_R2 1 ESTPSEEPSPPHNSK 15 0 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 ESTPS(0.022)EEPS(0.963)PPHNS(0.014)K 64.298 0.020533000000000003 8971000.0 15332.0 18518.0 48890.0 98466.0 53884.0 51930.0 29143.0 70577.0 31330.0 47931.0 True False 20207.25707458881 24503.58136077303 48241.6866558415 75766.18498453496 46403.13670554359 48682.808890750995 31736.670542528227 59670.94634811758 32986.03983853731 46252.95027906098 0.43688579761228274 0.5297733704106216 1.0429969626754996 1.6380832904152025 1.0032470669563018 1.0525341323532833 0.6861545123294682 1.2901003284785277 0.713166179444132 1.0 15.497257771496676 -5.247725921901355 5.036858501644721 1.0711658325474342 0.47031128518053233 0.4416640768876834 0.25646688364654696 0.15841971021701762 12.486272105845202 0.06770188909400597 0.17303189778536657 5.652936123623865e-06 5.247725921901355 -0.6008545473669019 ESTPSEEPS(ph)PPHNSK ddPTM_PC-9_Lapatinib_30min_R1 2 ESTPSEEPSPPHNSK 15 0 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 ESTPS(0.002)EEPS(0.988)PPHNS(0.01)K;ESTPSEEPS(0.992)PPHNS(0.008)K 74.133 0.009243000000000001 11333100.0 34759.0 29142.0 80260.0 31789.0 48918.0 70424.0 39581.0 44723.0 85443.0 42186.0 True False 34263.33028598008 29074.523489479157 73661.33261255952 34126.86910499533 46040.73941648833 67412.12968636226 41630.31050867961 46800.993849338454 75819.50958532207 49477.79389068838 0.6924991514714316 0.5876277255553005 1.488775606594344 0.689741122661856 0.9305333927823549 1.3624724221798636 0.8413938301423409 0.9458989613145687 1.532394709287779 1.0 15.59449355460265 -5.220785390499338 24.99520183092168 1.0765597470009194 0.6400631087094646 0.31791615032072473 0.2672342850135508 616.7559800627946 379196.88923435897 0.06588178793155278 0.17433492733232833 6.014708848883035e-06 5.220785390499338 -0.4364966382914548 ESTQLS(ph)PADLTEGKPTDPSK ddPTM_PC-9_AZD4547_30min_R2 2 ESTQLSPADLTEGKPTDPSK 20 1 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 ES(0.233)T(0.195)QLS(0.569)PADLTEGKPT(0.002)DPSK;ES(0.103)T(0.089)QLS(0.807)PADLT(0.001)EGKPTDPSK 80.585 0.00066317 170567000.0 159423.0 185387.0 202944.0 166830.0 181624.0 223550.0 234550.0 254300.0 218520.0 209624.0 True False 210116.19779560252 245309.72230962483 200252.82995874615 128369.92099780626 156408.64265844531 209571.38316055038 255424.4956164432 215003.77823265764 230070.5210825783 202285.1275645795 1.0387130300942313 1.2126928225670457 0.9899533019045874 0.6345989077067674 0.7732088094737062 1.0360197295950229 1.2626953780123995 1.0628748678719235 1.1373575697458447 1.0 17.626030728205635 -6.996885043305352 24.78090364926762 1.1250266842032743 0.9296986917009543 0.23844073929951537 0.15677137108334108 136.65308862999993 1087123.6480657735 0.06261389223560959 0.05492918987672989 1.0071982364974995e-07 6.996885043305352 -0.19532799250232002 ESTQLS(ph)PADLTEGKPTDPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ESTQLSPADLTEGKPTDPSK 20 1 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 ES(0.12)T(0.101)QLS(0.774)PADLT(0.003)EGKPT(0.002)DPSK;ES(0.16)T(0.137)QLS(0.336)PADLT(0.004)EGKPT(0.228)DPS(0.135)K;ES(0.022)T(0.018)QLS(0.96)PADLTEGKPTDPSK;ES(0.273)T(0.233)QLS(0.478)PADLT(0.016)EGKPTDPSK;ES(0.024)T(0.021)QLS(0.9)PADLT(0.055)EGKPTDPSK 131.26 1.8458e-05 117694600.0 304311.0 509639.0 360451.0 351294.0 376567.0 257838.0 370019.0 247264.0 241961.0 275356.0 True False 355824.8418837799 560232.5918331869 369045.5188580292 331612.13609051507 302781.3995588273 244316.5213821422 334968.121614427 240773.58199786415 245499.22187976041 325275.86308310286 1.0939171400887875 1.7223306596532073 1.1345616467205988 1.0194796900924474 0.9308449655284488 0.751105597158075 1.0297970419306763 0.7402134905298838 0.7547415893476216 1.0 18.31130424639391 -5.705551649055093 2.0809408702031194 0.8634981784124813 1.4106610465918983 0.5779389563179272 0.1768698917446631 0.2004953379731262 1.7640230952781863 0.050430430534309616 0.10364799435839486 1.9699189180299204e-06 5.705551649055093 0.547162868179417 ESTQLS(ph)PADLTEGKPTDPSK ddPTM_PC-9_Lapatinib_30min_R1 6 ESTQLSPADLTEGKPTDPSK 20 1 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 ES(0.012)T(0.054)QLS(0.928)PADLT(0.004)EGKPT(0.001)DPSK;ES(0.071)T(0.185)QLS(0.314)PADLT(0.063)EGKPT(0.287)DPS(0.08)K;ES(0.072)T(0.057)QLS(0.872)PADLTEGKPTDPSK;ES(0.028)T(0.023)QLS(0.95)PADLTEGKPTDPSK;ES(0.105)T(0.091)QLS(0.797)PADLT(0.007)EGKPTDPSK;ES(0.035)T(0.035)QLS(0.928)PADLT(0.002)EGKPTDPSK 109.23 4.1411999999999996e-05 222584200.0 393276.0 568133.0 491479.0 560687.0 700343.0 599104.0 656194.0 640836.0 574666.0 508761.0 True False 387667.81212201447 566817.522944487 451071.49378380383 601921.7923770015 659150.2016673144 573481.718499636 690168.5145380998 670611.5800468347 509941.0635787456 596699.6609685797 0.6496866639621366 0.9499209736845047 0.7559439418008247 1.0087516915963135 1.104659923213905 0.961089398925993 1.1566430478907912 1.1238678751019886 0.8546025696595753 1.0 19.186645431622757 -5.826925079995255 5.6730732145297775 1.0428182897946896 0.8019159048709187 0.5195615908187925 0.1072566378927075 0.1543179439057363 9.317283022432175 0.029302917690897667 0.04456825558624966 1.4896180290855734e-06 5.826925079995255 -0.24090238492377092 ESTQLS(ph)PADLTEGKPTDPSKLESPSFTGTGDTEIAHATEDLENNGSK ddPTM_PC-9_AZD4547_30min_R2 1 ESTQLSPADLTEGKPTDPSKLESPSFTGTGDTEIAHATEDLENNGSK 47 2 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 ES(0.082)T(0.076)QLS(0.179)PADLT(0.179)EGKPT(0.076)DPS(0.076)KLES(0.076)PS(0.076)FT(0.076)GT(0.076)GDT(0.028)EIAHATEDLENNGSK 47.766999999999996 0.00016659 5185800.0 9786.7 8692.7 11265.0 12887.0 15444.0 14187.0 10863.0 13939.0 12733.0 14122.0 True False 12898.667023994161 11502.445279986598 11115.618739579753 9916.10125216525 13299.867182844908 13299.884647276796 11829.785955580553 11785.04783635477 13406.040385065304 13627.593078402266 0.9465110199420802 0.8440555286477026 0.8156699921717194 0.7276487634401716 0.9759513001546285 0.9759525817038932 0.8680759608480699 0.864793053957 0.9837423459841863 1.0 13.734243153688958 -6.287397086675888 24.989450026667182 0.9357183679610556 0.8329557883332582 0.40085734587809974 0.06609703638573716 872.1690873802286 839633.282017522 0.02146677482703115 0.024348863035729636 5.159444122249922e-07 6.287397086675888 -0.10276257962779733 ESTQLSPADLT(ph)EGKPTDPSKLESPSFTGTGDTEIAHATEDLENNGSK ddPTM_PC-9_Lapatinib_30min_R1 1 ESTQLSPADLTEGKPTDPSKLESPSFTGTGDTEIAHATEDLENNGSK 47 2 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 ES(0.007)T(0.007)QLS(0.087)PADLT(0.245)EGKPT(0.074)DPS(0.074)KLES(0.074)PS(0.074)FT(0.163)GT(0.163)GDT(0.03)EIAHATEDLENNGSK 48.515 0.00010677 11712000.0 11604.0 13725.0 18204.0 13423.0 16720.0 19227.0 12988.0 16146.0 17030.0 17379.0 True False 11438.524832087021 13693.220605761493 16707.3373894721 14410.172197815342 15736.562472784768 18404.706030326113 13660.455089227933 16896.202103870903 15111.902066149773 20382.936993938118 0.5611813859547737 0.6717982109169967 0.819672719119961 0.7069723171935882 0.7720458772680708 0.9029467164520829 0.6701907135998384 0.8289385434933068 0.7413996359133156 1.0 14.315074325130956 -14.522875646724751 0.03608783192678319 2.20412584877215 3.218047064711933e-10 0.5316208149176715 0.08225681905677786 877.8361166146848 2.3653741449334955 123.16925279669286 41.47533363511774 3.000021404140066e-15 14.522875646724751 -2.204125848450345 ESTQLSPADLTEGKPT(ph)DPSKLESPSFTGTGDTEIAHATEDLENNGSK ddPTM_PC-9_Lapatinib_30min_R1 1 ESTQLSPADLTEGKPTDPSKLESPSFTGTGDTEIAHATEDLENNGSK 47 2 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 ES(0.011)T(0.011)QLS(0.027)PADLT(0.128)EGKPT(0.149)DPS(0.149)KLES(0.149)PS(0.149)FT(0.149)GT(0.051)GDT(0.027)EIAHAT(0.002)EDLENNGSK 44.317 0.00018552 7155100.0 7310.2 7648.8 10175.0 8597.7 12126.0 12817.0 9767.6 10694.0 11696.0 8420.6 True False 7205.9552074735075 7631.089673540872 9338.450776635827 9230.003539086421 11412.77252063326 12268.846787886285 10273.318534766142 11190.882280366372 10378.673315659878 9876.089490255785 0.7296364836085418 0.7726833258315515 0.9455615793932997 0.9345807921438114 1.1555963047817295 1.2422778064122755 1.0402212884869342 1.1331288858214401 1.0508889501153231 1.0 13.269724193901316 -5.580380926234602 1.2731281793881357 1.1102446153542236 0.722758421643724 0.7693053972612947 0.07391887090058714 0.2439454881775359 0.7319696038556581 0.025224006502745283 0.08474990285676083 2.627961955680728e-06 5.580380926234602 -0.38748619371049964 ESTQLSPADLTEGKPTDPS(ph)KLESPSFTGTGDTEIAHATEDLENNGSK ddPTM_PC-9_AZD4547_30min_R2 1 ESTQLSPADLTEGKPTDPSKLESPSFTGTGDTEIAHATEDLENNGSK 47 2 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 ES(0.005)T(0.005)QLS(0.004)PADLT(0.031)EGKPT(0.164)DPS(0.409)KLES(0.164)PS(0.069)FT(0.069)GT(0.055)GDT(0.021)EIAHAT(0.002)EDLENNGSK 43.841 0.00090223 5754900.0 8187.7 8781.3 14911.0 14603.0 15335.0 17953.0 14720.0 15218.0 15577.0 15710.0 True False 10791.218285260295 11619.683497319158 14713.270397325672 11236.503964100964 13205.999951367952 16830.396071936302 16030.051483581492 12866.407774850928 16400.368418924227 15159.997681751849 0.7118218954775783 0.7664700048935903 0.9705324965211635 0.7411943062251514 0.8711083094203944 1.1101846072308519 1.0573914205064114 0.8487077666468429 1.0818186627208668 1.0 13.887981912443324 -6.578952284105042 6.3788409683148215 1.0116772059903067 0.8073108976566812 0.5656322863084613 0.0923570162067169 0.16467558862626006 13.925918236361499 0.03111366037395268 0.03121171484347575 2.636621055226014e-07 6.578952284105042 -0.20436630833362557 ESTQLSPADLTEGKPTDPS(ph)KLESPSFTGTGDTEIAHATEDLENNGSK ddPTM_PC-9_Lapatinib_30min_R1 1 ESTQLSPADLTEGKPTDPSKLESPSFTGTGDTEIAHATEDLENNGSK 47 2 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 ESTQLS(0.002)PADLT(0.007)EGKPT(0.051)DPS(0.179)KLES(0.179)PS(0.179)FT(0.179)GT(0.051)GDT(0.174)EIAHATEDLENNGSK 66.683 2.2899e-10 9209900.0 23320.0 26051.0 27892.0 24671.0 33545.0 41742.0 31877.0 32589.0 34248.0 31515.0 True False 22987.452523635755 25990.680510068665 25598.82742623358 26485.387640043384 31571.94905200748 39956.79196535458 33527.435084641096 34103.20391199363 30390.62959257177 36962.32575890209 0.6219157493924583 0.703166805021976 0.6925653865292365 0.7165508959799313 0.8541656512078011 1.0810140093993221 0.9070704939763233 0.9226476746739927 0.8222055557543596 1.0 15.173767917019557 -6.328588149758927 3.0213664130809654 0.9411378502360571 0.6809263693005625 0.7744455249934371 0.06685759243416092 0.12754852408573059 2.293929963887875 0.022178424443449224 0.026408468042898724 4.692581782288317e-07 6.328588149758927 -0.2602114809354946 ESTSS(ph)KSPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESTSSKSPPR 10 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347 A0A494C1K3 GTF2I General transcription factor II-I 1 EST(0.003)S(0.042)S(0.736)KS(0.219)PPR;ESTS(0.001)S(0.5)KS(0.5)PPR 155.47 0.0013493000000000001 301620000.0 159117.0 165954.0 170342.0 207727.0 212629.0 197294.0 200425.0 181586.0 204608.0 166059.0 True False 186052.36539599762 182428.81636822288 174403.599305632 196088.72965002028 170965.87382004783 186947.55532376296 181439.29304865896 176819.5599062703 207600.00491969363 196164.1821776796 0.9484522777327259 0.929980256043809 0.8890695404712695 0.9996153603230635 0.8715448045718769 0.9530157506248083 0.9249358931607439 0.9013855533836063 1.0582972009215006 1.0 17.581702116850373 -8.260370598676644 24.999996811997658 1.0291486064041815 0.9274053294612491 0.5555237407656645 0.03645850985569885 63.840409238875424 1493397.063812946 0.02603802162279856 0.008566418023662802 5.490721314280494e-09 8.260370598676644 -0.10174327694293239 ESTSSKS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 3 ESTSSKSPPR 10 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347 A0A494C1K3 GTF2I General transcription factor II-I 1 EST(0.005)S(0.083)S(0.182)KS(0.729)PPR;EST(0.001)SS(0.012)KS(0.987)PPR;ESTSS(0.011)KS(0.989)PPR 129.74 0.0011401 363910000.0 213075.0 186715.0 218252.0 305494.0 288904.0 273337.0 222753.0 232553.0 222135.0 248957.0 True False 280828.4177646763 247066.97233916927 215357.83587667634 235067.0781352502 248794.6664460387 256245.19418007327 242577.5854702594 196617.277386313 233876.60260240955 240241.09120661282 1.1689441483728422 1.0284126295725406 0.8964238165712612 0.9784632468768099 1.0356041308190262 1.0666168426603446 1.0097256229228377 0.8184165181684829 0.9735079100238948 1.0 17.874123407369893 -7.556811211086099 24.94889737756747 0.9203914048888933 1.0224433942440514 0.23716121441704585 0.07809965277635479 260.7020221850551 191678.8224687812 0.03769663636727554 0.021764295767006638 2.7745259360124205e-08 7.556811211086099 0.10205198935515813 ESTSSKS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESTSSKSPPR 10 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347 A0A494C1K3 GTF2I General transcription factor II-I 1 ES(0.001)T(0.007)S(0.007)S(0.007)KS(0.978)PPR 95.477 0.028482999999999998 76586000.0 15555.0 17873.0 18334.0 18233.0 22215.0 22269.0 19474.0 19634.0 16031.0 17134.0 True False 18188.15427474591 19647.31332145799 18771.152092082182 17211.464122183555 17862.13022171184 21101.174437665988 17629.28174044942 19118.628303942573 16265.42304732764 20240.258567330628 0.898612743223697 0.9707046605210026 0.9274166152393083 0.8503579173619953 0.8825050412420484 1.0425348257025207 0.8710008166054 0.9445841929510498 0.8036173546508598 1.0 14.304940099987942 -10.600104615602364 4.645962051561689 1.0000044589774089 0.9136207815333783 0.15133121448419562 0.06335557886258415 88099577.6488099 11.257212757597783 4202.453151851464 0.015018595938899256 2.5112814252863042e-11 10.600104615602364 -0.08638367744403053 ESTSSKS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 3 ESTSSKSPPR 10 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347 A0A494C1K3 GTF2I General transcription factor II-I 1 ES(0.011)T(0.182)S(0.121)S(0.082)KS(0.604)PPR;EST(0.005)S(0.08)S(0.005)KS(0.91)PPR;ESTSS(0.001)KS(0.999)PPR 117.86 0.0044481 292987000.0 195177.0 178853.0 205183.0 168636.0 201908.0 188831.0 164022.0 169588.0 208266.0 168829.0 True False 192393.74018892183 178438.8768671955 188313.6457692841 181038.05399320487 190032.16840640106 180755.13831656045 172514.25659419037 177467.6775914318 184808.88994179366 198010.86769949782 0.9716322261710374 0.901156986686181 0.9510268196747147 0.9142834234126433 0.9597057505691795 0.9128546347813357 0.8712363043426424 0.8962522090492404 0.9333270041635314 1.0 17.595220088306867 -6.833009495789285 24.947723368414117 0.9130309886680892 0.9366602461813498 0.014011669683566153 0.03704811557296107 113.97837369808668 39727.40597168085 0.012435441128671386 0.010967031037161405 1.468894160123388e-07 6.833009495789285 0.023629257513260615 ESVAS(ph)GDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESVASGDDR 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ES(0.002)VAS(0.998)GDDR;ES(0.001)VAS(0.999)GDDR 107.45 0.0025013 8437500.0 47236.0 114266.0 82630.0 58046.0 54917.0 48465.0 60120.0 27262.0 42795.0 39620.0 True False 55232.1218464737 125609.57332231429 84600.21257602022 54793.87080767111 44156.40807498305 45923.410082243616 54424.99836889288 26546.40138647666 43420.795914814145 46802.792368252594 1.1801031317084174 2.6838051100454883 1.8075889983309303 1.170739351971637 0.94345670077872 0.9812109012836276 1.1628579325068347 0.5671969564893673 0.927739430014596 1.0 15.514306986615647 -5.7957353430681025 3.1040888103494377 0.9320169499207341 1.9991208884591227 0.578275324930394 0.3664203425364663 0.15597699322253078 3.0756837086813666 0.10172058115504991 0.17231454278739436 1.6005330885174928e-06 5.7957353430681025 1.0671039385383887 ESVAS(ph)GDDRAEEDMDEAIEK ddPTM_PC-9_AZD4547_30min_R2 2 ESVASGDDRAEEDMDEAIEK 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ES(0.042)VAS(0.958)GDDRAEEDMDEAIEK;ES(0.039)VAS(0.961)GDDRAEEDMDEAIEK 65.753 0.017504 14910000.0 54539.0 55010.0 55537.0 45401.0 53825.0 70202.0 67635.0 71230.0 66906.0 54287.0 True False 71881.26751832759 72790.90672081892 54800.54309276884 34934.50088845768 46352.32783712947 65812.25784225893 73654.38397364353 60223.040202564844 70442.51456869379 52386.42865367683 1.3721352908695081 1.3894993148327544 1.0460828214698803 0.6668616621951332 0.884815572055152 1.2562844907283022 1.405982157336354 1.1495923992203272 1.3446710604073535 1.0 15.676905491885643 -6.823961695457553 24.975605914667764 1.2515736861812694 1.0655896520575963 0.10975290438943952 0.22296913603376803 151.58335437218219 60550.72406080492 0.0877385033710527 0.07737811369601022 1.4998171127409876e-07 6.823961695457553 -0.18598403412367315 ESVAS(ph)GDDRAEEDMDEAIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESVASGDDRAEEDMDEAIEK 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ES(0.045)VAS(0.955)GDDRAEEDMDEAIEK 61.141000000000005 0.03517 0.0 14753.0 17974.0 10992.0 9969.0 13274.0 13000.0 11737.0 9705.5 10200.0 8519.6 True False 17250.391514967945 19758.339933972264 11254.090967392136 9410.469249934074 10673.054988206293 12318.25711480794 10625.186391478628 9450.74090882727 10349.155703495842 10064.136038883504 1.71404593979253 1.9632425334509107 1.118237166500051 0.9350498854125241 1.0605038472224728 1.2239756167062408 1.0557474929221413 0.9390513872540736 1.0283203310757272 1.0 13.296935708200447 -5.301192075113889 6.386576154871398 1.043800199601747 1.8389648589270364 0.915293377165318 0.09661308213592772 0.04623852000179103 5.523651404325097 0.025812095398776963 0.05588111785824956 4.9981343395293175e-06 5.301192075113889 0.7951646593252895 ESVAS(ph)GDDRAEEDMDEAIEK ddPTM_PC-9_Lapatinib_30min_R1 1 ESVASGDDRAEEDMDEAIEK 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 ES(0.025)VAS(0.975)GDDRAEEDMDEAIEK 76.068 0.0010466 22099000.0 22735.0 22415.0 16838.0 17072.0 18425.0 17467.0 17141.0 21201.0 18631.0 16949.0 True False 22410.794730911624 22363.0994446735 15453.644636559617 18327.531830522512 17341.277724943735 16719.977127565708 18028.477108442854 22186.07585805569 16532.580586872376 19878.612066877093 1.1273822667053202 1.1249829399274913 0.7774005843350293 0.9219724077749331 0.872358576474199 0.8411038492685067 0.9069283633983158 1.1160777112313303 0.831676805767538 1.0 14.278929410386528 -5.235582473487341 24.020979590601513 0.9093212850223529 1.1261827653226961 0.48485644668976646 0.08977254999716681 393.8080890825404 365843.83856684767 0.022918646728332513 0.06058068103651796 5.813230272908163e-06 5.235582473487341 0.21686148030034325 ESVDSRDS(ph)SHSR ddPTM_PC-9_AZD4547_30min_R2 1 ESVDSRDSSHSR 12 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 ESVDS(0.005)RDS(0.735)S(0.259)HS(0.001)R 67.846 0.016947999999999998 6538900.0 22305.0 17602.0 27881.0 45354.0 36881.0 34056.0 20979.0 31399.0 29917.0 32334.0 True False 29397.526027178676 23291.502274129336 27511.27972287824 34898.33601231495 31760.70976239986 31926.472936326136 22846.090358291854 26547.006027240386 31498.351543233985 31201.996501703634 0.9421681085559241 0.7464747415396197 0.8817153646362379 1.1184648395947834 1.0179063304704146 1.0232189127571676 0.7321996320666356 0.850811134018008 1.0094979512453368 1.0 14.929350724372668 -5.531831841258666 24.98054626686863 0.9569466392702516 0.8367647953675846 0.17152359343984036 0.10947583041695279 340.78093535562897 950829.5213095366 0.03208551767152693 0.05567438589454963 2.9387873295917777e-06 5.531831841258666 -0.12018184390266695 ESVDSRDS(ph)SHSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESVDSRDSSHSR 12 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 ESVDS(0.024)RDS(0.462)S(0.462)HS(0.052)R 52.00899999999999 0.046399 4644000.0 22839.0 20649.0 27286.0 27509.0 37459.0 28481.0 28036.0 25017.0 27731.0 21653.0 True False 26705.191609188183 22698.896255513137 27936.601722731262 25967.759915381306 30119.17785168147 26987.40622206498 25380.22711693745 24360.330257702546 28136.513413102286 25578.51749494631 1.0440476706464508 0.8874203229330192 1.092190027363816 1.0152175520145723 1.1775185116820115 1.0550809376421848 0.9922477767506254 0.9523745956940449 1.1000056363181085 1.0 14.642645029043852 -5.276916292023595 24.811646601456786 1.048083730527868 0.9657339804202667 0.18013275287172348 0.07027073840120719 1088.2303179584671 1744583.9807297129 0.018622791766840948 0.03899702944120464 5.285471166337595e-06 5.276916292023595 -0.08234975010760137 ESVEAIGR ddPTM_PC-9_Lapatinib_30min_R1 1 ESVEAIGR 8 0 F5GXX6;Q9NQ89 F5GXX6 C12orf4 Protein C12orf4 0 102.77 0.019242 2983800.0 18593.0 17125.0 18560.0 21899.0 22079.0 16128.0 15966.0 17000.0 22596.0 13040.0 False True 18327.86041046139 17085.34811465687 17034.068443671847 23509.525512922475 20780.35662898414 15438.24303620426 16792.64135776201 17789.88206155118 20051.000533571372 15293.946625292201 1.1983735042040677 1.117131407167471 1.113778468109856 1.5371784725627229 1.358730819330757 1.0094348708314065 1.0979926744344302 1.1631976034316316 1.3110416182839453 1.0 13.900673123856434 -6.75617911257172 24.999932216099143 1.125386912635733 1.2635370073709564 0.21708014328710334 0.14066435081873077 251.90609947829287 1197208.321842165 0.05138299545031152 0.04993773366161489 1.7531573121867435e-07 6.75617911257172 0.13815009473522344 ESVFTVEGGHR ddPTM_PC-9_Lapatinib_30min_R1 1 ESVFTVEGGHR 11 0 F5H3X6;F5GWA7;F5GY37;J3KPX7;Q99623-2;Q99623;F5H2D2;F5H0C5 F5H3X6 PHB2 Prohibitin-2 0 82.48899999999999 0.015638 0.0 38165.0 51642.0 50001.0 55709.0 59541.0 64047.0 59490.0 50937.0 53853.0 48419.0 False True 37620.760101396176 51522.42612187499 45890.11078944158 59806.02569977617 56038.915442109945 61307.85911084915 62570.10111319444 53303.71897466076 47787.50804276945 56788.15963573792 0.6624754234458531 0.9072740946767872 0.808092938454058 1.053142522726499 0.9868063307838478 1.0795887647020506 1.1018159685847229 0.9386414230813649 0.8415047846117524 1.0 15.793302537879995 -4.210193830403598 0.8300604286712217 1.0009907229223602 0.09781963247602526 0.5639478281918382 0.08594917716721709 4.289523406268821 1.1702887972531686 0.03228628363626598 4.44550941950464 6.163198701326307e-05 4.210193830403598 -0.903171090446335 ESVNS(ph)PVFGK ddPTM_PC-9_AZD4547_30min_R2 2 ESVNSPVFGK 10 0 E7ESJ3;Q9UPS8-2;Q9UPS8 E7ESJ3 ANKRD26 Ankyrin repeat domain-containing protein 26 1 ES(0.011)VNS(0.989)PVFGK;ES(0.02)VNS(0.98)PVFGK 147.52 0.00014744 39233000.0 180573.0 157299.0 213456.0 309020.0 279940.0 228412.0 217793.0 264120.0 187801.0 229960.0 True False 237991.45784827296 208142.82560040156 210625.43397032705 237780.2133114072 241075.16311613622 214129.36153195106 237176.15507905316 223306.322873809 197727.77745665974 221909.1703943767 1.0724723878031486 0.9379640563321037 0.9491515541967184 1.071520446355707 1.0863686376173536 0.964941472005869 1.0687983496019744 1.0062960556201859 0.8910302224340624 1.0 17.759609762562633 -8.067037624292771 10.070703592486028 0.9462864782763475 1.0192309200282854 0.21400129214785468 0.05738875147284669 0.9755406100730694 142.19139212580745 0.03918666391848071 0.014806383587514066 8.5696360057052e-09 8.067037624292771 0.07294444175193793 ESVNS(ph)PVFGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESVNSPVFGK 10 0 E7ESJ3;Q9UPS8-2;Q9UPS8 E7ESJ3 ANKRD26 Ankyrin repeat domain-containing protein 26 1 ES(0.267)VNS(0.733)PVFGK;ES(0.022)VNS(0.978)PVFGK 139.48 0.00012118 23365000.0 142168.0 139432.0 159225.0 180622.0 204954.0 185631.0 184980.0 194890.0 164806.0 132049.0 True False 166234.23445400666 153273.88748601396 163021.52786417483 170502.334924425 164794.73497459968 175896.18357530073 167457.35526077476 189774.3440030241 167215.9759676803 155988.43840069105 1.0656830477845864 0.9825977428679415 1.045087248360149 1.0930446940333602 1.056454803087955 1.1276232096347565 1.0735241469026264 1.2165923702341734 1.0719767290582705 1.0 17.251079577369758 -5.923457037605466 1.2411692870352484 1.1070212190406263 1.0210415669706832 0.16594163501134873 0.05674979696864886 0.656032980946308 2.0452540786531745 0.020062382179966243 0.04189251634507955 1.192732250544004e-06 5.923457037605466 -0.08597965206994318 ESVNS(ph)PVFGK ddPTM_PC-9_Lapatinib_30min_R1 2 ESVNSPVFGK 10 0 E7ESJ3;Q9UPS8-2;Q9UPS8 E7ESJ3 ANKRD26 Ankyrin repeat domain-containing protein 26 1 ESVNS(1)PVFGK;ESVNS(1)PVFGK 175.48 0.00038469 37476000.0 260750.0 215837.0 230410.0 222390.0 204750.0 223700.0 186196.0 166728.0 229480.0 160050.0 True False 257031.65718430604 215337.24268748588 211466.5792083209 238745.30247129267 192707.00755398834 214132.8724701698 195836.31781597514 174474.79155048818 203633.54586847036 187714.42924677997 1.369269577281125 1.147153383741169 1.1265334266356 1.271853759081166 1.0265966677534675 1.1407374133645243 1.043267257619912 0.9294692595054256 1.084804970430708 1.0 17.518180026058296 -1.5228787461800561 0.24124526487663606 0.9797415225228271 2.992088426420246 0.6136947362603504 0.07677748469717813 34.37558873470664 0.4603480748917708 0.10394394212050782 27.741903200735408 0.02999999993784964 1.5228787461800561 2.012346903897419 ESVPEFPLS(ph)PPK ddPTM_PC-9_AZD4547_30min_R2 6 ESVPEFPLSPPK 12 0 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK 219.84 3.5841000000000004e-11 1226960100.0 1152642.0 1331768.0 994480.0 865936.0 969818.0 1216782.0 1249373.0 1169035.0 1307586.0 1104588.0 True False 1519158.1795570187 1762235.9618573259 981292.5454183102 666307.833777836 835175.5109772265 1140696.4291874808 1360564.7766437943 988387.5025018299 1376702.326470272 1065916.710330423 1.4252128377705005 1.6532585940143965 0.9206090268667614 0.6251030941913721 0.7835279275416659 1.0701553115101057 1.2764269135268866 0.9272652290022174 1.2915665108988756 1.0 20.023663281072494 -5.265024164273467 24.77821596901561 0.9773728622227034 1.539235741186436 0.5551397581612557 0.1976554565541638 192.86809680361299 1333126.2726074148 0.05600783454532387 0.12450500836131179 5.432201057241514e-06 5.265024164273467 0.5618628789637325 ESVPEFPLS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 12 ESVPEFPLSPPK 12 0 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK;ES(0.001)VPEFPLS(0.999)PPK;ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK 192.39 5.5197e-05 1119925000.0 1861203.3 3082279.0 1744127.8 1997946.7 2118060.2 1380566.4 2308338.6 1762226.5 1465165.9 1429663.3 True False 2176268.258249194 3388267.2890477423 1785714.4213935125 1886008.223829595 1703041.5084323646 1308167.0676357527 2089676.056883775 1715969.9216083146 1486591.179465943 1688849.939081547 1.2886096081649037 2.0062571639078812 1.057355292539871 1.1167411504039662 1.0084030967005484 0.7745904697413066 1.2373367275130498 1.0160582547325172 0.8802387619319221 1.0 20.687609714064607 -5.355102493466407 7.590931474875942 1.0127509117572373 1.6450005909741598 0.6217842042470942 0.19857597105316907 0.1499570819404611 10.63057092598712 0.048965681531974316 0.10258244314926025 4.414662490554632e-06 5.355102493466407 0.6322496792169225 ESVPEFPLS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 6 ESVPEFPLSPPK 12 0 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK 198.48 8.5593e-06 1243267300.0 498031.10000000003 1347756.2 1046309.6 1206320.1 1634760.4 1438415.7 1738529.1 1676465.1 1282978.2 1596677.4 True False 490929.0851862821 1344635.5533247953 960286.063559855 1295036.9043198836 1538607.0073346056 1376898.0136217684 1828541.6301097802 1754359.7887827419 1138475.6847566126 1872660.9611510981 0.26215588158815195 0.7180347010054969 0.5127922691193288 0.6915490476844472 0.8216153587079883 0.7352628383812779 0.9764402996823309 0.9368272341750329 0.6079454361331951 1.0 20.83665829755386 -4.698072651326123 0.4688167256796932 0.8841673810572152 1.0453534724106308e-17 0.5962572352604675 0.13735212517394577 3.840783672181511 0.6173475452608148 0.09204836165680602 1.9241162897461146 2.0041367355827517e-05 4.698072651326123 -0.8841673810572152 ESVPEFPLS(ph)PPKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESVPEFPLSPPKK 13 1 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 ESVPEFPLS(1)PPKK 91.355 0.0023633000000000005 7038600.0 49410.0 68137.0 40042.0 49810.0 56839.0 39232.0 56241.0 47149.0 35626.0 39070.0 True False 57774.13710801642 74901.19105825466 40996.753140130626 47019.30718619882 45701.8059721755 37174.60485601115 50913.44533042085 45911.388708494895 36146.96285222971 46153.08172205015 1.251793703743388 1.6228860189517915 0.8882776969699939 1.0187685292471993 0.9902221968060033 0.8054631125152055 1.1031429198387934 0.9947632313046654 0.7831971669826784 1.0 15.494139361909832 -5.2703418844467835 24.97947242685083 0.9522808642767406 1.4373398664615844 0.710847675939561 0.1248188092449724 275.4938021064721 773007.4025539357 0.030901788922186826 0.06586315260549913 5.366092016160251e-06 5.2703418844467835 0.48505900218484377 ESVPEFPLS(ph)PPKKK ddPTM_PC-9_AZD4547_30min_R2 2 ESVPEFPLSPPKKK 14 2 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 ESVPEFPLS(1)PPKKK;ESVPEFPLS(1)PPKKK 55.261 0.024086 584020000.0 237300.0 149457.0 231510.0 371010.0 348390.0 247720.0 222589.0 215304.0 212253.0 293160.0 True False 312756.4638533738 197766.05245906996 228440.02613405348 285479.37654736 300022.0621491416 232230.02923968516 242398.9897879703 182033.7139937249 223472.2602569122 282896.5576309596 1.105550617061119 0.6990754999467228 0.8075037322725396 1.0091299057790928 1.0605362775057954 0.8209008663252478 0.8568467280686439 0.6434638707452534 0.7899433705673903 1.0 18.10991509613754 -6.973026680218926 24.963767877095208 0.7994265997582571 0.9221267612640444 0.1333157193708937 0.13827596344454826 426.91496525547853 395108.00069155934 0.04991568955176716 0.044020417877026076 1.0640776462295087e-07 6.973026680218926 0.12270016150578722 ESVPEFPLS(ph)PPKKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ESVPEFPLSPPKKK 14 2 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 ESVPEFPLS(1)PPKKK;ESVPEFPLS(1)PPKKK;ESVPEFPLS(1)PPKKK 94.48700000000001 0.009653700000000001 470093000.0 266891.0 171163.0 162859.0 361545.0 301734.0 369636.0 379975.0 448160.0 355106.0 297436.0 True False 312070.37496246904 188154.931463141 166742.1762061967 341288.8057947057 242611.38871564265 350251.6374530115 343981.0172192285 436396.2748647708 360298.7534554502 351358.79229791975 0.8881814879926563 0.5355065408569682 0.47456383577506933 0.9713398761495183 0.6904947137623658 0.9968489337134064 0.9790021617775952 1.2420246324581716 1.0254439659786574 1.0 18.422585475021897 -6.736905338409384 1.084010832535878 1.0990428981005906 0.6590351053737787 0.5398775371614153 0.15430119239696827 0.3595768015797208 0.9013800659310343 0.08196947049352395 0.0759747727139371 1.832713848819032e-07 6.736905338409384 -0.4400077927268119 ESVPEFPLS(ph)PPKKK ddPTM_PC-9_Lapatinib_30min_R1 2 ESVPEFPLSPPKKK 14 2 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 ESVPEFPLS(1)PPKKK;ESVPEFPLS(1)PPKKK 61.443999999999996 0.016630000000000002 360570000.0 1052060.0 794280.0 990770.0 988920.0 888340.0 994330.0 657634.0 631995.0 1044170.0 834000.0 True False 1037057.4314758251 792440.8934604172 909312.7150828005 1061648.4757404127 836089.5877436379 951804.82379644 691683.0706921242 661359.7949111799 926564.5790024439 978155.7887648552 1.0602170363734662 0.8101377127881179 0.9296195202514879 1.085357248747652 0.8547611713256756 0.9730605643077681 0.7071297625969497 0.676129306300275 0.9472566534339515 1.0 19.899704732844747 -7.2417025430246955 24.776393462775356 0.8056396981524788 0.9463334351333693 0.17749083951389188 0.12022229108047401 1051.0884027531058 1319472.4340135192 0.04488599363649939 0.03471675030798561 5.731884848261351e-08 7.2417025430246955 0.1406937369808905 ESVS(ph)PEDSEK ddPTM_PC-9_AZD4547_30min_R2 2 ESVSPEDSEK 10 0 P35251-2;P35251;A0A1W2PP02 P35251-2 RFC1 Replication factor C subunit 1 1 ES(0.007)VS(0.993)PEDSEK;ES(0.007)VS(0.984)PEDS(0.009)EK 135.1 0.00011277 182003000.0 77993.0 93658.0 76777.0 82068.0 68840.0 82629.0 81134.0 84373.0 76384.0 82579.0 True False 102793.15164482166 123931.11691798674 75758.88681479938 63148.49053796047 59282.75426489536 77462.19556776175 88354.76882261562 71335.09154865929 80421.50229897327 79687.93434509137 1.2899462445553218 1.5552055394145208 0.9506945742466216 0.7924473266491479 0.7439363907736563 0.9720693126804997 1.1087596829903033 0.8951805832955864 1.0092055084613583 1.0 16.28207367994778 -5.273555667767252 23.51615080525517 0.9260454230198547 1.4225758635302146 0.7376395277283447 0.1164651064731847 147.24063953591804 285775.9929026091 0.03205621901586788 0.06766769190522368 5.326529446145349e-06 5.273555667767252 0.4965304405103599 ESVS(ph)PEDSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ESVSPEDSEK 10 0 P35251-2;P35251;A0A1W2PP02 P35251-2 RFC1 Replication factor C subunit 1 1 ES(0.072)VS(0.891)PEDS(0.036)EK;ES(0.026)VS(0.969)PEDS(0.005)EK;ESVS(0.923)PEDS(0.077)EK;ES(0.037)VS(0.869)PEDS(0.094)EK 150.09 0.00015919 75427600.0 208188.0 232537.0 196584.0 232201.0 239075.0 183269.0 242708.0 186935.0 179367.0 159034.0 True False 243430.11649956953 255621.73657650582 201271.3081089715 219191.53077579945 192229.96996424728 173658.05101336414 219716.94118624832 182028.1543240047 181989.90304597467 187865.60528754906 1.2957673445704596 1.3606627790395613 1.0713579412309324 1.166746464528739 1.023231312991104 0.9243738402650198 1.1695432000442405 0.968927516270956 0.9687239064724968 1.0 17.519341434631933 -5.410759396188977 1.0233852692429433 1.011626242130175 1.3789435861724204 0.6820256415069252 0.07920152605179742 0.4766023234441417 0.7619283050046255 0.02800216898298878 0.15369952468000683 3.883654650435638e-06 5.410759396188977 0.3673173440422455 ESVS(ph)PEDSEK ddPTM_PC-9_Lapatinib_30min_R1 4 ESVSPEDSEK 10 0 P35251-2;P35251;A0A1W2PP02 P35251-2 RFC1 Replication factor C subunit 1 1 ES(0.003)VS(0.99)PEDS(0.007)EK;ES(0.023)VS(0.934)PEDS(0.043)EK;ES(0.002)VS(0.996)PEDS(0.001)EK;ES(0.038)VS(0.956)PEDS(0.006)EK 166.11 0.00011921 187600700.0 221119.0 319581.0 310695.0 253888.0 286762.0 280749.0 334868.0 302672.0 270874.0 254314.0 True False 217965.80251174147 318841.02982949774 285150.8564173826 272559.77046553936 269895.222955784 268742.0197278837 352205.826518292 316735.24607845984 240365.31769032642 298271.8360478963 0.730762265052543 1.068961233665717 0.9560099947605957 0.9137965356600812 0.9048632500201742 0.90099696735943 1.1808215994678593 1.061901285334894 0.8058599191769776 1.0 18.18626823383208 ESVSESS(ph)QQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESVSESSQQQK 11 0 Q8IVL1-4;Q8IVL1-11 Q8IVL1-4 NAV2 Neuron navigator 2 1 ESVSES(0.083)S(0.917)QQQK 58.699 0.040221 1272700.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ESVSTASDQPS(ph)HSLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ESVSTASDQPSHSLER 16 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 ESVSTAS(0.006)DQPS(0.925)HS(0.069)LER 160.09 2.6448e-05 6882000.0 7010.2 12929.0 12686.0 16146.0 20024.0 16569.0 8529.7 9861.7 12179.0 6718.7 True False 8196.888402238757 14212.50567521572 12988.482351922908 15241.391966038267 16100.440943486732 15700.092471942506 7721.7050663197815 9602.84082433486 12357.094834595673 7936.747124800065 1.0327768131387007 1.7907217467979677 1.6364994559720336 1.9203575125145762 2.028594421658901 1.9781520344631123 0.9729055171975508 1.2099214795856013 1.5569470263180347 1.0 12.954332124715208 -7.261244357181066 24.99999996765851 1.2024369579915928 1.7517035974555315 0.4397815812142174 0.30123755647382094 17.83732303757075 2286785.538737802 0.12411769742537046 0.08995466832641265 5.4796856190080035e-08 7.261244357181066 0.5492666394639387 ESVSTASDQPSHS(ph)LER ddPTM_PC-9_AZD4547_30min_R2 5 ESVSTASDQPSHSLER 16 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 ESVSTASDQPS(0.216)HS(0.784)LER;ESVSTASDQPS(0.013)HS(0.987)LER;ESVSTASDQPS(0.001)HS(0.999)LER;ESVSTASDQPS(0.089)HS(0.911)LER;ESVSTAS(0.002)DQPS(0.069)HS(0.929)LER 178.47 6.9421e-06 54638900.0 87439.3 79950.8 143310.0 199347.0 187932.0 163333.9 134156.0 187156.0 139629.0 169833.0 True False 115243.17854957559 105793.3325768924 141409.61576290938 153390.62903044815 161840.88574245083 153120.60541269075 146095.62410539103 158235.34061703246 147009.50388174687 163887.19836314186 0.7031859699878409 0.6455252980923815 0.8628472338002474 0.9359524756202412 0.9875138958922417 0.9343048568894659 0.8914401220141174 0.9655137326004806 0.897016395118322 1.0 17.322343640775856 -5.410054817979075 3.1223344478498105 0.9412774685879376 0.672653734597735 0.8951376822215722 0.03638575649243826 0.07053817945827565 1.2881492743201117 0.009774219065862875 0.023263034460389312 3.8899604162409246e-06 5.410054817979075 -0.26862373399020256 ESVSTASDQPSHS(ph)LER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESVSTASDQPSHSLER 16 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 ESVSTASDQPS(0.052)HS(0.948)LER;ESVSTASDQPS(0.074)HS(0.926)LER 113.63 0.00012053 34222000.0 27145.5 43488.0 58957.0 64956.0 69175.0 61747.0 67654.0 65078.0 62724.1 46812.8 True False 31740.697001936045 47805.20123782047 60362.7584756676 61316.725910193345 55620.655326892505 58508.87862061889 61245.32334745635 63369.77145584067 63641.32130016115 55299.59007007907 0.5739770758103679 0.8644765933569987 1.0915588777271616 1.108809772956526 1.0058059247167395 1.058034581205264 1.1075185778021588 1.1459356457350691 1.15084616756672 1.0 15.754981165505706 -4.870174265799758 1.981313282715403 1.0885717230869647 0.4747772730828845 0.9108031117925462 0.04979223152970324 0.16969801764074122 0.8492359928141036 0.014343540806547112 0.18050688734932574 1.348421703857532e-05 4.870174265799758 -0.6137944500040802 ESVSTASDQPSHS(ph)LER ddPTM_PC-9_Lapatinib_30min_R1 4 ESVSTASDQPSHSLER 16 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 ESVSTASDQPS(0.037)HS(0.963)LER;ESVSTASDQPS(0.013)HS(0.987)LER;ESVSTASDQPS(0.111)HS(0.889)LER;ESVSTASDQPS(0.25)HS(0.75)LER 123.61 2.1782e-05 75235000.0 151582.0 142998.0 196340.0 136119.0 143050.0 141805.0 129031.0 135474.0 165029.0 105498.0 True False 149420.4128832656 142666.89691677078 180197.68309431765 146129.64533967242 134636.08024712102 135740.33071360036 135711.5938264683 141768.61661215205 146441.69618758853 123733.18873275124 1.2076017308985358 1.1530204497106598 1.4563407355767974 1.1810060569544913 1.0881161443104703 1.097040592777279 1.0968083439568423 1.145760632730117 1.1835280225735145 1.0 16.916872998179002 -5.99580513030425 24.99982380645685 1.1110223954822984 1.2701046705648857 0.4462631285362427 0.08485942136691499 118.42719198429313 705767.2866280035 0.023904676247593015 0.0352955929294921 1.0097058435550412e-06 5.99580513030425 0.15908227508258732 ESVSTEDLS(ph)PPSPPLPK ddPTM_PC-9_Lapatinib_30min_R1 2 ESVSTEDLSPPSPPLPK 17 0 Q13127;Q13127-4 Q13127 REST RE1-silencing transcription factor 1 ES(0.074)VS(0.007)T(0.005)EDLS(0.708)PPS(0.206)PPLPK;ES(0.002)VS(0.015)T(0.003)EDLS(0.565)PPS(0.415)PPLPK 103.88 0.006150500000000001 0.0 24300.0 26234.0 57143.0 21350.0 33440.0 41425.0 24986.0 34112.0 59003.0 25434.0 True False 23953.47754392577 26173.256784812143 52444.92311835888 22920.150221512165 31473.124945569536 39653.3493163915 26279.652822563057 35696.96805197849 52357.46081086523 29830.23301132529 0.8029933100030306 0.8774070512582068 1.7581130894434427 0.76835304011237 1.0550747268256506 1.3293006897176023 0.880973769550703 1.1966707748620617 1.7551810872877627 1.0 14.864487626514245 -8.01087846213534 24.684617732622883 1.410369045778635 1.0815192780217315 0.12302104646536982 0.3262977681714343 820.8725170638302 1862653.4494005651 0.1909895053070398 0.08189371616404251 9.7526252799357e-09 8.01087846213534 -0.32884976775690355 ESVSTEDLSPPS(ph)PPLPK ddPTM_PC-9_AZD4547_30min_R2 2 ESVSTEDLSPPSPPLPK 17 0 Q13127;Q13127-4 Q13127 REST RE1-silencing transcription factor 1 ESVSTEDLS(0.003)PPS(0.997)PPLPK;ESVSTEDLS(0.036)PPS(0.964)PPLPK 198.85 2.1973e-12 25712000.0 48455.0 58512.0 76567.0 101732.0 90969.0 81639.0 67738.0 82411.0 78928.0 82063.0 True False 63862.68207338903 77424.85973547633 75551.67155201099 78279.25914373201 78339.52458923985 76534.10042426377 73766.55077410622 69676.27356638455 83099.97294529437 79189.99934803323 0.806448826861559 0.9777100691111353 0.9540557163028616 0.9884993027932908 0.9892603262306441 0.9664616877682115 0.9315134661121611 0.8798620298020629 1.0493745880723795 1.0 16.273030628011078 -4.758938620987692 24.962089917721205 0.9662457601269513 0.8064486125595639 0.5722580525736878 0.04245373948812693 49.28839990967659 491882.09031895985 0.010388553867373482 0.0684219841158292 1.7420530610480886e-05 4.758938620987692 -0.1597971475673874 ESVSTEDLSPPS(ph)PPLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESVSTEDLSPPSPPLPK 17 0 Q13127;Q13127-4 Q13127 REST RE1-silencing transcription factor 1 ESVSTEDLS(0.02)PPS(0.98)PPLPK;ESVSTEDLS(0.06)PPS(0.94)PPLPK 153.79 2.3708e-05 19462500.0 86206.0 75353.0 82683.0 90580.0 103611.0 88183.0 99245.0 92194.0 87662.0 71834.0 True False 100798.9731538894 82833.54784937181 84654.47629702381 85505.09626432207 83309.16832778681 83558.52824270065 89843.79512842283 89774.00518761764 88943.89090978948 84856.93556236889 1.1878695888069548 0.9761553054021151 0.997614110573245 1.0076382760897227 0.9817602742271493 0.9846988662616277 1.0587678488859482 1.057945406496971 1.0481628911100227 1.0 16.372744959087818 -10.565569004659936 14.911321455463726 0.9999993792269031 1.028424052756176 0.021348790267133544 0.05983935173129312 0.0 0.0 0.05719484918669753 0.013871788496354488 2.7191364106331458e-11 10.565569004659936 0.028424673529273026 ESVSTEDLSPPS(ph)PPLPK ddPTM_PC-9_Lapatinib_30min_R1 2 ESVSTEDLSPPSPPLPK 17 0 Q13127;Q13127-4 Q13127 REST RE1-silencing transcription factor 1 ESVSTEDLS(0.061)PPS(0.939)PPLPK;ESVSTEDLSPPS(1)PPLPK 147.75 7.7956e-05 23501000.0 106796.0 102015.0 105285.0 84069.0 104762.0 108458.0 102328.0 93224.0 107770.0 77864.0 True False 105273.06945601222 101778.79053528313 96628.87371185285 90251.7147059627 98600.10513001651 103819.50416794667 107626.04314525073 97555.52737094405 95631.80773158903 91322.68865274166 1.1527591993739634 1.1144962115855046 1.058103688550916 0.9882726410864732 1.0796890300169275 1.1368423958992784 1.1785246879283553 1.0682507141451236 1.0471856352722264 1.0 16.47868571446113 -8.418187625000135 2.3249579067918873 1.0029620887545199 1.0968336192131565 0.27753887248875786 0.050907986528592485 0.42759055990010025 4.7738485447031955 0.05435102505721995 0.015050937786817377 3.817792979490254e-09 8.418187625000135 0.09387153045863661 ESWVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 ESWVSPR 7 0 Q8IYH5-4;Q8IYH5-2;Q8IYH5 Q8IYH5-4 ZZZ3 ZZ-type zinc finger-containing protein 3 1 ES(0.003)WVS(0.997)PR 74.165 0.034581 10336000.0 78736.0 60805.0 95478.0 75423.0 62627.0 60001.0 57688.0 48900.0 79440.0 73495.0 True False 77613.2102015861 60664.209758348086 87628.16739573833 80969.85902375237 58943.40298941936 57434.89709916245 60674.80237044815 51172.07251822665 70492.63065971456 86198.51282406824 0.9004008034337576 0.7037732760211787 1.0165856060021363 0.9393417168230317 0.6838099760459122 0.6663096057862097 0.7038961622723798 0.5936537747776368 0.8177940471384989 1.0 16.395375358378324 -6.265497586640981 24.831638194470443 0.7180125086777359 0.8857616506824533 0.22383100524577704 0.12739720693573325 412.4415695695077 2523672.0620264285 0.03793071438972637 0.04457806127751919 5.426282666866516e-07 6.265497586640981 0.16774914200471736 ESYDAPPT(ph)PSGAR ddPTM_PC-9_AZD4547_30min_R2 4 ESYDAPPTPSGAR 13 0 Q96S55-2;Q96S55 Q96S55-2 WRNIP1 ATPase WRNIP1 1 ESYDAPPT(0.999)PS(0.001)GAR;ESYDAPPT(0.991)PS(0.009)GAR;ESYDAPPT(0.95)PS(0.05)GAR;ESYDAPPT(0.794)PS(0.206)GAR 153.0 0.00017087 154271000.0 114152.0 124247.0 147611.0 209110.0 181573.0 182216.0 140272.0 217210.0 163437.0 178688.0 True False 150449.96149089912 164407.4129674894 145653.58169268596 160902.92021729454 156364.72312812126 170822.00471475202 152755.93625712916 183645.18548924784 172075.94615675157 172432.18750839453 0.8725166899803712 0.9534612727654779 0.8447006547753452 0.9331373831203138 0.9068186478844557 0.9906619360520256 0.8858899168677108 1.0650284505629637 0.9979340205747513 1.0 17.39566957847142 -7.338634244165167 0.8926681605979819 1.0206214244024363 0.9002713186136266 0.4627812045680433 0.04794917067777848 0.5122680176326803 0.7806678964062108 0.03633145486410108 0.01995134819693804 4.5852788897017505e-08 7.338634244165167 -0.12035010578880967 ESYDAPPT(ph)PSGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ESYDAPPTPSGAR 13 0 Q96S55-2;Q96S55 Q96S55-2 WRNIP1 ATPase WRNIP1 1 ESYDAPPT(0.984)PS(0.016)GAR;ESYDAPPT(0.679)PS(0.321)GAR;ESYDAPPT(0.983)PS(0.017)GAR 141.59 0.00019026 108343000.0 90233.0 92365.0 112472.0 95946.0 125470.0 98808.0 113809.0 111404.0 103721.0 87889.0 True False 105507.66471701358 101534.38678098095 115153.75903243547 90570.45668112916 100885.05419393108 93626.33453845707 103028.18761419394 108479.76304229486 105237.72340414638 103822.57997105889 1.0162304264296305 0.9779605439325839 1.1091398332090687 0.8723579851933574 0.9717062918495508 0.9017916388184143 0.9923485588868396 1.0448571310068984 1.0136304013393038 1.0 16.66376071841775 -10.074776902515332 8.269416647286087 0.9999999977533047 0.9873597180851073 0.0022123770432820322 0.06369110852306148 0.0 0.0 0.06268516217911839 0.015203385102890425 8.418274781587876e-11 10.074776902515332 -0.012640279668197474 ESYDAPPT(ph)PSGAR ddPTM_PC-9_Lapatinib_30min_R1 3 ESYDAPPTPSGAR 13 0 Q96S55-2;Q96S55 Q96S55-2 WRNIP1 ATPase WRNIP1 1 ESYDAPPT(0.831)PS(0.169)GAR;ESYDAPPT(0.943)PS(0.057)GAR;ESYDAPPT(0.643)PS(0.357)GAR 169.58 1.3162e-18 80028000.0 94948.0 83729.0 91538.0 81881.0 93168.0 100615.0 92902.0 77728.0 121223.0 76527.0 True False 93594.02410866921 83535.13064479447 84012.09898689846 87902.8018870089 87688.04141533571 96311.93099502065 97712.0109870229 81339.52664001459 107569.58920521874 89754.58998418217 1.042777022603119 0.9307059467322643 0.9360200854541731 0.979368318684319 0.9769755667179734 1.07305855903296 1.0886575383414163 0.9062436434097622 1.1984856621168476 1.0 16.45369809874245 -6.699532448099785 6.792120925961233 1.049533563108255 0.9684783843024569 0.22282873723308183 0.07444735814448916 0.3281433483379144 28.50751961196174 0.023557705878773687 0.0234054592274436 1.997411527242288e-07 6.699532448099785 -0.08105517880579804 ESYDDVSSFR ddPTM_PC-9_Lapatinib_30min_R1 1 ESYDDVSSFR 10 0 H7C2Q8;Q99848 H7C2Q8 EBNA1BP2 Probable rRNA-processing protein EBP2 0 136.99 0.00053632 5835500.0 28283.0 20518.0 29094.0 23665.0 27305.0 23639.0 19304.0 21450.0 25536.0 16935.0 False True 27879.679233533025 20470.49183162216 26702.00362608775 25405.403044125756 25698.973583695475 22628.015075200434 20303.46666480257 22446.64530707488 22659.866773998852 19862.19218553092 1.403655697876221 1.0306260074622764 1.3443633701993605 1.2790835375479308 1.2938639070473046 1.1392506357724372 1.0222168064405854 1.130119228401519 1.1408542703813915 1.0 14.277737241119512 -6.906312425494507 4.511498468608726 1.083542997068198 1.260987794966173 0.46897108671772525 0.09913859455954134 0.20937307872369848 7.569282612409216 0.03485570843827213 0.03051080016013277 1.2407594011607766e-07 6.906312425494507 0.17744479789797496 ESYDYLK ddPTM_PC-9_Lapatinib_30min_R1 1 ESYDYLK 7 0 F8VXU5;Q9UBQ0;Q9UBQ0-2 F8VXU5 VPS29 Vacuolar protein sorting-associated protein 29 0 87.323 0.029988 0.0 24202.0 19700.0 20748.0 18065.0 23687.0 19469.0 17344.0 21303.0 23278.0 18180.0 False True 23856.87504189676 19654.38586036439 19042.179529596087 19393.560363073408 22293.77723043379 18636.35625445565 18241.987455156224 22292.815150424984 20656.186511792985 21322.388776672706 1.118865024541568 0.9217722304110149 0.8930603287014806 0.9095397596488115 1.0455572058053744 0.874027598391994 0.8555320722373035 1.0455120851568915 0.9687557397129648 1.0 14.380081453819463 -7.794332266434393 24.998818945174996 1.0053503904008383 0.9422698499277864 0.10706752951047604 0.07805662302842895 451.4503128901367 343099.5417853782 0.04294517406441926 0.020632449949632727 1.6057122978537663e-08 7.794332266434393 -0.0630805404730519 ESYS(ph)IYVYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ESYSIYVYK 9 0 Q16778;P33778;P23527;P06899;Q6DRA6;Q6DN03;Q8N257 Q16778;Q8N257 HIST2H2BE;HIST1H2BB;HIST1H2BO;HIST1H2BJ;HIST2H2BD;HIST2H2BC;HIST3H2BB Histone H2B type 2-E;Histone H2B type 1-B;Histone H2B type 1-O;Histone H2B type 1-J;Putative histone H2B type 2-D;Putative histone H2B type 2-C;Histone H2B type 3-B 1 ES(0.005)YS(0.995)IYVYK;ESYS(1)IYVYK 116.77 0.0018987000000000001 5775100.0 30834.0 32377.0 28954.0 37393.0 35924.0 38170.0 38373.0 35756.0 26232.0 23840.0 True False 36053.58720074033 35591.174587861344 29644.373168656493 35297.99143974169 28884.95008259177 36168.298005555305 34738.03164353833 34817.44288661356 26615.593373931668 28162.003282663834 1.2802209714581794 1.263801237100587 1.0526372314893233 1.2533906443179301 1.0256710004850036 1.2842942187930233 1.2335071228729886 1.236326923803987 0.9450887817457178 1.0 14.781462342188322 -8.262780591292863 24.989737895582376 0.9725443635028966 1.2000949861701098 0.5274731876472776 0.08747163404689152 94.63045809498833 1763068.931149149 0.06997810365501947 0.02181670086420707 5.4603365156195526e-09 8.262780591292863 0.22755062266721315 ESYS(ph)VYVYK ddPTM_PC-9_AZD4547_30min_R2 1 ESYSVYVYK 9 0 U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 U3KQK0 HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 1 ESYS(1)VYVYK 146.11 0.00045596 14468000.0 15289.0 33173.0 36359.0 49535.0 33913.0 30312.0 16555.0 31504.0 21010.0 30752.0 True False 20150.583969044386 43895.52351662838 35876.85590345144 38115.47105812098 29204.765330990653 28416.5858481888 18028.362928715454 26635.780689900326 22120.545707234887 29675.3818401803 0.67903368784157 1.4791898467568863 1.2089770604021135 1.2844138371460767 0.9841411810057171 0.9575811358124767 0.6075191559727515 0.8975716246331709 0.7454173909662652 1.0 14.856978973035515 -6.657567912584124 2.1783340939132194 0.8083460883711179 1.185566172453874 0.3283313381894347 0.21467971618962156 0.3183270311484263 3.090341590007992 0.07797456710677644 0.07688750689332262 2.2000476513772415e-07 6.657567912584124 0.3772200840827561 ESYS(ph)VYVYK ddPTM_PC-9_Lapatinib_30min_R1 2 ESYSVYVYK 9 0 U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 U3KQK0 HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 1 ES(0.002)YS(0.998)VYVYK;ESYS(1)VYVYK 155.53 7.8345e-05 20358000.0 81976.0 125525.0 108670.0 72118.0 92137.0 99940.0 106189.0 116915.0 78305.0 66234.0 True False 80807.00720744264 125234.35457473292 99735.5720783306 77421.79829859568 86717.68280831163 95665.79917151867 111686.94683323258 122347.29771919156 69485.46631179436 77682.45864874257 1.0402220605919332 1.6121317058334386 1.2838879434713284 0.9966445404190215 1.116309708996515 1.2314980863838452 1.437737022951969 1.574966856705841 0.8944807813818996 1.0 16.245301242307264 -8.291847571796463 24.8230337031172 0.9472401891063112 1.2852801238566232 0.31852357551502586 0.19858753654377673 922.9259659444166 753400.7344200006 0.1998380894678799 0.05162546283297187 5.1068420791070985e-09 8.291847571796463 0.3380399347503119 ESYSIYVYK ddPTM_PC-9_AZD4547_30min_R2 1 ESYSIYVYK 9 0 Q16778;P33778;P23527;P06899;Q6DRA6;Q6DN03;Q8N257 Q16778;Q8N257 HIST2H2BE;HIST1H2BB;HIST1H2BO;HIST1H2BJ;HIST2H2BD;HIST2H2BC;HIST3H2BB Histone H2B type 2-E;Histone H2B type 1-B;Histone H2B type 1-O;Histone H2B type 1-J;Putative histone H2B type 2-D;Putative histone H2B type 2-C;Histone H2B type 3-B 0 138.1 0.004181300000000001 15877000.0 26235.0 22388.0 36660.0 52029.0 46287.0 33062.0 25615.0 37377.0 27773.0 38568.0 False True 34577.18427810054 29624.48317879829 36173.864446781525 40034.5178900369 39860.84902177821 30994.62791346059 27894.685377169822 31601.24348801437 29241.02408029675 37217.74605918557 0.9290510022588183 0.795977357997121 0.9719520464580522 1.0756835684345838 1.071017276500018 0.8327916436468598 0.7494995890619024 0.8490907385353333 0.7856742327650946 1.0 15.183703066658016 -6.855660787103839 10.61456739139655 0.8276092294711266 0.9651850560956708 0.293407687430581 0.09562578580725091 0.4822894246607428 50.615203307599295 0.03586886000157729 0.03164015917576936 1.394245376202947e-07 6.855660787103839 0.13757582662454426 ESYSIYVYK ddPTM_PC-9_Lapatinib_30min_R1 1 ESYSIYVYK 9 0 Q16778;P33778;P23527;P06899;Q6DRA6;Q6DN03;Q8N257 Q16778;Q8N257 HIST2H2BE;HIST1H2BB;HIST1H2BO;HIST1H2BJ;HIST2H2BD;HIST2H2BC;HIST3H2BB Histone H2B type 2-E;Histone H2B type 1-B;Histone H2B type 1-O;Histone H2B type 1-J;Putative histone H2B type 2-D;Putative histone H2B type 2-C;Histone H2B type 3-B 0 152.47 0.00047087 70069000.0 20665.0 16509.0 18439.0 18449.0 18012.0 18961.0 18515.0 18143.0 18694.0 21518.0 False True 20370.313310503123 16470.774424809937 16923.016596598347 19805.80100405986 16952.569572954508 18150.082230249816 19473.616105409223 18985.990014277828 16588.48486345296 25237.357629067283 0.8071492114943717 0.6526346643295026 0.6705542174949075 0.7847810890173544 0.6717252187063071 0.7191752202039308 0.7716186611779184 0.7522970626849855 0.6572987991558621 1.0 14.623273246486368 -10.594600232707108 4.107821126206396 1.0000413459113924 0.720132016709779 0.7093569766181201 0.05361245855644535 74078055.48425312 172033283.97835362 45934.267253562306 0.013023717284238472 2.5433127432095973e-11 10.594600232707108 -0.2799093292016134 ESYSVYVYK ddPTM_PC-9_AZD4547_30min_R2 2 ESYSVYVYK 9 0 U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 U3KQK0 HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 0 ; 133.23 0.0054181 53747000.0 146145.0 172940.0 179074.0 251033.0 238824.0 191477.0 199927.0 258808.0 203585.0 247861.0 False True 192616.06999515885 228839.47297397608 176699.36175512685 193161.22027118792 205667.41000231542 179503.91292074576 217720.11569008091 218815.1704161927 214346.08747298527 239183.4618330163 0.8053068072475343 0.9567529093367593 0.7387607838809853 0.8075860211691459 0.8598730381530316 0.7504863068085565 0.9102640877490107 0.9148423922760867 0.8961576433015631 1.0 17.867758113319198 -8.168351755771761 0.8550855727894803 0.9889524981832238 0.8248334377693319 0.4277843697578615 0.062411981928526476 0.560459698722971 0.8451870294513781 0.05879881322724424 0.022387760876035834 6.786537359912455e-09 8.168351755771761 -0.1641190604138919 ESYSVYVYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ESYSVYVYK 9 0 U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 U3KQK0 HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 0 ;; 156.75 0.00043247 42738600.0 156853.0 149264.0 178101.0 186336.0 205819.0 167971.0 175443.0 175039.0 162983.0 129303.0 False True 183405.114912036 164081.94346859018 182347.6032918037 175896.19802946286 165490.2444340539 159162.30506395426 158823.76894267605 170444.41171915107 165366.31804145692 152744.61033801507 1.2007305168160827 1.0742241124284926 1.1938071195329178 1.1515705702493506 1.0834440840029214 1.0420158505870498 1.0397994966317183 1.1158784021378387 1.0826327532965696 1.0 17.220761949238266 -6.339179967961183 3.780960875098558 1.0624770330654723 1.1524422819757276 0.5426751140119278 0.04280193183829923 0.2025420716101454 5.559188616769064 0.013482997524914662 0.015682406034358425 4.579520759211454e-07 6.339179967961183 0.08996524891025537 ESYSVYVYK ddPTM_PC-9_Lapatinib_30min_R1 2 ESYSVYVYK 9 0 U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 U3KQK0 HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 0 ; 152.47 0.00047087 242780000.0 312690.0 250814.0 323260.0 249601.0 278382.0 324626.0 257820.0 236021.0 237460.0 233546.0 False True 308230.98325967713 250233.2555929668 296682.81061968533 267957.4901845278 262008.11808007013 310742.5027201667 271168.6580770515 246987.39729702217 210714.75423534514 273914.11491951655 1.1252833149917951 0.913546407298113 1.083123484552298 0.9782536773004964 0.9565338323549163 1.134452318426421 0.9899769427973008 0.9016964947921497 0.7692730777939607 1.0 18.063364085130374 -7.7494971572823435 3.750055567583911 0.8717780781378013 1.0253053059183925 0.35158953122566583 0.08496399910612913 0.22428868971082738 6.774684159123276 0.04482666323227501 0.02208545440338997 1.780339562204981e-08 7.7494971572823435 0.15352722778059125 ESYTEEIVS(ph)EAESHVSGISR ddPTM_PC-9_AZD4547_30min_R2 5 ESYTEEIVSEAESHVSGISR 20 0 Q5QJE6;J3KP30;E9PRB3 Q5QJE6 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 ESYTEEIVS(1)EAESHVSGISR;ESYTEEIVS(1)EAESHVSGISR;ESYTEEIVS(1)EAESHVSGISR;ESYTEEIVS(1)EAESHVSGISR;ESYTEEIVS(1)EAESHVSGISR 183.75 1.0854e-11 6795500.0 1634.4 1694.38 15105.14 42133.4 24869.8 19171.07 7652.09 29261.9 11454.199999999999 18118.600000000002 True False 2154.1052023681154 2242.0551995931874 14904.835974076852 32420.19558454095 21417.05755399615 17972.299962280173 8333.111185937438 24740.145726567876 12059.645627787238 17484.27332887264 0.12320244381051487 0.12823267844313388 0.8524710002939477 1.8542489570329403 1.2249326666970544 1.02791232007347 0.4766060921832285 1.4149942214477542 0.6897424560317615 1.0 14.093770216384778 -5.333179847720286 4.10041677631883 1.1067044849262873 0.11639930451581126 0.5335297744296779 0.35673920060052705 0.16338168418103635 5.27800105097751 0.09810389814385154 0.22652463376454177 4.6432295245290574e-06 5.333179847720286 -0.990305180410476 ESYTEEIVS(ph)EAESHVSGISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ESYTEEIVSEAESHVSGISR 20 0 Q5QJE6;J3KP30;E9PRB3 Q5QJE6 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 ESYTEEIVS(1)EAESHVSGISR;ESYTEEIVS(1)EAESHVSGISR;ESYTEEIVS(1)EAESHVSGISR 169.19 3.7621e-21 3703100.0 480.31 1784.84 14081.9 12819.400000000001 15175.9 16916.6 9427.3 10164.4 12679.6 7075.8 True False 561.6169964450798 1962.0271196033727 14417.665901903152 12101.170579055559 12202.291336109682 16029.46371602769 8534.277896258545 9897.59527007202 12865.015162553516 8358.586527998019 0.06719042682203277 0.23473192662794645 1.7248928217240522 1.4477532222130305 1.4598510519974572 1.917724206399636 1.021019267752033 1.1841230855143894 1.5391376424064895 1.0 13.029043281817842 -5.248294315178103 20.49803568494966 1.4254990026351655 0.15095696917028292 0.7690368392890257 0.2763081775542149 31.33870780869673 48865.139983266316 0.07062105013745892 0.18283801147009995 5.6455425477609285e-06 5.248294315178103 -1.2745420334648825 ESYTEEIVS(ph)EAESHVSGISR ddPTM_PC-9_Lapatinib_30min_R1 3 ESYTEEIVSEAESHVSGISR 20 0 Q5QJE6;J3KP30;E9PRB3 Q5QJE6 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 ESYTEEIVS(1)EAESHVSGISR;ESYTEEIVS(1)EAESHVSGISR;ES(0.001)Y(0.001)T(0.001)EEIVS(0.937)EAES(0.049)HVS(0.009)GIS(0.003)R 114.75 1.1625e-05 3524030.0 6596.1 1755.1299999999999 16607.699999999997 5029.66 8797.3 16759.2 7559.6 6426.1 16370.099999999999 6170.29 True False 6502.038404423409 1751.0661043198647 15242.279013575913 5399.557974853902 8279.86011015726 16042.448083603324 7950.999098593116 6724.680065631419 14526.326953204845 7236.816405105384 0.8984666793310373 0.24196635734527322 2.1062133071142837 0.7461233880473541 1.1441301874559147 2.2167825167273554 1.098687413568195 0.9292318181358497 2.0072813983448445 1.0 12.82113945618642 -5.24344940641444 24.987866301149033 1.388582371517534 0.5702164974837626 0.2909812115478194 0.5213198366641281 1028.551544407776 1428641.2467506023 0.12828363207641352 0.3378941469788658 5.708875784380063e-06 5.24344940641444 -0.8183658740337715 ET(ph)DVSPFPPR ddPTM_PC-9_AZD4547_30min_R2 2 ETDVSPFPPR 10 0 Q9H8V3-2;Q9H8V3-4;Q9H8V3;Q9H8V3-3 Q9H8V3-2 ECT2 Protein ECT2 1 ET(0.857)DVS(0.143)PFPPR;ET(0.608)DVS(0.392)PFPPR 115.57 0.0027206999999999995 8725400.0 55015.0 49502.0 70053.0 95322.0 79276.0 79523.0 62052.0 84604.0 66530.0 81880.0 True False 72508.62561691253 65502.553435629525 69124.051448183 73346.9856102193 68269.89580336779 74550.41423876732 67574.50778934773 71530.39580651102 70046.63997631309 79013.4061223325 0.917674976631827 0.8290055656405345 0.8748395347134093 0.9282853278930899 0.8640292724207957 0.9435160170584805 0.8552283859871261 0.9052944217562788 0.8865158890614511 1.0 16.26980983417254 -14.522878745279964 0.30435124557970367 1.950221963710445 0.8832184986417879 0.49457463585502026 0.03348612690066209 229.69793381803456 2.1053817532210717 139.5527473652935 0.03150434940029934 3.000000000002578e-15 14.522878745279964 -1.067003465068657 ET(ph)DVSPFPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ETDVSPFPPR 10 0 Q9H8V3-2;Q9H8V3-4;Q9H8V3;Q9H8V3-3 Q9H8V3-2 ECT2 Protein ECT2 1 ET(0.907)DVS(0.093)PFPPR;ET(0.833)DVS(0.167)PFPPR 98.04 0.012012 7711500.0 47073.0 40199.0 46043.0 49765.0 59434.0 49866.0 47784.0 43757.0 35782.0 34379.0 True False 55041.5291658704 44189.691054064235 47140.83973904989 46976.82839030686 47788.334350538884 47250.939175924046 43257.55359379865 42608.42511437379 36305.244057106676 40611.640555985716 1.3553141023690527 1.0881040620150755 1.1607716185230994 1.1567330880304214 1.1767151904306756 1.1634826500245818 1.0651515920457677 1.0491677886204913 0.8939615233484006 1.0 15.309605687387382 -7.62697098821627 1.3542906104211325 0.953411097693456 1.180610215977002 0.6380292416863045 0.0704733982227438 0.2852944044097497 0.9818514228499583 0.05185313931505673 0.022223426137390832 2.3606359233522598e-08 7.62697098821627 0.227199118283546 ET(ph)DVSPFPPR ddPTM_PC-9_Lapatinib_30min_R1 1 ETDVSPFPPR 10 0 Q9H8V3-2;Q9H8V3-4;Q9H8V3;Q9H8V3-3 Q9H8V3-2 ECT2 Protein ECT2 1 ET(0.89)DVS(0.11)PFPPR 88.134 0.024897 3627500.0 18254.0 19542.0 18760.0 15238.0 13315.0 21190.0 15154.0 12187.0 20269.0 15428.0 True False 17993.694612626387 19496.75169965691 17217.625215694177 16358.653352477868 12531.837878297207 20283.753096302597 15938.59997090854 12753.252510830835 17986.091777967682 18094.709243482204 0.9944174493496101 1.07748355816658 0.9515281502462408 0.9040572651572353 0.6925691764188602 1.1209770117532503 0.8808431103500431 0.7048056058388787 0.9939972804175538 1.0 14.143280305366755 -5.526725963575211 3.2584034627385616 0.8876467008479595 1.034996440526823 0.1542377924802668 0.12405605543317844 0.4048094853199764 8.888396776551332 0.03415227419749474 0.07133290670828535 2.973541721495965e-06 5.526725963575211 0.14734973967886356 ET(ph)HCWEFS(ph)PS(ph)MY(ph)FLSLEQIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETHCWEFSPSMYFLSLEQIPK 21 0 E5RFN6;Q8WWZ4-2;Q8WWZ4 E5RFN6 ABCA10 ATP-binding cassette sub-family A member 10 4 ET(0.995)HCWEFS(0.974)PS(0.972)MY(0.863)FLS(0.196)LEQIPK 45.70399999999999 0.045176 0.0 3641.9 3845.3 4032.2 5320.9 4574.6 4376.2 7149.6 4422.6 5387.8 4733.0 True False 4258.401739196219 4227.035971297627 4128.342940203654 5022.787223590552 3678.2399690408724 4146.70436814019 6472.338129378515 4306.51143613204 5466.586382283815 5591.0554335926145 0.7616454155704767 0.7560354250649028 0.7383834750411206 0.8983611919517468 0.6578793597611258 0.7416675469224716 1.1576236734286176 0.7702501767836754 0.977737825570293 1.0 12.448904933577161 -7.2055587467806665 24.999869630576523 0.9572576357194857 0.7596624708434891 0.5095892551772873 0.10380538359514895 253.61484658140037 113462.12572415746 0.0381511833919969 0.029551769280350856 6.229328779347464e-08 7.2055587467806665 -0.1975951648759966 ET(ph)PHSPGVEDAPIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETPHSPGVEDAPIAK 15 0 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 ET(0.547)PHS(0.453)PGVEDAPIAK 99.39200000000001 0.004342800000000001 100650000.0 74781.0 83889.0 82674.0 85108.0 98522.0 78828.0 100980.0 87312.0 75832.0 68025.0 True False 87439.94630792498 92216.94551691308 84645.26170289109 80339.67468385892 79217.32134609461 74694.12091123701 91414.44336811031 85020.15251471111 76940.89953995064 80357.39401439641 1.0881381530647907 1.1475850685301214 1.053359964457365 0.9997794934647293 0.9858124733599805 0.9295239327678446 1.1375984063362354 1.0580252577563596 0.957483757203056 1.0 16.294143157863203 -5.476665380398442 4.193225023873458 1.0135884259190757 1.116751023406285 0.3749967842952464 0.05528704827859206 0.240863218930138 8.963210747749567 0.015678962382000245 0.03298305731747339 3.336834135110243e-06 5.476665380398442 0.10316259748720924 ET(ph)QSPEQVK ddPTM_PC-9_AZD4547_30min_R2 1 ETQSPEQVK 9 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 ET(0.755)QS(0.245)PEQVK 92.11200000000001 0.017800999999999997 2991400.0 17505.0 22236.0 26121.0 31305.0 27310.0 29353.0 27240.0 28917.0 27239.0 31292.0 True False 23071.22587338098 29423.352151320298 25774.618472841797 24088.11590742865 23518.47790491419 27517.552269790358 29664.3072291277 24448.542096554356 28678.797930479344 30196.476604543535 0.7640370158255334 0.9743968654572465 0.8535637720383443 0.7977128001683552 0.7788484137707465 0.9112835457647369 0.9823764413846957 0.8096488347543067 0.9497398754848162 1.0 14.882092601891209 -6.915707517649024 9.252291778238446 0.9234349695642917 0.8407670282587928 0.30536646180773297 0.07250782309060627 0.4695376721844168 47.01846414185301 0.025777835686383074 0.02273530833457373 1.2142063012269992e-07 6.915707517649024 -0.08266794130549893 ET(ph)QSPEQVKSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETQSPEQVKSEK 12 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 ET(0.64)QS(0.36)PEQVKSEK 62.799 0.036167000000000005 176820000.0 35346.0 13661.0 29110.0 47296.0 46386.0 50888.0 33405.0 48286.0 41323.0 38119.0 True False 41329.3796846782 15017.173797596257 29804.09280028978 44646.15845570086 37296.99628468717 48219.34369679589 30240.63656874362 47018.543663245975 41927.27069956456 45029.672950162014 0.9178254465765445 0.33349506700208503 0.6618767325553615 0.9914830717317086 0.8282759753988616 1.070834863716735 0.6715713125923295 1.0441680026254068 0.9311031582656366 1.0 15.458588378994856 -5.675121166386361 5.45033053815433 0.9256973862959578 0.5974467212249372 0.38314235863256796 0.17106598068276965 0.1874615933755214 9.026806206536822 0.043937718683591656 0.07684464945120195 2.1128994672761107e-06 5.675121166386361 -0.3282506650710205 ET(ph)QSPEQVKSEK ddPTM_PC-9_Lapatinib_30min_R1 1 ETQSPEQVKSEK 12 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 ET(0.603)QS(0.397)PEQVKSEK 66.387 0.028385000000000004 54044000.0 252670.0 110990.0 126870.0 137470.0 102020.0 106850.0 77427.0 78763.0 120910.0 90152.0 True False 249066.8794659974 110733.0094742052 116439.23833236254 147580.00238647684 96019.38417903725 102280.27457951554 81435.79120677947 82422.61651846785 107291.84256125474 105734.65308001064 2.3555842120891586 1.0472726419257483 1.1012400848778652 1.395758136878752 0.9081165103589858 0.9673297410085496 0.7701901773409713 0.7795232132279065 1.0147273333375932 1.0 16.69008875213558 -2.977060645528387 1.3929237460157933 0.9677192782424392 199.99999999999997 0.8400790971508982 0.176064423367157 82.54929063035193 1.4650506731819388 0.05459195602955241 51343.673709539326 0.0010542396705140698 2.977060645528387 199.03228072175753 up ET(ph)S(ph)GSSKNS(ph)SST(ph)SK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETSGSSKNSSSTSK 14 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 4 ET(0.84)S(0.614)GS(0.273)S(0.273)KNS(0.943)S(0.106)S(0.207)T(0.65)S(0.094)K 65.467 0.042537 0.0 615.04 562.21 0.0 1077.4 890.74 1064.3 628.1 0.0 0.0 705.09 True False 719.1541244062831 618.0224932835504 0.0 1017.0367709779292 716.2058912305918 1008.4862344069297 568.6018209497939 0.0 0.0 832.9172355106309 0.8634160679426884 0.7419974841854047 0.0 1.2210538185758892 0.859876420724458 1.210788048813354 0.6826630506705809 0.0 0.0 1.0 9.702029336205184 -7.616854547183216 6.4620600677621605 0.25548518259326974 0.8079442829140643 0.21001868967005233 0.4101132287867603 0.29498651697548867 16.964528757552696 0.19702044351853587 0.11243023504481514 2.4162699500050674e-08 7.616854547183216 0.5524591003207946 ET(ph)SPESSLIQDEIAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ETSPESSLIQDEIAVK 16 0 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 ET(0.891)S(0.109)PESSLIQDEIAVK;ET(0.507)S(0.409)PES(0.071)S(0.012)LIQDEIAVK 182.15 3.7827999999999996e-06 25210000.0 32794.6 39334.0 40892.2 40557.7 51681.0 41069.9 41333.6 35200.0 34677.5 39212.5 True False 38346.078057125174 43238.81957065008 41867.22513253211 38285.38355883751 41554.4790451627 38916.12214457312 37418.182178650546 34276.03729748288 35184.59283411539 46321.41584402079 0.8278261222897166 0.9334520282421674 0.9038416544414924 0.8265158320668953 0.8970900022808044 0.8401323974123828 0.807794440149448 0.739960915981096 0.7595750732791353 1.0 15.499391730457125 -7.013284042119103 3.2597193063405014 0.8057720559273082 0.8793847695465015 0.07094962147004025 0.07318884974204477 0.43815691511046656 9.635522867856407 0.027827711749846083 0.022424885946319827 9.698754310221196e-08 7.013284042119103 0.0736127136191933 ET(ph)SSLESFVR ddPTM_PC-9_Lapatinib_30min_R1 1 ETSSLESFVR 10 0 A0A087X2H1;Q9ULT8;H0YJP0 A0A087X2H1 HECTD1 E3 ubiquitin-protein ligase HECTD1 1 ET(0.558)S(0.075)S(0.293)LES(0.075)FVR 154.84 0.00060593 930030.0 10681.0 7930.5 15807.0 7765.9 10921.0 9732.9 10372.0 10096.0 9891.3 7010.9 True False 10528.686981344492 7912.137414498469 14507.409476784536 8337.030192282968 10278.648251512102 9316.646555498051 10909.011409414226 10565.097017260048 8777.237633993376 8222.72472356296 1.2804377302299308 0.9622281762425446 1.7643068404335907 1.0139011668957438 1.2500294728410046 1.1330364166029248 1.3266905771700552 1.2848657072253444 1.0674366379846585 1.0 13.005400816502283 -8.387552072995994 4.021420729062345 1.004364431961266 1.2496455971318068 0.15462786137832352 0.20625131719518044 0.41120817826680167 10.607250917664906 0.18761182121806763 0.04949049671891066 4.096829848526345e-09 8.387552072995994 0.24528116517054088 ET(ph)VNSPAIYK ddPTM_PC-9_AZD4547_30min_R2 2 ETVNSPAIYK 10 0 Q9Y3A2 Q9Y3A2 UTP11L Probable U3 small nucleolar RNA-associated protein 11 1 ET(0.901)VNS(0.099)PAIYK;ET(0.915)VNS(0.085)PAIYK 156.36 9.059299999999999e-05 16657000.0 154846.0 176921.0 165788.0 222673.0 171504.0 164512.0 149380.0 167712.0 133513.0 172575.0 True False 204083.80700311647 234107.2533712783 163589.54279604516 171339.1801135556 147693.62997452944 154225.03863345346 162674.53061259497 141795.96403836217 140570.22460780822 166533.2017777415 1.225484196691845 1.405769245244696 0.9823238912704928 1.0288589799782284 0.8868719774669576 0.9260918362650905 0.9768294182544068 0.8514576224121715 0.8440972917545657 1.0 17.345450310981732 -5.349774481150665 4.824182895278666 0.9302268548260623 1.3143614652878555 0.8216689381539167 0.07068476416310146 0.07861984192815273 3.083545780543229 0.019012982983152755 0.04164141619663138 4.469156046062074e-06 5.349774481150665 0.3841346104617932 ET(ph)VNSPAIYK ddPTM_PC-9_Lapatinib_30min_R1 1 ETVNSPAIYK 10 0 Q9Y3A2 Q9Y3A2 UTP11L Probable U3 small nucleolar RNA-associated protein 11 1 ET(0.844)VNS(0.155)PAIYK 144.28 0.00032421 15155000.0 109860.0 144610.0 99189.0 102080.0 101690.0 85450.0 107070.0 95604.0 83804.0 69396.0 True False 108293.37625414334 144275.16442981217 91034.06330061263 109587.30372889727 95708.79413023226 81795.50269367895 112613.56070246658 100046.11085956106 74365.11102475715 81391.00613564234 1.3305324678462238 1.7726180235365332 1.118478166357836 1.3464301392989826 1.1759136380588364 1.0049697942959754 1.3836118515943916 1.2292035153470031 0.9136772544723655 1.0 16.312581762242637 -1.5228787452803716 0.19848052524106113 0.9876324324670699 3.616093810480727 0.38486596596697287 0.1856989822119435 54.604186203012155 0.6565563024184589 0.34297798988486095 44.52929431104636 0.02999999999999765 1.5228787452803716 2.6284613780136574 ET(ph)VSPPCFDEYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETVSPPCFDEYK 12 0 Q13029-5;Q13029-3;Q13029-2;Q13029 Q13029-5 PRDM2 PR domain zinc finger protein 2 1 ET(0.623)VS(0.377)PPCFDEYK 150.14 1.2974e-07 0.0 12971.0 17036.0 13718.0 15817.0 25032.0 15179.0 19849.0 17246.0 14638.0 9726.5 True False 15166.734111072277 18727.221492998287 14045.0891458047 14930.824769405874 20127.159293715536 14382.986518897671 17968.759025684532 16793.31077364744 14852.053057624722 11489.83745506837 1.3200129392937552 1.6298943798145187 1.2223923271959922 1.2994809393773994 1.751735772801302 1.2518006956271677 1.5638827873720873 1.461579490512254 1.2926251668663267 1.0 13.488070768096964 -8.61847069440706 2.8731966119352346 1.0004434419019563 1.4399712162858025 0.40059271300454935 0.16322696564252395 0.3880873243436961 7.33818439035485 0.15076290130867057 0.04027595416331486 2.4072949545145878e-09 8.61847069440706 0.43952777438384616 ETAPTSAYSS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 2 ETAPTSAYSSPAR 13 0 A0A6I8PRZ9;A0A6I8PIX2;A0A6I8PIU5;A0A6I8PIW1;O43301 A0A6I8PRZ9 HSPA12A Heat shock 70 kDa protein 12A 1 ETAPT(0.002)S(0.002)AYS(0.165)S(0.831)PAR;ETAPT(0.001)S(0.001)AYS(0.026)S(0.973)PAR 132.31 5.7685e-05 9215300.0 32638.0 25790.0 36051.0 41721.0 40897.0 33604.0 28107.0 42834.0 31272.0 34044.0 True False 43016.20508742691 34126.11314906234 35572.94018469504 32102.868033024475 35219.157483605835 31502.73656777964 30608.46854952613 36214.989527399404 32924.974076946666 32852.12992218713 1.3093886207473975 1.0387793190241466 1.0828199044918052 0.9771928976618155 1.0720509619018674 0.9589252399280158 0.9317042341554325 1.1023635183830538 1.0022173343077625 1.0 15.00369928825728 ETAPTSAYSS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 2 ETAPTSAYSSPAR 13 0 A0A6I8PRZ9;A0A6I8PIX2;A0A6I8PIU5;A0A6I8PIW1;O43301 A0A6I8PRZ9 HSPA12A Heat shock 70 kDa protein 12A 1 ETAPTS(0.002)AYS(0.285)S(0.712)PAR;ETAPTSAYS(0.064)S(0.935)PAR 99.161 0.0025765999999999996 8756100.0 41669.0 39212.0 46197.0 36617.0 38727.0 35958.0 33939.0 31525.0 34222.0 28178.0 True False 41074.792418841294 39121.2070231781 42398.86098557695 39309.93633073116 36449.15400021146 34420.160162192005 35696.19535519761 32989.76658767066 30367.557986363936 33048.5297551751 1.2428629268268538 1.1837503003307455 1.2829272981179343 1.1894609721503746 1.102897898037472 1.0415035227641896 1.080114474672142 0.9982219128070217 0.9188777295488811 1.0 15.01229847088609 -6.672111254284451 0.822152523462319 0.9743860471354384 1.2442852795000012 0.8676877129942757 0.04078425186398662 0.22089138215577542 0.3290967089579614 0.0270727665850473 0.028329632838027367 2.1275939451975422e-07 6.672111254284451 0.2698992323645628 ETAVPGPLGIEDIS(ph)PNLSPDDKSFSR ddPTM_PC-9_Lapatinib_30min_R1 1 ETAVPGPLGIEDISPNLSPDDKSFSR 26 1 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 ETAVPGPLGIEDIS(0.801)PNLS(0.197)PDDKS(0.002)FSR 130.19 3.0709e-12 8532400.0 123600.0 83593.0 92406.0 85877.0 83525.0 84840.0 73804.0 77199.0 87226.0 70077.0 True False 121837.44133453576 83399.44554443879 84808.7353774754 92192.6810572738 78612.22371646826 81211.59097169951 77625.20999425459 80785.94736880546 77401.68934949978 82189.7160782671 1.4823927754965498 1.0147187449220496 1.0318655353026682 1.1217057979550769 0.9564727494813088 0.9880991789089995 0.9444637808498346 0.9829203849770588 0.9417442113535492 1.0 16.326670268699075 -4.760750666620533 5.927317117198731 0.9979238220473134 1.5012788445310639 0.8960362886545462 0.04953199228865614 0.04328947245554767 5.6853675864271755 0.01335968423758557 0.08868316141628936 1.734799680049564e-05 4.760750666620533 0.5033550224837504 ETAVPGPLGIEDISPNLS(ph)PDDKSFSR ddPTM_PC-9_AZD4547_30min_R2 3 ETAVPGPLGIEDISPNLSPDDKSFSR 26 1 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 ETAVPGPLGIEDIS(0.345)PNLS(0.651)PDDKS(0.004)FSR;ETAVPGPLGIEDIS(0.006)PNLS(0.986)PDDKS(0.007)FSR;ETAVPGPLGIEDIS(0.043)PNLS(0.95)PDDKS(0.004)FS(0.004)R 111.93 1.0026e-10 21333400.0 93999.0 71577.0 97453.0 138705.0 143504.0 112844.0 99467.0 104280.0 97538.0 122352.0 True False 123888.72669933942 94712.86548547627 96160.709545341 106728.70522088784 123580.94665934858 105787.84684128457 108319.37030688861 88165.92211601087 102693.65955222651 118068.49372105049 1.0492953945193868 0.8021857694673873 0.8144485164054944 0.903955846790473 1.0466886022220445 0.8959870961953638 0.9174282392625823 0.7467353850072175 0.8697803818421816 1.0 16.849264511005124 -10.30344473390554 5.216473598054829 1.0000000358586671 0.8902042691638659 0.10469015400384063 0.09232966502961582 5.279423994491779e-08 1.2345234014293998e-08 0.09195136509410964 0.022301472168830556 4.972276443462353e-11 10.30344473390554 -0.10979576669480129 ETAVPGPLGIEDISPNLS(ph)PDDKSFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 13 ETAVPGPLGIEDISPNLSPDDKSFSR 26 1 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 ETAVPGPLGIEDIS(0.088)PNLS(0.881)PDDKS(0.018)FS(0.014)R;ETAVPGPLGIEDIS(0.067)PNLS(0.778)PDDKS(0.079)FS(0.075)R;ETAVPGPLGIEDIS(0.006)PNLS(0.986)PDDKS(0.004)FS(0.004)R;ETAVPGPLGIEDIS(0.037)PNLS(0.955)PDDKS(0.003)FS(0.005)R;ETAVPGPLGIEDIS(0.422)PNLS(0.525)PDDKS(0.028)FS(0.024)R;ETAVPGPLGIEDIS(0.315)PNLS(0.611)PDDKS(0.061)FS(0.012)R;ETAVPGPLGIEDIS(0.032)PNLS(0.909)PDDKS(0.029)FS(0.029)R;ETAVPGPLGIEDIS(0.056)PNLS(0.932)PDDKS(0.009)FS(0.003)R;ETAVPGPLGIEDIS(0.006)PNLS(0.971)PDDKS(0.022)FS(0.001)R;ETAVPGPLGIEDIS(0.011)PNLS(0.477)PDDKS(0.256)FS(0.256)R;ETAVPGPLGIEDIS(0.089)PNLS(0.89)PDDKS(0.015)FS(0.007)R;ETAVPGPLGIEDIS(0.029)PNLS(0.892)PDDKS(0.044)FS(0.036)R;ETAVPGPLGIEDIS(0.011)PNLS(0.971)PDDKS(0.009)FS(0.009)R 90.435 2.4779e-07 43932900.0 169081.1 124596.0 150280.7 218835.9 221934.9 242977.10000000003 230546.7 251872.4 205831.90000000002 183247.0 True False 197703.19072605198 136965.06745372273 153863.96183072825 206575.23399856058 178448.34951801004 230234.95313926175 208707.6475624352 245261.01638086757 208841.80214180282 216468.2305175465 0.9133127307105073 0.632725953024412 0.7107923479711556 0.9542981596175425 0.8243627671892729 1.063596965655426 0.9641490904390136 1.1330116007992552 0.9647688330176215 1.0 17.723795780968665 -6.320895152433356 1.158013758733675 1.0328517151749568 0.7476473519216478 0.5469190839090867 0.09820466234541618 0.3342894067914984 0.9297282486701761 0.04081837098067196 0.056768153911204135 4.776445729041939e-07 6.320895152433356 -0.285204363253309 ETAVPGPLGIEDISPNLS(ph)PDDKSFSR ddPTM_PC-9_Lapatinib_30min_R1 3 ETAVPGPLGIEDISPNLSPDDKSFSR 26 1 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 ETAVPGPLGIEDIS(0.019)PNLS(0.785)PDDKS(0.098)FS(0.098)R;ETAVPGPLGIEDIS(0.028)PNLS(0.958)PDDKS(0.005)FS(0.01)R;ETAVPGPLGIEDIS(0.299)PNLS(0.698)PDDKS(0.003)FSR 82.21600000000001 7.9452e-06 17205000.0 63044.9 43223.4 46136.2 48132.7 43336.3 45035.4 40472.6 37221.1 51958.0 41982.4 True False 62145.8681649813 43123.31887293779 42343.059726882144 51672.53932398027 40787.34403644396 43109.34092464497 42568.07319404729 38950.52818830602 46105.94289800413 49239.00190196831 1.2621268865016746 0.8757959586344489 0.8599495946563753 1.0494229640734185 0.8283544032360555 0.8755120790318394 0.8645194165145262 0.7910503195384427 0.9363703795174017 1.0 15.587513897552267 -4.760015142215943 24.984768622669776 0.8909916710810585 1.2621273420248333 0.6835149003742922 0.07422206425694414 20.051112294111565 351622.1349677597 0.018084415724804348 0.11031905158527189 1.7377402392236526e-05 4.760015142215943 0.37113567094377486 ETCSTLAES(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 ETCSTLAESPR 11 0 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 ET(0.001)CS(0.011)T(0.011)LAES(0.977)PR;ETCSTLAES(1)PR 91.12299999999999 0.0083638 77204000.0 28064.0 19279.2 33045.0 48196.0 37249.0 35319.0 29208.0 44723.0 34842.0 29483.0 True False 36987.768232537186 25510.824374695727 32606.801708780582 37085.15682077723 32077.619314542237 33110.49734666731 31807.45541660654 37812.08798230108 36683.67698864722 28450.809143926785 1.300060326770451 0.8966642827499816 1.146076427697697 1.303483378387274 1.1274765210461384 1.1637805160186525 1.117980696285268 1.3290338348908641 1.289372010584024 1.0 14.796182063059536 -5.518874486692462 24.94857052657496 1.1992773981863092 1.079114318546692 0.06718321092703616 0.13063454452833695 307.93595199410976 1918594.3598282605 0.03379890205053146 0.06039379027539451 3.0277883478532652e-06 5.518874486692462 -0.12016307963961714 ETCSTLAES(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ETCSTLAESPR 11 0 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 ETCSTLAES(1)PR;ET(0.002)CS(0.006)T(0.006)LAES(0.987)PR 150.51 0.00033797 27982600.0 66561.8 42387.8 59594.0 75590.0 71064.0 58735.0 77076.0 69275.0 62076.0 55967.5 True False 77829.39808452468 46595.780652789006 61014.94697150359 71354.93736608635 57139.519337192476 55654.83320294183 69774.80329808343 67456.60465292964 62983.744063745835 66113.96471151378 1.1772005872606617 0.7047797066188398 0.9228753295576874 1.0792717949595276 0.8642579459047568 0.841801477884286 1.0553716389955374 1.020307962883098 0.9526541682770567 1.0 16.01266741213226 -7.277527914730269 24.86093038638012 1.008775768263539 0.924624780990011 0.08057412610451142 0.12332065164866564 1965.1285739406344 3036617.70319543 0.05047368796080076 0.03415527839608998 5.278032805855461e-08 7.277527914730269 -0.08415098727352799 ETCSTLAES(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 ETCSTLAESPR 11 0 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 ETCSTLAES(1)PR;ETCST(0.002)LAES(0.998)PR 174.42 0.0026428000000000003 75971000.0 55715.0 52148.0 66495.0 56946.0 58054.0 52960.0 48020.0 55463.0 54921.0 46905.0 True False 54920.49388312032 52027.25450996358 61028.03777812283 61133.998806287156 54639.377858555425 50695.02425578977 50506.24063633546 58040.01345763606 48735.218636230886 55012.46675301613 0.9983281449583286 0.945735713752758 1.1093492326405612 1.1112753601970666 0.9932181027959404 0.9215188346923263 0.9180871830941191 1.0550338292993184 0.8858940802460729 1.0 15.747470974271552 -6.517820698313133 23.971759881706475 0.9571921927936026 1.0408527384621291 0.28770119415053297 0.06308518853344493 180.38823583115467 854928.5962518585 0.02129793572365379 0.021911250061035205 3.035144007194974e-07 6.517820698313133 0.08366054566852654 ETDPS(ph)PEER ddPTM_PC-9_AZD4547_30min_R2 1 ETDPSPEER 9 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H0Y482 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 ET(0.141)DPS(0.859)PEER 85.963 0.012029999999999999 4802500.0 75582.0 56704.0 55320.0 50455.0 49486.0 52959.0 43390.0 50300.0 78799.0 89966.0 True False 99615.50379673723 75032.45909284339 54586.42065455412 38823.3792719793 42615.723090537635 49647.46535808362 47251.625942432096 42527.29077901178 82964.1542686532 86816.31772351929 1.1474283453714202 0.864266776803371 0.6287576124616742 0.4471898865328368 0.4908722715728897 0.5718679006427577 0.5442712520117773 0.48985365763204647 0.9556285781765829 1.0 16.405678612153167 -4.954125623650834 2.2138616039851757 0.60375006971348 1.1912594696080683 0.41740509115765156 0.18352242053070875 0.37673754792514713 2.8447930733830225 0.047494814154829486 0.38266234424118467 1.111410195217154e-05 4.954125623650834 0.5875093998945883 ETDPS(ph)PEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETDPSPEER 9 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H0Y482 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 ET(0.02)DPS(0.98)PEER 83.081 0.014837000000000001 5472300.0 24367.0 29529.0 27014.0 29993.0 47999.0 34697.0 24712.0 30525.0 35960.0 37515.0 True False 28491.851829812524 32460.44396963764 27658.116211165518 28312.589448617964 38593.94051370453 32877.42823942236 22371.10046061343 29723.751093910952 36485.84697036376 44316.17253142339 0.6429222155773883 0.7324739957319378 0.6241088666119327 0.638877137427477 0.8708771157152306 0.7418832981596024 0.5048066920659877 0.6707201772182525 0.823307720099082 1.0 15.435545664628286 -8.539617852406222 2.9652836070070974 0.9988117881435468 0.6803955958882194 0.5600410172691861 0.08964898545272997 0.19710813385310783 4.398218283903871 0.09140986698727999 0.02440605754086064 2.8865703581726065e-09 8.539617852406222 -0.31841619225532736 ETDPS(ph)PEER ddPTM_PC-9_Lapatinib_30min_R1 2 ETDPSPEER 9 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H0Y482 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 ET(0.017)DPS(0.983)PEER;ET(0.012)DPS(0.988)PEER 77.744 0.022612 9460900.0 175343.0 228960.0 144876.0 193324.0 218750.0 147316.0 281940.0 260250.0 199482.0 192980.0 True False 172842.57666603202 228429.85718725997 132964.85451753248 207541.69186995827 205883.5550790473 141015.63809036877 296537.47365698474 272342.16508933494 177014.23652141436 226336.33587031387 0.763653683803856 1.0092496032901481 0.5874657907059105 0.91696143737555 0.9096354515388745 0.6230357911739274 1.3101629153654528 1.2032631174403279 0.7820849261377101 1.0 17.78810868684463 -7.257581846223953 24.986784564738482 1.0908163291696868 0.8115144395024113 0.36066435598563995 0.17668576753486587 365.68723920086813 2368712.216945394 0.06825499002228098 0.05083680359359677 5.526092545535017e-08 7.257581846223953 -0.27930188966727554 ETDPVKS(ph)PPLPEHQK ddPTM_PC-9_AZD4547_30min_R2 2 ETDPVKSPPLPEHQK 15 1 Q96JM3;A0A2R8Y4S6;S4R3K0;A0A2R8Y735 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 ET(0.032)DPVKS(0.968)PPLPEHQK;ET(0.001)DPVKS(0.999)PPLPEHQK 83.087 0.0030049 64127000.0 343629.0 387330.0 321181.0 386190.0 337730.0 411890.0 351997.0 397530.0 429440.0 434050.0 True False 452895.8740727811 512526.84784902417 316921.93008406245 297159.8620760218 290842.01914414734 386134.4531872018 383324.05109145585 336100.87283062673 452139.32168086426 418854.04161453777 1.0812737351823654 1.2236406884684938 0.7566404966809865 0.7094592209987353 0.694375582537181 0.9218830781691559 0.9151733372653489 0.8024295803260579 1.0794674916780633 1.0 18.676088068900903 -5.259403508805446 24.996290985916854 0.845771682103002 1.1524572288445702 0.47348467504947733 0.12266564923509694 143.67480815554066 1763998.8278482456 0.032494225549354404 0.07765580285552814 5.502961712849208e-06 5.259403508805446 0.3066855467415682 ETDPVKS(ph)PPLPEHQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ETDPVKSPPLPEHQK 15 1 Q96JM3;A0A2R8Y4S6;S4R3K0;A0A2R8Y735 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 ET(0.01)DPVKS(0.99)PPLPEHQK;ET(0.395)DPVKS(0.605)PPLPEHQK;ET(0.017)DPVKS(0.983)PPLPEHQK;ET(0.392)DPVKS(0.608)PPLPEHQK;ET(0.002)DPVKS(0.998)PPLPEHQK 76.76100000000001 0.005737699999999999 91696100.0 419146.0 436614.0 419602.0 460340.0 468932.0 389495.0 483851.0 385775.0 380116.0 338504.0 True False 490099.1392891462 479958.1524385971 429606.9030294463 434548.6422424172 377048.1408565275 369069.19653323945 438017.1305021151 375648.8150123999 385674.477391178 399872.0956038107 1.2256397600064886 1.2002791835570714 1.0743607962459492 1.08671909598054 0.9429218617697771 0.9229681205334956 1.0953930902347788 0.9394224281771065 0.9644946012269395 1.0 18.609179083070174 -5.476351289998 1.1569642553573447 0.9791597651087334 1.246093584661239 0.7575681159736805 0.05089542543256048 0.31871146859407173 0.7194322246561113 0.01765174776447325 0.07724220588577432 3.3392482727436296e-06 5.476351289998 0.2669338195525057 ETDPVKS(ph)PPLPEHQK ddPTM_PC-9_Lapatinib_30min_R1 2 ETDPVKSPPLPEHQK 15 1 Q96JM3;A0A2R8Y4S6;S4R3K0;A0A2R8Y735 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 ET(0.007)DPVKS(0.993)PPLPEHQK;ET(0.322)DPVKS(0.678)PPLPEHQK 62.203 0.018548 83481000.0 78818.0 121120.0 129558.0 118580.0 131316.0 154127.0 137174.0 128339.0 151306.0 121782.0 True False 77694.04086654886 120839.55408159034 118906.24134834274 127300.76877128411 123592.25105718926 147535.34749758532 144276.19852246318 134302.098464554 134264.32495718496 142831.85643568513 0.5439545687171912 0.8460266294725535 0.8324910444742717 0.8912631393865946 0.8652989195924989 1.0329302662534396 1.0101121845141627 0.9402811236653502 0.9400166623027967 1.0 17.12395826049967 -4.210145969985617 0.6842936604238408 0.9691237203763251 7.47658047332098e-19 0.8312768607199639 0.05473825677814128 2.569339266133437 0.5205672276088205 0.02372848765108598 2.310054373000456 6.163877939797565e-05 4.210145969985617 -0.9691237203763251 ETDSPS(ph)TPGKDQR ddPTM_PC-9_AZD4547_30min_R2 1 ETDSPSTPGKDQR 13 1 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 ET(0.001)DS(0.12)PS(0.44)T(0.44)PGKDQR 69.878 0.013918 16763000.0 46229.0 48461.0 54117.0 62875.0 59246.0 60724.0 56961.0 54470.0 55898.0 58932.0 True False 60928.86037706538 64125.070543494025 53399.37322058037 48380.14015906646 51020.715560400786 56926.91868056926 62030.41865192152 46052.91309607896 58852.65416197128 56868.80861750479 1.0713932972795015 1.1275965173597058 0.9389922968096699 0.8507324372569073 0.8971651912661328 1.0010218266300481 1.090763463485464 0.809809704399248 1.034884598300796 1.0 15.795349960178232 -5.266086447512214 24.629189213904656 0.9471286088537958 1.0994949127105038 0.3396026968050585 0.08143868779939589 314.01271867362834 1664260.034558129 0.02143038717445609 0.04711596183767728 5.418930143691541e-06 5.266086447512214 0.15236630385670802 ETDSPS(ph)TPGKDQR ddPTM_PC-9_Lapatinib_30min_R1 2 ETDSPSTPGKDQR 13 1 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 ET(0.003)DS(0.09)PS(0.453)T(0.453)PGKDQR;ETDS(0.303)PS(0.394)T(0.303)PGKDQR 73.435 0.010045 54036000.0 74703.0 77791.0 76864.0 80474.0 87258.0 79798.0 79629.0 73086.0 74543.0 64999.0 True False 73637.72152114764 77610.87971896482 70544.53862362033 86392.32641339453 82125.6559958285 76385.22555822348 83751.79999231055 76481.84237356078 66147.18236741061 76233.9905442766 0.9659434196663095 1.0180613551102053 0.9253685674849745 1.1332520545834208 1.0772839701750891 1.0019838265433454 1.0986149274668708 1.0032511984157542 0.867686210509896 1.0 16.218146776949478 -8.015417785688113 23.80111656197883 0.9343849222050163 1.0328335813509046 0.25983162294092965 0.0650645048250071 486.9383211690791 751701.613655016 0.04133563341090767 0.016754857483393254 9.65121997366384e-09 8.015417785688113 0.0984486591458883 ETDVS(ph)PFPPR ddPTM_PC-9_Lapatinib_30min_R1 3 ETDVSPFPPR 10 0 Q9H8V3-2;Q9H8V3-4;Q9H8V3;Q9H8V3-3 Q9H8V3-2 ECT2 Protein ECT2 1 ET(0.19)DVS(0.81)PFPPR;ET(0.016)DVS(0.984)PFPPR;ET(0.027)DVS(0.973)PFPPR 103.08 0.0029671999999999997 8999500.0 53743.0 48389.7 46876.0 41305.0 44793.0 44009.0 38217.3 37683.0 45326.0 27501.9 True False 52976.614964740824 48277.6566227043 43022.036226592776 44342.707489440756 42158.36380642633 42126.837659989695 40196.00479531496 39433.88974855492 40220.908576060196 32255.56677102175 1.6424022352735332 1.4967232467319942 1.3337863982363372 1.3747303776809787 1.3070104799491915 1.3060330937305449 1.246172639924804 1.2225452440036533 1.2469447169099033 1.0 14.977260546593424 -1.5228787452803376 0.1418786647001342 0.9802172932429083 3.106956871390368 0.9001717646303988 0.0510787352395089 23.118120706366234 0.21864067946045038 0.2231982371792107 9.993567356158085 0.029999999999999995 1.5228787452803376 2.12673957814746 ETDYPAGEDLSES(ph)GQVDK ddPTM_PC-9_Lapatinib_30min_R1 1 ETDYPAGEDLSESGQVDK 18 0 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9;H0YBS5 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 ETDYPAGEDLS(0.001)ES(0.999)GQVDK 179.1 7.1812e-33 0.0 8001.2 6291.8 7694.3 9315.1 6693.8 6356.8 6890.0 7334.3 7265.3 7702.6 True False 7887.101420759627 6277.231723667038 7061.704354856914 10000.163528262661 6300.083844517146 6084.934482424558 7246.73048697108 7675.078353178523 6447.005406999297 9033.984146930645 0.8730479589605348 0.6948464400172507 0.7816821725612806 1.1069494218296012 0.6973760128478463 0.6735604561019686 0.802163294633764 0.8495784615458043 0.7136392207628247 1.0 13.141146666761115 -10.720009267633756 3.2814226242666478 1.0004616245769626 0.7995496048923525 0.19756229192426844 0.12140085501831167 43399385.964840285 63977817.89976034 207455.94544596178 0.03224225228156646 1.905420056788884e-11 10.720009267633756 -0.20091201968461014 ETEAAPT(ph)SPPIVPLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETEAAPTSPPIVPLK 15 0 A0A1W2PRB5;A0A0J9YVS1;A0A3B3IT55;A0A0G2JNB1;A0A0G2JNT7;Q7Z3B3;Q7Z3B3-4;Q7Z3B3-2 A0A1W2PRB5 KANSL1 KAT8 regulatory NSL complex subunit 1 1 ETEAAPT(0.5)S(0.5)PPIVPLK 163.99 0.00077822 10323000.0 53968.0 55062.0 58742.0 66057.0 81755.0 59373.0 72810.0 69243.0 56902.0 55175.0 True False 63103.71648341287 60528.19146791924 60142.632060275595 62356.040449683525 65735.69463317796 56259.37535980707 65912.9097012491 67425.44461902282 57734.084101992186 65177.79073494034 0.968178205671896 0.9286628280186774 0.922747325156489 0.9567068743288327 1.0085597239787776 0.8631678785891662 1.011278672658579 1.034484965794914 0.885793817970609 1.0 15.992092830893137 ETEAAPTS(ph)PPIVPLK ddPTM_PC-9_AZD4547_30min_R2 4 ETEAAPTSPPIVPLK 15 0 A0A1W2PRB5;A0A0J9YVS1;A0A3B3IT55;A0A0G2JNB1;A0A0G2JNT7;Q7Z3B3;Q7Z3B3-4;Q7Z3B3-2 A0A1W2PRB5 KANSL1 KAT8 regulatory NSL complex subunit 1 1 ETEAAPT(0.098)S(0.902)PPIVPLK;ETEAAPT(0.037)S(0.963)PPIVPLK;ETEAAPT(0.235)S(0.765)PPIVPLK;ETEAAPT(0.356)S(0.644)PPIVPLK 115.83 0.00015390000000000003 36421600.0 227618.0 206821.0 291383.0 380722.0 319622.0 298919.0 245812.0 323104.0 242666.0 264330.0 True False 299995.78925148415 273671.84364490956 287519.0710337297 292952.42499626434 275248.0023773154 280227.54767599446 267688.791799058 273175.70099128893 255492.8293475422 255075.8871557904 1.1761040708181814 1.0729036236881202 1.1271903206520038 1.1484912520066644 1.0790827994227643 1.0986046184163318 1.0494476556914378 1.070958545071898 1.0016345809727485 1.0 17.960566998916292 -7.560615522212743 0.5839823216229179 0.9956661734397055 1.1308686494431226 0.7177000553761057 0.029124821755223112 0.4348800199512467 0.306601193762895 0.02670364569580348 0.01708696512083168 2.7503279212102153e-08 7.560615522212743 0.13520247600341706 ETEAAPTS(ph)PPIVPLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ETEAAPTSPPIVPLK 15 0 A0A1W2PRB5;A0A0J9YVS1;A0A3B3IT55;A0A0G2JNB1;A0A0G2JNT7;Q7Z3B3;Q7Z3B3-4;Q7Z3B3-2 A0A1W2PRB5 KANSL1 KAT8 regulatory NSL complex subunit 1 1 ETEAAPT(0.04)S(0.96)PPIVPLK;ETEAAPT(0.024)S(0.976)PPIVPLK;ET(0.001)EAAPT(0.168)S(0.831)PPIVPLK 180.85 1.7607999999999998e-05 20400500.0 103136.0 106609.0 120056.0 137154.0 156506.0 138184.0 147810.0 133212.0 130485.0 103578.0 True False 120594.88777114704 117192.43696566402 122918.5903549155 129469.7060392678 125839.7727877214 130937.38778097072 133808.3667482712 129715.32614978083 132393.09627163303 122355.87147700286 0.9856076894014293 0.9577998632267571 1.0045990345303406 1.058140524654773 1.0284735114765078 1.0701357131486802 1.0935998831361424 1.0601479486349064 1.0820330456844214 1.0 16.90072380795472 -5.629048721311711 2.4620163778948863 1.0606289630808137 0.9711665508623755 0.6339066450058853 0.026116298658830982 0.1667856487567052 2.0348205621923845 0.007423662719686521 0.015378713107877175 2.349369242155115e-06 5.629048721311711 -0.0894624122184382 ETEAAPTS(ph)PPIVPLK ddPTM_PC-9_Lapatinib_30min_R1 4 ETEAAPTSPPIVPLK 15 0 A0A1W2PRB5;A0A0J9YVS1;A0A3B3IT55;A0A0G2JNB1;A0A0G2JNT7;Q7Z3B3;Q7Z3B3-4;Q7Z3B3-2 A0A1W2PRB5 KANSL1 KAT8 regulatory NSL complex subunit 1 1 ETEAAPT(0.04)S(0.96)PPIVPLK;ETEAAPT(0.022)S(0.978)PPIVPLK;ETEAAPT(0.004)S(0.996)PPIVPLK;ETEAAPT(0.212)S(0.788)PPIVPLK 233.62 8.450100000000001e-32 31265600.0 270401.0 231596.0 260948.0 221954.0 255393.0 261252.0 253472.0 230363.0 270310.0 207866.0 True False 266545.03215452953 231059.75369121603 239493.8627284101 238277.23757683922 240371.28586195703 250078.8609681572 266595.5399119791 241066.5059614774 239864.84130950936 243795.36113596472 1.093314618098403 0.9477610755782755 0.9823561105202668 0.9773657565369013 0.9859551254049577 1.0257736644492106 1.0935217908567945 0.9888067797444045 0.9838777907498276 1.0 17.895311149493338 -6.76541841896995 24.432222431574598 1.0223917955380684 0.9926522764489508 0.042391915011472436 0.045515113944027984 206.57877034515448 1268437.5289523609 0.01586219145231064 0.014502795943606326 1.7162540734739653e-07 6.76541841896995 -0.02973951908911754 ETEEILADVLK ddPTM_PC-9_Lapatinib_30min_R1 2 ETEEILADVLK 11 0 P56537 P56537 EIF6 Eukaryotic translation initiation factor 6 0 ; 143.89 0.00074868 1527180.0 14496.8 11369.0 14638.8 12047.7 10605.2 10908.1 14205.7 10689.3 13766.3 13380.5 False True 14290.072973612472 11342.675779009272 13435.254371402116 12933.728047949046 9981.422986625423 10441.585991023054 14941.201636976064 11185.963901208177 12215.794328434395 15693.301596604464 0.9105842314726427 0.722771795927472 0.8561139470045667 0.8241559603205164 0.6360307883705675 0.6653530442110591 0.9520750968176683 0.7127858871729367 0.7784081796450982 1.0 13.937861281630246 -9.535761254923646 12.324793907175522 0.9999999936608567 0.7807095006159124 0.3031840117555884 0.09799069927800166 0.0 0.0 0.09452207917797237 0.022924971553163285 2.912317668969004e-10 9.535761254923646 -0.2192904930449443 ETEEQDSDS(ph)AEQGDPAGEGKEVLCDFCLDDTRR ddPTM_PC-9_Lapatinib_30min_R1 1 ETEEQDSDSAEQGDPAGEGKEVLCDFCLDDTRR 33 2 H0Y626;O95361 H0Y626 TRIM16 Tripartite motif-containing protein 16 1 ET(0.001)EEQDS(0.466)DS(0.533)AEQGDPAGEGKEVLCDFCLDDTRR 53.498999999999995 0.00073924 4049800.0 10092.0 7863.7 12842.0 7681.0 10095.0 8956.2 8631.6 8214.7 8815.7 7786.4 True False 9948.086229353858 7845.492085794289 11786.180331553549 8245.886363064867 9501.231947533632 8573.164203921917 9078.502013256839 8596.384951236732 7822.783032563506 9132.268865274169 1.0893334806623869 0.8590956093755735 1.2906081178107873 0.9029395087589013 1.0404021265364252 0.9387770257752407 0.9941124322103808 0.9413197397116551 0.8566089268691992 1.0 13.156757619573767 -6.665046140264729 1.1121682082115896 0.9369487352347814 1.045452928269276 0.13542195726469897 0.11402213507528164 1.0212791339181804 2.692735501234869 0.05591661675122864 0.05556873492281434 2.162488764637945e-07 6.665046140264729 0.10850419303449454 ETEGFRR ddPTM_PC-9_AZD4547_30min_R2 1 ETEGFRR 7 1 Q5JXB8;Q5JXB7;Q02809;Q02809-2 Q5JXB8 PLOD1 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 0 73.975 0.022083000000000002 2020400.0 2781.7 3401.3 6998.0 8116.4 6344.0 5531.5 4087.6 6335.7 4275.0 4396.5 False True 3666.222737045638 4500.703708953308 6905.20194758803 6245.289377129975 5463.245105411045 5185.614430564007 4451.388481269544 5356.663144902287 4500.967772414525 4242.579873190453 0.8641493729353432 1.060841243648465 1.627595037449528 1.4720499233485187 1.2877176785602016 1.2222785629406159 1.0492173663950528 1.2625957094530866 1.0609034848953267 1.0 12.050726105672464 -7.046857816883933 4.4167808070135 1.1155385327887952 1.2816614290650175 0.12594987425384907 0.20532709729954154 0.5314399705728948 22.43169447169029 0.08699925348774974 0.06885767450466863 8.977226506682132e-08 7.046857816883933 0.16612289627622223 ETEGFRR ddPTM_PC-9_Lapatinib_30min_R1 1 ETEGFRR 7 1 Q5JXB8;Q5JXB7;Q02809;Q02809-2 Q5JXB8 PLOD1 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 0 102.77 0.0081472 0.0 8925.8 5496.6 6110.3 5702.2 4469.9 5752.0 5911.0 5502.2 6813.9 3710.5 False True 8798.516455208752 5483.872960410097 5607.934720440093 6121.558809981576 4206.98927016152 5506.000368566896 6217.042657254872 5757.852298768645 6046.446828452024 4351.854981069532 2.0217853061469406 1.2601230933164862 1.288630881505583 1.406655055513158 0.9667117329189105 1.2652076855772698 1.428596008897094 1.323080002393271 1.3893952934447327 1.0 12.087414766439283 -4.7609476257298065 24.99999831952291 1.2707524730583168 2.0217861484940665 0.697781662470969 0.15046907952917074 6.683862964027256 339460.00896361005 0.03700145081525967 0.2122188725496206 1.7340131005599953e-05 4.7609476257298065 0.7510336754357496 ETEPLVS(ph)PHQDK ddPTM_PC-9_AZD4547_30min_R2 1 ETEPLVSPHQDK 12 0 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 ETEPLVS(1)PHQDK 73.80199999999999 0.012352 4064900.0 21563.0 25435.0 20609.0 27187.0 22524.0 23978.0 24312.0 28786.0 20504.0 22496.0 True False 28419.585461737468 33656.366341465706 20335.711194318606 20919.457184962877 19396.93139254071 22478.65186948637 26475.720901415305 24337.785136473824 21587.799580254374 21708.42188724948 1.3091502279320366 1.550382912045481 0.9367659841852835 0.9636562848103665 0.8935210257698912 1.0354806989765244 1.2196059685465168 1.121121805301228 0.994443524839272 1.0 14.4059672313343 -5.264147598918542 24.99998203892114 1.0259704110173857 1.4297665834588882 0.714819684273071 0.10333796098556033 122.77549239546067 1133370.8805831017 0.02916465681316634 0.06548379984750691 5.443176301200504e-06 5.264147598918542 0.40379617244150245 ETEPLVS(ph)PHQDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ETEPLVSPHQDK 12 0 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 ETEPLVS(1)PHQDK;ETEPLVS(1)PHQDK;ETEPLVS(1)PHQDK 97.579 0.0022255 17133800.0 79269.0 101909.0 103706.0 94916.0 105583.0 98011.0 116844.0 86638.0 100776.0 84106.0 True False 92687.67606588433 112025.85202688217 106178.74434719502 89598.16424182375 84894.76908390735 92871.13062149537 105775.69044269677 84363.84430054903 102249.65835053902 99353.75201727031 0.932905644567633 1.1275452587579091 1.0686938559576327 0.9018095685631401 0.8544696839345371 0.9347521229530608 1.0646371002104698 0.8491259020181177 1.0291474279981427 1.0 16.600286830310743 -5.754085000708522 24.995281632560545 0.9418670911546325 1.05149797830298 0.2252311008114939 0.08006701660703293 220.49083865459687 749372.4009174779 0.021522562378618822 0.036333891375418384 1.7616312238015734e-06 5.754085000708522 0.10963088714834757 ETERAS(ph)PIKMDLAPSK ddPTM_PC-9_AZD4547_30min_R2 1 ETERASPIKMDLAPSK 16 2 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 ET(0.032)ERAS(0.968)PIKMDLAPSK 65.25 0.025957 247430000.0 160340.0 109800.0 152970.0 236310.0 175880.0 186080.0 142190.0 172350.0 137110.0 180380.0 True False 211324.78472081738 145290.7027439724 150941.51785117763 181832.38045310526 151462.09790978755 174444.38818391945 154844.6345414705 145717.26770899966 144357.3546843874 174064.95110339904 1.2140570711175798 0.8346924629167074 0.8671562936384275 1.0446237413130468 0.8701470166720421 1.0021798591739184 0.8895796285231989 0.8371430709358593 0.8293303951732099 1.0 17.409266212407303 -7.407696872316914 6.028832935115295 0.8728094698999742 0.9595338878918424 0.10581454816299862 0.11194736936065855 0.5290677297302768 24.356457138692477 0.04612518490790071 0.030706228959481354 3.9111378908503975e-08 7.407696872316914 0.08672441799186814 ETERAS(ph)PIKMDLAPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETERASPIKMDLAPSK 16 2 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 ET(0.022)ERAS(0.978)PIKMDLAPSK 87.669 0.011803 7568800.0 44059.0 32359.0 40595.0 58857.0 58422.0 54491.0 56098.0 58405.0 56037.0 42675.0 True False 51517.3184950839 35571.3876668192 41562.93875739485 55559.433106968565 46974.628485836074 51633.39603407686 50783.99132565122 56871.9306352127 56856.43511341144 50411.63968488588 1.0219330062880203 0.7056185414552982 0.8244710748786853 1.1021151752702476 0.9318210790100472 1.0242356002865203 1.0073862235605278 1.128150780072002 1.1278434002307964 1.0 15.62146925964126 -5.75354545854681 24.989126244424824 1.044010438069139 0.8361685752482465 0.48174509335056803 0.09242730291054616 142.83179830010675 452145.66586133355 0.025147004804650763 0.0425664172579419 1.7638211318243312e-06 5.75354545854681 -0.20784186282089256 ETERAS(ph)PIKMDLAPSK ddPTM_PC-9_Lapatinib_30min_R1 3 ETERASPIKMDLAPSK 16 2 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 ET(0.045)ERAS(0.955)PIKMDLAPSK;ET(0.018)ERAS(0.982)PIKMDLAPSK;ET(0.029)ERAS(0.971)PIKMDLAPSK 82.609 0.011470000000000001 515001500.0 301255.0 279391.0 313748.0 274397.0 286380.0 290376.0 255258.0 234502.0 279875.0 220461.0 True False 296959.0484565993 278744.08730523125 287952.8505423036 294577.070741559 269535.691444743 277957.2953795173 268474.0102530137 245397.8190116396 248352.53028559426 258567.3901041825 1.1484783457687682 1.0780326443830335 1.1136472020941273 1.1392661333777139 1.0424195074875495 1.074989755156372 1.0383134939979848 0.9490671616121562 0.9604944002626454 1.0 17.980180811837386 -7.235831325727528 1.0558806313185807 0.9636021009109473 1.1125618001583064 0.7856697766359846 0.030646482312361216 0.23210632254715577 0.5060324316976136 0.021488831863860202 0.012478035415256473 5.8099002260113836e-08 7.235831325727528 0.14895969924735908 ETESAPGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 ETESAPGSPR 10 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YBW1 Q6PKG0 LARP1 La-related protein 1 1 ETES(0.387)APGS(0.612)PR;ETESAPGS(1)PR;ET(0.001)ES(0.011)APGS(0.988)PR 93.839 0.0065373 620140000.0 46643.0 42262.0 60854.0 88800.0 68266.0 53758.0 46534.0 63627.0 46589.0 56724.0 True False 61474.50376533039 55922.365021546095 60047.03619870275 68328.53194632371 58788.44425693411 50396.50376177528 50675.43585169705 53794.90915300559 49051.599426671426 54738.11002544186 1.1230658810974201 1.0216349266635951 1.0969877507789974 1.2482808031655663 1.0739947767580884 0.920684030529212 0.9257797872112042 0.9827688447409331 0.8961142320016641 1.0 15.740258002341571 -6.661798625066366 4.831859223107774 0.9431197508330921 1.1184642729099203 0.6723916514579571 0.059111588545466484 0.13373898420928607 5.2099764134446325 0.020842077162083774 0.0206683065733219 2.1787197733219478e-07 6.661798625066366 0.17534452207682827 ETESAPGS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ETESAPGSPR 10 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YBW1 Q6PKG0 LARP1 La-related protein 1 1 ETESAPGS(1)PR;ETESAPGS(1)PR;ETESAPGS(1)PR 130.1 0.00022437 452130000.0 66596.0 68134.0 91852.0 94171.0 95207.0 93831.0 102739.0 93703.0 88886.0 77023.0 True False 77869.38746904409 74897.89323808097 94042.10003064966 88894.90417650127 76551.87179916803 88910.3371799648 93006.81815405306 91243.39553653506 90185.7895942088 90986.66018626757 0.8558330123298311 0.82317444210778 1.0335811847377077 0.9770103001309854 0.841352695466031 0.9771799184402182 1.0222027928451252 1.0028216812194435 0.991197933956261 1.0 16.47336742273054 -2.654306753328219 0.38913693703180546 0.99768633282739 9.579006266227277e-10 0.4042073110925961 0.05845494111025774 31.37072496354022 0.976189067767782 0.047332829968277715 20.574769868690613 0.002216630203986929 2.654306753328219 -0.9976863318694894 ETESAPGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 ETESAPGSPR 10 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YBW1 Q6PKG0 LARP1 La-related protein 1 1 ETES(0.001)APGS(0.999)PR;ETES(0.001)APGS(0.999)PR 77.288 0.021972 435070000.0 37989.0 27875.0 37637.0 30184.0 35958.0 38944.0 33637.0 37491.0 43748.0 41589.0 True False 37447.26989367064 27810.457150134895 34542.63114302141 32403.832050872265 33843.02113614799 37278.455902898015 35378.559272894956 39232.968727624444 38820.639553136825 48777.60323614089 0.7677144305836814 0.5701480865203569 0.7081658148678299 0.6643178405876087 0.6938229615815279 0.7642535391176665 0.72530335493569 0.8043234215033239 0.7958701735548451 1.0 15.57393125034684 -8.901587643479552 0.34731873531880847 1.0407881111515502 0.6536295027805833 0.7748489751093788 0.05050088809098992 1.0336444736134152 0.2724858971578041 0.12586893834075277 0.047700082338403775 1.2543315799612085e-09 8.901587643479552 -0.38715860837096694 ETFASDT(ph)NEALASLDESQEGHAEAK ddPTM_PC-9_Lapatinib_30min_R1 1 ETFASDTNEALASLDESQEGHAEAK 25 0 Q9H814 Q9H814 PHAX Phosphorylated adapter RNA export protein 1 ET(0.015)FAS(0.202)DT(0.783)NEALASLDESQEGHAEAK 89.20100000000001 1.4584000000000001e-05 734210.0 2492.5 3022.2 4327.3 2184.5 3850.8 3666.0 3071.4 3478.3 4650.3 2436.3 True False 2456.9564929314793 3015.202281583415 3971.5260978610568 2345.155417278376 3624.303514964089 3509.2137258633966 3230.4220635243787 3639.9145161584415 4126.534244170069 2857.411208834308 0.8598540123784998 1.0552216888704227 1.3899035902085848 0.8207273108007058 1.2683870993991928 1.228109456214737 1.1305415382766144 1.2738504366836856 1.4441513462997522 1.0 11.480492953507907 -4.927453520740199 3.9920133037801726 1.194389288986853 0.8698168378230922 0.2654472539064836 0.17224900695548215 0.29817082350658125 8.884620512482204 0.042512594175991084 0.21338261420329363 1.1818067856354453e-05 4.927453520740199 -0.3245724511637609 ETFASDTNEALASLDES(ph)QEGHAEAK ddPTM_PC-9_AZD4547_30min_R2 1 ETFASDTNEALASLDESQEGHAEAK 25 0 Q9H814 Q9H814 PHAX Phosphorylated adapter RNA export protein 1 ETFASDTNEALAS(0.004)LDES(0.996)QEGHAEAK 79.917 0.00049881 0.0 6507.6 5917.6 7780.5 6536.6 8380.6 6841.7 6965.8 9721.9 8295.8 8018.6 True False 8576.88143351123 7830.348475024874 7677.325486311609 5029.687859463283 7217.098349685972 6413.887417443694 7585.742705457332 8219.603742037269 8734.299051788637 7737.871254671891 1.1084290693429113 1.0119512482579944 0.9921753972937032 0.6500092459442912 0.9326981688056011 0.8288955975548423 0.980339741486044 1.0622564619532178 1.1287728581055332 1.0 12.917721009593178 -7.623751506159581 3.593505603794977 1.0720617598539055 0.9155227793313658 0.22388920514451072 0.11814061436197501 0.360521753165627 8.995765338207358 0.06549135656234477 0.03521638584480422 2.3782006520004302e-08 7.623751506159581 -0.15653898052253967 ETFASDTNEALASLDES(ph)QEGHAEAK ddPTM_PC-9_Lapatinib_30min_R1 3 ETFASDTNEALASLDESQEGHAEAK 25 0 Q9H814 Q9H814 PHAX Phosphorylated adapter RNA export protein 1 ETFASDTNEALAS(0.007)LDES(0.993)QEGHAEAK;ETFASDTNEALAS(0.002)LDES(0.998)QEGHAEAK;ETFASDTNEALAS(0.001)LDES(0.999)QEGHAEAK 125.62 5.9096e-09 0.0 15216.7 18505.5 19097.4 18840.6 23765.3 21330.699999999997 21287.1 18694.300000000003 18185.399999999998 19403.9 True False 14999.707067598974 18462.65165172452 17527.28549009585 20226.200574399154 22367.47177837751 20418.435685290326 22389.24187941975 19562.905424897446 16137.1687512484 22757.83826092846 0.6591006973342918 0.8112656149517469 0.7701647796744989 0.8887575499261844 0.9828469436299164 0.8972045345952514 0.983803541563017 0.8596117610381212 0.7090817926654008 1.0 14.474075903874274 -5.006002000014432 1.0363687574235343 0.9025604926386515 0.6162728898234504 0.4323854923918047 0.08445720462475488 1.3645323415011412 1.5326038400518227 0.029090755410304942 0.39847406601272733 9.862749436240125e-06 5.006002000014432 -0.28628760281520105 ETFLTSPEELYR ddPTM_PC-9_AZD4547_30min_R2 4 ETFLTSPEELYR 12 0 O95433;G3V438;O95433-2;H0YJ63;H0YJG7 O95433 AHSA1 Activator of 90 kDa heat shock protein ATPase homolog 1 0 ;;; 172.56 0.00035664 17564300.0 28446.499999999996 26333.3 36448.8 50532.0 40515.0 35144.3 37372.2 46594.0 34016.2 38668.1 False True 37491.89527604296 34845.02424925177 35965.46509677717 38882.62811161744 34890.19158980588 32946.72136528443 40698.25340045542 39393.96792360389 35814.22688655132 37314.34158865362 1.0047583229350971 0.9338239069947115 0.9638509904115095 1.0420290552156146 0.9350343622414374 0.8829506287015051 1.0906866279219238 1.055732628432137 0.9597979050886309 1.0 15.187442609551805 -7.271478776871633 24.98955433376803 1.031198669404433 0.961912730837601 0.28404192350261015 0.05120227916232626 951.6155532364775 2368704.237686459 0.02185373299837321 0.014915144576472587 5.3520630762565824e-08 7.271478776871633 -0.06928593856683207 ETFLTSPEELYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ETFLTSPEELYR 12 0 O95433;G3V438;O95433-2;H0YJ63;H0YJG7 O95433 AHSA1 Activator of 90 kDa heat shock protein ATPase homolog 1 0 ;; 182.28 0.0028041 10122100.0 29708.4 30523.8 29123.5 33740.7 33286.0 30787.8 37277.0 30936.0 36391.0 28038.5 False True 34737.44535235369 33554.00113923348 29817.914691488808 31850.317967825315 26763.8472455503 29173.233569175678 33745.852697891176 30123.962779401445 36923.1495299919 33121.65809735613 1.0487834048116853 1.0130531823197542 0.9002542869032564 0.9616160481521214 0.8080467217819228 0.8807902516059235 1.018845511861161 0.9094944066766402 1.1147735847481384 1.0 15.015487276690916 -10.102245639106034 8.475771428851067 1.0000705069512914 0.9546786060556625 0.011599733413426239 0.0860367643382031 0.0 0.0 0.08487560333397205 0.020585357504940786 7.902315427076084e-11 10.102245639106034 -0.045391900895628945 ETFLTSPEELYR ddPTM_PC-9_Lapatinib_30min_R1 4 ETFLTSPEELYR 12 0 O95433;G3V438;O95433-2;H0YJ63;H0YJG7 O95433 AHSA1 Activator of 90 kDa heat shock protein ATPase homolog 1 0 ;;; 181.87 0.00073901 24561600.0 56805.8 52362.0 61815.0 55977.0 59584.0 60367.0 57827.0 44362.9 71991.0 54548.3 False True 55995.73887509209 52240.75900611171 56732.80931280039 60093.73531379792 56079.3862666512 57785.24413235016 60820.99911031597 46424.162288728796 63882.615481162 63976.900973959055 0.8752493169039933 0.8165565729320902 0.8867702006368318 0.9393036298875789 0.8765567792894121 0.9032204319473192 0.9506712295281753 0.7256394352021698 0.9985262572684565 1.0 15.965263489886985 -14.522878745184839 0.25302301701609115 1.7284624568140574 0.8727698411591115 0.20916210804577906 0.07027990787850642 300.92866714582567 2.971018670845914 113.42575618733133 0.09540516258223897 3.0000000006596828e-15 14.522878745184839 -0.8556926156549459 ETHPDSLR ddPTM_PC-9_AZD4547_30min_R2 1 ETHPDSLR 8 0 P56597 P56597 NME5 Nucleoside diphosphate kinase homolog 5 0 95.815 0.0052967 9118400.0 15756.0 18865.0 18958.0 33586.0 24651.0 21276.0 16217.0 25869.0 20332.0 22791.0 False True 20766.080254840937 24962.74232481818 18706.60453306285 25843.26659852734 21228.63415723322 19945.60835662658 17660.281583508207 21871.540460482225 21406.708011399318 21993.09402704051 0.9442091335265989 1.135026399383665 0.850567205781191 1.175062797747013 0.9652409129489744 0.9069032457235645 0.8029921375225736 0.9944731029472781 0.9733377206990416 1.0 14.424762958888751 -6.513854592496451 24.663259856307338 0.9279293178513554 1.0275308682093256 0.15397789267112183 0.09965700431650969 625.3526677712182 1709112.2535022292 0.030911794296122494 0.03253892821066854 3.062988790955313e-07 6.513854592496451 0.09960155035797025 ETHPDSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ETHPDSLR 8 0 P56597 P56597 NME5 Nucleoside diphosphate kinase homolog 5 0 ; 93.195 0.008402799999999998 8478700.0 57723.5 65024.0 69951.0 65291.0 87465.0 82398.0 75018.0 74192.0 78547.0 56255.0 False True 67494.94845890682 71479.15299135481 71618.89713064482 61632.956946278035 70326.86112275619 78076.90382661106 67911.7519567132 72244.53861292201 79695.6012786753 66453.586185665 1.0156705203287653 1.0756252159461923 1.0777280992864469 0.9274587043968013 1.0582854163245552 1.1749088094128075 1.0219426197252053 1.0871428128961715 1.1992671254191365 1.0 16.020059436577913 -6.527572901887105 24.99744845208374 1.0995591023908342 1.026784063090407 0.1997814654400144 0.06832243880904483 216.17641231784813 1151177.1756234718 0.02222129114277465 0.022303292269826906 2.9677485270754187e-07 6.527572901887105 -0.07277503930042717 ETHPDSLR ddPTM_PC-9_Lapatinib_30min_R1 1 ETHPDSLR 8 0 P56597 P56597 NME5 Nucleoside diphosphate kinase homolog 5 0 76.47800000000001 0.020899 7709400.0 46147.0 45705.0 60818.0 46294.0 64261.0 58821.0 58935.0 52503.0 56932.0 49345.0 False True 45488.93531767665 45599.17288060686 55817.77880426911 49698.615192256846 60481.294321986956 56305.36294844813 61986.36592883033 54942.481051624825 50519.71863946206 57874.21750192049 0.7859965504702877 0.7879013289310339 0.9644671014760047 0.8587349831659954 1.0450472927773053 0.9728919954136693 1.0710532013115062 0.9493429617394243 0.8729227075560135 1.0 15.820633161853545 -5.262430864853543 1.1425946681870407 0.980876776023184 0.742620404791512 0.5543833244356002 0.06357200720152503 0.6159676442018803 1.1391084579297746 0.021147975663673053 0.14454656466089832 5.4647353583847165e-06 5.262430864853543 -0.23825637123167198 ETHQQVVSR ddPTM_PC-9_AZD4547_30min_R2 1 ETHQQVVSR 9 0 J3QRP6;O14745 J3QRP6 SLC9A3R1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 0 114.89 0.0016884 1009800.0 5307.6 6385.7 6819.1 5919.7 6742.8 7763.5 8137.8 7517.8 6097.8 7457.2 False True 6995.3063950618025 8449.752645830453 6728.674278479215 4555.004623453292 5806.67860920012 7278.0471177228 8862.048434992488 6356.096751857951 6420.1172590945735 7196.1256977950225 0.9720934137108315 1.1742085951082757 0.9350412376122001 0.6329801360819752 0.8069173403932278 1.0113841007464446 1.2315027289903961 0.8832664990559481 0.892163023369891 1.0 12.813004671640826 -6.8222121143746515 24.543153919150367 1.0106079199295208 0.905886095399337 0.0922406134828504 0.15513077010707013 172.69342384518956 69740.27448579448 0.06142507475435647 0.054171849616835605 1.5058714017927532e-07 6.8222121143746515 -0.10472182453018386 ETHQQVVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ETHQQVVSR 9 0 J3QRP6;O14745 J3QRP6 SLC9A3R1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 0 ;;; 110.39 0.0019348 2040120.0 9460.5 15398.019999999999 16712.02 14189.769999999999 17399.280000000002 13247.01 17495.309999999998 11926.37 10262.91 13166.66 False True 11061.975796607767 16926.633663630982 17110.49793748879 13394.76319075504 13990.015985776557 12552.313475571684 15838.027581724455 11613.315424533552 10412.985643231817 15553.671230776794 0.7112131684202573 1.0882725635949821 1.100093841744027 0.8611962405538174 0.8994671276125371 0.807032197693225 1.018282265757617 0.7466607241609767 0.6694873183783867 1.0 13.924967528478145 -5.952812170696092 24.004027251217057 0.8525193683253881 0.9790256278607743 0.1105395131034409 0.14018692961780568 159.95069140993397 81363.72468556953 0.03965973435736658 0.058824874397003395 1.1147765623570428e-06 5.952812170696092 0.1265062595353862 ETHQQVVSR ddPTM_PC-9_Lapatinib_30min_R1 2 ETHQQVVSR 9 0 J3QRP6;O14745 J3QRP6 SLC9A3R1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 0 ; 121.6 0.0013484999999999999 1696920.0 10881.9 14565.8 12221.6 9634.64 16065.0 13646.0 14993.4 13445.4 12988.3 13449.6 False True 10726.722110503944 14532.07378502008 11216.787224740288 10343.203565816857 15120.088285005222 13062.392390379677 15769.684888730371 14070.122368845894 11525.420881137592 15774.345439534498 0.6800106002256086 0.921247340545683 0.7110778236558827 0.6556977977605444 0.9585239744471715 0.8280782515160355 0.9997045487039705 0.8919623589313956 0.7306433680761151 1.0 13.945292521002605 -6.270206403634847 24.956505960163305 0.8973241328850705 0.7526018448765742 0.371794143410921 0.10109459254641923 761.3807505816545 2167368.7204101575 0.03111143628945216 0.03582192967638229 5.367766262418946e-07 6.270206403634847 -0.1447222880084963 ETHVMDYR ddPTM_PC-9_AZD4547_30min_R2 3 ETHVMDYR 8 0 H0YM70;A0A087X1Z3;Q9UL46 H0YM70 PSME2 Proteasome activator complex subunit 2 0 ;; 76.064 0.017293 21448900.0 91905.0 83299.0 119442.0 172704.0 141451.0 124807.0 97058.0 139309.0 93681.0 109499.0 False True 121128.87825724501 110223.77274927267 117858.12103798347 132889.7610502015 121812.97027198884 117002.79856013763 105695.97397374004 117781.99505235288 98632.78640644798 105665.47333890143 1.1463430241659707 1.0431389674066134 1.1153891362410926 1.2576460110483152 1.1528171542022763 1.1072945103352154 1.0002886528009085 1.1146686929096514 0.9334438515228387 1.0 16.689144521167684 -7.113713237776977 3.670049980765087 1.0216536883797631 1.1417754773601294 0.47789344370064724 0.06444571949251149 0.2513741322693182 6.1016684439500715 0.02705113077207692 0.020695139429315043 7.696384605275641e-08 7.113713237776977 0.1201217889803663 ETHVMDYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ETHVMDYR 8 0 H0YM70;A0A087X1Z3;Q9UL46 H0YM70 PSME2 Proteasome activator complex subunit 2 0 ;; 75.043 0.018272 23728300.0 138698.0 137943.0 161409.0 162891.0 167827.0 162401.0 161954.0 142300.0 134953.0 131104.0 False True 162176.83198963068 151637.06940647276 165257.60270704125 153764.74536974708 134942.5041061998 153884.40566937887 146612.5446745789 138564.7757793128 136926.43231900694 154872.11738130695 1.047166105376728 0.9791114886944481 1.067058457657452 0.9928497651463405 0.8713156789479483 0.9936224045449301 0.9466684329859562 0.8947044705158629 0.8841257847717264 1.0 17.240717904319098 -6.0122223984247904 21.837446053105772 0.9304759240989798 1.0265856993658993 0.5007016760033549 0.045084961278171985 90.20581469666585 161171.52747428502 0.012826877630941785 0.01751967460440574 9.72249215912507e-07 6.0122223984247904 0.09610977526691944 ETHVMDYR ddPTM_PC-9_Lapatinib_30min_R1 4 ETHVMDYR 8 0 H0YM70;A0A087X1Z3;Q9UL46 H0YM70 PSME2 Proteasome activator complex subunit 2 0 ;;; 82.75 0.010875 18075400.0 121930.0 110093.0 119403.0 101363.0 109768.0 115594.0 100648.0 105596.0 124381.0 89697.0 False True 120191.2558407767 109838.0864225936 109586.14624890868 108817.57315705562 103311.66205219126 110650.31408277492 105859.06096555378 110502.37565715068 110371.90199000432 105201.00693626024 1.1424914964321478 1.0440782804402517 1.0416834347916968 1.0343776768504376 0.9820406197707432 1.051799001789178 1.006255206565582 1.050392756450539 1.0491525243373103 1.0 16.68278898795483 -4.1439995619511425 1.4225054283923053 1.026550679034941 1.5474005855606126 0.698751703206655 0.02261950502422278 3.554329882757183 1.786963596510419 0.006302658121824541 4.128730604788587 7.177950152711841e-05 4.1439995619511425 0.5208499065256715 ETIELS(ph)PTGRPK ddPTM_PC-9_AZD4547_30min_R2 2 ETIELSPTGRPK 12 1 A0A0B4J1V9;Q9NRZ9-6;Q9NRZ9-5;Q9NRZ9-3;Q9NRZ9-2;Q9NRZ9;A0A087WSW7;F6XU50;Q9NRZ9-4 A0A0B4J1V9 HELLS Lymphoid-specific helicase 1 ET(0.004)IELS(0.952)PT(0.045)GRPK;ET(0.002)IELS(0.981)PT(0.017)GRPK 61.657 0.025908999999999998 15788500.0 70509.0 64106.0 76056.0 67649.0 75902.0 84688.0 83493.0 100864.0 80486.0 83577.0 True False 92929.39532169208 84827.0108388441 75047.44774589245 52053.56821663128 65364.317463888496 79392.44597226864 90923.71525262704 85277.78642414001 84740.32564457427 80650.99466885898 1.1522411558995198 1.0517788551416039 0.9305210438386549 0.6454175603209298 0.8104589129032405 0.9843951249236571 1.127372521888246 1.0573680681097355 1.0507040364784772 1.0 16.299404705800562 -7.000782188596271 24.955600293780442 1.0625335522767578 0.909691192873504 0.20679124156011996 0.1293916635977665 47.97120828535982 1530570.134340355 0.051895060850936495 0.04522679679918464 9.982005651260435e-08 7.000782188596271 -0.15284235940325386 ETIELS(ph)PTGRPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETIELSPTGRPK 12 1 A0A0B4J1V9;Q9NRZ9-6;Q9NRZ9-5;Q9NRZ9-3;Q9NRZ9-2;Q9NRZ9;A0A087WSW7;F6XU50;Q9NRZ9-4 A0A0B4J1V9 HELLS Lymphoid-specific helicase 1 ET(0.001)IELS(0.964)PT(0.035)GRPK 55.18600000000001 0.038574000000000004 7228400.0 39288.0 40349.0 37873.0 37734.0 31738.0 30715.0 43881.0 28622.0 23220.0 29221.0 True False 45938.682426629195 44354.58206274877 38776.035954152336 35619.88631527858 25519.16673313933 29104.25132933275 39724.27400907163 27870.70282751576 23559.54857207584 34518.53598669128 1.3308409848071479 1.2849496884760643 1.1233395289157846 1.0319060556047897 0.7392887908971087 0.843148485224112 1.1508099307684267 0.8074126561526651 0.6825187656034802 1.0 15.075083657231735 -5.640601343979951 1.6363502715101272 0.8746365905595394 1.3201702705128484 0.6472683246430548 0.12739104139424093 0.2565681675733105 1.3638617185094628 0.04171564364435444 0.10576643856513454 2.2876978078222665e-06 5.640601343979951 0.44553367995330906 ETIELS(ph)PTGRPK ddPTM_PC-9_Lapatinib_30min_R1 1 ETIELSPTGRPK 12 1 A0A0B4J1V9;Q9NRZ9-6;Q9NRZ9-5;Q9NRZ9-3;Q9NRZ9-2;Q9NRZ9;A0A087WSW7;F6XU50;Q9NRZ9-4 A0A0B4J1V9 HELLS Lymphoid-specific helicase 1 ETIELS(0.986)PT(0.014)GRPK 65.956 0.019062 10295000.0 37781.0 43851.0 43690.0 42311.0 42697.0 42730.0 39615.0 42086.0 40578.0 38617.0 True False 37242.23601181316 43749.46570369744 40097.976848277096 45422.69208535838 40185.646405531785 40902.53750849506 41666.07086231632 44041.46920249667 36007.67833471672 45291.896996081974 0.8222714984765341 0.9659446524724287 0.8853234134076083 1.0028878253716713 0.8872590699614125 0.9030873118878942 0.9199453682834413 0.9723917990519702 0.7950136939027218 1.0 15.466965345732037 -4.7460733958532 24.827329632754953 0.9239516906822112 0.8222711973603221 0.21051380084621985 0.06003248124303108 1236.817053858875 1998246.2531284764 0.013799678294125931 0.32552129544292413 1.794430342123503e-05 4.7460733958532 -0.10168049332188911 ETIHLPAS(ph)SPHPPPFP ddPTM_PC-9_AZD4547_30min_R2 4 ETIHLPASSPHPPPFP 16 0 Q5SZC6;Q9Y2T3-3;Q5SZC3 Q5SZC6 GDA Guanine deaminase 1 ETIHLPAS(0.5)S(0.5)PHPPPFP;ETIHLPAS(0.5)S(0.5)PHPPPFP;ETIHLPAS(0.5)S(0.5)PHPPPFP;ETIHLPAS(0.5)S(0.5)PHPPPFP 127.05 1.4716e-05 39143400.0 75047.0 66130.9 120238.4 184978.6 133585.9 117996.9 94653.9 138080.4 101062.6 115819.2 True False 98910.3849254281 87506.42016476643 118643.96025362499 142334.64166088117 115039.80364548066 110618.53518969896 103077.91373109882 116743.2469519337 106404.56271261303 111764.40506062069 0.8849900366022563 0.7829542877922824 1.061554080561453 1.2735239057880663 1.029306276744223 0.9897474525069031 0.9222785525963266 1.0445476526145556 0.9520433867553763 1.0 16.77010126352043 -5.266245327909864 24.876863911825595 1.0385145676867142 0.8339721559553326 0.4266318400223821 0.0927020682312799 339.1000075715892 1755281.3007279362 0.026296533268796538 0.057749083110935046 5.416948068519305e-06 5.266245327909864 -0.20454241173138166 ETIHLPAS(ph)SPHPPPFP ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ETIHLPASSPHPPPFP 16 0 Q5SZC6;Q9Y2T3-3;Q5SZC3 Q5SZC6 GDA Guanine deaminase 1 ETIHLPAS(0.5)S(0.5)PHPPPFP;ETIHLPAS(0.5)S(0.5)PHPPPFP;ETIHLPAS(0.5)S(0.5)PHPPPFP;ETIHLPAS(0.5)S(0.5)PHPPPFP 139.34 2.1261000000000003e-06 31423100.0 53327.8 54021.5 73303.9 78704.1 87213.7 81192.7 74121.6 72884.3 69436.6 55763.0 True False 62355.143267939246 59384.3975043442 75051.74298258866 74294.564439135 70124.80155378375 76934.81188042049 67100.26545408722 70971.16435229934 70451.97891385862 65872.39048033493 0.9466051378013115 0.9015066414216801 1.1393505296425226 1.1278559028659265 1.0645552870093322 1.1679371481651035 1.0186402066905231 1.0774038081020691 1.0695221230037317 1.0 16.007386285397615 -5.255162717302289 24.99915265530639 1.0875781210676434 0.9240558729512952 0.6159171608350495 0.05015889638463075 300.30694703037875 1196076.289884795 0.01248067318509668 0.03136380065100227 5.556960153941965e-06 5.255162717302289 -0.1635222481163482 ETIHLPAS(ph)SPHPPPFP ddPTM_PC-9_Lapatinib_30min_R1 4 ETIHLPASSPHPPPFP 16 0 Q5SZC6;Q9Y2T3-3;Q5SZC3 Q5SZC6 GDA Guanine deaminase 1 ETIHLPAS(0.554)S(0.446)PHPPPFP;ETIHLPAS(0.5)S(0.5)PHPPPFP;ETIHLPAS(0.5)S(0.5)PHPPPFP;ETIHLPAS(0.5)S(0.5)PHPPPFP 109.14 0.00040602 32940600.0 113251.0 95049.0 136852.0 101571.0 115723.0 122390.0 102042.0 97750.0 126782.0 92716.0 True False 111636.01997230994 94828.91988029299 125600.55682399654 109040.87017092311 108916.40066017167 117155.66500502492 107325.23546465934 102291.82185391925 112502.47608635348 108741.83706369561 1.0266151739455998 0.8720555256460021 1.1550343475476317 1.0027499361359173 1.0016053029927552 1.0773743406266063 0.9869728005587538 0.940685063045254 1.0345831845792257 1.0 16.73054758050408 -9.778769890603604 9.336002186647404 0.999999757063119 1.0096913041701823 0.0018389895911788967 0.07137701451898501 0.0 0.0 0.06731215421990833 0.01632559539626751 1.664294237216514e-10 9.778769890603604 0.009691547107063214 ETIHLPASS(ph)PHPPPFP ddPTM_PC-9_AZD4547_30min_R2 1 ETIHLPASSPHPPPFP 16 0 Q5SZC6;Q9Y2T3-3;Q5SZC3 Q5SZC6 GDA Guanine deaminase 1 ETIHLPAS(0.426)S(0.574)PHPPPFP 101.04 0.00095987 3484800.0 7412.7 6195.0 9484.2 12294.0 11022.0 9837.9 7670.4 12765.0 7069.8 8460.2 True False 9769.784406261708 8197.412600172209 9358.433311133802 9459.808240406568 9491.785553568809 9222.734557795477 8353.050740466268 10792.462560518596 7443.495194717243 8164.010973084466 1.1966892791388006 1.004091325599373 1.1463033724461138 1.1587206670341519 1.1626375301137908 1.1296817934470527 1.0231552564058326 1.32195591065467 0.9117448787437135 1.0 12.995062406131678 -8.299219067866145 24.9989881767477 0.9558723292688232 1.1351432409766522 0.42930066060129657 0.08588569989036281 600.1423382598524 397111.8792862637 0.07767810153593195 0.02005826971340152 5.020892605640532e-09 8.299219067866145 0.17927091170782905 ETIHLPASS(ph)PHPPPFP ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETIHLPASSPHPPPFP 16 0 Q5SZC6;Q9Y2T3-3;Q5SZC3 Q5SZC6 GDA Guanine deaminase 1 ETIHLPAS(0.38)S(0.62)PHPPPFP 99.711 0.0010630999999999998 3698600.0 7853.1 8191.1 10400.0 12320.0 11694.0 11017.0 8625.2 11337.0 9013.9 8206.9 True False 9182.474724204896 9004.25827490598 10647.975442219631 11629.750341978912 9402.6446460814 10439.249125679931 7808.158614959656 11039.415762544422 9145.711234876579 9694.746004215345 0.9471599070478267 0.9287771202041667 1.0983243333646715 1.199593092683626 0.969870138113269 1.0767944947852033 0.8054010503797224 1.1387008754787804 0.9433678026118433 1.0 13.242987385855516 ETIHLPASS(ph)PHPPPFP ddPTM_PC-9_Lapatinib_30min_R1 1 ETIHLPASSPHPPPFP 16 0 Q5SZC6;Q9Y2T3-3;Q5SZC3 Q5SZC6 GDA Guanine deaminase 1 ETIHLPAS(0.101)S(0.899)PHPPPFP 142.83 2.7419e-05 4697100.0 6412.1 4197.7 4735.7 3400.4 5210.5 5640.3 5460.7 5403.7 5420.9 3616.5 True False 6320.662278164876 4187.980483555921 4346.349026330644 3650.4767594018704 4904.028634237142 5399.07751718148 5743.428326589694 5654.775629176717 4810.341157392327 4241.607206316659 1.4901573792009923 0.9873569804670086 1.0246938990149774 0.8606352690945853 1.1561722704860544 1.272884841656507 1.3540688817287234 1.3331681492702927 1.1340845399896295 1.0 12.050395311061676 -6.523578830229031 14.56921057347591 1.2443952188944924 1.0698384704385169 0.08914850567040833 0.179413844317046 0.26368807977916425 4861.275501501893 0.05839981407334855 0.05980798648120069 2.9951678802473105e-07 6.523578830229031 -0.17455674845597557 ETIQGTGSWGPEPPGPGIPPAYS(ph)SPRR ddPTM_PC-9_AZD4547_30min_R2 3 ETIQGTGSWGPEPPGPGIPPAYSSPRR 27 1 Q9H4L4 Q9H4L4 SENP3 Sentrin-specific protease 3 1 ETIQGTGSWGPEPPGPGIPPAY(0.308)S(0.346)S(0.346)PRR;ETIQGTGSWGPEPPGPGIPPAY(0.285)S(0.358)S(0.358)PRR;ETIQGTGSWGPEPPGPGIPPAY(0.31)S(0.345)S(0.345)PRR 100.71 6.2811e-06 5014500.0 8406.8 4353.73 9434.2 11060.3 10366.400000000001 8162.1 8188.6 12987.599999999999 6254.9 8857.7 True False 11079.987527697183 5760.988080669531 9309.096343803232 8510.518714931575 8927.20429708907 7651.7225967109325 8917.369536579854 10980.664845357724 6585.521244368564 8547.594619074052 1.296269654970776 0.6739893896949467 1.0890895928814734 0.9956624166452932 1.0444112870266349 0.89519016023947 1.0432606989433781 1.28464969792253 0.770453155285687 1.0 13.061302772570931 -7.484054065929878 24.603890305079428 1.0493219918938075 0.9885600405779443 0.0 0.18740689641769587 2227.468842696797 1411589.856230485 0.073778281049264 0.04973083742219502 3.280544506116988e-08 7.484054065929878 -0.06076195131586315 ETIQGTGSWGPEPPGPGIPPAYS(ph)SPRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETIQGTGSWGPEPPGPGIPPAYSSPRR 27 1 Q9H4L4 Q9H4L4 SENP3 Sentrin-specific protease 3 1 ETIQGTGSWGPEPPGPGIPPAY(0.298)S(0.351)S(0.351)PRR 65.125 0.00018511 2245600.0 8162.2 5614.4 9114.9 6700.0 12813.0 11921.0 10934.0 11671.0 9871.5 9481.5 True False 9543.899249201613 6171.760527723032 9332.233784450751 6324.620721693078 10302.38462889011 11295.841774278877 9898.252364695183 11364.648616446668 10015.852012456786 11200.420894487303 0.8521018396638106 0.5510293395099723 0.8332038476379001 0.5646770582350144 0.9198212036800157 1.0085194012520136 0.8837393217577181 1.0146626384406854 0.8942388957352893 1.0 13.451265327098417 -6.389995063058272 6.348676930941383 0.9569518025612664 0.6999683588884154 0.6107146789384301 0.0993874143404236 0.15034301209563888 7.127532556156175 0.028274764535271116 0.03205134924115064 4.0738490881879944e-07 6.389995063058272 -0.2569834436728511 ETIQGTGSWGPEPPGPGIPPAYS(ph)SPRR ddPTM_PC-9_Lapatinib_30min_R1 2 ETIQGTGSWGPEPPGPGIPPAYSSPRR 27 1 Q9H4L4 Q9H4L4 SENP3 Sentrin-specific protease 3 1 ETIQGTGSWGPEPPGPGIPPAY(0.291)S(0.355)S(0.355)PRR;ETIQGTGSWGPEPPGPGIPPAY(0.022)S(0.489)S(0.489)PRR 87.958 2.7667e-07 6895200.0 3739.2999999999997 7439.2 8479.9 6751.1 10084.0 13792.1 10897.2 8665.1 11443.2 4637.5 True False 3685.9768962963612 7421.974989463082 7782.7153553606095 7247.598415009401 9490.878945906794 13202.24403395541 11461.403695590903 9067.712179502776 10154.346313761893 5439.085695919673 0.6776831810282986 1.3645629806919473 1.4308866950191823 1.3325030750014566 1.7449401381976242 2.4272910507476566 2.1072298427268925 1.6671390535922699 1.8669215528962053 1.0 12.409148441133521 -4.700205442264342 0.7328918530406793 1.8500972182006152 5.77331770792652e-07 0.42444487672270215 0.37090349192347816 2.9968102267239374 1.1271155237799284 0.15604215595468213 4.7179762126333795 1.994318682741423e-05 4.700205442264342 -1.8500966408688444 ETLLNSATTSLNSK ddPTM_PC-9_Lapatinib_30min_R1 1 ETLLNSATTSLNSK 14 0 P50991;P50991-2 P50991 CCT4 T-complex protein 1 subunit delta 0 166.62 0.0019798 4546100.0 19384.0 20996.0 16879.0 19263.0 22486.0 22737.0 22488.0 19038.0 15200.0 21266.0 False True 19107.58060540975 20947.385051990383 15491.273774824205 20679.66527948425 21163.41768917692 21764.591512535753 23652.31860537092 19922.57498163596 13488.015936904088 24941.799764836185 0.7660866812164966 0.839850582134924 0.6210968703495223 0.8291168028956418 0.848512051604786 0.872615116701411 0.9483003964580287 0.7987625259394271 0.5407795774192671 1.0 14.606277951297681 -5.946813455089991 24.999920608727322 0.832919921819347 0.7475970700913864 0.10215786751376599 0.12426375773722084 251.80510938617303 118356.96781111506 0.03543402968016769 0.05255717841049121 1.1302813063976567e-06 5.946813455089991 -0.08532285172796061 ETLPAEQDLTTK ddPTM_PC-9_Lapatinib_30min_R1 1 ETLPAEQDLTTK 12 0 P25786;P25786-2;F5GX11 P25786 PSMA1 Proteasome subunit alpha type-1 0 106.67 0.007573699999999999 4126300.0 36022.0 49441.0 35941.0 27891.0 37894.0 41029.0 34773.0 38717.0 45785.0 36032.0 False True 35508.31967437424 49326.52240214598 32986.069716272075 29942.197181648506 35665.14942247044 39274.28531327038 36573.37579440429 40515.9331633575 40628.21116257588 42260.08319037794 0.8402330756049957 1.1672130927886335 0.7805490956483154 0.7085219649654155 0.8439441366407655 0.9293470894589393 0.8654354897893708 0.95872819229524 0.9613850256647479 1.0 15.367007986818223 -7.836000919732757 4.529331045415262 0.9742405050850881 0.8782015315357832 0.13403082051857196 0.11321547879238822 0.5149515405207242 19.654188005791422 0.06937911811517504 0.03234338059054631 1.4588111708558494e-08 7.836000919732757 -0.0960389735493049 ETLPISS(ph)TPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETLPISSTPSK 11 0 A0A0D9SFF0;Q08050-2;Q08050;Q08050-3 A0A0D9SFF0 FOXM1 Forkhead box protein M1 1 ETLPIS(0.001)S(0.533)T(0.379)PS(0.088)K 114.86 0.0014162 4169000.0 45642.0 57645.0 57348.0 57016.0 60467.0 51366.0 43052.0 42029.0 35132.0 38115.0 True False 53368.289129408724 63367.61463746697 58715.393813501156 53821.57836836604 48618.925415991405 48672.276535324956 38973.80289051189 40925.78328340649 35645.73903678588 45024.947781826035 1.1853048533895338 1.407388964547446 1.3040635626722739 1.1953723662082891 1.0798219167644665 1.0810068402782498 0.8656046216725066 0.9089579288735091 0.7916886258149977 1.0 15.458436982500672 -6.598425754239355 0.9904926060270011 0.8768973564475351 1.3140870040973 0.8196733670791292 0.0790458763433213 0.20022039261020036 0.4248907411197992 0.0411015644475285 0.04443815773148043 2.521008127245687e-07 6.598425754239355 0.437189647649765 ETLPISST(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 1 ETLPISSTPSK 11 0 A0A0D9SFF0;Q08050-2;Q08050;Q08050-3 A0A0D9SFF0 FOXM1 Forkhead box protein M1 1 ETLPISS(0.012)T(0.988)PSK 146.36 0.0005571 5087800.0 55380.0 57685.0 61446.0 60820.0 65769.0 83378.0 72429.0 69524.0 73989.0 69753.0 True False 72989.68802444098 76330.5481583428 60631.185891896814 46798.88865963297 56638.109605576676 78164.3604793575 78875.04068643501 58780.663302584835 77899.90748846273 67310.96870116067 1.0843654375038343 1.1339986577407049 0.9007623432234355 0.6952639304212835 0.8414395261050528 1.1612425431935536 1.1718007066071972 0.8732702030118199 1.1573137185755502 1.0 16.038553998818244 -6.760458706714861 24.999908925548517 1.0709970224847685 0.9276397055104407 0.20071510379875168 0.14113506747084661 50.17799740531673 1279174.791242213 0.053084922754946355 0.05021731173938918 1.7359663129633948e-07 6.760458706714861 -0.14335731697432774 ETMQSLNDR ddPTM_PC-9_AZD4547_30min_R2 3 ETMQSLNDR 9 0 P05783;F8VZY9;CON__Q92764;C4AM86;CON__Q497I4;Q92764 P05783 KRT18;KRT35 Keratin, type I cytoskeletal 18;Keratin, type I cuticular Ha5 0 ;; 152.06 0.00057462 33322600.0 78150.0 85604.0 117676.0 111501.0 91610.0 106561.0 89396.0 108483.0 84211.0 86748.0 False True 103000.07437901864 113273.81892254097 116115.5393518674 85796.16712327756 78891.53280370499 99897.72382451977 97352.07081700051 91719.44504134284 88662.2215398361 83710.97892403611 1.2304249180085027 1.3531536768352905 1.3871004836442893 1.024909375401447 0.9424275503371601 1.1933646590750346 1.1629546335295287 1.0956680500006342 1.0591468727213549 1.0 16.353129228137924 -5.762723760980529 24.999999999966256 1.0762428320726065 1.3265191170410549 0.6877968901137768 0.07866025052574695 20.429712277900972 397671.4011487008 0.023353007739774084 0.03690692798077922 1.7269359842727703e-06 5.762723760980529 0.25027628496844834 ETMQSLNDR ddPTM_PC-9_Lapatinib_30min_R1 6 ETMQSLNDR 9 0 P05783;F8VZY9;CON__Q92764;C4AM86;CON__Q497I4;Q92764 P05783 KRT18;KRT35 Keratin, type I cytoskeletal 18;Keratin, type I cuticular Ha5 0 ;;;;; 169.65 0.00077678 182348000.0 222702.0 294388.0 280829.0 266706.0 297626.0 291486.0 269753.0 266338.0 289109.0 244414.0 False True 219526.22864145503 293706.3626731453 257740.32365128872 286320.44894513447 280120.2238352294 279019.82326705346 283719.490428434 278713.03579467157 256546.49996726343 286660.6342388169 0.765805284790404 1.0245786396623213 0.8991130726256794 0.9988132821425385 0.9771841347489008 0.9733454473368747 0.989739980105072 0.9722752359588928 0.894948483765422 1.0 18.128984274069992 -4.751631986875503 24.99913727565443 0.9687645616388999 0.7658048773746958 0.7031294231869198 0.03979712745273621 211.98472032809897 540313.782602015 0.00931950539682855 0.12072398378431996 1.771609551660493e-05 4.751631986875503 -0.20295968426420408 ETNGNEDEEGR ddPTM_PC-9_AZD4547_30min_R2 1 ETNGNEDEEGR 11 0 Q9BUQ8;H0YIL9 Q9BUQ8 DDX23 Probable ATP-dependent RNA helicase DDX23 0 104.79 0.0087568 0.0 0.0 0.0 0.0 451.86 478.05 0.0 0.0 444.3 0.0 0.0 False True 0.0 0.0 0.0 347.6906581674081 411.68100924365524 0.0 0.0 375.64364399830885 0.0 0.0 0.0 ETNLDS(ph)LPLVDTHSK ddPTM_PC-9_Lapatinib_30min_R1 2 ETNLDSLPLVDTHSK 15 0 P08670 P08670 VIM Vimentin 1 ET(0.001)NLDS(0.999)LPLVDTHSK;ET(0.011)NLDS(0.989)LPLVDTHSK 169.6 7.416399999999999e-05 12470900.0 88072.0 101272.0 90179.0 68258.0 88247.0 70688.0 74809.0 78041.0 69648.0 66688.0 True False 86816.07712957312 101037.51090613336 82764.83072100657 73277.92102201282 83056.48496027727 67664.83902177626 78682.2439767517 81667.06976267729 61803.50881404585 78214.93194382565 1.109968070955107 1.2917931192307244 1.0581717411765912 0.9368789206981779 1.0619006230156776 0.8651140816739888 1.005974716352904 1.0441365572155836 0.7901753191888402 1.0 16.255156437016502 -5.492638702841531 4.468145943872608 0.9633269929429777 1.1995023742594613 0.5490532653505436 0.08754262220142166 0.14031561795099656 6.597655415275721 0.02239317144450464 0.04591614741607728 3.2163351512989642e-06 5.492638702841531 0.23617538131648352 ETPAAQS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 2 ETPAAQSPTR 10 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6 A0A087WVP4 SMTN Smoothelin 1 ET(0.014)PAAQS(0.785)PT(0.201)R;ET(0.021)PAAQS(0.927)PT(0.052)R 75.73899999999999 0.024094 8982500.0 25288.4 38083.0 37623.0 45938.0 48729.0 44691.0 28439.0 47931.0 30691.0 35072.0 True False 33329.58516860368 50392.58499634515 37124.09443756853 35347.703835024986 41963.819473766474 41896.46470511365 30970.015906356923 40524.365294807445 32313.263603081665 33844.139955085986 0.9847963403069138 1.4889604245585895 1.0969135125559497 1.0444261216841189 1.2399138973380912 1.237923751666131 0.9150776455674966 1.197382038621359 0.9547668708959388 1.0 15.046618435222292 -7.2448893117768325 24.99249317294175 1.0332551332092637 1.1885916440120832 0.23085752626237843 0.14634890669739933 1295.5513133039128 1956433.1820044315 0.05448562463414709 0.042079250913743385 5.689979323288252e-08 7.2448893117768325 0.15533651080281952 ETPAAQS(ph)PTRGPSDTK ddPTM_PC-9_AZD4547_30min_R2 2 ETPAAQSPTRGPSDTK 16 1 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6 A0A087WVP4 SMTN Smoothelin 1 ETPAAQS(0.957)PT(0.037)RGPS(0.006)DTK;ET(0.001)PAAQS(0.577)PT(0.357)RGPS(0.061)DT(0.004)K 145.04 0.00014241 9408100.0 19832.7 17405.5 24847.0 36486.0 28606.0 24833.0 22026.7 25244.0 21602.5 26566.0 True False 26139.086054213254 23031.487491896274 24517.512545258603 28074.716403080725 24634.550675502564 23280.18858432541 23987.03362862801 21343.119849411003 22744.364047622174 25635.932426061067 1.019626890092778 0.8984064674972713 0.956372958774634 1.0951314715801181 0.9609383527029227 0.9081077371174201 0.9356801707061447 0.8325470474291756 0.887206428446528 1.0 14.645879751713766 -6.686982383510973 4.143390393664629 0.9032419710144899 0.9877036069354957 0.2664668538703364 0.06112060356066397 0.2937769943731984 9.718731200494974 0.02159667428513159 0.02115347897611755 2.0559739917218258e-07 6.686982383510973 0.08446163592100586 ETPAAQS(ph)PTRGPSDTK ddPTM_PC-9_Lapatinib_30min_R1 1 ETPAAQSPTRGPSDTK 16 1 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6 A0A087WVP4 SMTN Smoothelin 1 ETPAAQS(1)PTRGPSDTK 187.04 2.5373000000000004e-07 3325000.0 11316.0 9325.7 9014.4 8919.4 10035.0 9485.2 7279.5 7508.3 9766.7 8186.1 True False 11154.631764899746 9304.106914619304 8273.270828590275 9575.362430246161 9444.761029569083 9079.54010708115 7656.396891132944 7857.163028396748 8666.671398089547 9601.05647770739 1.161812951605856 0.9690711575567157 0.861704214301823 0.9973238312345222 0.9837210156505997 0.9456813558135873 0.7974535832499543 0.8183644213155319 0.9026789310335395 1.0 13.228977450005033 -7.050209614525513 5.557943637769444 0.8644786869479517 0.9844173189261107 0.2757373415193729 0.08568492091489366 0.27248329688766587 19.460510563784734 0.0331711956944858 0.026084608253407787 8.908208749555975e-08 7.050209614525513 0.11993863197815902 ETPAAQSPTRGPSDT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 ETPAAQSPTRGPSDTK 16 1 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6 A0A087WVP4 SMTN Smoothelin 1 ETPAAQS(0.227)PT(0.108)RGPS(0.004)DT(0.662)K 93.839 0.027649 4129400.0 14516.0 11478.0 13590.0 12254.0 11643.0 12451.0 9893.9 9170.8 11103.0 10281.0 True False 14308.99917809163 11451.423396206214 12472.682658917052 13155.200038145673 10958.181631018728 11918.499754698614 10406.1577307755 9596.908847651393 9852.463220226713 12058.057151428604 1.1866753489716493 0.9496905888233812 1.034385763998417 1.0909883634601187 0.9087850134895433 0.9884262120358706 0.863004512260303 0.7958918030600294 0.8170854638103471 1.0 13.557709851978323 -6.716077259488967 1.1129076131202718 0.8531023151993067 1.0584630914990838 0.4916465790317215 0.08310295936331893 0.39770219081078967 1.0490125337095801 0.04225003990769462 0.03991068374297727 1.9227496479593046e-07 6.716077259488967 0.20536077629977711 ETPAATEAPSSTPK ddPTM_PC-9_Lapatinib_30min_R1 1 ETPAATEAPSSTPK 14 0 P80723;P80723-2 P80723 BASP1 Brain acid soluble protein 1 0 101.35 0.0079777 4888600.0 15260.0 13517.0 16741.0 18007.0 18216.0 16144.0 17826.0 13346.0 15775.0 15096.0 False True 15042.38960165873 13485.702216982005 15364.619602128796 19331.294849591075 17144.570694033933 15453.558753502093 18748.943056712127 13966.103881968358 13998.253381885648 17705.32348584441 0.8495969934514486 0.7616749972269055 0.8677966044739578 1.0918351683913965 0.9683285768679232 0.872819904468697 1.0589438296172393 0.7888081736057748 0.7906239834068776 1.0 14.11189558233844 -5.525396916522944 24.99761696076495 0.9370235064241074 0.8079109209716938 0.23403230913559103 0.09755791053359887 110.55491215757843 1097462.117358902 0.027636389332850172 0.04824481292335411 2.982655422462551e-06 5.525396916522944 -0.12911258545241355 ETPHS(ph)PGVEDAPIAK ddPTM_PC-9_AZD4547_30min_R2 6 ETPHSPGVEDAPIAK 15 0 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 ET(0.001)PHS(0.999)PGVEDAPIAK;ETPHS(1)PGVEDAPIAK;ETPHS(1)PGVEDAPIAK;ET(0.002)PHS(0.998)PGVEDAPIAK;ET(0.006)PHS(0.994)PGVEDAPIAK;ETPHS(1)PGVEDAPIAK 213.02 8.0456e-18 4468570000.0 1683799.0 1553644.0 2144849.0 2735305.0 2333116.0 2163774.0 1973472.0 2355509.0 2015126.0 2146372.0 True False 2219212.0568050817 2055829.0398356665 2116406.900840562 2104722.692290978 2009203.1159136517 2028472.8697241682 2149107.184878161 1991519.2082620088 2121641.446398737 2071228.169584792 1.0714474095096704 0.9925652180791783 1.0218125322546316 1.016171334089619 0.970053973491692 0.9793575133399258 1.037600403681735 0.9615160886215824 1.0243397987504441 1.0 20.982055061074952 -4.757864147463841 24.989671143179667 0.9998988234058825 1.0714475109949713 0.44776843936063926 0.023671635817709605 93.34104362069733 652323.7586375545 0.0057005540162851425 0.04083904909116276 1.746368352507206e-05 4.757864147463841 0.07154868758908872 ETPHS(ph)PGVEDAPIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 ETPHSPGVEDAPIAK 15 0 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 ET(0.002)PHS(0.998)PGVEDAPIAK;ET(0.018)PHS(0.982)PGVEDAPIAK;ET(0.016)PHS(0.984)PGVEDAPIAK;ET(0.003)PHS(0.997)PGVEDAPIAK;ET(0.022)PHS(0.978)PGVEDAPIAK;ET(0.001)PHS(0.999)PGVEDAPIAK 173.77 2.5759000000000002e-05 2947332000.0 808758.0 824431.0 1065330.0 1134411.0 1231631.0 1130848.0 1223328.0 1126818.0 1029404.0 822387.0 True False 945664.7557013773 906275.0612053359 1090731.5074865217 1070853.629480082 990301.7468871085 1071544.3401358712 1107445.5157122577 1097240.2214623608 1044457.0860589654 971479.2530880906 0.973427639031245 0.932881539491979 1.1227532693254725 1.102291815369299 1.0193750857150947 1.103002803950469 1.1399579684197725 1.1294530665215006 1.075120320623314 1.0 19.88982366037967 -5.258753003550731 24.99771025511441 1.091783705895364 0.9531545779915753 0.5889013887718257 0.04438700844648142 147.58924101580968 1373352.29889654 0.011443036416507579 0.027629958463406264 5.511210465524386e-06 5.258753003550731 -0.13862912790378878 ETPHS(ph)PGVEDAPIAK ddPTM_PC-9_Lapatinib_30min_R1 8 ETPHSPGVEDAPIAK 15 0 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 ET(0.006)PHS(0.994)PGVEDAPIAK;ETPHS(1)PGVEDAPIAK;ET(0.008)PHS(0.992)PGVEDAPIAK;ET(0.006)PHS(0.994)PGVEDAPIAK;ET(0.002)PHS(0.998)PGVEDAPIAK;ET(0.264)PHS(0.736)PGVEDAPIAK;ET(0.007)PHS(0.993)PGVEDAPIAK;ETPHS(1)PGVEDAPIAK 236.03 6.204e-32 3739790000.0 1346246.7 1076309.1 1322730.4 1116567.6 1292835.7 1233688.2 1147481.6 1137520.6 1367253.8 1053131.8 True False 1327048.9751865892 1073816.9724071852 1213980.6123989993 1198683.7060643216 1216793.6459387802 1180926.231553657 1206892.5825774109 1190373.959799117 1213259.2792232032 1235164.2284200822 1.0743907123055516 0.869371819309179 0.9828495551169101 0.9704650430150301 0.9851270122153714 0.9560884329237724 0.9771110228161043 0.9637373981610063 0.982265557330058 1.0 20.236271445769937 -8.557145944750554 3.677347966899708 0.9999733397843724 0.9693396009928064 0.02867227610122025 0.04661841854702354 0.8375730717438532 33.32629581553871 0.04118291548717338 0.010834583940855345 2.772388286434146e-09 8.557145944750554 -0.030633738791566056 ETPQGELRPEVVEDEVPRS(ph)PVAEEPGGGGSSSSEAK ddPTM_PC-9_AZD4547_30min_R2 1 ETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAK 36 2 Q7L8J4 Q7L8J4 SH3BP5L SH3 domain-binding protein 5-like 1 ET(0.001)PQGELRPEVVEDEVPRS(0.99)PVAEEPGGGGS(0.003)S(0.003)S(0.001)S(0.001)EAK 58.611999999999995 0.00010386 6566000.0 4538.1 4039.2 5877.1 8159.1 7768.0 6289.9 4793.0 5976.8 6092.9 5711.3 True False 5981.121401656115 5344.792409138913 5799.165813971081 6278.145551838401 6689.547285440251 5896.591558673883 5219.56771472867 5053.2228932007465 6414.958255098118 5511.349125384422 1.0852372559938173 0.9697793203703292 1.0522225469733026 1.139130439572814 1.2137767238568193 1.0698998420396004 0.9470580788809309 0.9168758462290808 1.1639542531522475 1.0 12.428189804593739 -7.021947692199885 23.098950752926257 1.001249830863653 1.0912623595078483 0.18727386694831705 0.08375539777845153 512.6041907260491 539490.8482621748 0.03374910924011807 0.026432097088525022 9.50719294397571e-08 7.021947692199885 0.09001252864419529 ETPQGELRPEVVEDEVPRS(ph)PVAEEPGGGGSSSSEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAK 36 2 Q7L8J4 Q7L8J4 SH3BP5L SH3 domain-binding protein 5-like 1 ETPQGELRPEVVEDEVPRS(0.999)PVAEEPGGGGSSSSEAK;ET(0.013)PQGELRPEVVEDEVPRS(0.978)PVAEEPGGGGS(0.003)S(0.003)S(0.001)S(0.001)EAK;ETPQGELRPEVVEDEVPRS(0.977)PVAEEPGGGGS(0.007)S(0.007)S(0.008)S(0.002)EAK 73.27600000000001 3.6602e-07 21015200.0 25770.0 23734.0 29069.8 27591.0 36955.1 35907.4 34512.7 31523.0 37220.5 25888.8 True False 30132.352019299415 26090.15466745841 29762.93427983043 26045.16572122891 29714.013439405047 34024.35273263496 31243.407205690106 30695.554651379345 37764.77939823206 30582.23450437198 0.9852894174554756 0.8531147278897692 0.973209929299822 0.8516436468206907 0.9716102803134672 1.1125528688157467 1.0216195026960377 1.0037054240425487 1.2348600424482807 1.0 14.900406201244982 -6.582163738370836 4.957267875150031 1.0705704543830115 0.9147306719045889 0.49896241702085586 0.07545313388593615 0.16730393757373108 8.392030876641707 0.02409946638171654 0.024301033314985128 2.617196082908331e-07 6.582163738370836 -0.15583978247842256 ETPRPEGGSPSPAGT(ph)PPQPK ddPTM_PC-9_AZD4547_30min_R2 2 ETPRPEGGSPSPAGTPPQPK 20 1 Q9BR39 Q9BR39 JPH2 Junctophilin-2 1 ETPRPEGGSPSPAGT(1)PPQPK;ETPRPEGGSPSPAGT(1)PPQPK 107.25 8.424100000000001e-05 14880500.0 39021.0 37947.0 58317.0 61657.0 57213.0 41283.0 41788.0 42752.0 36881.0 35780.0 True False 51428.866312779195 50212.625655970085 57543.678476349094 47442.93124115405 49269.96251826637 38701.56748386044 45507.05104591733 36145.660743226865 38830.454365946236 34527.35309058439 1.4895108286422296 1.4542854045091302 1.666611347976201 1.3740680067969573 1.4269834814445217 1.1208958700750902 1.3179999905155517 1.0468703073877907 1.1246287621316475 1.0 15.075452119201035 -6.880736781070541 0.7022636666172546 1.0441042153437785 1.5443500015310059 0.7759555431033645 0.0984848868925003 0.32333645682535184 0.34326538492879033 0.0733509748208842 0.06633906524809761 1.3160222105119967e-07 6.880736781070541 0.5002457861872274 ETPRPEGGSPSPAGT(ph)PPQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ETPRPEGGSPSPAGTPPQPK 20 1 Q9BR39 Q9BR39 JPH2 Junctophilin-2 1 ETPRPEGGSPS(0.006)PAGT(0.994)PPQPK;ETPRPEGGSPSPAGT(1)PPQPK 125.77 2.5449e-06 7778900.0 39985.0 38767.0 35044.9 36090.9 44946.0 41716.0 39774.0 27916.9 36263.0 33315.7 True False 46753.67076025173 42615.531557822556 35880.50332452335 34068.84388127654 36139.153947560655 39528.33952317904 36006.3187811767 27184.110955400578 36793.27777214409 39355.572683063925 1.1879809534666348 1.0828334757319262 0.9117007040775189 0.8656675931420901 0.9182728514356645 1.004389895212717 0.9148975945831294 0.690730920734355 0.9348937206033218 1.0 15.264280312943994 -5.107640658338175 2.3766588087851104 0.8949343003925762 1.1883897527738292 0.5665716830278029 0.08275136124567016 0.24831186230880717 2.487218808505993 0.02333887130420667 0.11099400066690925 7.804756204775736e-06 5.107640658338175 0.29345545238125303 ETPRPEGGSPSPAGT(ph)PPQPK ddPTM_PC-9_Lapatinib_30min_R1 2 ETPRPEGGSPSPAGTPPQPK 20 1 Q9BR39 Q9BR39 JPH2 Junctophilin-2 1 ETPRPEGGSPSPAGT(1)PPQPK;ETPRPEGGSPSPAGT(1)PPQPK 112.47 2.8942e-05 12025600.0 44703.0 40997.0 29089.0 19858.5 29965.0 30372.0 28408.0 28930.0 40010.0 16892.0 True False 44065.527022473834 40902.073965348194 26697.414706787196 21318.96033601402 28202.517613456683 29073.060360590036 29878.82723858845 30274.193414157402 35503.65247602185 19811.759692824828 2.2242106559788795 2.06453513466356 1.3475539336597206 1.0760760612160591 1.4235241114735868 1.46746481944859 1.508135960755146 1.5280920969943788 1.7920494204702127 1.0 14.274069406539295 -5.206506040901083 4.769313054497585 1.407726954041579 2.1738362367503163 0.6619542479027032 0.21524652760561172 0.12744317364064026 6.241998006507275 0.05696691892170249 0.15823262910087565 6.2157560176921655e-06 5.206506040901083 0.7661092827087372 ETPS(ph)QENGPTAK ddPTM_PC-9_AZD4547_30min_R2 2 ETPSQENGPTAK 12 0 O15355 O15355 PPM1G Protein phosphatase 1G 1 ET(0.013)PS(0.971)QENGPT(0.017)AK;ET(0.015)PS(0.985)QENGPTAK 148.48 0.00014933 12380800.0 33341.0 30146.0 48348.0 48411.0 42657.0 44129.0 40439.0 47067.0 40327.0 45663.0 True False 43942.74446411856 39890.10496283959 47706.873929978006 37250.59189249412 36734.81186341723 41369.60665395628 44037.992659276606 39793.876642062554 42458.602890797774 44064.35226873551 0.9972402225754892 0.9052692915933858 1.0826636833108956 0.845367966952373 0.8336628129555254 0.9388452234962001 0.9994017928756075 0.9030854782426262 0.9635589928079564 1.0 15.42732437768449 -10.331334361401044 17.466070247632548 0.999999999999999 0.9386936075940869 0.05745364747034154 0.07112323794421524 0.0 0.0 0.06976378576477611 0.016920203385360804 4.663002395892522e-11 10.331334361401044 -0.06130639240591207 ETPS(ph)QENGPTAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ETPSQENGPTAK 12 0 O15355 O15355 PPM1G Protein phosphatase 1G 1 ET(0.007)PS(0.993)QENGPTAK;ETPS(1)QENGPTAK;ET(0.002)PS(0.998)QENGPTAK 146.59 3.2111e-07 9089200.0 48041.2 56656.0 64794.0 65280.9 66091.0 52781.8 61530.5 54138.5 56450.3 42217.9 True False 56173.62630304878 62280.433253540235 66338.93469261343 61623.422816533384 53140.94298821323 50013.8294909515 55701.88559775721 52717.42173948228 57275.77884402461 49871.67107328746 1.1263634262525606 1.2488138438757714 1.3301927379799843 1.2356398229763843 1.0655536869843705 1.0028504843452135 1.1169043346452563 1.057061466057813 1.148463197871526 1.0 15.605932924416395 -6.254455953224081 7.313393639339146 1.06729372597035 1.2433819863178743 0.6386868945025105 0.06255940090770301 0.08921955490000477 34.8281699718574 0.019152067066783556 0.023546767765525584 5.566010826843377e-07 6.254455953224081 0.17608826034752423 ETPS(ph)QENGPTAK ddPTM_PC-9_Lapatinib_30min_R1 4 ETPSQENGPTAK 12 0 O15355 O15355 PPM1G Protein phosphatase 1G 1 ETPS(1)QENGPTAK;ETPS(1)QENGPTAK;ET(0.004)PS(0.996)QENGPTAK;ET(0.002)PS(0.998)QENGPTAK 173.25 2.0757e-12 9977100.0 49181.0 48972.8 56695.0 44729.1 52797.0 46968.0 44546.0 37074.2 48691.0 36286.4 True False 48479.6699213092 48859.406490479865 52033.75594902887 48018.627225903474 49691.58426289578 44959.28812775557 46852.37391474804 38796.802678021224 43206.90684103928 42558.45589141126 1.1391313172875923 1.1480540228044365 1.2226420075435545 1.1282981541535235 1.167607781393311 1.056412578559478 1.100894591530595 0.9116120842591666 1.0152367123300374 1.0 15.377158187385369 -7.225239558397048 1.240356173803011 0.9759196602211554 1.1644254161530028 0.7261478042293807 0.04610352998658248 0.226031533900298 0.6818503461274028 0.02802761747827678 0.016595459875743405 5.953336647532288e-08 7.225239558397048 0.18850575593184737 ETPSSSPAS(ph)PQETR ddPTM_PC-9_Lapatinib_30min_R1 2 ETPSSSPASPQETR 14 0 Q9BX66-4;Q9BX66-9;Q9BX66-8;Q9BX66-10;Q9BX66-6;Q9BX66-5;Q9BX66-12;S4R406;Q9BX66-7;Q9BX66-3;Q9BX66-2;Q9BX66-11;Q9BX66 Q9BX66-4 SORBS1 Sorbin and SH3 domain-containing protein 1 1 ETPSSS(0.066)PAS(0.933)PQETR;ETPS(0.001)S(0.001)S(0.057)PAS(0.839)PQET(0.103)R 114.69 0.0020180999999999997 0.0 8893.5 9447.4 10524.2 9033.0 10860.1 12083.900000000001 11308.9 9003.099999999999 11547.900000000001 9909.8 True False 8766.67705913184 9425.52512574652 9658.940900586818 9697.316953204647 10221.330269778102 11567.099765946718 11894.41950712733 9421.416893432433 10247.253897222025 11622.69572602152 0.7542722674486375 0.8109586061557256 0.8310413632322714 0.8343431835261563 0.8794285345433275 0.9952166036704951 1.0233787227602853 0.8106051397645432 0.8816589661105829 1.0 13.50465710057372 -6.280980403355374 2.1390726861249196 0.9348649223206906 0.8024018814107048 0.5109970194276121 0.06178434374028101 0.3083405588836747 2.7701762108948706 0.022770937885738567 0.028966574537822587 5.236240635108244e-07 6.280980403355374 -0.13246304090998584 ETQPWS(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 1 ETQPWSSPK 9 0 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 ETQPWS(0.713)S(0.287)PK 73.632 0.029071 5143800.0 55450.0 80686.0 57967.0 71715.0 68644.0 66967.0 67167.0 64687.0 61424.0 53622.0 True False 54659.27283171538 80499.17652433294 53201.17701909083 76989.16033422691 64606.49487929649 64102.97751770154 70644.57860934493 67692.59417150372 54505.78229660504 62890.491253176195 0.8691182362000535 1.2799896283250523 0.8459335578238781 1.224178072076018 1.0272855815231627 1.0192793257035357 1.1232950673727982 1.0763565814583298 0.8666776361657423 1.0 15.940554284429835 -8.245577297338752 24.18709949867588 0.9333388176250955 1.0638756540718908 0.12437270907993303 0.13180776299791708 847.8038285041706 1292770.4200005746 0.08109978304898392 0.030415678660424352 5.6809727050709324e-09 8.245577297338752 0.13053683644679526 ETQPWSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 ETQPWSSPK 9 0 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 ETQPWS(0.227)S(0.773)PK 109.39 0.002372 5594900.0 52126.0 75345.0 51479.0 74005.0 67886.0 74985.0 67844.0 72391.0 65928.0 49233.0 True False 51382.67368126234 75170.54328168303 47246.59533468657 79447.5745734431 63893.07894901114 71778.06634857242 71356.63035675854 75754.55013633841 58502.49438738247 57742.858451151136 0.889853309301109 1.3018154157587338 0.8182240471288045 1.3758857234380517 1.1065104960652914 1.2430639610488747 1.2357654655618457 1.3119293392866005 1.0131554958761517 1.0 15.817354906784349 -4.742504069876471 24.715868292808473 1.1659508901786906 0.8898522602509255 0.18926671105307646 0.1643153347980453 1798.6026117797703 2347536.8652806357 0.03834391948925831 1.3365508776325299 1.8092389553675307e-05 4.742504069876471 -0.2760986299277651 ETQS(ph)PEQVK ddPTM_PC-9_AZD4547_30min_R2 7 ETQSPEQVK 9 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 ET(0.201)QS(0.799)PEQVK;ETQS(1)PEQVK;ET(0.04)QS(0.96)PEQVK;ETQS(1)PEQVK;ET(0.005)QS(0.995)PEQVK;ET(0.022)QS(0.978)PEQVK;ET(0.367)QS(0.633)PEQVK 137.4 0.0009472999999999999 1337537600.0 263884.0 273763.0 327301.0 332247.0 330161.0 323987.0 320960.0 400701.0 304177.0 306497.0 True False 347793.62287182256 362251.53602275136 322960.774885326 255652.58731497976 284323.84414369764 303728.0416731711 349524.8182180925 338781.86764295894 320255.17523034674 295766.6333204261 1.1759055406869772 1.2247883811501388 1.0919445890822932 0.8643726455715922 0.9613114263489904 1.0269178719159975 1.1817587883195266 1.1454363997710695 1.0827968376114636 1.0 18.17409977955002 -5.40631113125811 4.97350421813118 1.0415695557260127 1.1975863512186897 0.3575030694845779 0.0857886349106498 0.2762980892920874 10.043597235880835 0.02615289754279334 0.05610642069610949 3.923637428707645e-06 5.40631113125811 0.156016795492677 ETQS(ph)PEQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 ETQSPEQVK 9 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 ET(0.069)QS(0.931)PEQVK;ETQS(1)PEQVK;ET(0.081)QS(0.919)PEQVK;ET(0.053)QS(0.947)PEQVK;ET(0.029)QS(0.971)PEQVK;ET(0.002)QS(0.998)PEQVK 145.23 0.00050495 998190700.0 425029.0 529018.0 472964.0 492588.0 515763.0 419356.0 486964.0 392115.0 366631.0 334514.0 True False 496978.0149945994 581535.4108818354 484241.2554859578 464989.8913518422 414702.94258567435 397364.2331259531 440835.24460594665 381822.39673018525 371992.2847772919 395158.74018863286 1.2576667664173697 1.4716501287665655 1.2254347588384367 1.1767167066325668 1.049459117082193 1.0055812834514744 1.1155902673328437 0.9662506681439429 0.9413743059301124 1.0 18.592072792734008 -5.899387192943125 1.275404998346254 1.006472299992536 1.3696306942260976 0.8051689847695775 0.06908483465115273 0.18887519586881346 0.6213065152381758 0.024506147244616003 0.0519046712037472 1.2607030602752535e-06 5.899387192943125 0.36315839423356167 ETQS(ph)PEQVK ddPTM_PC-9_Lapatinib_30min_R1 8 ETQSPEQVK 9 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 ET(0.001)QS(0.999)PEQVK;ET(0.283)QS(0.717)PEQVK;ET(0.246)QS(0.754)PEQVK;ET(0.017)QS(0.983)PEQVK;ET(0.002)QS(0.998)PEQVK;ETQS(1)PEQVK;ET(0.293)QS(0.707)PEQVK;ET(0.003)QS(0.997)PEQVK 151.98 0.00012943 834847200.0 248765.0 281646.0 280836.0 275141.0 296226.0 284856.0 279805.0 278063.0 294268.0 235464.0 True False 245217.5654820861 280993.8659912788 257746.74813830986 295375.7869834693 278802.5690827234 272673.3729117682 294291.9338036206 290982.82209888875 261124.4390605847 276163.6386639414 0.8879429843422905 1.0174904536698084 0.9333116748651956 1.069567986620088 1.009555676596488 0.9873616028197671 1.065643309261793 1.0536608784076043 0.9455424339130408 1.0 18.075163852785323 -3.7137919232273093 1.079343731925482 1.0166399019932975 9.764363256235937e-13 0.38059727750057415 0.04484322798483278 15.057487783153992 2.42643845332662 0.013425309713981913 29.812720224168704 0.00019328941727805784 3.7137919232273093 -1.0166399019923211 ETQS(ph)PEQVKSEK ddPTM_PC-9_AZD4547_30min_R2 2 ETQSPEQVKSEK 12 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 ET(0.034)QS(0.966)PEQVKSEK;ET(0.001)QS(0.999)PEQVKSEK 93.228 0.018737 377969000.0 74271.0 46005.7 83091.0 145244.0 110209.0 77393.0 68729.0 67644.0 55619.0 90443.0 True False 97887.63306723122 60876.14283450242 81989.15904930515 111760.23979743058 94908.38269581438 72553.60347548424 74845.74785428493 57191.174104482525 58558.906791561014 87276.6180987069 1.1215791262274122 0.6975080400761354 0.9394172326496221 1.2805289919808023 1.0874434042400247 0.8313063115418676 0.8575692950159564 0.6552863223893626 0.6709575607676832 1.0 16.413307578979612 -6.899307063092321 4.608515624201788 0.7765270888849939 1.0157768180812488 0.30596305297505866 0.16629479659966956 0.28573098514845235 10.455973861425507 0.06417586577837714 0.05630549503652179 1.2609356887619016e-07 6.899307063092321 0.23924972919625487 ETQS(ph)PEQVKSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETQSPEQVKSEK 12 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 ET(0.016)QS(0.984)PEQVKSEK 64.945 0.020194 193830000.0 53393.0 23322.0 33331.0 76163.0 59509.0 72549.0 60445.0 71464.0 57140.0 44922.0 True False 62431.380340180534 25637.254030271557 34125.737448521395 71895.83403377765 47848.638638930875 68744.40272478465 54719.212016096644 69588.14572236701 57975.56440174044 53066.002997643685 1.1764854485639837 0.48312012554271216 0.6430809844494355 1.3548379371434867 0.9016816028344083 1.2954509260446305 1.0311538258972768 1.3113508044963735 1.0925180176904365 1.0 15.695500266670166 -5.75152882522349 24.99221741391731 1.145859028416905 0.7391179049320045 0.38875411238330193 0.2136319365925877 184.3579090668848 464905.1615375957 0.05493450771947489 0.09370960242721757 1.772030427089333e-06 5.75152882522349 -0.40674112348490055 ETQS(ph)PEQVKSEK ddPTM_PC-9_Lapatinib_30min_R1 3 ETQSPEQVKSEK 12 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 ET(0.007)QS(0.993)PEQVKSEK;ET(0.04)QS(0.96)PEQVKSEK;ET(0.003)QS(0.997)PEQVKSEK 201.3 1.5805999999999997e-05 152941000.0 154584.0 68925.0 98956.0 87128.0 77680.0 75222.0 51566.0 50571.0 85435.0 54337.0 True False 152379.60381276606 68765.40839723925 90820.21966120624 93535.68377048742 73111.01512475604 72004.93041104647 54235.83516562422 52920.713278512085 75812.41062956574 63729.0780504986 2.391053008675588 1.0790271960744495 1.4250985961108797 1.467708095453228 1.1472159548083096 1.1298599103221 0.8510374984971227 0.8304013630414985 1.1896046977094563 1.0 15.959664169413038 -2.9684799223897476 1.411311811753189 1.1059011249279302 199.9999999556142 0.7571188282728339 0.2111508255234094 119.63318269775476 1.9866722051517425 0.06574109127050426 75488.0205066845 0.0010752763097041115 2.9684799223897476 198.89409883068626 up ETQSPEQVKS(ph)EK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETQSPEQVKSEK 12 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 ET(0.02)QS(0.309)PEQVKS(0.671)EK 121.45 0.002924 0.0 8529.7 4162.5 5427.8 10499.0 9559.5 10510.0 10566.0 12013.0 11249.0 8543.7 True False 9973.609740745755 4575.725490995855 5557.219337046133 9910.775068217255 7686.384598444941 9958.837098202419 9565.11198878446 11697.671478825627 11413.495343982815 10092.605178108013 0.9882096410924334 0.45337407044527156 0.5506228807107566 0.9819838280917629 0.7615857811536675 0.9867459315464205 0.9477346849485656 1.1590338938651026 1.1308770275428945 1.0 13.30101100121 -6.661192780534623 0.8836620530014117 1.0971684332163743 0.6690932628855301 0.4706195591295066 0.16191797443889291 0.48751597017657083 0.833949324656946 0.09714633416354962 0.10068305955670367 2.1817612270492049e-07 6.661192780534623 -0.4280751703308442 ETQST(ph)PQSAPQVR ddPTM_PC-9_AZD4547_30min_R2 2 ETQSTPQSAPQVR 13 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 ETQS(0.094)T(0.906)PQSAPQVR;ETQS(0.172)T(0.826)PQS(0.002)APQVR 148.41 0.00028250000000000004 3728600.0 18394.9 18089.3 26094.0 33858.0 28101.0 30567.0 19143.0 39235.0 27468.0 25613.0 True False 24244.095562311108 23936.312469458448 25747.976510483295 26052.56120088546 24199.661208568046 28655.64065787764 20846.689915095132 33172.1322806069 28919.90240296659 24716.296665990452 0.9808951514840372 0.9684425135742418 1.0417408747934487 1.0540641081045812 0.9790973759376624 1.1593824530075216 0.8434390554868243 1.342115800311284 1.1700742548037257 1.0 14.593174974658456 -7.764793791988226 24.999995235030408 1.1920712209862843 1.0109196955456696 0.3275699481484249 0.10793956969160719 89.91478473406133 670099.8525557035 0.05242261832617048 0.026793576822448557 1.7187242634837924e-08 7.764793791988226 -0.18115152544061464 ETQST(ph)PQSAPQVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETQSTPQSAPQVR 13 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 ETQS(0.004)T(0.982)PQS(0.014)APQVR 113.69 0.00080496 0.0 12921.0 11158.0 14748.0 12940.0 16185.0 14266.0 15027.0 12365.0 9624.5 9652.1 True False 15108.27009861729 12265.692499346967 15099.648252101462 12215.013752046028 13013.665434994648 13517.865846142307 13603.533773941324 12040.431851800455 9765.240104734876 11401.949324018447 1.3250602742805915 1.0757539917765664 1.3243041012551893 1.0713092476489825 1.141354435559636 1.1855749803822262 1.1930884261417645 1.0559976640517978 0.8564535613365858 1.0 13.476992874086951 -7.9774895102135615 3.5272410318765157 0.9303623040121156 1.182107565635292 0.5857087593968842 0.08780305397344522 0.15499369506197058 4.0171536527644784 0.05593167000574599 0.022042939087795806 1.0531991254001558e-08 7.9774895102135615 0.25174526162317634 ETQST(ph)PQSAPQVR ddPTM_PC-9_Lapatinib_30min_R1 2 ETQSTPQSAPQVR 13 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 ETQS(0.07)T(0.93)PQSAPQVR;ET(0.001)QS(0.106)T(0.882)PQS(0.011)APQVR 209.39 2.1228999999999995e-60 0.0 31007.0 28176.0 36765.0 25904.0 25065.0 23246.0 17840.1 16211.2 23054.0 19690.5 True False 30564.834494012604 28110.760203128277 33742.323617004084 27809.066573210832 23590.72597968603 22251.8227690727 18763.773085720284 16964.43153389522 20457.41575061756 23093.976689057985 1.3234981097254828 1.2172334189826763 1.4610876277965297 1.2041696823218357 1.0215099069907438 0.9635336117584158 0.8124964071090723 0.7345825174376759 0.8858333939650318 1.0 14.49522900028373 -6.427058436988396 1.530853940449772 0.8456342205867254 1.3261770509803092 0.8348789037108684 0.08973166392356591 0.1444915077168996 0.6832516178328351 0.035137660007527716 0.0418849495367762 3.7406025278252606e-07 6.427058436988396 0.4805428303935838 ETQSTPQS(ph)APQVR ddPTM_PC-9_AZD4547_30min_R2 1 ETQSTPQSAPQVR 13 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 ETQS(0.002)T(0.081)PQS(0.917)APQVR 144.88 4.3448e-05 7858500.0 10686.0 13116.0 22854.0 33181.0 30090.0 24225.0 25199.0 33396.0 28651.0 28322.0 True False 14083.925717392118 17355.490502640638 22550.94102746166 25531.633091339718 25912.52289120717 22710.20692043987 27441.66218306861 28235.415563735125 30165.433367824233 27330.455400545885 0.5153198331671712 0.6350238314102146 0.8251213050409412 0.9341824977724213 0.9481189578234984 0.8309487195733396 1.0040689692466853 1.0331117850005223 1.1037296278356827 1.0 14.738221878877653 -4.505557401976363 0.5286380854922678 1.022643354959076 5.246638020387923e-20 0.8877670819712715 0.05890895740376682 1.8831292343804766 0.32524273579168533 0.03739068568849225 1.2662073926192488 3.12206972583209e-05 4.505557401976363 -1.022643354959076 ETQSTPQS(ph)APQVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETQSTPQSAPQVR 13 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 ETQSTPQS(1)APQVR 136.14 5.4000000000000005e-05 7611500.0 3125.6 9836.5 14871.0 13559.0 18779.0 14423.0 13070.0 11458.0 14429.0 15190.0 True False 3654.70234658604 10813.002712836207 15225.581038581566 12799.333188871115 15099.389756179446 13666.632489759602 11831.914981394377 11157.239640754513 14639.996828013866 17943.826756026163 0.2036746339717454 0.6026029374812607 0.8485136000027578 0.7133000871496183 0.8414810263985938 0.761634219700091 0.6593863807462813 0.6217870798940657 0.8158793008351601 1.0 14.131199976228244 -4.808647557680479 2.810086058670507 0.7632537118241516 0.119704208120105 0.7410190222566186 0.10337129743708812 0.1973153238202289 2.2538632158454703 0.025935684619884453 0.28856919900496153 1.5536473274752655e-05 4.808647557680479 -0.6435495037040466 down ETQSTPQS(ph)APQVR ddPTM_PC-9_Lapatinib_30min_R1 2 ETQSTPQSAPQVR 13 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 ETQS(0.036)T(0.336)PQS(0.628)APQVR;ETQST(0.009)PQS(0.991)APQVR 168.0 0.00012086 14519700.0 60109.0 57426.0 68297.0 62330.0 49044.0 43308.0 41994.0 36470.0 49673.0 28839.0 True False 59251.83463735942 57293.03362524291 62681.884294043964 66913.95612678457 46159.328344213885 41455.81779587889 44168.24384177994 38164.52934028069 44078.30366012083 33823.782724447985 1.7517802523764416 1.6938683083436212 1.8531896566594608 1.9783108433468872 1.3647003565585736 1.225641086143639 1.305833951264562 1.1283341562117828 1.3031748701561057 1.0 15.045750393898997 -6.414646944744172 4.262651231040588 1.2143344343178795 1.8104977112312932 0.8794467633320688 0.1096342089228292 0.07809582779312416 2.390443517481375 0.03541423395501593 0.04002035776955025 3.8490455911707153e-07 6.414646944744172 0.5961632769134138 ETQTHENMSQLS(ph)EEEQNKDYQDCSK ddPTM_PC-9_Lapatinib_30min_R1 1 ETQTHENMSQLSEEEQNKDYQDCSK 25 1 Q9BWU0;A0A087X0M4 Q9BWU0 SLC4A1AP Kanadaptin 1 ETQTHENMS(0.164)QLS(0.544)EEEQNKDY(0.268)QDCS(0.024)K 54.12 0.0030355 7679800.0 17855.0 20303.0 22595.0 17621.0 22793.0 22394.0 17865.0 17823.0 20013.0 17872.0 True False 17600.384425794018 20255.989650912605 20737.32631922227 18916.90712193281 21452.360552762166 21436.260822963693 18789.962285883663 18651.121646060412 17758.92519376721 20961.151387056903 0.8396668723389836 0.9663586354049367 0.9893219096746354 0.9024746194817155 1.0234342644941048 1.0226661898067375 0.896418423726766 0.8897947112569928 0.8472304247911207 1.0 14.355430345221308 -10.392133388391105 4.568181331430297 1.0000004238620246 0.9359578503416884 0.09049498723273497 0.06395500501538502 42860346.37217794 201.91566486507062 197.24724313124833 0.01666453944632057 4.053840074434097e-11 10.392133388391105 -0.06404257352033615 ETQVILLDTPGIIS(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETQVILLDTPGIISPGK 17 0 J3QSB2;J3QRV9;O75616-2;O75616 J3QSB2 ERAL1 GTPase Era, mitochondrial 1 ETQVILLDTPGIIS(1)PGK 139.11 8.527100000000001e-08 0.0 7108.4 7220.6 6428.9 6744.5 6876.5 5447.8 7660.4 7778.6 5147.2 5502.9 True False 8311.711722700347 7937.413448717041 6582.189357739019 6366.627530964023 5529.099188368282 5162.107777696206 6934.751455506763 7574.419992107966 5222.468062454292 6500.532209067566 1.2786201891448785 1.221040553824989 1.0125616097336692 0.9794009669059466 0.8505610018600882 0.7941054073227423 1.0667974917243708 1.1651999787867273 0.8033908447018372 1.0 12.666342123410947 -5.265338931653949 2.2413957814672867 0.9524393627389625 1.2812569584701319 0.5413405421118037 0.10904587923617919 0.27326367862587253 2.550945053618342 0.03225607938701421 0.11574211781307796 5.428265340174489e-06 5.265338931653949 0.3288175957311694 ETS(ph)PESSLIQDEIAVK ddPTM_PC-9_AZD4547_30min_R2 3 ETSPESSLIQDEIAVK 16 0 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 ET(0.032)S(0.927)PES(0.02)S(0.02)LIQDEIAVK;ET(0.03)S(0.97)PESSLIQDEIAVK;ET(0.166)S(0.834)PESSLIQDEIAVK 203.53 7.7459e-17 57263000.0 215000.0 171637.0 230297.0 255941.0 252925.0 252034.0 222054.0 317182.0 233673.0 222901.0 True False 283365.5277221888 227115.30370552992 227243.11130661317 196937.75669903218 217810.7295532925 236274.27413771537 241816.375824403 268168.8100172669 246024.47772711542 215097.30383578458 1.3173829828128547 1.0558723873123042 1.0564665723569517 0.9155751986988351 1.0126148755429287 1.0984529788346316 1.124218535110124 1.2467325495720747 1.1437822480329278 1.0 17.71462991566863 -7.18710126754733 3.1298432317193825 1.150661509301083 1.061425476299568 0.03676691967488632 0.11047208814635023 0.6160291681708921 11.803543429863439 0.048261480304864754 0.035055248661019695 6.499781126310062e-08 7.18710126754733 -0.08923603300151495 ETS(ph)PESSLIQDEIAVK ddPTM_PC-9_Lapatinib_30min_R1 3 ETSPESSLIQDEIAVK 16 0 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 ET(0.155)S(0.844)PES(0.001)SLIQDEIAVK;ET(0.157)S(0.843)PESSLIQDEIAVK;ET(0.103)S(0.895)PES(0.002)SLIQDEIAVK 208.07 3.9969e-17 57947300.0 331034.0 318036.0 343592.0 308225.0 343746.0 365525.0 308904.0 334077.0 331744.0 265615.0 True False 326313.39445579925 317299.607182074 315343.1920634747 330892.89470845816 323527.5361106385 349892.3478303923 324897.53764111997 349599.43702804873 294379.49730081 311526.19884026004 1.047466940727902 1.0185326574885418 1.0122525592949307 1.0621671497944503 1.038524327376178 1.1231554493103968 1.0429220362545375 1.1222152047870342 0.9449590384266773 1.0 18.248993971065048 -4.311381226927989 18.894800975006774 1.0459241895818383 16.370532274170344 0.0 0.0512831929430057 19745.43554841821 1792124.5439401106 0.011874714435610854 209660.58396047863 4.882236048749897e-05 4.311381226927989 15.324608084588506 ETS(ph)PQVK ddPTM_PC-9_AZD4547_30min_R2 2 ETSPQVK 7 0 A0A0C4DG22;Q9GZR2 A0A0C4DG22 REXO4 RNA exonuclease 4 1 ET(0.174)S(0.826)PQVK;ET(0.029)S(0.971)PQVK 101.46 0.011192 28220000.0 267195.0 208340.0 215053.0 202843.0 188606.0 211180.0 206167.0 216314.0 327560.0 330040.0 True False 352157.4519987446 275681.8306892459 212201.256706866 156080.68024310953 162421.31247653734 197974.88121603656 224515.46360159968 182887.6417012154 344874.15287300624 318485.4000563574 1.1057255746619117 0.8656027266570548 0.6662825255704533 0.49007169627081926 0.509980402391432 0.6216136789347456 0.7049474279256465 0.5742418386175713 1.0828570251948104 1.0 18.28086771269838 -10.065767531690108 11.467456137878782 0.9999999977319647 0.714609087823068 0.11932315445138097 0.20843406217448035 0.0 0.0 0.21020438029663335 0.05098205076061901 8.594734556863109e-11 10.065767531690108 -0.2853909099088967 ETS(ph)PQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ETSPQVK 7 0 A0A0C4DG22;Q9GZR2 A0A0C4DG22 REXO4 RNA exonuclease 4 1 ET(0.027)S(0.973)PQVK;ET(0.016)S(0.984)PQVK 85.67 0.019128 26113000.0 111650.0 213362.0 182429.0 121886.0 287950.0 224372.0 141501.0 152592.0 225262.0 228454.0 True False 130550.13981198194 234543.16929966566 186778.79922583513 115057.12257974375 231528.2645663704 212605.537335668 128097.0009014755 148586.6216845885 228556.03059616435 269870.901759131 0.483750337516945 0.8690939548162309 0.6921042543243199 0.4263413425817807 0.8579222993556278 0.7878045982349949 0.47466029151896655 0.5505840782242137 0.8469087593599046 1.0 18.041909904183726 -8.4958716364725 4.525908470487114 0.9991470195468328 0.652130000405901 0.3716892916297774 0.15198234502485083 0.18640277185504397 10.250182679907965 0.14790237442832405 0.03859506302234659 3.192481310806441e-09 8.4958716364725 -0.34701701914093186 ETS(ph)PQVK ddPTM_PC-9_Lapatinib_30min_R1 1 ETSPQVK 7 0 A0A0C4DG22;Q9GZR2 A0A0C4DG22 REXO4 RNA exonuclease 4 1 ET(0.463)S(0.537)PQVK 81.33800000000001 0.02409 16002000.0 52497.0 87532.0 65194.0 76708.0 104360.0 68816.0 124000.0 120670.0 94444.0 77106.0 True False 51748.383153229275 87329.32503195025 59834.0009761176 82349.3622103867 98221.74997965425 65872.90009793118 130420.11326334022 126276.76872749325 83806.72218059005 90433.66936271326 0.5722247423763794 0.9656726930064947 0.6616341170027518 0.9106051185438262 1.0861192592518212 0.7284112273906168 1.4421632361310972 1.3963468431322823 0.9267203550533406 1.0 16.464572382047038 -6.548249825655106 0.9994913046574211 1.1890408143426852 0.7526619253949441 0.3638486373766112 0.21640785360519585 0.5625482517254212 1.21274389297519 0.11254872750805102 0.12811360151295853 2.8297637205674425e-07 6.548249825655106 -0.436378888947741 ETS(ph)RSRGGGGAVS(ph)ER ddPTM_PC-9_AZD4547_30min_R2 1 ETSRSRGGGGAVSER 15 2 Q8N7J2-2;Q8N7J2 Q8N7J2-2 AMER2 APC membrane recruitment protein 2 2 ETS(1)RSRGGGGAVS(1)ER 133.05 0.00011346 11569000.0 38707.0 22644.0 23764.0 44304.0 48790.0 37421.0 24626.0 21972.0 14232.0 21427.0 True False 51015.0208443849 29963.230172445456 23448.873832878224 34090.39728997663 42016.35067670316 35081.05895437692 26817.66629311668 18576.732266330946 14984.274464796144 20676.847251871215 2.4672533594195865 1.4491198685879851 1.13406427717147 1.6487231769287995 2.0320482211281394 1.696634817051335 1.2969901052342365 0.8984315664782883 0.7246885505448659 1.0 14.335728603846361 -7.5475914347778 2.447316915828818 0.8463846579230999 1.7063844636104912 0.5722393096419712 0.3352602982929752 0.23617484770826916 2.8335390710111317 0.19715262091559924 0.10410665720810236 2.834056898661568e-08 7.5475914347778 0.8599998056873913 ETS(ph)RSRGGGGAVS(ph)ER ddPTM_PC-9_Lapatinib_30min_R1 1 ETSRSRGGGGAVSER 15 2 Q8N7J2-2;Q8N7J2 Q8N7J2-2 AMER2 APC membrane recruitment protein 2 2 ET(0.001)S(0.999)RSRGGGGAVS(1)ER 114.71 0.0039172 4407800.0 12578.0 16315.0 17395.0 14273.0 11582.0 16011.0 14643.0 16016.0 18328.0 10007.0 True False 12398.635413477292 16277.22361989061 15964.850246641794 15322.684033332218 10900.769531088103 15326.246853463941 15401.142891250729 16760.161829282566 16263.707637603822 11736.696616510659 1.0563990719531293 1.3868658406823382 1.3602507390523462 1.3055363475764512 0.9287766300232545 1.305839910005313 1.3122212658700823 1.4280135524424413 1.3857142404724654 1.0 13.518738787520642 -6.96294710783256 24.99966027687495 1.3159955675451551 1.2200378809989658 0.03554015041856884 0.16843044382961014 512.763105013982 345960.8018036298 0.05996339062271027 0.05288260731492525 1.0890627208077228e-07 6.96294710783256 -0.0959576865461893 ETS(ph)SLESFVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETSSLESFVR 10 0 A0A087X2H1;Q9ULT8;H0YJP0 A0A087X2H1 HECTD1 E3 ubiquitin-protein ligase HECTD1 1 ET(0.002)S(0.498)S(0.498)LES(0.002)FVR 114.89 0.0024302 0.0 6592.3 9085.4 10231.0 11539.0 13918.0 9563.6 11790.0 10498.0 8048.1 8869.9 True False 7708.2461861399925 9987.338468683176 10474.945841283561 10892.507239942746 11190.867811198983 9062.067980244396 10673.165847791868 10222.438623550428 8165.788236990679 10477.94265591023 0.7356640935414976 0.9531774315494729 0.9997139882584699 1.039565456468563 1.0680405666170179 0.8648709272266163 1.0186318248049888 0.9756150571967789 0.7793312585447919 1.0 13.355067851053454 -4.763047232782955 4.764107855825805 0.9719018453849599 0.7187703401550115 0.42092057185300724 0.08131756515755284 0.18154713749031695 9.974174292539205 0.02038384237752513 0.15572484360381506 1.725650204378733e-05 4.763047232782955 -0.25313150522994843 ETSAATLSPGASS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 ETSAATLSPGASSR 14 0 A0A087WTU3;Q9Y6I9 A0A087WTU3 TEX264 Testis-expressed sequence 264 protein 1 ETSAATLSPGAS(0.045)S(0.954)R 101.45 0.0017059000000000002 5645900.0 16929.0 18909.0 25176.0 23613.0 23274.0 21400.0 22244.0 29964.0 23754.0 18677.0 True False 22312.069854925263 25020.964464351295 24842.14979029383 18169.38766721332 20042.806838483077 20061.854617024284 24223.672907662138 25333.752304220856 25009.587945247877 18023.123914836357 1.237969064650236 1.3882701235691124 1.3783487206590284 1.008115338554409 1.1120606468218392 1.1131174990429753 1.3440329779745666 1.4056249307239408 1.387638905631691 1.0 14.137561472045931 -7.288573582745986 24.423161652353507 1.3181262931277002 1.209110844452551 0.04077575228395869 0.1532868166794891 1476.2311031724219 1328730.431050261 0.06731024139207596 0.04539651080355141 5.145486193804566e-08 7.288573582745986 -0.10901544867514934 ETSFGS(ph)SENITMTSLSK ddPTM_PC-9_AZD4547_30min_R2 5 ETSFGSSENITMTSLSK 17 0 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9;A0A087WZS7 Q9UMZ2-4 SYNRG Synergin gamma 1 ETSFGS(0.993)S(0.007)ENITMTSLSK;ETSFGS(0.913)S(0.087)ENITMTSLSK;ET(0.015)S(0.067)FGS(0.699)S(0.214)ENIT(0.005)MT(0.001)SLSK;ETSFGS(0.807)S(0.125)ENIT(0.067)MT(0.001)SLSK;ETSFGS(0.946)S(0.053)ENITMTSLSK 235.75 2.5245999999999996e-37 73824700.0 208620.4 229665.3 316816.5 475824.9 424877.3 377141.6 333407.9 415827.2 338352.3 365466.2 True False 274957.3476261125 303900.11687527545 312615.3062057766 366130.82072642195 365890.420811043 353558.87613233365 363080.55720331415 351570.66099845496 356236.9118180892 352671.3395772541 0.7796418840150235 0.861709140412599 0.8864210700549341 1.0381643746988392 1.0374827204547854 1.0025166109504204 1.0295153488756346 0.9968790245895272 1.010110184301081 1.0 18.427964811953636 -5.525930910808058 2.175812210679498 1.0176082700053013 0.8140376594405723 0.9120317433629705 0.02510532370846278 0.08264199426183269 0.7701969456290939 0.007198636788757289 0.017748512983902204 2.9789903006643234e-06 5.525930910808058 -0.20357061056472903 ETSFGS(ph)SENITMTSLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETSFGSSENITMTSLSK 17 0 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9;A0A087WZS7 Q9UMZ2-4 SYNRG Synergin gamma 1 ETSFGS(0.948)S(0.05)ENIT(0.001)MTSLSK 152.25 3.1902e-05 26387000.0 191470.0 216860.0 274920.0 294340.0 360520.0 297290.0 306540.0 286790.0 278940.0 225390.0 True False 223882.08929512097 238388.42762218905 281475.1354399062 277849.0840631555 289878.6940144751 281699.5890508657 277502.312042589 279262.0663791226 283018.96979736513 266251.42281374196 0.8408672033716764 0.895350812036619 1.0571779578312868 1.043559058302298 1.0887404504773737 1.0580209715834292 1.0422566351381255 1.0488660057771122 1.0629763657464208 1.0 18.022429709374705 -5.173828596273031 3.2784454937967693 1.0538689809463686 0.8494182398946479 0.9173016495026989 0.02207448587075691 0.05882264515483329 1.1916313017971403 0.005601521972663487 0.01835401933151512 6.701490460711508e-06 5.173828596273031 -0.20445074105172067 ETSFGS(ph)SENITMTSLSK ddPTM_PC-9_Lapatinib_30min_R1 6 ETSFGSSENITMTSLSK 17 0 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9;A0A087WZS7 Q9UMZ2-4 SYNRG Synergin gamma 1 ET(0.019)S(0.017)FGS(0.798)S(0.158)ENIT(0.007)MT(0.001)SLSK;ETSFGS(0.774)S(0.226)ENITMTSLSK;ETSFGS(0.997)S(0.003)ENITMTSLSK;ETSFGS(0.961)S(0.039)ENITMTSLSK;ETS(0.002)FGS(0.911)S(0.086)ENIT(0.001)MTSLSK;ETS(0.002)FGS(0.864)S(0.058)ENIT(0.035)MT(0.035)S(0.005)LSK 284.46 9.160299999999997e-97 57650500.0 318451.9 270468.1 306321.0 247810.3 295820.3 263492.3 244204.3 277567.4 298499.1 206648.2 True False 313910.7175090743 269841.8477319606 281136.4698132545 266035.09613292647 278420.7315590869 252223.34855955112 256848.00375318344 290464.1947136117 264878.9880231265 242367.06602858144 1.2951871830311137 1.113360210830539 1.1599615179568215 1.0976536560522374 1.1487564549147686 1.0406667568018806 1.0597479598275712 1.1984474601815673 1.0928835850655152 1.0 17.886834146410685 -1.8670515163578822 1.1379980370189062 1.1010527221900623 199.9999998260655 0.518957499958785 0.055860254737924026 1362.5181962738936 2.2729347862565685 0.016543452429150774 706816.2071067005 0.013581523319185508 1.8670515163578822 198.89894710387543 ETSFGSS(ph)ENITMTSLSK ddPTM_PC-9_Lapatinib_30min_R1 1 ETSFGSSENITMTSLSK 17 0 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9;A0A087WZS7 Q9UMZ2-4 SYNRG Synergin gamma 1 ETS(0.001)FGS(0.146)S(0.851)ENIT(0.002)MTSLSK 102.72 0.00082415 31404000.0 492070.0 423380.0 468110.0 413120.0 444370.0 414860.0 376890.0 397440.0 452960.0 323270.0 True False 485052.9915654135 422399.68962239026 429623.8027568548 443502.22292792087 418233.0302650343 397117.40488589404 396403.5200630666 415906.51332605263 401942.87491974165 379146.78876980103 1.2793277061352442 1.114079565312764 1.133133170271161 1.1697375160869243 1.1030899974705166 1.0473975163403109 1.0455146444712289 1.0969538069293006 1.0601246979406207 1.0 18.532396978323206 -1.5228787452803376 0.24926166473324554 1.0263032738342617 2.329290594898403 0.7358337897413134 0.03826192467592808 28.711177220452925 0.38992365969646015 0.05139813080970434 15.669155794657799 0.029999999999999995 1.5228787452803376 1.3029873210641412 ETSFGSSENIT(ph)MTSLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETSFGSSENITMTSLSK 17 0 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9;A0A087WZS7 Q9UMZ2-4 SYNRG Synergin gamma 1 ET(0.001)S(0.005)FGS(0.037)S(0.006)ENIT(0.935)MT(0.015)S(0.002)LSK 96.993 0.005721199999999999 25607000.0 261940.0 317450.0 392800.0 428630.0 507710.0 460420.0 461140.0 450900.0 462730.0 369190.0 True False 306281.2684491762 348964.33804603794 402165.841702296 404615.25073720864 408227.870126731 436274.76467691275 417457.4808355158 439064.3527680417 469496.5508508458 436121.2244935671 0.7022847117904806 0.8001544489178726 0.9221423290492208 0.9277586781222495 0.936042199277904 1.0003520584982397 0.9572051470787187 1.006748417892049 1.076527636085666 1.0 18.734369677483038 -3.7339519681332973 0.4580540182494202 1.0175038768937554 1.4005342590199e-12 0.9151088717779217 0.030093812546997434 3.328494669511055 0.25861194846248037 0.020131433377888124 2.247939064047626 0.00018452194844833164 3.7339519681332973 -1.017503876892355 ETSHGS(ph)PTVTK ddPTM_PC-9_AZD4547_30min_R2 1 ETSHGSPTVTK 11 0 Q8NI08-2;Q8NI08;Q8NI08-7 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 1 ET(0.014)S(0.001)HGS(0.943)PT(0.04)VT(0.001)K 118.87 0.0010214 3422800.0 9091.3 8833.3 11322.0 17310.0 15447.0 10703.0 10317.0 13981.0 8747.5 12633.0 True False 11982.14428921271 11688.491480403734 11171.862882336623 13319.446936834054 13302.45068462869 10033.73971803789 11235.193013322703 11820.557701418767 9209.874991624807 12190.722515185933 0.9828904131224875 0.9588021928842551 0.9164233595194936 1.0925888043339576 1.091194608691805 0.8230635801560492 0.9216183043562077 0.9696355311749527 0.7554822923868625 1.0 13.573496013152015 -6.766232418697671 24.999944337005687 0.8937908184302636 1.0051951372841923 0.3261969963506173 0.08215996914712909 157.27238485543992 820308.8249181578 0.0289586877246473 0.02636660591990238 1.7130403049488857e-07 6.766232418697671 0.11140431885392865 ETSHGS(ph)PTVTK ddPTM_PC-9_Lapatinib_30min_R1 2 ETSHGSPTVTK 11 0 Q8NI08-2;Q8NI08;Q8NI08-7 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 1 ET(0.002)S(0.025)HGS(0.973)PTVTK;ET(0.015)S(0.043)HGS(0.941)PT(0.001)VTK 148.41 7.2536e-05 5699600.0 32126.0 26036.0 34250.0 28491.0 30750.0 31318.0 25661.0 25345.0 28799.0 24454.0 True False 31667.877348813145 25975.71524164706 31434.09720882333 30586.323183189816 28941.345456826053 29978.60214582375 26989.601019762686 26522.62122647145 25555.35335308558 28680.841317093204 1.1041474341249442 0.9056817739222335 1.09599634338792 1.0664374466923667 1.0090828625580657 1.0452483528771908 0.9410324028283448 0.9247504608822092 0.8910252342512387 1.0 14.807799723888984 -7.293588702724876 6.117191343816256 0.9321566559397909 1.0344730963030149 0.40837057521427733 0.05781070871378157 0.19350749841759143 23.32430242439908 0.02342348946345586 0.016014761944355364 5.086409213787381e-08 7.293588702724876 0.10231644036322396 ETSPES(ph)SLIQDEIAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETSPESSLIQDEIAVK 16 0 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 ET(0.223)S(0.223)PES(0.277)S(0.277)LIQDEIAVK 63.29 0.019278 2312400.0 11264.0 10608.0 12709.0 13028.0 16354.0 15659.0 13328.0 13380.0 11661.0 11759.0 True False 13170.772725859073 11661.09213417034 13012.030759150894 12298.08339734589 13149.551098171292 14837.814473905966 12065.475353636133 13028.789177281838 11831.520064555394 13890.813615807218 0.9481642393409724 0.8394822979195733 0.9367364014116277 0.885339313987421 0.9466364938629371 1.0681746141220336 0.8685938554316273 0.9379428403283427 0.8517514086497838 1.0 13.761843483196586 -6.273122304005667 22.66597359243906 0.9447004561425459 0.9003846767573552 0.09907671953886388 0.06350185773984435 532.548476138488 1033190.0030027175 0.019708807948574207 0.022580172259114635 5.331847213248909e-07 6.273122304005667 -0.04431577938519071 ETSS(ph)DVALASHILTALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETSSDVALASHILTALR 17 0 O00273;O00273-2 O00273 DFFA DNA fragmentation factor subunit alpha 1 ET(0.33)S(0.168)S(0.501)DVALASHILTALR 85.969 0.007120399999999999 0.0 2069.2 1053.2 2516.2 2144.0 3379.9 2409.2 2713.8 1077.9 2048.9 1230.5 True False 2419.4746914371103 1157.7547356436842 2576.1957507416405 2023.8786309417842 2717.632857815163 2282.8573108457917 2456.729217789444 1049.6062671294553 2078.861286362021 1453.5799093673602 1.6644937618119222 0.796485097367349 1.7723110605339027 1.3923408117429432 1.8696136623117987 1.570506923034838 1.6901232618567792 0.7220836366583204 1.4301664964995293 1.0 10.505394669296958 -7.748174173908361 24.98406068664295 1.057093710175132 1.5257262201485107 0.3241010715697026 0.32118691375063146 266.7903617395224 502482.57383754797 0.14974273069110572 0.08580250476754278 1.7857712472237876e-08 7.748174173908361 0.4686325099733786 ETSS(ph)LESFVR ddPTM_PC-9_AZD4547_30min_R2 1 ETSSLESFVR 10 0 A0A087X2H1;Q9ULT8;H0YJP0 A0A087X2H1 HECTD1 E3 ubiquitin-protein ligase HECTD1 1 ET(0.013)S(0.104)S(0.851)LES(0.032)FVR 131.83 0.00016686 980960.0 5157.4 6154.2 9738.0 10200.0 11868.0 10929.0 9187.5 11978.0 8186.2 10743.0 True False 6797.345919415883 8143.424798059698 9608.867757303835 7848.547588429075 10220.333056591773 10245.60790231114 10005.169701454144 10127.075327057713 8618.905819541475 10366.89083991471 0.6556783537494841 0.7855223831146944 0.9268803834904554 0.7570782512930991 0.9858628989553302 0.9883009342457234 0.9651080401977551 0.9768671710197183 0.8313877277801436 1.0 13.339695656303446 -3.8999329205020397 0.5828320037016326 0.9547215782639686 4.3393775820523624e-17 0.6281357158645394 0.07015461594140183 6.307557343179397 0.7538108133758159 0.034339702724560564 5.102318423944559 0.00012591198757125796 3.8999329205020397 -0.9547215782639686 ETSS(ph)LESFVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETSSLESFVR 10 0 A0A087X2H1;Q9ULT8;H0YJP0 A0A087X2H1 HECTD1 E3 ubiquitin-protein ligase HECTD1 1 ET(0.007)S(0.287)S(0.621)LES(0.085)FVR 94.82 0.015898 0.0 7185.6 9240.9 8915.0 10486.0 16284.0 11406.0 9968.3 9332.9 11034.0 9502.2 True False 8401.980157930842 10158.275481019484 9127.567410325779 9898.503416070691 13093.267095672094 10807.849280884562 9024.030459757729 9087.921264024948 11195.351375722852 11224.873640626185 0.7485144534297077 0.9049790497644122 0.8131554708366938 0.881836511748786 1.1664511793062535 0.9628481911607195 0.8039315852159845 0.8096234804045397 0.9973699245222251 1.0 13.454411584064376 -4.357531900303153 0.905397290221895 0.9346396414375642 0.5240522637072005 0.2235847827185945 0.10495670557324074 7.789030181837996 2.9621448177886873 0.03908658290426097 3.7889776665112676 4.3900361825251255e-05 4.357531900303153 -0.4105873777303637 ETSS(ph)LESFVR ddPTM_PC-9_Lapatinib_30min_R1 1 ETSSLESFVR 10 0 A0A087X2H1;Q9ULT8;H0YJP0 A0A087X2H1 HECTD1 E3 ubiquitin-protein ligase HECTD1 1 ET(0.01)S(0.157)S(0.522)LES(0.311)FVR 82.494 0.014837000000000001 1023500.0 6392.1 8220.3 10383.0 5764.0 7472.6 7608.5 7043.4 6403.1 8459.2 5684.6 True False 6300.947481832427 8201.266400403723 9529.34981953905 6187.903788140335 7033.076359696859 7283.102191279776 7408.0727883791205 6700.611401665787 7506.4358166749425 6667.1755357466245 0.9450699847408194 1.2300960663825244 1.4292933744501906 0.9281147248881279 1.0548809345109373 1.092381946782533 1.1111261055990072 1.005014997091331 1.1258794337165046 1.0 12.70285999606042 -5.789372085071808 24.99999898973919 1.0506499853454345 1.2043480363131165 0.25462775110043 0.1221588495998351 292.87833130074256 262127.36264414564 0.03470332820993851 0.051485059841917855 1.6241566510311554e-06 5.789372085071808 0.15369805096768197 ETSTNGPVSQEAFSVTGPAAPGALPPPS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 ETSTNGPVSQEAFSVTGPAAPGALPPPSPK 30 0 Q86UK7-2;Q86UK7-3 Q86UK7-2 1 ETSTNGPVSQEAFSVT(0.001)GPAAPGALPPPS(0.999)PK 76.10600000000001 8.598899999999999e-05 0.0 10282.0 8609.3 10772.0 16847.0 13829.0 12884.0 11470.0 10321.0 10330.0 13448.0 True False 13551.462121114158 11392.087860962481 10629.156241700239 12963.184433555349 11909.082055915715 12078.361443258913 12490.80777966574 8726.126602985702 10876.022710887026 12977.18961325263 1.044252455653038 0.8778547744519812 0.8190645708717609 0.9989207848452041 0.9176934614374335 0.9307378410287068 0.9625202491385203 0.6724203670472968 0.838087678073237 1.0 13.663690361497933 ETTDTDTADQVIASFK ddPTM_PC-9_AZD4547_30min_R2 3 ETTDTDTADQVIASFK 16 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ;; 236.55 2.1430000000000004e-36 7988800.0 46045.8 42617.3 59429.4 78936.0 60289.8 58171.9 47045.6 58923.2 45107.3 57012.3 False True 60687.406587862126 56392.508798275914 58641.32732551989 60738.52474904284 51919.60194770032 54534.401897012845 51232.567260596516 49817.97336043476 47491.57978962195 55016.31673019355 1.1030801441230658 1.0250142530411728 1.065889736186881 1.1040092895878812 0.9437127934667114 0.9912405107825726 0.9312249584400027 0.9055126973466422 0.8632271771759316 1.0 15.747571935907368 -6.555943038367095 1.3656312595116367 0.9206368947027939 1.0717580180574866 0.6618313461765812 0.045630146153854266 0.24977333672859717 0.9650453555572482 0.019366335871371525 0.02097211109639282 2.780077876100985e-07 6.555943038367095 0.15112112335469274 ETTDTDTADQVIASFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ETTDTDTADQVIASFK 16 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ; 134.68 1.8636e-05 4793200.0 27281.0 32320.0 35120.0 32297.0 38415.0 33191.0 36601.0 36334.0 27833.0 27154.0 False True 31899.134475689076 35528.51600456122 35957.39399334168 30487.503798286776 30887.856514384897 31450.405530583866 33133.88831170736 35380.27099905521 28240.004970137245 32076.80524905427 0.9944610826425605 1.1076076850143521 1.120978031139863 0.9504532499908372 0.9629343157637426 0.9804718794902784 1.0329547489048727 1.1029861211037635 0.8803870819077237 1.0 14.969242840517397 -5.762120125588962 24.999968813583962 0.9920795523443067 1.0776748081558407 0.28819482231601967 0.06238718474984892 24.00988493981072 881814.6510927418 0.017449276322991807 0.027719186378635158 1.729337959230208e-06 5.762120125588962 0.08559525581153404 ETTDTDTADQVIASFK ddPTM_PC-9_Lapatinib_30min_R1 4 ETTDTDTADQVIASFK 16 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ;;; 286.74 6.234999999999999e-96 47168900.0 128233.0 134276.0 153935.0 137561.0 144378.0 130836.0 130599.0 120504.0 132478.0 135640.0 False True 126404.37390494785 133965.09217189276 141279.05850628365 147677.69483004377 135885.96989806934 125240.44927361232 137360.7771941852 126103.0557614804 117556.93258481432 159085.19327106047 0.7945703261621039 0.8420965485055147 0.8880717029746603 0.9282931478005008 0.8541710708836197 0.7872539656171451 0.8634416212459215 0.7926762583530775 0.738955839746271 1.0 17.279440038650783 -6.537857421631777 24.150367437114458 0.8246958740994261 0.8669829811570912 0.016566978890294348 0.07216500061224733 465.7226401466095 750884.6465823936 0.023185392596278782 0.02319468878647458 2.898294938352626e-07 6.537857421631777 0.04228710705766503 ETTEES(ph)IK ddPTM_PC-9_AZD4547_30min_R2 1 ETTEESIK 8 0 Q5SZC6;Q9Y2T3-3;Q9Y2T3-2;Q9Y2T3 Q5SZC6 GDA Guanine deaminase 1 ETTEES(1)IK 81.191 0.015734 600840.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ETTGSES(ph)DGGDSSSTK ddPTM_PC-9_AZD4547_30min_R2 2 ETTGSESDGGDSSSTK 16 0 Q5JPT2;Q96B97-2;Q96B97;Q5VSN0;Q5JPT1;Q5JPT3 Q5JPT2 SH3KBP1 SH3 domain-containing kinase-binding protein 1 1 ET(0.466)T(0.002)GS(0.024)ES(0.507)DGGDSSSTK;ET(0.002)T(0.03)GS(0.039)ES(0.863)DGGDS(0.056)S(0.004)S(0.001)T(0.005)K 241.66 7.714199999999999e-38 11659700.0 26041.0 21086.3 28060.0 28404.0 23736.0 29478.0 27995.0 25695.0 29410.0 23558.0 True False 34321.496313551215 27902.034109929165 27687.906065921718 21855.896637425427 20440.666113183546 27634.736000030003 30486.500766498903 21724.428162359996 30964.552558295014 22733.241590497124 1.5097493323564632 1.2273671574225773 1.2179479972401175 0.9614069577548306 0.899153164400808 1.2156091285979114 1.3410538327821568 0.9556238636658474 1.3620825888393635 1.0 14.472515795913434 -4.672289050198878 1.6102147685512185 1.1136722912867105 1.7316175028098353 0.37120951796573576 0.15477435620382146 1.5291670113771891 3.124309559289549 0.0438955446199279 1.614968641642532 2.1267231073080854e-05 4.672289050198878 0.6179452115231248 ETTGSES(ph)DGGDSSSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ETTGSESDGGDSSSTK 16 0 Q5JPT2;Q96B97-2;Q96B97;Q5VSN0;Q5JPT1;Q5JPT3 Q5JPT2 SH3KBP1 SH3 domain-containing kinase-binding protein 1 1 ETTGS(0.007)ES(0.993)DGGDSSSTK;ET(0.011)T(0.183)GS(0.287)ES(0.519)DGGDSSSTK 205.12 6.4351e-17 12013800.0 22581.7 27967.0 23031.0 24726.0 31147.0 26188.0 25485.0 20002.0 24261.0 22494.0 True False 26404.33580109481 30743.37893253601 23580.146385553893 23340.682382773597 25043.968940610346 24814.6551786608 23070.87630457809 19476.968693870826 24615.771227697314 26571.984137593987 0.9936907859183166 1.1569846938543193 0.8874063097227561 0.8783944120210146 0.9424952540588865 0.9338653466811716 0.868240632130194 0.7329888725288998 0.9263806232998225 1.0 14.697618337848045 -5.277864313953356 24.483917907325207 0.8880463745091207 1.0753377300990383 0.47154480074175953 0.07545085104672997 435.4822852048932 649154.1215836448 0.019765240181138347 0.041349063622250916 5.273946088809053e-06 5.277864313953356 0.1872913555899176 ETTGSES(ph)DGGDSSSTK ddPTM_PC-9_Lapatinib_30min_R1 2 ETTGSESDGGDSSSTK 16 0 Q5JPT2;Q96B97-2;Q96B97;Q5VSN0;Q5JPT1;Q5JPT3 Q5JPT2 SH3KBP1 SH3 domain-containing kinase-binding protein 1 1 ET(0.246)T(0.124)GS(0.183)ES(0.447)DGGDSSSTK;ETTGS(0.001)ES(0.999)DGGDSSSTK 195.38 8.3823e-12 13012500.0 24099.3 53213.0 46153.0 45305.4 50724.0 42269.0 49486.6 56914.0 53797.0 50700.0 True False 23755.63956272963 53089.78856789697 42358.47849573203 48637.31025038395 47740.51404722094 40461.253403851566 52048.77400820653 59558.43221477203 47737.8153524756 59463.42744649647 0.3995000050090333 0.8928141354728615 0.7123450550146139 0.8179365424932231 0.8028550673466732 0.6804393076779416 0.8753073316373927 1.0015977008449612 0.8028096832364524 1.0 15.859715001516058 -3.3394502408266415 0.21099877044356202 0.9769362426438739 2.3170393915928012e-23 0.45686465872324533 0.12279524234175235 25.31718886227239 0.610166128514913 0.2180397178855627 7.126405721859135 0.00045766716897515346 3.3394502408266415 -0.9769362426438739 ETTQNALQT(ph)PCYTPYYVAPEVLGPEK ddPTM_PC-9_AZD4547_30min_R2 2 ETTQNALQTPCYTPYYVAPEVLGPEK 26 0 C9J8E1;Q16644 C9J8E1 MAPKAPK3 MAP kinase-activated protein kinase 3 1 ETTQNALQT(0.832)PCY(0.066)T(0.101)PY(0.001)YVAPEVLGPEK;ETTQNALQT(0.981)PCY(0.009)T(0.01)PYYVAPEVLGPEK 103.18 2.8775e-09 8430200.0 37375.1 39274.0 53055.0 90246.0 62466.0 69212.0 87560.0 193635.0 145886.0 108086.0 True False 49259.604349625886 51968.55245507074 52351.45603447885 69441.17898680108 53793.67414164663 64884.16269876095 95352.67037380408 163713.16003964102 153597.23612782802 104301.94203881794 0.47227887982462485 0.4982510530410801 0.5019221599440139 0.6657707194076715 0.5157494969904424 0.6220801015825101 0.9141984176892581 1.5696079750721426 1.4726210569565799 1.0 16.67040649465008 -7.504664847799205 2.868687016282661 1.3881665668141945 0.5458245307784021 0.8435161693350172 0.15372394789923705 0.09110905381230748 1.5110790663850122 0.07684860623650006 0.043616632021810334 3.1284927451333113e-08 7.504664847799205 -0.8423420360357924 ETTQNALQTPCY(ph)TPYYVAPEVLGPEK ddPTM_PC-9_AZD4547_30min_R2 1 ETTQNALQTPCYTPYYVAPEVLGPEK 26 0 C9J8E1;Q16644 C9J8E1 MAPKAPK3 MAP kinase-activated protein kinase 3 1 ETTQNALQT(0.126)PCY(0.763)T(0.072)PY(0.029)Y(0.01)VAPEVLGPEK 84.214 0.00075217 0.0 12489.0 12456.0 16365.0 23377.0 14266.0 18189.0 25918.0 50315.0 41283.0 27950.0 True False 16460.242212662382 16482.158409644082 16147.98940729896 17987.79382104966 12285.41214908479 17051.63895462872 28224.651790181044 42539.972873677485 43465.135099085106 26971.479007317877 0.6102832628569017 0.6110958322000866 0.5987061148154946 0.6669190746332164 0.4554964207098737 0.6322100078383646 1.0464628870564776 1.577220621165624 1.6115221225833476 1.0 14.71914701487968 -7.461588514724118 2.8481666234616383 1.4413980415431649 0.5920511898414976 0.8233830053200648 0.16675997334604697 0.09811685428641587 1.567884469448235 0.0806508025420964 0.04733273167406819 3.4547091104828113e-08 7.461588514724118 -0.8493468517016672 ETTSGTSTEPVKNS(ph)SPAPPQPAPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETTSGTSTEPVKNSSPAPPQPAPGK 25 1 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 ETTSGTSTEPVKNS(0.5)S(0.5)PAPPQPAPGK 95.195 1.2658e-06 10019000.0 57811.0 41157.0 43164.0 67341.0 73891.0 65733.0 61909.0 58214.0 57943.0 47652.0 True False 67597.26048070294 45242.79496286282 44193.19346038156 63568.10209246763 59412.58898098178 62285.845763666905 56044.53133765451 56685.94418283147 58790.306757613645 56290.93038697556 1.2008552712844023 0.8037315185916872 0.7850855041224698 1.1292778722160868 1.0554558002958236 1.1064987793855763 0.9956227575627696 1.0070173612896494 1.0444010492179818 1.0 15.780614873084422 -5.775941134145063 24.99997170837871 1.0491423039314143 0.9172747887595204 0.18503436158994258 0.11296533697238627 346.73068065566594 597737.6151126078 0.031753145993548046 0.04733063065497896 1.6751699192675414e-06 5.775941134145063 -0.13186751517189388 ETTSGTSTEPVKNS(ph)SPAPPQPAPGK ddPTM_PC-9_Lapatinib_30min_R1 1 ETTSGTSTEPVKNSSPAPPQPAPGK 25 1 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 ETTSGTSTEPVKNS(0.5)S(0.5)PAPPQPAPGK 76.417 7.0022e-05 16176000.0 101000.0 94696.0 116590.0 100310.0 99835.0 104520.0 78659.0 79968.0 96668.0 77117.0 True False 99559.72147886823 94476.73723010502 107004.42025041464 107687.13202435068 93962.90158316198 100049.92324802029 82731.578138557 83683.60521753671 85780.23188083178 90446.57069805644 1.1007572836700996 1.0445585332969973 1.1830677429179082 1.19061597574384 1.0388774373419234 1.1061770775370061 0.9147011047521647 0.9252269552253454 0.9484077861525275 1.0 16.464778183327994 -7.254746907362032 24.10591079151149 0.9408528713616814 1.1113310055373735 0.7132229914465655 0.050756537178583964 178.38661152388545 642540.6517043825 0.020740328261831985 0.01567336086530925 5.5622831452893426e-08 7.254746907362032 0.17047813417569213 ETTSGTSTEPVKNSS(ph)PAPPQPAPGK ddPTM_PC-9_AZD4547_30min_R2 2 ETTSGTSTEPVKNSSPAPPQPAPGK 25 1 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 ETTSGTST(0.001)EPVKNS(0.147)S(0.852)PAPPQPAPGK;ETTSGTSTEPVKNS(0.338)S(0.662)PAPPQPAPGK 113.63 7.239899999999999e-09 32236000.0 88618.0 77901.0 123503.0 138919.0 143218.0 122131.0 96096.0 121172.0 106909.0 120206.0 True False 116796.68063109257 103080.97481291606 121865.26952457335 106893.37082715466 123334.65282262897 114494.12926316806 104648.35783738081 102447.651655555 112559.9914809508 115997.6245278591 1.0068885557483254 0.8886472911189587 1.050584182396813 0.9215134470403067 1.063251539198613 0.9870385684981855 0.9021594904492847 0.8831874969211132 0.9703646254748719 1.0 16.823735735677865 -7.2434527473689485 23.48211940578137 0.9291935310215762 0.9853530639612846 0.12908716628411598 0.05811488928506944 643.9276174808957 840668.1999528395 0.02142152678773806 0.01654931307633157 5.708831867126395e-08 7.2434527473689485 0.056159532939708434 ETTSGTSTEPVKNSS(ph)PAPPQPAPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETTSGTSTEPVKNSSPAPPQPAPGK 25 1 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 ETTSGTSTEPVKNS(0.336)S(0.663)PAPPQPAPGK 79.143 4.6587e-05 14210000.0 56903.0 38760.0 43594.0 65011.0 65248.0 71064.0 69284.0 53503.0 54496.0 48163.0 True False 66535.55401452056 42607.836644083945 44633.44629116567 61368.64443850579 52463.122786687076 67337.27873897784 62720.91794727825 52098.60294111439 55292.90090369701 56894.57064190179 1.1694534867535913 0.7488910833383471 0.7844939470954363 1.078637974522457 0.9221112347765741 1.1835448968022477 1.1024060334693073 0.9157042992560127 0.9718484607558462 1.0 15.796003364564038 -5.774172511194503 24.99883298075844 1.0269385527128312 0.8857406431269622 0.15688989694586764 0.13018750651802347 363.5765048707928 713805.7266110481 0.03695824341781757 0.055222165995172365 1.682005799144102e-06 5.774172511194503 -0.14119790958586897 ETTSGTSTEPVKNSS(ph)PAPPQPAPGK ddPTM_PC-9_Lapatinib_30min_R1 1 ETTSGTSTEPVKNSSPAPPQPAPGK 25 1 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 ETTSGTSTEPVKNS(0.158)S(0.842)PAPPQPAPGK 99.569 8.1093e-07 15883000.0 83625.0 67950.0 75543.0 76188.0 70688.0 71540.0 66140.0 67837.0 77830.0 54267.0 True False 82432.49216505318 67792.66594983547 69332.14614441273 81791.11967571756 66530.27081795514 68480.40096788527 69564.40557449455 70988.95467114396 69063.9658137661 63646.97864376778 1.2951516933180431 1.06513564971043 1.0893234466393895 1.2850746636930335 1.0453013204338442 1.0759411118502602 1.0929726289734287 1.1153546670057857 1.085109887152966 1.0 15.957804409793743 -1.5228787453493555 0.09800659813175253 0.9512360464168451 1.6427173439655844 0.3313087217033085 0.07561863550078357 182.51980355791704 1.2763877130327046 1.0546463031712685 16.959952544825914 0.02999999999523241 1.5228787453493555 0.6914812975487393 ETTSHNSLT(ph)TPCYTPYYVAPEVLGPEK ddPTM_PC-9_AZD4547_30min_R2 1 ETTSHNSLTTPCYTPYYVAPEVLGPEK 27 0 P49137-2;P49137 P49137-2 MAPKAPK2 MAP kinase-activated protein kinase 2 1 ET(0.002)T(0.002)S(0.002)HNS(0.006)LT(0.528)T(0.41)PCY(0.021)T(0.023)PY(0.005)Y(0.001)VAPEVLGPEK 74.206 0.00012575 4159300.0 3593.7 4931.9 39586.0 118640.0 53430.0 50412.0 30168.0 137370.0 50186.0 73073.0 True False 4736.4218463964135 6526.0402264389495 39061.06377496708 91289.38096972807 46012.166768933166 47259.729670720946 32852.8935568401 116142.6229485653 52838.72950325039 70514.73651169015 0.06716924831182196 0.09254860117582717 0.553941852544417 1.2946142251356756 0.6525184528102878 0.6702106823144136 0.46590110354299696 1.6470688070898603 0.7493288937481972 1.0 16.105637169977776 -5.4335809984939845 3.511896750328608 0.9132759995109163 0.08363098662571937 0.5154378433753257 0.32560688105206026 0.19540463227127294 4.4864044587211955 0.08997856842440155 0.2024241992975076 3.684843109361303e-06 5.4335809984939845 -0.829645012885197 ETTSHNSLTT(ph)PCYTPYYVAPEVLGPEK ddPTM_PC-9_AZD4547_30min_R2 1 ETTSHNSLTTPCYTPYYVAPEVLGPEK 27 0 P49137-2;P49137 P49137-2 MAPKAPK2 MAP kinase-activated protein kinase 2 1 ET(0.007)T(0.007)S(0.007)HNS(0.009)LT(0.128)T(0.46)PCY(0.174)T(0.091)PY(0.08)Y(0.038)VAPEVLGPEK 49.37 0.04621 6281000.0 1685.1 2327.2 16441.0 57986.0 26021.0 21492.0 11091.0 56336.0 20970.0 27370.0 True False 2220.9267477426033 3079.421889123609 16222.98159764143 44618.223574769436 22408.4333051546 20148.101842480653 12078.077513886028 47630.56567249322 22078.43138889652 26411.784630779624 0.08408847712450265 0.11659272298983268 0.6142326928842051 1.6893301304135462 0.8484255652698447 0.7628451512890411 0.45729880364882813 1.8033830859345175 0.8359310700711559 1.0 14.688894166514084 -5.46271183694907 4.218701710131713 1.0518095912131753 0.12453795008284137 0.48870286857483736 0.38966843204281004 0.18601681131409215 6.59545824522035 0.10644945041724067 0.2266660972302874 3.4457848962890283e-06 5.46271183694907 -0.9272716411303339 ETVDQVEELRR ddPTM_PC-9_AZD4547_30min_R2 2 ETVDQVEELRR 11 1 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2;A0A2R8Y5T0 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ; 151.79 0.00023527 12031900.0 34331.0 37545.0 56927.0 77533.0 51036.0 48161.0 50755.0 50527.0 45123.0 53738.0 False True 45247.54387083933 49680.68701750854 56172.110784559 59658.964722909004 43950.53234548519 45149.48505656575 55272.0966745366 42719.213144952875 47508.10965956973 51856.648976574186 0.8725504783635274 0.9580389014328979 1.0832190643466817 1.1504593123604931 0.8475389986217482 0.8706595190322007 1.0658632550573277 0.8237943250874334 0.9161430712777281 1.0 15.662241360498081 -6.28815129671247 24.983871620002365 0.9166157378141357 1.01671871637494 0.1924025220919794 0.09553220923767405 1268.278375146797 1186227.4816149608 0.0309266133941152 0.03507688298526328 5.150491838088423e-07 6.28815129671247 0.1001029785608043 ETVDQVEELRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ETVDQVEELRR 11 1 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2;A0A2R8Y5T0 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ; 116.74 0.00077917 7998500.0 37850.0 50384.0 39328.0 50225.0 47084.0 38152.0 43050.0 41875.0 39055.0 30018.0 False True 44257.257428423836 55385.79054374418 40265.72867227057 47411.05608164698 37858.22819532207 36151.241957242484 38971.99234499064 40775.82562023001 39626.10549019901 35460.02577764276 1.2480886986925896 1.5619218917394144 1.1355245177982292 1.337028246368034 1.0676311526877502 1.019492827893981 1.0990401583284282 1.1499096440572476 1.117486652115829 1.0 15.113905964552657 -5.901790344269453 1.2994995745960087 1.0812204538122518 1.3820159252719473 0.523138070639883 0.11110923839877508 0.34890539386999003 1.1927765540832045 0.03809500479202053 0.07959220886220927 1.2537462750882386e-06 5.901790344269453 0.30079547145969543 ETVDQVEELRR ddPTM_PC-9_Lapatinib_30min_R1 2 ETVDQVEELRR 11 1 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2;A0A2R8Y5T0 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ; 142.89 9.209299999999999e-05 8013400.0 42059.0 52827.0 57265.0 44095.0 50512.0 55722.0 46892.0 46100.0 59242.0 37929.0 False True 41459.23094732402 52704.6823271812 52556.8927492925 47337.89339660789 47540.98347041295 53338.89995432625 49319.83831568184 48241.97429632408 52569.542114083684 44484.977112784305 0.9319827419987424 1.1847748554204534 1.181452619747183 1.0641321288440924 1.0686974919618515 1.1990317499567165 1.1086852577363262 1.0844554145552223 1.1817369711307775 1.0 15.44103058969341 -4.749694925986287 24.9993170614157 1.122667314631148 0.9319823168630944 0.4421303956129572 0.0629887689594381 492.25093573096785 1047743.4699398834 0.015178629104683003 0.24175628200191995 1.779529017042314e-05 4.749694925986287 -0.1906849977680537 ETVFTKS(ph)PYQEFTDHLVK ddPTM_PC-9_AZD4547_30min_R2 1 ETVFTKSPYQEFTDHLVK 18 1 H0YEN5;P15880;E9PQD7 H0YEN5 RPS2 40S ribosomal protein S2 1 ET(0.001)VFT(0.088)KS(0.807)PY(0.103)QEFTDHLVK 87.824 0.00067564 11286000.0 40676.0 27858.0 45490.0 79180.0 54409.0 46920.0 30277.0 46963.0 39608.0 48968.0 True False 53610.12188664069 36862.553707118204 44886.77287736202 60926.27431880524 46855.24951770326 43986.084982746695 32971.594345679136 39705.94745238033 41701.59801866538 47253.64522469922 1.1345182288417186 0.7800996839890428 0.949911327769904 1.289345489201739 0.9915689952573707 0.9308506205941423 0.6977576902034441 0.8402726871878712 0.8825054198542166 1.0 15.52813800506833 -6.914023093975424 3.6539535777652743 0.8389488335542209 1.0249912654305195 0.24947419312154462 0.14046393423298678 0.3329433508659236 8.718470672166177 0.0543981288712972 0.04703584446846855 1.2189247798480852e-07 6.914023093975424 0.18604243187629865 ETVFTKSPY(ph)QEFTDHLVK ddPTM_PC-9_AZD4547_30min_R2 1 ETVFTKSPYQEFTDHLVK 18 1 H0YEN5;P15880;E9PQD7 H0YEN5 RPS2 40S ribosomal protein S2 1 ETVFTKS(0.013)PY(0.986)QEFTDHLVK 91.932 0.0014727 11848000.0 36765.0 30852.0 43462.0 68180.0 58469.0 45730.0 31313.0 43757.0 38723.0 48984.0 True False 48455.50524049427 40824.305656257144 42885.66548243367 52462.154370499455 50351.58859840454 42870.49587086544 34099.796338681175 36995.361085829376 40769.818725428704 47269.0850695692 1.0250992835841637 0.8636576230780261 0.9072666716378338 1.1098618535410036 1.0652118297677775 0.9069457512826818 0.721397426848735 0.7826544776862241 0.862504926114498 1.0 15.52860932001564 -7.000792611279559 22.322233481037728 0.8221905642781971 0.9883118458984883 0.3612053119318991 0.09439921869012718 7.766700464584639 218759.5788986985 0.03485830409386681 0.030282002300703704 9.981766094831786e-08 7.000792611279559 0.16612128162029116 ETVNS(ph)PAIYK ddPTM_PC-9_AZD4547_30min_R2 2 ETVNSPAIYK 10 0 Q9Y3A2 Q9Y3A2 UTP11L Probable U3 small nucleolar RNA-associated protein 11 1 ET(0.19)VNS(0.81)PAIYK;ET(0.01)VNS(0.99)PAIYK 157.56 0.00027537 25619200.0 188017.0 239642.0 253536.0 327599.0 248375.0 210669.0 202589.0 234573.0 197516.0 244632.0 True False 247802.49500345465 317101.5900452736 250173.94698252028 252076.1119040959 213892.4185145758 197495.8341268176 220619.02853310385 198325.1328012949 207956.2925230939 236067.50814018515 1.049710300903845 1.3432665619402717 1.059755952665702 1.0678136685985784 0.9060646261727768 0.8366074420099257 0.934559060123143 0.8401204145532917 0.8809187429538257 1.0 17.84883996000665 -5.960814095804995 1.6229728413926565 0.8875538269524973 1.1884363412144343 0.6433884902842169 0.08599216454889365 0.20708788868159445 1.105070563760521 0.027153329737353203 0.047795047984471005 1.0944247457239747e-06 5.960814095804995 0.300882514261937 ETVNS(ph)PAIYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ETVNSPAIYK 10 0 Q9Y3A2 Q9Y3A2 UTP11L Probable U3 small nucleolar RNA-associated protein 11 1 ET(0.106)VNS(0.894)PAIYK;ET(0.023)VNS(0.977)PAIYK;ET(0.032)VNS(0.968)PAIYK 165.35 0.00032439999999999997 29236700.0 226105.0 210699.0 218619.0 249779.0 280119.0 226901.0 244950.0 285308.0 221923.0 156847.0 True False 264380.1107226887 231615.80425881923 223831.7060771744 235784.69242444364 225231.69280106685 215001.91212361815 221746.56271557405 277818.96730881435 225168.20403793236 185282.11949983082 1.4269056908264164 1.2500709992095633 1.2080588600854103 1.2725712176703534 1.2156148332557934 1.1604029180150568 1.1968049767251099 1.4994375499308126 1.215272173298611 1.0 17.49936413640858 -4.763151905115592 5.072314808963314 1.2369457246664122 1.438340812562963 0.20838418333366338 0.11642455724746528 0.2866366406468081 19.954552389002338 0.02852793006187243 0.20549795142271504 1.7252343435416804e-05 4.763151905115592 0.20139508789655092 ETVNS(ph)PAIYK ddPTM_PC-9_Lapatinib_30min_R1 2 ETVNSPAIYK 10 0 Q9Y3A2 Q9Y3A2 UTP11L Probable U3 small nucleolar RNA-associated protein 11 1 ET(0.293)VNS(0.707)PAIYK;ET(0.08)VNS(0.92)PAIYK 110.93 0.0016683 21909800.0 132214.0 136147.0 139853.0 106323.0 103007.0 103616.0 108183.0 102207.0 107016.0 80656.0 True False 130328.60411492172 135831.7599863466 128354.82618819198 114142.34810313045 96948.33077955391 99184.58522069333 113784.18639651575 106955.91034499777 94962.7311515611 94597.2821326353 1.3777203866405734 1.4358949530483998 1.3568553270719244 1.2066133987136218 1.0248532367306515 1.0484929691915055 1.202827225384535 1.1306446436276507 1.003863208442008 1.0 16.529511113747354 -5.871695818057357 2.515953382180412 1.0812176628315324 1.4045024257207706 0.8471821431275207 0.061100129010102575 0.10811434014412696 1.3892176280216149 0.01922026326611623 0.032126631835884455 1.343705769605823e-06 5.871695818057357 0.32328476288923813 ETVQTTEDQILK ddPTM_PC-9_Lapatinib_30min_R1 1 ETVQTTEDQILK 12 0 P18206;P18206-2 P18206 VCL Vinculin 0 179.6 1.4331e-25 0.0 13299.0 12315.0 14515.0 13316.0 12180.0 12272.0 16320.0 13167.0 14333.0 11386.0 False True 13109.353821262082 12286.485374131342 13321.632729520308 14295.30306087381 11463.596346801341 11747.155167429237 17164.969745626724 13778.786888496734 12718.666606818826 13354.054929108665 0.9816758947641295 0.9200565251045751 0.9975721082652069 1.0704840692030888 0.858435614325161 0.8796695258324295 1.2853751041723793 1.0318054674511077 0.952419821120786 1.0 13.70499025912914 ETVQTTQS(ph)PTPVEK ddPTM_PC-9_AZD4547_30min_R2 2 ETVQTTQSPTPVEK 14 0 A0A0A0MT33;Q9UPN6;Q9UPN6-2 A0A0A0MT33 SCAF8 Protein SCAF8 1 ETVQTT(0.003)QS(0.916)PT(0.081)PVEK;ETVQT(0.003)TQS(0.972)PT(0.024)PVEK 244.54 6.053899999999999e-35 47730000.0 199751.0 293160.0 259909.0 138267.0 177500.0 298142.0 267307.0 334060.0 280720.0 214455.0 True False 263267.6629210929 387918.2369437424 256462.43683847602 106391.67935385526 152857.18887302317 279499.13360882486 291096.80515772535 282438.7029351226 295558.2860987612 206946.99572502178 1.272150204446101 1.8744811229788707 1.2392662958936946 0.5141011058465514 0.738629658949629 1.3505831898144867 1.4066249386123806 1.364787644998768 1.4281835069086026 1.0 17.658901779375768 ETVQTTQS(ph)PTPVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETVQTTQSPTPVEK 14 0 A0A0A0MT33;Q9UPN6;Q9UPN6-2 A0A0A0MT33 SCAF8 Protein SCAF8 1 ETVQTT(0.006)QS(0.776)PT(0.218)PVEK 244.18 6.319399999999999e-35 19457000.0 76791.0 129220.0 98183.0 68444.0 79816.0 53466.0 90452.0 42812.0 52545.0 55928.0 True False 89790.19960861566 142048.10761477074 100524.05508110125 64609.30457844196 64176.627763950084 50662.14883848626 81883.73174422984 41688.23036306355 53313.37121962634 66067.30367419553 1.359071652922409 2.150051534042726 1.521540149070194 0.9779316089098542 0.9713825779909359 0.7668263425479223 1.2393987220672948 0.6309963937478816 0.8069554568555731 1.0 16.0116488464798 -5.695201035987588 3.2886567990210915 0.900447332204401 1.772169872919215 0.6957938779883088 0.23446671703556426 0.11951517869445048 2.591063397032556 0.06345174114915525 0.11501068100004849 2.0174322731232226e-06 5.695201035987588 0.871722540714814 ETVQTTQS(ph)PTPVEK ddPTM_PC-9_Lapatinib_30min_R1 1 ETVQTTQSPTPVEK 14 0 A0A0A0MT33;Q9UPN6;Q9UPN6-2 A0A0A0MT33 SCAF8 Protein SCAF8 1 ETVQTT(0.002)QS(0.997)PT(0.001)PVEK 276.34 1.1407999999999998e-69 24136000.0 82317.0 235890.0 210520.0 192340.0 258730.0 241910.0 267920.0 290640.0 202450.0 218970.0 True False 81143.14448491104 235343.81119803878 193211.8582307 206485.32522743035 243512.01008275154 231564.073219753 281791.58665737195 304144.1954334841 179647.94910698873 256818.67274081515 0.31595500287785455 0.9163812299409821 0.7523279213645496 0.8040121188377066 0.948186545331566 0.9016636942651384 1.09723947892901 1.1842760192925321 0.6995128009570077 1.0 17.970390576006096 -4.5425269901969045 0.7986845812468574 0.9740715228730029 2.2325310717480094e-35 0.5451445023729249 0.15528880421647173 2.9714122850209503 1.1219067986944087 0.05817928059146315 2.809513169128797 2.867299175356914e-05 4.5425269901969045 -0.9740715228730029 ETVQTTQSPT(ph)PVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETVQTTQSPTPVEK 14 0 A0A0A0MT33;Q9UPN6;Q9UPN6-2 A0A0A0MT33 SCAF8 Protein SCAF8 1 ETVQTT(0.013)QS(0.298)PT(0.689)PVEK 144.4 0.00042848 21078000.0 75174.0 138670.0 105540.0 86410.0 87956.0 51008.0 88134.0 37511.0 45338.0 51761.0 True False 87899.47344582104 152436.2411618966 108056.47386267882 81568.72784499984 70721.653197429 48333.05068554795 79785.30948509646 36526.37599618979 46000.98247893082 61144.85956014945 1.4375611307006524 2.4930344473510804 1.7672209019693872 1.334024289723963 1.1566246730497214 0.7904679319444954 1.3048571876530357 0.5973744360351019 0.7523278785795346 1.0 15.899943596228418 -5.969301668387458 1.5888120565977886 0.8994855124352775 2.0012016125458567 0.674913722227316 0.30235355773760797 0.21025205653393836 1.0748119225490043 0.0999635318199606 0.1759417172286651 1.0732436599320433e-06 5.969301668387458 1.101716100110579 ETVQTTQSPT(ph)PVEK ddPTM_PC-9_Lapatinib_30min_R1 1 ETVQTTQSPTPVEK 14 0 A0A0A0MT33;Q9UPN6;Q9UPN6-2 A0A0A0MT33 SCAF8 Protein SCAF8 1 ETVQT(0.001)T(0.003)QS(0.113)PT(0.883)PVEK 224.06 5.9057e-20 24285000.0 37342.0 100560.0 80500.0 77870.0 111500.0 97465.0 110900.0 111130.0 89307.0 92932.0 True False 36809.49623231588 100327.15949838783 73881.60073898605 83596.81956670499 104941.7892174343 93296.64915201192 116641.85936213266 116293.50550001094 79248.3052155982 108995.17237589347 0.3377167578153862 0.9204734238355795 0.6778428725649366 0.7669772682995835 0.9628113514561892 0.855970472070618 1.0701561988439996 1.0669601502986534 0.7270808742087517 1.0 16.733904710873894 -4.4271558585211865 0.6127544792003052 0.9551014799329722 3.3561183424155166e-16 0.5333880094883285 0.14467054242357197 4.46835245151879 0.9317415364183952 0.06836941064443101 3.3081553242389026 3.739763524851478e-05 4.4271558585211865 -0.9551014799329719 ETVS(ph)PPCFDEYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ETVSPPCFDEYK 12 0 Q13029-5;Q13029-3;Q13029-2;Q13029 Q13029-5 PRDM2 PR domain zinc finger protein 2 1 ETVS(1)PPCFDEYK;ET(0.138)VS(0.862)PPCFDEYK 134.21 0.00041236 0.0 22680.0 21266.7 22914.1 21993.0 34826.0 22423.0 22622.0 16867.8 22209.7 18710.8 True False 26519.276049581324 23377.917429276058 23460.459046208158 20760.80351226803 28002.095300532812 21247.0984065645 20479.080390903102 16425.038122911417 22534.474845875644 22102.919925388687 1.1998087193502318 1.0576845732686584 1.061418994657811 0.9392787732276483 1.266895749297268 0.9612801601909102 0.9265328047168849 0.7431162117202746 1.0195247922873416 1.0 14.43194935023465 -6.98455527652465 24.964077964927768 0.9070321598008607 1.0930909700336575 0.39593834319732146 0.10773022928551439 231.88769867963688 374810.2131164792 0.037099183835754786 0.032708439987163336 1.0362027092947595e-07 6.98455527652465 0.1860588102327968 ETVS(ph)PPCFDEYK ddPTM_PC-9_Lapatinib_30min_R1 1 ETVSPPCFDEYK 12 0 Q13029-5;Q13029-3;Q13029-2;Q13029 Q13029-5 PRDM2 PR domain zinc finger protein 2 1 ET(0.468)VS(0.532)PPCFDEYK 112.5 0.0019222999999999998 0.0 14464.0 20913.0 26417.0 18605.0 15889.0 24217.0 21915.0 20140.0 26094.0 16792.0 True False 14257.740707627258 20864.57723339088 24245.09623256892 19973.2737644606 14954.440258975907 23181.295362584242 23049.65146908147 21075.777924684764 23155.018937998382 19694.474826066453 0.7239462252000012 1.0594127245157992 1.2310608151114308 1.014156200703821 0.7593216062396894 1.177045621541674 1.170361315681 1.0701365794628908 1.1757114186843793 1.0 14.265503326030148 ETVSEAPPLLFS(ph)DEEEKEAQLGVK ddPTM_PC-9_AZD4547_30min_R2 8 ETVSEAPPLLFSDEEEKEAQLGVK 24 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 ETVS(0.001)EAPPLLFS(0.999)DEEEKEAQLGVK;ETVS(0.003)EAPPLLFS(0.997)DEEEKEAQLGVK;ETVS(0.002)EAPPLLFS(0.998)DEEEKEAQLGVK;ETVS(0.007)EAPPLLFS(0.993)DEEEKEAQLGVK;ETVS(0.004)EAPPLLFS(0.996)DEEEKEAQLGVK;ETVS(0.001)EAPPLLFS(0.998)DEEEKEAQLGVK;ETVS(0.001)EAPPLLFS(0.999)DEEEKEAQLGVK;ETVSEAPPLLFS(1)DEEEKEAQLGVK 92.56299999999999 4.2926e-06 22447300.0 71098.50000000001 77013.1 74131.0 92891.59999999999 86849.4 88034.5 92843.0 97956.6 79558.70000000001 93304.20000000001 True False 93706.34405933022 101906.07850174698 73147.97450366503 71476.87678091355 74791.85993976744 82529.68879824431 101105.84713927674 82819.65828873467 83764.01045969487 90037.64835758807 1.040746240807754 1.131816305297346 0.8124154266352556 0.793855438083415 0.8306731828748861 0.9166131091126948 1.1229285635907647 0.919833645141565 0.9303220595791529 1.0 16.458240755897812 -9.605161573405434 15.705268568251292 0.9999835603753728 0.9419337524736492 0.020453917409697042 0.11442197911391679 0.0 0.0 0.12132259806598525 0.02942505215296554 2.4822094609347173e-10 9.605161573405434 -0.05804980790172365 ETVSEAPPLLFS(ph)DEEEKEAQLGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ETVSEAPPLLFSDEEEKEAQLGVK 24 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 ETVS(0.001)EAPPLLFS(0.999)DEEEKEAQLGVK;ETVS(0.002)EAPPLLFS(0.998)DEEEKEAQLGVK;ETVS(0.001)EAPPLLFS(0.999)DEEEKEAQLGVK 88.571 0.00013996 6028200.0 26400.6 30541.0 23497.2 34065.1 30511.1 24402.1 30707.8 26088.2 24541.5 24299.300000000003 True False 30869.700144381673 33572.90864156264 24057.46236162724 32156.542887544296 24532.66898076397 23122.41091855806 27798.93487878058 25403.412392732742 24900.37300954346 28704.570736847025 1.0754280364400415 1.1696014878378342 0.838105630708685 1.1202586230027156 0.854660716081438 0.8055306289209423 0.9684497682836304 0.8849953767162 0.8674706630459986 1.0 14.808992860504299 -5.301883858113388 0.96398560992105 0.8995324520106384 1.1588473160857833 0.3435939648729206 0.09875979174644799 1.095625951107957 1.3805717719049257 0.03487321817774074 0.2496663200575851 4.990179202716501e-06 5.301883858113388 0.2593148640751449 ETVSEAPPLLFS(ph)DEEEKEAQLGVK ddPTM_PC-9_Lapatinib_30min_R1 5 ETVSEAPPLLFSDEEEKEAQLGVK 24 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 ET(0.003)VS(0.009)EAPPLLFS(0.988)DEEEKEAQLGVK;ETVS(0.001)EAPPLLFS(0.999)DEEEKEAQLGVK;ETVS(0.001)EAPPLLFS(0.999)DEEEKEAQLGVK;ETVS(0.002)EAPPLLFS(0.998)DEEEKEAQLGVK;ETVS(0.002)EAPPLLFS(0.997)DEEEKEAQLGVK 88.95100000000001 0.00013128 5564900.0 31406.199999999997 42651.8 38384.1 36931.4 44240.7 43573.4 46780.4 40950.1 42920.0 43646.6 True False 30958.34182880827 42553.04237761878 35228.30746491082 39647.45835553883 41638.54900656277 41709.86725655646 49202.46021374489 42852.79114168981 38085.89763236337 51190.85665456122 0.6047631130245954 0.8312625566078939 0.6881757752684902 0.77450273245244 0.8133981677146378 0.814791351080858 0.9611571954297592 0.8371180703394526 0.7439980520226327 1.0 15.643598528893905 -1.743534782633784 0.10576288650750144 1.048807117817943 7.817758347522005e-16 0.5196656639560907 0.07675639041645352 96.81817130715348 0.7574689703522479 0.8334924424946308 14.710108871577255 0.018049501729300706 1.743534782633784 -1.0488071178179421 ETVSEESNVLCLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETVSEESNVLCLSK 14 0 P13639 P13639 EEF2 Elongation factor 2 0 189.3 1.3685999999999999e-05 2562100.0 6423.5 6711.8 7077.5 7913.8 6611.7 5370.1 7326.9 7914.1 6987.1 5982.9 False True 7510.871680091958 7378.103147259096 7246.254441568217 7470.415442885773 5316.1848474855815 5088.482502479237 6632.842989837674 7706.363260682082 7089.273119205465 7067.552409389659 1.062725996925516 1.0439403516069936 1.0252848541938142 1.0570017751776253 0.7521960276407313 0.7199780359207367 0.9384922255441009 1.0903864328538584 1.0030733001409298 1.0 12.786994961054047 ETVSEESNVLCLSK ddPTM_PC-9_Lapatinib_30min_R1 4 ETVSEESNVLCLSK 14 0 P13639 P13639 EEF2 Elongation factor 2 0 ;;; 205.87 4.1787e-10 37509800.0 93920.0 101840.0 99205.0 104171.0 97953.0 92246.0 102993.0 87880.0 97922.0 86239.0 False True 92580.68357718158 101604.19573703087 91048.7478423742 111832.08284426926 92191.59712300758 88300.85361592878 108325.47359138077 91963.22562171266 86892.99319562638 101145.29624375557 0.9153236681819226 1.0045370324702927 0.9001777761661882 1.10565777151672 0.9114768609785869 0.8730099855867517 1.0709887420797235 0.9092190051041569 0.8590907973240615 1.0 16.62606970344227 ETVVEVPQVTWEDIGGLEDVKR ddPTM_PC-9_Lapatinib_30min_R1 2 ETVVEVPQVTWEDIGGLEDVKR 22 1 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 ; 169.43 3.7929e-09 7330100.0 41533.0 35090.0 41382.0 35768.0 38844.0 34200.0 37994.0 35170.0 39955.0 37521.0 False True 40940.731803780596 35008.75126092318 37979.73169913945 38398.49803855019 36559.2722902423 32737.34572409387 39961.143413930215 36804.12659439738 35454.847155197545 44006.45485641014 0.9303346960660026 0.7955367314898276 0.8630491100240759 0.8725651308164153 0.8307706769275676 0.7439214504079786 0.9080745891556253 0.8363347312226482 0.8056737874224164 1.0 15.425427532988694 -10.614051446147418 4.623009186972309 1.000007651974982 0.8414422097236527 0.4527927994020685 0.051782431282045654 71164436.53103122 42443111.92589584 8183.819707509704 0.012488547345685629 2.431915909362081e-11 10.614051446147418 -0.1585654422513294 ETYEVEASTFCFPESVDVGGAS(ph)PHSK ddPTM_PC-9_AZD4547_30min_R2 1 ETYEVEASTFCFPESVDVGGASPHSK 26 0 A0A0A0MT72;Q9BSQ5-4;Q9BSQ5;Q9BSQ5-2;C9JUH3;Q9BSQ5-3 A0A0A0MT72 CCM2 Cerebral cavernous malformations 2 protein 1 ETYEVEASTFCFPES(0.018)VDVGGAS(0.83)PHS(0.152)K 89.35600000000001 3.9068000000000005e-07 4792700.0 14065.0 14030.0 19210.0 14723.0 15156.0 19771.0 17386.0 14641.0 15119.0 10469.0 True False 18537.377429825956 18564.923128396473 18955.262848408966 11328.839818082482 13051.851011603057 18534.716244541443 18933.32031885515 12378.569866709971 15918.159473949758 10102.4834965156 1.8349327109734546 1.8376593374094214 1.8762973337146984 1.121391568913709 1.2919447991283242 1.8346692920541927 1.8741253401092266 1.22529968705016 1.5756679512953438 1.0 13.302422374276508 -11.971438189058325 0.11072926724152198 1.499241671582713e-18 2.0078836689682253 0.3507961669635983 0.2690838849766571 105.4024655645669 1.4457297956636748 31.907073166324913 4.4290171237072435 1.0679767814680366e-12 11.971438189058325 2.0078836689682253 ETYVEQEQGENANDRNDR ddPTM_PC-9_Lapatinib_30min_R1 1 ETYVEQEQGENANDRNDR 18 1 F2Z2C0;Q9Y2L1 F2Z2C0 DIS3 Exosome complex exonuclease RRP44 0 77.191 0.037913 0.0 8428.2 7289.6 8788.9 5164.6 6411.4 8446.7 5248.2 6059.9 7140.9 4469.5 False True 8308.012322457409 7272.721379071689 8066.310568135102 5544.421912600545 6034.294057297382 8085.454331219408 5519.926116360181 6341.46507675259 6336.616644989371 5242.0471197656 1.5848793672859822 1.3873819164366632 1.5387710914921706 1.057682578184926 1.151133120216441 1.5424230546750508 1.053009633497344 1.209730651378836 1.208805739478495 1.0 12.35591460649832 -1.5228787452803376 0.22886616150887637 1.0832467811864488 3.742114883462967 0.44610225007195936 0.15714553927018893 51.20111788998164 0.6684863471329017 0.23443189039851908 50.91593011104364 0.029999999999999995 1.5228787452803376 2.6588681022765184 ETYYLS(ph)DSPLLGPPVGEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ETYYLSDSPLLGPPVGEPR 19 0 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 ETYYLS(0.583)DS(0.417)PLLGPPVGEPR 116.04 7.0133e-05 1455700.0 3088.5 1449.4 3701.2 3781.6 3597.7 1606.9 4726.8 1829.6 2867.5 1734.4 True False 3611.3220493444396 1593.2868532491036 3789.450644879165 3569.7292121126156 2892.756511305543 1522.6313352142217 4279.043284931516 1781.5749386214395 2909.4317627229734 2048.8329904971542 1.7626239259590133 0.7776557975389145 1.849565417218143 1.7423231804005714 1.4119044962291478 0.743170059383294 2.088527129726272 0.8695559603367847 1.4200433984699714 1.0 11.000586673305307 -6.531544951570743 24.93022230977208 1.2487248984245922 1.5111221889876196 0.09623904067232902 0.4432900245219221 551.8998796206844 1587646.7476929799 0.14223079710022637 0.14244509836422115 2.940729298347394e-07 6.531544951570743 0.2623972905630274 EVAATEEDVTRLPS(ph)PT(ph)SPFSSLSQDQAATSK ddPTM_PC-9_Lapatinib_30min_R1 1 EVAATEEDVTRLPSPTSPFSSLSQDQAATSK 31 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 2 EVAAT(0.016)EEDVT(0.053)RLPS(0.565)PT(0.565)S(0.565)PFS(0.072)S(0.072)LS(0.072)QDQAAT(0.008)S(0.009)K 54.31100000000001 0.014888 0.0 3212.2 3626.7 4531.0 3481.2 4129.2 3470.0 3227.2 2182.5 4751.2 2842.9 True False 3166.3934389546657 3618.3025989737844 4158.478670165795 3737.2190609427707 3886.328574319548 3321.5961889650816 3394.2886251891255 2283.906917607969 4216.0698236459675 3334.2914770738626 0.9496450627446218 1.0851788524946735 1.2471851062688826 1.1208435395163812 1.1655635390731187 0.9961925080047525 1.0179939721910323 0.6849751838769358 1.2644574874857504 1.0 11.703164512006296 -6.865853978952128 5.342222861626306 0.9713390767857106 1.119562322892381 0.13591061722240405 0.14818210932067472 0.3649518663214845 15.926702296344134 0.05151576986364872 0.04551017245452968 1.3619025123762238e-07 6.865853978952128 0.14822324610667037 EVAATEEDVTRLPS(ph)PTSPFSSLSQDQAATSK ddPTM_PC-9_AZD4547_30min_R2 4 EVAATEEDVTRLPSPTSPFSSLSQDQAATSK 31 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 EVAATEEDVT(0.007)RLPS(0.821)PT(0.041)S(0.041)PFS(0.025)S(0.033)LS(0.016)QDQAAT(0.007)S(0.008)K;EVAATEEDVT(0.004)RLPS(0.255)PT(0.255)S(0.255)PFS(0.097)S(0.097)LS(0.037)QDQAAT(0.001)SK;EVAATEEDVT(0.001)RLPS(0.68)PT(0.225)S(0.076)PFS(0.007)S(0.007)LS(0.003)QDQAATS(0.001)K;EVAAT(0.001)EEDVT(0.003)RLPS(0.813)PT(0.056)S(0.056)PFS(0.022)S(0.027)LS(0.021)QDQAATSK 70.15100000000001 2.5266e-05 247375000.0 88953.0 90349.0 118166.0 177102.0 154137.0 143309.0 109146.0 156045.0 130600.0 135231.0 True False 117238.20366265954 119552.54737900868 116599.04163170712 136273.87009862406 132737.73814828842 134347.86557528676 118859.78255618108 131931.8308073738 137503.2493748158 130496.60385111267 0.8984004196493878 0.9161353157926595 0.8935024988446314 1.0442713915689548 1.017173889825767 1.0295123521265588 0.910826634935202 1.0109981939292354 1.053692167588493 1.0 16.99365273586099 -5.75220135545048 24.99969245598807 1.0069972909227984 0.9040249710776598 0.6343494853807468 0.03712553429699609 135.68520391968744 367184.01140139083 0.010621321247643216 0.01807455072703704 1.7692884586584874e-06 5.75220135545048 -0.10297231984513866 EVAATEEDVTRLPS(ph)PTSPFSSLSQDQAATSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 EVAATEEDVTRLPSPTSPFSSLSQDQAATSK 31 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 EVAATEEDVT(0.001)RLPS(0.611)PT(0.124)S(0.164)PFS(0.045)S(0.045)LS(0.01)QDQAAT(0.001)SK;EVAATEEDVT(0.011)RLPS(0.959)PT(0.011)S(0.011)PFS(0.003)S(0.003)LS(0.003)QDQAATSK;EVAAT(0.001)EEDVT(0.002)RLPS(0.413)PT(0.377)S(0.128)PFS(0.031)S(0.009)LS(0.04)QDQAATSK;EVAAT(0.001)EEDVT(0.003)RLPS(0.953)PT(0.037)S(0.004)PFS(0.002)S(0.001)LSQDQAATSK;EVAATEEDVT(0.004)RLPS(0.826)PT(0.1)S(0.042)PFS(0.01)S(0.014)LS(0.003)QDQAATSK 92.92399999999999 4.0061e-10 202927700.0 101194.7 89500.9 109572.7 135473.7 148306.0 128826.3 118463.0 115772.4 108941.2 103009.6 True False 118324.96402357021 98385.95786115807 112185.32872477853 127883.54780066118 119246.50392352902 122070.42204226018 107241.3270421516 112733.49717099733 110534.25895349827 121684.42505645497 0.9723920211536837 0.8085336953805905 0.9219366297102577 1.0509442579962895 0.9799652163225089 1.0031721149656263 0.8813069297274277 0.9264414662656713 0.9083681736772505 1.0 16.89278499719868 -5.523937096934714 24.99989493437345 0.962090812143023 0.8841559254970408 0.20170784337778858 0.059604171664601885 49.81003022114954 1176580.64198846 0.016516920990241494 0.028909735515359747 2.9926980665902457e-06 5.523937096934714 -0.07793488664598225 EVAATEEDVTRLPS(ph)PTSPFSSLSQDQAATSK ddPTM_PC-9_Lapatinib_30min_R1 3 EVAATEEDVTRLPSPTSPFSSLSQDQAATSK 31 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 EVAATEEDVT(0.006)RLPS(0.819)PT(0.05)S(0.069)PFS(0.033)S(0.012)LS(0.012)QDQAATSK;EVAATEEDVT(0.001)RLPS(0.943)PT(0.028)S(0.028)PFSSLSQDQAATSK;EVAATEEDVT(0.008)RLPS(0.667)PT(0.118)S(0.118)PFS(0.035)S(0.045)LS(0.008)QDQAATSK 113.43 7.9969e-17 133343000.0 147499.0 123434.0 141517.0 130057.0 137952.0 135206.0 113036.0 113693.0 155586.0 120144.0 True False 145395.6372119959 123148.19615676245 129882.0185314173 139621.82563743362 129837.9345840672 129423.55456058 118888.45099060434 118975.59183670227 138062.2662867869 140910.73031818273 1.031828001201087 0.8739447725427888 0.9217326334065397 0.9908530409441587 0.9214197832264962 0.9184790559834288 0.8437146746890666 0.8443330864019373 0.9797853291586534 1.0 17.10442195114748 -6.627567781462664 3.2723950726378948 0.9026703812803887 0.9471667116775144 0.04658033672384243 0.06143256600044018 0.6161365220086618 13.089342646930238 0.021223633152583916 0.021224677955885562 2.357394242633768e-07 6.627567781462664 0.04449633039712575 EVAATEEDVTRLPSPTS(ph)PFSSLSQDQAATSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVAATEEDVTRLPSPTSPFSSLSQDQAATSK 31 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 EVAATEEDVT(0.013)RLPS(0.268)PT(0.219)S(0.412)PFS(0.034)S(0.01)LS(0.043)QDQAATSK 77.149 5.7761e-07 18984000.0 32398.0 30070.0 32359.0 41914.0 44426.0 42548.0 37137.0 38182.0 39648.0 31200.0 True False 37882.34151033227 33055.150874293184 33130.561282190894 39565.69446702142 35721.04421470944 40316.707978526756 33619.11451140341 37179.76295717305 40227.77699335326 36856.31302093587 1.0278386090549418 0.8968653716261994 0.8989114365121492 1.0735120044304625 0.9691974396467289 1.0938887987961585 0.9121670551339847 1.0087759710542248 1.0914758882827553 1.0 15.16962413547577 -5.75374580636726 24.999778803771452 1.0179616988856957 0.9367711639217077 0.2520927521544345 0.06289012984128747 240.28769848377277 780790.6739429284 0.016755988710499752 0.02833317263888983 1.7630076372096296e-06 5.75374580636726 -0.08119053496398798 EVAATEEDVTRLPSPTS(ph)PFSSLSQDQAATSK ddPTM_PC-9_Lapatinib_30min_R1 1 EVAATEEDVTRLPSPTSPFSSLSQDQAATSK 31 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 EVAATEEDVT(0.004)RLPS(0.323)PT(0.13)S(0.455)PFS(0.032)S(0.042)LS(0.012)QDQAATSK 71.15899999999999 1.8889e-05 86715000.0 34584.0 36748.0 39933.0 33872.0 38487.0 34517.0 31248.0 32570.0 39321.0 30352.0 True False 34090.82581807116 36662.91226379041 36649.862885837705 36363.059873679595 36223.270328353305 33040.78837305695 32865.86854236172 34083.32110263072 34892.25491151353 35598.302758502214 0.9576531232216958 1.0299061871716322 1.0295396141346749 1.0214829656448925 1.0175561058090565 0.9281562831016029 0.9232425704484497 0.9574423065574479 0.9801662497288568 1.0 15.11952083814947 -6.748860147938955 24.9974038984359 0.9529816946802764 1.0138523888541473 0.4598683141954738 0.028643413656830877 187.2007906709158 372004.2180845902 0.009569439202361788 0.009507375982156617 1.782952823748372e-07 6.748860147938955 0.06087069417387092 EVAEAATGEDAS(ph)SPPPKTEAASDPQHPAASEGAAAAAASPPLLR ddPTM_PC-9_AZD4547_30min_R2 1 EVAEAATGEDASSPPPKTEAASDPQHPAASEGAAAAAASPPLLR 44 1 K7ERT7;Q99536-3;Q99536 K7ERT7 VAT1 Synaptic vesicle membrane protein VAT-1 homolog 1 EVAEAAT(0.002)GEDAS(0.301)S(0.301)PPPKT(0.301)EAAS(0.096)DPQHPAASEGAAAAAASPPLLR 78.818 1.6621e-12 11276000.0 13319.0 15142.0 22536.0 20836.0 21562.0 31144.0 21484.0 32274.0 26326.0 21844.0 True False 17554.164947589907 20036.35538205126 22237.157915239175 16032.582112991 18568.488487211987 29196.560756663737 23396.034379977216 27286.79488274009 27717.538614405814 21079.24820879613 0.8327699723306429 0.9505251412946653 1.0549312620153057 0.7605860490935719 0.8808895034246795 1.3850854863258524 1.1099083870654514 1.2944861511405148 1.3149206432722587 1.0 14.363535793736029 -6.746643042589724 24.977662146803667 1.2323497787036568 0.900285928372326 0.6310720065654228 0.12404648617634216 148.10469815741638 250014.67360868648 0.039865740300885 0.039706709219356436 1.7920782024117056e-07 6.746643042589724 -0.3320638503313308 EVAEAATGEDAS(ph)SPPPKTEAASDPQHPAASEGAAAAAASPPLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EVAEAATGEDASSPPPKTEAASDPQHPAASEGAAAAAASPPLLR 44 1 K7ERT7;Q99536-3;Q99536 K7ERT7 VAT1 Synaptic vesicle membrane protein VAT-1 homolog 1 EVAEAAT(0.001)GEDAS(0.425)S(0.425)PPPKT(0.134)EAAS(0.014)DPQHPAASEGAAAAAASPPLLR;EVAEAAT(0.001)GEDAS(0.297)S(0.297)PPPKT(0.297)EAAS(0.108)DPQHPAASEGAAAAAASPPLLR 88.751 4.1236000000000005e-17 12864300.0 10929.599999999999 12361.1 13143.0 14160.3 17575.3 13565.9 14309.1 10964.6 11881.5 9772.2 True False 12779.765410560145 13588.228316336059 13456.378965105072 13366.944299312005 14131.5461303467 12854.480322597927 12953.638459087233 10676.790867953996 12055.244459910373 11543.822503307361 1.107065307604884 1.177099553674094 1.165677916586967 1.1579305117938457 1.2241652300438561 1.113537592848041 1.1221273070835898 0.9248921546476518 1.0443026524755112 1.0 13.494833401923032 -7.624854375299717 5.19407602018956 0.9894714252982295 1.158598886107806 0.7695944380877205 0.04111921993171034 0.09287817877157759 3.933201330319173 0.019639412811709327 0.011048654007440036 2.3721689920467543e-08 7.624854375299717 0.16912746080957652 EVAEAATGEDASSPPPKT(ph)EAASDPQHPAASEGAAAAAASPPLLR ddPTM_PC-9_AZD4547_30min_R2 1 EVAEAATGEDASSPPPKTEAASDPQHPAASEGAAAAAASPPLLR 44 1 K7ERT7;Q99536-3;Q99536 K7ERT7 VAT1 Synaptic vesicle membrane protein VAT-1 homolog 1 EVAEAAT(0.007)GEDAS(0.168)S(0.168)PPPKT(0.487)EAAS(0.168)DPQHPAASEGAAAAAASPPLLR 65.977 7.8191e-09 9808900.0 2892.4 6491.8 10669.0 8035.6 9109.2 11098.0 7454.4 14977.0 10516.0 8187.8 True False 3812.123034342598 8590.147395931868 10527.522088999234 6183.116568782418 7844.544816237434 10404.040305595114 8117.827158913706 12662.648787221862 11071.854291160504 7901.147614172356 0.4824771312340451 1.0872024945494814 1.3324041776052795 0.7825593028652836 0.9928361295473846 1.3167758424020959 1.0274238066825494 1.6026341242516164 1.4012969801122086 1.0 12.947846499601228 -6.887882046491649 1.411405473014981 1.3294742627982623 0.9474658464499291 0.2672448960552337 0.26430889506176586 0.5731616567360678 2.36147493874613 0.13151166944127332 0.10654365679238352 1.294547390176987e-07 6.887882046491649 -0.38200841634833316 EVAEAATGEDASSPPPKT(ph)EAASDPQHPAASEGAAAAAASPPLLR ddPTM_PC-9_Lapatinib_30min_R1 2 EVAEAATGEDASSPPPKTEAASDPQHPAASEGAAAAAASPPLLR 44 1 K7ERT7;Q99536-3;Q99536 K7ERT7 VAT1 Synaptic vesicle membrane protein VAT-1 homolog 1 EVAEAAT(0.031)GEDAS(0.187)S(0.187)PPPKT(0.513)EAAS(0.083)DPQHPAASEGAAAAAASPPLLR;EVAEAAT(0.015)GEDAS(0.161)S(0.161)PPPKT(0.503)EAAS(0.161)DPQHPAASEGAAAAAASPPLLR 66.786 7.0326999999999995e-09 19444700.0 26717.0 36269.0 41901.0 33042.0 38068.0 41688.0 46057.0 35184.0 46855.0 30360.0 True False 26336.010680702264 36185.02135886071 38456.0615225374 35472.018904880795 35828.915084567634 39905.10141947444 48441.606101368234 36818.777085506896 41577.696494976364 35607.685547842855 0.7396159080689737 1.0162137977275199 1.0799932916411383 0.9961899617772186 1.0062129715346855 1.1206878741348558 1.3604255754359993 1.0340120824768801 1.167660741081083 1.0 15.119901045040821 -6.751474956361003 3.6784780636281704 1.1553171736579617 0.9748156683896817 0.321579167273903 0.12247638111129466 0.2798968402314402 8.129281565925336 0.043764330476958976 0.041117901128988325 1.772250239193261e-07 6.751474956361003 -0.18050150526828002 EVAENQQNQS(ph)SDPEEEKGSQPPPAAESQSSLRR ddPTM_PC-9_AZD4547_30min_R2 2 EVAENQQNQSSDPEEEKGSQPPPAAESQSSLRR 33 2 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;E9PJP4;E9PQN0;E9PRG1;E9PIG0;E9PQD2;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 EVAENQQNQS(0.498)S(0.498)DPEEEKGS(0.003)QPPPAAESQS(0.001)S(0.001)LRR;EVAENQQNQS(0.442)S(0.159)DPEEEKGS(0.388)QPPPAAES(0.003)QS(0.005)S(0.005)LRR 60.363 0.00016975 18037900.0 20864.6 16828.0 18932.0 23415.0 20806.0 20708.0 18583.7 17406.4 18884.800000000003 23583.0 True False 27499.10878935987 22267.321910524286 18680.949310050946 18017.033508143813 17917.44603770209 19413.125486417695 20237.613298602806 14716.64083928014 19883.011973916684 22757.366348106538 1.2083607728909218 0.9784665575934263 0.8208748334187291 0.7917011675493315 0.7873251132679007 0.8530479840885854 0.8892774756551133 0.646675920849892 0.873695649565838 1.0 14.474045987441126 -4.852436434860603 2.0155469752508384 0.8189244530666101 1.287945204825118 0.6432226591805048 0.08590566548708063 0.3541041047115304 1.8019082311073265 0.022121502490762782 0.29504040078566995 1.4046352567680651e-05 4.852436434860603 0.469020751758508 EVAENQQNQSSDPEEEKGS(ph)QPPPAAESQSSLRR ddPTM_PC-9_Lapatinib_30min_R1 1 EVAENQQNQSSDPEEEKGSQPPPAAESQSSLRR 33 2 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;E9PJP4;E9PQN0;E9PRG1;E9PIG0;E9PQD2;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 EVAENQQNQS(0.301)S(0.301)DPEEEKGS(0.392)QPPPAAES(0.001)QS(0.003)S(0.003)LRR 56.573 0.00032871 9932200.0 10432.0 11923.0 14082.0 8764.0 11294.0 11510.0 6218.0 8451.3 10213.0 8121.7 True False 10283.237767005496 11895.393026046931 12924.232318091974 9408.533795846954 10629.70912485833 11017.744131120488 6539.937615092332 8843.978250987499 9062.704392342199 9525.525023515002 1.079545509735157 1.2487913261139518 1.3567999964502555 0.9877181333964018 1.115918450543934 1.1566547884680107 0.6865697795079686 0.9284504769191183 0.9514125856548307 1.0 13.217582897262451 -7.21220421564385 16.730859244920136 0.8856491453290951 1.1611669422613915 0.5413783889822752 0.119845798915155 7.608989230818423 2585.2171370637507 0.046989434176355885 0.03639550402370903 6.134734674467015e-08 7.21220421564385 0.2755177969322964 EVAENQQNQSSDPEEEKGSQPPPAAES(ph)QSSLRR ddPTM_PC-9_AZD4547_30min_R2 2 EVAENQQNQSSDPEEEKGSQPPPAAESQSSLRR 33 2 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;E9PJP4;E9PQN0;E9PRG1;E9PIG0;E9PQD2;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 EVAENQQNQSSDPEEEKGS(0.012)QPPPAAES(0.329)QS(0.329)S(0.329)LRR;EVAENQQNQSSDPEEEKGS(0.002)QPPPAAES(0.647)QS(0.175)S(0.175)LRR 53.615 0.00068515 67764000.0 35737.0 44698.0 48969.0 61733.0 75040.0 76070.0 67677.0 79534.0 68345.0 77129.0 True False 47100.62262422256 59145.75438296974 48319.63906422381 47501.41061534236 64621.991284685406 71313.33087462792 73700.12189227877 67243.84780950133 71957.5771709171 74428.73718624035 0.6328284531600257 0.7946628764501464 0.6492067565692444 0.6382133086106417 0.8682397918828599 0.9581424268449313 0.9902105648771334 0.9034661926513607 0.9667983079016944 1.0 16.183572137862846 -6.441569816239615 3.458426028421655 0.9574348912970909 0.6855696761578627 0.8781839754348516 0.04998680653937705 0.08405026372262948 1.9217420890334818 0.016613964967067348 0.01857159594359036 3.61768029013336e-07 6.441569816239615 -0.27186521513922823 EVAENQQNQSSDPEEEKGSQPPPAAES(ph)QSSLRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EVAENQQNQSSDPEEEKGSQPPPAAESQSSLRR 33 2 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;E9PJP4;E9PQN0;E9PRG1;E9PIG0;E9PQD2;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 EVAENQQNQSSDPEEEKGSQPPPAAES(0.333)QS(0.333)S(0.333)LRR;EVAENQQNQSSDPEEEKGSQPPPAAES(0.333)QS(0.333)S(0.333)LRR 72.578 1.9741e-06 54448000.0 109427.0 105068.0 111113.0 113159.0 144093.0 97000.0 89074.0 110371.0 81072.0 66678.0 True False 127950.82981823332 115498.45666977845 113762.35531839915 106819.06809642777 115859.01103025563 91913.14924125928 80636.26588008567 107473.87819774087 82257.52462684458 78766.19357724227 1.6244384044375333 1.466345540190597 1.4443043411363758 1.3561537411564184 1.4709230669708342 1.1669111463552495 1.023742067731247 1.364467080567329 1.0443252478130547 1.0 16.26528893786682 -4.898036577881917 0.22124373254170734 0.9661828622830743 2.0984343712853293 0.7326005864109002 0.10841154193846687 6.320109727822945 0.2914813217200868 0.20419552249236148 1.9844603158364438 1.2646298312002703e-05 4.898036577881917 1.1322515090022551 EVAENQQNQSSDPEEEKGSQPPPAAES(ph)QSSLRR ddPTM_PC-9_Lapatinib_30min_R1 2 EVAENQQNQSSDPEEEKGSQPPPAAESQSSLRR 33 2 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;E9PJP4;E9PQN0;E9PRG1;E9PIG0;E9PQD2;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 EVAENQQNQSSDPEEEKGSQPPPAAES(0.333)QS(0.333)S(0.333)LRR;EVAENQQNQSSDPEEEKGSQPPPAAES(0.333)QS(0.333)S(0.333)LRR 74.058 2.7606000000000002e-08 80569000.0 107836.0 169463.0 161995.0 165336.0 129391.0 106633.0 96148.0 101029.0 123403.0 114408.0 True False 106298.23886529965 169070.61883527564 148676.39641878323 177495.3609847273 121780.47577249377 102072.55516366378 101126.07298422279 105723.17616449721 109504.05464880094 134183.27036092267 0.7921869736769823 1.2599977506921234 1.1080099331226414 1.3227830899284605 0.9075682493423495 0.7606950917883554 0.7536414391467469 0.7879013224236208 0.8160782961561436 1.0 17.033845285528827 -6.47168175848981 6.682039786507607 0.8086101300446267 1.12947307450346 0.4822446422129003 0.14531294872706038 0.18157568776257899 19.116630860458763 0.04391207947862835 0.0492242501690743 3.3753455600906594e-07 6.47168175848981 0.32086294445883334 EVAENQQNQSSDPEEEKGSQPPPAAESQS(ph)SLRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVAENQQNQSSDPEEEKGSQPPPAAESQSSLRR 33 2 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;E9PJP4;E9PQN0;E9PRG1;E9PIG0;E9PQD2;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 EVAENQQNQSSDPEEEKGS(0.004)QPPPAAES(0.174)QS(0.411)S(0.411)LRR 70.637 4.6106e-06 51297000.0 61984.0 69975.0 68440.0 63483.0 87012.0 56935.0 53193.0 62527.0 48371.0 38070.0 True False 72476.66696019619 76921.6555513357 70071.86916014535 59926.25332466292 69962.6232208682 53949.228371660756 48154.17395602989 60885.732502832754 49078.33436605858 44971.78963804579 1.611602908034629 1.710442394453001 1.5581294345659102 1.3325298772180898 1.555700224161868 1.1996237820613687 1.0707640132535847 1.3538650116633093 1.0913137938486372 1.0 15.456732676288421 -6.041843013883006 0.34614115017562 1.0203510529745865 1.8855751888198218 0.7695847466179382 0.11503207891274686 1.362541768192924 0.24723376435576264 0.12757804047347604 0.46053200519975696 9.08148742915785e-07 6.041843013883006 0.8652241358452353 EVAES(ph)PRPR ddPTM_PC-9_AZD4547_30min_R2 1 EVAESPRPR 9 1 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 EVAES(1)PRPR 66.267 0.023075 13137000.0 24480.0 32882.0 43701.0 58531.0 59412.0 49078.0 59589.0 91114.0 57576.0 65107.0 True False 32264.130784368277 43510.4634574435 43121.49618627384 45037.582244935526 51163.669325769355 46009.14490160366 64892.30556081093 77034.42489142911 60619.34981626636 62827.6237470285 0.5135341567950713 0.692537149465268 0.6863461263456319 0.7168436359502715 0.8143499033446924 0.7323075767890984 1.0328626437010533 1.2261234835428985 0.9648518629376528 1.0 15.939111395361502 -7.255779589008872 3.2161308572207687 1.0835905469570906 0.6928994045660251 0.7809289574378377 0.09440147601099562 0.11559913927061378 2.4850219337019452 0.041873529534759604 0.028963197199534 5.549072653012724e-08 7.255779589008872 -0.3906911423910655 EVAES(ph)PRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EVAESPRPR 9 1 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 EVAES(1)PRPR;EVAES(1)PRPR 74.611 0.012823 25340000.0 31975.0 44354.0 64881.0 70620.0 88505.0 69185.0 65399.0 71670.0 64229.0 50400.0 True False 37387.735964963096 48757.171994625845 66428.00910256272 66663.39035312903 71163.0805884586 65556.81680676818 59203.93327224257 69788.73844064209 65168.22761567007 59537.12103381952 0.627973528376109 0.8189373477923089 1.1157410359971704 1.119694556867496 1.1952724510819905 1.1011082778008232 0.9944036971255682 1.172188665303437 1.0945814390093174 1.0 15.861501840113439 -5.06370517919501 2.532007526696249 1.1073132815489357 0.6264772935274608 0.8624542098964569 0.062073660230701176 0.1061582289131678 1.2124284425764904 0.01674295585568907 0.0832912553203083 8.635645796374343e-06 5.06370517919501 -0.48083598802147487 EVAGGAAVGLS(ph)PPAPAPFPLEPGDAATAAAR ddPTM_PC-9_AZD4547_30min_R2 2 EVAGGAAVGLSPPAPAPFPLEPGDAATAAAR 31 0 G3V2N2;Q9UIU6 G3V2N2 SIX4 Homeobox protein SIX4 1 EVAGGAAVGLS(1)PPAPAPFPLEPGDAATAAAR;EVAGGAAVGLS(1)PPAPAPFPLEPGDAATAAAR 142.71 4.3250000000000003e-16 7369300.0 32204.9 35953.9 41386.1 49607.5 43736.3 44934.6 35408.8 49190.7 44178.9 45111.6 True False 42445.38829646655 47575.29505816491 40837.293272802635 38171.257303234815 37664.2696884913 42124.83235860464 38560.11460406522 41589.4076048337 46514.1064609881 43532.25661490241 0.9750330352030546 1.092874543100953 0.938092725908052 0.8768499561350016 0.8652037045007605 0.9676693935545724 0.8857825806086266 0.9553698989864997 1.0684974792936626 1.0 15.409797187700665 -10.545298194604236 11.780116432090384 0.9999993283760333 0.9546455221445852 0.026980545694179625 0.0719189930638078 0.0 0.0 0.07445711032626501 0.01805850179137989 2.8490613776538782e-11 10.545298194604236 -0.045353806231448135 EVCGFAPYER ddPTM_PC-9_AZD4547_30min_R2 2 EVCGFAPYER 10 0 Q9Y3U8;J3QSB5 Q9Y3U8 RPL36 60S ribosomal protein L36 0 ; 114.97 0.0053602 23943000.0 44019.0 48866.0 66784.0 92307.0 75147.0 69150.0 61465.0 77360.0 58670.0 66411.0 False True 58016.12634792101 64660.978873287364 65898.40052410963 71027.04727893356 64714.136181639864 64826.039568562075 66935.26592651736 65405.789555951305 61771.17642282106 64085.971103935146 0.9052859049889403 1.008972443725939 1.0282812195704278 1.108308824153438 1.0098019124448618 1.0115480572717963 1.0444605078693618 1.0205944987534896 0.9638798532465095 1.0 15.967720954273341 -4.757653233210623 3.3783522632984107 1.0266833442158152 0.8857186615535306 0.502237783630813 0.03491736369178824 0.2867259649358037 5.019111258150093 0.00909667522788725 0.10914979209118915 1.747216678809007e-05 4.757653233210623 -0.14096468266228457 EVCGFAPYER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EVCGFAPYER 10 0 Q9Y3U8;J3QSB5 Q9Y3U8 RPL36 60S ribosomal protein L36 0 ;; 98.044 0.022629 14035300.0 37086.0 47200.0 51902.0 51148.0 57349.0 54301.0 52718.0 46593.0 50099.0 41576.1 False True 43363.927318111695 51885.70406606712 53139.54051943111 48282.34338405334 46111.875133241156 51453.35996855272 47724.16939473209 45369.98311936417 50831.60309700375 49113.517813773506 0.8829326272766114 1.0564444653059686 1.0819738207497842 0.9830764631262664 0.9388835739294048 1.0476415100960865 0.9717114863506726 0.9237779157134721 1.0349819226907102 1.0 15.583832540521387 -5.930414357556535 24.999999984062544 0.9825441537698472 1.0154622801618922 0.01836186530962436 0.06036273042406422 158.91576462366822 57090.311730057314 0.01695081433900888 0.025142120227327515 1.1737771273619493e-06 5.930414357556535 0.032918126392045055 EVCGFAPYER ddPTM_PC-9_Lapatinib_30min_R1 4 EVCGFAPYER 10 0 Q9Y3U8;J3QSB5 Q9Y3U8 RPL36 60S ribosomal protein L36 0 ;;; 126.31 0.0016140999999999998 48410000.0 112769.0 114219.0 135672.0 120838.0 130321.0 126840.0 120325.0 115111.0 119904.0 109651.0 False True 111160.8933806979 113954.53292309458 124517.57186906485 129724.82962375117 122655.7750009439 121415.3488784815 126554.8397452533 120459.47729336572 106399.14887490444 128604.02924922667 0.8643655570485661 0.8860883565495271 0.968224499620906 1.0087151264316334 0.9537475281061729 0.9441022150494682 0.9840658996772008 0.9366695429108421 0.8273391548931134 1.0 16.97257631839983 -5.161451929263746 4.573818074264933 0.9533275456243726 0.8700688279953864 0.3005175358989003 0.04769796432218341 0.2781692571041641 9.524637347319619 0.012577638138729114 0.03645128874860112 6.895219100317661e-06 5.161451929263746 -0.08325871762898618 EVDAT(ph)SPAPSTSSTVK ddPTM_PC-9_AZD4547_30min_R2 2 EVDATSPAPSTSSTVK 16 0 H3BM18;X6RHM1;Q16666-3;Q16666-2;Q16666;Q16666-6 H3BM18 IFI16 Gamma-interferon-inducible protein 16 1 EVDAT(0.5)S(0.5)PAPSTSSTVK;EVDAT(0.49)S(0.49)PAPS(0.015)T(0.004)S(0.001)STVK 232.26 2.049e-29 54104000.0 79966.0 84086.0 94853.0 132599.0 102795.0 102054.0 83983.0 116840.0 83877.0 96242.0 True False 105393.52460387212 111265.15510864893 93595.18724415076 102030.34918412814 88523.68862085891 95672.54724699969 91457.32430337102 98785.06271609802 88310.56698171068 92872.59687378509 1.134818322643687 1.1980407445681693 1.0077804475667638 1.0986055372478551 0.953173396681947 1.0301482941951086 0.9847611392590061 1.0636621139209452 0.9508786224824287 1.0 16.502965355207387 -5.267297914500398 24.768751333242374 1.0141921070919473 1.1664295380994334 0.650795456525652 0.04546057270929075 214.98675166652208 908926.5564583567 0.01118400375227684 0.02432552613818619 5.403835070162222e-06 5.267297914500398 0.1522374310074861 EVDAT(ph)SPAPSTSSTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EVDATSPAPSTSSTVK 16 0 H3BM18;X6RHM1;Q16666-3;Q16666-2;Q16666;Q16666-6 H3BM18 IFI16 Gamma-interferon-inducible protein 16 1 EVDAT(0.927)S(0.073)PAPSTSSTVK;EVDAT(0.667)S(0.315)PAPS(0.014)T(0.004)SSTVK 264.85 1.5690999999999996e-68 11954100.0 71286.0 77395.0 73368.0 80707.0 83471.0 68545.0 73845.0 62692.0 57138.0 55754.0 True False 83353.31183732145 85078.2641142642 75117.37136968954 76185.24844562417 67115.45675158729 64950.379533423904 66849.86700849788 61046.40142766469 57973.53515552406 65861.75885157888 1.2655798036787966 1.2917703018832247 1.14053090411643 1.1567448208801943 1.0190352933457736 0.986162238390736 1.0150027599345735 0.9268868990461412 0.8802305946029907 1.0 16.007153419459755 -5.919277776478306 0.69675113045477 0.9367803969277932 1.3221573756663576 0.898587913887101 0.04200013101964272 0.2780551708977744 0.2519592099831762 0.023273016978623353 0.06817640147828183 1.2042654410240358e-06 5.919277776478306 0.38537697873856436 EVDAT(ph)SPAPSTSSTVK ddPTM_PC-9_Lapatinib_30min_R1 4 EVDATSPAPSTSSTVK 16 0 H3BM18;X6RHM1;Q16666-3;Q16666-2;Q16666;Q16666-6 H3BM18 IFI16 Gamma-interferon-inducible protein 16 1 EVDAT(0.5)S(0.5)PAPSTSSTVK;EVDAT(0.5)S(0.5)PAPSTSSTVK;EVDAT(0.5)S(0.5)PAPSTSSTVK;EVDAT(0.5)S(0.5)PAPSTSSTVK 281.99 3.524999999999999e-83 56744800.0 214766.0 250596.0 281781.0 211752.0 259128.0 267982.0 256935.0 235050.0 250601.0 188170.0 True False 211703.39745673907 250015.76035857174 258614.05388611462 227324.94846396428 243886.60050524943 256521.03455655318 270237.83710739 245971.2810922122 222375.6764344805 220694.93377923509 0.9592580755320356 1.1328568176769602 1.171816903349538 1.0300415354860901 1.1050847263635575 1.1623331363517186 1.224485911297418 1.1145307093377208 1.0076156829994416 1.0 17.75169398626791 -4.757223988979814 24.923239090006184 1.1142059172673997 0.9592578387760946 0.27153355742130514 0.07050972103188892 158.3431672074053 936066.1009361586 0.017735761032777037 0.13402424750253694 1.7489444314364477e-05 4.757223988979814 -0.1549480784913051 EVDATS(ph)PAPSTSSTVK ddPTM_PC-9_AZD4547_30min_R2 2 EVDATSPAPSTSSTVK 16 0 H3BM18;X6RHM1;Q16666-3;Q16666-2;Q16666;Q16666-6 H3BM18 IFI16 Gamma-interferon-inducible protein 16 1 EVDAT(0.019)S(0.981)PAPSTSSTVK;EVDAT(0.127)S(0.873)PAPSTSSTVK 239.51 2.4072e-37 16433100.0 54744.0 60779.0 69967.0 81119.0 74408.0 72089.0 59567.0 78519.0 62073.0 62698.0 True False 72151.45325406287 80424.62315187513 69039.19186437431 62418.2678260567 64077.733575571336 67581.26343395632 64868.34760343056 66385.69273712189 65354.05205545888 60502.96210378595 1.19252761757838 1.329267532619574 1.1410877990724724 1.0316563959130671 1.0590842389774782 1.1169909882763815 1.0721515996548447 1.0972304566385491 1.0801793793723924 1.0 15.884718155123988 -5.474519372609432 4.91635200386982 1.072109210481748 1.25871715228797 0.7570465537129898 0.04385969022938514 0.08942727994676933 4.824871838813098 0.011071228664121425 0.02301707863534681 3.353363457411626e-06 5.474519372609432 0.1866079418062221 EVDATS(ph)PAPSTSSTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EVDATSPAPSTSSTVK 16 0 H3BM18;X6RHM1;Q16666-3;Q16666-2;Q16666;Q16666-6 H3BM18 IFI16 Gamma-interferon-inducible protein 16 1 EVDAT(0.043)S(0.881)PAPS(0.007)T(0.051)S(0.015)S(0.002)T(0.001)VK;EVDAT(0.002)S(0.586)PAPS(0.031)T(0.285)S(0.084)S(0.009)T(0.003)VK 179.55 5.3605e-06 38659000.0 106291.0 113000.0 100029.0 115932.0 126419.0 102610.0 115740.0 91202.0 87180.0 84228.0 True False 124283.96695705662 124217.89320901662 102414.07072209482 109436.70589661544 101648.10445638496 97228.95096541868 104776.26931496458 88808.04413650656 88454.84257164405 99497.86965151907 1.249111839201666 1.2484477672142817 1.029309180998442 1.0998899401555642 1.0216108627490907 0.9771963088853356 1.0530503786858207 0.8925622673887139 0.8890124269137413 1.0 16.602378015998788 -4.441404062447737 0.42735966093465977 0.936577995256554 1.6331367414252136 0.7757269411966738 0.05625481090477275 3.2015052079070347 0.3675780241703878 0.042225349639770676 1.204329870371591 3.619061285509107e-05 4.441404062447737 0.6965587461686595 EVDDLEQWIAER ddPTM_PC-9_AZD4547_30min_R2 2 EVDDLEQWIAER 12 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 ; 95.094 0.021672999999999998 5814300.0 10282.1 8633.7 14814.3 18033.0 14858.9 11992.7 9682.8 14924.4 12391.6 13446.6 False True 13551.59391903402 11424.374683794482 14617.852702508331 13875.77045707269 12795.998218283752 11242.794573158279 10544.550441930893 12618.176908594105 13046.594678047217 12975.838626826504 1.0443713357391164 0.8804343990665471 1.1265439655119551 1.0693544252612428 0.9861403633541692 0.8664406900001596 0.8126295914416569 0.9724363312061417 1.005452907766164 1.0 13.663540162345756 -6.547239555778364 8.180781804282358 0.9224851453606201 1.0265880805735224 0.2497779845410707 0.08006025938615312 0.29376742426247626 81.83268099191075 0.02768391867850662 0.02795375556451364 2.8363540708711377e-07 6.547239555778364 0.10410293521290226 EVDDLEQWIAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVDDLEQWIAER 12 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 84.821 0.04608 1421000.0 4127.5 5167.5 4288.4 4490.1 5853.9 4568.9 6419.2 4906.3 5259.1 3844.6 False True 4826.204228159032 5680.49524918224 4390.651719847565 4238.53425410061 4706.870317572761 4329.2988409112295 5811.126905016582 4777.514823654552 5336.004388260294 4541.595546163144 1.0626671131550525 1.2507708340477979 0.9667641416367205 0.9332698632051092 1.036391345228715 0.9532550393151438 1.279534217864462 1.0519463424458215 1.1749184474976613 1.0 12.148983516570821 -7.23176758211088 24.996202913777072 1.1309287309871 1.036206885726542 0.14993073201354323 0.10790572861685678 1396.6574055805872 1176577.5000909362 0.0421937109408119 0.03267953067677037 5.864519273164567e-08 7.23176758211088 -0.09472184526055782 EVDDLEQWIAER ddPTM_PC-9_Lapatinib_30min_R1 2 EVDDLEQWIAER 12 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 ; 185.25 0.00048605 6142400.0 28834.0 24051.5 29435.0 26065.0 30259.0 27290.8 26972.8 24131.3 27080.3 23986.0 False True 28422.821872491997 23995.810229469767 27014.967922385826 27981.907050291058 28479.2251114829 26123.63610196203 28369.31960507601 25252.528293641764 24030.231445798938 28131.94814066399 1.0103396227795385 0.8529736408401968 0.9602949567270246 0.9946665232843916 1.012344575963331 0.9286109860340956 1.008437789776418 0.8976459137268172 0.8541972040345074 1.0 14.779921842460022 -10.569848344596103 5.810036648886767 1.0000001525388922 0.9474561184073852 0.06860732934519287 0.05893863636772002 1.1801012851515048e-07 1.9281194909712927e-08 0.05782932065477601 0.014025629675733875 2.6924748505824292e-11 10.569848344596103 -0.05254403413150699 EVDDLGPEVGDIK ddPTM_PC-9_Lapatinib_30min_R1 1 EVDDLGPEVGDIK 13 0 O43143 O43143 DHX15 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 0 96.604 0.014843 2815800.0 21240.0 20516.0 24635.0 24825.0 29463.0 23226.0 23640.0 26030.0 22690.0 22607.0 False True 20937.11370506105 20468.49646249927 22609.605393850004 26650.713313772336 27730.044266486686 22232.67812245042 24863.963528591645 27239.448827186898 20134.413263707487 26514.589828066 0.7896450158508155 0.771971076876065 0.8527231814809172 1.0051339087871631 1.0458409670412518 0.8385073375307082 0.9377464893789476 1.0273381185159285 0.759371100751292 1.0 14.694498810185673 -5.542703376420256 4.6553775779384745 0.9452549823620077 0.7859476771775993 0.38879547882704857 0.08356263165904375 0.18736935538945684 10.28369576652285 0.022546191356023287 0.04265056345073439 2.866134874626475e-06 5.542703376420256 -0.1593073051844084 EVDEDFDSK ddPTM_PC-9_AZD4547_30min_R2 3 EVDEDFDSK 9 0 Q96C19;H0Y4Y4 Q96C19 EFHD2 EF-hand domain-containing protein D2 0 ;; 172.23 0.0068065 11656800.0 76477.0 88069.0 109081.0 103769.0 98907.0 103607.0 95921.0 112750.0 101213.0 101210.0 False True 100795.09517958049 116535.58196683877 107634.51466774086 79846.66026506836 85175.47030909364 97128.43791149677 104457.78317640067 95327.07823724815 106562.91254956518 97666.66870592635 1.0320316697098968 1.193197060070991 1.102059854133324 0.8175425795005469 0.8721037733513404 0.9944891046089614 1.0695335938089823 0.9760451492850372 1.0910878190227349 1.0 16.57557866848635 -5.555900157737917 24.999610248162195 0.9728530139185384 1.1213680460461726 0.34562597613907153 0.08482570870647023 196.47649792557348 148746.13576674892 0.024461599128486312 0.04236910744420437 2.780352384249035e-06 5.555900157737917 0.14851503212763417 EVDEDFDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EVDEDFDSK 9 0 Q96C19;H0Y4Y4 Q96C19 EFHD2 EF-hand domain-containing protein D2 0 ; 156.92 2.0379000000000002e-15 0.0 39640.0 36495.0 38954.0 49362.0 67419.0 37187.0 53882.0 44169.0 34314.0 37472.0 False True 46350.269074312346 40117.98241294743 39882.811093867655 46596.40717376321 54208.73092134098 35236.84825602791 48777.90688810185 43009.61055092392 34815.777334289814 44265.37697181123 1.0470998384093464 0.9063061281166788 0.9009933682314634 1.0526603490451785 1.2246305042395056 0.7960363305720223 1.1019426519097364 0.9716309561378638 0.7865239091143617 1.0 15.433891087340013 -9.974823730056691 5.635915448833368 0.9999999827174468 0.9799315421784522 0.00232006239743765 0.12942571242186215 85273637.36148141 10.49026639813409 0.13903294598883217 0.03089621010748509 1.0596837386785706e-10 9.974823730056691 -0.020068440538994592 EVDEDFDSK ddPTM_PC-9_Lapatinib_30min_R1 4 EVDEDFDSK 9 0 Q96C19;H0Y4Y4 Q96C19 EFHD2 EF-hand domain-containing protein D2 0 ;;; 136.57 0.0037243000000000003 14180600.0 85826.0 137240.0 124825.0 116625.0 139912.0 120195.0 121321.0 121310.0 122663.0 111020.0 False True 84602.10550143925 136922.2292120003 114562.3703384344 125201.99154959484 131682.65123757554 115054.54003823003 127602.40775178807 126946.50546392817 108847.40124134642 130209.65907514871 0.6497375548200484 1.051552013764029 0.8798300460361109 0.9615415049764952 1.0113124646273493 0.8836098708455099 0.9799765137096634 0.9749392354269413 0.8359395302504145 1.0 16.990476947386938 -4.749353718983688 24.996000524895603 0.9508535332609392 0.6497368709342626 0.6714662556317643 0.06365897440474427 318.50794892741163 658709.3166642996 0.014810775719783332 0.2446632049248932 1.7809276678903914e-05 4.749353718983688 -0.30111666232667667 EVDEDS(ph)EPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVDEDSEPER 10 0 F8WC91;B9A018;Q53GS9-3;Q53GS9 F8WC91 USP39 U4/U6.U5 tri-snRNP-associated protein 2 1 EVDEDS(1)EPER 98.105 0.013061000000000001 0.0 10468.0 11039.0 9739.4 10886.0 9792.7 8379.7 9944.0 9864.1 10111.0 8336.4 True False 12240.025647575721 12134.87896579057 9971.62423288019 10276.092712888185 7873.890732485141 7940.253780381236 9002.032331674489 9605.177826877862 10258.854246867297 9847.723329093915 1.2429294811130647 1.2322522232056956 1.012581680013311 1.0434993317215466 0.7995645764359237 0.8063034992994482 0.9141231968894847 0.9753703984047276 1.041748829047496 1.0 13.265574514665694 -5.4011927856957795 1.5898477623872496 0.9212227321566879 1.2671871639763517 0.6834799406254599 0.07995192477144719 0.2705012490910508 1.2272627854539158 0.0262312491919581 0.0990513108409544 3.970152730962109e-06 5.4011927856957795 0.34596443181966374 EVDEDS(ph)EPER ddPTM_PC-9_Lapatinib_30min_R1 1 EVDEDSEPER 10 0 F8WC91;B9A018;Q53GS9-3;Q53GS9 F8WC91 USP39 U4/U6.U5 tri-snRNP-associated protein 2 1 EVDEDS(1)EPER 92.11200000000001 0.0076408000000000005 2763200.0 9988.2 9734.8 12228.0 12330.0 9684.7 11891.0 11666.0 13968.0 10880.0 8998.1 True False 9845.766436388452 9712.259668704324 11222.661041445008 13236.789331674232 9115.064986852789 11382.449649274862 12270.008397823613 14617.004272691005 9654.579828520826 10553.409595785399 0.9329464896653352 0.9202959082136833 1.063415661032135 1.254266615119389 0.8637080655424361 1.0785566073186952 1.1626582183187273 1.3850504085929196 0.9148303911540088 1.0 13.365421559735845 -7.000252732746139 24.999940515660764 1.1438487502533916 1.014207055188402 0.09206386580068682 0.15159040733232568 18.994763639939993 1879172.4464728942 0.053819070797612785 0.04697581587912059 9.994182306396862e-08 7.000252732746139 -0.12964169506498968 EVDEQMLNVQNK ddPTM_PC-9_AZD4547_30min_R2 2 EVDEQMLNVQNK 12 0 P68371;Q5JP53;P07437;Q5ST81;Q9BVA1;Q13885 P68371;Q5JP53 TUBB4B;TUBB;TUBB2B;TUBB2A Tubulin beta-4B chain;Tubulin beta chain;Tubulin beta-2B chain;Tubulin beta-2A chain 0 ; 150.61 2.2181999999999998e-07 0.0 18248.4 18059.2 28443.0 34557.0 27875.2 27742.0 26839.2 38255.0 26797.0 25834.6 False True 24051.011609700407 23896.483233096038 28065.827235673933 26590.417550327795 24005.20964097635 26007.28835446205 29227.836805580188 32343.568762447227 28213.434712840244 24930.13851744025 0.964736380942094 0.9585379245437765 1.125779033118491 1.0665972646612483 0.9628991681768294 1.0432067329376555 1.1723896674353982 1.2973681931137608 1.1316998777645426 1.0 14.605603278338307 -7.2296024034921125 4.765362158863377 1.1759174208922836 1.0204535445482918 0.3499951560623682 0.08442277677489853 0.1966291792550404 11.494381884467261 0.033895076986186705 0.025046620416744315 5.893829884416339e-08 7.2296024034921125 -0.15546387634399172 EVDEQMLNVQNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EVDEQMLNVQNK 12 0 P68371;Q5JP53;P07437;Q5ST81;Q9BVA1;Q13885 P68371;Q5JP53 TUBB4B;TUBB;TUBB2B;TUBB2A Tubulin beta-4B chain;Tubulin beta chain;Tubulin beta-2B chain;Tubulin beta-2A chain 0 ;;; 156.58 0.0010652 31381100.0 87568.0 86586.0 86095.0 100731.0 122115.0 99548.0 108445.0 93383.0 90945.0 77651.0 False True 102391.53285316285 95181.6858530613 88147.83131710594 95087.36864430849 98187.44235986243 94327.52763576154 98172.30452619081 90931.79519746697 92274.89857396373 91728.51161502211 1.1162454404895683 1.037645593253839 0.9609643693670292 1.0366173719615472 1.0704135566043846 1.0283337860277 1.0702485279409397 0.991314408099208 1.0059565662771763 1.0 16.485082610340825 -7.487505412439185 0.006959271888132811 1.460023572316465e-07 2.0523585162725344 0.16592829591591762 0.03928740673001319 5838.936473471328 30.50427418024059 4463.67414270979 4529.051271247139 3.254577274227171e-08 7.487505412439185 2.052358370270177 EVDEQMLNVQNK ddPTM_PC-9_Lapatinib_30min_R1 2 EVDEQMLNVQNK 12 0 P68371;Q5JP53;P07437;Q5ST81;Q9BVA1;Q13885 P68371;Q5JP53 TUBB4B;TUBB;TUBB2B;TUBB2A Tubulin beta-4B chain;Tubulin beta chain;Tubulin beta-2B chain;Tubulin beta-2A chain 0 ; 130.01 0.0021181999999999998 28841000.0 83844.0 97892.0 91344.0 105256.0 92482.0 91035.0 92281.0 82678.0 91647.0 84051.0 False True 82648.3691848935 97665.3370884666 83834.0489180369 112996.8773637227 87042.3905866077 87141.64526294985 97058.85864559918 86519.52171087824 81324.74977430582 98579.10335908218 0.8383964386837673 0.990730629114295 0.8504241371791013 1.1462558850035656 0.8829699968922309 0.8839768499976057 0.9845784282704887 0.8776659430115127 0.8249694611044898 1.0 16.58899423837064 EVDGLLTS(ph)EPMGSPVSSK ddPTM_PC-9_Lapatinib_30min_R1 2 EVDGLLTSEPMGSPVSSK 18 0 H3BUF6;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 EVDGLLT(0.077)S(0.549)EPMGS(0.365)PVS(0.005)S(0.003)K;EVDGLLT(0.063)S(0.557)EPMGS(0.377)PVS(0.002)S(0.001)K 88.18700000000001 0.010731000000000001 3641900.0 33339.0 38432.0 42663.0 35990.0 39194.0 37308.0 41602.0 41901.0 36984.0 30875.0 True False 32863.5797463762 38343.01306525506 39155.41282394248 38636.82465912047 36888.68597836881 35712.42380919575 43755.94799985063 43847.87342712096 32818.47246121454 36211.70261164851 0.9075403081379749 1.0588569523080353 1.0812916819698792 1.0669706717046732 1.0186951542704468 0.9862122251525355 1.2083372181946315 1.2108757739829683 0.9062946532278644 1.0 15.144168390984758 -7.196681868722566 24.99934495608423 1.0989532854127282 1.0265688943875713 0.07525055737434272 0.09639944343983235 463.9709954997805 179113.42364608365 0.03678835621374819 0.028496136988180952 6.357964977197425e-08 7.196681868722566 -0.07238439102515692 EVDGLLTSEPMGS(ph)PVSSK ddPTM_PC-9_AZD4547_30min_R2 10 EVDGLLTSEPMGSPVSSK 18 0 H3BUF6;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 EVDGLLTSEPMGS(1)PVSSK;EVDGLLTSEPMGS(0.988)PVS(0.011)S(0.001)K;EVDGLLTSEPMGS(0.975)PVS(0.019)S(0.006)K;EVDGLLT(0.012)S(0.116)EPMGS(0.858)PVS(0.01)S(0.004)K;EVDGLLT(0.006)S(0.037)EPMGS(0.907)PVS(0.039)S(0.01)K;EVDGLLTSEPMGS(0.997)PVS(0.002)SK;EVDGLLTSEPMGS(0.966)PVS(0.03)S(0.003)K;EVDGLLTSEPMGS(0.984)PVS(0.015)SK;EVDGLLTSEPMGS(1)PVSSK;EVDGLLTSEPMGS(0.998)PVS(0.002)SK 266.39 3.617399999999999e-78 661044800.0 1523242.0 1355185.0 2127034.0 2115318.0 2047539.0 2024851.0 1946442.0 2153188.0 1647905.0 1948948.0 True False 2007601.2705981492 1793222.0491629331 2098828.139380675 1627664.1164373136 1763273.552945808 1898236.7468755213 2119671.5672422075 1820462.2699379465 1735009.8940352665 1880715.9237336016 1.0674665138223822 0.9534784209212334 1.1159729722573286 0.865449213194341 0.9375544337633689 1.0093160391321285 1.127055681558877 0.9679623844115492 0.9225262955135302 1.0 20.842850520061205 -5.735443019721672 24.999998257521554 0.9804782319403128 1.0364230978763749 0.15093477814259626 0.07447053793595972 572.8464755919575 550886.5740065515 0.021250923858710778 0.03679208503757721 1.8388952046547303e-06 5.735443019721672 0.05594486593606207 EVDGLLTSEPMGS(ph)PVSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 EVDGLLTSEPMGSPVSSK 18 0 H3BUF6;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 EVDGLLT(0.003)S(0.023)EPMGS(0.942)PVS(0.026)S(0.006)K;EVDGLLT(0.003)S(0.285)EPMGS(0.634)PVS(0.059)S(0.019)K;EVDGLLTSEPMGS(0.933)PVS(0.057)S(0.01)K;EVDGLLTSEPMGS(1)PVSSK;EVDGLLTSEPMGS(0.976)PVS(0.018)S(0.006)K;EVDGLLTSEPMGS(0.998)PVS(0.001)SK;EVDGLLTSEPMGS(0.997)PVS(0.003)S(0.001)K;EVDGLLTSEPMGS(0.998)PVS(0.002)SK 187.75 8.296100000000001e-11 452353400.0 504683.8 567460.8 582632.0 652333.0 667823.8 571296.0 666130.0 566623.0 540974.0 458670.8 True False 590116.799380586 623794.5580062231 596524.1565241648 615784.8969021194 536968.52040326 541336.2320508702 603029.3440364359 551749.746636695 548884.7213277405 541824.1852039454 1.0891296761853904 1.1512859245502738 1.1009552043152708 1.136503156776464 0.9910383018453529 0.9990994252999402 1.1129612898498664 1.0183187862480032 1.0130310464475436 1.0 19.04746526645414 -6.254076750363902 24.990196715834376 1.026686302034283 1.1204187905913738 0.6335295489479387 0.036073755758043426 396.71032898188025 1346512.426469044 0.010972845843653278 0.013866405076010833 5.570872894021414e-07 6.254076750363902 0.09373248855709093 EVDGLLTSEPMGS(ph)PVSSK ddPTM_PC-9_Lapatinib_30min_R1 11 EVDGLLTSEPMGSPVSSK 18 0 H3BUF6;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 EVDGLLTS(0.002)EPMGS(0.997)PVS(0.001)SK;EVDGLLT(0.002)S(0.01)EPMGS(0.921)PVS(0.055)S(0.013)K;EVDGLLTSEPMGS(0.998)PVS(0.001)SK;EVDGLLTSEPMGS(0.999)PVSSK;EVDGLLT(0.001)S(0.023)EPMGS(0.917)PVS(0.049)S(0.011)K;EVDGLLTS(0.009)EPMGS(0.991)PVSSK;EVDGLLTSEPMGS(0.989)PVS(0.008)S(0.002)K;EVDGLLTSEPMGS(0.996)PVS(0.003)S(0.001)K;EVDGLLTSEPMGS(0.997)PVS(0.002)S(0.001)K;EVDGLLTSEPMGS(0.999)PVS(0.001)SK;EVDGLLTSEPMGS(0.999)PVSSK 171.25 5.1052999999999994e-08 512739800.0 923906.0 928179.0 1057916.0 981891.0 1132888.0 1022385.0 1004106.0 972273.0 1114373.0 835945.0 True False 910730.931016389 926029.858552649 970938.2301538554 1054102.539632353 1066253.7551835051 978659.9768458385 1056093.6955516092 1017448.3530370895 988860.5778720798 980436.9794233041 0.9289030811058184 0.9445072737845348 0.9903117186838098 1.0751354362953336 1.0875291095310162 0.9981875402348545 1.0771663224828654 1.0377498751990726 1.0085916776147412 1.0 19.903065374211224 -5.464174581447594 3.0897535405812975 1.0437231859119538 0.9367359330907669 0.6405251270999779 0.031037828023514534 0.15139491597760743 2.8255586718176207 0.008547223714977086 0.01939286876297016 3.4341986926295e-06 5.464174581447594 -0.10698725282118693 EVDIGIPDATGR ddPTM_PC-9_Lapatinib_30min_R1 4 EVDIGIPDATGR 12 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 ;;; 158.47 0.0015505999999999999 26561900.0 149980.0 139713.0 165118.0 157841.0 168476.0 151750.0 149541.0 136206.0 160161.0 145797.0 False True 147841.2576970366 139389.50313244102 151542.63541391218 169449.15368214052 158566.57291656034 145260.00624652754 157283.50127026753 142534.62800444954 142121.98160990103 170997.81718770877 0.8645797948095875 0.8151536985962197 0.88622555484179 0.9909433726638261 0.9273017370888289 0.8494845643969352 0.9197982983467755 0.833546476490899 0.8311333088766275 1.0 17.3836183834511 -5.435072550998349 6.618803342650032 0.9022881287738356 0.841354478505982 0.17732947818031974 0.05670972246277388 0.4579217745116233 28.89606743339567 0.015425388898102826 0.03233723351577238 3.672209493341135e-06 5.435072550998349 -0.06093365026785358 EVDIYTVK ddPTM_PC-9_Lapatinib_30min_R1 2 EVDIYTVK 8 0 E9PKG1;Q99873-2;Q99873-3;Q99873;Q9NR22-2;Q9NR22 E9PKG1 PRMT1;PRMT8 Protein arginine N-methyltransferase 1;Protein arginine N-methyltransferase 8 0 ; 157.86 0.00017327 6923800.0 50545.0 54729.0 56777.0 50948.0 59607.0 55652.0 64597.0 54763.0 47814.0 57638.0 False True 49824.21903118219 54602.27836303976 52109.01422555802 54694.88587754571 56101.033451870884 53271.89369114831 67941.51658445156 57307.48890216042 42428.683816258694 67600.65150219263 0.7370375569467128 0.8077182268172184 0.7708359766897789 0.8090881472610021 0.8298889464112819 0.7880381698602481 1.0050423342776196 0.8477357485275366 0.6276372027994807 1.0 16.044749530116867 -6.205527117165546 1.1954238768643688 0.8532426604804415 0.7716054984185184 0.11441479212911787 0.10093866609357595 1.2385854250355386 3.6292721676043143 0.04135237446017412 0.0640328718374522 6.229782477137831e-07 6.205527117165546 -0.08163716206192306 EVDKT(ph)PPPQPPLISSMDSISQK ddPTM_PC-9_AZD4547_30min_R2 4 EVDKTPPPQPPLISSMDSISQK 22 1 Q92625;A0A3B3ISP1;A0A3B3ITU5 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 EVDKT(1)PPPQPPLISSMDSISQK;EVDKT(1)PPPQPPLISSMDSISQK;EVDKT(1)PPPQPPLISSMDSISQK;EVDKT(1)PPPQPPLISSMDSISQK 77.065 0.00054396 42529100.0 216080.0 209838.0 213572.0 282224.0 266563.0 255124.0 236347.0 250120.0 213294.0 240126.0 True False 284788.9452567936 277664.02989425935 210739.89573453408 217161.61711733424 229555.32866230793 239171.05594923798 257381.42513519234 211469.70118581387 224568.2853916686 231719.2618286657 1.2290257745917033 1.198277724963432 0.9094621399681314 0.9371755088616869 0.9906614014334388 1.0321587168100086 1.1107467851572104 0.9126116642913162 0.9691394820587484 1.0 17.822018448676985 -5.216930936608257 8.589006909915753 0.9846630406407826 1.2148681865736033 0.7257418070594396 0.05677198612932868 0.208936122808097 37.718801013759574 0.015581393922044351 0.04119632705021083 6.068328231028316e-06 5.216930936608257 0.2302051459328207 EVDKT(ph)PPPQPPLISSMDSISQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EVDKTPPPQPPLISSMDSISQK 22 1 Q92625;A0A3B3ISP1;A0A3B3ITU5 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 EVDKT(1)PPPQPPLISSMDSISQK;EVDKT(1)PPPQPPLISSMDSISQK;EVDKT(1)PPPQPPLISSMDSISQK 75.91199999999999 0.00054446 36369100.0 161806.0 154687.0 127975.0 167124.0 180388.0 158673.0 172773.0 159989.0 142862.2 132166.0 True False 189196.5599858266 170043.30306923107 131026.40934788996 157760.58410331875 145042.26632609256 150351.9085521477 156406.69067180145 155789.45827235733 144951.28940627124 156126.6495745198 1.2118146421602574 1.089136950883384 0.839231545062719 1.0104654428520166 0.92900389985544 0.963012457910872 1.00179367902946 0.9978402706835675 0.9284211875505948 1.0 17.252357289315086 -5.006316590060807 4.872045410635965 0.9606924893881678 1.1912776091987909 0.7272015043388624 0.049610653866577495 0.08017881316384236 5.544684408592916 0.012159869824328309 0.0436184263416874 9.855607739896129e-06 5.006316590060807 0.23058511981062313 EVDKT(ph)PPPQPPLISSMDSISQK ddPTM_PC-9_Lapatinib_30min_R1 3 EVDKTPPPQPPLISSMDSISQK 22 1 Q92625;A0A3B3ISP1;A0A3B3ITU5 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 EVDKT(1)PPPQPPLISSMDSISQK;EVDKT(0.994)PPPQPPLIS(0.004)S(0.001)MDSISQK;EVDKT(0.999)PPPQPPLISSMDSISQK 75.611 0.00062312 14594200.0 107597.0 82476.0 91785.0 88094.0 100360.0 91113.0 82957.0 79353.0 85076.0 78595.0 True False 106062.6470491266 82285.03188931032 84238.79160034575 94572.72663296912 94457.02211535169 87216.30938477663 87252.10754828165 83040.03007236886 75493.84499000342 92180.04102874552 1.1506031659939477 0.8926556223125403 0.9138506629008404 1.0259566558825621 1.0247014544709967 0.9461517744126302 0.9465401248961569 0.9008460958101936 0.8189825492316861 1.0 16.49216678935847 -7.357824989769523 1.8242220949444035 0.8972649641764676 0.9902869728281407 0.19826361515357782 0.07849322820672709 0.5968863175922875 3.869100170759263 0.04383332395222616 0.025226830347228717 4.387074507097674e-08 7.357824989769523 0.0930220086516731 EVDPDGRR ddPTM_PC-9_AZD4547_30min_R2 1 EVDPDGRR 8 1 O00429-4;O00429-5;O00429-3;O00429-9;O00429-2;O00429;O00429-8;O00429-6;F8VZ52 O00429-4 DNM1L Dynamin-1-like protein 0 77.923 0.014463 4854500.0 30306.0 26838.0 30596.0 53637.0 44921.0 33341.0 28926.0 34570.0 38028.0 47458.0 False True 39942.6775960402 35512.858654305375 30190.277048928754 41271.81833338922 38684.49454290184 31256.181999355453 31500.357962912916 29228.00083957132 40038.08244429929 45796.50986509094 0.8721773277855632 0.7754490191265769 0.6592265903638594 0.9012000795468754 0.8447039885104796 0.6825013978451867 0.6878331570617027 0.6382145915850848 0.8742605618254525 1.0 15.482950034810843 -8.524424681885133 21.33936817798979 1.0000000051713753 0.7577283384698662 0.4385621232466558 0.08723076117171014 18.616490662766125 256986.66791277129 0.08869832819547226 0.02290180958712438 2.989340032393329e-09 8.524424681885133 -0.24227166670150913 EVDPDGRR ddPTM_PC-9_Lapatinib_30min_R1 1 EVDPDGRR 8 1 O00429-4;O00429-5;O00429-3;O00429-9;O00429-2;O00429;O00429-8;O00429-6;F8VZ52 O00429-4 DNM1L Dynamin-1-like protein 0 69.19800000000001 0.026274000000000002 4157600.0 34939.0 28069.0 26770.0 29073.0 38461.0 27189.0 29057.0 33118.0 38280.0 25824.0 False True 34440.76345297211 28004.007955054225 24569.07393518833 31211.125404684914 36198.799597235324 26026.18985065464 30561.42928300706 34656.783183203064 33968.503293729525 30287.643991682962 1.1371225659688025 0.9246017274484662 0.8111913208546376 1.030490368060835 1.1951672308079022 0.8593005734550193 1.0090395044064595 1.1442548384654772 1.121530063647649 1.0 14.886441738015774 -7.6443574214619865 6.439637232621219 1.0987296185347033 0.9879624700747797 0.12043010972951995 0.1145558224363071 0.41781603644589044 21.803782592655185 0.05662782776466188 0.032252489985458176 2.267997536749418e-08 7.6443574214619865 -0.11076714845992364 EVDYS(ph)DSLTEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVDYSDSLTEK 11 0 P51532;A0A2R8Y7Y7;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8YG32;A0A2R8Y440;A0A2R8Y7F3;K7EP28;A0A2R8YF80;A0A2R8Y6N0;A0A2R8Y526;A0A2R8YF58;A0A2R8Y4C5;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8Y523;A0A2R8Y5K3;K7EQF0;A0A2R8YFK5;A0A0A0MT49;P51532-5;P51532-2;P51532-3;P51532-4 P51532 SMARCA4 Transcription activator BRG1 1 EVDY(0.03)S(0.592)DS(0.37)LT(0.008)EK 71.268 0.030151999999999998 4893700.0 18577.0 15805.0 13654.0 20279.0 13289.0 16107.0 21678.0 13242.0 16669.0 15623.0 True False 21721.719187525232 17374.01594839388 13979.563143083351 19142.833375405058 10685.115845884697 15262.320565247028 19624.502904871235 12894.411531058757 16912.75259035021 18455.326228400052 1.1769891747618462 0.9414093109694158 0.7574812262906978 1.0372525057805282 0.5789719300351279 0.8269873085072073 1.0633517209071055 0.6986823950701093 0.9164158021939462 1.0 14.171749619378172 -4.816970015247764 3.206766092030554 0.8510904947398547 1.2109673276832247 0.29678977304029563 0.14608059409081808 0.36563641217964116 5.974992543869861 0.03575709297412759 0.31745524034259454 1.5241579817560149e-05 4.816970015247764 0.35987683294337003 EVDYSDS(ph)LTEK ddPTM_PC-9_AZD4547_30min_R2 4 EVDYSDSLTEK 11 0 P51532;A0A2R8Y7Y7;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8YG32;A0A2R8Y440;A0A2R8Y7F3;K7EP28;A0A2R8YF80;A0A2R8Y6N0;A0A2R8Y526;A0A2R8YF58;A0A2R8Y4C5;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8Y523;A0A2R8Y5K3;K7EQF0;A0A2R8YFK5;A0A0A0MT49;P51532-5;P51532-2;P51532-3;P51532-4 P51532 SMARCA4 Transcription activator BRG1 1 EVDYS(0.499)DS(0.5)LTEK;EVDYS(0.14)DS(0.812)LT(0.049)EK;EVDYS(0.042)DS(0.917)LT(0.042)EK;EVDYS(0.01)DS(0.952)LT(0.038)EK 187.62 0.00011464 57520600.0 68380.8 72341.4 79686.5 75170.4 66050.5 75791.2 77508.8 89228.4 79952.6 70640.4 True False 90124.47199100215 95724.34283681965 78629.80494376579 57841.02565110279 56880.52818962043 71051.96428270146 84406.93304555847 75440.20104465162 84178.73120953211 68167.30109726441 1.322107088593814 1.4042560185892574 1.1534827355358102 0.8485157065052702 0.8344254103365562 1.0423174034911706 1.2382319922732832 1.1066919157765962 1.234884319234259 1.0 16.056792244055558 -5.42049792917147 4.430482631774088 1.0444294855209943 1.3584222542036237 0.48716761074845616 0.1292582595650356 0.20706825748826477 6.716762568177559 0.03894990251417936 0.08443488375285331 3.7975374973121423e-06 5.42049792917147 0.3139927686826294 EVDYSDS(ph)LTEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EVDYSDSLTEK 11 0 P51532;A0A2R8Y7Y7;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8YG32;A0A2R8Y440;A0A2R8Y7F3;K7EP28;A0A2R8YF80;A0A2R8Y6N0;A0A2R8Y526;A0A2R8YF58;A0A2R8Y4C5;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8Y523;A0A2R8Y5K3;K7EQF0;A0A2R8YFK5;A0A0A0MT49;P51532-5;P51532-2;P51532-3;P51532-4 P51532 SMARCA4 Transcription activator BRG1 1 EVDY(0.002)S(0.108)DS(0.879)LT(0.012)EK;EVDYS(0.28)DS(0.718)LT(0.002)EK;EVDYS(0.018)DS(0.608)LT(0.374)EK 190.85 0.00044482 29322800.0 93953.0 100690.0 77408.0 87472.0 88851.0 72563.0 86282.0 75503.0 70536.0 63035.0 True False 109857.38724366477 110685.83776297263 79253.70029147466 82571.22742805016 71441.28437224035 68757.6685401391 78108.74433241549 73521.12625204104 71567.45555899845 74462.74651521455 1.4753335377069154 1.4864592422783764 1.064340277527652 1.1088931216253064 0.9594231708555521 0.9233834602929969 1.0489640523326114 0.987354478484337 0.9611175911215615 1.0 16.18423120969004 -5.309516401898788 2.8209836201624574 0.9973420252494819 1.5014682950190066 0.9331115026050038 0.050884095710195816 0.06269758603741984 0.972177098549731 0.01463632834783605 0.041375305743033566 4.903245044705772e-06 5.309516401898788 0.5041262697695247 EVDYSDS(ph)LTEK ddPTM_PC-9_Lapatinib_30min_R1 4 EVDYSDSLTEK 11 0 P51532;A0A2R8Y7Y7;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8YG32;A0A2R8Y440;A0A2R8Y7F3;K7EP28;A0A2R8YF80;A0A2R8Y6N0;A0A2R8Y526;A0A2R8YF58;A0A2R8Y4C5;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8Y523;A0A2R8Y5K3;K7EQF0;A0A2R8YFK5;A0A0A0MT49;P51532-5;P51532-2;P51532-3;P51532-4 P51532 SMARCA4 Transcription activator BRG1 1 EVDYS(0.223)DS(0.755)LT(0.023)EK;EVDYS(0.196)DS(0.804)LTEK;EVDYS(0.011)DS(0.85)LT(0.139)EK;EVDYS(0.056)DS(0.643)LT(0.301)EK 198.52 5.7041000000000005e-05 58051200.0 127351.0 116812.5 117074.7 108446.0 109924.9 112898.2 112763.5 110717.5 109134.0 98279.9 True False 125534.9513866869 116542.02783318848 107449.270087411 116421.48060525105 103459.3335026685 108069.8071645583 118601.84227395701 115861.83924410577 96842.17968803238 115267.44976526515 1.0890754644292977 1.011057571504522 0.9321735694354705 1.0100117669154303 0.8975589701460115 0.9375570239875664 1.028927442356729 1.0051566116891721 0.8401520106955201 1.0 16.814625644043105 -4.884127631406686 2.6857084709111856 0.958361356708655 1.1006642879469422 0.35579233744576977 0.055258108099950576 0.41187786506957386 4.6959355193522985 0.014218110961658478 0.11980989730333858 1.3057870841903858e-05 4.884127631406686 0.1423029312382872 EVEDKES(ph)EGEEEDEDEDLSK ddPTM_PC-9_AZD4547_30min_R2 3 EVEDKESEGEEEDEDEDLSK 20 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 EVEDKES(1)EGEEEDEDEDLSK;EVEDKES(1)EGEEEDEDEDLSK;EVEDKES(1)EGEEEDEDEDLSK 82.609 0.00049141 90699000.0 90502.0 98195.0 69282.0 56036.0 80286.0 88146.0 92995.0 72860.0 87277.0 81422.0 True False 119279.75344145834 129934.61344211632 68363.27541194532 43117.76594756977 69139.6747372369 82634.21668561775 101271.3748448138 61601.161156238515 91890.28404047314 78571.44056292802 1.5181057211993834 1.6537130096024066 0.8700779179069911 0.5487714828524325 0.8799593623571506 1.0517080518516884 1.2889082104038216 0.7840146586965275 1.1695125274797276 1.0 16.261717391199284 -5.261301853099307 24.999993487700102 0.9404363611067507 1.5859094155026001 0.6270621135245751 0.1963439227447313 7.671306140861699 1394168.0004394064 0.05432898469729255 0.12646247216908815 5.478960215589034e-06 5.261301853099307 0.6454730543958495 EVEDKES(ph)EGEEEDEDEDLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVEDKESEGEEEDEDEDLSK 20 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 EVEDKES(1)EGEEEDEDEDLSK 76.57300000000001 0.0073139 0.0 16769.0 16941.0 10320.0 13989.0 13595.0 9179.0 16489.0 13765.0 13135.0 8986.5 True False 19607.660497152967 18622.79052083143 10566.067938817941 13205.24168294991 10931.157342524073 8697.637081294004 14927.042549977958 13403.683335223068 13327.074526021359 10615.681312905148 1.8470468281029269 1.75427181467781 0.995326406979937 1.2439372748404491 1.0297179258042921 0.8193197238052504 1.4061313739544559 1.2626305312056263 1.2554139610257569 1.0 13.373909345725083 -5.232117196205272 8.932872495239293 1.1357087760016091 1.80290728026161 0.7297481796694958 0.16401738626634704 0.19693304248530819 56.200994661899514 0.04362899204632907 0.11346267470636685 5.859800139876678e-06 5.232117196205272 0.6671985042600008 EVEDKES(ph)EGEEEDEDEDLSK ddPTM_PC-9_Lapatinib_30min_R1 4 EVEDKESEGEEEDEDEDLSK 20 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 EVEDKES(1)EGEEEDEDEDLSK;EVEDKES(0.999)EGEEEDEDEDLS(0.001)K;EVEDKES(0.991)EGEEEDEDEDLS(0.009)K;EVEDKES(1)EGEEEDEDEDLSK 71.842 0.0016804000000000003 292563000.0 95134.0 144507.0 90774.0 120239.0 129634.0 121778.0 129735.0 131619.0 104035.0 134959.0 True False 93777.37171456113 144172.40291998337 83310.91211777307 129081.77716554582 122009.18299024993 116569.83881838304 136452.04350176975 137734.49923878242 92317.48276288259 158286.48332843665 0.5924534410179403 0.9108320551972384 0.526329920065929 0.8154946300607835 0.7708123929766441 0.7364484722078661 0.8620574583026049 0.8701595761211658 0.5832303606829673 1.0 17.27217853807604 -14.522878745280336 0.20228878324152033 2.1003262633497854 0.7130171176714346 0.2590595827942559 0.12770709119934026 197.674617006357 1.9542875549404424 88.60060451053718 0.28235664478843975 3.0000000000000132e-15 14.522878745280336 -1.3873091456783508 EVEDKES(ph)EGEEEDEDEDLSKYK ddPTM_PC-9_Lapatinib_30min_R1 1 EVEDKESEGEEEDEDEDLSKYK 22 2 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 EVEDKES(0.998)EGEEEDEDEDLS(0.001)KY(0.001)K 48.288000000000004 0.015594 7798900.0 32460.0 27688.0 18933.0 28690.0 30700.0 25443.0 24209.0 19177.0 24007.0 27116.0 True False 31997.114447565036 27623.89013714565 17376.401823493485 30799.95830703438 28894.286358522266 24354.862200529828 25462.423564453256 20068.033429080406 21303.078855082662 31802.964470201143 1.00610477609865 0.868594818040588 0.5463767957787359 0.9684618657450451 0.9085406609058643 0.7658047797195112 0.8006305068922468 0.6310114092629265 0.6698456955182055 1.0 14.95687363018872 -6.899809970669599 7.035088726611819 0.750020432065482 0.8485769973614441 0.06546939902668181 0.14838367526221447 0.6000729174845207 36.71264733115969 0.05340529723979461 0.04709329399494986 1.259476386098055e-07 6.899809970669599 0.09855656529596213 EVEEDEYK ddPTM_PC-9_AZD4547_30min_R2 2 EVEEDEYK 8 0 P14625 P14625 HSP90B1 Endoplasmin 0 ; 114.28 0.016975 28856000.0 121844.0 113613.0 115798.0 128136.0 128188.0 110507.0 106427.0 108949.0 114285.0 103206.0 False True 160587.85748735987 150336.18042669352 114262.44285893087 98596.22488146549 110391.30888594432 103596.9798207243 115898.7968235817 92113.4354489574 120325.87178254817 99592.78935346178 1.6124446210400065 1.5095086843399868 1.1472963414389918 0.9899936081872412 1.108426720474289 1.0402056262632766 1.1637267876115887 0.9249006483997589 1.2081785495082704 1.0 16.603753672640195 -5.2535506429218435 2.8867112645675035 1.0635828815713835 1.5979196950423258 0.8612018662754088 0.0794731003199486 0.08103059449701665 1.3371742908656519 0.019648013753567402 0.060299790764623336 5.5776255785952965e-06 5.2535506429218435 0.5343368134709423 EVEEDEYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EVEEDEYK 8 0 P14625 P14625 HSP90B1 Endoplasmin 0 ; 123.72 0.01514 18269500.0 93167.0 103633.0 92060.0 107454.0 91166.0 80680.0 109020.0 72044.0 69714.0 72927.0 False True 108938.33296787206 113920.99935336309 94255.05953949426 101433.70075056843 73302.67674060688 76448.99877097727 98692.83636355143 70152.92133692792 70733.43536406968 86148.0878101855 1.2645473130860603 1.3223856994292325 1.0941050687877283 1.1774341523872531 0.8508915125558959 0.8874137629081363 1.1456184213978888 0.8143294078854013 0.8210679675203039 1.0 16.39453115351123 -5.835462478709475 1.272617840840663 0.9189219088186371 1.2924756122497894 0.6352176563712332 0.10847777632556144 0.30812252349527125 1.0016007902573818 0.03921343176626862 0.09025141674241458 1.4606209357446814e-06 5.835462478709475 0.37355370343115224 EVEEDEYK ddPTM_PC-9_Lapatinib_30min_R1 2 EVEEDEYK 8 0 P14625 P14625 HSP90B1 Endoplasmin 0 ; 137.0 0.015269999999999999 38148000.0 173794.0 162595.0 160004.0 122680.0 147826.0 124690.0 164906.0 132800.0 123773.0 115731.0 False True 171315.66569008338 162218.52126730717 146849.08875330142 131702.2964484829 139131.165317098 119357.29936658675 173444.02578874494 138970.37281023542 109832.38135252827 135734.9491481358 1.2621337891622604 1.1951124031458413 1.0818811932734882 0.9702902404652479 1.0250209411082158 0.8793409517273615 1.2778140550924355 1.0238363345800394 0.8091680296182342 1.0 17.05043270934926 -5.276663953764375 2.07417972851376 1.0066877845947206 1.2567767597123833 0.39021435502310364 0.11481975910892293 0.3957393579771398 3.110952782236006 0.03299382836729369 0.12367043103581525 5.288543077659763e-06 5.276663953764375 0.2500889751176627 EVEEELATSGGQS(ph)PTGEQIPQFQQR ddPTM_PC-9_AZD4547_30min_R2 1 EVEEELATSGGQSPTGEQIPQFQQR 25 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 EVEEELAT(0.025)S(0.234)GGQS(0.607)PT(0.134)GEQIPQFQQR 85.525 5.7215999999999996e-06 3472900.0 5920.8 3610.8 6579.6 9284.5 7700.8 5580.7 4955.6 7110.2 7113.1 8280.9 True False 7803.491239709461 4777.920486957514 6492.350204965731 7144.101969095072 6631.6768454838175 5231.73794678633 5396.638799730736 6011.481966141743 7489.083944318539 7990.988211509794 0.976536447453361 0.5979135947260755 0.8124589891916616 0.8940198358452196 0.8298944598531509 0.6547047509406675 0.6753406033008164 0.7522826723086795 0.9371912141644334 1.0 12.964158210804891 -8.372763574137252 3.7724491851349216 0.995158419907355 0.7680989855033754 0.34670517659156663 0.10781887930796996 0.25245031594573836 6.02855354686865 0.10341297916409802 0.027487211425567953 4.238736561135285e-09 8.372763574137252 -0.22705943440397958 EVEEELATSGGQS(ph)PTGEQIPQFQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVEEELATSGGQSPTGEQIPQFQQR 25 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 EVEEELAT(0.005)S(0.067)GGQS(0.921)PT(0.007)GEQIPQFQQR 103.04 5.4023e-07 2565300.0 5676.5 5819.9 5231.4 6733.2 8863.3 5432.8 6002.8 5994.9 6546.3 4806.6 True False 6637.419334014475 6397.661209620847 5356.136416194981 6355.960633328932 7126.599990731417 5147.894404102198 5434.1713274915155 5837.540227121592 6642.027253117136 5677.998530975333 1.1689716539737003 1.126745837414279 0.9433141602583219 1.1194015987596853 1.25512536712602 0.9066389108800849 0.9570575437535497 1.0280982277955704 1.169783193300018 1.0 12.471166760467105 -6.775154626130915 24.999954667012677 1.0106181291983145 1.1127854475528458 0.2460466936021951 0.09581702413373272 405.6496345460737 739407.6979929104 0.0357064258338377 0.03165314824618818 1.6782064034289923e-07 6.775154626130915 0.1021673183545313 EVEEELATSGGQS(ph)PTGEQIPQFQQR ddPTM_PC-9_Lapatinib_30min_R1 2 EVEEELATSGGQSPTGEQIPQFQQR 25 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 EVEEELATS(0.027)GGQS(0.965)PT(0.007)GEQIPQFQQR;EVEEELAT(0.005)S(0.023)GGQS(0.883)PT(0.089)GEQIPQFQQR 134.07 2.3194000000000002e-07 5819900.0 21078.7 15080.400000000001 20994.7 16839.9 18098.800000000003 18761.4 16107.8 14889.699999999999 20471.9 11145.5 True False 20778.113872639846 15045.482260337023 19268.596807885635 18078.36242225961 17034.26416760988 17959.0186569595 16941.783067929286 15581.529819522279 18166.13904333597 13071.984824554758 1.5895148404402746 1.1509715213312668 1.4740375747446552 1.3829852669581395 1.3031122967349436 1.373855531351659 1.2960375409941876 1.191978879156402 1.3897001325469884 1.0 13.674190593302331 -13.837232797613423 0.16033527651944127 1.4682915118463073e-12 1.4393976360019223 0.47878707796335995 0.11553070755014008 88.98149900461173 0.9978639672193372 28.92932159649457 0.4691837708094886 1.4546791107254812e-14 13.837232797613423 1.439397636000454 EVEELILTESK ddPTM_PC-9_Lapatinib_30min_R1 1 EVEELILTESK 11 0 H0YER7;G3V1C3;Q9BZZ5-1;Q9BZZ5-5;Q9BZZ5-2;Q9BZZ5-6;Q9BZZ5;Q9BZZ5-3 H0YER7 API5 Apoptosis inhibitor 5 0 121.61 0.0034606000000000003 1621100.0 12233.0 11117.0 11289.0 10589.0 13725.0 14134.0 11283.0 9636.1 14399.0 12155.0 False True 12058.555176742548 11091.25926952645 10360.861996800191 11367.750383868484 12917.722484388221 13529.52176796324 11867.178531856993 10083.828384312548 12777.232991808018 14255.975554480574 0.8458596979673279 0.7780077362745287 0.7267732718259208 0.7974024885512422 0.906126868345271 0.9490421554287098 0.8324353872876279 0.7073404654613943 0.8962720890603804 1.0 13.799279147654085 -6.122763363937059 5.91317210987279 0.8677988810239738 0.7798631282828234 0.2525322733435401 0.0778314171771 0.3882494900472098 17.16532941415441 0.024184121183162207 0.031506566637595906 7.537661599502279e-07 6.122763363937059 -0.0879357527411504 EVELVS(ph)E ddPTM_PC-9_AZD4547_30min_R2 2 EVELVSE 7 0 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 EVELVS(1)E;EVELVS(1)E 116.25 0.010582 290681300.0 134309.0 143901.0 167248.0 230280.0 204200.0 181914.0 152671.0 187668.0 163547.0 175229.0 True False 177016.4681992534 190414.18411257138 165030.18224209818 177192.50379053425 175850.35474857135 170538.88882249282 166258.42323708345 158668.22278162208 172191.76053218194 169094.28604555625 1.0468506792214305 1.1260829006443853 0.975965457505979 1.047891729131499 1.039954447078093 1.0085431791382198 0.9832291032725448 0.9383417174656911 1.018318031667795 1.0 17.36746838413729 -5.87978967961916 0.5542673764769156 0.9798841747044746 1.0907077534854248 0.37084116938146106 0.038551251857041974 1.465235582943403 0.7619056388748363 0.026815650664043553 0.09181517209735189 1.3188952992948073e-06 5.87978967961916 0.11082357878095017 EVELVS(ph)E ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EVELVSE 7 0 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 EVELVS(1)E;EVELVS(1)E 95.90899999999999 0.012975 9809100.0 125508.0 139049.0 147404.0 163857.0 171358.0 149459.0 170434.0 149450.0 153266.0 126179.0 True False 146754.025504006 152852.86577717285 150918.67039278283 154676.6235215613 137781.63000369543 141621.1069324678 154289.25768469507 145527.0958553643 155507.22529921468 149054.2538675852 0.9845678449028186 1.0254847601529185 1.01250830806113 1.037720289814545 0.9243723438184864 0.9501312660172667 1.0351214653810583 0.9763364149583124 1.04329276933862 1.0 17.185478023506896 -10.689859686029871 3.8343988983919384 1.000001311424842 0.9979494480835631 0.0 0.037862922009281035 428731104473.57196 93157558044.24506 5198488.779518305 0.009393572955426683 2.0423977058529692e-11 10.689859686029871 -0.0020518633412789367 EVELVS(ph)E ddPTM_PC-9_Lapatinib_30min_R1 1 EVELVSE 7 0 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 EVELVS(1)E 89.75200000000001 0.016388 7968900.0 116840.0 112670.0 106710.0 95846.0 123110.0 110420.0 100590.0 99928.0 109490.0 92320.0 True False 115173.84017416833 112409.11953742424 97936.71571251178 102894.8345728833 115868.91184357251 105697.59400159186 105798.05800934986 104571.01968509947 97158.08321918605 108277.38899133238 1.0636924407494535 1.0381587567319581 0.9044983133122246 0.9502892111770449 1.0701118019464602 0.9761742039240803 0.9771020431405029 0.9657696833959525 0.8973072229047153 1.0 16.724372478270837 -7.581965621918066 1.9773429724995735 0.9471873241687745 0.9985819540152704 0.13457556160537554 0.05292648237688599 0.7414692282815009 5.735111807095235 0.034995094813682535 0.01693005385435691 2.6183902677543276e-08 7.581965621918066 0.0513946298464959 EVENSEDPK ddPTM_PC-9_Lapatinib_30min_R1 2 EVENSEDPK 9 0 P18206;P18206-2 P18206 VCL Vinculin 0 ; 116.52 0.008817100000000001 5873900.0 59412.0 67309.0 66115.0 59587.0 66308.0 57158.0 62840.0 56132.0 64487.0 59266.0 False True 58564.77398517357 67153.15014595274 60679.279911280406 63969.22675640492 62407.893806543834 54713.48558180579 66093.54772151857 58740.09763994069 57223.794981785126 69510.04913301897 0.8425367945446304 0.9660926870795916 0.8729569417388926 0.9202874628097187 0.8978254883278246 0.7871305841994514 0.9508488131699869 0.8450590723584702 0.8232449220727486 1.0 16.084933944239385 -4.468384879226148 16.917524061250102 0.8903847794281965 0.44288725751451374 0.0542810474211608 0.06315057919473742 5894776.543074505 43446811.328279875 0.015005244436287854 89592930.16555405 3.4010664775447134e-05 4.468384879226148 -0.44749752191368275 EVEQLIK ddPTM_PC-9_Lapatinib_30min_R1 1 EVEQLIK 7 0 P25789;H0YN18;P25789-2 P25789 PSMA4 Proteasome subunit alpha type-4 0 92.47 0.02502 0.0 40855.0 30624.0 51438.0 36071.0 41421.0 39409.0 30253.0 44647.0 43789.0 29164.0 False True 40272.400208110565 30553.092009532946 47208.966196422 38723.78166932858 38984.698216819226 37723.56893686596 31819.352310934144 46721.46261188682 38857.02170138772 34204.958541412685 1.1773848566239862 0.8932357562293681 1.3801790210990925 1.1321101770214064 1.1397382098744429 1.1028684303532545 0.9302555438682892 1.3659265967336323 1.1360055196191126 1.0 15.061917860934413 -10.68042085519198 5.105108537356171 0.9999930646747472 1.1387478255720458 0.07505780613148838 0.1471316195160396 1.1307053448887415e-05 1.865807148931584e-06 0.13859277728992336 0.033612004628807805 2.0872724688970565e-11 10.68042085519198 0.13875476089729855 EVERVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVERVLK 7 1 A0A096LP73;A0A096LNH5;H7C1F6;A0A2R8YDR7;H7C2G3;F2Z2Q0;A0A096LP12;P0DPI2;A0A0B4J2D5;A0A096LPI6 A0A096LP73 C21orf33 0 81.635 0.030663 2825600.0 34159.0 28080.0 33441.0 41039.0 57779.0 42809.0 41011.0 48340.0 44627.0 32313.0 False True 39941.44402899684 30867.596825745004 34238.36026569874 38739.71788023315 46457.619720021976 40564.02067906255 37126.14118607229 47071.126220463724 45279.58544901067 38171.09111043272 1.0463794161252116 0.8086642516044934 0.8969709607368519 1.0148967910860953 1.2170891208117556 1.062689577348126 0.9726245728387148 1.2331616637387266 1.1862271717099304 1.0 15.220192805744313 -5.967486071480184 4.213926146561741 1.1148949000227473 0.9089946525300472 0.44386674823343175 0.09757654214041304 0.18569299071716258 7.4653781409847895 0.02880148806205622 0.042595189199863034 1.077739817982659e-06 5.967486071480184 -0.20590024749270008 EVESPYEVHDYIR ddPTM_PC-9_AZD4547_30min_R2 1 EVESPYEVHDYIR 13 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 0 84.734 0.0070843 3076600.0 14131.0 11571.0 14708.0 23712.0 21952.0 16176.0 14342.0 21573.0 15954.0 17337.0 False True 18624.36405694068 15311.099466762327 14512.962309963514 18245.564746748063 18904.343719102024 15164.512162849758 15618.410215864516 18239.38854822308 16797.29586926347 16730.03690697211 1.113229107652424 0.9151862337124641 0.8674793959310008 1.090587238283041 1.1299642567568868 0.9064243101896606 0.9335550365316689 1.0902180700284028 1.0040202518778265 1.0 14.030153007558525 -5.775787641608268 24.999954331088414 1.0218528614355815 0.9602869984332648 0.08003140164002565 0.08777285526671266 606.4331657536652 1056628.5562284954 0.025909590445956643 0.038628459949493626 1.6757620785846115e-06 5.775787641608268 -0.0615658630023167 EVFEDAAEIR ddPTM_PC-9_AZD4547_30min_R2 3 EVFEDAAEIR 10 0 P19338;H7BY16 P19338 NCL Nucleolin 0 ;; 162.88 0.00055111 35531500.0 78787.0 73618.0 104312.0 124507.0 113905.0 97042.0 88923.0 115378.0 81490.0 94468.0 False True 103839.62712859557 97413.57882154612 102928.75472374995 95803.8347639743 98091.25689341806 90973.94839931156 96836.974733323 97548.98122268036 85797.39503486767 91160.7040738214 1.1390832067785135 1.0685917776881273 1.1290912654689333 1.0509334667533166 1.0760256613856816 0.9979513576994907 1.062266639087221 1.0700770931265051 0.9411664368606615 1.0 16.476124446757836 -5.736200385049865 0.2926698278951843 0.9865894978188077 1.1781200221383359 0.5458623338514075 0.03853529981638925 3.743779764212763 0.4105348665015585 0.048325929723321004 0.24771850268272613 1.8356911533558174e-06 5.736200385049865 0.19153052431952822 EVFEDAAEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EVFEDAAEIR 10 0 P19338;H7BY16 P19338 NCL Nucleolin 0 ;;; 148.94 0.00053632 33220300.0 70829.0 75077.0 79787.0 85737.0 102310.0 93511.0 89922.0 87720.0 80834.0 67879.0 False True 82818.95076348312 82530.1483933923 81689.42467388255 80933.4338531045 82263.08993848022 88607.11854329258 81403.93718109751 85417.44294702251 82016.04432709633 80184.92537013176 1.0328493838610282 1.0292476798155643 1.0187628696641675 1.0093347780710358 1.025917147877306 1.1050346200895513 1.0152025060239043 1.0652556269490503 1.0228361995538708 1.0 16.291043417502358 -6.552186801472328 24.999670189118145 1.046466475183489 1.0221153372233194 0.08683242494473564 0.027962279291085294 390.6836971584946 333248.8952102013 0.008752527953952956 0.008752574099509644 2.804227206679214e-07 6.552186801472328 -0.024351137960169522 EVFEDAAEIR ddPTM_PC-9_Lapatinib_30min_R1 2 EVFEDAAEIR 10 0 P19338;H7BY16 P19338 NCL Nucleolin 0 ; 150.27 0.00073724 48732000.0 68355.0 65598.0 66105.0 59390.0 62562.0 73132.0 64627.0 53809.0 59842.0 56406.0 False True 67380.24516522815 65446.111861329184 60670.10207267934 63757.73871923214 58882.226161624414 70004.31483901847 67973.06983766032 56309.162579412216 53101.96379580355 66155.7019437295 1.0185100178143407 0.9892739391835964 0.9170804675957324 0.963752735530839 0.8900551945123077 1.0581750745923988 1.0274710696211287 0.8511611384201997 0.8026815865542603 1.0 16.013577886944198 -7.771815852365092 24.996891664931606 0.8701909888326604 0.9773574209278222 0.297334984126029 0.06639919905617693 246.07339034039612 592780.4185637418 0.035875156696604765 0.017529095086749054 1.691157856950566e-08 7.771815852365092 0.10716643209516175 EVFEFRPELVNDDDEEADDTR ddPTM_PC-9_AZD4547_30min_R2 3 EVFEFRPELVNDDDEEADDTR 21 1 Q8WU90;Q8WU90-2 Q8WU90 ZC3H15 Zinc finger CCCH domain-containing protein 15 0 ;; 131.37 8.822499999999999e-07 3531800.0 9187.61 8482.14 14611.7 14871.3 12993.9 12799.099999999999 12008.8 13413.4 12919.8 13456.0 False True 12109.078865840265 11223.82587771181 14417.93931088482 11442.951544294636 11189.92127604044 11998.770253680166 13077.55993587183 11340.66723926832 13602.714251705534 12984.909535687635 0.9325501138502165 0.8643745916646031 1.1103611674196616 0.8812500012298821 0.8617635144308198 0.9240549747923025 1.0071352364781252 0.873372833911527 1.0475786692483247 1.0 13.664548342516909 -8.27669752027858 24.584851008891235 1.0237893497358312 0.9337842247077882 0.19931552150631526 0.07362193966093403 1238.5158861676357 1995549.0040477864 0.0691009575542627 0.018132436275406345 5.288134343255454e-09 8.27669752027858 -0.09000512502804303 EVFEFRPELVNDDDEEADDTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVFEFRPELVNDDDEEADDTR 21 1 Q8WU90;Q8WU90-2 Q8WU90 ZC3H15 Zinc finger CCCH domain-containing protein 15 0 126.8 1.5845e-05 1186100.0 3535.4 4099.2 3747.8 3617.1 7535.1 4002.5 4398.1 1704.9 1883.4 1805.4 False True 4133.873392667098 4506.141485330983 3837.1617656106478 3414.4456137964235 6058.65124616794 3792.6018540014416 3981.4801285134363 1660.1481814908682 1910.9411619572625 2132.7047284614628 1.9383242966077552 2.1128763983102914 1.7991997271834173 1.6009931277545444 2.8408298463982224 1.7783061121346282 1.8668688990930702 0.7784238292979743 0.8960176889258453 1.0 11.058468524005928 -7.713540201581448 5.022608376017194 0.873268166043893 2.0079346749496234 0.7166154111771389 0.3173114992563748 0.10188583522736942 5.591942091337627 0.1618354023808166 0.08776693760371475 1.9340148232956084e-08 7.713540201581448 1.1346665089057304 EVFEFRPELVNDDDEEADDTR ddPTM_PC-9_Lapatinib_30min_R1 1 EVFEFRPELVNDDDEEADDTR 21 1 Q8WU90;Q8WU90-2 Q8WU90 ZC3H15 Zinc finger CCCH domain-containing protein 15 0 150.45 3.7478e-16 0.0 4540.6 8025.9 9474.6 6964.9 7185.0 9483.7 7059.7 7727.0 5812.1 6391.7 False True 4475.85021135594 8007.31652165983 8695.63496101365 7477.121980225291 6762.392426253506 9078.104258584475 7425.216722622608 8086.024628800355 5157.480093873703 7496.4968285951045 0.5970589081399965 1.0681411204119 1.159959799868717 0.9974154796816682 0.9020736726598235 1.2109795369960525 0.9904915445704451 1.0786404388189053 0.6879853632700396 1.0 12.872000855108206 -4.757428379866774 24.99851139529628 1.0195819310459142 0.5970582952132812 0.4494656714828673 0.13699286695791382 106.34675666919273 662714.398194868 0.03321718487128264 0.246734290279925 1.748121523906006e-05 4.757428379866774 -0.42252363583263297 EVGS(ph)PPLDPTER ddPTM_PC-9_AZD4547_30min_R2 1 EVGSPPLDPTER 12 0 A0A1B0GV79;A0A1B0GW21;A0A1B0GTE6;A0A0D9SFK7;A0A1B0GUH6;A0A1B0GUA3;Q96EK5 A0A1B0GV79 KIF1BP;KIAA1279 KIF1-binding protein 1 EVGS(0.778)PPLDPT(0.222)ER 112.84 0.0018855999999999999 0.0 14369.0 13917.0 18658.0 23689.0 18512.0 15885.0 12757.0 23136.0 16893.0 18722.0 True False 18938.043106233148 18415.398088231905 18410.58272907938 18227.8670414016 15941.928340379756 14891.708438851898 13892.348286416365 19560.862812389983 17785.92949225697 18066.54847853329 1.048238025582771 1.0193091453031617 1.0190426107651316 1.0089291301578711 0.8824003300531914 0.824269696923364 0.7689541974729309 1.0827116665716334 0.984467482175151 1.0 14.141033292585025 -6.162640578643342 5.3100339449087 0.9154548752031695 1.0253835371324398 0.24971300121636242 0.08453088082335934 0.345587349983989 14.842710853848272 0.027556856774064036 0.0358820245537174 6.876372920162717e-07 6.162640578643342 0.10992866192927031 EVGS(ph)PPLDPTER ddPTM_PC-9_Lapatinib_30min_R1 1 EVGSPPLDPTER 12 0 A0A1B0GV79;A0A1B0GW21;A0A1B0GTE6;A0A0D9SFK7;A0A1B0GUH6;A0A1B0GUA3;Q96EK5 A0A1B0GV79 KIF1BP;KIAA1279 KIF1-binding protein 1 EVGS(1)PPLDPTER 114.76 0.0016820999999999997 0.0 18469.0 17519.0 16325.0 14833.0 16895.0 16348.0 19713.0 19402.0 18759.0 14203.0 True False 18205.628673200215 17478.435831864157 14982.82151632235 15923.86830143746 15901.269316848002 15648.834149049315 20733.64268355022 20303.487750483295 16646.16387897262 16657.9696256921 1.092908024344162 1.0492536740436016 0.8994386382608047 0.955930924311303 0.9545742773070605 0.9394202595323282 1.2446680567583748 1.2188452858725711 0.9992912853736224 1.0 14.023924946552256 -7.244030390170617 24.80485866797747 1.1339382725765113 0.9788079451591489 0.3350711196171997 0.09081988063994853 765.7820127383724 1091111.111698444 0.03547908703879145 0.02741530957358434 5.701243758878615e-08 7.244030390170617 -0.15513032741736232 EVGSIIGK ddPTM_PC-9_Lapatinib_30min_R1 2 EVGSIIGK 8 0 Q15366-2;Q15366;Q15366-6;Q15366-3;Q15366-5;H3BRU6;F8VZX2;Q15366-8;Q15366-4;P57721-5;P57721-3;P57721;P57721-4;J3QT27;E9PFP8;F8W1G6;F8VTZ0;P57721-2;Q15366-7;F8W0G4;C9JSA6;C9JTY5;C9J7A9;C9IZV9;C9J5V4;H3BSP4;C9K0A2;C9J0A4;C9JZY3;F8WC71;P57723-2;P57723;Q15365 Q15366-2;Q15365 PCBP2;PCBP3;PCBP4;PCBP1 Poly(rC)-binding protein 2;Poly(rC)-binding protein 3;Poly(rC)-binding protein 4;Poly(rC)-binding protein 1 0 ; 143.12 0.008498899999999998 21751000.0 154130.0 158756.0 161888.0 159113.0 147063.0 143468.0 144896.0 134748.0 157447.0 135607.0 False True 151932.0779360196 158388.41023593972 148578.19354575142 170814.7008054082 138413.0434769823 137332.2080802426 152398.0058984268 141008.884001759 139713.66086958788 159046.48926503066 0.9552683535368341 0.9958623479705087 0.9341809066792089 1.0739922748044273 0.8702678324847186 0.8634721125556943 0.9581978615351578 0.8865891014216963 0.878445425078028 1.0 17.279089001134544 -6.288804845397501 24.949591416978123 0.9039588025668193 0.9862825222797932 0.35799424860582885 0.05230097444598926 751.5126533727157 685165.4865772611 0.0155469814550844 0.017632434036011956 5.142746941848489e-07 6.288804845397501 0.08232371971297392 EVHDELEDLPSPPPPLS(ph)PPPTTSPHK ddPTM_PC-9_AZD4547_30min_R2 2 EVHDELEDLPSPPPPLSPPPTTSPHK 26 0 H0YJ30;G3V582;F5H039;Q9NQX3;Q9NQX3-2 H0YJ30 GPHN Gephyrin;Molybdopterin adenylyltransferase;Molybdopterin molybdenumtransferase 1 EVHDELEDLPSPPPPLS(0.901)PPPT(0.033)T(0.033)S(0.033)PHK;EVHDELEDLPS(0.004)PPPPLS(0.955)PPPT(0.014)T(0.014)S(0.014)PHK 80.41 2.8446e-05 7954500.0 20545.6 19630.8 37365.0 57586.0 49526.0 42012.0 32614.0 45345.0 34379.0 43256.0 True False 27078.67342497208 25976.072198782982 36869.51568614273 44310.437394831046 42650.1697809879 39384.98299861796 35516.58281831021 38337.972174439135 36196.203753880436 41741.62060610169 0.648721181204301 0.6223062694165223 0.8832794498820496 1.0615408973448877 1.021766025412856 0.9435422589428825 0.8508673669732526 0.9184591210824953 0.8671489805211194 1.0 15.349198993343764 -5.330670268856773 4.104562444142634 0.9480952683518657 0.6328228441666139 0.7974432288435358 0.06266405555291012 0.0964398570031659 3.1559088238000665 0.01848816010362088 0.042779592172765786 4.670138185230306e-06 5.330670268856773 -0.3152724241852518 EVHDELEDLPSPPPPLS(ph)PPPTTSPHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVHDELEDLPSPPPPLSPPPTTSPHK 26 0 H0YJ30;G3V582;F5H039;Q9NQX3;Q9NQX3-2 H0YJ30 GPHN Gephyrin;Molybdopterin adenylyltransferase;Molybdopterin molybdenumtransferase 1 EVHDELEDLPS(0.018)PPPPLS(0.933)PPPT(0.015)T(0.015)S(0.019)PHK 58.92 0.0026809 2143700.0 5669.6 8673.1 12227.0 11543.0 11050.0 9572.7 11081.0 10944.0 10306.0 6027.3 True False 6629.351300295688 9534.108049478953 12518.538051155723 10896.283132910927 8884.831823088718 9070.690760224763 10031.327460507351 10656.731596126492 10456.705752963548 7120.001777919453 0.9310884332718329 1.3390597849351844 1.758221197356749 1.5303764623630398 1.2478693264715686 1.2739731032588764 1.4088939544392391 1.4967315920025672 1.4686380817195692 1.0 12.797661886105903 -10.574888249455078 7.332060907923881 0.9999999557951171 1.394696506714209 0.2381889349761025 0.20513400140120994 1.553902112176614e-07 1.9874461268891944e-08 0.2080671005263622 0.050463679011914925 2.661409792729364e-11 10.574888249455078 0.39469655091909184 EVIEIEDAS(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 2 EVIEIEDASPTK 12 0 P46100-4;P46100;P46100-2;P46100-5;P46100-3 P46100-4 ATRX Transcriptional regulator ATRX 1 EVIEIEDAS(0.829)PT(0.171)K;EVIEIEDAS(0.834)PT(0.166)K 126.1 0.00027360000000000004 5492500.0 52426.0 54957.0 49981.0 45284.0 42369.0 54240.0 53269.0 63272.0 61149.0 50547.0 True False 69096.37747145796 72720.77550729032 49318.21928299472 34844.473430825725 36486.79569217535 50848.36422557928 58009.83780427327 53494.76624591718 64381.21130184226 48777.364915309416 1.416566425665425 1.4908713423439968 1.011088224397205 0.714357437949448 0.7480271998195518 1.0424582040023211 1.189277811644682 1.096712918764645 1.3198993306347178 1.0 15.573924201515023 -5.264907673523071 23.902369534563572 1.005582010924566 1.453718923547097 0.5088899177601875 0.17209664522398885 130.74794874097452 901088.6381335012 0.05069089259101567 0.11295585080488867 5.43365833123303e-06 5.264907673523071 0.4481369126225312 EVIEIEDAS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EVIEIEDASPTK 12 0 P46100-4;P46100;P46100-2;P46100-5;P46100-3 P46100-4 ATRX Transcriptional regulator ATRX 1 EVIEIEDAS(0.673)PT(0.327)K;EVIEIEDAS(0.844)PT(0.156)K 116.84 0.00065837 5806300.0 37170.0 77925.0 46813.0 44360.0 42838.0 31495.0 46221.0 37616.0 38914.0 31339.0 True False 43462.146859036045 85660.87901161624 47929.19945929113 41874.65301706045 34444.20141515606 29843.34675622122 41842.61226893874 36628.6198574465 39483.04363194482 37020.51262061248 1.1740017569296692 2.3138760905196523 1.2946660126095837 1.131120291234035 0.9304085485833612 0.8061300247799617 1.1302548048900163 0.9894141724296984 1.0665180149331925 1.0 15.176037251799945 -5.510415185165723 4.73128482392031 1.0102705785802761 1.7643718994308684 0.5350151228861626 0.2716716550514929 0.12351723077134787 7.368393505519127 0.06866837515259908 0.13625937749051265 3.0873425243482463e-06 5.510415185165723 0.7541013208505922 EVIEIEDAS(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 1 EVIEIEDASPTK 12 0 P46100-4;P46100;P46100-2;P46100-5;P46100-3 P46100-4 ATRX Transcriptional regulator ATRX 1 EVIEIEDAS(0.881)PT(0.119)K 102.33 0.0024411999999999997 2807000.0 32322.0 52066.0 36067.0 40928.0 52305.0 43739.0 51798.0 52843.0 43145.0 45510.0 True False 31861.082352871144 51945.44437592551 33101.71048264614 43937.98165180561 49228.52273558658 41868.38493058895 54479.846990439495 55298.27869285582 38285.555763008335 53376.34286173681 0.5969139256206137 0.973192271911213 0.6201569592055233 0.8231733254116 0.9222910393674868 0.7843996550876958 1.020674030282688 1.0360072595475018 0.7172757388452252 1.0 15.703912840593546 -6.339931202436107 1.2726139982028517 0.9302787344768157 0.7493828583616123 0.25704522741427005 0.13523150597535447 0.6619618017040771 2.194775401864261 0.05389754104219127 0.07175139226596343 4.5716060371666856e-07 6.339931202436107 -0.1808958761152034 EVIEIEDAS(ph)PTKCPITTK ddPTM_PC-9_AZD4547_30min_R2 3 EVIEIEDASPTKCPITTK 18 1 P46100-4;P46100;P46100-2;P46100-5;P46100-3 P46100-4 ATRX Transcriptional regulator ATRX 1 EVIEIEDAS(0.886)PT(0.112)KCPIT(0.001)T(0.001)K;EVIEIEDAS(0.995)PT(0.005)KCPITTK;EVIEIEDAS(0.88)PT(0.106)KCPIT(0.013)T(0.001)K 81.665 0.0014255999999999997 110388900.0 182005.0 166046.0 187935.0 197533.0 198356.0 213726.0 211769.0 222641.0 183363.0 203513.0 True False 239878.80406082244 219717.12229349362 185442.8591054526 151994.81870442742 170817.69327378855 200361.6794335574 230616.03074908798 188236.94923121197 193055.19383701615 196388.07181453652 1.2214530233147631 1.1187905673873535 0.9442674261834992 0.7739513774948976 0.8697966821279455 1.020233446880488 1.174287361845863 0.958494818407188 0.9830291221522464 1.0 17.58334778058323 -5.074685837376506 3.30736565011087 0.9636450261166832 1.2092291708521075 0.4291072630191577 0.0975517457511246 0.2616396057976483 5.347602590559072 0.029044374727100915 0.11026719008331197 8.42004015456121e-06 5.074685837376506 0.24558414473542423 EVIEIEDAS(ph)PTKCPITTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EVIEIEDASPTKCPITTK 18 1 P46100-4;P46100;P46100-2;P46100-5;P46100-3 P46100-4 ATRX Transcriptional regulator ATRX 1 EVIEIEDAS(0.959)PT(0.041)KCPITTK;EVIEIEDAS(0.996)PT(0.004)KCPITTK;EVIEIEDAS(0.995)PT(0.005)KCPITTK 90.96799999999999 0.00060662 67193000.0 226257.0 224633.0 195144.0 252525.0 260227.0 213319.0 251961.0 222475.0 188531.0 180341.0 True False 264557.84132055193 246933.0796922219 199796.9730477411 238376.84294709587 209237.38740515002 202132.1761133625 228093.43004032905 216635.26698174747 191287.90920939005 213035.39572142903 1.2418492261562726 1.15911761449782 0.9378581074339456 1.1189541631795499 0.9821719376565695 0.9488196805458382 1.0706832508649893 1.016897995979155 0.8979160883645994 1.0 17.700733627842425 -5.0840547806192715 4.084283577513181 1.0024343737086983 1.2280818081619818 0.6475487916913389 0.06125331682380172 0.128430216869424 3.8368952211055793 0.015578050499049666 0.05025508429353049 8.24034167228803e-06 5.0840547806192715 0.2256474344532835 EVIEIEDAS(ph)PTKCPITTK ddPTM_PC-9_Lapatinib_30min_R1 3 EVIEIEDASPTKCPITTK 18 1 P46100-4;P46100;P46100-2;P46100-5;P46100-3 P46100-4 ATRX Transcriptional regulator ATRX 1 EVIEIEDAS(0.848)PT(0.146)KCPIT(0.005)T(0.001)K;EVIEIEDAS(0.952)PT(0.044)KCPIT(0.002)T(0.002)K;EVIEIEDAS(0.952)PT(0.04)KCPIT(0.006)T(0.002)K 71.527 0.004215600000000001 96443500.0 214124.0 236402.0 230828.0 245936.0 267117.0 241805.0 228292.0 251899.0 236942.0 214845.0 True False 211070.55249446727 235854.62569349585 211850.21286184713 264022.9538584455 251405.7032322279 231463.56382498567 240111.8427186653 263603.1471425109 210255.0968501266 251980.6719870326 0.8376458036643752 0.9360028443198746 0.8407399313259604 1.0477904982808866 0.9977182029467947 0.9185766590736658 0.9528978584953608 1.0461244708327329 0.834409620357496 1.0 17.942953551424466 -5.745753773973746 24.999686521049888 0.9711612247282289 0.8779168534624546 0.3345056968012482 0.0641919453477851 292.0109482852348 465402.7122513323 0.01679095554728653 0.028958415856699674 1.7957514510119703e-06 5.745753773973746 -0.09324437126577423 EVIEIEDASPT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 EVIEIEDASPTK 12 0 P46100-4;P46100;P46100-2;P46100-5;P46100-3 P46100-4 ATRX Transcriptional regulator ATRX 1 EVIEIEDAS(0.089)PT(0.911)K 129.37 0.00043378 2128600.0 18664.0 28937.0 27524.0 26062.0 31978.0 26422.0 30676.0 33010.0 27511.0 28484.0 True False 18397.847937441577 28869.998154383975 25261.08296571249 27978.68642028336 30097.116911166955 25291.992652690296 32264.253181179254 34543.76510892967 24412.421476326857 33407.42144745573 0.5507114030449284 0.864179182454762 0.756151833072299 0.8374991306733787 0.9009111031961766 0.7570770672160483 0.9657810086278438 1.0340147072787769 0.7307484510507194 1.0 15.027881012071742 -3.8542695876882425 0.5468793634729876 0.9075209386014589 1.6416955773178271e-37 0.4509960100957954 0.10290732829902494 10.20518090802966 1.0818681873409808 0.052670583034118174 7.367942874953401 0.00013987188003073434 3.8542695876882425 -0.9075209386014589 EVIEIEDASPT(ph)KCPITTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVIEIEDASPTKCPITTK 18 1 P46100-4;P46100;P46100-2;P46100-5;P46100-3 P46100-4 ATRX Transcriptional regulator ATRX 1 EVIEIEDAS(0.225)PT(0.77)KCPIT(0.004)TK 73.208 0.0052433 12333000.0 87560.0 79476.0 67450.0 89885.0 86203.0 67150.0 92642.0 80148.0 60622.0 62849.0 True False 102382.17861117028 87365.85204141405 69058.26380554962 84849.03486110162 69312.14096341329 63628.535789180976 83866.27909000279 78044.19992382562 61508.48206444365 74243.02618758976 1.3790140821103032 1.1767549967678697 0.9301649912688122 1.1428552851107345 0.933584533425165 0.8570304721740577 1.1296182738847145 1.051199067864387 0.8284748780179063 1.0 16.17996789627638 -4.930471644267926 2.3974764557254375 0.9897899901242942 1.4127389915295039 0.6115467183777179 0.09962320577767539 0.27237109046427477 2.4660270358100207 0.026442808560447964 0.21238191740071308 1.1736223075342128e-05 4.930471644267926 0.42294900140520963 EVIEIEDASPT(ph)KCPITTK ddPTM_PC-9_Lapatinib_30min_R1 1 EVIEIEDASPTKCPITTK 18 1 P46100-4;P46100;P46100-2;P46100-5;P46100-3 P46100-4 ATRX Transcriptional regulator ATRX 1 EVIEIEDAS(0.318)PT(0.659)KCPIT(0.019)T(0.003)K 56.746 0.02607 7083200.0 29027.0 34508.0 33098.0 30922.0 42248.0 33557.0 28829.0 29737.0 34261.0 26614.0 True False 28613.069657100128 34428.09884616522 30376.810201974717 33196.107032768115 39763.05570276379 32121.84533518765 30321.624558619656 31118.68958025576 30402.165395675715 31214.194439074105 0.9166685276132619 1.1029629136630204 0.9731729665894838 1.0634939529694556 1.2738773630815914 1.0290781457738771 0.9714050003053378 0.9969403388255059 0.9739852634998042 1.0 14.929914613444149 -10.275045636914358 5.334068742172958 0.999999991456318 1.038696591123783 0.008485329140325182 0.0947581509605137 9.981880684258951e-09 2.403518892269525e-09 0.09559681594788151 0.023185628325010036 5.308286602963557e-11 10.275045636914358 0.03869659966746508 EVIGGLCSLANIPLT(ph)PETQR ddPTM_PC-9_AZD4547_30min_R2 2 EVIGGLCSLANIPLTPETQR 20 0 Q01664 Q01664 TFAP4 Transcription factor AP-4 1 EVIGGLCSLANIPLT(0.998)PET(0.002)QR;EVIGGLCS(0.374)LANIPLT(0.623)PET(0.003)QR 128.74 6.9464e-05 14153300.0 32010.0 26125.6 34700.0 38593.0 35098.0 37891.0 37810.0 36372.0 38414.0 43238.0 True False 42188.51415063839 34570.18928604666 34239.85532742278 29695.980105906223 30225.24853557955 35521.669780077886 41175.01675232445 30751.543145411877 40444.48561626472 41724.25078062294 1.0111269432363554 0.8285394857731351 0.820622412310014 0.7117199122889287 0.7244048238157074 0.8513435020521547 0.9868365754202216 0.7370184621671656 0.9693280252990772 1.0 15.348598523690127 -8.412821526679382 6.332347811407897 0.9989377789628268 0.8315486347006846 0.28566557482579025 0.09578003949751053 0.293997743378733 13.590273511229391 0.09533285180050559 0.024700578156605986 3.865257871954869e-09 8.412821526679382 -0.16738914426214213 EVIGGLCSLANIPLT(ph)PETQR ddPTM_PC-9_Lapatinib_30min_R1 1 EVIGGLCSLANIPLTPETQR 20 0 Q01664 Q01664 TFAP4 Transcription factor AP-4 1 EVIGGLCS(0.001)LANIPLT(0.995)PET(0.004)QR 98.882 0.00093635 6047100.0 16681.0 17686.0 22641.0 20424.0 20725.0 18383.0 19113.0 17996.0 21699.0 16700.0 True False 16443.12588107924 17645.049153624608 20779.544376787417 21926.049092466717 19505.99624691773 17596.801942866008 20102.577619372754 18832.159857627943 19255.030119400122 19586.57274864875 0.8395101119573677 0.9008747666097897 1.0609076250065734 1.1194428639374576 0.9958861357336455 0.8984114867201557 1.0263448270070425 0.9614831598819221 0.9830729636316032 1.0 14.25757735698677 -5.065043391061769 4.619549376404394 1.00456614932808 0.8508956635163947 0.5013466673901715 0.05550297615041974 0.1725024090772658 7.166163283945854 0.015710649512234255 0.04880145793111364 8.609077332081182e-06 5.065043391061769 -0.1536704858116853 EVIKS(ph)PTASR ddPTM_PC-9_Lapatinib_30min_R1 1 EVIKSPTASR 10 1 O94885 O94885 SASH1 SAM and SH3 domain-containing protein 1 1 EVIKS(0.859)PT(0.14)AS(0.001)R 64.827 0.023781 15726000.0 70243.0 71485.0 59083.0 69485.0 85324.0 71601.0 74064.0 78792.0 89905.0 57901.0 True False 69241.32193901128 71319.48087452541 54225.423806975385 74595.15869516511 80305.41007343824 68538.79214008314 77898.67152206482 82452.96396433754 79778.95215837906 67909.11070176713 1.0196175627022235 1.050219626461248 0.7984999839729064 1.0984558319834394 1.1825425078250735 1.0092724147291716 1.1471019236898612 1.2141664514860442 1.1747901177610776 1.0 16.05131751929958 -5.973945800917487 24.937179786754932 1.1288709104503447 0.9626821343843165 0.4035084870479301 0.09020457798765051 210.06888032799858 201061.09977733268 0.02535900210978975 0.03761216499316064 1.0618280629483416e-06 5.973945800917487 -0.16618877606602822 EVLAS(ph)PDRLWGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVLASPDRLWGSR 13 1 Q9C0C2;E9PKK0 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 EVLAS(1)PDRLWGSR 75.02 0.008884200000000002 7246400.0 6835.8 10575.0 10367.0 13232.0 12437.0 10808.0 13000.0 13506.0 13943.0 11062.0 True False 7992.965926795769 11624.816112259745 10614.188597066433 12490.653938722813 10000.05912975152 10241.209453603404 11768.545888150487 13151.481810789881 14146.889997435535 13067.45303325619 0.6116697650608701 0.8896007571387488 0.8122614690141768 0.9558598685554527 0.7652645932073936 0.7837188645361801 0.9005998229494278 1.006430386802986 1.0826050004872578 1.0 13.673690353554724 -7.649852807168379 2.5069748160088627 1.0416072610309846 0.8131612161319748 0.5806208988256312 0.08608924305032047 0.21271297898493643 2.682868635459242 0.050547263973991986 0.024581591863741047 2.2394800235309322e-08 7.649852807168379 -0.22844604489900977 EVLAS(ph)PDRLWGSR ddPTM_PC-9_Lapatinib_30min_R1 1 EVLASPDRLWGSR 13 1 Q9C0C2;E9PKK0 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 EVLAS(0.999)PDRLWGS(0.001)R 62.69 0.022855 6730900.0 11005.0 11938.0 12247.0 14399.0 12260.0 11869.0 9586.3 11615.0 13716.0 10952.0 True False 10848.06668193017 11910.358294468533 11240.098934787122 15457.950493655899 11538.890904087391 11361.390537990357 10082.631707873863 12154.675302642174 12171.159644116866 12845.038607377315 0.8445335988090981 0.9272341375157903 0.87505372917537 1.2034179862081462 0.8983150036980222 0.8844964102688759 0.7849436670500224 0.9462544780255745 0.9475378016479126 1.0 13.648923605995893 EVLDEDT(ph)DEEKETLK ddPTM_PC-9_AZD4547_30min_R2 1 EVLDEDTDEEKETLK 15 1 Q9Y3P9 Q9Y3P9 RABGAP1 Rab GTPase-activating protein 1 1 EVLDEDT(1)DEEKETLK 86.803 0.0038653 6647700.0 19105.0 22451.0 16292.0 16668.0 18296.0 20197.0 21076.0 15677.0 19769.0 23057.0 True False 25179.992591313556 29707.846696766155 16075.957434996306 12825.450118032915 15755.916211948355 18934.07839719811 22951.723170377958 13254.47987162162 20813.94898078662 22249.7814480046 1.1316961764391507 1.3351972362600626 0.7225220379159286 0.5764303864289474 0.7081380214348746 0.8509781743899401 1.031548252463231 0.5957128119481059 0.9354675698467704 1.0 14.44150354459799 -5.264374624384208 24.998577437307414 0.7866142566836 1.233446724581641 0.5478683325669604 0.15601906813246474 166.39429529358733 1417142.2626601174 0.0407521595937298 0.09125882358715638 5.440331649118575e-06 5.264374624384208 0.446832467898041 EVLDEDT(ph)DEEKETLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVLDEDTDEEKETLK 15 1 Q9Y3P9 Q9Y3P9 RABGAP1 Rab GTPase-activating protein 1 1 EVLDEDT(0.998)DEEKET(0.002)LK 104.2 0.00084789 8030600.0 24501.0 22789.0 15474.0 20476.0 24710.0 21924.0 22938.0 25573.0 17996.0 17864.0 True False 28648.535383191895 25051.341312745826 15842.958845471792 19328.796104087683 19868.252882219185 20774.266845003785 20765.14658326122 24901.735846833242 18259.157454912853 21102.6017886538 1.3575830918913185 1.1871209798506996 0.7507585559421421 0.9159437446466987 0.9415072644218551 0.9844410207358152 0.9840088341346601 1.1800315475896492 0.8652562199572104 1.0 14.36513326266127 -5.033504194746062 5.906254429022691 0.9593787926765851 1.3215759863747767 0.6204284050013389 0.10378499681140332 0.10434929946609905 11.27136821580713 0.027310320385845445 0.08223202555186156 9.257544434378854e-06 5.033504194746062 0.3621971936981916 EVLDEDT(ph)DEEKETLK ddPTM_PC-9_Lapatinib_30min_R1 1 EVLDEDTDEEKETLK 15 1 Q9Y3P9 Q9Y3P9 RABGAP1 Rab GTPase-activating protein 1 1 EVLDEDT(1)DEEKETLK 74.726 0.011318 6855600.0 13187.0 17860.0 15256.0 16229.0 17236.0 14808.0 14143.0 18551.0 14958.0 10647.0 True False 12998.950961800374 17818.64626731512 14001.710569863015 17422.53479835695 16222.21236727981 14174.696359133972 14875.255337769524 19412.94718375506 13273.272525277063 12487.319763764266 1.0409720586735323 1.4269392154929283 1.1212742874170014 1.395218119497004 1.2990948157148554 1.135127203218271 1.1912288320616706 1.5546128033084885 1.062940068516022 1.0 13.608176234520094 -8.501819397924699 24.68088245867623 0.9999998481043778 1.2712449303899809 0.2970358933486824 0.1487045494903408 624.2850139808868 731642.6178474049 0.13491166500156132 0.03483404211746788 3.149057582631907e-09 8.501819397924699 0.27124508228560307 EVLDQVCYR ddPTM_PC-9_Lapatinib_30min_R1 1 EVLDQVCYR 9 0 Q15459;Q15459-2 Q15459 SF3A1 Splicing factor 3A subunit 1 0 93.111 0.019196 0.0 10566.0 11412.0 12358.0 10599.0 12234.0 10604.0 11270.0 10383.0 9682.1 11594.0 False True 10415.326902432906 11385.57621515119 11341.972943259512 11378.485817227509 11514.420172969425 10150.491639131329 11853.505455466486 10865.432085005055 8591.599940967046 13598.007451966083 0.7659450797643881 0.8372973948844978 0.8340908021505474 0.8367759657009408 0.8467726035335126 0.7464690451882131 0.8717089983468596 0.7990458987014355 0.6318278594357455 1.0 13.731107645012505 -6.662089981747447 17.347785951804386 0.8005848442890424 0.8261489961418612 0.0008293919256133764 0.08977140247969 9.481256371149138 1621.223432228587 0.02837381077173383 0.028373524354049946 2.177258618031875e-07 6.662089981747447 0.025564151852818795 EVLEEER ddPTM_PC-9_AZD4547_30min_R2 1 EVLEEER 7 0 A0A1B0GVM6 A0A1B0GVM6 0 85.265 0.0092201 0.0 9280.8 9816.4 12379.0 13216.0 16871.0 10905.0 9411.6 11816.0 8737.1 11718.0 False True 12231.901347367844 12989.359329835428 12214.846371705084 10169.25538516458 14528.75286465789 10223.108626105124 10249.214167314916 9990.108704668057 9198.925268856834 11307.756386681618 1.081726642234236 1.148712342718527 1.080218387627438 0.899316808517561 1.284848414471503 0.9040793130409139 0.9063879532624648 0.883473994579022 0.8135057879113327 1.0 13.465025086869714 -6.950765611076153 24.996685942386417 0.8931458346710638 1.090082500474243 0.5023568317089262 0.09795873512312803 91.65457226071115 46533.40557815576 0.03341381405905584 0.029468207661330834 1.1200422076500107e-07 6.950765611076153 0.19693666580317915 EVLEEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EVLEEER 7 0 A0A1B0GVM6 A0A1B0GVM6 0 ; 76.774 0.02582 15655000.0 22954.8 20148.8 26431.0 24571.1 25927.6 22982.0 25522.2 23378.0 21354.9 17260.5 False True 26840.594262033905 22149.03970521978 27061.21528012569 23194.460927581014 20847.272902833938 21776.783462501236 23104.55245127341 22764.35227103849 21667.17501299838 20389.692015957182 1.3163805633272039 1.0862861335956284 1.3272007865026751 1.137558179369693 1.0224417753107133 1.0680290533794479 1.1331486730251517 1.1164637628279463 1.0626533738734958 1.0 14.315552363319506 -1.522878745283349 0.2252986608838621 1.0285106034951592 2.3527220919087957 0.4742237553892882 0.07692353488188149 50.07580641356602 0.6484732925908501 0.11871664334553036 24.291340561446503 0.029999999999791978 1.522878745283349 1.3242114884136365 EVLEEER ddPTM_PC-9_Lapatinib_30min_R1 1 EVLEEER 7 0 A0A1B0GVM6 A0A1B0GVM6 0 78.616 0.02356 20833000.0 6666.1 5742.4 5054.9 5624.4 6050.0 5334.1 4147.1 3375.9 5564.6 3470.4 False True 6571.040191586981 5729.103825612002 4639.305634478279 6038.03713844838 5694.150894757649 5105.972977394416 4361.816546083855 3532.756638328862 4937.856150164242 4070.2540159826704 1.614405431647379 1.4075543696082664 1.1398073968506912 1.4834546234065031 1.3989669618648914 1.2544605219587739 1.0716325145694363 0.8679450040358129 1.213156754044037 1.0 11.990903117522905 -7.113523179117674 2.413584318823065 1.021370793349367 1.3973743572245148 0.6244192806772817 0.1353643388846997 0.20661182706131306 2.3566359161054766 0.06036105161802362 0.04439392849017646 7.699753482199689e-08 7.113523179117674 0.3760035638751478 EVLHGNQR ddPTM_PC-9_AZD4547_30min_R2 4 EVLHGNQR 8 0 P62906 P62906 RPL10A 60S ribosomal protein L10a 0 ;;; 122.74 0.0027825 18651300.0 56996.1 39890.200000000004 48268.5 54747.2 46561.4 43158.3 39764.2 39381.3 59793.0 70705.0 False True 75119.67420747259 52783.927054623025 47628.428151922366 42126.07887580828 40097.15331826697 40459.60467840741 43303.13676653742 33295.82497724645 62953.53591017116 68229.63947092692 1.1009830154456781 0.7736216615524487 0.6980606745286576 0.6174161142058865 0.5876793960688099 0.5929916234666242 0.6346675301573176 0.48799649588407995 0.922671384435441 1.0 16.058110972590484 -4.644524151907964 1.7968592864799622 0.6609451982240091 1.3686256456468324 0.38422620924170137 0.15065286462605249 1.1955257928799132 2.972915650679359 0.0383629169612121 1.6171212404526365 2.2671269945736686e-05 4.644524151907964 0.7076804474228233 EVLHGNQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 EVLHGNQR 8 0 P62906 P62906 RPL10A 60S ribosomal protein L10a 0 ;;;; 128.61 0.0029781 17047300.0 60656.200000000004 87162.0 76058.0 69404.1 132021.0 107549.0 63788.5 92168.0 105615.0 95875.0 False True 70924.09664544153 95814.86732640975 77871.5111715713 65515.61328812809 106152.43277067851 101908.94111080597 57745.99149125287 89748.68766006817 107159.41957105044 113256.37855391757 0.6262260682445973 0.8459997445600426 0.6875684369026446 0.578471730463625 0.9372755347297538 0.8998075200002138 0.5098696623410216 0.7924382609262208 0.9461667496284585 1.0 16.789232779003818 -8.248494372510956 3.591126841771696 0.9869249982798738 0.7340145282789452 0.3548576840003551 0.13083380231292005 0.2657827944315892 7.070757113778808 0.11603934212209129 0.03447964539128651 5.642942532942215e-09 8.248494372510956 -0.2529104700009286 EVLHGNQR ddPTM_PC-9_Lapatinib_30min_R1 5 EVLHGNQR 8 0 P62906 P62906 RPL10A 60S ribosomal protein L10a 0 ;;;; 143.89 0.0014177999999999999 23595360.0 59951.9 73044.0 47626.600000000006 44308.5 57383.8 44198.9 67089.6 80101.0 71666.1 53155.8 False True 59096.974912168014 72874.87110581007 43710.92479199254 47567.09489882301 54008.597704891574 42308.61607966822 70563.171216066 83822.78488307697 63594.3091405106 62343.70920434865 0.9479220223882001 1.1689210031912385 0.7011280745057688 0.7629814700775788 0.8663038884623233 0.6786348874589753 1.1318410809465282 1.3445267526243063 1.0200597614758975 1.0 15.927956371720416 -7.362308882562586 7.788137299027997 1.1556224845476566 0.8583880223604434 0.40692728446796866 0.1578481314854643 0.2869329265001009 19.75659995348151 0.06883092196653352 0.046236984364688365 4.342012980385001e-08 7.362308882562586 -0.29723446218721317 EVLT(ph)PTSTSDNETR ddPTM_PC-9_AZD4547_30min_R2 1 EVLTPTSTSDNETR 14 0 H7C183;Q70CQ2-3;Q70CQ2-2;Q70CQ2;H7C150 H7C183 USP34 Ubiquitin carboxyl-terminal hydrolase 34 1 EVLT(0.288)PT(0.174)S(0.107)T(0.107)S(0.107)DNET(0.218)R 79.61399999999999 0.030726999999999997 4826100.0 21629.0 22196.0 24921.0 31882.0 26295.0 20771.0 21678.0 16903.0 15363.0 22170.0 True False 28506.57208885216 29370.422933562924 24590.531256907856 24532.097471989786 22644.39313473886 19472.18608645847 23607.300004149405 14291.029742298924 16175.056815813878 21393.8350480228 1.332466667376998 1.3728451615914143 1.1494213731062908 1.1466900355603622 1.058454133347711 0.9101774433031385 1.1034627476166865 0.6679975661315426 0.7560615840734344 1.0 14.384907502016434 -6.0927715829052485 0.5940965551839839 0.8227547601498663 1.4138507908251272 0.7092344564660147 0.11572102883739949 0.5957672825942862 0.4082950997730861 0.08058324387633664 0.1998936209877829 8.076597070189604e-07 6.0927715829052485 0.591096030675261 EVLTPT(ph)STSDNETR ddPTM_PC-9_Lapatinib_30min_R1 2 EVLTPTSTSDNETR 14 0 H7C183;Q70CQ2-3;Q70CQ2-2;Q70CQ2;H7C150 H7C183 USP34 Ubiquitin carboxyl-terminal hydrolase 34 1 EVLT(0.243)PT(0.451)S(0.243)T(0.054)S(0.009)DNET(0.001)R;EVLT(0.061)PT(0.262)S(0.262)T(0.262)S(0.152)DNETR 105.19 0.0024321 8769800.0 59432.0 61448.0 56214.0 59135.0 65981.0 66782.0 55057.0 54890.0 62228.0 56502.0 True False 58584.488781506036 61305.72093135388 51592.301912315124 63483.9851685771 62100.12730363705 63925.8895364455 57907.58206403 57440.38978579674 55219.2273501097 66268.29541581753 0.8840500334873945 0.9251138956672312 0.7785367284398355 0.9579842784582046 0.9371016247509275 0.964652691537122 0.8738353944472832 0.8667853824422702 0.8332676584424332 1.0 16.016031189762423 -10.635257180947201 4.753550234525955 1.000006446352572 0.8931762664335409 0.26032972499127716 0.054903103948120396 3.8627525601317335e-06 7.213316044471095e-07 0.05474536244860013 0.013276899466173043 2.3160227391018527e-11 10.635257180947201 -0.1068301799190311 EVLTPTST(ph)SDNETR ddPTM_PC-9_AZD4547_30min_R2 1 EVLTPTSTSDNETR 14 0 H7C183;Q70CQ2-3;Q70CQ2-2;Q70CQ2;H7C150 H7C183 USP34 Ubiquitin carboxyl-terminal hydrolase 34 1 EVLTPT(0.071)S(0.071)T(0.429)S(0.429)DNETR 185.2 1.4687999999999999e-05 3762900.0 16703.0 20041.0 26127.0 29297.0 30016.0 20458.0 24083.0 33474.0 22935.0 24608.0 True False 22014.206556017278 26518.861326884777 25780.53890892148 22543.029284137905 25848.79651387417 19178.758025938456 26226.340345047087 28301.362455996823 24147.297277269496 23746.481410092263 0.9270513039738693 1.1167490824815103 1.0856572164819644 0.9493208233602605 1.0885316467511865 0.807646307456206 1.1044305845623463 1.1918128823905985 1.0168789582024933 1.0 14.535426140223592 EVLTPTST(ph)SDNETR ddPTM_PC-9_Lapatinib_30min_R1 1 EVLTPTSTSDNETR 14 0 H7C183;Q70CQ2-3;Q70CQ2-2;Q70CQ2;H7C150 H7C183 USP34 Ubiquitin carboxyl-terminal hydrolase 34 1 EVLTPT(0.059)S(0.059)T(0.551)S(0.331)DNETR 168.0 0.00090643 4025300.0 22631.0 24852.0 28112.0 21836.0 25258.0 26622.0 22760.0 24058.0 27852.0 24752.0 True False 22308.277789982876 24794.45672090233 25800.739875458126 23441.892282760626 23772.374099138608 25483.43911891307 23938.401434464693 25175.822508046964 24715.014465437664 29030.350220033153 0.7684467331912677 0.8540874131030037 0.8887505551914993 0.807496020719169 0.8188800313794995 0.8778205886516504 0.8245991265356961 0.8672242090511787 0.8513508889183989 1.0 14.825274356187029 -14.52287874528033 0.24291122489009698 1.924768893533789 0.8263913559549294 0.6929368904399538 0.03269755557035641 100.05090693308232 0.994510968234796 45.72976289883995 0.050028274371711846 3.0000000000000503e-15 14.52287874528033 -1.0983775375788596 EVLTPTSTS(ph)DNETR ddPTM_PC-9_AZD4547_30min_R2 1 EVLTPTSTSDNETR 14 0 H7C183;Q70CQ2-3;Q70CQ2-2;Q70CQ2;H7C150 H7C183 USP34 Ubiquitin carboxyl-terminal hydrolase 34 1 EVLT(0.001)PT(0.085)S(0.085)T(0.19)S(0.638)DNETR 133.04 1.1385e-05 3351300.0 17716.0 16267.0 27715.0 32968.0 25159.0 23218.0 18971.0 30023.0 24665.0 28947.0 True False 23349.31948430834 21524.9896314772 27347.480991340693 25367.736950522536 21666.10712595151 21766.174789629436 20659.382248303278 25383.63520990597 25968.741545404515 27933.574340781062 0.8358872802833531 0.770577705841684 0.9790183188771258 0.9081450386922886 0.7756296011971697 0.779211944883557 0.7395896420653202 0.9087141838789904 0.9296605306787384 1.0 14.769712570202193 -8.207383079119335 2.3360850993740576 0.9821851912739068 0.8304590743480726 0.38530720864961143 0.07010791448503297 0.3483058687538081 3.410587197503206 0.06921307757761636 0.020511112687126732 6.2032162433494146e-09 8.207383079119335 -0.15172611692583415 EVLYDS(ph)EGLSGEER ddPTM_PC-9_Lapatinib_30min_R1 3 EVLYDSEGLSGEER 14 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 EVLYDS(1)EGLSGEER;EVLYDS(1)EGLSGEER;EVLYDS(0.5)EGLS(0.5)GEER 159.41 1.1581e-12 0.0 22072.2 21780.2 27496.5 18699.2 26878.5 23995.1 24797.5 22559.999999999996 25791.6 19323.6 True False 21757.446380454254 21729.7692850715 25235.843909559415 20074.40154670258 25297.559475164184 22968.88550831008 26081.393214900643 23608.219959329093 22886.678410411543 22663.658512921495 0.9600147464298153 0.9587935360340192 1.1134938295673407 0.8857529129843413 1.116216936499506 1.0134676841876418 1.1508024267145818 1.0416773596314586 1.009840419072803 1.0 14.468093148581316 -6.287247794528177 24.99847260157477 1.0600980908102 0.9876037055842736 0.2187945531328045 0.06916720963880989 1202.1887308723938 1164456.9953860196 0.020724154340096872 0.02350742464910748 5.161218026670818e-07 6.287247794528177 -0.07249438522592644 EVLYDSEGLS(ph)GEER ddPTM_PC-9_AZD4547_30min_R2 1 EVLYDSEGLSGEER 14 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 EVLYDS(0.02)EGLS(0.98)GEER 132.65 0.00023076 0.0 16514.0 18409.0 22707.0 25879.0 23195.0 22314.0 17894.0 23058.0 19782.0 23642.0 True False 21765.108487461486 24359.349242384204 22405.890343509753 19912.996376564322 19974.7746248438 20918.702052536446 19486.531334728745 19494.9159201283 20827.636134246586 22814.300776064738 0.9540116395018341 1.0677228060366606 0.9820984900407966 0.8728295717682362 0.8755374456095547 0.9169118202598158 0.8541366893511253 0.8545042038097912 0.9129202046857193 1.0 14.477650817581873 -5.653272504528469 4.620880381829985 0.8902257484851481 1.013747274352492 0.49160260475689 0.04799115992512852 0.1454482935543036 5.218831390533435 0.012417038136224875 0.02204249006541035 2.2219152793914934e-06 5.653272504528469 0.12352152586734388 EVLYDSEGLS(ph)GEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EVLYDSEGLSGEER 14 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 EVLYDS(0.008)EGLS(0.992)GEER;EVLYDS(0.195)EGLS(0.805)GEER 133.48 1.0008e-05 4464800.0 26132.1 21694.8 30816.5 36836.3 33217.4 31403.0 30733.8 26221.1 30051.4 19712.7 True False 30555.7483974984 23848.516368061704 31551.28223222707 34772.481535895924 26708.688923101094 29756.171398177983 27822.471970556886 25532.82390855195 30490.844873336748 23286.45646435266 1.3121682315329386 1.0241367725729098 1.3549198556906397 1.493249159189432 1.1469623540184077 1.2778316633846494 1.1947920033753543 1.0964666928881202 1.309381052459085 1.0 14.507203498692274 -10.106177956482895 0.34642412899935615 0.9166020727677523 1.2684707027363529 0.25085238866347703 0.12857754273771027 14.082736468329506 1.6474501913456572 1.4737564508924907 0.11462926701888554 7.831086904402972e-11 10.106177956482895 0.3518686299686006 EVMDTT(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVMDTTK 7 0 A0A087WV20;A0A087WTU9;Q8TCU4-3;Q8TCU4-2;Q8TCU4;A0A494C003;A0A494C0F1;A0A494C1N9 A0A087WV20 ALMS1 Alstrom syndrome protein 1 1 EVMDT(0.003)T(0.997)K 99.919 0.028575 11188000.0 25686.0 32096.0 36094.0 25332.0 24478.0 17094.0 22783.0 22802.0 16001.0 22493.0 True False 30034.132478375017 35282.278764925664 36954.61784725725 23912.7301674521 19681.71161679326 16197.560547732835 20624.829305364026 22203.471660716034 16234.984354082044 26570.802845509967 1.1303434319618346 1.3278589649724413 1.3907979394571428 0.8999626509777428 0.7407270202269839 0.6095999673743377 0.7762215325326267 0.8356342030691805 0.611008423361415 1.0 14.697554199539594 -5.899761094450626 4.2088425122401105 0.7518708534237483 1.2855073500593248 0.7832527310653449 0.12223141144275222 0.09111338843589889 2.931748457298339 0.03452626132654286 0.052820048533224286 1.259618137629052e-06 5.899761094450626 0.5336364966355766 EVMDTT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 EVMDTTK 7 0 A0A087WV20;A0A087WTU9;Q8TCU4-3;Q8TCU4-2;Q8TCU4;A0A494C003;A0A494C0F1;A0A494C1N9 A0A087WV20 ALMS1 Alstrom syndrome protein 1 1 EVMDT(0.005)T(0.995)K 105.1 0.025067 18699000.0 42754.0 54304.0 65220.0 66267.0 60005.0 68123.0 58936.0 63498.0 61660.0 63136.0 True False 42144.32011987662 54178.26242442779 59857.863356480506 71140.49624023176 56475.62387436901 65209.53809246921 61987.41770393729 66448.34889084578 54715.20149141488 74048.97347656818 0.5691411796979553 0.7316544697486156 0.8083550729494142 0.9607222477262731 0.7626793623579398 0.8806271718689511 0.8371138017673181 0.8973567866119371 0.7389056042583599 1.0 16.176192115461554 -4.873119473859609 1.6853251328203387 0.8592509633747711 0.5012840971214173 0.5953409922241526 0.07603525657691178 0.5213478262682988 1.705419935742953 0.019875840971193024 0.2890153893269024 1.3393081947613626e-05 4.873119473859609 -0.35796686625335383 EVMES(ph)AVGNSSGSGQNEESPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVMESAVGNSSGSGQNEESPR 21 0 Q9NVF7 Q9NVF7 FBXO28 F-box only protein 28 1 EVMES(0.614)AVGNS(0.152)S(0.053)GS(0.089)GQNEES(0.091)PR 94.54700000000001 0.00033019 7874400.0 26854.0 27052.0 33690.0 30030.0 40999.0 30626.0 34337.0 31037.0 29717.0 24846.0 True False 31399.85180932349 29737.543779560343 34493.29737003648 28347.516458573606 32965.54026378409 29019.918646008304 31084.35078164792 30222.311636419796 30151.554905959405 29350.383119172235 1.0698276639807303 1.013190991709243 1.1752247740679336 0.965831224194701 1.1231724005077932 0.988740710067663 1.059078195178414 1.029707568507956 1.0272968084789267 1.0 14.841091714929833 -7.6997997775789715 0.3955638926280246 1.0002233806671275 1.0715759630870179 0.11168975532186387 0.057253007116222505 2.5863080974369157 1.0998816091831698 0.06467056741329108 0.05867887427044854 1.9961824011587927e-08 7.6997997775789715 0.0713525824198904 EVMESAVGNSS(ph)GSGQNEESPRK ddPTM_PC-9_AZD4547_30min_R2 1 EVMESAVGNSSGSGQNEESPRK 22 1 Q9NVF7 Q9NVF7 FBXO28 F-box only protein 28 1 EVMES(0.042)AVGNS(0.259)S(0.661)GS(0.014)GQNEES(0.025)PRK 53.262 0.0073783 7550600.0 12508.0 10034.0 12382.0 18392.0 15374.0 12418.0 10277.0 14496.0 11853.0 12308.0 True False 16485.283817437845 13277.2942744355 12217.80658974492 14152.008553567404 13239.585474556963 11641.50049692558 11191.633090812966 12255.976284941444 12479.5253816209 11877.100666263636 1.387988893978439 1.1178901861250576 1.0286859506418973 1.1915373079025542 1.1147152698775555 0.9801634947822522 0.9422866240918788 1.0318996722621023 1.0507215297979604 1.0 13.53589508059531 -1.5228787452803376 0.7762700603460438 1.029064409514226 73.09768750134245 0.7107939401179804 0.06605366085982695 266.5799929734826 1.0290521298117867 0.026669438000356788 33701.58039060968 0.029999999999999995 1.5228787452803376 72.06862309182823 EVMESAVGNSSGS(ph)GQNEESPRKR ddPTM_PC-9_AZD4547_30min_R2 1 EVMESAVGNSSGSGQNEESPRKR 23 2 Q9NVF7 Q9NVF7 FBXO28 F-box only protein 28 1 EVMESAVGNS(0.026)S(0.356)GS(0.599)GQNEES(0.019)PRKR 59.792 0.014788999999999998 11721000.0 32228.0 19463.0 45776.0 92271.0 79315.0 38359.0 29865.0 40153.0 31754.0 47042.0 True False 42475.8336159567 25754.034130290842 45168.98033049291 70999.34652273917 68303.481326557 35960.40566609506 32522.92714382889 33948.276474148326 33432.45161292415 45395.073898470444 0.9356925756075901 0.567331032170841 0.995019425048559 1.5640319626207602 1.504645228231657 0.7921653734174606 0.7164417711174764 0.7478405377216973 0.736477523700003 1.0 15.47024812975642 -6.9488871862959805 24.998967093004058 0.7756209742724087 1.106168184009336 0.24472014298044364 0.27501577016966594 169.09393761700204 82702.11472935112 0.11095000503814559 0.09784869027577311 1.1248971428467363e-07 6.9488871862959805 0.3305472097369273 EVMESAVGNSSGSGQNEES(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 EVMESAVGNSSGSGQNEESPR 21 0 Q9NVF7 Q9NVF7 FBXO28 F-box only protein 28 1 EVMESAVGNS(0.001)SGS(0.001)GQNEES(0.998)PR;EVMES(0.45)AVGNS(0.008)S(0.008)GS(0.009)GQNEES(0.526)PR 133.21 3.0587e-05 26836000.0 37457.0 34566.0 49562.0 50779.0 54125.0 49678.0 44942.0 55316.0 46489.0 45029.0 True False 49367.54684600009 45738.78352502866 48904.7754967645 39072.68607772943 46610.67801550639 46571.626806753855 48941.75093580974 46768.18323522496 48946.31363082547 43452.54841576091 1.1361254666502765 1.0526145230284927 1.1254754273290444 0.8992035565756866 1.0726799627383874 1.0717812534525963 1.1263263656604732 1.076304726428 1.1264313697438257 1.0 15.407153170604444 -6.752946797629069 3.7804567513244054 1.0887324626112131 1.0512697369271573 0.021601929507110595 0.06868222413854523 0.7393619469160804 22.942005324950035 0.02438816507138319 0.022904013931189907 1.766254178844961e-07 6.752946797629069 -0.03746272568405584 EVMESAVGNSSGSGQNEES(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EVMESAVGNSSGSGQNEESPR 21 0 Q9NVF7 Q9NVF7 FBXO28 F-box only protein 28 1 EVMESAVGNSSGS(0.001)GQNEES(0.999)PR;EVMESAVGNS(0.007)S(0.007)GS(0.026)GQNEES(0.959)PR;EVMESAVGNS(0.003)S(0.003)GS(0.042)GQNEES(0.952)PR 122.35 1.2569e-06 19126300.0 51527.8 61144.0 63875.0 59285.0 67762.0 63103.0 70146.0 53742.0 54655.2 46770.0 True False 60250.438819559786 67213.97223338154 65398.02224728647 55963.4536545633 54484.52253358713 59793.76759351731 63501.263066938795 52331.32944435584 55454.42890252021 55249.030768883706 1.090524810681256 1.2165638256089826 1.1836953759579558 1.0129309578057242 0.9861625041261873 1.0822591231264314 1.1493642907977084 0.9471899998258229 1.0037176784964015 1.0 15.7536615351451 -5.760979884366185 24.999950181600568 1.029577056593856 1.1688916109093919 0.522156870265792 0.06020846354052847 10.006877028305068 544376.1512863259 0.017485338179012044 0.02806936164592647 1.733884305875696e-06 5.760979884366185 0.13931455431553585 EVMESAVGNSSGSGQNEES(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 EVMESAVGNSSGSGQNEESPR 21 0 Q9NVF7 Q9NVF7 FBXO28 F-box only protein 28 1 EVMESAVGNS(0.066)S(0.066)GS(0.019)GQNEES(0.849)PR;EVMESAVGNS(0.001)S(0.001)GS(0.036)GQNEES(0.962)PR;EVMESAVGNSSGSGQNEES(1)PR;EVMESAVGNSSGSGQNEES(1)PR 250.84 7.918699999999999e-62 43033700.0 99831.0 105474.0 118833.0 104253.0 108857.0 98866.0 91926.0 99949.0 114866.0 85360.0 True False 98407.39163323665 105229.78143330349 109063.00944864543 111920.11339781288 102454.24528109636 94637.73164790249 96685.47848262762 104592.99542176351 101928.58148739631 100114.36226494948 0.9829497926861345 1.0510957574180637 1.0893842499841695 1.117922652312561 1.0233721012970591 0.9452962542721567 0.9657503308741314 1.0447351714128834 1.0181214681031034 1.0 16.61128943044978 -6.517435629427151 24.9713023417657 0.9944924149099048 1.0628645105031198 0.3643280117582258 0.04076632320944314 275.51032673934463 1263963.673264708 0.01433392485849758 0.014747297087066822 3.0378363227947575e-07 6.517435629427151 0.068372095593215 EVMS(ph)PLQAMSSYTVAGR ddPTM_PC-9_AZD4547_30min_R2 1 EVMSPLQAMSSYTVAGR 17 0 Q9BYT8 Q9BYT8 NLN Neurolysin, mitochondrial 1 EVMS(0.997)PLQAMS(0.002)S(0.001)Y(0.001)TVAGR 84.046 0.0020751 3211100.0 8207.1 10930.0 10044.0 18287.0 14787.0 12165.0 11363.0 15525.0 8589.4 11315.0 True False 10816.787081715223 14462.908752200525 9910.80999736698 14071.214681333575 12734.08029219942 11404.320626920575 12374.2849869522 13125.9679790091 9043.41814839236 10918.865294017955 0.9906512069199483 1.324579831580505 0.9076776506068582 1.2887066835637835 1.1662457544169864 1.0444602364651008 1.1332940423517832 1.2021366346739653 0.8282379079579741 1.0 13.41453531641602 -8.258540774972685 24.99903178389146 0.9141189474695514 1.134607345857662 0.3215363993519236 0.12668747187241244 263.06050597867426 2268817.062912645 0.08726743572020514 0.029695469911303528 5.513904310925068e-09 8.258540774972685 0.22048839838811063 EVMS(ph)PLQAMSSYTVAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EVMSPLQAMSSYTVAGR 17 0 Q9BYT8 Q9BYT8 NLN Neurolysin, mitochondrial 1 EVMS(0.957)PLQAMS(0.032)S(0.01)YT(0.001)VAGR;EVMS(0.976)PLQAMS(0.01)S(0.01)Y(0.002)T(0.001)VAGR 75.445 0.005358399999999999 7378200.0 19330.4 20301.0 22519.0 29287.0 25781.0 26731.0 23127.0 22776.0 20642.0 19132.5 True False 22602.654927196956 22316.349115365017 23055.93836378308 27646.14433973511 20729.398120457023 25329.17930276391 20936.243135019715 22178.154133166776 20943.85019917267 22601.07079721333 1.0000700909261264 0.9874022923779603 1.020125929901774 1.2232227662037953 0.9171865486573724 1.1207070465832507 0.9263385493045362 0.9812877598658423 0.9266751291162278 1.0 14.464103506049788 -7.2824707567396825 24.973196676279354 0.9570160033029246 1.0433673503513399 0.21749668103814523 0.0800601782120293 1307.5549531743889 1552617.6654276955 0.032834680945335044 0.022167134117393204 5.2183024054500164e-08 7.2824707567396825 0.0863513470484153 EVNS(ph)QEEEEEELLRK ddPTM_PC-9_AZD4547_30min_R2 1 EVNSQEEEEEELLRK 15 1 Q96RL1-2;Q96RL1-3;Q96RL1;D6RC40;D6RCQ3;Q96RL1-5 Q96RL1-2 UIMC1 BRCA1-A complex subunit RAP80 1 EVNS(1)QEEEEEELLRK 95.666 0.001281 4840400.0 12415.0 9939.6 13773.0 18326.0 12310.0 14895.0 12132.0 15922.0 13008.0 10439.0 True False 16362.711751958013 13152.381320528113 13590.361020881672 14101.22383387757 10600.968986067135 13963.613295354056 13211.724497201807 13461.620751161541 13695.576323641662 10073.53378738431 1.6243268844196481 1.3056372865895014 1.349115544527353 1.3998289112344446 1.0523585079292994 1.3861683089643801 1.3115282855106558 1.3363354941063816 1.3595602707754308 1.0 13.298282247920172 -14.440886979527804 0.1349970916985119 1.5527308503419135e-29 1.4571632939787176 0.41312071810040585 0.12814187169153907 154.38652650864933 1.318472178295565 42.858243165522985 0.8884735832892696 3.623372805319697e-15 14.440886979527804 1.4571632939787176 EVNS(ph)QEEEEEELLRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVNSQEEEEEELLRK 15 1 Q96RL1-2;Q96RL1-3;Q96RL1;D6RC40;D6RCQ3;Q96RL1-5 Q96RL1-2 UIMC1 BRCA1-A complex subunit RAP80 1 EVNS(1)QEEEEEELLRK 58.073 0.027567 4901700.0 4484.6 3505.2 6507.6 4637.9 4386.1 5271.1 5400.4 5544.4 4922.5 3177.3 True False 5243.7542051125365 3853.17309094022 6662.765864210433 4378.053499274674 3526.675190882301 4994.674236758778 4888.835016489836 5398.865374777386 4994.48225004493 3753.3193385070404 1.3970978038863986 1.026604118495523 1.7751662630605487 1.1664484432108393 0.9396150108253535 1.330735220293169 1.3025363886128778 1.4384242021156919 1.3306840691129649 1.0 11.873951326946933 EVNS(ph)QEEEEEELLRK ddPTM_PC-9_Lapatinib_30min_R1 2 EVNSQEEEEEELLRK 15 1 Q96RL1-2;Q96RL1-3;Q96RL1;D6RC40;D6RCQ3;Q96RL1-5 Q96RL1-2 UIMC1 BRCA1-A complex subunit RAP80 1 EVNS(1)QEEEEEELLRK;EVNS(1)QEEEEEELLRK 95.954 0.0012554 9818300.0 10804.2 10042.7 11384.6 8958.9 11677.3 10942.2 8845.4 7261.299999999999 11626.099999999999 8053.299999999999 True False 10650.130126752383 10019.446745171655 10448.602133826853 9617.767392014302 10990.464172455111 10474.22761351403 9303.371531125404 7598.686506678919 10316.646189739511 9445.30217465227 1.1275584337929845 1.0607862575387137 1.1062221134509675 1.0182593647268232 1.1635905309572296 1.108935153141317 0.9849734142007911 0.8044937436804308 1.092251576389542 1.0 13.205381236797049 -7.345588521473885 4.831837086041186 0.9504032275101714 1.0955614179264979 0.3979853167286066 0.07576606025491132 0.20500287509090487 8.371859988246833 0.031139753079700294 0.02068562367560087 4.512440396944548e-08 7.345588521473885 0.1451581904163265 EVPAHSTEVGR ddPTM_PC-9_AZD4547_30min_R2 1 EVPAHSTEVGR 11 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 0 102.05 0.0033962 0.0 9093.9 7826.8 19790.0 30511.0 17449.0 16774.0 11912.0 21671.0 14296.0 17000.0 False True 11985.571035129355 10356.660038583994 19527.571669443714 23477.160340250924 15026.507541664143 15725.119128316135 12972.144923398282 18322.244900039044 15051.657374137558 16404.83517439728 0.7306120974525249 0.6313175309891219 1.1903546400709974 1.4311122355493877 0.9159804034554234 0.9585661154863679 0.7907513111526817 1.1168807674845906 0.9175134778329499 1.0 14.001833478174191 -5.251537362030148 24.598841329145188 1.0420274181423523 0.6809647581178435 0.4181518088645162 0.16946506463330252 567.4890662603221 1409761.5591159002 0.04673981976292428 0.12045037102565001 5.603542084361867e-06 5.251537362030148 -0.3610626600245088 EVPAHSTEVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVPAHSTEVGR 11 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 0 86.463 0.012032 0.0 8634.1 7024.1 16986.0 18135.0 20057.0 18396.0 16916.0 15429.0 13780.0 12801.0 False True 10095.68259875176 7721.4062273403 17391.010659763728 17118.95474446327 16126.974830379213 17431.281375692826 15313.59401876566 15024.005098376805 13981.506430801239 15121.719967339752 0.6676279299283847 0.5106169300858087 1.1500682923189454 1.1320772227919307 1.0664775478722417 1.1527313965171502 1.0126886393770234 0.9935381114599402 0.9245976291717363 1.0 13.884334622761065 -5.260515793707209 24.9999897989899 1.0590731997128757 0.5891223973862356 0.8462683902627663 0.0792353121936702 28.29852871767723 765967.4363602387 0.021537715477569025 0.05070086439549928 5.488885941667328e-06 5.260515793707209 -0.4699508023266401 EVPAHSTEVGR ddPTM_PC-9_Lapatinib_30min_R1 1 EVPAHSTEVGR 11 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 0 73.95100000000001 0.019688999999999998 3523900.0 13134.0 9242.4 14711.0 9629.9 13842.0 10362.0 11004.0 9487.5 16870.0 8717.6 False True 12946.706751519383 9220.999790651362 13501.518366102184 10338.114970404675 13027.840774419064 9918.841415001774 11573.733277014479 9928.323885821586 14969.922951024471 10224.425544528167 1.2662527293230774 0.9018599382912216 1.3205160825223894 1.0111193949607615 1.2741880429058636 0.970112342429846 1.1319690506434783 0.9710397755436689 1.4641334015128082 1.0 13.319732167719712 -8.225819357822328 24.998839857368004 1.2320678531368483 1.1050312551044819 0.07929677878279473 0.17196818769698166 1261.730007359081 885509.9897289466 0.1047836202057551 0.03960194707093786 5.9453940228075635e-09 8.225819357822328 -0.12703659803236644 EVPSKEEPS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 2 EVPSKEEPSPVK 12 1 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 EVPS(0.001)KEEPS(0.999)PVK;EVPS(0.005)KEEPS(0.995)PVK 63.211999999999996 0.022866 129105000.0 478320.0 613800.0 429580.0 370990.0 403060.0 565120.0 583180.0 574580.0 531200.0 487040.0 True False 630415.8103259393 812198.8464867957 423883.4885174138 285463.9872383627 347102.07632203295 529782.957064148 635081.8902306409 485791.86353488255 559278.1475337071 469988.87784343946 1.34134197647107 1.7281235466966767 0.9019011055376844 0.6073845588606783 0.7385325327584837 1.1272244558106903 1.3512700409948775 1.0336241694994053 1.189981665310836 1.0 18.842267090652676 -5.268322192788827 24.787996190331707 0.989563963691701 1.5347327721269006 0.49189654425961915 0.2199004102055092 389.633568844153 1403244.3539602575 0.06434843003506217 0.13886485136856663 5.3911052079522e-06 5.268322192788827 0.5451688084351997 EVPSKEEPS(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 EVPSKEEPSPVK 12 1 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 EVPS(0.017)KEEPS(0.983)PVK;EVPSKEEPS(1)PVK;EVPS(0.013)KEEPS(0.987)PVK;EVPS(0.067)KEEPS(0.933)PVK;EVPSKEEPS(1)PVK;EVPSKEEPS(1)PVK 93.823 0.0035805 123219600.0 623619.0 976522.0 584817.0 580479.0 623829.0 411749.0 644097.0 435804.0 417180.0 482469.0 True False 729185.3796633099 1073464.65055093 598761.2552108227 547956.6435683095 501594.1856439468 390156.15759731154 583083.4693015433 424364.6067725064 423280.4682729797 569936.8104774969 1.2794144302635821 1.8834801171231141 1.0505748079496329 0.9614340282903077 0.8800873648145446 0.6845603765625106 1.0230668708922872 0.7445818535864894 0.7426796453423538 1.0 19.12044244939095 -5.442983039617703 4.503970707295435 0.8597249419211708 1.577309948870482 0.7260621642515138 0.17376856777678365 0.10090543455645357 3.684575707236327 0.044262730504764626 0.09480420486274073 3.6059272487463553e-06 5.442983039617703 0.7175850069493113 EVPSKEEPS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 3 EVPSKEEPSPVK 12 1 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 EVPS(0.003)KEEPS(0.997)PVK;EVPSKEEPS(1)PVK;EVPS(0.005)KEEPS(0.995)PVK 68.132 0.016627 116041000.0 563632.0 692862.0 514416.0 581940.0 685095.0 570614.0 649741.0 652495.0 571666.0 615061.0 True False 555594.50432255 691257.7206083144 472122.7021831852 624737.8088949303 644799.0590485932 546210.1693862019 683381.4097728712 682812.2997501079 507278.9551701451 721373.4743327341 0.770189817190702 0.958252202505399 0.6544774918704845 0.8660393417886745 0.8938491391647415 0.7571808346452479 0.9473337100521954 0.9465447844221122 0.7032126536665004 1.0 19.460386849111785 -7.2670901907038425 24.911997681661894 0.8948181806636912 0.8214811212386126 0.12434663505637478 0.1066742009473606 1132.1274973294965 4991041.036710417 0.04237775534419698 0.029453539735883164 5.4064203519799564e-08 7.2670901907038425 -0.07333705942507862 EVPSKEEPS(ph)PVKAEVAEK ddPTM_PC-9_AZD4547_30min_R2 2 EVPSKEEPSPVKAEVAEK 18 2 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 EVPS(0.002)KEEPS(0.998)PVKAEVAEK;EVPS(0.018)KEEPS(0.982)PVKAEVAEK 90.884 0.0036385 131070000.0 113099.0 88885.0 92024.0 108219.0 105433.0 98994.0 97942.0 96218.0 91380.0 106024.0 True False 149062.12939465963 117615.33800908922 90803.70163258654 83270.781516883 90795.4478560532 92803.88953073394 106658.64826120513 81349.71896968097 96210.16024403265 102312.1320311942 1.4569350323890398 1.149573717936297 0.8875164638823202 0.8138896127342392 0.8874357913719397 0.9070663242794973 1.0424829015261428 0.7951131244618972 0.9403592548994962 1.0 16.64261770244741 -4.9132157164912105 2.2880655054756636 0.9021891640368811 1.515614322607662 0.848825709091428 0.07228842014163274 0.1562695743638144 1.223812403981513 0.019383660288519296 0.17512676951474418 1.2211929361537967e-05 4.9132157164912105 0.6134251585707808 EVPSKEEPS(ph)PVKAEVAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 EVPSKEEPSPVKAEVAEK 18 2 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 EVPS(0.001)KEEPS(0.999)PVKAEVAEK;EVPS(0.033)KEEPS(0.967)PVKAEVAEK;EVPSKEEPS(1)PVKAEVAEK;EVPS(0.034)KEEPS(0.966)PVKAEVAEK;EVPS(0.001)KEEPS(0.999)PVKAEVAEK;EVPSKEEPS(1)PVKAEVAEK 107.47 0.00082919 566793100.0 460528.0 418955.0 343916.0 531627.0 494587.0 490621.0 554780.0 535471.0 414552.0 390582.9 True False 538486.2945573879 460546.0836228641 352116.26174869254 501841.6627479898 397676.2277724864 464891.97107109067 502227.22214062605 521415.4536284228 420614.0387446673 461392.4879174639 1.1670894274588082 0.9981655438335806 0.7631599364306964 1.0876676059748975 0.8619044266789724 1.007584612331731 1.0885032489529107 1.1300909036943318 0.9116187405719288 1.0 18.815634989657433 -6.998413068024185 24.996245431093804 1.044058397734596 0.9676221500969062 0.0446489532082327 0.11703434583912704 141.11100498166408 2222635.589590015 0.041282117329354426 0.03613957491888664 1.0036607300758032e-07 6.998413068024185 -0.07643624763768986 EVPSKEEPS(ph)PVKAEVAEK ddPTM_PC-9_Lapatinib_30min_R1 5 EVPSKEEPSPVKAEVAEK 18 2 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 EVPSKEEPS(1)PVKAEVAEK;EVPSKEEPS(1)PVKAEVAEK;EVPSKEEPS(1)PVKAEVAEK;EVPSKEEPS(1)PVKAEVAEK;EVPSKEEPS(1)PVKAEVAEK 106.28 0.00090771 582923000.0 395321.0 310457.0 304405.0 339109.0 334701.0 304221.0 297149.0 280936.0 288374.0 279737.0 True False 389683.65004700737 309738.15589092125 279377.9959372802 364048.2070944619 315014.5452274842 291210.17700378824 312533.9212587768 293989.31216729066 255894.28340715665 328089.1677238768 1.1877370190257825 0.9440669987361486 0.8515306917185622 1.1096014221379251 0.9601491796053556 0.8875946104044304 0.9525883570828787 0.896065280688313 0.779953465646022 1.0 18.323728436689898 -6.5600818427114795 5.431931873577375 0.9012196452043831 1.008821005631088 0.23981932474150602 0.09924613089526513 0.3088697456453436 23.1749619455126 0.0331444182438084 0.03365285234982185 2.753709718372268e-07 6.5600818427114795 0.10760136042670487 EVPWS(ph)PSAEK ddPTM_PC-9_AZD4547_30min_R2 4 EVPWSPSAEK 10 0 Q5JSZ5;Q5JSZ5-5;Q5JT00 Q5JSZ5 PRRC2B Protein PRRC2B 1 EVPWS(0.984)PS(0.016)AEK;EVPWS(0.995)PS(0.005)AEK;EVPWS(0.961)PS(0.039)AEK;EVPWS(0.816)PS(0.184)AEK 134.99 0.00011256 126464000.0 346304.0 291146.0 414000.0 493007.0 449439.0 432088.0 342020.0 432357.0 371458.0 406000.0 True False 456421.4684293242 385253.250829659 408510.0894972057 379351.8530322213 387042.15273184696 405069.46905424236 372459.1174194663 365546.1602254709 391092.5115334626 391786.06357678276 1.1649762736899245 0.9833255611813169 1.042686627920713 0.9682627543434185 0.987891578374109 1.033904742185543 0.9506696435782517 0.9330249189780858 0.9982297684685657 1.0 18.57970655410903 EVPWS(ph)PSAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 EVPWSPSAEK 10 0 Q5JSZ5;Q5JSZ5-5;Q5JT00 Q5JSZ5 PRRC2B Protein PRRC2B 1 EVPWS(0.937)PS(0.063)AEK;EVPWS(0.993)PS(0.007)AEK;EVPWS(1)PSAEK;EVPWS(0.999)PS(0.001)AEK;EVPWS(0.953)PS(0.047)AEK 199.12 0.00012306 104591300.0 472791.0 426813.0 472271.0 572662.0 578653.0 536271.0 622855.0 553997.0 504124.0 440606.0 True False 552825.1782520976 469184.1739311499 483531.73173774144 540577.6047352538 465270.09854531765 508148.0047088589 563853.6653203052 539455.1657583428 511495.85979109065 520484.3799648236 1.0621359632146112 0.9014375685258013 0.9290033483241523 1.038604856445045 0.8939175054144035 0.9762982795818034 1.08332485474091 1.0364483287563815 0.982730470846521 1.0 18.98949534250439 -7.021546662585116 24.50976067332561 1.02882732902551 0.9607279668126826 0.20850233869676282 0.05596233318161744 853.740684946014 971144.2746719337 0.020689937532281558 0.016195553101841505 9.515975986224189e-08 7.021546662585116 -0.06809936221282753 EVPWS(ph)PSAEK ddPTM_PC-9_Lapatinib_30min_R1 4 EVPWSPSAEK 10 0 Q5JSZ5;Q5JSZ5-5;Q5JT00 Q5JSZ5 PRRC2B Protein PRRC2B 1 EVPWS(0.998)PS(0.002)AEK;EVPWS(1)PSAEK;EVPWS(0.991)PS(0.009)AEK;EVPWS(0.978)PS(0.022)AEK 154.67 0.00020482 108854000.0 383884.0 368766.0 430133.0 367606.0 422191.0 422972.0 411535.0 396892.0 467840.0 369927.0 True False 378409.743764296 367912.1449839151 394769.1251013951 394640.9715376676 397358.5554394427 404882.47355589026 432842.26864377974 415333.05124547996 415146.9326263955 433868.3890532575 0.872176340364465 0.8479809874757982 0.9098822017497502 0.9095868274681457 0.9158504409747786 0.9331919166533029 0.9976349500554377 0.9572788931495484 0.9568499183180549 1.0 18.726897952000975 -5.921660834958135 0.384117041867773 0.9922583815743553 0.8192847305910343 0.8385737873870351 0.01886309333539847 0.9882521883620259 0.21601229141792921 0.019055183835819927 0.07309432634918289 1.1976754984845302e-06 5.921660834958135 -0.17297365098332096 EVQAEQPSSS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 EVQAEQPSSSSPR 13 0 Q9Y388;A0A1W2PP04 Q9Y388 RBMX2 RNA-binding motif protein, X-linked 2 1 EVQAEQPS(0.002)S(0.067)S(0.608)S(0.323)PR 143.05 2.1159000000000002e-05 0.0 6998.4 5854.0 5292.4 6382.6 7455.1 7037.1 5616.0 5607.6 6995.4 6085.9 True False 6898.60153265062 5840.445422668691 4857.279301254787 6851.997695729437 7016.605675290535 6736.139637281313 5906.769000700959 5868.149567550261 6207.50438717229 7137.839706047985 0.9664831120829661 0.8182371226016754 0.680497111351373 0.9599539885889633 0.9830153049451746 0.9437224587116595 0.8275289504884897 0.8221184292746307 0.8696615002313082 1.0 12.801271787914212 -11.838750678703162 1.9901376256119694 1.5442709568987925 0.8720213814757997 0.15280405731568636 0.08841131302669997 7753784.658623047 898103.8978064045 18984131.074989673 0.023696192563848095 1.4496038083461817e-12 11.838750678703162 -0.6722495754229928 EVQAEQPSSS(ph)SPRR ddPTM_PC-9_Lapatinib_30min_R1 1 EVQAEQPSSSSPRR 14 1 Q9Y388;A0A1W2PP04 Q9Y388 RBMX2 RNA-binding motif protein, X-linked 2 1 EVQAEQPS(0.046)S(0.077)S(0.653)S(0.224)PRR 94.325 0.0015925000000000002 4376200.0 11257.0 12821.0 15988.0 10504.0 9072.1 12860.0 14593.0 9723.0 9993.8 11838.0 True False 11096.473115719027 12791.3137622199 14673.52835546474 11276.499200316797 8538.49691443485 12310.00777812418 15348.554135902607 10174.766075556603 8868.193004620527 13884.182526856515 0.7992168854201425 0.921286776335398 1.0568521644743127 0.8121831572369772 0.6149801688301508 0.8866209987021295 1.1054704953794379 0.7328314832994527 0.638726333903099 1.0 13.761154616182708 EVQAEQPSSSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 5 EVQAEQPSSSSPR 13 0 Q9Y388;A0A1W2PP04 Q9Y388 RBMX2 RNA-binding motif protein, X-linked 2 1 EVQAEQPSSS(0.003)S(0.997)PR;EVQAEQPSSS(0.001)S(0.999)PR;EVQAEQPSS(0.005)S(0.039)S(0.956)PR;EVQAEQPSS(0.008)S(0.084)S(0.907)PR;EVQAEQPS(0.007)S(0.056)S(0.454)S(0.482)PR 273.84 1.4412999999999997e-68 463901900.0 1014264.8 1066209.0 1310811.4 1534649.0 1376677.0 1308808.9 1103731.4 1397905.6 1088656.3 1209332.3 True False 1336779.9083815848 1410840.2083966117 1293429.1843670462 1180859.383140695 1185549.1617247753 1226968.8725825928 1201961.356388959 1181891.4101950102 1146200.4494821134 1166993.9442691046 1.1454900129912997 1.2089524674270948 1.1083426702587809 1.0118813288960762 1.0159000117753756 1.051392664553243 1.0299636620151913 1.0127656754339338 0.9821820028380572 1.0 20.154365643997885 -5.580342706175453 3.2465538026952343 1.0174975678601181 1.1761026498474834 0.8933273797088128 0.022826550187369156 0.06975228952147676 1.488365352983878 0.006479408294109192 0.012813948220548906 2.6281932394877934e-06 5.580342706175453 0.15860508198736523 EVQAEQPSSSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 EVQAEQPSSSSPR 13 0 Q9Y388;A0A1W2PP04 Q9Y388 RBMX2 RNA-binding motif protein, X-linked 2 1 EVQAEQPSSSS(1)PR;EVQAEQPSSS(0.004)S(0.995)PR;EVQAEQPSSS(0.009)S(0.991)PR;EVQAEQPSSS(0.002)S(0.998)PR;EVQAEQPS(0.001)S(0.005)S(0.043)S(0.951)PR;EVQAEQPS(0.004)S(0.012)S(0.1)S(0.885)PR 287.42 6.959199999999998e-83 390497000.0 492501.6 521467.0 605838.0 552262.0 629121.0 530974.4 568398.0 498023.3 503266.6 414241.5 True False 575872.3935300033 573234.7975046568 620283.4755734104 521320.5505975618 505849.2562328851 503129.1677369903 514555.22659484256 484950.7160743039 510625.9219381342 489340.2048160903 1.1768344147124281 1.1714443077901127 1.2675914823032635 1.0653540123348146 1.0337373697364587 1.0281786838383378 1.0515286124675345 0.9910297811244917 1.0434988110777526 1.0 18.90047829574428 -5.895461017239997 5.500569312149578 1.0277577203296648 1.2009023565316417 0.8779991537450953 0.030116313941108093 0.06563454395081432 2.963652671865709 0.008495182956915447 0.012789031943935792 1.2721519347460442e-06 5.895461017239997 0.17314463620197684 EVQAEQPSSSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 5 EVQAEQPSSSSPR 13 0 Q9Y388;A0A1W2PP04 Q9Y388 RBMX2 RNA-binding motif protein, X-linked 2 1 EVQAEQPSSS(0.001)S(0.999)PR;EVQAEQPSSS(0.002)S(0.998)PR;EVQAEQPSS(0.007)S(0.052)S(0.941)PR;EVQAEQPS(0.001)S(0.002)S(0.019)S(0.978)PR;EVQAEQPS(0.001)S(0.006)S(0.048)S(0.944)PR 273.84 1.4412999999999997e-68 415401000.0 1403890.3 1360329.0999999999 1594168.8 1299265.7 1474443.3 1393567.8 1270463.5 1274412.5999999999 1402675.5 1149906.4 True False 1383870.5668800527 1357179.3415473208 1463102.3949335231 1394818.0338013174 1387719.443961059 1333968.153759207 1336241.8836043514 1333626.4618679283 1244691.4143621658 1348666.1890860375 1.0261031069651656 1.0063122754393752 1.0848513937500255 1.034220361634895 1.0289569466418425 0.9891017989137914 0.9907877089362597 0.9888484434919353 0.9229054783420254 1.0 20.36310187762181 -6.927513779770804 1.3812584182528855 0.9705440534758761 1.03942768806973 0.5455374180504144 0.02669657214864361 0.3278862185666116 1.2882804131984962 0.013687154635054688 0.010687069324353078 1.1816428194928926e-07 6.927513779770804 0.06888363459385383 EVQAEQPSSSS(ph)PRR ddPTM_PC-9_AZD4547_30min_R2 1 EVQAEQPSSSSPRR 14 1 Q9Y388;A0A1W2PP04 Q9Y388 RBMX2 RNA-binding motif protein, X-linked 2 1 EVQAEQPS(0.037)S(0.004)S(0.225)S(0.734)PRR 113.05 0.00011264 4919900.0 11147.0 11849.0 20504.0 26247.0 19727.0 14591.0 11910.0 18622.0 12523.0 15707.0 True False 14691.514127996448 15678.957530176023 20232.103562924403 20196.15966210764 16988.246562806376 13678.622463411268 12969.966927272797 15744.397790989215 13184.94021378879 15157.10271083871 0.9692824815055635 1.0344297211210518 1.334826579254926 1.3324551563317932 1.1208109417018222 0.9024562757386216 0.8557022522515526 1.0387471861446538 0.8698852587678486 1.0 13.88770638740046 -6.675174821592353 4.902136335165918 0.9311833811980822 1.1758913705819112 0.47657471618855873 0.11823914987124694 0.19789414248695705 8.23185202234611 0.04358449404028594 0.0431130578869135 2.112638443804475e-07 6.675174821592353 0.24470798938382898 EVQAEQPSSSS(ph)PRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVQAEQPSSSSPRR 14 1 Q9Y388;A0A1W2PP04 Q9Y388 RBMX2 RNA-binding motif protein, X-linked 2 1 EVQAEQPS(0.017)S(0.032)S(0.158)S(0.793)PRR 78.08800000000001 0.035549000000000004 0.0 11276.0 13904.0 17584.0 15151.0 22643.0 12182.0 16998.0 17776.0 15312.0 13108.0 True False 13184.804088848272 15284.297231665198 18003.26924769136 14302.138590204746 18206.266694135535 11543.15447481464 15387.826385137063 17309.398835228854 15535.90903254199 15484.3766371291 0.8514907895764551 0.9870786270475918 1.1626731685486358 0.9236496195727032 1.1757829921599665 0.7454710477098556 0.9937646665245454 1.1178621678397849 1.0033280251843864 1.0 13.918525684381558 -4.788162807504869 4.65072567362861 1.0151912809132488 0.8427951743947585 0.14503719745856736 0.11840785955758369 0.34221886566467113 16.331079183201698 0.029065065530685896 0.18340218447179546 1.6286853596548242e-05 4.788162807504869 -0.17239610651849036 EVQAEQPSSSS(ph)PRR ddPTM_PC-9_Lapatinib_30min_R1 1 EVQAEQPSSSSPRR 14 1 Q9Y388;A0A1W2PP04 Q9Y388 RBMX2 RNA-binding motif protein, X-linked 2 1 EVQAEQPS(0.344)S(0.129)S(0.129)S(0.398)PRR 81.643 0.0046662 4122900.0 18749.0 15983.0 15374.0 14125.0 15805.0 16321.0 17112.0 15091.0 22300.0 15993.0 True False 18481.635821854503 15945.992345492587 14110.009065356197 15163.7996196187 14875.38097382556 15622.988876109248 17997.975630340963 15792.182952404064 19788.339170589556 18757.368740667025 0.985300021414266 0.8501188288163671 0.752238187585709 0.8084182717346028 0.793041986831282 0.8328987446004478 0.9595149447225156 0.8419188837593051 1.0549634889720607 1.0 14.195169842208983 -7.957305109714132 1.1385747787679095 1.019818344012855 0.8333176972728832 0.44708052622459693 0.072619945653789 0.45688820321072726 1.0746443930188416 0.06690161893520798 0.024013835776764587 1.1033032317195253e-08 7.957305109714132 -0.1865006467399718 EVQHNCQLHR ddPTM_PC-9_AZD4547_30min_R2 2 EVQHNCQLHR 10 0 Q9UBP9-2;Q9UBP9-4;Q9UBP9 Q9UBP9-2 GULP1 PTB domain-containing engulfment adapter protein 1 0 ; 114.97 0.00048936 1476460.0 1464.54 2915.41 4660.8 5328.0 3775.34 3256.3 3094.41 3690.75 3222.1000000000004 4032.2 False True 1930.2332556756005 3857.7592685501327 4598.994746687378 4099.711916779421 3251.199208111998 3052.6830462344014 3369.806495333517 3120.429392497769 3392.4136279524773 3891.033905306159 0.49607207304037193 0.9914483816985892 1.1819467161197905 1.0536304788268973 0.8355617779835777 0.7845429056969903 0.8660439814564839 0.8019537913155871 0.8718540394434192 1.0 11.925937836240895 -6.305049748972294 24.39607273272776 0.8466204706416811 0.9530492430273653 0.028712128303851836 0.17416187725895588 1017.1986840576351 569028.003947119 0.05593150787739726 0.06342084204147141 4.953934396206075e-07 6.305049748972294 0.10642877238568416 EVQHNCQLHR ddPTM_PC-9_Lapatinib_30min_R1 2 EVQHNCQLHR 10 0 Q9UBP9-2;Q9UBP9-4;Q9UBP9 Q9UBP9-2 GULP1 PTB domain-containing engulfment adapter protein 1 0 ; 132.01 6.760699999999999e-05 973400.0 1909.3899999999999 1580.89 2094.8999999999996 3579.1 3541.1000000000004 3654.7000000000003 1841.56 2909.75 5555.2 4698.700000000001 False True 1882.1617484607582 1577.229546334593 1922.665408547852 3842.3189535275974 3332.8194600704633 3498.39700052181 1936.9069659777158 3044.947607564622 4929.51487715063 5510.864034375799 0.34153659693292465 0.28620367631937804 0.3488863808931964 0.6972262297817345 0.6047725799948833 0.63481823879149 0.3514706503182861 0.5525354261275138 0.8945085283180977 1.0 12.428062817684154 -8.813030622029823 0.11809959679197297 1.472487148000564 1.0196599824404009e-15 0.6408308381174985 0.13945658318519644 10.23649301008661 0.654452809945683 4.574151708893492 2.9367171536928525 1.5380461891052589e-09 8.813030622029823 -1.4724871480005628 EVQT(ph)TPSTASNK ddPTM_PC-9_AZD4547_30min_R2 1 EVQTTPSTASNK 12 0 Q7L5N7-2;Q7L5N7 Q7L5N7-2 LPCAT2 Lysophosphatidylcholine acyltransferase 2 1 EVQT(0.693)T(0.272)PS(0.026)T(0.006)AS(0.003)NK 153.75 0.00056681 2324600.0 20681.0 21345.0 28517.0 31356.0 27383.0 23099.0 26252.0 34532.0 24494.0 23122.0 True False 27257.12780847714 28244.353825774935 28138.84594732319 24127.35864537079 23581.343114985906 21654.615878441302 28588.37714313729 29195.872866418187 25788.702834507912 22312.505817789064 1.2216076504838773 1.2658530626917124 1.2611244195122613 1.0813379206442515 1.0568666427499702 0.9705147442998874 1.281271470654124 1.3084981626376195 1.155795904104477 1.0 14.445564924861241 -5.748644718923774 24.591587930184048 1.1325002322187026 1.2511609009440143 0.23770780062805585 0.10342775914023414 331.28104679072277 636721.8845366804 0.03110207825683046 0.05341454754481351 1.7838374655474751e-06 5.748644718923774 0.11866066872531178 EVQT(ph)TPSTASNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVQTTPSTASNK 12 0 Q7L5N7-2;Q7L5N7 Q7L5N7-2 LPCAT2 Lysophosphatidylcholine acyltransferase 2 1 EVQT(0.967)T(0.033)PSTASNK 107.39 0.0016822 0.0 28699.0 27199.0 24708.0 19413.0 33117.0 22510.0 24501.0 21766.0 19542.0 16734.0 True False 33557.173868912454 29899.13696807118 25297.132425611802 18325.35254779519 26627.961582373657 21329.535973409736 22180.087908121164 21194.66556298331 19827.764780168218 19767.741733728883 1.6975724552114737 1.5125216309891136 1.2797178740173618 0.9270331833872252 1.3470411512378 1.0790072159338275 1.1220344846106622 1.0721844633785218 1.0030364139337635 1.0 14.270860446588266 -5.246585239934917 1.9995345620981684 1.0934497350873815 1.6859307695653616 0.7853782076149017 0.10996494645578656 0.16578030086643636 1.1847188361719545 0.03030030303851114 0.12461860840697549 5.667803173837245e-06 5.246585239934917 0.5924810344779801 EVQTNDLK ddPTM_PC-9_Lapatinib_30min_R1 2 EVQTNDLK 8 0 D6RAT0;P61247;D6RG13;D6R9B6;D6RB09;H0Y9Y4;E9PFI5 D6RAT0 RPS3A 40S ribosomal protein S3a 0 ; 127.68 0.00012074 0.0 187115.0 156429.0 222240.0 172909.0 174760.0 195510.0 180866.0 168392.0 205272.0 168838.0 False True 184446.70578731128 156066.79826146938 203968.2850712089 185625.30466751478 164480.96039137954 187148.49305607012 190230.35649586553 176216.1070652193 182152.10575001166 198021.4233375059 0.9314482376633664 0.7881308781195384 1.0300314058624214 0.9374001132753031 0.8306220489640643 0.9450921516562172 0.9606554345972893 0.8898840544382826 0.9198606023528741 1.0 17.595296993988327 -14.522878745280334 0.2268521752959727 1.4477015213711375 0.9044311470898072 0.1392809935230046 0.06387227298058872 333.3087882537812 3.3280537878923884 68.51150173350409 0.11408566250004447 3.000000000000026e-15 14.522878745280334 -0.5432703742813303 EVQVEHIK ddPTM_PC-9_AZD4547_30min_R2 3 EVQVEHIK 8 0 Q96DG6 Q96DG6 CMBL Carboxymethylenebutenolidase homolog 0 ;; 119.68 0.0028945999999999998 5462500.0 65268.0 68299.0 93367.0 120331.0 105024.0 90518.0 80313.0 100453.0 79179.0 91666.0 False True 86021.86634126422 90375.31609026018 92128.89257508598 92590.54704541754 90443.23044619926 84857.89515064505 87460.70141310341 84930.2970302994 83364.24029286779 88456.80124095909 0.9724731748657514 1.021688720622793 1.0415128207510467 1.046731802941845 1.0224564892396355 0.9593145350066355 0.9887391380438654 0.9601330348691518 0.9424288367129736 1.0 16.432685452248997 -6.754534197233667 24.666676189843106 0.9687949236408836 1.023584589172999 0.5294863188800775 0.023887369829236456 107.12163626200055 382659.19368653366 0.008218366797994451 0.008039760429508951 1.7598100873085404e-07 6.754534197233667 0.054789665532115506 EVQVEHIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EVQVEHIK 8 0 Q96DG6 Q96DG6 CMBL Carboxymethylenebutenolidase homolog 0 ;; 82.749 0.013452 6557000.0 65088.0 69295.0 71566.0 84031.0 94526.0 81350.0 77555.0 67051.0 71752.0 60184.0 False True 76106.11285340172 76174.14964529914 73272.40485556624 79323.01550217776 76004.30886056882 77083.86279150959 70208.42895042402 65290.98229640698 72801.23725855243 71094.88278371819 1.0704865086412545 1.0714434944218543 1.0306283938672833 1.1157345282288578 1.0690545632065516 1.0842392556720406 0.9875313974988762 0.9183640191802892 1.0240010871109422 1.0 16.117458101866212 -7.309112338416524 5.519473489735062 0.9744295546491444 1.0732994528165698 0.6611248250719748 0.031813200519616 0.11772001394083277 8.705844789097775 0.012987487588112445 0.008776504411707383 4.907809100411962e-08 7.309112338416524 0.09886989816742542 EVRS(ph)PTKAPHLQLIEGK ddPTM_PC-9_AZD4547_30min_R2 1 EVRSPTKAPHLQLIEGK 17 2 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 EVRS(0.821)PT(0.179)KAPHLQLIEGK 46.156000000000006 0.034968 8335600.0 59083.0 42626.0 69954.0 113840.0 96884.0 63997.0 51766.0 74134.0 57866.0 66901.0 True False 77870.16499725598 56404.02090313813 69026.3642528684 87595.94681046731 83433.32893957179 59995.2574731637 56373.07371597005 62678.29372984617 60924.67862421963 64558.816353079645 1.2061894780005729 0.8736842477820226 1.0692012052289686 1.356839418049348 1.292361503086817 0.9293116085809673 0.8732048835539237 0.9708711725297335 0.943708110926562 1.0 15.978326507465075 -6.787493538669281 24.951998935470957 0.9372100891356453 1.149697356937931 0.4231867353970771 0.12585391079199076 250.19509473096096 239609.33303124658 0.04934938949215656 0.043535841208811786 1.6311971776136184e-07 6.787493538669281 0.21248726780228566 EVS(ph)DDEAEEK ddPTM_PC-9_Lapatinib_30min_R1 1 EVSDDEAEEK 10 0 P07900;P07900-2;G3V2J8 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 EVS(1)DDEAEEK 150.06 1.5725e-08 0.0 10052.0 17327.0 8194.8 9775.3 10762.0 12608.0 12564.0 15678.0 11669.0 11649.0 True False 9908.65663668896 17286.8803960677 7521.055176842779 10494.208171444865 10129.000318906077 12068.785230683488 13214.502443875865 16406.45711535291 10354.714339982489 13662.514128683182 0.7252440175623792 1.2652781349938733 0.550488373223565 0.7681022740472961 0.7413716262983531 0.883350247034416 0.9672086937596092 1.2008373393670697 0.7578923060905551 1.0 13.737935367367626 -7.169976102454714 3.3243894115730117 0.9996335180903788 0.8187688962309545 0.13976475754125883 0.19723296505670526 0.5079656674135377 10.718057289772549 0.08156154075341666 0.060314321418519265 6.7612017864628e-08 7.169976102454714 -0.1808646218594243 EVS(ph)DSEAGGGPQGER ddPTM_PC-9_AZD4547_30min_R2 1 EVSDSEAGGGPQGER 15 0 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 EVS(0.939)DS(0.061)EAGGGPQGER 137.27 2.9713e-06 0.0 1676.8 1426.2 2465.4 2967.8 2075.7 4901.1 5624.3 5855.3 1771.5 2207.2 True False 2209.98752039333 1887.1912591389205 2432.7071851362566 2283.6195620529234 1787.5248841900543 4594.633442219518 6124.851804287186 4950.4979264085 1865.1378734110713 2129.9265998193923 1.037588581963682 0.8860358189333591 1.1421554082392036 1.0721588069028123 0.8392424810984698 2.157179239232526 2.8756163732621323 2.324257524568348 0.8756817599109876 1.0 11.056587998727675 -6.761403645089902 24.9999982347118 1.9936300006740064 1.0017717718155872 0.34609787526644775 0.5671708516412217 0.9752003245722997 681981.6163543971 0.1962173660821662 0.18435250189137098 1.7321933018448157e-07 6.761403645089902 -0.9918582288584192 EVS(ph)DSEAGGGPQGER ddPTM_PC-9_Lapatinib_30min_R1 1 EVSDSEAGGGPQGER 15 0 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 EVS(0.508)DS(0.492)EAGGGPQGER 72.797 0.018908 5488900.0 2524.9 5964.1 2461.1 1945.7 7814.5 4497.8 5592.0 8254.1 6251.1 6066.6 True False 2488.894462990049 5950.290492883215 2258.757858120732 2088.7932686649287 7354.866473898122 4305.439578883898 5881.526398133858 8637.615619073513 5547.035290998762 7115.203726763622 0.3497994658435637 0.8362783022644001 0.3174551207331539 0.293567598185277 1.0336831883299442 0.6051041887513521 0.8266139135286703 1.2139660297544796 0.7796031574097813 1.0 12.79668935011149 -6.736289874506729 1.0496887752857027 0.9766245673593194 0.4832711907404063 0.4397887253686157 0.2298507341809576 0.4999641708256125 1.1790174446366881 0.12644896596150695 0.11757575748034753 1.8353129351484138e-07 6.736289874506729 -0.49335337661891304 EVS(ph)GHSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVSGHSVR 8 0 Q9NWH9;Q9NWH9-3;H7C3F4 Q9NWH9 SLTM SAFB-like transcription modulator 1 EVS(0.999)GHS(0.001)VR 77.533 0.023407 2481800.0 24536.0 32891.0 30326.0 27460.0 32600.0 32987.0 32201.0 28672.0 30191.0 28422.0 True False 28689.46019191037 36156.20111095369 31049.086851995457 25921.50522652119 26212.26402105811 31257.103649705332 29150.688164948733 27919.39038049514 30632.486259239507 33574.683611571796 0.8544968144397437 1.0768888109043016 0.9247767517694233 0.7720550855045771 0.7807151460996592 0.9309723960863271 0.868234188062511 0.8315607885839463 0.9123685754906642 1.0 15.035086184141347 -5.527111982471046 24.958716871896463 0.8613858721916109 0.9744778122287362 0.17480740875677792 0.08183094756423867 146.50509222854416 863775.4553577772 0.021368606495018008 0.0372060873024163 2.9708998889015503e-06 5.527111982471046 0.1130919400371253 EVS(ph)PAPAVAGQSK ddPTM_PC-9_AZD4547_30min_R2 4 EVSPAPAVAGQSK 13 0 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 EVS(1)PAPAVAGQSK;EVS(1)PAPAVAGQSK;EVS(1)PAPAVAGQSK;EVS(1)PAPAVAGQSK 145.86 4.9142e-05 111180800.0 176151.0 175079.0 222248.0 314586.0 256578.0 243745.0 221323.0 258984.0 201986.0 221759.0 True False 232163.35383158774 231669.86289355156 219300.84630573657 242063.05800524962 220956.57355866188 228503.58661806496 241020.3182405371 218963.9736602703 212662.56759740846 213995.28490818685 1.084899388933713 1.0825933057027302 1.024792889244387 1.1311607080927275 1.0325301029574634 1.0677972961698796 1.1262879850083853 1.023218683319192 0.9937722117973292 1.0 17.70721948361222 -7.956102180864026 8.403699024466043 1.0006484646623832 1.0764985434130516 0.5288167431173503 0.03210380477563837 0.19130325664995104 33.083834078251684 0.017124079115095357 0.008157696515937504 1.1063634480122977e-08 7.956102180864026 0.0758500787506684 EVS(ph)PAPAVAGQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EVSPAPAVAGQSK 13 0 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 EVS(1)PAPAVAGQSK;EVS(1)PAPAVAGQSK;EVS(1)PAPAVAGQSK 141.59 6.9292e-05 64096000.0 116394.0 138815.0 155539.0 153252.0 173519.0 138462.0 154177.0 139189.0 125505.0 103043.0 True False 136097.20531371125 152595.6358036249 159247.6396449422 144665.7872896879 139519.1975665635 131200.80897157986 139572.23841518303 135535.4362329358 127340.27319286727 121723.88021206109 1.1180813910681264 1.2536211919779474 1.3082694978792093 1.1884749897691282 1.1461941348197273 1.0778559535155186 1.1466298820907406 1.1134662811998182 1.0461404366260885 1.0 16.893252703161025 -6.382497789365122 2.0982558894721786 1.087876690708439 1.2299296049491564 0.5597660495986665 0.058264461188167894 0.2555206378405324 2.214919858212379 0.020752282344552866 0.0246424996139247 4.1447869380162045e-07 6.382497789365122 0.14205291424071742 EVS(ph)PAPAVAGQSK ddPTM_PC-9_Lapatinib_30min_R1 2 EVSPAPAVAGQSK 13 0 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 EVS(1)PAPAVAGQSK;EVS(1)PAPAVAGQSK 104.9 0.0012878 124271000.0 225080.0 201928.0 237090.0 206150.0 206659.0 192010.0 220104.0 199612.0 194304.0 185211.0 True False 221870.31792538275 201460.44812241956 217597.37539386668 221310.95869624082 194503.72392722676 183798.17989717145 231499.90814285702 208886.70223943228 172419.43740817183 217224.47457185492 1.0213872923973446 0.927429786719448 1.0017166611761714 1.0188122638226667 0.8954042785031 0.846120955106159 1.0657174270953524 0.9616167913451915 0.7937385405028926 1.0 17.728827134458577 -6.260160454453226 24.968349413940338 0.9280624578553834 0.988370318117249 0.15113741328221608 0.075486676502444 258.0430154709505 5037734.056715095 0.023264180497449376 0.028345675515168554 5.493378779704698e-07 6.260160454453226 0.06030786026186552 EVS(ph)PEVVR ddPTM_PC-9_AZD4547_30min_R2 4 EVSPEVVR 8 0 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 EVS(1)PEVVR;EVS(1)PEVVR;EVS(1)PEVVR;EVS(1)PEVVR 109.44 0.003778 353097800.0 366393.0 332130.0 451292.0 640767.0 529411.0 472400.0 432691.0 524347.0 385627.0 419254.0 True False 482898.3525521656 439484.52734385733 445307.5732110457 493048.06790146395 455911.42094904964 442860.75332160044 471199.6607664656 443321.2194453781 406010.4559468762 404576.0450709853 1.1935910651048018 1.0862841057896722 1.1006770634008096 1.2186783520881859 1.1268868399488587 1.094629201894289 1.1646751371149293 1.0957673466989246 1.0035454666517372 1.0 18.626051374954827 -8.158255710889453 2.995055764307695 0.997956551229049 1.1377505829754977 0.6444158211255611 0.04069362614308385 0.1697850807759887 2.7309483972587936 0.03442540167857481 0.01081018201617653 6.946152104457483e-09 8.158255710889453 0.13979403174644867 EVS(ph)PEVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EVSPEVVR 8 0 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 EVS(1)PEVVR;EVS(1)PEVVR;EVS(1)PEVVR;EVS(1)PEVVR 123.86 0.0032982 260834000.0 415262.0 409791.0 517250.0 534209.0 561083.0 475919.0 508689.0 455618.0 408745.0 331031.0 True False 485557.65480164066 450472.3422656297 529583.2016815484 504279.00165894534 451142.8139180162 450960.96983248333 460502.2953305677 443658.51026717474 414722.1223554321 391044.2998600452 1.241694751657093 1.1519726599437807 1.3542793025523867 1.289570009943699 1.1536872269445695 1.1532222052434529 1.177621807798711 1.1345479538404222 1.0605502305080554 1.0 18.57697252843527 -7.869692316840165 0.5396488237787855 0.9982693897574411 1.2544640728560457 0.6737211372907783 0.05609293042558997 0.5333567126788762 0.3551724716117009 0.06085951258802991 0.03649115073102215 1.3499189164348333e-08 7.869692316840165 0.2561946830986046 EVS(ph)PEVVR ddPTM_PC-9_Lapatinib_30min_R1 3 EVSPEVVR 8 0 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 EVS(1)PEVVR;EVS(1)PEVVR;EVS(1)PEVVR 120.99 0.0033918 291578000.0 1035632.0 854739.0 872219.0 776054.0 852259.0 786224.0 784782.0 734292.0 837656.0 585267.0 True False 1020863.6977683505 852759.904360509 800508.5206827044 833127.6000002536 802130.8012256618 752599.0322976594 825414.1719921839 768409.8869847382 743310.3603712713 686429.6211307424 1.4872081074920707 1.2423122168821532 1.1661916910928787 1.2137116091054732 1.1685550514331347 1.0963964973683937 1.2024745823650427 1.1194299653312618 1.082864633881665 1.0 19.38875228446595 -1.5228787452803394 0.6842628226247218 1.1216810952356602 40.6393310795169 0.7978591144948264 0.055553074364187376 114.74225078417189 0.6484334874590193 0.021755686412156052 6917.589310287734 0.029999999999999874 1.5228787452803394 39.51764998428124 EVS(ph)PGSRDILDGVR ddPTM_PC-9_AZD4547_30min_R2 1 EVSPGSRDILDGVR 14 1 Q96RL1-2;Q96RL1-3;Q96RL1;Q96RL1-4 Q96RL1-2 UIMC1 BRCA1-A complex subunit RAP80 1 EVS(0.977)PGS(0.023)RDILDGVR 59.15 0.028626 3641300.0 13018.0 7569.7 18641.0 35260.0 25948.0 14642.0 11577.0 16883.0 11533.0 14090.0 True False 17157.453208778832 10016.457491448513 18393.808160186964 27131.351761569516 22345.56809508287 13726.433425349036 12607.330572379275 14274.12028274465 12142.610834913845 13596.713388662225 1.261882391599559 0.7366822558605118 1.3528128183921897 1.9954345573095116 1.6434536388562824 1.0095405435842297 0.927233678610306 1.0498213704090644 0.8930548499344775 1.0 13.730970343458765 -6.861841868937378 8.047566998184898 0.9720619674460905 1.3912767243032598 0.3336806940092458 0.29847034533695976 0.35229437280627457 25.149013672119487 0.1210284989199458 0.10680633501815011 1.3745423688424034e-07 6.861841868937378 0.41921475685716925 EVS(ph)PLLPK ddPTM_PC-9_AZD4547_30min_R2 1 EVSPLLPK 8 0 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 EVS(1)PLLPK 82.749 0.016028 6570600.0 88029.0 93721.0 112070.0 119610.0 131520.0 131440.0 107470.0 136140.0 109600.0 110260.0 True False 116020.39088305346 124014.4804359547 110583.87857476287 92035.76245607862 113260.71820045098 123221.03602157348 117034.62180302352 115102.69118597743 115393.23224716546 106399.83096053213 1.0904189399143875 1.1655514798886901 1.0393238182472562 0.8649991416830192 1.0644821253754042 1.1580942836956292 1.0999512005468906 1.0817939290587175 1.0845245824682685 1.0 16.69913633324024 -6.524579822377716 24.998309646107614 1.0931896424852834 1.0384522967764072 0.06199798712818683 0.07879662241655647 154.9996426357516 2277760.646793649 0.02806862987132611 0.028270558790586188 2.9882723585457637e-07 6.524579822377716 -0.05473734570887623 EVS(ph)PLLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVSPLLPK 8 0 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 EVS(1)PLLPK 80.755 0.01885 4712100.0 86902.0 93406.0 86191.0 93177.0 110990.0 80132.0 101150.0 70637.0 68491.0 70972.0 True False 101612.79220726273 102678.73038125147 88246.12032118758 87956.59477390992 89242.3062483815 75929.73685567609 91568.33973741712 68782.8535960881 69492.55130275834 83838.66178595697 1.2120039853055353 1.2247181454708074 1.052570716675834 1.0491173511150045 1.0644528949689134 0.9056649430966273 1.0921970578585127 0.8204192687580477 0.8288843097254492 1.0 16.355328068631735 -5.423872297444631 0.4695811791834991 0.8987821796534469 1.3519968059864704 0.6337146099820878 0.0806214040614577 1.7615695699470064 0.4652514120195603 0.06156343604048526 0.4165168339696073 3.768145835163853e-06 5.423872297444631 0.45321462633302356 EVS(ph)PLLPK ddPTM_PC-9_Lapatinib_30min_R1 1 EVSPLLPK 8 0 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 EVS(1)PLLPK 76.465 0.024918 7619900.0 94819.0 117400.0 130410.0 119380.0 120030.0 133700.0 122110.0 116290.0 122680.0 98994.0 True False 93466.86367232517 117128.16751303468 119688.19319715745 128159.60344000577 112970.07138805962 127981.9626699226 128432.25831118129 121693.25793751715 108862.48652232859 116104.98099878643 0.8050202744816101 1.0088125979216942 1.0308618301088088 1.1038251962794372 0.9729993529669534 1.1022951949947808 1.1061735440318767 1.0481312420075166 0.9376211561799098 1.0 16.82507034076692 -4.728100869195356 2.858265055056314 1.043754197623656 0.7424345795170758 0.6197736449320479 0.05416522869639898 0.3409179893372793 3.4076447678797797 0.013919875759076102 0.25711492301547234 1.8702477063612825e-05 4.728100869195356 -0.30131961810658014 EVS(ph)PSDVR ddPTM_PC-9_AZD4547_30min_R2 1 EVSPSDVR 8 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 EVS(0.992)PS(0.008)DVR 112.11 0.0037351999999999997 23505000.0 194950.0 307370.0 316770.0 234400.0 252720.0 257500.0 238530.0 334010.0 240250.0 233500.0 True False 256940.0447880961 406721.3415520469 312569.42282615916 180362.70144389945 217634.19026473459 241398.48429363352 259758.70790616164 282396.4292862368 252949.1245199042 225325.23607186906 1.1403074474363062 1.8050412312552522 1.38719225718003 0.8004549538622097 0.9658669133506139 1.0713335465745957 1.1528167569446583 1.2532836277431636 1.122595626347083 1.0 17.781649376633517 -5.5786063909985755 8.229152244063803 1.0654338002728192 1.5032673015951932 0.47831488155112933 0.18802526285771604 0.19800849665553413 26.096531013663178 0.0509728416989572 0.08868042690563283 2.6387218240773076e-06 5.5786063909985755 0.437833501322374 EVS(ph)PSDVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVSPSDVR 8 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 EVS(0.986)PS(0.014)DVR 102.62 0.0042228000000000005 7834300.0 73166.0 91886.0 75286.0 83979.0 92622.0 55643.0 75240.0 55141.0 64052.0 54589.0 True False 85551.5587056292 101007.83482658144 77081.10376374496 79273.92889359163 74473.3839925902 52724.98312609679 68112.72250957265 53693.60717671885 64988.639325521166 64485.55357371374 1.3266778986061554 1.5663637703151436 1.1953235956272468 1.2293285007311479 1.1548847744240782 0.817624726844077 1.0562477754294637 0.8326455182762978 1.0078015264493674 1.0 15.976688375404159 -6.0371124895222765 1.0131286840088753 0.9363555432410026 1.4416303892916107 0.7337731100791557 0.11136373068229466 0.267448571173738 0.5613895158047791 0.04500730204692382 0.09129544327301577 9.180947638102359e-07 6.0371124895222765 0.5052748460506081 EVS(ph)PSDVR ddPTM_PC-9_Lapatinib_30min_R1 1 EVSPSDVR 8 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 EVS(0.961)PS(0.039)DVR 91.087 0.008988 24014000.0 52933.0 85366.0 76485.0 61691.0 63310.0 80552.0 94517.0 97319.0 75339.0 68180.0 True False 52178.16571327666 85168.3402718713 70196.69854063811 66227.96193514313 59586.230272249 77106.9787358834 99410.62778476707 101840.79602047655 66853.52846515905 79964.82215586067 0.6525139968619625 1.0650725903681544 0.8778447403261479 0.8282137088488384 0.7451555404713907 0.9642612420945924 1.2431795019940677 1.273569968329037 0.8360367304369639 1.0 16.287077853765304 -7.0135860462220725 7.63355511011834 1.1104415016153812 0.8490348966577963 0.38093727146163714 0.15135769555391992 0.16430282349369849 57.89894854464822 0.055505226027248215 0.04540974695528412 9.692012236507549e-08 7.0135860462220725 -0.26140660495758494 EVS(ph)SRPSTPGLSVVSGISATSEDIPNKIEDLR ddPTM_PC-9_AZD4547_30min_R2 2 EVSSRPSTPGLSVVSGISATSEDIPNKIEDLR 32 2 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 EVS(0.288)S(0.288)RPS(0.288)T(0.131)PGLS(0.002)VVSGIS(0.001)ATSEDIPNKIEDLR;EVS(0.234)S(0.234)RPS(0.234)T(0.234)PGLS(0.05)VVS(0.005)GIS(0.005)AT(0.003)S(0.001)EDIPNKIEDLR 47.979 0.0039705999999999995 7002400.0 6856.4 6004.5 10133.7 10583.3 8987.4 6194.77 6529.400000000001 8594.7 6205.8 8347.2 True False 9036.592578020527 7945.337200602751 9999.320516758044 8143.483695355045 7739.654643816388 5807.410052612311 7110.503950876148 7266.586601558105 6533.825918608201 8054.9670686899435 1.121865862511867 0.9863897807213479 1.2413856483195194 1.0109890736871128 0.9608549082591299 0.7209725381977043 0.8827477369231005 0.9021249298217106 0.8111548890132037 1.0 12.975662975402146 -6.28276822076943 2.596855129657886 0.8592157012974785 1.1024393428884285 0.575930130215562 0.0918025134688083 0.19490630304494602 2.603634520117682 0.029066898821237218 0.036176164086897764 5.214729424789773e-07 6.28276822076943 0.24322364159095 EVS(ph)SRPSTPGLSVVSGISATSEDIPNKIEDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVSSRPSTPGLSVVSGISATSEDIPNKIEDLR 32 2 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 EVS(0.417)S(0.417)RPS(0.073)T(0.073)PGLS(0.018)VVS(0.003)GISATSEDIPNKIEDLR 41.89 0.014436000000000001 3058600.0 1216.2 2103.5 2333.4 2360.8 2255.6 2092.4 2634.1 911.73 1878.5 1951.2 True False 1422.0786389550615 2312.321578452801 2389.0371054687794 2228.5320298168685 1813.6313719600826 1982.6708605403178 2384.5789787674744 887.7980535577864 1905.9695087271505 2304.937114309298 0.6169706887561678 1.0032037594855232 1.0364868918277117 0.9668515535551497 0.7868463571959788 0.8601843617475216 1.034552727692114 0.3851723537471979 0.8269073793357252 1.0 11.170511674747619 EVS(ph)SRPSTPGLSVVSGISATSEDIPNKIEDLR ddPTM_PC-9_Lapatinib_30min_R1 2 EVSSRPSTPGLSVVSGISATSEDIPNKIEDLR 32 2 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 EVS(0.29)S(0.29)RPS(0.232)T(0.187)PGLS(0.001)VVSGISATSEDIPNKIEDLR;EVS(0.249)S(0.249)RPS(0.249)T(0.249)PGLS(0.003)VVSGISATSEDIPNKIEDLR 64.289 2.6422e-05 7240400.0 15988.5 19454.5 18089.4 14692.2 15656.7 21034.0 17478.0 17125.2 20348.3 17606.5 True False 15760.501058068197 19409.454300530906 16602.159359103312 15772.713399742432 14735.803688256532 20134.424852648845 18382.925319489208 17920.89931061625 18056.460176901677 20649.760065813414 0.7632292582498525 0.9399360689262493 0.8039880030659009 0.7638206618126693 0.7136065330198341 0.9750440096387497 0.8902246447852413 0.8678502439495694 0.8744150110874626 1.0 14.333837398294794 -6.770000781709827 24.99987382609627 0.9112922798820751 0.8034159015368824 0.45551366212369226 0.06746178477602002 213.3269637891563 622925.4203704416 0.02459499258143365 0.02202615109241253 1.6982405957050676e-07 6.770000781709827 -0.1078763783451927 EVS(ph)TYIK ddPTM_PC-9_AZD4547_30min_R2 2 EVSTYIK 7 0 Q5VTE0;P68104;A0A087WVQ9;A0A087WV01 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 1 EVS(0.988)T(0.012)YIK;EVS(0.998)T(0.002)YIK 106.6 0.010031 15952800.0 51782.0 72227.0 60639.0 70119.0 68225.0 81777.0 68370.0 88486.0 70324.0 70041.0 True False 68247.59886749016 95572.96527403368 59834.88723918127 53954.14787775076 58753.13639922267 76663.47126244816 74454.79754976006 74812.52190599657 74041.18307070858 67588.8859088211 1.0097458768525593 1.4140337422185612 0.885277016104391 0.7982695254148159 0.8692721533904545 1.1342615021923703 1.101583441546902 1.1068760921273406 1.095463878049296 1.0 16.044498413594418 -9.746952832800323 15.674107599503657 0.9999999684653368 1.0457036222554386 0.0069682502479276875 0.16499443463423574 0.0 0.0 0.1712988981432104 0.04154608532919868 1.7908003360144153e-10 9.746952832800323 0.04570365379010177 EVS(ph)TYIK ddPTM_PC-9_Lapatinib_30min_R1 1 EVSTYIK 7 0 Q5VTE0;P68104;A0A087WVQ9;A0A087WV01 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 1 EVS(0.984)T(0.016)YIK 85.73100000000001 0.019088 4361900.0 25175.0 30546.0 28881.0 23777.0 29394.0 29406.0 30926.0 34969.0 29161.0 27527.0 True False 24815.999883470417 30475.272613740628 26506.51566388399 25525.639897746812 27665.102710827483 28148.373928734036 32527.19695791984 36593.787400610774 25876.581101056574 32285.00527257809 0.7686540446238792 0.9439451025775549 0.8210163027725389 0.790634527770312 0.8569025303621488 0.8718714366338486 1.0075016771190513 1.1334607843998845 0.8015046267635384 1.0 14.978576642246347 -7.170502835179966 3.947069049701537 0.9967749100569608 0.8410305623291822 0.3946250885560665 0.08726424716922386 0.2332133739555004 6.651315419731994 0.034003407531078625 0.025592566838735762 6.753006454538923e-08 7.170502835179966 -0.15574434772777868 EVS(ph)VMRDEDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVSVMRDEDK 10 1 Q96Q89-3;Q96Q89;Q96Q89-2;Q96Q89-4 Q96Q89-3 KIF20B Kinesin-like protein KIF20B 1 EVS(1)VMRDEDK 104.44 0.014512 0.0 9164.0 12813.0 9070.7 13825.0 13536.0 12618.0 12501.0 12295.0 9532.8 9929.2 True False 10715.284202749699 14084.989961833011 9286.979888821312 13050.430071254741 10883.717968989034 11956.289867280504 11316.814780597637 11972.269277629324 9672.199165714232 11729.28536049605 0.9135496216025674 1.2008395677089516 0.791777129073834 1.1126364198801297 0.9279097263372187 1.0193536519751665 0.964834125249642 1.0207160035471248 0.8246196480384018 1.0 13.517827495364616 -8.227457698110133 24.967514291313083 0.9123096465788711 0.9957399823906217 0.07774729897277322 0.11234027945046136 1307.7629076961139 960861.2646025204 0.06892469503066564 0.02604806470599647 5.923007763542311e-09 8.227457698110133 0.08343033581175052 EVSDS(ph)EAGGGPQGER ddPTM_PC-9_Lapatinib_30min_R1 1 EVSDSEAGGGPQGER 15 0 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 EVS(0.183)DS(0.817)EAGGGPQGER 108.66 0.0037845999999999995 0.0 3804.2 5318.3 1509.2 3050.8 3522.7 3902.7 4623.7 4743.6 5516.6 3481.1 True False 3749.951410395163 5305.985803105378 1385.1194016804718 3275.1660091704607 3315.5017118946716 3735.790618638046 4863.092562062145 4964.004973363187 4895.262415626651 4082.8034967258145 0.9184746249488664 1.2995937245964664 0.3392569352875449 0.8021855599459943 0.8120649731375813 0.9150062259018702 1.1911159981032835 1.2158324487926122 1.1989953519811531 1.0 11.995344417710996 -7.154658733673899 3.5687848001540714 1.17042966588089 0.832892778084189 0.30814670732173866 0.22441224291493847 0.31149366603214174 7.303238846550858 0.09463723759041923 0.07105668063100071 7.00392144295729e-08 7.154658733673899 -0.3375368877967009 EVSFQS(ph)TGESEWK ddPTM_PC-9_Lapatinib_30min_R1 1 EVSFQSTGESEWK 13 0 I3L3Q7;I3L3B0;Q07021 I3L3Q7 C1QBP Complement component 1 Q subcomponent-binding protein, mitochondrial 1 EVS(0.001)FQS(0.521)T(0.422)GES(0.056)EWK 114.64 0.0010796 0.0 7620.2 9201.5 7956.0 6080.5 8153.2 7584.3 7865.3 7352.9 7375.4 4541.1 True False 7511.534550626468 9180.194492088474 7301.888391048125 6527.680253953377 7673.64480580794 7259.937168866813 8272.526748791528 7694.542577081159 6544.704785594896 5326.0230843646 1.4103458493594947 1.723649024173105 1.370983241226272 1.2256199702018633 1.4407832418780089 1.363106590765543 1.5532277306639666 1.4447069521102396 1.2288164512106476 1.0 12.378842966238432 -12.988468686294027 0.20980797455836261 3.1746768393311575e-16 1.4962180211179137 0.5058226259023573 0.13117851627804428 63.09796303456369 1.1174596580715015 27.423369133685224 0.309290825072026 1.0269074715666351e-13 12.988468686294027 1.4962180211179135 EVSFQSTGESEWK ddPTM_PC-9_Lapatinib_30min_R1 1 EVSFQSTGESEWK 13 0 I3L3Q7;I3L3B0;Q07021 I3L3Q7 C1QBP Complement component 1 Q subcomponent-binding protein, mitochondrial 0 160.69 0.0013472000000000002 5204200.0 13751.0 16743.0 13704.0 12897.0 12620.0 13560.0 14516.0 13105.0 15893.0 10575.0 False True 13554.908218375442 16704.232612186865 12577.31001896978 13845.488403130792 11877.716411874626 12980.07040990388 15267.567452666513 13713.906142154612 14102.962979290563 12402.874659698236 1.0928843990031287 1.3468033073385328 1.0140641072378447 1.1163128535129174 0.9576583443570502 1.0465372557606485 1.2309700671471573 1.1057038403134418 1.1370721196688842 1.0 13.598386917632668 -5.2774292255698905 24.99779985888349 1.0815049340325364 1.2198438782714072 0.2735940033503882 0.09338853028318321 948.9966484654473 1483617.7334572936 0.02436469176659772 0.05096939119045894 5.279232323314728e-06 5.2774292255698905 0.13833894423887072 EVSKPVGGAEGVEVPRS(ph)PVLLCK ddPTM_PC-9_AZD4547_30min_R2 2 EVSKPVGGAEGVEVPRSPVLLCK 23 2 Q8TED9;Q8TED9-2;Q8TED9-3 Q8TED9 AFAP1L1 Actin filament-associated protein 1-like 1 1 EVSKPVGGAEGVEVPRS(1)PVLLCK;EVSKPVGGAEGVEVPRS(1)PVLLCK 72.77199999999999 0.00020441 36159000.0 83243.0 68445.0 108092.0 118077.0 113362.0 105004.0 111500.0 121589.0 86318.0 107511.0 True False 109712.54243803803 90568.50773507454 106658.62945394173 90856.17192146473 97623.64307055603 98438.08328065481 121423.28399587864 102800.21388726168 90880.5932583103 103747.0726138016 1.0575001267403745 0.8729741037823374 1.0280639903062943 0.8757468488742498 0.9409773269840583 0.9488275746062783 1.17037792909952 0.9908733933142904 0.8759822418952796 1.0 16.662711103569777 EVSKPVGGAEGVEVPRS(ph)PVLLCK ddPTM_PC-9_Lapatinib_30min_R1 2 EVSKPVGGAEGVEVPRSPVLLCK 23 2 Q8TED9;Q8TED9-2;Q8TED9-3 Q8TED9 AFAP1L1 Actin filament-associated protein 1-like 1 1 EVSKPVGGAEGVEVPRS(1)PVLLCK;EVSKPVGGAEGVEVPRS(1)PVLLCK 72.793 0.00020336 38959000.0 66523.0 76567.0 95965.0 79612.0 104114.0 87423.0 70306.0 69463.0 102261.0 78637.0 True False 65574.36982117603 76389.7138157626 88075.1281356125 85466.9320578468 97990.2192159996 83684.12208296667 73946.10067010007 72690.50456714886 90743.28932393088 92229.30067278411 0.7109928118594782 0.8282586256051315 0.9549582127711235 0.9266787391251161 1.0624629971298858 0.9073485483736403 0.8017636491948462 0.788149796614462 0.9838878606038076 1.0 16.492937538228404 -4.923331024807091 2.8256499951791016 0.9197713029259919 0.7017329992825958 0.4184448877407402 0.0800265927372459 0.35593746763124895 4.860645720968061 0.022599236863308874 0.15570367883271743 1.1930783782109926e-05 4.923331024807091 -0.21803830364339605 EVSPDPSTTGAAS(ph)PASSSAGGSAAR ddPTM_PC-9_Lapatinib_30min_R1 2 EVSPDPSTTGAASPASSSAGGSAAR 25 0 P23769-2;P23769 P23769-2 GATA2 Endothelial transcription factor GATA-2 1 EVSPDPS(0.008)T(0.028)T(0.069)GAAS(0.842)PAS(0.02)S(0.006)S(0.025)AGGS(0.002)AAR;EVSPDPS(0.008)T(0.04)T(0.026)GAAS(0.924)PAS(0.001)SSAGGSAAR 219.21 2.1434999999999998e-100 0.0 10110.1 14175.0 14684.0 9640.9 10462.1 13767.5 13941.4 14233.5 13974.400000000001 9175.7 True False 9965.928120034734 14142.178658409402 13476.738201879167 10349.9239470996 9846.739847279998 13178.696118610009 14663.217476205897 14894.840371946404 12400.455915044235 10761.707519148276 0.9260545412800325 1.314120332042686 1.252286235980679 0.9617362234277422 0.9149793217999765 1.2245915525172182 1.3625363307928295 1.3840592067238453 1.1522758719264705 1.0 13.393619382533728 -6.97744269716372 24.832236521821482 1.2619858553158525 1.088762127550144 0.1640022781793572 0.16000669579227722 357.937592200931 394034.6663486897 0.058167420473361583 0.05129543777660138 1.0533126569381706e-07 6.97744269716372 -0.1732237277657085 EVSS(ph)LK ddPTM_PC-9_Lapatinib_30min_R1 1 EVSSLK 6 0 P35579;P35579-2 P35579 MYH9 Myosin-9 1 EVS(0.041)S(0.959)LK 98.62899999999999 0.034986 15852000.0 77638.0 108900.0 82845.0 82422.0 86651.0 71165.0 85059.0 84727.0 69349.0 74280.0 True False 76530.86788293443 108647.84874079596 76033.80389094807 88483.588831732 81554.35854242071 68121.4388437176 89462.9388231166 88663.72573112049 61538.185342655335 87119.19902812138 0.8784615645769525 1.2471171676604293 0.8727560025707418 1.0156611839735832 0.9361238332333108 0.7819337138502449 1.0269026784123516 1.017728890075086 0.7063676667044574 1.0 16.410703069560775 -5.328383046225382 24.999998611516364 0.9232418278499765 1.0628002437337924 0.15977640232656753 0.13106385907720397 282.91785189824395 105654.38770488367 0.03256667591221378 0.06779295695021194 4.694798463484577e-06 5.328383046225382 0.1395584158838159 EVSS(ph)RPSTPGLSVVSGISATSEDIPNKIEDLR ddPTM_PC-9_Lapatinib_30min_R1 1 EVSSRPSTPGLSVVSGISATSEDIPNKIEDLR 32 2 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 EVS(0.058)S(0.309)RPS(0.309)T(0.309)PGLS(0.012)VVS(0.003)GIS(0.001)ATSEDIPNKIEDLR 54.683 0.00050287 2841200.0 7238.1 4963.5 6313.5 6489.2 6500.9 7099.9 6316.2 5721.2 5954.3 4733.6 True False 7134.883366695026 4952.00732070653 5794.4284008147715 6966.437415336616 6118.529843261153 6796.253827675261 6643.2219305960425 5987.027838267452 5283.664032441314 5551.796452874474 1.2851485869949175 0.8919648554735107 1.0437033219787215 1.2548077859968558 1.102081082258203 1.2241539986856798 1.196589606082636 1.0783946942376885 0.951703485041435 1.0 12.438738959600645 -8.081055158542064 4.271707291739727 0.9795436478049164 1.1353993216222333 0.26741844230830214 0.10887853235646694 0.3382571261197849 11.03975440550458 0.08112611343736294 0.029055567069588183 8.297453771543714e-09 8.081055158542064 0.1558556738173169 EVSSLEGS(ph)PPPCLGQEEAVCTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EVSSLEGSPPPCLGQEEAVCTK 22 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 EVS(0.042)S(0.034)LEGS(0.924)PPPCLGQEEAVCTK;EVS(0.008)S(0.012)LEGS(0.98)PPPCLGQEEAVCTK;EVS(0.092)S(0.024)LEGS(0.884)PPPCLGQEEAVCTK 140.04 8.5602e-06 7276600.0 70865.2 79098.0 79154.0 81839.0 92885.0 90773.0 88066.0 87079.0 82007.0 60618.2 True False 82861.27870850031 86950.32669952906 81041.33155321662 77253.8261556179 74684.85103055167 86012.70408326623 79723.75093737397 84793.26851782718 83206.19723299822 71607.79980659284 1.1571543732987501 1.214257761506082 1.1317388855977004 1.0788465273933083 1.0429708946828378 1.2011638999603385 1.1133389261044424 1.1841345320879468 1.1619711464076785 1.0 16.127829119684545 -5.395864686343739 5.974191316067319 1.1193365076174169 1.1849784593880042 0.18295349151467333 0.060097387183807416 0.40417650382210624 17.776752519025003 0.01582468478890705 0.0334588988693906 4.019160168014254e-06 5.395864686343739 0.06564195177058729 EVSSLEGS(ph)PPPCLGQEEAVCTK ddPTM_PC-9_Lapatinib_30min_R1 2 EVSSLEGSPPPCLGQEEAVCTK 22 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 EVS(0.001)S(0.006)LEGS(0.993)PPPCLGQEEAVCTK;EVS(0.004)S(0.016)LEGS(0.98)PPPCLGQEEAVCTK 190.61 5.0409e-53 6016900.0 88833.0 103202.0 98653.0 80598.0 101903.0 92429.0 78437.0 84356.0 104977.0 81053.0 True False 87566.22513002287 102963.04210971193 90542.1311515924 86525.44578704634 95909.26588900638 88476.02713252266 82498.08406481134 88275.48771671818 93153.38480318294 95062.90305366617 0.9211398170807893 1.0831043319977915 0.9524444156778838 0.9101914943434858 1.0089031873438832 0.9307103432616086 0.8678262646601317 0.9286007988508802 0.9799131081721201 1.0 16.536594839228584 -5.495244421592607 24.861061740819057 0.9414273814426142 1.0060351641255638 0.13619589977679347 0.05411464213855783 1054.06118048579 948278.4765407868 0.01377887574917072 0.028563859565293722 3.197095273198465e-06 5.495244421592607 0.06460778268294964 EVSSRPS(ph)TPGLSVVSGISATSEDIPNKIEDLR ddPTM_PC-9_AZD4547_30min_R2 1 EVSSRPSTPGLSVVSGISATSEDIPNKIEDLR 32 2 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 EVS(0.029)S(0.029)RPS(0.465)T(0.465)PGLS(0.008)VVS(0.001)GIS(0.001)ATSEDIPNKIEDLR 54.363 0.0005191 3777500.0 4462.2 5111.0 6708.1 7360.5 6185.8 6907.0 3698.0 5407.0 3474.8 5078.5 True False 5881.086780474184 6763.030798947567 6619.146211005325 5663.650443591392 5327.008444680271 6475.104198120876 4027.1148360247507 4571.472390499336 3658.4708340552033 4900.703260775093 1.2000495576922634 1.3800123041683467 1.3506523163694761 1.155681162930814 1.0869885731130258 1.3212602056417462 0.8217422320297401 0.9328196683706806 0.7465195583942744 1.0 12.258773078386113 -7.263763456362378 24.999416944549477 0.869671987785021 1.2480575831256333 0.755483464699019 0.10417033167178205 106.16414718839353 1141966.2813069797 0.043708387131460795 0.031059896826392756 5.447993034465345e-08 7.263763456362378 0.37838559534061234 EVSSRPS(ph)TPGLSVVSGISATSEDIPNKIEDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVSSRPSTPGLSVVSGISATSEDIPNKIEDLR 32 2 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 EVS(0.02)S(0.071)RPS(0.448)T(0.448)PGLS(0.011)VVSGISAT(0.001)SEDIPNKIEDLR 71.296 7.5708000000000004e-06 4940100.0 10431.0 11297.0 9067.0 12213.0 16430.0 13882.0 13457.0 10028.0 9834.2 9814.3 True False 12196.762278359025 12418.491500727978 9283.191666788985 11528.745205080233 13210.659443741864 13154.003482135671 12182.255539756998 9764.77562554427 9978.006570521447 11593.55490004395 1.0520295443042056 1.0711547586392938 0.8007200334000915 0.9944098513766928 1.1394830625843488 1.134596212770408 1.0507782681661184 0.8422589714486324 0.8606511683904323 1.0 13.501035383365272 -7.754385796467784 24.99833403425018 0.8885912951896184 1.0334569029849294 0.281805715606928 0.0972456593156666 210.38649472737993 745630.2521669738 0.05115299292535478 0.028721113377691173 1.760411526654739e-08 7.754385796467784 0.144865607795311 EVSSRPS(ph)TPGLSVVSGISATSEDIPNKIEDLR ddPTM_PC-9_Lapatinib_30min_R1 1 EVSSRPSTPGLSVVSGISATSEDIPNKIEDLR 32 2 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 EVS(0.057)S(0.154)RPS(0.374)T(0.374)PGLS(0.039)VVS(0.001)GIS(0.001)AT(0.001)SEDIPNKIEDLR 55.818999999999996 0.00044539 4601100.0 7334.6 6113.8 7296.8 5445.9 6627.3 7515.8 5500.2 8950.8 7923.5 7676.8 True False 7230.007258999097 6099.643871730756 6696.88527046254 5846.409652989836 6237.495243773113 7194.366754185514 5784.973443314708 9366.686844501906 7031.071991846018 9003.724651306991 0.8030018174700156 0.6774578419438142 0.7437905455594327 0.6493323462686261 0.6927683248140725 0.7990433995714397 0.6425089246232063 1.0403124492642306 0.7809070428231476 1.0 13.136306222144066 -7.755812940024181 24.999032048920554 0.9329573184093067 0.7148500722176698 0.615696409254781 0.0813926347295471 83.67782795065305 371796.7855050596 0.036588373146910436 0.020363917754500385 1.754636098617272e-08 7.755812940024181 -0.2181072461916369 EVSTYIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVSTYIK 7 0 Q5VTE0;P68104;A0A087WVQ9;A0A087WV01 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 0 114.78 0.039222 12944000.0 76698.0 79946.0 72594.0 82061.0 87120.0 88694.0 65790.0 66244.0 71869.0 59175.0 False True 89681.45654544934 87882.51053529237 74324.91627427828 77463.38821535144 70049.4613961528 84042.73050313657 59557.89492164774 64505.16519131976 72919.94816220997 69902.95907095775 1.2829422064152485 1.2572073014260208 1.063258512401912 1.108156067280631 1.002095795759466 1.2022771513552908 0.8520082084249274 0.9227816110880407 1.0431596763763564 1.0 16.093065907348137 -4.001641996725704 0.40710441057245467 0.9653017929619473 1.8424753632744113 0.5809640838501975 0.08653416631926301 7.3477116455112075 0.5881918116880092 0.06688421209643658 3.559587537113381 9.962263011823858e-05 4.001641996725704 0.877173570312464 EVSTYIK ddPTM_PC-9_Lapatinib_30min_R1 2 EVSTYIK 7 0 Q5VTE0;P68104;A0A087WVQ9;A0A087WV01 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 0 ; 129.4 0.020390000000000002 110870000.0 232730.0 231880.0 233940.0 230700.0 241120.0 210506.0 222700.0 204660.0 218638.0 189863.0 False True 229411.22752254497 231343.09610666498 214706.356234515 247666.44759263968 226937.79566015943 201503.14909345316 234230.31632053095 214169.25074806265 194012.686079792 222680.56657345482 1.030225632405466 1.0389011473542873 0.9641899135535502 1.1122050361361142 1.0191180988633792 0.9048977743955221 1.0518668958176296 0.9617779137337313 0.8712600702665886 1.0 17.764616133454084 -6.549205570502811 20.557534389149012 0.9615034513522311 1.0356861837715337 0.307700923444749 0.05657091763205255 40.275586803730995 31447.887182158927 0.01852436115081624 0.018526543689316676 2.823543152541599e-07 6.549205570502811 0.07418273241930251 EVTGAVR ddPTM_PC-9_AZD4547_30min_R2 3 EVTGAVR 7 0 A0A2C9F2M8;Q8NG84 A0A2C9F2M8 OR2AK2 Olfactory receptor 2AK2 0 ;; 109.7 0.044108 53177500.0 314499.0 302731.0 300734.0 386596.0 286806.0 213816.0 183030.0 290545.0 146741.0 164081.0 False True 414503.1400144215 400582.87552263663 296746.0706638952 297472.26504865923 246987.9375319232 200446.05171933043 199319.31542390768 245647.9463098998 154497.42968231096 158336.57413236928 2.6178609855982935 2.5299453251258903 1.8741473490250944 1.8787337460009246 1.5598918878050338 1.2659491517844617 1.2588330682036664 1.551428958571115 0.9757532681814324 1.0 17.272635016234076 -4.260123698430594 0.3496436513711394 1.0516535182338411 4.75250901526282 0.9196464595946872 0.155495411367642 2.407579543437663 0.17813193282561027 0.14376847930716694 4.035546308981694 5.493843725283839e-05 4.260123698430594 3.700855497028979 up EVTGAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EVTGAVR 7 0 A0A2C9F2M8;Q8NG84 A0A2C9F2M8 OR2AK2 Olfactory receptor 2AK2 0 ;; 127.66 0.020733 26353500.0 78363.0 152053.0 67607.0 165981.0 155575.0 167525.0 171264.0 130522.0 93358.0 106033.0 False True 91628.30816019999 167147.81695673132 69219.00728097527 156681.62268766234 125091.19555448214 158739.69408909214 155040.63407601553 127095.93579949038 94723.18413401624 125255.94354323373 0.7315286250554113 1.334450184386165 0.5526205409732388 1.2508917202286822 0.9986847092114657 1.2673226483204851 1.2377906364379525 1.0146898598518126 0.7562370411693979 1.0 16.934519537074102 -4.707793131379008 23.89047037067068 1.0487519027559895 0.731516504318225 0.14044564419301253 0.23318400750783363 27503.406843594723 12246024.813601557 0.05621006086798681 81.5644194318617 1.9597779573471216e-05 4.707793131379008 -0.3172353984377645 EVTWEVLEGEVEK ddPTM_PC-9_Lapatinib_30min_R1 2 EVTWEVLEGEVEK 13 0 P05455 P05455 SSB Lupus La protein 0 ; 197.07 5.5966e-47 0.0 19863.4 17820.6 17437.0 15142.9 15774.3 13847.7 17455.5 17774.7 15693.5 17141.0 False True 19580.14427349856 17779.337495594395 16003.39716876648 16256.559381233552 14846.486687467022 13255.466151565348 18359.26037958255 18600.577451732584 13925.932770118705 20103.79901105317 0.973952448625919 0.8843770018701056 0.79603845820224 0.8086312130506087 0.7384915994884524 0.6593513068986327 0.9132234345104892 0.9252269902572093 0.6927015517048374 1.0 14.295180532521805 -10.557550776024213 21.285064066226518 0.999999999981466 0.8206271181795527 0.22855415405544133 0.09846700000302729 0.0 0.0 0.09911039860940717 0.024037802474332678 2.7698051853666863e-11 10.557550776024213 -0.17937288180191335 EVVEEAENGR ddPTM_PC-9_AZD4547_30min_R2 1 EVVEEAENGR 10 0 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 0 128.35 0.0013020999999999998 41679000.0 26920.0 34692.0 46672.0 43104.0 41187.0 45653.0 41541.0 53595.0 42750.0 30057.0 False True 35480.000029215444 45905.51056096438 46053.09878505692 33167.03875016144 35468.895989370205 42798.310693037805 45238.068524419716 45313.124240579265 45009.67772414524 29004.713578638766 1.2232494533352525 1.5826913938144391 1.5877798158632346 1.1435051292693377 1.2228666176345953 1.4755639829712945 1.5596798914000103 1.5622675989447188 1.5518056264238969 1.0 14.823999752339299 -6.897869840605486 19.277532045368112 1.4732538258723222 1.3646161568814863 0.01129966991503717 0.20781503425537187 8.163887469009463 1511.7213201472114 0.07366941033416104 0.06497048623556169 1.2651154496580102e-07 6.897869840605486 -0.10863766899083593 EVVEEAENGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EVVEEAENGR 10 0 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 0 ; 151.83 0.00077014 75990000.0 123592.0 196030.0 170121.0 160959.0 179044.0 129618.0 201795.0 134070.0 149788.0 119703.0 False True 144513.68454673057 215490.56288286357 174177.32982748488 151940.98906611901 143961.61347810793 122820.60390055194 182679.5167307173 130550.80455890742 151978.36612894444 141404.20633157308 1.0219899980051952 1.5239331875147217 1.2317690848535539 1.0745153415722206 1.018085792586241 0.8685781497373197 1.291895916464885 0.923245552206446 1.07477966937261 1.0 17.109465510874372 -5.743922416818438 3.6162133734823505 1.032677045473308 1.2944891654834867 0.3077817536004661 0.1540211491646322 0.2412798489493435 6.6830581512239675 0.041725618736006984 0.07192188802307362 1.8033398641051527e-06 5.743922416818438 0.2618121200101786 EVVEEAENGR ddPTM_PC-9_Lapatinib_30min_R1 3 EVVEEAENGR 10 0 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 0 ;; 128.91 0.0012165999999999998 61841000.0 79476.0 78337.0 87120.0 70103.0 81687.0 85607.0 77702.0 82215.0 82532.0 62803.0 False True 78342.65766588647 78155.61548951096 79957.32989292534 75258.60847675255 76882.33126282111 81945.78816966378 81725.02936119409 86035.00904061353 73236.37705951098 73658.4148702627 1.0635941297932394 1.061054811282178 1.085515212807079 1.0217245186352208 1.0437684736799837 1.112510883026711 1.1095138214030185 1.1680268872490698 0.9942703381345489 1.0 16.168562730311162 -6.749148873130672 24.979679689403092 1.0894066586820739 1.0552925529770225 0.014688190720694716 0.05141873444920603 560.3868561326053 1138948.2998668565 0.01651076210651979 0.016396520520987057 1.7817678851006823e-07 6.749148873130672 -0.034114105705051356 EVVESCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVVESCR 7 0 O60701;O60701-2;E7ER83;E7ETF4;E7EV97;E7ER95 O60701 UGDH UDP-glucose 6-dehydrogenase 0 85.265 0.034953 0.0 14064.0 16500.0 19223.0 20512.0 24436.0 17835.0 20733.0 19792.0 19438.0 18316.0 False True 16444.757423338262 18138.010955298898 19681.34922363348 19362.77914080126 19647.941215293744 16899.701203276887 18769.02014607877 19272.48097135743 19722.243976916874 21636.545810623764 0.760045414239075 0.8383043723362233 0.9096345320503856 0.8949108286635078 0.9080904774387049 0.7810720505571163 0.8674684171104146 0.8907374189966332 0.9115246097754223 1.0 14.401182576512344 -14.522878745162716 0.12640771957716523 1.4575686468278422 0.8035446741433239 0.4993867620431083 0.046571039966054564 144.25363177565697 1.1576637131400693 16.695024483975622 0.4175240440056291 3.0000000008125013e-15 14.522878745162716 -0.6540239726845183 EVVETPLLHPER ddPTM_PC-9_Lapatinib_30min_R1 2 EVVETPLLHPER 12 0 P35998;P35998-2 P35998 PSMC2 26S protease regulatory subunit 7 0 ; 101.53 0.0022586 5778800.0 44853.0 61471.0 66485.0 60765.0 63824.0 62940.0 57066.0 62200.0 55017.0 55320.0 False True 44213.38799496717 61328.667676266974 61018.85993952171 65233.86080609773 60069.9978028119 60248.202920306074 60020.59825391755 65090.039072263724 48820.40610530605 64881.98829073344 0.6814431733634433 0.9452340979665391 0.9404591558769559 1.0054232696104743 0.9258347252497995 0.9285813290791342 0.9250733498635676 1.003206603049802 0.7524492912662275 1.0 15.98553041077585 -4.760421756428421 24.999944742491774 0.9377301367736282 0.6814428709309709 0.5513949948790136 0.0689385321281137 18.12633671939912 445092.44516336697 0.016048274572086393 0.09527109801224078 1.7361140173068907e-05 4.760421756428421 -0.25628726584265726 EVVKGPCAPAAS(ph)SPTQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVVKGPCAPAASSPTQK 17 1 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 EVVKGPCAPAAS(0.474)S(0.474)PT(0.053)QK 65.51100000000001 0.010091 5778800.0 26287.0 13714.0 15120.0 20156.0 26926.0 28481.0 26123.0 28725.0 22016.0 26041.0 True False 30736.86990808396 15075.435287331453 15480.518142919324 19026.724666633687 21650.043589908302 26987.40622206498 23648.44032585809 27970.9991866533 22337.94234982004 30762.027159557416 0.9991821978654734 0.4900663798629956 0.5032346555909499 0.6185133563514945 0.7037911863744609 0.8772960924221893 0.7687542892800153 0.9092703494985057 0.726153131390104 1.0 14.90886295686338 -6.6019852483549215 3.650883573902216 0.8450518266098163 0.6323791457541177 0.29515213142467345 0.14877837989601564 0.2917995585014979 7.708283103144784 0.050287721975787486 0.05078461564606069 2.500430292164846e-07 6.6019852483549215 -0.21267268085569857 EVVKGPGAPAASS(ph)PTQK ddPTM_PC-9_AZD4547_30min_R2 1 EVVKGPGAPAASSPTQK 17 1 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 EVVKGPGAPAAS(0.13)S(0.785)PT(0.086)QK 68.458 0.00821 10525000.0 32784.0 20464.0 32712.0 55055.0 44584.0 35229.0 29363.0 31622.0 25960.0 40142.0 True False 43208.63005043826 27078.587804668943 32278.217506358917 42362.920341270845 38394.281175858436 33026.125060894796 31976.25011633173 26735.5465012706 27332.192601609604 38736.640798273875 1.1154459746639585 0.699043263603683 0.8332735322727636 1.0936136812141584 0.9911618659914699 0.8525810287185888 0.8254781379431488 0.6901875317609355 0.7055901605909912 1.0 15.241411229881974 -7.13467893644362 2.6481656736588954 0.7764048421700214 0.9333839173696277 0.17346617026069167 0.13874999332367627 0.48205496901472994 6.566286212817458 0.06116530822464597 0.04492622997545355 7.333664931492301e-08 7.13467893644362 0.1569790751996063 EVVKGPGAPAASS(ph)PTQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EVVKGPGAPAASSPTQK 17 1 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 EVVKGPGAPAAS(0.2)S(0.618)PT(0.182)QK;EVVKGPGAPAAS(0.113)S(0.844)PT(0.042)QK;EVVKGPGAPAAS(0.248)S(0.658)PT(0.094)QK 85.397 0.0015297000000000002 38192000.0 113911.0 56506.0 89959.0 138366.0 137197.0 172800.0 157460.0 181159.0 167383.0 125950.0 True False 133193.8824551964 62115.5422448557 92103.96373140738 130613.80160862452 110314.23272690496 163738.06380298553 142544.24888832148 176403.76820382662 169830.6597174753 148783.73798034835 0.8952180141675761 0.41748878666470957 0.6190459050274207 0.8778768659910685 0.7414401212414456 1.1005104860627468 0.9580633664893472 1.1856387707312903 1.1414598263414168 1.0 17.18285732334776 -6.529044495053398 1.068305104904279 1.1066836859014506 0.6323001811003434 0.6184529660112259 0.1422676042559625 0.3086224568685288 0.7518136968977411 0.0679736582136408 0.07793193115912643 2.957709422911691e-07 6.529044495053398 -0.47438350480110725 EVVKGPGAPAASS(ph)PTQK ddPTM_PC-9_Lapatinib_30min_R1 2 EVVKGPGAPAASSPTQK 17 1 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 EVVKGPGAPAAS(0.059)S(0.642)PT(0.299)QK;EVVKGPGAPAAS(0.36)S(0.618)PT(0.022)QK 107.06 0.0013168 10066000.0 138482.0 89309.0 85505.0 80595.0 83323.0 101113.0 85574.0 80639.0 114223.0 75310.0 True False 136507.22128551142 89102.21049762842 78475.10895884495 86522.22515703861 78422.1049593208 96788.63269591531 90004.6030032022 84385.7823271429 101358.00291848653 88327.23315573257 1.5454714973900652 1.0087739343145672 0.8884588156461664 0.9795645359397652 0.8878587289273772 1.095796044298865 1.0189904040638542 0.9553767203186317 1.1475283363600781 1.0 16.43057069943071 -4.762008493803023 6.600990150349979 0.991957006158888 1.5600522990890968 0.8209188557162663 0.07669775417531698 0.045804012507552824 9.818011584283292 0.018991664338863908 0.11715936671918695 1.7297825283092147e-05 4.762008493803023 0.5680952929302088 EVVKGPGAPAASSPT(ph)QK ddPTM_PC-9_AZD4547_30min_R2 1 EVVKGPGAPAASSPTQK 17 1 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 EVVKGPGAPAAS(0.045)S(0.139)PT(0.816)QK 72.86399999999999 0.0082461 10869000.0 35663.0 24184.0 36603.0 56589.0 54105.0 39665.0 28516.0 38917.0 29752.0 44122.0 True False 47003.09216351817 32001.005056104073 36117.620304024655 43543.28034133461 46593.45467028126 37184.741279638714 31053.868757188146 32903.27187369386 31324.629980088186 42577.30220969159 1.1039471672495766 0.7515977620775582 0.848283438113264 1.0226876312380155 1.0943261374525393 0.8733465802155638 0.7293526631689586 0.7727890252803361 0.7357119487236551 1.0 15.37779691994552 -7.000428508214608 24.998376351896074 0.7920749283118323 0.9526384036336158 0.25663280661068066 0.12243349134970394 21.47525781805844 1252908.8666293153 0.04427890959115674 0.03861991117227386 9.990138099781485e-08 7.000428508214608 0.1605634753217835 EVVKGPGAPAASSPT(ph)QK ddPTM_PC-9_Lapatinib_30min_R1 1 EVVKGPGAPAASSPTQK 17 1 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 EVVKGPGAPAAS(0.072)S(0.191)PT(0.737)QK 78.244 0.005160499999999999 11396000.0 118830.0 72498.0 64972.0 64563.0 68446.0 78098.0 55017.0 63760.0 85680.0 69675.0 True False 117135.46240924705 72330.13533526385 59630.25295917278 69311.17839585434 64420.140850013566 74757.93059532985 57865.511059751516 66722.52236732372 76029.81614960147 81718.23091389843 1.4334067331029916 0.8851162650776637 0.7297056274015719 0.8481727714943236 0.7883203066141897 0.9148256118527305 0.7081101782626806 0.8164949439204725 0.9303898934095808 1.0 16.31837035161653 -4.764635607626514 4.6095319466688345 0.8300550434916745 1.4794837334619508 0.808618214631307 0.08567569214639112 0.07295052786788665 3.556728074961201 0.020112647233234717 0.15619288168267878 1.7193503935197326e-05 4.764635607626514 0.6494286899702764 EVVKPVPIT(ph)SPAVSK ddPTM_PC-9_AZD4547_30min_R2 1 EVVKPVPITSPAVSK 15 1 Q96HC4;A0A0D9SFR4 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 1 EVVKPVPIT(0.662)S(0.337)PAVS(0.001)K 149.12 9.509899999999999e-05 134750000.0 117790.0 132480.0 153250.0 200280.0 192710.0 166740.0 155400.0 192750.0 174370.0 163790.0 True False 155244.76981579838 175301.56921239922 151217.80486822882 154108.54029515435 165955.54291673444 156313.72144124398 169230.29895031033 162964.91645436452 183586.84221658972 158055.76195379606 0.9822151872019736 1.1091121705746139 0.956737059117363 0.9750263982163739 1.0499809742162245 0.9889783169495502 1.0706999660017513 1.0310596364212494 1.1615321070690046 1.0 17.270074104368526 -7.276124968176742 23.798725347273496 1.0684112418547391 1.0125912244560369 0.1888910559232232 0.05610466888774368 757.4607782583835 1227495.4901883248 0.02269245184727362 0.015384711834177198 5.2951105523533203e-08 7.276124968176742 -0.05582001739870224 EVVKPVPIT(ph)SPAVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVVKPVPITSPAVSK 15 1 Q96HC4;A0A0D9SFR4 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 1 EVVKPVPIT(0.496)S(0.496)PAVS(0.008)K 75.319 0.010879999999999999 98858000.0 65601.0 66395.0 71428.0 68576.0 69363.0 74934.0 74440.0 57145.0 57355.0 50196.0 True False 76705.95362118969 72986.25681073156 73131.11441219831 64733.90904639165 55771.81807646175 71004.3291262322 67388.50430107079 55645.00430013238 58193.708370000415 59296.137448682595 1.2936079299865746 1.2308770849348658 1.2333200366632497 1.0917053257038054 0.9405640987109668 1.1974528558067103 1.1364737603590398 0.9384254471598582 0.9814080794109689 1.0 15.855650510203988 -2.803644924937486 0.27667659062107425 0.9789641997463194 2.2700377468981645 0.6005375824526473 0.07961609087060981 19.33581038356602 0.5074448592673971 0.09997433583321153 10.416371848101303 0.0015716472431168663 2.803644924937486 1.291073547151845 EVVKPVPIT(ph)SPAVSK ddPTM_PC-9_Lapatinib_30min_R1 1 EVVKPVPITSPAVSK 15 1 Q96HC4;A0A0D9SFR4 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 1 EVVKPVPIT(0.497)S(0.497)PAVS(0.007)K 112.58 0.00021869999999999998 85059000.0 164700.0 157030.0 169410.0 136500.0 129840.0 125240.0 111950.0 104530.0 128150.0 89910.0 True False 162351.34779771918 156666.40668289477 155481.76374151098 146538.6653506513 122203.0664752616 119883.77714869943 117746.22322444317 109386.84540552633 113716.39752067499 105450.82370245548 1.5395929789587668 1.4856821519474457 1.4744480724041087 1.3896398359497981 1.1588630812413088 1.1368690441619365 1.1165984208590054 1.0373256610510402 1.0783832077172009 1.0 16.686210838860084 -6.2284341899011855 1.1029996233183248 1.058357448849321 1.529349151349379 0.9714421903309078 0.03314487751557662 0.07510371370279269 0.1896183474919375 0.014071402009541078 0.02191320138851198 5.909705105327753e-07 6.2284341899011855 0.47099170250005806 EVVKPVPITS(ph)PAVSK ddPTM_PC-9_AZD4547_30min_R2 1 EVVKPVPITSPAVSK 15 1 Q96HC4;A0A0D9SFR4 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 1 EVVKPVPIT(0.23)S(0.77)PAVS(0.001)K 122.1 2.6169e-05 108240000.0 82496.0 85615.0 117850.0 138560.0 123990.0 115720.0 115440.0 131860.0 120150.0 119500.0 True False 108728.0119766029 113288.37445742433 116287.23199817799 106617.13273066012 106776.1287231896 108484.01010663758 125713.9363630875 111484.06684136188 126500.88370891343 115316.34137296937 0.94286733937337 0.9824138808827974 1.0084193672262671 0.9245622212885399 0.9259410023930778 0.9407514044845224 1.0901658417733617 0.9667672899956763 1.0969900900668512 1.0 16.815237444904604 -7.242437092691043 24.88867666362789 1.0357114163907484 0.9552819104426079 0.4795454012893008 0.042986671997336474 698.989453859487 915518.2217071835 0.016098126538058918 0.012449010440506798 5.7221983436753996e-08 7.242437092691043 -0.08042950594814047 EVVKPVPITS(ph)PAVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVVKPVPITSPAVSK 15 1 Q96HC4;A0A0D9SFR4 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 1 EVVKPVPIT(0.091)S(0.889)PAVS(0.02)K 139.78 3.0446e-05 75645000.0 155260.0 149280.0 163100.0 199870.0 216130.0 179130.0 189230.0 183060.0 167740.0 137320.0 True False 181542.4514752205 164099.53184284977 166988.92256019468 188671.931887283 173780.8780021864 169736.1074596573 171304.76449344005 178254.86896810285 170192.88016709764 162215.02897547834 1.1191469287513665 1.011617313631626 1.0294294160958293 1.1630977294699623 1.0712994911738816 1.0463648684815505 1.0560351009112465 1.098880110517067 1.0491807155108006 1.0 17.30754796368342 -8.539192830909858 20.090996333833274 0.9999999972507947 1.072297435816945 0.2264743740111449 0.04195701222161063 300.58556443563305 370177.7720093547 0.041039025610348584 0.010596230850007033 2.8893966777079666e-09 8.539192830909858 0.07229743856615034 EVVKPVPITS(ph)PAVSK ddPTM_PC-9_Lapatinib_30min_R1 1 EVVKPVPITSPAVSK 15 1 Q96HC4;A0A0D9SFR4 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 1 EVVKPVPIT(0.075)S(0.924)PAVSK 146.67 5.5833999999999994e-05 103180000.0 120380.0 98851.0 107880.0 83892.0 89082.0 85423.0 74960.0 73632.0 75261.0 58814.0 True False 118663.35912501162 98622.11658288726 99010.52282884246 90061.69753550811 83842.37190195051 81769.65742073896 78841.06201790314 77053.21152683176 66784.31364653539 68979.92153527109 1.7202594100420394 1.4297220754659659 1.4353527899885477 1.305621919118267 1.2154605287435691 1.1854124446767915 1.142956678742956 1.1170382600019717 0.9681703336294311 1.0 16.073888867282115 -1.5228787452803407 0.2372607311180645 0.9650909643157117 5.240855774195832 0.9498903932834776 0.04838942779051658 9.700341958500033 0.12891136819074664 0.06513381678309757 16.27001661149671 0.02999999999999978 1.5228787452803407 4.27576480988012 EVVQGSGAPAALS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 EVVQGSGAPAALSPK 15 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 EVVQGSGAPAALS(1)PK;EVVQGSGAPAALS(1)PK 188.96 2.3115999999999999e-07 46717000.0 238010.0 233583.0 232356.0 229610.0 226890.0 243340.0 211266.0 217899.0 215380.0 243860.0 True False 313692.2290844559 309084.1367854765 229274.80762128645 176676.9619391373 195390.23990648068 228123.91133208867 230068.26472352745 184227.71637089216 226764.54709301534 235322.5356252076 1.333030974917191 1.3134489476934212 0.974300259905608 0.7507864109560946 0.8303082379567501 0.9694095413599316 0.9776720453579997 0.7828732419588879 0.9636329410209044 1.0 17.844279961076055 -5.306552300122437 3.7408665516161776 0.8895535875858562 1.3331673556002883 0.80825696252928 0.08186584477907283 0.08611934644637702 2.5198898733874078 0.022171326953978977 0.05471165084797309 4.93682462721104e-06 5.306552300122437 0.4436137680144321 EVVQGSGAPAALS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EVVQGSGAPAALSPK 15 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 EVVQGSGAPAALS(1)PK;EVVQGSGAPAALS(1)PK 193.19 1.5613e-09 30815000.0 216745.0 239689.0 167562.0 225783.0 224405.0 181327.0 259265.0 240035.0 189285.0 176021.0 True False 253435.64759111582 263483.73987058416 171557.31356242372 213133.1105083623 180434.45115477126 171817.89291206 234705.54228394903 233734.33558810467 192052.93503296204 207932.2139185309 1.2188378261119917 1.267161710565053 0.8250636605525727 1.0250124619548808 0.8677561199125526 0.8263168542964645 1.1287598869884976 1.124089101843946 0.9236324252682152 1.0 17.665753759618497 -5.244991788943245 24.773160281075512 0.9690652126248482 1.2429998320702798 0.5328594500866695 0.1040339765448473 595.8859133925458 897512.1306944953 0.028010864402410112 0.07362958336617847 5.688636860526937e-06 5.244991788943245 0.2739346194454315 EVVQGSGAPAALS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 EVVQGSGAPAALSPK 15 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 EVVQGSGAPAALS(1)PK;EVVQGSGAPAALS(1)PK 198.98 6.3907e-10 46972000.0 195586.0 224604.0 180900.0 207947.0 211588.0 197747.0 201641.0 169021.0 168592.0 154817.0 True False 192796.90777392 224083.94323762835 166027.1002941942 223240.11607085634 199142.80983801346 189289.82178077183 212080.98434300968 176874.33270149687 149603.39360753502 181576.9121693143 1.0617919727269258 1.2340993167054062 0.9143623950350008 1.229452100510953 1.096740810595565 1.0424773696132992 1.1679953239057803 0.9741014459843196 0.8239119820918362 1.0 17.470221247460046 -7.934594000940983 5.267892730226902 0.907306861687111 1.1053747644765692 0.4119558962927238 0.09698966231424333 0.1711503259320227 9.044465769538572 0.05219201352145549 0.023998872419118005 1.1625348987114009e-08 7.934594000940983 0.19806790278945818 EVVQGSSAS(ph)AASSPTWK ddPTM_PC-9_AZD4547_30min_R2 2 EVVQGSSASAASSPTWK 17 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 EVVQGSSAS(0.886)AAS(0.081)S(0.033)PTWK;EVVQGSSAS(0.968)AAS(0.022)S(0.01)PTWK 230.48 1.8180999999999997e-29 22159000.0 157919.0 137445.0 173321.0 248640.0 206593.0 201439.0 160734.0 198958.0 185890.0 173634.0 True False 208133.9570807458 181871.40836653247 171022.65029407048 191319.88944970618 177911.1280047579 188842.98748592357 175039.01461698304 168213.6127000121 195715.7658980436 167555.12651007672 1.242181969694784 1.0854422192542987 1.0206948235856288 1.1418325027387346 1.0618065332310698 1.1270498934842594 1.044665229066902 1.0039299674301267 1.168067906810797 1.0 17.35427630229534 -4.765093706345626 5.23862564894152 1.0731026490777011 1.251201841579014 0.46060688497190116 0.05520164623555112 0.13711428252335586 10.828500298353246 0.012988153325405713 0.08901428106935415 1.7175377594888497e-05 4.765093706345626 0.1780991925013129 EVVQGSSAS(ph)AASSPTWK ddPTM_PC-9_Lapatinib_30min_R1 2 EVVQGSSASAASSPTWK 17 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 EVVQGSSAS(0.979)AAS(0.021)SPTWK;EVVQGSS(0.001)AS(0.718)AAS(0.167)S(0.105)PT(0.008)WK 185.14 3.3221e-08 7238200.0 90341.0 90255.0 102093.0 95761.0 125373.0 147612.0 146752.0 130937.0 148560.0 127845.0 True False 89052.72077348962 90046.02009275062 93699.30763037669 102803.58338933163 117998.80663280183 141298.97886037847 154350.10049694922 137020.81102901947 131827.6083938468 149942.8379072455 0.593911133178482 0.6005356531163764 0.6249001882193199 0.6856184985169204 0.7869586055573777 0.9423523046014768 1.0293929516822273 0.9138203127366472 0.8791857632799723 1.0 17.19405308725721 -6.413432173462517 1.6062826058783335 0.9561478872053857 0.6065626268412779 0.931566056588794 0.04201584421676929 0.09584347977070913 0.49605871523729556 0.017206109380979526 0.020600671081765064 3.8598268826443646e-07 6.413432173462517 -0.34958526036410775 EVVQGSSASAAS(ph)SPTWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVVQGSSASAASSPTWK 17 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 EVVQGSSAS(0.335)AAS(0.649)S(0.016)PTWK 154.31 2.6082e-05 7130800.0 20167.0 24661.0 29410.0 28188.0 46638.0 44230.0 55046.0 49578.0 41676.0 45572.0 True False 23580.874783593747 27109.181101128826 30111.245938046104 26608.717746729028 37499.61869368427 41910.500937535006 49831.64438147168 48276.63003223312 42285.4326567542 53833.84285224649 0.4380306798516004 0.5035713533498484 0.5593367358278708 0.4942749084392857 0.6965807511941238 0.778515868773542 0.9256564596036859 0.8967710175313731 0.7854804787540748 1.0 15.716225793314681 -6.598254899095668 1.3581332707708085 0.8967189807265626 0.49015290224574426 0.9021775122798857 0.05949398019373068 0.12067910444463734 0.4632448710434463 0.025631540742938514 0.026752459844377453 2.5220001084030674e-07 6.598254899095668 -0.4065660784808184 EVVQGSSASAAS(ph)SPTWK ddPTM_PC-9_Lapatinib_30min_R1 1 EVVQGSSASAASSPTWK 17 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 EVVQGSSAS(0.147)AAS(0.754)S(0.099)PTWK 248.75 1.5699999999999998e-47 8580700.0 34103.0 33489.0 36973.0 38715.0 53089.0 66574.0 53238.0 50694.0 54825.0 49551.0 True False 33616.68496627573 33411.45827805804 33933.22265990728 41562.230249454034 49966.409396989846 63726.78521157391 55994.40314446542 53049.42830754565 48650.0311671557 58115.82432744274 0.5784428829034379 0.5749115437098067 0.5838895525032372 0.7151620187864741 0.8597728755504432 1.0965479015236412 0.9634966688070263 0.9128224355667498 0.8371219324541661 1.0 15.826643427349723 -6.163841956136961 2.093393628554628 0.9571642735050244 0.5786627100861104 0.871533823448565 0.06456694002584418 0.1137944091802569 0.9800978048165875 0.022940724084990375 0.03186596143366363 6.857377274865202e-07 6.163841956136961 -0.37850156341891406 EVVQNFAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EVVQNFAK 8 0 Q14019;H3BT58 Q14019 COTL1 Coactosin-like protein 0 91.853 0.038764 3913100.0 29183.0 26123.0 34730.0 32711.0 47152.0 30776.0 32592.0 40565.0 38017.0 23385.0 False True 34123.105509476685 28716.318799107452 35558.094914258465 30878.308720492856 37912.90408346418 29162.052381948393 29504.6498143539 39500.21173217023 38572.9267039021 27624.515384441853 1.2352472083074024 1.039522988891255 1.2871934374017946 1.1177864404413604 1.3724368936736806 1.055658424269498 1.0680603588423832 1.4298970020815924 1.3963295343680997 1.0 14.7536615351451 -7.756745425490861 24.999239418564013 1.3098349439795967 1.1692429116411476 0.0858486455438674 0.14834589060023373 210.86964895582292 1123076.7558908719 0.06949271673094125 0.0384187664413651 1.7508727135168112e-08 7.756745425490861 -0.14059203233844908 EVVYWS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 EVVYWSPK 8 0 E6ZCI6;C0MHM2;Q86VZ5 E6ZCI6 SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 1 EVVY(0.001)WS(0.999)PK;EVVYWS(1)PK 94.69200000000001 0.012836000000000002 1782400.0 41632.0 45965.0 43923.0 52917.0 48177.0 42826.0 47231.0 45243.0 36779.0 37060.0 True False 54870.11000060539 60822.28735543433 43340.55232122163 40717.80320950012 41488.45514555293 40148.08344993841 51434.46750142918 38251.73393071231 38723.06285418336 35762.54068018607 1.5342900408361002 1.7007261284747701 1.2118980222575206 1.13856013680984 1.1601092751371338 1.1226295080366622 1.4382218523396466 1.0696033671876493 1.0827827698393233 1.0 15.126161613176393 -5.315856509035506 5.754436262493952 1.1619641425430016 1.6172136380962199 0.7190144080839831 0.11618464184521538 0.09797821961241313 7.315524443407491 0.03034555087996904 0.065757718314512 4.832184311125211e-06 5.315856509035506 0.45524949555321825 EVVYWS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 EVVYWSPK 8 0 E6ZCI6;C0MHM2;Q86VZ5 E6ZCI6 SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 1 EVVY(0.002)WS(0.998)PK 73.067 0.030964999999999996 2029100.0 16309.0 29049.0 17471.0 11827.0 17898.0 15744.0 15297.0 12911.0 19100.0 12462.0 True False 16076.430669295692 28981.73882526524 16034.601820010292 12696.797033715426 16845.274828821883 15070.665821056546 16089.003811204153 13510.892193922788 16948.75686808342 14616.040095428774 1.0999169791771206 1.982872148409705 1.0970551336285113 0.8686892585691798 1.1525197467192438 1.0311045757030974 1.1007772082012865 0.9243880083599644 1.1595997792441888 1.0 13.835264876303796 -5.484434947287372 22.06068233673348 1.0340680708592545 1.5410383638815255 0.46444009014462295 0.2155443274499652 100.43060699496748 57630.245323365634 0.050969048088406355 0.10602614536801996 3.2776686913307516e-06 5.484434947287372 0.506970293022271 EVYELLDS(ph)PGK ddPTM_PC-9_AZD4547_30min_R2 4 EVYELLDSPGK 11 0 E9PBS1;P22234;P22234-2 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 1 EVYELLDS(1)PGK;EVYELLDS(1)PGK;EVYELLDS(1)PGK;EVYELLDS(1)PGK 179.59 7.299e-05 15878200.0 135397.5 149808.0 137735.1 148311.3 147488.4 155271.7 139698.6 164982.2 129036.7 132351.4 True False 178451.08855704672 198230.5063448906 135908.6425794844 114120.42117174332 127012.18149509889 145562.53605318768 152131.50476795217 139487.9919037986 135857.3165283559 127717.817770631 1.397229389540055 1.5520975053057489 1.064132201378224 0.8935356331932691 0.9944750365465893 1.1397198808595688 1.1911533364997342 1.0921576514430094 1.0637303306602268 1.0 16.96260028229785 -5.268559381887756 24.77046982334564 1.0581340461701467 1.4746634564792231 0.7963376870997805 0.08490702849937108 196.41044958797735 683313.5758322104 0.02451554439313504 0.052837974013243263 5.38816167005235e-06 5.268559381887756 0.4165294103090764 EVYELLDS(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 EVYELLDSPGK 11 0 E9PBS1;P22234;P22234-2 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 1 EVYELLDS(1)PGK;EVYELLDS(1)PGK;EVYELLDS(1)PGK;EVYELLDS(1)PGK;EVYELLDS(1)PGK 151.55 1.2239e-07 9130400.0 160540.0 196802.0 145268.6 160897.3 176243.0 123507.8 152568.5 120107.0 110166.3 104683.0 True False 187716.25119046684 216339.2019408923 148732.35435823363 151882.74591708457 141709.4493209614 117030.83354494435 138116.1071797142 116954.3185138854 111777.27372333688 123661.19922982778 1.5179882805567084 1.7494509457151541 1.202740676012776 1.2282166666911118 1.1459491756795148 0.9463828126673695 1.1168912159991395 0.9457640653841837 0.9038993186180874 1.0 16.9160333760465 -5.546502238926676 0.8472696725914242 0.9814579372734177 1.7336383339017425 0.8194654537089703 0.10951933209107276 0.37601356912768097 0.4232693519784975 0.044648901750891444 0.21588455773209148 2.8411735377890316e-06 5.546502238926676 0.7521803966283248 EVYELLDS(ph)PGK ddPTM_PC-9_Lapatinib_30min_R1 6 EVYELLDSPGK 11 0 E9PBS1;P22234;P22234-2 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 1 EVYELLDS(1)PGK;EVYELLDS(1)PGK;EVYELLDS(1)PGK;EVYELLDS(1)PGK;EVYELLDS(1)PGK;EVYELLDS(1)PGK 195.72 5.8033999999999994e-05 11667700.0 76798.7 112048.2 94511.9 100204.2 104015.2 95926.7 99613.90000000001 84035.09999999999 89750.09999999999 79374.5 True False 75703.53645484317 111788.75927712097 86741.49640848424 107573.55113941232 97897.23043775144 91824.13865705945 104771.42032744407 87939.67753121509 79641.49862754847 93094.27656512693 0.8131921665654973 1.2008123743129981 0.931759712937901 1.1555334560675807 1.051592364749346 0.9863564339835766 1.125433530321792 0.9446303336348955 0.8554929644018754 1.0 16.506404853188208 -7.92859019530793 8.280205300245575 0.9186082519952532 1.042874661843549 0.15555398568677048 0.1111039805388883 0.3857051594620216 39.45725254695336 0.05600958197609297 0.026776633812326447 1.1787176989347788e-08 7.92859019530793 0.12426640984829573 EVYELLDSPGK ddPTM_PC-9_Lapatinib_30min_R1 1 EVYELLDSPGK 11 0 E9PBS1;P22234;P22234-2 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 0 95.775 0.028011 2196800.0 20759.0 23099.0 27585.0 21582.0 24111.0 20037.0 21779.0 21010.0 24696.0 20868.0 False True 20462.972853265626 23045.51568469833 25317.06778117929 23169.212275441463 22692.838384049846 19180.064218528332 22906.610054534587 21986.201300775898 21914.476419591014 24475.00599513784 0.8360763162767259 0.9415938729198478 1.0344049675088427 0.946647869260756 0.9271841808152351 0.7836592245304703 0.9359184655188715 0.8983123969466499 0.8953818611502896 1.0 14.579021592765736 -4.755059201166753 24.80381248015656 0.9254823647270106 0.836076150929202 0.16115964198371735 0.06324115116044121 415.92516287169974 1616798.302944411 0.01667310193779688 0.152565597337383 1.757683997660532e-05 4.755059201166753 -0.08940621379780866 EVYQQQQYGS(ph)GGR ddPTM_PC-9_AZD4547_30min_R2 3 EVYQQQQYGSGGR 13 0 Q99729-3;Q99729-4;D6R9P3;D6RD18;D6RBZ0;Q99729-2;Q99729 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 1 EVYQQQQYGS(1)GGR;EVYQQQQYGS(1)GGR;EVYQQQQYGS(1)GGR 204.17 9.918799999999999e-10 28981000.0 22146.9 28268.0 27778.7 39689.1 33662.3 34098.5 23834.6 32890.3 25429.9 28446.4 True False 29189.15351586298 37405.07818913124 27410.33628771986 30539.391185482385 28988.87069859366 31966.315404607594 25955.83322626163 27807.859878905198 26774.07259783021 27450.500194410306 1.0633377646723798 1.3626373991082308 0.9985368606617002 1.1125258545088756 1.056041620126711 1.1645075746604003 0.9455504651076256 1.013018330520901 0.9753582779261037 1.0 14.744544817356264 -6.2493448877621764 0.47395710761631793 0.975942961440663 1.211017778861582 0.3021304812865433 0.09681377094058312 1.6888168117195952 0.7135845835038291 0.08119885558896012 0.19072072537347043 5.631902300081358e-07 6.2493448877621764 0.23507481742091896 EVYQQQQYGS(ph)GGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EVYQQQQYGSGGR 13 0 Q99729-3;Q99729-4;D6R9P3;D6RD18;D6RBZ0;Q99729-2;Q99729 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 1 EVYQQQQYGS(1)GGR;EVYQQQQYGS(1)GGR;EVYQQQQYGS(1)GGR;EVYQQQQYGS(1)GGR 193.98 1.3594e-06 22496300.0 32324.7 43058.1 46498.0 41739.9 52530.7 39817.6 45150.0 30548.4 39875.5 29476.2 True False 37796.63326807323 47332.62360693063 47606.688664646965 39401.34872558164 42237.686429785164 37729.49496112128 40873.065142307256 29746.536868705294 40458.60375046552 34820.00172652919 1.085486254852083 1.3593515582989801 1.3672224670906796 1.1315722794913576 1.2130294180199443 1.0835581013878974 1.1738386879850804 0.8542945259546484 1.1619357192518547 1.0 15.087628654073646 -6.842589183727984 0.9569344832971379 1.0169535153306457 1.2651280443277164 0.3855241915632275 0.11469099161773377 0.5321559838843175 1.0395422399739003 0.06878624301209264 0.05801618687005449 1.4368479618427885e-07 6.842589183727984 0.2481745289970707 EVYQQQQYGS(ph)GGR ddPTM_PC-9_Lapatinib_30min_R1 4 EVYQQQQYGSGGR 13 0 Q99729-3;Q99729-4;D6R9P3;D6RD18;D6RBZ0;Q99729-2;Q99729 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 1 EVYQQQQYGS(1)GGR;EVYQQQQYGS(1)GGR;EVYQQQQYGS(1)GGR;EVYQQQQYGS(1)GGR 208.79 2.6813000000000004e-47 25722000.0 43381.8 43650.1 51146.0 39869.0 40095.8 40663.8 34389.1 35471.4 43129.2 26442.300000000003 True False 42763.16757675224 43549.03087530413 46940.97330926943 42801.099259085175 37737.44387537579 38924.70406594763 36169.59933084139 37119.530738712165 38271.53532538972 31012.81632284999 1.378886945692987 1.404226898387734 1.5135991785010412 1.3801100426841812 1.216833823878522 1.255116712417641 1.1662790942398844 1.1969093794091443 1.2340554603933718 1.0 14.920576924865209 -6.257656943015634 2.5611469875245314 1.1849511010427178 1.432968734754588 0.7296271212349702 0.07251104407091245 0.15328928817681486 1.9913470254407017 0.02297391138635387 0.029140700190585424 5.525137074165837e-07 6.257656943015634 0.24801763371187024 EWFLQAAK ddPTM_PC-9_Lapatinib_30min_R1 2 EWFLQAAK 8 0 P06744-2;P06744;A0A2U3TZU2;K7EQ48;A0A0J9YXP8;A0A2R8Y6C7;A0A0J9YYH3;A0A0J9YX90;K7ERC6 P06744-2 GPI Glucose-6-phosphate isomerase 0 ; 163.77 0.00033126 16792700.0 101093.0 109166.0 108615.0 102258.0 109633.0 101984.0 112171.0 108360.0 101931.0 113166.0 False True 99651.39528181436 108913.23283413883 99685.09396602462 109778.394442688 103184.60248677105 97622.38205631558 117978.66552308187 113394.80118762839 90450.4573989848 132726.59231578335 0.7508020325325884 0.8205833581187127 0.7510559280302599 0.8271017324207575 0.7774222232819333 0.7355148682191149 0.8888849134496486 0.8543487722327661 0.6814795424249641 1.0 17.018097923958763 -11.76293119681554 2.5642125013735777 1.8597504876605455 0.7916615274708526 0.5415004080794436 0.058556082057463744 3576423.8113041786 1810501.6252505858 17757957.0848455 0.014356147176257413 1.7261113298399305e-12 11.76293119681554 -1.068088960189693 EWNGVVSESDS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 2 EWNGVVSESDSPVK 14 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;F5GZ28;M0QY71;M0R1G7 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 EWNGVVS(0.003)ES(0.012)DS(0.985)PVK;EWNGVVS(0.014)ES(0.046)DS(0.941)PVK 98.421 0.0024576999999999997 19670400.0 69030.0 89803.0 88345.0 98763.0 96060.0 94513.0 82682.0 86710.0 97040.0 85035.0 True False 90980.10408680298 118830.06355662075 87173.4875764024 75994.71622313927 82723.7271162964 88603.08716910341 90040.53782374217 73310.96189757677 102169.33628891347 82057.95053263953 1.1087299097314716 1.4481237075175875 1.0623405411731324 0.9261103370222665 1.0081134927125928 1.0797623703002486 1.0972798764688556 0.8934047392326288 1.2450875951169948 1.0 16.32435550168971 -5.407990234579344 7.714493726019131 1.031525210074672 1.2770121094847524 0.3941029268970708 0.1190196957241813 0.235825619319401 14.312691222658358 0.029103811275654 0.06085655259380879 3.908496842270406e-06 5.407990234579344 0.2454868994100805 EWNGVVSESDS(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EWNGVVSESDSPVK 14 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;F5GZ28;M0QY71;M0R1G7 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 EWNGVVS(0.003)ES(0.03)DS(0.967)PVK;EWNGVVS(0.024)ES(0.045)DS(0.931)PVK 98.421 0.0024576999999999997 19682900.0 50223.0 67113.0 55338.0 49694.0 66849.0 51476.0 60614.0 48804.0 49041.0 48626.0 True False 58724.761950534514 73775.53510563466 56657.467790533694 46909.80629012175 53750.41832956171 48776.50794168104 54872.2031126426 47522.94671211234 49758.131848543104 57441.5088767958 1.022340170006521 1.2843592821329453 0.9863506181924335 0.8166534481316792 0.9357417550581588 0.8491508822705196 0.9552709214226247 0.8273276179781868 0.8662399860572518 1.0 15.809806026002885 -5.485839716542676 6.180991697537988 0.8888720083372227 1.1515529263311621 0.6227463003485856 0.08029700996648638 0.10753164424588534 11.867690593552405 0.019456137478005443 0.039623484395848084 3.267083869800032e-06 5.485839716542676 0.26268091799393944 EWNGVVSESDS(ph)PVKRPGR ddPTM_PC-9_AZD4547_30min_R2 1 EWNGVVSESDSPVKRPGR 18 2 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;F5GZ28;M0QY71;M0R1G7 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 EWNGVVS(0.001)ES(0.036)DS(0.963)PVKRPGR 57.788000000000004 0.01066 62800000.0 172780.0 173680.0 199590.0 212380.0 214190.0 235050.0 215280.0 251350.0 206330.0 225300.0 True False 227720.44595274306 229818.6635024873 196943.3061902105 163419.0722382907 184453.41568852295 220352.28634259617 234439.50294737905 212509.63294840185 217236.1825689567 217412.3155759827 1.0474128172061064 1.0570636851626225 0.9058516564181547 0.7516550835924376 0.8484037125489284 1.0135225585488326 1.078317492393597 0.9774498394233447 0.9991898664684224 1.0 17.730074140271917 -6.841105632462342 11.068485815051707 1.0165403495262548 0.9192457937296692 0.21884012516505402 0.08638881807369195 0.8344678032067234 111.10624768834442 0.035060703283230216 0.030927613804017248 1.4417646317311325e-07 6.841105632462342 -0.09729455579658564 EWNGVVSESDS(ph)PVKRPGR ddPTM_PC-9_Lapatinib_30min_R1 3 EWNGVVSESDSPVKRPGR 18 2 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;F5GZ28;M0QY71;M0R1G7 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 EWNGVVS(0.003)ES(0.076)DS(0.92)PVKRPGR;EWNGVVS(0.004)ES(0.045)DS(0.95)PVKRPGR;EWNGVVSES(0.004)DS(0.996)PVKRPGR 79.69 0.0014716 152240000.0 388826.0 496889.0 575865.0 531456.0 638362.0 587727.0 514169.0 546557.0 567192.0 474256.0 True False 383281.269938044 495738.48404926853 528519.6026031835 570541.0471252431 600814.8022279803 562591.2862685525 540790.1549717607 571952.033524426 503308.86416345387 556230.5176936036 0.6890691138762226 0.891246467570381 0.9501808796731923 1.0257276955802026 1.080154330113429 1.01143549009379 0.972241072306018 1.0282643891888767 0.904856616372672 1.0 19.085323375031884 -4.64820172558744 1.3817346875767398 1.005093091022102 0.480164470244535 0.8239559929842941 0.043777124626668815 0.6812909748464266 0.9356419696511346 0.013099585528534864 0.5455919182816175 2.2480101842992e-05 4.64820172558744 -0.5249286207775671 EWPVSSFNRPFPNS(ph)P ddPTM_PC-9_AZD4547_30min_R2 2 EWPVSSFNRPFPNSP 15 1 Q96H12 Q96H12 MSANTD3 Myb/SANT-like DNA-binding domain-containing protein 3 1 EWPVSSFNRPFPNS(1)P;EWPVSSFNRPFPNS(1)P 152.9 0.00045102 17467000.0 38803.0 36901.0 54353.0 72225.0 58084.0 51963.0 50658.0 61950.0 53803.0 53573.0 True False 51141.54684746084 48828.52661161499 53632.243706380694 55574.64211512646 50020.03920282077 48713.74539553425 55166.46386245049 52377.05096937931 56646.916738998516 51697.425576352085 0.9892474582110425 0.9445059607368647 1.0374258119907938 1.0749982517610688 0.9675537736196559 0.9422857106025284 1.0671027279873921 1.0131462134806593 1.0957396061306093 1.0 15.657804818683356 -7.286598536611384 24.843123418914978 1.0450926547050694 0.9951152038387799 0.23525686096113585 0.045189916600443074 1209.0977828682417 1193903.0181326112 0.019770945610636272 0.013336812875992244 5.168939671427487e-08 7.286598536611384 -0.04997745086628946 EWPVSSFNRPFPNS(ph)P ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EWPVSSFNRPFPNSP 15 1 Q96H12 Q96H12 MSANTD3 Myb/SANT-like DNA-binding domain-containing protein 3 1 EWPVSS(0.001)FNRPFPNS(0.999)P;EWPVSSFNRPFPNS(0.999)P;EWPVSSFNRPFPNS(1)P;EWPVSSFNRPFPNS(1)P 142.57 0.00044307 14597800.0 53867.3 55010.8 62167.0 69661.0 79071.0 72498.0 75282.0 70143.0 63878.0 52697.6 True False 62985.969962328534 60471.90867028828 63649.297049660396 65758.12001400926 63577.60516592288 68696.077254565 68150.74396551878 68301.82057265163 64812.094904696794 62251.25772602792 1.01180236774547 0.9714166569361429 1.0224580092788702 1.0563339989597524 1.0213063557001902 1.1035291456584087 1.0947689485320105 1.0971958329461013 1.0411371154931406 1.0 15.925815365272705 -5.785663635887859 1.2468747394118125 1.0707166348845487 0.9889716757902397 0.37631784744754493 0.03377558200234121 0.44879934655880876 1.384031517573066 0.01179411535912722 0.029431678280968054 1.6380847383237408e-06 5.785663635887859 -0.08174495909430901 EWPVSSFNRPFPNS(ph)P ddPTM_PC-9_Lapatinib_30min_R1 1 EWPVSSFNRPFPNSP 15 1 Q96H12 Q96H12 MSANTD3 Myb/SANT-like DNA-binding domain-containing protein 3 1 EWPVSSFNRPFPNS(1)P 91.789 0.018317 5884200.0 15605.0 9717.4 18291.0 10961.0 9621.3 15590.0 13217.0 10032.0 12320.0 11539.0 True False 15382.469838393483 9694.899957335276 16787.184585301813 11767.108504824106 9055.394050203597 14923.25204206501 13901.311588722321 10498.123343616562 10932.391864648574 13533.50077524897 1.1366216394302087 0.7163630547881594 1.2404170113917172 0.8694800185288815 0.6691095083664345 1.1026897097724868 1.0271778026677347 0.7757138022126749 0.8078022121698557 1.0 13.724247455952558 EWQELDDAEK ddPTM_PC-9_AZD4547_30min_R2 1 EWQELDDAEK 10 0 Q13200;Q13200-3;Q13200-2 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 0 119.27 0.0037013000000000007 1694500.0 14187.0 13669.0 12944.0 14034.0 16563.0 13153.0 14572.0 13173.0 13896.0 13556.0 False True 18698.17089206832 18087.236938136226 12772.354102540643 10798.678123138596 14263.513348190894 12330.540830734602 15868.879770295478 11137.41553542589 14630.51419075373 13081.40856612527 1.4293698417529621 1.3826673822399913 0.9763745270990974 0.8254981157841152 1.0903652520361395 0.9426003911126922 1.2130864723076118 0.8513926829153999 1.1184203992099078 1.0 13.67523027374576 -5.2448846005142356 7.000233115793756 0.9989216228073915 1.409068493923605 0.6760522510700822 0.11181186761556228 0.0882676260531537 22.266206882491588 0.027565610776519686 0.06920880820890105 5.690041048991163e-06 5.2448846005142356 0.4101468711162134 EWQELDDAEK ddPTM_PC-9_Lapatinib_30min_R1 3 EWQELDDAEK 10 0 Q13200;Q13200-3;Q13200-2 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 0 ;; 136.5 0.00053199 10904100.0 71549.0 73496.0 72316.0 89427.0 87095.0 77203.0 76939.0 79553.0 88199.0 82693.0 False True 70528.69813952043 73325.82452758073 66370.45762783264 96003.7598997267 81972.2433353582 73901.20765898295 80922.52495458181 83249.32280250482 78265.09984335542 96986.37486850383 0.7272021274652726 0.7560425330568075 0.6843276462061718 0.9898685256551822 0.8451933938813354 0.7619751512434584 0.834370034598141 0.8583610111768379 0.8069700506846337 1.0 16.56549446406234 -14.522878745280336 0.041324687437878614 1.790105458989453 0.3534094175692923 0.4023206144597409 0.07645465189185119 897.003546758231 2.7552308823313463 88.00794114039371 25.349636210796096 3.0000000000000132e-15 14.522878745280336 -1.4366960414201606 EWQHEEFYR ddPTM_PC-9_AZD4547_30min_R2 2 EWQHEEFYR 9 0 I3L239;I3L0K7;Q12931-2;Q12931 I3L239 TRAP1 Heat shock protein 75 kDa, mitochondrial 0 ; 137.46 0.00032234 3127300.0 36676.0 39034.0 52923.0 62950.0 55049.0 53200.0 42749.0 65080.0 49156.0 52556.0 False True 48338.205091809265 51650.97714852656 52221.20644072613 48437.850067804946 47406.39656490737 49873.395589985594 46553.578184213664 55023.38138962396 51754.285806037085 50716.030436801375 0.9531149160430609 1.0184349347469188 1.0296785058089353 0.955079678961954 0.9347418588681102 0.9833852365897245 0.9179263002893207 1.084930758888752 1.0204719367879058 1.0 15.630154209150243 -7.7665344575752755 24.999999110193063 1.039525997948696 0.9730155585010574 0.37386571019073955 0.03819102272885814 140.25462518929712 688168.4452149599 0.020719766347771108 0.010440427674486498 1.7118493506207767e-08 7.7665344575752755 -0.06651043944763857 EWQHEEFYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EWQHEEFYR 9 0 I3L239;I3L0K7;Q12931-2;Q12931 I3L239 TRAP1 Heat shock protein 75 kDa, mitochondrial 0 ; 94.40899999999999 0.0048315 4109600.0 21988.4 21782.9 30249.0 25970.3 30348.0 21537.2 24511.0 21091.4 23545.0 21300.8 False True 25710.601829303974 23945.362353829103 30970.25087997133 24515.26828784861 24401.52725494084 20407.75131792626 22189.140635727435 20537.77309818552 23889.301082236227 25162.46642295997 1.0217838504831087 0.9516301761253302 1.2308114140874495 0.9742792250873781 0.9697589594267756 0.8110393860001268 0.8818348830653793 0.816206676760647 0.9494022040875127 1.0 14.618985721551049 -6.325948108544418 2.440816611619391 0.8816209017676081 1.056842380866999 0.39912652820568306 0.08777080237049914 0.27398388654101863 3.2044783426942476 0.028913700545186473 0.03514342170995785 4.721194488461525e-07 6.325948108544418 0.175221479099391 EWQHEEFYR ddPTM_PC-9_Lapatinib_30min_R1 2 EWQHEEFYR 9 0 I3L239;I3L0K7;Q12931-2;Q12931 I3L239 TRAP1 Heat shock protein 75 kDa, mitochondrial 0 ; 154.85 8.0833e-13 0.0 47727.0 48568.0 49649.0 36635.0 40810.0 36041.0 31751.2 31939.0 45245.0 30204.0 False True 47046.40422794011 48455.54378000902 45567.05087068232 39329.26011077742 38409.63603554702 34499.610445674494 33395.12177618524 33423.00253905196 40149.03164902797 35424.72115569981 1.3280670303983573 1.3678454536603337 1.286306550456802 1.110220739294355 1.0842607868874343 0.9738851660692193 0.9427066942716638 0.943493736821531 1.133361966988074 1.0 15.11246887662013 -5.879761800333062 1.406336551102943 0.9959848734768029 1.3606348518956362 0.8674670301534319 0.05547163967912744 0.14026413575981936 0.5628468420415962 0.019429610654868958 0.03989931553113695 1.318979967742483e-06 5.879761800333062 0.3646499784188333 EWSLESS(ph)PAQNWTPPQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EWSLESSPAQNWTPPQPR 18 0 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;E5RHT6;E5RHC5;F8W1U7;Q8N6T3-3 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 EWSLES(0.02)S(0.542)PAQNWT(0.438)PPQPR 84.821 0.0019069000000000002 6522400.0 12958.0 11416.0 14707.0 11059.0 13042.0 13302.0 13575.0 13556.0 12866.0 8361.5 True False 15151.533467833986 12549.305034284364 15057.670656608092 10439.400083761755 10486.513722780368 12604.419703167317 12289.077725510992 13200.169363769259 13054.140909919364 9877.373760402423 1.533963767633785 1.2705102933933201 1.5244609571192955 1.056900380302753 1.0616702351408365 1.2760901843866026 1.244164493883677 1.3364047654739613 1.3216206277677107 1.0 13.269911787352735 -5.75444903289387 24.999735088926887 1.2003700693762087 1.4257315353655056 0.4515463797189806 0.12898970980633065 174.5634221778623 624287.8203062884 0.03623221855855287 0.061042851141017096 1.7601552166306362e-06 5.75444903289387 0.22536146598929685 EWSLESSPAQNWT(ph)PPQPR ddPTM_PC-9_AZD4547_30min_R2 1 EWSLESSPAQNWTPPQPR 18 0 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;E5RHT6;E5RHC5;F8W1U7;Q8N6T3-3 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 EWS(0.002)LES(0.014)S(0.185)PAQNWT(0.799)PPQPR 130.95 0.00010034 11313000.0 10117.0 10472.0 12556.0 17343.0 15133.0 16794.0 12100.0 15104.0 11448.0 13079.0 True False 13333.995553327351 13856.869208878674 12389.499236055344 13344.839296678967 13032.04416459415 15743.868525154481 13176.876559194026 12770.023855391524 12053.117908444785 12621.10819093777 1.0564837375295975 1.097912243461173 0.9816490793535289 1.0573429127452414 1.0325594208875764 1.2474236245323467 1.044034831161285 1.0117989373199954 0.9549967979118653 1.0 13.623550970644718 -7.782347351595461 3.354647011219258 0.9817877280778297 1.0767778339431802 0.2721132463003879 0.0657207884950833 0.33900626395332384 7.862327945784923 0.040508840264858244 0.01884519025280867 1.6506410765017534e-08 7.782347351595461 0.0949901058653505 EWSLESSPAQNWT(ph)PPQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EWSLESSPAQNWTPPQPR 18 0 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;E5RHT6;E5RHC5;F8W1U7;Q8N6T3-3 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 EWSLESS(0.003)PAQNWT(0.997)PPQPR 123.92 0.00011058 7521600.0 9852.9 14531.0 10119.0 11242.0 18904.0 12223.0 13177.0 9197.8 10904.0 12199.0 True False 11520.80136635449 15973.541647966553 10360.275336521197 10612.14718705575 15199.896903499468 11582.004362638269 11928.779166781449 8956.36749587466 11063.450371658697 14410.582132769137 0.7994681450207767 1.1084591518092322 0.7189352408576409 0.7364134973370795 1.0547732744907965 0.8037152320377963 0.8277791318128531 0.6215132333556607 0.7677309819775299 1.0 13.814840995637805 -6.979657442392289 24.985452799082324 0.7788626064665308 0.8838222139779461 0.0586681028594489 0.14556647384598762 569.0832503024001 698966.1150663748 0.05108233354037474 0.045045722540803274 1.0479548154082328e-07 6.979657442392289 0.10495960751141531 EWSLESSPAQNWT(ph)PPQPR ddPTM_PC-9_Lapatinib_30min_R1 2 EWSLESSPAQNWTPPQPR 18 0 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;E5RHT6;E5RHC5;F8W1U7;Q8N6T3-3 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 EWS(0.001)LES(0.001)S(0.016)PAQNWT(0.982)PPQPR;EWS(0.003)LES(0.017)S(0.29)PAQNWT(0.689)PPQPR 143.99 0.00047041 15797800.0 43552.0 35079.0 45449.0 40376.0 39633.0 36146.0 33245.0 32120.0 35457.0 26420.0 True False 42930.94049354134 34997.77673074733 41712.35865821347 43345.38573038756 37301.864861475995 34600.11984044144 34966.2634309657 33612.41245982496 31463.45928123737 30986.66179756287 1.3854651647864147 1.1294465005423702 1.3461391527335864 1.3988401207450079 1.2038039174781268 1.116613337263802 1.1284295049076836 1.084738094068223 1.015387184550225 1.0 14.919359720872183 -6.713743317528967 2.101974599274589 1.067531526899098 1.3040916545749004 0.6880569495224883 0.07820720142570592 0.20172090929727776 1.8318712941902848 0.031153158495114866 0.02959341213354827 1.933110511998705e-07 6.713743317528967 0.23656012767580248 EWSQHINGASHSR ddPTM_PC-9_AZD4547_30min_R2 2 EWSQHINGASHSR 13 0 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991;H0Y8T4 A0A0R4J2E8 MATR3 Matrin-3 0 ; 94.023 0.0016289000000000002 3269900.0 1642.53 1596.6599999999999 15103.2 21527.0 18967.0 21217.8 7687.6 23499.9 11286.3 17338.6 False True 2164.8203732536103 2112.7491206119385 14902.921699744433 16564.282738834587 16333.759444251464 19891.047611826987 8371.78150714545 19868.530428980106 11882.87077656188 16731.580891459103 0.1293852856641106 0.12627313188859662 0.8907061320996787 0.990001055267293 0.9762233198531339 1.1888325281910859 0.5003580690584328 1.187486738872494 0.7102060978964443 1.0 14.030286145100026 -5.270820539230799 5.542676449120126 0.9373119222402829 0.11983372399026969 0.7322914053856371 0.1942283086417068 0.07091128131813179 8.241076825295899 0.04780211856722051 0.11280566702686526 5.360181071372524e-06 5.270820539230799 -0.8174781982500132 down EWYQETHEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EWYQETHEK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 0 ; 108.43 0.00099696 3920100.0 57992.0 63718.0 70815.0 79057.0 91368.0 70271.0 81795.0 75682.0 64088.0 64659.0 False True 67808.90020579014 70043.50194240814 72503.49816738309 74627.69259625203 73465.09629067605 66585.86505497452 74046.78545548233 73695.42769170731 65025.16575741586 76381.16485963752 0.8877699146170359 0.9170258410057527 0.9492326845318443 0.9770431327329484 0.9618221511242961 0.871757653569916 0.9694377611490348 0.9648377034722413 0.8513246148695153 1.0 16.220929301662373 -4.9524558691851785 2.9870280031018237 0.9420333190744815 0.8871279048470735 0.13532726660149208 0.04415282642284046 0.6067378661142238 9.859054200353897 0.011214737194202485 0.06621482093650394 1.115691516535708e-05 4.9524558691851785 -0.05490541422740802 EY(ph)FTFPASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EYFTFPASK 9 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 EY(0.985)FT(0.015)FPASK;EY(0.995)FT(0.005)FPASK 99.815 0.0058284 9958600.0 55040.0 48586.0 80662.0 60988.0 101083.0 71862.0 84712.0 62941.0 69546.0 55335.0 True False 64357.18491044775 53409.296986312205 82585.2879923385 57571.04008576381 81276.51178038692 68093.43021417914 76687.46609823112 61288.86544150199 70562.97868189422 65366.79746838102 0.9845546577615091 0.817070730934113 1.263413402381941 0.8807382695107843 1.2433913688321918 1.0417128091232715 1.1731868328921284 0.9376146272294954 1.0794926692871358 1.0 15.996270396142135 -5.237868079513579 24.937980877449903 1.0762605169328563 0.9008127004742393 0.24859135871493743 0.12282116943644693 1003.2805985877021 1061447.961023209 0.028708932731226645 0.07584675991631254 5.782716754618716e-06 5.237868079513579 -0.17544781645861696 EY(ph)FTFPASK ddPTM_PC-9_Lapatinib_30min_R1 2 EYFTFPASK 9 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 EY(1)FTFPASK;EY(0.998)FT(0.002)FPASK 129.38 0.0018846 12055600.0 107125.0 81311.0 110670.0 60647.0 111828.0 84373.0 85768.0 77973.0 108882.0 60380.0 True False 105597.37785568087 81122.72937523277 101571.13979855394 65107.18269246129 105250.49690230702 80764.56347306928 90208.64737395299 81595.91023443126 96618.56258170983 70816.60254870732 1.4911387168432924 1.1455326357888596 1.4342842799990834 0.9193773825520771 1.4862404169970767 1.1404749813791166 1.2738347241652537 1.1522144143855246 1.3643490241607685 1.0 16.111800011138982 -13.671038439335735 0.26672230583140666 9.523933351303751e-29 1.277701240540286 0.17159941940590062 0.1738838964656743 222.10866137156674 3.299454708664371 121.89530322723753 0.20340507317042603 2.1328561260343936e-14 13.671038439335735 1.277701240540286 EY(ph)S(ph)S(ph)VFSHGVSIT(ph)RK ddPTM_PC-9_AZD4547_30min_R2 1 EYSSVFSHGVSITRK 15 1 F5GXW1;H0Y599;Q8N1I0-2;Q8N1I0;Q8N1I0-3 F5GXW1 DOCK4 Dedicator of cytokinesis protein 4 4 EY(0.989)S(0.96)S(0.961)VFS(0.149)HGVS(0.163)IT(0.778)RK 46.702 0.045084 0.0 8372.7 11528.0 11938.0 19908.0 13035.0 12282.0 9609.3 17395.0 15410.0 12146.0 True False 11035.044437021244 15254.200557673168 11779.694319849366 15318.518175533929 11225.315250478076 11514.00459842487 10464.509084319265 14707.002447334191 16224.541139861481 11720.772236954677 0.9414946570012352 1.30146719425004 1.005027150234087 1.306954684029764 0.957728298403883 0.9823588724062152 0.892817373528127 1.254781011865768 1.3842553043311236 1.0 13.516780006111839 EY(ph)VMS(ph)MGVCPVSSSALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EYVMSMGVCPVSSSALK 17 0 Q6ZPD8 Q6ZPD8 DGAT2L6 Diacylglycerol O-acyltransferase 2-like protein 6 2 EY(0.998)VMS(0.963)MGVCPVS(0.037)S(0.002)S(0.001)ALK 53.236999999999995 0.038922000000000005 0.0 3870.3 2350.6 3999.8 4166.1 6926.4 8210.2 6990.0 5183.4 9072.1 4544.7 True False 4525.465348090593 2583.9520334257913 4095.17040132597 3932.686923678436 5569.221641578432 7779.642658768931 6327.856596782455 5047.3412422662705 9204.762299773001 5368.618134174592 0.842947893664329 0.4813067290030055 0.7627978557941502 0.7325324367260243 1.037365948255264 1.4490959245632817 1.1786751150173476 0.9401565013791547 1.7145496419607433 1.0 12.390335075381872 -6.376261347937524 2.8938627080644466 1.2486100609125477 0.6857486840728041 0.5737888804642108 0.22318810546334322 0.1917089834781899 3.0946297869855575 0.07125832559899697 0.08278285988310095 4.204735214181783e-07 6.376261347937524 -0.5628613768397436 EY(ph)VNASEVSSGKPVSAR ddPTM_PC-9_AZD4547_30min_R2 2 EYVNASEVSSGKPVSAR 17 1 O15231-7;O15231;O15231-8;O15231-6;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 EY(0.994)VNAS(0.006)EVSSGKPVSAR;EY(0.996)VNAS(0.004)EVSSGKPVSAR 111.73 0.0014325999999999998 27678000.0 20003.9 24540.0 32598.0 45594.0 37653.0 33394.0 29811.0 33145.0 35322.0 33428.0 True False 26364.72409303204 32472.075094144628 32165.729220845173 35083.007720277965 32425.530888089845 31305.86790097704 32464.121248440744 28023.20184632895 37189.04880870783 32257.695894691304 0.8173157865677233 1.0066458311267237 0.9971490005316447 1.087585667457781 1.0052029442507753 0.9704929950105051 1.0063992590922592 0.8687291844344273 1.1528736872625822 1.0 14.977355772785177 -4.761436024319611 11.86445061031042 1.0069173553264867 0.8170356244908117 0.4090702810541317 0.06955559666456583 0.06053410500187856 428.4753377345851 0.01644073176062661 0.09207016589873207 1.7320641613735517e-05 4.761436024319611 -0.18988173083567506 EY(ph)VNASEVSSGKPVSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EYVNASEVSSGKPVSAR 17 1 O15231-7;O15231;O15231-8;O15231-6;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 EY(0.986)VNAS(0.014)EVSSGKPVSAR 120.9 0.00036931 9286400.0 12689.0 10915.0 23500.0 16184.0 26583.0 19835.0 23354.0 20869.0 21086.0 12533.0 True False 14836.997080826162 11998.569065278021 24060.3291242463 15277.262949235943 21374.251977662185 18794.817682478104 21141.74005168204 20321.210862533248 21394.342859207194 14805.133688826592 1.0021521853614612 0.8104330104315991 1.6251342020913047 1.031889564142583 1.4437054353513399 1.269479768133571 1.4280006176261464 1.3725786804525533 1.4450624566364751 1.0 13.853809897510802 -5.24452305488176 24.98841993565449 1.33547165822515 0.9062925415426063 0.4502748131515002 0.18574285601848733 657.8527208518308 971761.9703338537 0.043189146405137276 0.11359659725493249 5.694779921152879e-06 5.24452305488176 -0.4291791166825437 EY(ph)VNASEVSSGKPVSAR ddPTM_PC-9_Lapatinib_30min_R1 2 EYVNASEVSSGKPVSAR 17 1 O15231-7;O15231;O15231-8;O15231-6;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 EY(0.999)VNAS(0.001)EVSSGKPVSAR;EY(0.999)VNAS(0.001)EVSSGKPVSAR 114.58 0.00076984 22721000.0 32859.0 24940.0 47994.0 29596.0 42978.0 40857.0 35972.0 32951.0 43746.0 30893.0 True False 32390.42463439741 24882.252962309034 44048.118582197574 31772.588569361786 40450.11853799905 39109.64135231879 37834.45414765222 34482.0237535396 38818.86481419776 36232.813887665005 0.893952778131436 0.6867325579363814 1.2156968740756067 0.8769009403428739 1.1163946212791873 1.0793984003995107 1.0442041367516441 0.9516794323633407 1.071373173901162 1.0 15.145009231273292 -5.251219689641109 24.994437088457687 1.040554297414912 0.7903426661131182 0.5162619995560043 0.0983334281739956 516.0484778494681 1262100.901828051 0.023252982178653323 0.060074201797342734 5.60764239388313e-06 5.251219689641109 -0.2502116313017938 EYAENIGDGRS(ph)PEFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EYAENIGDGRSPEFR 15 1 A0A087WUB9;Q8WYA6-3;Q8WYA6-2;Q8WYA6-4;Q8WYA6 A0A087WUB9 CTNNBL1 Beta-catenin-like protein 1 1 EYAENIGDGRS(1)PEFR 61.957 0.021221 5284700.0 16769.0 23412.0 25422.0 25572.0 21539.0 17238.0 20282.0 21456.0 15806.0 14920.0 True False 19607.660497152967 25736.18863548228 26028.156893471878 24139.283745542587 17318.587569005227 16334.00893423533 18360.74213103602 20892.802734511162 16037.132847985808 17624.87789334499 1.1124990831599837 1.4602194007369578 1.4767850904260673 1.3696142402585032 0.9826217051719027 0.9267587005753338 1.0417514516777948 1.185415459950512 0.9099145506160526 1.0 14.105325641981398 -6.258118926658005 24.63053887566788 1.0146655533385112 1.3710255905261632 0.6793212809764075 0.1165375525088059 140.1099249170866 1039308.7011709092 0.035546007154891236 0.04398383271226639 5.519262797825552e-07 6.258118926658005 0.3563600371876521 EYAENIGDGRS(ph)PEFR ddPTM_PC-9_Lapatinib_30min_R1 2 EYAENIGDGRSPEFR 15 1 A0A087WUB9;Q8WYA6-3;Q8WYA6-2;Q8WYA6-4;Q8WYA6 A0A087WUB9 CTNNBL1 Beta-catenin-like protein 1 1 EYAENIGDGRS(1)PEFR;EY(0.001)AENIGDGRS(0.999)PEFR 92.26899999999999 0.0017194000000000003 13130600.0 35153.0 46600.0 54468.0 45540.0 58936.0 54645.0 52546.0 61212.0 47287.0 45702.0 True False 34651.71177372932 46492.10056309547 49989.851292560255 48889.16351698657 55469.50035263418 52307.96073371663 55266.57477044741 64056.132985392396 41961.040105814725 53601.52980591287 0.6464687089939518 0.8673651802745161 0.9326198612907088 0.9120852276793325 1.0348492021307059 0.9758669374385366 1.0310633851414979 1.1950430000288212 0.7828328829000313 1.0 15.709986555827811 -4.154511648619893 0.7776036835945984 1.009906219217681 6.268593527668683e-18 0.5355815810262681 0.09737008522237682 4.61346485096879 1.0654866331614106 0.03504936304938082 5.077920699046682 7.006293903749531e-05 4.154511648619893 -1.009906219217681 EYCLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 EYCLSPR 7 0 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3 C9JWC4 HJURP Holliday junction recognition protein 1 EYCLS(1)PR;EYCLS(1)PR;EYCLS(1)PR 85.86200000000001 0.019 58588400.0 116501.0 101484.0 153570.0 200081.0 165126.0 163773.0 130478.0 164116.0 132110.0 142080.0 True False 153545.8946286634 134286.7183722158 151533.5614591447 153955.4166706351 142201.10518223554 153532.24842027627 142090.28923062145 138755.64321050324 139093.06489208966 137105.82244578615 1.1199079068241462 0.9794384802681515 1.1052306806230896 1.1228948116445716 1.0371631389940725 1.119808376343648 1.0363548877496158 1.012033192575534 1.0144942235920673 1.0 17.064930313499232 -7.4923731203632675 5.9716362244635 1.0122450872748683 1.0774316732057914 0.37295746979223154 0.04222365579512693 0.21358049389902056 24.073023172811926 0.018347588930194975 0.011733391538769983 3.218302626210151e-08 7.4923731203632675 0.06518658593092308 EYCLS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EYCLSPR 7 0 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3 C9JWC4 HJURP Holliday junction recognition protein 1 EYCLS(1)PR;EYCLS(1)PR;EYCLS(1)PR;EY(0.001)CLS(0.999)PR 85.161 0.019469999999999998 81246000.0 164744.0 167633.0 210908.0 201595.0 241875.0 203986.0 222024.0 199401.0 203543.0 146405.0 True False 192631.9053576817 184274.49639209767 215936.84659304458 190300.28572980824 194481.33006421526 193288.61506317012 200992.27940544026 194166.93503282344 206519.43130947585 172947.06755865767 1.1138200148571333 1.0654965070720157 1.248571887579454 1.1003383197883072 1.124513602974239 1.1176171865279723 1.1621606670912221 1.1226957344446948 1.1941193003427573 1.0 17.3999710264278 -10.866342885589116 4.974867682576321 0.9999252830398023 1.137923340220802 0.4188592963062897 0.04904266112622478 3.928598797334548e-05 5.18460766173686e-06 0.04589669266324848 0.011125563727917336 1.3603702144554116e-11 10.866342885589116 0.13799805718099967 EYCLS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 EYCLSPR 7 0 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3 C9JWC4 HJURP Holliday junction recognition protein 1 EYCLS(1)PR 83.948 0.020284 37677000.0 50547.0 49148.0 59149.0 49245.0 53430.0 51559.0 51439.0 41196.0 59633.0 48112.0 True False 49826.1905108155 49034.20082564414 54285.99754174279 52866.64157650427 50287.35244742167 49353.94175989931 54102.259727039964 43110.11655339189 52916.503576671144 56428.09509478975 0.8830032349508846 0.868967856229683 0.9620384570939602 0.9368851010777018 0.8911757939541879 0.874634199098746 0.9587823164357617 0.7639831981032518 0.9377687389195095 1.0 15.784126027311997 EYEEEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EYEEEER 7 0 Q16543;K7EKQ2;K7EL68;K7EQA9;K7EIU0 Q16543 CDC37 Hsp90 co-chaperone Cdc37;Hsp90 co-chaperone Cdc37, N-terminally processed 0 ; 116.9 0.034976 7098400.0 27932.0 39850.0 34742.0 34348.0 33956.0 29108.0 34770.0 24885.0 24460.0 21646.0 False True 32660.335917852983 43806.04464052491 35570.38103976873 32423.592917718484 27302.56555518554 27581.525238294565 31476.333886999397 24231.795117836973 24817.681226226297 25570.24845035828 1.277278786761079 1.7131646071241486 1.3910846861274957 1.2680202533293798 1.06774737086307 1.078656912225196 1.2309748944405883 0.947655833883673 0.9705686385647365 1.0 14.642178557976427 -5.950157286122262 1.8245309716557256 1.0525809346127142 1.503065625676152 0.6925148251791406 0.12394831833002827 0.18983983308734276 1.279541550260475 0.03986604220956666 0.06798724777261775 1.121612172421911e-06 5.950157286122262 0.4504846910634379 EYEEEER ddPTM_PC-9_Lapatinib_30min_R1 1 EYEEEER 7 0 Q16543;K7EKQ2;K7EL68;K7EQA9;K7EIU0 Q16543 CDC37 Hsp90 co-chaperone Cdc37;Hsp90 co-chaperone Cdc37, N-terminally processed 0 109.86 0.044001 2470000.0 9921.2 11652.0 13747.0 14422.0 12836.0 13219.0 13983.0 13687.0 14782.0 10029.0 False True 9779.72186867475 11625.02050989674 12616.77472495458 15482.641990381653 12081.01171654696 12653.654184994053 14706.97132065554 14322.947986850057 13117.095498639228 11762.499287197496 0.8314323027691203 0.9883121117422392 1.0726270341786028 1.3162714498298185 1.0270786353794843 1.0757623763485797 1.250327074337242 1.2176789674656472 1.1151622778771257 1.0 13.521907015076552 -5.018048882316444 1.8845048810314515 1.1497600359739535 0.8095171738045075 0.5079694332664753 0.09504491532851955 0.4027732329442445 2.1310460231257866 0.026392489338445988 0.2056023358857039 9.592926515898309e-06 5.018048882316444 -0.340242862169446 EYFT(ph)FPASK ddPTM_PC-9_AZD4547_30min_R2 2 EYFTFPASK 9 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 EYFT(0.989)FPAS(0.011)K;EY(0.001)FT(0.998)FPAS(0.002)K 103.43 0.0069867 17150800.0 69741.0 57989.0 113874.0 137437.0 122142.0 103823.0 130057.0 129926.0 109809.0 121737.0 True False 91917.18729708438 76732.81021329884 112363.9563560501 105753.02303048309 105184.69162438765 97330.93139735084 141631.8210462064 109848.92210246269 115613.27956048338 117475.0246838591 0.7824402467200645 0.6531840314126091 0.9564922983284015 0.9002170743532809 0.8953791830004176 0.8285244600652889 1.2056334648778024 0.9350832008597635 0.9841519920648162 1.0 16.84199454531504 -5.2137461077102065 0.5048481572065643 1.012951292265731 0.5919172401713849 0.4512728865272172 0.10285464578250708 2.773113817891826 0.7435550205820479 0.07001790895747878 0.658152444820802 6.112992912887998e-06 5.2137461077102065 -0.4210340520943462 EYFT(ph)FPASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EYFTFPASK 9 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 EYFT(0.993)FPAS(0.007)K;EYFT(0.92)FPAS(0.08)K;EYFT(1)FPASK 99.522 0.010059 17953700.0 47454.0 55556.0 65904.0 85888.0 73620.0 77356.0 60266.0 65422.0 61179.0 48175.0 True False 55487.024940777424 61071.23252318694 67475.40130231179 81075.97381265297 59194.68948559194 73299.31518254474 54557.16819194441 63704.74182033874 62073.62713570313 56908.7461469098 0.9750175271396385 1.0731431749617484 1.185677173911444 1.4246663176053032 1.0401685767734363 1.28801493874637 0.9586780923112451 1.1194191777813045 1.0907572445096612 1.0 15.796362772909243 -7.26976849756674 24.967920205302406 1.0521652368603622 1.167441745118974 0.1806258349063441 0.12673838216844516 1237.041181470478 3708220.6595817115 0.053934557229657225 0.03709461559257794 5.3731813965670656e-08 7.26976849756674 0.1152765082586118 EYFT(ph)FPASK ddPTM_PC-9_Lapatinib_30min_R1 2 EYFTFPASK 9 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 EYFT(0.969)FPAS(0.031)K;EYFT(0.515)FPAS(0.485)K 122.69 0.0037681 21732000.0 88623.0 63536.0 85114.0 77237.0 51756.0 49679.0 36977.0 37968.0 53320.0 38174.0 True False 87359.2197685323 63388.88629564022 78116.25546954118 82917.26663507872 48711.81383621105 47554.34497740523 38891.48813014945 39732.13188899854 47314.54011550831 44772.32503634236 1.9511879201632154 1.4158051038043373 1.7447442232703587 1.8519758928707308 1.0879893728250867 1.062137044229994 0.8686501783988358 0.8874261467714125 1.0567809484341588 1.0 15.45031961919596 -6.347036312628963 4.587024316115795 0.973444699846538 1.7173900077935502 0.8682134648039057 0.1427546797163667 0.07828235125037086 2.9171039606860423 0.04541535433255152 0.052071376207606046 4.497422490592896e-07 6.347036312628963 0.7439453079470122 EYGS(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 4 EYGSPLK 7 0 P21127;P21127-8;A0A0D9SEN2;A0A0D9SER5;A0A0D9SEI3;P21127-9;P21127-2;P21127-3;P21127-6;P21127-10;P21127-5;P21127-4;P21127-12;Q5QPR4;Q5QPR3;Q9UQ88-4;Q9UQ88-3;Q9UQ88-2;Q9UQ88;Q9UQ88-5;Q9UQ88-10 P21127;Q5QPR4 CDK11B;CDK11A Cyclin-dependent kinase 11B;Cyclin-dependent kinase 11A 1 EY(0.001)GS(0.999)PLK;EYGS(1)PLK;EY(0.01)GS(0.99)PLK;EYGS(1)PLK 80.755 0.024942 259047000.0 420115.0 535142.0 481859.0 422932.0 406840.0 564114.0 525728.0 568910.0 596865.0 481695.0 True False 553702.8310651492 708116.1862278222 475469.23481892305 325431.5616342629 350357.2885695818 528839.8624031789 572516.7735299137 480998.0317512441 628414.0653759519 464831.0046665477 1.1911916922632018 1.5233841527756913 1.022886231868304 0.7001072612781397 0.7537304634421169 1.1377035031958525 1.231666493375621 1.0347804404663024 1.3519194267747965 1.0 18.826346775508995 -5.282074173550949 23.189199064162082 1.0198702782507854 1.3572878623229456 0.30139025677599085 0.19946927331130446 354.76551830836405 398682.45211401413 0.05664757184801288 0.11821256033934133 5.223069760957977e-06 5.282074173550949 0.33741758407216027 EYGS(ph)PLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EYGSPLK 7 0 P21127;P21127-8;A0A0D9SEN2;A0A0D9SER5;A0A0D9SEI3;P21127-9;P21127-2;P21127-3;P21127-6;P21127-10;P21127-5;P21127-4;P21127-12;Q5QPR4;Q5QPR3;Q9UQ88-4;Q9UQ88-3;Q9UQ88-2;Q9UQ88;Q9UQ88-5;Q9UQ88-10 P21127;Q5QPR4 CDK11B;CDK11A Cyclin-dependent kinase 11B;Cyclin-dependent kinase 11A 1 EY(0.002)GS(0.998)PLK;EYGS(1)PLK 73.985 0.034872 70171000.0 192622.0 235440.0 185480.0 193036.0 207653.0 138839.0 192341.0 150275.0 136262.0 151710.0 True False 225229.1001420834 258812.92723124626 189902.54663681742 182220.81875115618 166964.885299533 131558.03842790905 174121.06805175007 146330.44047952368 138254.57396762236 179213.82206430062 1.2567618811303116 1.4441571763275383 1.059642300183084 1.0167788212550741 0.9316518300671429 0.7340842180169952 0.9715828056458541 0.8165131394107614 0.7714503958183405 1.0 17.4513223855746 -5.617146853803302 1.3918690588970892 0.8598135327867236 1.3683090196117533 0.7678566700925543 0.09980998589469256 0.2008209235106996 0.7478424670550503 0.031232306047014963 0.09213347765052007 2.4146442004356248e-06 5.617146853803302 0.5084954868250298 EYGS(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 2 EYGSPLK 7 0 P21127;P21127-8;A0A0D9SEN2;A0A0D9SER5;A0A0D9SEI3;P21127-9;P21127-2;P21127-3;P21127-6;P21127-10;P21127-5;P21127-4;P21127-12;Q5QPR4;Q5QPR3;Q9UQ88-4;Q9UQ88-3;Q9UQ88-2;Q9UQ88;Q9UQ88-5;Q9UQ88-10 P21127;Q5QPR4 CDK11B;CDK11A Cyclin-dependent kinase 11B;Cyclin-dependent kinase 11A 1 EYGS(1)PLK;EYGS(1)PLK 85.676 0.019124000000000002 190363000.0 283456.0 426078.0 319400.0 309465.0 459302.0 396170.0 427968.0 409026.0 388077.0 316426.0 True False 279413.86546053557 425091.44256915426 293140.1649196543 332224.0884449775 432286.7593824752 379226.7326173758 450126.08897649316 428030.8411828252 344367.6816280219 371119.81248885876 0.7528939605425236 1.1454291262930505 0.7898801278049647 0.8951936201329889 1.1648172499425713 1.021844482174501 1.212886172683131 1.1533494757725309 0.9279151099979606 1.0 18.50152549680461 -6.248999760123741 24.44167977831447 1.0915258796003344 0.9061071062429749 0.33656852707433116 0.12581740391188073 659.3024736061752 1295412.9122134917 0.03594084889461997 0.04604300305224012 5.636379671431255e-07 6.248999760123741 -0.18541877335735957 EYGS(ph)TSSIDK ddPTM_PC-9_AZD4547_30min_R2 2 EYGSTSSIDK 10 0 O43166-3;O43166-2;O43166 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 EYGS(0.491)T(0.491)S(0.018)S(0.001)IDK;EYGS(0.491)T(0.491)S(0.017)S(0.001)IDK 187.31 0.00079502 64808000.0 137771.0 171001.0 175473.0 173263.0 166300.0 180269.0 176417.0 196351.0 181959.0 167534.0 True False 181579.31218517938 226273.72914318767 173146.1133679784 133319.89223666544 143212.11554695072 168996.75093253967 192117.77123498623 166009.46464711204 191576.9812633392 161668.68565338108 1.1231569765742195 1.3996138351017482 1.0709935116266425 0.8246488285462055 0.885837074558759 1.045327672761997 1.1883425071376421 1.0268498440263047 1.1849974563044432 1.0 17.30268073811191 -5.437526009080741 7.243737128977817 1.0198277990417377 1.2581712059237569 0.37012062922493527 0.12293561403033493 0.2843599844998805 20.968105363660328 0.03419458479979634 0.07149757189904067 3.651522583171523e-06 5.437526009080741 0.23834340688201916 EYGS(ph)TSSIDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EYGSTSSIDK 10 0 O43166-3;O43166-2;O43166 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 EYGS(0.489)T(0.489)S(0.023)SIDK;EYGS(0.491)T(0.491)S(0.017)S(0.001)IDK 187.31 0.00040998 45361000.0 177094.0 240000.0 175661.0 170562.0 181331.0 120271.0 167206.0 127673.0 122185.0 114825.0 True False 207072.51643406323 263825.6138952567 179849.42443805197 161005.96410946478 145800.49224547533 113963.7770350049 151367.0372133912 124321.71903072562 123971.72447369031 135641.86354579986 1.5266121462873046 1.9450161402875097 1.3259138420589842 1.1869931590485754 1.0748930192649955 0.8401814458743757 1.1159315660852867 0.9165438735567655 0.9139635893592019 1.0 17.049442984834464 -5.655412576629882 1.6470909650258834 0.9753336011446124 1.7457943123910393 0.8236683740541622 0.1347494346648024 0.13964397145689625 0.7553738887147029 0.03994269549978951 0.09885477479845799 2.2109932838986066e-06 5.655412576629882 0.7704607112464269 EYGS(ph)TSSIDK ddPTM_PC-9_Lapatinib_30min_R1 2 EYGSTSSIDK 10 0 O43166-3;O43166-2;O43166 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 EYGS(0.446)T(0.446)S(0.062)S(0.045)IDK;EYGS(0.449)T(0.449)S(0.019)S(0.083)IDK 199.8 0.00049071 76100000.0 192808.0 333800.0 282410.0 264540.0 300160.0 271660.0 276020.0 285220.0 265490.0 260040.0 True False 190058.522563343 333027.1066086106 259191.3399341259 283995.1540795706 282505.17893726507 260041.7350703902 290310.96502376784 298472.36244680214 235587.7204663598 304987.5675184801 0.6231680986531583 1.091936662593407 0.8498423133868258 0.9311696092738682 0.9262842457345322 0.8526306078185744 0.9518780302616008 0.978637801125178 0.7724502424253239 1.0 18.218390908440185 -1.5231228964026513 0.014923899605805174 1.6570399870230126 1.5747235158225073e-06 0.07370334054782435 0.11982064725365836 19421.21020561054 22.463174579734133 998.6284972094543 1551.7369809181662 0.02998313937774538 1.5231228964026513 -1.6570384122994968 EYGST(ph)SSIDK ddPTM_PC-9_Lapatinib_30min_R1 1 EYGSTSSIDK 10 0 O43166-3;O43166-2;O43166 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 EYGS(0.146)T(0.831)S(0.022)S(0.001)IDK 174.77 0.0040765 39990000.0 96231.0 172280.0 168960.0 121920.0 182450.0 171540.0 167620.0 153810.0 144090.0 136450.0 True False 94858.72829339597 171881.09624485133 155068.76100446077 130886.40351319735 171718.64971050122 164203.63407927065 176298.543429041 160956.57411101126 127861.06686503346 160035.2006918036 0.5927366472084805 1.0740205623627805 0.9689665794408119 0.8178600892016181 1.0730054948423358 1.0260469782238386 1.1016235344907488 1.0057573172353629 0.7989558941552415 1.0 17.288029743786858 -4.753670181646158 24.99856288484091 0.9872490456825561 0.5927359374846599 0.5946014219533264 0.09718880416458507 203.35483845481608 654271.9031524374 0.02464492058760737 0.2592803789587954 1.76331466061279e-05 4.753670181646158 -0.3945131081978962 EYGSTS(ph)SIDK ddPTM_PC-9_AZD4547_30min_R2 1 EYGSTSSIDK 10 0 O43166-3;O43166-2;O43166 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 EYGS(0.119)T(0.268)S(0.408)S(0.205)IDK 97.45200000000001 0.0051398 37517000.0 14181.0 13274.0 21100.0 20877.0 21850.0 20108.0 23000.0 19655.0 24413.0 20105.0 True False 18690.263016876077 17564.56091278222 20820.200213504904 16064.130196434691 18816.50465845385 18850.643581267486 25046.95544309606 16617.771376967732 25703.421339872708 19401.130069485724 0.9633595027679493 0.9053370009826347 1.073143684874888 0.8279997164546875 0.969866424845459 0.9716260606342696 1.2910049751426667 0.8565362593545165 1.3248414524213352 1.0 14.243853067949487 -7.031552424646981 24.509713084543094 1.1097368465845288 0.9483545517791174 0.26138403525144704 0.13706818441986857 724.3508109623909 562668.6787287728 0.04812672918764078 0.03732243227449122 9.299242547659963e-08 7.031552424646981 -0.16138229480541133 EYGSTS(ph)SIDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EYGSTSSIDK 10 0 O43166-3;O43166-2;O43166 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 EYGS(0.103)T(0.317)S(0.569)S(0.011)IDK 176.95 0.0016357 43506000.0 134220.0 171200.0 129840.0 121620.0 139940.0 134430.0 121110.0 98228.0 118200.0 82281.0 True False 156940.7950341623 188195.60457861633 132935.87802094224 114806.02569735989 112519.76156769533 127380.25414950993 109637.58403953108 95649.61908116899 119928.45138756973 97197.8939639624 1.614652217591777 1.9362107233351447 1.3676826996913147 1.181157543803634 1.1576357982551941 1.3105248370580755 1.1279831235868225 0.9840709009254104 1.233858538457994 1.0 16.568637434114414 -5.470400628358984 3.389283186703068 1.1510632023370042 1.7727371907944098 0.8148047637343676 0.11909587871356739 0.09213045706565738 2.097548340542709 0.032071895658628106 0.07048791674053552 3.3853172301036633e-06 5.470400628358984 0.6216739884574056 EYIPGQPPLS(ph)QSS(ph)DSSPTR ddPTM_PC-9_AZD4547_30min_R2 1 EYIPGQPPLSQSSDSSPTR 19 0 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 2 EYIPGQPPLS(0.564)QS(0.331)S(0.447)DS(0.438)S(0.183)PT(0.037)R 94.68799999999999 0.0090861 5180500.0 26282.0 29510.0 37220.0 39841.0 36982.0 35161.0 33457.0 46582.0 34942.0 35853.0 True False 34639.129300439825 39048.5304004975 36726.43848088404 30656.272987313994 31847.687655786736 32962.37711164445 36434.60818520285 39383.822247871314 36788.9627844932 34597.79738280389 1.0011946401436664 1.1286420915311144 1.0615253356890906 0.8860758576079486 0.920511999749902 0.9527305090244764 1.0530903971162022 1.1383332242834112 1.0633325115308752 1.0 15.078392573305797 -10.326504089428342 9.682657288655603 0.9999999999999418 1.0222711504421238 0.007328170837697101 0.07946454374552683 0.0 0.0 0.08703356587866075 0.02110874014224948 4.715154314051855e-11 10.326504089428342 0.022271150442181975 EYIPGQPPLSQS(ph)S(ph)DSSPTR ddPTM_PC-9_Lapatinib_30min_R1 1 EYIPGQPPLSQSSDSSPTR 19 0 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 2 EYIPGQPPLS(0.225)QS(0.774)S(0.514)DS(0.221)S(0.251)PT(0.014)R 198.98 5.996699999999999e-14 5692000.0 58261.0 82376.0 89105.0 75002.0 89612.0 87986.0 78745.0 83668.0 91850.0 74718.0 True False 57430.18745624112 82185.26343316628 81779.13085524688 80517.89727933757 84341.19834397068 84223.04388538362 82822.0307977559 87555.52072505077 81504.88577662104 87632.90674452313 0.655349566615059 0.9378356428682846 0.9332011671558287 0.9188089300069893 0.9624375303429248 0.9610892416352191 0.9451019471396468 0.9991169296746258 0.9300716911540187 1.0 16.419185092783913 -4.759498195687948 5.064708598204252 0.9537645395255185 0.6363792035017803 0.9242503972861982 0.02570517077560287 0.04231321184196652 2.9168583886535884 0.006361229301241055 0.0479238031299471 1.7398099262063336e-05 4.759498195687948 -0.3173853360237382 EYIPGQPPLSQS(ph)SDS(ph)SPTR ddPTM_PC-9_AZD4547_30min_R2 1 EYIPGQPPLSQSSDSSPTR 19 0 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 2 EYIPGQPPLS(0.038)QS(0.945)S(0.019)DS(0.71)S(0.269)PT(0.021)R 149.95 5.5375e-14 0.0 13202.0 14323.0 12858.0 17823.0 16522.0 18197.0 14593.0 19269.0 16341.0 14209.0 True False 17399.961381341098 18952.629648469185 12687.49451873205 13714.182712605048 14228.205490479382 17059.138713364053 15891.748729613077 16291.41880757014 17204.75189918732 13711.547234882997 1.2690005790939884 1.382238585026536 0.9253145762029178 1.0001922086309374 1.0376805218802716 1.2441439628318955 1.1590047758566238 1.1881532060892293 1.2547637115246484 1.0 13.743103756074762 -6.772051733946484 24.979410552572165 1.1803346592766886 1.1195013668089997 0.023763843212245894 0.13880443489616467 901.478927953861 2121894.6146556307 0.05252776178038741 0.04680224970676196 1.6902395752462745e-07 6.772051733946484 -0.06083329246768887 EYIPGQPPLSQS(ph)SDS(ph)SPTR ddPTM_PC-9_Lapatinib_30min_R1 1 EYIPGQPPLSQSSDSSPTR 19 0 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 2 EYIPGQPPLS(0.07)QS(0.917)S(0.03)DS(0.571)S(0.396)PT(0.016)R 166.34 1.0288e-06 5029900.0 50342.0 75956.0 75280.0 62727.0 71288.0 67128.0 74903.0 70566.0 72934.0 58990.0 True False 49624.113848407884 75780.12854872289 69090.76898920335 67340.15283113786 67094.97999760046 64257.091923010834 78781.11083680629 73844.7539738484 64719.40489093179 69186.34290076594 0.7172530266498377 1.0953047288164142 0.9986186014818029 0.9733156864169555 0.9697720270290174 0.928753988560645 1.1386800853139778 1.067331367402437 0.9354361305634974 1.0 16.078199663453958 -7.220791166183696 24.989524401272938 1.0409730016424363 0.9584575053446617 0.14741774783038097 0.10139478814226516 1044.5687229298044 642175.7344474142 0.03776414533936009 0.029251554527267947 6.014628859773642e-08 7.220791166183696 -0.08251549629777466 EYIPGQPPLSQS(ph)SDSS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 1 EYIPGQPPLSQSSDSSPTR 19 0 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 2 EYIPGQPPLS(0.432)QS(0.56)S(0.008)DS(0.295)S(0.652)PT(0.053)R 154.72 0.00023819 4716100.0 17515.0 20504.0 23681.0 26165.0 24646.0 28453.0 23830.0 34087.0 26430.0 24526.0 True False 23084.40566536805 27131.517022426317 23366.974467109474 20133.063495220274 21224.328320926943 26673.829412065035 25950.82383517303 28819.637391335495 27827.035842085592 23667.352205133408 0.975369169533087 1.1463689215112765 0.9873083505319711 0.8506681829348637 0.8967766287064179 1.127030568560159 1.0964819220269322 1.2176958850971324 1.1757561894080384 1.0 14.530610692542332 -6.81483518814017 10.181850391272883 1.1356022544661044 0.9752772183705429 0.4177973112965686 0.0891325716259354 0.4655426230003136 85.78195341656594 0.03402577325185517 0.03004576646521535 1.5316686094276983e-07 6.81483518814017 -0.16032503609556148 EYIPGQPPLSQS(ph)SDSSPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EYIPGQPPLSQSSDSSPTR 19 0 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 EYIPGQPPLS(0.064)QS(0.234)S(0.19)DS(0.234)S(0.234)PT(0.044)R 50.425 0.033473 6772200.0 14526.0 19784.0 17119.0 18410.0 20726.0 16723.0 19470.0 14550.0 17379.0 16286.0 True False 16984.964898422328 21748.024772098972 17527.181884169044 17378.54738602531 16664.88908283589 15846.016440841015 17625.660649406913 14168.077916999313 17633.134997162182 19238.522880094926 0.8828622137095444 1.1304415057041877 0.9110461335003782 0.9033202545922051 0.8662249792616958 0.8236607633341769 0.9161649654321041 0.7364431253533642 0.9165534748723483 1.0 14.231710413825317 -5.492581450019959 12.900528058254709 0.8709111186909652 1.010202268994183 0.2491741875198097 0.08535491565983475 2.2249940072445984 944.4391877791196 0.020939498052989704 0.04287975157078649 3.2167591870824342e-06 5.492581450019959 0.13929115030321781 EYIPGQPPLSQS(ph)SDSSPTR ddPTM_PC-9_Lapatinib_30min_R1 1 EYIPGQPPLSQSSDSSPTR 19 0 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 EYIPGQPPLS(0.004)QS(0.227)S(0.227)DS(0.227)S(0.227)PT(0.086)R 79.455 0.0015772 2937600.0 17777.0 27889.0 26850.0 21057.0 23584.0 26962.0 25762.0 24908.0 30350.0 23009.0 True False 17523.49672009747 27824.42473399504 24642.496643997263 22605.6020240928 22196.835487927998 25808.89811149179 27095.830305565894 26065.316611124526 26931.663400331516 26986.07499243467 0.6493532951720487 1.0310660124451367 0.913156012903158 0.8376765435666395 0.8225292301363093 0.956378358791603 1.0040671091724895 0.9658802407697944 0.9979837159676459 1.0 14.719927537875908 -6.904203405222921 5.205526565176718 0.9880148013952681 0.8639725650345359 0.3598719325767844 0.08939402725612569 0.264622394050792 11.533288177774645 0.03149333799465499 0.02768112741703668 1.2467994291929585e-07 6.904203405222921 -0.1240422363607322 EYIPGQPPLSQSS(ph)DSSPTR ddPTM_PC-9_AZD4547_30min_R2 2 EYIPGQPPLSQSSDSSPTR 19 0 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 EYIPGQPPLS(0.001)QS(0.015)S(0.857)DS(0.112)S(0.014)PT(0.002)R;EYIPGQPPLS(0.004)QS(0.139)S(0.459)DS(0.197)S(0.197)PT(0.004)R 192.22 8.2321e-12 50125400.0 228171.0 335570.0 325577.0 354500.0 322850.0 335697.0 274460.0 364970.0 277196.0 313181.0 True False 300724.631748369 444036.4400709905 321259.63625176763 272775.5019704023 278027.8502966507 314705.8135220181 298886.40830052824 308572.2726762605 291848.0146531498 302216.62851487775 0.9950631546191202 1.4692654148549973 1.063011118317576 0.9025827047004262 0.9199621200954657 1.041325274087377 0.9889806850446498 1.0210300941831527 0.9656914514840552 1.0 18.205223516858666 -5.509485869056348 24.306671875989924 0.9790618639619477 1.2406578254682332 0.44249965901363153 0.11325795109930355 330.0164469021839 598943.8277807578 0.027763750550593012 0.053957059235614495 3.0939559840261284e-06 5.509485869056348 0.2615959615062855 EYIPGQPPLSQSS(ph)DSSPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EYIPGQPPLSQSSDSSPTR 19 0 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 EYIPGQPPLS(0.003)QS(0.081)S(0.668)DS(0.172)S(0.075)PT(0.001)R;EYIPGQPPLS(0.015)QS(0.244)S(0.516)DS(0.103)S(0.087)PT(0.036)R;EYIPGQPPLSQS(0.001)S(0.628)DS(0.259)S(0.11)PT(0.002)R;EYIPGQPPLSQS(0.049)S(0.895)DS(0.034)S(0.015)PT(0.007)R 206.45 1.8222e-20 912568300.0 467879.0 530115.0 539507.0 524345.0 576645.0 475358.0 540412.0 436930.0 414857.0 366295.0 True False 547081.673668522 582741.3137920165 552370.8929716916 494967.6495994264 463655.551730768 450429.38966006745 489220.2631159361 425461.05046560115 420923.49879266473 432701.3839103757 1.2643400137167984 1.3467516755451796 1.2765637308109528 1.1439012399875934 1.0715370206137445 1.040970531662001 1.1306186698429117 0.9832671359186727 0.9727805697978759 1.0 18.723012209380677 -5.961158092575348 1.477955386323465 1.029819889465225 1.3162551902270374 0.869549057763865 0.045788144004092354 0.1414755639957996 0.6268529681596252 0.016641517461107525 0.030445624854237352 1.0935582149895499e-06 5.961158092575348 0.28643530076181234 EYIPGQPPLSQSS(ph)DSSPTR ddPTM_PC-9_Lapatinib_30min_R1 2 EYIPGQPPLSQSSDSSPTR 19 0 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 EYIPGQPPLSQS(0.001)S(0.615)DS(0.265)S(0.117)PT(0.001)R;EYIPGQPPLSQS(0.001)S(0.665)DS(0.229)S(0.081)PT(0.024)R 248.01 7.1773e-54 1905590000.0 400170.0 487970.0 540080.0 456660.0 555210.0 522250.0 483950.0 481310.0 551660.0 406300.0 True False 394463.50241780933 486840.13544578623 495676.70716908784 490244.2997731028 522553.63938485883 499914.58492421167 509006.5630144644 503673.4197085408 489526.2415626653 476528.41363928036 0.8277859013804956 1.0216392590900394 1.0401828998685947 1.0287829345349488 1.0965844311235937 1.049076131906447 1.0681557456923632 1.0569640871190704 1.027276081659265 1.0 18.862202713743805 -4.736207794064792 3.1392663531707985 1.0495692084984178 0.7797200150507883 0.8732466183486152 0.024731589101057484 0.13593198477710103 1.812746429599854 0.006177792996978434 0.09680340348098145 1.8356598369387064e-05 4.736207794064792 -0.2698491934476296 EYIPGQPPLSQSSDS(ph)SPTR ddPTM_PC-9_AZD4547_30min_R2 3 EYIPGQPPLSQSSDSSPTR 19 0 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 EYIPGQPPLSQS(0.007)S(0.025)DS(0.639)S(0.302)PT(0.027)R;EYIPGQPPLS(0.015)QS(0.01)S(0.01)DS(0.575)S(0.366)PT(0.025)R;EYIPGQPPLSQSS(0.129)DS(0.435)S(0.435)PT(0.001)R 214.46 1.1459000000000001e-27 74969700.0 88718.2 88521.0 108684.0 123484.0 115342.0 107100.0 101102.0 124719.0 104168.0 97215.9 True False 116928.74214680327 117133.68212749717 107242.77914713592 95016.67160878186 99328.75424784356 100403.0200693132 110099.882139474 105446.54430750659 109674.1078168133 93812.40093121718 1.2464102931608678 1.2485948655485222 1.1431620775356324 1.0128370094530215 1.0588019628734473 1.0702531762610812 1.1736175713080697 1.1240149837420694 1.1690789994515314 1.0 16.517491022753212 -5.37405118800247 3.7134344726520796 1.0930276021556906 1.2482685116710575 0.5666479996503926 0.05517024516552277 0.17823014893292854 4.36742734815465 0.015607599228960873 0.03601354297117852 4.2261879947866045e-06 5.37405118800247 0.15524090951536684 EYIPGQPPLSQSSDS(ph)SPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 EYIPGQPPLSQSSDSSPTR 19 0 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 EYIPGQPPLSQSS(0.004)DS(0.675)S(0.29)PT(0.03)R;EYIPGQPPLSQS(0.005)S(0.035)DS(0.466)S(0.466)PT(0.028)R;EYIPGQPPLSQS(0.001)S(0.002)DS(0.473)S(0.262)PT(0.262)R;EYIPGQPPLSQS(0.002)S(0.028)DS(0.664)S(0.293)PT(0.013)R 232.51 3.979999999999999e-102 251170100.0 186217.0 299098.0 235519.0 246857.0 252044.0 201853.0 245254.0 170820.0 187122.0 180274.0 True False 217739.86014660017 328790.4727701803 241134.6661707809 233026.4026111925 202657.7875129929 191267.4733381019 222021.76563480435 166336.15599875094 189858.3052499556 212956.24915180076 1.022462881525442 1.543934371870956 1.1323202166229638 1.0942454308776128 0.9516404816490411 0.8981538419272282 1.0425698542264494 0.7810813566695674 0.8915366701195965 1.0 17.700197540498017 -5.917662734068249 1.6787665290793266 0.9172062880813152 1.28412722710829 0.5035624286914601 0.13809844397103332 0.27085251714337205 1.5514681910331767 0.043470083969200234 0.07880477689576773 1.2087521677100933e-06 5.917662734068249 0.36692093902697476 EYIPGQPPLSQSSDS(ph)SPTR ddPTM_PC-9_Lapatinib_30min_R1 2 EYIPGQPPLSQSSDSSPTR 19 0 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 EYIPGQPPLSQS(0.002)S(0.042)DS(0.609)S(0.322)PT(0.025)R;EYIPGQPPLSQS(0.005)S(0.059)DS(0.675)S(0.259)PT(0.001)R 240.82 3.9260999999999994e-44 156819000.0 39619.0 57180.0 59140.0 51468.0 61305.0 63195.0 56507.0 52683.0 61072.0 42940.0 True False 39054.02579476524 57047.60322312874 54277.737487001774 55253.12841221487 57699.16043026733 60492.29716474012 59432.65596912552 55130.84450874712 54193.42824332939 50362.121786046504 0.7754642657963963 1.132748208375417 1.0777492202888113 1.097116770555197 1.14568565390058 1.2011467154169886 1.1801062755380598 1.0946886777916067 1.0760751596916316 1.0 15.620051445484128 -4.760062773636588 24.999985049726376 1.1191388738604342 0.7754638489297698 0.7703954622971627 0.05493333080768763 16.2676217248967 295322.16090226325 0.013957322851032076 0.08493196697950718 1.737549662320312e-05 4.760062773636588 -0.3436750249306644 EYIPGQPPLSQSSDS(ph)SPTRNSEPAGLETPEAK ddPTM_PC-9_AZD4547_30min_R2 1 EYIPGQPPLSQSSDSSPTRNSEPAGLETPEAK 32 1 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 EY(0.001)IPGQPPLS(0.01)QS(0.032)S(0.032)DS(0.231)S(0.231)PT(0.231)RNS(0.231)EPAGLET(0.002)PEAK 49.707 0.0039664999999999995 7632400.0 34667.0 13813.0 37725.0 106310.0 79310.0 32736.0 26593.0 37835.0 26663.0 45095.0 True False 45690.38488160515 18277.78212206274 37224.74185092288 81801.87197312686 68299.17549025042 30689.01274499566 28959.72548253278 31988.47011180738 28072.351746406675 43516.23777584976 1.0499617434060895 0.4200221125780863 0.8554218782116666 1.8798011076804189 1.5695101180864137 0.7052312955700221 0.665492399221253 0.7350927319723408 0.6451006148786605 1.0 15.409266212407303 -6.856024214786586 24.999931678241477 0.7283220847217071 1.1378813327282034 0.22163878885020194 0.3774717851036623 28.704738288148263 7569.752531146122 0.15113525337073086 0.13328880059753886 1.393079127414958e-07 6.856024214786586 0.40955924800649623 EYIPGQPPLSQSSDSS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 4 EYIPGQPPLSQSSDSSPTR 19 0 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 EYIPGQPPLSQS(0.003)S(0.014)DS(0.287)S(0.692)PT(0.004)R;EYIPGQPPLSQSSDS(0.404)S(0.588)PT(0.008)R;EYIPGQPPLSQS(0.002)S(0.063)DS(0.213)S(0.722)PTR;EYIPGQPPLSQSSDS(0.211)S(0.699)PT(0.089)R 260.98 4.232799999999999e-66 2008438900.0 281879.0 299504.0 345979.0 385396.0 344781.0 369102.0 309735.0 399915.0 319751.0 325168.0 True False 371510.65855257044 396312.81088006054 341391.09240133746 296548.9065088446 296914.10950326704 346021.99359125685 337300.8149637982 338117.3258824745 336652.38507539587 313783.9672934366 1.183969537249016 1.2630116646764387 1.0879813119390003 0.9450734818185451 0.9462373494232941 1.1027395586074438 1.0749459823368532 1.0775481258616455 1.0728794972516036 1.0 18.25941211451478 -5.407002176948574 4.630160700384833 1.0345866073600514 1.2212024831919843 0.6546990625860377 0.054890269637931165 0.1425829123210617 4.745384946537358 0.016026378564275065 0.03468498090098976 3.917399134637143e-06 5.407002176948574 0.18661587583193295 EYIPGQPPLSQSSDSS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 EYIPGQPPLSQSSDSSPTR 19 0 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 EYIPGQPPLSQSS(0.019)DS(0.217)S(0.727)PT(0.037)R;EYIPGQPPLSQSSDS(0.049)S(0.659)PT(0.292)R;EYIPGQPPLSQS(0.002)S(0.17)DS(0.067)S(0.75)PT(0.011)R;EYIPGQPPLSQS(0.003)S(0.037)DS(0.428)S(0.531)PTR;EYIPGQPPLSQS(0.001)S(0.189)DS(0.189)S(0.617)PT(0.004)R 272.51 1.1617999999999997e-91 616734200.0 1840382.0 1938107.0 2112814.0 2061998.0 2471875.0 1763847.0 2327486.0 1545944.0 1900944.0 1608831.0 True False 2151922.323398615 2130509.454457058 2163191.4986517127 1946470.9371477095 1987528.8382531598 1671347.7582448167 2107009.6765405987 1505364.6080630678 1928741.7097672776 1900499.3248008152 1.1322931270307872 1.121026156997109 1.1382227135905083 1.0241892284553757 1.0457929725712825 0.8794255995960351 1.1086611023981432 0.7920889991480738 1.014860507761255 1.0 20.857947081971204 -6.109873680695774 1.256437819741403 0.9547911449232909 1.136362621072355 0.42359487564349263 0.08217319135992596 0.41045093434533014 1.3184959190546515 0.02979209439974273 0.04999303949957221 7.764729294385102e-07 6.109873680695774 0.1815714761490641 EYIPGQPPLSQSSDSS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 3 EYIPGQPPLSQSSDSSPTR 19 0 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 EYIPGQPPLSQSS(0.139)DS(0.202)S(0.656)PT(0.003)R;EYIPGQPPLSQS(0.001)S(0.008)DS(0.217)S(0.654)PT(0.12)R;EYIPGQPPLSQS(0.001)S(0.01)DS(0.225)S(0.732)PT(0.032)R 191.71 1.3174e-11 57320900.0 301376.0 403073.0 451878.0 375921.0 451974.0 406806.0 419436.0 410017.0 434693.0 335400.0 True False 297078.3229744101 402139.70923323196 414726.33513952227 403567.484375695 425389.7779350731 389407.85569110286 441152.3437638899 429067.88666064903 385733.2968197791 393373.4431075919 0.7552068605026698 1.0222848447937611 1.054281478340901 1.025914411475192 1.0813891618472182 0.9899190260909291 1.1214593956288756 1.0907393322515022 0.9805778798196015 1.0 18.585540038077063 -4.759907910031255 4.350930761471778 1.0475153078342643 0.7279505261359315 0.7943208866873007 0.04365208466120176 0.09026786858937856 3.573118943998025 0.010592490711218934 0.09182416864597803 1.738169359778619e-05 4.759907910031255 -0.3195647816983328 EYIPGQPPLSQSSDSSPTRNS(ph)EPAGLETPEAK ddPTM_PC-9_AZD4547_30min_R2 1 EYIPGQPPLSQSSDSSPTRNSEPAGLETPEAK 32 1 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 EY(0.001)IPGQPPLS(0.125)QS(0.125)S(0.038)DS(0.161)S(0.161)PT(0.161)RNS(0.228)EPAGLET(0.001)PEAK 48.607 0.0047735 5432500.0 30703.0 17058.0 46797.0 114050.0 85161.0 41449.0 27972.0 37157.0 27271.0 43054.0 True False 40465.91533792725 22571.664912629138 46176.44120338339 87757.53455493497 73337.86513586223 38857.18747761867 30461.45381105581 31415.239432917322 28712.489385150067 41546.69256461771 0.9739864436859919 0.5432842789476768 1.1114348303794583 2.112262833399924 1.765191417386585 0.9352654827381013 0.7331860114659912 0.7561429681570222 0.6910896538994875 1.0 15.342446011525867 -6.9845272733756785 24.514740603274124 0.783274945413158 1.2992960427423876 0.26234008564872424 0.4061229349510744 302.04408034120695 478551.4866222262 0.16544253941020387 0.1458551333897216 1.0362695254196767e-07 6.9845272733756785 0.5160210973292296 EYLDYDDTR ddPTM_PC-9_Lapatinib_30min_R1 1 EYLDYDDTR 9 0 F5H303;Q9BVI4 F5H303 NOC4L Nucleolar complex protein 4 homolog 0 92.051 0.033760000000000005 2048200.0 11793.0 14036.0 16844.0 14773.0 15573.0 16425.0 14146.0 13569.0 16346.0 14049.0 False True 11624.829657428661 14003.500504369276 15459.151339720287 15859.45570128333 14657.026757696009 15722.541038545089 14878.41066309042 14199.465276069875 14504.941348989092 16477.350930884197 0.7055035549215469 0.8498635832366671 0.9382061111986482 0.9625003295619128 0.8895256779549268 0.9541910653292978 0.902961327066427 0.8617565612112573 0.8802957107505592 1.0 14.008196698158214 -4.824724772118702 2.594486215734869 0.9189037471108467 0.6725274679059287 0.7318037986881257 0.04021799235418835 0.22986901430367174 2.183699142534632 0.01061078657144523 0.12080249950768641 1.4971841744437916e-05 4.824724772118702 -0.246376279204918 EYPS(ph)PPPS(ph)PLRR ddPTM_PC-9_AZD4547_30min_R2 1 EYPSPPPSPLRR 12 1 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 2 EY(0.213)PS(0.787)PPPS(1)PLRR 65.374 0.031525 5943900.0 18479.0 20250.0 27109.0 27291.0 33387.0 30404.0 24125.0 34813.0 19664.0 23489.0 True False 24354.937612922447 26795.41648966702 26749.51694729407 20999.48159174685 28751.791351569736 28502.83307364514 26272.07826368228 29433.450773155808 20703.39889514836 22666.65725949518 1.0744829876809487 1.1821512181043934 1.18012623745341 0.926448101779545 1.2684619095974314 1.2574784516012019 1.1590627573757826 1.2985351318543445 0.913385624449569 1.0 14.468284026440573 -8.276987302042935 24.917309378909472 0.9566927690812173 1.167132304208047 0.40240895065561266 0.10316015353377576 910.2659076197341 1458789.2065866129 0.09897613197095928 0.025922456815620797 5.28460702750257e-09 8.276987302042935 0.21043953512682978 EYPS(ph)PPPSPLR ddPTM_PC-9_AZD4547_30min_R2 1 EYPSPPPSPLR 11 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 EY(0.005)PS(0.971)PPPS(0.024)PLR 68.515 0.037018 7565600.0 18751.0 14943.0 29038.0 25015.0 26237.0 27465.0 24664.0 27278.0 24131.0 25372.0 True False 24713.427954970957 19773.032523708367 28652.937146907865 19248.178227897384 22594.445433585985 25747.60920825104 26859.048219500924 23062.81188608117 25406.51539558711 24483.734002635752 1.0093814919043997 0.8075987315325243 1.1702846119723114 0.7861618748931538 0.9228349495691147 1.051621015220931 1.0970160113898257 0.9419646481863585 1.0376895694444326 1.0 14.579535979094635 -6.756897058614263 24.93018396627685 1.0264909030184164 0.9362683342587638 0.1414968347431863 0.10628010654071987 220.4275485663606 1209800.3747077985 0.03450190557939657 0.03340452991221341 1.7502615062209346e-07 6.756897058614263 -0.09022256875965262 EYPS(ph)PPPSPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 EYPSPPPSPLR 11 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 EY(0.002)PS(0.986)PPPS(0.013)PLR;EYPS(0.921)PPPS(0.079)PLR;EY(0.062)PS(0.93)PPPS(0.008)PLR 96.334 0.0058477 29609600.0 83147.0 95296.0 98333.0 84852.0 68587.0 46685.0 48451.0 33171.0 39034.0 30303.9 True False 97222.1448718933 104756.35709067668 100677.63164997895 80098.01753389547 55147.869705899146 44236.75641575452 43861.37052513686 32300.296397579696 39604.79840492713 35797.757184459595 2.715872516004971 2.9263385566555318 2.8124005403803567 2.237514968358614 1.5405398003492732 1.235741004326339 1.2252547079730964 0.9022994438210725 1.1063485961103798 1.0 15.127581581558037 -6.225958415994741 1.355334210795168 1.0592401555820117 2.88318851450337 0.9834014588371676 0.09944578224361193 0.048620641954696 0.18039398504280751 0.03897534763444235 0.056740886936415734 5.943490652364547e-07 6.225958415994741 1.8239483589213585 up EYPS(ph)PPPSPLR ddPTM_PC-9_Lapatinib_30min_R1 1 EYPSPPPSPLR 11 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 EYPS(0.918)PPPS(0.082)PLR 98.182 0.005082 13902000.0 76302.0 88516.0 95408.0 74015.0 49688.0 33264.0 30522.0 31092.0 36052.0 26090.0 True False 75213.91948792693 88311.04664040674 87563.92252553029 79458.31000680185 46765.449530366575 31841.376262171303 32102.279814707024 32536.647826926423 31991.444115609618 30599.62173726024 2.4580016097500055 2.8860175919388253 2.86160146937066 2.5967088968961947 1.528301556532697 1.0405807148720083 1.049107080157695 1.0633022887112205 1.0454849537128297 1.0 14.901226198442808 -6.353311192259254 2.439716844058034 1.0452040622512975 2.761334606935607 0.9797637154998345 0.11307528359217917 0.03762111631054265 0.43845933729710823 0.03919393776795975 0.04678755410328555 4.432908914963311e-07 6.353311192259254 1.7161305446843094 up EYPSPPPS(ph)PLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EYPSPPPSPLR 11 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 EYPS(0.121)PPPS(0.879)PLR 72.73100000000001 0.026503 2594000.0 34176.0 36657.0 40110.0 35573.0 30844.0 18010.0 14278.0 13928.0 13803.0 9147.7 True False 39961.321793231546 40296.06470232674 41066.37451802207 33579.96013922207 24800.339615506622 17065.523895206996 12925.484476231735 13562.404757935836 14004.842762289512 10806.105596846643 3.698031768715342 3.729008970084989 3.8002936534329033 3.1074987967007397 2.2950302857251064 1.5792483001634678 1.1961279075417839 1.255068686529726 1.2960120217940774 1.0 13.399559064656549 -6.409921459072035 1.2660969653196616 1.1825410705161825 3.79279200101361 0.9915713751983257 0.10234469364384367 0.03593201793069487 0.1186868840384194 0.04357980260734841 0.054405569853002 3.8911550907010473e-07 6.409921459072035 2.6102509304974273 up EYQDLLNVK ddPTM_PC-9_Lapatinib_30min_R1 2 EYQDLLNVK 9 0 P08670;B0YJC4;B0YJC5;P17661;P07196;P07197-2;E7EMV2;E7ESP9;P07197;Q16352 P08670;Q16352 VIM;DES;NEFL;NEFM;INA Vimentin;Desmin;Neurofilament light polypeptide;Neurofilament medium polypeptide;Alpha-internexin 0 ; 150.85 0.00088402 57754000.0 151134.0 161853.0 201023.0 164751.0 160353.0 150466.0 154263.0 135848.0 135093.0 157006.0 False True 148978.80144541844 161478.23932271905 184495.66491122005 176867.33813322513 150921.3518061277 144030.91993337753 162249.98332534404 142159.99401750654 119877.40374764365 184144.27790265522 0.8090330209672526 0.8769115237351106 1.001908215734787 0.9604824007983733 0.8195820881597512 0.7821634295338629 0.8811024983959305 0.7720033206389233 0.6509971697899558 1.0 17.490477042080528 -6.354801122185236 6.341618644836404 0.8066726759505898 0.9156925783766868 0.1849292927539633 0.09557517310704854 0.37554565528981476 21.269712973688883 0.029978389991824037 0.03404346213933445 4.417727033797584e-07 6.354801122185236 0.10901990242609705 EYS(ph)APGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EYSAPGVR 8 0 P0C869-4;P0C869;P0C869-6 P0C869-4 PLA2G4B Cytosolic phospholipase A2 beta 1 EY(0.1)S(0.9)APGVR 65.22399999999999 0.029675999999999998 2259000.0 0.0 752.86 0.0 0.0 579.44 961.56 585.2 0.0 0.0 953.06 True False 0.0 827.5989653215948 0.0 0.0 465.9028915448441 911.134100870363 529.7656195188974 0.0 0.0 1125.8422335811917 0.0 0.7350931956861178 0.0 0.0 0.41382609183424707 0.8092911010916124 0.4705504943030658 0.0 0.0 1.0 10.13678895863714 -6.45477902522333 24.054576300850997 0.4185110490488894 0.20963690733021412 0.11367417687876535 0.35380739947759976 368.67196242258956 130222.99243762965 0.11410942910117657 0.12938783096437448 3.5093038655625607e-07 6.45477902522333 -0.2088741417186753 EYS(ph)PPYAPSHQQYPPSHATPLPK ddPTM_PC-9_AZD4547_30min_R2 3 EYSPPYAPSHQQYPPSHATPLPK 23 0 Q9UPT8 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 EY(0.009)S(0.976)PPY(0.008)APS(0.007)HQQYPPSHATPLPK;EY(0.007)S(0.785)PPY(0.085)APS(0.007)HQQY(0.115)PPS(0.002)HATPLPK;EY(0.313)S(0.372)PPY(0.313)APS(0.002)HQQYPPSHATPLPK 87.339 1.608e-05 67254000.0 25812.1 29285.6 82748.0 133754.0 110544.0 94680.0 61749.3 109133.0 73651.0 91444.0 True False 34019.81087496699 38751.597488878666 81650.70745341729 102919.08177870033 95196.87372833522 88759.64463270374 67244.8680757552 92269.00247685668 77544.04149850346 88242.57339338717 0.38552605127806044 0.4391485424628684 0.9252983487847389 1.1663200405532712 1.0788089021831406 1.0058596572995606 0.7620456372682631 1.0456290986156944 0.8787599739732268 1.0 16.42918724400257 -5.271198831871482 4.168843985359409 0.991414858218285 0.39709629517314066 0.830272172830678 0.10363014256617421 0.07724811767238117 3.3128679229424556 0.02904382916989141 0.07339517165862823 5.35551411319008e-06 5.271198831871482 -0.5943185630451444 down EYS(ph)PPYAPSHQQYPPSHATPLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EYSPPYAPSHQQYPPSHATPLPK 23 0 Q9UPT8 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 EY(0.001)S(0.999)PPY(0.001)APSHQQYPPSHATPLPK;EY(0.026)S(0.961)PPY(0.009)APS(0.004)HQQYPPSHATPLPK 110.44 5.5119e-07 39781800.0 58311.0 84047.0 180776.0 184326.0 221926.0 201991.0 208409.0 153257.0 184285.0 142490.0 True False 68181.90060525284 92390.63071272768 185086.38543679772 173998.81181295463 178441.1934091206 191398.236375167 188666.99076950405 149234.16613921404 186979.81949203272 168322.30904978066 0.40506752188795314 0.5488911792756094 1.0995950951579399 1.0337240072051006 1.0601161213653938 1.1370936951593371 1.1208674110673382 0.8865976648114935 1.1108439549550986 1.0 17.360866875243225 -5.18828310429846 4.012501219976461 1.0575971960032922 0.43903999123097504 0.9116441703072142 0.07250630627672723 0.0579169918547046 1.7869754752165212 0.01903134756701586 0.056206451907618374 6.482117448774734e-06 5.18828310429846 -0.6185572047723171 down EYS(ph)PPYAPSHQQYPPSHATPLPK ddPTM_PC-9_Lapatinib_30min_R1 3 EYSPPYAPSHQQYPPSHATPLPK 23 0 Q9UPT8 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 EYS(1)PPYAPSHQQYPPSHATPLPK;EYS(0.999)PPYAPSHQQYPPSHATPLPK;EY(0.006)S(0.937)PPY(0.007)APS(0.049)HQQYPPSHATPLPK 136.61 2.294e-07 72549000.0 145525.0 104909.0 290945.0 147647.0 222447.0 257748.0 155107.0 215485.0 280360.0 151053.0 True False 143449.78681398314 104666.08965608971 267024.6251801779 158505.45291595315 209363.10480762873 246724.71887993423 163137.68151562035 225497.21976666778 248782.90447831756 177162.30978452944 0.8097082668906915 0.590792080908112 1.5072315635585354 0.8946905981793342 1.1817587220569823 1.392647901125295 0.9208374044910212 1.2728284026152337 1.4042654150360503 1.0 17.434712186283647 -5.245991031032871 24.99904748256079 1.1923408288593824 0.7002501151170815 0.48779298322025244 0.2034817888988277 653.5292149395274 1057559.5240762136 0.04948947712084919 0.12991000976173775 5.675563263529402e-06 5.245991031032871 -0.49209071374230096 EYSPPY(ph)APSHQQYPPSHATPLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EYSPPYAPSHQQYPPSHATPLPK 23 0 Q9UPT8 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 EY(0.161)S(0.19)PPY(0.463)APS(0.161)HQQY(0.024)PPS(0.001)HATPLPK 54.15 0.018483000000000003 12117000.0 11726.0 18544.0 34616.0 39193.0 44459.0 47241.0 39099.0 33935.0 42127.0 25896.0 True False 13710.980200943142 20384.92576697349 35441.37672191105 36997.14327542043 35747.578101601925 44763.59879697246 35395.25966775352 33044.24220710459 42743.02767854602 30590.739807376776 0.4482068850664677 0.6663757037369128 1.1585655314346002 1.2094229661781108 1.1685751415852195 1.463305532289807 1.1570579819458358 1.080204088399855 1.3972538077761294 1.0 14.90080737704797 -5.167130480646179 2.355452391347805 1.222487042109616 0.44808660076483703 0.805770092225361 0.12929315717001905 0.13017359981024623 1.3115809247555716 0.034341868471227555 0.14420048098496457 6.805648571697559e-06 5.167130480646179 -0.7744004413447789 down EYTINIHK ddPTM_PC-9_AZD4547_30min_R2 2 EYTINIHK 8 0 H7C2W9;C9JU56;B7Z4E3;B7Z4C8;P62899-3;P62899;P62899-2;B8ZZK4 H7C2W9 RPL31 60S ribosomal protein L31 0 ; 108.74 0.0031801999999999998 10724200.0 101534.0 118635.0 134941.0 146603.0 130383.0 131522.0 123101.0 151212.0 119218.0 130061.0 False True 133819.69996160304 156981.4437161309 133151.59417111683 112805.94334377146 112281.57102440216 123297.90854861046 134056.75052176407 127845.65990608226 125519.62009162919 125507.60397748757 1.0662278278024209 1.2507723734753857 1.0609045982186096 0.898797680529425 0.8946196681799632 0.982393931850747 1.0681165624499531 1.0186287990089753 1.0000957401285724 1.0 16.937415248081273 -5.516786682952708 13.96698079083918 0.981203422966029 1.1578471573928244 0.5537547105219875 0.06401785560532132 0.6402790114707791 1459.918050775857 0.018114755500432716 0.03348288729633559 3.042379016449067e-06 5.516786682952708 0.17664373442679537 EYTINIHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 EYTINIHK 8 0 H7C2W9;C9JU56;B7Z4E3;B7Z4C8;P62899-3;P62899;P62899-2;B8ZZK4 H7C2W9 RPL31 60S ribosomal protein L31 0 ; 99.13600000000001 0.0044418 7836900.0 91668.0 115810.0 120298.0 114974.0 128638.0 87217.0 111366.0 102470.0 91377.0 80730.0 False True 107185.58187447183 127306.85143837362 123166.36055270585 108532.37953073744 103432.3073356098 82643.18698324652 100816.60625998206 99780.27107593934 92713.2157567001 95365.70994167167 1.123942577893349 1.3349331905172 1.291516212987224 1.1380650298426853 1.0845859313465174 0.8665922692107404 1.057157822467261 1.0462908642631377 0.9721860804413461 1.0 16.541182998087734 -6.161831731459738 2.1831838813844024 0.9968139763175147 1.2557332054622647 0.6950247392082836 0.07387503504403964 0.1719975044596156 1.6094911213696084 0.024198383141989292 0.03344635736019716 6.889191681860813e-07 6.161831731459738 0.2589192291447501 EYTINIHK ddPTM_PC-9_Lapatinib_30min_R1 2 EYTINIHK 8 0 H7C2W9;C9JU56;B7Z4E3;B7Z4C8;P62899-3;P62899;P62899-2;B8ZZK4 H7C2W9 RPL31 60S ribosomal protein L31 0 ; 109.71 0.0031671 16264700.0 148473.0 172278.0 178343.0 173180.0 182344.0 182049.0 186809.0 171771.0 189130.0 175449.0 False True 146355.74779338646 171879.1008757287 163680.3269638885 185916.23491154448 171618.8844220971 174263.1886469462 196481.05595654304 179752.1077408655 167828.1877728074 205775.1258789028 0.7112412016188768 0.835276373378959 0.7954330061263732 0.9034922667035804 0.8340118062816474 0.8468622623975399 0.9548338513575774 0.8735366190306614 0.8155902568689138 1.0 17.650709074064203 -1.5228787452803376 0.12177419331282734 1.001924511368782 0.24639830874737964 0.5420526229590756 0.052553371514530586 78.36441961660542 0.6566920813405162 0.350217210533325 10.059567118745338 0.029999999999999995 1.5228787452803376 -0.7555262026214024 EYVNAS(ph)EVSSGKPVSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EYVNASEVSSGKPVSAR 17 1 O15231-7;O15231;O15231-8;O15231-6;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 EY(0.427)VNAS(0.573)EVS(0.001)SGKPVSAR 57.703 0.021071 5226400.0 14069.0 4009.9 18070.0 19075.0 18596.0 11161.0 18046.0 11779.0 16836.0 14338.0 True False 16450.603824583748 4407.97637149412 18500.85733085661 18006.289591984405 14952.247292502956 10575.697512182416 16336.55223827413 11469.813730882122 17082.194649417248 16937.365900454442 0.971261052118049 0.2602515879624382 1.0923101879944754 1.0631103855116741 0.8827964974235915 0.6244003686487438 0.9645273258125578 0.6771899360439736 1.008550842546238 1.0 14.047921903697716 -1.5228787497850274 0.043274682707303995 1.3369364428555122 2.4598519216136473e-05 0.050818523120770065 0.2404328581012316 2322.5442566292168 7.661739136302929 61.796537710730526 220.08490660491836 0.029999999688827054 1.5228787497850274 -1.336911844336296 EYVSNDAAQS(ph)DDEEKLQSQPTDTDGGR ddPTM_PC-9_AZD4547_30min_R2 2 EYVSNDAAQSDDEEKLQSQPTDTDGGR 27 1 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 EYVS(0.003)NDAAQS(0.992)DDEEKLQS(0.004)QPTDTDGGR;EYVS(0.007)NDAAQS(0.985)DDEEKLQS(0.007)QPTDTDGGR 107.95 2.0695e-10 39333000.0 80760.0 74760.0 74675.0 91766.0 91991.0 81482.0 89989.0 78091.0 80007.0 77546.0 True False 106440.00008764607 98924.70798851896 73684.76070822185 70610.76647056697 79219.63753024382 76386.91765908286 97997.84666820732 66023.8303026602 84236.00668247223 74831.13814316528 1.422402528263133 1.3219725162974054 0.9846804757566266 0.9436013967270686 1.0586453646967464 1.0207905365937517 1.3095864783015863 0.8823042377939629 1.1256812173738926 1.0 16.191351097482688 -5.149795930448526 4.215865601083968 1.0428564797142956 1.399447451688961 0.5958086843477313 0.11019963756975669 0.14935097624477747 4.398672224656938 0.028148283698190404 0.08434984385017977 7.082785174313936e-06 5.149795930448526 0.3565909719746654 EYVSNDAAQS(ph)DDEEKLQSQPTDTDGGR ddPTM_PC-9_Lapatinib_30min_R1 2 EYVSNDAAQSDDEEKLQSQPTDTDGGR 27 1 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 EYVS(0.005)NDAAQS(0.995)DDEEKLQSQPTDTDGGR;EYVSNDAAQS(0.999)DDEEKLQSQPTDTDGGR 116.92 2.9682e-12 115806000.0 64362.0 80661.0 69556.0 78680.0 78294.0 68034.0 78564.0 79305.0 73407.0 69538.0 True False 63444.186077454746 80474.23441029698 63837.37417392448 84466.38966878587 73688.90085192652 65124.34441500012 82631.6595033956 82989.79981713636 65139.13065002092 81557.55064643944 0.7779069574133236 0.9867171558297679 0.7827279469275163 1.0356660909908457 0.9035202782312045 0.7985078499637759 1.013169949911965 1.017561208733522 0.7986891481379315 1.0 16.315530828232838 EYVTCHTCR ddPTM_PC-9_AZD4547_30min_R2 2 EYVTCHTCR 9 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 0 ; 96.665 0.0042232 7633400.0 61071.0 53222.0 148754.0 213370.0 148097.0 99448.0 89810.0 172357.0 114774.0 102585.0 False True 80490.30764428731 70424.97068706465 146781.42476586316 164180.84303363855 127536.2878902992 93229.50083896412 97802.91601497668 145723.18601984388 120840.71932423492 98993.53037444386 0.8130865455533514 0.711409830730166 1.4827375507334792 1.6585007364887698 1.2883295242415551 0.9417736743635947 0.9879728063544793 1.4720475718831798 1.220693098500012 1.0 16.595046621896273 -5.249738054395637 24.94916687608288 1.268028186398345 0.7622481081442041 0.43576401885058047 0.22466126945335724 714.506480249194 1523439.1887233774 0.06253414368876334 0.1624863212937403 5.626806048182552e-06 5.249738054395637 -0.5057800782541408 EYVTCHTCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 EYVTCHTCR 9 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 0 76.282 0.020766 1751700.0 25544.0 23340.0 40902.0 28466.0 39754.0 29911.0 26770.0 34187.0 29584.0 20277.0 False True 29868.09468300287 25657.0409513137 41877.25880169883 26871.14230801718 31964.48907647682 28342.414504693865 24234.15180198373 33289.62747412065 30016.61003257068 23953.059587356318 1.2469427788159813 1.0711383594961217 1.7483052070643972 1.1218250516189248 1.3344637230957066 1.1832481942997577 1.0117351277652975 1.389786025151153 1.2531430451755325 1.0 14.547922326516538 -6.770370675151909 23.55665999946087 1.1822035810939122 1.3060718859106377 0.10289501724622685 0.19984867616328103 264.8058781621933 698428.7478386639 0.06951768878029681 0.062307504556483345 1.6967948010826139e-07 6.770370675151909 0.1238683048167255 EYVTCHTCR ddPTM_PC-9_Lapatinib_30min_R1 1 EYVTCHTCR 9 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 0 96.34200000000001 0.0043103 3695500.0 28044.0 41922.0 63070.0 49232.0 53724.0 51657.0 48280.0 40443.0 64109.0 38450.0 False True 27644.08741736025 41824.93218468 57884.62805724049 52852.68551313754 50564.05994544788 49447.75052834846 50779.7021641457 42322.129424430284 56888.369322301594 45096.031268595485 0.6130048840154005 0.9274637037473972 1.28358585952886 1.1720030349975326 1.121252991073303 1.0964989409785042 1.1260348357862764 0.9384890029979883 1.2614939213490877 1.0 15.460712852474545 -4.890730450455174 3.268328176980507 1.1232293269999976 0.5959191046369027 0.7122268785722428 0.10006576282309117 0.14243320601888176 2.609599804584215 0.025037769779044223 0.16457119974937773 1.2860846345537494e-05 4.890730450455174 -0.5273102223630949 EYYDHLPELK ddPTM_PC-9_Lapatinib_30min_R1 1 EYYDHLPELK 10 0 P11216;H0Y4Z6 P11216 PYGB Glycogen phosphorylase, brain form;Alpha-1,4 glucan phosphorylase 0 73.84100000000001 0.022580000000000003 2110200.0 44235.0 37183.0 42675.0 36459.0 42290.0 36491.0 40154.0 34700.0 42510.0 34751.0 False True 43604.200788294474 37096.9050480167 39166.4262302638 39140.31648365865 39802.585345338965 34930.3649946757 42232.97764496905 36312.288678578014 37722.076149854794 40757.664047203165 1.0698405271164366 0.910182315773868 0.9609585619260101 0.9603179524304584 0.9765668930202162 0.8570256861193364 1.036197206887452 0.8909315469238674 0.9255210530752516 1.0 15.314783747930296 -4.751499476559618 24.886245595284187 0.944846922070344 1.0698407956105953 0.35303778255822293 0.05008632327346337 414.8897100285622 1038671.7862604617 0.011641454939390901 0.15281052794074096 1.7721501810462255e-05 4.751499476559618 0.12499387354025127 FAAATGATPIAGR ddPTM_PC-9_Lapatinib_30min_R1 2 FAAATGATPIAGR 13 0 C9J9K3;A0A0C4DG17;P08865;F8WD59 C9J9K3 RPSA 40S ribosomal protein SA 0 ; 178.54 0.0005657 27275000.0 51481.0 53922.0 65672.0 56598.0 67549.0 71058.0 56576.0 43666.0 56693.0 51624.0 False True 50746.87149954086 53797.14692195782 60272.70166125088 60760.40572539324 63575.90062644361 68019.0149842884 59505.22845150595 45694.88177057022 50307.63733624366 60547.13961534391 0.8381382146528444 0.8885167369380484 0.9954673671483651 1.0035223151977815 1.0500231890447909 1.1234059183706004 0.9827917359852633 0.754699265082874 0.830883798241307 1.0 15.885771184882211 -5.067935787742617 3.7394227520224415 0.9689052132178918 0.84520440432472 0.15752927381300152 0.09932429641784182 0.4721069035238043 12.551401348383905 0.029608093577192508 0.10380631009812537 8.55193147424745e-06 5.067935787742617 -0.12370080889317181 FAAYFQQGDMESNGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FAAYFQQGDMESNGK 15 0 P06744-2;P06744;A0A2U3TZU2;K7EQ48;CON__Q3ZBD7 P06744-2 GPI Glucose-6-phosphate isomerase 0 84.821 0.037478 0.0 7686.2 8013.0 10502.0 11374.0 11669.0 10206.0 10788.0 9711.4 7760.4 8250.3 False True 8987.321850630151 8808.477683927882 10752.407509056793 10736.751655005533 9382.543216617396 9670.779393363835 9766.08254164365 9456.486040078846 7873.881168765597 9746.014080661133 0.9221535877383511 0.9038030943754135 1.103262053601239 1.101655668270612 0.9627056906510153 0.9922804659756664 1.0020591454943963 0.9702926716310832 0.8079078383838599 1.0 13.250596591543363 -8.017148588428364 22.172400442769494 0.8990026085630135 0.9999935296893359 0.19711573898403656 0.07500940351403333 256.93360083684576 332197.0614196888 0.0497977990233082 0.019916262752167277 9.612833310384513e-09 8.017148588428364 0.10099092112632235 FAAYFQQGDMESNGK ddPTM_PC-9_Lapatinib_30min_R1 3 FAAYFQQGDMESNGK 15 0 P06744-2;P06744;A0A2U3TZU2;K7EQ48;CON__Q3ZBD7 P06744-2 GPI Glucose-6-phosphate isomerase 0 ;; 147.33 0.00038915 13879800.0 91554.0 67093.0 81271.0 72781.0 81487.0 73640.0 74712.0 66044.0 74862.0 74255.0 False True 90248.42317105261 66937.65028068157 74589.21209513239 78133.55753029858 76694.09486960605 70490.58886322436 78580.22179137637 69112.64534547576 66430.25322819165 87089.87781143167 1.0362676517523641 0.7686042507214902 0.8564624726725888 0.8971600316109589 0.8806315589931735 0.8094004795350805 0.9022888051527581 0.7935783937499546 0.7627781195425196 1.0 16.41021742811111 -6.703327770334413 24.796617151332864 0.8437502124413423 0.87997816565057 0.027378549690950882 0.08704800036000915 290.8871484513206 124121.43510637709 0.027610131610067982 0.02761012015069741 1.9800320937372488e-07 6.703327770334413 0.03622795320922767 FACNGTVIEHPEYGEVIQLQGDQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FACNGTVIEHPEYGEVIQLQGDQR 24 0 K7EM18;P41567;O60739;K7EQP2 K7EM18 EIF1;EIF1B Eukaryotic translation initiation factor 1;Eukaryotic translation initiation factor 1b 0 77.053 0.0010012 0.0 1705.5 3751.3 3379.2 5608.5 5701.4 4685.7 1773.8 2154.1 2492.2 2027.6 False True 1994.207464839548 4123.704272521985 3459.772943687364 5294.273928002335 4584.25159784235 4439.973643296583 1605.7728228001022 2097.5571574576093 2528.643710220816 2395.187829527232 0.832589177456354 1.721662168488862 1.4444683214553 2.210379437777676 1.9139424229402502 1.8537058298985074 0.6704162416845001 0.8757380659668891 1.0557183361773868 1.0 11.225923080540912 -7.258927904756874 24.994222157890853 0.8901129858581628 1.691849760852809 0.5298334468615316 0.35111030064354753 179.3158270425064 1784564.3464287145 0.14385623975502965 0.10618097589108243 5.5089914106499336e-08 7.258927904756874 0.8017367749946461 FACNGTVIEHPEYGEVIQLQGDQR ddPTM_PC-9_Lapatinib_30min_R1 2 FACNGTVIEHPEYGEVIQLQGDQR 24 0 K7EM18;P41567;O60739;K7EQP2 K7EM18 EIF1;EIF1B Eukaryotic translation initiation factor 1;Eukaryotic translation initiation factor 1b 0 ; 211.43 4.3118e-31 9000800.0 36041.0 36151.0 36525.0 28257.0 36083.0 33297.2 32990.0 32267.5 37095.0 29249.0 False True 35527.04873089009 36067.29458061083 33522.05549057727 30335.11404258873 33960.66888190747 31873.15637556426 34698.06077869028 33766.76584830016 32916.970472332716 34304.6506781573 1.0356335956952663 1.0513820682504678 0.9771869069613257 0.8842857584293643 0.9899727357821821 0.9291205636983432 1.0114681272875772 0.9843203525112814 0.9595483359138779 1.0 15.066116555232957 -5.3156542262285145 5.346107983535561 0.9640246465606537 1.0436191873146023 0.43013190885546637 0.035264598590155814 0.17074471784684236 10.879942303451383 0.009315914806373941 0.02044516559514895 4.834435538165119e-06 5.3156542262285145 0.07959454075394867 FADLSEAANR ddPTM_PC-9_Lapatinib_30min_R1 4 FADLSEAANR 10 0 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 0 ;;; 173.39 0.0007751 61321000.0 271157.0 263582.0 268709.0 261842.0 266545.0 264192.0 259951.0 237612.0 260574.0 249849.0 False True 267290.2514558959 262971.6920734298 246616.78326673602 281098.7341593064 250867.34714763256 252893.12402163175 273409.99082998844 248652.3209652531 231225.41215413468 293035.0667471341 0.9121442509354899 0.8974069042062922 0.841594782509585 0.9592665385739386 0.8561000904513285 0.8630131773268568 0.9330282340096842 0.8485411787928447 0.7890707918368821 1.0 18.16071379299234 FADQDDIGNVSFDR ddPTM_PC-9_Lapatinib_30min_R1 1 FADQDDIGNVSFDR 14 0 H0YEN2;E9PQP7;H7BXH2;E9PKF6;Q5H9R7-4;Q5H9R7-6;Q5H9R7-2;Q5H9R7;Q5H9R7-5;Q5H9R7-3 H0YEN2 PPP6R3 Serine/threonine-protein phosphatase 6 regulatory subunit 3 0 124.47 0.00017515 2861700.0 7225.3 12155.0 11306.0 9126.7 11149.0 7715.9 11230.0 9548.1 10202.0 10860.0 False True 7122.265897042261 12126.855844300979 10376.464322422085 9797.907963778687 10493.23773977735 7385.9089436414 11811.434451187988 9991.739583052762 9052.943328177333 12737.136529959598 0.5591732396280479 0.9520865082804797 0.8146622514420829 0.7692394550951528 0.8238302003826158 0.5798720086158037 0.927322591180975 0.7844572883042226 0.7107518481005125 1.0 13.636753357429717 -11.471853826710976 2.6004052970854294 1.1643287756455531 0.7769310724510553 0.24317558047540988 0.12151808502171127 49548654.85665842 26509048.133635245 49266107.834884316 0.028329300651950887 3.3740085072594663e-12 11.471853826710976 -0.38739770319449784 FADSDQDRDPHR ddPTM_PC-9_AZD4547_30min_R2 2 FADSDQDRDPHR 12 1 E9PCT3;P51636-3;P51636-2;P51636 E9PCT3 CAV2 Caveolin;Caveolin-2 0 ; 70.72800000000001 0.013104 12675900.0 56482.0 77627.0 98508.0 66859.0 68071.0 58683.0 104740.0 112474.0 85315.0 76176.0 False True 74442.101101417 102718.40967127812 97201.71955601622 51445.69051125287 58620.51664098919 55013.54273321664 114061.65709173413 95093.72769539888 89824.57672597555 73509.10142616987 1.0126923014585372 1.3973563501445478 1.3223086348517323 0.6998547052424962 0.7974593010073142 0.7483909021588359 1.5516671388820324 1.2936320244766955 1.2219517717298232 1.0 16.165635265818104 -7.261206679066557 24.999999977420647 1.2912820583051643 1.0068711691361183 0.2192241070836486 0.24787008079769413 36.03925338502365 3872125.343789359 0.10930060693750665 0.07924615426852137 5.480161041071144e-08 7.261206679066557 -0.284410889169046 FADSDQDRDPHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FADSDQDRDPHR 12 1 E9PCT3;P51636-3;P51636-2;P51636 E9PCT3 CAV2 Caveolin;Caveolin-2 0 ; 73.9 0.0097151 17519900.0 63488.0 73962.0 71234.0 49969.0 82027.0 39807.0 55248.0 35846.0 38594.0 40215.0 False True 74235.26445484208 81304.45856217074 72932.48871644956 47169.39893168381 65954.39818574642 37719.45084378152 50014.509479118286 34905.08048197646 39158.36423732534 47505.66115823518 1.5626614311834133 1.711468835079595 1.535237841938899 0.9929216388457088 1.38834817951614 0.7939990713557891 1.0528115651843357 0.73475622969886 0.8242883749558587 1.0 15.535811826429878 -5.935509520009193 0.7655110763197784 0.8564292568637601 1.7400901116624488 0.7418396551370052 0.17243026812578788 0.40026667255347076 0.4512798224563609 0.08529322275323677 0.23264682410267767 1.1600867860346752e-06 5.935509520009193 0.8836608547986886 FADSDQDRDPHR ddPTM_PC-9_Lapatinib_30min_R1 2 FADSDQDRDPHR 12 1 E9PCT3;P51636-3;P51636-2;P51636 E9PCT3 CAV2 Caveolin;Caveolin-2 0 ; 74.962 0.0091306 12181800.0 39429.0 123467.0 62060.0 50354.0 74112.0 58407.0 51205.0 49044.0 86142.0 34141.0 False True 38866.73522960697 123181.1197472899 56957.66635852772 54057.201136019794 69752.87786979818 55909.06876336695 53856.14435201076 51322.76328392449 76439.78084452586 40042.22635997704 0.9706437119703966 3.076280490497695 1.4224400473260894 1.350004883595858 1.741983006707077 1.3962527523007342 1.3449837645851028 1.2817160270394596 1.9089792899459972 1.0 15.28923457023693 FAEAFEAIPR ddPTM_PC-9_Lapatinib_30min_R1 1 FAEAFEAIPR 10 0 P50990-2;P50990;P50990-3 P50990-2 CCT8 T-complex protein 1 subunit theta 0 114.5 0.0055421 4429200.0 24278.0 13960.0 21567.0 16837.0 17385.0 17640.0 17709.0 18054.0 17592.0 13090.0 False True 23931.791267960067 13927.676477699844 19793.844511027506 18075.2491465855 16362.448480225064 16885.578320848417 18625.885369197527 18892.85474936737 15610.603708027422 15352.589058671378 1.5588114276036733 0.9071874733619134 1.2892838097459294 1.1773420807076393 1.065777792768009 1.0998521654112265 1.2132080978665511 1.2305973068885339 1.0168059373158504 1.0 13.906194351570596 -4.74183289113495 24.95276355255146 1.1273820547263198 1.5588129375825417 0.5812904931188915 0.1132341151205906 989.1527562001664 1258807.1998999543 0.026913259726417883 1.0315326637288034 1.812037198482701e-05 4.74183289113495 0.4314308828562219 FAEHVFR ddPTM_PC-9_AZD4547_30min_R2 2 FAEHVFR 7 0 E5RK89;E5RI78;E9PC71;E5RIA5;E5RIZ1;E5RIG4;E5RFL9;E5RHC8;E5RHE8;A0A1B0GXG3;E5RI95;E5RGZ0;E5RJJ6;E5RJT1;E5RGA9;P61601;P37235;P84074 E5RK89 NCALD;HPCAL1;HPCA Neurocalcin-delta;Hippocalcin-like protein 1;Neuron-specific calcium-binding protein hippocalcin 0 ; 110.63 0.0079197 5770800.0 35183.0 38269.0 40318.0 47118.0 47283.0 41335.0 40352.0 60136.0 48843.0 51383.0 False True 46370.462148138395 50638.705858916896 39783.356976686795 36255.67306584326 40718.57161398966 38750.31591564014 43943.249827817934 50843.36298780621 51424.74126503924 49584.09680976795 0.9351881980636082 1.0212690987030582 0.8023410636946313 0.7311955929123827 0.8212022449498001 0.7815069429278465 0.8862367705598948 1.025396573882741 1.0371216695210366 1.0 15.597589856358477 -7.696233120291634 4.123061775381565 1.0250864820265095 0.8470833187824117 0.4989079260258681 0.0771459344009387 0.20110915639162835 6.727447097372208 0.045642970815538836 0.024158744406081716 2.0126436144095803e-08 7.696233120291634 -0.17800316324409782 FAEHVFR ddPTM_PC-9_Lapatinib_30min_R1 1 FAEHVFR 7 0 E5RK89;E5RI78;E9PC71;E5RIA5;E5RIZ1;E5RIG4;E5RFL9;E5RHC8;E5RHE8;A0A1B0GXG3;E5RI95;E5RGZ0;E5RJJ6;E5RJT1;E5RGA9;P61601;P37235;P84074 E5RK89 NCALD;HPCAL1;HPCA Neurocalcin-delta;Hippocalcin-like protein 1;Neuron-specific calcium-binding protein hippocalcin 0 85.265 0.0092201 0.0 9186.6 10961.0 11961.0 8317.7 9781.5 10592.0 8109.6 9351.7 10981.0 10631.0 False True 9055.597399383892 10935.620477941828 10977.612750795197 8929.411405033801 9206.171401168916 10139.004851157959 8529.475407422457 9786.214122059302 9744.204144943671 12468.554185082929 0.7262748563275914 0.8770560175312816 0.8804238717531936 0.7161545173951868 0.7383511563981454 0.8131660415999166 0.6840789461882366 0.7848716039400372 0.7815023298051186 1.0 13.606006563967895 -14.238688030466033 8.530900731136828 0.9546632891542712 0.7916594493774669 0.0 0.09142250025421625 0.0 0.0 0.0 0.020010202016436277 5.771809245797269e-15 14.238688030466033 -0.16300383977680433 FAELPEFRPEEVLPS(ph)PT(ph)LQSLATSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FAELPEFRPEEVLPSPTLQSLATSPR 26 1 I3L2J0;A0A0A0MQR4;Q96RK0;I3L373;I3L135;I3L1Q4 I3L2J0 CIC Protein capicua homolog 2 FAELPEFRPEEVLPS(0.397)PT(0.397)LQS(0.427)LAT(0.39)S(0.39)PR 56.247 0.016175 1061100.0 572.97 828.83 2141.1 1020.4 3119.3 4098.4 4062.5 3391.1 3041.7 2887.4 True False 669.962504326658 911.1107648533565 2192.1519441669666 963.2302961814348 2508.095557082408 3883.472689179141 3677.6705900470256 3302.087218167448 3086.1791081689503 3410.8627633541746 0.1964202463742136 0.2671203235269977 0.6426971989958482 0.2824007774602498 0.7353258489403416 1.1385602290724273 1.078222973248703 0.968109081855947 0.9048089361220922 1.0 11.735920993699771 -6.473924460347116 3.42278454360456 1.0179381956739633 0.36423136811496637 0.8605091715716566 0.1269051137746144 0.09125751087233167 2.152744969171773 0.04424999300580194 0.0485899386974523 3.357960163403102e-07 6.473924460347116 -0.6537068275589969 down FAELPEFRPEEVLPS(ph)PTLQS(ph)LATSPR ddPTM_PC-9_AZD4547_30min_R2 1 FAELPEFRPEEVLPSPTLQSLATSPR 26 1 I3L2J0;A0A0A0MQR4;Q96RK0;I3L373;I3L135;I3L1Q4 I3L2J0 CIC Protein capicua homolog 2 FAELPEFRPEEVLPS(0.563)PT(0.451)LQS(0.396)LAT(0.297)S(0.293)PR 53.091 0.03185 1194000.0 2176.3 804.39 1873.9 3578.7 2527.3 3344.7 2656.7 2910.9 1997.1 3054.4 True False 2868.3181301479012 1064.3933367962104 1849.0508616154902 2753.686005363835 2176.428019373474 3135.5553802598647 2893.141153290146 2461.087290827543 2102.6626288395437 2947.466385687005 0.9731470201243174 0.36112145060073964 0.6273356909495365 0.9342552704708783 0.7384063919922144 1.063813787830194 0.9815688373374963 0.8349840061887269 0.7133796806132017 1.0 11.525259644778341 -5.755572764938717 24.876711573548558 0.892416547405893 0.624593298926976 0.2847416149106552 0.17338866619233487 153.67677599638947 651639.6006865103 0.04637433350830969 0.07763393473781499 1.755606722103305e-06 5.755572764938717 -0.26782324847891703 FAELPEFRPEEVLPS(ph)PTLQSLAT(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 FAELPEFRPEEVLPSPTLQSLATSPR 26 1 I3L2J0;A0A0A0MQR4;Q96RK0;I3L373;I3L135;I3L1Q4 I3L2J0 CIC Protein capicua homolog 2 FAELPEFRPEEVLPS(0.973)PT(0.229)LQS(0.152)LAT(0.366)S(0.28)PR 74.446 0.00031481 7292700.0 6891.1 6484.7 7953.3 12414.0 10970.0 8239.0 8740.5 9555.6 10092.0 8668.8 True False 9082.326456215695 8580.752459779937 7847.834045406099 9552.144094388097 9447.004855983469 7723.814027554349 9518.38756740788 8079.001585843436 10625.442516773654 8365.307950577364 1.0857133425182324 1.0257545221856061 0.9381404835029953 1.1418759656933872 1.1293074817803268 0.9233149661897696 1.1378406657164286 0.9657745576821034 1.2701794816818786 1.0 13.030202935576417 -8.236161320356635 24.999620849194585 1.1350899262856644 1.0446466750936627 0.12250408084018027 0.0980478202715711 1358.1360402363432 1343180.6555335068 0.06246419792674084 0.02358803784737457 5.805487304048044e-09 8.236161320356635 -0.0904432511920017 FAELPEFRPEEVLPS(ph)PTLQSLATS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 FAELPEFRPEEVLPSPTLQSLATSPR 26 1 I3L2J0;A0A0A0MQR4;Q96RK0;I3L373;I3L135;I3L1Q4 I3L2J0 CIC Protein capicua homolog 2 FAELPEFRPEEVLPS(0.747)PT(0.247)LQS(0.168)LAT(0.296)S(0.543)PR 58.326 0.010947 7700800.0 18421.0 16808.0 20842.0 30038.0 27545.0 23298.0 18819.0 21434.0 18808.0 19305.0 True False 24278.494819397372 22240.8573016456 20565.621462079114 23113.203182473782 23720.85221130944 21841.172376982784 20493.854542766298 18121.867804320846 19802.152482707002 18629.13782598469 1.3032538084254617 1.193874751982517 1.103949181877507 1.2407017113929197 1.273319915977143 1.1724199252269107 1.1000967803341186 0.9727700752228972 1.0629666637114115 1.0 14.185273286090986 -7.382852760638369 2.356395880433402 1.014004726581723 1.2153181990836497 0.7336404757992379 0.055311352695263084 0.16841958464268758 1.8249597291633533 0.029423384809037525 0.017616078113341725 4.14140057405081e-08 7.382852760638369 0.20131347250192677 FAELPEFRPEEVLPS(ph)PTLQSLATSPR ddPTM_PC-9_Lapatinib_30min_R1 1 FAELPEFRPEEVLPSPTLQSLATSPR 26 1 I3L2J0;A0A0A0MQR4;Q96RK0;I3L373;I3L135;I3L1Q4 I3L2J0 CIC Protein capicua homolog 1 FAELPEFRPEEVLPS(0.599)PT(0.037)LQS(0.148)LAT(0.097)S(0.119)PR 72.10300000000001 8.4102e-05 1720400.0 4203.1 1328.7 4683.3 2261.9 3562.4 4323.0 4187.7 5075.9 5046.7 3057.6 True False 4143.163023245863 1325.6234767850851 4298.257152060794 2428.2476714772074 3352.8666359478734 4138.1153674052 4404.51861542653 5311.744844483979 4478.287501893018 3586.1020860040962 1.1553388397435405 0.3696558115171211 1.1985875050339783 0.6771273135124112 0.9349612909887596 1.1539312791890424 1.2282189714053497 1.4812029097595276 1.2487897428717825 1.0 11.808200842828088 -6.8158707544274995 2.2785251913038675 1.27623295176017 0.83606126791748 0.34783713086155243 0.2447545094543811 0.29612514604137574 3.151290028316878 0.09117440822971742 0.08125068046422429 1.5280207279115804e-07 6.8158707544274995 -0.44017168384269 FAELPEFRPEEVLPSPTLQSLAT(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FAELPEFRPEEVLPSPTLQSLATSPR 26 1 I3L2J0;A0A0A0MQR4;Q96RK0;I3L373;I3L135;I3L1Q4 I3L2J0 CIC Protein capicua homolog 1 FAELPEFRPEEVLPS(0.001)PT(0.002)LQS(0.028)LAT(0.485)S(0.485)PR 83.87100000000001 1.4831999999999998e-06 15256000.0 28676.0 27326.0 30735.0 32989.0 24447.0 14303.0 14184.0 13818.0 15192.0 11823.0 True False 33530.28042318313 30038.744688757408 31467.838963136597 31140.733281781017 19656.785844257887 13552.925501007532 12840.388836732813 13455.2921413812 15414.154259559691 13966.416309183493 2.4007791033076678 2.150783996679642 2.2531076166221107 2.229686742282249 1.4074323297475204 0.9703939221757214 0.9193760627262506 0.963403341523895 1.103658513274035 1.0 13.769674261697787 -6.399261998002622 2.5130674081183293 0.9847207621051729 2.2677494163889054 0.9836429746678376 0.07716024443992103 0.03412107467167948 0.4210765674376255 0.02733803213549948 0.03162778485485126 3.9878425412938195e-07 6.399261998002622 1.2830286542837324 up FAELPEFRPEEVLPSPTLQSLATS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FAELPEFRPEEVLPSPTLQSLATSPR 26 1 I3L2J0;A0A0A0MQR4;Q96RK0;I3L373;I3L135;I3L1Q4 I3L2J0 CIC Protein capicua homolog 1 FAELPEFRPEEVLPS(0.056)PT(0.002)LQS(0.002)LAT(0.293)S(0.647)PR 89.96799999999999 2.8137e-07 8822700.0 5641.4 5976.8 8481.9 7643.3 7939.0 4112.1 3653.8 3244.3 2298.5 1539.3 True False 6596.377597271075 6570.137204704871 8684.140663784874 7215.070680912943 6383.409940588356 3896.4542370616714 3307.685612778786 3159.140562619994 2332.111214165215 1818.3629049079036 3.6276463732662694 3.6132155946272095 4.7758017062192035 3.967893681420196 3.5105258270277258 2.142836408807525 1.8190459142402675 1.73735427295246 1.2825334304118636 1.0 10.828424442864007 -6.821084081103807 1.6638809348641224 1.4665054040168521 4.04400761035411 0.9135863107143615 0.3619151705626841 0.10508823119454094 0.6014610557100586 0.1675735174385574 0.14564752920658547 1.509787825061624e-07 6.821084081103807 2.577502206337258 up FAGGLHFS(ph)GPK ddPTM_PC-9_AZD4547_30min_R2 1 FAGGLHFSGPK 11 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 FAGGLHFS(1)GPK 61.11 0.034411000000000004 2983700.0 33417.0 49037.0 47181.0 58087.0 59838.0 63229.0 57679.0 64199.0 57745.0 58528.0 True False 44042.910883220335 64887.251279200056 46555.34911248222 44695.9395852039 51530.52657906463 59275.28063457138 62812.31926097126 54278.519696258 60797.28281124601 56478.95253453669 0.7798110429949677 1.1488749059133438 0.8242955476912178 0.7913733803379672 0.9123846011052327 1.0495109766478892 1.1121367596639071 0.9610397725252937 1.0764591070287408 1.0 15.78542571201048 -6.731389663467166 5.994531072884195 1.0421700619457233 0.895342060610647 0.3377826590990941 0.10398053805934539 0.22353372603330324 23.23226052366857 0.03538376051080793 0.034436773972571846 1.856138318655143e-07 6.731389663467166 -0.14682800133507623 FAGGLHFS(ph)GPK ddPTM_PC-9_Lapatinib_30min_R1 1 FAGGLHFSGPK 11 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 FAGGLHFS(1)GPK 58.098 0.041667 4256200.0 63512.0 78816.0 55658.0 53864.0 50197.0 42280.0 38845.0 37981.0 35780.0 42727.0 True False 62606.30723332569 78633.50639444042 51082.01408609311 57825.33824503659 47244.51115109909 40471.78295949384 40856.20402995525 39745.73591645738 31750.079619896576 50112.30501985119 1.2493200464142529 1.569145669178279 1.0193507176701968 1.153914956059794 0.9427726609738651 0.8076216598590223 0.8152928510027769 0.7931332613958336 0.6335785114518139 1.0 15.612877278606643 -5.879933265882828 0.8728724853890427 0.7839584674020433 1.4299299937875682 0.7077954510109155 0.13903900517881201 0.36163413709270287 0.530327802351792 0.05943310656894673 0.1634569142410109 1.3184593187471567e-06 5.879933265882828 0.6459715263855249 FAGHSEAGGGS(ph)GDR ddPTM_PC-9_AZD4547_30min_R2 1 FAGHSEAGGGSGDR 14 0 O96013 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 FAGHSEAGGGS(1)GDR 80.545 0.019326 0.0 7175.5 7039.0 10057.0 12294.0 9922.7 10231.0 7670.0 12542.0 7527.8 10451.0 True False 9457.159740328203 9314.219094852657 9923.637608872928 9459.808240406568 8545.104383269567 9591.253952653053 8352.615141241164 10603.922086488385 7925.70413969171 10085.113671036825 0.9377345708544639 0.9235611415666954 0.983988672073411 0.9379971856513571 0.8472987674705175 0.9510308228054906 0.8282122952395491 1.0514429913607728 0.7858814881237615 1.0 13.29993972445391 -6.017914805659586 24.364945128573634 0.9094355077751514 0.9484500203361376 0.049989944596793845 0.07603898757435737 1703.0955210965244 2316289.271218404 0.020573540521547425 0.027164979621996887 9.595888529298312e-07 6.017914805659586 0.0390145125609862 FAGHSEAGGGS(ph)GDR ddPTM_PC-9_Lapatinib_30min_R1 2 FAGHSEAGGGSGDR 14 0 O96013 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 FAGHSEAGGGS(1)GDR;FAGHSEAGGGS(1)GDR 77.506 0.008527700000000001 8680800.0 31201.0 32377.0 37089.0 28120.0 34768.0 29715.0 31566.0 30385.0 29936.0 25221.0 True False 30756.068018437367 32302.033045736956 34039.685587680244 30188.038605570116 32723.014596517984 28444.15871904824 33200.3330263758 31796.798025896063 26564.292439944784 29580.416245129945 1.039744260647481 1.092007386848557 1.1507507299963862 1.0205413728936357 1.1062391524630906 0.9615875071984906 1.1223754510838513 1.074927335788624 0.8980364650655742 1.0 14.852354733222388 -8.246795156376203 24.45361180704836 0.9490182392327527 1.0719340470601795 0.4312749453777295 0.05603318306984892 466.4457334715713 778897.3086840699 0.03681290552251533 0.013766699601510373 5.665064300489098e-09 8.246795156376203 0.12291580782742673 FAHEHEEMK ddPTM_PC-9_AZD4547_30min_R2 2 FAHEHEEMK 9 0 P48163;P48163-2 P48163 ME1 NADP-dependent malic enzyme 0 ; 78.334 0.012126999999999999 7052200.0 27457.0 26328.7 34583.0 35368.0 37434.0 32454.0 31556.0 37218.0 33726.0 29616.0 False True 36187.75485892152 34838.93738920967 34124.40682386921 27214.454030152887 32236.935257874677 30424.646249575057 34364.42286792781 31466.813284557844 35508.6875070064 28579.152854408818 1.2662290951475474 1.2190332431017168 1.1940314325518906 0.9522484507778052 1.1279877826365166 1.0645748110368338 1.2024297236167556 1.1010407986849602 1.2424681615966298 1.0 14.802675532132339 -5.5370811059572 24.995904042503494 1.1044062283607072 1.2336065140888743 0.34894368998576863 0.08133444748570405 253.97696877835833 446993.3777711217 0.021787872934722036 0.03775643464505692 2.903480369091362e-06 5.5370811059572 0.1292002857281671 FAHEHEEMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FAHEHEEMK 9 0 P48163;P48163-2 P48163 ME1 NADP-dependent malic enzyme 0 62.2 0.034935 2037500.0 14120.0 12360.0 12283.0 16399.0 14165.0 14204.0 14847.0 11878.0 16848.0 11978.0 False True 16510.237117287837 13587.019115605706 12575.873303536904 15480.21719627534 11389.469934303319 13459.117235287064 13440.584677028479 11566.215085781296 17094.370126715483 14149.516582204169 1.1668410734295152 0.9602461707203541 0.8887846613327812 1.0940456591813739 0.8049370357025372 0.9512068597604656 0.9498970935821713 0.8174282858771381 1.2081239685753684 1.0 13.788465143817184 -4.762306155207921 6.739290517922093 0.953730370958798 1.1720132628308175 0.21586998875641183 0.11467506760958882 0.1613745601951508 38.217408570311804 0.026608871821341168 0.16194188269711154 1.728597357626516e-05 4.762306155207921 0.21828289187201955 FAHEHEEMK ddPTM_PC-9_Lapatinib_30min_R1 1 FAHEHEEMK 9 0 P48163;P48163-2 P48163 ME1 NADP-dependent malic enzyme 0 59.8 0.040527 2838700.0 19684.0 19113.0 19315.0 16844.0 20594.0 18169.0 17559.0 15527.0 21101.0 19806.0 False True 19403.302550396504 19068.745022799216 17726.99525805612 18082.7639499368 19382.70140936182 17391.954224007637 18468.119103153156 16248.4411041003 18724.38317661928 23229.440710163894 0.835289269013985 0.8208869623992199 0.7631262189752069 0.7784416411723939 0.834402414212282 0.7487030979785019 0.7950307256029866 0.6994762080944505 0.8060625914435618 1.0 14.503666798681685 -8.564010436352907 22.71635367052168 1.0000000004156573 0.7835062346568091 0.7269605008176455 0.039389510372428015 4167.593375836922 2301688.261881076 0.03847203471084203 0.009933436690965235 2.728912204648049e-09 8.564010436352907 -0.21649376575884816 FAIQDISVEETSAK ddPTM_PC-9_Lapatinib_30min_R1 4 FAIQDISVEETSAK 14 0 O43707;G3V2E8;P12814-4;P12814-3;P12814;P12814-2;H9KV75;P35609-2;P35609;A0A494C1A0;Q08043;G3V2N5;A0A087WSZ2;A0A494C033;G3V2W4;A0A494C166;G3V2X9;G3V5M4 O43707;P12814-4 ACTN4;ACTN1;ACTN2;ACTN3 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2;Alpha-actinin-3 0 ;;; 231.74 1.2996000000000001e-20 31042300.0 132785.0 119494.0 146971.0 134351.0 139767.0 129015.0 152363.0 134217.0 133127.0 143659.0 False True 130891.46155021312 119217.31898468961 134887.61170446663 144231.62072179778 131546.17985249453 123497.32919865409 160251.61062211552 140453.21180324795 118132.83537054138 168490.26673641495 0.7768488001445143 0.7075620526566819 0.8005661948145878 0.8560234577076952 0.7807345931636781 0.7329641740780937 0.9511030739408353 0.8335983705395399 0.7011255763239285 1.0 17.362305727347284 -14.522878745280336 0.21895886321870228 1.9931495197212936 0.7718933830408126 0.4114432533130544 0.07231287727103415 159.46253488890162 1.5908772612291837 70.15546226779446 0.14379232763205946 3.0000000000000132e-15 14.522878745280336 -1.221256136680481 FALGLSGGS(ph)LVSMLAR ddPTM_PC-9_AZD4547_30min_R2 1 FALGLSGGSLVSMLAR 16 0 M0R0U3;M0R261;O95336 M0R0U3 PGLS 6-phosphogluconolactonase 1 FALGLS(0.316)GGS(0.652)LVS(0.032)MLAR 70.373 0.017495 1589400.0 2424.6 1173.0 3953.9 3335.0 3204.7 3828.2 3088.9 2882.7 1234.6 3006.0 True False 3195.5723651870617 1552.149310734787 3901.4687025676353 2566.167275236368 2759.782722148606 3588.8220488267466 3363.806116007804 2437.2449528560096 1299.8584355141452 2900.7608549551896 1.1016324767787264 0.5350835137213558 1.344981161029872 0.8846531663762436 0.9513996017404331 1.2372002478922675 1.1596288988323953 0.840208853719401 0.4481094790332949 1.0 11.50221564617813 -7.990714543086094 11.360861877145473 0.6974034093667276 1.0213877248862793 0.210701290269522 0.24303023566706308 0.42111265413334953 502.3920786764325 0.13194550850274528 0.06174168828515645 1.0216107564170375e-08 7.990714543086094 0.32398431551955165 FALVT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 FALVTPK 7 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 FALVT(1)PK 93.598 0.033761 26461000.0 117080.0 99555.0 101480.0 101230.0 82872.0 86372.0 76836.0 73042.0 81646.0 65808.0 True False 115410.41773015758 99324.48651414113 93136.70612412799 108674.79189338058 77997.63189262085 82678.0709029659 80814.19211856459 76435.7979729308 72450.1677095046 77182.825116352 1.4952862577416417 1.2868729068210563 1.206702475372283 1.4080178035664654 1.0105568405281944 1.0711977797953094 1.0470488997615512 0.9903213293592833 0.938682506118259 1.0 16.235992231238377 -5.925515554062435 0.5392876196655683 0.9571337331891151 1.4908431615413704 0.7734173624064247 0.08731131802006355 0.701849550951509 0.350778532633877 0.06359586617664331 0.20682146342754218 1.1870921851071126e-06 5.925515554062435 0.5337094283522553 FAMEPEEFDSDTLR ddPTM_PC-9_AZD4547_30min_R2 1 FAMEPEEFDSDTLR 14 0 A0A499FI48;P13667 A0A499FI48 PDIA4 Protein disulfide-isomerase A4 0 169.82 0.0039094 3777200.0 6332.5 8012.7 6854.0 8607.5 10398.0 7377.4 7453.8 9664.7 7487.1 7861.3 False True 8346.103275817482 10602.648578111359 6763.1114816759555 6623.173859549341 8954.41718254477 6916.0900117586425 8117.1737600760625 8171.242687712033 7882.852820782407 7586.07827979349 1.100186811682186 1.3976455537445347 0.8915161737376723 0.873069538076219 1.1803750043544936 0.9116818673201081 1.070009227521052 1.0771366160928244 1.0391209436606283 1.0 12.889138543360833 -5.266040330117584 24.99984116864899 1.0086071565538246 1.2489161831348434 0.4319693191407854 0.11166557837314546 323.1165732769157 1755702.2783300623 0.02844231521245342 0.06254375141080869 5.419505606239435e-06 5.266040330117584 0.24030902658101883 FAMEPEEFDSDTLR ddPTM_PC-9_Lapatinib_30min_R1 2 FAMEPEEFDSDTLR 14 0 A0A499FI48;P13667 A0A499FI48 PDIA4 Protein disulfide-isomerase A4 0 ; 190.26 1.0398e-05 4555300.0 16683.8 13846.8 15669.7 13418.9 16920.7 16021.0 16976.9 14994.4 15645.9 13652.0 False True 16445.885952565794 13814.738585344858 14381.397752791201 14405.77067013815 15925.457693376156 15335.819176775092 17855.880813390333 15691.09456374842 13883.693983368923 16011.730009853443 1.0271148678153563 0.8627886291389761 0.8981788816037397 0.8997010729804336 0.9946119303520484 0.9577865207156002 1.1151749874874246 0.9799749654841977 0.867095184269598 1.0 13.966841573836858 -6.267067384220237 24.345567215826858 0.9898433655956907 0.9160227039963726 0.16638635422748016 0.0691275552304317 539.2209733716202 2332552.405349624 0.021634421311829733 0.02523903033251658 5.406704271485811e-07 6.267067384220237 -0.0738206615993181 FANLT(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 2 FANLTPSR 8 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0;X6RGP5;A0A0C4DH09 O15027 SEC16A Protein transport protein Sec16A 1 FANLT(1)PSR;FANLT(0.999)PS(0.001)R 105.17 0.009404899999999999 42160000.0 107219.0 98077.0 119583.0 164879.0 140395.0 123917.0 109794.0 164148.0 113415.0 117948.0 True False 141312.41170625706 129778.47224973193 117997.25128585596 126868.69390515669 120903.57764410188 116168.45040083148 119565.45330083893 138782.6983457895 119409.88535868847 113818.67642057707 1.2415573274115972 1.140221239001067 1.036712558928716 1.1146562048952129 1.062247264212993 1.0206448893463815 1.0504906317749352 1.219331507888623 1.0491238267211176 1.0 16.796377782244626 -4.883344534868454 2.9291608008780075 1.0760615105171192 1.252439762724081 0.45137956917796684 0.05853587008827521 0.3097037160586868 4.370425507479352 0.015223807693900922 0.11618540516079977 1.3081437335437967e-05 4.883344534868454 0.1763782522069619 FANLT(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FANLTPSR 8 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0;X6RGP5;A0A0C4DH09 O15027 SEC16A Protein transport protein Sec16A 1 FANLT(0.989)PS(0.011)R;FANLT(0.958)PS(0.042)R 104.42 0.0094339 19841300.0 52825.0 55290.0 58362.0 66374.0 69276.0 76159.0 76075.0 74512.0 65494.0 51987.0 True False 61767.22915869197 60778.825801119725 59753.57141911753 62655.27996741145 55701.865101927 72165.08796974282 68868.6252646961 72556.13895199003 66451.7258475252 61411.83157113443 1.005787119166864 0.9896924460023394 0.9729977089171146 1.0202477008821453 0.9070217200313676 1.175100727718122 1.1214227536093646 1.1814684091932177 1.0820671546093357 1.0 15.90622901079002 -6.767230462485539 24.999999853491484 1.1239417744369407 0.9816765497648035 0.5845996382363428 0.05552473074533121 90.17625204999374 389286.83507044957 0.018119344317534078 0.01640700108020096 1.7091081199732027e-07 6.767230462485539 -0.1422652246721372 FANLT(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 2 FANLTPSR 8 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0;X6RGP5;A0A0C4DH09 O15027 SEC16A Protein transport protein Sec16A 1 FANLT(0.91)PS(0.09)R;FANLT(1)PSR 109.83 0.0092221 26935100.0 57326.0 58508.0 75913.0 59706.0 64229.0 80697.0 84244.0 64138.0 82115.0 54284.0 True False 56508.5207276991 58372.52832072079 69671.72617265403 64096.978413377314 60451.176499072564 77245.77742389477 88605.74211094232 67118.08562728055 72866.34399071566 63666.917071116666 0.8875648975523417 0.9168423885754986 1.0943160023726282 1.006754863625331 0.9494911844333206 1.2132796902606477 1.3917077532114317 1.0542066227631046 1.1444930482392155 1.0 15.958256286163294 -6.7601666872565875 24.999993664176564 1.178560998600668 0.9768233842368037 0.41941849682106513 0.1105250537416227 33.52980396180827 658645.3273264084 0.038628897972455035 0.0366180329650713 1.737133968628857e-07 6.7601666872565875 -0.20173761436386428 FAPQS(ph)RRSS(ph)GELS(ph)SPLRK ddPTM_PC-9_Lapatinib_30min_R1 1 FAPQSRRSSGELSSPLRK 18 3 A0A0A0MR54;Q14162-2;Q14162 A0A0A0MR54 SCARF1 Scavenger receptor class F member 1 3 FAPQS(0.827)RRS(0.197)S(0.972)GELS(0.873)S(0.131)PLRK 48.547 0.037194 2956700.0 18230.0 22481.0 19694.0 25291.0 22425.0 20520.0 24263.0 22976.0 16884.0 20583.0 True False 17970.03685702743 22428.946625728524 18074.83534103843 27150.984508302776 21106.00558924632 19642.407434456327 25519.219420229216 24043.548838011768 14982.346123597943 24140.744124876484 0.7443862030130927 0.9290909389415221 0.7487273485663901 1.1246954264481146 0.8742897683711855 0.8136620533670822 1.0571016074824406 0.9959738073374234 0.6206248674894399 1.0 14.559182526591979 -4.001471112872896 1.2862065129192546 0.914945381071762 2.1748710444766014e-16 0.09717179499441464 0.14336425758638285 21.95527962751364 7.214919039405633 0.040659769944250704 43.01810702552473 9.966183680689402e-05 4.001471112872896 -0.9149453810717618 FAQPGSFEYEYAMR ddPTM_PC-9_Lapatinib_30min_R1 1 FAQPGSFEYEYAMR 14 0 Q15233;Q15233-2;H7C367;C9JYS8 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 103.46 0.008426000000000001 0.0 14710.0 12766.0 11339.0 10249.0 14898.0 11537.0 12653.0 11590.0 12906.0 11839.0 False True 14500.232702516383 12736.4411113407 10406.751189805766 11002.745649661738 14021.72893059494 11043.589404060554 13308.110428395516 12128.513711375186 11452.390373795015 13885.355375524106 1.0442824335685443 0.9172571221181266 0.7494767622692523 0.7923992834246373 1.0098213946552077 0.7953407820967427 0.9584277872969598 0.8734752106348155 0.8247819421303606 1.0 13.761276480865037 FAQSAPGS(ph)PLSSQPVLITVQR ddPTM_PC-9_AZD4547_30min_R2 2 FAQSAPGSPLSSQPVLITVQR 21 0 Q01167-2;Q01167 Q01167-2 FOXK2 Forkhead box protein K2 1 FAQSAPGS(0.999)PLS(0.001)SQPVLITVQR;FAQSAPGS(0.983)PLS(0.013)S(0.004)QPVLITVQR 200.2 2.566e-19 116893000.0 142604.0 137599.0 183262.0 277291.0 233581.0 195834.0 177495.0 241135.0 161862.0 185111.0 True False 187949.105652535 182075.1858548983 180831.82613873624 213365.84405324364 201152.31005154716 183588.469021978 193291.71114662357 203873.1264810543 170417.6948721777 178630.3202334031 1.0521679936919766 1.0192848874535636 1.0123243685755956 1.1944548034983882 1.126081562126274 1.0277564793149139 1.0820767207608626 1.1413131108686827 0.9540244604023854 1.0 17.446617454883416 -10.233998397917265 11.328657146723144 0.9999818380308169 1.0715219144904766 0.08092302309065946 0.06737964190072654 0.0 0.0 0.06609789765301805 0.016031094920862302 5.834472565669269e-11 10.233998397917265 0.07154007645965976 FAQSAPGS(ph)PLSSQPVLITVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FAQSAPGSPLSSQPVLITVQR 21 0 Q01167-2;Q01167 Q01167-2 FOXK2 Forkhead box protein K2 1 FAQSAPGS(0.931)PLS(0.061)S(0.008)QPVLITVQR;FAQSAPGS(0.993)PLS(0.003)S(0.003)QPVLITVQR;FAQSAPGS(0.875)PLS(0.093)S(0.03)QPVLIT(0.002)VQR 231.93 5.4844e-42 62346200.0 187194.0 205787.0 211263.0 239730.0 303668.0 264279.0 263591.0 240141.0 251301.0 224482.0 True False 218882.24694997014 226216.17336109615 216300.3111393896 226298.70531514613 244166.4352989779 250419.7440034095 238621.75224642057 233837.5532004213 254975.80171021709 265178.8096014661 0.8254137925987582 0.8530703252687256 0.8156772083880481 0.8533815566004221 0.9207614879406563 0.9443429675989653 0.8998522642327348 0.881810856424964 0.9615240452033743 1.0 18.016605968950962 -1.522878748754476 0.09282444843099479 1.073054945195085 0.3424674419134143 0.7608676776906477 0.028247546564373748 78.90219269032899 0.5265533243917558 0.5214412083460528 7.3350147942822925 0.029999999760015026 1.522878748754476 -0.7305875032816707 FAQSAPGS(ph)PLSSQPVLITVQR ddPTM_PC-9_Lapatinib_30min_R1 2 FAQSAPGSPLSSQPVLITVQR 21 0 Q01167-2;Q01167 Q01167-2 FOXK2 Forkhead box protein K2 1 FAQSAPGS(0.998)PLS(0.002)SQPVLITVQR;FAQSAPGS(0.997)PLS(0.003)SQPVLITVQR 288.64 2.5704999999999995e-116 73582000.0 159064.0 141827.0 161549.0 126765.0 160421.0 175869.0 149919.0 152269.0 169432.0 134791.0 True False 156795.71819123506 141498.60829532475 148267.0648171738 136087.72097564355 150985.35217982103 168347.49284066274 157681.07226069915 159343.97362531399 150348.78396194289 158089.44475228197 0.99181648994293 0.8950541164658133 0.9378682115652989 0.8608273701567237 0.9550628279858109 1.0648876217160141 0.9974168263275089 1.0079355637879417 0.9510361947157934 1.0 17.270381520109723 -6.528564385225017 24.98976275158417 1.0049517600930307 0.9190944405759347 0.48684708687769174 0.040253364527288844 121.91049830377376 535820.9936065698 0.012898745008131625 0.012936726608580872 2.9609809601439854e-07 6.528564385225017 -0.08585731951709596 FAS(ph)DDEHDEHDENGATGPVK ddPTM_PC-9_AZD4547_30min_R2 4 FASDDEHDEHDENGATGPVK 20 0 P05455 P05455 SSB Lupus La protein 1 FAS(1)DDEHDEHDENGATGPVK;FAS(1)DDEHDEHDENGATGPVK;FAS(1)DDEHDEHDENGATGPVK;FAS(1)DDEHDEHDENGATGPVK 124.66 4.759e-06 84319000.0 246696.0 328178.0 293872.0 258239.0 291214.0 341171.0 335118.0 358120.0 321676.0 300510.0 True False 325140.19640443317 434255.12062942947 289975.0652674465 198705.9883027782 250783.96281954128 319837.5234366729 364942.8527904125 302780.78277892066 338679.13664543047 289989.2363681259 1.1212147060233815 1.497487031132996 0.999951132321817 0.6852184956635132 0.8648043836398962 1.1029289481305307 1.2584703396616315 1.0441104179279144 1.1679024397150222 1.0 18.14563982665456 -5.285789423665137 24.31905540306747 1.0116317903192475 1.3093508622426913 0.3196943145374399 0.1714368501785098 596.9589951733728 596198.5462564749 0.048953170431372234 0.10198900803520507 5.178578647929525e-06 5.285789423665137 0.2977190719234437 FAS(ph)DDEHDEHDENGATGPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 FASDDEHDEHDENGATGPVK 20 0 P05455 P05455 SSB Lupus La protein 1 FAS(1)DDEHDEHDENGATGPVK;FAS(1)DDEHDEHDENGATGPVK;FAS(1)DDEHDEHDENGATGPVK;FAS(1)DDEHDEHDENGATGPVK;FAS(0.998)DDEHDEHDENGAT(0.002)GPVK;FAS(1)DDEHDEHDENGATGPVK;FAS(0.999)DDEHDEHDENGAT(0.001)GPVK 89.721 0.00044199 53383000.0 297952.0 454573.0 374829.0 375336.0 418492.0 275097.0 358777.0 281552.0 256393.0 248073.0 True False 348389.38877975545 499700.0032717008 383766.34490689833 354307.1407757297 336491.4967699587 260670.4290394091 324791.0452394584 274161.55832900276 260142.26257709862 293046.6711552121 1.1888529134501962 1.7051891471820706 1.3095741486980979 1.209046802610056 1.1482522406532851 0.8895184784451794 1.1083253188275697 0.9355559551256365 0.8877161496208034 1.0 18.160770923665098 -6.0925993534656495 1.2755226541175186 0.9674854333403221 1.4520300872351073 0.650549986137863 0.13789894961344779 0.25962286949886254 0.8584466300746451 0.05028127852042704 0.08538641325360649 8.079800665224067e-07 6.0925993534656495 0.4845446538947852 FAS(ph)DDEHDEHDENGATGPVK ddPTM_PC-9_Lapatinib_30min_R1 5 FASDDEHDEHDENGATGPVK 20 0 P05455 P05455 SSB Lupus La protein 1 FAS(1)DDEHDEHDENGATGPVK;FAS(1)DDEHDEHDENGATGPVK;FAS(1)DDEHDEHDENGATGPVK;FAS(1)DDEHDEHDENGATGPVK;FAS(1)DDEHDEHDENGATGPVK 132.24 1.5226e-05 250990000.0 325380.0 529034.0 540747.0 541849.0 629149.0 529013.0 635493.0 689841.0 556546.0 584895.0 True False 320740.0215326164 527809.0542767531 496288.8690037835 581698.3830152771 592143.6927745261 506388.3471795343 668395.7180488695 721893.5312483852 493861.92879080464 685993.3214264009 0.4675556036984364 0.7694084443552135 0.723460205081646 0.8479650819423998 0.863191629246869 0.7381826198053794 0.9743472671994236 1.0523331768702007 0.7199223569172755 1.0 19.387835005365638 -4.202955885683025 0.5325567992395217 0.9141998144050928 5.869055073499626e-23 0.579455027929771 0.10565983086687443 5.6051581333242355 0.769426810574763 0.05802615595129752 3.632705197752153 6.266775174419986e-05 4.202955885683025 -0.9141998144050928 FAS(ph)DDEHDEHDENGATGPVKR ddPTM_PC-9_AZD4547_30min_R2 3 FASDDEHDEHDENGATGPVKR 21 1 P05455 P05455 SSB Lupus La protein 1 FAS(1)DDEHDEHDENGATGPVKR;FAS(1)DDEHDEHDENGATGPVKR;FAS(1)DDEHDEHDENGATGPVKR 86.211 0.00020780000000000004 99365500.0 263365.7 243883.8 335245.0 401241.0 337121.0 349502.0 264086.1 322503.0 274513.0 349529.0 True False 347110.5142531336 322714.4689423533 330799.43225480826 308741.0865616542 290317.5682820429 327647.5846896828 287589.2512974357 272667.5717316821 289023.1967506032 337292.09609834716 1.0291095411613904 0.9567804068799071 0.9807506196598044 0.915352272208691 0.8607304222076776 0.971406055700006 0.8526415371843782 0.8084019011586269 0.8568928833313966 1.0 18.3636389859345 -5.462066013230232 0.7390938625516337 0.876248890480735 1.0376484748559294 0.3635982202380237 0.05663245212764571 1.374739993921855 1.0496699886420433 0.026437357414402743 0.1592280394791378 3.45091281101721e-06 5.462066013230232 0.16139958437519442 FAS(ph)DDEHDEHDENGATGPVKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 FASDDEHDEHDENGATGPVKR 21 1 P05455 P05455 SSB Lupus La protein 1 FAS(1)DDEHDEHDENGATGPVKR;FAS(1)DDEHDEHDENGATGPVKR;FAS(1)DDEHDEHDENGATGPVKR;FAS(1)DDEHDEHDENGATGPVKR 88.41799999999999 0.00020017 86584000.0 267607.4 224170.3 304935.3 330379.1 330532.0 317184.9 337334.0 291893.0 317850.0 261617.4 True False 312908.0473329245 246424.44589409934 312206.1140255655 311869.03013049427 265766.6273438155 300551.16547189595 305379.2814333353 284231.11803619826 322497.9549368783 309046.56365780154 1.0124948280589803 0.7973699593274174 1.0102235414960397 1.0091328194667066 0.8599565845297388 0.972510944352993 0.9881335609072588 0.9197032145321612 1.0435254516985055 1.0 18.23746469799427 -8.262977271447872 24.969403327560737 1.0217627308514505 0.9448634584874955 0.1650435521696899 0.06793891419691657 239.32292350224233 3885484.950874753 0.05335403646492607 0.016647230571318828 5.45786423762692e-09 8.262977271447872 -0.076899272363955 FAS(ph)DDEHDEHDENGATGPVKR ddPTM_PC-9_Lapatinib_30min_R1 6 FASDDEHDEHDENGATGPVKR 21 1 P05455 P05455 SSB Lupus La protein 1 FAS(1)DDEHDEHDENGATGPVKR;FAS(0.999)DDEHDEHDENGAT(0.001)GPVKR;FAS(1)DDEHDEHDENGATGPVKR;FAS(1)DDEHDEHDENGATGPVKR;FAS(1)DDEHDEHDENGATGPVKR;FAS(1)DDEHDEHDENGATGPVKR 69.289 0.0011355 447144100.0 597473.0 536493.0 573345.0 513571.0 517055.0 501202.0 467261.0 466065.0 500879.0 411981.0 True False 588952.925456871 535250.7834205306 526206.7872757021 551340.7245626323 486642.84146924235 479766.7588189271 491453.48825436784 487720.08135393355 444464.7325303011 483191.3669198232 1.2188813082717949 1.1077407836000217 1.0890235697506088 1.1410400977923871 1.007143079917634 0.9929125221695768 1.01709906654006 1.0093725069282162 0.919852387602885 1.0 18.88223515299628 -5.1814990922089414 0.42365634335358665 0.9666391556545612 1.301297935512456 0.783262726628126 0.038652540422676934 1.8360172206402645 0.3323203474563306 0.03210363223666493 0.30044846935205805 6.5841680620831236e-06 5.1814990922089414 0.33465877985789494 FATHAAALSVR ddPTM_PC-9_Lapatinib_30min_R1 1 FATHAAALSVR 11 0 P23246;P23246-2 P23246 SFPQ Splicing factor, proline- and glutamine-rich 0 111.52 0.001286 0.0 23170.0 20576.0 24372.0 18562.0 25975.0 26327.0 22732.0 19355.0 22894.0 24133.0 False True 22839.5915511424 20528.35753618567 22368.228238640633 19927.111401016806 24447.201568814864 25201.055581234494 23908.95173146975 20254.30395890136 20315.436635492246 28304.356894798802 0.8069284752178698 0.7252720000841267 0.79027509163266 0.7040298239271638 0.8637257387503926 0.8903595893346522 0.8447092375330828 0.7155896187354563 0.7177494514713882 1.0 14.788736524010066 -6.269698778868575 24.87679908420725 0.8273529667653133 0.756790232393312 0.1860890893386553 0.0820470417962103 1205.269074802607 3630190.4287058837 0.025975660801159414 0.029931869835485646 5.374044039999039e-07 6.269698778868575 -0.07056273437200133 FAVLHGEAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FAVLHGEAPR 10 0 P55884;P55884-2 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 0 ; 111.06 0.0013851 4437700.0 63428.0 69120.0 79949.0 78549.0 80900.0 67847.0 76930.0 74963.0 69925.0 51544.0 False True 74165.1076398961 75981.77680183384 81855.28736827112 74148.15418929406 65048.22574550924 64288.98388218267 69642.63347503211 72995.30067986394 70947.52083989677 60888.51917792052 1.2180474848333962 1.247883473398487 1.344346823891122 1.2177690505598922 1.0683167635500177 1.0558473871621965 1.143772823108597 1.1988352100757542 1.1652035851386555 1.0 15.89388260626023 -6.0728150903151885 5.100637061537175 1.1156266728350863 1.2701039339623623 0.5964327592221148 0.06182249116973179 0.16547776560990723 7.9503815566093206 0.019317206200275307 0.025609089074173436 8.456388164011723e-07 6.0728150903151885 0.154477261127276 FAVLHGEAPR ddPTM_PC-9_Lapatinib_30min_R1 1 FAVLHGEAPR 10 0 P55884;P55884-2 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 0 107.24 0.0018465 3670300.0 45089.0 43268.0 53473.0 46538.0 55605.0 46500.0 50040.0 51478.0 52812.0 46546.0 False True 44446.02259169007 43167.815604377996 49076.65635174918 49960.559766217 52334.4232236362 44511.30339679428 52630.82635239957 53869.855809678374 46863.75642498541 54591.41408135357 0.8141577451255508 0.7907436788511867 0.8989812258501648 0.9151724791697912 0.9586566698134263 0.8153535523088367 0.9640861523383094 0.9867825685812075 0.8584455488760155 1.0 15.736386447246232 -2.1948220419827194 0.30152507042032284 0.9551574840505525 1.365478621328746e-17 0.4329896687434215 0.055080951639946064 35.09558194094515 0.7248204190104911 0.05648167767293538 16.788852328421292 0.006385250768478718 2.1948220419827194 -0.9551574840505525 FAYLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FAYLGR 6 0 P40429;M0QYS1;Q8J015 P40429 RPL13A;RPL13a 60S ribosomal protein L13a 0 106.05 0.046327 0.0 14355.0 15958.0 18549.0 17812.0 19958.0 14346.0 21377.0 24843.0 19763.0 16113.0 False True 16785.01797582628 17542.2047772521 18991.278507474224 16814.051387283158 16047.373169701763 13593.67050531036 19352.01580392252 24190.897573334296 20051.996487077286 19034.15934956218 0.8818365795709473 0.9216169968470713 0.9977471638594356 0.8833619115240786 0.843082842535459 0.7141723601059923 1.0166992641241943 1.2709201982114715 1.0534742364410499 1.0 14.216303233715488 -7.518903538190153 24.95024911164036 1.1260803112121158 0.879255580038021 0.5653815515946088 0.09304068188919795 117.0622556861523 734752.6676650214 0.04332790273378197 0.02575888612241846 3.027585815129757e-08 7.518903538190153 -0.24682473117409487 FCDS(ph)PTSDLEMR ddPTM_PC-9_Lapatinib_30min_R1 2 FCDSPTSDLEMR 12 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 FCDS(0.974)PT(0.011)S(0.015)DLEMR;FCDS(0.486)PT(0.35)S(0.164)DLEMR 123.95 0.00033685 5503700.0 20554.0 24622.0 27696.0 20424.0 25226.0 20746.3 22760.0 23955.0 26503.0 18663.0 True False 20260.896190858024 24564.989271771177 25418.941789651686 21926.049092466717 23742.256276224187 19859.029110987376 23938.401434464693 25068.03675202697 23517.95305103744 21888.874683115664 0.9256252998006606 1.1222591214668416 1.161272205978638 1.0016983243720485 1.0846723104746065 0.9072658781452094 1.0936332626057732 1.1452410009621738 1.0744249483587383 1.0 14.417910166374389 -10.572809700875831 4.794041032182917 0.9999983071132381 1.0607152694270146 0.0402269835606156 0.08256418550041178 1.502647403190389e-06 2.9767800330827966e-07 0.08040897179532469 0.019501496521242175 2.67417792306335e-11 10.572809700875831 0.060716962313776435 FCDSPT(ph)SDLEMR ddPTM_PC-9_Lapatinib_30min_R1 1 FCDSPTSDLEMR 12 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 FCDS(0.198)PT(0.401)S(0.401)DLEMR 87.667 0.032293999999999996 3669400.0 21789.0 23154.0 27735.0 23180.0 30609.0 26172.0 23839.0 21905.0 29084.0 22594.0 True False 21478.28486438678 23100.38833557753 25454.735360196035 24884.73452621319 28808.638799609376 25052.684569911828 25073.26677487716 22922.786268134045 25808.25365190253 26499.342795387423 0.8105214167094503 0.8717343865448041 0.9605798738762225 0.9390698749911911 1.0871454066635915 0.9454077696701442 0.946184475912418 0.8650322555216 0.9739205176210941 1.0 14.693668959693486 -5.050277906097645 2.148340956810611 0.9631069114266138 0.8036229490510277 0.48514043908825644 0.05269835520639841 0.3754226966937155 2.8582594787928373 0.015194243063349 0.09316676662891595 8.906808069194715e-06 5.050277906097645 -0.15948396237558604 FCFTPHTEEGCLSER ddPTM_PC-9_Lapatinib_30min_R1 2 FCFTPHTEEGCLSER 15 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 ; 98.0 0.0019649999999999997 7949100.0 33173.0 35247.0 39370.0 40513.0 42388.0 41014.0 34665.0 32680.0 39387.0 31760.0 False True 32699.946936816872 35165.38773706923 36133.150572594874 43492.46116740617 39894.821178014376 39259.92682830366 36459.78408285233 34198.43210420547 34950.821296502705 37249.67368246015 0.8778586146974593 0.9440455247163051 0.970025962659882 1.1675930784834117 1.0710112930948912 1.05396700016704 0.9787947243151354 0.9180867568326802 0.9382853013544677 1.0 15.184940166768314 -10.65045856916193 14.325961878691219 1.000009307906618 0.9959567385068577 0.0 0.08090489444420869 0.0 0.0 0.08718315265686284 0.021145020422270268 2.2363585327452234e-11 10.65045856916193 -0.004052569399760175 FCLDNGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FCLDNGAK 8 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 101.54 0.020983 2864300.0 23323.0 32832.0 26291.0 37065.0 44864.0 29385.0 29919.0 32793.0 31668.0 22902.0 False True 27271.123249752418 36091.343980871075 26917.877149172728 34988.368216351315 36073.22125891874 27843.998870663938 27084.85572519803 31932.21849705556 32131.08459003004 27053.951307867763 1.0080273650016327 1.3340507480833337 0.9949702667404645 1.2932812592952396 1.3333808746978861 1.0292026681724091 1.0011423254584362 1.1803162552365913 1.1876669778985578 1.0 14.723551698775513 -6.79487166855652 24.999980278912815 1.086027715554303 1.1951910705047535 0.16535628072958264 0.126560297447554 375.84143713617783 281044.0030307416 0.04436548935892917 0.03912889562018354 1.6037192101956713e-07 6.79487166855652 0.10916335495045049 FCYHER ddPTM_PC-9_AZD4547_30min_R2 1 FCYHER 6 0 F8WDL5;C9JPQ5;P28331-4;P28331;P28331-2 F8WDL5 NDUFS1 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 0 74.335 0.032305 0.0 5830.3 4824.1 8131.5 10284.0 7624.3 6824.0 5675.4 8851.6 5845.5 6858.4 False True 7684.214122226395 6383.395984582851 8023.670996972282 7913.182686216139 6565.797549997698 6397.294201241764 6180.499605293365 7483.788609532822 6154.481196175227 6618.289503534493 1.1610574179510653 0.9645084248994855 1.2123481441371289 1.1956537534343443 0.9920686525561082 0.9666083959949612 0.9338515037749064 1.1307738359792376 0.9299202147153627 1.0 12.692242685435906 -6.281464314802419 23.822570070500383 0.9945450547633767 1.1269685511217045 0.416317434699217 0.08172966654572936 480.88794494826146 572084.3301881151 0.025687862604825536 0.02917239722222263 5.230409417513156e-07 6.281464314802419 0.13242349635832773 FCYHER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FCYHER 6 0 F8WDL5;C9JPQ5;P28331-4;P28331;P28331-2 F8WDL5 NDUFS1 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 0 95.95700000000001 0.02053 0.0 6673.6 5317.2 6379.3 5835.5 8328.8 7059.6 5643.6 5981.9 7216.4 5443.2 False True 7803.3086703917925 5845.05647584941 6531.4067056299755 5508.555853946261 6696.8314287910625 6689.382148284467 5108.997351874315 5824.881463346953 7321.92619791249 6430.009071652507 1.2135766191674047 0.9090277184239236 1.0157694387126905 0.8566948806077759 1.041496420015156 1.0403379021307197 0.7945552323398678 0.9058900848253334 1.1387116435328388 1.0 12.65060505761482 -4.7540702036729545 24.79255820538907 0.9613185568668591 1.2135771149525845 0.36891172503797076 0.09652191195138633 254.72918066720104 856919.9988780539 0.02373128510687768 0.23845324348196728 1.7616912461252164e-05 4.7540702036729545 0.2522585580857254 FDADYAEK ddPTM_PC-9_AZD4547_30min_R2 1 FDADYAEK 8 0 A0A0A6YYL2;P50225-2;P50225;P0DMN0;P0DMM9;P0DMM9-3 A0A0A6YYL2 SULT1A4;SULT1A1;SULT1A3 Sulfotransferase;Sulfotransferase 1A1;Sulfotransferase 1A4;Sulfotransferase 1A3 0 128.69 0.00010511 0.0 23187.0 35001.0 32781.0 36741.0 31733.0 31988.0 28311.0 29013.0 28052.0 33299.0 False True 30559.98368043899 46314.388768140016 32346.30252127508 28270.930092791452 27327.42070145154 29987.785303241733 30830.624154325775 24529.707502414883 29534.77145070696 32133.212145426784 0.9510404232895311 1.441324588358388 1.006631468241765 0.879804047128696 0.8504416109343366 0.9332333526920561 0.9594628764405555 0.7633755191170941 0.9191353580538436 1.0 14.971777584281824 -5.498385480414208 10.061306189172388 0.8964158279121003 1.20337371672152 0.465974222571379 0.12528390089601785 0.36522377313965065 145.77222909711193 0.03064795705085378 0.061362772684079865 3.1740555236593033e-06 5.498385480414208 0.30695788880941965 FDASFFGVHPK ddPTM_PC-9_Lapatinib_30min_R1 2 FDASFFGVHPK 11 0 P49327;A0A0U1RQF0;A0A0U1RRG3 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 ; 115.57 0.0011297 4212800.0 48320.0 45957.0 53833.0 48374.0 51369.0 54476.0 50532.0 49391.0 52522.0 41112.0 False True 47630.94793919728 45850.58939008969 49407.05854138935 51931.58533093348 48347.576415339776 52146.18846975839 53148.299705025056 51685.88617071025 46606.419278820824 48218.154421703446 0.9878218797556909 0.9508988873587395 1.024656773655998 1.0770131282245547 1.0026840926449494 1.081463799167869 1.1022466608780552 1.0719175545102562 0.9665741013480772 1.0 15.557288811543149 -5.4249146545721025 4.541747057297555 1.0487088581722062 0.9703962117232466 0.32184735566192946 0.04154261371595472 0.2354947853517597 8.039163301363324 0.0111232801187559 0.023992664739431294 3.7591126927485726e-06 5.4249146545721025 -0.07831264644895952 FDDDVVSR ddPTM_PC-9_AZD4547_30min_R2 1 FDDDVVSR 8 0 H3BND8;A0A669KBL1;Q93009-3;Q93009;F5H2X1 H3BND8 USP7 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 7 0 124.08 0.015285 3007600.0 32681.0 27262.0 38010.0 51832.0 37062.0 37935.0 30849.0 44911.0 30891.0 39839.0 False True 43072.87819297136 36073.90836253346 37505.96256470717 39882.933196417245 31916.58103668726 35562.91845312224 33594.50123756829 37971.03690211131 32523.835194773597 38444.24873604783 1.120398488957424 0.9383434336358409 0.9755935880609142 1.0374226186665056 0.8302043110744988 0.9250517209294854 0.8738498564043443 0.9876909589992114 0.8460000198749398 1.0 15.230480166537808 -1.522878746778751 0.767595192029762 0.92084201429942 37.12955497227985 0.4091284493688385 0.0656126155395332 412.384130508884 1.6524535246168497 0.023354706898880154 25875.185655843492 0.029999999896493264 1.522878746778751 36.20871295798043 FDDDVVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FDDDVVSR 8 0 H3BND8;A0A669KBL1;Q93009-3;Q93009;F5H2X1 H3BND8 USP7 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 7 0 95.815 0.029077 2139600.0 12845.0 18697.0 18291.0 19002.0 23093.0 17313.0 23123.0 17077.0 13032.0 13580.0 False True 15019.40479968571 20553.11459583172 18727.12680900378 17937.3795453152 18568.09242448757 16405.075802205363 20932.622043977208 16628.74684457714 13222.568345878217 16041.94650077915 0.9362582526351291 1.2812107679597027 1.1673849434726773 1.1181548039973823 1.157471284646519 1.0226362369060749 1.3048679624358877 1.036579123597594 0.8242496224031169 1.0 13.969561585970892 -8.001568413110196 24.989261663340958 0.918221295239576 1.1447235054460616 0.41273963004367387 0.10933364399617498 48.819345751942 777820.4011507286 0.057072952307868574 0.026789714587325892 9.963951086315159e-09 8.001568413110196 0.22650221020648564 FDDDVVSR ddPTM_PC-9_Lapatinib_30min_R1 1 FDDDVVSR 8 0 H3BND8;A0A669KBL1;Q93009-3;Q93009;F5H2X1 H3BND8 USP7 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 7 0 124.08 0.0010282 0.0 29204.0 38485.0 37299.0 39490.0 36111.0 39143.0 38444.0 33031.0 35482.0 32379.0 False True 28787.545604642306 38395.89034701134 34232.4201983037 42394.226334778235 33987.0219769576 37468.945136789654 40434.442212063346 34565.74084559395 31485.643517975695 37975.66700769447 0.7580524023135523 1.0110655946933524 0.9014303867623357 1.1163523823344168 0.8949684009518856 0.9866566696299989 1.0647460702631157 0.9102076031631092 0.829100474037657 1.0 15.212787684112019 -4.754463565109254 24.938595804681384 0.969310761088174 0.7580520266630425 0.3724574622690413 0.08185472836368608 256.62108498778315 917339.5802374337 0.020037350973064465 0.19482600924434038 1.7600963198962068e-05 4.754463565109254 -0.21125873442513154 FDDGAGGDNEVQR ddPTM_PC-9_Lapatinib_30min_R1 1 FDDGAGGDNEVQR 13 0 P35998;P35998-2 P35998 PSMC2 26S protease regulatory subunit 7 0 122.55 0.00083015 6519400.0 34353.0 43140.0 39071.0 39807.0 39262.0 34033.0 38354.0 34964.0 39012.0 36057.0 False True 33863.11992043137 43040.11198051371 35858.7331984215 42734.539572259244 36952.68635206194 32577.48792479784 40339.78245243669 36588.55508235738 34618.057745427795 42289.40440706753 0.800747146837851 1.0177516705182237 0.8479365860359264 1.0105259265632345 0.8738048423752758 0.7703463404500772 0.9538980985434494 0.8651943813198417 0.818598848359338 1.0 15.368008621518888 -6.469294764835124 24.99769574797099 0.8715195297134372 0.9238064493459796 0.04036397066517283 0.08579969726105244 859.0394173113823 400753.6776596513 0.025060735126082503 0.02841600248726431 3.393948399552071e-07 6.469294764835124 0.052286919632542395 FDGSENRPFS(ph)PSPLNNISSTVTVK ddPTM_PC-9_AZD4547_30min_R2 1 FDGSENRPFSPSPLNNISSTVTVK 24 1 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 FDGS(0.285)ENRPFS(0.638)PS(0.075)PLNNIS(0.001)STVTVK 43.956 0.028932999999999997 26306000.0 18888.0 13544.0 22853.0 24639.0 27398.0 17818.0 19568.0 21372.0 19079.0 20454.0 True False 24893.99110519395 17921.833132644457 22549.95428811505 18958.8592187553 23594.26062390474 16703.83764327752 21309.514091761048 18069.44847970257 20087.47698944953 19737.911685713076 1.2612272008093444 0.9079903395057161 1.1424691044918098 0.9605301472940687 1.1953777582753606 0.8462819121522508 1.0796235402748078 0.9154691117997963 1.0177103489620678 1.0 14.268681737122868 -6.7580774889316295 24.999992695039793 0.9732717226810137 1.078542935243098 0.21956364120771188 0.11295715537036168 150.48530519214805 1119054.2187911444 0.035085987651150376 0.03371781089547792 1.7455106826371526e-07 6.7580774889316295 0.10527121256208427 FDGSENRPFS(ph)PSPLNNISSTVTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FDGSENRPFSPSPLNNISSTVTVK 24 1 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 FDGS(0.001)ENRPFS(0.942)PS(0.057)PLNNISSTVTVK 82.36200000000001 3.3294000000000003e-05 23241000.0 11863.0 14035.0 11824.0 13012.0 14810.0 14583.0 16706.0 12415.0 16150.0 11278.0 True False 13871.171595069796 15428.302045916358 12105.92900276971 12282.97982547318 11908.086814474562 13818.2418080957 15123.486739033991 12089.119404779834 16386.16319720175 13322.612123401124 1.0411750688669477 1.1580538338136106 0.9086753326328315 0.9219648302976686 0.8938252276787407 1.0372021402487581 1.135174288566852 0.9074135982346387 1.229951232192635 1.0 13.70158935445217 -6.988176622998061 24.67681524673665 1.0641005412559432 0.9845402045367128 0.1218673605466305 0.10603417252132802 455.2733157506213 950206.1490108985 0.03800687664643528 0.03349320855198867 1.0275982997138137e-07 6.988176622998061 -0.07956033671923046 FDGSENRPFS(ph)PSPLNNISSTVTVK ddPTM_PC-9_Lapatinib_30min_R1 1 FDGSENRPFSPSPLNNISSTVTVK 24 1 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 FDGS(0.001)ENRPFS(0.972)PS(0.026)PLNNIS(0.001)STVTVK 70.572 0.00033685 19680000.0 51992.0 63473.0 63331.0 49478.0 48931.0 54547.0 58557.0 53990.0 62674.0 39423.0 True False 51250.58454583494 63326.03216826947 58124.16964472964 53116.7771737695 46052.97478204735 52214.15196526747 61588.79493839852 56498.57250018522 55614.99413352147 46237.21302215447 1.1084271995649548 1.3695901640509112 1.2570863563268737 1.148788469329211 0.9960153688324846 1.1292668513616761 1.3320178901978448 1.2219285897079055 1.2028189092381856 1.0 15.496766820634337 -5.758300038507769 24.23119015675498 1.1571556995540502 1.2574901721618124 0.13319402870303654 0.11097553939519805 115.51548817046267 891582.7282563775 0.031900342908698906 0.05237321614850182 1.7446164434423784e-06 5.758300038507769 0.10033447260776218 FDGSENRPFSPS(ph)PLNNISSTVTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FDGSENRPFSPSPLNNISSTVTVK 24 1 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 FDGS(0.068)ENRPFS(0.058)PS(0.827)PLNNIS(0.013)S(0.016)T(0.016)VT(0.002)VK;FDGS(0.001)ENRPFS(0.208)PS(0.782)PLNNIS(0.006)S(0.002)TVTVK 66.906 0.00053652 9518700.0 13880.7 16109.7 16585.300000000003 21384.8 18740.3 20997.3 23159.8 22496.0 22447.9 16301.900000000001 True False 16230.42835367829 17708.96455070173 16980.75645210051 20186.67898645703 15068.272743369169 19896.164624365887 20965.936081568267 21905.50383648223 22776.15807024551 19257.3054242306 0.8428192831825928 0.9195972209289125 0.8817825795468971 1.0482608309809036 0.7824704656971084 1.0331749009563633 1.0887263622660195 1.1375165608018825 1.182728194235695 1.0 14.233118227950829 -6.9676520749520074 6.197943112815372 1.107047405599335 0.9036196813937686 0.6229616119603929 0.076540247497027 0.11640867143620942 13.240162528770014 0.0268171138119233 0.023276161011173656 1.0773279445406216e-07 6.9676520749520074 -0.20342772420556632 FDHILYTGS(ph)TGVGK ddPTM_PC-9_AZD4547_30min_R2 1 FDHILYTGSTGVGK 14 0 P30838;A8MYB8;I3L3I9;C9JMC5;E9PNN6;C9JKT2 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 1 FDHILYT(0.159)GS(0.726)T(0.115)GVGK 77.051 0.024962 0.0 15285.0 21540.0 21405.0 34534.0 27579.0 19858.0 14959.0 25473.0 24232.0 22356.0 True False 20145.312052249537 28502.383762342095 21121.155714221462 26572.719844981333 23750.131898192183 18616.276120788243 16290.322020577132 21536.733161307504 25512.854049391528 21573.323244636817 0.9338066195831796 1.3211865153611815 0.9790404322371722 1.2317397530112741 1.1009027968881209 0.8629303844235634 0.7551141674302289 0.9983039199424961 1.1826112166438747 1.0 14.39696081192456 -6.6549296269388485 6.863241727626423 0.9474530415689015 1.1263655350509578 0.2136460681775696 0.14587348118603516 0.31701917387421136 18.271939704071475 0.04853241835048116 0.04841839073326013 2.2134533484434287e-07 6.6549296269388485 0.1789124934820563 FDHILYTGSTGVGK ddPTM_PC-9_AZD4547_30min_R2 2 FDHILYTGSTGVGK 14 0 P30838;A8MYB8;I3L3I9;C9JMC5;E9PNN6;C9JKT2 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 0 ; 110.98 0.00037154 9876600.0 74063.0 70619.0 94080.0 162031.0 126255.0 104941.0 89311.0 120771.0 83980.0 103487.0 False True 97613.49339389987 93445.21072018746 92832.43772922004 124677.2563039954 108726.6725699357 98379.02268061404 97259.50598166772 102108.6169914917 88419.01135143207 99863.95162899121 0.977464758820559 0.9357251460201547 0.9295890680763941 1.2484710876171727 1.0887479495491101 0.9851304807775493 0.973920062196223 1.0224772335350771 0.8853946785514885 1.0 16.607676374969238 -6.969883542003744 21.170889753998086 0.9733502323571233 1.036383093742177 0.10627064844281342 0.091428621770487 104.6055645359988 73531.8902921501 0.03528493696099545 0.031116953532630474 1.0718066764316384e-07 6.969883542003744 0.0630328613850537 FDHILYTGSTGVGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FDHILYTGSTGVGK 14 0 P30838;A8MYB8;I3L3I9;C9JMC5;E9PNN6;C9JKT2 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 0 84.75299999999999 0.0060117 5460500.0 69235.0 67011.0 74288.0 88663.0 97800.0 84864.0 82787.0 74511.0 73270.0 78229.0 False True 80955.11804641824 73663.40921972928 76059.30765880905 83695.49955932442 78636.79206317432 80413.5824454662 74944.81603402419 72555.16520093035 74341.43513677835 92411.29843957657 0.8760305223862969 0.7971255729935917 0.8230520395570535 0.9056847049286836 0.8509434819227353 0.870170464037413 0.8109919165677247 0.7851330565209057 0.8044626186633093 1.0 16.495781629526867 FDHILYTGSTGVGK ddPTM_PC-9_Lapatinib_30min_R1 2 FDHILYTGSTGVGK 14 0 P30838;A8MYB8;I3L3I9;C9JMC5;E9PNN6;C9JKT2 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 0 ; 159.12 0.0003702 18080200.0 204538.0 194348.0 224056.0 198332.0 205771.0 215478.0 196806.0 178844.0 214177.0 176469.0 False True 201621.25061232416 193897.99914670517 205634.98056117172 212917.99689615643 193667.95434135155 206262.5082437516 206995.6517008461 187153.74514212154 190054.13087620417 206971.43151983843 0.9741501478333185 0.9368346042874997 0.9935428240078699 1.0287313342360875 0.9357231233277152 0.9965747771521845 1.0001170218557693 0.9042491698869206 0.9182626291976306 1.0 17.65907211921919 -7.7543776727432 24.999918781301698 0.9334419225469496 0.9803241603533082 0.20194952616225792 0.03550373265284506 215.57331905501758 763181.9341784111 0.016967002827815388 0.009530794829405028 1.760444456458708e-08 7.7543776727432 0.046882237806358584 FDIYDPFHPTDEAY(ph)SPPPAPEQK ddPTM_PC-9_AZD4547_30min_R2 2 FDIYDPFHPTDEAYSPPPAPEQK 23 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 FDIYDPFHPTDEAY(0.524)S(0.476)PPPAPEQK;FDIYDPFHPTDEAY(0.787)S(0.213)PPPAPEQK 138.82 6.142400000000001e-08 127498000.0 333668.0 328222.0 491278.0 690476.0 600143.0 550600.0 392582.0 592426.0 484043.0 503239.0 True False 439767.4832744531 434313.3427689626 484763.332724657 531297.4259478583 516823.50367224147 516170.8949595125 427521.0374678937 500880.17429516575 509628.52478663 485620.75578403135 0.9055780216075228 0.8943467460894803 0.9982343772395189 1.0940583153001404 1.0642533242588312 1.0629094593087525 0.88035989478593 1.0314225006435283 1.0494372794339037 1.0 18.88947055918272 -5.332281209073713 4.279603973260666 1.0256160702242823 0.8991808022757846 0.4482813636433777 0.05494638629466471 0.1994602538673969 7.023472092389995 0.015634926346486853 0.03565954124872268 4.652847204672208e-06 5.332281209073713 -0.1264352679484977 FDIYDPFHPTDEAYS(ph)PPPAPEQK ddPTM_PC-9_AZD4547_30min_R2 2 FDIYDPFHPTDEAYSPPPAPEQK 23 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 FDIYDPFHPTDEAY(0.104)S(0.896)PPPAPEQK;FDIYDPFHPTDEAY(0.443)S(0.557)PPPAPEQK 143.57 3.5288000000000005e-09 131016000.0 111531.0 108413.0 157670.0 220547.0 199484.0 188543.0 147911.0 190462.0 145420.0 174373.0 True False 146995.53801108565 143455.3821182355 155579.1927802522 169703.296567183 171789.08994448514 176753.3764045614 161074.79245842542 161030.47428135492 153106.60431918595 168268.25434501035 0.8735785521949494 0.8525397893776234 0.9245902822600095 1.0085283004079324 1.0209239444075755 1.050426160850005 0.957250035578097 0.9569866574546178 0.909895956995325 1.0 17.36040349650561 -5.516559200350942 3.491610907106794 0.987130211343449 0.86478504343003 0.6373843269985549 0.03733288402189139 0.15719568358032343 4.0484974107728835 0.011460545602220209 0.023786648286265186 3.0439730260714953e-06 5.516559200350942 -0.12234516791341898 FDIYDPFHPTDEAYS(ph)PPPAPEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 9 FDIYDPFHPTDEAYSPPPAPEQK 23 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 FDIYDPFHPT(0.005)DEAY(0.441)S(0.554)PPPAPEQK;FDIYDPFHPT(0.002)DEAY(0.454)S(0.544)PPPAPEQK;FDIYDPFHPTDEAY(0.465)S(0.535)PPPAPEQK;FDIYDPFHPT(0.024)DEAY(0.45)S(0.526)PPPAPEQK;FDIYDPFHPTDEAY(0.149)S(0.85)PPPAPEQK;FDIYDPFHPT(0.001)DEAY(0.149)S(0.849)PPPAPEQK;FDIY(0.001)DPFHPT(0.011)DEAY(0.297)S(0.691)PPPAPEQK;FDIYDPFHPTDEAY(0.1)S(0.899)PPPAPEQK;FDIYDPFHPTDEAYS(1)PPPAPEQK 151.05 1.6369999999999997e-08 223925800.0 295096.4 312413.1 362223.0 430088.9 467997.0 406484.0 395681.0 395454.0 384421.5 321187.8 True False 345050.3921004256 343427.4079017508 370859.77005837654 405992.413300028 376296.3473945741 385167.26346581493 358199.2311976367 385073.75151814765 390042.9371834735 379416.605618774 0.9094235386395331 0.9051459604454318 0.9774473878220419 1.0700438707418003 0.9917761685229585 1.0151565792373858 0.944078951456184 1.0149101167834962 1.0280070281778244 1.0 18.533423295831426 -5.363330509132224 3.9381318143264736 1.0075073751138384 0.9069150591843946 0.6410607600565443 0.02993987081059096 0.14011104021833543 3.8273932183660526 0.00820313350415854 0.01872788662832108 4.3318109110165214e-06 5.363330509132224 -0.10059231592944373 FDIYDPFHPTDEAYS(ph)PPPAPEQK ddPTM_PC-9_Lapatinib_30min_R1 5 FDIYDPFHPTDEAYSPPPAPEQK 23 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 FDIYDPFHPTDEAY(0.143)S(0.857)PPPAPEQK;FDIYDPFHPTDEAY(0.328)S(0.672)PPPAPEQK;FDIYDPFHPT(0.005)DEAY(0.455)S(0.54)PPPAPEQK;FDIYDPFHPTDEAY(0.102)S(0.898)PPPAPEQK;FDIYDPFHPT(0.009)DEAY(0.332)S(0.659)PPPAPEQK 143.32 5.705600000000001e-09 213058000.0 544164.1 441934.8 588761.2 462720.2 579881.0 580514.9 459834.1 497717.1 602971.5 418075.9 True False 536404.2201465265 440911.5271229922 540355.5268199564 496750.18709733646 545773.5396699102 555687.6309733264 483642.05971246836 520842.8534716044 535058.5000986155 490339.7622638803 1.0939439576957175 0.8991959474942849 1.102002261299706 1.0130734346402166 1.1130517687370372 1.1332705885562644 0.9863406905438611 1.06220807194361 1.091199493241728 1.0 18.903422230747253 -5.309485949584853 24.999581086616285 1.0646922639924699 0.9965690391767469 0.1446841867294566 0.06410495124351581 606.5044655265629 315574.82334566204 0.0159615998897689 0.03322683562090465 4.9035888676154934e-06 5.309485949584853 -0.06812322481572297 FDLSHGS(ph)PQMVR ddPTM_PC-9_Lapatinib_30min_R1 1 FDLSHGSPQMVR 12 0 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;A8MY87 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 FDLS(0.015)HGS(0.985)PQMVR 71.316 0.015693000000000002 3472400.0 30480.0 31143.0 31388.0 28447.0 27048.0 28435.0 23956.0 26842.0 31508.0 19243.0 True False 30045.34961065258 31070.890296920206 28807.399801183845 30539.087276410126 25457.089818414024 27218.901335222483 25196.32446239176 28089.17731153864 27959.237246050914 22569.126910314248 1.331258835578688 1.3766988160592333 1.2764073646118168 1.3531355199413386 1.1279607722343905 1.2060236731082077 1.1164066985186238 1.2445841358046372 1.2388267103621695 1.0 14.462062988308551 -1.5228787455352466 0.06305412944643862 0.7304218054327611 2.3121806909190736 0.6491122836277553 0.06651532874986751 202.84307093146492 0.9559702002091837 4.649381007790097 29.124140384579523 0.029999999982391508 1.5228787455352466 1.5817588854863125 FDMVHIDT(ph)KS(ph)ASQMFELIHKK ddPTM_PC-9_Lapatinib_30min_R1 1 FDMVHIDTKSASQMFELIHKK 21 2 A0A0J9YYF7;Q86T65-4;Q86T65 A0A0J9YYF7 DAAM2 Disheveled-associated activator of morphogenesis 2 2 FDMVHIDT(0.999)KS(1)AS(0.002)QMFELIHKK 45.608000000000004 0.020344 6972100.0 12625.0 13858.0 9851.4 8987.7 11166.0 10605.0 13178.0 12082.0 11558.0 13099.0 True False 12444.965184858558 13825.912652432975 9041.455919503709 9648.68544008828 10509.237833200637 10151.448871462439 13860.29235955078 12643.373827509497 10256.21632886431 15363.144696679643 0.8100532430413302 0.8999402742995123 0.588515964538028 0.6280410443685791 0.6840551228728546 0.6607663386556802 0.9021780783296491 0.822967828340642 0.667585740507992 1.0 13.907185932454109 -7.255788714366405 24.76630670725164 0.8334302310354169 0.7097576530450824 0.25041396341945354 0.11434691774989626 695.154372522642 3046801.760925993 0.04673326437620282 0.03514758758763615 5.54895605761017e-08 7.255788714366405 -0.12367257799033449 FDPAMFNIS(ph)PGAVQF ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FDPAMFNISPGAVQF 15 0 Q8IVD9 Q8IVD9 NUDCD3 NudC domain-containing protein 3 1 FDPAMFNIS(1)PGAVQF;FDPAMFNIS(1)PGAVQF 110.44 0.00046368 5926100.0 22333.9 19584.7 24418.0 26997.0 24478.0 23357.0 24722.0 20414.9 17396.6 16822.0 True False 26114.588155367896 21528.9395852268 25000.21772578068 25484.44561545493 19681.71161679326 22132.117802351448 22380.153188219712 19879.030506374525 17650.992363866244 19871.695437121278 1.3141600442700323 1.0833972195955515 1.258081767853541 1.2824494868137304 0.9904394760412281 1.1137508559540215 1.1262326991189948 1.0003691214610477 0.8882479313211165 1.0 14.278427346972398 -6.999550345208048 0.6195223266521652 0.9508002882331218 1.233272680393565 0.5592270773766785 0.08950137172375577 0.6429090506240416 0.5216708397999696 0.07754434058696626 0.0687736087659942 1.0010359045998569e-07 6.999550345208048 0.2824723921604432 FDPCRPQLQPGSPS(ph)LVSEESPSAIDSDK ddPTM_PC-9_AZD4547_30min_R2 1 FDPCRPQLQPGSPSLVSEESPSAIDSDK 28 1 P31629 P31629 HIVEP2 Transcription factor HIVEP2 1 FDPCRPQLQPGS(0.384)PS(0.588)LVS(0.02)EES(0.006)PS(0.001)AIDSDK 59.661 0.010055 0.0 7865.6 9913.1 8758.7 7190.3 10075.0 10662.0 8781.9 13164.0 11020.0 9938.4 True False 10366.697185356501 13117.315713763865 8642.553915167091 5532.6874240276065 8676.260157158933 9995.303454519293 9563.472087205453 11129.806278626465 11602.494702224107 9590.459641013525 1.080938513209878 1.3677463025513152 0.9011615958642145 0.5768949175665274 0.9046761554633914 1.042213181501172 0.9971859999605587 1.1605081190300761 1.2097954776438586 1.0 13.227384245465437 -7.699398168335607 5.021684005983377 1.139001630842439 0.9754453910779375 0.10242530348146817 0.19075905913740948 0.48423423400603827 23.935835034705477 0.10685754417205642 0.058547838427887036 1.998029203562391e-08 7.699398168335607 -0.16355623976450162 FDPFGPIGT(ph)SPPGPRPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FDPFGPIGTSPPGPRPDR 18 1 Q5QPM7 Q5QPM7 PSMF1 1 FDPFGPIGT(0.5)S(0.5)PPGPRPDR 75.703 0.0041207 5604100.0 8794.9 12569.0 10995.0 14036.0 12594.0 13118.0 12802.0 14597.0 13670.0 11981.0 True False 10283.702862807002 13816.767254372833 11257.162498769705 13249.608425325981 10126.296106785452 12430.068987080802 11589.301881546347 14213.844216799936 13869.897888900801 14153.060458456175 0.7266062978387612 0.9762388350512264 0.7953871554363192 0.9361656063165901 0.7154845509569762 0.8782601490021955 0.8188548275876238 1.0042947430714495 0.9799928382708074 1.0 13.788826434784694 -7.763939146523944 24.98536188991559 0.9941078864017013 0.8400972451943386 0.46845618967017577 0.0777280867268786 56.65402463485839 566235.4649578417 0.03740625742688638 0.019281948924081093 1.7221098606431598e-08 7.763939146523944 -0.15401064120736274 FDPFGPIGTS(ph)PPGPRPDR ddPTM_PC-9_AZD4547_30min_R2 1 FDPFGPIGTSPPGPRPDR 18 1 Q5QPM7 Q5QPM7 PSMF1 1 FDPFGPIGT(0.216)S(0.784)PPGPRPDR 82.406 0.0012674000000000001 3833000.0 10607.0 8810.2 14261.0 15969.0 12686.0 12501.0 7799.2 16032.0 12159.0 11022.0 True False 13979.80536069421 11657.924857148862 14071.88982202814 12287.593768590572 10924.767876299566 11719.310493804705 8493.313690947607 13554.622778710072 12801.699916909527 10636.123134835703 1.3143703945009055 1.0960690008341976 1.3230281037213198 1.1552699806892917 1.0271381534234485 1.1018404305062357 0.7985347276706574 1.2743950598235954 1.2036058397049834 1.0 13.376684764094271 -6.010454523547422 6.630699380019577 1.0711096314277835 1.231614544631312 0.2641872635594572 0.13218103955938923 0.22464613716451065 48.82440981367495 0.039071406697777075 0.05420011294490526 9.762149998718656e-07 6.010454523547422 0.16050491320352855 FDPFGPIGTS(ph)PPGPRPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FDPFGPIGTSPPGPRPDR 18 1 Q5QPM7 Q5QPM7 PSMF1 1 FDPFGPIGT(0.29)S(0.71)PPGPRPDR 50.858000000000004 0.031152999999999997 5406100.0 8379.8 8119.1 11130.0 9839.4 11830.0 12805.0 13206.0 9442.8 9306.8 9243.9 True False 9798.334631405703 8925.110590737408 11395.381410760056 9288.130317765208 9511.996422365562 12133.483258085811 11955.032076839643 9194.936505473623 9442.894343264226 10919.745895327866 0.897304271118436 0.8173368388138148 1.0435573794474189 0.8505811771443544 0.8710822132258018 1.111150696581434 1.094808633042893 0.8420467466562366 0.8647540367495615 1.0 13.414651664395521 FDPFGPIGTS(ph)PPGPRPDR ddPTM_PC-9_Lapatinib_30min_R1 1 FDPFGPIGTSPPGPRPDR 18 1 Q5QPM7 Q5QPM7 PSMF1 1 FDPFGPIGT(0.24)S(0.76)PPGPRPDR 69.256 0.0052746 3543600.0 8178.8 7334.3 8707.3 7965.4 9423.8 9441.1 9169.0 7757.7 9834.3 8906.3 True False 8062.168812191768 7317.3178789680505 7991.419405149992 8551.20208779545 8869.510611903654 9037.326161279027 9643.725955738444 8118.151062876212 8726.657574229988 10445.74208810121 0.7718138878208969 0.7005072322533445 0.7650408499222906 0.8186304061188875 0.8491029681851854 0.8651684183906363 0.9232207606124657 0.7771732246887115 0.8354272487897784 1.0 13.350627367770029 -5.888753239478834 1.7068813258249713 0.8673189046032935 0.7337664615823225 0.5070681680813733 0.05725862639153314 0.3134815478972803 1.8598158850462159 0.018286823443836604 0.03389950703284178 1.2919531362108309e-06 5.888753239478834 -0.13355244302097102 FDQLFDDES(ph)DPFEVLK ddPTM_PC-9_AZD4547_30min_R2 1 FDQLFDDESDPFEVLK 16 0 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 FDQLFDDES(1)DPFEVLK 95.40100000000001 0.015271000000000002 0.0 578.4 1984.5 2346.6 2435.4 2239.0 812.73 1974.1 2331.6 2159.8 701.94 True False 762.3191685326226 2625.95081598737 2315.4825507587966 1873.956156554918 1928.1534979532357 761.9098646212218 2149.791075661564 1971.3047948378514 2273.96261868091 677.3652942539076 1.1254181089574253 3.8767129616225113 3.4183660875469175 2.7665370110510463 2.8465489955121255 1.124813850199451 3.173754389098836 2.9102536128739365 3.3570698675750643 1.0 9.403790260028032 -6.55715410749175 24.99812775951265 2.430725211483606 2.9043324247561286 0.04819965441487539 0.9892326125730637 652.9484763213145 476212.16817363194 0.32308170844007156 0.3230830481701743 2.7723361787598596e-07 6.55715410749175 0.47360721327252264 FDQLFDDES(ph)DPFEVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FDQLFDDESDPFEVLK 16 0 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 FDQLFDDES(1)DPFEVLK 170.09 2.9675999999999997e-21 0.0 858.2 1264.2 2375.5 1075.6 874.67 1031.2 1122.6 1278.6 2169.9 1169.3 True False 1003.4763097773673 1389.7014211932635 2432.1409291339187 1015.3376191422501 703.2846923711312 977.1220566761492 1016.2592010798259 1245.0381047886824 2201.630682452511 1381.2848338262936 0.7264803646599377 1.0060933032498844 1.7607816067860902 0.7350675213957616 0.5091525477934656 0.7074008435822943 0.7357347132124001 0.9013623217304179 1.5939005689027796 1.0 10.431795132119838 -9.284850939675474 14.995709443548746 0.9999971829716966 0.9524563014777344 0.0 0.3836912454264361 0.0 0.0 0.3908432798407917 0.09479341916743683 5.189781341571917e-10 9.284850939675474 -0.047540881493962184 FDQLFDDES(ph)DPFEVLK ddPTM_PC-9_Lapatinib_30min_R1 1 FDQLFDDESDPFEVLK 16 0 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 FDQLFDDES(1)DPFEVLK 98.337 0.0020645 742950.0 2190.9 2566.5 3066.1 2883.8 4908.1 2650.1 2726.7 3233.8 3282.2 2251.8 True False 2159.6573642381477 2560.55742693529 2814.017093488267 3095.8842720747884 4619.41520769587 2536.7614006848294 2867.8751841544336 3384.054153567309 2912.5240729017482 2641.0206296651036 0.8177358934572218 0.9695332926119488 1.0655036397217013 1.1722302496619892 1.7491022810683754 0.9605231296532906 1.0858965476987192 1.2813433244542383 1.10280246969183 1.0 11.366879855458762 -5.294352777813846 1.8746732514541142 1.2100938791010671 0.8447922088295732 0.2503638735275283 0.20901730097432616 0.5568441726862525 3.4987197364155174 0.06141144921015122 0.24352108719509402 5.0774683177483784e-06 5.294352777813846 -0.36530167027149396 FDQLLAEEK ddPTM_PC-9_Lapatinib_30min_R1 2 FDQLLAEEK 9 0 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580;Q7Z406;Q7Z406-6;Q7Z406-2;A0A0C4DFM8;A1L2Z2;P35749-4;P35749-3;P35749;P35749-2 P35579;Q7Z406;P35749-4 MYH9;MYH10;MYH14;MYH11 Myosin-9;Myosin-10;Myosin-14;Myosin-11 0 ; 112.13 0.010084000000000001 5765600.0 53234.0 55481.0 52812.0 45393.0 57197.0 52228.0 55946.0 50788.0 51244.0 46281.0 False True 52474.873398080046 55352.537153242505 48470.00122021536 48731.352646608946 53832.78491362859 49994.33018941447 58842.61013411962 53147.79589070949 45472.361096757464 54280.60918444385 0.9667333175973032 1.0197478986493367 0.8929524179715039 0.8977672391446695 0.9917498296805483 0.9210348030460613 1.0840447632813817 0.9791304240915002 0.8377275380650901 1.0 15.728149291581905 FDSDAAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 FDSDAASPR 9 0 A0A140T9Z4;A0A140T962;A0A140T921;S6AU73;Q5SS57;D9J307;A0A1W2PPR8;O19617;Q5QT33;Q53YP1;O78179;A0A140T937;F8W9Z8;A0A140T9U0;A0A140T9M0;A0A140T9J9;A0A140T9H5;A2AEA2;A0A140T912;A0A140T9U8;A0A140T9B3;A0A140T9W2;A0A140T930;A0A1W2PR11;A0A140T953;A0A140T9Z7;A0A140TA03;A0A140TA12;A0A140TA05;A0A140TA13;A0A140TA21;A0A140TA02;F6U0H7;A0A140T9D4;P01889;A0A1W2PNR7;A0A140T9T1;A0A140T9E1;A0A140T9L3;A0A140T942;A0A140T9M5;A0A1W2PRZ0;P10321;P10321-2 A0A140T9Z4 HLA-B;HLA-C HLA class I histocompatibility antigen, B-7 alpha chain;HLA class I histocompatibility antigen, Cw-7 alpha chain 1 FDS(0.003)DAAS(0.997)PR 79.97399999999999 0.019364 14089000.0 3813.0 3349.6 10383.0 15305.0 5829.3 3694.9 10839.0 4978.0 11295.0 12277.0 True False 5025.454684673045 4432.292695001908 10245.314635868317 11776.668709892841 5020.002316042336 3463.857318899208 11803.650002074703 4208.764483060051 11892.030640800474 11847.185966827974 0.4241897357519565 0.3741219819974374 0.8647888759875227 0.9940477631453933 0.4237295109655831 0.2923780658628961 0.9963252062662667 0.35525436123350795 1.0037852595627406 1.0 13.532256799532037 -8.28882448518836 23.01465357861536 1.0018934412255642 0.6039966142054402 0.2926449359850254 0.25509397450576604 427.0566343620377 358892.47506919317 0.24995061047829797 0.06464003124726758 5.142514380315146e-09 8.28882448518836 -0.3978968270201241 FDSDAAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 FDSDAASPR 9 0 A0A140T9Z4;A0A140T962;A0A140T921;S6AU73;Q5SS57;D9J307;A0A1W2PPR8;O19617;Q5QT33;Q53YP1;O78179;A0A140T937;F8W9Z8;A0A140T9U0;A0A140T9M0;A0A140T9J9;A0A140T9H5;A2AEA2;A0A140T912;A0A140T9U8;A0A140T9B3;A0A140T9W2;A0A140T930;A0A1W2PR11;A0A140T953;A0A140T9Z7;A0A140TA03;A0A140TA12;A0A140TA05;A0A140TA13;A0A140TA21;A0A140TA02;F6U0H7;A0A140T9D4;P01889;A0A1W2PNR7;A0A140T9T1;A0A140T9E1;A0A140T9L3;A0A140T942;A0A140T9M5;A0A1W2PRZ0;P10321;P10321-2 A0A140T9Z4 HLA-B;HLA-C HLA class I histocompatibility antigen, B-7 alpha chain;HLA class I histocompatibility antigen, Cw-7 alpha chain 1 FDS(0.001)DAAS(0.999)PR 81.33800000000001 0.017378 9524100.0 2338.0 2126.2 2647.8 2474.7 4037.4 3297.9 1809.7 2269.6 7513.7 2581.3 True False 2304.6596912633095 2121.276914533338 2430.108104803572 2656.6976933571946 3799.9280698338043 3156.8565047803854 1903.3974110698944 2375.0539015821523 6667.427983231329 3027.4742656339527 0.7612483175908067 0.7006754569684651 0.8026849748612835 0.8775294057869993 1.2551479340281362 1.0427360326775033 0.6287080397928083 0.7845001123683595 2.2023070712494297 1.0 11.563898981328158 -8.230572294654852 24.87179064025823 1.601153854144838 0.8622390190106414 0.46737132270021686 0.3178663926618861 456.8684908085609 368132.3305618929 0.2061268283765271 0.07788927832034981 5.880682134580356e-09 8.230572294654852 -0.7389148351341966 FDSPDLLLEAGDPAT(ph)SPCR ddPTM_PC-9_AZD4547_30min_R2 1 FDSPDLLLEAGDPATSPCR 19 0 A0A096LNM2;Q969U6-2;Q969U6 A0A096LNM2 FBXW5 F-box/WD repeat-containing protein 5 1 FDSPDLLLEAGDPAT(0.855)S(0.145)PCR 92.633 0.0021187 1765300.0 5421.9 5784.4 6323.2 6882.6 7829.5 6193.5 4925.8 7167.5 6310.3 5606.6 True False 7145.951417474116 7654.094179892837 6239.350236494519 5295.922905109996 6742.50907200753 5806.219465913076 5364.186657460986 6059.92756776475 6643.849575267224 5410.314640516222 1.3208014491357363 1.414722560232195 1.153232418271924 0.9788567314459714 1.2462323395232697 1.0731759336937712 0.9914740664600543 1.1200693435431226 1.2279968942126636 1.0 12.401496782062209 -5.361404602881454 4.698860576132194 1.0959284424858236 1.3665065369526745 0.5951588078382466 0.08958860935087974 0.14052782838670178 5.004706172861989 0.023499547153189453 0.05147043187044191 4.351063255825294e-06 5.361404602881454 0.270578094466851 FDSPDLLLEAGDPAT(ph)SPCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FDSPDLLLEAGDPATSPCR 19 0 A0A096LNM2;Q969U6-2;Q969U6 A0A096LNM2 FBXW5 F-box/WD repeat-containing protein 5 1 FDSPDLLLEAGDPAT(0.571)S(0.429)PCR 95.87299999999999 0.0021163 0.0 3373.0 3693.9 4331.6 3405.6 4496.0 3651.4 3986.0 2775.6 3907.5 2664.1 True False 3943.9822802133044 4060.605979865367 4434.881771684479 3214.7952731041696 3615.0410748060513 3459.914156077671 3608.4172238590622 2702.7434409912908 3964.6397952362754 3147.0802409960033 1.2532194854253522 1.2902772312472868 1.409205178156152 1.0215167796569227 1.1486968230787613 1.099404492776028 1.1465920623355483 0.8588098281650147 1.2597835109477624 1.0 11.619798248112911 -5.7671190391767215 24.999836081286904 1.0774130556147083 1.3148383017684246 0.5175684825349283 0.10668625489205778 103.51465794393907 455636.95643635455 0.02850220762777143 0.04361359157786546 1.7095466678271883e-06 5.7671190391767215 0.2374252461537163 FDSPDLLLEAGDPAT(ph)SPCR ddPTM_PC-9_Lapatinib_30min_R1 1 FDSPDLLLEAGDPATSPCR 19 0 A0A096LNM2;Q969U6-2;Q969U6 A0A096LNM2 FBXW5 F-box/WD repeat-containing protein 5 1 FDSPDLLLEAGDPAT(0.5)S(0.5)PCR 87.66799999999999 0.0044934 0.0 3209.0 3341.2 3184.3 3645.9 4097.6 5026.3 2625.9 3459.5 4579.2 2849.4 True False 3163.239071541471 3333.463656682716 2922.499145753464 3914.031648365862 3856.58722419156 4811.3368658775735 2761.8562533726213 3620.2409995256667 4063.442274886262 3341.914993413157 0.946534869311801 0.9974711096041946 0.8744983494534263 1.171194257208916 1.154005183193711 1.4396945689404474 0.8264292355778591 1.0832833889135673 1.2159023442832089 1.0 11.706459321430124 -5.767424137157829 24.999666249979278 1.1322891515824058 0.9452984010993177 0.2470544696705509 0.14988760218386418 204.9077617059628 855949.305488288 0.04271378721988158 0.06525480203156735 1.7083461090054446e-06 5.767424137157829 -0.1869907504830881 FDSPDLLLEAGDPATS(ph)PCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FDSPDLLLEAGDPATSPCR 19 0 A0A096LNM2;Q969U6-2;Q969U6 A0A096LNM2 FBXW5 F-box/WD repeat-containing protein 5 1 FDSPDLLLEAGDPAT(0.01)S(0.99)PCR 152.25 1.3599e-14 0.0 2121.9 3223.3 3603.3 4007.0 3640.5 2968.8 3635.4 3215.7 4291.3 2781.3 True False 2481.095760564664 3543.287921952419 3689.216337591349 3782.5007808692794 2927.170158547914 2813.110901726291 3291.0285939832506 3131.2912823157862 4354.052144158008 3285.5276732413154 0.755158990372148 1.0784532271057732 1.1228687457536395 1.1512612758296077 0.8909284747129017 0.8562128161748324 1.0016742883606602 0.9530558235190976 1.3252215708360011 1.0 11.681909378324775 -8.228551556595045 24.907962772463986 1.1626109824578001 0.9843413108852044 0.22679392324797587 0.1370183772599242 831.0198842138874 629384.1744927568 0.09372404673201407 0.03541953545463109 5.908108242219186e-09 8.228551556595045 -0.17826967157259577 FDSSLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FDSSLDR 7 0 Q02790;F5H1U3 Q02790 FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed;Peptidyl-prolyl cis-trans isomerase 0 83.61399999999999 0.045014 0.0 10646.0 16079.0 15160.0 11435.0 15096.0 10746.0 16976.0 9545.5 11733.0 8862.3 False True 12448.157531915458 17675.216857590964 15521.471894620163 10794.334022770201 12138.047167542742 10182.460842748163 15367.910384403285 9294.940739293263 11904.572928344778 10468.9648360718 1.189053333050099 1.6883442760920684 1.4826176358086023 1.0310794039136812 1.1594314583730343 0.9726330159848794 1.4679493746556211 0.8878567160018221 1.1371298991593186 1.0 13.35383117619279 -5.755300981120428 24.997867973214074 1.1023379144535639 1.4768391199375666 0.4391137151911415 0.18550115712809467 126.67465127809291 515860.09181053366 0.04843561131841751 0.08122775955166212 1.7567057340629133e-06 5.755300981120428 0.3745012054840027 FDSSLDRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FDSSLDRK 8 1 Q02790;F5H1U3 Q02790 FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed;Peptidyl-prolyl cis-trans isomerase 0 61.998999999999995 0.040289 5404100.0 19524.0 21932.0 24548.0 25539.0 28997.0 21569.0 24672.0 23792.0 25342.0 18071.0 False True 22829.02758342264 24109.264016461515 25133.317418808412 24108.132628555162 23315.246006706202 20437.88366994556 22334.889550188374 23167.485209707756 25712.57880764623 21347.129250042715 1.0694190921890334 1.1293913918853173 1.1773628727505887 1.1293383923511364 1.0921958514238888 0.9574066578486035 1.0462713411520512 1.0852740402863021 1.204498202379825 1.0 14.381754449620242 -6.521674510499881 24.97351888839538 1.0589721517153223 1.1278014943085046 0.19629899618067737 0.06457082972670078 79.35595781152979 1645723.449560403 0.022223604228639653 0.022516047218655796 3.008330102900155e-07 6.521674510499881 0.0688293425931823 FEDEGAGFEESS(ph)ETGDYEEK ddPTM_PC-9_Lapatinib_30min_R1 1 FEDEGAGFEESSETGDYEEK 20 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 FEDEGAGFEES(0.043)S(0.947)ET(0.01)GDYEEK 104.67 8.7675e-05 1215400.0 5758.4 9583.6 6620.4 7406.0 8315.8 6165.3 8648.8 9475.7 7107.5 7222.5 True False 5676.284160038773 9561.40976301463 6076.096267483034 7950.661945691758 7826.680993491842 5901.624491016251 9096.59254509659 9915.975614743562 6306.978504706964 8470.899501623688 0.6700922563124202 1.1287360641195088 0.7172905623916773 0.9385853231014946 0.9239492207399742 0.696693956749816 1.073863825601162 1.170592994621514 0.7445464916090733 1.0 13.048299458189971 -7.289851650690813 24.981936529536426 1.0114669125813396 0.8606637467838155 0.16564118187552712 0.16318442413459838 1318.5442348014574 1159345.3133206433 0.0649581886606365 0.043803601508982375 5.130366006498534e-08 7.289851650690813 -0.15080316579752406 FEDENFILK ddPTM_PC-9_AZD4547_30min_R2 4 FEDENFILK 9 0 P62937;F8WE65;C9J5S7;P62937-2 P62937 PPIA Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase 0 ;;; 168.25 0.0056744 69009000.0 147964.0 143340.0 171625.0 167412.0 162012.0 178553.0 167266.0 191975.0 153653.0 147290.0 False True 195013.47415760893 189671.85183352453 169349.14036221724 128817.74988961656 139519.43033068322 167388.0526838098 182152.34996282193 162309.67489663558 161774.78389118338 142133.42193158658 1.3720451636735744 1.334463416527182 1.1914800759791069 0.9063156866202849 0.9816088885683653 1.1776825633901862 1.2815588866248344 1.1419529107992663 1.1381896086977406 1.0 17.116886311110733 -5.356442427250235 3.5888545972824124 1.100082676932362 1.3569399779578182 0.5028400436496463 0.10302684308831862 0.2174186971608746 5.16615682856446 0.031070844564502084 0.07356789731708416 4.401062871674329e-06 5.356442427250235 0.25685730102545623 FEDENFILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 FEDENFILK 9 0 P62937;F8WE65;C9J5S7;P62937-2 P62937 PPIA Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase 0 ;;; 145.72 0.002199 41039500.0 121453.0 159292.0 140080.5 139467.0 164008.0 127656.0 152846.0 110320.2 120459.7 115233.1 False True 142012.59409390658 175105.45703584657 143420.5503782546 131653.11614811467 131871.809741279 120961.4946344556 138367.32037078813 107424.41164391399 122221.19522513727 136123.9488452821 1.0432594359668297 1.286367744406759 1.0536026290367595 0.9671561636648598 0.9687627405752379 0.8886128830419099 1.0164803588533553 0.7891661427337235 0.897866953331286 1.0 17.05456138287171 -5.659370223614517 2.4564209562542545 0.9227140025333803 1.1671197942151283 0.5584196797956295 0.08288587844093823 0.18989849909925344 2.3136337880164555 0.02337921865088421 0.04708087978342502 2.1909364284476943e-06 5.659370223614517 0.24440579168174803 FEDENFILK ddPTM_PC-9_Lapatinib_30min_R1 4 FEDENFILK 9 0 P62937;F8WE65;C9J5S7;P62937-2 P62937 PPIA Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase 0 ;;; 156.35 0.0004086 182751000.0 160559.0 140482.0 161696.0 140279.0 149365.0 121347.0 148629.0 166083.0 145599.0 145327.0 False True 158269.3992170858 140156.7225601885 148401.9790446102 150595.58561702594 140579.64436288847 116157.27168367307 156324.2823727179 173799.8224958006 129200.10739455909 170446.57831394428 0.9285572100225478 0.8222912067031048 0.8706656391263525 0.8835353992242957 0.8247724639209587 0.6814878469999196 0.917145324471022 1.0196732854072317 0.7580093931635657 1.0 17.37896011234792 -11.42829762404098 8.98739401770957 1.0201975932170675 0.8569995433226436 0.19065822004625044 0.08884724728008757 0.03557215926548824 0.0003743520654441186 0.08510607546306692 0.02123724043716729 3.729944553427953e-12 11.42829762404098 -0.16319804989442388 FEDYLNAESR ddPTM_PC-9_Lapatinib_30min_R1 2 FEDYLNAESR 10 0 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181;A0A0U1RRH9;A0A0U1RRE1;A0A5F9ZGZ7 G3V1Q4 SEPT7 Septin-7 0 ; 102.52 0.014666 11010300.0 37021.0 37288.0 48142.0 49199.0 42271.0 35724.0 31527.0 42484.0 47739.0 38057.0 False True 36493.07375118008 37201.66192696791 44183.95059349407 52817.25858305277 39784.70288798353 34196.16779671139 33159.313797204246 44457.9617354671 42362.131106043715 44635.10174223503 0.8175868840162019 0.8334620169974121 0.9898924583762275 1.1833121584010091 0.8913321877865933 0.7661272510185404 0.7428976859669156 0.9960313744148966 0.9490766112886315 1.0 15.445891093994286 FEEAKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FEEAKR 6 1 P31948-2;P31948;F5H783;F5GXD8 P31948-2 STIP1 Stress-induced-phosphoprotein 1 0 69.093 0.046274 3925400.0 17690.0 17995.0 21260.0 24043.0 38304.0 30730.0 26749.0 32816.0 40661.0 41571.0 False True 20684.567606573793 19781.42467518808 21766.91902899899 22695.94865845771 30798.606167564732 29118.464702926776 24215.141074010575 31954.61477142609 41255.59020194553 49107.493224145066 0.42121000785280666 0.40281886482981766 0.4432504613836953 0.46216874795186275 0.6271671418247377 0.5929535961043492 0.4931048091476298 0.650707512712433 0.8401078428833559 1.0 15.583655559130147 -8.344554059844894 0.3120356524749121 1.0739020047837278 0.3708235477993872 0.8849677905860878 0.0631254318031668 0.5768944453269772 0.182699201517289 0.14979666770876743 0.09992971919801745 4.523201551943774e-09 8.344554059844894 -0.7030784569843406 down FEEESKEPVADEEEEDS(ph)DDDVEPITEFR ddPTM_PC-9_AZD4547_30min_R2 5 FEEESKEPVADEEEEDSDDDVEPITEFR 28 1 E9PJF4;P54105 E9PJF4 CLNS1A Methylosome subunit pICln 1 FEEESKEPVADEEEEDS(1)DDDVEPITEFR;FEEESKEPVADEEEEDS(1)DDDVEPITEFR;FEEESKEPVADEEEEDS(0.998)DDDVEPIT(0.002)EFR;FEEESKEPVADEEEEDS(0.975)DDDVEPIT(0.025)EFR;FEEESKEPVADEEEEDS(1)DDDVEPITEFR 119.48 1.0418e-12 22219400.0 46916.2 36381.38 48400.100000000006 58481.8 53691.490000000005 57047.1 43775.44 52671.6 47951.74 55168.4 True False 61834.575682417395 48140.9496083379 47758.283049936465 44999.72454480306 46237.35339607913 53479.93581882456 47671.369355735886 44532.41449295821 50486.37108098257 53236.97110795407 1.1614968769922893 0.9042766447158977 0.8970886595537543 0.8452720657896277 0.868519610221981 1.0045638342267407 0.8954560780527456 0.8364941424382553 0.948332897801533 1.0 15.700140871688818 -4.7613944441101905 24.78414175802413 0.9046064297897916 1.161497098427981 0.6467814164787272 0.055322584629911645 0.578013545097128 314897.1800190406 0.013581722892072127 0.07577105552220385 1.7322300005479356e-05 4.7613944441101905 0.25689066863818955 FEEESKEPVADEEEEDS(ph)DDDVEPITEFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 FEEESKEPVADEEEEDSDDDVEPITEFR 28 1 E9PJF4;P54105 E9PJF4 CLNS1A Methylosome subunit pICln 1 FEEESKEPVADEEEEDS(0.995)DDDVEPIT(0.005)EFR;FEEESKEPVADEEEEDS(0.999)DDDVEPIT(0.001)EFR;FEEES(0.003)KEPVADEEEEDS(0.992)DDDVEPIT(0.005)EFR;FEEESKEPVADEEEEDS(1)DDDVEPITEFR;FEEESKEPVADEEEEDS(0.997)DDDVEPIT(0.003)EFR 105.03 1.5946e-10 13341060.0 23734.58 23298.809999999998 22277.960000000003 30453.920000000002 31361.99 30119.0 30093.399999999998 29979.09 26485.97 20835.1 True False 27752.375614676897 25611.76188032893 22809.15105603378 28747.685595340776 25216.833193428964 28539.50661853078 27242.735294651357 29192.170652971472 26873.277204717615 24612.33869943915 1.127579786447084 1.0406065913968814 0.926736436328724 1.1680192584053728 1.0245606279586745 1.159560940837415 1.1068730861920142 1.1860786985527987 1.0918619938108516 1.0 14.587094130794338 -5.786993805908018 24.99984395659 1.1119973645055081 1.0325373012758305 0.17606220698205555 0.07197300267612187 337.9978789578852 330661.34725277114 0.019713199599389237 0.029250947561615333 1.633075239339499e-06 5.786993805908018 -0.07946006322967758 FEEESKEPVADEEEEDS(ph)DDDVEPITEFR ddPTM_PC-9_Lapatinib_30min_R1 3 FEEESKEPVADEEEEDSDDDVEPITEFR 28 1 E9PJF4;P54105 E9PJF4 CLNS1A Methylosome subunit pICln 1 FEEESKEPVADEEEEDS(1)DDDVEPITEFR;FEEESKEPVADEEEEDS(0.999)DDDVEPIT(0.001)EFR;FEEESKEPVADEEEEDS(1)DDDVEPITEFR 126.93 2.6015e-11 19275000.0 57579.4 53073.1 58963.6 56134.25 59940.6 53873.4 53940.37 54261.6 61473.8 48811.1 True False 56758.30719723124 52950.21249775154 54115.84041407809 60262.55000336857 56415.01175575374 51569.36026702922 56733.13842634258 56782.792027709744 54549.973296187774 57248.03359829752 0.9914455332299685 0.9249263104702727 0.9452873227716841 1.0526571170325874 0.9854489003344814 0.9008057923680861 0.9910058889434019 0.9918732305488024 0.952870690353459 1.0 15.804938518755426 FEELCSDLFR ddPTM_PC-9_AZD4547_30min_R2 4 FEELCSDLFR 10 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;P17066;P48741 A0A0G2JIW1;P17066 HSPA1B;HSPA1A;HSPA6;HSPA7 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7 0 ;;; 153.24 0.0007751 29782700.0 58435.799999999996 64151.5 85902.5 103258.0 84825.4 88936.3 76075.7 96689.3 75694.90000000001 89688.6 False True 77017.1688598525 84887.21782404317 84763.37672230357 79453.46342019696 73048.85740298452 83375.09910168487 82846.28992184099 81748.19038407766 79695.97787979885 86548.62941308516 0.8898716176342868 0.9808037215573652 0.9793728369485689 0.9180210473464124 0.8440209613757369 0.9633324024548853 0.9572224364920512 0.9445347770200307 0.9208231074280853 1.0 16.401223352756595 FEELCSDLFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FEELCSDLFR 10 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;P17066;P48741 A0A0G2JIW1;P17066 HSPA1B;HSPA1A;HSPA6;HSPA7 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7 0 182.39 0.0071743 5148700.0 9457.3 11817.0 9218.3 10508.0 11800.0 8586.2 12095.0 8922.2 5825.4 7047.1 False True 11058.234099810645 12990.113664167688 9438.09923259743 9919.270827395654 9487.874707008761 8135.924556858758 10949.27403978309 8688.00170385233 5910.585454425949 8324.683445187091 1.3283669190092693 1.5604333485710993 1.1337487238693813 1.191549311479282 1.1397279871938155 0.97732539746752 1.3152781258143098 1.0436434923991362 0.7100072325084205 1.0 13.02317969789803 -4.905530354296371 0.31945354388054986 0.9274495952026975 1.8213067947452757 0.5047692961268833 0.15512442095690127 5.750170358220919 0.5065758849391859 0.16997167913010466 1.9976957039573582 1.242995755670673e-05 4.905530354296371 0.8938571995425781 FEELCSDLFR ddPTM_PC-9_Lapatinib_30min_R1 4 FEELCSDLFR 10 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;P17066;P48741 A0A0G2JIW1;P17066 HSPA1B;HSPA1A;HSPA6;HSPA7 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7 0 ;;; 182.39 0.0071743 25457700.0 69665.3 80532.6 93450.3 63316.9 80567.7 84066.7 77893.5 83129.8 75579.5 68354.8 False True 68671.86004694874 80346.13171260805 85767.17706259002 67973.4360449866 75828.86628819266 80471.36321004914 81926.44429417737 86992.3139882553 67066.94082258166 80169.83610295427 0.8565797734544474 1.002199026694122 1.069818540634755 0.8478679681681646 0.9458528291215796 1.003761104197689 1.0219110862215965 1.0851003097541523 0.8365607824924844 1.0 16.29077190437993 -6.758853659707872 24.9999962234651 0.9968132063656469 0.9492688801771485 0.06232126723327913 0.08389439280074305 210.40732203104398 2034327.7705928436 0.02838550334135626 0.02714583599490121 1.7423938932300454e-07 6.758853659707872 -0.047544326188498354 FEELNADLFR ddPTM_PC-9_AZD4547_30min_R2 4 FEELNADLFR 10 0 P11142;E9PKE3;P11142-2;E9PN89;E9PNE6;A8K7Q2;P54652 P11142 HSPA8;HSPA2 Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2 0 ;;; 242.12 1.1819e-18 51150900.0 179096.0 168515.0 214932.0 293699.0 220293.0 238681.0 188595.0 245860.0 181310.0 209672.0 False True 236044.80257178194 222984.1782595674 212081.86124592618 225991.23315431693 189709.11948397127 223756.2393385973 205379.58964307452 207867.98630075212 190893.67644829908 202331.44709919006 1.1666243975216783 1.1020737579673052 1.0481903049996777 1.1169357823231898 0.9376155916631641 1.1058895814099725 1.015065095355099 1.0273637107871219 0.9434701287670633 1.0 17.626361040740292 -1.5228787452839112 0.29918783170328456 0.9911261162712715 2.437576288003905 0.5113095912359835 0.050408642130269174 44.76572773084972 0.6377770023311098 0.049702448347653715 34.62263774067251 0.02999999999975314 1.5228787452839112 1.4464501717326337 FEELNADLFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 FEELNADLFR 10 0 P11142;E9PKE3;P11142-2;E9PN89;E9PNE6;A8K7Q2;P54652 P11142 HSPA8;HSPA2 Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2 0 ;;; 163.38 0.0028874 30016600.0 59387.1 73215.9 73903.0 68318.3 74724.0 53940.6 66710.1 59848.0 54229.0 44875.1 False True 69440.16308130902 80484.29068497376 75665.12779868826 64490.6471419171 60082.36861072227 51111.85997900067 60390.83638870058 58277.05341419762 55021.996533811354 53010.60039890386 1.309929760439855 1.518267857359299 1.4273584382993114 1.2165613416302794 1.1334029073167153 0.9641818729534244 1.139221890230644 1.0993471678431066 1.0379432815280676 1.0 15.693993260239665 -5.996741549433517 2.0886332897979973 1.062894162430624 1.4330092935357208 0.8400350479776985 0.06963291600959719 0.11596531493902265 1.016008307014193 0.021913826919706246 0.03459552767549593 1.0075310766776818e-06 5.996741549433517 0.37011513110509675 FEELNADLFR ddPTM_PC-9_Lapatinib_30min_R1 3 FEELNADLFR 10 0 P11142;E9PKE3;P11142-2;E9PN89;E9PNE6;A8K7Q2;P54652 P11142 HSPA8;HSPA2 Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2 0 ;; 208.63 0.00017829 63141000.0 159369.0 174008.0 174241.0 153661.0 179177.0 174118.0 189704.0 163427.0 179158.0 163561.0 False True 157096.36883530483 173605.09516701967 159915.5775697104 164961.7425380696 168638.16113553586 166671.37902888245 199525.94489119895 171020.4150395958 158979.33942262255 191832.30091866665 0.818925530700436 0.90498364631838 0.8336217456804194 0.8599268306123813 0.8790915832627965 0.8688389714907712 1.040106092330062 0.8915100023332635 0.8287412425398935 1.0 17.549486137710723 -7.03880705614251 24.979890301712928 0.9343948030094349 0.8618054851932828 0.3101970002328064 0.05768917171294015 752.4406113442726 484339.89204179187 0.022002882906859235 0.01704669785581609 9.145194444652872e-08 7.03880705614251 -0.07258931781615208 FEEPAPLSYDSRPR ddPTM_PC-9_Lapatinib_30min_R1 1 FEEPAPLSYDSRPR 14 1 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 0 111.31 0.0005332999999999999 4106000.0 11438.0 9401.3 13433.0 14138.0 13801.0 11992.0 8533.3 12107.0 13010.0 10180.0 False True 11274.892022527687 9379.531867464153 12328.590592879522 15177.755682985427 12989.252313809968 11479.130114717358 8975.112520242434 12669.535418776484 11544.676798626459 11939.599436002643 0.944327494650231 0.7855817875414758 1.0325799168524796 1.271211464366087 1.087913575613115 0.9614334363767023 0.7517096840936638 1.0611357178845375 0.9669232925699889 1.0 13.54346681570105 -10.080466533755079 15.826438794670805 0.9999822891230331 0.9864710199468515 0.0009249067352042895 0.1404717053583657 0.0 0.0 0.14837900808435736 0.03598719546801073 8.308707422011488e-11 10.080466533755079 -0.013511269176181617 FEETTADGRK ddPTM_PC-9_Lapatinib_30min_R1 1 FEETTADGRK 10 1 I6L8B7;Q01469 I6L8B7 FABP5 Fatty acid-binding protein, epidermal 0 91.65799999999999 0.0050183 4228300.0 22498.0 24422.0 27710.0 18244.0 30821.0 24627.0 21639.0 23904.0 25807.0 22021.0 False True 22177.174394372098 24365.45235948322 25431.790763693265 19585.724620199908 29008.169376417427 23573.76061834093 22759.361539559828 25014.667105842334 22900.34390024234 25827.300508861914 0.8586717913768271 0.9433991117702332 0.9846863691761769 0.758334174858097 1.1231591689756384 0.912745821432335 0.8812133320611881 0.9685358753331287 0.8866719885179146 1.0 14.65660923918805 -4.7588327593482935 24.267958334998713 0.9376535125324338 0.8586716444127495 0.0685143422101433 0.0894755183809679 149.31149168774618 1389688.7922170125 0.02110136094158113 0.13981963366403766 1.7424777477036803e-05 4.7588327593482935 -0.07898186811968433 FEFGEKLKR ddPTM_PC-9_Lapatinib_30min_R1 1 FEFGEKLKR 9 2 A0A286YFB1;C9JCA5;H9KVA2;C9JZN9;F8WA37;P45378-5;P45378-7;P45378-4;P45378-6;P45378-2;P45378-3;P45378 A0A286YFB1 TNNT3 Troponin T, fast skeletal muscle 0 44.349 0.037537 10783000.0 57649.0 42161.0 55242.0 43551.0 44866.0 45386.0 38534.0 44479.0 54323.0 47776.0 False True 56826.914688468176 42063.37879486411 50700.21600028665 46753.885821877084 42227.07008994986 43444.94657993348 40529.101971689925 46545.65671857263 48204.57169345003 56034.01794248159 1.0141502746920716 0.7506757562529567 0.9048113603477439 0.8343839606481464 0.753597040520913 0.7753316320191304 0.7232945888922812 0.8306678412094476 0.860273338651738 1.0 15.774015324872535 -4.749422696595361 24.91044282940266 0.8162872831212384 1.014150744074582 0.3316141416213234 0.07913020804111237 590.1190360211931 1223231.084766631 0.018980450770170538 0.3108793771973851 1.7806448312731727e-05 4.749422696595361 0.19786346095334362 FEGGDRDLEHLSK ddPTM_PC-9_AZD4547_30min_R2 1 FEGGDRDLEHLSK 13 1 A0A499FI48;P13667 A0A499FI48 PDIA4 Protein disulfide-isomerase A4 0 71.806 0.011286 9943400.0 10550.0 10465.0 45989.0 99040.0 62775.0 49647.0 28063.0 57883.0 34411.0 58587.0 False True 13904.68054636785 13847.606595771138 45379.15581132119 76207.85815274654 54059.77482537486 46542.56524165441 30560.552634765434 48938.5123690167 36229.89520855115 56535.88696249496 0.24594432480721498 0.244934807602071 0.8026610751048272 1.3479554712443385 0.956202824963855 0.8232393218227926 0.5405513962315447 0.8656185477638613 0.6408300489313187 1.0 15.786879309151981 -5.283198206166541 5.170287706570139 0.8766677998949882 0.23896607101960654 0.6022997654808047 0.2042441155559657 0.1207488356457996 9.925249530055478 0.05839872275468713 0.13556774298922641 5.209568991127136e-06 5.283198206166541 -0.6377017288753817 FEGLS(ph)PLQR ddPTM_PC-9_AZD4547_30min_R2 1 FEGLSPLQR 9 0 Q9Y3E2 Q9Y3E2 BOLA1 BolA-like protein 1 1 FEGLS(1)PLQR 68.355 0.04328 4334300.0 15678.0 19375.0 26635.0 29169.0 23519.0 21884.0 20509.0 24905.0 17538.0 24720.0 True False 20663.27787734173 25637.58985122464 26281.802497000146 22444.537706557625 20253.792817490914 20515.59002051212 22334.261268802493 21056.504509965966 18465.022875463383 23854.560324182396 0.8662191881354642 1.0747458558368275 1.101751704488854 0.9408908569907545 0.8490532855036013 0.8600280089721286 0.9362679909116284 0.8827035260264294 0.7740667874202902 1.0 14.541977475053502 -5.985229550493035 7.663459455457186 0.8805589330747929 1.0208604448190841 0.34911689424150194 0.0796853935579177 0.15850495595284428 50.960906416408775 0.02237764773920644 0.03253779640624596 1.0345951769794681e-06 5.985229550493035 0.14030151174429117 FEGLS(ph)PLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FEGLSPLQR 9 0 Q9Y3E2 Q9Y3E2 BOLA1 BolA-like protein 1 1 FEGLS(1)PLQR 73.95100000000001 0.028210000000000002 3299500.0 19159.0 28064.0 19188.0 22291.0 20738.0 22954.0 14459.0 16555.0 17043.0 15989.0 True False 22402.240292501254 30850.00845148531 19645.514690895234 21042.10753839706 16674.537768978615 21750.251831792422 13089.338845905217 16120.448791472418 17292.22163281172 18887.679131145647 1.18607692014209 1.6333403504623216 1.040123275839641 1.114065279926255 0.882826188077413 1.1515576731672879 0.6930093822020192 0.8534901868853708 0.9155291930122305 1.0 14.205157817554511 -5.642683286483426 1.46579482247443 0.909145508952642 1.4100388680023135 0.5324311512129423 0.165784440536985 0.3114856036387755 1.3102466453876451 0.05148713996366527 0.14060167750302546 2.276757173037614e-06 5.642683286483426 0.5008933590496715 FEGLS(ph)PLQR ddPTM_PC-9_Lapatinib_30min_R1 1 FEGLSPLQR 9 0 Q9Y3E2 Q9Y3E2 BOLA1 BolA-like protein 1 1 FEGLS(1)PLQR 70.41199999999999 0.037743 4055300.0 24160.0 20976.0 22498.0 26682.0 24971.0 24816.0 21373.0 18346.0 24216.0 18079.0 True False 23815.47396959864 20927.43136076161 20648.301284791443 28644.28328854274 23502.2548748749 23754.677528921435 22479.58936110782 19198.422135365778 21488.539074215096 21203.931061246756 1.1231631484184956 0.9869599792752349 0.9737959072376534 1.3508949451780807 1.1083914019051242 1.1202959234449001 1.0601614057401136 0.905418060448879 1.0134224173879014 1.0 14.372044134754045 -7.567406798075734 5.677202157658919 0.9701394378904187 1.108267070987235 0.2761233390272665 0.09952549833441078 0.27003900025691746 20.7917054946114 0.05023496237414716 0.028850114029730537 2.7076542186869796e-08 7.567406798075734 0.13812763309681642 FELLPTPPLS(ph)PSRR ddPTM_PC-9_AZD4547_30min_R2 1 FELLPTPPLSPSRR 14 1 H0YBT0;A0A087WUS5;P01106;P01106-2;H0YBG3;A0A0B4J1R1 H0YBT0 MYC Myc proto-oncogene protein 1 FELLPTPPLS(0.806)PS(0.194)RR 69.805 0.01323 2240500.0 24965.0 19581.0 24660.0 33168.0 25438.0 26290.0 29858.0 30212.0 25066.0 29945.0 True False 32903.35069574157 25910.175322675062 24332.99228744223 25521.630040491724 21906.37279184207 24646.082143998516 32515.304157389677 25543.42960269393 26390.937586746786 28896.63466454865 1.138656839376126 0.8966502716824158 0.8420701085062599 0.883204232491561 0.7580942572083501 0.8529049292454511 1.1252280597671303 0.8839586304501907 0.9132875815163372 1.0 14.818613864127515 -9.672681347446792 10.095863457864947 1.0000000252583572 0.9154193652980593 0.03836664070517637 0.11413957767840639 0.0 0.0 0.11350249020279957 0.027528397404516257 2.1248029103999123e-10 9.672681347446792 -0.08458065996029784 FELLPTPPLS(ph)PSRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FELLPTPPLSPSRR 14 1 H0YBT0;A0A087WUS5;P01106;P01106-2;H0YBG3;A0A0B4J1R1 H0YBT0 MYC Myc proto-oncogene protein 1 FELLPTPPLS(0.509)PS(0.491)RR;FELLPTPPLS(0.5)PS(0.5)RR 80.545 0.0074265 2037400.0 13190.8 13244.8 15068.0 18439.7 22192.0 20358.7 22630.0 28021.0 23054.0 19515.0 True False 15423.741909824388 14559.656212166215 15427.278265708213 17406.583391314005 17843.636906604952 19291.05393255695 20486.3225729881 27285.478440703635 23391.12113611698 23052.915019344997 0.6690582035669441 0.6315754948972132 0.669211605246552 0.7550708175823821 0.7740295269223589 0.8368162514965567 0.8886651668909062 1.1836020918745789 1.0146708612116158 1.0 14.492661569165112 -7.07198759809951 0.9733744961447022 1.0770116059054629 0.667195882221119 0.85290071912955 0.06530185369359282 0.19171406308477312 0.36953401620165427 0.044796668972269256 0.030213231032269607 8.472516082774e-08 7.07198759809951 -0.4098157236843438 FELLPTPPLS(ph)PSRR ddPTM_PC-9_Lapatinib_30min_R1 1 FELLPTPPLSPSRR 14 1 H0YBT0;A0A087WUS5;P01106;P01106-2;H0YBG3;A0A0B4J1R1 H0YBT0 MYC Myc proto-oncogene protein 1 FELLPTPPLS(0.846)PS(0.154)RR 79.837 0.0056408000000000005 2121100.0 11783.0 9355.9 8937.1 8439.0 9506.9 8276.4 8479.7 11152.0 11390.0 10780.0 True False 11614.972259262438 9334.236988374783 8202.326136203646 9059.632211678738 8947.722833284543 7922.437665230717 8918.737374509245 11670.162632377576 10107.138257982737 12643.308636552898 0.9186655639871473 0.7382748659151369 0.6487483911046839 0.7165554897146589 0.7077042165541939 0.6266111105068072 0.7054116632670347 0.9230307483468471 0.7994061165889857 1.0 13.62608643237786 -8.225885685132816 1.1520099950292 0.9732159482113835 0.7180418075584387 0.44618575114643266 0.08984332624791219 0.41677526125174663 1.091648805274652 0.08580021182813916 0.028386055795419324 5.944486086141333e-09 8.225885685132816 -0.25517414065294475 FEPES(ph)PGFESR ddPTM_PC-9_AZD4547_30min_R2 4 FEPESPGFESR 11 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 FEPES(0.999)PGFES(0.001)R;FEPES(1)PGFESR;FEPES(1)PGFESR;FEPES(1)PGFESR 204.32 7.3969e-06 170774000.0 174497.0 187388.0 268485.0 335553.0 277977.0 267073.0 209308.0 267152.0 210533.0 231602.0 True False 229983.4162369243 247957.50642793722 264924.7134750176 258196.44009217067 239384.69178228948 250372.88309030543 227936.00651667645 225869.79694223733 221661.34456836202 223493.68447416267 1.0290376516814366 1.1094609094271866 1.1853789698726123 1.1552739877176255 1.071102713016322 1.1202682692326824 1.019876722928282 1.0106316761194625 0.9918013794881417 1.0 17.769874538478334 -7.325189622090637 3.167275170810104 1.0019707897341774 1.1160040628436003 0.6237096983627841 0.04040882762335059 0.18473900375837413 3.668026425747117 0.019803868748329123 0.012944076107052414 4.7294471627973605e-08 7.325189622090637 0.1140332731094229 FEPES(ph)PGFESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FEPESPGFESR 11 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 FEPES(0.999)PGFES(0.001)R;FEPES(1)PGFESR;FEPES(0.999)PGFES(0.001)R 166.24 0.0003088 134846000.0 119071.0 102595.0 134129.0 147780.0 164859.0 134078.0 137553.0 120074.0 113527.0 103865.0 True False 139227.36854055073 112779.95357326628 137327.14404706535 139500.36570922445 132556.06240023376 127046.71364917074 124522.98404252033 116922.18472891935 115187.11760301706 122694.90230511226 1.1347445242209513 0.9191902145437963 1.119257128593381 1.136969532461268 1.08037139204528 1.0354685586955894 1.014899410676917 0.9529506322777977 0.9388093183902199 1.0 16.904715783976243 -7.366444601087933 1.8019805172054284 0.9598000742019115 1.0733019559819015 0.39298785918226964 0.060600735409463785 0.39298958792868105 2.4851952218614413 0.035233090257514185 0.020067996636875036 4.300860922184647e-08 7.366444601087933 0.11350188177998999 FEPES(ph)PGFESR ddPTM_PC-9_Lapatinib_30min_R1 4 FEPESPGFESR 11 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 FEPES(1)PGFESR;FEPES(1)PGFESR;FEPES(1)PGFESR;FEPES(1)PGFESR 184.96 0.00017287 157934000.0 373820.0 311336.0 372568.0 307247.0 335784.0 359687.0 314564.0 309756.0 344000.0 264132.0 True False 368489.2582498078 310615.12062042754 341936.897194069 329842.9693259456 316033.84529674443 344304.0254813492 330850.5847465267 324148.39457987377 305255.0975194083 309786.8642662331 1.1894928441288763 1.0026736329061474 1.1037811367631325 1.0647416252048574 1.020165416133147 1.1114222880201008 1.0679942338103507 1.0463593908271664 0.9853713398805374 1.0 18.24091644600219 -1.522878756544762 0.10664032007827252 0.9648913735231794 1.3958065193010551 0.33377453874782803 0.04872675796688519 155.70840079876166 1.1696367367812344 0.4927173476029745 9.847430343441657 0.029999999221881145 1.522878756544762 0.4309151457778757 FEPLDSACSS(ph)R ddPTM_PC-9_AZD4547_30min_R2 3 FEPLDSACSSR 11 0 Q9UPZ3;Q9UPZ3-2;G3V159 Q9UPZ3 HPS5 Hermansky-Pudlak syndrome 5 protein 1 FEPLDS(0.002)ACS(0.104)S(0.894)R;FEPLDSACS(0.006)S(0.994)R;FEPLDSACS(0.039)S(0.961)R 120.59 0.00085157 13700100.0 46804.0 50719.0 61204.0 92562.0 71872.0 63256.0 58704.0 83608.0 61001.0 63374.0 True False 61686.69841632239 67112.9248858974 60392.39497001678 71223.26096864429 61893.813401024905 59300.592320303185 63928.54227528314 70688.30472070808 64225.38832399027 61155.295549544324 1.0086894006807237 1.0974180450411946 0.9875251918468861 1.164629494937908 1.0120761063264305 0.9696722383143652 1.0453476138218005 1.1558819900304576 1.0502015851098085 1.0 15.900189809328799 -7.562130866973797 24.999872019433138 1.0819480350877473 1.041529017135743 0.026319979585752384 0.06441473627006003 452.8983754934836 288448.6997208286 0.029739618661986066 0.017170190293323798 2.7407481714156466e-08 7.562130866973797 -0.04041901795200431 FEPLDSACSS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FEPLDSACSSR 11 0 Q9UPZ3;Q9UPZ3-2;G3V159 Q9UPZ3 HPS5 Hermansky-Pudlak syndrome 5 protein 1 FEPLDS(0.001)ACS(0.286)S(0.713)R;FEPLDSACS(0.036)S(0.964)R;FEPLDS(0.002)ACS(0.258)S(0.74)R 110.64 0.0019117000000000001 13337900.0 75277.0 74681.0 83413.0 96306.0 99705.0 84073.0 81722.0 83615.0 68908.0 59813.0 True False 88019.90931147836 82094.83613046512 85401.88226556424 90910.28704826454 80168.52098833112 79664.0638779422 73980.70054395654 81420.19484741555 69915.6491388718 70656.62342055244 1.2457418009855723 1.1618845078660462 1.208688982450338 1.2866491865477505 1.1346214566632105 1.1274818979641432 1.047045513392552 1.1523363402578368 0.9895130244581557 1.0 16.108537186083133 -7.258537319133006 0.6261080395466557 1.00750750597121 1.22714660924881 0.7066278908693265 0.051068529832092396 0.4594707876677156 0.36555231138271754 0.046058677685842965 0.03311627532325251 5.5139481872484255e-08 7.258537319133006 0.21963910327759995 FEPLDSACSS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 4 FEPLDSACSSR 11 0 Q9UPZ3;Q9UPZ3-2;G3V159 Q9UPZ3 HPS5 Hermansky-Pudlak syndrome 5 protein 1 FEPLDS(0.008)ACS(0.192)S(0.801)R;FEPLDS(0.001)ACS(0.038)S(0.962)R;FEPLDSACS(0.185)S(0.815)R;FEPLDS(0.001)ACS(0.006)S(0.993)R 136.53 8.2391e-05 19431800.0 109689.0 145657.0 151044.0 132988.0 145819.0 137911.0 112526.0 118618.0 142094.0 110883.0 True False 108124.81474550071 145319.7401656395 138625.74536670107 142768.38115496282 137242.21311118425 132012.86801624295 118352.0456860533 124129.42531629896 126089.87740384538 130048.97880768971 0.8314160998172127 1.1174231547064393 1.065950279945637 1.097804707610061 1.0553117323138044 1.0151011505554177 0.9100574781218906 0.954482122461382 0.9695568435819949 1.0 16.988695545191256 -7.056701078313891 5.71448011809842 0.9550272990214729 1.0429916068026992 0.17322619670616557 0.07633027189389575 0.3319098189158236 23.36500039280371 0.028774157536117163 0.02252900886911863 8.7760466212097e-08 7.056701078313891 0.08796430778122633 FES(ph)PESQASAEQPEM ddPTM_PC-9_AZD4547_30min_R2 4 FESPESQASAEQPEM 15 0 O75436 O75436 VPS26A Vacuolar protein sorting-associated protein 26A 1 FES(0.992)PES(0.007)QAS(0.001)AEQPEM;FES(0.77)PES(0.23)QASAEQPEM;FES(0.998)PES(0.001)QASAEQPEM;FES(0.966)PES(0.034)QASAEQPEM 193.11 1.3857e-09 22668800.0 34965.9 34183.3 47524.3 58037.0 53379.0 44864.5 37544.2 48459.6 41794.399999999994 43559.5 True False 46084.32886409898 45232.38323413505 46894.096730174 44657.466312711564 45968.24723860905 42059.11572268625 40885.56106724727 40971.28231082704 44003.5666590413 42034.49516347993 1.0963454820824776 1.0760777085157784 1.1156098472883802 1.0624004437077312 1.0935839019793157 1.0005857227286914 0.9726668753421626 0.9747061824218928 1.046844180901978 1.0 15.359286125910561 -6.774037438597883 8.374856082307847 0.9955678117506433 1.0881760170462944 0.7917960722084088 0.02300233264313837 0.0667940073352676 30.108881591110748 0.00786634445170149 0.007188595640917291 1.6825290114672604e-07 6.774037438597883 0.09260820529565106 FES(ph)PESQASAEQPEM ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FESPESQASAEQPEM 15 0 O75436 O75436 VPS26A Vacuolar protein sorting-associated protein 26A 1 FES(0.958)PES(0.042)QASAEQPEM 236.42 1.3281999999999997e-108 0.0 7901.1 8165.9 8561.4 9682.9 10371.0 8362.8 8833.7 8116.1 9678.4 5596.4 True False 9238.600176161679 8976.55658544698 8765.53624529031 9140.398505385361 8338.876998846434 7924.2400461319885 7996.907985550381 7903.060974718773 9819.92829026609 6610.983018921978 1.3974623970019173 1.3578247833573691 1.325905121855791 1.3826080749600598 1.261367178675073 1.1986477689401411 1.2096397710690836 1.1954441498486086 1.4853960843885785 1.0 12.690649093623401 -6.37576671479803 4.1692893237845885 1.2295872616611225 1.362356958593361 0.28035724132849205 0.11129543732605268 0.3415801411112352 10.062059699009014 0.03415360997281556 0.03899360078210921 4.209526862004622e-07 6.37576671479803 0.1327696969322385 FES(ph)PESQASAEQPEM ddPTM_PC-9_Lapatinib_30min_R1 3 FESPESQASAEQPEM 15 0 O75436 O75436 VPS26A Vacuolar protein sorting-associated protein 26A 1 FES(0.896)PES(0.104)QASAEQPEM;FES(0.987)PES(0.013)QASAEQPEM;FES(0.978)PES(0.022)QASAEQPEM 213.67 1.1254e-38 8616200.0 54690.2 51554.0 56875.5 51196.4 52922.5 54034.7 47662.6 54250.2 59460.3 38374.3 True False 53910.30771904566 51434.6298804683 52199.41593577901 54961.55404218386 49809.70259963828 51723.761842037835 50130.33621310707 56770.86234209198 52763.25486928279 45007.246624459396 1.1978139469155586 1.1428077418207563 1.1598002510869216 1.221171214955299 1.1067040606871732 1.1492318620070465 1.1138281048693057 1.26137159235241 1.172327987746941 1.0 15.457869688268907 -10.800262768516887 3.1274673632542482 0.999077442739627 1.1685319159001901 0.5613507701846234 0.044930620738316135 29994475.533191357 41258223.292918056 263639.83920712513 0.011629625658606308 1.5839345478376094e-11 10.800262768516887 0.16945447316056317 FES(ph)PEVAER ddPTM_PC-9_AZD4547_30min_R2 1 FESPEVAER 9 0 A0A087X0X3;P52272-2;P52272 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 1 FES(1)PEVAER 86.344 0.011734999999999999 5913400.0 16512.0 15362.0 18227.0 24141.0 22810.0 21011.0 18924.0 22341.0 17674.0 17930.0 True False 21762.47252906408 20327.466079716785 17985.298070689758 18575.665424731982 19643.225229260068 19697.17884851855 20608.199339354356 18888.711795107407 18608.211557813876 17302.276157467255 1.2577809029866809 1.174843465375157 1.039475841617967 1.0735966329328968 1.1352971742265547 1.1384154702685005 1.1910686866745184 1.0916894183864638 1.0754776648148117 1.0 14.078674220017502 -14.522878745280336 0.0861559294935672 0.601629963298311 1.237597665021155 0.38755558217736474 0.05718061520781082 298.3760282655671 1.7929010876203368 22.341364906578086 1.7375005214946613 3.0000000000000132e-15 14.522878745280336 0.6359677017228441 FES(ph)PEVAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FESPEVAER 9 0 A0A087X0X3;P52272-2;P52272 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 1 FES(1)PEVAER;FES(1)PEVAER;FES(1)PEVAER 115.57 0.0019706 15447700.0 93319.0 99574.0 97701.0 116672.0 115143.0 88162.0 101324.0 97623.0 86390.0 78631.0 True False 109116.06356573521 109459.04865835921 100030.56237310577 110135.24609572769 92581.55571094144 83538.62951966896 91725.85719776602 95060.49969011864 87653.29031617683 92886.17785734631 1.174728749559645 1.1784212805748704 1.0769154752683627 1.185701130526356 0.9967204792636348 0.8993655616658787 0.987508145061558 1.0234084541201773 0.9436634420547899 1.0 16.503176308554785 -6.330678598224559 5.447307697833021 0.9713636176196567 1.150026566645805 0.8095367009312678 0.04254267663361025 0.094153641641796 5.323093419091908 0.013467400730801552 0.015404331542173905 4.6700486171442453e-07 6.330678598224559 0.1786629490261482 FES(ph)PEVAER ddPTM_PC-9_Lapatinib_30min_R1 4 FESPEVAER 9 0 A0A087X0X3;P52272-2;P52272 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 1 FES(1)PEVAER;FES(1)PEVAER;FES(1)PEVAER;FES(1)PEVAER 114.86 0.0020136 27774800.0 214188.0 196656.0 204192.0 200740.0 203443.0 191296.0 186724.0 182753.0 211193.0 164719.0 True False 211133.6398427311 196200.65511450826 187404.1219639141 215503.0892490092 191476.88272432727 183114.71601275634 196391.65507245122 191244.3715526275 187406.22037911724 193190.45967572884 1.0928781897259314 1.015581491155578 0.9700485328233748 1.1154955043366646 0.9911301160819338 0.9478455422701272 1.0165701525949864 0.9899265826771785 0.9700593947220765 1.0 17.559664325761858 -6.487719290759389 24.964769549018477 0.9843709465934444 1.0421416840964774 0.3567862897728955 0.04087626353370699 729.0465658473687 517655.8204969294 0.01260637352550765 0.01428774400040633 3.252974877290672e-07 6.487719290759389 0.057770737503033076 FESPATGILS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 FESPATGILSPR 12 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 FESPATGILS(1)PR;FESPATGILS(1)PR;FESPATGILS(1)PR 162.93 6.291e-05 70721000.0 37008.9 32573.1 49527.0 62874.0 54206.0 43654.0 49082.0 59028.0 41620.0 46842.0 True False 48776.960367059095 43101.717573312235 48870.239619633074 48379.37069361666 46680.43256366818 40924.30847904571 53450.202915566995 49906.578928499155 43819.94823108596 45202.07583759515 1.0790867335895815 0.9535340307859044 1.0811503390954242 1.0702909058300132 1.032705505193712 0.9053634754757973 1.1824723074136294 1.104077146983396 0.9694233598590697 1.0 15.464101407319056 -7.26689411747106 24.983372600131837 1.0726662845355333 1.0229124445391355 0.06965179848644498 0.07516811319979089 1210.5212004332689 5544309.060283711 0.03086104146746113 0.021468351008500173 5.408861768324309e-08 7.26689411747106 -0.04975383999639771 FESPATGILS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FESPATGILSPR 12 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 FESPATGILS(1)PR;FESPATGILS(1)PR;FES(0.003)PAT(0.001)GILS(0.996)PR 126.71 0.00025561 30072300.0 24306.9 28184.399999999998 27215.6 31733.4 42545.2 41951.6 40797.2 40697.5 35957.7 34131.2 True False 28421.578086841644 30982.360967789453 27864.523119737776 29955.480479070902 34208.77347327364 39751.58424442895 36932.593869850236 39629.23374756561 36483.513337214936 40318.916377569454 0.7049191952652122 0.768432382399687 0.6911029765482386 0.7429634318182217 0.8484546844692717 0.9859288844018604 0.916011569457677 0.9828943163168062 0.9048733600765059 1.0 15.29916924463443 -6.454472660653543 2.5497937950711713 0.9543629876960522 0.725334321730515 0.9067525602422155 0.03484469256354975 0.07672939205750014 0.9846745934293598 0.011282482260759712 0.01260946216450639 3.5117803088895817e-07 6.454472660653543 -0.22902866596553717 FESPATGILS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 FESPATGILSPR 12 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 FES(0.001)PAT(0.007)GILS(0.993)PR;FES(0.006)PAT(0.002)GILS(0.993)PR;FESPAT(0.001)GILS(0.999)PR;FESPAT(0.003)GILS(0.997)PR 96.756 0.0041842 54442700.0 34879.0 32041.9 38170.0 36420.6 37277.399999999994 41575.6 39600.3 36261.3 44107.5 28174.299999999996 True False 34381.61906397479 31967.708949198455 35031.8099404609 39099.09241955999 35084.8166221882 39797.50850545723 41650.609768243994 37946.13237638388 39139.64887743399 33044.190215105045 1.0404739483752996 0.9674229793830895 1.0601503535846153 1.1832365134397256 1.061754468600969 1.2043723343314108 1.2604518221543468 1.1483450533775852 1.1844638534837695 1.0 15.012109020884619 -5.596601033835851 3.963317629355173 1.1582470369136573 1.004851362727227 0.4038011100139882 0.07159857631133988 0.1922706727809276 5.903326055176154 0.019500974491627524 0.03624158860548311 2.5316226126047547e-06 5.596601033835851 -0.1533956741864302 FESPES(ph)QASAEQPEM ddPTM_PC-9_Lapatinib_30min_R1 1 FESPESQASAEQPEM 15 0 O75436 O75436 VPS26A Vacuolar protein sorting-associated protein 26A 1 FES(0.211)PES(0.789)QASAEQPEM 236.42 5.1455e-32 3475100.0 12044.0 11071.0 10508.0 10432.0 10845.0 8151.1 8218.4 9798.7 10577.0 7547.4 True False 11872.250351400899 11045.365779700207 9644.072802053008 11199.20408013184 10207.118422090361 7802.496454142149 8643.908539059961 10253.983373913039 9385.706879252275 8851.958033721648 1.341200478602972 1.2477878609029487 1.0894846953988924 1.2651668746585023 1.1530915965943593 0.8814430010194849 0.9764967825345399 1.1583859000291639 1.0602972634412977 1.0 13.111780896139333 -6.5342294218058 23.37472260064104 1.0221824610443377 1.2241531922945497 0.587173031816547 0.08744560843933659 82.01930098646113 168901.79590613756 0.030643598497551213 0.0306776558917716 2.922608063601207e-07 6.5342294218058 0.20197073125021192 FESPEVAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FESPEVAER 9 0 A0A087X0X3;P52272-2;P52272 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 103.56 0.012972999999999998 4150700.0 18156.0 20386.0 23570.0 20914.0 21943.0 21506.0 28419.0 21223.0 17555.0 18714.0 False True 21229.452202654255 22409.787353619588 24131.998189722766 19742.256384102842 17643.42666914349 20378.187500850727 25726.94658425758 20665.918737627242 17811.708664202884 22106.700060057505 0.960317557345962 1.0137102006513266 1.0916146744725859 0.8930440242310633 0.7981031371127941 0.9218104667584529 1.1637624120454393 0.934826033803504 0.8057153992144295 1.0 14.432196064934105 -5.774298475324488 24.99653746816688 0.9320952699910015 1.0210637665563762 0.14447345899104136 0.10127504350302695 483.1937593303357 939270.0303102244 0.030863226103194953 0.046109440612049114 1.6815180156634207e-06 5.774298475324488 0.08896849656537476 FESPEVAER ddPTM_PC-9_Lapatinib_30min_R1 2 FESPEVAER 9 0 A0A087X0X3;P52272-2;P52272 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 ; 117.89 0.0084355 21023000.0 91948.0 82878.0 77059.0 83436.0 79877.0 90452.0 79183.0 66623.0 86180.0 74712.0 False True 90636.8046588018 82686.10108300921 70723.50647634217 89572.1617743367 75178.79190422416 86583.57881391041 83282.70829460536 69718.54779921914 76473.50088436795 87625.86965251772 1.0343612567638303 0.9436265957861842 0.8071076128179698 1.022211387225451 0.8579520203605085 0.988105215471863 0.9504351697148883 0.795638868700414 0.8727274398259929 1.0 16.41906923692833 FEVNNTILHPEIVECR ddPTM_PC-9_Lapatinib_30min_R1 1 FEVNNTILHPEIVECR 16 0 A0A494C194;K7ES25;A0A494C165;P12955-3;P12955 A0A494C194 PEPD Xaa-Pro dipeptidase 0 107.63 0.0017807000000000003 0.0 6282.9 7231.6 7502.8 4976.3 5992.7 6914.0 6078.9 4324.0 5313.1 6509.8 False True 6193.304693857254 7214.855674508178 6885.948745645531 5342.273702450163 5640.221168101513 6618.304337321202 6393.635697713865 4524.908825538077 4714.682728576649 7635.010256236742 0.8111717582564064 0.9449700042792534 0.9018912240518169 0.6997074690353255 0.7387313151929609 0.8668363388136863 0.8374102303911318 0.5926526191424373 0.6175083687314512 1.0 12.89841437968185 -5.749879001446314 24.964886043303512 0.7539237308699334 0.8919069477178174 0.17907265905232328 0.11725786836312915 341.9699719983562 738484.7469762248 0.03243788843835173 0.05557495901841887 1.7787749245400463e-06 5.749879001446314 0.13798321684788406 FFDANYDGKDYDPVAAR ddPTM_PC-9_AZD4547_30min_R2 1 FFDANYDGKDYDPVAAR 17 1 Q15691 Q15691 MAPRE1 Microtubule-associated protein RP/EB family member 1 0 88.78 0.0034578000000000005 5525100.0 56188.0 49035.0 74583.0 103670.0 92479.0 76564.0 64820.0 70341.0 64581.0 76078.0 False True 74054.61521699693 64884.60481831223 73593.98068833347 79770.48318553357 79639.8871537369 71776.44097653507 70588.85442702111 59471.414725377144 67994.61981527554 73414.53237634114 1.0087187484539786 0.8838114569156093 1.0024443159437757 1.086576194160173 1.084797308869081 0.9776870961813281 0.9615106456738715 0.8100768717086133 0.9261738461632939 1.0 16.163778051774045 -7.419577464174917 3.233468383677297 0.8996099475312123 1.0087986746524678 0.2624596063446447 0.06929272736879886 0.32471281113762684 6.419873106898083 0.0347017933234102 0.021487989257505596 3.8055947197059005e-08 7.419577464174917 0.10918872712125549 FFDEESYSLLR ddPTM_PC-9_AZD4547_30min_R2 1 FFDEESYSLLR 11 0 A6NLM8;P51571 A6NLM8 SSR4 Translocon-associated protein subunit delta 0 250.06 4.5214e-27 2890800.0 5088.7 4325.6 7923.0 10580.0 8955.1 6655.3 8470.1 9164.7 5935.2 6743.1 False True 6706.800748464659 5723.765608281664 7817.935843203769 8140.944459370549 7711.838941277814 6239.1430389103625 9223.922491242092 7748.506198855056 6248.92255504905 6507.026121439906 1.0307013716091469 0.8796284971751552 1.2014606515017 1.2511006268358242 1.1851556759343855 0.9588317185869442 1.4175327283304309 1.1907907013504395 0.9603346349662814 1.0 12.667782629878934 -5.267381055330998 24.961849381062525 1.1606797058357348 0.9551649303138311 0.2234959192514927 0.13979574183395735 571.9162358554097 2402711.429474601 0.03607305742599381 0.0783877912518444 5.40280066527599e-06 5.267381055330998 -0.20551477552190367 FFIGGS(ph)LELEDLSYVRIPGSFKGLS(ph)SS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 FFIGGSLELEDLSYVRIPGSFKGLSSSK 28 2 Q9NXB0-2 Q9NXB0-2 3 FFIGGS(0.97)LELEDLS(0.023)Y(0.022)VRIPGS(0.141)FKGLS(0.593)S(0.6)S(0.653)K 49.638000000000005 0.024811 104100000.0 14785.0 28964.0 12434.0 24255.0 24885.0 19609.0 31799.0 31057.0 13572.0 27088.0 True False 14574.163188763065 28896.93563754286 11411.724516627999 26038.79361230806 23421.3132257924 18770.368780811594 33445.39662629804 32500.021599152646 12043.378440504088 31770.124707508818 0.4587379912084036 0.9095631793574017 0.3591967177242731 0.8195999811783501 0.7372118756668529 0.5908182279301928 1.0527310463592003 1.0229743162283313 0.3790787273069046 1.0 14.955383132633635 -7.2382170919442785 24.7786272841729 0.8656105892385009 0.656861615149315 0.17229613797139132 0.2331455183062696 1312.1130059337243 1400051.5403137535 0.08601894418553412 0.06658408928128155 5.778071452014396e-08 7.2382170919442785 -0.2087489740891859 FFMT(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 1 FFMTPPR 7 0 H0Y322;Q5TKA1;Q5TKA1-2;C9J5J4;H7C4T7;Q5TKA1-3 H0Y322 LIN9 Protein lin-9 homolog 1 FFMT(1)PPR 91.853 0.036623 3932300.0 17535.0 24473.0 36348.0 46554.0 49871.0 42907.0 29792.0 42027.0 33966.0 37306.0 True False 23110.765249342225 32383.418654401055 35866.0017706387 35821.69455213014 42947.272486121394 40224.018507133704 32443.430285248633 35532.69283438426 35761.37341703668 35999.928295062644 0.6419669800428975 0.8995411987762879 0.9962798113561157 0.9950490528350039 1.1929821674675827 1.1173360729346338 0.901208191842377 0.9870212113521775 0.993373462411627 1.0 15.13570641253605 -4.63617537977323 1.496949749514952 1.030017502976029 0.3794792521100898 0.7065003961376162 0.07501398519183065 0.97127468609411 1.5636545812972655 0.023547786459058397 1.0410362040958938 2.3111313048269334e-05 4.63617537977323 -0.6505382508659392 FFMT(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 1 FFMTPPR 7 0 H0Y322;Q5TKA1;Q5TKA1-2;C9J5J4;H7C4T7;Q5TKA1-3 H0Y322 LIN9 Protein lin-9 homolog 1 FFMT(1)PPR 95.90899999999999 0.031725 3904600.0 43077.0 28641.0 41300.0 38534.0 45280.0 40663.0 31612.0 31466.0 42352.0 28003.0 True False 42462.71408064568 28574.683524197797 37904.473422610296 41367.91890565569 42616.719423905146 38923.938280082715 33248.71468129606 32928.02523228058 37581.871773668565 32843.28123834794 1.2928889099870464 0.8700313259454079 1.154101295407503 1.2595549940775819 1.2975780073443364 1.1851415818537332 1.0123444865330549 1.0025802535781259 1.1442788405011077 1.0 15.003310647646167 -7.257761802340856 24.270989798432804 1.0400159128105955 1.170870639961943 0.2362834294572762 0.12018172319734399 367.3869846942562 2424660.14426906 0.049855468574100746 0.03709442799708931 5.523803204562728e-08 7.257761802340856 0.1308547271513476 FFPASADR ddPTM_PC-9_AZD4547_30min_R2 1 FFPASADR 8 0 P07237;H7BZ94;H0Y3Z3;I3L0S0 P07237 P4HB Protein disulfide-isomerase 0 95.62 0.029352999999999997 8532900.0 26233.0 21562.0 30780.0 51544.0 33253.0 37944.0 31236.0 24997.0 26453.0 29334.0 False True 34574.54831970312 28531.494832108656 30371.837088705284 39661.3271468616 28636.394938561367 35571.35568169948 34015.94348784995 21134.288023915662 27851.251575130173 28307.02558857469 1.2214122678314225 1.0079298067835347 1.0729434286081967 1.4011124914116637 1.011635604346916 1.256626400763803 1.201678480185481 0.7466092810699937 0.9838989083463268 1.0 14.788872542991058 -7.7453207060234925 24.985732604264676 0.898940551952199 1.1642409304929817 0.45524870741632284 0.12884330432106125 195.77240534433176 303469.86355007114 0.05952242353811057 0.03422807618539388 1.7975430240215945e-08 7.7453207060234925 0.2653003785407827 FFPASADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FFPASADR 8 0 P07237;H7BZ94;H0Y3Z3;I3L0S0 P07237 P4HB Protein disulfide-isomerase 0 99.375 0.024045 3478100.0 22193.0 17840.0 20620.0 20921.0 24437.0 19124.0 16922.0 19712.0 16003.0 16897.0 False True 25949.83656826976 19611.037299547395 21111.659001785476 19748.864196797153 19648.745272472286 18121.103774122086 15319.025655329418 19194.580886590422 16237.013600298433 19960.292343421585 1.3000729709663885 0.9825025085872906 1.0576828554689657 0.9894075626254987 0.984391657918178 0.9078576336630837 0.767475014481849 0.9616382644273483 0.8134657208890905 1.0 14.284845230450872 -1.5228787452803512 0.5038053002573274 0.8908288810265799 12.79912291386925 0.6576479411691052 0.08007901544973392 66.73309076874739 0.7016669608322403 0.043072045413126876 842.6352057382464 0.02999999999999906 1.5228787452803512 11.908294032842669 FFPASADR ddPTM_PC-9_Lapatinib_30min_R1 2 FFPASADR 8 0 P07237;H7BZ94;H0Y3Z3;I3L0S0 P07237 P4HB Protein disulfide-isomerase 0 ; 119.56 0.015915000000000002 16425500.0 63168.0 67378.0 46430.0 56730.0 55001.0 46493.0 49255.0 48312.0 46191.0 41737.0 False True 62267.21273640752 67221.9903806919 42612.70462498299 60902.11344573228 51765.94931612647 44504.602770476515 51805.18289343404 50556.751891627086 40988.48316720635 48951.18483894324 1.2720266719033668 1.3732454199395245 0.8705142636523547 1.2441397209507674 1.0575014575529524 0.9091629327646175 1.0583029412644633 1.0327993501682626 0.8373338316950779 1.0 15.57905615951285 -3.238059452461031 0.3969985065288661 0.9583215159087435 2.5256931739315878 0.4434560214037697 0.12688209488553365 17.00518330207203 0.8005088183010777 0.09329858198751106 16.335531575761696 0.000578016914739306 3.238059452461031 1.5673716580228443 FFTFDSPAELPSRT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 FFTFDSPAELPSRTPR 16 1 Q9NXH8 Q9NXH8 TOR4A Torsin-4A 1 FFTFDSPAELPS(0.025)RT(0.975)PR 104.55 0.0034592 0.0 22559.0 16485.0 27030.0 36374.0 36041.0 26457.0 19998.0 27546.0 23437.0 25094.0 True False 29732.292743650458 21813.45386825486 26671.564538911753 27988.536272697947 31037.329262944433 24802.63960759867 21777.78325874066 23289.398644108525 24675.831972416185 24215.466698019136 1.2278224126104746 0.900806667915231 1.1014268224321908 1.1558123831240243 1.281715097627391 1.0242478460936524 0.8993336172423271 0.9617571667951226 1.0190112080075957 1.0 14.563641187421036 -6.9907011136739206 24.908800883396676 0.9661174539434214 1.1233379639101004 0.38600219398488156 0.09771389323991517 220.8092437013973 591475.3959048277 0.03585656583398695 0.03158024744261762 1.0216423475254313e-07 6.9907011136739206 0.15722050996667902 FFTS(ph)STSLTLK ddPTM_PC-9_AZD4547_30min_R2 1 FFTSSTSLTLK 11 0 Q99567;J3KMX1;I3L245 Q99567 NUP88 Nuclear pore complex protein Nup88 1 FFTS(0.34)S(0.34)T(0.159)S(0.159)LT(0.001)LK 158.56 0.00099271 16436000.0 15155.0 12831.0 18580.0 22838.0 20621.0 21266.0 17733.0 22963.0 14891.0 13919.0 True False 19973.97475641753 16978.36982611939 18333.61706004366 17573.05194358267 17758.130094369666 19936.233658207406 19311.202646627073 19414.59598724547 15678.107859420981 13431.70004661388 1.4870771895664059 1.2640521875263007 1.364951346174943 1.3083267108851813 1.322105916059857 1.484267336898527 1.4377333159323649 1.4454310265914456 1.1672467226792649 1.0 13.713354297389788 -8.482644694486288 3.6115104826796367 1.0017198899392 1.383299896333829 0.7549310376864027 0.07256386082901073 0.10080349734779798 2.9680196148148847 0.07308799638867176 0.019277715681337803 3.2912078144393843e-09 8.482644694486288 0.3815800063946291 FFTSS(ph)TSLTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FFTSSTSLTLK 11 0 Q99567;J3KMX1;I3L245 Q99567 NUP88 Nuclear pore complex protein Nup88 1 FFTS(0.001)S(0.67)T(0.258)S(0.058)LT(0.013)LK;FFTS(0.012)S(0.522)T(0.233)S(0.233)LTLK 164.81 0.00019789 20842200.0 83991.0 79053.0 78568.0 96173.0 98099.0 85181.0 86717.0 90997.0 89219.0 67218.0 True False 98209.01740213319 86900.85939692368 80441.35909079913 90784.73860707291 78877.20515956382 80713.95840741956 78502.53798328807 88608.42516929108 90523.65908923504 79404.09130260472 1.2368256571045428 1.0944128693035373 1.0130631529330327 1.1433257042272187 0.9933644962822763 1.0164962167984897 0.9886460092354576 1.115917627362665 1.1400377185131965 1.0 16.276925723818344 -4.789706451893132 3.245390670429626 1.0530565069541413 1.2610242714580822 0.4819444114807908 0.05764198164882628 0.2894376077862045 4.753059242054575 0.015027833773425831 0.15204456264629257 1.6229066809802187e-05 4.789706451893132 0.20796776450394083 FFTSS(ph)TSLTLK ddPTM_PC-9_Lapatinib_30min_R1 1 FFTSSTSLTLK 11 0 Q99567;J3KMX1;I3L245 Q99567 NUP88 Nuclear pore complex protein Nup88 1 FFTS(0.014)S(0.58)T(0.177)S(0.22)LT(0.009)LK 142.1 0.00013762 7387600.0 20089.0 18401.0 18521.0 16915.0 21390.0 18574.0 20781.0 15546.0 22986.0 15051.0 True False 19802.527176128602 18358.39361505408 16998.274873127488 18158.98552678586 20131.882254358028 17779.63331810875 21856.938497786083 16268.323913463211 20397.07462668929 17652.545295803124 1.121794440648547 1.0399856398849616 0.9629361991875932 1.0286893602308524 1.1404520944152097 1.0071994162981042 1.2381748995133608 0.9215851675129813 1.1554749915604905 1.0 14.107588598223446 -4.752404532507699 23.308745447894115 1.055704076412848 1.1217947515067175 0.04591998040384815 0.0913555351116611 539.6896269827157 1392076.7227120586 0.021438223537143915 0.2404873183160683 1.7684609216702068e-05 4.752404532507699 0.06609067509386946 FFTT(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 2 FFTTPSK 7 0 O76021;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 FFT(0.04)T(0.957)PS(0.003)K;FFT(0.042)T(0.956)PS(0.001)K 131.62 0.010588 341300000.0 580780.0 612010.0 823350.0 1051040.0 887650.0 754370.0 770100.0 909330.0 840040.0 878840.0 True False 765455.9590255478 809830.2639921542 812431.8410326665 808738.9664061266 764415.1194543033 707199.1246469434 838637.408118621 768813.9428246269 884442.7994243512 848072.0790980791 0.902583610392653 0.9549073527493147 0.9579749894568916 0.9536205545950963 0.9013563095571492 0.8338903521019658 0.988875154350687 0.9065431603906323 1.0428863550901855 1.0 19.69382736155802 -8.260834025929688 24.999975484994046 1.0214431846818222 0.9263293043302098 0.45922732454448423 0.04185514516947842 49.551833365520736 2046651.2353971915 0.03326661012270346 0.010814717007871871 5.484865396545816e-09 8.260834025929688 -0.09511388035161239 FFTT(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FFTTPSK 7 0 O76021;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 FFT(0.039)T(0.958)PS(0.003)K;FFT(0.038)T(0.962)PSK;FFT(0.038)T(0.96)PS(0.003)K 146.79 0.0035091000000000002 353363000.0 703060.0 606370.0 707440.0 740230.0 932130.0 753460.0 807700.0 838540.0 674920.0 546283.0 True False 822074.1719320405 666566.4062402794 724308.0525811403 698757.3129580381 749485.8178511927 713947.2312094758 731188.8087583957 816529.2135065721 684789.4281768067 645319.783526151 1.2739020140372417 1.0329241769065762 1.1224017472754086 1.0828078276786963 1.1614176986111575 1.1063464183731224 1.133064299939853 1.2653094393680293 1.061162923651567 1.0 19.299654729203873 FFTT(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 2 FFTTPSK 7 0 O76021;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 FFT(0.002)T(0.997)PSK;FFT(0.038)T(0.958)PS(0.004)K 146.79 0.0035091000000000002 344560000.0 957840.0 853060.0 843460.0 790770.0 833680.0 686760.0 721480.0 620760.0 751840.0 589640.0 True False 944181.0259536572 851084.7919818516 774113.9746497567 848925.8637313913 784644.5814779433 657388.8757157522 758834.7041712477 649602.775795796 667159.8619738139 691558.4883540872 1.36529453669322 1.2306765173361371 1.1193760002746145 1.2275546870255893 1.1346033555967212 0.9505904226269295 1.0972820331903932 0.9393316497955999 0.9647193595463744 1.0 19.39949174647787 -4.914802557032475 0.36351705183771243 0.9531037362483258 1.5930427588048062 0.7783379985591944 0.06345633238038617 2.7010686059663422 0.3067773266311373 0.06072054382171317 0.7562001314950739 1.2167390400603432e-05 4.914802557032475 0.6399390225564804 FFVGGNWK ddPTM_PC-9_Lapatinib_30min_R1 1 FFVGGNWK 8 0 P60174;P60174-3 P60174 TPI1 Triosephosphate isomerase 0 97.068 0.027306999999999998 5618500.0 37750.0 38520.0 38348.0 35327.0 38653.0 38101.0 40422.0 33469.0 38158.0 34517.0 False True 37211.67807749784 38430.80930666176 35195.17546756077 37925.065427417314 36379.506534721884 36471.50904776901 42514.853373634985 35024.09192459155 33860.24421844646 40483.21745898854 0.919187762563464 0.9493022471742526 0.8693769338668595 0.9368095672197311 0.8986317990059977 0.9009044077268912 1.0501846454448585 0.8651508976546306 0.836402004182314 1.0 15.305036334296716 FFVS(ph)TPSQPSCK ddPTM_PC-9_AZD4547_30min_R2 2 FFVSTPSQPSCK 12 0 H0YLN8;Q96QT4 H0YLN8 TRPM7 Transient receptor potential cation channel subfamily M member 7 1 FFVS(0.913)T(0.086)PSQPSCK;FFVS(0.712)T(0.288)PS(0.001)QPSCK 134.4 5.7271e-05 10159200.0 52649.0 59891.0 83846.0 75433.0 74765.0 53589.0 72470.0 82820.0 64681.0 56135.0 True False 69390.28683276975 79249.5945176616 82734.1472559968 58043.08727823244 64385.170287839916 50238.07135849131 78919.68960700734 70022.07201426933 68099.90561112137 54169.730736164216 1.280978987522346 1.462986679842472 1.5273132454535667 1.07150407597434 1.1885820625808607 0.9274196248672122 1.4568964721532172 1.2926420542002426 1.2571579124659973 1.0 15.725199299109272 -5.75940061949732 24.99998326451456 1.18533944866771 1.427682349943252 0.3595429270390307 0.15393245634279729 63.340421331956534 776679.2287307449 0.04361033693062002 0.07097907728651116 1.7402008662357278e-06 5.75940061949732 0.24234290127554203 FFVS(ph)TPSQPSCK ddPTM_PC-9_Lapatinib_30min_R1 1 FFVSTPSQPSCK 12 0 H0YLN8;Q96QT4 H0YLN8 TRPM7 Transient receptor potential cation channel subfamily M member 7 1 FFVS(0.942)T(0.05)PS(0.005)QPS(0.002)CK 111.88 0.0010206 4589700.0 39192.0 41397.0 22746.0 16085.0 21111.0 20849.0 18072.0 14539.0 29991.0 7230.6 True False 38633.114893067446 41301.14778992412 20875.911682099122 17267.94455798703 19869.292485822927 19957.336871392774 19007.679733024874 15214.53501722899 26613.09776076912 8480.39957583112 4.555577192750522 4.870188889168753 2.461666044792846 2.0362182705635883 2.3429665439880694 2.353348647423475 2.241366053929367 1.7940823284541865 3.1381891292735355 1.0 13.04991652733841 -5.296505845144956 5.071033263602926 2.1953289024560196 4.729813430940688 0.7970001322089126 0.5138445226670643 0.0681201369268956 4.667381864864695 0.12446904901758588 0.2830089688669681 5.052358449536332e-06 5.296505845144956 2.534484528484668 FGDFLQHS(ph)PSILQSK ddPTM_PC-9_AZD4547_30min_R2 1 FGDFLQHSPSILQSK 15 0 Q96Q89-3;Q96Q89;Q96Q89-2;Q96Q89-5 Q96Q89-3 KIF20B Kinesin-like protein KIF20B 1 FGDFLQHS(0.985)PS(0.014)ILQSK 65.855 0.018734 10302000.0 35053.0 30967.0 60071.0 55092.0 58072.0 53552.0 40798.0 44277.0 34494.0 53607.0 True False 46199.124852306406 40976.47715730959 59274.41929030589 42391.39056291517 50009.70519568568 50203.38497434042 44428.94296380146 37435.00703424065 36317.282419103314 51730.23524670087 0.8930778031838312 0.7921185156397079 1.1458370333640837 0.819470283882359 0.9667403397102294 0.9704843740787391 0.8588583205144993 0.7236581634650132 0.7020513679457794 1.0 15.65872013185812 -7.521935668087344 5.588821780566516 0.7847611015950022 0.9303749791551987 0.17374187880920644 0.11794841142741752 0.23633609328650865 26.253257846365873 0.052412311043103274 0.03171811702990242 3.0065216248002996e-08 7.521935668087344 0.1456138775601965 FGDFLQHSPS(ph)ILQSK ddPTM_PC-9_AZD4547_30min_R2 1 FGDFLQHSPSILQSK 15 0 Q96Q89-3;Q96Q89;Q96Q89-2;Q96Q89-5 Q96Q89-3 KIF20B Kinesin-like protein KIF20B 1 FGDFLQHS(0.346)PS(0.648)ILQS(0.006)K 54.253 0.042526999999999995 11842000.0 36936.0 33115.0 56143.0 70177.0 66443.0 55265.0 50821.0 64363.0 50839.0 67225.0 True False 48680.879683473264 43818.77615088019 55398.50713681548 53998.7768738419 57218.53633966364 51809.27081354423 55343.97054667763 54417.1772646031 53526.24575012442 64871.47321169744 0.7504204432757551 0.6754706496010162 0.8539733166846931 0.8323963400310909 0.8820292419279627 0.7986448934876683 0.8531326299014612 0.8388460223035408 0.8251122273029051 1.0 15.985296581909362 -14.522858674967361 0.026700947674070045 2.1480940309636694 1.8462069472037047e-07 0.6241185825036869 0.0490511982203593 1312.9315245146358 2.6348935431273586 157.75956893066493 70.38766040273988 3.0001386440140072e-15 14.522858674967361 -2.1480938463429746 FGESEEVEMEVES(ph)DEEDDKQEK ddPTM_PC-9_AZD4547_30min_R2 3 FGESEEVEMEVESDEEDDKQEK 22 1 Q15459;Q15459-2;H7C1L2 Q15459 SF3A1 Splicing factor 3A subunit 1 1 FGESEEVEMEVES(1)DEEDDKQEK;FGES(0.001)EEVEMEVES(0.999)DEEDDKQEK;FGES(0.003)EEVEMEVES(0.997)DEEDDKQEK 66.264 0.0042239 32415100.0 75283.0 79822.0 53970.4 47148.9 59099.8 71447.5 85361.0 60517.0 73776.0 60098.5 True False 99221.42801632335 105622.90049571356 53254.71723236711 36279.44954824347 50894.81290680507 66979.87653036647 92957.96363383158 51165.48819231524 77675.64874331089 57994.46980755973 1.7108774051313005 1.8212581448920382 0.918272335432666 0.6255673975230367 0.8775804499237062 1.1549355783857078 1.6028763422148615 0.8822477102057356 1.3393630289415226 1.0 15.823627714934576 -5.257808628976714 24.94484467085669 1.0480619937032363 1.7660678516516644 0.5524492480762172 0.25776046518492624 232.82777591297793 1599610.6121459466 0.07175851262502024 0.17499772146660747 5.523207647428644e-06 5.257808628976714 0.7180058579484281 FGESEEVEMEVES(ph)DEEDDKQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FGESEEVEMEVESDEEDDKQEK 22 1 Q15459;Q15459-2;H7C1L2 Q15459 SF3A1 Splicing factor 3A subunit 1 1 FGES(0.054)EEVEMEVES(0.946)DEEDDKQEK;FGES(0.001)EEVEMEVES(0.999)DEEDDKQEK;FGES(0.001)EEVEMEVES(0.999)DEEDDKQEK 61.958999999999996 0.0086751 33018300.0 126038.0 137906.0 81627.0 123621.0 117595.0 83067.4 130455.0 93762.1 88670.5 91615.0 True False 147373.74403602895 151596.3962909965 83573.29725212125 116694.91615468968 94553.10391277092 78711.19931219977 118097.35798759022 91300.94422415689 89967.1383143947 108224.07427605915 1.3617464045948444 1.4007640841935294 0.7722246442038541 1.078271326738476 0.8736790270118997 0.7272984300278917 1.091230013077739 0.8436287843984273 0.8313043000479315 1.0 16.72366193455695 -5.253242095081909 24.936821333905268 0.9023934688146454 1.3812553185928655 0.732904290376438 0.11567808403628992 279.1374498698879 849154.4451597027 0.028639793208177295 0.07303607104700247 5.581589653380769e-06 5.253242095081909 0.4788618497782201 FGESEEVEMEVES(ph)DEEDDKQEK ddPTM_PC-9_Lapatinib_30min_R1 5 FGESEEVEMEVESDEEDDKQEK 22 1 Q15459;Q15459-2;H7C1L2 Q15459 SF3A1 Splicing factor 3A subunit 1 1 FGESEEVEMEVES(1)DEEDDKQEK;FGES(0.001)EEVEMEVES(0.999)DEEDDKQEK;FGES(0.008)EEVEMEVES(0.992)DEEDDKQEK;FGESEEVEMEVES(1)DEEDDKQEK;FGESEEVEMEVES(1)DEEDDKQEK 104.66 2.0377e-05 66608300.0 76587.0 103986.0 67513.9 88111.0 92180.0 81751.0 90390.0 86140.0 74347.0 86409.0 True False 75494.85533566443 103745.22680588067 61963.16775319056 94590.97686967948 86758.1536328529 78254.70030088892 95069.95191833327 90142.3788695306 65973.25795138218 101344.68051724495 0.7449316032213266 1.0236869490967238 0.611410164173805 0.9333590711116184 0.8560701281019877 0.7721638659423569 0.9380852693314874 0.8894633483421149 0.6509789918392025 1.0 16.628910839583035 FGEVVDCTLK ddPTM_PC-9_Lapatinib_30min_R1 3 FGEVVDCTLK 10 0 Q14103-3;Q14103;D6RAF8;D6RD83;H0YA96;H0Y8G5;Q14103-4;Q14103-2;D6RF44;D6RBQ9 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 0 ;; 157.99 0.0005225 33151500.0 144532.0 139770.0 144294.0 143192.0 144133.0 116880.0 142798.0 124443.0 133099.0 128881.0 False True 142470.94717607755 139446.371152443 132430.70431094748 153722.8173545093 135655.38031638067 111881.3148605875 150191.38172401965 130225.07608150647 118107.98902539453 151157.909126862 0.9425305496684677 0.9225211698013771 0.8761083364801151 1.0169684023976187 0.8974414974378181 0.7401618314704862 0.9936058429993816 0.8615167862120447 0.7813550062158525 1.0 17.205696942384094 -6.517917563083143 24.998646971937664 0.8679246944169571 0.9367140531969836 0.11647646488695951 0.0821263915191862 451.44117853199936 2274754.935312969 0.026007073925164388 0.026688230104514505 3.0344671260595505e-07 6.517917563083143 0.06878935878002657 FGEYNS(ph)NMSPEEK ddPTM_PC-9_AZD4547_30min_R2 1 FGEYNSNMSPEEK 13 0 E9PFK5;P78316-2;P78316 E9PFK5 NOP14 Nucleolar protein 14 1 FGEY(0.003)NS(0.649)NMS(0.349)PEEK 79.88600000000001 0.011777 47873000.0 72980.0 60478.0 70254.0 87815.0 67732.0 69276.0 73220.0 70084.0 65034.0 68884.0 True False 96186.1219216993 80026.33078825109 69322.38605685178 67570.60847822536 58328.58093942322 64944.16076864361 79736.43815406505 59254.12817010459 68471.56447045755 66472.39212665783 1.447008582727463 1.203903278157454 1.04287485133322 1.0165213905567738 0.8774858113768913 0.9770095326928766 1.1995421798892636 0.8914095953881213 1.030075227923052 1.0 16.020467652313243 -4.828714495328829 1.512136962349724 0.9967210684572976 1.596977785302821 0.7410386054014655 0.08276498658625464 0.5160686562904307 1.1899301840868308 0.024155926180563187 0.4556708300817018 1.4834930111783273e-05 4.828714495328829 0.6002567168455235 FGEYNSNMS(ph)PEEK ddPTM_PC-9_AZD4547_30min_R2 3 FGEYNSNMSPEEK 13 0 E9PFK5;P78316-2;P78316 E9PFK5 NOP14 Nucleolar protein 14 1 FGEY(0.001)NS(0.076)NMS(0.923)PEEK;FGEYNS(0.017)NMS(0.983)PEEK;FGEYNS(0.017)NMS(0.983)PEEK 129.38 9.3445e-05 40858500.0 133813.0 103829.0 114343.0 147659.0 140127.0 120174.0 127910.0 120505.0 106093.0 127214.0 True False 176362.75051669392 137389.69376324152 112826.73710961104 113618.49885880871 120672.7848180855 112659.5007825364 139293.7422054967 101883.72117941988 111700.85938684766 122760.27658092805 1.4366434764459752 1.1191706111273643 0.9190818092954649 0.925531466882182 0.982995380745445 0.9177195092768233 1.1346809088823548 0.8299404662244665 0.909910457176352 1.0 16.905484275773233 -4.823821670346729 2.365361217403939 0.9520491496982936 1.5263783818443317 0.7922121748274975 0.07574325300948134 0.21917248349125565 1.6253386123408304 0.019865715930308524 0.2539959526836322 1.5003007613385036e-05 4.823821670346729 0.5743292321460381 FGEYNSNMS(ph)PEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FGEYNSNMSPEEK 13 0 E9PFK5;P78316-2;P78316 E9PFK5 NOP14 Nucleolar protein 14 1 FGEYNS(0.413)NMS(0.587)PEEK;FGEYNS(0.003)NMS(0.997)PEEK;FGEYNS(0.084)NMS(0.916)PEEK 105.19 0.0011062000000000001 53822000.0 143309.0 139369.0 121466.0 157737.0 165249.0 144242.4 162268.0 177051.0 140683.0 109991.4 True False 167568.3832182299 153204.63326236696 124362.21010237 148899.50728025357 132869.6446998724 136678.074619767 146896.80032141577 172403.5988510412 142740.2227289123 129931.97012855676 1.2896624522235371 1.1791142173152909 0.9571332596536791 1.1459805245231796 1.0226093283154951 1.0519202817023057 1.1305670203882365 1.326875892672622 1.0985766058013502 1.0 16.987396928094775 -10.911059299662602 14.661061012916928 0.9999999540919805 1.1300446844811147 0.12142298831760834 0.10743220097254075 5.190426452655311e-10 0.0 0.10858799118264695 0.026336456312923095 1.2272716449552908e-11 10.911059299662602 0.13004473038913422 FGEYNSNMS(ph)PEEK ddPTM_PC-9_Lapatinib_30min_R1 5 FGEYNSNMSPEEK 13 0 E9PFK5;P78316-2;P78316 E9PFK5 NOP14 Nucleolar protein 14 1 FGEYNS(0.109)NMS(0.891)PEEK;FGEY(0.005)NS(0.06)NMS(0.935)PEEK;FGEYNS(0.019)NMS(0.981)PEEK;FGEYNS(0.007)NMS(0.993)PEEK;FGEYNS(0.046)NMS(0.954)PEEK 163.34 5.513e-05 98927000.0 351361.0 303838.0 275013.0 261493.0 297277.0 258014.0 254209.0 238222.0 248356.0 227938.0 True False 346350.52770828444 303134.48177875177 252402.4927208795 280724.0675350762 279791.75132906955 246979.34268001033 267370.69816581026 249290.66379216735 220383.53197537822 267336.7795917068 1.2955588386949686 1.133904890459582 0.9441368041702459 1.050076491397163 1.0465890692495987 0.9238509682701063 1.000126875823653 0.9324966963876029 0.8243666745442266 1.0 18.028298808405147 -1.5228787455739026 0.5865764436204477 0.945261728629472 21.190825832095854 0.7397228377036531 0.06289916740481465 82.8836088159138 0.6727863878557857 0.029971491647800302 2141.7387762088433 0.029999999979721248 1.5228787455739026 20.245564103466382 FGGEHVPNS(ph)PFQVTALAGDQPSVQPPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FGGEHVPNSPFQVTALAGDQPSVQPPLR 28 0 Q60FE5;P21333-2;P21333;A0A087WWY3;H0Y5F3 Q60FE5 FLNA Filamin-A 1 FGGEHVPNS(0.982)PFQVT(0.018)ALAGDQPSVQPPLR;FGGEHVPNS(0.998)PFQVT(0.002)ALAGDQPSVQPPLR 69.845 9.2447e-05 7140800.0 25045.8 25802.0 30489.0 32259.0 40568.0 33243.0 32312.0 40461.0 29016.0 24703.8 True False 29285.5592629014 28363.452040522545 31215.973390176394 30451.6328150891 32618.991619824694 31499.678559043106 29251.173441378323 39398.941621973136 29440.30410712111 29182.403384826808 1.0035348657447531 0.9719368095387897 1.0696848021231495 1.0434929712102539 1.1177623443031672 1.0794065911453048 1.0023565590415788 1.3500924205049658 1.008837542230274 1.0 14.832811084209851 -5.57406269783265 0.854325987117944 1.1098174190433339 0.970150686933058 0.11840520548014888 0.09780007428565816 1.7352598675551927 2.0323052903914585 0.040278023516557654 0.18450770877443717 2.6664736856735872e-06 5.57406269783265 -0.13966673211027592 FGGPVHHQAQR ddPTM_PC-9_AZD4547_30min_R2 1 FGGPVHHQAQR 11 0 Q15717;Q15717-2 Q15717 ELAVL1 ELAV-like protein 1 0 83.647 0.005300399999999999 3731500.0 28133.0 27490.0 38446.0 49681.0 42093.0 43771.0 33656.0 39842.0 34879.0 40214.0 False True 37078.708797248044 36375.604903750456 37936.18091982987 38227.81301379852 36249.11352806857 41033.992450549995 36651.318799688765 33685.33437807926 36722.63273311025 38806.12010018897 0.9554861115081558 0.9373677350334573 0.9775824231303437 0.9850975288202637 0.9341081621785747 1.057410334880404 0.944472642589958 0.8680418009095225 0.9463103406962714 1.0 15.243996576856489 -7.515109336626168 24.987439981104384 0.9255570859030267 0.9740498212096429 0.11137148656232976 0.04432773657785542 592.5495778154566 1905734.7110720237 0.019434232483300142 0.011859327597109977 3.054152112595167e-08 7.515109336626168 0.04849273530661624 FGGPVHHQAQR ddPTM_PC-9_Lapatinib_30min_R1 2 FGGPVHHQAQR 11 0 Q15717;Q15717-2 Q15717 ELAVL1 ELAV-like protein 1 0 ; 101.46 0.0015665999999999998 4621700.0 40194.0 42531.0 40984.0 40388.0 41505.0 43737.0 40914.0 38303.0 43137.0 37449.0 False True 39620.82618932312 42432.52208259685 37614.45372281505 43358.26825041838 39063.757501969594 41866.4704659267 43032.32672626052 40082.6972119762 38278.45680725209 43922.009752344115 0.9020722506262036 0.9660878981142759 0.8563919077224732 0.9871649429271473 0.889389117716426 0.9532002452071832 0.9797440273999277 0.9125879584742133 0.8715096832564492 1.0 15.422656449225064 -5.774313786080904 24.99999722302537 0.9381545358120185 0.9139743818625717 0.09125876709549563 0.04672196523663864 736.1828940986131 1429546.3211582555 0.012850157849295872 0.019190927153398336 1.681458735935016e-06 5.774313786080904 -0.024180153949446725 FGGS(ph)GSQVDSAR ddPTM_PC-9_AZD4547_30min_R2 2 FGGSGSQVDSAR 12 0 Q13200;Q13200-3;Q13200-2 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 1 FGGS(0.678)GS(0.322)QVDSAR;FGGS(0.676)GS(0.324)QVDSAR 148.85 8.1305e-05 24228000.0 35149.0 30706.0 45083.0 66202.0 60441.0 58952.0 44208.0 58080.0 39408.0 51624.0 True False 46325.650855382344 40631.11401144276 44485.169963291075 50940.15171070406 52049.81043760227 55265.72212069229 48142.426357756165 49105.07054562631 41491.02642697348 49816.6594731227 0.9299228680794255 0.8156129784929524 0.8929777795978453 1.022552540645314 1.0448273928460499 1.1093823372582718 0.9663921039051239 0.9857158441569067 0.8328745216117692 1.0 15.604340662405983 -5.6813180164860615 5.30583008093854 0.9995220158038721 0.8692783443539405 0.3542492056016614 0.07103031985260227 0.21863175711925514 10.516393093992837 0.02042764271452372 0.03571444987846897 2.0829650524818263e-06 5.6813180164860615 -0.13024367144993165 FGGS(ph)GSQVDSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FGGSGSQVDSAR 12 0 Q13200;Q13200-3;Q13200-2 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 1 FGGS(0.929)GS(0.064)QVDS(0.006)AR;FGGS(0.765)GS(0.234)QVDS(0.001)AR;FGGS(0.821)GS(0.148)QVDS(0.031)AR 115.68 0.00071154 22282900.0 52300.0 55036.0 67770.0 73185.0 88870.0 77051.0 71332.0 67574.0 77123.0 67973.0 True False 61153.357027914564 60499.61035974725 69385.89381915626 69084.68171897143 71456.56145863282 73010.30991946669 64574.91656104226 65800.25410057142 78250.77797261866 80295.96682602809 0.7615993610290721 0.7534576486366708 0.864126762051325 0.8603754889539172 0.8899147028574047 0.9092649706510572 0.8042112090256341 0.8194714716261706 0.974529370100984 1.0 16.29303990420091 -1.5228787769211385 0.05594886558165535 1.2215997926230961 0.14057288204407958 0.5938525199755427 0.050062690567493934 319.3706835334241 1.3459368181009366 5.608153170158142 28.73435675884993 0.029999997814330985 1.5228787769211385 -1.0810269105790167 FGGS(ph)GSQVDSAR ddPTM_PC-9_Lapatinib_30min_R1 3 FGGSGSQVDSAR 12 0 Q13200;Q13200-3;Q13200-2 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 1 FGGS(0.993)GS(0.007)QVDSAR;FGGS(0.844)GS(0.156)QVDSAR;FGGS(0.679)GS(0.321)QVDSAR 156.2 0.00019627 25501200.0 70715.0 72659.0 78567.0 68046.0 83476.0 80994.0 71308.0 71953.0 79774.0 63586.0 True False 69706.59113245712 72490.76254965566 72107.52453739036 73050.32983480161 78566.10580013038 77530.07542623566 74999.97932727629 75296.19905734083 70789.01206253858 74576.7553769809 0.9346959488931182 0.9720289141464967 0.9668900741644131 0.9795321540275747 1.0534932151845915 1.0396010799119098 1.005675011579091 1.0096470230800896 0.94921013531233 1.0 16.18643841045872 -6.027568003238597 8.559040068192344 1.011885629060744 0.9615109398587515 0.42084871084680864 0.02733398254759089 0.29880706579220623 86.4540876466018 0.00845610671462594 0.01123596849203926 9.384950725639347e-07 6.027568003238597 -0.05037468920199262 FGINIPS(ph)PEHSNTIDVCNTVDIK ddPTM_PC-9_AZD4547_30min_R2 1 FGINIPSPEHSNTIDVCNTVDIK 23 0 Q9HCI7;C9IZ03;Q9HCI7-2 Q9HCI7 MSL2 E3 ubiquitin-protein ligase MSL2 1 FGINIPS(0.997)PEHS(0.003)NTIDVCNTVDIK 97.18799999999999 4.635e-06 8276000.0 35595.0 38532.0 44986.0 56266.0 45945.0 52014.0 41850.0 57447.0 48900.0 49488.0 True False 46913.46957800608 50986.715465671616 44389.45624666976 43294.74300103434 39566.32981842847 48761.556357471985 45574.56892580742 48569.88615073338 51484.75416867141 47755.440182974904 0.9823691164453136 1.0676629776694777 0.92951622007025 0.9065928998905798 0.8285198433273808 1.0210680955016256 0.9543325064367226 1.0170545170275456 1.0780919194003373 1.0 15.54337747035103 -7.845274181934401 3.3432061624341696 1.041991454151993 0.9541768748895338 0.23586446400979355 0.06321275321634004 0.3757079173505608 8.204051785759008 0.04233284607000836 0.01862143952806467 1.4279921435394126e-08 7.845274181934401 -0.08781457926245917 FGLGT(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 1 FGLGTPEK 8 0 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 FGLGT(1)PEK 88.134 0.027393999999999998 9712900.0 56916.0 58116.0 44423.0 57833.0 72618.0 65737.0 55835.0 71827.0 70434.0 72095.0 True False 75014.10407365607 76900.86047967848 43833.921994527445 44500.495360943 62536.244177922264 61626.45499809937 60804.20683327254 60727.787570259985 74156.99744613918 69570.97599401014 1.0782384895694803 1.1053583679248573 0.6300604723196843 0.6396416713310787 0.8988841005091902 0.8858069635735056 0.8739881245665952 0.8728896885892254 1.0659186016381874 1.0 16.08619793960829 -8.251483881303745 21.104482143551724 1.0329592627936754 0.8662780482901854 0.15981686844159393 0.14593483183699912 145.59051887980152 308650.7259250321 0.11199817504575132 0.04079261355671728 5.6042321690079426e-09 8.251483881303745 -0.16668121450349005 FGLGT(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FGLGTPEK 8 0 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 FGLGT(1)PEK 95.523 0.01565 2990600.0 29215.0 29188.0 23435.0 30399.0 29704.0 25501.0 27930.0 25408.0 21546.0 18887.0 True False 34160.522477447914 32085.591743228124 23993.77927773242 28695.842584887756 23883.71443194815 24163.682668055164 25284.268204311 24741.06692200127 21861.069488972695 22311.06359059026 1.5311023761258602 1.4381022945387638 1.075420684464897 1.286170982767056 1.0704874886386482 1.083035892481892 1.133261446799636 1.1089147239235995 0.9798308987023213 1.0 14.445471669478229 -1.5228787452827985 0.4368993333524237 1.0468291249193569 11.905981997410349 0.7993639012006994 0.07915995952672066 34.56394842489132 0.42832735163259944 0.04956285271932996 331.9538960815579 0.029999999999830003 1.5228787452827985 10.859152872490991 FGLHGS(ph)SGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FGLHGSSGK 9 0 Q9NV70-2 Q9NV70-2 EXOC1 Exocyst complex component 1 1 FGLHGS(0.934)S(0.066)GK 67.214 0.039381 0.0 23338.0 29313.0 43586.0 53714.0 62007.0 51095.0 59240.0 47232.0 56248.0 45460.0 True False 27288.66245348893 32223.00091713191 44625.25554082551 50704.57872313759 49857.173470973925 48415.48825239322 53628.35833954115 45992.21004644066 57070.52058923864 53701.538138838005 0.508154205619545 0.6000386959834136 0.8309865431685214 0.944192298403964 0.9284123918773984 0.90156613628499 0.9986372867177908 0.8564412052320377 1.0627353064206575 1.0 15.712675790544008 -5.271834908752836 1.7228401771867927 0.951268774355038 0.49016793250836166 0.8976232820023807 0.05406825790665664 0.12089024712389644 0.6166769716201826 0.01468620423295766 0.06606212139397381 5.3476760552713476e-06 5.271834908752836 -0.4611008418466763 FGQAATMEGIGAIGGT(ph)PPAFNR ddPTM_PC-9_AZD4547_30min_R2 8 FGQAATMEGIGAIGGTPPAFNR 22 0 Q15233;Q15233-2 Q15233 NONO Non-POU domain-containing octamer-binding protein 1 FGQAATMEGIGAIGGT(1)PPAFNR;FGQAATMEGIGAIGGT(1)PPAFNR;FGQAATMEGIGAIGGT(1)PPAFNR;FGQAATMEGIGAIGGT(1)PPAFNR;FGQAAT(0.001)MEGIGAIGGT(0.999)PPAFNR;FGQAAT(0.011)MEGIGAIGGT(0.989)PPAFNR;FGQAATMEGIGAIGGT(1)PPAFNR;FGQAATMEGIGAIGGT(1)PPAFNR 149.18 2.7450999999999998e-06 459558600.0 186649.8 159766.7 198924.7 296010.1 230195.5 208778.6 153165.90000000002 241736.0 170878.0 195352.3 True False 246000.5538429817 211408.16136689798 196286.82850290995 227769.54475545586 198236.8282885635 195723.64113765737 166797.3683783349 204381.2557406595 179910.2622256489 188513.07543761207 1.304952207012266 1.1214509172699958 1.0412372088633746 1.2082426867564187 1.051581317785935 1.0382496847144782 0.8848053005932529 1.084175488974498 0.9543648991350192 1.0 17.524305068035673 -1.522878745280354 0.3321128525349755 0.9800079956881355 4.004851196551994 0.594628503728114 0.07312019968148903 43.37808460584707 0.6170108901449693 0.06718953226911123 80.71300383944728 0.02999999999999886 1.522878745280354 3.024843200863858 FGQAATMEGIGAIGGT(ph)PPAFNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 FGQAATMEGIGAIGGTPPAFNR 22 0 Q15233;Q15233-2 Q15233 NONO Non-POU domain-containing octamer-binding protein 1 FGQAAT(0.003)MEGIGAIGGT(0.997)PPAFNR;FGQAATMEGIGAIGGT(1)PPAFNR;FGQAAT(0.001)MEGIGAIGGT(0.999)PPAFNR;FGQAATMEGIGAIGGT(1)PPAFNR;FGQAATMEGIGAIGGT(1)PPAFNR;FGQAATMEGIGAIGGT(1)PPAFNR;FGQAAT(0.001)MEGIGAIGGT(0.999)PPAFNR 153.6 4.1283e-06 407035200.0 212037.3 194208.7 213952.5 224994.7 244433.6 204698.0 204159.2 174537.8 177793.6 144743.9 True False 247931.0269624294 213488.4562554159 219053.93901937487 212388.97640165922 196538.5907612793 193963.27652976586 184819.76259139148 169956.3676880853 180393.49504755434 170984.82327791766 1.4500177396413942 1.2485813194567164 1.2811308911512338 1.2421510420047253 1.1494505008893492 1.1343888469826306 1.0809132591316986 0.9939851059870927 1.0550263560780706 1.0 17.383508750697807 -5.0323439988903145 0.3110094531862527 0.9763711803185527 1.6776769532589715 0.9116490007658868 0.04036913423562993 1.7397470352182118 0.1548363748310168 0.04525105196574041 0.4584618508149893 9.28230856185036e-06 5.0323439988903145 0.7013057729404187 FGQAATMEGIGAIGGT(ph)PPAFNR ddPTM_PC-9_Lapatinib_30min_R1 8 FGQAATMEGIGAIGGTPPAFNR 22 0 Q15233;Q15233-2 Q15233 NONO Non-POU domain-containing octamer-binding protein 1 FGQAAT(0.002)MEGIGAIGGT(0.998)PPAFNR;FGQAATMEGIGAIGGT(1)PPAFNR;FGQAAT(0.109)MEGIGAIGGT(0.891)PPAFNR;FGQAAT(0.003)MEGIGAIGGT(0.997)PPAFNR;FGQAATMEGIGAIGGT(1)PPAFNR;FGQAATMEGIGAIGGT(1)PPAFNR;FGQAATMEGIGAIGGT(1)PPAFNR;FGQAAT(0.002)MEGIGAIGGT(0.998)PPAFNR 198.48 4.619399999999999e-19 272523120.0 191779.1 156872.38999999998 194401.2 149475.3 143091.9 148232.6 145612.15 119599.20000000001 162694.69999999998 111409.3 True False 189044.2948660207 156509.16161916577 178418.28374633295 160468.2121969834 134675.51577149957 141893.0372450677 153151.234641278 125156.21545034573 144370.30963485708 130666.24906143933 1.4467721865738412 1.1977780241137486 1.3654504130017584 1.2280769774108322 1.0306832616598267 1.0859195719190617 1.172079521233262 0.9578312406557046 1.1048783497793229 1.0 16.995527017255476 -6.082768285602075 3.4961867386401013 1.063851855810401 1.321643906272319 0.7120659606373065 0.08001670589418665 0.13494671549800344 3.1406086631133885 0.02331379036182635 0.0319794265811019 8.264787932086173e-07 6.082768285602075 0.257792050461918 FGS(ph)LTYSDPR ddPTM_PC-9_AZD4547_30min_R2 1 FGSLTYSDPR 10 0 Q6PJI9-3;Q6PJI9;Q6PJI9-4;H3BNY4 Q6PJI9-3 WDR59 WD repeat-containing protein 59 1 FGS(1)LTYSDPR 128.91 0.00026405 3664500.0 32447.0 27768.0 24532.0 27373.0 28311.0 39360.0 34785.0 32727.0 30797.0 33554.0 True False 42764.47106047373 36743.46296716413 24206.689651075965 21062.577758634212 24380.506333431902 36898.81297785399 37880.79761252595 27669.7941416445 32424.86654667839 32379.28467304272 1.3207355101355023 1.1347830360735176 0.7475980366925516 0.6504954624945684 0.7529661812983108 1.1395808570340034 1.1699084150572203 0.8545523602836386 1.0014077480122228 1.0 14.982783493353816 -6.775781756088146 24.99166569244586 1.032550515425999 0.9084783606381583 0.07035100601311373 0.2004562242004632 746.7923862540192 1301281.4661461206 0.07921292762169996 0.07017702331962171 1.6757847885168666e-07 6.775781756088146 -0.12407215478784073 FGS(ph)NINLEADES ddPTM_PC-9_AZD4547_30min_R2 1 FGSNINLEADES 12 0 Q9NQP4 Q9NQP4 PFDN4 Prefoldin subunit 4 1 FGS(0.827)NINLEADES(0.173) 96.70700000000001 0.0041995 2922600.0 16200.0 17800.0 15913.0 20009.0 22178.0 19283.0 17857.0 20233.0 16132.0 19040.0 True False 21351.263019067235 23553.501902028293 15701.983222630515 15396.234185968371 19098.96752014597 18077.230961685942 19446.238406407243 17106.454758086395 16984.70458586927 18373.415395324966 1.1620737113743136 1.2819337828731274 0.8546033976146762 0.8379625592031122 1.039489235354991 0.9838797290941135 1.0583899611476293 0.9310438146649128 0.9244173835089448 1.0 14.165332210457072 -5.256130692555439 24.993141652392076 0.9550044108701609 1.2220037657959302 0.6841599001245937 0.07290865665143262 253.2894631371578 1192469.7791742762 0.019799867182087625 0.049217389371563204 5.544588341480183e-06 5.256130692555439 0.2669993549257693 FGS(ph)NINLEADES ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 FGSNINLEADES 12 0 Q9NQP4 Q9NQP4 PFDN4 Prefoldin subunit 4 1 FGS(1)NINLEADES;FGS(1)NINLEADES;FGS(1)NINLEADES;FGS(0.999)NINLEADES(0.001) 123.38 0.00035731 8212900.0 72462.0 73901.0 64067.0 85177.0 81779.0 74350.0 76697.0 82911.0 70210.0 58316.8 True False 84728.38541026278 81237.40288530581 65594.60025545055 80404.80883756002 65754.99200546363 70450.95511430544 69431.70492180588 80734.67410146618 71236.68842572988 68889.1742044652 1.229923081365242 1.1792477384645472 0.9521757375224698 1.1671617458922654 0.9545039952184762 1.022670919311717 1.007875413279457 1.1719500927945974 1.03407667820632 1.0 16.071989663659547 -5.091017474172055 5.896517132510867 1.0451315181948075 1.218379297789316 0.4618120518340615 0.0721847559711271 0.17772264313000513 9.068413557445497 0.017892481217136626 0.04993761282438453 8.1092842886922e-06 5.091017474172055 0.17324777959450843 FGS(ph)NINLEADES ddPTM_PC-9_Lapatinib_30min_R1 2 FGSNINLEADES 12 0 Q9NQP4 Q9NQP4 PFDN4 Prefoldin subunit 4 1 FGS(1)NINLEADES;FGS(0.991)NINLEADES(0.009) 106.13 0.0017081 2761100.0 36466.0 32325.0 28193.5 30675.5 29093.0 31401.0 23129.0 26394.1 24935.4 25378.5 True False 35945.9881529546 32250.153448542067 25875.539260057227 32931.47860046819 27381.8069390387 30058.052429306175 24326.50644893385 27620.466242399296 22126.912670597238 29765.139910274393 1.207653928767413 1.0834873797253644 0.8693236228036494 1.1063774166605154 0.91992871599394 1.0098407909357978 0.8172817773497775 0.9279467970135497 0.7433834592176543 1.0 14.861336055282337 -1.5228787452881176 0.41281962592932875 0.8855885843301411 6.431108028428652 0.48455474870273907 0.09619186688958362 64.62512363881767 0.8389709944885784 0.06499811036806627 294.3791494609122 0.02999999999946257 1.5228787452881176 5.545519444098511 FGS(ph)TLQLDLEK ddPTM_PC-9_Lapatinib_30min_R1 1 FGSTLQLDLEK 11 0 E5RIQ4;E5RIK1;A0A0D9SF44;A0A0R4J2E2;Q9Y3T6-3;Q9Y3T6 E5RIQ4 R3HCC1 R3H and coiled-coil domain-containing protein 1 1 FGS(0.607)T(0.393)LQLDLEK 121.76 0.00073603 6965600.0 24321.0 34469.0 26664.0 25525.0 23633.0 26334.0 27442.0 23363.0 20864.0 16116.0 True False 23974.178080074835 34389.18914826903 24471.78884601649 27402.193648903893 22242.953404265685 25207.75620755228 28862.812485262755 24448.530270824733 18514.07661233992 18901.629126779837 1.2683657011399196 1.819376992195155 1.294692043837896 1.44972655346837 1.1767744068553254 1.3336287596415655 1.5270013125149042 1.2934615374600724 0.9794963433130305 1.0 14.206222964886592 FGSLT(ph)YSDPR ddPTM_PC-9_AZD4547_30min_R2 1 FGSLTYSDPR 10 0 Q6PJI9-3;Q6PJI9;Q6PJI9-4;H3BNY4 Q6PJI9-3 WDR59 WD repeat-containing protein 59 1 FGS(0.348)LT(0.551)Y(0.01)S(0.091)DPR 87.806 0.025408 2690200.0 30817.0 29869.0 24443.0 32414.0 30801.0 42041.0 28718.0 31196.0 32512.0 30154.0 True False 40616.16496657992 39523.570129869826 24118.869849227507 24941.453091307852 26524.81281396052 39412.169624033566 31273.846365862297 26375.37501276443 34230.51794543649 29098.317638163284 1.3958251975815483 1.358276812472262 0.8288750624398612 0.857144162128343 0.9115582950119585 1.3544483950626536 1.0747647597621157 0.9064226784772039 1.176374468486184 1.0 14.828648123568176 -5.190022793143243 8.324374268792477 1.0156473445690504 1.38045777710789 0.4812300198240954 0.1509183833501685 0.31925614515983824 34.28370428744255 0.0410601493626653 0.10949945663852519 6.45620343954913e-06 5.190022793143243 0.3648104325388397 FGSNINLEADES(ph) ddPTM_PC-9_AZD4547_30min_R2 1 FGSNINLEADES 12 0 Q9NQP4 Q9NQP4 PFDN4 Prefoldin subunit 4 1 FGS(0.001)NINLEADES(0.999) 123.96 0.00033655 2523800.0 33190.0 26809.0 31644.0 36637.0 34642.0 31946.0 32784.0 31669.0 27673.0 34282.0 True False 43743.72960511367 35474.48497143127 31224.379884177706 28190.905686007438 29832.55626444662 29948.41156988119 35701.71248897658 26775.283731223142 29135.738284450807 33081.797614628675 1.3222899829896282 1.072326400901037 0.9438537847281423 0.8521576129086015 0.9017815963922937 0.9052836825480757 1.079195057803914 0.8093660460392633 0.8807181104199449 1.0 15.013750010045577 -4.806880177924928 1.8217817509240815 0.9149947600444976 1.4418479094685877 0.7489472348682313 0.07158919854350776 0.39605953883790895 1.4245008111059887 0.01987506449712679 0.3571613801824444 1.5599828435423757e-05 4.806880177924928 0.52685314942409 FGSTGS(ph)TPPVSPTPSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FGSTGSTPPVSPTPSER 17 0 W0Z7M9;A0A499FIJ6;Q969V6;E7ER32;A0A087X287;A0A087WU73;A0A494BZX7;B0QY83 W0Z7M9 mkl1;MKL1 MKL/myocardin-like protein 1 1 FGS(0.001)T(0.018)GS(0.97)T(0.011)PPVS(0.001)PTPSER 104.95 0.00075423 9029700.0 36058.0 35171.0 37986.0 42835.0 32987.0 27711.0 24328.0 21877.0 22738.0 21492.0 True False 42161.907222037196 38662.54444295861 38891.73030270722 40435.09382294371 26523.434149160843 26257.786377572516 22023.475720532697 21302.751930597522 23070.500233930226 25388.32946942162 1.6606806396150688 1.5228471211359067 1.531874334211294 1.5926646088174021 1.044709703374 1.0342463220826756 0.867464546931233 0.8390765511474524 0.9087049331747861 1.0 14.631877849545916 -6.354015293480917 2.702316627542825 0.918146017287964 1.5785443780043897 0.9533062938362868 0.06826682713383436 0.05709237468744829 0.8132594778436897 0.024011219178371134 0.028403099261574406 4.425727870905778e-07 6.354015293480917 0.6603983607164258 FGSTGST(ph)PPVS(ph)PTPSER ddPTM_PC-9_AZD4547_30min_R2 1 FGSTGSTPPVSPTPSER 17 0 W0Z7M9;A0A499FIJ6;Q969V6;E7ER32;A0A087X287;A0A087WU73;A0A494BZX7;B0QY83 W0Z7M9 mkl1;MKL1 MKL/myocardin-like protein 1 2 FGSTGST(1)PPVS(1)PTPSER 133.25 0.00059579 7259100.0 21619.0 24832.0 28684.0 40271.0 38163.0 30292.0 28779.0 36721.0 31211.0 30148.0 True False 28493.3922968651 32858.458383773395 28303.631418207344 30987.143130747758 32864.72619133065 28397.83645135044 31340.275247689642 31046.613214634028 32860.749741480635 29092.527696337038 0.9794058664917117 1.129446665024934 0.9728831992061996 1.0651237820991837 1.1296621089225107 0.9761213170530361 1.0772620232526449 1.0671679524960296 1.1295254260638907 1.0 14.828361029598693 -4.715550724800606 24.097542988999347 1.060306172629986 0.9794040290520883 0.15256474009752008 0.05753820913074417 16692.726672537847 8764764.181768565 0.013635591815962116 8.865021411942239 1.9250821858704973e-05 4.715550724800606 -0.08090214357789771 FGSTGST(ph)PPVS(ph)PTPSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FGSTGSTPPVSPTPSER 17 0 W0Z7M9;A0A499FIJ6;Q969V6;E7ER32;A0A087X287;A0A087WU73;A0A494BZX7;B0QY83 W0Z7M9 mkl1;MKL1 MKL/myocardin-like protein 1 2 FGS(0.001)T(0.002)GS(0.004)T(0.993)PPVS(0.998)PT(0.002)PSER 153.92 0.00068912 4900200.0 17179.0 20883.0 25396.0 30023.0 30279.0 27399.0 30268.0 25293.0 27450.0 19099.0 True False 20087.06539928384 22956.126229061014 26001.536954866333 28340.90864587928 24346.0473096202 25962.14820681714 27400.79591865682 24629.08555014872 27851.40431970206 22561.49751239919 0.8903250056094252 1.0174912466003174 1.1524738967604695 1.2561625676799106 1.0790971342323474 1.150728057503676 1.2144936701829336 1.0916423227940981 1.2344661210717807 1.0 14.461575208900104 -4.999505223955951 2.476028637642065 1.1547305431388513 0.8831906710874843 0.5530930089392136 0.0736657884653578 0.23834678354441596 2.505612403610908 0.018435519809356687 0.11283564383103152 1.0011399131510809e-05 4.999505223955951 -0.271539872051367 FGSTGST(ph)PPVS(ph)PTPSER ddPTM_PC-9_Lapatinib_30min_R1 3 FGSTGSTPPVSPTPSER 17 0 W0Z7M9;A0A499FIJ6;Q969V6;E7ER32;A0A087X287;A0A087WU73;A0A494BZX7;B0QY83 W0Z7M9 mkl1;MKL1 MKL/myocardin-like protein 1 2 FGS(0.001)T(0.003)GS(0.014)T(0.983)PPVS(0.979)PT(0.009)PS(0.011)ER;FGST(0.001)GS(0.006)T(0.994)PPVS(0.998)PT(0.002)PSER;FGS(0.013)T(0.021)GS(0.036)T(0.93)PPVS(0.976)PT(0.019)PS(0.005)ER 140.68 0.0022233 18042500.0 81109.0 67203.0 73867.0 63951.0 80115.0 66307.0 58283.0 66675.0 76469.0 61576.0 True False 79952.37078643117 67047.39558243997 67793.9403948659 68654.16987428216 75402.79321215017 63471.20417916642 61300.60855909082 69772.9639090545 67856.25596573157 72219.32955513752 1.1070771672754132 0.9283857382150175 0.9387229265692234 0.9506342733612134 1.0440804930843641 0.8788672585323277 0.8488116538424724 0.9661258881638427 0.9395857921102015 1.0 16.14009740670435 -6.771645165915805 24.99977135837421 0.9196943396674258 0.9846913792628951 0.20686461173854942 0.06374985228731796 358.4808536915234 878117.8677817519 0.022567627115698888 0.020127323669507247 1.6918226465654267e-07 6.771645165915805 0.06499703959546932 FGSTGST(ph)PPVSPTPSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FGSTGSTPPVSPTPSER 17 0 W0Z7M9;A0A499FIJ6;Q969V6;E7ER32;A0A087X287;A0A087WU73;A0A494BZX7;B0QY83 W0Z7M9 mkl1;MKL1 MKL/myocardin-like protein 1 1 FGST(0.018)GS(0.144)T(0.836)PPVS(0.002)PTPSER;FGS(0.001)T(0.006)GS(0.255)T(0.726)PPVS(0.012)PTPSER;FGST(0.001)GS(0.015)T(0.93)PPVS(0.053)PTPSER 140.27 0.00010049 15098900.0 61469.0 59463.0 56512.0 70510.0 62058.0 49411.0 41710.0 37266.9 37641.8 34990.9 True False 71874.48763190978 65366.09366272351 57859.46040295345 66559.55329650418 49898.18038708047 46819.80017690577 37758.926845750524 36288.683362544456 38192.24011371077 41334.47318218802 1.7388509420481053 1.5813941398167202 1.3997870529988135 1.6102673669779886 1.207180751213318 1.132705864437665 0.9134972321849192 0.8779278062308071 0.9239803286078578 1.0 15.335057878963674 -6.554229672786092 1.088716093675882 0.9058399984122986 1.6134783607617298 0.9103265606658187 0.09160438912635696 0.133695838878832 0.3377425572737862 0.04480481942401604 0.04990213231639693 2.7910674196175795e-07 6.554229672786092 0.7076383623494312 FGSTGST(ph)PPVSPTPSER ddPTM_PC-9_Lapatinib_30min_R1 2 FGSTGSTPPVSPTPSER 17 0 W0Z7M9;A0A499FIJ6;Q969V6;E7ER32;A0A087X287;A0A087WU73;A0A494BZX7;B0QY83 W0Z7M9 mkl1;MKL1 MKL/myocardin-like protein 1 1 FGSTGS(0.001)T(0.924)PPVS(0.073)PTPS(0.001)ER;FGS(0.02)T(0.057)GS(0.028)T(0.825)PPVS(0.069)PTPSER 160.63 7.3033e-05 20446800.0 146506.0 117477.0 124837.0 100975.0 90401.0 83883.0 64773.0 70766.0 74741.0 65063.0 True False 144416.79757408975 117204.98922426543 114573.38374475532 108401.03834272578 85083.79091520434 80295.51963082352 68126.62900327682 74054.0467039843 66322.88152237819 76309.0528590019 1.8925250958222768 1.5359250945078293 1.5014389440327005 1.4205527952629817 1.114989476706201 1.0522410726180484 0.892772566960778 0.9704490349371231 0.8691351686008291 1.0 16.219566599650484 -5.770169789756525 0.6341412581368485 0.8984295885933808 1.918110758852762 0.9411303751852825 0.07867024928652655 0.27607427628258746 0.18419535376622795 0.045931603527525365 0.17542377172546622 1.6975798447673358e-06 5.770169789756525 1.019681170259381 FGT(ph)FGGLGSK ddPTM_PC-9_AZD4547_30min_R2 2 FGTFGGLGSK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 FGT(1)FGGLGSK;FGT(1)FGGLGSK 124.21 0.0010279999999999998 134025000.0 166886.0 174793.0 179940.0 184080.0 206609.0 200060.0 240190.0 139212.0 196594.0 214642.0 True False 219952.2765555591 231291.4189865862 177553.87802929274 141643.20000764952 177924.90668093832 187550.2165739196 261566.44469031447 117699.98417351485 206985.5574853943 207127.44891194045 1.0619175667493066 1.1166623265124025 0.8572204165213235 0.6838456262157154 0.8590117225678887 0.9054821925299528 1.2628284955197733 0.5682490891081974 0.9993149559496266 1.0 17.660159229275095 -5.261926908241923 24.910452883178948 0.8816883766450271 1.089289957156548 0.16377499472753976 0.17710588409680872 66.71903857405286 3409270.199757275 0.045629780636017685 0.10540773193335233 5.4710803342397874e-06 5.261926908241923 0.2076015805115209 FGT(ph)FGGLGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FGTFGGLGSK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 FGT(1)FGGLGSK 101.72 0.008541799999999999 99105000.0 197860.0 174150.0 126660.0 179590.0 134120.0 100460.0 120730.0 75247.0 79387.0 91790.0 True False 231353.79008686743 191438.46108274578 129680.05476072473 169528.15453863618 107840.14878847575 95191.70075027736 109293.58039049302 73271.84598078659 80547.88468955149 108430.80039075989 2.1336538073418354 1.7655358107921846 1.1959706494223723 1.5634686263284543 0.9945527322480737 0.8779027767684843 1.0079569642262518 0.6757475340653353 0.7428505959494467 1.0 16.72641509514446 -4.1342056850345665 0.43027750240162704 0.7778231292458053 4.0628672805883514 0.8600044878338738 0.1685857828019434 3.0704043515728583 0.29075813555184826 0.12116634326240223 5.777109690051044 7.341660793954329e-05 4.1342056850345665 3.285044151342546 up FGT(ph)FGGLGSK ddPTM_PC-9_Lapatinib_30min_R1 1 FGTFGGLGSK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 FGT(0.992)FGGLGS(0.008)K 103.46 0.006898100000000001 108200000.0 173350.0 175380.0 116060.0 123840.0 117290.0 92020.0 70257.0 57041.0 56750.0 51621.0 True False 170877.997211503 174973.91838531505 106517.99480455554 132947.60671812977 110391.23280101223 88084.51910909705 73894.56368985883 59691.33309840834 50358.217396007065 60543.62106934114 2.8223947328124783 2.89004713122322 1.759359498543365 2.1958978397718187 1.823333835195952 1.4548934727279208 1.2205177421619156 0.9859227453548464 0.831767517478536 1.0 15.885687343822132 -5.700457315647073 0.407380926349346 0.800828272323962 3.549267019341763 0.9000981724009038 0.22314631025796322 0.7889657410376109 0.177099586865008 0.20592994386591015 0.9881012408594133 1.993162393217981e-06 5.700457315647073 2.7484387470178007 up FGTFGGLGS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 2 FGTFGGLGSK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 FGT(0.06)FGGLGS(0.94)K;FGT(0.107)FGGLGS(0.893)K 72.531 0.030319 22610000.0 51164.0 51521.0 40803.0 58595.0 33904.0 30684.0 21608.0 22495.0 36282.0 33979.0 True False 50434.391977671505 51401.70628994081 37448.33484413482 62904.27176718993 31909.833377828636 29371.71684789756 22726.756511243995 23540.19982203495 32195.539093602256 39852.22487582849 1.265535164844997 1.2898076945540224 0.9396799039656203 1.5784381414886364 0.8007039375405828 0.7370157359950145 0.5702757269401142 0.5906872174735908 0.8078730659057826 1.0 15.282372649002928 -6.417913524705722 6.6531064531175605 0.7116328598795056 1.2450696873013187 0.6556553137295831 0.1830505498614671 0.14560476155112317 7.981894817169754 0.055100096192717704 0.06238995076084544 3.8202032990388676e-07 6.417913524705722 0.5334368274218131 FGTSHMMVSFR ddPTM_PC-9_AZD4547_30min_R2 1 FGTSHMMVSFR 11 0 A0A1B0GU80;Q96N23;Q96N23-2 A0A1B0GU80 CFAP54 Cilia- and flagella-associated protein 54 0 82.279 0.017609 0.0 4067.3 5068.9 6566.8 7811.7 6665.7 7962.8 3984.6 7529.8 6046.5 7181.5 False True 5360.616794904455 6707.322797257936 6479.719941329106 6010.833254561905 5740.282613357247 7464.884857216872 4339.221680806985 6366.24242759052 6366.105645825596 6930.07787087848 0.7735290850671097 0.9678567719193166 0.9350140160124514 0.8673543597281327 0.8283143018463066 1.0771718581382401 0.6261432788571148 0.9186393784033358 0.9186196409967046 1.0 12.758655848178837 FGYVDFESAEDLEK ddPTM_PC-9_AZD4547_30min_R2 1 FGYVDFESAEDLEK 14 0 P19338 P19338 NCL Nucleolin 0 156.69 2.5299e-12 0.0 2432.5 1325.8 4497.4 5006.4 4348.2 5865.8 3994.0 3587.5 4341.0 4635.9 False True 3205.984400856855 1754.3389225679282 4437.761537451042 3852.2518281089547 3744.5274853953806 5499.010598716872 4349.458262596768 3033.134307548803 4570.456397672855 4473.598552058137 0.7166455289963155 0.3921538560407531 0.9919892198215668 0.8611080729040106 0.8370280528798594 1.2292141404120807 0.9722504627948216 0.678007709510137 1.0216509918106436 1.0 12.127220083540005 -5.27174685754254 24.975537771867597 0.9411198102190014 0.5543996895622533 0.513334365145081 0.15349909427366024 487.3065907000801 1180769.5987728054 0.040510414851165584 0.08584548065195133 5.348760381932361e-06 5.27174685754254 -0.3867201206567481 FGYVDFESAEDLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FGYVDFESAEDLEK 14 0 P19338 P19338 NCL Nucleolin 0 161.99 0.0024432 2507400.0 5589.4 4901.1 5027.7 5169.0 6479.4 6360.2 4975.6 4957.2 5299.2 6059.6 False True 6535.575024317889 5387.648817758506 5147.579435658432 4879.397688124106 5209.8080827620815 6026.659915507804 4504.275147775504 4827.078752587559 5376.690774898544 7158.15751223279 0.9130247571597927 0.7526586008412628 0.7191207272069075 0.6816555349313782 0.7278141161128243 0.8419289328585832 0.6292506332918789 0.6743465402009413 0.751127753993979 1.0 12.805372574660716 -8.585179965034795 20.203350292407944 1.0000000005175418 0.7374157047926811 0.49125927252790824 0.07823515545543884 5378.835271427242 1744273.1738451526 0.07697385297649721 0.019874563428913805 2.599082319760198e-09 8.585179965034795 -0.26258429572486064 FGYVDFESAEDLEK ddPTM_PC-9_Lapatinib_30min_R1 2 FGYVDFESAEDLEK 14 0 P19338 P19338 NCL Nucleolin 0 ; 204.49 4.999399999999999e-10 5617200.0 17412.7 15911.400000000001 17519.6 16219.8 16976.8 12393.8 15469.5 15663.5 18285.3 15502.400000000001 False True 17164.391704901915 15874.558130893512 16079.206115611702 17412.658199666635 15978.258001672984 11863.746065358908 16270.43501715517 16391.283392418052 16225.81696125476 18181.969184350433 0.944033703438219 0.8730934460364748 0.8843489917171007 0.9576882472473907 0.8787968915614364 0.6525006144862604 0.8948664939526706 0.9015130993911452 0.892412521258733 1.0 14.150220837533004 -8.836413564846596 1.3590961895492544 0.9994659104699114 0.8687993665398649 0.18808606536333672 0.07884663306346812 2.044205946606983 6.192210514928169 0.08009962541443988 0.023744549452623616 1.4574257389988245e-09 8.836413564846596 -0.1306665439300465 FHALS(ph)SPQSPFPSTPTSR ddPTM_PC-9_Lapatinib_30min_R1 2 FHALSSPQSPFPSTPTSR 18 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 FHALS(0.543)S(0.455)PQS(0.002)PFPSTPTSR;FHALS(0.815)S(0.18)PQS(0.005)PFPSTPTSR 110.22 0.00023056 18829700.0 105899.0 79791.0 112115.0 74570.0 90396.0 83643.0 67469.0 84923.0 109898.0 73039.0 True False 104388.86084050161 79606.24884184447 102897.33747641562 80054.12655822754 85079.08500537397 80065.78387135628 70962.21469164755 88868.83260665376 97520.12996275567 85663.69383165009 1.218589301620019 0.9292880715404361 1.2011779188349478 0.9345163975248755 0.9931755356309405 0.9346524798324124 0.8283814474671789 1.0374153697049597 1.1384067812252685 1.0 16.386396267351678 -4.750319827731619 24.91760772049186 0.9975112881326859 1.2185897993389208 0.29270458244183006 0.1020430688601593 633.9998200578877 1420624.165891627 0.02597847116243418 0.3849502988058127 1.776970312813201e-05 4.750319827731619 0.2210785112062349 FHALSS(ph)PQSPFPSTPTSR ddPTM_PC-9_AZD4547_30min_R2 3 FHALSSPQSPFPSTPTSR 18 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 FHALS(0.233)S(0.766)PQS(0.001)PFPSTPTSR;FHALS(0.236)S(0.753)PQS(0.012)PFPSTPTSR;FHALS(0.023)S(0.974)PQS(0.003)PFPSTPTSR 176.25 2.0415e-08 45616200.0 81143.0 80003.0 158588.0 254389.0 216590.0 178588.0 139930.0 208600.0 141035.0 187237.0 True False 106944.78612075125 105862.40520606579 156485.0195004414 195743.5463208711 186520.2171155384 167420.86412827726 152383.4989196707 176365.66315113066 148489.82217134113 180681.88962050743 0.5918954375857546 0.5859049040742952 0.8660802686373961 1.0833600795962353 1.0323127431714014 0.9266056740933871 0.8433800379203868 0.9761114604322421 0.8218301373935128 1.0 17.463092381502207 -5.3342771023298505 3.7548613491646434 0.9523603085307965 0.5838094920678254 0.7831424322465097 0.07570020651288023 0.10091751462472501 2.7405915935743765 0.021424112550513883 0.05095751248770783 4.6315131096096414e-06 5.3342771023298505 -0.36855081646297105 FHALSS(ph)PQSPFPSTPTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FHALSSPQSPFPSTPTSR 18 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 FHALS(0.323)S(0.675)PQS(0.001)PFPSTPTSR 65.189 0.0086123 15411000.0 57470.0 50376.0 71079.0 93193.0 90356.0 82422.0 80415.0 80626.0 71005.0 54556.0 True False 67198.53591576003 55376.99635661435 72773.79292860853 87971.69834578247 72651.39042597318 78099.64522436155 72797.50904581715 78509.65293030845 72043.3137967375 64446.57093494159 1.0427014958421377 0.8592698657701598 1.1292112500767995 1.3650330354207572 1.127311963569238 1.2118510588127744 1.1295792466492247 1.2182130374254272 1.1178766030773735 1.0 15.975815977441814 -5.408375309603929 5.892934664159744 1.1798905099293857 0.954175440916778 0.42754299552224917 0.09769146310492155 0.18044711278345635 8.071895704995692 0.02422147000894075 0.05119734666651613 3.905032839085479e-06 5.408375309603929 -0.22571506901260774 FHALSS(ph)PQSPFPSTPTSR ddPTM_PC-9_Lapatinib_30min_R1 1 FHALSSPQSPFPSTPTSR 18 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 FHALS(0.002)S(0.693)PQS(0.294)PFPS(0.009)T(0.002)PT(0.001)SR 142.95 9.9562e-05 7056200.0 50768.0 36362.0 52999.0 35098.0 50078.0 44765.0 34758.0 37826.0 42867.0 30675.0 True False 50044.03901028901 36277.806023074605 48641.62680205627 37679.22400349571 47132.51049713608 42850.50530231173 36557.599167799846 39583.53405060208 38038.86705047813 35977.13287813177 1.3909957522131404 1.0083573403684314 1.3520150971124896 1.0473103604761826 1.3100685554013383 1.1910483652897712 1.0161343120819086 1.100241483519172 1.0573067948279882 1.0 15.134792598175624 -7.200420245984244 6.081533687570312 1.0519498050570082 1.2108496790419527 0.34416412176491895 0.1168584860461304 0.26991415016661696 20.637918540665975 0.041676042495307576 0.03195106285100564 6.303470925597772e-08 7.200420245984244 0.15889987398494454 FHALSSPQS(ph)PFPSTPTSR ddPTM_PC-9_AZD4547_30min_R2 2 FHALSSPQSPFPSTPTSR 18 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 FHALSSPQS(1)PFPSTPTSR;FHALS(0.001)S(0.002)PQS(0.997)PFPSTPTSR 109.32 0.00014256 35922000.0 86814.0 75666.0 134683.0 228150.0 193583.0 147063.0 99690.0 165341.0 134481.0 157375.0 True False 114419.04615662358 100123.55477072315 132897.01541969116 175553.54238236224 166707.34193581075 137867.1273618431 108562.21687488057 139791.34760820286 141589.39111159698 151865.34915122212 0.753424311708454 0.6592916378246605 0.8750976846427095 1.155981554472655 1.0977312656741038 0.9078247811787526 0.714858376065617 0.9204953492649834 0.9323350711860366 1.0 17.21243320464287 -5.422579886887001 4.926435813077761 0.955415291014988 0.7110498225624111 0.4375216091967541 0.11385080485994276 0.23037970047174175 8.747897292289545 0.034215284311723354 0.07318573347098907 3.779376106614718e-06 5.422579886887001 -0.2443654684525769 FHALSSPQS(ph)PFPSTPTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FHALSSPQSPFPSTPTSR 18 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 FHALS(0.079)S(0.023)PQS(0.878)PFPS(0.007)T(0.007)PT(0.003)S(0.002)R;FHALSSPQS(1)PFPSTPTSR 106.35 0.00018192 13982000.0 35634.0 37344.0 55392.0 66020.0 82725.0 93531.0 81315.0 75949.0 76164.0 73643.0 True False 41666.13239641889 41051.26552210194 56712.7553553298 62321.11343972788 66515.63009638127 88626.06970808464 73612.25453038113 73955.41922461736 77277.75441186837 86993.89294233269 0.47895468276191433 0.4718867512839594 0.6519165131847137 0.7163849246410879 0.7646011443639354 1.0187619694963403 0.8461772664798195 0.8501219651549748 0.8883124067467006 1.0 16.40862650544115 -5.758852609588761 0.9157542162119208 0.9094292355954228 0.42981652115822233 0.8724506685933353 0.0650164993879367 0.2492991131842607 0.3845749293112396 0.027635316589515863 0.08879885531352513 1.7423981063237275e-06 5.758852609588761 -0.47961271443720044 FHDFDHR ddPTM_PC-9_AZD4547_30min_R2 2 FHDFDHR 7 0 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3;K7EII0 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 0 ; 127.12 0.0037961999999999996 25500000.0 58479.0 56241.0 80444.0 88307.0 70826.0 69367.0 62607.0 88502.0 47645.0 69714.0 False True 77074.10556123659 74419.80339730186 79377.25999882405 67949.18547954965 60993.03244575065 65029.47052425804 68178.90171417018 74826.04947364017 50163.417430804715 67273.33407929013 1.1456858295501604 1.106230342465095 1.1799216002178206 1.0100463491145384 0.90664500697799 0.9666455723394441 1.0134610190987818 1.1122690810217346 0.745665695291403 1.0 16.037747139732424 -5.886747741743526 4.912539266937653 0.9657265194704544 1.1392015817628804 0.46286010780660825 0.08940165288319858 0.19403977129352984 7.5302926650121 0.024852392610929207 0.03771006669778136 1.2979329513706969e-06 5.886747741743526 0.17347506229242604 FHDFDHR ddPTM_PC-9_Lapatinib_30min_R1 2 FHDFDHR 7 0 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3;K7EII0 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 0 ; 139.31 0.0024265000000000003 16174800.0 59905.0 41540.0 50830.0 51378.0 52353.0 45754.0 48694.0 46807.0 56229.0 37855.0 False True 59050.743714768454 41443.81668221001 46650.953609474156 55156.50951198366 49273.699469958185 43797.20807778336 51215.13705842812 48981.824097354496 49895.89790238024 44398.1863113831 1.3300260353119118 0.9334574252999243 1.0507400748825966 1.2423144748559758 1.1098133406707442 0.9864639012642358 1.153541198715526 1.1032393024756557 1.1238273913361998 1.0 15.438213122498315 -6.5337226217453175 24.96618522503032 1.0807929613663896 1.1253712229036723 0.06644653299454062 0.1100152766666942 927.3317389410115 2135007.2103805705 0.03613886325098217 0.036166894946463655 2.9260205925922974e-07 6.5337226217453175 0.044578261537282726 FHDT(ph)SSPLLISGTSAAELPWAVKPEDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FHDTSSPLLISGTSAAELPWAVKPEDK 27 1 P42566;B1AUU8 P42566 EPS15 Epidermal growth factor receptor substrate 15 1 FHDT(0.379)S(0.379)S(0.241)PLLISGTSAAELPWAVKPEDK 99.971 1.1126e-09 3721500.0 12010.0 15416.0 13985.0 27349.0 30776.0 23044.0 27347.0 22125.0 20598.0 17788.0 True False 14043.055791687462 16946.398599205317 14318.455438407844 25816.724196654315 24745.66372736455 21835.532073356466 24756.49418486548 21544.242193375238 20899.20678241247 21012.823590269483 0.6683088415680819 0.806478887827944 0.6814151071557258 1.2286175670655417 1.177645813331991 1.0391526859563966 1.178161234662894 1.0252902043755718 0.9945929775991826 1.0 14.358982416190306 -5.753364040509693 24.999974027779853 1.097942979304948 0.7275086423872832 0.8049793723673959 0.08410575942127077 75.84701572425759 234807.8076242981 0.02332418463151111 0.03951063025357356 1.764558087564678e-06 5.753364040509693 -0.3704343369176648 FHDTS(ph)SPLLISGTSAAELPWAVKPEDK ddPTM_PC-9_Lapatinib_30min_R1 1 FHDTSSPLLISGTSAAELPWAVKPEDK 27 1 P42566;B1AUU8 P42566 EPS15 Epidermal growth factor receptor substrate 15 1 FHDT(0.158)S(0.421)S(0.421)PLLISGTSAAELPWAVKPEDK 85.913 3.4204e-07 7083800.0 37757.0 34689.0 52620.0 38014.0 52993.0 54061.0 38622.0 51534.0 55456.0 39347.0 True False 37218.57825621421 34608.67975178582 48293.786719073956 40809.67637098658 49876.05592824661 51748.93705234613 40621.65818110266 53928.457774116396 49209.96130243113 46148.07652341811 0.8065033487869734 0.7499484780091202 1.0464962000001667 0.8843202023875788 1.0807829856773492 1.1213671500714841 0.8802459656252187 1.1685960030587643 1.0663491310945377 1.0 15.493982896370516 -5.2987377583036865 1.0426001673569576 1.0514533885029502 0.7235390753964773 0.5102817971736539 0.09391820030739655 0.7165487477015493 1.0911803879762416 0.031811118790915714 0.21658166083348335 5.026460125668438e-06 5.2987377583036865 -0.3279143131064729 FHDTS(ph)SPLMVTPPSAEAHWAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FHDTSSPLMVTPPSAEAHWAVR 22 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 FHDT(0.118)S(0.403)S(0.403)PLMVT(0.076)PPSAEAHWAVR;FHDT(0.12)S(0.44)S(0.44)PLMVTPPSAEAHWAVR 96.181 6.0133e-05 25707200.0 8910.8 12869.2 23597.1 26338.8 27621.0 24397.2 25050.4 19356.5 23876.1 13754.6 True False 10419.222443677649 14146.769126420155 24159.744356500083 24863.122427541737 22208.863329007545 23117.767883184017 22677.444762809606 18848.41238490703 24225.242793356585 16248.20009864631 0.6412539469246017 0.8706668455910245 1.4869181946197787 1.5302077938843923 1.3668506784857872 1.4227894623915933 1.3956896533234433 1.1600307892858455 1.4909493141566412 1.0 13.98799229137808 -5.118288477877136 3.8676840725238084 1.3718137625770657 0.6831987470842117 0.7078704566179537 0.15671285842007748 0.11151979385286873 2.84805046780989 0.03913609216139127 0.12510961452012337 7.6157297104593224e-06 5.118288477877136 -0.688615015492854 FHDTS(ph)SPLMVTPPSAEAHWAVR ddPTM_PC-9_Lapatinib_30min_R1 1 FHDTSSPLMVTPPSAEAHWAVR 22 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 FHDT(0.112)S(0.444)S(0.444)PLMVTPPSAEAHWAVR 60.032 0.034205 0.0 8099.0 2889.9 7507.7 5373.1 9513.3 4087.9 2773.7 10355.0 7324.5 7172.5 True False 7983.506774825305 2883.2086141049253 6890.4458865600855 5768.25569813616 8953.746397867426 3913.0700463603316 2917.3086141816675 10836.131102786028 6499.537679595658 8412.257068244502 0.9490326686475512 0.34273900461135137 0.8190959727765437 0.6856965557924752 1.0643690896783216 0.4651629181818292 0.3467926135060993 1.28813599190774 0.7726270876969292 1.0 13.03827722239402 -7.7670795568890085 24.999999241005394 1.022786061026984 0.6690665405613642 0.28891414730292264 0.2535482442574874 181.88340428883697 806176.8895127691 0.1318462309674878 0.06610275063315667 1.709702092048347e-08 7.7670795568890085 -0.35371952046561994 FHDTSS(ph)PLMVTPPSAEAHWAVR ddPTM_PC-9_AZD4547_30min_R2 2 FHDTSSPLMVTPPSAEAHWAVR 22 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 FHDT(0.091)S(0.335)S(0.57)PLMVT(0.004)PPSAEAHWAVR;FHDT(0.037)S(0.133)S(0.828)PLMVT(0.001)PPSAEAHWAVR 94.18799999999999 7.1068e-05 72119000.0 7354.2 2947.9 27020.0 64474.0 43852.0 40095.0 19353.8 47678.0 28260.0 37282.0 True False 9692.682623137298 3900.7510256735522 26661.697145445632 49610.515413370216 37763.90674061868 37587.85331166301 21076.25070672142 40310.4606314458 29753.765906066546 35976.76852775761 0.26941504253387794 0.10842416329482056 0.7410809318484232 1.3789597410643923 1.0496747842008718 1.044781253287448 0.5858294552069121 1.1204580700555293 0.8270271934821007 1.0 15.134777987529983 -5.399430876820428 4.085375665459285 0.9966318993159577 0.19445159088553327 0.7252687934073213 0.1967080171295108 0.11489929523283712 3.2067320073846566 0.05383664205726866 0.11940935209338704 3.9862921388860485e-06 5.399430876820428 -0.8021803084304244 down FHDTSS(ph)PLMVTPPSAEAHWAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FHDTSSPLMVTPPSAEAHWAVR 22 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 FHDT(0.063)S(0.211)S(0.721)PLMVT(0.004)PPSAEAHWAVR 76.329 0.00031693 18965000.0 5381.7 5936.1 13231.0 14592.0 15808.0 14002.0 11507.0 12662.0 13493.0 9688.9 True False 6292.715516579882 6525.396777681801 13546.47721884693 13774.457547902291 12710.535878677501 13267.710470887752 10416.973656534434 12329.63591649796 13690.309598751901 11445.420872709807 0.5498020200885828 0.5701316579140225 1.1835717855642018 1.2034906973797517 1.1105345989490176 1.1592156040782187 0.9101433466175475 1.0772549173701822 1.1961385912330016 1.0 13.482482894413979 -5.255835900568209 24.95945256508944 1.106488853512091 0.559966756123999 0.8603834502530118 0.08782790423915027 150.89149579345977 672107.3488416538 0.02359955395340043 0.058830391422279436 5.5483531949269305e-06 5.255835900568209 -0.5465220973880919 FHDTSS(ph)PLMVTPPSAEAHWAVR ddPTM_PC-9_Lapatinib_30min_R1 2 FHDTSSPLMVTPPSAEAHWAVR 22 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 FHDT(0.163)S(0.163)S(0.674)PLMVTPPSAEAHWAVR;FHDT(0.065)S(0.213)S(0.721)PLMVT(0.001)PPSAEAHWAVR 89.39200000000001 8.1575e-05 38898000.0 29094.0 18923.8 42106.0 27528.5 33123.0 37631.0 19867.1 28804.0 47960.0 17449.8 True False 28679.114224813835 18879.983103774808 38644.20721386026 29553.03772238394 31174.77026232357 36021.60985214553 20895.72122753311 30142.338994171794 42558.23975881055 20465.97467960304 1.4013070314895013 0.9225059348182973 1.8882172883939972 1.444008320397138 1.5232487458021344 1.7600730195393852 1.0209980982903477 1.4728025156902245 2.079463129661021 1.0 14.320939755440897 -5.249439475518701 24.77815162166031 1.528127297509894 1.1619065314878012 0.15407539365726763 0.33886860661067436 1213.1956806886228 2505069.7757273484 0.0830001980411139 0.2158826231234622 5.630675825836592e-06 5.249439475518701 -0.36622076602209286 FHFPPLDTHS(ph)PTNDVQPGR ddPTM_PC-9_AZD4547_30min_R2 4 FHFPPLDTHSPTNDVQPGR 19 0 P41162 P41162 ETV3 ETS translocation variant 3 1 FHFPPLDT(0.031)HS(0.899)PT(0.07)NDVQPGR;FHFPPLDT(0.044)HS(0.925)PT(0.031)NDVQPGR;FHFPPLDT(0.353)HS(0.538)PT(0.11)NDVQPGR;FHFPPLDT(0.002)HS(0.897)PT(0.1)NDVQPGR 116.35 5.8958e-05 33567700.0 93514.0 99562.0 142687.0 200345.0 158153.0 153584.0 135444.0 168899.0 123389.0 147664.0 True False 123249.50678796605 131743.4694589743 140794.87714997024 154158.55554939454 136196.18586949463 143980.3682009842 147498.25361020447 142799.54046290903 129911.0906363638 142494.32830542373 0.8649432454868791 0.9245523735975937 0.98807355229037 1.0818574843131272 0.9558007500310497 1.0104287652233799 1.0351166629878439 1.002141924953189 0.9116930630243129 1.0 17.120544971338887 -5.0657758170322245 2.494982551527819 1.001788195162993 0.8662589872329594 0.5104862343841101 0.042439344138255584 0.26169278489251335 2.8891708322245977 0.011440286663813937 0.05745940160428394 8.594570590614607e-06 5.0657758170322245 -0.13552920793003365 FHFPPLDTHS(ph)PTNDVQPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FHFPPLDTHSPTNDVQPGR 19 0 P41162 P41162 ETV3 ETS translocation variant 3 1 FHFPPLDT(0.255)HS(0.702)PT(0.043)NDVQPGR 91.565 0.0008026 6971300.0 8544.8 8460.4 14126.0 19077.0 14911.0 16762.0 18488.0 17675.0 15416.0 13853.0 True False 9991.265872507156 9300.29259916429 14462.817413153327 18008.17753846849 11989.296589509118 15882.971212185434 16736.68279847125 17211.0499782105 15641.429835793326 16364.439239712347 0.6105474025813782 0.5683233298086278 0.8837954787998928 1.1004457454776213 0.732643289139669 0.9705783974339608 1.0227471014011629 1.0517347845591705 0.9558182597443082 1.0 13.998276545943915 -5.345027035880433 3.9746896266931713 0.9710899443802028 0.5868849784927122 0.7278034155023921 0.09294321731086559 0.11108910900051047 3.2401888629582443 0.0252262633808487 0.05821810763053341 4.518278161265699e-06 5.345027035880433 -0.38420496588749065 FHFPPLDTHS(ph)PTNDVQPGR ddPTM_PC-9_Lapatinib_30min_R1 3 FHFPPLDTHSPTNDVQPGR 19 0 P41162 P41162 ETV3 ETS translocation variant 3 1 FHFPPLDT(0.329)HS(0.639)PT(0.032)NDVQPGR;FHFPPLDT(0.065)HS(0.841)PT(0.093)NDVQPGR;FHFPPLDT(0.007)HS(0.988)PT(0.005)NDVQPGR 98.376 0.00031506 21443500.0 82536.0 76424.0 87394.0 76277.0 105073.0 112773.0 95791.0 99905.0 117004.0 92244.0 True False 81359.02150475142 76247.04492347673 80208.80267059582 81886.66503261276 98892.81272146614 107949.96167670285 100750.58927103734 104546.95102113373 103825.77741325837 108188.25249259624 0.7520134546060734 0.7047626998938228 0.7413818120048185 0.75689054168073 0.9140808770178979 0.9977974427869635 0.9312525801073653 0.9663429125846016 0.959676998390963 1.0 16.72318432858504 -6.303068338638885 2.7585675660078683 0.9665234249969686 0.7310038726532286 0.9619504895609206 0.02196108906424698 0.0463054885706659 0.6993200625078246 0.006931273731749728 0.008459674956422325 4.976587694573973e-07 6.303068338638885 -0.23551955234374 FHGTVK ddPTM_PC-9_AZD4547_30min_R2 1 FHGTVK 6 0 P04406;P04406-2 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 126.05 0.010478 2417700.0 17624.0 11120.0 27325.0 19222.0 25111.0 23341.0 10970.0 28286.0 42379.0 86995.0 False True 23228.06539802721 14714.322536548021 26962.65264616216 14790.664876939585 21624.77109741119 21881.48358018521 11946.308748294081 23915.048647616844 44619.067421556756 83949.33152921725 0.2766914872924634 0.1752762323238623 0.32117769319912015 0.17618561824750117 0.2575931303262972 0.2606510758524587 0.1423037983826751 0.28487479545079625 0.5314999727666418 1.0 16.35723121688182 -8.6029599289592 1.892741538912574 0.9984384306284337 0.22997098527747978 0.953460299706712 0.05221146089809728 0.07794748683204322 0.6154578118074673 0.04818596624777479 0.013534461739790947 2.49482490628656e-09 8.6029599289592 -0.7684674453509539 down FHGTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FHGTVK 6 0 P04406;P04406-2 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 103.28 0.029962 3594900.0 3094.0 14729.0 14756.0 15399.0 62960.0 53876.0 14367.0 38393.0 53999.0 72824.0 False True 3617.753090714488 16191.197779430137 15107.839002441639 14536.243954231595 50623.43996214166 51050.64771672249 13006.053751927546 37385.22443074602 54788.633218928655 86026.41472553297 0.04205397960913423 0.18821193270797237 0.1756186056415713 0.16897419241066175 0.5884639052278954 0.5934299119590121 0.15118674645948366 0.43457843210162217 0.6368815135877931 1.0 16.392492092181314 -9.327867506089667 0.18591871785624187 1.373471442287002 1.692768367949134e-15 0.7147880310766783 0.1537484242807763 5.780636664702222 0.44210932107696577 2.1263682289627113 0.757632949179805 4.700374850657899e-10 9.327867506089667 -1.3734714422870002 down FHGTVK ddPTM_PC-9_Lapatinib_30min_R1 1 FHGTVK 6 0 P04406;P04406-2 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 96.04799999999999 0.029031 2950800.0 17844.0 15975.0 15348.0 23018.0 22725.0 17100.0 38825.0 74011.0 34565.0 25511.0 False True 17589.541287811175 15938.010869001071 14086.146684993293 24710.820505797034 21388.360179069 16368.672862046935 40835.16852781603 77449.82125043898 30671.925714413817 29920.542358729246 0.587875081839199 0.5326778732121209 0.4707851387220491 0.8258814365571723 0.7148386524092869 0.5470713954913125 1.3647870429027322 2.5885166225218232 1.025112624854053 1.0 14.868848706217424 -7.363965580178171 4.395369987466659 1.6640938766225621 0.6180724910998768 0.5002590358403884 0.42594370843524887 0.16403060234614225 5.341816541190757 0.17650195833560137 0.11608283926972995 4.3254811109052906e-08 7.363965580178171 -1.0460213855226854 FHHTIGGSR ddPTM_PC-9_AZD4547_30min_R2 2 FHHTIGGSR 9 0 P61313;E7ERA2 P61313 RPL15 60S ribosomal protein L15;Ribosomal protein L15 0 ; 88.177 0.0086612 6528300.0 8194.0 7857.400000000001 41747.0 87497.0 52959.0 46827.0 26743.0 65242.0 35607.0 55732.0 False True 10799.521554212148 10397.150890168376 41193.407502994785 67325.91846517437 45606.556988881384 43898.90028744841 29123.07519194427 55160.34801201365 37489.11332686878 53780.83964350054 0.2008061165612032 0.19332444340937097 0.7659495049920263 1.2518569607960883 0.8480075300273408 0.8162553909244075 0.5415139552486294 1.025650554689319 0.697071923297861 1.0 15.714804658747932 -5.298799109918419 4.525427131730879 0.8739349536201133 0.18865826581289208 0.6878098744278415 0.18189675287561322 0.10697588880781564 5.232888936240823 0.0491197799750601 0.11472183075683814 5.025750101302797e-06 5.298799109918419 -0.6852766878072212 FHPEPYGLEDDQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FHPEPYGLEDDQR 13 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 0 ; 149.41 3.9581e-08 2423600.0 22272.5 25261.2 31801.0 24334.0 35206.0 28193.0 29141.0 25162.2 26612.0 20150.9 False True 26042.794348073192 27768.964990545242 32559.256445964093 22970.644871892433 28307.637028385634 26714.509449060006 26380.553517430235 24501.71891155464 27001.150155042273 23804.098655563368 1.0940466482223474 1.166562338375086 1.3678004329037896 0.9649869631389658 1.189191720215364 1.1222651122232865 1.1082357664176758 1.0293067284792246 1.1343067656431387 1.0 14.538922381694372 -7.781449541342531 0.3334636755856033 0.9983438383537081 1.1901850373291105 0.18580184163907865 0.09717647558149939 2.2558660282200833 0.8009767119850384 0.14638499516788367 0.1459916929801495 1.6540569507975575e-08 7.781449541342531 0.19184119897540242 FHPEPYGLEDDQR ddPTM_PC-9_Lapatinib_30min_R1 2 FHPEPYGLEDDQR 13 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 0 ; 118.76 0.00020008 11543300.0 64736.0 59961.0 57369.0 49309.0 52517.0 51693.0 39972.0 47449.0 52440.0 42309.0 False True 63812.85276887158 59822.16398849284 52652.34227074406 52935.348350001994 49428.05331239463 49482.210892268566 42041.55457550188 49653.65376109074 46533.6549823191 49622.054276801166 1.285977650439691 1.2055559742608304 1.0610673628511906 1.0667705946778956 0.9960904285960359 0.9971818300033988 0.8472352704502352 1.0006368032269142 0.9377615590589138 1.0 15.598693841374041 -4.879516039492913 0.6429981959105991 0.9471890992056096 1.4887502864766833 0.8548620423951054 0.04565216971505154 1.0503876745581184 0.3580235073049282 0.021788291181877004 0.41226521159293056 1.319726570273033e-05 4.879516039492913 0.5415611872710737 FHPEPYGLEDDQRS(ph)MGYDDLDYGMMSDYGTAR ddPTM_PC-9_AZD4547_30min_R2 1 FHPEPYGLEDDQRSMGYDDLDYGMMSDYGTAR 32 1 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 FHPEPY(0.032)GLEDDQRS(0.676)MGY(0.244)DDLDY(0.036)GMMS(0.008)DY(0.004)GT(0.001)AR 47.273999999999994 0.0030044 12636000.0 14605.0 4839.8 16852.0 48639.0 41719.0 17890.0 14940.0 24380.0 13875.0 22639.0 True False 19249.086197128207 6404.170702552613 16628.531469098798 37426.030015059005 35927.036972358634 16771.335471895523 16269.631057385011 20612.63119666615 14608.404173626082 21846.415500775307 0.8811095896461859 0.29314514787679175 0.7611560564024185 1.7131428271942732 1.6445277702918184 0.7676927810560192 0.744727713194305 0.9435246343243187 0.6686865482855824 1.0 14.415108965294461 -12.161700857725437 1.973691125906275 2.0091667073882507 0.9447370590110875 0.001751917052922658 0.41109983427019325 36488352.85516507 2329090.88051855 164147422.50197956 0.11579556821293324 6.891268038210545e-13 12.161700857725437 -1.0644296483771631 FHPEPYGLEDDQRSMGY(ph)DDLDYGMMSDYGTAR ddPTM_PC-9_AZD4547_30min_R2 1 FHPEPYGLEDDQRSMGYDDLDYGMMSDYGTAR 32 1 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 FHPEPY(0.001)GLEDDQRS(0.237)MGY(0.729)DDLDY(0.031)GMMSDYGTAR 63.925 0.00076891 14213000.0 15835.0 12352.0 37431.0 47141.0 38930.0 35792.0 24231.0 36002.0 22831.0 36335.0 True False 20870.200611538858 16344.542443474911 36934.64048301905 36273.37077118969 33525.241480714365 33553.92058189405 26387.51205833307 30438.7181436577 24037.80004958972 35062.92270951327 0.5952213620194405 0.46614888835380264 1.0533816815275914 1.0345221666688957 0.9561450925943006 0.9569630250130349 0.7525759411714306 0.8681169677677518 0.685561789835272 1.0 15.09765863813341 -5.254151739094295 24.997596929415774 0.9103615438431785 0.5306850884306288 0.6366406362185649 0.11563703063504598 366.51123569596507 1257175.5717301422 0.031534946789257216 0.07985068013209415 5.569911065956034e-06 5.254151739094295 -0.3796764554125497 FHPIQGHR ddPTM_PC-9_AZD4547_30min_R2 1 FHPIQGHR 8 0 Q13151 Q13151 HNRNPA0 Heterogeneous nuclear ribonucleoprotein A0 0 89.55 0.010693000000000001 0.0 9871.3 8858.8 11845.0 16878.0 11355.0 12435.0 13755.0 10770.0 9759.0 14336.0 False True 13010.16806420484 11722.233856724064 11687.927560614493 12987.03786250058 9778.554251567211 11657.43748423817 14979.1683530342 9105.743969979258 10274.84081660663 13834.10100353879 0.9404418878304281 0.8473433766115698 0.8448635410154008 0.9387699178413161 0.7068442140957217 0.8426595614168333 1.08277135964256 0.6582100251870353 0.7427183605192925 1.0 13.755941274319369 -2.6354882087912976 1.43730170810829 0.8440546027626519 50.63115185894327 0.04006162598598706 0.1241332574027018 2735.600195783707 14.396877413043809 0.03527903172718358 446899.4532469304 0.0023147910323436747 2.6354882087912976 49.787097256180616 FHPIQGHR ddPTM_PC-9_Lapatinib_30min_R1 1 FHPIQGHR 8 0 Q13151 Q13151 HNRNPA0 Heterogeneous nuclear ribonucleoprotein A0 0 131.04 0.0032955999999999997 1596800.0 13872.0 11776.0 14042.0 10865.0 11309.0 14253.0 13228.0 10698.0 12762.0 12338.0 False True 13674.182736186753 11748.733395515277 12887.520963687508 11664.048344577504 10643.826854349456 13643.432415365789 13912.881114898915 11195.068134969088 11324.609170182233 14470.6068606484 0.9449626313442696 0.8119032953251581 0.8905998958989093 0.8060510838904001 0.7355480635227849 0.942837611908866 0.961458026527818 0.773641924127808 0.7825939353641455 1.0 13.820837805668518 FHQLDIDDLQSIR ddPTM_PC-9_AZD4547_30min_R2 2 FHQLDIDDLQSIR 13 0 O75828;E9PQ63;A8MTM1;P16152-2;P16152 O75828;P16152 CBR3;CBR1 Carbonyl reductase [NADPH] 3;Carbonyl reductase [NADPH] 1 0 ; 215.34 1.769e-14 14636000.0 56550.0 47341.0 64678.0 88138.0 79092.0 76465.0 49404.0 72709.0 57719.0 64418.0 False True 74531.72368692904 62643.052446287744 63820.327460145534 67819.14581852563 68111.44102729674 71683.63146218525 53800.86029177033 61473.49473660366 60769.90850432605 62162.74542731319 1.1989773484840511 1.0077266056328895 1.026665199894856 1.0909934133753225 1.0956955095707501 1.1531606425910648 0.865483979543336 0.9889121581427662 0.9775937032154447 1.0 15.923762601552852 -7.254280364160851 24.997997005130426 0.9570734724430079 1.0882153122958838 0.5394511573176943 0.06203447421360137 461.7250987825647 1612264.604355588 0.024144741209170786 0.018299621728344588 5.568261668762953e-08 7.254280364160851 0.13114183985287586 FHQLDIDDLQSIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FHQLDIDDLQSIR 13 0 O75828;E9PQ63;A8MTM1;P16152-2;P16152 O75828;P16152 CBR3;CBR1 Carbonyl reductase [NADPH] 3;Carbonyl reductase [NADPH] 1 0 ;; 106.54 0.00092892 9558700.0 37541.0 43966.0 48665.0 43620.0 54953.0 53842.0 51121.0 45200.0 41076.0 40383.0 False True 43895.949831452046 48330.65391882851 49825.358163040226 41176.11281794804 44185.3541334112 51018.43073657605 46278.44879601083 44013.54789335872 41676.65879184269 47704.118228347885 0.9201710766632962 1.0131337862169794 1.0444665998130074 0.8631563551986876 0.9262377290343524 1.0694764442005482 0.9701143321523579 0.9226362320057293 0.8736490755860274 1.0 15.541826196957455 -7.746644738915684 6.998356346703608 0.9234379912797877 0.9746111483676093 0.07083334635633631 0.06437580381550592 0.34813172197811054 78.12575048523975 0.03301483252273262 0.017904322344907207 1.7920712026846395e-08 7.746644738915684 0.051173157087821664 FHQLDIDDLQSIR ddPTM_PC-9_Lapatinib_30min_R1 3 FHQLDIDDLQSIR 13 0 O75828;E9PQ63;A8MTM1;P16152-2;P16152 O75828;P16152 CBR3;CBR1 Carbonyl reductase [NADPH] 3;Carbonyl reductase [NADPH] 1 0 ;; 173.59 0.00016029 9249300.0 52384.0 45326.0 47375.0 41845.0 48967.0 50587.0 44071.0 41599.0 46103.0 41356.0 False True 51636.9945539509 45221.05043182116 43480.01037278847 44922.420890827925 46086.85733282606 48423.51193405665 46352.78073894089 43531.84140461577 40910.394653887466 48504.32949659385 1.0645852667147382 0.9323095670252848 0.8964150380811221 0.9261528065032327 0.9501596622640139 0.9983338072420346 0.9556421296823814 0.897483623759251 0.8434379998338157 1.0 15.565825907560386 -7.75707955846854 23.843525620328748 0.9028455996679146 0.9566986929078365 0.11647076852368432 0.0561924036869286 114.35984912598627 625445.0291343149 0.027510744078151766 0.015152237230437546 1.7495261633177823e-08 7.75707955846854 0.053853093239921934 FHS(ph)PSTTWSPNK ddPTM_PC-9_Lapatinib_30min_R1 2 FHSPSTTWSPNK 12 0 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 FHS(0.91)PS(0.089)T(0.001)TWSPNK;FHS(0.784)PS(0.208)T(0.007)TWSPNK 95.98100000000001 0.0025085 38087000.0 142293.0 285020.0 368030.0 283290.0 410790.0 431690.0 402900.0 458360.0 390400.0 315260.0 True False 140263.8757266595 284360.05370157614 337771.99403688306 304124.09162773663 386628.1398442138 413227.62501854025 423760.1905951599 479657.07892544655 346429.0409057473 369752.27094245603 0.3793455422711617 0.769055597621551 0.913508910103354 0.8225077045573224 1.0456410148847581 1.117579681026084 1.146065146577853 1.2972390344022926 0.9369220100332027 1.0 18.4961994825248 -4.730839916369124 0.6552106141284675 1.1175051193064858 3.6417402488648274e-17 0.7773478996969195 0.1130861705184893 1.624696706228573 0.5038774646603128 0.052720151850266454 1.385500323154833 1.8584893795248893e-05 4.730839916369124 -1.1175051193064858 down FHSPS(ph)TTWSPNKDTPQEK ddPTM_PC-9_AZD4547_30min_R2 1 FHSPSTTWSPNKDTPQEK 18 1 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 FHS(0.013)PS(0.357)T(0.309)T(0.309)WS(0.012)PNKDTPQEK 68.48100000000001 0.005635899999999999 13932000.0 13879.0 12837.0 20528.0 32420.0 30392.0 25146.0 20316.0 28330.0 21201.0 24282.0 True False 18292.233298866304 16986.309208782994 20255.785307243063 24946.069884006927 26172.59540410663 23573.616644845453 22124.084642693037 23952.249458636266 22321.64157730067 23431.894570865592 0.7806553261642887 0.7249225689971814 0.8644535867973905 1.0646202682656318 1.1169645427070471 1.0060482550205767 0.9441867611593541 1.0222071197101434 0.9526178734627215 1.0 14.516185986652346 -5.559975360439067 3.847812607316101 1.0164143706804463 0.7577500394815331 0.8239258097206263 0.04938462672309803 0.08868983411891414 2.807525395086867 0.015009067399937908 0.028958973921202204 2.7543849680707776e-06 5.559975360439067 -0.2586643311989132 FHSPS(ph)TTWSPNKDTPQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FHSPSTTWSPNKDTPQEK 18 1 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 FHS(0.001)PS(0.314)T(0.314)T(0.314)WS(0.057)PNKDTPQEK;FHS(0.015)PS(0.327)T(0.327)T(0.327)WS(0.004)PNKDTPQEK;FHS(0.124)PS(0.61)T(0.139)T(0.124)WS(0.003)PNKDT(0.001)PQEK 72.797 0.0036236999999999997 50389400.0 178179.0 124954.0 220848.0 286704.0 314396.0 260872.0 263101.0 232313.0 256714.0 189385.0 True False 208341.1855043367 137358.60732778313 226113.8538907037 270640.9043869091 252792.3607105697 247191.41308109066 238178.16859371407 226215.0299059699 260467.95659482625 223719.0013291648 0.9312628085524025 0.6139782786071134 1.0107047347221763 1.2097358864422365 1.1299548058442668 1.1049191691920266 1.0646309306703683 1.0111569806854832 1.16426389822647 1.0 17.771328269766215 -5.448778764366095 6.063845240966819 1.0995449824914674 0.7765189833842893 0.6543491863427435 0.09318732293589672 0.12171496509797522 7.7799707729848375 0.023257984068067995 0.04874944512439575 3.5581252824766342e-06 5.448778764366095 -0.3230259991071781 FHSPS(ph)TTWSPNKDTPQEK ddPTM_PC-9_Lapatinib_30min_R1 1 FHSPSTTWSPNKDTPQEK 18 1 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 FHS(0.02)PS(0.313)T(0.313)T(0.313)WS(0.04)PNKDTPQEK 58.98 0.014209999999999999 10771000.0 24216.0 18019.0 25072.0 19932.0 24983.0 26583.0 19377.0 26541.0 26621.0 17685.0 True False 23870.675399329488 17977.27811258407 23010.676940718775 21397.865771202833 23513.54905846782 25446.107057999616 20380.24624761083 27774.191752684113 23622.66264844235 20741.828686218756 1.1508471967657121 0.8667161601102461 1.1093851602393903 1.0316287003864784 1.1336295084767836 1.226801524732796 0.9825674754102965 1.3390425778194661 1.1388900663391204 1.0 14.340255473326275 -6.295850893988932 4.257354843367164 1.151937012231275 1.031336503214584 0.13177141526173053 0.11837053413070361 0.3651263264666779 15.366942962444348 0.03561593446918133 0.04219932328942974 5.059983562347477e-07 6.295850893988932 -0.12060050901669106 FHSQLMR ddPTM_PC-9_Lapatinib_30min_R1 1 FHSQLMR 7 0 P49458 P49458 SRP9 Signal recognition particle 9 kDa protein 0 153.88 0.00040157 2379100.0 13942.0 12217.0 9494.2 8439.3 9740.1 9844.6 9136.0 9193.3 11306.0 9780.1 False True 13743.184523350325 12188.71228711024 8713.62352467183 9059.954274679509 9167.206467773383 9423.569406883467 9609.017377208687 9620.454279791671 10032.599222541947 11470.577253835903 1.1981249259931042 1.062606703863503 0.7596499576128904 0.7898429236985216 0.7991931238428088 0.8215427348028286 0.8377100092321258 0.8387070734887795 0.8746376926398295 1.0 13.485650375985209 -5.07828226115931 3.7113330866088723 0.831015305576871 1.178676887971559 0.7792445342991778 0.06333650063660068 0.09054991973070242 2.3090666510526465 0.015812279719494702 0.054688435431996356 8.350601109244526e-06 5.07828226115931 0.34766158239468803 FHVEEEGK ddPTM_PC-9_AZD4547_30min_R2 1 FHVEEEGK 8 0 P00558;P00558-2;P07205 P00558 PGK1;PGK2 Phosphoglycerate kinase 1;Phosphoglycerate kinase 2 0 150.05 0.00052583 15881000.0 140350.0 176400.0 141060.0 134960.0 140740.0 174690.0 165310.0 185620.0 181540.0 159590.0 False True 184978.3805386477 233417.85030998854 139189.45223303317 103847.0571112144 121200.68034923566 163766.60668448478 180022.2697520958 156936.69412326373 191135.8337787445 154002.80267541544 1.2011364554742425 1.5156727426704857 0.903811163270816 0.6743192676180577 0.7870030820457515 1.0634001709023961 1.1689545035847198 1.0190508964569425 1.2411191904188434 1.0 17.23259708100069 -5.269431162807679 24.941495408075752 0.9744893760654311 1.3584046043587659 0.43030025733377697 0.17296386769869043 514.1624447981629 1604649.0124157872 0.049761255290846976 0.10660607327914673 5.3773565934800194e-06 5.269431162807679 0.3839152282933348 FHVEEEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FHVEEEGK 8 0 P00558;P00558-2;P07205 P00558 PGK1;PGK2 Phosphoglycerate kinase 1;Phosphoglycerate kinase 2 0 ; 137.9 0.0026 23849000.0 158489.0 240131.0 191922.0 178800.0 212337.0 145193.0 190301.0 135000.0 144918.0 126086.0 False True 185318.0573995628 263969.618709508 196498.14834823774 168782.41567742155 170731.08912390858 137578.82348233147 172274.31162007124 131456.3930443233 147037.15159207978 148944.3937037734 1.2442096865232188 1.7722695842751983 1.3192718669159254 1.1331907934252483 1.1462740213201004 0.9236925275344956 1.1566350859952292 0.8825870499413967 0.9871949385655506 1.0 17.184414295721588 -5.762815552116809 1.9186616284625317 1.0134949857389282 1.5168166373298477 0.6439777742448263 0.1457150455591197 0.19082861209645724 1.4328294340761312 0.0428952726782179 0.0860875537857571 1.7265710230029648e-06 5.762815552116809 0.5033216515909196 FHVEEEGK ddPTM_PC-9_Lapatinib_30min_R1 2 FHVEEEGK 8 0 P00558;P00558-2;P07205 P00558 PGK1;PGK2 Phosphoglycerate kinase 1;Phosphoglycerate kinase 2 0 ; 144.12 0.0013838 34655000.0 302030.0 339840.0 323920.0 308490.0 338610.0 301200.0 371040.0 338960.0 267940.0 338080.0 False True 297722.9968144816 339053.12135970703 297288.5479673592 331177.3836924731 318693.6255328739 288318.3781314931 390250.63568733685 354709.3190343168 237761.77566671564 396516.6775367175 0.7508460896626786 0.855079093938768 0.7497504261717471 0.8352167826832606 0.8037332187707611 0.7271279985563653 0.9841972804566325 0.8945634298105171 0.5996261674130942 1.0 18.5970220215603 -7.217570396656791 24.995326224738786 0.8608108365236073 0.7913200388472167 0.11955211232804885 0.10843779746492882 1199.627108783886 683514.9460002241 0.04059316614715957 0.03144323258034161 6.059399731549726e-08 7.217570396656791 -0.06949079767639066 FICEQDHQNFLR ddPTM_PC-9_AZD4547_30min_R2 4 FICEQDHQNFLR 12 0 Q92598-2;Q92598-3;Q92598;A0A0A0MSM0;Q92598-4 Q92598-2 HSPH1 Heat shock protein 105 kDa 0 ;;; 248.21 5.2073e-30 26418100.0 102551.0 98531.0 106258.0 168972.0 133053.0 119268.0 98042.0 131206.0 95324.0 128638.0 False True 135160.08480668918 130379.21887127803 104848.9494922562 130018.11599137612 114580.88761195705 111810.15310575928 106767.54806747951 110931.1275139368 100362.63203219706 124134.42277436014 1.0888203431885324 1.0503067236093657 0.8446404079458342 1.0473977570887876 0.9230387917478087 0.9007183552059307 0.8600962221538784 0.8936371155934478 0.8084996070318609 1.0 16.921543708193482 -1.522883075238831 0.46062046521939615 0.8872827761079582 6.143902216047652 0.43136975888368856 0.0699994275532819 81.82587384330178 0.961895892267832 0.04146922731445786 407.2217185177044 0.029999700898554634 1.522883075238831 5.256619439939694 FICEQDHQNFLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FICEQDHQNFLR 12 0 Q92598-2;Q92598-3;Q92598;A0A0A0MSM0;Q92598-4 Q92598-2 HSPH1 Heat shock protein 105 kDa 0 223.08 2.505e-15 10100000.0 34509.0 29158.0 34241.0 36314.0 40245.0 31929.0 30265.0 27280.0 25881.0 21460.0 False True 40350.69211618172 32052.613541491202 35057.435299715624 34279.444311576495 32359.28115114979 30254.587032207877 27398.080100374948 26563.928905549234 26259.46066295843 25350.52812273346 1.591710118259692 1.2643765599797328 1.3829074932871852 1.352218152837451 1.2764736495620037 1.1934499701833285 1.0807695984765429 1.0478649114109635 1.0358545800633585 1.0 14.629728182482681 -6.738712607834341 0.5693091270922385 0.9841732258376044 1.4595048217696107 0.8438120785409846 0.07062057071063926 0.33847666681614264 0.23810581313374685 0.0578836979599755 0.07002396019415316 1.825103055464701e-07 6.738712607834341 0.47533159593200636 FICEQDHQNFLR ddPTM_PC-9_Lapatinib_30min_R1 4 FICEQDHQNFLR 12 0 Q92598-2;Q92598-3;Q92598;A0A0A0MSM0;Q92598-4 Q92598-2 HSPH1 Heat shock protein 105 kDa 0 ;;; 244.0 1.0184999999999999e-29 26943300.0 94932.0 87319.0 90203.0 79655.0 89989.0 90732.0 76182.0 80275.0 90157.0 71031.0 False True 93578.25227160346 87116.81822036336 82786.85753364951 85513.09442129056 84696.02394518108 86851.60386662236 80126.33119861115 84004.86955829524 80002.56926470152 83308.61370714182 1.123272229694794 1.0457120139654308 0.9937370681100701 1.026461618025457 1.0166538629836823 1.0425284973764581 0.9618012788003234 1.0083575493597936 0.9603156949164684 1.0 16.34617805053177 -1.5228787613851051 0.8397652913315216 0.999246835635786 42.16879903593668 0.7002926744936427 0.024493082115788066 352.88430611176204 1.0265390733314705 0.008573165326368449 27733.853046895 0.029999998887522087 1.5228787613851051 41.16955220030089 FICTTSAIQNR ddPTM_PC-9_Lapatinib_30min_R1 1 FICTTSAIQNR 11 0 P53396;P53396-2;P53396-3;K7ESG8 P53396 ACLY ATP-citrate synthase 0 104.42 0.0093134 0.0 8835.7 7210.7 11362.0 8969.5 9200.2 7989.6 7403.8 9616.9 8237.0 7175.3 False True 8709.701297731062 7194.0040671740835 10427.860218588332 9629.146951374867 8659.062324289142 7647.903432667264 7787.1325369283795 10063.7362822195 7309.262320544671 8415.541044513737 1.0349544077631343 0.8548474814776171 1.2391194058029658 1.1442100870807712 1.0289370913274984 0.9087833321962214 0.925327616577305 1.195851369387623 0.8685433630330551 1.0 13.03884031167123 -6.524420997945537 24.942191277257546 0.9863564675768489 1.0679067670421727 0.10384850661277634 0.1221934453722683 135.9926961834714 2199276.1452792846 0.04140794129643195 0.041709610151547255 2.989365389829994e-07 6.524420997945537 0.08155029946532377 FICVTPTTCSNTIDLPMS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 FICVTPTTCSNTIDLPMSPR 20 0 G8JLH9;P40763-2;P40763 G8JLH9 STAT3 Signal transducer and activator of transcription;Signal transducer and activator of transcription 3 1 FICVTPTTCSNT(0.001)IDLPMS(0.999)PR 106.11 9.2606e-05 8491800.0 14454.0 14209.0 22334.0 34655.0 24752.0 23787.0 20055.0 26866.0 20317.0 20394.0 True False 19050.07133812331 18801.781377860672 22037.836567223632 26665.82516441269 21315.612050620126 22299.595129680223 21839.856148317027 22714.477019263035 21390.915142022433 19680.012267450496 0.967990826389419 0.9553744744843293 1.1198080706317866 1.3549699462594487 1.0831096932736577 1.133108802303053 1.1097480962671338 1.1541901859904504 1.086936067484148 1.0 14.264443499524594 -5.288946122494157 5.730894615550531 1.1421347782699298 0.960722373860756 0.3768574386301462 0.08582561760435542 0.15772161501366505 17.123472201535183 0.022392097632336516 0.05027886151370623 5.141074265300198e-06 5.288946122494157 -0.18141240440917383 FICVTPTTCSNTIDLPMS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FICVTPTTCSNTIDLPMSPR 20 0 G8JLH9;P40763-2;P40763 G8JLH9 STAT3 Signal transducer and activator of transcription;Signal transducer and activator of transcription 3 1 FICVTPTTCSNT(0.08)IDLPMS(0.919)PR;FICVTPTTCSNT(0.001)IDLPMS(0.999)PR 97.057 0.00032117 7018300.0 21114.9 18185.1 24839.8 27758.2 33153.0 32447.0 36235.0 29384.0 33141.0 30380.5 True False 24689.23553171538 19990.396546860942 25432.075037466086 26202.998047298617 26656.90764080183 30745.422200321005 32802.55848131792 28612.701134921506 33625.62442838781 35888.24415809431 0.6879477141025557 0.5570179599425252 0.7086464003486245 0.7301276131501333 0.7427754760966642 0.8566989810056399 0.9140195975266058 0.7972722490651061 0.9369537356093754 1.0 15.131223720190865 -6.343967718441175 0.33158170097928047 0.9922221345340958 0.5200939139202629 0.8231557270462113 0.05362481169129904 1.0201639475899702 0.19289637301438897 0.06320848714283044 0.17976420032500412 4.5293124550117905e-07 6.343967718441175 -0.47212822061383286 FICVTPTTCSNTIDLPMS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 FICVTPTTCSNTIDLPMSPR 20 0 G8JLH9;P40763-2;P40763 G8JLH9 STAT3 Signal transducer and activator of transcription;Signal transducer and activator of transcription 3 1 FICVTPTTCSNTIDLPMS(1)PR 77.83800000000001 0.0010765999999999998 3626100.0 9399.9 7191.5 18355.0 10178.0 14990.0 17763.0 11728.0 13544.0 22971.0 15284.0 True False 9265.855702269462 7174.848523594445 16845.92275234897 10926.524072812677 14108.317671473897 17003.317897575427 12335.21845445527 14173.303684802899 20383.764084646296 17925.819035350138 0.5168999912359361 0.40025220099820685 0.9397574927610512 0.6095411345649152 0.7870389433058518 0.9485378528057481 0.6881257938691631 0.790664217732691 1.1371175868979282 1.0 14.129751417095504 -4.522526474807141 0.27771659119886133 1.0001460807556346 7.973711421327136e-15 0.5243379796448638 0.15124639896878753 8.66975521974455 0.49683075859096504 0.18955400645801798 3.037947382430909 3.0024343853922263e-05 4.522526474807141 -1.0001460807556266 FIDTTSK ddPTM_PC-9_Lapatinib_30min_R1 1 FIDTTSK 7 0 P39023;G5E9G0;Q92901 P39023 RPL3;RPL3L 60S ribosomal protein L3;60S ribosomal protein L3-like 0 130.04 0.020263999999999997 9110700.0 91039.0 78981.0 89026.0 91523.0 83271.0 76044.0 91975.0 78688.0 69446.0 92688.0 False True 89740.76716549229 78798.12434707831 81706.62593029787 98253.90673177782 78373.16349708504 72791.77538722203 96737.01546286864 82344.1317446672 61624.26018120013 108708.99730100304 0.8255137053376562 0.7248537499513047 0.7516086796759001 0.9038249746681387 0.7209445900791315 0.66960212304847 0.8898712881603965 0.7574730131735603 0.5668735956654025 1.0 16.730111824409796 -10.660299702573303 4.644633728457298 1.0000216084762361 0.7602904581765416 0.3708436725656764 0.09495738341037326 2.3036507687393293e-05 4.278379110387106e-06 0.09118666835306233 0.02211383792689185 2.186252390861749e-11 10.660299702573303 -0.2397311502996945 FIEEHATK ddPTM_PC-9_AZD4547_30min_R2 2 FIEEHATK 8 0 A0A499FI48;P13667 A0A499FI48 PDIA4 Protein disulfide-isomerase A4 0 ; 105.52 0.0029381999999999998 3964000.0 70593.0 68784.0 126988.0 186257.0 158128.0 133125.0 99491.0 150507.0 120425.0 134505.0 False True 93040.10557438365 91017.08285556828 125304.0561475149 143318.32629196413 136174.656687963 124800.67270520334 108345.50626039451 127249.60145679362 126790.4196474899 129796.0208901356 0.7168178572526227 0.70123168823957 0.9653921228723732 1.104181201465909 1.0491435388703212 0.9615138572764067 0.8347367316606906 0.9803813752079706 0.9768436565155588 1.0 16.985886630269533 -5.276146753499596 6.241115214851264 0.9844421034403779 0.7075818075960885 0.7419819596444246 0.06490297336105338 0.07811891752914812 13.88442823515105 0.019133477609050945 0.0436342625412276 5.29484494271627e-06 5.276146753499596 -0.2768602958442894 FIEEHATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FIEEHATK 8 0 A0A499FI48;P13667 A0A499FI48 PDIA4 Protein disulfide-isomerase A4 0 ; 116.37 0.0030156999999999996 6426200.0 66436.0 67810.0 83971.0 101802.0 108212.0 101220.0 105081.0 78616.0 97503.0 63160.0 False True 77682.30262918807 74541.72865932244 85973.1871017908 96098.3639865372 87008.63540634153 95911.8450123738 95126.96695944176 76552.41330053733 98928.7969174465 74610.40802571499 1.041172467551904 0.9990794934887787 1.1522948255712466 1.288002123690521 1.166172893416605 1.285502218126419 1.274982532284981 1.026028610836078 1.3259382911208581 1.0 16.187089277586395 -5.382588946318415 4.206756767604195 1.203226460610518 1.0209987092952233 0.2991854513407498 0.10468898799097104 0.24396431160931156 7.106173687313178 0.026307109720000405 0.05842316439639211 4.143917052453261e-06 5.382588946318415 -0.18222775131529478 FIEEHATK ddPTM_PC-9_Lapatinib_30min_R1 1 FIEEHATK 8 0 A0A499FI48;P13667 A0A499FI48 PDIA4 Protein disulfide-isomerase A4 0 113.66 0.0018625 0.0 86989.0 83571.0 92039.0 79277.0 80653.0 92749.0 84676.0 73497.0 94394.0 65373.0 False True 85748.52090817098 83377.49648408686 84471.90870081431 85107.29504031948 75909.14910989885 88782.34147847904 89060.10895715005 76911.93893398979 83762.35370711345 76672.63594595308 1.118371891747866 1.0874478939638919 1.1017217245584068 1.1100087272376031 0.9900422513634145 1.1579403835947697 1.1615631555947674 1.0031211003128337 1.0924673799679712 1.0 16.226424158985935 -8.618288366811651 1.0236730261916658 1.0030320159713102 1.097099222203488 0.21793021637176357 0.05315964829321737 1.0330835812178911 2.3148861346486878 0.0509267101417144 0.016647719454054046 2.408305808821193e-09 8.618288366811651 0.0940672062321779 FIEIAAR ddPTM_PC-9_AZD4547_30min_R2 1 FIEIAAR 7 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PRZ7;A0A1W2PQ74;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7;A0A1W2PQD4;A0A1W2PPE9 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 114.72 0.039346 5016100.0 16525.0 24353.0 30016.0 35994.0 33780.0 27543.0 27373.0 26418.0 29015.0 25864.0 False True 21779.60625864728 32224.631001128942 29617.96822789399 27696.139401756478 29090.230085243522 25820.731855920552 29809.14397147254 22335.70512524719 30548.673664703514 24958.509232388904 0.8726324980333229 1.291128035776701 1.1866881932779247 1.1096872470978725 1.1655435753147003 1.034546238940134 1.194347935364221 0.8949134308174915 1.2239782985539938 1.0 14.60724414438785 FIEIAAR ddPTM_PC-9_Lapatinib_30min_R1 2 FIEIAAR 7 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PRZ7;A0A1W2PQ74;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7;A0A1W2PQD4;A0A1W2PPE9 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 ; 124.37 0.021381 21100600.0 145731.0 128823.0 144058.0 114728.0 140475.0 158065.0 120265.0 132569.0 128861.0 117622.0 False True 143652.8492162076 128524.71825836178 132214.10731996142 123165.47984138857 132212.53668447607 151304.9284175116 126491.73323883566 138728.63970692793 114347.31721351288 137952.80597853666 1.0413187915768656 0.9316571514925057 0.9584010008504785 0.8928088049223967 0.9583896155403052 1.0967876104024468 0.9169203362091514 1.0056239068345734 0.8288872154677562 1.0 17.073815276036655 FIGIY(ph)S(ph)VR ddPTM_PC-9_AZD4547_30min_R2 1 FIGIYSVR 8 0 Q8TAF5 Q8TAF5 FLVCR1-AS1 Putative uncharacterized protein LQK1 2 FIGIY(1)S(1)VR 63.184 0.029720999999999997 0.0 1318.2 1068.9 2172.4 2926.6 3126.0 2434.2 2340.1 2487.8 2350.3 921.33 True False 1737.360179736693 1414.401021521239 2143.5925565790544 2251.917585519267 2692.008858687722 2281.9890891944156 2548.3643666256135 2103.36767395677 2474.532059767454 889.0745171310267 1.9541221194180856 1.590868925234073 2.4110381247865007 2.532878338236515 3.0278776489676273 2.566701716475031 2.866311335577342 2.3657945801260523 2.7832673325882444 1.0 9.796160532328106 -5.365928078306997 4.681130160421286 2.5464476090166377 1.7764273752383768 0.1839824655735003 0.5372844977137328 0.277175638738476 9.652167745863693 0.13124167293163921 0.2871587302461576 4.3059791410726995e-06 5.365928078306997 -0.7700202337782609 FIHQQPQSS(ph)SPVYGSSAK ddPTM_PC-9_AZD4547_30min_R2 1 FIHQQPQSSSPVYGSSAK 18 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 FIHQQPQS(0.35)S(0.567)S(0.083)PVYGSSAK 87.49600000000001 0.00092742 21948000.0 62929.0 48687.0 101530.0 137830.0 125140.0 88831.0 73591.0 112110.0 92666.0 102820.0 True False 82939.11299548653 64424.12062382316 100183.6458614765 106055.42295227262 107766.47107363434 83276.38352733101 80140.45643534293 94785.97553151136 97564.13557861162 99220.30309597217 0.8359086840851773 0.6493038079263683 1.0097091294366691 1.0688883186507614 1.0861332581235494 0.8393078929297446 0.8077021933487343 0.9553082642755925 0.9833081792165198 1.0 16.598347743899453 -5.269104385904906 24.992573423257607 0.9645861338976488 0.7426062423509783 0.48406176516586064 0.09332597971510573 480.01004143891066 1565127.6023520809 0.02685190105860602 0.0576364105793359 5.381404209226267e-06 5.269104385904906 -0.22197989154667053 FIHQQPQSS(ph)SPVYGSSAK ddPTM_PC-9_Lapatinib_30min_R1 1 FIHQQPQSSSPVYGSSAK 18 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 FIHQQPQS(0.105)S(0.458)S(0.436)PVYGSSAK 96.848 0.00045857 51455000.0 141150.0 105010.0 129700.0 110720.0 141330.0 144160.0 118300.0 114830.0 155780.0 118330.0 True False 139137.17511626 104766.85579679505 119036.56665647842 118862.71815109243 133017.2472654708 137994.6128533735 124424.99515365454 120165.42100752488 138234.41596387632 138783.182835186 1.0025506857087607 0.7548959006165211 0.8577160735522404 0.8564634109325018 0.9584536436481457 0.9943179716324205 0.8965423087422435 0.8658500154894783 0.9960458691024447 1.0 17.082473233201647 -6.256630604734423 24.012627535325873 0.9445169870716243 0.8591064341854668 0.251980179273109 0.06952915186808085 333.5684949371329 1665671.755894865 0.02042354281884708 0.025491966239536843 5.538209691355745e-07 6.256630604734423 -0.08541055288615751 FIHQQPQSSS(ph)PVYGSSAK ddPTM_PC-9_AZD4547_30min_R2 3 FIHQQPQSSSPVYGSSAK 18 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 FIHQQPQS(0.006)S(0.187)S(0.807)PVYGSSAK;FIHQQPQSS(0.005)S(0.991)PVY(0.002)GS(0.001)SAK;FIHQQPQSS(0.05)S(0.949)PVYGSSAK 150.13 4.518e-05 685005000.0 351693.0 305758.0 512066.0 720191.0 600661.0 578485.0 465688.0 585217.0 431271.0 487473.0 True False 463524.05833116017 404588.29407642473 505275.6702620193 554162.0917900316 517269.58831357345 542312.24150137 507133.3298428048 494785.1595988262 454067.10460280377 470406.7186452324 0.9853687032066757 0.8600818781705241 1.074125113938018 1.1780488454459452 1.09962202453933 1.1528581969730896 1.0780741637860631 1.0518241767970566 0.9652649220455725 1.0 18.843549140238082 -5.305319636666385 9.840304201268037 1.0843771888991045 0.9228282205649778 0.45232526211459956 0.06637338770855723 0.43198268222243746 95.48605768833588 0.017794638683537208 0.03725350109691147 4.950856782654583e-06 5.305319636666385 -0.16154896833412669 FIHQQPQSSS(ph)PVYGSSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 FIHQQPQSSSPVYGSSAK 18 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 FIHQQPQS(0.004)S(0.02)S(0.97)PVY(0.005)GS(0.001)SAK;FIHQQPQS(0.008)S(0.158)S(0.834)PVYGSSAK;FIHQQPQSS(0.002)S(0.991)PVY(0.001)GS(0.005)SAK;FIHQQPQSS(0.232)S(0.768)PVYGSSAK;FIHQQPQSS(0.16)S(0.84)PVYGSSAK;FIHQQPQS(0.063)S(0.214)S(0.723)PVYGSSAK 226.08 6.2336e-35 929056000.0 771416.0 726344.0 952317.0 963265.0 1121300.0 1047005.0 1109504.0 1031093.0 991992.0 779760.0 True False 902001.4926395001 798450.6320797326 975023.8489623336 909296.384997267 901589.3143193991 992098.2146530377 1004403.7490066538 1004027.9012833363 1006498.0063355148 921124.3154232353 0.9792396938572306 0.86682179452929 1.0585149394458584 0.9871592463384993 0.9787922207928467 1.0770513795384846 1.0904106342531557 1.0900026027670422 1.0926842224038482 1.0 19.813036350776798 -6.056868701246636 0.7498510774472894 1.078260182497827 0.9302794162327845 0.4428962678637246 0.051786009626499506 0.6943324468470656 0.7888521665485815 0.02787141249307881 0.06462094476286867 8.772660018617565e-07 6.056868701246636 -0.14798076626504253 FIHQQPQSSS(ph)PVYGSSAK ddPTM_PC-9_Lapatinib_30min_R1 4 FIHQQPQSSSPVYGSSAK 18 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 FIHQQPQS(0.002)S(0.243)S(0.755)PVYGSSAK;FIHQQPQS(0.029)S(0.224)S(0.747)PVYGSSAK;FIHQQPQS(0.001)S(0.175)S(0.824)PVYGSSAK;FIHQQPQSS(0.039)S(0.961)PVYGSSAK 165.24 1.4529999999999998e-07 882384000.0 535530.0 410411.0 541090.0 436637.0 517574.0 521014.0 475137.0 466216.0 584807.0 363260.0 True False 527893.2439958251 409460.71854507626 496603.6688678006 468748.7415583326 487131.3149096358 498731.4457629543 499737.2689968039 487878.09736518405 518939.8773692803 426049.0069864764 1.2390434793633527 0.961064834867866 1.1656022211631718 1.1002225891192172 1.1433692061746743 1.170596428074259 1.172957243889707 1.1451220149908017 1.218028604361358 1.0 18.70065986279846 -6.366548438405787 4.558769528212513 1.1527914027666026 1.1089378547001516 0.008722614630306214 0.08395698591146794 0.7381596481289986 25.11889158007731 0.024871298504964303 0.028382003707008687 4.299832733946137e-07 6.366548438405787 -0.04385354806645103 FIHQQPQSSSPVY(ph)GSSAK ddPTM_PC-9_AZD4547_30min_R2 2 FIHQQPQSSSPVYGSSAK 18 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 FIHQQPQSSSPVY(0.945)GS(0.031)S(0.024)AK;FIHQQPQSSSPVY(0.703)GS(0.283)S(0.014)AK 107.62 0.00050673 16713600.0 53641.0 43930.0 63376.0 93366.0 80040.0 88936.0 40817.0 72785.0 49056.0 59459.0 True False 70697.72219788798 58129.51340202826 62535.59283085719 71841.91119032055 68927.82759096778 83374.81786073247 44449.63392699358 61537.750682909944 51649.00001019109 57377.35850791106 1.2321536584529302 1.0131089146255048 1.0899001706785598 1.252095130528101 1.2013070901732807 1.4530961345882965 0.7746894434128571 1.072509301285197 0.9001634329867214 1.0 15.808193931565809 -7.274488016417493 24.987906876915762 0.9428830007208568 1.1946088554174812 0.512325918260876 0.12870912759955846 729.4309091949123 1396841.838645149 0.054892114348971406 0.0372639989409531 5.315106653942016e-08 7.274488016417493 0.25172585469662434 FIHQQPQSSSPVYGSS(ph)AK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FIHQQPQSSSPVYGSSAK 18 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 FIHQQPQSSSPVY(0.204)GS(0.3)S(0.495)AK 91.51799999999999 0.0034615 0.0 15277.0 12581.0 12090.0 14556.0 12163.0 13924.0 15623.0 8250.7 12240.0 10748.0 True False 17863.094365496207 13829.958535067595 12378.271451580324 13740.474511188713 9779.747462826064 13193.800928198907 14143.076339275003 8034.127867339265 12418.986844195015 12696.52731887881 1.406927572938396 1.0892709626594868 0.9749336287549065 1.0822230493496934 0.77026947740933 1.0391661118690847 1.1139326513514667 0.6327815209276243 0.9781404420505508 1.0 13.632146332851963 -1.5228797552017117 0.7865182001920161 0.9252019576194204 110.32589859707367 0.5121575995047756 0.13665473288736593 370.9782719181848 1.3699384230866725 0.049102519812453276 72214.20220393772 0.02999993023718408 1.5228797552017117 109.40069663945425 FIIPNVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FIIPNVVK 8 0 P00338-3;P00338;P00338-2;P00338-5;F5GYU2;F5GXY2 P00338-3 LDHA L-lactate dehydrogenase A chain 0 94.40700000000001 0.031067 7553700.0 56935.0 56207.0 65602.0 72600.0 75402.0 62151.0 70446.0 58405.0 65808.0 56265.0 False True 66572.9709824918 61786.859500877836 67166.20047697055 68532.45737237576 60627.519377786 58891.69214941751 63772.84489512685 56871.9306352127 66770.31750349545 66465.3991065052 1.0016184643052277 0.9296093957379178 1.0105438525892605 1.0310997645941806 0.9121666339599572 0.886050380214351 0.9594893847389112 0.8556622152238976 1.0045876260594124 1.0 16.02031587010879 -6.276777372964843 24.795505056483066 0.927753532964097 0.9899119790409008 0.22418426166702043 0.050204591504077634 975.884754433347 1577618.098867181 0.014993249307446712 0.01706298907838822 5.287162116041991e-07 6.276777372964843 0.062158446076803764 FIIPNVVK ddPTM_PC-9_Lapatinib_30min_R1 2 FIIPNVVK 8 0 P00338-3;P00338;P00338-2;P00338-5;F5GYU2;F5GXY2 P00338-3 LDHA L-lactate dehydrogenase A chain 0 ; 119.89 0.015849000000000002 76762000.0 408850.0 399960.0 433730.0 435240.0 414470.0 399730.0 422020.0 377850.0 400880.0 364510.0 False True 403019.72402609314 399033.9171934694 398070.3936462171 467249.00151807826 390091.68947937206 382634.4797161417 443870.13064028136 395406.2904092419 355728.67294645426 427515.06782095466 0.9427029696994907 0.9333797735535878 0.9311259967401451 1.0929415982918393 0.9124630190642644 0.8950198683438939 1.0382561084985578 0.9248943959440511 0.8320845268907227 1.0 18.70561574329495 -7.989909592938257 24.96287176015785 0.9035246414241965 0.9630624570746268 0.07807926214370298 0.06814650853047673 409.78199663867866 1013767.4077471249 0.03672949789695695 0.017613142129960443 1.0235060333081273e-08 7.989909592938257 0.05953781565043026 FIIPQIVK ddPTM_PC-9_Lapatinib_30min_R1 2 FIIPQIVK 8 0 A0A5F9ZHM4;P07195;A0A3B3IS95;A8MW50;C9J7H8 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain;L-lactate dehydrogenase 0 ; 135.87 0.01653 25081000.0 171645.0 189045.0 194774.0 190227.0 194841.0 172283.0 194106.0 164448.0 172938.0 185411.0 False True 169197.3108241617 188607.27791739037 178760.4335693825 204216.9281586699 183380.8354521444 164914.85770128854 204155.85891204793 172088.85442693945 153459.90132212616 217459.04430537194 0.7780651817202067 0.8673232172056003 0.8220418430532326 0.9391052407638356 0.8432890709968706 0.7583720338148042 0.9388244097373908 0.7913621389105328 0.7056956486326984 1.0 17.730384187392218 -6.525804375087475 24.996684638771878 0.8285894706667473 0.8557103664366763 0.0 0.08786607596997513 501.98163616198855 4288896.680653477 0.02815457490721048 0.02830877268329045 2.9798583835414815e-07 6.525804375087475 0.027120895769929043 FILPEGASQGMT(ph)PFR ddPTM_PC-9_Lapatinib_30min_R1 1 FILPEGASQGMTPFR 15 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y6T5;H0Y4F5;H0Y314;H0Y7I1 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 FILPEGAS(0.002)QGMT(0.998)PFR 130.47 2.9933000000000003e-05 2393400.0 14674.0 14509.0 16362.0 16898.0 12270.0 14608.0 12355.0 10582.0 13550.0 12023.0 True False 14464.746069117964 14475.405301930305 15016.779519146488 18140.73529007553 11548.30272374815 13983.249892911204 12994.68144652071 11073.67835149028 12023.856312174365 14101.159530359511 1.0257841589534291 1.026540070748441 1.0649322480761718 1.2864711764319021 0.818961213713304 0.9916383019996016 0.9215328298742684 0.7853026786661674 0.8526856451972793 1.0 13.783526179047195 -6.285632636418328 24.99079366668305 0.8904417857842343 1.0930468440690189 0.5354773516786634 0.09378191871440929 636.190437990914 657160.5424769097 0.02988417931025201 0.03390129094369611 5.180448535070251e-07 6.285632636418328 0.2026050582847846 FIMPICDFK ddPTM_PC-9_Lapatinib_30min_R1 1 FIMPICDFK 9 0 Q8WZ42-6 Q8WZ42-6 TTN Titin 0 101.64 0.015815 1965600.0 6016.0 6988.5 9028.1 5201.1 8924.7 7732.4 6508.4 5786.3 7944.0 9673.9 False True 5930.210736800718 6972.31855762216 8285.8444674738 5583.606244360976 8399.7666926353 7401.703277104777 6845.373106154219 6055.152621926687 7049.26306597145 11346.020725338512 0.5226687735160812 0.6145166421255712 0.7302863856902209 0.49212022254563503 0.7403271063903939 0.6523611631146518 0.603328098182192 0.5336807298795084 0.6212982715806852 1.0 13.46989878398872 -8.608101621355596 20.296533094717983 1.0000000001996083 0.6142433226375575 0.6902227361406197 0.07792661969787308 15058.125135054765 3586209.9148584297 0.07395632427867779 0.01909544071633799 2.4654623717105043e-09 8.608101621355596 -0.3857566775620508 FIPHENGVHTIDVK ddPTM_PC-9_AZD4547_30min_R2 1 FIPHENGVHTIDVK 14 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7 O75369-2 FLNB Filamin-B 0 114.87 7.0362e-05 7707300.0 45508.0 37004.0 52348.0 74336.0 61591.0 58538.0 43379.0 59389.0 47885.0 48882.0 False True 59978.59737479702 48964.8193473402 51653.83131642445 57198.98367975135 53040.15278804721 54877.60960613868 47239.64696374196 50211.79467345389 50416.103340835005 47170.65605852284 1.2715234933426376 1.0380355805649895 1.0950416134204175 1.2125967382939669 1.1244311022989018 1.1633844892480212 1.0014625809981001 1.0644709840617443 1.0688022502440004 1.0 15.52560204583556 -7.255126950071568 24.985152436943252 1.0390565347502319 1.144779279232114 0.45054361268912757 0.06305630950848472 521.8343027187813 2065471.4291027414 0.024166792595703653 0.01826081342607095 5.557417827868227e-08 7.255126950071568 0.10572274448188224 FIPHENGVHTIDVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FIPHENGVHTIDVK 14 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7 O75369-2 FLNB Filamin-B 0 64.53399999999999 0.017253 4995500.0 19466.0 22662.0 20827.0 19050.0 25818.0 23908.0 28686.0 23536.0 22868.0 19387.0 False True 22761.209328974863 24911.733592059594 21323.59466683734 17982.6902609333 20759.14823606375 22654.222392371383 25968.654411344996 22918.204938453313 23202.40123799441 22901.70963259244 0.9938650735743491 1.08776741962559 0.9310918271573396 0.7852116959574641 0.9064453514212967 0.9891935037081753 1.13391772177514 1.000720265260782 1.0131296575769193 1.0 14.483167680334471 -7.001097245845345 21.886186189338996 1.0405095885066211 0.9406426190822749 0.2465668554731345 0.07911809918862761 13.078302579613815 260894.77020145892 0.03154079578544384 0.027357506757857825 9.974766869929836e-08 7.001097245845345 -0.09986696942434625 FIPHENGVHTIDVK ddPTM_PC-9_Lapatinib_30min_R1 2 FIPHENGVHTIDVK 14 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7 O75369-2 FLNB Filamin-B 0 ; 102.33 0.00062583 10888500.0 160657.0 142084.0 150423.0 147705.0 162136.0 153162.0 143782.0 135944.0 170045.0 147031.0 False True 158366.00171911466 141755.01322761519 138055.80158957138 158567.71842943563 152599.47925164073 146611.6182980603 151226.328429271 142260.4545279714 150892.74144676662 172445.1124435074 0.9183559886105499 0.8220297532297635 0.8005782224462762 0.919525733043794 0.8849162327035042 0.850192946733065 0.8769534043988193 0.8249607803443869 0.875018951297902 1.0 17.39577771397238 -8.568190025859376 20.855930118845613 1.0000000005312486 0.8608348499700254 0.544231823785702 0.03758978266531296 2446.029599463841 1125860.4234395414 0.03650054761592831 0.009424400877397923 2.7027755040033998e-09 8.568190025859376 -0.13916515056122325 FIQELSGS(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FIQELSGSSPK 11 0 Q01664;I3L254 Q01664 TFAP4 Transcription factor AP-4 1 FIQELSGS(0.958)S(0.042)PK;FIQELSGS(0.605)S(0.395)PK 141.34 0.00013014 150768000.0 678740.0 702630.0 481590.0 708460.0 735820.0 621120.0 751450.0 750210.0 584960.0 575680.0 True False 793637.2762739344 772382.462880099 493072.9320402462 668767.2830583104 591641.3531280672 588547.373780731 680267.2159731284 730517.7824131988 593513.9333644053 680046.226919629 1.1670343056954129 1.1357793519107087 0.7250579630059764 0.9834144453496811 0.8700016700452778 0.8654520097062287 1.0003249618110528 1.074217830341017 0.8727552773181543 1.0 19.375273292977646 -5.085779522698802 11.051180518976821 0.9274220342352265 1.1592566882927333 0.49037066329802415 0.09295455210584293 0.4736689094921341 59.16279613663733 0.02365187026252509 0.06272882554212629 8.207681160812177e-06 5.085779522698802 0.2318346540575068 FIQELSGS(ph)SPKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FIQELSGSSPKR 12 1 Q01664;I3L254 Q01664 TFAP4 Transcription factor AP-4 1 FIQELS(0.026)GS(0.487)S(0.487)PKR 79.804 0.020557 0.0 15574.0 17025.0 16726.0 19204.0 18687.0 17430.0 19013.0 16649.0 17896.0 15886.0 True False 18210.370599478818 18715.129485694753 17124.811273708227 18128.06214020804 15025.41649575192 16515.940116238635 17211.9509978004 16211.981391073654 18157.69514409426 18766.006046493185 0.9703913850588256 0.9972888977722599 0.912544269211101 0.966005344733204 0.8006720480919662 0.8800988380436432 0.9171877572221505 0.8639015329584846 0.9675844236172673 1.0 14.195834014798619 -5.50433786071568 1.7434908828261493 0.9002186132864477 0.9847094874993438 0.1720657322430562 0.055915195179786874 0.5605073746712411 3.2631397046356088 0.016352784524480312 0.048144440038205324 3.13084912304146e-06 5.50433786071568 0.08449087421289614 FIQELSGSS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 FIQELSGSSPK 11 0 Q01664;I3L254 Q01664 TFAP4 Transcription factor AP-4 1 FIQELSGS(0.089)S(0.911)PK;FIQELSGS(0.072)S(0.928)PK;FIQELS(0.011)GS(0.07)S(0.919)PK;FIQELSGS(0.041)S(0.959)PK 220.37 3.9934e-09 369576000.0 933080.0 823590.0 755950.0 906300.0 911430.0 803620.0 915060.0 835160.0 810590.0 837560.0 True False 1229780.0307303257 1089799.3613197452 745925.609071044 697366.5371954185 784893.6769269826 753369.5143613591 996498.5672938895 706105.212067583 853436.1325477168 808237.279333424 1.521558163890386 1.348365621316717 0.9229042363478084 0.8628240184250796 0.9711178845577457 0.93211428577346 1.232928241216156 0.8736360350142817 1.0559227523525883 1.0 19.62441937071084 -5.122558227596546 3.580138826090507 0.9797401990321905 1.4927259695170352 0.7652906464703109 0.1021869820421111 0.1086315490203624 2.455965184795408 0.027018554522238097 0.08985517753475904 7.541222808817535e-06 5.122558227596546 0.5129857704848447 FIQELSGSS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FIQELSGSSPK 11 0 Q01664;I3L254 Q01664 TFAP4 Transcription factor AP-4 1 FIQELS(0.004)GS(0.043)S(0.953)PK 104.81 0.002637 69917000.0 588120.0 578320.0 450690.0 592640.0 589010.0 493200.0 635250.0 634710.0 506380.0 410030.0 True False 687677.1001005191 635731.7876162695 461436.15885134204 559436.302164804 473597.71874366427 467335.72377102135 575074.5211882757 618049.535030833 513784.8495231583 484365.193204305 1.4197492093748718 1.3125051026284587 0.9526616803299252 1.1549886532181803 0.9777699252305707 0.9648416738605314 1.1872746622933112 1.275999067856513 1.0607385847117303 1.0 18.885735670196226 -5.086510605967587 4.97079482243922 1.082237634656891 1.3976128493563005 0.5788094382663505 0.10180619448261197 0.14979653435495976 6.124991424523898 0.027671250031721675 0.08124216831476024 8.19387612553992e-06 5.086510605967587 0.31537521469940955 FIQELSGSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 FIQELSGSSPK 11 0 Q01664;I3L254 Q01664 TFAP4 Transcription factor AP-4 1 FIQELSGS(0.084)S(0.916)PK;FIQELSGS(0.029)S(0.971)PK;FIQELS(0.002)GS(0.132)S(0.866)PK;FIQELSGS(0.099)S(0.901)PK 193.11 0.00016689 330775000.0 1181080.0 936760.0 803190.0 948500.0 952920.0 772770.0 780540.0 801710.0 786920.0 720430.0 True False 1164237.5826164547 934590.9897743647 737154.81860306 1018255.8541032467 896871.1191128027 739720.4285148538 820952.5419884489 838960.3733862463 698288.7829650365 844955.3655873657 1.3778687372523422 1.1060832652677333 0.8724186491089162 1.2051001692798438 1.0614420070453638 0.8754550342438995 0.9715927910792882 0.9929049599005125 0.8264209109786825 1.0 19.688515608084273 -1.7745286316934237 0.9778848245504872 0.9728675176509431 199.9999999759585 0.5776363387368142 0.10363462159809032 626.8030062805965 1.667753721141013 0.03428258102928652 278338.669337942 0.01680627123502458 1.7745286316934237 199.02713245830756 FIQELSGSS(ph)PKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FIQELSGSSPKR 12 1 Q01664;I3L254 Q01664 TFAP4 Transcription factor AP-4 1 FIQELSGS(0.01)S(0.99)PKR;FIQELSGS(0.032)S(0.968)PKR 163.33 0.00044606 21991000.0 138470.0 123030.0 114391.0 149983.0 161187.0 135286.0 137115.0 151384.0 115576.0 117028.0 True False 161910.23609283648 135243.60532305573 117118.51527028347 141579.9387614465 129603.56444056133 128191.36400260817 124126.47457336572 147410.3304046065 117266.08035168964 138244.2500068616 1.171189659496147 0.9782946149032821 0.8471854363886413 1.0241289511456668 0.9374969623266689 0.9272817060835842 0.8978780279628616 1.0663035200183006 0.848252859311467 1.0 17.07685995012934 -4.778588063817176 4.291652720564992 0.9445012386389778 1.1886261033333703 0.5021242863178275 0.06754603037017676 0.15801124685522913 5.969267099463676 0.015779213254536042 0.11740483159075456 1.6649911759115164e-05 4.778588063817176 0.24412486469439243 FIQELSGSS(ph)PKR ddPTM_PC-9_Lapatinib_30min_R1 1 FIQELSGSSPKR 12 1 Q01664;I3L254 Q01664 TFAP4 Transcription factor AP-4 1 FIQELS(0.006)GS(0.225)S(0.769)PKR 71.781 0.012189 35884000.0 45095.0 34164.0 36467.0 39119.0 36654.0 41578.0 33732.0 27565.0 36289.0 26289.0 True False 44451.93703058984 34084.89535702992 33468.82402669078 41995.94175715851 34498.08378453667 39799.80586305188 35478.47790805638 28845.770530979895 32201.750679888966 30833.0186221094 1.4416991594431412 1.1054673489733728 1.0854864532365742 1.3620444456594503 1.118868191510745 1.290817689660547 1.150665082225062 0.9355480527065712 1.0443917630821293 1.0 14.912188519009485 -7.604904128302759 4.7889203967202505 0.9945372699448051 1.2221333967216856 0.4847484551757164 0.11039258190804788 0.1847374639109074 7.593513886693705 0.052516430207461294 0.02948533193854927 2.483681324242793e-08 7.604904128302759 0.22759612677688057 FIQENVFVAANHNGS(ph)PLSIK ddPTM_PC-9_AZD4547_30min_R2 2 FIQENVFVAANHNGSPLSIK 20 0 E9PFD2;P11172-4;P11172-2;P11172-3;P11172 E9PFD2 UMPS Uridine 5-monophosphate synthase;Orotate phosphoribosyltransferase;Orotidine 5-phosphate decarboxylase 1 FIQENVFVAANHNGS(0.994)PLS(0.006)IK;FIQENVFVAANHNGS(0.974)PLS(0.026)IK 123.74 4.0333e-06 70028000.0 310250.0 305590.0 443410.0 528370.0 470700.0 461080.0 371540.0 491440.0 339770.0 440650.0 True False 408903.04639911215 404365.9913618439 437530.0936810529 406562.4597351248 405351.4298734209 432248.59471110074 404606.3402316479 415499.240167744 357729.5485457971 425222.9776234204 0.9616202978599118 0.9509504722013221 1.0289427352360336 0.9561159230091713 0.9532679351876467 1.016522195312555 0.9515157024039498 0.9771326151986833 0.8412752070576115 1.0 18.697860031813107 FIQENVFVAANHNGS(ph)PLSIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FIQENVFVAANHNGSPLSIK 20 0 E9PFD2;P11172-4;P11172-2;P11172-3;P11172 E9PFD2 UMPS Uridine 5-monophosphate synthase;Orotate phosphoribosyltransferase;Orotidine 5-phosphate decarboxylase 1 FIQENVFVAANHNGS(0.991)PLS(0.009)IK;FIQENVFVAANHNGS(0.993)PLS(0.007)IK 109.28 4.9307e-05 43982000.0 276551.0 255771.0 275328.0 285611.0 326077.0 288627.0 305264.0 270910.0 277816.0 228118.0 True False 323365.6221687732 281162.25454834884 281892.8637072548 269609.14163335506 262184.55261332996 273490.8920212051 276347.18400002806 263798.8995528722 281878.53342376545 269473.9876189054 1.1999882624147096 1.0433743792219872 1.0460856210949474 1.0005015475357897 0.9729493927410751 1.0149064643967807 1.0255059734776437 0.9789401265918883 1.0460324423684366 1.0 18.0397864904779 FIQENVFVAANHNGS(ph)PLSIK ddPTM_PC-9_Lapatinib_30min_R1 3 FIQENVFVAANHNGSPLSIK 20 0 E9PFD2;P11172-4;P11172-2;P11172-3;P11172 E9PFD2 UMPS Uridine 5-monophosphate synthase;Orotate phosphoribosyltransferase;Orotidine 5-phosphate decarboxylase 1 FIQENVFVAANHNGS(0.939)PLS(0.061)IK;FIQENVFVAANHNGS(0.986)PLS(0.014)IK;FIQENVFVAANHNGS(0.938)PLS(0.062)IK 92.39 0.000359 25996000.0 155963.0 143000.0 154458.0 143216.0 158287.0 139438.0 126865.0 120650.0 154921.0 101986.0 True False 153738.93901988864 142668.89228589393 141759.05946512177 153748.582394571 148976.86986421564 133474.5617858539 133433.44894478773 126255.83945447959 137472.16558954728 119614.1442121971 1.2852906320773712 1.192742657864921 1.185136259585148 1.2853712527660521 1.245478708604299 1.1158760752329442 1.1155323630295342 1.0555260022635786 1.1492969037647405 1.0 16.868028470814536 -6.838547958780153 4.0227081445258985 1.0884741747835245 1.2362046986732378 0.7163580749516847 0.04789919892987521 0.12856760035170514 4.011178924733443 0.017125752161312464 0.015270690808984116 1.450280612174327e-07 6.838547958780153 0.1477305238897133 FIQTTAS(ph)T(ph)RPS(ph)VS(ph)APT(ph)VR ddPTM_PC-9_Lapatinib_30min_R1 1 FIQTTASTRPSVSAPTVR 18 1 A3KN83-3;A3KN83-2;A3KN83;A3KN83-4 A3KN83-3 SBNO1 Protein strawberry notch homolog 1 5 FIQT(0.002)T(0.02)AS(0.992)T(0.992)RPS(0.997)VS(0.998)APT(1)VR 50.786 0.042821 0.0 3097.5 4409.1 4504.0 4768.3 4686.4 5128.9 5461.5 4386.5 4759.8 4762.8 True False 3053.329081988069 4398.890999844299 4133.69850594278 5118.976688582504 4410.755165816899 4909.5489030498575 5744.269746675266 4590.312803705545 4223.701201083952 5586.043633967916 0.5465995760257261 0.7874788111384029 0.7400046932691973 0.9163868068367302 0.789602705391655 0.8788955519780774 1.0283252554178417 0.8217466787750318 0.756116757735339 1.0 12.44761112757162 -4.176446112436596 0.7860962362374271 0.8827473021103757 1.2690719012975199e-12 0.5647301855214608 0.08736312169699655 4.6675219361434115 1.1247053112916945 0.03258359437850637 4.508416837537045 6.661221690759717e-05 4.176446112436596 -0.8827473021091066 FISGT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 FISGTPR 7 0 Q9Y4B6-3;Q9Y4B6-2;Q9Y4B6 Q9Y4B6-3 VPRBP Protein VPRBP 1 FIS(0.001)GT(0.999)PR 87.696 0.043445 11661000.0 45661.0 42479.0 58890.0 81478.0 76640.0 64548.0 56889.0 75857.0 61842.0 75899.0 True False 60180.24819219934 56209.50602787982 58109.08012195753 62694.50592255132 65999.85890269585 60511.80335605999 61952.01079140405 64135.043670447274 65110.841867054776 73241.79911185763 0.8216653457718835 0.7674511919352848 0.7933868477645006 0.8559935266855189 0.901122852019219 0.8261922029474464 0.8458559394040636 0.8756617730334262 0.888984741726716 1.0 16.160379609486938 -14.522878743387887 0.07933776404425671 1.5463491388619877 0.6756254144750303 0.7814773389870038 0.028873847626329108 125.44974591350129 0.7029024172519514 11.915237818950933 1.1271001015605768 3.000000013072587e-15 14.522878743387887 -0.8707237243869573 FKAEAPLPS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 FKAEAPLPSPK 11 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 FKAEAPLPS(1)PK;FKAEAPLPS(1)PK 92.265 0.035285000000000004 1169880000.0 995825.0 1061122.0 871988.0 1133903.0 1122490.0 1217205.0 1200059.0 941002.0 1123325.0 1095139.0 True False 1312476.6355532468 1404108.935128318 860424.8693731629 872499.1819767158 966651.6390877742 1141092.9789306077 1306861.9261776737 795591.7629747841 1182701.66618656 1056798.5169443681 1.2419364850625902 1.328643930337984 0.8141806177595698 0.8256059863704803 0.9146981412149924 1.0797639858825399 1.2366235429212562 0.7528320206912872 1.1191363795685754 1.0 20.01126891642039 -5.24916618186897 24.916971096743517 0.9656444885709508 1.2852902541742386 0.43970670323511996 0.14331394025709895 685.3003350343721 1391286.1902180589 0.037606473359985494 0.09791229647146801 5.634220223223354e-06 5.24916618186897 0.31964576560328783 FKAEAPLPS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 FKAEAPLPSPK 11 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 FKAEAPLPS(1)PK;FKAEAPLPS(1)PK;FKAEAPLPS(1)PK;FKAEAPLPS(1)PK 108.66 0.0099567 1140204900.0 130605.0 129009.0 148379.0 205835.0 370576.0 454282.0 584493.0 553239.0 449813.0 465734.0 True False 152713.8469336668 141816.16092922117 151916.918090491 194302.73227607415 297964.2930020742 430458.6522022447 529125.5916771333 538717.0624551733 456390.66416240943 550167.8874516833 0.2775768095826538 0.25776888139745474 0.27612829021001817 0.3531698899695198 0.5415879403325624 0.7824132633332735 0.9617529553169387 0.9791866714548737 0.8295479881175188 1.0 19.06951240840891 -6.628595043188773 1.4189645746741764 0.9482566497601735 0.2675271506945662 0.9769602483024651 0.04564289421474544 0.05433215650023282 0.2273838912189898 0.019909842006266738 0.02019524425306123 2.3518247519091077e-07 6.628595043188773 -0.6807294990656074 down FKAEAPLPS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 FKAEAPLPSPK 11 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 FKAEAPLPS(1)PK 53.967 0.043095 505100000.0 413150.0 363340.0 299980.0 327930.0 604450.0 719670.0 949970.0 865570.0 869920.0 696030.0 True False 407258.4052375698 362498.7085535426 275316.80235628615 352047.0661424115 568897.4393944232 688891.391732708 999154.7983610906 905787.5421186369 771940.4489362902 816337.8580983229 0.4988846238079504 0.44405475619860557 0.3372584030313659 0.4312516719027498 0.6968896930980052 0.8438802450464514 1.2239476442862074 1.1095743424526323 0.9456139284469087 1.0 19.638806839039724 -6.685777966146115 1.7632980266734442 1.0752190646786952 0.42126095622607984 0.9121357689840361 0.08867033383307642 0.09489603929716653 0.6087478413596664 0.03722903588906123 0.0359810158665054 2.061683683457059e-07 6.685777966146115 -0.6539581084526154 down FKDPNAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FKDPNAPK 8 1 Q5T7C4;P09429;B2RPK0;P23497 Q5T7C4;P23497 HMGB1;HMGB1P1;SP100 High mobility group protein B1;Putative high mobility group protein B1-like 1;Nuclear autoantigen Sp-100 0 71.37899999999999 0.046106 9529400.0 49570.0 51640.0 47210.0 58263.0 63057.0 52684.0 57655.0 43439.0 43624.0 39340.0 False True 57961.22194787239 56766.47792312934 48335.66544492201 54998.71300119457 50701.43350846201 49921.158295118585 52193.50101394738 42298.77227742497 44261.918471500234 46472.030584731336 1.2472280900700712 1.2215192064747071 1.040102290275282 1.1834798761572671 1.0910096432308742 1.074219431924726 1.123116428467317 0.91019849456121 0.9524421015087461 1.0 15.50407506400469 -6.08321370193128 0.36163749764571634 0.948272490464443 1.2931268154901214 0.6361234991205289 0.06429971411440959 1.7190834973588731 0.35148902260764536 0.07075294139633079 0.2389394681878797 8.256315836472944e-07 6.08321370193128 0.3448543250256785 FKIDSNIS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 FKIDSNISPK 10 1 Q9H501 Q9H501 ESF1 ESF1 homolog 1 FKIDS(0.007)NIS(0.993)PK 55.98 0.041335000000000004 183110000.0 474190.0 397240.0 365540.0 401100.0 407060.0 428220.0 462300.0 356950.0 318580.0 417760.0 True False 624972.5562352769 525640.061548411 360692.7007604073 308632.5919332255 350546.74536705925 401443.33570570836 503443.8044062321 301791.5793949944 335419.4884060398 403134.3495562472 1.5502835640853219 1.303883090406493 0.8947208322918705 0.7655824721285965 0.8695531545573477 0.9958053342455184 1.2488238845446964 0.7486129121152626 0.8320290463346897 1.0 18.620901189461968 -5.079626528148573 2.8907472150114115 0.9171075091084396 1.5332509865277348 0.6999415407227142 0.13718137913660608 0.16135949808739247 2.4821216780671143 0.039071863317402325 0.1647529999261513 8.324793545937976e-06 5.079626528148573 0.6161434774192952 FKIDSNIS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FKIDSNISPK 10 1 Q9H501 Q9H501 ESF1 ESF1 homolog 1 FKIDS(0.006)NIS(0.994)PK 54.871 0.043611000000000004 167490000.0 162210.0 119230.0 96399.0 146430.0 131340.0 127640.0 166620.0 152790.0 110840.0 110590.0 True False 189668.94920646303 131066.36643638088 98697.51775524337 138226.001832465 105604.86983207909 120946.333702622 150836.5473756641 148779.4243943864 112460.82531132165 130639.0915700415 1.451854471176975 1.003270650930011 0.7554975816892234 1.0580753446096631 0.808371128143214 0.9258050729614666 1.1546049927543611 1.1388583815635234 0.8608512502632211 1.0 16.995227138361237 -4.766461359800656 5.306655435166467 0.9655400337847589 1.4763108639988787 0.5752286529921569 0.12530457777354087 0.1154221064434625 9.583820354698284 0.03245985024472484 0.21669883469225196 1.7121375028183632e-05 4.766461359800656 0.5107708302141197 FKIDSNIS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 FKIDSNISPK 10 1 Q9H501 Q9H501 ESF1 ESF1 homolog 1 FKIDS(0.043)NIS(0.957)PK 57.106 0.039022 139970000.0 40282.0 80505.0 28887.0 39751.0 30299.0 26766.0 22175.0 28829.0 24564.0 23286.0 True False 39707.57129318594 80318.59561871241 26512.022367044643 42674.42114544869 28516.872390125936 25621.280574593467 23323.112996891698 30168.500585438785 21797.34364961263 27310.95407335538 1.4539064137610893 2.9408930718048913 0.9707468401080072 1.5625386440483944 1.04415511495979 0.9381320222565801 0.8539838240087618 1.1046300507996984 0.7981172532847602 1.0 14.737192093244598 -5.28465097595278 24.78678173895378 1.0471553029900382 2.197399772048718 0.5916245436658649 0.38649456502534063 386.15792542506404 412362.8429395783 0.09512571187311947 0.1982289348207448 5.192171440890518e-06 5.28465097595278 1.15024446905868 FKIPSLGWS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FKIPSLGWSPSK 12 1 Q8IVF2-3;Q8IVF2 Q8IVF2-3 AHNAK2 Protein AHNAK2 1 FKIPSLGWS(0.966)PS(0.034)K 81.346 0.0062770000000000005 5651200.0 28554.0 21115.0 23916.0 33917.0 34911.0 28411.0 29730.0 35035.0 26564.0 19576.0 True False 33387.62823279297 23211.157655826417 24486.24814193507 32016.740450397625 28070.44016071042 26921.07714529294 26913.759173439543 34115.36837265093 26952.44824584937 23124.97383646925 1.4437909624848526 1.0037268720806616 1.0588659825127682 1.3845092615804655 1.2138582451687758 1.1641560044853778 1.1638395512904403 1.4752608419754958 1.1655125941523878 1.0 14.497164112918187 -5.73657612710348 24.999871293643746 1.2382719702556735 1.1522879437457425 0.015134903812181855 0.1634068740929924 770.6538840295559 774882.7514601729 0.043086046545342885 0.07458573660830743 1.8341036405003305e-06 5.73657612710348 -0.08598402650993098 FKIPSLGWSPS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 FKIPSLGWSPSK 12 1 Q8IVF2-3;Q8IVF2 Q8IVF2-3 AHNAK2 Protein AHNAK2 1 FKIPSLGWS(0.081)PS(0.919)K 93.90899999999999 0.0023940999999999997 4598000.0 27073.0 27855.0 35110.0 45936.0 47112.0 37442.0 32623.0 41924.0 29955.0 39120.0 True False 35681.65084661773 36858.58401578642 34644.41845953352 35346.16490412528 40571.31201231479 35100.745821057164 35526.38380087492 35445.60911767973 31538.360145655468 37750.4207072013 0.9451987601243096 0.9763754502676376 0.917722711708077 0.9363118143311875 1.0747247647117049 0.929810719019651 0.9410857716374504 0.9389460687763433 0.8354439382350827 1.0 15.204205102101362 -10.607607610689415 4.763461714452002 1.0000006356363385 0.947112861677982 0.08113527776385798 0.05567543366599178 1.3843788130627683e-06 2.660501924641968e-07 0.05465596778514763 0.013255440554046179 2.4682684347405525e-11 10.607607610689415 -0.05288777395835642 FKIPSLGWSPS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FKIPSLGWSPSK 12 1 Q8IVF2-3;Q8IVF2 Q8IVF2-3 AHNAK2 Protein AHNAK2 1 FKIPSLGWS(0.367)PS(0.633)K 99.663 0.0015455 6715500.0 31520.0 25168.0 29124.0 36215.0 36110.0 34042.0 30321.0 33948.0 32465.0 25481.0 True False 36855.71345162272 27666.51271048258 29818.426613385058 34185.99096061413 29034.504717803924 32256.777592483988 27448.77537497006 33056.90097087921 32939.739207254184 30100.503592514982 1.2244218219919598 0.9191378684229836 0.9906288285754772 1.1357282065245937 0.964585347503085 1.0716358114521778 0.9119041909250873 1.0982175387623543 1.0943251864877512 1.0 14.877500003555902 -11.803437368336212 2.275238512409722 0.8307161257466575 1.0389291817133375 0.016111754813046164 0.0947503871855005 9591462.64527 1635201.5939261692 8514866.414805023 0.022755728637060945 1.572398539151687e-12 11.803437368336212 0.20821305596667994 FKIPSLGWSPS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 FKIPSLGWSPSK 12 1 Q8IVF2-3;Q8IVF2 Q8IVF2-3 AHNAK2 Protein AHNAK2 1 FKIPSLGWS(0.423)PS(0.577)K 67.646 0.017171000000000002 2757500.0 37070.0 30778.0 29472.0 28777.0 30394.0 27902.0 24659.0 29307.0 28981.0 25304.0 True False 36541.37500219459 30706.73543199468 27048.925925209965 30893.35657725787 28606.28467690312 26708.696502738818 25935.722362586344 30668.710210463567 25716.854596540612 29677.762684539404 1.2312712178007534 1.034671506689799 0.911420655685109 1.0409597551419105 0.9638962674165977 0.8999565360313593 0.87391096957917 1.0333902368739 0.8665361627794732 1.0 14.857094715255387 -4.797512217079449 2.5097643838963246 0.9492554186035019 1.287794053158045 0.6764385435715187 0.05918985717598122 0.28403550323702575 2.34667750586027 0.015134224787833191 0.20636491591623998 1.5939980395378193e-05 4.797512217079449 0.338538634554543 FKMPFLSISS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 FKMPFLSISSPK 12 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 FKMPFLSIS(0.384)S(0.616)PK 125.73 0.00055385 0.0 6597.1 6856.0 5817.3 9281.0 11039.0 9108.3 7393.8 10548.0 10344.0 9597.8 True False 8694.84057179558 9072.0679236127 5740.158801043702 7141.408840020615 9506.425397010165 8538.756561132814 8051.833876311469 8918.048968926767 10890.762722305466 9261.783943342958 0.9387868066221867 0.9795162550874856 0.6197681608810929 0.7710619124465332 1.0264140747790869 0.9219343285663848 0.8693610135549363 0.9628867422821652 1.175881751175308 1.0 13.177074387255052 -8.014399541626702 4.053813939792123 1.0875029088861525 0.8741528704458816 0.3507976462539776 0.11491008796617848 0.2506682236140612 9.3244677123844 0.08378788349002857 0.03237199706979167 9.673874709912533e-09 8.014399541626702 -0.2133500384402709 FKMPFLSISS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 FKMPFLSISSPK 12 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 FKMPFLSIS(0.057)S(0.943)PK;FKMPFLSIS(0.235)S(0.764)PK 81.44800000000001 0.0062247 1481370.0 42382.0 18379.6 13303.0 15344.2 14808.400000000001 11840.400000000001 10648.8 8993.4 17637.300000000003 11558.3 True False 41777.62490809311 18337.04316543926 12209.278691065007 16472.66365475067 13937.399026434574 11334.013693320492 11200.142759021437 9411.266196020852 15650.80154499726 13556.136754533336 3.0818238016167965 1.3526746961524367 0.9006458781099325 1.2151443993984505 1.028124699448295 0.8360799170552968 0.826204615800735 0.6942439698296501 1.1545178267520386 1.0 13.726658475489003 -4.735913654322332 2.6698264944741386 0.9498158384575445 3.6625661416310566 0.9480866270154467 0.14859222950184353 0.1181277326574539 1.0012998285216606 0.04078119338880973 0.760185547530806 1.8369035170254004e-05 4.735913654322332 2.7127503031735123 up FKRPQFS(ph)PTGDCQAEAAAAANGTGGEEDDGPAAELLEK ddPTM_PC-9_AZD4547_30min_R2 1 FKRPQFSPTGDCQAEAAAAANGTGGEEDDGPAAELLEK 38 2 Q7Z4Q2 Q7Z4Q2 HEATR3 HEAT repeat-containing protein 3 1 FKRPQFS(0.487)PT(0.437)GDCQAEAAAAANGT(0.077)GGEEDDGPAAELLEK 51.632 0.0006539 5996500.0 16255.0 13828.0 20363.0 27682.0 21674.0 20121.0 17882.0 20549.0 16406.0 19605.0 True False 21423.75187499617 18297.63057872177 20092.973315052164 21300.342582636637 18664.939220472726 18862.83068921241 19473.463357975812 17373.624219044003 17273.187666487192 18918.634917297586 1.1324153126612808 0.9671749922079198 1.0620731042640326 1.1258921521426168 0.9865901690088167 0.9970503036646606 1.0293270863941106 0.9183339228751142 0.9130250539743786 1.0 14.207520373665718 -7.086743862980968 1.0233096356661162 0.9440240227359754 1.0600535199803407 0.41044582565490295 0.055292149491647014 0.5455947401201776 1.1565259018682692 0.03699192975076359 0.024517776689960944 8.189476424470304e-08 7.086743862980968 0.11602949724436529 FKRPQFS(ph)PTGDCQAEAAAAANGTGGEEDDGPAAELLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FKRPQFSPTGDCQAEAAAAANGTGGEEDDGPAAELLEK 38 2 Q7Z4Q2 Q7Z4Q2 HEATR3 HEAT repeat-containing protein 3 1 FKRPQFS(0.891)PT(0.104)GDCQAEAAAAANGT(0.005)GGEEDDGPAAELLEK;FKRPQFS(0.756)PT(0.244)GDCQAEAAAAANGT(0.001)GGEEDDGPAAELLEK 57.958999999999996 5.2597e-05 11612000.0 63960.0 58218.0 60317.0 73177.0 70723.0 69508.0 79050.0 83115.0 71961.0 56147.0 True False 74787.16473241715 63997.49829064183 61755.18603349629 69077.12993303483 56865.33583930349 65862.87811815922 71561.81172756138 80933.31931762196 73013.29348816324 66326.00664059255 1.1275692374738304 0.9648929813825753 0.9310855448924489 1.0414788019328538 0.8573610672423781 0.9930173917307742 1.0789404541621301 1.2202350694228215 1.1008245058956703 1.0 16.01728704618691 -7.340934613210697 3.784256665452002 1.1240389372055457 0.9787200181458822 0.3048319285700609 0.08309417876243243 0.24827239200654694 6.792330819156829 0.0361543138645732 0.023755024155988937 4.561055814209975e-08 7.340934613210697 -0.14531891905966354 FKRPQFS(ph)PTGDCQAEAAAAANGTGGEEDDGPAAELLEK ddPTM_PC-9_Lapatinib_30min_R1 1 FKRPQFSPTGDCQAEAAAAANGTGGEEDDGPAAELLEK 38 2 Q7Z4Q2 Q7Z4Q2 HEATR3 HEAT repeat-containing protein 3 1 FKRPQFS(0.766)PT(0.234)GDCQAEAAAAANGTGGEEDDGPAAELLEK 73.817 3.2921e-08 4947700.0 25138.0 21709.0 27281.0 24772.0 24329.0 23711.0 20034.0 20084.0 24822.0 18056.0 True False 24779.527510255393 21658.734144296974 25038.06148770538 26593.815516969502 22898.016052654333 22696.935803040637 21071.26249288516 21017.17596024671 22026.284972752193 21176.955541892316 1.1701175582692451 1.0227501352331596 1.18232582762782 1.2557903077409565 1.0812704407561045 1.0717752019709108 0.9950090536480527 0.9924550258733117 1.040106304665925 1.0 14.370207577929829 -6.809883681926541 2.1597209900609866 1.0085656167652046 1.1492360978627791 0.5601588656713571 0.05770511211552701 0.2543736970983161 2.436142607221081 0.024422683611874444 0.021785042298205305 1.5492314975273947e-07 6.809883681926541 0.14067048109757452 FKS(ph)DSGSLGDAK ddPTM_PC-9_AZD4547_30min_R2 1 FKSDSGSLGDAK 12 1 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 FKS(0.997)DS(0.001)GS(0.001)LGDAK 88.28200000000001 0.039189999999999996 4479000.0 11935.0 16451.0 12987.0 14285.0 15948.0 16032.0 13351.0 12695.0 17280.0 12247.0 True False 15730.081736578231 21768.464033161108 12814.783894444941 10991.813951049939 13733.895482518168 15029.516505613701 14539.2131356859 10733.279452078616 18193.38552218083 11818.236257696673 1.3310007850227188 1.8419384719089795 1.0843228731443968 0.9300722807848316 1.1620934954294821 1.2717224616173728 1.2302354444993584 0.9081963854875997 1.539433222138567 1.0 13.528727124697932 -5.278363072200934 24.827128793651298 1.1385909996811638 1.5864696380481065 0.4212770949337553 0.2089479608686323 575.3794547015318 844083.7284084557 0.052032752611529946 0.10875967817506635 5.267892790037512e-06 5.278363072200934 0.44787863836694264 FLDAGHK ddPTM_PC-9_AZD4547_30min_R2 2 FLDAGHK 7 0 P30101 P30101 PDIA3 Protein disulfide-isomerase A3 0 ; 114.78 0.0071446 9610900.0 103742.0 103830.0 133731.0 169383.0 150236.0 131714.0 112071.0 148293.0 123116.0 126997.0 False True 136729.7980323501 137391.01699368522 131957.63956171682 130334.36629126284 129378.3246621269 123477.9027582586 122045.1018897053 125377.72428413531 129623.66041370458 122550.87368487813 1.1156982722451334 1.1210937373401872 1.076758048261874 1.0635123387728662 1.05571115710529 1.0075644427942978 0.995872964590417 1.0230667519068533 1.057713066550738 1.0 16.90302124388308 -5.829583562338983 0.9383273910945475 1.0174596348945726 1.125715896337058 0.8110126019596623 0.018591020103233328 0.2973443167157588 0.5004673835032857 0.008280204490030195 0.02347499850008049 1.4805273604848647e-06 5.829583562338983 0.10825626144248535 FLDAGHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FLDAGHK 7 0 P30101 P30101 PDIA3 Protein disulfide-isomerase A3 0 ; 89.29799999999999 0.01401 7885600.0 102146.0 107623.0 109054.0 126447.0 127232.0 115056.0 120308.0 107006.0 104549.0 83599.0 False True 119437.30032453839 118307.10018437168 111654.26094959836 119362.5845367051 102301.80294255406 109022.26081548796 108911.55528550826 104197.20588222891 106077.83133772398 98754.83693067999 1.2094324089500168 1.1979879048093232 1.1306206806657277 1.20867583043543 1.0359168838926223 1.1039688202008282 1.1028478064518266 1.0551098976080446 1.0741532732435608 1.0 16.591563791473476 -1.5228787452803376 0.14989255146606573 0.9812164839507064 1.8686988635644535 0.7274164980075922 0.03681772808815031 35.05832794670269 0.3458088573851816 0.12799680721626264 6.761398751933415 0.029999999999999995 1.5228787452803376 0.8874823796137471 FLDAGHK ddPTM_PC-9_Lapatinib_30min_R1 2 FLDAGHK 7 0 P30101 P30101 PDIA3 Protein disulfide-isomerase A3 0 ; 99.375 0.0099553 10247300.0 142216.0 154332.0 143889.0 129620.0 143478.0 133272.0 144995.0 135213.0 141235.0 116926.0 False True 140187.97376077977 153974.65373612958 132059.00184760234 139152.68719964445 135038.90612860137 127572.26723220573 152502.1316340162 141495.4895993246 125327.62702951638 137136.50330589837 1.0222513363059489 1.1227838688045868 0.9629748364885016 1.0147020220374787 0.9847043119320458 0.930257547457233 1.1120462310012607 1.0317857476918673 0.9138896209855887 1.0 17.065253116515123 -5.268922653090405 24.968994762156502 0.9973063150189776 1.0725176036992914 0.23193863232501688 0.05701639061882619 768.9127108228985 2565592.3837429704 0.014930949832025454 0.03208325456747211 5.383656557395961e-06 5.268922653090405 0.07521128868031379 FLDGIYVSEK ddPTM_PC-9_Lapatinib_30min_R1 1 FLDGIYVSEK 10 0 D6RAN4;P32969;H0Y9V9;A0A2R8Y5Y7;H0Y9R4 D6RAN4 RPL9 60S ribosomal protein L9 0 152.97 0.00079435 7870400.0 53695.0 53357.0 56143.0 46351.0 55303.0 54813.0 51860.0 52959.0 50235.0 44741.0 False True 52929.299453542946 53233.45514474428 51527.13925824724 49759.8071624033 52050.186269881335 52468.775765343766 54545.05704707118 55419.668476334686 44577.00530199848 52474.422236364866 1.0086685512253788 1.0144648168770767 0.9819477197128402 0.9482678425360472 0.9919153761317732 0.999892395746719 1.0394598877407242 1.056127273335251 0.8494996876994014 1.0 15.679326756525288 -8.251246814632262 24.998039535934335 0.9247498353590363 1.0032726526539568 0.3491459903912847 0.0438216626863128 690.2092920565565 1692800.7556069235 0.030044187686629163 0.011085622063369369 5.607292164933347e-09 8.251246814632262 0.0785228172949205 FLEESVSMS(ph)PEER ddPTM_PC-9_AZD4547_30min_R2 5 FLEESVSMSPEER 13 0 A0A087WTB8;Q5TBK7;P15374 A0A087WTB8 UCHL3 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase isozyme L3 1 FLEESVS(0.009)MS(0.99)PEER;FLEES(0.001)VS(0.004)MS(0.995)PEER;FLEES(0.001)VS(0.024)MS(0.975)PEER;FLEES(0.009)VS(0.035)MS(0.956)PEER;FLEES(0.004)VS(0.006)MS(0.989)PEER 141.34 6.758899999999999e-05 31533700.0 83895.5 74555.9 105442.3 141484.0 125252.6 110121.9 92667.7 120289.0 98412.6 93156.4 True False 110572.52386519495 98654.636654912 104044.06620722497 108867.04970600978 107863.43850725194 103235.96018460231 100914.9457788778 101701.09901623378 103614.48912269522 89895.02279060119 1.2300183083857636 1.0974427014131272 1.1573951813726344 1.2110464664946077 1.1998822088126708 1.1484057401606884 1.1225865753874504 1.13133181191948 1.1526165287710284 1.0 16.455953619937702 -11.044682755892683 0.2911909550860216 0.871747822054335 1.1776407897763617 0.646569576823594 0.03703186275322689 14.819245489519226 0.8231684158480548 1.4277548667059745 0.04434030515878575 9.02229959289354e-12 11.044682755892683 0.3058929677220267 FLEESVSMS(ph)PEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 FLEESVSMSPEER 13 0 A0A087WTB8;Q5TBK7;P15374 A0A087WTB8 UCHL3 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase isozyme L3 1 FLEES(0.004)VS(0.025)MS(0.971)PEER;FLEES(0.008)VS(0.074)MS(0.918)PEER;FLEES(0.001)VS(0.029)MS(0.97)PEER;FLEESVS(0.004)MS(0.996)PEER 107.53 0.00087867 33721400.0 105569.0 101454.0 116724.0 131023.0 137104.0 111919.0 132000.0 116413.0 110884.0 98647.0 True False 123439.74661720697 111525.6826338723 119507.14283823491 123682.20609229716 110239.45540929901 106049.77061786076 119496.00440275852 113357.28209976907 112505.46872808179 116530.9202107776 1.0592874954898914 0.9570479871964285 1.025540196731254 1.061368140477948 0.9460103396583605 0.9100569224549258 1.025444613211822 0.9727656993931899 0.9654559367126365 1.0 16.830353283531366 -4.747373272439712 24.94973874397855 0.9853829834469424 1.059287687161621 0.21885323032027226 0.042176195785428194 1225.618723726127 2173813.081081955 0.011037503630127822 0.22614591042519366 1.7890675046187358e-05 4.747373272439712 0.07390470371467861 FLEESVSMS(ph)PEER ddPTM_PC-9_Lapatinib_30min_R1 4 FLEESVSMSPEER 13 0 A0A087WTB8;Q5TBK7;P15374 A0A087WTB8 UCHL3 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase isozyme L3 1 FLEES(0.001)VS(0.007)MS(0.992)PEER;FLEES(0.05)VS(0.162)MS(0.788)PEER;FLEES(0.003)VS(0.061)MS(0.937)PEER;FLEES(0.005)VS(0.005)MS(0.99)PEER 138.31 6.3485e-05 14245000.0 76395.0 69769.0 80909.0 69608.0 73765.0 72804.0 63347.0 61033.0 73234.0 63073.0 True False 75305.59329087268 69607.45416709452 74256.97433777196 74727.20452548089 69426.2877275699 69690.34263441313 66626.79770074847 63868.81599192076 64985.615731791666 73975.08401051023 1.0179859110423373 0.9409580955285544 1.0038106117895274 1.010167214069859 0.9385090758086325 0.942078587224202 0.9006653874334536 0.8633828112023018 0.8784797827679202 1.0 16.17475180937997 -6.72123986737676 1.6527385745420502 0.9010461838057902 0.9893962176346709 0.42304381670523394 0.0408792644764103 0.32134688711512965 1.8184987903378345 0.016845959765671464 0.01582838068574188 1.9000285756960326e-07 6.72123986737676 0.08835003382888074 FLENGS(ph)QEDLLHGNPGSTYLASNSTSAPNWK ddPTM_PC-9_AZD4547_30min_R2 2 FLENGSQEDLLHGNPGSTYLASNSTSAPNWK 31 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 FLENGS(0.994)QEDLLHGNPGS(0.003)T(0.001)Y(0.001)LASNSTSAPNWK;FLENGS(0.984)QEDLLHGNPGS(0.007)T(0.006)Y(0.002)LAS(0.001)NSTSAPNWK 78.226 5.845000000000001e-07 27936000.0 38972.0 43804.0 101833.0 146581.0 136405.0 128376.0 121443.0 154175.0 115552.0 126731.0 True False 51364.28533204251 57962.78636609256 100482.62788349978 112789.01510387483 117467.52027168842 120348.62842593975 132251.19173373518 130350.79633904847 121659.84281591656 122294.18626391409 0.4200059455091105 0.4739619121468892 0.8216468088405741 0.9222761813098225 0.9605323348584242 0.9840911665761791 1.0814184694629196 1.0658789294999518 0.9948129713490338 1.0 16.89999629573807 -5.318619586211009 1.182403660958814 1.0242690698981771 0.32200242899062925 0.9682538661518233 0.03988515725407868 0.11727162855341174 0.2477604368122068 0.013749278018619653 0.08073092819226232 4.801538481068957e-06 5.318619586211009 -0.7022666409075479 down FLENGS(ph)QEDLLHGNPGSTYLASNSTSAPNWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FLENGSQEDLLHGNPGSTYLASNSTSAPNWK 31 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 FLENGS(0.997)QEDLLHGNPGS(0.001)T(0.001)YLASNSTSAPNWK 82.765 1.2360999999999998e-07 6548600.0 4501.4 8651.2 10266.0 19339.0 21581.0 20277.0 17129.0 19329.0 19277.0 14577.0 True False 5263.398113297414 9510.033962211015 10510.780374021806 18255.498527883945 17352.357970504763 19213.638424381577 15506.417116779208 18821.634230768374 19558.88965649896 17219.69470853149 0.3056615231795989 0.5522765718662407 0.6103929571303168 1.0601522754546435 1.007704158768131 1.1157943708991651 0.9005047638328083 1.093029496129406 1.1358441591190649 1.0 14.07177194467724 -5.543267717292964 1.715743724024805 1.0521633425767405 0.38387899608563036 0.8963201896189388 0.08758820661810335 0.10974413144884836 0.6260339764729071 0.02580536486712228 0.07256635447850741 2.862412914828854e-06 5.543267717292964 -0.6682843464911101 down FLENGS(ph)QEDLLHGNPGSTYLASNSTSAPNWK ddPTM_PC-9_Lapatinib_30min_R1 2 FLENGSQEDLLHGNPGSTYLASNSTSAPNWK 31 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 FLENGS(0.995)QEDLLHGNPGS(0.003)T(0.001)Y(0.001)LASNSTSAPNWK;FLENGS(0.97)QEDLLHGNPGS(0.021)T(0.007)Y(0.001)LAS(0.001)NSTSAPNWK 75.708 8.401100000000001e-07 17655900.0 113265.0 79817.0 112041.0 84747.0 102916.0 104462.0 70007.0 77071.0 107653.0 67973.0 True False 111649.82032974313 79632.1886404419 102829.42147076732 90979.57708770438 96862.68322064096 99994.40377281552 73631.61991311816 80652.00002151827 95527.98550365359 79722.04248167075 1.4004887086957543 0.9988729109486939 1.2898493097992225 1.141209811685669 1.21500503757052 1.2542880320183176 0.9236042833454391 1.0116649989250002 1.1982631469284903 1.0 16.282691052100105 -7.248031067339122 24.85740885550223 1.0343551861073514 1.206549026805684 0.37178132113587714 0.11624429386600399 810.463616809467 1502504.9168131736 0.04245556274360531 0.03268793173332178 5.648965633828116e-08 7.248031067339122 0.17219384069833255 FLENGSQEDLLHGNPGS(ph)TYLASNSTSAPNWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FLENGSQEDLLHGNPGSTYLASNSTSAPNWK 31 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 FLENGS(0.233)QEDLLHGNPGS(0.603)T(0.132)Y(0.027)LAS(0.004)NS(0.001)TSAPNWK 77.73100000000001 6.3468e-07 9060700.0 16767.0 23872.0 43650.0 56571.0 67330.0 62530.0 68433.0 60297.0 61124.0 47878.0 True False 19605.321936654767 26241.854395448172 44690.78154354683 53401.51027565656 54137.16983244914 59250.81672222616 61950.530827984796 58714.26763995241 62017.82286475293 56557.902397960526 0.3466416027720599 0.4639821012243631 0.7901774933074317 0.9441918460820112 0.9571990391638238 1.0476134052022894 1.095347037308419 1.038126683461826 1.0965368274865386 1.0 15.787440994460255 -5.259839923516148 1.0168806611127021 1.0551495578363623 0.20194619443441925 0.9789782600889347 0.03657657293442979 0.12311691459787055 0.17024491451547166 0.012811247487453607 0.09666653456234998 5.4974346631190125e-06 5.259839923516148 -0.8532033634019431 down FLES(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 1 FLESPSR 7 0 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 FLES(0.992)PS(0.008)R 106.68 0.010019 15397000.0 21782.0 22250.0 28033.0 36648.0 36761.0 24676.0 24489.0 33637.0 24831.0 26014.0 True False 28708.222906254476 29441.87737753539 27661.264103563197 28199.369805955757 31657.36969104905 23133.005819144455 26668.473558520855 28439.17455136419 26143.515966508796 25103.25777804537 1.143605469859052 1.1728309384323998 1.1018993768910341 1.1233350689095885 1.2610861096576769 0.9215140928591331 1.0623511017699216 1.1328878029622245 1.041439170870213 1.0 14.615586981783144 -6.756790145263258 24.999976099730745 1.0418634681045302 1.1559075512155446 0.5030471520015005 0.0635767666331472 116.64457827557347 627224.2824203316 0.021851592729840528 0.021163760103953617 1.7506924335422815e-07 6.756790145263258 0.11404408311101433 FLES(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FLESPSR 7 0 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 FLES(0.982)PS(0.018)R 88.177 0.017446 9597000.0 24980.0 25669.0 35842.0 31228.0 37911.0 34542.0 28469.0 35014.0 26821.0 24731.0 True False 29208.620622510625 28217.248679488926 36696.60921154194 29478.396402542 30482.611696390588 32730.556712284295 25772.210222288923 34094.9196003996 27213.20638465313 29214.534529511708 0.9997975696995922 0.9658633667767204 1.2561079545687113 1.0090318698305374 1.043405694709868 1.1203518125274528 0.8821708316541739 1.1670533229258833 0.9314954635735547 1.0 14.834398682787054 FLEYGKDT(ph)LQRT(ph)ES(ph)ETIPLVMK ddPTM_PC-9_Lapatinib_30min_R1 1 FLEYGKDTLQRTESETIPLVMK 22 2 Q95460-3 Q95460-3 3 FLEY(0.015)GKDT(0.985)LQRT(0.844)ES(0.845)ET(0.311)IPLVMK 47.7 0.037308 0.0 1057.5 1054.3 2848.2 2815.7 3103.4 3840.0 1244.1 1330.6 1130.8 2482.7 True False 1042.4198560782506 1051.8588331259984 2614.0319903699433 3022.7759708998497 2920.8641135191533 3675.7721514772043 1308.513410571949 1392.424533594118 1003.4373961481018 2911.8313870101933 0.3579945805682743 0.3612361752189315 0.8977278018333252 1.038101307783337 1.0031020774586246 1.2623574867263894 0.4493781530102616 0.47819545451903034 0.3446069716208431 1.0 11.507711101679764 -3.749098149757143 12.134014276835945 0.7241166241703548 0.7075581938383226 0.0 0.33437831351893427 0.0 0.0 0.0835029678030502 0.0 0.00017819759986267586 3.749098149757143 -0.016558430332032192 FLGS(ph)VIMRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FLGSVIMRR 9 1 H7C3E5;O60244 H7C3E5 MED14 Mediator of RNA polymerase II transcription subunit 14 1 FLGS(1)VIMRR 72.321 0.014901 0.0 11877.0 14843.0 9179.1 18678.0 13966.0 12416.0 16143.0 12789.0 12811.0 12360.0 True False 13887.541518557207 16316.51494603039 9397.964555930603 17631.53221489304 11229.462555769866 11764.883102881175 14613.818174801014 12453.302301065582 12998.336638969147 14600.77015829383 0.9511513001023799 1.1175105675341344 0.6436622489117245 1.2075754925076752 0.7691007004442896 0.8057714062568297 1.0008936526200827 0.8529209189688943 0.8902500688695223 1.0 13.833756849630534 FLHAIMPS(ph)T(ph)FIPLY(ph)TMVT(ph)FSR ddPTM_PC-9_AZD4547_30min_R2 1 FLHAIMPSTFIPLYTMVTFSR 21 0 H0Y320;O15229-2;O15229 H0Y320 KMO Kynurenine 3-monooxygenase 4 FLHAIMPS(0.999)T(0.999)FIPLY(0.757)T(0.299)MVT(0.892)FS(0.053)R 49.765 0.015577 1894000.0 1053.4 1201.7 1027.9 3005.5 2758.9 2251.3 2597.7 3010.6 880.83 2158.2 True False 1388.359287918853 1590.1260244756975 1014.2693743820718 2312.628409512115 2375.8743570804745 2110.5258551077936 2828.8902675882914 2545.380946705623 927.3888755499149 2082.6420749049544 0.6666336499430482 0.7635138287255943 0.4870108918875847 1.1104300817593231 1.1407982128608933 1.0133886569078903 1.358318023857937 1.2221883814681822 0.4452944107509392 1.0 11.024199202230939 -5.7718588197712695 24.999171342030024 1.0669144953242444 0.6514988886877409 0.37862572769781666 0.23451340318837907 204.10955007967587 489716.46333912073 0.06608180501411699 0.09921847053538116 1.6909905486491356e-06 5.7718588197712695 -0.41541560663650356 FLIATGERPR ddPTM_PC-9_AZD4547_30min_R2 1 FLIATGERPR 10 1 Q16881;Q16881-5;A0A182DWI3;Q16881-2;F8W809;Q16881-3;Q16881-6;Q16881-4;A0A087WSW9;E9PIR7;A0A087WSY9;Q16881-7;E2QRB9;E9PKD3 Q16881 TXNRD1 Thioredoxin reductase 1, cytoplasmic 0 112.71 0.0018300999999999999 12844000.0 38793.0 44176.0 45210.0 71451.0 57679.0 57203.0 45952.0 57310.0 46938.0 62857.0 False True 51128.3670554738 58455.02809123604 44610.48586031079 54979.07585694563 49671.26646201192 53626.087367179454 50041.63897918046 48454.056352786574 49419.046854173816 60656.39556218181 0.8429179904542734 0.9637075785571689 0.735462195648906 0.9064019605415544 0.8188957817497001 0.8840961760117242 0.8250018570239696 0.798828481377763 0.8147376116919436 1.0 15.888372149534817 -5.226808316400348 24.999903399291547 0.8422676650644089 0.9033127359955233 0.08077750486614677 0.0727557751058837 1366.687265608203 986596.834352823 0.016936661108123443 0.044806713146079695 5.931870804866234e-06 5.226808316400348 0.06104507093111444 FLIATGERPR ddPTM_PC-9_Lapatinib_30min_R1 1 FLIATGERPR 10 1 Q16881;Q16881-5;A0A182DWI3;Q16881-2;F8W809;Q16881-3;Q16881-6;Q16881-4;A0A087WSW9;E9PIR7;A0A087WSY9;Q16881-7;E2QRB9;E9PKD3 Q16881 TXNRD1 Thioredoxin reductase 1, cytoplasmic 0 116.52 0.0013400999999999999 15017000.0 98497.0 51152.0 51571.0 45853.0 51319.0 50421.0 40212.0 31042.0 58709.0 42903.0 False True 97092.41471786248 51033.560686769524 47331.03144981688 49225.182581124 48300.51731703596 48264.61136709172 42293.98060117287 32484.324644392455 52096.57418682249 50318.726385345944 1.929548335033738 1.0142061286676716 0.9406245914761635 0.978267657336009 0.9598914914329443 0.9591779211078674 0.8405216832652173 0.6455712808711449 1.0353317329191045 1.0 15.618807786249981 -4.753719997803539 3.8284337091201266 0.9120533632577575 2.0635313413714047 0.8926282021241125 0.10437645526230646 0.08656507717753213 2.210965154112667 0.027518573915177504 0.29314063856227507 1.763112409544626e-05 4.753719997803539 1.1514779781136473 FLIDGFPR ddPTM_PC-9_Lapatinib_30min_R1 1 FLIDGFPR 8 0 Q5T0D2;A0A494BXC7;P30085-2;P30085;P30085-3 Q5T0D2 CMPK1 UMP-CMP kinase 0 95.352 0.029731999999999998 1142000.0 17863.0 17478.0 15633.0 17048.0 17295.0 16403.0 14198.0 14185.0 17445.0 14653.0 False True 17608.270344326997 17437.53076484513 14347.715085125114 18301.766790460853 16277.74210327827 15701.481927260567 14933.10296865245 14844.08688488844 15480.160396006047 17185.751526104796 1.0245854141193886 1.0146504642731444 0.8348610803159371 1.0649384033430749 0.9471649859799685 0.9136337100772315 0.8689234768679962 0.8637438323451019 0.9007555108947088 1.0 14.068925321121622 -6.695857892874089 3.4358945529197062 0.8972888980606364 0.9788321154292715 0.2077625268686718 0.06662755873962574 0.3504522480549376 8.325197647998262 0.02317320185455565 0.02245261099363025 2.0143832759404284e-07 6.695857892874089 0.08154321736863512 FLIPNASQAESK ddPTM_PC-9_AZD4547_30min_R2 1 FLIPNASQAESK 12 0 P63104;E7EX29;E7ESK7;B0AZS6;P63104-2 P63104 YWHAZ 14-3-3 protein zeta/delta 0 86.882 0.040918 4073600.0 22092.0 15297.0 24733.0 30164.0 27690.0 24293.0 24287.0 32053.0 28088.0 30269.0 False True 29116.796457853892 20241.456100861054 24405.024259744878 23210.155829154362 23845.72146419165 22773.95486969022 26448.49594984671 27099.94535466531 29572.674337211505 29209.291523166554 0.9968333684081553 0.6929800431758879 0.8355226363634564 0.794615501397761 0.8163745240201757 0.7796818643008742 0.9054822822001625 0.927785096505053 1.0124406582664542 1.0 14.834139745302645 -7.7278076201502 1.617164325796997 1.0019631582236355 0.8131755951003418 0.5025938116034806 0.0728629557237207 0.30278253068324945 1.5075482176666968 0.05192180586931674 0.02098440747958632 1.8715109818190024e-08 7.7278076201502 -0.1887875631232937 FLIPNASQAESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FLIPNASQAESK 12 0 P63104;E7EX29;E7ESK7;B0AZS6;P63104-2 P63104 YWHAZ 14-3-3 protein zeta/delta 0 ; 88.338 0.037272 10200000.0 81679.0 73462.0 70965.0 86756.0 103782.0 79428.0 91431.0 77967.0 88256.0 64201.0 False True 95505.64146621467 80754.82186655553 72657.07473626136 81895.34258674688 83446.6621053208 75262.65585499736 82769.99377688381 75920.44886286504 89546.5770360519 75840.13308516354 1.2593021343853397 1.0648032721128418 0.9580293675733953 1.079841757328982 1.1002968838624745 0.9923855984071426 1.0913745850622187 1.0010590141978168 1.1807281104780882 1.0 16.210673875446183 -4.765697575209715 5.4914276016283035 1.050173919940564 1.2688899612436841 0.49940439730781183 0.06237953390193609 0.11607389201593869 11.076893099024593 0.014685021537902927 0.09624836989385305 1.7151512524448858e-05 4.765697575209715 0.21871604130312017 FLIPNASQAESK ddPTM_PC-9_Lapatinib_30min_R1 2 FLIPNASQAESK 12 0 P63104;E7EX29;E7ESK7;B0AZS6;P63104-2 P63104 YWHAZ 14-3-3 protein zeta/delta 0 ; 167.11 0.0025041 22708100.0 158134.0 159610.0 177732.0 184801.0 172611.0 159236.0 183469.0 151728.0 166473.0 171246.0 False True 155878.9801617759 159240.4328514088 163119.5610253603 198391.88201806438 162458.36034628312 152425.84747724613 192968.1270992883 158777.8367902967 147723.05770159417 200845.6429290478 0.7761133270729843 0.7928498250154385 0.8121638022438212 0.9877828521684672 0.8088717184851968 0.7589203592088537 0.9607782587917908 0.7905465833101876 0.7355054137459177 1.0 17.61572763886805 -12.003230411304855 2.3319631105806593 3.2568680698739922 0.8288973501930624 0.30531168552099996 0.07905277379371477 2639407.1834535026 736493.0363887366 30910285.821060825 0.01990987724137542 9.925892987517193e-13 12.003230411304855 -2.4279707196809297 FLIVAHDDGR ddPTM_PC-9_AZD4547_30min_R2 2 FLIVAHDDGR 10 0 Q16658 Q16658 FSCN1 Fascin 0 ; 109.83 0.0015335999999999998 102474000.0 269860.0 254700.0 366970.0 482930.0 421820.0 340130.0 297740.0 373900.0 296740.0 307830.0 False True 355669.8665633013 337026.79407003423 362103.73802606174 371597.94969412324 363257.57414320344 318861.61733123625 324238.28320119175 316122.34636724694 312425.07059328334 297052.9653961599 1.1973281131496798 1.1345680175943165 1.2189871174763325 1.2509484603143 1.2228713948664032 1.0734167117503493 1.0915167359759448 1.0641952217028214 1.0517487013692075 1.0 18.180360665064377 -6.789871769191444 7.3598782557543 1.061810981026565 1.204414255912101 0.8144214474663791 0.035460791614957146 0.08794345570283008 16.703558411086117 0.013313799471544159 0.011959191248004875 1.622289027518225e-07 6.789871769191444 0.14260327488553592 FLIVAHDDGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 FLIVAHDDGR 10 0 Q16658 Q16658 FSCN1 Fascin 0 ;;; 109.83 0.0015335999999999998 101227000.0 214985.0 225619.0 254949.0 277591.0 287748.0 253880.0 265183.0 255056.0 241217.0 190656.0 False True 251377.7143526997 248016.96325597435 261027.95105946693 262038.47623216503 231365.84501630114 240566.08586980298 240062.94648133888 248361.05025417064 244744.3422872699 225220.42356793408 1.116140847132701 1.101218794134645 1.1589888116018576 1.163475639024919 1.0272862529561553 1.0681361932402198 1.0659022067282802 1.1027465729779011 1.086688047247397 1.0 17.780978135088326 -6.257460122084365 24.97900451745775 1.0644531395200247 1.1342628488894073 0.5707869588239876 0.0322445453823416 283.35264172276675 1778685.497002934 0.009941282340221989 0.012356514457916553 5.527641616876487e-07 6.257460122084365 0.06980970936938258 FLIVAHDDGR ddPTM_PC-9_Lapatinib_30min_R1 4 FLIVAHDDGR 10 0 Q16658 Q16658 FSCN1 Fascin 0 ;;; 99.973 0.0034974000000000003 77476300.0 237629.0 206989.0 239156.0 194008.0 221656.0 204379.0 178958.0 186490.0 209205.0 156511.0 False True 234240.36688417828 206509.7296878665 219493.5168488565 208275.99551171612 208618.62987246312 195638.18660071876 188223.5695917811 195155.00621521645 185642.12987368557 183563.71781220174 1.276071163059697 1.1250029807041722 1.1957347533863605 1.1346250664022655 1.136491635486999 1.0657780793090605 1.025385472876218 1.0631458576954373 1.0113225646454285 1.0 17.48592140625447 -5.723238157678888 0.3344702180199488 0.990256651628163 1.3172173281855413 0.8294984089231162 0.03434171778531436 1.4558487969312877 0.21047822890016013 0.036826246190201466 0.1836554599800345 1.8913061829079011e-06 5.723238157678888 0.32696067655737826 FLLGPPQGGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 FLLGPPQGGSPR 12 0 Q8IY92;Q8IY92-2 Q8IY92 SLX4 Structure-specific endonuclease subunit SLX4 1 FLLGPPQGGS(1)PR 103.97 0.0019659000000000005 5841500.0 21943.0 19336.0 33616.0 33777.0 30436.0 19919.0 18138.0 27904.0 28589.0 29409.0 True False 28920.41755724643 25585.983863911177 33170.22987569579 25990.23449944794 26210.486763601915 18673.46178114518 19752.246862038115 23592.07797013012 30100.15617439974 28379.399861402926 1.0190637468898456 0.9015688840802126 1.1688136478463231 0.9158133937425385 0.9235743846454337 0.6579935401150538 0.6960065032559737 0.831309967277224 1.0606339923113424 1.0 14.79255646062753 -6.229287408394846 2.6453284012372533 0.8300050708486174 1.0157494410148176 0.21777719675818874 0.13263336432215772 0.39167737958189147 5.431237533171486 0.044265212351997166 0.05711802381609206 5.89810624764546e-07 6.229287408394846 0.18574437016620016 FLLGPPQGGS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FLLGPPQGGSPR 12 0 Q8IY92;Q8IY92-2 Q8IY92 SLX4 Structure-specific endonuclease subunit SLX4 1 FLLGPPQGGS(1)PR 98.0 0.0037954 4127800.0 36020.0 36725.0 41867.0 41211.0 48732.0 43637.0 41723.0 46322.0 36527.0 35315.0 True False 42117.474572571395 40370.81529293038 42865.26806148167 38902.08127786471 39183.31442558905 41348.59890145183 37770.69539163866 45106.09658221598 37061.13827270514 41717.329946613805 1.0095918081638893 0.9677228946481816 1.0275170562530462 0.9325160869031693 0.939257485455863 0.991161202175838 0.9053958016961847 1.081231628197174 0.8883871120259313 1.0 15.348359202890121 -5.759443558772647 24.999826391206007 0.9637872546050389 0.9982218102018936 0.0998895785357714 0.05333469067168691 138.17206410639724 1730708.8009371455 0.013811200885409694 0.022476563282173765 1.7400288187578658e-06 5.759443558772647 0.03443455559685471 FLLGPPQGGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 FLLGPPQGGSPR 12 0 Q8IY92;Q8IY92-2 Q8IY92 SLX4 Structure-specific endonuclease subunit SLX4 1 FLLGPPQGGS(1)PR;FLLGPPQGGS(1)PR 109.6 0.0012929999999999999 7368300.0 60280.0 41921.0 51446.0 41731.0 49595.0 46015.0 33447.0 37872.0 54567.0 36427.0 True False 59420.3961460019 41823.93450011858 47216.308467302915 44800.036950535046 46677.919607521566 44047.045716204084 35178.72200257209 39631.67137853331 48421.08984401613 42723.35841407352 1.390817537565778 0.9789477244453081 1.1051637844029925 1.048607567699487 1.0925620396018627 1.030982753960993 0.8234072251909824 0.9276347377569042 1.1333633787568937 1.0 15.382737438955271 -4.758190468051178 24.99969254922535 1.0140739146412214 1.3908180573963398 0.6267836773358185 0.0868468044047882 64.38847836064988 495374.34318736853 0.023159411247434435 0.1615868891247324 1.7450566575009572e-05 4.758190468051178 0.37674414275511836 FLLSLPEHR ddPTM_PC-9_Lapatinib_30min_R1 1 FLLSLPEHR 9 0 Q15008;Q15008-4;C9J7B7 Q15008 PSMD6 26S proteasome non-ATPase regulatory subunit 6 0 117.31 0.0015659 2725300.0 23897.0 18374.0 20754.0 18494.0 21924.0 21054.0 17188.0 18528.0 21090.0 18081.0 False True 23556.224397826907 18331.456131895204 19047.68623275675 19854.110454175454 20634.47342424242 20153.56949927113 18077.91053847009 19388.87851978942 18714.622112454424 21206.276758581927 1.110813777731821 0.864435390549012 0.8982098295519216 0.9362374489496715 0.9730361278951004 0.9503586946782263 0.8524792326476723 0.9142990417656873 0.8825039079470111 1.0 14.372203724913598 -7.124100250267896 16.65271592965588 0.9046142817671879 0.9487215129817819 0.07469636508310196 0.0700569393648119 4.510511549811366 587.6032426193876 0.026011387056378142 0.02014845554081884 7.514494133419718e-08 7.124100250267896 0.04410723121459392 FLMECRNS(ph)PVTK ddPTM_PC-9_AZD4547_30min_R2 1 FLMECRNSPVTK 12 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 FLMECRNS(0.92)PVT(0.08)K 147.7 0.00067203 21259000.0 30339.0 20376.0 30016.0 50238.0 48736.0 32248.0 25540.0 30038.0 28332.0 35637.0 True False 39986.17090959757 26962.14352560273 29617.96822789399 38656.405269362716 41969.84764459529 30231.52746214014 27813.010522464087 25396.31730457169 29829.571679075638 34389.35947705861 1.1627483476763394 0.7840257549312416 0.8612538493964201 1.1240804090913843 1.2204312113633193 0.8790953923497123 0.8087679138373701 0.738493466896752 0.8674070157943813 1.0 15.06967462458319 -6.980815539553452 24.991306317331794 0.8335972308654508 1.0163253003323507 0.27257367010003175 0.13828034310865844 334.6988455110174 436005.67094381794 0.051631429002866235 0.0455287642165903 1.0451640436240857e-07 6.980815539553452 0.1827280694668999 FLMECRNS(ph)PVTK ddPTM_PC-9_Lapatinib_30min_R1 1 FLMECRNSPVTK 12 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 FLMECRNS(0.999)PVT(0.001)K 54.093999999999994 0.040766000000000004 52550000.0 111640.0 65821.0 113070.0 92210.0 121560.0 96089.0 84087.0 82120.0 145470.0 87850.0 True False 110047.99312773159 65668.5955185303 103773.82106282191 98991.43100354273 114410.0797961553 91979.49746439929 88440.61341914906 85935.5949937989 129085.63673298922 103034.75544723308 1.0680667183617492 0.6373441197922869 1.0071729739385593 0.9607576644779727 1.1104027888409735 0.8927036034118071 0.8583570954797084 0.8340447320012214 1.2528358627404859 1.0 16.652771540521094 -5.868969410559964 0.22680256089345577 1.035475586443376 0.8212463475450038 0.05093192501019306 0.1566807375647015 24.0337155962278 1.7548498484863881 0.3147552748960381 1.4701615579345322 1.352167799493414e-06 5.868969410559964 -0.2142292388983722 FLMPEAYPS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 FLMPEAYPSSPR 12 0 O43166-3;O43166-2;O43166 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 FLMPEAYPS(0.5)S(0.5)PR 86.11399999999999 0.0081877 19298000.0 56680.0 52673.0 74084.0 90552.0 78270.0 75158.0 60008.0 80570.0 66772.0 77270.0 True False 74703.06098276126 69698.5171733448 73101.5977543744 69676.63541445395 67403.56153854389 70458.35837879952 65348.5957491004 68119.75781441313 70301.43160226024 74564.80081915761 1.0018542282965253 0.9347375223650762 0.9803767588901373 0.9344440627346547 0.9039595197473683 0.94492786951423 0.8764000578180405 0.9135645380401983 0.9428233004036672 1.0 16.186207129764533 -3.8793513037630487 0.6685950457509708 0.9250322394625922 1.17511586344992 0.222954567432867 0.034231641314728556 12.54275493667124 1.733830931091482 0.013999891515710513 3.147544779259098 0.00013202272613181207 3.8793513037630487 0.25008362398732775 FLMPEAYPS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FLMPEAYPSSPR 12 0 O43166-3;O43166-2;O43166 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 FLMPEAYPS(0.808)S(0.192)PR;FLMPEAYPS(0.5)S(0.5)PR 89.40299999999999 0.0066135000000000005 35299000.0 89336.0 95963.0 121855.0 117076.0 137011.0 118667.0 115650.0 132161.0 108704.0 92459.0 True False 104458.82033357126 105489.57244262694 124760.48533766069 110516.61128551299 110164.6780916931 112443.89361868566 104694.79476650804 128691.91378615468 110293.59035223654 109221.08479495879 0.9563979384536626 0.9658352381379747 1.1422747317688162 1.0118615054317242 1.008639296144199 1.0295072039412267 0.9585584593217695 1.1782698736947042 1.009819583455806 1.0 16.73689186542714 FLMPEAYPS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 2 FLMPEAYPSSPR 12 0 O43166-3;O43166-2;O43166 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 FLMPEAYPS(0.5)S(0.5)PR;FLMPEAYPS(0.5)S(0.5)PR 86.288 0.0081047 16717200.0 118013.0 102794.0 118271.0 98630.0 103697.0 94614.0 90750.0 80224.0 104144.0 74190.0 True False 116330.11297906646 102555.98680864477 108547.21491926252 105883.57922003474 97597.74633614608 90567.57977600633 95448.59095683985 83951.49991211091 92414.20603506186 87013.64264803898 1.3369180905298899 1.1786196243211302 1.2474735181277787 1.2168618161214404 1.1216372900387437 1.0408434473010475 1.0969382277549204 0.9648084755132696 1.0620657085793728 1.0 16.40895399473645 -6.410689032138942 0.8679736351424019 1.0142064601106089 1.270385315727754 0.8211224908856969 0.04715813191974017 0.24093330754133674 0.39668394485128616 0.024671005548560603 0.034082513126800135 3.884283928080636e-07 6.410689032138942 0.25617885561714515 FLMPEAYPS(ph)SPRK ddPTM_PC-9_AZD4547_30min_R2 1 FLMPEAYPSSPRK 13 1 O43166-3;O43166-2;O43166 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 FLMPEAYPS(0.531)S(0.468)PRK 74.257 0.0090239 6906700.0 26667.0 22147.0 37013.0 45458.0 37649.0 29857.0 34445.0 39202.0 30483.0 32198.0 True False 35146.55129194233 29305.58464181015 36522.18343613543 34978.36041909891 32422.086219044824 27990.037070116556 37510.53827119325 33144.23167234232 32094.269147722098 31070.75782030845 1.1311777940919696 0.943188602328053 1.1754519682897409 1.1257646376502726 1.0434919678030228 0.9008482262322461 1.2072617761088413 1.066733932401179 1.0329413055623853 1.0 14.92326980898049 -8.46029363097275 3.184698754966821 1.0012376535856218 1.072370343517201 0.06636232898763772 0.0906208570059873 0.7079993293356208 14.988133968017166 0.08634021959873338 0.02300253000143699 3.4650249732951787e-09 8.46029363097275 0.07113268993157917 FLMPEAYPS(ph)SPRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FLMPEAYPSSPRK 13 1 O43166-3;O43166-2;O43166 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 FLMPEAY(0.006)PS(0.497)S(0.497)PRK 52.42 0.034538 13867000.0 51804.0 39966.0 55593.0 60528.0 66203.0 62970.0 57558.0 70215.0 66994.0 50350.0 True False 60573.394024361136 43933.56035390762 56918.54795762655 57136.81239442365 53230.997392211946 59667.74234765042 52105.68955616657 68371.93064894216 67973.66050980403 59478.0564296193 1.0184158269535581 0.7386515799468739 0.9569671804084348 0.9606368436405441 0.8949686756358703 1.0031891747884463 0.8760489613143885 1.1495320249720504 1.1428359396752923 1.0 15.860069884620307 -7.762046842608454 24.999999991756916 1.1096380179429237 0.9192710756199747 0.4810983268634983 0.08354661891832334 12.625321227198057 519506.60507830826 0.04092648117916228 0.021526557908238812 1.7296297928549886e-08 7.762046842608454 -0.19036694232294904 FLMPEAYPSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 FLMPEAYPSSPR 12 0 O43166-3;O43166-2;O43166 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 FLMPEAYPS(0.059)S(0.941)PR 106.54 0.0016587 3424300.0 22828.0 13889.0 23048.0 31789.0 25926.0 23839.0 23244.0 34081.0 22753.0 26505.0 True False 30086.829148102897 18378.347635801736 22742.368460704318 24460.537185154117 22326.622415335212 22348.3435614599 25312.670970405456 28814.564553469198 23955.677128829866 25577.068017494126 1.176320488631621 0.7185478657378308 0.8891702694440606 0.9563464103244231 0.8729156289557629 0.8737648719616395 0.9896627304228995 1.126578094633861 0.9366076327609065 1.0 14.642563272421901 -7.4289034051614635 5.100422440664936 1.0298221783652035 0.9051617239302054 0.14915045814847916 0.11504641534502659 0.3587932073144277 14.864676079997881 0.047547146962549976 0.031189785924891623 3.7247454202348245e-08 7.4289034051614635 -0.12466045443499807 FLMPEAYPSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 FLMPEAYPSSPR 12 0 O43166-3;O43166-2;O43166 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 FLMPEAYPS(0.188)S(0.812)PR;FLMPEAYPS(0.225)S(0.775)PR;FLMPEAYPS(0.15)S(0.85)PR 148.13 8.5614e-05 25621500.0 138101.0 125337.0 130039.0 133407.0 124492.0 125520.0 111524.0 110843.0 112303.0 104599.0 True False 136131.65441537803 125046.78987718218 119347.6953850562 143218.19581270576 117169.62532068917 120151.80220141116 117298.167028877 115993.17043226554 99654.25353698283 122678.79778059322 1.109659182174615 1.0193023744887364 0.9728469592480472 1.1674241874202789 0.9550927090942234 0.9794015296457217 0.9561404998332369 0.9455029926174799 0.8123184718129616 1.0 16.904526408198116 -6.853812300582726 1.2224307827946295 0.9172396029419788 1.0555574699880461 0.41435458141060755 0.06973968835765773 0.4618947707870228 1.4445800752603373 0.03619277848442284 0.029917325217306116 1.4001923463825852e-07 6.853812300582726 0.1383178670460673 FLMPEAYPSS(ph)PRK ddPTM_PC-9_AZD4547_30min_R2 1 FLMPEAYPSSPRK 13 1 O43166-3;O43166-2;O43166 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 FLMPEAYPS(0.191)S(0.809)PRK 69.331 0.014102000000000002 7050900.0 21959.0 19379.0 33747.0 39635.0 37181.0 29404.0 24980.0 37619.0 25900.0 32878.0 True False 28941.505224425775 25642.882773000376 33299.49273010191 30497.76310464574 32019.059940776788 27565.36323172814 27203.171607327808 31805.847948621176 27269.02112410203 31726.95122728435 0.9122056833351462 0.8082365869100012 1.0495648476133823 0.9612572883592565 1.0092069581914707 0.8688311408889061 0.8574152433510154 1.0024867413440273 0.8594907505846759 1.0 14.953421272988946 -5.833561936953773 0.005673221202103122 1.8519318625779535 1.9466169787218674e-07 0.03415113266232861 0.07659552667973532 73575.99892823501 96.46141912141039 15312.446592193945 16179.569001491574 1.4670268517974104e-06 5.833561936953773 -1.8519316679162556 FLPGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 FLPGSPR 7 0 Q3MIP1 Q3MIP1 ITPRIPL2 Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2 1 FLPGS(1)PR 71.877 0.040286 3137800.0 23724.0 27206.0 39191.0 33764.0 35030.0 23614.0 29922.0 33872.0 21887.0 25674.0 True False 31267.73851014511 35999.80745767315 38671.301733055494 25980.231448599927 30166.689161814105 22137.412847028572 32585.000033405227 28637.860701126963 23043.90213680391 24775.161074557403 1.2620599485125121 1.453060480589278 1.560890022740098 1.0486402639488814 1.2176182859530822 0.8935325498150791 1.3152285846031515 1.1559101720850695 0.9301211833681521 1.0 14.59660681660641 -5.7707141427004505 24.99999249087769 1.094393408962132 1.4281091923303992 0.5645408361799601 0.13852673104594868 139.03491662279362 374767.119613729 0.038392460306598285 0.05783040125420607 1.6954533989221902e-06 5.7707141427004505 0.3337157833682671 FLPGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 FLPGSPR 7 0 Q3MIP1 Q3MIP1 ITPRIPL2 Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2 1 FLPGS(1)PR 73.665 0.035695 3279200.0 44251.0 45709.0 28702.0 15768.0 17641.0 22646.0 27528.0 20266.0 27828.0 11514.0 True False 43619.97262536046 45603.16361885261 26342.23235292399 16927.63132050603 16603.391063540428 21677.483370404385 28953.26514446155 21207.63234467036 24693.717598168885 13504.179558559385 3.2301090515130713 3.3769666214152085 1.9506725483539231 1.253510533320534 1.2295001700430341 1.6052425307588936 2.144022524205111 1.5704495228833268 1.8285981381606564 1.0 13.72111837165453 -5.34298527569023 3.6973100897117854 1.562606062791081 3.323506211653459 0.8348137443082154 0.311848503040167 0.0868406494623621 2.23756625232756 0.08693978023943916 0.20614976618979858 4.539570073368626e-06 5.34298527569023 1.760900148862378 FLPIS(ph)STPQPER ddPTM_PC-9_AZD4547_30min_R2 1 FLPISSTPQPER 12 0 J3KNG6;Q08AE8-3;Q08AE8-5;Q08AE8-2;Q08AE8;Q08AE8-4 J3KNG6 SPIRE1 Protein spire homolog 1 1 FLPIS(0.402)S(0.299)T(0.299)PQPER 82.85 0.011663 5741700.0 12527.0 20546.0 22961.0 28738.0 31626.0 27086.0 23944.0 34282.0 25785.0 23279.0 True False 16510.325422213275 27187.092701071528 22656.522137549106 22112.89809767399 27235.27580449709 25392.308138164473 26074.969614325764 28984.504621989683 27147.942458879188 22464.009295576143 0.7349678859625769 1.2102511329723098 1.0085698345046035 0.9843700564185888 1.2123960351930836 1.130355129578984 1.160744249667878 1.2902640949181599 1.2085083344505851 1.0 14.455327817289907 -4.755100298440998 24.999866922467803 1.1375961322735313 0.7349672171050284 0.5914960313823299 0.09942677953304428 158.59118944946198 625388.0844680457 0.026052574932347538 0.2387344919498565 1.7575176759443708e-05 4.755100298440998 -0.40262891516850285 FLPIS(ph)STPQPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FLPISSTPQPER 12 0 J3KNG6;Q08AE8-3;Q08AE8-5;Q08AE8-2;Q08AE8;Q08AE8-4 J3KNG6 SPIRE1 Protein spire homolog 1 1 FLPIS(0.423)S(0.289)T(0.289)PQPER 85.536 0.0096125 4778100.0 19653.0 23996.0 31718.0 27551.0 30418.0 22149.0 24957.0 22951.0 23566.0 19617.0 True False 22979.8647355565 26378.16429596073 32474.277411184867 26007.406791547146 24457.81125744005 20987.46744891393 22592.89228696704 22348.560568594596 23910.60816750813 23173.40681191344 0.9916480956845137 1.1382946197794157 1.4013596565564048 1.122295353576443 1.0554257928474418 0.9056703496062686 0.9749491074118649 0.9644054821108655 1.031812385704794 1.0 14.500182535506573 -6.343139138089956 2.9047658495719664 0.9744507894880235 1.181593372170539 0.43981423705658795 0.0992357943358411 0.2507713672615311 4.130796480937937 0.03413644810265807 0.04041412904959725 4.537962073585864e-07 6.343139138089956 0.2071425826825154 FLPISS(ph)TPQPERR ddPTM_PC-9_AZD4547_30min_R2 1 FLPISSTPQPERR 13 1 J3KNG6;Q08AE8-3;Q08AE8-5;Q08AE8-2;Q08AE8;Q08AE8-4 J3KNG6 SPIRE1 Protein spire homolog 1 1 FLPIS(0.077)S(0.504)T(0.419)PQPERR 65.472 0.018186 5307000.0 11821.0 7779.2 14173.0 23564.0 20850.0 16469.0 17143.0 22126.0 17963.0 15987.0 True False 15579.832107925537 10293.674269452727 13985.05675952631 18131.683860170862 17955.337397197385 15439.190826531443 18668.693789608526 18706.93510489889 18912.487507808677 15427.29999606409 1.0098871553609745 0.6672375770276662 0.9065135677075227 1.1752985852869091 1.1638677799600878 1.0007707654917184 1.2101076529510284 1.212586460992625 1.225910399916625 1.0 13.913197970742956 -5.670230851126686 4.491016930555685 1.1480528163597434 0.8280510218581641 0.5827739235009242 0.10900463182487041 0.1324239087969723 4.729996082492919 0.02921732292179737 0.05172698007124706 2.136825948412741e-06 5.670230851126686 -0.3200017945015793 FLPISS(ph)TPQPERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FLPISSTPQPERR 13 1 J3KNG6;Q08AE8-3;Q08AE8-5;Q08AE8-2;Q08AE8;Q08AE8-4 J3KNG6 SPIRE1 Protein spire homolog 1 1 FLPIS(0.303)S(0.527)T(0.17)PQPERR 93.478 0.010121999999999999 0.0 12455.0 9507.3 13877.0 15420.0 16349.0 14790.0 13830.0 13603.0 14426.0 9567.1 True False 14563.385502536823 10451.121912443214 14207.880308815566 14556.067392314515 13145.5308122785 14014.386363693025 12519.92227947086 13245.93566356988 14636.952958689311 11301.53949687807 1.2886196174034346 0.9247520583660506 1.2571632663621042 1.2879720852486933 1.1631628430719385 1.240042240932251 1.1078067977313495 1.1720470177738997 1.2951291249066212 1.0 13.464231689643938 -10.04809846580094 15.170327047103248 0.9999998889277434 1.187147984259762 0.2229009531365974 0.10759731990958071 0.0 0.0 0.10178459527749993 0.024686390434698637 8.951617861915619e-11 10.04809846580094 0.1871480953320187 FLPISST(ph)PQPER ddPTM_PC-9_AZD4547_30min_R2 1 FLPISSTPQPER 12 0 J3KNG6;Q08AE8-3;Q08AE8-5;Q08AE8-2;Q08AE8;Q08AE8-4 J3KNG6 SPIRE1 Protein spire homolog 1 1 FLPIS(0.174)S(0.174)T(0.652)PQPER 107.09 0.0038950000000000005 6791600.0 50631.0 51887.0 81620.0 97492.0 87371.0 90783.0 73551.0 104940.0 75562.0 92744.0 True False 66730.60480977736 68658.45804441247 80537.66547043946 75016.72563638505 75241.04478323908 85106.32465875296 80096.89651283287 88723.93428130221 79556.05305711964 89497.06078907655 0.7456178361772756 0.7671588031949368 0.8998917367828171 0.8382032323182296 0.8407096738133609 0.9509398845994337 0.8949667822231877 0.991361431303354 0.8889236401250593 1.0 16.44955268254475 -2.2134558699942604 0.21395113367309732 0.9927610166681841 3.3558331571189705e-13 0.732785728370668 0.042180784569046524 19.34588112171601 0.3149060836111941 0.06860594026772734 6.182784529980756 0.006117079573345429 2.2134558699942604 -0.9927610166678484 FLPISST(ph)PQPER ddPTM_PC-9_Lapatinib_30min_R1 2 FLPISSTPQPER 12 0 J3KNG6;Q08AE8-3;Q08AE8-5;Q08AE8-2;Q08AE8;Q08AE8-4 J3KNG6 SPIRE1 Protein spire homolog 1 1 FLPIS(0.15)S(0.15)T(0.699)PQPER;FLPIS(0.12)S(0.12)T(0.76)PQPER 102.73 0.0056635 15382700.0 97742.0 82110.0 93189.0 87384.0 104699.0 78129.0 72896.0 79164.0 95574.0 64591.0 True False 96348.1811563123 81919.87933982354 85527.36013994266 93810.51086447877 98540.81066615373 74787.6047975944 76670.19819713272 82842.24844239061 84809.44968116253 75755.46828790245 1.2718313718311256 1.081372489554071 1.1289925608393434 1.2383331921064709 1.3007748865290814 0.9872238465132344 1.0120747707050521 1.0935481004164007 1.1195158791554316 1.0 16.209062410539026 -6.77266127537482 24.999998898406105 1.046419412633831 1.1951451062260752 0.5619465204406503 0.0711524451514349 193.86567843805446 431888.99059478776 0.026718062193204238 0.023769833220473557 1.6878689524950526e-07 6.77266127537482 0.14872569359224408 FLPLFDR ddPTM_PC-9_AZD4547_30min_R2 2 FLPLFDR 7 0 P61604;B8ZZL8;S4R3N1 P61604 HSPE1;HSPE1-MOB4 10 kDa heat shock protein, mitochondrial 0 ; 128.82 0.020505000000000002 17882800.0 34544.0 31258.0 46112.0 65181.0 48978.0 42086.0 37972.0 52284.0 44119.0 42529.0 False True 45528.273440164085 41361.53721649443 45500.524750954464 50154.527486411345 42178.25012181935 39454.35576691982 41351.43443848886 44204.70916679625 46451.04026927637 41040.072654820106 1.109361423969527 1.0078329432888216 1.1086852875152131 1.2220867128635737 1.0277333199814784 0.9613617426743506 1.0075867746699076 1.077110889607659 1.1318459560236853 1.0 15.324745664555232 FLPLFDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FLPLFDR 7 0 P61604;B8ZZL8;S4R3N1 P61604 HSPE1;HSPE1-MOB4 10 kDa heat shock protein, mitochondrial 0 118.01 0.032758999999999996 7787900.0 24050.0 22896.0 30415.0 31402.0 31874.0 29617.0 24942.0 29658.0 24279.0 20038.0 False True 28121.189990847924 25168.96356560746 31140.208949529817 29642.647746657625 25628.51850942351 28063.832382251272 22579.313195557635 28879.50892524851 24634.034443644672 23670.73077927927 1.188015285758075 1.0632947415227123 1.315557565159295 1.2522911955302205 1.0827092221359738 1.1855921409413184 0.9538916819299456 1.220051429528693 1.0406959832946372 1.0 14.530816626195175 -6.652129626953039 1.82788822616426 1.0780053067291941 1.197843554068748 0.27236121524218126 0.09595107326142556 0.5258495683978854 3.610690678235682 0.03784235282479544 0.03749317970956627 2.227770111686502e-07 6.652129626953039 0.11983824733955384 FLPLFDR ddPTM_PC-9_Lapatinib_30min_R1 2 FLPLFDR 7 0 P61604;B8ZZL8;S4R3N1 P61604 HSPE1;HSPE1-MOB4 10 kDa heat shock protein, mitochondrial 0 ; 124.32 0.021391 19809700.0 34052.0 30667.0 32450.0 28621.0 28005.0 26043.0 25440.0 21974.0 28799.0 21688.0 False True 33566.41223562798 30595.99244567487 29782.086260622367 30725.88381685712 26357.8009599484 24929.201599198135 26757.15872112401 22994.992260030915 25555.35335308558 25436.74190255653 1.319603444663421 1.2028267048854953 1.1708294393484846 1.2079331517598566 1.03620978900994 0.9800469609943487 1.0519098249149108 0.9040069812447087 1.0046629969743541 1.0 14.634626272575705 -6.133043316329609 0.8925152597655605 0.971161493001808 1.271840579455449 0.841940413857627 0.04905576495181392 0.2340165032957998 0.389326485850149 0.023259824733867035 0.04456147827476412 7.361336722030478e-07 6.133043316329609 0.30067908645364105 FLPLNIRNS(ph)PFTR ddPTM_PC-9_AZD4547_30min_R2 2 FLPLNIRNSPFTR 13 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;H3BSK8 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 FLPLNIRNS(0.624)PFT(0.376)R;FLPLNIRNS(0.996)PFT(0.004)R 109.39 0.00037383 23536000.0 49522.0 34414.8 68518.0 121956.0 91564.0 72749.0 46461.0 67890.0 50815.0 64748.0 True False 65268.96587841031 45538.71108190579 67609.40655113403 93840.9284014174 78851.91910968743 68199.99352962138 50595.93899311681 57399.16045700024 53500.97715912141 62481.1922277574 1.0446178049946755 0.7288387026276225 1.0820761278799416 1.5019068147635055 1.262010475444438 1.0915283639437885 0.8097787060253864 0.9186630153881817 0.856273308039623 1.0 15.931134361913191 -7.170050342436139 5.987195659670716 0.8901484016269609 1.1252294857004856 0.2551264334995723 0.1862905465606743 0.3755368045097539 19.973516502104395 0.08194831284040364 0.06314867711422284 6.760046099214568e-08 7.170050342436139 0.2350810840735248 FLPLNIRNS(ph)PFTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FLPLNIRNSPFTR 13 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;H3BSK8 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 FLPLNIRNS(0.999)PFT(0.001)R;FLPLNIRNS(0.998)PFT(0.002)R 85.67200000000001 0.0037628999999999996 17097200.0 26360.0 18488.4 21171.3 30557.0 40060.0 33000.0 27801.0 30285.0 30047.0 20734.3 True False 30822.22736626825 20323.806166421098 21676.104084602375 28844.990357130642 32210.530573116204 31269.421906820164 25167.48801819014 29490.05083960993 30486.38053166075 24493.26445737151 1.2583960549608146 0.829771229628986 0.884982241641486 1.1776703104370978 1.3150770747270522 1.2766539128029255 1.027526896710402 1.2040065500837958 1.2446842512446536 1.0 14.580097448371665 -5.8016283303733385 11.367173551484292 1.190118346046269 0.9749888788505677 0.2649181404630757 0.14089584324641455 0.7464528783565714 208.89049407225073 0.039432648675506665 0.05866376918599671 1.5789619687922021e-06 5.8016283303733385 -0.21512946719570125 FLPLNIRNS(ph)PFTR ddPTM_PC-9_Lapatinib_30min_R1 1 FLPLNIRNSPFTR 13 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;H3BSK8 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 FLPLNIRNS(0.997)PFT(0.003)R 61.657 0.024798 8676000.0 22951.0 9476.1 20890.0 14273.0 11558.0 16427.0 12367.0 5814.6 16684.0 10998.0 True False 22623.714531302074 9454.158672659847 19172.504837731954 15322.684033332218 10878.1811639023 15724.455503207308 13007.302747804259 6084.767543240915 14804.872229691293 12898.989646086166 1.7539136902995036 0.7329379224308816 1.486357099569369 1.187898002382028 0.8433359094293852 1.2190455171020662 1.0083970221459133 0.4717243528517108 1.1477544083604574 1.0 13.654970445999036 -1.5228787452803463 0.3564935684095539 0.9002522039485105 8.008778558598474 0.27339731611740137 0.2968267682160882 90.33643274702376 1.2649374372348114 0.2416678366848582 434.3111000438551 0.0299999999999994 1.5228787452803463 7.108526354649963 FLPLNIRNSPFT(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FLPLNIRNSPFTR 13 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;H3BSK8 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 FLPLNIRNS(0.017)PFT(0.983)R 93.598 0.041647 2743400.0 11059.0 9561.2 11780.0 16752.0 18790.0 20878.0 14552.0 15850.0 14476.0 12924.0 True False 12931.070274793645 10510.372748230524 12060.879875898785 15813.439750716787 15108.234385143616 19783.120926381547 13173.52921264352 15433.954294463181 14687.684114098616 15267.018893672288 0.8469937952427096 0.6884364800640125 0.7899957391745713 1.0357909334395974 0.9895995079566919 1.2958077188586599 0.8628750186523673 1.0109343809654996 0.9620531825100584 1.0 13.898130762104161 -5.734424729249958 5.5802348326084505 1.0267803662939101 0.7626853099939579 0.5190238784054293 0.10900842104973335 0.13564242847659266 11.761885927292726 0.030116284812681162 0.051005207257348514 1.8432119218146267e-06 5.734424729249958 -0.2640950562999522 FLPS(ph)PVVIKK ddPTM_PC-9_AZD4547_30min_R2 1 FLPSPVVIKK 10 1 Q13618-3;Q13618-2;Q13618;H7C399;A0A087WTG3 Q13618-3 CUL3 Cullin-3 1 FLPS(1)PVVIKK 82.505 0.0218 0.0 42795.0 35465.0 52185.0 70123.0 59273.0 49948.0 40562.0 53884.0 34873.0 49919.0 True False 56402.91980870258 46928.367694125496 51492.99280292671 53957.22573955024 51043.96707645471 46824.74366407143 44171.939420994015 45557.465931138584 36716.31558535947 48171.351004161086 1.1708810036037902 0.9741966275779099 1.0689547153966825 1.1201102857773153 1.0596332885088793 0.9720454728377177 0.9169753079414028 0.9457377669811106 0.7622023219192645 1.0 15.555887765580865 -6.979692144749723 1.819679836140706 0.8966040716522353 1.0774126366406738 0.559948148034265 0.07259566874212035 0.2634971301057208 1.7634915926832164 0.03215471751063934 0.024981836774987748 1.0478710817869258e-07 6.979692144749723 0.18080856498843845 FLPS(ph)PVVIKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FLPSPVVIKK 10 1 Q13618-3;Q13618-2;Q13618;H7C399;A0A087WTG3 Q13618-3 CUL3 Cullin-3 1 FLPS(1)PVVIKK 93.839 0.009997399999999998 0.0 42475.0 34659.0 37621.0 41049.0 50222.0 42719.0 38938.0 44945.0 41100.0 36480.0 True False 49665.178580509986 38099.71646664876 38518.02731843703 38749.15761265362 40381.35962164354 40478.74043749847 35249.51075329257 43765.241373163844 41701.0097464391 43093.53522447892 1.1524971975912086 0.884116753665792 0.8938237978804113 0.8991872542088978 0.9370630515991004 0.9393228062316146 0.8179767700578295 1.0155871674297765 0.9676859772402984 1.0 15.395183835890903 FLRPHYGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FLRPHYGK 8 1 Q13200;C9JPC0;H7C2Q3 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 0 67.98100000000001 0.020205 8830000.0 37046.0 39271.0 51455.0 47974.0 51886.0 51613.0 55296.0 51473.0 48901.0 41196.0 False True 43317.156108147676 43169.56534700258 52681.882344174155 45286.17231380652 41719.31076676753 48906.32342050632 50057.962571628384 50121.8882901516 49616.08461339708 48664.5086926434 0.890118019720107 0.8870851983661043 1.082552434196013 0.9305790509429805 0.8572841252802831 1.0049690161137796 1.0286338836334668 1.0299474840424827 1.0195537969316337 1.0 15.57058236951721 -6.974303606201946 24.544061991547363 1.021282579583769 0.935266269909357 0.3666897793223677 0.057219960124888586 220.30120789050747 210421.07181317444 0.021256826159264157 0.01874617518934339 1.0609536073795005e-07 6.974303606201946 -0.08601630967441198 FLS(ph)LEYSPAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FLSLEYSPAGK 11 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 FLS(1)LEYSPAGK 128.08 0.0003279 2014200.0 12202.0 8292.3 9155.7 12263.0 14840.0 15770.0 13865.0 17196.0 13812.0 11854.0 True False 14267.557599514601 9115.504742098476 9374.006611185605 11575.943867182421 11932.208529831361 14942.993438501626 12551.606826092811 16744.623220668065 14013.974370263188 14003.036363787636 1.0188902769981392 0.6509662979717388 0.6694267134396029 0.8266738417617935 0.8521157997338697 1.06712523272058 0.8963489417589263 1.1957851701342626 1.0007811167657779 1.0 13.77345206900641 -6.588867717636157 2.0375368739264745 1.0406263571408754 0.7697588202932676 0.4790786534560092 0.11846441679575316 0.2651467390589632 2.238417335730498 0.04404007943323591 0.045521531085586965 2.577106001790608e-07 6.588867717636157 -0.2708675368476078 FLS(ph)PEFIPR ddPTM_PC-9_Lapatinib_30min_R1 1 FLSPEFIPR 9 0 A0A0A0MRF4;P49406 A0A0A0MRF4 MRPL19 39S ribosomal protein L19, mitochondrial 1 FLS(1)PEFIPR 93.667 0.012014 0.0 4887.8 5265.7 5737.4 3145.8 3985.8 5901.5 4525.0 3898.6 5375.6 3147.4 True False 4818.099075687262 5253.507595173644 5265.693119004465 3377.1526260811665 3751.3630803843043 5649.106602068417 4759.282359004959 4079.743188539029 4770.143320422471 3691.423896353118 1.305214250914728 1.4231656246154123 1.4264666607935819 0.914864486145189 1.0162374156190521 1.5303326739715153 1.2892809096529974 1.1051949879203915 1.2922231242895341 1.0 11.8499617003957 -14.522878745280336 0.11516569038314749 0.2457485341241222 1.3771295802780277 0.15585858591296975 0.18205483290774288 351.5915753911057 2.6479823587215403 63.26387568371876 2.1645896528976185 3.0000000000000132e-15 14.522878745280336 1.1313810461539056 FLSHS(ph)TDSLNK ddPTM_PC-9_AZD4547_30min_R2 4 FLSHSTDSLNK 11 0 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36 Q12802-2 AKAP13 A-kinase anchor protein 13 1 FLS(0.007)HS(0.848)T(0.144)DS(0.001)LNK;FLSHS(0.912)T(0.088)DSLNK;FLSHS(0.951)T(0.036)DS(0.013)LNK;FLS(0.005)HS(0.84)T(0.155)DSLNK 118.76 0.0010321 68206900.0 159158.0 158299.0 367813.0 548397.0 508719.0 452597.0 301253.0 471264.0 384733.0 401857.0 True False 209766.9333079444 209466.05604433568 362935.55929525493 421972.5442991902 438092.14797913085 424296.03804211953 328063.9333956089 398440.9773693873 405069.20093201345 387788.10874575126 0.5409318351364808 0.5401559545542167 0.93591203832712 1.088152356357713 1.1297204274676738 1.0941440144063423 0.8459876050781645 1.0274708491142013 1.044563233880883 1.0 18.564909039313797 -5.318660963995498 3.5062264393892635 1.0317804944502533 0.5293197101954289 0.8753014943340646 0.07318622784591844 0.0772153875955684 1.8958402403516883 0.021420450569714446 0.05340551016813768 4.8010810321063216e-06 5.318660963995498 -0.5024607842548244 FLSHS(ph)TDSLNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 FLSHSTDSLNK 11 0 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36 Q12802-2 AKAP13 A-kinase anchor protein 13 1 FLS(0.023)HS(0.956)T(0.02)DSLNK;FLS(0.003)HS(0.757)T(0.24)DSLNK;FLS(0.001)HS(0.952)T(0.032)DS(0.015)LNK;FLS(0.001)HS(0.972)T(0.027)DSLNK;FLS(0.005)HS(0.756)T(0.239)DSLNK 131.32 9.326299999999999e-05 46486100.0 155258.0 194239.0 294640.0 364863.0 388103.0 363593.0 363019.0 320903.0 330601.0 265829.0 True False 181540.1129147218 213521.76423916928 301665.3350284232 344420.9090118053 312057.0031706974 344525.54301110504 328631.21229003783 312479.6362748332 335435.414189356 314021.6933987934 0.5781132855817513 0.6799586421184165 0.9606512587183643 1.0968061005084966 0.9937434569986828 1.0971393067853217 1.0465239160171365 0.9950893293158511 1.0681918518392552 1.0 18.260504701954346 -5.245452404707725 2.5225332180651217 1.043236260233708 0.5873141753589518 0.9508402095967828 0.03738097417571824 0.053796882239770076 0.6521137976659009 0.009751908004377655 0.03317374607092606 5.682606650899169e-06 5.245452404707725 -0.45592208487475616 FLSHS(ph)TDSLNK ddPTM_PC-9_Lapatinib_30min_R1 4 FLSHSTDSLNK 11 0 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36 Q12802-2 AKAP13 A-kinase anchor protein 13 1 FLSHS(0.872)T(0.128)DSLNK;FLS(0.016)HS(0.862)T(0.122)DSLNK;FLSHS(0.957)T(0.043)DSLNK;FLS(0.018)HS(0.93)T(0.052)DSLNK 111.72 0.0010072000000000002 62996000.0 426218.0 264179.0 501554.0 327253.0 426892.0 482939.0 321747.0 369481.0 524468.0 269042.0 True False 420140.05316119065 263567.3097566098 460318.16617442894 351320.2773040056 401783.05186196393 462284.82475579425 338405.4853398378 386648.4361167051 465396.8909471192 315545.551224069 1.3314719587437602 0.835274998282104 1.4588010015947173 1.1133742052174678 1.27329651869076 1.465033567934937 1.072445749994225 1.2253331876073448 1.4748960622063747 1.0 18.267488757874496 -6.291918525558393 23.20658603709286 1.2647914065579178 1.1793458646768662 0.022697444885286577 0.20419502181030663 1128.8849911705204 859519.4837077683 0.061085497657391866 0.0692774134550456 5.1060078063406e-07 6.291918525558393 -0.08544554188105158 FLTVLCSR ddPTM_PC-9_Lapatinib_30min_R1 1 FLTVLCSR 8 0 P09525-2;P09525;Q6P452 P09525-2 ANXA4 Annexin A4;Annexin 0 110.12 0.017357 2970900.0 11713.0 8823.1 14572.0 12630.0 10461.0 11459.0 10133.0 12475.0 10649.0 12370.0 False True 11545.970472098867 8802.670654039648 13373.946409546668 13558.852332444898 9845.704547117308 10968.925282233678 10657.63715885021 13054.634042226533 9449.597481058661 14508.138018011075 0.7958271735328933 0.6067402062974314 0.9218237649065394 0.9345687444944561 0.6786332288054052 0.7560532763485118 0.7345971719885298 0.8998145748282725 0.6513308233852954 1.0 13.824574754601725 -11.628759569770379 2.1711644125791287 1.375970049173874 0.7785411095193746 0.27732578290853893 0.10862642101581352 10259796.240280462 2752221.4966083104 19032601.88765727 0.028097783970201292 2.3509339637013557e-12 11.628759569770379 -0.5974289396544994 FLVHNVK ddPTM_PC-9_AZD4547_30min_R2 2 FLVHNVK 7 0 D3YTB1;F8W727;P62910 D3YTB1 RPL32 60S ribosomal protein L32 0 ; 103.29 0.0089006 6428100.0 118169.0 106290.0 147799.0 192107.0 171403.0 151229.0 145484.0 163161.0 138334.0 148711.0 False True 155744.28393210843 140646.16388576326 145839.08868984913 147819.69917356325 147606.6520811423 141772.62672326964 158431.79416014728 137948.21651678588 145646.05282554182 143504.67315410575 1.0852906773625337 0.9800807234669437 1.0162671743326193 1.0300688885220044 1.0285842881411362 0.9879303830825348 1.1040183617575416 0.9612803087509705 1.0149220204775944 1.0 17.130738192706964 -7.550706710110148 0.0038943285475712083 4.392110016951476e-07 2.033820484644885 0.058521235990778075 0.041165850222271046 30242.139186782853 94.26092083831553 24524.570120639048 24697.631539850703 2.813800418473007e-08 7.550706710110148 2.0338200454338833 FLVHNVK ddPTM_PC-9_Lapatinib_30min_R1 2 FLVHNVK 7 0 D3YTB1;F8W727;P62910 D3YTB1 RPL32 60S ribosomal protein L32 0 ; 83.801 0.017194 14948500.0 206775.0 194017.0 207508.0 200407.0 189335.0 195522.0 195763.0 170643.0 185376.0 170859.0 False True 203826.35058210947 193567.7655568686 190447.49324404364 215145.5993181536 178198.6875469321 187159.9798440433 205898.65026428452 178571.69674289913 164497.00278417955 200391.75049469306 1.0171394285390374 0.9659467771453737 0.9503759150459002 1.0736250309059068 0.8892516139363298 0.9339704822280088 1.027480671015633 0.8911130138943929 0.8208771188339706 1.0 17.61246359292319 -6.947693644197303 0.8086618060952269 0.9120580951876793 0.9910423086792314 0.1489656165458041 0.06661896990943918 1.231857453118364 1.70071376441319 0.049001006688909644 0.038819709555589964 1.127992873391005e-07 6.947693644197303 0.07898421349155205 FLYES(ph)SSR ddPTM_PC-9_AZD4547_30min_R2 1 FLYESSSR 8 0 H0Y6U5;Q86XI2 H0Y6U5 NCAPG2 Condensin-2 complex subunit G2 1 FLY(0.015)ES(0.732)S(0.127)S(0.127)R 60.972 0.03837 6655200.0 27613.0 23448.0 12972.0 11613.0 15999.0 12431.0 17817.0 9898.9 17411.0 17536.0 True False 36393.35961391999 31027.107449368497 12799.982804245765 8935.802269061456 13777.81501284226 11653.6876048705 19402.678483897504 8369.252459092639 18331.309914739017 16922.069977542993 2.1506446706707294 1.8335290830580462 0.7564076275084796 0.5280560995741074 0.8141920599032256 0.6886679714914263 1.1465901340466318 0.49457616415718286 1.083278224180978 1.0 14.046618435222292 -5.191179888079397 3.8380154499757264 0.7902605309465459 2.07634683489153 0.835757481827291 0.21025410620650228 0.07808303845206654 2.2328994762310717 0.052376619126106604 0.15650107491019052 6.439025009550254e-06 5.191179888079397 1.2860863039449844 up FLYES(ph)SSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FLYESSSR 8 0 H0Y6U5;Q86XI2 H0Y6U5 NCAPG2 Condensin-2 complex subunit G2 1 FLY(0.104)ES(0.687)S(0.104)S(0.104)R 66.79899999999999 0.027241 5784200.0 8546.7 11101.0 8031.1 6821.7 13142.0 11751.0 7249.1 12465.0 11268.0 13604.0 True False 9993.487504980458 12203.033916046848 8222.591882116356 6439.502265249805 10566.919440636373 11134.756873546778 6562.4127690608975 12137.806957759205 11432.773183038344 16070.29751079525 0.6218607650709214 0.7593533291993779 0.5116639487596801 0.400708341642341 0.6575434856472337 0.6928780793303289 0.40835664458934784 0.7552944772556708 0.7114226214765693 1.0 13.97210901754664 -8.645390863255779 1.2001832165066337 0.9966043595046797 0.5865899137938333 0.5228740460112071 0.11796211957583376 0.5160789600279422 1.5539683259422827 0.11525544972485713 0.0356796351539198 2.26260705388484e-09 8.645390863255779 -0.41001444571084644 FMS(ph)SPSLSDLGK ddPTM_PC-9_AZD4547_30min_R2 1 FMSSPSLSDLGK 12 0 B1AHC3;B1AHC4;F8WEZ7;E9PH80;P85299;P85299-5 B1AHC3;P85299 PRR5-ARHGAP8;PRR5 Proline-rich protein 5 1 FMS(0.847)S(0.135)PS(0.015)LS(0.003)DLGK 74.46 0.020811 6442900.0 23066.0 25659.0 31675.0 39237.0 40251.0 47430.0 43539.0 45950.0 40139.0 37804.0 True False 30400.50819739534 33952.76996090695 31254.96880392267 30191.515855607016 34662.843432834154 44464.194602124386 47413.88665378085 38849.48332595608 42260.665594607395 36480.49346664207 0.8333359916086033 0.9307102710097254 0.8567583887674755 0.8276071123657984 0.9501747410442795 1.2188484961910577 1.2997051889425872 1.0649385365765467 1.1584455575758794 1.0 15.154837624322452 -6.626229964276503 4.477670301369814 1.1609315680010328 0.8688172314261386 0.7384076125111911 0.0809278031775901 0.10837291737534782 3.796034746485728 0.02753029515604356 0.027479301925481096 2.3646672454932887e-07 6.626229964276503 -0.29211433657489416 FMS(ph)SPSLSDLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FMSSPSLSDLGK 12 0 B1AHC3;B1AHC4;F8WEZ7;E9PH80;P85299;P85299-5 B1AHC3;P85299 PRR5-ARHGAP8;PRR5 Proline-rich protein 5 1 FMS(0.99)S(0.009)PS(0.001)LSDLGK;FMS(0.495)S(0.495)PS(0.007)LS(0.002)DLGK 91.914 0.007237 10389000.0 83124.0 92159.0 107815.0 132348.0 131100.0 118147.0 133605.0 106544.0 103673.0 80134.6 True False 97195.25142616405 101307.93646238734 110385.71849066445 124932.97063800505 105411.8961092243 111951.1633340932 120948.96718356515 103747.33289269937 105189.02149495327 94662.3686348554 1.0267570189488795 1.0702028474817287 1.1660992650253588 1.3197743986305006 1.1135565022235334 1.1826364050315126 1.2776879442992388 1.0959722896105393 1.1112020860232508 1.0 16.530503401087024 -10.538197047873858 14.371435860960014 0.9999999339478067 1.156399880121354 0.21668189534151272 0.08599508725609317 0.0 0.0 0.08758947406361402 0.02124356783862231 2.896029304606694e-11 10.538197047873858 0.15639994617354724 FMS(ph)SPSLSDLGK ddPTM_PC-9_Lapatinib_30min_R1 2 FMSSPSLSDLGK 12 0 B1AHC3;B1AHC4;F8WEZ7;E9PH80;P85299;P85299-5 B1AHC3;P85299 PRR5-ARHGAP8;PRR5 Proline-rich protein 5 1 FMS(0.496)S(0.496)PS(0.007)LSDLGK;FMS(0.887)S(0.102)PS(0.011)LSDLGK 137.84 6.2816e-05 9607700.0 51918.0 61413.0 61605.0 60725.0 59496.0 65777.0 59936.0 62428.0 65849.0 50114.0 True False 51177.639799404846 61270.801971703484 56540.07470217694 65190.91907266162 55996.56225363655 62963.87104367614 63039.19281089964 65328.6327846187 58432.39219928934 58776.138127292426 0.8707213748642112 1.0424434800225957 0.9619562717735417 1.1091392042715804 0.9527091101556195 1.0712488613544884 1.07253036384212 1.1114822250338297 0.9941516074557564 1.0 15.84294294970513 -3.9953140148363233 1.3659697588738298 1.0428064823794132 1.485563890173957e-17 0.43183706106882846 0.055099835154974 8.662546655220396 2.927717740169545 0.015122947052372058 20.97391435269626 0.00010108483002628902 3.9953140148363233 -1.0428064823794132 FMS(ph)SPVLSDLPR ddPTM_PC-9_Lapatinib_30min_R1 1 FMSSPVLSDLPR 12 0 E9PJV4;E9PLJ6;E9PL62;E9PP25;E9PS02;E9PP62;E9PIU0;Q6MZQ0-4;Q6MZQ0 E9PJV4 PRR5L Proline-rich protein 5-like 1 FMS(0.835)S(0.164)PVLSDLPR 83.226 0.009910200000000001 1313800.0 15974.0 11653.0 17401.0 12315.0 12522.0 14079.0 12247.0 12981.0 15111.0 11621.0 True False 15746.207830727177 11626.01819445818 15970.356949802464 13220.686181635698 11785.48057919922 13476.873989751974 12881.089734968766 13584.144649470347 13409.04005411563 13629.674365990848 1.1552886303738528 0.8529931003683956 1.1717342998048548 0.9699928132270226 0.864692747803769 0.9887891396275654 0.9450768513670457 0.99665951545885 0.983812209598657 1.0 13.734463473887574 -4.731530313278582 24.838398536470777 0.9768186789881997 1.1552898071200297 0.30064280173273505 0.08250725846026907 4589.238831892881 3810970.476861799 0.020064263671917246 2.4557380247004494 1.8555372904454275e-05 4.731530313278582 0.17847112813182997 FMSSPS(ph)LSDLGK ddPTM_PC-9_AZD4547_30min_R2 1 FMSSPSLSDLGK 12 0 B1AHC3;B1AHC4;F8WEZ7;E9PH80;P85299;P85299-5 B1AHC3;P85299 PRR5-ARHGAP8;PRR5 Proline-rich protein 5 1 FMS(0.232)S(0.232)PS(0.451)LS(0.084)DLGK 132.59 8.2761e-05 4975500.0 15023.0 18657.0 21895.0 32805.0 33218.0 30250.0 25111.0 35065.0 28434.0 28708.0 True False 19800.001502188075 24687.510392479886 21604.657994061137 25242.314082197634 28606.254084417415 28358.462717989933 27345.83035354718 29646.509963539713 29936.96319083849 27702.94165803515 0.7147255965304734 0.8911512249212478 0.7798687323804393 0.9111781121943121 1.0326070941321952 1.0236625073267138 0.9871092641028469 1.0701574702605936 1.080642032906833 1.0 14.757751557633647 -6.045050240126581 2.450390596617287 1.034584132053411 0.8030971471716903 0.8260908317897323 0.04879244330650955 0.11511017336208887 1.3738907118266774 0.014968985298815761 0.02208220593080389 9.014668479358172e-07 6.045050240126581 -0.2314869848817207 FMSSPS(ph)LSDLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FMSSPSLSDLGK 12 0 B1AHC3;B1AHC4;F8WEZ7;E9PH80;P85299;P85299-5 B1AHC3;P85299 PRR5-ARHGAP8;PRR5 Proline-rich protein 5 1 FMS(0.013)S(0.103)PS(0.863)LS(0.02)DLGK 112.64 0.00081788 10175000.0 85981.0 89159.0 110040.0 120430.0 143060.0 107490.0 125870.0 121970.0 125740.0 102190.0 True False 100535.88509784175 98010.11628869652 112663.7709290237 113682.6975393277 115028.41996480279 101853.03517466954 113946.68238011566 118768.41673789707 127578.70962329075 120716.23806440485 0.8328281821059034 0.8119049919067715 0.9332942505126363 0.9417349261552982 0.9528827422822148 0.843739308048422 0.9439217474563987 0.9838644629940458 1.056847957399274 1.0 16.881260226746107 -1.5228787452858203 0.1825228090444451 1.0314798046322935 0.09760828423869004 0.5951650381627026 0.04743807901417377 43.04131464719236 0.489649080251214 0.1140896773915301 11.190138415583728 0.029999999999621264 1.5228787452858203 -0.9338715203936034 FNADEFEDMVAEK ddPTM_PC-9_Lapatinib_30min_R1 1 FNADEFEDMVAEK 13 0 F8W7C6;A0A087WV22;X1WI28;P27635 F8W7C6 RPL10 60S ribosomal protein L10 0 119.87 0.0015508 0.0 7973.5 8420.6 7934.7 7380.6 7395.9 8466.4 7039.7 6914.2 7364.5 7002.0 False True 7859.796427839183 8401.102618060122 7282.339594827745 7923.393944959845 6960.887702898855 8104.31180814235 7404.181220483354 7235.4589735280715 6535.0324583769825 8212.28637042147 0.9570777336927917 1.0229919219961348 0.8867615261271022 0.9648219250485295 0.8476187250325525 0.9868520704942758 0.9015980308664464 0.8810529305929128 0.79576285623873 1.0 13.003568221166498 -5.267100881024487 24.857588585524102 0.9062624229152623 0.9900348290973428 0.22209587013564736 0.06129419248404403 549.6898563745461 2413496.7504415847 0.015514083610597362 0.03383637179701649 5.406287272564543e-06 5.267100881024487 0.08377240618208048 FNADEFEDMVAEKR ddPTM_PC-9_AZD4547_30min_R2 2 FNADEFEDMVAEKR 14 1 F8W7C6;A0A087WV22;X1WI28;P27635 F8W7C6 RPL10 60S ribosomal protein L10 0 ; 123.68 2.5614000000000002e-05 7559800.0 16026.5 11580.8 18031.5 31321.0 24141.0 20851.8 17638.5 23271.7 13983.8 24759.3 False True 21122.59362809143 15324.06712511288 17792.390528427204 24100.427354626187 20789.438853992422 19547.93364968538 19208.29232969783 19675.593495465775 14722.955119506489 23892.48444314438 0.8840685311883614 0.6413760428129068 0.7446856592401166 1.0087032770483386 0.8701246161094672 0.8181624517200173 0.803947047675462 0.8235055480432222 0.6162170013981546 1.0 14.544269258770324 -5.610254767541987 19.536551677060004 0.8419680681543685 0.7448180568384511 0.11049115563472622 0.1170381067200658 8.642041551256195 1924.2154896557138 0.03156248060193181 0.05466786268207249 2.453269346942692e-06 5.610254767541987 -0.09715001131591738 FNADEFEDMVAEKR ddPTM_PC-9_Lapatinib_30min_R1 3 FNADEFEDMVAEKR 14 1 F8W7C6;A0A087WV22;X1WI28;P27635 F8W7C6 RPL10 60S ribosomal protein L10 0 ;; 110.25 0.00032434 1678900.0 23064.0 17894.7 21868.9 19508.4 17754.4 21558.5 15077.2 18851.3 20872.300000000003 16576.4 False True 22735.1031305804 17853.265921597093 20070.923458395224 20943.112814114662 16710.12109849342 20636.493210318058 15857.823642693811 19727.200218054106 18521.44177893706 19441.60865333538 1.1694044220296549 0.9183018874589992 1.0323694821905531 1.07723147747456 0.8595030070017714 1.0614601691808916 0.8156641729321745 1.0146897085426996 0.952670229567631 1.0 14.246859976074019 -6.237816180061271 24.888319090088622 0.9501887808946512 1.0387566556555667 0.22605787029087177 0.08857149306336518 1238.7419615506901 1305081.8718527863 0.024695784768388553 0.031864986188489076 5.783407847363916e-07 6.237816180061271 0.08856787476091554 FNAHGDANTIVCNSK ddPTM_PC-9_AZD4547_30min_R2 2 FNAHGDANTIVCNSK 15 0 P09382 P09382 LGALS1 Galectin-1 0 ; 186.42 3.1321e-07 29974000.0 185240.0 187642.0 229900.0 344540.0 292800.0 276390.0 218433.0 275600.0 221661.0 252089.0 False True 244142.46676864306 248293.60696069617 226851.37578600858 265111.62608993653 252149.7740958944 259107.28960744635 237873.11383920908 233012.3526579647 233377.54793009988 243263.44083992 1.0036134732193545 1.020677854853193 0.9325337790288373 1.0898128595673107 1.0365296701604334 1.0651304146353517 0.9778416066873854 0.9578601365393781 0.9593613702260936 1.0 17.89215999371818 -7.4391599598678155 8.453860606285204 0.9687290012329954 1.0237852531867027 0.2774723729440727 0.040198940033292385 0.4531138560629188 42.14937517483526 0.017432574359820593 0.011708367820820315 3.637810231832352e-08 7.4391599598678155 0.055056251953707225 FNAHGDANTIVCNSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FNAHGDANTIVCNSK 15 0 P09382 P09382 LGALS1 Galectin-1 0 ; 144.4 3.9968e-05 21587000.0 154526.0 153644.0 166646.0 200976.0 216919.0 185542.0 185800.0 164754.0 168087.0 139624.0 False True 180684.19977238096 168896.7609221787 170619.47264847442 189715.96629298356 174415.27911607033 175811.85089197636 168199.67892448933 160429.3820712922 170544.95438563754 164936.7259370243 1.0954758483648408 1.0240094191433533 1.0344541015905693 1.1502348262049313 1.0574678145525036 1.065935132961863 1.0197830590423558 0.9726722848405934 1.034002302499654 1.0 17.331553149305904 -7.322324065273998 3.2271106834403738 1.0015137334533872 1.071040877834001 0.44928345192405195 0.035418786858849756 0.2509569761011067 5.196051557922485 0.016515895257967077 0.01083664049270224 4.760756123871443e-08 7.322324065273998 0.0695271443806138 FNAHGDANTIVCNSK ddPTM_PC-9_Lapatinib_30min_R1 2 FNAHGDANTIVCNSK 15 0 P09382 P09382 LGALS1 Galectin-1 0 ; 158.65 1.4000999999999999e-05 34440000.0 253230.0 205478.0 265480.0 231830.0 253070.0 238070.0 257320.0 209550.0 238600.0 216590.0 False True 249618.89376330527 205002.22831553072 243653.25918243558 248879.5515622096 238184.9201547631 227888.30106827544 270642.7705235702 219286.45799988523 211726.35543061284 254027.2929119662 0.9826459625730505 0.807008672042869 0.9591617356914253 0.9797354792441908 0.9376351549646545 0.8971016399692561 1.0654082379146643 0.8632397546191208 0.8334787691651194 1.0 17.954623984164208 FNDEHIPDSPFVVPVASLSDDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FNDEHIPDSPFVVPVASLSDDAR 23 0 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 0 ; 132.48 8.8725e-07 5433200.0 30952.0 34176.0 35153.0 36076.0 40703.0 32175.0 36499.0 36271.0 32628.0 26970.9 False True 36191.562270134076 37568.76741868455 35991.18083849489 34054.778679970055 32727.539338930288 30487.686359149644 33041.55049012341 35318.92468230117 33105.12277388846 31860.510668473067 1.1359379216086047 1.1791640068048241 1.1296485863959878 1.0688710872945386 1.0272132697268777 0.9569114154004482 1.0370690800891342 1.1085486058216358 1.0390644116902676 1.0 14.959481770485782 -5.8058920091159765 2.3797033854273555 1.0310578923902285 1.1575087219950668 0.6803851230953979 0.037003163835333794 0.18499732701403002 2.136499369432391 0.01222483555448564 0.021834002065289872 1.563536380449107e-06 5.8058920091159765 0.12645082960483833 FNDEHIPDSPFVVPVASLSDDAR ddPTM_PC-9_Lapatinib_30min_R1 1 FNDEHIPDSPFVVPVASLSDDAR 23 0 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 0 95.344 8.1076e-06 2500800.0 7387.8 10143.0 10445.0 8901.6 11418.0 8977.1 6873.0 8726.0 10016.0 7995.4 False True 7282.448617243406 10119.514506684063 9586.252418865977 9556.253358867098 10746.415688651703 8593.170359642192 7228.85031015272 9131.44181582915 8887.892606844165 9377.394236799173 0.7765961879543583 1.0791392844477659 1.0222725180143535 1.019073435279711 1.1459916707436866 0.9163708107653727 0.7708804949017666 0.9737717733989635 0.9477998239602549 1.0 13.194971371164582 -6.952628524706657 24.99986786973223 0.9098836737404168 1.0156034721941096 0.13900212097674303 0.10544242041387872 202.0193766194653 106613.1592621559 0.0368740943769986 0.03251988428082128 1.1152480570324934e-07 6.952628524706657 0.10571979845369284 FNDEHIPESPYLVPVIAPSDDAR ddPTM_PC-9_AZD4547_30min_R2 1 FNDEHIPESPYLVPVIAPSDDAR 23 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7 O75369-2 FLNB Filamin-B 0 113.42 9.769e-08 5844500.0 14931.0 14741.0 19592.0 25028.0 22231.0 18275.0 14708.0 19361.0 15515.0 19939.0 False True 19678.74741590697 19505.739974033666 19332.19727881462 19258.18127874537 19144.609384992564 17132.26136103359 16016.98350682856 16369.20232151982 16335.091225499727 19240.941678959272 1.022753862272056 1.0137622315733101 1.0047427824156412 1.0008959852419776 0.9949933690578122 0.8904065947961577 0.8324428073259929 0.8507485025756399 0.8489756633565806 1.0 14.231891787925559 -6.77387278072551 3.6771119878942238 0.8693330172576463 1.0091637452233777 0.6560627939807586 0.04417419895195605 0.12286943126750571 3.560898330070099 0.014989612108587264 0.013871124330083839 1.6831670443781825e-07 6.77387278072551 0.13983072796573137 FNDEHIPESPYLVPVIAPSDDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FNDEHIPESPYLVPVIAPSDDAR 23 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7 O75369-2 FLNB Filamin-B 0 111.11 6.5485e-07 1657900.0 17153.0 17625.0 23852.0 25772.0 24102.0 22271.0 22429.0 18502.0 21488.0 16552.0 False True 20056.664112807248 19374.693520432902 24420.722139213736 24328.078393951346 19379.38611765468 21103.069554145204 20304.3627481021 18016.342104489446 21802.221348697916 19552.746574440083 1.0257722124331066 0.9908937062458562 1.2489663304457295 1.2442281856071165 0.9911337030771921 1.079289268840202 1.0384404395976037 0.9214225753859527 1.115046485448669 1.0 14.255083656698806 -6.302754486764678 24.997886589195563 1.023757474521892 1.1263888216219635 0.23969021480009733 0.09007120750294205 806.2025763199332 487794.6741875555 0.029929925353507043 0.03393786267239302 4.980185428254537e-07 6.302754486764678 0.10263134710007149 FNDEHIPESPYLVPVIAPSDDAR ddPTM_PC-9_Lapatinib_30min_R1 3 FNDEHIPESPYLVPVIAPSDDAR 23 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7 O75369-2 FLNB Filamin-B 0 ;; 154.66 2.1889e-07 25575100.0 138810.3 126651.0 174195.4 138358.1 148026.3 153782.2 140000.0 132157.3 134129.0 126479.9 False True 136830.83966730846 126357.74739091413 159873.726625689 148533.41622309122 139319.68406490327 147205.2937898172 147248.51497473888 138297.81062194335 119021.97957901371 148341.7821911269 0.922402560129772 0.8518014649986607 1.077739017721279 1.0012918412407734 0.9391803307675018 0.9923387168165108 0.9926300789956842 0.9322916886879338 0.8023496672411763 1.0 17.178565481332548 -10.197260844312364 5.327814651327156 1.0000000042589354 0.9506867423955855 0.04211447652048983 0.07433050759787507 104508416.6126508 32.73369431321162 5.498317872452545 0.01851966651875099 6.349494563573291e-11 10.197260844312364 -0.049313261863349944 FNDFDHR ddPTM_PC-9_AZD4547_30min_R2 3 FNDFDHR 7 0 Q9NWH9;Q9NWH9-3;H7C3F4;H0YMM0 Q9NWH9 SLTM SAFB-like transcription modulator 0 ;; 124.08 5.8994e-05 6651100.0 71912.0 74021.0 97339.0 135712.0 104163.0 99305.0 81369.0 101529.0 81854.0 99855.0 False True 94778.5201374793 97946.84069045143 96048.22125982714 104425.6951294987 89701.7654342578 93095.44265156976 88610.68336736016 85840.02595431979 86180.63533174696 96359.1068434967 0.9835969141081337 1.0164772578219667 0.9967736771971695 1.083713813361756 0.9309111341178002 0.9661301946558338 0.9195880521316862 0.8908345953614778 0.894369387127246 1.0 16.556133400788454 -6.338102034880882 11.293461496985556 0.9290278605393989 1.0181881115093343 0.5409645382497701 0.038881184434433745 0.6129879556144382 88.82723464839405 0.012132829574784293 0.013756966236774108 4.5909013969349196e-07 6.338102034880882 0.0891602509699354 FNDFDHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FNDFDHR 7 0 Q9NWH9;Q9NWH9-3;H7C3F4;H0YMM0 Q9NWH9 SLTM SAFB-like transcription modulator 0 ;; 122.52 0.00011472 5690600.0 62894.0 63321.0 72241.0 71194.0 84025.0 72866.0 76252.0 75262.0 67051.0 61085.0 False True 73540.71198687686 69607.09040608979 73963.49941551813 67205.2309940622 67560.9044285093 69044.77868673808 69028.85854332703 73286.45224668072 68031.49402697067 72159.22695140619 1.0191449533737522 0.96463187518576 1.025004043700842 0.9313463271900054 0.9362753355715199 0.9568392235304092 0.9566185983368805 1.0156213604676452 0.9427968799164764 1.0 16.138896262497695 -3.635501111028866 0.9019725988770468 0.9658102502104036 1.3273003409980515 0.17598931385040884 0.03136858861570851 25.768986005465848 3.343094385000939 0.010576743900422673 14.770642922476819 0.00023147222643960427 3.635501111028866 0.36149009078764793 FNDFDHR ddPTM_PC-9_Lapatinib_30min_R1 4 FNDFDHR 7 0 Q9NWH9;Q9NWH9-3;H7C3F4;H0YMM0 Q9NWH9 SLTM SAFB-like transcription modulator 0 ;;; 126.41 0.0038215000000000002 13538500.0 137089.0 135173.0 142970.0 129425.0 137876.0 131569.0 129452.0 136391.0 149387.0 104927.0 False True 135134.0857209565 134860.0152235046 131215.55848015955 138943.34624914336 129766.40475464542 125942.10057231883 136154.39114649926 142728.22377982526 132561.46294515065 123063.49214356104 1.0980842763938015 1.095857210570477 1.06624276781524 1.1290378960403424 1.0544671087609396 1.0233912460845798 1.1063751627303642 1.1597933822105755 1.0771794350716917 1.0 16.90904331168462 FNDPSGCAPS(ph)PGAYDVK ddPTM_PC-9_AZD4547_30min_R2 2 FNDPSGCAPSPGAYDVK 17 0 O75330-2;O75330;O75330-3 O75330-2 HMMR Hyaluronan mediated motility receptor 1 FNDPSGCAPS(1)PGAYDVK;FNDPSGCAPS(1)PGAYDVK 196.83 3.2639e-12 23698000.0 93691.0 94146.0 115949.0 136461.0 125504.0 118502.0 93462.0 140872.0 106699.0 116815.0 True False 123482.78910613731 124576.8533746267 114411.44050026938 105002.02475143339 108079.93595673212 111092.05120685075 101779.93694011502 119103.46931651999 112338.89130967425 112725.34240571901 1.0954305968013855 1.1051361718312813 1.014957577937371 0.931485524998558 0.9587900435709724 0.985510878352538 0.9029019985034998 1.056581126964733 0.9965717460883475 1.0 16.782452366636974 -5.386752843971965 3.602165915231381 0.9748171933403897 1.1007129374173525 0.607065661927955 0.039348487826381194 0.15547883982363056 3.6002619868070256 0.010862047152302119 0.025080005473708998 4.104376156728156e-06 5.386752843971965 0.1258957440769628 FNDPSGCAPS(ph)PGAYDVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FNDPSGCAPSPGAYDVK 17 0 O75330-2;O75330;O75330-3 O75330-2 HMMR Hyaluronan mediated motility receptor 1 FNDPS(0.015)GCAPS(0.985)PGAYDVK;FNDPS(0.088)GCAPS(0.912)PGAYDVK 178.56 3.2811000000000002e-06 12304200.0 95573.0 95252.0 82826.0 88430.0 98238.0 76305.0 73436.0 77569.0 56975.0 48113.0 True False 111751.6212472062 104707.98906146245 84800.88595935435 83475.55379392818 78988.96910738353 72303.43147272464 66479.61044940157 75532.8959411492 57808.15158888976 56835.50603770157 1.9662290184075477 1.842298879014201 1.4920406603418306 1.4687219242590197 1.3897821030217723 1.2721525066524875 1.1696844997791105 1.3289737561418877 1.0171133437352171 1.0 15.79450486528011 -1.5228787452826942 0.24701885782771682 1.0144693789624348 7.279510715107457 0.9356486970895143 0.0765368454335836 11.110496523575632 0.15032760209468146 0.0980713037161825 28.806428248876134 0.02999999999983721 1.5228787452826942 6.265041336145022 FNDPSGCAPS(ph)PGAYDVK ddPTM_PC-9_Lapatinib_30min_R1 2 FNDPSGCAPSPGAYDVK 17 0 O75330-2;O75330;O75330-3 O75330-2 HMMR Hyaluronan mediated motility receptor 1 FNDPSGCAPS(0.987)PGAY(0.013)DVK;FNDPS(0.026)GCAPS(0.974)PGAYDVK 149.74 5.9785e-05 24725000.0 112190.0 142455.0 162225.0 125258.0 105747.0 111924.0 96417.0 76551.0 113134.0 81752.0 True False 110590.1500268739 142125.15419990933 148887.48670660914 134469.89116843918 99527.1693666011 107137.27142758711 101409.00048799568 80107.83892316482 100391.65756616503 95882.72427230717 1.1533897359111076 1.4822811437467458 1.5528082648524704 1.402441286362957 1.0380094028611837 1.1173782580824154 1.0576357864008314 0.8354772930278698 1.0470255025405044 1.0 16.54898327975794 -6.269607568413332 4.771814605477321 1.012121122695482 1.4176413269025048 0.7166332417003008 0.11748440533275928 0.10422806207286198 6.870222819318378 0.03787318116495626 0.045779065770748806 5.375172814367632e-07 6.269607568413332 0.4055202042070227 FNDS(ph)EGDDTEETEDYR ddPTM_PC-9_AZD4547_30min_R2 1 FNDSEGDDTEETEDYR 16 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 FNDS(0.858)EGDDT(0.141)EET(0.002)EDYR 187.5 1.1307999999999999e-38 0.0 7820.7 12105.0 15674.0 12229.0 12996.0 12774.0 13385.0 18087.0 15016.0 14051.0 True False 10307.519919334509 16017.70452382318 15466.152518790337 9409.792986166585 11191.72972728907 11975.239760648052 14576.239069819174 15292.069747912241 15809.71510422842 13559.078766791545 0.7601932326390309 1.1813269027578202 1.1406492125902783 0.6939846834736844 0.8254048759344544 0.8831897776106604 1.075016918223001 1.1278103778971387 1.1659874078576091 1.0 13.726971541524453 -7.357852189013235 4.866721475217238 1.1078347027704338 0.9228237993074304 0.2553737948254201 0.1482894819544263 0.3593310105573146 13.852551089419864 0.06898578100169131 0.0457058731042614 4.386799759484779e-08 7.357852189013235 -0.18501090346300342 FNDS(ph)EGDDTEETEDYR ddPTM_PC-9_Lapatinib_30min_R1 3 FNDSEGDDTEETEDYR 16 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 FNDS(1)EGDDTEETEDYR;FNDS(0.981)EGDDT(0.019)EETEDYR;FNDS(0.969)EGDDT(0.025)EET(0.006)EDYR 235.79 4.4814999999999995e-109 0.0 20810.8 30026.4 29020.0 26522.5 29908.6 28939.3 25575.0 29826.6 26966.1 23090.4 True False 20514.034175766683 29956.87571561651 26634.08762043948 28473.053126466326 28149.43495057 27701.633599803215 26899.14836056391 31212.452723356637 23928.893852378234 27081.544873975974 0.7574912831313274 1.1061730730289165 0.983477410331695 1.0513821592883914 1.0394323913780936 1.0228970957422416 0.9932649147505859 1.1525359010574858 0.8835867364188931 1.0 14.72502241973459 -4.751357096480872 24.997768807178915 1.0294137154825362 0.7574907285788033 0.5780947766492304 0.06871979634430979 274.6982605221149 681034.1104083026 0.015482578175810705 0.20663014166972216 1.7727312619895914e-05 4.751357096480872 -0.27192298690373295 FNDS(ph)EGDDTEETEDYRQFR ddPTM_PC-9_AZD4547_30min_R2 2 FNDSEGDDTEETEDYRQFR 19 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 FNDS(0.994)EGDDT(0.005)EET(0.002)EDYRQFR;FNDS(0.472)EGDDT(0.231)EET(0.161)EDY(0.136)RQFR 65.365 0.0050171999999999994 27634000.0 7267.4 3302.6 9078.8 23014.7 15398.6 8556.5 3908.8999999999996 6081.799999999999 4774.9 8226.8 True False 9578.282028689451 4370.100864137004 8958.409180017465 17709.016488570454 13260.770189183871 8021.4607023630015 4256.784527457313 5141.99755586071 5027.291465848446 7938.782236043033 1.20651779377483 0.5504749638170218 1.1284361900424982 2.2306968451873357 1.6703783773005347 1.0104145023583841 0.5362011957112258 0.6477060842550156 0.633257257394457 1.0 12.95470200780348 -7.002692545880338 5.724233026121856 0.6848528268034579 1.349692836186911 0.35604157005377446 0.41398125204163355 0.206621257541172 24.934418277842582 0.17398614268607623 0.1445921916842146 9.938193631966744e-08 7.002692545880338 0.664840009383453 FNDS(ph)EGDDTEETEDYRQFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FNDSEGDDTEETEDYRQFR 19 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 FNDS(0.999)EGDDT(0.001)EETEDYRQFR;FNDS(0.963)EGDDT(0.035)EET(0.002)EDYRQFR 69.525 0.0036209000000000002 10513200.0 5258.799999999999 4820.7 9456.1 9020.7 9093.8 16729.6 8010.0 12612.7 10499.7 5986.9 True False 6149.010973965526 5299.267237103599 9681.56928645895 8515.29942450399 7311.935170389515 15852.270325222375 7251.234812621951 12281.629989260296 10653.238249019148 7072.2775777256775 0.8694527196347605 0.7493013642159322 1.3689464504265647 1.2040391982525045 1.033886904187506 2.241466083733692 1.0253040456811118 1.7365876627837133 1.5063376871082945 1.0 12.78795918441256 -5.400862327733402 0.9388825270797443 1.4807620260571288 0.6873770507727838 0.2638353383436134 0.3691808322992724 1.204244002970192 1.5488965002492732 0.13471333425875245 0.8026309982299884 3.973174799872797e-06 5.400862327733402 -0.793384975284345 FNDS(ph)EGDDTEETEDYRQFR ddPTM_PC-9_Lapatinib_30min_R1 2 FNDSEGDDTEETEDYRQFR 19 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 FNDS(0.989)EGDDT(0.01)EET(0.001)EDYRQFR;FNDS(1)EGDDTEETEDYRQFR 123.36 1.2736e-05 28718000.0 70359.0 9181.599999999999 23708.0 16249.4 10936.9 16111.5 5248.7 3764.5 17164.5 5551.6 True False 69355.66775773953 9160.34056931582 21758.819755526525 17444.435082409353 10293.613044772708 15422.44870274089 5520.452003913661 3939.4124129829074 15231.253259801995 6511.186662957989 10.651770767424399 1.4068619198753454 3.3417594797753254 2.679148361949197 1.5809119869551378 2.3686079820870276 0.8478411524153351 0.6050221897943958 2.3392438349912914 1.0 12.668704783006913 -4.759723458051191 24.999849671054914 1.841608349710194 10.65178172122261 0.9102185322691121 0.8342238400690238 12.661009000753667 184408.03689783672 0.2197919158772865 1.367257386104751 1.738907745567525e-05 4.759723458051191 8.810173371512416 FNDSEGDDT(ph)EETEDYR ddPTM_PC-9_AZD4547_30min_R2 2 FNDSEGDDTEETEDYR 16 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 FNDS(0.001)EGDDT(0.999)EETEDYR;FNDSEGDDT(0.858)EET(0.142)EDYR 292.38 4.075499999999999e-111 263757000.0 52340.0 59566.0 62773.0 69352.0 66451.0 69051.0 59794.0 72587.0 59139.0 65740.0 True False 68983.03126036907 78819.54462338304 61940.58900485039 53363.96787771892 57225.425677753614 64733.230054212276 65115.55016367333 61370.34703332258 62264.96680533864 63438.462609698676 1.0874007411683826 1.2424567270539886 0.9763885576158449 0.8411926405915212 0.9020619876908053 1.0204098175026652 1.0264364469910445 0.9673996580103138 0.9815018246646376 1.0 15.953070188229438 -5.3187725893702575 7.987982156066922 0.9604620441192041 1.1645391840108905 0.616987979296578 0.06314663988160978 0.18585610871450675 23.919574165929546 0.017558316031177287 0.03687548145646002 4.79984718359008e-06 5.3187725893702575 0.2040771398916864 FNDSEGDDT(ph)EETEDYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FNDSEGDDTEETEDYR 16 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 FNDS(0.354)EGDDT(0.646)EETEDYR 162.64 0.00015435 64518000.0 19764.0 25518.0 26064.0 32432.0 25828.0 26010.0 24688.0 27696.0 22308.0 20718.0 True False 23109.654843206576 28051.258397413163 26685.464608270446 30614.940185962652 20767.188807849358 24645.989812011885 22349.373914358384 26969.009346337658 22634.212297410315 24474.00939640223 0.944252920267481 1.1461652213607796 1.090359334919325 1.250916418723904 0.8485405260530059 1.0070270633970966 0.9131880907769785 1.1019448799550677 0.9248264937226683 1.0 14.57896284641334 -6.266378629074401 24.994418277619957 0.9704370656460161 1.1094004442100363 0.35228621788915426 0.09420103300301842 479.97877635594455 2428865.5710389293 0.02810250248917953 0.03284420467482906 5.415285660384468e-07 6.266378629074401 0.1389633785640202 FNDSEGDDTEET(ph)EDYR ddPTM_PC-9_Lapatinib_30min_R1 1 FNDSEGDDTEETEDYR 16 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 FNDS(0.14)EGDDT(0.081)EET(0.779)EDYR 238.83 7.1476e-37 141090000.0 10083.0 13216.0 12662.0 10460.0 14186.0 15228.0 11414.0 16036.0 13575.0 11992.0 True False 9939.214571004262 13185.399163988628 11620.979236733454 11229.263293537104 13351.607370749078 14576.733938201794 12004.96107086908 16781.091102296166 12046.040548912702 14064.801221664415 0.7066729500374741 0.9374749743123836 0.8262455368962718 0.7983947385079534 0.9492922907565317 1.0363981480057347 0.8535464441813437 1.1931267877748442 0.8564671735536399 1.0 13.779801542685853 -6.38840666396322 4.2525969363898195 0.9917117087144504 0.8268891718388174 0.377015399275353 0.10383615339946964 0.25059726682293926 7.4857979870428375 0.031199803649905482 0.03548889023043664 4.088776162614307e-07 6.38840666396322 -0.16482253687563297 FNEEHIPDSPFVVPVAS(ph)PSGDAR ddPTM_PC-9_AZD4547_30min_R2 2 FNEEHIPDSPFVVPVASPSGDAR 23 0 Q60FE5;P21333-2;P21333;A0A087WWY3;H0Y5C6 Q60FE5 FLNA Filamin-A 1 FNEEHIPDS(0.001)PFVVPVAS(0.5)PS(0.5)GDAR;FNEEHIPDS(0.014)PFVVPVAS(0.641)PS(0.344)GDAR 96.46 4.9663e-06 7252000.0 15890.2 13560.6 17981.8 22527.0 19040.7 17305.8 16156.900000000001 17139.4 15759.3 18163.8 True False 20942.953063307545 17943.798758013752 17743.349582900595 17333.74818868056 16397.22747140606 16223.665590247607 17594.832799937354 14490.899554230515 16592.304424751394 17527.890890630442 1.1948358872146236 1.0237283464381692 1.0122923341783994 0.9889237842041988 0.9354934700198995 0.9255914297663724 1.0038191651080335 0.8267337835824072 0.9466229866606959 1.0 14.097364788385686 -1.5228787453211137 0.5995347184927826 0.9320077621867684 16.877444822905332 0.7000061197626151 0.048794546660549484 89.88163058776375 0.6975500484138517 0.02150844934044457 1877.2071385135687 0.029999999997183287 1.5228787453211137 15.945437060718564 FNEEHIPDSPFVVPVAS(ph)PSGDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FNEEHIPDSPFVVPVASPSGDAR 23 0 Q60FE5;P21333-2;P21333;A0A087WWY3;H0Y5C6 Q60FE5 FLNA Filamin-A 1 FNEEHIPDSPFVVPVAS(0.5)PS(0.5)GDAR 118.11 1.3123e-08 7367200.0 23524.0 25765.0 28290.0 33910.0 37028.0 26124.0 28007.0 29651.0 27457.0 21114.0 True False 27506.148579821467 28322.77892504702 28964.540890422464 32010.13263770333 29772.629207722086 24754.011451326354 25353.974206879266 28872.69266783138 27858.506681459327 24941.80106166797 1.1028132455957456 1.1355546800738112 1.1612850579157603 1.283392989887101 1.1936840140016358 0.9924708881336471 1.0165253962290937 1.1576025563047503 1.1169404572099615 1.0 14.606278026309619 -6.742717886646946 24.997013478661742 1.06404660843058 1.1783568447374064 0.45286809204665757 0.06490888210615385 260.867903652707 348311.24786916166 0.0234592505874373 0.0234205125111803 1.8083484296203985e-07 6.742717886646946 0.11431023630682646 FNEEHIPDSPFVVPVAS(ph)PSGDAR ddPTM_PC-9_Lapatinib_30min_R1 3 FNEEHIPDSPFVVPVASPSGDAR 23 0 Q60FE5;P21333-2;P21333;A0A087WWY3;H0Y5C6 Q60FE5 FLNA Filamin-A 1 FNEEHIPDS(0.001)PFVVPVAS(0.818)PS(0.182)GDAR;FNEEHIPDSPFVVPVAS(0.83)PS(0.17)GDAR;FNEEHIPDSPFVVPVAS(0.5)PS(0.5)GDAR 123.22 3.6643000000000002e-06 6788500.0 48757.6 40595.5 42894.7 42278.9 44279.6 49012.5 40159.6 39185.1 51078.8 35871.8 True False 48062.30768295125 40501.50361393008 39368.063344330316 45388.23134427587 41675.160985043105 46916.34962871786 42238.86758556808 41005.78279824055 45325.76766039056 42072.192833831 1.1423770534799291 0.9626668087849725 0.9357264428744906 1.0788178197305271 0.9905630816450186 1.1151391564974855 1.0039616369033908 0.9746528534939369 1.077333141141702 1.0 15.36057939394918 -4.745722427579963 24.958394193426646 1.016107622739184 1.142377409786459 0.32892288431164585 0.05439066123487303 1087.60454773226 1727010.7499047923 0.013546612469202666 0.3330729304800161 1.7958810689692978e-05 4.745722427579963 0.12626978704727487 FNEEHIPDSPFVVPVAS(ph)PSGDARR ddPTM_PC-9_AZD4547_30min_R2 4 FNEEHIPDSPFVVPVASPSGDARR 24 1 Q60FE5;P21333-2;P21333;A0A087WWY3;H0Y5C6 Q60FE5 FLNA Filamin-A 1 FNEEHIPDSPFVVPVAS(0.937)PS(0.063)GDARR;FNEEHIPDS(0.001)PFVVPVAS(0.906)PS(0.093)GDARR;FNEEHIPDSPFVVPVAS(0.817)PS(0.183)GDARR;FNEEHIPDSPFVVPVAS(0.782)PS(0.218)GDARR 157.02 1.2371e-07 12619200.0 44117.7 32600.300000000003 53968.0 109140.0 77589.0 56413.6 47380.7 57132.899999999994 42607.3 57314.1 True False 58146.21089483345 43137.709441387255 53252.3490579352 83979.45919619112 66817.10663362806 52886.04867397013 51597.49051142185 48304.32308843342 44859.43489347308 55307.55080405435 1.0513250008273918 0.7799605806848533 0.962840485318173 1.518408571258501 1.2081009855299902 0.9562175128914457 0.9329194614714248 0.8733766436262523 0.811090605917495 1.0 15.755188835848815 -6.936798704017601 6.0847161021592004 0.9004120004283792 1.1009700704792036 0.2171813860174293 0.18169804355106153 0.36707803208439227 25.97436725522416 0.073130927987462 0.06416874434115231 1.1566482257257463e-07 6.936798704017601 0.20055807005082438 FNEEHIPDSPFVVPVAS(ph)PSGDARR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FNEEHIPDSPFVVPVASPSGDARR 24 1 Q60FE5;P21333-2;P21333;A0A087WWY3;H0Y5C6 Q60FE5 FLNA Filamin-A 1 FNEEHIPDSPFVVPVAS(0.788)PS(0.211)GDARR;FNEEHIPDSPFVVPVAS(0.95)PS(0.05)GDARR;FNEEHIPDSPFVVPVAS(0.6)PS(0.4)GDARR 126.09 8.5921e-08 12386600.0 29224.2 12680.0 21796.1 37208.0 39022.0 44239.0 36310.4 49237.0 38748.0 29878.4 True False 34171.27985573962 13938.786600799383 22315.801686169565 35123.35638996361 31375.919221770848 41919.028961691394 32870.81604746916 47944.580920913766 39314.616195985946 35295.11740271574 0.9681588381148254 0.3949211003255334 0.6322631380297521 0.9951335758203508 0.8889591969272403 1.1876721780918622 0.931313407245954 1.3583913144095316 1.113882573258162 1.0 15.107180999700477 -6.0928855955310395 1.3846228806655336 1.1234766422491322 0.6371784451667045 0.5001521686602858 0.1827362973134272 0.3206316049362412 1.2417311236082829 0.06534805963529933 0.10733144045584352 8.074477049747353e-07 6.0928855955310395 -0.4862981970824277 FNEEHIPDSPFVVPVAS(ph)PSGDARR ddPTM_PC-9_Lapatinib_30min_R1 2 FNEEHIPDSPFVVPVASPSGDARR 24 1 Q60FE5;P21333-2;P21333;A0A087WWY3;H0Y5C6 Q60FE5 FLNA Filamin-A 1 FNEEHIPDSPFVVPVAS(0.6)PS(0.4)GDARR;FNEEHIPDSPFVVPVAS(0.921)PS(0.079)GDARR 105.77 5.338e-07 5763700.0 80600.0 33854.0 47663.0 33891.0 29327.1 38218.4 24547.6 24511.5 40997.0 27252.4 True False 79450.62921977008 33775.61314298355 43744.33212450059 36383.45719706177 27602.137637297015 36583.8881234418 25818.554615670728 25650.39377363012 36379.486142451125 31962.941028459587 2.485710847103456 1.056711680971722 1.3685953393822845 1.138301296012347 0.863566891817629 1.1445720245476707 0.8077652989655133 0.8025041797871848 1.1381770566750748 1.0 14.964112541631371 -2.890369554556494 1.3035491603757756 0.9972535427734358 199.99999999999866 0.8506952657951399 0.18016257966421437 71.04355438979839 1.1755690984212972 0.05250231227347793 41289.88759669168 0.0012871538067226796 2.890369554556494 199.00274645722521 up FNEEHIPDSPFVVPVASPS(ph)GDAR ddPTM_PC-9_AZD4547_30min_R2 4 FNEEHIPDSPFVVPVASPSGDAR 23 0 Q60FE5;P21333-2;P21333;A0A087WWY3;H0Y5C6 Q60FE5 FLNA Filamin-A 1 FNEEHIPDSPFVVPVAS(0.433)PS(0.567)GDAR;FNEEHIPDSPFVVPVAS(0.405)PS(0.595)GDAR;FNEEHIPDSPFVVPVAS(0.385)PS(0.615)GDAR;FNEEHIPDSPFVVPVAS(0.405)PS(0.595)GDAR 139.52 2.0814e-08 116111700.0 110404.2 107088.3 171196.3 216162.0 174282.0 152922.7 130339.0 168905.6 132192.7 157575.4 True False 145510.43904998177 141702.498749156 168926.1252043248 166329.19056960824 150085.95262629993 143360.41939452398 141938.91849990017 142805.12058456146 139180.1362452542 152058.73320821923 0.956935757518967 0.9318931952110762 1.110926821763065 1.0938483246591828 0.9870261934957862 0.9427963548677973 0.9334479875321489 0.939144484315896 0.9153051147326742 1.0 17.214269151669527 -6.58969904919158 4.290862678775228 0.9421078136189595 1.024978626832759 0.3057640138436051 0.05450471330332358 0.278405110590577 10.190492380460084 0.020121895615142715 0.020327810995191847 2.5721775939795153e-07 6.58969904919158 0.08287081321379952 FNEEHIPDSPFVVPVASPS(ph)GDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 FNEEHIPDSPFVVPVASPSGDAR 23 0 Q60FE5;P21333-2;P21333;A0A087WWY3;H0Y5C6 Q60FE5 FLNA Filamin-A 1 FNEEHIPDSPFVVPVAS(0.393)PS(0.606)GDAR;FNEEHIPDSPFVVPVAS(0.418)PS(0.582)GDAR;FNEEHIPDSPFVVPVAS(0.396)PS(0.604)GDAR;FNEEHIPDSPFVVPVAS(0.389)PS(0.611)GDAR;FNEEHIPDSPFVVPVAS(0.418)PS(0.582)GDAR 151.03 1.9498999999999998e-08 89520400.0 133883.0 150826.0 164117.0 182767.0 180372.0 158257.0 175505.0 160926.0 159670.0 133262.0 True False 156546.7475902156 165799.0085056916 168030.17169718817 172527.15752860886 145029.40141123586 149957.72432447365 158879.89585383487 156701.863015191 162004.8716840375 157421.34569858856 0.9944442216238734 1.0532180865938192 1.0673912800803527 1.095957836994629 0.921281677320436 0.9525882507166128 1.0092652629081127 0.9954295735422365 1.0291162927435833 1.0 17.264271652166215 -6.250847195585484 24.948182626099808 0.9840163114351624 1.053831686505229 0.45264713487350894 0.036696516639867505 692.6516195897835 1631428.6790566365 0.011563801624655727 0.014766756755947547 5.612454127828435e-07 6.250847195585484 0.06981537507006663 FNEEHIPDSPFVVPVASPS(ph)GDAR ddPTM_PC-9_Lapatinib_30min_R1 3 FNEEHIPDSPFVVPVASPSGDAR 23 0 Q60FE5;P21333-2;P21333;A0A087WWY3;H0Y5C6 Q60FE5 FLNA Filamin-A 1 FNEEHIPDSPFVVPVAS(0.422)PS(0.578)GDAR;FNEEHIPDSPFVVPVAS(0.394)PS(0.606)GDAR;FNEEHIPDSPFVVPVAS(0.379)PS(0.621)GDAR 173.4 2.7335e-14 82960700.0 145827.0 133888.0 152996.0 120796.0 131970.0 140173.0 122271.0 125979.0 144364.0 105630.0 True False 143747.48023860378 133577.99056205392 140417.25946163916 129679.74080364294 124207.78406300285 134178.12754922238 128601.59410340234 131832.4442489502 128104.20609968578 123888.00475687197 1.160301842948441 1.0782156902453823 1.1334209452901074 1.046749772571906 1.0025811966764533 1.0830598798692785 1.038047181046952 1.0641259781983659 1.0340323613338356 1.0 16.91867698220964 -1.5228787452811003 0.37495685672527146 1.0320135257885295 2.698820072904722 0.597489404595984 0.03133639062340071 49.57020008409875 0.6809299725113024 0.02453581328163953 59.771032685199195 0.02999999999994731 1.5228787452811003 1.6668065471161924 FNEEHIPDSPFVVPVASPSGDAR ddPTM_PC-9_AZD4547_30min_R2 2 FNEEHIPDSPFVVPVASPSGDAR 23 0 Q60FE5;P21333-2;P21333;A0A087WWY3;H0Y5C6 Q60FE5 FLNA Filamin-A 0 ; 121.5 9.9395e-09 12488700.0 45278.0 47016.0 68497.0 96723.0 80028.0 65766.0 56076.0 88935.0 68045.0 72751.0 False True 59675.46215909422 62213.00255200916 67588.68502485532 74425.00670545339 68917.49358383272 61653.641623514945 61066.65536639369 75192.13927299033 71641.7197833793 70204.00963368083 0.8500292571674499 0.8861744916940194 0.962746791494217 1.0601247292540326 0.9816746072402267 0.8782068423900421 0.8698456923619439 1.07105191947493 1.0204790318558774 1.0 16.099265810555508 -5.2099102934357235 3.2663736561933123 0.9790669162494315 0.8585192272694527 0.34597938275205165 0.0628593785178519 0.3183179539357621 6.757825683377612 0.018444412909920098 0.0572998768495464 6.167223770284938e-06 5.2099102934357235 -0.1205476889799788 FNEEHIPDSPFVVPVASPSGDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FNEEHIPDSPFVVPVASPSGDAR 23 0 Q60FE5;P21333-2;P21333;A0A087WWY3;H0Y5C6 Q60FE5 FLNA Filamin-A 0 ; 104.67 2.2061e-06 14828900.0 24232.0 23175.0 23798.0 27818.0 36167.0 26532.0 22985.8 24873.0 23537.5 20441.2 False True 28333.998996184062 25475.660841760717 24365.434574417588 26259.447647172827 29080.33597698184 25140.615213083405 20808.418621219178 24220.110105121916 23881.691408924828 24147.027747549844 1.1733948911811336 1.0550226350050758 1.0090448741414937 1.0874815700593763 1.2043029179826312 1.0411474023188787 0.8617382991714403 1.0030265570709624 0.9890116356597164 1.0 14.559557998516622 -7.00538668521154 24.994139028746766 0.9619458300512469 1.099237008303573 0.5243430728102088 0.06377759185640433 205.10071739508223 951667.2122280246 0.023656902526851036 0.020259016195862314 9.876733028291351e-08 7.00538668521154 0.13729117825232606 FNEEHIPDSPFVVPVASPSGDAR ddPTM_PC-9_Lapatinib_30min_R1 2 FNEEHIPDSPFVVPVASPSGDAR 23 0 Q60FE5;P21333-2;P21333;A0A087WWY3;H0Y5C6 Q60FE5 FLNA Filamin-A 0 ; 150.95 3.4189e-07 27953000.0 45084.0 43853.0 49488.0 47939.0 49034.0 47087.0 44266.0 40511.0 43170.0 40217.0 False True 44441.09389260696 43751.46107282029 45419.28766920435 51464.59397981597 46149.91652455311 45073.198775158125 46557.87688479856 42393.288952676456 38307.73999974666 47168.454864215986 0.942178284629838 0.9275576484064995 0.9629165890626061 1.0910807684493227 0.9784063662336419 0.9555792935111086 0.9870553745893289 0.8987635714316736 0.8121474428200647 1.0 15.525534721645624 -7.78755568569209 7.036025437886447 0.8907835399097294 0.9788842079714268 0.23721659213203006 0.059661802022087505 0.2301566749659109 40.482838173579 0.0325529615824232 0.016024664928730874 1.630963771941845e-08 7.78755568569209 0.08810066806169747 FNENNRR ddPTM_PC-9_AZD4547_30min_R2 1 FNENNRR 7 1 P17931;G3V3R6 P17931 LGALS3 Galectin-3;Galectin 0 66.07300000000001 0.034927 6435200.0 6982.8 4492.8 5436.4 8098.0 7617.0 5916.2 5920.9 6333.2 6987.5 10430.0 False True 9203.185148737202 5945.0097385074605 5364.309783919342 6231.131212852806 6559.511028990528 5546.25907874949 6447.848629696845 5354.549462458 7356.844984736018 10064.84887464492 0.9143888063656478 0.5906705418582051 0.5329746974575007 0.6190983382323896 0.6517247412939364 0.5510523951056501 0.6406304466170457 0.5320049539886315 0.7309444062562303 1.0 13.297037889668893 -8.587375234005208 6.145533934107183 0.9999912762231828 0.6230914340060195 0.5355554389670888 0.10424633107135077 0.4898708946606064 45.78938204966529 0.09788296451592428 0.025361232704817754 2.5859776436872734e-09 8.587375234005208 -0.37689984221716333 FNGEDIDTIS(ph)PTLGFNIK ddPTM_PC-9_AZD4547_30min_R2 1 FNGEDIDTISPTLGFNIK 18 0 V9GYD0;P36404-2;P36404 V9GYD0 ARL2-SNX15;ARL2 ADP-ribosylation factor-like protein 2 1 FNGEDIDT(0.165)IS(0.829)PT(0.007)LGFNIK 98.07700000000001 0.00073327 8463000.0 20972.0 9549.1 16524.0 23898.0 21231.0 24646.0 19415.0 22883.0 19731.0 21262.0 True False 27640.659755301123 12635.659832171816 16304.880963410189 18388.685320419405 18283.4421237361 23104.881723886934 21142.897388161324 19346.958149028367 20773.94037836515 20517.623851649136 1.3471667067860522 0.6158442090337963 0.7946768632323699 0.8962385436723651 0.8911091389496615 1.1260992935119942 1.0304749488066052 0.9429434075268577 1.0124925053977638 1.0 14.324576041491667 -6.655537494161716 10.406523261650628 1.0192505848493099 0.8850553474985159 0.08570586863499341 0.17666479315269165 0.7517714825074042 68.5770402062201 0.05687485026141911 0.05685347076709311 2.2103574201741848e-07 6.655537494161716 -0.13419523735079397 FNGEDIDTIS(ph)PTLGFNIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FNGEDIDTISPTLGFNIK 18 0 V9GYD0;P36404-2;P36404 V9GYD0 ARL2-SNX15;ARL2 ADP-ribosylation factor-like protein 2 1 FNGEDIDT(0.088)IS(0.554)PT(0.358)LGFNIK 130.95 4.1039e-05 1758400.0 6421.3 7890.7 7172.7 9504.0 10225.0 8076.4 9226.3 6608.9 6169.7 7051.0 True False 7508.299263543939 8674.03654818042 7343.724370616227 8971.521692383736 8221.484650776656 7652.859366310375 8352.318071372521 6435.423377708371 6259.920190574346 8329.29048431471 0.9014332346414357 1.0413896074959708 0.8816746617788814 1.077105151906809 0.9870570207941399 0.9187888669175177 1.0027646516952646 0.7726256383814718 0.7515550336925702 1.0 13.023977892094836 -7.756715416274979 24.99938955992285 0.8215677410091224 0.9744867371872461 0.3273485204104911 0.08494265022710591 109.86150650203052 581400.4017195237 0.03909355373033298 0.021621843199550208 1.750993700853234e-08 7.756715416274979 0.15291899617812366 FNGGHS(ph)PTHSPEK ddPTM_PC-9_AZD4547_30min_R2 2 FNGGHSPTHSPEK 13 0 Q9Y5K6 Q9Y5K6 CD2AP CD2-associated protein 1 FNGGHS(0.578)PT(0.408)HS(0.014)PEK;FNGGHS(0.999)PT(0.001)HSPEK 89.311 0.0034963 111654000.0 80383.0 70284.0 113240.0 150952.0 142251.0 109518.0 88200.0 129988.0 104288.0 113021.0 True False 105943.12192973359 93001.92852146953 111738.36361029839 116152.34858515144 122501.90408099421 102669.82214706844 96049.6291339597 109901.34142708141 109800.4507718282 109064.16919091529 0.9713833857229651 0.8527266948567771 1.0245194589499138 1.0649909080756705 1.1232094370659567 0.9413707811531243 0.8806708000115617 1.0076759603302956 1.0067509025775832 1.0 16.734817685896893 -5.2779154086063915 24.494159146732212 1.0059100975942006 0.9120550336580338 0.24135785489325756 0.06672679777438174 849.4437410665685 1262829.0261702528 0.019221146845359045 0.0402108490256706 5.273325646676316e-06 5.2779154086063915 -0.09385506393616683 FNGGHS(ph)PTHSPEK ddPTM_PC-9_Lapatinib_30min_R1 2 FNGGHSPTHSPEK 13 0 Q9Y5K6 Q9Y5K6 CD2AP CD2-associated protein 1 FNGGHS(0.991)PT(0.009)HSPEK;FNGGHS(0.995)PT(0.005)HS(0.001)PEK 64.476 0.023784 117550000.0 146700.0 107048.0 119309.0 114919.0 134642.0 130621.0 97734.0 99874.0 134500.0 91592.0 True False 144608.03109851465 106800.13693300937 109499.87456605835 123370.5266185459 126722.6222763567 125034.64432242302 102794.18830386527 104514.51064796274 119351.19365221057 107423.55516133129 1.3461482528793505 0.9941966338073093 1.0193283437846457 1.1484494851549558 1.1796539603073237 1.1639406658497102 0.9569054771040344 0.9729198637207671 1.1110337343887573 1.0 16.712950847540284 -7.256076865347438 24.781866240438333 1.0079580902423022 1.1316718403428552 0.2999838173941719 0.0978098401980878 554.2485442956346 2561365.599740259 0.0387009152308926 0.029079020664555148 5.545275589921792e-08 7.256076865347438 0.12371375010055297 FNGS(ph)TEALDKLDADAVSPTVSQLSAVFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FNGSTEALDKLDADAVSPTVSQLSAVFEK 29 1 Q96SB3 Q96SB3 PPP1R9B Neurabin-2 1 FNGS(0.683)T(0.284)EALDKLDADAVS(0.019)PT(0.008)VS(0.004)QLS(0.002)AVFEK 43.425 0.018725 1550500.0 969.91 718.11 1200.6 4015.1 2929.0 3464.5 3701.3 4002.4 3501.4 2337.7 True False 1134.096606404295 789.3992149763441 1229.2268573008557 3790.1469641298313 2355.0834760024286 3282.815521096313 3350.6860689085697 3897.3412408933364 3552.6013510019957 2761.506504776981 0.4106804037732602 0.2858581769084393 0.4451290826852961 1.3724924991389522 0.852825612370819 1.1887770372503372 1.2133544002566712 1.411309817359306 1.2864722009006833 1.0 11.431239810368524 -5.713735970331692 6.857150946887144 1.1931439427537724 0.3619886609626882 0.8432494497102442 0.15982355986318095 0.0748492596560554 8.197375390927121 0.04473676194362231 0.07714102846297034 1.9331432157631258e-06 5.713735970331692 -0.8311552817910842 FNHDGEEEEEDDDYGSR ddPTM_PC-9_AZD4547_30min_R2 1 FNHDGEEEEEDDDYGSR 17 0 Q6PJT7;Q6PJT7-2;Q6PJT7-9;Q6PJT7-5;H0YJA2;Q6PJT7-11;Q6PJT7-3;Q6PJT7-4;G3V256;Q6PJT7-10;G3V5I6 Q6PJT7 ZC3H14 Zinc finger CCCH domain-containing protein 14 0 175.27 1.3125e-32 0.0 16094.0 19963.0 23766.0 35426.0 23018.0 25542.0 21384.0 34254.0 23078.0 32122.0 False True 21211.557224004195 26415.64935225793 23450.847311571444 27259.083026243967 19822.348019601406 23944.8547022446 23287.134573702893 28960.831378613704 24297.85596532921 30997.418557175853 0.6843007647517071 0.8521886847942939 0.7565419445595288 0.8793984884890852 0.6394838325984589 0.77247899395485 0.7512604486966854 0.9342981682553471 0.783867079786368 1.0 14.919860453441471 -8.794053680641568 0.6642147778967383 0.9994866999630755 0.7661675431602943 0.4157894614342338 0.08060317409345476 1.1150290103222227 0.9980184772550104 0.08322726321404181 0.03108429233308973 1.6067426405273743e-09 8.794053680641568 -0.23331915680278115 FNHDGEEEEEDDDYGSR ddPTM_PC-9_Lapatinib_30min_R1 2 FNHDGEEEEEDDDYGSR 17 0 Q6PJT7;Q6PJT7-2;Q6PJT7-9;Q6PJT7-5;H0YJA2;Q6PJT7-11;Q6PJT7-3;Q6PJT7-4;G3V256;Q6PJT7-10;G3V5I6 Q6PJT7 ZC3H14 Zinc finger CCCH domain-containing protein 14 0 ; 145.79 8.1257e-05 8655900.0 38670.0 38349.0 51939.0 42867.0 37778.0 49562.0 39027.0 40968.0 48959.0 39715.0 False True 38118.558708790515 38260.205246655554 47668.775910337914 46019.58218011999 35555.9723144057 47442.34879466494 41047.62709942241 42871.52284103698 43444.72185887418 46579.68483308893 0.8183515806382643 0.8213925316101871 1.0233812461623897 0.987975387661467 0.7633364725805897 1.0185201760095035 0.8812345391882793 0.9203910029589171 0.9326967757414331 1.0 15.507413257585178 -5.184866281851232 12.400272630002004 0.9340660533530627 0.8196740447445521 0.29746602515518306 0.0738215439885775 1.512079625053352 242.07587485645888 0.01839515079009886 0.04871402343574496 6.5333168081878725e-06 5.184866281851232 -0.11439200860851062 FNHPEQAR ddPTM_PC-9_Lapatinib_30min_R1 2 FNHPEQAR 8 0 A0A087WWA3;Q4R9M9;O60333-2;O60333;O60333-4;O60333-3;O43896;A0A3B3ITK3;A0A3F2YNW9;A0A3B3IUA1;A0A3B3IU40;A0A3B3IT28;A0A3B3ITE5;A0A3B3ITF7;A0A3B3ITW6;Q12756;Q12756-3;Q12756-2 A0A087WWA3;O60333-3;O43896;A0A3B3ITK3 KIF1B;KIF1Bbeta;KIF1C;KIF1A Kinesin-like protein;Kinesin-like protein KIF1B;Kinesin-like protein KIF1C;Kinesin-like protein KIF1A 0 ; 80.165 0.017184 0.0 12897.2 10390.400000000001 12837.0 8718.9 11572.099999999999 10721.599999999999 10853.400000000001 8996.0 12529.5 7797.3 False True 12713.283562943185 10366.34166718427 11781.591412252988 9360.11699139777 10891.451829623957 10263.06216127032 11415.33594590594 9413.987001512613 11118.295768515767 9145.052915750828 1.3901815200048404 1.1335463843331048 1.2883021586415495 1.0235169853721164 1.1909665181778497 1.1222529006468522 1.248252585421887 1.0294076030220218 1.2157716167356842 1.0 13.158775802484131 -1.9083410515654688 1.114632114718342 1.1366998894489893 199.99999855872935 0.38205581418885637 0.09450522120046273 1217.174172313214 2.4988630249644133 0.025857827689398743 617662.7012474972 0.012349772246177872 1.9083410515654688 198.86329866928037 FNISTDRR ddPTM_PC-9_AZD4547_30min_R2 2 FNISTDRR 8 1 O75534;O75534-2;O75534-4;O75534-3;E9PLT0 O75534 CSDE1 Cold shock domain-containing protein E1 0 ; 77.318 0.015004 9497100.0 50137.0 46107.0 65317.0 94280.0 79604.0 64483.0 57762.0 76743.0 49577.0 68195.0 False True 66079.5230856157 61010.186078472994 64450.853902630384 72545.20261147979 68552.35866506012 60450.867816335376 62902.706100178955 64884.13272870174 52197.53900654852 65807.51380694238 1.0041334076146882 0.9271006082596712 0.9793844224492055 1.1023847949081251 1.0417102044938245 0.9186013012690063 0.9558590267475355 0.9859684551987553 0.7931850937216522 1.0 16.00596469775214 -6.770199705081862 24.96518835441331 0.9314168076894408 1.0096116757216838 0.2634896651763319 0.06703592415830369 288.5558196965221 822321.8581285799 0.024201542428505248 0.021665491036775748 1.6974629151114382e-07 6.770199705081862 0.07819486803224296 FNISTDRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FNISTDRR 8 1 O75534;O75534-2;O75534-4;O75534-3;E9PLT0 O75534 CSDE1 Cold shock domain-containing protein E1 0 87.696 0.007296899999999999 4945800.0 11155.0 9068.8 13212.0 13389.0 18890.0 15073.0 14381.0 16363.0 12869.0 9950.7 False True 13043.32117870721 9969.09053038876 13527.024186789025 12638.857737723669 15188.640102999625 14282.545345499993 13018.727570576313 15933.48858803161 13057.184779243924 11754.683140302144 1.1096276286671511 0.8480952154472547 1.1507774412404386 1.0752189222685247 1.2921352214866435 1.2150514969247288 1.107535389528303 1.3555013263949243 1.1108070394918617 1.0 13.520948029720653 -5.597030394813323 2.111182461687323 1.1900937853562188 0.9829414666926244 0.24516302284791758 0.11827970778517419 0.3597175745357071 3.204340346345222 0.03259837090751399 0.07495036096266842 2.529120985561814e-06 5.597030394813323 -0.2071523186635944 FNISTDRR ddPTM_PC-9_Lapatinib_30min_R1 2 FNISTDRR 8 1 O75534;O75534-2;O75534-4;O75534-3;E9PLT0 O75534 CSDE1 Cold shock domain-containing protein E1 0 ; 93.14299999999999 0.0047114 10312500.0 66684.0 59664.0 62590.0 53089.0 60394.0 56266.0 50458.0 44309.0 66583.0 47087.0 False True 65733.07393165206 59525.8516737452 57444.0918043869 56993.34215971234 56841.74365917246 53859.6343424522 53070.46834710984 46367.75789795713 59083.72138992661 55225.92521051637 1.1902575408394402 1.0778606505339274 1.0401653133997317 1.0320033922919123 1.0292583318884516 0.975259973230761 0.9609701991376312 0.8396012872796123 1.0698548039657945 1.0 15.753058063079164 -1.5228808554099598 0.4178338230802693 0.9582926294505353 5.143874753382698 0.5709645095738023 0.05629415920203506 53.50039756211104 0.6882831479845395 0.03802229762805027 186.87076672901776 0.029999854237763742 1.5228808554099598 4.1855821239321624 FNLTYVSHDGDDK ddPTM_PC-9_AZD4547_30min_R2 1 FNLTYVSHDGDDK 13 0 P26639;P26639-2 P26639 TARS Threonine--tRNA ligase, cytoplasmic 0 70.373 0.0238 7440800.0 39920.0 55827.0 60766.0 62493.0 70065.0 72231.0 60605.0 63017.0 49236.0 67029.0 False True 52613.729612417555 73871.9859935131 59960.20313620094 48086.204357225295 60337.68415993452 67714.38415150844 65998.72759255822 53279.170636600116 51838.51444271382 64682.335112039735 0.8134172880630005 1.1420735795260866 0.926995029359108 0.743420970716852 0.9328309507599005 1.0468759984347615 1.020351653635236 0.8237051204832418 0.8014323285163029 1.0 15.981084142370749 -7.776172769251359 24.984027742652376 0.8594265390027738 0.948849737006154 0.06752193515784655 0.11736036375577794 604.829970908851 1025620.1742006228 0.06552810405683568 0.03168772135104153 1.6742766896327834e-08 7.776172769251359 0.08942319800338028 FNLTYVSHDGDDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FNLTYVSHDGDDK 13 0 P26639;P26639-2 P26639 TARS Threonine--tRNA ligase, cytoplasmic 0 ; 118.52 0.00020312 7491700.0 102108.0 123601.0 93805.0 105486.0 115792.0 92301.0 110211.0 93742.0 87271.0 84088.0 False True 119392.86767507294 135871.29042944865 96041.66695744336 99575.96141022604 93103.38881982703 87460.57307337601 99771.01622145783 91281.37182785921 88547.17327448893 99332.48875975836 1.201951840387608 1.3678434128239916 0.9668706397735182 1.0024510877911912 0.9372904070188276 0.8804830540882219 1.0044147435262603 0.9189477981230163 0.891422075295482 1.0 16.599978037953882 -5.272691717280814 24.04747178249523 0.9481866334896405 1.2848976144394626 0.8497490964721829 0.05628462101858247 124.52985919894162 266134.5312144475 0.014246330849773203 0.030135452938082417 5.3371361616744825e-06 5.272691717280814 0.3367109809498221 FNNDSHS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 FNNDSHSPK 9 0 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 FNNDS(0.001)HS(0.999)PK 94.82 0.0056247 3427300.0 17458.0 15756.0 12798.0 21223.0 20991.0 26049.0 19479.0 21183.0 27501.0 25691.0 True False 23009.280851041716 20848.81887462684 12628.290157935357 16330.36524208139 18076.76198103456 24420.15191209652 21212.593264176878 17909.654086914645 28954.646715595773 24791.565909731817 0.9281092180631287 0.8409641791300778 0.5093784799199867 0.6587064851628021 0.7291496651261794 0.9850185341665126 0.8556374914522834 0.7224091512462426 1.1679232695918476 1.0 14.597561778802094 -6.748759010686425 24.307913454602385 0.9231882376194779 0.7226650985738086 0.3333052217956547 0.14843164026401226 216.6308239703368 415273.98526554997 0.050845648078111955 0.05049478643869256 1.7833680810350177e-07 6.748759010686425 -0.20052313904566932 FNNDSHS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 FNNDSHSPK 9 0 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 FNNDS(0.015)HS(0.985)PK;FNNDS(0.003)HS(0.997)PK;FNNDS(0.006)HS(0.994)PK 92.11200000000001 0.0072805000000000005 16925700.0 115243.0 130627.0 108640.0 125402.0 151469.0 132315.0 172230.0 154122.0 158236.0 125654.0 True False 113599.61368702204 130324.54120719891 99708.03856252733 134624.48140880882 142559.8912195119 126656.19589132993 181147.22667213777 161283.0707700233 140413.79538104968 147373.12647656913 0.7708299091088582 0.8843168651098626 0.6765686590653957 0.9134940991444107 0.9673398035847296 0.8594253166737764 1.2291740767333073 1.0943858939958482 0.9527774753653889 1.0 17.16911394708108 -6.508311825222371 1.1767777879019232 1.0627967579368864 0.7923235819535402 0.5281450473124089 0.10188863090875946 0.3660298239644454 1.0649352162059684 0.047025029730528516 0.05415857522617231 3.1023313016436803e-07 6.508311825222371 -0.2704731759833462 FNPFVTSDR ddPTM_PC-9_AZD4547_30min_R2 2 FNPFVTSDR 9 0 J3QRI7;J3QQQ9;J3QQV1;E5RIT6;J3QRC4;Q9UNX3;P61254;E5RHH1;J3KSS0 J3QRI7 RPL26;RPL26L1 60S ribosomal protein L26-like 1;60S ribosomal protein L26 0 ; 125.82 0.0065167 17463100.0 43362.0 45679.0 70487.0 80487.0 72548.0 54121.0 55193.0 66727.0 53128.0 54454.0 False True 57150.21401436993 60443.84344846911 69552.29632461235 61931.96566175409 62475.9624696343 50736.80531439117 60105.070076991404 56415.87538391885 55936.23761703835 52547.58203450765 1.0875897957938343 1.1502687870352633 1.3236060277509596 1.1785883053778532 1.1889407666485348 0.9655402465725758 1.1438218039703674 1.0736150589549662 1.0644873741346537 1.0 15.681336759967497 -6.718417727559039 19.044688047111467 1.0599903027275746 1.1910830235076957 0.47858328659233107 0.07060661000785952 11.852984293175226 5246.331799651261 0.02377488499572123 0.023773120115057663 1.9124155769518225e-07 6.718417727559039 0.13109272078012113 FNPFVTSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FNPFVTSDR 9 0 J3QRI7;J3QQQ9;J3QQV1;E5RIT6;J3QRC4;Q9UNX3;P61254;E5RHH1;J3KSS0 J3QRI7 RPL26;RPL26L1 60S ribosomal protein L26-like 1;60S ribosomal protein L26 0 ; 105.2 0.012221 12629300.0 38622.0 34316.0 45470.0 45421.0 60563.0 51113.0 47959.0 46366.0 39982.0 41356.0 False True 45159.94178072885 37722.66569345677 46554.17724593529 42876.208626868836 48696.11490513318 48432.54430070599 43415.97632690839 45148.94162883783 40566.661111487316 48853.51542608412 0.924394926073566 0.7721586740371132 0.9529340281841588 0.8776483790965051 0.9967781126991958 0.991382992161228 0.8886970763157713 0.9241697600482538 0.8303734287630763 1.0 15.57617475966119 -5.288689247779074 24.96187073866028 0.9308795623071958 0.8482767570733029 0.22329259310352156 0.06294020007303884 928.7418967122182 850759.5693726998 0.016145505848112647 0.03362153867931962 5.144115986238989e-06 5.288689247779074 -0.08260280523389296 FNPFVTSDR ddPTM_PC-9_Lapatinib_30min_R1 2 FNPFVTSDR 9 0 J3QRI7;J3QQQ9;J3QQV1;E5RIT6;J3QRC4;Q9UNX3;P61254;E5RHH1;J3KSS0 J3QRI7 RPL26;RPL26L1 60S ribosomal protein L26-like 1;60S ribosomal protein L26 0 ; 143.7 0.0027168 24419000.0 62681.0 70697.0 64474.0 53991.0 79855.0 51630.0 58513.0 55153.0 55600.0 60715.0 False True 61787.1574457124 70533.30544011085 59173.19659683721 57961.67824869614 75158.08590097055 49421.905255408376 61542.516833692156 57715.609725925424 49337.74250604389 71209.50685234784 0.8676812995465257 0.9905040570827279 0.830973267649953 0.8139598322016057 1.0554501670234853 0.6940352129931776 0.8642457946141927 0.8105042750204425 0.6928533097181137 1.0 16.119782241150535 -6.7755974346857295 24.99996577866918 0.8037291622552287 0.9061746517155059 0.17803710281623453 0.10563705840768313 405.36032102800107 715771.5046172264 0.03554584660479872 0.03149528914194401 1.6764961688634185e-07 6.7755974346857295 0.1024454894602772 FNQAQS(ph)GNIQSTVMLDK ddPTM_PC-9_AZD4547_30min_R2 1 FNQAQSGNIQSTVMLDK 17 0 A0A669KB68;A0A669KB56;A0A669KBA4;A0A669KB53;P42224;J3KPM9;A0A669KBI6;P42224-2;E7ENM1;D2KFR9;A0A669KB17;A0A669KB75;A0A669KB52 A0A669KB68 STAT1 Signal transducer and activator of transcription 1-alpha/beta;Signal transducer and activator of transcription 1 FNQAQS(0.507)GNIQS(0.34)T(0.153)VMLDK 80.69 0.039251999999999995 0.0 8440.5 8607.0 10822.0 12613.0 11937.0 14321.0 12359.0 11834.0 11225.0 15718.0 True False 11124.403426693636 11389.04443094143 10678.493209030818 9705.267718907438 10279.753597618475 13425.505606093682 13458.927057444533 10005.327218266904 11818.330583708313 15167.717604186853 0.7334263280075103 0.7508739764378017 0.704027691422944 0.6398634238963168 0.6777389892056589 0.8851368384118481 0.8873402979054257 0.6596461959118399 0.7791765967772247 1.0 13.888716388743209 -6.750233418987265 24.991641127648208 0.823805395366728 0.7006975565697138 0.38856626897843827 0.0869543467487798 273.17777269688037 609242.7278461203 0.029720147098923733 0.029458852045808837 1.7773239001966432e-07 6.750233418987265 -0.12310783879701426 FNRERIT(ph)Y(ph)CHLPFQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FNRERITYCHLPFQSK 16 2 C9JPK3;C9K0E4;C9JCY1;C9JQS3;E9PFI2;Q9Y2K9 C9JPK3 STXBP5L Syntaxin-binding protein 5-like 2 FNRERIT(0.998)Y(0.964)CHLPFQS(0.038)K 50.155 0.03505 15390000.0 9787.6 11619.0 10504.0 10400.0 11419.0 9307.7 9255.7 7733.1 7075.0 7947.8 True False 11444.447366088278 12772.457532704106 10754.45519664183 9817.321717254921 9181.52892197738 8819.587826730598 8378.933090534958 7530.11431889673 7178.45849041501 9388.673225249817 1.218963222120638 1.360411341013975 1.1454712437662533 1.0456559176915754 0.9779367863485392 0.9393859616938498 0.8924512430575097 0.8020424332849614 0.7645871059937761 1.0 13.196705580283917 -5.935539485948129 0.8378117395309216 0.8509081366662872 1.3258943033355206 0.8269875015240912 0.07314809998050557 0.2773343392823574 0.3807762204233696 0.03437224953612856 0.08923157850037851 1.1600067438237884e-06 5.935539485948129 0.47498616666923343 FNS(ph)LPRPDPEPVPPVGSK ddPTM_PC-9_AZD4547_30min_R2 1 FNSLPRPDPEPVPPVGSK 18 1 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 FNS(1)LPRPDPEPVPPVGSK 59.501999999999995 0.013543000000000001 4648600.0 13327.0 11136.0 15508.0 22294.0 24330.0 17538.0 16505.0 24212.0 20635.0 20571.0 True False 17564.708781179565 14735.494223650969 15302.353787252812 17154.462738866452 20952.199466369893 16441.346087540747 17973.913025578284 20470.59173641021 21725.723972812557 19850.815551325093 0.884835624801676 0.7423117798637415 0.7708677634774225 0.8641691669802124 1.055483056209813 0.8282453708277615 0.905449601257238 1.031221698850743 1.0944499442171438 1.0 14.276910659848786 -6.708810377469928 0.5349214635246149 1.0445847970314446 0.779095790076368 0.5117331511728721 0.08097904694494115 0.8473302888476634 0.521244379060517 0.07453683786747503 0.09803704101317767 1.9551929497123903e-07 6.708810377469928 -0.2654890069550766 FNS(ph)LPRPDPEPVPPVGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FNSLPRPDPEPVPPVGSK 18 1 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 FNS(1)LPRPDPEPVPPVGSK 67.645 0.0060252 5388400.0 20208.0 23280.0 16026.0 25315.0 30194.0 28249.0 32037.0 33275.0 20788.0 22743.0 True False 23628.81527380686 25591.084547839888 16408.12061894346 23896.682622337357 24277.702449442575 26767.57271047765 29002.22343220592 32401.566507776784 21091.985172967805 26866.12586651107 0.8795021430038206 0.9525409310964134 0.6107363860524591 0.8894725924039849 0.9036547572981115 0.9963316945463928 1.0795089540006033 1.2060379181118073 0.7850772857153626 1.0 14.713500677225886 -6.603780007102009 2.052914615457883 1.034340004549364 0.8262399868050865 0.3066373334495833 0.12796688673412296 0.3747177941895355 3.2172008300907406 0.0482722290396979 0.049380763816239986 2.490118374217752e-07 6.603780007102009 -0.20810001774427755 FNS(ph)LPRPDPEPVPPVGSK ddPTM_PC-9_Lapatinib_30min_R1 1 FNSLPRPDPEPVPPVGSK 18 1 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 FNS(1)LPRPDPEPVPPVGSK 62.442 0.0097867 4906600.0 23208.0 18694.0 21751.0 17503.0 23926.0 24561.0 28520.0 23232.0 25490.0 30292.0 True False 22877.049664174043 18650.715191555933 19962.71674128806 18790.229008296352 22518.719720325866 23510.583284487417 29996.62605056826 24311.443532585716 22619.04777840035 35527.93183844716 0.6439172921238621 0.5249592145235075 0.5618879486726852 0.5288860914769652 0.6338314265722849 0.6617492791698343 0.8443110673306036 0.6842909866843605 0.6366553471576625 1.0 15.11666608810997 -6.836519865131509 2.0092281791479434 0.7648791629127333 0.5642049674270605 0.49973877462644967 0.09883198014134968 0.29536963016228457 2.448769413014597 0.03961402587601535 0.03453779688155262 1.4570690551836256e-07 6.836519865131509 -0.20067419548567278 FNSLPQYS(ph)PVTFDR ddPTM_PC-9_Lapatinib_30min_R1 1 FNSLPQYSPVTFDR 14 0 C9JA69;Q8WY36-2;Q8WY36 C9JA69 BBX HMG box transcription factor BBX 1 FNS(0.002)LPQY(0.082)S(0.902)PVT(0.015)FDR 82.57799999999999 0.042041 0.0 47575.0 36944.0 37103.0 26972.0 28110.0 27341.0 32516.0 29049.0 28513.0 25219.0 True False 46896.571775813536 36858.4584378326 34052.534561721804 28955.610855954357 26456.62506638637 26171.68916498393 34199.51937799011 30398.72258858826 25301.565684799087 29578.070547794767 1.5855182879503265 1.2461414066300764 1.1512763994087045 0.9789553652313262 0.8944675760251332 0.8848342261775827 1.1562457842788498 1.027745286477271 0.8554163681472955 1.0 14.852240324416547 -4.663569103699518 1.049996923078235 0.9725729147460218 2.0010771251012573 0.8295843318443377 0.08622763020941507 0.9209236672920261 0.7038089733448039 0.02954353286368274 1.1268594865572605 2.1698559148128373e-05 4.663569103699518 1.0285042103552355 FNSLPQYS(ph)PVTFDRK ddPTM_PC-9_Lapatinib_30min_R1 2 FNSLPQYSPVTFDRK 15 1 C9JA69;Q8WY36-2;Q8WY36 C9JA69 BBX HMG box transcription factor BBX 1 FNS(0.005)LPQY(0.002)S(0.528)PVT(0.465)FDRK;FNSLPQY(0.441)S(0.558)PVT(0.001)FDRK 67.234 0.013865 7510900.0 41339.0 32878.0 29167.4 27681.0 26697.0 24171.0 23566.8 23695.0 25277.0 19776.0 True False 40749.49827935584 32801.873011018295 26769.368961419947 29716.753081109033 25126.73494832148 23137.262675352995 24786.973590761994 24795.956202850324 22430.038081389772 23194.255250136383 1.7568789271264156 1.4142240247539493 1.1541378963337288 1.2812117811342227 1.083317169589816 0.9975428150561958 1.0686686562447936 1.069055933697398 0.967051446122974 1.0 14.501479902642368 -1.5228787452816461 0.5082136458154459 1.0177835790816554 25.970283767604077 0.9328958583023619 0.06039937114619261 26.064094155686757 0.2706765995803888 0.03323294940096444 697.1447665989602 0.029999999999909606 1.5228787452816461 24.95250018852242 FNVWDTAGQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FNVWDTAGQEK 11 0 F5H018;B5MDF5;J3KQE5;P62826;H0YFC6 F5H018 RAN GTP-binding nuclear protein Ran 0 112.15 0.007942399999999999 3757300.0 30454.0 22650.0 21484.0 32624.0 30343.0 25477.0 28028.0 33063.0 29427.0 22698.0 False True 35609.26070608243 24898.542311364836 21996.260038523717 30796.18304843506 24397.506969048038 24140.941270304742 25372.984934852455 32195.13128314421 29857.314204585484 26812.967722730853 1.3280611484082185 0.92860076396008 0.8203590242596032 1.1485555559121272 0.9099144571141562 0.9003457401635968 0.9462952850736607 1.2007298713096421 1.1135400793129575 1.0 14.71064328860933 -10.834989621823414 4.685791640678951 0.9999869145999528 1.021882543362808 0.0 0.1524839534220328 2.1066739213954098e-05 3.0927990932586087e-06 0.1492131790327233 0.0361678836656148 1.462212115988012e-11 10.834989621823414 0.021895628762855224 FNVWDTAGQEK ddPTM_PC-9_Lapatinib_30min_R1 2 FNVWDTAGQEK 11 0 F5H018;B5MDF5;J3KQE5;P62826;H0YFC6 F5H018 RAN GTP-binding nuclear protein Ran 0 ; 152.67 0.0018210000000000001 30444000.0 111739.0 115537.0 137022.0 119451.0 110388.0 107696.0 117685.0 118121.0 117928.0 115736.0 False True 110145.58136957712 115269.48117507223 125756.58008021602 128235.82501685474 103895.19487115825 103090.09313163775 123778.15346287252 123609.33288191131 104645.70680310694 135740.81339147373 0.8114404107180315 0.8491880834884745 0.9264463423947271 0.9447108928618635 0.7653939318274647 0.7594627625688969 0.9118713109954547 0.9106276129746219 0.7709229390081144 1.0 17.050495037674295 -11.410289467575597 3.423988678906704 1.0603155828416506 0.8534674646347548 0.3067274711507394 0.06746968792915352 7580178.592328646 30271609.66313319 3131255.9097164976 0.017176492915075975 3.887859235734606e-12 11.410289467575597 -0.20684811820689586 FNYSGS(ph)GGR ddPTM_PC-9_AZD4547_30min_R2 4 FNYSGSGGR 9 0 Q12906-7;Q12906 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 FNYS(0.128)GS(0.872)GGR;FNYSGS(1)GGR;FNYS(0.068)GS(0.932)GGR;FNYS(0.029)GS(0.971)GGR 100.69 0.0037398 40771300.0 69454.0 74284.0 88161.0 114342.0 93878.0 92209.0 75378.0 96312.0 64566.0 91431.0 True False 91538.92726705527 98294.85029720618 86991.92753662587 87982.21846628985 80844.66015223495 86443.1566533267 82086.4959734649 81429.19342958619 67978.82694589853 88230.02851943049 1.0375030905367562 1.1140747877641133 0.9859673514382695 0.9971913184513358 0.9162941632103282 0.979747576918098 0.9303691424670386 0.9229192690519579 0.7704726847155883 1.0 16.428982130831685 -5.820777030588111 0.6548037256571517 0.9005079186051202 1.1002767923214412 0.4795440837807873 0.061882883343223866 0.9738431267126997 0.7228660758783019 0.0350742902886264 0.12244485638176687 1.5108556374941143e-06 5.820777030588111 0.1997688737163209 FNYSGS(ph)GGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FNYSGSGGR 9 0 Q12906-7;Q12906 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 FNYS(0.002)GS(0.998)GGR;FNYS(0.026)GS(0.974)GGR 85.92399999999999 0.01206 11484100.0 34780.0 39393.0 40087.0 35037.0 40465.0 34459.0 38112.0 29847.0 28604.0 25899.0 True False 40667.56706368778 43303.67670073266 41042.826110794114 33073.9904814866 32536.17373043302 32651.909378397453 34501.755453014695 29063.547875510547 29022.27938654852 30594.283683628804 1.3292537744705966 1.4154172442319588 1.3415194333429155 1.0810513108755904 1.063472316164844 1.0672552335608267 1.1277190147608132 0.9499666073588328 0.9486177119446181 1.0 14.90097450071348 -5.778355690007874 3.36996532045533 1.0332226536484528 1.3764393365363605 0.8840831934935738 0.05477393762141637 0.07812867854779049 1.8477506490746238 0.017169472804285622 0.02905539684306251 1.6658822852489095e-06 5.778355690007874 0.34321668288790774 FNYSGS(ph)GGR ddPTM_PC-9_Lapatinib_30min_R1 1 FNYSGSGGR 9 0 Q12906-7;Q12906 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 FNYS(0.006)GS(0.994)GGR 89.561 0.0092508 9922400.0 19338.0 16007.0 20352.0 13147.0 16218.0 15123.0 14911.0 13240.0 17979.0 13541.0 True False 19062.23657384512 15969.936774967155 18678.737120991882 14113.87423710634 15264.089125814804 14476.224543434842 15683.01861991666 13855.178734996327 15954.015692736739 15881.543807751648 1.2002760439788607 1.0055657666713964 1.17612855192799 0.8886966158930643 0.9611212430346053 0.9115124271715398 0.9874996291142621 0.8724075507214689 1.0045632770883217 1.0 13.955063539859747 -5.762965367550634 24.99999992988147 0.9420809552897665 1.1151476962330518 0.622323866650363 0.06426234763288888 24.52223600794277 401756.7267333776 0.016361766998606482 0.025812015292437335 1.7259755229735953e-06 5.762965367550634 0.17306674094328522 FPAT(ph)SPLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FPATSPLK 8 0 Q5TB30;H0YES2;Q5TB30-2 Q5TB30 DEPDC1 DEP domain-containing protein 1A 1 FPAT(0.5)S(0.5)PLK 89.029 0.025751999999999997 8032100.0 71457.0 78654.0 71612.0 90134.0 91143.0 79483.0 88431.0 77060.0 64492.0 61929.0 True False 83553.25875991772 86462.24931382312 73319.50167002247 85084.08419837062 73284.18342550006 75314.77155817524 80054.17549500268 75037.25665181896 65435.073493122894 73156.23747030561 1.1421207766983956 1.1818848577186392 1.002231719472767 1.163046202764413 1.0017489411650835 1.0295058106117854 1.0942904974780443 1.0257123554539946 0.894456518757997 1.0 16.158693256679292 -4.8138854642358915 0.27837801987106586 0.968068895187233 1.3116809034748929 0.4491913635807242 0.06332893451864381 8.098223104697874 0.5303231473603575 0.07960522795298616 0.9570389746294654 1.535021758166408e-05 4.8138854642358915 0.3436120082876598 FPDENFK ddPTM_PC-9_Lapatinib_30min_R1 1 FPDENFK 7 0 P23284 P23284 PPIB Peptidyl-prolyl cis-trans isomerase B 0 85.064 0.036177999999999995 0.0 30389.0 36640.0 28924.0 29361.0 25502.0 26319.0 25725.0 22844.0 26836.0 26042.0 False True 29955.64728733994 36555.16233115491 26545.980369868776 31520.305885424765 24002.022498861086 25193.397722585563 27056.914626608275 23905.415636122074 23813.447084391988 30543.325001216203 0.9807592096193567 1.1968298254921272 0.8691254265477562 1.0319867232585076 0.7858352847276893 0.8248413596614772 0.8858536071475813 0.782672339542934 0.779661254412994 1.0 14.898569504606712 -5.7813841484166115 1.263309151555955 0.8353072757230294 1.0779490340280733 0.40842801829278386 0.09976306002626456 0.4194305447541504 1.3289937440369082 0.0329857221337758 0.08207885073226777 1.6543060254964428e-06 5.7813841484166115 0.24264175830504386 FPDSVEELR ddPTM_PC-9_Lapatinib_30min_R1 1 FPDSVEELR 9 0 Q15785 Q15785 TOMM34 Mitochondrial import receptor subunit TOM34 0 90.709 0.038537 1145900.0 5060.9 6797.3 6942.7 5154.8 7133.0 6431.8 5625.1 5750.0 7183.8 5321.7 False True 4988.730637944607 6781.561269474863 6371.898005597009 5533.901187908704 6713.4509640175675 6156.726907258097 5916.34015417432 6017.165991407015 6374.684795232341 6241.548754280482 0.7992776848091291 1.0865189933546602 1.0208841197030036 0.8866230811885479 1.0756065887354405 0.9864101282611605 0.9478961692187162 0.9640501465730626 1.0213306097882442 1.0 12.607688343057585 -4.743920094871845 24.99645722597859 0.995294673572596 0.7992770863514957 0.5334796398723327 0.05589097698416632 907.092067613825 1294167.6225089086 0.013835166032570916 0.41933405698599335 1.8033495056507444e-05 4.743920094871845 -0.1960175872211003 FPEAEALS(ph)PEQAAHYLR ddPTM_PC-9_AZD4547_30min_R2 2 FPEAEALSPEQAAHYLR 17 0 Q2NKX8 Q2NKX8 ERCC6L DNA excision repair protein ERCC-6-like 1 FPEAEALS(1)PEQAAHYLR;FPEAEALS(1)PEQAAHYLR 142.93 1.9546e-05 11266200.0 24826.0 27715.0 25940.0 26406.0 26181.0 29449.0 28227.0 33292.0 26144.0 27258.0 True False 32720.151587121163 36673.33175363563 25596.01865110508 20318.50466863314 22546.220066955633 27607.549374614395 30739.148317055344 28147.486374052893 27525.918465966155 26303.70571668948 1.2439369547219539 1.394226811561639 0.9730955374422632 0.7724578767523703 0.857149951029533 1.0495688201490803 1.168624248162555 1.0700958517869041 1.0464654205928554 1.0 14.682978443039664 -5.267640002448306 24.92205565061267 0.9903667713809201 1.3190818908866722 0.5841519896671343 0.11031773816945652 333.880319892838 1341963.483375572 0.03322791068905323 0.07203263616911834 5.399580217603534e-06 5.267640002448306 0.32871511950575205 FPEAEALS(ph)PEQAAHYLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FPEAEALSPEQAAHYLR 17 0 Q2NKX8 Q2NKX8 ERCC6L DNA excision repair protein ERCC-6-like 1 FPEAEALS(1)PEQAAHYLR;FPEAEALS(1)PEQAAHYLR 123.43 2.5366e-05 7927200.0 28858.0 41663.0 34257.0 29091.0 35166.0 24119.3 33333.0 21502.8 26573.0 23246.0 True False 33743.089428519284 45799.0272988253 35073.81680039598 27461.125584294532 28275.474741243237 22854.441448399008 30175.45692997845 20938.374284099853 26961.579853823026 27460.31578476526 1.2287946611029015 1.6678259513765021 1.2772546781801624 1.000029489811247 1.0296849811512445 0.8322716179789328 1.098875088199806 0.762495757449238 0.9818379389788764 1.0 14.745060595657016 -5.675009649473643 2.938909396139069 0.9462751811746889 1.4552980328804708 0.6941842286619127 0.1347180843476331 0.12495658358807979 2.163374907975666 0.03606119812062354 0.06788683800027057 2.11344208130719e-06 5.675009649473643 0.5090228517057819 FPEAEALS(ph)PEQAAHYLR ddPTM_PC-9_Lapatinib_30min_R1 2 FPEAEALSPEQAAHYLR 17 0 Q2NKX8 Q2NKX8 ERCC6L DNA excision repair protein ERCC-6-like 1 FPEAEALS(1)PEQAAHYLR;FPEAEALS(1)PEQAAHYLR 158.02 1.604e-05 8759600.0 21311.0 42502.0 31744.0 30260.0 36466.0 32916.0 37754.0 32736.0 33929.0 29940.0 True False 21007.10123204123 42403.589230315105 29134.130855383566 32485.421344400835 34321.14157491442 31508.259410943694 39708.717388259254 34257.03406864352 30107.558731790723 35115.08910745771 0.5982357375701423 1.20756034821821 0.8296755496256476 0.9251128836663443 0.9773901319141273 0.8972854750424655 1.1308163640634463 0.9755644920567224 0.8573966205711979 1.0 15.099803475683773 -4.735914129680446 24.98145585377833 0.9730703098184476 0.5982339386388514 0.5136757303340973 0.1107272530757472 2079.0927086124234 2034692.7199875766 0.026447401815796214 1.9985156790859242 1.836901506439152e-05 4.735914129680446 -0.3748363711795961 FPEFCSSPS(ph)PPVEVK ddPTM_PC-9_AZD4547_30min_R2 2 FPEFCSSPSPPVEVK 15 0 Q68E01-4;Q68E01-3;Q68E01-2;Q68E01 Q68E01-4 INTS3 Integrator complex subunit 3 1 FPEFCS(0.026)S(0.062)PS(0.912)PPVEVK;FPEFCS(0.015)S(0.042)PS(0.943)PPVEVK 154.46 0.00017514 15782900.0 37565.0 45942.0 53214.0 52332.0 56283.0 54439.0 45246.0 56751.0 44902.0 51299.0 True False 49509.88859946052 60791.85305522382 52508.34759059005 40267.66592134023 48469.07696529784 51034.92072412076 49272.80634688372 47981.436958244514 47275.4280507502 49503.037624200355 1.0001383950478389 1.2280428832816666 1.0607096071397546 0.8134382828591257 0.9791131876239239 1.0309452343419734 0.9953491484893427 0.9692624788501467 0.9550005478378734 1.0 15.59522943465909 -5.530817282842751 24.944934818735778 0.9645440106760905 1.121662063608263 0.41063312982905287 0.07473863160022687 148.6048578130476 466953.5329642524 0.019836980819786066 0.034442714339032524 2.945660676803827e-06 5.530817282842751 0.15711805293217251 FPEFCSSPS(ph)PPVEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FPEFCSSPSPPVEVK 15 0 Q68E01-4;Q68E01-3;Q68E01-2;Q68E01 Q68E01-4 INTS3 Integrator complex subunit 3 1 FPEFCS(0.004)S(0.033)PS(0.962)PPVEVK 117.0 0.00013555 4576600.0 14902.0 17082.0 14951.0 17030.0 19118.0 15793.0 14956.0 14869.0 15356.0 12880.0 True False 17424.61427208381 18777.78806899489 15307.488541983246 16075.864312004938 15371.965139711307 14964.787278012442 13539.25940793681 14478.704505007754 15580.552449302168 15215.042041976101 1.1452228803582547 1.234159459907484 1.0060759937272667 1.0565770549732267 1.0103136815069111 0.9835521477184721 0.8898601377889033 0.9516046334320406 1.0240229640061247 1.0 13.893210699840777 -5.468738833000106 1.0133310383086778 0.9670969130768184 1.2161956306015997 0.6809348444543177 0.052230814556912544 0.44364691685992136 0.7241532053260303 0.019147736759387843 0.09466091611494777 3.398295708086225e-06 5.468738833000106 0.2490987175247813 FPEFCSSPS(ph)PPVEVK ddPTM_PC-9_Lapatinib_30min_R1 2 FPEFCSSPSPPVEVK 15 0 Q68E01-4;Q68E01-3;Q68E01-2;Q68E01 Q68E01-4 INTS3 Integrator complex subunit 3 1 FPEFCS(0.103)S(0.075)PS(0.822)PPVEVK;FPEFCS(0.061)S(0.08)PS(0.859)PPVEVK 110.32 0.00053921 8832800.0 34446.0 41263.0 38554.0 41233.0 40412.0 43424.0 37587.0 31805.0 44168.0 31125.0 True False 33954.793723377246 41167.458058691176 35384.23894274378 44265.41236925579 38035.04561304893 41566.85674628809 39533.07094539653 33282.77640986091 39193.33473034075 36504.91477854445 0.9301430760587333 1.1277237135994387 0.9693006861514619 1.2125877470962492 1.0419157487090973 1.1386646701807606 1.082952013043237 0.911734121604433 1.073645424680635 1.0 15.155803091468162 -10.959310532987733 4.759539389941002 0.9998807587275859 1.0573788324634448 0.030376972808803915 0.09053307285754801 0.0001109974661888759 1.3142982310311162e-05 0.08493863445888665 0.020557955677123183 1.0982202996696867e-11 10.959310532987733 0.05749807373585891 FPNRGS(ph)RNFPR ddPTM_PC-9_AZD4547_30min_R2 1 FPNRGSRNFPR 11 2 A6NEH8 A6NEH8 ZNF503-AS2 Putative uncharacterized protein encoded by ZNF503-AS2 1 FPNRGS(1)RNFPR 47.228 0.041055 3618800.0 1188.8 942.11 4535.5 4722.8 4194.7 3711.0 3932.0 5071.4 3550.5 5521.6 True False 1566.8136714238965 1246.6286335348243 4475.356306556943 3634.031426532633 3612.3383107925133 3478.950583354072 4281.940382706685 4287.731659178537 3738.1721815105884 5328.29046464424 0.29405560410425363 0.23396409069790816 0.8399234869519738 0.6820257736784757 0.6779544649005358 0.652920595534079 0.8036236783860435 0.8047105704221064 0.7015706456536391 1.0 12.379457015809919 -5.257452360953098 24.998557589015817 0.753907958986409 0.26400979268628777 0.805236409868246 0.09934368165956331 131.5894358197073 825055.6503517986 0.02457531818042005 0.06021835080862471 5.5277404003916024e-06 5.257452360953098 -0.4898981663001213 FPPEDFRHS(ph)PEDFR ddPTM_PC-9_AZD4547_30min_R2 4 FPPEDFRHSPEDFR 14 1 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 1 FPPEDFRHS(1)PEDFR;FPPEDFRHS(1)PEDFR;FPPEDFRHS(1)PEDFR;FPPEDFRHS(1)PEDFR 68.329 0.015222999999999999 48794200.0 57347.0 61356.0 76556.0 91471.0 89389.0 81472.0 63805.0 80658.0 68834.0 72797.0 True False 75582.15310829927 81188.12711802521 75540.81741919815 70383.77416286236 76978.88031645451 76377.5429606638 69483.52139333668 68194.15943645188 72472.42471260378 70248.39918768225 1.0759270528907976 1.155729213147126 1.075338631096435 1.0019270898233343 1.0958097438034207 1.0872495863799878 0.9891118117538585 0.9707574866476022 1.0316594477687613 1.0 16.100177729291467 -6.476853598750268 0.48127476318368717 0.9893442965252243 1.121076720144878 0.44949473367496473 0.04136782024697138 1.181064481462392 0.5542376641286226 0.03913437470236317 0.07124152167036156 3.335388301991471e-07 6.476853598750268 0.13173242361965365 FPPEDFRHS(ph)PEDFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FPPEDFRHSPEDFR 14 1 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 1 FPPEDFRHS(1)PEDFR;FPPEDFRHS(1)PEDFR;FPPEDFRHS(1)PEDFR 68.97800000000001 0.012965 17607500.0 31891.1 34089.5 43091.8 39892.6 49782.3 32314.2 37807.1 34800.8 34734.2 32256.3 True False 37289.633352063596 37473.68027034311 44119.271938561564 37657.54695555421 40027.81568023071 30619.586466102057 34225.737788299535 33887.315874495514 35242.12196434951 38104.11184926969 0.9786249184752562 0.9834550249741967 1.1578611807850643 0.9882804014568826 1.0504854656781062 0.8035769626969776 0.8982163899709293 0.8893348835565368 0.9248902612861968 1.0 15.217659068198945 -6.739995978112228 24.98165956924924 0.8959754101392243 1.0336510191017991 0.4850093700964424 0.0660010352657905 193.23986691985115 225124.8642434197 0.02147854184235512 0.021459535008736062 1.8197177104624128e-07 6.739995978112228 0.1376756089625748 FPPEDFRHS(ph)PEDFR ddPTM_PC-9_Lapatinib_30min_R1 5 FPPEDFRHSPEDFR 14 1 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 1 FPPEDFRHS(1)PEDFR;FPPEDFRHS(1)PEDFR;FPPEDFRHS(1)PEDFR;FPPEDFRHS(1)PEDFR;FPPEDFRHS(1)PEDFR 70.134 0.013259 60478000.0 68551.9 88760.0 93544.3 79596.4 95377.0 96764.7 76091.9 75343.8 97836.4 78995.0 True False 67574.33733512112 88554.4816733981 85853.44874544024 85450.1847818065 89767.1123783968 92626.29935053283 80031.56626147391 78844.54800406467 86817.03436903445 92649.18049577871 0.7293570971002808 0.9558042629144768 0.9266509243365828 0.9222983336123496 0.9688926755535283 0.9997530345641112 0.8638129968685511 0.8510010297139864 0.9370512928928714 1.0 16.499490594874793 -4.757242847979603 24.999654396234316 0.9315063392127078 0.7293568010981252 0.6294628590274296 0.047476026588659716 88.12873571073197 524932.9634049666 0.012453211083505859 0.09404578277013959 1.7488684861322695e-05 4.757242847979603 -0.20214953811458258 FPQGPPS(ph)QMGSPMGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FPQGPPSQMGSPMGSR 16 0 Q8WXF1 Q8WXF1 PSPC1 Paraspeckle component 1 1 FPQGPPS(0.888)QMGS(0.108)PMGS(0.003)R 74.783 0.0076968 6172600.0 6365.4 11171.0 8627.1 8387.8 9338.3 6649.7 7346.4 4975.1 4016.0 6593.1 True False 7442.936497619259 12279.983053432967 8832.802782458946 7917.858759614505 7508.527150547448 6300.978025872176 6650.495808669897 4844.508896554179 4074.726402474441 7788.376839049113 0.9556466836969295 1.5767063288288752 1.1341005918169398 1.0166250199805689 0.9640682912133163 0.8090232606979846 0.8539001060305473 0.6220177832516958 0.5231804375521109 1.0 12.927106974918885 -6.304860423261002 0.9537789795862754 0.7127858617579654 1.2773400244380495 0.526193055125191 0.18882000585627168 0.4072583722596011 0.7906631348748288 0.08945295753552938 0.13504627573304423 4.95609447803305e-07 6.304860423261002 0.5645541626800841 FPQGPPSQMGS(ph)PMGSR ddPTM_PC-9_AZD4547_30min_R2 1 FPQGPPSQMGSPMGSR 16 0 Q8WXF1 Q8WXF1 PSPC1 Paraspeckle component 1 1 FPQGPPS(0.097)QMGS(0.898)PMGS(0.005)R 68.329 0.014003 7451300.0 7626.5 9099.1 9652.6 8718.5 9163.5 10481.0 10223.0 11372.0 7396.4 7024.7 True False 10051.568358945447 12040.20613240144 9524.600217103198 6708.584524482241 7891.30619852366 9825.621413132314 11132.827195424828 9614.71870256306 7787.358603950127 6778.767391152272 1.4828017807580882 1.776164520428369 1.4050637331994633 0.9896466624947724 1.1641211068583777 1.4494702128231798 1.6423084836862123 1.4183579621145144 1.1487868154488206 1.0 12.726807251189232 -13.92180105217897 0.10020866735025595 1.3674801739882428e-24 1.6458998278604673 0.2606677117095727 0.21575650948248534 283.12177106689217 2.1846509189025753 63.22171108857542 4.331105254372727 1.1972888768950407e-14 13.92180105217897 1.6458998278604673 FPQGPPSQMGS(ph)PMGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FPQGPPSQMGSPMGSR 16 0 Q8WXF1 Q8WXF1 PSPC1 Paraspeckle component 1 1 FPQGPPS(0.079)QMGS(0.92)PMGS(0.002)R 66.538 0.015867 5723500.0 10092.0 20504.0 14820.0 14950.0 17658.0 11652.0 15208.0 10738.0 8300.9 10494.0 True False 11800.376273914222 22539.501613784756 15173.365005162977 14112.399968553958 14198.041659013621 11040.948607826307 13767.388143614811 10456.13887785145 8422.284958740056 12396.47912954171 0.9519135353354541 1.81821800998894 1.2240060138530582 1.1384200159642976 1.145328565526211 0.8906519740363152 1.1105885792044068 0.843476503980369 0.6794094412395806 1.0 13.597642801481607 -6.347863531851503 0.8767874727543016 0.870429803052731 1.3944630438729804 0.39403547437024433 0.22687065579001256 0.5767978477088676 0.9615310886715752 0.11636218960019631 0.17244613922367455 4.48886421140511e-07 6.347863531851503 0.5240332408202494 FPQGPPSQMGS(ph)PMGSR ddPTM_PC-9_Lapatinib_30min_R1 1 FPQGPPSQMGSPMGSR 16 0 Q8WXF1 Q8WXF1 PSPC1 Paraspeckle component 1 1 FPQGPPS(0.063)QMGS(0.924)PMGS(0.013)R 57.567 0.034086 4264100.0 9021.2 16092.0 15629.0 13798.0 18076.0 15105.0 20643.0 17736.0 14093.0 16687.0 True False 8892.55603371453 16054.739962689535 14344.043949684665 14812.750948778685 17012.805218783345 14458.994361474795 21711.793533025255 18560.07930845128 12505.697934130872 19571.32571597016 0.4543665647778895 0.820319491672907 0.7329112068264213 0.7568598654863483 0.8692719882997467 0.738784616398075 1.109367543523558 0.9483302039833865 0.6389806247987713 1.0 14.256453863622324 -4.142502252290666 0.5642120309363667 0.893812135761482 5.912942991099434e-19 0.41888271471531613 0.13592700912802969 8.165446103703317 1.1612889412140788 0.0703224798730995 5.590059870608597 7.202740158221265e-05 4.142502252290666 -0.893812135761482 FPTTATKIS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FPTTATKISPK 11 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 FPTTATKIS(1)PK 100.11 0.020664 7262400.0 21137.0 15612.0 13120.0 22037.0 21896.0 13340.0 21998.0 18729.0 20040.0 18557.0 True False 24715.07662522047 17161.856183886444 13432.830557877076 20802.33833491796 17605.635981751177 12640.426916272138 19914.19018827187 18237.38359501582 20333.04708804478 21921.237202868826 1.1274489845849582 0.7828872077366362 0.6127770268422225 0.9489582245018344 0.8031314938486744 0.576629265916519 0.9084428038425544 0.831950470050527 0.9275501605987732 1.0 14.42004160376366 -8.369415565500177 1.5073460689306417 0.9986236913040878 0.8080771677703492 0.1292563306439335 0.14950407692854048 0.7656556899573863 3.589211016817712 0.1417265432075324 0.042528726121776494 4.271539576245241e-09 8.369415565500177 -0.19054652353373858 FPTTATKIS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 FPTTATKISPK 11 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 FPTTATKIS(1)PK 131.66 0.00071118 6337000.0 29726.0 22681.0 17774.0 16100.0 16495.0 15982.0 15125.0 15982.0 16276.0 15639.0 True False 29302.101788919244 22628.483538016477 16312.690329624105 17284.047708025555 15524.796530417747 15298.487115861646 15908.098492806623 16724.582065159477 14442.825486121774 18342.180312342374 1.5975255553017318 1.2336855898635926 0.8893539400355456 0.9423115144274966 0.8463986432393306 0.8340604473050218 0.867295938755009 0.9118099255575183 0.7874105062855182 1.0 14.162877520055162 -4.884029478993929 1.6667052031574736 0.8726501353178668 1.773587756377962 0.9384635682642625 0.058076711719804636 0.15672625932273737 0.5060898628456392 0.015300546751958442 0.21545208285635156 1.3060822310143562e-05 4.884029478993929 0.9009376210600952 FPVFNPATEEELCQVEEGDKEDVDK ddPTM_PC-9_Lapatinib_30min_R1 2 FPVFNPATEEELCQVEEGDKEDVDK 25 1 P00352;Q5SYQ7;Q5SYQ9;Q5SYQ8 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ; 133.94 8.1052e-09 5756300.0 14803.0 15555.800000000001 15677.300000000001 11821.9 12217.5 6805.1 15430.5 12462.0 11508.5 18366.5 False True 14591.90650546227 15519.781500845504 14388.372910128053 12691.321962702319 11498.890670529176 6514.061736462904 16229.415787983651 13041.030014767692 10212.29154012242 21541.125053177086 0.6773976043238336 0.7204721880836258 0.6679489986993935 0.5891670899905241 0.533811054071812 0.3024011847283784 0.7534154204072079 0.6054015276627476 0.4740834805476521 1.0 14.394805980696779 -12.681264121874355 16.958482305503356 0.9897261890899277 0.6151365062430753 0.0 0.17609217002233088 0.0 0.0 0.0 0.03896795916176705 2.083223558088658e-13 12.681264121874355 -0.37458968284685246 FPVPHNGSSEATLPAQMS(ph)TLHVSPPPSADPAR ddPTM_PC-9_AZD4547_30min_R2 1 FPVPHNGSSEATLPAQMSTLHVSPPPSADPAR 32 0 P50479;P50479-2;C9J542 P50479 PDLIM4 PDZ and LIM domain protein 4 1 FPVPHNGSSEATLPAQMS(0.452)T(0.452)LHVS(0.081)PPPS(0.015)ADPAR 63.095 0.00020846 5016500.0 8914.5 5058.4 27832.0 53321.0 39535.0 31188.0 19148.0 48663.0 23625.0 27561.0 True False 11749.12556688116 6693.428877596627 27462.92949489426 41028.6672512379 34046.24767377451 29237.809429708086 20852.134905408857 41143.25151449402 24873.769268606575 26596.097778915515 0.44176125627705687 0.2516695845096099 1.03259243980769 1.5426574075751833 1.280121917011646 1.0993270393556318 0.7840298632809104 1.5469657186743762 0.9352413077803337 1.0 14.69892696632903 -5.33365479304548 4.719919439717591 1.1838698206196232 0.3459062617589448 0.6518628926242009 0.2363646649174379 0.11557188823877593 4.8522872264070225 0.06219275932189352 0.13811017509486984 4.638154454873907e-06 5.33365479304548 -0.8379635588606784 FPVPHNGSSEATLPAQMS(ph)TLHVSPPPSADPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FPVPHNGSSEATLPAQMSTLHVSPPPSADPAR 32 0 P50479;P50479-2;C9J542 P50479 PDLIM4 PDZ and LIM domain protein 4 1 FPVPHNGSSEATLPAQMS(0.923)T(0.074)LHVS(0.001)PPPSADPAR 76.73100000000001 4.2552e-07 3957900.0 1384.3 4622.0 5708.2 4517.5 4284.3 6102.8 4722.6 4033.2 4336.5 3978.8 True False 1618.634648828723 5080.841614266152 5844.305136469053 4264.399120932606 3444.822170104885 5782.758424634605 4275.241139336881 3927.3327735286325 4399.913108648012 4700.12494383653 0.3443811958555072 1.0810013935754774 1.2434361227211488 0.9072948425604495 0.7329214034240141 1.2303414257567296 0.9096015936646925 0.8355805048711966 0.9361268394402582 1.0 12.19848339325182 -4.75612771016628 24.99159039807526 0.9840027737260797 0.34438018915496266 0.6106083533331845 0.15376472583290374 119.6570648768078 562929.5830049287 0.03981190972635476 0.33116860312451435 1.7533648253833208e-05 4.75612771016628 -0.639622584571117 FPVPHNGSSEATLPAQMSTLHVS(ph)PPPSADPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FPVPHNGSSEATLPAQMSTLHVSPPPSADPAR 32 0 P50479;P50479-2;C9J542 P50479 PDLIM4 PDZ and LIM domain protein 4 1 FPVPHNGSSEATLPAQMS(0.024)T(0.024)LHVS(0.889)PPPS(0.062)ADPAR 79.373 1.5255999999999998e-07 9507300.0 2337.6 7466.5 19122.0 13638.0 19381.0 17178.0 12367.0 13046.0 12497.0 10525.0 True False 2733.3095102954712 8207.724775620549 19577.94100058883 12873.90707499257 15583.432177672606 16277.155439859287 11195.508230673613 12703.556323379586 12679.74498299878 12433.09918414584 0.21984136616402702 0.6601511541134242 1.5746629790868065 1.03545438545273 1.2533827605544994 1.3091792479718352 0.9004599790331963 1.021752994585503 1.0198378373082917 1.0 13.601898339679918 -5.011185414311911 4.903003676249184 1.1391827736725573 0.29521196612033146 0.709558354115517 0.1887170664574635 0.08621447289699696 6.037475805514919 0.048522063287986195 0.17016909914225725 9.745734720600981e-06 5.011185414311911 -0.8439708075522259 down FPY(ph)LDPPNER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FPYLDPPNER 10 0 Q8IX18-4;Q8IX18-3;Q8IX18-2;Q8IX18 Q8IX18-4 DHX40 Probable ATP-dependent RNA helicase DHX40 1 FPY(1)LDPPNER 93.429 0.0098589 7296400.0 18109.0 20794.0 19311.0 16947.0 13478.0 14918.0 20084.0 14247.0 20550.0 14943.0 True False 21174.496030946553 22858.290897241517 19771.44747737534 15997.514532915315 10837.082652632549 14135.673818361909 18181.498124431873 13873.031345944288 20850.50487321955 17652.04761127709 1.1995489983507144 1.294937074758307 1.120065383505099 0.9062696229470417 0.613927794173251 0.8007951332133997 1.029993716582576 0.7859162660019929 1.181194688139132 1.0 14.107547923232541 -5.643398493625368 3.254169410970577 0.8816562885935516 1.2415171369586548 0.4768008424090717 0.14785805702404667 0.19876106964924567 4.132273382213947 0.042531852027727635 0.08000234505170777 2.2730108373421652e-06 5.643398493625368 0.35986084836510324 FQAPS(ph)PSTLLR ddPTM_PC-9_AZD4547_30min_R2 1 FQAPSPSTLLR 11 0 Q6P9B9 Q6P9B9 INTS5 Integrator complex subunit 5 1 FQAPS(0.98)PS(0.016)T(0.004)LLR 105.66 0.0025308 3962300.0 18865.0 17703.0 22700.0 43393.0 23928.0 27236.0 24859.0 25300.0 20756.0 20763.0 True False 24863.67758362365 23425.148548966685 22398.98316808348 33389.414265166946 20606.010227344796 25532.928614452027 27071.40284173589 21390.466336162994 21853.119785786177 20036.093689765345 1.2409443661328199 1.1691474851174462 1.1179316445063903 1.6664632728395867 1.0284444935426995 1.2743466371139263 1.3511317755298906 1.067596641709131 1.09068764221985 1.0 14.29031364238706 -7.781527833984356 22.806551714062227 1.0593560166524196 1.2615985122128908 0.2641946860286828 0.16144400644768034 131.23042497528473 148980.91495354852 0.08673200749626085 0.04178887255400888 1.653758791779603e-08 7.781527833984356 0.20224249556047114 FQAPS(ph)PSTLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FQAPSPSTLLR 11 0 Q6P9B9 Q6P9B9 INTS5 Integrator complex subunit 5 1 FQAPS(0.964)PS(0.018)T(0.018)LLR;FQAPS(0.872)PS(0.096)T(0.032)LLR 71.268 0.030151999999999998 3523270.0 21467.6 17921.8 16306.9 24596.8 25049.0 22081.7 27702.0 23171.6 22295.7 20314.8 True False 25101.64067557282 19700.957862950032 16695.718340262625 23218.721039901546 20140.828265751046 20923.6967793888 25077.86601488807 22563.3700523396 22621.73243317964 23997.712428131694 1.0460013949557554 0.8209514936871765 0.6957212438586775 0.967538931447609 0.8392811742397849 0.871903805083549 1.045010689664326 0.940230037338448 0.9426620350138442 1.0 14.5506092676381 -7.172931038853428 8.373908935960289 0.9768389685782283 0.8654334529742324 0.2521617466185221 0.09067084536790768 0.478806497507139 41.386474763132775 0.03502590028991351 0.027111364099179688 6.715354768454937e-08 7.172931038853428 -0.11140551560399592 FQDGDLTLYQSNTILR ddPTM_PC-9_AZD4547_30min_R2 2 FQDGDLTLYQSNTILR 16 0 P09211;A8MX94;A0A087X2E9 P09211 GSTP1 Glutathione S-transferase P 0 ; 266.07 2.4809e-68 21375000.0 35127.0 34300.0 51222.0 59982.0 49937.0 52017.0 43975.0 54407.0 40996.0 43941.0 False True 46296.65531301079 45386.80422694216 50542.76281213973 46154.07661266206 43004.10952536429 48764.368766997766 47888.68980913696 45999.64829848297 43162.96486500722 42402.63896459949 1.0918342924755764 1.0703768759494907 1.1919721047158442 1.0884717965595139 1.0141847435785056 1.1500314593086873 1.1293799390438313 1.0848298460123318 1.017931098605502 1.0 15.371866434495129 -8.251368772816768 3.031422039283229 1.0018372708206271 1.1049106497601053 0.41841590414333396 0.044884565792241926 0.2600032963193368 4.522011580182094 0.041736014255400196 0.01212958358897566 5.6057177512806e-09 8.251368772816768 0.10307337893947821 FQDGDLTLYQSNTILR ddPTM_PC-9_Lapatinib_30min_R1 2 FQDGDLTLYQSNTILR 16 0 P09211;A8MX94;A0A087X2E9 P09211 GSTP1 Glutathione S-transferase P 0 ; 184.0 3.641e-07 63060000.0 86884.0 79840.0 94505.0 81852.0 81564.0 104141.0 84585.0 80626.0 101814.0 74956.0 False True 85645.01822742577 79655.13538535502 86735.16369984968 87871.66913026778 76766.56588099386 99687.13219452814 88964.39742241648 84372.17829968376 90346.63517104954 87912.04472740802 0.9742125608952482 0.9060776100970522 0.9866129717354711 0.9995407273569232 0.8732201158444973 1.1339416857340943 1.0119705177859477 0.9597339996049409 1.0276934799001722 1.0 16.423773220436374 -6.744219393283414 24.999678773496193 1.0232327770221508 0.9506235494782365 0.34536919372909136 0.05403267288961891 315.05511725087814 457390.9326331683 0.01796943034305165 0.017927333676456665 1.8021071373402024e-07 6.744219393283414 -0.0726092275439143 FQELLAS(ph)PAYR ddPTM_PC-9_AZD4547_30min_R2 2 FQELLASPAYR 11 0 Q9NSI2-2;Q9NSI2 Q9NSI2-2 FAM207A Protein FAM207A 1 FQELLAS(1)PAYR;FQELLAS(0.974)PAY(0.026)R 98.58200000000001 0.0049165 6033700.0 29893.0 27161.0 37570.0 50702.0 38264.0 37584.0 31356.0 47920.0 32290.0 40837.0 True False 39398.35218697387 35940.2620876961 37071.79725219807 39013.43723809129 32951.70408471756 35233.86653860938 34146.62325537915 40515.06509205256 33996.78347865849 39407.309059815416 0.9997727103662939 0.912020205011797 0.9407340449439893 0.9900051073995872 0.8361825476258974 0.8940947093121413 0.8665048202999297 1.0281104205962328 0.862702485649441 1.0 15.26617561751529 -11.343671119120257 2.627358636248259 1.0252670728468127 0.9252362649468755 0.11870547873228854 0.06083489113088447 36919373.60606456 22877814.392995104 5883830.321362725 0.01458790771754301 4.532406783606848e-12 11.343671119120257 -0.10003080789993724 FQELLAS(ph)PAYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FQELLASPAYR 11 0 Q9NSI2-2;Q9NSI2 Q9NSI2-2 FAM207A Protein FAM207A 1 FQELLAS(1)PAYR;FQELLAS(1)PAYR 83.87700000000001 0.034931 3221500.0 24523.0 24689.0 27018.0 29539.0 32702.0 25070.0 25882.0 20849.7 18500.4 17334.7 True False 28674.259548672086 27139.96075608329 27662.2115863356 27884.025596730116 26294.27785327123 23755.28506678729 23430.269590546995 20302.417467083196 18770.9333506818 20477.343888590298 1.4002919375031349 1.3253652868136532 1.3508691233021004 1.3617012903839898 1.284066820205234 1.1600764823812633 1.1442045275999895 0.9914575629310709 0.9166683654290102 1.0 14.32174097539179 -7.19517818624683 0.9305280831953671 0.9475689301615879 1.3647716291049679 0.9488659316591707 0.037828842912644565 0.11567535536363852 0.1979363995675947 0.028005279389534007 0.017059595996976103 6.380016674201434e-08 7.19517818624683 0.4172026989433799 FQELLAS(ph)PAYR ddPTM_PC-9_Lapatinib_30min_R1 2 FQELLASPAYR 11 0 Q9NSI2-2;Q9NSI2 Q9NSI2-2 FAM207A Protein FAM207A 1 FQELLAS(1)PAYR;FQELLAS(1)PAYR 113.54 0.0015507 5527600.0 54417.0 51606.0 56688.0 47376.0 46755.0 45375.0 39888.0 34536.0 53995.0 26666.0 True False 53641.00360114437 51486.5094776632 52027.33146200805 50860.18908170303 44004.962823866714 43434.41702429121 41953.20546651707 36140.66863986658 47913.514507443186 31275.182569788478 1.7151299910543467 1.6462416922035388 1.6635340607816609 1.6262155774218718 1.407024970219521 1.3887822054234285 1.3414216007500932 1.1555701892137988 1.5319979156165557 1.0 14.932730685739415 -1.5228787452803376 0.08790794586642801 0.679350212798226 3.6775874137570637 0.7655322362952064 0.1081328539666296 73.7062057812982 0.4690915176037583 2.1573489242847064 26.670386022656384 0.029999999999999995 1.5228787452803376 2.9982372009588376 FQEQECPPS(ph)PEPTRK ddPTM_PC-9_AZD4547_30min_R2 2 FQEQECPPSPEPTRK 15 1 P62070-2;P62070-3;P62070;P62070-4 P62070-2 RRAS2 Ras-related protein R-Ras2 1 FQEQECPPS(0.984)PEPT(0.016)RK;FQEQECPPS(0.906)PEPT(0.094)RK 137.85 6.7068e-05 5635600.0 22617.0 27613.0 31971.0 33095.0 32141.0 24528.0 26670.0 31941.0 23430.0 24573.0 True False 29808.73553717552 36538.362248354366 31547.043650519707 25465.45906265298 27678.776944044177 22994.260282540727 29043.578333364017 27005.252381161343 24668.461966706967 23712.706749439076 1.2570785719298216 1.5408769076612767 1.3303856022790799 1.0739161636726842 1.1672550601883067 0.9697020473246757 1.2248107582256944 1.1388515308063747 1.040305614511532 1.0 14.533372731998647 -5.670599833871273 4.316396651099336 1.0974945675057182 1.4064775695711786 0.6517928617370238 0.09691213501860997 0.12123911192329138 4.083382000142238 0.025511147204997107 0.045309859177198625 2.1350112418233803e-06 5.670599833871273 0.3089830020654605 FQETEFLS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 2 FQETEFLSPPR 11 0 P42166 P42166 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin 1 FQETEFLS(1)PPR;FQETEFLS(1)PPR 129.54 0.0002545 42061000.0 29199.7 23641.8 32555.0 40781.8 35517.7 30836.8 24432.1 38922.3 30738.8 33257.1 True False 38484.59720850974 31283.54950940296 32123.299428940893 31380.186082529097 30586.680435128917 28908.570021226842 26606.509568750775 32907.75288047577 32363.590213496045 32092.77905167339 1.1991668638775321 0.9747846847115524 1.000951004499123 0.9777958472216778 0.9530704831102514 0.9007811375474971 0.8290497225531938 1.025394305288743 1.008438383020262 1.0 14.969961103742877 -2.1637966725373956 1.2331112872447356 0.9524001990257183 199.95690227830517 0.6057740794533575 0.05653630102161497 872.7918653287343 2.1674666746591664 0.017725972915779067 490327.4131182722 0.0068580923263551405 2.1637966725373956 199.00450207927943 FQETEFLS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FQETEFLSPPR 11 0 P42166 P42166 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin 1 FQETEFLS(1)PPR;FQET(0.003)EFLS(0.997)PPR 138.2 9.900200000000001e-05 15834400.0 33370.0 33291.0 33006.0 33071.0 34952.0 32640.0 31744.0 30488.0 26268.0 21513.0 True False 39018.88191245719 36595.91046744577 33792.988215952064 31218.13908762862 28103.406505031384 30928.300940563942 28736.97851334222 29687.72230470619 26652.119805826347 25413.1366031857 1.535382370217375 1.4400391041402674 1.3297448773684983 1.2284252658412589 1.1058613875120178 1.2170202137380743 1.1307922733843037 1.1682037824872291 1.0487536513885236 1.0 14.63328682981643 -1.5228787452806352 0.28111247214957413 1.042979446691747 5.030572452554629 0.920811284881331 0.04549709460544472 13.717324926387384 0.19351747840883915 0.05208754587221486 26.902596295111124 0.029999999999979442 1.5228787452806352 3.9875930058628817 FQETEFLS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 3 FQETEFLSPPR 11 0 P42166 P42166 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin 1 FQET(0.01)EFLS(0.99)PPR;FQET(0.057)EFLS(0.943)PPR;FQETEFLS(1)PPR 148.89 0.00029502 40984200.0 35149.9 32337.3 36307.0 31940.6 36891.3 28633.0 26524.2 21352.3 35256.4 26159.2 True False 34648.65598029781 32262.42496864777 33321.97860907292 34289.618274718094 34721.426265086426 27408.433336783022 27897.493292092655 22344.405808403488 31285.45296564904 30680.782865057008 1.1293276358915827 1.0515515562476774 1.0860863217093466 1.1176252713476638 1.1316994881715157 0.8933420459749437 0.9092823157347037 0.7282866902934215 1.019708431276071 1.0 14.90504767533442 -6.7668078759242745 24.974434807239774 0.8930891746342765 1.1002296736176078 0.6062494073440234 0.07719699003384799 82.09115904365596 381888.4215647777 0.02581834219581863 0.02342377153439293 1.7107719624927149e-07 6.7668078759242745 0.2071404989833313 FQFDGDKK ddPTM_PC-9_Lapatinib_30min_R1 1 FQFDGDKK 8 1 P52209-2;P52209;K7ELN9 P52209-2 PGD 6-phosphogluconate dehydrogenase, decarboxylating 0 66.962 0.030133999999999998 16356000.0 118320.0 108490.0 132690.0 124580.0 116500.0 86100.0 102380.0 113570.0 91508.0 95902.0 False True 116632.73510276967 108238.79807060573 121780.74039821229 133742.0287866974 109647.69904781262 82417.70370890299 107680.73545081267 118846.87680766871 81201.40541804064 112478.53291861733 1.0369332891917968 0.9623062753576345 1.082702069792513 1.1890449254300377 0.974832229783323 0.7327416314056608 0.9573447719906157 1.0566183050561224 0.7219280276067707 1.0 16.77929015670493 -6.520771512382578 24.99780180901407 0.8959686149330395 1.0638653330295091 0.35081670046202784 0.11153268088101542 98.23393335066193 1165353.6351497064 0.03664426676999847 0.037222533339218995 3.0145916204234856e-07 6.520771512382578 0.16789671809646967 FQHFNT(ph)VLEAY(ph)IQQHFSAT(ph)LAYK ddPTM_PC-9_AZD4547_30min_R2 1 FQHFNTVLEAYIQQHFSATLAYK 23 0 E5RFJ0;Q92608 E5RFJ0 DOCK2 Dedicator of cytokinesis protein 2 3 FQHFNT(0.957)VLEAY(0.842)IQQHFS(0.199)AT(0.533)LAY(0.469)K 49.768 0.036324 0.0 4755.5 7415.5 8168.7 8182.8 9553.9 9334.7 8394.5 9206.0 9224.0 9237.7 True False 6267.650079455201 9812.415356993872 8060.377700666238 6296.381882999745 8227.505897318186 8750.999733342825 9141.594237698693 7783.42423283464 9711.561808830775 8914.290934737048 0.7031013599782273 1.1007510781095364 0.9042085074042966 0.7063244770780498 0.9229568518183975 0.9816820874941481 1.0254987530276687 0.8731400276049252 1.0894373854219785 1.0 13.121904331461089 -6.599935027712483 4.642470840552926 0.9869236943617962 0.8684224080073232 0.23952748985983985 0.11592825493669516 0.370141483291422 14.875558161228842 0.03901029813449076 0.03918171158241327 2.512262248432835e-07 6.599935027712483 -0.11850128635447299 FQNYS(ph)PPPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FQNYSPPPTK 10 0 Q8TEC5-3;Q8TEC5-2;Q8TEC5 Q8TEC5-3 SH3RF2 Putative E3 ubiquitin-protein ligase SH3RF2 1 FQNY(0.003)S(0.889)PPPT(0.108)K 68.515 0.040787000000000004 8093100.0 58591.0 52605.0 52217.0 67392.0 80008.0 64768.0 68682.0 63322.0 60807.0 44075.0 True False 68509.29907500082 57827.27674566655 53462.051314075274 63616.24472781184 64331.00674223368 61371.45206245235 62175.94374538087 61659.86459520489 61696.18733945803 52065.448602492 1.3158303810662215 1.1106651012875126 1.0268239830649692 1.2218514664784237 1.235579611219457 1.1787366422406076 1.1941881884103263 1.1842760650343014 1.1849737012830632 1.0 15.668038675933705 -10.500784888152756 5.290619979597996 0.9999992970082734 1.1797322493529674 0.36832405958427816 0.07198954859043187 6.128513510894805e-07 1.1847493869107808e-07 0.07153752630476971 0.017350330660887626 3.156567726310504e-11 10.500784888152756 0.179732952344694 FQNYS(ph)PPPTK ddPTM_PC-9_Lapatinib_30min_R1 2 FQNYSPPPTK 10 0 Q8TEC5-3;Q8TEC5-2;Q8TEC5 Q8TEC5-3 SH3RF2 Putative E3 ubiquitin-protein ligase SH3RF2 1 FQNYS(1)PPPTK;FQNY(0.3)S(0.7)PPPTK 101.53 0.0035655 21161700.0 132578.0 104972.0 121319.0 99633.0 104888.0 102693.0 99613.0 102753.0 112989.0 91174.0 True False 130687.41340817242 104728.94378346048 111344.62012488296 106960.34318594464 98718.69405774219 98301.05977907515 104770.47372984773 107527.27949826853 100262.98899308254 106933.30441828158 1.2221394832892658 0.9793856493370999 1.0412529635233756 1.000252856374449 0.9231800569034412 0.9192744983785366 0.9797740217587058 1.0055546313023636 0.9376217216751541 1.0 16.70635172539994 -2.168041686467659 1.2328016705452693 0.968788094036075 199.99985463469065 0.7791383275789098 0.038814922040843275 533.6498048708237 1.368031311913776 0.011634770812023654 299723.3239098122 0.006791384412720848 2.168041686467659 199.03106654065456 FQPGETLTEILETPATSEQEAEHQR ddPTM_PC-9_Lapatinib_30min_R1 1 FQPGETLTEILETPATSEQEAEHQR 25 0 P46940;H0YLE8 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 0 153.57 1.528e-07 2029700.0 3230.6 4145.2 5215.9 3869.3 4474.8 5118.6 4821.7 3404.5 3437.6 3384.6 False True 3184.5310515805163 4135.602044080329 4787.068835956248 4153.8612296064175 4211.601061795291 4899.68941003938 5071.344033240707 3562.685498738295 3050.421288467203 3969.6236003039867 0.8022249392452853 1.0418121364866009 1.2059251248883303 1.0464118636558697 1.0609572810562629 1.2342957175244955 1.277537757698829 0.8974869804949444 0.768440939396271 1.0 11.95478650217665 -7.909864825473826 9.304842620031637 0.8672986513947616 1.099674642240096 0.3261362487229502 0.1358718263950329 0.3227093599684473 29.929213859622365 0.07699253365603587 0.03691098980156089 1.2306517526103108e-08 7.909864825473826 0.23237599084533445 FQPPQVPDQAPAEAPTEKTEVS(ph)PVPR ddPTM_PC-9_AZD4547_30min_R2 2 FQPPQVPDQAPAEAPTEKTEVSPVPR 26 1 E9PPY3;O43159 E9PPY3 RRP8 Ribosomal RNA-processing protein 8 1 FQPPQVPDQAPAEAPT(0.103)EKT(0.071)EVS(0.826)PVPR;FQPPQVPDQAPAEAPT(0.037)EKT(0.036)EVS(0.927)PVPR 94.34899999999999 2.3475e-09 20829600.0 53488.0 28133.8 57741.0 143844.0 103063.0 60183.0 45847.0 53636.0 46164.0 75238.0 True False 70496.07138048566 37227.500663555285 56975.31661270084 110682.98816764617 88754.4814468754 56419.74749609218 49927.29418259245 45347.78863266552 48604.13479432611 72603.94052066501 0.9709675656023189 0.5127476607548505 0.7847413818604535 1.5244763214490107 1.2224471676108752 0.7770893300210562 0.6876664520485883 0.6245912867464588 0.669442105287551 1.0 16.14776023101215 -6.975903549616109 23.00629442600454 0.7167461291618873 0.9933824086352081 0.18094060307839177 0.2648364100333053 171.88883616608373 164110.46084919162 0.10413923263550524 0.09183468240718616 1.0570522388226586e-07 6.975903549616109 0.2766362794733208 FQPPQVPDQAPAEAPTEKTEVS(ph)PVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FQPPQVPDQAPAEAPTEKTEVSPVPR 26 1 E9PPY3;O43159 E9PPY3 RRP8 Ribosomal RNA-processing protein 8 1 FQPPQVPDQAPAEAPT(0.182)EKT(0.182)EVS(0.637)PVPR;FQPPQVPDQAPAEAPT(0.034)EKT(0.018)EVS(0.947)PVPR;FQPPQVPDQAPAEAPT(0.003)EKT(0.028)EVS(0.969)PVPR 104.09 5.1598e-10 13982200.0 48346.4 15678.2 27079.7 51813.8 52253.5 75557.0 54192.8 80340.4 66203.6 41682.0 True False 56530.49063507399 17234.628082385872 27725.382748334163 48910.8407686061 42014.801779888345 71594.65790950334 49059.26566210473 78231.54962769017 67171.70240509395 49238.616645469556 1.1480925843653929 0.35002258910886014 0.5630820814476553 0.9933431136129691 0.8532896462629221 1.454034714764692 0.9963575137649338 1.5888250921218408 1.364207749554524 1.0 15.587502609553056 -6.4350901403964045 1.4632167377862075 1.3069466504729053 0.6773565278144184 0.44263108518819616 0.27254486403545936 0.33619358723461085 1.4602917408030047 0.10549121029740242 0.12570699119572568 3.672060767881319e-07 6.4350901403964045 -0.6295901226584869 FQPPQVPDQAPAEAPTEKTEVS(ph)PVPR ddPTM_PC-9_Lapatinib_30min_R1 2 FQPPQVPDQAPAEAPTEKTEVSPVPR 26 1 E9PPY3;O43159 E9PPY3 RRP8 Ribosomal RNA-processing protein 8 1 FQPPQVPDQAPAEAPT(0.095)EKT(0.104)EVS(0.801)PVPR;FQPPQVPDQAPAEAPT(0.101)EKT(0.101)EVS(0.798)PVPR 102.06 8.6229e-10 15166800.0 93733.0 40017.0 53886.0 42805.0 39703.0 37975.0 26434.0 25163.1 49170.0 30599.0 True False 92396.35023147291 39924.343095137134 49455.70108597529 45953.02249329403 37367.747599101276 36350.89777404866 27802.623177444642 26332.269488412876 43631.956816945676 35887.996379395394 2.57457533306376 1.1124706621420402 1.3780569013423556 1.280456618627986 1.0412324835318882 1.01289850204396 0.7747053606315882 0.7337347343116427 1.2157813536226383 1.0 15.131213759538218 -2.6542714206093154 1.1311743704212769 1.0060033535888937 199.9999991872851 0.8303976698935893 0.20311527404178617 83.18073117614426 1.0804246473512182 0.0647790011072768 41914.28884313542 0.0022168105488017203 2.6542714206093154 198.99399583369623 up FQPSSVLS(ph)PYER ddPTM_PC-9_AZD4547_30min_R2 2 FQPSSVLSPYER 12 0 Q7Z6J9;J3QLM6 Q7Z6J9 TSEN54 tRNA-splicing endonuclease subunit Sen54 1 FQPS(0.003)S(0.036)VLS(0.959)PY(0.002)ER;FQPS(0.002)S(0.002)VLS(0.996)PYER 88.09200000000001 0.0082229 4127000.0 19549.4 15589.800000000001 26180.0 30314.0 23935.6 23571.0 24296.1 29917.0 21521.3 21353.4 True False 25765.702547219316 20628.897974845 25832.836094291873 23325.57564663128 20612.55509853036 22097.101643826147 26458.405832217675 25294.015074268285 22658.871981395256 20605.82396546911 1.250408748050893 1.0011197809616619 1.253666737014841 1.131989465003675 1.0003266616793645 1.0723716596267199 1.2840256170564315 1.2275177695711448 1.0996343567414053 1.0 14.33076453339494 FQPSSVLS(ph)PYER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FQPSSVLSPYER 12 0 Q7Z6J9;J3QLM6 Q7Z6J9 TSEN54 tRNA-splicing endonuclease subunit Sen54 1 FQPSS(0.004)VLS(0.994)PY(0.002)ER 112.02 0.0010032 2357700.0 18995.0 24787.0 23780.0 23093.0 26244.0 19787.0 22678.0 19642.0 19439.0 17621.0 True False 22210.4783316489 27247.689548423845 24347.00538615221 21799.174078516156 21101.67659413032 18749.33488697727 20529.7756654982 19126.418312419275 19723.258600025063 20815.54781224074 1.0670138750125933 1.3090066038233514 1.1696547986997858 1.0472544021011538 1.0137459164885068 0.9007370382993996 0.9862712166251763 0.9188525079878916 0.9475253199162336 1.0 14.345373906588872 -5.978824880223726 1.8414921444367238 0.951714678529415 1.1998878174486005 0.7099155963707473 0.06317795578063216 0.16823789978031065 1.1508741838653085 0.019753551713230476 0.03273664848923079 1.0499657190778908e-06 5.978824880223726 0.24817313891918547 FQS(ph)LGVAFYR ddPTM_PC-9_AZD4547_30min_R2 1 FQSLGVAFYR 10 0 C9IZZ0;C9J592;C9J8S3;P51149 C9IZZ0 RAB7A Ras-related protein Rab-7a 1 FQS(1)LGVAFYR 98.156 0.004868 2941900.0 18597.0 15650.0 25208.0 29786.0 28155.0 18854.0 22729.0 27756.0 22453.0 22177.0 True False 24510.459158369962 20708.55644756983 24873.725449385394 22919.297889112593 24246.16424067591 17675.056399503534 24751.83696809264 23466.947969428456 23639.81974129201 21400.58998015344 1.145316983368242 0.9676628759662519 1.1622915757207106 1.0709657028319115 1.1329670940456038 0.8259144451575912 1.1565960093178316 1.0965561225737852 1.1046340200534281 1.0 14.385362949526755 -3.5509351584724165 10.775393154477465 1.0667130086866417 1.0715640444524108 0.0 0.10118033772224931 0.0 0.0 0.022205605224839893 0.0 0.0002812320687349924 3.5509351584724165 0.004851035765769174 FQS(ph)VESGANNVVFIR ddPTM_PC-9_AZD4547_30min_R2 1 FQSVESGANNVVFIR 15 0 H3BNW0;Q9NXG2 H3BNW0 THUMPD1 THUMP domain-containing protein 1 1 FQS(1)VESGANNVVFIR 106.87 0.00089833 2925500.0 5190.2 5010.2 6574.7 12297.0 10288.0 7963.2 6993.8 9007.1 5547.5 7275.6 True False 6840.575637133506 6629.649170198998 6487.515182167331 9462.116636756113 8859.688783806556 7465.2598451536305 7616.234651214144 7615.259657567338 5840.729524554285 7020.88345852029 0.974318357162307 0.9442756327415598 0.9240311736401658 1.347710255078117 1.2619051200821112 1.0632935141650957 1.0847971905830964 1.0846583200759063 0.8319080581612825 1.0 12.777436865196451 -11.27164931112955 2.6393443609902905 0.9855538504733901 1.0665107093371182 0.010172390818758537 0.1472093425944414 108840902.97297758 84879640.88175051 10264648.713491453 0.03928215772423676 5.3499618961363155e-12 11.27164931112955 0.08095685886372816 FQSDSSSYPTVDSNS(ph)LLGQSR ddPTM_PC-9_AZD4547_30min_R2 2 FQSDSSSYPTVDSNSLLGQSR 21 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 FQSDSSSYPT(0.001)VDS(0.02)NS(0.979)LLGQSR;FQSDSSSYPTVDS(0.001)NS(0.998)LLGQSR 217.18 4.8563999999999994e-32 22376000.0 40755.0 47532.0 54075.0 73527.0 42923.0 47423.0 50171.0 55820.0 44723.0 41461.0 True False 53714.2422433386 62895.789461079126 53357.93016802267 56576.48613082596 36963.882354911446 44457.632313230984 54636.12180589447 47194.30161599282 47086.966476185924 40009.46300974625 1.3425384447237867 1.5720228348417922 1.3336327497078566 1.4140776175137368 0.9238784920934103 1.1111779306410878 1.3655799827302153 1.1795784813331875 1.176895737508789 1.0 15.288053645114369 -6.157449438339487 10.310730529980642 1.1464720654708678 1.421819277674158 0.5552305762989882 0.12606493591242293 0.3872056316264227 36.13934579034954 0.03832282762756088 0.049508864657482776 6.959059691151879e-07 6.157449438339487 0.2753472122032903 FQSDSSSYPTVDSNS(ph)LLGQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FQSDSSSYPTVDSNSLLGQSR 21 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 FQSDSSSYPTVDSNS(1)LLGQSR 292.49 1.0500999999999996e-234 0.0 15286.0 17912.0 19453.0 25123.0 13860.0 13861.0 19968.0 15306.0 13954.0 11903.0 True False 17873.617887738103 19690.184983715986 19916.833295913333 23715.439759864952 11144.232494842492 13134.104759104066 18076.486484199148 14904.233718047533 14158.050851625581 14060.919675903853 1.271155678271035 1.4003483013603288 1.4164673261056129 1.6866208119022268 0.7925678228530331 0.9340857541211856 1.2855835109546039 1.0599757385421142 1.0069078821272397 1.0 13.779403338716206 -6.262679323939968 24.999646067425015 1.0258503589812038 1.4386137103391192 0.6644953476709426 0.14966593771729686 75.4011619201123 1520227.444734711 0.04803052509510254 0.05754322325697578 5.461609887308308e-07 6.262679323939968 0.4127633513579154 FQSDSSSYPTVDSNS(ph)LLGQSR ddPTM_PC-9_Lapatinib_30min_R1 2 FQSDSSSYPTVDSNSLLGQSR 21 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 FQSDSSSYPT(0.005)VDS(0.086)NS(0.907)LLGQS(0.002)R;FQSDSSSYPT(0.002)VDS(0.429)NS(0.569)LLGQSR 258.03 2.9049999999999996e-73 17854000.0 56629.0 48759.0 68736.0 44857.0 39203.0 36952.0 38905.0 39089.0 42144.0 21905.7 True False 55821.46007551325 48646.10153124404 63084.79140863297 48155.93341856538 36897.156616063476 35371.649099319206 40919.31053637302 40905.217641410265 37397.29892400564 25692.07105748951 2.1727115712316505 1.8934285765593504 2.4554186880252726 1.8743500012439602 1.4361301015204675 1.376753513571184 1.5926824445102339 1.5921339136062356 1.4555968975924163 1.0 14.649035571226001 -6.10426256393719 3.5887734989805575 1.446808682948181 2.149713898843398 0.7412638464051029 0.2038870260882438 0.1260170621997452 2.979758290846202 0.05971160889782997 0.08079164069996529 7.86570104659394e-07 6.10426256393719 0.7029052158952172 FQSPQIQATIS(ph)PPLQPK ddPTM_PC-9_AZD4547_30min_R2 2 FQSPQIQATISPPLQPK 17 0 A0A087WYN9;Q7Z478 A0A087WYN9 DHX29 ATP-dependent RNA helicase DHX29 1 FQSPQIQAT(0.001)IS(0.999)PPLQPK;FQSPQIQAT(0.011)IS(0.989)PPLQPK 177.41 4.0913999999999995e-06 102411000.0 50062.0 48374.0 64695.0 83976.0 75651.0 66806.0 56916.0 67977.0 58840.0 62665.0 True False 65980.67464571254 64009.94949487178 63837.10202903793 64616.6306162666 65148.164481313215 62628.6102591086 61981.41373909805 57472.71660606126 61950.16227575923 60471.11742374151 1.0911105575139899 1.0585210299047805 1.0556626824291973 1.0685536065668522 1.0773434865573603 1.0356780712393456 1.024975498712441 0.9504159845985738 1.02445869888022 1.0 15.883958617821131 -7.220179000303935 1.978250639482943 0.9913313671497642 1.0682341556971768 0.7156092374558021 0.02099814079038588 0.17071013630977958 1.3063708976923945 0.00995449016969373 0.006531897763615729 6.023112842216765e-08 7.220179000303935 0.07690278854741261 FQSPQIQATIS(ph)PPLQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FQSPQIQATISPPLQPK 17 0 A0A087WYN9;Q7Z478 A0A087WYN9 DHX29 ATP-dependent RNA helicase DHX29 1 FQSPQIQAT(0.005)IS(0.995)PPLQPK;FQSPQIQAT(0.006)IS(0.994)PPLQPK 191.07 8.3775e-09 80296000.0 61013.0 59278.0 57751.0 61651.0 71172.0 67564.0 73449.0 67014.0 61073.0 51190.0 True False 71341.29583832034 65162.72808534591 59128.00286188716 58196.89434523876 57226.357512476956 64020.8249003756 66491.3789952895 65254.9535072022 61966.07708623544 60470.34178018296 1.1797733192521818 1.0775981442641807 0.9778016978442859 0.9624039261559253 0.9463541271273399 1.0587144543204183 1.0995700873825676 1.0791232790516032 1.0247350231868981 1.0 15.883940112717541 -4.869879938940079 3.201971783058429 1.0212699520151383 1.1883340279908554 0.5189092253002408 0.0474846449519738 0.2726991974462723 4.653392206938879 0.014153179600176617 0.10183842514458986 1.349335856020949e-05 4.869879938940079 0.16706407597571715 FQSPQIQATIS(ph)PPLQPK ddPTM_PC-9_Lapatinib_30min_R1 2 FQSPQIQATISPPLQPK 17 0 A0A087WYN9;Q7Z478 A0A087WYN9 DHX29 ATP-dependent RNA helicase DHX29 1 FQSPQIQAT(0.139)IS(0.861)PPLQPK;FQSPQIQAT(0.461)IS(0.539)PPLQPK 138.77 7.2871e-05 71523000.0 127320.0 114580.0 124084.0 110603.0 121440.0 117560.0 103696.0 110146.0 140519.0 92670.0 True False 125504.39345237156 114314.69704977416 113882.29249809138 118737.11358079205 114297.13796022617 112532.23284574482 109064.87149157526 115263.7852677422 124692.27048933068 108687.8860249868 1.1547229230635576 1.0517703603462651 1.0477919542193543 1.0924594996124497 1.051608805179538 1.0353705179239039 1.0034685141129878 1.0605025958573124 1.1472508579352123 1.0 16.72983162597415 -4.760277132070832 24.664787213093813 1.0550584684035116 1.1547230651068197 0.3598814531673985 0.040104863705277806 27.969692896356243 593258.7714558668 0.00998727787522093 0.05962941517504958 1.736692256718972e-05 4.760277132070832 0.09966459670330807 FQSQADQDQQASGLQS(ph)PPSR ddPTM_PC-9_AZD4547_30min_R2 2 FQSQADQDQQASGLQSPPSR 20 0 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 FQSQADQDQQASGLQS(0.999)PPS(0.001)R;FQSQADQDQQASGLQS(0.999)PPS(0.001)R 275.76 1.6527999999999995e-92 14362100.0 25962.4 30355.0 36957.0 38454.0 34466.0 33671.0 36963.0 47349.0 31842.0 32713.0 True False 34217.903148532794 40166.660125621835 36466.92603272518 29589.024408377627 29680.990826465473 31565.547047188058 40252.635393180884 40032.30002177792 33525.10311326863 31567.72782706226 1.0839520454556948 1.2723963012373642 1.1551964155450858 0.9373187886842987 0.9402320936453548 0.9999309174266153 1.2751198190030408 1.268140052432256 1.0620055804120423 1.0 14.946162802043874 -10.48733601059549 15.512594495679323 0.9999970922166979 1.1126826596911552 0.06614464755956995 0.12428473492376828 0.0 0.0 0.13432298365127074 0.03257810879660609 3.255847009290402e-11 10.48733601059549 0.11268556747445735 FQSQADQDQQASGLQS(ph)PPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FQSQADQDQQASGLQSPPSR 20 0 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 FQSQADQDQQASGLQS(1)PPSR;FQSQADQDQQASGLQS(1)PPSR;FQSQADQDQQASGLQS(0.999)PPS(0.001)R 244.33 4.6758999999999996e-120 4979600.0 21885.9 33782.6 36457.8 29023.7 38469.0 23921.300000000003 28111.1 19472.6 23109.800000000003 19162.8 True False 25590.75060377126 37136.31326657456 37327.09221897646 27397.596185104994 30931.275602027115 22666.82491695808 25448.213101260528 18961.464882925142 23447.73710555376 22636.863947358663 1.1304901007172092 1.6405237648171551 1.648951564394232 1.2103088240852298 1.3664116935082904 1.0013235477170819 1.1241934024271016 0.8376365616288304 1.0358209140665755 1.0 14.466386484319234 -6.625661643853039 1.2596137090073791 0.9703373877105537 1.4664157350986664 0.582892957502511 0.1673865932964604 0.29919068984822983 0.9971292441700197 0.07652393254202126 0.0782737738943624 2.36776368912893e-07 6.625661643853039 0.49607834738811274 FQSQADQDQQASGLQS(ph)PPSR ddPTM_PC-9_Lapatinib_30min_R1 2 FQSQADQDQQASGLQSPPSR 20 0 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 FQSQADQDQQASGLQS(0.995)PPS(0.005)R;FQSQADQDQQASGLQS(0.999)PPS(0.001)R 233.56 4.0789999999999997e-44 15864900.0 10574.7 26130.0 29597.0 26914.0 36046.0 33916.0 27137.0 32592.0 29121.0 24521.0 True False 10423.902838837525 26069.497590422405 27163.64890772389 28893.345342472032 33925.84514916268 32465.491742057526 28542.021077639238 34106.34330294567 25841.086322275263 28759.4221778213 0.36245174796579305 0.9064680586846661 0.9445130274095689 1.0046566709102387 1.1796427946082177 1.1288645349451518 0.9924406999960619 1.185918934395275 0.898525921783067 1.0 14.81174706959766 -4.661919739858687 1.674968793731622 1.0591507937193598 1.2138434120882878e-17 0.8307802720244749 0.09165109155992515 0.5093391264552304 1.1174659363246147 0.024878905814497157 0.9597459054697988 2.178112262950736e-05 4.661919739858687 -1.0591507937193598 down FRAFQQS(ph)T(ph)AASLTS(ph)PRSGNPGY(ph)IVGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FRAFQQSTAASLTSPRSGNPGYIVGK 26 2 A0A0C4DFN5;Q6NUS6-3;Q6NUS6-2;Q6NUS6 A0A0C4DFN5 TCTN3 Tectonic-3 4 FRAFQQS(0.992)T(0.991)AAS(0.147)LT(0.127)S(0.657)PRS(0.216)GNPGY(0.87)IVGK 40.764 0.045367000000000005 0.0 1790.8 1673.9 4545.8 4472.0 4623.8 4102.5 1067.1 4831.2 2008.6 1757.5 True False 2093.9470700877528 1840.0737295802903 4654.189112042505 4221.448338419619 3717.799582226026 3887.3576779615046 966.0165628650292 4704.386119079525 2037.9719751021314 2076.1208376376553 1.0085863173891079 0.8863037720261241 2.2417717830616946 2.0333346026347177 1.790743349243765 1.8724139787473988 0.46529881370692533 2.2659500515550337 0.9816249315338831 1.0 11.019674700798696 -8.409434283352885 21.072652341303744 0.9896781130645826 1.5697301294655033 0.14034111186062415 0.5739070394116914 12.387208019789123 2251.547832520086 0.5602586152806861 0.1446582166915596 3.8955224957836145e-09 8.409434283352885 0.5800520164009206 FRDGPPLR ddPTM_PC-9_AZD4547_30min_R2 1 FRDGPPLR 8 1 Q15056;Q15056-2 Q15056;Q15056-2 EIF4H Eukaryotic translation initiation factor 4H 0 74.255 0.036352999999999996 7429900.0 20785.0 16084.0 25514.0 37712.0 31456.0 29803.0 20132.0 28268.0 18737.0 22565.0 False True 27394.197645142754 21282.838460237257 25175.667689448535 29018.081044591894 27088.8773700835 27939.41369865303 21923.708999148275 23899.830134017997 19727.39956765637 21775.006218251445 1.258056937875012 0.9773975835836198 1.15617269805171 1.3326325032352655 1.244035344861489 1.2830955554554415 1.0068290580221368 1.097580863788023 0.9059652782611468 1.0 14.410385510361614 -7.27646928685518 24.264982605557588 1.0107255056597302 1.2029277251476214 0.5041904472837629 0.09983883970633921 549.3954746311305 886965.3918849402 0.04457864119337002 0.030202509836393897 5.290914130352094e-08 7.27646928685518 0.19220221948789118 FRDGPPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FRDGPPLR 8 1 Q15056;Q15056-2 Q15056;Q15056-2 EIF4H Eukaryotic translation initiation factor 4H 0 82.45200000000001 0.021321 7341700.0 23276.0 23521.0 24514.0 25811.0 29173.0 23780.0 29340.0 33015.0 31965.0 29676.0 False True 27216.167078044735 25856.009435126383 25098.5067298627 24364.893350391063 23456.760070132757 22532.93493770252 26560.702796795023 32148.391232284015 32432.427653161212 35056.02388491324 0.7763620645454182 0.7375625233486282 0.7159541770127597 0.6950272920391515 0.6691220928859432 0.6427692716001323 0.7576644426074153 0.9170575458821343 0.925159902892435 1.0 15.097374751949891 -7.746413022025497 2.906151963084428 0.9531699894943029 0.7050175916370753 0.889315957254031 0.03835105989659588 0.08758860231550791 1.4983239325481583 0.025277996302057813 0.01174994031370597 1.793027613557469e-08 7.746413022025497 -0.24815239785722754 FRDGPPLR ddPTM_PC-9_Lapatinib_30min_R1 1 FRDGPPLR 8 1 Q15056;Q15056-2 Q15056;Q15056-2 EIF4H Eukaryotic translation initiation factor 4H 0 90.37 0.012348 8224900.0 50425.0 31142.0 31424.0 25483.0 30893.0 31860.0 26066.0 21092.0 35977.0 21128.0 False True 49705.930253187515 31069.892612358795 28840.44002014784 27357.10482879598 29075.934477974864 30497.42206928745 27415.569938082477 22072.011320131624 31924.89140539464 24779.946648709636 2.005893352307756 1.253832102740895 1.1638620707704246 1.1040017646777518 1.173365499537463 1.2307299326197516 1.1063611365567685 0.8907206957719974 1.2883357602812702 1.0 14.596885460905087 -4.712189548050183 2.6713418817677748 1.121498022506702 2.2858453250700803 0.8601108754209559 0.10658181833020411 0.21408006602391005 1.698572174288625 0.027183134631028862 0.6056893704042211 1.9400389617842797e-05 4.712189548050183 1.1643473025633784 up FRDQDLAS(ph)CDR ddPTM_PC-9_Lapatinib_30min_R1 1 FRDQDLASCDR 11 1 Q96HJ9-2;A0A0A6YYJ8;Q9Y383-3;Q9Y383-2;Q9Y383 Q96HJ9-2 LUC7L2 Putative RNA-binding protein Luc7-like 2 1 FRDQDLAS(1)CDR 83.85600000000001 0.0058357 2169700.0 5665.7 9530.2 9740.9 9252.8 11239.0 9932.6 11058.0 8239.9 6916.9 11773.0 True False 5584.906079037867 9508.133407433737 8940.040802961374 9933.281778435954 10577.94411672417 9507.805852021487 11630.52913279046 8622.755835233856 6137.8458838139395 13807.94736346357 0.4044704062108298 0.6885986133313827 0.6474561763334289 0.7193887343979779 0.7660765092944857 0.688574891093484 0.842306885059929 0.6244777451897046 0.4445154462317076 1.0 13.75321124956896 -4.458843500689921 1.8861003237533196 0.7098474352837947 3.22045106357648e-11 0.31255095040885816 0.13706827853977405 3.206759469650631 5.447928732311821 0.03575582687864828 5.398072683313006 3.47661419701339e-05 4.458843500689921 -0.7098474352515902 FRDQDLASCDR ddPTM_PC-9_AZD4547_30min_R2 1 FRDQDLASCDR 11 1 Q96HJ9-2;A0A0A6YYJ8;Q9Y383-3;Q9Y383-2;Q9Y383 Q96HJ9-2 LUC7L2 Putative RNA-binding protein Luc7-like 2 0 107.09 0.0030496 6239400.0 21549.0 22450.0 26096.0 18075.0 22914.0 27789.0 24687.0 26108.0 22142.0 18076.0 False True 28401.13375295554 29706.523466322207 25749.94998917649 13908.088005966227 19732.78662443075 26051.349437032142 26884.095174944046 22073.608502155857 23312.380916211077 17443.164741906203 1.6282099133492356 1.7030466607331862 1.476220076470052 0.7973374219503209 1.1312618390299247 1.4934990193863886 1.5412395383938873 1.2654589249578823 1.3364765661018163 1.0 14.09037419393277 -5.528090735338343 24.999025823811728 1.2461860189071035 1.6466296448165387 0.4243614371586024 0.20869750348225838 141.74591703273322 679874.5500423056 0.06148941861188027 0.10695346882915693 2.964212024346258e-06 5.528090735338343 0.4004436259094353 FRDQDLASCDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FRDQDLASCDR 11 1 Q96HJ9-2;A0A0A6YYJ8;Q9Y383-3;Q9Y383-2;Q9Y383 Q96HJ9-2 LUC7L2 Putative RNA-binding protein Luc7-like 2 0 100.04 0.0055917 2165800.0 12881.0 12028.0 13386.0 13745.0 14577.0 13931.0 12091.0 13112.0 13332.0 11871.0 False True 15061.498888653303 13222.06034971728 13705.1730066877 12974.912211891247 11720.741491870062 13200.433835876098 10945.652948740573 12767.82389331237 13526.955278333975 14023.118329215713 1.0740477642033606 0.9428759024425036 0.9773270598547539 0.9252515672537229 0.8358156307824282 0.941333698110096 0.780543434903237 0.9104839304330716 0.9646182083589758 1.0 13.775519577532656 -3.1457389855389484 0.7573429662516701 0.8991378783384926 2.929465314965866 0.3635113928935655 0.062167264309132546 27.510708200279087 1.6088832864812526 0.022866488734098148 80.62555860002215 0.0007149258731561969 3.1457389855389484 2.030327436627373 FRDQDLASCDR ddPTM_PC-9_Lapatinib_30min_R1 1 FRDQDLASCDR 11 1 Q96HJ9-2;A0A0A6YYJ8;Q9Y383-3;Q9Y383-2;Q9Y383 Q96HJ9-2 LUC7L2 Putative RNA-binding protein Luc7-like 2 0 155.47 1.0249e-11 0.0 24750.0 35064.0 17816.0 21586.0 31475.0 28246.0 27566.0 28689.0 31181.0 18692.0 False True 24397.060461405887 34982.81146232572 16351.23725174879 23173.506448785076 29623.702382230906 27037.984424641974 28993.232598526116 30021.99567434365 27669.06742951358 21922.887294475582 1.112857997840174 1.5957209920584297 0.7458523611472103 1.057046279420715 1.351268287991239 1.233322238145856 1.3225097684022766 1.3694362093404087 1.2621087294685858 1.0 14.420150196602792 -6.262106610614497 24.98914574227196 1.2770601947945346 1.1340004472658323 0.07362179966515636 0.2156892435049143 160.89066358376425 6025661.927973879 0.06605361201133181 0.07946539369149737 5.468816978893645e-07 6.262106610614497 -0.14305974752870232 FRDQDLASCDRDR ddPTM_PC-9_AZD4547_30min_R2 1 FRDQDLASCDRDR 13 2 Q96HJ9-2;A0A0A6YYJ8;Q9Y383-3;Q9Y383-2;Q9Y383 Q96HJ9-2 LUC7L2 Putative RNA-binding protein Luc7-like 2 0 94.82 0.014872999999999999 26918000.0 19567.0 16722.0 24879.0 31088.0 21762.0 22033.0 15990.0 25290.0 15358.0 18212.0 False True 25788.898981116567 22127.059483467263 24549.088204350177 23921.141904812073 18740.721939463285 20655.273026957766 17413.079023265484 21382.01160638584 16169.792526021585 17574.403423301374 1.46741248393808 1.2590503899625782 1.3968660905895263 1.361135358546268 1.0663646149499177 1.175304363365846 0.9908204906789613 1.2166564685795294 0.9200763255828385 1.0 14.101188096280964 -6.259883276048733 23.00781011762155 1.074522386012904 1.3649507184505798 0.718670616375043 0.09464949830691358 24.72120273445342 365511.27548499184 0.026560738506873197 0.03245398683322739 5.496885920663357e-07 6.259883276048733 0.29042833243767574 FRDQDLASCDRDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FRDQDLASCDRDR 13 2 Q96HJ9-2;A0A0A6YYJ8;Q9Y383-3;Q9Y383-2;Q9Y383 Q96HJ9-2 LUC7L2 Putative RNA-binding protein Luc7-like 2 0 94.402 0.0153 4076100.0 13282.0 12596.0 18917.0 14557.0 19094.0 17450.0 15104.0 18837.0 13620.0 9056.8 False True 15530.38026854229 13846.447635936045 19368.053023121996 13741.41848443076 15352.667767425875 16534.891281030646 13673.239776509603 18342.54870945127 13819.166733491507 10698.726146410645 1.4516102249941816 1.294214605220215 1.810313934394877 1.2843976279401188 1.4349996025065654 1.545500936723948 1.2780250274091638 1.7144609982941827 1.2916646845968434 1.0 13.385151410600129 -8.532052219112055 22.841484881130402 0.9999999857202985 1.4716920857325273 0.43291555241450663 0.16878485321053197 337.57166395345337 840538.2715116183 0.15234427520841026 0.039335122717905915 2.937296453289431e-09 8.532052219112055 0.47169210001222883 FRDQDLASCDRDR ddPTM_PC-9_Lapatinib_30min_R1 1 FRDQDLASCDRDR 13 2 Q96HJ9-2;A0A0A6YYJ8;Q9Y383-3;Q9Y383-2;Q9Y383 Q96HJ9-2 LUC7L2 Putative RNA-binding protein Luc7-like 2 0 87.641 0.028349 21608000.0 25321.0 18095.0 22435.0 21742.0 22501.0 17974.0 13083.0 14541.0 17376.0 19796.0 False True 24959.91789669729 18053.10213925349 20590.480901604406 23340.97920918582 21177.53541866806 17205.29391944045 13760.373724389357 15216.627944530332 15418.931902608252 23217.71222348806 1.0750377839314735 0.7775573219910176 0.8868436607106436 1.005309178807594 0.9121284308642578 0.7410417423485341 0.5926670807155908 0.6553887737972961 0.6641021197174536 1.0 14.502938201604996 -6.801743056979923 4.165758559239095 0.6958951724120415 0.9259824861453357 0.37891169267800906 0.12576046467029633 0.20186834537033338 7.498294032140547 0.04329698225965869 0.03929347048849576 1.578544913012305e-07 6.801743056979923 0.23008731373329427 FRELAEEAAR ddPTM_PC-9_AZD4547_30min_R2 1 FRELAEEAAR 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 108.31 0.0026521 4009800.0 16952.0 18065.0 22602.0 31942.0 32715.0 28012.0 17061.0 19836.0 19116.0 23773.0 False True 22342.38337649554 23904.157969670865 22302.282712115535 24578.26539898055 28173.08695200541 26260.40521177965 18579.39594846357 16770.80198593395 20126.43273391254 22940.714505938045 0.9739183742822121 1.0419970992395828 0.9721703614045126 1.0713818609537482 1.228082366166625 1.1447073806259314 0.8098874140844402 0.7310496794506093 0.8773237088453785 1.0 14.485622705433292 -7.268677063960609 24.865660345577094 0.8321526579732362 1.0732001837642573 0.5504055122776371 0.09543234820550707 396.2007811821801 1361174.3941627657 0.041745649331107096 0.02880423639612819 5.3867018215906714e-08 7.268677063960609 0.24104752579102107 FRELAEEAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FRELAEEAAR 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 72.096 0.040773000000000004 3937400.0 14781.0 10868.0 16513.0 20677.0 22108.0 18682.0 19178.0 14548.0 20905.0 14131.0 False True 17283.131361942735 11946.903215890195 16906.73254590123 19518.534725738467 17776.09610360591 17702.283032218613 17361.321003303845 14166.130414880148 21210.696076625554 16692.83843906555 1.035362046127263 0.7156903398724186 1.0128135252501524 1.1692759620832405 1.0648935571080145 1.0604717164691837 1.040046069257693 0.848635207642563 1.2706464603998715 1.0 14.026941670007199 -5.503247367936741 24.110812355287614 1.0599247332438402 0.8727075648022006 0.2628175278202344 0.12495063574489904 583.1991852263753 716269.7812169166 0.03109402528414311 0.06319225008227446 3.138720414296876e-06 5.503247367936741 -0.1872171684416396 FRELAEEAAR ddPTM_PC-9_Lapatinib_30min_R1 2 FRELAEEAAR 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 140.78 5.6124e-06 2540100.0 39640.0 27906.0 39248.0 28404.0 28418.0 29354.0 24215.0 29109.0 33976.0 25398.0 False True 39074.726330914316 27841.385371539545 36021.18094166122 30492.924912966326 26746.50911193764 28098.597847516136 25468.734215095028 30461.510407629015 30149.26509685877 29788.010459292265 1.3117601923872393 0.9346507182675747 1.2092509834078073 1.023664368408806 0.8978951161739693 0.9432854834637295 0.8549995055863204 1.0226097660754196 1.012127518152318 1.0 14.86244414877757 -1.5228787463970193 0.6300870025822047 0.9604342504317224 23.81568181985576 0.4731405812169076 0.09649068067697497 185.2443340204483 1.2881213453999756 0.04213117964832495 5877.405630595053 0.029999999922862362 1.5228787463970193 22.85524756942404 FRIDELEPR ddPTM_PC-9_AZD4547_30min_R2 3 FRIDELEPR 9 1 F5H6X6;Q14697;Q14697-2 F5H6X6 GANAB Neutral alpha-glucosidase AB 0 ;; 142.36 1.0008e-08 11001700.0 46017.8 44526.1 57658.6 80501.0 69252.4 56988.0 49423.1 65725.7 51591.9 61608.2 False True 60650.50317029826 58918.291069657396 56894.00929054003 61942.73817805191 59637.89964343759 53424.53135116731 53821.66015476877 55569.30329133395 54318.94250704861 59451.31567007665 1.0201709160967347 0.9910342673763982 0.9569848648307749 1.0419069364553906 1.0031384330398403 0.8986265610612421 0.9053064603893799 0.9347026666275005 0.9136709910423179 1.0 15.859421117017304 -6.749818375720375 24.898064800570335 0.9248080740338642 1.0016462591717692 0.538677597745839 0.03318902966504647 153.36171944716236 328577.70671445766 0.010730808820407587 0.010644368192010577 1.779023251546038e-07 6.749818375720375 0.07683818513790497 FRIDELEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 FRIDELEPR 9 1 F5H6X6;Q14697;Q14697-2 F5H6X6 GANAB Neutral alpha-glucosidase AB 0 ;;; 126.31 0.0018127 11255200.0 71235.0 69276.0 82777.0 86997.0 85106.0 83654.0 84240.0 67046.0 75156.0 62498.0 False True 83293.67854461764 76153.26345086585 84750.71761352071 82122.84013807948 68430.0902385327 79267.03697554939 76260.1773552151 65286.113541109036 76255.01431881703 73828.39266610426 1.1282065820032274 1.0314901991064065 1.1479420660939168 1.112347664258216 0.9268804015280967 1.073666026213545 1.0329383398621288 0.8842954747284222 1.032868406924249 1.0 16.17188812918299 -6.241914353704387 24.646867451698004 0.9921422889145438 1.102813713971032 0.4764903672933509 0.05812069942305933 636.6783766952174 803692.6514265963 0.017183680677535507 0.02214963759386818 5.729090020178278e-07 6.241914353704387 0.11067142505648808 FRIDELEPR ddPTM_PC-9_Lapatinib_30min_R1 1 FRIDELEPR 9 1 F5H6X6;Q14697;Q14697-2 F5H6X6 GANAB Neutral alpha-glucosidase AB 0 125.71 0.0018376999999999998 5337900.0 49181.0 40968.0 39706.0 29991.0 36775.0 35830.0 37745.0 32947.0 37270.0 27233.0 False True 48479.6699213092 40873.141113066406 36441.52594959238 32196.638187043158 34611.9668024318 34297.63442380947 39699.251412296566 34477.83789893689 33072.26012950099 31940.187764308448 1.5178267040584774 1.2796775465027193 1.140930235554656 1.0080290831296015 1.0836494468297688 1.073808165340072 1.2429247976011737 1.0794500694032905 1.0354435100239947 1.0 14.963085173383142 -4.873316133173975 1.6952343990179695 1.0850831141781851 1.6196610606749218 0.8180743481702752 0.06491734333330457 0.32988456165946883 1.0962334897847763 0.01897070582173509 0.274193469240025 1.338701860080408e-05 4.873316133173975 0.5345779464967366 FRPFTFSQS(ph)TPIGLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FRPFTFSQSTPIGLDR 16 1 A0A0A0MRY4;Q96N96-6;J3KQJ8;Q96N96-5;Q96N96-4;Q96N96 A0A0A0MRY4 SPATA13 Spermatogenesis-associated protein 13 1 FRPFT(0.002)FS(0.121)QS(0.856)T(0.022)PIGLDR 65.28699999999999 0.013552000000000002 4613400.0 11898.0 11295.0 15094.0 10259.0 20140.0 12540.0 13909.0 15907.0 14396.0 10299.0 True False 13912.0964037883 12416.292953945504 15453.898204313778 9684.221490126756 16193.711576199705 11882.380324591655 12591.438827560385 15489.458104859657 14606.514265443737 12166.12717316085 1.143510683866527 1.0205624828036102 1.2702397389372957 0.795998706267898 1.3310490138492 0.9766773070402259 1.0349586724144884 1.2731626000943224 1.2005886554980714 1.0 13.57058236951721 -7.741843241182957 24.959172229661625 1.1776568087910413 1.0812891202315473 0.04350865743595722 0.15534849696725736 614.0304121531598 782078.4047825333 0.06856952631120034 0.03951904447680374 1.811994014769118e-08 7.741843241182957 -0.09636768855949396 FRS(ph)FSELPSCDGNESWAYR ddPTM_PC-9_AZD4547_30min_R2 2 FRSFSELPSCDGNESWAYR 19 1 Q8NEV8-2;Q8NEV8 Q8NEV8-2 EXPH5 Exophilin-5 1 FRS(0.943)FS(0.057)ELPSCDGNESWAYR;FRS(0.941)FS(0.059)ELPSCDGNESWAYR 104.16 0.00012481 12468400.0 9806.0 10894.099999999999 14849.5 25463.0 20465.8 18438.4 15672.1 19196.6 13813.0 19122.3 True False 12924.104022529209 14415.404779263292 14652.585927509064 19592.898749428397 17624.47693542266 17285.44393320283 17066.886539119398 16230.206563983653 14543.126980201594 18452.834097375126 0.7003858569544954 0.7812027520105354 0.7940561243973554 1.061782631656318 0.9551094884622466 0.9367365382459948 0.9248924283965206 0.8795508851560294 0.7881243013110014 1.0 14.171554790644112 -5.577822909560981 9.289795520189534 0.9306726368347045 0.7523761922565142 0.5768569501015925 0.07009748834959612 0.24435799890307558 38.90428370520827 0.019983525877642124 0.03468966243546675 2.6434864609664237e-06 5.577822909560981 -0.17829644457819027 FRS(ph)FSELPSCDGNESWAYR ddPTM_PC-9_Lapatinib_30min_R1 1 FRSFSELPSCDGNESWAYR 19 1 Q8NEV8-2;Q8NEV8 Q8NEV8-2 EXPH5 Exophilin-5 1 FRS(0.759)FS(0.217)ELPS(0.01)CDGNES(0.014)WAYR 73.688 0.0022238 4593700.0 7560.7 9527.2 9897.7 8346.3 10445.0 10743.0 8417.2 5928.1 11236.0 7391.6 True False 7452.883031537426 9505.140353749424 9083.94931222688 8960.114744440609 9830.645635660107 10283.546933156154 8853.001430324099 6203.541167593035 9970.48335967462 8669.228211312098 0.8596939485123352 1.0964229020233405 1.047838295498281 1.0335539134555192 1.1339701062238188 1.1862125073299608 1.0211983367529998 0.7155817122795666 1.1501004606920568 1.0 13.081687846128279 -7.534445139592812 24.9810402056664 0.9333826705500187 1.066344651017703 0.10990062250260069 0.12759708595179114 381.7134837673364 824411.4530785002 0.057594204760016636 0.03328466386579237 2.921156739628901e-08 7.534445139592812 0.13296198046768437 FRSLAEES(ph)QAVAQAVNR ddPTM_PC-9_Lapatinib_30min_R1 1 FRSLAEESQAVAQAVNR 17 1 H3BSQ8;Q96A99-2;Q96A99 H3BSQ8 PTX4 Pentraxin-4 1 FRS(0.028)LAEES(0.972)QAVAQAVNR 52.731 0.027794 5764200.0 16330.0 15601.0 24898.0 18346.0 15929.0 20129.0 15838.0 19451.0 21876.0 17409.0 True False 16097.131205444763 15564.876843022585 22850.982549059354 19695.226040461934 14992.087537618927 19268.129592990794 16658.014144070832 20354.764469366597 19412.094515507484 20418.12245396562 0.7883747020195957 0.7623069593257124 1.119151998455236 0.9645953532146004 0.7342539732250041 0.943677835042493 0.8158445607145186 0.9968969730325661 0.9507286754339772 1.0 14.317562589012503 -1.5228787914993465 0.06786220229013797 1.1093200271184853 0.44438125682470836 0.12867076189614024 0.11102516345137525 679.1614814347159 3.4255102628922245 6.058036727970981 43.41335335535243 0.02999999680730414 1.5228787914993465 -0.664938770293777 FRT(ph)PSFLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FRTPSFLK 8 1 P35611;P35611-3;P35612;Q9UEY8-2;Q9UEY8 P35611;Q9UEY8-2 ADD1;ADD2;ADD3 Alpha-adducin;Beta-adducin;Gamma-adducin 1 FRT(0.997)PS(0.003)FLK 64.73 0.038718 2976500.0 19467.0 28896.0 22768.0 19320.0 25167.0 14792.0 20475.0 11421.0 15506.0 11842.0 True False 22762.378609223957 31764.603912988874 23310.875468120837 18237.56303628511 20235.70701282114 14016.28148017223 18535.459773837018 11121.21085154977 15732.745915530048 13988.860858779584 1.6271788560208607 2.2707069741888963 1.666388400274254 1.3037203829816484 1.4465586023840504 1.001960175433115 1.3250156650320766 0.7950047515534446 1.1246624063499766 1.0 13.771990865261422 -5.937991272203319 0.9431881265470323 1.0399374758976792 2.0024440438642723 0.7041189295346946 0.22020045243306907 0.3293231981336193 0.5828624719319665 0.09167870016551194 0.22128276537482772 1.1534764384211055e-06 5.937991272203319 0.9625065679665932 FRTPS(ph)FLK ddPTM_PC-9_AZD4547_30min_R2 1 FRTPSFLK 8 1 P35611;P35611-3;P35612;Q9UEY8-2;Q9UEY8 P35611;Q9UEY8-2 ADD1;ADD2;ADD3 Alpha-adducin;Beta-adducin;Gamma-adducin 1 FRT(0.394)PS(0.606)FLK 68.786 0.020122 11004000.0 19623.0 20944.0 22881.0 27851.0 25096.0 28376.0 22855.0 27753.0 21078.0 22776.0 True False 25862.70581624422 27713.738417757348 22577.582989820192 21430.38224366061 21611.853588492344 26601.64423423742 24889.05072399829 23464.41155049531 22192.14004841015 21978.619172474868 1.17672114036325 1.2609408352852718 1.0272521131853198 0.9750558975287743 0.9833126193641024 1.2103419248262985 1.132421037403857 1.067601716302596 1.0097149358774407 1.0 14.423813130004032 -5.264172614530312 24.982798899362468 1.0566369236004038 1.2188309934498704 0.46677101252609854 0.0716519153565592 212.33649268025044 1940855.2108359968 0.02041593702970242 0.045828518754493765 5.442862780146645e-06 5.264172614530312 0.1621940698494666 FRTPS(ph)FLK ddPTM_PC-9_Lapatinib_30min_R1 1 FRTPSFLK 8 1 P35611;P35611-3;P35612;Q9UEY8-2;Q9UEY8 P35611;Q9UEY8-2 ADD1;ADD2;ADD3 Alpha-adducin;Beta-adducin;Gamma-adducin 1 FRT(0.244)PS(0.756)FLK 64.82 0.025227 9965400.0 14251.0 17051.0 17936.0 15965.0 17688.0 16250.0 19928.0 17280.0 15600.0 13152.0 True False 14047.778126686671 17011.519457110324 16461.37131496218 17139.119357678755 16647.626615945996 15555.025380600155 20959.774331547127 18082.89188374145 13842.963724717343 15425.305676061578 0.9106969042751171 1.1028319188196303 1.0671666196222267 1.1111040336968383 1.0792412782964378 1.0084095386673528 1.3587915060947189 1.1722874258371527 0.8974190862356873 1.0 13.913011458419676 -4.760847318549087 24.71652617690901 1.0996485952397688 0.9106966574014029 0.17049793372476452 0.11541036767427752 21.742147369208965 906778.5755251126 0.028902386337210484 0.16674315617258917 1.734413644570209e-05 4.760847318549087 -0.18895193783836584 FS(ph)CDIEQLK ddPTM_PC-9_AZD4547_30min_R2 2 FSCDIEQLK 9 0 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;Q9NUQ6-2 B8ZZZ7 SPATS2L SPATS2-like protein 1 FS(1)CDIEQLK;FS(1)CDIEQLK 73.435 0.029601 6989900.0 20188.2 16874.0 21940.0 23142.0 19443.2 24345.0 22796.0 22453.0 21152.8 23783.0 True False 26607.627659353893 22328.190510945267 21649.06126465866 17806.969440335848 16743.84729406178 22822.70330146991 24824.799838296425 18983.404768611363 22270.893823702925 22950.364408981808 1.1593553455273584 0.9728904566851649 0.9432992382546278 0.7758904879683283 0.7295678184311941 0.9944375128326094 1.0816734495327247 0.8271504726601228 0.970393908646916 1.0 14.486229440676858 -4.733025935299866 2.071924799392949 0.9066629537298111 1.2508276669170573 0.33271571043617354 0.10346224551218568 1.0245715645309397 4.425913058366478 0.029593480522166964 0.701073335902308 1.849158187217812e-05 4.733025935299866 0.3441647131872462 FS(ph)CDIEQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FSCDIEQLK 9 0 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;Q9NUQ6-2 B8ZZZ7 SPATS2L SPATS2-like protein 1 FS(1)CDIEQLK 105.2 0.0026519 3481700.0 8510.1 9322.3 10967.0 10675.0 11425.0 8987.0 12908.0 9330.0 9814.7 7375.3 True False 9950.691847863405 10247.75633506562 11228.494872579118 10076.914358816959 9186.353265048732 8515.70589929069 11685.260794172806 9085.097385952138 9958.221419911823 8712.383507157327 1.1421319825612353 1.1762287928035957 1.2887971315030813 1.156619695464353 1.0544018473821812 0.9774255107451292 1.3412243371257964 1.0427797833381212 1.142996220463783 1.0 13.088851745569116 -14.522878578726408 0.09470677350606628 0.534439359234444 1.256061917264344 0.17538901539488194 0.10211141676434606 372.04360309243293 2.4157215785878665 34.67655457640977 2.112933640236865 3.000001150514009e-15 14.522878578726408 0.7216225580298999 FS(ph)CDIEQLK ddPTM_PC-9_Lapatinib_30min_R1 2 FSCDIEQLK 9 0 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;Q9NUQ6-2 B8ZZZ7 SPATS2L SPATS2-like protein 1 FS(1)CDIEQLK;FS(1)CDIEQLK 111.63 0.0022221 8392800.0 18805.2 26431.0 28570.0 22767.5 27382.0 27878.0 25211.0 22299.4 25761.0 20437.9 True False 18537.03439954868 26369.800643415794 26221.084883389267 24441.89790015353 25771.44459508329 26685.72292679206 26516.302221629598 23335.51153196204 22859.52490464383 23970.563783210084 0.7733249233183552 1.1000909649812338 1.0938868655961915 1.0196630384335637 1.0751288467038316 1.1132705583455562 1.1062026934970401 0.9735069956221531 0.953649864533246 1.0 14.548976220855065 -4.755494962833178 24.99999327515738 1.052745583256062 0.7733244701027796 0.6870820737163192 0.05561602555903994 119.28078929314731 501600.81143460533 0.014803012099849086 0.13095886006705645 1.7559212601429645e-05 4.755494962833178 -0.27942111315328233 FS(ph)EGVLQSPSQDQEK ddPTM_PC-9_AZD4547_30min_R2 2 FSEGVLQSPSQDQEK 15 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 FS(0.998)EGVLQS(0.002)PS(0.001)QDQEK;FS(1)EGVLQSPSQDQEK 185.99 3.9733e-07 8254100.0 30953.0 25541.0 23795.0 33167.0 38408.0 28725.0 34744.0 49350.0 42933.0 36182.0 True False 40795.410137604216 33796.62876852272 23479.46275262321 25520.860575041876 33075.71217033848 26928.82120906648 37836.148691953495 41724.091450183536 45202.35073054334 34915.2791929437 1.168411396975135 0.9679610058897351 0.6724695690638601 0.7309367464602599 0.9473134093403728 0.7712618037580731 1.0836559112951356 1.1950095320622807 1.2946295082090775 1.0 15.091570888535813 -7.442666379648063 4.283184439844137 1.1782170107900543 0.8687086693207857 0.44233556874737257 0.148070728537828 0.2095584296759091 7.049099323256328 0.06966338448530757 0.044531760348922436 3.6085574207729384e-08 7.442666379648063 -0.30950834146926853 FS(ph)EGVLQSPSQDQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FSEGVLQSPSQDQEK 15 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 FS(1)EGVLQSPSQDQEK;FS(1)EGVLQSPSQDQEK;FS(1)EGVLQSPSQDQEK 188.04 1.7449e-20 6955000.0 53401.0 51114.0 36042.0 41638.0 48231.0 33234.9 22476.199999999997 41196.0 27936.9 23213.5 True False 62440.73458217335 56188.26011934227 36901.37797004619 39305.15785221736 38780.48177913048 31492.003337302333 20347.091622403685 40114.648650769996 28345.42431107775 27421.923792035093 2.2770369816398417 2.0490269225991566 1.345688882001943 1.4333479354075749 1.4142144830259709 1.1484242891247995 0.7420008813646274 1.4628677752514796 1.0336774518828944 1.0 14.743042166854423 -4.102075996083829 0.5370203617956764 1.078674589457575 4.44266455063406 0.8017507886560062 0.19853505724322415 3.4774888928948324 0.4447485941632867 0.1092494001937457 8.572956722155524 7.905402812679632e-05 4.102075996083829 3.3639899611764847 up FS(ph)EGVLQSPSQDQEK ddPTM_PC-9_Lapatinib_30min_R1 4 FSEGVLQSPSQDQEK 15 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 FS(0.997)EGVLQS(0.002)PS(0.001)QDQEK;FS(1)EGVLQSPSQDQEK;FS(0.999)EGVLQSPS(0.001)QDQEK;FS(1)EGVLQSPSQDQEK 195.28 1.2290999999999998e-09 15064400.0 80104.0 62102.2 64187.0 61523.0 51153.0 40023.1 37440.1 41269.9 43367.8 56219.0 True False 78961.70227072565 61958.40617144776 58909.792628985146 66047.6066547116 48144.281110667434 38311.40531140294 39378.565182183724 43187.45021717714 38483.26168082032 65936.37924289134 1.1975438017282178 0.9396695251222419 0.8934338419156714 1.001686889894432 0.7301626456211259 0.5810359281372479 0.597220618334592 0.6549866812990526 0.583642324960833 1.0 16.00878704617945 -6.333280036742715 3.5021429427282915 0.6560050367188239 0.9979268028114803 0.5587267202212779 0.13702938932936798 0.17273785735152075 4.149487460823709 0.04234903748150338 0.04969151183532705 4.6421584840460576e-07 6.333280036742715 0.34192176609265634 FS(ph)GGFGAR ddPTM_PC-9_AZD4547_30min_R2 3 FSGGFGAR 8 0 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDT5;A0A2R8Y7T2;O15523-2;O15523;A0A0J9YVQ7;A0A087WVZ1 A0A2R8Y5G6 DDX3X;DDX3Y ATP-dependent RNA helicase DDX3X;ATP-dependent RNA helicase DDX3Y 1 FS(1)GGFGAR;FS(1)GGFGAR;FS(1)GGFGAR 93.598 0.007104899999999999 96061600.0 40669.8 47839.7 85084.0 105974.0 108970.0 95295.0 80036.0 107994.0 79405.0 98407.0 True False 53601.95041560867 63302.947468677696 83955.7305671019 81543.33158197875 93841.39645911733 89336.18858548287 87159.04894972336 91306.0087552404 83602.18619147968 94961.8008827596 0.5644580233033486 0.6666148586085882 0.8841000253433918 0.8586961370146363 0.9882015251055997 0.9407592079659257 0.9178327299977223 0.9615024979145808 0.8803770085899637 1.0 16.535059674470197 -5.102519944429201 1.3269128771389949 0.9408449112259774 0.4967320660880235 0.9126470320977407 0.039823769232401045 0.19607190422653356 0.45422007320494034 0.011490916398128086 0.10077989676092154 7.897325810891427e-06 5.102519944429201 -0.44411284513795385 FS(ph)GGFGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 FSGGFGAR 8 0 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDT5;A0A2R8Y7T2;O15523-2;O15523;A0A0J9YVQ7;A0A087WVZ1 A0A2R8Y5G6 DDX3X;DDX3Y ATP-dependent RNA helicase DDX3X;ATP-dependent RNA helicase DDX3Y 1 FS(1)GGFGAR;FS(1)GGFGAR;FS(1)GGFGAR;FS(1)GGFGAR;FS(1)GGFGAR;FS(1)GGFGAR 92.051 0.0082649 84641200.0 71695.9 100744.0 120815.0 122654.0 144639.0 109546.0 123597.0 109862.0 105166.0 78896.9 True False 83832.5998114274 110745.19852609871 123695.68779343924 115782.09402963352 116298.02624974932 103801.21491528845 111888.99739521061 106978.23890841105 106703.85379547498 93200.28342248306 0.899488678928246 1.1882495895863685 1.327202914531048 1.2422933684094672 1.247829105009935 1.1137435542416827 1.2005220723204282 1.1478316908487456 1.1448876535254655 1.0 16.508046721677815 -9.025497906852431 0.8768201218009911 0.9991504144301284 1.184664177587657 0.18091651080175708 0.10711995346293238 2.9729943613404246 3.536211957719995 0.11172209110578299 0.036030610099585435 9.429791562788053e-10 9.025497906852431 0.18551376315752854 FS(ph)GGFGAR ddPTM_PC-9_Lapatinib_30min_R1 3 FSGGFGAR 8 0 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDT5;A0A2R8Y7T2;O15523-2;O15523;A0A0J9YVQ7;A0A087WVZ1 A0A2R8Y5G6 DDX3X;DDX3Y ATP-dependent RNA helicase DDX3X;ATP-dependent RNA helicase DDX3Y 1 FS(1)GGFGAR;FS(1)GGFGAR;FS(1)GGFGAR 72.607 0.032219 100706900.0 53983.0 73361.0 67686.0 62150.0 70150.0 56361.0 57147.0 52515.0 59177.0 52176.0 True False 53213.19252073023 73191.13711178649 62121.11835551575 66720.71832632227 66023.91492020644 53950.571413908016 60105.792037581465 54955.03861543297 52511.863098564034 61194.55207985008 0.8695740178193423 1.1960400823962662 1.015141319679187 1.0903048728792284 1.0789181826848695 0.8816237651925336 0.98220821943679 0.8980380891378134 0.8581133665304652 1.0 15.901115600486458 -6.756560711389923 24.99971203303107 0.9212622839591594 1.0584123323590864 0.3470875613163138 0.08597890692256473 125.68935747537229 644068.3827382053 0.02715935988802855 0.026341576940764014 1.7516175529723217e-07 6.756560711389923 0.13715004839992695 FS(ph)LCSDNLEGISEGPSNR ddPTM_PC-9_AZD4547_30min_R2 2 FSLCSDNLEGISEGPSNR 18 0 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;H0Y7I9;C9IZ08;B4DGD8;A0A0A0MQV8 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 FS(0.99)LCS(0.01)DNLEGISEGPSNR;FS(1)LCSDNLEGISEGPSNR 126.14 2.4405e-05 2379800.0 11300.0 14038.6 15093.599999999999 17022.6 19119.2 21672.4 14963.6 17562.7 16807.6 18307.7 True False 14893.164945398756 18576.302910214294 14893.449002016956 13098.302566548318 16464.829101414685 20317.22140196248 16295.33141166575 14848.788265696821 17696.01542260453 17666.75299543019 0.843005217158531 1.0514837058637416 0.8430212957564643 0.7414097298997965 0.9319669044828779 1.1500257804712546 0.9223727425113611 0.8404933419025962 1.001656355708483 1.0 14.108749288264963 -6.518936660087069 24.996079394972114 0.9771390704391243 0.8752900873438944 0.2135962654554927 0.10185119967629114 316.82857956133745 2008971.027881454 0.035304491573013984 0.03609207674468302 3.0273549221168473e-07 6.518936660087069 -0.10184898309522994 FS(ph)LCSDNLEGISEGPSNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FSLCSDNLEGISEGPSNR 18 0 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;H0Y7I9;C9IZ08;B4DGD8;A0A0A0MQV8 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 FS(0.997)LCS(0.003)DNLEGISEGPSNR 106.31 0.0033792 0.0 2906.0 3852.8 3890.6 4008.4 5499.2 3270.2 3656.1 3163.9 3861.7 3184.0 True False 3397.9284038837445 4235.280521731852 3983.3666591826636 3783.8223434081397 4421.671236337505 3098.7049551419177 3309.7677401282285 3080.8509774291515 3918.1700568813603 3761.2339954698705 0.9034078730481271 1.126034840382953 1.0590584536831091 1.0060055683760902 1.1755905752375637 0.8238532776408167 0.8799685805548392 0.819106437179875 1.0417246205900796 1.0 11.876990347382447 -6.77156705156973 24.999030364854736 0.8995646146939186 1.0556328311892813 0.35731538935713214 0.09374426559263599 207.6344617365927 512519.38939347974 0.031510539765859796 0.028103862278580482 1.69212697349338e-07 6.77156705156973 0.15606821649536273 FS(ph)LCSDNLEGISEGPSNR ddPTM_PC-9_Lapatinib_30min_R1 2 FSLCSDNLEGISEGPSNR 18 0 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;H0Y7I9;C9IZ08;B4DGD8;A0A0A0MQV8 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 FS(1)LCSDNLEGISEGPSNR;FS(0.997)LCS(0.002)DNLEGISEGPSNR 156.08 1.459e-05 2124000.0 14982.8 12706.2 16356.0 15342.7 17821.6 21035.7 18085.7 22159.8 23595.8 16201.7 True False 14769.142524490979 12676.779574566595 15011.272815985823 16471.053339746824 16773.36852661369 20136.052147611746 19022.089051990264 23189.425206327185 20938.19252921061 19002.14225759176 0.7772356571317843 0.6671237065127198 0.789977919988916 0.8667998121720348 0.8827093439905372 1.0596727397705363 1.0010497129285796 1.22035846758607 1.1018858950414054 1.0 14.213874453378434 -6.44598237569962 0.9154145597766912 1.1124642589482852 0.7206179642565645 0.819859465685266 0.06823255884292351 0.21495905538696175 0.391933091658144 0.03522481555793969 0.04589482917076016 3.5811096947064003e-07 6.44598237569962 -0.3918462946917206 FS(ph)MPGFK ddPTM_PC-9_AZD4547_30min_R2 1 FSMPGFK 7 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 FS(1)MPGFK 72.87899999999999 0.037712999999999997 3237000.0 21641.0 28980.0 28634.0 20740.0 35026.0 31973.0 31555.0 53317.0 42056.0 34329.0 True False 28522.387839236682 38347.21826521237 28254.294450876754 15958.71342980578 30163.244492769085 29973.72325561295 34363.333869865055 45078.08275277478 44278.99430097433 33127.1521589344 0.8609972780755375 1.1575766634340803 0.8529044185664045 0.4817411817725996 0.9105293551360724 0.9048083309971163 1.0373162686910067 1.3607593715422115 1.3366375137994553 1.0 15.015726564170368 -7.484117600690638 2.78164041853508 1.2597210502946778 0.8584087382759104 0.45611673093904037 0.179948753283346 0.24978652487576558 3.848688085760023 0.09776940958772407 0.05608160052391707 3.280064616609202e-08 7.484117600690638 -0.4013123120187675 FS(ph)PDSQYIDNR ddPTM_PC-9_AZD4547_30min_R2 2 FSPDSQYIDNR 11 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 FS(0.996)PDS(0.004)QYIDNR;FS(0.997)PDS(0.003)QYIDNR 149.82 7.6252e-05 59785000.0 63694.0 58759.0 79112.0 74299.0 69785.0 76321.0 79181.0 83451.0 59804.0 46558.0 True False 83947.36708249793 77751.69765512817 78062.92318913755 57170.51345810711 60096.5573267827 71548.63580494908 86227.95560607781 70555.5654632069 62965.1173477142 44928.018591152286 1.868485851700341 1.7305837224355112 1.7375109260774424 1.2724913150157429 1.3376186889892707 1.5925170539134172 1.9192467932039798 1.5704134674904509 1.4014665975079075 1.0 15.455327817289907 -12.248497764192404 0.2568415100067646 1.903605612192295e-14 1.6687434322945203 0.47160876320402234 0.19959677152860436 52.5900632503779 1.4667378199862595 29.46038138171797 0.3202121573824069 5.64289846379199e-13 12.248497764192404 1.6687434322945012 FS(ph)PDSQYIDNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 FSPDSQYIDNR 11 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 FS(0.601)PDS(0.399)QYIDNR;FS(1)PDSQYIDNR;FS(0.957)PDS(0.043)QYIDNR;FS(0.999)PDS(0.001)QYIDNR 172.58 0.00020818 51525100.0 90199.0 150332.0 147768.0 106230.0 143252.0 95716.0 141178.0 87686.0 96339.0 91209.0 True False 105467.90918854432 165255.96745042346 151291.3495332609 100278.27750230688 115182.79894308641 90696.48446161205 127804.59779979277 85384.33541099657 97747.77561951814 107744.46968995329 0.978870743826017 1.5337767954677015 1.4041681208197376 0.9307046365430058 1.0690367614647671 0.8417739186298961 1.1861824385749424 0.7924707008786577 0.9072184948406007 1.0 16.71725429497497 -5.765732559917535 24.99999762270927 0.9613176578058148 1.3284224085545302 0.4690589271591551 0.16745807158296894 84.4045834015877 491507.7955741629 0.04531916376889663 0.06996444767434777 1.7150130935430852e-06 5.765732559917535 0.3671047507487154 FS(ph)PDSQYIDNR ddPTM_PC-9_Lapatinib_30min_R1 2 FSPDSQYIDNR 11 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 FS(0.996)PDS(0.004)QYIDNR;FS(1)PDSQYIDNR 147.7 0.00011454 58054000.0 58116.0 90148.0 106864.0 85400.0 97292.0 84989.0 107977.0 87254.0 91500.0 79621.0 True False 57287.25518283087 89939.26784467648 98078.05442696922 91680.60088604844 91569.47584343157 81354.2185890354 113567.52072448129 91308.13937638747 81194.30646228438 93383.38376168611 0.6134630474413696 0.9631185358864378 1.0502730836704728 0.9817656760009558 0.9805756886805085 0.8711851649823583 1.2161427027993008 0.9777771558311202 0.869472739063427 1.0 16.51087824535977 -4.763780956416469 4.660068515511739 0.9960613874121919 0.5847465862024858 0.6049991275061063 0.09154661500951629 0.12916298382014788 6.548035841768053 0.022823332646786317 0.1768323921841217 1.7227372468417518e-05 4.763780956416469 -0.4113148012097061 FS(ph)PEVPGQK ddPTM_PC-9_AZD4547_30min_R2 2 FSPEVPGQK 9 0 P46821;D6RA32;D6RGJ3 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 FS(1)PEVPGQK;FS(1)PEVPGQK 82.494 0.015693000000000002 7840000.0 81148.0 85952.0 94846.0 94708.0 102463.0 123395.0 114047.0 117476.0 102341.0 110377.0 True False 106951.37601674497 113734.3031170302 93588.28006872456 72874.53382401378 88237.7810901218 115679.09114335076 124196.9620616862 99322.78352992417 107750.5363267077 106512.73482614387 1.0041182041876688 1.0678000457191694 0.8786581268567055 0.6841861111064674 0.8284247065306183 1.0860587828504145 1.1660292289406287 0.9324967919755741 1.0116211596912261 1.0 16.70066640603497 -6.765657877624655 24.99441585357215 1.0429465048758941 0.8900114335142667 0.30371267391558543 0.11088187864062492 154.38795392623103 914735.2619499019 0.04357845053468454 0.03979271582828319 1.715308036556819e-07 6.765657877624655 -0.15293507136162743 FS(ph)PEVPGQK ddPTM_PC-9_Lapatinib_30min_R1 1 FSPEVPGQK 9 0 P46821;D6RA32;D6RGJ3 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 FS(1)PEVPGQK 70.808 0.036675 4344400.0 47260.0 56699.0 61226.0 61122.0 60504.0 60616.0 57902.0 52197.0 63201.0 50343.0 True False 46586.063733577445 56567.7169490762 56192.23461919465 65617.1157770148 56945.27367544075 58023.59498279751 60899.88224333812 54622.2631745169 56082.63784396549 59044.72047216909 0.7889962618340438 0.9580486874476707 0.9516894003364964 1.1113121588566692 0.9644431071916427 0.9827058967981247 1.0314196046036574 0.9250998690096818 0.9498332348003953 1.0 15.849520445283002 -4.629987168744383 2.054451092720096 0.9913927856598614 0.6660514012876375 0.593415228208069 0.0495410273960344 0.8789448584054371 2.870663816107413 0.013479175085031282 0.6183625788620517 2.344298076719183e-05 4.629987168744383 -0.32534138437222393 FS(ph)PGAPGGSGSQPNQK ddPTM_PC-9_AZD4547_30min_R2 2 FSPGAPGGSGSQPNQK 16 0 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 FS(1)PGAPGGSGSQPNQK;FS(1)PGAPGGSGSQPNQK 244.05 7.252700000000001e-47 37988000.0 73839.0 72988.0 74940.0 67201.0 65097.0 66185.0 71274.0 86970.0 77116.0 63954.0 True False 97318.26605338916 96579.9436418675 73946.24663507381 51708.84769510018 56059.4052060124 62046.44148727817 77617.24792396654 73530.78487178257 81192.19432456576 61714.9899260826 1.5768983543536081 1.5649349332721827 1.1981893981290583 0.8378652861652088 0.9083596266183627 1.0053706816057584 1.2576725365576569 1.1914574556335829 1.3155992477971954 1.0 15.9133333270353 -5.328867024028527 3.7892609793984975 1.0765053221619723 1.5786697105750547 0.653926928055296 0.14216520816347447 0.14697552117716056 4.130903332696458 0.04286762782001533 0.10221498420811002 4.689569493848634e-06 5.328867024028527 0.5021643884130824 FS(ph)PGAPGGSGSQPNQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 FSPGAPGGSGSQPNQK 16 0 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 FS(1)PGAPGGSGSQPNQK;FS(1)PGAPGGSGSQPNQK;FS(1)PGAPGGSGSQPNQK;FS(1)PGAPGGSGSQPNQK;FS(1)PGAPGGSGSQPNQK 256.98 2.0069e-57 159544200.0 195462.0 250890.0 211123.0 179887.0 195328.0 140422.0 185316.0 139880.0 133523.0 120299.0 True False 228549.8560495263 275796.7011257535 216156.9730084366 169808.51459152254 157054.8805737801 133058.02312119695 167761.5269083459 136208.2982151112 135475.52127430137 142108.25641363976 1.6082799255820703 1.940750721217646 1.5210725855312761 1.1949236369296843 1.105177732366476 0.9363145145761274 1.1805192121985948 0.9584826501469743 0.9533261802886932 1.0 17.116630851262272 -5.729462171308291 1.9595484327175818 1.0247039004337712 1.7826049676386306 0.8923717597113232 0.1058336079278029 0.0919603646734689 0.7186717661161257 0.031075367440928137 0.06397988301979707 1.8643945669972708e-06 5.729462171308291 0.7579010672048594 FS(ph)PGAPGGSGSQPNQK ddPTM_PC-9_Lapatinib_30min_R1 2 FSPGAPGGSGSQPNQK 16 0 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 FS(1)PGAPGGSGSQPNQK;FS(1)PGAPGGSGSQPNQK 175.27 1.1631e-05 47806000.0 46818.0 78762.0 86216.0 74784.0 82023.0 80992.0 91285.0 85748.0 76227.0 70763.0 True False 46150.366734630334 78579.63142812281 79127.65328338438 80283.86483211086 77198.56840342254 77528.16096157333 96011.29063906461 89732.16511846414 67641.51255410443 82994.29026422948 0.5560667678186186 0.9468076801180938 0.9534108073153603 0.9673420252948797 0.9301672218371281 0.9341384897050918 1.1568421192999279 1.0811847999757964 0.8150140490237785 1.0 16.34072446672193 -4.752852394647782 3.988899200881544 0.9835874525152891 0.5038802596840839 0.6810389834763984 0.08645469241878595 0.1593995611972332 4.641151175030106 0.022555621571388268 0.23128081905034187 1.7666381528318077e-05 4.752852394647782 -0.4797071928312052 FS(ph)PPPVGGQGK ddPTM_PC-9_AZD4547_30min_R2 2 FSPPPVGGQGK 11 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 FS(1)PPPVGGQGK;FS(1)PPPVGGQGK 107.03 0.0023608 13994800.0 55452.0 67334.0 59018.0 48502.0 43830.0 72564.0 62702.0 72849.0 66763.0 57549.0 True False 73084.58252674794 89098.39871186372 58235.38275832385 37320.613248430076 37744.961060871065 68026.56160886693 68282.35653013096 61591.86095348364 70291.95588063408 55534.22702655233 1.3160277263210007 1.6043871227245765 1.048639476524631 0.6720290395072238 0.6796702336889326 1.2249483832077415 1.2295544601257062 1.1090792876982873 1.265741140990865 1.0 15.761089591401122 -5.281710906669817 17.663557927033736 1.0215789230956858 1.4602049554091152 0.40684102420269375 0.2082653748017686 17.793212286204238 15505.167219735638 0.060875659924952794 0.12765882759998154 5.227440440512954e-06 5.281710906669817 0.43862603231342945 FS(ph)PPPVGGQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FSPPPVGGQGK 11 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 FS(1)PPPVGGQGK 65.842 0.043687000000000004 7136900.0 30335.0 53099.0 35019.0 28885.0 38567.0 24332.0 42532.0 27551.0 31767.0 25723.0 True False 35470.116356439576 58370.317800934296 35853.985770297055 27266.667096433503 31010.073205526027 23055.987085962053 38503.06105498588 26827.815442697454 32231.532277740414 30386.376276844047 1.1673032688491256 1.920937109089096 1.1799362136385971 0.8973319769363904 1.020525544836265 0.7587606655003439 1.2671159174819788 0.8828895949380317 1.0607231340810608 1.0 14.891137016267434 -5.488453871819712 7.882783133813866 0.9868170652658652 1.5477664023703943 0.5280844182837942 0.20981918661036997 0.17881942583927646 35.996375469622485 0.050855647662820226 0.10335286315104594 3.247477331113646e-06 5.488453871819712 0.5609493371045291 FS(ph)PPPVGGQGK ddPTM_PC-9_Lapatinib_30min_R1 2 FSPPPVGGQGK 11 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 FS(1)PPPVGGQGK;FS(1)PPPVGGQGK 83.137 0.013166999999999998 14383400.0 50871.0 89145.0 69016.0 64143.0 97622.0 103765.0 115169.0 118120.0 83949.0 96734.0 True False 50145.57021140116 88938.59022955252 63341.77088946419 68860.29019477546 91880.06589223663 99327.21283802923 121131.88729375518 123608.28641826035 74493.77959783952 113454.34301004722 0.4419889876490704 0.7839152549821415 0.5583018614268015 0.6069427433789588 0.8098417694252565 0.8754818035412983 1.0676707835065253 1.0894980583274272 0.6565969853727198 1.0 16.79175231058794 -6.517832528383341 1.9936087906354611 0.9574312252757688 0.6050255761011518 0.5784058361430768 0.13692909902036263 0.23998036526723074 1.9188697572876 0.04985332187903405 0.05416657832417812 3.0350613317773435e-07 6.517832528383341 -0.35240564917461703 FS(ph)PTMGR ddPTM_PC-9_AZD4547_30min_R2 2 FSPTMGR 7 0 H0Y3P2;D3DQV9;P78344-2;P78344;H0YCH5 H0Y3P2 EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 1 FS(0.63)PT(0.37)MGR;FS(0.738)PT(0.262)MGR 88.177 0.017446 9606000.0 35383.0 45912.0 64901.0 69127.0 64141.0 78764.0 75714.0 94485.0 68407.0 65406.0 True False 46634.05798788001 60752.156141905776 64040.37033443989 53190.838151503594 55236.12930425118 73838.87462875251 82452.39932254692 79884.51429930262 72022.8543643416 63116.155848037015 0.7388608726450248 0.9625452520932521 1.0146430731400702 0.8427452121699185 0.8751504042363044 1.1698886542857947 1.3063596509436541 1.265674584042132 1.1411159852280768 1.0 15.945721718806707 -6.793975416498291 5.870811078058562 1.2039674211541236 0.8951838768535193 0.6588720132104093 0.10337967422704407 0.10666801537105089 10.11360406153633 0.03618573995249503 0.03265450818242926 1.6070322174685366e-07 6.793975416498291 -0.3087835443006043 FS(ph)PTMGR ddPTM_PC-9_Lapatinib_30min_R1 4 FSPTMGR 7 0 H0Y3P2;D3DQV9;P78344-2;P78344;H0YCH5 H0Y3P2 EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 1 FS(0.618)PT(0.382)MGR;FS(0.643)PT(0.357)MGR;FS(0.633)PT(0.367)MGR;FS(0.643)PT(0.357)MGR 98.58200000000001 0.012116 47898000.0 109437.0 176201.0 167972.0 159401.0 179480.0 174283.0 173723.0 174612.0 156175.0 121294.0 True False 107876.40831171232 175793.01741025734 154161.9905506706 171123.8812861477 168923.33927125673 166829.32236351605 182717.52690683262 182725.110972446 138584.92690434176 142259.50628590432 0.7583072029992077 1.235720705068099 1.083667408776503 1.2028994459058049 1.1874309399876946 1.1727112424264488 1.2843959020890898 1.2844492135746375 0.9741698851802731 1.0 17.118165536200934 -4.756006700641387 24.997586493049226 1.1716215216672488 0.7583065508812156 0.5711866037004253 0.10342308813030945 118.0026515410482 542912.1900253451 0.024523069663423033 0.20645027490074666 1.7538534417843397e-05 4.756006700641387 -0.4133149707860332 FS(ph)PVLGR ddPTM_PC-9_AZD4547_30min_R2 6 FSPVLGR 7 0 F8VZ44;Q9NRG9-2;Q9NRG9 F8VZ44 AAAS Aladin 1 FS(1)PVLGR;FS(1)PVLGR;FS(1)PVLGR;FS(1)PVLGR;FS(1)PVLGR;FS(1)PVLGR 90.601 0.015819 357994600.0 329724.0 315110.0 384915.0 481708.0 377250.0 390083.0 338859.0 458098.0 331330.0 352921.0 True False 434569.3733147475 416963.14518809743 379810.7756010065 370657.662914411 324875.3493090025 365691.04834451736 369016.7945431336 387309.4801448061 348843.42737639876 340565.34321079147 1.2760234767804095 1.224326413419054 1.1152361306650167 1.0883599000999757 0.9539295638426788 1.0737764591571328 1.0835418280207456 1.1372545323999175 1.0243068895019174 1.0 18.377572104632776 -5.280317817704613 1.71910973425882 1.0548953080425205 1.2811759091269421 0.734154993036203 0.047861434626851884 0.2426976317996121 1.2375176433585144 0.014594156797327089 0.06463748651485415 5.2442354543062666e-06 5.280317817704613 0.2262806010844216 FS(ph)PVLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 FSPVLGR 7 0 F8VZ44;Q9NRG9-2;Q9NRG9 F8VZ44 AAAS Aladin 1 FS(1)PVLGR;FS(1)PVLGR;FS(1)PVLGR;FS(1)PVLGR;FS(1)PVLGR;FS(1)PVLGR;FS(1)PVLGR 93.14299999999999 0.014112999999999999 302030800.0 255851.3 249572.4 264407.0 289737.0 314024.9 239972.0 285486.1 245873.8 260305.9 217024.6 True False 299161.8717964834 274348.29850546934 270711.4656491314 273503.97523002845 252493.975091607 227387.4458734378 258442.78986762444 239419.87327482505 264112.3813371189 256369.4420142121 1.1669170453626023 1.0701287031324918 1.055942796934918 1.066835318129945 0.9848832727794825 0.8869522205412934 1.0080873439405365 0.933886158169945 1.0302022708403662 1.0 17.96786478443613 -5.435778255300821 0.8389011686815399 0.968489692612976 1.1655682917554409 0.630035000397428 0.04493543424025565 0.731350201850485 0.7380038757899181 0.018839775700156623 0.11237053239450745 3.6662472033045324e-06 5.435778255300821 0.19707859914246484 FS(ph)PVLGR ddPTM_PC-9_Lapatinib_30min_R1 6 FSPVLGR 7 0 F8VZ44;Q9NRG9-2;Q9NRG9 F8VZ44 AAAS Aladin 1 FS(1)PVLGR;FS(1)PVLGR;FS(1)PVLGR;FS(1)PVLGR;FS(1)PVLGR;FS(1)PVLGR 96.948 0.012642 299865200.0 430365.0 447881.0 472488.0 404899.0 435389.0 428454.0 379433.0 369720.0 422091.0 273893.0 True False 424227.9161807258 446843.95906222553 433641.860496424 434676.62316346803 409780.2750277088 410130.02119505545 399078.1841600725 386898.5409292171 374550.6667647227 321235.0401105178 1.3206153227704371 1.3910187347821494 1.3499207942795832 1.353141995387308 1.2756400263393677 1.2767287810630938 1.2423245733802062 1.2044095214398418 1.1659707690539056 1.0 18.29326974411793 -8.305242833397688 0.3444128443710073 0.9713786877828428 1.3862653272027263 0.960110188356515 0.021689094195436503 0.24802394853317347 0.09145023781746801 0.038021128045664515 0.02531161288235571 4.9517323996005365e-09 8.305242833397688 0.4148866394198836 FS(ph)PVTPK ddPTM_PC-9_AZD4547_30min_R2 4 FSPVTPK 7 0 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 FS(0.998)PVT(0.002)PK;FS(1)PVTPK;FS(0.998)PVT(0.002)PK;FS(1)PVTPK 131.62 0.0043305 418930000.0 3236000.0 3588110.0 3854470.0 3337060.0 3391490.0 4160880.0 3851390.0 4233730.0 3658760.0 3753970.0 True False 4264980.68701862 4747896.3881846545 3803357.2093340424 2567752.3740630527 2920640.1548787076 3900699.515835705 4194156.2488689427 3579504.309936883 3852154.5840934226 3622544.652919542 1.1773438551216517 1.3106522743227333 1.0499131339261139 0.7088255963921953 0.8062399320667741 1.0767843848914294 1.1577928364495709 0.988118754327025 1.063383602735947 1.0 21.788572042446212 -5.415695521461391 5.264634394056104 0.9698451240417676 1.2389441596645931 0.41549288919045946 0.1270662301105641 0.2310285087834388 9.293684325641884 0.03767863601639361 0.08022654717217281 3.839763522621368e-06 5.415695521461391 0.26909903562282556 FS(ph)PVTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FSPVTPK 7 0 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 FS(0.986)PVT(0.014)PK;FS(0.998)PVT(0.002)PK;FS(1)PVTPK 91.265 0.015373 238621000.0 510950.0 595550.0 598610.0 593520.0 618020.0 474230.0 658700.0 506520.0 489500.0 401307.0 True False 597443.7432774944 654672.2681471665 612883.1326410668 560266.9986178024 496923.4174936912 449360.5439657976 596303.1674249779 493224.3867023026 496658.01145698235 474060.78235553636 1.2602682303920751 1.3809880346866048 1.2928366054575178 1.1818463358937232 1.0482272231517524 0.9478964738086811 1.2578622607464756 1.0404243613056225 1.047667366596249 1.0 18.854712522549782 -5.936106290067176 2.5058857473708605 1.064327920906264 1.3227349978920104 0.6692696685684599 0.08021885930465669 0.17185764419100474 2.1867517799788687 0.024737088528489708 0.039424671234185346 1.158493789456991e-06 5.936106290067176 0.2584070769857465 FS(ph)PVTPK ddPTM_PC-9_Lapatinib_30min_R1 4 FSPVTPK 7 0 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 FS(0.999)PVT(0.001)PK;FS(0.998)PVT(0.002)PK;FS(1)PVTPK;FS(0.997)PVT(0.003)PK 101.46 0.011192 373630000.0 2109620.0 2991870.0 2779560.0 2893000.0 3522540.0 3195090.0 3330440.0 3238750.0 3274120.0 2660210.0 True False 2079536.4319430776 2984942.508834941 2551035.306211885 3105760.870765095 3315351.1227801004 3058443.4488185695 3502873.8872319274 3389234.148638172 2905354.127587924 3120023.753992982 0.6665130126915549 0.9567050587402851 0.8176332962039439 0.9954285978721689 1.0626044492568814 0.9802628729683219 1.1227074418100107 1.0862847259738508 0.9311961563977434 1.0 21.573125582269846 -3.9624355914332927 0.605602378731652 1.0414877294980989 2.1921419139222186e-16 0.6483559210431884 0.07580635176697409 5.4376476638207905 0.7238484648075999 0.03504382793221514 4.932460262503724 0.00010903461855003049 3.9624355914332927 -1.0414877294980986 FS(ph)SPIVK ddPTM_PC-9_Lapatinib_30min_R1 2 FSSPIVK 7 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 FS(0.586)S(0.414)PIVK;FS(0.5)S(0.5)PIVK 101.25 0.011258 55225000.0 441700.0 388530.0 463960.0 375650.0 374220.0 355400.0 359210.0 293220.0 372210.0 273710.0 True False 435401.27700213954 387630.3826562114 425814.999737392 403276.5541316645 352209.1153448278 340200.37047786446 377808.1361719716 306844.0716522374 330287.79025493877 321020.40880435007 1.3563040388111285 1.2074945144452096 1.3264421452933552 1.2562333828982397 1.0971549025703413 1.059746860783558 1.1768975610589032 0.9558397635685754 1.0288685117719005 1.0 18.29230549373102 -6.452054062731766 0.6856376353649093 1.0052194399223238 1.3245400622739356 0.7669266485827181 0.06380957798714462 0.380107833763582 0.3953334840580809 0.04367223571044901 0.06367695017370037 3.531392068604311e-07 6.452054062731766 0.31932062235161185 FS(ph)SPTEELDYR ddPTM_PC-9_AZD4547_30min_R2 2 FSSPTEELDYR 11 0 D6RAA5;Q4VXL8;E7EMZ9;E9PBC6;O95359-6;O95359-1;O95359-5;O95359-3;O95359;H0Y911;Q4VXL4;E9PGB3;O95359-2 D6RAA5 TACC2 Transforming acidic coiled-coil-containing protein 2 1 FS(0.983)S(0.017)PTEELDYR;FS(0.938)S(0.062)PT(0.001)EELDYR 130.44 0.00020925 5880200.0 25826.8 23931.8 23430.0 29176.0 28581.0 25288.0 23224.0 30855.0 23974.0 26204.0 True False 34039.18516918799 31667.286338143873 23119.30289110995 22449.92396470655 24613.021493971162 23706.737362397656 25290.89100915056 26087.068727364003 25241.216696108975 25286.605935876843 1.346134995558772 1.2523343946770678 0.9142904725820912 0.8878187931443348 0.9733620066048487 0.9375215251313085 1.0001694601989917 1.03165560429569 0.9982050086166974 1.0 14.626085785546872 -5.162919082835481 4.288420599907119 0.966588771786829 1.323306796511954 0.903020791117389 0.04375014033375655 0.06669927960232287 2.0891622793106306 0.01269463932434715 0.03748897495244612 6.871964656095054e-06 5.162919082835481 0.35671802472512504 FSAS(ph)SGGGGSR ddPTM_PC-9_AZD4547_30min_R2 4 FSASSGGGGSR 11 0 H0Y3P2;D3DQV9;P78344-2;P78344;H0YCH5;H0YD99;H0YEN8;H0YDC0;H0YCF8;H0YEC5;H0YD77 H0Y3P2 EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 1 FS(0.001)AS(0.499)S(0.499)GGGGSR;FSAS(0.5)S(0.5)GGGGSR;FS(0.129)AS(0.435)S(0.435)GGGGSR;FS(0.015)AS(0.493)S(0.493)GGGGSR 145.14 0.00019553 106474000.0 332335.0 285057.0 388636.0 623404.0 506116.0 436497.0 353523.0 493258.0 395230.0 504279.0 True False 438010.6170025751 377196.100656544 383482.43270974816 479687.8392957886 435850.5295980799 409202.7735872549 384985.86213520204 417036.3100412285 416121.05092196295 486624.3457005821 0.9001000892628607 0.7751278866113928 0.7880461306506503 0.9857456650780446 0.8956611674876146 0.8409007424364165 0.7911356378623979 0.8569984500895259 0.8551176171074689 1.0 18.8924489742094 -12.030671793982531 1.5458875568313832 1.8963566076799268 0.8529442030856378 0.34685146663905164 0.05994854460833889 769961.2726252014 54063.386883521074 2400028.2698610704 0.017936427224862897 9.31811800389808e-13 12.030671793982531 -1.043412404594289 FSAS(ph)SGGGGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FSASSGGGGSR 11 0 H0Y3P2;D3DQV9;P78344-2;P78344;H0YCH5;H0YD99;H0YEN8;H0YDC0;H0YCF8;H0YEC5;H0YD77 H0Y3P2 EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 1 FS(0.015)AS(0.493)S(0.493)GGGGSR;FS(0.217)AS(0.392)S(0.392)GGGGSR 117.86 0.0011206 36597700.0 127313.0 120396.0 152570.0 155807.0 180270.0 175719.0 146820.0 195421.0 164542.0 127454.0 True False 148864.57635363078 132348.11921055533 156207.84742494696 147077.63892310936 144947.3875790229 166503.98630437968 132912.14671525016 190291.40581566477 166948.11546711918 150560.40127469084 0.9887365807562767 0.8790367061329227 1.0375095051716328 0.9768680056502551 0.962719190118076 1.1058949424596742 0.882782893708936 1.2638874777471298 1.1088447829155932 1.0 17.199982852702476 -7.755411083380092 24.99999958453806 1.1397745996063624 0.9793335383991103 0.3759875747236989 0.08663251310161009 130.6326885564887 541754.3585713926 0.03977611928961169 0.02219352050287796 1.756260430787234e-08 7.755411083380092 -0.1604410612072521 FSAS(ph)SGGGGSR ddPTM_PC-9_Lapatinib_30min_R1 2 FSASSGGGGSR 11 0 H0Y3P2;D3DQV9;P78344-2;P78344;H0YCH5;H0YD99;H0YEN8;H0YDC0;H0YCF8;H0YEC5;H0YD77 H0Y3P2 EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 1 FS(0.001)AS(0.498)S(0.498)GGGGS(0.003)R;FS(0.005)AS(0.497)S(0.497)GGGGSR 82.494 0.013881999999999999 50765000.0 127244.0 138624.0 164108.0 146450.0 138119.0 153108.0 129368.0 131013.0 142341.0 101293.0 True False 125429.47722630852 138303.02464503344 150615.67371519952 157220.4215428783 129995.11197240179 146559.92775218008 136066.04203751445 137100.342266471 126309.05766281998 118801.36008556151 1.0557915930926498 1.1641535462677086 1.2677941869245026 1.32338907087972 1.094222422022597 1.233655301981616 1.1453239419104193 1.1540300731214732 1.0631953840583255 1.0 16.8581918272208 -8.324914212267139 1.1478643769830987 0.9987097121942543 1.193815206436665 0.40831254488796254 0.07425868310507099 0.47229470458509115 1.2925943209153343 0.07259709668046581 0.023619982196277676 4.7324473144331595e-09 8.324914212267139 0.19510549424241064 FSASGELGNGNIK ddPTM_PC-9_Lapatinib_30min_R1 1 FSASGELGNGNIK 13 0 P12004 P12004 PCNA Proliferating cell nuclear antigen 0 184.44 0.00023833 7833400.0 14583.0 22139.0 18981.0 20457.0 18203.0 14461.0 18059.0 12384.0 17366.0 15034.0 False True 14375.043745805326 22087.73850571612 17420.455448778852 21961.47602255149 17132.33532847495 13842.536740237463 18994.006656634374 12959.405850014697 15410.058207912922 17632.606868454204 0.8152534592898538 1.2526643774513238 0.987968232873444 1.2455036391608034 0.9716280443549008 0.7850533300894149 1.0772092180320652 0.7349682294113784 0.8739523499206714 1.0 14.105958163235547 -6.517508007495233 24.60361980446119 0.8879115474301297 1.0851208471555585 0.24856460059338936 0.14785948461482543 242.77825489838614 1112187.367508653 0.045054583337806015 0.046378914225630445 3.037330089322436e-07 6.517508007495233 0.19720929972542878 FSASS(ph)GGGGSR ddPTM_PC-9_Lapatinib_30min_R1 1 FSASSGGGGSR 11 0 H0Y3P2;D3DQV9;P78344-2;P78344;H0YCH5;H0YD99;H0YEN8;H0YDC0;H0YCF8;H0YEC5;H0YD77 H0Y3P2 EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 1 FS(0.005)AS(0.152)S(0.842)GGGGSR 111.5 0.0018047999999999999 31321000.0 137220.0 102950.0 129900.0 110690.0 116610.0 122930.0 122430.0 80060.0 139130.0 83158.0 True False 135263.21763693375 102711.62560022918 119220.1234285007 118830.51185101522 109751.22906408095 117672.57046382639 128768.8263454092 83779.87987339939 123459.71429614918 97531.74949893016 1.3868634401807534 1.053109639967607 1.222372448366759 1.2183777330100973 1.125287197532377 1.206505277187888 1.320275981995193 0.859001097630453 1.2658412766142724 1.0 16.57358431521606 -14.52287826878355 0.05855763643899079 0.30232275932971575 1.4740047464645103 0.18384066057787352 0.13590847932596195 736.9477253753591 3.1464542573108814 73.5804745934162 12.734687774346712 3.000003291525002e-15 14.52287826878355 1.1716819871347945 FSAVALCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FSAVALCK 8 0 P09936;D6RE83 P09936 UCHL1 Ubiquitin carboxyl-terminal hydrolase isozyme L1;Ubiquitin carboxyl-terminal hydrolase 0 109.86 0.017376 4239600.0 46360.0 44332.0 40834.0 50672.0 44558.0 43960.0 45249.0 42800.0 42709.0 36908.0 False True 54207.832348262324 48732.987980018814 41807.637423807384 47833.01212084054 35827.179762279375 41654.660212842835 40962.68714560933 41676.545350348504 43333.53832751016 43599.12823643275 1.2433237668033146 1.1177514310778365 0.9589099395999312 1.0971093702022654 0.8217407368329237 0.9554012178168952 0.9395299585687511 0.9559031805485121 0.9939083665278277 1.0 15.41201166818585 -4.661164408030322 1.0124836067277951 0.9514671597688387 1.459029866737296 0.6651170654116506 0.06415266877352838 1.3306176314296727 0.9370767373514892 0.020408680239748907 0.7787867531117788 2.1819037663962517e-05 4.661164408030322 0.5075627069684574 FSAVALCK ddPTM_PC-9_Lapatinib_30min_R1 2 FSAVALCK 8 0 P09936;D6RE83 P09936 UCHL1 Ubiquitin carboxyl-terminal hydrolase isozyme L1;Ubiquitin carboxyl-terminal hydrolase 0 ; 124.08 0.015285 19565900.0 151009.0 167935.0 176131.0 141574.0 150322.0 155175.0 159813.0 132513.0 133394.0 168281.0 False True 148855.58396834126 167546.15682539577 161650.18906532147 151985.82423701958 141480.35550442294 148538.52698059252 168087.3351689854 138670.03774249027 118369.76301890681 197368.14662966234 0.7542026740903177 0.8489017082365172 0.8190287633831748 0.7700625801700552 0.7168347979164736 0.7525962497854695 0.851643682323172 0.7025958347913555 0.5997409665147917 1.0 17.590529645550518 -5.853536260200066 5.080470289688881 0.757689878911024 0.8113464588710937 0.017123003970271666 0.10099113773688366 0.6904347121062232 29.35864640801847 0.027865790300104498 0.04246387626810038 1.401082600593136e-06 5.853536260200066 0.05365657996006967 FSCPPNFTAKPPASES(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 FSCPPNFTAKPPASESPR 18 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 FS(0.001)CPPNFT(0.016)AKPPAS(0.408)ES(0.574)PR;FSCPPNFTAKPPAS(0.013)ES(0.987)PR 124.45 2.1189e-05 39797000.0 47690.0 52464.0 57961.0 86097.0 77491.0 68867.0 60265.0 70290.0 66386.0 79230.0 True False 62854.42798637759 69421.96201056246 57192.39926895535 66248.66683538994 66732.71224202507 64560.735603299625 65628.46825122547 59428.29560351373 69895.02843029481 76456.18181573493 0.8220973960988717 0.9079967160520066 0.748041530595829 0.8664919599968273 0.8728229772558594 0.8444148539734273 0.8583801426207097 0.7772856843249161 0.9141841348911068 1.0 16.222345534037373 -8.532515829222804 6.354943671978277 0.9999779540109808 0.8398735965759615 0.5775150439994892 0.044127914599135974 0.08693494008841308 23.92858009084467 0.04068664069866916 0.010537609361503568 2.9341625572614225e-09 8.532515829222804 -0.16010435743501927 FSCPPNFTAKPPASES(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FSCPPNFTAKPPASESPR 18 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 FSCPPNFTAKPPAS(0.341)ES(0.659)PR;FSCPPNFT(0.003)AKPPAS(0.142)ES(0.855)PR 105.22 0.00016393 27399000.0 48931.0 44291.0 49955.0 54970.0 51901.0 52773.0 50403.0 56778.0 48586.0 40042.0 True False 57214.051868697694 48687.91777097838 51146.116655392514 51890.209115144535 41731.37162444593 50005.49097844305 45628.46295388067 55287.63766126373 49296.478334318504 47301.297627702384 1.2095662220308694 1.0293146322155846 1.0812835846058984 1.0970144946880827 0.8822458096795555 1.0571695383924717 0.9646344866268107 1.168839766224174 1.042180253115247 1.0 15.5295921414518 -2.6473590267329614 1.543250966445361 1.0354070662948178 137.40753410577082 0.323524428929697 0.07408656639627113 1269.4533548544418 4.984672069883641 0.020685635399854185 611587.2752459429 0.002252376426111399 2.6473590267329614 136.372127039476 FSCPPNFTAKPPASES(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 FSCPPNFTAKPPASESPR 18 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 FSCPPNFTAKPPAS(0.081)ES(0.918)PR;FSCPPNFTAKPPAS(0.172)ES(0.827)PR 98.376 0.00033726 27366000.0 51708.0 36915.0 45187.0 39246.0 45408.0 47933.0 36230.0 38856.0 45707.0 31078.0 True False 50970.63443791417 36829.52558555084 41471.899286864194 42132.281760818085 42737.190715562865 45883.01732728047 38105.81212524852 40661.391610801955 40558.99634395232 36449.79089116802 1.398379337486532 1.0104180212039249 1.1377815420310973 1.1558991349666965 1.1724948119227294 1.258800563884666 1.0454329419618635 1.115545264229607 1.1127360501203858 1.0 15.15362291752717 -14.522878656005625 0.06720821075731678 0.45526749520202076 1.3532988042468952 0.2652001455413292 0.09730584873919954 518.2359079673339 2.5088956422326754 44.06809941902822 5.922967806180111 3.000000616687928e-15 14.522878656005625 0.8980313090448744 FSDQAGPAIPTSNS(ph)YSK ddPTM_PC-9_Lapatinib_30min_R1 1 FSDQAGPAIPTSNSYSK 17 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4 E9PC69 MARK2 Serine/threonine-protein kinase MARK2 1 FSDQAGPAIPT(0.358)S(0.261)NS(0.378)Y(0.001)S(0.002)K 93.92 0.0017992000000000001 6726100.0 29051.0 29149.0 36448.0 35380.0 32148.0 24845.0 26529.0 24065.0 32296.0 22574.0 True False 28636.727412699074 29081.507281409224 33451.386133348664 37981.963224220155 30257.1178453998 23782.43726652374 27902.541812606083 25183.147753601723 28658.484388043045 26475.88582203572 1.0816154596370444 1.098414892588971 1.263466172886547 1.4345870608267994 1.1428179607957434 0.8982678587747103 1.053885108893428 0.9511730003247687 1.0824372253558656 1.0 14.69239133382103 -6.555362205280135 8.319032263945282 0.9996186582045754 1.2232636997637907 0.5170963318767707 0.10215913962699373 0.20615367637791565 46.38027213876249 0.03603000296876799 0.03621473907325026 2.783798488654637e-07 6.555362205280135 0.22364504155921527 FSDSTSKT(ph)PPQEELPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FSDSTSKTPPQEELPTR 17 1 F6Q6H0;I6L8A6;Q99708-3;Q99708;Q99708-2 F6Q6H0 RBBP8 DNA endonuclease RBBP8 1 FS(0.021)DS(0.024)T(0.267)S(0.267)KT(0.421)PPQEELPTR 60.631 0.025136000000000002 8917200.0 20407.0 18196.0 21782.0 27847.0 25537.0 25659.0 23371.0 25379.0 24009.0 17431.0 True False 23861.502043377677 20002.378626825375 22301.365488695013 26286.8228711921 20533.20816888837 24313.39686991205 21157.129688612677 24712.82814127323 24360.08620443446 20591.102316279925 1.1588258693907842 0.9714088308429663 1.0830583591954135 1.2766107645635354 0.9971883900870241 1.1807719905645444 1.0274889301038164 1.200170236720865 1.1830394424865087 1.0 14.32973344427738 -5.531953981084482 24.994028889761594 1.1292729887223318 1.0556463718674771 0.05593747057986087 0.09723046442896771 440.29197656306326 1212599.3818738624 0.024922636972293324 0.043252723743121765 2.9379609490639355e-06 5.531953981084482 -0.07362661685485472 FSDSTSKT(ph)PPQEELPTR ddPTM_PC-9_Lapatinib_30min_R1 2 FSDSTSKTPPQEELPTR 17 1 F6Q6H0;I6L8A6;Q99708-3;Q99708;Q99708-2 F6Q6H0 RBBP8 DNA endonuclease RBBP8 1 FS(0.022)DS(0.085)T(0.085)S(0.123)KT(0.685)PPQEELPTR;FS(0.002)DS(0.007)T(0.131)S(0.131)KT(0.729)PPQEELPTR 80.102 0.004297 19939700.0 105096.0 91643.0 130703.0 88736.0 106909.0 97294.0 86186.0 70626.0 121751.0 78229.0 True False 103597.3117677539 91430.80626402926 119957.10386817016 95261.94145461825 100620.82281118107 93132.96242339152 90648.28936866327 73907.54179288914 108038.12028513207 91750.77841640958 1.1291164342778544 0.9965125946841766 1.307423282271749 1.0382684822822246 1.096675412981402 1.015064548016246 0.9879838725428282 0.8055249565018493 1.1775172063914556 1.0 16.485432777426063 -6.736930644532988 1.8048142999419923 0.9776421372291412 1.1220187849948482 0.21074367181007458 0.1127275195651702 0.5047810558177989 3.39686135339776 0.04503733280932912 0.04192502904467097 1.8326070606052506e-07 6.736930644532988 0.14437664776570702 FSEGVLQS(ph)PSQDQEK ddPTM_PC-9_AZD4547_30min_R2 4 FSEGVLQSPSQDQEK 15 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 FSEGVLQS(0.972)PS(0.028)QDQEK;FSEGVLQS(0.969)PS(0.031)QDQEK;FS(0.001)EGVLQS(0.94)PS(0.059)QDQEK;FSEGVLQS(0.939)PS(0.061)QDQEK 214.54 4.223399999999999e-64 53929100.0 417086.0 381325.0 503527.0 595696.0 634980.0 642484.0 477321.0 505012.0 458350.0 584556.0 True False 549710.6720722634 504580.8490331992 496849.90298130334 458367.49061145564 546823.9875526332 602309.3739142168 519801.6443066971 426973.9994212792 482577.44525992917 564090.8723649989 0.9745072983853732 0.8945027720758911 0.8807976291093276 0.8125773932304754 0.9693898879448751 1.0677523842727388 0.9214856502240225 0.7569241417276518 0.8554959296481474 1.0 19.10556806711387 -10.552449777893262 4.699714513811276 1.0000026656605767 0.9030508564229658 0.1073590142536025 0.08327156556985746 2.5463284556050704e-06 5.256128546065497e-07 0.0882693273632561 0.021407867928213455 2.8025296893517436e-11 10.552449777893262 -0.09695180923761093 FSEGVLQS(ph)PSQDQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 FSEGVLQSPSQDQEK 15 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 FSEGVLQS(0.988)PS(0.012)QDQEK;FS(0.001)EGVLQS(0.979)PS(0.02)QDQEK;FSEGVLQS(0.931)PS(0.069)QDQEK;FSEGVLQS(0.955)PS(0.045)QDQEK;FSEGVLQS(0.892)PS(0.108)QDQEK;FSEGVLQS(0.988)PS(0.012)QDQEK 176.33 5.42e-05 64148100.0 140227.0 144637.0 145369.0 182148.0 213029.0 209354.0 237290.0 179121.0 189929.0 172824.0 True False 163964.66149050478 158995.6054873674 148835.14827500255 171942.8380917835 171287.49669147178 198375.10769334616 214812.17336917148 174419.26354438715 192706.35231463335 204155.6231259688 0.8031356618050866 0.7787961117743174 0.7290279150585423 0.8422145589675516 0.8390045499054581 0.9716857398091067 1.0521981715714357 0.8543446458820603 0.9439189054113343 1.0 17.63930977917463 -6.510669567196556 2.05501658969725 0.9607152593092618 0.7796124473156286 0.705745733895665 0.05403679820682094 0.19034649890039926 1.6138330547349562 0.020537546629146867 0.022385223336786355 3.0855346853573905e-07 6.510669567196556 -0.1811028119936332 FSEGVLQS(ph)PSQDQEK ddPTM_PC-9_Lapatinib_30min_R1 4 FSEGVLQSPSQDQEK 15 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 FSEGVLQS(0.959)PS(0.041)QDQEK;FSEGVLQS(0.911)PS(0.088)QDQEK;FS(0.001)EGVLQS(0.858)PS(0.142)QDQEK;FSEGVLQS(0.999)PS(0.001)QDQEK 201.04 3.1156e-10 82898600.0 380614.0 332814.0 321420.0 298714.0 444681.0 384843.0 381600.0 389094.0 386420.0 320202.0 True False 375186.3745639406 332043.38963103073 294994.08831708034 320682.424040693 418525.7378564839 368384.1620028496 401357.38081685995 407172.72769748216 342897.31041700544 375548.48905765347 0.9990357716666056 0.8841558395407526 0.7855019975111481 0.8539041785133169 1.114438614589214 0.9809230305445218 1.0687231942377602 1.0842081370615602 0.9130573558621468 1.0 18.518639668212828 -6.246492238076232 24.895782208041062 1.0308952686897164 0.8741036452303429 0.4927772295983722 0.07249660804030139 631.0000910049739 1050986.0150065606 0.021595453824834212 0.02776222010489071 5.669017033776508e-07 6.246492238076232 -0.15679162345937347 FSEQDS(ph)PPPSHPLK ddPTM_PC-9_Lapatinib_30min_R1 1 FSEQDSPPPSHPLK 14 0 Q9Y2K6 Q9Y2K6 USP20 Ubiquitin carboxyl-terminal hydrolase 20 1 FS(0.367)EQDS(0.633)PPPSHPLK 73.168 0.035311 0.0 21989.0 19420.0 18797.0 15691.0 16914.0 19142.0 14823.0 15931.0 19188.0 14059.0 True False 21675.432827711276 19375.03418316125 17251.58321851829 16844.96848364155 15919.151774203436 18323.341282181424 15590.46241050397 16671.21241897483 17026.84538140235 16489.07941756005 1.3145326236119659 1.1750221884751069 1.0462429576357195 1.0215833193029864 0.9654360544379652 1.1112410109850024 0.9455022937120978 1.0110456743401222 1.0326134619298155 1.0 14.009223235159608 -4.930545272635966 1.5090780743908363 1.011252487622697 1.384060033666474 0.8455287921066011 0.04141786794511132 0.2920199841095903 0.7750934721970598 0.011572292336211213 0.15064010436749636 1.1734233536578278e-05 4.930545272635966 0.37280754604377697 FSFSPEPTLEDIRR ddPTM_PC-9_AZD4547_30min_R2 1 FSFSPEPTLEDIRR 14 1 Q9H773 Q9H773 DCTPP1 dCTP pyrophosphatase 1 0 156.52 0.00022773 5360100.0 13589.0 10149.0 17380.0 23920.0 20876.0 15382.0 13274.0 16687.0 15516.0 17003.0 False True 17910.019331241016 13429.465775487937 17149.52984410973 18405.613560316015 17977.72774599006 14420.161108367638 14455.360284854658 14108.40757911272 16336.144083458199 16407.730145310423 1.0915598423807555 0.818484071626829 1.0452103790243847 1.1217647655898715 1.0956864591735358 0.8788638635971922 0.8810091436679447 0.8598634579046338 0.9956370527051431 1.0 14.002088048955235 -6.7721934741656336 24.999145505897246 0.9116870614196563 1.0279764359250763 0.27118241607634397 0.0900881738729761 301.38178606272675 700592.8862724359 0.03308045746720891 0.02945811209473689 1.689688023598396e-07 6.7721934741656336 0.11628937450541998 FSFSPEPTLEDIRR ddPTM_PC-9_Lapatinib_30min_R1 1 FSFSPEPTLEDIRR 14 1 Q9H773 Q9H773 DCTPP1 dCTP pyrophosphatase 1 0 66.708 0.022782 2160100.0 11876.0 14320.0 13168.0 11784.0 10776.0 12279.0 10964.0 10813.0 10923.0 11749.0 False True 11706.646062208336 14286.842919818171 12085.377869949942 12650.634670271622 10142.176866431135 11753.855793747041 11531.66227273598 11315.41145479724 9692.73671571075 13779.798995441566 0.8495512936060213 1.03679617711001 0.877035860533804 0.9180565459958104 0.7360177655556677 0.8529773037789072 0.8368527201703536 0.821159398518109 0.7034018942451309 1.0 13.75026722329596 -6.127056667289384 8.232753121412184 0.8181957537839426 0.9268847581924055 0.22181079283017335 0.08666366234139822 0.3911265119463665 24.320490532634903 0.024186637067404527 0.0312975442276303 7.463513671926837e-07 6.127056667289384 0.10868900440846285 FSGDLDDQTCR ddPTM_PC-9_AZD4547_30min_R2 2 FSGDLDDQTCR 11 0 P05455 P05455 SSB Lupus La protein 0 ; 194.12 0.00069481 13502100.0 43416.0 48867.0 65718.0 69818.0 60273.0 67790.0 52512.0 66606.0 55500.0 51142.0 False True 57221.384891100155 64662.30210373129 64846.53638062155 53722.53877734713 51905.13433771116 63551.080583554976 57185.46627077659 56313.57315361549 58433.61669450433 49351.534146413316 1.159465169235449 1.3102389464103559 1.3139720477227423 1.088568769067364 1.0517430761872968 1.2877224929829993 1.1587373576092288 1.1410703664560375 1.1840283732851506 1.0 15.590807312681388 -14.522878742445137 0.11000890859892203 0.4039346091920562 1.2956644717316252 0.33409165443644895 0.08363385640252077 210.2250496137517 1.5317759930949983 28.339827745026504 1.1205296259951119 3.0000000195848724e-15 14.522878742445137 0.8917298625395691 FSGDLDDQTCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FSGDLDDQTCR 11 0 P05455 P05455 SSB Lupus La protein 0 ; 123.51 0.0025949000000000002 9237000.0 32179.0 32889.0 39572.0 33469.0 37286.0 27367.0 36294.0 27324.0 30109.0 22931.0 False True 37626.26913577942 36154.0025641712 40515.546557645735 31593.840437962015 29980.075959790574 25931.826343149896 32855.96957419491 26606.773952171086 30549.28716436827 27088.208778303862 1.3890275818427666 1.3346767540099782 1.4956893934639346 1.166331841892289 1.1067574163044305 0.9573104872079927 1.2129251455161074 0.982227144287282 1.1277706626669437 1.0 14.725377377294006 -5.9252737956183426 4.255444600981703 1.0701359959115126 1.3979633118908152 0.7804417184583404 0.08084310855368902 0.09416194163477376 3.29659984313361 0.022325326577044228 0.03381393167729871 1.187753186951721e-06 5.9252737956183426 0.3278273159793026 FSGEEGEIEDDES(ph)GTENR ddPTM_PC-9_Lapatinib_30min_R1 2 FSGEEGEIEDDESGTENR 18 0 Q9Y2W1 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 FSGEEGEIEDDES(0.99)GT(0.01)ENR;FSGEEGEIEDDES(0.711)GT(0.289)ENR 242.9 2.7729e-53 25800000.0 73117.0 94528.0 70432.0 77787.0 94117.0 92015.0 98272.0 101904.0 93747.0 85162.0 True False 72074.33817198436 94309.12622378301 64641.352835382335 83507.71546982527 88581.22310114144 88079.73294744139 103360.04331141095 106638.83185884202 83188.22566032554 99882.13822876802 0.7215938650302696 0.9442041179352739 0.6471763018061257 0.8360625528316274 0.8868574969656418 0.8818366778022448 1.0348200904017213 1.0676466658593011 0.8328638847297494 1.0 16.607939085667603 -6.675606276001796 1.498560202030637 0.9849896879197261 0.7882732394522248 0.4524071533761421 0.09387247345016878 0.36040021463689126 1.6814512725125934 0.03976872296962452 0.03872439104767376 2.1105406631813756e-07 6.675606276001796 -0.19671644846750125 FSGEEGEIEDDES(ph)GTENREEK ddPTM_PC-9_AZD4547_30min_R2 2 FSGEEGEIEDDESGTENREEK 21 1 Q9Y2W1 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 FSGEEGEIEDDES(0.819)GT(0.18)ENREEK;FSGEEGEIEDDES(0.983)GT(0.017)ENREEK 61.903999999999996 0.0037235 18543400.0 36202.0 51908.0 33567.0 30913.0 27826.0 38801.0 49260.0 58294.0 47111.0 39094.0 True False 47713.48295162172 68686.24588373507 33121.8796477118 23786.48545108901 23962.840211722523 36374.767336222394 53644.044570735314 49286.001762857086 49601.191280987325 37725.33095928752 1.2647598241911575 1.8206929969112795 0.8779745281348577 0.6305176083613142 0.6351923124964172 0.9642000854936797 1.4219635244188307 1.306443191076193 1.314798042050738 1.0 15.203245936927742 -5.271031025224126 24.826789658988325 1.0146994410518635 1.5427264223037798 0.3518165393027879 0.2843677026098734 664.2724001162269 1719390.0375421129 0.08461448036484992 0.1798900443811256 5.3575838252177335e-06 5.271031025224126 0.5280269812519163 FSGEEGEIEDDES(ph)GTENREEK ddPTM_PC-9_Lapatinib_30min_R1 2 FSGEEGEIEDDESGTENREEK 21 1 Q9Y2W1 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 FSGEEGEIEDDES(0.936)GT(0.064)ENREEK;FSGEEGEIEDDES(0.996)GT(0.004)ENREEK 94.72 0.00017448 26751000.0 23898.0 45563.0 30775.0 34764.0 46887.0 39717.0 44656.0 47869.0 37221.0 41906.0 True False 23557.210137643528 45457.5016728824 28244.79829493542 37320.66052930438 44129.19884338873 38018.396494849025 46968.069176513876 50093.168494376085 33028.77902549389 49149.396263764924 0.47929805711593104 0.9248842331435849 0.5746723345970928 0.7593310064078813 0.8978584112521988 0.7735272329861321 0.9556184357678628 1.0192021123829542 0.6720078278935878 1.0 15.584886074597057 -6.107595521505511 3.7749231497341884 0.8849483803660572 0.6832905499764615 0.33197964022324633 0.14378418706062154 0.2998359866941576 7.660537503254999 0.041495974081586555 0.0557863515072008 7.805567406153361e-07 6.107595521505511 -0.20165783038959562 FSGEEGEIEDDES(ph)GTENREEKDNIQPTTE ddPTM_PC-9_AZD4547_30min_R2 2 FSGEEGEIEDDESGTENREEKDNIQPTTE 29 2 Q9Y2W1 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 FS(0.003)GEEGEIEDDES(0.807)GT(0.189)ENREEKDNIQPT(0.002)TE;FSGEEGEIEDDES(0.825)GT(0.174)ENREEKDNIQPTTE 70.449 0.00025869 61887100.0 44977.0 47036.0 49372.0 55577.0 56574.0 61846.0 48915.0 49593.0 49086.0 50483.0 True False 59278.75042028316 62239.46716088782 48717.2950209083 42764.581306090455 48719.676638323515 57978.759843200205 53268.340239088895 41929.541383768 51680.5857489449 48715.605535829294 1.216832876616609 1.2776084065117903 1.000034680572281 0.8778415219459401 1.0000835687548053 1.1901475760279334 1.0934553651377927 0.8607004043689802 1.0608630474876253 1.0 15.572096378195857 -5.264517860764598 24.678203533430178 1.0097002406707543 1.2472206565938055 0.5167850065316892 0.09160147611573917 171.88985617468185 1377944.1076008517 0.025661638298735703 0.05732765624148521 5.438537647684501e-06 5.264517860764598 0.2375204159230513 FSGEEGEIEDDES(ph)GTENREEKDNIQPTTE ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 FSGEEGEIEDDESGTENREEKDNIQPTTE 29 2 Q9Y2W1 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 FSGEEGEIEDDES(0.831)GT(0.169)ENREEKDNIQPTTE;FSGEEGEIEDDES(0.499)GT(0.499)ENREEKDNIQPT(0.001)TE;FSGEEGEIEDDES(0.817)GT(0.182)ENREEKDNIQPT(0.001)TE;FS(0.001)GEEGEIEDDES(0.499)GT(0.499)ENREEKDNIQPTTE 72.935 9.0482e-05 95283000.0 137414.0 145090.0 136250.0 156549.0 187089.0 144159.0 173015.0 128260.0 140093.0 120421.0 True False 160675.47614978714 159493.5763335952 139498.7167310026 147778.06706870586 150430.25347962396 136599.04826258446 156625.76667987384 124893.31090270332 142141.59509508277 142252.3740478887 1.129509979887551 1.1212015082426836 0.9806424508883129 1.0388442938671587 1.0574885268978513 0.960258478474313 1.1010414956389156 0.8779699582423733 0.9992212505868715 1.0 17.11809320428702 -1.5228787452803778 0.3792417302214977 0.980919539581964 3.2916776770233622 0.38759231626368174 0.05869069406988466 67.95291745536264 0.9285398512905126 0.044118643573720105 115.31955520401911 0.02999999999999722 1.5228787452803778 2.310758137441398 FSGEEGEIEDDES(ph)GTENREEKDNIQPTTE ddPTM_PC-9_Lapatinib_30min_R1 3 FSGEEGEIEDDESGTENREEKDNIQPTTE 29 2 Q9Y2W1 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 FSGEEGEIEDDES(0.809)GT(0.189)ENREEKDNIQPT(0.002)TE;FSGEEGEIEDDES(0.868)GT(0.131)ENREEKDNIQPTTE;FSGEEGEIEDDES(0.797)GT(0.203)ENREEKDNIQPTTE 81.105 5.1751e-06 135860000.0 78565.0 100047.0 99154.0 93216.0 101130.0 98275.0 89709.0 98163.0 95835.0 93269.5 True False 77444.64869294345 99815.34731836927 91001.94086550853 100071.41559946036 95181.73222922982 94072.00734021419 94353.69307049192 102724.01134165001 85041.05311271072 109391.00880120306 0.7079617378214701 0.9124639073377987 0.8318959836167789 0.914804760428901 0.8701056263426928 0.8599610550367244 0.8625360905297204 0.9390535151598334 0.777404414171336 1.0 16.739134637695358 -14.522878745280336 0.18662042292895717 1.5580425803437847 0.8346065236739486 0.30330470036340607 0.0656493193307269 173.48127020915774 1.6836115104155427 36.35009572766986 0.17600915385357152 3.0000000000000132e-15 14.522878745280336 -0.7234360566698361 FSGEEGEIEDDESGT(ph)ENREEK ddPTM_PC-9_Lapatinib_30min_R1 1 FSGEEGEIEDDESGTENREEK 21 1 Q9Y2W1 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 FSGEEGEIEDDES(0.231)GT(0.769)ENREEK 57.17100000000001 0.010621 6693600.0 5097.5 10268.0 8721.6 9482.3 10419.0 7515.1 9430.5 11796.0 7417.4 9200.5 True False 5024.808715232991 10244.225076864035 8004.543714349594 10179.659974025515 9806.174904542138 7193.696691553742 9918.765146209118 12344.085223415163 6581.974303315284 10790.794166104362 0.46565698852979065 0.949348576126381 0.7417937541143326 0.9433652257033575 0.9087537722983288 0.6666512752277597 0.9191876884618531 1.143945944422695 0.6099619918606486 1.0 13.397513425778353 -4.754964440943146 24.980501929063628 0.8741475796658332 0.4656562973457735 0.3942546365118087 0.15253484338795442 221.30340667688392 853715.2364010359 0.03625545811928367 0.33605031779195305 1.7580675546890072e-05 4.754964440943146 -0.4084912823200597 FSGFSAKPNNSGEAPS(ph)SPTPK ddPTM_PC-9_AZD4547_30min_R2 1 FSGFSAKPNNSGEAPSSPTPK 21 1 P49916-4;P49916-3;P49916-2;P49916;K7ENR9;K7ERZ5 P49916-4 LIG3 DNA ligase 3 1 FSGFSAKPNNSGEAPS(0.476)S(0.476)PT(0.047)PK 97.256 0.00013884 33289000.0 97650.0 89565.0 87285.0 96619.0 106770.0 117500.0 110600.0 106750.0 105030.0 94976.0 True False 128700.66875382222 118515.13471096427 86127.54386899408 74344.98229866955 91946.82848435307 110152.70642524998 120443.18573941007 90254.24037096459 110581.6713770054 91650.91914844434 1.4042485329074492 1.2931145242417998 0.9397346438991603 0.8111755232727687 1.0032286565007542 1.2018723592595817 1.3141514221404775 0.98476088630145 1.2065527809699264 1.0 16.483861728882566 -5.086575770485983 4.870954518265179 1.0615099108510893 1.3813963277069243 0.4170299265811761 0.14009774684727086 0.2135417980312869 8.45206593838101 0.03979816494951704 0.11772202620814153 8.192646752483122e-06 5.086575770485983 0.3198864168558351 FSGFSAKPNNSGEAPS(ph)SPTPK ddPTM_PC-9_Lapatinib_30min_R1 2 FSGFSAKPNNSGEAPSSPTPK 21 1 P49916-4;P49916-3;P49916-2;P49916;K7ENR9;K7ERZ5 P49916-4 LIG3 DNA ligase 3 1 FSGFSAKPNNSGEAPS(0.416)S(0.416)PT(0.168)PK;FSGFSAKPNNSGEAPS(0.46)S(0.428)PT(0.112)PK 73.688 0.0008068999999999999 40748000.0 135731.0 158876.0 153620.0 149600.0 154451.0 146064.0 158431.0 153787.0 160366.0 144634.0 True False 133795.45104998283 158508.1323833126 140989.95659034885 160602.08305097077 145366.49584234934 139817.18321181418 166633.78197116352 160932.50544704523 142303.8923511555 169633.79418730945 0.788731111574655 0.9344136476030719 0.8311430942508301 0.9467575952090898 0.8569430197489765 0.8242295344607348 0.982314772651767 0.9487054523424957 0.8388888135934971 1.0 17.37206408448946 -14.522878743765151 0.07904125313214463 1.3565179577222304 0.777616285766638 0.2811095970173263 0.06039638174837157 357.36754844689335 1.9959092316021916 22.49096912185273 2.1457433696992516 3.0000000104665365e-15 14.522878743765151 -0.5789016719555924 FSGFSAKPNNSGEAPSS(ph)PTPK ddPTM_PC-9_AZD4547_30min_R2 1 FSGFSAKPNNSGEAPSSPTPK 21 1 P49916-4;P49916-3;P49916-2;P49916;K7ENR9;K7ERZ5 P49916-4 LIG3 DNA ligase 3 1 FSGFSAKPNNSGEAPS(0.136)S(0.632)PT(0.232)PK 73.294 0.00086554 33295000.0 77947.0 59368.0 62304.0 74748.0 69487.0 82901.0 74105.0 61874.0 61749.0 66753.0 True False 102732.5246016809 78557.54499548407 61477.80825128959 57516.003445087874 59839.92948292827 77717.18736476322 80700.20143959261 52312.79502307308 65012.92607691804 64415.997788031884 1.5948293611741275 1.2195347071077987 0.95438726965915 0.8928838397310987 0.9289606858196674 1.2064889163170367 1.2527975069973416 0.8121087434710589 1.00926677082377 1.0 15.975131407380923 -4.8510171785128 2.5833169984782876 1.0104233220790821 1.6692593749298148 0.6666933211064932 0.1273582550295524 0.2680739473218816 2.6310114846782313 0.036117255382091304 0.3660344123706527 1.4092330551235497e-05 4.8510171785128 0.6588360528507327 FSGFSAKPNNSGEAPSS(ph)PTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FSGFSAKPNNSGEAPSSPTPK 21 1 P49916-4;P49916-3;P49916-2;P49916;K7ENR9;K7ERZ5 P49916-4 LIG3 DNA ligase 3 1 FSGFSAKPNNSGEAPS(0.474)S(0.498)PT(0.028)PK;FSGFSAKPNNSGEAPS(0.024)S(0.815)PT(0.161)PK 101.5 7.926399999999999e-05 54580000.0 168588.0 198243.0 179339.0 218780.0 206590.0 154312.0 200861.0 187300.0 171663.0 170184.0 True False 197126.61863522153 217923.2548976552 183615.12190694455 206522.46589433015 166110.1725187235 146219.60706924956 181833.99197229155 182383.5734607545 174173.24662051038 201037.01202419683 0.9805488882390242 1.083995691656151 0.9133398873081372 1.027285790884482 0.8262666204904123 0.7273268021494995 0.9044801757718425 0.907213908644856 0.8663740316611296 1.0 17.617101608418693 -6.259170969967011 24.968641992400592 0.8617002735443443 1.0009176006226572 0.4050956760271933 0.07618663858029492 194.6919748745196 2142993.508400841 0.023135449573552975 0.028429460751274373 5.505909010196892e-07 6.259170969967011 0.1392173270783129 FSGIS(ph)GCSDGVSQEGSASSTK ddPTM_PC-9_AZD4547_30min_R2 1 FSGISGCSDGVSQEGSASSTK 21 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 FS(0.125)GIS(0.437)GCS(0.437)DGVS(0.002)QEGSASSTK 154.56 6.3503e-17 0.0 4247.1 5105.3 7851.8 11093.0 8627.3 7137.5 8352.6 10589.0 6348.2 6574.1 True False 5597.589454832129 6755.488385417139 7747.680001725021 8535.680235141546 7429.548313037937 6691.190996682746 9095.96521886975 8952.713361013033 6683.752891892841 6343.942760000308 0.8823518222966844 1.0648722160628088 1.2212720534894366 1.3454850647393186 1.1711247396307807 1.054736975067288 1.4338031667343272 1.411222279220659 1.053564501564405 1.0 12.63116403864278 -4.951359322124078 2.244786169779342 1.2321974237297757 0.8544031518789902 0.3327485566375221 0.1439061494632814 0.4707667832174903 3.6754490992922815 0.03876365562379564 0.31055931492697936 1.1185120774516797e-05 4.951359322124078 -0.3777942718507855 FSGWYDADLSPAGHEEAK ddPTM_PC-9_Lapatinib_30min_R1 1 FSGWYDADLSPAGHEEAK 18 0 P18669 P18669 PGAM1 Phosphoglycerate mutase 1 0 106.36 0.0013204 0.0 13925.0 14769.0 15779.0 8290.2 12995.0 12302.0 15715.0 12584.0 14455.0 10639.0 False True 13726.426946467755 14734.80328790466 14481.711528701402 8899.888963296497 12230.659649153 11775.872137362652 16528.645805914453 13168.6985801506 12826.925682101879 12477.936974423592 1.1000558004582994 1.1808685456664059 1.1605854043328643 0.7132500333619949 0.9801828358503939 0.943735503833688 1.324629691574314 1.0553586387832286 1.0279684621258802 1.0 13.607091807115177 FSHDLK ddPTM_PC-9_Lapatinib_30min_R1 1 FSHDLK 6 0 P49736;H0Y8E6 P49736 MCM2 DNA replication licensing factor MCM2 0 118.01 0.017314 3385600.0 41279.0 34121.0 42773.0 37579.0 38592.0 35542.0 37206.0 36405.0 41184.0 35443.0 False True 40690.35389035849 34041.994920888 39256.369048554756 40342.68501986912 36322.09443479124 34021.95151244865 39132.34462964384 38096.50920298654 36545.4242332538 41569.275325171104 0.9788564648303983 0.8189220200399988 0.9443601973206439 0.9704928629208203 0.8737726157279777 0.818439851219817 0.9413766375173818 0.9164583434515221 0.8791450884669318 1.0 15.343229977309791 -10.660579591626423 4.125714325792066 1.0000258024579436 0.9032145521304246 0.21786244623613293 0.054139564586711125 38209937.46180282 0.4231552947831948 9729.647399072139 0.012953620313002233 2.1848438742867257e-11 10.660579591626423 -0.09681125032751903 FSHEEIAMATVTALR ddPTM_PC-9_AZD4547_30min_R2 2 FSHEEIAMATVTALR 15 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BR68;H3BU78 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ; 91.789 0.0031851999999999996 6941500.0 30743.0 34229.0 42873.0 43244.0 43925.0 39380.0 36726.0 41535.0 31858.0 41359.0 False True 40518.63450587557 45292.85486542284 42304.476007279445 33274.76391313988 37826.771950690425 36917.56237469235 39994.542852310726 35116.72012934901 33541.948840603945 39911.03399869984 1.0152238728567025 1.1348454381537278 1.0599694312269028 0.8337234238086605 0.9477772976746904 0.9249963901184569 1.0020923750964108 0.8798749771928481 0.8404179365960959 1.0 15.28450003563423 -5.654689967636597 7.206867426100101 0.9186778811944136 1.0799495364979883 0.5686424477543337 0.06050744419318264 0.15177373243257306 9.18328111237553 0.016246047371814502 0.028246178651589307 2.2146751486310656e-06 5.654689967636597 0.16127165530357468 FSHEEIAMATVTALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FSHEEIAMATVTALR 15 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BR68;H3BU78 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 74.783 0.010614 4768200.0 29423.0 33400.0 31368.0 41517.0 48372.0 30946.0 36166.0 31150.0 26759.0 27217.0 False True 34403.73276926065 36715.731267089875 32115.932083802447 39190.93708993009 38893.853841307435 29323.137282680473 32740.094660834657 30332.345506153157 27150.299751945622 32151.226650346536 1.0700597256649254 1.1419698435267676 0.998902232660423 1.218956200836203 1.2097160168813723 0.9120379014330521 1.0183155690105459 0.943427317284836 0.8444561088512307 1.0 14.972586160605394 -6.7713260826586055 24.999977468409465 0.9447783214031409 1.1265911330404557 0.6077808343441073 0.07400899996103659 149.05762880286431 376911.6426933964 0.026694767380835673 0.02382026080983918 1.6930661130692648e-07 6.7713260826586055 0.18181281163731478 FSHEEIAMATVTALR ddPTM_PC-9_Lapatinib_30min_R1 1 FSHEEIAMATVTALR 15 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BR68;H3BU78 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 67.648 0.024678 4213400.0 16914.0 14320.0 22051.0 19214.0 19808.0 21257.0 15815.0 15659.0 19702.0 19852.0 False True 16672.803258352273 14286.842919818171 20238.051899321556 20627.061656025046 18642.932384026346 20347.88766248723 16633.82331661069 16386.57430599001 17482.95328874239 23283.391748872742 0.7160813784426181 0.6136066031062619 0.8692054885131318 0.8859130954159072 0.8006965903036416 0.8739228322897743 0.7144072262330944 0.703788111402771 0.7508765680407719 1.0 14.507013614035113 -12.023583705416899 2.171635887323794 3.7887804844531154 0.7719715757923106 0.4040365583797044 0.08382548027969215 3873681.6423189254 218812.14200244553 53580470.65493218 0.023669893135030772 9.471446153513748e-13 12.023583705416899 -3.016808908660805 FSKEEPVS(ph)SGPEEAVGK ddPTM_PC-9_AZD4547_30min_R2 1 FSKEEPVSSGPEEAVGK 17 1 O00567 O00567 NOP56 Nucleolar protein 56 1 FSKEEPVS(0.5)S(0.5)GPEEAVGK 74.047 0.004654999999999999 59732000.0 242270.0 226890.0 309120.0 415270.0 331070.0 319150.0 244310.0 305410.0 228720.0 274020.0 True False 319306.8204709519 300227.75542422495 305020.8668245804 319535.91735754325 285106.6451841789 299193.50004781707 266053.11670881725 258215.90212361774 240809.6722588656 264426.6432051969 1.2075440530520505 1.1353914710903248 1.1535179024599354 1.2084104441381165 1.0782069527045888 1.1314801580551808 1.0061509441102658 0.9765124232327845 0.9106861144547966 1.0 18.01250802224864 -7.243624183477126 1.209561079688634 0.9486245738230252 1.1662894111629503 0.8401269896929668 0.03899375787196717 0.17133762567889047 0.48987308032467075 0.024489296340979048 0.014225582100184845 5.706578772015402e-08 7.243624183477126 0.21766483733992503 FSKEEPVSS(ph)GPEEAVGK ddPTM_PC-9_AZD4547_30min_R2 3 FSKEEPVSSGPEEAVGK 17 1 O00567 O00567 NOP56 Nucleolar protein 56 1 FSKEEPVS(0.04)S(0.96)GPEEAVGK;FSKEEPVS(0.016)S(0.984)GPEEAVGK;FSKEEPVS(0.033)S(0.967)GPEEAVGK 109.37 0.00021831 91564000.0 122198.0 125611.0 145321.0 213060.0 166942.0 146162.0 121765.0 163176.0 121609.0 149776.0 True False 161054.42212370213 166212.29929301556 143393.94858894547 163942.3087441862 143764.98492867747 137022.46703427559 132601.8491099386 137960.89861145156 128037.003470306 144532.38782826668 1.114313715726242 1.1500003687098073 0.992123293218722 1.1342946117999682 0.994690443359304 0.948039875997106 0.9174542197939471 0.9545327568750654 0.8858706715787433 1.0 17.14103329258503 -6.484902878716631 2.990478002926061 0.9370529646981423 1.0940644594640705 0.6978951022913478 0.04837634853328511 0.14560650052572777 2.6129839073230023 0.016032552970539835 0.01750295489896086 3.2741390627057835e-07 6.484902878716631 0.15701149476592824 FSKEEPVSS(ph)GPEEAVGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FSKEEPVSSGPEEAVGK 17 1 O00567 O00567 NOP56 Nucleolar protein 56 1 FSKEEPVS(0.183)S(0.817)GPEEAVGK;FSKEEPVS(0.103)S(0.897)GPEEAVGK;FSKEEPVS(0.447)S(0.553)GPEEAVGK 85.177 0.0015473 79613000.0 134296.0 94061.0 109635.0 159055.0 166599.0 153941.0 156798.0 167378.0 162639.0 127114.0 True False 157029.66033309366 103398.75445250719 112249.11419305285 150143.6640132678 133955.12189092836 145868.0629623575 141944.95832078595 162984.50485165027 165017.28769224082 150158.76196612962 1.0457575587131829 0.6885962104284677 0.7475362258139301 0.9998994534007597 0.8920899462473179 0.9714255835118037 0.9452992050693891 1.085414548692228 1.0989521059681002 1.0 17.196129134988027 -6.853600205768829 0.8076552180044648 1.06237220219629 0.8336055029715409 0.3618253718356097 0.10347571492117669 0.6531459087282427 0.91736266358788 0.07278303733782758 0.06329553096323325 1.4008763202188928e-07 6.853600205768829 -0.22876669922474913 FSKEEPVSS(ph)GPEEAVGK ddPTM_PC-9_Lapatinib_30min_R1 4 FSKEEPVSSGPEEAVGK 17 1 O00567 O00567 NOP56 Nucleolar protein 56 1 FSKEEPVS(0.254)S(0.746)GPEEAVGK;FSKEEPVS(0.053)S(0.947)GPEEAVGK;FSKEEPVS(0.35)S(0.65)GPEEAVGK;FSKEEPVS(0.073)S(0.927)GPEEAVGK 96.633 0.0007233 174529000.0 296900.0 224510.0 246703.0 208387.0 199335.0 203105.0 185397.0 184545.0 220524.0 154297.0 True False 292666.1515552085 223990.16088885328 226420.03164111983 223712.47513865412 187610.50720768838 194418.67261087973 194995.94950551208 193119.6344146449 195686.26489933123 180967.03086217062 1.617234643022413 1.2377401553294547 1.2511673013719689 1.23620570041313 1.0367109761035844 1.0743320022692655 1.0775219584280313 1.0671536881307957 1.0813365504591341 1.0 17.465367361004397 -1.5228787453968842 0.5151602461835313 1.0543008585371512 19.57564841455439 0.8907479120953378 0.05709192032453436 35.25774988375872 0.35894445820077225 0.03040669225173256 711.9018716457068 0.029999999991949244 1.5228787453968842 18.52134755601724 FSLS(ph)PSLGPQASR ddPTM_PC-9_AZD4547_30min_R2 1 FSLSPSLGPQASR 13 0 Q9NYF3 Q9NYF3 FAM53C Protein FAM53C 1 FSLS(0.5)PS(0.5)LGPQASR 113.52 0.00033546 8488400.0 16111.0 13195.0 24443.0 31013.0 22638.0 21921.0 26314.0 21676.0 15747.0 18191.0 True False 21233.962870382235 17460.02570771143 24118.869849227507 23863.431996073603 19495.10446032395 20550.276404663062 28655.89502302738 18326.47226492763 16579.354271862354 17554.13862690948 1.20962716096088 0.9946387047978656 1.3739705696669544 1.359419137746374 1.110570269192194 1.1706798517109052 1.6324295729953704 1.0439972393082397 0.9444698269869626 1.0 14.099523585157188 -7.97908383708494 24.978546708827004 0.9795674504959377 1.258561137092403 0.366560337705933 0.16327664090031951 244.7487404635295 292284.25401575415 0.09126438784820493 0.04383587968902651 1.0493398424141536e-08 7.97908383708494 0.2789936865964653 FSPNSSNPIIVSCGWDK ddPTM_PC-9_Lapatinib_30min_R1 2 FSPNSSNPIIVSCGWDK 17 0 D6R9L0;P63244;D6R9Z1;D6RFX4;D6RHH4;H0Y8W2;J3KPE3;H0YAM7;H0YAF8;D6RBD0;D6RAC2;D6REE5;H0Y8R5 D6R9L0 GNB2L1 Guanine nucleotide-binding protein subunit beta-2-like 1;Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed 0 ; 208.47 8.1293e-17 7940200.0 42978.0 36264.0 54241.0 38439.0 42140.0 39493.0 41830.0 38620.0 43070.0 36708.0 False True 42365.12583880009 36180.03293605354 49781.51435631488 41265.93228874501 39661.40805042765 37803.97645267953 43995.7527242381 40414.42618924157 38219.003052793334 43052.92888966457 0.9840242448399465 0.8403617098566096 1.1562863582148903 0.9584930306251813 0.9212243875921041 0.8780814088064258 1.021899179890636 0.9387149081730324 0.8877213243898099 1.0 15.393823767017352 -5.9907528892397455 24.999600374744297 0.9391516409395366 0.9914297991377318 0.07461716415069719 0.08203657767648383 578.3534531951768 1563563.6494260354 0.023091341880882132 0.03419813850361415 1.0215205569895893e-06 5.9907528892397455 0.052278158198195146 FSPPS(ph)PLPQAVFSTSSR ddPTM_PC-9_AZD4547_30min_R2 2 FSPPSPLPQAVFSTSSR 17 0 Q99594;A0A1X7SBS4 Q99594 TEAD3 Transcriptional enhancer factor TEF-5 1 FSPPS(0.996)PLPQAVFS(0.002)T(0.002)SSR;FS(0.019)PPS(0.981)PLPQAVFSTSSR 154.52 2.2209e-05 132208000.0 60785.0 67678.0 76047.0 123398.0 113892.0 92742.0 68117.0 94260.0 76850.0 78046.0 True False 80113.36559345695 89553.58998457708 75038.56709177293 94950.49758009517 98080.06171902177 86942.82807906835 74179.281039886 79694.28287931712 80912.13410761554 75313.63329535357 1.0637299262841367 1.189075417904477 0.9963477236252575 1.2607345234259608 1.3022882767371782 1.1544102212956473 0.9849382879854031 1.0581654262619913 1.0743358216474115 1.0 16.20062342515415 -7.2000983586007 7.655222647759625 1.0343645592008799 1.166222103739567 0.36130373116299297 0.08557335715814247 0.3578202538821503 40.322505374561196 0.03470384753944753 0.026789099667881497 6.308144620422012e-08 7.2000983586007 0.13185754453868714 FSPPS(ph)PLPQAVFSTSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FSPPSPLPQAVFSTSSR 17 0 Q99594;A0A1X7SBS4 Q99594 TEAD3 Transcriptional enhancer factor TEF-5 1 FS(0.001)PPS(0.999)PLPQAVFSTSSR;FSPPS(0.998)PLPQAVFS(0.001)T(0.001)SSR 106.87 0.00062803 69458000.0 34929.0 39854.0 44411.0 51338.0 64777.0 55932.0 54152.0 59287.0 55603.0 39314.0 True False 40841.78982080362 43810.44173408979 45469.926669655426 48461.69830004169 52084.41185558529 52998.82745734136 49022.33053347115 57730.77906976899 56416.08868445872 46441.31699054721 0.8794278988495668 0.943350545872915 0.9790834889309986 1.0435039624286648 1.1215102247463544 1.141199924802496 1.0555758042660437 1.243090911515702 1.2147822744979822 1.0 15.503121264517585 -5.683037425695856 0.8526896664303785 1.1499788848180594 0.8679764723595472 0.6411221769795938 0.06683338016607931 0.527806420794207 0.6618449391275931 0.028903648403820176 0.10994304630486117 2.0747347177243875e-06 5.683037425695856 -0.2820024124585122 FSPPS(ph)PLPQAVFSTSSR ddPTM_PC-9_Lapatinib_30min_R1 2 FSPPSPLPQAVFSTSSR 17 0 Q99594;A0A1X7SBS4 Q99594 TEAD3 Transcriptional enhancer factor TEF-5 1 FSPPS(0.995)PLPQAVFS(0.001)T(0.002)S(0.001)S(0.001)R;FS(0.001)PPS(0.999)PLPQAVFSTSSR 173.77 6.6565e-06 83959000.0 110304.0 92267.0 104302.0 95326.0 126745.0 133006.0 132833.0 124070.0 140983.0 109774.0 True False 108731.04473272363 92053.36143036769 95726.69217736326 102336.5920382138 119290.10829025735 127317.64343212942 139710.44278313924 129834.74513980326 125104.00992319413 128748.28963533936 0.8445241877829085 0.714987062671631 0.743518165938321 0.7948578760002729 0.926537421414522 0.9888880372138377 1.0851440681569329 1.008438601456696 0.9716945388364605 1.0 16.974193741287976 -6.403478159023647 2.0037994765814684 1.0174382632044905 0.7613840481069212 0.8801092895363651 0.04126274158911353 0.10420579944767515 0.827014923966307 0.015054555862038091 0.017699988274643613 3.949315602367715e-07 6.403478159023647 -0.2560542150975693 FSPPSPLPQAVFSTSS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FSPPSPLPQAVFSTSSR 17 0 Q99594;A0A1X7SBS4 Q99594 TEAD3 Transcriptional enhancer factor TEF-5 1 FS(0.002)PPS(0.307)PLPQAVFS(0.095)T(0.095)S(0.031)S(0.47)R 73.252 0.010915000000000001 1858800.0 5755.6 8540.8 6634.3 9814.2 10123.0 9729.0 10366.0 9914.9 7874.7 6309.4 True False 6729.9094017182615 9388.674179819192 6792.486872722861 9264.342192065702 8139.470818563536 9218.794113074335 9384.057436659068 9654.64438070492 7989.852590031246 7453.24427481708 0.9029503332471187 1.2596761670003915 0.911346337550377 1.242994573969343 1.0920708510876358 1.2368833991155597 1.2590567396758743 1.295361325178339 1.0719966091849762 1.0 12.863652828407334 -6.746500363949459 24.0564658256606 1.1965195077597046 1.091173941176483 0.08422565683682459 0.13734814591723862 323.9660783021859 521684.30056626693 0.04279665679685019 0.042608966648763756 1.792667050065812e-07 6.746500363949459 -0.1053455665832217 FSPS(ph)SPESANECSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FSPSSPESANECSK 14 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5 Q8NEV8-2 EXPH5 Exophilin-5 1 FSPS(0.945)S(0.054)PESANECSK 194.77 1.4094000000000002e-07 13363000.0 47900.0 36097.0 43134.0 54249.0 68200.0 60031.0 60059.0 62851.0 39721.0 43956.0 True False 56008.5239318759 39680.47160323782 44162.47814660592 51209.60440763102 54836.69957779638 56882.86868146427 54369.776730494574 61201.227846139074 40301.844480250795 51924.874844495454 1.0786453332744692 0.7641900288074424 0.8505071659558863 0.9862248982013626 1.0560776456760128 1.0954839824230103 1.04708536887804 1.178649501408033 0.7761567957736385 1.0 15.664138213268513 -5.931247134264955 4.371325892629768 1.0380143637702954 0.8855081192356917 0.1746515480123907 0.121221376618029 0.3010591888547087 11.309320014881417 0.03372333946707263 0.0508828998609621 1.171528520252738e-06 5.931247134264955 -0.1525062445346037 FSPS(ph)SPESANECSK ddPTM_PC-9_Lapatinib_30min_R1 1 FSPSSPESANECSK 14 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5 Q8NEV8-2 EXPH5 Exophilin-5 1 FSPS(0.941)S(0.059)PESANECSK 194.01 1.5395999999999998e-07 23381000.0 30224.0 25984.0 32798.0 30408.0 41995.0 26617.0 32775.0 31624.0 34827.0 23561.0 True False 29793.000217597208 25923.835644452207 30101.47504394123 32644.30575811436 39524.936665346664 25478.652957257516 34471.929130693345 33093.366489087945 30904.416515431494 27633.487456940904 1.07814839744789 0.9381311600588701 1.0893114772735797 1.1813313758888169 1.4303274867833917 0.9220208993511552 1.2474693678967683 1.1975819751544114 1.118368304528606 1.0 14.754130027090124 -5.539894301769952 4.302963342871526 1.169394849511862 1.0076950836835352 0.16095881569809656 0.1332758378146714 0.3092399928084203 13.6464697038386 0.035465306057039694 0.06835130705162612 2.884733501739273e-06 5.539894301769952 -0.1616997658283268 FSPSS(ph)PESANECSK ddPTM_PC-9_AZD4547_30min_R2 2 FSPSSPESANECSK 14 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5 Q8NEV8-2 EXPH5 Exophilin-5 1 FS(0.001)PS(0.017)S(0.981)PESANECSK;FSPS(0.124)S(0.875)PES(0.001)ANECSK 207.31 7.210600000000001e-11 47359000.0 203750.0 191041.0 231683.0 292240.0 263020.0 231579.0 229405.0 277870.0 226059.0 262121.0 True False 268538.26173672534 252791.26723962874 228610.73204101704 224868.58306299153 226504.21305567672 217098.3285213025 249821.6005836287 234931.57631737596 238008.0172314049 252944.22357342351 1.0616501058731442 0.9993952961975809 0.9037989830776149 0.8890046188294064 0.8954709850882524 0.8582853779156738 0.9876548950370143 0.9287880663903798 0.9409505932532869 1.0 17.9484597674775 -5.030322896253635 3.0472718363411806 0.9205744725559459 1.0585902010991475 0.5256221296770303 0.041595550279591685 0.20073240290511438 3.547734267318238 0.011034719642470193 0.050102744507856393 9.32560687745102e-06 5.030322896253635 0.13801572854320154 FSPSS(ph)PESANECSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FSPSSPESANECSK 14 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5 Q8NEV8-2 EXPH5 Exophilin-5 1 FSPS(0.002)S(0.997)PES(0.001)ANECSK;FSPS(0.183)S(0.812)PES(0.005)ANECSK;FS(0.002)PS(0.02)S(0.965)PES(0.013)ANECSK 235.71 6.558899999999998e-106 20173800.0 114861.0 120383.0 125378.0 155656.0 171237.0 143869.0 149714.0 152500.0 141495.0 125968.0 True False 134304.69869184121 132333.8286564693 128367.48701871288 146935.09896356065 137684.33908508954 136324.2563731003 135532.00608450448 148497.03658710603 143564.09669275922 148805.00123786068 0.9025550053735013 0.8893103562086421 0.8626557303240165 0.9874338748110284 0.9252668790681634 0.9161268454626048 0.9108027617153829 0.9979304146487498 0.964780051063445 1.0 17.183063489725555 -6.928889576551125 0.24546268425099313 1.0135822379352597 0.8588288717655583 0.49504097865142005 0.032739557341116596 2.9382134492155876 0.43806501631640693 0.07181829818718896 0.15354239219790092 1.1779054289621771e-07 6.928889576551125 -0.15475336616970137 FSPSS(ph)PESANECSK ddPTM_PC-9_Lapatinib_30min_R1 1 FSPSSPESANECSK 14 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5 Q8NEV8-2 EXPH5 Exophilin-5 1 FS(0.001)PS(0.461)S(0.538)PESANECSK 197.47 9.4751e-08 22481000.0 48381.0 47493.0 60466.0 52884.0 60400.0 59111.0 49355.0 48791.0 57748.0 47878.0 True False 47691.07806801122 47383.032876461206 55494.71888550983 56773.26577585242 56847.39075096891 56582.96032447111 51910.36040413029 51058.0079803026 51243.812126601144 56153.64850657511 0.8492961603808701 0.8438104047845272 0.9882655955830167 1.0110343189758144 1.0123543574254585 1.007645305858367 0.9244343294639533 0.9092553972574755 0.912564249865277 1.0 15.77709214235945 -5.2570191427319735 24.75062930374824 0.9700494431373617 0.8465532645571578 0.6184854069714376 0.038997473085814735 234.4436530594409 1312726.8741919438 0.01161391244152088 0.02854817504941295 5.5332571931482105e-06 5.2570191427319735 -0.1234961785802039 FSS(ph)GGEEDDFDR ddPTM_PC-9_AZD4547_30min_R2 2 FSSGGEEDDFDR 12 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 FS(0.042)S(0.958)GGEEDDFDR;FS(0.059)S(0.941)GGEEDDFDR 196.02 1.3168e-05 11309000.0 35784.0 37805.0 50817.0 67531.0 55847.0 56183.0 47189.0 50586.0 43028.0 41341.0 True False 47162.56764656186 50024.72693293144 50143.13337676206 51962.77129354941 48093.60803939007 52669.86812842408 51388.729582793945 42769.09605063799 45302.37223659698 39893.66417322108 1.1822069650403306 1.2539516730205724 1.2569197243711951 1.3025319275743494 1.2055450166363326 1.3202564672858286 1.2881426323653924 1.0720774072025971 1.1355781218764693 1.0 15.283872018436018 -7.765658733346615 24.999994495501568 1.0778707611956857 1.260302623222324 0.7520260176078888 0.049728783427768715 53.22675763806166 315363.7772180793 0.025453236348194835 0.012912037576731249 1.715304656764144e-08 7.765658733346615 0.1824318620266383 FSS(ph)GGEEDDFDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FSSGGEEDDFDR 12 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 FS(0.003)S(0.997)GGEEDDFDR 215.02 9.3576e-11 6332300.0 22559.0 22051.0 26133.0 29645.0 28415.0 24134.0 21819.0 22779.0 19373.0 14204.0 True False 26377.793139440237 24240.077550017933 26756.109829954403 27984.086760386766 22847.284728784245 22868.370554521127 19752.14636411964 22181.075386345532 19656.2934748848 16779.07276119786 1.572065007098588 1.4446613287281218 1.5946119437439215 1.667796972971049 1.361653593970897 1.3629102680456195 1.1771893861618568 1.321948816959658 1.1714767409758544 1.0 14.034375371859769 -7.40819508912238 0.4927051932327201 1.0299339039979831 1.5933123462911056 0.8071941350829126 0.0879716106104836 0.4349282473267853 0.23335151157181244 0.09364756969453684 0.07854897293546856 3.906653658530314e-08 7.40819508912238 0.5633784422931225 FSS(ph)GGEEDDFDR ddPTM_PC-9_Lapatinib_30min_R1 2 FSSGGEEDDFDR 12 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 FS(0.037)S(0.963)GGEEDDFDR;FS(0.008)S(0.992)GGEEDDFDR 225.97 2.0943e-15 11511900.0 56758.0 54712.0 52070.0 47656.0 39889.0 34932.0 30715.0 29013.0 39754.0 27060.0 True False 55948.62051185754 54585.31772549529 47789.005596012525 51160.78121575567 37542.807444791375 33438.03979046919 32305.272410350768 30361.04989716379 35276.4858918214 31737.284944816474 1.762867258782179 1.7199113856275376 1.505768552007714 1.6120087557808425 1.182924358843843 1.0535885425804357 1.0178965360938053 0.9566366483445062 1.111515555069022 1.0 14.953891093601893 -6.294024098490746 1.4732380956617197 1.01061243316773 1.6943720942487084 0.943843718064388 0.07215446507647154 0.08507890893013925 0.370092312636958 0.02736934897102362 0.03669513136103171 5.081312461721979e-07 6.294024098490746 0.6837596610809784 FSS(ph)LWGLDTTSK ddPTM_PC-9_AZD4547_30min_R2 2 FSSLWGLDTTSK 12 0 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 FS(0.021)S(0.979)LWGLDTTSK;FS(0.053)S(0.947)LWGLDTTSK 128.54 0.00020173 5105100.0 86831.0 87810.0 113433.0 147391.0 120833.0 115438.0 104049.0 115737.0 92247.0 117173.0 True False 114441.45180300185 116192.86528185983 111928.80430419456 113412.28211824993 104057.42367940271 108219.6436112172 113309.15943037867 97852.50602167983 97122.98809401708 113070.8089346852 1.0121219869321745 1.027611515090319 0.9899000932137108 1.0030199941680966 0.9202854800438455 0.9570962181205384 1.0021079755061375 0.8654090913792245 0.8589572234343853 1.0 16.786866996683365 -6.241157712710156 0.7028341562547715 0.917631483388183 1.0271640532404487 0.3609289626228467 0.04662423402370953 0.8744400139505817 0.9208984716912262 0.029623968186581646 0.055413338197598964 5.739080114249474e-07 6.241157712710156 0.10953256985226567 FSS(ph)LWGLDTTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FSSLWGLDTTSK 12 0 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 FS(0.003)S(0.997)LWGLDTTSK 156.52 0.00037460000000000005 2471800.0 56854.0 47577.0 52870.0 60359.0 59002.0 51363.0 53953.0 47179.0 41803.0 43840.0 True False 66478.25928231452 52300.130134560946 54130.62131059155 56977.28091651827 47440.98164940092 48669.433860606165 48842.18125410636 45940.60124028255 42414.289791493815 51787.84496275095 1.2836652950152654 1.0098919963203425 1.0452379578552782 1.1002056748547828 0.9160640239717146 0.9397848838006729 0.9431205582938759 0.8870923529126555 0.8190008644306559 1.0 15.660325904686687 -1.5228787452803376 0.39360005473746285 0.9006687555481379 6.14465654099995 0.6852496270038544 0.06911191664319821 41.873301034260535 0.5609443347141775 0.05120545543529138 169.4000611189329 0.029999999999999995 1.5228787452803376 5.243987785451813 FSS(ph)LWGLDTTSK ddPTM_PC-9_Lapatinib_30min_R1 1 FSSLWGLDTTSK 12 0 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 FS(0.011)S(0.978)LWGLDT(0.005)T(0.005)SK 84.352 0.010256 2666900.0 44089.0 39933.0 35627.0 37255.0 31694.0 32562.0 30158.0 27625.0 30039.0 23193.0 True False 43460.28277506761 39840.5375919762 32697.88558419702 39994.85697903677 29829.82123280145 31169.399165729392 31719.43367577269 28908.558350020678 26655.691495306717 27201.879147270094 1.5976941350182112 1.4646244612837525 1.2020451016332998 1.4702975762264772 1.0966088435031918 1.1458546300047607 1.1660750900349457 1.0627412243658123 0.9799209588055908 1.0 14.731418698039926 -1.5228787452805557 0.23210317845299266 0.9596892114840541 4.645133955627832 0.8051423680752118 0.09044880988613292 20.85646461823423 0.27423838648076 0.12775720158856585 29.28699394889573 0.029999999999984935 1.5228787452805557 3.685444744143778 FSS(ph)PIVK ddPTM_PC-9_AZD4547_30min_R2 4 FSSPIVK 7 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 FS(0.043)S(0.957)PIVK;FS(0.077)S(0.923)PIVK;FS(0.137)S(0.863)PIVK;FS(0.106)S(0.894)PIVK 99.13600000000001 0.011939 110071000.0 696380.0 634200.0 757770.0 979840.0 839390.0 763140.0 631990.0 778220.0 633090.0 711640.0 True False 917814.3543961773 839192.7475430531 747721.4746818767 753953.0263770934 722855.1874260663 715420.7351605553 688235.8856731432 657963.9807165527 666553.8449211492 686725.7002063594 1.3365079450505148 1.2220203019792004 1.088821161720303 1.0978954568767885 1.0526112350372938 1.041785293524872 1.0021991101633885 0.9581176014219887 0.970626037034658 1.0 19.389374430867143 -1.5228787464578841 0.37850358587899546 0.973120432757526 6.268186244275774 0.9614858907217254 0.02218226218819198 12.263219958695357 0.16772487539243905 0.018419238812174978 47.565640105174595 0.029999999918657965 1.5228787464578841 5.295065811518247 FSS(ph)PIVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 FSSPIVK 7 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 FS(0.018)S(0.982)PIVK;FS(0.016)S(0.984)PIVK;FS(0.032)S(0.968)PIVK;FS(0.07)S(0.93)PIVK 106.6 0.010031 88365000.0 487951.0 472632.0 456000.0 473461.0 550171.0 455961.0 486296.0 436434.0 411096.0 321094.0 True False 570551.4668284511 519551.78144392755 466872.76938963064 446934.5151512724 442368.94198556826 432049.60248653434 440230.52240184724 424978.06994004716 417107.5012827772 379305.80042129365 1.5041991611906318 1.3697438343069448 1.2308611386144812 1.1782960204005943 1.1662593651197282 1.139053507767765 1.1606216459460539 1.1204101531482658 1.0996602235438986 1.0 18.533001908223063 -1.5228787452803376 0.39164870076612884 1.0862844828898883 7.696573950522554 0.9384518686059898 0.03378788503253764 15.800422202987102 0.21227513481518415 0.024982507666955398 80.04828914492442 0.029999999999999995 1.5228787452803376 6.610289467632666 FSS(ph)PIVK ddPTM_PC-9_Lapatinib_30min_R1 1 FSSPIVK 7 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 FS(0.003)S(0.997)PIVK 110.41 0.009469400000000001 16968000.0 318960.0 285990.0 356090.0 274880.0 280310.0 283040.0 252890.0 238670.0 304360.0 181470.0 True False 314411.57190989907 285327.80772617366 326813.65474715084 295095.5921727992 263822.7169106637 270935.03899846546 265983.40679972677 249759.47950767222 270079.7717471134 212836.84770642468 1.4772421941880145 1.3405940315360194 1.5355125687537876 1.3864873275131273 1.239553769723963 1.2729705495928891 1.2497056297629887 1.1734785691440826 1.2689521323847381 1.0 17.69938841569583 -5.478896990182079 0.09371388947590413 0.7191362073361715 2.07692290502533 0.7823610045520318 0.06753825645890746 23.860845566514563 0.4659668215963427 1.893934235474783 5.284654005510861 3.319731885610374e-06 5.478896990182079 1.3577866976891584 FSS(ph)PTEELDYR ddPTM_PC-9_AZD4547_30min_R2 1 FSSPTEELDYR 11 0 D6RAA5;Q4VXL8;E7EMZ9;E9PBC6;O95359-6;O95359-1;O95359-5;O95359-3;O95359;H0Y911;Q4VXL4;E9PGB3;O95359-2 D6RAA5 TACC2 Transforming acidic coiled-coil-containing protein 2 1 FS(0.033)S(0.965)PT(0.002)EELDYR 132.5 0.0001051 7042600.0 15397.0 15273.0 15645.0 23452.0 23088.0 20524.0 18521.0 20354.0 15121.0 17610.0 True False 20292.925722504824 20209.69857020663 15437.53707773859 18045.503729788103 19882.62972788936 19240.63103550498 20169.333120068794 17208.756988389774 15920.265189866672 16993.479260066826 1.1941595603786332 1.1892619669532676 0.9084388689028172 1.0619075383928847 1.1700152407642492 1.1322361207524325 1.1868866175901331 1.0126682549834767 0.9368455362332944 1.0 14.052693640980335 -7.938744141702141 6.359154080317186 0.9701831049524675 1.114700258017515 0.374289624095295 0.0823602914206731 0.22704391635839533 17.62158436012703 0.049639982271018505 0.023344758788044425 1.1514785660594246e-08 7.938744141702141 0.14451715306504742 FSS(ph)PTEELDYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FSSPTEELDYR 11 0 D6RAA5;Q4VXL8;E7EMZ9;E9PBC6;O95359-6;O95359-1;O95359-5;O95359-3;O95359;H0Y911;Q4VXL4;E9PGB3;O95359-2 D6RAA5 TACC2 Transforming acidic coiled-coil-containing protein 2 1 FS(0.004)S(0.971)PT(0.025)EELDYR;FS(0.023)S(0.903)PT(0.074)EELDYR;FS(0.006)S(0.882)PT(0.112)EELDYR 145.23 0.00010116 10626600.0 54824.0 56048.0 61200.0 69227.0 72837.0 55126.0 64287.0 67340.0 62712.0 50632.0 True False 64104.620376642226 61612.07503167223 62659.24010229248 65348.43562696224 58565.11271477945 52235.09551622327 58197.26996242538 65572.3963526278 63629.04436055207 59811.18079730852 1.0717832271842878 1.0301096586015694 1.0476175067440254 1.0925789251414157 0.9791666363058135 0.8733332935398899 0.9730165695883441 1.0963233876763476 1.0638319376469383 1.0 15.868127579241413 -6.272758492465635 24.5630924926105 0.9949844344955736 1.0574282235727248 0.22282717033841482 0.057315532227019114 1060.3745285938744 2301067.3689669007 0.020262454525757912 0.02318958996780835 5.336315610478169e-07 6.272758492465635 0.0624437890771512 FSS(ph)PTEELDYR ddPTM_PC-9_Lapatinib_30min_R1 3 FSSPTEELDYR 11 0 D6RAA5;Q4VXL8;E7EMZ9;E9PBC6;O95359-6;O95359-1;O95359-5;O95359-3;O95359;H0Y911;Q4VXL4;E9PGB3;O95359-2 D6RAA5 TACC2 Transforming acidic coiled-coil-containing protein 2 1 FS(0.045)S(0.954)PT(0.002)EELDYR;FS(0.028)S(0.964)PT(0.008)EELDYR;FS(0.056)S(0.888)PT(0.056)EELDYR 171.92 0.00018391 15352900.0 62136.0 54720.0 62899.0 53580.0 67907.0 64636.0 58842.0 53876.0 63685.0 59192.0 True False 61249.92924565316 54593.2992019868 57727.6870171614 57520.45193764032 63912.84377029872 61871.668953875174 61888.55084388282 56379.27564400774 56512.12466721955 69423.2583316177 0.8822681435244285 0.7863834183813174 0.8315323769652317 0.8285472811270161 0.9206258148386367 0.8912239275536383 0.8914671009570964 0.8121093276074411 0.8140229373457974 1.0 16.08313145817828 -6.214335303302241 21.229154005473156 0.8791573795639239 0.8288647642957244 0.18914578491758172 0.05479182638586686 143.35572015233825 64607.05807880943 0.016131509643303163 0.020825391269755533 6.104705203659677e-07 6.214335303302241 -0.0502926152681995 FSSS(ph)IENSDSPVR ddPTM_PC-9_AZD4547_30min_R2 1 FSSSIENSDSPVR 13 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 FS(0.011)S(0.05)S(0.925)IENS(0.014)DSPVR 91.969 0.020579 0.0 13798.0 11345.0 17194.0 24306.0 20042.0 21199.0 17687.0 26527.0 22509.0 18223.0 True False 18185.476983770975 15012.04938643321 16965.99632563997 18702.627223956566 17259.514250102155 19873.423178798963 19261.108735740872 22427.86167981801 23698.779786965748 17585.018316649508 1.0341460359215522 0.853684034677393 0.9647983311781116 1.0635546058117498 0.9814896941995696 1.1301337775680786 1.095313544115245 1.2753959805991952 1.3476687575882549 1.0 14.102059217232354 -6.942860559077105 1.0950907405337473 1.2208600834093164 0.9588715303133047 0.46812350823326787 0.10190682199378803 0.3983896844898732 0.9935960318732896 0.05924949209493405 0.04487601490949692 1.140615951574511e-07 6.942860559077105 -0.26198855309601166 FSSS(ph)IENSDSPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FSSSIENSDSPVR 13 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 FS(0.012)S(0.175)S(0.813)IENSDSPVR;FS(0.002)S(0.032)S(0.967)IENSDSPVR 116.19 0.00098646 0.0 11417.0 16151.900000000001 16542.2 15646.1 22384.0 15459.9 16903.7 15341.1 15134.2 12462.8 True False 13349.672603971341 17755.353887811638 16936.628784642842 14769.499742340604 17998.015884888493 14649.155628401471 15302.459163809943 14938.412380239062 15355.50904390654 14722.206984529483 0.9067711531293888 1.2060252859146372 1.1504137119142759 1.0032123415912313 1.2225080046627061 0.9950380159574732 1.0394133963671484 1.0146856647197513 1.043016788178739 1.0 13.845706339461309 FSSSIENS(ph)DSPVR ddPTM_PC-9_Lapatinib_30min_R1 1 FSSSIENSDSPVR 13 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 FSSSIENS(0.902)DS(0.098)PVR 102.9 0.0016326000000000001 2794600.0 9688.1 8176.1 14455.0 10721.0 10886.0 10903.0 10549.0 8814.6 13325.0 8585.5 True False 9549.945917420051 8157.168742788089 13266.565697913606 11509.458104207586 10245.706882699462 10436.704106134373 11095.175603346577 9224.15849527936 11824.198181529398 10069.49223554035 0.9484039208763122 0.8100873958666256 1.3175009610801585 1.143002828244394 1.0174998543161056 1.0364677644119875 1.1018604854955913 0.9160500131995357 1.1742596255048292 1.0 13.2977033153532 -5.222478612812481 24.99905340175692 1.0833860360606 0.8792456062831572 0.3714549767863108 0.10863975986710178 586.3073828985079 376200.5411999241 0.027663454704826586 0.07318822117550756 5.991304425543031e-06 5.222478612812481 -0.20414042977744284 FSSSIENSDS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 4 FSSSIENSDSPVR 13 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 FSSSIENS(0.002)DS(0.998)PVR;FSSSIENS(0.011)DS(0.989)PVR;FSSSIENS(0.004)DS(0.996)PVR;FSSSIENS(0.094)DS(0.906)PVR 160.63 0.00029129 47150700.0 59861.5 57698.3 79290.0 106698.0 92504.1 90443.7 81079.7 93990.0 85203.5 83516.4 True False 78896.21180345019 76348.14712324715 78238.56279283435 82100.4245676672 79661.50245199454 84788.24114139058 88295.6362278087 79466.00517533449 89707.18306360726 80592.51625641386 0.9789520847374129 0.9473354434093758 0.9707919100566341 1.018710277098878 0.9884478876244887 1.0520609738952382 1.095581082825191 0.9860221378682947 1.1130956971016277 1.0 16.298358257247706 -6.2309798246978 1.1072040023824272 1.0506519026176462 0.9618999364046213 0.4326181564737879 0.039216131031090416 0.45135895201463805 1.1478923438136375 0.01598890994065358 0.02479516382287632 5.875166451872636e-07 6.2309798246978 -0.08875196621302484 FSSSIENSDS(ph)PVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FSSSIENSDSPVR 13 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 FSSSIENS(0.004)DS(0.996)PVR;FSSSIENS(0.005)DS(0.995)PVR 149.6 0.00012269 23336000.0 88977.0 102725.0 127234.0 125607.0 159940.0 120634.0 141993.0 152689.0 138368.0 111118.0 True False 104039.04872414444 112922.85911412568 130267.7410976318 118569.64701338863 128600.9051388969 114307.74067597998 128542.39509970398 148681.07553736836 140391.3702334623 131262.8137903959 0.7926010857140154 0.8602806526336089 0.992419233871117 0.9032995986412719 0.9797207710650663 0.870831101171652 0.9792750238080682 1.132697610572225 1.069544116718716 1.0 17.00209873904045 -7.5447144562561235 4.899066727696271 1.0747325534516028 0.9069567363012363 0.5941226784407887 0.06187628184869601 0.1321236873635862 8.423961486993125 0.03015785408518951 0.017585693764247262 2.852893396362824e-08 7.5447144562561235 -0.1677758171503665 FSSSIENSDS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 3 FSSSIENSDSPVR 13 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 FSS(0.001)S(0.001)IENS(0.077)DS(0.921)PVR;FSSSIENS(0.008)DS(0.992)PVR;FSSSIENS(0.083)DS(0.916)PVR 133.25 4.6228e-05 36070500.0 94706.0 109100.4 128400.0 117326.8 145061.0 155759.8 150785.4 159108.9 177292.0 141637.6 True False 93355.47507304665 108847.78472690877 117843.4476383334 125955.40426273155 136528.79718089916 149098.31644782788 158592.33021337152 166501.68034959663 157323.5079924735 166119.47043976083 0.5619779236347838 0.6552379708336462 0.7093897381587575 0.7582218022324253 0.8218711317792696 0.8975366707654823 0.9546883925980317 1.0023008134376061 0.947050382330246 1.0 17.341861652256362 -5.927143181614019 0.5080981186213798 1.0079635391645847 0.5064951825943886 0.9783443857844666 0.021554196194376662 0.21409549624430058 0.09270870764558459 0.017091205638266722 0.056916197720786994 1.182651585585901e-06 5.927143181614019 -0.5014683565701961 FSSVSS(ph)PQPR ddPTM_PC-9_AZD4547_30min_R2 3 FSSVSSPQPR 10 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 FSSVS(0.204)S(0.795)PQPR;FSS(0.008)VS(0.225)S(0.768)PQPR;FS(0.018)S(0.107)VS(0.14)S(0.734)PQPR 145.23 0.00013692 153036000.0 863240.0 1075500.0 1618690.0 2118450.0 1963640.0 1764180.0 1611710.0 2168800.0 1613650.0 1632510.0 True False 1137732.363492565 1423134.342451205 1597225.112966744 1630074.0822262333 1691022.4808936566 1653865.5457131756 1755149.067704017 1833661.7940660175 1698944.2446682344 1575356.3217973704 0.7222063654745059 0.9033729847400549 1.0138818062090378 1.0347335772052089 1.0734222204182475 1.0498358516289392 1.1141283044470318 1.1639663793483488 1.0784507740635203 1.0 20.587246750666203 -4.121869651845406 0.739973248707147 1.0924245740340883 9.889335237809348e-17 0.8823798116216126 0.04050286970698653 2.003213958308973 0.4143003892718101 0.015793806311563997 2.2818425247866605 7.553188933370304e-05 4.121869651845406 -1.0924245740340883 FSSVSS(ph)PQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 FSSVSSPQPR 10 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 FSS(0.001)VS(0.021)S(0.978)PQPR;FSSVS(0.026)S(0.974)PQPR;FS(0.082)S(0.056)VS(0.267)S(0.595)PQPR;FS(0.02)S(0.02)VS(0.111)S(0.848)PQPR 138.25 0.00011882 126848000.0 1098490.0 1411880.0 1627670.0 1618920.0 2246490.0 1706200.0 1948550.0 1706320.0 1650490.0 1584220.0 True False 1284442.6608335334 1552042.1156101448 1666479.8257728496 1528217.161009457 1806306.4110634008 1616723.8684065612 1763969.2377196641 1661530.9079954852 1674625.2938296935 1871426.5453213812 0.6863441496246144 0.8293363795070096 0.890486367172196 0.8166054739525004 0.9652029440210824 0.8638991855963656 0.9425800024743887 0.8878419044281268 0.8948389120675367 1.0 20.835706991978135 -3.836921005312672 0.7474549183136978 0.914186608632271 1.5917643147381404e-15 0.6852385791767688 0.04702762602369496 5.5237808549581775 0.8233511658952339 0.016815135972915906 5.884307177742358 0.0001455723841007892 3.836921005312672 -0.9141866086322694 FSSVSS(ph)PQPR ddPTM_PC-9_Lapatinib_30min_R1 4 FSSVSSPQPR 10 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 FS(0.001)S(0.006)VS(0.207)S(0.785)PQPR;FS(0.004)S(0.003)VS(0.031)S(0.962)PQPR;FS(0.028)S(0.058)VS(0.285)S(0.63)PQPR;FS(0.033)S(0.179)VS(0.121)S(0.666)PQPR 105.13 0.0025043 169024000.0 1554330.0 1421250.0 1241970.0 1155260.0 1369660.0 1154270.0 1167270.0 1171070.0 1422590.0 946140.0 True False 1532164.9691707839 1417959.1829463379 1139860.0207428408 1240221.6742343856 1289099.2916551656 1104904.5628347902 1227705.5291040256 1225482.1874012188 1262362.9336631831 1109679.0383476967 1.3807280449779114 1.2778101901047603 1.0271979386400625 1.1176399944267361 1.161686620281324 0.9956974266000234 1.1063609266081744 1.1043573367177884 1.1375928444524208 1.0 20.081711023608115 -5.087779635739064 3.7837069603768825 1.087476521704261 1.3650528054774909 0.7710862470605976 0.05510283104698885 0.0991899439767575 2.562757459025353 0.013994144728073584 0.04705598896632622 8.169968164847518e-06 5.087779635739064 0.27757628377322985 FSTLTDDPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 FSTLTDDPSPR 11 0 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-4 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 FSTLT(0.001)DDPS(0.998)PR;FSTLT(0.018)DDPS(0.982)PR;FST(0.001)LT(0.009)DDPS(0.99)PR 103.44 0.0029043000000000003 9590500.0 61272.0 54479.0 75865.0 99038.0 87635.0 74404.0 67427.0 93910.0 66005.0 73409.0 True False 80755.22146322764 72088.27135508982 74858.98053068962 76206.31922184688 75468.39294021088 69751.5061179943 73427.872376593 79398.3673371171 69493.88954812182 70838.97325396058 1.1399829465867175 1.0176357454624654 1.0567485254524673 1.0757682631655903 1.065351309788944 0.9846487450902534 1.0365462541834298 1.1208288840165817 0.9810120948391421 1.0 16.11225568124749 -4.75244313072537 24.99641025951057 1.0423597324679712 1.1399831344312075 0.3447201023632983 0.04188400708505984 424.1423948010906 1178409.3496011966 0.010151000529799779 0.12186328687635459 1.7683037554863634e-05 4.75244313072537 0.09762340196323627 FSTLTDDPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FSTLTDDPSPR 11 0 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-4 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 FSTLTDDPS(0.999)PR;FSTLT(0.002)DDPS(0.998)PR 97.163 0.013581999999999999 0.0 22178.1 26323.0 29957.0 27994.0 32148.0 30430.0 32674.0 27003.0 26971.0 23478.3 True False 25932.414292558165 28936.173477353488 30671.288492555144 26425.586937772536 25848.83017634895 28834.197231046594 29578.88218072532 26294.199862043482 27365.399850881015 27734.72993587945 0.9350159295768121 1.0433191000688191 1.1058801929373312 0.9527977016133363 0.9320022309973612 1.0396422571162232 1.0664925257649671 0.9480604254244998 0.9866834800319924 1.0 14.759406056984433 FSTLTDDPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 FSTLTDDPSPR 11 0 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-4 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 FSTLT(0.002)DDPS(0.998)PR;FSTLTDDPS(1)PR;FS(0.001)T(0.005)LT(0.192)DDPS(0.803)PR;FSTLT(0.001)DDPS(0.999)PR 100.04 0.008739499999999999 3976300.0 78061.0 88202.0 109709.0 77921.0 93326.0 88592.0 77292.0 85758.0 110364.0 64269.2 True False 76947.83582536576 87997.77368811466 100689.14950898656 83651.57027683608 87836.74816597553 84803.12667803868 81293.80156733944 89742.629754971 97933.64413555808 75378.0455866741 1.020825563020026 1.167419147090112 1.335788805948919 1.1097604033875965 1.1652829080713651 1.1250374829701186 1.0784811536916683 1.1905672143194488 1.299232997795734 1.0 16.201856768622207 FSTYSQS(ph)PPDTPSLR ddPTM_PC-9_AZD4547_30min_R2 1 FSTYSQSPPDTPSLR 15 0 H3BSV5;A0A0A0MTL6;Q6ZS17-2;Q6ZS17;Q6ZS17-3;Q6ZS17-4;H3BMG9 H3BSV5 FAM65A Protein FAM65A 1 FSTYS(0.001)QS(0.995)PPDT(0.004)PSLR 145.94 0.00011426 6261300.0 19348.0 18959.0 21284.0 31077.0 23638.0 25468.0 16258.0 23563.0 21803.0 20602.0 True False 25500.26153659955 25087.125986548013 21001.76025328144 23912.67778486375 20356.27172158042 23875.481933942738 17704.9305040807 19921.879773873854 22955.46206829332 19880.730250760767 1.282662216878263 1.2618815139141086 1.056387767872751 1.2028068125892253 1.023919718482245 1.2009358626567102 0.8905573528116852 1.002069819498281 1.1546588972713863 1.0 14.279083129900455 -1.5228787458797144 0.3289815657216181 1.0160646373385251 4.0232181562667755 0.45509296035111013 0.09157188837470408 51.112358532246205 0.7278698091334758 0.0818445055234385 93.35414422505956 0.029999999958596514 1.5228787458797144 3.0071535189282503 FSTYSQS(ph)PPDTPSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FSTYSQSPPDTPSLR 15 0 H3BSV5;A0A0A0MTL6;Q6ZS17-2;Q6ZS17;Q6ZS17-3;Q6ZS17-4;H3BMG9 H3BSV5 FAM65A Protein FAM65A 1 FSTYS(0.036)QS(0.963)PPDT(0.001)PSLR 163.9 0.00032069 23099000.0 27740.0 35949.0 26912.0 36928.0 39026.0 47620.0 45174.0 38572.0 34472.0 30661.0 True False 32435.834110025815 39517.77914133575 27553.68414432834 34859.04388219133 31379.135450485068 45122.72336978105 40894.7916885623 37559.525870412195 34976.08778538322 36219.596587657565 0.8955327271943959 1.091060720284281 0.7607396752099034 0.9624360060948368 0.866357950026921 1.2458096616448062 1.129079159940116 1.0369945943354664 0.9656675137376298 1.0 15.144482857250368 -6.731943160679836 24.999406062684525 1.0811705978843913 0.9190342823229739 0.3653968920124806 0.10542467360957969 234.567970730506 198806.61291086717 0.03506650726574781 0.035061381436516194 1.853774224636475e-07 6.731943160679836 -0.1621363155614174 FSTYSQS(ph)PPDTPSLR ddPTM_PC-9_Lapatinib_30min_R1 1 FSTYSQSPPDTPSLR 15 0 H3BSV5;A0A0A0MTL6;Q6ZS17-2;Q6ZS17;Q6ZS17-3;Q6ZS17-4;H3BMG9 H3BSV5 FAM65A Protein FAM65A 1 FSTYS(0.06)QS(0.883)PPDT(0.056)PSLR 128.82 1.6884e-05 7403900.0 24695.0 22156.0 18532.0 15224.0 23820.0 25634.0 18553.0 22826.0 21017.0 14548.0 True False 24342.844771491633 22104.69914326058 17008.370495588722 16343.623745775227 22418.954431921848 24537.69357577257 19513.5835594738 23886.57929040986 18649.84414117851 17062.602416008507 1.4266783095556774 1.2955057267537025 0.9968215915076997 0.9578623088844455 1.3139235085784975 1.4380979511513887 1.1436463842799107 1.3999376360079132 1.0930245976827555 1.0 14.05855008519361 -8.51447668473511 22.255572277039104 0.9999999518658125 1.2361325265286656 0.2081320345815043 0.16023862833402105 193.82069569463587 513393.3410829483 0.16506168516296385 0.04261874386319002 3.0586044444490746e-09 8.51447668473511 0.2361325746628531 FSTYSQSPPDT(ph)PSLR ddPTM_PC-9_AZD4547_30min_R2 1 FSTYSQSPPDTPSLR 15 0 H3BSV5;A0A0A0MTL6;Q6ZS17-2;Q6ZS17;Q6ZS17-3;Q6ZS17-4;H3BMG9 H3BSV5 FAM65A Protein FAM65A 1 FSTYSQS(0.003)PPDT(0.957)PS(0.04)LR 145.94 0.00027938 6449100.0 8866.9 11089.0 16972.0 16758.0 19447.0 11369.0 9759.9 16254.0 14066.0 12479.0 True False 11686.389757022662 14673.30239278605 16746.940190692192 12894.702008519067 16747.11972965457 10658.094632754624 10628.512192568403 13742.317779762567 14809.500043691854 12042.114008311986 0.9704599831023201 1.2184988767468823 1.3906976947015062 1.0708005255238895 1.3907126039576594 0.8850684045507249 0.882611822578008 1.141188147718667 1.2298089881452459 1.0 13.555801060815522 -6.768526634655937 24.999994869416575 1.027489533060543 1.2113059004416227 0.25481026661275974 0.15429131849792516 248.9075077146483 878005.2138890459 0.05538663786652509 0.04987209741699521 1.7040148113333827e-07 6.768526634655937 0.18381636738107976 FSTYSQSPPDT(ph)PSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FSTYSQSPPDTPSLR 15 0 H3BSV5;A0A0A0MTL6;Q6ZS17-2;Q6ZS17;Q6ZS17-3;Q6ZS17-4;H3BMG9 H3BSV5 FAM65A Protein FAM65A 1 FST(0.006)Y(0.011)S(0.001)QS(0.003)PPDT(0.855)PS(0.124)LR;FS(0.005)T(0.125)YS(0.272)QS(0.181)PPDT(0.414)PS(0.002)LR 139.21 0.00014418 32526900.0 21728.0 23380.0 28097.0 33800.0 32977.0 30905.0 34487.0 28563.0 31098.0 25466.0 True False 25406.12125243841 25701.011886962915 28766.93903846586 31906.295581078502 26515.39357737526 29284.287394856874 31220.141695741986 27813.251515000095 31552.749418364074 30082.784211254933 0.8445402218765764 0.8543428595730624 0.9562591958394339 1.060616442847113 0.8814142132314668 0.9734566850331853 1.037807587106965 0.9245570928436293 1.0488640013100643 1.0 14.876650476547889 -5.304371026799864 3.8893924219837417 0.9846430362980968 0.8465138636176327 0.5235148495943185 0.052462560594053124 0.16385736211509044 5.296481588121293 0.013535088349598722 0.03299803170769467 4.961682534825239e-06 5.304371026799864 -0.1381291726804641 FSTYSQSPPDTPS(ph)LR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FSTYSQSPPDTPSLR 15 0 H3BSV5;A0A0A0MTL6;Q6ZS17-2;Q6ZS17;Q6ZS17-3;Q6ZS17-4;H3BMG9 H3BSV5 FAM65A Protein FAM65A 1 FSTYS(0.007)QS(0.097)PPDT(0.211)PS(0.686)LR 133.87 6.7725e-06 7386600.0 12747.0 10281.0 12250.0 15592.0 12663.0 13951.0 13635.0 10169.0 13392.0 10839.0 True False 14904.815335273952 11301.62973523805 12542.0864583837 14718.430789946031 10181.776052106103 13219.385000668124 12343.394091148602 9902.074524946125 13587.832664825122 12804.024898523203 1.1640726610109178 0.8826622741526817 0.9795424921291964 1.1495159456963906 0.7952012068705406 1.0324398074384273 0.9640245304874618 0.7733563940576386 1.061215732749186 1.0 13.644309766992397 -6.255730012102112 24.998882218655748 0.9324266883462398 1.0278274807061945 0.16284078127314738 0.11535303775112057 978.1305254577967 4282810.8716407195 0.033446157835479634 0.04194608512752386 5.549706143816654e-07 6.255730012102112 0.09540079235995469 FSVCVLGDQQHCDEAK ddPTM_PC-9_AZD4547_30min_R2 2 FSVCVLGDQQHCDEAK 16 0 P62906 P62906 RPL10A 60S ribosomal protein L10a 0 ; 136.26 8.294099999999999e-06 12472600.0 68969.0 64504.0 73727.0 94012.0 93765.0 87145.0 64084.0 74702.0 71050.0 73373.0 False True 90899.7073556819 85353.65655552987 72749.33180763389 72338.98587092102 80747.34825171278 81695.80937385897 69787.35185284207 63158.522381187584 74805.55794855011 70804.2336030029 1.2838174037071524 1.2054880366914942 1.0274714957799995 1.0216759957677592 1.1404310751311937 1.1538266176557292 0.9856381222080243 0.8920161855760692 1.0565125013284165 1.0 16.11154800561269 -1.5228787452803376 0.4421769466772095 1.0069348197033003 7.088715525639141 0.5731381677145989 0.07264674945299182 69.0428074521472 0.8461070192628064 0.05170963354687686 377.18643135734413 0.029999999999999995 1.5228787452803376 6.081780705935841 FSVCVLGDQQHCDEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FSVCVLGDQQHCDEAK 16 0 P62906 P62906 RPL10A 60S ribosomal protein L10a 0 ; 130.47 3.4958e-05 4012100.0 60911.0 59578.0 65897.0 75269.0 73949.0 64596.0 76117.0 71098.0 72421.0 59444.0 False True 71222.02925291212 65492.510102714936 67468.23439576427 71051.92195539059 59459.22429733827 61208.472045241026 68906.64672064225 69231.75283455788 73480.02011792852 70220.726641555 1.014259359867754 0.9326663683932599 0.9608022819268027 1.0118368942275187 0.846747493811203 0.8716581979802424 0.9812864380110943 0.9859162122880701 1.0464149779168583 1.0 16.09960930480178 -7.723754423208418 2.625359979252936 1.017737357274043 0.9393183473718948 0.27449589984815737 0.05176567574712114 0.39072392493101266 5.412880589048507 0.033835790299756995 0.015609170315384769 1.8890592373364095e-08 7.723754423208418 -0.07841900990214812 FSVCVLGDQQHCDEAK ddPTM_PC-9_Lapatinib_30min_R1 1 FSVCVLGDQQHCDEAK 16 0 P62906 P62906 RPL10A 60S ribosomal protein L10a 0 95.236 0.0020901 8826900.0 104700.0 102830.0 96956.0 97334.0 109160.0 88634.0 107200.0 99256.0 92511.0 92827.0 False True 103206.95880037147 102591.90345285647 88984.65194098334 104492.2670567058 102739.42341681743 84843.33043594546 112750.29146637158 103867.79611184265 82091.4369959826 108872.02326579763 0.9479658382797241 0.9423164957850648 0.8173325825289228 0.9597715181759854 0.9436714808357312 0.7792941463833268 1.035622266255727 0.9540356925145244 0.7540177405867298 1.0 16.73227374822416 FSVPSGS(ph)SPGSQSDAEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FSVPSGSSPGSQSDAEPR 18 0 Q8TEP8;K7ELX0 Q8TEP8 CEP192 Centrosomal protein of 192 kDa 1 FSVPS(0.002)GS(0.611)S(0.383)PGS(0.004)QSDAEPR 209.19 1.9197999999999998e-20 5784300.0 28198.0 28617.0 32437.0 34984.0 40160.0 33804.0 41036.0 43072.0 35645.0 25860.0 True False 32971.364464113474 31457.906636835654 33210.421098007544 33023.95989965829 32290.93629097218 32031.258731459027 37148.77300508794 41941.405638556316 36166.24069128524 30548.213292352637 1.079322189765103 1.029778937831063 1.0871477418393356 1.0810439086440917 1.0570482791232771 1.0485476981882162 1.2160702378750141 1.372957732001165 1.183906906278509 1.0 14.898800381536415 -7.268490122712232 18.168180918748405 1.2243142933334217 1.0638037726991156 0.3216391233210779 0.08753945135218158 12.432896560843322 32031.62269054445 0.03414176397015255 0.023809831108113945 5.3890210164369505e-08 7.268490122712232 -0.16051052063430604 FSVPSGSS(ph)PGSQSDAEPR ddPTM_PC-9_AZD4547_30min_R2 1 FSVPSGSSPGSQSDAEPR 18 0 Q8TEP8;K7ELX0 Q8TEP8 CEP192 Centrosomal protein of 192 kDa 1 FSVPSGS(0.05)S(0.93)PGS(0.02)QSDAEPR 223.93 8.240299999999999e-35 5736300.0 20742.0 17072.0 27840.0 37646.0 33695.0 32314.0 24724.0 33909.0 27670.0 31105.0 True False 27337.52453959832 22590.190138844224 27470.823409667148 28967.296324902043 29017.03086803672 30293.40047170665 26924.38810326552 28669.143201302402 29132.579710575414 30016.023417625147 0.9107643660600945 0.752604361495116 0.9152052897698807 0.9650610915999186 0.966718024713366 1.0092409660740946 0.89700050298654 0.9551279595706915 0.9705675966880082 1.0 14.873445238064367 -5.485965117181149 5.723311417958942 0.9619564497108389 0.8308242546214678 0.579421718948728 0.045397329012908806 0.12376879538885306 11.12910436422581 0.011467790997209583 0.0233788361057911 3.2661406497563893e-06 5.485965117181149 -0.13113219508937113 FSVPSGSS(ph)PGSQSDAEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FSVPSGSSPGSQSDAEPR 18 0 Q8TEP8;K7ELX0 Q8TEP8 CEP192 Centrosomal protein of 192 kDa 1 FSVPSGS(0.008)S(0.988)PGS(0.004)QSDAEPR;FSVPS(0.069)GS(0.151)S(0.538)PGS(0.072)QS(0.17)DAEPR 178.52 1.3752999999999999e-08 13862400.0 37703.0 34140.0 47721.0 52254.0 60995.0 53315.0 60805.0 55002.0 54334.0 37081.0 True False 44085.37323180618 37529.193576600264 48858.84962290029 49326.377789753766 49043.46760627113 50519.06754430652 55045.11020992234 53558.25577943621 55128.5319601709 43803.49176696553 1.006435136868546 0.8567626018550183 1.115409928569833 1.1260832367467408 1.1196246150234381 1.153311425789246 1.2566374959960314 1.2226937538305391 1.2585419503416428 1.0 15.418758257460306 -5.419570291444217 4.015579926206918 1.1709667330859648 0.9329500699060812 0.5610823827597851 0.07990151041105292 0.15519944298325475 4.340192076271548 0.021525963388223844 0.04744657181404232 3.8056575727529124e-06 5.419570291444217 -0.23801666317988357 FSVPSGSS(ph)PGSQSDAEPR ddPTM_PC-9_Lapatinib_30min_R1 3 FSVPSGSSPGSQSDAEPR 18 0 Q8TEP8;K7ELX0 Q8TEP8 CEP192 Centrosomal protein of 192 kDa 1 FSVPS(0.091)GS(0.325)S(0.422)PGS(0.151)QS(0.012)DAEPR;FS(0.001)VPS(0.006)GS(0.313)S(0.678)PGS(0.002)QSDAEPR;FSVPS(0.003)GS(0.157)S(0.679)PGS(0.157)QS(0.005)DAEPR 174.87 2.4455e-08 22251000.0 147519.0 173278.0 204411.0 184065.0 211117.0 181897.0 172496.0 169318.0 209517.0 176335.0 True False 145415.3520083287 172876.78543716867 187605.11662927878 197601.75412283998 198699.51313199167 174117.68933261686 181426.9988505898 177185.13240574847 185918.98914817968 206814.26979838184 0.7031204962311863 0.8359035650958805 0.9071188212117588 0.9554551255843085 0.9607630717440289 0.8419036534682057 0.877246038329263 0.8567355268980323 0.8989659626941001 1.0 17.657976206787495 -4.822391560685767 2.2579176808646504 0.9064973765301331 0.6624235670335509 0.6536362170179042 0.04664007738561223 0.36538694844836783 2.3870065946233394 0.012888731792942825 0.17488864404502857 1.5052493187126708e-05 4.822391560685767 -0.2440738094965822 FSVPSGSSPGSQS(ph)DAEPR ddPTM_PC-9_AZD4547_30min_R2 1 FSVPSGSSPGSQSDAEPR 18 0 Q8TEP8;K7ELX0 Q8TEP8 CEP192 Centrosomal protein of 192 kDa 1 FSVPS(0.012)GS(0.108)S(0.239)PGS(0.036)QS(0.605)DAEPR 106.87 0.00030902 6375400.0 18251.0 16406.0 27935.0 32883.0 31285.0 28250.0 22835.0 27553.0 17896.0 26539.0 True False 24054.438355617043 21708.918663184075 27564.563647595256 25302.3323872856 26941.617768408654 26483.52303415589 24867.270762743414 23295.316954952526 18841.94602459188 25609.877687842913 0.939264085866203 0.8476775612829016 1.0763254703352307 0.9879911452797253 1.0520010324453022 1.0341136087005873 0.9710031053583666 0.9096223433355516 0.7357296373787919 1.0 14.644412742224626 -7.85753810869592 3.5928285593175944 0.8562765152862256 0.9899177691904446 0.24727883123904337 0.0848561656678837 0.2940934549882431 7.240667574430501 0.05182719964863789 0.022971866693141062 1.3882314893324782e-08 7.85753810869592 0.133641253904219 FSVS(ph)PVVR ddPTM_PC-9_AZD4547_30min_R2 1 FSVSPVVR 8 0 P13639 P13639 EEF2 Elongation factor 2 1 FS(0.029)VS(0.971)PVVR 71.61399999999999 0.03493 4269300.0 15703.0 18244.0 25608.0 29785.0 23380.0 19868.0 19958.0 25565.0 22378.0 24086.0 True False 20696.22735730943 24141.016219135086 25268.421188030043 22918.528423662738 20134.09056817626 18625.650819207392 21734.223336230923 21614.51667525718 23560.855394407532 23242.75647120781 0.8904377319853213 1.0386468682851797 1.087152516498271 0.9860503616278598 0.8662522705995548 0.801352922243973 0.9350966337901618 0.9299463556326623 1.0136859379649643 1.0 14.50449355463964 -4.412811073045079 10.285125216962179 0.9561738489488012 5.6079709372772386e-05 0.06369544722724607 0.07953984780426794 70169.93501134773 200877.75305612042 0.022389090341088963 1434364.8400469406 3.865350911310103e-05 4.412811073045079 -0.9561177692394284 FSVS(ph)PVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FSVSPVVR 8 0 P13639 P13639 EEF2 Elongation factor 2 1 FS(0.07)VS(0.93)PVVR 74.464 0.027748000000000002 2765400.0 22239.0 20933.0 16527.0 19690.0 28379.0 20568.0 18827.0 25610.0 21042.0 15772.0 True False 26003.623459728344 23011.089898622507 16921.066358996533 18586.8331358413 22818.33867035606 19489.377872105357 17043.570264323782 24937.76463603796 21349.69944244702 18631.338748916693 1.395692698746101 1.2350744199721275 0.9082045357572814 0.9976112498583615 1.2247288816904163 1.046053541012374 0.9147796888892253 1.3384848492161063 1.1459025961668152 1.0 14.185443721946614 -5.000217959496324 5.179727603185827 1.0792294310419341 1.3671759307477604 0.3922440075930673 0.12820327922240582 0.16913653826157887 14.620362681345846 0.03370875814729755 0.1214295456639908 9.994982556287144e-06 5.000217959496324 0.2879464997058263 FSVS(ph)PVVR ddPTM_PC-9_Lapatinib_30min_R1 1 FSVSPVVR 8 0 P13639 P13639 EEF2 Elongation factor 2 1 FS(0.033)VS(0.967)PVVR 86.882 0.012143000000000001 3288000.0 20965.0 14719.0 19889.0 15593.0 19318.0 18552.0 16171.0 15252.0 22108.0 15396.0 True False 20666.03525548988 14684.919059832664 18253.803193760214 16739.76123672313 18181.753220649287 17758.57420682426 17008.255254689306 15960.663600163449 19617.964232439183 18057.178086119537 1.1444775676978984 0.8132455132134344 1.0108890274384468 0.9270419307428165 1.0068989259526389 0.983463425022938 0.9419110324754159 0.8838957850469632 1.0864357730136922 1.0 14.140284830548833 -8.276452180873154 24.912661422352226 1.0432178761012678 0.9606306462577913 0.12176611217713784 0.08474225938986567 1713.3978329922131 2843229.8179283687 0.07370420664410052 0.01931933685156997 5.291122532872139e-09 8.276452180873154 -0.08258722984347655 FT(ph)GSHK ddPTM_PC-9_AZD4547_30min_R2 1 FTGSHK 6 0 O94811 O94811 TPPP Tubulin polymerization-promoting protein 1 FT(0.993)GS(0.007)HK 42.773 0.042006 3102100.0 16362.0 9755.0 31190.0 70957.0 43702.0 21796.0 13060.0 29313.0 21656.0 23812.0 True False 21564.77564925791 12908.112980577867 30776.40022081605 54598.95992472172 37634.731651430215 20433.09267442343 14222.314699427598 24783.349395729085 22800.691948399755 22978.349127808728 0.9384823743999916 0.5617511035619301 1.3393651584643218 2.3761045504633436 1.6378344432883616 0.8892324057212191 0.6189441469585624 1.0785522170405148 0.9922684968175556 1.0 14.487987531289878 -6.781510291966407 24.520962076724228 0.9021552642965053 1.379879620038071 0.20077894640428018 0.4532105027364961 366.6795633641619 447974.8322059121 0.18335275118313255 0.16192023782421452 1.65382559173566e-07 6.781510291966407 0.4777243557415657 FT(ph)SGAFLSPSVSVQECR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FTSGAFLSPSVSVQECR 17 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 FT(0.431)S(0.431)GAFLS(0.132)PS(0.004)VS(0.001)VQECR;FT(0.554)S(0.341)GAFLS(0.104)PS(0.001)VSVQECR 191.15 1.9666e-08 16164900.0 35403.0 30520.0 35610.0 39187.0 35208.0 28547.0 31793.0 30268.0 29962.0 24195.0 True False 41396.02865887687 33549.823900346775 36459.077451677054 36991.479435968155 28309.245142742737 27049.94506587863 28781.336878612958 29473.49707159691 30400.137567464935 28581.361972485367 1.4483574540194375 1.1738357301742455 1.2756242157660431 1.294251808978838 0.9904792210390607 0.9464190367106718 1.0069966891822755 1.0312138763705656 1.063635021897503 1.0 14.802787045602958 -6.260471972481812 24.98594279929566 1.0050430500985919 1.2875476959309173 0.8131608285156832 0.06839105778809905 36.67298732842997 947178.9134456619 0.020398681767725507 0.02482502842366649 5.48943980973021e-07 6.260471972481812 0.2825046458323255 FT(ph)Y(ph)FSS(ph)LSPMARK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FTYFSSLSPMARK 13 1 Q9H425 Q9H425 C1orf198 Uncharacterized protein C1orf198 3 FT(0.999)Y(0.999)FS(0.474)S(0.523)LS(0.005)PMARK 64.55 0.024179 0.0 10944.0 10178.0 5080.4 7515.4 7429.8 5068.4 9604.5 5770.0 4702.5 7744.2 True False 12796.603046147171 11188.404575941333 5201.536003524294 7094.336503255547 5973.984025265565 4802.604181591736 8694.692229441638 5618.54361382035 4771.265166244038 9148.162156946535 1.3988168144166795 1.223022109139765 0.5685880851570364 0.775493086102388 0.6530255938597787 0.5249802199827582 0.950430488689954 0.6141718431995637 0.5215545029031914 1.0 13.159266223318232 -5.154008038375984 4.310149398351579 0.6912856907780205 1.3582668818923076 0.7030745952285868 0.15964225197001253 0.1109313341724061 3.405332160425716 0.03943826175872365 0.11693247146274952 7.014423152726416e-06 5.154008038375984 0.6669811911142871 FT(ph)YFS(ph)SLS(ph)PMARK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FTYFSSLSPMARK 13 1 Q9H425 Q9H425 C1orf198 Uncharacterized protein C1orf198 3 FT(0.754)Y(0.278)FS(0.925)S(0.288)LS(0.754)PMARK 52.372 0.040583999999999995 0.0 3228.7 5926.6 4185.7 3483.5 3740.0 3201.3 4486.6 4115.3 2638.7 2192.1 True False 3775.2551402682193 6514.953680465118 4285.5029623556475 3288.330788659378 3007.1738478146412 3033.4181924334334 4061.5967678289185 4007.2777355207754 2677.2859955700474 2589.5103773459473 1.4579030743787058 2.5159017463148587 1.6549472054048937 1.269865847006054 1.1612905181313726 1.1714253856524253 1.568480591296857 1.5475040264669389 1.0338966080198 1.0 11.338463624677686 -5.563110116547952 4.368505085604669 1.2837341635089003 2.0117528181960282 0.4973223902816942 0.2982338732247238 0.15162948745039617 6.41590511572662 0.07871361273639595 0.14724864262885773 2.734575279392679e-06 5.563110116547952 0.7280186546871279 FTASAGIQVVGDDLTVTNPK ddPTM_PC-9_Lapatinib_30min_R1 1 FTASAGIQVVGDDLTVTNPK 20 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 74.783 0.045794999999999995 0.0 16110.0 14906.0 14704.0 13173.0 16576.0 15146.0 13630.0 9708.5 16528.0 12968.0 False True 15880.268445787815 14871.486072821906 13495.093879081409 14141.786363839798 15601.032269669884 14498.240887050457 14335.694707897805 10159.592352621741 14666.442592444131 15209.501521226153 1.0441018348711526 0.9777760337554444 0.8872804845213275 0.9297994641115445 1.025742510226079 0.9532357695495101 0.9425486225101541 0.6679766814476573 0.9642947582454207 1.0 13.892685250255534 -7.5470188026638105 24.99997476262038 0.8507339516776266 0.9654247000629604 0.14654558530202755 0.09278025699928741 326.85200577753176 338491.0042341353 0.041569013972321336 0.024001316751221108 2.8377961641535202e-08 7.5470188026638105 0.11469074838533388 FTAT(ph)MSTPDKK ddPTM_PC-9_AZD4547_30min_R2 1 FTATMSTPDKK 11 1 H0Y322;Q5TKA1;Q5TKA1-2;B1B047;C9J5J4;H7C4T7;Q5TKA1-3 H0Y322 LIN9 Protein lin-9 homolog 1 FT(0.111)AT(0.614)MS(0.164)T(0.111)PDKK 58.32 0.033527 24303000.0 35382.0 42108.0 51215.0 58490.0 59837.0 49165.0 54050.0 53418.0 48580.0 58549.0 True False 46632.74000868127 55718.58753318023 50535.855636713444 45006.03416149182 51529.665411803355 46090.70477785042 58860.34529127577 45163.47552352388 51147.83962196438 56499.21733092864 0.8253696637166283 0.9861833520068768 0.8944523132190232 0.796578010946264 0.9120421104239816 0.8157759869112308 1.0417904543087293 0.7993646223272658 0.9052840382262283 1.0 15.785943261933756 FTATMS(ph)TPDKK ddPTM_PC-9_AZD4547_30min_R2 1 FTATMSTPDKK 11 1 H0Y322;Q5TKA1;Q5TKA1-2;B1B047;C9J5J4;H7C4T7;Q5TKA1-3 H0Y322 LIN9 Protein lin-9 homolog 1 FT(0.149)AT(0.06)MS(0.45)T(0.341)PDKK 49.31 0.043542000000000004 32065000.0 92848.0 79209.0 93761.0 117560.0 120490.0 113540.0 102440.0 94884.0 99801.0 114820.0 True False 122371.73264162694 104811.760233582 92517.6678776508 90458.35828389427 103762.04330879221 106440.32585125894 111556.96154742422 80221.85801741041 105076.27711222028 110800.18674848827 1.1044361587531037 0.9459529203818063 0.8349955951578132 0.8164097998248948 0.9364789568841401 0.9606511412555104 1.0068300859515138 0.7240227690185274 0.9483402528078674 1.0 16.7576007874204 -4.803330399940424 3.51159316924637 0.8970312735544843 1.1242444313835174 0.3336563171288359 0.08448217942550876 0.3058607471716594 6.297060226068675 0.02145802156642088 0.17924103077515458 1.572785874638919e-05 4.803330399940424 0.22721315782903306 FTATMST(ph)PDKK ddPTM_PC-9_Lapatinib_30min_R1 1 FTATMSTPDKK 11 1 H0Y322;Q5TKA1;Q5TKA1-2;B1B047;C9J5J4;H7C4T7;Q5TKA1-3 H0Y322 LIN9 Protein lin-9 homolog 1 FT(0.001)AT(0.004)MS(0.325)T(0.67)PDKK 54.871 0.0403 17150000.0 91367.0 83239.0 67550.0 78049.0 70879.0 65889.0 71195.0 61912.0 71536.0 60976.0 True False 90064.08982534408 83046.26520968904 61996.299750540566 83788.98382383166 66710.03657347549 63071.08106476088 74881.12874018964 64788.65754086805 63478.86237252437 71515.62035458715 1.2593624914220183 1.16123253630369 0.8668917285923257 1.1716179403659086 0.9328037181627632 0.8819203518342322 1.0470597663687415 0.9059371535845508 0.8876223412141975 1.0 16.12597076755016 -1.5228787452874866 0.6008197787634963 0.945484118542147 22.018511714411623 0.5251341540686902 0.09277997342448324 131.91986999711744 1.0192317326886926 0.041001277496825396 3650.3768033522165 0.029999999999506165 1.5228787452874866 21.073027595869476 FTDEEVDELYR ddPTM_PC-9_AZD4547_30min_R2 3 FTDEEVDELYR 11 0 J3QRS3;P19105;O14950 J3QRS3 MYL12A;MYL12B Myosin regulatory light chain 12A;Myosin regulatory light chain 12B 0 ;; 217.66 3.862e-08 101203900.0 44896.1 46556.2 57295.1 63348.0 62943.0 59966.9 50773.8 71616.0 51325.1 60284.7 False True 59172.12590310767 61604.58119388816 56535.32953804667 48744.09731684361 54204.450925265926 56217.160263253885 55292.56983811614 60549.392771962426 54038.0400037316 58174.15100223461 1.0171549542826113 1.058968289739575 0.9718290437255374 0.837899590747293 0.9317617875194053 0.9663597885785122 0.9504662962076098 1.0408298484602994 0.9289012228413246 1.0 15.828090630537984 -5.386122880488839 5.367049730937511 0.9492440059232353 1.0368993316026576 0.3151864253349428 0.05037370259487855 0.2619545389007761 10.246135546615646 0.014029112365670275 0.029962335719433835 4.110334057147645e-06 5.386122880488839 0.08765532567942225 FTDEEVDELYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 FTDEEVDELYR 11 0 J3QRS3;P19105;O14950 J3QRS3 MYL12A;MYL12B Myosin regulatory light chain 12A;Myosin regulatory light chain 12B 0 ;;;; 242.12 1.1054e-19 96309400.0 62019.700000000004 70438.0 76432.9 70234.8 85997.9 56972.2 69655.0 54011.1 56531.4 49806.6 False True 72518.41026508904 77430.6191314753 78255.35020938724 66299.77186029375 69147.22883609054 53984.47753817388 63056.77414147086 52593.36585449085 57358.06477809847 58836.14231117137 1.232548692291129 1.3160383412284553 1.3300557639471324 1.1268545022827787 1.175250893751431 0.9175393800066275 1.0717353596702093 0.8938955510770259 0.9748780685644605 1.0 15.844415036560395 -6.3631034988168755 1.2321156304582117 0.9650271817249277 1.294190079281851 0.7943738439717333 0.06811359107075836 0.18441171068094522 0.5768955553132319 0.027260066687778847 0.0357788434104949 4.3340757862441603e-07 6.3631034988168755 0.3291628975569233 FTDEEVDELYR ddPTM_PC-9_Lapatinib_30min_R1 4 FTDEEVDELYR 11 0 J3QRS3;P19105;O14950 J3QRS3 MYL12A;MYL12B Myosin regulatory light chain 12A;Myosin regulatory light chain 12B 0 ;;; 217.66 3.862e-08 129540600.0 52176.5 65710.9 71292.3 62427.6 69379.0 69285.2 67469.9 67161.0 70752.7 55871.4 False True 51432.45354200179 65558.7504483156 65430.92229023627 67018.73395636863 65298.26362436204 66322.03350768969 70963.16128924384 70281.54524328478 62783.785867039056 65528.69704603913 0.78488442255866 1.000458629632989 0.9985079093555886 1.0227386927788695 0.9964834731642048 1.0121067028250719 1.0829325850838536 1.0725307905009374 0.9581113114904214 1.0 15.999839225425129 -4.748439012583084 3.805380572156686 1.0210906440444378 0.7517735523135132 0.7993872666881946 0.034791835721926574 0.13017075229224606 3.2178431732936494 0.009144116403862746 0.10330687452973451 1.784682591630704e-05 4.748439012583084 -0.26931709173092466 FTGSFDDDPDPHRDPYGEEVDRR ddPTM_PC-9_AZD4547_30min_R2 2 FTGSFDDDPDPHRDPYGEEVDRR 23 2 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0;X6RGP5 O15027 SEC16A Protein transport protein Sec16A 0 ; 40.723 0.026616 10246500.0 23457.0 20970.7 27718.0 40151.0 38106.0 30691.0 30894.0 35695.0 21046.7 32357.0 False True 30915.838064090112 27749.0686706104 27350.44120938053 30894.807276766234 32815.63965743904 28771.886918275322 33643.50615039175 30179.157939499528 22159.185594310373 31224.191278704293 0.9901245411975014 0.8887041596345838 0.8759375371888091 0.9894509997393365 1.0509684418894831 0.9214613970770316 1.0774820667120848 0.9665312920396595 0.7096800489248704 1.0 14.930376585383893 -12.130756343434447 2.1545132096395623 2.0921109961491355 0.946516414555332 0.02854705122427892 0.0986157869363302 4220382.468724798 739670.8229952789 22953198.075578064 0.026498649754674763 7.400203396067637e-13 12.130756343434447 -1.1455945815938036 FTGSFDDDPDPHRDPYGEEVDRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FTGSFDDDPDPHRDPYGEEVDRR 23 2 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0;X6RGP5 O15027 SEC16A Protein transport protein Sec16A 0 45.423 0.014765 2439200.0 10268.0 11721.0 13047.0 14498.0 14925.0 15781.0 17758.0 13590.0 12061.0 10865.0 False True 12006.169597755768 12884.583418609589 13358.089961023044 13685.724063150188 12000.55339000896 14953.416579137238 16075.83368321356 13233.276899795243 12237.369307829735 12834.73849270733 0.9354432585110828 1.0038835949739513 1.0407761691921562 1.0663033041870222 0.9350056798451831 1.1650737245354656 1.2525252222589351 1.0310515408875967 0.9534568479741897 1.0 13.647766280907444 -6.759936030111229 24.999513350789975 1.093118667001065 1.0030666235538166 0.17743528682984067 0.08788834518638661 73.07093066588031 1215123.8091360857 0.03182729953458011 0.030229918659152116 1.738056818908091e-07 6.759936030111229 -0.09005204344724849 FTGSFDDDPDPHRDPYGEEVDRR ddPTM_PC-9_Lapatinib_30min_R1 1 FTGSFDDDPDPHRDPYGEEVDRR 23 2 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0;X6RGP5 O15027 SEC16A Protein transport protein Sec16A 0 53.059 0.0042201999999999995 5499900.0 24734.0 20986.0 24630.0 18119.0 19489.0 15940.0 17042.0 17972.0 21620.0 12641.0 False True 24381.288624339904 20937.40820637599 22605.016474549433 19451.53170321213 18342.695336848217 15258.283357954857 17924.35137285358 18807.044730011643 19184.927931307007 14825.980006926275 1.644497605753526 1.41221074064545 1.5246895290556857 1.3119896083850735 1.2371995192411587 1.0291585008766113 1.208982567390475 1.2685194989623303 1.2940074060766544 1.0 13.855839850553666 -5.942723858198903 1.8921885508283862 1.1782144821568832 1.5289907128017117 0.7017154479591662 0.10334251960266833 0.20101812560655655 1.4578919119328122 0.03350865426223472 0.05686782163060535 1.1409750345261938e-06 5.942723858198903 0.35077623064482855 FTGVASGS(ph)TGSTGSCSVGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FTGVASGSTGSTGSCSVGAK 20 0 Q9UKI8-5;Q9UKI8;Q9UKI8-2;B3KRP1;F8W7X8 Q9UKI8-5 TLK1 Serine/threonine-protein kinase tousled-like 1 1 FTGVASGS(0.466)T(0.314)GS(0.213)T(0.006)GSCSVGAK 221.37 3.4819999999999994e-87 0.0 8958.3 12493.0 8352.8 10871.0 14299.0 9303.6 14367.0 10399.0 8237.3 8688.3 True False 10474.763255509892 13733.222476639332 8551.962430170399 10261.933114257528 11497.21359623036 8815.702837948242 13006.053751927546 10126.037268651267 8357.754929059443 10263.420013455041 1.0205918925443747 1.3380746825751535 0.8332468532866265 0.9998551263423339 1.1202127147829721 0.858943980309791 1.2672241548019074 0.9866143308347832 0.8143245543983071 1.0 13.325223930600792 -5.26077479684127 24.999841706303787 0.9955041260328584 1.179333272959606 0.21469594734642616 0.14754728298880412 89.45209770754362 3364754.311924894 0.037103302856654204 0.08703704212710396 5.485613473586918e-06 5.26077479684127 0.18382914692674757 FTGVASGST(ph)GSTGSCSVGAK ddPTM_PC-9_AZD4547_30min_R2 1 FTGVASGSTGSTGSCSVGAK 20 0 Q9UKI8-5;Q9UKI8;Q9UKI8-2;B3KRP1;F8W7X8 Q9UKI8-5 TLK1 Serine/threonine-protein kinase tousled-like 1 1 FTGVASGS(0.006)T(0.804)GS(0.148)T(0.042)GSCSVGAK 164.97 1.2390000000000002e-07 6165400.0 20681.0 18944.0 25625.0 33253.0 24785.0 24132.0 17822.0 30060.0 19491.0 18964.0 True False 27257.12780847714 25067.277529888986 25285.19575692243 25587.03460372862 21344.030570241594 22623.022225141583 19408.123474211236 25414.917710081405 20521.254468334846 18300.07613219236 1.4894543395110849 1.3697908876888323 1.3816989379865081 1.3981927954232658 1.1663356160958531 1.2362255797037132 1.0605487831861895 1.388787539816463 1.121375360413672 1.0 14.15956202998816 -1.5228787452803993 0.125333843348166 0.9455641957267419 2.675882436921245 0.6430968870326266 0.09467034724124433 59.21477256873115 0.5078817331697667 0.5772218374442865 17.992412215404595 0.02999999999999573 1.5228787452803993 1.730318241194503 FTGVASGSTGS(ph)TGSCSVGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FTGVASGSTGSTGSCSVGAK 20 0 Q9UKI8-5;Q9UKI8;Q9UKI8-2;B3KRP1;F8W7X8 Q9UKI8-5 TLK1 Serine/threonine-protein kinase tousled-like 1 1 FTGVASGST(0.043)GS(0.599)T(0.358)GSCSVGAK 221.9 2.9400999999999995e-87 0.0 9403.1 9815.2 10137.0 11689.0 13108.0 9851.8 13905.0 12554.0 9346.3 8799.7 True False 10994.859110309442 10789.588189603004 10378.704524786583 11034.10322624931 10539.581496565332 9335.154264897288 12587.817736517876 12224.470802062502 9482.97195603756 10395.015951613135 1.0577048810207186 1.0379578290044507 0.9984308415780717 1.061480162956075 1.0139071979903755 0.8980413602394354 1.2109474189469094 1.1759934625367714 0.912261414525868 1.0 13.343604351626974 -7.259016702885532 24.99997198087314 1.089466690384969 1.0142883167966112 0.09875841034008859 0.08949174964619275 460.762896534397 4754715.280930652 0.035344135384878135 0.02608729729653896 5.507865128505296e-08 7.259016702885532 -0.07517837358835777 FTGVASGSTGS(ph)TGSCSVGAK ddPTM_PC-9_Lapatinib_30min_R1 1 FTGVASGSTGSTGSCSVGAK 20 0 Q9UKI8-5;Q9UKI8;Q9UKI8-2;B3KRP1;F8W7X8 Q9UKI8-5 TLK1 Serine/threonine-protein kinase tousled-like 1 1 FTGVAS(0.002)GS(0.043)T(0.043)GS(0.777)T(0.125)GS(0.008)CS(0.002)VGAK 215.51 2.1291e-28 4193600.0 14235.0 10508.0 12988.0 10159.0 11349.0 9983.0 10840.0 9611.5 13019.0 10460.0 True False 14032.006289620713 10483.6693716096 11920.17677512985 10906.126749430541 10681.47413299248 9556.050361509622 11401.24215947265 10058.08537850584 11552.663123852262 12267.997062926099 1.1437895051365354 0.8545542779180524 0.971648160167289 0.8889900032980012 0.87067791736533 0.7789413636548722 0.9293482954872248 0.819863693063751 0.9416910571950187 1.0 13.582612105872297 -4.756817529385183 24.99553093437404 0.8883316719598048 1.1437898904576036 0.567892080207621 0.06484455180064294 97.53630982731784 527423.975317264 0.01542201481370467 0.1209471121262112 1.7505820483874285e-05 4.756817529385183 0.2554582184977988 FTGVASGSTGST(ph)GSCSVGAK ddPTM_PC-9_Lapatinib_30min_R1 1 FTGVASGSTGSTGSCSVGAK 20 0 Q9UKI8-5;Q9UKI8;Q9UKI8-2;B3KRP1;F8W7X8 Q9UKI8-5 TLK1 Serine/threonine-protein kinase tousled-like 1 1 FTGVAS(0.062)GS(0.113)T(0.014)GS(0.28)T(0.523)GS(0.009)CS(0.001)VGAK 126.14 4.2368000000000005e-05 4057500.0 28074.0 31352.0 30043.0 25944.0 23255.0 26196.0 27041.0 24843.0 27863.0 18604.0 True False 27673.659611858922 31279.406370261127 27572.98050933368 27852.008306646894 21887.186621089106 25075.658145858575 28441.050667370822 25997.29647383036 24724.775529602524 21819.67661172823 1.2682891733136015 1.4335412447610807 1.263675030569106 1.2764629284962108 1.003093996788412 1.1492222635591323 1.303458853834871 1.1914611264154404 1.1331412453799972 1.0 14.413342099262605 -1.5228787452803398 0.11146407734445915 0.954042880142074 2.1680604517036217 0.446303550596457 0.09577138040952125 111.02699914670181 0.8653411969903204 0.9224724291742485 20.750230488813884 0.029999999999999843 1.5228787452803398 1.2140175715615478 FTIGDHSR ddPTM_PC-9_AZD4547_30min_R2 2 FTIGDHSR 8 0 O75083;D6RD66 O75083 WDR1 WD repeat-containing protein 1 0 ; 129.42 0.0031769000000000003 3787900.0 19818.6 13865.9 30245.0 40119.0 31307.0 33107.0 27173.0 32788.0 26155.0 34034.0 False True 26120.50254751148 18347.781012546868 29843.93153826807 30870.184382371193 26960.5634481563 31036.81405634687 29591.3443589239 27721.36799328506 27537.499903509233 32842.48001914338 0.7953267394023301 0.558660034256007 0.9086990848703416 0.9399468117017178 0.8209052249538219 0.9450204137524323 0.9010082168482878 0.8440704836275061 0.8384719999055504 1.0 15.003275452348099 -5.279647851155433 24.86743450617315 0.8944756498473786 0.6769933880294796 0.5896715404909711 0.07422805510874461 424.6968255841229 580011.0227791928 0.018216889452497942 0.03804081007358868 5.252331743577958e-06 5.279647851155433 -0.21748226181789898 FTIGDHSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FTIGDHSR 8 0 O75083;D6RD66 O75083 WDR1 WD repeat-containing protein 1 0 ; 127.68 0.0030488000000000004 3471900.0 21457.0 24419.0 31428.0 35613.0 42377.0 34709.0 35092.0 30453.0 33636.0 26961.0 False True 25089.24630493237 26843.156940451136 32177.36271135374 33617.71906890383 34073.53105583987 32888.798938297594 31767.831715921282 29653.64101762062 34127.86286693983 31848.815876841443 0.7877607256091355 0.8428306108538834 1.0103158257369058 1.055540626656347 1.0698523671210052 1.0326537434069052 0.9974572316524004 0.9310751499299218 1.0715582958848895 1.0 14.958952114342935 -5.204042967276604 3.2738607734230567 1.0224502847220789 0.7979549031493003 0.8161668988176614 0.0394652484403499 0.10403033884386266 2.200281030970261 0.011173765602064737 0.035007627715374474 6.251108438681506e-06 5.204042967276604 -0.2244953815727786 FTIGDHSR ddPTM_PC-9_Lapatinib_30min_R1 2 FTIGDHSR 8 0 O75083;D6RD66 O75083 WDR1 WD repeat-containing protein 1 0 ; 138.06 0.002568 4160600.0 47962.0 42478.0 58851.0 51943.0 54097.0 54391.0 49188.0 41580.0 51446.0 43204.0 False True 47278.0530848464 42379.64480084054 54012.497951429505 55763.06149676843 50915.120818794116 52064.823721613735 51734.71396126759 43511.95859525283 45651.609729603144 50671.75383428867 0.9330257886762582 0.8363563838629756 1.065929119565627 1.1004762471638503 1.0048028135221316 1.0274920400797811 1.020977369965427 0.8587024387896569 0.9009281557314386 1.0 15.628894143366333 -9.901312488913758 8.165936394585144 1.0000001647263554 0.9753178672064885 0.00862607820910899 0.08353634943648863 0.0 0.0 0.08889720235950856 0.021560738538244785 1.2551265346101463e-10 9.901312488913758 -0.024682297519866947 FTPPSTALS(ph)PGK ddPTM_PC-9_AZD4547_30min_R2 2 FTPPSTALSPGK 12 0 C9JWM1;A8MZI9;H9KVB1;Q01196-6;Q01196-5;Q01196-7;Q01196-3;Q01196-4;Q01196;Q01196-9;Q01196-10;Q01196-2;Q01196-8 C9JWM1 RUNX1 Runt-related transcription factor 1 1 FTPPS(0.066)T(0.012)ALS(0.923)PGK;FTPPS(0.009)T(0.019)ALS(0.973)PGK 122.46 0.00039983 41406000.0 237730.0 265800.0 242480.0 217592.0 255590.0 278830.0 309280.0 292740.0 275110.0 265350.0 True False 313323.1949088184 351714.65199770354 239264.5567663823 167429.52616288819 220105.74030454076 261394.71602172308 336805.32084524946 247503.75949598206 289651.7529518033 256060.17726625438 1.2236310942760196 1.3735624795416217 0.9344075260777165 0.6538678835201812 0.8595859873816779 1.0208331448193984 1.3153365917381028 0.9665843480168521 1.1311862549037448 1.0 17.966123375448106 -5.26458071285718 24.949064004343832 0.9807718930682615 1.2985967983173112 0.3661912662099438 0.16482583858944924 285.2915494306295 2265861.288020944 0.04780421414937744 0.10673547134367099 5.437750627005122e-06 5.26458071285718 0.3178249052490497 FTPPSTALS(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FTPPSTALSPGK 12 0 C9JWM1;A8MZI9;H9KVB1;Q01196-6;Q01196-5;Q01196-7;Q01196-3;Q01196-4;Q01196;Q01196-9;Q01196-10;Q01196-2;Q01196-8 C9JWM1 RUNX1 Runt-related transcription factor 1 1 FTPPSTALS(1)PGK;FTPPS(0.007)T(0.082)ALS(0.91)PGK;FTPPS(0.001)T(0.001)ALS(0.998)PGK 115.37 0.00072576 25806200.0 123669.0 145963.0 134027.0 140183.0 138198.0 112519.0 151779.0 120815.0 110823.0 96101.0 True False 144603.71912591177 160453.24200413853 137222.7119802282 132329.00098941795 111119.09396264383 106618.30556162108 137401.39433519958 117643.73426407395 112443.57671848252 113523.35056490255 1.2737795211852934 1.4133941713815579 1.2087619973987331 1.1656544695953457 0.9788214795432402 0.9391751127065812 1.2103359674593617 1.0362954729460327 0.9904885308524901 1.0 16.792629549744554 -5.76162115646213 1.8909848483485847 1.0346013920272656 1.3396140558047684 0.7058729988138502 0.08019087806119125 0.18776975394768314 1.3691076807247335 0.025303272816785263 0.05117560605306557 1.7313259700627925e-06 5.76162115646213 0.3050126637775028 FTPPSTALS(ph)PGK ddPTM_PC-9_Lapatinib_30min_R1 2 FTPPSTALSPGK 12 0 C9JWM1;A8MZI9;H9KVB1;Q01196-6;Q01196-5;Q01196-7;Q01196-3;Q01196-4;Q01196;Q01196-9;Q01196-10;Q01196-2;Q01196-8 C9JWM1 RUNX1 Runt-related transcription factor 1 1 FT(0.002)PPS(0.306)T(0.044)ALS(0.648)PGK;FTPPS(0.015)T(0.009)ALS(0.976)PGK 75.102 0.020111 28952000.0 126037.0 187081.0 157655.0 175120.0 194533.0 171884.0 181643.0 190164.0 161312.0 164690.0 True False 124239.6892676451 186647.82543872253 144693.2144658987 187998.90898319494 183090.95140659335 164532.92200117387 191047.58575397515 198999.71366781282 143143.34386933353 193156.44706436887 0.6432075716646546 0.9663038861784543 0.7490985502424368 0.9732986490507605 0.9478894139400834 0.8518117023882911 0.9890821075742248 1.0302514707236083 0.7410746368803905 1.0 17.55941030625241 -4.754821017851665 24.92757858862732 0.9152457274408083 0.6432070942402006 0.41471859578863624 0.09740043972011642 213.04779608562185 802353.1302543695 0.02321862175563912 0.21752793070551388 1.7586482416051426e-05 4.754821017851665 -0.2720386332006077 FTPVASKFS(ph)PGAPGGSGSQPNQK ddPTM_PC-9_AZD4547_30min_R2 2 FTPVASKFSPGAPGGSGSQPNQK 23 1 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 FTPVAS(0.006)KFS(0.994)PGAPGGSGSQPNQK;FTPVAS(0.013)KFS(0.678)PGAPGGS(0.209)GS(0.1)QPNQK 102.15 1.9787000000000002e-06 273120000.0 218951.0 150160.0 250180.0 384620.0 329781.0 238862.0 192853.0 247929.0 184664.0 265565.0 True False 288572.86353628384 198696.28346115572 246862.44973529177 295951.80131976417 283996.60058442 223925.921379984 210016.54339423517 209617.26989164203 194424.96204097214 256267.65018169474 1.126060442399517 0.7753467256607663 0.9632993066439145 1.1548543138782177 1.1082030852628701 0.8737970681091417 0.8195203071684336 0.8179622739858995 0.7586793022963456 1.0 17.967291846675124 -6.909662318903211 6.484158301017443 0.8356489875762471 1.0148238713232947 0.3510924925919404 0.11589670375282977 0.2556795351920209 15.192462532071938 0.04294522425020665 0.03783593470641215 1.231225725314396e-07 6.909662318903211 0.1791748837470476 FTPVASKFS(ph)PGAPGGSGSQPNQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FTPVASKFSPGAPGGSGSQPNQK 23 1 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 FTPVAS(0.005)KFS(0.991)PGAPGGS(0.002)GS(0.002)QPNQK;FT(0.008)PVAS(0.104)KFS(0.88)PGAPGGS(0.006)GS(0.001)QPNQK 76.0 0.00017225 155236000.0 177956.0 96131.0 144242.0 202714.0 210935.0 222783.0 200930.0 227496.0 196742.0 142132.0 True False 208080.4360087867 105674.25037235356 147681.276320831 191356.5917876553 169603.80095956713 211099.8672929428 181896.45579277497 221524.47105193677 199618.97955070424 167899.40648370725 1.2393160903101736 0.6293902556624467 0.8795818842585474 1.139709757140948 1.010151283506921 1.257299663613925 1.0833656866465813 1.3193880531878666 1.188920102407122 1.0 17.357237604863478 -5.7719346367024675 7.387839816653738 1.1532900760517848 0.8868145389125272 0.27232845714728493 0.16711234295592242 0.15011867119261588 45.276746814584236 0.04503842058620121 0.070717801849549 1.6906953698492098e-06 5.7719346367024675 -0.26647553713925765 FTPVASKFS(ph)PGAPGGSGSQPNQK ddPTM_PC-9_Lapatinib_30min_R1 2 FTPVASKFSPGAPGGSGSQPNQK 23 1 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 FT(0.035)PVAS(0.177)KFS(0.787)PGAPGGS(0.001)GSQPNQK;FT(0.007)PVAS(0.014)KFS(0.741)PGAPGGS(0.013)GS(0.225)QPNQK 80.191 9.059899999999999e-05 186214000.0 218553.0 126077.0 171362.0 150833.0 140034.0 136834.0 100523.0 88854.0 160497.0 105424.0 True False 215436.3941422879 125785.0764526476 157273.2778364487 161925.76198413796 131797.47543743663 130981.92879563331 105727.58907718353 92982.4812174746 142420.13775166433 123646.39793134978 1.742358837350856 1.0172967313005368 1.2719600446732708 1.3095873773374411 1.065922482518354 1.0593266846993499 0.8550802194487297 0.7520031539382148 1.1518341022011656 1.0 16.915860686164073 -1.5228787453140156 0.3859973181401762 0.9372917080707711 10.399409858895021 0.5642652577703312 0.1726987185593463 54.58460604884067 0.7392380560472327 0.13295347045818048 388.3004966008897 0.029999999997673606 1.5228787453140156 9.46211815082425 FTQAGSEVSALLGR ddPTM_PC-9_Lapatinib_30min_R1 1 FTQAGSEVSALLGR 14 0 P06576;H0YH81;F8W0P7 P06576 ATP5B ATP synthase subunit beta, mitochondrial;ATP synthase subunit beta 0 96.866 0.018516 0.0 10969.0 8828.2 6637.6 6916.3 11203.0 10562.0 11347.0 11038.0 11872.0 9214.5 False True 10812.580048531756 8807.75884530299 6091.882149876955 7424.947774100444 10544.061565945434 10110.287881224542 11934.492138702599 11550.865776200118 10534.850342297712 10807.214047450534 1.0004965202926177 0.8149888404755687 0.5636866377523128 0.6870362464831553 0.9756502942988181 0.935512874718124 1.1043079267517601 1.0688106782640263 0.9747979725434351 1.0 13.39970704342307 -6.375828120130757 4.523359893719514 1.019699052637248 0.7563556976178814 0.5329159939199609 0.11168151139949593 0.19096053648844516 6.278977098818656 0.038458055886057926 0.043809127297056924 4.2089317148514343e-07 6.375828120130757 -0.2633433550193667 FTS(ph)GAFLSPSVSVQECR ddPTM_PC-9_AZD4547_30min_R2 2 FTSGAFLSPSVSVQECR 17 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 FT(0.107)S(0.442)GAFLS(0.342)PS(0.104)VS(0.006)VQECR;FT(0.116)S(0.721)GAFLS(0.159)PS(0.005)VSVQECR 199.84 1.6719e-12 14879500.0 16668.1 20670.1 25149.1 27165.7 32341.0 26118.4 17525.4 26576.0 20022.9 22639.8 True False 21968.20908198237 27351.305599163785 24815.60650186998 20903.067570881147 27851.010396295485 24485.212319125574 19085.12664880157 22469.289855725994 21081.269616439484 21847.187493018813 1.0055394585230812 1.2519371478779038 1.135871906157244 0.95678528769713 1.274809876795133 1.1207489443183354 0.8735736192542016 1.0284751693052467 0.9649420376501975 1.0 14.41515994526888 -7.17909113834077 8.637125314320986 0.9693176373955653 1.130273847216527 0.384352569491602 0.0975022988933845 0.3759712366511952 36.62476876601174 0.036605588265383265 0.028334779124574147 6.620775496425933e-08 7.17909113834077 0.1609562098209617 FTS(ph)PADLDASGAGPGPK ddPTM_PC-9_AZD4547_30min_R2 1 FTSPADLDASGAGPGPK 17 0 P52735-3;P52735-2;P52735 P52735-3 VAV2 Guanine nucleotide exchange factor VAV2 1 FT(0.036)S(0.964)PADLDASGAGPGPK 163.9 5.4314e-18 0.0 53482.0 48592.0 66632.0 62696.0 54394.0 80875.0 52272.0 63386.0 52751.0 56543.0 True False 70488.16350529337 64298.41373164937 65748.41614342465 48242.40584354406 46842.3320087844 75817.87346503911 56924.10673571816 53591.15016537652 55539.310166699084 54563.44678034973 1.2918568687394343 1.1784155423774576 1.204990154087975 0.8841524626871243 0.8584929063838762 1.389535997794477 1.0432644947243066 0.982180439976835 1.0178849292691823 1.0 15.735647162032002 -5.624708821110897 9.375064937705812 1.0334593886372647 1.2242619738724954 0.3057177331465777 0.13801173796631203 0.3911930773489477 32.58274135082315 0.039467065887997504 0.0684309054930094 2.372964159875366e-06 5.624708821110897 0.19080258523523064 FTSGAFLS(ph)PSVSVQECR ddPTM_PC-9_AZD4547_30min_R2 1 FTSGAFLSPSVSVQECR 17 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 FTSGAFLS(0.997)PS(0.003)VSVQECR 176.21 4.9319e-06 13416000.0 11426.0 12677.0 17489.0 17055.0 14126.0 13210.0 11031.0 17603.0 11581.0 15019.0 True False 15059.230324435937 16774.592337753522 17257.084432890406 13123.23324712332 12164.848732508888 12383.976611723869 12012.737630121419 14882.860826698696 12193.148016919904 14493.189381427816 1.0390556507688689 1.1574120710275955 1.190703024622335 0.9054758688201497 0.8393493255595927 0.8544686946265408 0.8288539750619037 1.0268865213180904 0.8413019174747498 1.0 13.823087489865209 -5.772190175054727 24.79426691710051 0.8932735903605081 1.1318924220492488 0.674037278979283 0.07306506434222279 100.68958230141394 232217.8371334693 0.020391187698928764 0.030596759628653075 1.6897008593344975e-06 5.772190175054727 0.23861883168874065 FTSGAFLS(ph)PSVSVQECR ddPTM_PC-9_Lapatinib_30min_R1 2 FTSGAFLSPSVSVQECR 17 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 FT(0.064)S(0.046)GAFLS(0.835)PS(0.051)VS(0.004)VQECR;FT(0.001)S(0.007)GAFLS(0.968)PS(0.024)VSVQECR 249.89 1.1062999999999999e-47 21148100.0 48311.0 47047.0 53993.0 41529.0 51065.0 53626.0 45637.0 46544.0 47934.0 39187.0 True False 47622.076280847636 46938.06556205905 49553.90395900723 44583.18119668283 48061.45709765274 51332.54098831165 47999.860556444 48706.60415722581 42535.168152602644 45960.4207366047 1.0361540542408378 1.0212714507349083 1.078186473596412 0.9700342268880716 1.045714036716263 1.1168857935938865 1.044373828332146 1.0597510505040686 0.9254738636177443 1.0 15.488104384492457 -8.251186122516911 24.947215526517407 0.9627369302736103 1.0464526204554285 0.4202050846281249 0.03937839742283045 577.1233614216357 1404208.9578665977 0.02751069350371102 0.010144242587750244 5.608075831817709e-09 8.251186122516911 0.08371569018181824 FTSGAFLSPSVSVQECRT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 FTSGAFLSPSVSVQECRTPR 20 1 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 FTSGAFLSPSVSVQECRT(1)PR;FTSGAFLSPS(0.005)VS(0.104)VQECRT(0.891)PR 130.01 2.4368e-05 24024500.0 25782.0 19920.7 38519.0 54150.0 43501.0 35835.0 30769.0 39776.0 24206.0 39253.0 True False 33980.13970108587 26359.67670447949 38008.212892132506 41666.554109160235 37461.6370319177 33594.231785096505 33507.38139254882 33629.533161550135 25485.47974247157 37878.764417683335 0.8970762437336148 0.6958958960174987 1.0034174418421298 1.0999977097908877 0.9889878301951448 0.8868882684413371 0.8845954166579474 0.887820225356942 0.6728170819260916 1.0 15.20910165128622 -7.511052525232487 1.8533637229278 0.8345686694523837 0.932896325346167 0.0717733336308608 0.1227850916306032 0.949636964805002 6.398692897503397 0.08049827248873477 0.040762802142477704 3.082815080277716e-08 7.511052525232487 0.09832765589378323 FTSGAFLSPSVSVQECRT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FTSGAFLSPSVSVQECRTPR 20 1 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 FTSGAFLSPS(0.062)VS(0.194)VQECRT(0.744)PR 63.46 0.0058911 8097900.0 30000.0 25239.0 30579.0 36389.0 40000.0 46089.0 40305.0 49291.0 47700.0 36746.0 True False 35078.407472991144 27744.561121259918 31308.1193315033 34350.24230472976 32162.287142402565 43672.011704952514 36487.01861706965 47997.1634781315 48397.52226046584 43407.758918824045 0.8081137646057828 0.6391613345702654 0.7212562940660441 0.7913387643201631 0.7409340621004783 1.0060876855361882 0.8405644411475669 1.1057277471497666 1.1149509549887855 1.0 15.405665319759224 -7.02067011019148 0.9098850327009838 1.0750750749638935 0.7147598484317831 0.7317748206953933 0.08245543977251682 0.28189137062294284 0.4818167914523944 0.055366066642068626 0.03957171628171582 9.535201823228035e-08 7.02067011019148 -0.36031522653211046 FTSGAFLSPSVSVQECRT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 FTSGAFLSPSVSVQECRTPR 20 1 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 FTSGAFLSPS(0.001)VS(0.001)VQECRT(0.998)PR 85.881 0.00055098 5811200.0 22745.0 24123.0 27431.0 25303.0 33408.0 34806.0 28901.0 29955.0 35334.0 25039.0 True False 22420.652129077844 24067.14467561271 25175.729066722113 27163.86702833359 31443.007122655126 33317.42851674887 30397.352366320934 31346.818656103875 31354.3128364848 29366.95778762968 0.7634652622588696 0.8195314220034933 0.8572808000332589 0.9249806270289221 1.0706933741669336 1.1345209387260147 1.0350868682463694 1.0674179764479443 1.0676731673477007 1.0 14.841906199790822 -5.9376910239912 1.7629949589812917 1.069474091329556 0.7981601931562997 0.9027209360827801 0.037066754846858334 0.09973011884898181 0.628708154275112 0.01230002852497564 0.021469228500350747 1.1542741666843842e-06 5.9376910239912 -0.27131389817325624 FTSQQGPIKPVS(ph)PNSSPFGTDYR ddPTM_PC-9_AZD4547_30min_R2 1 FTSQQGPIKPVSPNSSPFGTDYR 23 1 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 FT(0.001)SQQGPIKPVS(0.948)PNS(0.016)S(0.016)PFGT(0.016)DY(0.004)R 60.993 0.0021961 9246100.0 17114.0 14509.0 18320.0 24092.0 25153.0 22494.0 18527.0 24090.0 17669.0 18095.0 True False 22555.896006686224 19198.750511040933 18077.064829924657 18537.961617689536 21660.94012238398 21087.446624081513 20175.867108445258 20367.44403312911 18602.947268021577 17461.49955768935 1.2917502263861127 1.099490364364873 1.0352527152780666 1.0616477443099184 1.2404971320372864 1.207653818872357 1.1554487082732028 1.1664200984479651 1.0653693977748653 1.0 14.091889839521667 -8.470630795104732 3.1498141919459908 1.0007703941782602 1.1524069660487406 0.3246227442836134 0.07440865312526161 0.29549770940273384 6.334587645213821 0.0762316410504825 0.020314601919077403 3.3835235600415196e-09 8.470630795104732 0.1516365718704804 FTSQQGPIKPVS(ph)PNSSPFGTDYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FTSQQGPIKPVSPNSSPFGTDYR 23 1 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 FT(0.002)S(0.006)QQGPIKPVS(0.981)PNS(0.003)S(0.003)PFGT(0.004)DYR 54.828 0.0047024 5724100.0 26488.0 25646.0 24404.0 31275.0 39089.0 34436.0 33667.0 32572.0 35304.0 29570.0 True False 30971.895238153007 28191.965391490616 24985.88391268538 29522.76314491805 31429.791052734374 32630.115538886617 30477.818032027884 31717.0195128867 35820.25421139386 34930.80692400879 0.886664178858842 0.8070802788158207 0.7152964993634882 0.8451783896416758 0.8997728315039843 0.934135750424338 0.8725197244464381 0.9079956149277165 1.0254631188257415 1.0 15.092212349846484 -7.251558576526576 0.5396917852582459 1.0051720202397638 0.8001200112583595 0.606874479269067 0.05340042117009507 0.6589012093890002 0.40534151315298567 0.05413489698333017 0.04527461174742542 5.6032683681967135e-08 7.251558576526576 -0.2050520089814043 FTSQQGPIKPVSPNSSPFGT(ph)DYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FTSQQGPIKPVSPNSSPFGTDYR 23 1 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 FTSQQGPIKPVS(0.112)PNS(0.227)S(0.227)PFGT(0.432)DY(0.003)R 59.99100000000001 0.0039777 5078400.0 23748.0 20927.0 18111.0 25435.0 32268.0 25659.0 26742.0 26566.0 22250.0 24182.0 True False 27768.067355619787 23004.49425827514 18542.834926349977 24009.95941138259 25945.317037776156 24313.39686991205 24208.804164686167 25868.67064900369 22575.364157135547 28566.005175393322 0.9720668740737722 0.8053101620975391 0.6491224381042514 0.8405081236932879 0.9082585009165153 0.8511304510599033 0.8474690113666844 0.9055753680002442 0.790287757021829 1.0 14.802011675655132 -5.9965693172205 24.999560803009842 0.8755047696653891 0.7978699453261027 0.12040371171594133 0.08868140068891249 216.65292339007036 1578723.7092863286 0.025043251761377117 0.03693027347950281 1.0079307219135037e-06 5.9965693172205 -0.07763482433928648 FTVHS(ph)PDASSGTNSNGITNPCIR ddPTM_PC-9_AZD4547_30min_R2 1 FTVHSPDASSGTNSNGITNPCIR 23 0 A0A087WV86;Q6PGQ7-2;Q6PGQ7 A0A087WV86 BORA Protein aurora borealis 1 FT(0.006)VHS(0.962)PDAS(0.028)S(0.003)GTNSNGITNPCIR 78.419 0.00015028 5423400.0 2992.9 2436.7 8919.3 11431.0 9676.0 6744.0 9145.3 10168.0 7259.3 11126.0 True False 3944.5799438127374 3224.3156227344 8801.024254232909 8795.759557189485 8332.654419917595 6322.296613888401 9959.213983206368 8596.769237395461 7643.011777845328 10736.482126490831 0.3673996656763406 0.30031397479616095 0.8197307228330927 0.8192403669622033 0.7761065795804649 0.5888610942954007 0.9276049515914846 0.8007063334259259 0.7118730034474905 1.0 13.390233742515377 -5.262063429257373 24.999999882378106 0.7944603118715586 0.3338567842878167 0.7586168706340668 0.10627536779471057 23.761287984632567 951947.8458483634 0.026734441162695088 0.061606921089842274 5.469360763558972e-06 5.262063429257373 -0.46060352758374196 FTVQMPT(ph)SQSPAVK ddPTM_PC-9_Lapatinib_30min_R1 1 FTVQMPTSQSPAVK 14 0 Q16594 Q16594 TAF9 Transcription initiation factor TFIID subunit 9 1 FTVQMPT(0.542)S(0.295)QS(0.163)PAVK 104.94 0.0028307 0.0 10997.0 10896.0 13020.0 12916.0 10780.0 11198.0 11243.0 9871.5 8540.1 6400.7 True False 10840.180763397193 10870.770981448251 11949.545858653422 13865.885726512923 10145.94159429544 10719.08764381295 11825.107527578495 10330.165927682503 7578.224006760175 7507.052466603353 1.4439996005918352 1.448074464619647 1.5917759882208633 1.8470479310219463 1.351521338026039 1.4278690193653218 1.575199797814773 1.3760615066483608 1.0094806237832281 1.0 12.874030850654043 -8.162743991838308 2.80516638164974 0.9865413626415052 1.5272538658894834 0.7199646369955709 0.1282408415136835 0.15309890452983016 2.1627842847339918 0.11693625700076163 0.03617216511253478 6.8747357291180575e-09 8.162743991838308 0.5407125032479783 FTVS(ph)WY(ph)Y(ph)RMNR ddPTM_PC-9_Lapatinib_30min_R1 1 FTVSWYYRMNR 11 1 Q9P2B2 Q9P2B2 PTGFRN Prostaglandin F2 receptor negative regulator 3 FT(0.219)VS(0.908)WY(0.89)Y(0.983)RMNR 48.44 0.035356 4322300.0 11574.0 11997.0 10181.0 11502.0 14355.0 16231.0 17845.0 13536.0 15232.0 10989.0 True False 11408.952637588345 11969.221683593478 9343.957479796498 12347.89544954721 13510.667123015877 15536.837966308996 18768.92678374441 14164.931975597461 13516.411759929142 12888.434008077907 0.8852086010168273 0.928679285326029 0.7249878048752947 0.9580601834022728 1.0482784110581613 1.2054868695895238 1.4562612317354355 1.0990421308530967 1.0487241313768334 1.0 13.653789361167709 -6.344854460710415 2.2422349477650276 1.1831242743649806 0.8569706907151385 0.5287604193268701 0.12805626097273407 0.2411396253179798 2.378740652720433 0.045771950292669415 0.05539244294296316 4.5200739417733165e-07 6.344854460710415 -0.32615358364984204 FVADGIFK ddPTM_PC-9_Lapatinib_30min_R1 2 FVADGIFK 8 0 P23396;P23396-2;E9PL09;F2Z2S8;H0YCJ7;E9PPU1;E9PQ96;E9PJH4;E9PK82;E9PQX2 P23396 RPS3 40S ribosomal protein S3 0 ; 111.82 0.017231 12318500.0 151566.0 146937.0 119833.0 102306.0 109820.0 100877.0 107454.0 96672.0 119722.0 106497.0 False True 149404.6410461999 146596.77640428225 109980.79330875668 109829.92452281114 103360.60351442712 96562.72586577247 113017.44234353997 101163.73403848665 106237.64763144929 124904.86455166711 1.196147496596487 1.1736674702820902 0.8805164931207538 0.8793086235434794 0.827514635922541 0.7730901931832218 0.9048281886314372 0.8099262939166001 0.8505485195694993 1.0 16.930470139756594 -5.26725933451181 4.00150571199427 0.8537125927087892 1.1946114895606734 0.8280550833730566 0.05814335471848097 0.07040307946969203 2.6839719270223292 0.014590310609382366 0.037677974789724365 5.4043151341840324e-06 5.26725933451181 0.34089889685188424 FVAFSGEGQS(ph)LR ddPTM_PC-9_AZD4547_30min_R2 2 FVAFSGEGQSLR 12 0 Q92890;Q92890-1 Q92890 UFD1L Ubiquitin fusion degradation protein 1 homolog 1 FVAFSGEGQS(1)LR;FVAFS(0.002)GEGQS(0.998)LR 102.33 0.0024411999999999997 16141400.0 20629.7 17759.0 31754.0 36041.0 49354.0 32953.0 29861.0 45370.0 33117.0 31424.0 True False 27189.5154755834 23499.24945382701 31332.921212304962 27732.30427789926 42502.049012051786 30892.443700691652 32518.571151577893 38359.10899888201 34867.49701030452 30323.855324721182 0.8966378181278768 0.7749426714442049 1.0332763059570842 0.9145375474500042 1.4016043988114686 1.0187505305602396 1.072375883717777 1.264981269304836 1.149837203644722 1.0 14.888165566576458 -5.802356230907706 1.842410352160728 1.1502614349089515 0.854851330289752 0.43063261069441716 0.13102525912780538 0.30441095203557367 2.109561894059961 0.039786598927556836 0.0780111094433017 1.5763177615091108e-06 5.802356230907706 -0.2954101046191995 FVAFSGEGQS(ph)LR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FVAFSGEGQSLR 12 0 Q92890;Q92890-1 Q92890 UFD1L Ubiquitin fusion degradation protein 1 homolog 1 FVAFS(0.011)GEGQS(0.989)LR;FVAFSGEGQS(1)LR;FVAFSGEGQS(1)LR 109.95 0.0012506 19181600.0 52633.8 43678.2 53531.4 47987.6 58498.4 41936.6 29287.5 54473.1 30454.3 21957.6 True False 61543.66277506405 48014.28303683245 54807.79159496503 45299.01034989834 47036.058454278085 39737.370870834944 26513.175976862112 53043.23884402032 30899.63652362485 25938.339063734034 2.3726909662119415 1.8510931991001742 2.1130031287005235 1.7464113734727769 1.8133797364088764 1.5319936551525064 1.0221616700944354 2.0449743799587883 1.191272750645299 1.0 14.662798480525629 -1.5228787452803487 0.13253714759986904 0.8486650541889791 5.635323971606821 0.6137426063196284 0.27840156141075056 56.83338262449339 0.5096429559678453 1.3920603475095048 50.98392380453636 0.02999999999999923 1.5228787452803487 4.786658917417842 FVAFSGEGQS(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 3 FVAFSGEGQSLR 12 0 Q92890;Q92890-1 Q92890 UFD1L Ubiquitin fusion degradation protein 1 homolog 1 FVAFSGEGQS(1)LR;FVAFSGEGQS(1)LR;FVAFSGEGQS(1)LR 134.06 5.6244e-05 23068000.0 70367.0 39123.8 72729.0 78414.0 49566.0 35917.8 30847.3 34579.2 60614.0 48183.4 True False 69363.55367627267 39033.21124485912 66749.50236205863 84180.82714143567 46650.625330505354 34381.679422481255 32444.422257001912 36185.87586957592 53787.01302628321 56511.83648965519 1.2274163783187273 0.6907085961010022 1.1811596739433075 1.4896140768110668 0.8255018457778313 0.6083978429682606 0.574117287144633 0.6403238350995716 0.9517831372570812 1.0 15.786265453386276 -6.503870854921714 23.76376762488058 0.7206781202565655 1.1221050901227756 0.4034020242537866 0.2253259178728082 408.8155216628518 511104.0440938743 0.07250130303642498 0.08079561864564153 3.134217600306739e-07 6.503870854921714 0.40142696986621007 FVAFSGEGQS(ph)LRK ddPTM_PC-9_AZD4547_30min_R2 1 FVAFSGEGQSLRK 13 1 Q92890;Q92890-1 Q92890 UFD1L Ubiquitin fusion degradation protein 1 homolog 1 FVAFS(0.009)GEGQS(0.991)LRK 62.94 0.021748 4942400.0 15351.0 15336.0 14439.0 25147.0 28520.0 21371.0 23808.0 31484.0 21991.0 21192.0 True False 20232.298679364252 20293.062088174505 14247.529425725004 19349.74766727706 24560.49029103451 20034.667991608698 25926.865877792658 26618.871230346078 23153.39936448371 20450.074530342772 0.9893508529440617 0.9923221579493365 0.6966981662871327 0.9461944815197078 1.200997593167346 0.9796867958540828 1.2678127817736655 1.3016515509931448 1.1321914416561114 1.0 14.319818480631387 -6.176249631544205 4.875074543885407 1.1596461993553053 0.8916900851681029 0.480312787733986 0.12284171032840964 0.19155347381182125 7.889653449956351 0.03784127205530004 0.04923599164072493 6.664236002342649e-07 6.176249631544205 -0.26795611418720244 FVAFSGEGQS(ph)LRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FVAFSGEGQSLRK 13 1 Q92890;Q92890-1 Q92890 UFD1L Ubiquitin fusion degradation protein 1 homolog 1 FVAFS(0.027)GEGQS(0.973)LRK 57.148 0.032339 6611100.0 18451.0 17250.0 23236.0 22300.0 26162.0 21667.0 19420.0 20894.0 20535.0 13662.0 True False 21574.389876138677 18962.465998721553 23790.034363020724 21050.603297575475 21035.743905488405 20530.74437742644 17580.397011375575 20345.554639022936 20835.285526596774 16138.812451667505 1.336801573272484 1.1749604288116193 1.4740882846409604 1.3043464852583049 1.3034257612501678 1.2721347644947165 1.0893240790811174 1.2606599587146685 1.2910048734375135 1.0 13.978246803696576 -7.042872519746015 6.310678379729474 1.1811471181088313 1.3159433861529541 0.34111308477370406 0.10260649787127588 0.2856030343659239 30.444002667728917 0.038438527160607784 0.030286337663778123 9.059985033552749e-08 7.042872519746015 0.1347962680441228 FVAFSGEGQS(ph)LRK ddPTM_PC-9_Lapatinib_30min_R1 1 FVAFSGEGQSLRK 13 1 Q92890;Q92890-1 Q92890 UFD1L Ubiquitin fusion degradation protein 1 homolog 1 FVAFS(0.018)GEGQS(0.982)LRK 52.42 0.042532 4143000.0 20875.0 10501.0 18016.0 17321.0 10277.0 11031.0 7184.9 9309.9 10896.0 8535.1 True False 20577.31867199384 10476.685579679523 16534.79402377112 18594.84412116216 9672.527065359389 10559.229844516938 7556.898966014297 9742.47194146091 9668.777740033356 10010.380662694124 2.055598020231111 1.0465821363540335 1.6517647610936166 1.857556145737786 0.9662496753401376 1.054828003081663 0.7549062538827056 0.9732369097379449 0.9658751316087483 1.0 13.28920921583516 -6.277311668772418 23.44657827322063 0.9464128262556055 1.6094892582237688 0.6491745700771977 0.2513948941791719 231.31357637965027 341695.8575239177 0.07638555030785274 0.08696088747592128 5.2806615232544e-07 6.277311668772418 0.6630764319681632 FVCVGGS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 3 FVCVGGSPSR 10 0 F8WD51;C9J486;C9JIP2;B4DND0;Q16831 F8WD51 UPP1 Uridine phosphorylase 1 1 FVCVGGS(0.966)PS(0.034)R;FVCVGGS(0.665)PS(0.335)R;FVCVGGS(0.998)PS(0.002)R 112.85 0.0013925 27788900.0 85403.0 88391.0 138892.0 183290.0 157198.0 149666.0 118343.0 149359.0 118340.0 127540.0 True False 112559.37750724697 116961.66216978552 137050.2013295795 141035.32230227123 135373.7711349946 140307.36136035295 128875.29773923103 126278.99847837827 124595.21080410181 123074.86342015465 0.9145602471480324 0.9503294086177467 1.113551520765988 1.1459311705331976 1.0999302974877476 1.1400163888979487 1.0471293175380156 1.026034033020092 1.0123530292189475 1.0 16.909176613008782 -5.168207459683304 4.955847917531943 1.0788854240671366 0.9246791110882941 0.5624943037607657 0.04965839435483159 0.16263286326481002 6.461981057257845 0.01381964547501684 0.03913196685804538 6.788792588881201e-06 5.168207459683304 -0.15420631297884246 FVCVGGS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FVCVGGSPSR 10 0 F8WD51;C9J486;C9JIP2;B4DND0;Q16831 F8WD51 UPP1 Uridine phosphorylase 1 1 FVCVGGS(0.629)PS(0.371)R;FVCVGGS(0.974)PS(0.026)R 108.43 0.0020288 11660200.0 71639.0 80361.0 62428.0 88417.0 98063.0 72827.0 90682.0 75671.0 67468.0 73847.0 True False 83766.06776525399 88338.70899265284 63916.52027950843 83463.28214178153 78848.25910113579 69007.82391539372 82091.94447917411 73684.71643005176 68454.59186308408 87234.87652746984 0.9602359870237962 1.0126535682644706 0.7326945692343754 0.9567650630593757 0.9038616461651878 0.7910577358777311 0.9410450011163111 0.8446703814253558 0.7847158681026855 1.0 16.412617419754284 -5.206290524963333 24.9999932288269 0.8679222132845431 0.9864449283294371 0.25216979819210483 0.08062792993526807 393.64132827674274 178443.17907246764 0.019340731476180636 0.051170733849598395 6.218841313454638e-06 5.206290524963333 0.11852271504489398 FVCVGGS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 4 FVCVGGSPSR 10 0 F8WD51;C9J486;C9JIP2;B4DND0;Q16831 F8WD51 UPP1 Uridine phosphorylase 1 1 FVCVGGS(0.702)PS(0.298)R;FVCVGGS(0.71)PS(0.29)R;FVCVGGS(0.816)PS(0.184)R;FVCVGGS(0.796)PS(0.204)R 101.3 0.003657 30170900.0 131929.0 125181.0 164728.0 117349.0 131598.0 135819.0 115444.0 114736.0 145737.0 106106.0 True False 130047.66826718472 124891.15108559749 151184.69970846816 125979.23692478817 123857.66437162262 130010.33797955267 121421.1254481698 120067.05342436115 129322.56438135458 124446.28072264235 1.045010485745463 1.0035747983818548 1.2148591250020453 1.012318216287736 0.9952701169725466 1.044710514646164 0.9756910752422179 0.9648102998912331 1.0391838440682704 1.0 16.92516358813719 -5.965462803617652 24.999993261178403 1.0023542938092742 1.085090475999467 0.32424623880209336 0.05515232158781001 215.64678102265796 156096.03657661515 0.015482293583886449 0.0229638351198065 1.0827724482725882e-06 5.965462803617652 0.08273618219019285 FVCVGGSPS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 FVCVGGSPSR 10 0 F8WD51;C9J486;C9JIP2;B4DND0;Q16831 F8WD51 UPP1 Uridine phosphorylase 1 1 FVCVGGS(0.091)PS(0.909)R 90.913 0.008406700000000001 7594500.0 18050.0 14368.0 22603.0 32543.0 24354.0 24602.0 21427.0 33106.0 20329.0 21818.0 True False 23789.524536676763 19012.175018446203 22303.269451462173 25040.714134337966 20972.867480640067 23063.63305084259 23333.961490400852 27990.22840019809 21403.549437523936 21054.15846088235 1.1299204658726492 0.9030128206629556 1.0593284691430727 1.1893476616917484 0.9961389584678334 1.0954431208302031 1.1082827904878871 1.3294394288996465 1.0165948678162908 1.0 14.361817591386306 -7.170777252682822 3.165045000611456 1.141861274923527 1.0546767122937362 0.03329690238692995 0.11073081182633172 0.6005998700748794 11.580385715026276 0.04572528184533043 0.03359968593631108 6.74874078252131e-08 7.170777252682822 -0.08718456262979091 FVCVGGSPS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FVCVGGSPSR 10 0 F8WD51;C9J486;C9JIP2;B4DND0;Q16831 F8WD51 UPP1 Uridine phosphorylase 1 1 FVCVGGS(0.397)PS(0.603)R 95.48299999999999 0.0058993000000000006 2729100.0 13216.0 16587.0 16695.0 14331.0 22422.0 15232.0 15461.0 16870.0 13062.0 11160.0 True False 15453.207772101714 18233.647740335924 17093.072116140083 13528.08053172888 18028.57005767377 14433.207105596492 13996.42215205344 16427.180375242508 13253.007039123793 13183.219657488615 1.1721876881057391 1.3830951932882691 1.296577965036827 1.026159078222168 1.3675392298749112 1.094816553208065 1.061684665483283 1.2460674100890967 1.0052936523435332 1.0 13.686415133555348 -7.159987865012768 0.28471425023666486 0.9815848570483034 1.3329990309362652 0.33946779409820094 0.11497506551057467 2.5527049098482535 0.5505609194008605 0.18809393318462572 0.32195671160622163 6.918503022197946e-08 7.159987865012768 0.3514141738879617 FVDGEWYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FVDGEWYR 8 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 110.81 0.017306000000000002 4984100.0 22142.0 26726.0 26234.0 30782.0 35765.0 26944.0 28118.0 23603.0 22506.0 21568.0 False True 25890.203275565662 29379.180654019267 26859.51805299902 29057.38433659051 28757.104991200697 25531.009207798834 25454.459483308878 22983.446259445693 22835.107672831113 25478.107667805947 1.016174498245034 1.153114706832906 1.054219504964987 1.1404843999975447 1.1286986210336993 1.002076352792077 0.9990718233549601 0.9020860795123925 0.8962638815474306 1.0 14.636970508020656 -7.1472356975402285 1.786859414001865 0.930649451717366 1.1005653900667052 0.6592824986520562 0.05047006351471911 0.20145291294500448 1.266914497985816 0.024393157456902733 0.016593530934910037 7.124662600241102e-08 7.1472356975402285 0.16991593834933916 FVDGEWYR ddPTM_PC-9_Lapatinib_30min_R1 1 FVDGEWYR 8 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 116.88 0.016452 4889300.0 24727.0 18783.0 23202.0 19622.0 22776.0 20489.0 17447.0 17193.0 23746.0 14109.0 False True 24374.388445623572 18739.50911752409 21294.42112231004 21065.06733707314 21436.36045933888 19612.733232191797 18350.32029117336 17991.84954613233 21071.4754235345 16547.72185093923 1.4729754745206882 1.1324525083469696 1.2868491091479999 1.2729889665070429 1.2954266848594738 1.1852225586616687 1.1089333297037391 1.0872704840099263 1.2733762153693988 1.0 14.014344992317131 -6.932872163250988 3.342577962585577 1.1258237719152622 1.2819729248983667 0.4061499404692872 0.09938394692702575 0.2707593801368238 6.127642862979389 0.03606227906956213 0.030707487824005977 1.1671531238511599e-07 6.932872163250988 0.1561491529831045 FVDKYSISLS(ph)PPEQQK ddPTM_PC-9_AZD4547_30min_R2 2 FVDKYSISLSPPEQQK 16 1 A0A0U1RQT1;A0A087X1H5;Q15057;H7C3K3 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 FVDKYS(0.001)IS(0.013)LS(0.986)PPEQQK;FVDKYSIS(0.001)LS(0.999)PPEQQK 98.882 0.00093879 17353800.0 59796.0 48703.0 78775.0 99303.0 82807.0 76105.0 64246.0 78503.0 63827.0 73836.0 True False 78809.88416593475 64445.292310926045 77730.39202932939 76410.22756605619 71310.67740286447 71346.142319095 69963.76953900648 66372.16516947848 67200.76491459698 71251.02411392929 1.1060877390326203 0.9044823300768142 1.0909371899699252 1.0724088322418694 1.000837227109042 1.0013349731649277 0.9819335288028349 0.9315257709608554 0.9431550739136604 1.0 16.12062313018393 -7.058009925055356 1.5247184882988962 0.9550021901206258 1.0346315943647484 0.2761974014124695 0.05515748572107847 0.5387014936985152 2.5133041728585215 0.028153326665625745 0.019955862821463378 8.749637792027674e-08 7.058009925055356 0.07962940424412257 FVDKYSISLS(ph)PPEQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FVDKYSISLSPPEQQK 16 1 A0A0U1RQT1;A0A087X1H5;Q15057;H7C3K3 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 FVDKYSIS(0.145)LS(0.854)PPEQQK;FVDKYSISLS(1)PPEQQK 105.99 0.0005048 14673500.0 69953.0 45464.0 69595.0 84567.0 93052.0 82266.0 84276.0 89845.0 77165.0 66482.0 True False 81794.66126527169 49977.36545889141 71254.4087405071 79828.98515991315 74819.12857937124 77951.82613898382 76292.76717459786 87486.6639486463 78293.39214316232 78534.66032877771 1.0415103461687656 0.6363733573133955 0.9072988721439357 1.0164809375340376 0.9526892745973338 0.9925786374149462 0.9714534557761582 1.1139879332563722 0.9969278763719694 1.0 16.26104189022154 -5.5677096562659765 5.1103756182812194 1.0052502967622212 0.8233223356889887 0.31774924150207595 0.09952404347537536 0.18279472156954857 10.917725688044216 0.02572189602183398 0.046623080699138994 2.705766675951522e-06 5.5677096562659765 -0.1819279610732325 FVDKYSISLS(ph)PPEQQK ddPTM_PC-9_Lapatinib_30min_R1 1 FVDKYSISLSPPEQQK 16 1 A0A0U1RQT1;A0A087X1H5;Q15057;H7C3K3 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 FVDKY(0.016)S(0.005)IS(0.051)LS(0.928)PPEQQK 50.358000000000004 0.044614999999999995 5467900.0 18457.0 17092.0 17436.0 17307.0 19769.0 19484.0 13688.0 14006.0 20527.0 16578.0 True False 18193.799795400748 17052.424524129357 16002.479384906377 18579.81451445953 18606.226287349415 18650.714739422372 14396.697664101623 14656.769891416825 18215.03310110726 19443.485211203533 0.9357272936292973 0.8770250980674791 0.8230252555588947 0.9555804585771306 0.9569388453376825 0.9592269357489285 0.7404381214436854 0.7538139244178017 0.9368193460816157 1.0 14.246999222271642 -7.232725079448301 24.93089391686812 0.8372522857426554 0.9152336932610176 0.09229792288664462 0.08271652749407532 1269.0923396625167 1101877.561189364 0.03183863514948853 0.02465778856037437 5.851603898154295e-08 7.232725079448301 0.07798140751836213 FVEEACRLIMEEVVLKAT(ph)DVNEK ddPTM_PC-9_Lapatinib_30min_R1 1 FVEEACRLIMEEVVLKATDVNEK 23 2 Q6ZQY3-3;Q6ZQY3 Q6ZQY3-3 GADL1 Acidic amino acid decarboxylase GADL1 1 FVEEACRLIMEEVVLKAT(1)DVNEK 46.702 0.025488 50141000.0 52283.0 20415.0 25496.0 22913.0 20889.0 28293.0 11334.0 17322.0 20830.0 11473.0 True False 51537.434832472034 20367.730321793868 23399.817297406105 24598.09845552732 19660.35008935412 27082.97434420431 11920.819062312077 18126.84335706998 18483.90605037581 13456.092763188439 3.83004455598448 1.5136437211189162 1.7389756231036482 1.8280268194062872 1.461074208936679 2.0126923038383517 0.8859049407658381 1.3471104633478168 1.373645855128307 1.0 13.715971935895055 -4.761339773856671 8.27052992079569 1.4908448863589618 3.854994411092029 0.82217928617841 0.33011382479574025 0.03651640216324669 24.759052425510017 0.0827953770913781 0.4818867321152084 1.732448072428027e-05 4.761339773856671 2.364149524733067 FVEGLPINDFSR ddPTM_PC-9_Lapatinib_30min_R1 2 FVEGLPINDFSR 12 0 A0A5K1VW95;P40925;P40925-3;B9A041;P40925-2;B8ZZ51 A0A5K1VW95 MDH1 Malate dehydrogenase, cytoplasmic 0 ; 169.21 0.00038297 18733000.0 46383.0 42898.0 38736.0 34157.0 39698.0 48995.0 42109.0 33066.0 41983.0 34007.0 False True 45721.56991439956 42798.67231664527 35551.27560528411 36669.01972441174 37363.04168927091 46899.59806292338 44289.19797908061 34602.36707336774 37254.43243941082 39885.06463852083 1.1463331030994959 1.0730500929240188 0.8913430610552109 0.9193671881127391 0.9367677356898612 1.1758686738501094 1.1104206143446056 0.8675519868644996 0.9340446800587767 1.0 15.283560995528061 -5.026877620271921 6.235970411404345 0.982404322376172 1.1304728024391628 0.2591505138373178 0.09180819517881818 0.2288923758355449 32.63992570662798 0.025877146054401085 0.07841251180102479 9.399881522627845e-06 5.026877620271921 0.14806848006299078 FVEKMTIFT(ph)KT(ph)AREQY(ph)EK ddPTM_PC-9_AZD4547_30min_R2 1 FVEKMTIFTKTAREQYEK 18 3 A6NML8;K4DI95;C9J6U3 A6NML8 DIAPH2 3 FVEKMT(0.132)IFT(0.899)KT(0.97)AREQY(0.999)EK 42.708 0.028295999999999998 26409000.0 11727.0 11997.0 14941.0 19299.0 15279.0 16350.0 13467.0 13635.0 15014.0 11378.0 True False 15455.942063247 15874.795635878281 14742.872577724022 14849.91371657772 13157.774584737597 15327.631915343309 14665.536910964112 11528.024051129732 15807.609388311499 10979.659683193662 1.4076886268984357 1.445836764884207 1.342744037894966 1.3524930776596087 1.1983772689127998 1.3960024588744766 1.3357004983872447 1.049943657978347 1.4397176091448334 1.0 13.422545717956526 -14.364763323212946 0.08748854234109306 8.808210915202744e-17 1.600381986243618 0.47603437518086045 0.10982952194180964 181.1903996735349 1.1375060514630815 34.63127496721283 2.7606908350517485 4.317543051968371e-15 14.364763323212946 1.600381986243618 FVFDRPLPVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FVFDRPLPVSR 11 1 P25786;P25786-2;F5GX11;B4DEV8 P25786 PSMA1 Proteasome subunit alpha type-1;Proteasome subunit alpha type 0 ; 84.81700000000001 0.015297999999999999 7352600.0 26950.0 28718.0 36301.0 34610.0 38117.0 33843.0 35454.0 33252.0 33959.0 24435.0 False True 31512.102713237076 31568.9332493499 37166.55351230915 32670.913907133927 30648.247475173986 32068.21350280345 32095.540455268256 32379.170233406254 34455.586130883836 28864.872072646416 1.0917111509771522 1.0936799986467276 1.2876049967853402 1.1318572216398035 1.06178358934137 1.1109771566662392 1.1119238766931296 1.1217499995120415 1.193685738296946 1.0 14.817027210972833 -5.997711487114664 24.999891544053554 1.106302398797805 1.161010870585172 0.12278857535345156 0.06824369963043478 168.18043862917042 1837141.617497236 0.019415554229165667 0.028602883730214468 1.0052834038661496e-06 5.997711487114664 0.05470847178736715 FVFDRPLPVSR ddPTM_PC-9_Lapatinib_30min_R1 1 FVFDRPLPVSR 11 1 P25786;P25786-2;F5GX11;B4DEV8 P25786 PSMA1 Proteasome subunit alpha type-1;Proteasome subunit alpha type 0 84.81700000000001 0.030826999999999997 0.0 27706.0 25786.0 25851.0 23838.0 23589.0 27615.0 23464.0 25830.0 27048.0 23134.0 False True 27310.90735934188 25726.29410128711 23725.630567745735 25591.12604123684 22201.541397758356 26433.970823709136 24678.851109766252 27030.156097051018 24001.56941193301 27132.681075882654 1.0065686941500833 0.9481663101901995 0.8744300093821051 0.9431845665994264 0.818258296541604 0.9742483888628839 0.9095618321221661 0.9962213472916701 0.8845999901302498 1.0 14.727743991996716 FVGQDVEGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FVGQDVEGER 10 0 B4E1E0;P17812-2;P17812;A0A3B3IRI2 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 0 90.82700000000001 0.031287 0.0 10660.0 8008.3 13293.0 13217.0 18218.0 16119.0 13228.0 13205.0 13214.0 10999.0 False True 12464.527455402858 8803.311098989092 13609.955533983233 12476.494340092147 14648.313679007264 15273.691264122244 11974.948077573436 12858.38274185402 13407.22975156805 12993.031631963906 0.959324029100269 0.6775409579802943 1.0474811360038287 0.9602450523863088 1.1273976769956622 1.1755294450717515 0.921643879332526 0.9896368381203169 1.0318784815843274 1.0 13.665450470081645 -5.285121952804819 24.851536793637695 1.0334246742399316 0.8184324882276225 0.44758701315752636 0.09476830408497179 550.1639920858137 577319.1925082856 0.024750874481470182 0.05157027146041138 5.1865437684906275e-06 5.285121952804819 -0.21499218601230907 FVGQDVEGER ddPTM_PC-9_Lapatinib_30min_R1 2 FVGQDVEGER 10 0 B4E1E0;P17812-2;P17812;A0A3B3IRI2 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 0 ; 109.83 0.0084189 10000900.0 50226.0 46092.0 51979.0 37882.0 49188.0 45804.0 42856.0 41845.0 55003.0 38468.0 False True 49509.76802967963 45985.27680588406 47705.487264742405 40667.96865064748 46294.85854732879 43845.069694339065 45074.87398398154 43789.271462682904 48807.98293273261 45117.142544612 1.0973604540829285 1.019241782885821 1.057369429315499 0.9013861773368037 1.0261035149012876 0.9718051104629443 0.9990631374629131 0.9705683692043199 1.0818057212836805 1.0 15.461388078330913 -4.603453902473804 1.3210856600879461 0.9951153975869037 1.1714819009496233 0.2786109709839769 0.04678792429010457 2.4925644603798762 2.867789399815306 0.013133176145429356 0.6626627303127338 2.4919888655784233e-05 4.603453902473804 0.17636650336271964 FVHGEGLR ddPTM_PC-9_AZD4547_30min_R2 1 FVHGEGLR 8 0 B1AH87;P30536 B1AH87 TSPO Translocator protein 0 110.31 0.0031590999999999998 1572300.0 8640.0 8261.6 11864.0 13074.0 12146.0 8141.7 13967.0 12215.0 10777.0 9762.2 False True 11387.340276835865 10932.000635606568 11706.67560820011 10059.991291286447 10459.737555221081 7632.598211935826 15210.035942335779 10327.452422775921 11346.650218318446 9420.428349382426 1.2087921965440545 1.160456852933151 1.2426903718202542 1.0678910680262166 1.1103250475767155 0.8102177447627629 1.6145800783393147 1.096282678425441 1.204472853833902 1.0 13.201576945718806 -11.891681843567264 1.993659036841585 0.09650417322397972 1.1661638444632891 0.0670393526186589 0.18831019198773555 2861904.165990655 409251.55311185255 11570314.73738326 0.04665613887031676 1.2832703394739363e-12 11.891681843567264 1.0696596712393094 FVHGEGLR ddPTM_PC-9_Lapatinib_30min_R1 2 FVHGEGLR 8 0 B1AH87;P30536 B1AH87 TSPO Translocator protein 0 ; 133.6 0.0034679000000000003 1391400.0 32521.0 33562.0 16214.599999999999 13269.1 13355.8 12305.3 15358.900000000001 11794.1 24766.0 7912.7 False True 32057.244576378987 33484.289251043134 14881.49817816603 14244.953878419994 12570.238102513078 11779.031004055332 16154.108690325127 12342.096942478873 21976.59228245834 9280.399651989996 3.454295696145473 3.6080654397101424 1.603540659477417 1.5349504776300715 1.3544931871352806 1.2692374731436868 1.740669507359115 1.32991006910272 2.368065288841941 1.0 13.17997121970556 -5.269382725964451 8.515131099381236 1.5286003146875349 3.533980090725208 0.844751791889856 0.34400183567357207 0.043429515182309426 33.085989681564605 0.08514941192182811 0.19237266554646423 5.3779563632545955e-06 5.269382725964451 2.005379776037673 FVHGPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 FVHGPSPR 8 0 Q5T200-2;Q5T200;Q5T9K0 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 FVHGPS(1)PR;FVHGPS(1)PR;FVHGPS(1)PR 83.499 0.008482700000000001 32807200.0 151488.0 165015.0 253474.0 321184.0 284466.0 240748.0 219558.0 286351.0 237219.0 249250.0 True False 199658.03285385505 218352.87170579747 250112.76914303034 247139.99104333395 244972.8061405833 225693.9895018389 239098.23665979458 242102.03264136842 249757.91204781304 240523.83336579517 0.8300966688411693 0.907822183981745 1.039866884054904 1.0275072851823244 1.0184970142564709 0.9383435576573294 0.9940729503348946 1.0065615089094855 1.0383915329836542 1.0 17.875820331322046 -5.0273786501041595 3.3577646520479805 1.0059345705478635 0.8362333072398114 0.808373790534401 0.028183811301583123 0.10544535848724848 2.3665305044533613 0.007979872593045497 0.0335746741385491 9.389043472311382e-06 5.0273786501041595 -0.16970126330805213 FVIATSTK ddPTM_PC-9_Lapatinib_30min_R1 1 FVIATSTK 8 0 Q02878 Q02878 RPL6 60S ribosomal protein L6 0 117.4 0.016349000000000002 8027400.0 77178.0 76891.0 83776.0 75488.0 89670.0 75762.0 77762.0 54119.0 77786.0 82301.0 False True 76077.42756728825 76712.9636136688 76888.26066471181 81039.63934058603 84395.78689800293 72521.83586984791 81788.13586761185 56633.566311122864 69024.92155710673 96526.61819081075 0.7881497248448175 0.7947337744913539 0.7965498233111362 0.8395574284016606 0.8743265689798851 0.7513143755486082 0.8473117301792927 0.5867144977478795 0.7150869143748563 1.0 16.558639214536726 FVINYDYPNSSEDYIHR ddPTM_PC-9_AZD4547_30min_R2 1 FVINYDYPNSSEDYIHR 17 0 P17844-2;P17844;J3KTA4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 98.508 0.0011322 5046900.0 30139.0 27538.0 40986.0 61375.0 50434.0 42347.0 34379.0 39990.0 29075.0 51365.0 False True 39722.57506985603 36439.11996505928 40442.498860223335 47225.941984297475 43432.109654208754 39699.03539566014 37438.66439905215 33810.464378780955 30611.845142211074 49566.72698428923 0.801395966339407 0.7351528370353988 0.8159203022027675 0.9527750742805009 0.8762351742122308 0.8009210575522412 0.755318470209235 0.68212017286309 0.6175885922811459 1.0 15.59708437671894 -7.188678861586583 3.125569997338423 0.735670099877719 0.835824682714715 0.06922833468847278 0.10684065018578653 0.5172649324755669 9.899482316775641 0.04550244952403983 0.033011147629503024 6.476213213675758e-08 7.188678861586583 0.10015458283699596 FVINYDYPNSSEDYIHR ddPTM_PC-9_Lapatinib_30min_R1 5 FVINYDYPNSSEDYIHR 17 0 P17844-2;P17844;J3KTA4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 ;;;; 144.73 3.4571999999999996e-09 6200700.0 131491.0 110139.0 137038.0 110475.0 122961.0 135471.0 112461.0 106358.0 135133.0 116263.0 False True 129615.91422750383 109883.97991242005 125771.26462197771 118599.70003379663 115728.67573062728 129677.22112832531 118283.68030410097 111299.78095896817 119912.89852642489 136358.90463929024 0.950549687755093 0.8058438149169339 0.9223546122981848 0.8697613137002532 0.8487064048861639 0.9509992872952452 0.8674437552648021 0.8162267162044834 0.8793917701497389 1.0 17.05704939001432 -10.719984193652701 5.195794674171994 1.0000082894061977 0.8769167056464102 0.36694196074335583 0.04759428786113628 4.36716666460564e-06 6.748246732677879e-07 0.04403605446925015 0.010679592832777886 1.905530069343981e-11 10.719984193652701 -0.12309158375978746 FVINYDYPNSSEDYVHR ddPTM_PC-9_AZD4547_30min_R2 2 FVINYDYPNSSEDYVHR 17 0 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 ; 65.652 0.017789 5422900.0 22402.0 20020.4 26970.0 41308.0 32777.0 39516.0 32970.0 46543.0 38961.0 34998.0 False True 29525.370009453352 26491.60277973975 26612.360178115043 31785.07880223807 28226.47932220329 37045.05827319306 35904.26612864684 39350.84880174048 41020.39891954205 33772.730672562146 0.8742369782210279 0.7844080787125166 0.7879836675373018 0.9411462493336703 0.8357772309224384 1.0968925975325248 1.0631140986718144 1.1651663344388716 1.2146011916314514 1.0 15.043571211796687 -6.781571957348056 5.492797461476015 1.1177693929493924 0.8426481207989318 0.7903804008675052 0.06772101542288643 0.07888039951019986 6.910290218735481 0.02435322010053177 0.02228464964686481 1.653590782060292e-07 6.781571957348056 -0.27512127215046056 FVINYDYPNSSEDYVHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FVINYDYPNSSEDYVHR 17 0 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 55.851000000000006 0.042677 5721900.0 8887.8 9698.2 11287.0 12562.0 13559.0 11803.0 11440.0 10858.0 11848.0 9035.7 False True 10392.328997948365 10660.973202829076 11556.124886185864 11858.191866553498 10902.21128409592 11184.029902006 10356.320381572432 10572.98900500196 12021.254585786146 10673.800883438156 0.9736296480922243 0.9987982087403389 1.0826625878056946 1.1109624393455835 1.0213991625993486 1.0478019989448681 0.9702560966489137 0.9905552033865819 1.1262393515733224 1.0 13.381786383195012 -5.049224754477085 6.908162858353391 1.042536647909387 0.9794317815748786 0.19109397213413282 0.04852368586625873 0.34408439616752795 40.83939341073632 0.012869390945258095 0.035933198931660824 8.928433031802754e-06 5.049224754477085 -0.06310486633450829 FVINYDYPNSSEDYVHR ddPTM_PC-9_Lapatinib_30min_R1 1 FVINYDYPNSSEDYVHR 17 0 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 77.13 0.006612000000000001 3972200.0 32857.0 33708.0 36262.0 36148.0 48112.0 44613.0 37064.0 39921.0 44535.0 34467.0 False True 32388.453154764153 33629.95119701337 33280.67833536793 38806.44450619304 45282.14675183141 42705.00598798246 38982.99256445519 41775.87539877557 39518.99932565944 40424.57502560937 0.8012070166290122 0.8319184846274441 0.8232783724821916 0.9599716133468014 1.120163829134746 1.0564119959437648 0.9643389581649054 1.033427695215352 0.9775983866403979 1.0 15.302944986602286 -5.862320836786 3.6251851460200064 1.0265807476128677 0.8184521802366193 0.8280100168647023 0.041982853449227905 0.09193542420638813 2.3246276468988705 0.012748962490648202 0.020137739358024175 1.3730272708608312e-06 5.862320836786 -0.2081285673762484 FVIWT(ph)IFQTTGT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 FVIWTIFQTTGTR 13 0 F2Z2P8;F8WDC3;A0A087WZE3;Q9H7L2 F2Z2P8 KIR3DX1 Putative killer cell immunoglobulin-like receptor-like protein KIR3DX1 2 FVIWT(1)IFQT(0.008)T(0.008)GT(0.984)R 55.04 0.038209 463570.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FVKDFQDYMEPEEGCQGS(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 2 FVKDFQDYMEPEEGCQGSPQR 21 1 O43237;H3BUM4;B4E2E0 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 FVKDFQDYMEPEEGCQGS(1)PQR;FVKDFQDYMEPEEGCQGS(1)PQR 106.1 0.00011810000000000001 24053000.0 115051.0 74644.0 137310.0 266010.0 200289.0 141395.0 108569.0 140155.0 102504.0 147108.0 True False 151634.82479053747 98771.21325702248 135489.1796832399 204685.50431353127 172482.32958979683 132553.54829785737 118231.4306739782 118497.26519149906 107922.15217393651 141957.79369619032 1.0681683678111915 0.6957787289115439 0.9544328363767461 1.4418757785964686 1.2150254318472526 0.9337532293685872 0.8328632588289596 0.8347358894933229 0.7602411207158173 1.0 17.11510253179911 -6.979627119424544 9.590848095227997 0.8488057305439414 1.0684892427371053 0.23724775693962408 0.18546456517361032 0.46845946183505954 205.9065213174664 0.07380402683924825 0.0645069103853185 1.0480279874395927e-07 6.979627119424544 0.21968351219316395 FVKDFQDYMEPEEGCQGS(ph)PQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FVKDFQDYMEPEEGCQGSPQR 21 1 O43237;H3BUM4;B4E2E0 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 FVKDFQDYMEPEEGCQGS(1)PQR 79.845 0.0014306 8049000.0 28168.0 19516.0 28611.0 39326.0 41237.0 42867.0 42738.0 47866.0 34691.0 30075.0 True False 32936.28605664052 21453.419503249268 29293.194747821737 37122.691716612244 33156.905872281386 40618.97905695938 38689.54724367502 46609.56821821919 35198.290246075885 35527.35942643099 0.9270682254008777 0.6038562913090791 0.8245249638797734 1.04490433051983 0.9332780822324196 1.143315453575208 1.0890071164391544 1.3119344913526971 0.9907375840572523 1.0 15.116642843789599 -5.9574358079431 1.2422615646593276 1.1166668524846566 0.7480964955419366 0.5258646471547013 0.1238732967969112 0.33214410940210903 1.0397917686362923 0.044550580488730424 0.08921231845122889 1.1029712494158788e-06 5.9574358079431 -0.36857035694272 FVKDFQDYMEPEEGCQGS(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 1 FVKDFQDYMEPEEGCQGSPQR 21 1 O43237;H3BUM4;B4E2E0 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 FVKDFQDYMEPEEGCQGS(1)PQR 100.39 0.00030591 9938200.0 56524.0 32285.0 46774.0 36196.0 38479.0 33958.0 22033.0 22644.0 35763.0 23318.0 True False 55717.9573947679 32210.24606608449 42928.42227286139 38857.97458631635 36215.74087262471 32505.695499964324 23173.76093170304 23696.12290598619 31734.994338914526 27348.485230718063 2.0373324856831556 1.1777707538224331 1.5696819005040836 1.4208455882840167 1.324232057720947 1.1885738908659422 0.8473508033883378 0.8664510193555618 1.1603931285843025 1.0 14.739173307241842 -6.56322411105639 1.024305397241197 0.950674346788449 1.5795993705181623 0.6030825877319888 0.2131538268886168 0.3629425027125058 0.8191795148728672 0.10639889443034083 0.11864105450132814 2.733857596645111e-07 6.56322411105639 0.6289250237297134 FVLMAT(ph)PNLSR ddPTM_PC-9_AZD4547_30min_R2 1 FVLMATPNLSR 11 0 E7EUN2;A0A087X1U1;F5GXM9;Q9UPQ3-2;Q9UPQ3 E7EUN2 AGAP1 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 1 FVLMAT(1)PNLSR 122.52 0.0016164999999999999 16212000.0 20358.0 26112.0 40870.0 44403.0 41315.0 47718.0 39220.0 46096.0 35002.0 48743.0 True False 26831.420527294504 34552.19335200915 40328.03709601638 34166.57436951138 35579.12539881101 44734.185916596485 42710.50402079253 38972.922380702315 36852.134262000756 47036.52240621455 0.570438016135085 0.7345822264157023 0.8573770983266434 0.7263839378779675 0.7564148788795286 0.951052153266461 0.908028524131485 0.8285672576753493 0.7834791429464136 1.0 15.521493779588287 -3.783043841659432 0.4959623257216607 0.8773154923814052 5.171318655208797e-37 0.5722636015428124 0.07788338352803983 9.492321932810142 0.8423165459949751 0.04783078863062423 6.005685669269022 0.0001647996019328322 3.783043841659432 -0.8773154923814052 FVLMAT(ph)PNLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FVLMATPNLSR 11 0 E7EUN2;A0A087X1U1;F5GXM9;Q9UPQ3-2;Q9UPQ3 E7EUN2 AGAP1 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 1 FVLMAT(1)PNLSR 86.288 0.04202 32673000.0 140920.0 179180.0 276660.0 253840.0 317340.0 223810.0 248520.0 234970.0 208250.0 232990.0 True False 164774.97270313057 196967.8062406334 283256.62363889336 239618.16776038407 255159.50504425107 212073.00960501263 224978.38647101182 228802.2864712943 211295.2622797066 275229.2426521747 0.5986826512885025 0.7156499954096612 1.029166163120477 0.8706130404290117 0.9270799228507594 0.7705322572609888 0.8174218128243437 0.8313153219712441 0.7677064407968244 1.0 18.07027423658431 -1.5228827251058752 0.030159395414665793 1.4095967184209939 4.78496152087774e-09 0.1957563633507129 0.11118908448684496 3070.590654852662 7.12693581580915 106.03701936168522 257.8248572240654 0.02999972508465098 1.5228827251058752 -1.4095967136360323 FVLMAT(ph)PNLSR ddPTM_PC-9_Lapatinib_30min_R1 2 FVLMATPNLSR 11 0 E7EUN2;A0A087X1U1;F5GXM9;Q9UPQ3-2;Q9UPQ3 E7EUN2 AGAP1 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 1 FVLMAT(0.993)PNLS(0.007)R;FVLMAT(0.995)PNLS(0.005)R 119.21 0.0024138000000000002 33698000.0 73111.0 62537.0 73358.0 73884.0 66176.0 54088.0 47900.0 48114.0 60938.0 44850.0 True False 72068.42373308467 62392.1994187618 67326.78841006896 79317.6758297987 62283.65778702187 51774.78232528624 50380.02762349999 50349.55208879258 54074.520734411955 52602.26274113152 1.3700631869725992 1.1861124629905928 1.2799219064282539 1.5078757394931888 1.1840490226349167 0.9842691098685715 0.9577540014092609 0.9571746435429009 1.0279884916838231 1.0 15.68283723943198 -6.613995282453656 3.7369101815900123 0.9811637506146541 1.3241647334098838 0.8137466978237595 0.07894784859484802 0.09992513724568321 2.704522003155477 0.02804725936157157 0.028162578215986278 2.432230429159558e-07 6.613995282453656 0.3430009827952297 FVLSSGK ddPTM_PC-9_Lapatinib_30min_R1 1 FVLSSGK 7 0 P27797;K7EJB9 P27797 CALR Calreticulin 0 120.65 0.027485000000000002 7683600.0 74331.0 75534.0 79540.0 72864.0 69906.0 73069.0 72069.0 65952.0 71512.0 56279.0 False True 73271.026309364 75359.10566379497 73000.52823327896 78222.66162717855 65794.26652048403 69944.0092021583 75800.38018367474 69016.37068961313 63457.56550525564 66006.75016294635 1.1100535343504236 1.141687864919286 1.1059554977796597 1.1850706395039237 0.9967808801079014 1.0596493393401782 1.148373158753484 1.0455956477062898 0.9613799399092106 1.0 16.010325948393906 -7.593463697039321 0.48622513533421263 0.9827424210719445 1.1317787857728425 0.42732903132274846 0.05344841531861572 0.9701014219947571 0.5261922782318962 0.05697744228735542 0.04368803918503756 2.5499772331606136e-08 7.593463697039321 0.14903636470089798 FVNVVPTFGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FVNVVPTFGK 10 0 E9PR30;P62861 E9PR30 FAU 40S ribosomal protein S30 0 108.67 0.0091912 1720900.0 17907.0 16389.0 18694.0 18582.0 21994.0 19331.0 20126.0 17716.0 20118.0 17351.0 False True 20938.30142062842 18015.99160887234 19139.735857389795 17540.910783656822 17684.433585250066 18317.24832971939 18219.519580378204 17250.9737716536 20412.187690483257 20496.59894955958 1.0215500372601247 0.8789746851762185 0.9338005736703484 0.8557961653454577 0.8627984393298607 0.8936725734253088 0.8889045263175087 0.8416505496402993 0.9958816943589495 1.0 14.323096919247476 -8.283694241255686 23.357311799111482 0.9979409890780866 0.8948463249880513 0.4108538830960987 0.04821836784945583 377.82892590191074 396537.2188848405 0.04524446928543785 0.011733671009957465 5.203622210912449e-09 8.283694241255686 -0.10309466409003532 FVNVVPTFGK ddPTM_PC-9_Lapatinib_30min_R1 1 FVNVVPTFGK 10 0 E9PR30;P62861 E9PR30 FAU 40S ribosomal protein S30 0 119.68 0.0035446999999999996 6979000.0 46904.0 50602.0 51612.0 50086.0 58491.0 49616.0 49267.0 48189.0 44373.0 57598.0 False True 46235.14035885983 50484.8341779776 47368.660588081424 53769.49152199801 55050.67437773051 47494.039340545045 51817.80419471763 50428.03686259354 39375.24547159506 67553.73755548925 0.6844201672909936 0.7473285121568426 0.701199701188589 0.7959513931828164 0.8149167813625617 0.7030556866159036 0.7670605072318022 0.7464877397963583 0.5828729378482113 1.0 16.04374797150752 -11.177015704287738 3.2233608937295655 1.020532213370384 0.7325259000574035 0.6314727692329052 0.06243215114459199 93323792.13110323 121018732.87736806 16190001.230333026 0.015552368950800137 6.6524910005410095e-12 11.177015704287738 -0.28800631331298054 FVQSTQNNGT(ph)LK ddPTM_PC-9_AZD4547_30min_R2 2 FVQSTQNNGTLK 12 0 Q96BY6;A0A2R8YD85;Q96BY6-3;H7C0I3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 FVQSTQNNGT(1)LK;FVQSTQNNGT(1)LK 158.81 0.00019107 7308200.0 21542.0 24215.0 28699.0 24769.4 24781.0 40051.0 34518.0 30165.0 29955.0 28054.0 True False 28391.907898564572 32042.02519986602 28318.432508406528 19059.197513415213 21340.585901196577 37546.604638618664 37590.03512977348 25503.692372741345 31538.360145655468 27071.837998973024 1.0487617390308566 1.1835925289255034 1.0460476495715139 0.7040230336092521 0.7882946810632561 1.3869248419720523 1.3885291102583972 0.9420746524010979 1.1649877687230503 1.0 14.724505219890874 -6.756689357300279 24.99999627797587 1.186134549703587 0.9581012526887762 0.2680051143070531 0.1833382659571978 183.76078552866613 967156.8685735093 0.06773583629521542 0.06562711456874132 1.751098768892135e-07 6.756689357300279 -0.22803329701481068 FVQSTQNNGT(ph)LK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FVQSTQNNGTLK 12 0 Q96BY6;A0A2R8YD85;Q96BY6-3;H7C0I3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 FVQSTQNNGT(1)LK;FVQSTQNNGT(1)LK 141.59 0.00019286 8626600.0 47219.0 53371.0 44708.0 48302.0 50237.0 37186.0 39986.0 37132.0 39974.0 32010.0 True False 55212.244082238976 58669.32016334893 45774.00827603419 45595.79553719688 40393.42047932198 35235.9006977883 36198.23660642963 36157.3243446061 40558.544126621826 37813.15960897941 1.4601330503237777 1.551558260934557 1.2105311682328799 1.205818186279502 1.0682371136669002 0.9318422756034622 0.9572920375009791 0.9562100792026884 1.0726039438658936 1.0 15.20660078327174 -5.6424132192909955 1.0346829373849211 0.979857822401344 1.5529675310485558 0.9016402095349594 0.06434518762337235 0.18370070356191728 0.35289018845071246 0.023961359406531397 0.08546724056828699 2.2781734209164657e-06 5.6424132192909955 0.5731097086472118 FVQSTQNNGT(ph)LK ddPTM_PC-9_Lapatinib_30min_R1 2 FVQSTQNNGTLK 12 0 Q96BY6;A0A2R8YD85;Q96BY6-3;H7C0I3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 FVQSTQNNGT(1)LK;FVQSTQNNGT(1)LK 194.77 3.791e-05 8804900.0 36059.0 46515.0 27712.0 33060.0 36051.0 29812.0 30668.0 28479.0 31761.0 22237.5 True False 35544.79204758927 46407.29737537309 25433.626331413474 35491.34268492701 33930.551058993035 28537.01025516626 32255.83898032355 29802.238307700944 28183.741721842824 26081.22224539381 1.3628499352198424 1.7793375225568295 0.9751700319913226 1.360800592510388 1.30095709241485 1.0941592378864133 1.23674568150349 1.1426703099761477 1.080614300076383 1.0 14.670723859779878 -1.522878745280984 0.20968648855519664 1.013200592459183 3.644885807699154 0.38224722229819597 0.17710259233557107 51.937360490908446 0.64595244877824 0.2896401362451077 45.55848018656729 0.029999999999955347 1.522878745280984 2.6316852152399712 FVS(ph)EGDGGR ddPTM_PC-9_AZD4547_30min_R2 1 FVSEGDGGR 9 0 Q53EL6;Q53EL6-2 Q53EL6 PDCD4 Programmed cell death protein 4 1 FVS(1)EGDGGR 90.149 0.008796600000000002 59208000.0 48288.0 66898.0 83243.0 114380.0 96076.0 88271.0 65512.0 99101.0 84191.0 62987.0 True False 63642.57954720482 88521.47023830832 82139.14342999004 88011.458153384 82737.50579247641 82751.40041585741 71342.44108643968 83787.21756443041 88641.16438066706 60781.84430175067 1.0470656209649063 1.4563801288892229 1.3513762929306874 1.4479892666048806 1.3612207188338534 1.3614493170861872 1.1737459089306514 1.3784908721833096 1.4583493705885127 1.0 15.891352830727877 FVS(ph)EGDGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FVSEGDGGR 9 0 Q53EL6;Q53EL6-2 Q53EL6 PDCD4 Programmed cell death protein 4 1 FVS(1)EGDGGR;FVS(1)EGDGGR 99.788 0.0040285 42672000.0 64029.0 77587.0 61065.0 122343.0 173285.0 190008.0 262530.0 202533.0 202068.0 233100.0 True False 74867.84506960498 85289.32460538049 62521.02119030211 115488.5183513576 139331.04818678103 180043.64599003288 237661.25784739625 197216.72335145136 205022.86222490142 275359.1847814148 0.27189158454633156 0.3097384409860333 0.22705260854084983 0.41941044546247663 0.5059974603621251 0.6538501562348641 0.8630954439963793 0.7162162522670367 0.7445651845158255 1.0 18.070955205742386 -6.593411534428386 0.9919311625084688 0.8304570560252971 0.2600112690385564 0.9017134732272335 0.07873111821078034 0.15525847637056683 0.33035373137081414 0.04149655946261188 0.04509183324335638 2.5502835263884075e-07 6.593411534428386 -0.5704457869867406 down FVS(ph)EGDGGR ddPTM_PC-9_Lapatinib_30min_R1 4 FVSEGDGGR 9 0 Q53EL6;Q53EL6-2 Q53EL6 PDCD4 Programmed cell death protein 4 1 FVS(1)EGDGGR;FVS(1)EGDGGR;FVS(1)EGDGGR;FVS(1)EGDGGR 94.40899999999999 0.005756600000000001 136402000.0 91434.0 108066.0 98173.0 112450.0 197506.0 313723.0 349509.0 328866.0 328692.0 229145.0 True False 90130.13439305784 107815.77981655537 90101.59489873906 120719.94812220309 185889.08539173615 300305.798614032 367604.8658593291 344146.31494435784 291671.24567979487 268752.40793348063 0.3353649371408278 0.40117140026980164 0.3352587446250538 0.4491864800410744 0.6916741205077719 1.1174069133860978 1.3678198036845706 1.2805329544416142 1.0852786321899186 1.0 18.03591815527148 -6.600083024383369 2.0660415638991525 1.2155579508134253 0.3722315747264415 0.9334349770132996 0.09995023617534143 0.07294202517802433 0.6339025103414506 0.03813056910593914 0.039097588024701875 2.5114062783003856e-07 6.600083024383369 -0.8433263760869838 down FVS(ph)FTSR ddPTM_PC-9_AZD4547_30min_R2 1 FVSFTSR 7 0 Q8N5V2-3;Q8N5V2 Q8N5V2-3 NGEF Ephexin-1 1 FVS(0.676)FT(0.32)S(0.005)R 72.87899999999999 0.037712999999999997 6395100.0 7557.0 9543.8 11306.0 16402.0 12353.0 12004.0 9158.6 14085.0 9061.4 11429.0 True False 9959.968804635255 12628.646710818964 11156.075052790831 12620.772308373895 10637.999178301163 11253.38798237194 9973.69765744085 11908.48689110102 9540.367104785255 11028.87418871685 0.9030811879987583 1.1450531119249479 1.0115334404851688 1.1443391313036868 0.964558938317061 1.020356909491703 0.9043259979921157 1.0797554389807131 0.8650354461877513 1.0 13.428997909803273 -6.348346521507318 24.999973382895604 0.9753265755737964 1.0549103572443017 0.170052747117848 0.08480566212440355 129.00137094663427 37105.908420704756 0.02434838355260024 0.027608472686278068 4.4838748092077587e-07 6.348346521507318 0.07958378167050528 FVS(ph)FTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FVSFTSR 7 0 Q8N5V2-3;Q8N5V2 Q8N5V2-3 NGEF Ephexin-1 1 FVS(0.968)FT(0.032)SR 69.628 0.046066 4198600.0 32433.0 21777.0 20530.0 22540.0 27360.0 20767.0 17056.0 23796.0 15604.0 10675.0 True False 37923.26631905073 23938.876640820832 21019.51306045857 21277.156875665958 21999.004405403375 19677.941961785884 15440.33220525344 23171.380213946108 15832.178980132274 12610.2929967465 3.0073263427610337 1.8983600656223567 1.6668536619951397 1.6872848934719866 1.744527618119515 1.5604666732852965 1.224422954267367 1.8374973698013524 1.25549652051836 1.0 13.622314176234013 -2.047324847630105 0.857396002863735 1.485874982955611 199.9999999999998 0.783741072633674 0.24174907219158412 110.42867278352342 0.821345437236731 0.07891129196114903 42088.564181548674 0.008967577783432025 2.047324847630105 198.5141250170442 up FVS(ph)FTSR ddPTM_PC-9_Lapatinib_30min_R1 1 FVSFTSR 7 0 Q8N5V2-3;Q8N5V2 Q8N5V2-3 NGEF Ephexin-1 1 FVS(0.984)FT(0.014)S(0.002)R 80.455 0.025381 5849700.0 13539.0 12039.0 14505.0 17074.0 10681.0 9814.4 8901.4 8681.7 15271.0 14394.0 True False 13345.931377251478 12011.12443517395 13312.454890919184 18329.678917194306 10052.764579653955 9394.66099048383 9362.2709371153 9085.083476104055 13551.019169240935 16881.983721200602 0.7905428412711649 0.7114758924977657 0.7885598701414005 1.0857538557021393 0.5954729459328627 0.5564903476767307 0.5545717311264816 0.5381526025697381 0.8026911643223184 1.0 14.043196817752584 -4.757125487038859 22.26087674436979 0.7193283258934571 0.7905432501417011 0.0 0.18074126056959164 238.85822864980793 1231865.013010902 0.04728143586018029 0.3463087573958637 1.749341152938743e-05 4.757125487038859 0.07121492424824405 FVSEAELDER ddPTM_PC-9_Lapatinib_30min_R1 1 FVSEAELDER 10 0 H3BPH9;H3BPF9;H3BN22;Q6P4H7;H3BSF0;H3BQQ6;H3BTI2;H3BTP8;H3BSY6;H3BP64;H3BUL4;H3BMX9;Q9GZU8 H3BPH9 FAM192A;NIP30 Protein FAM192A 0 88.177 0.036363 0.0 8618.9 9747.4 19456.0 9678.9 13968.0 11169.0 13050.0 11790.0 15989.0 13330.0 False True 8495.992905487314 9724.830494178472 17856.402782331865 10390.718593863885 13146.429702144604 10691.327906210654 13725.66514585959 12337.806441511095 14188.150448365757 15634.072738891491 0.5434280016078337 0.6220279677979799 1.1421465846140066 0.6646200748456171 0.8408832376378421 0.683847906093899 0.8779327930153142 0.7891613815266083 0.9075146754991844 1.0 13.93240603471433 -1.8756960692013807 0.11467963673564768 1.0312793270816736 1.2543571914717506e-29 0.25437393947659026 0.15087639211752774 161.70770362468053 1.3975571247499228 1.2878175403565442 26.236174512004833 0.013313858311475033 1.8756960692013807 -1.0312793270816736 FVSEDDRNS(ph)FTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FVSEDDRNSFTLK 13 1 A0A087WYC1;P34932 A0A087WYC1 HSPA4 Heat shock 70 kDa protein 4 1 FVSEDDRNS(0.728)FT(0.272)LK 52.463 0.043654000000000005 17638000.0 56794.0 49626.0 46356.0 56244.0 59599.0 53740.0 62804.0 49917.0 53860.0 47490.0 True False 66408.10246736872 54552.54131319168 47461.30284610898 53092.83102550829 47921.00378500127 50921.779796136834 56854.750458415634 48606.731641433325 54647.60060689079 56099.561069366864 1.1837544038046106 0.9724236745050054 0.8460191477687906 0.9464036796982999 0.8542135245184388 0.9077037114991376 1.0134615917603167 0.866436933104188 0.9741181493259683 1.0 15.775701862584498 -4.787096445724397 3.6671544744450877 0.9211783214628115 1.210766361862643 0.650482793617242 0.056275355216855207 0.1479830953042713 3.4325190345912238 0.013484266463428785 0.11650923687137847 1.6326893289859993e-05 4.787096445724397 0.28958804039983144 FVSEDDRNS(ph)FTLK ddPTM_PC-9_Lapatinib_30min_R1 1 FVSEDDRNSFTLK 13 1 A0A087WYC1;P34932 A0A087WYC1 HSPA4 Heat shock 70 kDa protein 4 1 FVSEDDRNS(0.991)FT(0.009)LK 71.545 0.012103000000000001 21602000.0 205840.0 153500.0 174230.0 142160.0 184710.0 186960.0 158960.0 141510.0 180840.0 136350.0 True False 202904.6838535673 153144.58018101216 159905.48194724947 152614.92063185794 173845.72095383215 178964.15662504637 167190.1710027466 148085.07120765338 160471.89487037717 159917.9158250452 1.2688052042621094 0.9576449229650837 0.9999222483751643 0.9543328516038381 1.0870934632741485 1.1191001064623571 1.0454749246835948 0.9260067606787892 1.0034641462307328 1.0 17.28697204942798 -4.753826755050001 24.999321729232488 1.0128452669708725 1.2688056603190438 0.6503176944634701 0.05683248857079571 192.99256862723885 633722.2453373056 0.015555421852102702 0.1618501769168329 1.7626790586703495e-05 4.753826755050001 0.25596039334817133 FVSISDLLVPK ddPTM_PC-9_Lapatinib_30min_R1 1 FVSISDLLVPK 11 0 P50395;P50395-2 P50395 GDI2 Rab GDP dissociation inhibitor beta 0 119.22 0.004543600000000001 3610500.0 34499.0 28071.0 34598.0 30289.0 37552.0 40641.0 33013.0 28040.0 37337.0 37039.0 False True 34007.03793365821 28006.003324177087 31753.48599214217 32516.554101141992 35343.265190072605 38902.87916879822 34722.25160615042 29342.840765052653 33131.71388395971 43441.14179863478 0.7828302048618563 0.6446884719097606 0.7309542216760998 0.7485197845827314 0.8135896923221142 0.8955307700963978 0.7992941752567294 0.6754620056044385 0.7626805491793252 1.0 15.406774402709672 -6.044748830504167 2.7200924302836684 0.8102209598745069 0.7124638967376032 0.2308807677075666 0.08588413234537275 0.46554681703938233 6.8538772302927375 0.026998123883950863 0.03920549142481812 9.020927022856476e-07 6.044748830504167 -0.09775706313690369 FY(ph)LKMFEDY(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 FYLKMFEDYPK 11 1 P31213 P31213 SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 2 FY(1)LKMFEDY(1)PK 56.431999999999995 0.042113 0.0 7679.3 3483.9 2518.7 3963.1 3003.5 2903.9 3018.7 757.82 4138.8 1480.6 True False 7569.791773788854 3475.8332436001797 2311.622208463161 4254.559594514042 2826.840035108198 2779.7069663215266 3174.9935153874617 793.031083757925 3672.6447605038593 1736.5197372245102 4.359174048829239 2.0016088323623804 1.3311810737940937 2.450049661580081 1.62787670909307 1.6007344499086136 1.8283659248596118 0.456678416466162 2.114945590180201 1.0 10.761983093098245 -4.7621013494675495 3.446805262600317 1.579695842557816 4.775081486143481 0.7168516128247666 0.5264147833439289 0.16874633595247235 3.1659178809840607 0.1300068389200561 1.4666168226035243 1.7294127263818804e-05 4.7621013494675495 3.195385643585665 FY(ph)LT(ph)PPQVNS(ph)ILKANEYSFKVPEFDGK ddPTM_PC-9_AZD4547_30min_R2 1 FYLTPPQVNSILKANEYSFKVPEFDGK 27 2 E5RIE5;E5RI96;E5RIV4;Q9P0J1;Q9P0J1-2 E5RIE5 PDP1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial 3 FY(0.992)LT(0.991)PPQVNS(0.92)ILKANEY(0.047)S(0.05)FKVPEFDGK 44.258 0.020309 8727500.0 29037.0 19280.0 30706.0 57377.0 39827.0 29957.0 20468.0 24343.0 19127.0 35081.0 True False 38270.161992879934 25511.882959050887 30298.81837705602 44149.61911581326 34297.70851406142 28083.784054308227 22289.612348230006 20581.348696490735 20138.014171455576 33852.82486782536 1.1304865145612393 0.7536116427110362 0.8950159549566228 1.304163516285291 1.0131416993403966 0.8295846554595748 0.6584269535927165 0.6079654733939739 0.5948695345242899 1.0 15.046988604864053 -6.959329963476786 3.150143748535207 0.6853391742783639 1.012852329114611 0.4086679871015043 0.17158908736105166 0.24975279060961544 5.092790679630609 0.06857352680513033 0.057210901858465814 1.0981711660033592e-07 6.959329963476786 0.3275131548362471 FY(ph)SHQLK ddPTM_PC-9_Lapatinib_30min_R1 1 FYSHQLK 7 0 Q9UI47 Q9UI47 CTNNA3 Catenin alpha-3 1 FY(0.909)S(0.091)HQLK 86.866 0.03188 19762000.0 35102.0 31885.0 30929.0 28133.0 32333.0 32175.0 29315.0 31371.0 33270.0 23687.0 True False 34601.43904308159 31811.17224150855 28386.137009392598 30201.994668936833 30431.236509123795 30798.95025358831 30832.78726060336 32828.61118546602 29522.782251368364 27781.266389056465 1.2454953837781748 1.1450583928038478 1.021772607910142 1.087135274756011 1.0953869446754667 1.1086229771627893 1.109840956449305 1.181681595278097 1.0626866982204206 1.0 14.761824744583997 FYCDYCDTYLT(ph)HDSPSVR ddPTM_PC-9_Lapatinib_30min_R1 1 FYCDYCDTYLTHDSPSVR 18 0 A0A0A0MRR7;P09234 A0A0A0MRR7 SNRPC U1 small nuclear ribonucleoprotein C 1 FYCDYCDTY(0.025)LT(0.917)HDS(0.052)PS(0.005)VR 158.15 2.1919e-05 13992000.0 126390.0 100460.0 131350.0 99901.0 100270.0 111760.0 68672.0 84378.0 97024.0 80913.0 True False 124587.65542291253 100227.39104224417 120550.9100256628 107248.05279996638 94372.31573840481 106980.28532528452 72227.5001453234 88298.50991703323 86096.1354119857 94898.70424020443 1.3128488573201211 1.0561513125463962 1.2703114440901992 1.1301318986242814 0.9944531539601716 1.127310285022434 0.7611010152731228 0.9304501112421407 0.9072424760833618 1.0 16.5341007681763 -6.5621808201556275 1.0952867558348054 0.9036907223338525 1.2029207082264872 0.5885871405715755 0.1021788883516442 0.3387561984210545 0.8657120030546072 0.04830358632891814 0.0533175519321384 2.740432944711135e-07 6.5621808201556275 0.2992299858926347 FYCDYCDTYLTHDS(ph)PSVR ddPTM_PC-9_AZD4547_30min_R2 3 FYCDYCDTYLTHDSPSVR 18 0 A0A0A0MRR7;P09234 A0A0A0MRR7 SNRPC U1 small nuclear ribonucleoprotein C 1 FYCDYCDTYLTHDS(0.875)PS(0.125)VR;FYCDYCDTYLTHDS(0.932)PS(0.068)VR;FYCDYCDTY(0.003)LT(0.002)HDS(0.831)PS(0.164)VR 169.7 4.5618e-08 33640900.0 108605.0 116917.0 149339.0 225549.0 175663.0 150842.0 109713.0 171818.0 116489.0 150004.6 True False 143139.1308756664 154708.13381345166 147358.66728363073 173552.16274731254 151275.224614095 141409.82589444748 119477.24445775624 145267.47608485562 122646.37072299303 144752.98461184683 0.988850981273319 1.068773360551421 1.018000890819426 1.1989539505018865 1.0450577238164551 0.9769043883525858 0.8253870880668392 1.0035542719508574 0.8472804277705749 1.0 17.14323356938928 -6.858822961371556 3.4111265462530205 0.9176920486118259 1.0701116754749895 0.4615863851261982 0.07377030030344338 0.2070777923720739 4.735937847668873 0.026586842235738133 0.023485387536370944 1.3841304999461722e-07 6.858822961371556 0.15241962686316368 FYCDYCDTYLTHDS(ph)PSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FYCDYCDTYLTHDSPSVR 18 0 A0A0A0MRR7;P09234 A0A0A0MRR7 SNRPC U1 small nuclear ribonucleoprotein C 1 FYCDYCDTYLTHDS(0.85)PS(0.149)VR;FYCDYCDTYLT(0.003)HDS(0.913)PS(0.085)VR 147.75 2.4423000000000003e-05 17518400.0 46410.0 44661.0 55263.0 48324.0 59064.0 50308.0 40645.0 38666.0 41132.0 31676.0 True False 54266.29636071736 49094.648925733534 56580.67950609458 45616.562948521816 47490.83319447167 47669.75991782753 36794.8113556828 37651.05847001346 41733.477685901074 37418.608052921976 1.4502489318674634 1.3120383541872502 1.5121000606455284 1.2190876497598544 1.2691769059742768 1.2739586638393154 0.983329238320225 1.006212160985858 1.1153134725609377 1.0 15.19146827184014 -6.797975234561018 0.8842725689205283 1.0121134589167458 1.4054782125085246 0.7650254437121403 0.08574226993735856 0.278515134536928 0.47052479160799804 0.054349911190722175 0.04870911666168636 1.5922995245953013e-07 6.797975234561018 0.3933647535917788 FYCDYCDTYLTHDS(ph)PSVR ddPTM_PC-9_Lapatinib_30min_R1 3 FYCDYCDTYLTHDSPSVR 18 0 A0A0A0MRR7;P09234 A0A0A0MRR7 SNRPC U1 small nuclear ribonucleoprotein C 1 FYCDYCDTYLTHDS(0.89)PS(0.11)VR;FYCDYCDTYLT(0.002)HDS(0.857)PS(0.141)VR;FYCDYCDTY(0.002)LT(0.082)HDS(0.856)PS(0.061)VR 190.91 2.1714000000000004e-11 29904600.0 113957.0 113469.0 150571.0 115336.0 119179.0 117955.0 94265.0 94336.0 119930.0 84452.0 True False 112331.9522828458 113206.26950201431 138191.63360086802 123818.19418961715 112169.1255349292 112910.3396165348 99145.58045781254 98719.19495049973 106422.22048111224 99049.41567478354 1.1341001006171891 1.1429271816576188 1.3951786859056605 1.2500648625344628 1.1324562065385888 1.1399394822000957 1.0009708768332843 0.9966661012381128 1.0744356214128146 1.0 16.595860843754785 -6.859541599996 1.6198511333172803 1.0178947376552392 1.230894174537662 0.605842417779336 0.07410593769877707 0.27223141455256666 1.4734598461645245 0.036050342532140185 0.030320724471061645 1.381842036325301e-07 6.859541599996 0.21299943688242284 FYCDYCDTYLTHDSPS(ph)VRK ddPTM_PC-9_AZD4547_30min_R2 1 FYCDYCDTYLTHDSPSVRK 19 1 A0A0A0MRR7;P09234 A0A0A0MRR7 SNRPC U1 small nuclear ribonucleoprotein C 1 FYCDYCDTYLT(0.02)HDS(0.391)PS(0.589)VRK 65.467 0.0038734000000000004 7277600.0 33938.0 25522.0 34487.0 66895.0 56097.0 43937.0 27888.0 52381.0 32745.0 45484.0 True False 44729.578045747156 33771.48739008798 34029.67984659451 51473.39126744733 48308.89985470417 41189.61244430821 30369.977973785364 44286.72004563452 34475.833849757575 43891.619004252105 1.019091550061388 0.7694290654171652 0.7753115655929166 1.172738496214066 1.1006406450858905 0.9384391229751143 0.6919311399937924 1.0090017422538946 0.7854764675328483 1.0 15.421657866569216 -10.256425848467318 14.470771570841247 0.9999999654823571 0.9189315047914602 0.0257890244455119 0.1510888840967393 0.0 0.0 0.15279879676852579 0.03705915167905402 5.540821399657189e-11 10.256425848467318 -0.0810684606908969 FYCDYCDTYLTHDSPS(ph)VRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FYCDYCDTYLTHDSPSVRK 19 1 A0A0A0MRR7;P09234 A0A0A0MRR7 SNRPC U1 small nuclear ribonucleoprotein C 1 FYCDYCDTYLTHDS(0.088)PS(0.912)VRK 94.339 0.00028179 3354900.0 19473.0 11258.0 16726.0 22866.0 24364.0 24140.0 19942.0 17464.0 19459.0 15958.0 True False 22769.39429071856 12375.619838469993 17124.811273708227 21584.892152572218 19590.04909843742 22874.05590395874 18052.949392422845 17005.588504637537 19743.551062188784 18851.059076541507 1.2078575637722697 0.6564946716373282 0.9084270121999966 1.1450227843926672 1.0392015121747467 1.2134095920596577 0.957662342424472 0.9021025522008735 1.0473443949235672 1.0 14.202357957767695 -4.474263676129982 23.58631425394946 0.9893874068057841 4.270150606240065 0.17692000557907162 0.1436518983944496 886.9350806046446 491344.1710049199 0.036360296109677344 20921.91665043524 3.355338374733959e-05 4.474263676129982 3.2807631994342814 FYCDYCDTYLTHDSPS(ph)VRK ddPTM_PC-9_Lapatinib_30min_R1 2 FYCDYCDTYLTHDSPSVRK 19 1 A0A0A0MRR7;P09234 A0A0A0MRR7 SNRPC U1 small nuclear ribonucleoprotein C 1 FYCDYCDT(0.002)Y(0.005)LT(0.257)HDS(0.305)PS(0.43)VRK;FYCDYCDTY(0.001)LT(0.034)HDS(0.423)PS(0.542)VRK 73.707 0.0017235 11794100.0 60322.0 51861.0 95808.0 67225.0 61934.0 57013.0 38723.0 46217.0 68103.0 34476.0 True False 59461.79721830004 51740.91904083034 87931.0360695752 72168.95075602601 58291.16388692897 54574.686893794285 40727.88746690585 48364.41054345362 60432.522983617 40435.13066361762 1.4705479181696344 1.2796031122358988 2.174619807737954 1.7848081500318131 1.4415970204685822 1.349684939757077 1.0072401596948872 1.1960987821654434 1.4945549078685791 1.0 15.303321652991674 -6.656414781546434 2.4019408049223836 1.1968256339088001 1.6786402031438155 0.43228856507304925 0.2535807279318037 0.30413276092471864 3.57950278700647 0.09941452739117432 0.09805970326460854 2.205896941072066e-07 6.656414781546434 0.4818145692350153 FYDS(ph)NTVK ddPTM_PC-9_AZD4547_30min_R2 2 FYDSNTVK 8 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 FYDS(0.98)NT(0.02)VK;FYDS(0.5)NT(0.5)VK 108.31 0.003796 10388200.0 31197.0 33907.0 46907.0 58595.0 64058.0 45897.0 39441.0 44189.0 43137.0 47485.0 True False 41116.99706208893 44866.77466247602 46284.98253151065 45086.82803372566 55164.652421566934 43027.053334465585 42951.17259265879 37360.60541220183 45417.13375406912 45822.56460330915 0.8973089441423276 0.9791415005007357 1.0100914894704105 0.9839437932827889 1.2038752719131556 0.9389926929440855 0.9373367240461483 0.8153320473359926 0.9911521571795492 1.0 15.483770585397071 -6.972395754125141 24.99913671624351 0.9230800968163474 1.0169563726779376 0.164946547468234 0.08613040933567791 345.69196277918473 313066.782190378 0.030801810585945055 0.027164165391821572 1.0656246201740729e-07 6.972395754125141 0.0938762758615902 FYDS(ph)NTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 FYDSNTVK 8 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 FYDS(0.986)NT(0.014)VK;FYDS(0.997)NT(0.003)VK;FYDS(0.786)NT(0.214)VK 118.23 0.003512 16823800.0 86546.0 77229.0 75179.0 89766.0 105683.0 82374.0 82944.0 83465.0 87076.0 65061.0 True False 101196.52843858335 84895.78473131989 76971.55247794517 84736.70204529878 84975.17480176338 78054.16242886068 75086.94385744266 81274.13218847735 88349.32176839233 76856.04427740736 1.3167022761842966 1.104607783675329 1.0015029162849038 1.1025379050142972 1.1056407547472844 1.0155891207089554 0.9769816357763713 1.0574852368816063 1.1495429227335805 1.0 16.229871103436114 -4.781116729376702 3.413317084584605 1.0528768964490163 1.3505166742578931 0.697548004151005 0.052281099305883094 0.17319148856365899 3.248996046880619 0.013647876024275394 0.1357518619933131 1.6553249865431628e-05 4.781116729376702 0.29763977780887685 FYDS(ph)NTVK ddPTM_PC-9_Lapatinib_30min_R1 3 FYDSNTVK 8 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 FYDS(0.998)NT(0.002)VK;FYDS(0.871)NT(0.129)VK;FYDS(0.777)NT(0.223)VK 141.71 0.0021833 25086700.0 152742.0 133187.0 134232.0 133729.0 152141.0 136916.0 110150.0 114141.0 118158.0 92009.0 True False 150563.87107054752 132878.61368448506 123195.96311050453 143563.87676686628 143192.3655007145 131060.42184678483 115853.02803191073 119444.40755220693 104849.80178109944 107912.63305571387 1.3952386000331711 1.2313536415693016 1.1416268848421118 1.3303713634041914 1.326928659286686 1.2145049021194771 1.0735816998561913 1.10686213624812 0.9716174910398754 1.0 16.71950424176481 -7.323829477043235 1.6991083996000986 1.0217553509213158 1.278013979315498 0.7363372161973862 0.07046459072489268 0.21598964932020903 1.2134136987434798 0.04202042109194753 0.024446271343401445 4.744282299107621e-08 7.323829477043235 0.25625862839418234 FYDSNT(ph)VK ddPTM_PC-9_AZD4547_30min_R2 2 FYDSNTVK 8 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 FYDS(0.072)NT(0.928)VK;FYDS(0.035)NT(0.965)VK 141.1 0.0057 21257900.0 75420.0 92861.0 94928.0 113480.0 118676.0 106143.0 99739.0 112345.0 83799.0 117042.0 True False 99401.99116654655 122876.50225417144 93669.19269514669 87318.93924852266 102199.88589687264 99505.86143059858 108615.57777995484 94984.66168127382 88228.44406095093 112944.39520481223 0.8800967147266757 1.0879380250020236 0.8293390081489915 0.7731144081136507 0.9048690349932318 0.8810163731467653 0.9616730213393275 0.8409860578652849 0.7811670858120792 1.0 16.785253154102286 -5.283735435950973 24.992588878504694 0.8670769212910132 0.9840174055466142 0.22767451185066445 0.08255475306710804 946.8627186569175 1061377.1295011675 0.02111925570477184 0.044017445314949596 5.203128648424184e-06 5.283735435950973 0.116940484255601 FYDSNT(ph)VK ddPTM_PC-9_Lapatinib_30min_R1 1 FYDSNTVK 8 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 FYDS(0.269)NT(0.731)VK 138.25 0.0073731000000000005 12149000.0 76096.0 57170.0 70427.0 55643.0 71035.0 62442.0 54220.0 53428.0 69112.0 38764.0 True False 75010.85708570253 57037.62637751433 64636.7639160817 59735.17183960662 66856.86096018339 59771.50121941135 57027.24629950246 55910.45992850336 61327.87877837597 45464.30575021676 1.649884581935905 1.2545583933664795 1.4217035287242572 1.3138916531090288 1.4705351782450706 1.3146907278821998 1.2543300806750046 1.2297660550603877 1.348923683456523 1.0 15.472446702295704 -13.603472320141824 0.08299987148136055 7.1271616353686615e-12 1.7071862651855918 0.597089045568469 0.10265110044239044 137.3925570094919 0.9609226095910144 26.93202726421406 3.2429501249556147 2.4918831869378595e-14 13.603472320141824 1.7071862651784646 FYEAFSK ddPTM_PC-9_AZD4547_30min_R2 1 FYEAFSK 7 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 98.29899999999999 0.018368000000000002 0.0 30214.0 31527.0 37142.0 54586.0 39935.0 32050.0 29053.0 32999.0 38400.0 28024.0 False True 39821.4235097591 41717.4862059127 36649.47281184832 42002.04104529311 34390.714578277104 30045.908433440556 31638.660716881324 27899.762791582707 40429.74560484627 27042.888289841736 1.4725284918888428 1.5426416645585619 1.3552351516245087 1.5531640183963102 1.271710115046974 1.111046575773005 1.169943845412619 1.0316857612455117 1.4950232080067094 1.0 14.722961625063828 -6.448555403430454 4.129626194613284 1.1653323269114726 1.4749100393990229 0.5533684959369525 0.13519398015710563 0.17272053021511857 5.575893908418085 0.041561472596918336 0.04640354833187206 3.559955723876133e-07 6.448555403430454 0.3095777124875503 FYEAFSK ddPTM_PC-9_Lapatinib_30min_R1 2 FYEAFSK 7 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 ; 126.67 0.020929 55227000.0 149563.0 149445.0 176818.0 156673.0 145468.0 148201.0 156943.0 132651.0 134847.0 138807.0 False True 147430.20419350464 149098.96928437368 162280.70657721782 168195.25506580676 136911.85824109195 141862.7887034044 165068.7406120034 138814.44972628378 119659.11085813842 162799.60500129862 0.9055931320738071 0.9158435567652904 0.9968126555093505 1.0331428940780605 0.8409839706920654 0.8713951652540728 1.0139382132449688 0.8526706789317854 0.7350086067910541 1.0 17.31273767365179 -6.274629042021951 24.975089568020202 0.8839996995202669 0.9619166417043573 0.1754079288538386 0.08192383717780093 1455.3283734954139 2755709.1054397672 0.02627224565660905 0.029967089102094096 5.31338099434425e-07 6.274629042021951 0.0779169421840904 FYEEVHDLER ddPTM_PC-9_AZD4547_30min_R2 4 FYEEVHDLER 10 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;A8MXH2;E9PKT8;C9JZI7;E9PNW0;E9PJJ2;F8VVB5;P55209;F8W020;P55209-2;P55209-3;F8W0J6;H0YIV4;B7Z9C2;H0YHC3;F8VV59;F5H4R6;F8VY35;F8VUX1;F8VXI6;F8W118;F8VRJ2;F8W543;H0YH88 E9PNJ7;P55209 NAP1L4;NAP1L1 Nucleosome assembly protein 1-like 4;Nucleosome assembly protein 1-like 1 0 ;;; 161.51 9.3785e-05 129409000.0 173540.0 162269.0 234486.0 296122.0 270657.0 228986.0 209035.0 274787.0 208068.0 241301.0 False True 228722.11014376127 214719.28090675475 231376.56242956946 227855.6479392936 233080.94742989232 214667.46922121133 227638.7100455469 232324.98312708354 219066.04970075918 232853.12543630818 0.9822591374506723 0.9221232504585233 0.9936588224702931 0.9785380699200383 1.000978393539521 0.9219007424486079 0.9776064187199945 0.9977318650619997 0.9407906777728858 1.0 17.829060721083785 -11.046733307768022 3.258783273926236 1.0008749733369013 0.9688029322417973 0.10077508435827442 0.028296284193920516 40747694.77359808 8132122283.52221 8046304.109179515 0.00687091766771427 8.979800582159796e-12 11.046733307768022 -0.03207204109510409 FYEEVHDLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 FYEEVHDLER 10 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;A8MXH2;E9PKT8;C9JZI7;E9PNW0;E9PJJ2;F8VVB5;P55209;F8W020;P55209-2;P55209-3;F8W0J6;H0YIV4;B7Z9C2;H0YHC3;F8VV59;F5H4R6;F8VY35;F8VUX1;F8VXI6;F8W118;F8VRJ2;F8W543;H0YH88 E9PNJ7;P55209 NAP1L4;NAP1L1 Nucleosome assembly protein 1-like 4;Nucleosome assembly protein 1-like 1 0 ;;;;; 138.25 9.3785e-05 105959400.0 214923.0 234051.0 272437.0 279326.0 297683.0 260499.0 274740.0 263126.0 259363.0 207384.0 False True 251305.21897725633 257286.03649082754 278932.9313030763 263676.2698071099 239354.1530852959 246837.97385771968 248714.6382546505 256219.22130504198 263155.6932084107 244981.07754915912 1.0258148159497265 1.0502282015605848 1.1385896988191024 1.0763128011558334 0.9770311873873847 1.0075797540248306 1.0152402003568712 1.0458735175316867 1.0741878345914475 1.0 17.902310793541112 -6.219437839642549 23.127797811922814 1.0214215483502045 1.0758325248993732 0.3353221842112818 0.036245576286076255 258.2803890738114 142219.27949712137 0.011474923573258028 0.01481376579279069 6.033400575151464e-07 6.219437839642549 0.05441097654916871 FYEEVHDLER ddPTM_PC-9_Lapatinib_30min_R1 5 FYEEVHDLER 10 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;A8MXH2;E9PKT8;C9JZI7;E9PNW0;E9PJJ2;F8VVB5;P55209;F8W020;P55209-2;P55209-3;F8W0J6;H0YIV4;B7Z9C2;H0YHC3;F8VV59;F5H4R6;F8VY35;F8VUX1;F8VXI6;F8W118;F8VRJ2;F8W543;H0YH88 E9PNJ7;P55209 NAP1L4;NAP1L1 Nucleosome assembly protein 1-like 4;Nucleosome assembly protein 1-like 1 0 ;;;; 228.64 1.6249999999999998e-12 129830000.0 409575.4 391174.5 459664.9 387754.7 430074.1 411874.8 379735.9 381762.0 465858.4 327822.5 False True 403734.77968906966 390268.75947893894 421873.0262798265 416271.47414976027 404777.9869962134 394259.8749310534 399396.766839971 399500.0562106995 413388.52128556854 384486.1823289755 1.0500631706541397 1.0150397528330828 1.0972384591934747 1.0826695295738573 1.0527764211039337 1.025420140049962 1.0387805471205143 1.0390491897284302 1.0751713332882884 1.0 18.552572225956382 -6.533609472284775 20.553762960155094 1.03840493862943 1.0614222989106383 0.17091266076177003 0.026477312456823946 53.3432036904072 102167.40767492933 0.00901330710388406 0.009032780976877602 2.926783026373978e-07 6.533609472284775 0.023017360281208266 FYEQFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FYEQFSK 7 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 111.04 0.043202 21579000.0 110530.0 106900.0 101610.0 119990.0 149880.0 123150.0 115290.0 105250.0 106510.0 107090.0 False True 129240.5459329907 117512.32552251215 104032.7677580711 113267.34931282881 120512.08992258226 116691.79720681524 104368.89657268218 102487.29902159305 108067.50725287643 126504.56927602635 1.0216274927666416 0.9289176366911017 0.8223637166107182 0.8953617245688998 0.9526303327402443 0.9224314811285579 0.8250207654156326 0.8101470137254183 0.8542577384464176 1.0 16.9488299696553 -7.24331951391586 23.47744568404292 0.8565352991029708 0.9195123083215185 0.10383262504064816 0.0673607779882014 692.2618810615074 896947.0707804246 0.025990792603310886 0.02008002121132683 5.710583499017833e-08 7.24331951391586 0.06297700921854776 FYEQFSK ddPTM_PC-9_Lapatinib_30min_R1 1 FYEQFSK 7 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 116.73 0.035332 44223000.0 52534.0 45491.0 55384.0 46012.0 47591.0 39881.0 45848.0 42905.0 45558.0 42781.0 False True 51784.85552644432 45385.668384458724 50830.54130842252 49395.87597153242 44791.79094750599 38175.38259715168 48221.7851040131 44898.52293240315 40426.778292991876 50175.638847900686 1.032071672937174 0.9045359347000647 1.0130521997439248 0.9844593333682907 0.8926999630893598 0.7608350082571775 0.9610597136628319 0.8948271305225579 0.805705302837082 1.0 15.614699459982997 -6.2986379723725126 5.517840616147241 0.8774100983982824 0.9801772924216008 0.30774226016626727 0.07120073155529343 0.23514667140033643 19.83576739538072 0.021533616226350773 0.025014961661879893 5.027615165972265e-07 6.2986379723725126 0.10276719402331835 FYEQMNGPVAGASR ddPTM_PC-9_Lapatinib_30min_R1 1 FYEQMNGPVAGASR 14 0 P29692-2;P29692;E9PRY8;A0A087X1X7;E9PK01;P29692-3;E9PI39;E9PQ49;P29692-4;E9PL71;E9PL12;E9PQZ1;E9PPR1;H0YCK7;E9PK06;E9PIZ1;E9PMW7;E9PN91;E9PK72;E9PKK3 P29692-2 EEF1D Elongation factor 1-delta 0 98.368 0.032989 4459300.0 14648.0 12370.0 17946.0 15971.0 15328.0 20075.0 12960.0 10674.0 9366.8 11454.0 False True 14439.116833885786 12341.358025010535 16470.549153563305 17145.560617694184 14426.437176007468 19216.439047110656 13631.005386232988 11169.953007352784 8311.812347223231 13433.808638504353 1.0748341905436996 0.9186790103319913 1.2260520896773057 1.2762993041713504 1.073890328812487 1.4304535343783271 1.0146791392549261 0.8314807295480714 0.6187234440276069 1.0 13.713580762863087 -7.649924028324661 3.6079720129003077 0.7907104524422272 1.162669279904199 0.5001767819556036 0.15533648155952523 0.1891140825160675 4.707654177329274 0.08269714377051793 0.043834216663098065 2.2391127951045585e-08 7.649924028324661 0.37195882746197195 FYFHDGVR ddPTM_PC-9_AZD4547_30min_R2 2 FYFHDGVR 8 0 H0Y8C6;O00410-2;O00410;O00410-3 H0Y8C6 IPO5 Importin-5 0 ; 101.6 0.003807 8438300.0 51397.0 51697.0 67932.0 91840.0 74742.0 66895.0 63410.0 79538.0 64306.0 77593.0 False True 67740.17687598756 68407.044260065 67031.17729401974 70667.70691385547 64365.363440831024 62712.045075039205 69053.36715855314 67247.22970141219 67705.08387669903 74876.49268747117 0.9046921729992075 0.9135984045832761 0.8952232521600981 0.9437902922191768 0.8596204380123305 0.8375398315836527 0.9222302578564502 0.8981087025816907 0.9042234945391332 1.0 16.192225238336974 -9.346742622072705 1.2041477762650041 1.0002384999306815 0.8961232077357985 0.5397504751860669 0.02843707909522091 5.628707732345286 7.442708720939164 0.03180514688008715 0.008711421372157755 4.500464889885685e-10 9.346742622072705 -0.10411529219488302 FYFHDGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FYFHDGVR 8 0 H0Y8C6;O00410-2;O00410;O00410-3 H0Y8C6 IPO5 Importin-5 0 ; 113.41 0.0018937000000000001 0.0 42358.0 44287.0 52514.0 59712.0 57634.0 50320.0 58239.0 53273.0 48192.0 41317.0 False True 49528.37279136529 48683.52067741346 53766.132920454016 56366.530228915995 46341.03142913077 47681.13061670273 52722.18030615356 51874.64019740923 48896.71682969329 48807.445034807955 1.0147708562913547 0.9974609538092781 1.1015969568189787 1.1548756585950593 0.9494664470980152 0.9769233071450067 1.080207748398912 1.0628427724584608 1.0018290610135743 1.0 15.574813611262842 -6.279598776999247 24.980775121543953 1.0166891012788948 1.0646551026492734 0.1968499732528053 0.05410386093729001 1781.124637889739 2450176.8828143063 0.018509863874545358 0.02102415962689121 5.252925277049756e-07 6.279598776999247 0.04796600137037865 FYFHDGVR ddPTM_PC-9_Lapatinib_30min_R1 1 FYFHDGVR 8 0 H0Y8C6;O00410-2;O00410;O00410-3 H0Y8C6 IPO5 Importin-5 0 101.6 0.003807 2520300.0 23257.0 19033.0 19685.0 17324.0 23253.0 22791.0 18478.0 20290.0 20437.0 16684.0 False True 22925.35091518855 18988.93025788403 18066.575286297437 18598.06475116986 21885.304257156942 21816.282058415894 19434.700426451614 21232.747472286675 18135.16984884927 19567.807169967393 1.1715850793120193 0.9704168736407102 0.9232805254758417 0.9504419473079287 1.1184341744100195 1.1149068400418138 0.9931976668433206 1.085085686293691 0.926786005776011 1.0 14.256194471627218 -4.751645816983111 24.821230128072123 1.0135311255685595 1.171585428257895 0.32700217469249315 0.0696471537789104 492.96651444659227 1249300.96225003 0.01855012008106903 0.23866287796970836 1.7715531356532934e-05 4.751645816983111 0.1580543026893355 FYHDAK ddPTM_PC-9_AZD4547_30min_R2 2 FYHDAK 6 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 ; 101.52 0.015352000000000001 3295000.0 118515.0 87907.0 124909.0 137168.0 143890.0 126818.0 126331.0 129763.0 141529.0 164275.0 False True 156200.30473486165 116321.21863492145 123252.6250459092 105546.03682447443 123913.35722219368 118888.05041223278 137574.214264425 109711.11000709534 149009.9340028199 158523.7822514188 0.9853430350729828 0.7337777145036568 0.7775024245285195 0.6658056937922309 0.7816704563966751 0.7499698072032893 0.8678458986439791 0.6920798157155591 0.9399847258658646 1.0 17.274339768822728 -8.42977944618041 5.068979692553587 0.9984807359585892 0.7784525089290047 0.4399369306868114 0.08603804626599305 0.17608162247153997 6.705630365121997 0.07951573834367394 0.02069524467610092 3.717239589293168e-09 8.42977944618041 -0.22002822702958447 FYHDAK ddPTM_PC-9_Lapatinib_30min_R1 2 FYHDAK 6 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 ; 101.52 0.016903 3694600.0 140918.0 121623.0 121340.0 113694.0 125969.0 104401.0 119092.0 131411.0 146383.0 115340.0 False True 138908.48347880362 121341.3894159947 111363.89358594533 122055.43603206553 118559.7510845827 99936.01260061757 125258.00103836879 137516.834799441 129895.80505867297 135276.36531911063 1.0268496137601346 0.8969888356310877 0.8232324495357567 0.9022672640866899 0.8764262020561078 0.7387544185185134 0.9259415031065553 1.0165621649801517 0.9602254226172829 1.0 17.045550276682476 -7.527762764855792 13.736412845317524 0.9873079600832945 0.8732165731789943 0.3570218934188074 0.06881230240791261 0.6423526227724494 1777.9882004696292 0.03278364135900098 0.019341016885882266 2.9664513832700447e-08 7.527762764855792 -0.11409138690430021 FYQGLPWGVS(ph)SLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 FYQGLPWGVSSLPR 14 0 Q5JTC6 Q5JTC6 AMER1 APC membrane recruitment protein 1 1 FYQGLPWGVS(0.688)S(0.312)LPR 189.1 3.1189999999999997e-06 12587000.0 12067.0 11928.0 13274.0 17928.0 21217.0 17757.0 17036.0 18431.0 16023.0 16473.0 True False 14109.704765886141 13112.133010594254 13590.502501925328 16923.552283360226 17059.681157508898 16825.79166058804 15422.22675004089 17947.205779258733 16257.30606246214 19459.42449980376 0.7250833531088461 0.673819156919388 0.6984020777213829 0.8696841103153329 0.8766796344712525 0.8646602915085037 0.7925325206917818 0.9222886205827784 0.8354463957876085 1.0 14.248181423504219 -2.366238672352476 0.1588237702137223 0.999260193013656 7.053474603439236e-16 0.6836994303180106 0.05520535001798712 30.25546090964965 0.3958860710926608 0.18748339025037353 6.712017462293 0.004302900738253625 2.366238672352476 -0.9992601930136553 FYQGLPWGVS(ph)SLPR ddPTM_PC-9_Lapatinib_30min_R1 1 FYQGLPWGVSSLPR 14 0 Q5JTC6 Q5JTC6 AMER1 APC membrane recruitment protein 1 1 FYQGLPWGVS(0.716)S(0.284)LPR 168.67 0.00034192 6577300.0 51114.0 33621.0 52148.0 36587.0 37270.0 30228.0 23732.0 30829.0 38759.0 28723.0 True False 50385.10498684041 33543.15264016807 47860.59273710128 39277.73003065413 35077.85187563924 28935.218904909645 24960.726838432187 32261.427886797734 34393.55326963591 33687.73227900824 1.4956514308989792 0.9957082406840942 1.4207128084701783 1.1659357093362195 1.0412648611998505 0.8589245089358533 0.7409441108027894 0.9576610149832117 1.0209518700986437 1.0 15.039935694920878 -6.3206847529274235 2.277108430694028 0.9047359526203929 1.2734857182264763 0.5747434888337603 0.14471754111559604 0.2234976346882069 2.274754145629757 0.04794136055752384 0.05888907412429451 4.778760299767558e-07 6.3206847529274235 0.3687497656060834 FYQGLPWGVSS(ph)LPR ddPTM_PC-9_AZD4547_30min_R2 2 FYQGLPWGVSSLPR 14 0 Q5JTC6 Q5JTC6 AMER1 APC membrane recruitment protein 1 1 FYQGLPWGVS(0.068)S(0.932)LPR;FYQGLPWGVS(0.255)S(0.745)LPR 151.38 0.00021568 15541800.0 43499.0 41845.0 53035.0 75217.0 69680.0 58237.0 49319.0 69951.0 59213.0 55927.0 True False 57330.77716459294 55370.57792642552 52331.721247546586 57876.882741065645 60006.13476435077 54595.43118372162 53708.29545643719 59141.68026406861 62342.878294264665 53969.01275285391 1.0622906412450774 1.0259698130849633 0.9696623780611822 1.0724095140688874 1.1118627468533342 1.0116070018500494 0.9951691297817389 1.0958451386706378 1.1551606211467698 1.0 15.719843676094966 -6.598246363853972 0.6446986656529832 1.0708364484786528 1.0273137761047897 0.04290594860119157 0.05504063480162302 2.6756497897400333 2.4623622900668494 0.043816773373348133 0.0559769559362378 2.5220496740616364e-07 6.598246363853972 -0.04352267237386309 FYQGLPWGVSS(ph)LPR ddPTM_PC-9_Lapatinib_30min_R1 1 FYQGLPWGVSSLPR 14 0 Q5JTC6 Q5JTC6 AMER1 APC membrane recruitment protein 1 1 FYQGLPWGVS(0.059)S(0.941)LPR 162.64 0.00055067 4062700.0 36398.0 34880.0 38926.0 33138.0 31696.0 28510.0 21436.0 27893.0 38571.0 23379.0 True False 35878.9578454243 34799.23750302081 35725.65453870531 35575.07906512737 29831.703596733605 27290.693760056038 22545.851192846472 29189.010608402776 34226.72780936364 27420.02899944065 1.30849452588676 1.2691174580351718 1.3029036015765736 1.297412160499651 1.0879530286908943 0.9952831837126339 0.8222402388161731 1.064514213642816 1.2482382060960564 1.0 14.742942476462616 -6.357005087791334 3.3306464169468617 1.0188828695211334 1.2950341270228545 0.6289234645479862 0.09784815908715465 0.17676417557910348 3.729653176275696 0.034156128255923936 0.03972176160878306 4.3953646620610246e-07 6.357005087791334 0.2761512575017211 FYVHNDIFR ddPTM_PC-9_AZD4547_30min_R2 2 FYVHNDIFR 9 0 Q13283;E5RIZ6 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 0 ; 161.27 0.00012691 17259900.0 76515.0 68434.0 97418.0 134959.0 103963.0 91184.0 81890.0 107752.0 83334.0 90587.0 False True 100845.17838913124 90553.95220019117 96126.17366820952 103846.28764576477 89529.53198200618 85482.25006536164 89178.05135804956 91101.40429463396 87738.8651102671 87415.57670253678 1.1536293895571215 1.035901787942598 1.0996458216516 1.1879609054017848 1.0241828214056508 0.9778834995992307 1.020162020568831 1.0421644257366116 1.0036982929121478 1.0 16.415602758007445 -6.423101232368701 8.389885934562983 1.0109206861414064 1.1117391748886045 0.6385961112869811 0.03973813260693695 0.22636507289136232 17.272445316279207 0.01257982337864938 0.014254741775869068 3.7748419056064086e-07 6.423101232368701 0.10081848874719812 FYVHNDIFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 FYVHNDIFR 9 0 Q13283;E5RIZ6 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 0 ; 156.35 7.443e-05 14368800.0 88400.0 97316.0 116002.0 120804.0 133701.0 115145.0 122730.0 112820.0 114007.0 90741.0 False True 103364.37402041414 106976.88934096141 118767.92762003494 114035.74353185215 107503.24883065914 109106.59349881226 111104.12591174683 109858.59454267123 115674.136694946 107191.62499463941 0.9642952425208903 0.9979967123953132 1.1079963348440185 1.063849377575487 1.0029071658913213 1.0178649078626116 1.0365000616167828 1.0248803910582118 1.0791340900068527 1.0 16.709832665207294 -5.010259783755682 23.1900130082109 1.0417130677881699 0.9727205077221205 0.37739308106126657 0.03237272450334724 186.3823877850714 421297.7443816255 0.008384532954185496 0.026235383933140122 9.766528376587247e-06 5.010259783755682 -0.06899256006604937 FYVHNDIFR ddPTM_PC-9_Lapatinib_30min_R1 2 FYVHNDIFR 9 0 Q13283;E5RIZ6 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 0 ; 148.52 0.00026986 12633800.0 86119.0 72030.0 87500.0 81105.0 83141.0 78111.0 70942.0 71679.0 90572.0 69266.0 False True 84890.92726770943 71863.21896051007 80306.0877597676 87069.73225834857 78250.80984149511 74770.37461563441 74615.02963812802 75009.46801705437 80370.82759455776 81238.53580885658 1.044958853855348 0.8845952015875154 0.9885220968127378 1.07177869949813 0.9632227989141607 0.9203806281240606 0.9184684201311458 0.9233237314067504 0.9893190072216415 1.0 16.309876617209888 -6.5161137203628545 24.47628304441019 0.9433261558848172 0.9923552075774257 0.14441409309670938 0.05251086986209855 461.7663132661488 1670707.2208725302 0.017328672747491152 0.017977472688342776 3.047097000330841e-07 6.5161137203628545 0.049029051692608516 GAAAADLLS(ph)SSPESQHGGTQSPGGGQPLLQPTKVDAAEGR ddPTM_PC-9_AZD4547_30min_R2 1 GAAAADLLSSSPESQHGGTQSPGGGQPLLQPTKVDAAEGR 40 1 Q9H3S7 Q9H3S7 PTPN23 Tyrosine-protein phosphatase non-receptor type 23 1 GAAAADLLS(0.254)S(0.226)S(0.226)PES(0.254)QHGGT(0.019)QS(0.019)PGGGQPLLQPTKVDAAEGR 75.384 7.9999e-10 10179000.0 7395.4 7159.4 16431.0 53836.0 33244.0 24032.0 13031.0 22494.0 16874.0 21009.0 True False 9746.983366124066 9473.536040302324 16213.114204175325 41424.94195790859 28628.644433210073 22529.27524094989 14190.733755608038 19018.069160697643 17765.925191046255 20273.481304641926 0.4807750193299236 0.467287087893149 0.7997202828930561 2.0433067875927016 1.412122762885085 1.1112682080798557 0.6999653163839626 0.9380761436538856 0.8763134917029999 1.0 14.307306225122721 -5.527062256634905 24.99914073517442 1.1633698987532028 0.5138990369771341 0.38249796148871584 0.3488185149855195 127.4802012488114 761772.8775830376 0.1056243309584652 0.18392717930037455 2.971240070379709e-06 5.527062256634905 -0.6494708617760687 GAAAADLLSS(ph)SPESQHGGTQSPGGGQPLLQPTK ddPTM_PC-9_AZD4547_30min_R2 2 GAAAADLLSSSPESQHGGTQSPGGGQPLLQPTK 33 0 Q9H3S7 Q9H3S7 PTPN23 Tyrosine-protein phosphatase non-receptor type 23 1 GAAAADLLS(0.039)S(0.314)S(0.314)PES(0.314)QHGGT(0.015)QS(0.005)PGGGQPLLQPTK;GAAAADLLS(0.065)S(0.314)S(0.278)PES(0.278)QHGGT(0.025)QS(0.04)PGGGQPLLQPTK 90.12700000000001 5.265e-12 36098000.0 29359.0 24297.0 169628.0 240616.0 184623.0 189873.0 99378.0 235940.0 127223.0 179068.0 True False 38694.55129486388 32150.530096268645 167378.62188703378 185145.6986801423 158991.28327495343 178000.21129431075 108222.44947930421 199480.89436183 133947.74804909766 172798.88382405727 0.2239282479061753 0.18605751023834224 0.9686325408065577 1.0714519363947772 0.9200943880912874 1.0301004691416262 0.6262913688117084 1.1544107805982138 0.7751655860548405 1.0 17.39873437303369 -5.26118638428636 24.99984539901724 0.944313948088017 0.2049928095871971 0.8116211985322407 0.14227074048883215 7.9199464722347255 782510.5524725235 0.03488644628150532 0.08134257784407443 5.4804171374921125e-06 5.26118638428636 -0.7393211385008199 GAAAADLLSS(ph)SPESQHGGTQSPGGGQPLLQPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GAAAADLLSSSPESQHGGTQSPGGGQPLLQPTK 33 0 Q9H3S7 Q9H3S7 PTPN23 Tyrosine-protein phosphatase non-receptor type 23 1 GAAAADLLS(0.09)S(0.445)S(0.391)PES(0.07)QHGGT(0.003)QS(0.002)PGGGQPLLQPTK;GAAAADLLS(0.075)S(0.287)S(0.287)PES(0.235)QHGGT(0.06)QS(0.057)PGGGQPLLQPTK 90.51799999999999 4.7129e-12 30694000.0 34199.0 54328.0 146991.0 134840.0 173954.0 160077.0 127810.0 112963.0 130719.0 92646.0 True False 39988.21523896082 59721.32479875623 150495.822906472 127285.35195717821 139868.96243923757 151682.28032054676 115702.91153573184 109997.84094419201 132630.51807894857 109441.98641466758 0.36538276167108696 0.5456893351010329 1.3751196212416545 1.1630394890211828 1.2780192229816116 1.385960592362001 1.0572077072627508 1.0050789879436064 1.2118796672459997 1.0 16.739806795487645 -5.162957399212479 4.88339122062314 1.1890373859026406 0.4138268980101276 0.8285241953364364 0.13327725506067487 0.08326727098428816 3.149034755776781 0.03545653300060016 0.10095407266651142 6.871358391948596e-06 5.162957399212479 -0.775210487892513 down GAAAADLLSS(ph)SPESQHGGTQSPGGGQPLLQPTK ddPTM_PC-9_Lapatinib_30min_R1 1 GAAAADLLSSSPESQHGGTQSPGGGQPLLQPTK 33 0 Q9H3S7 Q9H3S7 PTPN23 Tyrosine-protein phosphatase non-receptor type 23 1 GAAAADLLS(0.061)S(0.302)S(0.302)PES(0.302)QHGGT(0.013)QS(0.021)PGGGQPLLQPTK 86.304 1.0664e-11 9104800.0 19265.0 15828.0 54506.0 22740.0 35288.0 43031.0 27709.0 34508.0 57865.0 25235.0 True False 18990.277567231682 15791.351238469431 50024.72707924447 24412.375458416227 33212.42921887733 41190.664440160304 29143.636438821726 36111.36765764757 51347.634354536516 29596.836126476122 0.6416320138436606 0.5335486256364792 1.6902052255002482 0.8248305783123188 1.1221614728327953 1.3917252595561327 0.9846875630314761 1.2201090516341986 1.7349028164737859 1.0 14.853155340923783 -5.235494608047652 24.899009625157866 1.2303350060046878 0.5875900814357384 0.46761895556448296 0.2806410624694304 621.0617124641639 596026.2466236799 0.06904993044220815 0.18255147194040197 5.814406510988132e-06 5.235494608047652 -0.6427449245689494 GAAAADLLSS(ph)SPESQHGGTQSPGGGQPLLQPTKVDAAEGR ddPTM_PC-9_AZD4547_30min_R2 1 GAAAADLLSSSPESQHGGTQSPGGGQPLLQPTKVDAAEGR 40 1 Q9H3S7 Q9H3S7 PTPN23 Tyrosine-protein phosphatase non-receptor type 23 1 GAAAADLLS(0.115)S(0.425)S(0.425)PES(0.029)QHGGT(0.003)QS(0.003)PGGGQPLLQPTKVDAAEGR 75.89699999999999 7.519199999999999e-10 9356600.0 17051.0 15215.0 37723.0 79433.0 57687.0 33851.0 24159.0 41496.0 28632.0 42220.0 True False 22472.863317167627 20132.95120445847 37222.76837222965 61120.94907761642 49678.15580010192 31734.29161873314 26309.104197815563 35083.74668321814 30145.42906661348 40741.89065076784 0.5515910763641523 0.4941584909997061 0.9136239820409054 1.5001991341426495 1.219338499185866 0.7789106276572626 0.645750694864224 0.8611222042675856 0.7399123748334282 1.0 15.314225310496283 -5.29099186564201 6.107165315826121 0.9650529125766094 0.5214499862979689 0.35330574260507874 0.23531056127209207 0.20520958620054733 26.263467294700604 0.07062632791886785 0.1562424572514533 5.1169141945716665e-06 5.29099186564201 -0.4436029262786405 GAAAADLLSSS(ph)PESQHGGTQSPGGGQPLLQPTK ddPTM_PC-9_Lapatinib_30min_R1 1 GAAAADLLSSSPESQHGGTQSPGGGQPLLQPTK 33 0 Q9H3S7 Q9H3S7 PTPN23 Tyrosine-protein phosphatase non-receptor type 23 1 GAAAADLLS(0.029)S(0.101)S(0.427)PES(0.427)QHGGT(0.013)QS(0.003)PGGGQPLLQPTK 94.152 1.0604e-15 8970400.0 24425.0 24503.0 83618.0 33706.0 61665.0 76444.0 35894.0 47854.0 99203.0 35893.0 True False 24076.695021003572 24446.26480895982 76743.2508148141 36184.85167991983 58037.98593805459 73174.6683196676 37752.41568930916 50077.47153961589 88029.71348609836 42097.05722558378 0.5719329712759913 0.5807119646858121 1.8230074944092451 0.8595577473745384 1.37867085642231 1.7382371391793372 0.8967946497306647 1.189571785772763 2.0911132342191316 1.0 15.361431765467154 -5.235429837335605 23.289743344478925 1.3569174958481356 0.576321593227106 0.40007183576230265 0.38944502132732595 316.1211338524801 283061.3115198349 0.09570145808119375 0.25293096807432713 5.815273736684651e-06 5.235429837335605 -0.7805959026210296 GAAAADLLSSSPES(ph)QHGGTQSPGGGQPLLQPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GAAAADLLSSSPESQHGGTQSPGGGQPLLQPTK 33 0 Q9H3S7 Q9H3S7 PTPN23 Tyrosine-protein phosphatase non-receptor type 23 1 GAAAADLLS(0.051)S(0.207)S(0.207)PES(0.449)QHGGT(0.063)QS(0.023)PGGGQPLLQPTK 64.383 2.324e-05 7227000.0 4406.1 7053.5 18951.0 17288.0 20953.0 18524.0 16843.0 13533.0 15146.0 8371.5 True False 5151.965705558209 7753.724865042465 19402.86371206773 16319.409408452237 16847.41006236903 17552.56883036171 15247.509107239894 13177.773089398746 15367.481596583135 9889.186681242469 0.5209696076756558 0.7840609258342258 1.9620282574774868 1.6502276612298596 1.703619377953975 1.774925420677408 1.5418365128207094 1.3325436675590294 1.5539681969733408 1.0 13.2716361586103 -5.126309747649838 5.142595285695713 1.5893291103373421 0.5838200062390511 0.6860428941800314 0.24860741953674353 0.11094556736433964 4.082200601289767 0.06239325194956564 0.1775835613840463 7.4763608106516335e-06 5.126309747649838 -1.005509104098291 GAAAADLLSSSPES(ph)QHGGTQSPGGGQPLLQPTK ddPTM_PC-9_Lapatinib_30min_R1 1 GAAAADLLSSSPESQHGGTQSPGGGQPLLQPTK 33 0 Q9H3S7 Q9H3S7 PTPN23 Tyrosine-protein phosphatase non-receptor type 23 1 GAAAADLLS(0.081)S(0.281)S(0.281)PES(0.323)QHGGT(0.019)QS(0.016)PGGGQPLLQPTK 71.903 5.1244000000000004e-06 8027600.0 27992.0 27012.0 109730.0 41063.0 71859.0 99933.0 54139.0 69818.0 121120.0 48184.0 True False 27592.828946895897 26949.455373612334 100708.42297004905 44082.9100021524 67632.39490022973 95659.09854520083 56942.05251583856 73061.99916313989 107478.19014985666 56512.54019885576 0.4882602843510932 0.47687566828146216 1.7820544363370903 0.7800553619963622 1.196767914913142 1.6927056934371834 1.0076003010211794 1.2928457808842084 1.9018467365236722 1.0 15.786283418320986 -5.238996400795295 23.756264949643455 1.3189858263174452 0.4825673935331849 0.49016704268006206 0.34621818983168284 348.1513083494833 368520.8189890337 0.08551332518419569 0.22577636103078008 5.767712433497618e-06 5.238996400795295 -0.8364184327842603 GAAAADLLSSSPESQHGGTQS(ph)PGGGQPLLQPTK ddPTM_PC-9_AZD4547_30min_R2 2 GAAAADLLSSSPESQHGGTQSPGGGQPLLQPTK 33 0 Q9H3S7 Q9H3S7 PTPN23 Tyrosine-protein phosphatase non-receptor type 23 1 GAAAADLLS(0.01)S(0.029)S(0.029)PES(0.029)QHGGT(0.086)QS(0.806)PGGGQPLLQPT(0.009)K;GAAAADLLS(0.014)S(0.046)S(0.046)PES(0.046)QHGGT(0.044)QS(0.804)PGGGQPLLQPTK 71.67 5.6861000000000005e-06 37807000.0 21136.7 24435.0 196765.0 298100.0 229545.0 211817.0 109089.0 280740.0 134973.0 210499.0 True False 27857.730929328296 32333.13589753153 194155.76753603297 229377.65059908878 197676.6389851161 198572.04950533767 118797.70966660454 237358.08376341467 142107.39722715915 203129.49408090863 0.13714271802514444 0.1591749934879122 0.9558226313442137 1.129218834699235 0.973155768833744 0.9775638461751119 0.5848373236202034 1.1685062518241316 0.6995901696607203 1.0 17.632040206315814 -5.2601322443588385 23.17140218898007 0.939263131066652 0.14815859389529706 0.7809990952584507 0.1668885600487085 16.611547538273197 294443.4934018638 0.041957196065286056 0.09913347318463864 5.493735619990575e-06 5.2601322443588385 -0.791104537171355 GAAAHPDSEEQQQR ddPTM_PC-9_AZD4547_30min_R2 2 GAAAHPDSEEQQQR 14 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 ; 139.89 9.212100000000001e-05 2468000.0 9465.5 9608.4 13254.3 23509.0 19316.1 12634.0 13423.3 20126.3 10660.9 13745.1 False True 12475.33210536919 12714.127397497112 13078.53932179423 18089.363260429323 16634.392935156084 11843.993982779666 14617.94769562224 17016.2427913643 11224.413409341292 13263.888232682824 0.9405486450518638 0.9585520606370102 0.9860260500060694 1.3638054651166547 1.254111361868097 0.8929503758630539 1.10208616351297 1.2829000435509932 0.8462385397431069 1.0 13.695216134768248 -5.548367679176822 24.99438772392213 1.1195444486429014 0.9552347334602378 0.14993722953681132 0.15662697568660025 370.2339338391025 363048.7679150757 0.04295162434936015 0.07439756211639169 2.8289959181019978e-06 5.548367679176822 -0.16430971518266357 GAAAHPDSEEQQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GAAAHPDSEEQQQR 14 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 ; 163.45 1.3884000000000002e-13 410940.0 8649.7 8813.7 9824.3 11362.4 10991.5 10287.0 9982.5 9090.9 8756.7 7469.5 False True 10113.923370637724 9688.665888285932 10058.548570865223 10725.80156539783 8837.794478142945 9747.531610771475 9036.885332958633 8852.273507604747 8884.750171451184 8823.661221470533 1.146227525828803 1.0980323977886404 1.1399518089372982 1.2155726853269067 1.0016017451619768 1.1047037466775014 1.024165038314171 1.0032426773213585 1.006923310907722 1.0 13.107161685350336 -6.812452449958529 1.0342790389567085 1.0039769404820376 1.141540605768255 0.6048420950414994 0.046123637650635145 0.36487296294992705 0.8308504219459969 0.02650610366221889 0.022853201302034595 1.5400951387910058e-07 6.812452449958529 0.13756366528621733 GAAAHPDSEEQQQR ddPTM_PC-9_Lapatinib_30min_R1 3 GAAAHPDSEEQQQR 14 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 ;; 180.24 1.6009000000000002e-05 3463160.0 25210.199999999997 23510.9 30175.0 24983.199999999997 25537.699999999997 26323.3 21811.2 23071.300000000003 24518.7 19329.800000000003 False True 24850.69792501553 23456.46195555539 27694.127978868415 26820.547869512047 24035.62269504998 25197.51382160936 22940.47721297876 24143.276823921526 21757.145812642786 22670.9301746605 1.096148139205659 1.0346492964709884 1.2215699914166904 1.1830369403849874 1.0601957003914557 1.1114459630674016 1.0118895447271736 1.0649442540697638 0.959693565505351 1.0 14.46855596475429 -7.308740520190287 1.107615856772407 0.9960473477121012 1.1275411875290404 0.4840885153893596 0.05553397623679911 0.4862528478102732 1.1498154523895872 0.04153475088239335 0.022685706637681276 4.9120126865129865e-08 7.308740520190287 0.13149383981693918 GAADEVEVEPPEPPGPVAS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 GAADEVEVEPPEPPGPVASR 20 0 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 GAADEVEVEPPEPPGPVAS(1)R;GAADEVEVEPPEPPGPVAS(1)R 215.06 2.2572999999999997e-28 5512600.0 18475.2 25221.0 23658.6 15667.7 19042.8 26993.8 28739.6 33815.0 27382.0 16628.8 True False 24349.929291967335 33373.195026463814 23344.871505745374 12055.75382855199 16399.0359226547 25305.87341873971 31297.368724017546 28589.66874139728 28829.356618539074 16046.630773412791 1.5174480946063795 2.079763378226345 1.4548145237082934 0.7512950225368696 1.02196131725208 1.5770209819165464 1.950401250328092 1.7816617796657161 1.7965987393631329 1.0 13.969982793610544 -6.991557225957945 24.508677250134753 1.7067907103353361 1.368035080879987 0.08216825762985369 0.40113810609050876 342.4335396904833 994049.2023217493 0.1532236264871346 0.13490306636792143 1.0196303969038309e-07 6.991557225957945 -0.3387556294553491 GAADEVEVEPPEPPGPVAS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GAADEVEVEPPEPPGPVASR 20 0 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 GAADEVEVEPPEPPGPVAS(1)R;GAADEVEVEPPEPPGPVAS(1)R 283.64 1.4604999999999998e-106 7688700.0 22727.0 61761.0 37645.0 20721.0 25895.0 15307.8 17918.5 7094.6 12533.9 14225.0 True False 26574.232221288992 67892.2239157705 38542.5995694575 19560.0695483884 20821.06063881287 14505.03202015823 16221.129961294197 6908.374267350061 12717.184575690828 16803.879894961963 1.581434310849622 4.040270719628598 2.293672640508048 1.1640210279206282 1.2390626908167388 0.863195411466077 0.9653205130416052 0.411117807942753 0.756800492218682 1.0 14.036506758920105 -5.72180072308624 3.00656962326567 0.8742879851316442 2.8832808648091133 0.6487083762216628 0.589816067932246 0.13751360482471844 2.53040876629746 0.16170866930343022 0.2921895965701402 1.8975764283149536e-06 5.72180072308624 2.008992879677469 GAADEVEVEPPEPPGPVAS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 2 GAADEVEVEPPEPPGPVASR 20 0 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 GAADEVEVEPPEPPGPVAS(1)R;GAADEVEVEPPEPPGPVAS(1)R 230.67 2.2622e-36 6332400.0 21609.4 31507.0 23825.6 19153.8 21526.5 19950.5 19637.5 21092.3 19087.7 16280.5 True False 21301.24599332137 31434.04747728429 21866.751137475654 20562.43434720372 20260.353592727348 19097.263621886985 20654.233662974544 22072.325259226818 16937.84222360818 19094.56273259737 1.1155660536261902 1.6462302864690121 1.1451820837010178 1.0768738009433685 1.0610535510268477 1.0001414480827573 1.0816814164439899 1.1559481915522447 0.8870505421259354 1.0 14.220874262026951 -5.4814214750087515 9.536255795527332 1.050230917973911 1.385186757166847 0.49676269777371795 0.13619723112077606 0.3722729984011654 82.96449848260745 0.032918315754508716 0.06781700177905706 3.3004907884658783e-06 5.4814214750087515 0.3349558391929359 GAAEGPPKRPGGS(ph)SPLNAVPCEGPPGSEPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GAAEGPPKRPGGSSPLNAVPCEGPPGSEPPR 31 2 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 GAAEGPPKRPGGS(0.5)S(0.5)PLNAVPCEGPPGSEPPR 45.615 0.006280399999999999 9504400.0 24684.0 16244.0 24602.0 29831.0 28920.0 27708.0 26136.0 20925.0 26851.0 20658.0 True False 28862.51366877712 17856.59696714394 25188.604983604568 28159.66578340688 23253.333603957075 26254.94370285372 23660.20887174623 20375.74092187015 27243.645077898713 24403.131871361988 1.182738093656265 0.7317338225795249 1.0321873895688103 1.153936549285845 0.9528831678873873 1.0758841873761664 0.969556243701342 0.8349641771096548 1.1163995351707368 1.0 14.57477869312987 -10.268213897333993 18.130495862113534 0.9999999999945006 0.9971175005939134 0.0 0.13421922603656244 0.0 0.0 0.12472393431364051 0.030249997365749348 5.3924496988748015e-11 10.268213897333993 -0.0028824994005872684 GAAGGAS(ph)TPTPQHGEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GAAGGASTPTPQHGEEK 17 0 O60299-2;O60299 O60299-2 LZTS3 Leucine zipper putative tumor suppressor 3 1 GAAGGAS(0.499)T(0.499)PT(0.002)PQHGEEK 61.684 0.017766999999999998 4062600.0 20190.0 16812.0 20220.0 28912.0 27633.0 22887.0 22638.0 21097.0 16554.0 16184.0 True False 23607.76822932306 18480.98425336271 20702.121484777017 27292.15437396869 22218.512015150263 21686.76542973918 20493.564755073123 20543.22610411921 16796.070932908842 19118.031087526502 1.234843071508858 0.9666782195694078 1.0828584486550004 1.4275609370556661 1.1621757446375667 1.1343618665778108 1.0719495465432152 1.0745471649286402 0.8785460624063628 1.0 14.222646331397081 -7.758520080826925 1.4423339854028692 0.9489833414743758 1.167116706771301 0.3567285802769341 0.11593823903693072 0.5243839769595691 2.0265724021313467 0.09912141751458803 0.03858645042062305 1.7437327292144285e-08 7.758520080826925 0.21813336529692529 GAAGGAST(ph)PTPQHGEEK ddPTM_PC-9_AZD4547_30min_R2 1 GAAGGASTPTPQHGEEK 17 0 O60299-2;O60299 O60299-2 LZTS3 Leucine zipper putative tumor suppressor 3 1 GAAGGAS(0.252)T(0.694)PT(0.054)PQHGEEK 77.357 0.016214 3017500.0 8692.8 11997.0 13700.0 22476.0 18915.0 17226.0 16119.0 16429.0 15656.0 16890.0 True False 11456.929578527637 15874.795635878281 13518.329048579013 17294.50545073843 16288.978746666127 16148.855496862625 17553.55977335938 13890.27555086252 16483.544197642525 16298.686240915884 0.7029357709682391 0.9739923452251338 0.8294121899618437 1.0610981274872733 0.9994044002009569 0.9908071888839036 1.0769923117664102 0.8522328330974713 1.0113418930823135 1.0 13.992468059950513 -4.136156157064272 1.1364357941260623 0.9867186570471048 1.8814158786045663e-17 0.5324273107449036 0.0763140345021508 4.800311812892046 1.8307432548537084 0.022478875980536914 8.074740982264375 7.308762387689463e-05 4.136156157064272 -0.9867186570471048 GAAGGAST(ph)PTPQHGEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GAAGGASTPTPQHGEEK 17 0 O60299-2;O60299 O60299-2 LZTS3 Leucine zipper putative tumor suppressor 3 1 GAAGGAS(0.083)T(0.673)PT(0.244)PQHGEEK;GAAGGAS(0.187)T(0.768)PT(0.046)PQHGEEK 111.65 0.0059253 3856800.0 32327.0 41491.0 39142.0 47169.0 51528.0 44327.0 44627.0 30258.0 39004.0 36367.0 True False 37799.322612646174 45609.95227553372 40075.29372686163 44526.27385396131 41431.458296843 42002.41408677628 40399.60748849935 29463.75956100105 39574.35971168155 42960.049218986394 0.8798714922314518 1.0616829613727767 0.9328502749747821 1.0364577011304428 0.9644183153899221 0.9777087049568165 0.940399469343358 0.6858409172394384 0.9211898131204067 1.0 15.390708025757945 -7.539094687281538 24.995291782803008 0.8447332270567228 0.9780202618378756 0.21224210630241347 0.08801883137152311 272.69329634189825 420324.97362230805 0.03815150610710161 0.0220344331777015 2.890049709071825e-08 7.539094687281538 0.13328703478115278 GAAGWS(ph)PSSSGNPMAKPESR ddPTM_PC-9_AZD4547_30min_R2 1 GAAGWSPSSSGNPMAKPESR 20 1 Q8WY91 Q8WY91 THAP4 THAP domain-containing protein 4 1 GAAGWS(0.656)PS(0.223)S(0.093)S(0.028)GNPMAKPESR 59.547 0.023156 5873900.0 17504.0 13214.0 19483.0 26862.0 21489.0 20291.0 16784.0 20794.0 15947.0 20524.0 True False 23069.907894182288 17485.167086146186 19224.642690033947 20669.380913762914 18505.62327714028 19022.200562338297 18277.743485083676 17580.765098583917 16789.925863554257 19805.461007019414 1.164825594617863 0.8828457504699904 0.9706738299714601 1.0436202876791059 0.9343697311858357 0.9604522992722303 0.9228638242051378 0.8876726016300744 0.8477422392542947 1.0 14.273610662453182 -6.747005650551881 1.0338721224124616 0.9029753694557343 1.0058717679389455 0.23515004849417265 0.07647207391134003 0.7878118145667274 1.8036928294875512 0.04156067481175592 0.03828120025303878 1.7905825568351735e-07 6.747005650551881 0.1028963984832112 GAANAS(ph)GSSPDAPAKDAR ddPTM_PC-9_AZD4547_30min_R2 1 GAANASGSSPDAPAKDAR 18 1 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 GAANAS(0.426)GS(0.325)S(0.249)PDAPAKDAR 47.75 0.04129 2555500.0 5364.7 3851.2 7041.1 11619.0 9252.7 7902.4 6704.1 7053.6 6576.8 8131.9 True False 7070.563007308024 5096.025085679292 6947.730413426989 8940.41906176053 7968.122318227731 7408.261678765074 7300.751912437407 5963.628195603133 6924.436221196692 7847.204656157726 0.9010295152375988 0.6494064203716702 0.8853764770841146 1.1393125900883643 1.015409010898565 0.9440637785522502 0.9303633882810083 0.7599684801037341 0.8824080070045153 1.0 12.93796311103528 -5.513180782271035 24.963805441256646 0.9495795921288835 0.7732613111863773 0.3015668695833148 0.10742586779150382 554.2994139911951 1426836.098491189 0.030778861949683625 0.05760803780485524 3.0677447230181117e-06 5.513180782271035 -0.17631828094250623 GAANAS(ph)GSSPDAPAKDAR ddPTM_PC-9_Lapatinib_30min_R1 1 GAANASGSSPDAPAKDAR 18 1 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 GAANAS(0.674)GS(0.035)S(0.292)PDAPAKDAR 95.361 0.00042510000000000003 4029600.0 17452.0 9526.3 11780.0 10862.0 12463.0 10210.0 10310.0 9513.9 16065.0 8115.2 True False 17203.131279695157 9504.242437644127 10811.493872115003 11660.827714569796 11729.950843200753 9773.342100672464 10843.801352782566 9955.950526199524 14255.590528050274 9517.9015071757 1.807450021070867 0.9985649074513667 1.1359115099020558 1.2251469198098455 1.2324093535068998 1.0268379109937398 1.139305901054686 1.0460236974183408 1.4977661323037177 1.0 13.216427809990037 -4.753478752697752 24.99884096584045 1.147235441284985 1.8074512218965784 0.6586036605878722 0.14314621487836346 173.54360980283633 544937.5490096131 0.03394748789827817 0.3642878775169836 1.7640920683141566e-05 4.753478752697752 0.6602157806115934 GAANASGS(ph)SPDAPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GAANASGSSPDAPAK 15 0 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 GAANAS(0.111)GS(0.777)S(0.111)PDAPAK 111.07 0.00046052 8362000.0 96018.0 99917.0 98450.0 98193.0 96609.0 83110.0 99170.0 99055.0 79702.0 76056.0 True False 112271.95095805528 109836.09943155164 100797.42137370426 92691.56455600135 77679.15996350934 78751.56529320672 89775.89967137565 96454.91120744776 80867.49096862986 89844.35074103544 1.2496272724109774 1.2225153671391071 1.1219116231830715 1.0316905157807044 0.8645970428058336 0.8765333005766582 0.9992381149277033 1.0735779201684745 0.9000843158377293 1.0 16.45514017194219 -5.632722360176686 1.9276259136123621 0.9549181258221103 1.2390023949926927 0.7720826490974494 0.06134711772822342 0.17035095667569441 1.2695191887355135 0.02016136992940384 0.046680620654849306 2.3295800573744276e-06 5.632722360176686 0.2840842691705824 GAANASGS(ph)SPDAPAK ddPTM_PC-9_Lapatinib_30min_R1 1 GAANASGSSPDAPAK 15 0 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 GAANAS(0.034)GS(0.853)S(0.113)PDAPAK 135.86 2.6195e-05 24021000.0 110680.0 172110.0 173540.0 160370.0 187920.0 181150.0 162050.0 177870.0 166010.0 145880.0 True False 109101.68290377382 171711.48986940726 159272.21108377204 172164.1447786373 176866.915064935 173402.6367812749 170440.1560832603 186134.48954635943 147312.20563720062 171095.16362711872 0.6376666680160977 1.0036022423382567 0.9308983825567777 1.0062478747432528 1.0337341589058304 1.01348648965429 0.9961716770364947 1.087900356739581 0.8609957319322585 1.0 17.38443945396147 -4.760688329416786 24.999571488367522 0.9958609491956524 0.637666254006288 0.7753750205386833 0.05728010477442727 7.943414290797822 264232.514771466 0.013521880420434396 0.07889848120944068 1.7350487053704156e-05 4.760688329416786 -0.3581946951893644 GAANASGS(ph)SPDAPAKDAR ddPTM_PC-9_AZD4547_30min_R2 1 GAANASGSSPDAPAKDAR 18 1 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 GAANAS(0.181)GS(0.479)S(0.34)PDAPAKDAR 57.227 0.01645 3417600.0 8320.1 7333.6 9268.2 14131.0 12464.0 9495.7 6622.5 10378.0 7796.1 11895.0 True False 10965.71873116922 9704.042783635658 9145.297612265695 10873.316271773652 10733.588744300634 8901.932377891471 7211.889670517557 8774.318562715394 8208.185929946409 11478.55967055622 0.95532183879285 0.8454059622591504 0.7967286728250756 0.9472718340842811 0.9350989194082844 0.7755269505394405 0.6282922141370101 0.7644093696896916 0.7150884924178524 1.0 13.486654003574262 -6.860729201417174 6.058986805311042 0.7501935376787614 0.8900748972656534 0.24613816423691048 0.09956916787246126 0.2581332486029283 13.335350250107734 0.03416910612667244 0.030186292177634876 1.3780684774354716e-07 6.860729201417174 0.13988135958689196 GAANASGSS(ph)PDAPAK ddPTM_PC-9_AZD4547_30min_R2 3 GAANASGSSPDAPAK 15 0 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 GAANAS(0.003)GS(0.18)S(0.818)PDAPAK;GAANAS(0.008)GS(0.195)S(0.797)PDAPAK;GAANASGS(0.281)S(0.719)PDAPAK 192.23 4.8362999999999994e-08 33660900.0 89978.0 102085.0 120804.0 106001.0 104934.0 127153.0 128940.0 150931.0 106891.0 116803.0 True False 118589.13234133509 135081.97986902032 119202.06002806858 81564.10714912452 90365.72539268639 119202.10280927546 140415.41021012206 127608.08199934452 112541.04003769845 112713.76252206629 1.052126463422056 1.1984515186650337 1.0575643768854939 0.723639290571606 0.801727520851726 1.0575647564416895 1.2457698782136968 1.1321428647576406 0.9984676007569703 1.0 16.782304155963942 -6.99105410721532 24.94115427752103 1.1117584844071327 0.9669737413449703 0.15256147998038294 0.14115839997225307 374.2833765208894 1043496.0475801418 0.05619326893043289 0.049489912941700964 1.0208122963870293e-07 6.99105410721532 -0.14478474306216238 GAANASGSS(ph)PDAPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GAANASGSSPDAPAK 15 0 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 GAANAS(0.002)GS(0.056)S(0.942)PDAPAK;GAANASGS(0.129)S(0.871)PDAPAK;GAANAS(0.001)GS(0.177)S(0.823)PDAPAK;GAANAS(0.003)GS(0.188)S(0.809)PDAPAK 182.7 4.1376e-06 33502300.0 132962.0 168979.0 154021.0 135311.0 158911.0 119013.0 146450.0 107124.0 105155.0 98032.0 True False 155469.84048079484 185754.1183766939 157693.44476789495 127729.96335418113 127773.53030215843 112771.74876958755 132577.1957938182 104312.1085072602 106692.69294128503 115804.4255791149 1.3425207171774403 1.6040329844716597 1.3617220929105376 1.1029799829793119 1.1033561944043884 0.9738120819272532 1.1448370399561674 0.9007609854771619 0.921317923798992 1.0 16.821330862816126 -5.7766101813120825 2.0430886803277213 1.0072362156791907 1.4833827903622998 0.8182852129513606 0.091447571342201 0.12532453784183012 1.068026598199748 0.02799266618215292 0.0539859163181133 1.672591243079047e-06 5.7766101813120825 0.47614657468310906 GAANASGSS(ph)PDAPAK ddPTM_PC-9_Lapatinib_30min_R1 4 GAANASGSSPDAPAK 15 0 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 GAANAS(0.001)GS(0.101)S(0.898)PDAPAK;GAANAS(0.012)GS(0.101)S(0.888)PDAPAK;GAANAS(0.062)GS(0.332)S(0.606)PDAPAK;GAANAS(0.01)GS(0.281)S(0.709)PDAPAK 204.9 8.2661e-13 45834800.0 61349.3 121605.0 111204.0 102980.0 127196.0 113665.0 121537.0 117583.0 109613.0 95174.0 True False 60474.447731916254 121323.43109388914 102061.23637985386 110553.49273120961 119714.58135695763 108803.81291605634 127829.59117489182 123046.3354378452 97267.22966393856 111624.69908861624 0.5417658298358055 1.0868869711135642 0.9143248511588804 0.9904035006037847 1.0724739446949731 0.9747288351449847 1.1451729968240352 1.102321766082985 0.8713773067976683 1.0 16.768296760655012 -4.756633352059148 24.999340012340333 1.0210155261940816 0.5417651017373166 0.7543285083256788 0.08143006407099411 71.09587208406846 369773.3991188342 0.020093893511126646 0.15970828797436964 1.7513245996051616e-05 4.756633352059148 -0.479250424456765 GAANASGSS(ph)PDAPAKDAR ddPTM_PC-9_AZD4547_30min_R2 2 GAANASGSSPDAPAKDAR 18 1 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 GAANAS(0.007)GS(0.064)S(0.93)PDAPAKDAR;GAANAS(0.021)GS(0.102)S(0.877)PDAPAKDAR 102.47 0.002231 9840900.0 36646.0 24957.0 59386.0 76985.0 65203.0 55641.0 33903.0 54625.0 43920.5 52748.0 True False 48298.66571584802 33023.86218926517 58598.50283787689 59237.29765639333 56150.68893570555 52161.75947410508 36920.30132118633 46183.96140762465 46242.047964522164 50901.308575241645 0.9488688418383895 0.6487821848518832 1.1512180035854551 1.1637676773835695 1.1031285934958692 1.0247626423395433 0.725331083907425 0.9073236563133957 0.908464816698529 1.0 15.635415125256014 GAANASGSS(ph)PDAPAKDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GAANASGSSPDAPAKDAR 18 1 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 GAANAS(0.13)GS(0.244)S(0.626)PDAPAKDAR;GAANAS(0.02)GS(0.282)S(0.698)PDAPAKDAR;GAANAS(0.057)GS(0.057)S(0.885)PDAPAKDAR 121.0 0.00013953 12374500.0 60649.0 45634.3 71589.0 82490.0 107172.0 100346.0 88667.0 87824.0 87812.0 72280.0 True False 70915.67782764809 50164.571717417944 73295.95326279449 77868.35273618854 86172.41594063934 95083.67911096285 80267.81986651053 85518.71305721982 89096.0843760172 85383.79183183466 0.8305519854086376 0.5875186688384397 0.858429353982692 0.9119804949580131 1.0092362272966033 1.11360337917801 0.9400826333011755 1.0015801737366137 1.0434777194188563 1.0 16.381674612590757 -5.723909900160319 1.8928881572210456 1.0165130520613537 0.7098014250631866 0.7258558242160582 0.0732312599775228 0.16235671853492842 1.1825427898786065 0.021591027290860817 0.045453302490186386 1.8883830772247247e-06 5.723909900160319 -0.3067116269981671 GAANASGSS(ph)PDAPAKDAR ddPTM_PC-9_Lapatinib_30min_R1 3 GAANASGSSPDAPAKDAR 18 1 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 GAANASGS(0.05)S(0.949)PDAPAKDAR;GAANASGS(0.069)S(0.931)PDAPAKDAR;GAANAS(0.307)GS(0.178)S(0.515)PDAPAKDAR 195.48 8.1909e-14 13320400.0 95013.0 58029.0 67277.0 58474.0 58027.0 57956.0 42998.0 39285.0 62328.0 36673.5 True False 93658.09719674989 57894.63741579115 61745.744756730055 62774.373023545755 54613.96594547137 55477.356982034595 45224.22604917019 41110.32451694343 55307.96429706304 43012.46561063292 2.177464041345193 1.345996714996019 1.4355313949141795 1.4594460497058226 1.2697241409004578 1.2897971830826709 1.0514213823164442 0.9557769807732373 1.2858589599985777 1.0 15.392467213047267 -1.5228787452803376 0.47496957518929095 1.1129179951759043 25.64495368367775 0.7726088912501684 0.15671120606287137 47.845256182584684 0.5431040364278354 0.09349166667685467 1155.5538457945977 0.029999999999999995 1.5228787452803376 24.532035688501843 up GAAPT(ph)PPGK ddPTM_PC-9_AZD4547_30min_R2 4 GAAPTPPGK 9 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;H0YAB7;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 GAAPT(1)PPGK;GAAPT(1)PPGK;GAAPT(1)PPGK;GAAPT(1)PPGK 115.7 0.004799800000000001 37722300.0 289205.0 288436.0 369356.0 442623.0 411432.0 400498.0 335475.0 443080.0 327363.0 357561.0 True False 381166.1741623041 381667.2963265979 364458.09810707654 340583.1058071803 354311.7686332709 375454.7967480844 365331.62509881175 374612.16696549725 344666.7398551899 345042.8982230975 1.1046921299503172 1.1061444773739986 1.0562689450615081 0.9870746726308982 1.0268629508327987 1.0881394710095533 1.0588005925645685 1.0856973695000698 0.9989098214458414 1.0 18.39641621373724 -5.330060788426053 4.274753580902636 1.0403546130307761 1.1059189569971186 0.401507320039156 0.03334519870389783 0.22690724436925486 8.064249392509016 0.009242315152290976 0.021129463233859443 4.676696767362005e-06 5.330060788426053 0.06556434396634248 GAAPT(ph)PPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GAAPTPPGK 9 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;H0YAB7;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 GAAPT(1)PPGK;GAAPT(1)PPGK 108.47 0.00595 17847300.0 158139.0 180791.0 179018.0 174360.0 209692.0 162744.0 172479.0 168808.0 143357.0 127338.0 True False 184908.8093123781 198738.73567390596 183286.46804954577 164591.17448274695 168604.35788661725 154209.41814556177 156140.54048017735 164376.9688668609 145453.32492020164 150423.37139294637 1.2292558503382194 1.321195860946015 1.218470682795376 1.094186182363846 1.1208654368354585 1.0251692720190748 1.0380071862124152 1.0927621641816814 0.9669596125474303 1.0 17.198669211486852 -5.860400457668449 1.116501184697623 1.0323956137078747 1.290880648057371 0.8308455101729435 0.04433325533958098 0.20331139278193405 0.5036952443109548 0.01633990543654916 0.03953884188370828 1.3791120156862533e-06 5.860400457668449 0.2584850343494962 GAAPT(ph)PPGK ddPTM_PC-9_Lapatinib_30min_R1 3 GAAPTPPGK 9 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;H0YAB7;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 GAAPT(1)PPGK;GAAPT(1)PPGK;GAAPT(1)PPGK 121.61 0.003927900000000001 32310100.0 248774.0 262299.0 311809.0 244510.0 293674.0 280563.0 262433.0 256617.0 294691.0 251516.0 True False 245226.43714043518 261691.6627811024 286173.2676375476 262492.0810614491 276400.6727052984 268563.9745142965 276020.4966454689 268540.3626464164 261499.7963461972 294990.20547599654 0.8313036588612748 0.8871198362631615 0.9701110827587582 0.8898332086582046 0.9369825423840699 0.9104165817334219 0.9356937671882425 0.9103365388457538 0.8864694199735914 1.0 18.170307528078098 GAAQENGAPECS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 GAAQENGAPECSPR 14 0 Q6IE81-2;Q6IE81;Q6IE81-3 Q6IE81-2 JADE1 Protein Jade-1 1 GAAQENGAPECS(1)PR 111.81 0.0024525 0.0 5766.9 6319.1 11441.0 8178.4 7570.5 8607.3 6299.8 6406.1 9395.1 8303.2 True False 5684.66294848006 6304.468512194347 10500.36514353715 8779.866818342625 7125.218074175659 8239.185843596286 6625.972818841863 6703.750792617826 8336.924903211027 9738.397056681448 0.5837370272944304 0.647382569790466 1.0782436865554708 0.9015720726152584 0.7316623087664202 0.8460515417107004 0.6803966587392151 0.6883833913938052 0.8560880044925997 1.0 13.249468608438905 -12.540721297096221 0.9870603251494263 3.196319231821012 0.7827361510300173 0.18661300597936148 0.13810243055444954 38685.128260003716 1087.2322315524807 187521.5342645102 0.04510033392468467 2.87924554081973e-13 12.540721297096221 -2.413583080790995 GAARLRAVDFAERHGY(ph)IK ddPTM_PC-9_Lapatinib_30min_R1 1 GAARLRAVDFAERHGYIK 18 3 E9PKU4;P62917;E9PKZ0;E9PP36;G3V1A1 E9PKU4 RPL8 60S ribosomal protein L8 1 GAARLRAVDFAERHGY(1)IK 46.592 0.041311 1805900.0 1996.5 882.88 941.27 1249.4 0.0 803.12 569.4 0.0 803.0 804.73 True False 1968.0295438867395 880.8357456039855 863.8824140072733 1341.285043876219 0.0 768.77242976416 598.8807459044025 0.0 712.5576840351301 943.826508264677 2.085160277501811 0.9332602315053573 0.9152978926133477 1.421113978184731 0.0 0.814527270671416 0.6345241849643606 0.0 0.7549668056529175 1.0 9.88237788128014 -1.5228787456997286 0.5996671867737255 0.5460648085798836 89.95366785813003 0.5187120066822808 0.40373947886747646 133.84808616965046 1.0383134033023957 0.1793167192451661 15678.489853016035 0.029999999971029496 1.5228787456997286 89.40760304955015 GAAS(ph)PGPSR ddPTM_PC-9_AZD4547_30min_R2 1 GAASPGPSR 9 0 M0QZR4;Q92888-2;Q92888;Q92888-3;Q92888-4 M0QZR4 ARHGEF1 Rho guanine nucleotide exchange factor 1 1 GAAS(0.997)PGPS(0.003)R 80.24 0.018977 1148300.0 9108.9 11378.0 11120.0 11363.0 9455.5 11651.0 15229.0 15076.0 18994.0 15193.0 True False 12005.34072310997 15055.715991083029 10972.541534321077 8743.435906599956 8142.76703881055 10922.461128175226 16584.351497517833 12746.350612015538 19997.98406298046 14661.097694389291 0.818856880525688 1.0269160130380113 0.7484120059114127 0.5963698004649416 0.555399548420357 0.7449961357501343 1.131180750801801 0.8693994731986191 1.3640168341988173 1.0 13.839705503414482 -7.255879856166094 23.72509770172119 1.0802658981639583 0.7454521781166483 0.5038387743777533 0.16642681940880394 209.64604006056993 894661.9066669235 0.06865169638105464 0.05155826555961072 5.5477916661699507e-08 7.255879856166094 -0.33481372004731 GAAS(ph)PGPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GAASPGPSR 9 0 M0QZR4;Q92888-2;Q92888;Q92888-3;Q92888-4 M0QZR4 ARHGEF1 Rho guanine nucleotide exchange factor 1 1 GAAS(0.999)PGPS(0.001)R;GAAS(1)PGPSR 89.82700000000001 0.0090455 8044800.0 21319.0 45011.0 34207.0 26365.0 58125.0 44165.0 31046.0 36775.0 41477.0 42264.0 True False 24927.885630556608 49479.39461266417 35022.62461076993 24887.85452648327 46735.823503803775 41848.90965196096 28105.098126424597 35809.69521633331 42083.52265822521 49926.128638360075 0.4992953852104527 0.9910520996143758 0.7014888910064773 0.49849357851794296 0.9360994889536643 0.8382165970667093 0.5629336560421875 0.7172535943197368 0.8429157999222654 1.0 15.607507421391162 -8.55266874800296 2.982473720468721 0.9991374418784478 0.7260353149474917 0.23180283827801562 0.16051880397611593 0.39991766672433393 9.13562898016066 0.1519089470332536 0.040523210197255424 2.801117017582633e-09 8.55266874800296 -0.27310212693095604 GAAS(ph)PGPSR ddPTM_PC-9_Lapatinib_30min_R1 1 GAASPGPSR 9 0 M0QZR4;Q92888-2;Q92888;Q92888-3;Q92888-4 M0QZR4 ARHGEF1 Rho guanine nucleotide exchange factor 1 1 GAAS(0.996)PGPS(0.004)R 68.557 0.042736 5595900.0 12975.0 24481.0 18530.0 23837.0 27113.0 12415.0 33392.0 30764.0 22107.0 19250.0 True False 12789.974120676408 24424.315748608147 17006.53492786849 25590.05249790094 25518.266646208922 11884.039390778526 35120.87437168915 32193.407749503564 19617.07686296964 22577.336850987333 0.5664961374803197 1.0818067653333543 0.7532569071415869 1.1334398147486495 1.130260261191655 0.5263702919974294 1.5555809174257536 1.4259169698349834 0.8688835619738633 1.0 14.462587700094982 -7.26743042028672 24.990719920788813 1.248088418664013 0.894257013879881 0.27350860340808736 0.27244241184053664 663.8687474563709 2769215.3868490863 0.1100931584869288 0.07639766276883435 5.402186579973743e-08 7.26743042028672 -0.3538314047841321 GAAS(ph)PVLQEDHCDSLPSVLQVEEK ddPTM_PC-9_AZD4547_30min_R2 3 GAASPVLQEDHCDSLPSVLQVEEK 24 0 Q8N9B5-2;Q8N9B5 Q8N9B5-2 JMY Junction-mediating and -regulatory protein 1 GAAS(1)PVLQEDHCDSLPSVLQVEEK;GAAS(1)PVLQEDHCDSLPSVLQVEEK;GAAS(1)PVLQEDHCDSLPSVLQVEEK 107.75 6.2245e-07 17927600.0 71836.0 85310.0 111359.0 117962.0 106559.0 134402.0 120382.0 140445.0 116739.0 116888.0 True False 94678.35371837718 112884.78917202441 109882.30689932186 90767.6833947325 91765.12219222831 125997.8216933314 131095.76478916514 118742.45235503583 122909.58521260798 112795.78669793824 0.8393784598703259 1.0007890584984749 0.9741703135914239 0.804708101711317 0.8135509745410168 1.1170436891472515 1.1622399083064456 1.0527206363924078 1.0896646835023547 1.0 16.783353653667177 -6.771300330880051 24.999881642878034 1.0924979920968287 0.8931921197869027 0.6568524447886845 0.07128479584536339 135.72826108642397 344101.75574026327 0.02664385285869991 0.02377982060293421 1.693166507520713e-07 6.771300330880051 -0.19930587230992602 GAAS(ph)PVLQEDHCDSLPSVLQVEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GAASPVLQEDHCDSLPSVLQVEEK 24 0 Q8N9B5-2;Q8N9B5 Q8N9B5-2 JMY Junction-mediating and -regulatory protein 1 GAAS(1)PVLQEDHCDSLPSVLQVEEK;GAAS(1)PVLQEDHCDSLPSVLQVEEK;GAAS(1)PVLQEDHCDSLPSVLQVEEK;GAAS(1)PVLQEDHCDSLPSVLQVEEK 141.43 1.2770999999999999e-08 19788400.0 98251.0 146347.0 143891.0 143523.0 158237.0 114414.0 148453.0 104442.0 105618.0 95681.0 True False 114882.95375429488 160875.36298637115 147321.90714965638 135481.87161784395 127231.59576380884 108413.92842566427 134390.45713335436 101700.50816544642 107162.463440375 113027.20788962084 1.0164185765473948 1.423333071657202 1.303419857044746 1.1986660039426231 1.1256722884640271 0.9591843455209319 1.189009793682564 0.8997878481149799 0.9481121000974103 1.0 16.78631057417993 -6.413858069194947 1.800387931467914 1.0011253918940837 1.2632139684034813 0.4636520595406657 0.11895030542369339 0.30716871107207894 1.981200046884495 0.0434656591007207 0.0513007442005063 3.8560435557023336e-07 6.413858069194947 0.26208857650939765 GAAS(ph)PVLQEDHCDSLPSVLQVEEK ddPTM_PC-9_Lapatinib_30min_R1 4 GAASPVLQEDHCDSLPSVLQVEEK 24 0 Q8N9B5-2;Q8N9B5 Q8N9B5-2 JMY Junction-mediating and -regulatory protein 1 GAAS(1)PVLQEDHCDSLPSVLQVEEK;GAAS(1)PVLQEDHCDSLPSVLQVEEK;GAAS(1)PVLQEDHCDSLPSVLQVEEK;GAAS(1)PVLQEDHCDSLPSVLQVEEK 131.98 1.3398e-08 26306400.0 75589.0 132918.0 173593.0 139251.0 160209.0 166470.0 164177.0 180188.0 173780.0 142438.0 True False 74511.08699867527 132610.23653745785 159320.8536283582 149491.98306771828 150785.82160301268 159350.46616052365 172677.28173576965 188560.19228863472 154207.06641547327 167058.21851329505 0.44601868535276773 0.793796544208355 0.9536846199259505 0.8948496182833483 0.9025944544656607 0.9538618786829814 1.0336353594123082 1.1287094640819988 0.9230738109613024 1.0 17.34999143296554 -4.567035881093704 1.2327325995666043 0.9850885202834103 1.3449558195868239e-20 0.8625311179235066 0.06462455624327129 0.8597465926381677 0.8027682001392097 0.02125511113450109 1.2248330894440393 2.7099677270821873e-05 4.567035881093704 -0.9850885202834103 down GAASPVLQEDHCDS(ph)LPSVLQVEEK ddPTM_PC-9_AZD4547_30min_R2 1 GAASPVLQEDHCDSLPSVLQVEEK 24 0 Q8N9B5-2;Q8N9B5 Q8N9B5-2 JMY Junction-mediating and -regulatory protein 1 GAAS(0.013)PVLQEDHCDS(0.987)LPSVLQVEEK 96.633 3.0773e-06 9091400.0 16498.0 19132.0 25587.0 25034.0 30135.0 25834.0 23938.0 27833.0 26745.0 28657.0 True False 21744.02082028218 25316.04485334863 25247.699661751187 19262.79807144446 25951.275417963712 24218.59589608437 26068.435625949303 23532.049388712436 28158.68609900035 27653.727152511954 0.78629620883878 0.9154659230464355 0.9129944590292881 0.6965714952349453 0.9384368072643836 0.8757805326753016 0.9426734950475328 0.8509539874654791 1.0182600682976122 1.0 14.755186318673635 -7.938225482167021 0.6389648774481187 1.0075376441983759 0.846067485236686 0.36005345180377546 0.07358138161731431 0.8526992791056218 0.7400254690470284 0.07007887403703712 0.034920376773810824 1.1528545496953341e-08 7.938225482167021 -0.16147015896168992 GAASTLVPGVS(ph)ETSASPGSPSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GAASTLVPGVSETSASPGSPSVR 23 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 GAASTLVPGVS(0.862)ET(0.057)S(0.013)AS(0.058)PGS(0.009)PSVR;GAASTLVPGVS(0.372)ET(0.143)S(0.077)AS(0.353)PGS(0.054)PSVR 268.49 5.5105e-96 28379000.0 118565.0 115159.0 137145.0 140735.0 144778.0 139530.0 134237.0 127121.0 114778.0 98120.0 True False 138635.71273450687 126591.22446068279 140415.05692530915 132850.07421902622 116409.7901975693 132212.80117147302 121521.09956828135 123784.20844583325 116456.41111135735 115908.37928250754 1.196080159110889 1.0921662889629193 1.2114314581439418 1.1461645399701959 1.0043259246498448 1.1406664642357405 1.0484237664310165 1.0679487472094635 1.0047281467676643 1.0 16.822625340283764 -6.636981493553332 0.36439349910188534 0.9951302928923172 1.1992503498985516 0.5627514761360521 0.04976378588673019 1.4503417446964437 0.37916420510972243 0.05543691337839971 0.11404402708350624 2.3068454874670653e-07 6.636981493553332 0.20412005700623437 GAASTLVPGVSET(ph)SASPGSPSVR ddPTM_PC-9_Lapatinib_30min_R1 2 GAASTLVPGVSETSASPGSPSVR 23 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 GAASTLVPGVS(0.138)ET(0.475)S(0.246)AS(0.132)PGS(0.009)PS(0.001)VR;GAASTLVPGVS(0.037)ET(0.73)S(0.114)AS(0.114)PGS(0.004)PS(0.001)VR 151.28 4.9366e-06 73489000.0 200490.0 163518.0 184457.0 151723.0 170454.0 168015.0 154390.0 140712.0 183177.0 117380.0 True False 197630.97583463727 163139.3841175163 169291.6574846106 162881.21555309047 160428.23084545796 160829.39011209446 162383.55876392825 147249.99321441117 162545.67732067613 137668.9766009814 1.4355520082599962 1.1850119623563276 1.2297008495623825 1.1831366773734653 1.1653186854903541 1.1682326264270926 1.179521797671086 1.0695945945846557 1.180699394546944 1.0 17.07084396240267 -1.5228787452803376 0.5362960631496917 1.1269353302426226 12.00941075592215 0.6753444423860757 0.060503336851013514 76.22315619416538 0.7286574117231709 0.029102302237106997 950.2205182110187 0.029999999999999995 1.5228787452803376 10.882475425679528 GAASTLVPGVSETS(ph)ASPGSPSVR ddPTM_PC-9_AZD4547_30min_R2 2 GAASTLVPGVSETSASPGSPSVR 23 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 GAASTLVPGVS(0.003)ET(0.053)S(0.725)AS(0.205)PGS(0.014)PS(0.001)VR;GAASTLVPGVS(0.054)ET(0.189)S(0.447)AS(0.311)PGSPSVR 229.51 4.810499999999999e-47 86235000.0 225500.0 225270.0 327840.0 421120.0 342340.0 328070.0 258270.0 368700.0 259560.0 354420.0 True False 297204.3093086205 298084.1221050516 323492.6273931495 324037.2902391422 294812.00021853956 307555.73103771795 281255.52966471383 311725.8868831338 273279.8116977575 342011.86367705173 0.8689883038363219 0.8715607666362142 0.9458520646482917 0.9474445908260006 0.8619934906612446 0.8992545689237571 0.8223560628595395 0.911447584103352 0.7990360590409368 1.0 18.383686844492992 -6.296868316862171 24.963301299070366 0.8757660755252138 0.9084964647540459 0.04121365016468981 0.056591780711494906 1682.447941198966 1185451.0583132333 0.016829916987624052 0.01908408669682354 5.048143399391846e-07 6.296868316862171 0.03273038922883209 GAASTLVPGVSETS(ph)ASPGSPSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GAASTLVPGVSETSASPGSPSVR 23 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 GAASTLVPGVS(0.209)ET(0.145)S(0.483)AS(0.113)PGS(0.049)PSVR 225.5 1.0761e-46 23769000.0 74422.0 77244.0 89345.0 94326.0 104480.0 75858.0 87475.0 85290.0 81826.0 68979.0 True False 87020.17469849829 84912.27383218847 91475.32364279928 89041.22002901798 84007.89401595535 71879.87293962308 79188.7347358432 83051.227872225 83022.5504504168 81484.34666253645 1.067937318794347 1.042068535983342 1.1226122241814123 1.092740184783931 1.0309697194219405 0.8821310580952456 0.9718275715432755 1.0192292295866066 1.0188772917852646 1.0 16.314235320349404 -6.524994394975394 24.9979534309533 0.9766862742050213 1.079029099654271 0.5854390244520336 0.04083430442797357 51.94142476040977 613711.9734033797 0.014415326228843246 0.014507536011351721 2.9854211486523083e-07 6.524994394975394 0.10234282544924977 GAASTLVPGVSETSAS(ph)PGSPSVR ddPTM_PC-9_AZD4547_30min_R2 1 GAASTLVPGVSETSASPGSPSVR 23 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 GAASTLVPGVS(0.049)ET(0.066)S(0.143)AS(0.701)PGS(0.029)PS(0.011)VR 118.61 1.2181e-08 5839200.0 33260.0 29996.0 42224.0 63751.0 52616.0 40193.0 37792.0 48526.0 38964.0 47394.0 True False 43835.9881490232 39691.62039624949 41664.082171328526 49054.191893131545 45311.17661827041 37679.725356170864 41155.41478719507 41027.421716547215 41023.55749341745 45734.75048561086 0.9584831596012523 0.8678656814523856 0.9109939756736389 1.0725802889985168 0.9907384677331144 0.8238751705451136 0.8998718556504086 0.8970732600685191 0.8969887680118502 1.0 15.48100315975014 -6.733760601311907 24.99972023097479 0.8968981730922444 0.9585235870754589 0.16090621984008469 0.0636363903065339 406.275020125771 366950.2525986031 0.022164993669078405 0.022160268407752166 1.8460327381888174e-07 6.733760601311907 0.06162541398321453 GACAGSEDAVK ddPTM_PC-9_Lapatinib_30min_R1 1 GACAGSEDAVK 11 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 154.56 3.6072e-08 0.0 13083.0 15655.0 15166.0 14156.0 13530.0 12051.0 13074.0 15189.0 15954.0 11813.0 False True 12896.434020871638 15618.751809340332 13919.110022452973 15197.079463031676 12734.192001003466 11535.60682225308 13750.9077484267 15894.736390170636 14157.092516932093 13854.861310166925 0.9308237543603575 1.1273120285858824 1.0046372685260228 1.096877054401101 0.9191136393158196 0.8326035579863987 0.9924969612172196 1.1472317213674896 1.0218140910976412 1.0 13.758104648785535 -10.474920279125824 6.408432837324043 0.9999999980815447 1.009970660646289 0.0003186512562071142 0.09306700757489528 2.7247525611538764e-09 4.453751041223415e-10 0.09576958518095793 0.023227531874868222 3.35026932429824e-11 10.474920279125824 0.009970662564744326 GACS(ph)TPDMPQFEPVK ddPTM_PC-9_AZD4547_30min_R2 1 GACSTPDMPQFEPVK 15 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 GACS(0.821)T(0.179)PDMPQFEPVK 99.834 0.010092 0.0 8322.3 16598.0 12056.0 8840.5 10942.0 13529.0 15157.0 20185.0 15415.0 14379.0 True False 10968.618285406365 21962.978908419413 11896.129562749535 6802.459309363453 9422.89217266829 12683.0294912954 16505.94363700032 17065.872055156127 16229.805429653785 13875.595586626983 0.7904971153798757 1.5828494547352536 0.8573419056847392 0.4902462937100534 0.6790982133948816 0.9140529797163478 1.1895664970884863 1.2299199662178009 1.1696654985603459 1.0 13.760262077601885 -7.235003743090707 6.60099429270973 1.1667429662382895 0.8878824902225981 0.1828393622009955 0.269803999376771 0.3552162423394614 59.858739918878406 0.1163111538824816 0.08755930021660176 5.820982007700892e-08 7.235003743090707 -0.2788604760156914 GACST(ph)PDMPQFEPVK ddPTM_PC-9_AZD4547_30min_R2 3 GACSTPDMPQFEPVK 15 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 GACS(0.094)T(0.906)PDMPQFEPVK;GACS(0.066)T(0.934)PDMPQFEPVK;GACS(0.024)T(0.976)PDMPQFEPVK 148.41 0.00033979 24591000.0 55583.4 97245.0 83923.0 53368.0 62664.0 99834.0 106445.0 142808.0 111623.0 76329.0 True False 73257.76499345807 128677.54452037861 82810.1261856859 41064.832127380694 53964.18525937542 93591.36419794391 115918.3987887114 120740.3050013738 117523.16389712889 73656.7449427396 0.9945832530396 1.746989289581177 1.124270781312181 0.5575162486382516 0.7326441767325846 1.2706421424229564 1.5737648857389206 1.6392294432130652 1.5955519618534708 1.0 16.168530022256412 -6.999786111542967 24.96518165657539 1.4935197087635512 1.0450036773816642 0.2577602711590675 0.3344345440102671 10.698124560873168 1248500.7456228454 0.1291051022395637 0.1127609234576238 1.0004926176689777e-07 6.999786111542967 -0.448516031381887 GACST(ph)PDMPQFEPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GACSTPDMPQFEPVK 15 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 GACS(0.182)T(0.818)PDMPQFEPVK;GACS(0.095)T(0.905)PDMPQFEPVK;GACS(0.105)T(0.895)PDMPQFEPVK 168.67 0.00058853 14943300.0 76813.6 181575.0 136478.0 102716.2 127222.0 55291.3 96717.1 60890.9 58851.7 67898.4 True False 89816.625342245 199600.5660126297 139732.15311569758 96961.34432441335 102293.76237076876 52391.72689322923 87555.3561168338 59292.57839424151 59712.29477602219 80207.84243656138 1.1197985460497017 2.4885417678514337 1.742125818011071 1.2088761071101344 1.275358609124485 0.6531995538300049 1.0916059260175686 0.7392366705430041 0.7444695301865314 1.0 16.291455684698278 -6.040506580655405 1.55687997068531 0.8643128481089722 1.8666730022193567 0.550671006877756 0.3506601531007536 0.2664391962560952 1.3002728827629118 0.1171371547004945 0.1938676622373177 9.109476490097424e-07 6.040506580655405 1.0023601541103844 GACST(ph)PDMPQFEPVK ddPTM_PC-9_Lapatinib_30min_R1 4 GACSTPDMPQFEPVK 15 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 GACS(0.159)T(0.841)PDMPQFEPVK;GACS(0.145)T(0.855)PDMPQFEPVK;GACS(0.229)T(0.771)PDMPQFEPVK;GACS(0.029)T(0.971)PDMPQFEPVK 159.41 2.4793e-05 27052400.0 40913.200000000004 175749.0 131475.0 122985.0 158731.0 144399.0 156551.0 168796.0 133249.0 125817.0 True False 40329.77026543801 175342.06398848596 120665.6330081763 132029.72716593344 149394.75465715298 138223.39138050968 164656.44477007387 176638.87838009378 118241.09444582458 147564.3008093855 0.27330302820011687 1.1882417564867676 0.8177156151340748 0.8947267492323996 1.0124044490281694 0.9366993956015024 1.1158284481201652 1.1970298873862795 0.8012852281837541 1.0 17.17098421700961 -4.751955333071685 24.99387905403485 0.9958187229504921 0.27330159699672135 0.728154854492238 0.13247124792686482 197.84705950298175 521361.37999046926 0.03265960297057332 0.4093640951005201 1.7702910223299674e-05 4.751955333071685 -0.7225171259537708 GADAGSSGGTGPTEGYS(ph)PPAASTR ddPTM_PC-9_AZD4547_30min_R2 1 GADAGSSGGTGPTEGYSPPAASTR 24 0 J3KT76;J3KSI9;Q969W3;Q969W3-2 J3KT76 FAM104A Protein FAM104A 1 GADAGSSGGTGPT(0.002)EGY(0.001)S(0.997)PPAASTR 165.41 3.7098999999999997e-34 0.0 1583.0 4700.8 4208.7 6841.5 6461.7 2982.0 3193.2 4703.7 3419.9 4283.4 True False 2086.3610715545315 6220.241670845763 4152.889888084271 5264.297875121328 5564.604492060928 2795.5350685965623 3477.38861395193 3976.8512452731165 3600.668932135776 4133.439469765491 0.5047518142736709 1.5048585364185014 1.0047056255355986 1.2735877502568087 1.3462407113407262 0.6763217627945973 0.8412820943399997 0.9621167249120843 0.8711072119171637 1.0 12.013127044731995 -6.762343793714347 24.999877059645375 0.8659926533587758 1.1491991676797082 0.19231473518457087 0.2609199326080132 37.33526939928143 1032005.5980812621 0.08520459912985567 0.07951400105725562 1.7284475537348567e-07 6.762343793714347 0.28320651432093236 GADAGSSGGTGPTEGYS(ph)PPAASTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GADAGSSGGTGPTEGYSPPAASTR 24 0 J3KT76;J3KSI9;Q969W3;Q969W3-2 J3KT76 FAM104A Protein FAM104A 1 GADAGSSGGTGPTEGYS(1)PPAASTR;GADAGSSGGTGPTEGYS(1)PPAASTR;GADAGSSGGTGPTEGYS(1)PPAASTR 217.54 4.573999999999999e-100 7006600.0 17177.899999999998 13830.0 18322.4 20646.0 21245.7 19887.1 14833.7 19699.2 18045.5 11572.6 True False 20085.77919100983 15202.951000714156 18759.27550408896 19489.271555235126 17082.757598533557 18844.18546676129 13428.544549312133 19182.11687302769 18309.381298768058 13670.620771348813 1.469266065305977 1.1120892938948927 1.3722328940178827 1.4256317896025006 1.2495963339379565 1.3784440210831792 0.9822922290007468 1.4031635573733412 1.339323327375247 1.0 13.738791135544798 GADAGSSGGTGPTEGYS(ph)PPAASTR ddPTM_PC-9_Lapatinib_30min_R1 3 GADAGSSGGTGPTEGYSPPAASTR 24 0 J3KT76;J3KSI9;Q969W3;Q969W3-2 J3KT76 FAM104A Protein FAM104A 1 GADAGSSGGTGPT(0.001)EGYS(0.997)PPAAS(0.002)TR;GADAGSSGGTGPTEGY(0.002)S(0.997)PPAAS(0.001)TR;GADAGSSGGTGPT(0.002)EGYS(0.998)PPAASTR 258.2 1.7427999999999994e-172 6905900.0 19479.9 15494.000000000002 16960.5 14740.5 15129.300000000001 15774.199999999999 13220.3 15097.3 16868.5 11959.1 True False 19202.113053823854 15458.124594948524 15566.073159423291 15824.565542866507 14239.424319348249 15099.574237456189 13904.782446575291 15798.775673403343 14968.591896820179 14026.214500500917 1.369016070097751 1.102088136068108 1.1097843369547344 1.128213570546876 1.0152008098007996 1.0765252618172165 0.9913424927359203 1.1263748798964341 1.0671868661559116 1.0 13.775838075730396 -1.9867575396646118 1.1102736926719539 1.0610046991007127 199.99999999967773 0.7891761217168785 0.04695214592705973 460.0125754232003 1.1698423777977938 0.014174826406573039 232308.80807784788 0.010309615307342868 1.9867575396646118 198.938995300577 GADDDRPSWR ddPTM_PC-9_AZD4547_30min_R2 1 GADDDRPSWR 10 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 96.665 0.0070558999999999995 13419000.0 74707.0 76983.0 83741.0 122950.0 106210.0 103450.0 88130.0 114940.0 80743.0 95052.0 False True 98462.27199786744 101866.2492653845 82630.53962460262 94605.77705856418 91464.57481804947 96981.2551463162 95973.39926956774 97178.66405844183 85010.91013989857 91724.2584115772 1.0734594501277515 1.1105704317422662 0.9008580832982042 1.0314150116543572 0.997168866796802 1.0573130470147847 1.0463251590318035 1.0594652466132797 0.9268094570843508 1.0 16.48501571491572 -5.14898755528455 20.663220675041064 1.0086818590670785 1.0920276389412888 0.3242649731401941 0.0510939672632788 7.816322895865341 1423.6029265878528 0.0128493155369085 0.03399644938436458 7.095981012172066e-06 5.14898755528455 0.08334577987421032 GADDDRPSWR ddPTM_PC-9_Lapatinib_30min_R1 1 GADDDRPSWR 10 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 104.42 0.0033789000000000002 11176000.0 62235.0 99605.0 105430.0 73083.0 92804.0 92162.0 101870.0 86028.0 84122.0 74969.0 False True 61347.517487498764 99374.37074221286 96761.95237156912 78457.76761774124 87345.45117968415 88220.44610011525 107144.33014626183 90025.17494065427 74647.2945160687 87927.29176008672 0.6977073472806148 1.1301880082166067 1.1004768876037732 0.8923027884427115 0.9933827078173846 1.0033340540139506 1.2185560137415536 1.0238592948625291 0.8489661517125644 1.0 16.42402341267354 -6.856029699143763 4.3567719647932375 1.035018236647897 0.975772852006947 0.031797048515775805 0.13929178598298808 0.9361423344179546 31.92078363224789 0.05110121724182614 0.045267652025695757 1.3930615354454818e-07 6.856029699143763 -0.05924538464095008 GADFLVTEVENGGS(ph)LGSK ddPTM_PC-9_AZD4547_30min_R2 1 GADFLVTEVENGGSLGSK 18 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 1 GADFLVT(0.001)EVENGGS(0.995)LGS(0.005)K 69.935 0.010508 1738400.0 6100.9 8103.0 10770.0 12317.0 12105.0 8646.1 7018.8 13469.0 7316.4 8682.9 True False 8040.859293396741 10722.136287198611 10627.182763007006 9477.505945753035 10424.429697509562 8105.458000198765 7643.459602782723 11387.675536829218 7703.129967273366 8378.914313869067 0.9596540783436864 1.2796569920104044 1.2683245543419066 1.1311138401386371 1.2441265427735295 0.9673637534140113 0.9122255362047331 1.3590872409304802 0.9193470273974375 1.0 13.032547605499703 -6.756385613981092 24.993619105769728 1.0465864644815968 1.1848735232684924 0.1931031241188259 0.14608862030033046 228.79457390430767 1131512.743718319 0.04839768012697092 0.046969446576667635 1.7523239067110212e-07 6.756385613981092 0.13828705878689562 GADFLVTEVENGGSLGSK ddPTM_PC-9_AZD4547_30min_R2 1 GADFLVTEVENGGSLGSK 18 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 187.37 4.6511000000000006e-10 1822100.0 5086.6 7757.8 7616.3 8083.9 10342.0 8937.0 6937.9 9440.9 7517.3 7261.8 False True 6704.032992147371 10265.357137952531 7515.302885597985 6220.281750009979 8906.191815914408 8378.167977212426 7555.359659506788 7982.025835299647 7914.649131127886 7007.566592319894 0.956684878242158 1.4648961237418834 1.072455436075992 0.887652178265026 1.2709393051898152 1.1955887777641208 1.0781716534506087 1.1390581495219374 1.1294432991620986 1.0 12.774697833795445 -14.522878743565874 0.26954033475241485 0.05330872603769685 1.1478448202797842 0.06161272123049044 0.15223356540716376 646.5474224890428 6.275314645380241 340.46068673119976 0.18690779238588434 3.0000000118430937e-15 14.522878743565874 1.0945360942420874 GADFLVTEVENGGSLGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GADFLVTEVENGGSLGSK 18 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ;; 262.23 6.931099999999998e-66 13393200.0 78466.0 82009.0 83287.0 98449.0 102317.0 77513.0 82777.0 71550.0 79181.0 83119.0 False True 91748.74402585739 90150.3115414005 85272.87794770641 92933.22170596456 82268.71833873005 73448.08182616203 74935.76330641775 69671.88831349164 80338.8723292651 98187.816730358 0.9344208587284969 0.9181415224759506 0.8684669930270635 0.9464842462194314 0.8378709403902446 0.7480366126060641 0.7631879982850143 0.7095777320807897 0.8182163022311676 1.0 16.58325640375213 -6.477344981710794 4.586293553587406 0.7869704831194302 0.9126034443924157 0.2956134968810651 0.07624584798203216 0.2194096777627384 10.234449583389747 0.023274671021553624 0.025655372961493467 3.331616607441744e-07 6.477344981710794 0.1256329612729855 GADFLVTEVENGGSLGSK ddPTM_PC-9_Lapatinib_30min_R1 4 GADFLVTEVENGGSLGSK 18 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ;;; 299.17 1.2366999999999996e-120 88262000.0 286184.0 281965.0 347077.0 288415.0 288819.0 282205.0 300241.0 281908.0 266957.0 317622.0 False True 282102.96368028224 281312.12736637803 318541.6688159637 309626.0012242354 271831.23426000134 270135.7500019855 315786.00988950435 295006.47483575117 236889.49147816483 372522.53949528746 0.7572775705397309 0.7551546484878849 0.8550936790228592 0.831160449093181 0.7297041264356572 0.7251527662406125 0.8476963845391673 0.7919157730306493 0.6359064656842369 1.0 18.50696819298964 -11.221681175841027 6.136632246818508 1.003201623927092 0.7742077475318585 0.5448747504742 0.0629794868044953 0.0028379805688023515 0.00013929333789406987 0.06273253082575746 0.015032841301678668 6.002315563967077e-12 11.221681175841027 -0.2289938763952335 GADFLVTEVENGGSLGSKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GADFLVTEVENGGSLGSKK 19 1 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 114.56 0.00086081 0.0 10983.0 11334.0 14703.0 13991.0 16857.0 18730.0 13915.0 17422.0 15339.0 13206.0 False True 12842.204975862065 12459.164616203483 15053.575281438008 13207.129629434006 13553.991858987016 17747.76582771944 12596.870464124157 16964.690960134853 15563.303856463015 15600.143261361527 0.8232107077932848 0.7986570640708391 0.9649639127816692 0.846603098969319 0.8688376530847365 1.1376668489754929 0.8074842809504267 1.0874702030559578 0.9976385213724444 1.0 13.929271657451512 -5.718565238877066 0.4529166834082092 1.01796187727697 0.7566650561877577 0.3331576660327086 0.09413108035890551 2.656157964569769 0.774109493529207 0.07559262127623857 0.344162483471475 1.9117661212244844e-06 5.718565238877066 -0.26129682108921237 GADNDGS(ph)GSESGYTTPK ddPTM_PC-9_AZD4547_30min_R2 3 GADNDGSGSESGYTTPK 17 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 GADNDGS(0.972)GS(0.005)ES(0.022)GY(0.001)T(0.001)TPK;GADNDGS(0.999)GS(0.001)ESGYTTPK;GADNDGS(0.774)GS(0.187)ES(0.032)GY(0.005)T(0.002)TPK 211.43 5.889e-18 105744000.0 238102.0 204438.0 286851.0 357849.0 331212.0 284534.0 268444.0 336784.0 289687.0 303692.0 True False 313813.4831707375 270518.58549701504 283047.1683148861 275352.4417619369 285228.93093527795 266742.04400001746 292334.9959550649 284741.77132641565 304999.26341226825 293059.8355166501 1.0708170999192017 0.923083113795188 0.965834051656679 0.9395775483068297 0.9732788201168315 0.9101965253265236 0.9975266499405919 0.9716164988096369 1.0407405807574057 1.0 18.16083573154131 -7.988643544219209 2.116132521898049 1.0181865160701389 0.9627168916044521 0.1627947004072995 0.043595313536213674 0.5358987211128653 4.431401509049594 0.034046105869616095 0.011599012178664806 1.0264940959105245e-08 7.988643544219209 -0.05546962446568682 GADNDGS(ph)GSESGYTTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GADNDGSGSESGYTTPK 17 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 GADNDGS(0.989)GS(0.01)ES(0.001)GYT(0.001)TPK;GADNDGS(0.98)GS(0.019)ES(0.001)GYTTPK;GADNDGS(0.998)GS(0.002)ESGYTTPK 199.97 1.0675e-53 69431000.0 252322.5 241354.5 288540.8 342728.0 343650.0 302579.0 332805.0 343801.0 295328.0 241621.3 True False 295035.71565346007 265314.5797036784 295420.70696907706 323526.0612991677 276314.24941216625 286711.2245801129 301279.3011004561 334776.58803727 299646.61329431523 285425.3290168411 1.033670405740522 0.9295411189243962 1.035019239486087 1.1334875654293406 0.9680789380674157 1.0045051907891327 1.0555450777204134 1.1729042730384907 1.0498248852912246 1.0 18.122753841575452 -7.52135320851365 24.99861029862024 1.0896636800284158 1.0182951829341078 0.1293271814153838 0.0639767121271336 99.27782593791426 1626929.187636874 0.029890505471603778 0.017551430034149707 3.0105565647061097e-08 7.52135320851365 -0.07136849709430804 GADNDGS(ph)GSESGYTTPK ddPTM_PC-9_Lapatinib_30min_R1 5 GADNDGSGSESGYTTPK 17 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 GADNDGS(1)GSESGYTTPK;GADNDGS(0.996)GS(0.004)ESGYTTPK;GADNDGS(0.997)GS(0.003)ESGYTTPK;GADNDGS(0.912)GS(0.043)ES(0.043)GYT(0.002)TPK;GADNDGS(0.99)GS(0.01)ESGYTTPK 197.1 3.1205e-12 206533100.0 491531.0 468256.0 459783.0 437207.0 488047.0 465058.0 398225.0 417398.0 544296.0 358363.0 True False 484521.6778042549 467171.7820015631 421981.41655370506 469360.66125979734 459341.0349973197 445168.55344314774 418843.1419701102 436791.8348663147 482991.65278902266 420305.56706131843 1.15278434495151 1.1115051015572377 1.0039872169766957 1.1167129299320517 1.0928740207010068 1.0591545492858105 0.9965205669260268 1.0392244811798819 1.1491440766916108 1.0 18.681079039940656 -6.837347028201879 4.615954332483861 1.0469111542992964 1.0925905226955983 0.16614547168576344 0.052630376899167094 0.44767959131563706 17.724738682868153 0.0193398579014036 0.017216435109876364 1.454296543121383e-07 6.837347028201879 0.045679368396301934 GADNDGSGS(ph)ESGYTTPK ddPTM_PC-9_AZD4547_30min_R2 1 GADNDGSGSESGYTTPK 17 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 GADNDGS(0.378)GS(0.615)ES(0.007)GYTTPK 192.22 3.5676999999999996e-09 76754000.0 249300.0 223720.0 313270.0 374560.0 360220.0 301970.0 280140.0 309330.0 303320.0 323270.0 True False 328572.21423786733 296033.1149169532 309115.83511301794 288210.97889431333 310209.6708498053 283087.7681636829 305071.9172969103 261530.15619625736 319352.8759599473 311952.4156957299 1.0532767105042968 0.9489688171086197 0.9909070087616225 0.9238940440692938 0.9944134273105792 0.9074709921137434 0.9779437566352086 0.8383655424273007 1.023723042014958 1.0 18.250966455846978 -2.138149243561163 1.2906312557790929 0.9489182207428523 123.32051610374268 0.21883686084047682 0.05262680510173869 2314.861099456353 4.292257464085541 0.014118833458430515 838387.6308835063 0.007275297488864986 2.138149243561163 122.37159788299982 GADNDGSGS(ph)ESGYTTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GADNDGSGSESGYTTPK 17 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 GADNDGS(0.001)GS(0.967)ES(0.032)GYTTPK 154.31 2.6084e-05 51228000.0 41878.0 42211.0 48494.0 54087.0 60177.0 50170.0 59145.0 58749.0 51337.0 44818.0 True False 48967.11827179749 46401.42911721945 49650.280874519165 51056.680742419936 48385.74883420899 47538.99688076266 53542.35742728159 57206.90099971083 52087.70650493783 52943.14862090723 0.9249000021215283 0.8764387900211802 0.937803703932189 0.9643680452026926 0.9139189884732597 0.8979253806976928 1.0113179669510197 1.0805345448819763 0.9838422508246594 1.0 15.69215637651141 -7.333727297502376 5.50228237873729 1.0274223526248343 0.9200280339554235 0.6964671721099208 0.03213698743397178 0.12273019081478473 6.849619510335007 0.013788105514812486 0.00922399124179328 4.6373801903732785e-08 7.333727297502376 -0.10739431866941074 GADNDGSGS(ph)ESGYTTPKK ddPTM_PC-9_AZD4547_30min_R2 1 GADNDGSGSESGYTTPKK 18 1 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 GADNDGS(0.339)GS(0.617)ES(0.042)GYT(0.001)TPKK 57.806000000000004 0.015263999999999998 4581100.0 10390.0 6815.4 10380.0 21008.0 17078.0 13133.0 10016.0 14174.0 7634.5 13165.0 True False 13693.803874574596 9018.344767588966 10242.354417828485 16164.930170364505 14707.014487737979 12311.791433896258 10907.404596436967 11983.73398611756 8038.044083859345 12704.097357114139 1.0779045129803129 0.7098768620927486 0.8062244904076472 1.2724186312467405 1.1576591452601102 0.9691197326193196 0.8585737569406263 0.9432967686922532 0.6327127270760515 1.0 13.633006253195191 -7.226354240035658 4.263287697299128 0.852485532187375 0.9981809393297966 0.13494483593603435 0.17479263556101327 0.5070704397756224 21.35848708865989 0.07706846619010259 0.05648895517323117 5.938076112645811e-08 7.226354240035658 0.14569540714242157 GADNDGSGS(ph)ESGYTTPKK ddPTM_PC-9_Lapatinib_30min_R1 1 GADNDGSGSESGYTTPKK 18 1 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 GADNDGS(0.081)GS(0.344)ES(0.344)GY(0.139)T(0.085)T(0.006)PKK 52.483000000000004 0.025118 4349200.0 38517.0 22353.0 24383.0 18336.0 18081.0 19998.0 14747.0 14487.0 21146.0 18098.0 True False 37967.7405168473 22301.243001864223 22378.32386110188 19684.49060710291 17017.51112861373 19142.732157614886 15510.527502374825 15160.118907393657 18764.314802748275 21226.215185930836 1.788719288119395 1.0506462318654877 1.0542776309897528 0.9273669580128533 0.8017214081525603 0.9018438751296122 0.7307250664572323 0.7142167727312069 0.8840160451772694 1.0 14.373559528971208 -1.8406627352361997 0.867786803030649 0.8309082137805752 199.99999888904827 0.8890603418946592 0.09695327733397255 115.20676137544964 0.552072416585802 0.03253444552739428 44998.92880256925 0.014432357056099528 1.8406627352361997 199.16909067526768 GADNDGSGSES(ph)GYTTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GADNDGSGSESGYTTPK 17 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 GADNDGS(0.133)GS(0.166)ES(0.701)GYTTPK 139.12 7.6276e-05 18999000.0 91467.0 91937.0 111930.0 126670.0 131720.0 125690.0 114950.0 125880.0 118520.0 105630.0 True False 106950.55654440288 101063.89776953436 114598.83569688865 119573.09056968105 105910.41155993193 119098.5951354007 104061.10383406898 122575.78338088463 120253.1307821887 124779.88283337979 0.8571137760019807 0.8099374312162667 0.9184079444113117 0.9582721818175496 0.8487779372365295 0.9544695220978417 0.8339573773524306 0.9823360993579525 0.9637221004828501 1.0 16.929025834310444 -1.5228787647522988 0.09063579463610492 1.0698626298183025 0.43590182672511696 0.4253350752082353 0.04963121113862284 153.22994515957086 1.001601076996543 0.9089478679957366 12.07469030199253 0.0299999986549246 1.5228787647522988 -0.6339608030931856 GADNDGSGSESGYT(ph)TPK ddPTM_PC-9_Lapatinib_30min_R1 1 GADNDGSGSESGYTTPK 17 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 GADNDGSGSES(0.001)GY(0.004)T(0.596)T(0.399)PK 105.5 0.001756 16912000.0 42483.0 34266.0 31922.0 32939.0 35359.0 29734.0 29405.0 33076.0 31219.0 31767.0 True False 41877.18462957196 34186.65918229676 29297.49638248346 35361.44394128286 33279.25313846868 28462.3461333394 30927.44702022998 34612.83170987451 27702.787469355848 37257.883623133195 1.1239818410826392 0.9175684676053492 0.7863435475517139 0.9490996401987565 0.8932137282700028 0.7639281506496333 0.8300913528278702 0.9290069199846771 0.7435416286542738 1.0 15.18525810608001 -4.794509630366936 3.441080827304937 0.8584692919390207 1.1533121924927379 0.4940412086729664 0.07926368987818214 0.22595293971313632 4.387119199254918 0.01909646334995703 0.17260619080160658 1.6050566659890635e-05 4.794509630366936 0.2948429005537172 GADNDGSGSESGYT(ph)TPKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GADNDGSGSESGYTTPKK 18 1 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 GADNDGS(0.001)GS(0.004)ES(0.013)GYT(0.49)T(0.49)PKK 69.03 0.009679799999999999 5563200.0 11695.0 8557.7 7908.1 13637.0 11771.0 11751.0 11892.0 14906.0 10383.0 9945.8 True False 13674.732513221054 9407.251900130992 8096.659095636266 12872.963101750529 9464.557048830518 11134.756873546778 10765.503669375808 14514.733294212492 10534.831732293853 11748.894809090525 1.1639164989919257 0.8006924951657817 0.6891421897293354 1.095674385627342 0.8055699878687708 0.9477280250165685 0.9162992642547252 1.2354126520038244 0.8966657633314319 1.0 13.520237431792046 -7.569424741313098 24.998878666935738 1.054795045050071 0.9068028001897485 0.12373559472120166 0.15263306033324017 224.1094771371021 120362.03400822691 0.06932301112670665 0.04002367389317556 2.695102324903591e-08 7.569424741313098 -0.14799224486032247 GADNDGSGSESGYTT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 GADNDGSGSESGYTTPK 17 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 GADNDGSGSESGYT(0.011)T(0.989)PK;GADNDGSGSESGYT(0.119)T(0.881)PK 150.59 0.00012651 28985000.0 57677.0 47122.0 47472.0 57151.0 58571.0 54191.0 51376.0 51345.0 46822.0 54427.0 True False 76017.08624387278 62353.26497906615 46842.4902623462 43975.719924148056 50439.427659052686 50802.428203325355 55948.364471500194 43410.81004072287 49296.91533099246 52521.52729628949 1.4473510226585355 1.1871944360512008 0.8918722031462231 0.8372894351694686 0.960357214566685 0.9672686766463171 1.065246335200401 0.8265336572531419 0.9386039947561685 1.0 15.680621249145545 -4.969244664557192 2.6248635415875854 0.9331732112788238 1.4643181065704878 0.8446179107289815 0.06969499687436721 0.12452742644852026 1.4843156436358904 0.01926269504634155 0.12231559921165229 1.0733845390295459e-05 4.969244664557192 0.531144895291664 GADNDGSGSESGYTT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GADNDGSGSESGYTTPK 17 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 GADNDGSGSESGYT(0.107)T(0.893)PK;GADNDGSGSESGYT(0.122)T(0.877)PK 193.41 1.2414000000000001e-11 23516000.0 87910.0 98694.0 101341.0 113115.0 113419.0 102861.0 112319.0 123333.0 104162.0 79928.0 True False 102791.42669835505 108491.68807407707 103757.35377788293 106777.53327377774 91195.36113510393 97466.78808355832 101679.33120085957 120095.63943211551 105685.17219485623 94418.31369030033 1.0886810268134972 1.149053439250552 1.098911320511563 1.1308985418233228 0.9658651756292964 1.032286897256577 1.0769026391890026 1.2719528101935698 1.119329164694808 1.0 16.526779096209147 -10.149856893191519 9.478132986520276 1.0000063457312742 1.103750407939425 0.14659022155673918 0.07510979163570923 0.0 0.0 0.07885561914239853 0.019125296876328655 7.081791020056055e-11 10.149856893191519 0.10374406220815069 GADNDGSGSESGYTT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 GADNDGSGSESGYTTPK 17 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 GADNDGSGSESGYT(0.005)T(0.995)PK 184.21 9.0778e-08 23921000.0 55567.0 39512.0 38695.0 47881.0 43399.0 34134.0 31602.0 31944.0 36304.0 39012.0 True False 54774.604390260196 39420.51239161005 35513.64646701949 51402.328466333674 40846.356145716876 32674.16839024034 33238.196930226455 33428.23485730534 32215.061221931952 45755.17221977756 1.1971237727433142 0.8615531420635901 0.7761668188338455 1.1234211559609242 0.8927156027195793 0.7141087401724828 0.7264358392221137 0.7305892041393315 0.7040747451936608 1.0 15.481647216149506 -6.5956636942160625 5.011778517791614 0.7566941793140545 0.9701102439017336 0.34253995407052595 0.13792251193292107 0.23401452341715404 10.915060604028332 0.04541933243373378 0.045596330904352875 2.5370925251568266e-07 6.5956636942160625 0.21341606458767914 GADNDGSGSESGYTT(ph)PKK ddPTM_PC-9_AZD4547_30min_R2 2 GADNDGSGSESGYTTPKK 18 1 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 GADNDGSGSES(0.003)GY(0.001)T(0.077)T(0.919)PKK;GADNDGS(0.001)GS(0.003)ES(0.053)GYT(0.038)T(0.904)PKK 88.09 0.0013383 13713200.0 41950.0 31213.0 37961.0 58315.0 54821.0 44089.0 44835.0 42857.0 41942.0 55012.0 True False 55289.227385794446 41301.9918465174 37457.61233672325 44871.37770776876 47210.050429340896 41332.10786027959 48825.22814309622 36234.43540588683 44158.96849370993 53086.0466243496 1.0415020688399557 0.7780197334862929 0.7056018430188042 0.8452574746296343 0.88931185182071 0.7785870391283066 0.9197375063280937 0.6825604412076667 0.831837578831026 1.0 15.696045085942082 GADNDGSGSESGYTT(ph)PKK ddPTM_PC-9_Lapatinib_30min_R1 2 GADNDGSGSESGYTTPKK 18 1 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 GADNDGS(0.001)GS(0.001)ES(0.211)GY(0.003)T(0.211)T(0.573)PKK;GADNDGSGSES(0.004)GYT(0.012)T(0.984)PKK 97.57 0.00064907 15681000.0 44090.0 36181.0 38225.0 40045.0 39375.0 37207.0 31460.0 32840.0 39749.0 36791.0 True False 43461.26851488424 36097.22511745402 35082.288052767064 42990.04288620396 37059.039914228495 35615.74334375323 33088.844865037776 34365.866288314166 35272.049044473715 43150.275329074015 1.007207212084709 0.8365468086163577 0.8130258216250393 0.9962866414722019 0.8588366964430159 0.8253885536567103 0.7668281282725212 0.796422873926808 0.8174234990502582 1.0 15.397082144391048 -6.516230933419558 20.551477328713517 0.8258701434200291 0.9039934585696366 0.1326025338794833 0.08169526179869466 53.50065912668908 165401.42624495295 0.025805074558212553 0.026880394236012167 3.046274721035897e-07 6.516230933419558 0.07812331514960758 GADPES(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 GADPESPR 8 0 Q68DA7-3;Q68DA7-5 Q68DA7-3 1 GADPES(1)PR 95.775 0.017296000000000002 0.0 28988.0 33440.0 23820.0 22310.0 33914.0 26073.0 35375.0 36753.0 30922.0 30244.0 True False 28574.625804251853 33362.57173454748 21861.611547859025 23950.751823978273 31919.245197489403 24957.91856913156 37206.54440879565 38460.67855342301 27439.238736904495 35471.635102403154 0.8055626903513101 0.9405422568830837 0.616312484179167 0.6752085646696236 0.8998526598884334 0.7036021456885335 1.0489097641364427 1.0842657363380848 0.7735543810622231 1.0 15.114378213903699 -7.262510871290534 24.999771224340307 0.9837046188630324 0.7752344697426556 0.408792444110769 0.11956657375924351 100.91633479016566 2354508.231532023 0.04871034337958369 0.03497614107205664 5.463728728658402e-08 7.262510871290534 -0.20847014912037676 GADS(ph)GEEKEEGINR ddPTM_PC-9_AZD4547_30min_R2 1 GADSGEEKEEGINR 14 1 Q9BVG4 Q9BVG4 PBDC1 Protein PBDC1 1 GADS(1)GEEKEEGINR 132.65 6.0835e-05 7588700.0 18258.0 14648.0 11173.0 11660.0 12028.0 13661.0 16572.0 16911.0 17916.0 13177.0 True False 24063.664210007988 19382.67954274778 11024.838719691492 8971.967145204217 10358.119818392819 12806.775510428452 18046.8758957821 14297.79352612065 18863.003183761084 12715.677240766643 1.8924406269812777 1.5243135835979411 0.8670272539118641 0.7055831140821947 0.8145944271992481 1.007164248347681 1.4192618728889688 1.1244224947989179 1.4834446350435844 1.0 13.634320681992413 -7.249327108095214 24.43142958896066 1.2671508042545307 1.1065858337580206 0.023239574596228274 0.3559580190839877 2384.834686934574 4810408.684216346 0.15121149846651394 0.11618444862692624 5.632132870353724e-08 7.249327108095214 -0.1605649704965102 GADS(ph)GEEKEEGINR ddPTM_PC-9_Lapatinib_30min_R1 1 GADSGEEKEEGINR 14 1 Q9BVG4 Q9BVG4 PBDC1 Protein PBDC1 1 GADS(1)GEEKEEGINR 176.56 0.00048426 12908000.0 9877.9 9411.5 11388.0 10315.0 12153.0 12112.0 10983.0 12634.0 10611.0 10030.0 True False 9737.039334614994 9389.708249990832 10451.722598951244 11073.59950983129 11438.184433717295 11593.997994451027 11551.645999768274 13221.021762684573 9415.877441216395 11763.672135865087 0.827721074011295 0.79819533743749 0.888474489788442 0.9413386723071019 0.9723311140952794 0.9855764306030974 0.9819761947079104 1.1238856039158316 0.8004199141617748 1.0 13.522050860237536 -5.649589235287093 1.5044225344668194 0.9850615643791764 0.8063284905800143 0.4328363114019643 0.07398501812448197 0.371283252495421 1.655129850037306 0.022586272337101566 0.0599355980901457 2.2408395690429535e-06 5.649589235287093 -0.17873307379916203 GADTAPTLAPEALPS(ph)QGEVER ddPTM_PC-9_AZD4547_30min_R2 1 GADTAPTLAPEALPSQGEVER 21 0 Q8IZL8;C9JFV4 Q8IZL8 PELP1 Proline-, glutamic acid- and leucine-rich protein 1 1 GADTAPTLAPEALPS(1)QGEVER 166.91 1.0228e-31 0.0 6649.1 6553.3 7978.5 6171.6 5304.8 9332.8 8476.8 9632.6 7774.6 5633.5 True False 8763.375490128386 8671.526068233821 7872.699876940713 4748.8329702694955 4568.320087513316 8749.218540643185 9231.21877826247 8144.103005127418 8185.549483839526 5436.272879703946 1.612019058654324 1.5951233979825648 1.4481796722039184 0.8735457316719745 0.8403404664561471 1.6094148940366766 1.6980786252888012 1.4981041580037346 1.5057282194938866 1.0 12.408402160251354 GADTAPTLAPEALPS(ph)QGEVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GADTAPTLAPEALPSQGEVER 21 0 Q8IZL8;C9JFV4 Q8IZL8 PELP1 Proline-, glutamic acid- and leucine-rich protein 1 1 GADTAPTLAPEALPS(1)QGEVER 182.0 2.4998e-13 2747500.0 7591.0 12392.0 10120.0 8996.3 8186.6 7018.1 8852.1 5906.8 6907.6 6277.7 True False 8876.006370915864 13622.195864125082 10361.299180313721 8492.266477398123 6582.494497999827 6650.058481341041 8013.565004345918 5751.752758771929 7008.610582104692 7415.797315754144 1.196905200208162 1.8369158816120885 1.39719287611895 1.1451589243623372 0.8876313925160757 0.8967422110113009 1.0806073390546793 0.775608139471785 0.9450919818447002 1.0 12.856386098265183 -5.851435420836205 2.4369859460097385 0.9277746870812481 1.5335014011885961 0.690406769802766 0.16375845781809342 0.1440067206703727 1.7396699730695446 0.046851669860547104 0.0801347813237213 1.4078765626629437e-06 5.851435420836205 0.605726714107348 GAEAANVTGPDGVPVEGSR ddPTM_PC-9_Lapatinib_30min_R1 2 GAEAANVTGPDGVPVEGSR 19 0 P16989-2;P16989;P16989-3;A0A0D9SEI8 P16989-2 YBX3 Y-box-binding protein 3 0 ; 159.14 4.425399999999999e-05 6385300.0 20995.0 20106.1 18636.3 21821.0 24413.0 27114.0 19861.0 19009.6 21328.0 21889.5 False True 20695.60744998853 20059.545560765095 17104.095352198357 23425.789132722104 22977.0753378047 25954.39742582109 20889.305399380646 19892.85541395667 18925.81604620331 25673.070909074668 0.8061212280870244 0.7813457779090479 0.6662270911327779 0.9124654084308155 0.8949874138229014 1.0109580391743078 0.8136660188944088 0.7748529766622168 0.7371855168098957 1.0 14.647968255139839 -5.77630533800107 24.99984228556744 0.8719504459696443 0.7542427826532665 0.2940465634340378 0.08947138302375046 330.30999000987356 555476.10313345 0.026842874490591244 0.03999669400756661 1.6737656932838445e-06 5.77630533800107 -0.11770766331637783 GAEAANVTGPGGVPVQGSK ddPTM_PC-9_Lapatinib_30min_R1 2 GAEAANVTGPGGVPVQGSK 19 0 H0Y449;P67809 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 ; 231.21 3.630699999999999e-35 21094100.0 67987.0 72287.0 71692.0 74937.0 73133.0 70618.0 80788.0 67830.0 66237.0 74903.0 False True 67017.49291271133 72119.62389280018 65797.76049912303 80448.11696250393 68831.46072501015 67597.83275859822 84970.80734128001 70981.62942558905 58776.69155346815 87849.88374802632 0.7628637632001076 0.8209415973691652 0.7489794828624492 0.9157452865076936 0.7835122573688842 0.7694698031984238 0.9672273168282822 0.807987744516324 0.6690582735664538 1.0 16.422752756662362 -11.862390374119318 2.4911017033593588 2.3297938367801256 0.810330002281069 0.3458250084019161 0.08013153092183309 5660716.634976511 1867991.4544716321 44247151.968049385 0.019743895796262744 1.3728074453375454e-12 11.862390374119318 -1.5194638344990565 GAEADQIIEYLK ddPTM_PC-9_Lapatinib_30min_R1 1 GAEADQIIEYLK 12 0 D6R937;A0A5F9ZHC5;Q12904;Q12904-2 D6R937 AIMP1 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1;Endothelial monocyte-activating polypeptide 2 0 140.24 0.00015721 0.0 5471.2 7412.9 7942.5 8267.8 7525.0 7206.7 8225.3 6812.7 6543.2 7209.1 False True 5393.179684704799 7395.735885497216 7289.498308936617 8875.841592572282 7082.394294719222 6898.486240638221 8651.165787297998 7129.242912984106 5806.235913049395 8455.18332947806 0.6378548488596427 0.874698465698881 0.8621336788195458 1.0497515247987164 0.8376393531323251 0.8158884286503182 1.0231789720202358 0.843180169509606 0.6867072760925947 1.0 13.045620320865819 -4.758133671949171 4.831951150619366 0.8889701615452088 0.6194217119848358 0.3439417411977135 0.10387422489552342 0.22205823108843978 12.776381171108302 0.02585493372921972 0.20617162445704065 1.7452848871957733e-05 4.758133671949171 -0.26954844956037305 GAEAFGDS(ph)EEDGEDVFEVEK ddPTM_PC-9_AZD4547_30min_R2 1 GAEAFGDSEEDGEDVFEVEK 20 0 Q99549-2;Q99549 Q99549-2 MPHOSPH8 M-phase phosphoprotein 8 1 GAEAFGDS(1)EEDGEDVFEVEK 98.12100000000001 0.0007349 0.0 2193.8 3085.4 3701.7 3828.6 4552.8 3720.3 2387.1 3335.1 2218.5 3900.6 True False 2891.38276612529 4082.6952117145015 3652.6130393521885 2945.9754212803496 3920.722307048452 3487.669052883897 2599.5472755745486 2819.7369279738 2335.7653808424852 3764.0411812502402 0.7681591743810057 1.0846574240610245 0.9703966730084923 0.7826629092038342 1.0416257735379424 0.9265756895160895 0.6906266829713854 0.7491248879049761 0.6205472438711874 1.0 11.87806669691039 -7.2473074168775184 21.05293875348735 0.7441684806858424 0.9364353875039365 0.26872335256834456 0.13033476376959102 110.4349783562006 164519.31224900406 0.04767676555029974 0.03663267432935781 5.6583861639012545e-08 7.2473074168775184 0.1922669068180941 GAEETSWS(ph)GEER ddPTM_PC-9_AZD4547_30min_R2 2 GAEETSWSGEER 12 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 GAEET(0.002)S(0.147)WS(0.851)GEER;GAEET(0.002)S(0.01)WS(0.988)GEER 116.84 0.00065837 141894000.0 102164.0 88456.0 141889.0 162484.0 137964.0 134692.0 74142.0 135315.0 96743.0 114132.0 True False 134650.02685678893 117047.67214864137 140007.4591513744 125025.82415277556 118810.08003198759 126269.68794748741 80740.49436791425 114405.17597936354 101856.6374752511 110136.27341907701 1.2225765651651859 1.0627531558405463 1.2712202329439206 1.1351920695286526 1.0787552215418263 1.1464859308161037 0.733096298443751 1.0387601870642837 0.9248237144149479 1.0 16.748930173704004 -7.1556706820325084 11.77192383146557 0.9274534434989019 1.1502442579373813 0.5868344413004115 0.09396664327174938 0.4505985921647771 47.87603819964709 0.034410612947554736 0.02665450204421756 6.98762062379794e-08 7.1556706820325084 0.22279081443847937 GAEETSWS(ph)GEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GAEETSWSGEER 12 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 GAEET(0.004)S(0.029)WS(0.966)GEER;GAEETS(0.003)WS(0.997)GEER 155.86 0.00034048 112632000.0 53266.0 53191.0 54347.0 84750.0 65727.0 59278.0 53017.0 54507.0 45798.0 47389.0 True False 62282.881748544925 58471.45095292749 55642.83859214529 80001.7322632071 52848.26617521736 56169.35732704499 47994.84595015955 53076.24900494036 46467.70910869635 55980.25056888238 1.1125866911207785 1.0445014153871952 0.9939726604774318 1.4291063625155955 0.9440519761552123 1.0033780977441307 0.8573531819244543 0.9481245343771958 0.8300732604174204 1.0 15.772630324010741 -6.481858553887437 24.999421693280034 0.9260939672354429 1.1345084006540986 0.43879364543827515 0.11873736911746391 499.0621063478872 304149.4802685884 0.036760725347270234 0.04167791683328688 3.297170808119196e-07 6.481858553887437 0.20841443341865573 GAEETSWS(ph)GEER ddPTM_PC-9_Lapatinib_30min_R1 2 GAEETSWSGEER 12 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 GAEET(0.005)S(0.044)WS(0.952)GEER;GAEET(0.001)S(0.019)WS(0.981)GEER 133.98 5.5997e-05 174300000.0 55061.0 45677.0 69576.0 43454.0 54517.0 65899.0 44547.0 53778.0 57533.0 42839.0 True False 54275.820043049236 45571.23771288649 63855.729851126685 46649.7521182946 51310.41724454586 63080.653388072045 46853.42568985496 56276.722206241146 51053.027690651514 50243.66407062054 1.080252028728662 0.9070046652814437 1.2709210411361231 0.9284703450911844 1.0212315959366722 1.2554946888309804 0.9325240616209758 1.1200759985804531 1.0161087698320201 1.0 15.616654057627727 -8.50198952914824 21.985871935458572 0.9999999078573917 1.0624923415482639 0.03457412528440862 0.12043929127829764 556.2958169080404 585498.884981381 0.10943204517940604 0.028255232576983102 3.147824207313595e-09 8.50198952914824 0.06249243369087221 GAES(ph)ENEEESPR ddPTM_PC-9_AZD4547_30min_R2 3 GAESENEEESPR 12 0 Q9UEG4 Q9UEG4 ZNF629 Zinc finger protein 629 1 GAES(1)ENEEESPR;GAES(1)ENEEESPR;GAES(0.998)ENEEES(0.002)PR 139.74 0.00011597 0.0 7182.71 10294.099999999999 10729.7 10159.599999999999 11084.3 10845.8 10097.699999999999 15357.0 11314.2 8970.0 True False 9466.662370350887 13621.466512902776 10587.417167338559 7817.461184255299 9545.43627394508 10167.610411463646 10996.375738163091 12983.928518753162 11912.245513602906 8655.963030255514 1.093657902334114 1.5736511888152884 1.2231356730997995 0.9031301493468297 1.1027584383829456 1.1746365339043632 1.2703815508138199 1.4999981484867653 1.376189509124009 1.0 13.07947862206839 -7.474268016116602 5.431999108895246 1.3389748500593617 1.184549876024633 0.05188471789819016 0.19739066340309416 0.49281074640257383 34.12004757795222 0.09036438456191458 0.05837132312911998 3.355304844372655e-08 7.474268016116602 -0.15442497403472877 GAES(ph)ENEEESPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GAESENEEESPR 12 0 Q9UEG4 Q9UEG4 ZNF629 Zinc finger protein 629 1 GAES(0.686)ENEEES(0.314)PR;GAES(1)ENEEESPR 140.82 7.6589e-05 1944300.0 11805.900000000001 18096.8 14260.5 12317.2 15524.5 10362.3 13608.3 10194.599999999999 9094.099999999999 9001.7 True False 13804.40569284621 19893.330706415327 14600.524403247407 11627.107216901193 12482.585668555726 9818.8827462134 12319.223308439869 9927.002552071566 9227.084008153091 10633.63695258201 1.298182903403928 1.8707927301942466 1.3730508638159005 1.0934271377468792 1.1738773595730823 0.9233795351485292 1.1585145668762533 0.9335472516448041 0.8677260705155647 1.0 13.37634749627275 -5.677106535204828 2.7092459612452573 1.0184952759508181 1.5942822540431694 0.6783750927544447 0.15957917475134237 0.14209835276422983 2.1030578572132717 0.04420507338487681 0.08488903007954368 2.1032624327971172e-06 5.677106535204828 0.5757869780923512 GAES(ph)ENEEESPR ddPTM_PC-9_Lapatinib_30min_R1 1 GAESENEEESPR 12 0 Q9UEG4 Q9UEG4 ZNF629 Zinc finger protein 629 1 GAES(1)ENEEESPR 115.24 0.00073184 1377300.0 5107.3 6308.8 6830.2 5909.7 5212.9 6594.9 6262.4 7782.6 5689.4 5272.2 True False 5034.468965435885 6294.192361211518 6268.6473213344525 6344.319052181282 4906.287470955722 6312.851500462766 6586.636429841469 8144.208007778135 5048.5998599619825 6183.492745235085 0.8141788424212801 1.0179024413122724 1.0137712745219902 1.0260089747934333 0.7934492160173455 1.0209200140692918 1.0651967587278308 1.3170886331279277 0.8164641033746445 1.0 12.59420625917231 -6.992540723320636 24.986905804243023 1.0713895836279623 0.943399203692976 0.13415977740788654 0.13674797357162485 328.50482749526645 1100411.7326463342 0.04705704058722371 0.041415998783429636 1.0173239683473184e-07 6.992540723320636 -0.1279903799349863 GAES(ph)PFEEK ddPTM_PC-9_AZD4547_30min_R2 4 GAESPFEEK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 GAES(1)PFEEK;GAES(1)PFEEK;GAES(1)PFEEK;GAES(1)PFEEK 172.21 0.00070245 1330220000.0 284536.0 299204.0 391800.0 445930.0 439436.0 393680.0 381173.0 414522.0 364911.0 409237.0 True False 375012.529283537 395915.8417468803 386604.4760024276 343127.7280498213 378427.89661749813 369063.127365893 415096.6585700543 350467.1496679432 384199.4504794284 394909.7371920481 0.9496158082857428 1.002547682318461 0.9789692164881171 0.8688763424512757 0.958264284158345 0.9345505886739235 1.0511178111776693 0.8874614036105873 0.9728791526165605 1.0 18.59116341484964 GAES(ph)PFEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GAESPFEEK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 GAES(1)PFEEK;GAES(1)PFEEK;GAES(1)PFEEK;GAES(1)PFEEK;GAES(1)PFEEK 189.17 7.1595e-05 864252000.0 409319.0 477523.0 489442.0 631250.0 668510.0 618634.0 604790.0 624970.0 542714.0 457157.0 True False 478608.62228124205 524928.3276004351 501112.1534991221 595883.109040114 537520.2644391892 586191.7439970844 547499.9128995785 608565.1997104511 550650.1655359837 540035.9452471797 0.886253269793325 0.972024792461121 0.9279237019486882 1.1034137899235068 0.9953416419219298 1.0854680121871865 1.0138212423044959 1.126897579811849 1.0196546551803063 1.0 19.042695911905426 -5.747314919241876 24.999253623595965 1.0523049667592383 0.9330629541390699 0.5850366330477603 0.04641036448181097 155.08732279437302 274490.83235620765 0.01166349715998593 0.020073202966008473 1.7893079056100367e-06 5.747314919241876 -0.11924201262016842 GAES(ph)PFEEK ddPTM_PC-9_Lapatinib_30min_R1 6 GAESPFEEK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 GAES(1)PFEEK;GAES(1)PFEEK;GAES(1)PFEEK;GAES(1)PFEEK;GAES(1)PFEEK;GAES(1)PFEEK 193.3 9.1658e-05 1753246600.0 1173900.0 1041543.0 1031140.0 987277.0 944962.0 857159.0 889426.0 855077.0 895230.0 673054.0 True False 1157159.9707331057 1039131.3711757117 946363.649515504 1059884.6440395273 889381.193026772 820500.3077052206 935476.1262851588 894806.9990320574 794399.7702101743 789390.4871119185 1.4658904428487816 1.3163717933535033 1.198853628168096 1.3426620428594784 1.1266682428371815 1.0394099258874037 1.1850613119341131 1.1335416547845896 1.0063457606596995 1.0 19.590379607958234 -1.5228787452816692 0.23126188215769583 1.0053286198753049 3.5135410363886415 0.7808522235016226 0.06855743668996715 24.39299023255079 0.3201598308665912 0.1026333402856988 23.19994226078001 0.029999999999908013 1.5228787452816692 2.5082124165133366 GAFMLEPEGMSPMEPAGVS(ph)PMPGTQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GAFMLEPEGMSPMEPAGVSPMPGTQK 26 0 E5RJN3;A0A0A6YYG7;Q6IBW4-2;Q6IBW4;Q6IBW4-4;Q6IBW4-5 E5RJN3 NCAPH2 Condensin-2 complex subunit H2 1 GAFMLEPEGMS(0.004)PMEPAGVS(0.993)PMPGT(0.003)QK 75.956 0.00050801 4745500.0 50648.0 40880.0 45676.0 52686.0 63266.0 59121.0 55612.0 58352.0 50579.0 43757.0 True False 59221.706056401876 44938.29623349201 46765.08906719464 49734.174230316654 50869.48145878105 56020.59068342769 50344.02876398651 56820.32182905461 51318.62218893297 51689.79771977856 1.145713635357124 0.8693842540671588 0.9047257124262351 0.9621661609112159 0.9841300160344093 1.0837842892542797 0.9739645149495894 1.0992560299247003 0.99281917230828 1.0 15.657591936075228 -6.553055690703447 10.242512166475406 1.032866191056085 0.9603796452649844 0.11625143160463758 0.07673540878905877 0.767577101481699 252.80375428097366 0.024554815322215075 0.024624241524069064 2.798622422040041e-07 6.553055690703447 -0.07248654579110059 GAFT(ph)FQGSMIDMPLLK ddPTM_PC-9_AZD4547_30min_R2 1 GAFTFQGSMIDMPLLK 16 0 Q5JVB9;Q5JVC0;Q8N0X4-2;Q8N0X4 Q5JVB9 CLYBL Citrate lyase subunit beta-like protein, mitochondrial 1 GAFT(0.5)FQGS(0.5)MIDMPLLK 68.044 0.023901 4655800.0 11032.0 12906.0 10739.0 14636.0 12577.0 11722.0 10764.0 13706.0 10212.0 14462.0 True False 14539.946520145051 17077.612109414462 10596.59384326205 11261.896323945879 10830.90064482262 10989.021486951342 11721.975147368958 11588.052632547422 10751.785471788806 13955.689781890209 1.0418651279432287 1.2237024737806552 0.7593027653146077 0.8069752552510899 0.7760921039444059 0.7874223100897094 0.8399423697838382 0.8303461035358365 0.7704230775995757 1.0 13.768565813184429 -5.265542530223322 24.999419523089472 0.8125817835292228 1.132783810727001 0.7226686531331302 0.07702865440707478 141.85150739739484 864269.1476001987 0.01835078790081999 0.04053353724262417 5.425721149339853e-06 5.265542530223322 0.3202020271977781 GAGAAGLPQPPRES(ph)PQLHER ddPTM_PC-9_AZD4547_30min_R2 1 GAGAAGLPQPPRESPQLHER 20 1 Q9BR39 Q9BR39 JPH2 Junctophilin-2 1 GAGAAGLPQPPRES(1)PQLHER 76.158 0.00092787 3210600.0 22211.0 28672.0 27350.0 31046.0 29075.0 29685.0 23637.0 34010.0 27169.0 27474.0 True False 29273.63598250016 37939.66328848063 26987.32112982745 23888.824355918525 25038.438121031853 27828.79225730682 25740.647209063554 28754.535972051523 28605.09787338719 26512.14362243478 1.1041595277768705 1.4310296379194247 1.0179230134748731 0.9010521629682036 0.9444139439499767 1.049662096495203 0.9709002627490906 1.0845798205362471 1.0789432299688257 1.0 14.69436570265647 -5.350819027088296 8.449335923585084 1.00264229394456 1.2668736474374986 0.5688733979036783 0.09112038107671735 0.20046652202638218 17.2169865200924 0.02327121824967781 0.04862030743225887 4.4584199451815185e-06 5.350819027088296 0.2642313534929386 GAGAAGLPQPPRES(ph)PQLHER ddPTM_PC-9_Lapatinib_30min_R1 1 GAGAAGLPQPPRESPQLHER 20 1 Q9BR39 Q9BR39 JPH2 Junctophilin-2 1 GAGAAGLPQPPRES(1)PQLHER 47.903999999999996 0.027932 4533200.0 31411.0 41612.0 26137.0 14711.0 26463.0 22743.0 24899.0 20544.0 27844.0 13031.0 True False 30963.07337992807 41515.64997063363 23988.116751737678 15792.896014457394 24906.49836825977 21770.334906522432 26188.14838825734 21498.54923955926 24707.915509681414 15283.390987283938 2.0259295470285306 2.7163899690307876 1.5695546081164993 1.033337171547687 1.6296447816444948 1.4244440206126867 1.7135037904903672 1.4066609470009925 1.6166514047987683 1.0 13.899677054976545 -5.36228345129542 5.947526114090543 1.434972650375341 2.364472152612812 0.659925173814554 0.2729137495811722 0.11909881393559522 5.763021936178857 0.06771107646675643 0.14372749551921185 4.342267245934897e-06 5.36228345129542 0.9294995022374708 GAGAELKDTQS(ph)PSTCSEGLLGWSQK ddPTM_PC-9_AZD4547_30min_R2 2 GAGAELKDTQSPSTCSEGLLGWSQK 25 1 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 GAGAELKDT(0.006)QS(0.969)PS(0.016)T(0.006)CS(0.002)EGLLGWSQK;GAGAELKDT(0.008)QS(0.942)PS(0.046)T(0.003)CSEGLLGWSQK 121.35 1.5969e-09 29463000.0 172362.0 171013.0 196033.0 253631.0 233033.0 245246.0 194030.0 244066.0 193873.0 216772.0 True False 227169.53064768325 226289.6079085147 193433.4743343133 195160.29150988752 200680.39039237844 229910.72885078235 211298.29411408407 206351.20777873363 204120.7309804259 209182.87826026182 1.0859852992606915 1.0817788233459957 0.9247098803834539 0.9329649402140474 0.95935380592046 1.0990896136572483 1.010112758134967 0.9864631823355778 0.9758003746676739 1.0 17.67440524542942 -5.225893397087422 20.053423973047593 0.9876239143980856 1.0838830574520062 0.4215869747244263 0.04580227936180355 61.11891729464834 34477.676181148054 0.012883068556761485 0.03407171595787632 5.944380528272812e-06 5.225893397087422 0.09625914305392058 GAGAELKDTQS(ph)PSTCSEGLLGWSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GAGAELKDTQSPSTCSEGLLGWSQK 25 1 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 GAGAELKDT(0.008)QS(0.979)PS(0.012)T(0.001)CSEGLLGWSQK 113.42 1.5062e-08 7918500.0 44442.0 31591.0 40301.0 54670.0 61997.0 52875.0 57957.0 55505.0 44163.0 44170.0 True False 51965.1528304891 34727.145702354355 41261.9286823936 51607.0171425314 49849.13289918833 50102.14191888228 52466.89338765676 54048.052562408724 44808.80032681242 52177.67135047237 0.9959270217607874 0.6655556831790265 0.7907966686600715 0.9890632488347757 0.9553728943623514 0.9602218846132676 1.0055430230920372 1.035846391062054 0.8587734785218001 1.0 15.671144938766313 -5.7606676390602 24.999586334064887 0.9738103017234908 0.802239346144971 0.3950518927211891 0.08709783729540468 17.98427169922394 582535.2544604164 0.023042990244433872 0.03708803326107444 1.7351313673268769e-06 5.7606676390602 -0.17157095557851976 GAGAT(ph)SGSPPAGRN ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GAGATSGSPPAGRN 14 1 B4DEE8;P16455 B4DEE8 MGMT Methylated-DNA--protein-cysteine methyltransferase 1 GAGAT(0.686)S(0.247)GS(0.067)PPAGRN 112.44 0.0010375 53577000.0 30384.0 26912.0 28678.0 41276.0 40867.0 44733.0 36662.0 34189.0 32648.0 28324.0 True False 35527.41108864545 29583.645504788088 29361.792281920654 38963.43953859755 32859.404716214165 42387.12273205409 33189.10995010561 33291.574976239855 33125.415236052184 33458.916987339355 1.0618219084045308 0.8841782152118778 0.8775475994345834 1.1645158614470716 0.9820821375852649 1.2668408468837504 0.9919361694421897 0.9949985825553522 0.990032500113098 1.0 15.030103127905942 -5.747156730654517 24.99983339467578 1.0586281820810777 0.9354821436503493 0.2168733414331152 0.09950551820435385 349.0015144642987 610874.2482904496 0.026950619008717275 0.04640546940687852 1.7899597666331268e-06 5.747156730654517 -0.12314603843072836 GAGATS(ph)GSPPAGRN ddPTM_PC-9_AZD4547_30min_R2 2 GAGATSGSPPAGRN 14 1 B4DEE8;P16455 B4DEE8 MGMT Methylated-DNA--protein-cysteine methyltransferase 1 GAGAT(0.014)S(0.493)GS(0.493)PPAGRN;GAGAT(0.069)S(0.687)GS(0.243)PPAGRN 141.73 0.00020386 75489600.0 80329.1 60707.4 97866.3 151112.4 130874.2 102543.6 87055.2 110955.2 71868.3 109116.0 True False 105872.08285092282 80329.87985208955 96568.52891729563 116275.77084330693 112704.57638313132 96131.5324816026 94802.94415173108 93809.62333684729 75667.11161595766 105295.88205232534 1.0054722063899055 0.7628966896556384 0.9171159121807558 1.1042765260803389 1.070360722436651 0.9129657362462794 0.9003480696863345 0.8909144546624329 0.7186141579435741 1.0 16.684089490488404 -7.374662190571465 2.129408470787662 0.8568034505668237 0.9640622189905027 0.1353299662740387 0.10848554876220176 0.6828964076862124 6.046329602736135 0.06125776843364191 0.036098668217901184 4.2202464131111765e-08 7.374662190571465 0.10725876842367899 GAGATS(ph)GSPPAGRN ddPTM_PC-9_Lapatinib_30min_R1 1 GAGATSGSPPAGRN 14 1 B4DEE8;P16455 B4DEE8 MGMT Methylated-DNA--protein-cysteine methyltransferase 1 GAGAT(0.125)S(0.774)GS(0.101)PPAGRN 164.53 0.00021081 65243000.0 108090.0 65567.0 82384.0 74497.0 62718.0 60663.0 55769.0 57729.0 70558.0 57920.0 True False 106548.61677872165 65415.183639924544 75610.70553143663 79975.75789470687 59029.05054833226 58068.584902359864 58656.44594018728 60411.300090075805 62611.01503132091 67931.3948264512 1.5684738558795739 0.9629595241941522 1.113045090927461 1.1773018660815988 0.8689509570521503 0.8548121976695974 0.8634659436927618 0.8892986850102597 0.9216801037469845 1.0 16.05179085670856 -1.522878745280338 0.7543503730871653 0.9186074970134704 106.88585352296589 0.7180636593010574 0.11127655294573728 218.47159563584773 0.9266742587600741 0.04325862422086477 39361.704417498666 0.029999999999999964 1.522878745280338 105.96724602595242 GAGATSGS(ph)PPAGR ddPTM_PC-9_AZD4547_30min_R2 1 GAGATSGSPPAGR 13 0 B4DEE8;P16455 B4DEE8 MGMT Methylated-DNA--protein-cysteine methyltransferase 1 GAGAT(0.005)S(0.024)GS(0.972)PPAGR 89.189 0.026481 0.0 26584.0 30902.0 38198.0 42220.0 30147.0 32684.0 26172.0 40279.0 29226.0 30302.0 True False 35037.159018449594 40890.46717845382 37691.46956187018 32486.831292497598 25961.609425098773 30640.26431321596 28501.257298117835 34054.80606934028 30770.82669393847 29241.136203210972 1.198214692307413 1.3983884516075553 1.288987859429733 1.1109975709127957 0.8878454395437592 1.0478479392962627 0.974697327082253 1.1646197956425757 1.0523129634941997 1.0 14.835711749762199 -5.8419634133705545 3.66541599072624 1.0265819513503454 1.308474200311758 0.6993081406090612 0.08000398061502804 0.12315760759967978 3.23374814769764 0.023308845405812628 0.037163826777961546 1.438919793260908e-06 5.8419634133705545 0.28189224896141263 GAGATSGS(ph)PPAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GAGATSGSPPAGR 13 0 B4DEE8;P16455 B4DEE8 MGMT Methylated-DNA--protein-cysteine methyltransferase 1 GAGAT(0.05)S(0.284)GS(0.666)PPAGR 94.402 0.0037770000000000004 31999000.0 57129.0 70830.0 72487.0 60391.0 58055.0 49360.0 64242.0 39119.0 37058.0 39402.0 True False 66799.81135081705 77861.53430083748 74215.36498847822 57007.4880602637 46679.539501304556 46771.47470668616 58156.5326881972 38092.16770000661 37599.90314315186 46545.27069393961 1.4351578657703385 1.6728130084970239 1.594477030254792 1.224775089076586 1.00288469280258 1.0048598710325258 1.2494616922653203 0.8183896480156548 0.8078136099023165 1.0 15.506346967462056 -5.955455054268721 2.539139611940174 0.9856448853795139 1.583500663477804 0.8076766268402918 0.1278804898245873 0.12359756700521571 1.61343192473254 0.04163777655685444 0.06525215055507488 1.1080132292488264e-06 5.955455054268721 0.59785577809829 GAGATSGS(ph)PPAGRN ddPTM_PC-9_AZD4547_30min_R2 1 GAGATSGSPPAGRN 14 1 B4DEE8;P16455 B4DEE8 MGMT Methylated-DNA--protein-cysteine methyltransferase 1 GAGAT(0.002)S(0.208)GS(0.79)PPAGRN 153.32 0.00038451 77313000.0 66779.0 53261.0 87260.0 133010.0 118240.0 89812.0 64824.0 103610.0 67188.0 78161.0 True False 88013.33291051179 70476.57667437803 86102.87538532878 102346.5994840148 101824.41697096515 84196.04144225153 70593.21041927206 87599.45522094246 70739.42051297949 75424.60718035694 1.1669047569588586 0.9343976628987 1.1415753903687922 1.356939111917168 1.3500158738312076 1.1162940662179408 0.935944024878619 1.1614174537425535 0.9378825181525423 1.0 16.202747657226674 -7.004754316219901 24.943788333047767 1.0228133809025353 1.1874360240487647 0.31596139087403585 0.12498308807009986 302.15905815897554 1585299.101387747 0.04946232660676955 0.042497499871412193 9.891124850736816e-08 7.004754316219901 0.16462264314622943 GAGATSGS(ph)PPAGRN ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GAGATSGSPPAGRN 14 1 B4DEE8;P16455 B4DEE8 MGMT Methylated-DNA--protein-cysteine methyltransferase 1 GAGAT(0.018)S(0.361)GS(0.62)PPAGRN;GAGAT(0.122)S(0.368)GS(0.51)PPAGRN;GAGAT(0.173)S(0.128)GS(0.699)PPAGRN 164.22 0.00020082 70530100.0 77541.4 56895.4 72580.7 89323.0 99967.2 99057.7 90307.2 82408.9 81669.5 76225.1 True False 90667.6275075401 62543.59930340076 74311.29915183756 84318.52189907314 80379.34478054979 93862.93983088549 81752.64824849104 80245.75369444699 82863.76193398576 90044.10723244036 1.0069246094415727 0.6945884769777367 0.8252766498090759 0.9364135476562928 0.892666352647132 1.0424106886704665 0.9079178056311258 0.8911827343381855 0.9202574658226194 1.0 16.45834424430165 -5.7626971039022825 22.411865574882402 0.9377801775600333 0.8274957115679403 0.2215481735742343 0.08371982482367213 11.803418355087432 210364.02691708042 0.02247793542396528 0.0355780419001284 1.7270419871865225e-06 5.7626971039022825 -0.11028446599209296 GAGATSGS(ph)PPAGRN ddPTM_PC-9_Lapatinib_30min_R1 1 GAGATSGSPPAGRN 14 1 B4DEE8;P16455 B4DEE8 MGMT Methylated-DNA--protein-cysteine methyltransferase 1 GAGATS(0.024)GS(0.976)PPAGRN 173.59 0.00020864 61789000.0 130370.0 79662.0 103600.0 84900.0 74564.0 87372.0 61288.0 67587.0 89682.0 50868.0 True False 128510.89989306989 79477.54753341858 95082.40790756469 91143.82921809734 70178.29211846438 83635.30323407978 64461.19275551287 70727.33875847407 79581.0687666731 59660.46602265058 2.154037815331172 1.332164376712114 1.5937255312666494 1.5277089720266992 1.1762947358108236 1.4018546754617531 1.0804674695474161 1.1854975911790877 1.333899549769851 1.0 15.864487626514245 -1.5228787452803376 0.42598675395897556 1.1753213995935874 16.860203792486846 0.6930117473748286 0.17388719931830474 47.122147863986996 0.5969399981990181 0.11272290731369858 632.5432755526006 0.029999999999999995 1.5228787452803376 15.68488239289326 GAGDGS(ph)DEEVDGK ddPTM_PC-9_AZD4547_30min_R2 2 GAGDGSDEEVDGK 13 0 P35579;P35579-2 P35579 MYH9 Myosin-9 1 GAGDGS(1)DEEVDGK;GAGDGS(1)DEEVDGK 174.94 5.4851999999999996e-05 135616000.0 106904.0 120006.0 112329.0 111226.0 113689.0 119521.0 116549.0 120991.0 98253.0 89485.0 True False 140897.24825866419 158795.59265476462 110839.44406553528 85584.56412456975 97905.24476498696 112047.33297576425 126921.63521467001 102294.62104658886 103446.45299252491 86352.15738711419 1.6316586929846577 1.8389302301144446 1.283574694823724 0.9911108965222103 1.1337903733670558 1.2975626361419015 1.46981429364508 1.1846214865021272 1.1979602608974491 1.0 16.397944601458953 -5.33676228502788 5.2770844679192646 1.2011511428264137 1.733803083409893 0.7067453143369351 0.13977706216242095 0.11233052275228331 5.6137993255927645 0.038794518057521626 0.08414364238576165 4.6050856809618295e-06 5.33676228502788 0.5326519405834793 GAGDGS(ph)DEEVDGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GAGDGSDEEVDGK 13 0 P35579;P35579-2 P35579 MYH9 Myosin-9 1 GAGDGS(1)DEEVDGK 177.21 0.00014113 31924000.0 32245.0 59149.0 41107.0 49739.0 37930.0 39035.0 45908.0 31528.0 47578.0 41567.0 True False 37703.44163221998 65020.92181787721 42087.14677916562 46952.285086013704 30497.88878278325 36987.93588280981 41559.26189486251 30700.423406677273 48273.73824126718 49102.768055809036 0.7678475801887004 1.324180375004032 0.857123711056989 0.9562044451882805 0.6211032491716165 0.7532759831537441 0.8463730974927369 0.6252279580610182 0.9831164342181361 1.0 15.583516735002359 -5.753146274278865 2.2275653059199865 0.7900459133908619 1.0411114112631712 0.15706891569209502 0.18129745924245452 0.41210823969801935 4.170112823983601 0.050883274503106854 0.0971989311017727 1.765443103458402e-06 5.753146274278865 0.25106549787230925 GAGDGS(ph)DEEVDGK ddPTM_PC-9_Lapatinib_30min_R1 4 GAGDGSDEEVDGK 13 0 P35579;P35579-2 P35579 MYH9 Myosin-9 1 GAGDGS(1)DEEVDGK;GAGDGS(1)DEEVDGK;GAGDGS(1)DEEVDGK;GAGDGS(1)DEEVDGK 212.11 9.148100000000001e-11 226156800.0 115354.0 187451.0 150615.0 142029.0 190241.0 175072.0 180772.0 175102.0 165886.0 150722.0 True False 113709.03080666704 187016.9687264551 138232.01609071277 152474.28645485445 179051.3984081965 167584.57867276476 190131.48963581093 183237.87816127887 147202.17182297827 176774.09687555913 0.6432448691094883 1.0579432848586774 0.7819698617270933 0.8625374936136111 1.0128825522114842 0.9480154707888941 1.0755619346744834 1.0365652061018304 0.8327134711744666 1.0 17.431547363153598 -6.215584612200694 6.231234917746431 0.9888609818111065 0.8473029113243571 0.29027994250597167 0.11268974397431925 0.2953292734192207 29.653814671964536 0.03211117803502438 0.04122620919290604 6.087169398393373e-07 6.215584612200694 -0.1415580704867494 GAGDGS(ph)DEEVDGKADGAEAKPAE ddPTM_PC-9_AZD4547_30min_R2 4 GAGDGSDEEVDGKADGAEAKPAE 23 2 P35579;P35579-2 P35579 MYH9 Myosin-9 1 GAGDGS(1)DEEVDGKADGAEAKPAE;GAGDGS(1)DEEVDGKADGAEAKPAE;GAGDGS(1)DEEVDGKADGAEAKPAE;GAGDGS(1)DEEVDGKADGAEAKPAE 74.665 0.0011814 482434000.0 229066.0 202815.0 201142.0 290977.0 252958.0 234301.0 222996.0 225811.0 218178.0 250435.0 True False 301904.223131213 268370.9824865092 198474.72565615183 223896.74819983626 217839.1480729144 219650.12143099992 242842.21199950675 190917.09857056485 229710.44366078512 241667.3468764813 1.2492553381053975 1.11049749151124 0.8212724152493566 0.9264666952059197 0.901400834198152 0.9088944959670757 1.0048614971704306 0.789999563607344 0.9505232983676216 1.0 17.882663029535415 -5.048840423074762 3.830919982716738 0.9092556288883696 1.2309179470625264 0.7406895118443313 0.06539870561955453 0.09605867663174307 2.8508401524414073 0.016074994245503845 0.05773561239397684 8.936337797189945e-06 5.048840423074762 0.3216623181741568 GAGDGS(ph)DEEVDGKADGAEAKPAE ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GAGDGSDEEVDGKADGAEAKPAE 23 2 P35579;P35579-2 P35579 MYH9 Myosin-9 1 GAGDGS(1)DEEVDGKADGAEAKPAE;GAGDGS(1)DEEVDGKADGAEAKPAE;GAGDGS(1)DEEVDGKADGAEAKPAE;GAGDGS(1)DEEVDGKADGAEAKPAE 59.011 0.017888 92893000.0 155368.0 133684.0 118428.0 191860.0 172608.0 150522.0 167210.0 178309.0 162722.0 150242.0 True False 181668.7337421232 146955.26403322295 121251.7726606908 181110.70621851264 138786.7014768958 142628.36134116302 151370.65830443424 173628.57768400226 165101.50141022043 177479.68528498267 1.0236029743371142 0.8280117456668573 0.683186768479978 1.020458797454478 0.781986407368501 0.803632038856401 0.8528900536496634 0.9783011357339483 0.9302557706540535 1.0 17.437294374457657 -7.756509459314372 23.789936746013723 0.9657088652413264 0.8499454382463294 0.21553459380787143 0.09843002075159808 99.54688567794867 480389.6574894784 0.04753250220236753 0.026286146633630304 1.751824277525201e-08 7.756509459314372 -0.11576342699499698 GAGDGS(ph)DEEVDGKADGAEAKPAE ddPTM_PC-9_Lapatinib_30min_R1 4 GAGDGSDEEVDGKADGAEAKPAE 23 2 P35579;P35579-2 P35579 MYH9 Myosin-9 1 GAGDGS(1)DEEVDGKADGAEAKPAE;GAGDGS(1)DEEVDGKADGAEAKPAE;GAGDGS(1)DEEVDGKADGAEAKPAE;GAGDGS(1)DEEVDGKADGAEAKPAE 68.92699999999999 0.0034764 977653000.0 144882.0 141667.0 102282.0 112016.0 110952.0 114843.0 97512.0 94615.0 106811.0 94157.0 True False 142815.95611189486 141338.97876549457 93872.76877993775 120254.030314422 104426.02150002489 109931.4326021086 102560.69423011967 99011.15830903935 94780.82041030675 110431.91199368362 1.2932489670201808 1.2798744150475159 0.8500511046599192 1.0889427534434084 0.9456145385402522 0.995467982193375 0.9287233407313081 0.8965810382301675 0.8582738331627179 1.0 16.75279760871146 -5.2502001599432955 24.718982654028267 0.9480819094913235 1.2865617718913238 0.8032676892081387 0.06751360226610732 254.65526376305084 560073.04665135 0.01723263960589982 0.044687901906972805 5.620822100548257e-06 5.2502001599432955 0.3384798624000003 GAGGALLT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 GAGGALLTPK 10 0 Q8N1G0;Q8N1G0-2;H0Y5I5 Q8N1G0 ZNF687 Zinc finger protein 687 1 GAGGALLT(1)PK 103.31 0.0070393999999999995 2647500.0 38406.0 40684.0 45389.0 47408.0 48684.0 49357.0 37508.0 46719.0 41713.0 46643.0 True False 50618.30910557384 53834.307381017934 44787.11220335425 36478.81804629858 41925.066947009975 46270.69898749846 40846.13933737596 39499.65204581813 43917.864021222704 45010.04276702424 1.1246003334762078 1.1960510159847841 0.9950470928271741 0.810459528668213 0.9314602779654674 1.028008331984919 0.907489458492608 0.8775741949473731 0.975734776537433 1.0 15.457959315073724 -5.395287815441758 4.420919468145325 0.9289987404210747 1.1581998241928997 0.6801654711219746 0.06121685742386945 0.12024253238955807 3.722771948474082 0.01647098157214871 0.0360408384776667 4.024502342919781e-06 5.395287815441758 0.22920108377182502 GAGGALLT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GAGGALLTPK 10 0 Q8N1G0;Q8N1G0-2;H0Y5I5 Q8N1G0 ZNF687 Zinc finger protein 687 1 GAGGALLT(1)PK;GAGGALLT(1)PK 89.679 0.015373 0.0 53444.0 64077.0 61070.0 74837.0 73760.0 69477.0 73115.0 68315.0 71175.0 61735.0 True False 62491.01363288468 70438.14108985987 62526.14040926474 70644.1255148275 59307.25749059029 65833.50381273156 66189.01789324029 66521.80363572577 72215.79972512904 72927.06680600879 0.8568973958477617 0.9658710294386357 0.8573790657944429 0.9686955558317725 0.8132406812459883 0.9027307239416799 0.9076056503041293 0.9121689181971149 0.9902468711271252 1.0 16.154166748276964 -8.243729116941314 2.755508073529674 1.0020249220906658 0.8973500355596234 0.43095536092000375 0.04498405982545055 0.24972497631116616 3.492369157014698 0.0383055602754371 0.011143105623337948 5.705200125110726e-09 8.243729116941314 -0.1046748865310424 GAGGALLT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 GAGGALLTPK 10 0 Q8N1G0;Q8N1G0-2;H0Y5I5 Q8N1G0 ZNF687 Zinc finger protein 687 1 GAGGALLT(1)PK;GAGGALLT(1)PK 82.831 0.035151 2756800.0 96447.0 82483.0 81034.0 81128.0 85523.0 90418.0 88149.0 82042.0 83040.0 65952.0 True False 95071.64809378635 82292.01568124037 74371.69732028576 87094.42375507434 80492.70528468738 86551.03291465252 92712.92390363046 85853.97082904597 73687.16075003381 77351.71532448412 1.2290826091569989 1.0638680129591451 0.9614744418828022 1.1259533597893772 1.0406065973718497 1.1189284239086104 1.1985891135666136 1.1099168320818174 0.9526247794366577 1.0 16.239145664277252 -8.25703907649207 24.646811135222244 0.9763123829581931 1.1018226073974384 0.3378338081375213 0.07246174884796687 347.54191350991283 1946672.4652014684 0.054923136901766784 0.0191474726521421 5.533003227015164e-09 8.25703907649207 0.1255102244392453 GAGGPAS(ph)AQGSVK ddPTM_PC-9_AZD4547_30min_R2 1 GAGGPASAQGSVK 13 0 Q9UHV7 Q9UHV7 MED13 Mediator of RNA polymerase II transcription subunit 13 1 GAGGPAS(0.992)AQGS(0.008)VK 69.314 0.0308 4479700.0 12420.0 10354.0 14620.0 21488.0 15985.0 12286.0 11859.0 11016.0 12712.0 14021.0 True False 16369.301647951546 13700.728016494433 14426.129247461708 16534.273586290594 13765.758671184662 11517.754477792543 12914.42802607289 9313.73032249689 13383.930367937654 13530.12905766025 1.2098407619167435 1.0126088197760093 1.0662225900420497 1.2220336935315121 1.0174151785633565 0.8512671555983145 0.9544940754841675 0.6883696587671354 0.9891945827641737 1.0 13.723887980132076 -6.576572697893647 4.277792289101881 0.8820594897706386 1.116235464755242 0.5316936355767862 0.101407598846829 0.16047965020433488 6.155293330601056 0.033022018828018904 0.033564927423424776 2.65110727883527e-07 6.576572697893647 0.2341759749846033 GAGGPAS(ph)AQGSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GAGGPASAQGSVK 13 0 Q9UHV7 Q9UHV7 MED13 Mediator of RNA polymerase II transcription subunit 13 1 GAGGPAS(0.998)AQGS(0.002)VK 106.58 0.001103 3808600.0 11795.0 12351.0 10816.0 13589.0 14654.0 11894.0 15024.0 12554.0 10061.0 11075.0 True False 13791.660538131018 13577.125655084632 11073.894459908415 12827.652386132415 11782.65389461919 11270.257701809658 13600.817955659448 12224.470802062502 10208.123091458001 13082.80983034824 1.0541818399086147 1.037783613088201 0.846446184230261 0.9804967398040185 0.9006210475739643 0.8614554402270681 1.0395945620266973 0.9343918439986305 0.7802699285422755 1.0 13.675384805168541 -5.158725583635522 7.225019602918437 0.9196499620729938 1.049050332272562 0.3298993368825084 0.07305782793886628 0.2951549514979911 18.104612364852382 0.018214720869451608 0.04905115829521238 6.938640973775741e-06 5.158725583635522 0.12940037019956818 GAGGPAS(ph)AQGSVK ddPTM_PC-9_Lapatinib_30min_R1 2 GAGGPASAQGSVK 13 0 Q9UHV7 Q9UHV7 MED13 Mediator of RNA polymerase II transcription subunit 13 1 GAGGPAS(0.994)AQGS(0.006)VK;GAGGPAS(1)AQGSVK 106.29 0.0011345 10356600.0 36264.0 35804.0 37789.0 32682.0 36512.0 33014.0 34670.0 32515.0 35231.0 31351.0 True False 35746.868709996896 35721.09803779123 34682.13428975838 35085.543303956 34364.4359453539 31602.068179392852 36465.04295838713 34025.765601843326 31262.913781122894 36769.97857741838 0.972175402134996 0.9714745403667083 0.9432187787854136 0.954189930518566 0.9345786229654809 0.859452994046635 0.9917069405305958 0.9253681105688661 0.8502293172485679 1.0 15.166240715561388 -5.75861279520723 1.2658159809926843 0.9237739566598455 0.9719645204801296 0.119009782690228 0.04530752290311344 1.0179130390029225 3.2217408384103767 0.015617150284431041 0.04006959457088932 1.743360512088516e-06 5.75861279520723 0.04819056382028408 GAGGS(ph)PVGVEEGLVNVGTGQK ddPTM_PC-9_AZD4547_30min_R2 2 GAGGSPVGVEEGLVNVGTGQK 21 0 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 GAGGS(1)PVGVEEGLVNVGTGQK;GAGGS(1)PVGVEEGLVNVGTGQK 248.46 1.8616999999999996e-61 95099000.0 60224.0 68700.0 81793.0 95412.0 91742.0 83729.0 76947.0 105036.0 75408.0 84094.0 True False 79373.97926298187 90905.93149827766 80708.37137740312 73416.23750070547 79005.20688219093 78493.41239387023 83795.1339339094 88805.09968716248 79393.9129315168 81149.89465622163 0.9781156167760521 1.1202224215248324 0.9945591638696643 0.9046991103527793 0.9735712808609757 0.9672645014068698 1.032596952699617 1.0943341339304369 0.9783612568797068 1.0 16.308301601506365 -7.304914438555867 13.785508171226075 1.0341919403035011 0.9912900060098552 0.08182692030012062 0.05753499635110063 7.80905272866309 2472.5143956694646 0.025790197973836478 0.01739545035619817 4.9554781030419265e-08 7.304914438555867 -0.04290193429364597 GAGGS(ph)PVGVEEGLVNVGTGQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 GAGGSPVGVEEGLVNVGTGQK 21 0 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 GAGGS(1)PVGVEEGLVNVGTGQK;GAGGS(1)PVGVEEGLVNVGTGQK;GAGGS(1)PVGVEEGLVNVGTGQK;GAGGS(1)PVGVEEGLVNVGTGQK;GAGGS(1)PVGVEEGLVNVGTGQK;GAGGS(1)PVGVEEGLVNVGTGQK 266.28 1.1309999999999997e-86 73973300.0 178054.0 171632.0 189319.0 205198.0 223278.0 186612.0 200378.0 155293.0 167268.0 162108.0 True False 208195.02547319917 188670.4906836278 193833.08295630594 193701.4213208919 179528.27871453404 176825.73820834912 181396.74522890887 151216.7232965346 169713.97806003367 191496.89715377815 1.0871979053843985 0.9852404581371329 1.0121996013368915 1.0115120620745277 0.9374996743177885 0.9233869625905865 0.9472568377086625 0.7896562583732243 0.8862492321415939 1.0 17.546961490622955 -6.403278298452669 0.9608005374896317 0.8876013977396174 1.0358199270284876 0.48790269174504597 0.05553279363364781 0.4468814073785041 0.8880712279576969 0.027518278742454924 0.03705694729505245 3.9511334797556015e-07 6.403278298452669 0.14821852928887014 GAGGS(ph)PVGVEEGLVNVGTGQK ddPTM_PC-9_Lapatinib_30min_R1 4 GAGGSPVGVEEGLVNVGTGQK 21 0 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 GAGGS(1)PVGVEEGLVNVGTGQK;GAGGS(1)PVGVEEGLVNVGTGQK;GAGGS(1)PVGVEEGLVNVGTGQK;GAGGS(1)PVGVEEGLVNVGTGQK 230.62 4.257899999999999e-79 90879300.0 126064.1 140187.9 151094.1 124993.9 145473.9 150690.2 140001.1 135228.1 149561.3 111130.1 True False 124266.40281667566 139863.30353066907 138671.7263380926 134186.36837342707 136917.41121469156 144245.5314220133 147249.67192735677 141511.29120044995 132716.1314436903 130338.78971344979 0.9534107466386308 1.0730750518564653 1.0639328985865435 1.0295198280453286 1.0504732437343087 1.1066968761881057 1.1297455826549072 1.085718929196465 1.0182397100315808 1.0 16.991906978136484 -6.535970954022759 20.749656072949207 1.0774355267462021 1.036051015900891 0.10638138904542349 0.047097598598144795 61.39883195300419 97304.90358179327 0.015550435132848671 0.015571505686644551 2.91091179576563e-07 6.535970954022759 -0.04138451084531103 GAGIGGLGITVEGPSESK ddPTM_PC-9_Lapatinib_30min_R1 2 GAGIGGLGITVEGPSESK 18 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 160.56 2.6047e-05 9633100.0 46070.0 44859.0 49232.0 42941.0 45924.0 39278.0 49757.0 33560.0 43583.0 39918.0 False True 45413.033351796716 44755.13174162875 45184.33500101575 46099.02438697673 43222.840610057894 37598.17150149002 52333.17399712922 35119.3201168034 38674.22359066389 46817.77311260839 0.9699955878415463 0.9559431977676838 0.9651107260555983 0.9846479514541862 0.923214363615634 0.8030747513568632 1.1178057074875158 0.7501279488952347 0.8260585888534844 1.0 15.514768693841285 -6.5162570786163165 24.204324842164894 0.8936346629770318 0.9660005525563893 0.09984792494214967 0.097669683352333 478.09585724025527 1747604.2294915877 0.031360870449086024 0.0325309591729179 3.0460913361255655e-07 6.5162570786163165 0.07236588957935752 GAGNCPECGT(ph)PLRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GAGNCPECGTPLRK 14 1 P51948;P51948-2 P51948 MNAT1 CDK-activating kinase assembly factor MAT1 1 GAGNCPECGT(1)PLRK 67.994 0.028045999999999998 8329400.0 26963.0 26560.0 18518.0 26144.0 29102.0 26025.0 26145.0 25597.0 20173.0 19119.0 True False 31527.303356475353 29196.701271075057 18959.539349906074 24679.236439991608 23399.672010454993 24660.20318560589 23668.356326591867 24925.105872263328 20467.99196143349 22585.123354079285 1.3959323073956533 1.2927403943446516 0.8394702589251802 1.0927209053978484 1.0360657165163805 1.0918781712632004 1.0479622340569121 1.1036072498475595 0.9062599145705617 1.0 14.463085172972098 -5.088355136735222 5.9342663923047745 1.0265256692161584 1.3724475636137363 0.7279267481022389 0.08136463557138365 0.09948539362509819 5.24826033068608 0.020057237895319553 0.05596699299066456 8.159148983161487e-06 5.088355136735222 0.3459218943975779 GAGPQLLEELDNAPGS(ph)DAAELELAPARTPPDSVKDASAAEPAAAER ddPTM_PC-9_AZD4547_30min_R2 1 GAGPQLLEELDNAPGSDAAELELAPARTPPDSVKDASAAEPAAAER 46 2 Q9UHR6 Q9UHR6 ZNHIT2 Zinc finger HIT domain-containing protein 2 1 GAGPQLLEELDNAPGS(0.706)DAAELELAPART(0.215)PPDS(0.071)VKDAS(0.007)AAEPAAAER 42.18 0.0033905000000000003 4437800.0 8409.6 6302.1 11329.0 18793.0 13453.0 12050.0 7173.0 12208.0 10637.0 11608.0 True False 11083.677869453573 8339.130580717561 11178.770057762893 14460.564198955639 11585.28316568328 11296.51159510012 7811.383104057745 10321.534111931926 11199.250104134102 11201.607453200217 0.9894720838737344 0.7444583838130422 0.9979612394441836 1.2909365249024471 1.0342518441291613 1.008472368121844 0.6973448352563087 0.9214332991987806 0.9997895526087694 1.0 13.45141815632851 -7.059035249793964 24.99919149969324 0.8916394896206312 1.012367053224963 0.11056974360161864 0.14582975592092065 596.6347484178569 252650.08532284037 0.0604395325336478 0.04681635901390666 8.729005159748968e-08 7.059035249793964 0.12072756360433168 GAGPQLLEELDNAPGS(ph)DAAELELAPARTPPDSVKDASAAEPAAAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GAGPQLLEELDNAPGSDAAELELAPARTPPDSVKDASAAEPAAAER 46 2 Q9UHR6 Q9UHR6 ZNHIT2 Zinc finger HIT domain-containing protein 2 1 GAGPQLLEELDNAPGS(0.525)DAAELELAPART(0.429)PPDS(0.041)VKDAS(0.005)AAEPAAAER;GAGPQLLEELDNAPGS(0.532)DAAELELAPART(0.466)PPDS(0.002)VKDAS(0.001)AAEPAAAER 69.01899999999999 8.955199999999999e-10 5949800.0 11316.7 9689.599999999999 9051.4 9534.8 12481.5 13756.7 13665.9 13949.599999999999 13018.599999999999 9634.3 True False 13232.393794986641 10651.519451664488 9267.219703625653 9000.59606823868 10035.839674197448 13035.274434713712 12371.367019451973 13583.437780822933 13208.972396228515 11380.922324923164 1.1626820232318893 0.9359100385334015 0.8142766850566497 0.7908494418355013 0.8818125093622589 1.1453618663372889 1.087026751106088 1.1935269737388916 1.160624070625813 1.0 13.474329859836574 -6.762340733823401 24.999461402546153 1.1275108214384482 0.9054237726889232 0.46747463011267165 0.10619559754468096 21.36362548762181 592517.7378233627 0.03831689842203223 0.035758241883398593 1.728459731830302e-07 6.762340733823401 -0.222087048749525 GAGPQLLEELDNAPGSDAAELELAPART(ph)PPDSVKDASAAEPAAAER ddPTM_PC-9_AZD4547_30min_R2 1 GAGPQLLEELDNAPGSDAAELELAPARTPPDSVKDASAAEPAAAER 46 2 Q9UHR6 Q9UHR6 ZNHIT2 Zinc finger HIT domain-containing protein 2 1 GAGPQLLEELDNAPGS(0.212)DAAELELAPART(0.582)PPDS(0.18)VKDAS(0.026)AAEPAAAER 53.419 4.1413999999999993e-05 5079300.0 12766.0 10561.0 14625.0 22727.0 22554.0 15640.0 13203.0 16343.0 13058.0 15035.0 True False 16825.32245070446 13974.636718388807 14431.062944194759 17487.641278649757 19422.7664103784 14662.028327582233 14378.041422399881 13817.564874779117 13748.219221564654 14508.629226297837 1.159676919733221 0.9631948339446752 0.9946537828699569 1.205326913100258 1.3387044432270259 1.0105729561967405 0.9909993010462176 0.9523687358233595 0.9475891214205895 1.0 13.82462359972313 -6.980516489926493 24.999794659431664 0.973343670922244 1.1248561921945128 0.3728173686018029 0.09931348472521585 306.64313181316106 393460.4898717919 0.03912658192600327 0.03450218984695052 1.0458839780604966e-07 6.980516489926493 0.15151252127226877 GAGPQLLEELDNAPGSDAAELELAPART(ph)PPDSVKDASAAEPAAAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GAGPQLLEELDNAPGSDAAELELAPARTPPDSVKDASAAEPAAAER 46 2 Q9UHR6 Q9UHR6 ZNHIT2 Zinc finger HIT domain-containing protein 2 1 GAGPQLLEELDNAPGS(0.191)DAAELELAPART(0.726)PPDS(0.081)VKDAS(0.002)AAEPAAAER 64.725 2.4591999999999995e-09 2617000.0 14494.0 5478.6 11614.0 19519.0 18313.0 18673.0 18733.0 16581.0 15633.0 11688.0 True False 16947.547930451125 6022.479201193965 11890.921806340273 18425.41371145182 14724.699110970454 17693.75500806221 16958.47462482484 16145.766319021695 15861.603050269663 13806.941877842903 1.2274657256034518 0.43619211658004564 0.8612277730684578 1.3345036051046573 1.0664707102591884 1.281511515338294 1.2282571169535705 1.1693948205092461 1.1488136323456275 1.0 13.753106189642295 -5.651577580371681 6.256693337834248 1.183700378898799 0.7892867473540357 0.36399328157746236 0.2002586369900059 0.18428899516574979 9.437985898758331 0.0509145992578779 0.08885404285215882 2.230603707088042e-06 5.651577580371681 -0.3944136315447633 GAGQQQS(ph)QEMMEVDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GAGQQQSQEMMEVDR 15 0 Q15435;B5MBZ8;Q15435-3;C9JRC4 Q15435 PPP1R7 Protein phosphatase 1 regulatory subunit 7 1 GAGQQQS(1)QEMMEVDR 76.943 0.008026899999999998 4321100.0 13666.0 14739.0 19003.0 20203.0 20248.0 18365.0 18298.0 15772.0 15908.0 14416.0 True False 15979.383884196568 16202.19051334245 19456.103589278817 19071.091409009736 16280.549751484192 17401.907070265206 16564.68097395211 15358.001711815337 16140.62440502076 17029.50668300678 0.9383351016352048 0.9514186649640366 1.142493670042331 1.1198851360762077 0.9560200453563373 1.0218679492125295 0.9727046873578253 0.9018465418696252 0.9478034041424694 1.0 14.055749022652336 -7.187205658103783 1.6683647280989973 0.9434642314511964 1.030900330925239 0.1821732538006684 0.06775225019892969 0.6300825030743267 3.4442335437413125 0.03909291709026015 0.02537091576352683 6.498218973769307e-08 7.187205658103783 0.08743609947404252 GAGQQQS(ph)QEMMEVDR ddPTM_PC-9_Lapatinib_30min_R1 3 GAGQQQSQEMMEVDR 15 0 Q15435;B5MBZ8;Q15435-3;C9JRC4 Q15435 PPP1R7 Protein phosphatase 1 regulatory subunit 7 1 GAGQQQS(1)QEMMEVDR;GAGQQQS(1)QEMMEVDR;GAGQQQS(1)QEMMEVDR 191.96 1.492e-38 0.0 22221.199999999997 24558.5 29086.2 20167.9 24755.9 28307.1 16852.4 26197.1 27859.8 21550.6 True False 21904.32161313099 24501.63630211974 26694.844911978886 21651.11464414217 23299.80663397202 27096.471320073033 17724.934812573512 27414.312903215447 24721.935947300037 25275.59249563052 0.8666195111714063 0.9693793056030406 1.0561511037414342 0.8566016661285022 0.9218302850071641 1.072040994677268 0.7012668373901694 1.084616034538247 0.9780952098976039 1.0 14.625457290886011 GAGSIAGASAS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 GAGSIAGASASPK 13 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 GAGSIAGASAS(1)PK;GAGSIAGAS(0.034)AS(0.966)PK;GAGSIAGASAS(1)PK 168.89 0.00021005 59808600.0 111285.0 120768.0 112364.0 132177.0 124661.0 141436.0 141775.0 140024.0 123900.0 128734.0 True False 146671.31512820337 159803.89425304244 110873.97994266657 101705.63476429321 107353.9719554927 132591.98456137575 154392.70034543256 118386.50823141864 130449.10105313672 124227.06184357981 1.1806712076381891 1.2863855256776426 0.8925106840430088 0.8187075606147363 0.864175408822493 1.0673357527229341 1.242826627742639 0.9529848526924408 1.0500860208493974 1.0 16.92261996147937 -5.255657523446284 24.98644023829153 0.9861396749058571 1.233528385006733 0.42030262567600296 0.1162430397121182 492.700163136948 2129200.09854082 0.03344217879731643 0.08359059190769522 5.55063252978441e-06 5.255657523446284 0.24738871010087582 GAGSIAGASAS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GAGSIAGASASPK 13 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 GAGSIAGAS(0.052)AS(0.948)PK;GAGSIAGAS(0.022)AS(0.978)PK;GAGSIAGAS(0.013)AS(0.987)PK 145.61 9.886299999999999e-05 27718200.0 131601.0 141830.0 92618.0 124392.0 134546.0 91416.0 142960.0 119090.0 98170.0 80798.0 True False 153878.45006177045 155909.94507818422 94826.36437572076 117422.71952430508 108182.67714654258 86621.98403132947 129417.7938592302 115964.01368628503 99605.55053060669 95446.03780338398 1.6122036451503152 1.6334878709093623 0.9935076044860057 1.230252425629154 1.133443353294515 0.9075492919859932 1.3559263101714818 1.2149693832777793 1.0435797317830122 1.0 16.542397688650063 -5.252896416229586 24.98951124037621 1.124279465774748 1.6228458379151922 0.7244945257878821 0.12627619922380648 318.5647783084964 931847.0118249079 0.03212343134875126 0.08213694043640797 5.586034115980246e-06 5.252896416229586 0.4985663721404443 GAGSIAGASAS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 GAGSIAGASASPK 13 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 GAGSIAGAS(0.003)AS(0.997)PK;GAGSIAGAS(0.01)AS(0.99)PK;GAGSIAGASAS(1)PK 156.52 4.7578e-12 34067000.0 135381.0 114515.0 99816.0 101142.0 105297.0 90672.0 102134.0 93249.0 95261.0 90735.0 True False 133450.44211416543 114249.8475532809 91609.51378090239 108580.32007982138 99103.6374818672 86794.1699267556 107421.99877449991 97581.68896221113 84531.70303719866 106418.42385321234 1.2540163374176594 1.0735908634661868 0.8608426103666359 1.0203150558740752 0.9312639098899383 0.8155934544423873 1.0094304621789159 0.9169623588563001 0.7943333492121345 1.0 16.69938841569583 -4.928870996669937 2.628896760473127 0.9192409228341408 1.2745035666650002 0.6644104724399951 0.07491947291849169 0.20478652905578026 2.348347081061174 0.019261083668941588 0.14056799217747046 1.1779558229045053e-05 4.928870996669937 0.35526264383085937 GAGTDDHTLIR ddPTM_PC-9_AZD4547_30min_R2 2 GAGTDDHTLIR 11 0 D6RBE9;P08758;D6RBL5 D6RBE9 ANXA5 Annexin;Annexin A5 0 ; 108.47 0.0018307000000000002 18296500.0 109536.0 105307.0 149900.0 207073.0 166880.0 153889.0 118308.0 162834.0 125517.0 135307.0 False True 144366.16950966374 139345.42835937615 147912.22805707998 159335.51909595807 143711.59255847993 144266.29650276888 128837.18280703553 137671.74685307383 132151.57237196574 130569.94311424522 1.1056615792759226 1.0672090761152635 1.1328198858726677 1.2203077928627397 1.1006483508439313 1.1048966788362595 0.9867292558617906 1.0543908005888822 1.0121132721666015 1.0 16.994463304623913 -7.128184415559701 4.220308885157991 1.01813436787071 1.125945319296562 0.6361221182905503 0.04032365189884106 0.17176774732844854 5.067724815517918 0.01717032623269439 0.013159345315837467 7.444158036250065e-08 7.128184415559701 0.10781095142585206 GAGTDDHTLIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GAGTDDHTLIR 11 0 D6RBE9;P08758;D6RBL5 D6RBE9 ANXA5 Annexin;Annexin A5 0 ; 195.83 0.00010354 7457000.0 78794.0 89574.0 105752.0 98716.0 100831.0 80378.0 103004.0 91169.0 81202.0 73636.0 False True 92132.2679475622 98466.31474605724 108273.52874669358 93185.26256159019 81073.88937138989 76162.83618261787 93246.71543561934 88775.91035154006 82389.42563090865 86985.62389774459 1.0591666049997839 1.1319837731095508 1.244729001127518 1.071271991692944 0.9320377981848563 0.8755795816576613 1.0719784633060163 1.020581406140169 0.947161403679314 1.0 16.408489366198026 -6.023845773811167 6.003579452658519 0.9771324061746897 1.1466478540719771 0.5854789682322945 0.06496712145601224 0.1279696538853765 16.017200333613395 0.020126055809037736 0.02740833470456021 9.465732477595644e-07 6.023845773811167 0.16951544789728745 GAGTDDHTLIR ddPTM_PC-9_Lapatinib_30min_R1 2 GAGTDDHTLIR 11 0 D6RBE9;P08758;D6RBL5 D6RBE9 ANXA5 Annexin;Annexin A5 0 ; 121.61 0.00063038 16946100.0 64120.0 72880.0 89464.0 75516.0 90364.0 78320.0 76879.0 66616.0 79782.0 77041.0 False True 63205.63704183213 72711.25083773377 82108.61526102683 81069.69855399118 85048.96718245941 74970.43617283725 80859.41844816404 69711.22255366434 70796.1110182948 90357.4341993203 0.6995067711020461 0.8047069007884768 0.9087090175657565 0.8972111622288741 0.9412503568311724 0.8297096618243859 0.8948839590751936 0.7715051137893946 0.7835117458307306 1.0 16.463355683918422 -13.487035456861348 0.014748383962258402 1.919433190415063 4.364059679638471e-06 0.21928403865094204 0.07606720934983094 11103.740973824239 14.690593642869006 1151.8280969814432 790.5979848883878 3.258100999844733e-14 13.487035456861348 -1.9194288263553834 GAGTDEGCLIEILASR ddPTM_PC-9_Lapatinib_30min_R1 4 GAGTDEGCLIEILASR 16 0 P09525-2;P09525 P09525-2 ANXA4 Annexin A4 0 ;;; 187.74 2.1394000000000002e-07 35128100.0 17200.5 16559.7 20470.8 18648.0 18390.0 19076.7 16135.3 16504.2 18456.399999999998 15923.5 False True 16955.217715814626 16521.357032074946 18787.769843573158 20019.4361279044 17308.336356131083 18260.834010959705 16970.706883370745 17271.045383544308 16377.645877491881 18675.855758269954 0.9078683159301333 0.8846372153393312 1.0059924475082567 1.0719421046631015 0.9267760781706984 0.9777776315751169 0.9086976844879441 0.9247793304409317 0.8769421915373067 1.0 14.188886730726006 -7.262128037091875 24.99914288783656 0.9213364116165135 0.9642876924622881 0.0773018937523342 0.057249979876488465 159.20895546958016 5779315.589947576 0.02436345703388022 0.017529078326174733 5.4685471744230316e-08 7.262128037091875 0.0429512808457746 GAGTGGLGLAVEGPSEAK ddPTM_PC-9_Lapatinib_30min_R1 2 GAGTGGLGLAVEGPSEAK 18 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 251.68 1.2204999999999998e-53 20204600.0 55043.0 60421.0 62671.0 56765.0 56867.0 51141.0 65207.0 51639.0 57010.0 54870.0 False True 54258.07672635004 60281.098886755164 57518.43229705592 60939.68746248891 53522.19486482366 48953.81864549372 68583.09939969865 54038.33645743777 50588.93345808563 64354.20639032076 0.8431162432066097 0.9367079833311687 0.8937789077561684 0.9469417910754406 0.8316813751101388 0.7606933779678565 1.0657127676119387 0.8397016992127098 0.7861014267078973 1.0 15.973746830095228 -10.40805913048289 4.909117267124352 1.0000002785572923 0.8820154301585348 0.15715841485215487 0.0841697398089803 116504617.7972077 18.647804800212583 523.1669218589236 0.02022735261502742 3.907876852667183e-11 10.40805913048289 -0.11798484839875756 GAGTGGLGLTVEGPCEAK ddPTM_PC-9_Lapatinib_30min_R1 2 GAGTGGLGLTVEGPCEAK 18 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4;Q14315-2;Q14315 O75369-2;Q14315-2 FLNB;FLNC Filamin-B;Filamin-C 0 ; 201.95 3.3441e-54 3756600.0 32314.0 33152.0 38313.0 28091.0 33525.0 27584.0 30413.0 28294.0 34825.0 31850.0 False True 31853.19643433814 33075.23858085283 35163.05303245688 30156.905848828963 31553.125412685986 26404.296621444613 31987.63632804811 29608.642532325248 30902.641776492404 37355.23006254267 0.852710487420566 0.8854245717527641 0.9413153920772139 0.8073007661400616 0.844677582224968 0.7068433677757235 0.8563094451430825 0.7926237499475292 0.8272641267301284 1.0 15.189022626769018 -5.780231149134465 24.975198653603897 0.8210629580903471 0.8923776061465778 0.109071405245593 0.07205409561350323 391.57695070439416 520423.86873329506 0.01917429356002717 0.028494599229113116 1.658703843009247e-06 5.780231149134465 0.07131464805623067 GAGTNEDALIEILTTR ddPTM_PC-9_Lapatinib_30min_R1 2 GAGTNEDALIEILTTR 16 0 P12429;D6RFG5;D6RA82;D6RCA8 P12429 ANXA3 Annexin A3;Annexin 0 ; 227.74 3.8449999999999997e-28 4841500.0 12363.4 11188.2 14260.900000000001 12423.4 12193.8 14649.5 10223.8 11294.3 12420.7 11906.7 False True 12187.095648830122 11162.294410300967 13088.423850665942 13337.058279247505 11476.58465793319 14022.975034652423 10753.138338562398 11819.074409869268 11021.74997023056 13964.757230319523 0.8727037246569644 0.7993189015893523 0.9372467873805258 0.9550512092176445 0.8218248601569565 1.0041689091598744 0.7700197118511855 0.8463501523827665 0.789254677933157 1.0 13.76950287291966 -10.401574545805003 10.051962660982985 0.9999974530905834 0.8682881569036349 0.22912406006463126 0.07352961736580846 0.0 0.0 0.07075607932987243 0.017160869925390974 3.966664360638598e-11 10.401574545805003 -0.1317092961869485 GAIILAK ddPTM_PC-9_Lapatinib_30min_R1 2 GAIILAK 7 0 H0YEN5;P15880;E9PMM9;I3L404;E9PPT0;E9PM36 H0YEN5 RPS2 40S ribosomal protein S2 0 ; 143.22 0.0090842 10024000.0 112536.0 108239.0 103068.0 94691.0 107310.0 110506.0 118113.0 96985.0 108864.0 103880.0 False True 110931.21600342532 107988.37924568422 94594.14689398567 101654.89201991595 100998.23677957729 105779.91598206777 124228.31320865259 101491.27716114926 96602.58993125826 121835.51958860054 0.9104997982362159 0.8863456208035746 0.7764086139526449 0.8343617063658604 0.8289720199874054 0.8682190246264194 1.0196395404897665 0.8330187904467659 0.7928934867061282 1.0 16.89457526830376 -7.007759998891803 24.86395124521575 0.9041094818944236 0.8452035043618574 0.14905678199742134 0.07143884955139276 764.9840704754175 2451102.4531370346 0.026716289673284606 0.022536429542138286 9.822906294246865e-08 7.007759998891803 -0.05890597753256621 GAILS(ph)EEELAAMSPTAAAVAK ddPTM_PC-9_AZD4547_30min_R2 1 GAILSEEELAAMSPTAAAVAK 21 0 P12270;P12270-2 P12270 TPR Nucleoprotein TPR 1 GAILS(0.929)EEELAAMS(0.057)PT(0.014)AAAVAK 76.32600000000001 0.0011827 8839900.0 30884.0 21761.0 39886.0 51112.0 45706.0 24849.0 34783.0 37011.0 28163.0 36270.0 True False 40704.469572893344 28794.817690451557 39357.08557895056 39328.91807252814 39360.510842988166 23295.188101796102 37878.61961640046 31291.80037817106 29651.63868409596 35000.198339728784 1.1629782545171932 0.8227044147280306 1.1244817871296535 1.1236770057924448 1.124579651261861 0.6655730312063316 1.0822401418624068 0.8940463729501694 0.847184875819356 1.0 15.095075477119407 GAILSEEELAAMS(ph)PTAAAVAK ddPTM_PC-9_AZD4547_30min_R2 3 GAILSEEELAAMSPTAAAVAK 21 0 P12270;P12270-2 P12270 TPR Nucleoprotein TPR 1 GAILSEEELAAMS(0.999)PT(0.001)AAAVAK;GAILSEEELAAMS(0.849)PT(0.151)AAAVAK;GAILSEEELAAMS(0.966)PT(0.034)AAAVAK 176.46 1.2481e-12 24270600.0 83494.4 78975.0 105577.0 139840.0 110466.0 110362.0 91389.0 125625.0 94073.0 98068.0 True False 110043.88240859316 104502.1243097013 104176.97999721377 107602.04850646282 95129.70268195719 103461.04669364632 99522.44395604795 106212.54282531513 99045.506726164 94634.66916957626 1.162828415571518 1.1042689241343837 1.1008331398141056 1.1370256741073428 1.0052309953289305 1.0932679070104216 1.0516488812119507 1.1223428343685804 1.0466091084302724 1.0 16.530081187597133 -1.5228787452803376 0.0940217763736673 0.9666844160105199 1.44642650136573 0.47360226320282617 0.037668846066336525 142.00598466066964 0.958248321554335 0.6050111147041394 8.779641076769481 0.029999999999999995 1.5228787452803376 0.4797420853552101 GAILSEEELAAMS(ph)PTAAAVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GAILSEEELAAMSPTAAAVAK 21 0 P12270;P12270-2 P12270 TPR Nucleoprotein TPR 1 GAILSEEELAAMS(0.985)PT(0.015)AAAVAK;GAILS(0.001)EEELAAMS(0.902)PT(0.097)AAAVAK;GAILSEEELAAMS(0.826)PT(0.174)AAAVAK;GAILS(0.001)EEELAAMS(0.771)PT(0.228)AAAVAK 184.01 5.2933999999999996e-15 35157700.0 104171.0 108256.0 111949.0 129144.0 134918.0 136803.0 131102.0 124651.0 112856.0 99347.0 True False 121805.09282896569 119002.94024102057 114618.28872894701 121908.48037049737 108481.78641696658 129628.8098520822 118683.06946371602 121379.0433286518 114506.3054974243 117357.82466958054 1.03789494370662 1.0140179453400047 0.9766565548709968 1.0387759036411006 0.9243677336589671 1.1045604348670441 1.0112923428656477 1.0342645977836837 0.975702351503322 1.0 16.840554509188102 -6.758467182613502 24.999987874887395 1.0264384966547697 1.0002550010350855 0.08501162723976019 0.043672254729041286 218.38381774120046 1836899.370947432 0.014210612777146069 0.013646451340225374 1.7439451333956767e-07 6.758467182613502 -0.02618349561968425 GAILSEEELAAMS(ph)PTAAAVAK ddPTM_PC-9_Lapatinib_30min_R1 9 GAILSEEELAAMSPTAAAVAK 21 0 P12270;P12270-2 P12270 TPR Nucleoprotein TPR 1 GAILSEEELAAMS(0.913)PT(0.087)AAAVAK;GAILSEEELAAMS(0.982)PT(0.018)AAAVAK;GAILSEEELAAMS(0.959)PT(0.041)AAAVAK;GAILSEEELAAMS(0.71)PT(0.29)AAAVAK;GAILSEEELAAMS(0.706)PT(0.294)AAAVAK;GAILS(0.003)EEELAAMS(0.973)PT(0.024)AAAVAK;GAILSEEELAAMS(0.848)PT(0.152)AAAVAK;GAILSEEELAAMS(0.949)PT(0.051)AAAVAK;GAILSEEELAAMS(0.994)PT(0.006)AAAVAK 170.61 7.5821e-09 41220600.0 295412.6 267535.7 310503.9 262866.2 283927.1 292100.1 274342.1 249365.2 283759.8 238042.6 True False 291199.9621519633 266916.237523995 284975.4679217149 282198.2572439367 267227.0662001561 279607.6596415906 288546.19157179503 260951.6175444189 251799.7832008367 279187.94623817335 1.0430248371236723 0.9560449909119305 1.0207298408169967 1.010782381712122 0.9571583222012977 1.0015033364050008 1.033519517800522 0.934680816491278 0.9019006249862521 1.0 18.090877129889087 -7.779068064396994 24.988365547818702 0.9387180000032939 1.0005580209705647 0.35452460864600244 0.03520578437526078 250.8479976086408 355567.6544108353 0.018343691460082037 0.008842086479045438 1.6631519740040274e-08 7.779068064396994 0.061840020967270815 GAILSEEELAAMSPT(ph)AAAVAK ddPTM_PC-9_AZD4547_30min_R2 1 GAILSEEELAAMSPTAAAVAK 21 0 P12270;P12270-2 P12270 TPR Nucleoprotein TPR 1 GAILSEEELAAMS(0.222)PT(0.778)AAAVAK 180.18 2.4171e-12 10605000.0 32703.0 35211.0 41267.0 50782.0 45650.0 46894.0 39839.0 42198.0 42727.0 42950.0 True False 43101.87373534296 46592.26716136618 40719.772616621216 39074.99447407894 39312.285476357836 43961.71076685684 43384.5938216306 35677.26871357332 44985.46199110068 41446.33357296255 1.0399441885363874 1.1241589579774212 0.9824698376501196 0.94278531067871 0.9485105698710862 1.0606899809235526 1.0467655418845656 0.8608063883568059 1.085390627180757 1.0 15.338956863174953 -5.276472787522709 24.066092417968925 0.9872075842630458 1.0820515704941562 0.23980033626337227 0.06462734805006201 568.8248459578584 910599.3467440632 0.01658311364951092 0.03477312370631457 5.290871482661599e-06 5.276472787522709 0.09484398623111046 GAKEEHGGLIR ddPTM_PC-9_AZD4547_30min_R2 1 GAKEEHGGLIR 11 1 P26368;P26368-2 P26368 U2AF2 Splicing factor U2AF 65 kDa subunit 0 52.167 0.045614999999999996 2091000.0 22177.0 16959.0 26049.0 40374.0 32638.0 28604.0 21033.0 26267.0 25264.0 26849.0 False True 29228.824689744062 22440.665098679656 25703.57323988576 31066.398072081927 28106.77707288863 26815.387358194497 22904.896253679977 22208.038705612387 26599.403462521776 25909.02468219957 1.1281329593940799 0.8661331475783879 0.9920702749395672 1.199057025617242 1.0848257476939684 1.034982508493175 0.8840508870801479 0.857154562088557 1.026646266649957 1.0 14.66116708736241 -7.172816227297832 6.356634058482143 0.9304063200794938 1.048977010931666 0.240497645878896 0.09405257519527692 0.3578746278373353 21.238084411334214 0.03821914981387719 0.029485252640626073 6.717130296997397e-08 7.172816227297832 0.11857069085217231 GAKEEHGGLIRS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 GAKEEHGGLIRSPR 14 2 P26368;P26368-2 P26368 U2AF2 Splicing factor U2AF 65 kDa subunit 1 GAKEEHGGLIRS(1)PR;GAKEEHGGLIRS(1)PR 63.31 0.01438 395595000.0 326446.0 214553.0 431994.0 743026.0 592507.0 428770.0 309984.0 390796.0 314783.0 449716.0 True False 430249.0375013845 283903.06143740873 426265.47730013466 571732.8353372643 510247.63046528806 401958.9441187609 337571.9754814217 330407.4577987015 331421.78673776885 433971.5797228964 0.9914221520591536 0.6541973592341903 0.9822428408153311 1.3174430355608369 1.1757627787310316 0.926233336236957 0.7778665499177879 0.7613573635620939 0.7636946800741915 1.0 18.727241039836088 -7.031801684450554 5.656860346522164 0.8103029576957641 1.0209518138653657 0.22918422824861584 0.17046580674499093 0.3116578144222981 28.992176077718515 0.07255187246196829 0.057934163173682864 9.293906853984882e-08 7.031801684450554 0.2106488561696016 GAKEEHGGLIRS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 GAKEEHGGLIRSPR 14 2 P26368;P26368-2 P26368 U2AF2 Splicing factor U2AF 65 kDa subunit 1 GAKEEHGGLIRS(1)PR;GAKEEHGGLIRS(1)PR;GAKEEHGGLIRS(1)PR 56.768 0.022269 551526000.0 761100.0 343046.0 492490.0 384350.0 335042.0 354319.0 258889.0 246278.0 441217.0 299488.0 True False 750246.574431353 342251.698063683 451999.3732663757 412616.3811540136 315335.4882779156 339165.6023279301 272293.00566639437 257720.97496204168 391522.49523901416 351254.1017573247 2.135908365704111 0.974370680232337 1.2868159289956254 1.174694840828031 0.8977417963243468 0.9655847451491218 0.7752023515287426 0.7337166275715026 1.1146417743742396 1.0 18.422155546888952 -2.714603912657698 1.236838926658853 0.9549827650160111 199.99999910117097 0.7901984909458726 0.1736858006020375 118.4488843435865 1.3862587822024046 0.05327994163149056 65671.24195906482 0.0019292836656244993 2.714603912657698 199.04501633615496 up GAKLT(ph)PEEEEILNK ddPTM_PC-9_AZD4547_30min_R2 2 GAKLTPEEEEILNK 14 1 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 1 GAKLT(1)PEEEEILNK;GAKLT(1)PEEEEILNK 97.214 0.0019875 28269000.0 81885.0 88430.0 93800.0 105512.0 106101.0 113227.0 97573.0 107765.0 102334.0 100641.0 True False 107922.72668619281 117013.26815709916 92556.15071216886 81187.8385441499 91370.70758657272 106146.89779073875 106256.80797605253 91112.3954433442 107743.1663209984 97117.58922273607 1.1112582957416242 1.2048617464003661 0.9530317983892115 0.8359746076269273 0.9408255324070796 1.0929729479517272 1.094104670703429 0.9381657449752057 1.1094093992993679 1.0 16.56744498916229 -5.262940459354628 24.989806603288958 0.9926963412255781 1.1580600271958805 0.3753753787706853 0.0837820292844784 137.06635328532738 2281905.301036745 0.023500526854854417 0.05351488112186658 5.458326882055839e-06 5.262940459354628 0.16536368597030238 GAKLT(ph)PEEEEILNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GAKLTPEEEEILNK 14 1 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 1 GAKLT(1)PEEEEILNK;GAKLT(1)PEEEEILNK;GAKLT(1)PEEEEILNK 93.427 0.0043381999999999995 10009000.0 68775.8 68785.0 54016.6 81017.0 90992.0 65327.5 94116.0 70531.0 70912.0 56219.9 True False 80418.18455603156 75613.52021577176 55304.560603096295 76477.88015065796 73162.7707915375 61901.61089750888 85200.6511391672 68679.63598377167 71948.95384767612 66412.1228335165 1.210896160594441 1.1385499663265024 0.832747971958901 1.1515650590235542 1.101647826782223 0.9320830031692454 1.2829081123148287 1.0341430608375435 1.083370788011693 1.0 16.01915899394442 GAKLT(ph)PEEEEILNK ddPTM_PC-9_Lapatinib_30min_R1 1 GAKLTPEEEEILNK 14 1 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 1 GAKLT(1)PEEEEILNK 92.096 0.0030855 13287000.0 28664.0 26953.0 30092.0 35416.0 41889.0 41812.0 34116.0 37531.0 36743.0 31288.0 True False 28255.246103666173 26890.59198448737 27617.95191847915 38020.61078431261 39425.17137694264 40023.798228532556 35882.35954912996 39274.827273651594 32604.61641905704 36696.08911136061 0.7699797659069542 0.7327917670704154 0.7526129510604717 1.036094355148651 1.0743698397205261 1.090682936458799 0.9778251693317712 1.0702728335563323 0.8885038490099778 1.0 15.163338695470939 -5.759836718895945 24.96245068613005 1.0260999254489287 0.749894450878665 0.8281949480925646 0.05585672607950775 15.041900179956112 234277.91320308595 0.01524586299592209 0.024718537576247507 1.7384543101934507e-06 5.759836718895945 -0.2762054745702637 GALALEEK ddPTM_PC-9_Lapatinib_30min_R1 2 GALALEEK 8 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 139.28 0.01275 13402700.0 148828.0 177976.0 206640.0 205201.0 192763.0 191416.0 181494.0 174512.0 191722.0 160159.0 False True 146705.68542828775 177563.90750681242 189650.85685346724 220292.16607046936 181425.05932663928 183229.58389249 190890.87126303793 182620.46460737736 170128.2494378372 187842.26975154725 0.7810046461977408 0.9452819524682614 1.0096282221478272 1.1727507677683118 0.9658372397576126 0.9754438345258588 1.0162295819547058 0.972201117719262 0.9056973686639338 1.0 17.51916222059706 -4.793768228933916 2.7038919364530254 1.0048277179962621 0.7410494933556393 0.5148758859904328 0.06460582954390405 0.37651220872547053 3.7746559062855614 0.017666799380269205 0.22413828626473148 1.6077990624065612e-05 4.793768228933916 -0.26377822464062284 GALEAFAAALRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GALEAFAAALRR 12 1 Q17RB8-2;Q17RB8 Q17RB8-2 LONRF1 LON peptidase N-terminal domain and RING finger protein 1 0 54.471000000000004 0.033617 1370000.0 4333.4 3529.6 4876.4 4276.7 7573.0 5705.7 4647.5 5210.0 5963.7 5626.1 False True 5066.959031448662 3879.9953616862404 4992.671869849986 4037.0903642484745 6089.125013235367 5406.483047689201 4207.255155013796 5073.243020451303 6050.907830288053 6646.067393816904 0.7623995862820548 0.5838031924406832 0.7512219744408346 0.6074404794637408 0.9161997091543667 0.8134860402888877 0.6330443111256997 0.7633451061858234 0.9104493637722436 1.0 12.69828520727862 -14.52286513396829 0.09941809671043647 1.8880502643712889 0.5557446052675609 0.44404811401495903 0.09892535266679413 180.16371761008298 1.215680590005244 32.57864073329599 1.7366695778730352 3.0000940250860713e-15 14.52286513396829 -1.332305659103728 GALGLGS(ph)CHFTGK ddPTM_PC-9_AZD4547_30min_R2 1 GALGLGSCHFTGK 13 0 Q8NCL4 Q8NCL4 GALNT6 Polypeptide N-acetylgalactosaminyltransferase 6 1 GALGLGS(0.979)CHFT(0.021)GK 93.839 0.0039225 96107000.0 2844.2 8703.0 97541.0 160750.0 107350.0 74688.0 31920.0 119100.0 51470.0 66098.0 True False 3748.5964369648773 11516.074553559118 96247.54260784278 123691.57106274251 92446.3054958818 70017.74755309844 34760.81816276639 100695.8316457318 54190.59912191243 63783.929138665415 0.05877023393801091 0.18054821502957782 1.5089622716499935 1.9392278389410391 1.4493667408745665 1.097733371064062 0.5449776868903267 1.578702237468319 0.8495964399449709 1.0 15.960905350991466 -5.251181643313805 22.750562648752783 1.2684181222016713 0.11965834408762435 0.5838320298830613 0.3800315866787409 147.9315881808004 328089.3857785285 0.10353578580440854 0.26606866306907484 5.60813367238735e-06 5.251181643313805 -1.1487597781140468 GALHT(ph)VSHEDIR ddPTM_PC-9_AZD4547_30min_R2 2 GALHTVSHEDIR 12 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2;H0YD72 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 GALHT(0.849)VS(0.151)HEDIR;GALHT(0.916)VS(0.084)HEDIR 99.844 0.0067501 149888000.0 65805.0 87263.0 115490.0 125828.0 104376.0 132790.0 103139.0 133250.0 105437.0 103533.0 True False 86729.62117097036 115469.05822902788 113958.52714017464 96820.29862322092 89885.1940609053 124486.62030816123 112318.17119328192 112659.27428038414 111010.18456609832 99908.34118299252 0.8680918944707133 1.1557499290027675 1.1406307600628436 0.9690912438020013 0.8996765735132287 1.2460082795304452 1.1242121514915306 1.1276263117414487 1.1111202853700837 1.0 16.608317510830247 -6.762874117329915 24.999993800998045 1.1299212018404907 1.0202885203242338 0.2348025764871462 0.10193693279776017 63.51963797972133 1106804.432017109 0.03573263653183212 0.0332198197712084 1.7263382082043886e-07 6.762874117329915 -0.10963268151625694 GALHTVS(ph)HEDIR ddPTM_PC-9_AZD4547_30min_R2 3 GALHTVSHEDIR 12 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2;H0YD72 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 GALHT(0.017)VS(0.983)HEDIR;GALHT(0.259)VS(0.741)HEDIR;GALHT(0.049)VS(0.951)HEDIR 112.08 0.00056437 126876000.0 105150.0 107234.0 134644.0 168889.0 143534.0 155071.0 110252.0 163122.0 135531.0 152162.0 True False 138585.5127441309 141895.29342483735 132858.53258517315 129954.25035903897 123606.78167718623 145374.38585591488 120064.21441357517 137915.24307065498 142694.89196797978 146834.85469450816 0.9438189116096438 0.966359749666061 0.9048160456288602 0.8850368029403543 0.8418081792252374 0.9900536637460376 0.8176819779157363 0.9392541257155153 0.9718053132879 1.0 17.163834940753638 -8.229471148590818 3.1309436804383983 0.9918955083208056 0.9078101475104311 0.2777471378636811 0.05009592210224465 0.3324714071228196 6.174474215220843 0.04375504785733811 0.013016751051309132 5.895611419765506e-09 8.229471148590818 -0.08408536081037454 GALHTVS(ph)HEDIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GALHTVSHEDIR 12 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2;H0YD72 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 GALHT(0.103)VS(0.897)HEDIR;GALHT(0.006)VS(0.994)HEDIR;GALHT(0.004)VS(0.996)HEDIR 104.09 0.0011063 167891000.0 99145.0 101240.0 129111.0 121464.0 139599.0 112472.0 133371.0 102867.0 120454.0 109601.0 True False 115928.29029699003 111290.43812814904 132189.4958961941 114658.76587160124 112245.57806980667 106573.7703243599 120737.1333575782 100166.85024659557 122215.41187342035 129470.79369896122 0.8954010938292422 0.8595794846744803 1.0209985751964592 0.8855956049686377 0.8669567464828729 0.8231491232853619 0.932543393827568 0.7736636764543078 0.9439612470252503 1.0 16.982267162789917 -2.811147922309252 10.618093000417435 0.893556484487026 1.2030935868907444 0.0 0.0727272784857576 0.0 0.0 0.016016505198508325 0.0 0.001544728209775358 2.811147922309252 0.30953710240371846 GALHTVS(ph)HEDIR ddPTM_PC-9_Lapatinib_30min_R1 2 GALHTVSHEDIR 12 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2;H0YD72 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 GALHT(0.259)VS(0.741)HEDIR;GALHT(0.055)VS(0.945)HEDIR 98.337 0.0020912 142628000.0 137874.0 129560.0 143709.0 113669.0 153436.0 145815.0 132812.0 115438.0 155319.0 105718.0 True False 135907.8914770052 129260.01178014273 131893.80075278197 122028.59744866822 144411.1961467825 139578.83236136675 139688.355505893 120801.67090713793 137825.33863842138 123991.21543961977 1.0961090347822948 1.042493303431554 1.0637350419152116 0.9841713142016316 1.1646889308630632 1.125715494170131 1.126598807912463 0.9742760443054528 1.111573413888651 1.0 16.919878386253544 -9.650071009910778 0.7640810645172985 0.9974142312027421 1.0766194830335716 0.12667703676976938 0.05902856297592126 16.468219675033836 9.022230514052806 0.2017553410677226 0.020922065044494027 2.2383551233431341e-10 9.650071009910778 0.07920525183082949 GALHTVS(ph)HEDIRDIR ddPTM_PC-9_AZD4547_30min_R2 1 GALHTVSHEDIRDIR 15 1 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2;H0YD72 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 GALHT(0.009)VS(0.991)HEDIRDIR 58.658 0.024377 6964800.0 11761.0 5421.0 12336.0 40339.0 28095.0 10771.0 8761.5 12568.0 8698.0 16150.0 True False 15500.753356003075 7173.232236567156 12172.416579800794 31039.466781337313 24194.494205000512 10097.487667288244 9541.256526725489 10625.904383908943 9157.758522681068 15584.593415677422 0.9946203242241786 0.4602771496978033 0.7810544847166737 1.9916763917698976 1.5524623299226983 0.6479147320667737 0.6122236411459666 0.6818210844833299 0.5876161333454334 1.0 13.927832896730415 -6.801136821171666 24.990499543451563 0.6801726920014627 1.142960339094261 0.23628591267121302 0.40293482296799493 264.795878452435 166693.6125889857 0.16066417168645486 0.14169442905239382 1.5807499575710026e-07 6.801136821171666 0.4627876470927984 GALQGSAWQVS(ph)SEDVR ddPTM_PC-9_AZD4547_30min_R2 1 GALQGSAWQVSSEDVR 16 0 Q9Y4W2-3;Q9Y4W2-2;Q9Y4W2 Q9Y4W2-3 LAS1L Ribosomal biogenesis protein LAS1L 1 GALQGSAWQVS(0.798)S(0.202)EDVR 115.31 0.0019299 0.0 5548.5 2742.4 6633.4 6627.3 5347.7 4282.1 5886.2 5095.0 5539.2 5419.7 True False 7312.807584030527 3628.8271694450814 6545.436781813439 5099.478375764312 4605.264163021224 4014.33961007288 6410.060396919659 4307.6848214525835 5831.990803499073 5229.957952628289 1.3982536093536877 0.6938539855031594 1.2515276109483946 0.9750515055673813 0.8805547204651754 0.7675663258545882 1.2256428168219433 0.8236557273443811 1.115112369224352 1.0 12.352583632323883 -4.733948434619592 24.76176710545791 0.972590458394554 1.3982561504560973 0.3446499451261743 0.17700067081048232 3044.198453756813 2741819.920447831 0.041429960835739174 3.809603541276476 1.845234497648656e-05 4.733948434619592 0.42566569206154325 GALQGSAWQVS(ph)SEDVR ddPTM_PC-9_Lapatinib_30min_R1 1 GALQGSAWQVSSEDVR 16 0 Q9Y4W2-3;Q9Y4W2-2;Q9Y4W2 Q9Y4W2-3 LAS1L Ribosomal biogenesis protein LAS1L 1 GALQGSAWQVS(0.759)S(0.241)EDVR 130.95 8.0755e-05 0.0 5644.4 6537.0 9607.1 5070.9 5709.0 5613.9 5139.0 5094.1 7397.4 7788.9 True False 5563.909820943809 6521.863978132084 8817.24132247844 5443.830902026511 5373.2078443258515 5373.806583640074 5405.072274679886 5330.790482926346 6564.226913924622 9135.20098694312 0.6090626608978026 0.7139267091609413 0.9651940154443084 0.5959180219250064 0.5881871512193043 0.5882526932161447 0.5916752441906115 0.5835438640644698 0.7185640385260079 1.0 13.1572207551324 -8.558455326956055 18.730353221851253 1.0000000043891242 0.6578919131540001 0.46349853643338035 0.11109464161693373 406.1941276654261 213854.15379404803 0.11658003734850256 0.030100830314593693 2.7640422235637723e-09 8.558455326956055 -0.3421080912351241 GALQNIIPAS(ph)TGAAK ddPTM_PC-9_AZD4547_30min_R2 2 GALQNIIPASTGAAK 15 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 GALQNIIPAS(0.5)T(0.5)GAAK;GALQNIIPAS(0.957)T(0.043)GAAK 216.71 8.8574e-18 281690000.0 427560.0 515420.0 586620.0 697370.0 652750.0 630920.0 479890.0 629250.0 507270.0 524270.0 True False 563515.1861995303 682019.4354125519 578841.0355093016 536602.1207590961 562126.9297851607 591468.4726622887 522599.2803298848 532013.871226505 534083.2565877703 505915.46687536966 1.1138524577631663 1.3480897107669665 1.1441457583503705 1.0606556942669751 1.1111084095866128 1.1691053375286402 1.0329774726152523 1.0515864923290923 1.0556768700636299 1.0 18.948536820408044 -5.764159712757499 0.3163933731319261 1.00436879866205 1.3090838008090413 0.44151975381056074 0.07017455805691225 3.6315105905085434 0.47453075492450647 0.08332679367178414 0.4070513434576533 1.7212354704242825e-06 5.764159712757499 0.3047150021469913 GALQNIIPAS(ph)TGAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GALQNIIPASTGAAK 15 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 GALQNIIPAS(0.891)T(0.109)GAAK;GALQNIIPAS(0.917)T(0.083)GAAK 154.81 6.2826e-05 8333200.0 101071.0 112581.0 103736.0 115248.0 122348.0 101505.0 122467.0 106375.0 94105.0 96948.0 True False 118180.32405675636 123757.29765809127 106209.45966097104 108791.02819905743 98374.78768246694 96181.89911065994 110866.03917570214 103582.76896362918 95481.10759583114 114523.90496005445 1.0319271255898692 1.0806241517983288 0.927399914437222 0.9499416583551126 0.8589891142533057 0.8398412466306302 0.9680602422207996 0.9044641727834769 0.8337220742615669 1.0 16.805289242782784 -5.359917714107818 3.6760772761868963 0.9033778221895629 1.0569465610710664 0.547053355564606 0.05300187646817423 0.16304994963262093 4.0116696790760376 0.014104768129544419 0.03300920735404041 4.365985468479256e-06 5.359917714107818 0.15356873888150357 GALQNIIPAS(ph)TGAAK ddPTM_PC-9_Lapatinib_30min_R1 1 GALQNIIPASTGAAK 15 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 GALQNIIPAS(0.5)T(0.5)GAAK 207.21 5.888600000000001e-13 117430000.0 136580.0 139250.0 135960.0 93133.0 130150.0 140410.0 114560.0 111750.0 120220.0 108600.0 True False 134632.34415429583 138927.5751804943 124781.8936207772 99982.31150258055 122494.83288474513 134404.99161169655 120491.35625361507 116942.31296343195 106679.55762727695 127371.36529959609 1.0570063674643109 1.0907284761666511 0.9796699071826068 0.7849669450225921 0.9617140602726474 1.0552214094239811 0.9459846486704588 0.9181209033000982 0.8375474140231678 1.0 16.95868145231708 -5.41680734389754 4.784216264289855 0.9297470594631912 1.0711173137848589 0.382211456662074 0.07248341197142863 0.2368758072594867 8.447523416327417 0.020275893969151186 0.04357677521326616 3.829946047524565e-06 5.41680734389754 0.1413702543216676 GALQNIIPAST(ph)GAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GALQNIIPASTGAAK 15 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 GALQNIIPAS(0.09)T(0.91)GAAK;GALQNIIPAS(0.038)T(0.962)GAAK 215.15 2.7163999999999998e-17 213013000.0 387320.0 396790.0 364810.0 416900.0 447670.0 370280.0 475120.0 350920.0 365700.0 331210.0 True False 452885.62608129834 436180.68890624505 373508.4539496292 393542.4446080365 359952.277125984 350861.86495931406 430113.1940290822 341708.7218304736 371047.6706635713 391255.751143083 1.1575181317032632 1.114822434256648 0.9546401627538925 1.0058444980253267 0.9199922967888817 0.8967583580158115 1.0993146880843905 0.8733640868719398 0.948350713259876 1.0 18.577752433088136 -5.191050172419825 3.4089131225581055 0.9595203349143839 1.150723997507901 0.5710199951060172 0.06060793286149809 0.1688215419735769 3.8018867270738204 0.01567669814989959 0.04915477060753989 6.440948513437594e-06 5.191050172419825 0.19120366259351718 GALQNIIPAST(ph)GAAK ddPTM_PC-9_Lapatinib_30min_R1 1 GALQNIIPASTGAAK 15 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 GALQNIIPAS(0.192)T(0.808)GAAK 200.0 1.1673e-09 96322000.0 101480.0 89064.0 91018.0 83512.0 100000.0 90676.0 97645.0 97100.0 93176.0 69131.0 True False 100032.87659084724 88857.77778007576 83534.85137964014 89653.75106786536 94118.19660756443 86797.99885607997 102700.58031934565 101611.62048097777 82681.53769322214 81080.20123873283 1.233752199212112 1.095924484923793 1.0302743469232376 1.105741595335815 1.1608036878256196 1.070520269190152 1.2666542355630532 1.2532235851486377 1.0197500305872989 1.0 16.307062049086397 -6.247415828661052 22.347047770408956 1.1451626752856152 1.1088054669083507 0.0 0.0953981941366227 918.456995744943 1463587.9207829742 0.02845079161026451 0.03644966211261243 5.656973852203299e-07 6.247415828661052 -0.03635720837726453 GALQNIIPASTGAAK ddPTM_PC-9_AZD4547_30min_R2 2 GALQNIIPASTGAAK 15 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 174.46 0.00031751 27475000.0 134147.0 136755.0 151909.0 224910.0 184548.0 196165.0 146217.0 191234.0 167083.0 206703.0 False True 176802.9555690622 180958.37936021798 149894.58740442272 173060.47432486108 158926.69573035862 183898.7715396525 159230.02974013783 161683.17942014986 175914.66627329498 199466.39088549686 0.8863796792240326 0.9072123807769533 0.7514779143443233 0.8676172138904642 0.7967592686909849 0.9219536721112033 0.7982799961099382 0.8105785576326171 0.8819263510627127 1.0 17.605786154280104 -8.605934390957536 5.694548633344469 0.9999960937939592 0.8422791647359807 0.45965574276960397 0.05139315559256579 0.7312440115451605 49.27956816150177 0.04838306410808479 0.012550274676476717 2.4777963510539046e-09 8.605934390957536 -0.1577169290579784 GALQNIIPASTGAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GALQNIIPASTGAAK 15 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 232.6 2.6576e-25 100897000.0 86998.0 85109.0 92864.0 98115.0 100066.0 99876.0 93875.0 72438.0 85225.0 81875.0 False True 101725.04311117617 93558.05905421397 95078.22994868107 92617.93464312168 80458.78562979128 94638.32673835047 84982.4804038557 70536.5792544051 86471.25439514036 96718.2893778568 1.05176635944996 0.9673254113159868 0.9830429235284716 0.9576051772512648 0.8318880136047149 0.9784946295795165 0.8786598786073242 0.7292992846351366 0.8940527686270013 1.0 16.5615011079257 -5.714430870908778 0.7565564682191335 0.8665409563001876 1.0431628419276846 0.31966147587780414 0.07414480676496034 1.1468504648616356 1.1112775180449204 0.03631016156225723 0.14022164174274865 1.930052529038367e-06 5.714430870908778 0.17662188562749703 GALQNIIPASTGAAK ddPTM_PC-9_Lapatinib_30min_R1 2 GALQNIIPASTGAAK 15 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 202.32 4.9872e-10 255860000.0 316270.0 287570.0 330130.0 328710.0 343410.0 298740.0 335170.0 320170.0 279250.0 309210.0 False True 311759.93180318584 286904.1493332483 302987.98573865223 352884.42994441505 323211.29897003673 285963.5865969532 352523.4626005952 335046.2670380501 247797.92436713586 362656.53650357353 0.8596561771887816 0.7911180978546108 0.835468150277409 0.9730541005730302 0.8912325201309363 0.7885245619835544 0.9720587584035495 0.9238666156917557 0.683285421396766 1.0 18.468244326642996 -11.975753222420414 2.4337076119810472 2.737945809076962 0.8626504722783453 0.19963875975261158 0.08500275509829308 6589218.788780654 2037644.4026418168 66270373.91723883 0.0216793647544602 1.0574181914426357e-12 11.975753222420414 -1.875295336798617 GALS(ph)SSLR ddPTM_PC-9_AZD4547_30min_R2 1 GALSSSLR 8 0 A0A1W2PR28;Q5JU85-3;A0A1W2PQS2;A0A1W2PPE7;A0A1W2PPU7;A0A1W2PRJ5;Q5JU85 A0A1W2PR28 IQSEC2 IQ motif and SEC7 domain-containing protein 2 1 GALS(0.466)S(0.267)S(0.267)LR 85.161 0.013434 12798000.0 88489.0 112690.0 140490.0 119620.0 108590.0 127170.0 123040.0 162820.0 136830.0 118620.0 True False 116626.66131445946 149114.83872694222 138627.0108054646 92043.457110577 93514.15289984009 119218.0397965876 133990.32163993685 137659.9102313857 144062.5544560184 114467.14990511804 1.0188657742516647 1.3026867433193163 1.2110637062281424 0.8041036855278736 0.816951876388589 1.0415043957625185 1.1705569829510178 1.2026149890644797 1.2585493268193715 1.0 16.804574103599492 -9.97967268571237 12.502744586728497 1.0000048928311682 1.0891227888288488 0.02701075353227078 0.16468544670383203 0.0 0.0 0.17810788667985814 0.04319750761979977 1.0479180338440892e-10 9.97967268571237 0.08911789599768061 GALSS(ph)SLR ddPTM_PC-9_Lapatinib_30min_R1 1 GALSSSLR 8 0 A0A1W2PR28;Q5JU85-3;A0A1W2PQS2;A0A1W2PPE7;A0A1W2PPU7;A0A1W2PRJ5;Q5JU85 A0A1W2PR28 IQSEC2 IQ motif and SEC7 domain-containing protein 2 1 GALS(0.272)S(0.631)S(0.097)LR 82.426 0.016486 15707000.0 106350.0 121760.0 107870.0 101630.0 132120.0 121420.0 116150.0 135650.0 115530.0 91705.0 True False 104833.4294977985 121478.07220091236 99001.34499024147 109104.2092277413 124348.96135791406 116227.14964384444 122163.67867368514 141952.79421467156 102517.79481516629 107556.08706076848 0.974686160147945 1.1294393048370945 0.9204625018973251 1.0143936267047178 1.1561313241867726 1.0806189851270516 1.1358137136828292 1.3198025150772654 0.9531566052346662 1.0 16.71472964981499 -6.24908957661639 22.765958084916612 1.1236402269732815 1.0119175767280493 0.1636064961243694 0.1046200775503075 370.48041830369397 682950.0900120358 0.029941428045110238 0.03829615037072659 5.635214131618379e-07 6.24908957661639 -0.1117226502452322 GALSS(ph)SLRDLSDAGVCY ddPTM_PC-9_Lapatinib_30min_R1 1 GALSSSLRDLSDAGVCY 17 1 A0A1W2PR28;Q5JU85-3 A0A1W2PR28 IQSEC2 IQ motif and SEC7 domain-containing protein 2 1 GALS(0.009)S(0.896)S(0.095)LRDLSDAGVCY 118.5 0.00053913 7382900.0 15943.0 13877.0 17570.0 17992.0 16084.0 19724.0 12275.0 15143.0 16987.0 11839.0 True False 15715.649896411875 13844.868659100337 16125.462422161341 19315.191699552535 15137.970742360658 18880.45049888969 12910.53943796372 15846.59906223939 15073.745178959853 13885.355375524106 1.1318147408826174 0.9970842146038886 1.1613287514834443 1.3910477029345372 1.0902112573254374 1.359738370986925 0.9297953915332475 1.1412454801245053 1.0855858399944547 1.0 13.761276480865037 -7.276886968705308 24.998362424652676 1.0509271524242805 1.1833339685834259 0.2638935781553763 0.12140342287826685 1377.506695208954 2229168.0511998273 0.05198620875381656 0.03519186138238393 5.2858280504156034e-08 7.276886968705308 0.1324068161591454 GALSSS(ph)LR ddPTM_PC-9_AZD4547_30min_R2 1 GALSSSLR 8 0 A0A1W2PR28;Q5JU85-3;A0A1W2PQS2;A0A1W2PPE7;A0A1W2PPU7;A0A1W2PRJ5;Q5JU85 A0A1W2PR28 IQSEC2 IQ motif and SEC7 domain-containing protein 2 1 GALS(0.056)S(0.338)S(0.606)LR 87.696 0.011531999999999999 13430000.0 77836.0 110220.0 109050.0 115100.0 111250.0 134670.0 127950.0 158340.0 128710.0 100300.0 True False 102586.22891062427 145846.45953042485 107603.92574799567 88565.47327727321 95804.85781478234 126249.0636109656 139337.30212800612 133872.19129122747 135513.347833327 96788.52752894384 1.059900708582912 1.506856889488381 1.111742563867578 0.9150410233360395 0.9898369182869597 1.3043804553510934 1.4396055574493414 1.383141108859147 1.4000972149597255 1.0 16.56254843264867 -6.910382484409738 7.748524894378453 1.3424067847305499 1.1274205735041534 0.19424039137178084 0.1856209986281644 0.37771083486193296 28.32850571537237 0.06827840099162193 0.0602082040298341 1.229185746519264e-07 6.910382484409738 -0.2149862112263965 GALSSS(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 1 GALSSSLR 8 0 A0A1W2PR28;Q5JU85-3;A0A1W2PQS2;A0A1W2PPE7;A0A1W2PPU7;A0A1W2PRJ5;Q5JU85 A0A1W2PR28 IQSEC2 IQ motif and SEC7 domain-containing protein 2 1 GALS(0.011)S(0.07)S(0.919)LR 107.01 0.0038169000000000002 13748000.0 132000.0 176360.0 144420.0 129270.0 156410.0 163070.0 134270.0 150360.0 201620.0 118070.0 True False 130117.65579416473 175951.64925552608 132546.34507732146 138776.9470320787 147210.27131389137 156095.87623473632 141221.84361184423 157346.2745161667 178911.43244727634 138478.24218161398 0.9396252706870415 1.2706086276338329 0.957163688599449 1.0021570525864487 1.0630570477694636 1.1272231202214196 1.019812509077289 1.1362526851677344 1.2919822611023204 1.0 17.0792997910538 -7.924318127339565 6.322545283144381 1.16784198224226 1.0604778263026233 0.11053612333457241 0.11071822040909597 0.37398096960699717 24.187228059830876 0.05875358674436191 0.027718554584732952 1.1903697245859937e-08 7.924318127339565 -0.10736415593963677 GALSSS(ph)LRDLSDAGVCY ddPTM_PC-9_AZD4547_30min_R2 3 GALSSSLRDLSDAGVCY 17 1 A0A1W2PR28;Q5JU85-3 A0A1W2PR28 IQSEC2 IQ motif and SEC7 domain-containing protein 2 1 GALS(0.034)S(0.164)S(0.801)LRDLSDAGVCY;GALSS(0.013)S(0.987)LRDLSDAGVCY;GALSS(0.018)S(0.982)LRDLSDAGVCY 128.9 0.00015122 26601100.0 32501.1 28255.699999999997 44750.0 75722.0 61552.0 50546.0 37889.0 52093.0 37427.5 45443.0 True False 42835.77373512381 37388.802454670855 44156.58576086943 58265.46279323793 53006.56726485821 47385.35062953783 41261.047599281184 44043.22382805292 39405.84124024435 43852.054401772715 0.9768247877890113 0.852612334010956 1.006944517497552 1.328682625890443 1.2087590419188075 1.0805731060030401 0.9409148137336346 1.0043594177944026 0.8986087830505696 1.0 15.420356811861918 -7.255033407953686 22.878652821872876 0.9613340383124381 1.0800085496642724 0.16998089456539922 0.12401924472836846 339.5473179728105 1212683.636558032 0.05575173873580749 0.04200598592155633 5.558614961712761e-08 7.255033407953686 0.11867451135183427 GALSSS(ph)LRDLSDAGVCY ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GALSSSLRDLSDAGVCY 17 1 A0A1W2PR28;Q5JU85-3 A0A1W2PR28 IQSEC2 IQ motif and SEC7 domain-containing protein 2 1 GALS(0.007)S(0.076)S(0.917)LRDLSDAGVCY 90.259 0.011662 6954200.0 11294.0 8092.6 10769.0 16674.0 16199.0 13699.0 13929.0 13765.0 12970.0 10877.0 True False 13205.851133332078 8895.979845869804 11025.773801659936 15739.809837837376 13024.922235494492 12980.600324288758 12609.544282772924 13403.683335223068 13159.661713170686 12848.913997715383 1.0277795567532138 0.6923526647817524 0.8581093938071643 1.2249914538019333 1.0136982968218484 1.0102488293249368 0.9813704321637595 1.043176360088201 1.0241847455365143 1.0 13.649358806180977 -5.562259903393078 24.73020624729979 1.0394080679083662 0.8388572835906266 0.4140593276081759 0.09913374189623503 113.72608825133031 71416.09213066811 0.025887817217725703 0.044839110610991904 2.7399339685845893e-06 5.562259903393078 -0.20055078431773954 GALSSS(ph)LRDLSDAGVCY ddPTM_PC-9_Lapatinib_30min_R1 1 GALSSSLRDLSDAGVCY 17 1 A0A1W2PR28;Q5JU85-3 A0A1W2PR28 IQSEC2 IQ motif and SEC7 domain-containing protein 2 1 GALS(0.007)S(0.258)S(0.735)LRDLSDAGVCY 115.38 0.00074349 7031100.0 14055.0 13182.0 22263.0 21774.0 18483.0 17656.0 14613.0 12526.0 19280.0 16583.0 True False 13854.573122628677 13151.47788889966 20432.622077665215 23375.332595934702 17395.866278976122 16900.894038146238 15369.589638041867 13108.00368841119 17108.4833725994 19449.349454541458 0.7123412099212197 0.6761911456030097 1.0505555533063942 1.2018567844939678 0.8944189274625921 0.8689696319996888 0.7902366952665885 0.6739558934373739 0.8796429624850274 1.0 14.24743428003583 -6.980797946925931 3.245742907932787 0.8100142797444516 0.9177712415235756 0.029733499492200166 0.16104452342810915 0.7505688159449825 16.450571096359152 0.06924249669380679 0.05707372836645399 1.0452063825321487e-07 6.980797946925931 0.10775696177912397 GANPVEIR ddPTM_PC-9_Lapatinib_30min_R1 2 GANPVEIR 8 0 P10809;E7ESH4;E7EXB4;P10809-2 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 ; 95.815 0.029077 18347100.0 119170.0 125677.0 165419.0 131278.0 144154.0 156556.0 152854.0 114625.0 185401.0 123007.0 False True 117470.61394689845 125386.00262807186 151818.88835580548 140932.6220505702 135675.14513766844 149860.46482986072 160768.03219963395 119950.89595913567 164519.18702091786 144268.59605347508 0.8142493734627901 0.8691150122622381 1.0523349676150713 0.9768766447157471 0.9404343623568544 1.0387601247212037 1.1143660962781057 0.8314414865080844 1.140367283812318 1.0 17.13839776699892 -5.121917594046841 4.33720270357161 1.0063249522111395 0.8255618403088476 0.40551193837776545 0.08312193566416522 0.20868767515332115 6.246661007517649 0.020307952725680613 0.06128674364293665 7.552355175323772e-06 5.121917594046841 -0.18076311190229188 GANPVEIRR ddPTM_PC-9_AZD4547_30min_R2 1 GANPVEIRR 9 1 P10809;E7ESH4;E7EXB4;P10809-2 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 103.55 0.0017851 1479900.0 9058.7 3190.0 12395.0 33010.0 18296.0 10599.0 6514.2 10583.0 6871.5 12781.0 False True 11939.178167334843 4221.105116150014 12230.634201250874 25400.054499416045 15755.916211948355 9936.24285447852 7093.95118032245 8947.64052314675 7234.713461554715 12333.541080233625 0.9680251672789408 0.3422460012651984 0.9916563395448794 2.0594291885988443 1.2774852014884523 0.8056277422550495 0.5751755423826809 0.7254721466397599 0.5865885080765202 1.0 13.590299450615712 -6.903929116544023 5.558389328438724 0.6979629102120462 1.1263845180741807 0.18551909382630216 0.4089157667408709 0.3987849900968542 18.85967427585631 0.16414144794644808 0.14443545760524257 1.247587122794618e-07 6.903929116544023 0.42842160786213457 GANPVEIRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GANPVEIRR 9 1 P10809;E7ESH4;E7EXB4;P10809-2 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 88.49600000000001 0.020138 0.0 5436.7 2100.8 4217.8 8629.7 8997.5 12249.0 7007.2 12422.0 8778.6 7445.9 False True 6357.025930280371 2309.353540296479 4318.368348095575 8146.205886864884 7234.504464094177 11606.64087686787 6343.427288265232 12095.935662196936 8906.970417520455 8795.782728288028 0.7227356707931863 0.2625523630625152 0.49095896084464596 0.9261490578508668 0.822496949683325 1.319568847413644 0.7211896296465122 1.375197186635286 1.0126410227113543 1.0 13.102596252123178 -5.919599822437197 1.8756609020547947 1.0663483203996587 0.4545284645572346 0.5666664293018582 0.21394345691547756 0.22766133616241827 1.6266051456374402 0.06533937853592432 0.11354874458871982 1.2033727631857052e-06 5.919599822437197 -0.611819855842424 GANPVEIRR ddPTM_PC-9_Lapatinib_30min_R1 2 GANPVEIRR 9 1 P10809;E7ESH4;E7EXB4;P10809-2 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 ; 91.867 0.0047266999999999995 2815400.0 106445.0 20403.0 20633.0 17192.8 10201.1 12472.2 7781.9 7193.700000000001 21491.0 8661.3 False True 104927.07478037749 20355.758107056587 18936.634385683257 18457.215865499493 9601.09135413425 11938.793080118228 8184.808704870862 7527.9455638929885 19070.45726973723 10158.394164543197 10.329100552783665 2.003836214399537 1.8641366025921284 1.816942281086361 0.945138690093937 1.1752638150023087 0.8057187555725169 0.7410566514704153 1.8773102284513286 1.0 13.310384738947484 -4.755582557450026 4.2215413785337255 1.288082655151007 11.277587806939808 0.977004909848506 0.41415164882495625 0.03481710047151142 1.2326797579840256 0.11630322134336078 1.0897147610764344 1.7555671369702264e-05 4.755582557450026 9.989505151788801 GAPGSPT(ph)QERPAGGLGEAPNGAPSVCAEEGSLGPR ddPTM_PC-9_AZD4547_30min_R2 4 GAPGSPTQERPAGGLGEAPNGAPSVCAEEGSLGPR 35 1 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 GAPGS(0.046)PT(0.954)QERPAGGLGEAPNGAPSVCAEEGSLGPR;GAPGS(0.062)PT(0.938)QERPAGGLGEAPNGAPSVCAEEGSLGPR;GAPGS(0.014)PT(0.986)QERPAGGLGEAPNGAPSVCAEEGSLGPR;GAPGS(0.075)PT(0.925)QERPAGGLGEAPNGAPSVCAEEGSLGPR 129.72 1.1302e-22 141294000.0 25011.5 24207.0 43550.299999999996 50034.7 44879.2 45372.0 34197.799999999996 42382.600000000006 27185.399999999998 36719.3 True False 32964.63672848147 32031.439356314568 42972.79456673945 38499.97294340906 38648.49775138133 42534.88166745916 37241.33795008308 35833.34302525937 28622.364743905906 35433.76848348506 0.9303169868552253 0.9039806017596959 1.2127638804991396 1.0865333999501943 1.0907250175604266 1.2004052486622692 1.0510126228160148 1.0112766594939102 0.8077708346840442 1.0 15.112837287944346 -8.027107516634207 4.401014448698514 0.9020972338092117 1.0722668335279169 0.2857662284445147 0.10219249103823436 0.26495666545825175 12.020739889761577 0.07319353082831155 0.028085310873763928 9.394906956313527e-09 8.027107516634207 0.17016959971870516 GAPGSPT(ph)QERPAGGLGEAPNGAPSVCAEEGSLGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GAPGSPTQERPAGGLGEAPNGAPSVCAEEGSLGPR 35 1 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 GAPGS(0.013)PT(0.987)QERPAGGLGEAPNGAPSVCAEEGSLGPR;GAPGS(0.061)PT(0.939)QERPAGGLGEAPNGAPSVCAEEGSLGPR;GAPGS(0.089)PT(0.91)QERPAGGLGEAPNGAPS(0.001)VCAEEGSLGPR;GAPGS(0.162)PT(0.838)QERPAGGLGEAPNGAPSVCAEEGSLGPR 115.63 5.6455000000000005e-24 104426000.0 24951.3 16434.5 36776.7 28226.5 32287.0 32904.4 30711.0 24795.1 29591.3 25725.0 True False 29175.062279361475 18066.00854817331 37653.596004411454 26645.060716547716 25960.594124168798 31178.83533911433 27801.83175161456 24144.254897580056 30024.01678126044 30388.738861012032 0.9600616337781732 0.5944968177455872 1.2390641209767361 0.8768070579833321 0.8542833660489797 1.0259996468335173 0.9148728375590339 0.7945132243890685 0.9879981172822042 1.0 14.89124918350749 -1.522904633770993 0.012528640719467635 1.7064659912193418 1.3916388180713265e-06 0.024530833304027055 0.15720377482522385 43478.98224190397 42.2479752092393 2388.1216448903338 3457.6437553603114 0.02999821173972013 1.522904633770993 -1.7064645995805237 GAPGSPT(ph)QERPAGGLGEAPNGAPSVCAEEGSLGPR ddPTM_PC-9_Lapatinib_30min_R1 4 GAPGSPTQERPAGGLGEAPNGAPSVCAEEGSLGPR 35 1 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 GAPGS(0.099)PT(0.872)QERPAGGLGEAPNGAPS(0.027)VCAEEGS(0.002)LGPR;GAPGS(0.191)PT(0.809)QERPAGGLGEAPNGAPSVCAEEGSLGPR;GAPGS(0.066)PT(0.933)QERPAGGLGEAPNGAPSVCAEEGSLGPR;GAPGS(0.075)PT(0.923)QERPAGGLGEAPNGAPS(0.002)VCAEEGSLGPR 98.36399999999999 3.7044e-16 119992000.0 34315.6 35358.5 40079.7 32777.4 38151.1 34159.9 25233.0 32035.8 37683.600000000006 23499.9 True False 33826.25325128965 35276.629565669755 36784.50177811608 35187.959338201064 35907.12730594851 32698.960707616185 26539.441273982786 33524.300220437726 33439.27614209991 27561.826403351544 1.2272863472928754 1.2799089962115169 1.334617715088832 1.2766918571812127 1.302784756730859 1.1863858450120692 0.962905755431199 1.2163308675495155 1.2132460183420088 1.0 14.750383871936823 -6.945872992207765 4.872518230353494 1.110683969278316 1.2849055406318468 0.5502275595367907 0.07893745937802626 0.16564724275686707 8.318816137713227 0.029071653254583555 0.025207667108131535 1.1327315779031406e-07 6.945872992207765 0.1742215713535309 GAPMDPT(ph)ESPAAPEAALPK ddPTM_PC-9_AZD4547_30min_R2 1 GAPMDPTESPAAPEAALPK 19 0 Q8N884-2;Q8N884 Q8N884-2 MB21D1 Cyclic GMP-AMP synthase 1 GAPMDPT(0.716)ES(0.284)PAAPEAALPK 97.235 0.0025875 0.0 17141.0 15999.0 16440.0 23771.0 22377.0 20242.0 14421.0 20322.0 13194.0 17846.0 True False 22591.481445051308 21170.36387250286 16221.994858294822 18290.963208288977 19270.339805136016 18976.264540084365 15704.441062821235 17181.70185310293 13891.407903915151 17221.216971899645 1.3118400100245224 1.2293186890942234 0.9419772647173958 1.0621179233810751 1.118988271071666 1.1019119363659655 0.9119239998222323 0.9977054398152471 0.8066449616529517 1.0 14.07189947683051 -1.5228787452803376 0.3906680163881827 0.9521431734795978 6.5116374587467964 0.5969352362771869 0.09056155574624185 52.54231943290488 0.7069050262880057 0.07076679850246816 223.1348896732458 0.029999999999999995 1.5228787452803376 5.559494285267199 GAPMDPT(ph)ESPAAPEAALPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GAPMDPTESPAAPEAALPK 19 0 Q8N884-2;Q8N884 Q8N884-2 MB21D1 Cyclic GMP-AMP synthase 1 GAPMDPT(0.714)ES(0.286)PAAPEAALPK 128.64 4.3289e-06 0.0 13133.0 11064.0 12128.0 10527.0 12774.0 11455.0 12289.0 8989.7 10731.0 7662.4 True False 15356.157511426432 12162.36080057133 12417.177515696136 9937.206318994486 10271.02639892627 10854.279634624989 11124.896955344722 8753.729900374487 10887.920573942532 9051.532464474973 1.6965257067458526 1.3436797413372366 1.3718315174176845 1.0978479454164876 1.134727897097813 1.1991648571361095 1.2290622608941848 0.9670992105182976 1.2028814586563026 1.0 13.143946352187436 -1.5228787453570407 0.537845503302182 1.1037641989756786 24.99190335077372 0.7886779577369225 0.09200887544181821 55.20253607544057 0.525181243361373 0.045312629232362706 1515.9530739635074 0.029999999994701536 1.5228787453570407 23.88813915179804 GAPPGS(ph)PEPPALLAAPLAAGACPGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GAPPGSPEPPALLAAPLAAGACPGGR 26 0 Q9Y4B5 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 GAPPGS(1)PEPPALLAAPLAAGACPGGR 109.44 2.7870999999999996e-10 3502100.0 8670.3 9364.1 10621.0 11553.0 12972.0 13327.0 14176.0 14078.0 15557.0 9634.0 True False 10138.010543769178 10293.705962819053 10874.244920366806 10905.722865331354 10430.229720281153 12628.108659157335 12833.146654647786 13708.467416873984 15784.491694047529 11380.567937297961 0.8908176287532625 0.9044984415130202 0.9555098638555846 0.9582758018244081 0.9164946580651543 1.1096202517073652 1.1276367511140841 1.204550378540135 1.386968715534523 1.0 13.474284935425775 -7.007480978165161 1.4978331156640978 1.2124278753158495 0.9210827293641376 0.6293603690169474 0.09252639942811217 0.243009686358958 1.1044655090082989 0.04534442619370158 0.033428489481013214 9.829219234411836e-08 7.007480978165161 -0.2913451459517119 GAPPGS(ph)PEPPALLAAPLAAGACPGGR ddPTM_PC-9_Lapatinib_30min_R1 1 GAPPGSPEPPALLAAPLAAGACPGGR 26 0 Q9Y4B5 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 GAPPGS(1)PEPPALLAAPLAAGACPGGR 113.79 7.4473e-12 3420600.0 10167.0 7677.8 8501.4 7955.3 11463.0 9642.5 7359.1 7493.0 11024.0 6263.9 True False 10022.016715600545 7660.0225258226255 7802.447708353005 8540.359300102837 10788.768877125101 9230.11275276535 7740.118189647157 7841.152134541359 9782.361032133596 7346.606768877898 1.3641694772689301 1.0426612947724978 1.062047820689977 1.1624903263207145 1.4685376822983205 1.256377677905188 1.0535636972481328 1.0673161612186026 1.3315482017595084 1.0 12.842862340315165 -10.666584139581316 4.133745140405038 0.9999561448678564 1.192327402150131 0.1485751843933324 0.14298700186106075 107050096.93649659 56807546.8253838 60978.18071855306 0.03738710421372775 2.1548441267556543e-11 10.666584139581316 0.19237125728227467 GAPS(ph)SPATGVLPS(ph)PQGK ddPTM_PC-9_Lapatinib_30min_R1 1 GAPSSPATGVLPSPQGK 17 0 Q5SRE5-2;Q5SRE5 Q5SRE5-2 NUP188 Nucleoporin NUP188 homolog 2 GAPS(0.499)S(0.499)PAT(0.003)GVLPS(0.999)PQGK 127.32 0.00011097 0.0 16877.0 17913.0 20004.0 12977.0 14484.0 16347.0 15682.0 15229.0 19122.0 10121.0 True False 16636.330885137253 17871.52354907144 18359.348337673047 13931.371870002955 13632.079596639634 15647.876916718207 16493.937227384693 15936.594936197826 16968.278996413148 11870.401364615202 1.4014969143949032 1.5055534349786306 1.5466493317067544 1.1736226469587925 1.1484093231485724 1.3182264386917348 1.3895012241584277 1.3425489540483146 1.4294612688492865 1.0 13.535081096075217 -11.754649611443366 1.9218816260673977 4.515474241303926e-05 1.358556525214874 0.44786453862687414 0.12044135082898556 1376667.1304214015 231745.7795185374 5968839.829201541 0.036483109992630276 1.7593424780863674e-12 11.754649611443366 1.358511370472461 GAPSITSVT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 GAPSITSVTPR 11 0 H7C3L4;E7EQA9;Q92844 H7C3L4 TANK TRAF family member-associated NF-kappa-B activator 1 GAPSITS(0.001)VT(0.999)PR 90.434 0.021369 3325900.0 10431.0 10309.0 15570.0 24004.0 13866.0 11726.0 18285.0 16378.0 17829.0 13951.0 True False 13747.841021721622 13641.182646517398 15363.531626742726 18470.24865810309 11940.94524458221 10992.771366319004 19912.329577261375 13847.15642899911 18771.404541375097 13462.57973635392 1.0211891993179725 1.0132666185575996 1.14120264671529 1.371969490232739 0.8869730377408471 0.8165427118425509 1.4790872156166888 1.0285663446513664 1.394339339783845 1.0 13.716667269158428 -7.258508741167454 24.99950240397752 1.2278787441474461 1.0530383249213222 0.17494522908194587 0.19443844184217834 507.03104785654403 4325197.212148628 0.07699915015899454 0.057028475504894836 5.5143110346079505e-08 7.258508741167454 -0.17484041922612392 GAPSS(ph)PATGVLPS(ph)PQGK ddPTM_PC-9_Lapatinib_30min_R1 2 GAPSSPATGVLPSPQGK 17 0 Q5SRE5-2;Q5SRE5 Q5SRE5-2 NUP188 Nucleoporin NUP188 homolog 2 GAPS(0.09)S(0.877)PAT(0.033)GVLPS(1)PQGK;GAPS(0.107)S(0.886)PAT(0.007)GVLPS(0.999)PQGK 162.42 0.00037487 4247500.0 40930.0 37783.0 39604.0 35640.0 36201.0 42610.0 39047.0 30913.0 43268.0 32277.0 True False 40346.330694357275 37695.5157848806 36347.91199586096 38261.08449155472 34071.72835390438 40787.669628761396 41068.66260156167 32349.3308334548 38394.70220776092 37856.036443600926 1.0657832801504845 0.9957597077295856 0.9601615861188527 1.0106996951082623 0.9000342231988675 1.077441630465675 1.0848643032861354 0.8545356004622886 1.014229322844258 1.0 15.208235747207524 -4.770933504505403 4.488402137807524 0.9863921470476903 1.0717772506644379 0.10685539810521794 0.06713843128136683 0.4640513008511377 20.560402631605832 0.016823404601754355 0.12656577505232808 1.6945972429694173e-05 4.770933504505403 0.08538510361674756 GAPSS(ph)PATGVLPSPQGK ddPTM_PC-9_AZD4547_30min_R2 2 GAPSSPATGVLPSPQGK 17 0 Q5SRE5-2;Q5SRE5 Q5SRE5-2 NUP188 Nucleoporin NUP188 homolog 1 GAPS(0.009)S(0.991)PATGVLPSPQGK;GAPS(0.018)S(0.973)PAT(0.009)GVLPSPQGK 230.96 1.4375e-29 90155000.0 429750.0 382470.0 514710.0 644160.0 532600.0 455210.0 455170.0 536120.0 437720.0 476290.0 True False 566401.5606447004 506095.9478915031 507884.60909445985 495658.8641727911 458657.68334519456 426745.64673904696 495679.2482188712 453274.9728120036 460856.9855769094 459615.2320713938 1.2323385325852714 1.1011296244700812 1.105021273567296 1.0784213176289998 0.9979166296950521 0.9284845604785329 1.0784656678695006 0.9862052890831838 1.002701724004923 1.0 18.810067085453298 -3.81181813186655 0.5293636575690168 0.9955648842097637 1.7469336213952968 0.7507706689246789 0.040796836764901916 5.5342213994475875 0.543682879869969 0.022845117953634805 3.21691763764645 0.00015423462011960118 3.81181813186655 0.7513687371855331 GAPSS(ph)PATGVLPSPQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GAPSSPATGVLPSPQGK 17 0 Q5SRE5-2;Q5SRE5 Q5SRE5-2 NUP188 Nucleoporin NUP188 homolog 1 GAPS(0.001)S(0.999)PATGVLPSPQGK;GAPS(0.053)S(0.945)PAT(0.002)GVLPSPQGK;GAPS(0.096)S(0.662)PAT(0.242)GVLPSPQGK;GAPS(0.007)S(0.992)PAT(0.001)GVLPSPQGK 311.7 4.950099999999998e-130 90376000.0 396888.0 447190.0 448337.0 505479.0 511443.0 460553.0 516345.0 444954.0 466449.0 403685.0 True False 464073.29950468283 491584.0678242495 459027.0544075412 477158.65041502996 411229.4155742949 436400.78992277983 467433.0635859287 433274.4289677335 473269.9341901897 476869.89493129856 0.9731654366051786 1.030855738744151 0.9625834201038672 1.0006055225687354 0.8623513875488821 0.9151359617399437 0.9802108888699518 0.9085799577055588 0.9924508534101791 1.0 18.863236181882336 GAPSS(ph)PATGVLPSPQGK ddPTM_PC-9_Lapatinib_30min_R1 3 GAPSSPATGVLPSPQGK 17 0 Q5SRE5-2;Q5SRE5 Q5SRE5-2 NUP188 Nucleoporin NUP188 homolog 1 GAPS(0.031)S(0.938)PAT(0.031)GVLPSPQGK;GAPS(0.019)S(0.98)PATGVLPSPQGK;GAPS(0.005)S(0.995)PATGVLPSPQGK 197.29 3.0246e-12 100867500.0 329832.0 296432.0 312260.0 252501.0 304468.0 310649.0 328479.0 298215.0 385561.0 253093.0 True False 325128.5351962194 295745.6299167282 286587.1881584572 271070.7658586435 286559.7908471192 297363.2664281882 345486.0353599094 312071.1575873815 342135.0600426758 296839.7878247757 1.0952997156437214 0.9963139782706846 0.9654608307685136 0.9131887872748933 0.9653685341409664 1.001763505516725 1.163880482099824 1.0513117526266287 1.1525916473321223 1.0 18.179324955379066 -7.107552286946779 6.625669101834509 1.0957919652715589 0.9824520847735738 0.4022792145801134 0.061114804933928533 0.23787854208063 12.745918472253432 0.023376504495106056 0.018100057263235214 7.806344498828645e-08 7.107552286946779 -0.11333988049798505 GAPVNIS(ph)SSDLTGR ddPTM_PC-9_AZD4547_30min_R2 4 GAPVNISSSDLTGR 14 0 P48730-2;H7BYT1;P48730;J3KRM8 P48730-2 CSNK1D Casein kinase I isoform delta 1 GAPVNIS(0.962)S(0.035)S(0.003)DLTGR;GAPVNIS(0.837)S(0.081)S(0.081)DLT(0.002)GR;GAPVNIS(0.725)S(0.065)S(0.162)DLT(0.048)GR;GAPVNIS(0.906)S(0.085)S(0.008)DLT(0.001)GR 165.89 9.557e-05 47552900.0 42303.6 50392.0 70461.0 90949.0 91126.0 71438.0 60274.0 80653.0 57443.0 71930.0 True False 55755.26483045759 66680.22853073083 69526.64110160044 69982.1131980428 78474.72784925687 66970.97056686832 65638.26923379014 68189.9320715632 60479.31970779124 69411.7525937881 0.8032539555188717 0.9606475278179085 1.0016551737064572 1.0082170609866685 1.1305683103624709 0.9648361850016417 0.9456362471917232 0.9823974978794263 0.8713123851191124 1.0 16.08289233591602 -4.760552151665971 3.299050100391872 0.9906602627803212 0.7724628181713095 0.449777851833434 0.06092029500393059 0.3410424121098875 5.598533764474657 0.016316208147320113 0.19726436207186362 1.7355928340371893e-05 4.760552151665971 -0.2181974446090117 GAPVNIS(ph)SSDLTGR ddPTM_PC-9_Lapatinib_30min_R1 3 GAPVNISSSDLTGR 14 0 P48730-2;H7BYT1;P48730;J3KRM8 P48730-2 CSNK1D Casein kinase I isoform delta 1 GAPVNIS(0.887)S(0.086)S(0.027)DLTGR;GAPVNIS(0.584)S(0.219)S(0.188)DLT(0.008)GR;GAPVNIS(0.721)S(0.215)S(0.064)DLTGR 165.89 0.00046094 34764000.0 61231.0 42577.0 51332.0 40579.1 42143.0 47274.0 38201.0 37421.0 39070.2 30675.4 True False 60357.834711609794 42478.41557242307 47111.68110725017 43563.42238190934 39664.23159632588 45252.201221076415 40178.86086107143 39159.7162720769 34669.702648554616 35977.60201759878 1.6776502970399527 1.1806905738643827 1.3094725180462292 1.210848415094477 1.1024701306363818 1.257788142715595 1.1167742875530604 1.0884470914131952 0.9636468442670417 1.0 15.134811410702236 -1.5228787452803376 0.4611352005681553 1.0756344441035546 13.392359460949683 0.7342201548759544 0.0988784930681041 50.580928399132915 0.5938642318273771 0.059652261393414285 590.6596192646779 0.029999999999999995 1.5228787452803376 12.316725016846128 GAQASS(ph)GSPALPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GAQASSGSPALPR 13 0 P42684-2;P42684-6;P42684-3;P42684;P42684-4;P42684-7;P42684-10;P42684-5 P42684-2 ABL2 Abelson tyrosine-protein kinase 2 1 GAQAS(0.16)S(0.544)GS(0.296)PALPR;GAQAS(0.078)S(0.613)GS(0.309)PALPR 118.08 0.0002488 39076000.0 36463.0 45586.0 51393.0 53956.0 53222.0 48066.0 56777.0 51400.0 54132.0 34163.0 True False 42635.46572292254 50111.47681262154 52618.40402903788 50933.020247712186 42793.53115732377 45545.334344642964 51398.671530116946 50050.804462801694 54923.578092317344 40356.481465840814 1.0564713318481629 1.2417206602869408 1.3038402288260933 1.2620778223895395 1.0603880616685022 1.128575452822719 1.2736162733518441 1.2402172499891129 1.3609605222597676 1.0 15.300512776167588 -7.274540278109317 24.355852327870185 1.2387166074369107 1.1830566987691835 0.018894047118905855 0.11465755623052969 2093.241933339545 3891521.392787411 0.04808018553666593 0.03262485947010191 5.314467088474777e-08 7.274540278109317 -0.05565990866772719 GAQASSGS(ph)PALPR ddPTM_PC-9_AZD4547_30min_R2 2 GAQASSGSPALPR 13 0 P42684-2;P42684-6;P42684-3;P42684;P42684-4;P42684-7;P42684-10;P42684-5 P42684-2 ABL2 Abelson tyrosine-protein kinase 2 1 GAQAS(0.212)S(0.135)GS(0.653)PALPR;GAQAS(0.01)S(0.032)GS(0.958)PALPR 105.19 0.0012562 46334000.0 24428.0 26013.0 42361.0 53727.0 42503.0 37356.0 40981.0 55164.0 39726.0 45995.0 True False 32195.59586603547 34421.19353805968 41799.265461814306 41341.070223875366 36602.19210518374 35020.12341465231 44628.229609283466 46639.671342612455 41825.8352577636 44384.72904978843 0.7253755189069683 0.7755188389107391 0.9417488031734093 0.9314255400207839 0.8246573289683788 0.789012891694542 1.0054861337380676 1.0508044622801358 0.9423474278922735 1.0 15.437775769779353 -2.450693604050779 0.22018617490378367 1.020443123341485 6.373564019053035e-14 0.5318994544005804 0.07252246482552832 30.947509006909886 0.5643428623284567 0.13083234145424813 10.313550890646248 0.003542471752983729 2.450693604050779 -1.0204431233414213 GAQASSGS(ph)PALPR ddPTM_PC-9_Lapatinib_30min_R1 1 GAQASSGSPALPR 13 0 P42684-2;P42684-6;P42684-3;P42684;P42684-4;P42684-7;P42684-10;P42684-5 P42684-2 ABL2 Abelson tyrosine-protein kinase 2 1 GAQAS(0.04)S(0.176)GS(0.784)PALPR 106.42 0.00112 21237000.0 26683.0 26557.0 24323.0 20420.0 23314.0 19551.0 18279.0 16664.0 23310.0 16967.0 True False 26302.49552693709 26495.508898157223 22323.256829495174 21921.754919123097 21942.71635708757 18714.849305606996 19225.397180166092 17438.270274922877 20684.582334818042 19899.7233428936 1.321751819043755 1.3314511182698952 1.1217872954734842 1.1016110395801852 1.1026643928154682 0.9404577633130897 0.9661137920810181 0.8763071714336302 1.0394406986670355 1.0 14.280460753302801 -5.481499425604311 0.7027634507835584 0.9541437177551687 1.427357934242581 0.8478361436157584 0.05603837485186441 0.4949143983717844 0.3410700592894657 0.027399888312782374 0.16224566564088738 3.2998984435344802e-06 5.481499425604311 0.47321421648741235 GAQPGRHS(ph)VTGYGDCAVGAR ddPTM_PC-9_AZD4547_30min_R2 2 GAQPGRHSVTGYGDCAVGAR 20 1 Q96IF1;H0YJL9 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 GAQPGRHS(0.986)VT(0.013)GY(0.001)GDCAVGAR;GAQPGRHS(0.903)VT(0.093)GY(0.004)GDCAVGAR 56.403999999999996 0.0098398 104294000.0 20395.0 14365.2 25193.4 37116.0 26006.0 27654.7 22747.7 34163.0 30266.0 28183.0 True False 26880.18575764668 19008.469973203202 24859.31905492487 28559.479636483695 22395.51579623573 25925.44723726267 24772.20123186594 28883.89333764175 31865.798970736374 27196.321748237584 0.9883757813458215 0.6989353247534298 0.9140691629203805 1.0501228769414175 0.8234759098511929 0.9532703531477645 0.910865868597516 1.0620514643497159 1.1716951750212834 1.0 14.731123922406896 -7.792980432367193 3.9323771155722635 1.095189427816089 0.9009438187629307 0.3973653550627516 0.09728369942777639 0.21107254162718717 6.958676745583113 0.055587616466156814 0.02634010128770906 1.6107182062877415e-08 7.792980432367193 -0.19424560905315824 GAQPGRHS(ph)VTGYGDCAVGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GAQPGRHSVTGYGDCAVGAR 20 1 Q96IF1;H0YJL9 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 GAQPGRHS(0.932)VT(0.067)GY(0.001)GDCAVGAR;GAQPGRHS(0.974)VT(0.024)GY(0.001)GDCAVGAR 67.877 0.0025203000000000005 75511000.0 14321.8 12057.1 14466.8 11436.3 16744.4 15091.2 12529.0 14259.2 8710.1 8569.900000000001 True False 16746.197871556156 13254.049205402065 14811.743377644523 10795.561187984853 13463.455020681153 14299.790905460735 11342.162417895188 13884.911108871253 8837.468734609718 10123.555030708927 1.6541815420332102 1.3092287408125955 1.4630970378206454 1.0663804518509015 1.3299137486624935 1.4125266136336059 1.1203734640143428 1.371544982642222 0.8729610011307315 1.0 13.305428381492591 -1.5228787453745574 0.13436727162237264 0.9111569366014012 2.9871577237540934 0.4842030676748499 0.162829509839366 74.5157427289888 0.6754695736524008 0.7728977398119108 29.46474558293646 0.029999999993491528 1.5228787453745574 2.076000787152692 GAQPGRHS(ph)VTGYGDCAVGAR ddPTM_PC-9_Lapatinib_30min_R1 1 GAQPGRHSVTGYGDCAVGAR 20 1 Q96IF1;H0YJL9 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 GAQPGRHS(0.978)VT(0.019)GY(0.003)GDCAVGAR 46.065 0.037012 47092000.0 7607.5 10803.0 14506.0 10954.0 7776.6 9726.2 9920.3 10190.0 11310.0 8643.4 True False 7499.015654955366 10777.986317234348 13313.372674779297 11759.593701472799 7319.195677383857 9310.23309887958 10433.924593599306 10663.464600423913 10036.148700420083 10137.40017339344 0.7397375586136214 1.0631903775015399 1.3132926043229007 1.160020666081325 0.7219992850429022 0.9184044172701362 1.0292505391060838 1.051893426128247 0.9900120868031725 1.0 13.307400087327698 GAS(ph)GSIFSK ddPTM_PC-9_AZD4547_30min_R2 2 GASGSIFSK 9 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 GAS(0.973)GS(0.027)IFSK;GAS(0.957)GS(0.043)IFSK 109.16 0.0023875 20712000.0 29234.0 40982.0 61580.0 84855.0 99050.0 78532.0 76682.0 106665.0 81924.0 84500.0 True False 38529.803895025376 54228.63005331034 60763.408964342765 65292.99074668129 85298.6172274533 73621.38162542746 83506.5494472824 90182.37516785883 86254.33538883926 81541.68071979833 0.47251667558123234 0.665041848225525 0.745182199188953 0.8007314807631644 1.0460738173960988 0.902868091208625 1.0240964953155178 1.105966597349796 1.0577944264508727 1.0 16.315250073206037 -5.039096317071309 0.5269096964271086 1.0646410883050939 0.1986949399498717 0.9133144781405866 0.057590347839634536 0.8841670912288726 0.22826237430525287 0.0358279692659874 0.4566793345701785 9.139105335118213e-06 5.039096317071309 -0.8659461483552222 down GAS(ph)GSIFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GASGSIFSK 9 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 GAS(0.987)GS(0.011)IFS(0.003)K;GAS(0.69)GS(0.308)IFS(0.001)K;GAS(0.984)GS(0.016)IFSK 106.16 0.0025881 21240800.0 49594.0 64472.0 87050.0 86865.0 101927.0 104557.0 92293.0 88955.0 85951.0 76507.0 True False 57989.28467385082 70872.35407939572 89125.6021389633 81998.23567012964 81955.13603909186 99073.84685792115 83550.3388965442 86620.02550561354 87207.87077168352 90377.11347092102 0.641636830905304 0.7841847494078135 0.986152342292273 0.9072898272692976 0.9068129407060678 1.0962271647434094 0.9244634585881818 0.9584287678482193 0.9649331276744393 1.0 16.4636698594651 -4.994426358880842 2.149438738818622 0.9669365799701904 0.6162736008634059 0.7982618620755466 0.05343329271721956 0.18392648187156332 1.3399329889529232 0.014569518706603876 0.10581559609720351 1.0129164893805223e-05 4.994426358880842 -0.35066297910678457 GAS(ph)GSIFSK ddPTM_PC-9_Lapatinib_30min_R1 2 GASGSIFSK 9 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 GAS(0.972)GS(0.028)IFSK;GAS(0.996)GS(0.004)IFSK 87.184 0.011086 13356400.0 69491.0 71352.0 80707.0 59486.0 67143.0 65752.0 60724.0 50735.0 63409.0 47756.0 True False 68500.04559691141 71186.78882785387 74071.5819980293 63860.79887947881 63193.780748216916 62939.94023539821 63867.99159518605 53092.33331722352 56267.21069362835 56010.56096912994 1.2229844588534833 1.2709529702280302 1.3224574208220061 1.1401563879118353 1.1282475957176359 1.1237155841036368 1.1402848050457255 0.9478986176640011 1.0045821666496049 1.0 15.773411257099657 -6.80711764808831 0.5951599151572327 0.9758953325452271 1.2816352169218834 0.7855823014723136 0.05311913251639899 0.3911791917915249 0.300666303847041 0.04627245722176442 0.05049671708874979 1.5591300854838772e-07 6.80711764808831 0.30573988437665633 GAS(ph)PLGPGSAAGSGAAASGGLGLGLGGR ddPTM_PC-9_AZD4547_30min_R2 2 GASPLGPGSAAGSGAAASGGLGLGLGGR 28 0 B4E1M0;E9PPE2;A0A6I8PS01;Q6P1R3-3;Q6P1R3 B4E1M0 MSANTD2 Myb/SANT-like DNA-binding domain-containing protein 2 1 GAS(0.997)PLGPGS(0.003)AAGSGAAASGGLGLGLGGR;GAS(0.945)PLGPGS(0.055)AAGSGAAASGGLGLGLGGR 196.92 5.517699999999999e-32 9817600.0 13760.6 18260.7 25658.8 29086.0 27398.0 28102.0 22570.0 31060.0 21052.6 20817.6 True False 18136.18456173929 24163.114167548774 25318.547546837905 22380.67207422039 23594.26062390474 26344.777497552168 24578.686276116438 26260.39068779534 22165.397456265277 20088.782160384293 0.9028015942899921 1.2028162769965813 1.2603326246807969 1.114088046529559 1.1744993019254977 1.3114173515956031 1.22350305159794 1.307216658438442 1.1033718858267145 1.0 14.294102485958662 -4.761411367710232 23.41877591451514 1.2025872546822127 0.90280182591091 0.45459367153006347 0.09277374701920901 0.2568854404291246 205417.23267383914 0.021857828510915625 0.12190319599619714 1.7321625002739215e-05 4.761411367710232 -0.29978542877130276 GAS(ph)PLGPGSAAGSGAAASGGLGLGLGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GASPLGPGSAAGSGAAASGGLGLGLGGR 28 0 B4E1M0;E9PPE2;A0A6I8PS01;Q6P1R3-3;Q6P1R3 B4E1M0 MSANTD2 Myb/SANT-like DNA-binding domain-containing protein 2 1 GAS(1)PLGPGSAAGSGAAASGGLGLGLGGR;GAS(0.914)PLGPGS(0.083)AAGS(0.003)GAAASGGLGLGLGGR 125.08 2.4579999999999997e-11 9293600.0 21846.4 22136.9 31887.0 26713.0 26339.0 29476.0 26980.0 26118.0 22444.0 17822.5 True False 25544.5640339318 24334.505134324598 32647.307012120906 25216.357214714506 21178.062026093554 27930.226670467586 24424.25908171539 25432.430174308458 22772.201040123593 21053.578167167638 1.2133122375258618 1.1558370240491214 1.5506773600619255 1.197723114545849 1.0059127174458184 1.3266261178360577 1.1601001448677364 1.207986118671718 1.0816309160993873 1.0 14.361777827346176 -8.477704022519932 0.360437175333841 0.9767012182005388 1.276854443937913 0.26162426218797785 0.13129811346995765 2.3028285617659154 0.8448754036774153 0.24682804456176996 0.14004100879269724 3.3288634248623086e-09 8.477704022519932 0.30015322573737424 GAS(ph)PLGPGSAAGSGAAASGGLGLGLGGR ddPTM_PC-9_Lapatinib_30min_R1 2 GASPLGPGSAAGSGAAASGGLGLGLGGR 28 0 B4E1M0;E9PPE2;A0A6I8PS01;Q6P1R3-3;Q6P1R3 B4E1M0 MSANTD2 Myb/SANT-like DNA-binding domain-containing protein 2 1 GAS(0.996)PLGPGS(0.004)AAGSGAAASGGLGLGLGGR;GAS(0.967)PLGPGS(0.033)AAGSGAAASGGLGLGLGGR 203.75 3.7723e-38 10668800.0 17115.5 17415.2 23614.0 16589.9 16773.4 18073.1 16406.0 16208.7 18976.4 15115.7 True False 16871.4298314017 17374.87617438671 21672.548072676025 17809.976588284047 15786.8215897732 17300.15564345383 17255.422404825495 16961.815374768506 16839.078001649137 17728.428604595796 0.9516596314141494 0.9800573170868944 1.2224742844415315 1.0045998427445009 0.8904805914767163 0.9758425875922841 0.9733193386554473 0.9567579706625234 0.9498347753891674 1.0 14.113777045237489 -5.998966098624631 24.99993952482087 0.9563502700589998 1.0558087485023528 0.2565378289617509 0.07163612910021513 47.70490119454254 1153425.4319325695 0.020747580460037166 0.03049300020313658 1.002383481882035e-06 5.998966098624631 0.0994584784433531 GAS(ph)PPISAIEEFSIIPEAPMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GASPPISAIEEFSIIPEAPMR 21 0 A0A2R8YF49;A0A2R8YFR7;Q12774;C9J591;A0A5F9ZGZ6;A0A5F9ZH52 A0A2R8YF49;A0A5F9ZH52 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 GAS(0.972)PPIS(0.028)AIEEFSIIPEAPMR 102.5 0.0011733 0.0 5017.0 4962.1 4713.0 5877.6 7199.5 4844.5 5193.2 5635.2 5106.1 4873.7 True False 5866.279009733221 5454.704494623552 4825.375794152031 5548.297127436301 5788.809657043183 4590.445891745155 4701.262500487929 5487.281970987943 5180.767052707855 5757.263229812028 1.018935347502732 0.9474474723299469 0.8381370803345355 0.9637039172894393 1.0054794137373817 0.7973312507191078 0.8165793907327429 0.9531059727430772 0.8998662812360249 1.0 12.491167460380618 -6.742476750150098 24.99985471326075 0.8856458255375319 0.948355428483365 0.14866821416738007 0.07143444073397662 495.5958871891431 653380.0113434702 0.024435458542978707 0.024396214494556968 1.8093527709234536e-07 6.742476750150098 0.06270960294583305 GAS(ph)PPISAIEEFSIIPEAPMR ddPTM_PC-9_Lapatinib_30min_R1 1 GASPPISAIEEFSIIPEAPMR 21 0 A0A2R8YF49;A0A2R8YFR7;Q12774;C9J591;A0A5F9ZGZ6;A0A5F9ZH52 A0A2R8YF49;A0A5F9ZH52 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 GAS(0.976)PPIS(0.024)AIEEFSIIPEAPMR 122.97 1.0991e-06 2657800.0 21481.0 19199.0 20651.0 17089.0 19967.0 17798.0 18155.0 12508.0 19088.0 15356.0 True False 21174.67700086707 19154.545895083047 18953.154495165272 18345.78206723285 18792.58031663238 17036.821029164414 19094.977066902753 13089.167342698962 16938.108434449023 18010.264139416173 1.1757005248204802 1.0635349790990887 1.0523529443238728 1.0186292619152866 1.0434372406290298 0.9459506477686054 1.060227485787543 0.7267615422725979 0.9404697401066597 1.0 14.136531719584942 -6.1459302612586475 0.5497969311237073 0.8998289205135829 1.1487067184093527 0.4242001531692685 0.08468882138862395 1.138676075082924 0.6644379237513289 0.0631523196844514 0.15245929723421253 7.146110686694281e-07 6.1459302612586475 0.2488777978957698 GAS(ph)QAGMTGYGMPR ddPTM_PC-9_AZD4547_30min_R2 1 GASQAGMTGYGMPR 14 0 P37802;P37802-2;C9J5W6;Q9UI15 P37802 TAGLN2;TAGLN3 Transgelin-2;Transgelin-3 1 GAS(0.976)QAGMT(0.018)GY(0.006)GMPR 60.937 0.032237 4313400.0 26655.0 26838.0 34047.0 50834.0 52433.0 39525.0 32750.0 45795.0 32153.0 36123.0 True False 35130.73554155783 35512.858654305375 33595.51453408538 39115.006677470934 45153.58300946044 37053.49550177031 35664.68655484331 38718.43501441044 33852.54193834952 34858.344764985464 1.00781422005 1.0187763903803417 0.9637725130262474 1.12211313936975 1.295345011757883 1.062973464505688 1.0231319586542102 1.110736475740591 0.9711459957890411 1.0 15.089216444823641 -8.269150107407697 24.67121409570747 0.9855729818324631 1.076670066855038 0.14668659745928203 0.08680621708670826 1169.192927156675 3740886.7681989786 0.08581740798875295 0.02379960942279632 5.3808376974543904e-09 8.269150107407697 0.09109708502257485 GAS(ph)QAGMTGYGMPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GASQAGMTGYGMPR 14 0 P37802;P37802-2;C9J5W6;Q9UI15 P37802 TAGLN2;TAGLN3 Transgelin-2;Transgelin-3 1 GAS(0.931)QAGMT(0.06)GY(0.008)GMPR 71.031 0.01556 5180100.0 30319.0 27766.0 31018.0 32230.0 36130.0 35340.0 25480.0 34729.0 24113.0 24619.0 True False 35451.40787245397 30522.42498089872 31757.586756420067 30424.257591069814 29050.58586137514 33486.70818748559 23066.349940774962 33817.40054841715 24465.607007685812 29082.229816103245 1.2190058360939031 1.0495214835279933 1.0919928408940445 1.0461459724186442 0.9989119144258126 1.1514491288746889 0.793142413309821 1.1628200713031975 0.8412562297454529 1.0 14.82785026852171 -1.5228787452820327 0.33160894974053867 0.9719368077608472 3.187880538270938 0.27299295733938467 0.10982183621731477 80.70665710613905 1.1482036392399195 0.09215843867074923 109.78777288669134 0.029999999999882905 1.5228787452820327 2.215943730510091 GAS(ph)T(ph)LRTLATGHLGFMITS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GASTLRTLATGHLGFMITSK 20 1 Q5SZK8;Q5SZK8-2 Q5SZK8 FREM2 FRAS1-related extracellular matrix protein 2 3 GAS(0.666)T(0.666)LRT(0.666)LAT(0.001)GHLGFMIT(0.032)S(0.968)K 67.449 0.008374600000000001 6379300.0 6848.2 6302.0 10901.0 11044.0 13322.0 10428.0 12021.0 11510.0 10593.0 7868.9 True False 8007.465001884603 6927.620911532944 11160.921182272721 10425.24048513109 10711.649732777185 9881.137322555167 10882.283855496693 11207.874695853074 10747.90258501289 9295.469279821871 0.8614374122312252 0.7452685499774679 1.2006839941368295 1.1215399859113802 1.1523516898742794 1.0630057531365988 1.1707083879153253 1.2057352198648599 1.156251746035446 1.0 13.182311985802725 -5.2611865661139925 24.99999999736154 1.140148981755724 0.8033529592903349 0.8059090176125001 0.06480344113410513 7.990820208730106 790086.0007192375 0.01598840119891684 0.03731911199867282 5.480414842986647e-06 5.2611865661139925 -0.3367960224653891 GAS(ph)TVSSSSSTK ddPTM_PC-9_AZD4547_30min_R2 1 GASTVSSSSSTK 12 0 Q5VTQ0-2;Q5VTQ0-3;Q5VTQ0-4;Q5VTQ0 Q5VTQ0-2 TTC39B Tetratricopeptide repeat protein 39B 1 GAS(0.872)T(0.127)VSSSSSTK 71.558 0.027118 4644000.0 76406.0 64237.0 69688.0 124180.0 111500.0 84522.0 94312.0 76504.0 82122.0 70712.0 True False 100701.51865647215 85000.35402699962 68763.8915866697 95552.2195618748 96020.14963009622 79236.8259785105 102705.58529344665 64682.064687028105 86462.80126461413 68236.39440305764 1.475774321568781 1.2456747571526257 1.0077304375213065 1.4003116723528573 1.4071691576041656 1.1612106218636888 1.5051437900834408 0.9479115251161297 1.2671068279765347 1.0 16.058253796512567 -7.773074946786265 24.999995807669908 1.0806319278612107 1.3011977450682528 0.31962786718967806 0.16149799206560642 302.2531540114211 649406.3289485156 0.08600603487301925 0.041855488714095244 1.6862619997636105e-08 7.773074946786265 0.22056581720704216 GASCQGCPNQR ddPTM_PC-9_Lapatinib_30min_R1 1 GASCQGCPNQR 11 0 I3L531;P53384-2;P53384 I3L531 NUBP1 Cytosolic Fe-S cluster assembly factor NUBP1 0 121.5 0.0026718 0.0 0.0 0.0 0.0 0.0 443.38 0.0 0.0 0.0 0.0 0.0 False True 0.0 0.0 0.0 0.0 417.3012601186193 0.0 0.0 0.0 0.0 0.0 0.0 GASPPIS(ph)AIEEFSIIPEAPMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GASPPISAIEEFSIIPEAPMR 21 0 A0A2R8YF49;A0A2R8YFR7;Q12774;C9J591;A0A5F9ZGZ6;A0A5F9ZH52 A0A2R8YF49;A0A5F9ZH52 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 GAS(0.147)PPIS(0.537)AIEEFS(0.316)IIPEAPMR 77.027 0.0011119 2718300.0 5230.9 4072.0 6530.5 8964.2 9863.4 7826.7 7112.4 7622.9 6742.8 5505.1 True False 6116.38805501565 4476.241249089519 6686.211887059167 8461.96493632852 7930.737575009342 7416.254073882098 6438.661982683189 7422.806952130176 6841.40069387566 6503.131051652381 0.9405297242874318 0.6883209354903206 1.0281527211973172 1.3012139643377507 1.2195260270810968 1.1404128280634451 0.9900864570532051 1.141420477793403 1.0520164270928123 1.0 12.666918782046888 -5.463797874151646 6.128430597563374 1.129018861079793 0.8204392614845402 0.5650453890039957 0.1058809597302612 0.1509805475726005 11.826836895712686 0.02834840954775595 0.05900439456561467 3.437178810941354e-06 5.463797874151646 -0.30857959959525294 GASQAGMT(ph)GYGMPR ddPTM_PC-9_AZD4547_30min_R2 1 GASQAGMTGYGMPR 14 0 P37802;P37802-2;C9J5W6;Q9UI15 P37802 TAGLN2;TAGLN3 Transgelin-2;Transgelin-3 1 GASQAGMT(0.762)GY(0.238)GMPR 85.92399999999999 0.0059524999999999995 1518900.0 2832.5 5267.9 6501.6 8667.8 6021.6 6069.8 4091.7 4846.4 6545.7 6147.0 True False 3733.1760803399975 6970.645655600839 6415.384535930026 6669.572626175049 5185.604780381957 5690.254446467944 4455.8533733267905 4097.500239192898 6891.692338688598 5931.79540100118 0.6293501086888305 1.1751325162739632 1.0815249182140072 1.124376714855901 0.8742049295069619 0.9592802957275856 0.7511812313308586 0.6907689767083528 1.1618223274399189 1.0 12.534253121994167 -6.29179455540231 23.976738188104 0.8856501577526129 1.020557888645905 0.05118340316688064 0.18503839947196504 970.7876974249818 766795.8849513499 0.05672312389589523 0.06432844840236561 5.107465533675706e-07 6.29179455540231 0.1349077308932921 GASQAGMTGY(ph)GMPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GASQAGMTGYGMPR 14 0 P37802;P37802-2;C9J5W6;Q9UI15 P37802 TAGLN2;TAGLN3 Transgelin-2;Transgelin-3 1 GASQAGMT(0.308)GY(0.692)GMPR;GAS(0.001)QAGMT(0.286)GY(0.714)GMPR 52.79 0.034806000000000004 3515300.0 5995.3 7300.6 11552.7 7830.700000000001 13589.3 11656.099999999999 12070.8 9886.3 10436.4 10913.2 True False 7010.185877427465 8025.355320015458 11828.160181858739 7391.971266471935 10926.57421660629 11044.83359660868 10927.366438975909 9626.795100400708 10589.012606270986 12891.676771156326 0.5437761124380628 0.6225222259660812 0.9175036259304076 0.5733909868893577 0.8475681178303561 0.8567414303560767 0.8476295700668403 0.746744994564212 0.8213836566212014 1.0 13.654152301286683 -3.809836246678685 0.42989054948317473 0.8549951580107935 5.8672534433150164e-145 0.46263220403928984 0.1058217755651889 11.761663565869455 0.8920337153198619 0.07377433648538864 6.109393904459357 0.00015494007195566991 3.809836246678685 -0.8549951580107935 GASQAGMTGY(ph)GMPR ddPTM_PC-9_Lapatinib_30min_R1 1 GASQAGMTGYGMPR 14 0 P37802;P37802-2;C9J5W6;Q9UI15 P37802 TAGLN2;TAGLN3 Transgelin-2;Transgelin-3 1 GASQAGMT(0.276)GY(0.724)GMPR 62.693999999999996 0.018747 831900.0 3017.8 2387.5 1959.4 3190.5 4054.9 2860.1 3298.4 2920.2 4000.3 2264.3 True False 2974.76561860326 2381.9718904375623 1798.305695502728 3425.1400131959967 3816.3987542401287 2737.7801902187407 3469.1750128048498 3055.8831527142206 3549.744088973514 2655.6812380099013 1.120151611581393 0.8969344122875794 0.6771541967327117 1.2897406376085663 1.437069592395825 1.0309144603026086 1.3063220702664449 1.1506965177056492 1.3366604538854971 1.0 11.374866274742722 -5.780013817899142 24.99972014304939 1.2324672983036977 0.8979654576507863 0.4563325726476164 0.16153317503905573 196.2988152421656 264202.00359843177 0.04461373201108563 0.06630504024394268 1.659534105385841e-06 5.780013817899142 -0.33450184065291144 GASSAGEAS(ph)EK ddPTM_PC-9_AZD4547_30min_R2 1 GASSAGEASEK 11 0 C9JJX6;E9PDC3;O00192-2;O00192 C9JJX6 ARVCF Armadillo repeat protein deleted in velo-cardio-facial syndrome 1 GASSAGEAS(0.999)EK 80.979 0.015566 553310000.0 10405.0 11659.0 15137.0 18262.0 14917.0 15624.0 12201.0 14542.0 12421.0 12369.0 True False 13713.573562555215 15427.543745828543 14936.273489659898 14051.978045087433 12846.03203616275 14647.028810111551 13286.865363531093 12294.868041916288 13077.548702025922 11935.965074830596 1.1489287608149146 1.2925258786455944 1.251367057126873 1.1772804257545022 1.0762457795097955 1.2271340204402728 1.1131789746561127 1.0300690362979121 1.0956423397721384 1.0 13.543027598870987 -7.274508805496444 0.4343573676902996 1.001115105030532 1.2478603796096528 0.5945133289649451 0.058065574302945296 0.7750417953736263 0.335504521646668 0.06238082022802776 0.0659890946917966 5.314852233193291e-08 7.274508805496444 0.24674527457912077 GATQQILDEAER ddPTM_PC-9_AZD4547_30min_R2 2 GATQQILDEAER 12 0 P78371;P78371-2;F5GWF6;F8VQ14 P78371 CCT2 T-complex protein 1 subunit beta 0 ; 132.86 0.00034402 6172300.0 35445.0 30700.0 35238.0 48752.0 45784.0 38597.0 37635.0 52034.0 37770.0 39562.0 False True 46715.77269819988 40623.17462877914 34770.72109589982 37512.97961089158 39427.681889366206 36183.5234884713 40984.442091344405 43993.34092236776 39766.44509101673 38176.9464217356 1.2236644644686092 1.0640760573153334 0.9107779525316754 0.9826081739616033 1.032761537651909 0.9477846417771808 1.0735390316081013 1.1523535810428427 1.0416350394220153 1.0 15.220414093124294 -7.4874524592568905 24.355732478959247 1.0807858863916762 1.0206902353975895 0.036764575995109294 0.08674897442306868 1129.3140071711384 776410.123126626 0.03771734557726107 0.02541528260804132 3.254974126450616e-08 7.4874524592568905 -0.06009565099408665 GATQQILDEAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GATQQILDEAER 12 0 P78371;P78371-2;F5GWF6;F8VQ14 P78371 CCT2 T-complex protein 1 subunit beta 0 ; 158.42 0.0015169 2036400.0 19659.9 26572.0 26203.0 31689.0 28417.0 25947.0 29002.0 25087.0 24416.0 22960.0 False True 22987.93276927529 29209.89255176983 26827.77889543087 29913.56806712418 22848.892843141344 24586.293642917055 26254.720603703106 24428.492831873657 24773.037809466125 27122.466248739987 0.847560563204433 1.076962997534445 0.9891349352007099 1.1029073754866912 0.8424341884544818 0.9064918144772047 0.9680063886123486 0.9006737295878658 0.913377035195573 1.0 14.727200748401847 -6.268765356512363 24.98778647255611 0.9184060742136159 1.008271111018477 0.22591505883680274 0.0743235123014605 790.990079804945 2697941.8476210865 0.022023216103659003 0.025485595571753453 5.38560681042456e-07 6.268765356512363 0.08986503680486113 GATQQILDEAER ddPTM_PC-9_Lapatinib_30min_R1 1 GATQQILDEAER 12 0 P78371;P78371-2;F5GWF6;F8VQ14 P78371 CCT2 T-complex protein 1 subunit beta 0 123.26 0.0016734000000000002 6621900.0 26226.0 28481.0 27774.0 31262.0 30267.0 37958.0 25547.0 20861.0 30486.0 21138.0 False True 25852.012430740622 28415.053994367416 25490.528930740416 33561.11176697487 28486.75456721153 36334.62482441972 26869.69865756899 21830.278216824656 27052.34564818803 24791.675135385452 1.0427698931018072 1.1461530469076804 1.0281890510237237 1.3537250542248636 1.149045169866398 1.4655978116040604 1.0838194075565935 0.8805487365259171 1.091186678611156 1.0 14.597568134954113 -7.519641703408621 24.967187185335 0.9879573968232638 1.1992904003110996 0.33168789139974875 0.13275169726616096 154.8045856726442 1194033.2616617137 0.06156480168067082 0.036472219395135876 3.022444233940201e-08 7.519641703408621 0.2113330034878358 GATVT(ph)EDSETS(ph)T(ph)ESFQK ddPTM_PC-9_Lapatinib_30min_R1 1 GATVTEDSETSTESFQK 17 0 A0A5F9ZHF7;A0A5F9ZI46;A0A5F9ZHT4;A0A5F9ZI30;A0A5F9ZHE4;D6RHE1;A0A5F9ZH30;A0A5F9ZHD2;A0A5F9ZGY3;A0A5F9ZGY4;A0A5F9ZI40;A0A5F9ZHN5;A0A5F9ZH19;A0A5F9ZI65;A0A5F9ZHT8;A0A5F9ZGZ5;I6L894;A0A5F9ZHR8;A0A5F9ZGX3;A0A5F9ZHS1;Q01484 A0A5F9ZHF7 ANK2 Ankyrin-2 3 GAT(0.092)VT(0.724)EDS(0.336)ET(0.335)S(0.669)T(0.65)ES(0.195)FQK 40.278 0.037258 6064100.0 18558.0 18019.0 20093.0 20775.0 15740.0 16277.0 17384.0 18224.0 18548.0 13568.0 True False 18293.359516879613 17977.27811258407 18441.031101222965 22302.862803368374 14814.204146030635 15580.870653540225 18284.058459434727 19070.753569982862 16458.92892090111 15913.210721776413 1.1495706200789566 1.129707789766341 1.1588504308553746 1.4015312932950765 0.9309374710760385 0.9791154611067019 1.1489861335408529 1.1984227384034771 1.0342934061935039 1.0 13.957937329301192 -6.281062155471983 24.99867042071165 1.0600895120599467 1.200538512928871 0.370139756706214 0.10212868127255072 1099.5083512721403 1400728.1741194099 0.03386311817343804 0.038455202065164514 5.235255051627916e-07 6.281062155471983 0.1404490008689243 GATVYS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 1 GATVYSPSR 9 0 E7EWN3;Q9C0A6;H0Y3R4;Q9C0A6-2;Q9C0A6-3 E7EWN3 SETD5 SET domain-containing protein 5 1 GATVYS(0.967)PS(0.032)R 86.882 0.01132 4873900.0 23931.0 21911.0 30791.0 43609.0 40069.0 34094.0 28825.0 41858.0 28727.0 32700.0 True False 31540.56020427765 28993.30225704168 30382.69122151801 33555.618802333694 34506.11099128547 31962.096790318978 31390.36915857584 35389.80790115062 30245.450572667134 31555.18295310535 0.9995365975583336 0.9188126812678943 0.9628431331445677 1.0633948423687234 1.0935164293791464 1.0128953090786494 0.9947769659654819 1.121521239593 0.9584939062979089 1.0 14.945589367534572 -5.718635221683617 8.341080255847638 1.03982580023843 0.9557885695368328 0.3193402234192776 0.04938965996281172 0.27385879501036625 47.449898739112086 0.01295125634788539 0.02232349882812228 1.9114580814377175e-06 5.718635221683617 -0.08403723070159719 GATVYS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 1 GATVYSPSR 9 0 E7EWN3;Q9C0A6;H0Y3R4;Q9C0A6-2;Q9C0A6-3 E7EWN3 SETD5 SET domain-containing protein 5 1 GAT(0.002)VYS(0.972)PS(0.025)R 88.134 0.010353 4368600.0 29718.0 21238.0 27521.0 22402.0 28040.0 21989.0 22033.0 22452.0 26018.0 17536.0 True False 29294.21587038625 21188.82471585882 25258.329614132155 24049.51781088129 26390.74232876105 21048.581728862588 23173.76093170304 23495.201885055714 23087.57885831385 20567.074234748772 1.424325868425791 1.030230380559408 1.2280954172595608 1.169321291710457 1.2831549119501398 1.0234115698041433 1.1267407637664955 1.1423696738235996 1.1225504704653906 1.0 14.32804895769852 -6.761138290771625 24.99999994433647 1.0946454950213127 1.2129461470635516 0.3270631938231635 0.10161043566046314 11.593003072943304 962606.2402887571 0.03300288537634023 0.03108785432554217 1.7332519969059838e-07 6.761138290771625 0.11830065204223894 GAVAAEGAS(ph)DTEREEPTESQGLAAR ddPTM_PC-9_AZD4547_30min_R2 2 GAVAAEGASDTEREEPTESQGLAAR 25 1 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 GAVAAEGAS(0.615)DT(0.382)EREEPT(0.001)ES(0.001)QGLAAR;GAVAAEGAS(0.526)DT(0.436)EREEPT(0.019)ES(0.019)QGLAAR 78.752 4.9949e-05 125903000.0 18199.4 22993.4 26976.2 36865.8 37156.2 27363.7 24411.0 35903.4 26455.1 29854.2 True False 23986.430628963724 30425.566889556027 26618.477962064037 28366.95938093221 31997.702992697614 25652.643513264822 26583.531709626866 30355.354508055116 27853.462576842907 28809.01354491125 0.8326015950379747 1.0561127628380849 0.923963533863028 0.9846556993945694 1.1106837428784369 0.8904381079648609 0.9227505019630398 1.0536755956858164 0.9668315276891135 1.0 14.81423264128883 -4.745033261242719 24.938027929712455 0.9879219204397022 0.8326011355782924 0.3435349846452017 0.06518162831034885 1131.2347900240616 1719431.8278876774 0.016104306395212483 0.42767623190753346 1.798733150562388e-05 4.745033261242719 -0.15532078486140977 GAVAAEGAS(ph)DTEREEPTESQGLAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GAVAAEGASDTEREEPTESQGLAAR 25 1 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 GAVAAEGAS(0.554)DT(0.433)EREEPT(0.011)ES(0.002)QGLAAR 88.57 3.5357999999999997e-06 9925300.0 5661.0 2536.2 6326.5 7997.3 8189.6 8269.8 6856.9 6219.7 6493.8 7629.3 True False 6619.295490153435 2787.9771748381227 6477.347753384859 7549.237208596428 6584.906669535504 7836.1171298491245 6207.364792343003 6056.439465316884 6588.759539937383 9012.431696494434 0.7344627635544958 0.30934793946039696 0.7187125485682575 0.8376470926856351 0.7306470541237873 0.8694786705453912 0.688755821001948 0.6720094719466954 0.7310745603209635 1.0 13.137700705145681 -10.137451518556269 0.05078252439417697 1.766924961669632 1.3405447231767163e-18 0.32897052738412247 0.13855668548528163 215.86378027284994 2.4710532595065478 54.281567104732844 32.660136312044315 7.286995166307455e-11 10.137451518556269 -1.766924961669632 GAVAAEGASDT(ph)EREEPTESQGLAAR ddPTM_PC-9_AZD4547_30min_R2 1 GAVAAEGASDTEREEPTESQGLAAR 25 1 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 GAVAAEGAS(0.065)DT(0.934)EREEPT(0.001)ES(0.001)QGLAAR 99.569 1.2389e-06 35083000.0 7502.7 11121.0 22756.0 28002.0 21391.0 19267.0 13748.0 21191.0 20252.0 14104.0 True False 9888.402534145414 14715.645766991944 22454.240571493727 21546.571526587355 18421.228885537144 18062.231444215267 14971.545366594999 17916.417870736364 21322.479374722552 13610.22325292349 0.7265422727008813 1.0812200133330663 1.6498069248548537 1.5831166856105119 1.353484696261705 1.3271076534571526 1.1000220267054837 1.3163941206392702 1.5666516983946213 1.0 13.732403111581947 -4.954670215566584 3.923977102339938 1.3713049382968945 0.752267444977322 0.5064979575016699 0.1956243890482693 0.1802920637769737 5.712716688983258 0.051140441469846414 0.24278486295181995 1.1100173944809495e-05 4.954670215566584 -0.6190374933195725 GAVAAEGASDT(ph)EREEPTESQGLAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GAVAAEGASDTEREEPTESQGLAAR 25 1 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 GAVAAEGAS(0.448)DT(0.552)EREEPTESQGLAAR;GAVAAEGAS(0.145)DT(0.849)EREEPT(0.003)ES(0.003)QGLAAR;GAVAAEGAS(0.128)DT(0.781)EREEPT(0.046)ES(0.046)QGLAAR 75.611 0.00011756 87793000.0 11171.599999999999 14857.4 18229.4 19334.2 14225.0 13885.2 18313.1 20454.5 16372.3 13327.0 True False 13062.731230842268 16332.344482864095 18664.058031384488 18250.96745632214 11437.71336501692 13157.0356685024 16578.350592637584 19917.591048334187 16611.713914151467 15743.079603526045 0.8297443422643022 1.0374300895490658 1.1855404724755516 1.1593009700741395 0.7265232504099876 0.8357345576500523 1.053056391134836 1.265164856555331 1.0551756284349139 1.0 13.942430162717077 -10.628516594446268 5.750526885076509 0.9999998506772931 1.0207577136321628 0.00027073449311987297 0.1630588250339419 3.393716768696105e-07 5.2938113035075224e-08 0.17167454164118984 0.04163689258614139 2.3522496119209993e-11 10.628516594446268 0.0207578629548697 GAVAAEGASDT(ph)EREEPTESQGLAAR ddPTM_PC-9_Lapatinib_30min_R1 2 GAVAAEGASDTEREEPTESQGLAAR 25 1 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 GAVAAEGAS(0.155)DT(0.832)EREEPT(0.003)ES(0.01)QGLAAR;GAVAAEGAS(0.331)DT(0.666)EREEPT(0.001)ES(0.001)QGLAAR 87.208 6.240299999999999e-06 130994000.0 36426.4 42262.5 48601.0 38401.0 44648.0 51002.0 37397.3 44658.0 42949.0 35792.0 True False 35906.95285621636 42164.64377785028 44605.21338528534 41225.137641980735 42021.89242134533 48820.763351468864 39333.54920760574 46732.9737120443 38111.63134697985 41978.599510157816 0.8553632868940217 1.004431883623165 1.0625703073894102 0.9820512862037057 1.001031309088266 1.1629917129478178 0.9369905062718437 1.1132570942662354 0.9078823922593641 1.0 15.357366415797111 -4.769043816488063 4.1998091304225005 1.0254018222600705 0.8398392661326278 0.3139589757731056 0.0726603411050803 0.24559675492392094 8.6821171417136 0.016866169540174877 0.13949745747888875 1.7019867842565278e-05 4.769043816488063 -0.18556255612744266 GAVAAEGASDTEREEPT(ph)ESQGLAAR ddPTM_PC-9_AZD4547_30min_R2 1 GAVAAEGASDTEREEPTESQGLAAR 25 1 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 GAVAAEGAS(0.045)DT(0.235)EREEPT(0.518)ES(0.203)QGLAAR 48.832 0.022525 32160000.0 1180.2 1429.2 1580.4 4538.4 3988.4 0.0 1380.7 2574.1 0.0 1445.0 True False 1555.4790503150098 1891.1609504707214 1559.4428633849845 3492.1419975810322 3434.6795047953005 0.0 1503.5796252296846 2176.331991933484 0.0 1394.4109898237698 1.1155097468871757 1.3562435783080944 1.118352390196001 2.504385022110576 2.4631758712898457 0.0 1.0782901427216318 1.5607536141181273 0.0 1.0 10.445440129649807 -6.7605130740167425 24.99998299421778 0.7847610147079965 1.7028877384186958 0.37563534630951423 0.6319530885495568 31.504353172085953 850277.126127143 0.22634291043346222 0.21403439140652383 1.7357490090341747e-07 6.7605130740167425 0.9181267237106993 GAVAAEGASDTEREEPT(ph)ESQGLAAR ddPTM_PC-9_Lapatinib_30min_R1 1 GAVAAEGASDTEREEPTESQGLAAR 25 1 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 GAVAAEGAS(0.016)DT(0.006)EREEPT(0.489)ES(0.489)QGLAAR 62.847 0.001235 54563000.0 2742.4 1925.6 7738.7 5512.8 4024.8 3888.5 4138.5 1551.6 2378.3 2239.6 True False 2703.292873105435 1921.1413915085116 7102.45395824587 5918.229702161695 3788.0691770612543 3722.1979195362273 4352.771280163982 1623.6930003942828 2110.4308093907243 2626.7118759205823 1.0291547001735823 0.7313864185561693 2.7039333942009445 2.2530943558807857 1.4421334946504751 1.4170560363540865 1.6571179047334488 0.618146594332973 0.8034496774226837 1.0 11.359042244563623 -7.755884191087472 24.87277109287527 0.7830985285266338 1.6249705855747618 0.31732298819427374 0.5352149697131914 156.28009051238033 699737.5483100942 0.2840977617323347 0.15804389272538358 1.7543482537608018e-08 7.755884191087472 0.8418720570481281 GAVAAEGASDTEREEPTES(ph)QGLAAR ddPTM_PC-9_Lapatinib_30min_R1 1 GAVAAEGASDTEREEPTESQGLAAR 25 1 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 GAVAAEGAS(0.002)DT(0.002)EREEPT(0.255)ES(0.741)QGLAAR 105.68 3.0256e-07 59869000.0 45510.0 47382.0 46474.0 50939.0 43401.0 54418.0 32589.0 43531.0 54728.0 39364.0 True False 44861.019054488155 47272.2898901414 42653.08711482788 54685.223987522586 40848.23850964903 52090.6689945538 34276.298960798355 45553.609177728504 48563.956328610984 46168.014950767 0.9716904463474851 1.0239186142300463 0.9238666024587067 1.1844828946152057 0.884773550545959 1.128284788724459 0.7424252265849025 0.9866919603605724 1.0518961315620563 1.0 15.494606082864816 GAVDGGLSIPHSTK ddPTM_PC-9_Lapatinib_30min_R1 1 GAVDGGLSIPHSTK 14 0 P46777;A0A2R8Y6J3;Q5T7N0 P46777 RPL5 60S ribosomal protein L5 0 92.939 0.0033149 10821000.0 88597.0 71134.0 114430.0 91567.0 112200.0 106730.0 110550.0 83543.0 109190.0 92527.0 False True 87333.5905333 70969.29359345976 105022.00711257393 98301.1426385575 105600.61659368721 102165.40669978171 116273.73807469575 87424.71276871578 96891.87237832612 108520.16866552207 0.804768289685185 0.6539733071388729 0.967764871765634 0.9058329326923424 0.9730966869316853 0.9414416504887048 1.0714481879683722 0.80560796987124 0.8928466806660026 1.0 16.727603669453813 -5.269682150231658 24.99511922507121 0.9418408757788733 0.7293707956308718 0.572141655733774 0.0744685570721535 379.13599723825195 1149682.2267771221 0.019331678435290902 0.041341253375327514 5.374249809912468e-06 5.269682150231658 -0.2124700801480015 GAVECCPNCR ddPTM_PC-9_Lapatinib_30min_R1 2 GAVECCPNCR 10 0 P31689;P31689-2 P31689 DNAJA1 DnaJ homolog subfamily A member 1 0 ; 116.52 0.0047618 3592000.0 11049.0 11293.2 15205.9 14184.400000000001 13272.3 14861.4 10560.7 9746.3 13814.900000000001 10446.8 False True 10891.439233861558 11267.051289252136 13955.729598471436 15227.568093771288 12491.649408345773 14225.812565615457 11107.48137209804 10199.14867861743 12258.920484653705 12252.515460513998 0.8889145472993885 0.9195704609035016 1.1390093441176516 1.2428115796176669 1.0195171308783433 1.1610524068678612 0.9065470194992985 0.8324126348982033 1.0005227517696549 1.0 13.580790346725015 -7.2840460258251465 24.607036391014116 0.9209049627819264 1.0651606810245347 0.23788935166100333 0.11008328829268571 963.5512005511325 1048807.3686579023 0.04951825525946782 0.033414069465119337 5.199408911208246e-08 7.2840460258251465 0.1442557182426083 GAVEKGEELSCEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GAVEKGEELSCEER 14 1 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 ; 96.06700000000001 0.0039426 18759300.0 49900.0 38552.0 69484.0 74881.0 63855.0 77645.0 63387.0 77091.0 62106.0 48542.0 False True 58347.0844300753 42379.18777870803 71140.76207953754 70685.66033747743 51343.07113695292 73573.15951378946 57382.52447786113 75067.44293466624 63014.18275699146 57342.28034173945 1.0175229182088257 0.7390565482597352 1.2406336416264592 1.2326970590673445 0.8953789565215511 1.2830525586935118 1.0007018230855458 1.3091115750418567 1.0989130948655947 1.0 15.807311657206093 -5.266528716594239 24.998811980918628 1.1393717187796077 0.8782897303746298 0.3324045091406189 0.14387994266474102 398.05192003776176 1955238.5157562 0.035247579894209805 0.07714717556602198 5.41341451902239e-06 5.266528716594239 -0.261081988404978 GAVEKGEELSCEER ddPTM_PC-9_Lapatinib_30min_R1 3 GAVEKGEELSCEER 14 1 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 ;; 94.402 0.0044781000000000005 26899700.0 148164.0 103990.0 151985.0 105985.0 118832.0 114736.0 103518.0 99061.0 125456.0 90606.0 False True 146051.15419004977 103749.21754412654 139489.37997906574 113779.49045559565 111842.53539270083 109829.00874267936 108877.65552253583 103663.73569995993 111325.8241697526 106267.12637509407 1.3743775631471289 0.9763058537775832 1.3126296413314702 1.070693208113909 1.0524659808521317 1.0335181959754216 1.0245657263585664 0.9755014484352867 1.0476036001651414 1.0 16.69733584411337 -1.522878746874878 0.3205140842821677 0.9931731015590028 3.7879906854104033 0.46188808219768496 0.09718428051249998 52.82559063188863 0.7538627314004743 0.0873290756808833 86.58710607340359 0.029999999889853055 1.522878746874878 2.7948175838514002 GAVLVCDMS(ph)S(ph)NFLS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 GAVLVCDMSSNFLSK 15 0 Q9Y617-2;Q9Y617 Q9Y617-2 PSAT1 Phosphoserine aminotransferase 3 GAVLVCDMS(1)S(1)NFLS(1)K 91.845 0.0032760999999999997 1487100.0 4377.1 6002.3 9260.7 7118.1 6207.4 6984.1 8185.7 7252.4 8592.6 5395.9 True False 4314.681751338169 5988.402043130215 8499.320993335767 7641.5888192855155 5842.292936217952 6685.406323732284 8609.51549306229 7589.372980187869 7624.810903910666 6328.574125415195 0.6817778643076411 0.9462482266078123 1.343007259597857 1.2074740167137061 0.9231610186496251 1.0563842962483556 1.360419475610938 1.199223210439991 1.2048228799738407 1.0 12.627664771058958 -4.951406551367105 3.649140425051815 1.1654568352915562 0.6938226256808944 0.5631318523559035 0.13225444209184212 0.1775260818948991 4.684663068377866 0.03554776127545433 0.17851531671579451 1.1183904466029864e-05 4.951406551367105 -0.4716342096106618 GAVRS(ph)PPVDCPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GAVRSPPVDCPR 12 1 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 GAVRS(1)PPVDCPR 58.132 0.032808 5620700.0 9366.3 7487.2 35856.0 12197.0 24495.0 20545.0 17946.0 14421.0 18973.0 12350.0 True False 10951.829597142569 8230.479734819024 36710.94302463725 11513.641633207537 19695.380588828775 19467.58403259455 16246.024962211426 14042.464030312516 19250.444231610447 14588.957237453798 0.7506931043040047 0.5641581917650123 2.5163514038131756 0.7892025074724947 1.3500197627740937 1.3344054489799995 1.113583698806347 0.9625406258825486 1.3195216024205865 1.0 13.8325891481982 -7.428090079837486 8.368845798028838 1.0924610370968733 1.2330698198719963 0.012246687115584076 0.5123379383137676 2.089168325604191 167.2476603675798 0.2171897521446489 0.14590956473993696 3.731727475860894e-08 7.428090079837486 0.140608782775123 GAVRS(ph)PPVDCPR ddPTM_PC-9_Lapatinib_30min_R1 2 GAVRSPPVDCPR 12 1 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 GAVRS(1)PPVDCPR;GAVRS(1)PPVDCPR 64.374 0.020832 21149600.0 30093.0 16015.5 49063.0 32430.0 27652.0 31473.0 20241.4 21930.0 60335.0 22600.0 True False 29663.86830161968 15978.417093739383 45029.22952865686 34815.01038330865 26025.563725923705 30126.97315714637 21289.400650069154 22948.94785940104 53539.43694428345 26506.379887392923 1.1191218275615424 0.6028140078585045 1.698807219995887 1.313457761158381 0.9818603610333864 1.136593276227641 0.8031802434173558 0.8657895931807766 2.019869826499699 1.0 14.694052026927906 -8.231647972240347 24.996109434045334 1.509935747389689 1.0700528586896387 0.193226214986556 0.36338897415581867 981.1820732764907 823251.0644073226 0.24153558271153053 0.09126449029546109 5.8661346540260445e-09 8.231647972240347 -0.4398828887000503 GAVYQAPS(ph)PPPAPVGLGSMAVFR ddPTM_PC-9_AZD4547_30min_R2 2 GAVYQAPSPPPAPVGLGSMAVFR 23 0 Q13057-2;K7EPT0;K7ESK6 Q13057-2 COASY Bifunctional coenzyme A synthase;Phosphopantetheine adenylyltransferase;Dephospho-CoA kinase 1 GAVY(0.024)QAPS(0.925)PPPAPVGLGS(0.051)MAVFR;GAVY(0.064)QAPS(0.934)PPPAPVGLGS(0.003)MAVFR 97.49 0.0025632 2231400.0 11675.3 12248.8 20353.9 23297.0 19321.8 19404.4 15398.3 20592.6 15400.0 19935.0 True False 15387.802538673805 16207.985061660904 20083.99398699799 17926.23658506198 16639.30158854525 18191.03980049468 16768.718869540262 17410.48684087232 16214.012560276879 19237.081717741767 0.7999031643392204 0.8425386604618298 1.0440249868292206 0.9318584205279518 0.8649597601490322 0.9456236692968687 0.8716872504666334 0.9050482342555713 0.8428519875404592 1.0 14.231602337146459 -5.015716766911996 24.73104365465739 0.9207967998533714 0.8105619736464419 0.3461069486174996 0.05844964501331992 610.2965634745003 960340.2738715527 0.014812180031424767 0.04216742877038727 9.644578073606937e-06 5.015716766911996 -0.11023482620692948 GAVYQAPS(ph)PPPAPVGLGSMAVFR ddPTM_PC-9_Lapatinib_30min_R1 1 GAVYQAPSPPPAPVGLGSMAVFR 23 0 Q13057-2;K7EPT0;K7ESK6 Q13057-2 COASY Bifunctional coenzyme A synthase;Phosphopantetheine adenylyltransferase;Dephospho-CoA kinase 1 GAVY(0.213)QAPS(0.724)PPPAPVGLGS(0.063)MAVFR 90.476 1.9939e-05 2277400.0 13153.0 9848.3 13378.0 11620.0 11482.0 12111.0 9075.0 9903.5 11780.0 9233.6 True False 12965.435808035216 9825.496866427746 12278.112480573376 12474.573563183663 10806.651334480546 11593.040762119903 9544.859095683976 10363.652764504246 10453.212351100672 10829.615457001382 1.1972203315541567 0.9072803097616481 1.1337533201731125 1.1518944151538464 0.997879507115279 1.070494220976698 0.8813663914089575 0.9569732928793986 0.9652431697694894 1.0 13.402694395521852 -7.238750929953481 23.018950968017055 0.9473101683698695 1.0711988490284574 0.3626166266611315 0.08129669917540176 319.68844866862395 324345.3283099558 0.030203285309204613 0.02337029000244006 5.770973366988016e-08 7.238750929953481 0.12388868065858794 GCALQCAILS(ph)PAFK ddPTM_PC-9_AZD4547_30min_R2 2 GCALQCAILSPAFK 14 0 A0A087WYC1;P34932;A0A087WTS8;Q92598-2;Q92598-3;Q92598;A0A0A0MSM0;Q92598-4;D6RJ96;E9PDE8;O95757 A0A087WYC1;Q92598-2 HSPA4;HSPH1;HSPA4L Heat shock 70 kDa protein 4;Heat shock protein 105 kDa;Heat shock 70 kDa protein 4L 1 GCALQCAILS(1)PAFK;GCALQCAILS(1)PAFK 103.83 0.001124 29727000.0 81052.0 69690.0 93709.0 118588.0 90127.0 97631.0 74898.0 97320.0 75374.0 90070.0 True False 106824.85001366884 92215.92963777267 92466.3574316272 91249.3687663361 77614.4217552617 91526.11813620084 81563.77690334813 82281.43019112176 79358.11576092917 86916.67671517427 1.2290489472317678 1.0609693458479095 1.063850585712558 1.0498488001946975 0.8929750272160539 1.0530328769487092 0.9384134321038576 0.9466702283240511 0.9130367008967165 1.0 16.407345393251852 -1.522878745280371 0.47019999702528975 0.9507574813065439 7.878942502591188 0.7221162467450466 0.04973737092826448 48.56906843348309 0.5579003257347198 0.028559539419135457 327.05764447305484 0.029999999999997695 1.522878745280371 6.928185021284643 GCALQCAILS(ph)PAFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GCALQCAILSPAFK 14 0 A0A087WYC1;P34932;A0A087WTS8;Q92598-2;Q92598-3;Q92598;A0A0A0MSM0;Q92598-4;D6RJ96;E9PDE8;O95757 A0A087WYC1;Q92598-2 HSPA4;HSPH1;HSPA4L Heat shock 70 kDa protein 4;Heat shock protein 105 kDa;Heat shock 70 kDa protein 4L 1 GCALQCAILS(1)PAFK;GCALQCAILS(1)PAFK 145.69 0.00018774 15277000.0 49405.0 40562.0 40826.0 61216.0 64674.0 62518.0 71305.0 69965.0 61814.0 53419.0 True False 57768.29070677097 44588.72729508079 41799.44667346718 57786.26598494974 52001.59396619362 59239.44602335094 64550.47419650541 68128.49288404519 62717.912809401154 63103.441835428675 0.9154538805890877 0.7065973899072963 0.6623956706272617 0.9157387347532339 0.8240690595262895 0.9387672732312305 1.0229311162590868 1.0796319646354893 0.9938905230077154 1.0 15.945431075462274 -6.763761040701658 1.2216942430914695 1.0364032689289229 0.7743001219268455 0.6458954925324707 0.07700466262154683 0.2749599134423747 0.8651079915224171 0.039248537078941555 0.03530667841614759 1.7228162492970492e-07 6.763761040701658 -0.2621031470020774 GCALQCAILS(ph)PAFK ddPTM_PC-9_Lapatinib_30min_R1 2 GCALQCAILSPAFK 14 0 A0A087WYC1;P34932;A0A087WTS8;Q92598-2;Q92598-3;Q92598;A0A0A0MSM0;Q92598-4;D6RJ96;E9PDE8;O95757 A0A087WYC1;Q92598-2 HSPA4;HSPH1;HSPA4L Heat shock 70 kDa protein 4;Heat shock protein 105 kDa;Heat shock 70 kDa protein 4L 1 GCALQCAILS(1)PAFK;GCALQCAILS(1)PAFK 94.007 0.0035527 17131000.0 49398.0 44619.0 45980.0 40053.0 45100.0 45102.0 34273.0 36026.0 45832.0 37553.0 True False 48693.57546151624 44515.6874468832 42199.70188793271 42998.63123289117 42447.30667001154 43173.09259789712 36047.48824092308 37699.89947937901 40669.91752764395 44043.98601377284 1.1055669540511033 1.01070978073971 0.9581263120630497 0.9762656635901488 0.9637480734994782 0.9802267348009014 0.818442913628453 0.8559602091325251 0.9233932077565868 1.0 15.426657419343607 -1.5228967718184483 0.42592239401621107 0.9039073918656266 4.746802239450132 0.5282870813948127 0.05241854776500957 62.6563691771912 0.7938460107684199 0.03675494122158854 206.02547966864034 0.02999875479670494 1.5228967718184483 3.842894847584506 GCALQCAILSPAFK ddPTM_PC-9_Lapatinib_30min_R1 1 GCALQCAILSPAFK 14 0 A0A087WYC1;P34932;A0A087WTS8;Q92598-2;Q92598-3;Q92598;A0A0A0MSM0;Q92598-4;D6RJ96;E9PDE8;O95757 A0A087WYC1;Q92598-2 HSPA4;HSPH1;HSPA4L Heat shock 70 kDa protein 4;Heat shock protein 105 kDa;Heat shock 70 kDa protein 4L 0 159.09 0.0020268 4320200.0 21662.0 15194.0 18599.0 18842.0 18804.0 22207.0 22936.0 16213.0 17632.0 20722.0 False True 21353.095907675717 15158.819226516584 17069.862014216196 20227.703535069428 17697.985690086407 21257.258377045393 24123.513853290104 16966.315168466437 15646.098486808743 24303.77008967063 0.8785919151181824 0.6237229520599872 0.7023544886754453 0.8322866559565762 0.7281991898700624 0.8746485956135654 0.992583198585427 0.6980939626184708 0.6437724858769343 1.0 14.568892506869558 -5.763644928509775 24.993054401898444 0.8167615568298628 0.7237730930860757 0.09390980330755172 0.12424559812902614 139.77801387211233 1583980.865185355 0.03516979118372643 0.05516266357231669 1.7232769199313776e-06 5.763644928509775 -0.09298846374378711 GCDS(ph)PDPDTSYVLTPHTEEK ddPTM_PC-9_AZD4547_30min_R2 2 GCDSPDPDTSYVLTPHTEEK 20 0 Q02078-3;Q02078-5;Q02078 Q02078-3 MEF2A Myocyte-specific enhancer factor 2A 1 GCDS(1)PDPDTSYVLTPHTEEK;GCDS(0.998)PDPDT(0.002)SYVLTPHTEEK 115.96 1.0547e-05 18210900.0 97169.0 95337.0 133346.0 165485.0 149588.0 139463.0 118341.0 106460.0 99321.0 125368.0 True False 128066.7207592432 126152.82083335222 131577.74491327134 127334.98996776335 128820.28827683278 130742.3565632736 128873.11974310597 90009.05320742747 104570.90529215966 120978.90447904918 1.0585872083295438 1.042767095441826 1.0876089966251732 1.0525387919165272 1.0648161250223716 1.0807037567935263 1.0652528248462019 0.744006185169374 0.8643730553062579 1.0 16.884395976012847 -7.741718863298366 24.995955667797002 0.853142244437804 1.0648177159552668 0.6931438312128049 0.059204600213127366 107.93895755847815 136814.0187559075 0.02603299803282418 0.015003610106477088 1.8125130272529023e-08 7.741718863298366 0.2116754715174628 GCDS(ph)PDPDTSYVLTPHTEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GCDSPDPDTSYVLTPHTEEK 20 0 Q02078-3;Q02078-5;Q02078 Q02078-3 MEF2A Myocyte-specific enhancer factor 2A 1 GCDS(0.997)PDPDT(0.003)SYVLTPHTEEK 118.08 8.6632e-06 6654700.0 10917.0 11427.0 14963.0 17050.0 18643.0 15821.0 18162.0 14244.0 11337.0 13271.0 True False 12765.03247942149 12561.397041587894 15319.774667493504 16094.74377684581 14990.037979895287 14991.318908721252 16441.563878506855 13870.110092765508 11502.782177503179 15676.92724682181 0.8142560259702265 0.8012665265212908 0.9772179475157856 1.0266516852088283 0.9561847002214177 0.9562664081228321 1.0487746494989993 0.8847467283856536 0.7337395904439847 1.0 13.936355191541294 -5.256461243902037 24.41223395121636 0.9508346192840442 0.8077612514603947 0.3092202406907797 0.08372224744575672 367.0568636993943 1799984.7929589292 0.022554753925186254 0.0557913231454644 5.540369835572099e-06 5.256461243902037 -0.14307336782364954 GCDS(ph)PDPDTSYVLTPHTEEK ddPTM_PC-9_Lapatinib_30min_R1 2 GCDSPDPDTSYVLTPHTEEK 20 0 Q02078-3;Q02078-5;Q02078 Q02078-3 MEF2A Myocyte-specific enhancer factor 2A 1 GCDS(0.989)PDPDT(0.008)S(0.002)YVLTPHTEEK;GCDS(1)PDPDTSYVLTPHTEEK 105.72 7.8963e-05 19868800.0 96516.0 105045.0 112019.0 101663.0 109223.0 107153.0 92067.0 100258.0 105930.0 81036.0 True False 95139.66414113327 104801.7747564457 102809.23022584482 109139.63615782617 102798.71788068005 102570.31597584292 96833.77877270931 104916.3526898236 93999.04790764811 95042.96462631733 1.0010174294877703 1.102677880140811 1.0817132086531842 1.148318937513503 1.0816026024109853 1.0791994586776734 1.0188421536873662 1.1038834184342388 0.9890163704091763 1.0 16.53629221763446 -8.269735883854521 24.778058519732763 0.994508165481317 1.0788039836862016 0.40910919388912315 0.03969157661654063 592.0204730175988 1768081.770315782 0.036079872216981425 0.009950771267799046 5.3735849153293565e-09 8.269735883854521 0.08429581820488452 GCDVVVIPAGVPR ddPTM_PC-9_Lapatinib_30min_R1 2 GCDVVVIPAGVPR 13 0 P40926;P40926-2 P40926 MDH2 Malate dehydrogenase, mitochondrial 0 ; 150.61 0.00059292 6578200.0 36850.0 35905.0 49484.0 32695.0 35315.0 34382.0 28489.0 25978.0 41228.0 28201.0 False True 36324.51224253762 35821.864178496646 45415.61653376389 35099.4993673227 33237.84113196136 32911.562008356595 29964.02102225243 27185.03271735157 36584.468489913284 33075.50527452952 1.098230002566584 1.083033014346179 1.3730891231081852 1.061193142054637 1.0049080386250924 0.9950433632135872 0.9059278391531285 0.8219083122604923 1.1060894818161982 1.0 15.013475575403064 -6.11563104564618 3.2278686130386323 0.9601675828405402 1.1785844136431052 0.45321251170531396 0.10223573172739121 0.22527492334597626 4.421014752790045 0.03175631105960842 0.04319172296839526 7.66247294942673e-07 6.11563104564618 0.21841683080256502 GCIS(ph)MPEQK ddPTM_PC-9_AZD4547_30min_R2 2 GCISMPEQK 9 0 B4DZ85;B4DF87;Q13772-2;Q13772;Q13772-3;Q13772-4 B4DZ85 NCOA4 Nuclear receptor coactivator 4 1 GCIS(1)MPEQK;GCIS(1)MPEQK 93.111 0.0057319 3829000.0 43981.0 57223.0 87000.0 117949.0 98792.0 93076.0 79663.0 91106.0 73061.0 85894.0 True False 57966.04313837013 75719.21569324528 85846.32315520986 90757.68034388447 85076.43607404928 87255.9430062689 86752.85267232024 77027.66110760717 76922.85530301231 82886.87720409886 0.6993392089755752 0.913524773128995 1.0357046380674195 1.0949583746580862 1.0264162306966749 1.0527111884238534 1.046641586685693 0.9293106907374001 0.9280462468576194 1.0 16.33885608933828 -4.821050514664257 2.493778623239369 1.0170171541208146 0.6451278945553427 0.7858670445836177 0.04995095637236602 0.22952512731891628 1.9498550766642748 0.014658596210772269 0.17843761935472735 1.5099045204431565e-05 4.821050514664257 -0.3718892595654719 GCITIIGGGDTATCCAK ddPTM_PC-9_Lapatinib_30min_R1 2 GCITIIGGGDTATCCAK 17 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 ; 289.38 1.5703999999999998e-96 18046900.0 96192.0 83168.0 98839.0 90637.0 85048.0 82140.0 89556.0 78410.0 76814.0 89511.0 False True 94820.2844405476 82975.42960582656 90712.83894957327 97302.74733616864 80045.64385080132 78627.06367769212 94192.77147912669 82053.21484977823 68162.39843272044 104982.85708408995 0.9031977893742952 0.7903712273649047 0.8640728731254992 0.9268441537862736 0.7624639495826044 0.7489514560907103 0.8972204995686054 0.7815867954903783 0.6492717032660219 1.0 16.679794240243112 -6.276455959338882 24.63713639565268 0.7973120997672175 0.8648501651313657 0.09615517058059786 0.09361729510525202 1552.518585751663 2547152.426029249 0.028296125809732398 0.03221526346211497 5.291076499042522e-07 6.276455959338882 0.06753806536414819 GCLAGGGS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 GCLAGGGSPK 10 0 Q9H257-2;Q9H257 Q9H257-2 CARD9 Caspase recruitment domain-containing protein 9 1 GCLAGGGS(1)PK 91.63600000000001 0.0079446 6251400.0 37646.0 37398.0 37880.0 41219.0 45464.0 42673.0 41709.0 43432.0 39748.0 46858.0 True False 49616.64491455584 49486.17214225025 37377.68644964766 31716.596377201753 39152.10836576411 40004.650564125106 45421.02019896061 36720.58236807235 41848.99813284972 45217.51568246519 1.0972881673328325 1.0944027197283728 0.8266196381094479 0.7014227981901506 0.8658615533127757 0.8847158000685656 1.0045005682736863 0.812087568585997 0.9255041437200907 1.0 15.4645941100059 -5.2543521070950865 23.945748932183285 0.8689544449179897 1.0958455097531965 0.511922245733905 0.08491092005644493 239.78687697613185 810156.6208345735 0.022517411360311223 0.05682711754168056 5.567341900142828e-06 5.2543521070950865 0.22689106483520682 GCLAGGGS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GCLAGGGSPK 10 0 Q9H257-2;Q9H257 Q9H257-2 CARD9 Caspase recruitment domain-containing protein 9 1 GCLAGGGS(1)PK 72.096 0.031454 7375200.0 44076.0 56849.0 48260.0 52921.0 54943.0 53463.0 55341.0 53721.0 50078.0 41629.0 True False 51537.19625931861 62492.59301804767 49410.701427069216 49956.007942196935 44177.31356162561 50659.30616376741 50098.69984585659 52310.880672104475 50810.29601173181 49176.00816501729 1.048015041936263 1.2707943436226998 1.004772515517412 1.01586138863818 0.8983509481571211 1.0301630419812178 1.0187630455433283 1.0637480068851393 1.033233438574974 1.0 15.585667009272605 -5.29324889333952 24.477808692610825 1.007912960385196 1.1594046909846933 0.4698316409828853 0.06428551316693361 364.77821876158066 280700.6595069122 0.01638304283723019 0.03410924581598324 5.090390581328237e-06 5.29324889333952 0.1514917305994974 GCLAGGGS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 GCLAGGGSPK 10 0 Q9H257-2;Q9H257 Q9H257-2 CARD9 Caspase recruitment domain-containing protein 9 1 GCLAGGGS(1)PK;GCLAGGGS(1)PK 99.539 0.0043347 15948800.0 85482.0 107330.0 86073.0 98911.0 107617.0 92568.0 108993.0 105164.0 84247.0 89051.0 True False 84263.01100452093 107081.48397933575 78996.41019138832 106185.24489742356 101287.17964316251 88609.0824265474 114636.12423315512 110050.30336005682 74758.2156997605 104443.34669700124 0.8067819891771074 1.0252590266949984 0.756356557785949 1.0166779240182309 0.969781061660203 0.8483937486569599 1.0975914489385712 1.0536841918645312 0.715777673389194 1.0 16.672361066478352 -5.8014716692232415 24.999642567081654 0.9614653271737662 0.8790439931198911 0.10888392877475783 0.12101144149953937 374.8122696021813 234063.73313702983 0.03329823473171947 0.04938997940702016 1.5795316435833192e-06 5.8014716692232415 -0.08242133405387508 GCLTTPNS(ph)PSMHSR ddPTM_PC-9_AZD4547_30min_R2 2 GCLTTPNSPSMHSR 14 0 O75128-3;O75128;O75128-7;A0A0J9YWK3;A0A3B3IU00;O75128-5;O75128-4 O75128-3 COBL Protein cordon-bleu 1 GCLTT(0.003)PNS(0.972)PS(0.02)MHS(0.005)R;GCLTTPNS(0.978)PS(0.009)MHS(0.013)R 89.87700000000001 0.0035720999999999995 12116800.0 20032.0 21535.3 66685.0 109184.0 79290.0 80221.0 57833.0 102924.0 67429.0 89994.0 True False 26401.759308515724 28496.164579255626 65800.71332879506 84013.31567598436 68281.95214502554 75204.7681884255 62980.02496263368 87019.46075823072 70993.15928096815 86843.3374520417 0.30401594507000396 0.3281329969036753 0.7576944329797642 0.9674123328387719 0.786265868498358 0.8659820130698745 0.7252142399227082 1.0020280577803253 0.8174853864888986 1.0 16.406127550378002 -5.311835992163356 3.4120694934624596 0.8695379856333465 0.30039366836727055 0.8668465036310513 0.08710851067416937 0.07232615315855544 1.6957211918220751 0.022261032112388095 0.05672997095010891 4.877126361057875e-06 5.311835992163356 -0.569144317266076 down GCLTTPNS(ph)PSMHSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GCLTTPNSPSMHSR 14 0 O75128-3;O75128;O75128-7;A0A0J9YWK3;A0A3B3IU00;O75128-5;O75128-4 O75128-3 COBL Protein cordon-bleu 1 GCLTTPNS(0.977)PS(0.022)MHS(0.001)R 79.92 0.008464200000000002 4197600.0 10159.0 12647.0 33265.0 23987.0 36732.0 33481.0 26532.0 25400.0 25368.0 19382.0 True False 11878.718050603908 13902.510578888789 34058.16375821503 22643.08615690326 29534.628282868296 31725.197420068045 24018.696884954516 24733.276913524584 25738.959008459053 22895.80317217242 0.518816394484091 0.6072078133422248 1.4875286751071197 0.9889622996245744 1.2899581666025464 1.3856337417604498 1.0490436480580363 1.0802537359154727 1.1241780345029437 1.0 14.482795554396509 -5.167157886589659 6.863128329155481 1.1782487601018545 0.5477473482237069 0.7061084824453758 0.15827854024872762 0.1271721300123471 7.8904112404419955 0.03935651775395488 0.10635828295001047 6.805219118082514e-06 5.167157886589659 -0.6305014118781477 GCLTTPNS(ph)PSMHSR ddPTM_PC-9_Lapatinib_30min_R1 2 GCLTTPNSPSMHSR 14 0 O75128-3;O75128;O75128-7;A0A0J9YWK3;A0A3B3IU00;O75128-5;O75128-4 O75128-3 COBL Protein cordon-bleu 1 GCLTTPNS(0.973)PS(0.023)MHS(0.003)R;GCLTTPNS(0.981)PS(0.018)MHS(0.001)R 96.666 0.0020061 7969500.0 34229.0 22358.0 46521.0 30483.0 41939.0 40726.0 25785.0 31436.0 48756.0 26178.0 True False 33740.888183170166 22306.231424671423 42696.222956253114 32724.821508307028 39472.23047524641 38984.2439169429 27120.02113302603 32896.63132276018 43264.585856558944 30702.832420007577 1.0989503418317468 0.7265203131596261 1.3906281470119355 1.0658567607261478 1.2856217933015273 1.2697279320568065 0.8833068155416568 1.0714526553362225 1.4091398886170994 1.0 14.906084133835648 -5.256442193122953 24.987944981366688 1.1679702824166702 0.9127353526073022 0.24537490108172222 0.18173553724416514 569.7263058552235 2848837.7537399554 0.04547232270510058 0.11266417421234715 5.540612874987076e-06 5.256442193122953 -0.255234929809368 GCLTTPNSPS(ph)MHSR ddPTM_PC-9_AZD4547_30min_R2 1 GCLTTPNSPSMHSR 14 0 O75128-3;O75128;O75128-7;A0A0J9YWK3;A0A3B3IU00;O75128-5;O75128-4 O75128-3 COBL Protein cordon-bleu 1 GCLT(0.001)T(0.003)PNS(0.024)PS(0.914)MHS(0.058)R 69.346 0.026347000000000002 2278500.0 2121.4 2004.1 9874.5 13913.0 14769.0 12934.0 6964.4 16956.0 10162.0 12855.0 True False 2795.96107213884 2651.886132688479 9743.557678116314 10705.57280370723 12718.5792814968 12125.234935354774 7584.218108169494 14335.839810117775 10699.142573865829 12404.950362757472 0.2253907504969114 0.2137764404644499 0.7854572080649936 0.8630081129423809 1.025282561362028 0.9774513061944634 0.6113864131967082 1.1556547499905585 0.8624897529608121 1.0 13.598628341982783 -5.329604375635491 2.895014695994092 0.9247975303383783 0.19484355736189415 0.8112987280837726 0.1344796435551322 0.10360412319422507 1.6796572222484667 0.03612854690897098 0.097633209270324 4.6816142284643356e-06 5.329604375635491 -0.7299539729764841 down GCLTTPNSPS(ph)MHSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GCLTTPNSPSMHSR 14 0 O75128-3;O75128;O75128-7;A0A0J9YWK3;A0A3B3IU00;O75128-5;O75128-4 O75128-3 COBL Protein cordon-bleu 1 GCLTTPNS(0.012)PS(0.979)MHS(0.009)R 87.789 0.024771 0.0 3375.3 3181.6 9734.5 7810.4 10089.0 8380.2 7037.2 6826.9 8964.6 4270.6 True False 3946.671624786237 3497.448221538117 9966.60739829683 7372.8086096584475 8112.132874492495 7940.727559501041 6370.585471084047 6647.701108698466 9095.690315643022 5044.825973949001 0.7823206677824908 0.693274305119464 1.9756097533915813 1.4614594532558558 1.6080104480080726 1.5740339905689904 1.2627958831446595 1.3177265465700023 1.8029740495732254 1.0 12.300588787719963 -5.23992745730061 24.89641483617981 1.5082805961503287 0.7377972453302082 0.5773792950519816 0.26088121132291986 507.4888243218582 587330.3681471113 0.06353820176906093 0.16776046988920426 5.7553606439999635e-06 5.23992745730061 -0.7704833508201205 GCMTAAEIS(ph)KYLT(ph)LS(ph)SIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GCMTAAEISKYLTLSSIK 18 1 Q96KC2 Q96KC2 ARL5B ADP-ribosylation factor-like protein 5B 3 GCMT(0.003)AAEIS(0.958)KY(0.079)LT(0.653)LS(0.653)S(0.653)IK 48.898999999999994 0.028324000000000002 4996900.0 4568.1 2196.7 1938.0 3792.9 4450.2 5289.7 4930.5 4346.0 1959.5 2482.4 True False 5341.389105912366 2414.7738585154566 1984.2092699059276 3580.396109747712 3578.215256028001 5012.298820015348 4463.447346271229 4231.92210496763 1988.1539804902052 2932.439469332414 1.8214831582281092 0.8234692936612237 0.6766411687800818 1.2209616420702485 1.2202179425864166 1.709259090403808 1.5220935991859903 1.443140480553909 0.6779863663964458 1.0 11.517885613480155 -6.115066370396074 3.739376791694276 1.3188949997246817 1.0650690167255146 0.010368049544148938 0.38989983226115155 0.6945050728056757 17.35462537392736 0.12043415713015734 0.16156362809821484 7.672442274654679e-07 6.115066370396074 -0.25382598299916714 GCNGDQREMARVVVT(ph)VIS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 GCNGDQREMARVVVTVISR 19 2 D6R9H2;O15195-2;O15195 D6R9H2 VILL Villin-like protein 2 GCNGDQREMARVVVT(1)VIS(1)R 66.977 0.040336000000000004 0.0 2380.4 4597.6 3672.9 4886.6 4367.7 4319.5 2875.1 5564.6 3139.2 4130.2 True False 3137.317684604176 6083.684289031762 3624.194946169774 3760.0698672174058 3761.320246989882 4049.4009821605764 3130.9783301932844 4704.718931787056 3305.13170319618 3985.602955135038 0.7871626250582904 1.5264150387066435 0.9093216225917268 0.9434130568306971 0.9437267809488673 1.0160071205646166 0.785572061602208 1.1804284031166505 0.8292676767859826 1.0 11.96058228104363 GCS(ph)PPAPAGSPR ddPTM_PC-9_AZD4547_30min_R2 2 GCSPPAPAGSPR 12 0 Q9C073;D6RFX7 Q9C073 FAM117A Protein FAM117A 1 GCS(0.964)PPAPAGS(0.036)PR;GCS(0.999)PPAPAGS(0.001)PR 120.03 0.0005114 3294600.0 26170.0 26448.0 45120.0 56674.0 50798.0 46352.0 27922.0 45299.0 29506.6 33921.0 True False 34491.515630184535 34996.79878117104 44521.679319115705 43608.6849045715 43745.57453730612 43453.60211253783 30407.003907918643 38299.08041746432 31066.258637082192 32733.436114748834 1.053708981521911 1.0691452818606597 1.3601284986715891 1.3322366998594004 1.336418651068395 1.3274989512316664 0.9289279561523954 1.1700293327961298 0.9490680577553099 1.0 14.998477433368434 -7.258138128713725 24.999012615767192 1.0261754460311554 1.2516063803391506 0.4826316002234663 0.11851931320729285 290.8204693327377 2202273.859272907 0.050497933906277624 0.03744646799753072 5.519018772507984e-08 7.258138128713725 0.2254309343079952 GCS(ph)PPAPAGSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GCSPPAPAGSPR 12 0 Q9C073;D6RFX7 Q9C073 FAM117A Protein FAM117A 1 GCS(0.765)PPAPAGS(0.235)PR;GCS(0.994)PPAPAGS(0.006)PR 98.156 0.0037464 4248400.0 26309.0 35780.0 37490.0 36742.0 44778.0 33020.0 33682.0 26086.0 29629.0 26959.0 True False 30762.59407356416 39332.00193821781 38383.90378161675 34683.464859171196 36004.07234156256 31288.373071612146 30491.397123437266 25401.27014040166 30062.268072439034 31846.45329267341 0.9659660933307571 1.2350512497184898 1.205280331497616 1.0890840666125439 1.1305520275893848 0.9824759066282067 0.9574503271437171 0.7976169247784171 0.9439753870285817 1.0 14.95884508948822 -6.922329488524853 1.8930736656046152 0.9048665664401273 1.13866639451414 0.5591114114849551 0.08406540574416875 0.23062131011176942 1.6839166661530447 0.03621534321093034 0.0295221457711637 1.195832938074926e-07 6.922329488524853 0.23379982807401267 GCS(ph)PPAPAGSPR ddPTM_PC-9_Lapatinib_30min_R1 1 GCSPPAPAGSPR 12 0 Q9C073;D6RFX7 Q9C073 FAM117A Protein FAM117A 1 GCS(0.97)PPAPAGS(0.03)PR 86.11399999999999 0.0092979 1840900.0 10435.0 12622.0 13787.0 9043.8 11021.0 12292.0 9536.7 11108.0 10408.0 10351.0 True False 10286.194986455368 12592.77453449337 12653.486079359036 9708.911221232394 10372.76644811967 11766.299814051512 10030.463662568518 11624.118231747683 9235.74143890117 12140.156558159475 0.8472868481701706 1.0372827132966163 1.0422835997822901 0.7997352566847232 0.8544178486024605 0.9692049486909877 0.8262219366377924 0.9574932725175641 0.7607596652197842 1.0 13.567499406103828 -5.754766878069219 24.999994376028166 0.8796181985944078 0.981784208424239 0.1939306568048217 0.08798112123919123 235.45583861518412 882175.9519051741 0.022962892177343968 0.03863571372080931 1.7588674909212136e-06 5.754766878069219 0.10216600982983115 GCSFLPDPYQK ddPTM_PC-9_Lapatinib_30min_R1 1 GCSFLPDPYQK 11 0 C9JIZ6;P07602;P07602-2;P07602-3;Q5BJH1 C9JIZ6 PSAP Prosaposin;Saposin-A;Saposin-B-Val;Saposin-B;Saposin-C;Saposin-D 0 102.06 0.016012000000000002 5907900.0 32262.0 34847.0 35005.0 33935.0 32090.0 34278.0 32402.0 30062.0 30870.0 28862.0 False True 31801.937963873785 34766.313912493315 32127.024023207592 36430.693103841455 30202.529291367424 32812.009845920744 34079.61701579639 31458.790266726588 27393.095524488755 33850.758243802404 0.9394749073219437 1.0270468289689947 0.9490784162593935 1.0762149799262295 0.8922260787732009 0.9693138809358328 1.0067608167103876 0.9293378316713555 0.8092313716341655 1.0 15.046900529518755 -7.976570994985499 7.520223683097783 0.8929432861683683 0.9798525951345682 0.18944874547675272 0.06409241898630581 0.22005691153859058 52.04073107119085 0.03392544937044285 0.01579702786545888 1.0554289560356705e-08 7.976570994985499 0.08690930896619997 GCT(ph)PSGEGADSEPR ddPTM_PC-9_AZD4547_30min_R2 1 GCTPSGEGADSEPR 14 0 Q92917 Q92917 GPKOW G patch domain and KOW motifs-containing protein 1 GCT(0.982)PS(0.018)GEGADSEPR 134.04 9.1188e-05 0.0 4481.9 5675.5 7578.9 11636.0 8832.7 9614.5 7268.0 8057.1 7850.3 8760.8 True False 5907.050970688733 7509.994384548409 7478.398834034707 8953.499974407918 7606.432068500014 9013.30379511121 7914.837920018361 6812.060328739082 8265.250831294908 8454.087058579988 0.6987213320323823 0.8883270697959721 0.8845897590379008 1.0590735477843323 0.8997342960621992 1.066147501516876 0.9362143854416135 0.8057712537778488 0.9776633211869482 1.0 13.045433253706321 -4.520330914241349 1.4369566445409319 0.9537014552719619 0.4434290666134679 0.5195485981381134 0.07444218514199889 1.912005006171784 2.248031782640817 0.021499572051531173 1.6788018059854923 3.0176515198671167e-05 4.520330914241349 -0.510272388658494 GCT(ph)PSGEGADSEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GCTPSGEGADSEPR 14 0 Q92917 Q92917 GPKOW G patch domain and KOW motifs-containing protein 1 GCT(0.986)PS(0.013)GEGADS(0.001)EPR 116.19 0.0012372 0.0 5676.6 5972.0 6038.8 6755.6 7237.4 7257.5 5985.2 5717.9 5759.0 3974.9 True False 6637.536262039392 6564.860692426967 6182.787894276532 6377.10563395071 5819.283424110612 6876.903923901433 5418.238526904485 5567.811183615838 5843.214480042407 4695.517904708914 1.4135898098446007 1.3981121626313844 1.3167424807551271 1.3581261456921314 1.2393272780995523 1.4645677140331868 1.153917126260085 1.1857714732664828 1.2444238524109388 1.0 12.197068577226474 -9.828126657285829 0.1201790352171184 0.6371697053039659 1.5811121297224453 0.6964124063357066 0.07378854029905793 15.544598268766658 0.5194055298429644 2.9829728058758818 1.113440139437481 1.4855023484231356e-10 9.828126657285829 0.9439424244184794 GCT(ph)PSGEGADSEPR ddPTM_PC-9_Lapatinib_30min_R1 1 GCTPSGEGADSEPR 14 0 Q92917 Q92917 GPKOW G patch domain and KOW motifs-containing protein 1 GCT(0.963)PS(0.008)GEGADS(0.029)EPR 89.44 0.015648 0.0 6395.6 6169.4 7075.5 6093.9 6866.2 8459.2 7537.2 5956.0 7999.7 6271.2 True False 6304.3975711906 6155.115133346803 6493.7797022198365 6542.06573465447 6462.34361546859 8097.419735358335 7927.439336197164 6232.737503446994 7098.689545424452 7355.16856415126 0.8571384212617412 0.836842157954957 0.8828865913243931 0.8894515030614235 0.8786125782304628 1.1009155894570208 1.0778052558625406 0.8473956033890315 0.9651294166150216 1.0 12.844542689891808 -6.617949727630121 10.871564591733145 0.9936247673419142 0.8679233044010863 0.49506480685995513 0.06527241501431763 0.3830252920286657 40.90212384235301 0.023440774480527397 0.023435106156838387 2.4101844068326323e-07 6.617949727630121 -0.12570146294082785 GCTATLGNFAK ddPTM_PC-9_Lapatinib_30min_R1 1 GCTATLGNFAK 11 0 H0YEN5;P15880;E9PQD7 H0YEN5 RPS2 40S ribosomal protein S2 0 146.11 0.0010193 9269500.0 40352.0 35934.0 38998.0 37528.0 39576.0 42449.0 36884.0 40432.0 34006.0 38845.0 False True 39776.57308034948 35850.79703077837 35791.73497663335 40287.93430973809 37248.217489409704 40633.55522345206 38793.67304520194 42310.61832427282 30175.886180944777 45559.306492291034 0.8730724004124155 0.7869039235012188 0.7856075461264884 0.8842964788446703 0.8175764812335845 0.8918826547618224 0.8514983223409275 0.9286932041301393 0.662342965779138 1.0 15.475458165933764 -5.761994351713087 24.999669538225216 0.8582717066448119 0.812365555536744 0.05914836823029712 0.08484853841084034 46.30991593386354 2086285.2866418208 0.02211796118928203 0.03519673458928444 1.7298388567669873e-06 5.761994351713087 -0.04590615110806784 GCTWGPNS(ph)IQMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GCTWGPNSIQMK 12 0 Q5TCX8;Q5TCX8-3 Q5TCX8 MLK4 Mitogen-activated protein kinase kinase kinase MLK4 1 GCT(0.469)WGPNS(0.531)IQMK 66.56 0.034315 8069300.0 38432.0 39817.0 34790.0 42192.0 46200.0 40621.0 40995.0 38009.0 35366.0 29883.0 True False 44937.7785333999 43769.76861861429 35619.52554180972 39828.11902830961 37147.44164947496 38490.76325081638 37111.65682190223 37011.304023864395 35883.160844101374 35300.55134630215 1.2730050047251538 1.2399174219469895 1.00903595505856 1.1282577044644866 1.0523190214525155 1.090372863392923 1.0513053027935158 1.0484624917265337 1.016504260573263 1.0 15.10740309614404 -5.207016986466507 6.258506198753391 1.05576321693971 1.2603450784580956 0.8313627585899683 0.037213724882573844 0.08208062229430038 7.20865982356373 0.009184319313881018 0.024710934222365994 6.208447507881863e-06 5.207016986466507 0.20458186151838564 GDAAS(ph)SPAPAASVGSSQGGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GDAASSPAPAASVGSSQGGAR 21 0 F8WCC1;E7EXA6;A0A0D9SF58;Q8WVB6;Q8WVB6-2 F8WCC1 CHTF18 Chromosome transmission fidelity protein 18 homolog 1 GDAAS(0.5)S(0.5)PAPAASVGSSQGGAR;GDAAS(0.906)S(0.094)PAPAASVGSSQGGAR;GDAAS(0.58)S(0.42)PAPAASVGSSQGGAR 275.31 6.588899999999997e-144 45826000.0 45334.3 40371.8 46363.8 51421.1 58783.2 46853.9 50332.0 48642.1 45703.7 33735.9 True False 53008.50159676075 44379.64549606886 47469.28882769066 48540.142476455476 47265.053938732 44396.79900242304 45564.18858787617 47365.296415565106 46372.03014959442 39851.95161676256 1.3301356507334579 1.1136128519588449 1.1911408827397072 1.218011678405192 1.1860160424076027 1.1140432827322018 1.143336442492089 1.188531414246781 1.1636075090006226 1.0 15.282362756685696 -14.522878745279158 0.1366678584466665 0.40498141854241765 1.245013796936668 0.5400590089442503 0.05454768726544564 115.67756386300955 0.9747527576318564 18.8718359087949 0.35527985113702015 3.0000000000081488e-15 14.522878745279158 0.8400323783942503 GDAAS(ph)SPAPAASVGSSQGGAR ddPTM_PC-9_Lapatinib_30min_R1 3 GDAASSPAPAASVGSSQGGAR 21 0 F8WCC1;E7EXA6;A0A0D9SF58;Q8WVB6;Q8WVB6-2 F8WCC1 CHTF18 Chromosome transmission fidelity protein 18 homolog 1 GDAAS(0.915)S(0.085)PAPAASVGSSQGGAR;GDAAS(0.5)S(0.5)PAPAASVGSSQGGAR;GDAAS(0.583)S(0.417)PAPAASVGSSQGGAR 289.81 1.7446999999999995e-116 55065200.0 74286.4 65420.4 78858.9 62044.0 67675.8 65138.5 62699.3 57681.5 70060.8 54859.3 True False 73227.06231354283 65268.92308321739 72375.42564615697 66606.92273271662 63695.24249974215 62352.67820025991 65945.56296396891 60361.59306666848 62169.81493106905 64341.65690957763 1.1380972426067966 1.0144115992372236 1.1248610794693954 1.0352068307212305 0.9899534074675149 0.9690872320538322 1.0249279569633298 0.9381417259971635 0.9662451655299961 1.0 15.973465467925116 -6.092921697662779 2.8914758926087933 0.9793609864838593 1.0848279578638826 0.631962979798087 0.037747132611524736 0.17283493911567388 2.8038378195545968 0.011185213141995238 0.015603597245146513 8.073805860656826e-07 6.092921697662779 0.10546697138002337 GDAASS(ph)PAPAASVGSSQGGAR ddPTM_PC-9_AZD4547_30min_R2 2 GDAASSPAPAASVGSSQGGAR 21 0 F8WCC1;E7EXA6;A0A0D9SF58;Q8WVB6;Q8WVB6-2 F8WCC1 CHTF18 Chromosome transmission fidelity protein 18 homolog 1 GDAAS(0.007)S(0.992)PAPAAS(0.001)VGSSQGGAR;GDAAS(0.029)S(0.782)PAPAAS(0.15)VGS(0.029)S(0.009)QGGAR 203.17 2.1726000000000003e-24 57818000.0 25171.0 25011.0 37361.0 50039.0 40316.0 34587.0 27263.0 38079.0 27847.0 31455.0 True False 33174.854410675405 33095.31663323764 36865.56872875627 38503.28164484337 34718.819304815835 32424.269422384048 29689.354184570784 32194.765518369568 29318.935569222747 30353.770024156867 1.09294016473978 1.0903198056419 1.214530145659568 1.2684843304209252 1.1438058362168875 1.0682122647888346 0.9781109285911663 1.0606512961239265 0.9659075477573115 1.0 14.889588093966877 -6.8791913490690035 2.850080220846066 1.0070806222698645 1.1683046536993371 0.6592683992447119 0.05463133098685751 0.18273226068052442 2.9952318414577226 0.023082222181624562 0.020040918350885378 1.3207136028452938e-07 6.8791913490690035 0.16122403142947261 GDALNLS(ph)SPKR ddPTM_PC-9_AZD4547_30min_R2 2 GDALNLSSPKR 11 1 K7EIX9;K7EMC4;A0A0C4DGQ1;Q9BUG6-2;A6NJL1;Q9BUG6 K7EIX9 ZSCAN5A;ZSCAN5B Zinc finger and SCAN domain-containing protein 5A;Zinc finger and SCAN domain-containing protein 5B 1 GDALNLS(0.69)S(0.31)PKR;GDALNLS(0.5)S(0.5)PKR 113.07 0.002364 20353000.0 65002.0 57089.0 70253.0 75459.0 71121.0 71623.0 70784.0 76258.0 58382.0 74382.0 True False 85671.28387440796 75541.90281375809 69321.39931750519 58063.09337992834 61247.07678782138 67144.40248762285 77083.63887322212 64474.07833451048 61467.953330784716 71777.90882011881 1.1935605993914793 1.0524394490660371 0.9657762458813082 0.8089270687091079 0.8532858896922096 0.9354466240566035 1.0739187047981558 0.8982440334962625 0.8563631114529726 1.0 16.13125227179244 -4.981558804593565 1.9815097214089987 0.9179402167669467 1.216491270618761 0.5821021976168278 0.07283130662951678 0.37732924176417826 2.1927262325698433 0.02158294269568697 0.17895666744326263 1.0433768472460352e-05 4.981558804593565 0.29855105385181424 GDATVSYEDPPTAK ddPTM_PC-9_Lapatinib_30min_R1 1 GDATVSYEDPPTAK 14 0 H7BY36;A0A0D9SFL3;B0QYK0;C9JGE3;Q01844-2;Q01844-6;Q01844-3;Q01844;Q01844-5 H7BY36 EWSR1 RNA-binding protein EWS 0 121.68 0.0017457 0.0 22410.0 17373.0 23733.0 25351.0 26369.0 22648.0 22426.0 25285.0 21351.0 20883.0 False True 22090.429290509317 17332.773885893926 21781.76435202931 27215.39710845691 24818.027263448672 21679.397835066608 23587.108548739274 26459.833407430702 18946.225544002566 24492.598725151605 0.9019226395043379 0.7076739418465543 0.8893202634990903 1.1111682110118126 1.0132868113322284 0.8851407757235615 0.9630300489313746 1.0803195571182462 0.7735490119530095 1.0 14.580058235075834 -5.523344964300398 24.99886515574735 0.9777595829070235 0.8032229757389125 0.3218762618518316 0.0997204251319088 15.941801231225087 854804.2652750948 0.026139737661389873 0.045821471057063926 2.996781201116866e-06 5.523344964300398 -0.17453660716811092 GDDDEES(ph)DEEAVKK ddPTM_PC-9_Lapatinib_30min_R1 1 GDDDEESDEEAVKK 14 1 O43395 O43395 PRPF3 U4/U6 small nuclear ribonucleoprotein Prp3 1 GDDDEES(1)DEEAVKK 88.10799999999999 0.00268 20954000.0 42512.0 96051.0 67134.0 61702.0 86068.0 89060.0 102600.0 89634.0 69648.0 75046.0 True False 41905.771084254004 95828.59981085568 61614.50166473419 66239.77091183804 81005.64945619853 85251.111409 107912.12597434442 93798.72286500463 61803.50881404585 88017.60110749076 0.476106716804028 1.0887435990652121 0.7000247778792335 0.7525741451524369 0.9203346653048526 0.9685689036774338 1.226028937582128 1.0656814283140223 0.7021721568913112 1.0 16.42550443161037 -6.488017967649762 2.702532197319008 1.0106740681083752 0.7747018724925453 0.2658647058550305 0.18457099863959078 0.3993163463487606 5.82602131113182 0.06309001172000232 0.06891345485631055 3.250738481381645e-07 6.488017967649762 -0.23597219561582994 GDDGIFDDNFIEER ddPTM_PC-9_AZD4547_30min_R2 2 GDDGIFDDNFIEER 14 0 O60493-4;O60493;O60493-2 O60493-4 SNX3 Sorting nexin-3 0 ; 195.72 5.7445e-07 7294300.0 14485.7 13629.5 16486.4 21865.3 22275.2 18970.5 17655.6 21908.5 14833.900000000001 19857.4 False True 19091.85127872236 18034.96933560083 16267.779563977598 16824.592900517473 19182.672977940096 17784.271636086873 19226.91419657074 18523.044732246115 15617.989669992941 19162.198470122148 0.9963288559238401 0.9411743315215682 0.848951626784497 0.8780095314611479 1.0010684842790807 0.9280914016111591 1.0033772600022641 0.9666450726479737 0.8150416401512924 1.0 14.225975469850615 -6.248397806361426 24.934327994466386 0.9520392679567858 0.9131085037012692 0.07238020131726886 0.06321093882858984 2201.3228758562345 4208732.143847871 0.019143757342546898 0.02455442180974461 5.644197390743274e-07 6.248397806361426 -0.03893076425551667 GDDGIFDDNFIEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GDDGIFDDNFIEER 14 0 O60493-4;O60493;O60493-2 O60493-4 SNX3 Sorting nexin-3 0 ;; 179.83 0.00024974 6008300.0 17203.0 19657.300000000003 20049.0 21589.6 24299.899999999998 21505.7 21486.0 16984.399999999998 18493.0 17138.5 False True 20115.12812526224 21608.746833430123 20527.04419625591 20380.004706427586 19538.50903329171 20377.90323337884 19450.690534830872 16538.57749645932 18763.42513968123 20245.574381708655 0.9935568014032602 1.0673318734267703 1.0139027823681581 1.006639985716601 0.9650755599675275 1.0065361865845475 0.9607378960018077 0.8168984087407019 0.9267914451779393 1.0 14.305318953454792 -7.527184764154454 24.975360431458206 0.9008705670228453 1.0074730825922031 0.4296647505665574 0.048132172487910206 101.18985381981219 586896.7668353216 0.021999752696206992 0.012766264347142708 2.970402049332201e-08 7.527184764154454 0.10660251556935785 GDDGIFDDNFIEER ddPTM_PC-9_Lapatinib_30min_R1 4 GDDGIFDDNFIEER 14 0 O60493-4;O60493;O60493-2 O60493-4 SNX3 Sorting nexin-3 0 ;;; 223.36 1.2031e-19 13466000.0 31766.800000000003 31157.9 45013.899999999994 33633.0 35639.2 36196.0 36167.5 31816.1 43926.3 29362.100000000002 False True 31313.799606682347 31085.75579688566 41313.03090067886 36106.48301639899 33542.97232536309 34647.98145699713 38040.07618106336 33294.39215638344 38978.857529554596 34437.299862461055 0.9092989209881832 0.9026769206946796 1.1996594119074013 1.0484702099352874 0.9740302654194778 1.0061178314030865 1.1046184321358357 0.9668119245515104 1.1318790289956542 1.0 15.071684408818756 GDDLLPAGTEDYIHIR ddPTM_PC-9_Lapatinib_30min_R1 2 GDDLLPAGTEDYIHIR 16 0 K7EM18;P41567;O60739 K7EM18 EIF1;EIF1B Eukaryotic translation initiation factor 1;Eukaryotic translation initiation factor 1b 0 ; 155.06 3.1331e-05 4386800.0 27646.0 26356.0 29966.0 28104.0 27975.0 31286.0 31106.0 28552.0 29837.0 30697.0 False True 27251.762970344516 26294.974301307797 27502.311152105078 30170.861912195687 26329.56550096614 29947.97071122808 32716.51647717307 29878.630154200568 26476.442862461005 36002.935548818576 0.7569316933446215 0.7303563973457897 0.7638907975937966 0.8380111635976232 0.7313171856573827 0.8318202461746432 0.9087180247513637 0.8298942766399232 0.7353967797031434 1.0 15.135826923022753 -14.522878745280089 0.12621024340845502 1.6487228513957188 0.7078176148892028 0.570556398035905 0.05501345455945423 113.82924540665249 0.9125698694433093 18.91782697678189 0.47571591091287707 3.000000000001719e-15 14.522878745280089 -0.940905236506516 GDDLSTAILK ddPTM_PC-9_Lapatinib_30min_R1 2 GDDLSTAILK 10 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 ; 103.7 0.013669999999999998 1524100.0 23191.0 22105.0 23563.0 24765.0 24477.0 21039.2 25705.0 20198.8 22638.5 22385.4 False True 22860.292087291455 22053.817230627166 21625.741095810336 26586.300713618188 23037.310983633553 20139.402460770634 27035.87912446904 21137.309987344717 20088.713736026515 26254.686563329433 0.8707128166298884 0.8399954490955636 0.8236906977977616 1.012630664985806 0.8774551898787599 0.7670783809279915 1.029754404390061 0.8050871198313111 0.7651477265809342 1.0 14.680287351973192 GDDWNDREWDR ddPTM_PC-9_AZD4547_30min_R2 3 GDDWNDREWDR 11 1 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;C9JUL9 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 0 ;; 105.4 0.0033228999999999997 24283100.0 39109.8 30717.0 57416.0 63132.0 59226.0 51750.0 43859.1 56713.0 35921.6 40550.9 False True 51545.902865624405 40645.66954632605 56654.62632505208 48577.89277967691 51003.49221517566 48514.06431920594 47762.47493366499 47949.30898509137 37820.34244060013 39131.22533373334 1.3172575718243331 1.0387016813216725 1.4478112004382488 1.2414099575307704 1.303396246352852 1.2397788187170327 1.2205719224562852 1.2253464739770452 0.9665003361905166 1.0 15.256032666256916 -8.221619566194263 4.570514936661961 0.9798963476251452 1.255093367814952 0.5596862668543335 0.09633130921410991 0.13870347016580556 6.693736319979496 0.07236227728614217 0.0238244374167995 6.00316712158186e-09 8.221619566194263 0.27519702018980685 GDDWNDREWDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GDDWNDREWDR 11 1 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;C9JUL9 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 0 ; 111.27 0.0023767 10871800.0 32168.0 26365.0 34161.0 36345.0 34431.0 39270.0 30142.0 36616.0 29586.0 22338.0 False True 37613.40705303932 28982.342959785146 34975.52779631395 34308.707482079844 27684.492715001594 37210.61206911596 27286.73155081782 35654.8687978589 30018.639278787054 26387.702572489292 1.425414241717787 1.0983276350098365 1.3254480074660977 1.3001778911154114 1.0491437304536047 1.4101497455830116 1.0340699981689887 1.3511926132982552 1.1375995767848022 1.0 14.687578128411467 -14.522878713671712 0.16035289163990926 0.12210772285647518 1.2970522446154438 0.24633485368722685 0.13627240612898395 194.2827316728881 1.7816943570676014 54.143141946583235 0.5328125027384157 3.0000002183446557e-15 14.522878713671712 1.1749445217589687 GDEASEEGQNGS(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 1 GDEASEEGQNGSSPK 15 0 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5 P35611 ADD1 Alpha-adducin 1 GDEAS(0.014)EEGQNGS(0.618)S(0.369)PK 74.85300000000001 0.015571000000000002 3196900.0 13556.0 22150.0 15107.0 15273.0 18512.0 16138.0 18299.0 21614.0 16768.0 18161.0 True False 13362.68895413406 22098.713035891946 13864.960774706391 16396.227369234424 17423.160555992315 15447.815359515413 19246.432682305338 22618.26534578632 14879.411265132085 21300.104651988604 0.627353206590302 1.037493167144077 0.6509339273791757 0.7697721507534308 0.8179847395428486 0.7252459840883075 0.9035839493168155 1.0618851745254054 0.6985604769666202 1.0 14.378572898288548 -7.3532937603855295 6.393946093893531 0.9232310911261704 0.7803623906945207 0.21024657059187568 0.1366042691592027 0.3990377185133162 23.18533883969398 0.054667939116945966 0.03659431072740605 4.4330868482839054e-08 7.3532937603855295 -0.14286870043164968 GDEASEEGQNGSS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GDEASEEGQNGSSPK 15 0 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5 P35611 ADD1 Alpha-adducin 1 GDEASEEGQNGS(0.003)S(0.997)PK;GDEASEEGQNGS(0.093)S(0.907)PK;GDEASEEGQNGS(0.004)S(0.996)PK;GDEASEEGQNGS(0.021)S(0.979)PK 194.67 1.6544e-38 72406000.0 118223.1 178756.0 128384.0 120231.0 144900.0 96333.7 140493.0 94304.5 88034.2 93323.9 True False 138235.93581733922 196501.71432275194 131445.16145903125 113494.84686416101 116507.88517335315 91281.79118621332 127184.48595876379 91829.1067988771 89321.53363065635 110242.7843184139 1.2539227548723078 1.782445132691829 1.1923243981155136 1.0294990966152866 1.0568300310417031 0.8280069462193951 1.153676285891122 0.8329715850939265 0.8102256685813489 1.0 16.750324705106543 -5.5469879637633825 3.171241654625723 0.9581771332296578 1.520342448140637 0.6559565530614986 0.1602645708086967 0.1338895289179044 2.7630116267777174 0.04281355460659291 0.08814912945942723 2.8379976809220473e-06 5.5469879637633825 0.5621653149109791 GDEASEEGQNGSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 GDEASEEGQNGSSPK 15 0 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5 P35611 ADD1 Alpha-adducin 1 GDEASEEGQNGS(0.151)S(0.849)PK;GDEASEEGQNGS(0.035)S(0.965)PK 171.15 0.0001325 83879000.0 44477.0 67864.0 42157.0 50669.0 52151.0 53600.0 54215.0 54022.0 42682.0 41782.0 True False 43842.74982391712 67706.86507755161 38691.01419072598 54395.367286829045 49083.58071281088 51307.65294770268 57021.98742396764 56532.05933700698 37874.70369861448 49003.96302898457 0.8946776365410543 1.3816610105085738 0.7895486772741472 1.1100197601295143 1.0016247192860548 1.0470102778698844 1.163619917643 1.1536221938533773 0.7728906267481382 1.0 15.58061080655418 -8.25561929708568 24.993566285763958 0.8864453109140301 1.070627897958732 0.17081621343897513 0.1596563475607464 714.6432232496717 3068972.355152606 0.1070014122551767 0.03801642627600258 5.5511211148983915e-09 8.25561929708568 0.18418258704470192 GDEELDSLIK ddPTM_PC-9_AZD4547_30min_R2 4 GDEELDSLIK 10 0 Q71UI9;P0C0S5;C9J0D1;A0A494C189;Q71UI9-3;Q71UI9-4;Q71UI9-2;C9J386 Q71UI9 H2AFV;H2AFZ Histone H2A.V;Histone H2A.Z;Histone H2A 0 ;;; 147.4 0.0005225 10251100.0 107480.0 138804.0 137072.0 147697.0 137183.0 147853.0 144924.0 165973.0 140533.0 153640.0 False True 141656.40427712037 183669.678539839 135254.33571874606 113647.73854590279 118137.50840094597 138607.72853695723 157821.95524501096 140325.68653011764 147961.28747619432 148261.11036437625 0.955452201382927 1.2388257317676923 0.9122711639373003 0.7665377540111135 0.7968206100075972 0.9348893192308204 1.0644865322884562 0.9464767003649441 0.9979777374697582 1.0 17.17778069568019 -5.2964813260297 24.451766267316785 0.9202710514039407 1.097139002350873 0.2875014423654375 0.10638693310432788 509.8392988234166 355757.7601769784 0.02947847075280926 0.06136890902739696 5.052643700354185e-06 5.2964813260297 0.1768679509469322 GDEELDSLIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GDEELDSLIK 10 0 Q71UI9;P0C0S5;C9J0D1;A0A494C189;Q71UI9-3;Q71UI9-4;Q71UI9-2;C9J386 Q71UI9 H2AFV;H2AFZ Histone H2A.V;Histone H2A.Z;Histone H2A 0 ;;; 142.43 0.00058449 8861700.0 81790.0 92378.0 99350.0 104532.0 139115.0 96398.0 116847.0 120432.0 89568.0 88230.0 False True 95635.43157386505 101548.67733506663 101718.88078697305 98675.4109373163 111856.41439538314 91342.71918101965 105778.4062609786 117270.78760825148 90877.76255399152 104225.40057170454 0.9175827682050519 0.9743179376432678 0.9759509700036407 0.9467501242120918 1.0732164499423407 0.8763959522341014 1.0149004530637964 1.1251651417503743 0.8719348839678465 1.0 16.669347391334384 -2.5853706051702763 0.5812038625243818 0.9950462095990962 2.8604905300427694e-10 0.06698261992300036 0.07405949321682753 120.03980549347546 3.623692538855359 0.03392356317335052 135.07476860834055 0.002597941663613662 2.5853706051702763 -0.9950462093130471 GDEELDSLIK ddPTM_PC-9_Lapatinib_30min_R1 4 GDEELDSLIK 10 0 Q71UI9;P0C0S5;C9J0D1;A0A494C189;Q71UI9-3;Q71UI9-4;Q71UI9-2;C9J386 Q71UI9 H2AFV;H2AFZ Histone H2A.V;Histone H2A.Z;Histone H2A 0 ;;; 155.42 0.00064517 35528100.0 154895.0 202701.0 188651.0 188944.0 186736.0 181224.0 200263.0 194517.0 160997.0 169091.0 False True 152686.1688957362 202231.65828841185 173140.84299391933 202839.57205870724 175752.55561710146 173473.47197377722 210631.63824561526 203554.96993922035 142863.8224864307 198318.15405040525 0.7699051538011438 1.0197334644261156 0.8730458581714775 1.0227988104767898 0.8862151650142506 0.8747231074452548 1.06208954623529 1.0264061346975026 0.7203769275208154 1.0 17.597457222400465 -4.745097782680398 24.883209625770093 0.9437951717854401 0.7699046268573737 0.2136820926713645 0.09949518010618592 1438.4237625998983 2190150.2183150356 0.023784220691003975 0.6249434794281177 1.7984659396419624e-05 4.745097782680398 -0.17389054492806644 GDEVGSGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GDEVGSGLR 9 0 Q5TGS1 Q5TGS1 HES3 Transcription factor HES-3 0 93.195 0.029688 4462900.0 26687.0 40130.0 30346.0 38815.0 40393.0 33286.0 39038.0 27915.0 23219.0 26777.0 False True 31204.58200772382 44113.84119006937 31069.56372784586 36640.321389927885 32478.281613576677 31540.423563345914 35340.03802935528 27182.26082838736 23558.53394896765 31631.458133384644 0.9865046965631253 1.3946192743960324 0.9822362155051668 1.1583506911196344 1.0267715600280303 0.9971220242312304 1.1172434062423606 0.8593426428135007 0.7447817881055372 1.0 14.949072441674621 -7.257068709813458 0.832253265110807 0.8614393814578839 1.1401013242698828 0.3315632011219799 0.1352251876323531 0.6801908871587039 0.920588978867746 0.1053159747146235 0.06305677004529632 5.5326257051353776e-08 7.257068709813458 0.27866194281199885 GDEVGSGLR ddPTM_PC-9_Lapatinib_30min_R1 1 GDEVGSGLR 9 0 Q5TGS1 Q5TGS1 HES3 Transcription factor HES-3 0 95.815 0.024442 7087700.0 42807.0 46690.0 50982.0 38398.0 47013.0 41875.0 38938.0 44035.0 48792.0 41755.0 False True 42196.56433015763 46581.89217362507 46790.45675621108 41221.91701197302 44247.78777111424 40084.10386539273 40954.019114902745 46081.026857670986 43296.531157462094 48972.29611495979 0.8616415336357417 0.9511886488694878 0.9554474768014357 0.8417395197318668 0.9035269178975186 0.8185057072124511 0.8362691228274334 0.9409611252349347 0.884102535356436 1.0 15.579678219378188 -10.549808552097105 3.2412815725033464 1.000071218728925 0.8890525357007061 0.3388775122370725 0.046851387547861965 8366256.325214834 13291237.605063843 7176.129707859805 0.01289753487223946 2.8196256190500025e-11 10.549808552097105 -0.11101868302821882 GDFCIQVGR ddPTM_PC-9_AZD4547_30min_R2 2 GDFCIQVGR 9 0 Q32Q12;P22392-2;J3KPD9;P22392;E7ERL0;O60361;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1;NME2P1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Putative nucleoside diphosphate kinase;Nucleoside diphosphate kinase A 0 ; 98.58200000000001 0.020346 15402400.0 41627.0 45261.0 48920.0 75056.0 64999.0 55418.0 49776.0 65080.0 52016.0 58755.0 False True 54863.52010461186 59890.73312290464 48271.28883623982 57752.99880364053 55975.01081440924 51952.703699357546 54205.96757111087 55023.38138962396 54765.4595672313 56698.00533363014 0.9676446249171632 1.0563111130715694 0.8513754329132976 1.0186072413624156 0.9872483253164452 0.9163056688440864 0.9560471704805966 0.9704641471220701 0.9659151013333346 1.0 15.79101036082103 GDFNHER ddPTM_PC-9_AZD4547_30min_R2 3 GDFNHER 7 0 V9GYR2;P05026-2;P05026 V9GYR2 ATP1B1 Sodium/potassium-transporting ATPase subunit beta-1 0 ;; 99.802 0.009840100000000001 4979200.0 26803.899999999998 42907.0 39407.0 36047.0 35186.5 22686.0 39105.0 35048.0 39225.0 35520.0 False True 35326.982644245436 56775.84865788364 38884.43743192359 27736.92107059832 30301.461838200743 21267.44083372958 42585.26924357702 29632.136922918602 41298.35342057536 34276.455611446574 1.030648648293963 1.6564095570874435 1.1344357734274655 0.8092120546249133 0.8840313649023154 0.6204679117005127 1.2424058580128026 0.8645041149768995 1.2048606742986527 1.0 15.064930313499234 -5.5180296523681465 11.398026425541241 0.9396022202135906 1.356580207897809 0.3412116936695181 0.22122521918674729 0.2066177629874246 443.6746753380403 0.05691715555924154 0.1052441422014563 3.0336840459713497e-06 5.5180296523681465 0.41697798768421845 GDFNHER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GDFNHER 7 0 V9GYR2;P05026-2;P05026 V9GYR2 ATP1B1 Sodium/potassium-transporting ATPase subunit beta-1 0 ;; 106.04 0.008487999999999999 4683200.0 40097.0 49010.0 46872.0 30094.9 105155.0 40910.0 28618.4 35438.0 41561.0 42623.0 False True 46884.63014815089 53875.38890419382 47989.606243049915 28408.78032198224 84550.63261148354 38764.60758206098 25907.457972726606 34507.79004966471 42168.75099931283 50350.21249651765 0.9311704523867412 1.0700131386321354 0.9531162603607483 0.5642236430272676 1.6792507602094287 0.7698995825438083 0.5145451565774113 0.6853554004772345 0.8375088983433652 1.0 15.61971024650098 -6.971171884992651 24.9998046504933 0.7201440633810329 1.031491242769422 0.1911300124626748 0.2812822868359279 321.4576839239858 278767.90331145824 0.09765862607354643 0.08612561710514333 1.068631852591303e-07 6.971171884992651 0.3113471793883892 GDFNHER ddPTM_PC-9_Lapatinib_30min_R1 2 GDFNHER 7 0 V9GYR2;P05026-2;P05026 V9GYR2 ATP1B1 Sodium/potassium-transporting ATPase subunit beta-1 0 ; 121.09 0.004843699999999999 3470200.0 30634.1 43571.0 14000.6 10018.6 17957.4 7803.2 9567.9 9565.0 22197.6 4989.73 False True 30197.252116394095 43470.114026494266 12849.524711878881 10755.40126506987 16901.181037606773 7469.475326147635 10063.279045905747 10009.424818749245 19697.472536909347 5852.198182102703 5.159984535169002 7.4279975957470725 2.1956749091607195 1.8378395485583912 2.888005585541219 1.2763537894172685 1.7195724978490043 1.7103701049223259 3.365824588297182 1.0 12.514762911195133 -5.2726507575378525 24.60077089130087 2.014752060788226 6.2939909554290585 0.808745980490009 0.8353846630211789 190.28230125481812 417530.97204523126 0.20576505805922682 0.4348512867241718 5.337639548301702e-06 5.2726507575378525 4.279238894640832 GDFS(ph)YIGNLMTK ddPTM_PC-9_Lapatinib_30min_R1 1 GDFSYIGNLMTK 12 0 Q9BPX3 Q9BPX3 NCAPG Condensin complex subunit 3 1 GDFS(1)YIGNLMTK 109.84 0.0022043 0.0 5708.6 7881.4 8144.4 7528.6 5870.4 8080.4 7368.0 7083.1 9311.3 8915.9 True False 5627.194317170973 7863.151102531771 7474.798870293153 8082.278358673373 5525.114613650458 7734.820128332403 7749.478988099125 7412.206684127837 8262.563341664149 10457.001435310018 0.5381269527390233 0.7519508485463503 0.7148128377464977 0.7729059241956352 0.5283651004382458 0.7396785948803964 0.7410804173681723 0.7088271652234012 0.7901465245824736 1.0 13.352181594939744 -9.110371289875706 0.588547282325905 1.0124481574513275 0.6758609931595457 0.5980322713556794 0.07948861836558402 1.4626641910527105 0.8266334074541368 0.11628765409333977 0.033969822320452356 7.755837659709784e-10 9.110371289875706 -0.3365871642917818 GDGGSTTGLSAT(ph)PPASLPGSLTNVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GDGGSTTGLSATPPASLPGSLTNVK 25 0 H7C560;P15056;A0A2R8Y679;A0A2R8Y492;A0A2R8YDP5 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 GDGGS(0.038)T(0.038)T(0.038)GLS(0.037)AT(0.849)PPASLPGSLTNVK 70.229 0.01852 0.0 21634.0 27411.0 28072.0 23713.0 29129.0 23971.0 27617.0 19597.0 21525.0 18916.0 True False 25296.208909023026 30132.182927011978 28741.342943652864 22384.437488583277 23421.381554276115 22713.918561466227 25000.917830234775 19082.599514737853 21839.762403700784 22345.32106102639 1.1320584224293573 1.3484784060483719 1.2862353986840718 1.0017505422029989 1.0481559647458607 1.016495511495815 1.118843527106001 0.8539863653165756 0.9773751893765638 1.0 14.447685153296602 -5.764033837521825 24.99599092322422 1.0036375828213742 1.264879545258763 0.6787297449217171 0.07975457339818881 37.30976993818769 359462.0537451285 0.022533917973614856 0.03523773612730194 1.7217344229343526e-06 5.764033837521825 0.26124196243738873 GDGGSTTGLSAT(ph)PPASLPGSLTNVK ddPTM_PC-9_Lapatinib_30min_R1 1 GDGGSTTGLSATPPASLPGSLTNVK 25 0 H7C560;P15056;A0A2R8Y679;A0A2R8Y492;A0A2R8YDP5 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 GDGGS(0.033)T(0.029)T(0.033)GLS(0.029)AT(0.876)PPASLPGSLTNVK 84.561 0.00079176 0.0 8779.8 10241.0 13444.0 11946.0 13739.0 13659.0 12441.0 14168.0 14610.0 9327.2 True False 8654.598441981867 10217.287593705163 12338.686215340753 12824.54869068778 12930.899031913266 13074.836410684153 13085.134105719484 14826.297002826892 12964.467949879525 10939.394092287215 0.7911405667416045 0.9339902655951329 1.1279131285744706 1.1723271492458331 1.1820489254546698 1.1952066357955349 1.1961479763257743 1.355312449460078 1.1851175522618826 1.0 13.417245212354478 -5.011728522596055 1.2416652911196588 1.2050762525978238 0.6886944908945458 0.7187675015589288 0.08120833665574714 0.48380745814823384 0.8572681691707429 0.02424641466070597 0.28926166053881347 9.733554779847617e-06 5.011728522596055 -0.516381761703278 GDGPICLVLAPTR ddPTM_PC-9_Lapatinib_30min_R1 2 GDGPICLVLAPTR 13 0 P17844-2;P17844;J3KTA4;J3KRZ1;J3QRQ7;A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 P17844-2;A0A1X7SBZ2 DDX5;DDX17 Probable ATP-dependent RNA helicase DDX5;Probable ATP-dependent RNA helicase DDX17 0 ; 136.96 0.00026532 16018200.0 24536.2 29655.0 25929.0 22663.0 23311.0 29646.0 22511.0 23284.0 27921.0 25719.0 False True 24186.30928861198 29586.33566949778 23797.217708834436 24329.71262155177 21939.892811189344 28378.109688201366 23676.509432831066 24365.859642421045 24776.242958835446 30164.494881586645 0.8018138338983446 0.9808331213780148 0.7889148418447745 0.8065678778000487 0.7273416278746356 0.9407785477463525 0.7849131744382019 0.8077662078569972 0.82137105415147 1.0 14.880563803520651 -10.92678169909153 3.59050716814111 1.0012303769310174 0.8299416546780887 0.3396524832189277 0.07154948908417744 103561950.85203078 171422088.4181096 1339247.7448164397 0.017653801556213367 1.1836363686362137e-11 10.92678169909153 -0.17128872225292868 GDGPVQGIINFEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GDGPVQGIINFEQK 14 0 P00441 P00441 SOD1 Superoxide dismutase [Cu-Zn] 0 151.54 0.0011265000000000001 2342200.0 10578.0 12353.0 17279.0 13871.0 22077.0 15310.0 15720.0 15811.0 18410.0 13248.0 False True 12368.646474976684 13579.324201867094 17690.996890972423 13093.852840388763 17751.170331070552 14507.116648285344 14230.887797055808 15395.978003139264 18679.211421701813 15649.757528889693 0.7903410932817312 0.867701891022877 1.1304326510052676 0.8366808761233079 1.1342776588264463 0.9269866719343723 0.9093359926366508 0.9837838046192122 1.193578327793239 1.0 13.933852684338122 -5.050585019487602 6.90443925363734 1.0049110490553597 0.8081849777403216 0.3360646174750628 0.10602553794848213 0.22463655987092898 25.956410806628128 0.02600539715269749 0.07247867714793918 8.900511804364756e-06 5.050585019487602 -0.19672607131503805 GDGPVQGIINFEQK ddPTM_PC-9_Lapatinib_30min_R1 2 GDGPVQGIINFEQK 14 0 P00441 P00441 SOD1 Superoxide dismutase [Cu-Zn] 0 ; 169.04 0.0015030999999999998 23149000.0 38687.0 34982.0 37029.0 35465.0 40091.0 34025.0 33127.0 33311.0 31089.0 36028.0 False True 38135.3162856731 34901.00132828765 33984.61855607355 38073.21440777184 37732.926201938666 32569.83006614894 34842.15396834412 34858.75066778421 27587.42943831651 42255.39179570759 0.902495863014267 0.8259537977312752 0.8042670322494984 0.9010261836369817 0.8929730526311597 0.7707851869795577 0.8245611385357804 0.824953909700235 0.6528735923617424 1.0 15.366847820840718 -6.760046758441281 24.99981655437472 0.8043147840351207 0.8617441545586194 0.0749669727645792 0.08482385365020262 92.19383619237419 1655042.469623163 0.027536476964351398 0.026138265818185614 1.7376137379911899e-07 6.760046758441281 0.057429370523498724 GDHAGVLK ddPTM_PC-9_AZD4547_30min_R2 1 GDHAGVLK 8 0 Q16658 Q16658 FSCN1 Fascin 0 65.24600000000001 0.043898 2534600.0 44434.0 40930.0 39958.0 36345.0 37939.0 41233.0 42769.0 42441.0 57868.0 51761.0 False True 58563.08771538476 54159.82207022575 39428.13081190659 27966.221774652433 32671.82472480918 38654.6939917646 46575.35814546851 35882.718647157824 60926.78434013655 49948.86314482224 1.172460873545537 1.0843054007694675 0.7893699341582263 0.5598970629935438 0.6541054724324789 0.7738853611079954 0.9324608251929067 0.7183890961265547 1.2197832043441073 1.0 15.608164221651386 -10.100202477351946 15.5361597897419 0.9999999999837427 0.8595995252533669 0.02224446415309289 0.2115856506909049 0.0 0.0 0.2168459994216469 0.052592880006357444 7.939579882715407e-11 10.100202477351946 -0.14040047473037576 GDHAGVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GDHAGVLK 8 0 Q16658 Q16658 FSCN1 Fascin 0 ; 81.296 0.015178 4446200.0 50808.0 104016.0 85746.0 66728.0 96858.0 59120.0 54970.0 65496.0 64356.0 63478.0 False True 59408.790896257866 114342.02106220419 87790.50983351567 62989.44649509486 77879.37020097079 56019.643125188064 49762.84365166399 63776.799398748284 65297.08475040966 74986.05890842839 0.7922644790387878 1.5248437206419474 1.1707577529941111 0.8400154296949575 1.0385846560635446 0.747067440810541 0.6636279379935606 0.8505154201613844 0.8707896601173463 1.0 16.194334780315337 -5.743231852223519 6.054598413709904 0.846470516331823 1.2024129933713972 0.3335879305699966 0.19419051374117172 0.16042920354849893 19.863632879157468 0.05230448169889116 0.08750961061765208 1.8062096064650728e-06 5.743231852223519 0.35594247703957416 GDHAGVLK ddPTM_PC-9_Lapatinib_30min_R1 1 GDHAGVLK 8 0 Q16658 Q16658 FSCN1 Fascin 0 71.501 0.029574 4302800.0 31156.0 51145.0 43896.0 52279.0 57348.0 49508.0 67290.0 77011.0 66309.0 57441.0 False True 30711.709726689347 51026.57689483944 40287.04032346012 56123.77205763157 53974.90339050606 47390.65824878475 70773.94694750126 80589.21220247763 58840.58215527456 67369.60031467848 0.4558689614193523 0.7574124925262734 0.5980002870030741 0.8330726588176497 0.8011759478814365 0.7034427698461391 1.0505323857781748 1.1962251791023149 0.8733996027946508 1.0 16.039810119786893 -6.49424041982435 0.592456884598145 1.0577668859243017 0.564072154606813 0.6206510403726894 0.1276244928906465 0.6182966961170213 0.47138731251572086 0.09973380804202998 0.15132840293156577 3.204494866360613e-07 6.49424041982435 -0.49369473131748864 GDHWTTR ddPTM_PC-9_AZD4547_30min_R2 2 GDHWTTR 7 0 K7ER90;K7EL20;K7ENA8;O75821 K7ER90 EIF3G Eukaryotic translation initiation factor 3 subunit G 0 ; 86.47200000000001 0.015602000000000001 2973700.0 13177.0 17049.6 34341.0 37821.0 33895.0 41479.0 32853.0 49612.0 33864.0 31766.0 False True 17367.011901373382 22560.549776900094 33885.6159019892 29101.95277862511 29189.26432028804 38885.31157287617 35776.85335530587 41945.60537034459 35653.9819052738 30653.882008817905 0.566551795833806 0.735976923588677 1.1054265783446826 0.9493725059114415 0.952220808832351 1.2685281284011731 1.1671230855855155 1.368361937267146 1.1631147368224868 1.0 14.903782167991707 -4.568027587723371 0.5792429152903583 1.2017204519440015 6.813679934990381e-17 0.7107222730076819 0.12361388845936701 2.5698047547149674 0.5486126917187463 0.06560268046243696 2.187268177114978 2.703786605799151e-05 4.568027587723371 -1.2017204519440015 GDIS(ph)ISGPK ddPTM_PC-9_AZD4547_30min_R2 1 GDISISGPK 9 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GDIS(0.981)IS(0.019)GPK 93.258 0.0063955 5488700.0 28963.0 34036.0 48677.0 65657.0 49713.0 43528.0 35551.0 48361.0 47240.0 52195.0 True False 38172.63153217558 45037.47138974353 48031.5111750132 50520.79304053798 42811.20805884284 40806.18727896418 38714.97012858732 40887.918675224406 49737.00995762855 50367.66893692153 0.7578796545057798 0.894174226052563 0.9536179098374784 1.0030401268680553 0.8499739805798419 0.8101662860369462 0.7686472482391912 0.8117889816666086 0.9874788928571859 1.0 15.620210342807534 -8.27960493679566 21.23101025902651 0.9937399686889009 0.8609161844412965 0.3570171992566731 0.07363162648515136 171.46677987465696 200388.43310935097 0.07851525050028955 0.020571835039599296 5.2528507729467474e-09 8.27960493679566 -0.13282378424760444 GDIS(ph)ISGPK ddPTM_PC-9_Lapatinib_30min_R1 1 GDISISGPK 9 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GDIS(0.971)IS(0.029)GPK 86.189 0.011855 4554200.0 42904.0 43765.0 42805.0 31163.0 28252.0 30862.0 32117.0 23800.0 26342.0 22926.0 True False 42292.181092370025 43663.66483141359 39285.738132078295 33454.83097672054 26590.272905569098 29542.104202835813 33779.86111031208 24905.83488617166 23375.086566442606 26888.7285530252 1.5728590888546052 1.6238649865986716 1.461048559979543 1.2441953479037446 0.9889003436191659 1.0986798481221636 1.256283317513411 0.9262555809233141 0.8693265849423258 1.0 14.71471391781666 -5.827855842971551 1.7618962140303327 1.031318256737286 1.602921525958759 0.8492267700202212 0.10057455555349332 0.1403019892144033 0.8887904952793078 0.034820616126695604 0.06779924266541336 1.486428956457395e-06 5.827855842971551 0.571603269221473 GDISIS(ph)GPK ddPTM_PC-9_Lapatinib_30min_R1 1 GDISISGPK 9 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GDIS(0.287)IS(0.713)GPK 81.017 0.037592 0.0 34503.0 35560.0 49456.0 42913.0 32182.0 34614.0 29932.0 29108.0 32000.0 23781.0 True False 34010.98089292474 35477.6630047999 45389.918585680745 46068.9651735715 30289.118032246366 33133.639909175006 31481.732501599206 30460.463943978342 28395.823025061232 27891.514163809316 1.219402456717669 1.271987701938176 1.627373771072512 1.651719763330324 1.0859617679540707 1.1879469760794708 1.128720811523685 1.092105066977768 1.0180810858202272 1.0 14.767538636515987 -6.284024732734321 24.790172655845826 1.0973609601821275 1.4436294640082215 0.6266131330752027 0.13487531223598717 530.0813433473892 581827.060077393 0.045999518906033994 0.05219599434045708 5.199663840075383e-07 6.284024732734321 0.346268503826094 GDKEEVAYEER ddPTM_PC-9_AZD4547_30min_R2 2 GDKEEVAYEER 11 1 F5GWX2;Q9NRV9 F5GWX2 HEBP1 Heme-binding protein 1 0 ; 87.184 0.013625 24239000.0 80926.0 74423.0 99634.0 120330.0 105715.0 100604.0 90211.0 123216.0 86624.0 110067.0 False True 106658.78463463174 98478.77932891305 98312.78806030077 92589.7775799678 91038.29702372762 94313.21597622015 98239.60423813648 104175.79842200238 91202.76779359902 106213.58783178715 1.0041915240030272 0.9271768456299218 0.925614039288466 0.8717319456961036 0.8571247698355413 0.88795810311564 0.9249250142431941 0.9808142305388264 0.858673260694657 1.0 16.696608815377154 -9.989052454206554 11.387138932401937 0.9999999989898082 0.9144110043377596 0.2282181648722561 0.046667564775808745 0.0 0.0 0.04676782165953754 0.011342862857783692 1.0255280552113876e-10 9.989052454206554 -0.08558899465204861 GDKEEVAYEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GDKEEVAYEER 11 1 F5GWX2;Q9NRV9 F5GWX2 HEBP1 Heme-binding protein 1 0 94.465 0.008583499999999999 11158000.0 44595.0 38490.0 50688.0 54516.0 56273.0 55877.0 62142.0 53896.0 46433.0 36684.0 False True 52144.05270860138 42311.032828451775 51896.5941553105 51461.64526325668 45246.7096091105 52946.711754163305 56255.459890880564 52481.287107532306 47111.99478239435 43334.51880961578 1.2032913746588274 0.976381738870563 1.197580948880753 1.1875439413403044 1.0441262728194967 1.2218137689904291 1.2981674064048374 1.2110734940452803 1.0871701377226406 1.0 15.403229064446924 GDKEEVAYEER ddPTM_PC-9_Lapatinib_30min_R1 1 GDKEEVAYEER 11 1 F5GWX2;Q9NRV9 F5GWX2 HEBP1 Heme-binding protein 1 0 79.65899999999999 0.022080000000000002 10588000.0 33695.0 31207.0 37151.0 31906.0 33651.0 29974.0 26126.0 24443.0 34836.0 27408.0 False True 33214.50312109376 31134.74210885235 34096.58818700714 34252.473675295856 31671.714340411512 28692.08189280671 27478.67644450021 25578.711013558554 30912.40284065727 32145.436281135633 1.0332571886910584 0.9685587041518425 1.0606976333687692 1.065547015001838 0.9852631665477777 0.892570928012089 0.8548235651300187 0.795718272101016 0.9616420374670117 1.0 14.972326310821993 -6.668778692949117 3.354787664980943 0.8841994770307197 1.0292894599090678 0.5210799962250916 0.05852778202994714 0.17647739477280858 3.9291631017955035 0.020290361978015623 0.019908113859074806 2.1439828499742024e-07 6.668778692949117 0.14508998287834818 GDLAFGAPGPRPPS(ph)PFDDPADDPEHK ddPTM_PC-9_AZD4547_30min_R2 2 GDLAFGAPGPRPPSPFDDPADDPEHK 26 1 Q7Z3Z5;Q93074-3;Q93074;Q93074-2 Q7Z3Z5 TNRC11;MED12 Mediator of RNA polymerase II transcription subunit 12 1 GDLAFGAPGPRPPS(1)PFDDPADDPEHK;GDLAFGAPGPRPPS(1)PFDDPADDPEHK 67.877 0.00015742 18035500.0 25277.9 36460.0 29999.0 32537.0 27797.0 39264.0 35693.0 45594.0 38379.0 32236.0 True False 33315.74638701727 48244.981985839964 29601.193659001598 25036.0973416389 23937.86636114608 36808.815873029984 38869.607853496855 38548.49494588992 40407.63558771863 31107.427451874748 1.0709900855208596 1.5509151973585134 0.9515796092363024 0.8048269944652736 0.7695225327835143 1.1832806145726984 1.2495282007369692 1.2392054921779372 1.2989706606318352 1.0 14.924971470150357 -6.974178294459495 24.989961112147835 1.2167950010254254 1.0351813888384727 0.1274000098802177 0.21288899932910388 494.4987740982386 478568.87991113996 0.08262763150024703 0.07286838850317477 1.0612597801109947e-07 6.974178294459495 -0.1816136121869527 GDLAFGAPGPRPPS(ph)PFDDPADDPEHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GDLAFGAPGPRPPSPFDDPADDPEHK 26 1 Q7Z3Z5;Q93074-3;Q93074;Q93074-2 Q7Z3Z5 TNRC11;MED12 Mediator of RNA polymerase II transcription subunit 12 1 GDLAFGAPGPRPPS(1)PFDDPADDPEHK;GDLAFGAPGPRPPS(1)PFDDPADDPEHK 73.153 5.4678e-05 6587900.0 42046.9 51254.0 35673.5 43361.0 44400.0 30644.8 45666.8 34671.9 33300.6 32263.9 True False 49164.60970587042 56342.158394114485 36524.09153250213 40931.623748258724 35700.138728066864 29037.73274091279 41340.91010499926 33761.79936291468 33787.55827645426 38113.08966910813 1.2899665215470553 1.4782889260164493 0.9583083357869584 1.0739518654514937 0.9366897052432609 0.7618834629523304 1.084690600103916 0.8858321289622366 0.8865079837345267 1.0 15.21799894570588 -5.27008524543924 24.788955548705523 0.9466656957232492 1.3841277268384065 0.7568827894825947 0.09875681471422516 224.5321882493718 643767.8086215501 0.025698904188393698 0.054858012468021855 5.369263954944504e-06 5.27008524543924 0.43746203111515725 GDLAFGAPGPRPPS(ph)PFDDPADDPEHK ddPTM_PC-9_Lapatinib_30min_R1 2 GDLAFGAPGPRPPSPFDDPADDPEHK 26 1 Q7Z3Z5;Q93074-3;Q93074;Q93074-2 Q7Z3Z5 TNRC11;MED12 Mediator of RNA polymerase II transcription subunit 12 1 GDLAFGAPGPRPPS(1)PFDDPADDPEHK;GDLAFGAPGPRPPS(1)PFDDPADDPEHK 62.295 0.00060534 13115100.0 25880.9 43804.3 37421.6 38282.2 42890.8 44797.0 48861.0 49394.0 40820.7 34850.2 True False 25511.83362002421 43702.87383467819 34344.94049955335 41097.60069367552 40368.047470557234 42881.13673690741 51390.78350129084 51689.025561662296 36223.04290497239 40874.01063502744 0.624157826052958 1.0692093375644065 0.8402635309323199 1.0054702255828176 0.9876213966623424 1.0491051910663238 1.2572973070876226 1.2645939255436514 0.8862121025610991 1.0 15.318896189812424 -3.9384918037815084 0.5204473646972837 1.1052527490508313 8.783844042430608e-14 0.41508283977916016 0.13751311555674922 9.855541371180486 1.0542162900390968 0.07774339783551885 8.014976354921101 0.00011521478035191245 3.9384918037815084 -1.1052527490507433 GDLGIEIPAEK ddPTM_PC-9_AZD4547_30min_R2 1 GDLGIEIPAEK 11 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BR70;P30613-2;P30613 P14618 PKM;PKLR Pyruvate kinase PKM;Pyruvate kinase;Pyruvate kinase PKLR 0 94.465 0.030510000000000002 14855000.0 40281.0 36522.0 48924.0 65246.0 56103.0 50884.0 46868.0 58087.0 39180.0 44298.0 False True 53089.52010315106 48327.02227336392 48275.23579362625 50204.542740651326 48314.066858271704 47702.215436105784 51039.161204653356 49110.988856470336 41250.9748124447 42747.140503261835 1.2419431914773351 1.130532281327129 1.1293208206509764 1.1744538266090676 1.1302292104096432 1.115915939043124 1.1939783715067163 1.1488719076477854 0.9649996310115067 1.0 15.383540296162238 -8.256254083081657 23.66204691310759 0.9824997920729486 1.1556722480615371 0.7853973317250615 0.03670949315293325 79.75296700346838 363945.6386013156 0.0259227473252146 0.009105225738028938 5.54301325240702e-09 8.256254083081657 0.17317245598858855 GDLGIEIPAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GDLGIEIPAEK 11 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BR70;P30613-2;P30613 P14618 PKM;PKLR Pyruvate kinase PKM;Pyruvate kinase;Pyruvate kinase PKLR 0 ;;; 152.07 0.00062411 34731600.0 165410.0 158213.0 166190.0 169886.0 178221.0 153913.0 174201.0 151837.0 158985.0 144726.0 False True 193410.64600358222 173919.34104670965 170152.59987908433 160367.83819784332 143299.8744201533 145841.53133164882 157699.42017397744 147851.43963459958 161309.85485492973 170963.67814961405 1.131296706393532 1.0172882505166334 0.9952558445202616 0.9380228592034732 0.8381889999743013 0.8530556484870413 0.9224147601455511 0.8648119953596901 0.943532898922331 1.0 17.383330326334757 -5.111118187698746 1.0912352496865878 0.8964802643100478 1.1625535393905229 0.6758305878245212 0.04832709866727896 0.5908874651789772 0.8423949813644085 0.015781322490535123 0.15974362638332246 7.742510665867682e-06 5.111118187698746 0.26607327508047507 GDLGIEIPAEK ddPTM_PC-9_Lapatinib_30min_R1 3 GDLGIEIPAEK 11 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BR70;P30613-2;P30613 P14618 PKM;PKLR Pyruvate kinase PKM;Pyruvate kinase;Pyruvate kinase PKLR 0 ;; 175.86 0.0018047 135323000.0 652511.0 671199.0 743725.0 654612.0 659654.0 599369.0 677986.0 589839.0 591052.0 627887.0 False True 643206.073484137 669644.879953844 682578.8013615226 702754.3502016154 620854.4486496636 573735.3850673804 713088.7976690237 617245.0732531347 524481.4997065158 736416.4313431642 0.8734271074193455 0.9093290853552327 0.92689241074721 0.9542893399592511 0.8430752251375966 0.7790909608316768 0.968322768638401 0.8381739556344899 0.7122077636832517 1.0 19.49016229171783 -6.279934985307143 23.682121689737805 0.8504099768503485 0.9162882386795571 0.11287069532481975 0.0800702288575871 857.5046366034823 1097961.4173971438 0.02451723915428196 0.02786254506331557 5.24886030785008e-07 6.279934985307143 0.06587826182920864 GDLGPAS(ph)PSQELGSQPVPGGDGAPALGK ddPTM_PC-9_Lapatinib_30min_R1 1 GDLGPASPSQELGSQPVPGGDGAPALGK 28 0 H3BLU1;Q4KMQ1;Q4KMQ1-2;Q4KMQ1-4;Q4KMQ1-3 H3BLU1 TPRN Taperin 1 GDLGPAS(0.899)PS(0.098)QELGS(0.003)QPVPGGDGAPALGK 101.9 3.6733999999999994e-10 4220300.0 39355.0 47996.0 50614.0 38157.0 59319.0 51689.0 47685.0 50084.0 57748.0 47128.0 True False 38793.790483176905 47884.868210865454 46452.71229569001 40963.19306802058 55829.9730456411 49478.38196294409 50153.895975503045 52411.085480631125 51243.812126601144 55274.01200588733 0.7018450276242824 0.8663179398985034 0.8404078265703285 0.7410931752820388 1.0100582718637205 0.8951472883436444 0.9073684749021126 0.9482048358467037 0.9270868943101702 1.0 15.754313712400618 -2.2465245614963996 0.2200941649086527 0.9914539685342918 8.843908610782177e-10 0.5776327415014395 0.06227191628743236 28.58261957168064 0.48244809367156477 0.09914237579875353 9.424220945525768 0.005668595119135161 2.2465245614963996 -0.9914539676499009 GDLGPASPS(ph)QELGSQPVPGGDGAPALGK ddPTM_PC-9_AZD4547_30min_R2 1 GDLGPASPSQELGSQPVPGGDGAPALGK 28 0 H3BLU1;Q4KMQ1;Q4KMQ1-2;Q4KMQ1-4;Q4KMQ1-3 H3BLU1 TPRN Taperin 1 GDLGPAS(0.462)PS(0.537)QELGS(0.001)QPVPGGDGAPALGK 108.9 1.0721e-10 6164200.0 21691.0 24563.0 26811.0 27769.0 27754.0 26089.0 26614.0 31919.0 30346.0 23296.0 True False 28588.28679917205 32502.50939435513 26455.46862200379 21367.286076773235 23900.83616891205 24457.65070577319 28982.59444185038 26986.65197565163 31950.027607413125 22480.41413075054 1.2716975155749761 1.4458145301645289 1.176823009938053 0.950484539675153 1.0631848697225974 1.0879537433573354 1.289237568012843 1.200451727387757 1.4212383909649278 1.0 14.456380992460462 -5.362480728349587 6.40441165551286 1.147100770940988 1.3572314943648252 0.2783005192240773 0.13583863336207005 0.30134856697766 15.991159620177093 0.03758074952114481 0.07933051011062352 4.34029523110394e-06 5.362480728349587 0.2101307234238372 GDMEQNDSDNRR ddPTM_PC-9_AZD4547_30min_R2 1 GDMEQNDSDNRR 12 1 Q9UN86-2;Q9UN86 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 0 98.182 0.0034680999999999996 10531000.0 19608.0 17427.0 21989.0 34515.0 28242.0 22809.0 23444.0 30686.0 18316.0 21805.0 False True 25842.93612826359 23059.936946440856 21697.411492642645 26558.100001434283 24321.085792405214 21382.749624285363 25530.47058295411 25944.183794130317 19284.146367144887 21041.61358692545 1.228182240943799 1.0959205600453343 1.0311667117641912 1.2621703127338386 1.1558564979787251 1.0162124466334599 1.2133323557855793 1.2329940233410217 0.9164765947002945 1.0 14.360957722230733 -8.269166644920753 24.99816136475784 0.9582382736347034 1.1494054783650032 0.47415184989599246 0.08252666921440323 585.1077564629333 1892832.2187308755 0.07517371290340456 0.020861111713413615 5.380632804269781e-09 8.269166644920753 0.1911672047302998 GDMEQNDSDNRR ddPTM_PC-9_Lapatinib_30min_R1 2 GDMEQNDSDNRR 12 1 Q9UN86-2;Q9UN86 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 0 ; 128.08 0.00013621 15208100.0 84873.0 70817.0 98136.0 77647.0 76779.0 78607.0 62554.0 80056.0 85988.0 64831.0 False True 83662.69545619802 70653.02758748358 90067.63689591493 83357.41940279889 72263.0101733219 75245.16185186678 65792.74004092733 83775.69401879668 76303.12594621765 76036.95196812245 1.1002899681101443 0.9291933166535132 1.1845245576607892 1.096275129988712 0.9503670031857311 0.9895867720133282 0.8652732433108329 1.1017760687450835 1.0035005871646039 1.0 16.214413080544197 -6.256611929624445 24.84117420964998 0.9844073550687487 1.0746119157829652 0.24218902850568624 0.08007348107767842 603.1607611578168 3103756.340543112 0.02432298520370162 0.030357106677981024 5.538447845196361e-07 6.256611929624445 0.09020456071421656 GDMS(ph)DEDDENEFFDAPEIITMPENLGHK ddPTM_PC-9_AZD4547_30min_R2 6 GDMSDEDDENEFFDAPEIITMPENLGHK 28 0 P22059 P22059 OSBP Oxysterol-binding protein 1 1 GDMS(1)DEDDENEFFDAPEIITMPENLGHK;GDMS(1)DEDDENEFFDAPEIITMPENLGHK;GDMS(1)DEDDENEFFDAPEIITMPENLGHK;GDMS(1)DEDDENEFFDAPEIITMPENLGHK;GDMS(1)DEDDENEFFDAPEIITMPENLGHK;GDMS(0.999)DEDDENEFFDAPEIIT(0.001)MPENLGHK 108.49 1.0406e-10 56999900.0 67632.2 72747.2 94841.5 79978.7 77750.79999999999 105743.80000000002 85350.6 99112.1 92471.8 88514.8 True False 89137.83276284926 96261.30975096811 93583.83974166473 61540.846373597284 66956.44349649952 99131.6234697051 92946.638053979 83796.6023144828 97359.67056307863 85415.92379380821 1.0435739473827579 1.1269714764584222 1.0956252134856455 0.7204844675350613 0.783887131609448 1.1605754415184484 1.0881652264084825 0.9810419251188526 1.1398304465816271 1.0 16.382217431091014 -8.227880960281228 24.137666028062434 1.0699154033383125 0.999222775686606 0.03836091004116582 0.1398917232852065 1576.0307828932391 1133599.4067230707 0.10397597363456013 0.039294758799600045 5.917238029004341e-09 8.227880960281228 -0.07069262765170647 GDMS(ph)DEDDENEFFDAPEIITMPENLGHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GDMSDEDDENEFFDAPEIITMPENLGHK 28 0 P22059 P22059 OSBP Oxysterol-binding protein 1 1 GDMS(0.995)DEDDENEFFDAPEIIT(0.005)MPENLGHK;GDMS(1)DEDDENEFFDAPEIITMPENLGHK 104.57 1.8078e-10 38792000.0 28074.1 38186.0 39339.4 30714.0 41594.0 31209.6 37498.3 26351.5 28198.1 24089.9 True False 32826.49064125005 41976.853717517784 40277.40049150531 28993.194156131525 33443.95428502733 29572.913634639208 33946.18955981796 25659.801046722154 28610.44386693589 28457.208174456537 1.1535386900924252 1.4750868553295615 1.4153672505252533 1.0188348055223524 1.175236659900002 1.0392064271850863 1.1928854493283845 0.9016977663239164 1.0053847760307315 1.0 14.796506511180757 -5.763594067020919 24.999994938559645 1.0545318067929284 1.3607065600557458 0.6054384725303341 0.11088604782238179 36.51114301940944 423633.40175295254 0.030844771530340435 0.048394166415009356 1.7234787497176012e-06 5.763594067020919 0.3061747532628174 GDMS(ph)DEDDENEFFDAPEIITMPENLGHK ddPTM_PC-9_Lapatinib_30min_R1 6 GDMSDEDDENEFFDAPEIITMPENLGHK 28 0 P22059 P22059 OSBP Oxysterol-binding protein 1 1 GDMS(1)DEDDENEFFDAPEIITMPENLGHK;GDMS(0.868)DEDDENEFFDAPEIIT(0.132)MPENLGHK;GDMS(0.981)DEDDENEFFDAPEIIT(0.019)MPENLGHK;GDMS(1)DEDDENEFFDAPEIITMPENLGHK;GDMS(1)DEDDENEFFDAPEIITMPENLGHK;GDMS(0.877)DEDDENEFFDAPEIIT(0.123)MPENLGHK 100.33 2.0881e-07 19449500.0 18731.699999999997 41241.7 44650.8 34381.6 41794.1 41376.59999999999 46373.200000000004 48866.3 47441.6 38098.6 True False 18464.58252302691 41146.20737753248 40979.78358107237 36910.13755765538 39335.85320836209 39607.01927156557 48774.17739018974 51136.80669319876 42098.227425804536 44683.892246806536 0.4132268160759101 0.9208286321671791 0.9171041626079722 0.8260278078235959 0.8803139393295207 0.8863824810247187 1.0915382465070627 1.14441254156532 0.9421342973722977 1.0 15.447467238615834 -4.756957517958338 4.488201144516469 0.9583196414069509 0.3643909571760715 0.7588074385197305 0.09212416670508453 0.11831917249676543 5.195567266004023 0.026486520853101502 0.22950174366426748 1.7500178644026474e-05 4.756957517958338 -0.5939286842308794 down GDMS(ph)DEDDENEFFDAPEIITMPENLGHKR ddPTM_PC-9_AZD4547_30min_R2 4 GDMSDEDDENEFFDAPEIITMPENLGHKR 29 1 P22059 P22059 OSBP Oxysterol-binding protein 1 1 GDMS(1)DEDDENEFFDAPEIITMPENLGHKR;GDMS(1)DEDDENEFFDAPEIITMPENLGHKR;GDMS(1)DEDDENEFFDAPEIITMPENLGHKR;GDMS(1)DEDDENEFFDAPEIITMPENLGHKR 78.317 1.2104e-06 13835400.0 18725.100000000002 9425.5 25245.5 43010.1 35572.9 22644.5 18205.8 23749.2 17333.3 26054.699999999997 True False 24679.292293724433 12472.108549301562 24910.72817488332 33094.7859444209 30634.216867950254 21228.53583529002 19826.08093069211 20079.30684232418 18249.502851366717 25142.53288343348 0.981575420747912 0.4960561693257041 0.9907803756437404 1.3162868712494435 1.2184220663040384 0.8443276552012622 0.7885474793892225 0.7986190944013647 0.7258418607216535 1.0 14.61784237514318 -6.973177720027772 24.877519100116626 0.8121798255280863 0.9937618439572519 0.13649418490420973 0.2111482864435659 464.40939709583085 430735.6938914359 0.08318771057751158 0.07336293093783125 1.0637076435083354e-07 6.973177720027772 0.18158201842916555 GDMS(ph)DEDDENEFFDAPEIITMPENLGHKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GDMSDEDDENEFFDAPEIITMPENLGHKR 29 1 P22059 P22059 OSBP Oxysterol-binding protein 1 1 GDMS(1)DEDDENEFFDAPEIITMPENLGHKR;GDMS(1)DEDDENEFFDAPEIITMPENLGHKR 76.471 1.6011000000000002e-06 4920700.0 10382.1 4422.0 11068.3 15693.9 13687.9 18295.1 13384.5 15996.4 14520.1 13319.6 True False 12139.58447417805 4860.986936020103 11332.210248761496 14814.621663310303 11005.854254412308 17335.67274931713 12116.623264611548 15576.511449586797 14732.428993169606 15734.338042104406 0.7715344898331946 0.3089413055072487 0.7202216082072848 0.9415471832159077 0.6994799669970939 1.10177324924173 0.7700751841093022 0.9899692893278845 0.9363234064087262 1.0 13.941628863971493 -5.546670756267253 4.576359919020375 0.909290238028675 0.531943463340985 0.5093722139883919 0.15012076268057356 0.13614484045020936 6.995151298985285 0.03823374483248223 0.07218232629360272 2.840071303821348e-06 5.546670756267253 -0.37734677468769007 GDMS(ph)DEDDENEFFDAPEIITMPENLGHKR ddPTM_PC-9_Lapatinib_30min_R1 3 GDMSDEDDENEFFDAPEIITMPENLGHKR 29 1 P22059 P22059 OSBP Oxysterol-binding protein 1 1 GDMS(1)DEDDENEFFDAPEIITMPENLGHKR;GDMS(1)DEDDENEFFDAPEIITMPENLGHKR;GDMS(1)DEDDENEFFDAPEIITMPENLGHKR 70.42399999999999 3.1204e-05 5907800.0 19028.4 12122.8 17553.4 11857.599999999999 12996.9 12948.0 8000.8 7942.5 16359.7 8147.0 True False 18757.051526618816 12094.73040142261 16110.227210083483 12729.647459794027 12232.447894888535 12394.244223262198 8415.04227578494 8311.53754552178 14517.09831072169 9555.198094804873 1.9630206868046993 1.2657749511230407 1.686017082036484 1.3322222452630355 1.2801877861160484 1.2971205934496433 0.8806769040570878 0.8698446084587962 1.5192880531293835 1.0 13.222070067590632 -1.522878745334006 0.29161036550469527 1.0249883984480672 7.575279729704302 0.5145033954180527 0.2299658418090541 43.83209294650997 0.6225152158390546 0.24138150222482313 148.32501011221055 0.029999999996292714 1.522878745334006 6.550291331256235 GDPGPQGIS(ph)GK ddPTM_PC-9_Lapatinib_30min_R1 1 GDPGPQGISGK 11 0 P12107-4;P12107-3;P12107;P12107-2 P12107-4 COL11A1 Collagen alpha-1(XI) chain 1 GDPGPQGIS(1)GK 88.681 0.0096954 8516000.0 44803.0 41680.0 52761.0 29940.0 44109.0 46647.0 46455.0 48639.0 52974.0 23187.0 True False 44164.101004136086 41583.49252081158 48423.1942433497 32141.887476912147 41514.59534163057 44652.01654946801 48860.21259393929 50898.94550539931 47007.510279049806 27194.842055264562 1.6239881413683923 1.5290948348332682 1.7806021503984286 1.181911165786304 1.5265613698827825 1.6419296151353808 1.7966720488630528 1.8716396808616855 1.728545074228507 1.0 14.73104542635844 -6.819310430467122 4.81941483359515 1.6769708781008879 1.523038652785251 0.0 0.2657857194329413 0.6102213564474124 28.735619789366204 0.09170982853931853 0.0821077821469812 1.5159663785941637e-07 6.819310430467122 -0.15393222531563677 GDPGS(ph)SPAGPR ddPTM_PC-9_AZD4547_30min_R2 2 GDPGSSPAGPR 11 0 H3BRW8;Q9P1Z2-4;Q9P1Z2-2;Q9P1Z2-3;Q9P1Z2 H3BRW8 CALCOCO1 Calcium-binding and coiled-coil domain-containing protein 1 1 GDPGS(0.5)S(0.5)PAGPR;GDPGS(0.5)S(0.5)PAGPR 79.23 0.017509999999999998 19555600.0 38085.0 41041.0 72628.0 99525.0 81145.0 62747.0 53653.0 79603.0 51291.0 61701.0 True False 50195.237782788594 54306.70064950242 71664.90526570776 76581.04889592192 69879.41741465613 58823.42017076743 58428.013060366684 67302.18544496367 54002.13754734814 59540.86677032279 0.8430384121953632 0.9120912004688978 1.2036254954458943 1.286193047731924 1.1736378928478486 0.9879503500961299 0.9813094136797016 1.1303527996087117 0.9069760061716914 1.0 15.861592603412 -8.265607646241747 24.90861128033137 0.9534880042240179 1.069980107744123 0.10105240960310957 0.13204108304053688 922.9863098137653 5515432.049997944 0.12459481567175465 0.03674761536742373 5.424907703882392e-09 8.265607646241747 0.1164921035201052 GDPGS(ph)SPAGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GDPGSSPAGPR 11 0 H3BRW8;Q9P1Z2-4;Q9P1Z2-2;Q9P1Z2-3;Q9P1Z2 H3BRW8 CALCOCO1 Calcium-binding and coiled-coil domain-containing protein 1 1 GDPGS(0.5)S(0.5)PAGPR;GDPGS(0.5)S(0.5)PAGPR 89.561 0.0092155 16969700.0 39768.0 53503.0 62182.0 65942.0 64942.0 65143.0 52292.0 58484.0 51879.0 43973.0 True False 46499.936946197085 58814.42425099129 63664.65470654821 62247.48352684844 52217.08129004773 61726.786402302554 47338.52319870501 56948.85696892014 52637.632229574585 51944.956809923526 0.89517712212851 1.132245127591586 1.2256176271261383 1.1983354564067463 1.005238708372017 1.188311439514188 0.9113208693564934 1.096330817586524 1.0133347963342367 1.0 15.664696068265174 -7.251761051955884 24.90010232965288 1.0132741855417806 1.113464239935772 0.19354470899594545 0.10127559643689495 1156.1308770159742 2974463.048629242 0.03948510660376107 0.030205249977501878 5.600656638622508e-08 7.251761051955884 0.10019005439399131 GDPGS(ph)SPAGPR ddPTM_PC-9_Lapatinib_30min_R1 1 GDPGSSPAGPR 11 0 H3BRW8;Q9P1Z2-4;Q9P1Z2-2;Q9P1Z2-3;Q9P1Z2 H3BRW8 CALCOCO1 Calcium-binding and coiled-coil domain-containing protein 1 1 GDPGS(0.5)S(0.5)PAGPR 97.45200000000001 0.0053847 7174300.0 40045.0 30188.0 44421.0 32871.0 39886.0 38432.0 34747.0 31122.0 44790.0 28033.0 True False 39473.95095664641 30118.10154074521 40768.87685001869 35288.442994441524 37539.98389889313 36788.35294936773 36546.02964162327 32568.041736446816 39745.27854039038 32878.46669837547 1.2006019416531009 0.9160433732219437 1.23998716923235 1.0732995342567215 1.1417802491607063 1.1189193610170831 1.1115490870329732 0.9905584112307769 1.20885438195797 1.0 15.0048553994258 -10.69787647386814 4.347481826835985 0.9999725988239896 1.1057916973977464 0.10838502417003348 0.09458269419533381 2.304857467024271e-05 4.373965037557602e-06 0.08402778268881377 0.020374454963051604 2.005042239289668e-11 10.69787647386814 0.10581909857375682 GDPPRLS(ph)PDPVAGSAVSQELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GDPPRLSPDPVAGSAVSQELR 21 1 E9PMR3;E9PMG4;Q9BUR4 E9PMR3 WRAP53 Telomerase Cajal body protein 1 1 GDPPRLS(0.981)PDPVAGS(0.01)AVS(0.01)QELR 43.534 0.041763 31193000.0 43568.0 54159.0 61251.0 50494.0 80983.0 73434.0 68163.0 50763.0 71222.0 34484.0 True False 50943.20189277598 59535.5475956383 62711.456135711065 47664.98488375676 65114.962491329716 69582.99176683123 61706.1071826155 49430.52503784443 72263.48701121387 40735.67622480622 1.2505795070551406 1.4615087587372317 1.539472569195318 1.1701041765137288 1.598475059846376 1.7081585041776788 1.514792754196117 1.2134455499168424 1.773960658279403 1.0 15.314005237122029 -10.643500962605495 4.537308704911622 0.9999610818491108 1.4675720583740162 0.3455717968736449 0.19403114171145172 135795083.4102388 6.5542817416320736 67878.13132474443 0.04611000783678418 2.2724745983683468e-11 10.643500962605495 0.46761097652490535 GDPPRLS(ph)PDPVAGSAVSQELR ddPTM_PC-9_Lapatinib_30min_R1 2 GDPPRLSPDPVAGSAVSQELR 21 1 E9PMR3;E9PMG4;Q9BUR4 E9PMR3 WRAP53 Telomerase Cajal body protein 1 1 GDPPRLS(1)PDPVAGSAVSQELR;GDPPRLS(0.989)PDPVAGS(0.001)AVS(0.01)QELR 63.044 0.008457 12472800.0 18129.4 21669.4 44211.5 17730.6 29063.0 29333.1 23948.5 20986.5 40986.8 18695.9 True False 17870.87143147521 21619.225835663958 40576.601131325326 19034.567471547696 27353.57148005644 28078.591691795853 25188.43614908954 21961.609404984938 36370.434973861884 21927.461404279173 0.8149995615993963 0.9859429432832082 1.8504924205866689 0.8680698198758693 1.2474572854438295 1.2805217701268548 1.1487164740453715 1.0015573166485703 1.6586705730907887 1.0 14.42045117690283 -5.012765168741852 24.790197587272974 1.25164049618052 0.8577351034395754 0.21030945705072657 0.2847032523036889 733.0553100465698 1423628.232489068 0.06824448052129904 0.20334761148428335 9.710348822831594e-06 5.012765168741852 -0.3939053927409447 GDQCCYSHS(ph)PPTPR ddPTM_PC-9_AZD4547_30min_R2 2 GDQCCYSHSPPTPR 14 0 Q9NXH9-2;Q9NXH9 Q9NXH9-2 TRMT1 tRNA (guanine(26)-N(2))-dimethyltransferase 1 GDQCCYS(0.004)HS(0.982)PPT(0.014)PR;GDQCCYS(0.015)HS(0.979)PPT(0.006)PR 80.859 0.0062917 29260800.0 14827.0 11969.0 20077.8 25080.0 22635.1 19112.7 14834.2 20059.6 20042.4 21433.0 True False 19541.67757924134 15837.745183448136 19811.555253398532 19298.193482137372 19492.607075266318 17917.57984760747 16154.415062346767 16959.84974375078 21101.80034662944 20682.63719369747 0.9448349065077731 0.7657507616231022 0.9578834201779463 0.9330625152588389 0.9424623607093111 0.8663102137220402 0.7810616659305629 0.8200042182685912 1.0202664268103925 1.0 14.336132531531936 -8.274095928328192 24.46554381626322 1.0101332601791189 0.8760213710571131 0.39550943122972393 0.06612060577694516 696.4671526376491 1346277.0043526054 0.06502998718285012 0.01727374894155627 5.319907385041257e-09 8.274095928328192 -0.13411188912200578 GDQCCYSHS(ph)PPTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GDQCCYSHSPPTPR 14 0 Q9NXH9-2;Q9NXH9 Q9NXH9-2 TRMT1 tRNA (guanine(26)-N(2))-dimethyltransferase 1 GDQCCYSHS(0.962)PPT(0.038)PR;GDQCCYS(0.001)HS(0.968)PPT(0.03)PR 123.59 2.3283e-05 24192900.0 62499.0 54645.0 76751.0 62950.0 76689.0 71700.0 76310.0 68678.0 74712.0 61884.0 True False 73078.84628848251 60069.7944637762 78581.03491978833 59423.115586653636 61662.340966592776 67939.92577936375 69081.36436344324 66875.27527035584 75804.52165878234 73103.07932652548 0.9996685086556378 0.8217135997167202 1.0749346764011785 0.8128674760912833 0.8434985439008528 0.929371599736589 0.944985696907258 0.9148079107809911 1.0369538787851942 1.0 16.15764455775917 -8.254908262599178 23.63652000829563 1.0184769438700605 0.9150971809294669 0.21589682650792308 0.07666685564877802 323.01698522996753 1169042.0609706985 0.052715170087698146 0.018800831091431918 5.56021695092719e-09 8.254908262599178 -0.10337976294059359 GDQCCYSHS(ph)PPTPR ddPTM_PC-9_Lapatinib_30min_R1 6 GDQCCYSHSPPTPR 14 0 Q9NXH9-2;Q9NXH9 Q9NXH9-2 TRMT1 tRNA (guanine(26)-N(2))-dimethyltransferase 1 GDQCCYS(0.069)HS(0.59)PPT(0.342)PR;GDQCCYS(0.247)HS(0.753)PPTPR;GDQCCYS(0.009)HS(0.973)PPT(0.018)PR;GDQCCYS(0.003)HS(0.845)PPT(0.151)PR;GDQCCYS(0.002)HS(0.993)PPT(0.005)PR;GDQCCYS(0.003)HS(0.992)PPT(0.005)PR 111.77 0.00020854 58400600.0 94631.20000000001 94649.0 105452.9 89708.4 92063.79999999999 92378.8 97053.5 95398.6 114599.9 83106.1 True False 93281.74173476321 94429.84605571705 96782.9696219656 96305.85499444972 86648.78828839486 88427.9740695007 102078.45534357727 99831.16722571164 101692.45247155346 97470.87865308243 0.957021656353082 0.9688006034275222 0.9929424147948309 0.9880474694110509 0.8889710392043816 0.9072245504653019 1.0472713158449518 1.024215320568002 1.04331112919887 1.0 16.5726836291984 -7.274599273355883 24.98869398318321 1.0307173891983352 0.9521720324324742 0.5781913075085173 0.03268396124689109 648.5340169268416 1231465.5458621795 0.015164845517102343 0.010293612230704486 5.313745211925129e-08 7.274599273355883 -0.07854535676586105 GDQCCYSHSPPT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 GDQCCYSHSPPTPR 14 0 Q9NXH9-2;Q9NXH9 Q9NXH9-2 TRMT1 tRNA (guanine(26)-N(2))-dimethyltransferase 1 GDQCCYSHSPPT(1)PR 118.48 0.00024119999999999998 4685600.0 7907.3 10098.0 11924.0 15713.0 12966.0 12222.0 11661.0 15659.0 12025.0 11321.0 True False 10421.656917942613 13361.981022847294 11765.879968996807 12090.61061343001 11165.894709451388 11457.756407909852 12698.80640964971 13239.261358022779 12660.61695047595 10924.655235844222 0.9539575110570765 1.2231032224253733 1.077002405567225 1.1067269723771458 1.0220821132016733 1.0487979858912622 1.1623988249976465 1.2118699466674465 1.158903112011807 1.0 13.41530013091046 -7.270467224270171 24.521021530108108 1.1509488044746943 1.0783602428291132 0.09984496906326656 0.08244121723043901 997.0381573703661 2708096.713478333 0.03303126555649023 0.022628104684464773 5.364543555364544e-08 7.270467224270171 -0.07258856164558103 GDQCCYSHSPPT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GDQCCYSHSPPTPR 14 0 Q9NXH9-2;Q9NXH9 Q9NXH9-2 TRMT1 tRNA (guanine(26)-N(2))-dimethyltransferase 1 GDQCCYSHSPPT(1)PR;GDQCCYSHS(0.279)PPT(0.72)PR;GDQCCYSHS(0.002)PPT(0.998)PR;GDQCCYSHS(0.001)PPT(0.999)PR 112.01 0.00072318 21805700.0 43929.5 36738.6 48530.0 49401.1 52286.0 50533.3 50572.0 49238.6 48666.2 37781.7 True False 51365.896702825536 40385.76541105113 49687.13925104987 46633.31652752714 42040.93363819155 47883.244789209544 45781.45405042662 47946.13892260913 49377.85110759505 44631.22313022738 1.1508960118109997 0.904876957846559 1.11328204262003 1.0448585823305345 0.9419623906681261 1.0728642737281306 1.0257718888152143 1.0742734695553673 1.1063521822719873 1.0 15.445765724112183 -7.7614885100948054 24.999907318386896 1.067734623208266 1.0323607946049813 0.016933471357925445 0.07279082286647237 4.666625151523544 2368416.8448560466 0.03477199026663472 0.018351522937411942 1.731854848934848e-08 7.7614885100948054 -0.03537382860328475 GDQCCYSHSPPT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 GDQCCYSHSPPTPR 14 0 Q9NXH9-2;Q9NXH9 Q9NXH9-2 TRMT1 tRNA (guanine(26)-N(2))-dimethyltransferase 1 GDQCCYSHS(0.007)PPT(0.993)PR;GDQCCYSHSPPT(1)PR;GDQCCYSHS(0.001)PPT(0.999)PR;GDQCCYSHSPPT(1)PR 99.413 0.004638399999999999 11315900.0 37755.899999999994 29801.000000000004 39459.1 34370.5 34872.9 33099.9 30210.0 28175.899999999998 37839.0 31145.5 True False 37217.49394241591 29731.997615467986 36214.92511453079 36898.221226626854 32821.74458475933 31684.294436635515 31774.125981334757 29485.05517517999 33577.17335766536 36528.95817622993 1.0188490392434466 0.8139295260496958 0.9914031749773942 1.0101087758543634 0.8985130215434683 0.8673747081364361 0.8698338952905252 0.8071693430984972 0.9191932930492019 1.0 15.156752987467284 -6.5022779892941855 21.584173901636706 0.8796446720062577 0.9510516756079411 0.15315151790496084 0.07075586623870982 226.43809421029601 237247.53701883997 0.02165051435855037 0.024181897548415095 3.14573410398751e-07 6.5022779892941855 0.0714070036016834 GDQPAASGDS(ph)DDDEPPPLPR ddPTM_PC-9_AZD4547_30min_R2 2 GDQPAASGDSDDDEPPPLPR 20 0 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 GDQPAAS(0.334)GDS(0.666)DDDEPPPLPR;GDQPAAS(0.045)GDS(0.955)DDDEPPPLPR 252.55 1.5718999999999995e-137 22290000.0 23548.0 29544.0 37717.0 25437.0 31181.0 24260.0 33530.0 43705.0 37216.0 25454.0 True False 31035.774171172525 39093.52023559124 37216.847936149985 19572.892647732384 26852.056373237978 22743.018364906973 36514.105043783115 36951.396490988285 39183.16178203016 24562.863207594626 1.2635242849692103 1.591570164487333 1.5151673329615276 0.7968489863054977 1.0931973258286742 0.9259107202891163 1.4865573583658305 1.5043603092477928 1.5952196391304685 1.0 14.584191120006553 GDQPAASGDS(ph)DDDEPPPLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GDQPAASGDSDDDEPPPLPR 20 0 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 GDQPAAS(0.02)GDS(0.98)DDDEPPPLPR 236.6 2.7212e-44 15023000.0 27638.0 47369.0 39970.0 26046.0 38650.0 21331.0 27565.0 29690.0 26420.0 17024.0 True False 32316.567524617643 52071.48126918503 40923.03638706912 24586.72706227133 31076.809951346484 20212.364808920618 24953.843646682148 28910.668959155308 26806.3425182706 20110.31643809014 1.606964645439797 2.5892919899837348 2.0349275215559737 1.2225927492469786 1.5453168052833395 1.0050744288954694 1.240847886382239 1.4376038809810459 1.3329647298586405 1.0 14.295648162339987 -5.725160417370806 5.511501871225564 1.2729515270816638 2.142802803688734 0.6538656384051218 0.27324421545629274 0.10273077610606075 7.844016606184767 0.07174581893072624 0.12266776835699587 1.8829534457573978e-06 5.725160417370806 0.8698512766070701 GDQPAASGDS(ph)DDDEPPPLPR ddPTM_PC-9_Lapatinib_30min_R1 2 GDQPAASGDSDDDEPPPLPR 20 0 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 GDQPAAS(0.091)GDS(0.909)DDDEPPPLPR;GDQPAAS(0.006)GDS(0.994)DDDEPPPLPR 209.74 1.8981e-21 30561000.0 34726.0 81119.0 56602.0 41417.0 57007.0 52311.0 53532.0 57269.0 76856.0 39062.0 True False 34230.80087203151 80931.17393943643 51948.402050038494 44462.94434306179 53653.96034007421 50073.780472896884 56303.62502591235 59929.92681076323 68199.66795044084 45813.81465315675 0.7471720294671615 1.7665233631415138 1.133902567234904 0.9705139089525286 1.1711306021180066 1.0929843072879024 1.2289660979372914 1.3081191178790834 1.4886267049963198 1.0 15.48349507233482 -7.55186877576459 4.685450892670064 1.2961424881832837 1.166939190632 0.03343025071528505 0.2656864140650786 0.7356086290864944 39.65893627072317 0.12496761900947097 0.07220368481397572 2.806281441741254e-08 7.55186877576459 -0.1292032975512838 GDREEEVERPVS(ph)SPGDPEQK ddPTM_PC-9_Lapatinib_30min_R1 1 GDREEEVERPVSSPGDPEQK 20 2 O43149 O43149 ZZEF1 Zinc finger ZZ-type and EF-hand domain-containing protein 1 1 GDREEEVERPVS(0.5)S(0.5)PGDPEQK 79.935 0.004280699999999999 6531700.0 17603.0 21744.0 19295.0 16499.0 17195.0 19761.0 20264.0 18920.0 18108.0 16854.0 True False 17351.977992005155 21693.65310394737 17708.639580853895 17712.39149905054 16183.623906670693 18915.868095140915 21313.170767486507 19799.092270855796 16068.486354306518 19767.191443456653 0.8778170658001603 1.0974575303730574 0.8958601747501068 0.8960499800751263 0.8187113456640197 0.9569325085583898 1.0782093565720792 1.0016138270067547 0.8128866662858936 1.0 14.270820284585549 -6.992081461620045 24.9758142159896 0.9796346718473329 0.9211349973619126 0.0768574874894693 0.0911835805940552 525.7416264552238 1658229.2897523986 0.033444124472026555 0.02944697378027987 1.0184003464301297e-07 6.992081461620045 -0.05849967448542026 GDREEEVERPVSS(ph)PGDPEQK ddPTM_PC-9_Lapatinib_30min_R1 1 GDREEEVERPVSSPGDPEQK 20 2 O43149 O43149 ZZEF1 Zinc finger ZZ-type and EF-hand domain-containing protein 1 1 GDREEEVERPVS(0.297)S(0.703)PGDPEQK 68.445 0.014302 8671200.0 33637.0 37996.0 35093.0 31212.0 35550.0 36817.0 32895.0 38237.0 37951.0 27600.0 True False 33157.33021172966 37908.022596467286 32207.789002897433 33507.43460017976 33459.01889398914 35242.42273461883 34598.142143528865 40013.63061103132 33676.55873825311 32370.62322531169 1.024303115233284 1.1710624887452188 0.9949696914612712 1.0351186125443257 1.0336229445167553 1.0887162254899554 1.0688129759724676 1.2361093678216026 1.0403432304608908 1.0 14.982397521290887 -7.154750211647716 2.5588292742502134 1.107056301540485 1.0553204540072645 0.021563572225330452 0.07281591993910112 0.7529080855265324 9.608736724610724 0.03133718389945668 0.022607976597524906 7.002446321591151e-08 7.154750211647716 -0.05173584753322058 GDRS(ph)PEPGQTWTR ddPTM_PC-9_AZD4547_30min_R2 1 GDRSPEPGQTWTR 13 1 Q09666;E9PJZ0;E9PKR9;E9PJC6;E9PLK4;Q09666-2 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GDRS(1)PEPGQTWTR 136.33 0.00026474 14431000.0 13826.0 15308.0 17283.0 20051.0 21015.0 24070.0 19215.0 21687.0 12585.0 17682.0 True False 18222.380401334784 20256.011635744348 17053.816127488408 15428.551734861896 18097.42999530471 22564.899094942743 20925.09777561264 18335.772467682473 13250.217407213286 17062.958561981934 1.067949636936713 1.1871336123898744 0.9994641940633967 0.9042131631989269 1.060626733023175 1.3224493872486869 1.2263463982287315 1.0745951472059776 0.7765486482945674 1.0 14.058580198106922 -8.127089231882234 6.439233800506748 0.8913415706081017 1.1096893630199174 0.3392184947645398 0.12188711968263914 0.2901351363689262 13.691372855088145 0.09198505833759954 0.03411477184199085 7.462954058157445e-09 8.127089231882234 0.21834779241181568 GDRS(ph)PEPGQTWTR ddPTM_PC-9_Lapatinib_30min_R1 2 GDRSPEPGQTWTR 13 1 Q09666;E9PJZ0;E9PKR9;E9PJC6;E9PLK4;Q09666-2 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GDRS(0.986)PEPGQT(0.013)WT(0.001)R;GDRS(0.998)PEPGQT(0.002)WTR 104.9 0.0062155000000000005 22614000.0 51289.0 44304.0 51886.0 41447.0 45782.0 45434.0 47158.0 42051.0 54947.0 34874.0 True False 50557.609454749334 44201.41681002964 47620.13336575204 44495.150643138855 43089.19277087512 43490.89373182693 49599.610494133856 44004.84297472286 48758.29024243874 40901.92443331593 1.236069210806339 1.0806683896278035 1.1642516587059144 1.0878498080372994 1.053475927303254 1.0632970045879357 1.2126473553829507 1.075862409517326 1.192078145905613 1.0 15.319881103036433 GDRSEDFGVNEDLADSDAR ddPTM_PC-9_AZD4547_30min_R2 6 GDRSEDFGVNEDLADSDAR 19 1 P04083 P04083 ANXA1 Annexin A1 0 ;;;;; 210.02 7.249500000000001e-20 174537600.0 360786.0 345857.3 491755.0 701608.0 604268.0 537789.0 461736.0 516736.0 417088.0 538079.0 False True 475508.44318501087 457648.9086168743 485234.0073929914 539863.1153355442 520375.81862492504 504160.9688147125 502829.60949884425 436886.3246119971 439134.4201779719 519241.01798850164 0.9157759628218369 0.8813805010816937 0.9345063093681414 1.0397158480023996 1.002185498828308 0.9709575155826324 0.9683934667695671 0.8413940915231619 0.8457236715988726 1.0 18.986044829482616 -10.422446850489072 7.105541119049001 1.0000000009640193 0.9364303478789924 0.09353523575872946 0.061583912683072034 1.1040083071223314e-09 1.4081438240203848e-10 0.06714660677280694 0.016285444000039576 3.7805340112678906e-11 10.422446850489072 -0.06356965308502693 GDRSEDFGVNEDLADSDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GDRSEDFGVNEDLADSDAR 19 1 P04083 P04083 ANXA1 Annexin A1 0 252.12 1.4370999999999997e-136 0.0 8354.7 3990.2 5748.5 11483.0 9442.3 13270.0 10073.0 9342.6 9820.9 7103.2 False True 9768.985697153315 4386.320685686887 5885.566041307655 10839.644738388293 7592.149097117698 12574.097839500108 9118.81251779537 9097.36664930294 9964.512083182583 8390.953931099742 1.164228260263248 0.5227439837834986 0.7014179900921319 1.2918250806041094 0.9048016661107624 1.498530196059855 1.0867432466763922 1.0841874146853543 1.187530305255365 1.0 13.034619118382619 -5.755191146404282 24.997580247364652 1.1556298506781595 0.7687913918459119 0.3645075721705112 0.21344348699711888 143.50765353825673 574130.0631265048 0.05591434122236924 0.09384104286158435 1.7571500677680307e-06 5.755191146404282 -0.38683845883224754 GDRSEDFGVNEDLADSDAR ddPTM_PC-9_Lapatinib_30min_R1 5 GDRSEDFGVNEDLADSDAR 19 1 P04083 P04083 ANXA1 Annexin A1 0 ;;;; 301.75 1.9712999999999998e-121 100774000.0 296393.0 193583.5 259238.0 212254.0 207003.4 194824.0 181444.9 168100.5 221666.0 172662.0 False True 292166.3814681803 193135.2692994849 237924.45232761893 227863.8672185873 194827.8669963428 186491.83167692582 190839.22910528578 175911.0629110466 196699.6408335383 202506.39664234623 1.4427513713761138 0.9537242897101567 1.1748984539378566 1.1252181214849515 0.9620825328319641 0.9209182266291356 0.9423861777676769 0.8686691671361345 0.9713255684507416 1.0 17.627607954080688 -1.5228787452803612 0.5021166458818362 0.9386260347530486 14.184634198026382 0.6339791836733439 0.09763110562870464 73.52317130640762 0.7767070421723427 0.053988484942993485 1028.3390386561512 0.02999999999999837 1.5228787452803612 13.246008163273334 GDS(ph)ETDLEALFNAVMNPK ddPTM_PC-9_AZD4547_30min_R2 4 GDSETDLEALFNAVMNPK 18 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 GDS(0.939)ET(0.061)DLEALFNAVMNPK;GDS(0.852)ET(0.148)DLEALFNAVMNPK;GDS(0.698)ET(0.302)DLEALFNAVMNPK;GDS(0.72)ET(0.28)DLEALFNAVMNPK 149.19 3.3462e-12 38436110.0 49205.3 35896.9 45490.200000000004 46766.799999999996 41870.299999999996 44863.899999999994 41622.1 52021.5 41838.1 38907.1 True False 64851.56186617955 47499.87092286065 44886.97022523134 35985.43679985736 36057.33157898676 42058.55324078112 45326.38626730823 43982.77251014632 44049.576551826016 37544.97427139956 1.727303404109167 1.2651459175201616 1.195552030499716 0.958462151012041 0.9603770485589058 1.1202179268190322 1.2072557551820267 1.1714689745746039 1.1732482817382415 1.0 15.196332182655567 -4.6188556100003355 1.6455705402985241 1.0964926657587126 2.16540361854797 0.8219038232173922 0.08863680808581208 0.6906339299730568 1.3281163805542282 0.027434937682649728 1.3363485365573773 2.4051623120337427e-05 4.6188556100003355 1.0689109527892575 GDS(ph)ETDLEALFNAVMNPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GDSETDLEALFNAVMNPK 18 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 GDS(0.998)ET(0.002)DLEALFNAVMNPK;GDS(0.76)ET(0.24)DLEALFNAVMNPK;GDS(0.939)ET(0.061)DLEALFNAVMNPK;GDS(0.827)ET(0.173)DLEALFNAVMNPK 132.5 3.5323e-05 29729900.0 58238.6 47827.6 53224.8 55395.299999999996 55575.6 37347.5 32718.5 47573.5 41232.4 22810.1 True False 68097.24471521805 52575.608046403206 54493.881088178045 52291.68093498577 44685.960132782704 35388.93135348378 29619.166818573216 46324.7460332898 41835.345845962926 26945.390565347763 2.5272316817998655 1.9511911664036647 2.0223823052785184 1.9406540353597166 1.658389772618461 1.3133575209332669 1.0992294487898044 1.7192085570607472 1.552597493233737 1.0 14.717750877860212 -1.522878745577428 0.2302184799007359 1.1502368973621202 8.552524782970956 0.7611649207769902 0.21463357047284456 27.012837092201483 0.3537400527762449 0.3392776297549911 75.36959684417741 0.02999999997947772 1.522878745577428 7.402287885608835 up GDS(ph)ETDLEALFNAVMNPK ddPTM_PC-9_Lapatinib_30min_R1 4 GDSETDLEALFNAVMNPK 18 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 GDS(0.812)ET(0.188)DLEALFNAVMNPK;GDS(0.959)ET(0.041)DLEALFNAVMNPK;GDS(0.962)ET(0.038)DLEALFNAVMNPK;GDS(0.994)ET(0.006)DLEALFNAVMNPK 218.64 1.0496999999999999e-27 36580800.0 58520.4 81691.1 98593.2 85355.8 72403.4 68735.7 64924.9 75464.4 77592.0 60243.3 True False 57685.888364673 81501.94927703634 90487.24767675814 91633.15027060176 68144.7743625613 65796.03434174269 68286.39364202453 78970.75152033659 68852.7718800173 70656.27413584864 0.816429808537061 1.1534991092275126 1.2806682602988817 1.2968862481259842 0.9644546814277447 0.9312129056683442 0.966459022601905 1.117675004607545 0.9744749878494329 1.0 16.108530054231494 -6.29716519497057 24.882503409933097 0.9939088159516196 1.148329908728622 0.22467414452320134 0.13078666074364342 865.5129233267567 602814.7068898993 0.04285258298070927 0.048592501368109685 5.04469373285868e-07 6.29716519497057 0.15442109277700244 GDS(ph)LILEHQWELEK ddPTM_PC-9_AZD4547_30min_R2 2 GDSLILEHQWELEK 14 0 A0A087WWA3;Q4R9M9;O60333-2;O60333;O60333-4;A0A0U1RQL3 A0A087WWA3 KIF1B;KIF1Bbeta Kinesin-like protein;Kinesin-like protein KIF1B 1 GDS(1)LILEHQWELEK;GDS(1)LILEHQWELEK 116.96 7.7674e-05 6789400.0 26640.0 19385.5 22406.3 27441.0 23464.6 26381.3 25830.1 30125.5 24587.7 25047.3 True False 35110.96585357724 25651.48377088594 22109.177821983656 21114.90140922374 20206.945318478545 24731.673140565537 28128.928860465898 25470.29619012166 25887.355625215594 24170.401650804775 1.452643045028099 1.0612766863157135 0.9147211594329261 0.873585044811231 0.836020253631397 1.0232214382644351 1.1637758141900518 1.0537804277354077 1.071035392759129 1.0 14.560953826786566 -4.771447989667212 3.7598544254516137 0.9910153970808697 1.505537332901777 0.6891386590656546 0.0922618629089611 0.17235270351012144 4.275675969541212 0.026933316244295263 0.2514455582466951 1.6925909339715995e-05 4.771447989667212 0.5145219358209072 GDS(ph)LILEHQWELEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GDSLILEHQWELEK 14 0 A0A087WWA3;Q4R9M9;O60333-2;O60333;O60333-4;A0A0U1RQL3 A0A087WWA3 KIF1B;KIF1Bbeta Kinesin-like protein;Kinesin-like protein KIF1B 1 GDS(1)LILEHQWELEK 96.435 0.0016721 2703700.0 7830.7 10688.0 9038.2 8791.2 9452.9 8351.6 10713.0 7335.6 6489.4 6435.7 True False 9156.28284662506 11749.034005468755 9253.704965564375 8298.657565454956 7600.672103210432 7913.627393848462 9698.18708459663 7143.048272710667 6584.295198261366 7602.441465026827 1.2043871549352008 1.5454290650598643 1.2172017381697422 1.0915779626362005 0.9997672640000539 1.0409323676154785 1.2756674456765984 0.9395729392420203 0.8660764082894693 1.0 12.892247087935178 -5.632510603509168 2.852857136039572 1.0343664736532678 1.377594558014701 0.5459028962872179 0.12691276284049263 0.1942200284854288 3.162852200713381 0.03656093156512415 0.0717867310733318 2.3307162090279608e-06 5.632510603509168 0.34322808436143326 GDS(ph)LILEHQWELEK ddPTM_PC-9_Lapatinib_30min_R1 2 GDSLILEHQWELEK 14 0 A0A087WWA3;Q4R9M9;O60333-2;O60333;O60333-4;A0A0U1RQL3 A0A087WWA3 KIF1B;KIF1Bbeta Kinesin-like protein;Kinesin-like protein KIF1B 1 GDS(1)LILEHQWELEK;GDS(1)LILEHQWELEK 124.29 2.1868e-05 3647600.0 38296.3 33745.7 35907.3 34820.2 36089.0 36652.0 33890.1 34525.3 38503.0 34757.0 True False 37750.18773931871 33667.563904979645 32955.14040018631 37380.99366478211 33966.31597370393 35084.47939998504 35644.76355246716 36129.47147880433 34166.38668543539 40764.70113920865 0.9260508892339089 0.8258999321498085 0.808423451643783 0.9169941792809565 0.8332286273291026 0.8606583249604591 0.8744026708485545 0.8862930542634097 0.838136567437586 1.0 15.31503281768534 -10.918782002206152 2.92388125044474 1.0023542975595843 0.862240097223117 0.5555378377742398 0.03665826887297866 11219752.496796 13295139.144958446 221833.02453565845 0.009053572964115601 1.2056409702064493e-11 10.918782002206152 -0.14011420033646727 GDS(ph)LKEPTSIAESSR ddPTM_PC-9_AZD4547_30min_R2 2 GDSLKEPTSIAESSR 15 1 Q9C0B5;Q9C0B5-2;H0YEF4 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5;Palmitoyltransferase 1 GDS(1)LKEPTSIAESSR;GDS(0.766)LKEPT(0.231)S(0.003)IAESSR 180.56 0.00010088 33855000.0 33656.0 83526.0 47943.0 34746.0 48453.0 35664.0 58153.0 60606.0 48546.0 36268.0 True False 44357.90791171154 110524.14606004591 47307.24449460027 26735.846520348674 41726.13730965973 33433.92444212871 63328.504342711545 51240.73528733174 51112.042451376736 34998.26835912005 1.267431504226194 3.1579889875107177 1.3517024330797407 0.7639191243980988 1.1922343380393703 0.9553022480729766 1.8094753629777527 1.4640934448969427 1.4604163247996145 1.0 15.094995921849549 -5.484722780829218 24.33546467698731 1.2489633785228567 2.223244945779903 0.36683884043918924 0.507858097617298 383.3252736982979 244479.68031828068 0.12699506914693873 0.26424824547673526 3.2754970993242e-06 5.484722780829218 0.9742815672570464 GDS(ph)LKEPTSIAESSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GDSLKEPTSIAESSR 15 1 Q9C0B5;Q9C0B5-2;H0YEF4 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5;Palmitoyltransferase 1 GDS(1)LKEPTSIAESSR;GDS(1)LKEPTSIAESSR 135.55 0.00011201 20983000.0 50180.0 60191.0 40384.0 30033.0 82048.0 26917.0 36063.0 29400.0 26065.0 26484.0 True False 58674.48289982318 66166.3646915391 41346.90771717288 28350.348378299717 65971.28338649611 25505.425135329635 32646.851566490077 28628.2811518749 26446.151314864605 31285.339552771347 1.8754625565387422 2.1149319661348502 1.321606487518856 0.9061863730287805 2.1086964159432364 0.8152516641958674 1.0435191701027302 0.9150701753959043 0.8453208976765582 1.0 14.933199141839568 -4.404431000185367 0.3509543634050385 0.8610634062341217 3.2894284277008423 0.485972485329198 0.3620593347185541 7.345704438186979 0.5916983159746892 0.3418110289595566 7.967084659692823 3.940660310725127e-05 4.404431000185367 2.4283650214667207 GDS(ph)PKIDLAGSSLSGILDK ddPTM_PC-9_AZD4547_30min_R2 1 GDSPKIDLAGSSLSGILDK 19 1 Q5JPT2;Q96B97-2;Q96B97;Q96B97-3 Q5JPT2 SH3KBP1 SH3 domain-containing kinase-binding protein 1 1 GDS(0.999)PKIDLAGSSLSGILDK 106.44 0.00010446 5134200.0 28044.0 24565.0 20972.0 24706.0 26095.0 24412.0 22664.0 26116.0 22062.0 24569.0 True False 36961.40864856305 32505.155855242992 20693.897577138636 19010.413403894967 22472.15968248757 22885.513780878347 24681.05209401431 22080.372285977577 23228.152279534315 23708.846788221585 1.5589711713403647 1.3710137884644547 0.8728344217661081 0.8018278397808546 0.9478385803923457 0.9652731735669124 1.041006014104225 0.9313136350835494 0.979725099538537 1.0 14.53313787056947 -5.132800315793383 3.7025048973943604 0.9397438764125864 1.5245597138258724 0.9098910011185107 0.06673280134456097 0.06647303332804667 1.5867177816283355 0.019263549298108217 0.06212012114520173 7.365456758973766e-06 5.132800315793383 0.584815837413286 GDS(ph)PKIDLAGSSLSGILDKDLSDR ddPTM_PC-9_AZD4547_30min_R2 1 GDSPKIDLAGSSLSGILDKDLSDR 24 2 Q5JPT2;Q96B97-2;Q96B97;Q96B97-3 Q5JPT2 SH3KBP1 SH3 domain-containing kinase-binding protein 1 1 GDS(0.997)PKIDLAGS(0.001)S(0.001)LSGILDKDLSDR 48.146 0.012351 3282200.0 18230.0 7835.1 13720.0 21839.0 22194.0 16273.0 13375.0 12869.0 11558.0 17009.0 True False 24026.76079244416 10367.64285126865 13538.063835511253 16804.35595918652 19112.746196326083 15255.446737515715 14565.349089191732 10880.391750200852 12168.932283875347 16413.520087136672 1.4638396069149122 0.6316526129817701 0.8248117261647656 1.0238118252498527 1.1644513848863416 0.9294439374690537 0.8873994738402667 0.6628920361042997 0.7413968618110248 1.0 14.002597055796063 -7.399661300232921 2.9268372763007697 0.7775360806372541 0.9902201339807523 0.1446577844143262 0.21932204972331418 0.5258140160992086 8.638138853538331 0.10498226522478968 0.06470923122429595 3.98417769477993e-08 7.399661300232921 0.21268405334349816 GDSET(ph)DLEALFNAVMNPK ddPTM_PC-9_AZD4547_30min_R2 2 GDSETDLEALFNAVMNPK 18 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 GDS(0.294)ET(0.706)DLEALFNAVMNPK;GDS(0.433)ET(0.567)DLEALFNAVMNPK 137.32 0.00038752 8708100.0 31058.0 25081.0 31425.0 34784.0 26312.0 27666.0 26847.0 28905.0 27055.0 25548.0 True False 40933.79795346853 33187.942764313004 31008.283967269774 26765.086207442826 22659.032978180236 25936.040646476344 29236.330990469585 24438.396420821773 28485.072066122797 24653.572296206003 1.6603597021015868 1.3461717582169777 1.2577602789045592 1.085647381477522 0.9190973505152958 1.0520195748860177 1.1858861928487676 0.9912720204277519 1.1554135734928133 1.0 14.589509087435216 -4.814806794733384 1.0502539687567138 1.053445610466622 1.9305785423186004 0.8483735075819643 0.08020649865819798 0.645355724989016 0.5993301252622424 0.02686544882415158 0.6298419385031568 1.5317687504917877e-05 4.814806794733384 0.8771329318519783 GDSET(ph)DLEALFNAVMNPK ddPTM_PC-9_Lapatinib_30min_R1 2 GDSETDLEALFNAVMNPK 18 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 GDS(0.437)ET(0.563)DLEALFNAVMNPK;GDS(0.416)ET(0.584)DLEALFNAVMNPK 141.31 0.00016665 2471830.0 6417.3 8682.0 11519.7 9508.2 7242.2 7753.0 6563.200000000001 7840.4 8803.5 7695.599999999999 True False 6325.788125211307 8661.897362420492 10572.594733327944 10207.464746425381 6816.228034713028 7421.422263125723 6903.010382015767 8204.693606787405 7811.957125035207 9025.774206257563 0.7008582289623024 0.9596846945733701 1.1713781545740387 1.130924008640561 0.7551959398660052 0.8222477200881511 0.7648108876056211 0.9090293441086855 0.865516569162475 1.0 13.13983497240958 -6.270951987623603 24.936261568796034 0.8423244697813534 1.001399867925691 0.19693881544237113 0.13475398832012445 1012.1956721556094 2653355.185984853 0.04385688473770693 0.05037102454962813 5.358558944916889e-07 6.270951987623603 0.15907539814433758 GDT(ph)VSASPCSAPLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GDTVSASPCSAPLAR 15 0 Q15477 Q15477 SKIV2L Helicase SKI2W 1 GDT(0.693)VS(0.154)AS(0.154)PCSAPLAR 211.82 2.7654e-13 15216000.0 28025.0 23201.0 29684.0 35309.0 27875.0 31264.0 29012.0 24429.0 23702.0 22855.0 True False 32769.07898101924 25504.24194993269 30391.779137196903 33330.751203322536 22413.0938523618 29624.460802873473 26263.773331309363 23787.764634665025 24048.59691022141 26998.430579919543 1.2137401425619048 0.9446564634353903 1.125686881955324 1.234544026722529 0.8301628417257649 1.0972660323784553 0.9727888905825293 0.8810795340214148 0.8907405502343492 1.0 14.720587925330195 -6.261477776928226 24.99999999911958 0.9483624022764556 1.1161589891627954 0.44602588787232167 0.10014729302104859 3.739780471431941 2434967.0163957225 0.030647641418845028 0.037050482974724165 5.476741250112504e-07 6.261477776928226 0.1677965868863398 GDTGGEDTAAPGR ddPTM_PC-9_Lapatinib_30min_R1 1 GDTGGEDTAAPGR 13 0 Q9H773 Q9H773 DCTPP1 dCTP pyrophosphatase 1 0 123.01 0.00079757 3635200.0 9100.2 8823.8 11662.0 6996.0 9223.5 10120.0 10460.0 8965.5 9034.3 6299.9 False True 8970.429479227707 8803.369033232651 10703.195376621828 7510.509177971855 8680.9918640987 9687.191190872218 11001.567618826926 9382.069860166886 8016.761998603463 7388.82932091091 1.2140528749041146 1.1914430082067933 1.448564435820845 1.0164680833425916 1.1748805510408635 1.3110590013842627 1.488945967081918 1.269764052285653 1.0849840550404188 1.0 12.851130087909603 -8.389485000962855 3.5253864596082924 1.0060149723288576 1.2658328038213378 0.3324360770195085 0.12822232884563786 0.2811483564508515 6.037283266807259 0.12873696539818144 0.03428081628337497 4.078636477351004e-09 8.389485000962855 0.25981783149248017 GDTGGEDTAAPGRFS(ph)FSPEPTLEDIRR ddPTM_PC-9_AZD4547_30min_R2 1 GDTGGEDTAAPGRFSFSPEPTLEDIRR 27 2 Q9H773 Q9H773 DCTPP1 dCTP pyrophosphatase 1 1 GDTGGEDT(0.023)AAPGRFS(0.779)FS(0.182)PEPT(0.017)LEDIRR 63.536 0.00021432 6770700.0 19292.0 18310.0 31607.0 34592.0 35783.0 35871.0 24610.0 32986.0 24657.0 30181.0 True False 25426.45470147191 24228.349428434714 31187.870528353087 26617.3488410724 30815.14810954026 33627.98069940552 26800.242324112798 27888.771642872416 25960.318681736844 29124.372376381427 0.8730301334181414 0.8318925851972292 1.0708512487515462 0.9139200837391396 1.0580536367036009 1.1546336609360317 0.9201998236311044 0.9575750262515175 0.8913606221705059 1.0 14.82993933990046 -5.247658218803033 24.674316426675237 0.9965773053985995 0.8524613345523947 0.35251409713471893 0.07771300119878084 759.2761332641486 1359429.8193209367 0.020594770440846438 0.05384674863616933 5.6538174406548375e-06 5.247658218803033 -0.14411597084620476 GDTGGEDTAAPGRFS(ph)FSPEPTLEDIRR ddPTM_PC-9_Lapatinib_30min_R1 1 GDTGGEDTAAPGRFSFSPEPTLEDIRR 27 2 Q9H773 Q9H773 DCTPP1 dCTP pyrophosphatase 1 1 GDTGGEDT(0.004)AAPGRFS(0.801)FS(0.194)PEPT(0.001)LEDIRR 65.365 0.00012612 7026200.0 11147.0 11001.0 13477.0 10914.0 13190.0 9810.0 11070.0 10226.0 12160.0 9198.3 True False 10988.041735890558 10975.52786039943 12368.973082724435 11716.651968036715 12414.190132537748 9390.449168226924 11643.150434073998 10701.137291848381 10790.412749523262 10788.21389903567 1.0185227915135007 1.0173628334696352 1.146526496274797 1.086060406077417 1.1507178341771123 0.8704359457561655 1.0792472732779934 0.9919285427595134 1.0002038196969554 1.0 13.397168410983356 -6.73612422458912 24.999998599320637 0.9935387639201587 1.0837511267427993 0.3634249981684905 0.06299352240497225 273.2506562262588 269848.26598928607 0.020792177793531166 0.020784353011189995 1.83601309929174e-07 6.73612422458912 0.09021236282264056 GDTPGHAT(ph)PGHGGATSSAR ddPTM_PC-9_AZD4547_30min_R2 2 GDTPGHATPGHGGATSSAR 19 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 GDTPGHAT(1)PGHGGATSSAR;GDTPGHAT(1)PGHGGATSSAR 118.36 0.00011847 20388300.0 1795.23 2929.1299999999997 11024.7 11779.8 9662.4 10519.400000000001 7531.9 11882.6 7706.4 8649.5 True False 2366.0757968963007 3875.9139902409047 10878.50527458899 9064.149106095761 8320.94254516451 9861.620255061925 8202.224508776315 10046.4172049838 8113.744571072581 8346.683637702903 0.28347495839047643 0.46436574794005225 1.303332646447694 1.0859581481142986 0.9969160095607172 1.1815016218556416 0.9826926315651824 1.2036417864938609 0.9720920216050707 1.0 13.026987374485996 -5.154129666636124 4.966109022215833 1.092760653325171 0.3309051506774691 0.8769562765362876 0.10797644443510183 0.06274056119741717 2.3324760738770665 0.026275788936023347 0.07476188670182342 7.0124589725122745e-06 5.154129666636124 -0.7618555026477019 down GDTPGHAT(ph)PGHGGATSSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GDTPGHATPGHGGATSSAR 19 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 GDTPGHAT(0.97)PGHGGAT(0.003)S(0.013)S(0.013)AR 84.94 0.0027774 8283300.0 3473.6 5069.7 9801.6 8477.0 10006.0 7817.0 7878.2 7725.8 7295.3 5255.5 True False 4061.6118732727386 5572.986311519926 10035.307316775004 8002.061172804809 8045.39612867201 7407.062758957968 7131.919862771319 7523.005936161737 7401.97996114835 6208.28054748489 0.6542249246320201 0.8976698570391869 1.616439083256398 1.2889335640681732 1.295913750536189 1.1930940785140147 1.1487753828490588 1.2117696483947509 1.192275365865522 1.0 12.59997803795388 -5.03457777479983 7.66553614346152 1.2503790834115085 0.7116712997021156 0.6283147768913868 0.14903453468616162 0.12364303193426382 24.87586829738077 0.037908425034031426 0.10700052025596933 9.234687959607367e-06 5.03457777479983 -0.5387077837093929 GDTPGHAT(ph)PGHGGATSSAR ddPTM_PC-9_Lapatinib_30min_R1 2 GDTPGHATPGHGGATSSAR 19 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 GDT(0.002)PGHAT(0.914)PGHGGAT(0.012)S(0.036)S(0.036)AR;GDT(0.005)PGHAT(0.993)PGHGGATS(0.001)SAR 93.583 0.0016986 16821300.0 8156.6 8363.900000000001 17606.0 10838.1 15691.7 16814.1 12586.8 16670.199999999997 16539.0 9153.400000000001 True False 8040.285388262756 8344.533903426483 16158.50264112535 11635.170028841729 14768.745057069185 16095.00013858148 13238.482916314602 17444.758349557087 14676.20365660899 10735.552993861165 0.7489400306495971 0.7772803048150457 1.5051392928119447 1.0837979222397751 1.3756855436803574 1.4992241338461996 1.2331440144615438 1.6249520038262024 1.3670654567120277 1.0 13.390108886624404 -5.25113280109285 24.422570236419478 1.3529938815198004 0.7631100072361436 0.6124177564994903 0.18194570732499024 306.72307153803314 726808.7908013026 0.04442215071692108 0.11460198123751515 5.6087644174660735e-06 5.25113280109285 -0.5898838742836567 GDTPGHATPGHGGATSSAR ddPTM_PC-9_Lapatinib_30min_R1 2 GDTPGHATPGHGGATSSAR 19 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 0 ; 76.176 0.0016014 921170.0 1555.52 1791.52 4797.5 3171.68 4643.0 8612.3 3117.7 4271.8 5655.9 2099.0 False True 1533.3379995525675 1787.3718455106605 4403.068068885543 3404.9359276143177 4369.907868489214 8243.972005251855 3279.11925097674 4470.28342297261 5018.872982732619 2461.8093532583066 0.6228500178225138 0.7260399117198088 1.7885495735313135 1.3831030104373208 1.7750797244739767 3.348745098535196 1.331995609910528 1.8158528064149262 2.0386927915802793 1.0 11.265503326030148 -5.233309850425915 1.3212077565947387 1.9248971238056345 0.39753924920259426 0.35420740623372193 0.5991087720892948 0.7219045556285144 1.869508683185994 0.18659409609064248 1.191231185711763 5.843730103817098e-06 5.233309850425915 -1.5273578746030403 GDTSHS(ph)PTPGK ddPTM_PC-9_Lapatinib_30min_R1 1 GDTSHSPTPGK 11 0 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 GDT(0.001)S(0.004)HS(0.908)PT(0.087)PGK 65.495 0.025248 9508400.0 38017.0 56951.0 58781.0 49390.0 67098.0 39456.0 69464.0 60368.0 74637.0 52522.0 True False 37474.870608536046 56819.13345855903 53948.25308122167 53022.30536021008 63151.42755974356 37768.5588564283 73060.50603003765 63172.917664218934 66230.5950975468 61600.3577188341 0.6083547563081477 0.9223831737780116 0.8757782434878163 0.860746711930192 1.0251795589887496 0.6131223949837664 1.186040288329359 1.0255284222952497 1.0751657547160156 1.0 15.910651108354196 -7.279061375577151 24.998520366724442 1.0738109824116004 0.836399176537712 0.4772019775636641 0.12938629989913417 780.0275492282383 1106540.7515179373 0.052103410576960295 0.03521530603939963 5.259429335739243e-08 7.279061375577151 -0.23741180587388844 GDTVS(ph)ASPCSAPLAR ddPTM_PC-9_AZD4547_30min_R2 1 GDTVSASPCSAPLAR 15 0 Q15477 Q15477 SKIV2L Helicase SKI2W 1 GDT(0.19)VS(0.501)AS(0.307)PCS(0.002)APLAR 198.81 6.666799999999999e-10 19477000.0 34729.0 34242.0 40595.0 54429.0 46449.0 44318.0 44314.0 50849.0 37959.0 41105.0 True False 45772.09959192508 45310.056861194 40056.68377569822 41881.23496966725 40000.35811810174 41546.78845407862 48257.86015240695 42991.45544377672 39965.4352451656 39665.92646138824 1.153940010363321 1.1422916569287722 1.0098512085603333 1.0558491558349317 1.008431207500953 1.0474175737334979 1.2166074123941693 1.0838384295807544 1.007550782510246 1.0 15.275612625388833 -5.156118877562676 7.182813388489715 1.0608412008430181 1.1503541500819174 0.27331327786175585 0.060763964902606 0.3814283933955319 22.72395112145219 0.016468098031463183 0.04437341403966223 6.980413060764232e-06 5.156118877562676 0.0895129492388993 GDTVSAS(ph)PCSAPLAR ddPTM_PC-9_AZD4547_30min_R2 1 GDTVSASPCSAPLAR 15 0 Q15477 Q15477 SKIV2L Helicase SKI2W 1 GDTVS(0.011)AS(0.954)PCS(0.034)APLAR 85.976 0.0056222 20267000.0 29700.0 27003.0 42430.0 41069.0 40602.0 37754.0 29938.0 39856.0 32612.0 35365.0 True False 39143.98220162324 35731.19167755452 41867.35047673051 31601.176559724856 34965.11314153518 35393.23641173526 32602.42400240915 33697.170999767266 34335.80374128244 34126.88211426824 1.1470131396872432 1.0470101416799376 1.2268144021051963 0.9259907322888016 1.0245621918949483 1.0371072368470944 0.9553296985422021 0.9874084273780956 1.006121907835432 1.0 15.058620993114372 -5.768970532463215 24.999999245264963 0.9922486739618273 1.130952325078852 0.6454507281839306 0.05057606608861325 104.17494489080038 345814.2586060339 0.013649986958847981 0.02069607842690929 1.7022740063398946e-06 5.768970532463215 0.13870365111702476 GDTVSAS(ph)PCSAPLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GDTVSASPCSAPLAR 15 0 Q15477 Q15477 SKIV2L Helicase SKI2W 1 GDTVSAS(0.918)PCS(0.082)APLAR 103.14 0.001344 13433000.0 17681.0 21159.0 29559.0 20955.0 21119.0 21254.0 25539.0 15229.0 18218.0 16956.0 True False 20674.044084331887 23259.525685040564 30263.79866313177 19780.959287026628 16980.883554010004 20139.402824471366 23119.76103365195 14829.254886459286 18484.40378493013 20029.988576377862 1.032154561920898 1.1612350948852472 1.5109244095537346 0.9875671776645483 0.847773002428779 1.0054625217421511 1.1542573249850965 0.7403526382410421 0.922836461660767 1.0 14.289873977893894 -5.970422784011764 24.955020669899948 0.943066240144536 1.2310559920304345 0.43082400713866165 0.1500274443159503 192.71661543303208 162598.47555619653 0.04313760148678306 0.06398246022057628 1.070476692877236e-06 5.970422784011764 0.2879897518858985 GDTVSAS(ph)PCSAPLAR ddPTM_PC-9_Lapatinib_30min_R1 2 GDTVSASPCSAPLAR 15 0 Q15477 Q15477 SKIV2L Helicase SKI2W 1 GDT(0.001)VS(0.169)AS(0.828)PCS(0.001)APLAR;GDT(0.145)VS(0.192)AS(0.662)PCSAPLAR 192.54 3.1416e-08 33663000.0 50738.0 60805.0 64469.0 54122.0 62152.0 55982.0 57824.0 49669.0 63654.0 42081.0 True False 50014.46681579032 60664.209758348086 59168.60767753665 58102.312425699325 58496.341555533436 53587.780360415876 60817.84378499504 51976.8030655992 56484.616213664005 49354.644780592076 1.013368995727383 1.2291489489597809 1.1988457811939062 1.1772410212654825 1.1852246493836824 1.0857697507223962 1.23226180748262 1.0531289060363827 1.1444640411205163 1.0 15.590898243088258 -8.93450168176086 0.6342270935693574 0.9977079470182163 1.1638103118181313 0.28928179904111817 0.06995150172323626 1.7558209237003002 1.3033791954632175 0.07804388133844976 0.027201416089383517 1.1627820482403552e-09 8.93450168176086 0.16610236479991503 GDVEEDETIPDSEQDIRPR ddPTM_PC-9_Lapatinib_30min_R1 1 GDVEEDETIPDSEQDIRPR 19 1 Q92973-3;Q92973-2;Q92973 Q92973-3 TNPO1 Transportin-1 0 268.13 1.8274999999999996e-78 9689800.0 19278.0 31423.0 34852.0 24713.0 31730.0 29264.0 28174.0 35032.0 34323.0 24125.0 False True 19003.092184847785 31350.24197412338 31986.603092610527 26530.476460151294 29863.703783580197 28012.44693771586 29632.71186355927 36659.7146106036 30457.182302786758 28294.974105458128 0.671606629291174 1.1079791717524805 1.1304694244777655 0.9376391850110772 1.055441990237392 0.9900149345714451 1.047278281758282 1.2956263707458884 1.076416687616319 1.0 14.78825819666816 -7.535050483521808 24.642974124116023 1.1459034228777976 0.9978448587728597 0.16400598304587743 0.13845102434566167 324.28365895258946 656536.6578812739 0.06302537445442453 0.03642089003031741 2.917087904395742e-08 7.535050483521808 -0.1480585641049379 GDVEGSQS(ph)QDEGEGSGESER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GDVEGSQSQDEGEGSGESER 20 0 Q9UQE7 Q9UQE7 SMC3 Structural maintenance of chromosomes protein 3 1 GDVEGSQS(1)QDEGEGSGESER 218.42 1.2840999999999999e-28 1495600.0 1152.7 2943.6 969.7 2828.3 2542.0 2896.6 1100.0 1797.7 2544.2 2751.9 True False 1347.82934313723 3235.821154425321 992.8213256077286 2669.8395204723192 2043.9133478996837 2744.6971968271273 995.800036689656 1750.5122798205953 2581.4041118464806 3250.797685971585 0.41461495710841084 0.9953929672058973 0.30540852477289687 0.821287504908005 0.6287420951232796 0.8443149841872745 0.30632482636089836 0.5384869957840546 0.7940832869994373 1.0 11.66657805707675 -8.534647375424615 4.103684882080164 0.9993718797609203 0.6166604500490371 0.24466982980091745 0.21859019920276632 0.25751651760794636 13.863112018151902 0.19924120790125324 0.05216346721045614 2.919796775226313e-09 8.534647375424615 -0.3827114297118832 GDVEGSQSQDEGEGS(ph)GESER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GDVEGSQSQDEGEGSGESER 20 0 Q9UQE7 Q9UQE7 SMC3 Structural maintenance of chromosomes protein 3 1 GDVEGSQS(0.002)QDEGEGS(0.998)GESER 245.1 2.4899e-54 1757000.0 2093.7 3696.3 3530.5 2260.7 3074.6 3998.3 3649.1 3512.6 2332.9 2499.8 True False 2448.122057540053 4063.2442360043174 3614.680509495811 2134.040308288291 2472.154201200776 3788.622109395123 3303.4308308038408 3420.39797190734 2367.0142490868093 2952.9939515940887 0.8290305018127466 1.3759744525757975 1.2240731165549898 0.7226700573281875 0.837168731709137 1.2829765896912673 1.1186717226496785 1.158281401172846 0.8015642049686709 1.0 11.527962686168106 GDVMDVIEK ddPTM_PC-9_AZD4547_30min_R2 1 GDVMDVIEK 9 0 P16333-2;P16333 P16333-2 NCK1 Cytoplasmic protein NCK1 0 76.679 0.016396 6066500.0 33586.0 32942.0 39210.0 60576.0 50207.0 46554.0 43298.0 52838.0 40170.0 48133.0 False True 44265.64936780197 43589.857284079575 38690.04978064114 46611.139089870565 43236.62468590358 43642.971020605095 47151.438120659695 44673.101196449774 42293.30419131964 46447.87832054498 0.95301768279526 0.9384682112551687 0.8329777630236261 1.0035149241521624 0.9308632869626472 0.9396117239073284 1.0151472968315005 0.9617899204814662 0.9105540601757116 1.0 15.503325077205023 -5.793830315448214 24.999852960866956 0.9638273084813835 0.911185578064263 0.27156663472805975 0.04317786807478112 269.685782335072 208146.8114334238 0.012186135993691402 0.018076384280867705 1.6075692287138047e-06 5.793830315448214 -0.0526417304171205 GDVSVQEHER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GDVSVQEHER 10 0 Q9P232 Q9P232 CNTN3 Contactin-3 0 75.387 0.020627 8166800.0 47375.0 59659.0 61034.0 54422.0 62661.0 50658.0 63146.0 51258.0 46294.0 42237.0 False True 55394.65180109857 65581.5512474046 62489.28203273398 51372.911778504604 50383.026865752196 48001.405301687744 57164.35374255002 49912.531812340254 46970.96217035651 49894.233752091954 1.1102415576985585 1.3144114322560352 1.2524349475577214 1.0296362508292984 1.0097965852344561 0.9620631822945903 1.1457106251311704 1.0003667369728377 0.941410632814601 1.0 15.606585473309373 -5.777845269023443 8.29665101252734 1.0157333207690475 1.234761220881098 0.6635226985701658 0.06939557225714205 0.09423921759224493 35.98346324841895 0.019390350713790656 0.029877319206188677 1.6678413272850948e-06 5.777845269023443 0.21902790011205053 GDVT(ph)AEEAAGASPAK ddPTM_PC-9_AZD4547_30min_R2 1 GDVTAEEAAGASPAK 15 0 P49006 P49006 MARCKSL1 MARCKS-related protein 1 GDVT(0.976)AEEAAGAS(0.024)PAK 140.03 0.00016381 4840000.0 39046.0 45391.0 59938.0 79971.0 73754.0 66462.0 50865.0 68567.0 62567.0 59321.0 True False 51461.81579274684 60062.75308061612 59143.18295720649 61534.92148963346 63514.53018670971 62306.12063348908 55391.88646143834 57971.54566291253 65874.163886938 57244.189845907145 0.8989875816440831 1.0492375425749956 1.0331735520480096 1.0749548845966084 1.1095367120694937 1.0884269792481631 0.9676420718075506 1.0127061946192848 1.1507572046047199 1.0 15.804841649949017 -4.75987094631201 5.641185030911842 1.054996941010293 0.8917782991836324 0.4490291416240183 0.05155751536731346 0.14277305278037486 15.166274351697174 0.013111784343238285 0.09082150927582666 1.738317305334369e-05 4.75987094631201 -0.16321864182666068 GDVT(ph)AEEAAGASPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GDVTAEEAAGASPAK 15 0 P49006 P49006 MARCKSL1 MARCKS-related protein 1 GDVT(0.985)AEEAAGAS(0.015)PAK;GDVT(1)AEEAAGASPAK 132.23 1.7804e-05 3557000.0 34463.0 54246.0 40000.0 44200.0 53216.0 36260.0 46102.0 47955.0 41189.0 37410.0 True False 40296.90522472317 59631.18438067535 40953.75170084474 41723.617298333455 42788.70681425239 34358.46176791813 41734.88481042412 46696.232062522475 41791.31120306767 44192.136862602936 0.911856906806965 1.3493618687431592 0.9267203309985528 0.944141203853882 0.968242539329702 0.7774790767584169 0.9443961703001912 1.0566638179933454 0.9456730126673976 1.0 15.431502072276986 GDVT(ph)AEEAAGASPAK ddPTM_PC-9_Lapatinib_30min_R1 2 GDVTAEEAAGASPAK 15 0 P49006 P49006 MARCKSL1 MARCKS-related protein 1 GDVT(0.972)AEEAAGAS(0.028)PAK;GDVT(1)AEEAAGASPAK 124.92 6.814e-05 9608400.0 58290.0 68701.0 73912.0 69372.0 79125.0 76274.0 63593.0 64392.0 76171.0 67112.0 True False 57458.773910923155 68541.92705547686 67835.24066857084 74473.84829820794 74471.02306573535 73011.9388233782 66885.53437706137 67383.88739455318 67591.8198638106 78712.219778881 0.7299854339305486 0.8707914380769007 0.8618133354533024 0.9461535770102848 0.9461176838226637 0.9275807368726726 0.8497477845874091 0.8560791143211123 0.85872079397189 1.0 16.264300005699887 -4.383305559195333 1.4714056931031152 0.9033510498960713 0.4508151053697865 0.556070008195064 0.04713722872754047 2.673861522946039 2.4577682723699437 0.01386081174482526 2.3595484342660478 4.137084970094426e-05 4.383305559195333 -0.4525359445262848 GDVTAEEAAGAS(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 6 GDVTAEEAAGASPAK 15 0 P49006 P49006 MARCKSL1 MARCKS-related protein 1 GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK 165.58 9.176399999999999e-06 359423100.0 426514.0 458952.0 452096.0 449901.0 407970.0 492593.0 494463.0 518233.0 441389.0 424654.0 True False 562136.5799576826 607299.2587044769 446100.91164572106 346183.2753511598 351330.4075748023 461791.08183943166 538469.2490982452 438151.9976596352 464719.92142649717 409786.9927146183 1.371777508685257 1.4819876411436248 1.088616572943281 0.8447883449347231 0.8573488515275398 1.1269051728077417 1.3140223059086775 1.0692189001830292 1.1340523971929364 1.0 18.64451466609701 -5.296671470890117 6.788633175553915 1.053270974152609 1.4270613677211808 0.5637541262127881 0.13114001191917302 0.15008473436607303 22.705076207824902 0.03881781437358058 0.08386752818311806 5.050432012236429e-06 5.296671470890117 0.3737903935685718 GDVTAEEAAGAS(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 GDVTAEEAAGASPAK 15 0 P49006 P49006 MARCKSL1 MARCKS-related protein 1 GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK 176.25 2.1878000000000003e-05 463107400.0 684062.0 855190.0 681307.0 612663.0 711086.0 518890.0 724048.0 475551.0 502915.0 436159.0 True False 799860.1857596434 940087.6114461831 697551.9427511856 578337.478390245 571753.8028735629 491678.49494636094 655460.9317864307 463068.29013793333 510269.18045329594 515231.1740672552 1.5524297170249144 1.8245938110170903 1.3538620678649607 1.1224815335314944 1.109703433431863 0.9542871621393393 1.2721686201791638 0.8987582922874289 0.9903693839509183 1.0 18.97486036080784 -5.569517494141679 2.3722851699277885 1.046707140849387 1.691188751887421 0.8253695508988858 0.1175904894216323 0.10858047464083853 1.2202148423008272 0.03287600505401442 0.07365141633837935 2.6945267899102477e-06 5.569517494141679 0.6444816110380338 GDVTAEEAAGAS(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 6 GDVTAEEAAGASPAK 15 0 P49006 P49006 MARCKSL1 MARCKS-related protein 1 GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK 183.76 5.2164e-07 529857000.0 456969.0 671054.0 524992.0 496495.0 610921.0 495085.0 502942.0 536102.0 466964.0 448526.0 True False 450452.53826214845 669500.2156924335 481829.1842877244 533008.8985587673 574987.8278968979 473911.36864950304 528981.8758458945 561011.2560565717 414369.596971084 526053.1214766718 0.8562871692457472 1.272685567976661 0.9159325638733834 1.0132225754360513 1.0930223667960806 0.9008812024899637 1.005567411825257 1.066453620656731 0.7876953487281219 1.0 19.00484896639037 -7.198782186779581 0.7469745672809376 0.9406234024062656 1.0372148644335892 0.05633294964639357 0.12646157400925478 2.006996022939009 2.2360473537853225 0.09951682261964566 0.0657036836252824 6.327291066397056e-08 7.198782186779581 0.0965914620273236 GDVTAEEAAGAS(ph)PAKANGQENGHVK ddPTM_PC-9_AZD4547_30min_R2 4 GDVTAEEAAGASPAKANGQENGHVK 25 1 P49006 P49006 MARCKSL1 MARCKS-related protein 1 GDVTAEEAAGAS(1)PAKANGQENGHVK;GDVT(0.002)AEEAAGAS(0.998)PAKANGQENGHVK;GDVTAEEAAGAS(1)PAKANGQENGHVK;GDVT(0.015)AEEAAGAS(0.985)PAKANGQENGHVK 58.5 0.0020556 157107000.0 261062.0 177034.0 239812.0 390364.0 350876.0 266060.0 231385.0 303814.0 229010.0 291654.0 True False 344074.28557306936 234256.77841144268 236631.936189623 300371.6108636788 302162.9239606245 249423.22614044315 251977.8167478597 256866.52725118637 241115.00106681886 281443.2822325693 1.2225350800476567 0.8323409837789829 0.8407801895732702 1.0672545049963855 1.0736192442175032 0.8862290979620309 0.8953058490116635 0.9126759935912272 0.8567090290951576 1.0 18.102484687377228 -6.793926772176176 24.98828572399471 0.9037963159565516 0.9916648411283784 0.14972453323979296 0.11216665630092958 433.295358328358 333274.28038017603 0.040317150184200026 0.03555894658486363 1.6072122275175795e-07 6.793926772176176 0.08786852517182675 GDVTAEEAAGAS(ph)PAKANGQENGHVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 GDVTAEEAAGASPAKANGQENGHVK 25 1 P49006 P49006 MARCKSL1 MARCKS-related protein 1 GDVTAEEAAGAS(1)PAKANGQENGHVK;GDVT(0.006)AEEAAGAS(0.994)PAKANGQENGHVK;GDVTAEEAAGAS(1)PAKANGQENGHVK;GDVT(0.003)AEEAAGAS(0.997)PAKANGQENGHVK;GDVT(0.007)AEEAAGAS(0.993)PAKANGQENGHVK;GDVTAEEAAGAS(1)PAKANGQENGHVK;GDVT(0.002)AEEAAGAS(0.998)PAKANGQENGHVK 68.676 0.00025462 112149000.0 312925.7 154676.9 222875.1 352181.6 366702.3 392102.7 306803.9 385417.7 360269.0 300146.3 True False 365897.8404457002 170032.20040798033 228189.28764252362 332450.00674015214 294849.61670948693 371540.1441546461 277741.2135241182 375300.89375880786 365537.2525630143 354560.44823319605 1.0319759078289734 0.4795577207081749 0.6435835942209844 0.9376398535053132 0.8315919561212958 1.047889424796424 0.7833395261883427 1.0584962187095688 1.0309589080917416 1.0 18.435672084784137 -5.7706633653946495 23.701397813197076 0.9496277912374599 0.6944909400909306 0.33101553291975505 0.15332048516580482 104.34918336373308 268130.5283248324 0.041831548397730636 0.06312478768325959 1.6956516413413453e-06 5.7706633653946495 -0.2551368511465293 GDVTAEEAAGAS(ph)PAKANGQENGHVK ddPTM_PC-9_Lapatinib_30min_R1 4 GDVTAEEAAGASPAKANGQENGHVK 25 1 P49006 P49006 MARCKSL1 MARCKS-related protein 1 GDVTAEEAAGAS(1)PAKANGQENGHVK;GDVT(0.002)AEEAAGAS(0.998)PAKANGQENGHVK;GDVTAEEAAGAS(1)PAKANGQENGHVK;GDVTAEEAAGAS(1)PAKANGQENGHVK 64.028 0.00046959 165545800.0 1018662.0 435040.0 449650.0 429821.0 386570.0 385605.0 266318.0 255696.0 436606.0 280853.0 True False 1004135.6930802703 434032.6916087772 412681.51269919495 461431.47018082236 363832.71262586163 369113.57303915836 280106.64293601783 267576.5696241406 387430.8346149963 329398.06683690136 3.048395829163926 1.3176540341497656 1.2528352599699095 1.400832356460963 1.1045380931334072 1.1205699431803946 0.8503590978107053 0.8123197934753785 1.1761782281704445 1.0 18.329472562673516 -2.8879644283536576 1.2205782546788684 1.0567767590993133 199.9999999911728 0.9190521124829694 0.17270298220765204 41.38337901439526 0.8113339099336286 0.05552927029223736 22335.968810522943 0.001294301849156961 2.8879644283536576 198.9432232320735 up GDVTITNDGATILK ddPTM_PC-9_Lapatinib_30min_R1 1 GDVTITNDGATILK 14 0 P50991 P50991 CCT4 T-complex protein 1 subunit delta 0 123.64 0.0014069 0.0 13435.0 10952.0 13292.0 13660.0 11017.0 12370.0 14898.0 12082.0 16222.0 12405.0 False True 13243.414436322751 10926.64131688888 12199.183068603785 14664.601968424178 10369.001720255375 11840.963935878397 15669.345543526146 12643.373827509497 14394.907534766973 14549.18772137651 0.9102511212268407 0.7510138384450717 0.8384786355241014 1.0079326935123736 0.7126859532522656 0.8138573893359673 1.076991090059539 0.8690089144243509 0.9893959587597555 1.0 13.828650989517786 -7.237543134173489 24.935671694834884 0.9729330795675141 0.8369440825894662 0.38202077825709635 0.08977885201268879 858.4021136300848 895741.7342485645 0.03412465168793904 0.02641959261526039 5.787045085022402e-08 7.237543134173489 -0.1359889969780479 GDYDAFFEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GDYDAFFEAR 10 0 O75368 O75368 SH3BGRL SH3 domain-binding glutamic acid-rich-like protein 0 ; 96.03399999999999 0.026202 1394200.0 15460.7 17973.9 27946.0 19946.2 24442.0 21547.0 18804.9 17511.1 17801.2 15294.5 False True 18077.891147255825 19758.230006633134 28612.338625795186 18828.679080452897 19652.765558365085 20417.03738867435 17023.563736313918 17051.452179544096 18061.50887343824 18067.27177880461 1.000587768235361 1.093592339149525 1.5836557381818646 1.042142904084806 1.087755019073797 1.1300564710952286 0.9422321169865222 0.9437757060558413 0.9996810306815038 1.0 14.141091050204187 -6.81447784265089 1.2755132732006549 0.9678253388631936 1.197138506515558 0.2557077180169718 0.15299480095118048 0.6191662227040562 2.110424707715857 0.08014746572958133 0.06883505637594885 1.5329294131722537e-07 6.81447784265089 0.22931316765236442 GDYPLEAVR ddPTM_PC-9_AZD4547_30min_R2 2 GDYPLEAVR 9 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ; 111.17 0.010381 59760000.0 65584.0 62514.0 96283.0 103845.0 79749.0 88556.0 86705.0 96225.0 76488.0 71993.0 False True 86438.3477680557 82720.427972101 95006.22450980538 79905.1396392566 68677.22791794223 83018.5793208038 94421.57703015849 81355.637280525 80530.99952665312 69472.54698296389 1.2442087057676492 1.190692317533511 1.3675362230940358 1.1501685645532902 0.9885520381854334 1.1949839602276517 1.3591207049500087 1.1710472814603312 1.1591773013072486 1.0 16.08415536952957 -8.723947140490809 2.06248494889943 1.0004378141210475 1.208051648034661 0.27672176455594355 0.10138178692552578 1.1361708120929195 8.565705608317339 0.1042082909979707 0.028766409969153528 1.88822115715022e-09 8.723947140490809 0.20761383391361354 GDYPLEAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GDYPLEAVR 9 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 104.06 0.012572 15281000.0 29439.0 30303.0 40045.0 36572.0 38932.0 31282.0 40441.0 26898.0 29141.0 27946.0 False True 34422.44125324622 33311.281574449815 40999.82467150822 34522.989408023765 31303.55407570043 29641.516851186283 36610.13571251491 26191.95600078679 29567.131995644326 33012.38857958572 1.0427128340096075 1.0090539645183059 1.2419526861155932 1.045758604373516 0.9482365688333741 0.8978907048705974 1.1089817273977556 0.793397785732579 0.895637464231477 1.0 15.010719906696822 -6.185304572552636 3.879813774090338 0.9360244281994239 1.0956071154288285 0.3628498132428779 0.09480763031248135 0.25964044828856725 7.5176197832189215 0.02936720234262085 0.0382527499495201 6.52672670011338e-07 6.185304572552636 0.1595826872294046 GDYPLEAVR ddPTM_PC-9_Lapatinib_30min_R1 2 GDYPLEAVR 9 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ; 145.16 0.0023445000000000002 76011100.0 67841.0 72537.0 77085.0 73582.0 76077.0 76990.0 72378.0 68349.0 70399.0 80844.0 False True 66873.57489948432 72369.04503315983 70747.36885670488 78993.46574235623 71602.30043313678 73697.31717245573 76125.3786917262 71524.74406029203 62469.92328566521 94817.77768214126 0.7052851958170269 0.7632434212470516 0.746140339777548 0.8331081752112662 0.7551569144888632 0.7772521037089912 0.8028597648314665 0.7543389626791851 0.6588418840091766 1.0 16.53286995944643 -11.156291354799091 3.105604868394092 1.017473691699391 0.7594347049378019 0.7200302496932907 0.04573573416237438 63000174.09640967 71384122.14391294 8930099.639303556 0.011512361158490797 6.977641385408824e-12 11.156291354799091 -0.2580389867615891 GEAAAERPGEAAVAS(ph)SPSK ddPTM_PC-9_AZD4547_30min_R2 3 GEAAAERPGEAAVASSPSK 19 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 GEAAAERPGEAAVAS(0.74)S(0.254)PS(0.005)K;GEAAAERPGEAAVAS(0.978)S(0.019)PS(0.003)K;GEAAAERPGEAAVAS(0.984)S(0.015)PSK 208.4 6.1314e-20 130382000.0 83638.0 109270.0 89613.0 69157.0 73438.0 100311.0 106206.0 116244.0 110632.0 90175.0 True False 110233.14422152739 144589.39060868724 88424.67306790588 53213.922114998975 63242.401332152665 94038.53731253844 115658.12825171546 98281.16082138057 116479.78166029575 87018.00069713377 1.2667855310212648 1.661603225198551 1.0161653032648732 0.6115277493010909 0.7267737804304181 1.0806791302852343 1.329128770198521 1.129434829966368 1.3385711085882532 1.0 16.40902624982406 -7.0252387610963005 23.19004900624378 1.2093320034624382 1.0472658758677305 0.05413992110032817 0.28291462658702793 1068.659998051839 981909.2658297928 0.1229759555948778 0.0957901567058639 9.43542004712975e-08 7.0252387610963005 -0.16206612759470773 GEAAAERPGEAAVAS(ph)SPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GEAAAERPGEAAVASSPSK 19 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 GEAAAERPGEAAVAS(0.594)S(0.393)PS(0.013)K;GEAAAERPGEAAVAS(0.758)S(0.241)PS(0.001)K;GEAAAERPGEAAVAS(0.575)S(0.371)PS(0.054)K;GEAAAERPGEAAVAS(0.802)S(0.068)PS(0.13)K 136.33 0.00028892 592227500.0 287667.0 468983.0 364919.0 326462.0 316350.0 162283.0 306896.0 211746.0 215028.0 239346.0 True False 336363.3414177654 515540.5328393294 373620.05292301474 308171.3925440838 254363.48843747695 153772.59379710592 277824.58914537146 206187.8918634321 218172.3777069907 282737.53513810696 1.1896663853048879 1.8233890756227562 1.3214377522974265 1.0899557159736621 0.8996452781312876 0.5438704617764798 0.9826236513297192 0.729255462182327 0.771642780292406 1.0 18.109103896915975 -5.89720001412283 1.9024184551098307 0.7999620153615326 1.5147891566434812 0.6842625303408161 0.19112044920915155 0.17278038027063589 1.2724583216401186 0.057989006486104416 0.10238561405660215 1.2670681837947354e-06 5.89720001412283 0.7148271412819487 GEAAAERPGEAAVAS(ph)SPSK ddPTM_PC-9_Lapatinib_30min_R1 3 GEAAAERPGEAAVASSPSK 19 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 GEAAAERPGEAAVAS(0.978)S(0.022)PSK;GEAAAERPGEAAVAS(0.986)S(0.013)PS(0.002)K;GEAAAERPGEAAVAS(0.59)S(0.399)PS(0.011)K 216.16 4.4054e-27 151934000.0 87733.0 195689.0 158424.0 156474.0 205901.0 175612.0 184271.0 210979.0 166854.0 156042.0 True False 86481.91133173814 195235.8941435965 145398.99025432472 167981.61994196204 193790.3079969414 168101.48413156645 193811.65073507212 220781.85455670606 148061.14546948645 183013.6517871043 0.4725434987349503 1.066783227574247 0.7944707339289865 0.9178638768290975 1.0588844389727459 0.9185188235417278 1.059001057257351 1.2063682266366482 0.809016945040377 1.0 17.48159174388031 -4.755655399128196 24.963519855803433 0.9827446717610887 0.472542661104646 0.6196210715757435 0.11955875709585752 123.53938635793332 533138.0778106088 0.029671920383745956 0.25792911398201857 1.7552727106347066e-05 4.755655399128196 -0.5102020106564427 GEAAAERPGEAAVAS(ph)SPSKANGQENGHVK ddPTM_PC-9_AZD4547_30min_R2 1 GEAAAERPGEAAVASSPSKANGQENGHVK 29 2 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 GEAAAERPGEAAVAS(0.333)S(0.333)PS(0.333)KANGQENGHVK 74.819 1.8512e-06 58927000.0 56289.0 42190.0 62271.0 67139.0 73304.0 73761.0 57624.0 73266.0 60145.0 68672.0 True False 74187.73111606634 55827.092429582786 61445.245852851396 51661.14083720973 63127.0049191443 69148.71300964142 62752.424367520354 61944.42318519035 63324.14191154888 66267.81418212995 1.1195137795275598 0.8424465650269984 0.9272260842039509 0.7795811809217768 0.9526043026807332 1.0434735755670714 0.9469517765449766 0.9347588108903483 0.9555791554782431 1.0 16.016020713018285 -6.508893363741101 24.64036609499883 0.9733376956233315 0.9067600632844371 0.08917038901367691 0.08609502245534476 1239.3113663230158 2183503.863617447 0.02688040085167444 0.029287388853870416 3.098179930018553e-07 6.508893363741101 -0.06657763233889435 GEAAAERPGEAAVAS(ph)SPSKANGQENGHVK ddPTM_PC-9_Lapatinib_30min_R1 1 GEAAAERPGEAAVASSPSKANGQENGHVK 29 2 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 GEAAAERPGEAAVAS(0.431)S(0.431)PS(0.139)KANGQENGHVK 65.741 6.5637e-05 61412000.0 47488.0 36687.0 39436.0 30017.0 34551.0 36064.0 27053.0 27355.0 37985.0 27776.0 True False 46810.812411767336 36602.05350554256 36193.72430736223 32224.55031377658 32518.778109879568 34521.6267892901 28453.671968654395 28626.013164337204 33706.729300217215 32577.044590806425 1.4369263080720902 1.1235535317980327 1.1110192702249138 0.9891796729427899 0.9982114252026625 1.0596917928838903 0.8734270504293785 0.8787173153336247 1.0346773233606832 1.0 14.991568107182472 -1.522878763855625 0.6405835411819152 0.9590554644142087 39.72885943137646 0.8356955564525999 0.061281943397838635 79.11350302378393 0.5291346268206925 0.02650801692257104 4340.082604141785 0.029999998716864634 1.522878763855625 38.76980396696226 GEAAAERPGEAAVASS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GEAAAERPGEAAVASSPSK 19 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 GEAAAERPGEAAVAS(0.258)S(0.737)PS(0.005)K 102.15 0.00016868 464320000.0 111690.0 168320.0 145630.0 109770.0 135950.0 77790.0 125810.0 89660.0 83930.0 87501.0 True False 130596.91102194635 185029.69721187337 149102.37150485077 103619.94277914162 109311.57342524055 73710.5554585315 113892.36601447797 87306.52000262271 85157.31747003982 103364.23864246493 1.2634631932391893 1.7900745909993863 1.442494749277777 1.0024738162834166 1.05753764416867 0.7131146751198449 1.1018546405438117 0.8446491857267426 0.8238566702416052 1.0 16.65737761118232 -5.758587334128262 3.2490575200725114 0.921915510319037 1.548868096364732 0.7250058285417111 0.16013727414555723 0.1127024820522305 2.466801495544435 0.04397006620370841 0.07608039080723077 1.7434627218625062e-06 5.758587334128262 0.6269525860456951 GEAAAERPGEAAVASS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 1 GEAAAERPGEAAVASSPSK 19 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 GEAAAERPGEAAVAS(0.11)S(0.888)PS(0.003)K 111.25 6.1499e-05 9128200.0 10639.0 30975.0 20176.0 21166.0 28681.0 23935.0 24002.0 23152.0 19995.0 22611.0 True False 10487.285909046348 30903.279290598315 18517.207161612238 22722.618247706145 26994.039969015543 22911.355845210135 25244.706117312042 24227.72644053136 17742.952543315616 26519.281222736347 0.3954589048233727 1.1653136082777138 0.6982544891049491 0.8568338657770586 1.0179023987223363 0.8639508609896654 0.951937795948574 0.9135891066217768 0.6690585764482813 1.0 14.694754052796076 -4.74069645666882 24.9525437725185 0.8972809373083317 0.3954570328418319 0.5442336886089971 0.1395132638284742 1168.6414384715763 1405734.5527720912 0.03282554295966638 1.4284870414945101 1.8167850325832242e-05 4.74069645666882 -0.5018239044664998 GEAAAERPGEAAVASS(ph)PSKANGQENGHVK ddPTM_PC-9_AZD4547_30min_R2 1 GEAAAERPGEAAVASSPSKANGQENGHVK 29 2 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 GEAAAERPGEAAVAS(0.036)S(0.482)PS(0.482)KANGQENGHVK 55.417 0.00077157 24357000.0 6537.6 6297.6 11670.0 8027.8 9518.8 10554.0 10853.0 11222.0 7243.4 11748.0 True False 8616.420809472462 8333.176043719859 11515.248174957458 6177.1147382736235 8197.278926448078 9894.056711592253 11818.895974953113 9487.897755905968 7626.271336305815 11336.7060958129 0.7600462371212791 0.7350614872866498 1.0157490260076956 0.5448773820250205 0.7230741325715113 0.8727452778586652 1.0425335079753284 0.8369183849099014 0.6727060992718601 1.0 13.468713902586616 -6.807766149611611 7.909153924490341 0.8851890041455601 0.757416600966358 0.173350873311783 0.14111611332399673 0.48064045491972823 71.0468698138137 0.050956570759907886 0.045199857184765616 1.556803683118457e-07 6.807766149611611 -0.12777240317920213 GEAAAERPGEAAVASS(ph)PSKANGQENGHVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GEAAAERPGEAAVASSPSKANGQENGHVK 29 2 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 GEAAAERPGEAAVAS(0.144)S(0.428)PS(0.428)KANGQENGHVK 48.84 0.005565 51284000.0 18373.0 12360.0 16268.0 21894.0 25312.0 16821.0 20153.0 25358.0 19079.0 16138.0 True False 21483.186016708885 13587.019115605706 16655.89081673356 20667.350161305716 20352.29530371235 15938.87714832187 18243.961944915136 24692.379369021903 19357.994281078154 19063.6916516623 1.1269163606533477 0.7127171045289624 0.8736970320898584 1.0841210893957982 1.0675946545714134 0.836085551506077 0.9570004738995196 1.2952569638771303 1.015437861396074 1.0 14.218539901306967 -7.5655275892921825 24.97545058007603 1.118434596052748 0.9431087040492414 0.19751303817708676 0.13943455615389624 202.874604854633 118802.55447782075 0.06546579458333106 0.03779672306583259 2.719395726394353e-08 7.5655275892921825 -0.17532589200350657 GEAAAERPGEAAVASS(ph)PSKANGQENGHVK ddPTM_PC-9_Lapatinib_30min_R1 1 GEAAAERPGEAAVASSPSKANGQENGHVK 29 2 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 GEAAAERPGEAAVAS(0.306)S(0.6)PS(0.094)KANGQENGHVK 63.728 0.00010717 22692000.0 35835.0 31146.0 26459.0 23213.0 30001.0 28862.0 23072.0 20552.0 27367.0 18854.0 True False 35323.986328665844 31073.88335060455 24283.6431546936 24920.161456297985 28236.400164235398 27627.639540608106 24266.55526783698 21506.920948764706 24284.640272714078 22112.888778624147 1.5974387915708446 1.4052385313239906 1.0981669286994225 1.1269518743470344 1.2769204624015775 1.2493907882047008 1.097394171823209 0.9725966229050448 1.0982120208640174 1.0 14.43259988748779 -1.5228787452806058 0.5695249775020008 1.091121172479678 27.696295885184696 0.7463125095637559 0.09234421829613301 82.19630454387902 0.7066581337318114 0.04911246943516173 2694.5327497071507 0.02999999999998147 1.5228787452806058 26.60517471270502 GEAAAERPGEAAVASSPS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 GEAAAERPGEAAVASSPSK 19 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 GEAAAERPGEAAVAS(0.137)S(0.321)PS(0.542)K 84.40299999999999 0.00063997 8303700.0 20170.0 32561.0 32856.0 19800.0 27845.0 22334.0 32003.0 31338.0 34703.0 23968.0 True False 26583.640437937418 43085.70648494067 32420.30797227098 15235.415906950553 23979.202389686376 20937.451449374777 34851.20500197406 26495.432175599813 36537.32973242133 23128.88761529141 1.1493696056684515 1.8628525159357439 1.4017236155722703 0.6587180568458392 1.03676418808109 0.9052511213523392 1.5068258180705834 1.1455558354688296 1.57972706427373 1.0 14.497408260720515 -5.535463858779115 24.991057202181228 1.1212832316748742 1.5376554193143817 0.228398655381175 0.2997351367907128 287.20815735521086 570325.450061557 0.0816915349213203 0.14160752386473582 2.914312648638965e-06 5.535463858779115 0.41637218763950745 GEAAAERPGEAAVASSPS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 GEAAAERPGEAAVASSPSK 19 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 GEAAAERPGEAAVAS(0.407)S(0.083)PS(0.511)K 79.34100000000001 0.0013298 10758000.0 10184.0 21445.0 16817.0 16206.0 16876.0 18982.0 18573.0 20938.0 15778.0 17458.0 True False 10038.774292483124 21395.34542007686 15434.371175497272 17397.84330163119 15883.386859492568 18170.184109203205 19534.619061613044 21910.855917926983 14000.915490294254 20475.592038677234 0.49028005019441917 1.0449195012120902 0.7537936459342723 0.8496869476969285 0.7757229597801006 0.8874070197765591 0.9540441626651506 1.0700963311116287 0.6837856245547048 1.0 14.321617546625268 -6.920482921381181 4.099924123904441 0.9318212649193378 0.7998410526402271 0.15671319973506137 0.15717520381569025 0.4500173259414865 14.564398456161994 0.054704202627393575 0.04747084775863827 1.2009282985591317e-07 6.920482921381181 -0.13198021227911072 GEAAAERPGEAAVASSPS(ph)KANGQENGHVK ddPTM_PC-9_Lapatinib_30min_R1 1 GEAAAERPGEAAVASSPSKANGQENGHVK 29 2 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 GEAAAERPGEAAVAS(0.199)S(0.199)PS(0.603)KANGQENGHVK 52.393 0.021406 2545400.0 6190.1 5410.9 7786.6 3699.5 5684.4 5209.0 3793.9 3317.1 5639.9 5095.3 True False 6101.82803887469 5398.3713934947045 7146.4158051452205 3971.573571170223 5350.054767960394 4986.2232127720745 3990.32957830473 3471.224575668907 5004.675071220088 5976.015815939521 1.0210528597664679 0.903339542558757 1.1958495467973749 0.6645855187626927 0.8952544525887075 0.8343724927020066 0.6677240658670159 0.5808593354807207 0.8374601449131668 1.0 12.54496825098658 -5.770576171694245 24.999999961470106 0.7674574282060953 1.0264065555717836 0.4329355084348103 0.1337982018452225 172.94572156873213 473212.9400382402 0.037428451410855657 0.056404390449699957 1.695992113049748e-06 5.770576171694245 0.2589491273656883 GEAAAERPGEAAVASSPSK ddPTM_PC-9_Lapatinib_30min_R1 1 GEAAAERPGEAAVASSPSK 19 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 0 91.926 0.0011778 5012700.0 71981.0 65785.0 74134.0 66118.0 70059.0 75615.0 57264.0 67116.0 66243.0 53942.0 False True 70954.53774030143 65632.67887431839 68038.9886855157 70980.53828318212 65938.26736129352 72381.12271717419 60228.84972509607 70234.45437900422 58782.015770285354 63265.80282680303 1.1215306622212182 1.0374116179951898 1.0754465389742982 1.1219416353175666 1.0422418497052293 1.144079731594102 0.951996924625758 1.1101487887742234 0.9291277932757365 1.0 15.949138267455147 -7.723467077374428 1.0625562264447146 0.9842517628017519 1.0848307253463374 0.3179339083775713 0.058530383264694064 0.6492514140460026 1.3280793893025267 0.04676331004849877 0.01910762461918414 1.890309524727254e-08 7.723467077374428 0.10057896254458554 GEAEQS(ph)EEEADEEDKAEDAREEEYEPEK ddPTM_PC-9_Lapatinib_30min_R1 1 GEAEQSEEEADEEDKAEDAREEEYEPEK 28 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 GEAEQS(0.991)EEEADEEDKAEDAREEEY(0.009)EPEK 46.416000000000004 0.009071899999999999 39904000.0 53582.0 73929.0 44210.0 60097.0 55469.0 37377.0 68800.0 75740.0 45551.0 77775.0 True False 52817.910854264665 73757.82194268439 40575.22445553517 64516.73385771505 52206.42247624989 35778.472840042574 72362.12735901462 79259.156902464 40420.56670670513 91218.30512132675 0.5790275404044521 0.808585753096172 0.4448144964058176 0.7072783666820301 0.5723239694797189 0.39222909033943015 0.7932851554604957 0.8688953033828437 0.44311902806068304 1.0 16.4770357440471 -14.522878745274594 0.32919320045828643 4.7178361676830525 0.6159470337423102 0.3271235168619747 0.16002878399032525 430.3585944021059 3.729876245350426 1119.192150256373 0.1351281348076155 3.000000000039672e-15 14.522878745274594 -4.101889133940742 GEAGVPAEFSIWTR ddPTM_PC-9_AZD4547_30min_R2 1 GEAGVPAEFSIWTR 14 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7 O75369-2 FLNB Filamin-B 0 128.88 0.00011200000000000001 2829800.0 12734.0 12329.0 21102.0 27415.0 20373.0 22014.0 18709.0 21929.0 15303.0 18186.0 False True 16783.14711634582 16314.10814326444 20822.17369219813 21094.895307527764 17544.560613578047 20637.461099961336 20374.06475586454 18540.376928289246 16111.885338306305 17549.313675387602 0.9563420784873023 0.9296151658708168 1.1864950434728747 1.2020353443857315 0.9997291596755592 1.175969697829538 1.1609607721832773 1.0564730491022896 0.9180920482892019 1.0 14.099126989767251 -8.10536377879982 5.253223823011486 0.9619456822502104 1.0907233993867071 0.2207598625909053 0.09463295112276475 0.36269310955716044 14.507445926158832 0.07141525039715806 0.02602601504382702 7.845781717906723e-09 8.10536377879982 0.12877771713649677 GEAGVPAEFSIWTR ddPTM_PC-9_Lapatinib_30min_R1 2 GEAGVPAEFSIWTR 14 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7 O75369-2 FLNB Filamin-B 0 ; 171.49 0.0010205 13565500.0 37928.0 33842.0 42148.0 32890.0 35488.0 38286.0 35113.0 30474.0 37666.0 31957.0 False True 37387.13976485665 33763.64092824629 38682.75413598499 35308.84031782365 33400.665612092445 36648.59702902508 36930.97933077151 31889.93329080652 33423.65843943613 37480.72486997412 0.9975031137886973 0.9008267861781513 1.032070598158944 0.9420532938014128 0.8911424666402272 0.9777985125998547 0.9853325798497827 0.8508355535128299 0.8917559240219467 1.0 15.19386123425958 -6.459776930750832 0.7815333074297759 0.9229183863038478 0.9688689615453336 0.05963239895706862 0.05535975102440239 1.912256587259474 2.5875420062386825 0.03447536564664837 0.04681166276979163 3.469149927026437e-07 6.459776930750832 0.045950575241485825 GEAHLAVNDFELAR ddPTM_PC-9_AZD4547_30min_R2 1 GEAHLAVNDFELAR 14 0 Q02790 Q02790 FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed 0 129.17 1.9648e-05 2162700.0 9159.6 8772.2 8885.3 8553.7 6940.8 11908.0 12427.0 9688.9 9846.9 9443.9 False True 12072.162268484453 11607.642100279369 8767.47511644811 6581.776618347627 5977.189726928902 11163.390877547905 13532.978925711075 8191.703133772713 10367.38703115522 9113.271935499446 1.324679253941614 1.2737074217069568 0.9620556896031671 0.7222188325917565 0.6558774685133245 1.2249597023504275 1.4849747732200653 0.898876187581225 1.1376141417190184 1.0 13.153753402096093 GEAHLAVNDFELAR ddPTM_PC-9_Lapatinib_30min_R1 2 GEAHLAVNDFELAR 14 0 Q02790 Q02790 FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed 0 ; 102.5 0.0012125999999999999 4732100.0 17594.2 28744.6 22703.5 22159.1 26997.7 26003.4 27935.3 24122.7 28671.5 24486.4 False True 17343.303481618874 28678.043644762955 20836.905868044392 23788.754134590643 25409.748365520416 24891.29519888605 29381.653145527314 25243.528706245936 25442.213745720113 28718.841613922912 0.6038998269766852 0.9985794006001907 0.7255482706496994 0.8283326484539627 0.8847762283420845 0.8667235097260586 1.0230793268236513 0.8789884023040768 0.8859066841117196 1.0 14.809709938196743 -6.474091106280329 1.3165887044197884 0.9351140317279582 0.7931665659228827 0.3119072721576005 0.10187793023248924 0.598218873191006 2.138831366758383 0.0413251066092349 0.048328295133454824 3.356671906056655e-07 6.474091106280329 -0.14194746580507545 GEAS(ph)SLNGESH ddPTM_PC-9_AZD4547_30min_R2 1 GEASSLNGESH 11 0 Q8IY57-3;Q8IY57;Q8IY57-5 Q8IY57-3 YAF2 YY1-associated factor 2 1 GEAS(0.613)S(0.387)LNGESH 112.83 0.0028951 0.0 13056.0 18305.0 19986.0 30529.0 23761.0 24586.0 19788.0 25741.0 17093.0 23431.0 True False 17207.536418329735 24221.73327621505 19720.972581379574 23491.010718348156 20462.19529471497 23048.633533371914 21549.09366556458 21763.31991933483 17996.50108394888 22610.68782184135 0.7610355135551291 1.0712515013726152 0.8721969334488628 1.038933928213207 0.9049788956419542 1.0193689690017973 0.9530490109526301 0.962523568093847 0.7959289529690784 1.0 14.4647172593906 -4.737961726928717 24.937946861530065 0.9564295719185778 0.7610346586277933 0.3614414627970667 0.07835951150781686 2158.240003448617 2292359.7322212155 0.01809497299580496 1.0666179883665923 1.8282613282357653e-05 4.737961726928717 -0.1953949132907845 GEAS(ph)SLNGESH ddPTM_PC-9_Lapatinib_30min_R1 1 GEASSLNGESH 11 0 Q8IY57-3;Q8IY57;Q8IY57-5 Q8IY57-3 YAF2 YY1-associated factor 2 1 GEAS(0.627)S(0.373)LNGESH 164.64 6.7589e-13 0.0 24460.0 20412.0 26632.0 21755.0 25662.0 19719.0 17878.0 23313.0 21260.0 17621.0 True False 24111.195914585358 20364.73726810955 24442.41976249292 23354.93527255256 24152.611613433182 18875.664337234113 18803.63536227416 24396.207088290754 18865.47492227506 20666.766371493377 1.1666651415696576 0.985385759051284 1.1826920246317525 1.1300720612377513 1.168669117329743 0.9133341906487212 0.9098489344811523 1.1804559382807736 0.912841156819631 1.0 14.335025054488067 -6.753378183619275 24.999940604388893 0.9899840921455789 1.12214456977268 0.38614253644615215 0.09011447585825377 213.85256236222241 663213.5594226656 0.030028412154040444 0.029523982692870175 1.76450062440758e-07 6.753378183619275 0.13216047762710104 GEATVSFDDPPSAK ddPTM_PC-9_Lapatinib_30min_R1 2 GEATVSFDDPPSAK 14 0 H3BPE7;P35637-2;P35637;Q92804-2;Q92804;A0A075B7D9 H3BPE7;Q92804-2 FUS;TAF15 RNA-binding protein FUS;TATA-binding protein-associated factor 2N 0 ; 164.81 1.2137999999999998e-13 0.0 122351.0 115150.0 125160.0 132075.0 112620.0 93255.0 115236.0 95902.0 108907.0 105007.0 False True 120606.2523035743 114883.37724979478 114869.82793157166 141788.23608928442 105995.91301943896 89266.70103802254 121202.35622592157 100357.95702746375 96640.74681844833 123157.32003696756 0.9792861055061323 0.932818099771177 0.9327080834260743 1.1512773747165372 0.8606545919286215 0.7248184761671314 0.9841262881454453 0.8148761031608983 0.7846934862616377 1.0 16.91014285352975 -6.478332070589009 24.981477537114777 0.8505565113554232 0.9916079991939597 0.3210647901999357 0.09703963909791548 520.9707260996652 292156.8691615117 0.02954364542717048 0.033497611957375356 3.3240529210328806e-07 6.478332070589009 0.1410514878385365 GEAVLRPGLDAEPELS(ph)PEEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GEAVLRPGLDAEPELSPEEQR 21 1 C9JQV0;Q9BRJ6 C9JQV0 C7orf50 Uncharacterized protein C7orf50 1 GEAVLRPGLDAEPELS(1)PEEQR 106.31 3.5647e-05 13391000.0 19398.0 24982.0 31221.0 28446.0 32157.0 15417.0 28066.0 22225.0 22193.0 19093.0 True False 22681.698272036083 27462.047859713737 31965.427046301837 26852.262843176308 25856.06669095601 14608.505379922617 25407.385299756283 21641.617299334004 22517.53063996894 22554.409759895163 1.0056436197398193 1.217591067647668 1.4172584158305377 1.1905548905528585 1.1463863149693967 0.6477006286326563 1.126493025986169 0.9595293128803473 0.998364882064358 1.0 14.461121911334303 -6.540874474577023 24.99661175608027 0.9486873302320198 1.2165584796585842 0.4256656886479665 0.14590032666324307 230.6848983819972 320426.08162436506 0.04820268904805896 0.04821097736206129 2.8782301979394424e-07 6.540874474577023 0.2678711494265644 GECQCGHCVCYGEGR ddPTM_PC-9_Lapatinib_30min_R1 1 GECQCGHCVCYGEGR 15 0 P16144-4;P16144-2;P16144-3;P16144;P16144-5 P16144-4 ITGB4 Integrin beta-4 0 88.992 0.008374600000000001 0.0 8407.3 10211.0 7281.1 5187.8 4915.6 7348.8 2742.8 3642.7 7743.3 3898.9 False True 8287.410360290005 10187.357056861965 6682.476063858788 5569.328117993481 4626.474072441435 7034.508954889508 2884.808763376531 3811.953140330149 6871.168013436143 4572.819670042309 1.81231952236886 2.227806428406067 1.461346946969584 1.2179199093459885 1.0117333300393694 1.5383307155045594 0.6308599445273643 0.83361107924356 1.5026107542466396 1.0 12.158868311992975 -5.523156026299974 2.5269630525846387 1.087348627888981 2.0225705091507296 0.6256196668296379 0.27950225022069886 0.1771911497268561 2.2460341679694027 0.0793161041669299 0.18199834902018905 2.9980852218955122e-06 5.523156026299974 0.9352218812617485 GECSGPATVNNSSDTESIPS(ph)PHTEAAK ddPTM_PC-9_Lapatinib_30min_R1 1 GECSGPATVNNSSDTESIPSPHTEAAK 27 0 Q9Y618;A0A384DVL6;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 GECSGPATVNNS(0.006)S(0.019)DT(0.048)ES(0.182)IPS(0.708)PHT(0.036)EAAK 83.992 5.708e-07 4744300.0 9762.9 11235.0 12067.0 8902.9 11599.0 12106.0 12132.0 9870.9 12769.0 8172.3 True False 9623.67925570341 11208.986047776345 11074.897839967032 9557.648965203776 10916.769624511393 11588.254600464341 12760.135597668095 10329.538049492092 11330.820756468967 9584.87116609474 1.0040488900618663 1.1694456663566544 1.1554560982669306 0.9971598782686555 1.1389584101169847 1.2090151656348096 1.3312787805438062 1.0776919032601624 1.1821568135991543 1.0 13.226543324872114 -6.517542637991257 24.06519720146958 1.1754095855967 1.08995947855703 0.11832458546030955 0.09611846361206466 289.38179981300186 1305087.4860586638 0.030952997020865597 0.0318961643209162 3.037087903297983e-07 6.517542637991257 -0.08545010703967004 GEDLTEEEDGGIIRR ddPTM_PC-9_Lapatinib_30min_R1 1 GEDLTEEEDGGIIRR 15 1 Q02790 Q02790 FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed 0 70.563 0.014844999999999999 3456700.0 10741.0 14043.0 21222.0 11853.0 17468.0 18107.0 11651.0 14579.0 21115.0 14188.0 False True 10587.831370341843 14010.48429629934 19477.209079288998 12724.709160448878 16440.566583409356 17332.605819478595 12254.231771219167 15256.393563256157 18736.806349192746 16640.37689567834 0.6362735313460118 0.8419571494163689 1.170478841999511 0.7646887591682856 0.9879924407048211 1.041599353676901 0.7364155179923663 0.9168298085374728 1.1259844934196694 1.0 14.022400489673181 -4.878998181975936 3.917258992920414 0.9556602283624883 0.6346999543348077 0.37092921237354526 0.13161236068817928 0.24613279600211077 6.324039062194906 0.032532534269239605 0.18236260716077446 1.3213011653466217e-05 4.878998181975936 -0.32096027402768057 GEDS(ph)AEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVK 41 1 Q12906-7;Q12906-4;Q12906-6 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 GEDS(0.75)AEET(0.248)EAKPAVVAPAPVVEAVS(0.001)T(0.001)PS(0.001)AAFPSDATAENVK 50.18899999999999 0.00067506 3406000.0 22195.0 37907.0 23753.0 21663.0 25177.0 19364.0 23520.0 13145.0 16693.0 17737.0 True False 25952.175128767958 41670.15644136454 24319.36160375412 20449.29234239359 20243.747584606732 18348.517751626227 21292.01532994611 12799.95767827876 16937.103544946665 20952.577693985255 1.238614909716713 1.9887842464999697 1.1606859050442921 0.9759797883132947 0.9661697897160404 0.8757164879476113 1.016200280505739 0.610901334681755 0.8083541697024089 1.0 14.354840122164553 -5.508721426664298 3.8422686612756407 0.8892743367413407 1.6175015349949025 0.6598087053349284 0.2041296568767893 0.11711944103670531 3.810959404418642 0.05386723214742401 0.1105800223429185 3.0994067415093947e-06 5.508721426664298 0.7282271982535617 GEDSAEET(ph)EAKPAVVAPAPVVEAVSTPSAAFPSDATAENVK ddPTM_PC-9_AZD4547_30min_R2 1 GEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVK 41 1 Q12906-7;Q12906-4;Q12906-6 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 GEDS(0.473)AEET(0.522)EAKPAVVAPAPVVEAVS(0.002)T(0.002)PSAAFPSDATAENVK 70.178 2.416e-07 4457100.0 20553.0 27062.0 30148.0 22608.0 24514.0 33382.0 32757.0 37257.0 30514.0 26657.0 True False 27088.426471042516 35809.262273746644 29748.217821646755 17396.0748901181 21110.654242441084 31294.618262874028 35672.30954128253 31499.78673068869 32126.907744434327 25723.74654375931 1.0530513673411341 1.392070249674969 1.156449655225817 0.6762652112329439 0.8206679461146619 1.2165653323336074 1.3867462688842571 1.2245411716020298 1.2489202414501497 1.0 14.65081315932525 -6.965763948544709 24.70874560515116 1.2434626511034368 1.027876413836865 0.18854091543487284 0.19913810759385492 283.8606167218363 204866.10530923668 0.07779228370224388 0.06860601987662576 1.0820219013078647e-07 6.965763948544709 -0.21558623726657178 GEDSAEET(ph)EAKPAVVAPAPVVEAVSTPSAAFPSDATAENVK ddPTM_PC-9_Lapatinib_30min_R1 1 GEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVK 41 1 Q12906-7;Q12906-4;Q12906-6 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 GEDS(0.466)AEET(0.534)EAKPAVVAPAPVVEAVSTPSAAFPSDATAENVK 77.627 3.7511e-10 4347700.0 77999.0 123100.0 102080.0 96660.0 124640.0 123110.0 114760.0 125150.0 119200.0 102650.0 True False 76886.71995673537 122814.96951324167 93687.37644019499 103768.69884830755 117308.92025166836 117844.87228342675 120701.71127500752 130964.92588253733 105774.44076835304 120392.91572747275 0.6386315963206662 1.0201179095226134 0.7781801435249752 0.8619169842451812 0.9743839123990861 0.9788356031694267 1.0025648979897934 1.0878125601592363 0.8785769505557055 1.0 16.87739097662132 -6.246937335247721 2.9999965831697097 0.9945845973883928 0.8308010183805506 0.3947221188671376 0.09906771749735255 0.28071534330213777 5.132316618044006 0.0300236773396236 0.03790274145653471 5.663209981235286e-07 6.246937335247721 -0.16378357900784213 GEDVPS(ph)EEEEEEENGFEDR ddPTM_PC-9_Lapatinib_30min_R1 2 GEDVPSEEEEEEENGFEDR 19 0 Q9ULX3 Q9ULX3 NOB1 RNA-binding protein NOB1 1 GEDVPS(1)EEEEEEENGFEDR;GEDVPS(1)EEEEEEENGFEDR 288.82 1.824299999999999e-227 6516800.0 34294.0 48859.0 43266.0 40447.0 46600.0 45699.0 46732.0 56283.0 46492.0 46263.0 True False 33804.96127125062 48745.86998738798 39708.83649158976 43421.60730723665 43859.07961912501 43744.56029957212 49151.554298567855 58898.11365119323 41255.581377535855 54259.49790842733 0.6230238497286241 0.8983840961752985 0.7318319929647261 0.8002581848530634 0.8083207790301544 0.8062101933453004 0.9058608389911744 1.0854894704443154 0.7603384286224335 1.0 15.727588077217636 -7.284016896533162 3.2402133528199606 0.9501838093178177 0.7814283742203114 0.3857675740292127 0.09988242890834044 0.2614820030751165 5.68139646039228 0.041528228508846264 0.0280687620439136 5.199757661160172e-08 7.284016896533162 -0.16875543509750623 GEEDTGQEEGGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GEEDTGQEEGGSR 13 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 0 118.77 0.0015257 0.0 545.33 1184.2 1294.1 2800.6 3165.7 801.12 2537.6 681.23 752.35 851.19 False True 637.6435982415421 1301.7595498948444 1324.9562519015794 2643.6914616677045 2545.403810167596 759.1078569088407 2297.220157366974 663.3484343228482 763.3516954436366 1005.504008983668 0.6341532132587441 1.2946338734249527 1.3177035994523818 2.6292202100117583 2.5314705733897678 0.7549525910653735 2.2846454482950618 0.6597173441340528 0.7591731993343404 1.0 9.973703118398168 -7.78511673226334 24.99910540848721 0.7820833181536504 1.6487816101366006 0.25214080341118184 0.6535399020074126 348.72579179749147 368187.4711719271 0.37302981287476356 0.1793557999778032 1.64014886494453e-08 7.78511673226334 0.8666982919829502 GEEDTGQEEGGSR ddPTM_PC-9_Lapatinib_30min_R1 1 GEEDTGQEEGGSR 13 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 0 127.52 0.00053501 746960.0 1018.3 2277.3 612.15 920.31 882.12 2145.4 2146.6 1992.3 1138.9 565.09 False True 1003.7788552666508 2272.027051766896 561.8213899673343 987.9926674641615 830.235435914647 2053.6462431716673 2257.7404446055343 2084.869531248732 1010.62508885132 662.7650535649052 1.514531959504334 3.428103276637826 0.8476931409484985 1.4907132808978234 1.2526843886064087 3.0986036939114983 3.406547210752161 3.145714337282207 1.5248617642335431 1.0 9.37235372356857 -6.7622745777898245 24.999983243604476 2.6299651497115843 1.74264933258721 0.11196474772230314 0.9467849426417767 42.0596791744918 1258945.281854627 0.32547005848987276 0.30391747547528714 1.728723047977697e-07 6.7622745777898245 -0.8873158171243742 GEEDWLYER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GEEDWLYER 9 0 J3QQZ9;Q9NVS9-4;Q9NVS9-3;Q9NVS9 J3QQZ9 PNPO Pyridoxine-5-phosphate oxidase 0 99.139 0.019522 1086800.0 10424.0 15143.0 14855.0 17111.0 15522.0 12217.0 12126.0 11365.0 10388.0 10265.0 False True 12188.577316615329 16646.296963399458 15209.19953790122 16152.32614461049 12480.575525609316 11576.319013200655 10977.33749536252 11066.680792212868 10539.904847834789 12125.963242304708 1.0051636371527315 1.3727814137951813 1.254267329859603 1.3320447886777955 1.0292440506554932 0.9546721181549958 0.9052755047999078 0.9126434387994641 0.8692014512351048 1.0 13.565811733834762 -6.459212766117734 3.3859726216998847 0.9239011858628616 1.250638996336874 0.6981825074695807 0.09675321506131745 0.13068788457190203 2.9470992626553167 0.031164450542190966 0.034514828756140654 3.4736594097559657e-07 6.459212766117734 0.3267378104740124 GEEDWLYER ddPTM_PC-9_Lapatinib_30min_R1 3 GEEDWLYER 9 0 J3QQZ9;Q9NVS9-4;Q9NVS9-3;Q9NVS9 J3QQZ9 PNPO Pyridoxine-5-phosphate oxidase 0 ;; 120.12 0.0078156 4945500.0 29740.5 33636.0 31796.0 30777.5 31092.1 33360.9 28275.4 28166.5 34090.3 27181.0 False True 29316.39501626025 33558.117908589695 29181.85561610936 33040.980020730225 29263.323807420522 31934.132075056248 29739.361859405235 29475.218416863598 30250.69142722641 31879.199633594086 0.9196088783034198 1.0526650070984334 0.9153885904135973 1.0364432106354347 0.9179441185400097 1.0017231436828256 0.9328766782484117 0.9245909168247377 0.9489162769114328 1.0 14.960327788704074 -6.820219189428478 1.3343999055629758 0.9489062934238707 0.9782688695008269 0.01728995752204643 0.04958793059121256 1.3458649552710813 5.004732719134195 0.022682722882901508 0.019422196693863886 1.512797543315036e-07 6.820219189428478 0.02936257607695625 GEEGS(ph)DDDETENGPKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GEEGSDDDETENGPKPK 17 1 Q6PD62 Q6PD62 CTR9 RNA polymerase-associated protein CTR9 homolog 1 GEEGS(0.99)DDDET(0.01)ENGPKPK 61.861999999999995 0.014511000000000001 10254000.0 14981.0 16135.0 19210.0 18069.0 18681.0 18713.0 20863.0 15813.0 15471.0 15058.0 True False 17516.987411762682 17736.776167499847 19668.039254330684 17056.652510488388 15020.592152680567 17731.657337646237 18886.70560496026 15397.925505258425 15697.23410674355 17787.896200937583 0.9847700489077161 0.9971261338125506 1.1056978876059553 0.9588909400983208 0.8444276930224524 0.9968383634210558 1.0617728702489708 0.8656406205275031 0.8824671523502686 1.0 14.118608270708068 -5.9775309215578245 24.84561098401654 0.9400459290376386 1.0270414840272886 0.2404576648373734 0.06964213106487815 330.27547353423074 365205.5396127582 0.020569922860353043 0.030507782734431874 1.053098704340119e-06 5.9775309215578245 0.08699555498964995 GEEGS(ph)DDDETENGPKPK ddPTM_PC-9_Lapatinib_30min_R1 2 GEEGSDDDETENGPKPK 17 1 Q6PD62 Q6PD62 CTR9 RNA polymerase-associated protein CTR9 homolog 1 GEEGS(0.998)DDDET(0.002)ENGPKPK;GEEGS(0.999)DDDET(0.001)ENGPKPK 68.567 0.0081402 28783000.0 37594.0 43644.0 43808.0 47943.0 51915.0 45098.0 50455.0 50702.0 52828.0 41874.0 True False 37057.902666104725 43542.94499947938 40206.27534377029 51468.88815315958 48861.46176881703 43169.263668572676 53067.31302178895 53057.8000167511 46877.95433649799 49111.86510640223 0.7545610940618472 0.886607440078734 0.8186672458205827 1.0479929451192864 0.9949013677846954 0.878998661016951 1.0805395581458195 1.080345857397187 0.954513827461767 1.0 15.583783991914949 -4.844293793526693 0.6226320752159913 1.0189253535468172 0.6159501030628953 0.5753478053010368 0.06917152567592831 2.4413872579451117 0.7562197965067659 0.03492027302539536 0.6990548239355906 1.431219373855765e-05 4.844293793526693 -0.4029752504839219 GEELSCEER ddPTM_PC-9_AZD4547_30min_R2 2 GEELSCEER 9 0 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 ; 125.31 0.0065911 53962000.0 32010.0 34377.0 47269.0 45303.0 50774.0 49432.0 47003.0 70650.0 45274.0 45805.0 False True 42188.51415063839 45488.69297112512 46642.182174984046 34859.0932743728 43724.906523035956 46341.00922564223 51186.17594312367 59732.66587549068 47667.09121129711 44201.38089195694 0.9544614511877202 1.0291237977907253 1.0552200233063587 0.7886426299571988 0.9892203736782421 1.0484063685457081 1.1580221004461357 1.35137556044906 1.078407286139126 1.0 15.43180382099554 -7.064692828316143 2.610128811380315 1.1763406534714036 0.9632774403442977 0.38331506955461747 0.10743771135274213 0.26990908202044683 3.627154345636093 0.04537644213248497 0.03478582019494614 8.616029389532723e-08 7.064692828316143 -0.21306321312710585 GEELSCEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GEELSCEER 9 0 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 ; 125.31 0.0065911 48814000.0 46660.0 62791.0 60930.0 55577.0 64048.0 44494.0 56936.0 41518.0 46167.0 38317.0 False True 54558.616422992265 69024.47550873774 62382.80227831181 52463.20087306509 51498.254172415036 42160.656312789564 51542.60989905659 40428.1964919572 46842.1050356169 45263.5687827949 1.2053538395260273 1.5249454995465268 1.378212190418889 1.1590601952934572 1.1377417989186482 0.9314479049388439 1.13872174212318 0.8931729772780164 1.0348743215630407 1.0 15.46606271718702 -6.0672967569687 1.6155304481830832 1.0057460205315112 1.3897641800829907 0.7031714442549899 0.10114251750844283 0.19298189538293142 1.0097164092108821 0.033525939697752485 0.053458255680941175 8.564524243009237e-07 6.0672967569687 0.38401815955147955 GEELSCEER ddPTM_PC-9_Lapatinib_30min_R1 2 GEELSCEER 9 0 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 ; 143.73 0.0027088 57471000.0 29105.0 37331.0 41521.0 42938.0 48176.0 33971.0 40184.0 37015.0 44927.0 35159.0 False True 28689.957362796675 37244.56236310981 38107.30365569498 46095.80375696903 45342.38239766021 32518.13952026878 42264.530898177916 38734.852029901005 39866.848157716435 41236.18630357731 0.695747107930487 0.9032009431938856 0.9241228899091743 1.1178483727281574 1.0995774939964968 0.7885826123898314 1.024937917076764 0.9393412801256232 0.9667928033940887 1.0 15.331623291903076 -4.7002695548260505 1.7754743080093445 0.984519529061405 0.5584402140012944 0.4975181730480148 0.08752589495498087 0.9954736224101051 2.7206925976441068 0.024835545500747725 0.7687892809298359 1.9940242939161025e-05 4.7002695548260505 -0.42607931506011065 GEFS(ph)ASPMLK ddPTM_PC-9_Lapatinib_30min_R1 1 GEFSASPMLK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 GEFS(0.637)AS(0.363)PMLK 107.03 0.0022314 38076000.0 31402.0 29703.0 29989.0 29475.0 30737.0 36996.0 31944.0 32230.0 31063.0 25004.0 True False 30954.20172157849 29634.224528446895 27523.42018088765 31642.689825717607 28929.110091267066 35413.76732188819 33597.904016807566 33727.523461399665 27564.35783210866 29325.908084264254 1.0555240653634848 1.010513449175955 0.938535990149141 1.0790011935792876 0.9864693706378319 1.2075932046206805 1.1456730997133415 1.1500930632561464 0.9399319452583018 1.0 14.83988816191682 -6.710958433048876 24.999986413513685 1.1016037070542106 1.0132323064077433 0.1689162352099739 0.08025309683347766 165.486851065237 81954.30593863725 0.02633397759693463 0.02633393880012944 1.9455462837520183e-07 6.710958433048876 -0.08837140064646731 GEFSAS(ph)PMLK ddPTM_PC-9_AZD4547_30min_R2 8 GEFSASPMLK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 GEFS(0.044)AS(0.956)PMLK;GEFS(0.168)AS(0.832)PMLK;GEFS(0.069)AS(0.931)PMLK;GEFS(0.027)AS(0.973)PMLK;GEFS(0.086)AS(0.914)PMLK;GEFS(0.105)AS(0.895)PMLK;GEFS(0.315)AS(0.685)PMLK;GEFS(0.026)AS(0.974)PMLK 113.22 0.0013379000000000002 2031722000.0 6147949.0 6210840.0 8224903.0 10139121.0 9378569.0 8490848.0 7787271.0 8767787.0 7243225.0 7705902.0 True False 8102868.896716766 8218372.570404125 8115835.412163847 7801703.301307899 8076516.580234831 7959913.932301474 8480323.033057118 7412926.9828516655 7626087.086163091 7436120.716474032 1.0896634422254088 1.1051962284847108 1.0914071626330608 1.0491630782733197 1.0861196164207048 1.070439041510855 1.1404229915565725 0.996880936377084 1.025546434348249 1.0 22.82611876019007 -7.780775048989477 24.99992998500983 1.008410218715971 1.088444612037693 0.7285570324139663 0.02315726884194404 133.57177680734114 172698.40519058536 0.012611274755063552 0.0060720932956883165 1.656627822875626e-08 7.780775048989477 0.08003439332172202 GEFSAS(ph)PMLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 GEFSASPMLK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 GEFS(0.13)AS(0.87)PMLK;GEFS(0.042)AS(0.958)PMLK;GEFS(0.046)AS(0.954)PMLK;GEFS(0.157)AS(0.843)PMLK;GEFS(0.298)AS(0.702)PMLK;GEFS(0.051)AS(0.949)PMLK 90.913 0.0074029 1876539000.0 1310060.0 1273150.0 1370770.0 1459310.0 1621330.0 1411490.0 1516340.0 1340530.0 1269200.0 1029490.0 True False 1531827.2831355613 1399539.9180447722 1403454.355474175 1377549.5918468519 1303642.0253147879 1337468.979613864 1372701.2978490838 1305342.5079089396 1287759.6489095006 1216128.3875616444 1.2595933939235624 1.1508159272976686 1.1540346971820319 1.1327336866207518 1.0719608543375996 1.0997761365438639 1.128747023660364 1.0733591298910232 1.0589010684073232 1.0 20.213864112514415 -1.5228787452803376 0.1923058388869594 1.0180317132915915 1.9670551554717097 0.8229050622449308 0.02803066959429635 23.916552747925813 0.2817664840015639 0.05795781722566994 6.75895974223513 0.029999999999999995 1.5228787452803376 0.9490234421801182 GEFSAS(ph)PMLK ddPTM_PC-9_Lapatinib_30min_R1 7 GEFSASPMLK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 GEFS(0.015)AS(0.985)PMLK;GEFS(0.076)AS(0.924)PMLK;GEFS(0.022)AS(0.978)PMLK;GEFS(0.046)AS(0.954)PMLK;GEFS(0.035)AS(0.965)PMLK;GEFS(0.255)AS(0.745)PMLK;GEFSAS(1)PMLK 140.63 0.0001234 1324967600.0 2663143.0 2275646.0 2486855.0 2146208.0 2281416.0 2270697.0 2136609.0 2074821.0 2229393.0 1724882.0 True False 2625166.092459391 2270376.8815022684 2282395.3814379033 2304047.2958600074 2147227.596316433 2173584.582563237 2247232.1595118726 2171224.7581664515 1978295.2837909479 2023025.5554392033 1.2976435643144713 1.1222680185121856 1.1282088727457475 1.138911611702203 1.0613942026304581 1.074422701541873 1.1108273711470706 1.0732562188000012 0.9778894183872312 1.0 20.948083113873132 -1.5228787452803376 0.30733879847997186 1.027338409522739 3.0487462107860996 0.7532077583231032 0.0414846253695832 29.74008466564706 0.4244947757575907 0.04180181557821106 33.32560038795513 0.029999999999999995 1.5228787452803376 2.0214078012633605 GEFVTTVQQR ddPTM_PC-9_Lapatinib_30min_R1 1 GEFVTTVQQR 10 0 A0A5K1VW95;P40925;P40925-3;B9A041;P40925-2;B8ZZ51 A0A5K1VW95 MDH1 Malate dehydrogenase, cytoplasmic 0 117.31 0.004457399999999999 5372100.0 24849.0 24354.0 23508.0 25848.0 21724.0 21022.0 23438.0 19762.0 21802.0 25256.0 False True 24494.64870325151 24297.60980930531 21575.2629835042 27748.94814640029 20446.237031027296 20122.938064675473 24651.504956985245 20680.214664727908 19346.42917476204 29621.465948495385 0.8269222308525116 0.8202703354234061 0.7283658081277409 0.9367851069440333 0.6902506805901636 0.6793363333085685 0.8322175884153841 0.6981496020718838 0.6531219355720218 1.0 14.854355420050979 -6.301744013147429 24.99360455481452 0.7434466089624666 0.8204049904402219 0.08021736536310076 0.10625831211873132 1160.3347395985054 719540.9061765324 0.03135214772552415 0.03555038955194004 4.99178632377762e-07 6.301744013147429 0.07695838147775524 GEGDAPFSEPGT(ph)TSTQRPSSPETATK ddPTM_PC-9_Lapatinib_30min_R1 1 GEGDAPFSEPGTTSTQRPSSPETATK 26 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 GEGDAPFS(0.013)EPGT(0.183)T(0.183)S(0.183)T(0.183)QRPS(0.121)S(0.121)PET(0.01)AT(0.002)K 63.979 0.00043459 415760000.0 23738.0 43539.0 41296.0 35018.0 47451.0 42180.0 41952.0 45074.0 41497.0 30809.0 True False 23399.491766983952 43438.188120528175 37900.80228716985 37593.34053662354 44660.02547225536 40376.059726382446 44124.06928728752 47168.30259072693 36823.17087721771 36134.29459958799 0.6475701830152997 1.202131897187318 1.0488872885760443 1.0403784259026931 1.235945684484583 1.1173889008709974 1.2211133433276051 1.3053611012310935 1.0190643344574262 1.0 15.141081110359801 -4.75718252667095 24.999983476839542 1.1418715054926405 0.6475694557869471 0.6775003833647245 0.1001223583677282 72.44242388775486 425390.39788176614 0.02460018252265954 0.18649221639897315 1.7491114119965735e-05 4.75718252667095 -0.49430204970569336 GEGDAPFSEPGTTS(ph)TQRPSSPETATK ddPTM_PC-9_AZD4547_30min_R2 1 GEGDAPFSEPGTTSTQRPSSPETATK 26 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 GEGDAPFS(0.03)EPGT(0.033)T(0.135)S(0.202)T(0.202)QRPS(0.191)S(0.191)PET(0.014)AT(0.002)K 79.416 1.9742000000000002e-05 479260000.0 267610.0 306180.0 331340.0 304630.0 289210.0 434160.0 324020.0 391110.0 315780.0 323870.0 True False 352704.4133662091 405146.69732376497 326946.2151062897 234402.25998658332 249058.1836279836 407011.9065666951 352857.1522900865 330672.93631370366 332471.48612235324 312531.4098783562 1.128540691329198 1.2963391343015942 1.0461227408584117 0.7500118470582449 0.7969060892949041 1.3023072040186703 1.1290294067640303 1.0580470501905985 1.063801831155973 1.0 18.253641664526917 -5.370358675394965 6.490631897578839 1.0155068187316998 1.2107688067802433 0.20777276803480504 0.15237396483905444 0.3865650967970072 19.754618585490604 0.04432149300409681 0.09341913584128093 4.262273604854995e-06 5.370358675394965 0.19526198804854356 GEGDAPFSEPGTTST(ph)QRPSSPETATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GEGDAPFSEPGTTSTQRPSSPETATK 26 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 GEGDAPFS(0.003)EPGT(0.019)T(0.019)S(0.019)T(0.363)QRPS(0.273)S(0.273)PET(0.029)AT(0.002)K 65.207 0.00035823 30342000.0 50905.0 58572.0 48562.0 57485.0 61571.0 47434.0 61464.0 42288.0 41883.0 41649.0 True False 59522.21108042052 64386.64107113733 49719.90225241056 54264.30181888456 49506.60454112174 44946.47753721535 55641.68495917547 41177.98480783968 42495.45964014867 49199.6340066974 1.209810037861622 1.3086813016205074 1.0105746365032378 1.102941168454581 1.0062392849179032 0.9135530872261554 1.1309369689945485 0.8369571367590711 0.863735279704802 1.0 15.586359963026839 -5.260304222917205 0.5638313584926223 0.9293169882096836 1.3935860864453429 0.5813100682086165 0.09267211302531386 1.7319203442519173 0.6100175515557882 0.0552185053997163 0.49165399888434885 5.491560557384611e-06 5.260304222917205 0.4642690982356593 GEGDAPFSEPGTTSTQRPS(ph)SPETATK ddPTM_PC-9_AZD4547_30min_R2 3 GEGDAPFSEPGTTSTQRPSSPETATK 26 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 GEGDAPFSEPGTTST(0.006)QRPS(0.493)S(0.493)PET(0.006)AT(0.001)K;GEGDAPFS(0.022)EPGT(0.08)T(0.105)S(0.105)T(0.105)QRPS(0.268)S(0.268)PET(0.042)AT(0.007)K;GEGDAPFS(0.014)EPGT(0.058)T(0.044)S(0.058)T(0.248)QRPS(0.287)S(0.287)PET(0.004)ATK 95.51 2.1239e-09 696470000.0 191477.0 212343.0 248775.0 233306.0 243826.0 273633.0 251154.0 296590.0 250561.0 203638.0 True False 252362.70303098316 280978.7221563141 245476.08095330285 179520.90624176784 209974.9686431201 256522.68525328068 273506.21945023275 250758.83046018108 263805.14292958035 196508.69560258306 1.2842317346676537 1.4298538865911679 1.2491868627012357 0.9135519712818656 1.068527619092089 1.3054011908565575 1.3918275657549963 1.2760698944707916 1.3424604042107982 1.0 17.58423362827009 GEGDAPFSEPGTTSTQRPS(ph)SPETATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 GEGDAPFSEPGTTSTQRPSSPETATK 26 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 GEGDAPFS(0.001)EPGT(0.008)T(0.008)S(0.008)T(0.007)QRPS(0.477)S(0.477)PET(0.015)AT(0.001)K;GEGDAPFS(0.004)EPGT(0.07)T(0.07)S(0.07)T(0.07)QRPS(0.306)S(0.306)PET(0.095)AT(0.008)K;GEGDAPFSEPGT(0.009)T(0.033)S(0.033)T(0.122)QRPS(0.397)S(0.397)PET(0.007)AT(0.001)K;GEGDAPFS(0.003)EPGT(0.071)T(0.102)S(0.102)T(0.102)QRPS(0.307)S(0.307)PET(0.007)AT(0.001)K;GEGDAPFS(0.008)EPGT(0.049)T(0.06)S(0.06)T(0.059)QRPS(0.371)S(0.371)PET(0.021)AT(0.001)K;GEGDAPFS(0.002)EPGT(0.14)T(0.14)S(0.14)T(0.032)QRPS(0.27)S(0.27)PET(0.004)AT(0.001)K 73.831 4.6427e-05 1323453600.0 328195.0 409810.0 387249.0 386325.0 442901.0 313651.0 415915.0 307820.0 319955.0 276730.0 True False 383751.9313532778 450493.22846006195 396482.48481001036 364680.46273254824 356117.7284414313 297202.58940897114 376516.5202361616 299740.0511622491 324633.73657960846 326898.9584065253 1.1739160418983385 1.3780809539926315 1.2128594313749763 1.1155754809075855 1.08938165535104 0.9091573459202512 1.1517825632467535 0.9169195662884251 0.9930705749631057 1.0 18.318485254710744 -5.978011460617307 1.460206691655519 1.0004269519673905 1.281345987210888 0.6555420363250234 0.08081173109952 0.23475812359025863 1.0146389270186413 0.027086225740895784 0.048942865910819096 1.0519341139186267e-06 5.978011460617307 0.2809190352434976 GEGDAPFSEPGTTSTQRPS(ph)SPETATK ddPTM_PC-9_Lapatinib_30min_R1 3 GEGDAPFSEPGTTSTQRPSSPETATK 26 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 GEGDAPFSEPGTT(0.011)S(0.011)T(0.006)QRPS(0.474)S(0.474)PET(0.02)AT(0.003)K;GEGDAPFSEPGT(0.061)T(0.061)S(0.061)T(0.061)QRPS(0.355)S(0.355)PET(0.039)AT(0.004)K;GEGDAPFS(0.001)EPGT(0.034)T(0.034)S(0.034)T(0.034)QRPS(0.401)S(0.401)PET(0.048)AT(0.015)K 87.74799999999999 4.4066000000000003e-07 714310000.0 106953.0 181879.0 157431.0 157534.0 206873.0 186596.0 192566.0 177824.0 174814.0 155484.0 True False 105427.83060722191 181457.87035011282 144487.63088123413 169119.5758780183 194705.13686796665 178615.72405652085 202536.1252473256 186086.3522184278 155124.60644697037 182359.20223059301 0.5781327693784739 0.9950573819721997 0.7923243198801104 0.927398090194356 1.067701188019907 0.9794719535494647 1.1106438434141583 1.020438507858363 0.8506541186269035 1.0 17.47642347738733 -4.225065021786966 0.9148130144043923 0.9967275031688034 4.085444367041289e-30 0.5670853439272344 0.09767429210410691 4.067942256430721 1.3149398848185148 0.03298599744996103 5.151156490015063 5.955729687423401e-05 4.225065021786966 -0.9967275031688034 GEGDIHENVDTDLPGS(ph)LGQSEEKPVPAAPVPSPVAPAPVPSR ddPTM_PC-9_AZD4547_30min_R2 2 GEGDIHENVDTDLPGSLGQSEEKPVPAAPVPSPVAPAPVPSR 42 1 Q9UK76;Q9UK76-3 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 GEGDIHENVDT(0.002)DLPGS(0.982)LGQS(0.016)EEKPVPAAPVPSPVAPAPVPSR;GEGDIHENVDT(0.032)DLPGS(0.483)LGQS(0.483)EEKPVPAAPVPS(0.002)PVAPAPVPSR 94.574 4.865699999999999e-23 11986600.0 35875.0 35724.0 36948.0 33443.0 36723.0 48776.0 48013.0 54375.0 49540.0 41402.0 True False 47282.50375364425 47271.08437910444 36458.04537860567 25733.233039199367 31624.645335121313 45726.02900934468 52286.06398649444 45972.59316319613 52158.583262085514 39952.52858178801 1.1834671154004892 1.1831812918257327 0.9125341166822851 0.644095228829387 0.791555539979943 1.1445090118823786 1.308704751426636 1.1506804398896622 1.3055139465155536 1.0 15.285999193265008 -6.92146450936051 6.919170620188086 1.2069504365357335 0.938932907600344 0.32682209292089714 0.17175961613985874 0.2761392146083499 20.044204076469782 0.06765310137549257 0.059594049779580785 1.1982170377460348e-07 6.92146450936051 -0.26801752893538955 GEGDIHENVDTDLPGS(ph)LGQSEEKPVPAAPVPSPVAPAPVPSR ddPTM_PC-9_Lapatinib_30min_R1 2 GEGDIHENVDTDLPGSLGQSEEKPVPAAPVPSPVAPAPVPSR 42 1 Q9UK76;Q9UK76-3 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 GEGDIHENVDT(0.001)DLPGS(0.678)LGQS(0.223)EEKPVPAAPVPS(0.098)PVAPAPVPSR;GEGDIHENVDT(0.007)DLPGS(0.751)LGQS(0.24)EEKPVPAAPVPS(0.002)PVAPAPVPSR 78.273 3.0958e-12 11166600.0 14055.2 36637.0 36284.0 30817.0 47190.0 45283.0 51378.0 49769.0 46707.0 48686.0 True False 13854.770270591987 36552.16927747055 33300.86958029036 33083.38498249836 44414.376979109635 43346.35164982876 54038.10144551526 52081.4494306671 41446.36581348549 57101.31022998281 0.24263489252330872 0.6401283811221149 0.5831892376228647 0.579380487930151 0.7778171253903818 0.7591130829615957 0.9463548424347868 0.912088518125108 0.725839138306196 1.0 15.801236229176302 -4.927195818485037 0.3780017276864479 0.9326172185914259 1.1339386405474836e-18 0.7715228305696638 0.10072811109029028 2.68104451042499 0.3309442713543124 0.09031232729539235 1.1321549949446552 1.1825082558654611e-05 4.927195818485037 -0.9326172185914259 down GEGDIHENVDTDLPGSLGQSEEKPVPAAPVPS(ph)PVAPAPVPSR ddPTM_PC-9_AZD4547_30min_R2 3 GEGDIHENVDTDLPGSLGQSEEKPVPAAPVPSPVAPAPVPSR 42 1 Q9UK76;Q9UK76-3 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 GEGDIHENVDTDLPGS(0.004)LGQS(0.001)EEKPVPAAPVPS(0.993)PVAPAPVPS(0.002)R;GEGDIHENVDTDLPGS(0.003)LGQS(0.009)EEKPVPAAPVPS(0.976)PVAPAPVPS(0.012)R;GEGDIHENVDTDLPGS(0.015)LGQS(0.005)EEKPVPAAPVPS(0.954)PVAPAPVPS(0.026)R 90.338 4.7818e-17 189333400.0 101251.1 137457.3 140028.2 91591.5 123405.0 160254.0 162113.9 219988.0 174565.8 146386.3 True False 133446.84364628867 181887.6841009929 138171.3345751994 70476.49474956877 106272.34587535463 150233.29204657068 176541.72304376232 185993.90942133666 183792.99180485608 141261.36019352206 0.9446804381854469 1.2875968619572578 0.9781254717207207 0.49890851010509146 0.7523100848651466 1.063512993509035 1.2497523937324946 1.3166651458440788 1.3010846812820398 1.0 17.10800736770502 -7.04066291630053 3.9842780755509257 1.2391381973215383 0.8968685300952061 0.3604692048963495 0.20240895353630253 0.2718158988778772 9.184842486773432 0.08820924684702659 0.07013022036538884 9.106197886185897e-08 7.04066291630053 -0.34226966722633223 GEGDIHENVDTDLPGSLGQSEEKPVPAAPVPS(ph)PVAPAPVPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GEGDIHENVDTDLPGSLGQSEEKPVPAAPVPSPVAPAPVPSR 42 1 Q9UK76;Q9UK76-3 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 GEGDIHENVDTDLPGS(0.001)LGQS(0.001)EEKPVPAAPVPS(0.984)PVAPAPVPS(0.013)R;GEGDIHENVDTDLPGS(0.01)LGQS(0.003)EEKPVPAAPVPS(0.981)PVAPAPVPS(0.006)R;GEGDIHENVDT(0.001)DLPGS(0.008)LGQS(0.002)EEKPVPAAPVPS(0.988)PVAPAPVPS(0.001)R 83.712 1.2067e-13 134079400.0 204984.0 361040.0 361614.0 238246.0 329615.0 185603.0 316382.0 190314.0 209792.0 176159.0 True False 239683.7425814535 396881.665169764 370236.24918873224 224897.84902395378 265029.30691107595 175869.65194459225 286412.00655267906 185318.45915435147 212859.81111252957 208095.23222612342 1.1517983377966339 1.9072117170781635 1.7791673803771766 1.0807448427245658 1.2735962476213103 0.8451402276890527 1.3763506423897975 0.8905463963392398 1.0228961463241444 1.0 17.66688438558154 -5.770271822846075 24.982811409256453 1.0772272840593728 1.6421744080185197 0.5259003970175722 0.23561804745762618 132.10365515597786 373659.42846395256 0.06405711341479199 0.09664107857330088 1.6971810624243823e-06 5.770271822846075 0.5649471239591468 GEGDIHENVDTDLPGSLGQSEEKPVPAAPVPS(ph)PVAPAPVPSR ddPTM_PC-9_Lapatinib_30min_R1 2 GEGDIHENVDTDLPGSLGQSEEKPVPAAPVPSPVAPAPVPSR 42 1 Q9UK76;Q9UK76-3 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 GEGDIHENVDTDLPGS(0.003)LGQS(0.002)EEKPVPAAPVPS(0.989)PVAPAPVPS(0.007)R;GEGDIHENVDTDLPGSLGQSEEKPVPAAPVPS(0.995)PVAPAPVPS(0.005)R 92.444 1.9172e-17 156608000.0 73402.0 170877.0 165330.0 137878.0 207157.0 189606.0 222465.0 210118.0 175184.0 175406.0 True False 72355.2740197217 170481.34480515166 151737.2055922559 148018.00806752473 194972.43254633225 181496.99337317355 233983.1491703953 219880.84935347122 155452.93315069776 205724.693386197 0.35170923251246583 0.8286868338411632 0.7375741000979741 0.7194955823298164 0.9477347096117428 0.8822324164676626 1.1373605439340724 1.068811165710183 0.7556357508277992 1.0 17.65035544714101 -4.525970844696072 0.535063051617753 0.9888790851521543 8.306962140870344e-14 0.6214034555871228 0.13057866021461004 3.8103888772226746 0.6829709779302623 0.07552341599191119 2.4959604330136305 2.9787163915984523e-05 4.525970844696072 -0.9888790851520712 GEGDIHENVDTDLPGSLGQSEEKPVPAAPVPS(ph)PVAPAPVPSRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GEGDIHENVDTDLPGSLGQSEEKPVPAAPVPSPVAPAPVPSRR 43 2 Q9UK76;Q9UK76-3 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 GEGDIHENVDT(0.001)DLPGS(0.006)LGQS(0.006)EEKPVPAAPVPS(0.982)PVAPAPVPS(0.004)RR 59.917 3.193e-06 4611000.0 13587.0 18374.0 17535.0 17140.0 22101.0 17775.0 20123.0 15042.0 19169.0 14616.0 True False 15887.010744517695 20198.049290464358 17953.100901857826 16179.701368629749 17770.467703355993 16842.84770890085 18216.803762096315 14647.163438316404 19449.310360814874 17265.76509980766 0.9201451921000984 1.1698322763981865 1.0398091713907207 0.9370972716876583 1.029231406811735 0.9755054358459028 1.055082335291313 0.8483356140689978 1.126466753623999 1.0 14.075626645466286 -5.538315735935338 24.1342270155039 0.992316046967784 1.0599467339340678 0.05018593246880132 0.08890398436882423 335.6847063639789 524807.5461565873 0.022315732737835336 0.03867017374064498 2.895237958746494e-06 5.538315735935338 0.06763068696628383 GEGEEDHES(ph)PSSGR ddPTM_PC-9_AZD4547_30min_R2 1 GEGEEDHESPSSGR 14 0 Q9NTX7-2;Q9NTX7 Q9NTX7-2 RNF146 E3 ubiquitin-protein ligase RNF146 1 GEGEEDHES(0.91)PS(0.068)S(0.022)GR 72.209 0.023313999999999998 778760.0 0.0 417.71 497.43 597.44 1062.6 792.26 819.77 1211.4 529.31 689.2 True False 0.0 552.726588735744 490.83375318501163 459.7094383559868 915.0763318111246 742.7198569571806 892.7279418950808 1024.2059652026815 557.288245992218 665.0713177761537 0.0 0.8310786737637931 0.7380167210130898 0.691218258957776 1.3759070754561038 1.116752199509469 1.3423040778245539 1.539994189837252 0.8379375731548044 1.0 9.377365243599352 -5.206330963393589 0.7572689279674981 1.2340395891664755 5.416767561008443e-22 0.6175956927850608 0.2590399844632552 1.1363828534525848 0.7398610247879338 0.11005984105824405 1.0755948696785835 6.218262285897207e-06 5.206330963393589 -1.2340395891664755 GEGEEDHES(ph)PSSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GEGEEDHESPSSGR 14 0 Q9NTX7-2;Q9NTX7 Q9NTX7-2 RNF146 E3 ubiquitin-protein ligase RNF146 1 GEGEEDHES(0.592)PS(0.382)S(0.027)GR;GEGEEDHES(0.904)PS(0.076)S(0.02)GR;GEGEEDHES(0.931)PS(0.067)S(0.002)GR;GEGEEDHES(0.86)PS(0.111)S(0.028)GR 112.12 0.0024054000000000002 1841720.0 3495.6499999999996 8139.960000000001 8694.48 3858.31 5826.02 2986.34 4374.14 2494.66 2927.63 4103.969999999999 True False 4087.394502765384 8948.041433678469 8901.789377199022 3642.1413995097955 4684.45320343451 2829.731073248888 3959.789793168814 2429.177818310757 2970.4410502181877 4847.987273991356 0.8431116403076333 1.8457229625340026 1.8361824967973077 0.7512687624097689 0.9662676361726074 0.5836919350902433 0.8167904677498694 0.5010693471377062 0.6127163464628113 1.0 12.243170196390926 -5.775743999144181 24.789677560934596 0.731801165745122 1.542077344367293 0.5760542978779695 0.2985152838858859 133.74782326712142 231782.5750189024 0.08341371633905269 0.12438715495776734 1.6759304851938567e-06 5.775743999144181 0.810276178622171 GEGESPQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GEGESPQAR 9 0 P18206;P18206-2 P18206 VCL Vinculin 0 99.13600000000001 0.019527000000000003 1541400.0 5388.0 8228.4 10803.0 5627.5 13096.0 8527.1 6531.1 7948.4 9632.3 9803.5 False True 6300.081982149209 9045.261172398876 11060.584490605654 5312.209419601161 10529.9328104226 8079.923864898369 5912.426926930737 7739.76292202594 9773.154164978729 11580.796945536704 0.5440110911000207 0.7810568836443474 0.9550797361030026 0.45870845025467033 0.9092580467427062 0.6977001585380885 0.5105371378788759 0.6683273144693969 0.8439103293962296 1.0 13.499446916970909 -8.519932742992841 3.355485450061318 0.9988495074923341 0.6970184701563344 0.2924103161143138 0.15327277119327468 0.27876165393498464 8.120170201487857 0.14585928344793353 0.03860897241351899 3.0204194413869538e-09 8.519932742992841 -0.3018310373359997 GEGPDVDVNLPK ddPTM_PC-9_Lapatinib_30min_R1 2 GEGPDVDVNLPK 12 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ; 107.85 0.0069237 13438000.0 112728.0 132166.0 106574.0 100643.0 115715.0 96827.0 108610.0 108234.0 93048.0 99737.0 False True 111120.47804821655 131859.97774725498 97811.89710753676 108044.62195520574 108908.87120444323 92685.93492476136 114233.29436718846 113262.9467676429 82567.95440112174 116976.40755880142 0.9499392259277476 1.1272356580190916 0.8361677294489396 0.9236445554279321 0.931032790947159 0.7923472506895907 0.9765498595070629 0.9682546175878085 0.7058513432259123 1.0 16.835858062963077 -5.269241047107417 24.966712140802066 0.8926204819553772 1.0385874446157743 0.2758390395988951 0.09517057987925305 636.1450054102172 2035780.6870847254 0.02363143412375989 0.050681911421266546 5.379711087386204e-06 5.269241047107417 0.1459669626603971 GEGPEVDVNLPK ddPTM_PC-9_Lapatinib_30min_R1 2 GEGPEVDVNLPK 12 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ; 139.86 0.0003395 17566500.0 114254.0 123846.0 119695.0 129299.0 122541.0 108392.0 132677.0 114829.0 118718.0 122177.0 False True 112624.71700838246 123559.2421960756 109854.13913606171 138808.07978881968 115333.37930487562 103756.32683409318 139546.36586645318 120164.37454387426 105346.72868403814 143295.1316593805 0.7859633171355527 0.8622710399525779 0.7666285509070213 0.9686866412096485 0.8048659990698683 0.7240743326907086 0.9738388474924722 0.8385796024774297 0.7351731176356531 1.0 17.128630070427818 -10.699578250744446 4.669443271468231 1.0000239098078652 0.8329173341025927 0.2782356489019091 0.08244535748847907 2.0025915443804175e-05 3.530779341574603e-06 0.07789946877153489 0.01889069440392137 1.9972008823685786e-11 10.699578250744446 -0.16710657570527243 GEGPGEAGGPLT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 GEGPGEAGGPLTPR 14 0 P50548;P50548-2 P50548 ERF ETS domain-containing transcription factor ERF 1 GEGPGEAGGPLT(1)PR;GEGPGEAGGPLT(1)PR;GEGPGEAGGPLT(1)PR 123.28 0.00011158 73151200.0 68299.0 66385.0 99447.0 122381.0 98163.0 87600.0 73963.0 86790.0 63634.0 84888.0 True False 90016.66129254762 87842.65302057021 98128.26780248454 94167.9512176018 84534.76186671885 82122.35815193121 80545.56371468322 73378.59973579398 66997.56332861414 81916.09695789615 1.098888553477042 1.0723491021028533 1.197911905555281 1.1495658938194155 1.0319676474596764 1.0025179568081848 0.9832690607327474 0.895777538980033 0.8178803167715626 1.0 16.321859356683838 -6.942903585926134 1.1628639742349578 0.9005693025138771 1.1288902960106775 0.7238484498971731 0.056508883656716094 0.2513396045142014 0.7045008714878714 0.0332014166421486 0.02518618113833419 1.1405029529494643e-07 6.942903585926134 0.22832099349680035 GEGPGEAGGPLT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GEGPGEAGGPLTPR 14 0 P50548;P50548-2 P50548 ERF ETS domain-containing transcription factor ERF 1 GEGPGEAGGPLT(1)PR;GEGPGEAGGPLT(1)PR 128.73 6.0589e-05 24037700.0 25332.0 18640.2 40170.0 23545.6 51530.0 59587.0 70396.0 73055.0 55053.0 49552.0 True False 29620.207270193743 20490.675867209833 41127.805145573344 22226.416367865142 41433.066411200125 56462.15282308158 63727.58125709551 71137.38365817076 55858.0459749565 58535.385346583804 0.5060222478218026 0.3500562223326287 0.7026144083968794 0.37970906377850133 0.7078293952602843 0.9645815516336527 1.0887018318879953 1.2152885513091172 0.9542611814071955 1.0 15.83702139451346 -6.681734888978464 2.1851338903122066 1.0792760593474438 0.4888270810500292 0.851163571122696 0.11104404912793728 0.10525100964664005 1.0299941942395454 0.04078217419365719 0.03958496934393714 2.0809666061421024e-07 6.681734888978464 -0.5904489782974145 GEGPGEAGGPLT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 GEGPGEAGGPLTPR 14 0 P50548;P50548-2 P50548 ERF ETS domain-containing transcription factor ERF 1 GEGPGEAGGPLT(1)PR 156.2 0.00085564 18338000.0 9444.9 8307.6 13884.0 6375.6 18456.0 26762.0 25096.0 31153.0 24301.0 24462.0 True False 9310.213994017471 8288.364262617419 12742.51111378986 6844.482892378123 17370.45436589209 25617.451645269008 26395.34808432891 32600.48210961787 21563.965479125407 28690.224106433852 0.3245082352608613 0.28889158313541136 0.44414121920129307 0.23856498530603082 0.6054485423833522 0.8928982760899463 0.9200119171745922 1.1362923478282323 0.7516136994653044 1.0 14.808271616947696 -6.60630602742095 2.332214075770038 0.9586079517847063 0.3287590426858209 0.8886668788148347 0.10285090199606264 0.08673718001953067 0.9593203318342369 0.03587459734935563 0.03652558663089316 2.4756769467529224e-07 6.60630602742095 -0.6298489090988854 down GEGS(ph)PSEATR ddPTM_PC-9_AZD4547_30min_R2 1 GEGSPSEATR 10 0 Q5T0Z8 Q5T0Z8 C6orf132 Uncharacterized protein C6orf132 1 GEGS(0.951)PS(0.049)EATR 82.48899999999999 0.014844 9431200.0 48553.0 55141.0 62568.0 69101.0 67744.0 76286.0 60245.0 75472.0 62983.0 65273.0 True False 63991.84403486241 72964.2499089742 61738.30743879505 53170.83204980755 58338.91494655823 71515.8243604819 65606.68828997054 63809.53657402739 66312.15279765707 62987.812137554974 1.0159400979845878 1.1583867963159657 0.9801627544066586 0.8441447677796974 0.9261937026667267 1.1353914659601632 1.0415775062435313 1.0130457688334675 1.0527775223060976 1.0 15.942785080070722 -6.74594104235044 24.999966951772233 1.0489375349282541 0.9865099490891116 0.13342697025446215 0.08098165796924979 605.5419891933707 976782.6256335067 0.030034130710503412 0.02993334364658612 1.794977287443702e-07 6.74594104235044 -0.06242758583914254 GEGS(ph)PSEATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GEGSPSEATR 10 0 Q5T0Z8 Q5T0Z8 C6orf132 Uncharacterized protein C6orf132 1 GEGS(0.78)PS(0.219)EAT(0.001)R;GEGS(0.937)PS(0.063)EATR 91.70100000000001 0.007903199999999999 13318700.0 51715.0 69150.0 73177.0 63912.0 74092.0 52111.0 62854.0 49599.0 42615.0 47271.0 True False 60469.3280821913 76014.75500357084 74921.81720531775 60331.217845499676 59574.20447387236 49378.20742382741 56900.01409644697 48297.07880448448 43238.163755340734 55840.858102969876 1.0828867989579705 1.361274836847968 1.3417024693131114 1.0804135161076793 1.0668568947135133 0.884266630229331 1.0189674018175727 0.864905741874977 0.774310517857911 1.0 15.769033491071713 -6.2825260731912556 1.438143713999443 0.9029030696587281 1.268097861905993 0.6753344692808274 0.10278567311055788 0.23266491428328945 0.9665794187112173 0.039347857374682806 0.05357784596117541 5.217637788233337e-07 6.2825260731912556 0.3651947922472649 GEGS(ph)PSEATR ddPTM_PC-9_Lapatinib_30min_R1 2 GEGSPSEATR 10 0 Q5T0Z8 Q5T0Z8 C6orf132 Uncharacterized protein C6orf132 1 GEGS(0.955)PS(0.045)EATR;GEGS(0.969)PS(0.031)EATR 69.346 0.038623000000000005 11715000.0 52641.0 75034.0 81551.0 78273.0 88523.0 69720.0 88373.0 90948.0 84680.0 72791.0 True False 51890.329686822915 74860.26338307523 74846.19157596346 84029.4575310736 83316.25118291417 66738.23812525808 92948.5215275901 95173.77610199766 75142.44668006821 85372.82736208946 0.6078084946951782 0.8768628812721924 0.8766980535682662 0.9842646674296229 0.9759106469503137 0.7817269286655225 1.0887365968725629 1.1148017354320445 0.8801681870200759 1.0 16.381489338529654 -4.252164169936836 0.9534029494695627 0.9785980304553337 1.6190138826706327e-22 0.5770813000437006 0.09241992378698856 3.720202478385936 1.3329069825026516 0.031403855050565525 4.78251188790359 5.595460445742372e-05 4.252164169936836 -0.9785980304553337 GEGS(ph)PSEATRLPTQGAR ddPTM_PC-9_Lapatinib_30min_R1 1 GEGSPSEATRLPTQGAR 17 1 Q5T0Z8 Q5T0Z8 C6orf132 Uncharacterized protein C6orf132 1 GEGS(0.467)PS(0.267)EAT(0.267)RLPTQGAR 91.932 0.01029 4879900.0 25253.0 11665.0 18306.0 13038.0 9079.0 12494.0 8255.0 8492.9 14683.0 8421.1 True False 24892.887589166974 11637.990409195467 16800.95134320349 13996.858013492994 8544.99107000077 11959.66074493652 8682.403507974785 8887.511138855773 13029.245921155436 9876.675914589576 2.520371003810688 1.1783306964648017 1.7010734672771384 1.417162832367233 0.8651687211259331 1.210899380354276 0.8790815435332203 0.8998484121289599 1.3191934243695254 1.0 13.269809855980638 -1.5228787452812387 0.6480987418115383 1.0490000791859675 114.97866404684044 0.7040175789376495 0.26110461413114733 121.78853454155323 0.7918188388702628 0.10839033295379398 19898.89313152391 0.029999999999937754 1.5228787452812387 113.92966396765446 up GEHGFIGCR ddPTM_PC-9_AZD4547_30min_R2 6 GEHGFIGCR 9 0 Q16658;C9JFC0;A0A0A0MSB2;C9JPH9 Q16658 FSCN1 Fascin 0 ;;;;; 113.18 0.0017783 93186000.0 42958.1 34335.2 55390.299999999996 64586.3 62180.7 53833.2 41758.1 56546.0 47388.200000000004 52117.700000000004 False True 56617.882216011865 45433.38193856864 54655.78843062091 49696.926383387894 53547.98312201013 50467.00149388746 45474.490003841325 47808.11499781314 49893.04350707226 50293.075186393275 1.1257590037232355 0.9033725173930223 1.086745804030849 0.98814650325525 1.0647188091711177 1.0034582555719567 0.9041898876794948 0.9505904107201535 0.9920459888794145 1.0 15.618072149719364 -7.011960231558448 23.67922322941568 0.9570512324628196 1.0276334960112374 0.23142375800526094 0.06115840717262753 417.25321042337754 826090.4979757362 0.021097676064984992 0.017278543863860834 9.728363025333393e-08 7.011960231558448 0.07058226354841779 GEHGFIGCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 GEHGFIGCR 9 0 Q16658;C9JFC0;A0A0A0MSB2;C9JPH9 Q16658 FSCN1 Fascin 0 ;;;;; 107.69 0.0020859000000000003 66376900.0 40656.5 49939.2 63320.799999999996 52943.6 59988.4 56788.9 64800.399999999994 55404.7 55429.399999999994 44741.0 False True 47538.84244752218 54896.83373932497 64830.60801747123 49977.34173746713 48234.10365033258 53810.79011285513 58662.03699773128 53950.38533113212 56239.9501128777 52852.18913043886 0.8994678031253657 1.0386860912012543 1.2266399762074134 0.945605897498841 0.9126226263077036 1.0181373940831562 1.1099263429364061 1.020778632233812 1.0640987826271087 1.0 15.689675608626093 -7.026696533042521 24.47930429028635 1.05237526254542 1.0105379569278294 0.048549612475270676 0.08990197246887616 2294.23514999279 2103683.2074451675 0.03648910332714647 0.028354098944324755 9.403801796782115e-08 7.026696533042521 -0.04183730561759047 GEHGFIGCR ddPTM_PC-9_Lapatinib_30min_R1 5 GEHGFIGCR 9 0 Q16658;C9JFC0;A0A0A0MSB2;C9JPH9 Q16658 FSCN1 Fascin 0 ;;;; 118.33 0.0015140999999999998 93789200.0 66642.9 66724.8 69607.4 53320.399999999994 61036.1 61376.3 59376.5 59201.6 67659.6 46744.299999999996 False True 65692.56002518881 66570.30282515947 63884.54826433422 57241.760087640134 57446.07659958964 58751.37872414336 62450.72463855424 61952.32246206637 60039.06336082607 54823.9899721354 1.1982447840548895 1.2142549795991535 1.1652663058052486 1.0441005865631738 1.0478273585849358 1.0716363174953898 1.1391130902784559 1.1300221398251746 1.0951239300777134 1.0 15.742519707777747 -5.593755963556846 4.819957485463109 1.0825002426839623 1.203043035985243 0.6556929658662523 0.03934345370584709 0.13188895469137413 5.777104631398676 0.011501212682040258 0.020700858520432498 2.5482617560353755e-06 5.593755963556846 0.12054279330128082 GEHPGLSIGDVAK ddPTM_PC-9_AZD4547_30min_R2 1 GEHPGLSIGDVAK 13 0 Q5T7C4;P09429;B2RPK0 Q5T7C4 HMGB1;HMGB1P1 High mobility group protein B1;Putative high mobility group protein B1-like 1 0 92.039 0.0040420000000000005 3164100.0 31515.0 35585.0 40095.0 51916.0 42366.0 48166.0 38905.0 45062.0 37308.0 36048.0 False True 41536.11444727799 47087.1553473976 39563.31410239239 39947.56829420428 36484.21219039158 45154.17240577533 42367.469631028405 38098.703321746114 39280.02471420847 34785.97049215726 1.194047883661679 1.3536248861596005 1.1373353551056513 1.1483815954828895 1.0488197303167723 1.2980569973160774 1.2179470353020752 1.0952318645338852 1.1291915723054047 1.0 15.086217950497193 -14.522878732655043 0.08182075459263334 0.39103275924044956 1.3585107083034667 0.3599891804195262 0.08188646691221324 290.9118122837827 1.6735566034847227 31.575027208767168 2.7808319320396184 3.0000000872124478e-15 14.522878732655043 0.9674779490630171 GEHPGLSIGDVAK ddPTM_PC-9_Lapatinib_30min_R1 2 GEHPGLSIGDVAK 13 0 Q5T7C4;P09429;B2RPK0 Q5T7C4 HMGB1;HMGB1P1 High mobility group protein B1;Putative high mobility group protein B1-like 1 0 ; 133.15 3.9826e-05 11058700.0 116647.0 133548.0 143588.0 144723.0 142862.0 128876.0 146034.0 142471.0 135550.0 134305.0 False True 114983.59238956012 133238.7778111648 131782.7489057084 155366.41220177515 134459.13803749857 123364.27390462933 153594.9259701502 149090.72277595624 120282.93159522038 157519.4402998367 0.7299644549948248 0.8458560896200882 0.8366126025769344 0.9863316674185532 0.8536034522567941 0.7831685642724902 0.9750855239060257 0.9464909378306801 0.7636069006229518 1.0 17.26517036459488 -4.535700782076113 1.3145008690636137 0.893783793000101 0.5754356301373711 0.2861542857925956 0.07913169717641268 3.1391717439524935 3.172127394921354 0.0228578714945232 1.564110498263473 2.912723219607612e-05 4.535700782076113 -0.31834816286272993 GEIKDSSPSSSPS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 GEIKDSSPSSSPSPK 15 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 GEIKDSSPS(0.002)S(0.002)S(0.005)PS(0.991)PK 56.303999999999995 0.031629000000000004 7929900.0 63992.0 23289.0 36916.0 51704.0 51207.0 38235.0 37513.0 32065.0 28466.0 35181.0 True False 84340.12488371313 30816.713808783 36426.46971951409 39784.44161883694 44097.791947160025 35844.15940569737 40851.5843276897 27110.091030397885 29970.654645509203 33949.323898262985 2.48429468393709 0.9077268784831304 1.0729659839080874 1.1718772879854762 1.298929901499932 1.0558136448641127 1.203310688899459 0.7985458300035534 0.8828056409996032 1.0 15.051095222993368 -4.7578318931345915 24.99999973670869 1.0555427884379287 2.484296700542505 0.89641288803909 0.146877660745269 32.84185874261494 227560.99713590633 0.0394169104425764 0.28343266555026025 1.7464980571981988e-05 4.7578318931345915 1.4287539121045763 GEIKDSSPSSSPS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GEIKDSSPSSSPSPK 15 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 GEIKDSSPSSS(0.005)PS(0.994)PK 63.443000000000005 0.018484 3949800.0 43097.0 15525.0 13259.0 24201.0 23750.0 24383.0 21515.0 26349.0 25111.0 17273.0 True False 50392.47089545002 17066.2193988494 13575.144845037512 22845.096430700614 19096.357990801545 23104.3125561817 19476.943444889046 25657.366669073203 25478.200869655288 20404.45816700723 2.4696794437272334 0.8363965981926657 0.6653028830232649 1.1196129906374945 0.9358914524708721 1.132316887176155 0.9545435260016892 1.257439254650712 1.248658536341435 1.0 14.316596780410082 -4.757121485694057 24.99936507347868 1.016112247591597 2.4696815887568855 0.862706139851802 0.1738917705168613 47.441718877945384 274638.64218693937 0.04646866682227982 0.3545131358265418 1.7493572704573093e-05 4.757121485694057 1.4535693411652886 GEIKDSSPSSSPS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 GEIKDSSPSSSPSPK 15 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 GEIKDSSPS(0.001)S(0.005)S(0.028)PS(0.966)PK;GEIKDSSPSS(0.001)S(0.005)PS(0.994)PK 84.499 0.0028718000000000003 13032200.0 191034.0 85671.0 79262.0 77789.0 75776.0 71656.0 45275.0 43880.0 84082.0 56671.0 True False 188309.8201286554 85472.6340631104 72745.38432016812 83509.86255649709 71319.00466134798 68591.43991829439 47619.11796772364 45918.82499181564 74611.79973728751 66466.50684063908 2.833153554769312 1.2859504452075485 1.0944667890338116 1.2564202111105578 1.0730066623230752 1.0319699827576327 0.7164378004984651 0.6908566009330261 1.1225473292312125 1.0 16.020339914337 -2.77097583200983 1.1539224376742359 0.9599706676417736 199.99999999893333 0.9128233271060847 0.16887097195048284 47.04287645936659 0.7810579887849518 0.05583773743019215 24055.59240577187 0.0016944320910275885 2.77097583200983 199.04002933129155 up GEIPS(ph)PQLTRPK ddPTM_PC-9_Lapatinib_30min_R1 1 GEIPSPQLTRPK 12 1 Q8IWZ3-6;H7C0V5 Q8IWZ3-6 ANKHD1;ANKHD1-EIF4EBP3 Ankyrin repeat and KH domain-containing protein 1 1 GEIPS(0.972)PQLT(0.028)RPK 62.376999999999995 0.0245 13207000.0 47102.0 77613.0 72351.0 75654.0 72275.0 57779.0 63904.0 61910.0 59071.0 44930.0 True False 46430.316842551074 77433.29186702834 66402.58006293667 81217.84753434574 68023.92659811713 55307.926859427476 67212.63643532661 64786.56461356666 52417.80193479353 52696.09063453819 0.881096041157171 1.4694314309585015 1.2601044833374213 1.5412499590835635 1.2908723546473624 1.0495641364176915 1.2754767123326973 1.2294377786557114 0.9947189877580357 1.0 15.685408316148793 -6.666408770814057 7.312165336085155 1.1349854434863038 1.312818511009521 0.17889851403289925 0.18436084118587207 0.4070608543791646 27.059821038654764 0.05972673159324439 0.05959479014867946 2.1557144317696872e-07 6.666408770814057 0.17783306752321715 GEIPSPQLT(ph)RPK ddPTM_PC-9_AZD4547_30min_R2 1 GEIPSPQLTRPK 12 1 Q8IWZ3-6;H7C0V5 Q8IWZ3-6 ANKHD1;ANKHD1-EIF4EBP3 Ankyrin repeat and KH domain-containing protein 1 1 GEIPS(0.055)PQLT(0.945)RPK 64.374 0.031825 15721000.0 18465.0 32123.0 47944.0 50929.0 45982.0 45862.0 42169.0 57943.0 47814.0 52466.0 True False 24336.485904140514 42506.13155049749 47308.23123394688 39188.10589520631 39598.19300709496 42994.24188999846 45921.95930782253 48989.24074767949 50341.35042578437 50629.18130940751 0.48068100796286234 0.8395579476336376 0.9344064037858822 0.7740221129731104 0.7821219301394696 0.8491988370748079 0.9070255161185014 0.9676087876731417 0.9943149212335839 1.0 15.62768153513023 -3.542604858933077 0.30590350730519117 0.9786611919078303 2.534890299700622e-41 0.6099540723662773 0.09143383977415602 13.658278908703792 0.5729137741078983 0.10347867556212959 5.741755293787734 0.0002866785116447213 3.542604858933077 -0.9786611919078303 GEIQGLVS(ph)ALQEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GEIQGLVSALQEVR 14 0 A0A590UK13 A0A590UK13 1 GEIQGLVS(1)ALQEVR 61.18600000000001 0.030032 2998200.0 14019.0 14470.0 17348.0 20571.0 21044.0 16648.0 18790.0 16858.0 19799.0 14908.0 True False 16392.139812128764 15906.485971101505 17761.64211265637 19418.473562081836 16920.579265618006 15774.949572870966 17010.075172180586 16415.495362527454 20088.522918971983 17610.702388336933 0.9308055664483214 0.9032283676337588 1.0085709088139152 1.1026518496469588 0.9608122886015054 0.8957592505406409 0.9658941930360413 0.9321317798998733 1.1406996993076233 1.0 14.104164830567647 -8.248365528160996 24.926057674161612 1.0703498587730558 0.9645493145667151 0.30873955003771103 0.06450276180295884 847.4156614453302 1615655.1756507223 0.04665794494999279 0.017399660374403342 5.644616901726459e-09 8.248365528160996 -0.10580054420634066 GEIQGLVS(ph)ALQEVR ddPTM_PC-9_Lapatinib_30min_R1 1 GEIQGLVSALQEVR 14 0 A0A590UK13 A0A590UK13 1 GEIQGLVS(1)ALQEVR 62.732 0.026726 4624200.0 22953.0 11943.0 17504.0 17703.0 13790.0 13286.0 10831.0 8906.7 17434.0 10365.0 True False 22625.686010935322 11915.346717275726 16064.888687393975 19004.9376754768 12978.899312183132 12717.788751178692 11391.776183509983 9320.537797506933 15470.399331841174 12156.576439505638 1.8611889723662547 0.9801564426110975 1.32149777261198 1.5633462077132023 1.0676442810004603 1.0461653257778452 0.9370875295522959 0.7667074561566254 1.2725950771441288 1.0 13.56944937073477 -6.4044638723488525 5.259851442954901 0.9926900868672709 1.3899816410251666 0.42281634620557196 0.23688734340576514 0.23869451615151768 9.348022239610039 0.07280250197490978 0.08245096210456815 3.940362049676305e-07 6.4044638723488525 0.39729155415789574 GELIPIS(ph)PSTEVGGSGIGTPPSVLKR ddPTM_PC-9_Lapatinib_30min_R1 1 GELIPISPSTEVGGSGIGTPPSVLKR 26 1 P10244-2;P10244 P10244-2 MYBL2 Myb-related protein B 1 GELIPIS(0.631)PS(0.184)T(0.184)EVGGSGIGTPPSVLKR 60.33 0.025043 0.0 26722.0 13141.0 13385.0 13259.0 16661.0 18395.0 14015.0 11609.0 17275.0 11680.0 True False 26340.939379785374 13110.572821880638 12284.536967594166 14234.111090727381 15681.03273678631 17608.288730839377 14740.628124078336 12148.396520738104 15329.307586185409 13698.87243737828 1.9228545634100787 0.9570548876787531 0.8967553368899905 1.0390717305965027 1.1446951424994347 1.285382341600174 1.0760468200183801 0.8868172600534917 1.119019660651659 1.0 13.741769528505372 -4.757804345615421 24.99999622117406 1.0482280360145615 1.9228557998549767 0.8410611542099848 0.1144785081333272 43.10292588608993 296396.844452739 0.03132182506059847 0.22601677525473507 1.746608841968956e-05 4.757804345615421 0.8746277638404152 GELS(ph)PSFLNPPLPPSIDDR ddPTM_PC-9_AZD4547_30min_R2 3 GELSPSFLNPPLPPSIDDR 19 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 GELS(0.944)PS(0.056)FLNPPLPPSIDDR;GELS(0.5)PS(0.5)FLNPPLPPSIDDR;GELS(0.797)PS(0.203)FLNPPLPPSIDDR 112.62 0.00010426 3856500.0 22586.6 23055.4 32021.6 33160.7 30028.6 30202.800000000003 28332.5 33438.4 28131.8 29359.899999999998 True False 29768.66896953482 30507.60717707997 31596.972661458236 25516.012942707846 25859.647221366024 28314.214141451444 30854.037612674758 28271.263617990197 29618.78951579202 28332.018837458054 1.0507076513085385 1.0767890333584542 1.1152390107719239 0.9006069454172769 0.9127357767804642 0.9993715698090999 1.0890165571922577 0.9978555986491322 1.0454175428061172 1.0 14.790145786172525 -5.733866569084751 24.99999968543659 0.9930829130628793 1.0804996243693563 0.3618753619371765 0.05400741360277941 272.55088509252505 247117.2290977108 0.016274924294489575 0.028180738896882065 1.8455823614920493e-06 5.733866569084751 0.08741671130647699 GELS(ph)PSFLNPPLPPSIDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GELSPSFLNPPLPPSIDDR 19 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 GELS(0.875)PS(0.125)FLNPPLPPSIDDR;GELS(0.752)PS(0.248)FLNPPLPPSIDDR 112.55 0.00046929 1542900.0 15445.8 16188.2 14642.1 16071.2 17127.7 13668.0 13335.9 10936.0 14194.0 12586.0 True False 18060.468871544217 17795.25751191329 14991.223194473472 15170.782767533396 13771.65013722321 12951.226018861138 12072.627008445079 10648.941587649802 14401.560397590192 14867.74216927882 1.2147418663785092 1.1969038277165975 1.008305297723672 1.0203824222134246 0.926277169756114 0.8710956829492393 0.81200136987785 0.7162447038968489 0.9686447500648823 1.0 13.85989795441085 -5.546018132325509 0.8322382967220147 0.851596764540656 1.274451751596785 0.7049999374067948 0.08005008156926385 0.5187036845785442 0.5593821097146607 0.033913596205341685 0.16582973752280075 2.8443423501987064e-06 5.546018132325509 0.422854987056129 GELS(ph)PSFLNPPLPPSIDDR ddPTM_PC-9_Lapatinib_30min_R1 2 GELSPSFLNPPLPPSIDDR 19 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 GELS(0.988)PS(0.012)FLNPPLPPSIDDR;GELS(0.596)PS(0.404)FLNPPLPPSIDDR 98.882 0.00052929 2257700.0 9095.1 9731.2 9688.8 8120.1 9564.3 9432.6 8872.400000000001 8015.0 11613.7 7703.4 True False 8965.402206162931 9708.668004283152 8892.224263849559 8717.279241859527 9001.74667813728 9029.18968646456 9331.769459013383 8387.406160196047 10305.642808317309 9034.922425864712 0.9923053883116072 1.0745712632229887 0.9842059338985973 0.9648427325622795 0.9963280539484813 0.9993654910214016 1.0328555154274344 0.9283318400371664 1.1406454114995879 1.0 13.141296498778997 -8.261617241114152 24.99999953860802 1.0703226952952 0.9990195894969705 0.27173309880070884 0.048145821628339816 20.807292027218175 2923490.0133289313 0.03597931359883913 0.011569267747482341 5.474982796656165e-09 8.261617241114152 -0.07130310579822963 GELSPS(ph)FLNPPLPPSIDDR ddPTM_PC-9_Lapatinib_30min_R1 2 GELSPSFLNPPLPPSIDDR 19 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 GELS(0.219)PS(0.781)FLNPPLPPSIDDR;GELS(0.43)PS(0.569)FLNPPLPPS(0.001)IDDR 130.56 3.8635e-05 4504600.0 8210.8 9212.9 9155.9 8328.2 9676.5 11094.400000000001 9545.599999999999 9117.6 9521.5 7335.5 True False 8093.7124863236895 9191.568096088884 8403.137244796068 8940.683610060782 9107.347294730971 10619.918374309565 10039.824461020486 9541.236981435235 8449.088404160017 8603.43140106065 0.9407539979136555 1.0683607118615168 0.9767192708435044 1.0391997324414715 1.0585715013207633 1.2343817111159063 1.1669558334344077 1.1090036680316844 0.98206029783865 1.0 13.070696465167288 -6.32284013921784 3.0349078627588386 1.111420553943222 1.006130020353453 0.22971302962714113 0.07627405316629898 0.36066330336569785 6.5756565712499295 0.02541456317924019 0.030361281819214898 4.7551022574390496e-07 6.32284013921784 -0.10529053358976914 GELSPS(ph)FLNPPLPPSIDDRDLSTEEVR ddPTM_PC-9_AZD4547_30min_R2 1 GELSPSFLNPPLPPSIDDRDLSTEEVR 27 1 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 GELS(0.186)PS(0.814)FLNPPLPPSIDDRDLSTEEVR 96.50399999999999 1.2857000000000002e-09 7235600.0 16998.0 14252.0 20632.0 34227.0 27031.0 24490.0 19161.0 29549.0 19253.0 20016.0 True False 22403.010419636088 18858.680286949846 20358.40619929068 26336.49395187863 23278.212239023625 22958.636428547885 20866.291880224522 24982.881018469554 20270.674274221485 19315.24593239625 1.159861515511999 0.9763624213202154 1.054007092146044 1.3635080828924928 1.20517296650003 1.1886277041930284 1.0803016411624766 1.2934280570855863 1.0494649845603443 1.0 14.237452426427586 -8.507381387584083 22.962322272605615 0.9999999468678687 1.1617088126251458 0.2239089018242909 0.10642844999042508 343.3549869265258 508745.4776442545 0.10805431324711524 0.027899503732284017 3.10898489776974e-09 8.507381387584083 0.16170886575727705 GELSPS(ph)FLNPPLPPSIDDRDLSTEEVR ddPTM_PC-9_Lapatinib_30min_R1 1 GELSPSFLNPPLPPSIDDRDLSTEEVR 27 1 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 GELS(0.241)PS(0.71)FLNPPLPPS(0.049)IDDRDLS(0.001)TEEVR 56.972 0.0015872 2443200.0 6939.3 6219.3 9451.9 6878.6 7600.6 8704.7 8328.1 6936.9 7798.1 6172.6 True False 6840.344309488237 6204.899592962654 8674.801267389112 7384.475190336937 7153.547651354538 8332.420272646783 8759.288268293738 7259.213698398491 6919.795860366559 7239.525685527503 0.9448608384887331 0.8570864808680541 1.1982554720029326 1.0200219615352981 0.9881238028694556 1.1509621810312904 1.2099257118189917 1.0027195169581822 0.9558355285899305 1.0 12.821679463523983 -5.2422287511512105 24.989872117067502 1.0696173514886245 0.9009736393001142 0.3568105090941306 0.08835862710375983 903.5084971943008 1175312.203690971 0.0232401030180593 0.06127267844667008 5.724944078807463e-06 5.2422287511512105 -0.16864371218851026 GELVGGLDIVK ddPTM_PC-9_Lapatinib_30min_R1 1 GELVGGLDIVK 11 0 O76003 O76003 GLRX3 Glutaredoxin-3 0 105.2 0.011926 2920800.0 30420.0 30012.0 32488.0 25756.0 30484.0 26851.0 25760.0 28608.0 28367.0 27660.0 False True 29986.205221655222 29942.50905793179 29816.962047306617 27650.182159497304 28690.991053849943 25702.645322738146 27093.726755351974 29937.232118638614 25172.00974224725 32440.99414536672 0.9243306505123828 0.9229837077051547 0.9191136965068972 0.8523222819744058 0.8844054200462177 0.7922890774421302 0.8351694351272385 0.9228210450176448 0.7759321317174357 1.0 14.98553041077585 -5.754853122014038 21.357643287805562 0.8593126212709751 0.9222269537535213 0.14627501442690183 0.060453964357430216 41.69371121146811 135189.42333232812 0.015525910535696151 0.025960523488946837 1.7585182426199424e-06 5.754853122014038 0.06291433248254619 GENLEHLR ddPTM_PC-9_Lapatinib_30min_R1 1 GENLEHLR 8 0 Q9BV40;B8ZZT4;C9JXZ5 Q9BV40 VAMP8 Vesicle-associated membrane protein 8 0 72.325 0.027687 1969300.0 29458.0 32665.0 22895.0 19621.0 22430.0 21238.0 20188.0 18156.0 26608.0 10965.0 False True 29037.92351806441 32589.366199431635 21012.661477255766 21063.99379373724 21110.7114990767 20329.70024819606 21233.23585935735 18999.59404173667 23611.126845338415 12860.285640055903 2.257953231429017 2.5341090479301336 1.6339187219767246 1.63791025979464 1.6415429711236906 1.580812496487262 1.651070314738752 1.4773850732023148 1.8359721942564704 1.0 13.65063506629895 -1.5228787452803476 0.3364175433427501 1.4246942736742896 12.77640184041939 0.6156890851480027 0.24696576542459742 38.864448917302866 0.5517431605356878 0.2140507171974965 276.11045592993696 0.029999999999999305 1.5228787452803476 11.351707566745102 GEPAAAAAPEAGAS(ph)PVEK ddPTM_PC-9_AZD4547_30min_R2 4 GEPAAAAAPEAGASPVEK 18 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 GEPAAAAAPEAGAS(1)PVEK;GEPAAAAAPEAGAS(1)PVEK;GEPAAAAAPEAGAS(1)PVEK;GEPAAAAAPEAGAS(1)PVEK 238.69 1.5374e-43 359268000.0 332509.0 483619.0 398172.0 254110.0 263348.0 433310.0 431516.0 504495.0 477914.0 320374.0 True False 438239.9453831497 639939.3840650019 392891.9791190368 195528.86546036386 226786.675917369 406215.0572010645 469920.0880427413 426536.88989179995 503175.5583592322 309157.80377425626 1.4175283302993957 2.0699441393764033 1.2708460673563406 0.632456509501979 0.7335628379704955 1.313940816767085 1.5200007320076319 1.3796736963601044 1.6275686792193855 1.0 18.237983897063522 -7.001030774829559 24.998405028307108 1.4139532209313341 1.2196882476673157 0.031244229923596656 0.39689569461118945 158.62327311762286 3847051.43134614 0.15972117516701062 0.13907163300178793 9.9762936764093e-08 7.001030774829559 -0.19426497326401848 GEPAAAAAPEAGAS(ph)PVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GEPAAAAAPEAGASPVEK 18 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 GEPAAAAAPEAGAS(1)PVEK;GEPAAAAAPEAGAS(1)PVEK;GEPAAAAAPEAGAS(1)PVEK;GEPAAAAAPEAGAS(1)PVEK;GEPAAAAAPEAGAS(1)PVEK 220.17 6.6714999999999994e-28 263681000.0 349228.0 623918.0 450569.0 339842.0 480680.0 281952.0 489813.0 252890.0 288512.0 321142.0 True False 408345.4028325921 685856.4557095848 461312.2737524477 320801.75452263 386494.2045902511 267165.9407718716 443414.36670097266 246251.9054591039 292730.94218892086 379362.502441326 1.0763989593192562 1.8079184191791928 1.2160196929948195 0.8456338000149257 1.0187991752032164 0.7042497322549499 1.1688407890802366 0.6491203107170309 0.7716391058818367 1.0 18.533217559049525 -5.596689664622068 4.0864464971820915 0.8771304524878596 1.4589157402407775 0.5195117738915478 0.22072601109770748 0.1470914778287331 4.770085661952056 0.057496359490278856 0.10619736662468411 2.531106011962174e-06 5.596689664622068 0.5817852877529179 GEPAAAAAPEAGAS(ph)PVEK ddPTM_PC-9_Lapatinib_30min_R1 4 GEPAAAAAPEAGASPVEK 18 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 GEPAAAAAPEAGAS(1)PVEK;GEPAAAAAPEAGAS(1)PVEK;GEPAAAAAPEAGAS(1)PVEK;GEPAAAAAPEAGAS(1)PVEK 240.94 6.716599999999999e-44 318748000.0 207129.0 398739.0 275558.0 288688.0 452174.0 438629.0 538859.0 537114.0 411555.0 441443.0 True False 204175.30247719304 397815.744343951 252902.68492464095 309919.0785549373 425578.0143282881 419869.8601641396 566758.4823626637 562070.2772710595 365201.3420337207 517745.83436417615 0.39435431233924445 0.7683610720547723 0.48846879711783886 0.598593089475142 0.821982498132359 0.8109574858864209 1.0946654608214823 1.0856104288339017 0.7053679967936594 1.0 18.981884515415054 -6.514654172340907 1.5642786379411664 0.9691223505197573 0.5628895359745091 0.6258133693387218 0.13892099083151643 0.25278123367143246 1.2597792076110779 0.05449364506485304 0.060385058723322664 3.057354708408992e-07 6.514654172340907 -0.4062328145452482 GEPNVS(ph)YICSR ddPTM_PC-9_Lapatinib_30min_R1 1 GEPNVSYICSR 11 0 P49841;P49841-2;A0A3B3ITW1;A8MT37;P49840 P49841 GSK3B;GSK3A Glycogen synthase kinase-3 beta;Glycogen synthase kinase-3 alpha 1 GEPNVS(0.613)Y(0.387)ICSR 112.83 0.0016385000000000002 35012000.0 34224.0 33975.0 41908.0 36819.0 31442.0 38539.0 33725.0 38105.0 44139.0 29655.0 True False 33735.95948408707 33896.33297491778 38462.486009558175 39526.79208458344 29592.643377350403 36890.77680879689 35471.11548230765 39875.497409141644 39167.60101572429 34780.82723719633 0.9699585134653776 0.9745694874866969 1.1058531111768526 1.1364534780906976 0.8508320741061205 1.0606641572154463 1.01984680353931 1.1464792696620172 1.1261262059298156 1.0 15.08600462607572 -7.738676160414283 23.279013575942642 1.1022270024436551 1.0185732125425122 0.13896427069143058 0.08288752190815424 184.88154445896794 189071.0831524955 0.03969065838731953 0.022886490912058632 1.8252562305379813e-08 7.738676160414283 -0.08365378990114292 GEPNVSY(ph)ICSR ddPTM_PC-9_AZD4547_30min_R2 5 GEPNVSYICSR 11 0 P49841;P49841-2;A0A3B3ITW1;A8MT37;P49840 P49841 GSK3B;GSK3A Glycogen synthase kinase-3 beta;Glycogen synthase kinase-3 alpha 1 GEPNVS(0.016)Y(0.973)ICS(0.011)R;GEPNVS(0.012)Y(0.988)ICSR;GEPNVS(0.206)Y(0.794)ICSR;GEPNVS(0.003)Y(0.997)ICSR;GEPNVS(0.212)Y(0.787)ICS(0.001)R 197.73 0.0001346 957318800.0 203331.0 210361.0 277929.0 352986.0 328453.0 286978.0 232008.0 306029.0 228800.0 264840.0 True False 267986.02845246595 278356.0794164367 274243.4798644175 271610.53127933556 282852.97046147176 269033.2202936636 252656.26254094904 258739.24989682244 240893.90089554235 255568.03221102172 1.048589786969877 1.0891662662511679 1.0730742710339278 1.0627719317221473 1.1067619373768975 1.0526872941273175 0.9886066749237696 1.012408506879226 0.9425822893867923 1.0 17.963347862149895 -7.1873212890275004 3.2535628856695658 0.9856702790430042 1.0762660779789028 0.7881617963311863 0.022149856041764157 0.1104803692913566 2.285714434655201 0.00891577114265874 0.006508020905577029 6.496489053005499e-08 7.1873212890275004 0.09059579893589864 GEPNVSY(ph)ICSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 GEPNVSYICSR 11 0 P49841;P49841-2;A0A3B3ITW1;A8MT37;P49840 P49841 GSK3B;GSK3A Glycogen synthase kinase-3 beta;Glycogen synthase kinase-3 alpha 1 GEPNVS(0.129)Y(0.871)ICSR;GEPNVS(0.137)Y(0.862)ICS(0.001)R;GEPNVS(0.003)Y(0.997)ICSR;GEPNVS(0.037)Y(0.963)ICSR;GEPNVS(0.367)Y(0.633)ICSR;GEPNVS(0.02)Y(0.98)ICSR 183.85 0.00010888 862297000.0 191624.0 151835.0 221808.0 216983.0 239975.0 201719.0 223499.0 193986.0 188450.0 155002.0 True False 224062.15845348206 166908.175357443 227096.7439315244 204826.14597837764 192953.62142495115 191140.50053399577 202327.55672736547 188894.07304515693 191205.72473762665 183102.63560484315 1.2236970686595376 0.9115552859525753 1.2402702079156613 1.1186411670251233 1.0538003496649146 1.0438981388913444 1.1049953271235917 1.031629459735426 1.0442543555204247 1.0 17.482293032074907 -7.7020148255907595 0.41799526822825545 0.998864074299024 1.1178340626776049 0.15674526858032234 0.08651424927138196 2.22723209192592 1.0154104840312075 0.09603768795028457 0.08217172348493867 1.986027118826417e-08 7.7020148255907595 0.11896998837858086 GEPNVSY(ph)ICSR ddPTM_PC-9_Lapatinib_30min_R1 3 GEPNVSYICSR 11 0 P49841;P49841-2;A0A3B3ITW1;A8MT37;P49840 P49841 GSK3B;GSK3A Glycogen synthase kinase-3 beta;Glycogen synthase kinase-3 alpha 1 GEPNVS(0.025)Y(0.975)ICSR;GEPNVS(0.044)Y(0.956)ICSR;GEPNVS(0.029)Y(0.971)ICSR 186.74 0.00036589 804759000.0 154192.0 149149.0 174292.0 131550.0 149832.0 151922.0 128223.0 133989.0 164488.0 108002.0 True False 151993.19380465063 148803.65465418703 159962.38454657586 141224.6258379357 141019.17634104588 145424.6502074792 134861.7595400426 140214.6180908927 145961.62930457108 126670.001796381 1.1999146731597594 1.1747347639055485 1.2628276804141172 1.114901901280075 1.1132799742730788 1.14805911537955 1.06467006889942 1.1069283658516431 1.1522983124228647 1.0 16.950715377891008 -1.5228787466194829 0.05581120231997635 0.788207222517608 1.8235314000657123 0.6131662737963082 0.04283045280093341 270.30561040271175 1.136518074851694 4.555955921799721 23.25203640174622 0.02999999990749512 1.5228787466194829 1.0353241775481044 GEQVSQNGLPAEQGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 GEQVSQNGLPAEQGSPR 17 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 GEQVSQNGLPAEQGS(1)PR;GEQVSQNGLPAEQGS(1)PR;GEQVSQNGLPAEQGS(1)PR;GEQVSQNGLPAEQGS(1)PR 188.54 1.8980000000000002e-08 155774700.0 68546.9 78907.8 90234.9 87244.0 78642.8 89712.0 103117.5 112638.2 92752.0 81346.4 True False 90343.38833590751 104413.20322386909 89038.32626756377 67131.24370636338 67724.60469354023 84102.29445806005 112294.75773493318 95232.5543583395 97654.6813630391 78498.48729591702 1.1508933668407977 1.3301301314286598 1.134268051967862 0.8551915587022416 0.8627504430529686 1.0713874541431387 1.4305340345172999 1.2131769367649061 1.244032652437093 1.0 16.26037723238548 -7.051682385529299 24.95756618610137 1.2413093673656554 1.062671314982188 0.17522836911063688 0.16195514235322644 591.7952026389108 285777.5567993755 0.0676693903581733 0.05241712675258882 8.878050570049403e-08 7.051682385529299 -0.17863805238346742 GEQVSQNGLPAEQGS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 GEQVSQNGLPAEQGSPR 17 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 GEQVSQNGLPAEQGS(1)PR;GEQVSQNGLPAEQGS(1)PR;GEQVSQNGLPAEQGS(1)PR;GEQVSQNGLPAEQGS(1)PR;GEQVSQNGLPAEQGS(1)PR;GEQVSQNGLPAEQGS(1)PR;GEQVSQNGLPAEQGS(1)PR 242.59 1.0805e-53 146709500.0 159195.2 210491.4 201521.6 163168.3 184698.0 132377.3 168768.8 124525.3 121234.2 119128.9 True False 186143.80311147778 231387.5951027997 206326.63921892413 154026.50914976568 148507.75276568672 125435.20135108192 152781.79748369902 121256.6428204617 123007.02082242726 140726.0265461461 1.3227389963322707 1.6442416572241123 1.4661583523874073 1.0945133102245175 1.055296993815063 0.8913433032229464 1.0856683815598223 0.8616504409061808 0.8740886376273225 1.0 17.10252964662643 -5.858376131713497 2.482349266643559 0.9587374405814421 1.5077561540757887 0.8392992015479446 0.10099805070633659 0.1011222463565814 1.2663075486275883 0.03019535931278475 0.05114319645643136 1.385555313877179e-06 5.858376131713497 0.5490187134943466 GEQVSQNGLPAEQGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 GEQVSQNGLPAEQGSPR 17 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 GEQVSQNGLPAEQGS(1)PR;GEQVSQNGLPAEQGS(1)PR;GEQVSQNGLPAEQGS(1)PR 284.84 8.720099999999998e-97 166383000.0 46439.0 62301.0 59474.0 53928.0 69946.0 58333.0 62850.0 65054.0 66548.0 51522.0 True False 45776.77134413041 62156.74586226205 54584.27729627909 57894.04501853434 65831.91379912695 55838.23357086457 66104.06547258829 68076.64633130297 59052.66345849302 60427.509051250345 0.7575485414317804 1.0286167151047891 0.9033017933932137 0.9580743262051842 1.0894361662879894 0.9240532076790808 1.0939399374633083 1.1265836934228939 0.977248018090713 1.0 15.882917851895213 -3.5652517129401207 0.5932023601281284 1.0389670604971892 4.1146429634371786e-18 0.47221231410499753 0.07544618313681511 12.614779406818101 1.110103916949855 0.03508072159719485 12.402977652587307 0.0002721123713587946 3.5652517129401207 -1.0389670604971892 GES(ph)ENAGTNQETR ddPTM_PC-9_AZD4547_30min_R2 2 GESENAGTNQETR 13 0 Q08170 Q08170 SRSF4 Serine/arginine-rich splicing factor 4 1 GES(1)ENAGTNQETR;GES(1)ENAGTNQETR 143.93 1.329e-05 859560.0 2130.3999999999996 2725.07 2251.08 5300.8 3188.44 3471.2000000000003 3446.1 5997.2 1983.7199999999998 4250.1 True False 2807.8228849272123 3605.895585851702 2221.2292083704565 4078.7824565436135 2745.7801424805757 3254.14531526237 3752.796224019714 5070.470541946114 2088.5753893553533 4101.305292629761 0.6846168925714947 0.8792068204070704 0.5415907985104425 0.9945083736812711 0.6694893324364006 0.793441376117555 0.9150248411801153 1.2363065366184733 0.5092465057669863 1.0 12.001867423540505 -7.237915300316002 4.535377568832016 0.9361166650287663 0.7607799069493165 0.12184273373377963 0.20194708232928069 0.4004296013605184 21.19461868398313 0.07757571720874708 0.05656469289514188 5.782088034494199e-08 7.237915300316002 -0.17533675807944982 GES(ph)ENAGTNQETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GESENAGTNQETR 13 0 Q08170 Q08170 SRSF4 Serine/arginine-rich splicing factor 4 1 GES(1)ENAGTNQETR;GES(0.999)ENAGTNQETR;GES(0.997)ENAGT(0.003)NQETR 181.71 7.916e-05 11634700.0 8260.7 13565.0 14607.7 12654.599999999999 17233.7 12080.8 15503.199999999999 9166.0 9008.74 10902.5 True False 9659.073353737938 14911.64355203814 14956.002968010745 11945.603788766743 13856.880198150577 11447.26158096705 14034.624662551887 8925.402212179772 9140.475779638344 12879.03694585748 0.7499841326912849 1.157822872527316 1.1612671840980562 0.9275230623986233 1.07592518418915 0.8888290039923398 1.0897262521687305 0.6930178280954937 0.7097173350821361 1.0 13.652737096807765 -7.760372679944772 24.999966179330556 0.7760256673666752 1.0140230991785693 0.29733655086485045 0.1436127099186181 30.081562979944156 705075.0326077002 0.06947700183927254 0.03717245289098542 1.7363102141018493e-08 7.760372679944772 0.23799743181189403 GES(ph)ENAGTNQETR ddPTM_PC-9_Lapatinib_30min_R1 3 GESENAGTNQETR 13 0 Q08170 Q08170 SRSF4 Serine/arginine-rich splicing factor 4 1 GES(0.999)ENAGTNQETR;GES(0.968)ENAGT(0.002)NQET(0.03)R;GES(0.99)ENAGTNQET(0.01)R 144.4 9.163799999999999e-05 3964200.0 4519.799999999999 5683.63 5933.65 2303.0899999999997 6084.62 7910.3 5200.1 5305.0 4308.5 4928.3 True False 4455.346823170192 5670.469903936184 5445.808201551374 2472.466921483018 5726.7346144231815 7571.994908809933 5469.335733715287 5551.48966685465 3823.231359483635 5780.150088453033 0.770801234395385 0.9810246822593834 0.9421568848930806 0.427751335803935 0.9907588084716763 1.309999704667956 0.9462272864923251 0.9604404006644781 0.6614415371533826 1.0 12.496891239162368 GES(ph)LDNLDSPR ddPTM_PC-9_Lapatinib_30min_R1 1 GESLDNLDSPR 11 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 GES(1)LDNLDSPR 179.46 0.0019294 11193000.0 29002.0 37609.0 33472.0 20289.0 32297.0 29041.0 36149.0 28083.0 34662.0 26897.0 True False 28588.42616168458 37521.918671190055 30720.061365656482 21781.120742119918 30397.353958345087 27798.98412787747 38020.61834158458 29387.83870203187 30758.000552958518 31546.110612000306 0.9062425004878222 1.189430897922374 0.9738145454283169 0.6904534448007124 0.9635848403695692 0.8812174809690355 1.2052394924121435 0.9315835813639917 0.9750172035869935 1.0 14.945174522739094 GES(ph)TSVFRK ddPTM_PC-9_AZD4547_30min_R2 1 GESTSVFRK 9 1 A2PYH4;C9JQ07 A2PYH4 HFM1 Probable ATP-dependent DNA helicase HFM1 1 GES(0.993)T(0.007)SVFRK 85.958 0.017677000000000002 36452000.0 28569.0 37057.0 37514.0 36712.0 38024.0 44578.0 39972.0 40799.0 41569.0 40923.0 True False 37653.347727884684 49034.95056086867 37016.53984878785 28248.61559474592 32745.023942016 41790.530612977054 43529.43056397547 34494.45201775152 43766.25247520454 39490.29822599179 0.9534834989699302 1.2416961320538917 0.937357819810645 0.7153305207544165 0.8291916094081008 1.058248037880638 1.1022816367419883 0.8734918085538261 1.1082786011071042 1.0 15.269210642448618 -9.208306135000605 15.93086596501431 0.9999999979675523 0.9769316635601346 0.001322388935863894 0.1458613043074098 0.0 0.0 0.1503931580173872 0.036475698580935 6.190045837527903e-10 9.208306135000605 -0.023068334407417734 GESDEPAPQVQPES(ph)PETVSPK ddPTM_PC-9_AZD4547_30min_R2 1 GESDEPAPQVQPESPETVSPK 21 0 A0A1B0GTL5 A0A1B0GTL5 1 GESDEPAPQVQPES(0.991)PET(0.008)VSPK 120.42 1.1242e-06 4419800.0 27094.0 26132.0 37450.0 37836.0 39090.0 38211.0 27783.0 34307.0 32263.0 35032.0 True False 35709.32840979061 34578.65796088783 36953.38853060469 29113.494760372807 33663.02824251537 35821.660129491334 30255.633177197316 29005.641446432535 33968.356313780096 33805.54034291093 1.0563158596954332 1.0228695536333596 1.093116339977505 0.8612048340318261 0.9957843566779301 1.0596387386839445 0.8949903734800668 0.8580144305403792 1.004816251100193 1.0 15.044972086714417 -5.742510903217187 24.9998534187287 0.9513239312402824 1.0539774902284047 0.35306318409149995 0.06437876450829598 287.80820563152815 380120.7186336408 0.018055136536896763 0.031208131802641065 1.8092104883953023e-06 5.742510903217187 0.10265355898812234 GESDEPAPQVQPES(ph)PETVSPK ddPTM_PC-9_Lapatinib_30min_R1 1 GESDEPAPQVQPESPETVSPK 21 0 A0A1B0GTL5 A0A1B0GTL5 1 GESDEPAPQVQPES(0.998)PET(0.002)VSPK 109.03 2.7841e-05 3343400.0 25688.0 17101.0 21735.0 18867.0 21661.0 19303.0 18295.0 16300.0 23227.0 15359.0 True False 25321.684409397752 17061.403685182308 19948.032199526268 20254.542118466965 20386.94256716451 18477.455687490758 19242.225581877494 17057.35750607555 20610.930668846784 18013.782685418926 1.4056839061289517 0.9471305379404009 1.1073760879591936 1.1243913880931737 1.1317413406827936 1.025739902061056 1.068194610644044 0.9469059222015849 1.1441756031358197 1.0 14.136813541830518 -4.749785184799007 24.97398302778638 1.0591036106706433 1.4056846848399804 0.6931097456474253 0.06994395175438785 298.24405165655253 639072.150393302 0.017083889779142613 0.2704033360129554 1.7791592184526387e-05 4.749785184799007 0.34658107416933714 GESENAGTNQETR ddPTM_PC-9_Lapatinib_30min_R1 2 GESENAGTNQETR 13 0 Q08170 Q08170 SRSF4 Serine/arginine-rich splicing factor 4 0 ; 127.52 0.00053501 1113700.0 8309.8 5206.4 10664.7 7597.599999999999 7232.299999999999 9179.0 7171.2 5567.6 10410.6 6427.6 False True 8191.30072816931 5194.344900680264 9787.889532932497 8156.352848850622 6806.9103332488785 8786.435567294084 7542.489647048911 5826.2910215230795 9238.048599521959 7538.602095761362 1.0865808573150364 0.6890329048671803 1.2983693009126738 1.081945000577308 0.9029406575359796 1.1655258436089002 1.0005156859638122 0.772860929322554 1.2254325778404094 1.0 12.88008130994821 -5.248927474789997 24.998668287470206 1.0452342267282322 0.8878069423241906 0.13260967461630735 0.17025550143066534 1627.4708227970366 3251657.528522251 0.041920884474296816 0.10920406237749382 5.637317886194006e-06 5.248927474789997 -0.15742728440404163 GESPVDYDGGR ddPTM_PC-9_AZD4547_30min_R2 1 GESPVDYDGGR 11 0 Q15084-3;Q15084;Q15084-4;Q15084-5;Q15084-2 Q15084-3 PDIA6 Protein disulfide-isomerase A6 0 128.35 0.0014487999999999999 9775500.0 35471.0 34202.0 41211.0 51083.0 43960.0 40139.0 39636.0 37926.0 40133.0 40205.0 False True 46750.0401573663 45257.12764343662 40664.51521321097 39306.603574482586 37856.91280483439 37629.10198470737 43163.52721489374 32065.408152779357 42254.34844685663 38797.435187449584 1.204977595335716 1.1664979250503822 1.0481238003682616 1.0131237640986566 0.9757581299363975 0.9698863289004178 1.1125355840237738 0.8264826785032444 1.0891015924816934 1.0 15.243673661738862 -5.286630334944618 1.692981172478917 0.9919779048717914 1.2152607910652962 0.5144147513521952 0.07238697190147854 0.34016738868393087 1.678726943638708 0.01994897194263803 0.08852380931182963 5.168561223954828e-06 5.286630334944618 0.22328288619350478 GESPVDYDGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GESPVDYDGGR 11 0 Q15084-3;Q15084;Q15084-4;Q15084-5;Q15084-2 Q15084-3 PDIA6 Protein disulfide-isomerase A6 0 ; 104.42 0.012369 15868400.0 77671.0 83730.0 91039.0 110600.0 97440.0 87119.0 100149.0 89658.0 91929.0 73919.0 False True 90819.1662278234 92042.16104770768 93209.71502733034 104403.44057003793 78347.33147889277 82550.32627576552 90662.16170402961 87304.57250050352 93273.28771241842 87319.92955751781 1.0400737459138767 1.0540796529969636 1.0674506438525344 1.1956427484434373 0.8972445566081821 0.9453778386455232 1.0382757082311922 0.9998241288432994 1.0681786871000523 1.0 16.414023346031833 -6.267484609708161 24.99894093370918 0.9915090270790288 1.0852336188853016 0.3973393480826989 0.05893800053025239 568.34975143104 2350302.1499578897 0.01900880565784912 0.022114897642147253 5.401512560121481e-07 6.267484609708161 0.0937245918062728 GESPVDYDGGR ddPTM_PC-9_Lapatinib_30min_R1 2 GESPVDYDGGR 11 0 Q15084-3;Q15084;Q15084-4;Q15084-5;Q15084-2 Q15084-3 PDIA6 Protein disulfide-isomerase A6 0 ; 133.75 0.00025261 24058000.0 86852.0 93981.0 94740.0 84049.0 79013.0 86836.0 89355.0 90139.0 87634.0 81830.0 False True 85613.47455329368 93763.3927686756 86950.84290697577 90230.24383924456 74365.6106855349 83122.22670460274 93981.36468262723 94327.18700859792 77763.73609306916 95974.20646837873 0.8920467040433548 0.9769645013899486 0.9059813683963519 0.9401509755537633 0.7748499666942976 0.8660892312976777 0.9792356523790786 0.9828389364144056 0.8102566195083937 1.0 16.550359106214614 -7.25420231030834 24.87220806228358 0.9416527136132753 0.8939179581937468 0.112600296054443 0.06921921405806676 1385.5228197847985 4761748.1203332525 0.02780952020298576 0.0210570039278076 5.5692625180761533e-08 7.25420231030834 -0.04773475541952854 GESS(ph)SPSPSAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GESSSPSPSAEK 12 0 E9PHV5;P28290-3;P28290;P28290-2 E9PHV5 SSFA2 Sperm-specific antigen 2 1 GES(0.001)S(0.499)S(0.499)PSPSAEK 105.17 0.0018229 3840000.0 25450.0 31167.0 32686.0 27702.0 29521.0 26044.0 30602.0 24438.0 25249.0 20437.0 True False 29758.182339587514 34261.05378447274 33465.35820234529 26149.94675109578 23736.571968271655 24678.206792158293 27703.15702070622 23796.528394201323 25618.218858584944 24142.06632079702 1.232627810070778 1.4191433876958073 1.3861845029195692 1.0831693693331081 0.9832038257563706 1.0222077292074796 1.1475056299071436 0.9856873093626606 1.061144415650797 1.0 14.559261541275694 -5.8144246014183 5.319130791758355 1.038243355841638 1.3537328111641653 0.8282436186801917 0.06391689528891231 0.07045341487719176 4.215998486974429 0.017895642084296393 0.02755512628800814 1.5331173502926436e-06 5.8144246014183 0.31548945532252737 GESS(ph)SPSPSAEK ddPTM_PC-9_Lapatinib_30min_R1 1 GESSSPSPSAEK 12 0 E9PHV5;P28290-3;P28290;P28290-2 E9PHV5 SSFA2 Sperm-specific antigen 2 1 GES(0.013)S(0.679)S(0.275)PS(0.031)PS(0.002)AEK 132.14 9.581100000000001e-05 5350200.0 26414.0 35470.0 33125.0 27007.0 33738.0 40484.0 39686.0 33438.0 39180.0 31421.0 True False 26037.33151626566 35387.87139427032 30401.590366197746 28993.18487271094 31753.597171460075 38752.59369281332 41740.74689491065 34991.65155142051 34767.135816309354 36852.077984149226 0.7065363187244098 0.960268004683245 0.8249627166010569 0.7867449125984552 0.8616501133292374 1.0515714665935947 1.1326565333131047 0.9495163764298741 0.9434240270321623 1.0 15.169458350644668 -6.6874327839304835 5.350025859490302 1.0193914946805835 0.8300527291352187 0.5980277395196901 0.07705425940567578 0.15158900311084175 7.734650145320895 0.02647053425213005 0.02618220355290108 2.0538428765996817e-07 6.6874327839304835 -0.18933876554536488 GESSS(ph)PSPSAEK ddPTM_PC-9_AZD4547_30min_R2 1 GESSSPSPSAEK 12 0 E9PHV5;P28290-3;P28290;P28290-2 E9PHV5 SSFA2 Sperm-specific antigen 2 1 GES(0.013)S(0.069)S(0.815)PS(0.069)PS(0.034)AEK 130.1 0.00015593 4204400.0 34351.0 36256.0 43085.0 40612.0 42131.0 44867.0 39330.0 51262.0 44591.0 41824.0 True False 45273.903454813495 47975.04297527739 42513.664748761075 31249.53084914527 36281.837883996304 42061.45939729103 42830.29380769428 43340.635783572616 46947.98922566926 40359.754490234816 1.1217586436450617 1.188685203396991 1.0533677740544087 0.7742745525547289 0.8989608173353686 1.0421634107677227 1.0612129421663659 1.0738577657616584 1.1632377307207975 1.0 15.300629778057198 -10.071842118257013 15.426576468366468 1.0000020962487544 1.0360317349190162 0.009206093806594762 0.11685112158908476 0.0 0.0 0.12677494356627841 0.030747440176793178 8.47535467922042e-11 10.071842118257013 0.036029638670261876 GESSS(ph)PSPSAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GESSSPSPSAEK 12 0 E9PHV5;P28290-3;P28290;P28290-2 E9PHV5 SSFA2 Sperm-specific antigen 2 1 GES(0.001)S(0.288)S(0.682)PS(0.03)PSAEK 134.18 5.6618999999999994e-05 3234500.0 22513.0 30392.0 27917.0 29748.0 30591.0 27719.0 30479.0 23862.0 23292.0 22422.0 True False 26324.006247981666 33409.11690626933 28582.647155812065 28081.316004317276 24596.913149330947 26265.366843489326 27591.808471149117 23235.647783878867 23632.60143586521 26486.931107545664 0.9938488585596243 1.2613434440787916 1.079122645041704 1.060195153991147 0.9286433769718122 0.9916349590235005 1.0417140573635084 0.877249526928374 0.8922363009859113 1.0 14.692993075940699 -5.985107180472544 2.1808912603565 0.9547563938600936 1.1302233164764113 0.45602097190901403 0.07743118581708655 0.2652298613738546 2.5379141557985045 0.024267673409211862 0.038294176207264906 1.0348867332306234e-06 5.985107180472544 0.1754669226163177 GESSS(ph)PSPSAEK ddPTM_PC-9_Lapatinib_30min_R1 1 GESSSPSPSAEK 12 0 E9PHV5;P28290-3;P28290;P28290-2 E9PHV5 SSFA2 Sperm-specific antigen 2 1 GESS(0.068)S(0.859)PS(0.068)PS(0.004)AEK 149.23 0.00015902 4199600.0 16894.0 27906.0 26659.0 21812.0 28332.0 28939.0 28166.0 26980.0 25214.0 25020.0 True False 16653.088462019838 27841.385371539545 24467.199926715948 23416.127242698967 26665.567462855153 27701.346430103866 29624.297662703546 28233.589295332415 22374.133804809193 29344.67366294561 0.5674995283061602 0.9487713406298904 0.8337867446660825 0.7979685687309995 0.9087021300402655 0.9439991307547978 1.0095289524419222 0.9621367618404905 0.7624597929354954 1.0 14.840811043791176 -4.756900893335691 24.99900645559623 0.9049432148179749 0.5674990234843474 0.6207813198232229 0.07969556938199432 96.06411261067773 529077.6004490422 0.020502592911176818 0.15956139870226754 1.7502460518784324e-05 4.756900893335691 -0.33744419133362746 GEVIS(ph)SGSKPLSPGPCLDIPSILSNK ddPTM_PC-9_AZD4547_30min_R2 1 GEVISSGSKPLSPGPCLDIPSILSNK 26 1 Q8TEP8;H0Y966;C9JT09;K7EPA2;A0A0A0MR42;K7ENP4;Q8TEP8-2;Q8TEP8-1 Q8TEP8 CEP192 Centrosomal protein of 192 kDa 1 GEVIS(0.423)S(0.423)GS(0.149)KPLS(0.006)PGPCLDIPSILSNK 62.871 0.00054308 8558600.0 13622.0 14349.0 18584.0 24557.0 28022.0 25405.0 15504.0 25387.0 27283.0 18365.0 True False 17953.51264479839 18987.033640011472 18337.56401743011 18895.763051867918 24131.62899492878 23816.421333901955 16883.82596477223 21464.022485224086 28725.123680651584 17722.046939870943 1.0130608899588622 1.071379265862036 1.0347317146629593 1.066229150389866 1.3616727840076759 1.3438865958717179 0.9527017969231935 1.2111480439053839 1.6208694051038761 1.0 14.113257627880785 -6.14866001015102 6.847703582447806 1.2485501380190287 1.0445813454285318 0.23885613080448653 0.17696309931055396 0.39494261198617164 21.318384823918418 0.052991160815163 0.06871493745882995 7.101334823565632e-07 6.14866001015102 -0.20396879259049694 GEVISSGSKPLS(ph)PGPCLDIPSILSNK ddPTM_PC-9_AZD4547_30min_R2 2 GEVISSGSKPLSPGPCLDIPSILSNK 26 1 Q8TEP8;H0Y966;C9JT09;K7EPA2;A0A0A0MR42;K7ENP4;Q8TEP8-2;Q8TEP8-1 Q8TEP8 CEP192 Centrosomal protein of 192 kDa 1 GEVIS(0.001)S(0.002)GS(0.001)KPLS(0.997)PGPCLDIPSILSNK;GEVIS(0.003)S(0.003)GS(0.003)KPLS(0.992)PGPCLDIPSILSNK 85.01299999999999 6.369399999999999e-07 31719000.0 86233.0 85299.0 104320.0 104953.0 113804.0 118702.0 85394.0 122124.0 107634.0 111366.0 True False 113653.3002421741 112870.23363714127 102936.64863852294 80757.70735768604 98004.27900003135 111279.54517523442 92993.9005699019 103252.54193033889 113323.31350083383 107467.11023717198 1.057563565181474 1.0502769953341538 0.9578432732707649 0.7514643985444454 0.9119467228972953 1.0354753647850834 0.8653242872602719 0.9607827148461344 1.0544929816270079 1.0 16.71353567231771 -10.130047446293027 14.333491492375375 1.000000685224177 0.9549595490640601 0.012607405679850303 0.09345575704569592 0.0 0.0 0.0962512302212708 0.0233443522822319 7.412292582279341e-11 10.130047446293027 -0.045041136160116846 GEVISSGSKPLS(ph)PGPCLDIPSILSNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GEVISSGSKPLSPGPCLDIPSILSNK 26 1 Q8TEP8;H0Y966;C9JT09;K7EPA2;A0A0A0MR42;K7ENP4;Q8TEP8-2;Q8TEP8-1 Q8TEP8 CEP192 Centrosomal protein of 192 kDa 1 GEVISSGS(0.002)KPLS(0.998)PGPCLDIPSILSNK;GEVISS(0.001)GS(0.001)KPLS(0.998)PGPCLDIPSILSNK 96.79299999999999 1.877e-09 35047000.0 103464.0 93801.0 104294.0 117463.0 142546.0 125225.0 154556.0 140200.0 132512.0 116040.0 True False 120978.41169285215 103112.9433707872 106780.76449719773 110881.92893018393 114615.13457502316 118657.98055398643 139915.33679146075 136519.8985541792 134449.73731192533 137077.13342786572 0.8825572046012677 0.7522257052818255 0.7789830573994977 0.8089017194726609 0.8361360622947169 0.8656292817534588 1.0207051555034785 0.9959348808969678 0.9808327176806407 1.0 17.06462840192416 -7.070945589837357 2.4194525535621754 1.0003854523319051 0.8054573171431889 0.8677295095397999 0.03451086254683955 0.1003901119514856 1.1596359388863782 0.01502990367001709 0.011377374474725132 8.492868704526064e-08 7.070945589837357 -0.1949281351887162 GEVISSGSKPLS(ph)PGPCLDIPSILSNK ddPTM_PC-9_Lapatinib_30min_R1 1 GEVISSGSKPLSPGPCLDIPSILSNK 26 1 Q8TEP8;H0Y966;C9JT09;K7EPA2;A0A0A0MR42;K7ENP4;Q8TEP8-2;Q8TEP8-1 Q8TEP8 CEP192 Centrosomal protein of 192 kDa 1 GEVISS(0.001)GS(0.001)KPLS(0.997)PGPCLDIPS(0.001)ILSNK 79.935 1.7556e-05 9955100.0 6790.2 8206.0 9024.1 7889.8 10529.0 10780.0 11136.0 9536.5 10231.0 10615.0 True False 6693.370502829827 8186.999511175139 8282.173332033355 8470.04221160125 9909.70492081045 10318.964529407362 11712.567591133527 9979.600604704876 9078.677042793792 12449.788606401578 0.5376292493342538 0.6576014878650591 0.6652461012691195 0.6803362273352999 0.7959737497643102 0.8288465656438082 0.9407844551762928 0.8015879562463774 0.7292233892329394 1.0 13.603833625530733 -5.973486197168565 0.8279835151389977 0.8620129040698994 0.5705368273344205 0.6883575011854595 0.07366227635181535 0.4622363907349888 0.6282206186331364 0.03625990030803067 0.08972388350907802 1.0629523656970422e-06 5.973486197168565 -0.29147607673547893 GEVLGLSSS(ph)LGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GEVLGLSSSLGK 12 0 F1LLU8;Q9NQG7-2;Q9NQG7-3;Q9NQG7;Q9NQG7-4 F1LLU8 HPS4 Hermansky-Pudlak syndrome 4 protein 1 GEVLGLS(0.001)S(0.205)S(0.794)LGK;GEVLGLS(0.048)S(0.031)S(0.921)LGK 152.38 0.00010819 6189200.0 30923.0 35958.0 35368.0 51896.0 59136.0 70483.0 86151.0 76757.0 80034.0 65977.0 True False 36157.6531429102 39527.672601856786 36211.307253886924 48988.43536910208 47548.725311327995 66786.7474017698 77990.1536007734 74742.21008076417 81204.34584054783 77938.10782635548 0.4639277774547558 0.5071674653678229 0.4646161969259631 0.6285556159285688 0.6100831369586953 0.8569203084910569 1.0006677833972295 0.9589944144819155 1.041908099969138 1.0 16.250041285874588 -6.748296428016363 1.1701767028571195 1.0174797498306487 0.48766889230955607 0.9659162314658092 0.042185160690322195 0.0739733912559595 0.21443587275696016 0.020909403844150954 0.019097857881524422 1.7852686224965353e-07 6.748296428016363 -0.5298108575210927 down GEVPGGS(ph)AHYGGPSPEKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GEVPGGSAHYGGPSPEKK 18 1 J3KS37;O94762-4;O94762 J3KS37 RECQL5 ATP-dependent DNA helicase Q5 1 GEVPGGS(0.398)AHY(0.312)GGPS(0.291)PEKK 85.469 0.0079407 0.0 8545.8 7482.5 12600.0 20407.0 18060.0 18105.0 15192.0 17364.0 16143.0 10521.0 True False 9992.43515275626 8225.313149880236 12900.431785766099 19263.661950386653 14521.272644794772 17155.541927969054 13752.903779444783 16908.213398678774 16379.06083544444 12428.374015809832 0.8040018058713977 0.6618173173270305 1.037982262953768 1.5499744315613464 1.168396817340918 1.3803528849506708 1.1065730530759734 1.3604525722488112 1.3178764023844982 1.0 13.601349942812767 -5.486459717745718 4.734153475979551 1.2799516240044266 0.7477342094496221 0.6694281401111342 0.1498807499510565 0.10366842432944126 5.530711221934516 0.03766393843416042 0.0774413394896303 3.2624230904765835e-06 5.486459717745718 -0.5322174145548045 GEVPGGSAHYGGPS(ph)PEKK ddPTM_PC-9_Lapatinib_30min_R1 2 GEVPGGSAHYGGPSPEKK 18 1 J3KS37;O94762-4;O94762 J3KS37 RECQL5 ATP-dependent DNA helicase Q5 1 GEVPGGSAHYGGPS(1)PEKK;GEVPGGSAHY(0.046)GGPS(0.954)PEKK 87.49600000000001 0.00075019 12450100.0 101703.0 47398.7 96273.0 54047.2 93497.9 79557.7 72752.8 65163.1 94950.6 69102.4 True False 100252.696569954 47288.95122231745 88357.80556452689 58022.01138417383 87998.53734594397 76155.20262905677 76519.58400181556 68190.81551559214 84256.26355385555 81046.65776683978 1.2369750873424958 0.5834781164987869 1.090209121500362 0.7159087491441691 1.0857762648165432 0.9396464299384799 0.9441423756418432 0.8413772682862241 1.039601951214933 1.0 16.306465072107486 -8.287921427723706 24.229888818278148 1.0198010286717767 0.92239003416787 0.037849130887449234 0.17872774090002913 2009.8318852771358 1838879.6207078488 0.1549940439489111 0.04007584744652718 5.153218678470184e-09 8.287921427723706 -0.09741099450390667 GEVPPKET(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 GEVPPKETPK 10 1 P49006 P49006 MARCKSL1 MARCKS-related protein 1 GEVPPKET(1)PK;GEVPPKET(1)PK 105.66 0.0017504999999999999 295740000.0 790870.0 747830.0 635930.0 656450.0 863440.0 800770.0 901700.0 763750.0 804470.0 881960.0 True False 1042350.2088820784 989551.422887293 627497.1526907202 505115.5945513982 743566.2600592865 750697.7253118934 981949.5531756412 645729.9867290292 846992.6418419448 851082.8488477317 1.224734125817834 1.1626969386435548 0.7372926778400941 0.5934975604728336 0.8736708313015469 0.8820501157181722 1.1537649413392457 0.7587157790845783 0.9951941141672346 1.0 19.698940052651167 -5.166358670332113 6.011512562892174 0.8663528378779354 1.2052955855738345 0.425056051036814 0.14873146806535498 0.22138502006979047 11.39532353906698 0.040041152784147396 0.10974796610950363 6.8177540442771694e-06 5.166358670332113 0.33894274769589916 GEVPPKET(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GEVPPKETPK 10 1 P49006 P49006 MARCKSL1 MARCKS-related protein 1 GEVPPKET(1)PK 107.39 0.022454 14495000.0 33577.0 35031.0 28176.0 40811.0 44090.0 39282.0 45729.0 34451.0 31761.0 39928.0 True False 39260.92292402081 38508.646168186395 28847.822698075044 38524.49198104717 35450.88100271324 37221.9827679912 41397.218070710274 33546.69775385177 32225.44453909133 47166.630330125925 0.8323876997196545 0.8164383569201134 0.6116150866866055 0.8167743108084846 0.7516093635391696 0.7891592532150223 0.8776802112206296 0.7112379561366516 0.683225498907615 1.0 15.52547891534029 -6.903371867964024 6.28093185387198 0.79931246111402 0.7631063623266681 0.04364035118220988 0.10063275596675236 1.0413155583241624 56.99013979610196 0.03558744539764161 0.03135778341346341 1.24918894458284e-07 6.903371867964024 -0.036206098787351926 GEVPPKET(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 GEVPPKETPK 10 1 P49006 P49006 MARCKSL1 MARCKS-related protein 1 GEVPPKET(1)PK;GEVPPKET(1)PK 125.82 0.00082697 180900000.0 1938285.0 1761786.0 1359474.0 1568604.0 1474590.0 1320136.0 1276351.0 1220109.0 1256164.0 1260699.0 True False 1910644.7004620677 1757706.6927608093 1247703.2954413963 1683964.3708695462 1387857.515355484 1263676.8606673197 1342434.2095465935 1276799.718366892 1114681.5823266583 1478609.1423741777 1.2921905091119468 1.1887568136759181 0.8438357776132644 1.1388840516470993 0.9386236535282236 0.854638879506896 0.9079033607157803 0.8635140158248693 0.7538716963002359 1.0 20.495809308115838 -1.522878745282188 0.45233322966615186 0.8669567956451482 11.235840891776487 0.6274690435959145 0.10075890987086432 55.11847255426901 0.6604822148996773 0.061513580935683904 528.6269839570075 0.02999999999987218 1.522878745282188 10.368884096131339 GEVPSAMIVS(ph)FLRPS(ph)QPFRT(ph)HVS(ph)EK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GEVPSAMIVSFLRPSQPFRTHVSEK 25 2 H0Y944 H0Y944 CAST 4 GEVPS(0.008)AMIVS(0.993)FLRPS(0.999)QPFRT(1)HVS(1)EK 53.778999999999996 0.028291000000000004 0.0 1331.0 3771.1 4817.8 5875.3 5683.2 4656.9 3503.4 6296.5 5230.8 1338.1 True False 1556.312011551707 4145.469885668341 4932.674623608245 5546.125988979601 4569.617757192558 4412.683965996082 3171.532589580493 6131.22354669321 5307.290554298635 1580.6869376062289 0.9845795359760263 2.622574898952594 3.1205892237448496 3.5086808507309994 2.8909062563095045 2.7916242369147377 2.006426771884014 3.878834828595631 3.3575848753048625 1.0 10.626335948192606 -4.76715516800822 3.5798328469493246 2.9181571877475863 0.7283730072711119 0.32547403822616283 0.7768610357534312 0.31865466471461434 6.763227888578909 0.18727357834384653 1.9306764008377404 1.7094044570529707e-05 4.76715516800822 -2.189784180476474 GEVRPELGSR ddPTM_PC-9_Lapatinib_30min_R1 1 GEVRPELGSR 10 1 F8VPD4;P27708 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 0 81.525 0.020954 3218700.0 11622.0 10273.0 10755.0 10365.0 11574.0 9810.0 10721.0 10803.0 13469.0 8218.7 False True 11456.268148786232 10249.213499671234 9870.765415500578 11127.27667662639 10893.240075359501 9390.449168226924 11276.080921744124 11304.946818290446 11951.979385142178 9639.291344270629 1.1884969277949642 1.0632745845744282 1.0240135984029088 1.1543666727368072 1.1300872321733684 0.9741845985191006 1.1698039325729443 1.172798540321104 1.2399230356540845 1.0 13.234711371813725 GFAFVQYVNER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GFAFVQYVNER 11 0 B4DY08;B2R5W2;G3V4W0;G3V576;G3V555;G3V575;G3V5X6;G3V3K6;G3V251;B4DSU6;G3V4M8;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 0 102.06 0.016012000000000002 4376900.0 24616.0 27286.0 35709.0 32669.0 37336.0 32724.0 38179.0 31278.0 32174.0 29416.0 False True 28783.002611838347 29994.77375310822 36560.437987136655 30838.661844327038 30020.27881871858 31007.895832690385 34562.4087279767 30456.985641780382 32644.483882772067 34748.887943072106 0.8283143523612191 0.8631865803086307 1.0521326048486026 0.8874719068664569 0.8639205625198642 0.8923421055513933 0.9946335199157765 0.8764880675225348 0.9394396717458235 1.0 15.084679188042093 -14.522878745280186 0.10376756846073568 1.266166488852971 0.8591419149001288 0.18767445836883345 0.06263934470146537 362.42272498759684 2.5277377904094904 20.94045730448384 0.9870785329284161 3.0000000000010443e-15 14.522878745280186 -0.4070245739528421 GFAFVQYVNER ddPTM_PC-9_Lapatinib_30min_R1 1 GFAFVQYVNER 11 0 B4DY08;B2R5W2;G3V4W0;G3V576;G3V555;G3V575;G3V5X6;G3V3K6;G3V251;B4DSU6;G3V4M8;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 0 117.67 0.0052481 20765000.0 69110.0 50517.0 62616.0 62748.0 64119.0 65225.0 50896.0 56936.0 66594.0 50700.0 False True 68124.47872677825 50400.03099025521 57467.95418474978 67362.6972411918 60347.64648280419 62435.47879690125 53531.145843959406 59581.45441508693 59093.48245409148 59463.42744649647 1.1456534150856803 0.8475803221333609 0.9664420073406943 1.1328424904837997 1.014869964182662 1.049981164524681 0.9002364670641503 1.0019848665584685 0.9937786130350819 1.0 15.859715001516058 -9.491291883255453 10.29705154353495 0.9999969241590287 1.0021778003974713 0.0 0.08703149550766674 0.0 0.0 0.0830219681729167 0.020135784942564898 3.2263250248976145e-10 9.491291883255453 0.0021808762384425417 GFAFVTFDDHDSVDK ddPTM_PC-9_AZD4547_30min_R2 1 GFAFVTFDDHDSVDK 15 0 F8VZ49;Q32P51;F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;A0A2R8Y4L2;H0YH80 F8VZ49;F8W6I7 HNRNPA1;HNRNPA1L2 Heterogeneous nuclear ribonucleoprotein A1-like 2;Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 0 191.19 8.957000000000001e-08 3493500.0 6093.1 5919.7 19986.0 39415.0 32086.0 26582.0 14693.0 40458.0 19346.0 29554.0 False True 8030.579055646823 7833.127258957127 19720.972581379574 30328.480705679605 27631.41274467508 24919.823337838287 16000.648535887414 34206.145732351084 20368.590064358214 28519.323455537495 0.28158378539963413 0.2746603463847666 0.6914951054896228 1.0634361910079193 0.9688663473294976 0.8737873244675337 0.5610458663520864 1.199402425716007 0.7142031295417465 1.0 14.799652137666525 -5.3899461051729265 3.2169985584911154 0.9055280755966465 0.2707844431117683 0.6863615301526287 0.168945690651414 0.13573340261940653 2.6042235307343886 0.044978590153270145 0.10778902253501019 4.074308357847433e-06 5.3899461051729265 -0.6347436324848782 GFAFVTFDDHDSVDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GFAFVTFDDHDSVDK 15 0 F8VZ49;Q32P51;F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;A0A2R8Y4L2;H0YH80 F8VZ49;F8W6I7 HNRNPA1;HNRNPA1L2 Heterogeneous nuclear ribonucleoprotein A1-like 2;Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 0 ; 132.51 5.4473e-06 4495500.0 13041.3 15855.1 42368.0 45619.0 54261.0 45985.0 49676.0 37193.0 41337.0 23857.0 False True 15248.934512583979 17429.08954529452 43378.21380153476 43063.11532879351 43628.94656584764 43573.46564803406 44970.32965690486 36216.72315924092 41941.47542307917 28182.08524809191 0.541086097013223 0.618445703781787 1.5392123549293328 1.5280315473358783 1.548109239673866 1.5461405806010837 1.595706253140002 1.2850973531737864 1.4882317988133562 1.0 14.782490742999007 -5.256691079110499 22.825643628233255 1.4676669019512312 0.5797654212053963 0.8012330018353657 0.17124396573469056 42.83480534950674 205904.56779241166 0.04136373160136156 0.10175784159685244 5.53743856376296e-06 5.256691079110499 -0.8879014807458349 GFAFVTFDDHDSVDK ddPTM_PC-9_Lapatinib_30min_R1 1 GFAFVTFDDHDSVDK 15 0 F8VZ49;Q32P51;F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;A0A2R8Y4L2;H0YH80 F8VZ49;F8W6I7 HNRNPA1;HNRNPA1L2 Heterogeneous nuclear ribonucleoprotein A1-like 2;Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 0 101.72 0.0013584 2999300.0 15765.0 12600.0 23831.0 16087.0 23724.0 34469.0 21909.0 20428.0 27551.0 22389.0 False True 15540.188209053078 12570.825474141693 21871.70717032026 17270.091644658827 22328.600963178567 32994.84122116348 23043.34081843969 21377.15945608044 24447.91625510818 26258.90881853273 0.5918063205309312 0.47872611771550805 0.8329252110767025 0.6576850456356407 0.8503247837708978 1.2565198900373473 0.8775437310699068 0.8140916899407906 0.931033213301445 1.0 14.680519346244846 -5.854901811434086 1.1758544570256866 0.9571361951829366 0.5489140321499829 0.5634417286175135 0.1376111237634722 0.4059838639843974 1.1210593163157228 0.053628900815814354 0.1264596200820839 1.3966840982178842e-06 5.854901811434086 -0.40822216303295367 GFAFVTFDDHDTVDK ddPTM_PC-9_AZD4547_30min_R2 2 GFAFVTFDDHDTVDK 15 0 P51991;P51991-2 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 0 ; 121.42 5.5486000000000004e-05 10101800.0 41104.0 42422.0 76902.0 102088.0 89499.0 75662.0 64490.0 100614.0 73639.0 74679.0 False True 54174.21698368763 56134.08189257551 75882.22923312579 78553.18884387726 77073.60871519291 70930.84317912583 70229.48506631595 85066.41817971147 77531.40720300199 72064.51094051848 0.7517461268612873 0.7789421056212839 1.052976399101056 1.0900398520530374 1.069508523811518 0.9842687094299667 0.974536344585518 1.1804203909733693 1.075861144287732 1.0 16.13700134088711 -5.25172161551927 5.378286322534223 1.0571710018742064 0.7606151778621795 0.804370487149157 0.056860978167750036 0.06913484234903018 7.079911843330406 0.015665068391091094 0.039241673061944884 5.601165233546377e-06 5.25172161551927 -0.29655582401202696 GFAFVTFDDHDTVDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GFAFVTFDDHDTVDK 15 0 P51991;P51991-2 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 0 112.17 0.00029041 3016000.0 16953.0 21066.0 27462.0 29537.0 31955.0 30709.0 27566.0 24480.0 23461.0 21980.0 False True 19822.80806298731 23157.29325965614 28116.79823021497 27882.13765024603 25693.647140886875 29098.565979895135 24954.748919442794 23837.425938704015 23804.072741148626 25964.800006415735 0.7634492874233278 0.8918725834180938 1.0828813710587983 1.0738437285616116 0.9895569052924783 1.120692860053036 0.9610992156025325 0.9180669958102485 0.9167824414309678 1.0 14.664269492675391 -4.968205743575829 3.549655487066317 1.008732496658298 0.7700755126111302 0.5839362454986663 0.0650997043061868 0.17899273721331377 4.572581532225405 0.018306440782425062 0.0890277645432588 1.075955367526298e-05 4.968205743575829 -0.23865698404716784 GFAFVTFESPADAK ddPTM_PC-9_Lapatinib_30min_R1 2 GFAFVTFESPADAK 14 0 P38159;H0Y6E7;H3BT71;Q96E39;H3BR27;P38159-3;A0A1B0GUK8;Q8N7X1;O75526 P38159;O75526 RBMX;RBMXL1;RBMXL3;RBMXL2 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1;RNA-binding motif protein, X-linked-like-3;RNA-binding motif protein, X-linked-like-2 0 ; 207.88 2.1388999999999998e-60 4314600.0 85913.0 80549.0 100294.0 85221.0 83959.0 77556.0 80460.0 68567.0 77466.0 77488.0 False True 84687.8648654855 80362.49373941589 92048.2144660356 91488.43662892231 79020.69668974496 74239.11067186619 84625.8251061965 71752.87313613991 68740.96332685597 90881.69755373019 0.9318473041881417 0.8842538806221656 1.0128355537330909 1.006676141528204 0.8694896642200935 0.8168763642203676 0.9311646611372421 0.7895195079704456 0.7563785137949872 1.0 16.471702162339618 -6.400637239875712 5.87842298102413 0.84950787565255 0.9569342192887542 0.2960118724266986 0.07363429912060562 0.2867201915633853 12.62393569487694 0.02315840681843337 0.026238139133581397 3.975234566310988e-07 6.400637239875712 0.10742634363620418 GFCFITFK ddPTM_PC-9_Lapatinib_30min_R1 1 GFCFITFK 8 0 Q14103-3;Q14103;H0YA96;H0Y8G5;Q14103-4;Q14103-2 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 0 107.59 0.009971899999999999 0.0 10688.0 8747.1 13401.0 7353.4 12755.0 12809.0 9923.5 8402.1 11428.0 8628.0 False True 10535.587160060846 8726.846627370223 12299.221509355952 7894.193566223298 12004.77597729484 12261.188929237376 10437.290273941593 8792.49223937407 10140.858297824987 10119.338303912651 1.0411339994421624 0.8623930108153396 1.215417563873761 0.7801096602503151 1.1863202530399821 1.2116591580396692 1.0314202332682174 0.8688801555309645 1.0021266206609591 1.0 13.304827335898446 -7.551251880651492 23.12245706284582 0.9513318094170424 1.0491008670221431 0.08207647722301614 0.138543186859421 240.4908558863028 195980.30997416968 0.06497936605003321 0.03751739689615663 2.8102704664542397e-08 7.551251880651492 0.09776905760510068 GFCFLEYEDHK ddPTM_PC-9_AZD4547_30min_R2 2 GFCFLEYEDHK 11 0 O43390-4;O43390;O43390-2;B4DT28;O43390-3;O60506-2;O60506;O60506-4;O60506-3;B7Z645;O60506-5 O43390-4;O60506-2 HNRNPR;SYNCRIP Heterogeneous nuclear ribonucleoprotein R;Heterogeneous nuclear ribonucleoprotein Q 0 ; 138.76 8.7737e-05 16619900.0 80137.0 68623.0 95288.0 120626.0 91107.0 96214.0 82195.0 92973.0 77558.0 93718.0 False True 105618.89904685116 90804.04275409476 94024.41885992675 92817.53935312213 78458.36567129298 90197.72337020462 89510.195767186 78606.15915699922 81657.55754220481 90436.961345539 1.1678731513690008 1.0040589754796516 1.0396680456863305 1.0263230649522541 0.8675475657737046 0.9973546438118336 0.9897523582773635 0.8691817812925293 0.9029223928722009 1.0 16.464624898337597 -1.522878745280339 0.4714973133219106 0.9327120350526885 6.639698998668437 0.5796990985837882 0.0553253867203943 69.57034376886497 0.7965670575207171 0.03311968063482996 387.25709761977896 0.029999999999999905 1.522878745280339 5.706986963615749 GFCFLEYEDHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GFCFLEYEDHK 11 0 O43390-4;O43390;O43390-2;B4DT28;O43390-3;O60506-2;O60506;O60506-4;O60506-3;B7Z645;O60506-5 O43390-4;O60506-2 HNRNPR;SYNCRIP Heterogeneous nuclear ribonucleoprotein R;Heterogeneous nuclear ribonucleoprotein Q 0 ; 127.83 0.00028578 15846200.0 92359.0 93670.0 77729.0 99351.0 102857.0 85585.0 102465.0 88370.0 93847.0 74571.0 False True 107993.55452659965 102968.938556536 79582.35414887397 93784.68557028777 82702.90921515274 81096.7719362183 92758.77341764166 86050.38113575468 95219.33483391919 88090.13199628862 1.2259438381946073 1.1689043508400492 0.9034196265278261 1.0646446252826487 0.938844196744275 0.9206113113740713 1.0529984609575762 0.9768447292073547 1.0809307771037389 1.0 16.426692794638527 -5.122389518260237 5.272248544861959 0.9921964862435967 1.2124204794631048 0.6716632089058887 0.05784957854567911 0.11578018730428866 4.399068373159056 0.014335679787797987 0.040599636096626084 7.544152898650156e-06 5.122389518260237 0.22022399321950814 GFCFLEYEDHK ddPTM_PC-9_Lapatinib_30min_R1 2 GFCFLEYEDHK 11 0 O43390-4;O43390;O43390-2;B4DT28;O43390-3;O60506-2;O60506;O60506-4;O60506-3;B7Z645;O60506-5 O43390-4;O60506-2 HNRNPR;SYNCRIP Heterogeneous nuclear ribonucleoprotein R;Heterogeneous nuclear ribonucleoprotein Q 0 ; 107.03 0.0019814 14470000.0 114741.0 97738.0 99662.0 96924.0 94856.0 101789.0 93754.0 91400.0 97042.0 96352.0 False True 113104.77229907784 97511.69366600503 91468.17506644537 104052.11428898563 89276.75657407133 97435.72175174834 98608.12337815479 95646.77767210468 86112.10806243723 113006.31481903039 1.0008712564444306 0.8628871211503656 0.8094076442800878 0.9207637153341022 0.7900156439668009 0.8622148408943608 0.8725894967557076 0.8463843620179503 0.7620114698929714 1.0 16.786043867462674 -4.764948265561662 5.185686009494704 0.8519074126493998 1.0090750894571852 0.30500122093207693 0.06400068202039681 0.1789289965104716 13.577391781951551 0.014683745043662254 0.10166821120450059 1.7181130416557847e-05 4.764948265561662 0.15716767680778532 GFCYVEFDEVDSLK ddPTM_PC-9_Lapatinib_30min_R1 2 GFCYVEFDEVDSLK 14 0 Q15056;Q15056-2 Q15056;Q15056-2 EIF4H Eukaryotic translation initiation factor 4H 0 ; 174.23 1.7211e-19 0.0 13623.6 14347.900000000001 16070.8 14458.7 15518.3 11025.8 12552.2 13224.8 12223.7 13988.4 False True 13429.32496573774 14314.678319082343 14749.520859081971 15522.041030809272 14605.544104151666 10554.252236395147 13202.0914976137 13839.27248750601 10846.938184732533 16406.276301628637 0.8185480189922574 0.8725123273500726 0.8990169730115906 0.9461038413249454 0.8902412610655464 0.6433057716666295 0.8046976202822538 0.8435352564513495 0.6611456484891557 1.0 14.001960210065784 -6.623712771079388 21.550206287949514 0.7799809139846162 0.8887941213665935 0.18767074610840484 0.09718725591993685 6.836298312073307 1444.6788996425116 0.03052536124900729 0.03052533031248281 2.378412775122071e-07 6.623712771079388 0.1088132073819773 GFDNPEENS(ph)SEFPVTFKEESK ddPTM_PC-9_Lapatinib_30min_R1 1 GFDNPEENSSEFPVTFKEESK 21 1 Q8IWI9-3;Q8IWI9;H3BU53 Q8IWI9-3 MGA MAX gene-associated protein 1 GFDNPEENS(0.968)S(0.032)EFPVTFKEESK 86.18 0.00031292 0.0 13115.0 10669.0 13141.0 11865.0 7423.7 7352.0 10024.0 9906.5 12157.0 9222.6 True False 12927.977695003556 10644.296586001401 12060.59770572693 12737.591680479714 6987.052561555758 7037.572098349071 10542.993672191307 10366.792155456278 10787.75064111467 10816.714121657958 1.1951852983817222 0.9840600820436466 1.1149964370028402 1.1775842032263426 0.6459496371052099 0.6506201438991502 0.9746946765544455 0.958404931373677 0.9973223402026226 1.0 13.40097468644535 -6.237152796902842 24.99891823068087 0.863234721495989 1.1081810570522113 0.4490371870896245 0.13357459942636737 813.870531814539 837741.6874455046 0.04279009961479995 0.055215904175749925 5.792248731198337e-07 6.237152796902842 0.24494633555622225 GFEAKS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 GFEAKSR 7 1 F5GXB6;F5H280;Q9NYS7;Q9NYS7-2 F5GXB6 WSB2 WD repeat and SOCS box-containing protein 2 1 GFEAKS(1)R 74.439 0.016127000000000002 1953600.0 8807.8 6177.6 8537.1 5786.4 8729.7 8719.6 7678.3 7148.2 8069.9 5984.6 True False 8682.199156847302 6163.296146750612 7835.2125921589895 6211.951158864538 8216.236209250548 8346.683034380376 8075.844803789558 7480.331467787072 7160.9828821856745 7019.030136021755 1.2369514004919484 0.8780837277105414 1.1162813722580525 0.8850155988054137 1.170565740569301 1.1891504770075125 1.1505642015047373 1.0657215203277035 1.0202239830023547 1.0 12.77705598262544 GFEGS(ph)CSQK ddPTM_PC-9_AZD4547_30min_R2 1 GFEGSCSQK 9 0 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 GFEGS(0.57)CS(0.43)QK 70.942 0.036316 4945800.0 17187.0 21703.0 16531.0 21462.0 24264.0 39135.0 22063.0 28800.0 22384.0 17877.0 True False 22652.108488191883 28718.0703247034 16311.788138836477 16514.267484594584 20895.362427126973 36687.88226342269 24026.564258305596 24349.621758161822 23567.17254215831 17251.13167133531 1.3130795660107852 1.6647064593693695 0.9455488746828326 0.9572860377638234 1.2112458953546195 2.126694234464845 1.3927529344772451 1.4114796769316558 1.3661232776582308 1.0 14.074403385096558 GFEGS(ph)CSQKESEEGNPVR ddPTM_PC-9_Lapatinib_30min_R1 1 GFEGSCSQKESEEGNPVR 18 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 GFEGS(0.498)CS(0.498)QKES(0.004)EEGNPVR 54.225 0.020285 13249000.0 19117.0 38990.0 25949.0 42179.0 43716.0 40784.0 43103.0 27884.0 33174.0 36110.0 True False 18844.38807437155 38899.72105053848 23815.573386036693 45280.98436501927 41144.71082896285 39039.76339214748 45334.662435401224 29179.59243554665 29437.59478229318 42351.56538644946 0.44495139441530257 0.9184954722590866 0.5623304160949992 1.0691690838777612 0.9715038972827968 0.92180213496048 1.070436523933215 0.6889849801132207 0.6950769000786887 1.0 15.370127674573995 -5.754298537229443 24.998910827685357 0.912652007552791 0.6695827325817574 0.3565072809391344 0.1678857786310848 210.83385344923673 738085.8970965754 0.04644274903801078 0.0783301139631884 1.7607652672810585e-06 5.754298537229443 -0.2430692749710336 GFEGSCS(ph)QK ddPTM_PC-9_Lapatinib_30min_R1 2 GFEGSCSQK 9 0 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 GFEGS(0.18)CS(0.82)QK;GFEGS(0.146)CS(0.854)QK 85.53299999999999 0.012362 14588500.0 52934.0 78179.0 54403.0 54383.0 82906.0 74069.0 81609.0 76008.0 67303.0 65733.0 True False 52179.15145309328 77997.98132880357 49930.195341653016 58382.50723636981 78029.63207946725 70901.24153327224 85834.31470409615 79539.60916084613 59722.627407990454 77094.86146628317 0.6768175006827586 1.0117143976309675 0.6476462165184588 0.7572814338852265 1.0121249405654993 0.919662350833594 1.1133597372327482 1.031710903269891 0.7746641769907022 1.0 16.23434708425315 -6.260213810585639 24.982743385709036 0.9809649694681161 0.7814099403267606 0.3932809835920211 0.12255997515761169 118.17745963008609 2408999.3558312766 0.036593168968481374 0.044629096561319026 5.492703920931491e-07 6.260213810585639 -0.19955502914135548 GFEGSCS(ph)QKESEEGNPVR ddPTM_PC-9_Lapatinib_30min_R1 1 GFEGSCSQKESEEGNPVR 18 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 GFEGS(0.194)CS(0.805)QKES(0.001)EEGNPVR 66.436 0.0065887 17672000.0 24224.0 37060.0 37521.0 31980.0 47315.0 48140.0 47973.0 47299.0 37803.0 44767.0 True False 23878.561317862474 36974.189846959605 34436.16821524845 34331.915882152636 44532.024724869094 46081.16441982104 50456.80720630823 49496.68421348879 33545.228056762186 52504.91630172206 0.45478715137156217 0.7042043383992009 0.6558655958493359 0.6538800230603665 0.8481496183893265 0.8776542782206028 0.9609920510368157 0.9427057064343018 0.6388968961305052 1.0 15.680164895509918 -6.23183354085891 2.0011089010808916 0.8873067960601649 0.6104315490746801 0.5839494122395295 0.1087295434554072 0.24941879353581972 1.961994810214651 0.03671322211446562 0.048841698782206705 5.863628663238193e-07 6.23183354085891 -0.2768752469854848 GFFDPNTHENLTYR ddPTM_PC-9_AZD4547_30min_R2 1 GFFDPNTHENLTYR 14 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 104.81 0.00086573 6034000.0 30820.0 38356.0 44284.0 47251.0 50318.0 43725.0 40925.0 45392.0 30914.0 43902.0 False True 40620.11890417606 50753.82690753918 43696.7652253484 36358.01197067278 43332.21425190302 40990.868837821785 44567.24571776985 38377.70940439171 32548.050927818145 42365.00434272882 0.9588130470981 1.198013022657701 1.0314354005925683 0.8582086213550211 1.0228303979706828 0.9675643723817325 1.0519825598794965 0.9058823432170506 0.768276822646058 1.0 15.370585396500262 -5.836216816450066 0.5110848956560813 0.9161416383611445 1.1038996448006944 0.17893567373442576 0.10058046007303609 2.8962885901609594 1.208324767075709 0.07799500919160968 0.29240180632121565 1.4580861460527255e-06 5.836216816450066 0.18775800643954987 GFFDPNTHENLTYR ddPTM_PC-9_Lapatinib_30min_R1 1 GFFDPNTHENLTYR 14 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 116.9 0.00067835 0.0 46746.0 44968.0 54997.0 43807.0 51821.0 44417.0 40241.0 47083.0 46893.0 39158.0 False True 46079.393467833506 44863.87935882566 50475.358954559306 47028.712915868084 48772.990664005956 42517.38845108411 42324.48207927482 49270.64806494204 41611.41653481866 45926.40812524476 1.0033310974847314 0.9768645359000969 1.0990486958376806 1.0240015458560847 1.0619813883767777 0.9257721251602347 0.9215717885851814 1.0728173631732159 0.9060455244255377 1.0 15.487036335271789 -6.754836942183795 24.999941196339762 0.9670630960559471 1.033088698408689 0.2829744143781958 0.05392691215559221 220.9250237749687 836525.4369576554 0.017938780016118806 0.017540243866794567 1.7585837582040498e-07 6.754836942183795 0.06602560235274202 GFGDGYNGYGGGPGGGNFGGS(ph)PGYGGGR ddPTM_PC-9_AZD4547_30min_R2 5 GFGDGYNGYGGGPGGGNFGGSPGYGGGR 28 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 GFGDGYNGYGGGPGGGNFGGS(1)PGYGGGR;GFGDGYNGYGGGPGGGNFGGS(0.999)PGYGGGR;GFGDGYNGYGGGPGGGNFGGS(0.997)PGY(0.003)GGGR;GFGDGYNGYGGGPGGGNFGGS(0.918)PGY(0.082)GGGR;GFGDGYNGYGGGPGGGNFGGS(0.999)PGY(0.001)GGGR 180.16 1.2654e-18 136559400.0 354437.0 320060.0 448557.0 622527.0 506846.0 478572.0 372172.0 536996.0 366768.0 436381.0 True False 467140.59325241536 423513.1358855718 442608.8410980623 479013.0180962733 436479.18169879704 448646.8171859143 405294.5870073027 454015.60714048235 386154.60770828824 421103.43401403807 1.1093250624900926 1.0057223515100886 1.0510691800326362 1.1375186697724833 1.036512995247259 1.0654076432227766 0.9624585179559272 1.078156981083529 0.9170065511634257 1.0 18.683815114880467 -7.241716903337709 23.281761161273117 0.9959186005770745 1.0657950564161998 0.35909110982626735 0.05084172260151768 408.3715168775005 482069.91257243435 0.018732795154868538 0.014481343988371765 5.731695321792168e-08 7.241716903337709 0.06987645583912527 GFGDGYNGYGGGPGGGNFGGS(ph)PGYGGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GFGDGYNGYGGGPGGGNFGGSPGYGGGR 28 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 GFGDGYNGYGGGPGGGNFGGS(0.999)PGY(0.001)GGGR;GFGDGYNGYGGGPGGGNFGGS(0.999)PGY(0.001)GGGR;GFGDGYNGYGGGPGGGNFGGS(1)PGYGGGR;GFGDGYNGYGGGPGGGNFGGS(1)PGYGGGR 161.38 2.1575e-12 90323700.0 177209.0 178701.0 197764.0 189070.0 209578.0 203606.0 198826.0 167341.0 170560.0 144690.0 True False 207206.98366270983 196441.25428623467 202479.44378414704 178477.0208732101 168512.69536826087 192928.5429321221 179991.76190441585 162948.4760624455 173054.11733218163 170921.1516345903 1.2122957380119603 1.149309213093786 1.1846365522801106 1.0442067536191975 0.9859089630318053 1.128757565035491 1.0530689746885014 0.953354658005175 1.0124792378075673 1.0 17.382971417209212 -4.7045791290521315 0.3926052546641337 0.9929034432957395 1.3968411053840273 0.6696550453999244 0.04907772483216866 3.9707551350834214 0.4626480357850401 0.044129243378883534 0.7701239312411597 1.9743351200607174e-05 4.7045791290521315 0.40393766208828774 GFGDGYNGYGGGPGGGNFGGS(ph)PGYGGGR ddPTM_PC-9_Lapatinib_30min_R1 4 GFGDGYNGYGGGPGGGNFGGSPGYGGGR 28 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 GFGDGYNGYGGGPGGGNFGGS(0.998)PGY(0.002)GGGR;GFGDGYNGYGGGPGGGNFGGS(0.999)PGY(0.001)GGGR;GFGDGYNGYGGGPGGGNFGGS(0.999)PGY(0.001)GGGR;GFGDGYNGYGGGPGGGNFGGS(0.999)PGY(0.001)GGGR 111.67 4.6817000000000006e-11 131986000.0 356808.0 289407.0 339176.0 261072.0 284029.0 311895.0 274003.0 257010.0 299565.0 231614.0 True False 351719.85248942714 288736.895872613 311290.25853722193 280272.10579066083 267322.97264249914 298555.97791275586 288189.53463302465 268951.6228611331 265824.83514070197 271648.1712937447 1.294762452529443 1.0629075634762493 1.145931728730876 1.0317467055119274 0.9840779393778119 1.0990538846290063 1.0608925996464489 0.9900733790337365 0.9785629473399042 1.0 18.05137980941098 -1.5228787452832204 0.6986910857947773 1.0221421766831111 32.19132061973792 0.7164286122472667 0.049235474259695 159.98154127693078 0.8537975929775866 0.019703368238145554 7787.992673386576 0.02999999999980086 1.5228787452832204 31.16917844305481 GFGEYSRS(ph)PTF ddPTM_PC-9_Lapatinib_30min_R1 2 GFGEYSRSPTF 11 1 D6REL5;Q6UWZ7-2;Q6UWZ7 D6REL5 FAM175A BRCA1-A complex subunit Abraxas 1 GFGEYS(0.001)RS(0.998)PT(0.001)F;GFGEYSRS(0.994)PT(0.006)F 92.943 0.035578 13952500.0 99159.0 53625.0 89818.0 67352.0 62587.0 64387.0 45785.0 49019.0 76047.0 50126.0 True False 97744.97447646652 53500.83460721016 82433.51074750623 72305.29075968555 58905.75571077636 61633.31810342787 48155.52327227443 51296.601692657496 67481.78604958851 58790.212311303396 1.662606250831202 0.9100296206435665 1.4021638552861122 1.22988653922217 1.0019653509475548 1.0483601892279242 0.8191078306926906 0.8725364252987206 1.1478404890300764 1.0 15.843288367513855 -6.2570459821269715 2.7841734967839407 0.9634945852658718 1.2896928130468757 0.4019765190853468 0.1917928702520401 0.28987875063146107 4.4999543030575655 0.059596879046188225 0.07508861209655829 5.532915248470626e-07 6.2570459821269715 0.3261982277810038 GFGFGQGAGALVHS(ph)E ddPTM_PC-9_AZD4547_30min_R2 2 GFGFGQGAGALVHSE 15 0 E9PP21;P21291 E9PP21 CSRP1 Cysteine and glycine-rich protein 1 1 GFGFGQGAGALVHS(1)E;GFGFGQGAGALVHS(1)E 156.0 6.4193e-05 68620000.0 95438.0 107475.0 127299.0 178235.0 130552.0 123730.0 102367.0 155413.0 101931.0 118827.0 True False 125785.2987662802 142214.1919618253 125610.93208431112 137145.67445329955 112427.1082915548 115993.14354039347 111477.46468884409 131397.4918854586 107318.86456373904 114666.90289812382 1.0969625549059658 1.2402374910934497 1.0954419183703823 1.1960353945824025 0.9804669477420266 1.0115660282849703 0.9721851891987229 1.1459059987187334 0.9359184023578873 1.0 16.80708951081978 -6.262496455537638 24.99907192827264 1.0133892433867635 1.15869368024266 0.5576644537488509 0.06510145090987977 72.17253870509676 1706825.452845096 0.01876484735451651 0.022502527491214105 5.46391009193553e-07 6.262496455537638 0.14530443685589645 GFGFGQGAGALVHS(ph)E ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GFGFGQGAGALVHSE 15 0 E9PP21;P21291 E9PP21 CSRP1 Cysteine and glycine-rich protein 1 1 GFGFGQGAGALVHS(1)E;GFGFGQGAGALVHS(1)E;GFGFGQGAGALVHS(1)E;GFGFGQGAGALVHS(1)E 193.11 1.5735e-09 68393000.0 166240.0 179605.0 217364.0 228323.0 232314.0 215814.0 215875.0 195970.0 195383.0 179940.0 True False 194381.1486103352 197434.99743190638 222546.78211756056 215530.80254315314 186793.73938000278 204496.33392116608 195425.75720034458 190825.99514737868 198240.10674667923 212561.69759574364 0.9144693084829197 0.9288361904570142 1.0469749942475848 1.0139682030252517 0.8787742170522784 0.9620563640307553 0.9193836867637898 0.8977440305839927 0.9326238404611275 1.0 17.697522129316056 -6.252557180366706 24.989503785302105 0.927546524214909 0.9777540883176309 0.17073707818422523 0.04722361218031397 1111.6161396154207 3127461.8510136353 0.01450027925110107 0.01845014866646644 5.590399180422039e-07 6.252557180366706 0.05020756410272187 GFGFGQGAGALVHS(ph)E ddPTM_PC-9_Lapatinib_30min_R1 5 GFGFGQGAGALVHSE 15 0 E9PP21;P21291 E9PP21 CSRP1 Cysteine and glycine-rich protein 1 1 GFGFGQGAGALVHS(1)E;GFGFGQGAGALVHS(1)E;GFGFGQGAGALVHS(1)E;GFGFGQGAGALVHS(1)E;GFGFGQGAGALVHS(1)E 154.23 0.00014798 86214000.0 234417.0 200498.0 225092.0 195692.0 206127.0 208367.0 187641.0 195789.0 217853.0 173826.0 True False 231074.17059318742 200033.7591995608 206585.80464024714 210083.84248937474 194003.01512127405 199455.62913720094 197356.13284553585 204886.07170288492 193316.1010462085 203871.59249141387 1.1334299583838252 0.981175242489879 1.0133133415777265 1.0304713860427734 0.9515941517425708 0.9783394866334852 0.9680413560013152 1.0049760694909653 0.9482248050539462 1.0 17.637301238379138 GFGFGQGAGALVHSE ddPTM_PC-9_Lapatinib_30min_R1 2 GFGFGQGAGALVHSE 15 0 E9PP21;P21291 E9PP21 CSRP1 Cysteine and glycine-rich protein 1 0 ; 128.03 8.7999e-05 10322400.0 44910.0 40369.0 46448.0 44159.0 54455.0 53132.0 44998.0 44403.0 45889.0 44192.0 False True 44269.57516451468 40275.52806076394 42629.22473446495 47406.60017010563 51252.063962649176 50859.66821674137 47327.77626309504 46466.125481121 40720.497587407335 51830.52831786137 0.8541216267953592 0.7770618854927734 0.8224732820208289 0.9146462848955524 0.988839312004218 0.9812685663714249 0.9131254841325892 0.8965010967312148 0.7856469711765335 1.0 15.661514478996043 -5.7641767668070285 4.752513140077145 0.9265655703142348 0.8121344754962849 0.4037978199803097 0.060188339875704044 0.19139559881463625 11.163877289916663 0.017756685129524805 0.029155545975341857 1.7211678815880136e-06 5.7641767668070285 -0.11443109481794989 GFGFVCFSS(ph)PEEATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GFGFVCFSSPEEATK 15 0 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YAR2;Q9H361;Q13310-3;Q4VXU2;Q13310-2;Q13310;B1ANR0;H0Y5F5;H0YB86;A0A6I8PLA1;A0A6I8PS38;H0YEU6 A0A087WTT1 PABPC1;PABPC3;PABPC4;PABPC1L Polyadenylate-binding protein;Polyadenylate-binding protein 1;Polyadenylate-binding protein 3;Polyadenylate-binding protein 4;Polyadenylate-binding protein 1-like 1 GFGFVCFS(0.155)S(0.845)PEEATK 106.32 0.0043097000000000005 0.0 12443.0 12947.0 12386.0 10982.0 14300.0 11389.0 12379.0 12258.0 12650.0 8059.1 True False 14549.354139547631 14232.292596257856 12681.329214166572 10366.714144124378 11498.017653408924 10791.740790811347 11206.371503801138 11936.240488424584 12834.982318551221 9520.151034199504 1.528269256157973 1.494965000568877 1.3320512635367947 1.0889232856583622 1.2077558026237478 1.1335682335336779 1.1771211888912452 1.25378688274437 1.3481910394534453 1.0 13.21676874627957 -5.434828794447629 2.96080138581772 1.1836195647659937 1.5150934285146478 0.693990093971155 0.08962738853398418 0.1468427307809627 2.462259282710777 0.02458305898023056 0.05829123647608801 3.6742711736236615e-06 5.434828794447629 0.33147386374865406 GFGFVCFSS(ph)PEEATK ddPTM_PC-9_Lapatinib_30min_R1 1 GFGFVCFSSPEEATK 15 0 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YAR2;Q9H361;Q13310-3;Q4VXU2;Q13310-2;Q13310;B1ANR0;H0Y5F5;H0YB86;A0A6I8PLA1;A0A6I8PS38;H0YEU6 A0A087WTT1 PABPC1;PABPC3;PABPC4;PABPC1L Polyadenylate-binding protein;Polyadenylate-binding protein 1;Polyadenylate-binding protein 3;Polyadenylate-binding protein 4;Polyadenylate-binding protein 1-like 1 GFGFVCFS(0.135)S(0.865)PEEATK 72.434 0.019648 1862600.0 14674.0 14526.0 16684.0 14142.0 17576.0 17353.0 16545.0 14402.0 15119.0 12481.0 True False 14464.746069117964 14492.365939474787 15312.305922102421 15182.049856329038 16542.214235745516 16610.852641818747 17401.61914469327 15071.169497085897 13416.139009871902 14638.32422011288 0.9881422116094122 0.9900290307521985 1.0460422717692985 1.0371439809666934 1.1300620198736078 1.134750972313869 1.1887712611791763 1.029569318896373 0.9165078466726602 1.0 13.837462784420593 -2.178691708934444 21.161466935731042 1.0538733091290489 0.24042201857400525 0.0 0.07851339108557576 0.0 0.0 0.01947314135534377 0.0 0.006626867558434671 2.178691708934444 -0.8134512905550436 GFGFVCFSSPEEATK ddPTM_PC-9_Lapatinib_30min_R1 2 GFGFVCFSSPEEATK 15 0 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YAR2;Q9H361;Q13310-3;Q4VXU2;Q13310-2;Q13310;B1ANR0;H0Y5F5;H0YB86;A0A6I8PLA1;A0A6I8PS38;H0YEU6 A0A087WTT1 PABPC1;PABPC3;PABPC4;PABPC1L Polyadenylate-binding protein;Polyadenylate-binding protein 1;Polyadenylate-binding protein 3;Polyadenylate-binding protein 4;Polyadenylate-binding protein 1-like 0 ; 145.09 0.0002229 11562600.0 51122.0 42085.0 42306.0 41030.0 47734.0 40877.0 40717.0 43249.0 38696.0 36451.0 False True 50392.9909053734 41987.55476819471 38827.76398588259 44047.48307206762 44926.379968654765 39128.785998941086 42825.127030188916 45258.50642823691 34337.64899305529 42751.50678209554 1.1787418666253453 0.9821304072907957 0.908219777697842 1.0303141663889808 1.0508724335178303 0.9152609801189122 1.0017220503704962 1.0586411996872895 0.803191549904295 1.0 15.383687648407589 -4.76254162874907 6.568120439162347 0.9751415794010879 1.1841489266172693 0.4120581770463553 0.07396556401427715 0.11563096573918517 24.25007580539648 0.01767822545606959 0.10841800278406284 1.727660369867987e-05 4.76254162874907 0.20900734721618142 GFGFVDFNS(ph)EEDAK ddPTM_PC-9_Lapatinib_30min_R1 1 GFGFVDFNSEEDAK 14 0 P19338;H7BY16 P19338 NCL Nucleolin 1 GFGFVDFNS(1)EEDAK 133.47 0.00017348 0.0 4403.1 5007.1 4597.1 4064.1 4872.4 2616.2 3755.2 3140.5 5128.3 2918.8 True False 4340.31098657035 4995.506367585308 4219.144183319175 4362.987471440164 4585.81501150697 2504.3112246600704 3949.625881665283 3286.4190949589115 4550.6968506069215 3423.3106909434728 1.267869433543629 1.4592617552362839 1.2324748070577165 1.2744935722552586 1.3395848129236287 0.7315465789550863 1.153744500057854 0.9600119275335673 1.329326275481218 1.0 11.74117651827264 GFGFVDFNSEEDAK ddPTM_PC-9_AZD4547_30min_R2 1 GFGFVDFNSEEDAK 14 0 P19338;H7BY16 P19338 NCL Nucleolin 0 112.51 0.0034905 0.0 6238.8 5547.3 6007.9 7834.4 7446.6 7405.6 6231.9 7976.8 4491.4 7051.9 False True 8222.608624898563 7340.356241636044 5928.2313205078735 6028.300120273403 6412.7681276724215 6942.5266613007 6786.527027210016 6744.1688486286475 4728.806234625167 6805.015127431306 1.2083159950303237 1.078668614864169 0.8711562295594202 0.8858613841978203 0.9423591289051335 1.0202073810703343 0.9972831654485582 0.9910586122641544 0.6949001796576686 1.0 12.732382653481125 -5.008689586861733 3.3716872720238573 0.9306959483535711 1.1996836541842566 0.500918009347284 0.09115625461986218 0.20273816383896814 4.652781216097328 0.023848787175124203 0.10576764422900715 9.801903287422736e-06 5.008689586861733 0.26898770583068554 GFGFVDFNSEEDAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GFGFVDFNSEEDAK 14 0 P19338;H7BY16 P19338 NCL Nucleolin 0 ;; 180.09 0.00023327 9805500.0 36383.0 36314.0 36314.0 38758.0 41629.0 37500.1 46880.0 39391.0 34343.5 33918.5 False True 42541.92330299456 39919.013929134795 37179.86348161193 36586.5149151314 33472.09628627691 35533.52874084684 42439.18701819189 38357.027988214424 34845.7087159813 40067.65555130172 1.0617522467348968 0.9962902341022521 0.9279271015497194 0.913118434600868 0.835389438831029 0.8868382302865341 1.0591881764545399 0.9573065221922693 0.8696717648320013 1.0 15.290150476454112 -4.9809610919715706 2.3414407090092038 0.9283640465362417 1.0686856030994956 0.3172014835638094 0.06101676693032311 0.4955293025280489 4.4501430403276085 0.017455524197570085 0.12053913152800114 1.0448138189015385e-05 4.9809610919715706 0.14032155656325385 GFGFVDFNSEEDAK ddPTM_PC-9_Lapatinib_30min_R1 4 GFGFVDFNSEEDAK 14 0 P19338;H7BY16 P19338 NCL Nucleolin 0 ;;; 204.85 4.7842e-10 41172200.0 94717.0 75434.0 77919.0 70606.0 79896.0 68888.2 76240.0 74044.8 70798.0 76518.3 False True 93366.31821102931 75259.33720765132 71512.80059603792 75798.60077471138 75196.67436157964 65942.01227223758 80187.33415481492 77485.191721832 62823.983704008955 89744.38620077404 1.0403583127991134 0.8385966007866262 0.7968498490373667 0.8446054843490324 0.837898363841404 0.7347759014665681 0.893508079440442 0.8633987595445128 0.7000324629048174 1.0 16.453534076105107 -4.7624527052260355 5.559664018592562 0.8274621442122113 1.0502452087811285 0.3806948490013573 0.07848156313067527 0.1431829215515907 14.381642193747743 0.01815860925955858 0.1227431185285971 1.728014151420166e-05 4.7624527052260355 0.22278306456891717 GFGFVSFER ddPTM_PC-9_AZD4547_30min_R2 2 GFGFVSFER 9 0 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YAR2;Q9H361;H0YAP2 A0A087WTT1 PABPC1;PABPC3 Polyadenylate-binding protein;Polyadenylate-binding protein 1;Polyadenylate-binding protein 3 0 ; 143.61 0.0027406999999999996 6616200.0 22278.0 22661.0 33280.0 38379.0 42072.0 30178.0 26862.0 35822.0 28165.0 24539.2 False True 29361.940588813555 29985.725089992306 32838.685455234285 29531.314499639175 36231.02901558219 28290.96488937191 29252.665961410716 30286.53300766918 29653.744400012874 23680.090077151162 1.2399420987483822 1.2662842494389592 1.3867635362975337 1.2470946860178476 1.5300207430604915 1.194715256453765 1.235327478320554 1.2789872381816887 1.252264847954513 1.0 14.531386948422229 -9.539103405993025 0.5113607160047572 0.9704087977394223 1.315326955624178 0.49842111623673135 0.0902479633929608 3.660238724122424 1.1640541415322745 0.31316539014736844 0.04422508930288605 2.8899916902442304e-10 9.539103405993025 0.34491815788475566 GFGFVSFER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GFGFVSFER 9 0 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YAR2;Q9H361;H0YAP2 A0A087WTT1 PABPC1;PABPC3 Polyadenylate-binding protein;Polyadenylate-binding protein 1;Polyadenylate-binding protein 3 0 97.602 0.021797 3301900.0 14019.0 11040.0 15518.0 15396.0 20388.0 17383.0 17620.0 14586.0 16538.0 11256.0 False True 16392.139812128764 12135.978239181804 15888.007972342715 14533.412034505474 16393.11775648259 16471.40487897741 15950.906042247041 14203.132955144461 16779.836963177855 13296.623697553036 1.2328046716961234 0.9127112652977595 1.1948903972717955 1.09301521687645 1.2328782200175672 1.2387659644762772 1.199620776301466 1.0681758977475049 1.2619622352902888 1.0 13.698772340075331 GFGFVSFER ddPTM_PC-9_Lapatinib_30min_R1 2 GFGFVSFER 9 0 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YAR2;Q9H361;H0YAP2 A0A087WTT1 PABPC1;PABPC3 Polyadenylate-binding protein;Polyadenylate-binding protein 1;Polyadenylate-binding protein 3 0 ; 143.61 0.0027406999999999996 11926000.0 49898.0 42797.0 42519.0 39160.0 50356.0 45109.0 44447.0 29554.0 38288.0 38516.0 False True 49186.44536982746 42697.90617593986 39023.25194808638 42039.95703393048 47394.15908370515 43179.793224214925 46748.24817915876 30927.186732181395 33975.60224948578 45173.439280655984 1.0888355226671862 0.9451993661732064 0.8638539055138266 0.9306344104716571 1.0491598567302383 0.9558668525534479 1.0348613903120973 0.6846321029495961 0.7521145786221927 1.0 15.463187137120698 -7.753015789648613 24.999962225231112 0.7887799947379477 0.9749980189633047 0.3806128891945745 0.09717138242269574 165.62561254664578 491556.04689632973 0.04581040005421538 0.02589299706178078 1.765973613999495e-08 7.753015789648613 0.18621802422535705 GFGFVTFDDHDPVDK ddPTM_PC-9_AZD4547_30min_R2 2 GFGFVTFDDHDPVDK 15 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ; 164.93 1.0274e-05 82779000.0 135067.0 134437.0 159936.0 170503.0 169540.0 154178.0 158537.0 165902.0 162326.0 144365.0 False True 178015.49643187388 177891.1311911786 157815.14413967408 131196.16759509037 146002.29747342196 144537.22528708278 172646.4858731356 140265.65794870025 170906.22096490287 139310.82529128634 1.2778296019685447 1.2769368842602455 1.1328275732319932 0.9417514203994632 1.0480326792131507 1.0375161082052922 1.2392898076093326 1.0068539731597845 1.2267978501136105 1.0 17.087947842837202 -5.348930036475776 3.8985513348775145 1.0742679928065193 1.2790932012840737 0.44704259412017533 0.08993772862580973 0.19899218257588866 5.54524611864908 0.0237942531002654 0.05508121536074075 4.4778543524205954e-06 5.348930036475776 0.20482520847755437 GFGFVTFDDHDPVDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GFGFVTFDDHDPVDK 15 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;;; 161.04 0.0001392 79118900.0 344519.0 376711.0 363818.0 400569.0 431150.0 347993.0 406008.0 334394.0 322132.0 319342.0 False True 402839.26213958167 414108.3784837332 372492.80090744846 378126.4175922201 346669.2525361712 329743.6344733354 367547.9829966304 325616.5118197298 326842.57108612946 377236.1766901192 1.067870175321213 1.097743016370094 0.9874259785360745 1.0023599033102073 0.9189713870442038 0.8741039562178667 0.9743179623479029 0.8631635350477206 0.866413645567759 1.0 18.52510851054729 -5.731006328616432 1.1015258645779218 0.9078116927118197 1.0915069143246814 0.6478430063373108 0.046682693759214286 0.3388306005011913 0.7830553381076221 0.0168364172231843 0.049697305208901005 1.8577773830320092e-06 5.731006328616432 0.18369522161286167 GFGFVTFDDHDPVDK ddPTM_PC-9_Lapatinib_30min_R1 4 GFGFVTFDDHDPVDK 15 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;;; 136.83 1.3345999999999999e-05 87296400.0 346031.0 414588.0 451393.0 364993.0 439565.0 403401.0 438484.0 409785.0 375759.0 387673.0 False True 341096.53448568715 413628.04695821065 414281.20996736846 391835.8028009553 413710.65091804083 386148.47960366035 461186.55600131047 428825.1070936922 333437.064502312 454681.7615081984 0.7501874131793976 0.9097089040611375 0.9111454319020414 0.8617803395087139 0.9098905782931458 0.8492719794231238 1.0143062577912414 0.9431324134736818 0.7333416308503058 1.0 18.794497609354096 -4.75984258155775 24.913802481096273 0.9027268708789878 0.7501872172298049 0.2711193718469541 0.07545924354999425 53.356076305869976 832202.5704530082 0.018108697443818395 0.11189818103861872 1.7384308424743873e-05 4.75984258155775 -0.15253965364918298 GFGQSNS(ph)LPTAGSVGGGMGR ddPTM_PC-9_AZD4547_30min_R2 1 GFGQSNSLPTAGSVGGGMGR 20 0 G3V2R1;Q9UPU9-2;Q9UPU9-3;Q9UPU9 G3V2R1 SAMD4A Protein Smaug homolog 1 1 GFGQS(0.002)NS(0.881)LPT(0.09)AGS(0.027)VGGGMGR 103.4 0.00016226 10547000.0 15294.0 12491.0 24388.0 35783.0 27698.0 24286.0 16135.0 26153.0 21505.0 23143.0 True False 20157.17386503791 16528.471475181766 24064.599185163876 27533.782191838993 23852.610802281677 22767.392580796797 17570.983742363263 22111.654786152994 22641.710396672355 22332.77061418096 0.9025827656259728 0.7400994601487755 1.077546516771333 1.2328869833264426 1.068054260456857 1.0194611754235212 0.7867802900910988 0.9900990418140254 1.0138334731426124 1.0 14.44687462324833 -5.2661715037203 24.99289404980906 1.0236881086116516 0.8213411093089226 0.35335032868972016 0.10943643263783953 435.35088776773244 2299333.9542746246 0.031815586203457244 0.06988742729324936 5.417868954711991e-06 5.2661715037203 -0.20234699930272904 GFGQSNS(ph)LPTAGSVGGGMGR ddPTM_PC-9_Lapatinib_30min_R1 1 GFGQSNSLPTAGSVGGGMGR 20 0 G3V2R1;Q9UPU9-2;Q9UPU9-3;Q9UPU9 G3V2R1 SAMD4A Protein Smaug homolog 1 1 GFGQS(0.008)NS(0.615)LPT(0.371)AGS(0.005)VGGGMGR 105.92 0.00012006 5650400.0 20126.0 18729.0 19298.0 17426.0 16867.0 21039.0 16897.0 17814.0 17741.0 16657.0 True False 19838.999549343625 18685.63415120633 17711.392932434224 18707.566171431896 15874.916221797894 20139.211014304412 17771.84398234402 18641.703473204292 15742.821758987848 19536.14025594263 1.0155025142854852 0.9564649877819346 0.9065963235520208 0.9575876261300543 0.8125922528104781 1.030869493690205 0.909690642548395 0.954216300097136 0.8058307092773401 1.0 14.253857842574757 -4.8514012217278975 2.5029079548895115 0.9212995459376521 1.0285862538325734 0.15050128905641158 0.067950247666297 0.8068129039572225 7.29362712113708 0.016754286985905285 0.17616303788879295 1.4079874321785637e-05 4.8514012217278975 0.10728670789492134 GFGS(ph)EEGSR ddPTM_PC-9_AZD4547_30min_R2 3 GFGSEEGSR 9 0 Q9Y5S9 Q9Y5S9 RBM8A RNA-binding protein 8A 1 GFGS(1)EEGSR;GFGS(0.618)EEGS(0.382)R;GFGS(0.996)EEGS(0.004)R 83.869 0.013691 92273900.0 66459.0 64159.0 86602.0 111962.0 101469.0 84488.0 65531.0 97664.0 70886.0 84076.0 True False 87591.57956692544 84897.14205237277 85453.60089525838 86150.89069565658 87381.78083243266 79204.95200388526 71363.13204963168 82572.2728954555 74632.88924336282 81132.52483074265 1.0796111639525279 1.0464008389913146 1.0532594797651162 1.061853934354726 1.0770252868960644 0.9762416758152337 0.8795872210128832 1.0177456336742439 0.9198886562332521 1.0 16.307992765080897 -6.847740784009516 5.0055039743582315 0.9524692505370301 1.0618824558041182 0.6661841425342891 0.03728149140774601 0.12081454996965393 5.17890998890454 0.012622022634980141 0.011190092260584369 1.4199047629382606e-07 6.847740784009516 0.10941320526708809 GFGS(ph)EEGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GFGSEEGSR 9 0 Q9Y5S9 Q9Y5S9 RBM8A RNA-binding protein 8A 1 GFGS(0.944)EEGS(0.056)R;GFGS(0.959)EEGS(0.041)R 77.533 0.02292 45955700.0 50020.0 43924.0 64592.0 66184.0 69643.0 55672.0 61186.0 52962.0 56321.0 44912.0 True False 58487.39805996726 48284.48443639688 66132.11824652401 62475.92505142309 55996.95408645855 52752.46231504521 55390.019131721165 51571.803617877486 57144.588076136184 53054.19007680365 1.1024086500104562 0.9100974751758169 1.2465013253578683 1.1775870098286318 1.0554671366275656 0.9943128382259413 1.0440272304889786 0.9720590125533874 1.0770984910600103 1.0 15.695179075351323 -6.516358590584265 20.610765669336182 1.0182420390123468 1.106214784841516 0.2092607736536073 0.0839154350960401 52.538288455755705 166083.9292371797 0.028255156037790066 0.029412273427914973 3.0453794261108996e-07 6.516358590584265 0.08797274582916925 GFGS(ph)EEGSR ddPTM_PC-9_Lapatinib_30min_R1 3 GFGSEEGSR 9 0 Q9Y5S9 Q9Y5S9 RBM8A RNA-binding protein 8A 1 GFGS(1)EEGSR;GFGS(0.996)EEGS(0.004)R;GFGS(0.925)EEGS(0.075)R 102.53 0.0031473000000000004 95513000.0 82101.0 93210.0 107584.0 76636.0 77137.0 73454.0 77237.0 75061.0 89270.0 65253.0 True False 80930.22468452051 92994.17797180537 98738.85880624945 82272.06709020188 72599.95331717687 70312.54364963713 81235.95393645646 78548.60808365248 79215.47254522555 76531.8941058428 1.057470556949693 1.215103572939086 1.2901661452373654 1.0750036707104162 0.9486235008997935 0.9187351818628142 1.0614653522635673 1.0263512879352048 1.0350648376175218 1.0 16.22377348525164 -5.974350823165636 7.035907087187556 0.9998437619643856 1.190020267202151 0.6240441757133137 0.06572564048162502 0.11563935136386845 21.21538211568324 0.019515125391698307 0.028657608277995534 1.0608382656310998e-06 5.974350823165636 0.1901765052377653 GFGS(ph)LPCILNACSGDAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GFGSLPCILNACSGDAK 17 0 Q8WWL2-4;Q8WWL2-3;Q8WWL2-2;Q8WWL2 Q8WWL2-4 SPIRE2 Protein spire homolog 2 1 GFGS(0.991)LPCILNACS(0.009)GDAK;GFGS(0.991)LPCILNACS(0.009)GDAK 95.954 0.0015995999999999999 12953200.0 62099.0 69784.0 73828.0 94208.0 99573.0 86152.0 88190.0 75036.0 76840.0 78670.0 True False 72611.13418884273 76711.69433361066 75588.33951424902 88929.831186457 80062.38544076131 81634.03745807185 79836.00475969152 73066.38450721363 77963.63963300205 92932.24824862284 0.7813340961534173 0.8254582857866828 0.8133703955168131 0.9569318816923688 0.861513489123489 0.8784252936577543 0.8590775136108322 0.7862328296603585 0.8389298774352787 1.0 16.50389168999226 -12.112413023060249 2.0575043939694972 3.5050162058870553 0.8466126617763723 0.48462267420581173 0.048039962942761985 1848916.8733336178 72849.6455256035 21834889.529868014 0.012824950958103957 7.719460991436965e-13 12.112413023060249 -2.658403544110683 GFGS(ph)VEELCTNSSLGMEK ddPTM_PC-9_AZD4547_30min_R2 1 GFGSVEELCTNSSLGMEK 18 0 Q2NKX8;B5MDQ0 Q2NKX8 ERCC6L DNA excision repair protein ERCC-6-like 1 GFGS(0.644)VEELCT(0.138)NS(0.082)S(0.136)LGMEK 74.141 0.0056558 11380000.0 21668.0 26077.0 43670.0 57399.0 52564.0 43246.0 43897.0 50458.0 41228.0 44981.0 True False 28557.973277601795 34505.88028647145 43090.907266528884 44166.547355709874 45266.39592068507 40541.820783543575 47803.74796024295 42660.87550949057 43407.22791136985 43406.228881150826 0.6579233905759343 0.7949522724250216 0.9927355676189858 1.0175163448693239 1.0428548410558196 0.9340092845787135 1.101310784015189 0.9828284236877366 1.0000230158261794 1.0 15.405614466715384 -5.071453802068875 2.10965359425362 1.0136013029180961 0.6438025609306998 0.8915870463156904 0.040797534787432664 0.11375323825630276 0.8398526959852574 0.010799597948918811 0.06365397393541294 8.48293614604337e-06 5.071453802068875 -0.3697987419873964 GFGS(ph)VEELCTNSSLGMEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GFGSVEELCTNSSLGMEK 18 0 Q2NKX8;B5MDQ0 Q2NKX8 ERCC6L DNA excision repair protein ERCC-6-like 1 GFGS(0.937)VEELCT(0.052)NS(0.006)S(0.006)LGMEK;GFGS(0.999)VEELCTNSSLGMEK 152.89 2.5553e-05 18106100.0 47092.0 56665.0 67567.0 79976.0 89882.0 85051.0 93667.0 83665.0 80938.0 67419.0 True False 55063.745490603316 62290.326714061295 69178.05352927437 75495.20400569032 72270.26732333569 80590.77583627154 84794.18366964567 81468.88240039522 82121.56513034756 79641.53101148954 0.6913948638513681 0.7821337174579798 0.8686178260346898 0.947937628105102 0.9074444753317157 1.0119189675628544 1.0646980613345163 1.0229447044236513 1.03113996036189 1.0 16.281233334930477 -4.785961847496786 0.51668217165276 1.037974145251974 0.44513570093394267 0.934364274374825 0.029427586656173763 1.0298572698937014 0.2115578858259762 0.01898021374097894 0.3724806792120967 1.6369603210691e-05 4.785961847496786 -0.5928384443180312 GFGS(ph)VEELCTNSSLGMEK ddPTM_PC-9_Lapatinib_30min_R1 2 GFGSVEELCTNSSLGMEK 18 0 Q2NKX8;B5MDQ0 Q2NKX8 ERCC6L DNA excision repair protein ERCC-6-like 1 GFGS(0.92)VEELCT(0.034)NS(0.023)S(0.023)LGMEK;GFGS(0.937)VEELCT(0.005)NS(0.045)S(0.013)LGMEK 93.34200000000001 0.0009209 25296100.0 122376.0 118295.0 147668.0 112652.0 128478.0 117503.0 114677.0 111782.0 129055.0 102227.0 True False 120630.89579899008 118021.09519552313 135527.30705496413 120936.80387605572 120921.17663746659 112477.67060287141 120614.41394112946 116975.79980025363 114519.46689060245 119896.80074108484 1.006122724320981 0.9843556664233913 1.130366333524054 1.0086741525090128 1.008543813429967 0.9381206996987775 1.0059852572846735 0.9756373737849848 0.9551503141264407 1.0 16.87143363763807 -6.35439956283571 2.774048811932757 0.9757437884440481 1.0370143461069652 0.29989670955532954 0.040887337804285724 0.34723773599412705 5.204321980967826 0.013715781810395695 0.016186934481685605 4.4218136617733496e-07 6.35439956283571 0.06127055766291711 GFGSEEGSR ddPTM_PC-9_Lapatinib_30min_R1 2 GFGSEEGSR 9 0 Q9Y5S9 Q9Y5S9 RBM8A RNA-binding protein 8A 0 ; 127.46 0.0062731 8005300.0 46431.0 42979.0 51474.0 41578.0 44736.0 42606.0 35904.0 36498.0 47683.0 33546.0 False True 45768.88542559742 42879.484766121874 47242.00641538604 44635.78482014201 42104.716434359994 40783.84069943692 37762.93344037879 38193.83032249971 42312.438415749835 39344.38140276474 1.1632889829189494 1.0898502718131113 1.2007306947280236 1.1344894297157624 1.0701583029947266 1.0365861463657688 0.9598049859725378 0.9707569152381137 1.075437887372059 1.0 15.263870005088412 -6.548310501885873 1.9016240174526922 1.0004220020452363 1.1479683559742995 0.7380888449133557 0.039104366614668866 0.1726574631434116 1.264324754134583 0.014896857491420414 0.01588430857406496 2.8293683957130206e-07 6.548310501885873 0.14754635392906312 GFGSSAPEGLEPDS(ph)MASAASALHLLSPR ddPTM_PC-9_Lapatinib_30min_R1 1 GFGSSAPEGLEPDSMASAASALHLLSPR 28 0 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 GFGSSAPEGLEPDS(0.352)MAS(0.352)AAS(0.032)ALHLLS(0.265)PR 78.202 1.3463e-05 5321800.0 15089.0 13660.0 21976.0 14752.0 28928.0 31682.0 31422.0 22120.0 36221.0 29169.0 True False 14873.828093016295 13628.371109267904 20169.21810981317 15836.911291229391 27226.511914636234 30327.03471434917 33048.877410973204 23147.775953030134 32141.40955596073 34210.82278475063 0.43476966884427753 0.3983643186548179 0.5895566510257548 0.4629210876006363 0.7958449899302735 0.8864748709834408 0.9660357372551894 0.6766214334765485 0.939509983673578 1.0 15.062165181498147 -6.3349888844266395 3.165902383347974 0.8766422355823676 0.4700168817073442 0.8177334505152425 0.09451664622941906 0.1098025085763464 2.156021759097615 0.03053080053303335 0.036073707800417625 4.623928559865089e-07 6.3349888844266395 -0.40662535387502347 GFGSSAPEGLEPDSMASAASALHLLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 GFGSSAPEGLEPDSMASAASALHLLSPR 28 0 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 GFGSSAPEGLEPDSMASAASALHLLS(1)PR;GFGSSAPEGLEPDSMAS(0.003)AAS(0.002)ALHLLS(0.995)PR 116.96 2.2307e-12 8745100.0 13917.2 15488.3 29055.0 34514.0 35322.0 35475.0 33087.0 67099.0 42831.0 42328.0 True False 18342.580104256947 20494.59008478567 28669.711715800255 26557.330535984423 30418.15000210103 33256.742642006364 36031.67890198779 56730.39133162847 45094.95921878046 40846.109603640514 0.4490655360387643 0.5017513365081662 0.7018957740162601 0.6501801712253505 0.7447012774844519 0.8141960878213546 0.8821324540238803 1.388881141487517 1.1040209130409142 1.0 15.317911054669105 -7.023626672818563 0.9318287519850101 1.1811800158019994 0.5559065571610806 0.7716192064929237 0.12892319123467869 0.26110992546417183 0.4672975932773919 0.08999214502611302 0.06386123983874452 9.470509131937023e-08 7.023626672818563 -0.6252734586409188 GFGSSAPEGLEPDSMASAASALHLLS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GFGSSAPEGLEPDSMASAASALHLLSPR 28 0 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 GFGSSAPEGLEPDSMASAAS(0.001)ALHLLS(0.998)PR;GFGSSAPEGLEPDSMASAAS(0.002)ALHLLS(0.998)PR 117.83 1.9907e-12 10922600.0 21280.0 25943.0 52827.0 43025.0 60102.0 60789.0 67478.0 49867.0 61907.0 58232.0 True False 24882.283700841737 28518.449588686013 54086.59602751315 40614.44873893203 48325.444545817016 57601.11782708151 61085.995341586065 48558.04408845392 62812.27275846249 68789.00063574166 0.36171892992894134 0.41457862921573374 0.7862680883229844 0.5904206830100307 0.7025170317812103 0.8373594222148489 0.8880198109731916 0.7058983796782177 0.9131150645881929 1.0 16.069890275917142 -4.822924846645342 0.3903965089686565 0.9058107398299255 1.9582162448609624e-31 0.771595228443049 0.09570660205366681 2.8788648073902277 0.3560449785013261 0.08343072359730674 1.2289346317386705 1.5034021027962847e-05 4.822924846645342 -0.9058107398299255 down GFGSSAPEGLEPDSMASAASALHLLS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 GFGSSAPEGLEPDSMASAASALHLLSPR 28 0 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 GFGSSAPEGLEPDSMASAAS(0.001)ALHLLS(0.999)PR 131.16 2.5275e-12 2915600.0 16760.0 15746.0 22989.0 14613.0 25925.0 28712.0 28494.0 24215.0 33763.0 24807.0 True False 16520.999326592417 15709.541104431359 21098.93316010626 15687.688767538983 24400.142470511084 27484.054690941037 29969.27989778725 25340.117301203638 29960.255399848193 29094.856896750247 0.5678322937012875 0.5399422021624047 0.7251774165784918 0.5391911300065965 0.8386410889423024 0.9446361873672205 1.0300542121289715 0.8709483394652477 1.0297440371048743 1.0 14.828476529750853 -6.463860652738427 2.7454077478134176 0.9705498086019001 0.5973883272661428 0.8784341129134411 0.06684541742545216 0.08948589752803804 1.3336493721976876 0.02226352163332868 0.02466930419144596 3.436681992210994e-07 6.463860652738427 -0.37316148133575733 GFGSVEELCTNS(ph)SLGMEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GFGSVEELCTNSSLGMEK 18 0 Q2NKX8;B5MDQ0 Q2NKX8 ERCC6L DNA excision repair protein ERCC-6-like 1 GFGS(0.001)VEELCT(0.046)NS(0.476)S(0.476)LGMEK;GFGS(0.127)VEELCT(0.017)NS(0.594)S(0.262)LGMEK 87.719 0.0014212 25366000.0 88380.0 105925.0 150482.0 177453.0 208111.0 174440.0 187696.0 182708.0 165136.0 142647.0 True False 103340.9884154321 116440.53396606287 154070.0615861628 167510.88372038808 167333.14348731353 165292.05931593064 169916.07607863762 177912.1085951276 167550.80159338115 168507.77190696928 0.613271347938095 0.6910098724131728 0.9143202111248772 0.9940840225035343 0.9930292329762437 0.9809165324860268 1.008357502777058 1.0558095130078053 0.9943209129005844 1.0 17.362455607286485 -5.263000354438558 1.8374729954427125 1.006924500571059 0.599258872617741 0.9819088243348026 0.01897666864442901 0.05158206900506008 0.3049042661800192 0.005956524698070632 0.025638948952220946 5.457574156848505e-06 5.263000354438558 -0.40766562795331795 GFGSVEELCTNS(ph)SLGMEK ddPTM_PC-9_Lapatinib_30min_R1 1 GFGSVEELCTNSSLGMEK 18 0 Q2NKX8;B5MDQ0 Q2NKX8 ERCC6L DNA excision repair protein ERCC-6-like 1 GFGS(0.283)VEELCT(0.24)NS(0.364)S(0.113)LGMEK 84.352 0.0017209 9085900.0 62615.0 54810.0 65863.0 60519.0 65850.0 51968.0 51265.0 54564.0 67919.0 45901.0 True False 61722.09861781534 54683.09081251634 60447.99837853226 64969.76914546577 61976.83246608118 49745.44978332487 53919.250858428546 57099.24263567526 60269.247001223004 53834.92669076206 1.146506597331481 1.0157549043695424 1.1228398011156757 1.2068330568863654 1.1512383553912453 0.9240367330501271 1.0015663468467386 1.0606356532008308 1.1195194403703916 1.0 15.71625483884865 -6.729260004749261 24.999258002323426 1.0237171593074117 1.1263859212014067 0.41117465545880505 0.06424676193926779 226.81075856217916 176202.4627084293 0.022953338355137094 0.022951660861375844 1.8652626553391747e-07 6.729260004749261 0.10266876189399499 GFGSVEELCTNSS(ph)LGMEK ddPTM_PC-9_AZD4547_30min_R2 1 GFGSVEELCTNSSLGMEK 18 0 Q2NKX8;B5MDQ0 Q2NKX8 ERCC6L DNA excision repair protein ERCC-6-like 1 GFGS(0.03)VEELCT(0.233)NS(0.25)S(0.488)LGMEK 135.72 6.6147e-05 12199000.0 30061.0 31026.0 48325.0 57293.0 54610.0 48967.0 44790.0 59239.0 45059.0 51346.0 True False 39619.77269235681 41054.54775350169 47684.17892500592 44084.98401802615 47028.34413721582 45905.08574915084 48776.22323027272 50084.973726796816 47440.72675022834 49548.39216850604 0.7996177263959725 0.8285747721920388 0.9623759084419887 0.8897359144995114 0.9491396608245138 0.9264697347400315 0.9844158628678141 1.010829444403886 0.9574624861466772 1.0 15.59655062266943 -2.7571673848676173 0.34883134906002833 0.9931446569009159 2.851224801115075e-11 0.7942500745784837 0.030588709887750407 11.370165642468677 0.35435891581621143 0.02665287864975463 6.34252561028674 0.0017491723963374169 2.7571673848676173 -0.9931446568724037 GFPTIYFSPANK ddPTM_PC-9_Lapatinib_30min_R1 1 GFPTIYFSPANK 12 0 P30101 P30101 PDIA3 Protein disulfide-isomerase A3 0 97.81299999999999 0.017755 2292900.0 21390.0 22808.0 20338.0 20200.0 22813.0 21968.0 21572.0 18776.0 19712.0 20554.0 False True 21084.97467755441 22755.189477319334 18665.888146950336 21685.575385224613 21471.184192083667 21028.479849909174 22688.892607393354 19648.401505157955 17491.826983437728 24106.73151351653 0.8746509109180631 0.9439350774102498 0.7743019055272782 0.8995651431661573 0.8906717271084583 0.8723073817833249 0.9411849381021148 0.8150587106402704 0.7255992780950061 1.0 14.557148437420839 -10.747090465041977 3.980440442061716 1.0001085458491201 0.8632014735753553 0.2855713626586148 0.06636678166745054 17771919.514360238 15994597.44959669 15004.180066527482 0.01622578086332088 1.7902329034904018e-11 10.747090465041977 -0.13690707227376486 GFQFVSS(ph)SLPDICYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GFQFVSSSLPDICYR 15 0 P62633-8;P62633-4;P62633-5;P62633-6;P62633-2;P62633 P62633-8;P62633-2 CNBP Cellular nucleic acid-binding protein 1 GFQFVS(0.065)S(0.467)S(0.467)LPDICYR 127.07 2.1816999999999998e-05 3578900.0 14052.0 18158.0 17954.0 21033.0 25407.0 27484.0 25566.0 27205.0 27780.0 24288.0 True False 16430.726060349065 19960.60623795861 18382.09145092416 19854.589199906037 20428.68073567555 26042.690657183168 23144.203398188878 26490.897576080166 28186.229945403385 28691.22213629779 0.5726743176813738 0.6957042869465669 0.6406869447247644 0.6920091833518528 0.7120184925768934 0.9076884398115647 0.8066649544673359 0.9233101835200686 0.9823990700537106 1.0 14.808321802254264 -6.915054382210333 0.5289709451487127 1.0072403743288627 0.5983822562482553 0.8910449640426309 0.047491554195781785 0.28810684301530903 0.17278195424611972 0.042055433073957725 0.04639196847594682 1.216033719775034e-07 6.915054382210333 -0.40885811808060746 GFRFRY(ph)VCEGPSHGGLPGAS(ph)SEKNK ddPTM_PC-9_AZD4547_30min_R2 1 GFRFRYVCEGPSHGGLPGASSEKNK 25 3 P19838;P19838-2;D6RC45;D6RH30;A0A494C157;A0A494C1E9 P19838 NFKB1 Nuclear factor NF-kappa-B p105 subunit;Nuclear factor NF-kappa-B p50 subunit 2 GFRFRY(0.991)VCEGPS(0.028)HGGLPGAS(0.49)S(0.49)EKNK 45.395 0.042337 0.0 11877.0 14128.0 16000.0 15877.0 14956.0 16085.0 13612.0 20209.0 14735.0 14585.0 True False 15653.638943053187 18694.599711902007 15787.829545785717 12216.80294720474 12879.61755935175 15079.202407235307 14823.441630061909 17086.163406621254 15513.862017901292 14074.383589328501 1.1122077811579691 1.3282712946715942 1.1217421669362762 0.868016909562404 0.9151105963260339 1.0713934511965897 1.0532213745617505 1.213990175710171 1.1022764811998043 1.0 13.780784118047306 -5.520419417846228 24.998601242297568 1.0352115974115141 1.2214313593811783 0.3521701019103005 0.10249667790916195 104.86339614474194 1065916.637998777 0.030207476546543474 0.05350759391388695 3.01703662412762e-06 5.520419417846228 0.18621976196966417 GFS(ph)DSGGGPPAK ddPTM_PC-9_AZD4547_30min_R2 1 GFSDSGGGPPAK 12 0 Q9H307;G3V5F0;G3V579 Q9H307 PNN Pinin 1 GFS(0.993)DS(0.007)GGGPPAK 112.51 0.00094531 13844000.0 20104.0 22379.0 22420.0 32189.0 30539.0 16446.0 22479.0 49056.0 29980.0 28625.0 True False 26496.653810822685 29612.574104802883 22122.69615103224 24768.3233650925 26299.186991511306 15417.629020167344 24479.58745240682 41475.52239473562 31564.681594616937 27622.847462771893 0.9592296321562427 1.0720319165036336 0.8008839849276087 0.8966607587604241 0.9520809549759661 0.5581477087380701 0.8862079655400721 1.5014933724929471 1.1427019476235232 1.0 14.753574425020796 -7.676731717258903 10.194711815767937 1.2410538321383076 0.8705905170567821 0.4496873588194149 0.17145740078471947 0.2957060270762299 33.12773572754545 0.08087059155292954 0.046607371604734306 2.1050784374305515e-08 7.676731717258903 -0.3704633150815254 GFS(ph)DSGGGPPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GFSDSGGGPPAK 12 0 Q9H307;G3V5F0;G3V579 Q9H307 PNN Pinin 1 GFS(0.908)DS(0.092)GGGPPAK 134.08 5.6298e-05 8893900.0 28961.0 31259.0 28638.0 27266.0 34008.0 40093.0 41039.0 39687.0 39616.0 27651.0 True False 33863.52529417655 34362.186936465914 29320.838530219786 25738.374417564693 27344.376528470657 37990.45250030728 37151.48882336981 38645.25830185235 40195.30905389127 32663.90741480445 1.0367260984467643 1.051992540270664 0.8976525116199213 0.7879759788291325 0.8371434617793831 1.1630712767416382 1.137386545693288 1.1831180455874346 1.2305725871508355 1.0 14.995409762940563 -6.772923902642476 24.991651068819248 1.15393443076776 0.9206718247767354 0.5827426652119156 0.09306289984682041 165.93599020625976 361093.72873686516 0.03562596267815321 0.031685448871468146 1.6868485701830347e-07 6.772923902642476 -0.23326260599102455 GFS(ph)DSGGGPPAK ddPTM_PC-9_Lapatinib_30min_R1 2 GFSDSGGGPPAK 12 0 Q9H307;G3V5F0;G3V579 Q9H307 PNN Pinin 1 GFS(0.796)DS(0.204)GGGPPAK;GFS(0.997)DS(0.003)GGGPPAK 115.14 0.00073663 34877000.0 98416.0 95905.0 113692.0 77198.0 171993.0 160376.0 189731.0 159620.0 173860.0 195871.0 True False 97012.56979271598 95682.93786488578 104344.68262381146 82875.39844497891 161876.70989124823 153517.09233471582 199554.3428190872 167036.52792145865 154278.0559730358 229727.0413682977 0.42229495149935664 0.4165070741997986 0.45421158084966745 0.3607559560744672 0.7046480419853054 0.6682586926656043 0.8686584810847856 0.7271086891928678 0.6715711613840779 1.0 17.809561162026647 -6.388106686767511 3.086401517701796 0.7716018118172581 0.41543900713728704 0.7733010408084727 0.09572009413362957 0.12542359071050516 2.2716898225865334 0.03040437738979111 0.03496913528654397 4.091601350028349e-07 6.388106686767511 -0.356162804679971 GFS(ph)FVATGLMEDDGKPR ddPTM_PC-9_AZD4547_30min_R2 2 GFSFVATGLMEDDGKPR 17 1 E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2;Q5SVM6 E9PGT3 RPS6KA1 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 GFS(1)FVATGLMEDDGKPR;GFS(1)FVATGLMEDDGKPR 138.28 1.899e-05 9137600.0 45093.0 59823.0 59103.0 69980.0 69559.0 56887.0 50134.0 54808.0 49922.0 51900.0 True False 59431.63600733328 79159.61484747402 58319.255602785815 53847.19218022221 59901.93352573875 53329.84689713367 54595.828877572974 46338.68296254627 52560.775002217066 50082.99679713052 1.1866629356879537 1.5805686542305597 1.1644521960021208 1.075159148290171 1.1960532986550596 1.064829389366516 1.0901070696452615 0.9252378237318503 1.0494734413582156 1.0 15.61203327039437 -5.770155939726828 0.7702043746807967 1.0165588386742717 1.4107599929595107 0.5149211433679568 0.11774876960869207 0.7247457123849435 0.757802568014392 0.05628870077126026 0.1969279665745236 1.697633982931989e-06 5.770155939726828 0.39420115428523905 GFS(ph)FVATGLMEDDGKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GFSFVATGLMEDDGKPR 17 1 E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2;Q5SVM6 E9PGT3 RPS6KA1 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 GFS(1)FVATGLMEDDGKPR;GFS(1)FVATGLMEDDGKPR 103.73 0.0012747 9439700.0 34320.0 32576.0 35623.0 41343.0 61171.0 67766.0 72667.0 87783.0 67649.0 54261.0 True False 40129.69814910191 35809.929992716156 36472.38742097984 39026.685745814444 49184.98166969769 64212.23166477492 65783.45569647929 85478.78926377687 68638.23864566586 64098.0897701603 0.6260669903424105 0.5586739030932372 0.5690089603568638 0.6088587957262747 0.7673392740105472 1.001780737850752 1.0262935437290297 1.33356219460334 1.0708312664509254 1.0 15.967993742318876 -6.726164970663701 1.4669167245935668 1.142516002031484 0.577290278287726 0.8827219316748909 0.08648566408836189 0.11712595656509482 0.5251707348496457 0.03767485921609461 0.03515442487455554 1.8786030769822574e-07 6.726164970663701 -0.5652257237437579 GFS(ph)FVATGLMEDDGKPR ddPTM_PC-9_Lapatinib_30min_R1 1 GFSFVATGLMEDDGKPR 17 1 E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2;Q5SVM6 E9PGT3 RPS6KA1 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 GFS(1)FVATGLMEDDGKPR 70.986 0.021292 4589200.0 20068.0 12903.0 20356.0 13780.0 21045.0 33510.0 31921.0 26997.0 32021.0 29319.0 True False 19781.826639979514 12873.123896257955 18682.408256432325 14793.42716873243 19807.17447606194 32076.855415625323 33573.71318934745 28251.379177393967 28414.457783921436 34386.7500848882 0.5752746796700905 0.3743629120076472 0.5433025281630963 0.43020719120629075 0.5760118192956687 0.9328260256185712 0.9763560995577175 0.821577471196078 0.8263199550343264 1.0 15.06956515176858 -6.6743665396091245 4.105845810847059 0.9051165432643875 0.4805120936718486 0.8837517239512132 0.0751111506703154 0.0700099772588811 2.213122777063945 0.025544166776108643 0.025130891946857716 2.116574016774943e-07 6.6743665396091245 -0.4246044495925389 GFS(ph)LEELR ddPTM_PC-9_AZD4547_30min_R2 2 GFSLEELR 8 0 P26373;P26373-2;J3QSB4 P26373 RPL13 60S ribosomal protein L13 1 GFS(1)LEELR;GFS(1)LEELR 123.86 0.0032984999999999998 4001200.0 9367.8 16061.2 20379.0 33640.0 37137.0 27912.0 12758.5 30032.0 22212.0 23888.0 True False 12346.565537655433 21252.66880611555 20108.761144597942 25884.81773281904 31981.16858128149 26166.658227587926 13893.981783510493 25391.2444667054 23386.08097330325 23051.68839094132 0.5356035240571486 0.921957144556373 0.8723335490037308 1.122903333319006 1.3873677293785218 1.1351297910946387 0.6027316328365104 1.1014917448165515 1.0145062078183105 1.0 14.492584802396307 -4.4945282931274955 1.3354957437153157 1.0436322895330965 8.438938960913351e-16 0.3853663457476154 0.18888096226158216 2.9318849565393124 2.8357931922720603 0.059376719582286235 4.993329937076563 3.2023714618712134e-05 4.4945282931274955 -1.0436322895330956 GFS(ph)LEELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GFSLEELR 8 0 P26373;P26373-2;J3QSB4 P26373 RPL13 60S ribosomal protein L13 1 GFS(1)LEELR;GFS(1)LEELR 102.06 0.0043946 2836400.0 9569.0 9253.4 17050.5 15842.099999999999 25086.0 25498.0 15955.6 20704.5 17776.9 14638.099999999999 True False 11188.842703635084 10172.016398409856 17457.048584381344 14954.51849778118 20170.578381357773 24160.839993336354 14444.17005945952 20161.028813231078 18036.853531909343 17291.871654864153 0.6470579314349523 0.5882542157053599 1.0095522875032863 0.864829371641474 1.1664774515998588 1.3972368333268297 0.8353155949660555 1.165925193965908 1.0430827785398018 1.0 14.0778064128472 -5.403705880682649 1.3934881502185257 1.0979761781715605 0.5696556467562267 0.5633486373461374 0.1544790117209525 0.3842369488328962 1.2858112854605848 0.048363288842190794 0.20536254043702615 3.947245327486172e-06 5.403705880682649 -0.5283205314153337 GFS(ph)LEELR ddPTM_PC-9_Lapatinib_30min_R1 1 GFSLEELR 8 0 P26373;P26373-2;J3QSB4 P26373 RPL13 60S ribosomal protein L13 1 GFS(1)LEELR 106.88 0.003819 1558600.0 9117.2 6653.7 10649.0 7187.1 11597.0 7160.5 7604.9 8783.2 10420.0 13026.0 True False 8987.187056110286 6638.293766452113 9773.480326328747 7715.663309462769 10914.887260579244 6854.262106940766 7998.6445109385195 9191.299536648026 9246.389872535568 15277.52674394602 0.5882619095837363 0.43451364070317533 0.6397292238550101 0.5050335331613954 0.7144407235225069 0.4486499825409819 0.5235562434284802 0.6016222187462532 0.6052281908915399 1.0 13.899123386074294 -9.180321607444272 1.169280371899398 1.0006986966472988 0.5522043091761616 0.7307612980865077 0.0803220783372715 1.7446081648905933 2.6697205980419065 0.07563177552345186 0.022519879641574817 6.602043667866172e-10 9.180321607444272 -0.44849438747113723 GFS(ph)S(ph)SRKASDGNCT(ph)LPK ddPTM_PC-9_Lapatinib_30min_R1 1 GFSSSRKASDGNCTLPK 17 2 F6Q6H0;I6L8A6;Q99708-3;Q99708;Q99708-2 F6Q6H0 RBBP8 DNA endonuclease RBBP8 3 GFS(0.844)S(0.864)S(0.277)RKAS(0.015)DGNCT(1)LPK 78.975 0.013346 0.0 29281.0 21547.0 38213.0 21984.0 25925.0 34234.0 24338.0 29376.0 37891.0 20609.0 True False 28863.447570522254 21497.10924534373 35071.27464644569 23600.77669647415 24400.142470511084 32769.89162335174 25598.10255325141 30740.916202360437 33623.316570081086 24171.23819023364 1.1941236664567931 0.8893673164840026 1.4509506865319046 0.9763991612978278 1.0094701098254013 1.3557390550473487 1.0590314965161485 1.2717973303817456 1.3910465117863324 1.0 14.561003757706974 -6.749827697591085 24.999484916466407 1.2227295213933902 1.1043139128656394 0.08665512452478152 0.1801715177361386 564.0032934394396 1214273.6850418407 0.057939617668749756 0.05746979855117939 1.7789850662882178e-07 6.749827697591085 -0.11841560852775079 GFS(ph)TWLK ddPTM_PC-9_AZD4547_30min_R2 1 GFSTWLK 7 0 P26038;V9GZ54 P26038 MSN Moesin 1 GFS(0.5)T(0.5)WLK 84.743 0.025644999999999998 0.0 6031.0 6664.6 6137.9 8680.8 9179.9 9811.0 8833.6 8826.9 6893.2 7341.8 True False 7948.732547407071 8818.801616643692 6056.507435567385 6679.575677023054 7905.429341608261 9197.516619047907 9619.77328704928 7462.90542698328 7257.56047925329 7084.765816669996 1.1219471120279259 1.2447555564777628 0.8548634622921218 0.9428082522228814 1.1158349543477213 1.298210393547059 1.3578110464024902 1.0533736216691236 1.024389608217779 1.0 12.790504451042839 -6.516447132712608 24.441281733954764 1.1681435556770088 1.0407115752780995 0.09888424708875643 0.14399946884983336 477.6011209247315 1814979.9691516291 0.0503688457028363 0.05217587113421319 3.0447586102771206e-07 6.516447132712608 -0.12743198039890924 GFS(ph)VVADTPELQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GFSVVADTPELQR 13 0 Q14847;Q14847-2;C9J9W2;Q14847-3 Q14847 LASP1 LIM and SH3 domain protein 1 1 GFS(0.871)VVADT(0.129)PELQR;GFS(0.941)VVADT(0.059)PELQR;GFS(0.983)VVADT(0.017)PELQR 193.0 1.924e-06 53943600.0 157559.4 194282.0 219163.0 214892.0 236811.0 180093.1 197383.0 151988.0 164894.4 141608.1 True False 184231.09448000044 213569.03299499283 224388.6771003058 202852.29792926402 190409.58451198786 170648.70080021667 178685.4533108309 147998.4760445974 167305.6686504433 167280.5275608969 1.1013301856842412 1.2767118570764013 1.3413914959027087 1.2126474066470023 1.1382650885212628 1.0201348793456764 1.068178442023278 0.8847322411194569 1.0001502929833672 1.0 17.351909991383025 -6.657286659663373 1.499770276634166 0.9763274654864175 1.247475700503741 0.7247941006660621 0.06982590875961488 0.20327048727155753 0.9487494341918821 0.030676025676163694 0.030328580002022553 2.2014728830050424e-07 6.657286659663373 0.27114823501732344 GFS(ph)VVADTPELQR ddPTM_PC-9_Lapatinib_30min_R1 1 GFSVVADTPELQR 13 0 Q14847;Q14847-2;C9J9W2;Q14847-3 Q14847 LASP1 LIM and SH3 domain protein 1 1 GFS(0.644)VVADT(0.356)PELQR 198.52 6.754699999999999e-07 70833000.0 153690.0 179840.0 187940.0 165880.0 124580.0 142340.0 124360.0 116690.0 142040.0 103360.0 True False 151498.35241670583 179423.5915293371 172488.2986693798 178079.3685594588 117252.4493337038 136252.45001074628 130798.75230184659 122111.84339778867 126041.95945249044 121225.63828145718 1.249722043656826 1.480079577826252 1.4228697915279511 1.4689909748794288 0.9672248461292604 1.1239573735582271 1.0789693843324042 1.0073103769870357 1.039730219112981 1.0 16.88733532431928 -6.259660594362093 24.999811799220055 1.0430906812298484 1.411995478432056 0.8648266069203758 0.07146015370945707 54.0494784236277 759633.9007040823 0.02113044333268756 0.025887633383346126 5.49970513607155e-07 6.259660594362093 0.3689047972022077 GFSDS(ph)GGGPPAK ddPTM_PC-9_AZD4547_30min_R2 3 GFSDSGGGPPAK 12 0 Q9H307;G3V5F0;G3V579 Q9H307 PNN Pinin 1 GFS(0.221)DS(0.779)GGGPPAK;GFS(0.098)DS(0.902)GGGPPAK;GFS(0.2)DS(0.8)GGGPPAK 146.16 0.00011943 58385000.0 70998.0 72434.0 95338.0 149229.0 116236.0 97983.0 99430.0 166559.0 112660.0 99595.0 True False 93573.88714986012 95846.87397592788 94073.7558272575 114826.55961506689 100098.63777940697 91856.10752055541 108279.07737856715 140821.13369505844 118614.97760005164 96108.2093643587 0.9736305334241466 0.9972808213766624 0.9788316362300714 1.1947632816645712 1.0415201619241499 0.9557571421637561 1.1266371321940576 1.4652352241959605 1.2341815375039074 1.0 16.552372047836784 -7.529651140452051 24.852872752705956 1.269012320469761 1.03000586003821 0.35815360741273905 0.12318384876969195 147.95457600375036 542942.9714724601 0.055757830179863126 0.03228926057469004 2.9535808228556987e-08 7.529651140452051 -0.23900646043155094 GFSDS(ph)GGGPPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GFSDSGGGPPAK 12 0 Q9H307;G3V5F0;G3V579 Q9H307 PNN Pinin 1 GFS(0.283)DS(0.717)GGGPPAK;GFS(0.219)DS(0.781)GGGPPAK 126.5 0.00026178 10697000.0 51108.0 55409.0 48920.0 47897.0 58620.0 54156.0 63750.0 85829.0 61083.0 49659.0 True False 59759.57497098772 60909.63933467614 50086.43833013313 45213.48637416914 47133.831807190996 51315.96402381065 57711.13848996875 83576.07969334244 61976.223317317315 58661.78359957229 1.0187139105573229 1.0383189121975527 0.8538171746025519 0.770748579395373 0.8034844649274294 0.8747767434774145 0.9837944731429803 1.4247108520231186 1.0565008343484665 1.0 15.840133316159811 -7.536554787681516 24.904427470344793 1.1852141602683128 0.8918549731095632 0.45307638163152364 0.1303800566102223 188.4450490388111 343158.75606065965 0.06215385508786622 0.03590683497569817 2.907001208519403e-08 7.536554787681516 -0.29335918715874965 GFSDS(ph)GGGPPAK ddPTM_PC-9_Lapatinib_30min_R1 1 GFSDSGGGPPAK 12 0 Q9H307;G3V5F0;G3V579 Q9H307 PNN Pinin 1 GFS(0.394)DS(0.606)GGGPPAK 112.02 0.0010031 22674000.0 46409.0 26435.0 38021.0 31885.0 90793.0 66799.0 86095.0 76382.0 61644.0 79028.0 True False 45747.1991496317 26373.791381661555 34895.060145304284 34229.92926524192 85452.73424590589 63942.162486074434 90552.57783392975 79930.9865662002 54701.003579902346 92687.88450180918 0.4935618003962401 0.28454410760822535 0.3764791950195299 0.3693031667431549 0.9219407121568076 0.6898653780886146 0.9769623971961756 0.8623671475061017 0.5901634703814459 1.0 16.50009315193347 -6.254915719846737 24.89792984421723 0.8326546153045834 0.37376340593205526 0.7605216673881281 0.1261799524610017 232.78135326030554 888422.9371104757 0.03632872702136075 0.045771498332968286 5.560121477555948e-07 6.254915719846737 -0.45889120937252814 GFSEGLWEIENNPTVK ddPTM_PC-9_Lapatinib_30min_R1 1 GFSEGLWEIENNPTVK 16 0 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 0 100.22 0.015740999999999998 0.0 11362.0 7969.0 10371.0 8336.5 12163.0 8821.2 8672.6 7530.8 10627.0 10056.0 False True 11199.975796464381 7950.5482701139035 9518.336413217716 8949.59401974876 11447.596253378058 8443.93783922154 9121.624792642295 7880.708460537044 9430.075352728925 11794.166201222262 0.9496199735852202 0.6741085494699884 0.8070376702196467 0.758815321664815 0.9706151378629642 0.7159419068002002 0.7734014119367756 0.6681869939835462 0.7995542195896528 1.0 13.525785809158501 GFSLEELR ddPTM_PC-9_AZD4547_30min_R2 2 GFSLEELR 8 0 P26373;P26373-2;J3QSB4 P26373 RPL13 60S ribosomal protein L13 0 ; 113.41 0.017113999999999997 24406000.0 64219.0 60875.0 82683.0 118501.0 89875.0 83465.0 74712.0 87046.0 74735.0 75310.0 False True 84639.30616181964 80551.65327449291 81586.56939588755 91182.42527219935 77397.40760542524 78245.92035560432 81361.22326367784 73595.04081808862 78685.33952547357 72673.41982257982 1.1646528588919107 1.1084059821478953 1.1226466236908585 1.2546874152173686 1.0650029652433897 1.0766786611477601 1.119545818296536 1.0126816791855782 1.082725152023544 1.0 16.149140176954482 -7.381645337780294 0.6184402028786703 1.015688741629158 1.154445115753327 0.46579492419722723 0.051037296716948156 0.7360267487623134 0.5670724670550709 0.04717337668603433 0.03162943222732786 4.152930490831646e-08 7.381645337780294 0.13875637412416908 GFSLEELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GFSLEELR 8 0 P26373;P26373-2;J3QSB4 P26373 RPL13 60S ribosomal protein L13 0 ;; 113.41 0.017113999999999997 19414200.0 77914.0 79079.0 99285.0 100957.0 111469.0 102151.0 86009.0 91753.0 86753.0 75149.0 False True 91103.30132835437 86929.44050509571 101652.33094045921 95300.70659701015 89627.4496369117 96794.021733442 77861.60486876404 89344.58097033948 88021.59850444837 88772.91882084354 1.0262510519927128 0.9792337760182447 1.1450826703761783 1.07353354900204 1.009626030409034 1.0903552909957392 0.8770873584307836 1.006439600692297 0.9915366045594215 1.0 16.43783201286336 -7.233995781688519 24.98033218998289 0.9693024872826715 1.0536237792651821 0.3703534926907849 0.05445068462741576 817.265216879166 743910.8079015348 0.021049956538395125 0.016301626207988296 5.834507713158944e-08 7.233995781688519 0.0843212919825106 GFSLEELR ddPTM_PC-9_Lapatinib_30min_R1 4 GFSLEELR 8 0 P26373;P26373-2;J3QSB4 P26373 RPL13 60S ribosomal protein L13 0 ;;; 138.83 0.013253000000000001 49791000.0 184886.0 167732.0 189029.0 169136.0 183023.0 189303.0 186651.0 163271.0 182628.0 154539.0 False True 182249.49173606007 167343.62685942333 173487.76529304084 181574.82566115557 172257.9469770628 181206.95197684635 196314.87548964305 170857.1667100896 162058.51148190262 181250.8602397263 1.0055096648645583 0.9232708006907722 0.9571693346094037 1.0017873869453684 0.9503841623109028 0.9997577486649064 1.0831114138161484 0.9426557561388136 0.8941116818290438 1.0 17.467628316795512 -4.4392323330198185 21.636698815593054 0.9741291419969621 3.030856997924053 0.03717874105064467 0.049799235752059474 1283.9295736751205 422206.68684633606 0.01253871246610197 35144.34502122519 3.637204058215419e-05 4.4392323330198185 2.056727855927091 GFSQYGVS(ph)GSPTK ddPTM_PC-9_Lapatinib_30min_R1 1 GFSQYGVSGSPTK 13 0 Q9NXC5 Q9NXC5 MIOS WD repeat-containing protein mio 1 GFS(0.066)QYGVS(0.9)GS(0.034)PTK 191.63 9.8813e-06 59305000.0 193710.0 165270.0 171060.0 144210.0 164500.0 147220.0 143870.0 141490.0 171410.0 122740.0 True False 190947.65987793668 164887.32746915866 156996.10711069542 154815.68447045764 154824.4334194436 140923.74378658188 151318.8846386834 148064.14193463966 152104.0007726796 143955.4454592304 1.3264358237286338 1.1454052810795294 1.090588178931781 1.075441668611994 1.0755024440064784 0.9789400000605942 1.051150820699856 1.0285414453222117 1.0566047035418118 1.0 17.135262837762866 -1.5228787452839108 0.6777196853399254 1.0306886624194083 32.64785596319956 0.916932917505285 0.026684353923700683 64.39091703471203 0.37353998169612235 0.010666658609317405 3072.3148552346374 0.029999999999753172 1.5228787452839108 31.617167300780153 GFSQYGVSGS(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 3 GFSQYGVSGSPTK 13 0 Q9NXC5 Q9NXC5 MIOS WD repeat-containing protein mio 1 GFS(0.005)QYGVS(0.171)GS(0.567)PT(0.257)K;GFSQYGVS(0.019)GS(0.979)PT(0.003)K;GFSQYGVS(0.147)GS(0.49)PT(0.363)K 201.72 1.9235e-07 203643000.0 689449.0 620349.0 725723.0 963825.0 919180.0 834400.0 718372.0 850176.0 757532.0 754150.0 True False 908679.4405699332 820864.6826641212 716099.4388410148 741630.0371978083 791567.7232017211 782224.8360955649 782305.7163290341 718800.8343009384 797573.5949877701 727747.4380453944 1.248619222914053 1.127952693133244 0.9839944483546872 1.0190761223285103 1.0876956507435287 1.0748575607445456 1.0749686985229023 0.9877064441910163 1.095948337695172 1.0 19.47307832994499 -4.9114235587042945 3.242652269316215 1.0436143096107813 1.2528951772132602 0.7186756384495854 0.040380295430835586 0.14496448912405557 2.694472302391594 0.010408307667269624 0.06479078503207508 1.226242717838533e-05 4.9114235587042945 0.20928086760247888 GFSQYGVSGS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GFSQYGVSGSPTK 13 0 Q9NXC5 Q9NXC5 MIOS WD repeat-containing protein mio 1 GFSQYGVS(0.012)GS(0.907)PT(0.08)K;GFSQYGVS(0.002)GS(0.557)PT(0.441)K;GFSQYGVS(0.088)GS(0.885)PT(0.027)K 160.8 9.9331e-05 118842100.0 264435.0 261700.0 249207.0 284095.0 299685.0 244626.0 304536.0 282551.0 255725.0 205297.0 True False 309198.62267068075 287679.84648495325 255149.04000281036 268178.07819841773 240963.8755567733 231797.38192053876 275688.145430292 275134.33563753124 259464.494340831 242515.72096984228 1.2749632124225494 1.1862317433875855 1.0520927838510687 1.1058172935179187 0.9936010523076071 0.9558035289158165 1.136784635353907 1.1345010316743351 1.0698873182456339 1.0 17.887718746809092 -5.023493849671883 2.0950545144437864 1.058140975073238 1.2899975885630208 0.6128240469612989 0.057409305475923086 0.3166685272469539 2.215775259175484 0.016981519466864586 0.11580704088365437 9.473406003189033e-06 5.023493849671883 0.23185661348978281 GFSQYGVSGS(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 3 GFSQYGVSGSPTK 13 0 Q9NXC5 Q9NXC5 MIOS WD repeat-containing protein mio 1 GFSQYGVS(0.079)GS(0.889)PT(0.032)K;GFSQYGVS(0.009)GS(0.622)PT(0.369)K;GFSQYGVS(0.003)GS(0.996)PT(0.001)K 196.97 9.0794e-07 179240000.0 544142.0 421423.0 412982.0 396561.0 463641.0 487549.0 405479.0 355830.0 433065.0 313649.0 True False 536382.4352965791 420447.22093565104 379028.2141166212 425725.41882871545 436370.5479332781 466697.6658022294 426472.718596016 372363.16082128 384288.6593233797 367862.8117389782 1.4581045383765951 1.1429457056234997 1.0303520824104546 1.1572939836353842 1.186231752729902 1.2686731327802192 1.1593254468424636 1.0122337701411772 1.044652101436273 1.0 18.488808312118877 -1.5228787452803376 0.16119983275665628 0.9937617608929099 2.1158334215507244 0.4047769181879526 0.10271370059598162 82.44156524026693 0.8585720834502554 0.33308788562751857 21.99860173341145 0.029999999999999995 1.5228787452803376 1.1220716606578145 GFSQYGVSGSPT(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GFSQYGVSGSPTK 13 0 Q9NXC5 Q9NXC5 MIOS WD repeat-containing protein mio 1 GFSQYGVSGS(0.071)PT(0.929)K;GFSQYGVS(0.06)GS(0.205)PT(0.734)K 177.63 0.00033083 81411000.0 185853.0 186373.0 187121.0 214546.0 207707.0 186328.0 211521.0 194142.0 166387.0 158669.0 True False 217314.2421359277 204874.87974375312 191582.67430034393 202525.68318751702 167008.30438717522 176556.63166830258 191484.1996005752 189045.97821045254 168820.09510172173 187434.4336768872 1.1594147237137304 1.0930482501253265 1.0221316891570082 1.0805148190467777 0.8910225357795036 0.941964761782584 1.0216063070389152 1.0085979107571208 0.9006887997578173 1.0 17.516026490035216 -5.153136730699826 0.8891384939217921 0.9670300836334638 1.2006485537264642 0.6083088996577575 0.050564554739096886 0.9938836101485311 0.8971770635544993 0.01950170918214385 0.20214605569193306 7.028510036038156e-06 5.153136730699826 0.2336184700930004 GFSVVADT(ph)PELQR ddPTM_PC-9_AZD4547_30min_R2 4 GFSVVADTPELQR 13 0 Q14847;Q14847-2;C9J9W2;Q14847-3 Q14847 LASP1 LIM and SH3 domain protein 1 1 GFSVVADT(1)PELQR;GFS(0.022)VVADT(0.978)PELQR;GFS(0.284)VVADT(0.716)PELQR;GFSVVADT(1)PELQR 185.66 0.00010922 213611800.0 180426.8 207241.0 280005.0 380784.0 362662.0 330176.0 267269.0 376388.0 275833.0 310678.0 True False 237798.76928942252 274227.6004313624 276291.95074798306 293000.13185415446 312312.6413017935 309530.0425247941 291055.4232313408 318225.88313579955 290412.96925577003 299801.2577830233 0.7931880307904707 0.9146979651093744 0.9215836944484912 0.9773145517161538 1.0417322582676594 1.0324507802726162 0.9708278923965952 1.0614561309349502 0.9686849595072483 1.0 18.193646910402784 -4.504021690069661 0.7523673148509352 1.0153468157707468 0.5839361027334982 0.8128310340916898 0.03208415324228469 1.5728864958655453 0.5091468483842179 0.01238930854599156 0.6300135806803854 3.133129241810311e-05 4.504021690069661 -0.43141071303724865 GFSVVADT(ph)PELQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GFSVVADTPELQR 13 0 Q14847;Q14847-2;C9J9W2;Q14847-3 Q14847 LASP1 LIM and SH3 domain protein 1 1 GFSVVADT(1)PELQR;GFSVVADT(1)PELQR;GFS(0.029)VVADT(0.971)PELQR;GFSVVADT(1)PELQR;GFSVVADT(1)PELQR 185.66 0.00010922 82130000.0 222281.0 266085.0 284130.0 275060.0 319940.0 239143.0 262284.0 218462.0 220747.0 187855.0 True False 259908.78305013097 292500.16030549776 290904.7367690262 259649.2799565517 257250.0537085065 226601.92009280884 237438.56074828174 212727.6039796226 223975.0072627056 221911.62444063782 1.171226535361862 1.3180930068120096 1.3109035522690444 1.1700571369843171 1.1592455075616006 1.0211358718318322 1.0699690083689033 0.9586140632147372 1.0092982187267965 1.0 17.75962571693166 -6.508291533113506 1.2045921822805838 0.9994334798584007 1.270088342405488 0.8318270884954084 0.049774638717979325 0.17147899003599826 0.5210372341250307 0.022229222691321677 0.025511445648310774 3.102476259311505e-07 6.508291533113506 0.27065486254708737 GFSVVADT(ph)PELQR ddPTM_PC-9_Lapatinib_30min_R1 6 GFSVVADTPELQR 13 0 Q14847;Q14847-2;C9J9W2;Q14847-3 Q14847 LASP1 LIM and SH3 domain protein 1 1 GFSVVADT(1)PELQR;GFSVVADT(1)PELQR;GFSVVADT(1)PELQR;GFSVVADT(1)PELQR;GFS(0.006)VVADT(0.994)PELQR;GFSVVADT(1)PELQR 181.71 0.00019355 86635900.0 233813.2 225264.3 243730.5 220775.9 194773.1 187833.1 160557.3 149490.1 180687.9 148909.5 True False 230478.98089191018 224742.7143535471 223691.919116937 237012.49617281242 183316.92919664804 179799.91617334215 168870.17138109767 156435.95578644046 160336.9259740614 174648.30866556312 1.3196748520093493 1.2868301792942671 1.2808135436644181 1.3570844057051334 1.0496347236186787 1.029497036342012 0.9669155840751363 0.8957198439636894 0.9180559903451064 1.0 17.41409314584626 -6.45356857074644 2.2570170651718118 0.9517602766768212 1.3098054022195276 0.9311902978896142 0.04474122536422292 0.07578137304859409 0.7648378552183794 0.016474631391479973 0.018547325185567 3.5190985509863183e-07 6.45356857074644 0.3580451255427064 GFTECEMT(ph)KSSPLK ddPTM_PC-9_Lapatinib_30min_R1 1 GFTECEMTKSSPLK 14 1 Q9NQW6 Q9NQW6 ANLN Actin-binding protein anillin 1 GFT(0.004)ECEMT(0.332)KS(0.332)S(0.332)PLK 56.956 0.044599 27863000.0 142080.0 120580.0 136670.0 132690.0 111150.0 125280.0 105820.0 109750.0 134380.0 106210.0 True False 140053.91314571895 120300.80441841317 125433.52016145638 142448.46524086426 104612.37552930787 119922.06644194397 111298.84181876344 114849.38566207337 119244.70931586646 124568.25698407096 1.1243146250623721 0.9657420544448696 1.0069460968495052 1.1435374363396584 0.8397996252182053 0.9627016492434255 0.8934767533352872 0.9219795511529042 0.9572640109359061 1.0 16.926576955912132 -6.263832193552826 24.994717906985144 0.9251911383533447 1.0495934832886509 0.5062574813689827 0.06292733149275656 183.61846967799053 1918030.0513097455 0.01864346134585266 0.022131693354502074 5.447130831244081e-07 6.263832193552826 0.12440234493530622 GFTECEMTKS(ph)SPLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GFTECEMTKSSPLK 14 1 Q9NQW6 Q9NQW6 ANLN Actin-binding protein anillin 1 GFTECEMT(0.004)KS(0.498)S(0.498)PLK 84.29700000000001 0.015936000000000002 9786800.0 58481.0 35024.0 47811.0 77014.0 69626.0 65206.0 65403.0 84877.0 63769.0 56841.0 True False 68380.67824759989 38500.95125444777 48950.99556422723 72699.15526275666 55983.28511442305 61786.48257139743 59207.55436328511 82649.06868461515 64701.50098590454 67145.82334689154 1.018390643515216 0.5733930918613144 0.7290251742291485 1.0827055450221417 0.8337567747914845 0.920183557094736 0.881775684801787 1.230889198537787 0.9635968070812232 1.0 16.03501004243182 -6.664681537041551 0.6655862801252582 1.0554748253850836 0.7773253281353489 0.23062434151280609 0.15356216434167488 1.0364689052738065 1.0167976686994875 0.11519821958881725 0.13421236667495584 2.1643050010006651e-07 6.664681537041551 -0.2781494972497347 GFTECEMTKS(ph)SPLK ddPTM_PC-9_Lapatinib_30min_R1 2 GFTECEMTKSSPLK 14 1 Q9NQW6 Q9NQW6 ANLN Actin-binding protein anillin 1 GFTECEMTKS(0.982)S(0.018)PLK;GFTECEMT(0.03)KS(0.771)S(0.199)PLK 120.6 0.00018299 39875300.0 356354.0 332359.0 346607.0 335762.0 312719.0 294836.0 246257.0 249222.0 277582.0 253128.0 True False 351272.3266126795 331589.4431555757 318110.31040171196 360455.0575491977 294325.48324920936 282226.5515762849 259006.98251524466 260801.76394964143 246317.79209195476 296880.8375281417 1.183209834415069 1.1169108990543857 1.0715083972759203 1.2141405304241966 0.9913926600982116 0.9506391652830484 0.872427417922159 0.8784728786172322 0.8296857222002616 1.0 18.179524450566 -6.577002699412686 2.219380664862741 0.8909747202041284 1.1391389152151676 0.7899017473719329 0.05790472684204475 0.13092438573419896 1.3075039770796821 0.0206090620229277 0.021413170031233077 2.648483676567802e-07 6.577002699412686 0.24816419501103926 GFTIPEAFR ddPTM_PC-9_AZD4547_30min_R2 2 GFTIPEAFR 9 0 O00299 O00299 CLIC1 Chloride intracellular channel protein 1 0 ; 127.46 0.0062731 21137000.0 66241.0 52575.0 87282.0 105729.0 85792.0 82440.0 73144.0 94469.0 75459.0 79493.0 False True 87304.26010160705 69568.84058983932 86124.58365095439 81354.81254676636 73881.261677715 77285.01376763928 79653.67430129659 79870.98673165937 79447.60868739821 76709.97426578609 1.138108322121367 0.9069073644686148 1.1227299249579772 1.060550643191285 0.9631245791027107 1.0074962807295538 1.0383744104164487 1.0412073201187755 1.0356881155001658 1.0 16.227126556863347 -4.452966935314773 19.20366846708093 1.0237273112052878 3.6556618448519558 0.29420639794774806 0.05474180064236416 102.53996083198926 30609.182244438147 0.012809081337957896 990.0155173661632 3.523976995562081e-05 4.452966935314773 2.631934533646668 GFTIPEAFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GFTIPEAFR 9 0 O00299 O00299 CLIC1 Chloride intracellular channel protein 1 0 125.31 0.0065911 7411800.0 37395.0 36615.0 43521.0 38660.0 50318.0 44353.0 44928.0 36675.0 40871.0 34992.0 False True 43725.23491508347 40249.89521989509 44558.705694311626 36494.00553741112 40458.549110785316 42027.05060100585 40672.094589448076 35712.32011037457 41468.66105466454 41335.77260348039 1.0578061606474458 0.9737303232722478 1.077969586337425 0.8828673867423587 0.9787781033849307 1.0167234807525347 0.9839442213794152 0.8639567585430267 1.0032148534505185 1.0 15.33510323188689 -5.746235341327899 24.99933170834983 0.9596606924948357 1.0302248327054488 0.28765952267785944 0.05387388017614803 330.86887870951 544028.7939337944 0.014485555033808582 0.024966819593269598 1.793761335928291e-06 5.746235341327899 0.07056414021061319 GFTIPEAFR ddPTM_PC-9_Lapatinib_30min_R1 1 GFTIPEAFR 9 0 O00299 O00299 CLIC1 Chloride intracellular channel protein 1 0 127.46 0.0062731 12542000.0 49749.0 46709.0 48104.0 47681.0 42883.0 49025.0 45975.0 46859.0 50617.0 34220.0 False True 49039.57013715077 46600.84818029238 44149.074806809855 51187.61979915321 40360.70625122183 46928.315032856764 48355.36054259734 49036.24020718983 44915.98043936013 40134.88140471616 1.2218690680219186 1.1611059145877136 1.100017572286186 1.2753898356639537 1.005626647908299 1.1692650729333494 1.2048213137840544 1.2217860995455114 1.1191257795539955 1.0 15.292569014114768 -8.543069489122859 19.708278844769836 0.9999999953802688 1.1667744887644627 0.3476375595244301 0.070547850937691 248.32028202294185 242388.21487824724 0.06638761299812114 0.017141207974690233 2.863719724865059e-09 8.543069489122859 0.1667744933841938 GFVLHK ddPTM_PC-9_AZD4547_30min_R2 1 GFVLHK 6 0 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 85.07700000000001 0.016442 0.0 36283.0 38962.0 49094.0 57515.0 55550.0 48993.0 42729.0 51657.0 47836.0 49165.0 False True 47820.239266717064 51555.70455656332 48442.98148255026 44255.80534789196 47837.84136279689 45929.4599650407 46531.79822295881 43674.597609769626 50364.51330087046 47443.74831466133 1.0079355229177664 1.0866701385950843 1.0210614296590084 0.9328058368064436 1.008306532728439 0.9680824470364903 0.9807782874646794 0.9205553768666516 1.0615626945585692 1.0 15.533930374706344 -5.530316205977093 24.334248294638495 0.9787639664103905 1.0489435745383642 0.2979653182283394 0.04111308500018388 123.78796031974234 405013.98805547244 0.010359622319832095 0.017993145001895854 2.9490612593429853e-06 5.530316205977093 0.07017960812797364 GFVLHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GFVLHK 6 0 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 ; 93.595 0.028933999999999998 6353300.0 122471.0 131848.0 142587.0 144431.0 148469.0 137571.0 137955.0 135587.0 134097.0 113921.0 False True 143202.9213874903 144936.9980869243 145986.81484420906 136338.99932161998 119377.56524363425 130356.53458009551 124886.90369229241 132027.98491630153 136057.91493840006 134573.9755018605 1.0641204649966702 1.0770061413911378 1.0848071798413266 1.0131156400275556 0.8870776448302506 0.9686607985976704 0.9280167523219662 0.9810811074276113 1.0110269421038176 1.0 17.038039916743728 -5.964140874724418 4.659715095167511 0.959261820822291 1.0737738348999357 0.6890565223540698 0.03381703583909915 0.10934049346097706 5.586580651320918 0.00992616970406036 0.01467954832135266 1.0860732703256337e-06 5.964140874724418 0.11451201407764477 GFVLHK ddPTM_PC-9_Lapatinib_30min_R1 2 GFVLHK 6 0 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 ; 93.595 0.028933999999999998 8057200.0 153703.0 150181.0 144021.0 142248.0 151104.0 149994.0 138923.0 135550.0 144998.0 122895.0 False True 151511.16703432164 149833.2651215932 132180.14931713694 152709.39244541762 142216.35980189397 143579.10627309157 146115.7531845406 141848.1478496036 128666.79834336964 144137.23700270572 1.0511590910506874 1.0395180887141644 0.9170437290584089 1.059472178189117 0.986673275825485 0.996127782513247 1.01372661376739 0.984118682994741 0.8926686886675532 1.0 17.137083569832953 -8.015301819670901 16.513234665229806 0.9436861173758058 1.006709142950828 0.23427733279090324 0.044958566102089335 11.08386897079494 11954.301730764377 0.026983408235564506 0.011101390043205149 9.653797402179826e-09 8.015301819670901 0.06302302557502215 GFYDPPRR ddPTM_PC-9_AZD4547_30min_R2 2 GFYDPPRR 8 1 P31942;P31942-2;P31942-3 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 0 ; 81.296 0.011443 11830100.0 67808.0 58963.0 83532.0 118351.0 101510.0 86615.0 71355.0 95521.0 71807.0 83177.0 False True 89369.53350598227 78021.63666569069 82424.3111011608 91067.00545472256 87417.08869014426 81198.95035764277 77705.4567670487 80760.42430421442 75602.57142310399 80264.99854710858 1.1134309490273038 0.9720505584996525 1.026902293566789 1.134579294875015 1.0891059648974892 1.0116358540763697 0.9681113582957626 1.0061723760801549 0.9419120761427766 1.0 16.292483383095394 -6.9554949059970825 4.737482638955925 0.9805242239132681 1.06311089823537 0.45707054234093336 0.04543555700942731 0.20891642821342457 10.5220138965347 0.017553154116256228 0.015119433108948248 1.1079115604084368e-07 6.9554949059970825 0.08258667432210198 GFYDPPRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GFYDPPRR 8 1 P31942;P31942-2;P31942-3 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 0 69.19800000000001 0.026274000000000002 2218900.0 12073.0 10814.0 14259.0 14694.0 14959.0 15913.0 16147.0 12955.0 14897.0 12641.0 False True 14116.720447380745 11887.542452763762 14598.988637558636 13870.742818590765 12027.891334080003 15078.494266764523 14617.439265843535 12614.944976957127 15114.840442644856 14932.71323389906 0.945355356810448 0.7960738458284733 0.9776514427677598 0.9288829565883918 0.8054725986952752 1.0097625281207787 0.9788870272188839 0.8447858590306068 1.0121965248975884 1.0 13.86618870265447 -6.782906136946534 24.99915266127542 0.9600355231064609 0.8923842121449198 0.23505121152598174 0.06976138906699036 423.9460782752881 493703.8754542073 0.024317248139471212 0.021465196842889143 1.648518643515739e-07 6.782906136946534 -0.06765131096154109 GFYDPPRR ddPTM_PC-9_Lapatinib_30min_R1 1 GFYDPPRR 8 1 P31942;P31942-2;P31942-3 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 0 77.67399999999999 0.014685 2806700.0 41327.0 37873.0 40683.0 36870.0 38418.0 36973.0 28552.0 33127.0 35411.0 27743.0 False True 40737.66940155641 37785.307395410186 37338.200780921434 39581.54279471442 36158.32877269409 35391.75097827259 30030.282853991066 34666.20135605917 31422.64028563884 32538.340584776182 1.2519897655941459 1.161254898569994 1.1475139822708407 1.2164585557640135 1.1112530056192111 1.087693789609893 0.9229199250573162 1.0653954913815906 0.9657112108642889 1.0 14.989853056768881 -6.78161478385425 1.8018438629233917 0.9941937078121124 1.1879191718935516 0.7871320810469147 0.04683644046760012 0.15459785688004155 1.0367930197908082 0.018811491310600545 0.016940278452811045 1.6534277267436382e-07 6.78161478385425 0.1937254640814392 GGAAGGALPT(ph)SPGPALGAK ddPTM_PC-9_AZD4547_30min_R2 2 GGAAGGALPTSPGPALGAK 19 0 Q9UPR0 Q9UPR0 PLCL2 Inactive phospholipase C-like protein 2 1 GGAAGGALPT(0.662)S(0.338)PGPALGAK;GGAAGGALPT(0.691)S(0.309)PGPALGAK 170.78 9.9069e-08 12226500.0 53737.0 51537.0 80778.0 111682.0 104795.0 80780.0 100612.0 104292.0 82752.0 86656.0 True False 70824.2482009638 68195.32738903562 79706.83094059242 85935.44036969957 90246.0231433716 75728.81383005691 109566.27308872982 88176.06779174336 87126.10177844363 83622.1998160338 0.8469550951395074 0.8155170222627866 0.9531778775964389 1.0276629956967747 1.0792113020455094 0.9056065733340897 1.3102534175108065 1.0544576438520863 1.0419015760183097 1.0 16.351598375836765 -5.556110900741209 1.3340025349133176 1.076378571407725 0.8111482967056817 0.4724551217238423 0.0964825417756176 0.43483015914057577 1.4337940294856177 0.03154655916035612 0.10618475741214646 2.7790035352667466e-06 5.556110900741209 -0.2652302747020433 GGAAGGALPT(ph)SPGPALGAK ddPTM_PC-9_Lapatinib_30min_R1 1 GGAAGGALPTSPGPALGAK 19 0 Q9UPR0 Q9UPR0 PLCL2 Inactive phospholipase C-like protein 2 1 GGAAGGALPT(0.661)S(0.339)PGPALGAK 135.72 0.00020886 3675100.0 35523.0 29899.0 31820.0 33987.0 32661.0 32926.0 34669.0 34654.0 39521.0 26436.0 True False 35016.435505879635 29829.77070248908 29203.88242875207 36486.51735730839 30739.944193996616 31517.831734254825 36463.9911832802 36264.15135064674 35069.728805420156 31005.427376244195 1.1293647102800008 0.9620822296855072 0.9418958195405351 1.1767784044564955 0.9914375254684931 1.0165262794733552 1.176051880878709 1.1696065630893926 1.1310835480464931 1.0 14.920233155160032 -7.251949989421525 24.51424756231551 1.133319378975092 1.0330204001308951 0.19072733805983688 0.081368041000227 719.3689268563824 1858373.5252131342 0.030936969482345127 0.023644096155808845 5.5982206331647496e-08 7.251949989421525 -0.1002989788441968 GGAAGGALPTS(ph)PGPALGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GGAAGGALPTSPGPALGAK 19 0 Q9UPR0 Q9UPR0 PLCL2 Inactive phospholipase C-like protein 2 1 GGAAGGALPT(0.218)S(0.782)PGPALGAK;GGAAGGALPT(0.191)S(0.809)PGPALGAK;GGAAGGALPT(0.215)S(0.785)PGPALGAK 178.85 8.1386e-37 0.0 54810.0 67578.0 80605.0 83447.0 111546.0 106231.0 104346.0 116782.0 107241.0 83207.0 True False 64088.25045315482 74286.69723255701 82526.92889616481 78771.73512882419 89689.36203966079 100660.05935101242 94461.59148038091 113716.59624075724 108809.19674496065 98291.77043375064 0.6520205116902514 0.7557773850724031 0.8396117857271536 0.8014072264769806 0.912480888724169 1.0240944781725956 0.9610325570852211 1.1569289650490429 1.1070021047011136 1.0 16.584783010241132 -6.2306252411186485 0.6317880470463764 1.094580816279382 0.6717361885046257 0.8509609482325121 0.058469142429621944 0.33659372646055963 0.28020043320957055 0.03986982070602457 0.07993242700984146 5.87996524233818e-07 6.2306252411186485 -0.4228446277747563 GGAAGGALPTS(ph)PGPALGAK ddPTM_PC-9_Lapatinib_30min_R1 1 GGAAGGALPTSPGPALGAK 19 0 Q9UPR0 Q9UPR0 PLCL2 Inactive phospholipase C-like protein 2 1 GGAAGGALPT(0.25)S(0.75)PGPALGAK 181.81 2.2386999999999997e-09 4661000.0 47994.0 38799.0 48498.0 36462.0 45275.0 44232.0 38663.0 49961.0 43715.0 39321.0 True False 47309.59675897835 38709.163299303436 44510.68164769381 39143.53711366632 42612.0135140748 42340.300469828086 40664.78096048808 52282.37045159755 38791.35636064227 46117.582458060926 1.0258472850783416 0.8393580330127959 0.9651564387220769 0.8487768661608236 0.9239862812155414 0.9180945360336726 0.8817630672090934 1.1336754371099753 0.8411402830128598 1.0 15.493029266624523 GGAAPEGPNEAEVTSGKPEQEVPDAEEEKSVS(ph)GTDVQEECR ddPTM_PC-9_Lapatinib_30min_R1 1 GGAAPEGPNEAEVTSGKPEQEVPDAEEEKSVSGTDVQEECR 41 2 P49321;P49321-3;P49321-4;E9PPR5 P49321 NASP Nuclear autoantigenic sperm protein 1 GGAAPEGPNEAEVT(0.002)S(0.002)GKPEQEVPDAEEEKS(0.347)VS(0.433)GT(0.217)DVQEECR 43.602 0.0028675999999999997 28681000.0 13436.0 19114.0 17975.0 18881.0 18839.0 15357.0 16000.0 17591.0 17597.0 13645.0 True False 13244.40017613936 19069.74270736065 16497.164885506543 20269.571725169608 17730.92705889906 14700.216908915487 16828.40171139874 18408.34207910275 15615.040555375075 16003.520069180366 0.8275929369842495 1.1915967627700375 1.0308460147637668 1.2665695820386929 1.1079391897689645 0.9185614693123181 1.0515437627879716 1.150268315940916 0.975725370910527 1.0 13.966101648899496 GGAEQFMEETER ddPTM_PC-9_Lapatinib_30min_R1 1 GGAEQFMEETER 12 0 Q99832-3;Q99832;Q99832-2;Q99832-4 Q99832-3 CCT7 T-complex protein 1 subunit eta 0 101.89 0.011886 1640900.0 22053.0 21928.0 19692.0 18321.0 23175.0 19194.0 14874.0 14720.0 17040.0 13952.0 False True 21738.520175975107 21877.227063252296 18072.999773318217 19668.387457064375 21811.892063803058 18373.11736339935 15644.102940959063 15403.944938001972 15120.77576084511 16363.584610128586 1.3284693234341571 1.336945882243364 1.1044645903643602 1.2019608127237726 1.3329531752047854 1.1228051677642148 0.9560315367132832 0.9413551678931874 0.9240503301144535 1.0 13.99820119951492 -7.085876963097036 3.063122293923875 0.9495501852722089 1.2529164667041977 0.8089230160264407 0.06969293908602169 0.11970469403374773 2.170556290332659 0.03056551802900168 0.023450635701364304 8.205839852571001e-08 7.085876963097036 0.30336628143198874 GGAESHTFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGAESHTFK 9 0 P50238;K4DIB9;H3BRQ4 P50238 CRIP1 Cysteine-rich protein 1 0 101.46 0.0029303000000000003 5525600.0 49142.0 49154.0 51167.0 54634.0 61094.0 55171.0 45792.0 52114.0 49886.0 43375.0 False True 57460.770001257726 54033.68427253098 52387.01533192811 51573.03410581787 49123.069266948565 52277.73563700527 41454.25025462974 50746.06271934723 50615.48837496018 51238.54414368891 1.1214364295776973 1.0545515134271501 1.0224142041393394 1.0065280926247815 0.9587132126391434 1.0202814406748588 0.8090442643799374 0.9903884578968403 0.9878400961787382 1.0 15.644941864079145 -4.993710601640731 0.7041885113557057 0.9520979904962694 1.1864350972886974 0.46252927552804535 0.05535207333524997 2.131647064198728 0.9738774216105547 0.024868033935432653 0.3802029940126931 1.014587245295503e-05 4.993710601640731 0.23433710679242803 GGAGAWLGGPAAS(ph)LSPPKGSSASQGGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGAGAWLGGPAASLSPPKGSSASQGGSK 28 1 Q5SXM2 Q5SXM2 SNAPC4 snRNA-activating protein complex subunit 4 1 GGAGAWLGGPAAS(0.706)LS(0.255)PPKGS(0.014)S(0.014)AS(0.006)QGGS(0.005)K 44.625 0.01609 11163000.0 28841.0 21554.0 22857.0 41239.0 43511.0 35083.0 30344.0 34755.0 31236.0 30761.0 True False 33723.211664284616 23693.738674576503 23401.997565655227 38928.512528641906 34985.331896326956 33243.18571990822 27469.596648464496 33842.71807596642 31692.767407293737 36337.725796057995 0.9280495937900162 0.6520424202536873 0.6440138190539688 1.0712974374655269 0.9627826488833886 0.9148394675682903 0.7559525547260435 0.9313383634932311 0.8721725620685884 1.0 15.14918051058495 -5.749440886565664 24.999751095597713 0.9204192687567331 0.73243599814219 0.39478276108212285 0.10628535504678736 236.66628226566394 493107.4418659257 0.02962565603290616 0.05081214013984747 1.780570252387986e-06 5.749440886565664 -0.18798327061454312 GGAGAWLGGPAAS(ph)LSPPKGSSASQGGSK ddPTM_PC-9_Lapatinib_30min_R1 1 GGAGAWLGGPAASLSPPKGSSASQGGSK 28 1 Q5SXM2 Q5SXM2 SNAPC4 snRNA-activating protein complex subunit 4 1 GGAGAWLGGPAAS(0.527)LS(0.467)PPKGS(0.002)S(0.002)AS(0.001)QGGS(0.001)K 64.152 0.0049497 0.0 24868.0 19315.0 17782.0 18358.0 19028.0 19075.0 14683.0 13976.0 17201.0 14909.0 True False 24513.377759767314 19270.277304210053 16320.032600505003 19708.10856049275 17908.810450487363 18259.206715996806 15443.213895529227 14625.375981896437 15263.642245439945 17486.000785006243 1.4018858892415726 1.102040285891659 0.9333199055154437 1.1270792448660933 1.024179895144673 1.0442185689282117 0.8831758665349798 0.83640485676046 0.8729064142858836 1.0 14.093912748433066 -1.5228787452803376 0.6037353703148874 0.9350063985236792 29.09123005512094 0.7151059797921739 0.08380999016947678 104.3707350984991 0.7981052359069046 0.04168225547155481 3880.887195767034 0.029999999999999995 1.5228787452803376 28.15622365659726 GGAGAWLGGPAASLS(ph)PPK ddPTM_PC-9_AZD4547_30min_R2 1 GGAGAWLGGPAASLSPPK 18 0 Q5SXM2 Q5SXM2 SNAPC4 snRNA-activating protein complex subunit 4 1 GGAGAWLGGPAAS(0.007)LS(0.993)PPK 179.17 7.095299999999999e-33 0.0 17354.0 20041.0 12432.0 11847.0 13098.0 17668.0 19304.0 16096.0 19048.0 17083.0 True False 22872.21101437611 26518.861326884777 12267.14355707551 9115.857184325421 11279.56878793724 16563.217166989954 21022.018603196797 13608.733049283765 20054.83839273728 16484.929369660513 1.3874618751155217 1.6086730329394734 0.7441429248494339 0.5529812703415393 0.6842351905187162 1.0047490526391654 1.2752264891038305 0.8255257116436174 1.2165559186226764 1.0 14.008860085286363 -7.0161776917811975 24.52802548548263 1.0755303956234985 0.9763632316077363 0.014016455878578138 0.318639143625651 3653.8403632525933 5539809.141683341 0.13522287839682723 0.10785702617265924 9.63434753212031e-08 7.0161776917811975 -0.0991671640157622 GGAGAWLGGPAASLS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGAGAWLGGPAASLSPPK 18 0 Q5SXM2 Q5SXM2 SNAPC4 snRNA-activating protein complex subunit 4 1 GGAGAWLGGPAAS(0.3)LS(0.7)PPK;GGAGAWLGGPAAS(0.007)LS(0.993)PPK 158.14 1.0479e-05 4349900.0 42596.0 68530.0 45352.0 52621.0 46182.0 30687.1 52308.0 34835.4 37186.0 30122.7 True False 49806.661490651066 75333.20550100808 46433.36367841777 49672.8159695838 37132.968620260894 29077.81445444788 47353.00756287504 33921.007661157266 37729.77490099964 35583.707058837994 1.3997041232464982 2.1170701910411953 1.3049051803860618 1.3959426961178982 1.043538509320043 0.8171665309172942 1.3307497019514127 0.9532735756021306 1.0603104066311333 1.0 15.118929195854653 -5.767914795936257 1.5938300958002314 1.0403604242336892 1.7432670934070214 0.5835525771620963 0.225491656597622 0.2517359107490596 1.2965975472330935 0.06908550306901105 0.15131196903019645 1.706417137472608e-06 5.767914795936257 0.7029066691733321 GGAGAWLGGPAASLS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 3 GGAGAWLGGPAASLSPPK 18 0 Q5SXM2 Q5SXM2 SNAPC4 snRNA-activating protein complex subunit 4 1 GGAGAWLGGPAAS(0.035)LS(0.965)PPK;GGAGAWLGGPAASLS(1)PPK;GGAGAWLGGPAAS(0.033)LS(0.967)PPK 195.38 7.251000000000001e-54 2797300.0 33761.8 40610.8 32638.4 34138.4 43739.0 39341.0 39278.1 35464.1 36254.4 34062.1 True False 33280.35054084414 40516.76818772012 29954.99673986743 36649.05181836399 41166.35801418261 37658.47713835019 41311.727828780684 37111.89155406219 32171.047696243113 39949.68860010469 0.8330565695762878 1.014194843751897 0.7498180283635286 0.917380162464344 1.030455041245922 0.942647576438218 1.0340938634668713 0.9289657280073251 0.8052890729205536 1.0 15.285896637224964 -5.998388426980982 24.999943708566974 0.9580861972730411 0.8727167852421007 0.1830706066467771 0.08596369809395202 97.7094126933743 1515664.287923616 0.024100673504864358 0.03545667872147475 1.0037176774929502e-06 5.998388426980982 -0.0853694120309404 GGAGGGPGGAGGGS(ph)GQR ddPTM_PC-9_AZD4547_30min_R2 2 GGAGGGPGGAGGGSGQR 17 0 Q6VY07-2;Q6VY07 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 GGAGGGPGGAGGGS(1)GQR;GGAGGGPGGAGGGS(1)GQR 123.76 4.1933e-05 2295800.0 3408.4 4962.1 5320.5 9611.7 8643.4 7977.9 6940.7 7306.5 5534.200000000001 7064.9 True False 4492.20030087585 6566.001785845765 5249.946693647054 7395.871064284682 7443.413105944163 7479.040651829817 7558.408854082471 6177.448311666992 5826.72651370678 6817.5600013881985 0.6589161371460088 0.963101429911697 0.7700624112700225 1.0848266920685299 1.0918001608241845 1.0970260108172025 1.1086677422044573 0.9061083892784417 0.8546645005721014 1.0 12.735039777026575 -4.161794189702641 0.886683894906141 1.0155614043344863 2.4160574984358066e-13 0.46379612063847186 0.10755698046968022 5.63545623771541 1.592440905332863 0.0392237613399321 7.216635087439249 6.88978723061934e-05 4.161794189702641 -1.0155614043342447 GGAGGGPGGAGGGS(ph)GQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGAGGGPGGAGGGSGQR 17 0 Q6VY07-2;Q6VY07 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 GGAGGGPGGAGGGS(1)GQR;GGAGGGPGGAGGGS(1)GQR 106.6 0.0045004 0.0 5294.7 2188.95 3234.02 4957.73 6216.3 6553.5 6384.4 4632.08 5960.700000000001 2791.99 True False 6190.988134908207 2406.2544897334237 3311.131301889149 4679.964461277526 4998.260639082926 6209.822923222602 5779.623412946764 4510.492808094445 6047.863960963496 3298.1556856193183 1.87710609353654 0.7295757747959627 1.003934203690386 1.4189640839828142 1.5154714075131255 1.8828167967627456 1.752380410102285 1.3675803200440724 1.833710878881039 1.0 11.687443785793347 -6.02281421459169 3.277140465203451 1.6003556724450865 1.1587006202718935 0.14994942231416641 0.36175814511817594 0.36452607825330463 8.071713954113848 0.10562714833674246 0.15208113960550487 9.488242709099637e-07 6.02281421459169 -0.441655052173193 GGAGGGPGGAGGGS(ph)GQR ddPTM_PC-9_Lapatinib_30min_R1 2 GGAGGGPGGAGGGSGQR 17 0 Q6VY07-2;Q6VY07 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 GGAGGGPGGAGGGS(1)GQR;GGAGGGPGGAGGGS(1)GQR 129.38 3.0336e-05 991170.0 7350.6 4055.05 4327.9 4940.2 4190.7 4357.5 3297.9 4172.5 6179.5 3255.75 True False 7245.77909606505 4045.6607808665276 3972.076768177124 5303.518788024094 3944.211265233203 4171.139882828626 3468.6491252513697 4366.369582460135 5483.499636980183 3818.5020494858177 1.8975449016822536 1.0594889641112797 1.040218576997225 1.3889003382198635 1.0329210811250744 1.0923497823944581 0.908379537394367 1.1434770823412521 1.4360342264890407 1.0 11.89879108271203 -4.758621276395903 24.99989653040815 1.1222360657139219 1.897545941734179 0.6836312142558836 0.1581901023095534 45.334459521206036 402094.9358689815 0.03949743536059064 0.2671415466280384 1.743326466928671e-05 4.758621276395903 0.775309876020257 GGAGGS(ph)PGSSSGSGSSR ddPTM_PC-9_AZD4547_30min_R2 3 GGAGGSPGSSSGSGSSR 17 0 Q8TAE6 Q8TAE6 PPP1R14C Protein phosphatase 1 regulatory subunit 14C 1 GGAGGS(0.872)PGS(0.11)S(0.015)S(0.002)GS(0.001)GSSR;GGAGGS(0.597)PGS(0.092)S(0.186)S(0.082)GS(0.039)GS(0.003)SR;GGAGGS(0.777)PGS(0.157)S(0.063)S(0.003)GSGSSR 170.47 1.3835e-05 19818400.0 18509.8 19534.399999999998 16560.5 16399.02 13570.9 21673.7 17767.600000000002 16677.35 23637.5 23100.199999999997 True False 24395.531372242618 25848.51278398774 16340.896949561526 12618.479301333351 11686.814785785422 20318.44011275697 19348.881979598 14100.24876487778 24886.929993087342 22291.46902915365 1.0943886802766203 1.1595697327162264 0.7330560820460179 0.5660676416090126 0.5242729750336755 0.9114895068684672 0.8679949246185965 0.632540132121258 1.1164329260013885 1.0 14.44420407426463 -5.261022897124292 24.995304784630775 0.7699259855043905 1.1269792344642973 0.3457800933931552 0.18080958133880998 36.48543904373172 2189508.8341423194 0.047290126208574715 0.11055529018504029 5.482480591083179e-06 5.261022897124292 0.35705324895990675 GGAGGS(ph)PGSSSGSGSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GGAGGSPGSSSGSGSSR 17 0 Q8TAE6 Q8TAE6 PPP1R14C Protein phosphatase 1 regulatory subunit 14C 1 GGAGGS(0.622)PGS(0.124)S(0.242)S(0.012)GSGSSR;GGAGGS(0.995)PGS(0.004)S(0.001)SGSGSSR;GGAGGS(0.877)PGS(0.096)S(0.027)S(0.001)GSGSSR;GGAGGS(0.477)PGS(0.141)S(0.374)S(0.008)GSGSSR 189.52 1.4904e-08 32708400.0 20155.0 37282.8 32118.100000000002 18440.5 48132.9 42090.6 25105.5 24695.8 36609.5 42655.7 True False 23566.84342060455 40983.98999055865 32883.91731257254 17407.338569907646 38701.603769913716 39883.29483973348 22727.325291920148 24047.561417363006 37144.844679130474 50388.840747664595 0.4676996547434328 0.8133544924320999 0.6526031721437575 0.34546019141578355 0.7680590225070308 0.7915104663641617 0.45103886008676447 0.47723982255887787 0.7371641047497615 1.0 15.620816645405963 -8.55834526295751 8.343391236588857 0.9999986333832318 0.6042080886038996 0.39615032329143207 0.1527031756392678 0.8379940655450432 196.46121456022436 0.15003274288688476 0.03877287694812621 2.764742808316528e-09 8.55834526295751 -0.3957905447793322 GGAGGS(ph)PGSSSGSGSSR ddPTM_PC-9_Lapatinib_30min_R1 3 GGAGGSPGSSSGSGSSR 17 0 Q8TAE6 Q8TAE6 PPP1R14C Protein phosphatase 1 regulatory subunit 14C 1 GGAGGS(0.935)PGS(0.046)S(0.014)S(0.004)GSGSSR;GGAGGS(0.969)PGS(0.029)S(0.002)SGSGSSR;GGAGGS(0.841)PGS(0.155)S(0.004)SGSGSSR 197.51 2.9045e-12 34639500.0 6269.68 27734.199999999997 22413.8 20630.6 33691.5 16954.4 40646.0 45017.7 32977.8 25008.199999999997 True False 6180.2732134815 27669.983163884157 20571.02388377004 22147.843145664116 31709.832210037574 16229.299834636755 42750.45099759457 47109.38668719368 29263.49289237075 29330.83404866812 0.21070908530001856 0.943375258881894 0.7013446617180035 0.7551044443166738 1.0811091207778827 0.5533187296245232 1.4575259239699603 1.6061386665318118 0.9977040831438467 1.0 14.84013047555973 -7.263970608564427 24.999912503569355 1.3158537401571198 0.7370826033263479 0.4843514750286444 0.2790466587781312 188.07967484875735 1857569.7297960045 0.10963679815201563 0.077769875674607 5.4453950400414546e-08 7.263970608564427 -0.5787711368307719 GGAGGSPGS(ph)SSGSGSSR ddPTM_PC-9_AZD4547_30min_R2 1 GGAGGSPGSSSGSGSSR 17 0 Q8TAE6 Q8TAE6 PPP1R14C Protein phosphatase 1 regulatory subunit 14C 1 GGAGGS(0.123)PGS(0.383)S(0.343)S(0.101)GS(0.046)GS(0.003)S(0.001)R 71.268 0.013599000000000002 13736000.0 10597.0 11604.0 7266.5 10395.0 7377.8 13306.0 8226.4 9147.0 14110.0 11975.0 True False 13966.62556870712 15354.766071412158 7170.141462153246 7998.59335114904 6353.519820097979 12473.973716547895 8958.533663351538 7733.541327149515 14855.82579386408 11555.758894906325 1.208629021748064 1.3287544514432887 0.620482092726405 0.692173783123387 0.5498141556846218 1.0794594998037135 0.7752440791491747 0.669236992350056 1.2855776871921754 1.0 13.49632438777267 -5.2509467160832335 24.939196270789907 0.8136390488019539 1.2686917956079682 0.38417158860190226 0.21893497564822148 658.843865242513 1565947.118708335 0.05506678483742419 0.14235279759274105 5.6111681565371255e-06 5.2509467160832335 0.45505274680601426 GGAGGSPGS(ph)SSGSGSSREDSAPVATAAAAGQVQQQQQR ddPTM_PC-9_AZD4547_30min_R2 3 GGAGGSPGSSSGSGSSREDSAPVATAAAAGQVQQQQQR 38 1 Q8TAE6 Q8TAE6 PPP1R14C Protein phosphatase 1 regulatory subunit 14C 1 GGAGGS(0.033)PGS(0.301)S(0.301)S(0.087)GS(0.087)GS(0.087)S(0.087)REDS(0.016)APVAT(0.004)AAAAGQVQQQQQR;GGAGGS(0.123)PGS(0.514)S(0.123)S(0.056)GS(0.056)GS(0.063)S(0.063)REDSAPVATAAAAGQVQQQQQR;GGAGGS(0.027)PGS(0.253)S(0.253)S(0.22)GS(0.08)GS(0.08)S(0.08)REDS(0.007)APVATAAAAGQVQQQQQR 86.079 1.3972e-10 12057400.0 9503.470000000001 4199.98 13795.68 35952.6 26498.2 16990.89 10459.75 13489.029999999999 10080.3 17867.2 True False 12525.375775544135 5557.541399914655 13612.740269262815 27664.283532132875 22819.382322226164 15928.446962329512 11390.647486779315 11404.610360572822 10613.124078659675 17241.674766352426 0.726459346048432 0.3223318775714492 0.7895254059558314 1.6045009494159141 1.3235014945739945 0.9238340925798164 0.6606462331030891 0.6614560659054545 0.6155506482103155 1.0 14.073612296653959 -11.033004980551167 4.132397005462009 1.0013433400480738 0.8579180723289761 0.016043879377714232 0.3497950584977837 0.004960869955802149 0.0005880835824860839 0.3881090956588779 0.09326385396991958 9.268191944234631e-12 11.033004980551167 -0.1434252677190977 GGAGGSPGS(ph)SSGSGSSREDSAPVATAAAAGQVQQQQQR ddPTM_PC-9_Lapatinib_30min_R1 1 GGAGGSPGSSSGSGSSREDSAPVATAAAAGQVQQQQQR 38 1 Q8TAE6 Q8TAE6 PPP1R14C Protein phosphatase 1 regulatory subunit 14C 1 GGAGGS(0.104)PGS(0.286)S(0.286)S(0.251)GS(0.015)GS(0.017)S(0.017)REDS(0.02)APVAT(0.004)AAAAGQVQQQQQR 53.147 0.00046258 6944500.0 8623.0 3466.9 4342.5 3874.0 2921.6 4280.4 2306.1 990.98 5069.8 2331.7 True False 8500.03443873547 3458.8726060557005 3985.476412534753 4158.906883285154 2749.7572320866025 4097.337270099746 2425.4985741660407 1037.0245485503522 4498.785736639231 2734.731238205046 3.1081790853840943 1.2647943453214614 1.4573557930872358 1.5207735316669997 1.0054945047877608 1.4982595777086503 0.8869239288603835 0.37920528864511316 1.64505589207078 1.0 11.417183340582586 -2.9599510270831284 1.2806885683807308 1.128164675784965 199.99999999929477 0.7064101296120149 0.3690546251679121 82.71260452634185 1.7550448929769893 0.10832273135740615 46845.08230077104 0.0010966018467201478 2.9599510270831284 198.8718353235098 GGAGTGGTGS(ph)PQASLEILAPEDSQVLQQATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGAGTGGTGSPQASLEILAPEDSQVLQQATR 31 0 Q9Y2J4;Q9Y2J4-2;Q9Y2J4-4;Q9Y2J4-3;D6RIC7;D6RBK2;D6RJA4;D6RF61;D6RCL7 Q9Y2J4 AMOTL2 Angiomotin-like protein 2 1 GGAGT(0.071)GGT(0.174)GS(0.746)PQAS(0.009)LEILAPEDSQVLQQATR 68.291 4.4488999999999994e-05 1374800.0 0.0 0.0 747.89 0.0 953.51 734.37 0.0 458.73 0.0 0.0 True False 0.0 0.0 765.7225339886195 0.0 766.6765603288073 695.8583444155005 0.0 446.68882356461154 0.0 0.0 0.0 GGAPDPSPGATATPGAPAQPS(ph)SPDAR ddPTM_PC-9_AZD4547_30min_R2 1 GGAPDPSPGATATPGAPAQPSSPDAR 26 0 O95365 O95365 ZBTB7A Zinc finger and BTB domain-containing protein 7A 1 GGAPDPSPGATATPGAPAQPS(0.5)S(0.5)PDAR 140.73 1.3369e-09 8001700.0 20782.0 33818.0 37597.0 38462.0 31104.0 40182.0 37840.0 43060.0 35352.0 25974.0 True False 27390.243707546608 44749.0071529659 37098.43921455659 29595.18013197639 26785.746494121213 37669.41318790979 41207.686694206765 36406.06642036279 37220.63454746161 25064.658165870293 1.0927834533503826 1.7853428064660037 1.4801095219033265 1.1807533913339046 1.0686659405790129 1.5028895642073017 1.6440554034891206 1.452486053447787 1.4849847263484208 1.0 14.613366938195275 -5.571501054125122 24.999386352971314 1.3588639470243018 1.4874809685523178 0.03419012343165273 0.24818913827594904 382.2900061379095 196554.28591921908 0.06876463948024222 0.1191038990671254 2.682248097213701e-06 5.571501054125122 0.12861702152801602 GGAPDPSPGATATPGAPAQPS(ph)SPDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGAPDPSPGATATPGAPAQPSSPDAR 26 0 O95365 O95365 ZBTB7A Zinc finger and BTB domain-containing protein 7A 1 GGAPDPSPGATATPGAPAQPS(0.5)S(0.5)PDAR 101.86 1.0817e-09 7291600.0 22245.0 32488.0 30409.0 35184.0 29319.0 20265.0 26850.0 22022.0 15922.0 20313.0 True False 26010.639141222935 35713.19393428788 31134.065886774715 33212.75454806707 23574.152418202546 19202.26772550637 24306.57362283389 21443.94583423773 16154.82912853537 23995.58610238047 1.0839759875105766 1.488323468404257 1.2974913700351782 1.3841193295450371 0.9824370331118474 0.8002416629282258 1.0129601968931516 0.8936620986353151 0.6732416978526204 1.0 14.550481431472946 -6.37082344278321 4.0858603120979025 0.8791684805050778 1.324547988712354 0.7133810139006478 0.13135817494462013 0.12152100571540252 3.507315401370355 0.04060191333044114 0.04645320542162792 4.2577147024275696e-07 6.37082344278321 0.4453795082072761 GGAPDPSPGATATPGAPAQPS(ph)SPDAR ddPTM_PC-9_Lapatinib_30min_R1 2 GGAPDPSPGATATPGAPAQPSSPDAR 26 0 O95365 O95365 ZBTB7A Zinc finger and BTB domain-containing protein 7A 1 GGAPDPSPGATATPGAPAQPS(0.5)S(0.5)PDAR;GGAPDPSPGATATPGAPAQPS(0.5)S(0.5)PDAR 108.99 3.0724e-10 20309300.0 68154.0 89004.0 97807.0 95852.0 87510.0 93674.0 89226.0 90196.0 95680.0 87440.0 True False 67182.11146208705 88797.91670638947 89765.68600593819 102901.27583289868 82362.83385127953 89667.78138475932 93845.68569382891 94386.8354366863 84903.51084493315 102553.88749352361 0.6550908317964024 0.8658659254823193 0.8753026160184029 1.003387373680954 0.8031176181057089 0.8743479508801842 0.9150865753358728 0.9203633108754355 0.8278916862151607 1.0 16.64602265529726 -4.718888722900023 2.82573374470595 0.8984638211647629 0.5862027182903353 0.5925748109297289 0.0610882934074026 0.38723267528848304 3.6482407789818048 0.015067779603955665 0.3031957599486845 1.9103426733988464e-05 4.718888722900023 -0.31226110287442754 GGAPDPSPGATATPGAPAQPS(ph)SPDARR ddPTM_PC-9_AZD4547_30min_R2 2 GGAPDPSPGATATPGAPAQPSSPDARR 27 1 O95365 O95365 ZBTB7A Zinc finger and BTB domain-containing protein 7A 1 GGAPDPSPGAT(0.003)AT(0.014)PGAPAQPS(0.561)S(0.422)PDARR;GGAPDPSPGATATPGAPAQPS(0.5)S(0.5)PDARR 127.93 6.375100000000001e-11 23938000.0 70977.0 40557.0 90189.0 178067.0 147932.0 82740.0 63736.0 108501.0 67986.0 89584.0 True False 93546.20958668726 53666.25711463827 88993.03493155421 137016.4042577255 127394.19529219181 77566.25472021435 69408.38052700747 91734.66355494168 71579.60116383014 86447.6914272475 1.082113449673942 0.6207945663858777 1.0294437417851559 1.5849631377725746 1.473656417990109 0.8972623032448752 0.8028945525447612 1.0611580487622805 0.8280105573908817 1.0 16.39953981697476 GGAPDPSPGATATPGAPAQPS(ph)SPDARR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGAPDPSPGATATPGAPAQPSSPDARR 27 1 O95365 O95365 ZBTB7A Zinc finger and BTB domain-containing protein 7A 1 GGAPDPSPGATATPGAPAQPS(0.547)S(0.453)PDARR;GGAPDPSPGATATPGAPAQPS(0.5)S(0.5)PDARR 140.27 4.8253e-12 21692700.0 67627.0 24737.0 54748.0 86343.0 91204.0 106398.0 69734.0 93050.0 91716.0 73829.0 True False 79074.91540586593 27192.725878862326 56053.39995294619 81505.48163778298 73333.23091339218 100818.30157702575 63128.29068956052 90607.53609462449 93057.1729903751 87213.61326995747 0.9066808774577503 0.31179451073413356 0.6427138820569305 0.9345499926197787 0.8408461496303276 1.1559927148638698 0.7238352858303873 1.038915058067387 1.0670028393655668 1.0 16.412265724003248 -5.7414842065145875 4.089986940420777 0.9630339188284228 0.5796420206467975 0.449089130616803 0.17508058241160748 0.172239675082491 6.412244417296805 0.0470552029374687 0.08021904419649038 1.8134926238616632e-06 5.7414842065145875 -0.38339189818162533 GGAPDPSPGATATPGAPAQPS(ph)SPDARR ddPTM_PC-9_Lapatinib_30min_R1 2 GGAPDPSPGATATPGAPAQPSSPDARR 27 1 O95365 O95365 ZBTB7A Zinc finger and BTB domain-containing protein 7A 1 GGAPDPSPGATATPGAPAQPS(0.5)S(0.5)PDARR;GGAPDPSPGATAT(0.005)PGAPAQPS(0.497)S(0.497)PDARR 126.1 3.6883e-11 22920000.0 145895.0 77608.0 96435.0 79469.0 67994.0 75928.0 56205.0 43490.0 95923.0 44620.0 True False 143814.51054613348 77428.30344422128 88506.4865498652 85313.41536081253 63994.72660134728 72680.73643681282 59115.019886822854 45510.70416805066 85119.1416260296 52332.507547587236 2.748091335301665 1.4795450681168645 1.691233435917132 1.6302183739855185 1.2228484664747874 1.3888257957202306 1.1296041916789124 0.8696450122644449 1.6265060784375498 1.0 15.675419767869496 -1.5228787452803414 0.6422606213701916 1.217594516797738 117.37978701840332 0.7337919201428855 0.25781352889917253 109.26945666987437 0.7262408769375447 0.10727757598705133 18014.704005766776 0.029999999999999735 1.5228787452803414 116.16219250160559 up GGAPDPSPGATATPGAPAQPSS(ph)PDAR ddPTM_PC-9_AZD4547_30min_R2 1 GGAPDPSPGATATPGAPAQPSSPDAR 26 0 O95365 O95365 ZBTB7A Zinc finger and BTB domain-containing protein 7A 1 GGAPDPSPGATATPGAPAQPS(0.268)S(0.732)PDAR 123.03 1.2916e-12 7721200.0 26980.0 30207.0 36404.0 33923.0 39444.0 35702.0 27522.0 37547.0 26670.0 35064.0 True False 35559.0787811379 39970.82201991959 35921.25917404894 26102.576455125432 33967.88145300019 33469.54829612155 29971.40468282131 31744.973894225765 28079.721752115885 33836.42003265095 1.0509113773509324 1.1812958339371942 1.0616152400102077 0.771434342933956 1.0038852047652318 0.9891574895873919 0.8857735142754453 0.9381894971038007 0.8298668040241829 1.0 15.046289315786419 -5.539599079197589 24.283960208985935 0.9194220877781546 1.1174416041810873 0.547852970188559 0.07641887312627375 111.04850307206482 161281.75581440146 0.019970510427939063 0.0346031413812585 2.8866951383875987e-06 5.539599079197589 0.1980195164029327 GGASS(ph)SCCEEEQTQGR ddPTM_PC-9_AZD4547_30min_R2 2 GGASSSCCEEEQTQGR 16 0 Q9UJK0 Q9UJK0 TSR3 Ribosome biogenesis protein TSR3 homolog 1 GGASS(0.983)S(0.017)CCEEEQTQGR;GGASS(0.998)S(0.002)CCEEEQTQGR 313.32 5.775199999999998e-147 26435000.0 22719.5 20467.4 29608.2 41249.0 37082.0 34355.0 28604.7 36043.0 22104.1 32371.0 True False 29943.82840504309 27083.086788178327 29215.575922345786 31739.680340697145 31933.804381912414 32206.776419059323 31150.462885353507 30473.38253574398 23272.47759958546 31237.70114296555 0.9585797708992478 0.8669999967099754 0.9352665162085678 1.016069658757352 1.0222840738427263 1.0310226182028763 0.9972072766426447 0.9755321749278695 0.7450124928551669 1.0 14.931000665562097 -12.15206022190348 2.2184053740129612 2.1064583706183835 0.9555384254302497 0.027960366416405535 0.08278486855625612 12896073.211004002 2100455.862952652 75605854.26393424 0.021475530087627013 7.045953587324239e-13 12.15206022190348 -1.1509199451881338 GGASS(ph)SCCEEEQTQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGASSSCCEEEQTQGR 16 0 Q9UJK0 Q9UJK0 TSR3 Ribosome biogenesis protein TSR3 homolog 1 GGAS(0.01)S(0.965)S(0.024)CCEEEQTQGR;GGASS(0.984)S(0.016)CCEEEQTQGR 305.98 1.4649999999999998e-128 24386000.0 11367.599999999999 13776.2 17194.3 14647.8 17946.9 14449.6 15220.0 18362.4 16792.2 11930.8 True False 13291.910159665815 15143.81009226598 17604.27732174588 13827.131254808328 14430.33377789963 13691.837538932983 13778.25141674233 17880.406456571025 17037.754157278705 14093.759595839158 0.943106065438347 1.0745046408154162 1.2490831280351284 0.9810818157342811 1.0238810786981096 0.9714822681504492 0.9776136255942685 1.268675425813974 1.2088863898536122 1.0 13.782768890187258 -7.753941844916516 24.999954695394134 1.1790856876893478 1.0370111834263531 0.234223504091011 0.10358917675718608 223.68519027019906 745868.2382122006 0.05103227434439286 0.02872477157682654 1.7622120031857454e-08 7.753941844916516 -0.14207450426299473 GGASS(ph)SCCEEEQTQGR ddPTM_PC-9_Lapatinib_30min_R1 1 GGASSSCCEEEQTQGR 16 0 Q9UJK0 Q9UJK0 TSR3 Ribosome biogenesis protein TSR3 homolog 1 GGAS(0.082)S(0.459)S(0.459)CCEEEQTQGR 160.46 5.5708e-05 9744900.0 4712.6 7067.0 10161.0 7483.5 8681.7 7926.3 9494.5 10043.0 10294.0 9246.3 True False 4645.397459815006 7050.636795695187 9325.601802594269 8033.861554224178 8171.059474878919 7587.310626107754 9986.078753054704 10509.634443774039 9134.58131937438 10844.5106350797 0.4283639544589617 0.650157211602326 0.8599375404204886 0.7408228756986354 0.7534742460805256 0.6996452750541281 0.9208418055077423 0.9691202118219695 0.8423230541935143 1.0 13.404677331566285 -4.08004837835681 0.28569602295662205 0.9618647182469177 3.111416806533479e-26 0.6948002482338089 0.08960254256180332 8.30756705683323 0.4085036461562585 0.11384149928262403 2.997259512664426 8.316711217022714e-05 4.08004837835681 -0.9618647182469177 GGASSS(ph)CCEEEQTQGR ddPTM_PC-9_Lapatinib_30min_R1 1 GGASSSCCEEEQTQGR 16 0 Q9UJK0 Q9UJK0 TSR3 Ribosome biogenesis protein TSR3 homolog 1 GGAS(0.001)S(0.229)S(0.77)CCEEEQTQGR 157.37 4.519e-05 6545100.0 3750.6 7446.7 10833.0 8928.2 9430.5 10026.0 9545.6 8381.3 11661.0 7332.4 True False 3697.1157562241974 7429.457623673886 9942.352556589285 9584.809611602104 8875.816531076365 9597.211351747515 10039.824461020486 8770.725795439941 10347.615384226221 8599.795570191141 0.42990740024556473 0.8639109573053207 1.156114988483186 1.114539239144852 1.032096223524426 1.1159813362324154 1.167449200283413 1.0198760800595403 1.2032396932891547 1.0 13.070086649898116 -4.831978914698763 2.3751703551319183 1.1025241432877733 0.31246542983313064 0.9088850008513152 0.06503338385603133 0.12481353567784291 0.9498681455468985 0.016185392831395022 0.19804311074463093 1.4723839859710594e-05 4.831978914698763 -0.7900587134546426 down GGCGS(ph)PGLQCK ddPTM_PC-9_AZD4547_30min_R2 4 GGCGSPGLQCK 11 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 GGCGS(1)PGLQCK;GGCGS(1)PGLQCK;GGCGS(1)PGLQCK;GGCGS(1)PGLQCK 96.06700000000001 0.0059581 29860900.0 120209.0 105783.0 148603.0 192175.0 165121.0 140740.0 135302.0 170317.0 134694.0 139767.0 True False 158432.96149747257 139975.2860506888 146632.42712452455 147872.02282415278 142196.79934592915 131939.5055514019 147343.6158852952 143998.42114530687 141813.64985674905 134873.79987176403 1.174675597841154 1.0378241451176966 1.087182442134354 1.0963732241899262 1.0542951965550589 0.9782441488031626 1.0924554363070313 1.0676530303307121 1.051454396566148 1.0 17.041250596880353 -4.756282187730101 24.99251183856039 1.0553952950896173 1.1746757838390738 0.49861182839509066 0.03682356206290581 143.46271850944782 695164.127777349 0.00922974290775143 0.07588013506379221 1.7527412683906298e-05 4.756282187730101 0.11928048874945651 GGCGS(ph)PGLQCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GGCGSPGLQCK 11 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 GGCGS(1)PGLQCK;GGCGS(1)PGLQCK;GGCGS(1)PGLQCK 73.9 0.023586000000000003 13653600.0 67110.0 68169.0 84765.0 92853.0 103596.0 107724.0 114133.0 94616.0 82337.0 77894.0 True False 78470.39751708115 74936.36780677376 86786.11907305285 87650.74744348753 83297.10747010855 102074.76380273624 103321.49598863689 92132.43025393854 83541.02285869968 92015.56559143525 0.8527948180583168 0.8143879497465023 0.9431678055254038 0.9525643501738797 0.90525018169167 1.1093206149051513 1.1228697593122656 1.0012700531888505 0.9079009874224544 1.0 16.489590311393812 -5.728475224242676 1.0015683766217267 1.0240681687831423 0.8229236782096065 0.4930484050099234 0.06787006782770963 0.5858597573746942 1.0913279092898356 0.028801928971699205 0.09138170377778064 1.8686362767184142e-06 5.728475224242676 -0.20114449057353578 GGCGS(ph)PGLQCK ddPTM_PC-9_Lapatinib_30min_R1 2 GGCGSPGLQCK 11 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 GGCGS(1)PGLQCK;GGCGS(1)PGLQCK 116.74 0.0012312999999999998 11600600.0 51591.0 64817.0 62772.0 57349.0 54375.0 58175.0 56856.0 57263.0 56371.0 51398.0 True False 50855.30287936933 64666.920218844636 57611.1284669272 61566.636770655794 51176.76940536314 55686.99086254853 59799.725481455396 59923.64802885918 50021.90436705395 60282.07581646994 0.8436222905495057 1.072738775879657 0.955692512021741 1.0213091692146887 0.8489549955308756 0.9237736111159934 0.991998445168294 0.9940541565174033 0.829797310221146 1.0 15.879441476620618 -6.201140352440188 24.99997906840668 0.9337768217062876 0.9791799127006187 0.0642078358833047 0.07679249119755363 706.7817452466417 293030.81480062444 0.021964811139067654 0.028356444188028622 6.29302776050368e-07 6.201140352440188 0.04540309099433104 GGCLT(ph)MVPS(ph)EKEVEPK ddPTM_PC-9_AZD4547_30min_R2 1 GGCLTMVPSEKEVEPK 16 1 P32298-2;P32298 P32298-2 GRK4 G protein-coupled receptor kinase 4 2 GGCLT(1)MVPS(1)EKEVEPK 69.975 0.039997000000000005 0.0 0.0 0.0 1471.3 2070.7 1387.0 1977.7 1054.0 1500.1 1093.9 0.0 True False 0.0 0.0 1451.7896006696578 1593.3321069960864 1194.438991362723 1854.0341063592953 1147.8039581314456 1268.2940138687 1151.7213207588886 0.0 0.0 GGCPGGEATLS(ph)QPPPR ddPTM_PC-9_AZD4547_30min_R2 1 GGCPGGEATLSQPPPR 16 0 P20290 P20290 BTF3 Transcription factor BTF3 1 GGCPGGEAT(0.022)LS(0.978)QPPPR 73.80199999999999 0.013897 3012400.0 3502.3 3868.7 4979.1 9332.0 7588.0 6881.1 4841.1 6023.9 6109.9 6209.6 True False 4615.958547634516 5119.181618448137 4913.073880713857 7180.651577962754 6534.5371784140925 6450.8237292152235 5271.948521546629 5093.044670451076 6432.856840391934 5992.203794055139 0.7703273630669913 0.8543069952872553 0.819911012637473 1.198332337275757 1.0905064986102446 1.076536104398699 0.8798012722425972 0.8499451696726139 1.0735377269334476 1.0 12.54887097515985 -5.670582992676002 15.420526178349077 1.0167753756037035 0.8185856482790906 0.48893296498573957 0.09781293923266238 1.2047071106058536 201.0803205428337 0.02931846264140726 0.05078168260249781 2.1350940355034613e-06 5.670582992676002 -0.19818972732461282 GGCPGGEATLS(ph)QPPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGCPGGEATLSQPPPR 16 0 P20290 P20290 BTF3 Transcription factor BTF3 1 GGCPGGEAT(0.013)LS(0.987)QPPPR;GGCPGGEAT(0.01)LS(0.99)QPPPR 125.39 0.00020046 0.0 5209.4 4426.3 8443.5 8245.900000000001 8296.0 9342.5 10661.9 6240.9 6739.5 3665.3999999999996 True False 6091.248529660002 4865.713811602392 8644.825062152067 7783.908956568502 6670.458353334296 8852.562853468702 9651.927646528582 6077.082987780141 6838.052437618649 4329.908004709563 1.4067847453189906 1.1237453096717165 1.996537813909498 1.7977076991248044 1.5405542903172442 2.0445152284621124 2.229129957502643 1.4035131880793326 1.57926044391267 1.0 12.080120657752836 -5.253076315014876 24.965189716660497 1.742467009629398 1.2652650052966132 0.1963499427609755 0.341948141112764 862.70508931211 2575309.2198378476 0.08582994343551967 0.21906351633240995 5.5837206796199965e-06 5.253076315014876 -0.4772020043327847 GGCS(ph)PSSSASR ddPTM_PC-9_AZD4547_30min_R2 2 GGCSPSSSASR 11 0 O75712 O75712 GJB3 Gap junction beta-3 protein 1 GGCS(0.788)PS(0.202)S(0.01)SASR;GGCS(0.602)PS(0.287)S(0.11)SASR 156.01 0.00070776 6937400.0 25512.3 38934.0 41152.0 48018.0 36252.0 32527.0 36454.0 48686.0 34402.0 31032.0 True False 33624.68071119439 51518.654104133115 40606.297591760864 36948.19197070462 31219.035555069546 30493.081548034985 39698.33537924451 41162.69739298147 36220.41948692502 29945.579125405693 1.122859590405028 1.7204093428410248 1.3560030821815252 1.2338446291512173 1.0425256904977822 1.018283247097559 1.3256826729914408 1.3745834475466605 1.2095414597006668 1.0 14.870055412793176 -5.719576754568014 3.583944871607797 1.1797640775128382 1.4436028261015423 0.25560104235130565 0.17894110351876363 0.2990579941363329 7.91334566305921 0.051058575418148185 0.08982684813660201 1.907318606299024e-06 5.719576754568014 0.26383874858870415 GGCS(ph)PSSSASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGCSPSSSASR 11 0 O75712 O75712 GJB3 Gap junction beta-3 protein 1 GGCS(0.749)PS(0.223)S(0.029)SASR 100.09 0.0042935000000000004 4515800.0 13594.0 13432.0 17675.0 10542.0 31997.0 13771.0 10738.0 10341.0 13338.0 12054.0 True False 15895.195706261402 14765.44019100452 18096.439032810766 9951.365917625133 25727.417542386385 13048.824517540015 9720.818903612297 10069.559707195182 13533.043016983089 14239.294780588494 1.1162909365378326 1.0369502435705795 1.2708802866754656 0.6988664867863529 1.8067901492887768 0.9163954197597363 0.6826755856521811 0.7071670235328198 0.9504012119639386 1.0 13.797590076293245 -6.984658893877515 24.99995543458515 0.8090690750072772 1.175960823129795 0.2758838545684309 0.2720749012637027 299.120166656118 487446.3013025833 0.09265550650178893 0.08168803608915536 1.035955513489044e-07 6.984658893877515 0.3668917481225179 GGCS(ph)PSSSASR ddPTM_PC-9_Lapatinib_30min_R1 1 GGCSPSSSASR 11 0 O75712 O75712 GJB3 Gap junction beta-3 protein 1 GGCS(0.944)PS(0.045)S(0.008)S(0.002)ASR 110.98 0.0018694000000000002 4423600.0 13274.0 20239.0 8817.3 4922.3 9569.9 6034.8 6644.1 6091.6 14418.0 2998.8 True False 13084.710325846525 20192.137838980456 8092.375629762275 5284.302362311443 9007.01729714731 5776.705671805898 6988.098988169025 6374.637974479133 12794.093011729155 3517.1385843501694 3.7202714684226956 5.741069723219672 2.30084070777593 1.502443601689291 2.5608934880259935 1.6424447127303656 1.986870525734531 1.812450041873149 3.6376425622401247 1.0 11.78018646665849 -5.333059133971534 6.933508710273077 2.055591789803973 4.721113156812268 0.6383832033416164 0.8060245179161535 0.13009994032800318 10.710325105791664 0.19756901207742184 0.4166870539333766 4.644520306635547e-06 5.333059133971534 2.665521367008295 GGCSPS(ph)SSASR ddPTM_PC-9_AZD4547_30min_R2 1 GGCSPSSSASR 11 0 O75712 O75712 GJB3 Gap junction beta-3 protein 1 GGCS(0.256)PS(0.722)S(0.021)S(0.002)ASR 132.03 0.00012899 5223900.0 13411.0 23643.0 21583.0 22309.0 19560.0 15017.0 20451.0 25436.0 17496.0 13958.0 True False 17675.419033871032 31285.137385935686 21296.79531791831 17166.00472061413 16844.43163017655 14077.984616067928 22271.099381163393 21505.450661132094 18420.802841208068 13469.334668484544 1.3122711306021564 2.3226935966730737 1.5811319446793763 1.274450827981803 1.250576368080677 1.0451878257214515 1.6534669253762888 1.5966230842456086 1.3676104495576114 1.0 13.717390968717565 -5.518006705555662 10.804080311946933 1.3446631993805778 1.8511393321997072 0.3138563579614949 0.2990612849525486 0.189172282560054 358.52732771687494 0.07827255774847693 0.14500818570597243 3.033844340934687e-06 5.518006705555662 0.5064761328191294 GGCSPS(ph)SSASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGCSPSSSASR 11 0 O75712 O75712 GJB3 Gap junction beta-3 protein 1 GGCS(0.249)PS(0.625)S(0.126)SASR 117.95 0.0011119 3977900.0 12146.0 16553.0 21161.0 9436.4 29978.0 14730.0 12825.0 12388.0 15179.0 13101.0 True False 14202.077905565027 18196.27244503409 21665.558493539396 8907.709101221579 24104.02609887361 13957.532869316996 11610.123155040765 12062.828126170958 15400.964159153275 15476.107592541066 0.9176776408823833 1.1757654394832489 1.399935892406268 0.575578132159974 1.5574992584369791 0.9018761846838045 0.7501965908169591 0.7794484533039052 0.9951445521466904 1.0 13.91775504334021 -6.9719594256229875 24.999267765157576 0.8575631587879894 1.124501218842266 0.1755984672043751 0.25824765443026926 340.3231249777765 303410.4251630405 0.08708837513776026 0.07680336583708698 1.0666957736471825e-07 6.9719594256229875 0.26693806005427667 GGCSPS(ph)SSASR ddPTM_PC-9_Lapatinib_30min_R1 1 GGCSPSSSASR 11 0 O75712 O75712 GJB3 Gap junction beta-3 protein 1 GGCS(0.262)PS(0.658)S(0.078)S(0.002)ASR 117.95 0.0011119 4542800.0 14835.0 24935.0 9495.5 5259.8 11183.0 6307.0 5662.7 6135.9 14349.0 3189.6 True False 14623.45017959419 24877.26453950184 8714.816643689977 5646.623238178438 10525.237926623928 6037.264312335091 5955.886898196102 6420.996314204227 12732.86451833137 3740.918110125152 3.9090538068754905 6.6500425315831295 2.3295930002056164 1.509421770793462 2.8135440597152788 1.613845621478497 1.5920922946898852 1.7164225800145658 3.4036736821019034 1.0 11.869176669847961 -5.349499855061662 6.553375311855509 1.988708895199554 5.262496297855004 0.6815435624763907 0.8988568311156293 0.11406861292064165 7.0338729270067315 0.22035846701195744 0.46516510755364765 4.47198301033492e-06 5.349499855061662 3.2737874026554503 GGDAKS(ph)PVLQEK ddPTM_PC-9_AZD4547_30min_R2 3 GGDAKSPVLQEK 12 1 A6NFI3 A6NFI3 ZNF316 Zinc finger protein 316 1 GGDAKS(1)PVLQEK;GGDAKS(1)PVLQEK;GGDAKS(1)PVLQEK 98.943 0.015174000000000002 73799600.0 330888.0 329712.0 381418.0 489742.0 433026.0 391442.0 324907.0 403565.0 339235.0 369047.0 True False 436103.50110204425 436284.95613042405 376360.14810590603 376839.54833847383 372907.8144728435 366965.06985968264 353823.09357173915 341203.30225113075 357166.26953802153 356126.7768591648 1.2245737457548926 1.2250832694418787 1.0568150798016032 1.0581612302842933 1.0471209656338618 1.0304338053322062 0.9935312831353407 0.9580950504771064 1.0029188837975747 1.0 18.44203138918744 -4.837927968270917 0.602409502894503 0.9885946977317519 1.413914525605101 0.8988416552105386 0.027918266887986175 0.9925446287271381 0.2862782013769611 0.014675687771474417 0.2919228672827067 1.452352483612417e-05 4.837927968270917 0.425319827873349 GGDAKS(ph)PVLQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGDAKSPVLQEK 12 1 A6NFI3 A6NFI3 ZNF316 Zinc finger protein 316 1 GGDAKS(1)PVLQEK 97.223 0.01949 5672700.0 11882.0 10074.0 11699.0 14556.0 16270.0 11811.0 15078.0 16446.0 12705.0 9482.8 True False 13893.387919802692 11074.08014325339 11977.948528704572 13740.474511188713 13082.010295172242 11191.610367922805 13649.702684733302 16014.309925977363 12890.786589501444 11201.956574196498 1.240264397364819 0.9885844557514472 1.0692728943705743 1.2266137991321664 1.1678326200001894 0.9990763929314345 1.2185105873535649 1.4295993579252069 1.150762056978076 1.0 13.45146312016814 -7.493645603470245 24.21265532707983 1.2389194001638193 1.1143676617648755 0.065002536524009 0.12793270027731024 812.9397388119847 673328.0074996051 0.0521624266821036 0.035088809773268254 3.208886798404362e-08 7.493645603470245 -0.12455173839894385 GGDAKS(ph)PVLQEK ddPTM_PC-9_Lapatinib_30min_R1 1 GGDAKSPVLQEK 12 1 A6NFI3 A6NFI3 ZNF316 Zinc finger protein 316 1 GGDAKS(1)PVLQEK 96.24700000000001 0.020962 7812100.0 38487.0 30074.0 30305.0 27889.0 29746.0 30339.0 26798.0 26625.0 30471.0 26051.0 True False 37938.168322348596 30004.365500741053 27813.439880682952 29940.050094976687 27996.398762886118 29041.47169366326 28185.46931637896 27862.094699341178 27039.035106145016 30553.88063922445 1.24168084474495 0.9820148823328863 0.9103079313917534 0.9799098991222823 0.9162960048663968 0.9505002666136101 0.9224841076388518 0.911900358201059 0.8849623858068245 1.0 14.899068007495668 -4.7604350681543135 3.311093148832647 0.9327802933947199 1.2921826098824056 0.8868833695418828 0.03271995416540171 0.10028612565068554 1.6636706597397708 0.007952456733399275 0.09577950564003763 1.73606080382918e-05 4.7604350681543135 0.3594023164876857 GGDAPAAGEDA ddPTM_PC-9_AZD4547_30min_R2 1 GGDAPAAGEDA 11 0 P62851 P62851 RPS25 40S ribosomal protein S25 0 97.635 0.0020214 3065100.0 19511.0 18645.0 25241.0 35369.0 32988.0 25282.0 21916.0 31723.0 21923.0 28116.0 False True 25715.092145988947 24671.631627152685 24906.287847823576 27215.22349560274 28408.185614328428 23701.112543346164 23866.481543082333 26820.9392720197 23081.805023308458 27131.667397844358 0.9477888612194929 0.9093297240225227 0.9179785187032924 1.0030796521471814 1.0470490146354032 0.8735590111660164 0.8796540659708423 0.9885474003028156 0.8507330082168977 1.0 14.727690091846057 -9.7751183401716 14.986618017833846 1.0000047535071512 0.9374222085808515 0.09586596541247483 0.05928584801504883 0.0 0.0 0.05889216256461918 0.014283447457351248 1.6783466259642376e-10 9.7751183401716 -0.06258254492629978 GGDEYDNHCGK ddPTM_PC-9_AZD4547_30min_R2 1 GGDEYDNHCGK 11 0 F5GX30;P20645;F5H4U1;H0YGE9 F5GX30 M6PR Cation-dependent mannose-6-phosphate receptor 0 89.679 0.0076806 8762900.0 29535.0 29682.0 42013.0 54128.0 49290.0 42204.0 47643.0 48201.0 39579.0 38504.0 False True 38926.51563383647 39276.12603685417 41455.88016919346 41649.62586926364 42446.93430733139 39564.977208266 51883.134703279386 40752.642998790194 41671.06513787007 37155.98667970549 1.0476512431063507 1.0570605048232158 1.1157254556729765 1.120939842838639 1.1423982539673962 1.0648345191133435 1.3963600307677424 1.0967988375625397 1.121516849951685 1.0 15.181307060226638 -5.378694107489228 1.0013466433295386 1.152781397312812 1.029846835433384 0.08817715703697038 0.09735259732530789 1.936770255698062 2.8607528554487667 0.035101529969299015 0.20880339074206775 4.1812476643136936e-06 5.378694107489228 -0.12293456187942797 GGDLMAYDRR ddPTM_PC-9_AZD4547_30min_R2 1 GGDLMAYDRR 10 1 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 94.69200000000001 0.003926099999999999 3959800.0 10758.0 9466.8 9602.2 19269.0 18406.0 10810.0 13059.0 13977.0 10198.0 15319.0 False True 14178.820219699097 12526.757966636043 9474.868554033972 14826.829753082338 15850.644610686586 10134.048991123018 14221.225701364849 11817.175809507908 10737.045460370366 14782.6864727407 0.9591504389844746 0.8473938745663996 0.64094361816478 1.0029861473706447 1.0722438468755462 0.6855350013551477 0.962019030004378 0.7993929811945076 0.7263257243647491 1.0 13.851620855305919 -10.204169810591477 16.38672843183534 0.9999999972950789 0.8558378324937237 0.09235127231251106 0.1362517583218657 0.0 0.0 0.13238969161780897 0.03210921660489268 6.249282959499807e-11 10.204169810591477 -0.14416216480135524 GGDLMAYDRR ddPTM_PC-9_Lapatinib_30min_R1 2 GGDLMAYDRR 10 1 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 ; 132.88 8.3491e-05 21974000.0 145589.0 95977.0 111129.0 96795.0 86394.0 93079.0 84826.0 67661.0 108623.0 74734.0 False True 143512.87416224717 95754.77115330916 101992.4025903453 103913.6271986543 81312.47477713926 89098.2281477465 89217.87522319428 70804.77706862452 96388.73388910074 87651.6723232043 1.6373090251268891 1.092446597028129 1.1636104581583042 1.1855293167195502 0.9276773919077087 1.01650345950284 1.0178684885122877 0.8077972181470878 1.0996793482009064 1.0 16.419493996254488 -1.5228787453884527 0.744659432131543 0.9887039374003461 103.3546273099765 0.7531384818945799 0.10406028378358707 178.11810517143613 0.7866772084220773 0.03875455162045546 30564.13332915808 0.02999999999253167 1.5228787453884527 102.36592337257615 GGDS(ph)IGETPTPGASK ddPTM_PC-9_Lapatinib_30min_R1 2 GGDSIGETPTPGASK 15 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 GGDS(0.999)IGET(0.001)PTPGASK;GGDS(0.999)IGET(0.001)PTPGASK 74.649 0.015781 10321100.0 36838.0 53965.0 53595.0 42832.0 58449.0 59534.0 53098.0 51895.0 56852.0 51129.0 True False 36312.68336473816 53840.04735809969 49188.6259826828 45982.00816336338 55011.14473515532 56987.86960053227 55847.15462949065 54306.23115201169 50448.729081899415 59966.57952488989 0.6055486848247884 0.8978342234069345 0.8202673284419439 0.7667939130041254 0.9173633909254779 0.9503271664324081 0.9313046545586376 0.905608283518509 0.8412807514052062 1.0 15.871871063821995 -3.791982040386163 0.6227934601938979 0.9138193884774314 2.3643334239081375e-41 0.582048219481631 0.0692909707538107 8.550655335332896 0.9943384621744897 0.0318132824237402 7.384798592029573 0.0001614425317646572 3.791982040386163 -0.9138193884774314 GGDSGLDGLGGPGVQLGS(ph)PDKK ddPTM_PC-9_AZD4547_30min_R2 2 GGDSGLDGLGGPGVQLGSPDKK 22 1 Q9Y3Y4-2 Q9Y3Y4-2 1 GGDSGLDGLGGPGVQLGS(1)PDKK;GGDSGLDGLGGPGVQLGS(1)PDKK 70.407 0.00083301 10740400.0 44410.0 44333.0 38464.0 45923.0 49347.0 49879.0 48030.0 46090.0 49494.0 45490.0 True False 58531.45621461578 58662.77527093378 37953.94222806888 35336.161853277314 42496.02084122297 46760.05824497915 52304.57695356109 38967.84954283606 52110.15179599639 43897.40894607838 1.3333692721252228 1.3363607711560497 0.8646055231799629 0.8049714710196831 0.9680758354877662 1.0652122612160804 1.1915185476621115 0.8877027250219354 1.1870894671711987 1.0 15.421848166440782 -5.2474725466612835 24.459540182281483 0.9937503004304195 1.3348651244764798 0.5571641912084024 0.12077407069563643 453.23209624150184 793722.0222099134 0.03243310520562312 0.08481643430963753 5.656235110848744e-06 5.2474725466612835 0.3411148240460603 GGDSGLDGLGGPGVQLGS(ph)PDKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGDSGLDGLGGPGVQLGSPDKK 22 1 Q9Y3Y4-2 Q9Y3Y4-2 1 GGDSGLDGLGGPGVQLGS(1)PDKK;GGDSGLDGLGGPGVQLGS(1)PDKK 71.295 0.00073905 11164600.0 53269.0 71515.0 47250.0 70538.0 75067.0 53882.0 71911.0 63340.0 46543.0 52953.0 True False 62286.38958929224 78614.53657383035 48376.61919662284 66585.98454728164 60358.16022296843 51056.33306616006 65099.06948944537 61677.39211427741 47223.60332429482 62552.95972428264 0.9957384888554374 1.2567676560844285 0.7733705872568546 1.0644737649629294 0.9649129391960296 0.8162097092000642 1.0407032661026006 0.9860027788634701 0.7549379522958516 1.0 15.932790527386192 -5.256537402088301 24.997692374242117 0.9312191238838728 1.126253058998248 0.31234863822141923 0.11912070829656726 470.49060923825806 2399251.6488705687 0.02900818103390877 0.07185814683253543 5.539398357597111e-06 5.256537402088301 0.19503393511437517 GGDSGLDGLGGPGVQLGS(ph)PDKK ddPTM_PC-9_Lapatinib_30min_R1 2 GGDSGLDGLGGPGVQLGSPDKK 22 1 Q9Y3Y4-2 Q9Y3Y4-2 1 GGDSGLDGLGGPGVQLGS(1)PDKK;GGDSGLDGLGGPGVQLGS(1)PDKK 110.25 8.0664e-06 11831200.0 51336.0 59057.0 47011.0 52929.0 57379.0 48623.0 55121.0 52632.0 49698.0 52146.0 True False 50603.939226130606 58920.25714495127 43145.937047707805 56821.575225967994 54004.080031454374 46543.50763574903 57974.89567087563 55077.47486256245 44100.48789685919 61159.3666198226 0.8274111068005922 0.9633889361740773 0.7054673622751941 0.9290739647318607 0.8830058749161556 0.7610201054741407 0.9479315904505323 0.9005566588832377 0.7210749609458121 1.0 15.900285845450709 -11.019579932388712 3.4542177852432663 1.0026670771421247 0.8531540051267662 0.20646972134988684 0.08856866694315671 447635995.39955187 564623349.4161679 11296534.187410016 0.02098544832093978 9.559167412748084e-12 11.019579932388712 -0.14951307201535846 GGDSIGET(ph)PTPGASKR ddPTM_PC-9_AZD4547_30min_R2 1 GGDSIGETPTPGASKR 16 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 GGDS(0.179)IGET(0.758)PT(0.06)PGAS(0.003)KR 64.331 0.025796 11269000.0 27182.0 21647.0 37164.0 44997.0 39799.0 39101.0 36093.0 42626.0 35232.0 36255.0 True False 35825.31057927687 28643.969419843077 36671.18107747375 34623.6368467199 34273.59583074622 36656.00828879747 39305.207078594205 36039.13114803493 37094.291592446454 34985.72348516316 1.0239979914798607 0.8187330878548357 1.048175582049214 0.9896504458855392 0.9796451928536238 1.0477418969009644 1.1234641780457353 1.030109643532697 1.0602693869737323 1.0 15.094478705635867 -6.011271494643467 0.920469187709401 1.056041588466404 0.9328014451489453 0.2699081906252526 0.06442741406996888 0.7552511100673085 1.2977888584688515 0.028284436563923945 0.06259103745621282 9.743803236373544e-07 6.011271494643467 -0.1232401433174588 GGDSIGETPT(ph)PGASKR ddPTM_PC-9_AZD4547_30min_R2 1 GGDSIGETPTPGASKR 16 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 GGDSIGET(0.118)PT(0.834)PGAS(0.048)KR 100.97 0.0014462 13110000.0 40794.0 32934.0 60213.0 71279.0 64789.0 57091.0 41175.0 54769.0 51901.0 50558.0 True False 53765.64343208816 43579.27144052811 59414.53627752471 54846.72779957216 55794.16568954539 53521.09074488475 44839.4952334557 46305.70951641542 54644.38090200851 48787.97980865753 1.1020264344404629 0.8932378756292523 1.217810954881585 1.1241852606866802 1.1436047548671937 1.0970138742122566 0.9190684961605817 0.9491212732731019 1.1200377862809507 1.0 15.574238125564523 -7.228320671464101 23.001020523580433 0.9928170048103055 1.0960217013675453 0.22194728970350808 0.09090278454241345 378.92577888656706 263164.54186289926 0.035658630691283014 0.027617796367910515 5.91125002058573e-08 7.228320671464101 0.10320469655723974 GGDVS(ph)PSPYSSSSWR ddPTM_PC-9_AZD4547_30min_R2 2 GGDVSPSPYSSSSWR 15 0 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YFE7 Q14004 CDK13 Cyclin-dependent kinase 13 1 GGDVS(0.998)PS(0.002)PYSSSSWR;GGDVS(0.897)PS(0.1)PYS(0.001)S(0.001)SSWR 204.67 8.502100000000001e-13 153414000.0 90978.0 93217.0 134196.0 137779.0 129186.0 117082.0 88806.0 131540.0 108078.0 104573.0 True False 119907.11154004298 123347.5722922118 132416.47335789126 106016.18021433042 111250.7538126783 109760.84403132874 96709.56195998224 111213.51548849308 113790.78243438998 100911.93109954393 1.1882352288131457 1.2223289253134635 1.3121983883874928 1.0505812252245121 1.1024539179904873 1.0876894618442676 0.9583560725300531 1.1020848999390094 1.1276246643436225 1.0 16.622737232830907 -5.7737802343990445 24.999862456349643 1.0640397672401174 1.2390616544658988 0.6846773349176362 0.055847121202717495 126.02213214774497 255293.05148564564 0.01601424919748887 0.02394246325530037 1.683525758410987e-06 5.7737802343990445 0.17502188722578138 GGDVS(ph)PSPYSSSSWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GGDVSPSPYSSSSWR 15 0 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YFE7 Q14004 CDK13 Cyclin-dependent kinase 13 1 GGDVS(0.579)PS(0.417)PYS(0.001)S(0.001)S(0.001)S(0.001)WR;GGDVS(0.993)PS(0.007)PYSSSSWR;GGDVS(0.998)PS(0.002)PYSSSSWR 209.56 3.4662e-13 121274000.0 138505.0 146433.0 138240.0 149051.0 167323.0 165842.0 149101.0 145738.0 118969.0 127284.0 True False 161951.16090155506 160969.90049801685 141536.16587811938 140700.15569986156 134537.25928820565 157144.95357184458 134977.07388224063 141912.5319221751 120708.69655776431 150359.58162041006 1.0770923885011099 1.0705662968948202 0.9413179017445938 0.9357578292221231 0.8947701093492757 1.0451276325612857 0.8976951945968877 0.9438210082310555 0.8028001624964559 1.0 17.198057280598114 -5.268132957562382 4.533888092751421 0.9314162572626978 1.0767388392260355 0.4647978821930696 0.06069045711704022 0.1570938353437363 8.833351263146534 0.015553357555994442 0.0386184267473835 5.393454787218743e-06 5.268132957562382 0.1453225819633377 GGDVS(ph)PSPYSSSSWR ddPTM_PC-9_Lapatinib_30min_R1 2 GGDVSPSPYSSSSWR 15 0 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YFE7 Q14004 CDK13 Cyclin-dependent kinase 13 1 GGDVS(0.971)PS(0.018)PYS(0.007)S(0.002)S(0.001)S(0.001)WR;GGDVS(0.966)PS(0.033)PYSSSSWR 127.57 2.0408e-05 153869000.0 79651.0 86623.0 90686.0 76234.0 92988.0 74587.0 79408.0 77878.0 94825.0 67728.0 True False 78515.1621337954 86422.42976560134 83230.14713808316 81840.502669169 87518.62866144194 71397.08788078914 83519.35769367203 81496.49618761663 84144.80994848222 79434.69455811281 0.9884240453188285 1.087968302092185 1.0477807915179138 1.0302866162504867 1.101768303488787 0.8988149105118858 1.051421650933283 1.0259559332477253 1.0592954428360466 1.0 16.277481648056416 GGEIQPVSVK ddPTM_PC-9_Lapatinib_30min_R1 4 GGEIQPVSVK 10 0 P61604;B8ZZL8;B8ZZ54 P61604 HSPE1 10 kDa heat shock protein, mitochondrial 0 ;;; 137.46 0.00052631 25552100.0 318727.0 306964.0 275986.0 239803.0 226049.0 235004.0 223060.0 195310.0 268942.0 209804.0 False True 314181.89453262644 306253.2437178121 253295.49641676835 257438.91257935733 212753.24224943333 224953.42674108068 234608.95535903782 204384.8156142098 238650.91987518815 246068.34185374237 1.2768074599347252 1.2445861235568545 1.0293705175910912 1.0462089947855762 0.8646103787535951 0.9141908505840547 0.953430065776134 0.8306018322978405 0.9698562524432217 1.0 17.908699532929603 -5.364687408023925 1.185350512352076 0.9167417715943833 1.3245489885664417 0.8400410855330753 0.0558824445473405 0.2382635247730552 0.5255879897390076 0.017562345745737087 0.0935099431243062 4.318297829565748e-06 5.364687408023925 0.40780721697205835 GGEKT(ph)PVSGSLK ddPTM_PC-9_Lapatinib_30min_R1 1 GGEKTPVSGSLK 12 1 A0A0C4DG98;Q8NI27;Q8NI27-2;H0Y7U4;H7C477 A0A0C4DG98 THOC2 THO complex subunit 2 1 GGEKT(1)PVSGSLK 106.14 0.017585 3839300.0 31254.0 40714.0 39183.0 39390.0 42464.0 42249.0 36301.0 39057.0 42587.0 29193.0 True False 30808.312228718347 40619.72923446069 35961.52499075398 42286.87200118802 39966.35100743613 40442.108757229274 38180.48815784286 40871.73080458853 37790.403599008816 34238.97115277264 0.8998025113328652 1.1863595156880566 1.0503097429620587 1.2350508960244757 1.1672766342513097 1.181171845870559 1.115117857586414 1.1937195957851898 1.1037248587403476 1.0 15.063351730380402 -4.755526677896911 24.999821241348435 1.1450262367094135 0.8998021140546727 0.517850885021023 0.06825662009173697 142.20631961044808 601210.8166586334 0.015648392210037283 0.13770502969535864 1.7557930358075215e-05 4.755526677896911 -0.2452241226547408 GGEPGPLLTASTFS(ph)DPAGPR ddPTM_PC-9_AZD4547_30min_R2 1 GGEPGPLLTASTFSDPAGPR 20 0 E5RFT3 E5RFT3 IKBKB 1 GGEPGPLLT(0.01)AS(0.01)T(0.01)FS(0.969)DPAGPR 62.525 0.009852600000000001 21201000.0 149950.0 90208.0 96730.0 157300.0 154700.0 111440.0 80212.0 68429.0 54898.0 70681.0 True False 197630.98084624278 119365.97188641407 95447.2969977407 121036.91526077382 133222.57531637553 104471.63918323323 87350.71260876601 57854.87039198802 57799.79620351169 68206.47970362197 2.897539672257092 1.7500679173752371 1.399387527585186 1.7745662257708692 1.9532246187644986 1.5316966897748496 1.2806805597991804 0.8482312918565089 0.8474238291533223 1.0 16.057621183200958 -1.5228787453088939 0.22249193166481188 0.8198142721768943 9.9078635042872 0.7073586581149904 0.31766749173386205 32.31834405312973 0.415722246342441 0.5421070222437736 105.82904852877091 0.0299999999980274 1.5228787453088939 9.088049232110306 up GGET(ph)PEGLATSVVHYGAGAK ddPTM_PC-9_AZD4547_30min_R2 2 GGETPEGLATSVVHYGAGAK 20 0 Q9ULL5;Q9ULL5-2 Q9ULL5 PRR12 Proline-rich protein 12 1 GGET(1)PEGLATSVVHYGAGAK;GGET(0.755)PEGLAT(0.191)S(0.055)VVHYGAGAK 115.54 0.0011159 0.0 13587.7 12175.8 24523.0 36090.0 30603.0 25538.0 16874.5 29630.0 20528.0 25573.0 True False 17908.3059582827 16111.389239253724 24197.808996956453 27770.008084941706 26354.301696231727 23941.104822876925 18376.297809761953 25051.36432966441 21613.068171257386 24677.69705381541 0.7256878921574209 0.6528724785023142 0.9805537746973533 1.125307925791568 1.0679400771781944 0.9701515003878938 0.7446520544315054 1.0151419022218375 0.8758138218540047 1.0 14.590920146643661 -5.26507699848096 24.85423121733839 0.9736384590079008 0.689280170480454 0.564341862962358 0.09951349239567218 201.89593718617476 1379476.5977118644 0.02804038896954952 0.06230940142745982 5.43154024161394e-06 5.26507699848096 -0.2843582885274468 GGET(ph)PGSEQWK ddPTM_PC-9_AZD4547_30min_R2 3 GGETPGSEQWK 11 0 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9;D6RHI8 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 GGET(0.993)PGS(0.007)EQWK;GGET(1)PGSEQWK;GGET(1)PGSEQWK 139.19 0.0002376 75943000.0 179164.0 185184.0 193067.0 278550.0 333726.0 409106.0 310768.0 442249.0 364630.0 327543.0 True False 236134.42515729385 245041.10652950636 190506.8054322631 214334.60105460006 287393.90543007635 383524.5371473052 338425.74996261206 373909.5789210182 383903.5973931011 316075.8192663297 0.7470815885422853 0.7752605279906953 0.6027250229848792 0.6781113517386753 0.9092562224379285 1.213394109165125 1.070710662866146 1.1829743249228346 1.2145933791588746 1.0 18.269911143469365 -6.523123069645568 3.2326896086161914 1.1429798443519206 0.7014160770804059 0.8791073388581341 0.07597827135461403 0.07901968538254746 1.7166434878305734 0.026028180271684107 0.02767897361599684 2.9983127417276827e-07 6.523123069645568 -0.4415637672715147 GGET(ph)PGSEQWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GGETPGSEQWK 11 0 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9;D6RHI8 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 GGET(1)PGSEQWK;GGET(0.969)PGS(0.031)EQWK;GGET(0.998)PGS(0.002)EQWK 124.48 0.0012448000000000001 31773200.0 141070.0 161571.0 131087.0 147033.0 236864.0 198685.0 252197.0 211559.0 192063.0 192000.0 True False 164950.36474049554 177610.70109446035 134212.61123021584 138795.2176974177 190452.19954245133 188265.6088350473 228307.07441183765 206005.80041528953 194871.5580275018 226808.08012883653 0.727268467008745 0.7830880672045282 0.5917452815348441 0.6119500575930813 0.8397064136086618 0.8300657045732431 1.0066090867756987 0.9082824575661924 0.8591914270285546 1.0 17.791112512222043 -6.611709915809409 2.0946642261758504 0.9285901439714865 0.6821826840198928 0.7132974901175455 0.07227764809502808 0.1836501123708546 1.6424386139792784 0.02835766582748839 0.02883981552597998 2.4450631715177935e-07 6.611709915809409 -0.24640745995159374 GGET(ph)PGSEQWK ddPTM_PC-9_Lapatinib_30min_R1 3 GGETPGSEQWK 11 0 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9;D6RHI8 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 GGET(0.996)PGS(0.004)EQWK;GGET(0.993)PGS(0.007)EQWK;GGET(1)PGSEQWK 135.94 0.00018707 87603000.0 204313.0 239485.0 265006.0 246568.0 419599.0 317883.0 370908.0 302653.0 380378.0 275908.0 True False 201399.45915358444 238930.4871964141 243218.229632743 264701.4332467352 394919.01178337407 304287.88511146617 390111.8013732182 316715.3632690968 337535.82408208586 323598.33017569873 0.6223748405754566 0.7383551301599302 0.7516053296711602 0.8179938169118942 1.220398793680275 0.9403258816145685 1.2055433078452715 0.9787299059829364 1.0430703517500222 1.0 18.303844637663744 -6.066862480537354 4.566217787285706 1.0639629686956482 0.7162219953937332 0.7665362818436654 0.09118160008101163 0.09969040621284388 4.044947485559884 0.026010389468591927 0.034932414361220035 8.573092694619159e-07 6.066862480537354 -0.347740973301915 GGFDS(ph)PFYR ddPTM_PC-9_AZD4547_30min_R2 2 GGFDSPFYR 9 0 A0A2R8YEH9;A0A2R8Y6S1;A0A2R8YFV7;A0A2R8Y5N2;A0A2R8Y5S3;Q92574-2;Q92574 A0A2R8YEH9 TSC1 Hamartin 1 GGFDS(1)PFYR;GGFDS(0.966)PFY(0.034)R 106.2 0.0025853 15174500.0 48409.0 47795.0 69866.0 81218.0 71909.0 64338.0 59076.0 73308.0 56427.0 57017.0 True False 63802.05503024851 63243.799067833876 68939.53119036663 62494.44490559142 61925.67658969151 60314.93468925742 64333.649554623655 61979.93305025441 59409.61602199639 55020.85218462413 1.1595977251707916 1.149451463521819 1.2529709819658545 1.1358320059436635 1.1254946830321355 1.0962195657542497 1.1692594171160808 1.1264807902698213 1.0797654646032315 1.0 15.7476908644055 -9.864310535676925 0.20125796966217738 0.9067999093166099 1.2009683680680816 0.6447759345537654 0.037003545409229316 8.208034707609444 0.5077263303044668 0.5988432860705701 0.12775039213425576 1.3667512014198223e-10 9.864310535676925 0.2941684587514717 GGFDS(ph)PFYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGFDSPFYR 9 0 A0A2R8YEH9;A0A2R8Y6S1;A0A2R8YFV7;A0A2R8Y5N2;A0A2R8Y5S3;Q92574-2;Q92574 A0A2R8YEH9 TSC1 Hamartin 1 GGFDS(0.991)PFY(0.009)R 81.525 0.017105000000000002 5758700.0 17913.0 21582.0 17948.0 22304.0 27786.0 20324.0 21939.0 19009.0 19605.0 17042.0 True False 20945.317102123023 23724.518329530936 18375.948388169043 21054.379190543637 22341.532763469953 19258.173661642813 19860.77909539487 18510.033891700343 19891.686035983927 20131.579695602224 1.040420941566675 1.178472762110844 0.9127921735909924 1.0458384045809879 1.1097754424284199 0.9566151267230059 0.9865484674177601 0.9194526297280033 0.9880837140827701 1.0 14.297172762419406 -6.780568092285393 24.993164101820863 0.9661312787955394 1.0555001427041482 0.3056866528072194 0.06562750416506702 309.893909994652 404898.0811194645 0.023179546824711763 0.020473267754600562 1.6574174528422112e-07 6.780568092285393 0.08936886390860876 GGFDS(ph)PFYR ddPTM_PC-9_Lapatinib_30min_R1 2 GGFDSPFYR 9 0 A0A2R8YEH9;A0A2R8Y6S1;A0A2R8YFV7;A0A2R8Y5N2;A0A2R8Y5S3;Q92574-2;Q92574 A0A2R8YEH9 TSC1 Hamartin 1 GGFDS(0.998)PFY(0.002)R;GGFDS(1)PFYR 102.95 0.0030111 15609000.0 53469.0 65038.0 64751.0 57160.0 53631.0 62998.0 58500.0 52921.0 59796.0 41497.0 True False 52706.522254986325 64887.40850692282 59427.42272608814 61363.73708017022 50476.53002260286 60303.722395510675 61528.843757301656 55379.90285760887 53061.14480020506 48669.7011587232 1.0829432069676803 1.3332197848371805 1.2210352911821158 1.260820091745557 1.0371243056945672 1.239040326112672 1.2642124831759662 1.13787226013577 1.0902295172752416 1.0 15.570736295769487 -8.351001271826895 1.7664982066664423 1.0052325519095573 1.2073795497354596 0.38094181391255655 0.08347313115512468 0.34804986101592733 2.170232126578095 0.07803440620916756 0.022767508483300402 4.456549432997034e-09 8.351001271826895 0.20214699782590229 GGGAAGAGGGGSGAGGGS(ph)GGSGGR ddPTM_PC-9_AZD4547_30min_R2 1 GGGAAGAGGGGSGAGGGSGGSGGR 24 0 C9JRT7;Q6PID8 C9JRT7 KLHDC10 Kelch domain-containing protein 10 1 GGGAAGAGGGGS(0.001)GAGGGS(0.816)GGS(0.183)GGR 141.74 1.4134e-12 0.0 0.0 0.0 0.0 504.8 601.59 554.23 599.47 549.88 0.0 562.73 True False 0.0 0.0 0.0 388.4261590822544 518.0696126992794 519.5739104856715 652.8216686727307 464.9086809853479 0.0 543.0289939816818 0.0 0.0 0.0 0.7152954324485984 0.9540367428645177 0.9568069407785591 1.2021856584231534 0.856139701816789 0.0 1.0 9.084885419769124 -5.802930110468641 4.3647527305889895 0.8443287732295948 6.107071217002783e-13 0.6089976841771334 0.29885402806970185 0.1390858740552253 5.722215097004748 0.08815924192773468 0.1404502039668058 1.574236180548238e-06 5.802930110468641 -0.844328773228984 GGGAYYLISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGGAYYLISR 10 0 H0YMG9;Q8IUN5;H0YLJ2;A0A2R8Y6V7;G3XAL9;Q13621-3;Q13621;P55011-3;P55011 H0YMG9 SLC12A1;SLC12A2 Solute carrier family 12 member 1;Solute carrier family 12 member 2 0 70.256 0.030424 35644000.0 71909.0 91765.0 101910.0 102570.0 120970.0 83752.0 96697.0 86922.0 83784.0 65718.0 False True 84081.77343251069 100874.82274624269 104339.92089582738 96823.33543642655 97266.7968904111 79359.89768303033 87537.1601343452 84640.38960147162 85009.18249624463 77632.15317659827 1.083079239619192 1.2993948849617993 1.3440297174094098 1.2472066208980708 1.2529189634757107 1.0222555273264389 1.1275889763770297 1.0902749200956845 1.0950254374996535 1.0 16.244366681715995 -6.750216538523279 24.898608208570035 1.0764561584883618 1.253917795848463 0.6050158303575911 0.07166155081890763 144.8313671321146 321317.3484329813 0.0238256557894048 0.023616109676101952 1.7773929838171277e-07 6.750216538523279 0.17746163736010123 GGGDVLEPVSSDSLS(ph)TK ddPTM_PC-9_Lapatinib_30min_R1 1 GGGDVLEPVSSDSLSTK 17 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 GGGDVLEPVS(0.007)S(0.047)DS(0.186)LS(0.737)T(0.022)K 113.47 0.0021443 0.0 10094.0 10481.0 13059.0 11364.0 12424.0 11564.0 12617.0 8876.2 9234.4 12069.0 True False 9950.057708987102 10456.731888450722 11985.33942919777 12199.746469192698 11693.244746523804 11069.434677000632 13270.246524544871 9288.620656161216 8194.324629457042 14155.110569068365 0.7029304123367209 0.7387248469327177 0.8467146456197974 0.861861615963035 0.8260793647261074 0.7820097641052323 0.9374880160627574 0.6562026210136879 0.5788951339852628 1.0 13.78903539808478 -10.444839183461163 12.328750185741914 0.9999947793233724 0.7777000073598422 0.3175081729099698 0.10056445130779364 0.0 0.0 0.10291836165407311 0.024961369171485993 3.590548658098099e-11 10.444839183461163 -0.2222947719635302 GGGESLQEAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 GGGESLQEASPR 12 0 P98175-5 P98175-5 RBM10 RNA-binding protein 10 1 GGGESLQEAS(1)PR;GGGES(0.001)LQEAS(0.999)PR 81.185 0.013479 16263200.0 38067.0 32358.0 46298.0 57783.0 47289.0 43065.0 37319.0 52444.0 38574.0 44970.0 True False 50171.514157211874 42817.09070482201 45684.058269424204 44462.02208845073 40723.738617557174 40372.138742156596 40640.31870351748 44339.984843230515 40612.94288961823 43395.61398780268 1.1561425118057718 0.9866686231667726 1.0527344602674533 1.02457409868536 0.9384298290837295 0.9303276306565014 0.9365075169794892 1.0217618963910333 0.9358766741042865 1.0 15.405261615818143 -1.5228787555574204 0.6431780865348435 0.9645465560621223 15.582038339254089 0.6169389291367491 0.041599479252591776 147.93517704496853 0.979851859942464 0.01805461243872663 3074.1291819895414 0.02999999929008428 1.5228787555574204 14.617491783191966 GGGESLQEAS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGGESLQEASPR 12 0 P98175-5 P98175-5 RBM10 RNA-binding protein 10 1 GGGES(0.009)LQEAS(0.991)PR 81.789 0.012819999999999998 7049600.0 12164.0 10362.0 12777.0 15138.0 14384.0 17489.0 14089.0 12036.0 13229.0 10586.0 True False 14223.12495004882 11390.6708799277 13081.65213704233 14289.866938058172 11565.55845640797 16571.846052375084 12754.38792447324 11720.067753196141 13422.44909819083 12505.158001270114 1.1373806671298528 0.9108778056839251 1.0461005079434953 1.1427178238457114 0.9248630409334524 1.3252008531753 1.0199301698689303 0.9372186862417705 1.0733530193562968 1.0 13.610235665473674 -7.5057434746452865 24.970922384433532 0.9988863570418011 1.0762963356366095 0.09038101882778238 0.11430359352463139 1875.2067918566524 2732718.9495993215 0.048344601826414584 0.031728158431455766 3.1207323673372535e-08 7.5057434746452865 0.07740997859480847 GGGESLQEAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 GGGESLQEASPR 12 0 P98175-5 P98175-5 RBM10 RNA-binding protein 10 1 GGGESLQEAS(1)PR 148.89 0.00015469 8638300.0 23412.0 15603.0 19312.0 16924.0 21970.0 19667.0 18480.0 18385.0 20755.0 17995.0 True False 23078.14058676503 15566.872212145467 17724.241906475803 18168.64741680898 20677.76779468191 18825.8882560162 19436.803976665542 19239.234217742276 18417.353340160822 21105.411773169697 1.093470283110191 0.7375772801521403 0.8397960720675341 0.8608525439861787 0.9797377097834484 0.8919934118484555 0.9209393394245273 0.9115782446945763 0.8726365321890532 1.0 14.365325356550082 -6.20878837143582 24.96236787121699 0.9227584566935186 0.8694615346870288 0.04917357925553045 0.09018172154212176 936.4087009045102 443959.7630414742 0.025601201755983283 0.03305097837374964 6.183176284535831e-07 6.20878837143582 -0.05329692200648983 GGGFGDRDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGGFGDRDR 9 1 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 ; 78.77 0.027374000000000002 10745300.0 24282.8 18000.7 24205.1 30589.8 26029.3 30999.0 26893.8 24152.9 30936.2 26253.3 False True 28393.398432838312 19787.690533518096 24782.24138235294 28875.95267946969 20929.045517893475 29373.357869379313 24346.224569749345 23518.91196711291 31388.583399459603 31012.81546899154 0.9155375932000667 0.6380488270503208 0.7990967929735918 0.931097426750615 0.6748515154588135 0.9471361250238163 0.7850375466262375 0.7583610714296004 1.0121165371407115 1.0 14.920576885144296 -8.268474060392517 24.573309798414805 1.006058324397177 0.8040922967175947 0.4000676351591921 0.09789703884192283 454.6827323769665 1588254.751695841 0.08324724598319197 0.02337887352000669 5.389220332299464e-09 8.268474060392517 -0.20196602767958227 GGGFGDRDR ddPTM_PC-9_Lapatinib_30min_R1 2 GGGFGDRDR 9 1 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 ; 84.743 0.016815 13106500.0 25077.0 20917.6 21997.0 15090.0 16735.5 18424.4 17073.8 15815.099999999999 20392.2 17089.6 False True 24719.397381441424 20869.166582373517 20188.49157087552 16199.768938764337 15751.150793258943 17636.431361374114 17957.797821254986 16549.927281861063 18095.415696614175 20043.51458953936 1.2332865711257242 1.0411929748720345 1.0072331117723148 0.8082299571961765 0.7858477475541845 0.8799071281929021 0.8959405667620337 0.8256998645586044 0.902806522068645 1.0 14.29084788390712 -5.002625716686614 1.3330520051819925 0.864354235521702 1.2932056376226948 0.7466138890951628 0.06475058783207378 0.42485314515005174 0.8933065279761211 0.019268568068531576 0.22251467924817597 9.939723037930546e-06 5.002625716686614 0.4288514021009928 GGGGGGFNRGGSS(ph)NHFR ddPTM_PC-9_Lapatinib_30min_R1 1 GGGGGGFNRGGSSNHFR 17 1 Q9NY12-2;Q9NY12 Q9NY12-2 GAR1 H/ACA ribonucleoprotein complex subunit 1 1 GGGGGGFNRGGS(0.101)S(0.899)NHFR 83.292 0.018841 1915700.0 3604.0 3170.5 3768.1 4283.2 4186.5 4569.3 3383.8 1460.4 4748.3 3335.3 True False 3552.6062991073427 3163.158902044941 3458.3013632866323 4598.20081633634 3940.2583009756827 4373.881690558542 3558.99660693944 1528.2555154523143 4213.496452184319 3911.802160992107 0.9081763731646221 0.8086193452182929 0.8840685752905105 1.1754686528344647 1.0072744322980687 1.1181244629838956 0.9098099700514535 0.3906781203537962 1.077124117932308 1.0 11.933617692638062 GGGGGGQGAEGPPGT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 GGGGGGQGAEGPPGTPR 17 0 Q8TER5-4;Q8TER5-3;Q8TER5;G3V485;G3V3N2;G3V5C1 Q8TER5-4 ARHGEF40 Rho guanine nucleotide exchange factor 40 1 GGGGGGQGAEGPPGT(1)PR 86.411 0.012534 0.0 9244.1 5424.7 10414.0 10773.0 10136.0 10078.0 6031.1 10370.0 8315.3 11131.0 True False 12183.53151077528 7178.128189209715 10275.903555613277 8289.45129119083 8728.791360095573 9447.821066839755 6567.856216211161 8767.554778893678 8754.829781978593 10741.307078012715 1.1342689881490098 0.6682732499011438 0.9566716118420903 0.7717358074753495 0.8126377261816926 0.8795783416507378 0.6114578205901458 0.8162465438531894 0.815061865226774 1.0 13.390881940864283 -4.745539950731697 24.891801328692697 0.8076036577061759 1.134269952056096 0.42511667992731006 0.11124132578337599 798.2896054466489 1249713.0881356492 0.025948908861283326 0.6514118469699722 1.796635800117501e-05 4.745539950731697 0.32666629434992 GGGGGGQGAEGPPGT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 GGGGGGQGAEGPPGTPR 17 0 Q8TER5-4;Q8TER5-3;Q8TER5;G3V485;G3V3N2;G3V5C1 Q8TER5-4 ARHGEF40 Rho guanine nucleotide exchange factor 40 1 GGGGGGQGAEGPPGT(1)PR 117.13 0.00082178 0.0 11018.0 10512.0 9786.6 9289.3 10170.0 7983.5 7892.2 6840.3 5724.3 5786.6 True False 10860.881299546261 10487.660109855356 8981.983525368478 9972.46611019639 9571.820594989294 7642.064315447469 8300.819499168825 7158.125309742856 5079.56905444869 6786.8060998401725 1.6002934428614415 1.5453012736141583 1.3234477887293703 1.4693901613648928 1.4103571627329545 1.1260177767016857 1.2230818704787083 1.0547119225804062 0.7484476467610165 1.0 12.728517080342327 -7.114486474372498 0.6844214539307178 0.885316616067119 1.5278076085719776 0.8198081067983763 0.1088415974282958 0.3004947373558313 0.28877547412068577 0.09165502947297845 0.06842633388429693 7.682693822178403e-08 7.114486474372498 0.6424909925048586 GGGGGQDNGLEGLGNDS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 GGGGGQDNGLEGLGNDSR 18 0 P08621;P08621-4;P08621-2 P08621 SNRNP70 U1 small nuclear ribonucleoprotein 70 kDa 1 GGGGGQDNGLEGLGNDS(1)R;GGGGGQDNGLEGLGNDS(1)R 228.65 3.8322999999999997e-35 102983000.0 103370.0 125698.0 125003.0 86631.0 85410.0 111325.0 122767.0 156280.0 124322.0 82058.0 True False 136239.5097704305 166327.42034163765 123345.37854449076 66659.56138560778 73552.29578391496 104363.83015141237 133693.0251688077 132130.5169571365 130893.40711160666 79185.1743965113 1.720517897557764 2.1004868854461427 1.5576827289266544 0.8418187103032337 0.9288644792977243 1.3179718419109825 1.6883592943718755 1.6686269616015124 1.6530039632945925 1.0 16.2729427236575 -7.250128238746615 23.586023216052226 1.5582164793453304 1.4014036647234798 0.004618325055188666 0.3883402941867955 1673.6637094556697 3489932.023925391 0.16879345608216664 0.1293955255764964 5.621753012046926e-08 7.250128238746615 -0.1568128146218506 GGGGGQDNGLEGLGNDS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GGGGGQDNGLEGLGNDSR 18 0 P08621;P08621-4;P08621-2 P08621 SNRNP70 U1 small nuclear ribonucleoprotein 70 kDa 1 GGGGGQDNGLEGLGNDS(1)R;GGGGGQDNGLEGLGNDS(1)R;GGGGGQDNGLEGLGNDS(1)R;GGGGGQDNGLEGLGNDS(1)R 176.39 2.0014e-08 91046000.0 158682.0 324661.0 248629.0 181578.0 174111.0 125997.0 170386.0 103247.0 110937.0 117883.0 True False 185543.72848763957 356891.1984701999 254557.2582907338 171404.77334381835 139995.19941627112 119389.49551495798 154245.80459218548 100536.87564923883 112559.24375281573 139254.25473868573 1.332409762529822 2.5628746435066962 1.828003451445108 1.230876382667545 1.0053208045885262 0.8573489961868347 1.1076559555155552 0.7219662755576045 0.8083002129021918 1.0 17.08736188240878 -5.850437503325837 2.528494151416637 0.9145712314397234 2.0024628624105727 0.6919719296398487 0.295530664242968 0.14255317908788925 1.851733903264949 0.08508043541046666 0.14437943112337986 1.4111152868555193e-06 5.850437503325837 1.0878916309708493 GGGGGQDNGLEGLGNDS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 3 GGGGGQDNGLEGLGNDSR 18 0 P08621;P08621-4;P08621-2 P08621 SNRNP70 U1 small nuclear ribonucleoprotein 70 kDa 1 GGGGGQDNGLEGLGNDS(1)R;GGGGGQDNGLEGLGNDS(1)R;GGGGGQDNGLEGLGNDS(1)R 296.01 5.478199999999998e-121 131090000.0 197789.0 274230.0 227427.0 162557.0 202535.0 209030.7 238886.0 245015.0 192021.6 132352.6 True False 194968.49258993968 273595.0372836404 208728.82995360735 174511.98405425556 190622.28949913054 200090.944235361 251254.3482018247 256399.29137123356 170394.1053309093 155229.5705612463 1.256000978969495 1.762518805498419 1.344646056797875 1.1242186873499165 1.2280024276941481 1.2890001789730812 1.6185984879903506 1.6517425800006993 1.0976910179860337 1.0 17.244043885302133 -5.48950642866744 24.847563680395204 1.3186141432405931 1.5203405943798507 0.11680136495489069 0.2294972643370416 1304.3083131898127 971128.5152357187 0.06116727239205856 0.12718564159621173 3.239616269399353e-06 5.48950642866744 0.20172645113925758 GGGGNFGPGPGS(ph)NFR ddPTM_PC-9_AZD4547_30min_R2 2 GGGGNFGPGPGSNFR 15 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 GGGGNFGPGPGS(1)NFR;GGGGNFGPGPGS(1)NFR 108.66 0.00071195 16786700.0 73644.0 86124.0 95245.0 143238.0 123252.0 103704.0 83295.0 104981.0 100658.0 88642.0 True False 97061.26010964112 113961.89875338686 93981.9890680226 110216.69210503972 106140.58728438223 97219.37248616273 90708.09363620383 88758.59867338846 105978.57638262011 85538.67056052503 1.1347062033301416 1.3322851291305757 1.0987076190472622 1.288501345447649 1.2408491573326452 1.136554634869766 1.0604337551870302 1.0376429525004727 1.2389551496201046 1.0 16.3842891646145 -6.92659479871752 4.034984594231628 1.08823564797491 1.2220432226884703 0.3546060230619338 0.0858877803169966 0.24497787564610216 7.837868020434904 0.030159303535312525 0.026082331352192265 1.1841458609230001e-07 6.92659479871752 0.1338075747135603 GGGGNFGPGPGS(ph)NFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GGGGNFGPGPGSNFR 15 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 GGGGNFGPGPGS(1)NFR;GGGGNFGPGPGS(1)NFR;GGGGNFGPGPGS(1)NFR 87.824 0.010497 10920700.0 105531.0 104121.0 107972.0 105965.0 125135.0 108073.0 102858.0 88653.0 88499.0 74440.0 True False 123395.3139677413 114457.4447682831 110546.4619660902 100028.12459316524 100615.6950391137 102405.46162835667 93114.54561256767 86325.95268561793 89793.13045134122 87935.38273328426 1.4032498652108005 1.3016085358432177 1.2571328915618338 1.1375184991979772 1.1442003424752234 1.1645535442651274 1.0588973712094056 0.9816975829564776 1.021126282280384 1.0 16.424156161785312 -3.7286476268869357 0.2754885289060878 0.9692503404359825 2.092213523880998 0.9333352312906908 0.034121165682468146 3.904721284613771 0.15538735014157443 0.04497394994102003 1.6400005424158997 0.00018678946281058578 3.7286476268869357 1.1229631834450153 GGGGNFGPGPGS(ph)NFR ddPTM_PC-9_Lapatinib_30min_R1 3 GGGGNFGPGPGSNFR 15 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 GGGGNFGPGPGS(1)NFR;GGGGNFGPGPGS(1)NFR;GGGGNFGPGPGS(1)NFR 105.58 0.0010319 18623200.0 109861.0 122094.0 119644.0 103706.0 120056.0 110725.0 115502.0 119583.0 120017.0 96012.0 True False 108294.36199396012 121811.29884443273 109807.33215919597 111332.88519307459 112994.54211917744 105989.5498625816 121482.12840437362 125139.26273920473 106499.4216249616 112607.54627205188 0.9616972004019037 1.081732999937191 0.9751329799328831 0.9886805003645333 1.0034366777355275 0.9412295478539096 1.0788098349188906 1.111286648914959 0.9457574128084322 1.0 16.780943985731234 -7.276026590012313 24.986527121358105 1.0432373573877274 0.995668764131863 0.11482406318296234 0.05415123424294075 1649.8086069542471 2825957.2763480046 0.022205979109609558 0.015038118880972827 5.2963101583432375e-08 7.276026590012313 -0.04756859325586438 GGGGNFGPGPGSNFR ddPTM_PC-9_Lapatinib_30min_R1 2 GGGGNFGPGPGSNFR 15 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ; 152.38 6.9824e-10 14372000.0 32834.0 33090.0 30854.0 28002.0 32198.0 27167.0 29680.0 26981.0 28420.0 20958.6 False True 32365.78113898184 33013.38213804356 28317.303219884216 30061.360491933658 30304.176943703576 26005.130739370128 31216.685174644674 28234.635758983077 25219.040324132497 24581.266084420942 1.3166848700073488 1.3430301769104849 1.151987172777528 1.2229378417162116 1.2328159517751482 1.057924789148741 1.2699380523133066 1.1486241458033588 1.0259455407024687 1.0 14.585271604726046 -1.5228787453123538 0.10175104684883353 0.8930508726860784 2.158516496033827 0.6224660356092646 0.07024432551809606 85.96106574157822 0.6206531939222929 0.8590603860071716 15.194008313265986 0.029999999997788396 1.5228787453123538 1.2654656233477486 GGGGYT(ph)CQSGSGWDEFTK ddPTM_PC-9_AZD4547_30min_R2 1 GGGGYTCQSGSGWDEFTK 18 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 GGGGY(0.098)T(0.833)CQS(0.069)GSGWDEFTK 119.39 0.00021914 8642000.0 20299.0 19723.0 23776.0 24414.0 25315.0 22650.0 28294.0 29729.0 22548.0 23459.0 True False 26753.659754570715 26098.07404571371 23460.71470503756 18785.729492539947 21800.44921870753 21233.691919420562 30812.11118725914 25135.066154458073 23739.841247345677 22637.707550363866 1.1818184193364 1.1528585210163749 1.0363555873686718 0.8298423968392504 0.9630148799389858 0.9379788952649166 1.3610967947487191 1.1103185293183129 1.0486857467581383 1.0 14.466440247914646 GGGGYTCQS(ph)GSGWDEFTK ddPTM_PC-9_AZD4547_30min_R2 3 GGGGYTCQSGSGWDEFTK 18 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 GGGGYT(0.006)CQS(0.898)GS(0.096)GWDEFTK;GGGGYT(0.045)CQS(0.935)GS(0.019)GWDEFTK;GGGGYT(0.002)CQS(0.928)GS(0.064)GWDEFT(0.007)K 194.1 2.0093000000000002e-14 78853600.0 88307.0 91888.0 103169.0 107726.0 102747.0 104817.0 120113.0 135991.0 107606.0 103508.0 True False 116386.78910029432 121588.99903222329 101800.91165057303 82891.43505010898 88482.35259231848 98262.77642021641 130802.82431028676 114976.71571229781 113293.83347799703 99884.21642538342 1.1652170209218073 1.2172994231080945 1.0191891701590456 0.8298752096837184 0.8858491937854618 0.9837668045743917 1.3095444805136003 1.151099941782984 1.1342516118413064 1.0 16.6079691027739 -9.312711631035734 13.270894286017215 0.9999997601615247 1.0730853762203738 0.025424587817085342 0.14146292853142173 0.0 0.0 0.15551992942087706 0.03771912328769881 4.867302844450517e-10 9.312711631035734 0.07308561605884911 GGGGYTCQS(ph)GSGWDEFTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GGGGYTCQSGSGWDEFTK 18 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 GGGGYTCQS(0.989)GS(0.01)GWDEFTK;GGGGY(0.011)T(0.163)CQS(0.81)GS(0.016)GWDEFTK;GGGGY(0.001)T(0.009)CQS(0.965)GS(0.026)GWDEFTK;GGGGY(0.025)T(0.3)CQS(0.669)GS(0.007)GWDEFTK;GGGGYTCQS(0.939)GS(0.061)GWDEFTK 166.57 1.2606e-07 72537600.0 192124.0 178203.0 206698.0 202471.0 234340.0 160614.0 175459.0 157758.0 158889.0 144825.0 True False 224646.798578032 195893.81613740211 211626.46422653014 191127.2062898388 188422.75922376575 152191.1190952126 158838.253306846 153617.01965841796 161212.45103654428 171080.6260659311 1.3131048426924599 1.1450379896430147 1.2369984205281868 1.1171762150097704 1.10136818853557 0.889587106353943 0.9284409167735501 0.8979217763630172 0.9423185707446275 1.0 17.38431686628533 -6.394049427020898 1.4700340514006767 0.9227738672624652 1.222434542079001 0.8387056646553819 0.05645370388383564 0.14212468958012736 0.6200914681424612 0.020885276654824016 0.025740021446910268 4.035994567311628e-07 6.394049427020898 0.2996606748165358 GGGGYTCQS(ph)GSGWDEFTK ddPTM_PC-9_Lapatinib_30min_R1 4 GGGGYTCQSGSGWDEFTK 18 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 GGGGYT(0.041)CQS(0.956)GS(0.002)GWDEFT(0.001)K;GGGGYT(0.001)CQS(0.996)GS(0.003)GWDEFTK;GGGGY(0.002)T(0.021)CQS(0.977)GS(0.001)GWDEFTK;GGGGYTCQS(0.998)GS(0.002)GWDEFTK 185.2 1.3933e-10 87442100.0 178682.0 186172.0 202475.0 179770.0 172760.0 143413.0 130505.0 117566.0 156166.0 98848.0 True False 176133.96191373424 185740.93017237366 185828.28707610263 192990.88549514007 162598.5964592281 137279.56030203134 137261.91033413066 123028.54555578406 138576.94057911605 115933.74509331946 1.5192639707443019 1.6021299926338421 1.6028834997655117 1.6646653253528072 1.4025131020165555 1.1841208113438397 1.1839685694932338 1.061197026428791 1.195311515793527 1.0 16.822941030365634 -6.642349825303603 2.174715997471215 1.1195421152461045 1.5988788596004793 0.9241471898789201 0.064127988169973 0.07579773434572107 0.7324501168458939 0.023437230752281383 0.02334188740832679 2.2785059902774297e-07 6.642349825303603 0.4793367443543748 GGGPGKS(ph)PTQGST ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGGPGKSPTQGST 13 1 Q6P582 Q6P582 MZT2A Mitotic-spindle organizing protein 2A 1 GGGPGKS(0.773)PT(0.091)QGS(0.068)T(0.068) 90.861 0.026066000000000002 42402000.0 19018.0 17945.0 17981.0 23780.0 21434.0 20010.0 23978.0 23800.0 21005.0 12540.0 True False 22237.3717773782 19726.461005626574 18409.735233322244 22447.683695800206 17234.16156525642 18960.640374408205 21706.630254313255 23175.275218184448 21312.158387444128 14813.402733414618 1.5011656793220995 1.3316630460015484 1.2427755840186112 1.515363087048523 1.1634167973021683 1.27996522579101 1.4653372115070882 1.5644801964310293 1.4387078223000214 1.0 13.854615454528199 -4.756813487141977 24.514570350247656 1.3511395261408976 1.5011659724239537 0.07721009844177218 0.16398767995754987 337.6598803753269 1789119.8144358902 0.040272883388026676 0.3132948858585783 1.750598342196395e-05 4.756813487141977 0.15002644628305606 GGGPGKS(ph)PTQGST ddPTM_PC-9_Lapatinib_30min_R1 1 GGGPGKSPTQGST 13 1 Q6P582 Q6P582 MZT2A Mitotic-spindle organizing protein 2A 1 GGGPGKS(0.739)PT(0.233)QGS(0.014)T(0.014) 93.228 0.020395 52380000.0 33325.0 25618.0 30294.0 24628.0 22375.0 22150.0 22156.0 19336.0 26913.0 17685.0 True False 32849.77938894347 25558.68309496522 27803.344258221714 26439.225276599598 21058.946490942533 21202.696134171907 23303.1292698594 20234.421149538444 23881.774533546028 20741.828686218756 1.5837455745051763 1.2322290132473648 1.3404480713262643 1.2746814987516648 1.0152888064751242 1.0222192293131491 1.1234848008045895 0.9755369912481515 1.1513823055251395 1.0 14.340255473326275 -1.5228787461976823 0.36483584966259575 1.0200597540121707 7.821058343118489 0.7648101696630323 0.08810248382744695 31.11922580199316 0.43230864655505985 0.07158905015228602 147.62696778678216 0.029999999936632073 1.5228787461976823 6.800998589106318 GGGPGKSPT(ph)QGST ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGGPGKSPTQGST 13 1 Q6P582 Q6P582 MZT2A Mitotic-spindle organizing protein 2A 1 GGGPGKS(0.231)PT(0.425)QGS(0.172)T(0.172) 94.68799999999999 0.038169999999999996 11780000.0 35377.0 29806.0 35109.0 33648.0 42413.0 45310.0 40671.0 38544.0 37896.0 27817.0 True False 41365.627372400275 32764.94269900841 35946.13171162398 31762.81164828786 34102.47711426803 42933.86383630365 36818.34844745911 37532.260840743744 38450.15730781161 32860.00190074916 1.2588443390034376 0.9971071455799709 1.093917517722495 0.9666101585819968 1.0378111729047268 1.3065691221194002 1.1204609348065713 1.1421868128342398 1.170120361646571 1.0 15.00404494328848 GGGPGKSPT(ph)QGST ddPTM_PC-9_Lapatinib_30min_R1 1 GGGPGKSPTQGST 13 1 Q6P582 Q6P582 MZT2A Mitotic-spindle organizing protein 2A 1 GGGPGKS(0.104)PT(0.744)QGS(0.076)T(0.076) 104.7 0.013506 3765100.0 29726.0 20446.0 24087.0 22621.0 23273.0 26463.0 20312.0 21228.0 24473.0 20122.0 True False 29302.101788919244 20398.65854319849 22106.65983850883 24284.623801443857 21904.12789647847 25331.239178265965 21363.6559726207 22214.33037662402 21716.59302788512 23600.06088912035 1.2416112791652814 0.8643477082130026 0.9367204577298367 1.0290068282255616 0.9281386179209518 1.0733548229930072 0.9052373243015389 0.9412827568959726 0.920192245685963 1.0 14.526502961353458 -4.749786652788762 24.9954307924676 0.9565182246133395 1.2416119127755434 0.6801687218942774 0.05888146324320732 307.5859856061729 659739.2785977756 0.014439738946380376 0.22698597773773105 1.779153204599829e-05 4.749786652788762 0.28509368816220393 GGGPGKSPTQGS(ph)T ddPTM_PC-9_AZD4547_30min_R2 1 GGGPGKSPTQGST 13 1 Q6P582 Q6P582 MZT2A Mitotic-spindle organizing protein 2A 1 GGGPGKS(0.108)PT(0.021)QGS(0.436)T(0.436) 96.464 0.015719 3871200.0 17311.0 15536.0 17958.0 27443.0 23831.0 24170.0 16355.0 21011.0 18438.0 21923.0 True False 22815.537908831673 20557.708176961318 17719.865186451247 21116.440340123456 20522.477003002932 22658.64607913444 17810.563316166787 17764.232734747835 19412.595038076954 21155.48244284187 1.0784692795579094 0.9717437658301755 0.8376015642435471 0.9981545160776221 0.9700784209696376 1.071053148532719 0.8418887805696502 0.8396987770306561 0.917615331653444 1.0 14.36874396573812 -7.280452325450076 24.961702460734493 0.886442289353722 0.9799491149366788 0.23571073212597504 0.07536728756802841 1192.4857718604644 1565583.7081554334 0.032073924291058355 0.021662819031737127 5.242611484642501e-08 7.280452325450076 0.09350682558295675 GGGPLILLDLNDENS(ph)NQSFHSEGSLQK ddPTM_PC-9_AZD4547_30min_R2 1 GGGPLILLDLNDENSNQSFHSEGSLQK 27 0 I3L1Q2;Q8WUZ0;Q8WUZ0-2 I3L1Q2 BCL7C B-cell CLL/lymphoma 7 protein family member C 1 GGGPLILLDLNDENS(0.92)NQS(0.071)FHS(0.008)EGS(0.001)LQK 53.481 0.0039781999999999994 2624900.0 6073.0 2445.1 13904.0 20796.0 12330.0 14559.0 9178.5 14333.0 11450.0 13008.0 True False 8004.0876737528 3235.430758463448 13719.62387528779 16001.803494997164 10618.192331292266 13648.623428469928 9995.368718889442 12118.164189574065 12055.223624361714 12552.593879327045 0.6376441196695439 0.25774997499057956 1.0929712222971488 1.274780626922906 0.8458962691989456 1.08731498522771 0.7962791447710966 0.9653912415290958 0.9603770933922705 1.0 13.615697894336792 -5.267677642854451 24.999302357777292 1.0013819401473172 0.44769703632600033 0.6801545005145206 0.15228308526072665 247.22175766027976 990723.0605606397 0.039672044992413225 0.08598526687255302 5.3991122549800225e-06 5.267677642854451 -0.5536849038213169 GGGPQAQSHGEAR ddPTM_PC-9_AZD4547_30min_R2 1 GGGPQAQSHGEAR 13 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 0 94.68799999999999 0.0031095 702940.0 2118.5 2139.2 3351.9 5960.0 3805.9 3456.8 3301.2 3418.5 3195.9 3164.3 False True 2792.138932462588 2830.654565663984 3307.4516159074446 4586.014081082087 3277.5164796159975 3240.6457495387635 3595.0004047282064 2890.2493743151435 3364.828749440837 3053.518820137961 0.9144004333781824 0.9270139574695965 1.0831607108804426 1.5018784396668254 1.073357222493856 1.0612823894081478 1.1773303576906662 0.9465307222781614 1.1019512069975748 1.0 11.576257021815097 -10.550173087558324 14.645258362177609 0.9999978820404304 1.0920961800199427 0.025381412463623354 0.16021273008715922 0.0 0.0 0.16451068678954703 0.039899702245659203 2.8172598918481424e-11 10.550173087558324 0.0920982979795123 GGGPQAQSHGEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGGPQAQSHGEAR 13 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 0 ; 105.95 0.00078186 0.0 5448.2 6099.0 6632.5 7112.6 8157.4 8583.9 7234.6 6945.1 7073.700000000001 5057.5 False True 6370.472653145015 6704.468413113203 6790.6439538963195 6714.104081360324 6559.0160283858695 8133.74517290768 6549.286314031803 6762.798483941717 7177.139480374367 5974.384714852029 1.066297695444408 1.1222023242738657 1.1366264942756548 1.1238151544994062 1.0978563218536088 1.3614364593374086 1.0962277500728397 1.1319656846218373 1.201318599810345 1.0 12.544574426284443 -4.315218376306822 0.8513729335391615 1.1565138396136667 0.9392561793062425 0.058364903461562645 0.08775642534209083 12.725511476326833 4.126908763957159 0.030535356437759356 3.1250471995279123 4.839289723769243e-05 4.315218376306822 -0.21725766030742422 GGGPQAQSHGEAR ddPTM_PC-9_Lapatinib_30min_R1 3 GGGPQAQSHGEAR 13 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 0 ;; 111.31 0.0004865 930720.0 9339.5 8501.699999999999 9700.0 8180.2 7108.9 7196.1 6096.79 7971.2 10073.9 6881.89 False True 9206.317017345466 8482.014835992886 8902.503443082807 8781.799196347249 6690.768478635144 6888.33957792842 6412.451954377423 8341.571052296285 8939.271299130141 8071.415516957985 1.140607492948797 1.0508707943696165 1.1029668122498106 1.0880122796177143 0.8289461079754707 0.8534239828758746 0.7944643589349238 1.0334706514329122 1.1075221292162196 1.0 12.978605991648937 -6.229192613478052 19.442271344089363 0.9267422307335409 1.0929444432608382 0.41218237985028405 0.09275928477458616 48.28591020380096 29111.41414428365 0.0298897461653288 0.03857150147813564 5.89939378764008e-07 6.229192613478052 0.16620221252729728 GGGQIIPTAR ddPTM_PC-9_Lapatinib_30min_R1 2 GGGQIIPTAR 10 0 P13639;K7EJ74;K7EP67;Q15029-2;Q15029-3;Q15029 P13639;K7EJ74 EEF2;EFTUD2 Elongation factor 2;116 kDa U5 small nuclear ribonucleoprotein component 0 ; 120.31 0.0033036999999999997 18205300.0 103961.0 106597.0 106605.0 104469.0 99694.0 105843.0 99330.0 78998.0 108446.0 103918.0 False True 102478.49707588762 106350.18119580022 97840.34840720044 112151.99875836777 93830.19492594521 101316.34162208381 104472.8213745773 82668.53547637751 96231.66949299343 121880.08783796884 0.840814105845786 0.8725804442903377 0.8027590900432597 0.9201831139756489 0.7698566401649298 0.8312788694144764 0.857177109303258 0.6782776164903952 0.7895602243159423 1.0 16.895102919312578 -6.282912838085195 24.933465825620264 0.8072592533739888 0.8560250023869188 0.03369033166234969 0.08125588134903661 2161.338339644932 2509586.0687331846 0.024348475406253473 0.027631419457376627 5.212993241957037e-07 6.282912838085195 0.04876574901292996 GGGQLDLLGVSLAS(ph)LKK ddPTM_PC-9_Lapatinib_30min_R1 1 GGGQLDLLGVSLASLKK 17 1 F8WCC1;E7EXA6;A0A0D9SF58;Q8WVB6;Q8WVB6-2;H0Y7D3 F8WCC1 CHTF18 Chromosome transmission fidelity protein 18 homolog 1 GGGQLDLLGVS(0.14)LAS(0.86)LKK 84.689 0.0015414 5457700.0 33392.0 28474.0 32057.0 34231.0 25614.0 33068.0 28127.0 20169.0 23681.0 21346.0 True False 32915.82395665715 28408.07020243735 29421.397203598528 36748.461931268495 24107.434879061544 31653.75872527297 29583.278433532014 21106.125370554466 21013.79640801485 25035.627658242895 1.3147592864850635 1.1347057317767741 1.175181130076906 1.4678466397134322 0.9629251244725336 1.2643485179350429 1.1816471644876785 0.8430435880685958 0.839355685220703 1.0 14.611695004656891 -7.729134979174215 6.638887315392907 0.880462143177493 1.2131356744412491 0.5643226346707284 0.12889559644098006 0.12023698397910695 16.206504415858856 0.061046543249732625 0.03388657347084588 1.865799708230419e-08 7.729134979174215 0.3326735312637561 GGGQSVQFTDIETLKQES(ph)PNGSR ddPTM_PC-9_AZD4547_30min_R2 2 GGGQSVQFTDIETLKQESPNGSR 23 1 Q02241;A0A2U3TZL8;Q02241-2;Q02241-3 Q02241;Q02241-2 KIF23 Kinesin-like protein KIF23 1 GGGQSVQFTDIET(0.024)LKQES(0.907)PNGS(0.069)R;GGGQSVQFT(0.048)DIET(0.378)LKQES(0.564)PNGS(0.009)R 76.267 0.00016704 255420000.0 55042.0 49359.0 47995.0 62611.0 60203.0 57697.0 53765.0 55111.0 43763.0 62114.0 True False 72544.21105527767 65313.33148214688 47358.55494062408 48177.00128030714 51844.85262942325 54089.197469086415 58549.9808433939 46594.8612747936 46076.222836064764 59939.407766030155 1.2102924229490155 1.0896559361596216 0.7901071549703216 0.8037617166382948 0.8649543691154989 0.9023979295928368 0.9768194752931194 0.7773660603500424 0.7687133482519631 1.0 15.87121720885919 -5.096589504596965 3.8409941153185683 0.8569249236318428 1.1904117744478246 0.6997407504064623 0.07741779475461975 0.12091502784075953 3.145247083665888 0.020636473208761535 0.06790047963689723 8.005906162216032e-06 5.096589504596965 0.33348685081598184 GGGQSVQFTDIETLKQES(ph)PNGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GGGQSVQFTDIETLKQESPNGSR 23 1 Q02241;A0A2U3TZL8;Q02241-2;Q02241-3 Q02241;Q02241-2 KIF23 Kinesin-like protein KIF23 1 GGGQSVQFT(0.004)DIET(0.004)LKQES(0.988)PNGS(0.004)R;GGGQSVQFT(0.002)DIET(0.038)LKQES(0.822)PNGS(0.138)R;GGGQSVQFTDIET(0.001)LKQES(0.993)PNGS(0.006)R;GGGQSVQFT(0.001)DIET(0.003)LKQES(0.988)PNGS(0.008)R 128.25 2.6181e-07 119602600.0 132684.0 118701.0 122280.0 151160.0 178240.0 145308.0 160478.0 177421.0 136332.0 126328.0 True False 155144.780571545 130484.85081242007 125195.61894948268 142690.99526733186 143315.15150654584 137687.79267988543 145276.36207989312 172763.8867430881 138325.5975851954 149230.2663881024 1.0396334760139123 0.874385967207676 0.8389425414807413 0.9561799943198929 0.9603624986758842 0.9226532660727247 0.9735046756672914 1.1577000492231377 0.9269272308705309 1.0 17.187180642333644 -7.5295759899370385 24.962441473001228 1.0385086663345735 0.9292709151825508 0.2550000297681956 0.07295612771051942 202.8333571472239 756000.6660584045 0.03330131761538591 0.019285639122879002 2.9540919560490195e-08 7.5295759899370385 -0.10923775115202272 GGGQSVQFTDIETLKQES(ph)PNGSR ddPTM_PC-9_Lapatinib_30min_R1 2 GGGQSVQFTDIETLKQESPNGSR 23 1 Q02241;A0A2U3TZL8;Q02241-2;Q02241-3 Q02241;Q02241-2 KIF23 Kinesin-like protein KIF23 1 GGGQS(0.001)VQFT(0.024)DIET(0.41)LKQES(0.547)PNGS(0.017)R;GGGQSVQFTDIET(0.039)LKQES(0.957)PNGS(0.003)R 73.51899999999999 0.00024702 127975100.0 291967.0 280418.0 250574.0 224509.2 274348.0 326603.9 209672.7 223942.7 306349.8 205575.9 True False 287803.4970398092 279768.7093498309 229972.77296361144 241020.35550873596 258211.39002892078 312635.8125478766 220528.52646959963 234347.8953850202 271845.4595175909 241109.4204023318 1.193663427001568 1.1603391890826562 0.9538108157693009 0.9996306038418274 1.0709303253189006 1.2966553195067656 0.9146408551835533 0.9719566120393436 1.1274775538175605 1.0 17.879328494113132 -5.095374742058909 6.946879636433897 1.045140737269905 1.1856470710122886 0.21881117481692836 0.10277754727462997 0.3624883064451135 22.249170597621713 0.027146287443630613 0.07373212700255752 8.028330782467103e-06 5.095374742058909 0.14050633374238353 GGGS(ph)FVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGGSFVER 8 0 M0R0S1;M0R2P6;Q8TBC3;M0R1G0;M0QZE8;M0R0K4;M0QYB1;M0R0E3;M0R0S2;M0QZF4 M0R0S1 SHKBP1 SH3KBP1-binding protein 1 1 GGGS(1)FVER 81.525 0.017759999999999998 1885300.0 19935.0 17725.0 20797.0 19885.0 22322.0 17822.0 16556.0 21534.0 12613.0 10730.0 True False 23309.601765802636 19484.620859555933 21292.87935306171 18770.907918039833 17948.164339817762 16887.382946162088 14987.695824939958 20968.755317158993 12797.441263548331 12675.26406136673 1.838983523573965 1.5372161688483967 1.6798765887616367 1.4809086285825142 1.4159992449011334 1.3323101486803408 1.1824365750786485 1.654305205448951 1.0096390261843924 1.0 13.629728182482681 -1.5228787476147663 0.11590605211674612 0.8345568805861017 3.7563159290400314 0.6535732651013535 0.15836010606939457 63.43801634076676 0.5106319222201726 1.1902966430268074 29.79003682842832 0.02999999983874338 1.5228787476147663 2.9217590484539295 GGGS(ph)SQAETELLIPDEAGR ddPTM_PC-9_AZD4547_30min_R2 1 GGGSSQAETELLIPDEAGR 19 0 Q9Y2K6 Q9Y2K6 USP20 Ubiquitin carboxyl-terminal hydrolase 20 1 GGGS(0.774)S(0.225)QAET(0.001)ELLIPDEAGR 124.73 6.127e-05 0.0 1152.4 2551.6 2712.1 3018.2 3375.7 2501.6 2847.1 1217.3 1148.5 3404.5 True False 1518.839228590931 3376.35480074244 2676.1357819453387 2322.4006207251596 2907.0423238234653 2345.1745565396227 3100.486384436469 1029.1942557711936 1209.2073652907802 3285.3094912491506 0.4623123735028791 1.0277128561968973 0.8145764619965257 0.706904669685208 0.8848610249861545 0.7138367215588973 0.943742558408886 0.313271628902113 0.3680649778998482 1.0 11.681813570113327 -7.755628750014378 24.999981039991535 0.5055012219880445 0.8003742946339716 0.17004836258865574 0.22593325789888444 178.51399389725668 768058.2446638687 0.10266894437021518 0.0572251378404743 1.7553804207239915e-08 7.755628750014378 0.2948730726459271 GGGSAAAAAAAAASGGGVS(ph)PDNSIEHSDYR ddPTM_PC-9_Lapatinib_30min_R1 1 GGGSAAAAAAAAASGGGVSPDNSIEHSDYR 30 0 P40425 P40425 PBX2 Pre-B-cell leukemia transcription factor 2 1 GGGSAAAAAAAAASGGGVS(1)PDNSIEHSDYR 165.53 7.5151e-40 0.0 14599.0 8835.1 12258.0 9991.3 11458.0 10878.0 12283.0 10502.0 16308.0 6765.8 True False 14390.815582871295 8814.64286877692 11250.194557248362 10726.093531999739 10784.062967294729 10412.773297856525 12918.953638819421 10989.961259435917 14471.221309146826 7935.259515138187 1.813528033382874 1.1108197346238171 1.4177475274483757 1.3517004089831524 1.3590057069616748 1.3122158485166056 1.628044251630811 1.3849529733048098 1.8236607487807939 1.0 12.954061690467423 -7.235765111004459 24.76688476577808 1.4912439690760697 1.378832966809669 0.007046687256798023 0.2548933193868988 2449.2386851884585 2362679.0898965206 0.09034575741807681 0.06995223673438677 5.810786100179181e-08 7.235765111004459 -0.11241100226640066 GGGSCSGSAGGGGS(ph)GSLPSQR ddPTM_PC-9_AZD4547_30min_R2 2 GGGSCSGSAGGGGSGSLPSQR 21 0 O15234 O15234 CASC3 Protein CASC3 1 GGGSCS(0.003)GS(0.16)AGGGGS(0.764)GS(0.072)LPSQR;GGGSCSGS(0.019)AGGGGS(0.921)GS(0.03)LPS(0.03)QR 161.59 3.2493e-06 6701100.0 3645.71 3965.7 7767.200000000001 7924.5 9469.8 8988.6 6402.9 9441.4 7387.099999999999 7488.700000000001 True False 4804.969944521208 5247.534971509754 7664.201853001678 6097.628957304528 8155.081730646509 8426.54142105535 6972.745695939122 7982.448571788501 7777.567024936452 7226.522892382879 0.6649075933303816 0.7261493597482298 1.0605656367711966 0.8437846317115715 1.1284931705180616 1.166057528156086 0.9648825306135471 1.1046043430101642 1.076253011408073 1.0 12.819085932866537 -5.003328861720306 0.9732007762623153 1.0680285308440682 0.500608173686479 0.6967381160593957 0.0905620610510038 0.78962371010245 0.7600213240329534 0.030688831663804914 0.43667974056567926 9.923643137299127e-06 5.003328861720306 -0.5674203571575892 GGGSCSGSAGGGGS(ph)GSLPSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGGSCSGSAGGGGSGSLPSQR 21 0 O15234 O15234 CASC3 Protein CASC3 1 GGGSCSGSAGGGGS(0.969)GS(0.031)LPSQR;GGGSCSGSAGGGGS(0.998)GS(0.002)LPSQR 241.38 8.1671e-52 5828900.0 7278.2 7740.6 8435.3 8208.4 9588.7 5944.4 9836.3 5976.1 5954.9 6186.0 True False 8510.255508997474 8509.035612156766 8636.429543053397 7748.509959991854 7709.863068058889 5632.665199481871 8904.534455354968 5819.233707201347 6041.979146936021 7307.472831650947 1.1645962571543065 1.164429318888669 1.181862696176758 1.0603542617949446 1.0550655809030263 0.7708089142781399 1.2185518387131933 0.7963401084430213 0.8268219788332735 1.0 12.835156844928063 -6.22261656921692 1.6043549877810184 0.9275895357479756 1.1706153046939634 0.4162821246868349 0.12317826350789159 0.38035267501658854 1.9446464799233643 0.04403395131536394 0.061504691682004724 5.989401551831471e-07 6.22261656921692 0.2430257689459877 GGGSCSGSAGGGGS(ph)GSLPSQR ddPTM_PC-9_Lapatinib_30min_R1 2 GGGSCSGSAGGGGSGSLPSQR 21 0 O15234 O15234 CASC3 Protein CASC3 1 GGGSCSGSAGGGGS(0.853)GS(0.147)LPSQR;GGGSCSGSAGGGGS(0.582)GS(0.418)LPSQR 225.69 4.6588e-41 6650300.0 4476.6 7529.599999999999 7715.200000000001 4354.8 8073.700000000001 7151.5 7513.5 6994.200000000001 7159.4 6570.6 True False 4412.7628630921035 7512.165673817243 7080.886037533242 4675.066519186937 7598.820839504929 6845.64701596074 7902.512266162148 7319.176065582434 6353.032980175731 7706.3194552258365 0.5726161352031294 0.9748059002048075 0.9188414882971828 0.6066536102414836 0.9860505892150616 0.8883160185266581 1.0254586916719717 0.9497628677486408 0.824392632188066 1.0 12.911826276903705 -6.331281476464984 24.999997698622796 0.9442741061816392 0.7937373847191191 0.31139449117066564 0.12700652841162782 234.3147302969675 83871.99729043334 0.03898130297407364 0.044200647236912714 4.663570253899234e-07 6.331281476464984 -0.15053672146252006 GGGT(ph)PDANSLAPPGK ddPTM_PC-9_AZD4547_30min_R2 2 GGGTPDANSLAPPGK 15 0 Q9BRQ0;Q5T171 Q9BRQ0 PYGO2 Pygopus homolog 2 1 GGGT(1)PDANSLAPPGK;GGGT(0.982)PDANS(0.018)LAPPGK 195.5 2.9196e-09 78568000.0 192385.0 159285.0 229420.0 305560.0 287630.0 239730.0 197486.0 259480.0 190064.0 219160.0 True False 253559.4281434105 210770.76126205496 226377.74089963478 235117.86285494003 247697.53935519865 224739.645202768 215061.87141892457 219383.3282572167 200110.39501665375 211487.2751071128 1.1989346782920591 0.9966120238454302 1.0704083296972848 1.1117352698211225 1.1712172244393726 1.062662730364951 1.016902181514237 1.0373358309435154 0.9462053682203955 1.0 17.69021133545511 -7.2190499443013625 2.593147867781259 0.9990704353684315 1.102147562439933 0.4579108546260898 0.055775804499724156 0.2992469501122977 3.9672229701214077 0.025646260207678042 0.017714183146612637 6.038791786712865e-08 7.2190499443013625 0.10307712707150152 GGGT(ph)PDANSLAPPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GGGTPDANSLAPPGK 15 0 Q9BRQ0;Q5T171 Q9BRQ0 PYGO2 Pygopus homolog 2 1 GGGT(0.982)PDANS(0.018)LAPPGK;GGGT(0.893)PDANS(0.107)LAPPGK;GGGT(0.917)PDANS(0.083)LAPPGK;GGGT(0.874)PDANS(0.126)LAPPGK;GGGT(0.9)PDANS(0.1)LAPPGK 179.97 1.8310999999999998e-05 123653000.0 363666.0 332139.0 359919.0 409474.0 456672.0 365049.0 392777.0 342430.0 324589.0 293852.0 True False 425227.4710690924 365111.56488981965 368500.833960408 386532.49931261904 367190.39984738105 345905.18780796335 355570.31910077477 333441.57533457596 329335.5000629422 347125.04146884725 1.224997969808682 1.0518156896571422 1.061579517286076 1.1135252521022987 1.0578044104615096 0.9964858379109668 1.0243292088527858 0.9605805848049158 0.9487517773692464 1.0 18.405095918830654 -1.522878745282117 0.26696398621367073 0.9638408659414058 2.48019355108627 0.7119362755326047 0.04114417351331809 29.855630560135378 0.4155371441051884 0.050843047551666236 20.779061709159386 0.029999999999877076 1.522878745282117 1.5163526851448639 GGGT(ph)PDANSLAPPGK ddPTM_PC-9_Lapatinib_30min_R1 4 GGGTPDANSLAPPGK 15 0 Q9BRQ0;Q5T171 Q9BRQ0 PYGO2 Pygopus homolog 2 1 GGGT(1)PDANSLAPPGK;GGGT(0.921)PDANS(0.079)LAPPGK;GGGT(0.996)PDANS(0.004)LAPPGK;GGGT(0.988)PDANS(0.012)LAPPGK 207.66 1.3265e-12 110401000.0 549509.0 434165.0 498910.0 441350.0 466461.0 457261.0 412148.0 399894.0 501018.0 344343.0 True False 541672.9008923904 433159.7176175173 457891.5456482938 473808.35130044096 439024.68107761117 437705.01295745256 433487.00678434776 418474.53512481955 444588.07688656606 403862.2287417935 1.3412318913307073 1.0725432753813058 1.1337815548505863 1.1731930286636612 1.0870654639958879 1.0837978444309935 1.0733536734416793 1.036181413717618 1.1008409433871826 1.0 18.62350369857876 GGGTPDANS(ph)LAPPGK ddPTM_PC-9_AZD4547_30min_R2 2 GGGTPDANSLAPPGK 15 0 Q9BRQ0;Q5T171 Q9BRQ0 PYGO2 Pygopus homolog 2 1 GGGT(0.184)PDANS(0.816)LAPPGK;GGGT(0.309)PDANS(0.691)LAPPGK 115.12 0.00016506 80244000.0 164877.0 152920.0 193649.0 257407.0 238882.0 204075.0 177342.0 222653.0 169141.0 198254.0 True False 217304.45634535435 202348.39948641413 191081.08773199128 198065.79304850625 205717.3577034676 191314.15798921595 193125.0944430232 188247.09490694455 178081.4479518047 191313.18780382138 1.1358571713738064 1.0576813956699556 0.9987868056849897 1.035296078238 1.075291045353427 1.000005071189319 1.009470892519233 0.9839734367919221 0.9308372830754097 1.0 17.545576800935258 -1.5228787452803376 0.3052189858903875 0.9780366242507675 2.1866769619374096 0.6145409758270688 0.03324229645314393 41.50366011698232 0.5922050260130237 0.03579237588398392 27.55051173654628 0.029999999999999995 1.5228787452803376 1.2086403376866421 GGGTPDANS(ph)LAPPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGGTPDANSLAPPGK 15 0 Q9BRQ0;Q5T171 Q9BRQ0 PYGO2 Pygopus homolog 2 1 GGGT(0.249)PDANS(0.751)LAPPGK 94.71700000000001 0.015493 0.0 23235.0 20161.0 20184.0 24883.0 23635.0 22816.0 18585.0 17306.0 21525.0 16255.0 True False 27168.226587831647 22162.450840592785 20665.263108246254 23488.88618177446 19003.89141526712 21619.488794727542 16824.494256252055 16851.735837222688 21839.762403700784 19201.902825490804 1.4148715799022498 1.154179929041814 1.076209128650147 1.2232582570198522 0.989687927700539 1.1259034581732887 0.8761889073783509 0.8776075991204249 1.1373749050905613 1.0 14.228961662416516 -1.5228787452804091 0.4225954026728108 0.9812255111092387 8.500728294861803 0.5890130514753684 0.09933039679274833 56.4341384004865 0.7195896195696149 0.06767922120777109 359.40865497194056 0.02999999999999506 1.5228787452804091 7.519502783752564 GGGTPDANS(ph)LAPPGK ddPTM_PC-9_Lapatinib_30min_R1 1 GGGTPDANSLAPPGK 15 0 Q9BRQ0;Q5T171 Q9BRQ0 PYGO2 Pygopus homolog 2 1 GGGT(0.152)PDANS(0.848)LAPPGK 131.08 1.0509e-05 53493000.0 212340.0 187550.0 215100.0 177250.0 198350.0 190980.0 171140.0 181620.0 228170.0 163770.0 True False 209311.99266161257 187115.73949803723 197415.30831001198 190285.55628866603 186683.44297110412 182812.23059612417 180000.7918055486 190058.7282364074 202471.09186338188 192077.42629019226 1.0897271829610116 0.9741682982327196 1.027790262098552 0.9906711057299411 0.971917661417751 0.9517632244818287 0.9371262166622423 0.9894901858444572 1.0541118536099436 1.0 17.551328452092932 -4.75736514408234 24.996907757083964 0.9862460928648616 1.0897273337581321 0.46591252614019896 0.032409819485777716 114.1204958536399 700075.5161436616 0.008565471045763804 0.06403391566879293 1.7483760790264536e-05 4.75736514408234 0.10348124089327049 GGGTSSGGSSTNS(ph)LTGSRPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGGTSSGGSSTNSLTGSRPPK 21 1 Q5T9C2-3;Q5T9C2-2;Q5T9C2 Q5T9C2-3 FAM102A Protein FAM102A 1 GGGTSSGGSST(0.001)NS(0.498)LT(0.498)GS(0.001)RPPK;GGGT(0.01)S(0.015)S(0.016)GGS(0.016)S(0.015)T(0.013)NS(0.911)LT(0.004)GSRPPK 61.141000000000005 0.004243899999999999 21901600.0 29116.8 29627.2 35362.1 38337.6 44159.3 40419.6 34682.9 36177.2 31983.6 23919.2 True False 34045.69915698632 32568.392616656416 36205.26657551104 36189.66856417618 35506.60216518746 38299.92502136085 31397.48462954879 35227.58683291188 32451.299642973507 28255.56161571699 1.2049202779975394 1.1526365343430456 1.2813500955285233 1.2807980622139143 1.2566234799395077 1.3554827025648903 1.1111966223344902 1.2467487750559076 1.1484924661671798 1.0 14.786247244447116 -8.779742387561013 0.9132474156136666 0.9996062663961628 1.244522346294302 0.5591651238189685 0.06484113985001917 0.7337659580012896 1.1855655103770186 0.06396013593191206 0.02143767369637634 1.6605716241997107e-09 8.779742387561013 0.24491607989813924 GGGTSSGGSSTNS(ph)LTGSRPPK ddPTM_PC-9_Lapatinib_30min_R1 1 GGGTSSGGSSTNSLTGSRPPK 21 1 Q5T9C2-3;Q5T9C2-2;Q5T9C2 Q5T9C2-3 FAM102A Protein FAM102A 1 GGGT(0.003)S(0.003)S(0.003)GGS(0.002)S(0.005)T(0.004)NS(0.95)LT(0.029)GS(0.002)RPPK 66.77 0.015541999999999999 0.0 7973.3 6182.9 9076.3 8592.7 7465.4 7550.8 6442.5 7400.5 7490.0 6676.1 True False 7859.599279875858 6168.58387492624 8330.081649531188 9224.635822406915 7026.299849541112 7227.869885774505 6776.061126605401 7744.354246853501 6646.397326803397 7830.054989655923 1.0037731906428453 0.7878084998222097 1.063859916761228 1.178106135217867 0.8973500005840789 0.923093119438248 0.8653912565821152 0.9890548989865793 0.848831500619571 1.0 12.934806724110118 GGGTSSGGSSTNSLT(ph)GSRPPK ddPTM_PC-9_AZD4547_30min_R2 2 GGGTSSGGSSTNSLTGSRPPK 21 1 Q5T9C2-3;Q5T9C2-2;Q5T9C2 Q5T9C2-3 FAM102A Protein FAM102A 1 GGGTSSGGSST(0.001)NS(0.039)LT(0.952)GS(0.008)RPPK;GGGTSSGGSSTNS(0.011)LT(0.975)GS(0.014)RPPK 75.43 0.0010422 47775000.0 14557.0 11892.8 18956.1 30819.0 29060.0 26836.0 19937.4 29518.0 19574.3 26289.0 True False 19185.823195590223 15736.915023620339 18704.72972830428 23714.15569880351 25025.520612112996 25157.940677685227 21711.78997613841 24956.67135616043 20608.957536274545 25368.630111748847 0.756281403886479 0.6203297124952829 0.7373172948602239 0.9347826664010878 0.986475048194386 0.9916948832816146 0.8558518879615473 0.9837610957401429 0.8123795981687644 1.0 14.630757996533257 -5.706436797469827 4.086654634447046 0.9390029890078335 0.6869540825515695 0.7274648768002195 0.06577858014861883 0.10216479453707666 3.467794700693275 0.017661513666237433 0.030952370691471068 1.965908056797922e-06 5.706436797469827 -0.252048906456264 GGGTSSGGSSTNSLT(ph)GSRPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGGTSSGGSSTNSLTGSRPPK 21 1 Q5T9C2-3;Q5T9C2-2;Q5T9C2 Q5T9C2-3 FAM102A Protein FAM102A 1 GGGTSSGGSSTNS(0.005)LT(0.993)GS(0.002)RPPK 69.528 0.0021773000000000005 24575000.0 19410.0 16855.0 20527.0 21699.0 25690.0 22276.0 21375.0 22626.0 21867.0 18283.0 True False 22695.729635025273 18528.25300918561 21016.44152908102 20483.27537910718 20656.22891720805 21107.807345343193 19350.205258401267 22032.091474228626 22186.763506700354 21597.563171851623 1.0508467762976568 0.8578862745651655 0.9730931847196546 0.9484067816411479 0.9564147933193488 0.9773235608752966 0.8959439129512831 1.0201193208196435 1.0272808710019954 1.0 14.398580923502626 -7.795776205860189 24.955474726905965 1.0177751978056795 0.9497257809510864 0.271110932783587 0.04828913925556215 224.94568696685423 163484.0704979016 0.024464919977002075 0.01175345506154519 1.6003825013541846e-08 7.795776205860189 -0.06804941685459309 GGGTSSGGSSTNSLT(ph)GSRPPK ddPTM_PC-9_Lapatinib_30min_R1 1 GGGTSSGGSSTNSLTGSRPPK 21 1 Q5T9C2-3;Q5T9C2-2;Q5T9C2 Q5T9C2-3 FAM102A Protein FAM102A 1 GGGT(0.002)S(0.002)S(0.003)GGSSTNS(0.004)LT(0.98)GS(0.009)RPPK 67.532 0.0026306 21156000.0 27691.0 20826.0 24915.0 25042.0 28934.0 25992.0 17451.0 17643.0 27253.0 18005.0 True False 27296.12126209252 20777.778676545615 22866.58487468125 26883.672217663097 27232.15900643269 24880.382750311328 18354.527391601212 18462.75818893809 24183.480153187298 21117.140259845553 1.292605008358843 0.9839295672082438 1.0828447693820684 1.2730735263800212 1.2895760823360587 1.1782079601763888 0.8691767524271515 0.8743020106773265 1.145206209534556 1.0 14.366126853815636 -7.244746851691531 23.831945095703066 0.9616964203464581 1.1786425156378866 0.44529893221161676 0.11517036900734332 428.6857758844047 612035.8493849356 0.04631704708646918 0.035756256590192916 5.691846093271245e-08 7.244746851691531 0.2169460952914285 GGHDILVR ddPTM_PC-9_Lapatinib_30min_R1 1 GGHDILVR 8 0 H0Y8X7;Q9Y678 H0Y8X7 COPG1 Coatomer subunit gamma-1 0 83.206 0.014953999999999999 0.0 6141.1 5917.1 6338.5 5700.4 6711.7 5964.5 4901.8 5489.1 5536.0 5049.9 False True 6053.526787860186 5903.399318495543 5817.372997317564 6119.626431976953 6316.9310017099 5709.412238928596 5155.591219308395 5744.143624944741 4912.477383335597 5922.768486431217 1.0220772265079296 0.9967297104419922 0.9822050297331207 1.0332374878398047 1.06655038368994 0.9639769395019558 0.8704698201727133 0.9698409853608667 0.8294224895992222 1.0 12.532055978763024 -6.995217204364236 8.072049550586497 0.9151426592596231 1.0173876144679204 0.49573423855785836 0.048880556090646454 0.09895789305361405 55.251221099852785 0.016751654310841708 0.014265236417142857 1.0110736579713648e-07 6.995217204364236 0.10224495520829724 GGHGQQDLYR ddPTM_PC-9_AZD4547_30min_R2 2 GGHGQQDLYR 10 0 Q4KMP7;H3BSE1 Q4KMP7 TBC1D10B TBC1 domain family member 10B 0 ; 70.399 0.030112 2105600.0 5082.5 5104.9 7589.4 10640.0 9685.400000000001 8714.5 6239.9 8854.7 7017.7 7054.5 False True 6698.629277432669 6754.959093239562 7488.759597174132 8187.112386361313 8340.749392173408 8169.58093738589 6795.239011711964 7486.409575763733 7388.641295081497 6807.5241022226855 0.9840037547932498 0.9922783954645183 1.1000709633520094 1.2026563936348291 1.225225099012153 1.2000810889113838 0.9981953658442854 1.0997257539373806 1.085363956723866 1.0 12.732914469840903 -8.839096606551792 0.9164982814505404 1.001064760528159 1.1082871566811003 0.11156506842434832 0.08462671449723547 2.798869744401322 4.3153524963823005 0.09335940906061287 0.03100879474133091 1.448449617611986e-09 8.839096606551792 0.10722239615294127 GGHGQQDLYR ddPTM_PC-9_Lapatinib_30min_R1 1 GGHGQQDLYR 10 0 Q4KMP7;H3BSE1 Q4KMP7 TBC1D10B TBC1 domain family member 10B 0 86.898 0.010237999999999999 0.0 2798.9 2526.2 1982.7 2742.7 2229.6 1031.4 2877.7 607.43 3291.4 815.97 False True 2758.987172744604 2520.3507391092644 1819.6900594433282 2944.407307378987 2098.4593115622547 987.2894263108304 3026.693225305758 635.6534153322373 2920.687872021453 957.0093272883179 2.882926105393542 2.6335696708940843 1.9014339856011777 3.076675663885067 2.1927260808504667 1.0316403384576314 3.1626580211938804 0.6642081714431757 3.051890706538055 1.0 9.902389175475603 -6.52213233628639 24.999999989284543 1.8212457811028255 2.580513903588795 0.18767442442180737 0.8217131634705499 49.246207613018434 1649515.8271184685 0.24910951446749624 0.2520599558563262 3.005160443948642e-07 6.52213233628639 0.7592681224859696 GGHMDDGGYSMNFNMSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGHMDDGGYSMNFNMSSSR 19 0 P38159;P38159-2;H0Y6E7;H3BT71;Q96E39;A0A1B0GUK8 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 0 61.015 0.012516 2499500.0 4750.1 7153.8 8058.6 10191.0 14194.0 10762.0 9800.2 8347.3 7754.5 7013.1 False True 5554.198111248511 7863.981986182858 8250.74758641069 9620.031309667778 11412.787592481554 10197.621774581767 8871.854108696338 8128.192219695418 7867.894892427304 8284.519514330941 0.670430928630273 0.949238151057449 0.9959234898461121 1.1612057033635574 1.3776040448379887 1.230924950679572 1.0708954325413078 0.9811301917552249 0.9497104664690642 1.0 13.01620231108968 -4.769670055959857 1.4227933170587115 1.1178150200176749 0.4861581111033034 0.5279982558708697 0.12405243039165818 1.1000972240032592 1.984228802738509 0.040870976753383276 1.0096775246918308 1.69953433953121e-05 4.769670055959857 -0.6316569089143714 GGHMIAVS(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 1 GGHMIAVSPQK 11 0 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 GGHMIAVS(1)PQK 67.01899999999999 0.028255000000000002 14705000.0 109180.0 95373.0 101720.0 114440.0 99464.0 111920.0 128910.0 127120.0 104920.0 124030.0 True False 143896.96891492323 126200.45712933407 100371.12633733271 88057.62608037476 85655.14047361333 104921.62470735317 140382.74026823964 107476.52492699769 110465.85700157471 119687.7474517941 1.2022698394660634 1.0544141720117428 0.8386081990369029 0.7357279918384393 0.7156550465461147 0.8766279501551469 1.1729081986840861 0.897974330833533 0.9229504218555568 1.0 16.86891594421786 -5.007918900471968 3.249656296070163 0.8893222942165185 1.1939064826156311 0.38964275054750286 0.12305769242886135 0.2804049765526583 5.853277888166853 0.03568490936074814 0.16352981183632936 9.819312903398383e-06 5.007918900471968 0.3045841883991126 GGHMIAVS(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 3 GGHMIAVSPQK 11 0 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 GGHMIAVS(1)PQK;GGHMIAVS(1)PQK;GGHMIAVS(1)PQK 67.01899999999999 0.028255000000000002 29060900.0 231744.0 271115.0 279442.0 297217.0 312467.0 272277.0 259870.0 279266.0 289811.0 263370.0 True False 228439.2880633551 270487.24987475545 256467.35743731458 319075.3296668462 294088.3053937583 260632.34741868736 273324.79704632435 292241.71787065663 257169.4333348755 308893.15358153416 0.7395414414811794 0.8756660571415311 0.8302785428024014 1.0329634243014207 0.9520712970937764 0.8437621371555971 0.8848522341048866 0.9460932185844569 0.832551419003834 1.0 18.236748369347232 -4.512267004583697 1.3289736939502368 0.9168602168382527 0.5628249304848596 0.40358549637686825 0.06519687715243642 2.586634140696202 2.560754650783874 0.019109687955000617 1.4702301560055242 3.074206209269955e-05 4.512267004583697 -0.3540352863533931 GGIDNPAIT(ph)SDQELDDK ddPTM_PC-9_AZD4547_30min_R2 1 GGIDNPAITSDQELDDK 17 0 A0A0A0MSK6;Q13017-2;Q13017;H0YK04 A0A0A0MSK6 ARHGAP5 Rho GTPase-activating protein 5 1 GGIDNPAIT(0.91)S(0.09)DQELDDK 250.38 2.2146999999999996e-47 3382400.0 28164.0 23247.0 21221.0 23665.0 28085.0 25040.0 25542.0 24251.0 21816.0 24643.0 True False 37119.56615240801 30761.138130137733 20939.595674444925 18209.399870605288 24185.882532387943 23474.24484160223 27815.18851858957 20503.56518254104 22969.14922175329 23780.256070745425 1.5609405568206924 1.2935579010850191 0.8805454244121832 0.7657360718250033 1.0170572789643557 0.9871317100945919 1.1696757358642549 0.8622096045367911 0.9658915847424384 1.0 14.53747662995705 -5.030688221888403 3.116990689343709 0.9562045559934745 1.5452820982853381 0.7831349361793526 0.10351476440450785 0.12014963234000904 2.2422746433288423 0.028996739628723386 0.12886171338641125 9.31776553736514e-06 5.030688221888403 0.5890775422918636 GGIDNPAIT(ph)SDQELDDK ddPTM_PC-9_Lapatinib_30min_R1 1 GGIDNPAITSDQELDDK 17 0 A0A0A0MSK6;Q13017-2;Q13017;H0YK04 A0A0A0MSK6 ARHGAP5 Rho GTPase-activating protein 5 1 GGIDNPAIT(0.5)S(0.5)DQELDDK 187.5 5.7088e-08 2801600.0 25478.0 25257.0 21233.0 23906.0 24196.0 22538.0 21053.0 20547.0 21655.0 18754.0 True False 25114.679047907015 25198.518968285447 19487.30470175023 25664.126988078206 22772.838851166296 21574.102278644088 22143.021326879843 21501.688630511304 19215.98586274067 21995.603911865768 1.1418044782284258 1.1456161453558378 0.885963612539758 1.1667843761376977 1.0353359217784988 0.9808370056621043 1.0067021308259942 0.9775448183494514 0.8736284732047932 1.0 14.424927592013358 -1.522878745284691 0.2629633904604757 0.9485406973309704 2.313165562482967 0.34248189994836553 0.07931656909342065 59.56259810883666 0.8250483290473372 0.09558428887860755 36.56161493131142 0.029999999999699274 1.522878745284691 1.3646248651519968 GGIDNPAIT(ph)SDQELDDKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGIDNPAITSDQELDDKK 18 1 A0A0A0MSK6;Q13017-2;Q13017;H0YK04 A0A0A0MSK6 ARHGAP5 Rho GTPase-activating protein 5 1 GGIDNPAIT(0.893)S(0.107)DQELDDKK;GGIDNPAIT(0.975)S(0.025)DQELDDKK 130.73 3.4948000000000005e-05 26654700.0 52380.0 56275.0 39965.0 69628.0 68119.0 53375.0 63151.0 51248.0 52316.0 52851.0 True False 61246.899447842574 61861.61009148153 40917.9171681065 65726.96889702161 54771.57094633305 50575.92103868259 57168.88010635314 49902.79430174439 53081.022527851805 62432.46793171416 0.9810103857312142 0.9908563947711148 0.6553948373923114 1.0527690330760402 0.8772930617806065 0.8100900495235951 0.9156914983543804 0.7993083719888477 0.8502150289158751 1.0 15.93000887565736 -6.506914223614346 24.70152137626421 0.8626832004398312 0.9135253191521137 0.029757201850671433 0.11187409608539763 2349.6351050278095 3635540.5349961943 0.034601948833413616 0.03810716344170456 3.1123309848898744e-07 6.506914223614346 0.0508421187122825 GGIDNPAITS(ph)DQELDDK ddPTM_PC-9_AZD4547_30min_R2 1 GGIDNPAITSDQELDDK 17 0 A0A0A0MSK6;Q13017-2;Q13017;H0YK04 A0A0A0MSK6 ARHGAP5 Rho GTPase-activating protein 5 1 GGIDNPAIT(0.227)S(0.773)DQELDDK 235.02 2.7906e-37 3763000.0 25442.0 20047.0 25988.0 26104.0 28966.0 21118.0 28665.0 26030.0 24853.0 26461.0 True False 33532.02677352523 26526.800709548374 25643.38213974244 20086.12610277967 24944.570889554903 19797.48812160369 31216.129468536925 22007.661609894163 26166.678841594883 25534.60844410157 1.3131991762055408 1.0388567644426128 1.0042598536758058 0.7866236189503629 0.976892633547198 0.775319823875226 1.2225027666616823 0.8618758207345011 1.024753479140947 1.0 14.640166316019632 -4.682217363328611 1.9205038281568692 0.9491861112088099 1.4927548949013851 0.43231746179312314 0.12273627879732521 0.9958049293161317 3.1638424746887583 0.031839203553668045 1.0588304160128368 2.078656064422074e-05 4.682217363328611 0.5435687836925752 GGIDNPAITS(ph)DQELDDK ddPTM_PC-9_Lapatinib_30min_R1 1 GGIDNPAITSDQELDDK 17 0 A0A0A0MSK6;Q13017-2;Q13017;H0YK04 A0A0A0MSK6 ARHGAP5 Rho GTPase-activating protein 5 1 GGIDNPAIT(0.228)S(0.772)DQELDDK 215.49 2.566e-22 3708100.0 31601.0 31482.0 26617.0 24649.0 23986.0 23236.0 24982.0 27364.0 23245.0 22124.0 True False 31150.363945086356 31409.10536324832 24428.653004591262 26461.769686653544 22575.19063829039 22242.250445761558 26275.445722135202 28635.431337193335 20626.9033192984 25948.10392162306 1.200487096828996 1.2104585929715852 0.9414426995659745 1.0197958882306786 0.8700131118049841 0.8571821090644953 1.0126152493261507 1.1035654637305068 0.7949291162700176 1.0 14.66334150145392 -5.260643588578213 24.900874029204775 0.9522072362161736 1.2054728702019109 0.584952973209717 0.08608046478175006 44.34934168607411 1387659.108683004 0.02238772409848507 0.05257661275744853 5.487271027579849e-06 5.260643588578213 0.2532656339857372 GGIDNPAITS(ph)DQELDDKK ddPTM_PC-9_AZD4547_30min_R2 2 GGIDNPAITSDQELDDKK 18 1 A0A0A0MSK6;Q13017-2;Q13017;H0YK04 A0A0A0MSK6 ARHGAP5 Rho GTPase-activating protein 5 1 GGIDNPAIT(0.088)S(0.912)DQELDDKK;GGIDNPAIT(0.25)S(0.75)DQELDDKK 123.84 2.0754e-05 144207000.0 486954.0 452592.0 446029.0 453419.0 548540.0 492224.0 507659.0 480553.0 472671.0 488279.0 True False 641795.2427275844 598883.5130810553 440114.36402982846 348890.2548037176 472384.6894896231 461445.1554677644 552839.6675342049 406294.5758593736 497655.4240830279 471184.50083056034 1.3620890364523606 1.2710170050699863 0.9340595101367631 0.7404535891752089 1.0025471734680305 0.9793300812195046 1.1732976499857495 0.8622834052121732 1.0561795288380815 1.0 18.84593255829396 -5.188830159109485 4.405997651276106 0.9642348362406485 1.3363406277423309 0.6231981127825927 0.10882904524889651 0.14229571291930815 5.254665197903371 0.029177580813566775 0.08385577192701911 6.4739574531205666e-06 5.188830159109485 0.3721057915016823 GGIDNPAITS(ph)DQELDDKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGIDNPAITSDQELDDKK 18 1 A0A0A0MSK6;Q13017-2;Q13017;H0YK04 A0A0A0MSK6 ARHGAP5 Rho GTPase-activating protein 5 1 GGIDNPAIT(0.209)S(0.791)DQELDDKK;GGIDNPAIT(0.1)S(0.9)DQELDDKK 95.62200000000001 0.00040563 25759000.0 72526.0 66789.0 56013.0 89615.0 68279.0 64587.0 77635.0 75828.0 67009.0 58867.0 True False 84803.21934620524 73419.3705268763 57348.56235048543 84594.16208574988 54900.22009490264 61199.94402108463 70280.850771274 73837.59534640706 67988.87985642684 69539.12110908452 1.2195037554929153 1.055799517680198 0.8246949549523926 1.2164974295986406 0.7894868272606127 0.880079343037448 1.0106663652108279 1.061813755606425 0.9777069190991665 1.0 16.085537212798798 -4.865645127808296 3.7376524790966124 0.9711809090352934 1.2256426245906569 0.2993305537441452 0.11595487859738836 0.2930648724765335 6.866766752265878 0.028760700683931516 0.17466862171368877 1.3625576054348199e-05 4.865645127808296 0.25446171555536345 GGIDNPAITS(ph)DQELDDKK ddPTM_PC-9_Lapatinib_30min_R1 2 GGIDNPAITSDQELDDKK 18 1 A0A0A0MSK6;Q13017-2;Q13017;H0YK04 A0A0A0MSK6 ARHGAP5 Rho GTPase-activating protein 5 1 GGIDNPAIT(0.012)S(0.988)DQELDDKK;GGIDNPAIT(0.451)S(0.549)DQELDDKK 131.56 1.8646e-05 162697000.0 616060.0 627430.0 477400.0 491890.0 568070.0 536690.0 469380.0 509960.0 507800.0 509040.0 True False 607274.8714284312 625977.2243841841 438150.0148172928 528065.231496937 534657.2394685916 513737.0197854958 493682.1997060213 533654.6033005092 450606.21662894066 597026.885746837 1.017165032138837 1.04849084577009 0.7338865724098826 0.8844915431846356 0.8955329353380367 0.8604922693604465 0.8269011186798747 0.8938535534006081 0.7547502924684292 1.0 19.18743637587707 -5.238155270739192 24.92487484328387 0.8539641506945923 1.032827995150156 0.4937968925193418 0.07148791577346104 578.4676028644541 619228.4420023253 0.016909410579596672 0.04467909837389529 5.778894010854797e-06 5.238155270739192 0.1788638444555637 GGIPAS(ph)PIDPFQSR ddPTM_PC-9_AZD4547_30min_R2 3 GGIPASPIDPFQSR 14 0 Q96LD4-2;Q96LD4 Q96LD4-2 TRIM47 Tripartite motif-containing protein 47 1 GGIPAS(0.998)PIDPFQS(0.002)R;GGIPAS(1)PIDPFQSR;GGIPAS(0.997)PIDPFQS(0.003)R 185.66 5.6713e-06 55961400.0 100507.7 113175.8 121284.2 126815.0 115028.8 120114.0 101873.4 145027.0 122091.0 114191.8 True False 132467.05790996953 149757.66407660514 119675.89226231139 97579.76102221884 99059.03666161819 112603.2525920212 110939.93524507429 122616.40953892149 128544.48100628356 110193.97983927884 1.2021260880419842 1.3590367123052558 1.0860474631814026 0.8855271509799518 0.8989514382373583 1.0218639235669351 1.0067694751281644 1.1127323808229916 1.1665290716767782 1.0 16.749685882617555 -5.420952541242987 5.021592274274343 1.011340225941904 1.2766525920756757 0.5930555736185461 0.08717555438175749 0.15669017998819673 6.063218555282096 0.025261728986133943 0.053956695882714324 3.793564379556768e-06 5.420952541242987 0.26531236613377174 GGIPAS(ph)PIDPFQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GGIPASPIDPFQSR 14 0 Q96LD4-2;Q96LD4 Q96LD4-2 TRIM47 Tripartite motif-containing protein 47 1 GGIPAS(1)PIDPFQSR;GGIPAS(0.999)PIDPFQS(0.001)R;GGIPAS(0.999)PIDPFQS(0.001)R;GGIPAS(1)PIDPFQSR;GGIPAS(0.992)PIDPFQS(0.008)R 111.66 0.00037822 36070900.0 94310.6 123789.0 126181.0 117999.0 163241.0 131217.0 196927.0 134608.0 136247.0 128452.0 True False 110275.52186074243 136077.95382699984 129189.63358410735 111387.89858791979 131255.09788532372 124335.74952567335 178272.64893198502 131074.6826289654 138239.3546209997 151739.3307745272 0.7267431673637949 0.8967876234356211 0.8513918766128807 0.7340740071763827 0.8650038010274248 0.819403571183707 1.174861178193044 0.8638148195324004 0.9110317932429305 1.0 17.211235554477504 -7.099495476725559 24.593958892771106 0.9790877516877712 0.8193790986878717 0.4634562023221299 0.0903555203660504 36.34946798505778 8978.73669564605 0.03392317973194845 0.026276788924245387 7.952515482135126e-08 7.099495476725559 -0.15970865299989945 GGIPAS(ph)PIDPFQSR ddPTM_PC-9_Lapatinib_30min_R1 3 GGIPASPIDPFQSR 14 0 Q96LD4-2;Q96LD4 Q96LD4-2 TRIM47 Tripartite motif-containing protein 47 1 GGIPAS(0.995)PIDPFQS(0.005)R;GGIPAS(1)PIDPFQSR;GGIPAS(1)PIDPFQSR 162.67 0.0005514 38333000.0 31320.6 49322.6 44520.3 42676.1 80711.0 77625.0 94536.0 98792.0 84582.0 85829.0 True False 30873.962500505397 49208.39655007153 40860.01278732777 45814.642757296264 75963.73766393129 74305.159702713 99430.6115117994 103382.23697792753 75055.48447205407 100664.42829004614 0.3067018114040018 0.48883600081934137 0.40590319223387544 0.45512246516008364 0.7546234449874951 0.7381471386159992 0.9877432694030535 1.026998699878874 0.7456008616648119 1.0 16.619194443821442 -6.480695533659553 1.2153501381949758 0.9382937931594142 0.3896424216869885 0.8597941990674843 0.09407023174827936 0.15745388543759747 0.4852197964684461 0.04093398945931453 0.04816411153343482 3.3060123099863503e-07 6.480695533659553 -0.5486513714724257 down GGIVDEGALLR ddPTM_PC-9_Lapatinib_30min_R1 2 GGIVDEGALLR 11 0 A0A286YFA2;A0A286YF22;A0A2C9F2M7;O43175;A0A286YFM8;A0A286YF78;A0A286YFL2 A0A286YFA2 PHGDH D-3-phosphoglycerate dehydrogenase 0 ; 106.2 0.011351 1435000.0 34995.0 29123.0 48951.0 35840.0 38061.0 44164.0 38589.0 38069.0 42100.0 29105.0 False True 34495.96488270298 29055.56748281177 44926.43773632439 38475.793158735185 35822.32681080508 42275.20867131235 40586.94960257286 39837.8247177172 37358.25466734618 34135.760470025234 1.0105521133180566 0.8511768035261905 1.3161106451919975 1.1271403545417116 1.0494076100124041 1.2384434414002408 1.1889862432744818 1.167040785650549 1.0944022969738914 1.0 15.058996271873271 -5.248000027031032 24.998590602235254 1.154129023586129 0.9308644494260849 0.46418609560291535 0.0929768699897892 636.3663405439567 1183702.3932590247 0.022652432299390644 0.05919497092401004 5.6493693964991955e-06 5.248000027031032 -0.22326457416004408 GGKDPLS(ph)SPGGPGSR ddPTM_PC-9_Lapatinib_30min_R1 1 GGKDPLSSPGGPGSR 15 1 B7WPE2;Q32P44;G3V1D0;H0Y3M3;Q32P44-2 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 GGKDPLS(0.748)S(0.252)PGGPGSR 80.719 0.046133999999999994 4167400.0 21231.0 18703.0 18524.0 16521.0 24585.0 26912.0 29919.0 29298.0 29441.0 24473.0 True False 20928.242046711435 18659.69435260889 17001.02822470783 17736.009452440398 23138.95863596972 25761.036494936077 31468.05942520869 30659.292037607458 26125.044552525884 28703.125441777298 0.7291276376561575 0.6500927709234678 0.5923058190716364 0.6179121325451792 0.8061477027268622 0.8974993523681215 1.0963286729537487 1.0681516930899437 0.9101811788935352 1.0 14.808920217978333 -6.688045134305909 1.9170669380705612 1.0212867813334696 0.6445763657759684 0.8778909701313846 0.06169034396824146 0.10761625750245249 0.8138830407517207 0.025197637760098264 0.024330700880009815 2.0509490216829514e-07 6.688045134305909 -0.3767104155575012 GGKDPLSS(ph)PGGPGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGKDPLSSPGGPGSR 15 1 B7WPE2;Q32P44;G3V1D0;H0Y3M3;Q32P44-2 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 GGKDPLS(0.138)S(0.862)PGGPGSR 115.58 0.0037199 0.0 12966.0 11521.0 12978.0 14798.0 20621.0 19356.0 23218.0 16989.0 20527.0 14704.0 True False 15160.887709826788 12664.72874036355 13287.444739339076 13968.916035763314 16580.463079087098 18340.937285709417 21018.62295623677 16543.05675133342 20827.1685417313 17369.718803200052 0.8728343781267013 0.7291268721074693 0.7649775387780664 0.8042108334643735 0.9545613988887633 1.0559144620309244 1.21007272451437 0.9524078621402706 1.1990504151336216 1.0 14.084286778127833 -6.4782003661610625 2.1014110066873743 1.0906565165991633 0.7819034712192307 0.7419339181444082 0.08087440873094703 0.1513922298570435 1.3335222405347373 0.027753186357047176 0.030881677285330946 3.3250611283576416e-07 6.4782003661610625 -0.30875304537993264 GGKDPLSS(ph)PGGPGSR ddPTM_PC-9_Lapatinib_30min_R1 1 GGKDPLSSPGGPGSR 15 1 B7WPE2;Q32P44;G3V1D0;H0Y3M3;Q32P44-2 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 GGKDPLS(0.124)S(0.876)PGGPGSR 142.4 0.00043496 3576200.0 18958.0 20530.0 20979.0 16195.0 24417.0 30548.0 29888.0 28254.0 32811.0 23126.0 True False 18687.655443528587 20482.464046359437 19254.187601281883 17386.034324936278 22980.840065669 29241.533250866083 31435.454396892834 29566.783986298073 29115.479664852613 27123.298286541984 0.6889890472059961 0.7551612576750081 0.7098763357565333 0.6410000045445382 0.8472730647611398 1.078096511049142 1.1589834711396605 1.090088073874426 1.0734490826766119 1.0 14.727245005380107 -6.62621991835572 3.0320229092608395 1.0931757534281183 0.7050763688061051 0.9381758014777597 0.04627309014667134 0.05652634928542771 1.0436103121740363 0.016400725833558144 0.01642766259591249 2.3647219446330782e-07 6.62621991835572 -0.3880993846220132 GGKT(ph)NT(ph)GS(ph)AIK ddPTM_PC-9_Lapatinib_30min_R1 1 GGKTNTGSAIK 11 1 A0A1B0GUV4;A0A0D9SGF2;A0A0D9SET0 A0A1B0GUV4 MAGI2 3 GGKT(1)NT(1)GS(1)AIK 84.352 0.044348 7799800.0 22123.0 43744.0 28106.0 27594.0 40450.0 27419.0 25977.0 38738.0 31267.0 38712.0 True False 21807.521963138683 43642.71345562338 25795.233172297463 29623.354810885543 38070.81052775981 26246.353286810812 27321.961953562823 40537.90890002176 27745.381203893427 45403.317619502406 0.48030679488874056 0.9612230062429892 0.5681354254433921 0.6524491240737266 0.8385028346784726 0.5780712657776583 0.601761355470355 0.8928402377937515 0.6110870891949041 1.0 15.470510098614792 -14.522859272194733 0.3727475601693464 5.092013783997092 0.6880023911432317 0.28047466195984605 0.14972143271578328 726.8063333504184 5.570153311642371 2397.44945303843 0.09812738215002546 3.0001345183256566e-15 14.522859272194733 -4.40401139285386 GGLLTSEEDSGFST(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 1 GGLLTSEEDSGFSTSPK 17 0 Q9UQR1 Q9UQR1 ZNF148 Zinc finger protein 148 1 GGLLTSEEDSGFST(0.919)S(0.08)PK 207.72 5.0367e-17 27447000.0 50392.0 56009.0 38194.0 32962.0 45421.0 48138.0 58686.0 45338.0 42544.0 44070.0 True False 66415.60778128619 74112.81393430912 37687.52260448371 25363.12015782345 39115.07817353009 45127.92325020161 63908.94031015372 38332.053863595145 44792.788984702594 42527.12271386402 1.5617235200263015 1.7427187452338042 0.8861996815081361 0.5963986872207314 0.9197678017558055 1.061156277932006 1.502780725142243 0.9013554507673932 1.053275794981069 1.0 15.376095628426564 -5.26069482233851 24.99760096323035 0.9908664983782959 1.6522211812325722 0.6003196416911623 0.21609769308937934 46.1347939682802 1548846.7464195455 0.061547444265548444 0.14457252519000452 5.48662373188947e-06 5.26069482233851 0.6613546828542763 GGLLTSEEDSGFST(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 2 GGLLTSEEDSGFSTSPK 17 0 Q9UQR1 Q9UQR1 ZNF148 Zinc finger protein 148 1 GGLLTSEEDSGFS(0.001)T(0.987)S(0.012)PK;GGLLTSEEDSGFS(0.001)T(0.92)S(0.08)PK 273.84 3.784099999999999e-82 55038000.0 140551.0 187093.0 121015.0 153811.0 167681.0 155230.0 186724.0 176107.0 124066.0 141837.0 True False 138546.71696610327 186659.79765345933 111065.61383140893 165122.77403845437 157818.3332535302 148591.17475880389 196391.65507245122 184289.57413021155 110092.38060710151 166353.33646407753 0.8328460367010502 1.1220682531592434 0.6676488502855639 0.9926027186963642 0.9486935255284743 0.8932262972128051 1.1805693786902807 1.1078201258079798 0.6617984523014058 1.0 17.343891276346845 GGLLTSEEDSGFST(ph)SPKDNSLPK ddPTM_PC-9_AZD4547_30min_R2 2 GGLLTSEEDSGFSTSPKDNSLPK 23 1 Q9UQR1 Q9UQR1 ZNF148 Zinc finger protein 148 1 GGLLT(0.001)S(0.002)EEDS(0.024)GFS(0.065)T(0.487)S(0.421)PKDNSLPK;GGLLTSEEDS(0.007)GFS(0.127)T(0.671)S(0.183)PKDNS(0.012)LPK 89.604 1.6062e-05 36571000.0 68920.0 53876.0 61899.0 86791.0 86518.0 75551.0 65560.0 64828.0 59592.0 72334.0 True False 90835.12637494513 71290.36339739765 61078.17881591188 66782.67585758306 74506.4691093872 70826.78402667312 71394.71299345128 54810.32219924009 62741.911460520765 69801.60867675614 1.3013328503013877 1.0213283726387423 0.875025375113609 0.9567498102636368 1.0674033238176326 1.014686987439852 1.0228233180709723 0.7852300718893298 0.8988605370267599 1.0 16.09097266531439 -4.783989498543718 3.528490548380001 0.9534461059500956 1.341687889272856 0.6388367048937924 0.07837074704129568 0.19368115897231036 4.0107550239308996 0.02158841980598443 0.20101872524602374 1.644411485420673e-05 4.783989498543718 0.3882417833227605 GGLLTSEEDSGFST(ph)SPKDNSLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GGLLTSEEDSGFSTSPKDNSLPK 23 1 Q9UQR1 Q9UQR1 ZNF148 Zinc finger protein 148 1 GGLLTS(0.001)EEDS(0.004)GFS(0.084)T(0.589)S(0.323)PKDNSLPK;GGLLTS(0.001)EEDS(0.003)GFS(0.044)T(0.483)S(0.469)PKDNSLPK;GGLLTSEEDS(0.002)GFS(0.352)T(0.526)S(0.12)PKDNSLPK 102.92 2.5733e-06 35405900.0 125929.0 77000.0 78749.0 128706.0 120972.0 119549.0 121196.0 136005.0 119485.0 106892.0 True False 147246.29248887664 84644.05112472796 80626.67481724576 121495.0200904818 97268.40500476834 113279.63998601344 109715.43749694494 132435.01285920918 121232.24208158803 126270.67344339349 1.1661163156375056 0.6703381617955294 0.6385225691648052 0.9621792359011011 0.7703166725278715 0.8971175720924316 0.8688908873692657 1.0488184567937633 0.9600981667048433 1.0 16.94616008434138 -7.647068460104962 4.745173332534867 1.0026444163547636 0.8378851133314503 0.18441561030579345 0.14259807508061192 0.3409146003555417 12.596823683696403 0.07014495089356541 0.03891065804492336 2.25388389267088e-08 7.647068460104962 -0.16475930302331332 GGLLTSEEDSGFST(ph)SPKDNSLPK ddPTM_PC-9_Lapatinib_30min_R1 2 GGLLTSEEDSGFSTSPKDNSLPK 23 1 Q9UQR1 Q9UQR1 ZNF148 Zinc finger protein 148 1 GGLLT(0.004)S(0.01)EEDS(0.016)GFS(0.223)T(0.339)S(0.339)PKDNS(0.069)LPK;GGLLT(0.002)S(0.011)EEDS(0.056)GFS(0.257)T(0.462)S(0.211)PKDNSLPK 80.786 0.0001207 19750200.0 87364.0 53207.0 56890.0 63976.0 52424.0 52614.0 39821.7 43561.0 52589.0 43021.6 True False 86118.17333940437 53083.802460528364 52212.72380175063 68681.00845767967 49340.523389549584 50363.82186922442 41883.472776925475 45585.0030872489 46665.87303327955 50457.82623732139 1.706735699123452 1.0520429915243685 1.0347794920093332 1.3611567041086563 0.9778566987306048 0.9981369715045822 0.8300689090317203 0.9034278027128272 0.9248490573849355 1.0 15.622790434769968 -2.177639060831609 1.04830781345332 0.9838683088708148 199.99999995068296 0.6977893047314667 0.1364312784760711 286.3638470782992 1.4737711451279627 0.046107857575101996 135596.48240742914 0.0066429493201259696 2.177639060831609 199.01613164181214 GGLLTSEEDSGFSTS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 GGLLTSEEDSGFSTSPK 17 0 Q9UQR1 Q9UQR1 ZNF148 Zinc finger protein 148 1 GGLLTSEEDSGFST(0.281)S(0.718)PK 264.03 3.4138e-69 24462000.0 63521.0 80650.0 56141.0 44353.0 57252.0 56230.0 69427.0 58913.0 61228.0 52229.0 True False 83719.35668112167 106718.53530329105 55396.53365812224 34128.10109701908 49303.54804145541 52713.92921099415 75605.86850207954 49809.34953606204 64464.38708056058 50400.478607270335 1.6610825729151915 2.11741114870875 1.0991271350770708 0.6771384328103593 0.9782357113240451 1.0459013618055226 1.5001021932988805 0.9882713599643671 1.279043153198579 1.0 15.621149813295613 -5.273438235116487 23.689475366689823 1.0676108853997597 1.889246819182817 0.678038497323652 0.22553436729546092 185.24496933950894 365732.31556029397 0.060982036720278916 0.12874828556547416 5.3279699273724e-06 5.273438235116487 0.8216359337830572 GGLLTSEEDSGFSTS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GGLLTSEEDSGFSTSPK 17 0 Q9UQR1 Q9UQR1 ZNF148 Zinc finger protein 148 1 GGLLTSEEDSGFS(0.001)T(0.206)S(0.794)PK;GGLLTSEEDSGFST(0.231)S(0.768)PK;GGLLTSEEDSGFST(0.078)S(0.922)PK;GGLLTSEEDSGFST(0.067)S(0.932)PK 231.17 1.27e-29 45446700.0 195003.0 249122.0 150277.0 178455.0 181497.0 128057.0 195582.0 117860.0 118746.0 138723.0 True False 228013.15641519023 273853.1857700592 153860.17360869623 168456.7449089159 145933.96573711574 121341.46548853548 177055.05706894214 114766.29988299235 120482.43560463897 163872.38176933618 1.3914068615670543 1.6711369104009852 0.9389024065401518 1.027975202960268 0.8905342325623226 0.7404631834748918 1.080444765355041 0.7003394876174762 0.7352211172119771 1.0 17.322213204762896 -5.308124038872256 6.576849625141578 0.8830048826725556 1.5306903094242066 0.7753397733524289 0.13824923982631404 0.08589303025911021 9.628632986195 0.0363939852633791 0.07797501541361053 4.918990243077101e-06 5.308124038872256 0.647685426751651 GGLLTSEEDSGFSTS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 GGLLTSEEDSGFSTSPK 17 0 Q9UQR1 Q9UQR1 ZNF148 Zinc finger protein 148 1 GGLLTSEEDS(0.01)GFS(0.066)T(0.433)S(0.49)PK 93.478 0.0018694000000000002 2314600.0 13266.0 17536.0 15393.0 14249.0 17025.0 16254.0 16940.0 16642.0 12909.0 14428.0 True False 13076.824407313552 17495.396469408635 14127.44695869832 15296.918993270581 16023.622972437835 15558.854309924604 17817.070311943407 17415.248074607938 11455.05248220361 16921.86057589845 0.772776985642978 1.033893193419113 0.8348636898013349 0.9039738227755967 0.9469185081964356 0.919452931321562 1.0529025595045969 1.029156811480424 0.6769381198258345 1.0 14.046600582525564 -6.191397709591487 4.68970018361924 0.9439314944163242 0.8921930715185052 0.04351006917282829 0.11482637381684556 0.8728611883757218 37.120267969292634 0.03392909794070666 0.04396093572532589 6.435796309778854e-07 6.191397709591487 -0.051738422897818936 GGLLTSEEDSGFSTS(ph)PKDNSLPK ddPTM_PC-9_AZD4547_30min_R2 1 GGLLTSEEDSGFSTSPKDNSLPK 23 1 Q9UQR1 Q9UQR1 ZNF148 Zinc finger protein 148 1 GGLLTSEEDS(0.007)GFS(0.158)T(0.131)S(0.695)PKDNS(0.008)LPK 93.77600000000001 5.2213e-06 16688000.0 58518.0 39244.0 47382.0 66046.0 64454.0 47861.0 53284.0 49760.0 44166.0 60699.0 True False 77125.50674998623 51928.855541752724 46753.683721151174 50820.11510052806 55505.67465702446 44868.244103990626 58026.17277521438 42070.73537104625 46500.52459332393 58573.946485337714 1.316720340318752 0.8865521047783865 0.7981993108976292 0.8676232036584628 0.9476171230995796 0.7660102621772649 0.9906481679485186 0.7182499711126249 0.7938772676852837 1.0 15.83797148046804 -4.762749192209224 4.9846283909760905 0.8540687640755521 1.346120275564778 0.6937553414317841 0.09046764006798583 0.09143122292349133 5.951634530058787 0.021501510255244285 0.1580073857760267 1.7268348620620475e-05 4.762749192209224 0.492051511489226 GGLLTSEEDSGFSTS(ph)PKDNSLPK ddPTM_PC-9_Lapatinib_30min_R1 2 GGLLTSEEDSGFSTSPKDNSLPK 23 1 Q9UQR1 Q9UQR1 ZNF148 Zinc finger protein 148 1 GGLLTSEEDS(0.001)GFS(0.007)T(0.033)S(0.958)PKDNSLPK;GGLLT(0.001)S(0.003)EEDS(0.076)GFS(0.279)T(0.238)S(0.404)PKDNSLPK 116.09 1.4099e-08 30930000.0 180173.0 121201.0 120911.0 125109.0 105868.0 108554.0 99356.0 100809.0 115927.0 99451.0 True False 177603.69998031802 120920.36653106751 110970.16430995747 134309.93321138946 99641.05238449617 103911.39847173357 104500.16752735822 105492.95416134762 102870.08049457113 116640.97283987216 1.5226527664865854 1.0366885973856734 0.951382362545109 1.151481592971397 0.8542542981126029 0.890865327524196 0.8959130310994476 0.9044245053251669 0.8819377787237245 1.0 16.83171513201099 -2.118247954027415 1.0508025037424806 0.9250827374086641 199.99999994401185 0.8193773853487324 0.08131554069039279 221.40782276539048 0.9765913052613908 0.025775716000785064 105314.76518975313 0.0076164403644007235 2.118247954027415 199.07491720660317 GGLNTPLHESDFSGVT(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 1 GGLNTPLHESDFSGVTPQR 19 0 Q99459 Q99459 CDC5L Cell division cycle 5-like protein 1 GGLNTPLHESDFS(0.013)GVT(0.987)PQR 128.04 1.1765e-05 0.0 1324.4 3582.9 12312.0 30828.0 16229.0 13822.0 5691.9 19028.0 8982.0 16766.0 True False 1745.531650768681 4741.002357571752 12148.734835482102 23721.08088785211 13975.883482931247 12957.708154977088 6198.468073328633 16087.659819941086 9456.770182883567 16179.027443173225 0.10788854008064692 0.2930338287776518 0.7508940125204057 1.466162349447109 0.8638271695885157 0.8008953690504197 0.38311747075650643 0.9943527122657368 0.5845079511793443 1.0 13.981837266360484 -5.239580442032357 3.6096689046911323 0.8632005771425856 0.16208062522718045 0.49482639718472665 0.26851529159660414 0.1972738967959386 5.564393816500045 0.07441661665587826 0.21054074250474977 5.759961200134876e-06 5.239580442032357 -0.7011199519154051 GGLRPGS(ph)LDAEIDLLSSTLAELNGGR ddPTM_PC-9_AZD4547_30min_R2 1 GGLRPGSLDAEIDLLSSTLAELNGGR 26 1 Q15654 Q15654 TRIP6 Thyroid receptor-interacting protein 6 1 GGLRPGS(1)LDAEIDLLSSTLAELNGGR 56.588 0.0020106 7286100.0 1181.5 678.8 1214.7 1630.3 1207.1 2855.5 894.68 2653.9 1377.8 1242.0 True False 1557.1924232733302 898.2088253425175 1198.5922843291194 1254.4595228839141 1039.515001062684 2676.9451335940576 974.3047867751827 2243.8007355550576 1450.6276951655516 1198.5179580353788 1.2992649904269218 0.7494329303291118 1.0000620151690196 1.0466756167260398 0.8673336883217554 2.2335461188934786 0.8129246460122064 1.8721461122143848 1.2103512387444184 1.0 10.227035810482247 GGLS(ph)PANDTGAK ddPTM_PC-9_AZD4547_30min_R2 2 GGLSPANDTGAK 12 0 P30419;B7Z8J4;K7EN42 P30419 NMT1 Glycylpeptide N-tetradecanoyltransferase 1 1 GGLS(0.999)PANDT(0.001)GAK;GGLS(1)PANDTGAK 201.08 3.6889e-06 379220000.0 608210.0 581660.0 672590.0 728210.0 668590.0 721060.0 657600.0 814050.0 630010.0 630800.0 True False 801608.1284461054 769670.2200187511 663671.0171375012 560332.4352323468 575767.8192034616 675972.0042126885 716125.1260599995 688257.2775080424 663311.0424090932 608715.8840005766 1.3168838690027451 1.2644161919356487 1.0902804322695685 0.9205155474993585 0.9458728354834852 1.1104885250736258 1.1764521756086148 1.1306708032402693 1.0896890648716258 1.0 19.215409486827 -5.2460003020895405 3.67922804716226 1.0581778433749114 1.3023700984397464 0.6018776012468914 0.07648344696639325 0.1734998611879654 5.186675860782485 0.023352640053486463 0.06481231039765738 5.675442106321072e-06 5.2460003020895405 0.244192255064835 GGLS(ph)PANDTGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GGLSPANDTGAK 12 0 P30419;B7Z8J4;K7EN42 P30419 NMT1 Glycylpeptide N-tetradecanoyltransferase 1 1 GGLS(1)PANDTGAK;GGLS(0.999)PANDT(0.001)GAK;GGLS(1)PANDTGAK 175.6 5.7271e-05 434466000.0 1465688.0 1520280.0 1535630.0 1739580.0 1647200.0 1483180.0 1617950.0 1390223.0 1331894.0 1213274.0 True False 1713800.029742447 1671203.3512194997 1572245.2431092095 1642116.972394451 1324442.9845241387 1405399.4298108348 1464686.0630563912 1353731.1193130275 1351370.430054104 1433230.971928298 1.1957598344645495 1.1660390990372116 1.0969936276173817 1.1457448272870587 0.9240959834563206 0.9805812582461723 1.021946979757054 0.9445310252343279 0.942883915099841 1.0 20.45083969476788 -6.251844983990536 24.876069486998027 0.9694588375100993 1.1483317930834285 0.8651628956161889 0.03521669580390244 232.60668202141636 603095.491955883 0.010961277110919836 0.01396640632791809 5.599574356654565e-07 6.251844983990536 0.17887295557332916 GGLS(ph)PANDTGAK ddPTM_PC-9_Lapatinib_30min_R1 2 GGLSPANDTGAK 12 0 P30419;B7Z8J4;K7EN42 P30419 NMT1 Glycylpeptide N-tetradecanoyltransferase 1 1 GGLS(1)PANDTGAK;GGLS(0.999)PANDT(0.001)GAK 170.26 0.0005785 408210000.0 662010.0 931150.0 866900.0 820540.0 875470.0 793980.0 813310.0 838990.0 829920.0 740400.0 True False 652569.6160022342 928993.9793846842 795626.8283307736 880885.2488411992 823976.5758402445 760023.3262577789 855419.2122436076 877972.538283576 736445.6701549636 868377.1534790138 0.7514817880546703 1.0698047221334863 0.9162226633245961 1.014403989455588 0.9488694774374412 0.8752226186661721 0.9850779800188291 1.0110497895598933 0.8480712179086151 1.0 19.727962244383292 -4.741412850649334 24.88875257996475 0.9611566759510127 0.7514810122942365 0.4923554160006234 0.0644616709299618 1160.4093444720281 1442065.5189654254 0.015234415819035629 0.6070405428328574 1.8137906105318997e-05 4.741412850649334 -0.20967566365677626 GGLS(ph)PANDTGAKK ddPTM_PC-9_AZD4547_30min_R2 2 GGLSPANDTGAKK 13 1 P30419;B7Z8J4;K7EN42 P30419 NMT1 Glycylpeptide N-tetradecanoyltransferase 1 1 GGLS(1)PANDTGAKK;GGLS(0.999)PANDT(0.001)GAKK 161.82 0.00046327 17057100.0 24183.0 16094.5 26526.0 34383.0 31775.0 25979.0 22821.0 24754.0 20125.8 26298.0 True False 31872.690962352015 21296.732379898564 26174.247908219488 26456.530562054584 27363.58972642432 24354.529023162337 24852.02478986501 20928.838090331155 21189.608700364974 25377.31502448821 1.2559520552744055 0.8392035311595404 1.0314033570124446 1.042526781754688 1.0782696948049637 0.959696839467102 0.9793007954499396 0.8247065566288462 0.8349822934348158 1.0 14.631251816507575 -7.37871600375466 1.9279386069149396 0.8764387987117437 1.0328184995222924 0.2698652818435737 0.10738221183331585 0.4498119608422501 3.2614156162957597 0.05712196561074449 0.03275577578979626 4.181036859423063e-08 7.37871600375466 0.15637970081054875 GGLS(ph)PANDTGAKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGLSPANDTGAKK 13 1 P30419;B7Z8J4;K7EN42 P30419 NMT1 Glycylpeptide N-tetradecanoyltransferase 1 1 GGLS(1)PANDTGAKK 153.0 0.00021003 4486300.0 10457.0 5000.7 8523.4 12573.0 12379.0 15367.0 10692.0 11681.0 10767.0 8502.4 True False 12227.163564835622 5497.13644752504 8726.630181174502 11868.575572215981 9953.423813395035 14561.127467942579 9679.176356623462 11374.386127042546 10924.44700583723 10043.817815038637 1.21738205431483 0.5473154281327327 0.8688558814864297 1.181679694990597 0.9910000357126894 1.449760214302191 0.9636949350207054 1.1324763487855827 1.0876787300422777 1.0 13.294020144441943 -5.723805013638486 7.853766083655604 1.12311446857378 0.8430843521455008 0.2232900777012754 0.19941007872290428 0.281973098910814 49.36061718749851 0.05157866878141819 0.08856714941357213 1.888839195965585e-06 5.723805013638486 -0.28003011642827913 GGLVS(ph)DAYGEDDFSR ddPTM_PC-9_AZD4547_30min_R2 1 GGLVSDAYGEDDFSR 15 0 J3KS14;F5H478;J3KRU5;X6R3T8;J3QLH3;J3QQJ0;Q9UHR5-2;Q9UHR5 J3KS14 SAP30BP SAP30-binding protein 1 GGLVS(1)DAYGEDDFSR 130.06 1.34e-05 2687300.0 15981.0 18333.0 26962.0 29090.0 28417.0 22188.0 23332.0 27843.0 21633.0 24118.0 True False 21062.62557455021 24258.78372864522 26604.466263342165 22383.749936019783 24471.79006312508 20800.580852454892 25408.50279992686 23540.504118489567 22776.476215355182 23273.636160947874 0.9049993490012685 1.0423289064452412 1.143116016739287 0.9617641945257664 1.0514811649495346 0.893740054566864 1.0917289685296876 1.0114665347389715 0.9786384928356445 1.0 14.506409007634833 GGLVS(ph)DAYGEDDFSR ddPTM_PC-9_Lapatinib_30min_R1 2 GGLVSDAYGEDDFSR 15 0 J3KS14;F5H478;J3KRU5;X6R3T8;J3QLH3;J3QQJ0;Q9UHR5-2;Q9UHR5 J3KS14 SAP30BP SAP30-binding protein 1 GGLVS(1)DAYGEDDFSR;GGLVS(1)DAYGEDDFSR 167.61 0.00016574 3700400.0 13683.5 13732.2 17236.9 14558.3 16950.9 19369.1 13458.099999999999 13986.900000000001 14796.3 14089.2 True False 13488.37078075342 13700.403934603846 15819.748618358148 15628.965947065124 15953.881388751633 18540.728744577384 14154.89456701097 14636.782435688849 13129.784882053546 16524.49944732108 0.816265014486725 0.8290964563422785 0.9573511541932253 0.9458057109015101 0.9654683604554235 1.1220145459584963 0.8566005047315206 0.8857625298938623 0.7945647566457525 1.0 14.012318950477278 -5.253407492493771 20.624393411794024 0.9413697939783181 0.8226804650532282 0.24532357680085515 0.0829686044429851 81.9749813008652 210477.18189373965 0.022455186871614605 0.05655741482070247 5.57946435648949e-06 5.253407492493771 -0.11868932892508988 GGNFGFGDS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 GGNFGFGDSR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 GGNFGFGDS(1)R 67.252 0.044081 7103400.0 55005.0 69416.0 64657.0 81741.0 62280.0 60270.0 47813.0 50101.0 52394.0 42892.0 True False 72495.44582492542 91853.36449613469 63799.60593386672 62896.87533586095 53633.49703105292 56501.30737233896 52068.26437394574 42359.04165644668 55163.43987552905 41390.364135308744 1.7515053887405152 2.219196820686524 1.541412047627805 1.5196018843962213 1.295796694508903 1.3650836022517514 1.2579803406350811 1.0234034549193924 1.3327604390044725 1.0 15.3370073204079 -5.75684289802383 0.8264638843172628 1.1694199858192083 2.0628789981704823 0.7497028400331114 0.1702573229678478 0.3986474888276107 0.48611301455319605 0.07397271275542419 0.2541539747573344 1.7504797938384602e-06 5.75684289802383 0.893459012351274 GGNFGFGDSR ddPTM_PC-9_AZD4547_30min_R2 4 GGNFGFGDSR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;;; 131.62 0.00017896 64612400.0 149044.0 156432.0 196886.0 281998.0 225908.0 195423.0 174197.0 233477.0 180576.0 199887.0 False True 196436.89169221348 206995.58480551076 194275.16299697311 216987.71792566887 194544.57365592633 183203.16891695053 189700.195535696 197398.4944177199 190120.87870678958 192889.01697086723 1.0183933475169409 1.0731330796132064 1.007186236146951 1.124935578672379 1.0085829494652314 0.949785383294376 0.9834681026154389 1.023378611792779 0.9856490623077013 1.0 17.557411473641537 -6.508230940974524 24.95266918797076 0.9884476924765405 1.0552989140907874 0.4651603618456688 0.03424208064317787 585.4798885152887 997371.590910004 0.01047412604361718 0.011451130203632372 3.1029091425160594e-07 6.508230940974524 0.06685122161424684 GGNFGFGDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GGNFGFGDSR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;;; 131.12 0.00087768 99054000.0 338217.0 333497.0 388931.0 377818.0 410610.0 339482.0 376413.0 352495.0 318961.0 286851.0 False True 395470.4580097548 366604.3781551099 398204.5900690316 356650.08236248343 330153.91808854736 321678.9662960946 340756.43564587575 343242.37974932534 323625.2012100724 338854.81558873376 1.1670793502599506 1.0818921888955995 1.1751480921915842 1.0525159034344305 0.9743226387824259 0.9493120696461183 1.0056119021175427 1.012948212505018 0.9550556353988916 1.0 18.370307748697343 -5.9971504174032475 3.7050255650464967 0.983906178028417 1.134949115979923 0.8413579003757119 0.030729814853381072 0.08391271548646652 2.529945944508657 0.008953622633415715 0.013004054510826115 1.0065829795932335e-06 5.9971504174032475 0.15104293795150603 GGNFGFGDSR ddPTM_PC-9_Lapatinib_30min_R1 1 GGNFGFGDSR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 99.01299999999999 0.020906 66658000.0 73739.0 69676.0 74585.0 51539.0 55758.0 57240.0 55234.0 54263.0 57684.0 52830.0 False True 72687.46833792348 69514.66950288079 68452.90920642593 55329.34998906392 52478.424064445775 54791.97863295712 58093.74625796241 56784.257076820715 51187.020480551 61961.595108449925 1.1731051825037802 1.1218992890872306 1.1047635085348337 0.8929620015789177 0.8469508245001444 0.8842893495084497 0.9375766740072183 0.9164427897221264 0.8261088241992408 1.0 15.919086664177721 -5.720589747981979 4.438531600761995 0.8949295181365112 1.1388537282610218 0.8372984443105018 0.047114298674429345 0.07281625605158264 3.1204553878395043 0.012913475936752628 0.022292349064194496 1.9028749633299316e-06 5.720589747981979 0.2439242101245106 GGNIGDGGGAADR ddPTM_PC-9_Lapatinib_30min_R1 1 GGNIGDGGGAADR 13 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 87.641 0.032244999999999996 11076000.0 38454.0 36847.0 50468.0 34121.0 31544.0 39286.0 37656.0 35565.0 53651.0 33815.0 False True 37905.63890840008 36761.68303537294 46318.71585211373 36630.37216431927 29688.64393789011 37605.82936013893 39605.643427776944 37217.479736415764 47608.25940992377 39659.877694344745 0.9557679224463466 0.9269237620623053 1.167898605464396 0.9236128373018794 0.7485813286338885 0.9482084047248913 0.9986325155365889 0.9384164021696605 1.2004136718937086 1.0 15.275392608048273 -8.237430672906752 24.324109911643397 1.1002068531825415 0.9512660794843991 0.24146235565081764 0.10577766728426778 713.3169335020314 722690.7856765363 0.07444245170977633 0.02810058311693699 5.7885438438613164e-09 8.237430672906752 -0.1489407736981424 GGNLPPVS(ph)PNDSGAK ddPTM_PC-9_AZD4547_30min_R2 3 GGNLPPVSPNDSGAK 15 0 Q9UK61-3;Q9UK61;Q9UK61-2;Q9UK61-4;A0A087X0F1 Q9UK61-3 FAM208A Protein FAM208A 1 GGNLPPVS(1)PNDSGAK;GGNLPPVS(0.999)PNDS(0.001)GAK;GGNLPPVS(0.995)PNDS(0.005)GAK 164.53 0.00010409 26989200.0 183595.0 181329.0 211428.0 259798.0 242636.0 223382.0 189129.0 239184.0 199585.0 224246.0 True False 241974.3909867683 239940.0531681396 208624.32657539865 199905.5849390879 208950.17960222502 209413.88822710834 205961.11460857853 202223.6087015342 210134.6556391468 216395.21579516988 1.1182058258432594 1.1088047962911354 0.964089366804085 0.9237985424239215 0.9655951904223613 0.9677380687811983 0.951782200229104 0.9345105341559404 0.9710688605890944 1.0 17.723309077922792 -5.262573366485403 5.163872774535044 0.9558695758705048 1.1159175345417363 0.9058761206038302 0.019809491695099924 0.040473846103398915 3.6427392952433437 0.004960215750869327 0.012131614066307968 5.462942551907115e-06 5.262573366485403 0.16004795867123145 GGNLPPVS(ph)PNDSGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GGNLPPVSPNDSGAK 15 0 Q9UK61-3;Q9UK61;Q9UK61-2;Q9UK61-4;A0A087X0F1 Q9UK61-3 FAM208A Protein FAM208A 1 GGNLPPVS(1)PNDSGAK;GGNLPPVS(0.991)PNDS(0.009)GAK;GGNLPPVS(0.995)PNDS(0.005)GAK;GGNLPPVS(1)PNDSGAK 195.5 1.1940999999999998e-09 20533500.0 220538.0 232640.0 208822.0 265009.0 293752.0 275290.0 276375.0 243630.6 241794.9 200315.6 True False 257870.72757595102 255734.9617358025 213801.10844184473 250161.40490077063 236193.40431637605 260853.3077796521 250194.7592182759 237235.55489795873 245330.6929814909 236631.23258258283 1.089757783710803 1.0807320696626663 0.9035202416368662 1.0571783030097934 0.9981497443873814 1.1023621224160083 1.0573192578496986 1.0025538569392567 1.0367637877044487 1.0 17.8522809797216 -9.841382579495646 0.0034850912902371733 8.519848034902844e-09 2.040953080894097 0.03532508003126589 0.05512142269545209 189733.53324946924 168.9474568455696 50223.34547181654 48718.044909696764 1.4408455200040596e-10 9.841382579495646 2.0409530723742493 GGNLPPVS(ph)PNDSGAK ddPTM_PC-9_Lapatinib_30min_R1 3 GGNLPPVSPNDSGAK 15 0 Q9UK61-3;Q9UK61;Q9UK61-2;Q9UK61-4;A0A087X0F1 Q9UK61-3 FAM208A Protein FAM208A 1 GGNLPPVS(1)PNDSGAK;GGNLPPVS(0.996)PNDS(0.004)GAK;GGNLPPVS(0.985)PNDS(0.015)GAK 115.04 0.00016629 32928200.0 270253.0 211258.0 232163.0 209098.0 227577.0 240602.0 217178.0 231833.0 254669.0 198579.0 True False 266399.14266166947 210768.84508065242 213075.45431509629 224475.76445047962 214191.36829359658 230312.01333065578 228422.414179885 242604.8075279766 225985.4954365413 232903.1155601145 1.1438195750237155 0.9049636136200634 0.9148673421678616 0.9638160653653441 0.9196586648421702 0.9888747635546767 0.9807615223632636 1.0416554838458483 0.9702982928891404 1.0 17.829370413140005 -7.219904118731412 2.5872486026804165 1.0035456301282555 0.9626644438118871 0.03057046506132377 0.06597894522431424 0.8709648414423077 11.494171924250695 0.029591243115843102 0.020418460507503223 6.026926307201693e-08 7.219904118731412 -0.04088118631636839 GGPAS(ph)PGGLQGLETR ddPTM_PC-9_AZD4547_30min_R2 2 GGPASPGGLQGLETR 15 0 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3 C9JWC4 HJURP Holliday junction recognition protein 1 GGPAS(1)PGGLQGLETR;GGPAS(1)PGGLQGLETR 233.47 8.591900000000001e-32 99667000.0 108408.0 117941.0 157083.0 217020.0 199984.0 169694.0 132127.0 199248.0 157641.0 177425.0 True False 142879.4889735208 156063.12178804036 154999.97678379124 166989.3919255762 172219.67357511373 159083.00735426683 143886.0470360852 168458.79986354924 165973.58142951995 171213.404753967 0.8345111130687347 0.9115122849890314 0.9053028120463208 0.9753289595843229 1.005877278257463 0.9291504224384094 0.8403900806881849 0.9839112778910265 0.9693959516080142 1.0 17.385436133039207 -4.642025611810033 1.2020962416370886 0.9510496539043395 0.7562369671789291 0.38362799273251624 0.04642312469226244 2.3914794934615706 2.382859147717739 0.01497437412445694 0.6315343802872069 2.2802075965044242e-05 4.642025611810033 -0.1948126867254104 GGPAS(ph)PGGLQGLETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GGPASPGGLQGLETR 15 0 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3 C9JWC4 HJURP Holliday junction recognition protein 1 GGPAS(1)PGGLQGLETR;GGPAS(1)PGGLQGLETR;GGPAS(1)PGGLQGLETR;GGPAS(1)PGGLQGLETR;GGPAS(1)PGGLQGLETR 189.52 2.0019000000000002e-07 163175300.0 105557.3 105038.1 133480.0 134790.0 157470.0 136471.1 134996.0 123221.0 133221.0 108685.7 True False 123426.06603829245 115465.58839538088 136662.66942571918 127238.15329507603 126614.88390785323 129314.31527235886 122208.20159359719 119986.57931344154 135169.10509562923 128389.5570544721 0.9613403836725305 0.8993378514920186 1.064437580135408 0.9910319516180933 0.9861774338401532 1.0072027526155762 0.9518546866062297 0.9345509250610982 1.052804513051484 1.0 16.970168335787783 -5.236432789475614 24.99980238831836 0.9941070553305008 0.9303391195639945 0.31373456290396484 0.03990575308742192 977.6875715212183 977419.2127715185 0.010077131928425099 0.026636195217443037 5.8018595396507815e-06 5.236432789475614 -0.0637679357665063 GGPAS(ph)PGGLQGLETR ddPTM_PC-9_Lapatinib_30min_R1 4 GGPASPGGLQGLETR 15 0 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3 C9JWC4 HJURP Holliday junction recognition protein 1 GGPAS(1)PGGLQGLETR;GGPAS(1)PGGLQGLETR;GGPAS(1)PGGLQGLETR;GGPAS(1)PGGLQGLETR 205.12 8.0435e-13 226653000.0 377180.0 357096.0 395181.0 350978.0 355960.0 367612.0 324678.0 291504.0 387383.0 313861.0 True False 371801.34403365897 356269.1661519134 362690.74362277356 376790.09294828604 335023.13264428626 351890.09170542704 341488.2381783454 305048.34002767166 343751.8472161654 368111.45565650525 1.010023834684995 0.9678296088789962 0.9852742642196121 1.0235761130451726 0.9101133026321936 0.9559335529991906 0.9276762049399443 0.8286847239883796 0.9338254540410976 1.0 18.489783121636826 -6.271501112923648 24.719412187747103 0.919049706424996 0.9938010956736703 0.38832668799105075 0.04283544362896482 597.2394084911601 1467280.0474431335 0.013333009202204909 0.015293403543308132 5.351787823196319e-07 6.271501112923648 0.0747513892486743 GGPASVPS(ph)SSPGTSVK ddPTM_PC-9_AZD4547_30min_R2 1 GGPASVPSSSPGTSVK 16 0 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 GGPASVPS(0.323)S(0.323)S(0.323)PGT(0.032)SVK 169.17 3.506e-21 0.0 13759.0 14538.0 15184.0 17946.0 18534.0 15497.0 13067.0 19344.0 15041.0 16477.0 True False 18134.075795021363 19237.124193915013 14982.650238950653 13808.826962936093 15960.874020127396 14527.970140188092 14229.937685866802 16354.829280898686 15836.036553189912 15900.145245208469 1.1404974932846033 1.2098709727014694 0.9422964386734578 0.8684717497846381 1.003819384916451 0.9137004672687576 0.8949564589766885 1.0285962190079514 0.9959680436228797 1.0 13.956752323900897 -5.265370564684077 24.933136000637354 0.9518918001617906 1.1751842431017425 0.7397971013926011 0.05195641250673084 141.611647680953 898162.7718018756 0.013846849029176888 0.030631156606394917 5.4278699719743875e-06 5.265370564684077 0.22329244293995187 GGPASVPS(ph)SSPGTSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GGPASVPSSSPGTSVK 16 0 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 GGPASVPS(0.654)S(0.166)S(0.166)PGT(0.013)S(0.001)VK;GGPASVPS(0.435)S(0.281)S(0.281)PGT(0.002)SVK;GGPASVPS(0.436)S(0.282)S(0.282)PGTSVK;GGPASVPS(0.412)S(0.294)S(0.294)PGTSVK 200.19 1.1426999999999998e-22 47737800.0 191339.0 180848.0 189444.0 188990.0 213002.0 166630.0 173804.0 149262.0 129037.0 122816.0 True False 223728.9135824881 198801.39425720595 193961.06343037038 178401.50301384673 171265.78714765122 157891.62946464992 157340.0268880084 145344.03065616198 130923.92201097976 145081.56858907882 1.5420905340234208 1.3702732620728706 1.3369104381531414 1.2296634558669646 1.1804792904654564 1.0882955774475642 1.0844935605407588 1.0018090655459244 0.902415953206307 1.0 17.146504723034177 -5.375719020493223 0.38998136636288216 0.9403728097579028 1.7622520784307079 0.9521062967719103 0.04110193580918275 0.7256163417885537 0.12324053805748901 0.03743329274701335 0.26761150941741535 4.209989178451974e-06 5.375719020493223 0.821879268672805 GGPASVPS(ph)SSPGTSVK ddPTM_PC-9_Lapatinib_30min_R1 1 GGPASVPSSSPGTSVK 16 0 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 GGPASVPS(0.567)S(0.344)S(0.081)PGT(0.008)SVK 198.85 4.5693e-12 27621000.0 62797.0 62703.0 78537.0 63132.0 63951.0 54182.0 50633.0 43731.0 55303.0 40960.0 True False 61901.50326444057 62557.81505596082 72079.99102158706 67774.93788217826 60189.52791250352 51864.7621644109 53254.5289908283 45762.901907864405 49074.19377359254 48039.881424230676 1.288544047763163 1.302205858992972 1.500419836282753 1.4108056862936693 1.2529075036839024 1.0796188630526262 1.1085483022022495 0.9526023077313885 1.0215302852275603 1.0 15.551944969625355 -6.707758424628669 1.9102231604441307 1.0177075319796596 1.3797000787551155 0.8607403834472109 0.06581041403321852 0.1260443479438477 0.9475989646440149 0.028534829185585926 0.02716959001478678 1.9599345797427772e-07 6.707758424628669 0.3619925467754559 GGPASVPSS(ph)SPGTSVK ddPTM_PC-9_AZD4547_30min_R2 1 GGPASVPSSSPGTSVK 16 0 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 GGPASVPS(0.061)S(0.454)S(0.454)PGT(0.028)S(0.003)VK 174.59 3.2308999999999998e-22 0.0 15765.0 15472.0 17305.0 19002.0 20503.0 18294.0 13903.0 18343.0 14745.0 17546.0 True False 20777.94206762932 20473.021428549546 17075.524393113858 14621.382477973459 17656.51235754138 17150.073288030006 15140.340066320205 15508.51083020703 15524.39059748588 16931.71988058675 1.2271607500105468 1.209151909725551 1.0084932017267774 0.8635497504738291 1.042806784075471 1.0128961150422535 0.8941997725629474 0.9159442123767052 0.916882083271738 1.0 14.047440905480522 -5.312199151024561 3.4991394749256854 0.9494103470234354 1.225442165024755 0.7977874664227468 0.053277947831716986 0.09760317139107723 2.4184053284232396 0.01485461680384718 0.03740507114500941 4.873049792266869e-06 5.312199151024561 0.2760318180013195 GGPASVPSS(ph)SPGTSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGPASVPSSSPGTSVK 16 0 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 GGPASVPS(0.24)S(0.458)S(0.257)PGT(0.043)S(0.002)VK;GGPASVPS(0.076)S(0.456)S(0.456)PGT(0.013)S(0.001)VK 217.39 3.9611000000000003e-22 12049500.0 85223.0 78783.0 84495.0 93506.0 96600.0 75922.0 82525.0 68784.0 74052.0 54003.0 True False 99649.57066902424 86604.05558129144 86509.68124907199 88267.1619705421 77671.9234489022 71940.5166669576 74707.63457073974 66978.49288267235 75134.87040737979 63793.31641248722 1.562069136282094 1.3575725554274387 1.3560931789421462 1.3836427847677197 1.2175558164538114 1.1277124425040177 1.1710887405144546 1.0499296266334517 1.177785928569039 1.0 15.961117661162548 -1.8510105155939856 0.19555088260928324 0.979438912203785 3.308316802936917 0.8757483853473577 0.05761082651142101 15.365968994678802 0.2047338132655839 0.11295058565775663 10.604968425271931 0.01409254675654907 1.8510105155939856 2.328877890733132 GGPASVPSS(ph)SPGTSVK ddPTM_PC-9_Lapatinib_30min_R1 1 GGPASVPSSSPGTSVK 16 0 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 GGPASVPS(0.128)S(0.435)S(0.435)PGT(0.002)SVK 165.78 5.2706999999999995e-05 29611000.0 61601.0 63435.0 76140.0 61679.0 58723.0 56759.0 52600.0 48760.0 58962.0 43756.0 True False 60722.55844376016 63288.120154934746 69880.06310889944 66215.07941511243 55269.02859386002 54331.549881691324 55323.37062622337 51025.56760713152 52321.07866261439 51319.16629879486 1.183233532871833 1.2332258046916276 1.3616757275836815 1.290260232007459 1.0769666107213811 1.0586989968885603 1.0780255139788297 0.994278966069832 1.0195231613465057 1.0 15.64721011298632 -6.340126180090185 4.0291455379239585 1.0361425086901308 1.2718413226889647 0.8422565367037338 0.04879976554506492 0.09513114578244512 2.9259999792470293 0.016988809574406193 0.01966737969493171 4.5695540632224404e-07 6.340126180090185 0.23569881399883386 GGPASVPSSS(ph)PGTSVK ddPTM_PC-9_AZD4547_30min_R2 2 GGPASVPSSSPGTSVK 16 0 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 GGPASVPS(0.005)S(0.342)S(0.637)PGT(0.016)SVK;GGPASVPS(0.017)S(0.152)S(0.798)PGT(0.029)S(0.003)VK 249.36 2.7534e-47 60063000.0 223700.0 192121.0 205692.0 279390.0 245930.0 225787.0 186931.0 256410.0 206176.0 218097.0 True False 294831.9467509476 254220.35611907733 202964.3896832346 214980.95203247052 211786.86456080375 211668.50319691913 203567.49686666948 216787.72621563455 217074.04244335377 210461.4904135601 1.400883107743836 1.207918634518507 0.96437780272489 1.0214740549923391 1.006297466318609 1.0057350766688349 0.9672434442360747 1.0300588758049907 1.0314192967882148 1.0 17.683196752042257 -4.978840569844657 2.565626222939645 1.003781252574712 1.415116109515649 0.9618695911323143 0.025334700660286594 0.05826965108542165 0.6604861767297077 0.0068923948204833935 0.04341984049690737 1.0499277879798807e-05 4.978840569844657 0.41133485694093697 GGPDDRGFRDDFLGGRGGSR ddPTM_PC-9_Lapatinib_30min_R1 1 GGPDDRGFRDDFLGGRGGSR 20 3 Q15056-2 Q15056-2 EIF4H Eukaryotic translation initiation factor 4H 0 95.01799999999999 0.0015698 0.0 11641.0 8014.7 15092.0 8901.6 12266.0 11864.0 8998.4 12038.0 12767.0 8478.3 False True 11474.997205302048 7996.142454571704 13851.194016804713 9556.253358867098 11544.537995883857 11356.604376334786 9464.29312249065 12597.329426879596 11329.0460175299 9943.762858375365 1.153989427215369 0.8041364791635962 1.3929529710313058 0.9610298933082582 1.1609828352010831 1.1420831870270742 0.9517818613824977 1.2668573865143218 1.1393117654638905 1.0 13.279576175669808 -5.2358697336699995 24.982527693769388 1.1259905950906741 0.9790630612671244 0.1332194910082234 0.15079993530966015 1470.7367341685103 1436961.6883444178 0.035530096082795115 0.09392906398441159 5.809386435355552e-06 5.2358697336699995 -0.14692753382354973 GGPEGVAAQAVASAASAGPADAEMEEIFDDAS(ph)PGK ddPTM_PC-9_AZD4547_30min_R2 2 GGPEGVAAQAVASAASAGPADAEMEEIFDDASPGK 35 0 O60264 O60264 SMARCA5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 1 GGPEGVAAQAVASAASAGPADAEMEEIFDDAS(1)PGK;GGPEGVAAQAVASAASAGPADAEMEEIFDDAS(1)PGK 147.16 2.3837e-24 3743900.0 63084.0 72796.0 62655.0 42654.0 47368.0 65123.0 71462.0 77654.0 63473.0 56949.0 True False 83143.39977128635 96325.88339663218 61824.15376195025 32820.77929773076 40791.77083119646 61050.848515162295 77821.9795597621 65654.35861139913 66828.05319730223 54955.232843926504 1.512929624143611 1.7528063918899008 1.1249912076167807 0.5972275541246846 0.7422727321899547 1.1109196587074321 1.4160977132200936 1.1946880253943837 1.2160453106821452 1.0 15.74596924086124 -10.819719203443713 15.955841896988021 1.000040391044632 1.1747922924084861 0.028064075105453945 0.3218659926160738 0.0 0.0 0.35420842594572133 0.0859081619798812 1.5145401699470503e-11 10.819719203443713 0.1747519013638541 GGPEGVAAQAVASAASAGPADAEMEEIFDDAS(ph)PGK ddPTM_PC-9_Lapatinib_30min_R1 1 GGPEGVAAQAVASAASAGPADAEMEEIFDDASPGK 35 0 O60264 O60264 SMARCA5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 1 GGPEGVAAQAVASAASAGPADAEMEEIFDDAS(1)PGK 113.75 6.5056e-24 2889500.0 11555.0 31706.0 24024.0 20952.0 27914.0 27757.0 30878.0 29094.0 23850.0 24964.0 True False 11390.223581072521 31632.586705010828 22048.839455321777 22492.87997382309 26272.153401035528 26569.897814727294 32476.71175278566 30445.813452868828 21163.76184836595 29278.99413756092 0.3890237324259863 1.080385021302032 0.7530600044431223 0.7682258436934423 0.8973038239497433 0.9074730398829437 1.1092154190885442 1.0398517554881108 0.7228309056292257 1.0 14.8375783710922 -6.484185417817373 1.933949397303809 0.9706518886594013 0.7687831751095354 0.22318249494272013 0.1819791148836104 0.5655558041441098 4.236018497723925 0.06547132931881043 0.07297349490346063 3.2795524590753327e-07 6.484185417817373 -0.2018687135498659 GGPEGVAAQAVASAASAGPADAEMEEIFDDAS(ph)PGKQK ddPTM_PC-9_AZD4547_30min_R2 1 GGPEGVAAQAVASAASAGPADAEMEEIFDDASPGKQK 37 1 O60264 O60264 SMARCA5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 1 GGPEGVAAQAVASAASAGPADAEMEEIFDDAS(1)PGKQK 83.639 9.175e-11 4842800.0 36530.0 27685.0 39097.0 33819.0 36634.0 35258.0 37762.0 35742.0 31321.0 43199.0 True False 48145.78012879792 36633.63484031762 38578.54823447403 26022.55204834145 31548.001448869494 33053.31168631037 41122.74484531279 30218.89516945207 32976.56411691119 41686.61615875223 1.1549457491451862 0.8787864839114864 0.9254420672466683 0.6242423695231483 0.7567896930930408 0.7928998496888247 0.9864735647697551 0.7249064077154058 0.7910587895004201 1.0 15.347296648094888 -4.486575434431385 1.5085374555797322 0.808960742072843 1.5450351132561488 0.4354546835197828 0.11165694797513995 2.2376242896990304 2.6987839210714064 0.031268174106661384 3.045208446816617 3.261553941746252e-05 4.486575434431385 0.7360743711833059 GGPEGVAAQAVASAASAGPADAEMEEIFDDAS(ph)PGKQK ddPTM_PC-9_Lapatinib_30min_R1 1 GGPEGVAAQAVASAASAGPADAEMEEIFDDASPGKQK 37 1 O60264 O60264 SMARCA5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 1 GGPEGVAAQAVAS(0.001)AAS(0.004)AGPADAEMEEIFDDAS(0.996)PGKQK 70.264 1.1826000000000001e-06 4927500.0 43748.0 52723.0 46026.0 48716.0 41577.0 47369.0 42641.0 41691.0 45421.0 34646.0 True False 43124.14549759934 52600.92313279147 42241.91994549787 52298.73715181201 39131.522603527046 45343.13829253224 44848.7423359846 43628.11606047825 40305.20867566582 40634.51493710685 1.0612688637810956 1.2944887668575826 1.0395576275705254 1.2870520844843054 0.9630119287530293 1.1158774348042124 1.103710537837118 1.0736713881783708 0.9918958978112394 1.0 15.310418052154146 -7.1256095372896215 0.4253208498699387 0.9949186604948584 1.1800698596488783 0.2324557045841018 0.09552921973923546 1.694255742067207 0.6876682965323151 0.09451769689973541 0.11331471864310241 7.488424624454033e-08 7.1256095372896215 0.1851511991540199 GGPGAAPGGAS(ph)PASSSSAASSPSSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGPGAAPGGASPASSSSAASSPSSGR 26 0 Q9BXK1 Q9BXK1 KLF16 Krueppel-like factor 16 1 GGPGAAPGGAS(0.644)PAS(0.251)S(0.075)S(0.022)S(0.007)AAS(0.001)S(0.001)PSSGR 157.7 1.7315999999999997e-10 3074100.0 13207.0 14177.0 16292.0 17100.0 16440.0 16822.0 16336.0 17169.0 12947.0 13379.0 True False 15442.684249859816 15584.398867471049 16680.46306775407 16141.942438948005 13218.70001552746 15939.824706561478 14788.535817602025 16718.331942059198 13136.325381682414 15804.506791894275 0.9771063692908134 0.9860730912187583 1.0554244613510528 1.0213505964783913 0.8363880119502995 1.008561982759032 0.9357163758622753 1.057820542089526 0.8311759142284464 1.0 13.948048393596624 GGPGAAPGGASPAS(ph)SSSAASSPSSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGPGAAPGGASPASSSSAASSPSSGR 26 0 Q9BXK1 Q9BXK1 KLF16 Krueppel-like factor 16 1 GGPGAAPGGAS(0.174)PAS(0.633)S(0.084)S(0.065)S(0.02)AAS(0.008)S(0.014)PSSGR 122.47 2.9301e-12 2769400.0 8440.3 7422.8 10957.0 10614.0 9859.5 7659.9 8712.5 9523.0 8003.9 7889.6 True False 9869.076086476247 8159.686528423796 11218.256434653906 10019.33199105228 7927.601752012952 7258.201359516718 7887.188926962393 9273.031340452544 8120.94189560886 9319.922025960768 1.058922602462317 0.8755101711897244 1.2036856535285705 1.0750446155175222 0.8506081628076405 0.7787834854517989 0.8462719865029474 0.9949687684749283 0.8713529869657565 1.0 13.186102169452555 -6.259793994268725 24.940734598458267 0.8822990180690857 1.0513346449485692 0.4014385716174641 0.09717528131897187 151.13261711203867 2290863.800212117 0.03030892173450118 0.03708599208497623 5.498016080565363e-07 6.259793994268725 0.16903562687948348 GGPGAAPGGASPASS(ph)SSAASSPSSGRAPGAAPSAAAK ddPTM_PC-9_AZD4547_30min_R2 1 GGPGAAPGGASPASSSSAASSPSSGRAPGAAPSAAAK 37 1 Q9BXK1 Q9BXK1 KLF16 Krueppel-like factor 16 1 GGPGAAPGGAS(0.007)PAS(0.115)S(0.334)S(0.115)S(0.115)AAS(0.115)S(0.115)PS(0.068)S(0.015)GRAPGAAPSAAAK 81.368 7.9935e-10 4937900.0 13028.0 6481.0 16936.0 35027.0 28203.0 16992.0 12974.0 17969.0 11894.0 19220.0 True False 17170.63300076593 8575.856507137385 16711.417574214174 26952.066311755425 24287.500269216212 15929.487553854038 14128.660866031672 15192.30393654201 12522.692557917742 18547.113650112704 0.9257846436209006 0.46238226976547764 0.9010252424971055 1.4531676906822453 1.3095029624228687 0.8588661208617353 0.7617714072693903 0.819119579636031 0.6751828232767445 1.0 14.178907067922879 -10.888658423862317 5.075861306830235 1.0000520843893255 0.913713043987931 0.009797271750774827 0.27269143415135216 0.00017955321520242928 2.2434933222535208e-05 0.29494186304067677 0.07149077978249012 1.292235227536118e-11 10.888658423862317 -0.0863390404013945 GGPGAAPGGASPASSSSAAS(ph)SPSSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGPGAAPGGASPASSSSAASSPSSGR 26 0 Q9BXK1 Q9BXK1 KLF16 Krueppel-like factor 16 1 GGPGAAPGGASPASSSSAAS(0.69)S(0.31)PSSGR 184.97 1.4032e-23 12332000.0 11575.0 14234.0 16989.0 18315.0 21696.0 18737.0 19022.0 17388.0 16249.0 13692.0 True False 13534.418883329088 15647.057450771166 17394.082191141282 17288.869928031145 17444.82454603916 17754.398735396648 17220.098452646045 16931.583424108878 16486.610884912152 16174.251214187647 0.8367879726918694 0.9674053681722193 1.0754180803055433 1.0689131570347925 1.0785553108472186 1.0976952503262059 1.0646612461132672 1.0468233243005969 1.0193121565003584 1.0 13.981411303848637 -4.883856057219361 2.3147732073079292 1.0611440548728759 0.8078211293633821 0.8528389851911494 0.028207507781978516 0.15968413788950953 1.2364661779644353 0.007617682633511366 0.07637483591735227 1.3066038778165183e-05 4.883856057219361 -0.25332292550949376 GGPGAAPGGASPASSSSAAS(ph)SPSSGR ddPTM_PC-9_Lapatinib_30min_R1 1 GGPGAAPGGASPASSSSAASSPSSGR 26 0 Q9BXK1 Q9BXK1 KLF16 Krueppel-like factor 16 1 GGPGAAPGGAS(0.001)PAS(0.007)S(0.043)S(0.001)SAAS(0.746)S(0.2)PS(0.001)SGR 175.23 1.7268e-17 14484000.0 7953.8 11714.0 13723.0 9804.2 14604.0 13318.0 11272.0 11480.0 13176.0 11268.0 True False 7840.377353451719 11686.87695270602 12594.747912311886 10525.233573852442 13745.021432568712 12748.420185774337 11855.609005680408 12013.40270980044 11691.980130568963 13215.658786333772 0.5932642087853692 0.8843204218310587 0.9530170319875415 0.7964214076665265 1.0400557138159734 0.9646450768657403 0.8970880072917906 0.9090279118149921 0.8847065681401797 1.0 13.689960723112923 -4.761362545401569 3.7633750684611114 0.9263515253369168 0.5510930818292537 0.7147747350403548 0.06350446077150286 0.1480117158694916 3.634682414414598 0.015776523934385688 0.15995740924011026 1.732357236632352e-05 4.761362545401569 -0.37525844350766313 GGPGAAPGGASPASSSSAAS(ph)SPSSGRAPGAAPSAAAK ddPTM_PC-9_AZD4547_30min_R2 1 GGPGAAPGGASPASSSSAASSPSSGRAPGAAPSAAAK 37 1 Q9BXK1 Q9BXK1 KLF16 Krueppel-like factor 16 1 GGPGAAPGGAS(0.003)PAS(0.026)S(0.089)S(0.089)S(0.089)AAS(0.331)S(0.331)PS(0.032)S(0.01)GRAPGAAPSAAAK 65.07300000000001 2.8102e-06 4320400.0 13565.0 3923.8 16364.0 35441.0 27557.0 16626.0 13471.0 16891.0 13079.0 19103.0 True False 17878.38783047203 5192.091615908915 16147.002667952349 27270.625007991664 23731.186218444538 15586.373591712407 14669.892903215094 14280.884066566368 13770.329238692297 18434.209784500672 0.9698483438928871 0.2816552310408435 0.875925947285715 1.4793487394789537 1.2873449144751254 0.8455135193707787 0.7957972202068252 0.7746946700462103 0.7469986183118233 1.0 14.17009795359351 -14.235929887463575 11.10015624337797 0.8277166732492589 0.9030868678730398 0.0 0.3059689678440108 0.0 0.0 0.0 0.07694243743959987 5.808581837446467e-15 14.235929887463575 0.07537019462378092 GGPGAAPGGASPASSSSAAS(ph)SPSSGRAPGAAPSAAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGPGAAPGGASPASSSSAASSPSSGRAPGAAPSAAAK 37 1 Q9BXK1 Q9BXK1 KLF16 Krueppel-like factor 16 1 GGPGAAPGGAS(0.047)PAS(0.156)S(0.156)S(0.037)S(0.037)AAS(0.288)S(0.255)PS(0.023)S(0.002)GRAPGAAPSAAAK 74.81 2.2308000000000003e-06 0.0 4557.8 2540.6 3125.9 5575.3 6546.3 8905.2 5413.6 6779.0 6789.3 4249.9 True False 5329.345519346637 2792.813977759535 3200.4333110417656 5262.93401636648 5263.599508007747 8438.195635291362 4900.784616930109 6601.0584329442145 6888.580668406305 5020.373227810109 1.061543689585665 0.5562960861732112 0.6374891199947295 1.048315290029179 1.0484478482297488 1.6807905015006446 0.9761793385763544 1.3148541220756214 1.372125209784674 1.0 12.293578906586188 -6.0943366750001475 2.2093551239987383 1.2655087939873304 0.7384710433319274 0.4568073182501504 0.2318923079387615 0.25632056915780943 2.468912205653963 0.07264110443304791 0.10521766410811123 8.047543353812024e-07 6.0943366750001475 -0.527037750655403 GGPGAAPGGASPASSSSAASS(ph)PSSGR ddPTM_PC-9_AZD4547_30min_R2 2 GGPGAAPGGASPASSSSAASSPSSGR 26 0 Q9BXK1 Q9BXK1 KLF16 Krueppel-like factor 16 1 GGPGAAPGGASPASSSSAAS(0.08)S(0.854)PS(0.059)S(0.007)GR;GGPGAAPGGASPASSSSAAS(0.232)S(0.764)PS(0.003)S(0.001)GR 308.38 9.191099999999998e-173 29172000.0 28513.8 30956.2 38225.0 42340.7 41574.0 45404.0 36988.8 51825.0 43598.2 43519.0 True False 37580.59527611601 40962.18626851507 37718.11152422871 32579.705772293997 35802.167719476485 42564.88070240051 40280.73154319963 43816.63707002558 45902.71184451063 41995.4130561527 0.8948738098102864 0.9753966751974534 0.8981483638176212 0.7757920068253926 0.8525256715919157 1.013560234435279 0.9591697905040167 1.0433672127819698 1.0930410848235599 1.0 15.357944137856816 -6.770691733875028 23.51350266416546 1.0206220829255694 0.8799748138540363 0.6186521690103329 0.05592716940432819 73.27723087572942 186221.25151990625 0.02185926857574973 0.019569545423281334 1.69554088356917e-07 6.770691733875028 -0.14064726907153313 GGPGAAPGGASPASSSSAASS(ph)PSSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGPGAAPGGASPASSSSAASSPSSGR 26 0 Q9BXK1 Q9BXK1 KLF16 Krueppel-like factor 16 1 GGPGAAPGGASPASSSSAAS(0.048)S(0.939)PS(0.01)S(0.003)GR;GGPGAAPGGASPASSS(0.002)S(0.019)AAS(0.155)S(0.822)PSSGR 342.82 2.6596999999999984e-259 11667000.0 7711.93 10576.98 14825.4 14310.6 16670.1 12318.3 17201.7 13749.6 10939.2 12154.400000000001 True False 9017.407431439491 11626.992673574374 15178.893761642596 13508.823477591186 13403.713572314131 11672.306662872197 15572.230446476784 13388.68756890542 11099.165105066833 14357.896505822546 0.6280451616142149 0.809797777053156 1.0571808868720507 0.94086368933729 0.933542985692823 0.8129538096432675 1.0845760338334929 0.9324964533262875 0.7730355975588623 1.0 13.809556783104153 -4.92034860350266 3.504316339482193 0.9398059144280868 0.6283084365889426 0.5312954394185473 0.0914274955647769 0.19405050842989804 4.342226006897914 0.02313542705726569 0.13062852318204496 1.201299777117715e-05 4.92034860350266 -0.31149747783914417 GGPGAAPGGASPASSSSAASS(ph)PSSGR ddPTM_PC-9_Lapatinib_30min_R1 1 GGPGAAPGGASPASSSSAASSPSSGR 26 0 Q9BXK1 Q9BXK1 KLF16 Krueppel-like factor 16 1 GGPGAAPGGASPASSSSAAS(0.221)S(0.744)PS(0.033)S(0.001)GR 300.92 7.397099999999999e-154 11160000.0 8027.4 12690.0 12867.0 11084.0 14815.0 12664.0 14623.0 13190.0 13148.0 12596.0 True False 7912.927803955136 12660.61708467127 11809.124928056337 11899.154335140076 13943.610827410674 12122.390241225863 15380.107389111477 13802.855552462364 11667.13378542204 14773.201816885005 0.5356271377076207 0.8569988579050508 0.7993612403344493 0.8054553428993273 0.9438448753521967 0.8205662111358012 1.0410815190741394 0.9343171320306757 0.7897498409645437 1.0 13.850694916873403 -4.19072878205042 0.8176955809424953 0.9113682208751682 2.3109694811851767e-39 0.6022478694569663 0.08526488911241294 4.187211965062047 1.0895747137028777 0.030441902895808084 4.339735453484108 6.445716764126378e-05 4.19072878205042 -0.9113682208751682 GGPGS(ph)AVSPYPTFNPSSDVAALHK ddPTM_PC-9_AZD4547_30min_R2 2 GGPGSAVSPYPTFNPSSDVAALHK 24 0 P04083;Q5T3N0;Q5T3N1 P04083;Q5T3N1 ANXA1 Annexin A1;Annexin 1 GGPGS(0.85)AVS(0.149)PY(0.001)PTFNPSSDVAALHK;GGPGS(0.995)AVS(0.005)PYPTFNPSSDVAALHK 152.92 3.4643999999999997e-07 14040700.0 25966.5 30923.0 47038.0 56316.0 47406.0 35800.0 24035.0 40823.0 31998.0 38439.0 True False 34223.306863247504 40918.255017776486 46414.24538591681 43333.21627352664 40824.4951871242 33561.42034062942 26174.068438035385 34514.74336921667 33689.348954788315 37093.262309921025 0.9226286590083527 1.1031182610981192 1.2512850716153585 1.168223380070204 1.1005905828942204 0.9047848113282024 0.7056286454220778 0.9304855173114632 0.9082336482919084 1.0 15.17886953634622 -6.772778614450054 4.539386646095403 0.8709217323734365 1.1220753660583251 0.5241054987251184 0.1039714942157486 0.1521294747403989 7.64319141841734 0.038040881286094556 0.03522846407710677 1.6874129802518667e-07 6.772778614450054 0.25115363368488863 GGPGS(ph)AVSPYPTFNPSSDVAALHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGPGSAVSPYPTFNPSSDVAALHK 24 0 P04083;Q5T3N0;Q5T3N1 P04083;Q5T3N1 ANXA1 Annexin A1;Annexin 1 GGPGS(0.924)AVS(0.073)PY(0.002)PT(0.001)FNPSSDVAALHK;GGPGS(0.391)AVS(0.23)PY(0.281)PT(0.097)FNPSSDVAALHK 94.76700000000001 3.6122000000000003e-06 3318000.0 13109.7 14912.0 13978.599999999999 19955.1 20807.2 24340.0 19014.8 16592.8 14332.0 13261.1 True False 15328.913281622414 16392.36481002527 14311.902838135707 18837.0804423071 16730.178525734966 23063.56755187886 17213.580488769523 16157.256581524827 14541.57838651984 15665.232455190151 0.978530853306533 1.0464169527592428 0.9136093498181023 1.2024769179895611 1.0679815044935372 1.4722773899366886 1.0988397738755789 1.031408670617694 0.9282708333958986 1.0 13.93527855745898 -5.7610028158361235 24.99996032351527 1.1280946914941246 0.9862088435607866 0.15341965669516433 0.14251477173337107 22.055185403648863 1262824.1800442282 0.041369547306814025 0.06638681915551732 1.7337927563216438e-06 5.7610028158361235 -0.14188584793333792 GGPGS(ph)AVSPYPTFNPSSDVAALHK ddPTM_PC-9_Lapatinib_30min_R1 1 GGPGSAVSPYPTFNPSSDVAALHK 24 0 P04083;Q5T3N0;Q5T3N1 P04083;Q5T3N1 ANXA1 Annexin A1;Annexin 1 GGPGS(0.99)AVS(0.01)PYPTFNPSSDVAALHK 114.2 1.2903e-08 4394400.0 14294.0 12484.0 14106.0 10476.0 13712.0 13918.0 12365.0 12186.0 11334.0 11632.0 True False 14090.164938801436 12455.09406501468 12946.259130734656 11246.439986911544 12905.487118829233 13322.75958444265 13005.199197590344 12752.206047180158 10057.445567688872 13642.57570133426 1.0328082648955652 0.9129576655965748 0.9489600361512742 0.8243633924502708 0.9459714500662114 0.9765574973602432 0.953280339600272 0.9347359564904577 0.7372101711486374 1.0 13.735828428657587 -8.051857269698653 24.99646533687865 0.8577276781023332 0.9386259785643205 0.12118110093777779 0.07691897432803706 628.4102186160175 302904.99434843665 0.04915696479142767 0.018579992136714695 8.874476225923396e-09 8.051857269698653 0.08089830046198732 GGPGSAVS(ph)PYPTFNPSSDVAALHK ddPTM_PC-9_AZD4547_30min_R2 4 GGPGSAVSPYPTFNPSSDVAALHK 24 0 P04083;Q5T3N0;Q5T3N1 P04083;Q5T3N1 ANXA1 Annexin A1;Annexin 1 GGPGS(0.001)AVS(0.999)PYPTFNPSSDVAALHK;GGPGS(0.036)AVS(0.946)PY(0.016)PT(0.002)FNPSSDVAALHK;GGPGS(0.01)AVS(0.988)PY(0.002)PT(0.001)FNPSSDVAALHK;GGPGS(0.001)AVS(0.998)PY(0.001)PTFNPSSDVAALHK 149.97 4.5238e-07 177000000.0 246392.0 243009.0 384520.0 573020.0 486640.0 404902.0 347866.0 467739.0 379114.0 415255.0 True False 324739.53072802484 321556.90695000003 379421.0135590948 440919.09207074787 419078.4360178491 379583.41393188585 378825.4000942635 395460.6851229469 399153.19206342887 400717.04884378414 0.8103960928665692 0.8024537710032797 0.9468551803669542 1.1003252627832067 1.0458213276102035 0.9472604547950316 0.9453688112031018 0.9868826052297905 0.9960973540185835 1.0 18.612224366184904 -5.354111996871971 3.8663976223139938 1.0008593996602577 0.8050636227494565 0.761634466461446 0.04322920692885339 0.11408830757306683 3.091543360522225 0.012948740358926972 0.029931240081716222 4.424742513584042e-06 5.354111996871971 -0.1957957769108012 GGPGSAVS(ph)PYPTFNPSSDVAALHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GGPGSAVSPYPTFNPSSDVAALHK 24 0 P04083;Q5T3N0;Q5T3N1 P04083;Q5T3N1 ANXA1 Annexin A1;Annexin 1 GGPGS(0.019)AVS(0.946)PY(0.023)PT(0.012)FNPSSDVAALHK;GGPGS(0.007)AVS(0.993)PYPTFNPSSDVAALHK;GGPGSAVS(1)PYPTFNPSSDVAALHK;GGPGS(0.003)AVS(0.992)PY(0.004)PT(0.001)FNPSSDVAALHK 173.18 2.4462e-12 148367000.0 318347.0 321871.0 414948.0 461554.0 541428.0 469607.0 477495.0 421956.0 451135.0 376036.0 True False 372236.8594601437 353824.2257086664 424841.93401905405 435694.62575825874 435339.07007341774 444979.98222412425 432263.2168355695 410880.10209933756 457731.99591143173 444208.35010066244 0.8379780780253023 0.7965276330993912 0.956402404238417 0.9808339389827445 0.9800335134960096 1.0017370950439968 0.9731091654121629 0.9249715859826311 1.030444375500156 1.0 18.760876986942577 -5.329635361566976 4.592055441024107 0.9802977481665249 0.8168796588893623 0.8506770863746903 0.02753455414544709 0.06754668695739705 2.767500006113759 0.007073953953448735 0.015862219865177593 4.681280217766784e-06 5.329635361566976 -0.16341808927716261 GGPGSAVS(ph)PYPTFNPSSDVAALHK ddPTM_PC-9_Lapatinib_30min_R1 4 GGPGSAVSPYPTFNPSSDVAALHK 24 0 P04083;Q5T3N0;Q5T3N1 P04083;Q5T3N1 ANXA1 Annexin A1;Annexin 1 GGPGS(0.004)AVS(0.994)PY(0.001)PT(0.001)FNPSSDVAALHK;GGPGS(0.001)AVS(0.996)PY(0.003)PTFNPSSDVAALHK;GGPGS(0.006)AVS(0.922)PY(0.067)PT(0.006)FNPSSDVAALHK;GGPGS(0.026)AVS(0.759)PY(0.12)PT(0.095)FNPSSDVAALHK 148.84 5.3303e-09 147492000.0 428798.0 328588.0 441698.0 337250.0 391547.0 388989.0 349919.0 370736.0 436728.0 300525.0 True False 422683.2618880766 327827.1746743863 405383.295443587 362052.4900330196 368516.9752710202 372352.8472476472 368036.0936531831 387961.7479983084 387539.0936902798 352470.34582560847 1.1992023354418795 0.9300844129355073 1.150120287407549 1.0271856748259671 1.04552618294122 1.0564090047787338 1.0441618649963706 1.100693299714524 1.0994941795246012 1.0 18.42714235966467 -11.542916264394123 13.522316208152848 0.8730551256875532 1.0680238957440864 0.08677296045222915 0.06921761320132008 0.04196209006282248 6.217996289385092e-05 0.010616357338496139 0.014750541574433255 2.864730260598958e-12 11.542916264394123 0.19496877005653324 GGPGSAVSPY(ph)PTFNPSSDVAALHK ddPTM_PC-9_Lapatinib_30min_R1 1 GGPGSAVSPYPTFNPSSDVAALHK 24 0 P04083;Q5T3N0;Q5T3N1 P04083;Q5T3N1 ANXA1 Annexin A1;Annexin 1 GGPGSAVS(0.119)PY(0.868)PT(0.012)FNPSSDVAALHK 89.756 0.0033734000000000004 0.0 10565.0 7483.6 11825.0 8840.1 9535.7 12510.0 9232.7 9943.8 13233.0 7942.7 True False 10414.341162616283 7466.272183991016 10852.794145820018 9490.230443709122 8974.828873907514 11974.976462234337 9710.724030051952 10405.825249626632 11742.560190332355 9315.585112017507 1.1179481521972607 0.8014818279486495 1.165014759171643 1.01874765026475 0.9634208443149317 1.28547765043616 1.0424169725554542 1.1170339945907068 1.260528463765947 1.0 13.185430672368485 -6.729147064509256 24.99952756371344 1.1422391301033166 1.0102824176267349 0.21738258770267893 0.12113662795100293 293.0122263342036 226838.628732693 0.03822095148467681 0.03821822571885647 1.8657477883884744e-07 6.729147064509256 -0.1319567124765817 GGPGSAVSPYPTFNPSSDVAALHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGPGSAVSPYPTFNPSSDVAALHK 24 0 P04083;Q5T3N0;Q5T3N1 P04083;Q5T3N1 ANXA1 Annexin A1;Annexin 0 ; 179.85 8.613600000000001e-15 14788900.0 96112.0 104971.0 110277.0 128856.0 130618.0 124610.0 122669.0 114330.0 114010.0 103898.0 False True 112381.86330147095 115391.82715082917 112906.42190785123 121636.61607678863 105024.34054915867 118075.23223663193 111048.90427334883 111328.95864264829 115677.18056427086 122733.88494388455 0.9156547383214776 0.9401790483825044 0.9199286892896239 0.9910597723880605 0.8557077827136093 0.9620426526107063 0.904794175822934 0.9070759773761685 0.9425040250062964 1.0 16.905174084412316 -8.55331723537464 17.292709436937088 1.0000000017631738 0.9253943551346966 0.3066251812303422 0.03408007372796199 139.0469083366528 78996.83353974234 0.03078604793046682 0.00794892137815788 2.7969375182460985e-09 8.55331723537464 -0.07460564662847724 GGPGSAVSPYPTFNPSSDVAALHK ddPTM_PC-9_Lapatinib_30min_R1 2 GGPGSAVSPYPTFNPSSDVAALHK 24 0 P04083;Q5T3N0;Q5T3N1 P04083;Q5T3N1 ANXA1 Annexin A1;Annexin 0 ; 177.29 1.5302e-14 79603000.0 206491.0 202495.0 214680.0 225003.0 239240.0 227236.0 223817.0 190178.0 220699.0 220910.0 False True 203546.40047418786 202026.13526875575 197029.8390887643 241550.4712080047 225168.37356393694 217517.6459929883 235405.14911500824 199014.36415892222 195841.5545564998 259093.99915592745 0.7856083164307096 0.7797406961446944 0.7604569759648822 0.9322889453052722 0.8690605506012764 0.8395317788200963 0.9085704411599945 0.7681164550598171 0.7558706693111746 1.0 17.983116076260337 -11.819778347109525 2.4293203082253667 1.92029672763439 0.825161774381306 0.43792959288952993 0.060362674456430114 4514951.766192475 893100.3110612573 23130957.396754455 0.016455670227688596 1.5143339288771368e-12 11.819778347109525 -1.095134953253084 GGPLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 GGPLSPR 7 0 H9KVB4;O15417;O15417-2;H7C177 H9KVB4 TNRC18 Trinucleotide repeat-containing gene 18 protein 1 GGPLS(1)PR 85.161 0.019469999999999998 4842300.0 20951.0 20038.0 28074.0 38504.0 33529.0 26377.0 21626.0 33214.0 24828.0 30502.0 True False 27612.98219212825 26514.891635552973 27701.720416774253 29627.497680869925 28874.07710266815 24727.642020245316 23550.672104886784 28081.539481791217 26140.357392633425 29434.134264086246 0.9381278873155084 0.9008211825650616 0.9411426939970924 1.0065693597456884 0.9809725281405187 0.8401008773822335 0.8001143126408136 0.9540467278514325 0.8880966961045738 1.0 14.84520257433864 -6.75081421461761 24.996052897283008 0.8875773008136068 0.9528574548406107 0.18679024373173225 0.058050417218922304 335.77616159192354 789923.0447053858 0.019868961634794527 0.019673550449449358 1.7749486178309351e-07 6.75081421461761 0.06528015402700393 GGPLS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 GGPLSPR 7 0 H9KVB4;O15417;O15417-2;H7C177 H9KVB4 TNRC18 Trinucleotide repeat-containing gene 18 protein 1 GGPLS(1)PR;GGPLS(1)PR 75.043 0.033296 7465400.0 56963.0 49388.0 54092.0 43017.0 46002.0 48224.0 43432.0 43992.0 54354.0 41460.0 True False 56150.69717426519 49273.645120389694 49644.7645611583 46180.61368050532 43296.25280341179 46161.57193563457 45680.696445591864 46036.028920691766 48232.08014700556 48626.30575802255 1.154739112892639 1.0133125342811045 1.0209446057490748 0.9497043413150148 0.890387458567498 0.949312747823099 0.9394235431519552 0.9467309556637781 0.9918927501303767 1.0 15.56944937073477 -4.168858359293244 0.9536833019475496 0.9489643548955476 1.590534863752517 0.7657862120939793 0.032889799611625706 2.629719711758679 0.8341798548186604 0.011059431316331131 2.3048065882629873 6.778625495061617e-05 4.168858359293244 0.6415705088569693 GGPPFAFVEFEDPRDAEDAVYGR ddPTM_PC-9_AZD4547_30min_R2 1 GGPPFAFVEFEDPRDAEDAVYGR 23 1 J3KTL2;Q07955;Q07955-3;Q07955-2 J3KTL2 SRSF1 Serine/arginine-rich splicing factor 1 0 55.206 0.012496 2633400.0 6376.2 3955.7 6088.3 7745.0 5446.5 6549.8 5418.1 6155.3 4191.9 6044.8 False True 8403.698966801016 5234.302667070416 6007.565163975449 5959.509909057174 4690.34748843336 6140.239970588115 5900.300403749515 5204.13981972269 4413.475276066539 5833.173391893924 1.4406736097506077 0.897333632211974 1.0298965520764165 1.0216582824948788 0.8040816161836208 1.0526414282697145 1.0115078032737503 0.8921627166020177 0.7566165069256692 1.0 12.510065243762773 -4.758161224555918 24.99978308319305 0.9440513559193148 1.440674296270633 0.7086637035535159 0.09615769789118155 51.629519038787635 393671.5084888974 0.02418883895273991 0.16915961972402213 1.745174165957496e-05 4.758161224555918 0.49662294035131815 GGPPFAFVEFEDPRDAEDAVYGR ddPTM_PC-9_Lapatinib_30min_R1 2 GGPPFAFVEFEDPRDAEDAVYGR 23 1 J3KTL2;Q07955;Q07955-3;Q07955-2 J3KTL2 SRSF1 Serine/arginine-rich splicing factor 1 0 ; 79.462 0.00028789999999999995 9202200.0 15275.6 10794.599999999999 13240.6 10586.1 12555.599999999999 8601.3 9370.7 10624.3 12845.2 12114.7 False True 15057.767142798046 10769.605766918248 12152.008978194048 11364.637108194376 11817.104293259357 8233.442449609605 9855.86899481276 11117.943763914009 11398.43831004739 14208.70975317694 1.0597561217288758 0.7579580379921732 0.8552507011044382 0.799835967206899 0.8316803213336917 0.579464468810666 0.6936498222584268 0.782473845764084 0.802214874401161 1.0 13.79448793362304 -4.7591505783352375 24.96434442147381 0.7765605880057207 1.0597564957155627 0.3771568514535526 0.10317823531067712 62.09684878599451 677144.5616336948 0.025622476083081748 0.16597589543367242 1.7412030597882252e-05 4.7591505783352375 0.28319590770984204 GGPPS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GGPPSPTK 8 0 Q5TCQ9-3;Q5TCQ9-2;Q5TCQ9;Q5TCQ9-1 Q5TCQ9-3 MAGI3 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 1 GGPPS(0.964)PT(0.036)K;GGPPS(0.999)PT(0.001)K;GGPPS(0.963)PT(0.037)K;GGPPS(0.979)PT(0.021)K 89.171 0.010425 64752300.0 151727.0 149011.0 143620.0 182414.0 203596.0 157270.0 174816.0 181587.0 164182.0 132184.0 True False 177411.38435515136 163803.82730060842 147044.4454818832 172193.93497416735 163702.82532611475 149022.48434198787 158256.162921763 176820.53365733003 166582.85114817222 156147.91283203175 1.1361751888799994 1.0490298866614511 0.941699718010697 1.1027616818637613 1.048383051409786 0.9543674432734256 1.0135016219653161 1.132391272162157 1.0668272673446832 1.0 17.25255375998485 -10.512917040577438 3.9293004906079005 0.9999952345441825 1.046398413782522 0.05078574940021252 0.06290737309152562 7888282.671301925 5277178.920546562 294.87059511006845 0.015699868767015245 3.0696082924349456e-11 10.512917040577438 0.046403179238339476 GGPPS(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 1 GGPPSPTK 8 0 Q5TCQ9-3;Q5TCQ9-2;Q5TCQ9;Q5TCQ9-1 Q5TCQ9-3 MAGI3 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 1 GGPPS(0.787)PT(0.213)K 74.533 0.027651 34644000.0 74825.0 58155.0 72718.0 77055.0 63047.0 54644.0 56981.0 62921.0 66722.0 51059.0 True False 73757.98177877559 58020.345670532544 66739.40673959751 82721.88174794457 59338.6994151711 52307.00350138557 59931.19736982572 65844.53936440355 59207.06574619171 59884.48011815903 1.2316710712565682 0.9688711592060525 1.1144691681035372 1.3813576002450836 0.9908861076874835 0.8734651014449449 1.0007801228561142 1.0995259411868423 0.9886879810823989 1.0 15.869894536858785 -6.419792068527362 23.879766510366792 0.9916336277759297 1.1590455203078867 0.3981553505741131 0.10891239873354526 29.419742959969756 6804.241841323313 0.03531799442711439 0.040046824006462985 3.8037146694763477e-07 6.419792068527362 0.16741189253195699 GGPS(ph)PGDVEAIK ddPTM_PC-9_AZD4547_30min_R2 1 GGPSPGDVEAIK 12 0 P09661;H0YLR3;H0YMA0 P09661 SNRPA1 U2 small nuclear ribonucleoprotein A 1 GGPS(1)PGDVEAIK 131.79 0.00010607 6263300.0 28550.0 32259.0 33159.0 39098.0 37323.0 32580.0 34941.0 41813.0 35179.0 40969.0 True False 37628.306123109214 42686.09089087252 32719.289994294286 30084.560158078413 32141.34569187521 30542.76744965658 38050.6813103139 35351.76161715347 37038.49012064809 39534.687779993095 0.9517795191024976 1.0797123561065334 0.8276096722041699 0.7609661754633356 0.8129910085729991 0.7725561820451011 0.9624631797287092 0.8941960491475934 0.936860569805531 1.0 15.270831410749812 -10.112210836992226 12.855083025951133 0.9999968789960672 0.8855250522469666 0.11184696775812986 0.09360588578526276 0.0 0.0 0.099612118313181 0.024159487376280507 7.723055628013501e-11 10.112210836992226 -0.1144718267491005 GGPTSHPSPVPPPAS(ph)SPSPLSGSALCGGK ddPTM_PC-9_AZD4547_30min_R2 1 GGPTSHPSPVPPPASSPSPLSGSALCGGK 29 0 J3KR72;P49848-4;P49848-2;P49848;P49848-3 J3KR72 TAF6 Transcription initiation factor TFIID subunit 6 1 GGPT(0.001)S(0.001)HPS(0.003)PVPPPAS(0.428)S(0.383)PS(0.041)PLS(0.042)GS(0.103)ALCGGK 43.312 0.023242 8951900.0 4755.2 4679.0 20667.0 34945.0 21844.0 19377.0 8612.5 27395.0 13639.0 16990.0 True False 6267.254685695586 6191.3952471679995 20392.94207642208 26888.97014486803 18811.337654886313 18165.35312682614 9378.99581537674 23161.732224473708 14359.929695429633 16395.18527135353 0.3822619007938898 0.3776349668939642 1.2438372448314827 1.6400528386739097 1.1473696297750537 1.1079687619368068 0.5720579340914299 1.4127154918427802 0.8758626058663701 1.0 14.000984584333349 -5.2566358964954825 24.69439182432621 1.1385627997086207 0.3799483110402904 0.542442840307394 0.2734771973054585 252.4304271814262 1297714.6126478408 0.07286195047113134 0.18008122153762735 5.538142210176366e-06 5.2566358964954825 -0.7586144886683304 GGPTSHPSPVPPPAS(ph)SPSPLSGSALCGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGPTSHPSPVPPPASSPSPLSGSALCGGK 29 0 J3KR72;P49848-4;P49848-2;P49848;P49848-3 J3KR72 TAF6 Transcription initiation factor TFIID subunit 6 1 GGPTSHPSPVPPPAS(0.421)S(0.421)PS(0.13)PLS(0.014)GS(0.014)ALCGGK 51.966 0.036463 0.0 19902.0 20005.0 22781.0 26184.0 29063.0 22920.0 23421.0 29871.0 24217.0 18213.0 True False 23271.015517582324 21990.96419156085 23324.1854374236 24716.99536967335 23368.313780491153 21718.034851645996 21202.393326644033 29086.917900940665 24571.127810937134 21514.872725971323 1.0816245958773951 1.0221284816161065 1.0840959058646065 1.1488329810027942 1.0861469681055784 1.009442869045162 0.9854761214111164 1.3519446882820214 1.1420531333785908 1.0 14.393046685410708 -7.729006702698977 24.999996412618 1.1852499954307598 1.0616881360993133 0.20804568818003422 0.09119518847063908 236.123327321058 182010.44929021955 0.0417468189131355 0.02410016512194575 1.8663508862211377e-08 7.729006702698977 -0.12356185933144648 GGQEPAGAGSPS(ph)PPEDR ddPTM_PC-9_AZD4547_30min_R2 2 GGQEPAGAGSPSPPEDR 17 0 Q08174-2 Q08174-2 PCDH1 Protocadherin-1 1 GGQEPAGAGS(0.06)PS(0.94)PPEDR;GGQEPAGAGS(0.051)PS(0.949)PPEDR 144.72 9.0006e-09 0.0 3723.7 15181.8 14169.2 12688.7 11112.099999999999 7662.799999999999 11482.4 13082.7 9177.400000000001 7519.599999999999 True False 4907.759142228438 20089.019953719853 13981.307150009186 9763.516253460788 9569.376723808016 7183.643904641764 12504.311355643751 11061.069325538314 9662.49862796657 7256.341092788111 0.6763407452147104 2.76847790047877 1.9267709402338933 1.3455150644950378 1.3187605986877837 0.989981564094527 1.723225410127352 1.5243315031774929 1.3315937749356732 1.0 12.82502655768784 -5.764051041943205 24.44594891810737 1.3440217029775225 1.8883247646871897 0.13993620191831257 0.5163187193290548 83.41647506820267 780821.3925585715 0.13825303186608864 0.21623497916302245 1.7216662183887342e-06 5.764051041943205 0.5443030617096671 GGQEPAGAGSPS(ph)PPEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGQEPAGAGSPSPPEDR 17 0 Q08174-2 Q08174-2 PCDH1 Protocadherin-1 1 GGQEPAGAGS(0.008)PS(0.992)PPEDR;GGQEPAGAGSPS(1)PPEDR 142.72 4.2766e-08 5759200.0 16341.400000000001 14849.6 15484.300000000001 12969.9 28419.0 10919.900000000001 13842.599999999999 8571.0 10796.7 10293.9 True False 19107.67626263792 16323.770150412498 15853.504436534758 12243.238551983137 22850.500957498472 10347.24122061471 12531.328716254755 8346.020331725169 10954.581312150343 12160.102583532436 1.5713416997414225 1.3424039837064057 1.3037311426964469 1.0068367818346604 1.8791371865927582 0.8509172640226936 1.030528207321626 0.6863445661245976 0.9008625738885916 1.0 13.569867779065262 -6.815200220484997 24.999980950227812 0.8826755959190247 1.3868531604635936 0.5765635788759869 0.22476397954533578 70.60302511998903 32831.37665057238 0.07711809442234333 0.06801181995609962 1.5303817552246625e-07 6.815200220484997 0.504177564544569 GGQEPAGAGSPS(ph)PPEDR ddPTM_PC-9_Lapatinib_30min_R1 2 GGQEPAGAGSPSPPEDR 17 0 Q08174-2 Q08174-2 PCDH1 Protocadherin-1 1 GGQEPAGAGS(0.055)PS(0.945)PPEDR;GGQEPAGAGS(0.232)PS(0.768)PPEDR 111.73 0.0014842 3640200.0 40232.0 42937.3 21361.1 15007.6 20874.8 14608.8 11826.42 12745.3 21522.2 9966.6 True False 39658.28430235479 42837.88131990988 19604.872814230534 16111.30896788599 19646.985305435865 13984.015678776104 12438.734160482512 13337.493167005196 19098.14319718666 11689.313530340272 3.392695747224119 3.664704621766004 1.6771620303745793 1.378293851565208 1.6807646791610993 1.1963076909931283 1.064111603149071 1.1409988390153947 1.633812212121469 1.0 13.512902587823339 -5.325398922719731 3.890872473170031 1.3205309924229438 3.55447819290656 0.9362928089958944 0.22892106745951807 0.04800350853423045 1.4406327757195263 0.06345729320700261 0.15041669620441245 4.727168437602326e-06 5.325398922719731 2.233947200483616 GGQGDPAVPAQQPADPS(ph)TPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGQGDPAVPAQQPADPSTPER 21 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 GGQGDPAVPAQQPADPS(0.5)T(0.5)PER;GGQGDPAVPAQQPADPS(0.5)T(0.5)PER 130.66 2.577e-05 231646000.0 55652.0 67239.0 78450.0 67837.0 73168.0 60483.0 72694.0 57184.0 57112.0 45365.0 True False 65072.78442289682 73914.04355292984 80320.54552328183 64036.312820521445 58831.25564088276 57311.16500576374 65807.89806101621 55682.98059145629 57947.1549547112 53589.315390857584 1.2142865410443053 1.3792682928272617 1.4988164140082416 1.1949455288515616 1.0978168915163908 1.0694513372257244 1.2280040821764844 1.0390687058666155 1.081319187081779 1.0 15.709657765135443 -5.963188621946006 5.570551081119544 1.0980192144231622 1.36549003737732 0.6806261024969319 0.0849633447498775 0.10830205687471839 8.720881940994937 0.02452780744866497 0.03624630361241516 1.0884572539936303e-06 5.963188621946006 0.2674708229541578 GGQGDPAVPAQQPADPS(ph)TPER ddPTM_PC-9_Lapatinib_30min_R1 1 GGQGDPAVPAQQPADPSTPER 21 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 GGQGDPAVPAQQPADPS(0.5)T(0.5)PER 122.84 7.286100000000001e-07 21404000.0 52268.0 66768.0 76384.0 68759.0 78288.0 62578.0 65819.0 65127.0 76061.0 57418.0 True False 51522.64873522273 66613.4027982136 70104.00237076657 73815.76623330014 73683.25376012997 59901.6848164429 69226.7857651596 68153.03817780255 67494.20922216195 67342.6247953242 0.7650822772622325 0.9891714645913056 1.041004899702604 1.0961224997934056 1.0941547642979015 0.8895062376689846 1.0279787278200392 1.012034181693117 1.002250943251744 1.0 16.03923233334641 -4.762812387267713 3.813714052468145 1.0215461287061185 0.7339689992374222 0.6615482317892819 0.05443396790142701 0.17079326962981226 4.384578395817872 0.01446286197804064 0.14239125522479215 1.726583605149132e-05 4.762812387267713 -0.2875771294686963 GGQGDPAVPAQQPADPS(ph)TPERQS(ph)SPSGSEQLVR ddPTM_PC-9_AZD4547_30min_R2 1 GGQGDPAVPAQQPADPSTPERQSSPSGSEQLVR 33 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 2 GGQGDPAVPAQQPADPS(0.489)T(0.489)PERQS(0.47)S(0.412)PS(0.062)GS(0.078)EQLVR 68.32600000000001 7.8048e-05 39500000.0 47598.0 31491.0 60797.0 84297.0 81141.0 65948.0 57211.0 63178.0 46473.0 62906.0 True False 62733.1739000964 41669.84990993109 59990.79205594586 64863.62902566723 69875.97274561106 61824.26113474381 62302.66816760735 53415.29178601205 48929.46790349013 60703.68008709625 1.033432796991686 0.6864468488589842 0.988256263374353 1.0685287767167062 1.1510994497426617 1.0184598536042588 1.0263408755155685 0.8799349843267 0.8060379178541935 1.0 15.889496360321466 -3.0729266840967995 11.873426832914035 0.9665210330586262 0.9601518133247261 0.0 0.1298132484285935 0.0 0.0 0.031714724904090184 0.0 0.0008454215538886625 3.0729266840967995 -0.006369219733900144 GGQGDPAVPAQQPADPS(ph)TPERQS(ph)SPSGSEQLVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGQGDPAVPAQQPADPSTPERQSSPSGSEQLVR 33 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 2 GGQGDPAVPAQQPADPS(0.494)T(0.494)PERQS(0.3)S(0.3)PS(0.295)GS(0.118)EQLVR 55.846000000000004 0.003617 18883000.0 14208.0 11108.0 18418.0 22526.0 18935.0 21913.0 21614.0 23507.0 22277.0 16286.0 True False 16613.133779208605 12210.72882978546 18857.154970653966 21263.94125027734 15224.822676034817 20763.843704368184 19566.565448191122 22889.966157725274 22602.75898105656 19238.522880094926 0.8635347881306069 0.6347019938011587 0.9801768611957449 1.1052793077101573 0.791371706181618 1.0792847160761716 1.0170513386157938 1.1897985256138506 1.17486977154792 1.0 14.231710413825317 -5.504590678444533 0.49859267425447823 1.1171141599964947 0.6475363944166921 0.43776133873559564 0.12492201397616641 2.158068550605671 0.6884363615297824 0.09151478211167346 0.5505210941146268 3.1290270786620462e-06 5.504590678444533 -0.4695777655798026 GGQGDPAVPAQQPADPS(ph)TPERQS(ph)SPSGSEQLVR ddPTM_PC-9_Lapatinib_30min_R1 1 GGQGDPAVPAQQPADPSTPERQSSPSGSEQLVR 33 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 2 GGQGDPAVPAQQPADPS(0.492)T(0.492)PERQS(0.5)S(0.166)PS(0.161)GS(0.189)EQLVR 72.11 2.6276e-05 49125000.0 196010.0 119780.0 162110.0 122960.0 113560.0 112130.0 93688.0 97046.0 148180.0 90691.0 True False 193214.86145616788 119502.65676926119 148781.9415626965 132002.88858253587 106880.62406755018 107334.46128779667 98538.70622109523 101555.11144384094 131490.4079954242 106366.81851183859 1.8164956342533 1.1234956393469697 1.3987627311249995 1.241015670388261 1.00483050600648 1.0090972240168148 0.9264045648796754 0.9547630818020367 1.2361976209788523 1.0 16.698688641870206 -1.5228787458689055 0.5589754293209874 1.0200842811871695 34.300469550208106 0.6968875406476429 0.1424655866251625 81.10724709300773 0.7217933841085973 0.0698497083428932 3251.8899105903374 0.02999999995934317 1.5228787458689055 33.28038526902094 GGQGDPAVPAQQPADPS(ph)TPERQSSPSGS(ph)EQLVR ddPTM_PC-9_Lapatinib_30min_R1 1 GGQGDPAVPAQQPADPSTPERQSSPSGSEQLVR 33 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 2 GGQGDPAVPAQQPADPS(0.498)T(0.498)PERQS(0.28)S(0.281)PS(0.073)GS(0.37)EQLVR 72.514 2.0754e-05 44962000.0 105500.0 64070.0 93286.0 69776.0 73664.0 67824.0 58884.0 49312.0 82058.0 52139.0 True False 103995.55065366926 63921.64985144906 85616.38517437354 74907.55980591252 69331.22834899632 64923.3256254661 61932.7253983752 51603.215542306614 72815.76393095241 61151.1566791495 1.70063096597367 1.0453056544267167 1.4000779351335781 1.2249573658751984 1.133768061212094 1.0616859786660877 1.0127809310840425 0.8438632782215482 1.1907503943548488 1.0 15.900092167255352 -1.5228787452803514 0.3568653891191879 0.9922976114007357 7.827459539244069 0.5673672360038631 0.1508223537493469 47.60895892130389 0.6664277826163109 0.12188493683896287 220.3943686790129 0.029999999999999045 1.5228787452803514 6.835161927843333 GGQGDPAVPAQQPADPS(ph)TPERQSSPSGSEQLVR ddPTM_PC-9_AZD4547_30min_R2 1 GGQGDPAVPAQQPADPSTPERQSSPSGSEQLVR 33 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 GGQGDPAVPAQQPADPS(0.46)T(0.46)PERQS(0.062)S(0.009)PS(0.004)GS(0.004)EQLVR 59.236999999999995 0.00032027 5140500.0 7245.3 1802.8 7831.5 32190.0 18554.0 8692.6 5998.2 7448.0 2009.7 9875.6 True False 9549.154688398019 2385.5198443245285 7727.649192988803 24769.092830542333 15978.097365352529 8149.050347847908 6532.028179946905 6297.082738013517 2115.928639116133 9529.858249898702 1.002024840033641 0.2503206009753488 0.8108881570269888 2.599104014039833 1.6766353650142036 0.855107194058687 0.6854276326740052 0.6607740191812876 0.2220314913014183 1.0 13.21823903985826 -6.967864504159074 7.78925827025821 0.6351654688979247 1.2617883784510964 0.1991803626157005 0.5967861699981445 0.3993126799209874 79.9228020513083 0.23937593862891532 0.20949493552416382 1.0768011131651471e-07 6.967864504159074 0.6266229095531717 GGQGDPAVPAQQPADPS(ph)TPERQSSPSGSEQLVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GGQGDPAVPAQQPADPSTPERQSSPSGSEQLVR 33 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 GGQGDPAVPAQQPADPS(0.497)T(0.497)PERQS(0.005)S(0.001)PS(0.001)GSEQLVR;GGQGDPAVPAQQPADPS(0.459)T(0.459)PERQS(0.019)S(0.019)PS(0.019)GS(0.023)EQLVR;GGQGDPAVPAQQPADPS(0.488)T(0.488)PERQS(0.016)S(0.002)PS(0.003)GS(0.003)EQLVR 83.85 3.5069e-10 24858700.0 32440.6 4520.4 16704.300000000003 49800.9 47828.2 99102.0 40847.9 110013.0 84231.0 47423.4 True False 37932.15284894389 4969.155437717156 17102.593863410537 47010.71702969623 38456.60754760645 93904.91666089979 36978.491198814 107125.27531840847 85462.71902560384 56020.88701657219 0.6771073231618546 0.08870183430417966 0.3052895941892391 0.8391640963448052 0.6864690938619047 1.6762483006225997 0.6600840002386068 1.912238113736373 1.5255509788754706 1.0 15.773677206308507 -6.377603802886856 1.1720037135253263 1.3983920346851058 0.32774243356730104 0.5405017537765227 0.3824475589315784 0.34041289873850866 0.9722073514714309 0.16155424872993723 0.21161160925138808 4.1917579541597075e-07 6.377603802886856 -1.0706496011178048 GGQGDPAVPAQQPADPS(ph)TPERQSSPSGSEQLVR ddPTM_PC-9_Lapatinib_30min_R1 3 GGQGDPAVPAQQPADPSTPERQSSPSGSEQLVR 33 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 GGQGDPAVPAQQPADPS(0.444)T(0.444)PERQS(0.051)S(0.019)PS(0.023)GS(0.021)EQLVR;GGQGDPAVPAQQPADPS(0.482)T(0.482)PERQS(0.008)S(0.01)PS(0.01)GS(0.01)EQLVR;GGQGDPAVPAQQPADPS(0.476)T(0.476)PERQS(0.023)S(0.009)PS(0.009)GS(0.008)EQLVR 61.869 0.00015732 23286600.0 297810.0 33745.4 73342.4 50502.9 34900.1 38951.3 16570.0 14585.400000000001 62823.2 24105.7 True False 293563.17478833516 33667.264599611204 67312.47098185116 54217.05173873567 32847.34473423658 37285.44369891512 17427.913522367315 15263.09093062051 55747.38965837582 28272.338126173774 10.3834063344256 1.190819961524263 2.380859718126216 1.9176713116819641 1.1618191812663485 1.3187959033496863 0.6164298631613003 0.5398595214341452 1.971799764476019 1.0 14.787103578726668 -4.760823407191423 24.99948898909802 1.350924475687551 10.383416665319128 0.9589189555395923 0.5612789800137145 2.8593542472618716 115955.81904672536 0.15083717813395295 0.8720869653645449 1.734509140434024e-05 4.760823407191423 9.032492189631578 GGQGDPAVPAQQPADPST(ph)PER ddPTM_PC-9_AZD4547_30min_R2 5 GGQGDPAVPAQQPADPSTPER 21 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 GGQGDPAVPAQQPADPS(0.002)T(0.998)PER;GGQGDPAVPAQQPADPS(0.257)T(0.743)PER;GGQGDPAVPAQQPADPS(0.106)T(0.894)PER;GGQGDPAVPAQQPADPS(0.004)T(0.996)PER;GGQGDPAVPAQQPADPS(0.043)T(0.957)PER 268.25 1.8819999999999995e-86 554143000.0 330869.0 337089.0 403787.0 393166.0 405431.0 445431.0 412988.0 497487.0 369692.0 373938.0 True False 436078.4594972683 446046.42711532663 398432.5205502614 302527.6530541477 349143.90389847144 417578.12915494194 449743.1319362332 420611.81526398094 389233.16437882313 360846.5444378695 1.2084872814192966 1.2361111225553854 1.1041605543734492 0.8383831235669125 0.9675689272357352 1.1572180351773895 1.2463556569090823 1.1656251715510104 1.078666736258136 1.0 18.461025913636576 GGQGDPAVPAQQPADPST(ph)PER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GGQGDPAVPAQQPADPSTPER 21 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 GGQGDPAVPAQQPADPS(0.052)T(0.948)PER;GGQGDPAVPAQQPADPS(0.046)T(0.954)PER;GGQGDPAVPAQQPADPS(0.091)T(0.909)PER;GGQGDPAVPAQQPADPS(0.004)T(0.996)PER 282.18 4.719799999999999e-102 264732500.0 204933.0 264193.0 266088.0 231883.0 270950.0 216420.0 256467.0 216996.0 210196.0 177424.0 True False 239624.10928874943 290420.3350492899 272432.54706435965 218891.3472848287 217859.29253084966 205070.55421436403 232172.58909971424 211300.08492626646 213269.71884823687 209589.56671238842 1.1433017065089706 1.3856621758649963 1.2998383046337807 1.0443809332608849 1.0394567627968307 0.9784387526110704 1.107748790846615 1.0081612755859424 1.0175588517767136 1.0 17.677207376298178 -5.7745702628282265 7.698855949684429 1.0295971289875994 1.2876400513615502 0.7586306830783246 0.06409074910206425 0.061892200125100626 20.607374232571008 0.017233522063522203 0.02684517273574512 1.6804660276011951e-06 5.7745702628282265 0.2580429223739509 GGQGDPAVPAQQPADPST(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 6 GGQGDPAVPAQQPADPSTPER 21 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 GGQGDPAVPAQQPADPS(0.013)T(0.987)PER;GGQGDPAVPAQQPADPS(0.036)T(0.964)PER;GGQGDPAVPAQQPADPS(0.004)T(0.996)PER;GGQGDPAVPAQQPADPS(0.043)T(0.957)PER;GGQGDPAVPAQQPADPS(0.22)T(0.78)PER;GGQGDPAVPAQQPADPS(0.069)T(0.931)PER 282.18 4.719799999999999e-102 578468500.0 518742.0 650253.0 646900.0 582676.0 729452.0 660529.0 618508.0 657184.0 662936.0 594726.0 True False 511344.64395436685 648747.3791299239 593714.3791062132 625527.9367901556 686547.0675178099 632279.7144383043 650531.3178571129 687719.1678081432 588269.1666544375 697523.596677419 0.7330858000935077 0.9300723046792458 0.8511746153596951 0.896783907769992 0.984263573000405 0.9064635482585863 0.932629836403888 0.9859439466765307 0.8433681232528856 1.0 19.41188249744841 -4.0236318076883535 1.219605997820281 0.9299509547758608 1.3600988024450268e-42 0.5363800172692399 0.0525449426022082 6.2732708019341805 2.0693142620383385 0.01487820224708065 11.536479087891188 9.470397158274484e-05 4.0236318076883535 -0.9299509547758608 GGQGDPAVPAQQPADPST(ph)PERQS(ph)SPSGSEQLVR ddPTM_PC-9_AZD4547_30min_R2 1 GGQGDPAVPAQQPADPSTPERQSSPSGSEQLVR 33 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 2 GGQGDPAVPAQQPADPS(0.299)T(0.693)PERQS(0.333)S(0.333)PS(0.145)GS(0.198)EQLVR 69.197 7.5006e-05 54785000.0 39627.0 25550.0 48549.0 76241.0 69716.0 45541.0 31690.0 44835.0 34651.0 54109.0 True False 52227.56170719614 33808.53784251816 47905.20853864694 58664.815361707915 60037.136785756 42693.31407074314 34510.34860833543 37906.78095580505 36482.58111858147 52214.660379497785 1.0002470824784568 0.6474912906987549 0.917466630836443 1.1235314935562197 1.1498137946202123 0.8176499427640972 0.6609321665124916 0.725979651697385 0.698703790342117 1.0 15.67216731062239 -6.987845791613822 24.796828440334224 0.7472434479909735 0.9585802368293808 0.266313865246821 0.1543132324338783 279.1392623653781 569492.9929884129 0.057847067122953184 0.050979802072718045 1.0283813888408736e-07 6.987845791613822 0.21133678883840723 GGQGDPAVPAQQPADPST(ph)PERQS(ph)SPSGSEQLVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGQGDPAVPAQQPADPSTPERQSSPSGSEQLVR 33 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 2 GGQGDPAVPAQQPADPS(0.134)T(0.834)PERQS(0.441)S(0.441)PS(0.075)GS(0.075)EQLVR 54.24100000000001 0.004871100000000001 18802000.0 26762.0 16295.0 23898.0 35482.0 40135.0 41456.0 31705.0 48230.0 40035.0 25582.0 True False 31292.27802640631 17912.659910096685 24467.81895366969 33494.05857419607 32270.834861508178 39281.97438088289 28701.672875677777 46964.0136039091 40620.43613622117 30219.81409299941 1.0354887667444435 0.5927455362555077 0.8096614651027186 1.1083476050223338 1.067870065719031 1.2998747861252655 0.9497633833004512 1.554080162749531 1.3441656527473849 1.0 14.883207164872417 -6.030195175911488 1.4193733584223012 1.2431048231051705 0.7809474196949288 0.43479112062136205 0.19597858013565633 0.36460348298041706 1.486082169017461 0.06965579841302842 0.12068322907172756 9.32834982010158e-07 6.030195175911488 -0.4621574034102417 GGQGDPAVPAQQPADPST(ph)PERQSSPSGSEQLVR ddPTM_PC-9_AZD4547_30min_R2 2 GGQGDPAVPAQQPADPSTPERQSSPSGSEQLVR 33 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 GGQGDPAVPAQQPADPS(0.239)T(0.719)PERQS(0.02)S(0.007)PS(0.012)GS(0.004)EQLVR;GGQGDPAVPAQQPADPS(0.086)T(0.802)PERQS(0.015)S(0.018)PS(0.035)GS(0.043)EQLVR 97.40799999999999 8.9252e-16 25181000.0 38891.0 6051.5 43929.0 163175.0 102494.0 36783.3 25086.3 40661.0 23255.4 57149.0 True False 51257.52901694717 8007.529031467652 43346.47275730128 125557.5247786191 88264.47727522062 34483.2344361864 27318.932101397433 34377.776746827 24484.632967159934 55148.23090480181 0.929450105216052 0.1452001070585644 0.7859993339065943 2.27672806033179 1.600495171415106 0.62528269484677 0.4953727735810062 0.6233704360557049 0.443978574932456 1.0 15.751026986022394 -6.882862576213587 11.648112794422504 0.6024071953614324 1.1343492291625208 0.1837413639304084 0.534712699871006 0.790612331108874 76.69257282059324 0.2137652673916479 0.18854275113755087 1.3095962529353203e-07 6.882862576213587 0.5319420338010884 GGQGDPAVPTQQPADPS(ph)TPEQQNSPSGSEQFVR ddPTM_PC-9_AZD4547_30min_R2 3 GGQGDPAVPTQQPADPSTPEQQNSPSGSEQFVR 33 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 GGQGDPAVPTQQPADPS(0.5)T(0.5)PEQQNSPSGSEQFVR;GGQGDPAVPT(0.175)QQPADPS(0.802)T(0.023)PEQQNSPSGSEQFVR;GGQGDPAVPTQQPADPS(0.5)T(0.5)PEQQNSPSGSEQFVR 150.86 4.622e-24 30105100.0 218251.0 185395.0 273378.0 379519.0 315163.0 277629.0 237194.0 322216.0 232612.0 268675.0 True False 287650.2780971884 245320.30815317613 269752.8290979881 292026.7580600995 271408.0575593731 260268.81474158156 258303.8064943363 272424.920987079 244907.39543319 259268.77002830515 1.1094675153732736 0.9462007635026531 1.0404370301465091 1.1263476045657872 1.0468212485820898 1.0038571738245499 0.9962781343319387 1.0507432922111581 0.9446081585778832 1.0 17.98408891264217 -6.752517060865723 5.857563597282283 1.0018775350149682 1.0514179321837216 0.22340556539661627 0.050876694267233014 0.30010788475071287 35.54554775831843 0.017788082734630412 0.01688569410040697 1.768002761981458e-07 6.752517060865723 0.04954039716875336 GGQGDPAVPTQQPADPS(ph)TPEQQNSPSGSEQFVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGQGDPAVPTQQPADPSTPEQQNSPSGSEQFVR 33 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 GGQGDPAVPTQQPADPS(0.5)T(0.5)PEQQNSPSGSEQFVR 136.86 6.926e-24 8073700.0 81741.0 70730.0 89481.0 94948.0 102760.0 97774.0 99882.0 92166.0 91711.0 75721.0 True False 95578.13684165923 77751.60696171467 91614.56639858238 89628.37138556922 82624.9156688322 92646.55931871009 90420.4538769419 89746.74015794926 93052.09987483415 89448.61789289382 1.068525585896754 0.8692320663334877 1.0242144435175295 1.0020095726117382 0.9237137209628845 1.0357517142371668 1.0108647400814148 1.0033328884456596 1.0402854964875496 1.0 16.448771570328894 -6.7994876646604885 24.99909451782268 1.017806389002633 0.9754744013158984 0.13084086747875767 0.05206431427949304 331.4036950078518 217741.98796356306 0.01741248815650989 0.015356679754428372 1.5867639874370303e-07 6.7994876646604885 -0.04233198768673463 GGQGDPAVPTQQPADPS(ph)TPEQQNSPSGSEQFVR ddPTM_PC-9_Lapatinib_30min_R1 1 GGQGDPAVPTQQPADPSTPEQQNSPSGSEQFVR 33 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 GGQGDPAVPTQQPADPS(0.5)T(0.5)PEQQNSPSGSEQFVR 146.03 4.8041000000000005e-22 14107000.0 118810.0 114240.0 133430.0 115290.0 127390.0 130430.0 111890.0 114590.0 138080.0 102300.0 True False 117115.74761291461 113975.48429888471 122459.90045469471 123768.81119616557 119897.17065837618 124851.8129471803 117683.11671802521 119914.26973136164 122527.97635313937 119982.4186938186 0.9761075738253001 0.9499348782902693 1.0206487066009093 1.0315578944279278 0.9992894956080194 1.0405842314763452 0.980836342517307 0.9994320087626265 1.0212160888822948 1.0 16.87246349425805 -5.264514950601655 24.975575299080738 1.011871224994155 0.9630212243343139 0.5472435389127075 0.017708760266208302 177.3330296318705 1440066.7996587015 0.004579776144258438 0.010256747985240981 5.4385740908916146e-06 5.264514950601655 -0.04885000065984113 GGQGDPAVPTQQPADPST(ph)PEQQNS(ph)PSGSEQFVR ddPTM_PC-9_AZD4547_30min_R2 1 GGQGDPAVPTQQPADPSTPEQQNSPSGSEQFVR 33 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 2 GGQGDPAVPT(0.001)QQPADPS(0.457)T(0.542)PEQQNS(0.828)PS(0.156)GS(0.015)EQFVR 135.16 4.0204e-21 6963400.0 79079.0 75009.0 106090.0 126850.0 118040.0 108120.0 89648.0 125830.0 81066.0 108750.0 True False 104224.47705461827 99254.19236905845 104683.1772820254 97606.69231296366 101652.18351871357 101359.2393080685 97626.49832881211 106385.86478574654 85350.98326048096 104942.69560092367 0.9931560882613817 0.9457941955913017 0.9975270473336689 0.930095151015966 0.9686446773320625 0.9658532090076821 0.9302838827398373 1.013751973651515 0.8133103764082246 1.0 16.67924222765994 -8.226212067595009 24.99985825052819 0.9066547998354104 0.965783888213361 0.19730279444773668 0.049422703828471 783.1295335604664 555767.4160276911 0.029945149060313567 0.011316860352743449 5.9400203440588245e-09 8.226212067595009 0.05912908837795061 GGQGDPAVPTQQPADPST(ph)PEQQNS(ph)PSGSEQFVR ddPTM_PC-9_Lapatinib_30min_R1 2 GGQGDPAVPTQQPADPSTPEQQNSPSGSEQFVR 33 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 2 GGQGDPAVPT(0.015)QQPADPS(0.459)T(0.527)PEQQNS(0.849)PS(0.141)GS(0.01)EQFVR;GGQGDPAVPT(0.008)QQPADPS(0.458)T(0.535)PEQQNS(0.879)PS(0.112)GS(0.009)EQFVR 132.93 2.9197e-23 17189300.0 122715.0 130021.0 150600.0 124333.0 138647.0 134018.0 109705.0 119048.0 135200.0 106122.0 True False 120965.0615968254 129719.94436296614 138218.24933281148 133476.86358272913 130492.05605048986 128286.36255121673 115384.98810931234 124579.40468609118 119972.35228088369 124465.04630132359 0.9718797782308706 1.0422198698976153 1.1104985169747343 1.072404402273618 1.0484233118314614 1.0307019228566543 0.9270473240332159 1.0009187991983768 0.9639039701992854 1.0 16.92538111947799 -7.066951094562683 5.882566851923857 0.9731289023406642 1.052253249662494 0.4802808175244273 0.037540626210930836 0.20019711300285992 13.228764313154263 0.015009346781717156 0.011696150826439449 8.57134360780045e-08 7.066951094562683 0.07912434732182971 GGQGDPAVPTQQPADPST(ph)PEQQNSPSGSEQFVR ddPTM_PC-9_Lapatinib_30min_R1 1 GGQGDPAVPTQQPADPSTPEQQNSPSGSEQFVR 33 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 GGQGDPAVPT(0.01)QQPADPS(0.228)T(0.762)PEQQNSPSGSEQFVR 104.24 2.2704999999999998e-20 12813000.0 65409.0 67676.0 79437.0 65235.0 77761.0 71093.0 66747.0 66306.0 81054.0 62766.0 True False 64476.25566545849 67519.30038000116 72905.99649568758 70032.5995175806 73187.2508640081 68052.51811587738 70202.83306442066 69386.81882195381 71924.84498354097 73615.01946956216 0.8758573471833109 0.9171946277609637 0.99036850117023 0.9513357467294729 0.9941891123763008 0.9244379558170908 0.9536482306229321 0.9425633426700838 0.9770403580926847 1.0 16.16771252495701 -5.0047316006636935 3.7837294445664593 0.9630095596386555 0.8799767256877675 0.6078452528364624 0.023464279316486855 0.14175946265835754 4.442726813083691 0.0058446091791269986 0.024115030537762573 9.89164221461759e-06 5.0047316006636935 -0.08303283395088801 GGQGDPAVPTQQPADPSTPEQQNS(ph)PSGSEQFVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGQGDPAVPTQQPADPSTPEQQNSPSGSEQFVR 33 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 GGQGDPAVPTQQPADPS(0.016)T(0.056)PEQQNS(0.71)PS(0.199)GS(0.019)EQFVR;GGQGDPAVPT(0.001)QQPADPS(0.007)T(0.007)PEQQNS(0.737)PS(0.215)GS(0.033)EQFVR 125.14 8.417499999999999e-23 15245600.0 90946.0 78246.0 102120.0 98310.0 115704.0 105970.0 111242.0 107220.0 96014.0 78621.0 True False 106341.36153462164 86013.74577020101 104554.92809225679 92802.00942532014 93032.63178811384 100412.74665047672 100704.3524376644 104405.58860898062 97418.02310935788 92874.36493650656 1.1450023007675127 0.9261301095195019 1.1257673542503965 0.9992209312953484 1.0017040961918338 1.081167518282615 1.0843073059666228 1.1241593811204778 1.0489226297908747 1.0 16.502992820263024 -6.793310531459132 24.938152175655517 1.076508600981577 1.035810690835767 0.03381873907481869 0.0659655867385922 502.6743322639648 393323.29659543885 0.02177770740825501 0.019207458699022413 1.6094943947398542e-07 6.793310531459132 -0.040697910145810035 GGQGDPAVPTQQPADPSTPEQQNS(ph)PSGSEQFVR ddPTM_PC-9_Lapatinib_30min_R1 1 GGQGDPAVPTQQPADPSTPEQQNSPSGSEQFVR 33 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 GGQGDPAVPT(0.001)QQPADPS(0.006)T(0.006)PEQQNS(0.746)PS(0.175)GS(0.067)EQFVR 95.454 4.9632e-08 0.0 15735.0 19405.0 20304.0 20095.0 21015.0 20549.0 17847.0 16485.0 21317.0 18264.0 True False 15510.616014554398 19360.068914739648 18634.68349570653 21572.853334954878 19778.939017079665 19670.167172058627 18771.03033395834 17250.95328145125 18916.05498203845 21420.908064749743 0.7240876982278205 0.9037931004707773 0.8699296705526585 1.0070933160137676 0.923347364980661 0.9182695295923455 0.8762947993249622 0.8053324924091069 0.883065037432597 1.0 14.386732018962695 -4.761306959194013 8.626774945457973 0.9051504688713237 0.7224982953501533 0.48735440484084835 0.0569355860598243 0.08033167785908452 69.10995757059379 0.014752833397247162 0.08526583259010481 1.7325789786431226e-05 4.761306959194013 -0.18265217352117036 GGQVSLTVHGTQQVHS(ph)PPEQSPVQANSSSSK ddPTM_PC-9_AZD4547_30min_R2 2 GGQVSLTVHGTQQVHSPPEQSPVQANSSSSK 31 0 P22670 P22670 RFX1 MHC class II regulatory factor RFX1 1 GGQVS(0.002)LT(0.01)VHGT(0.045)QQVHS(0.898)PPEQS(0.045)PVQANSSSSK;GGQVSLTVHGTQQVHS(1)PPEQSPVQANSSSSK 127.25 7.4053e-16 23797000.0 5048.3 5409.24 30526.2 68117.0 43582.0 35672.0 16976.2 48239.0 21768.6 37951.9 True False 6653.55438883686 7157.671046546494 30121.402642535253 52413.67804715917 37531.391580079464 33441.424200864014 18487.048912742946 40784.77097194334 22919.243754522297 36623.21553265934 0.18167586576070704 0.19544081376916578 0.8224674487054259 1.4311599155027344 1.024797823845103 0.913120918370537 0.5047904353525927 1.1136316235141304 0.625811890659456 1.0 15.160470845435137 -5.295024893901024 4.504207272377401 0.9448539124908139 0.17791889298818303 0.6069128760986648 0.2397578657241366 0.12769860643088177 6.31017230275296 0.065744062640196 0.15473124771346672 5.069616482352024e-06 5.295024893901024 -0.7669350195026308 GGQVSLTVHGTQQVHS(ph)PPEQSPVQANSSSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGQVSLTVHGTQQVHSPPEQSPVQANSSSSK 31 0 P22670 P22670 RFX1 MHC class II regulatory factor RFX1 1 GGQVSLTVHGT(0.002)QQVHS(0.743)PPEQS(0.254)PVQANS(0.001)SSSK;GGQVSLTVHGT(0.001)QQVHS(0.992)PPEQS(0.006)PVQANSSSSK 80.554 5.299800000000001e-07 11128400.0 8920.8 16927.8 60074.0 64321.0 86288.0 84681.0 56175.0 50456.0 66249.0 40656.0 True False 10430.915246168646 18608.28011206718 61506.39199191367 60717.302901495554 69380.48582359077 80240.1792876192 50853.69732821948 49131.583462551054 67217.7662942056 48026.61096728107 0.21719032503198865 0.38745769766566246 1.2806731675032395 1.2642429203022514 1.4446258943996149 1.670744149369277 1.058864998050027 1.023007505068862 1.39959420288887 1.0 15.551546386892152 -5.227976880441886 4.179594585117636 1.2853145574023679 0.2610423172013802 0.7916676551200257 0.19854366990040792 0.09104380419567148 3.6720205391873675 0.05455338846853189 0.15075230099055872 5.9159312664934205e-06 5.227976880441886 -1.0242722402009876 down GGQVSLTVHGTQQVHS(ph)PPEQSPVQANSSSSK ddPTM_PC-9_Lapatinib_30min_R1 1 GGQVSLTVHGTQQVHSPPEQSPVQANSSSSK 31 0 P22670 P22670 RFX1 MHC class II regulatory factor RFX1 1 GGQVSLTVHGT(0.001)QQVHS(0.992)PPEQS(0.007)PVQANSSSSK 85.291 6.7276999999999994e-09 6039000.0 16145.0 7744.0 36828.0 13713.0 22056.0 29974.0 12254.0 17688.0 37869.0 11353.0 True False 15914.769339369617 7726.069243789942 33800.1440001911 14721.499765226992 20758.709443764412 28692.08189280671 12888.452160717517 18509.849053218673 33603.794441751365 13315.35092307839 1.1952196702368447 0.5802377487775399 2.538434337589115 1.1056035886903621 1.5590058094364654 2.1548122958650016 0.9679393532452109 1.3901134983334982 2.523688232918346 1.0 13.700802830502294 -5.224414825826658 24.982668341093316 1.6391527988857884 0.8877286362757013 0.22386556768453092 0.5708134697250364 839.2911663001007 566317.137063074 0.13835959612833615 0.36604461993196696 5.9646528760239435e-06 5.224414825826658 -0.751424162610087 GGRPGGFPDHPHR ddPTM_PC-9_AZD4547_30min_R2 2 GGRPGGFPDHPHR 13 1 O00625 O00625 PIR Pirin 0 ; 72.34 0.010731000000000001 8910000.0 21395.2 23912.0 36308.0 50217.0 35136.0 33959.0 31579.0 39523.0 31359.0 31000.0 False True 28198.42855219428 31641.086375353963 35826.53219677425 38640.24649491598 30257.972891507314 31835.538361660158 34389.46982337092 33415.62849818851 33016.57271933267 29914.699435665632 0.9426278413004833 1.0577103220910204 1.1976230038286886 1.2916809202116655 1.0114750762106075 1.0642105373689437 1.1495843338599707 1.11703039403929 1.1036906050263986 1.0 14.868566947310727 -9.448826825150144 15.57217091908426 0.9999936598058436 1.1087121673946987 0.10099988338304688 0.09206969258834469 0.0 0.0 0.09367865465023818 0.022720411058158304 3.5577315477271217e-10 9.448826825150144 0.10871850758885504 GGRPGGFPDHPHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGRPGGFPDHPHR 13 1 O00625 O00625 PIR Pirin 0 ; 76.52199999999999 0.007725 4517300.0 21942.8 19566.1 25830.0 24800.7 35133.0 22828.9 23113.0 22647.5 27231.1 21525.0 False True 25657.282649945028 21508.493100149917 26445.885160820515 23411.19718395425 28248.940854350752 21631.71229601837 20923.56931637092 22053.02712200977 27629.303321320163 25427.312108193757 1.0090442332548852 0.8458815075943072 1.0400582274796766 0.9207106549185814 1.1109684238015762 0.8507274462977042 0.8228777476494835 0.8672968274496993 1.086599448803589 1.0 14.634091344010367 GGRPGGFPDHPHR ddPTM_PC-9_Lapatinib_30min_R1 1 GGRPGGFPDHPHR 13 1 O00625 O00625 PIR Pirin 0 55.98 0.033884 2741800.0 10879.0 11583.0 11547.0 9839.6 11505.0 11842.0 7532.4 9527.3 12383.0 8991.8 False True 10723.86346503574 11556.180275157392 10597.650232708993 10563.237007943379 10828.298519700278 11335.545265050285 7922.390815683745 9969.973139118618 10988.29614122917 10546.020649179622 1.016863499681271 1.0957858570148307 1.0048956459736675 1.0016324981086677 1.0267662922263114 1.0748646946687024 0.7512208708125401 0.9453777373263711 1.041937666041262 1.0 13.364411106189227 GGRS(ph)PDEVTLTSIVPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GGRSPDEVTLTSIVPTR 17 1 A0A0C4DGG1;Q9UKS6;H0YDM6 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 1 GGRS(1)PDEVTLTSIVPTR;GGRS(1)PDEVTLTSIVPTR;GGRS(1)PDEVTLTSIVPTR;GGRS(1)PDEVTLTSIVPTR 115.38 7.2684e-05 47747900.0 57546.4 46959.7 55491.8 52010.5 64088.5 62554.7 54886.5 60002.5 59249.9 52907.9 True False 67287.86892679124 51621.54867015451 56814.93496582344 49096.520305316066 51530.81848814667 59274.2214107443 49687.25337615167 58427.49795290385 60116.31769770181 62499.68345129408 1.0766113556275623 0.8259489619716732 0.9090435635581938 0.7855483035138398 0.8244972717070571 0.948392345969826 0.7950000805183738 0.9348447020285522 0.9618659548020012 1.0 15.931561262373698 -7.990645059049768 24.0846914619185 0.9700737997829305 0.8756571610316508 0.1928577113800778 0.08213647403955364 193.6105677318406 498458.2541661629 0.043670308433234384 0.020928189834032752 1.0217742199671627e-08 7.990645059049768 -0.0944166387512797 GGRS(ph)PDEVTLTSIVPTR ddPTM_PC-9_Lapatinib_30min_R1 2 GGRSPDEVTLTSIVPTR 17 1 A0A0C4DGG1;Q9UKS6;H0YDM6 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 1 GGRS(1)PDEVTLTSIVPTR;GGRS(1)PDEVTLTSIVPTR 163.44 0.00015031 16767900.0 47773.1 41315.0 50401.0 39783.0 36868.2 43706.0 40102.8 34387.1 52435.0 34716.4 True False 47091.8468334864 41219.33765588601 46257.22433348623 42708.77453219755 34699.684961670064 41836.7962636622 42179.12675949259 35984.85020228039 46529.21813497141 40717.08348330477 1.1565623763989745 1.0123352197557858 1.1360642849690619 1.0489153661929012 0.8522144022397375 1.0274998277029481 1.0359073674023656 0.8837776953507798 1.1427443754425533 1.0 15.313346606118667 -6.006581000988631 24.76088512120826 0.9852157123002372 1.0926833962645233 0.2620966169523403 0.08353964329949208 359.04992366264844 1350929.903848373 0.022699457996386674 0.032339558427285586 9.849609189664108e-07 6.006581000988631 0.10746768396428608 GGS(ph)DGYGSGR ddPTM_PC-9_AZD4547_30min_R2 2 GGSDGYGSGR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 GGS(0.993)DGY(0.001)GS(0.006)GR;GGS(0.995)DGY(0.001)GS(0.004)GR 112.64 0.0014215 36906000.0 70809.0 63032.0 78168.0 125847.0 112549.0 91513.0 78109.0 85482.0 92096.0 103619.0 True False 93324.78908130464 83405.86134205876 77131.44124593606 96834.91846676804 96923.51408715436 85790.67764335229 85060.54968281703 72272.72108094407 96964.00654228951 99991.33034916877 0.9333288071617346 0.8341309296596644 0.7713812885236531 0.9684331444398372 0.9693191774596694 0.8579811604043277 0.8506792477486438 0.7227898741677745 0.9697241371196096 1.0 16.60951539239204 -5.818812140567275 0.00876321780082481 1.7389600299533021 1.5336998113516716e-06 0.06425268736480105 0.08676427600526905 24650.17997491129 49.61420579167401 4713.418637553649 5134.849270552138 1.5177067282483009e-06 5.818812140567275 -1.7389584962534907 GGS(ph)DGYGSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGSDGYGSGR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 GGS(0.523)DGY(0.069)GS(0.408)GR;GGS(0.663)DGY(0.083)GS(0.254)GR 100.09 0.0041234999999999996 31230000.0 86247.0 112747.0 128282.0 131332.0 145357.0 133746.0 109703.0 114403.0 136257.0 117365.0 True False 100846.91364410217 123939.7770410354 131340.72939219396 123973.8938240886 116875.33930395512 126732.12431362318 99311.13765905939 111400.04246999804 138249.50085208134 138642.34543917136 0.7273889757465785 0.8939532626084529 0.9473348779274586 0.8941993402620381 0.8429988610891871 0.9140939149015354 0.7163117252847663 0.8035066207017845 0.9971664891715037 1.0 17.081008440602922 -8.272850521913455 23.684924073554402 0.9985833415121459 0.8476084915625433 0.42557379979454735 0.07235055192293621 424.9534077456887 882013.1269471337 0.07047862275080786 0.018929612965198215 5.335184934934442e-09 8.272850521913455 -0.15097484994960264 GGS(ph)DGYGSGR ddPTM_PC-9_Lapatinib_30min_R1 2 GGSDGYGSGR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 GGS(1)DGYGSGR;GGS(0.993)DGY(0.005)GS(0.002)GR 118.77 0.00084579 32749000.0 103281.0 115644.0 140054.0 100716.0 117841.0 109607.0 101786.0 110725.0 125061.0 96217.0 True False 101808.19400058436 115376.23342314627 128539.300744074 108122.9906187268 110909.8240643199 104919.36411639635 107055.9810372771 115869.68772148565 110975.31322928687 112847.98024890656 0.902171166697251 1.022404062249614 1.1390483060534837 0.9581296039170755 0.9828250697946768 0.9297407351463249 0.9486743209860365 1.026776797120464 0.9834054006505992 1.0 16.78402107186809 -4.752611606402596 24.67303608235334 0.9986939912867278 0.9021709480899273 0.21703064980073172 0.055171919062004464 504.83907093598833 1410866.6763141647 0.014792685436583056 0.17051095918573245 1.7676179111862825e-05 4.752611606402596 -0.0965230431968005 GGS(ph)FGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGSFGGR 7 0 P51991;P51991-2;H7C1J8 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 1 GGS(1)FGGR 69.628 0.046066 3844200.0 17397.0 24293.0 29701.0 28189.0 40809.0 34438.0 28124.0 31253.0 33601.0 28283.0 True False 20341.968493587563 26704.648493156103 30409.18448166977 26609.661719971053 32812.76939985768 32632.010655365833 25459.89111987263 30432.64186529068 34092.35105815332 33410.48401189519 0.608849859413745 0.7992894830152236 0.9101689299335842 0.7964464600541905 0.9821099684810102 0.9766997282573878 0.7620329927219284 0.9108710264255883 1.0204087748628652 1.0 15.028013262446905 -4.196187220963209 0.9333087496409294 0.9214080687618211 9.366654491199905e-18 0.6027116329713378 0.0788715184164109 3.9687884093806467 1.2694790862174838 0.0267294196881932 4.813542365609339 6.365210624891988e-05 4.196187220963209 -0.9214080687618211 GGS(ph)GGGGEGIQDR ddPTM_PC-9_AZD4547_30min_R2 2 GGSGGGGEGIQDR 13 0 O43823 O43823 AKAP8 A-kinase anchor protein 8 1 GGS(1)GGGGEGIQDR;GGS(1)GGGGEGIQDR 122.78 0.00017656 12039400.0 18082.4 12024.4 15866.1 27717.0 27918.0 23341.0 18594.3 25993.0 18025.5 22586.0 True False 23832.22706271489 15911.052150042078 15655.705147274424 21327.273873381233 24042.067599758127 21881.48358018521 20249.156678067873 21976.37910971875 18978.291130212398 21795.271014643364 1.093458624428344 0.7300231384758686 0.7183074317706803 0.9785275833024649 1.1030864256565212 1.003955562905546 0.9290619357044599 1.0083095133322135 0.8707527021555111 1.0 14.411727522633472 -5.877582805751245 9.582464407217646 0.989381006492757 0.8358212272884042 0.24254233011349668 0.11077863497246485 0.37067183209915894 29.39771435875101 0.031348782109371684 0.04657267053698724 1.3256143423711618e-06 5.877582805751245 -0.1535597792043527 GGS(ph)GGGGEGIQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGSGGGGEGIQDR 13 0 O43823 O43823 AKAP8 A-kinase anchor protein 8 1 GGS(1)GGGGEGIQDR;GGS(1)GGGGEGIQDR 88.78 0.0064329999999999995 9419800.0 19054.3 19859.4 24090.0 20109.1 25053.0 18094.5 15905.2 18644.199999999997 22275.9 20114.8 True False 22279.816650420522 21830.909985797745 24664.396961833765 18982.45232158182 20144.04449446531 17145.592566453244 14398.544312323937 18154.8095051628 22601.64289563754 23761.45401133082 0.9376453410551489 0.9187531190384022 1.0380003239731193 0.7988758731906683 0.847761441065832 0.7215716916261624 0.6059622574215318 0.7640445528504084 0.9511893878573163 1.0 14.53633549981077 -5.782905363685985 22.41750340994181 0.7919812684157754 0.9601948095320654 0.27402958180372683 0.10972630488733619 83.351161880279 87045.40189253606 0.03170963316124219 0.04711354842355782 1.6485215787028509e-06 5.782905363685985 0.16821354111628994 GGS(ph)GGGGEGIQDR ddPTM_PC-9_Lapatinib_30min_R1 1 GGSGGGGEGIQDR 13 0 O43823 O43823 AKAP8 A-kinase anchor protein 8 1 GGS(1)GGGGEGIQDR 98.25299999999999 0.0028057 5104300.0 6747.1 5903.0 6718.6 8066.6 9339.7 7602.2 4960.2 5888.8 7772.6 3147.3 True False 6650.885116733399 5889.331966179242 6166.222642545995 8659.84467338876 8790.357208556688 7277.071627593753 5217.0148855550015 6162.4151461213305 6897.167938893465 3691.306611486359 1.8017698925463472 1.5954599782779397 1.6704715407163304 2.3460106636608398 2.381367394733195 1.9714080658998774 1.4133247206615258 1.6694400641077993 1.8684895796603087 1.0 11.84991586199066 -9.338451616756691 0.5463818153502845 0.9493426743944013 1.920841303244817 0.4482987022715106 0.2902876659928455 3.314822681776866 1.3736132812635604 0.7482775607154345 0.15250626671280892 4.587207474405305e-10 9.338451616756691 0.9714986288504157 GGS(ph)GGGGGGGGGGYNR ddPTM_PC-9_AZD4547_30min_R2 2 GGSGGGGGGGGGGYNR 16 0 H3BPE7;P35637-2;P35637;H3BNZ4 H3BPE7 FUS RNA-binding protein FUS 1 GGS(1)GGGGGGGGGGYNR;GGS(0.994)GGGGGGGGGGY(0.006)NR 125.36 3.2051e-05 5635700.0 2961.25 2740.06 5198.299999999999 6934.6 5848.2 4549.1 4964.1 6888.4 4654.9 5077.5 True False 3902.865902173634 3625.7308102062743 5129.367145491116 5335.935108501987 5036.278377280083 4264.644057864725 5405.895283264053 5823.956059684784 4900.948510833304 4899.738270470722 0.7965457921895658 0.7399845889845761 1.0468655390032362 1.0890245180360134 1.0278668164036942 0.8703820127631058 1.1033028673886096 1.1886259506521095 1.0002470010224578 1.0 12.258488971445281 -5.264831202974536 24.462086541982966 1.0449338057479822 0.768265170421998 0.6555091899780496 0.07897927634447799 121.58621292374528 876899.0591036571 0.02183001948851791 0.048620112480241895 5.434615173731656e-06 5.264831202974536 -0.2766686353259842 GGS(ph)GGGGGGGGGGYNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GGSGGGGGGGGGGYNR 16 0 H3BPE7;P35637-2;P35637;H3BNZ4 H3BPE7 FUS RNA-binding protein FUS 1 GGS(1)GGGGGGGGGGYNR;GGS(1)GGGGGGGGGGYNR;GGS(0.998)GGGGGGGGGGY(0.002)NR;GGS(1)GGGGGGGGGGYNR 99.069 0.001964 10330400.0 6488.0199999999995 5372.83 13182.0 10665.1 11049.6 10121.5 7606.870000000001 8847.47 8671.4 6798.17 True False 7586.313641763866 5906.209054603547 13496.308873013386 10067.569023720716 8884.51020021729 9590.710722117583 6886.292204630407 8615.23328716934 8798.20282032293 8030.624406715893 0.9446729491444704 0.735460750681388 1.680605167105888 1.2536471031195726 1.106328692546909 1.1942671249942922 0.8575039568369679 1.0727974377639362 1.095581411199498 1.0 12.971296450916565 -7.22077829831295 24.642804198333064 1.0125369225070762 1.1600448872032152 0.08506573181928467 0.23349044553794515 1244.8536881094735 754449.0128049884 0.0946202341566148 0.07329158591277886 6.014807072061808e-08 7.22077829831295 0.14750796469613903 GGS(ph)GGGGGGGGGGYNR ddPTM_PC-9_Lapatinib_30min_R1 3 GGSGGGGGGGGGGYNR 16 0 H3BPE7;P35637-2;P35637;H3BNZ4 H3BPE7 FUS RNA-binding protein FUS 1 GGS(1)GGGGGGGGGGYNR;GGS(1)GGGGGGGGGGYNR;GGS(1)GGGGGGGGGGYNR 118.08 0.0001317 9535200.0 3701.92 3730.72 3608.62 2263.1 4438.48 3052.1399999999994 5258.9 4267.22 4629.67 2422.24 True False 3649.1299419510165 3722.0817470547545 3311.9331932760288 2429.535923480289 4177.417332787425 2921.6070870858434 5531.180110004674 4465.490619452497 4108.227812013601 2840.9209565680803 1.2844883746287956 1.3101673027718248 1.1657956148406696 0.8551930731699213 1.4704447595169536 1.0284013993177883 1.946967266800168 1.5718461328987299 1.4460901499267569 1.0 11.472142976395931 -7.230762348019597 24.996324363020488 1.5388799747125597 1.1884123777896254 0.23295614002435128 0.2659644805701302 859.7844445696475 700572.3279388279 0.09803828223888077 0.07593214271085426 5.878109228497802e-08 7.230762348019597 -0.3504675969229343 GGS(ph)GSGPTIEEVD ddPTM_PC-9_AZD4547_30min_R2 1 GGSGSGPTIEEVD 13 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 1 GGS(0.895)GS(0.105)GPTIEEVD 150.09 0.00012557 7637300.0 17463.0 26525.0 34675.0 39842.0 32197.0 28981.0 19667.0 31458.0 29469.0 32256.0 True False 23015.87074703525 35098.68752535396 34215.186843757496 30657.042452763828 27727.002310674543 27168.813488597225 21417.324899972624 26596.888932925507 31026.671177844142 31126.727257962273 0.7394246930071245 1.1276060998791853 1.099222110959487 0.984910562510927 0.890777950437495 0.8728451681873298 0.6880686402549446 0.8544711017160332 0.9967855252083229 1.0 14.925866275761681 -6.289310523798163 3.3062638186487736 0.8632942789436946 1.0079732276519466 0.12354116499119783 0.12740788905892833 0.408672117324527 9.267871852810188 0.041264509806273074 0.05010329009911877 5.136762378997393e-07 6.289310523798163 0.14467894870825204 GGS(ph)GSGPTIEEVD ddPTM_PC-9_Lapatinib_30min_R1 2 GGSGSGPTIEEVD 13 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 1 GGS(0.996)GS(0.004)GPTIEEVD;GGS(0.499)GS(0.499)GPT(0.003)IEEVD 171.67 0.00021953 15013400.0 83354.0 74646.0 79120.0 66578.0 73118.0 83503.0 67381.0 66929.0 81849.0 62674.0 True False 82165.35667474865 74473.1617732364 72615.05901203224 71474.36821769715 68817.34299551888 79931.77134500032 70869.6584822349 70038.76567632705 72630.30371181983 73507.11739214436 1.1177877679029975 1.0131421883399183 0.9878643264521833 0.972346226507524 0.9361997237409466 1.0874017942858765 0.9641196797877518 0.9528161103459627 0.9880717172509035 1.0 16.165596326494637 -4.721209621758469 2.3778186951515647 0.9850474003136852 1.1629423758655222 0.5128918887566083 0.03840856592967388 0.5888801225911539 3.5264283294205474 0.010134072892698241 0.23255368445967148 1.900160904202597e-05 4.721209621758469 0.17789497555183698 GGS(ph)GSHNWGTVK ddPTM_PC-9_Lapatinib_30min_R1 1 GGSGSHNWGTVK 12 0 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 GGS(0.986)GS(0.013)HNWGTVK 109.95 0.0012506 2925700.0 27454.0 31159.0 24016.0 28238.0 23127.0 23245.0 23464.0 20939.0 25670.0 19727.0 True False 27062.500925553013 31086.85324990326 22041.497184440912 30314.716719206583 21766.715329431427 22250.865536741592 24678.851109766252 21911.902381577675 22778.774282916318 23136.785665424784 1.1696741853815393 1.34361158457542 0.9526603004919282 1.3102389051608139 0.9407838947118412 0.9617094551726303 1.066649942936797 0.947059055585342 0.98452631287312 1.0 14.497900827976661 -6.275801754489472 24.991060334411216 0.9838802148492657 1.1874876330565312 0.5012839932534552 0.10281998939111271 666.4612143430521 1159664.7317537253 0.03055364891232367 0.03480309296536664 5.299052783466012e-07 6.275801754489472 0.20360741820726547 GGS(ph)GSVLQDEEVLASLER ddPTM_PC-9_AZD4547_30min_R2 1 GGSGSVLQDEEVLASLER 18 0 A0A0D9SG79;Q9NZ09-2;Q9NZ09;Q9NZ09-3;Q9NZ09-4 A0A0D9SG79 UBAP1 Ubiquitin-associated protein 1 1 GGS(0.741)GS(0.259)VLQDEEVLASLER 89.46 0.010254000000000001 0.0 844.99 861.34 920.54 2782.7 939.67 799.1 766.45 824.82 490.7 405.29 True False 1113.6792431161489 1139.751310578261 908.3330381298495 2141.1915072864294 809.2130403848664 749.1321506758932 834.6625651896077 697.3630214780219 516.6374002160954 391.10092046067496 2.8475495322392854 2.9142128053182694 2.3225029413378278 5.474780025483795 2.06906452542147 1.9154446115685329 2.134136028640548 1.7830769118533472 1.3209823173199182 1.0 8.611397121249542 -6.499257487266425 24.992376726274394 1.7423686709188237 3.3411060979063785 0.4993009445087476 0.8324496737839704 695.9119602095932 736307.7274870091 0.2587625187747806 0.29162405162294297 3.1676888267507374e-07 6.499257487266425 1.5987374269875547 GGS(ph)PAPLPAKVDEATSGLIR ddPTM_PC-9_AZD4547_30min_R2 2 GGSPAPLPAKVDEATSGLIR 20 1 A0A087WWH3;Q9NZM4-2;Q9NZM4 A0A087WWH3 GLTSCR1 Glioma tumor suppressor candidate region gene 1 protein 1 GGS(1)PAPLPAKVDEATSGLIR;GGS(1)PAPLPAKVDEATSGLIR 61.038999999999994 0.0059091000000000005 14988100.0 27679.0 25822.9 46500.0 71402.0 57235.0 45287.0 33976.0 46415.0 32746.0 39807.0 True False 36480.34624103468 34169.647430667785 45883.37961743973 54941.37204990318 49288.908198013996 42455.196730896205 36999.79817976662 39242.628260593076 34476.88670771604 38413.369046307824 0.9496783840297147 0.8895248784212555 1.1944638222730921 1.4302669464808107 1.2831185970331207 1.1052192969514312 0.9632010703139023 1.0215877762058716 0.8975231166564354 1.0 15.229320880602732 -7.1650776391441156 4.171334982309549 0.9721835285893576 1.1561004742272205 0.2483443006870708 0.14694504465351993 0.39111137741520435 12.001476725186544 0.06788333353375531 0.051437494345845464 6.837893948208793e-08 7.1650776391441156 0.18391694563786287 GGS(ph)PAPLPAKVDEATSGLIR ddPTM_PC-9_Lapatinib_30min_R1 2 GGSPAPLPAKVDEATSGLIR 20 1 A0A087WWH3;Q9NZM4-2;Q9NZM4 A0A087WWH3 GLTSCR1 Glioma tumor suppressor candidate region gene 1 protein 1 GGS(1)PAPLPAKVDEATSGLIR;GGS(1)PAPLPAKVDEATSGLIR 81.329 0.00060007 12222400.0 69762.0 42743.0 46944.0 40842.0 35663.0 40997.0 26500.0 26169.0 52339.0 26958.0 True False 68767.18108721611 42644.03120962207 43084.44552908032 43845.65692491803 33565.37245615568 39243.65387867477 27872.040334504156 27384.90727463135 46444.03066589623 31617.65438072292 2.174961502809741 1.3487411398747486 1.3626705197760853 1.3867460374179574 1.0616022318410905 1.2411943468710118 0.8815340948093088 0.8661270992742508 1.4689271413572302 1.0 14.948442721982587 -1.5228787454718746 0.6807495394126651 1.08965314193972 112.80455315731847 0.7199387788165668 0.19207175995264067 137.07429275645407 0.7854606860417082 0.07704209541070826 23226.447092933784 0.02999999998676909 1.5228787454718746 111.71490001537875 up GGS(ph)PDLWK ddPTM_PC-9_AZD4547_30min_R2 4 GGSPDLWK 8 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 GGS(1)PDLWK;GGS(1)PDLWK;GGS(1)PDLWK;GGS(1)PDLWK 109.29 0.0037804 257015800.0 175887.0 176020.0 219972.0 284397.0 249884.0 207081.0 199828.0 242060.0 207141.0 199326.0 True False 231815.4073231288 232915.02274129327 217055.0275528484 218833.66553984952 215191.91991181116 194132.1923340194 217612.30488186982 204655.18898543954 218090.0503732673 192347.65741011212 1.2051896573341982 1.2109064694491487 1.1284516301129506 1.137698625948251 1.1187654833403657 1.0092776535359742 1.1313488701236945 1.06398586674277 1.133832630507523 1.0 17.553356733687174 -1.5228787452803376 0.23540169027710353 1.0424817510110274 2.104395973792482 0.5999803565439636 0.04273654838778904 34.79376497471811 0.4606602318131915 0.05922438669139814 14.34333752909019 0.029999999999999995 1.5228787452803376 1.0619142227814546 GGS(ph)PDLWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GGSPDLWK 8 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 GGS(1)PDLWK;GGS(1)PDLWK;GGS(1)PDLWK 128.27 0.0036543 99710000.0 708370.0 700740.0 768810.0 844730.0 918420.0 797040.0 867650.0 767870.0 713240.0 620043.0 True False 828283.0500547596 770304.8361706745 787141.34612816 797402.5167516104 738462.1939331348 755241.81929127 785459.9107579817 747714.2261255181 723669.7856824873 732451.887642311 1.1308361191079996 1.0516797746951112 1.0746662810329957 1.088675625259659 1.008205735273849 1.0311145783545148 1.0723706553426986 1.020837325619209 0.9880099947750938 1.0 19.4823744711874 -1.5228787452803527 0.1871978828070774 0.9916381632951139 1.5140300458315454 0.6117226697019483 0.026674804480755526 41.01755930208803 0.4746876428296403 0.05781230140924752 6.162583809360636 0.029999999999998955 1.5228787452803527 0.5223918825364315 GGS(ph)PDLWK ddPTM_PC-9_Lapatinib_30min_R1 6 GGSPDLWK 8 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 GGS(1)PDLWK;GGS(1)PDLWK;GGS(1)PDLWK;GGS(1)PDLWK;GGS(1)PDLWK;GGS(1)PDLWK 125.57 0.0034478 253780400.0 697739.0 608137.0 630218.0 567207.0 637894.0 654587.0 566913.0 560070.0 600439.0 497836.0 True False 687789.1139103384 606728.8961403267 578403.908751832 608921.2949270852 600374.3290678569 626591.8399268255 596264.9812133873 586092.8968360579 532811.2369170238 583886.2892752279 1.177950444364919 1.0391216702372874 0.9906105338931641 1.0428765088540322 1.028238443161759 1.073140184032421 1.0212005182610555 1.0037791734475714 0.9125256864284258 1.0 19.155327908829967 -4.768839050469442 3.622636270858681 1.013739034924452 1.1988611478108842 0.6164270216101237 0.03966055085850871 0.2025531382717586 4.4684652529489375 0.010413205419000232 0.10427574991024707 1.7027894452261492e-05 4.768839050469442 0.1851221128864322 GGS(ph)PLPGPAQPVAQLDLQTFR ddPTM_PC-9_AZD4547_30min_R2 1 GGSPLPGPAQPVAQLDLQTFR 21 0 P22674-2;P22674 P22674-2 CCNO Cyclin-O 1 GGS(1)PLPGPAQPVAQLDLQTFR 129.75 1.3669e-06 0.0 5369.1 4799.5 5114.2 7232.8 7810.4 7984.0 5162.6 7435.4 2950.3 6355.1 True False 7076.362115782335 6350.844515662071 5046.38236644108 5565.389705646062 6726.060777317527 7484.759217865506 5622.0613987186 6286.429778494321 3106.246834843176 6132.6098833418955 1.1538907985984839 1.0355859310263595 0.8228767951062154 0.9075075394512567 1.0967697122863842 1.2204851376893344 0.9167485794245438 1.0250822892827813 0.5065130334281858 1.0 12.58228546370704 -8.20927771122372 24.98356305193392 0.753256127000685 1.0178938998858649 0.31785106173828326 0.15758691374713418 341.84772943662654 163733.05861772966 0.10526422975287576 0.039786045120532396 6.176213335767732e-09 8.20927771122372 0.26463777288517987 GGS(ph)PQMDDIK ddPTM_PC-9_AZD4547_30min_R2 3 GGSPQMDDIK 10 0 A0A3B3IUB1;Q13144;A0A3B3ITG6 A0A3B3IUB1 EIF2B5 Translation initiation factor eIF-2B subunit epsilon 1 GGS(1)PQMDDIK;GGS(1)PQMDDIK;GGS(1)PQMDDIK 84.18799999999999 0.011186 69373000.0 367876.0 444940.0 389044.0 262863.0 301810.0 411225.0 447350.0 450110.0 421247.0 316775.0 True False 484852.9157038509 588758.1537240719 383885.0223631662 202263.99654286576 259908.8911198148 385511.0357423276 487163.2833682188 380555.84199882654 443513.2564272054 305684.803668806 1.5861204413326497 1.9260301678652028 1.255819778267703 0.6616750133317343 0.8502512653570209 1.2611390265903086 1.5936784476078687 1.2449288856738183 1.4508842150613728 1.0 18.22168530858324 -10.541320508515653 16.002551820336976 1.0000010444267302 1.3025030679781924 0.06820754513163019 0.34618236722824247 0.0 0.0 0.37762704308002415 0.09158801092403591 2.8752756834676028e-11 10.541320508515653 0.30250202355146216 GGS(ph)PQMDDIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GGSPQMDDIK 10 0 A0A3B3IUB1;Q13144;A0A3B3ITG6 A0A3B3IUB1 EIF2B5 Translation initiation factor eIF-2B subunit epsilon 1 GGS(1)PQMDDIK;GGS(1)PQMDDIK;GGS(1)PQMDDIK 85.92399999999999 0.010209999999999999 66119000.0 334254.0 657310.0 381467.0 329263.0 356022.0 261391.0 381473.0 187546.0 234388.0 277732.0 True False 390836.60038257204 722563.3927895462 390562.62000165356 310815.46159504855 286262.04482531146 247683.19580744326 345337.1158146485 182623.11622141243 237815.48108146904 328082.6130746973 1.191274955779467 2.2023824609841 1.1904398600749102 0.9473695014867569 0.8725303731963869 0.7549415480638444 1.0525919449928993 0.5566375935314594 0.7248646273959163 1.0 18.323699613872023 -5.538030489738899 3.61777804210575 0.8350983062026759 1.7065033068683622 0.6140389442171874 0.267095749081686 0.12856987520907753 3.6117285176071987 0.0695896495997996 0.13963903845389222 2.897140186202327e-06 5.538030489738899 0.8714050006656863 GGS(ph)PQMDDIK ddPTM_PC-9_Lapatinib_30min_R1 5 GGSPQMDDIK 10 0 A0A3B3IUB1;Q13144;A0A3B3ITG6 A0A3B3IUB1 EIF2B5 Translation initiation factor eIF-2B subunit epsilon 1 GGS(1)PQMDDIK;GGS(1)PQMDDIK;GGS(1)PQMDDIK;GGS(1)PQMDDIK;GGS(1)PQMDDIK 136.38 0.00011522 112908000.0 250576.0 608495.0 453107.0 397820.0 601808.0 579403.0 584541.0 676646.0 497416.0 486280.0 True False 247002.7402899892 607086.0672133204 415854.2915036 427077.00988861587 566410.8366400514 554623.2843443614 614805.6727989209 708085.4433776686 441391.772057308 570332.8500726299 0.43308524181718494 1.0644416977489726 0.7291431511452346 0.748820640147642 0.9931232903170859 0.9724554429465743 1.0779769615596009 1.241530175383544 0.773919601511816 1.0 19.121444605990632 -6.318231107310579 4.131107312248889 1.027449918308415 0.7647183469402962 0.3439228051487935 0.17840211459133953 0.2661112847460877 9.40614388466188 0.054443486000054386 0.06362966076416171 4.805835406255004e-07 6.318231107310579 -0.26273157136811875 GGS(ph)PYNQFDIIPGDTLGGHTGPAGDSWLPAK ddPTM_PC-9_AZD4547_30min_R2 1 GGSPYNQFDIIPGDTLGGHTGPAGDSWLPAK 31 0 Q9UPQ9-1;Q9UPQ9;H0Y720;Q9UPQ9-2 Q9UPQ9-1 TNRC6B Trinucleotide repeat-containing gene 6B protein 1 GGS(0.53)PY(0.469)NQFDIIPGDT(0.001)LGGHTGPAGDSWLPAK 50.766999999999996 0.0051034999999999995 12130000.0 17452.0 14354.0 32751.0 46215.0 41924.0 37631.0 24270.0 46075.0 32558.0 33521.0 True False 23001.372975849452 18993.649792231146 32316.700340876767 35560.845764632344 36103.57626091623 35277.92762117949 26429.98298278009 38955.16744817032 34278.949411525646 32347.4399929983 0.7110724366697385 0.5871762895716749 0.999049703712931 1.0993403426153536 1.1161185017649295 1.0905941128205356 0.8170656777940059 1.2042735825957875 1.0597113533233364 1.0 14.981363920034678 -5.3280743192267 4.976831250059476 1.056440074834149 0.6490791350312103 0.7229134467040281 0.09907616495541942 0.09753534695109663 4.729207327480688 0.02611351793442632 0.05755149774581097 4.69813704224417e-06 5.3280743192267 -0.40736093980293864 GGS(ph)PYNQFDIIPGDTLGGHTGPAGDSWLPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGSPYNQFDIIPGDTLGGHTGPAGDSWLPAK 31 0 Q9UPQ9-1;Q9UPQ9;H0Y720;Q9UPQ9-2 Q9UPQ9-1 TNRC6B Trinucleotide repeat-containing gene 6B protein 1 GGS(0.945)PY(0.052)NQFDIIPGDT(0.003)LGGHT(0.001)GPAGDSWLPAK;GGS(0.494)PY(0.051)NQFDIIPGDT(0.448)LGGHT(0.005)GPAGDS(0.001)WLPAK 60.595 0.00044544 9062700.0 17168.2 18939.3 29277.0 28435.0 29228.0 25824.0 20151.1 17057.2 20944.8 16840.5 True False 20074.437172593567 20819.468538526788 29975.074713640788 26841.879137513824 23500.983214953554 24469.74397944618 18242.241926669925 16609.466573597292 21251.07807633133 19893.54934067536 1.0090927882611855 1.0465436902181275 1.5067735877756228 1.3492755203130875 1.1813368651566993 1.2300340959978469 0.9169928208522806 0.8349172030169968 1.0682396445404692 1.0 14.2800130795201 -7.258377951317967 23.593850583512605 0.9412805013075609 1.2296863532555746 0.4477148384737506 0.14390590978517587 117.14459905739282 902818.6955732408 0.06118443741555111 0.04527948915107924 5.515971945694782e-08 7.258377951317967 0.2884058519480137 GGS(ph)REYDTGGGSSSSR ddPTM_PC-9_AZD4547_30min_R2 2 GGSREYDTGGGSSSSR 16 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 GGS(1)REYDTGGGSSSSR;GGS(0.986)REY(0.004)DT(0.01)GGGSSSSR 180.02 2.2527e-05 67253000.0 20107.1 19802.6 34920.0 60449.0 53329.0 36528.0 25993.0 38226.0 30540.0 37678.0 True False 26500.739546338693 26203.403189050885 34456.93798367733 46513.416977740104 45925.18887554628 34243.898385545 28306.32664488679 32319.050046093518 32154.28205135428 36358.90468829064 0.7288651782426558 0.7206873643113257 0.947689108873903 1.279285428879262 1.2631070509210487 0.9418297575001818 0.7785252852790921 0.8888895395273512 0.8843578300011206 1.0 15.150021118559664 -5.3140597140818775 4.619245891887214 1.0061639704833203 0.7225653633056337 0.3484654081543641 0.1504736991463898 0.2479815173221854 11.489357979571253 0.04644414889796826 0.10558747962880079 4.852217791552862e-06 5.3140597140818775 -0.2835986071776866 GGS(ph)REYDTGGGSSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGSREYDTGGGSSSSR 16 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 GGS(1)REYDTGGGSSSSR;GGS(0.967)REYDT(0.003)GGGS(0.01)S(0.003)S(0.015)S(0.001)R 125.96 0.00014419 28390400.0 6526.700000000001 6110.4 9130.0 11758.9 11697.7 13471.400000000001 13178.400000000001 12982.0 12647.2 8392.3 True False 7631.541401799051 6717.000129773231 9347.69382571781 11100.086955868168 9405.619657642066 12764.936068955669 11930.046548646329 12641.236255565987 12832.141373848302 9913.757556589755 0.7697930233049025 0.6775433120520873 0.9429011928483486 1.1196649597800432 0.9487441672799507 1.2875981681104065 1.203382923230388 1.275120576976714 1.2943771623019642 1.0 13.275216262435174 -5.6399359777869345 0.8437109441527656 1.2207111609844972 0.6478545051521194 0.7102456767414682 0.112482702933107 0.45864069597744966 0.5457134977491306 0.04746263253405548 0.19538626001548423 2.2912053895665246e-06 5.6399359777869345 -0.5728566558323778 GGS(ph)REYDTGGGSSSSR ddPTM_PC-9_Lapatinib_30min_R1 2 GGSREYDTGGGSSSSR 16 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 GGS(0.994)REYDT(0.001)GGGSS(0.001)S(0.004)SR;GGS(1)REYDTGGGSSSSR 95.9 0.011579 28026500.0 14299.599999999999 8641.6 11348.4 12780.8 10824.599999999999 11311.599999999999 11089.2 9503.1 13502.9 9371.1 True False 14095.685081774522 8621.590906138326 10415.378358090824 13720.74266749895 10187.918309982417 10827.829236627485 11663.344516127676 9944.648718772187 11982.061210159354 10990.88214879415 1.2824889659399188 0.7844312030116921 0.947638071001747 1.2483750150122666 0.9269427305341611 0.9851647110796695 1.0611836573470406 0.9048089665726469 1.090181938805881 1.0 13.424019563890804 GGS(ph)SKDLLDNQSQEEQR ddPTM_PC-9_AZD4547_30min_R2 3 GGSSKDLLDNQSQEEQR 17 1 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3;O43432-4 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 GGS(0.987)S(0.013)KDLLDNQSQEEQR;GGS(0.84)S(0.16)KDLLDNQSQEEQR;GGS(0.823)S(0.176)KDLLDNQSQEEQR 84.10700000000001 0.0016331 15935400.0 29309.4 37273.0 43197.0 35796.0 40003.0 43841.0 33553.4 35178.0 30490.0 35293.0 True False 38629.17952660798 49320.768336758454 42624.179555581584 27543.785242686987 34449.273952042524 41099.61533948419 36539.587598451275 29742.048410021394 32101.639153431333 34057.40281235313 1.1342373856117 1.4481658689155554 1.2515393434557833 0.808745910380942 1.0115061956382432 1.2067747962442028 1.0728823862399108 0.8732917355410762 0.9425744919629511 1.0 15.055680800103065 -5.618055770817202 7.46521376159062 0.9969619562625938 1.3053731344266528 0.5348248549910828 0.12391093256648633 0.1723980103600061 11.632340328349525 0.035028151605718795 0.06092550415449717 2.40959597560504e-06 5.618055770817202 0.30841117816405905 GGS(ph)SKDLLDNQSQEEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGSSKDLLDNQSQEEQR 17 1 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3;O43432-4 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 GGS(0.81)S(0.19)KDLLDNQSQEEQR 53.008 0.030258999999999998 7854600.0 5923.7 8149.5 6054.9 7051.7 7362.5 4032.9 7246.0 5015.5 6271.8 6050.9 True False 6926.465411591924 8958.528501830804 6199.27177933612 6656.61611091986 5919.8709771484755 3821.407624485301 6559.606423502956 4883.848439361518 6363.513209920116 7147.880271101956 0.9690237033760642 1.2533126132580994 0.8672881391703007 0.9312713501696133 0.8281995154677984 0.5346211015781567 0.9176995381445711 0.6832582883496728 0.8902657807024351 1.0 12.803299753717749 -5.618142976484566 1.6948575731978632 0.7925656536366863 1.1076326443217221 0.3419170262779002 0.14649712467376147 0.3702195787998127 2.1062460235582843 0.04316000864018347 0.11018556675727091 2.409112180994786e-06 5.618142976484566 0.31506699068503585 GGS(ph)SKDLLDNQSQEEQR ddPTM_PC-9_Lapatinib_30min_R1 3 GGSSKDLLDNQSQEEQR 17 1 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3;O43432-4 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 GGS(0.957)S(0.043)KDLLDNQSQEEQR;GGS(0.606)S(0.394)KDLLDNQSQEEQR;GGS(0.827)S(0.173)KDLLDNQSQEEQR 71.354 0.0063617 22450100.0 27898.300000000003 35084.0 39460.8 30234.1 38711.0 44030.0 37650.0 44211.0 35621.4 34293.0 True False 27500.46512607836 35002.765153554516 36216.485347093 32457.616572000963 36434.095088754264 42146.939538943065 39599.332777135176 46265.204460190565 31609.342822028644 40220.49935744978 0.683742508557011 0.8702717696882891 0.9004484261925222 0.806991884500038 0.905858844887907 1.0478969732417422 0.9845559704569021 1.1502891609828103 0.785901302246608 1.0 15.295643373078448 -6.532255730183205 3.876793842712236 1.0020952287996077 0.8268011179678795 0.4111686819249082 0.09980731391839355 0.22086169716937107 7.455141670342839 0.0322986279882734 0.03397401087318918 2.9359203540393963e-07 6.532255730183205 -0.1752941108317282 GGSDGYGS(ph)GR ddPTM_PC-9_AZD4547_30min_R2 2 GGSDGYGSGR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 GGSDGYGS(1)GR;GGSDGYGS(1)GR 102.05 0.0033668 22665700.0 126564.0 126189.0 152612.0 188578.0 138965.0 111458.0 98481.0 122603.0 122555.0 144126.0 True False 166808.71930526107 166977.1264896096 150588.2651650908 145104.2556010565 119672.10846050529 104488.51364038752 107245.61821702393 103657.52348666365 129033.0070990087 139080.1926085402 1.1993707815372856 1.2005816454366658 1.0827441517063583 1.0433135939743183 0.8604540029459007 0.7512824916376439 0.7711063394834451 0.7453075922782304 0.9277597670732981 1.0 17.0855574445672 -6.005207586770386 1.5451186664161238 0.815952085531276 1.188329789727808 0.7677932405108394 0.07991600391690855 0.1691957064640232 0.8160623069707502 0.02712607943530145 0.04658261315046043 9.8808069282654e-07 6.005207586770386 0.37237770419653204 GGSDGYGS(ph)GR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGSDGYGSGR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 GGSDGYGS(1)GR;GGSDGYGS(1)GR 100.09 0.0041234999999999996 19543400.0 74088.0 113773.0 86921.0 86720.0 150403.0 159351.0 83531.0 90571.0 130450.0 118483.0 True False 86629.63509529899 125067.63154043733 88993.52628972798 81861.3595500333 120932.61182696934 150994.35303859683 75618.33896793064 88193.60721790668 132357.58446284648 139963.02998908787 0.6189465539725242 0.8935761933003891 0.6358359510841277 0.5848784465184526 0.8640325365662473 1.0788159776933166 0.5402736635083292 0.6301207342023293 0.9456610397271741 1.0 17.09468627664303 -6.282497071468375 24.49959448569474 0.8212961131858648 0.6949373778316486 0.1655489416353667 0.1708520377308338 1532.1548418256812 1782582.41676686 0.055412709180630244 0.06290349886928377 5.217986228160971e-07 6.282497071468375 -0.12635873535421627 GGSDGYGS(ph)GR ddPTM_PC-9_Lapatinib_30min_R1 2 GGSDGYGSGR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 GGS(0.003)DGYGS(0.996)GR;GGSDGYGS(1)GR 110.93 0.0016683 20264400.0 50113.0 75811.0 66333.0 43876.0 70684.0 53105.0 76821.0 95367.0 62137.0 62575.0 True False 49398.37943040131 75635.46428731378 60879.3567927847 47102.787406045296 66526.50609009078 50833.82294380129 80798.41549196007 99798.09897435002 55138.47672838221 73391.00537405354 0.6730849261245505 1.0305822069315014 0.8295206814854158 0.6418059974240098 0.9064667495835994 0.69264377405263 1.100930762293731 1.359813760088268 0.7512974709551495 1.0 16.16331564020105 -7.274392229457802 24.062979456780425 1.0829950206025194 0.8059403939178525 0.33117257622794694 0.17675239493405437 524.0576951185938 973555.7886855921 0.0711996768861979 0.04838336114283224 5.316279070532782e-08 7.274392229457802 -0.27705462668466685 GGSDGYGSGR ddPTM_PC-9_AZD4547_30min_R2 4 GGSDGYGSGR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;;; 140.11 0.00056398 33910800.0 73451.0 55946.8 58607.0 66122.0 56804.0 55497.3 47986.8 56765.0 85798.0 94475.0 False True 96806.89012429076 74030.50900069659 57829.83288686647 50878.59447471635 48917.74510841246 52027.045057821546 52257.532237250576 47993.2735799325 90333.1071199115 91167.45900595219 1.061857939003986 0.812027776225103 0.6343253779080411 0.5580784528764212 0.5365702372511961 0.5706756075588855 0.5732037813386766 0.5264298698595855 0.9908481392907286 1.0 16.476231345296455 -10.41531730385251 12.591351782044221 0.9999998746769101 0.6765651063333846 0.18761067279125265 0.18585830904402623 0.0 0.0 0.1865908891221953 0.045254937919336755 3.8431089455909175e-11 10.41531730385251 -0.32343476834352547 GGSDGYGSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GGSDGYGSGR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;;; 145.9 0.00056398 35046500.0 41034.1 67934.6 66684.4 45548.1 118039.0 117644.0 56363.7 86610.4 116761.0 112656.0 False True 47980.362669582224 74678.69812386973 68274.4089979952 42996.18762593261 94910.10530005141 111474.54153957429 51024.522298149794 84336.96877130447 118468.40873489018 133079.64101559474 0.36053871428733203 0.5611579468802341 0.5130342137757538 0.32308614073353387 0.7131827571501302 0.8376528572579431 0.3834134350585644 0.6337330648601732 0.890206855314613 1.0 17.021930354083125 -10.33942664393139 0.08865776601506209 1.7809190950260485 0.018806918495218608 0.5404198622616581 0.15158612567751714 53.55570937126128 1.0085136184508154 15.130157623378558 5.8568355981764695 4.576920364742625e-11 10.33942664393139 -1.7621121765308299 GGSDGYGSGR ddPTM_PC-9_Lapatinib_30min_R1 4 GGSDGYGSGR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;;; 152.06 0.00050978 51472000.0 52862.4 77218.0 56414.4 56000.0 87661.0 48678.9 92271.0 117298.0 97644.0 72191.0 False True 52108.57248222311 77039.2064652596 51776.22579788151 60118.42681052368 82504.95232815709 46597.01692305828 97048.34089452963 122748.0932974021 86646.30448309629 84669.11816153907 0.615437760705218 0.9098855419549492 0.6115125198197807 0.7100396002214708 0.9744397263090304 0.5503425326121439 1.1462070587456976 1.449738652801517 1.0233519182021593 1.0 16.369548242858293 -7.350683818134226 6.60907662060202 1.1980791337064713 0.7425351540133877 0.5985998088366111 0.16955590569915424 0.15963833588009582 9.960498155637833 0.0680402244804633 0.04558859303035901 4.4598082016991553e-08 7.350683818134226 -0.4555439796930837 GGSFWSSIPASPAS(ph)RPGSFTFPGDSDSLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGSFWSSIPASPASRPGSFTFPGDSDSLQR 30 1 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 GGSFWS(0.001)S(0.003)IPAS(0.154)PAS(0.572)RPGS(0.091)FT(0.091)FPGDS(0.065)DS(0.023)LQR 51.052 0.0046248999999999995 18741000.0 11758.0 10136.0 8331.8 18318.0 27995.0 29916.0 38751.0 37358.0 35725.0 22378.0 True False 13748.397168914333 11142.235093509667 8530.461710527456 17291.70184775727 22509.580713789015 28347.15229589187 35080.22474705535 36377.392084072904 36247.4105399401 26434.954255849458 0.5200840158772783 0.42149628804612527 0.32269629173426156 0.6541226317397923 0.8515082150674861 1.0723359693205932 1.3270393588554399 1.3761095151516447 1.371192482087211 1.0 14.690159209770622 -6.528325578354004 1.2893807052163806 1.3016894509319614 0.42117971760543743 0.8977619211081267 0.1213125705760309 0.12014389020527787 0.415314827494307 0.052444940446158855 0.0585496070085776 2.9626095717697203e-07 6.528325578354004 -0.8805097333265239 GGSGS(ph)GPTIEEVD ddPTM_PC-9_AZD4547_30min_R2 1 GGSGSGPTIEEVD 13 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 1 GGS(0.485)GS(0.502)GPT(0.013)IEEVD 88.338 0.028288 0.0 21364.0 25283.0 26506.0 36615.0 32476.0 33161.0 24740.0 37000.0 30098.0 27492.0 True False 28157.307601194585 33455.23531398771 26154.51312128725 28173.97744611085 27967.267976565094 31087.437427810364 26941.81207226943 31282.500175416208 31688.918833715165 26529.513447913538 1.0613578592942143 1.2610572515651943 0.9858647868773568 1.061986210241886 1.0541945306111382 1.171805788630296 1.0155411302648039 1.179158458251954 1.1944779498474896 1.0 14.695310596287596 -7.7950263551849766 24.9991495522328 1.140113587223072 1.0911664370665228 0.025422674144431334 0.08910219432206666 626.360185048352 466198.3437392252 0.04720980802500727 0.02268083707666528 1.6031481006057024e-08 7.7950263551849766 -0.04894715015654927 GGSGS(ph)GPTIEEVD ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGSGSGPTIEEVD 13 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 1 GGS(0.335)GS(0.665)GPTIEEVD;GGS(0.124)GS(0.868)GPT(0.008)IEEVD 96.64 0.0032124000000000002 14295300.0 49580.0 44625.0 51809.0 59706.0 67435.0 55622.0 58714.0 60952.0 55434.0 47275.0 True False 57972.9147503634 49055.075083649295 53044.32304672663 56360.86638946374 54221.59583619798 52705.084403065186 53152.18486745133 59352.07458398233 56244.61737917532 55845.583271305935 1.0380931016285133 0.8784056358643911 0.9498391804599771 1.0092269269649219 0.9709200380768093 0.9437645972290458 0.9517706102061879 1.0627890534447701 1.0071453118491183 1.0 15.769155564563285 -7.7458105240215405 24.997574783999156 1.0262253909520234 0.9607006308453808 0.29398237563133645 0.042537714153394655 263.2260524948832 421018.2453234006 0.01977834121383498 0.011366386750255432 1.7955168122429042e-08 7.7458105240215405 -0.06552476010664254 GGSGSHNWGTVKDELTES(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 GGSGSHNWGTVKDELTESPK 20 1 Q8NC51;Q8NC51-2 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 GGSGSHNWGT(0.006)VKDELT(0.1)ES(0.894)PK 57.04600000000001 0.0092946 9813400.0 10079.0 11012.0 18405.0 28303.0 31321.0 25816.0 18163.0 25114.0 14735.0 27722.0 True False 13283.912343776465 14571.413648603118 18160.937674386627 21778.180626990983 26972.61978981388 24201.721438929857 19779.47181360669 21233.208362308193 15513.862017901292 26751.4612179201 0.4965677289761623 0.5446959898714658 0.6788764743146476 0.8140931237207466 1.008267158570973 0.9046878315087238 0.7393791184893087 0.7937214415818388 0.5799257801853815 1.0 14.707330076082743 -5.475730506205528 2.235987917996405 0.8321915951202837 0.5111578486776097 0.5349011367816177 0.11797717736813591 0.2620630252262886 2.546563056215064 0.035560761534399916 0.09204083337363482 3.3440248323025737e-06 5.475730506205528 -0.321033746442674 GGSGSHNWGTVKDELTES(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 GGSGSHNWGTVKDELTESPK 20 1 Q8NC51;Q8NC51-2 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 GGSGSHNWGT(0.042)VKDELT(0.154)ES(0.804)PK 52.172 0.016038999999999998 6968400.0 41664.0 37567.0 54015.0 38458.0 52671.0 72687.0 56378.0 56909.0 73390.0 47564.0 True False 41069.863719758134 37480.0159196096 49574.09520392969 41286.32961212713 49572.99533517023 69578.34645167286 59296.97698032736 59553.19989651861 65124.04536903885 55785.374024953846 0.73621203474206 0.6718609774462404 0.8886575750438505 0.7400923689004751 0.8886378589663179 1.2472506937131793 1.062948452291504 1.0675414647193966 1.1674035803705043 1.0 15.767599301109941 -6.568802829144277 5.093652916023278 1.109422249003025 0.7670617605215544 0.8101236619170207 0.08026110245885593 0.08100609295194072 4.781351100994336 0.02648701954126267 0.026835225056974214 2.698964491427728e-07 6.568802829144277 -0.3423604884814706 GGSISVQVNSIKFDS(ph)E ddPTM_PC-9_AZD4547_30min_R2 11 GGSISVQVNSIKFDSE 16 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 GGSISVQVNS(0.005)IKFDS(0.995)E;GGSISVQVNSIKFDS(1)E;GGSISVQVNS(0.001)IKFDS(0.998)E;GGSISVQVNS(0.001)IKFDS(0.999)E;GGSISVQVNS(0.043)IKFDS(0.956)E;GGSISVQVNS(0.002)IKFDS(0.998)E;GGSISVQVNSIKFDS(1)E;GGSISVQVNS(0.023)IKFDS(0.977)E;GGSISVQVNS(0.123)IKFDS(0.877)E;GGSISVQVNS(0.006)IKFDS(0.994)E;GGSISVQVNS(0.024)IKFDS(0.976)E 181.69 9.657600000000001e-15 49913500.0 591853.0 486018.9 574466.0 820297.0 725155.0 671932.0 601325.0 635487.0 550197.3 678687.0 True False 780049.9426928402 643115.0048073987 566848.205490584 631190.2001123147 624479.7453364353 629915.9858189889 654841.7600791187 537287.0861885052 579279.6060279504 654926.3747062439 1.1910498230319682 0.9819653470145511 0.8655143957896553 0.9637574916652644 0.9535113708262781 0.9618119076385143 0.9998708028407572 0.8203778423635728 0.8844957668528413 1.0 19.320973205794687 -4.786200649724977 3.5380271850961464 0.9298125566676395 1.2205134178386887 0.6610695422785945 0.05559366082781894 0.17053674966116536 3.56443370969103 0.014465430757723314 0.13225511301319898 1.6360604654761576e-05 4.786200649724977 0.2907008611710492 GGSISVQVNSIKFDS(ph)E ddPTM_PC-9_LapatinibAZD4547_30min_R1 10 GGSISVQVNSIKFDSE 16 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 GGSISVQVNS(0.001)IKFDS(0.999)E;GGSISVQVNS(0.003)IKFDS(0.997)E;GGSISVQVNS(0.001)IKFDS(0.999)E;GGSISVQVNSIKFDS(1)E;GGSISVQVNS(0.007)IKFDS(0.993)E;GGSISVQVNS(0.001)IKFDS(0.999)E;GGSISVQVNSIKFDS(1)E;GGSISVQVNSIKFDS(1)E;GGSISVQVNSIKFDS(1)E;GGSISVQVNS(0.001)IKFDS(0.999)E 209.89 3.7124999999999995e-63 47682800.0 305691.1 248780.5 230842.80000000002 379882.6 373235.5 329396.3 369860.6 376235.7 332643.0 274448.2 True False 357438.5655555624 273477.7839069533 236346.96782819382 358599.00951800594 300102.6830684545 312122.17815895466 334824.7264091433 366359.91152967606 337507.2745762715 324203.4861292436 1.1025130229878823 0.8435374559727327 0.7290081012083077 1.1060923921559886 0.9256614931920215 0.9627354162210559 1.0327610304463708 1.130030759088219 1.0410353034936963 1.0 18.306540078538198 -7.2528020928197 2.6469342434414695 1.0665481204612943 0.9337293873591788 0.18579926595267793 0.10852690826870141 0.45039506798569634 6.263558091677284 0.05093499611007805 0.03439624252849494 5.587247465513971e-08 7.2528020928197 -0.13281873310211556 GGSISVQVNSIKFDS(ph)E ddPTM_PC-9_Lapatinib_30min_R1 19 GGSISVQVNSIKFDSE 16 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 GGSISVQVNS(0.003)IKFDS(0.997)E;GGSISVQVNSIKFDS(1)E;GGSISVQVNS(0.01)IKFDS(0.99)E;GGSISVQVNS(0.003)IKFDS(0.997)E;GGSISVQVNS(0.095)IKFDS(0.905)E;GGSISVQVNS(0.022)IKFDS(0.978)E;GGSISVQVNS(0.001)IKFDS(0.999)E;GGSISVQVNS(0.002)IKFDS(0.998)E;GGSISVQVNS(0.008)IKFDS(0.992)E;GGSISVQVNS(0.001)IKFDS(0.999)E;GGSISVQVNS(0.086)IKFDS(0.914)E;GGSISVQVNS(0.004)IKFDS(0.996)E;GGSISVQVNS(0.009)IKFDS(0.991)E;GGSISVQVNS(0.025)IKFDS(0.975)E;GGSIS(0.001)VQVNS(0.019)IKFDS(0.98)E;GGSISVQVNS(0.009)IKFDS(0.991)E;GGSISVQVNSIKFDS(1)E;GGSISVQVNS(0.007)IKFDS(0.993)E;GGSISVQVNS(0.05)IKFDS(0.95)E 167.69 7.3128e-21 42647600.0 892731.0 639645.0 612243.0 661583.8 635075.0 639761.0 544043.9 560907.7 605656.0 529233.9 True False 880000.4922331847 638163.9413021707 561906.743866324 710238.879630859 597721.13710549 612399.9133857312 572211.8311147523 586969.519436232 537440.643439578 620711.2744551547 1.4177291898002464 1.028117206123468 0.905262667187014 1.1442338956293157 0.9629616243561149 0.9866099402226599 0.9218647294863881 0.9456401769912424 0.8658464338533731 1.0 19.2435628253709 -4.766366448021617 3.9056337177890863 0.9695383487485827 1.4675624479778062 0.7848321357847157 0.07042416493277251 0.11404452271276755 3.1736318031170225 0.017958693451151145 0.16636479596329962 1.7125117184283076e-05 4.766366448021617 0.4980240992292235 GGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKS(ph)PPTNK ddPTM_PC-9_AZD4547_30min_R2 2 GGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNK 37 1 Q9UPQ9-1;Q9UPQ9;H0Y720;Q9UPQ9-2 Q9UPQ9-1 TNRC6B Trinucleotide repeat-containing gene 6B protein 1 GGSPYNQFDIIPGDT(0.018)LGGHT(0.063)GPAGDS(0.014)WLPAKS(0.662)PPT(0.243)NK;GGSPYNQFDIIPGDT(0.038)LGGHT(0.038)GPAGDS(0.162)WLPAKS(0.623)PPT(0.139)NK 60.876000000000005 4.7521e-05 16173000.0 21643.4 17439.3 44183.0 79254.0 63810.0 58346.0 38248.3 61764.0 43974.0 59779.0 True False 28525.55098931356 23076.21268090124 43597.10455134062 60983.21476209393 54951.08294077529 54697.61539649058 41652.32460322486 52219.792995524556 46298.37586529973 57686.15540531151 0.49449561664993613 0.40003034556150147 0.7557637399306797 1.0571551238527994 0.9525870211783192 0.9481931151794915 0.7220506256755963 0.9052396130166852 0.8025907696569559 1.0 15.815937495218863 -5.40880416733042 3.879619066160027 0.9043335784895169 0.44990344681224526 0.7932870259478444 0.09358109219743276 0.10004158779374761 2.6118446411655665 0.02608770596052716 0.05824592451570578 3.9011785950694715e-06 5.40880416733042 -0.45443013167727164 GGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKS(ph)PPTNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNK 37 1 Q9UPQ9-1;Q9UPQ9;H0Y720;Q9UPQ9-2 Q9UPQ9-1 TNRC6B Trinucleotide repeat-containing gene 6B protein 1 GGSPYNQFDIIPGDT(0.005)LGGHT(0.017)GPAGDS(0.185)WLPAKS(0.719)PPT(0.074)NK 66.1 2.2217e-06 5324900.0 10664.0 9110.6 13536.0 18980.0 23814.0 18884.0 21633.0 23523.0 19139.0 15499.0 True False 12469.204576399256 10015.040158142183 13858.749575565866 17916.612133990242 19147.817650229383 17893.68979661793 19583.765630643025 22905.546174678693 19418.871667569314 18308.84600998351 0.681048088426764 0.547005537797475 0.7569428225027901 0.9785768105876586 1.0458232943675638 0.9773248290395145 1.0696340785194394 1.2510644396806154 1.060627832960118 1.0 14.160253241785732 -5.729206560944552 1.8240269351096932 1.0781057204609856 0.6052933670369547 0.8544144262111038 0.0763786333885972 0.1248212057975354 0.8438122591805027 0.024969497287500513 0.05322606916343652 1.865492206648617e-06 5.729206560944552 -0.47281235342403094 GGSREYDTGGGSSS(ph)SR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGSREYDTGGGSSSSR 16 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 GGS(0.082)REYDT(0.001)GGGS(0.025)S(0.127)S(0.682)S(0.084)R 81.65100000000001 0.033955 3548700.0 3299.2 1086.1 3362.1 4191.2 2627.2 4793.2 3507.5 4304.6 4524.0 3329.1 True False 3857.689397829747 1193.9208302151585 3442.2652148352536 3956.3806520537337 2112.4190195130004 4541.836154053643 3175.244207899065 4191.608811100706 4590.154941432858 3932.6394768589016 0.9809415331687056 0.30359274915502127 0.8753065810102374 1.0060369569431762 0.5371504385141967 1.1549078375425663 0.8074079067210128 1.0658512776891131 1.1671944424204201 1.0 11.941282218517744 -6.761470739379345 0.6288380135149151 1.084899408928297 0.6805402643701526 0.24168239837417915 0.22827711327922828 1.094319284347655 0.9468351812994327 0.17656715527807873 0.1931492888986484 1.7319257154337117e-07 6.761470739379345 -0.4043591445581445 GGSSVEAPCPSDVT(ph)PEDDR ddPTM_PC-9_AZD4547_30min_R2 2 GGSSVEAPCPSDVTPEDDR 19 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 GGSSVEAPCPS(0.001)DVT(0.999)PEDDR;GGSSVEAPCPSDVT(1)PEDDR 249.49 5.777599999999999e-137 11570000.0 35115.3 44230.1 44237.1 42021.6 48450.3 58843.0 57825.8 71400.0 58788.0 49221.0 True False 46281.234956385924 58526.61485825293 43650.48714999231 32334.16934724816 41723.812158054345 55163.53790792339 62972.18417658197 60366.770608776234 61895.41366191933 47497.78777170638 0.9743871689105248 1.2321966475482091 0.9190004250259873 0.6807510594526903 0.8784369570767357 1.1613917299277539 1.3257919396004674 1.2709385729483529 1.3031220308493898 1.0 15.535572700464368 -6.893872818880823 4.66630656054631 1.2470256752362558 0.9392095293358849 0.4523368890480485 0.1516011224944982 0.20465836228033055 7.533629993095539 0.05913807950690715 0.05196075169720133 1.2768126627179678e-07 6.893872818880823 -0.307816145900371 GGSSVEAPCPSDVT(ph)PEDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGSSVEAPCPSDVTPEDDR 19 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 GGSSVEAPCPS(0.001)DVT(0.999)PEDDR 232.37 4.8195e-36 5501300.0 14725.0 17274.0 17322.0 12794.0 16064.0 11629.0 18483.0 11461.0 16850.0 10546.0 True False 17217.651667993163 18988.8485601111 17735.022174050824 12077.193658707649 12916.374516388876 11019.1547683155 16732.156434668097 11160.160893933273 17096.399372931864 12457.906317909934 1.3820662339738778 1.524240757278135 1.4235957247932036 0.9694400768887659 1.0368013843401465 0.8845109673423991 1.3430953811727857 0.8958295727339853 1.3723332746814338 1.0 13.60477400821863 -5.727054544405205 9.266196398230754 1.0694887406122486 1.4525491691430317 0.5291568665577376 0.16055289045830493 0.23246304667585185 58.47211684289482 0.04122275863645644 0.07084354229639175 1.8747590364174164e-06 5.727054544405205 0.38306042853078304 GGSSVEAPCPSDVT(ph)PEDDR ddPTM_PC-9_Lapatinib_30min_R1 2 GGSSVEAPCPSDVTPEDDR 19 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 GGSSVEAPCPS(0.001)DVT(0.999)PEDDR;GGSSVEAPCPS(0.032)DVT(0.968)PEDDR 300.5 2.0153999999999993e-121 21464500.0 21327.0 38784.0 37175.0 28893.0 54163.0 47237.0 52135.0 57968.0 45962.0 44323.0 True False 21022.873069107198 38694.198030881875 34118.61499964981 31017.887604222506 50977.23882855509 45216.78362482522 54834.29520148585 60661.404902588205 40785.27555868327 51984.171493314876 0.4044091204148694 0.7443457675546088 0.6563269937665053 0.5966794644060334 0.9806300141786568 0.8698182990305051 1.054826760267546 1.1669206829696077 0.78457104128183 1.0 15.665784787719812 -6.2634418550702655 24.147114711880032 0.9830933271998302 0.6147111833052642 0.6859746081600523 0.1243227743049117 65.45936519705273 789350.4759557375 0.03746587258700488 0.044654521258893756 5.452028845541179e-07 6.2634418550702655 -0.368382143894566 GGT(ph)PAFLPSSLSPQSSLPASR ddPTM_PC-9_AZD4547_30min_R2 1 GGTPAFLPSSLSPQSSLPASR 21 0 Q96JY6;Q96JY6-3;Q96JY6-5;A0A087WVI1;E5RGS7;H0YBP7;B3KPU0 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 GGT(0.95)PAFLPS(0.02)S(0.019)LS(0.005)PQS(0.005)S(0.001)LPASR 73.415 0.004392 3798900.0 11375.0 14763.0 18852.0 19049.0 14619.0 14778.0 13560.0 19622.0 10309.0 15590.0 True False 14992.013385301838 19534.85104380022 18602.01016232201 14657.547354116217 12589.40419230833 13853.929323849761 14766.813730799244 16589.870768703164 10853.912693759374 15044.198845226687 0.9965311904966341 1.298497264279271 1.2364905804355388 0.9742989643324776 0.836827824587201 0.9208818273659962 0.9815619882932182 1.1027420562157018 0.7214683085103709 1.0 13.876919659846912 -5.833684205823291 5.569025993140735 0.9330034482691536 1.1887924432319117 0.46825653383813703 0.1190600288776848 0.16623149075692298 9.150767325267516 0.03308070719630123 0.050280879863391685 1.4666138912950243e-06 5.833684205823291 0.2557889949627581 GGT(ph)PAFLPSSLSPQSSLPASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGTPAFLPSSLSPQSSLPASR 21 0 Q96JY6;Q96JY6-3;Q96JY6-5;A0A087WVI1;E5RGS7;H0YBP7;B3KPU0 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 GGT(0.991)PAFLPS(0.005)S(0.003)LS(0.001)PQSSLPASR 81.639 0.0052832999999999995 0.0 12116.0 11137.0 11881.0 13509.0 17434.0 15232.0 17088.0 12926.0 13673.0 13013.0 True False 14166.999498092031 12242.60775813114 12164.288098943407 12752.134526768927 14017.932851016165 14433.207105596492 15469.300933593504 12586.70619622908 13872.941758225359 15372.153889148676 0.9216014619846232 0.7964145978770933 0.7913196931713176 0.8295606860773596 0.9119042752305214 0.9389189836165384 1.0063196768094682 0.8187991277601075 0.9024722142560893 1.0 13.908031703815883 -6.299733291230094 4.343980935685922 0.9261455766448796 0.8283597318254688 0.3798024167739463 0.05937649102105393 0.23943773979402744 10.43606739178596 0.01906805485662884 0.022487155882408957 5.014951170785959e-07 6.299733291230094 -0.09778584481941077 GGT(ph)RATAGPR ddPTM_PC-9_AZD4547_30min_R2 1 GGTRATAGPR 10 1 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 GGT(0.998)RAT(0.002)AGPR 71.888 0.023063 1854100.0 3411.9 1195.9 5296.4 5808.2 2915.1 2452.7 3163.3 2205.0 4323.2 7133.1 True False 4496.813228071327 1582.4512879008796 5226.166275393714 4469.2092257954655 2510.388683288734 2299.3322812698802 3444.827571875906 1864.2679158592643 4551.715526012274 6883.372340146664 0.6532863552715373 0.22989476810245635 0.7592450353023269 0.6492761113225265 0.3647033109987546 0.33404153772987505 0.5004563753996354 0.27083641908866174 0.6612624308385575 1.0 12.748899835985368 -8.535289824250286 20.08531232696721 1.0000000088983068 0.47046664110540126 0.48893386903293856 0.16649713574522443 101.5138791960754 164285.4507015781 0.16020772815705991 0.041365456794762584 2.9154807331680956e-09 8.535289824250286 -0.5295333677929055 GGTPAFLPS(ph)SLSPQSSLPASR ddPTM_PC-9_AZD4547_30min_R2 1 GGTPAFLPSSLSPQSSLPASR 21 0 Q96JY6;Q96JY6-3;Q96JY6-5;A0A087WVI1;E5RGS7;H0YBP7;B3KPU0 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 GGT(0.035)PAFLPS(0.926)S(0.018)LS(0.018)PQS(0.003)SLPASR 325.1 1.3204999999999996e-187 19380000.0 34617.0 24031.0 38111.0 49029.0 43372.0 35214.0 30153.0 36913.0 30806.0 32845.0 True False 45624.48592166976 31798.550798182154 37605.62323871495 37726.12154049893 37350.54645521559 33012.06301326604 32836.55858589895 31208.944026355097 32434.342268304546 31695.10654723992 1.4394804401010237 1.0032637293958313 1.186480417179406 1.1902822123115469 1.178432588625204 1.0415507821077445 1.0360135100652763 0.984661275072219 1.0233233392026253 1.0 14.951972497359401 -6.803602878916805 3.0497627644526135 1.0117982893915733 1.1899489092543243 0.4581949035889026 0.09940603081234084 0.24980657674271572 4.753395408983382 0.035409000955029114 0.03212698456463055 1.5717994087882485e-07 6.803602878916805 0.17815061986275094 GGTPAFLPS(ph)SLSPQSSLPASR ddPTM_PC-9_Lapatinib_30min_R1 1 GGTPAFLPSSLSPQSSLPASR 21 0 Q96JY6;Q96JY6-3;Q96JY6-5;A0A087WVI1;E5RGS7;H0YBP7;B3KPU0 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 GGTPAFLPS(0.571)S(0.215)LS(0.192)PQS(0.005)S(0.017)LPASR 276.3 6.178199999999998e-101 14373000.0 29856.0 23999.0 29983.0 23570.0 26234.0 25483.0 26409.0 22253.0 26080.0 16622.0 True False 29430.247965080165 23943.43178999416 27517.913477726994 25303.416427215056 24690.96769802843 24393.15149377438 27776.328799770577 23286.9556185705 23142.595765424918 19495.090552577214 1.5096235580803465 1.2281775109184545 1.4115304262636101 1.297937876152619 1.2665223396340846 1.2512458676704967 1.4247858313281134 1.1945035882632518 1.187098654556673 1.0 14.250823235462258 -14.353052539860501 0.1084765794452803 2.447175165087317e-14 1.4960994635726732 0.6162466513619563 0.08522377851385503 110.70341167602619 0.8285724060600698 24.544862178891496 1.1015471575707787 4.435549805129971e-15 14.353052539860501 1.4960994635726488 GGTPAFLPSS(ph)LSPQSSLPASR ddPTM_PC-9_AZD4547_30min_R2 1 GGTPAFLPSSLSPQSSLPASR 21 0 Q96JY6;Q96JY6-3;Q96JY6-5;A0A087WVI1;E5RGS7;H0YBP7;B3KPU0 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 GGTPAFLPS(0.037)S(0.737)LS(0.225)PQSS(0.001)LPASR 207.1 1.3201999999999998e-78 0.0 6680.6 5239.8 7881.0 10612.0 9578.5 6708.7 6473.4 8059.9 5680.8 7779.5 True False 8804.891834887692 6933.462880126284 7776.49279064608 8165.567353765624 8248.690611945092 6289.203928468728 7049.5200593625295 6814.427653076683 5981.0754904169435 7507.14207289551 1.1728686828344037 0.9235822118192633 1.0358792620594006 1.0877065166046815 1.0987790735607548 0.8377627421193825 0.9390417806018055 0.9077259477584861 0.7967180362832854 1.0 12.874048070965527 -6.758790731014651 24.99999896270198 0.8931570715996316 1.0557564121723237 0.5354049530759096 0.07781663488000146 56.80780898494647 536197.2015180942 0.025694893472363107 0.02458977862905091 1.7426463820816217e-07 6.758790731014651 0.1625993405726921 GGTPAFLPSSLS(ph)PQSSLPASR ddPTM_PC-9_AZD4547_30min_R2 1 GGTPAFLPSSLSPQSSLPASR 21 0 Q96JY6;Q96JY6-3;Q96JY6-5;A0A087WVI1;E5RGS7;H0YBP7;B3KPU0 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 GGTPAFLPS(0.018)S(0.127)LS(0.854)PQSSLPASR 179.85 7.019100000000001e-13 20884000.0 21253.0 20271.0 28889.0 39097.0 32674.0 29099.0 28705.0 28704.0 21195.0 27753.0 True False 28011.011910138033 26823.204328989646 28505.91298426271 30083.7906926286 28137.7790942939 27279.43492994342 31259.68939104663 24268.45635230127 22315.32442954991 26781.375917355763 1.0459138468679423 1.0015618470000556 1.06439314664895 1.1233101236270948 1.050647255059779 1.0185972152485596 1.1672174531850203 0.9061691388519741 0.833240401778177 1.0 14.708942461875363 -7.791835643890285 22.583793107049832 0.9022777226707588 1.0643627110336131 0.586339712174325 0.059119997559299656 47.84030744114245 35542.702194695514 0.03151176286957188 0.015143310620609321 1.6149696166388553e-08 7.791835643890285 0.16208498836285434 GGTPAFLPSSLS(ph)PQSSLPASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GGTPAFLPSSLSPQSSLPASR 21 0 Q96JY6;Q96JY6-3;Q96JY6-5;A0A087WVI1;E5RGS7;H0YBP7;B3KPU0 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 GGTPAFLPS(0.275)S(0.165)LS(0.558)PQS(0.002)SLPASR;GGTPAFLPSS(0.007)LS(0.99)PQS(0.001)S(0.002)LPASR;GGTPAFLPS(0.001)S(0.003)LS(0.995)PQSSLPASR;GGTPAFLPS(0.008)S(0.039)LS(0.951)PQS(0.001)S(0.001)LPASR 282.18 1.9302999999999997e-102 42562500.0 142146.0 144457.0 161016.0 154709.0 175200.0 147613.0 151278.0 158328.0 137104.0 111630.0 True False 166208.51028852712 158797.73627694647 164855.23209658076 146041.15630334557 140870.81768372303 139871.91442216485 136947.85268212555 154172.05776238255 139108.88662471532 131867.63533740622 1.2604192822844955 1.2042207010888981 1.250156884020632 1.1074829387034502 1.0682743898704228 1.0606993449475173 1.038525126591682 1.1691425069381627 1.0549130290293074 1.0 17.00873099757309 -5.849038692483297 4.082239100740586 1.0733099687580137 1.2354105844716565 0.7636875837573917 0.04286975849932097 0.10611517986516938 3.3087469228627273 0.012121207459015211 0.018958320070845372 1.4156676486354511e-06 5.849038692483297 0.16210061571364287 GGTPAFLPSSLS(ph)PQSSLPASR ddPTM_PC-9_Lapatinib_30min_R1 3 GGTPAFLPSSLSPQSSLPASR 21 0 Q96JY6;Q96JY6-3;Q96JY6-5;A0A087WVI1;E5RGS7;H0YBP7;B3KPU0 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 GGTPAFLPSS(0.006)LS(0.991)PQS(0.001)S(0.002)LPASR;GGTPAFLPS(0.005)S(0.235)LS(0.676)PQS(0.01)S(0.072)LPAS(0.002)R;GGTPAFLPSS(0.002)LS(0.994)PQS(0.003)S(0.001)LPASR 273.8 1.4057999999999996e-186 17123400.0 66465.0 56067.0 71040.0 49954.0 60849.0 54879.0 52923.0 50102.0 57094.0 47234.0 True False 65517.19691181182 55937.18030624622 65199.36542233019 53627.783801658974 57269.98145373687 52531.953099197315 55663.093985772255 52429.92182634341 50663.472493526446 55398.33396465122 1.1826564487231201 1.0097267607711602 1.176919245693072 0.9680396496378031 1.0337852667244456 0.9482587171794211 1.00477920547737 0.9464169420654075 0.9145306161346656 1.0 15.757554969234064 -5.864384837813405 0.7703028930130058 0.9558186677457934 1.1403661026341183 0.5335803837603434 0.0596831962312039 0.6827532608041121 0.7531639227119634 0.02804493405782907 0.0847707266173978 1.3665173880699644e-06 5.864384837813405 0.18454743488832492 GGTSQVGS(ph)PTLLSPAVPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGTSQVGSPTLLSPAVPSK 19 0 Q8IY92;Q8IY92-2 Q8IY92 SLX4 Structure-specific endonuclease subunit SLX4 1 GGT(0.03)S(0.023)QVGS(0.667)PT(0.107)LLS(0.172)PAVPSK 132.01 2.5556e-06 0.0 18180.0 22020.0 21588.0 25709.0 30942.0 23559.0 25994.0 23856.0 21950.0 21441.0 True False 21257.51492863264 24206.000074889784 22102.73979294592 24268.60807970257 24879.137219005526 22323.524566750788 23531.66013973721 23229.805277521362 22270.977224679784 25328.08357313738 0.8392863545024808 0.9556980497554239 0.8726574092793891 0.9581699306078383 0.9822747602346037 0.8813744041190236 0.9290738508417813 0.9171560576402462 0.8792997370041876 1.0 14.62845030049536 -4.7496179483874466 24.80915690522084 0.9271193430168999 0.8392861373128093 0.2961651604173604 0.041932205163826466 641.8796459554802 1346994.2118200688 0.01002325060721871 0.158887530898655 1.7798444620162805e-05 4.7496179483874466 -0.08783320570409059 GGTSQVGS(ph)PTLLSPAVPSK ddPTM_PC-9_Lapatinib_30min_R1 2 GGTSQVGSPTLLSPAVPSK 19 0 Q8IY92;Q8IY92-2 Q8IY92 SLX4 Structure-specific endonuclease subunit SLX4 1 GGT(0.004)S(0.003)QVGS(0.592)PT(0.346)LLS(0.055)PAVPSK;GGT(0.076)S(0.055)QVGS(0.378)PT(0.116)LLS(0.076)PAVPS(0.298)K 136.02 3.057e-09 4155400.0 86500.0 84463.0 98360.0 73943.0 100875.0 99582.0 103798.0 101171.0 114074.0 88308.0 True False 85266.4941378428 84267.43111289121 90273.22048058004 79381.01488661689 94941.73082788053 95323.10999698 109172.15255248548 105871.77400289377 101225.78486752615 103571.92013698636 0.8232587947106472 0.8136127147342385 0.871599371346817 0.7664337475024691 0.9166744297325823 0.920356693888688 1.0540709529000925 1.0222053802117947 0.9773477669781813 1.0 16.660273394737906 -6.767260663535088 1.7500163801334445 1.0133876529019166 0.823303700171321 0.8362401494204931 0.03722209239052388 0.1284174448543103 0.8133732167891801 0.015078067835483839 0.013704094468747914 1.7089892718955126e-07 6.767260663535088 -0.19008395273059553 GGTSQVGSPT(ph)LLSPAVPSK ddPTM_PC-9_AZD4547_30min_R2 1 GGTSQVGSPTLLSPAVPSK 19 0 Q8IY92;Q8IY92-2 Q8IY92 SLX4 Structure-specific endonuclease subunit SLX4 1 GGT(0.009)S(0.007)QVGS(0.271)PT(0.483)LLS(0.093)PAVPS(0.137)K 148.38 0.00031364 5442300.0 28922.0 31237.0 43019.0 50338.0 40090.0 44019.0 30099.0 40486.0 30681.0 37399.0 True False 38118.59438502853 41333.74937717179 42448.53995188471 38733.35181434731 34524.19550377185 41266.48497134541 32777.752690510824 34229.81897572707 32302.7350234971 36089.67239336966 1.0562189085438087 1.1453068602741199 1.1761963225713097 1.0732530734045493 0.9566225796528588 1.1434430471285415 0.9082308183139036 0.9484657716653508 0.8950686687150895 1.0 15.1392984266747 -6.825045355834422 0.8602156334813374 0.9316781455109343 1.1230983269314474 0.5071615759524108 0.06880632076620856 0.4793091916516328 0.764636408955006 0.04550265776765984 0.03993670085925705 1.496079403883169e-07 6.825045355834422 0.1914201814205131 GGTTSWGTS(ph)GQPSPSYDSSR ddPTM_PC-9_AZD4547_30min_R2 1 GGTTSWGTSGQPSPSYDSSR 20 0 Q99081;Q99081-3;H0YNQ5 Q99081 TCF12 Transcription factor 12 1 GGTTSWGT(0.022)S(0.552)GQPS(0.423)PS(0.001)Y(0.002)DSSR 188.9 8.562999999999999e-12 13534000.0 13685.0 11887.0 18827.0 25449.0 24749.0 18306.0 16439.0 27105.0 16478.0 25722.0 True False 18036.545334316976 15729.240287045535 18577.341678656732 19582.126233130533 21313.02854883636 17161.32292613301 17902.039153437232 22916.54506093668 17348.99343949627 24821.48060916746 0.7266506627189449 0.633694683033379 0.7484380956628129 0.7889185396095248 0.8586525874272259 0.6913899777515575 0.7212317200298425 0.923254556074821 0.6989507883380923 1.0 14.599301554799894 -14.522878744377195 0.131879961805155 1.8043780525640316 0.6604339322436587 0.4842186280268653 0.07811394387320099 125.13718978059508 1.031772266221565 26.633397764259033 0.5723158157365094 3.000000006238688e-15 14.522878744377195 -1.143944120320373 GGTTSWGTS(ph)GQPSPSYDSSR ddPTM_PC-9_Lapatinib_30min_R1 1 GGTTSWGTSGQPSPSYDSSR 20 0 Q99081;Q99081-3;H0YNQ5 Q99081 TCF12 Transcription factor 12 1 GGTTSWGT(0.034)S(0.894)GQPS(0.069)PS(0.003)YDSSR 192.72 7.2586e-13 14006000.0 40706.0 30184.0 33855.0 32742.0 48278.0 50759.0 51070.0 40077.0 56385.0 41813.0 True False 40125.52497543385 30114.11080249943 31071.572584079204 35149.95590411014 45438.382958199945 48588.155895008174 53714.15471257088 41939.1237282816 50034.32753962745 49040.321337679634 0.8182149684366732 0.6140683825283493 0.6335923529156339 0.7167562313076246 0.9265514931136437 0.9907797210471367 1.095305928823516 0.855196756144787 1.0202691616782715 1.0 15.581680811897026 -6.298801265048748 2.916398069927591 0.9879667381491685 0.679167442041219 0.7801259663376524 0.07498380060091726 0.12046396485729564 2.0509566336686307 0.024299947974210007 0.029602995942451363 5.025725161728273e-07 6.298801265048748 -0.30879929610794943 GGTTSWGTSGQPS(ph)PSYDSSR ddPTM_PC-9_AZD4547_30min_R2 1 GGTTSWGTSGQPSPSYDSSR 20 0 Q99081;Q99081-3;H0YNQ5 Q99081 TCF12 Transcription factor 12 1 GGTTSWGT(0.029)S(0.052)GQPS(0.918)PS(0.001)YDSSR 135.91 9.9381e-05 4627800.0 7241.5 6965.3 10310.0 13484.0 11938.0 11379.0 7428.7 11938.0 9520.4 10744.0 True False 9544.146367442927 9216.697011134705 10173.282663565673 10375.472125723298 10280.61476487973 10667.469331173805 8089.839908701205 10093.256407949157 10023.628907718181 10367.85583021909 0.9205516091017291 0.8889684773847729 0.9812330370098032 1.000734606617697 0.9915854283886665 1.0288983089523134 0.7802809029348021 0.9735143479262548 0.966798639165333 1.0 13.339829941689208 -10.461944073975458 0.004641518275091549 1.94044556360716 1.2866635093131824e-06 0.03578119605166352 0.06812294636249468 138698.1666936316 125.43797692019479 26931.36158516484 25519.418137501732 3.4518818788615976e-11 10.461944073975458 -1.9404442769436507 GGTTSWGTSGQPS(ph)PSYDSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GGTTSWGTSGQPSPSYDSSR 20 0 Q99081;Q99081-3;H0YNQ5 Q99081 TCF12 Transcription factor 12 1 GGTTSWGT(0.023)S(0.077)GQPS(0.898)PS(0.001)YDSSR;GGTTSWGT(0.003)S(0.137)GQPS(0.826)PS(0.027)Y(0.006)DSSR 254.02 4.955199999999999e-66 12672000.0 10291.2 7928.299999999999 12974.9 12514.1 17100.4 16163.9 21727.9 21100.3 19458.5 17280.5 True False 12033.29689953489 8715.369227690671 13284.27082358226 11812.975548259607 13749.699376248536 15316.236629080317 19669.67601562653 20546.439482615846 19743.043750634686 20413.317857637277 0.5894826594802102 0.426945256448352 0.65076490339429 0.578689639315051 0.6735651437036891 0.7503060862470243 0.9635707508599575 1.0065213125032864 0.9671648620926254 1.0 14.31722306793387 -6.946602139966742 1.105424159974317 1.0106392585007276 0.5453997410342318 0.9214992111586984 0.055691601249497485 0.12193547249902623 0.3095107455750339 0.032348311658339464 0.024415600382168477 1.1308314023823167e-07 6.946602139966742 -0.4652395174664957 GGTTSWGTSGQPS(ph)PSYDSSR ddPTM_PC-9_Lapatinib_30min_R1 2 GGTTSWGTSGQPSPSYDSSR 20 0 Q99081;Q99081-3;H0YNQ5 Q99081 TCF12 Transcription factor 12 1 GGTTSWGT(0.006)S(0.207)GQPS(0.786)PSYDSSR;GGTTSWGT(0.014)S(0.377)GQPS(0.595)PS(0.014)YDSSR 204.78 4.8692e-21 13784600.0 29302.0 21806.4 27230.0 20565.4 29635.0 36106.0 36442.0 33889.0 41662.0 36300.0 True False 28884.148106671328 21755.90862058123 24991.254510839673 22077.84812016328 27891.92756465171 34561.83054719686 38328.788447924555 35463.606657876946 36969.58683969065 42574.406633290404 0.6784392406325591 0.5110090859979134 0.5870018277905521 0.5185708942541044 0.6551336770209275 0.8117982910458644 0.9002776897882576 0.8329794696456608 0.8683523685514586 1.0 15.377698802508469 -6.753881374488655 2.2902631917639678 0.8858630883683578 0.569916752461578 0.8631687075610165 0.059565252569326835 0.1009173839724238 1.0868770774198713 0.02191779111061302 0.0203272116651698 1.762457387682521e-07 6.753881374488655 -0.3159463359067798 GGTTSWGTSGQPSPS(ph)YDSSR ddPTM_PC-9_AZD4547_30min_R2 2 GGTTSWGTSGQPSPSYDSSR 20 0 Q99081;Q99081-3;H0YNQ5 Q99081 TCF12 Transcription factor 12 1 GGTTSWGT(0.011)S(0.039)GQPS(0.463)PS(0.487)YDSSR;GGTTSWGT(0.001)S(0.006)GQPS(0.153)PS(0.506)Y(0.334)DSSR 311.19 1.2806999999999997e-139 22990100.0 19259.8 20468.6 21387.8 32850.0 29413.0 22803.0 23842.6 30285.0 19237.5 23090.9 True False 25384.015771273513 27084.67466471105 21104.183797459747 25276.94002744071 25329.512655336526 21377.124805233852 25964.545210763583 25605.149130067042 20254.35497586536 22282.494619322955 1.1391909301421295 1.2155135736563236 0.947119438734593 1.1343855550859654 1.1367449241240366 0.9593685613053404 1.1652440920258373 1.149115014611638 0.90898058417127 1.0 14.443623137068435 -1.5228787924299332 0.09340884126281061 0.9392791186617593 1.5138962071864603 0.1662417807417177 0.09478216070131931 301.9291345174814 2.0258993401709295 1.555319963957722 22.213776659373682 0.029999996743021496 1.5228787924299332 0.5746170885247011 GGTTSWGTSGQPSPS(ph)YDSSR ddPTM_PC-9_Lapatinib_30min_R1 1 GGTTSWGTSGQPSPSYDSSR 20 0 Q99081;Q99081-3;H0YNQ5 Q99081 TCF12 Transcription factor 12 1 GGTTSWGTS(0.002)GQPS(0.275)PS(0.717)Y(0.007)DSSR 227.09 6.1372e-36 11874000.0 41208.0 29048.0 36877.0 38667.0 53410.0 57487.0 49376.0 47604.0 66693.0 50573.0 True False 40620.36636337833 28980.7411407038 33845.11540933656 41510.70016933069 50268.52880810012 55028.415018742235 51932.447681376485 49815.855626946046 59181.33203157532 59314.475665713326 0.6848305731017175 0.48859474547215953 0.5706046463275186 0.6998409697369357 0.8474917504355146 0.9277400567253324 0.8755442427588715 0.8398600015905063 0.9977552927402009 1.0 15.856096616235904 -6.160677672095236 1.8935281139274365 0.9151746364874972 0.5701143283217944 0.8470868544691555 0.06513016402972809 0.12358573555121553 0.8740027632287655 0.021595856879170504 0.03060605097669998 6.907522812989868e-07 6.160677672095236 -0.34506030816570277 GGTTSWGTSGQPSPSY(ph)DSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGTTSWGTSGQPSPSYDSSR 20 0 Q99081;Q99081-3;H0YNQ5 Q99081 TCF12 Transcription factor 12 1 GGTTSWGT(0.001)S(0.095)GQPS(0.187)PS(0.101)Y(0.616)DSSR 185.2 2.3428e-11 6850000.0 14930.0 12606.0 17845.0 18588.0 26790.0 25615.0 29265.0 22485.0 26803.0 17847.0 True False 17457.354119058597 13857.44036984835 18270.492477539367 17546.574623109096 21540.69181362412 24271.70430736964 26492.807339747986 21894.792574826766 27194.943168705788 21082.519823225743 0.8280487468023888 0.6572952610049098 0.8666180622968759 0.8322807126583966 1.0217323163568723 1.1512715041126396 1.2566243296288497 1.0385282574574495 1.2899284998535252 1.0 14.363759690509958 -6.330122358909829 1.6422230654456478 1.1597340839368677 0.7674658206928707 0.7516303594707204 0.09551967632595319 0.16951712957763715 0.9086615701446206 0.033342567275510084 0.042490664435511805 4.676033793080421e-07 6.330122358909829 -0.392268263243997 GGTVS(ph)PPPGTSR ddPTM_PC-9_AZD4547_30min_R2 2 GGTVSPPPGTSR 12 0 Q16584;Q16584-2;E9PID4 Q16584 MAP3K11 Mitogen-activated protein kinase kinase kinase 11 1 GGT(0.002)VS(0.664)PPPGT(0.116)S(0.219)R;GGTVS(0.992)PPPGT(0.006)S(0.001)R 82.20200000000001 0.01237 14926800.0 71495.0 74237.0 96207.0 129268.0 102802.0 90890.0 72424.0 106528.0 85962.0 87125.0 True False 94228.92281161783 98232.65846634124 94931.23231946286 99467.25977069125 88529.71679168755 85206.63393183799 78869.59569612118 90066.54536991208 90505.77582509878 84074.78026878618 1.1207751303110036 1.1683962557177368 1.1291285212517799 1.1830808174900425 1.0529877866901225 1.0134624635286977 0.9380886330475787 1.0712670920098786 1.0764913751276277 1.0 16.359385482792277 -6.407965548810765 4.290989859293874 1.0202937802694343 1.149653429848221 0.7067827252537744 0.03982311883215437 0.13615517294861249 4.157139768184899 0.013375010823048334 0.015140512971566494 3.9087190117769255e-07 6.407965548810765 0.12935964957878676 GGTVS(ph)PPPGTSR ddPTM_PC-9_Lapatinib_30min_R1 1 GGTVSPPPGTSR 12 0 Q16584;Q16584-2;E9PID4 Q16584 MAP3K11 Mitogen-activated protein kinase kinase kinase 11 1 GGT(0.004)VS(0.808)PPPGT(0.186)S(0.003)R 88.09200000000001 0.0082229 10273000.0 55492.0 65070.0 63977.0 60897.0 76052.0 68695.0 64663.0 68982.0 68606.0 58781.0 True False 54700.673904013514 64919.33441288889 58717.058018361706 65375.568526436786 71578.7708839849 65757.07498586633 68010.93374151112 72187.15555117202 60878.86982679218 68941.21752924086 0.7934393366466536 0.9416621397113255 0.85169743330189 0.9482798660860358 1.0382580036917006 0.9538136595567955 0.9865061305693481 1.04708269070755 0.8830547531448932 1.0 16.073079157046152 -5.907065376134879 4.425862762666469 0.9863510322890535 0.870818424257152 0.4986845484798611 0.054603620303632375 0.1770977450313263 6.23263449794794 0.01481318509995078 0.022526631808485544 1.2386101194194554e-06 5.907065376134879 -0.11553260803190157 GGVDHAAAFGR ddPTM_PC-9_AZD4547_30min_R2 2 GGVDHAAAFGR 11 0 I3L3Q4;F6TLX2;Q9HC38-2;Q9HC38 I3L3Q4 GLOD4 Glyoxalase domain-containing protein 4 0 ; 98.04 0.0043146999999999994 7461300.0 78872.0 75581.0 106036.0 140757.0 126514.0 97437.0 95110.0 118835.0 92428.0 91099.0 False True 103951.65536048598 100011.08018298884 104629.89335730851 108307.64832397178 108949.71489060114 91344.24898686893 103574.60574751622 100471.78130663726 97313.55538449828 87909.65173837772 1.1824828480705376 1.1376575632517052 1.1901980190831698 1.2320336411557997 1.2393373507477814 1.0390696263785995 1.1781937898668733 1.1428981837585352 1.1069723683368342 1.0 16.423733949362592 -6.751620271612976 24.99988386842876 1.1076558617844763 1.19472319062419 0.4646924424196849 0.054149098056881215 221.52397298758672 564009.1478203994 0.01817761037216685 0.01796076991809305 1.7716573421616302e-07 6.751620271612976 0.08706732883971369 GGVDHAAAFGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGVDHAAAFGR 11 0 I3L3Q4;F6TLX2;Q9HC38-2;Q9HC38 I3L3Q4 GLOD4 Glyoxalase domain-containing protein 4 0 82.831 0.011337 3393200.0 31289.0 29813.0 31823.0 35105.0 43893.0 36431.0 37128.0 30656.0 30389.0 28081.0 False True 36585.6097140807 32772.63761274699 32581.781009399565 33138.18066194559 35292.48173853692 34520.494226889845 33610.967056557776 29851.3124827169 30833.38163466032 33171.863010926296 1.1029109128429107 0.9879649388987346 0.9822113698789734 0.9989846108742939 1.0639282372205663 1.0406558780108108 1.0132372440307873 0.8998985819061276 0.929504068689307 1.0 15.017672419144413 -7.663840228073715 6.490784862672215 0.9365260662687002 1.0255568406798932 0.4626651334763825 0.04141506548804569 0.1821083559586271 10.216654847492947 0.020031172585952793 0.011395924910441677 2.1685017248439277e-08 7.663840228073715 0.089030774411193 GGVDHAAAFGR ddPTM_PC-9_Lapatinib_30min_R1 1 GGVDHAAAFGR 11 0 I3L3Q4;F6TLX2;Q9HC38-2;Q9HC38 I3L3Q4 GLOD4 Glyoxalase domain-containing protein 4 0 67.08 0.034074 4050100.0 45792.0 47351.0 43215.0 39904.0 46979.0 39758.0 40598.0 40133.0 45030.0 37964.0 False True 45138.99768277565 47241.36166873676 39662.0295147241 42838.67327584176 44215.787584267666 38057.643020424664 42699.96579246037 41997.72569271962 39958.24721307836 44526.026816149744 1.013766574528576 1.0609830934118325 0.8907605809629199 0.9621041071714044 0.9930324070197624 0.8547280263196766 0.958988907067112 0.9432174549534903 0.8974132674821407 1.0 15.442361261297139 -5.2538347707609105 24.99842553412988 0.9361716123293403 1.0373748415802495 0.4451540979318237 0.044566930174775476 491.5576056685574 1615873.709608234 0.010951194332601883 0.027797647741947425 5.573977730223646e-06 5.2538347707609105 0.10120322925090919 GGVGAPGS(ph)PSTPPTR ddPTM_PC-9_AZD4547_30min_R2 1 GGVGAPGSPSTPPTR 15 0 Q9ULR3 Q9ULR3 PPM1H Protein phosphatase 1H 1 GGVGAPGS(0.816)PS(0.053)T(0.13)PPTR 86.49799999999999 0.0054583 9259500.0 8856.2 9322.9 11311.0 15760.0 14535.0 12495.0 10988.0 15701.0 10083.0 14013.0 True False 11672.287379596495 12336.345105753911 11161.008749523893 12126.77548957277 12517.066142362786 11713.685674753197 11965.91071342346 13274.771223086766 10615.966795147524 13522.409135225249 0.8631810547124127 0.9122889998660301 0.8253713253247147 0.8967910501970453 0.925653559006465 0.8662425132692952 0.8848948877203262 0.981686849609261 0.7850647535499737 1.0 13.723064582783115 -11.839895789382345 2.4553845481483534 1.6857678045482918 0.8857780639788009 0.31957293015061927 0.051281433808053965 2879299.695434537 1630668.6704958638 10566461.5695013 0.012145019944408373 1.4457866511488756e-12 11.839895789382345 -0.7999897405694909 GGVPEHDPPTPPS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 1 GGVPEHDPPTPPSPAR 16 0 B7Z3A9 B7Z3A9 SLC6A9 Transporter 1 GGVPEHDPPT(0.004)PPS(0.996)PAR 64.22399999999999 0.030573000000000003 1115200.0 3034.1 5746.8 4594.4 5642.2 4965.6 4910.6 5084.8 5744.6 5176.3 6021.9 True False 2990.833177614205 5733.493637682338 4216.666166896869 6057.146209827442 4673.533170745217 4700.585085167699 5348.0660638825175 6011.5150876933485 4593.290585144517 7062.77739132263 0.4234641716569972 0.8117902235920025 0.5970266275243915 0.8576153366052975 0.6617132201401601 0.6655434292666318 0.7572185512250723 0.8511545465214763 0.6503518843433832 1.0 12.786019910189015 -14.522878745278739 0.08793236771867091 1.8946106052425984 0.46930156062853706 0.41243933616495265 0.11826467905246327 226.4275256340203 1.3838742583954733 38.746140656671386 2.8639602532063857 3.0000000000110447e-15 14.522878745278739 -1.4253090446140613 GGVT(ph)GSPEASISGSK ddPTM_PC-9_AZD4547_30min_R2 2 GGVTGSPEASISGSK 15 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GGVT(0.649)GS(0.333)PEAS(0.011)IS(0.006)GSK;GGVT(0.793)GS(0.206)PEAS(0.001)ISGSK 151.56 0.00035574 934223000.0 63180.0 77752.0 88772.0 108977.0 102004.0 88246.0 77968.0 111462.0 84695.0 84453.0 True False 83269.92577436227 102883.81347677001 87594.8252774057 83854.03632786626 87842.5053172049 82727.96366980969 84907.00095597003 94238.10904195228 89171.80479173067 81496.32617549239 1.021762939289443 1.262434987010608 1.0748315830676949 1.0289302630316957 1.077870738958794 1.0151127977433623 1.0418506568398331 1.156347941857183 1.0941818972269999 1.0 16.31444740419547 -5.490949622577238 24.90955066559526 1.0629933219808914 1.148732563066851 0.1833239519974157 0.06843002548362992 921.4946437004068 718904.1118607561 0.017251607150182126 0.03585971661245899 3.2288686432724617e-06 5.490949622577238 0.08573924108595965 GGVT(ph)GSPEASISGSK ddPTM_PC-9_Lapatinib_30min_R1 1 GGVTGSPEASISGSK 15 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GGVT(0.432)GS(0.432)PEAS(0.126)IS(0.01)GSK 89.171 0.011290999999999999 294540000.0 26607.0 36857.0 39409.0 36104.0 38778.0 36320.0 35364.0 29084.0 41493.0 27822.0 True False 26227.57930087377 36771.659880987354 36168.944143139226 38759.20859941334 36497.154280481314 34766.67826605525 37194.97488261908 30435.34881636204 36819.621399339565 32630.995629515273 0.80376276588847 1.1268935921687533 1.108422940991228 1.187803432033652 1.118481173386847 1.0654495088286002 1.1398663805702456 0.9327128464579476 1.1283634069086024 1.0 14.993955386833674 -10.483836208686517 14.778362784946129 1.000000000222745 1.0739675980446437 0.03115212268510492 0.10920899897530867 0.0 0.0 0.10323221356615872 0.025037489441152524 3.282190554361645e-11 10.483836208686517 0.07396759782189877 GGVTGS(ph)PEASISGSK ddPTM_PC-9_AZD4547_30min_R2 6 GGVTGSPEASISGSK 15 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GGVT(0.011)GS(0.931)PEAS(0.052)IS(0.006)GSK;GGVT(0.077)GS(0.92)PEAS(0.003)ISGSK;GGVT(0.002)GS(0.623)PEAS(0.373)IS(0.002)GSK;GGVTGS(1)PEASISGSK;GGVT(0.273)GS(0.726)PEASISGSK;GGVT(0.003)GS(0.99)PEAS(0.007)ISGSK 202.63 5.9112e-11 1314047400.0 190989.0 234546.0 266086.0 318450.0 288762.0 293149.0 256145.0 337511.0 248746.0 241785.0 True False 251719.529182014 310358.40770298505 262557.5257824959 245036.27250345462 248672.38069494118 274818.34668813355 278941.4087813839 285356.43018121325 261894.20573497654 233320.18074362687 1.078858795581872 1.3301824416294623 1.1253099708121483 1.0502146523394882 1.0657988516140546 1.1778593082357716 1.1955305704476793 1.2230250691206348 1.1224670103558119 1.0 17.83195157129856 GGVTGS(ph)PEASISGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 10 GGVTGSPEASISGSK 15 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GGVT(0.08)GS(0.92)PEASISGSK;GGVT(0.126)GS(0.874)PEASISGSK;GGVT(0.38)GS(0.62)PEASISGSK;GGVT(0.056)GS(0.747)PEAS(0.197)ISGSK;GGVTGS(0.944)PEAS(0.046)IS(0.01)GSK;GGVT(0.103)GS(0.897)PEASISGSK;GGVT(0.24)GS(0.724)PEAS(0.036)ISGSK;GGVT(0.013)GS(0.978)PEAS(0.01)ISGSK;GGVT(0.081)GS(0.891)PEAS(0.028)ISGSK;GGVT(0.008)GS(0.989)PEAS(0.003)ISGSK 226.39 2.3317e-24 2148478100.0 493756.0 589040.0 554766.0 530511.0 667856.0 444407.0 515589.0 438090.0 368395.0 368580.2 True False 577339.1386744746 647515.9983702586 567993.7254017718 500788.1886098673 536994.4110444091 421101.51458618836 466748.6773788943 426590.60169472324 373782.07994013303 435400.8725807426 1.325994445652863 1.4871720273141633 1.3045305169810855 1.1501772737421398 1.2333333368431103 0.9671581779113168 1.0719975699918665 0.9797651510576945 0.8584780221606407 1.0 18.731984773250595 -6.199946899013022 0.6768129965731849 0.9423581289019961 1.4465140856206127 0.8224761613980717 0.07882358245782392 0.33248078783070795 0.3190096489726104 0.048408939251882104 0.09739825375234824 6.310344960616661e-07 6.199946899013022 0.5041559567186166 GGVTGS(ph)PEASISGSK ddPTM_PC-9_Lapatinib_30min_R1 9 GGVTGSPEASISGSK 15 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GGVT(0.019)GS(0.602)PEAS(0.315)IS(0.061)GS(0.003)K;GGVT(0.087)GS(0.903)PEAS(0.01)ISGSK;GGVT(0.275)GS(0.725)PEASISGSK;GGVT(0.004)GS(0.924)PEAS(0.07)IS(0.003)GSK;GGVT(0.318)GS(0.671)PEAS(0.011)ISGSK;GGVT(0.308)GS(0.691)PEAS(0.001)ISGSK;GGVT(0.003)GS(0.977)PEAS(0.021)ISGSK;GGVT(0.059)GS(0.932)PEAS(0.007)IS(0.002)GSK;GGVT(0.1)GS(0.9)PEASISGSK 224.67 2.9611999999999997e-24 2221509200.0 468709.7 866528.0 794797.4 677269.0 808923.7 697102.9 705704.9 701829.8 762606.0 568663.0 True False 462025.813727169 864521.6076553207 729452.2257786863 727077.6215631537 761344.3983711845 667289.4339932294 742242.8466814049 734439.3746636506 676713.2816828081 666955.6418541818 0.6927384442580109 1.2962205481190505 1.0937042585782164 1.0901438955397824 1.1415217903466497 1.0005004712729015 1.1128818771484106 1.1011817406954674 1.014630118131244 1.0 19.34723128771315 -4.742623868389434 24.999650629338635 1.0966339907046994 0.692737123884553 0.6827658827551397 0.08215203290866262 724.8492133417449 963036.998320159 0.019689102357549178 0.6900303149388263 1.808739952377173e-05 4.742623868389434 -0.40389686682014636 GGVTGSPEASIS(ph)GSK ddPTM_PC-9_AZD4547_30min_R2 1 GGVTGSPEASISGSK 15 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GGVT(0.028)GS(0.171)PEAS(0.228)IS(0.573)GSK 179.65 2.8097e-05 308310000.0 68473.0 80222.0 87113.0 103420.0 95754.0 92314.0 101320.0 117070.0 83052.0 101750.0 True False 90245.98967312281 106152.19267328727 85957.82470137687 79578.11682307204 82460.20993435208 86541.5909867282 110337.28371715175 98979.52150097239 87441.95916598155 98187.76347028954 0.9191164609878315 1.0811142745440745 0.8754433512215266 0.8104687795149895 0.8398216541443432 0.8813887589252877 1.1237376208343772 1.0080637138753286 0.8905586202952922 1.0 16.583255621190098 -7.203968297581955 24.998205325538773 1.0062626946933375 0.9013139491705812 0.26372262423075554 0.08542588856150035 417.64442581860584 181662.79238828633 0.03557785776603507 0.027558484853619454 6.252183304945302e-08 7.203968297581955 -0.10494874552275635 GGVTGSPEASIS(ph)GSKGDLK ddPTM_PC-9_AZD4547_30min_R2 1 GGVTGSPEASISGSKGDLK 19 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GGVT(0.001)GS(0.007)PEAS(0.015)IS(0.565)GS(0.413)KGDLK 67.877 0.004174000000000001 16548000.0 37926.0 44334.0 83570.0 99215.0 137520.0 138140.0 119970.0 90742.0 109180.0 135900.0 True False 49985.67909019409 58664.09850137768 82461.80719633204 76342.51460646973 118427.72176798953 129502.0839624178 130647.09758731433 76719.9089437195 114951.03190461229 131142.1823647405 0.38115637690984067 0.44733202882210377 0.628796972182332 0.5821354596200127 0.9030482765538493 0.9874937386830948 0.9962248243204525 0.5850132090248544 0.8765374331266167 1.0 17.00077228280388 -5.849441145053159 1.351703526485778 0.8807468907143345 0.4192559952238361 0.6914168533778533 0.12611842360604666 0.2796212952980273 1.0323574880344095 0.0466424427342229 0.10163499123166764 1.4143563835716647e-06 5.849441145053159 -0.46149089549049843 GGVTGSPEASIS(ph)GSKGDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGVTGSPEASISGSKGDLK 19 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GGVT(0.01)GS(0.069)PEAS(0.352)IS(0.432)GS(0.137)KGDLK 55.843999999999994 0.014162000000000001 40071000.0 17902.0 22224.0 32320.0 50560.0 50756.0 28287.0 41939.0 33514.0 29731.0 31429.0 True False 20932.45501938294 24430.251846700743 33090.631374282566 47727.287117731656 40810.72615499464 26803.579923582478 37966.234307934064 32634.293011018206 30165.759629473996 37126.82890817288 0.5638093970038737 0.6580215053411904 0.8912862301309604 1.28552016213874 1.0992246673135828 0.7219463851835215 1.0226091326527595 0.8789948932006495 0.812505687035218 1.0 15.180174475948 -5.264356633060596 3.530176620027768 0.973041677769881 0.5928630771915431 0.4858436562628068 0.14771268032367582 0.20367796003475958 5.497915262295649 0.042131086295563884 0.11469356294797103 5.440557027977273e-06 5.264356633060596 -0.38017860057833797 GGVTGSPEASIS(ph)GSKGDLK ddPTM_PC-9_Lapatinib_30min_R1 1 GGVTGSPEASISGSKGDLK 19 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GGVTGSPEAS(0.05)IS(0.622)GS(0.328)KGDLK 57.768 0.012126999999999999 19951000.0 175570.0 193840.0 146500.0 186220.0 130030.0 116930.0 101080.0 97925.0 94511.0 111870.0 True False 173066.3396044051 193391.17538949416 134455.33550635347 199915.24001170925 122381.89104881603 111929.17647714325 106313.42781176156 102474.9529927883 83866.17593504877 131206.58044259463 1.3190370408298608 1.4739441782350733 1.024760610731565 1.5236677866105655 0.9327420212918394 0.8530759364322766 0.810275120753381 0.7810199202441911 0.6391918427577786 1.0 17.00148055212015 -6.424223688775821 4.68958565797352 0.8101167442994432 1.321347246295853 0.7318154823401315 0.14907808374116407 0.11555575413377245 4.164657904247572 0.04582176773593785 0.051691814730094945 3.765098229649618e-07 6.424223688775821 0.5112305019964098 GGVTGSPEASISGS(ph)KGDLK ddPTM_PC-9_AZD4547_30min_R2 3 GGVTGSPEASISGSKGDLK 19 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GGVTGSPEAS(0.013)IS(0.292)GS(0.695)KGDLK;GGVTGS(0.002)PEAS(0.001)IS(0.147)GS(0.85)KGDLK;GGVTGSPEAS(0.02)IS(0.429)GS(0.551)KGDLK 90.37799999999999 0.00047218 79956000.0 76362.0 105356.0 145160.0 183269.0 245942.0 249755.0 202372.0 181696.0 217826.0 230760.0 True False 100643.5275717289 139410.26665112877 143235.0835541409 141019.16352782422 211797.1985679381 234137.78036798583 220382.7159534881 153619.05815871453 229339.83765940752 222681.16263787774 0.4519624667821345 0.6260532547956765 0.6432294580169253 0.6332783692042618 0.9511231038090139 1.051448526648564 0.9896783066103919 0.689861038710888 1.0299022824501687 1.0 17.764619995210182 -6.2182149089214365 4.228588974810974 0.9445915556088654 0.588514478808214 0.7389322904212676 0.10599502693965276 0.12336028739757293 4.903776787470904 0.033642186681196465 0.042954096310959304 6.050413982991592e-07 6.2182149089214365 -0.3560770768006515 GGVTGSPEASISGS(ph)KGDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGVTGSPEASISGSKGDLK 19 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GGVTGSPEAS(0.007)IS(0.319)GS(0.674)KGDLK 63.883 0.0056624 42434000.0 14234.0 21825.0 23058.0 35691.0 41062.0 32694.0 28991.0 26494.0 26329.0 21670.0 True False 16643.5350656852 23991.641763599884 23607.790167951956 33691.34898178324 33016.195866033355 30979.469085502373 26244.76260333621 25798.560572713406 26714.01181542568 25598.59946037438 0.650173658580374 0.9372247806266901 0.9222297573152736 1.3161403237679512 1.2897657122664512 1.2102017195689696 1.0252421287329436 1.0078114083017924 1.0435731789458997 1.0 14.643777259819833 -4.930456536957424 1.4891760667916154 1.1260627075371643 0.5657054257934451 0.5774819384500111 0.12106118774769328 0.6654156970367129 1.7057954848056776 0.038803173463726234 0.5112133169501033 1.1736631337149174e-05 4.930456536957424 -0.5603572817437192 GGVTGSPEASISGS(ph)KGDLK ddPTM_PC-9_Lapatinib_30min_R1 2 GGVTGSPEASISGSKGDLK 19 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GGVTGSPEAS(0.002)IS(0.352)GS(0.646)KGDLK;GGVTGSPEAS(0.006)IS(0.42)GS(0.575)KGDLK 114.21 0.00039063 63612400.0 78789.0 77257.0 51795.0 75517.0 61007.0 42570.0 35536.0 39544.0 42605.0 43811.0 True False 77665.45441186709 77078.11616315576 47536.61503448188 81070.77209732715 57418.68820437685 40749.38033551684 37375.88020101661 41381.35860246942 37806.376249460416 51383.672975511996 1.5114811751367063 1.500050730119838 0.9251307328134462 1.577753543152962 1.11745005522943 0.7930414074318285 0.7273882546082079 0.8053406112519556 0.7357663253749467 1.0 15.649022399296989 -6.597152040562453 3.5187290953289327 0.7948892405624798 1.3563123696645112 0.679373252722987 0.18275079744709455 0.1389243039205356 3.449161535335113 0.062129525526405105 0.06295450628022216 2.528412678764279e-07 6.597152040562453 0.5614231291020314 GGVVGIK ddPTM_PC-9_Lapatinib_30min_R1 1 GGVVGIK 7 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8;H3BU78 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 113.82 0.041149 14503000.0 119860.0 84362.0 93107.0 89434.0 80415.0 78480.0 68942.0 59127.0 80471.0 81270.0 False True 118150.7744203682 84166.66497218564 85452.1018634135 96011.27470307836 75685.14780197297 75123.59334581548 72511.47942420325 61874.25627372572 71407.50858280322 95317.41121453185 1.2395508114928244 0.8830145919799572 0.8965004480774829 1.0072795041294693 0.7940327673359451 0.788141352021553 0.760736978693231 0.6491390763274583 0.7491549305937991 1.0 16.540452148548525 -1.52287874528913 0.5252237494323777 0.7759876915383083 16.373224279698082 0.559738688164884 0.10709707103852235 88.79350489079144 0.8776420155487796 0.056351507882920614 1546.3572958997688 0.029999999999392644 1.52287874528913 15.597236588159774 GGWDHGDTQS(ph)IQSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GGWDHGDTQSIQSSR 15 0 Q9P206-2;Q9P206;Q9P206-3;Q9P206-4 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 GGWDHGDT(0.007)QS(0.988)IQS(0.002)S(0.002)R 101.01 0.0091536 0.0 2304.4 8757.3 8856.9 7448.6 6832.4 5735.4 7314.1 8771.8 5815.8 4099.3 True False 2694.489406025362 9626.66686902054 9068.082085980297 7031.27909068702 5493.640266793787 5434.625527405341 6621.255498501651 8541.549544490352 5900.8450725873645 4842.470639959055 0.5564286510672876 1.9879659753810996 1.8726147787355447 1.45200242055499 1.1344705368911103 1.1222836298809842 1.367330024443398 1.7638825673009293 1.2185608362588356 1.0 12.241527586414957 -6.008083825685017 24.304393852615465 1.3027068862177453 1.5469675798584068 0.04149912396093158 0.4072002269902079 802.4294705918486 2412562.207592551 0.11703106350249957 0.16493353526029514 9.81558468468512e-07 6.008083825685017 0.2442606936406615 GGWDHGDTQSIQSS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 GGWDHGDTQSIQSSR 15 0 Q9P206-2;Q9P206;Q9P206-3;Q9P206-4 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 GGWDHGDT(0.035)QS(0.057)IQS(0.223)S(0.685)R 62.589 0.02409 3563300.0 7787.7 8590.6 12201.0 16941.0 20559.0 16845.0 12507.0 14837.0 13829.0 13309.0 True False 10264.026605777155 11367.343451660918 12039.20676800822 13035.514185840884 17704.737724171748 15791.679487092239 13620.098770730543 12544.28257034191 14559.972707536952 12843.055960944319 0.7991888096563636 0.8850964666220379 0.9374098193311156 1.0149853917542546 1.3785455562921927 1.2295889339044128 1.0605029528913685 0.9767365811134844 1.133684440199729 1.0 13.648700907175256 -5.780193301482586 2.6497070116532946 1.1329496156547374 0.858933894143981 0.5073767871332071 0.11283926286521015 0.2394409937168507 3.4293517752400087 0.036315740504498005 0.06441117565316559 1.6588484011001032e-06 5.780193301482586 -0.27401572151075637 GGYFDEFGIIR ddPTM_PC-9_AZD4547_30min_R2 2 GGYFDEFGIIR 11 0 P11413;P11413-2;P11413-3;E7EUI8;E7EM57 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ; 172.59 0.00045043 17390200.0 53067.0 57307.0 59333.0 77203.0 76518.0 69570.0 65136.0 78044.0 53512.0 57990.0 False True 69941.2021378296 75830.3670505356 58546.205652506505 59405.04112445975 65894.79649682256 65219.77690216734 70932.9778148481 65984.0930727076 56340.53507308677 55959.78775078229 1.2498475235344662 1.3550867524417214 1.0462192228684437 1.0615665911568668 1.1775383564763677 1.165475773293218 1.2675705299446296 1.179134084042075 1.0068039450757058 1.0 15.77210287008152 -14.522871441506794 0.03026132763822652 9.214561148968574e-09 1.838808244774662 0.3109186101057463 0.09438713706531249 2127.659034134684 4.828314525103859 229.96095059678728 92.1961288273281 3.0000504531044992e-15 14.522871441506794 1.838808235560101 GGYFDEFGIIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GGYFDEFGIIR 11 0 P11413;P11413-2;P11413-3;E7EUI8;E7EM57 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ;;; 128.86 0.0013304999999999999 16932600.0 75210.1 78645.0 84134.0 86387.0 94164.0 85075.0 83102.0 69992.4 77001.0 69548.0 False True 87941.68446281366 86452.35585330197 86140.07363997183 81547.01646043287 75713.24016193004 80613.51723402191 75229.97695362182 68155.1736630779 78126.99395341978 82156.50185833487 1.070416613093561 1.0522886673336527 1.0484876022168759 0.9925814100635278 0.9215733198144784 0.9812189590670063 0.9156910926337068 0.8295773568913644 0.9509532682895468 1.0 16.32608713400164 -5.987609093348908 1.164525000962289 0.9192794972545251 1.0699511115061153 0.6081420813901275 0.044056519416549624 0.3199708298309558 0.8816532839211237 0.017087988066173905 0.034172658353647446 1.0289420278673157e-06 5.987609093348908 0.15067161425159026 GGYFDEFGIIR ddPTM_PC-9_Lapatinib_30min_R1 4 GGYFDEFGIIR 11 0 P11413;P11413-2;P11413-3;E7EUI8;E7EM57 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ;;; 185.81 0.0015274000000000002 53113800.0 113185.0 92768.0 101434.0 95133.0 104775.0 114862.0 103651.0 101671.0 103336.0 97127.0 False True 111570.96114441287 92553.20139564907 93094.48806656309 102129.39817438493 98612.34049557567 109949.62001639979 109017.54161176183 106395.00582823358 91697.21150367903 113915.27253640765 0.9794205698691936 0.812474037369035 0.8172256976061733 0.8965382419793104 0.8656639123086756 0.9651877010719486 0.9570054935076375 0.9339836833048829 0.8049597693265611 1.0 16.79760165550791 -6.740601750857903 24.69863381704909 0.9296499440674911 0.8689002723245931 0.16579491888558628 0.06431956325053419 380.6263263466948 451151.2397754342 0.021179739850277258 0.021155975369634338 1.817181258804657e-07 6.740601750857903 -0.060749671742898026 GGYLS(ph)DGDSPELTTK ddPTM_PC-9_AZD4547_30min_R2 2 GGYLSDGDSPELTTK 15 0 Q5VT97-2;Q5VT97 Q5VT97-2 SYDE2 Rho GTPase-activating protein SYDE2 1 GGYLS(0.999)DGDS(0.001)PELTTK;GGYLS(1)DGDSPELTTK 157.35 2.6792e-14 4495600.0 32397.0 32163.0 40846.0 54744.0 46482.0 45950.0 34491.0 49421.0 43658.0 35597.0 True False 42698.57210053832 42559.06076825486 40304.355351697704 42123.61658636877 40028.77663772321 43076.73923608717 37560.63218207943 41784.120031601225 45965.67275042652 34350.75986488353 1.2430168144311906 1.2389554389963466 1.1733177231080842 1.2262790328964852 1.1652952305909328 1.2540258033745604 1.0934439974493062 1.2163958001498756 1.338126810912757 1.0 15.068054392455245 -11.461257533807215 2.4368865244751685 0.8498682725508462 1.2121847942905823 0.5297815891963056 0.061077316897442065 21660404.28487713 9722992.197890934 18455869.15794183 0.0165202329127295 3.4573429883306166e-12 11.461257533807215 0.36231652173973616 GGYLS(ph)DGDSPELTTK ddPTM_PC-9_Lapatinib_30min_R1 2 GGYLSDGDSPELTTK 15 0 Q5VT97-2;Q5VT97 Q5VT97-2 SYDE2 Rho GTPase-activating protein SYDE2 1 GGYLS(1)DGDSPELTTK;GGYLS(1)DGDSPELTTK 180.27 2.3183e-05 8893600.0 68772.0 62728.0 67267.0 54674.0 68625.0 63039.0 57393.0 55694.0 65955.0 47541.0 True False 67791.29866875971 62582.75716999685 61736.566918128985 58694.90834711733 64588.61242194108 60342.96892108638 60364.528713894244 58281.74656094303 58526.45336305984 55758.39850559937 1.2158042642123585 1.1223915831031654 1.1072155688246548 1.0526648885229921 1.158365630165202 1.0822220605031656 1.0826087249947165 1.0452550310441622 1.0496437295842078 1.0 15.766901504220453 -1.5228787452803376 0.13882188531073958 0.9831072112161037 1.6451551433871632 0.6761938201337496 0.03369358471115755 49.198577376203296 0.45750379908245087 0.153681099513052 6.449547512271196 0.029999999999999995 1.5228787452803376 0.6620479321710595 GGYNGLNQCLIT(ph)TQSK ddPTM_PC-9_Lapatinib_30min_R1 1 GGYNGLNQCLITTQSK 16 0 M0R0N1;Q9Y2Q1-4;Q9Y2Q1-3;Q9Y2Q1-2;Q9Y2Q1 M0R0N1 ZNF257 Zinc finger protein 257 1 GGYNGLNQCLIT(0.498)T(0.498)QS(0.004)K 82.48299999999999 0.02617 0.0 19864.0 22367.0 24420.0 18156.0 25814.0 22387.0 21702.0 23502.0 23209.0 20856.0 True False 19580.735717388532 22315.210585724373 22412.281863925993 19491.252806640507 24295.67127227668 21429.560196645874 22825.62337129847 24593.988718269182 20594.958018395184 24460.93181112684 0.8004901803651489 0.912279661217713 0.9162480823290242 0.7968319832269957 0.9932438984693548 0.8760729297686832 0.9331461101950131 1.005439568213089 0.8419531266191137 1.0 14.57819174227355 -1.5228787452807087 0.11777114929851366 1.0142403873387145 0.4854568191463239 0.2680076428447308 0.06358874510034648 136.6116493239531 1.114095655132288 0.4518331729779021 11.81910062377233 0.029999999999974367 1.5228787452807087 -0.5287835681923906 GHAVGDIPGVR ddPTM_PC-9_AZD4547_30min_R2 2 GHAVGDIPGVR 11 0 D6RD47;P62266 D6RD47 RPS23 40S ribosomal protein S23 0 ; 112.13 0.0012165 1770100.0 15016.0 16924.9 21327.3 26371.0 21356.3 24355.0 17753.6 22558.8 17608.8 19902.6 False True 19790.77564779713 22395.542940541516 21044.486066989728 20291.573377888537 18391.346381571548 22832.077999889083 19333.636006719593 19072.855809653505 18539.565218922307 19205.81603187996 1.030457420551472 1.1660813007563382 1.0957350644230757 1.056532736969172 0.9575925517063965 1.1888106166376815 1.006655274351658 0.9930770855033834 0.9653099450785254 1.0 14.229255643087022 -7.498970000042452 24.754743157940162 0.9874893159080704 1.0815431982199954 0.34739428809295103 0.06175200919860357 764.8644600469522 791931.4407142196 0.026036533272575654 0.017436795549651253 3.169786416259694e-08 7.498970000042452 0.09405388231192502 GHAVGDIPGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GHAVGDIPGVR 11 0 D6RD47;P62266 D6RD47 RPS23 40S ribosomal protein S23 0 ; 86.189 0.012213 0.0 19690.3 24399.7 20621.4 21840.4 26110.0 20564.5 22829.5 17520.6 21216.4 16799.1 False True 23023.478888847927 26821.940964000383 21113.092383094998 20616.753195532157 20993.932932203286 19486.061418266756 20666.9244887332 17060.702814610195 21526.64971251463 19844.643848397573 1.1601860464080358 1.351595985743338 1.0639189367361637 1.0389076948436609 1.0579143214957982 0.9819305182360443 1.0414358981001326 0.8597132276570346 1.0847586823410227 1.0 14.276462050087682 -5.419060575918948 4.734014485385941 1.0083231348438617 1.2539285584406878 0.6441680896973977 0.0721105296176583 0.12412550980386843 4.398459569774851 0.01845023304912119 0.03967552739847339 3.8101267557905904e-06 5.419060575918948 0.24560542359682613 GHAVGDIPGVR ddPTM_PC-9_Lapatinib_30min_R1 2 GHAVGDIPGVR 11 0 D6RD47;P62266 D6RD47 RPS23 40S ribosomal protein S23 0 ; 112.13 0.0014487 10622800.0 36696.0 33198.0 32450.0 36769.0 33115.0 36057.0 35192.0 36764.0 35108.0 34771.0 False True 36172.70831077778 33121.13207067905 29782.086260622367 39473.11491778832 31167.240806594964 34514.9261629723 37014.069564221536 38472.189653580484 31153.767336370296 40781.12102055483 0.8869964190671885 0.812168259278235 0.7302910149431979 0.9679261856949142 0.7642565978234341 0.8463456937727584 0.9076275648618244 0.9433823468018308 0.7639262128343143 1.0 15.31561381327979 -14.522878743409702 0.18862788150407178 1.6399304151502607 0.8207581552587064 0.2518936485699351 0.07679940421702236 187.8570876214266 1.8285317386659912 45.21759428446968 0.20748095060127872 3.0000000129218913e-15 14.522878743409702 -0.8191722598915543 GHDGGHSHGGDMSNRPVCR ddPTM_PC-9_AZD4547_30min_R2 1 GHDGGHSHGGDMSNRPVCR 19 1 Q96QC0 Q96QC0 PPP1R10 Serine/threonine-protein phosphatase 1 regulatory subunit 10 0 50.178000000000004 0.012098000000000001 700420.0 0.0 0.0 0.0 2449.1 2326.5 0.0 0.0 1111.0 503.77 716.69 False True 0.0 0.0 0.0 1884.4978332178075 2003.505633313175 0.0 0.0 939.3204782402006 530.3982537331617 691.5989012434582 0.0 0.0 0.0 2.7248421445285413 2.8969184735704148 0.0 0.0 1.3581867706142277 0.7669159866788883 1.0 9.433791766719244 -5.616135521534539 24.42651961856709 1.2392730091515456 7.926846878738848e-05 0.28262119885284653 0.9121872525920969 19.81052303895628 5176.19319730314 0.2752774925186184 0.4767945572624493 2.420273682810212e-06 5.616135521534539 -1.2391937406827582 GHEDDSYEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GHEDDSYEAR 10 0 Q9H2P0;A0A669KBJ7;A0A2R8Y6X0 Q9H2P0 ADNP Activity-dependent neuroprotector homeobox protein 0 156.16 0.00026373 2781500.0 4302.9 3464.7 5072.1 3483.6 4565.6 3723.5 4939.7 5571.8 2934.6 3606.7 False True 5031.295983851121 3808.652518595399 5193.038100046367 3288.425185983582 3671.0034544338287 3528.233105152875 4471.775855668996 5425.546153810088 2977.5129732822456 4260.56615937851 1.180898452374939 0.8939310824247284 1.2188610400087947 0.7718282178871894 0.8616233892655523 0.8281136762508435 1.0495731525786929 1.2734331426510495 0.6988538287870588 1.0 12.056829438365776 -5.755801154892034 24.99946056087678 0.9359591520136122 1.0775002249416041 0.16871449301150587 0.17192562811051007 308.0206722913912 1365721.527229883 0.047664670266127016 0.07969252871292293 1.7546837135415363e-06 5.755801154892034 0.1415410729279919 GHEEEGT(ph)DASPSSCGSLPITNSFTK ddPTM_PC-9_AZD4547_30min_R2 1 GHEEEGTDASPSSCGSLPITNSFTK 25 0 Q9BXL7 Q9BXL7 CARD11 Caspase recruitment domain-containing protein 11 1 GHEEEGT(0.491)DAS(0.412)PS(0.088)S(0.008)CGS(0.001)LPITNSFTK 79.78399999999999 0.00018256 11265000.0 32715.0 32702.0 59773.0 105480.0 93887.0 98802.0 57973.0 103370.0 61183.0 92635.0 True False 43117.68948572746 43272.281977535364 58980.37096501557 81163.21564975477 80852.410657586 92623.89532108569 63132.484691417754 87396.54170629122 64417.008472429894 89391.87684589965 0.4823446045333284 0.4840739841734315 0.6597956441466187 0.907948445804197 0.9044715639762816 1.0361556171458133 0.7062440897202574 0.9776787868203266 0.7206136703391597 1.0 16.447856117372005 -5.550639938614236 2.6291280026865564 0.8921071997164643 0.48300448346911734 0.724305890768692 0.10287994491764833 0.1365107719467481 1.8894244280171815 0.027949461005906454 0.06116385147186123 2.8142330652480287e-06 5.550639938614236 -0.409102716247347 GHEEEGTDAS(ph)PSSCGSLPITNSFTK ddPTM_PC-9_AZD4547_30min_R2 1 GHEEEGTDASPSSCGSLPITNSFTK 25 0 Q9BXL7 Q9BXL7 CARD11 Caspase recruitment domain-containing protein 11 1 GHEEEGT(0.014)DAS(0.985)PS(0.001)S(0.001)CGSLPITNSFTK 91.1 3.0214999999999998e-06 11235000.0 28384.0 26569.0 41128.0 77888.0 70464.0 68572.0 42317.0 74285.0 44088.0 58978.0 True False 37409.52157612372 35156.909664887055 40582.615847442205 59932.12495760433 60681.289897175804 64284.18199993409 46083.13102110852 62805.96014948092 46418.40167256413 56913.198171506054 0.657308370958022 0.6177285901056353 0.7130615946963272 1.0530444059214672 1.0662076960481948 1.1295127328149055 0.8097090394083727 1.1035394630295985 0.815599951573338 1.0 15.796475631881187 -5.676928965880805 4.7601386428964245 1.001606523866515 0.645261971703309 0.6882288003696243 0.10353603293278987 0.11120510813543277 4.434318095987844 0.027863032204247077 0.04902646487645109 2.1041225663365997e-06 5.676928965880805 -0.35634455216320604 GHEEEGTDAS(ph)PSSCGSLPITNSFTK ddPTM_PC-9_Lapatinib_30min_R1 2 GHEEEGTDASPSSCGSLPITNSFTK 25 0 Q9BXL7 Q9BXL7 CARD11 Caspase recruitment domain-containing protein 11 1 GHEEEGT(0.01)DAS(0.652)PS(0.166)S(0.166)CGS(0.006)LPITNSFTK;GHEEEGT(0.149)DAS(0.845)PS(0.004)S(0.002)CGSLPITNSFTK 95.713 1.4558e-06 17511500.0 68384.0 68700.0 91249.0 69088.0 129539.0 119270.0 111922.0 96043.0 127000.0 93043.0 True False 67408.83161991028 68540.92937091526 83746.85945132624 74168.96199081176 121919.77070347297 114169.1001319497 117716.77352144798 100505.5084022094 112695.92263071174 109125.35857799537 0.6177192221708123 0.6280935088238622 0.7674371983068417 0.6796675214386658 1.1172450866801324 1.0462197019984993 1.078729775144904 0.9210096508445826 1.032719837984902 1.0 16.735626868890343 -6.252524162917851 24.812172291400394 1.0316865646996989 0.6767344745993401 0.8931546663735039 0.06089611062899124 187.7785537163737 522611.0307242947 0.019040149200691785 0.02420786628189796 5.590824209390416e-07 6.252524162917851 -0.3549520901003588 GHEEFPLDGR ddPTM_PC-9_AZD4547_30min_R2 1 GHEEFPLDGR 10 0 H0YIQ2;P49750-3;P49750-1;P49750 H0YIQ2 YLPM1 YLP motif-containing protein 1 0 78.513 0.019349 0.0 8410.3 10197.0 9978.6 14716.0 14231.0 11797.0 9255.9 13136.0 8431.1 11215.0 False True 11084.600454892667 13492.980836796782 9846.277244098583 11323.45355993356 12255.271294940821 11059.331725095117 10079.657168945774 11106.133035250476 8876.75073356821 10822.36626358033 1.0242307629335012 1.2467680827069827 0.9098081698854987 1.0463010846379779 1.132402193426269 1.0218959011128859 0.9313727629849363 1.026220399934632 0.8202227236977231 1.0 13.4017283522354 -7.074929204798854 4.140515129008752 0.9475760245144066 1.0718926289775002 0.2871462792502162 0.0943780965389138 0.31209921404702556 10.092931552208524 0.03634191810997121 0.028325236862945927 8.415323103085968e-08 7.074929204798854 0.12431660446309356 GHEEFPLDGR ddPTM_PC-9_Lapatinib_30min_R1 1 GHEEFPLDGR 10 0 H0YIQ2;P49750-3;P49750-1;P49750 H0YIQ2 YLPM1 YLP motif-containing protein 1 0 78.488 0.019377000000000002 0.0 6752.5 5629.6 6982.4 6616.4 4730.5 5613.4 6085.6 7959.9 7555.4 4850.9 False True 6656.208111743154 5616.565007081591 6408.334024843443 7102.99212766337 4452.261290520835 5373.32796747452 6400.682590930511 8329.746013043608 6704.431290110865 5689.371601582047 1.1699373108081494 0.9872030516550877 1.1263693907885142 1.2484669002264217 0.7825576535170935 0.9444501684474881 1.1250245262852347 1.4640889357143327 1.1784133221754332 1.0 12.474053598468759 -7.5300679200728915 24.991420591735878 1.2516620539278607 1.0412927009134374 0.17420501980917324 0.1611772207462913 253.35724551108467 880719.6949673997 0.0756544734484194 0.043801935289170583 2.950747717987632e-08 7.5300679200728915 -0.21036935301442328 GHFRQY(ph)PAHVSQPANHVTSMAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GHFRQYPAHVSQPANHVTSMAK 22 1 A0A0G2JN84;P59817 A0A0G2JN84 ZNF280A Zinc finger protein 280A 1 GHFRQY(0.998)PAHVS(0.002)QPANHVTSMAK 48.848 0.039572 0.0 5223.5 6032.9 6010.4 7890.0 5858.7 6983.4 6223.5 5872.2 5793.8 4902.3 True False 6107.735381172311 6631.806441952889 6153.71073056893 7447.948879725135 4710.729792029849 6617.178210426907 5633.965025761889 5718.060972110196 5878.523364207273 5791.048183414549 1.0546856437259056 1.1451823973674153 1.0626246813475044 1.2861141271550662 0.8134502844444099 1.1426563898014832 0.972874831519699 0.9873965456696792 1.0151052414040087 1.0 12.49960878523419 -6.254343036390628 24.999389568497055 0.9948688817689367 1.132401959244615 0.36797300555632617 0.0950940377820317 646.2711203657113 2276716.366077181 0.026788899924417534 0.033821607742534794 5.567458181243498e-07 6.254343036390628 0.13753307747567833 GHLS(ph)EGLVTK ddPTM_PC-9_AZD4547_30min_R2 2 GHLSEGLVTK 10 0 Q16659 Q16659 MAPK6 Mitogen-activated protein kinase 6 1 GHLS(1)EGLVTK;GHLS(1)EGLVTK 69.229 0.022061 10312400.0 68017.0 61370.0 84690.0 109492.0 89907.0 85756.0 69229.0 94771.0 63688.0 82632.0 True False 89644.99115851217 81206.65234424038 83566.95526453695 84250.31103453695 77424.96495778553 80393.6637634361 75390.24688565661 80126.31957092883 67054.41765837098 79739.07883122347 1.1242290790473723 1.018404696097922 1.0480050245051815 1.0565749224776224 0.9709789239183962 1.0082090857056192 0.94546172329415 1.0048563482972384 0.8409229030636162 1.0 16.28299931855284 -6.229885616865592 0.5775752153449328 0.9395123639324305 1.0916713932514688 0.5065710836759526 0.04989773480886964 0.892878547618706 0.6048478285281996 0.03478604438383993 0.07344446213947188 5.889987635972934e-07 6.229885616865592 0.15215902931903824 GHLS(ph)EGLVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GHLSEGLVTK 10 0 Q16659 Q16659 MAPK6 Mitogen-activated protein kinase 6 1 GHLS(1)EGLVTK;GHLS(1)EGLVTK 79.492 0.017712000000000002 0.0 63362.0 64647.0 66710.0 71823.0 66173.0 70144.0 73679.0 61541.0 61438.0 54337.0 True False 74087.9351434555 71064.72692286102 68300.61939908392 67798.99016330765 53206.87567685512 66465.52515854516 66699.59173023395 59925.61395807941 62336.41452072326 64187.867968544655 1.1542358001322366 1.1071364289227736 1.0640736569183873 1.0562586405975134 0.8289241777422677 1.0354842318663189 1.0391308177258696 0.93359720231627 0.9711557104727532 1.0 15.970013021513843 -5.736977178265478 2.035276836079708 0.9716237767401976 1.12489344733129 0.524646900265757 0.0601949457669985 0.2641827007769612 2.229511194470702 0.01860960987826392 0.03738992044310994 1.8324107111655183e-06 5.736977178265478 0.1532696705910923 GHLSRPEAQSLS(ph)PYTTSANR ddPTM_PC-9_AZD4547_30min_R2 1 GHLSRPEAQSLSPYTTSANR 20 1 O94776;O94776-2 O94776 MTA2 Metastasis-associated protein MTA2 1 GHLSRPEAQS(0.104)LS(0.517)PY(0.127)T(0.156)T(0.048)S(0.048)ANR 71.263 0.0018032 6924700.0 1453.8 1149.9 6296.2 9156.0 5708.0 5755.9 1432.3 7891.5 1890.0 4396.1 True False 1916.0781590814777 1521.5826874799072 6212.7082741360055 7045.225658789864 4915.5427272519255 5395.982663090191 1559.7719252672387 6672.0500036296535 1989.9015414885275 4242.193877068699 0.4516715205872351 0.3586782527090207 1.4645036163290364 1.6607505132834766 1.1587265621741223 1.2719792681466846 0.36768049044119144 1.572782903604574 0.46907369138525173 1.0 12.050594841196254 -5.247373625851093 24.543430106471508 1.14030038655377 0.40517470508638037 0.3306213762684683 0.4064715292650212 696.4108216512733 1215165.2988129917 0.10260202285260021 0.2684000945646632 5.657523598521998e-06 5.247373625851093 -0.7351256814673897 GHLSRPEAQSLSPYTT(ph)SANR ddPTM_PC-9_Lapatinib_30min_R1 1 GHLSRPEAQSLSPYTTSANR 20 1 O94776;O94776-2 O94776 MTA2 Metastasis-associated protein MTA2 1 GHLSRPEAQS(0.001)LS(0.012)PY(0.007)T(0.155)T(0.413)S(0.413)ANR 62.765 0.006790600000000001 3238300.0 5460.3 6527.0 11629.0 6004.7 9249.5 8080.5 4717.4 7762.7 10969.0 5920.5 True False 5382.435120703615 6511.887132517684 10672.908509238141 6446.305669091991 8705.462595216672 7734.915851565513 4961.643889584528 8123.383381129613 9733.555711309267 6943.850536429636 0.7751369492280483 0.9377919496328824 1.5370302763927144 0.9283474111766422 1.2536938330606429 1.1139231484009768 0.7145378293432691 1.1698672571524653 1.4017519041119846 1.0 12.761520179352253 -5.008437905861262 24.391311749636188 1.1337548871035756 0.8158004030326251 0.22268311462469326 0.22091067236210976 427.39184010932405 1235494.0033911667 0.05547069032874242 0.18069506283336062 9.807585302477673e-06 5.008437905861262 -0.3179544840709505 GHLSRPEAQSLSPYTTS(ph)ANR ddPTM_PC-9_AZD4547_30min_R2 1 GHLSRPEAQSLSPYTTSANR 20 1 O94776;O94776-2 O94776 MTA2 Metastasis-associated protein MTA2 1 GHLSRPEAQS(0.001)LS(0.146)PY(0.009)T(0.296)T(0.12)S(0.428)ANR 65.064 0.0031164 5573500.0 1141.9 1234.0 4200.3 9530.4 3607.6 3967.6 2538.4 4870.7 2874.5 4015.7 True False 1505.0004470044976 1632.8663678147705 4144.601277572737 7333.313523212197 3106.747011708839 3719.5053447899772 2764.312682467612 4118.045232551348 3026.440201591943 3875.111565283953 0.38837603037997104 0.4213727373537232 1.0695437299671748 1.8924135214349216 0.8017180820137727 0.9598447121140953 0.7133504767275143 1.062690754362731 0.7809943405771796 1.0 11.920022131143133 -5.258750709361689 20.48848086407522 1.0454174073937281 0.40487330334577626 0.3960246130421855 0.3110932438506938 19.175462078998493 146086.76864169518 0.08472539002460124 0.20288736214606645 5.511239578931481e-06 5.258750709361689 -0.6405441040479518 GHPHSAS(ph)SPSER ddPTM_PC-9_AZD4547_30min_R2 5 GHPHSASSPSER 12 0 C9J470;E9PHA2;Q15003;C9JZP1 C9J470 NCAPH Condensin complex subunit 2 1 GHPHS(0.002)AS(0.465)S(0.32)PS(0.213)ER;GHPHSAS(0.493)S(0.493)PS(0.014)ER;GHPHSAS(0.667)S(0.201)PS(0.132)ER;GHPHSAS(0.619)S(0.3)PS(0.08)ER;GHPHS(0.02)AS(0.327)S(0.327)PS(0.327)ER 148.85 8.2217e-05 148904130.0 130283.4 97439.1 275909.5 357710.6 270213.30000000005 306835.9 183831.4 278870.89999999997 330611.1 425569.5 True False 171710.81113693488 128934.38354954642 272250.7597539353 275245.9477436782 232698.84751607318 287649.402667468 200192.03847139011 235777.81022076998 348086.52779006236 410670.44133827416 0.41812313196287393 0.3139607105137173 0.6629421851417815 0.6702355953516381 0.5666315957821673 0.7004385358977607 0.48747613248962696 0.5741290009878188 0.8476055073643328 1.0 18.64762158520803 -14.522878745280334 0.06666699100430123 2.546485432303028 1.5679161110391613e-13 0.6444497914158118 0.11373160612994199 236.47622491783113 1.136532885575566 56.6523155766987 7.735328215118326 3.000000000000026e-15 14.522878745280334 -2.5464854323028714 GHPHSAS(ph)SPSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 GHPHSASSPSER 12 0 C9J470;E9PHA2;Q15003;C9JZP1 C9J470 NCAPH Condensin complex subunit 2 1 GHPHSAS(0.591)S(0.247)PS(0.162)ER;GHPHS(0.002)AS(0.381)S(0.381)PS(0.236)ER;GHPHSAS(0.538)S(0.269)PS(0.192)ER;GHPHS(0.002)AS(0.436)S(0.436)PS(0.126)ER;GHPHSAS(0.715)S(0.169)PS(0.116)ER;GHPHSAS(0.373)S(0.373)PS(0.254)ER 147.7 4.8626000000000005e-05 87331600.0 32886.5 53995.7 123700.6 79543.0 212114.8 199703.3 83922.07 140360.75 203864.3 170156.09999999998 True False 38453.53491201745 59356.03625085042 126650.09144113821 75086.46359188549 170552.4276188324 189230.5073904325 75972.36398642905 136676.42903700753 206845.4297141364 201004.05397505313 0.19130726048336302 0.2952977070712075 0.6300872491698944 0.3735569612004172 0.8485024269211996 0.9414263227443072 0.3779643369573933 0.6799685197094115 1.0290609847093346 1.0 17.61686507330731 -5.304051960779398 0.5056172038776504 0.8329794817321127 8.988864893104473e-44 0.5516222026245751 0.1982642076368387 2.4866602838199827 0.7130777883556796 0.14202594439366406 1.1581199019366781 4.9653291065514016e-06 5.304051960779398 -0.8329794817321127 GHPHSAS(ph)SPSER ddPTM_PC-9_Lapatinib_30min_R1 5 GHPHSASSPSER 12 0 C9J470;E9PHA2;Q15003;C9JZP1 C9J470 NCAPH Condensin complex subunit 2 1 GHPHS(0.001)AS(0.482)S(0.482)PS(0.035)ER;GHPHSAS(0.465)S(0.218)PS(0.317)ER;GHPHSAS(0.394)S(0.394)PS(0.212)ER;GHPHS(0.002)AS(0.44)S(0.44)PS(0.118)ER;GHPHSAS(0.47)S(0.47)PS(0.06)ER 149.32 3.5034000000000004e-05 103732860.0 90586.89 72950.12000000001 127089.43 79053.12 167281.82 124073.34999999999 148703.76 194936.13999999998 222415.49999999997 135338.97000000003 True False 89295.10433699895 72781.2084791822 116640.6276447867 84866.95015827773 157442.63223631185 118767.02204960544 156402.9130797142 203993.58471376626 197364.7242509535 158732.13063665788 0.5625521687313443 0.4585159172705893 0.7348268254004618 0.5346551439704446 0.9918762609991185 0.7482229437306953 0.98532611168513 1.2851436183434914 1.2433823162288842 1.0 17.276234663216577 -6.792480203937279 0.7609590703755863 1.1965034488426058 0.5328225542559456 0.7461432541782733 0.13924605186373368 0.32052124617486144 0.4050263023648441 0.09809560166886822 0.09301861723563151 1.6125745302265268e-07 6.792480203937279 -0.6636808945866602 GHPHSASS(ph)PSER ddPTM_PC-9_AZD4547_30min_R2 2 GHPHSASSPSER 12 0 C9J470;E9PHA2;Q15003;C9JZP1 C9J470 NCAPH Condensin complex subunit 2 1 GHPHS(0.001)AS(0.139)S(0.525)PS(0.335)ER;GHPHSAS(0.097)S(0.451)PS(0.451)ER 155.09 0.00017057 58234050.0 15789.5 12733.55 30915.1 44290.4 35990.6 37851.3 22862.2 33855.4 42836.9 60482.6 True False 20810.232557997664 16849.421019358007 30505.145574432496 34079.932559858746 30993.926432977092 35484.45222735379 24896.891510050038 28623.82584969692 45101.17108073542 58365.122583470635 0.35655253748908 0.2886898934421131 0.5226605243706237 0.583909208982119 0.5310350610272643 0.6079735749137826 0.42657139072129685 0.49042689508208737 0.772741820532188 1.0 15.832818890657267 -14.522878745280336 0.10400652247265114 2.6319970532747616 0.1843797338095307 0.7566103402274178 0.09636934203792791 96.28534128106763 0.6727260551264669 33.53619794653666 1.5701818705131947 3.0000000000000132e-15 14.522878745280336 -2.447617319465231 GHPHSASS(ph)PSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GHPHSASSPSER 12 0 C9J470;E9PHA2;Q15003;C9JZP1 C9J470 NCAPH Condensin complex subunit 2 1 GHPHSAS(0.139)S(0.521)PS(0.339)ER;GHPHS(0.001)AS(0.302)S(0.601)PS(0.096)ER 145.49 6.2773e-05 44141360.0 3439.4799999999996 6335.13 12197.57 10902.77 25615.4 22296.3 12396.17 15088.8 23810.4 19221.0 True False 4021.7160311734538 6964.0398389844 12488.406328341822 10291.92314415726 20596.246251687484 21127.04277760709 11221.915037101111 14692.7349879051 24158.58205514875 22705.615146647724 0.177124293052559 0.30671002718957724 0.5500140052442323 0.4532765607839859 0.907099240371311 0.9304765645482327 0.4942352349682067 0.6470969798884462 1.0639915236436808 1.0 14.470761502724214 -5.303361530109818 0.6911566771855032 0.8278487812354439 2.307188686649296e-11 0.6446505289050855 0.17410080262471736 1.2383640773241602 0.7109274823750046 0.0879055359467376 0.7233834594116697 4.973229142433982e-06 5.303361530109818 -0.827848781212372 GHPHSASS(ph)PSER ddPTM_PC-9_Lapatinib_30min_R1 3 GHPHSASSPSER 12 0 C9J470;E9PHA2;Q15003;C9JZP1 C9J470 NCAPH Condensin complex subunit 2 1 GHPHSAS(0.155)S(0.528)PS(0.317)ER;GHPHS(0.001)AS(0.278)S(0.671)PS(0.05)ER;GHPHS(0.001)AS(0.177)S(0.605)PS(0.217)ER 168.0 7.6661e-05 95380660.0 73687.0 64719.9 103909.7 68567.0 131425.7 100162.79999999999 103609.29999999999 149006.3 183885.9 86148.4 True False 72636.20986745901 64570.04504792877 95366.64556904143 73609.64591280665 123695.49871886776 95879.0705348909 108973.68258980155 155929.676672242 163174.7335376282 101039.03615447234 0.718892545217969 0.6390603820607672 0.9438594151199271 0.7285268022575889 1.2242347455666278 0.9489309694948723 1.0785305040241915 1.543261719498697 1.6149672418505698 1.0 16.62455325638478 -6.711875368449792 0.7470718482545913 1.3912767930875478 0.7078142939370614 0.5633136583236944 0.20888046637131105 0.4877678451064849 0.6009926696712774 0.14697188567863897 0.15299613189230152 1.9414429427595495e-07 6.711875368449792 -0.6834624991504864 GHPHSASSPS(ph)ER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GHPHSASSPSER 12 0 C9J470;E9PHA2;Q15003;C9JZP1 C9J470 NCAPH Condensin complex subunit 2 1 GHPHS(0.005)AS(0.288)S(0.288)PS(0.419)ER 128.95 0.0001075 522440.0 1093.5 1099.2 2691.0 1121.5 4038.4 3483.1 544.97 2268.1 2888.9 2870.4 True False 1278.607952390527 1208.321311640275 2755.16364567433 1058.665990952057 3247.104509896963 3300.4401043528865 493.34649635887433 2208.5647782505944 2931.1446972381505 3390.780797926103 0.37708363606770445 0.35635488804800314 0.8125454902184965 0.3122189413127404 0.9576273735780808 0.9733569643816341 0.14549642862806672 0.6513440148066826 0.8644453510621863 1.0 11.727401806870697 -10.325933384220125 0.07380030937414678 1.759171283888349 1.0581974514754437e-14 0.23229001840161068 0.2662220314442892 154.45068841224497 2.4066543649079937 40.81520874186318 18.472865506392885 4.721354558598383e-11 10.325933384220125 -1.7591712838883384 GHPHSASSPS(ph)ER ddPTM_PC-9_Lapatinib_30min_R1 2 GHPHSASSPSER 12 0 C9J470;E9PHA2;Q15003;C9JZP1 C9J470 NCAPH Condensin complex subunit 2 1 GHPHS(0.053)AS(0.031)S(0.031)PS(0.886)ER;GHPHSAS(0.028)S(0.15)PS(0.823)ER 158.31 0.00020294 1601520.0 3285.6 5189.799999999999 7037.5 4696.3 7813.2 5498.299999999999 8601.1 10928.5 14088.2 6757.3 True False 3238.746741494752 5177.78333696036 6458.903915535597 5041.6815683975465 7353.6429373422225 5263.150526163311 9046.422872494482 11436.278006450719 12501.43856067712 7925.290301463724 0.4086596980424284 0.6533241231559775 0.8149737952618216 0.636151027485567 0.9278704826729283 0.6640956136573645 1.1414626503742955 1.4430106117801829 1.5774108058058423 1.0 12.95224806645185 -7.414467018779831 2.8638576558430606 1.3797363322112417 0.6942934555611704 0.7203482353683052 0.18700097639755034 0.13978231256917 2.211083009461456 0.0900628503762661 0.05475248744524845 3.850640561282027e-08 7.414467018779831 -0.6854428766500713 GHQFSCVCLHGDR ddPTM_PC-9_AZD4547_30min_R2 3 GHQFSCVCLHGDR 13 0 F1T0B3;A0A087X2G1;Q92499-3;Q92499-2;Q92499 F1T0B3 DDX1 ATP-dependent RNA helicase DDX1 0 ;; 134.18 1.9122e-05 9671600.0 12742.2 10812.400000000001 22136.300000000003 29583.4 20395.3 17482.100000000002 11712.2 25426.2 15411.6 18154.7 False True 16793.95454577521 14307.296851993871 21842.75819839852 22763.404188973782 17563.76464350407 16388.941523377576 12754.563110462173 21497.165025950475 16226.225712595013 17519.109478860617 0.9586077743300587 0.8166680429309338 1.246796147073287 1.2993471053104142 1.0025489403269805 0.9354894176072845 0.7280371828175645 1.227069506694388 0.9262015133916676 1.0 14.096641822120734 -6.509968736051675 24.379241424585725 0.9635298554580076 1.0831010803301753 0.09572114074802884 0.16984206022880896 1201.425993363331 2268776.437731714 0.05767615785287921 0.06240261127502054 3.090517904403907e-07 6.509968736051675 0.11957122487216765 GHQFSCVCLHGDR ddPTM_PC-9_Lapatinib_30min_R1 1 GHQFSCVCLHGDR 13 0 F1T0B3;A0A087X2G1;Q92499-3;Q92499-2;Q92499 F1T0B3 DDX1 ATP-dependent RNA helicase DDX1 0 68.277 0.013962 2416300.0 6796.7 7270.5 5963.9 7670.3 6866.9 5610.8 7379.9 5836.4 8338.8 4686.0 False True 6699.777811637872 7253.665603948185 5473.571163319744 8234.399449370712 6463.0024428448405 5370.839163413623 7761.9951118719755 6107.580450825725 7399.596532543144 5495.968856297486 1.2190348939042872 1.3198156309850018 0.9959247052588229 1.4982616649902283 1.1759532507974988 0.9772324596161995 1.412306968038582 1.1112836718183785 1.3463679882509543 1.0 12.424158113601129 GHQQLYWSHPR ddPTM_PC-9_AZD4547_30min_R2 2 GHQQLYWSHPR 11 0 A0A2R8Y851;P62273;P62273-2 A0A2R8Y851 RPS29 40S ribosomal protein S29 0 ; 119.34 0.00041017 39597000.0 38465.0 48783.0 68120.0 91141.0 83299.0 90305.0 53150.0 81882.0 66759.0 69879.0 False True 50696.06987829758 64551.1507464408 67216.68429118276 70129.85056441325 71734.37169540266 84658.21407431675 57880.24703480677 69229.01836117383 70287.74444880038 67432.55747951228 0.7518040509393453 0.957269799029246 0.9967986800975907 1.0399998633556273 1.0637943209731795 1.2554501451326099 0.8583427530891478 1.0266408534513518 1.0423413715274787 1.0 16.041157694597032 -4.398778208507007 1.2654249999522416 1.042869884179476 0.3334262382927777 0.47260425804326833 0.09097351126821988 2.952540776026329 2.1598331499978505 0.02728523788133348 3.4448244823517937 3.9922873394337615e-05 4.398778208507007 -0.7094436458866982 GHQQLYWSHPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GHQQLYWSHPR 11 0 A0A2R8Y851;P62273;P62273-2 A0A2R8Y851 RPS29 40S ribosomal protein S29 0 ; 141.91 5.7112e-05 28933000.0 40426.0 46731.0 56262.0 61889.0 64055.0 54837.0 64900.0 62683.0 58948.0 43625.0 False True 47269.3233501047 51370.144845580144 57603.49945482323 58421.559976845194 51503.882572664945 51961.25118497865 58752.20216468968 61037.637668128424 59810.00298134049 51533.86716469003 0.9172477431015053 0.996823015074986 1.1177794841348911 1.1336537153352713 0.9994181575403751 1.0082932650663068 1.1400697327241436 1.1844179570895892 1.1605960559917208 1.0 15.653233237710538 -7.269838398998868 23.949073605084468 1.1366391138699694 1.0348782047633576 0.2586047652895832 0.07444279182356471 484.2864748864312 1380891.9797983267 0.032146400828615126 0.022100460142112737 5.372316631147814e-08 7.269838398998868 -0.10176090910661184 GHQQLYWSHPR ddPTM_PC-9_Lapatinib_30min_R1 2 GHQQLYWSHPR 11 0 A0A2R8Y851;P62273;P62273-2 A0A2R8Y851 RPS29 40S ribosomal protein S29 0 ; 157.75 0.00037914 27605000.0 70699.0 56497.0 68030.0 52289.0 63535.0 71475.0 58191.0 53217.0 70135.0 56015.0 False True 69690.81929539138 56366.18466766535 62436.83600339419 56134.50749099061 59797.996214616054 68418.18086636283 61203.845249250284 55689.656098209955 62235.65774570839 65697.11811470418 1.0607895946624992 0.8579704298330493 0.9503740467638523 0.8544439863097544 0.9102072957022479 1.0414182970234371 0.931606240967696 0.8476727396318716 0.9473118385048148 1.0 16.003542465883747 -4.743249849939623 24.947647291152766 0.9237105430645651 1.0607900396172918 0.3082067000292694 0.060074298084465495 1471.4735775139134 2018074.2716138503 0.014983222096095867 0.48750123826749897 1.8061347563909723e-05 4.743249849939623 0.13707949655272667 GHSGTT(ph)ASGGENER ddPTM_PC-9_Lapatinib_30min_R1 1 GHSGTTASGGENER 14 0 Q9BRS8 Q9BRS8 LARP6 La-related protein 6 1 GHS(0.006)GT(0.103)T(0.497)AS(0.395)GGENER 76.759 0.045488 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GHTAS(ph)ESDEQQWPEEK ddPTM_PC-9_AZD4547_30min_R2 3 GHTASESDEQQWPEEK 16 0 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 GHT(0.176)AS(0.699)ES(0.124)DEQQWPEEK;GHT(0.003)AS(0.676)ES(0.32)DEQQWPEEK;GHT(0.41)AS(0.556)ES(0.034)DEQQWPEEK 165.89 2.1673e-05 82621000.0 266283.0 298361.0 398188.0 418719.0 365442.0 393738.0 374139.0 460295.0 358239.0 341980.0 True False 350955.4549695242 394800.358482644 392907.7669485824 322189.80369406176 314706.68628808635 369117.50061672507 407436.64619671926 389166.98427684326 377174.78218058636 330007.3842906109 1.0634775816424338 1.1963379526531297 1.1906029551223016 0.9763108919112403 0.9536352859636302 1.1185128520993126 1.2346288767827167 1.179267503705721 1.1429283105024066 1.0 18.332138781211704 -6.999623077622395 24.99999740446791 1.157348815254262 1.0788247018592296 0.08373160799795909 0.09172784998489888 29.030286402951166 1925323.8608876318 0.034837442718385 0.030435255438671295 1.0008682725784695e-07 6.999623077622395 -0.07852411339503229 GHTAS(ph)ESDEQQWPEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GHTASESDEQQWPEEK 16 0 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 GHT(0.043)AS(0.9)ES(0.057)DEQQWPEEK;GHT(0.177)AS(0.645)ES(0.177)DEQQWPEEK 109.77 0.00036599 30334000.0 66075.0 83707.0 92700.0 96478.0 110728.0 96168.0 130628.0 122689.0 112778.0 89755.0 True False 77260.1924592632 92016.87775970918 94910.31956670787 91072.65044589624 89031.64326759896 91124.78078591143 118253.97017517837 119468.54374974099 114427.16489498588 106026.87099981074 0.7286850185308318 0.867863748991267 0.8951534518723776 0.8589582017001974 0.8397082968501248 0.8594498727221148 1.1153207584083988 1.1267760957498618 1.0792279713242705 1.0 16.694070416067994 -7.2493996668049885 11.358933181294 1.090912376714877 0.8459219765232838 0.8328844762203244 0.05227293413881104 0.22404331432559135 209.66328465496431 0.020211935225028493 0.015193182326714983 5.6311919738530514e-08 7.2493996668049885 -0.24499040019159313 GHTAS(ph)ESDEQQWPEEK ddPTM_PC-9_Lapatinib_30min_R1 3 GHTASESDEQQWPEEK 16 0 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 GHT(0.134)AS(0.732)ES(0.134)DEQQWPEEK;GHT(0.03)AS(0.79)ES(0.18)DEQQWPEEK;GHT(0.055)AS(0.895)ES(0.05)DEQQWPEEK 136.33 5.7037e-06 46050000.0 129083.0 158580.0 200083.0 164471.0 203519.0 276924.0 266603.0 281036.0 272896.0 219950.0 True False 127242.25274907697 158212.81775312597 183632.94808271536 176566.7459991721 191548.41255374896 265080.6060613736 280406.39884150255 294093.9585323589 242159.5787577223 257968.0644350469 0.4932480810279327 0.6133038913154383 0.7118437256366352 0.6844519548799785 0.7425276185765174 1.0275714036227828 1.086981055021659 1.1400401796882422 0.9387192142874532 1.0 17.97683295042284 -6.648927636796494 2.126828300602364 1.059362627027262 0.6274273976941577 0.8761584962871491 0.07408134019470602 0.10568172123796872 0.977874686645037 0.029229193837424398 0.028990268185449856 2.244255836e-07 6.648927636796494 -0.43193522933310435 GHTAS(ph)ESDEQQWPEEKR ddPTM_PC-9_Lapatinib_30min_R1 2 GHTASESDEQQWPEEKR 17 1 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 GHT(0.012)AS(0.823)ES(0.164)DEQQWPEEKR;GHT(0.059)AS(0.47)ES(0.47)DEQQWPEEKR 85.146 0.0015058 15247900.0 22260.5 18001.0 20286.2 18764.4 19569.6 26921.0 22454.2 21685.0 29149.0 17177.3 True False 21943.06118792425 17959.319790478145 18618.346942996537 20144.396572203415 18418.55460331392 25769.651585916097 23616.768606755613 22692.56426498457 25865.93266742219 20146.37341768646 1.0891816970224766 0.8914418202291284 0.9241537698617027 0.9999018758641042 0.9142367324108224 1.2791211128496691 1.1722590521439704 1.1263845752537682 1.2839001904290397 1.0 14.29823253973167 -6.752833999930716 24.999408341878905 1.1802274063119356 0.9595691505734889 0.5681314562576605 0.09074650981925844 126.89223899207474 368633.0032019393 0.028527894020621797 0.0281017350849662 1.7667129810844126e-07 6.752833999930716 -0.22065825573844666 GHTASES(ph)DEQQWPEEK ddPTM_PC-9_AZD4547_30min_R2 2 GHTASESDEQQWPEEK 16 0 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 GHT(0.071)AS(0.398)ES(0.531)DEQQWPEEK;GHT(0.009)AS(0.216)ES(0.776)DEQQWPEEK 108.14 0.00046943 17863400.0 138395.0 160822.0 200724.0 214462.0 184523.0 195985.0 190283.0 222486.0 192632.0 174707.0 True False 182401.73120517333 212804.5664543815 198062.26860926836 165021.09930487027 158905.16654882763 183730.02696810797 207217.8183729848 188105.90091966637 202814.13425397762 168590.56110667184 1.0819213721565515 1.262256706766248 1.174812322286234 0.9788276296230898 0.9425507899477481 1.089800198552379 1.229118741955384 1.1157558269270285 1.2029981567334105 1.0 17.36316424069433 -9.023720691534153 0.006970578347412443 2.6701512748675262e-05 2.184571480501639 0.03866491065290989 0.1022461471532729 26613.16943678557 78.15128915921352 12455.72604227445 12030.561270262253 9.468459120324012e-10 9.023720691534153 2.18454477898889 GHTASES(ph)DEQQWPEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GHTASESDEQQWPEEK 16 0 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 GHT(0.082)AS(0.403)ES(0.515)DEQQWPEEK;GHT(0.044)AS(0.162)ES(0.794)DEQQWPEEK 89.669 0.0020962 12568000.0 54816.0 68853.0 71949.0 68663.0 92735.0 81508.0 92749.0 83034.0 78358.0 71882.0 True False 64095.26613464948 75688.27080637532 73664.53702810206 64816.03471844947 74564.24245376741 77233.5769933665 83963.14327539006 80854.44548179541 79503.83751122832 84913.63758240096 0.7548288821386419 0.8913558877150534 0.8675230401785264 0.7633171368444958 0.8781185752572382 0.9095544507608491 0.9888063409592066 0.9521962288252406 0.9362905626799592 1.0 16.373708656442844 -6.805393928816611 2.175357449822026 0.9643800030453077 0.8279402414639283 0.6947534154292659 0.043869312088530364 0.186641266454764 1.8135143940547047 0.017408680078583046 0.015580982865386131 1.565330585636213e-07 6.805393928816611 -0.13643976158137938 GHTASES(ph)DEQQWPEEK ddPTM_PC-9_Lapatinib_30min_R1 1 GHTASESDEQQWPEEK 16 0 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 GHT(0.124)AS(0.15)ES(0.726)DEQQWPEEK 72.77199999999999 0.0088917 23910000.0 19100.0 24348.0 30802.0 23162.0 30122.0 32421.0 34088.0 35212.0 33365.0 25228.0 True False 18827.630497488975 24291.623701936664 28269.57845915843 24865.41074616695 28350.28318213056 31034.429407042324 35852.90984613504 36848.078067725895 29607.082350973986 29588.626185803038 0.6363131015025865 0.8209784242565498 0.955420447087959 0.8403705731392712 0.9581480060650247 1.0488634792355787 1.2117125553918984 1.2453460270962504 1.000623758773221 1.0 14.852755092609137 -5.4889756963339895 0.5581632278748492 1.1333687281902927 0.5798886594083427 0.6796715461709188 0.0968756682374998 1.2140118270800417 0.49543254922655705 0.06502918991308004 0.3976262465212668 3.2435776831057e-06 5.4889756963339895 -0.55348006878195 GHTASES(ph)DEQQWPEEKR ddPTM_PC-9_AZD4547_30min_R2 1 GHTASESDEQQWPEEKR 17 1 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 GHT(0.005)AS(0.312)ES(0.683)DEQQWPEEKR 90.755 0.0010689999999999999 8928600.0 20015.0 15625.0 24970.0 42645.0 37581.0 28059.0 24883.0 30462.0 21519.0 28435.0 True False 26379.353662137695 20675.47568647147 24638.881484891826 32813.854108682164 32363.526845279393 26304.46629434972 27097.538795241722 25754.797847122394 22656.450408090797 27439.499304940397 0.9613642497255106 0.7534931835563382 0.8979348059917286 1.195861985090017 1.1794503422098683 0.9586350684472469 0.98753765490039 0.9386030539735586 0.8256874572055902 1.0 14.74396653610136 -5.538456541630808 24.8344178896904 1.0159750045868814 0.8494999780727115 0.25158095908344136 0.11285475309752308 281.8731221363495 449365.6722989815 0.033072665259022895 0.05730650474501609 2.894299425257549e-06 5.538456541630808 -0.1664750265141699 GHTDT(ph)EGRPPSPPPTS(ph)TPEK ddPTM_PC-9_Lapatinib_30min_R1 2 GHTDTEGRPPSPPPTSTPEK 20 1 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 2 GHT(0.096)DT(0.49)EGRPPS(0.412)PPPT(0.034)S(0.517)T(0.451)PEK;GHT(0.132)DT(0.711)EGRPPS(0.157)PPPT(0.109)S(0.486)T(0.406)PEK 74.63 0.0090427 10055000.0 70098.0 53580.0 56497.0 59739.0 61741.0 51828.0 49548.0 46287.0 54945.0 43886.0 True False 69098.38966560115 53455.93880194536 51852.034744726756 64132.40534346204 58109.515767476325 49611.43725696889 52113.35299977403 48437.66299900117 48756.51550349966 51471.63662558075 1.3424556551065665 1.0385513713270667 1.0073904414952477 1.2459756391656884 1.128961882253354 0.9638597198269898 1.0124673784682874 0.9410554273094216 0.9472501497896472 1.0 15.651490035691534 -6.7395378708268305 6.285984084019683 0.9713637871353912 1.1443659021680603 0.4901819349671661 0.09150439119733741 0.15723647744927033 21.163774551206664 0.03133205842906679 0.030311404583943387 1.8216382178535077e-07 6.7395378708268305 0.17300211503266916 GHTDTEGRPPS(ph)PPPT(ph)STPEK ddPTM_PC-9_Lapatinib_30min_R1 1 GHTDTEGRPPSPPPTSTPEK 20 1 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 2 GHT(0.006)DT(0.091)EGRPPS(0.903)PPPT(0.416)S(0.311)T(0.273)PEK 66.613 0.021574 4861900.0 34969.0 21951.0 28091.0 30117.0 26256.0 28003.0 29291.0 24808.0 26994.0 26300.0 True False 34470.335647470776 21900.17380816543 25781.466414395803 32331.90464736684 24711.67370128212 26805.376968181296 30807.544658036273 25960.670246056565 23953.65146057821 30845.91995745282 1.1175006514643517 0.7099860804402441 0.8358144756245672 1.0481744325331748 0.8011326533741919 0.8690088350470717 0.9987559035532259 0.8416241202034271 0.7765581799349337 1.0 14.91279205380502 -4.731909168508092 24.866793451342076 0.8761773408581882 1.1175021879096636 0.33180021477209787 0.10295157239421746 4219.4729789378825 3552925.2739988356 0.02533542059934205 2.9878669243748384 1.8539193249786392e-05 4.731909168508092 0.2413248470514754 GHTDTEGRPPS(ph)PPPTST(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 2 GHTDTEGRPPSPPPTSTPEK 20 1 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 2 GHTDT(0.002)EGRPPS(0.992)PPPT(0.267)S(0.177)T(0.561)PEK;GHT(0.028)DT(0.358)EGRPPS(0.614)PPPT(0.26)S(0.228)T(0.512)PEK 75.529 0.009379700000000001 8761100.0 48479.0 37836.0 44275.0 43021.0 42690.0 40254.0 40094.0 37405.0 42396.0 36248.0 True False 47787.68057004025 37748.39306663693 40634.88040644242 46184.90785384892 40179.05813176923 38532.430256657164 42169.871138551294 39142.972853666 37620.916030328 42513.41850257604 1.1240611141902086 0.8879171423100125 0.955813054741298 1.0863607181118689 0.945091209951386 0.906359253474814 0.9919190839945292 0.9207204273938636 0.8849186293510699 1.0 15.375630650251383 -6.487468232831398 24.856985093100565 0.9375467586519608 1.002352398714458 0.19884334601361975 0.06929214285281476 1028.0663050978274 721668.0873616881 0.02124911445786915 0.02408393806916912 3.25485590794526e-07 6.487468232831398 0.06480564006249723 GHTDTEGRPPS(ph)PPPTSTPEK ddPTM_PC-9_AZD4547_30min_R2 2 GHTDTEGRPPSPPPTSTPEK 20 1 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 1 GHT(0.148)DT(0.031)EGRPPS(0.818)PPPT(0.002)S(0.001)T(0.001)PEK;GHT(0.001)DT(0.001)EGRPPS(0.995)PPPT(0.001)S(0.001)T(0.001)PEK 59.07 0.0067684 94353000.0 98508.0 93319.0 113300.0 147525.0 133256.0 117638.0 98078.0 127947.0 102615.0 120376.0 True False 129831.49490631344 123482.54179749313 111797.5679710951 113515.39048852939 114755.70456599203 110282.07726343464 106806.75199773819 108175.73107956674 108039.01940732545 116161.67287960285 1.1176792799883215 1.0630231016514207 0.9624307673923482 0.9772189714087862 0.9878964526012978 0.9493843754965359 0.9194663725998448 0.9312514911152043 0.9300745825114259 1.0 16.825774609723062 -4.219574100045196 0.70759564265544 0.9443580161902958 1.4178993795208192 0.8137056958454361 0.025879152572400345 2.370991258953242 0.5109121313057181 0.010689102661633424 1.0770642896394926 6.0315078855827854e-05 4.219574100045196 0.47354136333052343 GHTDTEGRPPS(ph)PPPTSTPEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GHTDTEGRPPSPPPTSTPEK 20 1 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 1 GHT(0.002)DT(0.002)EGRPPS(0.905)PPPT(0.038)S(0.026)T(0.026)PEK;GHT(0.012)DT(0.003)EGRPPS(0.985)PPPTSTPEK;GHT(0.001)DT(0.003)EGRPPS(0.988)PPPT(0.002)S(0.002)T(0.002)PEK 61.736000000000004 0.004749300000000001 71676000.0 73281.9 85678.6 80545.0 94535.0 100059.0 93546.0 78455.0 75614.0 89142.0 78563.1 True False 85687.07828649989 94184.20517785894 82465.49826861345 89238.51043660505 80453.1572295416 88640.28308167872 71023.17443498828 73629.21261965559 90445.53310990457 92805.96812484275 0.923292758190222 1.0148507373056244 0.8885796887295083 0.9615600401534656 0.8668963737473852 0.9551140392441104 0.765286714529477 0.7933672166493586 0.9745659135653548 1.0 16.501929964075337 -6.201693422976427 1.241224855346793 0.8745974267603057 0.9565158879648248 0.06962394509018666 0.07764881824421536 0.8986791561581126 2.8251773757714345 0.030625294158119237 0.0469700033184379 6.285018740963813e-07 6.201693422976427 0.08191846120451907 GHTDTEGRPPS(ph)PPPTSTPEK ddPTM_PC-9_Lapatinib_30min_R1 3 GHTDTEGRPPSPPPTSTPEK 20 1 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 1 GHT(0.018)DT(0.162)EGRPPS(0.82)PPPTSTPEK;GHT(0.002)DT(0.006)EGRPPS(0.991)PPPTSTPEK;GHT(0.058)DT(0.058)EGRPPS(0.881)PPPT(0.001)S(0.001)TPEK 61.16 0.005806 90772000.0 51007.0 74177.0 50494.4 53362.0 52711.1 40596.8 47049.6 51468.0 58350.1 45127.0 True False 50279.630826461806 74005.24771392137 46342.94534602065 57286.41949041368 49610.73673200986 38860.56949976296 49485.59807253915 53859.39117317154 51778.09728420705 52927.141822052174 0.9499781982467211 1.398247575180547 0.8755988657356856 1.0823637460533568 0.9373401816936857 0.7342276223873409 0.9349758246707534 1.0176138238156467 0.9782900701173632 1.0 15.691720127032768 -5.290189693914376 24.99069506491924 0.9424196911313593 1.1741130435775056 0.32009023857148367 0.13349292688301456 688.0094004307359 598038.6337238791 0.03407339910793719 0.07094740611206968 5.1263742203960445e-06 5.290189693914376 0.2316933524461463 GHTESCSCPLQQS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 GHTESCSCPLQQSPR 15 0 C9JGT3;G5E9C5;O76074-2;O76074 C9JGT3 PDE5A cGMP-specific 3,5-cyclic phosphodiesterase 1 GHTESCS(0.001)CPLQQS(0.999)PR;GHTESCSCPLQQS(1)PR 103.99 0.00067884 5538600.0 14771.3 14744.9 33278.0 48915.0 39212.0 37212.0 28458.0 43754.0 27356.0 30235.0 True False 19468.266137873325 19510.900572765007 32836.71197654107 37638.4024792165 33768.09064838868 34885.12775741622 30990.706869549023 36992.82466689624 28801.982311619136 29176.481852817764 0.6672588640426894 0.6687201243518232 1.1254513872572958 1.2900253933659762 1.1573736277983588 1.1956591590924504 1.062181075356625 1.2678987430187234 0.987164335196827 1.0 14.83251831080068 -5.269261556451698 5.8568854218678865 1.152306413781255 0.6639063614233381 0.7892213394271604 0.0964538556176841 0.055785722651825395 8.2013538237375 0.023707650090731724 0.05568680753472918 5.379457039162655e-06 5.269261556451698 -0.48840005235791695 GHTESCSCPLQQS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 GHTESCSCPLQQSPR 15 0 C9JGT3;G5E9C5;O76074-2;O76074 C9JGT3 PDE5A cGMP-specific 3,5-cyclic phosphodiesterase 1 GHTESCSCPLQQS(0.999)PR;GHTESCSCPLQQS(1)PR 75.564 0.008411499999999999 4273900.0 9437.5 10595.0 15083.8 8531.8 11489.7 13093.900000000001 12526.9 10296.5 14309.7 10422.7 True False 9302.91951937446 10570.467928454857 13843.668189151802 9159.257033250467 10813.898435619321 12533.90442037172 13175.481587407558 10774.912979221286 12697.990898178705 12224.249807625221 0.7610217122339483 0.8647130167334464 1.1324758907099906 0.7492694584445683 0.8846267546720001 1.0253311751330003 1.077815145694174 0.8814375645775931 1.0387542056166075 1.0 13.577458310409737 -6.754087171243999 24.03858521518029 1.0018291906313253 0.8845987875057165 0.2519583481974479 0.10844859863859384 171.58753017848045 561016.5265251729 0.03679354293269034 0.036048796114199845 1.761622419467942e-07 6.754087171243999 -0.11723040312560873 GHVS(ph)PAEDQTIQAPPVSVSALAR ddPTM_PC-9_Lapatinib_30min_R1 1 GHVSPAEDQTIQAPPVSVSALAR 23 0 E9PEM3;H7C357;H0Y6E6;Q92622-3;Q92622-2;Q92622 E9PEM3 KIAA0226 Run domain Beclin-1 interacting and cysteine-rich containing protein 1 GHVS(1)PAEDQTIQAPPVSVSALAR 99.40700000000001 3.6244999999999998e-06 8655900.0 27815.0 17227.0 20901.0 19987.0 23365.0 24159.0 20288.0 19930.0 33242.0 20190.0 True False 27418.352999353727 17187.11193992373 19182.600460193167 21456.91065467744 21990.716637357433 23125.775887379637 21338.413370053608 20856.020558042073 29497.935906221428 23679.814598516066 1.1578787023557162 0.7258127747757276 0.8100823754504934 0.9061266322592775 0.9286692911326897 0.9766029117824618 0.901122484776161 0.8807510072037916 1.2456996140531422 1.0 14.53137016495683 -8.244278858933372 24.913834293319667 1.122849811513109 0.9036518243665076 0.33530451615942336 0.11903030868649808 717.3409272447202 1041447.8290384775 0.07777377811699465 0.029233816371554675 5.6979828935171526e-09 8.244278858933372 -0.21919798714660133 GHYAYDCHR ddPTM_PC-9_AZD4547_30min_R2 4 GHYAYDCHR 9 0 Q16629-4;Q16629;A0A0B4J1Z1;C9JAB2;Q16629-3;Q16629-2;F8WEA1 Q16629-4 SRSF7 Serine/arginine-rich splicing factor 7 0 ;;; 153.08 5.695e-05 8662700.0 5366.51 5740.8 10709.5 11206.2 9167.5 12690.6 8691.5 13121.0 10805.100000000002 10112.6 False True 7072.948549657683 7596.401332537308 10567.485032537013 8622.78372406411 7894.750867568684 11897.054775832172 9465.026662333456 11093.450940584764 11376.235526951163 9758.560952035883 0.724794217551317 0.77843458373363 1.082893787770252 0.883612221765667 0.8090076914385249 1.2191402845467851 0.9699203303494058 1.1367916842565182 1.1657697874580362 1.0 13.252452700848744 -3.7243615543064568 0.36894640329990913 1.1031495075945976 4.397490659678908e-19 0.4791615829236543 0.11893040241582764 11.7998934699776 0.695912593505725 0.10210123084740723 6.743459869270648 0.00018864202323314567 3.7243615543064568 -1.1031495075945976 GHYAYDCHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GHYAYDCHR 9 0 Q16629-4;Q16629;A0A0B4J1Z1;C9JAB2;Q16629-3;Q16629-2;F8WEA1 Q16629-4 SRSF7 Serine/arginine-rich splicing factor 7 0 ;;; 130.75 0.0010539999999999998 6594900.0 3823.8500000000004 4032.3600000000006 6104.05 6885.6 9157.699999999999 6618.99 6508.8 4597.540000000001 6038.0599999999995 3387.4 False True 4471.152280519908 4432.666051861152 6249.593701738536 6499.822155416396 7363.3144240995 6271.878512334044 5892.2393443687615 4476.85944649629 6126.355204612754 4001.508805356356 1.1173665979529759 1.1077486686840863 1.5618093088719258 1.6243428345617625 1.8401345048255509 1.56737841084808 1.472504405458637 1.1187928514623378 1.5310113016400495 1.0 11.96632836855527 -9.17963425074189 0.772560788563342 0.9973496535285009 1.464185682352783 0.2283176910000173 0.23648047579583917 3.9782361167629086 3.331311619695848 0.31657604724000105 0.09144494005367668 6.612500977725635e-10 9.17963425074189 0.4668360288242821 GHYAYDCHR ddPTM_PC-9_Lapatinib_30min_R1 4 GHYAYDCHR 9 0 Q16629-4;Q16629;A0A0B4J1Z1;C9JAB2;Q16629-3;Q16629-2;F8WEA1 Q16629-4 SRSF7 Serine/arginine-rich splicing factor 7 0 ;;; 116.05 0.0016297999999999998 7714700.0 5878.0 4686.76 3426.4700000000003 3718.14 5602.4 2389.31 3388.84 4153.02 3726.81 5300.15 False True 5794.178642106816 4675.908095173677 3144.7588631566955 3991.5844189514405 5272.877846742186 2287.124781053647 3564.2975534785323 4345.984470544903 3307.0574127508903 6216.27386549405 0.9320983546541852 0.7522043263134209 0.5058912993864307 0.6421184949891524 0.8482377000813033 0.3679253569810141 0.5733816801836245 0.6991301484751263 0.5319999543630235 1.0 12.601834349489854 -10.697947384639834 3.761557635432181 1.0002518163500294 0.6455250282851168 0.3034337559817317 0.15878729383613804 126728815.39395761 214128031.87048638 420445.2828870378 0.04018284144613682 2.0047148865563104e-11 10.697947384639834 -0.35472678806491253 GHYEVT(ph)GSDDETGKLQGSGVSLASK ddPTM_PC-9_AZD4547_30min_R2 3 GHYEVTGSDDETGKLQGSGVSLASK 25 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GHY(0.031)EVT(0.436)GS(0.391)DDET(0.105)GKLQGS(0.028)GVS(0.009)LAS(0.001)K;GHY(0.019)EVT(0.288)GS(0.061)DDET(0.255)GKLQGS(0.288)GVS(0.085)LAS(0.003)K;GHY(0.014)EVT(0.454)GS(0.454)DDET(0.07)GKLQGS(0.006)GVS(0.002)LASK 62.376999999999995 0.001441 117382900.0 111924.0 133897.0 141960.0 162474.0 150965.0 152553.0 164417.0 148302.0 153165.0 146672.0 True False 147513.5038361779 177176.58675145413 140077.51764498375 125018.12949827687 130006.11559558263 143013.83679396735 179049.79448206656 125385.33354093465 161260.9892074552 141537.05792348253 1.0422253083424013 1.2518035159897063 0.9896879283778257 0.8832890221998533 0.9185305778071653 1.0104338672299038 1.2650382670725295 0.8858834243164798 1.1393552442967676 1.0 17.110820310411384 -5.2868547545406015 24.80683082480925 1.0085653528915075 1.147014436766984 0.16894686823482696 0.12005430546648362 1045.9518199719362 1020906.1589713043 0.03179692528820081 0.06622641799477036 5.1658910846175465e-06 5.2868547545406015 0.1384490838754764 GHYEVT(ph)GSDDETGKLQGSGVSLASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GHYEVTGSDDETGKLQGSGVSLASK 25 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GHY(0.023)EVT(0.482)GS(0.482)DDET(0.012)GKLQGSGVS(0.001)LASK 67.76 0.0062906 0.0 4111.7 5841.8 5375.5 5953.0 8041.2 5532.2 5854.2 6367.9 5847.9 4214.9 True False 4807.729600223259 6421.735296888786 5503.672306697273 5619.472709886404 6465.584584237193 5242.0816931185 5299.647795262349 6200.749372347764 5933.414474360133 4979.028004869959 0.9655960150296093 1.2897568141026168 1.1053708276623795 1.1286284600910117 1.2985636107917533 1.0528323375548903 1.064394052429268 1.2453734677296144 1.1916812816792142 1.0 12.281648414621861 -9.352315593793366 15.644897865691467 0.9999999999999964 1.153279710928607 0.15804793153513041 0.10286291946205625 0.0 0.0 0.09528261489529063 0.02310942855872553 4.44308279493158e-10 9.352315593793366 0.1532797109286106 GHYEVT(ph)GSDDETGKLQGSGVSLASK ddPTM_PC-9_Lapatinib_30min_R1 2 GHYEVTGSDDETGKLQGSGVSLASK 25 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GHY(0.122)EVT(0.468)GS(0.399)DDET(0.008)GKLQGS(0.002)GVSLASK;GHY(0.083)EVT(0.452)GS(0.452)DDET(0.012)GKLQGSGVSLASK 77.681 9.038e-05 245117000.0 148541.0 184762.0 166598.0 175713.0 191821.0 192390.0 164271.0 170092.0 177278.0 139338.0 True False 146422.77810091703 184334.19494074347 152900.9555268773 188635.52018138487 180538.46591459608 184161.9281829948 172776.1485958238 177995.09527137422 157311.08481990025 163422.38764378594 0.8959774741516859 1.1279617046260473 0.9356181716066813 1.154281998330341 1.1047352111151276 1.1269075849290313 1.0572367169939187 1.0891720396311466 0.962604249564591 1.0 17.318246109880242 -4.7484643845875025 24.967348169514896 1.0669845208681952 0.895977059545197 0.3316713818438465 0.07041417196288276 713.3034739194958 1372503.6223817782 0.016897029946332843 0.30763934858151826 1.7845783313791275e-05 4.7484643845875025 -0.17100746132299816 GHYEVTGS(ph)DDETGK ddPTM_PC-9_AZD4547_30min_R2 3 GHYEVTGSDDETGK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GHYEVT(0.002)GS(0.997)DDET(0.001)GK;GHYEVTGS(0.999)DDET(0.001)GK;GHYEVT(0.085)GS(0.912)DDET(0.003)GK 192.32 7.3167e-07 50009300.0 123997.0 178477.0 165141.0 135222.0 157178.0 209988.0 196576.0 207567.0 206156.0 175734.0 True False 163425.46670217736 236166.19994203968 162951.12243878742 104048.65705907425 135356.54778976904 196857.4171644713 214070.88318182822 175492.28956515164 217052.98528418445 169581.60614926627 0.9636980708764472 1.3926404243050123 0.9609009263384222 0.6135609835390419 0.7981794185309684 1.1608418013873318 1.2623473031232075 1.0348545078095486 1.2799323594867578 1.0 17.37162016935944 -6.795388779262843 24.31967231182738 1.1569458655909939 0.9530023222783133 0.20240384226374264 0.19960903205985842 258.92559957779974 185479.3115380936 0.0776427618982161 0.06847888569113549 1.6018108119001638e-07 6.795388779262843 -0.2039435433126806 GHYEVTGS(ph)DDETGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GHYEVTGSDDETGK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GHYEVT(0.2)GS(0.784)DDET(0.016)GK;GHYEVT(0.019)GS(0.928)DDET(0.052)GK;GHYEVTGS(1)DDETGK;GHYEVT(0.29)GS(0.71)DDETGK;GHYEVT(0.014)GS(0.983)DDET(0.003)GK 155.56 1.9273e-12 44112400.0 394016.0 743540.0 541676.0 467877.0 580970.0 326874.0 503308.0 337406.0 306512.5 327196.1 True False 460715.12662926933 817353.73731533 554591.6101576707 441663.36856770125 467133.0990280397 309732.15201121004 455631.02260563517 328549.4500112079 310994.6654478205 386514.16284709756 1.1919747603440995 2.114679915723217 1.4348545628250715 1.142683531476233 1.2085795138452262 0.8013474842155733 1.1788210275385944 0.8500321116077184 0.8046138934651352 1.0 18.560161753515565 -5.841907449357778 1.7437939018181567 0.9613740047347514 1.6740425387303317 0.553066035350013 0.24708341384178273 0.24607223618881904 1.5265601713341583 0.0761019888940518 0.14668533969693107 1.4391052271490908e-06 5.841907449357778 0.7126685339955803 GHYEVTGS(ph)DDETGK ddPTM_PC-9_Lapatinib_30min_R1 4 GHYEVTGSDDETGK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GHYEVTGS(1)DDETGK;GHYEVTGS(1)DDETGK;GHYEVT(0.001)GS(0.999)DDETGK;GHYEVTGS(1)DDETGK 179.81 3.0934e-05 137318000.0 156576.0 373422.0 281543.0 297328.0 360261.0 313270.0 347581.0 362473.0 288095.0 269481.0 True False 154343.19752747833 372557.36430197925 258395.62132740865 319194.49297713256 339071.1562803776 299872.17236803734 365577.0434531057 379314.8188527445 255646.7073251569 316060.4317891387 0.48833445127496744 1.1787535763114212 0.8175513140467978 1.0099160188140373 1.072804825206942 0.9487811260350949 1.1566681769801614 1.200133837397926 0.8088538823983917 1.0 18.269840907228357 -4.751159607329841 24.999882663643824 1.024570109507862 0.48833334586072236 0.6002470779188976 0.1305084003470699 292.68121854331173 711738.0817269185 0.03152009472731847 0.4293579274171345 1.7735375692740815e-05 4.751159607329841 -0.5362367636471397 GHYEVTGS(ph)DDETGKLQGSGVSLASK ddPTM_PC-9_AZD4547_30min_R2 7 GHYEVTGSDDETGKLQGSGVSLASK 25 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GHYEVT(0.072)GS(0.927)DDET(0.001)GKLQGSGVSLASK;GHYEVT(0.031)GS(0.968)DDET(0.001)GKLQGSGVSLASK;GHY(0.008)EVT(0.067)GS(0.919)DDET(0.006)GKLQGSGVSLASK;GHY(0.002)EVT(0.068)GS(0.93)DDETGKLQGSGVSLASK;GHY(0.134)EVT(0.134)GS(0.698)DDET(0.026)GKLQGS(0.005)GVS(0.002)LASK;GHY(0.011)EVT(0.453)GS(0.526)DDET(0.01)GKLQGSGVSLASK;GHY(0.003)EVT(0.035)GS(0.958)DDET(0.004)GKLQGSGVSLASK 87.73899999999999 3.8707e-06 802952100.0 469791.0 544748.0 586264.0 602730.0 591995.0 634719.0 600460.0 721098.0 628501.0 627927.0 True False 619174.7657401608 720827.1378722537 578489.7563019079 463779.9105856724 509806.7128275226 595029.9205917293 653899.7767548467 609668.8732835753 661722.2797497784 605943.4668561046 1.0218358635875817 1.1895947019813828 0.9546926205894449 0.7653847857985204 0.8413436908109914 0.9819891675357119 1.0791432081074495 1.0061481089098951 1.092052833217393 1.0 19.208823674255648 -7.013338462231995 23.65525788949264 1.0428080939255406 0.9525780113705485 0.1351318036194865 0.10738444176968424 758.4171176141646 1345022.9734121838 0.0457800226388004 0.037158050113646666 9.697539065130863e-08 7.013338462231995 -0.0902300825549921 GHYEVTGS(ph)DDETGKLQGSGVSLASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 10 GHYEVTGSDDETGKLQGSGVSLASK 25 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GHYEVT(0.102)GS(0.898)DDETGKLQGSGVSLASK;GHY(0.005)EVT(0.088)GS(0.895)DDET(0.011)GKLQGSGVSLASK;GHY(0.016)EVT(0.08)GS(0.665)DDET(0.212)GKLQGS(0.018)GVS(0.009)LASK;GHY(0.002)EVT(0.155)GS(0.829)DDET(0.01)GKLQGS(0.003)GVS(0.001)LASK;GHY(0.049)EVT(0.176)GS(0.771)DDET(0.003)GKLQGSGVSLASK;GHY(0.03)EVT(0.359)GS(0.599)DDET(0.012)GKLQGSGVSLASK;GHY(0.003)EVT(0.047)GS(0.949)DDET(0.001)GKLQGSGVSLASK;GHY(0.022)EVT(0.166)GS(0.795)DDET(0.013)GKLQGS(0.001)GVS(0.002)LASK;GHY(0.003)EVT(0.028)GS(0.927)DDET(0.042)GKLQGS(0.001)GVSLASK;GHY(0.001)EVT(0.012)GS(0.732)DDET(0.238)GKLQGS(0.012)GVS(0.004)LASK 82.665 1.4555e-05 358762000.0 578661.6 749789.3 642580.0 771865.0 934101.0 632829.5 808907.0 625405.1 595320.6 593501.8 True False 676617.5797924332 824223.426519145 657901.5441982204 728619.906470092 751070.6145501331 599642.8069873338 732281.4729804735 608988.8787964784 604026.0375390764 701098.9781823355 0.9650813948504495 1.1756163568459637 0.9383861119066119 1.0392539843077608 1.0712761506190662 0.8552898030773968 1.0444765942734384 0.868620405602842 0.8615417456534743 1.0 19.41925860662238 -6.749255419082388 24.99937115056244 0.9251801593028878 1.0401165912527799 0.3175089649989036 0.08202097748208086 268.67343337176874 551270.1856095721 0.026246802103472754 0.026059945134733465 1.7813308156051656e-07 6.749255419082388 0.11493643194989211 GHYEVTGS(ph)DDETGKLQGSGVSLASK ddPTM_PC-9_Lapatinib_30min_R1 10 GHYEVTGSDDETGKLQGSGVSLASK 25 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GHY(0.003)EVT(0.056)GS(0.939)DDET(0.002)GKLQGSGVSLASK;GHY(0.021)EVT(0.267)GS(0.692)DDET(0.016)GKLQGS(0.003)GVS(0.001)LASK;GHYEVT(0.05)GS(0.949)DDETGKLQGSGVSLASK;GHY(0.08)EVT(0.435)GS(0.436)DDET(0.048)GKLQGS(0.001)GVSLASK;GHY(0.008)EVT(0.079)GS(0.899)DDET(0.011)GKLQGS(0.001)GVS(0.002)LASK;GHY(0.003)EVT(0.208)GS(0.786)DDET(0.002)GKLQGSGVSLASK;GHY(0.012)EVT(0.107)GS(0.878)DDET(0.003)GKLQGSGVSLASK;GHY(0.015)EVT(0.039)GS(0.834)DDET(0.108)GKLQGS(0.002)GVS(0.002)LASK;GHY(0.006)EVT(0.103)GS(0.889)DDET(0.001)GKLQGSGVSLASK;GHY(0.005)EVT(0.116)GS(0.862)DDET(0.016)GKLQGS(0.001)GVSLASK 91.691 2.0338e-06 1051692900.0 613070.0 913995.0 763889.0 733189.0 860576.0 808445.2 692232.0 739595.0 803902.0 599913.0 True False 604327.5093767326 911878.7007331875 701084.9951168114 787110.1649068064 809958.6116375143 773869.8833738073 728072.3858428113 773959.2837242924 713358.09129665 703607.162716174 0.8588990297424111 1.296005426114497 0.9964153753216124 1.1186784424824232 1.1511517428429605 1.0998607239676101 1.0347711399528579 1.099987784002275 1.0138584839626048 1.0 19.424410643947233 -8.319002763740341 1.2346521163232855 0.9968027232074123 1.0925402560132162 0.06270181543335551 0.10649715861567477 1.1549117376512994 3.60626259332753 0.09271712890184311 0.029507736869021986 4.797303957439593e-09 8.319002763740341 0.095737532805804 GHYEVTGSDDET(ph)GKLQGSGVSLASK ddPTM_PC-9_AZD4547_30min_R2 1 GHYEVTGSDDETGKLQGSGVSLASK 25 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GHY(0.053)EVT(0.157)GS(0.195)DDET(0.486)GKLQGS(0.105)GVS(0.004)LASK 48.852 0.019437 6989300.0 16533.0 21942.0 24398.0 20486.0 17713.0 24774.0 26105.0 31701.0 25173.0 26918.0 True False 21790.150092236956 29034.32240080366 24074.466578630003 15763.269205544904 15253.855698635845 23224.877863652306 28428.294427914036 26802.33886651 26503.59338830195 25975.609013201534 0.8388696519555168 1.117753288712022 0.9268104769514618 0.6068488787898512 0.5872376540193305 0.8941033048291099 1.094422633689396 1.031827159582218 1.0203261596227475 1.0 14.664869953896481 -7.072441691676524 5.772138077640404 1.0359117184861208 0.8189769624472164 0.34593420259943386 0.1432924993772912 0.30958911987627635 18.610502599743526 0.0634861092235959 0.049403808671514206 8.463661942000845e-08 7.072441691676524 -0.21693475603890444 GHYEVTGSDDET(ph)GKLQGSGVSLASK ddPTM_PC-9_Lapatinib_30min_R1 2 GHYEVTGSDDETGKLQGSGVSLASK 25 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GHY(0.034)EVT(0.108)GS(0.352)DDET(0.482)GKLQGS(0.017)GVS(0.005)LAS(0.001)K;GHY(0.082)EVT(0.272)GS(0.239)DDET(0.289)GKLQGS(0.085)GVS(0.033)LASK 58.516000000000005 0.0031334 14787700.0 18894.3 27900.0 30046.0 27043.0 33853.0 26619.1 23822.8 21868.5 31421.0 24309.8 True False 18624.863817209734 27835.39926417089 27575.73386091401 29031.832432803443 31861.833097558774 25480.66314515283 25056.228018144364 22884.590344884233 27882.036102201528 28511.71653922761 0.6532354441580137 0.976279321024877 0.9671719983247646 1.018242180994618 1.1174996445311152 0.8936909536854952 0.8788046129622171 0.8026381124194559 0.977915028856304 1.0 14.799267278456425 -4.759040449007383 24.979552626698993 0.9554616719749714 0.6532350453370293 0.5591558212841072 0.0814266527307102 54.057330369551245 562764.3207085289 0.02239355269625292 0.14631927864941838 1.74164465378912e-05 4.759040449007383 -0.3022266266379422 GHYEVTGSDDET(ph)GKLQGSGVSLASKK ddPTM_PC-9_Lapatinib_30min_R1 1 GHYEVTGSDDETGKLQGSGVSLASKK 26 2 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GHY(0.001)EVT(0.099)GS(0.395)DDET(0.402)GKLQGS(0.086)GVS(0.011)LAS(0.006)KK 55.208 0.0023343000000000005 32086000.0 46639.0 18753.0 21131.0 19230.0 16252.0 14826.0 9552.3 7342.3 18063.0 9546.8 True False 45973.91930745492 18709.578580680878 19393.690748018857 20644.23834939947 15296.089312661374 14191.926541094024 10046.871354237133 7683.450062383955 16028.554728177529 11196.951659688611 4.105931748635722 1.6709528762224908 1.7320509489953624 1.843737382891728 1.3660940743122543 1.2674812727992704 0.8972863025217828 0.6862090947526367 1.4315105767477507 1.0 13.450818395399828 -2.3558689965030752 0.8535044516127566 1.1632213017766757 199.99999999879395 0.8649215048272483 0.3337058057788684 49.55288366579409 0.6708059358271683 0.12175703741349654 18479.27539586462 0.004406877754721442 2.3558689965030752 198.83677869701728 up GHYEVTGSDDETGKLQGS(ph)GVSLASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GHYEVTGSDDETGKLQGSGVSLASK 25 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GHY(0.057)EVT(0.23)GS(0.212)DDET(0.212)GKLQGS(0.271)GVS(0.016)LAS(0.001)K;GHY(0.027)EVT(0.247)GS(0.247)DDET(0.146)GKLQGS(0.25)GVS(0.079)LAS(0.002)K 43.523 0.028515 104191000.0 36948.0 38888.0 35913.0 42004.0 48321.0 40994.0 47330.0 33341.0 36495.0 31020.0 True False 43202.56664373592 42748.54363816139 36769.302120810935 39650.6520588054 38852.84692520086 38844.202474187405 42846.559760474 32465.83407770957 37028.670333243186 36643.680445815124 1.1789909233495088 1.1666007103564149 1.0034281948065116 1.0820597597295576 1.0602877891223952 1.0600518834789585 1.1692755541799644 0.8859872611790914 1.0105063105764538 1.0 15.161276792762251 -1.5228787452803376 0.25789653126973283 0.9926994485695309 2.2228374289375994 0.3716610852780742 0.06976078114956823 58.29606933700842 0.8021182652471616 0.08935882728976854 31.430677682714087 0.029999999999999995 1.5228787452803376 1.2301379803680685 GHYTEGAELVDSVLDVVR ddPTM_PC-9_AZD4547_30min_R2 2 GHYTEGAELVDSVLDVVR 18 0 P68371;A0A0B4J269;Q13509;Q13509-2;G3V2A3;Q5JP53;P07437;Q5ST81;Q9BVA1;Q13885 P68371;A0A0B4J269;Q5JP53 TUBB4B;TUBB3;TUBB;TUBB2B;TUBB2A Tubulin beta-4B chain;Tubulin beta-3 chain;Tubulin beta chain;Tubulin beta-2B chain;Tubulin beta-2A chain 0 ; 142.39 0.00013226 13696000.0 37861.0 33821.0 69137.0 78626.0 72506.0 68051.0 57779.0 85397.0 56018.0 63454.0 False True 49900.010442278035 44752.97684429773 68220.19820668675 60499.99045959065 62439.79344466157 63795.76021229531 62921.21906724557 72200.85587783837 58978.997116986415 61232.49477389445 0.8149269538426868 0.7308697287208603 1.1141175687614056 0.98803732696163 1.0197166337126253 1.0418611955607218 1.0275788909073011 1.1791264776071173 0.9631976834321508 1.0 15.90200984305287 -5.257954930467024 24.999863563167125 1.0449009970280096 0.7728983186068601 0.7466114182959614 0.06261692659275223 131.02204936942735 940032.4571269379 0.015430984897981118 0.03759205840150549 5.521347348820427e-06 5.257954930467024 -0.27200267842114956 GHYTEGAELVDSVLDVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GHYTEGAELVDSVLDVVR 18 0 P68371;A0A0B4J269;Q13509;Q13509-2;G3V2A3;Q5JP53;P07437;Q5ST81;Q9BVA1;Q13885 P68371;A0A0B4J269;Q5JP53 TUBB4B;TUBB3;TUBB;TUBB2B;TUBB2A Tubulin beta-4B chain;Tubulin beta-3 chain;Tubulin beta chain;Tubulin beta-2B chain;Tubulin beta-2A chain 0 ; 231.21 1.2105e-35 24615000.0 12552.900000000001 16594.6 21212.2 23262.2 29152.0 21761.3 19813.0 19594.1 18456.0 15071.099999999999 False True 14677.85803892369 18242.002218109275 21717.979295716472 21958.894351069946 23439.87486938301 20620.099119420756 17936.169206301955 19079.775636665025 18725.88408467836 17803.37112723804 0.8244426257265114 1.0246375300349808 1.2198801642959254 1.2334121551549424 1.316597553455563 1.1582131817649581 1.0074591535566397 1.0716945403375975 1.0518167571100585 1.0 14.119862825688243 -7.256101134276966 23.986195468495318 1.0387171577571956 1.1420944139102027 0.11568340441400837 0.12788068059603594 613.20881126973 2755328.367955298 0.05528363366628447 0.04146168243951933 5.544965721507647e-08 7.256101134276966 0.10337725615300708 GHYTEGAELVDSVLDVVR ddPTM_PC-9_Lapatinib_30min_R1 2 GHYTEGAELVDSVLDVVR 18 0 P68371;A0A0B4J269;Q13509;Q13509-2;G3V2A3;Q5JP53;P07437;Q5ST81;Q9BVA1;Q13885 P68371;A0A0B4J269;Q5JP53 TUBB4B;TUBB3;TUBB;TUBB2B;TUBB2A Tubulin beta-4B chain;Tubulin beta-3 chain;Tubulin beta chain;Tubulin beta-2B chain;Tubulin beta-2A chain 0 ; 153.92 3.0238e-13 1427000.0 7803.299999999999 8226.0 9814.9 7157.6 10856.0 11667.4 6721.0 9908.0 11062.6 7409.2 False True 7692.023511050034 8206.953202403936 9007.956808609639 7683.993781053653 10217.471423717196 11168.412500037799 7068.980493894433 10368.361850932306 9816.613493657578 8689.870347861575 0.8851712629916172 0.9444275776132292 1.0366042815387158 0.8842472296430233 1.1757910089224215 1.285221994455435 0.813473643554876 1.1931549535124857 1.1296616751104087 1.0 13.08511893697305 -6.259099011036794 24.96355308522583 1.1041880213104494 0.9451702069774157 0.28434219367733415 0.12550160915434186 287.94116106523 3071322.28024404 0.03791767972937203 0.04663027087880863 5.506821368433094e-07 6.259099011036794 -0.15901781433303364 GHYTIGK ddPTM_PC-9_AZD4547_30min_R2 2 GHYTIGK 7 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;F8VRZ4;F8VS66;F8VWV9;P68363;P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8;C9JDL2;Q71U36-2;Q71U36 Q9BQE3;P68363;P68366-2;Q71U36-2 TUBA1C;TUBA1B;TUBA1A;TUBA3E;TUBA4A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain;Tubulin alpha-1A chain 0 ; 107.66 0.008287899999999999 36194000.0 226440.0 235660.0 549000.0 805720.0 669790.0 616260.0 513980.0 795310.0 532880.0 564390.0 False True 298443.2097554064 311832.48641752725 541719.9012897725 619973.7022499094 576801.2199169709 577725.1647797833 559723.2242888041 672413.1139056823 561046.9489039187 544630.8778869457 0.5479733556666928 0.5725574863242647 0.9946551385252572 1.1383374087331921 1.0590681566841003 1.0607646173519147 1.0277111471542222 1.2346217249277254 1.030141645807274 1.0 19.05491925283677 -5.299616063973568 3.4738164154530393 1.083980290746608 0.5443758791597468 0.9115940874970099 0.06369689393614927 0.056201203517895475 1.402761852590832 0.016601883766093624 0.04275233066998874 5.016305017869409e-06 5.299616063973568 -0.5396044115868612 GHYTIGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GHYTIGK 7 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;F8VRZ4;F8VS66;F8VWV9;P68363;P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8;C9JDL2;Q71U36-2;Q71U36 Q9BQE3;P68363;P68366-2;Q71U36-2 TUBA1C;TUBA1B;TUBA1A;TUBA3E;TUBA4A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain;Tubulin alpha-1A chain 0 ; 107.66 0.008287899999999999 20398000.0 183785.0 260400.0 475570.0 440840.0 512230.0 395350.0 448860.0 370710.0 374940.0 288680.0 False True 214896.17058078977 286250.79107635294 486909.39240926824 416141.16402256436 411862.2085738223 374617.1500261011 406340.7313350173 360979.255299713 380422.7881832086 341015.39881037694 0.6301655917311925 0.8394072293360685 1.4278223039423985 1.220300213639213 1.2077525238173776 1.0985344102727999 1.1915612396171142 1.0585423900474273 1.1155589733199829 1.0 18.37947736115187 -5.049053728094331 5.566593374997109 1.168825527611102 0.673620413236458 0.7197699750663 0.11080419084505011 0.08778433782809403 6.480164300132795 0.02875309138436472 0.08499658379585115 8.93194976612973e-06 5.049053728094331 -0.4952051143746439 GHYTIGK ddPTM_PC-9_Lapatinib_30min_R1 2 GHYTIGK 7 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;F8VRZ4;F8VS66;F8VWV9;P68363;P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8;C9JDL2;Q71U36-2;Q71U36 Q9BQE3;P68363;P68366-2;Q71U36-2 TUBA1C;TUBA1B;TUBA1A;TUBA3E;TUBA4A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain;Tubulin alpha-1A chain 0 ; 110.35 0.0079551 40499000.0 558860.0 599330.0 779910.0 702570.0 813240.0 832020.0 810610.0 779010.0 847600.0 637840.0 False True 550890.5539176284 597942.2882077255 715788.8103396602 754239.3415048135 765406.8220913571 796436.4441333495 852579.4194548073 815205.6485158212 752134.3623763089 748089.7941316218 0.73639629659311 0.7992921343109798 0.956822049912529 1.0082203332025537 1.0231483280424067 1.064626800660806 1.1396752450612917 1.0897163080029812 1.0054065277676751 1.0 19.512851923391068 -5.220565354257623 1.0344635895296321 1.066119971497668 0.6674851041411491 0.8884008997697997 0.03965110934916994 0.30724562166849945 0.4273052539952505 0.014202255238363886 0.11545794133189902 6.017756986281301e-06 5.220565354257623 -0.39863486735651876 GIAPAS(ph)PMLGNASNPNK ddPTM_PC-9_AZD4547_30min_R2 3 GIAPASPMLGNASNPNK 17 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;H0YKP9 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 GIAPAS(1)PMLGNASNPNK;GIAPAS(1)PMLGNASNPNK;GIAPAS(1)PMLGNASNPNK 149.6 6.1031000000000006e-05 20323800.0 82462.0 99438.0 141246.0 147409.0 157145.0 160976.0 152546.0 188132.0 145297.0 151454.0 True False 108683.20068384706 131579.38888392624 139372.98575150294 113426.13249634717 135328.1292701481 150910.14527243492 166122.2984792405 159060.52224328156 152977.10279029532 146151.64155900988 0.743633116429728 0.9002936092975734 0.9536190238084326 0.7760852446570056 0.9259432725256685 1.0325586744197037 1.1366433979612012 1.0883252527756222 1.0467012286586572 1.0 17.157106507862288 -6.707894905451691 2.8672570320594075 1.075638336293138 0.854865077065648 0.7156434809470025 0.06475329878716246 0.14207603385718376 2.381912730100035 0.02352304709670854 0.022543971861778634 1.959318750002864e-07 6.707894905451691 -0.22077325922749014 GIAPAS(ph)PMLGNASNPNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GIAPASPMLGNASNPNK 17 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;H0YKP9 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 GIAPAS(0.684)PMLGNAS(0.316)NPNK;GIAPAS(0.76)PMLGNAS(0.24)NPNK 79.346 0.0056784999999999995 66692000.0 353100.0 439760.0 407600.0 495950.0 518520.0 391990.0 487870.0 422510.0 362950.0 325320.0 True False 412872.8559571062 483416.4665274083 417318.72983160726 468163.5293915952 416919.72822696477 371433.35434104304 441655.4217270762 411419.5601863485 368257.4571160604 384297.9407682973 1.0743561496366107 1.2579210431389534 1.085924970082572 1.2182306479593201 1.084886708977543 0.9665244461067497 1.1492526367539426 1.0705744593994677 0.9582602924695137 1.0 18.55186572028503 -6.513703841475186 23.355233957227476 1.0391707545240498 1.1597663876029851 0.41542080591148534 0.07229275227569042 189.6582799008738 482788.6067144444 0.022354443597662893 0.02357958203100616 3.064052191153336e-07 6.513703841475186 0.12059563307893528 GIAPAS(ph)PMLGNASNPNK ddPTM_PC-9_Lapatinib_30min_R1 4 GIAPASPMLGNASNPNK 17 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;H0YKP9 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 GIAPAS(1)PMLGNASNPNK;GIAPAS(1)PMLGNASNPNK;GIAPAS(1)PMLGNASNPNK;GIAPAS(0.998)PMLGNAS(0.002)NPNK 245.04 5.788599999999999e-131 14699400.0 82555.0 152318.0 140616.0 143351.0 132404.0 119821.0 121181.0 134969.0 123406.0 98246.0 True False 81377.75056126702 151965.31702938967 129055.09527345667 153893.51074491753 124616.25703627952 114696.5351463934 127455.15923681318 141240.15246855863 109506.71675720968 115227.69019543375 0.7062343298146913 1.3188263756016152 1.1200007138437882 1.3355601460369813 1.0814783913911852 0.9953903870836995 1.1061157176772427 1.225748361604802 0.9503507062536711 1.0 16.81412792478705 -6.494457277013774 24.4962274089754 1.0689748400405636 1.1436081263715348 0.019586981380717017 0.175954945314579 2222.2254425056562 1915319.3350824008 0.05313023201028205 0.06010524707244817 3.202895158534043e-07 6.494457277013774 0.0746332863309711 GIAPAS(ph)PMLGNASNPNKADIPER ddPTM_PC-9_AZD4547_30min_R2 2 GIAPASPMLGNASNPNKADIPER 23 1 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;H0YKP9 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 GIAPAS(1)PMLGNASNPNKADIPER;GIAPAS(1)PMLGNASNPNKADIPER 93.851 1.6549e-05 136654000.0 41438.0 30450.0 67118.0 96138.0 93726.0 77213.0 69008.0 76652.0 55374.0 87912.0 True False 54614.422036056036 40292.36701779562 66227.97146587784 73974.86941729364 80713.76272852393 72384.85890393911 75149.57831379019 64807.194687729796 58300.956591738446 84834.22763833035 0.6437781489435025 0.4749541327773044 0.7806751273580793 0.8719931975177179 0.951429216431686 0.8532506385575167 0.8858403076900958 0.7639274440502855 0.6872338938510772 1.0 16.372358838691483 -5.41066495257456 4.512358005943367 0.8524466172971146 0.5620663081255782 0.6252102723772295 0.09121862746694971 0.14187680855177853 4.599772088014269 0.024709110417881198 0.05361145892594763 3.884499299129122e-06 5.41066495257456 -0.29038030917153634 GIAPAS(ph)PMLGNASNPNKADIPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GIAPASPMLGNASNPNKADIPER 23 1 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;H0YKP9 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 GIAPAS(1)PMLGNASNPNKADIPER;GIAPAS(1)PMLGNASNPNKADIPER 110.33 1.5311e-06 135305000.0 76258.0 70432.0 130685.0 152760.0 177085.0 161294.0 147390.0 160131.0 155606.0 121098.0 True False 89166.97323584513 77424.0234911279 133801.02602562227 144201.35245460185 142386.46546530872 152835.4586981407 133428.15218880784 155927.7309228188 157881.4433723698 143052.1087887595 0.6233181320487569 0.5412295152213205 0.935330678859142 1.0080337415195981 0.9953468471797664 1.0683901131707743 0.9327241193335846 1.0900065175066542 1.1036638656303088 1.0 17.126181239603405 -5.3563040743097465 3.578583847880556 1.0257367062693017 0.5784560706162436 0.9163941496675195 0.05295446738027571 0.05865496044676202 1.387141846517336 0.01457297720675983 0.034546425133667215 4.402465139061329e-06 5.3563040743097465 -0.4472806356530581 GIAPAS(ph)PMLGNASNPNKADIPER ddPTM_PC-9_Lapatinib_30min_R1 4 GIAPASPMLGNASNPNKADIPER 23 1 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;H0YKP9 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 GIAPAS(1)PMLGNASNPNKADIPER;GIAPAS(1)PMLGNASNPNKADIPER;GIAPAS(0.984)PMLGNAS(0.016)NPNKADIPER;GIAPAS(0.966)PMLGNAS(0.034)NPNKADIPER 101.05 5.0345e-06 120151000.0 500098.0 289116.0 345584.0 316055.0 240921.0 246152.0 190156.0 214368.0 291652.0 166338.0 True False 492966.5108132591 288446.56966523384 317171.4175128174 339298.73902857304 226750.50044891017 235624.65276833807 200001.34723954622 224328.3198688587 258803.08052828646 195089.30166854704 2.526876187453886 1.478536071420764 1.6257755540674679 1.7391970555363157 1.1622907996982577 1.2077784417346462 1.0251784466343759 1.1498750467105991 1.3265877642434125 1.0 17.573775139862363 -1.5228787452804764 0.4494928919070788 1.1234384663684904 29.011762759775706 0.7867078862453144 0.2012079350482617 41.16487901617046 0.4964370360724602 0.12830635945881685 1053.2952771236874 0.02999999999999041 1.5228787452804764 27.888324293407216 up GIAPASPMLGNAS(ph)NPNK ddPTM_PC-9_AZD4547_30min_R2 2 GIAPASPMLGNASNPNK 17 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;H0YKP9 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 GIAPAS(0.095)PMLGNAS(0.905)NPNK;GIAPAS(0.121)PMLGNAS(0.879)NPNK 92.38 0.0018105 57331000.0 244030.0 296240.0 342260.0 364470.0 349580.0 397410.0 377780.0 394970.0 358530.0 375710.0 True False 321626.4638606771 391993.78671105957 337721.4087712885 280447.0725053672 301046.85119003674 372559.8898762434 411401.6881431657 333936.4620076799 377481.1638464982 362556.5072572232 0.8871071334336652 1.0811936315156288 0.9315000614005946 0.773526517637148 0.8303446363919565 1.0275912372796638 1.1347243254726314 0.9210604562967113 1.0411650495592577 1.0 18.467846342354626 -6.786673044185783 24.50435357757619 1.0268380881509045 0.9054020210577255 0.3280475861140114 0.08871173953168404 250.5910450353925 243346.1729848161 0.034044499064274786 0.03003744663321095 1.6342818434768636e-07 6.786673044185783 -0.121436067093179 GIASTSDPPTANIKPT(ph)PVVSTPSK ddPTM_PC-9_AZD4547_30min_R2 1 GIASTSDPPTANIKPTPVVSTPSK 24 1 P12270 P12270 TPR Nucleoprotein TPR 1 GIASTSDPPT(0.002)ANIKPT(0.584)PVVS(0.199)T(0.199)PS(0.016)K 99.881 2.7293000000000003e-06 42875000.0 59522.0 65015.0 67845.0 72324.0 78586.0 93639.0 76296.0 103150.0 85139.0 92341.0 True False 78448.75786548891 86029.82731238035 66945.33097086451 55650.81919466125 67675.69039310077 87783.7385272679 83086.1961950633 87210.53765119426 89639.27372528665 89108.16969641292 0.8803767166664954 0.9654538703407294 0.7512816299441892 0.6245310546076842 0.7594779538584224 0.9851368154720572 0.932419513027075 0.9787041743570337 1.0059602170113378 1.0 16.443270087841867 -6.766248083558848 24.98487743698313 0.976111646350443 0.7935905607406089 0.5403486589263067 0.08488960439429263 111.86611140771147 581225.7966700952 0.03378156439718326 0.03074206411003163 1.71297851725474e-07 6.766248083558848 -0.18252108560983415 GIASTSDPPTANIKPT(ph)PVVSTPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GIASTSDPPTANIKPTPVVSTPSK 24 1 P12270 P12270 TPR Nucleoprotein TPR 1 GIASTSDPPT(0.001)ANIKPT(0.531)PVVS(0.201)T(0.239)PS(0.028)K 61.361000000000004 0.0024933000000000004 21124000.0 35710.0 33220.0 38832.0 33010.0 41780.0 35298.0 36435.0 34495.0 31193.0 28235.0 True False 41754.99769535048 36517.862056668426 39757.90215118008 31160.55671986394 33593.50892023952 33446.91074142236 32983.613033443304 33589.54280047364 31649.138613641753 33353.78199186298 1.2518819516640443 1.0948642065711576 1.1920058169379248 0.9342435807569257 1.0071873986714615 1.00279214961536 0.9889017395835356 1.007068488025381 0.9488920513230824 1.0 15.02556273770745 -5.755505567737295 24.99999968490075 0.9863835791227675 1.171112058126592 0.8144118278806299 0.04268481472938658 56.639155396540396 238625.77208083167 0.010988922854244887 0.018408310255610127 1.7558783833622934e-06 5.755505567737295 0.1847284790038244 GIASTSDPPTANIKPTPVVS(ph)TPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GIASTSDPPTANIKPTPVVSTPSK 24 1 P12270 P12270 TPR Nucleoprotein TPR 1 GIASTSDPPT(0.001)ANIKPT(0.149)PVVS(0.403)T(0.35)PS(0.097)K 59.537 0.0022622 26802000.0 42920.0 47182.0 52117.0 48890.0 58052.0 39414.0 53016.0 42842.0 34132.0 32541.0 True False 50185.508291359336 51865.91714502497 53359.66693482318 46150.851803518606 46677.12732976886 37347.06045561846 47993.94067739894 41717.44289485118 34631.11592860001 38440.425705585745 1.3055398677353076 1.3492544942728972 1.3881133196469657 1.2005811839074525 1.2142718628369988 0.971556890177509 1.2485278140513667 1.0852492429288902 0.9009035486193326 1.0 15.230336692766645 -6.492942416760456 0.5190542109562013 0.9877008436551029 1.3960883630831233 0.6683162419096201 0.0919461378770283 0.6919521836029543 0.3894581982674769 0.07941897784669313 0.1333751697682116 3.2140866671337257e-07 6.492942416760456 0.40838751942802043 GIASTSDPPTANIKPTPVVST(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 1 GIASTSDPPTANIKPTPVVSTPSK 24 1 P12270 P12270 TPR Nucleoprotein TPR 1 GIASTSDPPTANIKPT(0.003)PVVS(0.167)T(0.664)PS(0.167)K 93.876 4.9194e-06 39432000.0 152490.0 167770.0 194460.0 205700.0 222450.0 223750.0 204780.0 249370.0 241790.0 250050.0 True False 200978.6480109607 221998.3715788362 191881.33334209293 158279.04303331973 191566.6572665017 209758.87712893344 223005.0232885748 210835.59645252855 254570.52577593166 241295.82560929644 0.8329139035185098 0.9200257444084157 0.7952119886764435 0.6559543358599308 0.7939078796028752 0.8693017237213739 0.9241976015352296 0.8737639613953009 1.055014213914042 1.0 17.880443431744062 -7.690857162062465 1.063524616480532 1.0148196649743415 0.8028031897399031 0.5667118157418137 0.0706252194500873 0.43943911930403834 0.9026452993028677 0.06625857528939949 0.027575859171288464 2.0377121639154687e-08 7.690857162062465 -0.21201647523443845 GIASTSDPPTANIKPTPVVST(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 2 GIASTSDPPTANIKPTPVVSTPSK 24 1 P12270 P12270 TPR Nucleoprotein TPR 1 GIASTSDPPTANIKPT(0.007)PVVS(0.176)T(0.686)PS(0.131)K;GIASTSDPPTANIKPT(0.02)PVVS(0.222)T(0.709)PS(0.048)K 98.26700000000001 3.3182e-06 51640000.0 104897.0 163950.0 155820.0 163964.0 188863.0 161154.0 145889.0 144960.0 150798.0 138917.0 True False 103401.14954424623 163570.38384805832 143009.08108259412 176022.45952786994 177754.44965894453 154261.81908832229 153442.41857964054 151695.37080249735 133813.54126666216 162928.61835473246 0.6346408052090551 1.003938936571159 0.8777407095617235 1.080365507946733 1.0909958695649948 0.9468061574821645 0.941776958088245 0.9310541778008711 0.8213016388276233 1.0 17.313880509436927 -4.757586335449846 24.99984779053846 0.9672087380785223 0.6346403283718562 0.6136154769300299 0.07887693375601548 79.93381307960493 518564.0788534435 0.0206465768170194 0.15134354329774943 1.7474858369288563e-05 4.757586335449846 -0.332568409706666 GIAYIEFK ddPTM_PC-9_AZD4547_30min_R2 3 GIAYIEFK 8 0 P19338;H7BY16 P19338 NCL Nucleolin 0 ;; 124.08 0.015285 6299200.0 66702.0 68318.0 81494.0 113074.0 102181.0 82321.0 69634.0 91403.0 86507.0 84164.0 False True 87911.84851221109 90400.4574686948 80413.3363127664 87006.53627588518 87994.93192244714 77173.4548564514 75831.29110106752 77278.76658198818 91079.58341245934 81217.44397752779 1.0824256983085505 1.1130670092709134 0.9900993231825435 1.0712789274673455 1.083448673252936 0.9502078750201086 0.9336823148737533 0.9515045388940163 1.121428832919937 1.0 16.30950200396792 -6.753885298634028 24.997415160616818 0.9847285942470769 1.0664113504311283 0.3088234545773707 0.05691407497424779 213.92963843410467 707918.7778795839 0.019397642299666173 0.019038557527801016 1.762441462755898e-07 6.753885298634028 0.08168275618405141 GIAYIEFK ddPTM_PC-9_Lapatinib_30min_R1 2 GIAYIEFK 8 0 P19338;H7BY16 P19338 NCL Nucleolin 0 ; 138.9 0.013175999999999998 32348000.0 135876.0 132044.0 155895.0 133294.0 132421.0 112606.0 128886.0 112579.0 122533.0 129360.0 False True 133938.38332339353 131738.2602307593 143077.91487210285 143096.88541574913 124632.25712970292 107790.10387740686 135559.0864359587 117809.83132984514 108732.04321030727 151719.7036386346 0.8828015090406943 0.8683002739349728 0.9430410911748501 0.9431661279577552 0.8214638846550317 0.7104555393420813 0.8934837281176928 0.7764965822135017 0.716663957301715 1.0 17.211048933099015 -6.352682222328124 6.095555163217696 0.8058058892372305 0.9085077528365798 0.21119656432669942 0.08250407965779383 0.32302166129477705 17.660678877052536 0.02482375231230905 0.028208419936356324 4.439333556529592e-07 6.352682222328124 0.1027018635993493 GICFIR ddPTM_PC-9_Lapatinib_30min_R1 1 GICFIR 6 0 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 142.14 0.0076337 20410000.0 89479.0 85373.0 82442.0 82378.0 84877.0 85713.0 79677.0 76937.0 80495.0 63106.0 False True 88203.01305156099 85175.32406380157 75663.93699532312 88436.35292495207 79884.7017346025 82047.25479676202 83802.2851974448 80511.77389232712 71428.80545007203 74013.7880165405 1.191710563872903 1.1508034698179035 1.0222951563891562 1.1948632179883623 1.079321892249995 1.1085401382027118 1.1322523470723695 1.087794261716945 0.9650743106691043 1.0 16.175506434752414 -8.140080177451447 3.7402544600243495 0.9827820024868369 1.122356614660916 0.5698524526948671 0.04884699734644713 0.17279527369169828 4.114608403744929 0.037121093891916535 0.01246649124782491 7.243022303818504e-09 8.140080177451447 0.13957461217407918 GIDPFSLDALSK ddPTM_PC-9_Lapatinib_30min_R1 1 GIDPFSLDALSK 12 0 P40227-2;P40227 P40227-2 CCT6A T-complex protein 1 subunit zeta 0 96.171 0.020121 4030500.0 28919.0 27560.0 30853.0 29153.0 24067.0 29804.0 27157.0 25245.0 27411.0 28350.0 False True 28506.609756904898 27496.186513281344 28316.385436024117 31297.008871557104 22651.426377542524 28529.35239651736 28563.056579778477 26417.974861403505 24323.68452937354 33250.25972599951 0.8573349499166351 0.8269465183088822 0.8516139623980913 0.9412560722671561 0.6812405847113009 0.8580189337351036 0.8590325854641084 0.7945193535058733 0.7315336701070645 1.0 15.021077989454946 GIDT(ph)VEKS(ph)VGLT(ph)PKLT(ph)GRAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GIDTVEKSVGLTPKLTGRAK 20 3 C9JG08;Q68DN1 C9JG08 C2orf16 Uncharacterized protein C2orf16 4 GIDT(1)VEKS(1)VGLT(1)PKLT(1)GRAK 50.831 0.016697 8706100.0 7576.5 10279.0 33717.0 20896.0 30100.0 33658.0 18722.0 14987.0 33985.0 12045.0 True False 8859.051807303915 11299.431188455594 34520.941152434585 19725.264865746063 24202.121074657945 31892.915228477363 16948.516624457945 14593.607130039089 34481.96633169668 14228.663151832468 0.6226201093363422 0.7941316108112639 2.4261549229232218 1.386304859090413 1.7009413193916973 2.2414554964265894 1.1911531282736982 1.0256485078262338 2.42341574635252 1.0 13.796512499964631 -5.102051342060761 8.192159346162033 1.668241312838386 0.6651031104554392 0.36282029858064113 0.5141292817179778 0.2788508450022223 19.75621054467394 0.12646658233002278 0.33855911927828564 7.90585159921404e-06 5.102051342060761 -1.0031382023829467 GIEEEEILPGFILCDPNNLCHSGR ddPTM_PC-9_Lapatinib_30min_R1 2 GIEEEEILPGFILCDPNNLCHSGR 24 0 H3BR35;P15170;P15170-2;P15170-3 H3BR35 GSPT1 Eukaryotic peptide chain release factor GTP-binding subunit ERF3A 0 ; 152.63 6.1084e-07 3784200.0 16637.8 16111.5 17369.6 19502.9 20184.9 18587.9 16885.5 15344.8 19161.0 18896.5 False True 16400.54192100115 16074.194811637613 15941.538536594955 20937.20832576719 18997.663867040275 17792.93884751124 17759.748568613963 16057.775426946506 17002.886405724952 22162.734846996478 0.740005330308943 0.7252802924642673 0.7192947371635127 0.9447032809944315 0.8571895119529828 0.8028313730388992 0.8013338015917646 0.7245394369333745 0.7671835864619931 1.0 14.435848298244855 -11.914402918397437 2.189864641302181 2.5203180299381596 0.7888898938749611 0.47466122463312554 0.06721858499424113 4129028.6546503305 535028.9000657925 30952789.79072073 0.018832344344808818 1.2178592010223385e-12 11.914402918397437 -1.7314281360631985 GIERINAS(ph)KWRT(ph)LTSK ddPTM_PC-9_AZD4547_30min_R2 1 GIERINASKWRTLTSK 16 3 P0DPQ4;B9A014 P0DPQ4 C21orf140 Uncharacterized protein C21orf140 2 GIERINAS(0.308)KWRT(0.692)LT(0.5)S(0.5)K 46.3 0.044747 13922000.0 11617.0 4627.6 105830.0 218100.0 149830.0 60718.0 20266.0 87106.0 19674.0 37573.0 True False 15310.964351389142 6123.381202349781 104426.62505190645 167820.41461140977 129028.69075405653 56921.29386151775 22069.63473955586 73645.7691967516 20713.92747473296 36257.58070633112 0.4222831212981515 0.16888554291435517 2.880132182500306 4.62856074073651 3.5586679596503297 1.5699142842031495 0.6086902189726676 2.031182659241573 0.5712992171900756 1.0 15.145995043753928 -6.98877123443598 24.1916465199776 1.1316643334032748 2.3890877124921395 0.17724855347104296 1.2975314927645905 308.7182792773039 665108.8016887682 0.5235726074720589 0.4613019590369139 1.0261923329546293e-07 6.98877123443598 1.2574233790888647 GIFPVLCK ddPTM_PC-9_Lapatinib_30min_R1 1 GIFPVLCK 8 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 146.21 0.0059365 10025000.0 98102.0 88977.0 84335.0 79675.0 82784.0 79817.0 98308.0 87262.0 79592.0 88058.0 False True 96703.04749029638 88770.97922323075 77401.30184251428 85534.5652880084 77914.80787960609 76403.41297251458 103397.90721526182 91316.51108559291 70627.51081908363 103278.70797009034 0.936330918453218 0.859528367153266 0.7494410354642489 0.8281916666964824 0.7544130771094689 0.7397789387009093 1.001154151204196 0.8841755757831352 0.6838535474275826 1.0 16.656183332007075 -7.233183308813133 24.91985338912335 0.8826438670477327 0.8088466547504466 0.1356219347673565 0.09889115119151747 1625.0543539541509 1433184.6245650935 0.03836491354708105 0.029711221717771897 5.8454330560873865e-08 7.233183308813133 -0.07379721229728609 GIGLDESELDS(ph)EAELMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GIGLDESELDSEAELMR 17 0 Q96RS0 Q96RS0 TGS1 Trimethylguanosine synthase 1 GIGLDES(0.001)ELDS(0.999)EAELMR 89.46600000000001 0.015944 0.0 2479.6 2383.8 2517.4 3228.8 3389.8 2869.1 2515.0 4413.9 2636.2 1016.1 True False 2899.3473056676276 2620.4479100146355 2577.4243632926646 3047.9008039108357 2725.5930238829073 2718.6393452381103 2276.760992976806 4298.039801913627 2674.74943779958 1200.3108865568263 2.415496966777168 2.183141000688221 2.147297331182409 2.539259485227154 2.2707392346506636 2.2649460033114526 1.8968094170234933 3.5807721566558874 2.228380553534994 1.0 10.22919240416675 GIGT(ph)PPNTTPIK ddPTM_PC-9_AZD4547_30min_R2 2 GIGTPPNTTPIK 12 0 O96028;O96028-3;O96028-6;D6RIS1;D6R9V2;O96028-7;O96028-5 O96028;O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 GIGT(0.996)PPNT(0.002)T(0.003)PIK;GIGT(0.984)PPNT(0.013)T(0.003)PIK 107.37 0.0038131999999999997 21281000.0 80364.0 80564.0 88220.0 100998.0 88539.0 94415.0 79405.0 99433.0 80666.0 70395.0 True False 105918.08032495782 106604.73748511272 87050.14515807597 77714.47150354506 76246.8881443867 88511.21512459552 86471.89117213228 84067.9145930313 84929.84007709708 67930.49247657045 1.5592126078209938 1.569320839560838 1.2814590618211694 1.1440292668325518 1.1224250754649632 1.3029673699940194 1.2729466255813888 1.2375578555098319 1.2502461999136807 1.0 16.051771692898548 -5.328909638778072 3.603179490887046 1.205697031379799 1.570598939945931 0.7520168821015553 0.08425889197814315 0.10958908775453398 2.7821322544381966 0.022470717133599973 0.05465633075850612 4.689109356699067e-06 5.328909638778072 0.364901908566132 GIGT(ph)PPNTTPIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GIGTPPNTTPIK 12 0 O96028;O96028-3;O96028-6;D6RIS1;D6R9V2;O96028-7;O96028-5 O96028;O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 GIGT(0.94)PPNT(0.048)T(0.011)PIK;GIGT(0.987)PPNT(0.011)T(0.002)PIK;GIGT(0.869)PPNT(0.111)T(0.02)PIK 111.79 0.00252 21691200.0 182232.0 217397.0 231574.0 199004.0 228178.0 166636.0 197127.0 167339.0 164340.0 135927.0 True False 213080.27835393755 238978.73743327905 237095.6024092853 187854.4510596727 183468.15888947857 157897.3148140872 178453.70348411074 162946.52856032603 166743.16159926524 160569.48910245966 1.3270284382481323 1.4883197223152795 1.476591871435763 1.1699261927638223 1.1426090966286082 0.9833581441697972 1.1113799046233444 1.0148038053253665 1.0384486027284183 1.0 17.292838257065505 -5.969318295753796 2.2287639138674327 1.046052180310831 1.4393719931352182 0.8750969514200893 0.06410605332597319 0.09511674755645094 0.9529162601474468 0.019671562120447652 0.031283565238790424 1.07320257059142e-06 5.969318295753796 0.3933198128243873 GIGT(ph)PQPDVAK ddPTM_PC-9_AZD4547_30min_R2 2 GIGTPQPDVAK 11 0 H0YKA3;Q9Y6X8 H0YKA3 ZHX2 Zinc fingers and homeoboxes protein 2 1 GIGT(1)PQPDVAK;GIGT(1)PQPDVAK 130.15 0.00064185 0.0 49132.0 42781.0 58513.0 76916.0 69104.0 63381.0 49269.0 68662.0 51957.0 54145.0 True False 64754.953990914284 56609.121621947874 57737.079388284976 59184.20454035404 59510.102421867035 59417.77605054281 53653.84555329999 58051.86559579536 54703.34094768225 52249.40003045538 1.2393434939572436 1.0834406058050672 1.1050285621391043 1.132725055328032 1.1389624069784439 1.1371953747968224 1.026879648800292 1.111053247730267 1.0469659157004005 1.0 15.673126850655768 -1.5228787575873424 0.05191664979400077 0.7920071888327772 1.6904224595875785 0.5526017599323649 0.043308695777978024 372.64574770499905 1.46323373317106 5.802169797495446 26.497455410399258 0.029999999149862237 1.5228787575873424 0.8984152707548013 GIGTPPNTT(ph)PIK ddPTM_PC-9_Lapatinib_30min_R1 2 GIGTPPNTTPIK 12 0 O96028;O96028-3;O96028-6;D6RIS1;D6R9V2;O96028-7;O96028-5 O96028;O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 GIGTPPNT(0.041)T(0.959)PIK;GIGTPPNT(0.076)T(0.924)PIK 122.46 0.0009776 9311300.0 47346.0 68239.0 73081.0 71740.0 113019.0 110854.0 117870.0 117940.0 115822.0 111417.0 True False 46670.837357806966 68080.99678809181 67072.56228081787 77015.99891762434 106371.44462390308 106113.03283329542 123972.73185766052 123419.92296113828 102776.90670027018 130675.2799961794 0.35715123288177764 0.5209936936051128 0.5132765912786175 0.589369304736719 0.8140135198257322 0.8120360089253139 0.9487083697948469 0.9444779683253539 0.7865061142648794 1.0 16.99562672498135 -6.131398910619029 0.9318264568028888 0.9209197187504446 0.4111988509486259 0.9020595823535533 0.06513233164055288 0.17089315776759328 0.3093461046423186 0.029551923140970476 0.05554216938280528 7.389262405491041e-07 6.131398910619029 -0.5097208678018188 down GIGTPPNTT(ph)PIKNGSPEIK ddPTM_PC-9_AZD4547_30min_R2 1 GIGTPPNTTPIKNGSPEIK 19 1 O96028;O96028-3;O96028-6;D6RIS1;D6R9V2;O96028-7;O96028-5 O96028;O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 GIGT(0.001)PPNT(0.145)T(0.853)PIKNGS(0.001)PEIK 91.65700000000001 0.00066651 28476000.0 95929.0 46901.0 79674.0 128410.0 114850.0 90403.0 80473.0 88418.0 78947.0 101690.0 True False 126432.42655284546 62060.831050956695 78617.47070193311 98807.0584147232 98905.05995530549 84750.08611882465 87634.94110314202 74755.02974351235 83119.97724650525 98129.86405202695 1.2884194610298545 0.6324357182238934 0.8011574403104373 1.0069010017412967 1.0078996940510132 0.8636523339509719 0.8930506726951064 0.7617969357817349 0.8470405828997818 1.0 16.58240464099974 -6.9553254265448325 24.973450457213442 0.8588686172596512 0.9261243725903356 0.03665079961843409 0.1664298205993982 547.5424048167479 306078.91167270666 0.05833613497094767 0.051447605195327505 1.1083439971406818e-07 6.9553254265448325 0.0672557553306844 GIGTPPNTT(ph)PIKNGSPEIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GIGTPPNTTPIKNGSPEIK 19 1 O96028;O96028-3;O96028-6;D6RIS1;D6R9V2;O96028-7;O96028-5 O96028;O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 GIGT(0.002)PPNT(0.159)T(0.784)PIKNGS(0.055)PEIK;GIGT(0.001)PPNT(0.205)T(0.793)PIKNGS(0.001)PEIK 104.94 0.00018003 47169000.0 164788.0 100551.0 130673.0 196087.0 184030.0 232860.0 217611.0 247320.0 217090.0 188069.0 True False 192683.3536886422 110533.03876159132 133788.7399001123 185100.88111263182 147970.6425704084 220648.4116733979 196997.3107127932 240828.11205720084 220264.5305560699 222164.42094661493 0.8673006814846519 0.49752808433782425 0.6022059667792671 0.8331706774826501 0.6660411326886814 0.9931761833566441 0.8867185387894794 1.0840084610805918 0.9914482688881961 1.0 17.761268265809093 -6.7647139008483474 1.1771245759954927 1.0186371215074004 0.6587022538032629 0.6123271852604518 0.1145650023451226 0.295104904720424 0.8645131279557788 0.05720126743809145 0.051420828205878774 1.7190404624608235e-07 6.7647139008483474 -0.3599348677041375 GIGTPPNTTPIKNGS(ph)PEIK ddPTM_PC-9_AZD4547_30min_R2 1 GIGTPPNTTPIKNGSPEIK 19 1 O96028;O96028-3;O96028-6;D6RIS1;D6R9V2;O96028-7;O96028-5 O96028;O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 GIGTPPNT(0.005)T(0.004)PIKNGS(0.991)PEIK 83.25200000000001 0.00075349 33745000.0 53949.0 33402.0 49075.0 66677.0 62457.0 56649.0 51650.0 53436.0 41177.0 66179.0 True False 71103.65979108999 44198.54328828929 48424.23343496465 51305.64779938092 53785.923636295294 53106.72907475739 56246.7499406918 45178.694037122754 43353.532155488414 63862.09335331981 1.1133938156036618 0.692093556090605 0.7582625449976321 0.8033818671669622 0.842219864900487 0.8315845329551305 0.8807533074355112 0.7074414831216018 0.6788617453492028 1.0 15.962672223734545 -7.752629375271381 24.990074046796266 0.7698637030028812 0.8343311791155565 0.014040973343101837 0.13123155264554726 647.3611772994831 1836290.8310507808 0.06044147410471789 0.03421736685564343 1.7675455917589965e-08 7.752629375271381 0.06446747611267534 GIGTPPNTTPIKNGS(ph)PEIK ddPTM_PC-9_Lapatinib_30min_R1 2 GIGTPPNTTPIKNGSPEIK 19 1 O96028;O96028-3;O96028-6;D6RIS1;D6R9V2;O96028-7;O96028-5 O96028;O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 GIGTPPNT(0.004)T(0.004)PIKNGS(0.992)PEIK;GIGTPPNT(0.013)T(0.013)PIKNGS(0.973)PEIK 72.92699999999999 0.002479 47864000.0 310310.0 128551.0 142398.0 134331.0 141629.0 152062.0 105851.0 107553.0 152105.0 114524.0 True False 305884.9224961151 128253.34805764988 130690.58611217553 144210.1498550793 133298.6606733274 145558.66273383508 111331.44684707925 112550.30502153035 134973.3331633417 134319.32080636203 2.277296524876612 0.9548391645200693 0.9729842685891945 1.0736366815238452 0.9924012411103088 1.0836762861813154 0.8288565351486354 0.8379308676209403 1.0048690862420495 1.0 17.03530731476952 -4.761038853896013 24.999999513296544 0.9699082998031421 2.2772979939919944 0.9599945661924795 0.07992912891369296 1.8050901356236253 112533.399539392 0.02144478154382955 0.12229361414434983 1.7336488909550758e-05 4.761038853896013 1.3073896941888523 GIIDLTNMPPTILVPHPGGT(ph)STPPMDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GIIDLTNMPPTILVPHPGGTSTPPMDR 27 0 O75376-2;O75376;A0A088AWL3;E7EVK1 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 GIIDLTNMPPT(0.001)ILVPHPGGT(0.333)S(0.333)T(0.333)PPMDR 69.152 0.00030577 3770300.0 8150.5 6057.2 9716.7 10291.0 13073.0 10611.0 12013.0 9391.7 10061.0 7717.4 True False 9530.218670287148 6658.518785359785 9948.38297878996 9714.428633872158 10511.439495315723 10054.540480402075 10875.041673411679 9145.177826328696 10208.123091458001 9116.503529095211 1.045380900678815 0.7303807610131673 1.0912498357555411 1.0655871083544997 1.1530121676329737 1.1028943770287731 1.1928961184190972 1.0031453174061713 1.1197410343646441 1.0 13.154264895406877 -5.35116734866192 10.360556092722518 1.0967901871066608 0.8880928103341793 0.4460995745751687 0.09039075555604881 0.37253989371653207 41.0768766301362 0.021878845321585485 0.04558997659538645 4.4548455473645565e-06 5.35116734866192 -0.20869737677248146 GIITDS(ph)FGR ddPTM_PC-9_AZD4547_30min_R2 3 GIITDSFGR 9 0 A0A0A0MT72;Q9BSQ5-4;Q9BSQ5;Q9BSQ5-2;C9JUH3;Q9BSQ5-3 A0A0A0MT72 CCM2 Cerebral cavernous malformations 2 protein 1 GIIT(0.001)DS(0.999)FGR;GIIT(0.006)DS(0.994)FGR;GIIT(0.057)DS(0.943)FGR 97.59700000000001 0.004732500000000001 29599000.0 46388.0 53005.0 63502.0 92435.0 96191.0 84860.0 56721.0 83938.0 65436.0 68654.0 True False 61138.419069659925 70137.82968073087 62659.9219885303 71125.53885651396 82836.54002752101 79553.69078507836 61769.059116863114 70967.31080335373 68894.81336975821 66250.44435665112 0.9228378717058676 1.0586771207624281 0.9458037994614544 1.0735858385132993 1.250354481874577 1.200802372838601 0.9323569029112768 1.071197506560257 1.0399147362525065 1.0 16.01564251062566 -5.855654196362283 6.552781357174282 1.0909872799514941 0.9845838891354376 0.21060798105532097 0.09208966510550343 0.3538958063583173 20.60898956793557 0.027813787838800196 0.04168897948118565 1.3942665350733664e-06 5.855654196362283 -0.10640339081605654 GIITDS(ph)FGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GIITDSFGR 9 0 A0A0A0MT72;Q9BSQ5-4;Q9BSQ5;Q9BSQ5-2;C9JUH3;Q9BSQ5-3 A0A0A0MT72 CCM2 Cerebral cavernous malformations 2 protein 1 GIIT(0.318)DS(0.682)FGR;GIIT(0.044)DS(0.956)FGR;GIIT(0.011)DS(0.989)FGR 88.134 0.010353 19798200.0 37622.7 39691.5 49447.5 49438.7 56479.0 50317.0 49850.0 43559.9 46633.0 35141.0 True False 43991.48002780347 43631.8098080149 50626.515930688045 46668.80992142797 45412.34538789387 47678.287941983916 45127.84711725399 42416.49878052909 47314.919404031556 41511.78512399705 1.0597347210292087 1.0510704292211301 1.2195697144669881 1.1242303789641117 1.0939627205201057 1.148548244783194 1.0871092867352161 1.0217941399973436 1.1397948621746898 1.0 15.341233352786142 -7.521377833781418 24.725760991015513 1.059367034208379 1.1173266439615974 0.1989357526922073 0.05579738929383292 89.84922120753978 1480255.15375896 0.025993474466516914 0.01529302866371861 3.010385865646253e-08 7.521377833781418 0.057959609753218455 GIITDS(ph)FGR ddPTM_PC-9_Lapatinib_30min_R1 4 GIITDSFGR 9 0 A0A0A0MT72;Q9BSQ5-4;Q9BSQ5;Q9BSQ5-2;C9JUH3;Q9BSQ5-3 A0A0A0MT72 CCM2 Cerebral cavernous malformations 2 protein 1 GIIT(0.01)DS(0.99)FGR;GIIT(0.001)DS(0.999)FGR;GIIT(0.077)DS(0.923)FGR;GIIT(0.002)DS(0.998)FGR 97.59700000000001 0.004732500000000001 43184000.0 147791.0 112920.0 111197.0 107936.0 93455.0 105584.0 96738.0 79151.0 120637.0 66716.0 True False 145683.47323845018 112658.54067778403 102054.81189283288 115873.97350394075 87958.16063959942 101068.4184483253 101746.62029733066 82828.64441493146 107049.59069607226 78247.77170651783 1.8618226444180663 1.4397667591139836 1.3042519891251037 1.4808597226071392 1.1240979611470872 1.291645963125958 1.3003133262241569 1.058543171371001 1.3680848458864845 1.0 16.255762047968766 -1.522878745281785 0.58168725317109 1.2031844336225883 35.842243524123525 0.6937008172566268 0.12939141674209084 86.59737902184145 0.7147683674251953 0.057219502089778114 3790.6332255533966 0.02999999999990002 1.522878745281785 34.639059090500936 GIKADY(ph)KQY(ph)WDVELGVT(ph)YIPWDK ddPTM_PC-9_Lapatinib_30min_R1 1 GIKADYKQYWDVELGVTYIPWDK 23 2 O95104-2;O95104-3;O95104 O95104-2 SCAF4 Splicing factor, arginine/serine-rich 15 3 GIKADY(0.999)KQY(0.999)WDVELGVT(0.843)Y(0.159)IPWDK 43.11600000000001 0.018706999999999998 24755000.0 25275.0 58572.0 21097.0 41277.0 44612.0 33236.0 53540.0 46083.0 16840.0 45431.0 True False 24914.57386513268 58436.380132652936 19362.486096775046 44312.64827603547 41988.00987056662 31814.573756900125 56312.03922676805 48224.18441426253 14943.301866938478 53283.687816997684 0.4675835116875083 1.0967029972353288 0.3633848723698577 0.8316362866666969 0.788008705680696 0.5970790510252776 1.0568344935165 0.9050459228702042 0.28044796595650634 1.0 15.70140631577197 GILAADES(ph)TGSIAK ddPTM_PC-9_AZD4547_30min_R2 3 GILAADESTGSIAK 14 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 GILAADES(0.92)T(0.074)GS(0.006)IAK;GILAADES(0.815)T(0.185)GSIAK;GILAADES(0.932)T(0.045)GS(0.023)IAK 216.27 2.0815999999999997e-15 35059700.0 127952.0 164920.0 170981.0 216083.0 204372.0 181648.0 169664.0 209449.0 157157.0 186303.0 True False 168638.0744330676 218227.16481362376 168713.68022299922 166268.40279907043 175998.47551750712 170289.52184454325 184763.76731728035 177083.46970920922 165463.99817762565 179780.5886762195 0.9380215944046146 1.2138527658658724 0.9384421391947297 0.9248406851004133 0.9789626166731278 0.9472074994215899 1.0277181128271609 0.9849977186810324 0.9203663164971738 1.0 17.455877732595276 GILAADES(ph)TGSIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GILAADESTGSIAK 14 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 GILAADES(0.736)T(0.103)GS(0.161)IAK;GILAADES(0.865)T(0.131)GS(0.004)IAK;GILAADES(0.985)T(0.005)GS(0.01)IAK;GILAADES(0.935)T(0.064)GS(0.001)IAK;GILAADES(0.977)T(0.021)GS(0.001)IAK 205.96 8.9505e-11 25671400.0 175475.2 212900.4 168932.4 210688.9 207628.0 171396.3 193568.0 160702.1 155711.2 151172.2 True False 205179.68556682073 234035.7447022732 172960.3890956947 198884.68399563016 166944.78387006905 162407.97630205797 175231.83772903954 156483.84015294994 157988.18172335104 178578.52318152323 1.1489605911807081 1.3105481024970638 0.9685396990313457 1.1137099828822412 0.9348536481084648 0.9094485350680829 0.9812593060304244 0.8762746906238312 0.8846986687349726 1.0 17.44619905902463 -5.6132542353479975 0.9424056082516269 0.9213783075524168 1.2505847833561525 0.6361914288392335 0.07917344625309988 0.45892866230435436 0.696185609664911 0.029723783367893313 0.11923395255959511 2.4363841451447025e-06 5.6132542353479975 0.32920647580373574 GILAADES(ph)TGSIAK ddPTM_PC-9_Lapatinib_30min_R1 4 GILAADESTGSIAK 14 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 GILAADES(0.77)T(0.226)GS(0.004)IAK;GILAADES(0.959)T(0.04)GS(0.001)IAK;GILAADES(0.775)T(0.217)GS(0.008)IAK;GILAADES(0.911)T(0.051)GS(0.038)IAK 178.68 7.041899999999999e-05 33941600.0 158361.0 180611.0 190057.0 165958.0 176032.0 195626.0 190092.0 190019.0 177964.0 146693.0 True False 156102.74310014918 180192.8063262066 174431.2471012361 178163.10493965837 165678.14385222786 187259.5320064794 199934.03363270054 198847.97643846425 157919.82027599975 172048.6895938643 0.9073172453021473 1.0473361160237091 1.0138481584079253 1.0355388661211409 0.9629724250927184 1.0884101032592668 1.1620782123052606 1.1557657132284003 0.9178786577728841 1.0 17.392457378289485 -6.774574665109764 24.976495367542 1.0806401430217951 0.9998756429456234 0.16071124135176484 0.07679779952652385 377.56096701958955 717920.8102986449 0.026852663896640212 0.0238223181928659 1.6804489934288044e-07 6.774574665109764 -0.08076450007617175 GILAADEST(ph)GSIAK ddPTM_PC-9_AZD4547_30min_R2 1 GILAADESTGSIAK 14 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 GILAADES(0.344)T(0.642)GS(0.014)IAK 89.46 0.012996 5975400.0 26311.0 23504.0 32287.0 37000.0 31735.0 38044.0 32478.0 34965.0 32385.0 32256.0 True False 34677.350697202324 31101.208354228842 31858.853284048957 28470.221644301535 27329.143035974055 35665.102665891216 35368.47908177713 29561.962665768326 34096.80498471215 31126.727257962273 1.1140699248531436 0.9991801610390343 1.0235208160504379 0.9146551581974877 0.877996032460599 1.1458031668513438 1.1362736206945692 0.9497292285428537 1.0954188887940388 1.0 14.925866275761681 -6.773653476827735 24.999991912993 1.0667298196470434 0.9847567824240206 0.19613322799705712 0.08049764630886279 404.48998540330757 827911.4855411571 0.029647042909916325 0.02633807177000094 1.6840172009477512e-07 6.773653476827735 -0.08197303722302274 GILAADEST(ph)GSIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GILAADESTGSIAK 14 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 GILAADES(0.225)T(0.751)GS(0.024)IAK;GILAADES(0.272)T(0.672)GS(0.057)IAK 185.95 1.3341e-05 11488800.0 70243.0 99940.0 73229.0 84414.0 92826.0 77797.0 83789.0 73084.0 64470.0 66620.0 True False 82133.75253751062 109861.38271954979 74975.05708252912 79684.55725388057 74637.41165701639 73717.1883662087 75851.89934017244 71165.6224388989 65412.751784742824 78697.6786363702 1.043661693212288 1.3959926725053013 0.9526971872824637 1.0125401236047933 0.9484067757816004 0.9367136317555909 0.9638390948054906 0.9042912532112435 0.8311903593368797 1.0 16.264033460400512 -5.333294029421797 10.053743646118637 0.9431303749030948 1.2195420822584209 0.5901004710278148 0.09205385976986542 0.31049947436492575 42.22263791745641 0.022679848017054697 0.04728539773899437 4.6420089191995995e-06 5.333294029421797 0.27641170735532605 GILAADEST(ph)GSIAK ddPTM_PC-9_Lapatinib_30min_R1 2 GILAADESTGSIAK 14 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 GILAADES(0.161)T(0.532)GS(0.307)IAK;GILAADES(0.099)T(0.529)GS(0.372)IAK 196.37 2.778e-07 32896900.0 121454.0 122865.0 114206.0 100343.0 123166.0 125333.0 124361.0 131427.0 114717.0 92448.0 True False 119722.04368806432 122580.51364130297 104816.42352790883 107722.5589544351 115921.61803367265 119972.79975549282 130799.80407695356 137533.57821785228 101796.36343643586 108427.51362078339 1.1041666426732117 1.1305296003560368 0.9666958138918129 0.9934983783837946 1.0691162617552894 1.106479303538105 1.2063340724976457 1.2684379971938216 0.9388425505398985 1.0 16.72637136330261 -6.760055077319843 3.569567298595976 1.1288162035811773 1.0475046298881951 0.039015927404082884 0.099027838100311 0.5173805479678452 14.033710614458432 0.03595962536249498 0.0335727008934272 1.7375804544477993e-07 6.760055077319843 -0.08131157369298214 GILAADEST(ph)GSIAKR ddPTM_PC-9_AZD4547_30min_R2 1 GILAADESTGSIAKR 15 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 GILAADES(0.024)T(0.535)GS(0.441)IAKR 65.949 0.027901 16078000.0 30894.0 27548.0 43084.0 54172.0 46382.0 40882.0 32741.0 41734.0 32051.0 38900.0 True False 40717.64936488045 36452.35226949864 42512.67800941446 41683.48234905685 39942.65991159755 38325.642077251694 35654.885572278654 35284.969251914066 33745.15042658665 37538.12284023848 1.0847012659150266 0.9710755229993556 1.1325200833922249 1.1104306554289074 1.0640558687921804 1.0209791853568406 0.9498313414345505 0.9399769243146816 0.8989567904129185 1.0 15.196068887022681 -7.092701055776998 2.200064614878937 0.9394904570341553 1.0726629851300786 0.625524581417177 0.04565591189050128 0.21180968300445357 2.0211984475924747 0.021078671857415562 0.015514930184636615 8.07790877336616e-08 7.092701055776998 0.13317252809592328 GILAADESTGS(ph)IAK ddPTM_PC-9_AZD4547_30min_R2 2 GILAADESTGSIAK 14 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 GILAADES(0.034)T(0.137)GS(0.83)IAK;GILAADES(0.129)T(0.277)GS(0.594)IAK 204.17 1.1256000000000001e-10 62935000.0 196961.0 221120.0 232510.0 265800.0 227110.0 251880.0 256380.0 246870.0 233040.0 213340.0 True False 259590.50095669797 292592.7157627245 229426.7654806648 204523.91656906356 195579.69670395658 236129.9037820601 279197.3233261288 208721.9140082428 245358.0186394105 205871.03153564184 1.2609374860578957 1.4212427731099642 1.1144198567875967 0.993456510337905 0.9500107676397223 1.1469797475667656 1.3561758604089582 1.013847904930264 1.1918044846291664 1.0 17.651381314605658 -5.295668414186646 10.767532555359418 1.0985184348092063 1.3410243001073632 0.4063667663921655 0.11853529772009476 0.7397025240703226 231.70152376428646 0.03246540264221888 0.06811420621889105 5.062110089045402e-06 5.295668414186646 0.24250586529815688 GILAADESTGS(ph)IAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GILAADESTGSIAK 14 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 GILAADES(0.013)T(0.055)GS(0.931)IAK;GILAADES(0.089)T(0.244)GS(0.667)IAK;GILAADES(0.001)T(0.003)GS(0.996)IAK;GILAADES(0.062)T(0.039)GS(0.899)IAK 188.39 3.6404000000000003e-06 35162000.0 157323.0 193566.0 141474.0 150297.0 177194.0 145121.0 177209.0 127501.0 140486.0 126160.0 True False 183954.6766291133 212781.95324687185 144847.27670313293 141876.34635944825 142474.10769777198 137510.5992890801 160422.4806379431 124154.23384847655 142540.3419765997 149031.80931798948 1.2343316334341001 1.4277619940375184 0.9719218827577406 0.9519870087380231 0.9559979735183559 0.9226929466827679 1.076431141593734 0.8330720429191624 0.9564424040002164 1.0 17.18526076651667 -5.272446038019565 24.582140071046307 0.9552077395908133 1.3310468059824658 0.8111071004600863 0.07188556359120866 183.06764646363848 408861.64644261816 0.017753861399100495 0.037544125518735295 5.340156219888205e-06 5.272446038019565 0.37583906639165254 GILAADESTGS(ph)IAK ddPTM_PC-9_Lapatinib_30min_R1 2 GILAADESTGSIAK 14 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 GILAADES(0.06)T(0.119)GS(0.821)IAK;GILAADES(0.027)T(0.026)GS(0.948)IAK 194.67 1.4279000000000002e-07 33095100.0 116664.0 139757.0 128911.0 122113.0 129146.0 134911.0 135037.0 137539.0 122941.0 105649.0 True False 115000.34996644274 139433.4012531446 118312.43519085053 131093.5973770264 121549.88619080507 129141.17102290133 142028.55511888443 143929.5640508049 109094.08995387673 123910.28888155607 0.9280936313236248 1.125277025109891 0.9548233343555801 1.057971848506759 0.9809507127127493 1.0422150750237162 1.1462208376791643 1.1615626543198923 0.8804280172258986 1.0 16.918936460963806 -6.997229299143879 24.83592029682603 1.0653309336671704 1.0151293767048546 0.022788922456852267 0.08978259445062461 243.9858577309288 2186988.203694706 0.030768289103592226 0.02697998883878837 1.0064001685965805e-07 6.997229299143879 -0.05020155696231576 GILAADESTGS(ph)IAKR ddPTM_PC-9_AZD4547_30min_R2 1 GILAADESTGSIAKR 15 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 GILAADES(0.005)T(0.018)GS(0.977)IAKR 68.123 0.013035 52028000.0 39342.0 31624.0 50515.0 71277.0 46213.0 42363.0 50886.0 43002.0 43404.0 42452.0 True False 51851.93763556438 41845.839558974345 49845.138094085334 54845.18886867245 39797.122644445204 39714.03491313083 55414.75542075594 36357.02898765538 45698.24682897779 40965.76840138315 1.2657381921295456 1.0214830867803637 1.216750961576065 1.338805324760384 0.9714726269628939 0.9694444035325342 1.3527088001328673 0.8874977916056332 1.1155227550286804 1.0 15.32213125548617 -6.276431642678573 24.850924872775632 1.0549795108265487 1.1976119226411284 0.24116065636157658 0.13915286543957084 1251.2897443766662 2074111.1039572824 0.04309250293290522 0.049046414797671044 5.291372760950676e-07 6.276431642678573 0.14263241181457964 GILAADESTGS(ph)IAKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GILAADESTGSIAKR 15 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 GILAADES(0.001)T(0.048)GS(0.952)IAKR;GILAADES(0.076)T(0.206)GS(0.718)IAKR;GILAADES(0.018)T(0.059)GS(0.923)IAKR 118.52 0.00016401 54025500.0 114412.0 88591.0 111267.0 130329.0 127440.0 142881.0 127291.0 119088.0 113757.0 96372.0 True False 133779.69185999563 97385.72900247764 113920.02726244723 123027.0886623192 102469.04683569439 135388.06883237467 115233.0749729666 115962.06618416613 115420.48091789983 113843.48071966782 1.1751194799587992 0.8554352729453493 1.0006723840688594 1.0806687206381667 0.9000870861285221 1.1892474472539978 1.012206182071335 1.0186096336048895 1.0138523540238134 1.0 16.79669215192189 GILAADESTGS(ph)IAKR ddPTM_PC-9_Lapatinib_30min_R1 2 GILAADESTGSIAKR 15 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 GILAADES(0.002)T(0.106)GS(0.892)IAKR;GILAADES(0.065)T(0.05)GS(0.885)IAKR 90.706 0.0018959 72348000.0 136773.0 104333.0 121135.0 95467.0 102157.0 104478.0 92414.0 92643.0 110758.0 81029.0 True False 134822.5919389036 104091.4233487005 111175.74789462205 102487.96164857625 96148.32610838959 100009.71949011332 97198.74473482523 96947.53198989901 98283.26770655409 95034.75468564431 1.4186661751784324 1.095298490462924 1.1698430564941098 1.078426118819222 1.0117175177273698 1.0523488993150474 1.0227705122861521 1.0201271346528098 1.034182368667707 1.0 16.53616759028997 -1.522878745344713 0.7439794689221642 1.0293836075892584 62.84876303151206 0.8743800729910687 0.04234212537578376 115.88126369941332 0.5133545765139739 0.01538270524377584 11996.358334515662 0.0299999999955531 1.522878745344713 61.8193794239228 GILAADESTGSIAK ddPTM_PC-9_AZD4547_30min_R2 1 GILAADESTGSIAK 14 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 164.04 0.0024884 7106400.0 34311.0 23054.0 23627.0 33592.0 31580.0 28131.0 27764.0 36171.0 28450.0 30434.0 False True 45221.18428686519 30505.754654458462 23313.69054239244 25847.88339122642 27195.662110479298 26371.964122967776 30234.94221400518 30581.603076891355 29953.808918173865 29368.514923388662 1.5397845074846357 1.0387230928780848 0.7938328037086326 0.8801222485595122 0.9260142088022661 0.897967234358368 1.0295019102217697 1.041305736999885 1.0199293017134852 1.0 14.841982694349708 -2.151049361319937 7.990207049164467 1.0030279775623934 1.1490227029965172 0.0 0.19174981418045994 0.0 0.0 0.044824903491822665 0.0 0.007062372797327528 2.151049361319937 0.14599472543412384 GILAADESTGSIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GILAADESTGSIAK 14 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ;;; 182.35 7.8916e-27 27730300.0 127207.0 150720.0 152610.0 175842.0 167033.0 159581.0 184166.0 160207.0 159105.0 130204.0 False True 148740.63264722633 165682.48552622113 156248.80117664827 165990.14282745606 134304.0827064233 151212.29143370484 166720.46323362473 156001.73600334808 161431.6096279123 153808.95450570338 0.9670479402531202 1.077196617444516 1.0158628389275892 1.0791968735558954 0.8731876706270907 0.9831176079419859 1.0839451042978292 1.0142565269017767 1.04955924150649 1.0 17.23077997152663 -7.227504025971983 24.854941352176343 1.0381283117695153 1.0014669399872462 0.08969758541309691 0.058493232976272534 1658.8727919034416 1214994.3929974467 0.0231379119353954 0.01792141111004882 5.922375967234281e-08 7.227504025971983 -0.036661371782269025 GILAADESTGSIAK ddPTM_PC-9_Lapatinib_30min_R1 2 GILAADESTGSIAK 14 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ; 224.66 1.0365999999999999e-19 55318000.0 168817.0 183659.0 183517.0 153781.0 155758.0 169164.0 189096.0 169092.0 139529.0 159349.0 False True 166409.63862275373 183233.7488694757 168428.94065610587 165090.56773837778 146596.6206720102 161929.25006054438 198886.465626166 176948.63162069497 123813.77471449281 186892.2623308037 0.890404110621791 0.9804244787039266 0.9012087421681626 0.8833461892936134 0.7843910649041785 0.8664310016961847 1.0641770993928699 0.9467948507546649 0.6624874308350953 1.0 17.511847314637805 -5.503307100172352 20.774272869998608 0.8872781118316538 0.9367649454488745 0.03151311212796992 0.10637850191970184 358.85870080374843 380898.8486205788 0.028608117923571777 0.05778677084573987 3.138288748911634e-06 5.503307100172352 0.049486833617220616 GILAADESTGSIAKR ddPTM_PC-9_Lapatinib_30min_R1 1 GILAADESTGSIAKR 15 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 54.95 0.045761 5159200.0 35886.0 14081.0 17881.0 16211.0 17994.0 14529.0 12991.0 11384.0 17139.0 14137.0 False True 35374.259059313576 14048.396309634067 16410.893202656054 17403.211018310696 16935.628297565137 13907.628538753213 13663.610414548823 11912.942199335217 15208.62533832889 16580.561613631577 2.1334777363772113 0.8472810895672128 0.9897670287093273 1.0496152919212811 1.0214146355357254 0.8387911617733845 0.8240740412143455 0.718488461183431 0.9172563446720188 1.0 14.01720525390295 -4.759710669230894 24.99997334159636 0.908194148328414 2.1334792612223965 0.9309743564133823 0.09978735061720272 11.590567726613457 167569.42364198767 0.02774025111638234 0.172705215400315 1.7389589525412135e-05 4.759710669230894 1.2252851128939826 GILFVGSGVSGGEEGAR ddPTM_PC-9_Lapatinib_30min_R1 1 GILFVGSGVSGGEEGAR 17 0 P52209-2;P52209;K7EMN2;K7EM49;K7EPF6 P52209-2 PGD 6-phosphogluconate dehydrogenase, decarboxylating 0 187.62 1.0517000000000001e-07 18352000.0 46507.0 45186.0 41401.0 47784.0 33716.0 46198.0 39679.0 38519.0 41179.0 30127.0 False True 45843.80165166075 45081.37459321954 37997.16959248159 51298.19476275112 31732.891168206414 44222.21923279791 41733.38446916192 40308.73336052295 36540.987385906126 35334.41180829587 1.2974264832929092 1.2758490176037192 1.0753587691973565 1.4517913879836328 0.8980732816601215 1.2515340420189291 1.1810974722200893 1.140778388479052 1.0341473231295442 1.0 15.108786273034372 -1.5228787493065736 0.08815164328837369 0.8672935140695809 2.025366920707114 0.26364808651834026 0.1339990324094649 229.34003118539198 1.463144158494529 2.582952504765263 32.13851952388052 0.029999999721877467 1.5228787493065736 1.1580734066375333 GILHLS(ph)PDVYQEMEASR ddPTM_PC-9_AZD4547_30min_R2 2 GILHLSPDVYQEMEASR 17 0 H0YBY0;E7EPX0;E7EVJ4;Q9NUL3-4;Q9NUL3-6;Q9NUL3-8;Q9NUL3-3;Q9NUL3-7;Q9NUL3-2;Q9NUL3;E5RJ67;E5RJN7 H0YBY0 STAU2 Double-stranded RNA-binding protein Staufen homolog 2 1 GILHLS(1)PDVYQEMEASR;GILHLS(1)PDVYQEMEASR 98.76 0.00091824 13688400.0 43647.0 50766.0 61254.0 73631.0 67697.0 62444.0 48840.0 73313.0 53135.0 59700.0 True False 57525.838086001684 67175.11671676235 60441.73193734742 56656.51053760989 58298.44008527926 58539.36680866652 53186.66538438312 61984.160415143015 55943.60762274757 57609.92117126574 0.9985404756063788 1.1660338245744288 1.0491549147873875 0.9834505825685561 1.0119513948294887 1.0161334301194003 0.9232205894930331 1.0759285754075814 0.9710759272944591 1.0 15.814029663301294 -5.5562141039229935 5.730849129682091 0.9996008793516311 1.0884379882967767 0.30600273297933733 0.05224969957223169 0.17951386316489282 16.223989252428215 0.013332754571843625 0.02402718484729798 2.7783432276996263e-06 5.5562141039229935 0.08883710894514563 GILHLS(ph)PDVYQEMEASR ddPTM_PC-9_Lapatinib_30min_R1 2 GILHLSPDVYQEMEASR 17 0 H0YBY0;E7EPX0;E7EVJ4;Q9NUL3-4;Q9NUL3-6;Q9NUL3-8;Q9NUL3-3;Q9NUL3-7;Q9NUL3-2;Q9NUL3;E5RJ67;E5RJN7 H0YBY0 STAU2 Double-stranded RNA-binding protein Staufen homolog 2 1 GILHLS(1)PDVYQEMEASR;GILHLS(1)PDVYQEMEASR 62.69 0.019405000000000002 6903100.0 34946.0 33326.0 40832.0 31328.0 32077.0 30394.0 27822.0 30865.0 37723.0 26897.0 True False 34447.66363168847 33248.83569454335 37474.95057607806 33631.9656271444 30190.29392580845 29094.11947187453 29262.487025908467 32299.1005782222 33474.23849919952 31546.110612000306 1.0919781539910152 1.0539757532548344 1.187942026736646 1.0661208299431568 0.9570211141757649 0.9222727907638469 0.9276099797474514 1.02386950250328 1.0611209385180354 1.0 14.945174522739094 -6.109456425549566 4.514338897866604 0.9780607544962712 1.1085427671685755 0.576942539903766 0.05037395387850753 0.17350791489968218 5.728776137547886 0.01628630844452035 0.021554518937651247 7.772192963093343e-07 6.109456425549566 0.1304820126723043 GILHTDSQSQS(ph)LR ddPTM_PC-9_AZD4547_30min_R2 2 GILHTDSQSQSLR 13 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 GILHTDS(0.133)QS(0.133)QS(0.733)LR;GILHTDS(0.001)QS(0.039)QS(0.96)LR 120.54 0.00011957 38416000.0 67869.0 48963.0 94888.0 159522.0 118310.0 98439.0 83010.0 124616.0 92154.0 115232.0 True False 89449.93023710349 64789.332226349 93629.72312128227 122746.66749033166 101884.69867925307 92283.59376846999 90397.72918832205 105359.46059080199 97025.07230388037 111197.76275389113 0.8044220317190992 0.5826496021304334 0.8420108534783078 1.1038591465369783 0.9162477387674585 0.8299051301303336 0.8129455750687643 0.9474962263763275 0.8725451834729937 1.0 16.762768236452047 -5.51204019518356 24.878208818432423 0.9192869866331377 0.698234377512072 0.4919716672814328 0.09354385999463767 393.4492220224146 903100.1733678174 0.0253793932263118 0.048052391184491124 3.0758121264482456e-06 5.51204019518356 -0.22105260912106572 GILHTDSQSQS(ph)LR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GILHTDSQSQSLR 13 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 GILHTDSQS(0.006)QS(0.994)LR;GILHTDS(0.042)QS(0.219)QS(0.739)LR 137.39 2.7603000000000003e-05 11190000.0 55621.0 51449.0 78887.0 76494.0 94665.0 88661.0 87432.0 72417.0 74181.0 50574.0 True False 65036.53673517469 56556.516705404385 80767.96526061339 72208.28917689393 76116.07280838866 84011.4610812298 79149.80800713619 70516.13048215408 75265.75678833583 59742.66585643627 1.0886112262124321 0.9466687817599516 1.3519310546787726 1.2086552908504784 1.2740655562859928 1.4062221676399962 1.3248456002505138 1.180331166533593 1.259832578767109 1.0 15.866473995036284 -5.259150373114472 24.999819421376092 1.26470607379479 1.017639992665295 0.41214849416461574 0.11034812539306808 168.9474687502221 1845164.0183827674 0.02723844593444672 0.06531611966273508 5.506170139660662e-06 5.259150373114472 -0.2470660811294949 GILHTDSQSQS(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 2 GILHTDSQSQSLR 13 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 GILHTDSQS(0.006)QS(0.994)LR;GILHTDS(0.002)QS(0.191)QS(0.807)LR 130.02 4.8553999999999996e-05 36039000.0 132517.0 104394.0 155926.0 113372.0 146096.0 126610.0 118286.0 98073.0 153411.0 82649.0 True False 130627.28327935877 104152.28210694825 143106.36617176584 121709.75507790543 137502.92051578718 121195.18544232528 124410.27030215682 102629.8296130889 136132.2376905522 96934.76952712993 1.3475792423769992 1.0744574172407588 1.4763161543569099 1.2555840971370085 1.4185097998020524 1.2502756857373596 1.2834431949346832 1.0587514687840163 1.404369539997222 1.0 16.564726618224043 -7.557184129246919 23.180847482551634 1.1731553160502068 1.30111475663192 0.18202807557789602 0.14113762682153053 159.93759728279065 108069.64509600872 0.06255930711813709 0.03611903830285161 2.772144540309963e-08 7.557184129246919 0.12795944058171327 GILLEDGSES(ph)PAKR ddPTM_PC-9_AZD4547_30min_R2 2 GILLEDGSESPAKR 14 1 Q08999;Q08999-2 Q08999 RBL2 Retinoblastoma-like protein 2 1 GILLEDGS(0.059)ES(0.941)PAKR;GILLEDGS(0.065)ES(0.935)PAKR 90.259 0.0022929 36915000.0 57173.0 63289.0 82081.0 86461.0 78407.0 67998.0 69695.0 70520.0 67250.0 70901.0 True False 75352.82472772416 83745.9315661499 80992.5523092274 66528.7522591339 67521.54145333609 63746.07431067371 75897.71998289494 59622.75438838787 70804.69770640398 68418.77757058489 1.1013471360254237 1.2240196995591248 1.1837766646103935 0.9723756346055564 0.9868861130071616 0.9317043737723824 1.109311254568884 0.8714384633206502 1.034872299981648 1.0 16.06210470744056 -5.760871441474599 24.999890432745893 0.9841293448615056 1.175145059471286 0.6257991428557836 0.06480738733942344 8.716173088588631 383633.4111884313 0.016910340461800667 0.02716347310815986 1.734317309086013e-06 5.760871441474599 0.1910157146097804 GILLEDGSES(ph)PAKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GILLEDGSESPAKR 14 1 Q08999;Q08999-2 Q08999 RBL2 Retinoblastoma-like protein 2 1 GILLEDGS(0.004)ES(0.996)PAKR;GILLEDGS(0.16)ES(0.84)PAKR 86.777 0.0029195000000000002 26714000.0 50763.0 49817.0 49429.0 57208.0 63777.0 56708.0 66317.0 57920.0 56311.0 52641.0 True False 59356.17328504836 54762.50253091665 50607.574820526366 54002.82123083842 51280.354677025265 53734.13265127142 60034.97366649815 56399.66137131273 57134.44184505432 62184.3965940733 0.9545187625203314 0.8806470035947246 0.8138307612901995 0.8684304132330415 0.824649871764016 0.8641095772310307 0.9654346902872414 0.9069744897498626 0.9187906448303419 1.0 15.924265002021768 -7.248721716358679 23.87559040646225 0.9400478285611584 0.8639144106827756 0.45105665158349517 0.04283002082003773 421.30608347333003 790942.4060812952 0.016799993001052508 0.012912890738080766 5.639989346572839e-08 7.248721716358679 -0.07613341787838279 GILLEDGSES(ph)PAKR ddPTM_PC-9_Lapatinib_30min_R1 3 GILLEDGSESPAKR 14 1 Q08999;Q08999-2 Q08999 RBL2 Retinoblastoma-like protein 2 1 GILLEDGS(0.001)ES(0.999)PAKR;GILLEDGS(0.366)ES(0.634)PAKR;GILLEDGS(0.106)ES(0.894)PAKR 122.16 2.8333e-05 33173000.0 94378.0 84449.0 84786.0 75068.0 73374.0 84450.0 74449.0 75733.0 78881.0 61766.0 True False 93032.15241319452 84253.46352903097 77815.22236342462 80588.75113950706 69058.28557883439 80838.27036256505 78303.6049382453 79251.83165690927 69996.59112624545 72442.17080197846 1.2842264579218508 1.1630444338745567 1.0741702174570869 1.1124563254709385 0.9532884618767988 1.1159007173257884 1.080911906302327 1.0940013362319734 0.9662409388252868 1.0 16.144542158282654 -4.3671285228715115 0.9284137985853584 1.0471700607267258 1.6186582555731035 0.6636217118795951 0.05390368846586189 2.49380122558933 1.003541245662102 0.01781134542101046 1.7260356637595424 4.2940933077469394e-05 4.3671285228715115 0.5714881948463777 GILSLPHQAS(ph)PVSR ddPTM_PC-9_AZD4547_30min_R2 4 GILSLPHQASPVSR 14 0 O75925;O75925-2 O75925 PIAS1 E3 SUMO-protein ligase PIAS1 1 GILSLPHQAS(0.992)PVS(0.008)R;GILSLPHQAS(0.997)PVS(0.003)R;GILSLPHQAS(0.992)PVS(0.008)R;GILSLPHQAS(0.991)PVS(0.009)R 148.52 3.2191e-05 87434100.0 207798.0 201632.0 328746.0 468080.0 372581.0 285737.0 258598.0 388785.0 279489.0 332466.0 True False 273873.44153309445 266805.60087133566 324386.61324117973 360171.3877639096 320854.559366197 267869.8202198445 281612.7210292938 328707.2116405192 294262.21795189765 320826.4665347748 0.8536497767506003 0.8316196720086254 1.0110967986676966 1.12263614549665 1.000087563946097 0.8349367903249645 0.8777727226527597 1.0245638871096385 0.9172005699224387 1.0 18.291433636065896 -5.253716697473636 24.45722729166132 0.9723171626507146 0.842634701799925 0.31548896144061167 0.07710994453180774 581.2324649882345 1840709.3711912085 0.021974087269956654 0.05577615498048302 5.57549335470095e-06 5.253716697473636 -0.1296824608507896 GILSLPHQAS(ph)PVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GILSLPHQASPVSR 14 0 O75925;O75925-2 O75925 PIAS1 E3 SUMO-protein ligase PIAS1 1 GILSLPHQAS(0.964)PVS(0.036)R;GILSLPHQAS(0.992)PVS(0.008)R;GILSLPHQAS(0.983)PVS(0.017)R;GILSLPHQAS(0.998)PVS(0.002)R 122.5 3.2191e-05 59120000.0 183223.0 167462.0 198532.0 221309.0 297214.0 248510.0 235472.0 193577.0 211566.0 199408.0 True False 214239.03508079489 184086.52064219743 203265.7558168025 208909.7742234591 238977.05026855133 235477.69812314768 213166.38749035134 188495.80886178516 214659.75250645087 235559.0918871403 0.9094916836554958 0.7814876478229755 0.8629077068873657 0.8868678026809117 1.0145099828413697 0.9996544656232942 0.9049380594168803 0.8002060432126992 0.9112777213850757 1.0 17.84572949129661 -5.894965514034221 3.558014723995505 0.9310848727965285 0.843922708268339 0.254776278017656 0.0659301352053646 0.3628082566707567 8.904701991852335 0.020942405522366862 0.032624971194598 1.2736042099262884e-06 5.894965514034221 -0.08716216452818948 GILSLPHQAS(ph)PVSR ddPTM_PC-9_Lapatinib_30min_R1 4 GILSLPHQASPVSR 14 0 O75925;O75925-2 O75925 PIAS1 E3 SUMO-protein ligase PIAS1 1 GILSLPHQAS(0.994)PVS(0.006)R;GILSLPHQAS(0.999)PVS(0.001)R;GILSLPHQAS(0.947)PVS(0.053)R;GILSLPHQAS(0.983)PVS(0.017)R 145.94 0.0001071 53196400.0 322342.0 270033.0 309492.0 254289.0 329950.0 315360.0 286856.0 285420.0 331973.0 218242.0 True False 317745.3439697164 269407.75517927826 284046.76243366837 272990.2613432365 310542.9897066591 301872.78794006543 301708.0000828127 298681.6551769376 294582.70490933285 255964.83891081446 1.2413632486469286 1.0525186049992894 1.1097100822220292 1.0665146920368784 1.2132251876003222 1.1793525596116998 1.1787087686208981 1.1668854849279002 1.1508717609920398 1.0 17.965586119767842 -4.72666909114578 24.226467314386333 1.1333674539176202 1.2413644947614908 0.2191307635239037 0.06428838376911399 6636.453973268185 4623593.593363425 0.016095016555501784 3.1729587124228846 1.876423696661214e-05 4.72666909114578 0.10799704084387063 GINSSNVENQLQATQAAR ddPTM_PC-9_Lapatinib_30min_R1 1 GINSSNVENQLQATQAAR 18 0 P52292;J3QLL0;J3KS65 P52292 KPNA2 Importin subunit alpha-1 0 120.3 0.00078416 0.0 3396.5 4011.0 4188.2 3946.0 3815.2 5437.5 4601.0 2559.6 4702.9 3667.4 False True 3348.0652871581833 4001.7127759351065 3843.8623629195276 4236.202003470115 3590.7974369717977 5204.950800431592 4839.217267134099 2678.5283602792 4173.209878267517 4301.305203496672 0.7783835670243607 0.9303484841489469 0.8936502250048952 0.9848643151447072 0.8348157750007418 1.210086370109314 1.1250578692254016 0.6227245530267734 0.9702194289479801 1.0 12.070558787474345 -3.9024474096964923 1.0591446143544145 0.9577612833297701 7.07694564257361e-10 0.11163921171438984 0.1500840353753939 24.775541259177707 5.69201959467365 0.04889902465868465 41.673640423568216 0.00012518508550416371 3.9024474096964923 -0.9577612826220755 GIPAPEEER ddPTM_PC-9_AZD4547_30min_R2 2 GIPAPEEER 9 0 O95433;G3V438;H0YJU2 O95433 AHSA1 Activator of 90 kDa heat shock protein ATPase homolog 1 0 ; 115.49 0.0091017 6225600.0 30476.0 37050.0 61389.0 107961.0 68123.0 53162.0 38124.0 56973.0 40775.0 48258.0 False True 40166.73405982058 49025.68794776117 60574.941749139936 83072.2594308227 58665.29733857447 49837.77173599276 41516.962144025856 48169.13195929697 42930.28325618766 46568.502108591994 0.8625300845227256 1.0527649747771428 1.3007706712980944 1.7838722670767562 1.2597634598977274 1.0702034525348751 0.8915245340555173 1.034371512465067 0.9218738269931797 1.0 15.507066857686638 -6.88324352005388 3.7287919418801367 0.966674435100685 1.2729185638771947 0.2744932293964839 0.22201016079985136 0.3401831495524139 8.987926825531167 0.09118970475109592 0.07991810286861066 1.308448036893629e-07 6.88324352005388 0.30624412877650975 GIPAPEEER ddPTM_PC-9_Lapatinib_30min_R1 1 GIPAPEEER 9 0 O95433;G3V438;H0YJU2 O95433 AHSA1 Activator of 90 kDa heat shock protein ATPase homolog 1 0 93.429 0.028858999999999996 4536100.0 15265.0 18648.0 17917.0 18200.0 18218.0 20709.0 15111.0 13118.0 16549.0 13332.0 False True 15047.31830074185 18604.821701729714 16443.93342162008 19538.488713420207 17146.453057966093 19823.32434503683 15893.373641309143 13727.510169613432 14685.077351304322 15636.41843622665 0.9623251233722445 1.1898390784059494 1.0516432192376337 1.2495501315156157 1.096571643173796 1.267766299929011 1.0164331241281683 0.8779190852177098 0.9391586322147629 1.0 13.932622476848241 -7.503006992009724 8.437192775380435 0.9342218519590542 1.1386764354173196 0.5024948033128371 0.08918972136646434 0.1688243356818896 63.65336751664384 0.036842616410279125 0.02364101368467703 3.140458133043695e-08 7.503006992009724 0.2044545834582654 GIPHLVTHDAR ddPTM_PC-9_AZD4547_30min_R2 2 GIPHLVTHDAR 11 0 P62701;C9JEH7;Q8TD47;P22090 P62701 RPS4X;RPS4Y1;RPS4Y2 40S ribosomal protein S4, X isoform;40S ribosomal protein S4, Y isoform 2;40S ribosomal protein S4, Y isoform 1 0 ; 205.18 2.803e-06 9777400.0 125950.0 122192.0 179214.0 239140.0 183975.0 165265.0 146829.0 203188.0 151618.0 170799.0 False True 165999.48007725392 161688.17440520469 176837.5052636527 184009.96767616947 158433.24688965932 154930.95342441657 159896.49655453733 171789.96339574258 159632.21794571803 164819.37899716958 1.0071599655772554 0.9810022061057597 1.072916949084546 1.1164340552413405 0.9612537545865895 0.9400044725752618 0.9701316527668946 1.0422922622387305 0.9685282089823878 1.0 17.330526354939977 -6.312879415522976 24.998753342805625 0.9799529591222875 1.0418901975186514 0.35405045401848667 0.04230081923832312 445.2171118947335 216364.77478519827 0.014366312225104212 0.016289879225896878 4.865422783309227e-07 6.312879415522976 0.06193723839636389 GIPLATGDT(ph)SPEPELLPGAPLPPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GIPLATGDTSPEPELLPGAPLPPPK 25 0 K7ER90;K7EL20;K7ENA8;O75821;K7EL60 K7ER90 EIF3G Eukaryotic translation initiation factor 3 subunit G 1 GIPLAT(0.009)GDT(0.496)S(0.496)PEPELLPGAPLPPPK 87.052 0.00068855 0.0 18921.0 22754.0 17266.0 21847.0 25803.0 17749.0 19867.0 15888.0 15370.0 13963.0 True False 22123.951593215534 25012.866744052782 17677.68692166964 20622.983418929656 20747.087378385353 16818.211194671232 17985.05393537583 15470.956834727496 15594.757172816768 16494.381368952814 1.3413022955113185 1.516447703284842 1.071739917141976 1.250303540195091 1.2578275543839044 1.0196327354433528 1.0903745665314184 0.9379531422650564 0.9454587488907344 1.0 14.009687049378302 -5.90670673546883 0.4377549956216697 0.9393307232146547 1.5155688999608148 0.6760424662286398 0.10309239329068441 1.201336348053204 0.35745327570593866 0.09001530104236008 0.3290353909038399 1.239633386912216e-06 5.90670673546883 0.5762381767461601 GIPLATGDTS(ph)PEPELLPGAPLPPPK ddPTM_PC-9_AZD4547_30min_R2 4 GIPLATGDTSPEPELLPGAPLPPPK 25 0 K7ER90;K7EL20;K7ENA8;O75821;K7EL60 K7ER90 EIF3G Eukaryotic translation initiation factor 3 subunit G 1 GIPLAT(0.004)GDT(0.202)S(0.794)PEPELLPGAPLPPPK;GIPLAT(0.004)GDT(0.206)S(0.79)PEPELLPGAPLPPPK;GIPLAT(0.011)GDT(0.195)S(0.794)PEPELLPGAPLPPPK;GIPLAT(0.01)GDT(0.174)S(0.816)PEPELLPGAPLPPPK 134.76 2.4796e-09 51752800.0 296049.1 329801.30000000005 393384.7 374036.19999999995 407594.0 443816.2 374883.60000000003 448179.0 407690.8 397945.7 True False 390186.5555961821 436403.12060906785 388168.16184500314 287807.9328916838 351006.6086845688 416064.3028542128 408247.5141542364 378923.2336788621 429240.5033707363 384013.74216824485 1.0160744597135611 1.1364257907673263 1.0108184140840932 0.7494730039259607 0.9140469992107342 1.083462014939887 1.0631065228269208 0.9867439418687457 1.1177738092057046 1.0 18.5507984140375 -6.768966662990537 24.997585776823367 1.0501943345371265 0.9654018434292071 0.15854061475943226 0.09773844738277546 386.8479944365785 1284687.7554280472 0.03820538755000053 0.03434392448539621 1.7022891733115624e-07 6.768966662990537 -0.08479249110791942 GIPLATGDTS(ph)PEPELLPGAPLPPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GIPLATGDTSPEPELLPGAPLPPPK 25 0 K7ER90;K7EL20;K7ENA8;O75821;K7EL60 K7ER90 EIF3G Eukaryotic translation initiation factor 3 subunit G 1 GIPLAT(0.009)GDT(0.171)S(0.82)PEPELLPGAPLPPPK 100.7 8.3306e-07 3957400.0 8803.7 10155.0 12905.0 9814.2 10765.0 8430.2 9766.8 8672.0 10078.0 8098.0 True False 10293.992528999079 11163.12128794305 13212.704142485047 9264.342192065702 8655.6755271991 7988.105471481063 8841.617998491398 8444.369188743505 10225.371684297168 9566.103296267267 1.076090463398596 1.1669455098084656 1.3812002372628256 0.9684551697952798 0.9048277296542032 0.8350427780346105 0.9242653695723141 0.8827386582829952 1.0689171303729441 1.0 13.223715654515255 -5.900864673632067 7.637056244418675 0.9256273781173777 1.2029179836472859 0.6364776312898661 0.09264848364203326 0.14137892897386575 9.58594956383301 0.026283750346627496 0.03915337537533478 1.2564214042146653e-06 5.900864673632067 0.27729060552990814 GIPLATGDTS(ph)PEPELLPGAPLPPPK ddPTM_PC-9_Lapatinib_30min_R1 2 GIPLATGDTSPEPELLPGAPLPPPK 25 0 K7ER90;K7EL20;K7ENA8;O75821;K7EL60 K7ER90 EIF3G Eukaryotic translation initiation factor 3 subunit G 1 GIPLAT(0.01)GDT(0.162)S(0.828)PEPELLPGAPLPPPK;GIPLAT(0.002)GDT(0.11)S(0.888)PEPELLPGAPLPPPK 125.78 2.048e-09 27433100.0 166978.0 249699.0 237637.0 215246.0 268678.0 250186.0 261793.0 265830.0 227441.0 224843.0 True False 164596.86309998526 249120.83730696046 218099.40316534735 231075.90887960634 252874.88828127173 239486.1279920514 275347.36057701317 278181.43226012704 201824.19952009228 263706.8129655352 0.6241661383299074 0.9446886658158467 0.827052591901945 0.8762606710119639 0.9589243654251772 0.908152979814559 1.044142005587847 1.0548890608165045 0.765335552959223 1.0 18.008575318694355 -4.350128284502133 1.8052930095971387 0.9363458014480414 1.832696526969923e-39 0.5089768998843189 0.08874843265430807 3.236505151470244 3.751420472363844 0.024209150717701487 7.630298781302692 4.4655166756462634e-05 4.350128284502133 -0.9363458014480414 GIQLS(ph)PGVGSSAGPPGDLEDDEGLKHLQQEAEK ddPTM_PC-9_Lapatinib_30min_R1 2 GIQLSPGVGSSAGPPGDLEDDEGLKHLQQEAEK 33 1 O75420 O75420 GIGYF1 PERQ amino acid-rich with GYF domain-containing protein 1 1 GIQLS(0.982)PGVGS(0.014)S(0.004)AGPPGDLEDDEGLKHLQQEAEK;GIQLS(0.97)PGVGS(0.023)S(0.006)AGPPGDLEDDEGLKHLQQEAEK 103.42 2.9298e-17 15095800.0 51482.0 38941.0 40706.0 42056.0 43173.0 41758.0 43993.0 44915.0 46353.0 41482.0 True False 50747.85723935745 38850.83450702789 37359.309809704006 45148.93853470329 40633.64902138378 39972.10768265239 46270.742280597806 47001.91487026891 41132.237021270754 48652.10842870939 1.0430762176261896 0.7985436964968652 0.7678867579695363 0.9279955174164888 0.8351878332451887 0.8215904505192015 0.9510531768299203 0.9660817668188311 0.8454358577602529 1.0 15.570214707756879 -7.273096065198208 24.5170998076228 0.9378161864981092 0.859657055453932 0.16713077726574999 0.08117406563910264 1065.1617215445785 2240308.140832144 0.03329704542179455 0.022661024898906118 5.332169357656806e-08 7.273096065198208 -0.07815913104417715 GIQSLGS(ph)PIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GIQSLGSPIK 10 0 O95171-2;O95171;O95171-3;F2Z2X8 O95171-2 SCEL Sciellin 1 GIQS(0.002)LGS(0.998)PIK;GIQS(0.009)LGS(0.991)PIK 107.39 0.0021795 20226800.0 142323.0 191323.0 163170.0 172834.0 199738.0 118450.0 147759.0 138712.0 105109.0 107267.0 True False 166415.472892617 210316.28303034257 167060.59162567093 163150.67131538794 160600.77273123004 112238.27348069231 133762.19783747915 135070.95697751234 106646.02027830831 126713.65797489516 1.313319144536003 1.6597759577898934 1.3184102984286776 1.2875539537159584 1.2674306408473244 0.8857630288199023 1.0556257310792847 1.0659542083795968 0.8416300340681294 1.0 16.951212509812827 -6.3020771186791835 1.1002265809360199 0.9693174545545599 1.4733069843915123 0.7389707158306077 0.11951157020489207 0.24446956756727414 0.6178543899077873 0.05105399845343095 0.07354703115342924 4.987959072485531e-07 6.3020771186791835 0.5039895298369524 GIQSLGS(ph)PIKVNQR ddPTM_PC-9_AZD4547_30min_R2 1 GIQSLGSPIKVNQR 14 1 O95171-2;O95171;O95171-3;F2Z2X8 O95171-2 SCEL Sciellin 1 GIQS(0.096)LGS(0.904)PIKVNQR 56.773999999999994 0.032856 30876000.0 72198.0 64698.0 92378.0 127940.0 144660.0 108080.0 86654.0 85348.0 86379.0 112010.0 True False 95155.46218830976 85610.36326165318 91153.0073612871 98445.40965329566 124576.4560133607 101321.74051439167 94366.03812895868 72159.42770193037 90944.81759377653 108088.56399319085 0.8803471771010315 0.7920390474152871 0.8433177756624594 0.9107846937396387 1.1525405779394804 0.9373955649995918 0.8730436842042176 0.6675953961834123 0.841391672106086 1.0 16.721854365288486 -10.458993500462027 4.041925909570544 1.0000054847571687 0.8785906939038645 0.0912291666325259 0.1158512016761949 90597098.18626487 200967410.10830465 8116.577476433934 0.03226894327317933 3.475413626176969e-11 10.458993500462027 -0.1214147908533042 GIQSLGS(ph)PIKVNQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GIQSLGSPIKVNQR 14 1 O95171-2;O95171;O95171-3;F2Z2X8 O95171-2 SCEL Sciellin 1 GIQS(0.001)LGS(0.999)PIKVNQR;GIQSLGS(1)PIKVNQR 124.68 1.7634e-05 65760000.0 148209.0 91937.0 135818.0 159622.0 191265.0 182167.0 160659.0 156690.0 147333.0 134835.0 True False 173297.85643881807 101063.89776953436 139056.41621263343 150678.89684150627 153787.99625729036 172613.84183332432 145440.21644956685 152577.05352677844 149487.46639834836 159279.51814672718 1.0880109285562836 0.6345065514100502 0.8730338830164945 0.9460029675799366 0.9655227366749185 1.0837164994077497 0.9131131117284543 0.957920109892758 0.9385228442281044 1.0 17.281201236165508 -5.76683035929816 3.613044065849706 0.9742805547820073 0.8385364753473747 0.15972600798712477 0.11064943915810113 0.3334540331538597 9.273599158397667 0.030196756094633105 0.05104033902783667 1.710683398323358e-06 5.76683035929816 -0.13574407943463251 GIQSLGS(ph)PIKVNQR ddPTM_PC-9_Lapatinib_30min_R1 2 GIQSLGSPIKVNQR 14 1 O95171-2;O95171;O95171-3;F2Z2X8 O95171-2 SCEL Sciellin 1 GIQSLGS(1)PIKVNQR;GIQS(0.087)LGS(0.913)PIKVNQR 112.57 0.0001375 58414000.0 396480.0 241190.0 249140.0 247970.0 216610.0 202410.0 162721.0 175695.0 216370.0 203900.0 True False 390826.1224944733 240631.53937366963 228656.6709082113 266206.54100367107 203869.42567164503 193753.3961407554 171145.89718003222 183858.43110613138 192000.13212289044 239143.84332032842 1.6342721479597928 1.0062209255847263 0.9561470106588955 1.1131649358294067 0.8524970697178518 0.81019604540363 0.715660895985458 0.7688194207862448 0.8028646251440815 1.0 17.867519124529316 -1.5228787453007697 0.7621888005235022 0.8304679693464716 147.0525699619174 0.8034206489664553 0.11185272776039308 176.5147809663288 0.7239132241210946 0.04334945001262621 44382.50590416494 0.029999999998588597 1.5228787453007697 146.22210199257094 GIS(ph)PIVFDR ddPTM_PC-9_AZD4547_30min_R2 6 GISPIVFDR 9 0 Q96MU7;Q96MU7-2;J3QR07 Q96MU7 YTHDC1 YTH domain-containing protein 1 1 GIS(1)PIVFDR;GIS(1)PIVFDR;GIS(1)PIVFDR;GIS(1)PIVFDR;GIS(1)PIVFDR;GIS(1)PIVFDR 146.11 0.00045596 261819600.0 112870.3 127946.1 152263.9 156279.0 139790.7 156456.0 146004.4 167228.0 137030.0 121082.7 True False 148760.7075519154 169302.17470264627 150244.78119853506 120251.29103648117 120383.17426812464 146672.78158696945 158998.5087519992 141386.75511714857 144273.12604771066 116843.63152770545 1.273160595976871 1.4489636490158393 1.2858619612735134 1.0291642724915453 1.0302929881084697 1.2552911927612507 1.3607802725157354 1.2100510166326315 1.234753868579489 1.0 16.834219577716482 GIS(ph)PIVFDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 GISPIVFDR 9 0 Q96MU7;Q96MU7-2;J3QR07 Q96MU7 YTHDC1 YTH domain-containing protein 1 1 GIS(1)PIVFDR;GIS(1)PIVFDR;GIS(1)PIVFDR;GIS(1)PIVFDR;GIS(1)PIVFDR;GIS(1)PIVFDR;GIS(1)PIVFDR;GIS(1)PIVFDR 141.88 0.00069293 253096800.0 121744.6 184059.0 165066.8 131792.9 138495.2 113279.8 148261.8 97021.8 102749.9 104751.6 True False 142353.5562145438 202331.161116446 169002.61853132528 124408.97109134709 111358.05975611166 107339.20787030912 134217.3689815224 94475.08055309445 104252.42290378698 123742.23586679074 1.1504039442748413 1.6351018688094234 1.365763414144687 1.0053880974421223 0.8999195705174527 0.8674419620626577 1.0846528514807845 0.7634828956444382 0.8424966800827435 1.0 16.916978481423975 -5.798048802266728 3.4870061370334384 0.9080379442034968 1.4191310764241556 0.7082798519718756 0.13637241695171187 0.11353136805912492 2.854491243070274 0.038048201688590834 0.06302189723130219 1.5920298184244958e-06 5.798048802266728 0.5110931322206588 GIS(ph)PIVFDR ddPTM_PC-9_Lapatinib_30min_R1 6 GISPIVFDR 9 0 Q96MU7;Q96MU7-2;J3QR07 Q96MU7 YTHDC1 YTH domain-containing protein 1 1 GIS(1)PIVFDR;GIS(1)PIVFDR;GIS(1)PIVFDR;GIS(1)PIVFDR;GIS(1)PIVFDR;GIS(1)PIVFDR 143.96 0.00057535 265588000.0 144215.0 156012.4 150100.4 121008.0 148574.0 154791.2 144941.5 136498.0 135649.6 118727.0 True False 142158.46765420772 155651.16287317337 137759.72451629958 129907.33199085429 139835.16942772263 148171.14121191125 152445.86166579387 142840.19539044792 120371.3135943859 139248.80375621642 1.020895431913981 1.1177917416488017 0.9893063408822974 0.9329152458521921 1.0042109207094716 1.064074787107796 1.0947732228470817 1.0257911848242443 0.8644333764268493 1.0 17.087305408304545 -8.156251502278737 8.489047116309816 0.9326833544566846 1.0320560378976444 0.31548680686366104 0.05836858352496764 0.3637976446905813 26.0476015613101 0.0417063390406531 0.01567624634085392 6.97828170981081e-09 8.156251502278737 0.09937268344095984 GIS(ph)PVVSEHR ddPTM_PC-9_AZD4547_30min_R2 2 GISPVVSEHR 10 0 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;F8WB06 Q99700;F8WB06 ATXN2 Ataxin-2 1 GIS(1)PVVSEHR;GIS(1)PVVSEHR 112.85 0.0035499000000000004 8237900.0 31015.0 33215.1 61471.0 96093.0 77985.0 76543.0 53617.0 90499.0 54983.0 72645.0 True False 40877.1248479241 43951.23151831798 60655.85437556211 73940.24347205048 67158.12886908566 71756.7541098547 58388.80913010789 76514.45901013492 57889.2891299808 70101.720661417 0.5831115764669424 0.6269636622843713 0.8652548582726335 1.0547564706603008 0.9580097069721222 1.0236090274649792 0.8329154916484706 1.0914776169288438 0.8257898462946325 1.0 16.097162235471906 -5.330109205159819 2.923411389050401 0.9693680999142367 0.590229193989356 0.755933271563044 0.08170681379617613 0.11280469813389857 1.865503521400981 0.020595798805742645 0.055316770570060375 4.676175421200468e-06 5.330109205159819 -0.37913890592488064 GIS(ph)PVVSEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GISPVVSEHR 10 0 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;F8WB06 Q99700;F8WB06 ATXN2 Ataxin-2 1 GIS(1)PVVSEHR;GIS(1)PVVSEHR 85.554 0.0067047 10346200.0 33023.0 51471.0 102089.0 84138.0 98592.0 71576.0 74431.0 61528.0 71674.0 46699.0 True False 38613.14166601958 56580.70072001142 104523.18893468844 79424.02063907663 79273.60534859406 67822.4285576533 67380.35684622536 59912.955194304726 72722.09665611376 55165.15903091938 0.6999552316051043 1.0256600672228398 1.8947319426035645 1.439749690462425 1.4370230547901113 1.2294431802442496 1.2214295767453425 1.0860651223850233 1.318261343456908 1.0 15.751469763164993 -7.17215905643922 2.5872891833440934 1.158000246379266 1.3240780375118302 0.04379582626379852 0.29862790735900535 1.0586051243379102 13.83704310301687 0.14299142667918616 0.1021149867862991 6.727302297787349e-08 7.17215905643922 0.16607779113256416 GIS(ph)PVVSEHR ddPTM_PC-9_Lapatinib_30min_R1 1 GISPVVSEHR 10 0 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;F8WB06 Q99700;F8WB06 ATXN2 Ataxin-2 1 GIS(1)PVVSEHR 92.792 0.004084 3947100.0 16643.0 12078.0 34658.0 25520.0 30171.0 34973.0 31876.0 25194.0 35723.0 17881.0 True False 16405.66776804759 12050.034133070103 31808.553023748864 27396.825932224354 28396.40109846827 33477.2863160449 33526.383309534154 26364.605215218853 31699.499560133205 20971.707025065167 0.7822762233155225 0.574585279046099 1.5167364767079576 1.306370811850459 1.3540338449573603 1.5963071711822596 1.5986482773893307 1.257151131460503 1.5115364487137977 1.0 14.3561566761945 -5.261395246144443 24.99999999994604 1.4119594295720377 0.678430700213865 0.7179082649823709 0.1787397526183536 1.7557682871901439 993802.2018319189 0.04414482248189318 0.10258741458504561 5.4777821168911534e-06 5.261395246144443 -0.7335287293581727 GIS(ph)SLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GISSLPR 7 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 GIS(0.627)S(0.373)LPR 71.877 0.040286 27610000.0 36704.0 36223.0 82455.0 87083.0 100030.0 87440.0 70569.0 66735.0 67685.0 64519.0 True False 42917.26226295556 39818.9800505328 84421.03991232874 82204.02183689528 80429.83957136309 82854.49247067739 63884.193444683966 64983.27696157732 68674.76507756049 76215.78396787713 0.5631020246546833 0.5224505735887387 1.1076582240223352 1.0785695240180437 1.0552911140461676 1.087104116197221 0.8382016180744059 0.8526222991941669 0.9010569924269889 1.0 16.217802184277012 -5.253585947297611 24.99164997036386 0.9883321560429734 0.542776234026105 0.7879154819778107 0.09282059580259765 285.5784603416684 908779.0520156267 0.027268761072675982 0.0693925136834051 5.577172184426096e-06 5.253585947297611 -0.44555592201686844 GISCMNT(ph)TLSESPFKCDPDAAR ddPTM_PC-9_Lapatinib_30min_R1 1 GISCMNTTLSESPFKCDPDAAR 22 1 Q15181 Q15181 PPA1 Inorganic pyrophosphatase 1 GIS(0.027)CMNT(0.372)T(0.118)LS(0.208)ES(0.275)PFKCDPDAAR 50.226000000000006 0.024253999999999998 8809600.0 58264.0 50589.0 52832.0 52510.0 58854.0 61590.0 44004.0 44499.0 58474.0 48287.0 True False 57433.144675691 50471.86427867892 48488.35689741762 56371.76056822496 55392.32343141592 58955.93927330236 46282.31180677441 46566.58599158623 51888.04236148221 56633.34361161689 1.0141224411816303 0.8912040338781252 0.8561803666395476 0.9953811124911532 0.9780867577109397 1.0410110990022678 0.8172272526265034 0.8222468076568639 0.9162101167348116 1.0 15.789364088069938 -10.164162129713345 5.0042582243925855 1.0000000050028837 0.92342198428778 0.07893593928235165 0.07572668372332958 110316199.89597572 434507436.4237981 31.637026450895224 0.02021614448413863 6.852323694892696e-11 10.164162129713345 -0.07657802071510367 GISCMNTTLSES(ph)PFKCDPDAAR ddPTM_PC-9_Lapatinib_30min_R1 1 GISCMNTTLSESPFKCDPDAAR 22 1 Q15181 Q15181 PPA1 Inorganic pyrophosphatase 1 GIS(0.075)CMNT(0.066)T(0.035)LS(0.283)ES(0.541)PFKCDPDAAR 55.788999999999994 0.019356 7366800.0 21878.0 24842.0 23244.0 25775.0 26519.0 22589.0 24627.0 21113.0 22566.0 18787.0 True False 21566.015708066163 24784.47987528793 21332.968044434732 27670.579482879424 24959.204558360012 21622.921127530888 25902.06555916355 22093.987056795882 20024.379449485357 22034.307917896043 0.9787471332626001 1.1248131762358746 0.9681705513023311 1.255795261915427 1.1327428413618745 0.9813297158277873 1.1755334297623279 1.0027084644147761 0.9087818652666535 1.0 14.427463962840559 -7.9841133779182485 16.114565388168355 0.9548407631181571 1.0890199490307069 0.2743242185390481 0.0900078166338354 4.445560580513538 4509.1551229239985 0.04822490988993035 0.023068452524989604 1.0372575916113976e-08 7.9841133779182485 0.13417918591254974 GISEDSHLESLQDVGQSAAPT(ph)FMISPETVTGTGKK ddPTM_PC-9_AZD4547_30min_R2 2 GISEDSHLESLQDVGQSAAPTFMISPETVTGTGKK 35 1 E7EVA0;P27816;P27816-6 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 GISEDSHLESLQDVGQS(0.05)AAPT(0.898)FMIS(0.05)PET(0.001)VTGTGKK;GISEDSHLESLQDVGQS(0.002)AAPT(0.491)FMIS(0.491)PET(0.013)VT(0.001)GT(0.001)GKK 105.44 1.4291e-21 50975500.0 46474.0 33204.0 82545.0 127815.0 116425.0 87402.0 67037.0 96303.0 64245.0 91901.0 True False 61251.765280748805 43936.54366039033 81450.39936605509 98349.22647206498 100261.3983917843 81936.73912323169 73003.16313212321 81421.58417278659 67640.85954123299 88683.57396248745 0.6906776818293079 0.49543045794450263 0.9184383953730604 1.1089903358390363 1.1305520730839533 0.9239223845206145 0.8231869766886374 0.9181134739475809 0.7627213983261952 1.0 16.436379291771573 -5.31570221273109 6.908560470647935 0.9533161083831704 0.5937522663481684 0.6025003237676898 0.11541541683652956 0.15344364101223507 16.50681613136513 0.03291090256069067 0.06983199485358907 4.833901396362649e-06 5.31570221273109 -0.359563842035002 GISEDSHLESLQDVGQSAAPT(ph)FMISPETVTGTGKK ddPTM_PC-9_Lapatinib_30min_R1 1 GISEDSHLESLQDVGQSAAPTFMISPETVTGTGKK 35 1 E7EVA0;P27816;P27816-6 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 GISEDSHLESLQDVGQS(0.007)AAPT(0.487)FMIS(0.487)PET(0.012)VT(0.003)GT(0.004)GKK 92.788 4.0432e-13 15369000.0 114090.0 65185.0 88478.0 70478.0 84786.0 89965.0 69465.0 59253.0 95309.0 56345.0 True False 112463.05567845669 65034.06813745445 81203.68037495665 75661.18722771591 79799.05417568964 86117.40666865808 73061.55780514465 62006.110693711336 84574.29677173632 66084.15817500679 1.701815666330006 0.9841098068500556 1.2287919316443394 1.1449217076707983 1.2075368194047733 1.3031475174518894 1.1055835441174877 0.9382900895779621 1.2797968394749493 1.0 16.012016847022945 -4.751472739320133 24.999904983832565 1.140775200540074 1.7018168023973717 0.6682705526475614 0.12021377655567791 248.22162504918094 622586.2172434134 0.029388284944008577 0.3869689974404683 1.7722592864213632e-05 4.751472739320133 0.5610416018572977 GISEDSHLESLQDVGQSAAPTFMIS(ph)PETVTGTGK ddPTM_PC-9_AZD4547_30min_R2 1 GISEDSHLESLQDVGQSAAPTFMISPETVTGTGK 34 0 E7EVA0;P27816;P27816-6 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 GISEDSHLESLQDVGQSAAPT(0.006)FMIS(0.946)PET(0.046)VT(0.001)GT(0.001)GK 137.88 7.5021e-22 4553600.0 28998.0 30136.0 57978.0 74456.0 59013.0 59332.0 43970.0 68493.0 51173.0 53706.0 True False 38218.76080413033 39876.87265840026 57209.17383784774 57291.3195337329 50820.06358852802 55621.96066062077 47883.2448188232 57908.98066256165 53877.90030824996 51825.769286834184 0.737447052500182 0.7694410176084078 1.1038750533777635 1.1054600891044986 0.9805944858678315 1.0732491080407556 0.923927333404532 1.1173781201791604 1.0395967305387805 1.0 15.661382005993904 -5.2518219255176035 24.129779965160154 1.0440304245751821 0.7534439387429681 0.7953975586130072 0.05874318264857593 169.83242800228362 426098.3734918673 0.014765385813092073 0.03794192806693809 5.599871668885945e-06 5.2518219255176035 -0.290586485832214 GISEDSHLESLQDVGQSAAPTFMIS(ph)PETVTGTGKK ddPTM_PC-9_AZD4547_30min_R2 3 GISEDSHLESLQDVGQSAAPTFMISPETVTGTGKK 35 1 E7EVA0;P27816;P27816-6 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 GISEDSHLESLQDVGQS(0.001)AAPT(0.1)FMIS(0.879)PET(0.015)VT(0.003)GT(0.001)GKK;GISEDSHLESLQDVGQSAAPT(0.002)FMIS(0.995)PET(0.002)VTGTGKK;GISEDSHLESLQDVGQS(0.005)AAPT(0.069)FMIS(0.867)PET(0.037)VT(0.011)GT(0.011)GKK 160.69 9.2114e-24 157146000.0 159667.0 127904.0 274415.0 484330.0 418112.0 322254.0 210807.0 317302.0 234658.0 323418.0 True False 210437.78472008737 169246.46670095666 270776.0778004245 372675.201323907 360064.3659384653 302103.40643712855 229568.4146127282 268270.2667745922 247061.54281619834 312095.23426077765 0.6742742650925958 0.5422910961836068 0.8676072175269806 1.1941073121690493 1.1537003017406091 0.9679846831134236 0.7355716762432443 0.8595782226858146 0.7916222860672103 1.0 18.251626801700866 -5.382987998170066 4.80999263183619 0.9559688913343486 0.611610378907828 0.49343274513516744 0.13898173749520976 0.19980998814051854 6.90511525385977 0.04196260582400761 0.09091340443267888 4.140111159559964e-06 5.382987998170066 -0.3443585124265206 GISEDSHLESLQDVGQSAAPTFMIS(ph)PETVTGTGKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GISEDSHLESLQDVGQSAAPTFMISPETVTGTGKK 35 1 E7EVA0;P27816;P27816-6 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 GISEDSHLESLQDVGQS(0.001)AAPT(0.078)FMIS(0.688)PET(0.078)VT(0.078)GT(0.078)GKK;GISEDSHLESLQDVGQSAAPT(0.016)FMIS(0.965)PET(0.016)VT(0.001)GT(0.001)GKK;GISEDSHLESLQDVGQS(0.003)AAPT(0.009)FMIS(0.808)PET(0.08)VT(0.067)GT(0.032)GKK 124.16 9.2114e-24 154668000.0 91992.0 72000.0 121573.0 147856.0 176799.0 180882.0 162125.0 159721.0 169538.0 126885.0 True False 107564.4286751802 79147.68416857695 124471.76138817013 139572.10767561937 142156.5051122411 171396.22949543776 146767.34631664594 155528.49298838835 172017.17251561553 149888.24607889235 0.7176308449067088 0.5280446348469396 0.830430434969901 0.9311744671570633 0.9484166292626994 1.1434934624908806 0.9791784890150509 1.0376296811594372 1.147636169050079 1.0 17.193527729046437 -5.696380824677122 1.3740063886707723 1.0508848932903234 0.6094453095446704 0.8143464772651932 0.07811078884898076 0.17476779106573356 0.6495957097300665 0.025105678294450307 0.06646482147028858 2.0119592268470614e-06 5.696380824677122 -0.44143958374565306 GISEDSHLESLQDVGQSAAPTFMIS(ph)PETVTGTGKK ddPTM_PC-9_Lapatinib_30min_R1 4 GISEDSHLESLQDVGQSAAPTFMISPETVTGTGKK 35 1 E7EVA0;P27816;P27816-6 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 GISEDSHLESLQDVGQS(0.022)AAPT(0.085)FMIS(0.893)PETVTGTGKK;GISEDSHLESLQDVGQS(0.007)AAPT(0.091)FMIS(0.885)PET(0.005)VT(0.005)GT(0.007)GKK;GISEDSHLESLQDVGQS(0.023)AAPT(0.238)FMIS(0.627)PET(0.072)VT(0.029)GT(0.012)GKK;GISEDSHLESLQDVGQS(0.001)AAPT(0.083)FMIS(0.866)PET(0.032)VT(0.009)GT(0.009)GKK 107.13 1.2703e-21 56425600.0 205917.0 108575.0 179340.0 128389.0 163216.0 173602.0 112899.0 132779.0 189916.0 106558.0 True False 202980.58581944703 108323.60125832834 164595.35747241933 137831.1553531485 153615.95577500248 166177.4471460275 118744.3578009505 138948.39707357108 168525.6601758603 124976.40832038988 1.624151218197001 0.8667523952251024 1.3170114238717936 1.1028573888905828 1.2291596297214125 1.3296705304573526 0.9501341844977423 1.1117970098593533 1.3484597808558192 1.0 16.93129625883288 -1.522878748259201 0.01968276499988294 1.5423231104915935e-07 2.681875398459196 0.10079109054142243 0.20394651553086798 9094.418655178082 13.849308723159059 703.4666733839775 1257.6216711184225 0.029999999794227405 1.522878748259201 2.681875244226885 GISEDSHLESLQDVGQSAAPTFMISPET(ph)VTGTGK ddPTM_PC-9_AZD4547_30min_R2 1 GISEDSHLESLQDVGQSAAPTFMISPETVTGTGK 34 0 E7EVA0;P27816;P27816-6 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 GISEDSHLESLQDVGQSAAPT(0.006)FMIS(0.386)PET(0.563)VT(0.031)GT(0.013)GK 122.06 2.7570999999999998e-24 3999000.0 16193.0 16280.0 33917.0 35508.0 34480.0 30596.0 25246.0 39911.0 26969.0 28854.0 True False 21342.037164676265 21542.19162724835 33467.23841902588 27322.179193131335 29693.04716812307 28682.827283293238 27492.845092017535 33743.67201354155 28394.526281695296 27843.830242474058 0.7664907083121163 0.7736791755893935 1.2019624501220258 0.9812651117033828 1.066413884495968 1.030132242350025 0.9873945090384469 1.2118904518412 1.0197780274633763 1.0 14.765070063858625 -5.242569495743916 24.36982287079611 1.0633430746368664 0.7700848160740528 0.6919768084502933 0.07799687512019438 307.6626202521943 397333.7018550238 0.018976715776287956 0.05000092660944681 5.720454086994533e-06 5.242569495743916 -0.2932582585628136 GISEETTTGVHNLYK ddPTM_PC-9_AZD4547_30min_R2 2 GISEETTTGVHNLYK 15 0 P23526;P23526-2 P23526 AHCY Adenosylhomocysteinase 0 ; 90.861 0.0045279 6115000.0 43700.0 30833.0 55223.0 99329.0 71130.0 58228.0 54277.0 65522.0 47880.0 59050.0 False True 57595.6909835332 40799.16427782239 54490.70693793277 76430.23366775202 61254.827293172595 54586.99395514437 59107.54785151854 55397.08044577358 50410.83905104269 56982.67747342117 1.0107578923506702 0.7159924048295665 0.9562679283252222 1.3412889154498209 1.0749727813640226 0.957957687765826 1.0372897601922704 0.9721740518706378 0.8846695396957465 1.0 15.798235791433648 -5.52066391239381 24.997661646874878 1.0440388098061233 0.8565638694690112 0.22082635580076238 0.1314567240445591 113.19038003647168 1277518.776981558 0.036771877421467584 0.06504572969958598 3.015338602538132e-06 5.52066391239381 -0.1874749403371121 GISHVIVDEIHER ddPTM_PC-9_AZD4547_30min_R2 2 GISHVIVDEIHER 13 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 0 ; 128.36 4.4519e-05 8403000.0 30487.0 27970.0 43989.0 50810.0 39766.0 47363.0 34916.0 47478.0 40180.0 42336.0 False True 40181.23183100634 37010.75551683884 43405.67711809801 39096.539506674635 34245.17731112475 44401.38412271595 38023.45635874533 40141.36603590299 42303.83277090426 40853.82952607552 0.9835364835347962 0.9059311194613033 1.0624628736553017 0.9569859168703079 0.8382366526806819 1.0868353013118675 0.9307195139314012 0.9825606681567565 1.0354924681884046 1.0 15.318183698540443 -6.787126705075227 24.9997403819281 1.0012564167804299 0.9537130989013544 0.16041919401146376 0.06493615693412033 535.7361623630866 521392.1723189201 0.022935479064075993 0.02023411316098484 1.6325755757604993e-07 6.787126705075227 -0.04754331787907551 GISHVIVDEIHER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GISHVIVDEIHER 13 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 0 ; 154.67 3.4898000000000004e-05 8424200.0 23847.3 27376.0 35641.0 33131.0 35279.0 30246.0 34524.0 30972.0 28745.0 26362.0 False True 27884.176884355405 30093.70835831893 36490.816609245216 31274.777482151232 28366.33320242053 28659.84651496007 31253.636787885174 30159.017817546577 29165.341244802737 31141.221918522824 0.8954104934389191 0.9663624772674436 1.1717849962573386 1.0042887065889015 0.9108933900101143 0.9203186242962795 1.0036098413111878 0.9684596801131933 0.9365509587616782 1.0 14.92653793351063 -6.019737464258522 24.445158884933857 0.9557757968857661 1.0202591449262277 0.115773282644691 0.070354895326248 1156.8728145377447 1432805.6348093478 0.02177465144435387 0.028557888205213496 9.555700639627628e-07 6.019737464258522 0.06448334804046163 GISHVIVDEIHER ddPTM_PC-9_Lapatinib_30min_R1 2 GISHVIVDEIHER 13 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 0 ; 198.97 2.5534e-07 6541400.0 32045.0 35230.0 40864.0 35296.0 40007.0 41532.0 41262.0 40866.0 42624.0 35204.0 False True 31588.032423666722 35148.42709952477 37504.31965960163 37891.785584004356 37653.86691678828 39755.77317582066 43398.34446348345 42764.7835486677 37823.236269381545 41288.964493618594 0.7650478235788355 0.8512789683780306 0.908337618043148 0.917721867058708 0.9119595848088626 0.9628668014177275 1.051088226496716 1.0357436683905503 0.9160616337381701 1.0 15.333468616454082 -3.121884293428137 0.37191357299682937 1.0071113821273963 4.888411232385909e-10 0.765619278030077 0.039428971663392716 10.049006044710964 0.413354704129069 0.034234933493155074 5.830228390152958 0.0007552934293302149 3.121884293428137 -1.007111381638555 GISS(ph)LPR ddPTM_PC-9_AZD4547_30min_R2 2 GISSLPR 7 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 GIS(0.036)S(0.964)LPR;GIS(0.114)S(0.886)LPR 86.833 0.018348 37874300.0 61227.0 66200.0 123005.0 189242.0 207423.0 185844.0 136716.0 184691.0 151213.0 160689.0 True False 80695.91239928572 87597.85538844224 121373.87332996076 145615.18065975452 178625.8968316003 174223.1453012267 148883.45914601383 156151.24972696765 159205.8104725423 155063.32701992517 0.5204061717888753 0.5649166509705172 0.7827374509664982 0.9390691110416031 1.1519544966853923 1.1235612484881068 0.9601461674228282 1.007015989711756 1.0267147850638136 1.0 17.242497999092933 -5.540203021448476 1.75612739260279 1.0445815516562287 0.5201861174102062 0.9238260512465334 0.056941650954206106 0.10158941087237541 0.608271852984598 0.019114944699878733 0.05308528311382081 2.882683607997526e-06 5.540203021448476 -0.5243954342460225 GISS(ph)LPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GISSLPR 7 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 GIS(0.328)S(0.672)LPR;GIS(0.172)S(0.828)LPR;GIS(0.331)S(0.669)LPR 84.743 0.01975 50002000.0 62011.0 80565.0 130733.0 154621.0 178444.0 155255.0 152667.0 130275.0 129498.0 120592.0 True False 72508.23752692174 88562.96076446377 133850.1705276636 145958.08665804585 143479.17917097203 147113.15448919265 138205.27654663613 126855.41928777234 131391.66326385314 142454.37499425298 0.5089927040138075 0.6216935125231264 0.9396002792688081 1.0245953250922215 1.0071939115717603 1.0327036603482878 0.9701722151545835 0.8904985844968963 0.9223420710606737 1.0 17.12014040417572 -5.205958598322217 2.941297297344447 0.9783127216465984 0.5247962723915213 0.9380601103801983 0.04248240404997776 0.06561138695450522 1.1009562931443513 0.013111363806737861 0.04336734212705201 6.223596124345724e-06 5.205958598322217 -0.45351644925507717 GISS(ph)LPR ddPTM_PC-9_Lapatinib_30min_R1 2 GISSLPR 7 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 GIS(0.463)S(0.537)LPR;GIS(0.047)S(0.953)LPR 77.318 0.02997 81695000.0 327220.0 259370.0 297160.0 259260.0 208613.0 189791.0 156571.0 176773.0 203962.0 138609.0 True False 322553.78279520123 258769.44470064514 272728.65187077184 278326.845266006 196342.79348893854 181674.0813544299 164677.48027221326 184986.51892156384 180989.651744923 162567.38096511667 1.9841236346448496 1.591767322352147 1.6776345306891136 1.712070672564558 1.2077625432808647 1.1175309602448051 1.0129798443855682 1.1379067425663814 1.113320831463474 1.0 17.310678285104615 -6.322357233438965 2.7757623618330416 1.0828165522230369 1.738038200664799 0.9061769818882857 0.10205335466266953 0.07922087755639651 1.2032610982354717 0.033239295934414215 0.04002527660642277 4.7603925468024333e-07 6.322357233438965 0.6552216484417621 GISSS(ph)NEGVEEPSK ddPTM_PC-9_AZD4547_30min_R2 1 GISSSNEGVEEPSK 14 0 Q9NXV6 Q9NXV6 CDKN2AIP CDKN2A-interacting protein 1 GIS(0.302)S(0.302)S(0.395)NEGVEEPSK 118.13 0.00012012 8308400.0 11143.0 13074.0 14905.0 23012.0 14456.0 17511.0 13278.0 15142.0 14303.0 11048.0 True False 14686.242211201617 17299.914823995397 14707.349961246002 17706.938931855868 12449.03392872352 16416.034401808978 14459.716277105628 12802.151828544658 15059.027379846772 10661.212882749476 1.3775395325765323 1.6226966869771229 1.3795193964322234 1.660874717219729 1.1676939636827675 1.5397905081110586 1.3562918624861504 1.200815701678686 1.4125060202308914 1.0 13.380083956519815 -11.277918467478845 0.15585514676618215 0.45962884173636215 1.5979580276960954 0.46943003946652895 0.14308134095580494 31.224210360386436 0.7642667049301718 7.042176949270218 0.7618462224168 5.273288505118172e-12 11.277918467478845 1.1383291859597333 GITGVEDK ddPTM_PC-9_Lapatinib_30min_R1 2 GITGVEDK 8 0 P29401;P29401-2;A0A0B4J1R6;E9PFF2 P29401 TKT Transketolase 0 ; 115.49 0.016732 22178000.0 129160.0 132061.0 134872.0 134902.0 136486.0 92128.0 178843.0 127997.0 107943.0 139272.0 False True 127318.15471495678 131755.22086830376 123783.34478097543 144823.14309987988 128458.16182180047 88187.90020085724 188102.6154544802 133944.20789602172 95785.32264981822 163344.97963172497 0.7794433290940823 0.8066071033548567 0.7578031786471516 0.8866090860361663 0.7864224668025931 0.5398874235356623 1.1515665548985552 0.8200081092055 0.5863989384049286 1.0 17.317562589012503 -7.244292275117115 24.99909873964501 0.8744941352897619 0.7685345574145587 0.13706144105601814 0.15707107547760027 2126.073946259005 3099649.244765468 0.06063547307334448 0.046856640909846356 5.6978068746914696e-08 7.244292275117115 -0.10595957787520327 GITSENER ddPTM_PC-9_AZD4547_30min_R2 1 GITSENER 8 0 A0A669KAX3;O76024;A0A669KB26;A0A669KBF0;H0Y9G5 A0A669KAX3 WFS1 Wolframin 0 104.45 0.017775 19730000.0 36374.0 43117.0 48565.0 51205.0 52532.0 41301.0 49310.0 70908.0 43972.0 43767.0 False True 47940.17537379946 57053.72705110978 47920.996368192704 39400.478359363784 45238.838568324856 38718.441941014964 53698.49447387247 59950.79790374092 46296.2701493828 42234.73065163802 1.1350889335419536 1.3508722838012708 1.1346348284651402 0.9328928526701918 1.071128852258238 0.916744142643498 1.2714297840985485 1.419466798503563 1.096165867168547 1.0 15.366142229942776 -10.464747643562685 14.380706644183359 0.9999998630596308 1.1494836050582549 0.07576332685154452 0.1545342511648694 0.0 0.0 0.16230272128203505 0.03936419195123612 3.429670172463209e-11 10.464747643562685 0.14948374199862402 GIVCRS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GIVCRSR 7 1 Q5VT98 Q5VT98 PRAMEF20 PRAME family member 20/21 1 GIVCRS(1)R 57.102 0.04177 1196000.0 4251.3 5783.5 9687.0 6925.2 12013.0 8326.1 6299.2 7870.9 9428.3 7881.0 True False 4970.961122997577 6357.647658180072 9917.974818152074 6537.203495801329 9659.13888604206 7889.464658738642 5702.494173741348 7664.2972149079005 9566.171050908808 9309.762914038329 0.533951419482637 0.6829011347424627 1.0653305470536325 0.702187967208465 1.0375279129264292 0.8474399113689568 0.6125283991005264 0.8232537483152008 1.0275418546356145 1.0 13.184528712693586 -5.0281230272919455 6.605392063490589 0.8710982259577764 0.5671694410380205 0.3934281875463027 0.1435086524520568 0.16005582159974788 26.598540917417854 0.0362989611571147 0.10786543909983022 9.372964512177658e-06 5.0281230272919455 -0.30392878491975595 GIVCRS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 GIVCRSR 7 1 Q5VT98 Q5VT98 PRAMEF20 PRAME family member 20/21 1 GIVCRS(1)R 74.439 0.020502 0.0 7598.3 6928.4 9002.9 6428.4 7478.4 7071.8 6415.4 5596.4 10383.0 6211.7 True False 7489.946848642439 6912.357715479623 8262.716314198993 6901.165980513755 7038.535215100098 6769.3555991709645 6747.558021206716 5856.429174662653 9213.557202162836 7285.384068430027 1.0280785169719262 0.9487979838198441 1.1341497217702041 0.9472617937081429 0.9661172491372684 0.9291693527187971 0.9261773926849116 0.8038600463138922 1.2646632100136244 1.0 12.830789314469218 -4.122929146850539 5.6236419398503426 0.9835234254973555 8.943991055400135 0.004865525583462205 0.11972943496199596 17921.543814217144 2232.46669765013 0.028640963692830472 1820736.5588872037 7.534784802591904e-05 4.122929146850539 7.960467629902779 GIVDQSQQAYQEAFEISKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GIVDQSQQAYQEAFEISKK 19 1 P63104;B0AZS6;P63104-2;B7Z2E6;H0YB80 P63104 YWHAZ 14-3-3 protein zeta/delta 0 58.711999999999996 0.014925999999999998 3896600.0 4796.1 6175.2 5327.4 6360.4 8593.8 6865.8 6956.0 6407.8 6080.7 4789.4 False True 5607.985002707094 6788.233045524947 5454.425420277011 6004.0474086950235 6909.90658110948 6505.74536144987 6297.0773229211345 6239.602039625309 6169.618733945798 5657.680307130461 0.9912163109745287 1.1998261967841541 0.9640745189159442 1.0612206916548519 1.2213321018511454 1.1498962486888098 1.1130139882567829 1.1028551810821554 1.0904855698845572 1.0 12.46599494277694 -4.715530975627145 24.004412906413645 1.1037658052178476 0.9912136738587627 0.1555987117164609 0.07584936467877304 16491.34564848488 8621805.598830832 0.018929735197654663 12.655943660172944 1.9251697293416874e-05 4.715530975627145 -0.11255213135908493 GIVEFSGKPAAR ddPTM_PC-9_AZD4547_30min_R2 1 GIVEFSGKPAAR 12 1 Q15233;Q15233-2;H7C367;C9IZL7 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 118.23 0.0014985 0.0 12279.0 14931.0 16336.0 25104.0 22407.0 20919.0 16696.0 19548.0 10010.0 16881.0 False True 16183.466580933746 19757.15375838116 16119.373966247218 19316.660652933682 19296.174822973706 19610.931623062195 18181.91165556225 16527.305768352333 10539.10816417998 16290.001328176497 0.9934601142690835 1.2128392969623394 0.9895256385501855 1.185798592878076 1.184541022080673 1.2038631076807558 1.116139359922172 1.0145674905357667 0.6469679131302887 1.0 13.991699101040478 -8.029011168016902 4.846091857936224 0.8201356884376108 1.1291852813462262 0.5456539615895286 0.10950474125173701 0.13312152611787725 7.918775947636103 0.06946046540694148 0.026914978419084287 9.353816202106572e-09 8.029011168016902 0.30904959290861544 GIVEFSGKPAAR ddPTM_PC-9_Lapatinib_30min_R1 1 GIVEFSGKPAAR 12 1 Q15233;Q15233-2;H7C367;C9IZL7 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 89.9 0.0093852 7001900.0 26185.0 24333.0 29021.0 26323.0 34690.0 38461.0 24969.0 22530.0 28366.0 30008.0 False True 25811.597098259095 24276.65843351505 26635.00540429962 28258.88123095384 32649.602403164106 36816.11268696999 26261.772645744702 23576.82604980871 25171.122372777714 35194.84281685338 0.7333914583047654 0.6897788565172948 0.75678716745242 0.8029267633899422 0.9276814382455357 1.0460655522331315 0.7461824103720391 0.6698943414095524 0.7151934874027704 1.0 15.103076422399463 -5.716310176728702 2.794316130661347 0.8399500524569451 0.7143666820606656 0.19022332507620898 0.1143782340149798 0.5231186625437804 8.293801874950008 0.036728906155016436 0.06774555688509049 1.9217187311747645e-06 5.716310176728702 -0.12558337039627954 GIVVTAYS(ph)PLGSPDRPWAKPEDPSLLEDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GIVVTAYSPLGSPDRPWAKPEDPSLLEDPR 30 2 P15121;E9PCX2 P15121 AKR1B1 Aldose reductase 1 GIVVT(0.011)AY(0.143)S(0.41)PLGS(0.41)PDRPWAKPEDPS(0.025)LLEDPR 40.519 0.022109 5897400.0 10796.0 11126.0 12166.0 11822.0 15888.0 14130.0 14847.0 13012.0 15035.0 11860.0 True False 12623.549569280416 12230.515750827597 12456.083579811931 11159.651667441129 12774.860452962303 13388.997925556627 13440.584677028479 12670.448787353613 15254.858431574508 14010.124116291652 0.9010305308145801 0.8729769736019226 0.889077318403439 0.7965419560033836 0.9118306409653484 0.9556659037722051 0.9593480090157884 0.9043780541972358 1.0888453453339089 1.0 13.774182116272163 -7.386313806229773 0.7935326229874267 1.0200544426029696 0.8677745747378299 0.5767664561787326 0.04875925822366069 0.4908117941834789 0.5902757018563454 0.04141880885365441 0.023089948783434792 4.108527457864779e-08 7.386313806229773 -0.1522798678651397 GIVVY(ph)TGDR ddPTM_PC-9_AZD4547_30min_R2 1 GIVVYTGDR 9 0 P05023-2;P05023-3;P05023-4;P05023 P05023-2 ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 1 GIVVY(0.874)T(0.126)GDR 82.279 0.027533999999999996 0.0 10621.0 17416.0 43392.0 38146.0 30993.0 34026.0 19601.0 45032.0 25959.0 22577.0 True False 13998.257069476118 23045.381411557584 42816.59372817087 29352.02904982505 26690.156928121745 31898.348841068626 21345.451027831557 38073.33913241469 27331.139743651143 21786.586101903973 0.6425172353300815 1.0577784561457109 1.9652731973656508 1.3472523374031473 1.2250729326422205 1.464127913013456 0.9797519872085942 1.7475587480448525 1.2544939173036669 1.0 14.411152527370097 -4.997855790490509 7.430716288797737 1.3913173885623153 0.7373935907470334 0.3779954597394086 0.29012757074022955 0.10922139217154331 45.27216166245358 0.07010246275212233 0.2407357884702615 1.004949433030671e-05 4.997855790490509 -0.653923797815282 GIVVY(ph)TGDR ddPTM_PC-9_Lapatinib_30min_R1 2 GIVVYTGDR 9 0 P05023-2;P05023-3;P05023-4;P05023 P05023-2 ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 1 GIVVY(0.911)T(0.089)GDR;GIVVY(0.902)T(0.098)GDR 120.46 0.0024299 3344500.0 79844.0 93617.0 64559.0 42544.0 61707.0 47505.0 35832.0 40717.0 64253.0 45497.0 True False 78705.40991840378 93400.23558831148 59251.208224946684 45672.827682623574 58077.515580629784 45473.3218895637 37687.205632677484 42608.860464716454 57016.15052591435 53361.09582905818 1.4749586509717847 1.7503432816956823 1.1103821483493785 0.8559199726507885 1.0883868608448488 0.8521811852447165 0.7062674603499173 0.7985004768495306 1.0684966198701225 1.0 15.703500673712774 -5.422062079379454 3.7686203078200213 0.9011512980656395 1.608798548466088 0.8184193268957304 0.13016049102106436 0.08932595522710057 2.2704001729023093 0.03600276844131187 0.08028902466441805 3.783884928444999e-06 5.422062079379454 0.7076472504004485 GIVVYT(ph)GDR ddPTM_PC-9_Lapatinib_30min_R1 1 GIVVYTGDR 9 0 P05023-2;P05023-3;P05023-4;P05023 P05023-2 ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 1 GIVVY(0.354)T(0.646)GDR 91.9 0.010142 0.0 25973.0 20227.0 24119.0 13159.0 18975.0 15955.0 16187.0 13623.0 18402.0 9142.0 True False 25602.620257135153 20180.165624243178 22136.028922032398 14126.756757137171 17858.927806285355 15272.64184292156 17025.08365640072 14255.974313206583 16329.372978349274 10722.182519050712 2.387817984971392 1.8820949548646397 2.0645077513558507 1.317526234237979 1.665605652072643 1.4243967415948933 1.5878375159302953 1.329577657149296 1.5229523419635833 1.0 13.388310978342028 -1.5228787452803376 0.2784296504984107 1.2456723016337008 9.382132487792731 0.7469116031487935 0.1926748114055572 25.6379379907454 0.3609062506563983 0.20500646047976984 101.28706670337127 0.029999999999999995 1.5228787452803376 8.13646018615903 up GIYAVGDVCGK ddPTM_PC-9_Lapatinib_30min_R1 1 GIYAVGDVCGK 11 0 P00390-5;P00390-4;P00390-2;P00390-3;P00390 P00390-5 GSR Glutathione reductase, mitochondrial 0 94.85 0.024587 0.0 32557.0 28876.0 24124.0 22321.0 20551.0 25287.0 22018.0 20838.0 24593.0 19371.0 False True 32092.731209777427 28809.139396136154 22140.61784133297 23962.56080067319 19342.230584820565 24205.53395687607 23157.984305098584 21806.209552859043 21823.0773642291 22719.251539764973 1.4125787178158695 1.2680496690532341 0.9745311284828536 1.054724921669716 0.8513586176448776 1.0654195150095367 1.0193110571695423 0.9598119689238946 0.9605544146572205 1.0 14.4716276872065 -5.105622662782539 2.525279972316865 0.9835518661085352 1.412657387302972 0.861475955191753 0.05808510579424336 0.10336323593034034 1.1870274377731704 0.015278858486043252 0.06888649110920275 7.841106222274844e-06 5.105622662782539 0.4291055211944368 GIYAYGFEKPSAIQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GIYAYGFEKPSAIQQR 16 1 I3L3H2;P38919;E9PBH4;F8WE11;P60842;P60842-2;J3KT12;J3QL43;J3QS69;J3KTB5;J3QR64;Q14240-2;J3KS25;E7EQG2;J3QLN6;J3QKZ9;Q14240;J3KT04;J3KSN7;J3KS93;E7EMV8;J3QQP0 I3L3H2;P60842 EIF4A3;EIF4A2;EIF4A1 Eukaryotic initiation factor 4A-III;Eukaryotic initiation factor 4A-III, N-terminally processed;Eukaryotic initiation factor 4A-I;Eukaryotic initiation factor 4A-II;Eukaryotic initiation factor 4A-II, N-terminally processed 0 ; 194.3 1.2415999999999999e-11 15875800.0 46973.0 36535.0 36188.0 42208.0 48730.0 41413.0 44484.0 45303.0 38474.0 36637.0 False True 54924.60114096044 40161.95334859667 37050.859163754234 39843.22260018228 39181.706311231945 39241.2293765801 40270.15348372968 44113.84425249624 39036.60946434302 43278.99808166755 1.2690820854336233 0.9279778906344132 0.8560932740133954 0.9206133313206105 0.905328405183872 0.9067037389019919 0.9304779516323326 1.0192898682463334 0.9019758126258113 1.0 15.401379480392993 -4.761489903114149 9.877395198585075 0.9262767311823233 1.270588898431611 0.8348126846055134 0.04524877103261458 0.027982749249739487 55.401935385511685 0.011400742455781194 0.0644986300337452 1.7318492939404006e-05 4.761489903114149 0.3443121672492876 GKAS(ph)PFEEDQNR ddPTM_PC-9_AZD4547_30min_R2 2 GKASPFEEDQNR 12 1 Q8TB72-4;A0A0A0MR59;Q8TB72-3;Q8TB72;C9JW01;Q8TB72-2;A0A0C4DG68 Q8TB72-4 PUM2 Pumilio homolog 2 1 GKAS(1)PFEEDQNR;GKAS(1)PFEEDQNR 148.41 0.00071637 80095000.0 77718.0 72736.0 85761.0 103061.0 94344.0 91392.0 91923.0 101476.0 78337.0 91358.0 True False 102430.70736517679 96246.48956999602 84623.75310475813 79301.87872657736 81245.96409598022 85677.24379248037 100103.9689215531 85795.21588650104 82477.73389184476 88159.58422721097 1.1618782944936001 1.0917303026514158 0.959892833508152 0.8995264601316072 0.9215783491740105 0.9718426481194269 1.1354859462989098 0.9731808133915841 0.9355503955109118 1.0 16.42782979952527 -5.088497971936705 3.271709646762462 0.9748949050993346 1.1534130829622313 0.513158362049521 0.060922803422260044 0.22031887548593312 4.342778870128251 0.017664603985883317 0.06586985136463977 8.156465960208343e-06 5.088497971936705 0.1785181778628967 GKAS(ph)PFEEDQNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GKASPFEEDQNR 12 1 Q8TB72-4;A0A0A0MR59;Q8TB72-3;Q8TB72;C9JW01;Q8TB72-2;A0A0C4DG68 Q8TB72-4 PUM2 Pumilio homolog 2 1 GKAS(1)PFEEDQNR;GKAS(1)PFEEDQNR;GKAS(1)PFEEDQNR;GKAS(1)PFEEDQNR 165.78 0.0004731 55715800.0 88871.0 92862.0 96626.0 102610.0 115513.0 93195.0 101305.0 94065.0 86864.0 78721.0 True False 103915.10501773976 102080.72565642188 98929.93029614544 96861.09436610862 92879.05686700894 88307.69013957898 91708.65701531421 91595.89342010595 88134.2216694571 92992.49414490668 1.1174569084663197 1.097730807148299 1.0638485525722825 1.0416012093962512 0.9987801458715477 0.9496216974455212 0.9861941854404731 0.9849815757965964 0.9477562945254578 1.0 16.504826653867703 -5.858245317961937 1.0840570328914003 0.9720484778724812 1.1149075667741988 0.9093319235065088 0.016847829884774894 0.15038187829547395 0.3497081013015642 0.006496955268214609 0.016073461571280933 1.385972719568449e-06 5.858245317961937 0.1428590889017176 GKAS(ph)PFEEDQNR ddPTM_PC-9_Lapatinib_30min_R1 4 GKASPFEEDQNR 12 1 Q8TB72-4;A0A0A0MR59;Q8TB72-3;Q8TB72;C9JW01;Q8TB72-2;A0A0C4DG68 Q8TB72-4 PUM2 Pumilio homolog 2 1 GKAS(1)PFEEDQNR;GKAS(1)PFEEDQNR;GKAS(1)PFEEDQNR;GKAS(1)PFEEDQNR 165.78 0.0040598 188840000.0 318321.0 403302.0 432563.0 389547.0 514763.0 417926.0 391413.0 438819.0 434218.0 347980.0 True False 313781.68416707753 402368.1789978019 396999.33988146594 418195.5858706987 484485.6524029967 400052.27921308955 411678.44994148175 459208.1327275187 385311.79632175126 408127.8793457962 0.7688317805440055 0.9858875106566434 0.9727327143586255 1.0246680195948397 1.1870927641101052 0.980213064234545 1.0086996521810196 1.1251574713876469 0.9440957499384318 1.0 18.63866173935805 -4.131814345291971 1.1696268117134128 1.042170612865677 9.974764211623822e-20 0.5595712547314113 0.06936624743718837 4.407774260542325 1.7282604506320824 0.02054439163609199 8.125468501832593 7.382197411154725e-05 4.131814345291971 -1.042170612865677 GKDCAVIVTQK ddPTM_PC-9_Lapatinib_30min_R1 1 GKDCAVIVTQK 11 1 G3V3U4;G3V3I1;G3V295;G3V5Z7;P60900;P60900-2 G3V3U4 PSMA6 Proteasome subunit alpha type;Proteasome subunit alpha type-6 0 104.59 0.0034525 4404600.0 22941.0 24017.0 21594.0 21370.0 19273.0 20539.0 21601.0 21112.0 22782.0 23433.0 False True 22613.857133135833 23961.390112100085 19818.62467525053 22941.621088230193 18139.400032175883 19660.594848747474 22719.394085495263 22092.940593145224 20216.05125490453 27483.36282749018 0.822819873793478 0.8718507361163516 0.7211135260138904 0.8347457780997194 0.6600138471421694 0.7153635081760084 0.8266599043247442 0.8038659872818331 0.7355741501430628 1.0 14.746270920740313 -10.912528119514786 6.305934295215517 1.0000316193387806 0.7767539770724399 0.5286593403270725 0.06320036204615899 2.8956757375493513e-05 2.8026426501087226e-06 0.06307125903223951 0.015294864170073074 1.2231279219184948e-11 10.912528119514786 -0.22327764226634073 GKDSYETSQLDDQS(ph)AETHSHK ddPTM_PC-9_AZD4547_30min_R2 3 GKDSYETSQLDDQSAETHSHK 21 1 P10451-4;P10451;P10451-3;P10451-5;P10451-2;D6R9C5 P10451-4 SPP1 Osteopontin 1 GKDSYETSQLDDQS(0.578)AET(0.364)HS(0.058)HK;GKDS(0.003)Y(0.001)ET(0.003)S(0.012)QLDDQS(0.625)AET(0.218)HS(0.137)HK;GKDS(0.009)Y(0.002)ET(0.008)S(0.011)QLDDQS(0.798)AET(0.126)HS(0.046)HK 64.68 0.0019164000000000002 30455200.0 100464.0 105298.0 130572.0 169645.0 150438.0 142455.0 118596.0 138274.0 120064.0 133257.0 True False 132409.46221898578 139333.51928538075 128840.52996577077 130535.9662391226 129552.28044890071 133547.26633028933 129150.81424910514 116906.93052041893 126410.33792448591 128591.71299027377 1.0296889211593345 1.0835342032959734 1.0019349378720526 1.0151195843311915 1.007469901724535 1.0385371127328429 1.0043478793915255 0.9091326944937841 0.9830364257924393 1.0 16.972438146550076 -7.534326363599464 24.176788822843648 0.9589987529203085 1.0283249033987567 0.47891980075578666 0.03034055725984773 120.90252770250007 255334.73187348476 0.014093999740724507 0.008147233266682975 2.9219557613942507e-08 7.534326363599464 0.06932615047844826 GKDSYETSQLDDQS(ph)AETHSHK ddPTM_PC-9_Lapatinib_30min_R1 2 GKDSYETSQLDDQSAETHSHK 21 1 P10451-4;P10451;P10451-3;P10451-5;P10451-2;D6R9C5 P10451-4 SPP1 Osteopontin 1 GKDSYETSQLDDQS(0.782)AET(0.092)HS(0.125)HK;GKDSYETS(0.001)QLDDQS(0.905)AET(0.07)HS(0.024)HK 60.826 0.0039821 23028000.0 92536.0 75380.0 83149.0 71828.0 77204.0 67237.0 46598.0 46152.0 86626.0 44563.0 True False 91216.41967097609 75205.46224133327 76312.81018442189 77110.47073118399 72663.01250890405 64361.43024710236 49010.616434234915 48296.39040615944 76869.26766777992 52265.65517353499 1.7452458860051567 1.438907863904746 1.4600947779386741 1.4753564357924533 1.3902631138487551 1.2314287467249072 0.9377212678480249 0.9240559645871346 1.4707414919521204 1.0 15.673575613074794 -6.738924517175203 1.9670668356717214 1.0773139578364617 1.5181631345905522 0.5987059368362373 0.1649423941922824 0.23361834894943465 1.862725330868868 0.06597207205501823 0.06149826656170528 1.8242127332061221e-07 6.738924517175203 0.4408491767540905 GKELSDQATAS(ph)PIVAR ddPTM_PC-9_AZD4547_30min_R2 2 GKELSDQATASPIVAR 16 1 Q5JSH3-2;Q5JSH3;Q5JSH3-4 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 GKELSDQAT(0.027)AS(0.973)PIVAR;GKELS(0.028)DQAT(0.021)AS(0.951)PIVAR 137.86 6.6761e-06 59748000.0 175288.0 134197.0 234730.0 375670.0 346940.0 255160.0 192480.0 292740.0 218379.0 253250.0 True False 231025.9377831028 177573.55588463435 231617.32683014256 289065.0855436421 298773.36962032 239204.80486354735 209610.34711683137 247503.75949598206 229922.06811043574 244383.7945833012 0.9453406604845673 0.7266175573851572 0.9477605797269547 1.1828324625064726 1.2225580265244609 0.9788079658531182 0.8577096835501632 1.0127666603998875 0.9408237092908548 1.0 17.898789095724993 -5.517651241060356 24.926617794734756 1.0303435011163284 0.8362815732951725 0.31752565474172323 0.1121700498744069 253.3071129635349 1207857.323406272 0.03304667511015552 0.05944406909373662 3.0363285203359906e-06 5.517651241060356 -0.19406192782115594 GKELSDQATAS(ph)PIVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GKELSDQATASPIVAR 16 1 Q5JSH3-2;Q5JSH3;Q5JSH3-4 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 GKELSDQAT(0.2)AS(0.8)PIVAR;GKELSDQAT(0.007)AS(0.993)PIVAR 158.44 2.303e-05 38929000.0 128278.0 67867.0 114848.0 194641.0 201295.0 210150.0 157436.0 197132.0 168834.0 141820.0 True False 149992.93179401188 74604.38724262234 117586.41188346522 183735.89580463615 161852.6897582481 199129.3640520685 142522.52234206616 191957.493878619 171302.87784745253 167530.8433534975 0.8953153269665105 0.4453173263457152 0.7018791855261701 1.0967287702178234 0.96610681662201 1.1886131536501414 0.8507240785587006 1.1458039011573538 1.0225154629347617 1.0 17.3540672025849 -5.71042679475926 5.940056202111077 1.0401273508478408 0.6507328353083243 0.593422580721012 0.13532884569564546 0.11710362200867193 9.04778901515318 0.03454688130881287 0.05965750385659653 1.947929367769662e-06 5.71042679475926 -0.38939451553951654 GKELSDQATAS(ph)PIVAR ddPTM_PC-9_Lapatinib_30min_R1 1 GKELSDQATASPIVAR 16 1 Q5JSH3-2;Q5JSH3;Q5JSH3-4 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 GKELSDQAT(0.007)AS(0.993)PIVAR 126.29 1.353e-05 25673000.0 197890.0 109730.0 131250.0 125400.0 93276.0 112830.0 86962.0 79721.0 106010.0 79796.0 True False 195068.05231141887 109475.9269267913 120459.13163965126 134622.33432213674 87789.68906767183 108004.52391957624 91464.46685166607 83425.12869581903 94070.03746521061 93588.63227851359 2.084313527853567 1.1697566708849658 1.2871128544882764 1.4384475020588994 0.9380379532250831 1.1540346438460807 0.9773031683962842 0.8914023708301598 1.0051438425263486 1.0 16.51404568338169 -1.5228787452803376 0.6512612944953252 1.0173220078321463 85.86417165843947 0.7669951478920296 0.16302358640641523 109.53426882941761 0.7034555684036902 0.06954391478979012 13403.020746403645 0.029999999999999995 1.5228787452803376 84.84684965060733 up GKGFSVVADT(ph)PELQR ddPTM_PC-9_AZD4547_30min_R2 1 GKGFSVVADTPELQR 15 1 Q14847;Q14847-2;C9J9W2;Q14847-3 Q14847 LASP1 LIM and SH3 domain protein 1 1 GKGFSVVADT(1)PELQR 60.938 0.035285000000000004 18517000.0 32526.0 25545.0 52367.0 82519.0 60848.0 53701.0 37306.0 57041.0 35350.0 46385.0 True False 42868.59141717164 33801.92169029847 51672.57936401004 63495.51945584109 52400.30551293367 50343.06798078606 40626.16172870181 48226.62412178156 37218.52883154465 44761.0752684952 0.9577203219544734 0.7551633084670273 1.154408803945321 1.4185432113721361 1.1706668170640506 1.1247064034723873 0.907622560115223 1.077423270832941 0.8314931803646969 1.0 15.449957073278696 -7.2536525021807075 24.184530693717996 0.9605866924300794 1.1019276747965527 0.1460742206428539 0.16851095864140117 893.1753518427187 2774035.377635536 0.07338461462599184 0.05572132056946083 5.576317557858879e-08 7.2536525021807075 0.1413409823664733 GKGFSVVADT(ph)PELQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GKGFSVVADTPELQR 15 1 Q14847;Q14847-2;C9J9W2;Q14847-3 Q14847 LASP1 LIM and SH3 domain protein 1 1 GKGFSVVADT(1)PELQR 71.872 0.014988999999999999 9275500.0 29713.0 16256.0 35349.0 51686.0 57098.0 65158.0 37476.0 54555.0 44149.0 36004.0 True False 34742.824041499545 17869.788247838704 36191.854221829024 48790.20098827292 45910.056781422536 61740.9997758966 33926.001977255946 53122.98905580053 44794.59560329784 42531.240192492834 0.8168777558391533 0.42015676399186896 0.8509475401617193 1.1471614927627916 1.0794431710346903 1.4516623427029638 0.7976725302086114 1.2490345641314555 1.05321630407581 1.0 15.37623530348732 -5.566408453733974 3.7787179703069396 1.12009553514633 0.616980529861189 0.5418352635763859 0.18262316746105972 0.14707507410645293 4.408848120536463 0.04782255565705195 0.09207618030771991 2.713885660143987e-06 5.566408453733974 -0.503115005285141 GKGFSVVADT(ph)PELQR ddPTM_PC-9_Lapatinib_30min_R1 1 GKGFSVVADTPELQR 15 1 Q14847;Q14847-2;C9J9W2;Q14847-3 Q14847 LASP1 LIM and SH3 domain protein 1 1 GKGFSVVADT(1)PELQR 90.45299999999999 0.0030381999999999996 11437000.0 226850.0 89139.0 99395.0 83562.0 60253.0 52702.0 37402.0 34692.0 65639.0 33150.0 True False 223615.07740080496 88932.60412218394 91223.12677579536 89707.4282346603 56709.0370019558 50448.05831436242 39338.492550608484 36303.91696937258 58246.04461068728 38879.93333040157 5.751426462090988 2.287365139400701 2.34627786011312 2.3072937772893494 1.4585682675955887 1.2975345890039203 1.011794238850928 0.9337443215465929 1.4981004240854157 1.0 15.246738124625306 -2.1431894834602883 0.7011925308425773 1.2398790219878326 199.999999378053 0.9051752474029625 0.41907530058896775 31.666204167420126 0.4373055742638484 0.17015306460126112 9514.963616954847 0.007191351495929699 2.1431894834602883 198.76012035606516 up GKGGVT(ph)GSPEASISGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GKGGVTGSPEASISGSK 17 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GKGGVT(0.752)GS(0.247)PEAS(0.001)ISGSK;GKGGVT(0.5)GS(0.5)PEASISGSK 124.91 0.00040757 149375000.0 83154.0 59959.0 75932.0 91540.0 105525.0 94050.0 95952.0 83871.0 77119.0 76673.0 True False 97230.329833637 65911.3332647737 77742.50685371376 86411.3105766843 84848.133767551 89117.85243443747 86862.73192767818 81669.47511867019 78246.71948018578 90573.20795686598 1.0734999016479727 0.7277133575324273 0.8583388907980091 0.9540493543944725 0.9367906435196437 0.9839317215845816 0.9590334038852322 0.9016957327774451 0.8639057978099828 1.0 16.46679673595731 -5.760978147596537 24.999993367903553 0.9408196481486305 0.8706369705257067 0.07244338694620056 0.08663842079742026 26.520356917757233 1437298.5986580523 0.023248758678622854 0.03732044258810436 1.733891239796759e-06 5.760978147596537 -0.07018267762292385 GKGGVTGS(ph)PEASISGSK ddPTM_PC-9_AZD4547_30min_R2 5 GKGGVTGSPEASISGSK 17 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GKGGVT(0.01)GS(0.977)PEAS(0.012)ISGSK;GKGGVTGS(1)PEASISGSK;GKGGVT(0.005)GS(0.994)PEAS(0.001)ISGSK;GKGGVT(0.007)GS(0.992)PEAS(0.001)ISGSK;GKGGVT(0.019)GS(0.981)PEASISGSK 231.42 5.1549e-29 1708800000.0 329822.0 289892.0 414915.0 509238.0 464372.0 418545.0 361476.0 476119.0 364594.0 412314.0 True False 434698.53527622076 383593.91985296586 409412.9559993549 391841.0467486711 399901.96344418824 392373.31498515926 393646.6637282004 402545.7486761888 383865.6945065966 397879.01235861395 1.0925394951076757 0.9640968936236005 1.0289885700991568 0.9848246189861838 1.0050843372551428 0.9861623830299138 0.9893627245998117 1.0117290336323863 0.9647799521544329 1.0 18.601970275039918 -4.750501400596022 24.999106622757957 0.9941011634412654 1.0925397054445198 0.7120975632395392 0.019012689720678273 240.72328428706464 550145.122055497 0.004311504619499492 0.06275948259236971 1.7762275399604445e-05 4.750501400596022 0.09843854200325441 GKGGVTGS(ph)PEASISGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GKGGVTGSPEASISGSK 17 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GKGGVT(0.001)GS(0.982)PEAS(0.017)IS(0.001)GSK;GKGGVT(0.104)GS(0.894)PEAS(0.001)ISGSK;GKGGVT(0.014)GS(0.78)PEAS(0.179)IS(0.018)GS(0.009)K 194.15 2.2613000000000003e-11 748400000.0 198815.0 165538.0 193657.0 210734.0 274329.0 224360.0 221374.0 190202.0 181397.0 173397.0 True False 232470.45272475758 181971.51863747078 198274.5173282619 198927.25718884595 220576.20173720422 212594.16663679294 200403.85211103235 185209.39903567696 184049.5879555919 204832.50349010283 1.1349295095443197 0.8883918105617615 0.9679836644570533 0.9711703650512565 1.0768613280551058 1.0378927319367806 0.9783791570985487 0.9041992646671234 0.8985370232731881 1.0 17.64408513949762 -7.584609820973188 5.106364628820848 0.9269871529610987 1.006407210051279 0.20727874133757151 0.06768727429635235 0.322496325910177 16.792872670780756 0.03292127809950388 0.01868788093517504 2.602496649273724e-08 7.584609820973188 0.07942005709018041 GKGGVTGS(ph)PEASISGSK ddPTM_PC-9_Lapatinib_30min_R1 4 GKGGVTGSPEASISGSK 17 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GKGGVT(0.001)GS(0.998)PEAS(0.001)ISGSK;GKGGVT(0.001)GS(0.999)PEASISGSK;GKGGVT(0.219)GS(0.781)PEASISGSK;GKGGVT(0.004)GS(0.996)PEASISGSK 224.59 3.1447e-28 1101521000.0 579270.0 547060.0 575990.0 471319.0 499300.0 473150.0 401247.0 398189.0 515180.0 346211.0 True False 571009.5035748926 545793.3161812657 528634.3255856968 505981.3715340928 469932.1556615694 452914.47746652114 422021.6063433511 416690.31460041157 457155.0033140955 406053.11005284043 1.406243393876693 1.3441426815084379 1.30188468576661 1.2460965302500664 1.1573169716651506 1.1154069904983182 1.0393261272852525 1.026196584348749 1.1258502693270964 1.0 18.631308912681604 -6.043990446291181 0.6910047539885144 1.0370296842209232 1.4203728767179815 0.9421196842748909 0.03233820798936333 0.1967858981938792 0.186088171779081 0.018841002188115588 0.046338651143697104 9.03669352627663e-07 6.043990446291181 0.3833431924970583 GKGGVTGSPEASISGS(ph)KGDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GKGGVTGSPEASISGSKGDLK 21 2 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GKGGVTGSPEASIS(0.159)GS(0.841)KGDLK 100.44 0.00056037 6498000.0 6373.4 7231.9 8214.0 15462.0 19546.0 13204.0 15619.0 11776.0 13828.0 11016.0 True False 7452.290739612062 7949.835238037944 8409.852911768474 14595.71426848036 15716.101612135011 12511.55899568646 14139.455248232494 11466.892477703359 14030.208339994173 13013.113597391974 0.5726754541745962 0.6109095397147084 0.6462598554010883 1.121615834615135 1.2077126273057939 0.9614577558282414 1.0865543547599752 0.8811797723798783 1.0781592149327 1.0 13.667678570973761 -5.725944877207793 7.2712428322161005 1.0477923523007409 0.6066570117064363 0.8459779737546175 0.08569587269080775 0.07484315180580384 11.700358044555342 0.024438868811352897 0.04184117233155165 1.8795553640776594e-06 5.725944877207793 -0.4411353405943046 GKHT(ph)RY(ph)QECNPSLT(ph)QGS(ph)S(ph)EIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GKHTRYQECNPSLTQGSSEIK 21 2 D6RGC4 D6RGC4 MARCH1 5 GKHT(0.709)RY(0.684)QECNPS(0.658)LT(0.969)QGS(0.99)S(0.99)EIK 47.751999999999995 0.021481 4394300.0 5461.3 4439.0 4598.9 6127.4 6041.7 5813.1 7485.8 6329.7 5361.0 5123.4 True False 6385.79022440822 4879.674583671017 4708.5552174253735 5784.101643298826 4857.872255706343 5508.250802622309 6776.690831501298 6163.552081871515 5439.394482984432 6052.231863187915 1.05511328196944 0.8062603505578069 0.7779865880659136 0.9556972987898954 0.802657988907176 0.9101189325091268 1.1197011259135379 1.018393250820527 0.8987419196658667 1.0 12.563251543443394 -7.018052245697237 23.67808095442237 1.011337332332296 0.8722933777510766 0.3123655394524436 0.0911489494566936 438.34972370916404 574956.6035047293 0.03397029638651451 0.026896037286299856 9.592852224049813e-08 7.018052245697237 -0.13904395458121943 GKIEVLDS(ph)PASK ddPTM_PC-9_AZD4547_30min_R2 2 GKIEVLDSPASK 12 1 Q8N5I9 Q8N5I9 C12orf45 Uncharacterized protein C12orf45 1 GKIEVLDS(0.99)PAS(0.01)K;GKIEVLDS(0.616)PAS(0.384)K 93.76799999999999 0.0024244 81817000.0 139793.0 121481.0 189734.0 212650.0 246480.0 187893.0 168068.0 206403.0 179366.0 216644.0 True False 184244.2661249669 160747.35755956752 187218.00319000648 163626.82790974944 212260.50655449444 176144.02100731494 183025.72640914237 174508.15901909294 188846.92057705356 209059.35950130137 0.8813012082523863 0.7689077300486367 0.8955255753036069 0.7826811882523292 1.0153121441720152 0.8425550591348601 0.8754725301260815 0.8347301906758527 0.9033172254403564 1.0 17.673553108126676 -14.52287874524717 0.17278991219523968 1.525486155970194 0.8350849096439504 0.29324513150844933 0.06445402133817965 171.4091846100314 1.6216599190733727 30.93738741070108 0.21733531407761006 3.0000000002291186e-15 14.52287874524717 -0.6904012463262436 GKIEVLDS(ph)PASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GKIEVLDSPASK 12 1 Q8N5I9 Q8N5I9 C12orf45 Uncharacterized protein C12orf45 1 GKIEVLDS(0.775)PAS(0.225)K;GKIEVLDS(0.992)PAS(0.008)K;GKIEVLDS(0.978)PAS(0.022)K;GKIEVLDS(0.923)PAS(0.077)K 139.21 0.00034622 82327600.0 339084.0 314880.0 361515.0 455992.0 502507.0 483089.0 422828.0 469793.0 425027.0 328321.0 True False 396484.2239857237 346139.205430576 370134.8886532731 430444.24658601143 404044.3606266822 457754.9624104191 382774.67083037685 457461.4315368293 431242.21580291376 387842.99831239396 1.0222802157340212 0.8924724874155727 0.9543420669286968 1.109841478275969 1.0417729916094516 1.1802584148798103 0.9869320124275268 1.1795015857637323 1.1118989325045472 1.0 18.565113231500014 -5.756045902169005 24.771557544198057 1.0924617238389283 0.9499756253573712 0.4322771062420383 0.06839059020236107 97.25026213610991 446651.0437842936 0.01764615437401769 0.029460170268542574 1.7536951376057902e-06 5.756045902169005 -0.14248609848155702 GKIEVLDS(ph)PASK ddPTM_PC-9_Lapatinib_30min_R1 3 GKIEVLDSPASK 12 1 Q8N5I9 Q8N5I9 C12orf45 Uncharacterized protein C12orf45 1 GKIEVLDS(0.86)PAS(0.14)K;GKIEVLDS(0.998)PAS(0.002)K;GKIEVLDS(0.941)PAS(0.059)K 88.133 0.0038694000000000003 55387000.0 424820.0 340140.0 378556.0 375583.0 363161.0 355592.0 269081.0 286273.0 360985.0 314721.0 True False 418761.9888975525 339352.42672813905 347432.5869484185 403204.6267281601 341800.58398199663 340384.159085438 283012.69755655515 299574.2886709676 320327.0679594288 369120.10551062744 1.1344870751980638 0.9193550328522234 0.9412453609585769 1.0923399205534505 0.9259874465769401 0.9221501457217098 0.7667225202080109 0.8115902769819253 0.8678125715105653 1.0 18.493730795955578 -6.730703021467507 2.266541234238177 0.8481363955615498 1.0076771926826795 0.3912430631649747 0.08449090520085464 0.29329660090208903 3.0929896986196024 0.03176632779032644 0.029891525859927943 1.8590752903143714e-07 6.730703021467507 0.15954079712112967 GKLEAIIT(ph)PPPAKK ddPTM_PC-9_AZD4547_30min_R2 1 GKLEAIITPPPAKK 14 2 D6RCF2;O75367-2;O75367-3;O75367 D6RCF2 H2AFY Histone H2A;Core histone macro-H2A.1 1 GKLEAIIT(1)PPPAKK 52.576 0.042076 66278000.0 53755.0 56158.0 58365.0 73429.0 62145.0 61144.0 50266.0 65286.0 45595.0 59140.0 True False 70847.97182654071 74309.9752704554 57591.04196498643 56501.07851674097 53517.239450783294 57320.65601417444 54739.5766218551 55197.54882303305 48005.05861596265 57069.52660081502 1.2414326181834654 1.3020955262207163 1.0091382458421156 0.9900393762147323 0.9377550969560523 1.0044004117138732 0.9591734833327556 0.9671982949696444 0.8411679836026024 1.0 15.800432975269452 -5.3345869128357855 3.998856962411407 0.959658933745248 1.2740044542138989 0.8750319703293833 0.04679514521246307 0.06609775781049322 2.0237491364959213 0.012414793763125532 0.028863985911178 4.628210328200979e-06 5.3345869128357855 0.31434552046865083 GKLEAIIT(ph)PPPAKK ddPTM_PC-9_Lapatinib_30min_R1 1 GKLEAIITPPPAKK 14 2 D6RCF2;O75367-2;O75367-3;O75367 D6RCF2 H2AFY Histone H2A;Core histone macro-H2A.1 1 GKLEAIIT(1)PPPAKK 52.453 0.042429 59813000.0 95938.0 64749.0 66772.0 51278.0 67087.0 57324.0 52080.0 44012.0 63659.0 40687.0 True False 94569.90652712547 64599.077668666665 61282.263907373715 55049.155178393456 63141.07455811677 54872.386148770674 54776.44757060292 46056.95819370532 56489.053061011655 47719.693737980335 1.9817794105383544 1.353719452253147 1.284213269344578 1.1535940586848228 1.3231659638222382 1.1498897383974087 1.1478792775026987 0.9651561983317669 1.1837681392337132 1.0 15.542297163485465 -1.6670497910679805 0.8322997759925059 1.1267291384551106 199.9999999999941 0.8742334011161742 0.09584120596292217 150.68556403807483 0.5961497997582662 0.033786634278809166 56461.257860097474 0.021525349363839076 1.6670497910679805 198.87327086153897 GKLS(ph)AEENPDDSEVPSSSGINSTK ddPTM_PC-9_AZD4547_30min_R2 3 GKLSAEENPDDSEVPSSSGINSTK 24 1 A0A494C1S7;Q9Y5Q9-2;Q9Y5Q9 A0A494C1S7 GTF3C3 General transcription factor 3C polypeptide 3 1 GKLS(1)AEENPDDSEVPSSSGINSTK;GKLS(1)AEENPDDSEVPSSSGINSTK;GKLS(1)AEENPDDSEVPSSSGINSTK 139.64 1.4134999999999999e-06 210744000.0 201467.0 164910.0 217414.0 260015.0 246094.0 201732.0 207637.0 245089.0 194721.0 203589.0 True False 265529.3152260748 218213.9325091846 214530.94830421606 200072.55894170442 211928.09599164984 189117.66614960463 226116.2907538324 207216.1266349352 205013.55452919987 196461.41107766866 1.3515596460879584 1.1107215982629604 1.0919749946181738 1.0183809524945748 1.078726325079008 0.9626199115247077 1.1509450609842156 1.0547421272110014 1.0435309071874181 1.0 17.58388644079311 -4.339843992298134 1.449060351652124 1.0501461781797645 1.9119061201177874 0.7749399518040998 0.04870690044508307 1.6596464481453863 1.3502689868020483 0.013281766512370716 2.834084536214636 4.572524147902185e-05 4.339843992298134 0.8617599419380229 GKLS(ph)AEENPDDSEVPSSSGINSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GKLSAEENPDDSEVPSSSGINSTK 24 1 A0A494C1S7;Q9Y5Q9-2;Q9Y5Q9 A0A494C1S7 GTF3C3 General transcription factor 3C polypeptide 3 1 GKLS(0.999)AEENPDDS(0.001)EVPSSSGINSTK;GKLS(0.999)AEENPDDS(0.001)EVPSSSGINSTK;GKLS(0.999)AEENPDDS(0.001)EVPSSSGINSTK;GKLS(1)AEENPDDSEVPSSSGINSTK;GKLS(1)AEENPDDSEVPSSSGINSTK 145.03 6.0865e-07 188446900.0 288439.0 289125.0 239059.0 349656.0 340846.0 311967.0 369723.0 316051.0 314006.0 261974.0 True False 337266.0257700706 317827.41923944117 244759.07319630674 330065.90792004735 274059.67308348423 295606.90133348387 334700.16087728145 307754.9961337142 318597.74370901135 309467.8124149566 1.0898258631105717 1.0270128475050433 0.7909031678813699 1.0665597347405917 0.8855837734620535 0.9552104919302978 1.0815346457695298 0.9944652845545509 1.0295020384278695 1.0 18.239429837723932 -7.226738266841961 24.64248455426342 1.025914294355186 0.9643339528511672 0.09761886436605782 0.08441393773892056 1213.107295880945 861471.3453136549 0.03215656741448554 0.024906662642174667 5.932827663542701e-08 7.226738266841961 -0.06158034150401881 GKLS(ph)AEENPDDSEVPSSSGINSTK ddPTM_PC-9_Lapatinib_30min_R1 5 GKLSAEENPDDSEVPSSSGINSTK 24 1 A0A494C1S7;Q9Y5Q9-2;Q9Y5Q9 A0A494C1S7 GTF3C3 General transcription factor 3C polypeptide 3 1 GKLS(1)AEENPDDSEVPSSSGINSTK;GKLS(0.991)AEENPDDS(0.009)EVPSSSGINSTK;GKLS(0.964)AEENPDDS(0.036)EVPSSSGINSTK;GKLS(1)AEENPDDSEVPSSSGINSTK;GKLS(0.996)AEENPDDS(0.004)EVPSSSGINSTK 123.03 2.0099e-09 319147000.0 545111.0 450582.0 455721.0 408894.0 437324.0 443240.0 434697.0 428957.0 472067.0 317409.0 True False 537337.6171788855 449538.70506267506 418253.37851393106 438965.4287903974 411601.4621320645 424283.65844290494 457203.48367124377 448887.9082045184 418897.84337411186 372272.7227290929 1.4433977682805201 1.2075520918297566 1.1235133625900893 1.1791501283585517 1.1056449667186377 1.1397119169315584 1.2281412409685357 1.205803919539867 1.1252445258497992 1.0 18.50600038494489 -4.765847719087081 3.018353552817278 1.1495340517138308 1.4974501708986299 0.6969640937924123 0.05997208533185803 0.22292696426674463 2.8631214703835886 0.014793337197284234 0.1932102603848715 1.7145583944637727e-05 4.765847719087081 0.34791611918479903 GKPIFPVYPLVGS(ph)SSPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GKPIFPVYPLVGSSSPTR 18 1 A6NEL2 A6NEL2 SOWAHB Ankyrin repeat domain-containing protein SOWAHB 1 GKPIFPVYPLVGS(0.296)S(0.296)S(0.296)PT(0.111)R 83.727 0.00098577 3142000.0 39006.0 32304.0 35536.0 43981.0 50056.0 47095.0 41639.0 34377.0 39900.0 31093.0 True False 45608.94539638311 35510.927630301514 36383.31301103049 41516.88715832586 40247.88613000257 44625.25529399076 37694.652479746 33474.64017544231 40483.462016616075 36729.91476794744 1.2417383945628975 0.96681214357977 0.9905635022812682 1.1303289817202569 1.0957794589037573 1.2149566797506766 1.0262657214941442 0.9113726614104245 1.1021931924531496 1.0 15.164667927837854 -7.506715416602674 24.760022160773897 0.9978335879604238 1.0977185021993552 0.2119224894484194 0.09085345556493614 1033.3107298218608 1582898.9346341463 0.03933076112016746 0.025664808075200107 3.113756042985687e-08 7.506715416602674 0.09988491423893142 GKPPPLLPSVLGPAGGDREALGLGPPAAQLT(ph)PPPAPVGLR ddPTM_PC-9_AZD4547_30min_R2 1 GKPPPLLPSVLGPAGGDREALGLGPPAAQLTPPPAPVGLR 40 2 A0A087WZ13;Q8IY67-2;E9PAU2;Q8IY67 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 GKPPPLLPS(0.001)VLGPAGGDREALGLGPPAAQLT(0.999)PPPAPVGLR 46.696000000000005 0.0017854 1247200.0 2522.9 2625.1 3224.4 6912.9 4300.5 3574.3 810.84 2585.5 786.19 4255.2 True False 3325.129720420045 3473.6122383715983 3181.642349214467 5319.237708240331 3703.449807033448 3350.798455964013 883.0031891947831 2185.970383879423 827.7463983613044 4106.226743182077 0.8097774254529526 0.8459377563937833 0.7748335754953674 1.2954076920063706 0.9019106928721375 0.8160285988901205 0.21504004635421303 0.5323550112055985 0.20158321742355878 1.0 12.003597578994247 -7.091919126347676 5.411653411040479 0.45013994327323326 0.9271324568196001 0.4129204391852963 0.24637771915989898 0.20439874074513983 9.364179182587725 0.0918238352469483 0.07118598831262471 8.092465818052904e-08 7.091919126347676 0.47699251354636685 GKS(ph)EEELEASK ddPTM_PC-9_Lapatinib_30min_R1 2 GKSEEELEASK 11 1 Q7RTP6;A0A5F9ZHV5;J3QR21 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 GKS(0.999)EEELEAS(0.001)K;GKS(1)EEELEASK 122.97 0.0028844 0.0 21176.2 15928.3 20526.3 21029.0 19667.7 13957.3 17234.9 17767.6 17154.6 17988.1 True False 20874.223504760535 15891.418999981843 18838.706847809335 22575.542810687555 18510.884554185934 13360.378815055426 18127.238790986634 18593.147559812744 15222.468302053601 21097.31911736339 0.9894254046515681 0.7532435240505502 0.8929431622572754 1.0700668973674274 0.8774045863936909 0.6332737700336365 0.8592200122748137 0.8813038024584993 0.7215356708296314 1.0 14.364772063704045 -6.531693105222994 24.998480452894615 0.8076223346974291 0.919418463972242 0.1518876077457969 0.11782179565475202 367.3542244135713 1041848.5041475986 0.038668886396118686 0.038723339132210405 2.9397262796600384e-07 6.531693105222994 0.11179612927481297 GKS(ph)SPICSTTGDDKLCADSACQQNTVTSSGDLVAK ddPTM_PC-9_AZD4547_30min_R2 1 GKSSPICSTTGDDKLCADSACQQNTVTSSGDLVAK 35 2 Q12802-2;Q12802;Q12802-4;H0YMW2 Q12802-2 AKAP13 A-kinase anchor protein 13 1 GKS(0.503)S(0.398)PICS(0.033)T(0.033)T(0.033)GDDKLCADS(0.001)ACQQNTVTSSGDLVAK 66.884 5.4973e-06 8204000.0 21897.0 22324.0 25032.0 29898.0 28459.0 30577.0 23319.0 29238.0 21859.0 29414.0 True False 28859.790514105873 29539.796430386486 24700.059324381753 23005.47801949535 24507.959088097858 28665.015356296808 25394.345825111173 24719.938922400535 23014.422113967044 28384.224812924804 1.0167545777387064 1.040711755387996 0.870203765900788 0.8105022480310883 0.8634359137734182 1.009892485886884 0.8946640604941875 0.8709041407797852 0.8108173559662404 1.0 14.792801720992415 -5.260215235135234 24.99055367104802 0.8871663823672089 1.0287331789289966 0.42345557276503676 0.06399859514943063 96.92112992916073 1978557.785295956 0.017004510522823684 0.040177705652585945 5.492685904086614e-06 5.260215235135234 0.14156679656178772 GKS(ph)SPICSTTGDDKLCADSACQQNTVTSSGDLVAK ddPTM_PC-9_Lapatinib_30min_R1 1 GKSSPICSTTGDDKLCADSACQQNTVTSSGDLVAK 35 2 Q12802-2;Q12802;Q12802-4;H0YMW2 Q12802-2 AKAP13 A-kinase anchor protein 13 1 GKS(0.27)S(0.241)PICS(0.145)T(0.145)T(0.145)GDDKLCADS(0.035)ACQQNT(0.012)VT(0.004)S(0.001)S(0.001)GDLVAK 43.9 0.0049815 9621800.0 50630.0 44249.0 53914.0 42523.0 51413.0 52079.0 43172.0 40940.0 47253.0 41112.0 True False 49908.00691559514 44146.544159150464 49481.39903405843 45650.28327256964 48388.98842184706 49851.702572078524 45407.23491778165 42842.22185881796 41930.86954385057 48218.154421703446 1.0350459803814283 0.9155585627159485 1.0261985268309313 0.9467447234359933 1.003542939421728 1.0338782802860618 0.9417041249787741 0.8885081225658499 0.8696075170595308 1.0 15.557288811543149 -7.496944479461828 6.810949260747463 0.9101629486634937 0.9897629650023191 0.32899772729678856 0.048020462764511905 0.19067910749760847 34.61467340523232 0.01999800061403143 0.012836297947855114 3.184604617989793e-08 7.496944479461828 0.07960001633882541 GKSS(ph)PICSTTGDDKLCADSACQQNTVTSSGDLVAK ddPTM_PC-9_AZD4547_30min_R2 1 GKSSPICSTTGDDKLCADSACQQNTVTSSGDLVAK 35 2 Q12802-2;Q12802;Q12802-4;H0YMW2 Q12802-2 AKAP13 A-kinase anchor protein 13 1 GKS(0.217)S(0.563)PICS(0.072)T(0.072)T(0.072)GDDKLCADS(0.003)ACQQNT(0.002)VTSSGDLVAK 48.847 0.0021748 14181000.0 35889.0 29904.0 36507.0 43599.0 43115.0 44600.0 30862.0 41292.0 33753.0 41892.0 True False 47300.95546242618 39569.88319540755 36022.893326749945 33547.92414783522 37129.22646907267 41811.15494949922 33608.65821238395 34911.27019576452 35537.11467188479 40425.3738309324 1.1700808423009008 0.9788377804716736 0.8910961090280927 0.8298729478208375 0.9184634043053027 1.034279982774246 0.8313753226610241 0.8635979556248744 0.8790794321533955 1.0 15.302973494535674 -4.79153831378861 2.4820781399535345 0.9011867926706068 1.226492513023986 0.61349038815721 0.06317650812663261 0.3454975869490063 2.737268575241522 0.016875024157487827 0.2408458468086143 1.616075648398037e-05 4.79153831378861 0.32530572035337935 GKSS(ph)PICSTTGDDKLCADSACQQNTVTSSGDLVAK ddPTM_PC-9_Lapatinib_30min_R1 1 GKSSPICSTTGDDKLCADSACQQNTVTSSGDLVAK 35 2 Q12802-2;Q12802;Q12802-4;H0YMW2 Q12802-2 AKAP13 A-kinase anchor protein 13 1 GKS(0.106)S(0.492)PICS(0.125)T(0.125)T(0.125)GDDKLCADS(0.028)ACQQNTVTSSGDLVAK 67.19800000000001 5.2557e-06 8424400.0 16570.0 18685.0 18359.0 18130.0 21081.0 18861.0 18130.0 14918.0 18180.0 15100.0 True False 16333.70876143415 18641.736030502972 16849.5938877894 19463.340679907044 19841.057026840645 18054.358997138443 19068.682689228695 15611.144740836506 16132.376956112914 17710.014880514736 0.9222865633729731 1.0526098456875579 0.9514161338355506 1.0990019382378604 1.1203297772872323 1.0194434685090281 1.0767174854386383 0.8814868223522787 0.910918317401438 1.0 14.112277803837797 -7.761081103031332 24.9999998783858 0.9221519183923408 1.0372391107733916 0.35116649402428557 0.06422620287694744 9.847756376966467 687335.3422489769 0.032649609139365814 0.017336201677114665 1.733480245929567e-08 7.761081103031332 0.1150871923810508 GKTLMMFVTVSGS(ph)PTEK ddPTM_PC-9_Lapatinib_30min_R1 1 GKTLMMFVTVSGSPTEK 17 1 Q14696 Q14696 MESDC2 LDLR chaperone MESD 1 GKTLMMFVT(0.032)VS(0.038)GS(0.465)PT(0.465)EK 54.7 0.026702999999999998 7930200.0 27887.0 24302.0 19298.0 18544.0 29304.0 16536.0 20393.0 20218.0 18271.0 22464.0 True False 27489.326266150525 24245.730212110444 17711.392932434224 19907.78762097056 27580.396333880675 15828.79382729872 21448.849756284653 21157.402089437754 16213.127577840429 26346.872468601523 1.0433620270834993 0.9202507903359276 0.6722389138802528 0.7556034457105054 1.0468186069048304 0.6007845464831714 0.8140947196615457 0.8030327741803799 0.6153719989787089 1.0 14.685344095042554 -6.767703556246841 24.999980087992714 0.757311274419296 0.8701619139787776 0.1334628696518897 0.1499573309065998 349.80127994394826 1396028.7667746337 0.052381430967360754 0.04733486469401136 1.7072473361500145e-07 6.767703556246841 0.1128506395594816 GKTPPVAVT(ph)SPITHTAQSALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GKTPPVAVTSPITHTAQSALK 21 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 GKTPPVAVT(0.454)S(0.454)PIT(0.084)HT(0.007)AQSALK 66.64399999999999 0.002451 3835400.0 19890.0 15132.0 17821.0 24546.0 35265.0 39096.0 30324.0 28972.0 35001.0 29197.0 True False 23256.98415459313 16634.20495609592 18245.92022651885 23170.767199205722 28355.07640192068 37045.73693542547 27451.491193251957 28211.51569837142 35512.82340961351 34490.184976675184 0.6743073187436143 0.48228807608150553 0.5290177550180752 0.6718075653950685 0.8221201603034742 1.0740950493735693 0.7959218314374564 0.8179577963252483 1.0296501289752407 1.0 15.073898245785628 -6.22075187347067 2.367076597201206 0.9239606212316964 0.5575945786222375 0.7541471484478098 0.09592109285987892 0.1506313224487919 1.6594106782918663 0.03171336000690693 0.04161207400622599 6.015173056826387e-07 6.22075187347067 -0.36636604260945893 GKTPPVAVTSPIT(ph)HTAQSALK ddPTM_PC-9_AZD4547_30min_R2 1 GKTPPVAVTSPITHTAQSALK 21 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 GKTPPVAVT(0.115)S(0.115)PIT(0.624)HT(0.14)AQS(0.006)ALK 50.883 0.024705 6456200.0 19579.0 23284.0 36361.0 56102.0 48874.0 42782.0 30280.0 54900.0 34303.0 47560.0 True False 25804.71473150107 30810.09765656331 35878.82938214467 43168.55066725961 42088.68872664866 40106.83477689407 32974.861339867355 46416.46647649598 36116.18654903756 45894.93887613735 0.562256217426144 0.6713179799566688 0.7817600428442784 0.9405950138372382 0.9170660154976759 0.8738836080626584 0.7184857883537205 1.011363510076049 0.7869317932094652 1.0 15.486047446894784 -5.238380027493881 1.8855895990655278 0.8856536711029228 0.568119384843896 0.6243173318069614 0.08600305866343547 0.26284158066526275 1.6310815369031835 0.023667600270224926 0.10465668020739768 5.775904082395211e-06 5.238380027493881 -0.3175342862590268 GKTPPVAVTSPIT(ph)HTAQSALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GKTPPVAVTSPITHTAQSALK 21 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 GKT(0.002)PPVAVT(0.153)S(0.153)PIT(0.631)HT(0.054)AQS(0.007)ALK 54.511 0.011590000000000001 7263000.0 15134.0 12079.0 15030.0 18275.0 22897.0 26318.0 25530.0 21107.0 28559.0 25371.0 True False 17695.88728987493 13278.123292670009 15388.372201592425 17251.110998349403 18410.497217489792 24937.837749808878 23111.613578806293 20552.963614715103 28976.62134668017 29970.561463274487 0.5904423015751381 0.4430388569443665 0.513449580197192 0.5756018624972601 0.6142860299781091 0.8320777633868275 0.7711438308263576 0.6857717243602667 0.9668361195764625 1.0 14.871258490851531 -7.1539798771057415 0.39375038572707116 1.0030824371567564 0.44130191861144424 0.8082357131690409 0.07828158131407098 0.5655943080282699 0.20301361838131105 0.08896228788002915 0.11438844068653096 7.014878008771854e-08 7.1539798771057415 -0.5617805185453122 GKYS(ph)IK ddPTM_PC-9_AZD4547_30min_R2 1 GKYSIK 6 1 Q5PSV4;Q5PSV4-2 Q5PSV4 BRMS1L Breast cancer metastasis-suppressor 1-like protein 1 GKY(0.339)S(0.661)IK 103.71 0.016875 3438800.0 11192.0 14859.0 12164.0 19988.0 13763.0 15362.0 12529.0 16815.0 13841.0 12481.0 True False 14750.823191938307 19661.881166417894 12002.697412183594 15380.075411521597 11852.245016672783 14401.411711529301 13644.056728110902 14216.628120260104 14572.607003038469 12044.043988920743 1.2247400628482856 1.6324982858336254 0.9965670519988815 1.276985987901543 0.9840752016163015 1.195728920018649 1.1328468030058676 1.1803865988315811 1.2099430238251985 1.0 13.556032261944365 -5.2696007554963975 24.970947618011202 1.1321294386672338 1.4286191814000715 0.46178412912150835 0.13202325062803152 434.66247633223753 1329917.5636549152 0.031486373520078825 0.06738209955453894 5.3752571370902555e-06 5.2696007554963975 0.2964897427328377 GKYS(ph)IK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GKYSIK 6 1 Q5PSV4;Q5PSV4-2 Q5PSV4 BRMS1L Breast cancer metastasis-suppressor 1-like protein 1 GKY(0.334)S(0.666)IK 77.72 0.026824 3728400.0 15562.0 10875.0 12762.0 16007.0 17282.0 14129.0 16857.0 15744.0 15630.0 13767.0 True False 18196.33923648961 11954.598129628816 13066.294480154518 15110.179685394198 13895.716159875026 13388.050367317026 15260.182925888677 15330.73668214689 15858.559180945102 16262.848120487972 1.1188900678206435 0.735086378539586 0.8034444141240901 0.929122597311744 0.8544454241301788 0.8232291335519963 0.9383462732252824 0.9426846127175715 0.9751403360255486 1.0 13.989292318972227 -7.461840348449562 4.249673963535042 0.9655694732020922 0.8689172430454866 0.16442443809154494 0.09619275094342508 0.39729976356065133 14.352811401668335 0.04252328546244072 0.026834227379687412 3.4527064139158046e-08 7.461840348449562 -0.09665223015660562 GKYS(ph)IK ddPTM_PC-9_Lapatinib_30min_R1 1 GKYSIK 6 1 Q5PSV4;Q5PSV4-2 Q5PSV4 BRMS1L Breast cancer metastasis-suppressor 1-like protein 1 GKY(0.348)S(0.652)IK 62.338 0.041077999999999996 5404900.0 35356.0 25644.0 28909.0 30769.0 29374.0 30851.0 27055.0 26019.0 26699.0 19104.0 True False 34851.816956503695 25584.622893562664 26532.213611967098 33031.85490237505 27646.27907150598 29531.57464719355 28455.775518868304 27227.937727029435 23691.87746706594 22406.10094552011 1.5554610345300615 1.1418596638375884 1.1841513022046777 1.4742348516009638 1.2338728250277562 1.318014888846518 1.270001219224078 1.215201957414791 1.0573851079521674 1.0 14.451603996002799 -8.18900976818665 1.5333020495865826 0.9958620845913839 1.3070417623407098 0.48015171167082926 0.11747459957770233 0.3427178724838828 1.4830100580231678 0.10631263168729672 0.03299002715717698 6.471280603281637e-09 8.18900976818665 0.31117967774932587 GLAAGSAET(ph)LPANFR ddPTM_PC-9_AZD4547_30min_R2 2 GLAAGSAETLPANFR 15 0 A0A2R8Y7R9;Q13136-2;Q13136 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 GLAAGS(0.014)AET(0.986)LPANFR;GLAAGS(0.023)AET(0.977)LPANFR 111.81 0.00093886 2373300.0 18153.5 14059.1 26719.7 31299.0 25186.4 16977.4 23845.0 18947.1 18208.0 19140.1 True False 23925.93538374301 18603.429134314938 26365.37931965815 24083.499114729577 21689.703108909947 15915.800494162062 25967.15880611418 16019.261056044017 19170.437707631267 18470.010924793023 1.2953936779553434 1.007223504634901 1.4274696115239902 1.3039244650581852 1.1743199934871182 0.8617103995752193 1.4059092283078967 0.8673119426551466 1.0379223805383913 1.0 14.172897099207107 -6.531870833217094 24.910791488378454 1.0459896079853623 1.2509357275059831 0.2765940794694156 0.17115810453645872 277.0339888176145 767461.4875336842 0.05528597308711696 0.055361175929560295 2.9385234903438064e-07 6.531870833217094 0.2049461195206208 GLAAGSAET(ph)LPANFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GLAAGSAETLPANFR 15 0 A0A2R8Y7R9;Q13136-2;Q13136 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 GLAAGS(0.001)AET(0.999)LPANFR;GLAAGS(0.002)AET(0.998)LPANFR;GLAAGSAET(1)LPANFR 168.93 0.00020394 14056300.0 32915.0 38492.7 31912.2 51611.0 31733.6 40579.0 36000.0 43973.0 45291.0 28005.2 True False 38486.85939911678 42314.000866608105 32673.10787569245 48719.40299511964 25515.62888155367 38450.96580475317 32589.819382570564 42818.75534324473 45953.29519284612 33082.32107095876 1.163366358622956 1.2790517562491512 0.987630456932312 1.4726718506425434 0.7712768649704119 1.1622813805077077 0.9851128435839849 1.294309285355225 1.389058980906455 1.0 15.013772837761461 -10.05563006143037 14.10916847594833 1.000000122131482 1.1607827579718062 0.05922457778081325 0.1984356644542107 0.0 0.0 0.1857187238510492 0.04504340677016434 8.797716004225244e-11 10.05563006143037 0.16078263584032415 GLAAGSAET(ph)LPANFR ddPTM_PC-9_Lapatinib_30min_R1 2 GLAAGSAETLPANFR 15 0 A0A2R8Y7R9;Q13136-2;Q13136 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 GLAAGS(0.001)AET(0.999)LPANFR;GLAAGSAET(1)LPANFR 139.66 4.2063999999999996e-05 9211100.0 50190.0 42928.0 45359.0 28832.0 31241.0 37926.0 27808.9 29464.0 29569.0 28776.0 True False 49474.28139628124 42828.60285348847 41629.75811080339 30952.401460732468 29403.465802169183 36303.993389824114 29248.708772007263 30833.00500362025 26238.62784462611 33749.893258390184 1.4659092702161953 1.2689996535867956 1.2334782155334456 0.917111091989535 0.8712165569548732 1.0756772802769972 0.8666311489662584 0.9135734079975261 0.7774432838570006 1.0 15.042595318873373 -5.499621879089902 1.5024754212956353 0.9093274547634598 1.421243167755588 0.8211929506186866 0.08796034628048634 0.1806237594883855 0.75765721581373 0.02714741474743534 0.09083043857259836 3.165032113746247e-06 5.499621879089902 0.5119157129921281 GLAEVQQDGEAEEGAT(ph)SDGEKKR ddPTM_PC-9_AZD4547_30min_R2 1 GLAEVQQDGEAEEGATSDGEKKR 23 2 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 GLAEVQQDGEAEEGAT(0.5)S(0.5)DGEKKR 60.81399999999999 0.0022702 9396900.0 55574.0 35469.0 47020.0 59850.0 47759.0 53661.0 49131.0 56447.0 39712.0 54708.0 True False 73245.37598899017 46933.66061590121 46396.484077677786 46052.507173282356 41128.487230347724 50305.569187109315 53503.56382064142 47724.41317301941 41811.095246345176 52792.689571819195 1.3874151247654685 0.8890181765043934 0.8788429696229056 0.872327353404348 0.7790564861143608 0.9528889244915927 1.0134653917917016 0.9039966245344463 0.7919864584558691 1.0 15.688050546847686 -4.761005360081479 24.999999833180205 0.8951663719051122 1.387415679398421 0.8016013938866845 0.07303978038755142 4.54157917622345 261306.90571044263 0.018714465743572894 0.10694892617455741 1.733782599201462e-05 4.761005360081479 0.49224930749330875 GLAEVQQDGEAEEGATS(ph)DGEKKR ddPTM_PC-9_Lapatinib_30min_R1 2 GLAEVQQDGEAEEGATSDGEKKR 23 2 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 GLAEVQQDGEAEEGAT(0.261)S(0.739)DGEKKR;GLAEVQQDGEAEEGAT(0.412)S(0.588)DGEKKR 67.312 0.00047544 37742000.0 268887.0 162425.0 167763.0 138983.0 154294.0 144979.0 130901.0 115877.0 143759.0 131811.0 True False 265052.6220721638 162048.91489186246 153970.17372390727 149204.27345369657 145218.73027367535 138778.5861325558 137678.4132764879 121261.06844978628 127567.34757061813 154594.35572288293 1.7145038758548345 1.0482201250758607 0.9959624528589224 0.9651340293506685 0.9393533780365578 0.8976950386294983 0.8905785248931236 0.7843822491627831 0.8251746771356137 1.0 17.238128121518102 -2.295417731830077 1.0699450536245723 0.8906908989425736 199.99995154938463 0.9306695419210865 0.06539731665844438 93.58103192715842 0.5943618263425678 0.021318973821723132 45143.77908049089 0.005065032870818815 2.295417731830077 199.10926065044205 GLAGPPAS(ph)PGK ddPTM_PC-9_AZD4547_30min_R2 4 GLAGPPASPGK 11 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 GLAGPPAS(1)PGK;GLAGPPAS(1)PGK;GLAGPPAS(1)PGK;GLAGPPAS(1)PGK 110.98 0.0018694000000000002 265145000.0 683953.0 857940.0 922431.0 1066328.0 1126650.0 1011517.0 1116270.0 1213946.0 1093962.0 1149000.0 True False 901435.8268938316 1135252.3270688858 910198.9622342916 820502.554203373 970234.0948946014 948266.682086381 1215615.8674984744 1026358.5394039409 1151786.5979523135 1108773.8597283796 0.8130024161235724 1.0238808546108695 0.8209058630379925 0.740008926982076 0.8750513789460036 0.8552390316260534 1.0963605038418458 0.9256698562999778 1.038793066635311 1.0 20.080533719569964 -7.238093389988212 23.77827555008624 1.009011668913144 0.8565505356055241 0.5042222491270867 0.0778692421539747 382.2089742608923 389286.38596864254 0.030449530404523587 0.023565746272092902 5.779717479247662e-08 7.238093389988212 -0.15246113330762 GLAGPPAS(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 GLAGPPASPGK 11 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 GLAGPPAS(1)PGK;GLAGPPAS(1)PGK;GLAGPPAS(1)PGK;GLAGPPAS(1)PGK;GLAGPPAS(1)PGK;GLAGPPAS(1)PGK 110.98 0.0018694000000000002 266469500.0 643723.0 707395.0 800104.0 1003051.0 1174831.0 865723.0 916574.0 932431.0 783776.0 751565.0 True False 752692.5897912083 777620.5005893126 819181.513771318 946853.3044052202 944631.299144899 820322.9618617599 829749.4752988958 907955.6742423099 795237.2412414859 887817.7851147347 0.8478007564287937 0.8758784895132722 0.922691038077654 1.0664950852306436 1.063992313493497 0.9239767164111808 0.934594338174545 1.0226824574425175 0.8957212330891926 1.0 19.759904084023255 -5.4792091769781734 4.056177772885948 0.9868256154588002 0.865585197311925 0.45914536952365437 0.054343860403225676 0.20501144241546246 7.119637711152059 0.015502738084991332 0.03266545289645084 3.3173463981106025e-06 5.4792091769781734 -0.12124041814687525 GLAGPPAS(ph)PGK ddPTM_PC-9_Lapatinib_30min_R1 4 GLAGPPASPGK 11 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 GLAGPPAS(1)PGK;GLAGPPAS(1)PGK;GLAGPPAS(1)PGK;GLAGPPAS(1)PGK 109.16 0.0020956 282286000.0 1133060.0 1305910.0 971150.0 1027290.0 959300.0 852810.0 780390.0 764170.0 958480.0 606930.0 True False 1116902.3566222463 1302886.2456298703 891305.7957474081 1102840.3335389823 902875.8600563644 816337.3042972075 820794.7757224047 799676.1279397378 850525.8891581458 711837.0418166089 1.5690421978770737 1.8303153237219902 1.2521205604484908 1.5492876441559331 1.2683743708422708 1.146803631086567 1.1530655578525888 1.1233977454993962 1.1948322989593276 1.0 19.441187482663373 -5.753559794422946 0.5435617463532696 1.0811170531324688 1.8139088542536517 0.717971173063109 0.12960584877485576 0.8508989250844478 0.39100571948125584 0.08563732232803774 0.35299965755229984 1.7637629097998955e-06 5.753559794422946 0.7327918011211829 GLAS(ph)PTAITPVASPICGK ddPTM_PC-9_AZD4547_30min_R2 2 GLASPTAITPVASPICGK 18 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425;A0A0J9YWY6 O95425-2 SVIL Supervillin 1 GLAS(0.987)PT(0.013)AITPVASPICGK;GLAS(0.914)PT(0.086)AITPVASPICGK 259.29 1.6234999999999997e-65 111786000.0 115752.0 120172.0 163787.0 208719.0 191044.0 179923.0 153354.0 198023.0 154038.0 144863.0 True False 152558.72820883163 159015.24890845752 161615.07736347543 160602.05922640485 164520.83825948092 168672.3863672365 167002.20891393683 167423.0954658502 162180.13420519026 139791.39046286544 1.0913313595615013 1.1375181860766936 1.1561161014877186 1.1488694596615205 1.176902509623328 1.2066006769711837 1.1946530352189304 1.1976638540577713 1.1601582448546588 1.0 17.09291598451344 -4.4435166214943 1.0446235870648553 1.1681147395073344 0.9998166759278058 0.07479698637123267 0.056367562725278306 6.33842482681483 3.5167824206661216 0.016741707858608106 1.4057307357726154 3.6014996632558285e-05 4.4435166214943 -0.1682980635795286 GLAS(ph)PTAITPVASPICGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLASPTAITPVASPICGK 18 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425;A0A0J9YWY6 O95425-2 SVIL Supervillin 1 GLAS(0.999)PT(0.001)AITPVASPICGK;GLAS(0.854)PT(0.146)AITPVASPICGK 239.86 1.0860999999999998e-43 66512000.0 118638.0 116294.0 147083.0 148359.0 191482.0 180590.0 199776.0 186864.0 174100.0 157217.0 True False 138721.07019269076 127838.89975972928 150590.01653538403 140046.92621636784 153962.4766650381 171119.54248947406 180851.77102701162 181959.01799877404 176645.88313515965 185719.19757091277 0.7469398533219658 0.6883451007315322 0.8108478741293536 0.754078889248345 0.8290067945520329 0.9213885517900531 0.9737914733233616 0.9797534147179212 0.9511449836396764 1.0 17.502763427076005 -6.652324726706183 1.220755786596821 0.9811340718863308 0.7384408382099452 0.9262526478530965 0.02918572747362473 0.11000487486731192 0.34584963991697154 0.013798140490653305 0.013791066239425623 2.226769546851638e-07 6.652324726706183 -0.24269323367638562 GLAS(ph)PTAITPVASPICGK ddPTM_PC-9_Lapatinib_30min_R1 2 GLASPTAITPVASPICGK 18 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425;A0A0J9YWY6 O95425-2 SVIL Supervillin 1 GLAS(1)PTAITPVASPICGK;GLAS(0.969)PT(0.031)AITPVASPICGK 265.43 4.195099999999999e-78 86168000.0 116235.0 116344.0 128473.0 100114.0 153506.0 176896.0 188360.0 160758.0 170700.0 154990.0 True False 114577.46758511163 116074.612616154 117910.44586012159 107476.71753051352 144477.0788844079 169330.57044471666 198112.35914744163 168227.40355593248 151473.96844931104 181779.81498880647 0.630309078002786 0.6385451136216723 0.6486443275749962 0.5912467098568214 0.7947916488599377 0.9315147034072161 1.0898479523683138 0.9254460049169458 0.8332826637470085 1.0 17.47183248457229 -6.553442322810773 2.640088458404888 0.9613524716898626 0.6299499366894449 0.8597693010741707 0.06253033611477578 0.10296091306910891 1.4548752257089865 0.02326959051441077 0.02440629555919848 2.796132047814805e-07 6.553442322810773 -0.3314025350004177 GLAT(ph)SLQNDLQEVPK ddPTM_PC-9_AZD4547_30min_R2 2 GLATSLQNDLQEVPK 15 0 Q8N0X7 Q8N0X7 SPG20 Spartin 1 GLAT(0.705)S(0.295)LQNDLQEVPK;GLAT(0.967)S(0.033)LQNDLQEVPK 163.7 0.00030986 3429900.0 13061.2 18170.4 21116.3 31074.0 25713.0 23847.0 22388.6 31571.0 25859.0 25108.0 True False 17214.389910163012 24043.626458461524 20836.284064854684 23910.369388514227 22143.193788687608 22355.843320195247 24381.1420275348 26692.427379407163 27225.853947805175 24228.976562280415 0.7104877032636332 0.9923500646697787 0.8599737595723518 0.9868501596447044 0.9139137070758512 0.9226903688123065 1.0062803092348223 1.1016737463422965 1.123689804966434 1.0 14.564445845844846 -7.412505765700436 2.1991607766826413 1.0847461367634825 0.9023273330640873 0.504568663340675 0.07967118728923052 0.2590835121187208 2.4513104627793374 0.0407611279198343 0.023473722192641742 3.8680691934416266e-08 7.412505765700436 -0.18241880369939523 GLAT(ph)SLQNDLQEVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLATSLQNDLQEVPK 15 0 Q8N0X7 Q8N0X7 SPG20 Spartin 1 GLAT(0.832)S(0.168)LQNDLQEVPK;GLAT(0.735)S(0.265)LQNDLQEVPK 127.18 0.00022998 1967700.0 11754.9 12991.6 14585.300000000001 18300.4 23023.0 16591.0 15051.2 16711.4 15438.5 13028.9 True False 13744.772400142128 14281.320189506736 14933.068867058277 17275.087918697303 18511.80842198837 15720.938753213735 13625.441374748507 16272.743457191926 15664.258855727503 15390.93643328435 0.8930432829556597 0.9279045658730702 0.9702508311816628 1.1224195482568753 1.20277336614521 1.0214413412309158 0.8852899519019652 1.0572939163078203 1.017758660990378 1.0 13.909793392018395 -5.539171876453487 5.633776988988338 1.0457764478897411 0.9184993082278343 0.3247074075307975 0.07790646548596565 0.21075979368346123 21.87441510757495 0.023660144997162725 0.0436569923571706 2.8895360927818763e-06 5.539171876453487 -0.1272771396619068 GLAT(ph)SLQNDLQEVPK ddPTM_PC-9_Lapatinib_30min_R1 1 GLATSLQNDLQEVPK 15 0 Q8N0X7 Q8N0X7 SPG20 Spartin 1 GLAT(0.773)S(0.227)LQNDLQEVPK 91.81200000000001 0.012605 0.0 6749.4 6987.9 7941.9 6445.6 6399.4 6641.4 5113.4 4630.3 7358.8 5590.4 True False 6653.1523183116315 6971.719946885297 7288.94763862055 6919.630925891277 6022.999873704479 6357.362803859561 5378.146831941646 4845.4406417412 6529.974452400647 6556.693191260233 1.0147115511184774 1.0632981814946405 1.1116804501904065 1.0553537772843822 0.9186032803445581 0.9695989454461023 0.8202529346821452 0.7390067676492698 0.9959249673455515 1.0 12.67875267276739 -6.447922315402905 1.7022227206034635 0.8778341648069635 1.0683561954664782 0.4562403580008212 0.08011742990261606 0.2993752427865418 1.739842191583111 0.03046894022633824 0.035273006384710606 3.565148994665326e-07 6.447922315402905 0.19052203065951467 GLCAIAQAESLR ddPTM_PC-9_Lapatinib_30min_R1 2 GLCAIAQAESLR 12 0 P23396;P23396-2;F2Z2S8;H0YCJ7;H0YF32 P23396 RPS3 40S ribosomal protein S3 0 ; 157.38 0.0019309000000000002 13322300.0 32812.0 30215.0 33538.0 34890.0 28328.0 33355.0 35276.0 31580.0 24436.7 29170.0 False True 32344.094863016166 30145.03902390405 30780.635100423846 37455.92698962808 26661.802734990848 31928.48440430266 37102.41867320638 33047.32208845802 21684.381516141068 34211.99563341821 0.9454021685721985 0.8811248354790047 0.8997029997968718 1.0948185364855245 0.7793115321500758 0.933254076915495 1.0844856602566852 0.9659571584937728 0.6338239297259761 1.0 15.062214640523534 GLDDDRGPR ddPTM_PC-9_AZD4547_30min_R2 1 GLDDDRGPR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 93.14299999999999 0.008404700000000001 5846000.0 19893.0 16126.0 25603.0 35491.0 29764.0 25736.0 22686.0 34002.0 27026.0 22881.0 False True 26218.560199895343 21338.414138882494 25263.487491296994 27309.098280483966 25631.78236403756 24126.723851576502 24705.01005139468 28747.772188229777 28454.539185327474 22079.943154434375 1.1874378487532382 0.9664161718911419 1.1441826328354137 1.2368282875311392 1.1608626971890488 1.092698639793874 1.1188892054023747 1.3019857880592542 1.288705273664297 1.0 14.430448837402796 -5.509793711810788 24.367324019269304 1.1790521951536332 1.0715200934039697 0.12030167550765214 0.09920956171157481 772.3631179809523 1438313.2344713865 0.0263179625808784 0.050994199933997106 3.091763659494191e-06 5.509793711810788 -0.10753210174966354 GLDDDRGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLDDDRGPR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 77.318 0.030117 4612800.0 35042.0 41269.0 43986.0 35734.0 47561.0 41885.0 36441.0 37133.0 34903.0 33090.0 False True 40973.918488951866 45365.91358268057 45034.79305783392 33731.93983119112 38241.76346949523 39688.476865671575 32989.04467000704 36158.298095665676 35413.390345011314 39088.95505970415 1.0482224051875686 1.1605813845212554 1.1521104360310515 0.8629532250137981 0.9783265736084547 1.0153373710054852 0.8439479801805866 0.9250259578553017 0.9059692256014823 1.0 15.2544733980387 -5.753968607321073 24.999269228615937 0.9315549505109709 1.1243324522049345 0.6785038042511287 0.05903271626490169 95.3554937962742 319082.16400518257 0.016145404905749793 0.02727634571706822 1.762103414245649e-06 5.753968607321073 0.19277750169396357 GLDDDRGPR ddPTM_PC-9_Lapatinib_30min_R1 2 GLDDDRGPR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 ; 82.75 0.019858 9785700.0 65617.0 73874.0 71591.0 69061.0 79453.0 80146.0 73505.0 71184.0 78705.0 64615.0 False True 64681.28954731586 73702.94929180517 65705.06432925165 74139.97632074244 74779.73075060816 76718.34240945106 77310.72923727274 74491.4685099683 69840.4140996077 75783.61665592443 0.8534996401792783 0.9725446282992011 0.867008823656018 0.9783114028109201 0.9867532594825323 1.0123341402109443 1.0201509593858757 0.9829495054079724 0.9215766834763208 1.0 16.20959837142907 -5.860566411505695 6.791667828326053 0.9886051795010109 0.9055131144886099 0.5206830798412507 0.038643862431056206 0.17753501984649916 10.452006764981077 0.010730445722119196 0.016055197106297176 1.3785851261721633e-06 5.860566411505695 -0.08309206501240096 GLDDDRGPWR ddPTM_PC-9_AZD4547_30min_R2 1 GLDDDRGPWR 10 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 108.57 0.002604 9117500.0 34229.0 32590.0 40150.0 51171.0 40113.0 46962.0 38945.0 57740.0 31071.0 36085.0 False True 45113.109992571124 43124.080167814725 39617.584766456035 39374.31653406904 34544.00235078075 44025.45871610719 42411.02955353809 48817.60973320358 32713.34962729631 34821.67513341918 1.2955468058248298 1.2384263537749087 1.1377277116813405 1.1307415965259116 0.9920258637307215 1.2643119134109353 1.217949147794881 1.4019316861167364 0.9394536449483023 1.0 15.08769798657484 -8.294687512527128 24.895806522953727 0.9697266499713896 1.2005722181098746 0.45534234002479446 0.1046488142761882 689.3801144430628 516193.3629053696 0.10577362960300477 0.02731767029220067 5.073556340620059e-09 8.294687512527128 0.230845568138485 GLDDDRGPWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLDDDRGPWR 10 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 87.806 0.01347 5305700.0 23516.0 34942.0 29793.0 34562.0 41729.0 33857.0 39140.0 38459.0 30799.0 28072.0 False True 27496.794337828665 38410.810836366916 30503.378110581685 32625.603191515846 33552.502004132926 32081.47931815787 35432.37585093921 37449.492000678794 31249.377109016525 33161.231382170285 0.8291849606228072 1.1583047201624472 0.9198505857349544 0.9838477593162469 1.011799037781601 0.9674393254107879 1.0684879413130008 1.1293154819580724 0.9423467044658148 1.0 15.017209959240965 -7.258861317286059 24.84680221765886 1.045813822063346 0.9856855120557199 0.07962104830501726 0.08940540430285042 531.9796559531114 5127132.621387077 0.03320337994160096 0.0245763977770106 5.5098361322461764e-08 7.258861317286059 -0.060128310007626085 GLDDDRGPWR ddPTM_PC-9_Lapatinib_30min_R1 3 GLDDDRGPWR 10 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 ;; 101.46 0.0046581 20527800.0 97316.0 130316.0 127964.0 96747.0 117935.0 115221.0 105714.0 105699.0 120095.0 91683.0 False True 95928.2559944311 130014.2613085909 117443.29387532438 103862.09711853087 110998.29516913102 110293.26642326945 111187.35365742526 110610.1614131707 106568.63644358519 107530.28439008172 0.8921045502533725 1.2090943685868558 1.0921880709371303 0.9658869378765523 1.0322514796526399 1.0256949197973346 1.0340096679562103 1.0286419499451547 0.9910569570986345 1.0 16.714383506217246 -5.739739328469125 24.97902913471176 1.0147176467919519 1.0789255598603624 0.08568446950490582 0.07495117791461141 480.40443348490163 552991.2661695586 0.019387393028957246 0.033539653725723824 1.820793404363757e-06 5.739739328469125 0.06420791306841056 GLDDSTGGTPLT(ph)PAAR ddPTM_PC-9_AZD4547_30min_R2 1 GLDDSTGGTPLTPAAR 16 0 Q9NXR1;Q9NXR1-1;I3L533;I3L2R9;I3L2T8;I3L2R3;I3L522 Q9NXR1 NDE1 Nuclear distribution protein nudE homolog 1 1 GLDDSTGGTPLT(1)PAAR 115.83 0.0012235 0.0 7862.2 5365.6 11082.0 11206.0 10255.0 9381.2 8733.7 10207.0 8780.7 11365.0 True False 10362.216056080884 7099.925269973209 10935.045439149837 8622.629830974136 8831.270264185092 8794.592080991975 9510.98238058123 8629.742683526309 9244.829875845671 10967.114809236775 0.9448443128682824 0.6473831443793655 0.9970758608216695 0.7862259109124985 0.805250097021614 0.8019057185017296 0.8672273926202401 0.786874472788242 0.8429591589630708 1.0 13.420896415966975 -8.572969180030547 19.508349076670697 1.0000000013876105 0.8264144519136305 0.2410527070726728 0.0900533122136172 2401.781236343537 935404.406794842 0.07925953905520375 0.020464725001994682 2.673196106903807e-09 8.572969180030547 -0.17358554947397997 GLDDSTGGTPLT(ph)PAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLDDSTGGTPLTPAAR 16 0 Q9NXR1;Q9NXR1-1;I3L533;I3L2R9;I3L2T8;I3L2R3;I3L522 Q9NXR1 NDE1 Nuclear distribution protein nudE homolog 1 1 GLDDSTGGTPLT(1)PAAR 106.6 0.0024471 1553800.0 7158.6 6839.0 6477.8 7922.0 10377.0 8858.2 9015.4 7373.1 9281.8 7573.3 True False 8370.409591205149 7517.930722623585 6632.2553191933075 7478.156023470527 8343.701341917786 8393.660398030124 8161.3960461562965 7179.563937445201 9417.528765559577 8946.27933979019 0.9356302517825755 0.840341603149617 0.7413423018991993 0.8358956544325729 0.9326448487705576 0.9382291877135791 0.912267070608562 0.802519535189651 1.0526754651705788 1.0 13.127072090605568 -6.252344262784332 8.880850556584534 0.9284312672562457 0.8314321125901895 0.2981924334652404 0.07473885888679542 0.24072906129782912 184.9549782037364 0.022424357103646982 0.027764885283715426 5.593140606234806e-07 6.252344262784332 -0.09699915466605624 GLDDTEEPS(ph)PPEDK ddPTM_PC-9_AZD4547_30min_R2 2 GLDDTEEPSPPEDK 14 0 O94806;O94806-2 O94806 PRKD3 Serine/threonine-protein kinase D3 1 GLDDTEEPS(1)PPEDK;GLDDTEEPS(1)PPEDK 218.16 1.4837e-15 6541500.0 35137.0 32005.0 33077.0 42430.0 36808.0 34887.0 33820.0 39168.0 33163.0 36135.0 True False 46309.835104997874 42349.99035811323 32638.377367872134 32648.41903696527 31697.844552328115 32705.51037495916 36829.91448197865 33115.485591100056 34915.928476393645 34869.92464863801 1.3280738507935577 1.2145133889690636 0.936003667824013 0.9362916428969253 0.9090310596230728 0.9379289087806105 1.056208605355194 0.9496861815671724 1.0013192981693877 1.0 15.089695626108755 -5.131525034262714 3.3796165962192473 0.9628495521569824 1.3108364547018054 0.8941740344193372 0.042711524889318425 0.07346739545319823 1.5103732534827519 0.01191114115530453 0.04059020345748335 7.387116798247326e-06 5.131525034262714 0.347986902544823 GLDDTEEPS(ph)PPEDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLDDTEEPSPPEDK 14 0 O94806;O94806-2 O94806 PRKD3 Serine/threonine-protein kinase D3 1 GLDDT(0.002)EEPS(0.998)PPEDK;GLDDT(0.002)EEPS(0.998)PPEDK 145.81 0.00018893 2414100.0 31494.0 26894.0 28316.0 35112.0 31547.0 29426.0 33040.0 33290.0 24126.0 25205.0 True False 36825.31216514614 29563.858583745943 28991.160829027987 33144.78847463991 25365.59181203434 27882.848758487555 29910.21201111477 32416.172773670583 24478.797108092218 29774.466977329776 1.236808443730827 0.9929265436138894 0.9736920177648118 1.113195023772425 0.8519242957849642 0.9364684439092563 1.0045591087789532 1.088723865261877 0.8221405651604218 1.0 14.861788060735524 -4.760860873494492 5.081967158139182 0.9776975003539701 1.2528255808358186 0.4548555790319846 0.08581299418609332 0.1569590734520285 10.985945934888688 0.02089058304800574 0.15435616747880546 1.734359511910557e-05 4.760860873494492 0.27512808048184856 GLDDTEEPS(ph)PPEDK ddPTM_PC-9_Lapatinib_30min_R1 1 GLDDTEEPSPPEDK 14 0 O94806;O94806-2 O94806 PRKD3 Serine/threonine-protein kinase D3 1 GLDDTEEPS(1)PPEDK 184.0 6.9008e-06 2693600.0 22584.0 22284.0 20165.0 18446.0 20814.0 16376.0 21141.0 21901.0 22355.0 19244.0 True False 22261.94801860162 22232.40276712489 18507.111539151003 19802.580374052148 19589.76144189845 15675.636654320504 22235.57753629255 22918.60041353133 19837.14449141388 22570.29975898182 0.9863381637074851 0.9850291314043155 0.8199763289269618 0.8773733882808419 0.8679442298546669 0.6945249651849399 0.9851697927690983 1.0154318134127087 0.8789047865223729 1.0 14.462137958820215 -10.153294816330625 6.906060384838465 0.9999995427657664 0.8993392082150384 0.09252038953876363 0.09267632474267411 6.978133772511434e-11 0.0 0.09509466871258906 0.02306384491383081 7.025952084489247e-11 10.153294816330625 -0.10066033455072798 GLDHDFGPSR ddPTM_PC-9_AZD4547_30min_R2 2 GLDHDFGPSR 10 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6 Q9UDY2-7 TJP2 Tight junction protein ZO-2 0 ; 99.788 0.0035573999999999996 2916600.0 38472.0 36200.0 68509.0 106497.0 86620.0 74543.0 48736.0 77290.0 56679.0 61590.0 False True 50705.29573268852 47900.942070417135 67600.52589701462 81945.76201224807 74594.30817003551 69881.81442602069 53073.40958585784 65346.60644751137 59674.936227528124 59433.752846536976 0.8531397279188129 0.8059551984560265 1.1374096815249906 1.3787748221761973 1.2550832582058948 1.1757934015451035 0.892984323619912 1.0994864587508362 1.0040580203914415 1.0 15.858994859978885 -5.263314817691771 24.59357987894928 1.129746157186919 0.8295474390173179 0.43612871816337306 0.13062171640417242 119.23147046874065 1563576.140311586 0.03754221889511528 0.0851014921414304 5.453623875619068e-06 5.263314817691771 -0.3001987181696011 GLDHDFGPSR ddPTM_PC-9_Lapatinib_30min_R1 2 GLDHDFGPSR 10 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6 Q9UDY2-7 TJP2 Tight junction protein ZO-2 0 ; 84.81700000000001 0.011973000000000001 2661400.0 44019.0 36335.0 51827.0 36879.0 47480.0 47236.0 33324.0 37999.0 49841.0 31214.0 False True 43391.28098790404 36250.868539915755 47565.98411800546 39591.20468473755 44687.31974927159 45215.826392494106 35049.353664415736 39764.5722621696 44227.381731002395 36609.298309959406 1.1852530092361706 0.990209324226623 1.2992869657123511 1.0814521586710373 1.2206549104251636 1.2350913150442255 0.957389386916512 1.0861877746329767 1.2080914896686377 1.0 15.15992250133604 -10.457196479527637 4.853293891127808 0.9999990801766993 1.1370917893925934 0.1384273841697511 0.10478971192082542 1.0258280218893032e-06 2.251864312284207e-07 0.09951493959984775 0.024135755515709047 3.489823963430371e-11 10.457196479527637 0.13709270921589412 GLDQDHAR ddPTM_PC-9_AZD4547_30min_R2 2 GLDQDHAR 8 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6 Q9UDY2-7 TJP2 Tight junction protein ZO-2 0 ; 123.72 0.0027578000000000004 3248600.0 22980.4 19111.0 23217.0 31761.0 25102.0 28075.0 24840.0 20447.3 29305.0 36180.0 False True 30287.689177985958 25288.257014026007 22909.127410281682 24438.99215255843 21617.020592059896 26319.46581182042 27050.71187854376 17287.63961721049 30854.00247265676 34913.34921233494 0.8675102750464647 0.7243148418740538 0.6561710041323635 0.6999899094161981 0.6191620420198062 0.7538510743197823 0.7747956723953227 0.4951584424648306 0.8837308126759719 1.0 15.091491139770369 -8.51456866954674 24.089889672294397 1.0000000129061049 0.6993760358640086 0.5362310789273816 0.09356969578334391 216.3434942100525 627152.0629911774 0.08767748785669956 0.02263823003704554 3.0579566918925772e-09 8.51456866954674 -0.3006239770420962 GLDQDHAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLDQDHAR 8 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6 Q9UDY2-7 TJP2 Tight junction protein ZO-2 0 ; 113.66 0.0031141 2694300.0 13921.7 20987.6 22272.3 18906.3 28925.4 25993.0 16884.5 25033.6 26612.3 21228.6 False True 16278.368843891374 23071.110225783686 22803.35610016813 17847.04130605162 23257.675512721296 24629.88132193867 15285.077926805914 24376.49452529168 27001.454541974737 25077.177134494857 0.6491308314562926 0.9200042772776155 0.9093270736920792 0.7116846210533864 0.9274439219368615 0.9821632311261657 0.6095214722465934 0.9720589520325493 1.0767342112375538 1.0 14.614087336809279 -7.9851531077074895 24.99957999732849 1.0337103473746885 0.8271439011547003 0.37393514539119854 0.12034727683948414 236.36252356369823 397993.1797065191 0.06427215124600656 0.03085792077190794 1.0347772983309085e-08 7.9851531077074895 -0.2065664462199882 GLDQDHAR ddPTM_PC-9_Lapatinib_30min_R1 2 GLDQDHAR 8 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6 Q9UDY2-7 TJP2 Tight junction protein ZO-2 0 ; 119.21 0.0029118000000000004 3318400.0 20129.2 21599.7 25165.0 18377.9 24757.0 19405.7 22578.0 24228.9 27039.0 21114.3 False True 19842.153916756808 21549.68722173162 23096.03083970916 19729.472072877194 23300.841934134714 18575.763447896163 23746.978364997558 25354.663145948085 23993.583086707215 24763.87862196373 0.8012538835155768 0.8702064628365057 0.9326499775049248 0.7967036333064001 0.940920535504022 0.7501152679459846 0.9589361475845607 1.0238567040730193 0.9688943906156396 1.0 14.595949672713953 -7.486613626399571 12.279706938495412 0.9961192639423289 0.8551919534472997 0.5935234203074017 0.05698379994767532 1.046014330074901 353.8670740513967 0.022613913206624134 0.015132339228871073 3.261267132466875e-08 7.486613626399571 -0.14092731049502916 GLDSSSTAPS(ph)ALGER ddPTM_PC-9_AZD4547_30min_R2 2 GLDSSSTAPSALGER 15 0 J3KTM2;O15534-4;O15534;J3QL46 J3KTM2 PER1 Period circadian protein homolog 1 1 GLDSS(0.004)S(0.088)T(0.088)APS(0.82)ALGER;GLDSSSTAPS(1)ALGER 159.41 0.00011382 22868000.0 50307.0 45285.0 84174.0 124896.0 97398.0 73235.0 73211.0 74449.0 60832.0 77709.0 True False 66303.5795493961 59922.49065355905 83057.79776168548 96103.1568239644 83875.96891185752 68655.60387279323 79726.63717150012 62944.61771782601 64047.45532901062 74988.43156277869 0.8841841090367144 0.7990897983163342 1.1076081474267307 1.281573101625801 1.1185187790151123 0.9155492712941495 1.0631858209323222 0.8393910421386817 0.8540978120790735 1.0 16.194380428300597 -7.758856969288068 24.999706087661266 0.8850583079615303 1.0281333215588724 0.15330471309275673 0.13492936200938002 128.31359781350798 1242214.6221826083 0.07465789727491752 0.040533443068572254 1.7423806152111168e-08 7.758856969288068 0.1430750135973421 GLDSSSTAPS(ph)ALGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GLDSSSTAPSALGER 15 0 J3KTM2;O15534-4;O15534;J3QL46 J3KTM2 PER1 Period circadian protein homolog 1 1 GLDS(0.01)S(0.109)S(0.109)T(0.109)APS(0.664)ALGER;GLDSSS(0.001)T(0.001)APS(0.998)ALGER;GLDSSS(0.007)T(0.007)APS(0.985)ALGER 144.88 9.18e-05 19718800.0 88231.0 60201.5 71650.8 121552.0 110769.0 147900.0 116817.0 181635.0 148234.6 118163.3 True False 103166.76565831593 66177.907062147 73359.22680917234 114741.83551690108 89064.60961191983 140143.86363693036 105751.24807815943 176867.27370819045 150402.25059268836 139585.3709098321 0.7390943978288278 0.47410345819760663 0.5255509680635527 0.82201906094458 0.6380655009288392 1.0040010835194113 0.7576098224968827 1.2670903301352499 1.0774929321916094 1.0 17.090788223851433 -6.906720913503817 0.8533779497414555 1.1092188976979365 0.5843168233493385 0.632643667467756 0.1461230856936899 0.3634599230878573 0.5623046408992741 0.0972540669068091 0.07878480658453554 1.2395929183375992e-07 6.906720913503817 -0.5249020743485979 GLDSSSTAPS(ph)ALGER ddPTM_PC-9_Lapatinib_30min_R1 2 GLDSSSTAPSALGER 15 0 J3KTM2;O15534-4;O15534;J3QL46 J3KTM2 PER1 Period circadian protein homolog 1 1 GLDSS(0.004)S(0.001)T(0.002)APS(0.992)ALGER;GLDSS(0.001)S(0.025)T(0.142)APS(0.832)ALGER 158.89 5.8181000000000004e-05 22830000.0 57348.0 53235.0 59161.0 49224.0 48388.0 61900.0 49206.0 47932.0 50675.0 30316.0 True False 56530.20700366484 53111.737628248644 54297.01094806409 52844.09716645033 45541.91297446827 59252.68129594766 51753.645913192915 50159.09570436892 44967.44786859306 35556.08020646916 1.5898886118886522 1.4937455793730987 1.5270808996033585 1.4862183024560662 1.2808474024699232 1.666457071529698 1.4555498134965037 1.410703750613175 1.2646908097707454 1.0 15.117808666079581 -8.533297219121302 1.2924344620909738 1.0013272731164842 1.499724344840614 0.7393574945439212 0.09303250484540841 0.24401406962990993 0.8944417905441903 0.08790121428243572 0.026893863949301686 2.928888109254123e-09 8.533297219121302 0.4983970717241297 GLEERLS(ph)PPLPHEER ddPTM_PC-9_Lapatinib_30min_R1 1 GLEERLSPPLPHEER 15 1 Q9UPV0 Q9UPV0 CEP164 Centrosomal protein of 164 kDa 1 GLEERLS(1)PPLPHEER 60.528 0.021302 1262300.0 6359.3 3181.5 5556.0 4735.0 4659.9 4442.1 5566.5 4048.7 4452.6 4573.0 True False 6268.615215847205 3174.1334322207776 5099.207126780212 5083.227695496956 4385.813843715894 4252.12173804086 5854.70613290632 4236.817382506018 3951.101300043367 5363.436956860523 1.1687683226757877 0.5918095910795883 0.9507349797889714 0.9477556530229848 0.817724507436575 0.7927979339072591 1.0915959635579198 0.7899444734008825 0.7366733927932912 1.0 12.388942078544957 -4.712774566723509 24.078536881711603 0.8608645026578341 1.1687765567779222 0.31689952767980334 0.13695263165788676 12800.245152117546 6332476.484721136 0.03305733943664783 28.669400581229812 1.937427381430991e-05 4.712774566723509 0.30791205412008815 GLEFPMTDLDMLS(ph)PIHTPQR ddPTM_PC-9_AZD4547_30min_R2 3 GLEFPMTDLDMLSPIHTPQR 20 0 O60784-4;O60784;O60784-2;V9GYF4;B0QY02;B0QY01 O60784-4 TOM1 Target of Myb protein 1 1 GLEFPMTDLDMLS(1)PIHTPQR;GLEFPMT(0.002)DLDMLS(0.997)PIHT(0.001)PQR;GLEFPMTDLDMLS(0.995)PIHT(0.005)PQR 91.565 0.00045075 30616100.0 65580.9 64230.5 80498.0 116208.0 85257.0 89619.0 77645.0 102544.0 69180.0 71319.0 True False 86434.26203253982 84991.75302911404 79430.54392354113 89418.04099570258 73420.53719294281 84015.10976276161 84555.25458170428 86698.18102669953 72836.71356623087 68822.14351781413 1.25590772990334 1.234947775305989 1.1541422551446847 1.2992626562489638 1.066815612535207 1.2207569463600751 1.2286053624560205 1.2597425275523177 1.058332534315465 1.0 16.070585206154448 -8.40633174291571 4.303572880240784 1.0027358405990754 1.2117860028458507 0.6007216700753326 0.06127113569135982 0.1421690679122658 4.034483144265126 0.05728863013903494 0.015020902128762243 3.9234512169193025e-09 8.40633174291571 0.2090501622467753 GLEFPMTDLDMLS(ph)PIHTPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLEFPMTDLDMLSPIHTPQR 20 0 O60784-4;O60784;O60784-2;V9GYF4;B0QY02;B0QY01 O60784-4 TOM1 Target of Myb protein 1 1 GLEFPMTDLDMLS(0.997)PIHT(0.003)PQR;GLEFPMT(0.001)DLDMLS(0.995)PIHT(0.004)PQR 85.387 0.00039368 20792100.0 39647.0 40355.0 50673.0 45549.0 76298.0 82285.0 95604.0 83207.0 81744.0 62072.0 True False 46358.45403605603 44361.17770309616 51881.23649842268 42997.03720185046 61347.95460977585 77969.82974553632 86547.69700697983 81022.90441510412 82939.3513555454 73325.16223831823 0.6322311825970983 0.6049925612017797 0.7075502448913862 0.5863885723444208 0.83665624101022 1.0633434330785685 1.1803273851026241 1.1049809088968263 1.1311171884758953 1.0 16.16202073762385 -6.608103249308004 2.425416845332724 1.1146489977860226 0.6359643742344481 0.9433513604482352 0.05356567282344206 0.05817488557934109 0.6955950722943032 0.01863562985778641 0.01893616841696559 2.46545312994472e-07 6.608103249308004 -0.4786846235515745 GLEFPMTDLDMLS(ph)PIHTPQR ddPTM_PC-9_Lapatinib_30min_R1 2 GLEFPMTDLDMLSPIHTPQR 20 0 O60784-4;O60784;O60784-2;V9GYF4;B0QY02;B0QY01 O60784-4 TOM1 Target of Myb protein 1 1 GLEFPMT(0.015)DLDMLS(0.984)PIHT(0.001)PQR;GLEFPMTDLDMLS(0.995)PIHT(0.004)PQR 72.676 0.0016202999999999999 11009900.0 18436.6 14211.099999999999 23231.0 16142.8 30310.0 37487.0 46133.0 42532.0 41363.0 33051.0 True False 18173.690703141638 14178.195071077376 21321.036854253278 17329.995362802176 28527.225391752778 35883.7683964651 48521.5410094974 44508.19199069972 36704.26336830025 38763.82131231078 0.4688312474851379 0.3657584466930407 0.5500241238466872 0.4470662276347467 0.7359239730757138 0.9257025541253587 1.2517223371393398 1.1481889680614286 0.9468690682629773 1.0 15.242423177252343 -6.62645447140597 1.8100806092697257 1.098109885155723 0.45128541667576183 0.90253871830247 0.09310830367805295 0.09695206339997564 0.6513016187653771 0.037106641675521385 0.03746524305839992 2.3634451543048541e-07 6.62645447140597 -0.6468244684799611 down GLEGERPAR ddPTM_PC-9_AZD4547_30min_R2 3 GLEGERPAR 9 1 P46783;F6U211;A0A2R8Y7H1;S4R435;A0A2R8YFH6;A0A1W2PQS6;A0A2R8Y6L3 P46783 RPS10;RPS10-NUDT3 40S ribosomal protein S10 0 ;; 88.819 0.012734 42346700.0 16590.1 20351.199999999997 29032.699999999997 40323.0 36902.0 29493.8 19942.2 31204.7 21174.9 26112.6 False True 21865.406704483165 26929.327410593156 28647.707428370795 31027.155334139774 31778.79427488625 27649.548023532294 21717.017166839592 26382.73062767056 22294.16198458488 25198.40582205687 0.8677297627036296 1.0686917101327562 1.1368857074003726 1.2313142169883158 1.261143046083867 1.0972737013120835 0.8618409164531384 1.0469999893634945 0.88474493751784 1.0 14.621044844014191 -7.129293322649725 6.62985909245404 0.9531255282318872 1.1241930182842437 0.336109279600332 0.11107716860973883 0.3025857792977852 14.9947145276115 0.04530748067131626 0.03505109202143826 7.425174719347188e-08 7.129293322649725 0.17106749005235644 GLEGERPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLEGERPAR 9 1 P46783;F6U211;A0A2R8Y7H1;S4R435;A0A2R8YFH6;A0A1W2PQS6;A0A2R8Y6L3 P46783 RPS10;RPS10-NUDT3 40S ribosomal protein S10 0 ; 100.02 0.0051265 6861200.0 18266.1 16394.1 16634.8 17811.5 25510.0 22132.5 19795.2 16143.2 21434.9 19919.6 False True 21358.189958080133 18021.597903167596 17031.436719830304 16813.579400662136 20511.49862506725 20971.83273796052 17920.0553511628 15719.458105134247 21748.344861653233 23530.86579653316 0.907666982709445 0.7658705828759921 0.7237913329283266 0.714532968996802 0.8716848246225279 0.8912478154990088 0.7615552910850816 0.6680356872992842 0.9242475414932438 1.0 14.522266783723438 -8.487729025391696 7.277318478995505 0.9999386930247187 0.788265063646791 0.4734376333704621 0.07556376592352489 0.171583805638405 28.783261540602346 0.07638516673935433 0.01975701967305054 3.2529019632640033e-09 8.487729025391696 -0.21167362937792766 GLEGERPAR ddPTM_PC-9_Lapatinib_30min_R1 3 GLEGERPAR 9 1 P46783;F6U211;A0A2R8Y7H1;S4R435;A0A2R8YFH6;A0A1W2PQS6;A0A2R8Y6L3 P46783 RPS10;RPS10-NUDT3 40S ribosomal protein S10 0 ;; 78.149 0.028547000000000003 30910800.0 42412.4 40121.0 38128.4 34181.0 38826.6 35681.8 35940.7 29232.6 39445.0 30040.2 False True 41807.591398518416 40028.102289526905 34993.63013188024 36694.7847644734 36542.89572403259 34155.77259233839 37801.533586804275 30590.853314852997 35002.28872573562 35232.60854394958 1.1866164081029402 1.1361095287507699 0.9932171240806302 1.0415006518379097 1.0371896159334482 0.9694363830521396 1.0729132797433998 0.868254000457945 0.9934628791982104 1.0 15.104623672267712 -1.5228787475495513 0.44810035171671353 0.9735187464556677 6.0559846137612645 0.6099636885438003 0.05270924836993702 56.274433217408045 0.6807671054138152 0.03256183091882685 261.36676686261376 0.029999999843248266 1.5228787475495513 5.082465867305597 GLEGNANS(ph)PAHLR ddPTM_PC-9_AZD4547_30min_R2 1 GLEGNANSPAHLR 13 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 GLEGNANS(1)PAHLR 70.783 0.015534000000000001 9976600.0 23548.0 34475.0 35973.0 40235.0 32349.0 38866.0 29487.0 42780.0 32779.0 30201.0 True False 31035.774171172525 45618.36955463064 35495.974515659356 30959.442374553335 27857.899734385523 36435.70287594698 32111.285876111895 36169.33398660286 34511.631020345216 29143.67218246896 1.0649232525282706 1.5652924336031973 1.2179650626530019 1.062304097462935 0.9558815910351586 1.2502097418548532 1.1018270338433216 1.2410698885214646 1.184189514769017 1.0 14.83089505192964 -5.51912200875022 24.222621289912215 1.1236808529210895 1.3342380605346222 0.2386136814954618 0.14389783664501565 124.00003527721249 799523.1520446714 0.03737936991718594 0.06673704321685404 3.0260631800127554e-06 5.51912200875022 0.2105572076135327 GLEGNANS(ph)PAHLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLEGNANSPAHLR 13 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 GLEGNANS(1)PAHLR;GLEGNANS(1)PAHLR 91.616 0.0028482 14944200.0 60800.0 79205.0 85682.0 70243.0 83110.0 74828.0 68374.0 65690.0 49183.0 50615.0 True False 71092.2391452621 87067.94895239097 87724.98383079446 66307.51244087849 66825.19211012687 70903.88795283451 61897.119735107764 63965.707104308225 49902.2083299055 59791.09883188045 1.1890104134924495 1.4562025226732676 1.4671913636753526 1.1089863497461516 1.117644489157571 1.1858602591031284 1.0352229837613285 1.0698198955026041 0.8346093198624706 1.0 15.867643104325108 -6.553057670971267 0.6465089695126952 0.9548487478505542 1.38590864055786 0.6284188509881652 0.11262379969621429 0.5375148778350685 0.49737283777698776 0.08510947483277347 0.11414627037380194 2.798609661092071e-07 6.553057670971267 0.4310598927073058 GLEGNANS(ph)PAHLR ddPTM_PC-9_Lapatinib_30min_R1 1 GLEGNANSPAHLR 13 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 GLEGNANS(1)PAHLR 114.54 0.00017183 10657000.0 36390.0 57813.0 60040.0 39368.0 53385.0 54809.0 57144.0 50936.0 50218.0 45446.0 True False 35871.071926891316 57679.13755052016 55103.74296110225 42263.254047798175 50244.99925894823 52464.94683601934 60102.6367122606 53302.67251101009 44561.9200210164 53301.280547011454 0.6729870569479699 1.0821341806159321 1.0338164936300365 0.7929125457037041 0.9426602652563365 0.984309312976928 1.1276021156611873 1.0000261150198335 0.8360384509282665 1.0 15.70188257325868 -6.70141392397797 4.1717732807882255 0.9987035335780334 0.9137107837252824 0.10074701637183126 0.12601370511690915 0.5862289438512456 20.511493162877365 0.044098219787087764 0.042932059077588444 1.9887769416873615e-07 6.70141392397797 -0.08499274985275107 GLEPADLAGS(ph)APAEEEGRGSPASGSPDVEGAR ddPTM_PC-9_AZD4547_30min_R2 1 GLEPADLAGSAPAEEEGRGSPASGSPDVEGAR 32 1 E7EUN2 E7EUN2 AGAP1 1 GLEPADLAGS(0.47)APAEEEGRGS(0.424)PAS(0.092)GS(0.014)PDVEGAR 50.413000000000004 0.0038616999999999996 3494600.0 5066.0 4045.0 5882.2 9010.2 7154.4 8200.8 5684.1 5957.0 5181.7 5116.3 True False 6676.882620653989 5352.467145713731 5804.198184638795 6933.037596202322 6161.135053933288 7688.002679593117 6189.973888439234 5036.482528242012 5455.594083349788 4937.179894280523 1.3523677005143817 1.0841142636739443 1.1756100261533249 1.4042505528781524 1.2479057246973433 1.5571647872299095 1.253746879997225 1.020113229837245 1.1050020862455958 1.0 12.2694714976686 -7.70184651055521 5.4270053767056545 1.0467629639658724 1.2981750369181058 0.47523366270800216 0.12316671223184264 0.1869440057175702 10.954966304207572 0.06431183009313968 0.03559453509309769 1.9867969720568648e-08 7.70184651055521 0.25141207295223333 GLEPADLAGSAPAEEEGRGS(ph)PASGSPDVEGAR ddPTM_PC-9_AZD4547_30min_R2 1 GLEPADLAGSAPAEEEGRGSPASGSPDVEGAR 32 1 E7EUN2 E7EUN2 AGAP1 1 GLEPADLAGS(0.012)APAEEEGRGS(0.66)PAS(0.277)GS(0.051)PDVEGAR 67.47 2.6364e-05 4798600.0 4222.8 4175.1 6105.7 9963.9 7885.0 7107.4 4192.9 7136.5 4377.7 5930.9 True False 5565.562560303522 5524.619426469573 6024.734428606488 7666.876795720435 6790.30385500726 6662.973154441046 4566.059977276413 6033.7179054556145 4609.096284748317 5723.260996225461 0.9724460519927465 0.9652922398809186 1.0526751152148839 1.3395993649034712 1.1864396642902573 1.1641917359413336 0.7978074004117177 1.0542447582654193 0.8053269434659812 1.0 12.48262168385623 -7.247709812491779 24.905068582283437 0.9188651678370265 1.1175426829948267 0.37667009648828365 0.12535132807496957 883.1380937693375 1601991.0017511302 0.05158802980870209 0.03974039814597434 5.653145813491218e-08 7.247709812491779 0.1986775151578002 GLEPADLAGSAPAEEEGRGS(ph)PASGSPDVEGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLEPADLAGSAPAEEEGRGSPASGSPDVEGAR 32 1 E7EUN2 E7EUN2 AGAP1 1 GLEPADLAGS(0.001)APAEEEGRGS(0.652)PAS(0.266)GS(0.082)PDVEGAR 72.913 4.7538999999999995e-06 3192600.0 12224.0 12958.0 17614.0 19230.0 19816.0 17636.0 18294.0 17775.0 21903.0 15306.0 True False 14293.28176499479 14244.384603561395 18033.98456146698 18152.605444501172 15933.197050346245 16711.13711359637 16561.059882909605 17308.425084169263 22223.289938595033 18080.856637770674 0.790520164577618 0.7878158036940054 0.9974076407305957 1.0039682194360535 0.8812191462799392 0.9242447660741374 0.9159444275617875 0.9572790399771318 1.229106030970395 1.0 14.142175411162427 -2.5634168962570447 0.26270492243556753 1.0429106352606958 2.0039970321206315e-14 0.41481928827912296 0.09176115665354448 33.34021628478644 0.747281884931613 0.11924378508813738 13.981282255910774 0.002732644294737513 2.5634168962570447 -1.0429106352606758 GLEPADLAGSAPAEEEGRGS(ph)PASGSPDVEGAR ddPTM_PC-9_Lapatinib_30min_R1 2 GLEPADLAGSAPAEEEGRGSPASGSPDVEGAR 32 1 E7EUN2 E7EUN2 AGAP1 1 GLEPADLAGSAPAEEEGRGS(0.847)PAS(0.06)GS(0.093)PDVEGAR;GLEPADLAGS(0.149)APAEEEGRGS(0.714)PAS(0.099)GS(0.038)PDVEGAR 106.43 6.6513e-16 5523600.0 15793.4 16506.9 17854.7 13706.900000000001 16734.9 15224.1 12998.0 13857.6 17585.7 10150.900000000001 True False 15568.183219845152 16468.67928723091 16386.755487135113 14714.951150877985 15750.586084079301 14573.000732110446 13670.972840297558 14501.474685655974 15605.01328036936 11905.46953977596 1.307649662017288 1.3832868357026447 1.376405645521771 1.2359824282205416 1.3229705919163353 1.2240593017706956 1.148293462481516 1.2180514709820396 1.3107432032170836 1.0 13.539336899724942 -14.522878744944668 0.07893908676079739 0.08689360440761588 1.5599919981854047 0.6860525586224495 0.06156804525833056 151.25340952532088 0.8438140245582473 24.194699263573355 2.3150902180192814 3.0000000023187224e-15 14.522878744944668 1.4730983937777888 GLESDVAELR ddPTM_PC-9_Lapatinib_30min_R1 1 GLESDVAELR 10 0 Q03252 Q03252 LMNB2 Lamin-B2 0 85.73100000000001 0.041339 0.0 19769.0 14513.0 20396.0 16226.0 18750.0 17668.0 15105.0 14168.0 21073.0 12364.0 False True 19487.09043480941 14479.39604017606 18719.119610836795 17419.314168349236 17647.16186391833 16912.380826119606 15887.062990667378 14826.297002826892 18699.53683147235 14501.10092600557 1.34383523942394 0.9985032249661413 1.290875755320538 1.201240806283217 1.216953247478663 1.1662825403683499 1.0955763339441553 1.0224256129572984 1.2895253213456026 1.0 13.823874813596216 -7.083567440559349 3.586444597905497 1.1042827579061116 1.2020591789071011 0.1741738097400628 0.11032213087256304 0.48040727766275276 11.683443265694809 0.04186718300707518 0.03241862826352205 8.249593695490996e-08 7.083567440559349 0.09777642100098949 GLESTTLADKDGEIYCK ddPTM_PC-9_Lapatinib_30min_R1 2 GLESTTLADKDGEIYCK 17 1 E9PP21;P21291;E9PND2 E9PP21 CSRP1 Cysteine and glycine-rich protein 1 0 ; 87.13799999999999 0.0038192 16111500.0 70358.0 49922.0 53509.0 50082.0 53455.0 39109.0 54754.0 46886.0 53900.0 49147.0 False True 69354.68201792285 49806.408676198545 49109.696570713175 53765.197348654445 50310.88199657354 37436.3992375318 57588.894206620425 49064.49472575818 47829.21440783754 57641.99346573892 1.2031971458299007 0.8640646459564646 0.8519777616626472 0.9327435453912823 0.8728164827692362 0.6494639929443651 0.9990788094594603 0.8511935791207671 0.8297633640353909 1.0 15.814832609465382 -4.761244174513778 24.95290390964675 0.8659556249652445 1.203197522146802 0.5250260934411934 0.094229908610323 3.4828373326311124 444077.4594732987 0.02265520416428378 0.12758848406573947 1.7328294706135e-05 4.761244174513778 0.3372418971815576 GLFDEYGSK ddPTM_PC-9_Lapatinib_30min_R1 1 GLFDEYGSK 9 0 P14625;Q58FF3 P14625 HSP90B1;HSP90B2P Endoplasmin;Putative endoplasmin-like protein 0 141.48 0.0032968000000000003 6871500.0 49138.0 45947.0 49565.0 43124.0 43957.0 45709.0 46420.0 43955.0 41504.0 38431.0 False True 48437.28310919442 45840.612544475254 45489.95702643291 46295.48281744684 41371.53568278711 43754.132622883255 48823.40046519562 45997.309765616585 36829.38246350442 45073.74714391139 1.0746229496860764 1.0170135710730999 1.0092339756264916 1.0271052608436282 0.9178632420041789 0.9707232124097678 1.0831892966278651 1.0204900342267185 0.8170916508431312 1.0 15.4599997710543 -1.522878746152301 0.4345001160658205 0.9718336501972933 2.975041481641149 0.1828478220353733 0.06684734110271374 164.35849843466468 2.046941961869085 0.04488042573339207 289.11804714877553 0.0299999999397669 1.522878746152301 2.0032078314438557 GLFIIDDK ddPTM_PC-9_AZD4547_30min_R2 2 GLFIIDDK 8 0 A0A0A0MSI0;Q06830;A0A0A0MRQ5;H7C3T4;Q13162 A0A0A0MSI0;Q13162 PRDX1;PRDX4 Peroxiredoxin-1;Peroxiredoxin-4 0 ; 151.27 0.0019218 48893000.0 118057.0 109296.0 134375.0 132576.0 140378.0 135088.0 121925.0 135303.0 103619.0 109404.0 False True 155596.67026185294 144623.79460022948 132593.0997009346 102012.65147878161 120888.93780066067 126640.92600488695 132776.08879997768 114395.03030363096 109096.08879761881 105573.79925998584 1.4738189906255137 1.3698833954443488 1.2559280866118219 0.9662686404565725 1.1450657137284583 1.199548816965668 1.2576613679782758 1.0835551159992072 1.0333632924297722 1.0 16.68789231322637 -5.352852082923875 2.5868667253224893 1.1143635817016833 1.4401420515657248 0.6779739774068196 0.08875962647203761 0.17859870120816296 2.2826941061179906 0.025643263582234822 0.07166057793991552 4.437597590662286e-06 5.352852082923875 0.3257784698640416 GLFIIDDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLFIIDDK 8 0 A0A0A0MSI0;Q06830;A0A0A0MRQ5;H7C3T4;Q13162 A0A0A0MSI0;Q13162 PRDX1;PRDX4 Peroxiredoxin-1;Peroxiredoxin-4 0 ; 136.16 0.015275 41510000.0 92969.0 82550.0 86103.0 93827.0 105194.0 92486.0 102681.0 89057.0 76365.0 75441.0 False True 108706.81547855049 90745.01844605576 88156.02206744593 88570.17738123829 84581.99084144758 87635.87134770208 92954.3123339367 86719.34811369143 77481.69365661354 89117.8561093726 1.2198095895073682 1.0182585444457526 0.9892071680814871 0.9938544445294761 0.9491026213382171 0.9833705070300197 1.043049242789859 0.9730861120274535 0.8694295064899427 1.0 16.443426906015773 -4.608876128762801 2.00775952504572 0.975943254368382 1.3861502950416427 0.7497050696495458 0.04219826216988084 0.6887991756690203 2.016819386485853 0.011524482671596347 0.6115589272507197 2.4610694602835427e-05 4.608876128762801 0.41020704067326064 GLFIIDDK ddPTM_PC-9_Lapatinib_30min_R1 2 GLFIIDDK 8 0 A0A0A0MSI0;Q06830;A0A0A0MRQ5;H7C3T4;Q13162 A0A0A0MSI0;Q13162 PRDX1;PRDX4 Peroxiredoxin-1;Peroxiredoxin-4 0 ; 151.27 0.0019218 165483000.0 216386.0 184878.0 217781.0 174346.0 192221.0 164357.0 190168.0 169409.0 162489.0 169321.0 False True 213300.29595966704 184449.92634987045 199875.8868389707 187167.9864412069 180914.9387010265 157327.83424487992 200013.9685408295 177280.36059796 144187.77773497417 198587.90924394922 1.0740850073487849 0.9288074337057882 1.0064856798176938 0.9424943701445898 0.9110068150160495 0.7922326935403473 1.0071809975859531 0.8927047032867715 0.7260652387344041 1.0 17.599418263442125 -6.070038471283406 2.08508456358664 0.8827787725653834 0.9973173471510304 0.2653468677728035 0.08567333969038542 0.4616120989850834 3.9820749345729647 0.02744713999128496 0.04092201570496791 8.510626448373009e-07 6.070038471283406 0.11453857458564698 GLFQDEDS(ph)CSDCSYR ddPTM_PC-9_Lapatinib_30min_R1 1 GLFQDEDSCSDCSYR 15 0 Q8NEM2 Q8NEM2 SHCBP1 SHC SH2 domain-binding protein 1 1 GLFQDEDS(0.521)CS(0.47)DCS(0.009)YR 170.09 0.00016013 2708200.0 18117.0 23031.0 28239.0 24588.0 25686.0 25819.0 23265.0 21219.0 29733.0 17648.0 True False 17858.64825774909 22977.673134520428 25917.298425692297 26396.283543163496 24175.19998061898 24714.781557028648 24469.547863480737 22204.91220376793 26384.156437629554 20698.433285518142 0.8628019334315542 1.110116539622203 1.25213817240098 1.275279301532059 1.1679724570039507 1.1940411728804896 1.1821932378138538 1.072782267984689 1.2746934066787308 1.0 14.337233950329376 -4.795750036291113 3.323776738556962 1.1839615657006046 0.8249833820894634 0.5643163706795491 0.0825328897582105 0.20721988607814845 3.658870343345202 0.02000943126779823 0.1887489551485169 1.6004789395637942e-05 4.795750036291113 -0.3589781836111412 GLFQDEDSCS(ph)DCSYR ddPTM_PC-9_Lapatinib_30min_R1 1 GLFQDEDSCSDCSYR 15 0 Q8NEM2 Q8NEM2 SHCBP1 SHC SH2 domain-binding protein 1 1 GLFQDEDS(0.051)CS(0.778)DCS(0.151)Y(0.02)R 123.02 0.00086261 0.0 2639.9 4112.4 4454.0 3549.8 4241.1 3949.2 3736.5 5195.1 3236.9 3533.7 True False 2602.254541901633 4102.877990465104 4087.8093129371973 3810.8641337856616 3991.6468363234153 3780.3019220348415 3929.9576871650866 5436.483311644976 2872.326235931898 4144.495336640723 0.6278821256946722 0.9899584043905931 0.9863225751028419 0.9195001620811372 0.9631201176736762 0.9121259924251539 0.94823551915261 1.311735897874471 0.6930460774169991 1.0 12.016980724223457 -4.7599826105797725 24.97169062737702 0.9754117220159279 0.6278816956774169 0.341385768771699 0.14205645726884586 39.98104094449558 685108.3138777637 0.03321835390877851 0.2029210772234874 1.7378704127647175e-05 4.7599826105797725 -0.34753002633851093 GLFQDEDSCSDCS(ph)YR ddPTM_PC-9_AZD4547_30min_R2 1 GLFQDEDSCSDCSYR 15 0 Q8NEM2 Q8NEM2 SHCBP1 SHC SH2 domain-binding protein 1 1 GLFQDEDS(0.154)CS(0.055)DCS(0.79)Y(0.001)R 120.21 0.0013785 0.0 4033.2 3625.2 5023.8 6901.0 3883.8 4091.9 3741.1 5783.5 4958.3 4919.3 True False 5315.673704228513 4796.9750053501675 4957.181129507393 5310.081069387161 3344.601409267876 3836.0328461402637 4074.050652528986 4889.792966608644 5220.385615429925 4747.076804318384 1.1197783232394471 1.0105113532156023 1.0442597273753562 1.118600201403233 0.7045602056038601 0.8080831644962327 0.8582230329247779 1.0300640095311775 1.0997053198467264 1.0 12.21282367639549 -6.183966113740555 24.99999876834355 0.9099025876538399 1.0667301812737284 0.32178383354105355 0.11088523134734457 159.47307253875826 51459.63646126847 0.03579619267683316 0.046212683734109014 6.546872546994629e-07 6.183966113740555 0.15682759361988852 GLFS(ph)DEEDSEDLFSSQSASK ddPTM_PC-9_Lapatinib_30min_R1 1 GLFSDEEDSEDLFSSQSASK 20 0 E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 E7ESD2 FAM21A WASH complex subunit FAM21A 1 GLFS(1)DEEDSEDLFSSQSASK 126.04 1.7269e-06 0.0 6546.7 7546.9 6739.2 5625.1 8218.4 7652.0 6618.7 8964.0 7269.1 6196.7 True False 6453.342857482255 7529.425616730152 6185.128990064298 6038.788618783518 7735.009869996072 7324.741797683221 6961.383900452177 9380.500164690875 6450.377410983523 7267.791338416269 0.8879372779142705 1.0359991455630997 0.851032824425048 0.8308973576144848 1.0642861785409505 1.0078360063759566 0.9578403639157227 1.2906947555177042 0.8875292520972583 1.0 12.827301284400123 -6.276894335648114 24.650732208283248 1.044046547537581 0.9074736973861799 0.25520689263393836 0.11062342927165587 932.6838449396485 1487631.829767856 0.03368201337251966 0.038333990086092555 5.285738387607806e-07 6.276894335648114 -0.1365728501514012 GLGAGAGAGEES(ph)PATSLPR ddPTM_PC-9_AZD4547_30min_R2 1 GLGAGAGAGEESPATSLPR 19 0 O15173;O15173-2 O15173 PGRMC2 Membrane-associated progesterone receptor component 2 1 GLGAGAGAGEES(0.686)PAT(0.279)S(0.035)LPR 151.73 5.7606000000000004e-05 5668700.0 6656.6 10328.0 11036.0 10111.0 11033.0 10467.0 11164.0 12238.0 8377.5 8182.7 True False 8773.260334118704 13666.324024952151 10889.655429205703 7780.065163392781 9501.258393442627 9812.496835345471 12157.574372466283 10346.898301263338 8820.317546994784 7896.226163620042 1.1110700418561192 1.7307412100119983 1.379096191466395 0.9852890484871818 1.2032657368930724 1.2426818371229265 1.539668965977618 1.3103599221782902 1.117029497917913 1.0 12.946947596703142 -13.97769986907119 0.1802601191848466 3.2164521511515395e-09 1.3669807213538379 0.1655118153550258 0.20542668573254716 211.1075705032395 2.4223467344207115 76.21312393906143 0.6844811547946841 1.0526891117416179e-14 13.97769986907119 1.3669807181373856 GLGAGAGAGEES(ph)PATSLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLGAGAGAGEESPATSLPR 19 0 O15173;O15173-2 O15173 PGRMC2 Membrane-associated progesterone receptor component 2 1 GLGAGAGAGEES(0.84)PAT(0.123)S(0.037)LPR 173.28 1.5919000000000002e-08 3100800.0 11646.0 13350.0 11153.0 10636.0 14127.0 12498.0 5958.7 7320.5 9471.1 6668.6 True False 13617.43778101517 14675.29977292364 11418.929817988037 10040.099402377251 11358.915761518032 11842.582878528427 5394.248798747871 7128.344631710894 9609.596919939166 7877.5643913914455 1.7286355406877059 1.862923493073661 1.4495508066511744 1.2745182271501343 1.4419324549007795 1.5033305080273198 0.6847609909279413 0.904891953596813 1.2198690410503625 1.0 12.943533926575348 -5.960621116698719 0.510071335170569 0.945095693041064 1.9457831073243488 0.6446030665711966 0.20785690850757169 1.0262668433121382 0.4567519208679934 0.1708163303599581 0.5436437304362184 1.0949111623117102e-06 5.960621116698719 1.0006874142832847 GLGAGAGAGEESPAT(ph)SLPR ddPTM_PC-9_AZD4547_30min_R2 1 GLGAGAGAGEESPATSLPR 19 0 O15173;O15173-2 O15173 PGRMC2 Membrane-associated progesterone receptor component 2 1 GLGAGAGAGEES(0.282)PAT(0.543)S(0.175)LPR 104.16 0.00064677 4775300.0 6615.6 10048.0 18354.0 20258.0 14825.0 9991.9 8483.0 14075.0 6565.5 10527.0 True False 8719.223186971682 13295.81950065059 18110.613967709443 15587.83108298002 12766.804648127163 9367.1049134507 9237.970566251473 11900.032161323878 6912.538926266097 10158.45293416943 0.8583219554665956 1.308842949493635 1.782812214130733 1.5344689968044334 1.2567666288224029 0.9220995533624103 0.9093875441582466 1.1714413836871156 0.6804716201435328 1.0 13.310393085385089 -6.642801327567679 3.8814316177134196 0.9453853105470164 1.3962980222740278 0.4193300609391982 0.24368528249934532 0.23477831433645066 6.606853100316911 0.08808817746502383 0.08749713829727064 2.276138435345576e-07 6.642801327567679 0.4509127117270114 GLGAGAGAGEESPAT(ph)SLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLGAGAGAGEESPATSLPR 19 0 O15173;O15173-2 O15173 PGRMC2 Membrane-associated progesterone receptor component 2 1 GLGAGAGAGEES(0.338)PAT(0.523)S(0.14)LPR 185.63 1.7601e-10 4017200.0 9178.1 13210.0 13043.0 7348.1 17670.0 9286.6 12949.0 8469.9 11189.0 10884.0 True False 10731.771054262004 14521.401498151414 13353.994585852954 6936.409779861623 14207.690345156345 8799.594347875032 11722.376977358503 8247.574099600857 11352.617957491657 12857.183042303406 0.8346906953841868 1.12943880867001 1.0386407770594002 0.5394968522295334 1.105039128587454 0.6844107545892538 0.9117375819251307 0.6414759805833236 0.8829786369330399 1.0 13.650286968088476 GLGHPPS(ph)SPLLK ddPTM_PC-9_AZD4547_30min_R2 1 GLGHPPSSPLLK 12 0 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 GLGHPPS(0.868)S(0.132)PLLK 76.357 0.010622 7781400.0 47550.0 49181.0 58924.0 72477.0 58549.0 64638.0 47662.0 56746.0 47398.0 50558.0 True False 62669.91089855848 65077.79646312664 58142.629259742374 55768.54740848764 50420.481979305034 60596.175641832524 51903.82566647155 47977.2095933559 49903.3615150652 48787.97980865753 1.2845358865922456 1.3338899605672634 1.1917408650198884 1.1430796607526552 1.0334611553306787 1.2420308420124335 1.063865031305541 0.983381762916165 1.0228618137250631 1.0 15.574238125564523 -4.515735742024084 0.28758080410890335 0.9802813372605805 1.6669421662887216 0.71637990260222 0.06425139346295168 5.345469855017922 0.32400430385178497 0.08003229186637635 1.3315212711139208 3.0497501263769356e-05 4.515735742024084 0.6866608290281411 GLGHPPS(ph)SPLLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLGHPPSSPLLK 12 0 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 GLGHPPS(0.5)S(0.5)PLLK 92.11200000000001 0.0060382 7796900.0 45241.0 43759.0 39812.0 55505.0 76430.0 60699.0 63409.0 63657.0 70187.0 54039.0 True False 52899.40774951975 48103.10432684389 40761.2690678508 52395.23479963794 61454.0901573458 57515.837585517475 57402.44047859491 61986.07120016673 71213.35209424159 63835.84292751139 0.8286787692235774 0.7535438105120227 0.6385326361890004 0.8207808089749077 0.9626894130172264 0.9009959757377908 0.8992195895929201 0.9710229920603514 1.1155700125258425 1.0 15.962079084005408 -6.665313310939536 0.712763627555026 1.0263419925050477 0.732886701939349 0.6817174485857032 0.07256401252964771 0.4507054585926447 0.5080669494261423 0.055440585571500604 0.06210617202914901 2.1611588469648886e-07 6.665313310939536 -0.29345529056569863 GLGHPPS(ph)SPLLK ddPTM_PC-9_Lapatinib_30min_R1 1 GLGHPPSSPLLK 12 0 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 GLGHPPS(0.609)S(0.391)PLLK 104.43 0.001911 8273100.0 94263.0 85228.0 93360.0 86845.0 125850.0 148740.0 148170.0 157220.0 163560.0 134790.0 True False 92918.79233428277 85030.6598023925 85684.30118002155 93231.87100642736 118447.75043061988 142378.73692987475 155841.5175986221 164525.0151598282 145138.15043684424 158088.27190361454 0.587765247955489 0.5378682351226862 0.5420028959027571 0.5897456521206726 0.7492507129361041 0.9006280808527163 0.9857879760595886 1.0407161339592486 0.9180829715523369 1.0 17.27037081686995 -6.595477038476155 1.5499056875490522 0.9911727315390357 0.5507940637264923 0.9731472795077295 0.0320041229219101 0.05429979857779013 0.2685679481204892 0.013109266520901096 0.013620917127643612 2.5381831783501806e-07 6.595477038476155 -0.4403786678125434 GLGHPPSS(ph)PLLK ddPTM_PC-9_AZD4547_30min_R2 2 GLGHPPSSPLLK 12 0 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 GLGHPPS(0.328)S(0.672)PLLK;GLGHPPS(0.237)S(0.763)PLLK 132.86 7.4667e-05 21904100.0 140329.0 163511.0 222297.0 268243.0 222467.0 233371.0 160422.0 193556.0 172955.0 221084.0 True False 184950.70297547404 216362.73311812055 219349.19653372053 206403.72066303747 191581.29710994312 218778.27447801782 174699.24722140678 163646.36767440182 182097.04820536956 213343.91645273237 0.8669134140342407 1.0141500011604831 1.028148353985611 0.9674694460236342 0.8979927822426992 1.0254722896047024 0.8188620989345738 0.7670542961587501 0.8535375708531827 1.0 17.702821446805658 -7.271324119186039 24.876127846813226 0.8404513424009046 0.9685545205487451 0.317225531400252 0.07460650581721005 657.8695186143183 1655600.0242933556 0.030117550157616465 0.020576852107182995 5.353969352123265e-08 7.271324119186039 0.12810317814784056 GLGHPPSS(ph)PLLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLGHPPSSPLLK 12 0 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 GLGHPPS(0.246)S(0.754)PLLK;GLGHPPS(0.046)S(0.954)PLLK 79.88600000000001 0.008441500000000001 28226000.0 67797.0 77267.0 85286.0 98516.0 113007.0 114908.0 133937.0 121392.0 116349.0 116682.0 True False 79273.69304821258 84937.55712018654 87319.54168895617 92996.46791318136 90864.08957753712 108882.02219602703 121249.51774009313 118205.58862545561 118050.38401431733 137835.52294579626 0.5751325300908599 0.6162239987553004 0.6335053535023373 0.674691588392291 0.6592211328081903 0.7899416628530863 0.8796681374203835 0.8575843592361883 0.8564583460878991 1.0 17.072588221501206 -6.983290945711815 0.4155500731232712 0.9877917094320168 0.5445833204474705 0.942557398241529 0.03211913635481527 0.2972331865422488 0.11226782430974554 0.03623765290998057 0.04944808532333694 1.0392237282701946e-07 6.983290945711815 -0.4432083889845463 GLGHPPSS(ph)PLLK ddPTM_PC-9_Lapatinib_30min_R1 1 GLGHPPSSPLLK 12 0 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 GLGHPPS(0.231)S(0.769)PLLK 75.911 0.010898 22840000.0 205470.0 188060.0 236680.0 173920.0 243050.0 333920.0 321360.0 290100.0 351270.0 289080.0 True False 202539.96012141643 187624.55862437203 217221.08401122037 186710.65698011246 228754.27685468533 319639.02000553877 337998.4483734441 303579.10506211733 311706.2735629147 339047.09282511304 0.5973800230338221 0.553387899778136 0.640681157892326 0.5506923991718796 0.6746976502543885 0.9427569997493377 0.9969070831932783 0.8953891995726659 0.919359818028874 1.0 18.371126148584985 -6.6855241211182825 3.522255014205004 0.9498461431880358 0.5892256203113377 0.95439725830542 0.03834212909355386 0.04574104410410188 1.1267175474397197 0.013448028750938762 0.013106125892365305 2.0628890893557421e-07 6.6855241211182825 -0.3606205228766981 GLGKPGGQGDAIQLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 GLGKPGGQGDAIQLSPK 17 1 Q5VV41 Q5VV41 ARHGEF16 Rho guanine nucleotide exchange factor 16 1 GLGKPGGQGDAIQLS(1)PK 100.53 0.00054268 39637000.0 201940.0 229130.0 189460.0 222340.0 236450.0 220180.0 224460.0 196870.0 204180.0 235830.0 True False 266152.7193870634 303191.79161863733 186947.63660903528 171082.94811875693 203622.99892409175 206412.10979329012 244436.50516336277 166448.265122546 214972.53795826822 227573.66348106583 1.1695233768085267 1.332279785722494 0.8214818610791901 0.7517695391540378 0.8947564309919949 0.9070122905960234 1.0740983882948298 0.7314039005062399 0.944628366349404 1.0 17.79597408232849 -5.263283117697217 24.99995520773552 0.883374739949471 1.250901598572319 0.6493478228894057 0.10578652694795504 87.73353541879796 1189631.591231647 0.02732933806123462 0.061977196927959305 5.4540219607063304e-06 5.263283117697217 0.36752685862284806 GLGKPGGQGDAIQLS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLGKPGGQGDAIQLSPK 17 1 Q5VV41 Q5VV41 ARHGEF16 Rho guanine nucleotide exchange factor 16 1 GLGKPGGQGDAIQLS(1)PK;GLGKPGGQGDAIQLS(1)PK 120.32 4.1079e-05 55800000.0 670350.0 573170.0 533540.0 791140.0 775810.0 639680.0 828040.0 669530.0 563910.0 604970.0 True False 783827.0149839871 630070.5296514335 546261.6170617166 746814.9907104864 623795.5996986834 606134.054707719 749602.0567095483 651955.5469256744 572156.1169370915 714646.2720601158 1.0968041751962736 0.881653699578009 0.7643804192625316 1.0450134841641832 0.8728732298574278 0.8481595418673522 1.0489134079558902 0.9122772655712281 0.8006144288526588 1.0 19.44686980329203 -4.756834743526347 24.95774850720639 0.9066648001501593 1.0968044674907633 0.27390886006492576 0.09208681182732899 186.60747301710725 1011310.9817636374 0.02250970738114319 0.176357623988393 1.7505126618984502e-05 4.756834743526347 0.19013966734060406 GLGKPGGQGDAIQLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 GLGKPGGQGDAIQLSPK 17 1 Q5VV41 Q5VV41 ARHGEF16 Rho guanine nucleotide exchange factor 16 1 GLGKPGGQGDAIQLS(1)PK 123.19 0.00063123 0.0 22490.0 16996.0 12194.0 17598.0 14602.0 14702.0 14859.0 16890.0 11059.0 11701.0 True False 22169.288475839126 16956.646806231136 11191.45639020121 18892.215625207067 13743.139068636552 14073.229732035914 15628.326314354617 17674.771059976436 9813.41896356726 13723.502259397541 1.6154249882283587 1.235591796155359 0.8154956496281812 1.3766322377562266 1.0014308890593555 1.025483835396237 1.1388001414618996 1.287919856454511 0.7150812364130485 1.0 13.744361086095333 -4.842814065843252 3.5351994123666914 1.066013686892784 1.6460127656525299 0.45897659381163536 0.18713432118078316 0.2235648288229971 4.665109298144353 0.044779505460697366 0.31185772887877 1.4361041398991655e-05 4.842814065843252 0.5799990787597458 GLGLDDALEPR ddPTM_PC-9_Lapatinib_30min_R1 4 GLGLDDALEPR 11 0 Q9Y230;M0R0Z0;A0A1W2PS48;X6R2L4 Q9Y230 RUVBL2 RuvB-like 2 0 ;;; 128.27 0.001467 4110800.0 65675.0 62876.0 73507.0 63922.0 67059.0 72558.0 70302.0 60701.0 80884.0 63367.0 False True 64738.462456680085 62730.41448508996 67463.53820522541 68623.0371175411 63114.72146306668 69454.86348095922 73941.89356967207 63521.390059895195 71773.99217372035 74319.90151877984 0.8710784209034692 0.8440594403806989 0.9077452583569168 0.9233467175706739 0.8492304237932591 0.9345392292185523 0.9949137722012152 0.8547022905277132 0.965743908522051 1.0 16.181460969557662 -1.5228790306847433 0.05188641808554954 1.1668776975860136 0.42979274721673677 0.4458941084262428 0.041852064242267714 441.58934852827116 1.7329767815723915 5.643627715518716 25.75140530683362 0.029999980284968576 1.5228790306847433 -0.7370849503692768 GLGLGANLTEAQALT(ph)PTGPSR ddPTM_PC-9_AZD4547_30min_R2 2 GLGLGANLTEAQALTPTGPSR 21 0 Q92917 Q92917 GPKOW G patch domain and KOW motifs-containing protein 1 GLGLGANLT(0.12)EAQALT(0.875)PT(0.005)GPSR;GLGLGANLT(0.014)EAQALT(0.973)PT(0.01)GPS(0.002)R 148.69 3.4899000000000002e-06 20667000.0 18172.8 20977.3 28545.9 41151.0 30937.6 30701.8 25256.3 32731.0 23016.8 27360.6 True False 23951.3723822781 27757.80199154035 28167.362714440285 31664.272726612235 26642.448261848145 28782.011592568037 27504.0617720638 27673.17603355536 24233.42105827149 26402.71372191848 0.9071557050741578 1.0513238254178747 1.0668358946397567 1.1992809928596777 1.009079920437521 1.0901156561294818 1.0417134413433806 1.0481186261767552 0.9178382689561896 1.0 14.688398599737264 -8.176962202482068 6.648341816849924 0.9596132414603389 1.057091534450252 0.2138837418903471 0.0706288277355518 0.3358108626027244 21.752081114637956 0.049128668788926924 0.01817074513082346 6.6533105877561675e-09 8.176962202482068 0.09747829298991317 GLGLGANLTEAQALT(ph)PTGPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLGLGANLTEAQALTPTGPSR 21 0 Q92917 Q92917 GPKOW G patch domain and KOW motifs-containing protein 1 GLGLGANLTEAQALT(0.633)PT(0.324)GPS(0.043)R;GLGLGANLT(0.018)EAQALT(0.935)PT(0.039)GPS(0.008)R 178.56 2.3858e-12 8877300.0 11222.2 9115.4 13124.2 11155.5 14495.1 11926.3 13545.4 13545.7 12545.0 12373.9 True False 13121.896811446708 10020.316670420088 13437.130701805669 10530.493501618977 11654.889208945984 11300.863832948764 12262.281651796426 13190.13972785551 12728.44689219169 14617.190118261493 0.8977030951422947 0.685515929487812 0.9192690656064221 0.7204184536440462 0.7973412888969229 0.7731214919911599 0.8388945859352926 0.902371770575581 0.870786162676357 1.0 13.83537838632143 -8.359729233068071 0.7926296984084757 0.9942673150170356 0.7944545079589157 0.42851594629544554 0.06949422159902943 0.546588848919115 0.7673984388631777 0.061910634385792904 0.023614262099399805 4.367880689599069e-09 8.359729233068071 -0.19981280705811988 GLGLGANLTEAQALT(ph)PTGPSR ddPTM_PC-9_Lapatinib_30min_R1 2 GLGLGANLTEAQALTPTGPSR 21 0 Q92917 Q92917 GPKOW G patch domain and KOW motifs-containing protein 1 GLGLGANLT(0.007)EAQALT(0.989)PT(0.003)GPSR;GLGLGANLT(0.007)EAQALT(0.942)PT(0.05)GPS(0.001)R 146.15 0.00035539 16002400.0 35712.2 24387.5 33208.0 27081.7 31447.0 27283.1 29887.0 26659.1 35518.0 31318.6 True False 35202.93747918458 24331.03224211352 30477.76642658699 29073.37855990286 29597.349287180776 26116.26541301245 31434.402621785892 27897.77910982937 31517.58881887892 36731.97828058867 0.9583730342612086 0.6623937337720649 0.8297338682325538 0.7915004832524072 0.8057651853404735 0.7109953407223323 0.8557775565929067 0.7594956878369982 0.8580422371515629 1.0 15.16474897719097 -8.609999274422037 3.815595464351866 0.9999505199041223 0.7929364265648733 0.39603644313367714 0.0760113876949572 0.3659677045690289 12.920994798028566 0.06663595060900797 0.017490653997121526 2.454713016782917e-09 8.609999274422037 -0.20701409333924903 GLGLGANLTEAQALTPT(ph)GPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLGLGANLTEAQALTPTGPSR 21 0 Q92917 Q92917 GPKOW G patch domain and KOW motifs-containing protein 1 GLGLGANLT(0.038)EAQALT(0.106)PT(0.749)GPS(0.106)R 99.161 0.00058076 5474800.0 3241.2 2405.7 5941.0 6445.1 7169.5 5097.5 8242.0 4748.8 5818.1 2961.8 True False 3789.871143381966 2644.5219972825794 6082.655971367964 6084.001942296128 5764.687941686384 4830.178126364115 7461.25809308741 4624.149031769508 5903.178705736189 3498.7508944041006 1.083206909484034 0.7558474658805306 1.7385221626085354 1.738906863025566 1.6476417200511249 1.380543591739983 2.13254910631704 1.3216571203069554 1.6872246364203087 1.0 11.772624235264049 -5.263350431690175 24.99921760644012 1.6129440818262264 0.9195271570972536 0.4410455045181423 0.29605542262690504 126.19537343731668 1650836.2636898067 0.07157641709387336 0.16218205783937645 5.453176673555346e-06 5.263350431690175 -0.6934169247289728 GLGPPS(ph)PPAPPR ddPTM_PC-9_AZD4547_30min_R2 3 GLGPPSPPAPPR 12 0 Q13425;Q13425-2;A0A140TA73 Q13425 SNTB2 Beta-2-syntrophin 1 GLGPPS(1)PPAPPR;GLGPPS(1)PPAPPR;GLGPPS(1)PPAPPR 115.92 0.00070057 293831000.0 96306.0 119640.0 173436.0 281683.0 205324.0 188953.0 148671.0 218160.0 184756.0 214528.0 True False 126929.30471075834 158311.29031228452 171136.1253189309 216745.33630896712 176818.30675022304 177137.73903974707 161902.43098611012 184448.38481807619 194521.82497315053 207017.44001724126 0.6131333896322317 0.764724413069255 0.8266749183289968 1.046990709048067 0.8541227576550888 0.8556657788106853 0.7820714572290443 0.8909799329115198 0.9396397953570963 1.0 17.659392785961117 -4.961957889409913 1.8460007132292817 0.895502195011335 0.5814916302844252 0.6030286748163773 0.07429794127654321 0.4189764686230957 1.9730132838528207 0.021267492258534727 0.20357068358656907 1.0915461711458869e-05 4.961957889409913 -0.3140105647269098 GLGPPS(ph)PPAPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 GLGPPSPPAPPR 12 0 Q13425;Q13425-2;A0A140TA73 Q13425 SNTB2 Beta-2-syntrophin 1 GLGPPS(1)PPAPPR;GLGPPS(1)PPAPPR;GLGPPS(1)PPAPPR;GLGPPS(1)PPAPPR;GLGPPS(1)PPAPPR;GLGPPS(1)PPAPPR 134.99 5.9046000000000004e-05 286245300.0 205746.0 245216.0 300039.0 314905.0 367238.0 305662.0 319828.0 279576.0 283281.0 233185.0 True False 240574.73413126852 269559.4239039138 307193.06766424386 297261.8937857853 295280.3501400406 289632.54663280194 289531.5764857995 272237.42623525736 287423.44871000067 275459.59460855526 0.8733576133847861 0.9785806309886358 1.1152019159135982 1.0791488102210143 1.0719552192750876 1.051452018015155 1.0510854664446936 0.9883025734577269 1.0434323375754864 1.0 18.071481189120938 -4.914172986179852 3.448950489973704 1.0516175729590862 0.872291312171912 0.7068386751920279 0.035137330456462224 0.14237991577771394 3.041458325105151 0.009495014848550167 0.05529097015929031 1.218504153283023e-05 4.914172986179852 -0.17932626078717417 GLGPPS(ph)PPAPPR ddPTM_PC-9_Lapatinib_30min_R1 4 GLGPPSPPAPPR 12 0 Q13425;Q13425-2;A0A140TA73 Q13425 SNTB2 Beta-2-syntrophin 1 GLGPPS(1)PPAPPR;GLGPPS(1)PPAPPR;GLGPPS(1)PPAPPR;GLGPPS(1)PPAPPR 107.53 0.0015407 312481000.0 236412.0 284528.0 281651.0 252197.0 266921.0 251104.0 237224.0 236136.0 292420.0 197715.0 True False 233040.72152734885 283869.1928973475 258494.74198430034 270744.40868452954 251221.23156687716 240364.86727201345 249506.29797405362 247107.74061685055 259484.58028088792 231889.77431132217 1.0049633375143205 1.2241557168288097 1.1147310947711728 1.1675564801794291 1.083364854327736 1.0365479374235498 1.075969385519693 1.0656258619023777 1.1189996671975648 1.0 17.82307967701834 -6.449233049556854 6.086562165794241 1.064034543847023 1.133397031276359 0.22932336441377987 0.05855029568642784 0.3287804775326201 21.38137257456995 0.017341076444002797 0.019544177958439712 3.5544053215258953e-07 6.449233049556854 0.06936248742933615 GLGPS(ph)PAGDGPSGSGK ddPTM_PC-9_AZD4547_30min_R2 2 GLGPSPAGDGPSGSGK 16 0 Q92934;F5GYS3;A8MXU7 Q92934 BAD Bcl2-associated agonist of cell death 1 GLGPS(0.953)PAGDGPS(0.037)GS(0.011)GK;GLGPS(0.939)PAGDGPS(0.056)GS(0.006)GK 103.13 0.0014062 29220000.0 77360.0 72467.0 100781.0 129748.0 106648.0 98113.0 73760.0 117892.0 86157.0 96056.0 True False 101958.87081203941 95890.54058057774 99444.57809086444 99836.60318661713 91841.76607847997 91977.97860000478 80324.49710794636 99674.50028865304 90711.08312699839 92693.10867717087 1.0999617152461583 1.0344948178892437 1.0728367999524906 1.0770660797915996 0.9908154704180229 0.9922849703999385 0.8665638498294238 1.0753172669588285 0.9786173365155394 1.0 16.500174464389076 -6.305593509227407 5.1228080775688785 0.9814983959287452 1.0687433750507227 0.4236989360121378 0.04976470340793666 0.20805347645163302 13.340095824627847 0.01558504783476428 0.018091529771944614 4.947735682925965e-07 6.305593509227407 0.08724497912197748 GLGPS(ph)PAGDGPSGSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLGPSPAGDGPSGSGK 16 0 Q92934;F5GYS3;A8MXU7 Q92934 BAD Bcl2-associated agonist of cell death 1 GLGPS(1)PAGDGPSGSGK;GLGPS(0.998)PAGDGPS(0.002)GSGK 145.46 7.2589999999999994e-06 16344100.0 70011.0 71546.0 76209.0 78445.0 91794.0 75128.0 80722.0 72415.0 58211.0 53604.0 True False 81862.4795197194 78648.61404895851 78026.11158424187 74049.98097212144 73807.62464874257 71188.15542471467 73075.42778332952 70514.18298003482 59062.2257506075 63321.980870969484 1.2927971992305436 1.242042857269736 1.2322121088289204 1.169419843687649 1.1655924788445826 1.1242250233733844 1.154029403032014 1.1135814453391912 0.9327286502764017 1.0 15.95041876686321 -6.884387492546602 0.34292820481116815 0.9674514805496269 1.3160290400432857 0.8201250496228942 0.04395645916440888 0.7654465908106404 0.19579852187012975 0.054413458771606214 0.09822319135238464 1.3050059970775962e-07 6.884387492546602 0.34857755949365876 GLGPS(ph)PAGDGPSGSGK ddPTM_PC-9_Lapatinib_30min_R1 1 GLGPSPAGDGPSGSGK 16 0 Q92934;F5GYS3;A8MXU7 Q92934 BAD Bcl2-associated agonist of cell death 1 GLGPS(1)PAGDGPSGSGK 99.238 0.0019408000000000001 12397000.0 70310.0 66261.0 81278.0 56207.0 65906.0 66430.0 53225.0 63264.0 72731.0 54829.0 True False 69307.3665067252 66107.57672556378 74595.63658215287 60340.65028105544 62029.538656181416 63588.94375589351 55980.73006807485 66203.47639658669 64539.268888616476 64306.11959494984 1.0777724879572443 1.028013774458184 1.1600083639319936 0.9383344953968296 0.96459775596618 0.9888474713826045 0.8705350349342365 1.0295050737563995 1.0036256159621384 1.0 15.972668415534828 -5.7768122336697045 24.999727521099473 0.9683258928914025 1.0825397830339059 0.5283511663137355 0.050879270242968774 181.751343650525 295568.1151495151 0.014266293898603318 0.021246420208054714 1.671813263123868e-06 5.7768122336697045 0.11421389014250338 GLGTDDNTLIR ddPTM_PC-9_Lapatinib_30min_R1 1 GLGTDDNTLIR 11 0 P09525-2;P09525;Q6P452 P09525-2 ANXA4 Annexin A4;Annexin 0 95.48299999999999 0.028567000000000002 3065700.0 13924.0 18317.0 16669.0 18904.0 15288.0 21576.0 12779.0 15652.0 17103.0 16457.0 False True 13725.441206651134 18274.58811189312 15298.539164200753 20294.263221895366 14388.789897364442 20653.244776112555 13440.634091872786 16379.249060435246 15176.680037425696 19301.570522425896 0.7111048912161821 0.9467928058320666 0.7926059253274678 1.0514306697642086 0.7454724930619793 1.0700292368497264 0.6963492466199334 0.8485967005329802 0.7862924946854652 1.0 14.236430620448619 -10.160343921826584 18.202769325457645 0.999999999997202 0.855802954987218 0.11105767815071721 0.1264340064770981 0.0 0.0 0.11302245464652261 0.027411971680834965 6.912833204324368e-11 10.160343921826584 -0.14419704500998398 GLGTDEDS(ph)LIEIICSR ddPTM_PC-9_Lapatinib_30min_R1 3 GLGTDEDSLIEIICSR 16 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YN28;H0YNP5;H0YL33;H0YMM1;H0YNA0;H0YN52;H0YLE2 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 GLGT(0.016)DEDS(0.982)LIEIICS(0.002)R;GLGTDEDS(1)LIEIICSR;GLGTDEDS(1)LIEIICSR 151.49 1.9309e-10 4648800.0 17387.8 17579.5 20598.0 17261.3 18238.4 20142.4 18898.300000000003 17588.5 18891.199999999997 16569.5 True False 17139.84678346801 17538.79574783126 18904.511950579337 18530.7535840088 17165.653170074038 19280.956506227718 19876.76150390792 18405.72591997606 16763.474122844887 19433.515997529074 0.8819735340556645 0.9025024473214871 0.9727787783221009 0.9535461100484822 0.8833014659959942 0.992149671149536 1.0228083022359518 0.9471124999879746 0.8626063407659388 1.0 14.24625932284536 -6.7721162770860595 24.99992161814168 0.9652469477807484 0.9228407928671866 0.18415665272077275 0.048158652446948544 446.07058103266274 1044466.2855991354 0.017926754664332117 0.01596884018374859 1.689988397146497e-07 6.7721162770860595 -0.04240615491356181 GLGTDEDSLIEIICSR ddPTM_PC-9_AZD4547_30min_R2 4 GLGTDEDSLIEIICSR 16 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YN28;H0YNP5;H0YL33;H0YMM1;H0YNA0;H0YN52;H0YLE2 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ;;; 305.3 7.499699999999998e-128 33901000.0 30341.8 31613.6 37276.4 49624.0 48434.4 42783.4 34296.2 47831.0 37154.2 37989.5 False True 39989.86125135397 41832.07796235739 36782.09058003294 38183.953483157275 41710.11959860032 40108.14723467275 37348.49535945702 40439.81799703601 39118.09516019735 36659.499168103845 1.090845815104527 1.1410979121818998 1.0033440558303033 1.0415841555298662 1.1377711246773072 1.0940724271969722 1.0187944791115053 1.103119761991219 1.0670657277891196 1.0 15.161899455862914 -14.522878744620838 0.2758634946485522 0.4490957430613925 1.082543638469606 0.22609607039978508 0.043578775137703585 362.1447415211211 3.485700482119254 113.9871068891825 0.053193296073247284 3.0000000045556597e-15 14.522878744620838 0.6334478954082137 GLGTDEDSLIEIICSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GLGTDEDSLIEIICSR 16 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YN28;H0YNP5;H0YL33;H0YMM1;H0YNA0;H0YN52;H0YLE2 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ;;; 206.46 2.454e-16 31943700.0 38164.3 37810.9 41155.9 45883.0 53133.6 41475.6 35608.6 43019.4 38238.2 38744.0 False True 44624.76221071588 41564.51626846733 42137.2127406199 43312.32426469304 42722.452502739034 39300.54652237906 32235.49562406118 41890.186332822 38797.36133543283 45767.98050266476 0.9750214390193093 0.908157096117608 0.9206701339633401 0.9463455408999585 0.9334572343704699 0.8586908596522159 0.7043241862547185 0.9152727708923714 0.8476965972569824 1.0 15.482051014440422 -6.777181949161961 5.963538030924251 0.8492972390590535 0.9350443665406419 0.18562172788009645 0.07125441633381836 0.2359232939809165 28.396384363881957 0.02424306346073948 0.022246622860986602 1.670390651805403e-07 6.777181949161961 0.08574712748158841 GLGTDEDSLIEIICSR ddPTM_PC-9_Lapatinib_30min_R1 4 GLGTDEDSLIEIICSR 16 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YN28;H0YNP5;H0YL33;H0YMM1;H0YNA0;H0YN52;H0YLE2 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ;;; 262.15 6.2143e-58 150646200.0 82179.0 67803.1 99113.4 72074.1 75198.3 77013.7 71710.6 69549.3 80400.5 71595.3 False True 81007.11239021712 67646.1060877601 90964.67884078785 77374.66974614933 70775.28383954604 73720.00357870318 75423.42398533944 72780.81438020237 71344.94903520106 83970.45221025958 0.9647097313156974 0.8055941620794921 1.08329390215757 0.921451149892648 0.8428593865652502 0.8779279096188553 0.8982138597572557 0.8667431514833493 0.8496435014611494 1.0 16.35759413661983 -6.0069604254221 24.99801710671757 0.8824253988230547 0.9475943680339938 0.1181589034722883 0.07473332754853677 651.4717877981121 2339746.5923807123 0.0206883043660238 0.029386953465009125 9.841007767104564e-07 6.0069604254221 0.06516896921093907 GLGTDEDTLIEILASR ddPTM_PC-9_Lapatinib_30min_R1 1 GLGTDEDTLIEILASR 16 0 P04083;Q5T3N1 P04083;Q5T3N1 ANXA1 Annexin A1;Annexin 0 199.8 3.9238999999999996e-50 0.0 4283.7 9333.6 8248.7 8003.5 8777.4 10059.0 3047.9 4208.1 2941.2 7818.2 False True 4222.613652465628 9311.988622654677 7570.523726902796 8592.104088893331 8261.130589032353 9628.80001867427 3205.705348510765 4403.623688424327 2609.931083790941 9169.56545290333 0.46050313661577436 1.0155321613093726 0.8256142306619082 0.937024129771912 0.9009293440854013 1.050082478622314 0.3496027554387272 0.48024344349164566 0.28462974578196254 1.0 13.162637650565726 -7.264970846246284 24.997736913510124 0.485305934959167 0.8749161969768205 0.32270612678995736 0.2351129491857548 314.87342170210724 2228839.572696496 0.0901343122770147 0.06349011199548386 5.432868005672889e-08 7.264970846246284 0.38961026201765353 GLHSENREDEGWQVYR ddPTM_PC-9_AZD4547_30min_R2 1 GLHSENREDEGWQVYR 16 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 0 52.821000000000005 0.035651 2794700.0 34472.0 26471.0 36906.0 59547.0 53780.0 40772.0 38240.0 42759.0 36281.0 48823.0 False True 45433.37893785716 35027.233081381506 36416.60232604797 45819.35914197902 46313.5753103729 38222.52039464085 41643.28591930409 36151.57905407088 38198.73959087048 47113.721630564636 0.9643343248091578 0.7434613923315682 0.7729510865561298 0.9725268468762631 0.9830167031493294 0.8112821291078883 0.8838886948019907 0.7673259042779129 0.8107773758651526 1.0 15.523859678141818 -12.05116094794619 2.224004893689892 3.172594968310771 0.8547984181204616 0.20036564171395121 0.0858616062191403 4154650.686028209 476631.5108067169 45471044.1263204 0.022251720844487906 8.888716442313142e-13 12.05116094794619 -2.3177965501903093 GLHSENREDEGWQVYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLHSENREDEGWQVYR 16 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 0 ; 89.74700000000001 0.0016579999999999998 7005800.0 34890.0 23809.8 29302.1 41082.0 48495.0 42912.0 43140.4 50227.0 44010.0 36065.3 False True 40796.187891088746 26173.479590513656 30000.773192833076 38780.30872964104 38992.75287427031 40661.619177741406 39053.82900255131 48908.59446990549 44653.56299126001 42603.653397242284 0.9575748706501651 0.6143482425431583 0.7041831110844361 0.9102578215076567 0.9152443456127237 0.9544162515502348 0.9166779345988963 1.1479906198155139 1.048115817085077 1.0 15.378689530941553 -6.526772939261982 0.8672613032635387 1.0516410099796192 0.7484917635917069 0.53118572599437 0.10096040710638085 0.45041677048463996 0.7453958096521889 0.05863578752324356 0.07090603719789655 2.973220104215297e-07 6.526772939261982 -0.3031492463879123 GLHSENREDEGWQVYR ddPTM_PC-9_Lapatinib_30min_R1 1 GLHSENREDEGWQVYR 16 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 0 83.243 0.0025597 3165100.0 12935.0 10426.0 14219.0 9891.4 14642.0 10911.0 10075.0 6210.7 15939.0 11382.0 False True 12750.54452801152 10401.859237571529 13049.968706927268 10618.846552743113 13780.786347279573 10444.361964783286 10596.634202646399 6499.2717952750545 14143.78197488909 13349.36353443833 0.9551425051177914 0.7792026346976837 0.9775723519148541 0.7954571411100535 1.0323178563328708 0.7823865113748083 0.7937932153326627 0.4868600498074989 1.0595098364353732 1.0 13.704483338870626 GLHVVEVTYDDVPIPNS(ph)PFK ddPTM_PC-9_AZD4547_30min_R2 2 GLHVVEVTYDDVPIPNSPFK 20 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 1 GLHVVEVTYDDVPIPNS(1)PFK;GLHVVEVTYDDVPIPNS(1)PFK 133.86 3.7907999999999998e-06 12210600.0 85811.0 85091.0 97125.0 102221.0 103905.0 108082.0 89904.0 101304.0 75450.0 89519.0 True False 113097.11302031971 112595.00170480271 95837.0590396524 78655.52774870674 89479.58428085354 101323.61545407551 97905.28183287426 85649.79453433413 79438.13296577214 86384.96705746294 1.3092221583541028 1.3034096734667382 1.1094182506998234 0.9105233286294523 1.0358235620016163 1.1729311118064725 1.133360180223812 0.9914895780114175 0.9195828356678102 1.0 16.39849265213916 -5.345554531216805 3.61649836533875 1.0331307137320378 1.3102783842808272 0.6680062936185149 0.07830867532365177 0.14916881152886535 3.669327671561882 0.023174535518127582 0.05527502944575297 4.512793578985394e-06 5.345554531216805 0.2771476705487894 GLHVVEVTYDDVPIPNS(ph)PFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLHVVEVTYDDVPIPNSPFK 20 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 1 GLHVVEVTYDDVPIPNS(0.999)PFK;GLHVVEVTYDDVPIPNS(1)PFK 133.96 3.2774e-05 8368800.0 61457.0 54552.0 51516.0 56210.0 59309.0 55761.0 57460.0 54297.0 45716.0 42606.0 True False 71860.45626892068 59967.562038391836 52744.33681551799 53060.7359352788 47687.82720321889 52836.79499836964 52016.97282562514 52871.76128242692 46384.51001382506 50330.13053108955 1.427782036538363 1.1914843336507766 1.0479674155213479 1.0542538907683245 0.9475005667581475 1.0498044499553143 1.033515555726477 1.0504991885480484 0.9216051999939234 1.0 15.619134719015724 -4.599544432385415 1.197541776953586 1.008027387616536 1.7696510967479562 0.9094501591816029 0.04120301060218565 0.5790966643650349 0.5358324071481196 0.012233249181080538 0.6098199877920053 2.51452274065226e-05 4.599544432385415 0.7616237091314202 GLIVYCVT(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 2 GLIVYCVTSPK 11 0 E9PCH4;Q8TEU7;A0A5F9ZHG7;Q8TEU7-4 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 1 GLIVYCVT(0.615)S(0.385)PK;GLIVYCVT(0.601)S(0.398)PK 93.667 0.017059 24380000.0 244023.0 202300.0 266920.0 334630.0 350890.0 314290.0 312130.0 287950.0 269610.0 332830.0 True False 321617.23800628615 267689.5188078834 263380.4663975704 257486.22348196304 302174.980302282 294637.3966161015 339908.96532406815 243453.94393273286 283861.0341802764 321177.72300556704 1.0013684479627234 0.8334622846904094 0.8200458734586806 0.8016939066396581 0.9408341820053453 0.9173656063655277 1.0583204904226078 0.7580038293269581 0.8838129603881529 1.0 18.29301230495097 -6.2858907455797315 24.378385168309222 0.9204350589449359 0.8588013912350634 0.10173135041910764 0.08900803119401372 1449.6582969738442 1445326.3230748023 0.02825917381224309 0.03205913583313469 5.177370614388155e-07 6.2858907455797315 -0.06163366770987255 GLIVYCVT(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLIVYCVTSPK 11 0 E9PCH4;Q8TEU7;A0A5F9ZHG7;Q8TEU7-4 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 1 GLIVYCVT(0.5)S(0.5)PK 176.95 0.0055869 10502000.0 85937.0 67754.0 65055.0 109310.0 110450.0 93604.0 101940.0 112260.0 94598.0 85463.0 True False 100484.43676688119 74480.16934941342 66606.15792246143 103185.71508780147 88808.1153719592 88695.2414595755 92283.50521831225 109313.29394930175 95981.31678816685 100956.76537526432 0.9953214764099518 0.737743221789691 0.6597493261088649 1.0220782599784368 0.87966482525319 0.8785467831688965 0.9140893616716732 1.082773339091992 0.9507170364600793 1.0 16.62337806709037 -6.986136340405351 0.7477965870581768 1.013850097801199 0.8214129033827309 0.2616611603282408 0.10650435644687574 0.8960516860852719 1.0522308436836099 0.08408838111442896 0.06650306019763676 1.0324372362987294e-07 6.986136340405351 -0.19243719441846818 GLIVYCVT(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 1 GLIVYCVTSPK 11 0 E9PCH4;Q8TEU7;A0A5F9ZHG7;Q8TEU7-4 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 1 GLIVYCVT(0.674)S(0.326)PK 99.815 0.010772 7359700.0 116600.0 110130.0 103570.0 98588.0 105730.0 99352.0 88522.0 87753.0 96179.0 80860.0 True False 114937.26261817888 109875.00075136681 95054.87439176146 105838.49039992673 99511.1692731779 95102.94656082388 93105.2360185274 91830.3247380764 85346.30821023011 94836.54326082276 1.211951202207723 1.1585723917539335 1.0023021835616492 1.1160095756426511 1.0492914002516818 1.0028090785560209 0.9817443025360608 0.9683010533768766 0.8999306098231326 1.0 16.533155457897053 -2.0848619355919085 0.2987951926571403 0.946274675082276 2.6033631211916215 0.759725912195069 0.04439838805642456 18.636798481677328 0.36119118195454514 0.046830208636893945 15.484716422737932 0.00822504086589937 2.0848619355919085 1.6570884461093454 GLIVYCVTS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLIVYCVTSPK 11 0 E9PCH4;Q8TEU7;A0A5F9ZHG7;Q8TEU7-4 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 1 GLIVYCVT(0.074)S(0.926)PK 155.53 0.00065418 11485000.0 86795.0 65825.0 59555.0 102290.0 102910.0 99266.0 107140.0 116070.0 103400.0 74572.0 True False 101487.67922060909 72359.67097773025 60975.01706359523 96559.02292865435 82745.52424561631 94060.31621219419 96990.92357357276 113023.28548633085 104912.0293864185 88091.31328837272 1.1520736316914981 0.821416644577157 0.6921796802369093 1.0961242297814544 0.9393153667120773 1.067759268207088 1.1010271041829809 1.2830241855555231 1.1909463654263168 1.0 16.42671214110522 -6.8803427116664055 1.2940211298449675 1.1746240891551563 0.9111297331062712 0.32038654545867973 0.13849471775865782 0.4695026620852306 1.6347908711000056 0.0721088315471067 0.058361856384170394 1.3172168824827057e-07 6.8803427116664055 -0.26349435604888505 GLIVYCVTS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 GLIVYCVTSPK 11 0 E9PCH4;Q8TEU7;A0A5F9ZHG7;Q8TEU7-4 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 1 GLIVYCVT(0.162)S(0.838)PK 105.2 0.0025885 9027900.0 150830.0 113660.0 110420.0 126700.0 121830.0 101490.0 98802.0 88637.0 105440.0 88185.0 True False 148679.13654116553 113396.82725324936 101341.69383352618 136017.9406588099 114664.19892699562 97149.50928474533 103917.48411810104 92755.39860527706 93564.2368675767 103427.65975087367 1.4375181348905035 1.0963878282307502 0.9798316434658585 1.315102178531705 1.108641529772475 0.9392991151375703 1.0047359126988584 0.8968142451322703 0.9046345735071739 1.0 16.65826253290477 -6.649655734694175 3.8886078599215406 0.9456493473402531 1.1860860455629503 0.5095138198460542 0.11906244265170882 0.20678657837427347 5.840174165018902 0.04146630085029673 0.041092653769424656 2.240496476738289e-07 6.649655734694175 0.2404366982226972 GLLAQGLRPES(ph)PPPAGPLLNGAPAGES(ph)PQPK ddPTM_PC-9_AZD4547_30min_R2 1 GLLAQGLRPESPPPAGPLLNGAPAGESPQPK 31 1 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 2 GLLAQGLRPES(1)PPPAGPLLNGAPAGES(1)PQPK 82.54 8.3167e-07 2913600.0 5199.5 5002.5 5920.0 6698.5 6876.4 5589.5 4021.4 7160.5 6812.1 5946.7 True False 6852.832843681488 6619.460295780703 5841.496931940717 5154.264315793347 5921.73055530399 5239.987681395197 4379.296809515939 6054.0092569207545 7172.173698822217 5738.507843034607 1.1941837549284606 1.1535159447094587 1.0179470154477734 0.8981889468095067 1.0319286332407436 0.9131272143777737 0.7631420796664978 1.054979695509017 1.2498325165709745 1.0 12.486459933181221 -5.269664013471425 3.2022445594653326 0.9778113904578944 1.1847514379869322 0.27765574662711157 0.11850196315928391 0.3234585964625261 6.823342273187334 0.03367819131801767 0.094930123477207 5.374474250976298e-06 5.269664013471425 0.20694004752903772 GLLAQGLRPES(ph)PPPAGPLLNGAPAGES(ph)PQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GLLAQGLRPESPPPAGPLLNGAPAGESPQPK 31 1 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 2 GLLAQGLRPES(1)PPPAGPLLNGAPAGES(1)PQPK;GLLAQGLRPES(1)PPPAGPLLNGAPAGES(1)PQPK;GLLAQGLRPES(1)PPPAGPLLNGAPAGES(1)PQPK 62.1 0.0016267 7670700.0 18790.800000000003 15955.599999999999 15993.6 18869.800000000003 18908.7 18349.7 21224.8 22052.2 17714.4 17455.4 True False 21971.711304782733 17539.566521113138 16374.948080065762 17812.586282717017 15203.675972238694 17387.40942919932 19214.23328975511 21473.353116237275 17973.43958764771 20619.925843129622 1.065557241666973 0.8506124927193746 0.7941322488083414 0.8638530719377933 0.7373293234856334 0.8432333637607456 0.9318284379842774 1.0413884744106394 0.8716539392228854 1.0 14.331751523800499 -7.391396351131073 4.195576409456086 0.970276268680603 0.8507721884233073 0.2455268451459247 0.08851853550427446 0.3241504475938206 9.481165497698434 0.039663662725825964 0.025784946038035488 4.0607256510444815e-08 7.391396351131073 -0.11950408025729575 GLLAQGLRPES(ph)PPPAGPLLNGAPAGES(ph)PQPK ddPTM_PC-9_Lapatinib_30min_R1 1 GLLAQGLRPESPPPAGPLLNGAPAGESPQPK 31 1 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 2 GLLAQGLRPES(1)PPPAGPLLNGAPAGES(1)PQPK 69.28399999999999 0.00020978 2509300.0 13304.0 13663.0 12820.0 9630.6 12341.0 11523.0 9176.6 10603.0 12351.0 9395.8 True False 13114.282520345201 13631.364162952214 11765.98908663109 10338.86645073981 11615.126643339521 11030.188151424965 9651.719446551355 11095.654088154542 10959.900318204098 11019.851510883467 1.1900598213499722 1.236982562740483 1.0677084963450478 0.9382037898177575 1.0540184349914468 1.0009380017989615 0.8758484120243442 1.0068787294634787 0.9945597095732043 1.0 13.427817163716655 -5.439492993525097 3.433501711024663 0.9815798534149962 1.212717779372328 0.795753084448428 0.046476850076034956 0.10180288466438418 2.263648889512394 0.012959530716075673 0.029187163591171395 3.63502168880963e-06 5.439492993525097 0.23113792595733185 GLLAQGLRPES(ph)PPPAGPLLNGAPAGESPQPK ddPTM_PC-9_AZD4547_30min_R2 3 GLLAQGLRPESPPPAGPLLNGAPAGESPQPK 31 1 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 1 GLLAQGLRPES(0.996)PPPAGPLLNGAPAGES(0.004)PQPK;GLLAQGLRPES(0.998)PPPAGPLLNGAPAGES(0.002)PQPK;GLLAQGLRPES(0.995)PPPAGPLLNGAPAGES(0.005)PQPK 47.795 0.0063813 1509402000.0 246433.0 278178.0 351654.0 475577.0 362740.0 338515.0 277219.0 339532.0 326234.0 358300.0 True False 324793.5678751722 368093.5984327207 346990.8381933579 365940.0702414053 312379.81234817096 317347.60353654023 301890.9539556364 287065.1310691738 343478.06322008854 345756.0260580327 0.9393721103812602 1.0646050124689332 1.0035713394482326 1.058376550695272 0.9034688879023043 0.917836797104082 0.8731328775307192 0.8302534429898611 0.9934116467501225 1.0 18.399394870247228 -6.272672188915533 24.710776835353947 0.9087766971070612 1.0189965273436066 0.3955045230559081 0.05765441350104891 549.1746900971685 1208113.0586688467 0.017157222486352507 0.01963421121194915 5.337376155255308e-07 6.272672188915533 0.11021983023654536 GLLAQGLRPES(ph)PPPAGPLLNGAPAGESPQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GLLAQGLRPESPPPAGPLLNGAPAGESPQPK 31 1 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 1 GLLAQGLRPES(1)PPPAGPLLNGAPAGESPQPK;GLLAQGLRPES(1)PPPAGPLLNGAPAGESPQPK;GLLAQGLRPES(0.999)PPPAGPLLNGAPAGES(0.001)PQPK;GLLAQGLRPES(0.999)PPPAGPLLNGAPAGES(0.001)PQPK;GLLAQGLRPES(1)PPPAGPLLNGAPAGESPQPK 75.191 6.637100000000001e-07 1153925000.0 247747.0 251833.0 236705.0 271756.0 317046.0 300821.0 294297.0 268342.0 268655.0 231941.0 True False 289685.67387370515 276833.3159336837 242348.94490871136 256530.39236483982 254923.11223375474 285045.41719489545 266419.057634233 261298.30683185026 272583.57112967456 273990.0672560547 1.05728531247442 1.010377196173947 0.8845172649351063 0.9362762487484696 0.9304100502136775 1.0403494551811947 0.9723675763225886 0.9536780272682531 0.9948666163687396 1.0 18.06376406769497 -6.723059102646374 24.99999784328227 0.9881147445092298 0.9604316462432918 0.07438199539090862 0.04844806810580967 529.3741662013016 344820.4320968058 0.017274121710609044 0.017273808427128053 1.8920861092580142e-07 6.723059102646374 -0.027683098265937955 GLLAQGLRPES(ph)PPPAGPLLNGAPAGESPQPK ddPTM_PC-9_Lapatinib_30min_R1 3 GLLAQGLRPESPPPAGPLLNGAPAGESPQPK 31 1 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 1 GLLAQGLRPES(0.992)PPPAGPLLNGAPAGES(0.008)PQPK;GLLAQGLRPES(1)PPPAGPLLNGAPAGESPQPK;GLLAQGLRPES(0.999)PPPAGPLLNGAPAGES(0.001)PQPK 86.376 3.2128e-09 1199592600.0 243242.0 201292.0 202314.5 187677.0 261777.0 226125.0 209561.2 225325.0 230826.4 193927.0 True False 239773.32447488006 200825.92074134373 185680.9827665539 201479.3926521187 246379.79153338404 216454.1608731208 220411.25354517312 235794.42208935402 204828.30012224978 227447.02355851527 1.0541941623307003 0.8829569083794903 0.8163702468446846 0.8858299814166797 1.0832403417668728 0.9516684698115369 0.969066335082059 1.0367004078586732 0.9005538824716852 1.0 17.79517102964028 -6.210826712196936 24.997444715457842 0.9890563288259298 0.9012414611613049 0.2259629839497339 0.07215260948024939 521.5005309132722 257567.15852653788 0.02138197711787044 0.027603963122083058 6.154223833571278e-07 6.210826712196936 -0.08781486766462487 GLLASDLNTDGDMRVT(ph)PEPGAGPTQGLLR ddPTM_PC-9_AZD4547_30min_R2 3 GLLASDLNTDGDMRVTPEPGAGPTQGLLR 29 1 Q86YP4-2;Q86YP4;Q86YP4-3;C9JMI3;C9JGN4;C9JHD7;C9JJK9;V9GYX5;C9JVY3;V9GY85;H7C3H1 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 1 GLLAS(0.005)DLNT(0.006)DGDMRVT(0.968)PEPGAGPT(0.021)QGLLR;GLLAS(0.014)DLNT(0.019)DGDMRVT(0.955)PEPGAGPT(0.012)QGLLR;GLLAS(0.022)DLNT(0.03)DGDMRVT(0.94)PEPGAGPT(0.008)QGLLR 53.208999999999996 0.0034700000000000004 55899200.0 42354.0 43328.0 67615.0 84193.0 73439.0 63965.0 56617.0 75053.0 55848.0 55070.0 True False 55821.69098207246 57332.92867477989 66718.38092114375 64783.60461888328 63243.26249941382 59965.25843822235 61655.80331833784 63455.2833963652 58800.01126404829 53142.016062003444 1.0504247884939575 1.0788625069829247 1.2554732745423147 1.2190656173694465 1.190080226268133 1.1283963778916082 1.160208209760069 1.1940699299463677 1.1064693367192426 1.0 15.697565340300006 -8.587244169106416 4.337284410732838 1.0000449941769731 1.1617561222073072 0.4083649988376149 0.0585875156670916 0.3377696272685374 18.0717784297085 0.060885961131123705 0.01590155628065573 2.5867581786930605e-09 8.587244169106416 0.16171112803033405 GLLASDLNTDGDMRVT(ph)PEPGAGPTQGLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GLLASDLNTDGDMRVTPEPGAGPTQGLLR 29 1 Q86YP4-2;Q86YP4;Q86YP4-3;C9JMI3;C9JGN4;C9JHD7;C9JJK9;V9GYX5;C9JVY3;V9GY85;H7C3H1 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 1 GLLAS(0.014)DLNT(0.095)DGDMRVT(0.886)PEPGAGPT(0.005)QGLLR;GLLAS(0.025)DLNT(0.028)DGDMRVT(0.923)PEPGAGPT(0.024)QGLLR;GLLAS(0.005)DLNT(0.056)DGDMRVT(0.912)PEPGAGPT(0.027)QGLLR 45.332 0.017516 39670200.0 47818.0 45408.0 54942.0 63021.0 66461.0 60415.0 48764.0 63126.0 53992.0 43006.0 True False 55912.642951449736 49915.80614898256 56252.02564869531 59490.13768683871 53438.44414428049 57246.73104547088 44144.72089921309 61469.00938752572 54781.53085717129 50802.64736469129 1.100585222460473 0.9825434054776229 1.1072656360776865 1.171004677370128 1.0518830595710476 1.1268454306036486 0.868945285120996 1.209956814775124 1.0783203966501436 1.0 15.63261605844444 -10.267048243249032 15.734958372452846 0.9999999065963625 1.076779238169092 0.06085676288534658 0.09127705536147146 0.0 0.0 0.08576242976372091 0.020800444507378665 5.4069425702800674e-11 10.267048243249032 0.07677933157272943 GLLASDLNTDGDMRVT(ph)PEPGAGPTQGLLR ddPTM_PC-9_Lapatinib_30min_R1 2 GLLASDLNTDGDMRVTPEPGAGPTQGLLR 29 1 Q86YP4-2;Q86YP4;Q86YP4-3;C9JMI3;C9JGN4;C9JHD7;C9JJK9;V9GYX5;C9JVY3;V9GY85;H7C3H1 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 1 GLLAS(0.001)DLNT(0.002)DGDMRVT(0.995)PEPGAGPT(0.002)QGLLR;GLLAS(0.004)DLNT(0.009)DGDMRVT(0.98)PEPGAGPT(0.008)QGLLR 78.043 2.4353000000000002e-06 31162000.0 32589.8 28368.7 39171.1 30137.2 31055.3 31898.3 31068.7 29719.5 32752.9 23804.3 True False 32125.06347576265 28303.014018117734 35950.603362818634 32353.59022275204 29228.688311068945 30534.084067569125 32677.28526568338 31100.37646636883 29063.92349867274 27918.841537764045 1.1506588993783684 1.0137603302713705 1.2876824890527974 1.1588442944163493 1.046916229369086 1.0936730317505334 1.1704384374789651 1.1139565523985415 1.0410146660046697 1.0 14.768951459263313 -8.351580652677818 2.669584847426961 1.0022667009152588 1.130290040786209 0.28738088247185656 0.0704222419281083 0.35613236210344157 4.7780316421681714 0.06782114715783429 0.018731008745607694 4.4506080315738334e-09 8.351580652677818 0.12802333987095027 GLLDVTCK ddPTM_PC-9_Lapatinib_30min_R1 1 GLLDVTCK 8 0 E5RJR5;P63208;E7ERH2;F8W8N3;P63208-2 E5RJR5 SKP1 S-phase kinase-associated protein 1 0 119.29 0.015969 2411200.0 35312.0 29843.0 33600.0 38173.0 32739.0 43387.0 29625.0 29374.0 30811.0 30683.0 False True 34808.44440457229 29773.900367048438 30837.53769975076 40980.369761395006 30813.35638735051 41531.43915003687 31158.83754376171 30738.8232750591 27340.740725786305 35986.51566747242 0.9672635363260532 0.8273626889074049 0.8569192412152385 1.1387701476871916 0.8562472864023944 1.1540833664976466 0.8658475811239941 0.8541761463959509 0.7597495956103113 1.0 15.135168802106406 -7.482867164869723 24.992981445784523 0.8561798018598727 0.9625487135482308 0.13564169282800065 0.117678220368294 972.4743369105303 607451.3763625172 0.0487341471435305 0.0328504598534865 3.2895223019803564e-08 7.482867164869723 0.10636891168835805 GLLEFEHQR ddPTM_PC-9_AZD4547_30min_R2 3 GLLEFEHQR 9 0 F5H6X6;Q14697;Q14697-2;E9PKU7;E9PNH1 F5H6X6 GANAB Neutral alpha-glucosidase AB 0 ;; 168.26 0.00014768 15984200.0 118279.0 147597.0 169315.0 220273.0 179615.0 164119.0 149013.0 191031.0 160577.0 162217.0 False True 155889.2616439661 195304.8438333523 167069.77247154445 169492.46303392533 154678.5576305804 153856.61298558017 162274.86832356825 161511.54840567397 169064.77239555732 156537.83220501195 0.9958567807416904 1.2476526669768149 1.067280478579384 1.0827571881278333 0.988122522535022 0.9828717493933333 1.0366495181244284 1.0317732533445851 1.0800250010753905 1.0 17.256151845578813 -5.868210787243256 2.3069083069499157 1.0215898087493507 1.12262984655151 0.2540764284264353 0.06439969979291252 0.35663896732083566 3.8625361998266405 0.018828317928701082 0.032209138819946165 1.3545318232245025e-06 5.868210787243256 0.10104003780215942 GLLEFEHQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GLLEFEHQR 9 0 F5H6X6;Q14697;Q14697-2;E9PKU7;E9PNH1 F5H6X6 GANAB Neutral alpha-glucosidase AB 0 ;;; 172.25 0.00095436 18507600.0 161371.0 190759.0 172762.0 188673.0 208928.0 177326.0 198069.0 143282.0 161386.0 137340.0 False True 188687.9230774687 209696.29283768858 176881.30128353357 178102.2634961188 167990.05820219722 168026.71239541777 179306.4704246217 139520.99931982794 163745.9649376841 162238.65481715833 1.163026920373067 1.2925174526010133 1.0902537467589175 1.097779463820374 1.035450265484022 1.0356761931044272 1.1052019053455457 0.859973842097415 1.0092906966112638 1.0 17.307758070003004 -5.728224705523397 0.5689824295485968 0.9738360016233731 1.2786635334259004 0.5984359109065522 0.06814631284899485 1.0462149172879824 0.526800708255485 0.04424690437326287 0.18671004381443362 1.8697144930671354e-06 5.728224705523397 0.3048275318025273 GLLEFEHQR ddPTM_PC-9_Lapatinib_30min_R1 4 GLLEFEHQR 9 0 F5H6X6;Q14697;Q14697-2;E9PKU7;E9PNH1 F5H6X6 GANAB Neutral alpha-glucosidase AB 0 ;;; 191.17 0.00051036 23444400.0 187620.0 171831.0 164093.0 147576.0 158804.0 164296.0 151262.0 144638.0 175159.0 123167.0 False True 184944.50439470564 171433.13587676504 150601.90695729785 158429.2313391047 149463.46094067654 157269.44307268198 159093.60622934985 151358.40950697902 155430.74891395928 144456.25184028893 1.2802803758135757 1.1867477779106563 1.0425433654737462 1.0967281050200883 1.0346624603407515 1.088699457926953 1.101327247540965 1.0477802627353305 1.0759710772906097 1.0 17.140273117271867 -5.023206008578124 2.6798224514590707 1.0652156031977549 1.2820981079824432 0.8430952331552091 0.030895741239872664 0.10711623397719922 1.3868599417058471 0.007745173563008178 0.04062632036819028 9.479686855244622e-06 5.023206008578124 0.2168825047846883 GLLPGGTQVLDGTS(ph)GFSPAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLLPGGTQVLDGTSGFSPAPK 21 0 Q96S94;Q96S94-3 Q96S94 CCNL2 Cyclin-L2 1 GLLPGGT(0.003)QVLDGT(0.206)S(0.562)GFS(0.228)PAPK 70.615 0.0026780999999999997 17217000.0 42001.0 40902.0 45295.0 53134.0 56214.0 49821.0 61203.0 52321.0 49463.0 41830.0 True False 49110.93974243675 44962.48024809912 46375.00458224411 50157.074242752235 45199.270235575445 47208.299055142044 55405.408768651876 50947.62918868188 50186.30280019753 49413.44787390221 0.993878020164927 0.9099239616478195 0.9385097898974409 1.0150490686411455 0.9147159767300413 0.9553735083536882 1.1212617445769117 1.0310478499434959 1.0156405788211251 1.0 15.592616104370196 -7.150458598641951 10.5092111232033 1.0445246954112173 0.9525357385739432 0.5047572429637445 0.04236605554475236 0.36205987434373565 32.055078439169 0.01591422834938564 0.012326756146111418 7.071986148178915e-08 7.150458598641951 -0.09198895683727404 GLLPGGTQVLDGTSGFS(ph)PAPK ddPTM_PC-9_AZD4547_30min_R2 2 GLLPGGTQVLDGTSGFSPAPK 21 0 Q96S94;Q96S94-3 Q96S94 CCNL2 Cyclin-L2 1 GLLPGGTQVLDGT(0.133)S(0.225)GFS(0.642)PAPK;GLLPGGTQVLDGTSGFS(1)PAPK 178.56 9.7577e-13 57155000.0 186309.0 164368.0 236513.0 285303.0 261645.0 246169.0 222441.0 255198.0 221169.0 239082.0 True False 245551.38653206168 217496.74160857222 233376.68308515128 219530.80123741002 225320.10807144846 230776.0135148714 242237.81807468348 215763.01296664553 232859.54181453778 230711.8119508968 1.0643208271639044 0.9427204431772345 1.0115506488884134 0.9515368952333204 0.9766301350856025 1.0002782760164366 1.0499584569438507 0.9352057492945663 1.0093091456630667 1.0 17.81573234324636 -7.790162363855084 24.99999202173202 0.9791931993916019 0.995142534599784 0.03151165305056802 0.040438913454610176 983.6093634728334 856103.3358757382 0.02120210090839789 0.010188131326076412 1.6212038862875427e-08 7.790162363855084 0.01594933520818209 GLLPGGTQVLDGTSGFS(ph)PAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLLPGGTQVLDGTSGFSPAPK 21 0 Q96S94;Q96S94-3 Q96S94 CCNL2 Cyclin-L2 1 GLLPGGTQVLDGT(0.052)S(0.161)GFS(0.788)PAPK 114.53 3.6841000000000004e-06 19759000.0 104190.0 105550.0 115110.0 128050.0 145670.0 122190.0 128590.0 118380.0 114450.0 91715.0 True False 121827.3091536983 116028.3064443513 117854.65895710594 120875.7736437013 117127.00920084454 115782.14129679854 116409.02428902079 115272.65043397788 116123.61473187235 108342.20348445962 1.1244677072787517 1.070942834026762 1.0878000923620754 1.115685021682612 1.0810838752937584 1.0686707263933957 1.0744568648700066 1.0639681188551084 1.0718225308065557 1.0 16.72523581246452 -14.522878745280051 0.12567306946973736 0.7143144917974784 1.1216631868549702 0.7748304344563477 0.015087118923504598 69.90188318785195 0.5588409636458305 5.004495907962724 0.12773754210777183 3.0000000000019767e-15 14.522878745280051 0.4073486950574918 GLLPGGTQVLDGTSGFS(ph)PAPK ddPTM_PC-9_Lapatinib_30min_R1 3 GLLPGGTQVLDGTSGFSPAPK 21 0 Q96S94;Q96S94-3 Q96S94 CCNL2 Cyclin-L2 1 GLLPGGTQVLDGT(0.001)S(0.009)GFS(0.99)PAPK;GLLPGGTQVLDGT(0.013)S(0.182)GFS(0.805)PAPK;GLLPGGTQVLDGT(0.001)S(0.008)GFS(0.991)PAPK 155.54 2.3794e-06 43240500.0 231064.0 198657.0 218710.0 198620.0 197650.0 190196.0 163330.0 180804.0 205062.0 147774.0 True False 227768.98498805214 198197.02192194958 200728.508045015 213227.1773768968 186024.61559485123 182061.7604485309 171786.4282201721 189204.81389745304 181965.75816140944 173316.53900352187 1.314179167767848 1.1435551567177447 1.158161299545314 1.230275994448308 1.0733229307739125 1.0504580895469608 0.9911715823997692 1.0916720065221721 1.049904176529349 1.0 17.403049806949042 -6.369335826817045 3.9983001229388857 1.0413529792447416 1.2028717082279743 0.7266689763967361 0.05086554197612903 0.13442214383732293 3.7677935783675007 0.01619810520155308 0.01855671126869012 4.272323924712583e-07 6.369335826817045 0.16151872898323272 GLLPGLLPAPADKLT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLLPGLLPAPADKLTPK 17 1 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 GLLPGLLPAPADKLT(1)PK;GLLPGLLPAPADKLT(1)PK 97.081 0.0010733 7269700.0 75919.0 66171.9 54878.2 74456.6 68642.0 54445.3 66168.1 51167.1 49002.3 42152.8 True False 88770.58723140045 72741.00891714786 56186.70441473248 70285.03809355418 55192.09285071998 51590.09262252711 59900.178552440775 49824.017841023764 49718.86593425632 49794.768958618835 1.7827291719170715 1.4608162752516864 1.128365601242684 1.41149441122949 1.1083913833717454 1.0360544631786575 1.2029411885055614 1.0005873886558092 0.9984756827684933 1.0 15.603706571765525 -1.5228787452803403 0.4367285559092229 1.034023388735294 16.292905795959854 0.8286540185028447 0.1023552921282877 33.065851020125756 0.4099049089339505 0.06677307481739331 446.0063084495878 0.02999999999999981 1.5228787452803403 15.25888240722456 GLLS(ph)PPMGQSGLR ddPTM_PC-9_Lapatinib_30min_R1 2 GLLSPPMGQSGLR 13 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 GLLS(0.692)PPMGQS(0.308)GLR;GLLS(0.768)PPMGQS(0.232)GLR 90.476 0.0055915 14207600.0 50295.0 46667.0 53592.0 39453.0 51096.0 43015.0 34412.0 33676.0 48595.0 39179.0 True False 49577.78407702662 46558.94542871192 49185.87263110244 42354.50523134983 48090.63373860113 41175.34872286253 36193.68498079084 35240.70990028221 43121.719371964115 45951.037947264005 1.078926315743398 1.013229461370287 1.0703974236131708 0.9217311974532162 1.0465625127726743 0.89607004677713 0.7876576155326185 0.7669186916022752 0.9384275371854064 1.0 15.48780982919125 -6.871156780354404 4.4759849024355916 0.8524039276375956 1.0219471835853597 0.48164886343020497 0.07572161990571251 0.17032687209790442 5.89370030996585 0.02673708275610921 0.023593810926428732 1.345374586010661e-07 6.871156780354404 0.1695432559477641 GLLS(ph)QGSPLSWEETKR ddPTM_PC-9_AZD4547_30min_R2 2 GLLSQGSPLSWEETKR 16 1 A0A0C4DGB2;E1CEI4;P48506;D6RGF8 A0A0C4DGB2 GCLC Glutamate--cysteine ligase catalytic subunit 1 GLLS(0.768)QGS(0.232)PLSWEETKR;GLLS(0.902)QGS(0.098)PLSWEETKR 85.20299999999999 0.002194 14084400.0 33032.0 36025.0 44342.0 59679.0 52495.0 45316.0 46040.0 53923.0 40894.0 46013.0 True False 43535.48889171782 47669.37674272861 43753.99610745187 45920.92858135871 45206.97537965834 42482.383356311766 50137.47080870191 45590.43937726941 43055.573353244356 44402.0988752672 0.9804826797493553 1.0735838609035067 0.9854037808069399 1.0342062592662153 1.0181269922994445 0.9567652077810954 1.1291689374762737 1.0267631605735679 0.969674282159376 1.0 15.438340253543098 GLLS(ph)QGSPLSWEETKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLLSQGSPLSWEETKR 16 1 A0A0C4DGB2;E1CEI4;P48506;D6RGF8 A0A0C4DGB2 GCLC Glutamate--cysteine ligase catalytic subunit 1 GLLS(0.955)QGS(0.045)PLSWEETKR 58.023999999999994 0.0253 4011400.0 24197.0 13018.0 17168.0 23469.0 27733.0 23584.0 20880.0 24405.0 19449.0 19562.0 True False 28293.074187465576 14310.3410070352 17577.350230002572 22154.10801752461 22298.917733006274 22347.213522740807 18902.09524189093 23764.394609234947 19733.40483110693 23108.435747293195 1.2243612893953535 0.6192691345934759 0.7606464765604697 0.9587021925583876 0.964968722974607 0.9670586865819529 0.8179738104559944 1.028386121376415 0.853948101329983 1.0 14.496131983967606 -5.789274229645217 24.65829879317187 0.9396458718637672 0.8432098877751463 0.038266396941341485 0.15416358197867444 485.9951523882161 430530.69462904707 0.04194738312846268 0.06223441186184353 1.6245226479647567e-06 5.789274229645217 -0.09643598408862097 GLLS(ph)QGSPLSWEETKR ddPTM_PC-9_Lapatinib_30min_R1 1 GLLSQGSPLSWEETKR 16 1 A0A0C4DGB2;E1CEI4;P48506;D6RGF8 A0A0C4DGB2 GCLC Glutamate--cysteine ligase catalytic subunit 1 GLLS(0.911)QGS(0.081)PLS(0.004)WEET(0.004)KR 51.166000000000004 0.041027999999999995 4287500.0 23029.0 16533.0 18530.0 15803.0 20774.0 14753.0 14356.0 13413.0 16496.0 12567.0 True False 22700.602236998624 16494.718854284496 17006.53492786849 16965.205337262607 19552.114163255435 14122.048580922708 15099.283435552525 14036.216946563878 14638.046769419076 14739.18920552508 1.5401527126396586 1.1191062564080083 1.1538311022897707 1.151027040951689 1.3265393293089827 0.958129269120785 1.024431074532408 0.952305907118847 0.9931378561808482 1.0 13.847369544325673 -6.769959105474234 24.993569442757256 0.9850467864180665 1.2386629881838576 0.5830556605777107 0.11464091051845025 146.01943309007214 428361.7130123233 0.039812189929981576 0.0356607943813977 1.698403571920915e-07 6.769959105474234 0.253616201765791 GLLSDS(ph)MTDVPVDTGVAAR ddPTM_PC-9_AZD4547_30min_R2 4 GLLSDSMTDVPVDTGVAAR 19 0 A0A087WYR3;O43399;O43399-5;O43399-7;O43399-2;O43399-4;O43399-3;A0A087WZ51 A0A087WYR3 TPD52L2 Tumor protein D54 1 GLLS(0.001)DS(0.995)MT(0.003)DVPVDTGVAAR;GLLS(0.028)DS(0.89)MT(0.082)DVPVDTGVAAR;GLLS(0.012)DS(0.494)MT(0.494)DVPVDTGVAAR;GLLS(0.003)DS(0.936)MT(0.06)DVPVDTGVAAR 201.04 2.1215e-15 50680000.0 110977.2 129845.8 224338.9 285222.0 220793.7 228495.8 197004.8 308494.8 249348.2 243700.4 True False 146265.64113084142 171815.91557698796 221364.01960556663 219468.4745359725 190140.3059316822 214207.92150470355 214537.8455511332 260824.0171652698 262528.2367975607 235168.52317262822 0.6219609629621793 0.7306076223936843 0.9412995269059532 0.9332391579245028 0.8085278734012692 0.9108698673396086 0.9122727933859124 1.10909408132741 1.116340882937164 1.0 17.84333544574318 -3.7798024005471325 0.3110051493276753 1.0599294873737177 5.594475182059514e-13 0.7059529763102625 0.07992795771044942 8.863276988115 0.4278120554260894 0.0932064187948459 3.9910666509977504 0.00016603421739514815 3.7798024005471325 -1.0599294873731582 GLLSDS(ph)MTDVPVDTGVAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 GLLSDSMTDVPVDTGVAAR 19 0 A0A087WYR3;O43399;O43399-5;O43399-7;O43399-2;O43399-4;O43399-3;A0A087WZ51 A0A087WYR3 TPD52L2 Tumor protein D54 1 GLLS(0.005)DS(0.989)MT(0.005)DVPVDTGVAAR;GLLS(0.174)DS(0.803)MT(0.022)DVPVDT(0.001)GVAAR;GLLS(0.001)DS(0.604)MT(0.395)DVPVDTGVAAR;GLLS(0.012)DS(0.962)MT(0.026)DVPVDTGVAAR;GLLS(0.002)DS(0.759)MT(0.239)DVPVDTGVAAR;GLLS(0.037)DS(0.941)MT(0.022)DVPVDTGVAAR 158.14 1.0453e-05 49921500.0 161799.3 189981.0 240654.0 241289.0 284307.0 194438.3 193182.8 188183.0 183556.0 157086.2 True False 189188.72580815828 208841.05813931156 246392.10404537705 227770.35959949237 228599.08426487658 184241.61325893516 174883.12666164569 183243.3956463698 186240.1592461647 185564.68456632522 1.0195298003513042 1.125435363023867 1.3277963132974835 1.2274445438355046 1.2319105049493932 0.9928700263712239 0.9424375498514552 0.987490675149852 1.0036401036189515 1.0 17.501562646923325 -6.770145922308256 23.949109772934584 0.9818276069230512 1.1931680998425296 0.6346786392423247 0.0761906785421393 76.8427265946811 211369.6278329182 0.028842455335666504 0.025853882278395766 1.6976731409388898e-07 6.770145922308256 0.21134049291947843 GLLSDS(ph)MTDVPVDTGVAAR ddPTM_PC-9_Lapatinib_30min_R1 6 GLLSDSMTDVPVDTGVAAR 19 0 A0A087WYR3;O43399;O43399-5;O43399-7;O43399-2;O43399-4;O43399-3;A0A087WZ51 A0A087WYR3 TPD52L2 Tumor protein D54 1 GLLS(0.002)DS(0.519)MT(0.478)DVPVDTGVAAR;GLLS(0.051)DS(0.949)MTDVPVDTGVAAR;GLLS(0.004)DS(0.857)MT(0.139)DVPVDTGVAAR;GLLS(0.001)DS(0.887)MT(0.112)DVPVDTGVAAR;GLLS(0.361)DS(0.638)MT(0.002)DVPVDTGVAAR;GLLS(0.012)DS(0.681)MT(0.307)DVPVDTGVAAR 201.75 1.3532e-15 47545000.0 159792.1 201039.4 225345.19999999998 180811.3 188333.5 174659.8 147951.5 141386.69999999998 167099.69999999998 141117.30000000002 True False 157513.43535171764 200573.90562112367 206818.1875136276 194108.76617081478 177256.09380790716 167190.00750588 155611.7047377507 147956.04223952457 148279.1721481506 165509.2372780175 0.9516896938334096 1.2118592830211983 1.2495869772284707 1.172797176539196 1.0709740237045358 1.0101551445436197 0.9401995157307067 0.893944317989892 0.8958966555992016 1.0 17.33655221233513 -6.797350417016687 1.6908252267272217 0.9231034924901012 1.1568905135753242 0.5903391190355961 0.07953181479547974 0.24455842182700485 1.446452173737065 0.03526206427603189 0.031257143701078766 1.5945920075540763e-07 6.797350417016687 0.2337870210852231 GLLSDSMT(ph)DVPVDTGVAAR ddPTM_PC-9_AZD4547_30min_R2 1 GLLSDSMTDVPVDTGVAAR 19 0 A0A087WYR3;O43399;O43399-5;O43399-7;O43399-2;O43399-4;O43399-3;A0A087WZ51 A0A087WYR3 TPD52L2 Tumor protein D54 1 GLLS(0.001)DS(0.333)MT(0.666)DVPVDTGVAAR 168.16 2.548e-07 14585000.0 12753.0 19247.0 25464.0 29116.0 29116.0 21439.0 22431.0 32120.0 26059.0 30777.0 True False 16808.18872112127 25468.216354401062 25126.330722117982 22403.75603771579 25073.745978743373 20098.415940859046 24427.315545395122 27156.59204417215 27436.425539497108 29699.506597789717 0.5659416820874782 0.8575299482011073 0.8460184562119265 0.7543477520055202 0.8442478967179003 0.6767255837965604 0.8224822006710725 0.9143785589418911 0.9238007186805914 1.0 14.858151343072636 -7.75861916204547 2.508137812615145 0.9529644019948855 0.7685093409055725 0.49398163862028865 0.08540400637681116 0.26487343125170315 3.3324578226021804 0.05408656013006563 0.023832706958068037 1.7433349542850552e-08 7.75861916204547 -0.18445506108931298 GLLSGQT(ph)SPTNAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLLSGQTSPTNAK 13 0 G3V1P3;Q969J3 G3V1P3 LOH12CR1 Loss of heterozygosity 12 chromosomal region 1 protein 1 GLLSGQT(0.772)S(0.226)PT(0.002)NAK 157.33 0.00054985 7528300.0 32123.0 39649.0 39003.0 36606.0 43228.0 46128.0 50986.0 38129.0 37256.0 29922.0 True False 37560.789441829846 43585.090688887605 39932.979439701194 34555.08449825324 34757.78371479448 43708.96647629694 46156.23697332618 37128.15415101492 37800.79851857267 35346.62173757831 1.062641565032439 1.2330765585597865 1.1297537777774942 0.9776064245912488 0.9833410381576067 1.2365811590369982 1.305817492715457 1.050401773234883 1.0694317210627582 1.0 15.109284715225067 -7.958002354054166 24.999982605731883 1.0431140600337292 1.1322511466393927 0.14732536526129325 0.1023074651942685 311.0399511929069 185152.72744975227 0.0614755109805502 0.02953183165995944 1.1015333387628743e-08 7.958002354054166 0.08913708660566355 GLLSGQT(ph)SPTNAK ddPTM_PC-9_Lapatinib_30min_R1 1 GLLSGQTSPTNAK 13 0 G3V1P3;Q969J3 G3V1P3 LOH12CR1 Loss of heterozygosity 12 chromosomal region 1 protein 1 GLLS(0.007)GQT(0.344)S(0.344)PT(0.305)NAK 100.19 0.0056672 8086600.0 61270.0 55757.0 60258.0 52359.0 61355.0 59799.0 53590.0 48512.0 62040.0 45787.0 True False 60396.27856445811 55627.89809219988 55303.81984260661 56209.65552450374 57746.21952857112 57241.536168277446 56364.62798211616 50766.04462176303 55052.401889837485 53701.22194265748 1.1246723329489532 1.0358776966304364 1.0298428572381535 1.0467109218580684 1.0753241255894124 1.06592613906254 1.0495967492565192 0.9453424481843513 1.025161065210449 1.0 15.712667295889657 -7.628803951426843 7.502470596233703 0.9892918889657422 1.059909051294007 0.5296240182689667 0.030768652251368173 0.17949846172739065 11.40762442139293 0.014284389860275599 0.008190987352876442 2.3506937280622336e-08 7.628803951426843 0.07061716232826487 GLLSGQTS(ph)PTNAK ddPTM_PC-9_AZD4547_30min_R2 1 GLLSGQTSPTNAK 13 0 G3V1P3;Q969J3 G3V1P3 LOH12CR1 Loss of heterozygosity 12 chromosomal region 1 protein 1 GLLS(0.01)GQT(0.235)S(0.742)PT(0.013)NAK 69.21600000000001 0.031027 2667900.0 29820.0 22124.0 37638.0 43530.0 43657.0 35897.0 28206.0 43817.0 34896.0 41971.0 True False 39302.1397054682 29275.15034159969 37138.895527767665 33494.831031795824 37595.979124673664 33652.354915295364 30716.279357737723 37046.08946449223 36740.531318404035 40501.60806497815 0.9703846731817265 0.722814518737936 0.9169733574080424 0.827000028691673 0.9282589240495616 0.830889352869785 0.7583965384401162 0.9146819406542548 0.9071375946224138 1.0 15.305691569060626 -8.500579430577064 1.6692388618051082 0.9966964663394117 0.8510750922981307 0.263964588829094 0.07323339308163132 0.47823925459690586 2.964620083339502 0.06580417951431877 0.019038713206694324 3.1580613998678763e-09 8.500579430577064 -0.14562137404128095 GLLSGQTS(ph)PTNAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLLSGQTSPTNAK 13 0 G3V1P3;Q969J3 G3V1P3 LOH12CR1 Loss of heterozygosity 12 chromosomal region 1 protein 1 GLLS(0.004)GQT(0.223)S(0.74)PT(0.033)NAK 63.966 0.043351 4668100.0 22688.0 23043.0 31851.0 28283.0 32383.0 32252.0 32756.0 27443.0 28830.0 25274.0 True False 26528.630291574118 25330.55675411832 32610.44863559017 26698.39520472318 26037.783613310574 30560.648343598892 29653.11454709672 26722.650328262025 29251.58420899855 29855.976131126066 0.8885534398561146 0.8484250068685641 1.092258665145182 0.8942395682346832 0.872112956513424 1.0236023839708988 0.9932053273643311 0.8950519725396812 0.9797564172923686 1.0 14.865732117464841 -6.76172575831303 24.99999998985575 0.97269409271968 0.9234273478196751 0.14886432295434127 0.06976160203272058 19.82272014924954 1730346.3385200032 0.024709521464004482 0.023162752082911183 1.7309090223443697e-07 6.76172575831303 -0.04926674490000493 GLLSGQTS(ph)PTNAK ddPTM_PC-9_Lapatinib_30min_R1 1 GLLSGQTSPTNAK 13 0 G3V1P3;Q969J3 G3V1P3 LOH12CR1 Loss of heterozygosity 12 chromosomal region 1 protein 1 GLLS(0.102)GQT(0.291)S(0.598)PT(0.009)NAK 102.97 0.0016157 4183500.0 44341.0 40690.0 47097.0 38467.0 39534.0 45131.0 41225.0 41627.0 45375.0 36380.0 True False 43708.68920885651 40595.78480498614 43224.86645967745 41295.99150215028 37208.68784683453 43200.85233549942 43359.4287845258 43561.1423868348 40264.389680067296 42668.234526697095 1.024384760553156 0.9514287444817 1.0130455815469017 0.9678392359147596 0.8720465765592766 1.0124827711929132 1.0161992701478246 1.020926758982236 0.9436619566453883 1.0 15.380874797276842 GLLSGQTSPT(ph)NAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLLSGQTSPTNAK 13 0 G3V1P3;Q969J3 G3V1P3 LOH12CR1 Loss of heterozygosity 12 chromosomal region 1 protein 1 GLLSGQT(0.011)S(0.011)PT(0.978)NAK 82.645 0.025138999999999998 5286400.0 26852.0 28347.0 30927.0 31150.0 41099.0 26989.0 39991.0 27943.0 31877.0 32712.0 True False 31397.513248825282 31161.10282120349 31664.416971300634 29404.766489662572 33045.9459816401 25573.649328580872 36202.762970232754 27209.525858055807 32343.140819640867 38642.4266519505 0.8125140155306595 0.806396117455802 0.8194210279933947 0.7609451330401463 0.8551726391119923 0.6618023645078207 0.9368656708935073 0.7041360549928711 0.8369852419195398 1.0 15.237898074365164 -8.548903526625322 22.795763345707172 1.0000000022873285 0.7954213537625017 0.4213335626400857 0.07207007012255584 2148.2670464868943 1881719.3498229836 0.06282475761983328 0.016221282723261406 2.825507558242268e-09 8.548903526625322 -0.20457864852482688 GLLSNHT(ph)GSPR ddPTM_PC-9_Lapatinib_30min_R1 1 GLLSNHTGSPR 11 0 Q13111 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 GLLSNHT(0.67)GS(0.33)PR 91.307 0.017329 3845200.0 24668.0 17746.0 49483.0 17904.0 34547.0 47207.0 29736.0 25986.0 54330.0 21215.0 True False 24316.22979644284 17704.910227311 45414.69874990376 19220.719885993134 32515.01338201526 45188.0666548918 31275.58458063457 27193.404426556997 48210.78327973676 24881.984482789416 0.9772624773261995 0.7115553921978082 1.8252040459761794 0.7724753585988242 1.3067692974612022 1.8160957654381575 1.2569570004461474 1.0928953213264145 1.9375779015168024 1.0 14.602813932916092 -5.235998175909282 24.937368443902745 1.366754215880555 0.8444088432224128 0.2503893571558543 0.36763465900911785 1026.0178565371712 1005695.0795071424 0.09004607982146302 0.2380481173103028 5.807668568090583e-06 5.235998175909282 -0.5223453726581422 GLLSNHTGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 GLLSNHTGSPR 11 0 Q13111 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 GLLSNHT(0.426)GS(0.574)PR;GLLSNHT(0.07)GS(0.93)PR 113.54 0.0008788 12663400.0 19628.4 19329.800000000003 92675.0 184723.0 126573.0 104126.0 43930.0 149723.0 71832.0 105786.0 True False 25869.82290391724 25577.77983515879 91446.06894723071 142137.96629190046 109000.52375901515 97614.98475945205 47839.68489631348 126586.75064226623 75628.89287206547 102082.46433875221 0.25342083061465265 0.2505599762000361 0.8958058520587288 1.3923837675021968 1.0677693222344822 0.9562365621927466 0.46863763728862823 1.2400440316781398 0.7408607674389329 1.0 16.639375536692818 -5.2849534633160875 4.957616466898722 0.9828158339960104 0.2435834584814345 0.5937366532673746 0.23820894782594948 0.1188805128892139 8.386334234716028 0.06433901083479204 0.15029953996108883 5.188556337569128e-06 5.2849534633160875 -0.7392323755145759 GLLSNHTGS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLLSNHTGSPR 11 0 Q13111 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 GLLSNHT(0.235)GS(0.765)PR;GLLSNHT(0.07)GS(0.93)PR 113.54 0.0008788 5363800.0 20562.5 26185.0 71026.0 47318.0 67457.0 57966.0 49560.0 38746.0 50451.0 30279.0 True False 24043.32512211269 28784.473749363708 72719.52920760504 44666.92586702584 54239.2850941263 54926.160916688976 44865.31801667215 37728.95855478045 51188.750431085144 35768.343011567886 0.672195665153871 0.8047471961464495 2.033069554943787 1.248783759778306 1.516404745855426 1.5356082024522422 1.254330344633583 1.0548142680967492 1.4311188643692587 1.0 15.126395665778471 -5.0318178480835725 24.17326685117505 1.3890050243067456 0.7053331469114752 0.4715470422380349 0.2749948384230625 300.19376926759895 228069.94047960005 0.06838219693726123 0.18138019974790992 9.29356095849121e-06 5.0318178480835725 -0.6836718773952704 GLLSNHTGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 GLLSNHTGSPR 11 0 Q13111 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 GLLSNHT(0.21)GS(0.79)PR 75.02 0.012576 3879700.0 21658.0 15361.0 44614.0 18704.0 28557.0 37953.0 22947.0 20226.0 42055.0 16536.0 True False 21349.15294840922 15325.432548277022 40946.009135020264 20079.554554714905 26877.33340522215 36329.83866276419 24135.083379466694 21165.773798643186 37318.3230412172 19394.22556716501 1.1007994557180958 0.7902059556440051 2.1112474428648005 1.035336754498214 1.3858420544889538 1.873229665033476 1.2444468739359253 1.0913441078295727 1.9241976387238793 1.0 14.24333954816344 -5.168574737692927 24.999831724418396 1.4511115864977562 0.9454987662929341 0.2260243934219941 0.3793139347800414 83.78923298494105 22552.35212245017 0.09142956750827594 0.24189992256700701 6.783053809501386e-06 5.168574737692927 -0.5056128202048221 GLLSQGS(ph)PLSWEETKR ddPTM_PC-9_Lapatinib_30min_R1 1 GLLSQGSPLSWEETKR 16 1 A0A0C4DGB2;E1CEI4;P48506;D6RGF8 A0A0C4DGB2 GCLC Glutamate--cysteine ligase catalytic subunit 1 GLLS(0.159)QGS(0.832)PLS(0.009)WEETKR 55.724 0.029539 13476000.0 43926.0 28647.0 48624.0 45542.0 50230.0 40193.0 36819.0 30709.0 41626.0 35442.0 True False 43299.607184958135 28580.669631566445 44626.32241406791 48891.31060365837 47275.570155979614 38474.03908445918 38725.307663249405 32135.852248716183 36937.64153878747 41568.10247650354 1.0416546487642377 0.6875625282082994 1.07357131443017 1.1761737411827804 1.1373040225423383 0.9255664028976718 0.9316111478780867 0.7730892278973052 0.888605429118795 1.0 15.34318927208186 -6.984807823229102 24.405065613294454 0.886441701858324 1.0174488716734367 0.1649895695559368 0.1341300563711786 349.6760257891131 561724.6023279547 0.0514383364082123 0.04534666187633052 1.0356003219344902e-07 6.984807823229102 0.13100716981511262 GLLTDS(ph)PAATVLAEAR ddPTM_PC-9_AZD4547_30min_R2 2 GLLTDSPAATVLAEAR 16 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 GLLT(0.445)DS(0.52)PAAT(0.034)VLAEAR;GLLT(0.001)DS(0.656)PAAT(0.342)VLAEAR 99.915 0.0018479 5672400.0 16090.800000000001 14192.7 19337.3 25208.0 22327.0 20051.9 15177.7 21528.4 16428.9 16530.1 True False 21207.33969056834 18780.21272162455 19080.87476723263 19396.685059717656 19227.28144207319 18798.05152313595 16528.48589689909 18201.680453417037 17297.298113735902 15951.386230370856 1.3294982256896484 1.1773404800309901 1.1961891268674407 1.2159874245153113 1.2053674310427736 1.1784588029938832 1.0361786529517703 1.141072016597636 1.0843758569899387 1.0 13.961394184152736 -1.5228788882497246 0.0942041816337091 0.8844679534506641 2.0058331077772835 0.752924723207081 0.04521839031576675 74.04209988586982 0.5004664820276868 0.7352810962075509 10.720790620885039 0.029999990124026245 1.5228788882497246 1.1213651543266194 GLLYDS(ph)DEEDEERPAR ddPTM_PC-9_AZD4547_30min_R2 15 GLLYDSDEEDEERPAR 16 1 P49736 P49736 MCM2 DNA replication licensing factor MCM2 1 GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLY(0.001)DS(0.999)DEEDEERPAR 238.64 1.4802000000000001e-36 694038150.0 583097.41 582022.7 732050.5999999999 931895.8 850035.9999999999 789404.6 635698.4 821619.6 654775.1900000001 716095.6 True False 768510.2572004246 770150.1557007664 722343.1307306349 717061.6209565859 732023.1740894051 740043.0055705719 692274.3260890192 694657.1697601463 689385.2697933556 691025.3110065353 1.1121304024030987 1.1145035405128347 1.045320799723649 1.037677794916262 1.0593290324245186 1.070934731019676 1.0018074809454731 1.0052557535820517 0.9976266553669491 1.0 19.398379029326527 -1.5228787452824588 0.21674487733750364 0.9871718961311016 1.6974983668076342 0.7725273152867617 0.0202238623788754 25.392329943961656 0.32193386726809387 0.03542584800650854 6.278905610915095 0.02999999999985347 1.5228787452824588 0.7103264706765327 GLLYDS(ph)DEEDEERPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 9 GLLYDSDEEDEERPAR 16 1 P49736 P49736 MCM2 DNA replication licensing factor MCM2 1 GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR 204.17 3.4833e-16 257465100.0 427672.10000000003 435294.5 537313.7 511629.10000000003 547370.0 503758.80000000005 523079.5 476990.1 468804.5 365199.9 True False 500068.5396209931 478507.66119887074 550125.2963815544 482964.1802509226 440116.7778284225 477340.80171131645 473529.62299237103 464469.615287786 475659.8789215218 431407.75094918255 1.1591552041444393 1.1091772462271692 1.2751863988794123 1.1195074246772472 1.0201874603784433 1.1064724745002195 1.097638190205234 1.0766371588499761 1.1025761078121008 1.0 18.718692571555238 -1.5228794613239995 0.07037332968914152 0.8826335986880809 1.6401440128003992 0.4011706703327226 0.055361588339983926 271.74512928661 1.4169963843585842 2.652533857511336 20.381894766216952 0.029999950537496916 1.5228794613239995 0.7575104141123183 GLLYDS(ph)DEEDEERPAR ddPTM_PC-9_Lapatinib_30min_R1 15 GLLYDSDEEDEERPAR 16 1 P49736 P49736 MCM2 DNA replication licensing factor MCM2 1 GLLYDS(1)DEEDEERPAR;GLLY(0.003)DS(0.997)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLY(0.003)DS(0.997)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLY(0.001)DS(0.999)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR 257.81 7.272599999999998e-78 1006606350.0 795388.5000000001 770171.4 855498.5000000001 742734.9999999999 825327.1 809707.8 727351.7000000001 763125.8999999999 865739.0 695096.1 True False 784046.1141336121 768388.1154424886 785162.7156497104 797358.2095913267 776782.9826335101 775078.4849150709 765010.4120667984 798583.5152420643 768230.3571841717 815242.5347276654 0.9617335709740973 0.9425270182929935 0.9631032265901052 0.9780625711067529 0.9528244044491585 0.950733618399816 0.938383829938845 0.9795655663487111 0.9423335074645016 1.0 19.636869799541877 -11.121632595608936 5.2770235988429395 1.0003292798474674 0.9568530051712154 0.47967302353316144 0.013562551302932737 5.210416008971965e-05 3.9618309273304114e-06 0.013022732182115146 0.0031346000463492495 7.557312907721748e-12 11.121632595608936 -0.043476274676252036 GLLYDS(ph)DEEDEERPARK ddPTM_PC-9_Lapatinib_30min_R1 2 GLLYDSDEEDEERPARK 17 2 P49736 P49736 MCM2 DNA replication licensing factor MCM2 1 GLLYDS(1)DEEDEERPARK;GLLYDS(1)DEEDEERPARK 78.012 0.009467399999999999 73512000.0 80512.0 52794.0 56312.0 45586.0 53776.0 46503.0 44644.3 43947.0 56782.0 39071.0 True False 79363.88411590732 52671.758736653675 51682.244730606115 48938.546510438115 50613.00140768384 44514.17509378766 46955.76340776244 45988.938056411185 50386.613219032115 45824.370291164996 1.7319143419022343 1.1494267875800765 1.1278331682949614 1.0679589528341764 1.1044996600300714 0.9714083316573159 1.0246897689899206 1.0035912717228963 1.0995593152481733 1.0 15.48382743523975 -2.4321004012949876 1.174304924849246 1.0390222853881526 199.99999009247531 0.945339962509431 0.04888455115816103 89.11645550215721 0.5768900832392493 0.014720868946058433 47252.045746103955 0.003697426918498294 2.4321004012949876 198.96096780708717 GLNNDS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 1 GLNNDSPER 9 0 G5EA48;Q7Z6B7-2;Q7Z6B7 G5EA48 SRGAP1 SLIT-ROBO Rho GTPase-activating protein 1 1 GLNNDS(1)PER 87.789 0.010619 7527000.0 49795.0 38320.0 43586.0 38199.0 40180.0 44212.0 32219.0 30060.0 44883.0 24666.0 True False 49084.914168715375 38231.2723943738 40002.52732682551 41008.28188812849 37816.69139691939 42321.155823205794 33887.142171222265 31456.697339425227 39827.80390105701 28929.485234620966 1.6967088688454668 1.3215331031407724 1.3827597346582936 1.417525460807453 1.307202360851647 1.4629073237901422 1.1713703820304515 1.0873576589527372 1.3767201033149952 1.0 14.820253032023087 -1.5228787476547856 0.08716715948008737 0.7745076213147675 2.8815245379818486 0.5873121507498162 0.12150182723497718 120.7871433105564 0.7630429000931706 2.5133872741262273 30.467934841712115 0.029999999835978942 1.5228787476547856 2.107016916667081 GLNSSFET(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 3 GLNSSFETSPK 11 0 M0QZ79;M0QXD7;M0R025;M0QYG0;M0QYA8;Q8IV63-2;Q8IV63 M0QZ79 VRK3 Inactive serine/threonine-protein kinase VRK3 1 GLNSS(0.002)FET(0.499)S(0.499)PK;GLNS(0.001)S(0.01)FET(0.494)S(0.494)PK;GLNSSFET(0.5)S(0.5)PK 124.39 0.0012571 29634200.0 304629.0 240423.0 262372.0 317139.0 288537.0 267677.0 278727.0 271900.0 262437.0 275320.0 True False 401494.68532317487 318135.03302198625 258892.77584918056 244027.50329870684 248478.61806115843 250939.11487482334 303533.1630342531 229884.10264042363 276308.8840442461 265681.13060088584 1.5111900661334967 1.1974317946572512 0.9744492401987593 0.9184976845995596 0.9352512822388973 0.9445123720577342 1.1424716627325322 0.8652631902028542 1.0400019128920586 1.0 18.01933624176383 -4.867777999498102 2.0724696603788466 0.9728368249237337 1.607115315361502 0.8415818986984165 0.07196554900002382 0.20492335610171508 1.1521234493519745 0.01916508343316669 0.23238300309460186 1.3558823284472696e-05 4.867777999498102 0.6342784904377684 GLNSSFET(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLNSSFETSPK 11 0 M0QZ79;M0QXD7;M0R025;M0QYG0;M0QYA8;Q8IV63-2;Q8IV63 M0QZ79 VRK3 Inactive serine/threonine-protein kinase VRK3 1 GLNSS(0.003)FET(0.499)S(0.499)PK;GLNSSFET(0.686)S(0.313)PK 110.08 0.0048446 15618100.0 263500.0 252140.0 205840.0 272010.0 250730.0 245550.0 288760.0 274840.0 245120.0 228450.0 True False 308105.3456377718 277170.7928647916 210748.00625254735 256770.1615683187 201601.2563803646 232672.92573392985 261406.5623586416 267625.74121705076 248704.41627851923 269866.17659079545 1.1416967829390465 1.0270675501697728 0.7809352358080413 0.9514721882233705 0.7470415853041762 0.8621789090921809 0.9686525583197432 0.9916979763746313 0.9215842437921952 1.0 18.041884643821973 -5.015030769808295 5.102874828945673 0.8993607062641149 1.1209393714009905 0.4701574442989461 0.08119022465295735 0.138239987931973 10.996367318928659 0.021349474206244945 0.07252994840990415 9.659824366112057e-06 5.015030769808295 0.22157866513687563 GLNSSFET(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 1 GLNSSFETSPK 11 0 M0QZ79;M0QXD7;M0R025;M0QYG0;M0QYA8;Q8IV63-2;Q8IV63 M0QZ79 VRK3 Inactive serine/threonine-protein kinase VRK3 1 GLNSSFET(0.5)S(0.5)PK 105.65 0.0061911 15832000.0 233000.0 184150.0 159890.0 175920.0 189860.0 141280.0 184010.0 163740.0 167870.0 159700.0 True False 229677.377273033 183723.6119891426 146744.46139324846 188857.74365191636 178692.80807912187 135237.78373976544 193537.13743215537 171347.9581622585 148962.71285053232 187303.93221312633 1.2262282727289007 0.9808849703170683 0.7834563837467826 1.008295669078757 0.9540259297695567 0.7220231958925629 1.0332785603878114 0.9148123914840607 0.7952994424112414 1.0 17.515021661923953 -4.807961965000565 3.543965387984911 0.9012583990916757 1.2550437840932733 0.4883405774667693 0.09971217762921573 0.215725766927605 4.551368967919701 0.02436558640289923 0.19605884557437425 1.5561019072106093e-05 4.807961965000565 0.3537853850015976 GLNSSFETS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 GLNSSFETSPK 11 0 M0QZ79;M0QXD7;M0R025;M0QYG0;M0QYA8;Q8IV63-2;Q8IV63 M0QZ79 VRK3 Inactive serine/threonine-protein kinase VRK3 1 GLNSSFET(0.059)S(0.941)PK 88.101 0.010011 12830000.0 81059.0 74673.0 51765.0 68528.0 62691.0 51009.0 59695.0 54668.0 53819.0 57009.0 True False 79903.08379560008 74500.09925639561 47509.08151867848 73567.77772270655 59003.63863524818 48827.46397778669 62785.71501012175 57208.0748553459 47757.33748080532 66862.9296902824 1.1950281593361423 1.11422128227838 0.7105444188393568 1.1002775089796673 0.8824566752991612 0.7302621079267947 0.9390212977647431 0.8556022764832618 0.714257327670555 1.0 16.028918949536806 -5.105068137285412 5.825304481464834 0.868600745810395 1.1761416823268789 0.48280785597925824 0.12038356542607266 0.17097274247123215 7.751643747050776 0.03000078521708448 0.08353909538243463 7.851124471650516e-06 5.105068137285412 0.30754093651648384 GLNVIGASDQS(ph)PLQSPSNLR ddPTM_PC-9_AZD4547_30min_R2 2 GLNVIGASDQSPLQSPSNLR 20 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;H0YGJ6 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 GLNVIGAS(0.001)DQS(0.999)PLQSPSNLR;GLNVIGASDQS(1)PLQSPSNLR 255.98 3.8116e-66 8902300.0 39668.4 38109.0 54797.0 85703.0 71137.0 67751.0 58659.0 86213.0 60025.0 69560.0 True False 52282.12604602264 50426.98898788746 54070.355976276274 65945.49744815068 61260.85546400153 63514.51925972021 63879.53736245968 72890.76182765294 63197.79895653381 67124.72557241615 0.7788802948567608 0.7512431307221558 0.8055207006834398 0.9824322838684341 0.9126421738277574 0.9462164458489869 0.9516543541551546 1.0859003326429426 0.9414980607757442 1.0 16.034556664455714 -5.697665072594267 4.050767692512893 0.9739113332504089 0.7678792999058589 0.8015903152590992 0.0448388272914104 0.09409975673310525 3.0594838537324125 0.01313380207516012 0.02315674239595622 2.0060184701216744e-06 5.697665072594267 -0.20603203334455 GLNVIGASDQS(ph)PLQSPSNLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLNVIGASDQSPLQSPSNLR 20 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;H0YGJ6 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 GLNVIGAS(0.185)DQS(0.62)PLQS(0.185)PS(0.01)NLR 69.229 0.004734899999999999 2680200.0 7709.8 4785.4 6402.3 2234.3 7495.5 6475.8 9989.3 5518.0 4880.3 8330.5 True False 9014.916864508914 5260.462886393169 6554.955112857961 2109.1194146983353 6026.810581896961 6136.1976480056355 9043.041187730896 5373.158346804278 4951.6651548794825 9840.753705798288 0.9160799196912345 0.5345589416889523 0.6661029539836673 0.21432498747078868 0.6124338401382704 0.6235495604762586 0.918937863712881 0.5460108552090223 0.5031794619513649 1.0 13.264553100833872 -7.01195124348032 21.827447034430882 0.7137773102129723 0.574073450759442 0.09730349759564971 0.213166846626413 294.2670148204344 537442.5057852811 0.07925679690251347 0.0649520614406488 9.728564363815443e-08 7.01195124348032 -0.13970385945353025 GLNVIGASDQS(ph)PLQSPSNLR ddPTM_PC-9_Lapatinib_30min_R1 2 GLNVIGASDQSPLQSPSNLR 20 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;H0YGJ6 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 GLNVIGASDQS(0.529)PLQS(0.471)PSNLR;GLNVIGAS(0.003)DQS(0.997)PLQSPSNLR 274.68 1.9250999999999997e-92 13324400.0 26928.0 28887.0 29362.0 25438.0 44727.0 40580.0 45970.0 36510.0 45042.0 46275.0 True False 26544.0017820096 28820.113926311984 26947.969700597674 27308.79537868039 42096.245796665346 38844.48799660026 48350.101667062496 38206.38788630787 39968.89564671274 54273.572092438364 0.4890778468901963 0.5310156087980679 0.49652102601059833 0.5031693018504152 0.7756306462557379 0.7157164435471578 0.890859027755036 0.7039593380961736 0.73643384995257 1.0 15.727962244383292 -6.27271971101167 5.588821327998157 0.7901562007495043 0.505135496245305 0.7498657342969898 0.08434981054544258 0.08585309050758261 9.99295365905163 0.024791409455806424 0.02964043664800905 5.336792151919886e-07 6.27271971101167 -0.28502070450419936 GLNVIGASDQSPLQS(ph)PSNLR ddPTM_PC-9_AZD4547_30min_R2 4 GLNVIGASDQSPLQSPSNLR 20 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;H0YGJ6 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 GLNVIGASDQS(0.008)PLQS(0.986)PS(0.006)NLR;GLNVIGAS(0.04)DQS(0.077)PLQS(0.816)PS(0.067)NLR;GLNVIGAS(0.005)DQS(0.309)PLQS(0.685)PS(0.001)NLR;GLNVIGAS(0.04)DQS(0.069)PLQS(0.889)PS(0.002)NLR 256.19 3.691699999999999e-66 28098200.0 44272.1 40325.1 59000.0 93875.0 79785.6 58988.7 85466.0 174326.0 139926.0 98973.0 True False 58349.70688311397 53359.39997468999 58217.62145008481 72233.56910429202 68708.7466397042 55300.12726389066 93072.30843041938 147387.9223129625 147322.2026954094 95507.98539503642 0.6109406102722215 0.5586904566564451 0.6095576323727 0.7563092112719406 0.7194031614792601 0.57901050928004 0.9744976615877438 1.5431999921613078 1.5425118861638742 1.0 16.543333741055875 -7.5451676347645815 3.5969815816124213 1.4027469702831163 0.6466590905293708 0.8125147038265591 0.15501352347530814 0.08813539513039732 2.4489702247954392 0.07588106852081426 0.04316029295101335 2.8499180058864575e-08 7.5451676347645815 -0.7560878797537456 GLNVIGASDQSPLQS(ph)PSNLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GLNVIGASDQSPLQSPSNLR 20 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;H0YGJ6 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 GLNVIGASDQS(0.004)PLQS(0.95)PS(0.046)NLR;GLNVIGASDQSPLQS(0.998)PS(0.002)NLR;GLNVIGASDQS(0.044)PLQS(0.956)PSNLR;GLNVIGASDQS(0.062)PLQS(0.938)PSNLR 230.0 2.9836e-36 22604000.0 61792.0 51665.3 54349.0 56914.0 115290.0 76179.0 83676.0 141239.0 93420.0 78052.0 True False 72252.1651523691 56794.28953992748 55644.88627973029 53725.2930976776 92699.75211619001 72184.03913453492 75749.60351822153 137531.6259050904 94786.09076672366 92202.20974070781 0.7836272618146303 0.6159753621919157 0.6035092481646105 0.5826898644703259 1.0053962087989148 0.7828883856203855 0.8215595236952075 1.4916304749295979 1.0280240683307078 1.0 16.492513706600576 -7.158474994117438 1.0825771462525835 1.1741804210113402 0.666467313695537 0.5100499389548502 0.18280904068833534 0.39337346673327617 0.9170135243796097 0.12216019888138764 0.0758506428875981 6.942645750487223e-08 7.158474994117438 -0.5077131073158032 GLNVIGASDQSPLQS(ph)PSNLR ddPTM_PC-9_Lapatinib_30min_R1 2 GLNVIGASDQSPLQSPSNLR 20 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;H0YGJ6 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 GLNVIGAS(0.001)DQS(0.068)PLQS(0.918)PS(0.013)NLR;GLNVIGAS(0.004)DQS(0.282)PLQS(0.693)PS(0.02)NLR 143.72 0.00015460000000000002 16065400.0 32466.0 28078.0 31345.0 27329.0 48997.0 42242.0 57838.0 37095.0 51698.0 69294.0 True False 32003.02888646478 28012.98711610718 28767.93509519905 29338.865826871464 46115.09279180834 40435.408130911506 60832.5686364925 38818.56912195538 45875.22683592551 81271.37557154898 0.3937798352913349 0.344684545070181 0.3539737686594536 0.3609987602712885 0.5674210934354118 0.49753566795868165 0.7485116156664194 0.47764134480264364 0.5644696735265454 1.0 16.31045969258077 -14.522878744949338 0.08875565823742655 2.725393071121165 0.033939431457765644 0.7960575052728689 0.08889380192110566 97.29082500220301 0.5992205714517697 31.72171390942048 2.290208370596901 3.0000000022864627e-15 14.522878744949338 -2.6914536396633992 GLPDFAS(ph)FSAK ddPTM_PC-9_AZD4547_30min_R2 2 GLPDFASFSAK 11 0 Q4VXZ8;Q9NUI1-3;Q9NUI1 Q4VXZ8 DECR2 Peroxisomal 2,4-dienoyl-CoA reductase 1 GLPDFAS(0.999)FS(0.001)AK;GLPDFAS(0.999)FS(0.001)AK 126.5 0.00040761 9488300.0 50681.0 47540.0 64693.0 66948.0 63371.0 61534.0 60166.0 68405.0 60785.0 59365.0 True False 66796.50376971284 62906.37530463063 63835.128550344736 51514.172936289244 54573.03051308376 57686.26925252204 65520.65744301387 57834.57904052288 63997.97100496299 57286.649419299734 1.1660047226851649 1.0980983517503053 1.114310737273436 0.899235222490325 0.9526308671614897 1.0069757934400625 1.1437334546038247 1.009564700096399 1.1171533272358258 1.0 15.80591133946096 -5.559810510965358 24.998181034838243 1.0197819019197145 1.125590042644728 0.3425842650822005 0.06850897457660815 199.56096748300536 135076.89677181255 0.019842924869320388 0.03436904737068674 2.7554306758060458e-06 5.559810510965358 0.10580814072501354 GLPDFAS(ph)FSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLPDFASFSAK 11 0 Q4VXZ8;Q9NUI1-3;Q9NUI1 Q4VXZ8 DECR2 Peroxisomal 2,4-dienoyl-CoA reductase 1 GLPDFAS(0.949)FS(0.051)AK 118.37 0.0010706 4504700.0 20861.0 24635.0 27127.0 27624.0 33378.0 23956.0 23100.0 20751.0 21613.0 22110.0 True False 24392.355276468945 27080.59999295686 27773.810559720398 26076.316838216346 26837.820505977823 22699.70518787222 20911.800770482772 20206.308237501908 21929.04923722113 26118.3679773363 0.9339157522259787 1.0368411998963916 1.0633823133137787 0.9983899783035278 1.0275458454856679 0.8691088665099382 0.8006549562602294 0.7736436003595452 0.8396025837544532 1.0 14.672777131542386 -6.829337995557159 4.434983013517359 0.8349682681894767 1.015884792113035 0.5814935316528511 0.06507420002910635 0.13295058739027216 5.076297618034189 0.02260094889491269 0.020194369890698394 1.48136474424542e-07 6.829337995557159 0.18091652392355828 GLPDFAS(ph)FSAKL ddPTM_PC-9_AZD4547_30min_R2 2 GLPDFASFSAKL 12 1 Q4VXZ8;Q9NUI1-3;Q9NUI1 Q4VXZ8 DECR2 Peroxisomal 2,4-dienoyl-CoA reductase 1 GLPDFAS(0.981)FS(0.019)AKL;GLPDFAS(0.971)FS(0.029)AKL 173.19 0.0017437999999999998 14477100.0 48741.0 48213.0 65674.0 85379.0 83655.0 68403.0 63061.0 73275.0 52428.0 67320.0 True False 64239.62412421947 63796.909393398346 64803.11984937068 65696.1906424006 72040.94724041 64125.74959665014 68673.30683465564 61952.03244198982 55199.23704611667 64963.14729061332 0.9888625598270792 0.9820477001830316 0.9975366427287343 1.0112839876508446 1.108951001375196 0.9871096501803234 1.0571117579547813 0.9536488767215472 0.8497007818784134 1.0 15.987333908479078 -7.954115445536095 6.346108906035687 0.917200252836738 1.0182137373730256 0.38339300980875735 0.049793260657839254 0.16887779142737297 16.342509378687254 0.027546186652575175 0.01285979144099658 1.111436242504229e-08 7.954115445536095 0.10101348453628756 GLPFGCSK ddPTM_PC-9_Lapatinib_30min_R1 1 GLPFGCSK 8 0 P31943;G8JLB6;E9PCY7;P55795;D6RBM0;E5RGV0;D6RIU0;D6RIH9;D6RJ04;D6RDU3;D6RIT2;D6RFM3;D6R9T0;D6RAM1;H0YAQ2;E5RGH4;P31942;P31942-2 P31943;P31942 HNRNPH1;HNRNPH2;HNRNPH3 Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;Heterogeneous nuclear ribonucleoprotein H2;Heterogeneous nuclear ribonucleoprotein H3 0 93.195 0.034125 7332900.0 65418.0 83007.0 76764.0 68665.0 68642.0 81292.0 72408.0 62408.0 78253.0 83843.0 False True 64485.12732380808 82814.80239143499 70452.76023760898 73714.8531597251 64604.61251536439 77815.33066090755 76156.93194493502 65307.703511605076 69439.3230993787 98335.15083622513 0.6557688352073262 0.8421688652246142 0.7164555058744597 0.7496287190579027 0.6569839163918286 0.791327719530396 0.7744629595552518 0.6641338621666785 0.7061495559713764 1.0 16.585419593391933 -11.012003954265369 3.2001606954168027 1.0062073596667176 0.7313647459143122 0.656296335648274 0.05889776974665744 70012532.47293851 93858444.60543665 3899362.583130931 0.014062592026154843 9.727383669222068e-12 11.012003954265369 -0.2748426137524054 GLPLGSAVS(ph)SPVLFSPVGR ddPTM_PC-9_Lapatinib_30min_R1 1 GLPLGSAVSSPVLFSPVGR 19 0 Q8WUM0 Q8WUM0 NUP133 Nuclear pore complex protein Nup133 1 GLPLGS(0.008)AVS(0.488)S(0.452)PVLFS(0.052)PVGR 189.9 3.072e-11 7833200.0 18350.0 20595.0 19116.0 16416.0 23784.0 23479.0 23524.0 22410.0 23926.0 23343.0 True False 18088.325635022124 20547.313542853037 17544.356269893924 17623.287402170652 22385.07188114311 22474.857902222207 24741.957616183998 23451.250411727175 21231.20192805048 27377.806447407635 0.6606930204495942 0.7505098548462649 0.6408240303545273 0.643707063822835 0.8176356978834117 0.820915216322976 0.9037231548741108 0.8565788664178294 0.7754895180822944 1.0 14.740719239796796 -6.4171848956717445 3.229784429711455 0.8624856038853143 0.6771720088604049 0.6915525154389905 0.062153268983115885 0.15496768901302865 3.058072180844228 0.02008354318534541 0.02273390764056571 3.826617949586628e-07 6.4171848956717445 -0.1853135950249094 GLPLGSAVSSPVLFS(ph)PVGR ddPTM_PC-9_AZD4547_30min_R2 2 GLPLGSAVSSPVLFSPVGR 19 0 Q8WUM0 Q8WUM0 NUP133 Nuclear pore complex protein Nup133 1 GLPLGS(0.003)AVS(0.133)S(0.133)PVLFS(0.731)PVGR;GLPLGSAVSSPVLFS(1)PVGR 198.98 4.95e-15 18002200.0 18401.8 15800.599999999999 25965.7 31947.0 27738.3 24744.1 21958.4 32784.0 26986.7 30616.3 True False 24253.189618782188 20907.8349524263 25621.377852313 24582.112726229778 23887.31584291031 23196.84751537899 23912.655060942634 27717.986101374187 28413.161867560022 29544.43265587646 0.8209055797846966 0.7076742747425099 0.8672150909358162 0.8320387469461302 0.8085217313577036 0.7851512258017614 0.8093793960936444 0.93817967074284 0.9617095105026015 1.0 14.850598674538302 -7.8294389536374025 3.1360555796088105 0.9746402343016378 0.8023806365958087 0.7827548758195745 0.03953795033905845 0.1180633620972936 2.3038814162035557 0.0253649383040144 0.01112986094869848 1.4810204194494766e-08 7.8294389536374025 -0.1722595977058291 GLPLGSAVSSPVLFS(ph)PVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLPLGSAVSSPVLFSPVGR 19 0 Q8WUM0 Q8WUM0 NUP133 Nuclear pore complex protein Nup133 1 GLPLGSAVSSPVLFS(0.999)PVGR;GLPLGSAVS(0.001)S(0.001)PVLFS(0.999)PVGR 166.21 8.6247e-08 35628000.0 11295.0 14584.8 12575.4 13037.7 15928.0 12412.2 14304.0 13252.7 13816.099999999999 12467.2 True False 13207.020413581164 16032.68255641474 12875.245228470072 12307.23993779371 12807.022740104703 11761.282381570703 12949.021568008044 12904.830667396343 14018.134325006744 14727.404669699103 0.8967649568802809 1.088629185928542 0.8742372140395004 0.8356692990934947 0.8696048643556669 0.7985984391241012 0.8792466736960115 0.8762460838702549 0.9518400994201207 1.0 13.846215594033778 -5.3025389462837635 23.675601227825783 0.8755604285720802 0.9926970741663924 0.2702183999000347 0.06875715813107489 258.43991218644044 148875.0131615498 0.017028119887852543 0.03544771068581361 4.982657709214259e-06 5.3025389462837635 0.11713664559431225 GLPLGSAVSSPVLFS(ph)PVGR ddPTM_PC-9_Lapatinib_30min_R1 1 GLPLGSAVSSPVLFSPVGR 19 0 Q8WUM0 Q8WUM0 NUP133 Nuclear pore complex protein Nup133 1 GLPLGSAVS(0.05)S(0.208)PVLFS(0.741)PVGR 89.913 0.0010284 11583000.0 9721.4 9155.4 8923.6 9627.4 10951.0 12796.0 9342.1 9512.4 9259.8 8186.9 True False 9582.77105331358 9134.201233806096 8189.936054092138 10335.431112064929 10306.883710494376 12248.7449089329 9825.788226753642 9954.3808307235 8216.863813983184 9601.99475664146 0.997997946904253 0.9512816310890191 0.8529411087656931 1.0763837487951313 1.0734106788972533 1.2756458651949116 1.023306976913041 1.0366992570828373 0.8557455010376656 1.0 13.22911843284674 -5.782157360263224 24.975191129202283 1.0596933117911398 0.9357943498829429 0.20298697519235198 0.10251183339419058 354.0808477359774 426837.4279040921 0.03045951137763108 0.04523456653610057 1.6513633424235398e-06 5.782157360263224 -0.12389896190819694 GLPNGPTHAFSSPS(ph)ESPDSTVDR ddPTM_PC-9_AZD4547_30min_R2 1 GLPNGPTHAFSSPSESPDSTVDR 23 0 Q9ULJ7-2;Q9ULJ7 Q9ULJ7-2 ANKRD50 Ankyrin repeat domain-containing protein 50 1 GLPNGPTHAFS(0.001)S(0.007)PS(0.456)ES(0.456)PDS(0.064)T(0.016)VDR 94.072 0.00088335 0.0 6867.4 9979.7 12394.0 17145.0 15702.0 13450.0 11476.0 13874.0 10629.0 12164.0 True False 9051.090349206315 13205.442861329877 12229.647461904255 13192.485137609465 13522.048336249087 12608.96937378395 12497.341768042192 11730.092092803363 11190.827240466426 11738.14206243345 0.7710837286740012 1.125002814848557 1.0418725039155736 1.1238989158114272 1.1519751817900399 1.074187832002603 1.0646780130595346 0.9993142041059591 0.9533729597873379 1.0 13.518916453292563 -10.60518189979231 12.540081257986541 1.0000028615105112 1.0440319978681998 0.0010662530646300405 0.10518865164938715 0.0 0.0 0.10066938871346769 0.024415913113646454 2.4820932882196188e-11 10.60518189979231 0.04402913635768857 GLPNGPTHAFSSPSES(ph)PDSTVDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLPNGPTHAFSSPSESPDSTVDR 23 0 Q9ULJ7-2;Q9ULJ7 Q9ULJ7-2 ANKRD50 Ankyrin repeat domain-containing protein 50 1 GLPNGPTHAFS(0.062)S(0.176)PS(0.269)ES(0.368)PDS(0.062)T(0.062)VDR 73.60300000000001 0.0039196 0.0 4004.6 4583.5 5350.0 4875.9 5679.1 7123.3 6085.8 4643.1 4472.8 3905.4 True False 4682.499685544682 5038.519588703782 5477.564289987987 4602.719130881083 4566.3211227604625 6749.741608147031 5509.308966623557 4521.223544771104 4538.206238293744 4613.41810487061 1.014974055917702 1.092144582209961 1.187311482608753 0.9976809008534842 0.9897913041828087 1.4630673948717114 1.1941924276941456 0.980015997248944 0.9836971493007622 1.0 12.171620331561487 -7.773883177021289 24.90406296631976 0.986392348058699 1.1364416179388215 0.20855616702448 0.130505880625285 382.24411166014096 764981.6389719533 0.07567772244674133 0.036756226881391844 1.6831267526090618e-08 7.773883177021289 0.15004926988012246 GLPPS(ph)MER ddPTM_PC-9_AZD4547_30min_R2 10 GLPPSMER 8 0 P38159;P38159-2;H3BUY5 P38159 RBMX RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed 1 GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER 144.65 0.0015577 450038200.0 2815939.4 2999365.6 4422464.0 5631672.0 4656657.1 4266272.4 3775476.6 4721963.3 3707389.8 4015194.8 True False 3711349.5540218675 3968851.8744088896 4363819.237773351 4333377.028865051 4010160.641417499 3999501.712402952 4111486.7033326933 3992292.371907004 3903354.8560417197 3874624.052182187 0.9578605573182349 1.0243192167698525 1.1262561680831074 1.1183993519124766 1.0349805780922094 1.0322296198389709 1.0611317763892747 1.030368964353728 1.00741512040203 1.0 21.88562490439117 -8.104664569534211 1.9221873816334905 1.0000209332958454 1.0542804581095095 0.1429946303106383 0.0452206351966899 0.7188984716490192 4.730480860472492 0.04409815090186616 0.0138084803092534 7.858423512693384e-09 8.104664569534211 0.05425952481366414 GLPPS(ph)MER ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 GLPPSMER 8 0 P38159;P38159-2;H3BUY5 P38159 RBMX RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed 1 GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER 91.265 0.0077972 442772500.0 4301638.0 5126128.0 5779033.0 6065579.0 6490269.0 5698763.0 5815933.0 5788987.0 5555523.0 4453919.1 True False 5029820.352176748 5635016.1104402635 5916827.063824699 5725744.2735024365 5218547.380235848 5399909.836181091 5265005.722531428 5637032.225188727 5636762.013858062 5261379.3756258 0.9559889133785359 1.071014976898529 1.124577157700387 1.0882591550094034 0.9918591699377585 1.0263296847965488 1.0006892388187072 1.071398168188213 1.0713468106807282 1.0 22.32700964973349 -6.246664026911077 24.76893340127437 1.0291643128400871 1.0653651932289518 0.09835173538866615 0.047591427797010005 1725.5440446382652 2892645.6919307383 0.014795489169924103 0.019033941179757857 5.666775049857945e-07 6.246664026911077 0.03620088038886471 GLPPS(ph)MER ddPTM_PC-9_Lapatinib_30min_R1 15 GLPPSMER 8 0 P38159;P38159-2;H3BUY5 P38159 RBMX RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed 1 GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER 128.86 0.0033068000000000004 535940200.0 4027313.0 3452291.0 3906592.0 3273851.0 3384892.0 3461381.0 3259550.0 3292569.0 3809055.0 2708662.0 True False 3969882.778101242 3444297.432297632 3585407.08564121 3514620.9237867743 3185799.3075137166 3313345.8035032135 3428313.5498993583 3445553.775854096 3380039.1147726453 3176850.617634748 1.2496284074751138 1.0841861474940881 1.1286042427486387 1.106322376090666 1.0028168431431097 1.0429655663098474 1.0791547864632776 1.0845816157447794 1.0639590971039037 1.0 21.599165822339252 -1.5228787536113948 0.7594825929911264 1.0563969757626839 35.13022100709486 0.6950178107751019 0.03732345525660821 237.44996247242827 0.9858465003085405 0.01411256787192119 13858.556011430781 0.02999999942451096 1.5228787536113948 34.07382403133218 GLPS(ph)PYNMSSAPGSR ddPTM_PC-9_Lapatinib_30min_R1 2 GLPSPYNMSSAPGSR 15 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 GLPS(0.995)PY(0.002)NMS(0.001)S(0.001)APGS(0.001)R;GLPS(0.998)PY(0.001)NMS(0.001)SAPGSR 104.09 0.0060581 0.0 15253.2 14514.2 13969.2 11643.9 16185.0 9325.5 11517.1 12447.0 12733.400000000001 9045.7 True False 15035.686570905702 14480.593261649788 12820.706298671377 12500.231248911732 15233.030120934303 8926.670103802258 12113.399084396902 13025.33306000751 11299.230403353586 10609.23719236239 1.417225979425733 1.3649042809670044 1.2084475128806647 1.1782403411539024 1.4358270858437014 0.8414054603500226 1.1417785147755355 1.2277351164685497 1.0650370237256948 1.0 13.373033309283928 -1.5228787452930572 0.24020248198822033 1.0354483249517878 3.412420400689826 0.421703592962132 0.1360514936138322 51.960182656179725 0.6944714652770655 0.1877432027161276 49.24711473962069 0.029999999999121358 1.5228787452930572 2.3769720757380384 GLPSPY(ph)NMSSAPGSR ddPTM_PC-9_AZD4547_30min_R2 1 GLPSPYNMSSAPGSR 15 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 GLPS(0.39)PY(0.559)NMS(0.039)S(0.012)APGSR 72.289 0.020905 14021000.0 24326.0 29892.0 30240.0 40596.0 32530.0 30417.0 25511.0 38185.0 26736.0 26359.0 True False 32061.161987767253 39554.00443008033 29838.997841535016 31237.21940194773 28013.771008672935 28515.020181590055 27781.429578644533 32284.38565400726 28149.210377374206 25436.17943305518 1.2604550959450571 1.5550293051746031 1.1730927563263776 1.2280625509880585 1.1013356421077958 1.1210417923272635 1.0922013524775511 1.2692309290778396 1.1066603163206716 1.0 14.634594370654645 -5.383314147087545 6.557844863405119 1.1438125428371901 1.4061832664233578 0.557782414765883 0.09669761955065659 0.1568491912857955 7.676030801791811 0.023885671633799437 0.05027435828216753 4.137003162726385e-06 5.383314147087545 0.26237072358616764 GLPSPY(ph)NMSSAPGSR ddPTM_PC-9_Lapatinib_30min_R1 2 GLPSPYNMSSAPGSR 15 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 GLPS(0.112)PY(0.793)NMS(0.073)S(0.022)APGSR;GLPS(0.096)PY(0.894)NMS(0.004)S(0.006)APGSR 86.014 0.005880699999999999 16318600.0 76276.0 80804.0 91499.0 72076.0 68597.0 72661.0 68751.0 60561.0 72913.0 52413.0 True False 75188.29025269455 80616.90330258285 83976.30541635418 77376.70947848764 64562.25932689096 69553.4584110638 72310.59037877344 63374.88514880011 64700.770132071615 61472.51721406749 1.22312040665041 1.3114300008546635 1.3660788466481877 1.2587203678195986 1.0502621700371237 1.1314561622530572 1.1763076193376663 1.0309466412137955 1.052515385155976 1.0 15.907653942184384 -6.169491392162001 4.51830511863548 1.083268689722318 1.302374530136396 0.769571698782852 0.058014130463750826 0.1134315263200526 4.006893508062425 0.018062191599828838 0.023580056010653185 6.76875208642588e-07 6.169491392162001 0.219105840414078 GLPSPYNMS(ph)SAPGSR ddPTM_PC-9_AZD4547_30min_R2 2 GLPSPYNMSSAPGSR 15 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 GLPSPY(0.005)NMS(0.86)S(0.134)APGSR;GLPSPYNMS(0.684)S(0.314)APGS(0.001)R 125.33 2.3529e-05 138363000.0 330526.0 278390.0 503797.0 619780.0 603280.0 480696.0 377591.0 540260.0 349187.0 437504.0 True False 435626.3926321132 368374.12328683434 497116.32260488765 476899.2965055463 519524.9853708036 450638.0031301456 411195.86750930856 456775.230939739 367644.3119406106 422187.1181258543 1.031832507268146 0.8725375727286443 1.1774786611482941 1.1295922495754176 1.2305562227408673 1.0673892778410403 0.9739659261387762 1.0819260259939385 0.870808928450099 1.0 18.687523033937907 -7.181390705148012 5.218538049739578 0.9886355985860404 1.0892503075371136 0.1990964369733167 0.10137375422103397 0.42989526475523293 20.448352661553848 0.0423469559014855 0.032398267729801894 6.585811480808461e-08 7.181390705148012 0.10061470895107316 GLPSPYNMS(ph)SAPGSR ddPTM_PC-9_Lapatinib_30min_R1 2 GLPSPYNMSSAPGSR 15 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 GLPS(0.004)PY(0.009)NMS(0.593)S(0.366)APGS(0.028)R;GLPSPY(0.001)NMS(0.781)S(0.213)APGS(0.004)R 119.65 8.266299999999999e-05 154433000.0 613460.0 490700.0 547980.0 414400.0 514060.0 540280.0 415280.0 482470.0 518340.0 415570.0 True False 604711.9479052151 489563.81429851707 502927.1996639702 444876.35839787463 483824.0014808456 517173.4838541946 436781.16641935485 504887.3175433303 459959.0908378201 487400.7207877822 1.2406874305147182 1.0044380186948403 1.0318556748358776 0.9127527708182791 0.9926616454297491 1.0610847743891123 0.8961438664132229 1.0358772484523302 0.9436980111444881 1.0 18.894748859015074 -4.6371355286846585 2.44529233289201 0.9830910163906342 1.3782785433767433 0.6907549171918608 0.05102318468991788 0.5584767563162887 2.790008242100259 0.012616103370315207 0.5446024594327273 2.306027442903087e-05 4.6371355286846585 0.39518752698610904 GLPSPYNMSS(ph)APGSR ddPTM_PC-9_AZD4547_30min_R2 1 GLPSPYNMSSAPGSR 15 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 GLPS(0.001)PYNMS(0.377)S(0.594)APGS(0.028)R 105.63 0.0009044000000000001 121040000.0 302940.0 324040.0 395020.0 603570.0 557610.0 414830.0 388230.0 510570.0 316240.0 433800.0 True False 399268.61845655716 428779.5930524293 389781.77669851755 464426.26156354265 480195.4765492191 388890.61452243885 422781.71789883374 431673.13823141216 332955.80078324396 418612.7940384431 0.9537898127879256 1.0242868807613474 0.9311272427634453 1.1094411546363112 1.1471113243259368 0.9289983967540305 1.0099589021639117 1.0311991042294077 0.7953789409328639 1.0 18.675256879708762 -8.227572854509381 24.491193456941417 0.8976893750410073 1.0186220950011733 0.2567797282053482 0.08114726444207267 567.8480005253139 410650.8238523849 0.05452405175479508 0.020605637656819806 5.921437442354904e-09 8.227572854509381 0.12093271996016597 GLPSPYNMSS(ph)APGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLPSPYNMSSAPGSR 15 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 GLPSPYNMS(0.168)S(0.829)APGS(0.002)R;GLPSPYNMS(0.062)S(0.934)APGS(0.004)R 115.58 0.00013888 96432000.0 223040.0 225040.0 285960.0 297240.0 326700.0 341110.0 344160.0 295610.0 300990.0 225110.0 True False 260796.26675919813 247380.48396245178 292778.37090933963 280586.6064650821 262685.4802355725 323221.5911101641 311558.6732973739 287850.55072468566 305391.4093328644 265920.6610302204 0.9807296121663901 0.9302792908383241 1.1009989587686344 1.0551515831001752 0.9878340374827805 1.215481301294719 1.1716226640319876 1.0824677917447454 1.148430543718295 1.0 18.020636347938677 -5.428289918885326 0.8135804167695125 1.118807494978407 0.9258805895335996 0.3411151515414653 0.07171170597305737 1.2776251060492576 1.1911082294744988 0.03074468728013478 0.1889846982314546 3.730010729857791e-06 5.428289918885326 -0.1929269054448074 GLPSPYNMSS(ph)APGSR ddPTM_PC-9_Lapatinib_30min_R1 1 GLPSPYNMSSAPGSR 15 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 GLPS(0.002)PY(0.01)NMS(0.09)S(0.542)APGS(0.355)R 82.55 0.006764399999999999 23287000.0 171720.0 139610.0 170410.0 165580.0 161520.0 139150.0 142140.0 135750.0 148300.0 137820.0 True False 169271.241310409 139286.74162261264 156399.5476016232 177757.30555868777 152019.7111605379 133198.87887449304 149499.31370363844 142057.44057973928 131596.8923317682 161642.00336639362 1.0471983629571964 0.8616989317243962 0.9675674907784497 1.0996974911017752 0.9404715853215152 0.8240363030676586 0.9248791192272509 0.8788398907537539 0.8141255960152745 1.0 17.302442611724437 -6.5264768279685175 24.55112876390217 0.8829927368683489 0.9873701448350148 0.3042114759065002 0.07487536729471904 108.33869440773971 739224.9117599812 0.024481934605438446 0.02459901588313934 2.9752480007116186e-07 6.5264768279685175 0.10437740796666595 GLPSPYNMSSAPGS(ph)R ddPTM_PC-9_AZD4547_30min_R2 4 GLPSPYNMSSAPGSR 15 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 GLPSPYNMSS(0.001)APGS(0.999)R;GLPSPY(0.001)NMS(0.011)S(0.039)APGS(0.949)R;GLPSPYNMS(0.093)S(0.332)APGS(0.575)R;GLPSPYNMS(0.004)SAPGS(0.995)R 124.5 2.9066999999999998e-05 47929900.0 39912.600000000006 45767.2 51316.3 79957.3 73672.8 71392.8 47219.1 66254.5 49242.700000000004 62146.0 True False 52603.9765663471 60560.55237362412 50635.81233252523 61524.379812970554 63444.60340509569 66928.59693001374 51421.50842448248 56016.38940194899 51845.568591035524 59970.28745577022 0.8771673239876332 1.00984262278698 0.844348334495988 1.0259143723189008 1.0579339552422167 1.1160292833242706 0.8574497573053538 0.9340690494982645 0.8645209284559974 1.0 15.871960267644463 -10.91850989950276 2.9753765355754176 1.0006398920997186 0.959041596666055 0.020226664081800516 0.09011890646428661 47101561.00863394 54773764.816212736 259763.0426101393 0.02306583147401804 1.2063965887398976e-11 10.91850989950276 -0.04159829543366356 GLPSPYNMSSAPGS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLPSPYNMSSAPGSR 15 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 GLPS(0.013)PY(0.041)NMS(0.056)S(0.115)APGS(0.775)R 62.236999999999995 0.038644 68796000.0 29980.0 31463.0 29342.0 33599.0 42738.0 31374.0 32777.0 28929.0 33019.0 25774.0 True False 35055.02186800915 34586.43870827689 30041.624560154673 31716.556959427722 34363.79569730003 29728.692209229554 29672.12527506987 28169.644402809146 33501.840409189135 30446.622173128275 1.1513599659323843 1.1359696491652973 0.9866981101985413 1.041710202829011 1.128657080640919 0.9764200455532845 0.9745621404681809 0.9252141088961666 1.100346705742529 1.0 14.893994560246309 -6.774018223257483 24.974961360978973 0.989337809489467 1.0831979449907325 0.36515219721479564 0.061208335344234865 264.4884108795877 525131.6585249677 0.02221037798458961 0.019715760895229344 1.68260345653685e-07 6.774018223257483 0.09386013550126548 GLPSPYNMSSAPGS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 2 GLPSPYNMSSAPGSR 15 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 GLPS(0.003)PY(0.205)NMS(0.205)S(0.205)APGS(0.382)R;GLPSPYNMSSAPGS(1)R 142.74 9.344799999999999e-05 43219000.0 92322.7 75265.6 91725.4 67655.2 90374.0 68541.2 54569.4 70163.4 83158.0 72939.6 True False 91006.16136809014 75091.32712750482 84184.09168228308 72630.7890991312 85058.37900212033 65609.85265334106 57394.73652187516 73423.44770808476 73791.8703474388 85547.11267409226 1.0638133599528383 0.8777774582945806 0.9840670134946358 0.8490150845398112 0.9942869647297875 0.7669440920033628 0.6709137775407003 0.8582808397964888 0.8625875034329066 1.0 16.384431542258717 -6.762216489757715 24.999950372829645 0.8128358229402592 0.9454299596660941 0.272762808680969 0.09673985791390903 26.159175437499613 841531.9250050026 0.032416236603179764 0.03027943772677707 1.7289542847076072e-07 6.762216489757715 0.13259413672583487 GLPSTAS(ph)GR ddPTM_PC-9_AZD4547_30min_R2 3 GLPSTASGR 9 0 P48730-2;H7BYT1;P48730 P48730-2 CSNK1D Casein kinase I isoform delta 1 GLPST(0.001)AS(0.999)GR;GLPST(0.001)AS(0.999)GR;GLPS(0.012)T(0.012)AS(0.977)GR 107.45 0.0025013 57723900.0 124978.0 131378.0 141073.0 152779.0 144864.0 129220.0 100016.0 120550.0 108992.0 183987.0 True False 164718.40429610986 173843.3692631841 139202.2798445393 117558.16196202018 124752.13413465697 121139.85297251769 108917.23024333474 101921.76746341687 114753.09460842186 177545.67113128465 0.9277522974599038 0.9791473267440979 0.7840364620414054 0.6621291367621843 0.7026481318286271 0.6823024870200404 0.6134603538871799 0.5740594339134952 0.6463300055542816 1.0 17.437830659838994 -5.457266540449923 2.9164635372349883 0.6759095856092852 0.9546584404112192 0.4444108891413864 0.11109352270770786 0.2061366732708256 3.4063620899122067 0.02911810287933888 0.06785812050186886 3.489261026125853e-06 5.457266540449923 0.278748854801934 GLPSTAS(ph)GR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLPSTASGR 9 0 P48730-2;H7BYT1;P48730 P48730-2 CSNK1D Casein kinase I isoform delta 1 GLPSTAS(1)GR;GLPST(0.001)AS(0.999)GR 122.94 0.0015260999999999999 39475000.0 78366.0 85910.0 99523.0 97365.0 122402.0 110085.0 92422.0 85047.0 90590.0 88667.0 True False 91631.8160009475 94438.57704058969 101896.0057630795 91909.95471158909 98418.2067701092 104311.94880643328 83667.119082665 82814.60636474525 91914.7073705575 104741.62521241425 0.8748366832681822 0.9016336804882477 0.9728320097806018 0.8774921577280976 0.9396284101045668 0.9958977492939451 0.7987953109662896 0.7906561140024191 0.8775375328018448 1.0 16.67647536993629 -7.270241307006574 24.991711481173265 0.8493019193167333 0.9262976521764765 0.15066204739809974 0.06505633189454245 950.4975035706367 2698779.964125749 0.02622155187494823 0.017971965092218743 5.367334883203662e-08 7.270241307006574 0.07699573285974326 GLPSTAS(ph)GR ddPTM_PC-9_Lapatinib_30min_R1 4 GLPSTASGR 9 0 P48730-2;H7BYT1;P48730 P48730-2 CSNK1D Casein kinase I isoform delta 1 GLPSTAS(1)GR;GLPST(0.008)AS(0.992)GR;GLPS(0.011)T(0.167)AS(0.822)GR;GLPS(0.018)T(0.057)AS(0.925)GR 123.11 0.0015157 64052000.0 237600.0 222041.0 203387.0 215034.0 202831.0 158974.0 255880.0 210802.0 195973.0 139814.0 True False 234211.78042949602 221526.87770665798 186665.30595652378 230848.31769239545 190900.87936108877 152175.05260649425 269128.2143695443 220596.6304905365 173900.45705282257 163980.6636095557 1.4282890145338316 1.3509329260559773 1.1383373005550284 1.4077776770196164 1.1641670131036372 0.9280060786241782 1.6412192050298624 1.3452600180700918 1.0604936778819622 1.0 17.32316617855274 -13.918655928012772 0.21096036192240414 1.4303210019860474e-11 1.3164098616903268 0.17472988671872158 0.1928807381798322 220.69902083326224 2.766746426198196 93.65005414345481 0.4239498762031407 1.2059910144364911e-14 13.918655928012772 1.3164098616760236 GLPTGDS(ph)PLGPMTHR ddPTM_PC-9_AZD4547_30min_R2 2 GLPTGDSPLGPMTHR 15 0 J3QQZ9;Q9NVS9-4;Q9NVS9-3;Q9NVS9 J3QQZ9 PNPO Pyridoxine-5-phosphate oxidase 1 GLPT(0.314)GDS(0.686)PLGPMTHR;GLPT(0.001)GDS(0.999)PLGPMTHR 105.06 0.00075321 22438900.0 79166.0 70709.0 227920.0 281330.0 213722.0 221002.0 126698.0 262660.0 169502.0 193472.0 True False 104339.14124490584 93564.30146014145 224897.63187971743 216473.7150051716 184050.38941025472 207182.71000334586 137973.87655345185 222071.93232634655 178461.52967480876 186698.6041682932 0.5588640670867191 0.5011515853423363 1.2046026422189584 1.1594822359252275 0.9858155620935904 1.1097175092781515 0.7390193256564463 1.1894675555590508 0.9558803638078653 1.0 17.51035161588947 -5.252229942610092 24.872176827133483 1.0434092066669376 0.53000774202856 0.7095358249398219 0.13128876606120818 314.4812304953719 849323.1966678128 0.03321025201832786 0.08520536072445645 5.5946130932202325e-06 5.252229942610092 -0.5134014646383775 GLPTGDS(ph)PLGPMTHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLPTGDSPLGPMTHR 15 0 J3QQZ9;Q9NVS9-4;Q9NVS9-3;Q9NVS9 J3QQZ9 PNPO Pyridoxine-5-phosphate oxidase 1 GLPT(0.039)GDS(0.961)PLGPMTHR;GLPT(0.008)GDS(0.992)PLGPMTHR 90.654 0.0028788 10286200.0 38522.0 56458.0 64410.0 58262.0 68528.0 58651.0 57479.0 54041.0 65988.0 39962.0 True False 45043.01375581887 62062.77712207667 65945.77867628523 54997.76902795254 55100.430332364165 55575.23831081542 52034.173008077036 52622.48101117251 66952.949662969 47206.79426098208 0.9541637906357128 1.3147000997136875 1.3969552414786937 1.1650392679472825 1.1672139825412042 1.1772720257929083 1.102260253479761 1.114722612178448 1.4182905387055216 1.0 15.526706894670662 -5.909980825647011 22.28146937072348 1.1664382955351165 1.2395118000444145 0.02857154450657995 0.14488348157451786 30.208836337541314 7460.7347612332815 0.040317266127410406 0.059800173950968045 1.230323089090464e-06 5.909980825647011 0.07307350450929806 GLPTGDS(ph)PLGPMTHR ddPTM_PC-9_Lapatinib_30min_R1 2 GLPTGDSPLGPMTHR 15 0 J3QQZ9;Q9NVS9-4;Q9NVS9-3;Q9NVS9 J3QQZ9 PNPO Pyridoxine-5-phosphate oxidase 1 GLPT(0.078)GDS(0.922)PLGPMTHR;GLPTGDS(1)PLGPMTHR 145.69 7.8268e-05 14625500.0 51267.0 57870.0 64820.0 62131.0 72796.0 76291.0 54220.0 73404.0 79049.0 63630.0 True False 50535.92317878364 57736.00557052224 59490.74981243584 66700.32100294023 68514.28240244261 73028.21177300719 57027.24629950246 76814.61781447682 70145.66919712705 74628.36071835445 0.6771678044692009 0.7736469756908699 0.797160077479826 0.893766396057734 0.9180729918618175 0.978558433684666 0.7641497917222361 1.029295258197795 0.9399331369726186 1.0 16.187436375877066 -3.4633231035265615 0.3677679872259679 0.9665009507568824 7.281562621238544e-16 0.6506371442362056 0.06589551979712795 10.256935037803016 0.5151824257987989 0.05494535147913782 5.332932145117911 0.0003440938388616289 3.4633231035265615 -0.9665009507568816 GLPWSCSADEVQR ddPTM_PC-9_Lapatinib_30min_R1 2 GLPWSCSADEVQR 13 0 P31943;G8JLB6;E9PCY7;D6RBM0;E5RGV0;D6RIU0;D6RIH9;D6RJ04;D6RDU3;E7EN40;D6RIT2;D6RFM3;D6R9T0;D6RAM1;D6RDL0;D6RF17;D6R9D3;E7EQJ0 P31943;E7EQJ0 HNRNPH1 Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed 0 ; 189.17 0.00011168 24469000.0 22501.0 19848.4 20354.0 27913.0 16204.7 23195.6 17774.0 18394.4 23707.4 18403.4 False True 22180.131613821955 19802.44224928206 18680.572688712105 29965.81513503834 15251.571405665982 22203.578259584567 18694.250751150077 19249.07097605867 21037.222962010514 21584.403169010926 1.027599949840926 0.9174421963037062 0.8654662601712381 1.3883087199770594 0.7066014884100621 1.0286862270744923 0.8660999613827504 0.8918046436278056 0.9746492778736635 1.0 14.397701580895841 GLQDS(ph)IR ddPTM_PC-9_Lapatinib_30min_R1 1 GLQDSIR 7 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 GLQDS(1)IR 76.847 0.030657999999999998 3642700.0 48062.0 48733.0 52588.0 32991.0 40679.0 40592.0 40593.0 49099.0 49310.0 31318.0 True False 47376.62706650867 48620.16173264659 48264.41763555039 35417.268194749784 38286.341197991125 38855.97478457362 42694.70691692559 51380.31878471189 43756.18854268028 36731.27457138812 1.289817127756649 1.3236720560336703 1.3139870096733868 0.9642264965762477 1.0423363099905694 1.0578444455842688 1.162352992514523 1.3988166592164668 1.1912515711274614 1.0 15.164721337854717 -5.7110789240957 24.998252656558954 1.129659740578491 1.3106107501758715 0.36222838147228553 0.11613994710076153 139.8395417164715 69413.23559941116 0.03516797360797853 0.06091261378885068 1.945006584533686e-06 5.7110789240957 0.18095100959738053 GLQGQAQVDS(ph)NSSLILR ddPTM_PC-9_AZD4547_30min_R2 1 GLQGQAQVDSNSSLILR 17 0 Q9P2J2-2;Q9P2J2 Q9P2J2-2 IGSF9 Protein turtle homolog A 1 GLQGQAQVDS(0.935)NS(0.032)S(0.032)LILR 73.252 0.010915000000000001 13748000.0 48211.0 35772.0 54103.0 92662.0 66182.0 66212.0 57800.0 65093.0 48566.0 65713.0 True False 63541.095148904315 47334.59944041328 53385.558869727814 71300.20751362896 56993.77168447562 62071.7531730099 62944.08802656317 55034.372538334275 51133.099610545956 63412.40787148059 1.0020293706191468 0.7464564275235759 0.8418787530971159 1.1243888996950686 0.8987794912312151 0.9788581644591099 0.9926146970184988 0.8678801891559413 0.8063579562248859 1.0 15.952477538892387 GLQLT(ph)PGIGGMQQHFFDDEDR ddPTM_PC-9_AZD4547_30min_R2 4 GLQLTPGIGGMQQHFFDDEDR 21 0 P12270 P12270 TPR Nucleoprotein TPR 1 GLQLT(1)PGIGGMQQHFFDDEDR;GLQLT(1)PGIGGMQQHFFDDEDR;GLQLT(1)PGIGGMQQHFFDDEDR;GLQLT(1)PGIGGMQQHFFDDEDR 99.40700000000001 0.00022999999999999998 46149700.0 107858.0 146942.0 127076.0 118064.0 106057.0 135923.0 108656.0 148830.0 112663.0 97488.0 True False 142154.6004142317 194438.12789257552 125390.88921001668 90846.16887061666 91332.81622707756 127423.7133228877 118326.1735054371 125831.74327316742 118618.13617392696 94074.97479303778 1.5110777412055407 2.066842200280508 1.332882517224937 0.9656783758961999 0.9708513494476838 1.3544910705872224 1.2577858645803652 1.3375687163349617 1.2608893750424428 1.0 16.521523377279074 -5.435530961794386 5.827013785873841 1.1792455445737755 1.7813534068142367 0.636663990039065 0.18589942277849414 0.1378819450377756 7.250477100840069 0.0494683802088774 0.10421647381256648 3.6683354115130495e-06 5.435530961794386 0.6021078622404612 GLQLT(ph)PGIGGMQQHFFDDEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GLQLTPGIGGMQQHFFDDEDR 21 0 P12270 P12270 TPR Nucleoprotein TPR 1 GLQLT(1)PGIGGMQQHFFDDEDR;GLQLT(1)PGIGGMQQHFFDDEDR;GLQLT(1)PGIGGMQQHFFDDEDR 92.38 0.00040637 15046000.0 16545.0 19603.7 19200.7 21240.4 46308.0 53825.0 73382.0 56091.0 53502.0 54269.0 True False 19345.741721354636 21549.82577966017 19658.517507060256 20050.36925030593 37234.279824759484 51002.32224650287 66430.72572032762 54618.670683327065 54284.365534160264 64107.54010683234 0.30177014574441363 0.3361511882026412 0.30664906927173025 0.3127614819862513 0.5808096795277159 0.7955744700468897 1.036238882503116 0.8519851267465184 0.8467703712183903 1.0 15.968206431167085 -6.609953354119323 1.9058292470473672 0.9223208221999116 0.31056927696601644 0.9566702806907832 0.059855351298627034 0.06397596261349468 0.4746872879119182 0.023509654903115716 0.02399260272833065 2.4549725805789664e-07 6.609953354119323 -0.6117515452338952 down GLQLT(ph)PGIGGMQQHFFDDEDR ddPTM_PC-9_Lapatinib_30min_R1 3 GLQLTPGIGGMQQHFFDDEDR 21 0 P12270 P12270 TPR Nucleoprotein TPR 1 GLQLT(1)PGIGGMQQHFFDDEDR;GLQLT(1)PGIGGMQQHFFDDEDR;GLQLT(1)PGIGGMQQHFFDDEDR 101.49 0.00016795 18702500.0 9547.7 15152.8 26191.0 18776.6 52672.0 84910.0 114710.0 103608.0 98987.0 118762.0 True False 9411.548047166261 15117.714622585248 24037.67708018368 20157.49380090141 49573.93651713633 81278.5972348775 120649.12251965926 108422.00591959945 87838.04168067931 139289.85345958205 0.06756808061326035 0.10853421298897395 0.17257306604288106 0.14471616776271892 0.3559048651847514 0.5835213062268189 0.8661730881543945 0.7783912699072545 0.6306133540887628 1.0 17.087730643383196 -6.71973388165402 1.5025313511454843 0.8081630086965409 0.11374359417448457 0.9213656995982118 0.09179290693807877 0.10025310073084359 0.4709485943422166 0.03984781961050724 0.03740239171336993 1.9066286661322365e-07 6.71973388165402 -0.6944194145220564 down GLQPS(ph)TPPPKPPR ddPTM_PC-9_AZD4547_30min_R2 1 GLQPSTPPPKPPR 13 1 A0A1B0GTL5 A0A1B0GTL5 1 GLQPS(0.987)T(0.013)PPPKPPR 101.3 0.0009607000000000001 22372000.0 254750.0 238040.0 316040.0 332770.0 346570.0 300530.0 292430.0 340890.0 284620.0 307310.0 True False 335755.200870825 314981.77487409103 311849.10310313234 256055.01774524958 298454.7377336544 281737.81159132323 318455.703488025 288213.2833729092 299664.43213675375 296551.17043788475 1.1321998843405403 1.062149828675408 1.0515861483286637 0.8634429510669646 1.0064190179824914 0.9500478827155251 1.0738642609900888 0.9718838167029861 1.0104982276558612 1.0 18.177921540312425 -5.275903952205194 2.4302845840166394 0.9844667135455953 1.1115014777636794 0.4230233254144764 0.053738389816807994 0.29299790696535305 3.2848236594515865 0.014667456626873259 0.04846523868175204 5.2978059627051945e-06 5.275903952205194 0.12703476421808402 GLQPS(ph)TPPPKPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLQPSTPPPKPPR 13 1 A0A1B0GTL5 A0A1B0GTL5 1 GLQPS(0.971)T(0.029)PPPKPPR 59.57 0.028727 5265800.0 57949.0 53694.0 59211.0 64145.0 64394.0 58555.0 69135.0 57153.0 59927.0 51222.0 True False 67758.62115507889 59024.38546871628 60622.81479896794 60551.163610895856 51776.45795619679 55484.272719813736 62586.03230594484 55652.79430860905 60803.31900425442 60508.14312687107 1.1198264837346819 0.9754783805703027 1.0018951444577704 1.0007109866838018 0.8556940484462392 0.916971995049931 1.0343406535334745 0.9197571009891756 1.004878283519037 1.0 15.884841691493678 GLQPST(ph)PPPKPPR ddPTM_PC-9_Lapatinib_30min_R1 1 GLQPSTPPPKPPR 13 1 A0A1B0GTL5 A0A1B0GTL5 1 GLQPS(0.246)T(0.754)PPPKPPR 87.51899999999999 0.0050880000000000005 26094000.0 300140.0 299680.0 288300.0 273830.0 309310.0 293910.0 263720.0 280090.0 337650.0 247880.0 True False 295859.948561065 298986.1093722837 264597.0868701831 293968.37167010177 291116.99392685725 281340.15443767357 277374.13120812987 293104.0039188166 299620.30138787243 290725.7277206618 1.0176600154401758 1.0284129709344427 0.9101261486029063 1.011153618824391 1.001345825872595 0.9677167433492293 0.9540749399194538 1.0081804806777883 1.0305943809546736 1.0 18.149299222596966 -7.9815005352469885 24.58052456012475 1.0166606164638388 0.984017190067037 0.13433887967095537 0.03351618607815349 359.7546099681191 478010.7346090484 0.01862757708009172 0.008945359282296877 1.043516846643681e-08 7.9815005352469885 -0.032643426396801734 GLQSS(ph)QGLT(ph)GFT(ph)LS(ph)LVS(ph)SLCRLVR ddPTM_PC-9_AZD4547_30min_R2 2 GLQSSQGLTGFTLSLVSSLCRLVR 24 1 Q8N0Z3 Q8N0Z3 SPICE1 Spindle and centriole-associated protein 1 5 GLQS(0.489)S(0.531)QGLT(0.98)GFT(1)LS(0.982)LVS(0.572)S(0.446)LCRLVR;GLQS(0.608)S(0.645)QGLT(0.748)GFT(0.999)LS(0.989)LVS(0.531)S(0.48)LCRLVR 60.728 0.009001100000000001 0.0 807.12 1198.45 3632.0 3307.8500000000004 3687.2799999999997 1174.3 2003.64 3251.4700000000003 3207.84 2142.8 True False 1063.767370861083 1585.8255255329113 3583.8373068933556 2545.2762882730517 3175.364819085755 1100.8708353631591 2181.9600784350014 2749.0300228475844 3377.3998734648467 2067.781224217558 0.5144487039549406 0.7669213294713917 1.7331801183413245 1.230921462320646 1.5356386748735005 0.5323923162034346 1.0552180534769333 1.3294588376426568 1.6333448789984273 1.0 11.013867838094042 -5.04250938860798 9.284832947572081 1.2448599935160847 0.576238483265755 0.36777837278332903 0.3299477152106774 0.42009840615886096 90.5055393821839 0.08670363791899273 0.23504041060583208 9.067563620506201e-06 5.04250938860798 -0.6686215102503297 GLQTSQDAR ddPTM_PC-9_Lapatinib_30min_R1 2 GLQTSQDAR 9 0 P27797 P27797 CALR Calreticulin 0 ; 117.81 0.0084574 20944800.0 55545.0 66803.0 73316.0 60938.0 70029.0 64729.0 64681.0 61643.0 67250.0 54006.0 False True 54752.918114294494 66648.32175786399 67288.24148794425 65419.583803208836 65910.03190231125 61960.691560668776 68029.86569343637 64507.15881883526 59675.596826105284 63340.86514152841 0.864416960392867 1.0522167894130499 1.0623195836936525 1.0328179707845124 1.0405609673161602 0.9782103768589869 1.0740280471608792 1.018412973594549 0.9421342239763623 1.0 15.950848952107672 -4.755561994824625 24.999999771192144 1.0252641507851163 0.8644167004196928 0.6052821513720756 0.03818165168093779 131.27153544395432 558320.0769533014 0.0094985848052747 0.08374417574371426 1.755650260117117e-05 4.755561994824625 -0.16084745036542358 GLREEIIR ddPTM_PC-9_Lapatinib_30min_R1 1 GLREEIIR 8 1 E7ER60;A0A1W2PR85;O15056-2;O15056;O15056-3 E7ER60 SYNJ2 Synaptojanin-2 0 71.692 0.045001 1991400.0 6968.8 8955.6 7947.6 7712.9 9785.2 8081.2 6926.0 5999.1 7070.1 7154.3 False True 6869.4236340786 8934.863858430424 7294.179006623188 8280.132395480145 9209.653774443395 7735.585914197294 7284.594390821729 6277.840086791274 6273.7908865464215 8390.911222494478 0.8186743313006277 1.064826408182905 0.8692952187444012 0.9867977596143127 1.0975749272324584 0.9219005789811745 0.868152957129743 0.7481714345828792 0.7476888647954647 1.0 13.034611775278327 -7.299994537590055 2.9360735997259573 0.8124819324437751 0.9702647773332583 0.242881143490144 0.1020400578332126 0.31668927441302097 5.464932989301794 0.04525526329057909 0.029879512460285005 5.011935374313967e-08 7.299994537590055 0.15778284488948324 GLS(ph)APDLR ddPTM_PC-9_AZD4547_30min_R2 4 GLSAPDLR 8 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 GLS(1)APDLR;GLS(1)APDLR;GLS(1)APDLR;GLS(1)APDLR 134.23 0.0035428000000000005 178005000.0 762220.0 724100.0 1124950.0 1494920.0 1296110.0 1144040.0 1080750.0 1313950.0 1050800.0 1149670.0 True False 1004590.1048390996 958151.1644527349 1110032.4279707281 1150289.2902837633 1116167.4989871243 1072502.9979467527 1176934.6563098272 1110909.2190672462 1106343.1427492835 1109420.4032323146 0.9055089503602148 0.8636502102008812 1.0005516616934667 1.0368380524933347 1.0060816402286743 0.9667237007918708 1.0608554276456506 1.001341976252279 0.997226244916656 1.0 20.08137473259469 -5.290274827890648 7.938319202240614 1.010176869510991 0.8845604045078266 0.7913079619969399 0.025490478608016065 0.09062685855187384 22.536779117056987 0.006554570331864385 0.014069089622473357 5.12536940484795e-06 5.290274827890648 -0.12561646500316437 GLS(ph)APDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GLSAPDLR 8 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 GLS(1)APDLR;GLS(1)APDLR;GLS(1)APDLR 122.94 0.0033068000000000004 43024900.0 283233.0 316203.0 406740.0 364992.0 432974.0 393822.0 417465.0 429871.0 375766.0 281266.0 True False 331178.75279325637 347593.54412717355 416438.22417004 344542.6815600302 348135.8528298646 373169.2810359918 377919.6930151341 418587.34173597256 381260.8668705696 332257.29929956986 0.9967538816796887 1.0461577363685732 1.2533606486537137 1.0369755074948213 1.0477899313687562 1.1231334325014628 1.1374308218715583 1.2598288814674492 1.1474868051787093 1.0 18.341941368588728 -7.080687292750398 3.131665807116185 1.157644186701804 1.0824129295478302 0.0736882405846202 0.08782775300839281 0.5669254217134878 10.761500832915628 0.03618313009256369 0.02788213876110109 8.3044850432437e-08 7.080687292750398 -0.07523125715397372 GLS(ph)APDLR ddPTM_PC-9_Lapatinib_30min_R1 4 GLSAPDLR 8 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 GLS(1)APDLR;GLS(1)APDLR;GLS(1)APDLR;GLS(1)APDLR 131.12 0.003423 164845000.0 934280.0 815620.0 965840.0 840040.0 881060.0 848120.0 762530.0 746690.0 929200.0 725650.0 True False 920956.995874033 813731.482001544 886432.3634502173 901819.3438912912 829237.7830306062 811847.8846642828 802010.072312056 781383.9433258636 824543.7110902149 851077.6356321524 1.0821069163566688 0.9561189813161182 1.0415411313114866 1.0596205400479703 0.9743385894691918 0.9539057903469276 0.9423465483455564 0.9181112399287491 0.9688231444100526 1.0 19.698931215552278 -6.447577217624251 4.538637959804143 0.9516166984060762 1.0294113300833116 0.5086285186173671 0.03620034611214775 0.18415641974666894 7.040701552149054 0.01136540231967151 0.012723704530442368 3.567983048511269e-07 6.447577217624251 0.07779463167723544 GLS(ph)DHVSLDGQELGTR ddPTM_PC-9_Lapatinib_30min_R1 1 GLSDHVSLDGQELGTR 16 0 Q7L8J4;Q7L8J4-2 Q7L8J4 SH3BP5L SH3 domain-binding protein 5-like 1 GLS(0.503)DHVS(0.497)LDGQELGT(0.001)R 54.281000000000006 0.039806 10983000.0 50415.0 37027.0 61173.0 43385.0 54835.0 62048.0 44778.0 50676.0 57206.0 36689.0 True False 49696.07285502129 36941.26625643209 56143.59207460874 46575.67762811734 51609.71310975795 59394.35168095253 47096.38573956329 53030.59196183341 50762.85787411415 43030.64476498047 1.1548995634726191 0.858487397950772 1.304735087778651 1.0823839122676107 1.1993711317047093 1.3802803096571143 1.0944847793192174 1.2323912934948902 1.179690849425207 1.0 15.393076837132229 -6.266763492896259 22.805269114142096 1.1982905868726934 1.0974814539408753 0.06872324228474402 0.13723047881401665 306.36953329720245 1312300.382436557 0.04102589654747409 0.04800313299611439 5.410488859069833e-07 6.266763492896259 -0.10080913293181815 GLS(ph)EDTTEETLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLSEDTTEETLK 12 0 P19338;H7BY16 P19338 NCL Nucleolin 1 GLS(0.773)EDT(0.008)T(0.027)EET(0.191)LK 95.417 0.014509000000000001 0.0 5580.6 6827.0 6035.6 5495.1 10134.0 5674.2 9667.8 5017.0 7606.1 6026.1 True False 6525.285358125814 7504.739441928815 6179.511594140468 5187.2273623545725 8148.315447527693 5376.634963141787 8751.995995189329 4885.309065950897 7717.324823172524 7118.584227418651 0.916654934416927 1.0542460694674105 0.8680815449705356 0.7286880644573859 1.1446539349977523 0.7552955463296482 1.2294573914682734 0.6862753758161844 1.084109505011924 1.0 12.797374625406883 -6.259869723365335 24.99991779733678 0.9685201719921699 0.901809974966184 0.058875025949422066 0.17121799748872463 617.1454792586227 9829302.918387832 0.04911544212045745 0.06001605163246775 5.497057460298481e-07 6.259869723365335 -0.0667101970259859 GLS(ph)GPCRPPPPPQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLSGPCRPPPPPQAR 15 1 Q9UEE5 Q9UEE5 STK17A Serine/threonine-protein kinase 17A 1 GLS(1)GPCRPPPPPQAR 55.54600000000001 0.033025 11495000.0 8841.8 8490.6 8190.6 12828.0 22667.0 12259.0 12034.0 8979.4 9694.2 10842.0 True False 10338.542106489775 9333.490655579442 8385.894967023474 12109.28874893714 18225.564066420975 11616.116459263883 10894.052401384839 8743.70026446073 9835.959335375428 12807.56877477522 0.8072212836250198 0.728748041077238 0.6547608772977799 0.9454791117566859 1.4230307396292583 0.9069727958160234 0.8505948781505596 0.6826978967063314 0.767980208292737 1.0 13.644709018424553 -5.7738162322916144 24.627955990484494 0.941398513847709 0.7300938736025647 0.20645501836036584 0.18800964585367738 323.94296582792947 644594.6281199582 0.059447183808745585 0.08890672630718927 1.6833862197561532e-06 5.7738162322916144 -0.21130464024514428 GLS(ph)GPCRPPPPPQAR ddPTM_PC-9_Lapatinib_30min_R1 1 GLSGPCRPPPPPQAR 15 1 Q9UEE5 Q9UEE5 STK17A Serine/threonine-protein kinase 17A 1 GLS(1)GPCRPPPPPQAR 99.927 0.0094939 14425000.0 11172.0 11630.0 11682.0 11066.0 14182.0 11892.0 11606.0 10756.0 14996.0 8298.9 True False 11012.685231306123 11603.071449545077 10721.55105382406 11879.830555093846 13347.842642884789 11383.40688160597 12206.901891405858 11255.763026708502 13306.992565119328 9733.353807410844 1.1314378835095067 1.192093874231784 1.1015269007955732 1.2205279691003017 1.3713508115488335 1.1695256441760904 1.2541311179001515 1.1564115770802985 1.3671538945792316 1.0 13.24872128264102 -5.874766938719184 7.3951433858053965 1.23283975819909 1.147178052714633 0.09923058286565611 0.1030159228379875 0.4567670109001757 27.8029629501438 0.02725115913255316 0.04064670558648716 1.3342372497321585e-06 5.874766938719184 -0.08566170548445706 GLS(ph)LEHQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLSLEHQK 8 0 A0A087WXN9;Q765P7 A0A087WXN9 MTSS1L MTSS1-like protein 1 GLS(1)LEHQK 105.2 0.007818 0.0 26772.0 22445.0 21436.0 26371.0 25279.0 27825.0 32154.0 35162.0 26614.0 18145.0 True False 31303.970828897316 24673.191266162645 21947.115536482714 24893.518365935535 20325.761416819874 26365.808016886982 29108.140345199292 34239.034757218564 27003.17940125865 21434.54486425903 1.4604448579216174 1.151094712876497 1.023913298624706 1.1613737788034006 0.9482711923924265 1.2300614817742443 1.3580013258753898 1.5973763368454044 1.2597971905755285 1.0 14.387650163205494 -7.075713830712577 4.589164821408002 1.350380916430326 1.1383871150248122 0.11076115073529103 0.18618310879588673 0.35313496602402555 13.732746232472524 0.07172871318056909 0.05588456876933959 8.400133134440224e-08 7.075713830712577 -0.21199380140551383 GLS(ph)LEHQK ddPTM_PC-9_Lapatinib_30min_R1 2 GLSLEHQK 8 0 A0A087WXN9;Q765P7 A0A087WXN9 MTSS1L MTSS1-like protein 1 GLS(1)LEHQK;GLS(1)LEHQK 70.1 0.022136000000000003 18491400.0 133629.0 110045.0 118722.0 126263.0 147571.0 107269.0 139393.0 131595.0 152822.0 207966.0 True False 131723.42595544236 109790.19756364451 108961.13544017311 135548.8022210207 138891.16391574874 102681.35492625218 146610.0874848129 137709.38411116626 135609.5770729971 243912.64600272375 0.5400434463491139 0.4501209730733621 0.4467219606110802 0.5557268327100475 0.5694299422023316 0.42097593793929633 0.6010762044833695 0.5645848477640166 0.5559759991758803 1.0 17.896005033113987 -14.522878745270432 0.250909101022291 3.9420342610190375 0.4790830966262068 0.8824039090627293 0.05301099792055271 56.54619907794531 0.559197129311404 85.25044624623736 0.07574884882674439 3.000000000068422e-15 14.522878745270432 -3.462951164392831 GLS(ph)PAQADSQFLENAK ddPTM_PC-9_AZD4547_30min_R2 2 GLSPAQADSQFLENAK 16 0 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 GLS(1)PAQADSQFLENAK;GLS(0.992)PAQADS(0.008)QFLENAK 127.83 2.3144e-05 6988200.0 26536.0 32184.0 31409.0 35940.0 35800.0 39047.0 32290.0 39278.0 30238.0 38318.0 True False 34973.89601691159 42586.84860757746 30992.496137723967 27654.588267464787 30829.787952981616 36605.384917333984 35163.74744598141 33208.4876186486 31836.318947899515 36976.498483091484 0.945841208650526 1.1517274581056254 0.8381674146862806 0.7478963504375787 0.8337671012056315 0.9899635287011505 0.9509755895913453 0.8980971422654876 0.8609879316306152 1.0 15.174320993684326 -5.273846662964133 24.99063918430966 0.8850094577617343 1.0487843399677161 0.3512682367395109 0.08611189333093983 728.859599601664 1468062.8197010811 0.023534834164100103 0.04955441092548131 5.322961647369829e-06 5.273846662964133 0.1637748822059818 GLS(ph)PAQADSQFLENAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLSPAQADSQFLENAK 16 0 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 GLS(1)PAQADSQFLENAK;GLS(1)PAQADSQFLENAK 217.88 3.6091e-22 5744000.0 15627.400000000001 23271.0 21131.0 25137.0 26038.0 20353.0 22172.0 19559.699999999997 17650.2 17809.5 True False 18272.810164780738 25581.1910873188 21634.843179763775 23728.655385253573 20936.040815346973 19285.652850591232 20071.70764862097 19046.278600215213 17908.300784102186 21038.221370075564 0.8685529942550988 1.2159388684684669 1.0283589472319574 1.127883149808702 0.9951430991750124 0.9166959749754722 0.954059152413457 0.9053179099686792 0.8512269392494687 1.0 14.360725119871786 -6.55037100816641 3.7488138021104547 0.921974462858504 1.0691612093439797 0.333162636335965 0.089217555886504 0.23534230734910688 7.169725129420293 0.028466269085884777 0.02957405910917922 2.815976277209651e-07 6.55037100816641 0.1471867464854757 GLS(ph)PAQADSQFLENAK ddPTM_PC-9_Lapatinib_30min_R1 2 GLSPAQADSQFLENAK 16 0 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 GLS(0.987)PAQADS(0.013)QFLENAK;GLS(1)PAQADSQFLENAK 239.18 2.6589000000000003e-37 7511700.0 22370.0 28488.0 27401.0 22948.0 25408.0 26701.0 23211.6 23731.0 29185.0 21723.3 True False 22050.99969784443 28422.037786297486 25148.19555091878 24635.672472283895 23913.551394049955 25559.060473071077 24413.383072768927 24833.62889427477 25897.877968325363 25478.143460522228 0.8654869116351402 1.1155458728904935 0.9870497663962566 0.9669335801667135 0.9385908133810232 1.003175938336097 0.9582088706972264 0.9747032366292263 1.0164742972129623 1.0 14.63697253477785 -8.257519605896915 23.465550739389663 1.0082371476806942 0.9799529932899181 0.04232817128858557 0.05881665227632443 545.3077869553782 3264577.9386933735 0.041525429261620346 0.014341057124516809 5.526884566776022e-09 8.257519605896915 -0.02828415439077603 GLS(ph)SAGGGSPHREDAQPEHSASAR ddPTM_PC-9_AZD4547_30min_R2 1 GLSSAGGGSPHREDAQPEHSASAR 24 1 Q92994-8;Q92994-9;Q92994-3;Q92994-7;Q92994-5;Q92994 Q92994-8 BRF1 Transcription factor IIIB 90 kDa subunit 1 GLS(0.349)S(0.349)AGGGS(0.302)PHREDAQPEHSASAR 46.971000000000004 0.01874 6416700.0 9955.5 3218.0 18994.0 33883.0 15748.0 21618.0 14549.0 17550.0 13530.0 19601.0 True False 13121.141912736033 4258.155568580171 18742.127149540862 26071.797837131613 13561.662030266874 20266.2230425622 15843.832814852378 14838.050758879863 14245.168177957554 18914.77495608006 0.6936980187817835 0.2251232477503735 0.9908723309190787 1.3783826610504275 0.7169877549036102 1.071449334693127 0.8376432102227819 0.7844687971881075 0.7531238521755986 1.0 14.207225991163876 -5.275745922087875 24.625787636318687 0.9424184359881133 0.45941063203902716 0.4554916416106123 0.21088759936800186 500.00891859157053 860663.3861509518 0.0556309152248172 0.11670599032953632 5.299734067419348e-06 5.275745922087875 -0.4830078039490861 GLS(ph)SAGGGSPHREDAQPEHSASAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLSSAGGGSPHREDAQPEHSASAR 24 1 Q92994-8;Q92994-9;Q92994-3;Q92994-7;Q92994-5;Q92994 Q92994-8 BRF1 Transcription factor IIIB 90 kDa subunit 1 GLS(0.484)S(0.434)AGGGS(0.082)PHREDAQPEHSASAR;GLS(0.533)S(0.388)AGGGS(0.08)PHREDAQPEHSASAR 51.431000000000004 0.0094045 9488400.0 11051.7 12357.7 23525.8 18016.2 30479.0 24158.6 18443.7 18159.6 19070.6 15670.8 True False 12922.534528975217 13584.490786805882 24086.74429409334 17006.810723308485 24506.858745332203 22891.680487215293 16696.57921517547 17682.929741686658 19349.4714469694 18511.79199001546 0.6980704264581803 0.7338290530777802 1.3011568143745778 0.9187014813304567 1.323851238094629 1.2365999196383675 0.901942892626546 0.9552251749168391 1.045251127357403 1.0 14.176156938181649 -5.1762237582902015 8.148890225921813 1.0849282630315007 0.7112331129157102 0.5050670002899449 0.14631181213876485 0.2650083581500547 22.9574832356788 0.03825669993426643 0.10221291404028084 6.664633038488096e-06 5.1762237582902015 -0.37369515011579046 GLS(ph)WSIGGDGNLET(ph)HT(ph)T(ph)LPNILKK ddPTM_PC-9_AZD4547_30min_R2 1 GLSWSIGGDGNLETHTTLPNILKK 24 1 H7BZW4;H7BYX7;Q6P1J6-5;Q6P1J6-3;Q6P1J6 H7BZW4 PLB1 Phospholipase B1, membrane-associated;Phospholipase A2;Lysophospholipase 4 GLS(0.508)WS(0.508)IGGDGNLET(0.992)HT(0.993)T(0.999)LPNILKK 45.047 0.038187 0.0 0.0 0.0 0.0 650.07 544.22 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 500.20640498138135 468.6644469209959 0.0 0.0 0.0 0.0 0.0 0.0 GLSAS(ph)LPDLDSENWIEVK ddPTM_PC-9_AZD4547_30min_R2 2 GLSASLPDLDSENWIEVK 18 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YBW1;H0YC73 Q6PKG0 LARP1 La-related protein 1 1 GLS(0.229)AS(0.771)LPDLDSENWIEVK;GLS(0.003)AS(0.993)LPDLDS(0.004)ENWIEVK 164.58 1.55e-07 173248100.0 441274.0 412314.0 542799.0 651532.0 674690.0 589295.0 532824.0 591974.0 545425.0 624277.0 True False 581589.9529306104 545586.4372602754 535601.1306014342 501331.3634690566 581020.9394971274 552446.2904924917 580244.3037831404 500498.0205092389 574255.051992794 602421.2522451299 0.9654207097825906 0.9056560259568531 0.8890807364536567 0.832194019717387 0.9644761656926165 0.9170431627928308 0.9631869752613482 0.8308106970727891 0.9532450089578267 1.0 19.20041314080759 GLSAS(ph)LPDLDSENWIEVK ddPTM_PC-9_Lapatinib_30min_R1 3 GLSASLPDLDSENWIEVK 18 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YBW1;H0YC73 Q6PKG0 LARP1 La-related protein 1 1 GLS(0.005)AS(0.995)LPDLDSENWIEVK;GLS(0.001)AS(0.999)LPDLDSENWIEVK;GLS(0.193)AS(0.807)LPDLDSENWIEVK 186.98 1.0782999999999999e-10 412451400.0 1272566.4 1139930.2 1234248.1 997352.8 1111424.0 1207510.4 1114856.7 986943.3 1222178.4 1048477.3 True False 1254419.3697759048 1137290.7616590033 1132772.985553445 1070701.4519834062 1046052.2254636568 1155867.9950362237 1172578.5248902708 1032800.2887316562 1084523.7984828893 1229705.2042968173 1.0200976342888781 0.924848295091457 0.9211744258667255 0.8706976665969839 0.8506528408667028 0.9399553575909146 0.9535444111263941 0.8398763257428374 0.88193804067297 1.0 20.229881070845323 -4.571489705149035 1.7517634869741352 0.9006987909489234 1.1188292614741355 0.3340130327391835 0.046933735066759456 1.9189940583303335 3.797968664143514 0.012746546212443048 0.8318445348111895 2.6823181905916396e-05 4.571489705149035 0.21813047052521217 GLSAS(ph)LPDLDSENWIEVKK ddPTM_PC-9_AZD4547_30min_R2 1 GLSASLPDLDSENWIEVKK 19 1 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YBW1;H0YC73 Q6PKG0 LARP1 La-related protein 1 1 GLS(0.094)AS(0.901)LPDLDS(0.004)ENWIEVKK 67.785 0.0040857 7815200.0 14994.0 13066.0 21290.0 32092.0 33320.0 22520.0 15024.0 18931.0 14240.0 23255.0 True False 19761.78010542557 17289.328980443915 21007.68068936112 24693.68521645743 28694.093145065563 21111.82083997134 16361.106894655448 16005.648941102823 14992.697328463824 22440.849528271116 0.8806163991487738 0.7704400387633594 0.9361357137079646 1.100389946706259 1.2786544960749624 0.9407763646993196 0.7290769840973992 0.7132372114941019 0.6680984741498281 1.0 14.45383967167374 -7.185043765559508 5.048148478357142 0.7539514021009864 0.9940690158056955 0.30670694462419656 0.15160225175631814 0.27422789374883305 12.698811933970322 0.06506265355874488 0.04963404105609405 6.530647374344886e-08 7.185043765559508 0.24011761370470908 GLSAS(ph)LPDLDSENWIEVKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLSASLPDLDSENWIEVKK 19 1 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YBW1;H0YC73 Q6PKG0 LARP1 La-related protein 1 1 GLS(0.054)AS(0.673)LPDLDS(0.272)ENWIEVKK 47.281000000000006 0.036817 4503000.0 10643.0 5636.2 5698.2 15388.0 16956.0 27453.0 14988.0 24408.0 21054.0 15454.0 True False 12444.649691168159 6195.724687651853 5834.06669854384 14525.860248569117 13633.59351966446 26013.316351755544 13568.228136276879 23767.315862413696 21361.87491974525 18255.687866203312 0.681686156247604 0.3393859893453796 0.31957528751049835 0.7956895601540597 0.7468134654572114 1.4249430940322934 0.7432329165419009 1.3019129181329858 1.170149001029559 1.0 14.156058409454202 -6.251211086982819 1.7132884457524404 1.1176604170653923 0.4478015168931768 0.6291517564599614 0.2157457226980898 0.22211345403241678 1.288758404504786 0.07389956754590236 0.09947172127950923 5.607753473141854e-07 6.251211086982819 -0.6698589001722155 GLSAS(ph)LPDLDSENWIEVKK ddPTM_PC-9_Lapatinib_30min_R1 2 GLSASLPDLDSENWIEVKK 19 1 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YBW1;H0YC73 Q6PKG0 LARP1 La-related protein 1 1 GLS(0.028)AS(0.972)LPDLDSENWIEVKK;GLS(0.109)AS(0.886)LPDLDS(0.006)ENWIEVKK 68.676 0.0037949 10509100.0 69162.0 17683.4 23635.0 19879.1 17507.5 15019.0 13102.7 10518.8 21120.3 13536.2 True False 68175.73719724266 17642.45517376487 21691.821533738363 21341.075328733594 16477.74327106934 14376.672380999002 13781.093693996518 11007.541848767334 18741.509407381265 15875.914134147251 4.294287347561584 1.1112717683335156 1.3663352768507213 1.3442422999020518 1.0379083139299439 0.9055650124786481 0.8680504050065995 0.6933485376499604 1.1804995447204172 1.0 13.954552044116554 -4.761163890379774 7.043347790501604 1.0500187513576362 4.362400352966734 0.96056439860659 0.19685522973007305 0.021560422639906915 6.288063034224812 0.05592163771279389 0.34086226589189217 1.7331498328995304e-05 4.761163890379774 3.312381601609098 GLSAS(ph)TMDLSSSS ddPTM_PC-9_Lapatinib_30min_R1 1 GLSASTMDLSSSS 13 0 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 GLS(0.034)AS(0.806)T(0.161)MDLSSSS 63.943999999999996 0.038252 5393600.0 28300.0 15987.0 31263.0 18415.0 32036.0 24813.0 24685.0 22919.0 22817.0 17566.0 True False 27896.436810415616 15949.98308373836 28692.67681866987 19769.30053063917 30151.705465199317 23751.805831928108 25963.068515367355 23983.900409923044 20247.109186338195 20602.259694776287 1.3540474308985033 0.7741860999734163 1.3926956190123605 0.9595695240969945 1.4635144839400456 1.1528738198533819 1.260204894997528 1.1641393111845966 0.9827615750068358 1.0 14.33051496315488 -11.313766006389999 7.790544921294954 0.9960762334857127 1.1670341773514643 0.057231756423313906 0.2034735560890776 0.013077701249543867 0.00035102933599631686 0.18579931381147177 0.04424628311202719 4.855500393003641e-12 11.313766006389999 0.17095794386575158 GLSDHVS(ph)LDGQELGTR ddPTM_PC-9_AZD4547_30min_R2 2 GLSDHVSLDGQELGTR 16 0 Q7L8J4;Q7L8J4-2 Q7L8J4 SH3BP5L SH3 domain-binding protein 5-like 1 GLS(0.003)DHVS(0.997)LDGQELGTR;GLS(0.313)DHVS(0.687)LDGQELGTR 229.02 6.212399999999999e-29 27415000.0 18680.1 17874.6 44026.0 70546.0 50555.0 40915.0 34450.0 55013.0 35436.0 45465.0 True False 24619.983229782592 23652.21489314578 43442.18647392261 54282.709624834984 43536.31089282079 38356.57858203498 37515.98326150696 46512.00492297762 37309.074615972204 43873.284188468984 0.5611611641385477 0.5391029035241949 0.9901740268019489 1.2372611403251608 0.992319396601343 0.8742582027200066 0.8550985857440578 1.0601441351683027 0.8503825347494268 1.0 15.421055084654613 -5.261960104775193 24.88609066627557 0.985642707148739 0.5501319938508357 0.7185172362975176 0.10822218760112827 22.209895635543372 1061508.6258091961 0.030070841729670412 0.06939385501749111 5.470662152644747e-06 5.261960104775193 -0.43551071329790336 GLSDHVS(ph)LDGQELGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GLSDHVSLDGQELGTR 16 0 Q7L8J4;Q7L8J4-2 Q7L8J4 SH3BP5L SH3 domain-binding protein 5-like 1 GLS(0.003)DHVS(0.997)LDGQELGTR;GLS(0.215)DHVS(0.785)LDGQELGTR;GLS(0.054)DHVS(0.938)LDGQELGT(0.008)R 92.95200000000001 0.0028997 27933100.0 34326.7 32591.7 61920.0 64330.0 77323.0 69666.0 63640.0 49700.9 58691.0 44943.0 True False 40137.53232677085 35827.18858495845 63396.40763290765 60725.798660673965 62172.11321779984 66012.59232001616 57611.55848629977 48396.30403745642 59549.24484253674 53090.810131407736 0.7560165728762553 0.6748284401063155 1.1941126435251601 1.1438099835050264 1.1710522605308624 1.2433901866749646 1.0851512407458561 0.9115759190275736 1.1216488257599273 1.0 15.69617453577182 -5.257896948992754 24.997418871302752 1.1131143881861076 0.7154224674837928 0.7434791431851779 0.09240924985066623 150.34298087049953 1060894.4320375079 0.02556447878739404 0.06226572721050929 5.522084538086618e-06 5.257896948992754 -0.39769192070231485 GLSDHVS(ph)LDGQELGTR ddPTM_PC-9_Lapatinib_30min_R1 2 GLSDHVSLDGQELGTR 16 0 Q7L8J4;Q7L8J4-2 Q7L8J4 SH3BP5L SH3 domain-binding protein 5-like 1 GLSDHVS(1)LDGQELGTR;GLSDHVS(1)LDGQELGTR 234.36 6.3120000000000005e-37 17737800.0 38772.0 29211.0 53870.0 32725.0 45482.0 49392.0 32240.0 38464.0 52855.0 31213.0 True False 38219.10417008599 29143.36372421848 49441.01654421348 35131.7056673998 42806.83818105243 47279.61929837558 33909.22944846845 40251.177859735595 46901.913312175355 36608.12546129183 1.0440060420601858 0.7960900307510602 1.3505476153508793 0.9596696150024633 1.1693261438997993 1.2915061534185197 0.9262760390264425 1.099514857768279 1.2811886082986637 1.0 15.159876281109502 -5.2445941076400775 24.998413847276407 1.131442151140543 0.9200480552322813 0.2524812811795516 0.14768664168882015 1114.1227361750623 1653353.9321112332 0.035822598789233155 0.09423803132515467 5.693848302768718e-06 5.2445941076400775 -0.21139409590826175 GLSDIHHR ddPTM_PC-9_AZD4547_30min_R2 2 GLSDIHHR 8 0 D6R9T3;E7EMP6;Q96FZ2;D6RAI0;D6RGK7;D6RAZ3 D6R9T3 HMCES Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein 0 ; 139.88 1.6715e-08 586460.0 9550.099999999999 7942.9 23158.0 41685.0 29181.0 24937.0 16190.4 33460.0 19658.3 26394.3 False True 12586.833145579867 10510.287093124758 22850.909788831614 32075.16727683 25129.72185072503 23377.68544788478 17631.314235039245 28289.52583430883 20697.39760478513 25470.24359079965 0.4941779649930979 0.41264964960607126 0.897161022719304 1.2593192194053526 0.9866306052841354 0.9178430259037357 0.6922318654780365 1.1106892532636619 0.8126109014623414 1.0 14.636525136788498 -5.305126398216878 5.272510539718743 0.967121639506077 0.45143609677277474 0.6569189142356966 0.14666400718978082 0.10844445659758493 7.542055036982348 0.03970817561959405 0.0883825834774746 4.953060146500562e-06 5.305126398216878 -0.5156855427333022 GLSDIHHR ddPTM_PC-9_Lapatinib_30min_R1 1 GLSDIHHR 8 0 D6R9T3;E7EMP6;Q96FZ2;D6RAI0;D6RGK7;D6RAZ3 D6R9T3 HMCES Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein 0 113.26 0.0019135 0.0 8167.0 4706.2 9421.5 5619.7 6975.1 9453.3 5987.0 8298.0 10168.0 5079.8 False True 8050.537082355632 4695.303083048063 8646.900638041718 6032.9914847696455 6564.838331574228 9049.004395718615 6296.977565384014 8683.55537333834 9022.772766213206 5957.83666159197 1.35125172770421 0.7880885881476061 1.4513490599339816 1.012614448405773 1.1018828988541056 1.5188406312066747 1.0569234980841895 1.4575014164651572 1.5144377529481088 1.0 12.540572856262044 -6.714499247282566 24.999664176253912 1.3223467998045877 1.1315337825779754 0.11218885202588402 0.2348757286877671 243.51613833639496 129692.41463277981 0.07340236127311049 0.07340216419175073 1.9297486808193306e-07 6.714499247282566 -0.19081301722661226 GLSEDTTEETLK ddPTM_PC-9_Lapatinib_30min_R1 3 GLSEDTTEETLK 12 0 P19338;H7BY16 P19338 NCL Nucleolin 0 ;; 162.36 0.00090202 27351800.0 147703.0 119783.0 174495.0 127341.0 145158.0 148586.0 139117.0 152659.0 184369.0 138261.0 False True 145596.7281345869 119505.64982294536 160148.69467017896 136706.08193712338 136620.09183160833 142231.3231508833 146319.79755529106 159752.09444907928 163603.42172835965 162159.22962879762 0.8978627270731101 0.736964834480951 0.9876014768741747 0.8430360840394986 0.8425058021325612 0.8771090210311696 0.902321735803969 0.9851557312819716 1.0089060123365654 1.0 17.3070516145472 -7.682166368260528 1.9890345203906945 1.0068123894536813 0.8615503077920355 0.5170959873311172 0.0580521891228777 0.2690507365422365 2.101471955093797 0.038005456532788556 0.01680249780587982 2.078900155552732e-08 7.682166368260528 -0.1452620816616459 GLSEDTTEETLKESFDGSVR ddPTM_PC-9_Lapatinib_30min_R1 2 GLSEDTTEETLKESFDGSVR 20 1 P19338;H7BY16 P19338 NCL Nucleolin 0 ; 156.17 1.9507e-05 10636700.0 47349.0 35634.0 43287.0 37121.0 35552.0 41925.0 36415.0 38264.0 40184.0 35680.0 False True 46673.79457725685 35551.49166234642 39728.10995265209 39851.00217202587 33460.901257921294 40131.96548194843 38300.39052003656 40041.8851295997 35658.05476372063 41847.240459388435 1.1153374527181177 0.8495540272684919 0.9493603285790637 0.9522970149178687 0.799596362641741 0.9590110373202593 0.9152429192363595 0.9568584377375904 0.8521005058463955 1.0 15.35284486954566 -4.750019809686169 24.998473785305464 0.9135758767948606 1.1153378946580028 0.5076287295856038 0.059210521173812064 404.9097669844957 886328.3489196091 0.013866544168330323 0.2127645320904036 1.7781982983621768e-05 4.750019809686169 0.20176201786314218 GLSGY(ph)S(ph)MLAIGIGT(ph)LIYGHWS(ph)IMK ddPTM_PC-9_AZD4547_30min_R2 1 GLSGYSMLAIGIGTLIYGHWSIMK 24 0 U3KQP3;B4DEZ3;K7EJE1;E7ENQ6;Q9P0J0;Q9P0J0-2 U3KQP3 NDUFA13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 4 GLS(0.553)GY(0.601)S(0.85)MLAIGIGT(0.992)LIY(0.062)GHWS(0.942)IMK 40.872 0.026579000000000002 7879100.0 12848.0 13252.0 20399.0 30770.0 24274.0 22697.0 19704.0 26944.0 17956.0 21009.0 True False 16933.3967449985 17535.449843015675 20128.49593153018 23676.451891761033 20903.974099739527 21277.75300199066 21457.617828294136 22780.423911524707 18905.117502099456 20273.481304641926 0.8352485934974245 0.8649451754001748 0.9928485211329466 1.1678532924850922 1.031099384739277 1.0495362233184287 1.0584081493384703 1.1236562467595923 0.932504744400797 1.0 14.307306225122721 -5.3336145356675075 3.323729274039365 1.0574685092828195 0.8443133156480338 0.6276407072790617 0.061013004085373336 0.13918891336463943 2.9771985253927826 0.015754010826075315 0.039467216580487664 4.638584413344788e-06 5.3336145356675075 -0.21315519363478574 GLSHS(ph)PWAVK ddPTM_PC-9_AZD4547_30min_R2 1 GLSHSPWAVK 10 0 Q96KB5;Q96KB5-2;E5RFX4 Q96KB5 PBK Lymphokine-activated killer T-cell-originated protein kinase 1 GLSHS(1)PWAVK 94.616 0.0062337 6793800.0 32019.0 60677.0 57024.0 55066.0 54287.0 38176.0 43803.0 49939.0 40244.0 49481.0 True False 42200.37596342679 80289.65364659381 56267.824501180316 42371.38446121914 46750.18711182998 35788.84868502424 47701.38214234511 42222.07503405704 42371.21568024563 47748.68525084426 0.8838018416995185 1.681505013694051 1.1784162057150134 0.8873832701073158 0.9790884684307276 0.7495253219436329 0.9990093317072366 0.884256285010706 0.8873797353299158 1.0 15.543173388965888 -5.64450201272231 4.38215938636988 0.9075718035046393 1.3140983791746754 0.39118431833814526 0.19271509892860578 0.1789508311129661 5.947344329398129 0.0494892984223736 0.08854857581169627 2.2672425696658816e-06 5.64450201272231 0.40652657567003614 GLSHS(ph)PWAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLSHSPWAVK 10 0 Q96KB5;Q96KB5-2;E5RFX4 Q96KB5 PBK Lymphokine-activated killer T-cell-originated protein kinase 1 GLS(0.002)HS(0.998)PWAVK 94.82 0.0061551999999999996 3990000.0 31466.0 35924.0 42912.0 33247.0 36783.0 29327.0 32363.0 24271.0 26026.0 23512.0 True False 36792.57231817135 39490.297306554996 43935.18482466626 31384.278378228333 29575.63519897485 27789.040492767115 29297.342352170326 23633.91196725021 26406.581013645362 27774.539479110404 1.3246870338153949 1.4218164566241023 1.5818510639109062 1.1299657516133745 1.064847005698117 1.0005220973570998 1.0548272951278002 0.8509200300161802 0.9507477534778245 1.0 14.76147537049013 -5.943955984449266 3.894549461493013 0.9895116223641864 1.439320824401607 0.8581893712228947 0.08251806740847478 0.08163430514977274 2.5574869287447473 0.025934755480221814 0.03909987104367904 1.1377425896809301e-06 5.943955984449266 0.4498092020374205 GLSHS(ph)PWAVK ddPTM_PC-9_Lapatinib_30min_R1 1 GLSHSPWAVK 10 0 Q96KB5;Q96KB5-2;E5RFX4 Q96KB5 PBK Lymphokine-activated killer T-cell-originated protein kinase 1 GLSHS(1)PWAVK 94.616 0.0062337 3921600.0 35185.0 32458.0 41257.0 38884.0 37368.0 35073.0 32245.0 29167.0 34839.0 23289.0 True False 34683.255447861244 32382.845495213587 37865.0087166255 41743.65907322146 35170.08770831468 33573.009549156246 33914.48832400326 30522.20529936842 30915.064949065887 27314.472619358134 1.2697757680036903 1.1855563146499644 1.3862617537704192 1.5282615796739627 1.2875990028593547 1.229128968258483 1.2416307207032657 1.1174371083312413 1.131819946878856 1.0 14.737377947678464 -7.796858003390861 0.8681418028143119 1.025147662825902 1.3334503768064034 0.6022536853614624 0.08806806984973002 0.4549950049428416 0.6343837803092124 0.08874343024786695 0.037756347820940506 1.59640102003736e-08 7.796858003390861 0.30830271398050146 GLSQNQQIPQNS(ph)VTPR ddPTM_PC-9_Lapatinib_30min_R1 1 GLSQNQQIPQNSVTPR 16 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 GLSQNQQIPQNS(0.979)VT(0.021)PR 126.91 2.6448e-05 8951400.0 27153.0 23920.0 25937.0 16136.0 17477.0 20060.0 19269.0 16792.0 21577.0 13226.0 True False 26765.79324074965 23864.614709640406 23804.559979715334 17322.695268118052 16449.037221104034 19202.08056214395 20266.654536058897 17572.217622209857 19146.771044117075 15512.096477462777 1.7254787758467818 1.5384519264892942 1.5345804491546655 1.1167217334733484 1.0604006521621703 1.2378778452056611 1.3065064780575548 1.1328073963271301 1.2343122718412076 1.0 13.921106060974525 -5.687600660642239 4.5744051038420865 1.166575882185095 1.6088483665552065 0.8185465938822216 0.0960864570180732 0.08757682999527788 3.4279621406745897 0.02721210231574702 0.04780908087799542 2.0530491162096313e-06 5.687600660642239 0.4422724843701116 GLSQNQQIPQNSVT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 GLSQNQQIPQNSVTPR 16 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 GLSQNQQIPQNS(0.171)VT(0.829)PR;GLS(0.002)QNQQIPQNS(0.227)VT(0.771)PR 143.43 5.3455e-05 13696200.0 43063.0 45285.0 58480.0 88178.0 77350.0 62810.0 47269.0 76688.0 50240.0 59812.0 True False 56756.13823395634 59922.49065355905 57704.51698984683 67849.92443651949 66611.28765818776 58882.48077080816 51475.84942781337 64837.631714927506 52895.5838330072 57718.00008535592 0.9833351493472204 1.0381941606594656 0.9997663970427051 1.1755418471911716 1.1540816999840615 1.020175347096749 0.8918508845020379 1.1233520152992613 0.9164486599463405 1.0 15.816733691212837 -6.991753275967891 24.93393286539784 0.9878809178104759 1.0720258690304374 0.2078251405793201 0.08031463243892416 318.4301423745728 962766.5133024984 0.02905867895252385 0.025585336386228657 1.0191702173591068e-07 6.991753275967891 0.08414495121996146 GLSQNQQIPQNSVT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 GLSQNQQIPQNSVTPR 16 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 GLSQNQQIPQNS(0.003)VT(0.997)PR 235.02 1.4215000000000001e-36 8123900.0 29585.0 22877.0 25518.0 20049.0 20145.0 17294.0 21882.0 18830.0 23390.0 11876.0 True False 29163.112474775484 22824.02971205869 23420.008542328575 21523.470341503376 18960.11070659385 16554.37593428303 23014.942890551712 19704.910542294638 20755.571892380696 13928.750776224706 2.0937349618283534 1.638627187659753 1.6814148604270174 1.5452548966733086 1.3612211899833317 1.1885039943811804 1.652333598346553 1.4146933101803636 1.4901244358402077 1.0 13.76577825272465 -1.5228787452803385 0.45989079790768017 1.354016969387058 18.305114294892544 0.6278448876169601 0.17288439845905604 63.04965472619898 0.7424383989589357 0.10404785981179884 1009.7964846030723 0.029999999999999933 1.5228787452803385 16.951097325505486 GLSSAGGGS(ph)PHREDAQPEHSASAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLSSAGGGSPHREDAQPEHSASAR 24 1 Q92994-8;Q92994-9;Q92994-3;Q92994-7;Q92994-5;Q92994 Q92994-8 BRF1 Transcription factor IIIB 90 kDa subunit 1 GLS(0.231)S(0.231)AGGGS(0.537)PHREDAQPEHSASAR;GLS(0.233)S(0.233)AGGGS(0.534)PHREDAQPEHSASAR 46.595 0.019528 9149700.0 9733.599999999999 10764.0 23084.9 23463.4 26033.5 24479.1 17510.3 22561.2 20094.0 17554.2 True False 11381.306232636894 11832.578783202252 23635.33156597077 22148.821767369158 20932.422558043436 23195.372903007312 15851.597620406264 21968.99240556735 20387.836735886816 20736.637501029247 0.5488501321427831 0.5706122211286643 1.13978611840023 1.068100928430167 1.009441504535365 1.1185696283621696 0.7644246864815707 1.0594288685654527 0.9831794925708125 1.0 14.339894355963134 -5.250632137610521 24.44182712770869 1.0160271160883325 0.5597310503265395 0.7788503642178328 0.09764550736185082 232.2875692747054 525341.5085581946 0.02508532133209951 0.06488473621004782 5.615234043223243e-06 5.250632137610521 -0.45629606576179305 GLSSAGGGS(ph)PHREDAQPEHSASAR ddPTM_PC-9_Lapatinib_30min_R1 1 GLSSAGGGSPHREDAQPEHSASAR 24 1 Q92994-8;Q92994-9;Q92994-3;Q92994-7;Q92994-5;Q92994 Q92994-8 BRF1 Transcription factor IIIB 90 kDa subunit 1 GLS(0.204)S(0.204)AGGGS(0.593)PHREDAQPEHSASAR 47.472 0.017692 5056600.0 13371.0 10449.0 22461.0 15164.0 17118.0 17414.0 14559.0 11498.0 18595.0 10464.0 True False 13180.327088058904 10424.805982484642 20614.34328196732 16279.21114562109 16111.152895282874 16669.24381401669 15312.793782265888 12032.239055512682 16500.635285969176 12272.688457596438 1.0739559741615265 0.8494313221185037 1.6796925427702551 1.3264584367042032 1.312764758182266 1.3582389768640228 1.247713069159489 0.9804077645322347 1.3445004607572975 1.0 13.583163700236076 -7.551866626650644 23.64552366204372 1.1202842528547883 1.273996913057647 0.09509485647737814 0.21920761533663224 313.09416266149594 255386.07452745942 0.10684842451864167 0.061680413929065446 2.8062953287091007e-08 7.551866626650644 0.15371266020285868 GLT(ph)SVINQK ddPTM_PC-9_Lapatinib_30min_R1 2 GLTSVINQK 9 0 A0A5F9ZHM4;P07195 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain 1 GLT(0.896)S(0.104)VINQK;GLT(0.999)S(0.001)VINQK 94.69200000000001 0.013853 7436400.0 56531.0 58627.0 56650.0 46352.0 53669.0 53806.0 55675.0 60690.0 51547.0 42920.0 True False 55724.857573484274 58491.25278353216 51992.455675323814 49760.88070573918 50512.29493731375 51504.84280791215 58557.57908013281 63509.87895973773 45741.23404602598 50338.66481269484 1.106999118487368 1.161954791633276 1.0328532921717841 0.9885220613398162 1.0034492397695682 1.023166645352167 1.163272393060478 1.261652036184346 0.9086699898820232 1.0 15.619379330381877 -7.239431398751836 24.51148055554506 1.105202962248534 1.0517097683088916 0.0033240794097361137 0.10012200944492855 2045.581873984102 2278276.402760138 0.038957649546411316 0.030153182502464435 5.761938270705271e-08 7.239431398751836 -0.05349319393964236 GLTEQEVETILDK ddPTM_PC-9_Lapatinib_30min_R1 1 GLTEQEVETILDK 13 0 Q13618-3;Q13618-2;Q13618 Q13618-3 CUL3 Cullin-3 0 131.17 0.00080106 0.0 7233.5 5287.7 7325.9 5344.0 6478.6 6146.1 5556.6 6109.6 5602.5 5448.6 False True 7130.348963538562 5275.456655525319 6723.59278079179 5737.015587061403 6097.5414854176715 5883.245630258873 5844.293559347394 6393.474320191359 4971.487453059548 6390.383250196863 1.115793636214057 0.8255305588069076 1.052142339128825 0.8977576715582227 0.9541746162454076 0.9206404999383461 0.9145450797755134 1.0004837065123442 0.7779638964386676 1.0 12.641686741120457 -4.739167175428107 24.95243500659239 0.9302956021817914 1.1157943889050912 0.344705357375386 0.07796319613111888 1990.26035684774 2229650.633827869 0.017661904400307356 0.913149522598269 1.823193754955302e-05 4.739167175428107 0.18549878672329978 GLTLAQGGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLTLAQGGVK 10 0 A0A1B0GVU9;A0A0U1RR79 A0A1B0GVU9 0 75.652 0.020322 4599400.0 35501.0 68215.0 30954.0 53722.0 66457.0 64905.0 57530.0 49518.0 38842.0 42163.0 False True 41510.61812328867 74986.9343827707 31692.060753698715 50712.13050907397 53435.22791556625 61501.26754127759 52080.341918868995 48218.204968657854 39409.990768155425 49806.81813787567 0.8334324430920002 1.5055556083745647 0.6362996460839654 1.0181764747286648 1.0728496602141173 1.234796155237808 1.0456468384448838 0.9681045039893895 0.7912569451648235 1.0 15.604055628276614 -7.928484328872721 3.778522469944618 0.8906055221445591 1.0576019840852582 0.0725517013512258 0.22001315248605108 0.5712484944840929 15.96538572449139 0.13415149798253564 0.05720871884986801 1.179005065817711e-08 7.928484328872721 0.16699646194069906 GLTS(ph)VINQK ddPTM_PC-9_AZD4547_30min_R2 2 GLTSVINQK 9 0 A0A5F9ZHM4;P07195 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain 1 GLT(0.169)S(0.831)VINQK;GLT(0.004)S(0.996)VINQK 118.71 0.0017812000000000001 9642700.0 80202.0 98618.0 116535.0 157143.0 142003.0 129195.0 82151.0 127351.0 92404.0 107624.0 True False 105704.56769476745 130494.33991990033 114989.66975738376 120916.10918514806 122288.33460020213 121116.41622646948 89462.27985242567 107671.82918484927 97288.28679349518 103856.11651819594 1.0177981927164363 1.2564916183539108 1.1072017095616817 1.1642656517390881 1.1774784066644433 1.1661943493260647 0.8614059802318101 1.036740374997411 0.9367602992978266 1.0 16.664226659426447 -7.244192062812381 24.852047221811954 0.9617883622055681 1.1533512479202894 0.6333354761942268 0.0705616784965836 450.16473058206526 648653.4538984641 0.02507005024820109 0.01936918341375449 5.6991217802796384e-08 7.244192062812381 0.19156288571472135 GLTS(ph)VINQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GLTSVINQK 9 0 A0A5F9ZHM4;P07195 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain 1 GLT(0.024)S(0.976)VINQK;GLT(0.29)S(0.71)VINQK 103.34 0.0028868 4771300.0 53780.0 57701.0 55176.0 70155.0 71250.0 65239.0 73795.0 59885.0 53635.0 45783.0 True False 62883.89179658212 63429.1739473758 56491.60509614525 66224.44279557893 57289.073972404556 61817.75199330422 66804.60337046658 58313.08220340237 54419.31040754895 54083.09548197141 1.1627273039048671 1.1728096068117977 1.0445335015074482 1.2244943120471874 1.0592787535894994 1.1430143086745312 1.2352215193144016 1.0782127332715457 1.0062166361333666 1.0 15.722890107143739 -8.019207697232627 5.156484540555577 1.0123288235581005 1.1459798560837604 0.5053343260348749 0.057687288222114844 0.15504547665662385 11.919590365140502 0.03689890263282591 0.014710561040201003 9.567364117185085e-09 8.019207697232627 0.1336510325256599 GLTS(ph)VINQK ddPTM_PC-9_Lapatinib_30min_R1 1 GLTSVINQK 9 0 A0A5F9ZHM4;P07195 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain 1 GLT(0.051)S(0.949)VINQK 90.82700000000001 0.0082729 3565200.0 49206.0 43916.0 42916.0 28909.0 51991.0 49339.0 43271.0 46457.0 39694.0 37576.0 True False 48504.31341672476 43814.315200191 39387.61214055069 31035.064297596946 48932.99159823882 47228.885984826506 45511.36065337096 48615.5618196167 35223.243723649415 44070.961533127236 1.1005957603231566 0.9941765206837313 0.8937316266844741 0.704206652588429 1.1103227589317946 1.0716554470754065 1.032683632717226 1.103120062018011 0.7992392836079337 1.0 15.42754075299578 GLTSVINQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLTSVINQK 9 0 A0A5F9ZHM4;P07195 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain 0 128.12 0.0061754 6677100.0 42126.0 41198.0 47907.0 50623.0 57280.0 46067.0 53188.0 47633.0 43203.0 43435.0 False True 49257.0997735742 45287.86517190323 49049.28456830922 47786.7574319804 46056.395187920476 43651.16542368132 48149.64759222679 46382.68422133527 43834.762142954 51309.421668729214 0.9600010713742694 0.8826422847697803 0.9559508365732088 0.9313446902697069 0.8976206258038917 0.8507436646919905 0.938417273597372 0.903979867884643 0.8543218909378064 1.0 15.646936143914122 -4.7394515027567365 24.435317548328502 0.9100975145881843 0.9600013276481787 0.09265060671687708 0.04361092078094296 3204.533451061734 3560979.504596303 0.010433511770815017 0.5003402212502446 1.8220005227620693e-05 4.7394515027567365 0.04990381305999436 GLTSVINQK ddPTM_PC-9_Lapatinib_30min_R1 2 GLTSVINQK 9 0 A0A5F9ZHM4;P07195 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain 0 ; 140.35 0.0035914000000000002 40443000.0 200659.0 169683.0 151755.0 187579.0 159218.0 150496.0 145025.0 135151.0 148572.0 182101.0 False True 197797.56586364625 169290.10943879277 139278.28969124024 201374.18540520014 149853.11027463188 144059.63690331086 152533.68488722504 141430.60885298272 131838.25682748115 213576.91521566946 0.9261186568965599 0.7926423568195281 0.6521223960492049 0.9428649402574851 0.7016353341526192 0.6745093998470751 0.7141861971983109 0.662199885742176 0.6172870166906905 1.0 17.704396194010585 -4.837023324214783 3.439490192933048 0.7345954773382358 0.9390426711691193 0.16328481744842327 0.12044682121569317 0.44159151905540633 8.655683754950378 0.029452492432366098 0.21732554760896233 1.4553809158111843e-05 4.837023324214783 0.2044471938308835 GLVAAYSGDS(ph)DNEEELVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLVAAYSGDSDNEEELVER 19 0 P52756 P52756 RBM5 RNA-binding protein 5 1 GLVAAYS(0.033)GDS(0.966)DNEEELVER 83.891 0.0013973 1201300.0 9046.6 8201.8 10507.0 10868.0 11327.0 8172.0 9443.6 10405.0 8103.3 7263.8 True False 10578.01070150539 9016.02050019214 10757.5267280194 10259.101194531393 9107.555661549848 7743.445934016193 8549.033842256767 10131.879775008787 8221.79543256253 8580.669439790841 1.2327721951917117 1.0507362582204205 1.2536931766808186 1.1956061548015378 1.0614038596237836 0.9024291156244499 0.9963131550800254 1.1807796403418795 0.9581764558410656 1.0 13.066874491803112 -6.377400810945619 4.459719416016423 1.0150769651073286 1.1782423576636132 0.4949436626391398 0.08345682234012951 0.21770905416844544 7.006344251546297 0.02709742604672362 0.030867984385478456 4.1937176658464123e-07 6.377400810945619 0.1631653925562846 GLVAAYSGDS(ph)DNEEELVER ddPTM_PC-9_Lapatinib_30min_R1 4 GLVAAYSGDSDNEEELVER 19 0 P52756 P52756 RBM5 RNA-binding protein 5 1 GLVAAYS(0.074)GDS(0.926)DNEEELVER;GLVAAY(0.039)S(0.102)GDS(0.858)DNEEELVER;GLVAAYSGDS(1)DNEEELVER;GLVAAYSGDS(1)DNEEELVER 180.02 6.602899999999999e-37 4084100.0 23736.5 19676.5 27192.6 22197.4 26850.5 22256.199999999997 22458.0 26448.0 24915.4 18658.300000000003 True False 23398.01315725901 19630.94027317055 24956.92939447151 23829.8708443557 25271.206380114094 21304.354207736185 23620.765352162067 27676.870633170933 22109.165281206584 21883.362294378025 1.0692147231538596 0.897071483307383 1.140452233013713 1.0889492448095028 1.1548136908836184 0.9735411734790594 1.079393789419206 1.2647448897869455 1.0103184777453769 1.0 14.417546799250092 -5.275033405721574 24.87563307276375 1.0963601175214244 0.9831430927458179 0.17837051560490058 0.08980352438737939 995.5947127274021 1821833.1371941497 0.022818214314415084 0.04793905663869973 5.308436104266899e-06 5.275033405721574 -0.11321702477560647 GLVGEIIK ddPTM_PC-9_AZD4547_30min_R2 1 GLVGEIIK 8 0 Q32Q12;P22392-2;J3KPD9;P22392;E7ERL0;E5RHP0;F6XY72;C9K028;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Nucleoside diphosphate kinase A 0 117.02 0.016425 1351800.0 17346.0 16099.0 20169.0 22449.0 22101.0 22738.0 16573.0 20633.0 14299.0 19355.0 False True 22861.667180786437 21302.686916896262 19901.54588180951 17273.729883592583 19032.657641029236 21316.18926550925 18047.964893844837 17444.643949171972 15054.81594801293 18677.387341203495 1.224029183693811 1.1405603218337284 1.0655422794549774 0.9248472266506806 1.0190214130775128 1.141283246746422 0.9663002947971148 0.933998081770676 0.8060450679202361 1.0 14.189005039441438 -1.5228787454177237 0.35391701808837284 0.9381305692089073 4.454156135886358 0.5481891799075138 0.07907954859409905 52.31765124412913 0.734183387059194 0.07153615410962046 123.21108851265777 0.0299999999905097 1.5228787454177237 3.516025566677451 GLVGEIIK ddPTM_PC-9_Lapatinib_30min_R1 1 GLVGEIIK 8 0 Q32Q12;P22392-2;J3KPD9;P22392;E7ERL0;E5RHP0;F6XY72;C9K028;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Nucleoside diphosphate kinase A 0 130.34 0.01781 20876000.0 89469.0 83390.0 101690.0 81385.0 88488.0 90741.0 107610.0 72000.0 87127.0 88268.0 False True 88193.15565339496 83196.91557846623 93329.44073475176 87370.32439240119 83283.30981410158 86860.21895760242 113181.51926022625 75345.38284892285 77313.8397720159 103525.00619028321 0.8519019597187207 0.803640768932164 0.9015159155190816 0.843953819542024 0.8044752942204461 0.8390264550957841 1.093277106906847 0.7277988731576113 0.7468131866605242 1.0 16.659619763410632 GLVGEIIKR ddPTM_PC-9_AZD4547_30min_R2 1 GLVGEIIKR 9 1 Q32Q12;P22392-2;J3KPD9;P22392;E7ERL0;E5RHP0;F6XY72;C9K028;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Nucleoside diphosphate kinase A 0 63.534 0.036124 3343700.0 32326.0 21681.0 40222.0 53955.0 42781.0 33791.0 31234.0 33277.0 29469.0 33207.0 False True 42604.99557743009 28688.959254936814 39688.62999941208 41516.508346440285 36841.596603813 31678.043428218098 34013.765491724465 28134.804279387183 31026.671177844142 32044.433037424136 1.329559974666191 0.895286841912025 1.238549920763473 1.2955919144505967 1.1497034932958976 0.9885662009130216 1.0614563051248365 0.8779935112763279 0.968239043006585 1.0 14.967786124009812 -6.748244032418839 4.077905020895233 0.974270911546958 1.1779882119179914 0.42790871460266733 0.11748657579792122 0.22318478154676918 8.341417869155118 0.04176020866989019 0.03942474744435109 1.7854840197970673e-07 6.748244032418839 0.20371730037103342 GLVGEIIKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLVGEIIKR 9 1 Q32Q12;P22392-2;J3KPD9;P22392;E7ERL0;E5RHP0;F6XY72;C9K028;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Nucleoside diphosphate kinase A 0 61.691 0.040996 5309000.0 26169.0 25770.0 32282.0 36392.0 37152.0 35947.0 33597.0 32245.0 31529.0 30820.0 False True 30598.894838690187 28328.275292003178 33051.72531016676 34353.0742244559 29872.33229786351 34061.87603892317 30414.448938783997 31398.60291640156 31990.0519779922 36407.42202901424 0.8404576081850824 0.7780906670466112 0.9078293234776904 0.9435733789961518 0.8205011679777078 0.9355750597166196 0.8353914461327624 0.8624231315081581 0.8786684196562531 1.0 15.151944968240945 -14.5228787452798 0.2663168512098032 1.8816806828411483 0.857785091461716 0.4039926037639603 0.04888378321215979 220.47314400508012 2.1482078292181366 106.79829593538572 0.06370526352035855 3.0000000000037193e-15 14.5228787452798 -1.0238955913794323 GLVGEIIKR ddPTM_PC-9_Lapatinib_30min_R1 1 GLVGEIIKR 9 1 Q32Q12;P22392-2;J3KPD9;P22392;E7ERL0;E5RHP0;F6XY72;C9K028;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Nucleoside diphosphate kinase A 0 101.25 0.0022513999999999998 7765600.0 69089.0 61948.0 68678.0 58871.0 63108.0 74268.0 53130.0 57309.0 54196.0 43930.0 False True 68103.77819062912 61804.56321207379 63031.55994474648 63200.5697278989 59396.11151510176 71091.7307671639 55880.81143291341 59971.78535679041 48091.87577081933 51523.24196695444 1.3218069281104043 1.1995472499908584 1.2233616818051385 1.2266419447835595 1.1528022936366613 1.3797992527869294 1.0845748306900755 1.1639753840655958 0.9334015860582707 1.0 15.652935753718117 -7.93573118818484 1.5293186921497965 0.9713049185486016 1.2378675499444658 0.6381515164820657 0.0776143955771594 0.2506943744380482 1.060367863301702 0.06312303875946819 0.021835190064864278 1.1594948174136546e-08 7.93573118818484 0.2665626313958642 GLVLDHGAR ddPTM_PC-9_AZD4547_30min_R2 2 GLVLDHGAR 9 0 P40227-2;P40227 P40227-2 CCT6A T-complex protein 1 subunit zeta 0 ; 120.87 0.0013857000000000001 12474400.0 29414.9 20630.8 37816.0 45533.0 40171.0 36749.0 34143.0 41683.0 31653.4 37303.0 False True 38768.22633207163 27299.30264271717 37314.53513146455 35036.07032783735 34593.95005193364 34451.079220608655 37181.660856244736 35241.85013005065 33326.53410230313 35997.03332414953 1.0769839276189177 0.758376458328935 1.0366002885696455 0.9733043835124185 0.9610222525956161 0.9570532913193228 1.0329090322924046 0.9790209602191786 0.9258133525116129 1.0 15.135590392079404 GLVLDHGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GLVLDHGAR 9 0 P40227-2;P40227 P40227-2 CCT6A T-complex protein 1 subunit zeta 0 ;; 149.57 0.00011779 12137900.0 108926.0 117447.0 135912.0 137814.0 159221.0 131914.0 143755.0 136401.0 128075.0 103652.0 False True 127365.02041343463 129106.36197981754 139152.65752913058 130092.72837901606 128022.78802751194 124996.19761867505 130137.48570392861 132820.61827880563 129947.85458090468 122443.28709121929 1.040196024127878 1.05441764139862 1.1364662027201453 1.0624733414915428 1.045568042714632 1.0208497385859452 1.0628388766382693 1.084752144720317 1.0612901504685557 1.0 16.901754155274737 -5.995084119429999 24.998901871248314 1.0501081320534227 1.078883058812194 0.15293525591781842 0.03207159127452504 285.0818710303418 1449713.2605377617 0.009352089833040046 0.013826191531651048 1.0113835382393223e-06 5.995084119429999 0.028774926758771358 GLVLDHGAR ddPTM_PC-9_Lapatinib_30min_R1 2 GLVLDHGAR 9 0 P40227-2;P40227 P40227-2 CCT6A T-complex protein 1 subunit zeta 0 ; 141.52 0.00059863 15352100.0 79226.0 69694.0 83697.0 66893.0 65742.0 69741.0 57730.0 59578.0 82426.0 57454.0 False True 78096.22271173095 69532.62782498663 76815.75573976318 71812.53436850659 61875.18481374494 66758.34000421147 60718.9769249406 62346.21138018212 73142.31589574051 67384.84734735715 1.158958219629979 1.0318733448568644 1.1399559213036625 1.0657074579144699 0.9182358831324369 0.9907025486024158 0.9010776059481868 0.9252259793481205 1.0854415907289159 1.0 16.040136592402963 -6.101796767618277 4.906059129495454 0.9644732173026497 1.102639919888008 0.5463035712318408 0.05830212634080069 0.16802546570715213 6.358993719964028 0.016936532120405114 0.02232628314251389 7.910487204414624e-07 6.101796767618277 0.13816670258535824 GLVLGPIHK ddPTM_PC-9_Lapatinib_30min_R1 2 GLVLGPIHK 9 0 F5GZS6;J3KPF3;P08195-2;P08195-3;P08195;P08195-4;F5H0E2;H0YFS2 F5GZS6 SLC3A2 4F2 cell-surface antigen heavy chain 0 ; 107.66 0.0020876 5953600.0 132325.0 114794.0 79802.0 69987.0 91978.0 93972.0 102588.0 66154.0 100076.0 89914.0 False True 130438.02123456691 114528.20154592254 73240.98760462839 75134.07744978779 86568.03487570555 89953.03661943131 107899.5046730608 69227.75634705032 88804.3870330008 105455.51509712602 1.2369008971643793 1.0860333045686652 0.6945202205609864 0.7124717695474555 0.820896230946055 0.8529950902670504 1.0231755501235174 0.6564640671783792 0.8421028236523307 1.0 16.68627502139595 -5.074842365598327 4.331358031442217 0.8178599781903524 1.2100837735108694 0.5907661802788617 0.11465809875655626 0.13457848892604124 4.648628499475249 0.029718245195966587 0.0940026362043516 8.417005954301438e-06 5.074842365598327 0.392223795320517 GLVSDGTS(ph)PGER ddPTM_PC-9_Lapatinib_30min_R1 2 GLVSDGTSPGER 12 0 Q9NRF2-2;Q9NRF2-3;Q9NRF2 Q9NRF2-2 SH2B1 SH2B adapter protein 1 1 GLVSDGT(0.057)S(0.942)PGER;GLVS(0.001)DGT(0.153)S(0.847)PGER 109.16 0.0013458 6363500.0 67789.0 73703.0 82845.0 70558.0 65816.0 72159.0 65674.0 55303.0 69460.0 57469.0 True False 66822.31642901983 73532.34523179886 76033.80389094807 75747.07069458789 61944.83227923464 69072.9277808447 69074.27837465004 57872.57927352736 61636.683353773544 67402.44007737105 0.9913931358021268 1.0909448552217293 1.128057141605988 1.1238030938885606 0.9190295219005181 1.0247837867821417 1.024803824540475 0.8586125251117853 0.9144577448979738 1.0 16.040513199796372 -6.701638226960898 1.0503639954528132 0.9352945888543376 1.0826795926680957 0.39915159255134314 0.06694508266610819 0.5068714667382078 1.1988571367218197 0.037679037458895615 0.036286903959757096 1.987750049931591e-07 6.701638226960898 0.14738500381375808 GLVSPQS(ph)PQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLVSPQSPQK 10 0 P41182-2;P41182 P41182-2 BCL6 B-cell lymphoma 6 protein 1 GLVS(0.216)PQS(0.784)PQK 88.021 0.010255 5083700.0 30586.0 45240.0 27632.0 27036.0 31357.0 25009.0 27823.0 19330.0 22681.0 25601.0 True False 35763.605698963576 49731.12821925587 28290.85167494356 25521.260571894632 25212.820948107943 23697.48401417166 25187.404018923902 18822.607981827965 23012.666716763633 30242.258642595512 1.182570591754393 1.644425067815892 0.9354741657786286 0.8438939985768303 0.8336950373341585 0.7835884314802568 0.8328545931899423 0.6223942531632463 0.7609440481522379 1.0 14.884278270787897 -5.413251971316351 4.852791699780603 0.8017604422796444 1.4082154284123745 0.7503684962259002 0.13664102189801414 0.09436947251844019 3.389417291891203 0.03467235664534736 0.07446739131818647 3.861428775920453e-06 5.413251971316351 0.6064549861327301 GLVSPQS(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 1 GLVSPQSPQK 10 0 P41182-2;P41182 P41182-2 BCL6 B-cell lymphoma 6 protein 1 GLVS(0.006)PQS(0.994)PQK 84.479 0.031532 0.0 21040.0 30252.0 26741.0 27617.0 28510.0 31961.0 28873.0 33417.0 28271.0 24769.0 True False 20739.965741736538 30181.953352677334 24542.458203245093 29648.046307611316 26833.09785281662 30594.10253472996 30367.902663326007 34969.675814756214 25086.82227317206 29050.288647382073 0.7139332071182557 1.0389553687067148 0.8448266556365797 1.0205766513195424 0.9236774952057056 1.0531428071537254 1.045356314077887 1.2037634544435956 0.8635653358794702 1.0 14.826264878052845 -3.6178940082880877 0.5690281473863725 1.0334075143750214 4.937740822547922e-15 0.35177089373429404 0.10502387018161019 14.734590268011479 1.31406534749193 0.049875793124888115 13.494773869760369 0.00024104936497775604 3.6178940082880877 -1.0334075143750165 GLVSPQS(ph)PQKSDCQPNSPTESCSSK ddPTM_PC-9_AZD4547_30min_R2 1 GLVSPQSPQKSDCQPNSPTESCSSK 25 1 P41182-2;P41182 P41182-2 BCL6 B-cell lymphoma 6 protein 1 GLVS(0.035)PQS(0.757)PQKS(0.208)DCQPNSPTESCSSK 93.40700000000001 0.00043432 0.0 3310.0 4665.1 5202.3 7307.4 7465.4 7234.0 3943.6 6531.7 3862.0 4965.7 True False 4362.511147722994 6173.002343997316 5133.3141028775635 5622.791828204574 6428.958072184047 6781.656836427742 4294.57276023451 5522.375848534218 4066.137435570737 4791.852354441445 0.9104018289878014 1.2882288283101457 1.071258820844016 1.1734067354961286 1.341643605989907 1.4152474523014047 0.8962239323283783 1.1524511692050925 0.848552320649433 1.0 12.22636774145392 -7.2833946013024295 24.998851660887702 0.9870111169617097 1.203413650452145 0.3454481963985224 0.15177228246592667 1015.5065674624265 1156280.0592695975 0.063600351516497 0.04291667695888355 5.207213670605286e-08 7.2833946013024295 0.21640253349043537 GLVSPQS(ph)PQKSDCQPNSPTESCSSK ddPTM_PC-9_Lapatinib_30min_R1 1 GLVSPQSPQKSDCQPNSPTESCSSK 25 1 P41182-2;P41182 P41182-2 BCL6 B-cell lymphoma 6 protein 1 GLVS(0.009)PQS(0.764)PQKS(0.227)DCQPNSPTESCSSK 104.23 0.00037841 0.0 6618.0 8857.1 6312.3 7094.9 5432.3 6067.9 4099.2 4956.1 7180.7 4089.7 True False 6523.626106407436 8836.591929128603 5793.327060182638 7616.682613892585 5112.782794312721 5808.3900619657625 4311.436518460359 5186.378499132579 6371.933949876786 4796.599195817289 1.3600523704578322 1.8422618960604946 1.207798864085728 1.5879339304677476 1.0659182861830836 1.210939214398145 0.8988527793233174 1.0812615954351958 1.3284274315505065 1.0 12.227796177533799 -6.266045782541882 24.925266583848135 1.0973625615890878 1.5031572874227734 0.5281819202288341 0.1860964460487836 292.8389958948447 1584550.9017438241 0.05522397060567919 0.06470893592103034 5.419437566557169e-07 6.266045782541882 0.4057947258336856 GLVSPQSPQKS(ph)DCQPNSPTESCSSK ddPTM_PC-9_Lapatinib_30min_R1 1 GLVSPQSPQKSDCQPNSPTESCSSK 25 1 P41182-2;P41182 P41182-2 BCL6 B-cell lymphoma 6 protein 1 GLVS(0.011)PQS(0.398)PQKS(0.591)DCQPNSPTESCSSK 71.634 0.0021353 0.0 5566.2 3784.6 4329.1 2879.4 3295.2 3044.9 2633.4 3523.1 3000.1 2273.5 True False 5486.824967283935 3775.836991225133 3973.178108809258 3091.1606813968206 3101.382814612462 2914.676725008579 2769.7445666748417 3686.796087708879 2662.1971455464454 2666.4714457516734 2.0577100032425846 1.4160425371293377 1.4900508742141156 1.1592701231891227 1.1631037037931558 1.0930837941851417 1.0387302557046718 1.3826497536970916 0.9983970200723364 1.0 11.380716163482534 -1.5228787452804065 0.6314728377770531 1.1147271196807644 72.66657700940743 0.8317782302721072 0.12688697967590568 75.11305622092028 0.5196396423390336 0.052512437645904526 7479.938369766713 0.029999999999995242 1.5228787452804065 71.55184988972667 up GLWGTTLTENTAENR ddPTM_PC-9_Lapatinib_30min_R1 1 GLWGTTLTENTAENR 15 0 Q9P0L9-4;Q9P0L9-3;Q9P0L9-2;Q9P0L9-5;Q9P0L9 Q9P0L9-4 PKD2L1 Polycystic kidney disease 2-like 1 protein 0 61.532 0.039139 51550000.0 64964.0 66414.0 71971.0 56249.0 76020.0 66238.0 56970.0 58453.0 75974.0 22472.0 False True 64037.60144706143 66260.22246346396 66053.82219609407 60385.73910116337 71548.65306107051 63405.155148319536 59919.62784364912 61168.93977316777 67417.00807831263 26356.255257942175 2.4296927169789946 2.5140226414940776 2.506191473319771 2.291135007996509 2.7146744619385976 2.4056966563644533 2.273449974483495 2.3208509393509216 2.5579130046555925 1.0 14.68585778386439 -11.259183026557723 0.6087349202508603 2.3485932225427677e-22 2.453297348008794 0.9176354646795966 0.12981398678388434 25.322475037167447 3.055244689635746 37.45754166754924 0.052103780926349826 5.505756160983333e-12 11.259183026557723 2.453297348008794 GLWSTDS(ph)AEEDKETK ddPTM_PC-9_Lapatinib_30min_R1 1 GLWSTDSAEEDKETK 15 1 Q99549-2;Q99549;A0A0A0MT47 Q99549-2 MPHOSPH8 M-phase phosphoprotein 8 1 GLWS(0.044)T(0.31)DS(0.647)AEEDKETK 178.47 0.00018032 3406600.0 33756.0 33544.0 32523.0 32014.0 33888.0 28123.0 30997.0 36590.0 29640.0 31797.0 True False 33274.63324990774 33466.330928937205 29849.08448241053 34368.416355573325 31894.77446637143 26920.244847914968 32601.87299051416 38290.10497836222 26301.63107696296 37293.06908316072 0.892247113685061 0.8973874167961297 0.800392277070287 0.921576507391611 0.8552467053663108 0.7218565140853616 0.8742072935272356 1.0267351526627693 0.7052686122000931 1.0 15.186619910070958 -11.489999126302454 2.3417528402486556 1.1185986438164148 0.8582986665046395 0.18914929099968447 0.0898362844995071 25801572.746511184 10989256.360939689 16604754.683207002 0.02290267998763585 3.2359430792401147e-12 11.489999126302454 -0.26029997731177534 GLYDGPVCEVS(ph)VTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GLYDGPVCEVSVTPK 15 0 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 1 GLYDGPVCEVS(0.934)VT(0.066)PK 133.47 3.7813e-06 6308200.0 25875.0 30757.0 27348.0 35345.0 33835.0 21453.0 27681.0 23783.0 19139.0 18850.0 True False 30255.126445454895 33810.35169406833 28000.08003786755 33364.73424003607 27205.27463657978 20327.966914151886 25058.85528691488 23158.721450171466 19418.871667569314 22267.3557834821 1.3587211135279076 1.518381976864483 1.2574497084489025 1.498369836295785 1.2217559597606387 0.9129043929513692 1.1253628643910882 1.0400301533489926 0.872078025625935 1.0 14.442642629882187 -6.54389688179322 4.190463471730982 1.0026816902131244 1.4031694544291968 0.8145420071928757 0.09402298907713268 0.08631088300555113 3.5251077125378925 0.03044960911159358 0.031648901757310756 2.858269125789739e-07 6.54389688179322 0.40048776421607246 GLYDGPVCEVS(ph)VTPK ddPTM_PC-9_Lapatinib_30min_R1 1 GLYDGPVCEVSVTPK 15 0 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 1 GLYDGPVCEVS(0.85)VT(0.15)PK 201.57 2.2721e-10 94477000.0 311930.0 308680.0 239830.0 245020.0 233390.0 221880.0 194830.0 177320.0 198650.0 153200.0 True False 307481.8209990434 307965.270425243 220112.103170572 263039.5881627589 219662.45906239457 212390.70962754247 204917.34408948873 185558.93453848572 176275.94512276317 179680.41587383166 1.7112706440692544 1.7139612513001454 1.2250200006501026 1.4639302056572518 1.2225175347804047 1.1820470728244494 1.1404545291868535 1.0327165241468599 0.9810526331736729 1.0 17.455073646437675 -3.2930072890288717 0.2806631731611022 0.949876200894815 3.525169822394095 0.8679447491841517 0.09412164584616602 6.300023357630092 0.21076561202365346 0.10570749228085981 6.50398469756711 0.0005093223227186269 3.2930072890288717 2.57529362149928 GLYDGPVCEVSVT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 GLYDGPVCEVSVTPK 15 0 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 1 GLYDGPVCEVS(0.353)VT(0.647)PK;GLYDGPVCEVSVT(1)PK;GLYDGPVCEVS(0.001)VT(0.999)PK;GLYDGPVCEVS(0.406)VT(0.594)PK 203.92 2.2686e-12 180289700.0 569803.0 573526.0 561441.0 720934.0 698296.0 657396.0 643291.0 651550.0 611954.0 664217.0 True False 750988.5013613326 758907.0635877915 553995.9255009671 554733.8046192676 601349.6538663489 616288.9241968837 700542.6527802066 550867.9186295255 644300.639111148 640962.9650019205 1.1716566203775634 1.1840107853743431 0.8643181521405174 0.8654693561235718 0.9381971918838511 0.9615047324848748 1.09295340141549 0.8594379842646211 1.0052072807501717 1.0 19.28988147441399 -5.249602344371848 24.64818949529005 0.9456723921893908 1.17783375619264 0.6317887597868646 0.07004131877662349 390.8776113451435 813917.5576616171 0.018311738824223416 0.04757769249351809 5.628564609102477e-06 5.249602344371848 0.23216136400324916 GLYDGPVCEVSVT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GLYDGPVCEVSVTPK 15 0 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 1 GLYDGPVCEVS(0.001)VT(0.999)PK;GLYDGPVCEVS(0.03)VT(0.97)PK;GLYDGPVCEVS(0.001)VT(0.999)PK;GLYDGPVCEVS(0.26)VT(0.74)PK 215.15 2.7163999999999998e-17 157604000.0 563259.0 569527.0 440907.0 619776.0 570114.0 455735.0 495729.0 442870.0 373818.0 364297.0 True False 658607.6238276521 626065.8766871837 451419.89502910816 585051.9600609031 458404.25429759215 431835.4543243839 448769.9603528429 431245.13175955234 379284.38105582516 430341.1623265341 1.5304313913803904 1.4548129054225534 1.048981446693635 1.3595073194903387 1.065211265915958 1.0034723427100751 1.0428236934777004 1.0021005878873663 0.8813574304752003 1.0 18.715121315755304 -2.506927326979169 0.33197990690473284 0.9386081561021518 4.384349628590561 0.7752472360220141 0.10025299567853689 13.587359653071227 0.3530350095916299 0.08989396477317023 25.54851996718592 0.003112237082261998 2.506927326979169 3.4457414724884092 GLYDGPVCEVSVT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 GLYDGPVCEVSVTPK 15 0 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 1 GLYDGPVCEVS(0.098)VT(0.902)PK;GLYDGPVCEVS(0.071)VT(0.929)PK 179.74 6.695300000000001e-05 101119000.0 443715.0 445585.0 396953.0 413598.0 384684.0 314017.0 322900.0 269226.0 258458.0 265729.0 True False 437387.54273263545 444553.2753091607 364317.05662289134 444015.37664248206 362057.6434378428 300587.2249193795 339618.1820381658 281735.22281783447 229347.73835660264 311659.9035883636 1.4034129437142202 1.4264050979631981 1.1689570985174809 1.4246791824364158 1.1617074871332946 0.9644719178133073 1.0897076528866836 0.9039828979410413 0.7358910649588154 1.0 18.249613032302904 -6.701583283249193 0.8555436026333788 0.8771668332863521 1.3859485368343216 0.7660885910425048 0.10860523254732823 0.2850892454791248 0.4572388779692691 0.06797920165981958 0.06804505727330329 1.988001541210026e-07 6.701583283249193 0.5087817035479695 GMDDDRGPR ddPTM_PC-9_Lapatinib_30min_R1 1 GMDDDRGPR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 115.49 0.0025607 8558300.0 18630.0 20406.0 21652.0 23985.0 29010.0 22736.0 20612.0 22825.0 25675.0 20197.0 False True 18364.332783676422 20358.751160740896 19871.856139137002 25748.936911614474 27303.688835854424 21763.634280204624 21679.188504709437 23885.532826759172 22783.21113026398 23688.02453918915 0.7752580952157794 0.8594533126668984 0.8388988328790892 1.0870022896597298 1.152636801379683 0.9187610492465996 0.9151961350277933 1.0083378961062484 0.9618029182877508 1.0 14.531870269712684 -5.699998746496919 8.767655440257569 1.0051478582035271 0.8269527951033453 0.5821446521559923 0.07054776986609002 0.24010336511274097 31.3390366641425 0.021103676219107675 0.0365466783359535 1.9952680738978375e-06 5.699998746496919 -0.17819506310018185 GMDGSTNETAS(ph)SR ddPTM_PC-9_AZD4547_30min_R2 2 GMDGSTNETASSR 13 0 Q9Y3B9 Q9Y3B9 RRP15 RRP15-like protein 1 GMDGSTNETAS(0.879)S(0.121)R;GMDGSTNETAS(0.909)S(0.091)R 113.65 0.00028261 8264400.0 23613.2 21571.7 24959.0 33169.0 31616.0 30992.0 24230.1 35773.0 28975.0 27885.0 True False 31121.706414928296 28544.33016741484 24628.02735207911 25522.399505941565 27226.66413188454 29054.065340692345 26386.531960076627 30245.104831761197 30506.559346365128 26908.75463753342 1.1565643536515986 1.0607822826404627 0.9152421835876023 0.948479401954258 1.0118143518209382 1.0797253805334623 0.9805928336524212 1.1239875363675917 1.1337038728582907 1.0 14.715788002789765 -7.766055658544609 24.999736773466545 1.0966342853862552 1.0182940746179834 0.13328894936744762 0.0728803300861703 212.37434497789397 1150095.132183705 0.04012604543206268 0.020282619491513342 1.713737663325586e-08 7.766055658544609 -0.0783402107682718 GMDGSTNETAS(ph)SR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GMDGSTNETASSR 13 0 Q9Y3B9 Q9Y3B9 RRP15 RRP15-like protein 1 GMDGSTNET(0.001)AS(0.978)S(0.021)R;GMDGSTNETAS(0.961)S(0.038)R 113.37 0.00031036 9445300.0 33285.0 32280.0 34880.0 28869.0 29820.0 23778.6 28035.0 25657.0 22804.7 15307.5 True False 38919.49309128367 35484.54506891201 35711.671483136626 27251.56352456082 23976.985064661123 22531.608356167068 25379.321844176822 24983.530935838604 23138.175595246248 18082.62857589668 2.1523139143145142 1.9623554683975146 1.9749159439540032 1.5070576387818921 1.3259679014046304 1.2460361203348873 1.4035195014737127 1.3816315936025203 1.2795803164418464 1.0 14.142316789480036 -5.834914948358317 2.0135385055730195 1.2934971900150056 2.0641712724090966 0.8993015269888407 0.11335947439401366 0.09246477731871462 0.7653641324899786 0.03389517199237666 0.06217631201761967 1.4624635532904345e-06 5.834914948358317 0.770674082394091 GMDGSTNETAS(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 4 GMDGSTNETASSR 13 0 Q9Y3B9 Q9Y3B9 RRP15 RRP15-like protein 1 GMDGSTNETAS(0.986)S(0.014)R;GMDGSTNET(0.001)AS(0.996)S(0.002)R;GMDGSTNET(0.003)AS(0.511)S(0.486)R;GMDGST(0.001)NET(0.011)AS(0.851)S(0.137)R 138.01 5.4772e-05 11868600.0 73927.0 64107.1 74810.0 65660.0 55386.9 52988.3 45237.100000000006 39173.0 61549.6 34825.0 True False 72872.7874234487 63958.663948678506 68659.41057495109 70488.85543533895 52129.15143683507 50722.113930760315 47579.25569116973 40993.120588067344 54617.2359019784 40844.45484860432 1.784153753393499 1.5659081308772569 1.680997110365331 1.7257876423278444 1.276284666549206 1.241835987743475 1.1648889884203104 1.0036398022697102 1.3372007560004122 1.0 15.31785260711397 -6.3929059734860205 2.7877566408534276 1.1525613168979245 1.6832978796226443 0.8472813012955089 0.10858340086849882 0.10216200284600195 1.5356329432651985 0.03538538554605612 0.0408203599497987 4.046634934990293e-07 6.3929059734860205 0.5307365627247198 GMGPGT(ph)PAGYGR ddPTM_PC-9_AZD4547_30min_R2 2 GMGPGTPAGYGR 12 0 P23246 P23246 SFPQ Splicing factor, proline- and glutamine-rich 1 GMGPGT(1)PAGYGR;GMGPGT(0.991)PAGY(0.009)GR 89.35600000000001 0.028787 39799300.0 69163.0 68315.0 86619.0 139035.0 104512.0 88794.0 78539.0 100579.0 95714.0 98395.0 True False 91155.39532023134 90396.48777736316 85470.37546415075 106982.62881933694 90002.31280843593 83241.69714318015 85528.81884979656 85036.82662549162 100773.24663599623 94950.22099910725 0.9600335245253239 0.9520408359893454 0.9001598370682505 1.1267233261136151 0.9478894505077788 0.8766877661502528 0.9007753531253048 0.8955937725125587 1.0613271414812582 1.0 16.534883737838335 -6.505403205620146 24.963225063457113 0.9346721249571659 0.9839803686798035 0.04592179611408209 0.0743925652300452 1983.9642561552605 2834030.9314023294 0.023670002381543848 0.026243942605943805 3.123178414218515e-07 6.505403205620146 0.049308243722637646 GMGPGT(ph)PAGYGR ddPTM_PC-9_Lapatinib_30min_R1 3 GMGPGTPAGYGR 12 0 P23246 P23246 SFPQ Splicing factor, proline- and glutamine-rich 1 GMGPGT(1)PAGYGR;GMGPGT(1)PAGYGR;GMGPGT(0.999)PAGY(0.001)GR 130.69 0.00033908 51186500.0 120080.0 117115.0 112351.0 99090.0 94228.0 88085.0 75471.0 79723.0 102783.0 78109.0 True False 118367.63718002482 116843.82741302402 103113.93446740192 106377.4091545501 88685.69429937581 84317.80988616392 79378.5190975609 83427.22162312035 91206.49618702714 91610.03657629949 1.2920815404482417 1.2754478851856803 1.1255746457597051 1.161198195417718 0.9680783636137065 0.9203992601393398 0.8664827792252731 0.9106777460309832 0.9955950198869721 1.0 16.483218044745513 -5.9406808746127995 1.1204822266018537 0.9239159833043625 1.2853971806390905 0.8738357226424681 0.0514163173563136 0.16925449580501034 0.42890045298976714 0.020374980205490962 0.04418001285401324 1.1463549889942394e-06 5.9406808746127995 0.36148119733472794 GMKDDKEEEEDGT(ph)GSPQLNNR ddPTM_PC-9_AZD4547_30min_R2 1 GMKDDKEEEEDGTGSPQLNNR 21 2 P49407-2;P49407 P49407-2 ARRB1 Beta-arrestin-1 1 GMKDDKEEEEDGT(0.764)GS(0.236)PQLNNR 52.653999999999996 0.014288999999999998 8367600.0 26512.0 22924.0 19391.0 26298.0 26352.0 24210.0 28151.0 24465.0 28560.0 23357.0 True False 34942.264516142626 30333.734696747015 19133.862670145667 20235.402400049774 22693.479668630484 22696.144872811117 30656.384464286853 20684.496399771837 30069.623293604414 22539.27853931748 1.5502831847607454 1.345816577217984 0.848911939961547 0.8977839448033428 1.006841440334659 1.0069596874283264 1.3601315770072189 0.9177088948827636 1.3340987485979647 1.0 14.460153716514466 -5.045483051529501 4.788545810906952 1.0473560848095178 1.5130434189790207 0.508868475467237 0.16329600688965787 0.14378939141451516 7.532568099723065 0.04213170519195269 0.13358617658856806 9.005689070326197e-06 5.045483051529501 0.4656873341695029 GMKDDKEEEEDGT(ph)GSPQLNNR ddPTM_PC-9_Lapatinib_30min_R1 1 GMKDDKEEEEDGTGSPQLNNR 21 2 P49407-2;P49407 P49407-2 ARRB1 Beta-arrestin-1 1 GMKDDKEEEEDGT(0.94)GS(0.06)PQLNNR 60.17100000000001 0.0052071 15186000.0 19485.0 25538.0 21969.0 21491.0 19461.0 20710.0 16609.0 24626.0 19187.0 19216.0 True False 19207.14032688863 25478.86833005005 20162.793622792404 23071.519831874382 18316.34224179811 19824.281577367947 17468.932751538865 25770.2138616329 17025.958011932817 22537.45999628949 0.8522318100642595 1.1305119713687712 0.8946346937992105 1.0236965405894372 0.8127065891548411 0.8796147205866041 0.775106545032799 1.1434391393651122 0.7554515022871223 1.0 14.460037310443628 -6.24426841120236 24.86310684126282 0.8948557879253414 0.9805979764915121 0.08786239682789343 0.12720159732370087 1905.3891981808442 2758951.3350917134 0.03564360533325595 0.045894723965053466 5.69811997034205e-07 6.24426841120236 0.08574218856617077 GMKDDKEEEEDGTGS(ph)PQLNNR ddPTM_PC-9_AZD4547_30min_R2 1 GMKDDKEEEEDGTGSPQLNNR 21 2 P49407-2;P49407 P49407-2 ARRB1 Beta-arrestin-1 1 GMKDDKEEEEDGT(0.281)GS(0.719)PQLNNR 71.634 0.0061278 12170000.0 28936.0 28760.0 25627.0 22331.0 25203.0 30430.0 24193.0 27957.0 27383.0 23547.0 True False 38137.046093810466 38056.10756754686 25287.169235615656 17182.932960510756 21703.998485446806 28527.20728953501 26346.130131948838 23636.88803794896 28830.409476497538 22722.62669714899 1.6783731301009988 1.6748111067776228 1.1128629437365374 0.7562036374371587 0.9551711945419589 1.255453767284498 1.1594667501734952 1.040235724196212 1.2687973912855284 1.0 14.47184199713461 -5.274407262471165 5.44451038294498 1.062540569798029 1.682766375472535 0.7481072716836715 0.1413135532049485 0.07996692668142973 8.47387542178033 0.04001883591366314 0.09384187487041235 5.316095051820933e-06 5.274407262471165 0.620225805674506 GMLPHK ddPTM_PC-9_Lapatinib_30min_R1 1 GMLPHK 6 0 P40429;Q8J015 P40429 RPL13A;RPL13a 60S ribosomal protein L13a 0 78.002 0.026488 0.0 52888.0 46949.0 48996.0 52837.0 51661.0 47516.0 54904.0 44417.0 55286.0 51777.0 False True 52133.80742152864 46840.29247503795 44967.73801002938 56722.80923906499 48622.40154943384 45483.851445206 57746.66047266481 46480.775972230505 49059.1084926105 60726.585461484174 0.8585005566399662 0.7713309108207047 0.740495084126707 0.9340688070637764 0.8006773504542354 0.7489940542442342 0.9509288235758063 0.7654106618873036 0.8078687138391181 1.0 15.890040631064544 -11.458297626864812 2.295680187278675 1.1286308767058102 0.8190214837297218 0.3741384833438608 0.0699097063905028 16306343.593220718 7496491.873290361 11231099.680743936 0.017102935976477048 3.4809867735871705e-12 11.458297626864812 -0.30960939297608836 GMLTSSGGQS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 2 GMLTSSGGQSPSR 13 0 O43365 O43365 HOXA3 Homeobox protein Hox-A3 1 GMLTS(0.002)S(0.002)GGQS(0.742)PS(0.253)R;GMLTSSGGQS(0.932)PS(0.068)R 103.11 0.0013920999999999998 9992900.0 35067.0 41604.0 45288.0 44106.0 38540.0 47171.0 38412.0 53390.0 38576.0 40954.0 True False 46217.57656108831 55051.67938943737 44687.451529346494 33938.04313090714 33189.386248824325 44221.389913067884 41830.59358609593 45139.80228014788 40615.04860553516 39520.212925427455 1.1694667902801643 1.3930005765231317 1.1307492602246183 0.8587515253256968 0.839807880373796 1.118956266670711 1.0584607341318741 1.1421953207925344 1.0277031827276235 1.0 15.270303099387798 -5.519439009952583 24.739068557946762 1.011020973464289 1.2763940279012358 0.5255240179495759 0.10442100132627133 94.49739625561354 679637.5939600476 0.03032787932898447 0.05400546202134 3.0238551951155533e-06 5.519439009952583 0.2653730544369468 GMLTSSGGQS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 1 GMLTSSGGQSPSR 13 0 O43365 O43365 HOXA3 Homeobox protein Hox-A3 1 GMLTSSGGQS(0.642)PS(0.357)R 72.815 0.020007 4656100.0 10512.0 16802.0 18410.0 14291.0 17048.0 18835.0 19030.0 16332.0 16780.0 16555.0 True False 10362.096952335296 16763.096001311813 16896.40086465511 15342.00781337847 16045.270157657578 18029.47095652948 20015.280285494868 17090.844342897282 14890.059698766485 19416.5096918491 0.5336745438179975 0.8633423961026749 0.8702079381315421 0.7901527131737238 0.8263725258712825 0.9285639511254751 1.0308382198010144 0.8802222754830075 0.7668762272457864 1.0 14.244996265022355 -4.7600914522134605 5.095259028258532 0.882493818191306 0.5120409751880706 0.6370872085390802 0.07945957152071369 0.11682712658549577 8.250969900546586 0.020843113838155465 0.15511646748946456 1.7374349272536708e-05 4.7600914522134605 -0.37045284300323544 GMLTSSGGQSPS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 GMLTSSGGQSPSR 13 0 O43365 O43365 HOXA3 Homeobox protein Hox-A3 1 GMLT(0.001)S(0.005)S(0.005)GGQS(0.311)PS(0.678)R 63.727 0.039014 2327300.0 9506.4 14660.0 16270.0 17313.0 12970.0 12986.0 13212.0 17742.0 11727.0 12802.0 True False 12529.23745459634 19398.558308074997 16054.249169370842 13321.755333183582 11169.339378496403 12173.983367134451 14387.842404964582 15000.381570600939 12346.865278855 12353.805876625534 1.0142006098948613 1.5702495653407296 1.2995387275549526 1.0783523285232683 0.9041213282806844 0.9854439586240121 1.1646485745892785 1.214231607684799 0.9994381814122831 1.0 13.59266794552744 -5.761516976003379 5.158170216420767 1.0530682628303871 1.3254884696875975 0.35305201667611685 0.1509728385906402 0.17932277446779546 13.683732790098825 0.042294058629748645 0.0692304182805264 1.7317413379227772e-06 5.761516976003379 0.27242020685721036 GMLTSSGGQSPS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GMLTSSGGQSPSR 13 0 O43365 O43365 HOXA3 Homeobox protein Hox-A3 1 GMLT(0.001)S(0.009)S(0.009)GGQS(0.347)PS(0.635)R;GMLTS(0.001)SGGQS(0.369)PS(0.629)R 82.515 0.0091816 5699800.0 26997.0 38549.0 33336.0 31114.0 36950.0 25821.0 31345.0 23694.1 22768.5 21255.8 True False 31567.05888494475 42375.88995853436 34130.856667484 29370.783452949014 29709.912747794395 24466.901304727347 28375.774681852086 23072.154980974115 23101.44623872991 25109.308279179768 1.257185523948489 1.6876566047688284 1.3592909963109079 1.1697169482483432 1.1832230668189843 0.9744155845589305 1.1300898601567937 0.9188686014144473 0.9200351511827689 1.0 14.615934664791967 -6.051873249589994 1.0442677067867665 0.9833113336148585 1.49358229305039 0.7086724154844353 0.12127889484691565 0.28195930572013067 0.630026987786485 0.04947283665730399 0.09692340113415704 8.87414969504924e-07 6.051873249589994 0.5102709594355315 GMLTSSGGQSPS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 GMLTSSGGQSPSR 13 0 O43365 O43365 HOXA3 Homeobox protein Hox-A3 1 GMLTSSGGQS(0.111)PS(0.889)R 93.348 0.01765 0.0 17258.0 22836.0 23002.0 15516.0 22992.0 21355.0 20451.0 20151.0 19971.0 15976.0 True False 17011.897755270413 22783.124645039657 21110.864350287717 16657.098399858678 21639.6557640112 20441.696430936387 21509.85271248849 21087.289024842237 17721.655676046805 18737.430313318095 0.9079098612139351 1.2159151102403827 1.1266680647923555 0.8889745349990298 1.1548891924967042 1.0909551677642233 1.1479617190197007 1.125409870629588 0.9457890105374106 1.0 14.193635492181965 -8.264996988358554 24.947185518166414 0.9728944958560465 1.0867138121909692 0.15874320899464345 0.10037179637521626 561.836719260776 3939689.544608736 0.0829025016309254 0.02466507477677737 5.432540987078935e-09 8.264996988358554 0.1138193163349227 GMQAASS(ph)KMVSAEIS(ph)ENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GMQAASSKMVSAEISENR 18 1 Q6IQ49-3;Q6IQ49-2;Q6IQ49 Q6IQ49-3 SDE2 Protein SDE2 homolog 2 GMQAAS(0.429)S(0.571)KMVSAEIS(1)ENR 87.669 0.017731999999999998 0.0 2122.8 3785.0 6175.8 6960.8 8322.9 9434.3 7236.4 7586.4 12814.0 1929.2 True False 2482.148112788854 4160.749785806443 6323.054493851922 6570.808943218083 6692.087491437557 8939.54869986404 6550.915805000934 7387.265038455231 13001.380508293701 2278.9486884612033 1.0891636680353938 1.8257321048399178 2.7745488636347444 2.883263224173265 2.9364801082714167 3.9226634391229855 2.874534138556782 3.2415231970155833 5.704990452010801 1.0 11.154152726713331 -4.917151425566603 0.785768065560116 3.436119748404473 4.3600183853135206e-17 0.30147598768732853 1.0908676918169524 2.615117977319486 1.4109094173571417 0.4151835983370879 7.617736463884632 1.2101761075719809e-05 4.917151425566603 -3.436119748404473 GMS(ph)S(ph)GEGLPSRS(ph)SQVS(ph)AGK ddPTM_PC-9_Lapatinib_30min_R1 1 GMSSGEGLPSRSSQVSAGK 19 1 Q5JWM4;Q9H6P5-2;Q9H6P5-3;Q9H6P5 Q5JWM4 TASP1 Threonine aspartase 1;Threonine aspartase subunit alpha;Threonine aspartase subunit beta 4 GMS(0.997)S(0.997)GEGLPS(0.011)RS(0.521)S(0.521)QVS(0.953)AGK 52.172 0.022894 2013500.0 3960.5 4169.1 4388.3 3606.0 4828.1 3848.3 3131.0 3308.8 3897.1 2359.7 True False 3904.0225437332506 4159.4467050987405 4027.5109133278643 3871.1972692633663 4544.120650409818 3683.717179825453 3293.107859899342 3462.5389273682686 3458.167559717693 2767.5710008973915 1.4106313957139174 1.502923214526395 1.4552511614054109 1.3987707155509728 1.6419165574926085 1.3310289703971456 1.1898910123106305 1.2511111462887607 1.2495316501713503 1.0 11.434404613892445 -7.888229371101246 0.576887295838992 1.026583454545705 1.4888068644625545 0.7200831972683626 0.09065912284505254 0.43309694414410055 0.3186236129100883 0.0938926992607722 0.05231389249279079 1.2935124969427272e-08 7.888229371101246 0.4622234099168494 GMSNCS(ph)MTPMTSAPRTGS(ph)IRPPDSLMT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 GMSNCSMTPMTSAPRTGSIRPPDSLMTPK 29 2 H0YIT5;Q6X4T0 H0YIT5 C12orf54 Uncharacterized protein C12orf54 3 GMS(0.204)NCS(0.505)MT(0.155)PMT(0.247)S(0.264)APRT(0.188)GS(0.282)IRPPDS(0.286)LMT(0.868)PK 40.756 0.031711 60322000.0 3373.5 4634.1 5531.2 5324.3 6631.2 5658.1 5096.2 4265.9 5290.8 5503.2 True False 3325.3932713758663 4623.370026168253 5076.446087049445 5715.866783344131 6241.165853440809 5416.116252675308 5360.056300101893 4464.109287433601 4694.894389406059 6454.420787446933 0.5152117255576757 0.7163105998852985 0.7865068383707672 0.8855739301132645 0.9669598650244683 0.8391328100592695 0.8304472975369925 0.6916359243444048 0.7273920532942415 1.0 12.65607192015258 -4.774955561342244 1.624428495524103 0.8379048055678645 0.39455769603873014 0.5606670013856847 0.08961471967033142 0.8527631846722317 2.158354196494482 0.0269474603409224 0.6070940583880569 1.678975808502847e-05 4.774955561342244 -0.44334710952913436 GMSNNT(ph)PQLNR ddPTM_PC-9_AZD4547_30min_R2 1 GMSNNTPQLNR 11 0 F8VQD8;A0A087X050;F8VVY1;F8VX63;F8VUB4;F8VV52;F8VP97;Q9NZN8-4;Q9NZN8-5;Q9NZN8;F8VWH8;F8W145 F8VQD8 CNOT2 CCR4-NOT transcription complex subunit 2 1 GMS(0.001)NNT(0.999)PQLNR 93.839 0.026294 6066300.0 10054.0 10450.0 12972.0 16148.0 13643.0 16377.0 12250.0 15334.0 9258.8 10887.0 True False 13250.96286380876 13827.758139112115 12799.982804245765 12425.328084113007 11748.904945322016 15352.943601075074 13340.22626860551 12964.482640265745 9748.201265785174 10505.8494437449 1.26129380920248 1.3161961070501589 1.2183672412959214 1.1827057060589183 1.1183203231907364 1.4613709898742262 1.2697903525114929 1.2340251694721074 0.9278832062065362 1.0 13.358905194462256 -8.22913170258661 6.401321244475518 0.9633289859040051 1.2592128511095941 0.6490667004423797 0.08644665525169293 0.10869138279817306 15.175372237989226 0.06517657218402793 0.022992333155170158 5.900221250455533e-09 8.22913170258661 0.29588386520558907 GMWSEGNGSHTIR ddPTM_PC-9_AZD4547_30min_R2 1 GMWSEGNGSHTIR 13 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 99.669 0.0016614000000000002 1328100.0 9003.4 6796.3 12472.0 21758.0 13669.0 12614.0 12535.0 12249.0 10355.0 14945.0 False True 11866.293917646293 8993.071066109827 12306.613130939972 16742.029257749004 11771.29529411468 11825.244585941327 13650.590716487352 10356.198504018192 10902.344159848513 14421.780098903975 0.8228036924892584 0.6235756615643642 0.8533352364646891 1.1608850740292014 0.8162165289851614 0.8199573495674103 0.9465260614759178 0.718094329063112 0.7559638328334426 1.0 13.815961628827223 -5.496519588034415 23.66173193175722 0.88338242775954 0.7270059902443385 0.20207813143594078 0.12905780889692497 615.3379360030406 552365.3934817351 0.03493136181623565 0.07224812544200943 3.187721796267378e-06 5.496519588034415 -0.15637643751520147 GMWSEGNGSHTIR ddPTM_PC-9_Lapatinib_30min_R1 2 GMWSEGNGSHTIR 13 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 ; 99.161 0.0018893 1191400.0 22457.1 17538.8 18511.8 14195.5 22434.0 16028.900000000001 16234.3 17821.5 22114.0 12952.8 False True 22136.857635872235 17498.189986180652 16989.831261614454 15239.48442479981 21114.47622694101 15343.381312190888 17074.83261896003 18649.55195058437 19623.28844925639 15191.67422147888 1.4571703759006265 1.1518276215692334 1.1183646393360145 1.0031471319502978 1.3898715782812223 1.0099861995788137 1.1239598986936299 1.2276166325510416 1.291713353193938 1.0 13.890993252544424 -4.761459903364473 10.207474865593296 1.1506296703106986 1.4582952038079908 0.3680984724182197 0.12208258903404282 0.0780979629035617 191.40192784154354 0.02940077542881448 0.16596751627501066 1.7319689289851662e-05 4.761459903364473 0.3076655334972922 GNAEGS(ph)SDEEGKLVIDEPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GNAEGSSDEEGKLVIDEPAK 20 1 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 GNAEGS(0.645)S(0.355)DEEGKLVIDEPAK 92.679 0.00029614 5173300.0 11956.0 28939.0 22088.0 13095.0 13835.0 11685.0 14242.0 10270.0 10278.0 9919.0 True False 13979.914658236074 31811.87266881178 22614.661689206463 12361.329604562814 11124.131065378491 11072.218029733127 12892.894656849165 10000.42338196446 10428.296305934344 11717.236181239208 1.1931068420912863 2.7149638512661074 1.9300337843676332 1.0549697397373352 0.9493818246311059 0.9449513399295614 1.1003358178861613 0.8534797137550589 0.8899962537779497 1.0 13.516344691814421 -5.759855018562177 4.633461121994905 0.9606101239431382 2.0400853743800202 0.62151416746349 0.34819441722744443 0.10790615159013288 5.823561794323578 0.09230153336840137 0.15270370451208626 1.7383810592894622e-06 5.759855018562177 1.079475250436882 GNAEGS(ph)SDEEGKLVIDEPAK ddPTM_PC-9_Lapatinib_30min_R1 2 GNAEGSSDEEGKLVIDEPAK 20 1 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 GNAEGS(0.5)S(0.5)DEEGKLVIDEPAK;GNAEGS(0.5)S(0.5)DEEGKLVIDEPAK 74.812 0.0011530999999999998 50724100.0 43484.0 90428.0 63264.0 67382.0 90148.0 75000.0 90498.0 106252.0 65470.0 90651.0 True False 42863.91018601103 90218.61952187966 58062.67812610212 72337.49705976246 84845.67187778713 71792.42483353912 95183.54362988521 111188.85581199617 58096.07917033622 106319.90456513508 0.4031597880127064 0.8485581311503978 0.5461129631707956 0.6803758652308245 0.7980224608441768 0.6752491466878313 0.8952561048582642 1.0457952936167114 0.5464271192488199 1.0 16.6980521891723 -3.786800773486595 0.17246660333707903 0.9948676807738964 1.302204365035459e-10 0.33678620622167876 0.1621589929499346 33.082035078139235 0.7263654079083086 0.4580014435549171 7.468934423542768 0.0001633801259467489 3.786800773486595 -0.994867680643676 GNAEGSS(ph)DEEGKLVIDEPAK ddPTM_PC-9_AZD4547_30min_R2 3 GNAEGSSDEEGKLVIDEPAK 20 1 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 GNAEGS(0.221)S(0.779)DEEGKLVIDEPAK;GNAEGS(0.062)S(0.938)DEEGKLVIDEPAK;GNAEGS(0.266)S(0.734)DEEGKLVIDEPAK 144.25 0.00011409 50944500.0 162514.0 236518.0 155003.0 111873.9 145426.0 202432.0 241762.0 228278.0 217831.0 172587.0 True False 214190.0714988085 312967.8181384231 152947.55894283904 86083.10078952507 125236.11013548351 189773.89503894703 263278.3496449475 193002.88040658514 229345.10194919954 166544.78166139472 1.2860809528951938 1.8791811728735144 0.9183569573125356 0.5168766017811487 0.7519665815174166 1.1394766809612795 1.5808261719074668 1.1588647718724858 1.377077682418686 1.0 17.345550625271827 -7.0135029331089 24.33411968865517 1.3021052673070745 1.0631622484069283 0.06676557661071314 0.3642678403022371 1377.2557598310436 2482000.44725952 0.15164242542232625 0.12295025144775013 9.69386722299216e-08 7.0135029331089 -0.23894301890014624 GNAEGSS(ph)DEEGKLVIDEPAK ddPTM_PC-9_Lapatinib_30min_R1 2 GNAEGSSDEEGKLVIDEPAK 20 1 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 GNAEGS(0.062)S(0.938)DEEGKLVIDEPAK;GNAEGS(0.082)S(0.918)DEEGKLVIDEPAK 100.14 0.00015463 39359600.0 58440.0 146708.0 99343.0 98958.0 139586.0 129911.0 162617.0 175986.0 92471.0 147377.0 True False 57606.63488341656 146368.30663971262 91175.40201506959 106235.70143421089 131375.82591663493 124355.00936733211 171036.51256890787 184162.95202847902 82055.94221720111 172850.91808249123 0.3332735256628745 0.8467892925501266 0.5274799985242608 0.6146088352479044 0.7600528095195724 0.7194350527428789 0.9895030611713763 1.0654438754012823 0.47472089316899546 1.0 17.39916874080565 -6.61683943151064 1.476524980707618 0.8787961348305419 0.5918237647255676 0.3072469066303466 0.19416564515654744 0.5140277973009002 2.320105402736055 0.08015016254460942 0.08199214150728135 2.41635405003984e-07 6.61683943151064 -0.28697237010497423 GNDISSGTVLSDYVGSGPPK ddPTM_PC-9_Lapatinib_30min_R1 2 GNDISSGTVLSDYVGSGPPK 20 0 P30086 P30086 PEBP1 Phosphatidylethanolamine-binding protein 1;Hippocampal cholinergic neurostimulating peptide 0 ; 251.04 2.3947999999999997e-54 7157200.0 33240.0 32588.0 30264.0 31907.0 32374.0 31806.0 33429.0 30468.0 32565.0 30369.0 False True 32765.991504530553 32512.544488200765 27775.810742418354 34253.547218631764 30469.82496973291 30445.731523407318 35159.79005064678 31883.654508902444 28897.18677534746 35618.24118585113 0.9199216584997016 0.9128060062975804 0.7798198287638055 0.9616855318571577 0.8554556304660162 0.8547791948666312 0.9871287542579034 0.8951496044551407 0.8113030237671163 1.0 15.120328658058098 GNDPLTS(ph)SPGR ddPTM_PC-9_AZD4547_30min_R2 1 GNDPLTSSPGR 11 0 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 GNDPLT(0.056)S(0.472)S(0.472)PGR 71.976 0.028385000000000004 10094000.0 84653.0 80478.0 116620.0 157000.0 129250.0 128570.0 100020.0 129460.0 97377.0 101520.0 True False 111570.89310821611 106490.93966693441 115073.54260184562 120806.07562582 111305.86851739848 120530.49757527166 108921.58623558535 109454.93169484813 102524.14942091447 97965.81570028292 1.1388757630473534 1.087021415640873 1.1746295560269937 1.2331452023572658 1.1361704868352056 1.2303322002036223 1.1118325862647902 1.1172767859118844 1.046529839904333 1.0 16.57999080099023 -8.212721613588165 1.33425376013671 1.001548906419411 1.163667779282512 0.6240357164064956 0.04290450183622387 0.2861201011216226 0.9705995203844467 0.04190394366073542 0.013321117456473013 6.1274303930257995e-09 8.212721613588165 0.16211887286310112 GNDPLTS(ph)SPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GNDPLTSSPGR 11 0 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 GNDPLT(0.079)S(0.461)S(0.461)PGR;GNDPLT(0.043)S(0.478)S(0.478)PGR 70.54 0.031967 37370000.0 313580.0 364070.0 345330.0 328520.0 398520.0 329700.0 370300.0 319900.0 313170.0 261390.0 True False 366662.9005126854 400212.46354519273 353563.97687131737 310114.0894762097 320432.8667997563 312409.95159632113 335222.50326016353 311502.9639620672 317749.51879056776 308777.9378378981 1.187464697381248 1.2961174180627368 1.1450428723859507 1.004327225085016 1.0377453423112657 1.0117625429583954 1.0856426647817963 1.0088251969789361 1.0290551229647098 1.0 18.236210150265222 -5.5586117288535934 3.7651254280558666 1.0286706952619964 1.2402441975250609 0.8671878178028343 0.03433108917860254 0.06583834001386227 1.986802453359445 0.00897444089000741 0.01743042883033363 2.763046991908939e-06 5.5586117288535934 0.21157350226306448 GNDPLTS(ph)SPGR ddPTM_PC-9_Lapatinib_30min_R1 2 GNDPLTSSPGR 11 0 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 GNDPLT(0.069)S(0.465)S(0.465)PGR;GNDPLT(0.048)S(0.624)S(0.327)PGR 84.169 0.012155 21774000.0 194223.0 187556.0 232760.0 183784.0 218733.0 201214.0 184884.0 203734.0 241540.0 166541.0 True False 191453.34440386365 187121.72560540674 213623.37127958276 197300.08844545187 205867.55498562378 192608.5462727434 194456.38887564035 213200.22540753314 214335.22167104008 195327.38994806667 0.9801663988586903 0.9579902012470364 1.0936682834720752 1.0100994463598254 1.0539615311521826 0.9860805815505642 0.9955408144620276 1.0915019417615648 1.097312679640204 1.0 17.575534740976316 -7.7594112556748165 24.999827204282514 1.07080548729903 1.0128585292659626 0.2184386144214029 0.04412250275284151 74.55584657313658 919059.8008202022 0.022091625923626033 0.011925743194069098 1.7401582480137266e-08 7.7594112556748165 -0.057946958033067375 GNDPLTSS(ph)PGR ddPTM_PC-9_AZD4547_30min_R2 4 GNDPLTSSPGR 11 0 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 GNDPLT(0.043)S(0.213)S(0.744)PGR;GNDPLT(0.007)S(0.042)S(0.951)PGR;GNDPLTS(0.005)S(0.995)PGR;GNDPLTS(0.014)S(0.986)PGR 128.57 0.00030349 2059480000.0 795425.0 796860.0 1010211.0 1358489.0 1112766.0 1024604.0 913118.0 1219434.0 918466.0 926743.0 True False 1048353.6041321935 1054429.411553385 996814.9420798587 1045310.3494958272 958277.6486393176 960535.349907549 994383.7330560416 1030998.4951056342 967014.2376744985 894298.0096486176 1.172264270770441 1.1790582112194181 1.1146339713665712 1.1688613171648952 1.071541743692171 1.0740662950652848 1.1119154044038957 1.1528578661499294 1.081310958138498 1.0 19.770396139625745 -14.522878709217878 0.026917179562173755 0.24027987650695717 1.6623538140960548 0.6288514985682809 0.03314262107733867 1326.168354803001 2.682657303943236 105.81200472293213 46.904186469222836 3.0000002491106577e-15 14.522878709217878 1.4220739375890976 GNDPLTSS(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GNDPLTSSPGR 11 0 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 GNDPLT(0.009)S(0.058)S(0.933)PGR;GNDPLT(0.001)S(0.104)S(0.895)PGR;GNDPLTS(0.003)S(0.997)PGR;GNDPLT(0.001)S(0.007)S(0.992)PGR 148.13 0.00027484 1920420000.0 852514.0 885177.0 1091600.0 1028320.0 1191270.0 932960.0 1080570.0 883240.0 884560.0 771863.0 True False 996827.782280986 973051.5226290039 1117627.883916053 970706.5642584235 957849.1951032502 884033.9352177854 978210.5869506735 860055.8858701376 897495.0165768893 911795.651835855 1.093257881054733 1.067181578097914 1.2257438184375689 1.0646097755609543 1.0505086234779346 0.9695526990481116 1.0728397146675304 0.9432550858719913 0.9843159646241216 1.0 19.798351003742795 -6.309499827207801 2.185676279606037 0.9962491385138014 1.1225475802128948 0.5452937156662192 0.05152511474635164 0.24503198478388702 2.2980744137206663 0.017591980844267194 0.021875452335166287 4.903432178840961e-07 6.309499827207801 0.12629844169909343 GNDPLTSS(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 5 GNDPLTSSPGR 11 0 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 GNDPLT(0.008)S(0.047)S(0.945)PGR;GNDPLT(0.001)S(0.005)S(0.994)PGR;GNDPLTS(0.003)S(0.997)PGR;GNDPLT(0.001)S(0.225)S(0.774)PGR;GNDPLT(0.001)S(0.124)S(0.875)PGR 153.49 0.00014423 1972483800.0 750183.0 870562.0 886574.0 750943.0 840899.0 796679.0 727613.0 732776.0 826170.0 625134.0 True False 739485.2528532882 868546.267176168 813683.3079946077 806169.8532924138 791438.9740910423 762606.8963194557 765285.2409022482 766823.4480903073 733118.0346442144 733187.5789613031 1.0085894443287036 1.1846167230582736 1.1097887243907512 1.0995410675594146 1.079449511695579 1.0401252260708378 1.0437782401966185 1.0458762124375534 0.9999051479879307 1.0 19.48382281961259 -6.951129707465827 0.8280002765626462 1.0116241651267488 1.110706077019948 0.43242423449610357 0.041707710828714266 0.5709749307017807 0.8248865280891835 0.0288651456670423 0.02260228180570964 1.1191035992972865e-07 6.951129707465827 0.09908191189319915 GNDSDGEGES(ph)DDPEKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GNDSDGEGESDDPEKK 16 1 K7EKZ3;O75351 K7EKZ3 VPS4B Vacuolar protein sorting-associated protein 4B 1 GNDS(0.036)DGEGES(0.964)DDPEKK 83.292 0.0082845 3546500.0 20477.0 23535.0 22458.0 32821.0 33793.0 27417.0 25056.0 39324.0 23853.0 19891.0 True False 23943.35166081468 25871.39926260359 22993.4838924393 30982.145777117697 27171.504235080254 25979.20425512993 22682.514290269122 38291.786667222084 24201.80499955748 23497.08084293063 1.0189926068207027 1.101047378418809 0.9785676802213138 1.3185529719296614 1.156377867391775 1.1056353948301658 0.9653332872237795 1.6296401635245092 1.0299919875723147 1.0 14.520193914423919 -5.743080468649055 24.999910397843504 1.1863992689376381 1.0396870320427563 0.10417528843733204 0.18367315273820373 544.6408013480583 741648.840584652 0.04877833538621041 0.08428520045846885 1.8068393131242815e-06 5.743080468649055 -0.1467122368948819 GNDT(ph)PLALESTNTEK ddPTM_PC-9_AZD4547_30min_R2 1 GNDTPLALESTNTEK 15 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 GNDT(0.999)PLALES(0.001)TNTEK 104.78 0.0027272 5158400.0 19021.0 20184.0 27098.0 24189.0 27214.0 31572.0 28768.0 38248.0 32747.0 26800.0 True False 25069.28233862209 26708.08328036736 26738.662814481333 18612.599766324598 23435.805847833555 29597.797849004248 31328.29626899948 32337.65045160325 34477.939565674475 25861.740157285138 0.9693579080973089 1.0327256834975125 1.0339081071831575 0.7196963411250388 0.9061960140849916 1.144462734100539 1.2113761904059048 1.2504050483429623 1.3331639462769171 1.0 14.658531732494263 -6.870069242887674 4.026938106702745 1.214760975796446 0.9318886814778834 0.5578500302996018 0.1139411578126341 0.17021068337361311 5.073485015618051 0.04321771171194583 0.03811175590619092 1.3487478242765682e-07 6.870069242887674 -0.28287229431856253 GNDT(ph)PLALESTNTEK ddPTM_PC-9_Lapatinib_30min_R1 2 GNDTPLALESTNTEK 15 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 GNDT(1)PLALESTNTEK;GNDT(1)PLALESTNTEK 160.09 0.00011649 10708900.0 32833.0 50284.0 50857.0 45955.0 56991.0 53120.0 55955.0 54798.0 56049.0 50021.0 True False 32364.795399165236 50167.57048743978 46675.73377369717 49334.68400138601 53638.901428617 50848.181428768024 58852.07611008229 57344.11512993425 49736.17139786429 58667.06320120715 0.5516689200576737 0.8551232625260764 0.7956037208410451 0.840926429744499 0.9142932763594226 0.8667245069755214 1.0031536078129668 0.9774499012037529 0.847769918655838 1.0 15.840263153881894 -4.0087716207619275 0.5743284438468108 0.9415312618019759 5.1149352008473205e-24 0.7281391896014268 0.0651971609590899 4.690007178777775 0.6076293898184322 0.03207484812814257 3.5727089817290696 9.800051980412994e-05 4.0087716207619275 -0.9415312618019759 GNDVAFHFNPR ddPTM_PC-9_AZD4547_30min_R2 4 GNDVAFHFNPR 11 0 P17931;G3V3R6 P17931 LGALS3 Galectin-3;Galectin 0 ;;; 124.12 0.00044257 31137400.0 192925.0 206677.0 261896.0 371187.0 326482.0 267370.0 242694.0 303614.0 242993.0 262458.0 False True 254271.1369107129 273481.29846098315 258423.08792019344 285615.57193198265 281155.6097895344 250651.3116333544 264293.2958394246 256697.4326556444 255837.1138999583 253269.42530599734 1.0039551225083931 1.0798038418200935 1.0203485383518738 1.127714376051926 1.1101048199949335 0.9896627329987433 1.0435262587266834 1.0135350224193282 1.0101381704122347 1.0 17.950313399802326 -6.771690153336409 24.99981091566471 1.0142279898234852 1.0696470503794973 0.37366992442659897 0.03679547456313015 246.6944981623454 601640.0644213513 0.013235218611460329 0.011799690498864384 1.6916474041936252e-07 6.771690153336409 0.05541906055601209 GNDVAFHFNPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GNDVAFHFNPR 11 0 P17931;G3V3R6 P17931 LGALS3 Galectin-3;Galectin 0 ;;; 107.03 0.0019814 14094500.0 114639.0 107568.0 125774.0 138997.0 151361.0 118617.0 126984.0 126496.0 111985.0 105768.0 False True 134045.11847654122 118246.64014785399 128772.92916055152 131209.44872435427 121702.8986040298 112396.51570670573 114955.15623545398 123175.61403359052 113622.568770194 124942.9011409724 1.0728510163638576 0.946405430544925 1.030654226727597 1.0501552911462442 0.9740681342648917 0.89958304697831 0.920061525590403 0.9858552419445754 0.9093959539325429 1.0 16.930909408837387 -6.503049383108916 7.021564697215282 0.9401461385150427 1.0190803263341808 0.4519532835482307 0.04235884660395806 0.16208463123379818 36.45928663510867 0.013146907735495183 0.014278912804563667 3.1401516106706116e-07 6.503049383108916 0.07893418781913808 GNDVAFHFNPR ddPTM_PC-9_Lapatinib_30min_R1 3 GNDVAFHFNPR 11 0 P17931;G3V3R6 P17931 LGALS3 Galectin-3;Galectin 0 ;; 111.63 0.0015007999999999998 10171500.0 137822.0 133223.0 154998.0 129979.0 142358.0 142717.0 108813.0 111941.0 151190.0 113966.0 False True 135856.63300654062 132914.53032869688 142254.66274958217 139538.08925723354 133984.7823265964 136613.32659957604 114446.80471390192 117142.18752071212 134161.39009871896 133664.8712498502 1.0163974403760396 0.994386401496989 1.0642636424919432 1.0439398770407293 1.0023933818493584 1.0220585657409904 0.8562220098949909 0.8763872394097219 1.0037146547497933 1.0 17.02826083191954 -7.208979234337757 14.209269099428305 0.9237850384418977 1.0243421755780397 0.45776981786146786 0.047364536731171074 2.645194867607646 715.8219578962753 0.018070547542759427 0.013995460338441726 6.180459511163382e-08 7.208979234337757 0.100557137136142 GNEEKPAS(ph)PSAAVPPGTDHDPHGLVVK ddPTM_PC-9_AZD4547_30min_R2 2 GNEEKPASPSAAVPPGTDHDPHGLVVK 27 1 Q52LW3 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 GNEEKPAS(0.815)PS(0.173)AAVPPGT(0.012)DHDPHGLVVK;GNEEKPAS(0.887)PS(0.057)AAVPPGT(0.057)DHDPHGLVVK 78.428 1.4484e-05 17641300.0 86045.0 83510.0 93591.0 136572.0 131143.0 116874.0 110352.0 154473.0 114602.0 122690.0 True False 113405.52015281719 110502.97437294277 92349.92218872685 105087.43541636634 112936.05814295704 109565.85030421018 120173.11421984929 130602.74728640715 120659.62775538002 118394.66044392987 0.9578600903756511 0.933344240007137 0.7800176278427906 0.8876028278837317 0.9538948607943519 0.9254289838189038 1.015021401887982 1.103113491746183 1.0191306542284717 1.0 16.85324449184988 -7.1495688038452005 1.6749475417329456 1.0489708295451898 0.8934078282778092 0.5829297466710222 0.05330468405422299 0.26767601902018184 1.481213169771036 0.029126845668304733 0.01950934946469382 7.086490286245695e-08 7.1495688038452005 -0.15556300126738065 GNEEKPAS(ph)PSAAVPPGTDHDPHGLVVK ddPTM_PC-9_Lapatinib_30min_R1 2 GNEEKPASPSAAVPPGTDHDPHGLVVK 27 1 Q52LW3 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 GNEEKPAS(0.369)PS(0.369)AAVPPGT(0.263)DHDPHGLVVK;GNEEKPAS(0.862)PS(0.13)AAVPPGT(0.008)DHDPHGLVVK 51.871 0.0054348999999999995 17142800.0 89004.0 66965.0 66320.0 62775.0 98873.0 94476.0 102034.0 91550.0 92577.0 100399.0 True False 87734.7866386654 66809.94665681741 60867.425602603325 67391.68291126123 93057.4845317972 90435.48171431264 107316.8212638037 95803.74721970632 82150.00338097173 117752.83337674136 0.7450758009190703 0.5673744294802996 0.5169083737277265 0.5723147458851083 0.790278092367143 0.768011088318963 0.9113735796101956 0.8136003565467458 0.697647784984833 1.0 16.845402248919406 -6.337530853497791 3.924165191628201 0.8263509939492141 0.5915448393707021 0.5906277600568237 0.0938545812677676 0.1690290411757296 4.996739220722898 0.029826813946001764 0.034631083937639306 4.5969432939660776e-07 6.337530853497791 -0.23480615457851195 GNFNS(ph)TVNNTVTVR ddPTM_PC-9_AZD4547_30min_R2 1 GNFNSTVNNTVTVR 14 0 Q96BY6;A0A2R8YD85;Q96BY6-3;Q96BY6-2 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 GNFNS(0.601)T(0.364)VNNT(0.035)VT(0.001)VR 87.647 0.0060269 9628500.0 27952.0 21464.0 39942.0 67948.0 61920.0 35814.0 38509.0 43265.0 38064.0 41025.0 True False 36840.15456228194 28401.818248603122 39412.34298236081 52283.63838613512 53323.476817000555 33574.544918416235 41936.22639818204 36579.38838079411 40075.98533080388 39588.72723703814 0.9305718353030378 0.7174218579583723 0.9955445838503161 1.320669848087967 1.3469358713586668 0.8480834636937962 1.059297161716976 0.9239849556611011 1.0123080009834182 1.0 15.272802065550202 -5.5105333595061525 24.05849968845765 1.0780135947677185 0.8321183499229577 0.28583589284560995 0.15536922472324746 459.61674962598573 895691.208391404 0.04462749307318338 0.08586316327345826 3.086502552743954e-06 5.5105333595061525 -0.24589524484476077 GNFNST(ph)VNNTVTVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GNFNSTVNNTVTVR 14 0 Q96BY6;A0A2R8YD85;Q96BY6-3;Q96BY6-2 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 GNFNS(0.21)T(0.679)VNNT(0.111)VTVR 78.902 0.039306 0.0 4712.6 6304.8 9425.1 8398.6 8237.3 6760.1 7365.6 8819.2 9289.0 5326.1 True False 5510.350101907275 6930.698877028385 9649.830128890797 7928.053670628579 6623.260196952821 6405.588455524089 6667.877045673935 8587.705344714806 9424.834051938522 6291.679768615599 0.8758154109168456 1.1015657395025675 1.5337446411412186 1.260085376591416 1.0527014152867769 1.018104654257309 1.0597928201837128 1.364930457451495 1.4979837497375257 1.0 12.619229527572829 -7.769204101764066 24.995160649867902 1.3235928670141417 1.1412166129543497 0.10558955401255332 0.20166128052352303 382.6924935589841 1231889.6085498433 0.11297271593009883 0.05586219918395643 1.7013587470670626e-08 7.769204101764066 -0.18237625405979196 GNFNYIEFTR ddPTM_PC-9_AZD4547_30min_R2 2 GNFNYIEFTR 10 0 J3QRS3;P19105;O14950 J3QRS3 MYL12A;MYL12B Myosin regulatory light chain 12A;Myosin regulatory light chain 12B 0 ; 148.91 0.00060268 22007000.0 53249.0 48381.0 65924.0 83075.0 81734.0 65197.0 52807.0 59545.0 58012.0 59479.0 False True 70181.07435199447 64019.212107979285 65049.804686023606 63923.3422459554 70386.64493153628 61120.2212834641 57506.72069928583 50343.68845797729 61078.3958861547 57396.65831399863 1.2227379853380385 1.1153822189046407 1.1333378387667985 1.1137119150082115 1.2263195628301846 1.064874211824233 1.0019175747947742 0.8771188068574164 1.0641455039423109 1.0 15.80867912386919 -7.078863961683124 3.0471338490568733 0.9752764261922636 1.155237554362443 0.6728510475588362 0.057515340940944994 0.1508366682136696 2.721822320888744 0.022787286946506006 0.017546556181328832 8.339423676519216e-08 7.078863961683124 0.17996112817017929 GNFNYIEFTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GNFNYIEFTR 10 0 J3QRS3;P19105;O14950 J3QRS3 MYL12A;MYL12B Myosin regulatory light chain 12A;Myosin regulatory light chain 12B 0 121.5 0.0028428 8994700.0 13319.0 13156.0 16095.0 19036.0 21660.0 18420.0 17289.0 15109.0 16751.0 14387.0 False True 15573.643637758974 14462.040735024986 16478.765840627402 17969.474635544684 17415.878487611004 17454.02277344325 15651.260758479511 14712.404759308774 16995.95168522146 16995.249212570656 0.9163527667625974 0.8509460822926936 0.9696101324856576 1.0573233973087866 1.0247498150676853 1.0269942238053948 0.9209197560282285 0.8656774946510722 1.0000413334716083 1.0 14.052843896774943 -5.342758220568659 6.29224003855643 0.982398806319 0.8841469296054382 0.34940571030384215 0.054445850467059756 0.26804332398717895 16.76110657811152 0.01605112204546628 0.03402402385460838 4.541944043486606e-06 5.342758220568659 -0.09825187671356184 GNFNYIEFTR ddPTM_PC-9_Lapatinib_30min_R1 2 GNFNYIEFTR 10 0 J3QRS3;P19105;O14950 J3QRS3 MYL12A;MYL12B Myosin regulatory light chain 12A;Myosin regulatory light chain 12B 0 ; 154.84 0.00073379 35853000.0 123851.0 98221.0 100476.0 82602.0 107024.0 97779.0 94576.0 98796.0 94889.0 87559.0 False True 122084.86202850805 97993.57530918033 92215.2511285763 88676.8266321943 100729.05873727969 93597.22010398173 99472.68251607796 103386.42283253 84201.60159453227 102693.45648496608 1.1888280539703209 0.9542338788014815 0.89796618289965 0.8635100002226163 0.9808712471570769 0.9114234081475677 0.968637008830649 1.0067479114179527 0.819931517319792 1.0 16.647984732067158 -4.763733039505489 4.556720405860731 0.9310124546520172 1.209335244923893 0.6430350169838659 0.0572515079725464 0.12035197178986903 5.628066732917485 0.013822184231931685 0.10965288383636344 1.722927331691537e-05 4.763733039505489 0.2783227902718758 GNFS(ph)PLELDNVLLK ddPTM_PC-9_Lapatinib_30min_R1 3 GNFSPLELDNVLLK 14 0 Q52LW3;F8VWZ8;Q52LW3-2 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 GNFS(1)PLELDNVLLK;GNFS(1)PLELDNVLLK;GNFS(1)PLELDNVLLK 141.1 0.00012891 3758400.0 5809.1 11294.3 10581.94 8740.3 12207.8 12708.5 10223.0 10647.94 11722.399999999998 9923.5 True False 5726.261168741527 11268.148742269725 9711.93374066966 9383.090818786075 11489.761205458242 12164.987079960434 10752.29691847683 11142.682164616073 10402.09986965555 11638.76375276742 0.4919990894548366 0.9681568405055415 0.8344471927579417 0.8061930818515841 0.9871977341860085 1.0452129915488568 0.923834966228281 0.9573767799837513 0.8937461134720756 1.0 13.506650205624696 -4.7585186842570515 24.98339035510009 0.9313362638356838 0.491998490621587 0.7815715338292551 0.07025283762396428 39.2452717482053 335639.5039895849 0.018763212284892323 0.1277233044092179 1.7437383365813496e-05 4.7585186842570515 -0.4393377732140968 GNGSGGS(ph)RENSTVDFSK ddPTM_PC-9_AZD4547_30min_R2 2 GNGSGGSRENSTVDFSK 17 1 Q9Y6M7-7;Q9Y6M7-2;C9JRP1;Q9Y6M7;Q9Y6M7-13;Q9Y6M7-9;Q9Y6M7-11;Q9Y6M7-6;Q9Y6M7-14;Q9Y6M7-3;Q9Y6M7-4;Q9Y6M7-12;Q9Y6M7-10;Q9Y6M7-8;A0A0A0MST8;E9PFN4 Q9Y6M7-7 SLC4A7 Sodium bicarbonate cotransporter 3;Anion exchange protein 1 GNGS(0.265)GGS(0.622)RENS(0.052)T(0.061)VDFSK;GNGS(0.028)GGS(0.972)RENSTVDFSK 110.37 0.005363199999999999 8958100.0 24524.0 48882.0 52727.0 41807.0 43423.0 33169.0 47208.0 53801.0 42277.0 32203.0 True False 32322.121869111386 64682.15056039032 52027.805528790195 32169.04206171121 37394.46598553969 31094.937186545718 51409.42054598606 45487.2916739883 44511.67590979389 31075.582771830334 1.0401131366202736 2.081446099830635 1.6742342665236456 1.0351870887799435 1.2033391701808196 1.000622817433787 1.6543348816160617 1.4637631097049617 1.4323681791140286 1.0 14.92349382647149 -5.737729708082605 24.68423880398677 1.2787877241031838 1.6468829661275204 0.19475795457146494 0.31252737133561315 312.393162313145 325230.7225861654 0.08466785627901789 0.14653939233843707 1.8292383252555691e-06 5.737729708082605 0.36809524202433663 GNGSGGS(ph)RENSTVDFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GNGSGGSRENSTVDFSK 17 1 Q9Y6M7-7;Q9Y6M7-2;C9JRP1;Q9Y6M7;Q9Y6M7-13;Q9Y6M7-9;Q9Y6M7-11;Q9Y6M7-6;Q9Y6M7-14;Q9Y6M7-3;Q9Y6M7-4;Q9Y6M7-12;Q9Y6M7-10;Q9Y6M7-8;A0A0A0MST8;E9PFN4 Q9Y6M7-7 SLC4A7 Sodium bicarbonate cotransporter 3;Anion exchange protein 1 GNGS(0.011)GGS(0.98)RENS(0.006)T(0.002)VDFSK 120.08 0.00043593 3787900.0 14888.0 10580.0 10559.0 10183.0 19374.0 8593.3 7080.7 9120.9 6710.6 7936.3 True False 17408.244348596407 11630.31247921589 10810.766605230498 9612.479523731432 15577.803777422683 8142.65222035993 6409.964836171321 8881.48603939237 6808.729829792081 9375.088366283773 1.8568618948918694 1.2405549713048811 1.1531375687198795 1.0253214847874292 1.6616167409627978 0.8685413835291268 0.6837231379305058 0.9473495814005789 0.7262576696640801 1.0 13.194616573557814 -6.8565370656209135 8.357771297277038 0.8277578585923561 1.3454505799029528 0.5526572114544034 0.2424093808945807 0.21195587564274387 16.557633744600068 0.0858703037273901 0.07577907246787516 1.3914350353240917e-07 6.8565370656209135 0.5176927213105967 GNGSGGS(ph)RENSTVDFSK ddPTM_PC-9_Lapatinib_30min_R1 1 GNGSGGSRENSTVDFSK 17 1 Q9Y6M7-7;Q9Y6M7-2;C9JRP1;Q9Y6M7;Q9Y6M7-13;Q9Y6M7-9;Q9Y6M7-11;Q9Y6M7-6;Q9Y6M7-14;Q9Y6M7-3;Q9Y6M7-4;Q9Y6M7-12;Q9Y6M7-10;Q9Y6M7-8;A0A0A0MST8;E9PFN4 Q9Y6M7-7 SLC4A7 Sodium bicarbonate cotransporter 3;Anion exchange protein 1 GNGS(0.137)GGS(0.86)RENS(0.003)TVDFSK 108.75 0.0024292 5480400.0 30716.0 45121.0 17315.0 13234.0 16693.0 12911.0 11717.0 8795.1 22659.0 6858.4 True False 30277.98420737547 45016.525096725956 15891.427537832877 14207.272507329837 15711.15055970072 12358.826627010994 12323.648928278695 9203.752454091105 20106.904810151962 8043.865301756442 3.764108804850826 5.596379776137753 1.9755959282862254 1.7662245667176408 1.9531841932099565 1.536428839044874 1.5320556058525405 1.1441952480334787 2.4996570747848623 1.0 12.973673207912134 -5.331118058665506 6.2562138665171805 1.6693853088741222 4.669669308514831 0.8151190948375127 0.5729090122256263 0.07461257126799241 5.326538941872601 0.13974118923172998 0.29728512762320236 4.66532540811622e-06 5.331118058665506 3.0002839996407094 GNHECASINR ddPTM_PC-9_AZD4547_30min_R2 4 GNHECASINR 10 0 P62136-3;P62136;P62136-2;E9PMD7;F8VR82;F8VYE8;F8W0W8;P36873;P36873-2;C9JP48;A0A087WYY5;E7ETD8;P62140 P62136-3;P62140 PPP1CA;PPP1CC;PPP1CB Serine/threonine-protein phosphatase PP1-alpha catalytic subunit;Serine/threonine-protein phosphatase;Serine/threonine-protein phosphatase PP1-gamma catalytic subunit;Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0 ;;; 131.09 0.00016068 18520800.0 54391.299999999996 55256.6 83294.0 114363.0 92434.5 84066.09999999999 62138.6 92404.1 71258.5 83674.5 False True 71686.60199067857 73117.21534829302 82189.46713666731 87998.37724073663 79601.56521061128 78809.43347758056 67668.81502158138 78125.16957997765 75025.07883288905 80745.08122353573 0.8878138569483935 0.9055315102832625 1.0178882216878689 1.0898295711304171 0.9858379483233323 0.976027669839151 0.838054950173945 0.9675532973172064 0.929159741943768 1.0 16.3010867568724 -7.03699297651242 24.9958953891767 0.9275671310620824 0.9817909558426434 0.09164550514393699 0.06519149655282676 1302.9555597649342 880393.6834070882 0.026710262166035025 0.02069610452547237 9.183474480417039e-08 7.03699297651242 0.05422382478056098 GNHECASINR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GNHECASINR 10 0 P62136-3;P62136;P62136-2;E9PMD7;F8VR82;F8VYE8;F8W0W8;P36873;P36873-2;C9JP48;A0A087WYY5;E7ETD8;P62140 P62136-3;P62140 PPP1CA;PPP1CC;PPP1CB Serine/threonine-protein phosphatase PP1-alpha catalytic subunit;Serine/threonine-protein phosphatase;Serine/threonine-protein phosphatase PP1-gamma catalytic subunit;Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0 ; 104.82 0.0021393000000000002 2107530.0 6209.0 8315.0 9447.3 9900.6 10679.2 6756.799999999999 9384.7 5970.3 7479.700000000001 7591.2 False True 7260.061066660068 9140.458248079403 9672.559461084771 9345.901480178287 8586.687421278637 6402.461513333401 8495.71327665583 5813.585951055739 7589.076462297825 8967.42446809386 0.8096038157323099 1.0192958168313766 1.0786329447769296 1.0422057652596965 0.9575422075569316 0.7139688252868358 0.947397249554052 0.6483005205943476 0.8462938817382624 1.0 13.130477973189985 -6.604730565394612 7.0103121245493165 0.8170552127871508 0.9966679194809005 0.2926323539151139 0.1160947872455708 0.24577228905954937 17.536525770659928 0.03726887689089516 0.03725053986128073 2.4846741093715723e-07 6.604730565394612 0.17961270669374974 GNHECASINR ddPTM_PC-9_Lapatinib_30min_R1 3 GNHECASINR 10 0 P62136-3;P62136;P62136-2;E9PMD7;F8VR82;F8VYE8;F8W0W8;P36873;P36873-2;C9JP48;A0A087WYY5;E7ETD8;P62140 P62136-3;P62140 PPP1CA;PPP1CC;PPP1CB Serine/threonine-protein phosphatase PP1-alpha catalytic subunit;Serine/threonine-protein phosphatase;Serine/threonine-protein phosphatase PP1-gamma catalytic subunit;Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0 ;; 152.69 0.00010564 22805100.0 90122.6 92894.5 113555.1 104751.2 107959.2 105932.8 102490.4 99105.0 110893.3 86604.8 False True 88837.43519753918 92679.408492671 104219.03801336225 112454.95268775949 101609.25211195357 101402.30108541784 107796.85142262142 103709.78010059014 98403.32879578193 101574.32428635798 0.8746052294385832 0.9124294859337635 1.0260372268837181 1.107119869886871 1.0003438647103093 0.9983064302701619 1.06126082728073 1.0210235788348627 0.9687815251260112 1.0 16.632176241644622 -5.193214857314402 3.8434745449202135 1.0266133148162062 0.8841310874414587 0.6686785524879645 0.03668866462250518 0.13233278673618615 3.821449366278212 0.009866369481436483 0.029393618715760128 6.408924311918394e-06 5.193214857314402 -0.14248222737474747 GNIDGNVS(ph)CSENLVANTAR ddPTM_PC-9_AZD4547_30min_R2 1 GNIDGNVSCSENLVANTAR 19 0 Q92576-2;Q92576 Q92576-2 PHF3 PHD finger protein 3 1 GNIDGNVS(0.987)CS(0.013)ENLVANTAR 103.73 0.00027442 3308000.0 5200.7 4847.5 10021.0 11189.0 10594.0 5717.7 8731.3 8317.8 5918.1 10596.0 True False 6854.414418719935 6414.359576970907 9888.114992394914 8609.548918326753 9123.20596575104 5360.171315128957 9508.368785230641 7032.475134029105 6230.9186839593885 10225.037265171386 0.6703559352362952 0.6273189437479663 0.9670492865660159 0.8420066054578281 0.8922418304358251 0.524220222980196 0.9299104285534618 0.687770122656001 0.6093785794975242 1.0 13.319818480631387 GNIDGNVS(ph)CSENLVANTAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GNIDGNVSCSENLVANTAR 19 0 Q92576-2;Q92576 Q92576-2 PHF3 PHD finger protein 3 1 GNIDGNVS(0.921)CS(0.079)ENLVANTAR 147.28 3.5735000000000005e-14 0.0 5450.6 6288.3 9410.1 8827.0 8842.1 8970.4 9088.6 6720.1 7726.5 7003.7 True False 6373.278925742854 6912.560866073092 9634.472472002977 8332.451807520114 7109.553978545951 8499.976432513315 8227.662012234186 6543.704495534506 7839.485445398101 8273.415368741307 0.7703322801635748 0.8355147853678654 1.1645097027769242 1.0071356792990063 0.8593251591606693 1.027384224491859 0.9944698344676388 0.7909314598488539 0.9475512948397726 1.0 13.01426729947257 -5.017836411651494 24.35457437621 0.9684397712412716 0.7866277771248983 0.35172535108429404 0.09444888723787356 528.8260786066938 722089.3928755954 0.025021343887464974 0.06952089577312436 9.59762082867873e-06 5.017836411651494 -0.18181199411637328 GNIDGNVS(ph)CSENLVANTAR ddPTM_PC-9_Lapatinib_30min_R1 1 GNIDGNVSCSENLVANTAR 19 0 Q92576-2;Q92576 Q92576-2 PHF3 PHD finger protein 3 1 GNIDGNVS(0.913)CS(0.087)ENLVANTAR 123.43 2.6586e-05 3210100.0 18739.0 20857.0 23442.0 13784.0 18226.0 20858.0 20770.0 16229.0 20097.0 13677.0 True False 18471.778423688276 20808.706897950266 21514.68924873682 14797.721342076044 17153.982513694697 19965.95196237279 21845.3689716095 16983.058586877312 17833.464229207977 16041.051226543039 1.1515316647778748 1.2972159121042026 1.3412268899893907 0.9224907478376689 1.069380196561563 1.2446785238946958 1.3618414817765863 1.0587247897304597 1.1117391234122513 1.0 13.969481069323914 -14.522878743781257 0.14923150111007097 0.35378659164029863 1.23211368502066 0.15405930099219323 0.13081566611327053 287.29260942219315 2.5433503455122466 54.6238458374776 0.7281131163187314 3.0000000103552787e-15 14.522878743781257 0.8783270933803613 GNIETT(ph)SEDGQVFSPK ddPTM_PC-9_AZD4547_30min_R2 1 GNIETTSEDGQVFSPK 16 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 GNIET(0.12)T(0.66)S(0.218)EDGQVFS(0.002)PK 91.59200000000001 0.0078993 6320800.0 32090.0 41992.0 48478.0 70618.0 55075.0 51057.0 49505.0 57444.0 36791.0 43801.0 True False 42293.95248653504 55565.09280168381 47835.15004503747 54338.111137223925 47428.78691370006 47864.39771875741 53910.84909610745 48567.34973180026 38735.69714968487 42267.5403219868 1.000624880566672 1.3146043601874762 1.13172305936512 1.2855754255697305 1.1221089884198554 1.1324150247242855 1.2754669111432542 1.1490460377354017 0.9164407688406526 1.0 15.367262539504605 -8.185275734847615 5.2029825071217966 0.9592536080773122 1.1849843072835529 0.4800457389461189 0.09093711330915957 0.15820277887316248 7.531565980789621 0.061041374421358346 0.021669214155548837 6.527160097442148e-09 8.185275734847615 0.22573069920624067 GNIETT(ph)SEDGQVFSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GNIETTSEDGQVFSPK 16 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 GNIET(0.063)T(0.62)S(0.314)EDGQVFS(0.003)PK 114.06 0.0016069000000000003 0.0 9709.8 14020.0 11510.0 11828.0 14486.0 10002.0 13156.0 11973.0 9409.0 7907.7 True False 11353.477362708314 15411.8129450479 11784.442051918086 11165.315506893394 11647.572288621093 9477.477512485311 11909.768438808294 11658.721436442114 9546.588824920822 9341.303412681245 1.2154061228003203 1.6498567987980843 1.2615415142088382 1.1952631248157477 1.2468894086888327 1.0145776337399772 1.2749578846395504 1.2480829410395629 1.0219760993911078 1.0 13.189408151065471 -3.602872170615971 0.18185014172564243 0.9842324962915028 2.0574970940363206 0.38827492010814146 0.14012307714682354 27.646335598294606 0.6093303142471805 0.3521754342510199 7.162236367342798 0.00024953290891208455 3.602872170615971 1.0732645977448179 GNIETT(ph)SEDGQVFSPK ddPTM_PC-9_Lapatinib_30min_R1 1 GNIETTSEDGQVFSPK 16 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 GNIET(0.001)T(0.719)S(0.28)EDGQVFSPK 197.51 1.4762e-11 5596600.0 34699.0 30037.0 28793.0 23918.0 28343.0 31002.0 28298.0 27318.0 27056.0 18515.0 True False 34204.18589698273 29967.451171967765 26425.75068419415 25677.00950810903 26675.920464481995 29676.11672919177 29763.131976822613 28587.29400926207 24008.668367689283 21715.293080313255 1.5751196988444844 1.3800159666799887 1.216918905329043 1.1824390033854715 1.2284393475981206 1.366599871318139 1.3706069665624454 1.3164590458684098 1.1056110676882904 1.0 14.406423803796985 -14.307596922079277 0.0651586916532077 4.6422468530761574e-17 1.7083320433399034 0.5098236594061492 0.10818490013576343 349.155110610185 1.7078424951525075 55.45372695120541 8.4344363324846 4.924964200006656e-15 14.307596922079277 1.7083320433399034 GNIETTS(ph)EDGQVFSPK ddPTM_PC-9_AZD4547_30min_R2 1 GNIETTSEDGQVFSPK 16 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 GNIET(0.026)T(0.134)S(0.704)EDGQVFS(0.136)PK 79.492 0.008871700000000001 5806900.0 23132.0 30108.0 30734.0 41275.0 32284.0 37377.0 31224.0 43692.0 21731.0 23162.0 True False 30487.49482451009 39839.82220597011 30326.447078761135 31759.68644239316 27801.923862403873 35039.81028133254 34002.875511097045 36940.405342278005 22879.65629528422 22351.105429964104 1.3640262634902283 1.7824542204771878 1.3568209041735007 1.4209447734882867 1.2438724317022973 1.5676992080381777 1.5213062109005342 1.652732812613167 1.0236476386806148 1.0 14.448058564823333 -8.27560811908581 23.98529729172677 1.0118235126013349 1.4874222678534599 0.6250783310660715 0.14773714455214046 341.4713094178021 578043.9367496355 0.14021229751061606 0.03700076993396946 5.3014159564914595e-09 8.27560811908581 0.475598755252125 GNIETTS(ph)EDGQVFSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GNIETTSEDGQVFSPK 16 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 GNIET(0.051)T(0.19)S(0.73)EDGQVFS(0.03)PK 70.41 0.019802 4606500.0 6704.5 7286.6 7317.0 7855.4 10933.0 8961.6 7966.6 6874.8 5265.9 6094.7 True False 7839.4394300889735 8009.9654925382365 7491.465029877031 7415.287405550419 8790.757133197185 8491.637920004836 7211.945974810742 6694.34378445271 5342.903825395954 7199.620864381348 1.0888683692877492 1.1125537918483879 1.0405360464103772 1.029955263649512 1.2210027859505295 1.179456263039555 1.0017119110383117 0.9298189322123345 0.7421090535237597 1.0 12.813705220178337 -7.655533067835544 2.6529305802323466 0.8684420636085677 1.1090808794577387 0.5999400071518826 0.08090521543300318 0.18690144277848453 2.639489049990327 0.047887617529958654 0.02353036518697079 2.2103799482355875e-08 7.655533067835544 0.24063881584917102 GNIETTS(ph)EDGQVFSPK ddPTM_PC-9_Lapatinib_30min_R1 1 GNIETTSEDGQVFSPK 16 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 GNIET(0.002)T(0.034)S(0.964)EDGQVFSPK 113.14 0.00026808 5303800.0 34569.0 32360.0 31692.0 29118.0 30611.0 35837.0 32414.0 35877.0 31177.0 22806.0 True False 34076.03972082182 32285.072408192456 29086.40609465778 31259.434854800507 28810.521163541525 34304.335050127265 34092.23831707993 37543.97639542775 27665.51795163546 26747.98671291516 1.2739665263991005 1.207009437932902 1.0874241267890836 1.1686649612289142 1.0771098951395275 1.2825015736067924 1.2745721269787615 1.4036187769339585 1.0343028149583038 1.0 14.707142685321115 -6.778522810348338 24.997351889705357 1.2289485280895052 1.1614234885769634 0.0 0.12375164070228743 753.9211422207138 1103169.1136208712 0.04243376781607964 0.03751347819720291 1.665241362402257e-07 6.778522810348338 -0.06752503951254174 GNIETTSEDGQVFS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 5 GNIETTSEDGQVFSPK 16 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 GNIETTSEDGQVFS(1)PK;GNIETTSEDGQVFS(1)PK;GNIET(0.006)T(0.029)S(0.029)EDGQVFS(0.936)PK;GNIET(0.002)T(0.018)S(0.027)EDGQVFS(0.953)PK;GNIETTS(0.001)EDGQVFS(0.999)PK 188.1 9.4691e-15 164641000.0 215836.0 191476.2 219262.6 282626.0 279796.0 242536.0 240108.0 236980.0 230408.0 248793.0 True False 284467.3583323086 253367.13712882868 216355.03466036206 217470.94222817215 240951.1550305157 227370.1855791866 261477.14684916977 200360.18625865265 242586.8964927453 240082.83279669497 1.1848717170594159 1.0553321708902985 0.9011682848793029 0.905816295546334 1.00361676103079 0.9470489119550102 1.089112219325535 0.8345460769713596 1.0104299989586127 1.0 17.873172721301515 -4.9221825847680085 3.1947738981237306 0.9594190138287243 1.1887005536616557 0.5130721509564184 0.06753051075421927 0.21281383600090276 3.892591757853127 0.016783916245538832 0.10256369415379156 1.1962375070325284e-05 4.9221825847680085 0.22928153983293142 GNIETTSEDGQVFS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GNIETTSEDGQVFSPK 16 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 GNIETTSEDGQVFS(1)PK;GNIET(0.001)T(0.005)S(0.198)EDGQVFS(0.796)PK;GNIET(0.01)T(0.031)S(0.013)EDGQVFS(0.945)PK;GNIETTSEDGQVFS(0.999)PK 149.24 1.8761e-05 117215000.0 307342.0 313419.0 281650.0 368619.0 356911.0 307480.0 357962.0 371289.0 311173.0 270088.0 True False 359368.9303188015 344533.16700599005 288365.6041635736 347966.4725089221 286976.8516570518 291355.207512396 324053.24793954747 361543.0571632134 315723.31644352135 319052.8163845678 1.1263618807415225 1.0798624845571327 0.9038177673253771 1.0906234160600652 0.8994650318684118 0.9131880132385769 1.0156727391146185 1.1331761971579974 0.9895644239133333 1.0 18.283435743658295 -5.025942326000879 14.724405845687464 0.9957418443700432 1.1147496416244054 0.2761749162647036 0.07281036191041368 5.216784593577855 2965.4989916204677 0.019214062984827248 0.05243278369865103 9.42014687098896e-06 5.025942326000879 0.11900779725436217 GNIETTSEDGQVFS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 6 GNIETTSEDGQVFSPK 16 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 GNIETTSEDGQVFS(1)PK;GNIETTSEDGQVFS(1)PK;GNIETTSEDGQVFS(1)PK;GNIETTS(0.003)EDGQVFS(0.997)PK;GNIETTSEDGQVFS(1)PK;GNIET(0.013)T(0.039)S(0.239)EDGQVFS(0.71)PK 229.22 5.881699999999999e-29 197414000.0 649303.0 541943.0 481870.0 527710.0 580689.0 489504.0 486426.0 466610.0 502453.0 466687.0 True False 640043.8201524131 540688.164280378 442252.50867199054 566519.5537889535 546534.0146984998 468569.0550095573 511610.7581793022 488290.404043554 445861.4520753469 547353.2261286613 1.1693432861980864 0.9878231066702133 0.8079837435141641 1.0350163783556232 0.9985033221856466 0.8560633840119453 0.934699447736593 0.8920937718722353 0.8145771885348171 1.0 19.062112629425762 -4.82570604439513 3.5713348875419166 0.917935630533828 1.1867505569466845 0.5112085029581503 0.07416784011677834 0.20555772373006015 4.403168432526636 0.018772713547038303 0.1376832479913666 1.4938051611385726e-05 4.82570604439513 0.26881492641285654 GNIETTSEDGQVFS(ph)PKK ddPTM_PC-9_Lapatinib_30min_R1 2 GNIETTSEDGQVFSPKK 17 1 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 GNIETTSEDGQVFS(1)PKK;GNIETTSEDGQVFS(1)PKK 92.03399999999999 0.00096949 16103800.0 55446.0 54313.0 57612.0 56156.0 61144.0 58109.0 54050.0 47178.0 57292.0 47825.0 True False 54655.329872448914 54187.2415854808 52875.36374875121 60285.89957092444 57547.630133729195 55623.81352869506 56848.44453131888 49370.06211175655 50839.17164849403 56091.48752719319 0.974396156742179 0.9660510707477813 0.9426628902133715 1.0747780497298773 1.0259601353205345 0.9916622999475383 1.013495042429722 0.880170312613334 0.9063616225875124 1.0 15.77549422285883 -10.51182063930158 5.325059044662279 1.0000000946009568 0.9770997806469555 0.017586716303787386 0.054018100978168115 6.629981552655328e-08 1.2472162298141482e-08 0.0571412418116588 0.013858729594331954 3.077367484395394e-11 10.51182063930158 -0.022900313954001383 GNIWS(ph)AEK ddPTM_PC-9_AZD4547_30min_R2 1 GNIWSAEK 8 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 GNIWS(1)AEK 75.566 0.026189999999999998 6825500.0 47135.0 48398.0 53043.0 47154.0 55044.0 51059.0 59466.0 46437.0 50354.0 43094.0 True False 62122.94953109472 64041.70702552618 52339.615162319475 36283.3738220377 47402.090728601106 47866.27265844123 64758.35879909353 39261.2286661028 53015.60964027155 41585.29217679274 1.4938682952374038 1.5400085865277522 1.2586088114953378 0.8725049632400118 1.1398763420268696 1.151038507916356 1.5572418855153034 0.944113329760686 1.2748644259822626 1.0 15.343785747927933 -5.376210147125779 4.230191719715892 1.145582524417965 1.515555887417649 0.40870519524912674 0.18066082272204464 0.2202936987418255 6.518565350805711 0.04845063110438422 0.1077798308983028 4.205230957406918e-06 5.376210147125779 0.369973362999684 GNIWS(ph)AEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GNIWSAEK 8 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 GNIWS(1)AEK;GNIWS(1)AEK;GNIWS(1)AEK 104.79 0.0038524 35438800.0 236687.0 301251.0 238559.0 252843.0 230468.0 163289.0 255385.0 170641.0 144837.0 141203.0 True False 276753.43431866216 331157.20838149986 244247.15130004575 238677.02643806665 185309.44982838104 154725.83738614392 231193.0839727159 166161.8545590846 146954.9671203161 166801.98613766686 1.6591734950340997 1.9853313263799242 1.4642940228449137 1.4309003865282461 1.1109546961595493 0.9276018887355687 1.3860331601921398 0.9961623264002748 0.8810144922317029 1.0 17.347776941720007 -5.830418999777018 1.2706767425869914 1.048437323374112 1.8320170052592477 0.7759814384987398 0.1625849226027773 0.2166258981261298 0.7013794131087372 0.05753326668275294 0.13342941026355654 1.4776820582316574e-06 5.830418999777018 0.7835796818851357 GNIWS(ph)AEK ddPTM_PC-9_Lapatinib_30min_R1 2 GNIWSAEK 8 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 GNIWS(1)AEK;GNIWS(1)AEK 103.08 0.0040812 12909200.0 68062.0 110593.0 91573.0 96097.0 88362.0 80252.0 86786.0 76060.0 75384.0 64106.0 True False 67091.42339895782 110336.92870331359 84044.2214220023 103164.29395019448 83164.72088637615 76819.80903654921 91279.35443284069 79594.02527068146 66893.46009128794 75186.63668412436 0.892331754123059 1.467507173739708 1.1178079659965454 1.3721094399209586 1.10611040145032 1.021721577456459 1.2140369413826206 1.0586193076447017 0.8896987954431599 1.0 16.198188646469145 -7.609134244142401 0.8067397365062206 0.9526448742166117 1.2098845853713731 0.21658378384989818 0.1597364020235655 0.9054273927452265 1.0971591061026087 0.13578945406396425 0.06567138335830522 2.4596072009873172e-08 7.609134244142401 0.2572397111547614 GNKHDDGTQS(ph)DSENAGAHR ddPTM_PC-9_AZD4547_30min_R2 4 GNKHDDGTQSDSENAGAHR 19 1 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 GNKHDDGT(0.041)QS(0.956)DS(0.003)ENAGAHR;GNKHDDGT(0.003)QS(0.968)DS(0.029)ENAGAHR;GNKHDDGTQS(0.999)DSENAGAHR;GNKHDDGT(0.14)QS(0.783)DS(0.077)ENAGAHR 94.271 0.00032529 12633300.0 29638.6 31782.800000000003 43417.8 44315.5 40245.2 46885.6 37572.1 46765.0 43681.0 39266.700000000004 True False 39063.05827882261 42055.968553471095 42842.051603313426 34099.24614264987 34657.84866271885 43953.83602018477 40915.944113197846 39538.54380279297 45989.88848347107 37891.98478485328 1.0309055727911474 1.1098908856915382 1.1306362505571061 0.8999065722279215 0.9146485426800016 1.159977136847015 1.0798047224370613 1.0434540187664667 1.213710201368359 1.0 15.20960508984395 -6.78631623601865 24.999923517706755 1.1008810314840907 1.0221330683743153 0.1802828964787957 0.08728427383319354 466.2732227905312 468576.3142136232 0.032577832876212014 0.028743099087209612 1.6356250903781643e-07 6.78631623601865 -0.07874796310977539 GNKHDDGTQS(ph)DSENAGAHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GNKHDDGTQSDSENAGAHR 19 1 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 GNKHDDGT(0.001)QS(0.972)DS(0.027)ENAGAHR;GNKHDDGT(0.016)QS(0.967)DS(0.017)ENAGAHR;GNKHDDGT(0.002)QS(0.995)DS(0.004)ENAGAHR;GNKHDDGT(0.002)QS(0.959)DS(0.04)ENAGAHR 86.189 0.00052677 7721600.0 26903.5 30294.4 38618.3 33922.200000000004 36552.3 26145.100000000002 30679.899999999998 29310.3 23987.7 20668.699999999997 True False 31457.73118165394 33301.82782328527 39539.10673271831 32021.649111256254 29390.13920788105 24774.004930181924 27773.67776875907 28540.93568182989 24338.474732230126 24415.771696660828 1.2884184687046443 1.3639473794653691 1.6194084391002803 1.3115149301480251 1.2037358299799523 1.0146722060630216 1.1375302044029794 1.168954888521227 0.9968341379747881 1.0 14.575525756761007 -6.312754097047036 2.4471098993988165 1.0809922074954512 1.4197947320284148 0.7167827374021045 0.09848030774676439 0.16493055885978394 1.9419411844572174 0.0335657222268031 0.041152929245415984 4.866826935036367e-07 6.312754097047036 0.33880252453296356 GNKHDDGTQS(ph)DSENAGAHR ddPTM_PC-9_Lapatinib_30min_R1 4 GNKHDDGTQSDSENAGAHR 19 1 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 GNKHDDGT(0.014)QS(0.935)DS(0.05)ENAGAHR;GNKHDDGT(0.006)QS(0.96)DS(0.034)ENAGAHR;GNKHDDGT(0.119)QS(0.864)DS(0.017)ENAGAHR;GNKHDDGT(0.003)QS(0.952)DS(0.045)ENAGAHR 79.69 0.0011417999999999999 11144600.0 20536.7 30501.399999999998 41839.1 31634.8 36441.6 32415.899999999998 30888.4 34825.1 36342.2 28475.8 True False 20243.842892030465 30430.775882300433 38399.25070159647 33961.3287225992 34298.17673494218 31029.54752215365 32487.650213898058 36443.20128127802 32248.958735668144 33397.80408838155 0.6061429319861453 0.9111609793796807 1.1497537562643176 1.0168731043731614 1.0269590373120925 0.9290894527089052 0.9727480922974778 1.091185551745778 0.9656011709730022 1.0 15.027465627908981 -4.8137421541051175 3.421537357266899 1.0184040249455193 0.5686377868480903 0.8071265658524182 0.060663274532651607 0.11391533267560543 2.194887108941782 0.015585189685501119 0.12813161673046475 1.535528374017328e-05 4.8137421541051175 -0.449766238097429 GNKS(ph)PSPPDGS(ph)PAATPEIR ddPTM_PC-9_AZD4547_30min_R2 1 GNKSPSPPDGSPAATPEIR 19 1 O00499-6;O00499-11;O00499-2;O00499;O00499-7;O00499-8;O00499-4;O00499-3;O00499-5;O00499-9;O00499-10 O00499-6;O00499-9 BIN1 Myc box-dependent-interacting protein 1 2 GNKS(0.979)PS(0.024)PPDGS(0.954)PAAT(0.043)PEIR 72.30199999999999 0.018341999999999997 6688000.0 21091.0 17365.0 30787.0 40016.0 32923.0 29120.0 23161.0 28864.0 25115.0 28514.0 True False 27797.49927994736 22977.896658916936 30378.74426413155 30790.929441037057 28352.209742346735 27299.121796623687 25222.28413119775 24403.732028735496 26442.527626711308 27515.73353898614 1.010240168249994 0.835082104075485 1.1040499509522035 1.11902993236253 1.0303999238172379 0.9921277133297013 0.9166495269137973 0.8869010158918224 0.9609966454009216 1.0 14.747969169381589 -7.098994620662015 4.003083855006245 0.9321975943172437 1.0192018828368625 0.18481492383234543 0.07685308522095287 0.41111831124723497 11.673263380326963 0.03283598328401381 0.025340114696032055 7.961692120133978e-08 7.098994620662015 0.08700428851961883 GNKS(ph)PSPPDGS(ph)PAATPEIR ddPTM_PC-9_Lapatinib_30min_R1 1 GNKSPSPPDGSPAATPEIR 19 1 O00499-6;O00499-11;O00499-2;O00499;O00499-7;O00499-8;O00499-4;O00499-3;O00499-5;O00499-9;O00499-10 O00499-6;O00499-9 BIN1 Myc box-dependent-interacting protein 1 2 GNKS(0.965)PS(0.035)PPDGS(0.995)PAAT(0.005)PEIR 93.104 0.0026991 8684800.0 50000.0 56764.0 59364.0 55759.0 62055.0 61376.0 55073.0 52255.0 56587.0 55160.0 True False 49286.990831122996 56632.56644556979 54483.3210716668 59859.70286657122 58405.046904824085 58751.09155444402 57924.41046574144 54682.95806625627 50213.57617247311 64694.33250392005 0.7618440274986457 0.8753868268466675 0.8421652865552863 0.9252696573219009 0.9027845971095709 0.9081335146457241 0.8953552532941214 0.8452511363795715 0.7761665393089959 1.0 15.981351711139336 -3.9532577767965957 1.3885224973278345 0.8852989308762352 1.2984166774693024e-10 0.30774729451314187 0.055776596096731676 14.052237903734222 4.313741987891998 0.015750045879511974 30.20006895435278 0.00011136333369652604 3.9532577767965957 -0.8852989307463935 GNKS(ph)PSPPDGSPAATPEIR ddPTM_PC-9_AZD4547_30min_R2 3 GNKSPSPPDGSPAATPEIR 19 1 O00499-6;O00499-11;O00499-2;O00499;O00499-7;O00499-8;O00499-4;O00499-3;O00499-5;O00499-9;O00499-10 O00499-6;O00499-9 BIN1 Myc box-dependent-interacting protein 1 1 GNKS(0.618)PS(0.382)PPDGSPAATPEIR;GNKS(0.758)PS(0.239)PPDGS(0.002)PAATPEIR;GNKS(0.891)PS(0.108)PPDGSPAATPEIR 113.7 3.9614000000000004e-05 350990000.0 72705.0 70323.0 87880.0 123311.0 108771.0 96820.0 86588.0 100634.0 81472.0 96977.0 True False 95823.67764205442 93053.53450878286 86714.65378022799 94883.55408595868 93670.02417412757 90765.83009440622 94294.16425681743 85083.32763926583 85778.44359161555 93581.86474750168 1.023955633931868 0.9943543523080638 0.9266181435281026 1.013909632405479 1.0009420567421237 0.9699083293467858 1.00761151224372 0.9091860679292274 0.9166139595856423 1.0 16.513941356219135 -7.75693788608573 24.99879951631248 0.934675008192068 0.9891396744823688 0.29164953997699383 0.034431720069622807 124.78591715793554 693003.0780043645 0.01653983637134388 0.009132078244809905 1.7500969740983445e-08 7.75693788608573 0.05446466629030089 GNKS(ph)PSPPDGSPAATPEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GNKSPSPPDGSPAATPEIR 19 1 O00499-6;O00499-11;O00499-2;O00499;O00499-7;O00499-8;O00499-4;O00499-3;O00499-5;O00499-9;O00499-10 O00499-6;O00499-9 BIN1 Myc box-dependent-interacting protein 1 1 GNKS(0.859)PS(0.141)PPDGSPAATPEIR;GNKS(0.678)PS(0.322)PPDGSPAATPEIR 72.317 0.002684 150017000.0 25440.4 20874.8 24380.0 32574.0 30331.0 34658.0 28956.0 29299.0 26862.0 24161.3 True False 29746.957249196133 22947.112187252933 24961.31166166488 30748.984386332864 24387.85828290532 32840.47346807796 26213.078056714246 28529.932294856546 27254.805932088744 28541.55242925445 1.0422333306126044 0.8039896303514541 0.8745604053436175 1.0773409912635252 0.8544685277142918 1.150619734139521 0.9184180896147202 0.9995928695740462 0.9549167306033844 1.0 14.800776187421127 -5.732733310081495 24.930138425144758 0.9912154659141619 0.8966339189401162 0.14833778522205687 0.09410678933286735 350.329110926273 304244.8487199742 0.023959551526831012 0.04148983508870777 1.8504045596227374e-06 5.732733310081495 -0.09458154697404564 GNKS(ph)PSPPDGSPAATPEIR ddPTM_PC-9_Lapatinib_30min_R1 2 GNKSPSPPDGSPAATPEIR 19 1 O00499-6;O00499-11;O00499-2;O00499;O00499-7;O00499-8;O00499-4;O00499-3;O00499-5;O00499-9;O00499-10 O00499-6;O00499-9 BIN1 Myc box-dependent-interacting protein 1 1 GNKS(0.716)PS(0.283)PPDGSPAATPEIR;GNKS(0.827)PS(0.173)PPDGSPAATPEIR 103.94 0.00012676 196154000.0 73061.0 60628.0 73940.0 71398.0 63820.0 60804.0 54322.0 60121.0 71768.0 51406.0 True False 72019.13674225361 60487.61959097324 67860.9386166539 76648.84709674575 60066.233074947566 58203.554661046874 57134.52736041265 62914.44114250109 63684.732089456156 60291.45860581066 1.1945164109085378 1.0032535451902913 1.1255481321215495 1.2713052374115001 0.9962643874261589 0.9653698219773611 0.9476388311313179 1.0435050436221764 1.0562811642330787 1.0 15.879666011859529 -6.328517963831114 24.98822737939909 0.9991843896586022 1.1366196860683035 0.5146181653471491 0.06959545242453624 165.79808069743314 61762.73784178305 0.022473655239703096 0.025482732373596308 4.6933402073538395e-07 6.328517963831114 0.1374352964097013 GNKSPS(ph)PPDGSPAATPEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GNKSPSPPDGSPAATPEIR 19 1 O00499-6;O00499-11;O00499-2;O00499;O00499-7;O00499-8;O00499-4;O00499-3;O00499-5;O00499-9;O00499-10 O00499-6;O00499-9 BIN1 Myc box-dependent-interacting protein 1 1 GNKS(0.036)PS(0.964)PPDGSPAATPEIR;GNKS(0.291)PS(0.706)PPDGS(0.002)PAATPEIR;GNKS(0.108)PS(0.819)PPDGS(0.07)PAAT(0.002)PEIR 221.9 6.2061e-28 166575200.0 104727.5 97260.4 98270.1 129054.0 145009.8 134510.0 135072.8 128379.0 126057.2 93910.0 True False 122455.79728758968 106915.76974040909 100613.23187542982 121823.52277871345 116596.17065155896 127456.05880867818 122277.72654161355 125009.18727879439 127900.54807320767 110935.13960884913 1.1038503914932791 0.9637682894472202 0.9069554717304745 1.0981508943717575 1.0510300979713938 1.148924130425047 1.1022452125878033 1.1268673543799514 1.152930879468648 1.0 16.759356897731145 -5.8525299158689865 9.884878908544296 1.1032262606772714 0.9888941076819188 0.3722762059057827 0.0625066618982107 0.31125224524296824 31.002328889525558 0.017433565220780593 0.0258971805659459 1.4043329444087187e-06 5.8525299158689865 -0.1143321529953526 GNKSPS(ph)PPDGSPAATPEIR ddPTM_PC-9_Lapatinib_30min_R1 2 GNKSPSPPDGSPAATPEIR 19 1 O00499-6;O00499-11;O00499-2;O00499;O00499-7;O00499-8;O00499-4;O00499-3;O00499-5;O00499-9;O00499-10 O00499-6;O00499-9 BIN1 Myc box-dependent-interacting protein 1 1 GNKS(0.416)PS(0.583)PPDGSPAATPEIR;GNKS(0.295)PS(0.698)PPDGS(0.004)PAAT(0.004)PEIR 69.024 0.0037891999999999995 368460000.0 49069.0 48403.0 50572.0 45296.0 49268.0 40542.0 35943.0 37118.5 45613.0 36071.0 True False 48369.26706184748 48290.92582737148 46414.165373565316 48627.218943026455 46370.15310461485 38808.113168017946 37803.95266955033 38843.161017746315 40475.583613816205 42305.824288413714 1.1433240664948907 1.1414722828269512 1.0971105315699228 1.1494213801749273 1.0960701956424055 0.9173231776185086 0.8935874269185127 0.918151617917637 0.9567378557117783 1.0 15.368568673948626 -6.703228153435522 4.619259415720346 0.9288279704773554 1.1295061665894741 0.904175112975845 0.030716844422301107 0.05573730459763586 2.4058258432845796 0.010302578528367343 0.010070276354429043 1.980486318436077e-07 6.703228153435522 0.20067819611211868 GNKSPSPPDGS(ph)PAATPEIR ddPTM_PC-9_Lapatinib_30min_R1 1 GNKSPSPPDGSPAATPEIR 19 1 O00499-6;O00499-11;O00499-2;O00499;O00499-7;O00499-8;O00499-4;O00499-3;O00499-5;O00499-9;O00499-10 O00499-6;O00499-9 BIN1 Myc box-dependent-interacting protein 1 1 GNKSPS(0.007)PPDGS(0.681)PAAT(0.313)PEIR 125.84 0.00014331 25865000.0 20838.0 11539.0 12782.0 11019.0 14305.0 13411.0 10047.0 9493.3 13779.0 8283.8 True False 20540.846298778823 11512.282154454044 11731.113299946846 11829.374018306438 13463.608024712092 12837.442792567923 10567.184499651452 9934.393374995516 12227.063920697463 9715.643792530327 2.1142033134820393 1.1849222141413855 1.2074458008604712 1.2175594608976101 1.3857659165173706 1.3213167409902087 1.0876463490536585 1.0225151916987085 1.258492404805741 1.0 13.246093881658249 -4.7609875075347885 24.999997559707204 1.1968512447194524 2.114204348581439 0.8496042697360736 0.11693272704511891 4.146554363347728 229162.61181472035 0.03053860810344775 0.17475001498670797 1.733853871281314e-05 4.7609875075347885 0.9173531038619864 GNLELRPGGAHPGT(ph)CSPSRPGS ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GNLELRPGGAHPGTCSPSRPGS 22 2 Q5JTU8;B1AMJ5;A0A0A0MRG9;Q96SN8-4;Q96SN8-3;Q96SN8-2;Q96SN8 Q5JTU8 CDK5RAP2 CDK5 regulatory subunit-associated protein 2 1 GNLELRPGGAHPGT(0.825)CS(0.172)PS(0.002)RPGS 90.755 9.5251e-05 16514000.0 52493.0 52306.0 79881.0 71917.0 79939.0 71632.0 87023.0 67535.0 80327.0 46114.0 True False 61379.02811599082 57498.59400168873 81785.66599037948 67887.72364805994 64275.52679691305 67875.49181907099 78779.55144803987 65762.27780924749 81501.6304112462 54474.10316177685 1.1267561015866157 1.0555216270551488 1.5013678288101948 1.2462384822829924 1.1799281321994048 1.2460139383569981 1.4461835418213467 1.207220936046383 1.4961536891980243 1.0 15.733282919175023 -5.220518240870525 24.975749935955392 1.2962466780902784 1.0911387339414103 0.22227156424894134 0.14876075239982292 696.0384638430465 424817.0753399684 0.035546155720225875 0.09404459782373907 6.018409843513093e-06 5.220518240870525 -0.20510794414886813 GNLELRPGGAHPGTCS(ph)PSRPGS ddPTM_PC-9_AZD4547_30min_R2 1 GNLELRPGGAHPGTCSPSRPGS 22 2 Q5JTU8;B1AMJ5;A0A0A0MRG9;Q96SN8-4;Q96SN8-3;Q96SN8-2;Q96SN8 Q5JTU8 CDK5RAP2 CDK5 regulatory subunit-associated protein 2 1 GNLELRPGGAHPGT(0.157)CS(0.49)PS(0.335)RPGS(0.018) 91.541 0.0005563 29125000.0 17257.0 11570.0 20290.0 26006.0 21358.0 21545.0 14298.0 22739.0 17028.0 18260.0 True False 22744.367032101436 15309.776236318401 20020.94134274951 20010.718488694747 18392.81036591567 20197.787744102254 15570.494301103805 19225.210040237558 17928.065316649023 17620.72295791143 1.2907737716794174 0.8688506296187213 1.1362156587202015 1.1356354978448968 1.0438170107916933 1.146251932587917 0.8836467344895685 1.0910568247488246 1.0174420969827236 1.0 14.104985497133349 -7.224490218316979 24.992304303942205 1.005624300812815 1.0931432797829292 0.17650455654182884 0.10983077524885257 1172.4689187251145 793055.6610273246 0.03987576511891084 0.030886515875438166 5.963617516325265e-08 7.224490218316979 0.08751897897011429 GNLT(ph)PLTGR ddPTM_PC-9_Lapatinib_30min_R1 1 GNLTPLTGR 9 0 O75683 O75683 SURF6 Surfeit locus protein 6 1 GNLT(1)PLTGR 98.902 0.010546 5521400.0 17749.0 13426.0 19570.0 19050.0 24392.0 23127.0 16784.0 16304.0 18839.0 15705.0 True False 17495.896005232033 13394.912921890978 17961.030142384585 20451.000548937078 22957.310516517104 22137.91212167015 17652.993395257283 17061.543360678268 16717.153436535267 18419.588324402903 0.9498527164178185 0.7272102223992128 0.9751048626091819 1.1102854303124077 1.2463530732715926 1.2018679099543763 0.9583815384120171 0.9262716983785435 0.9075747591159683 1.0 14.16895319727732 -5.48814559851335 6.155111455326666 1.05695243115373 0.8395464664732741 0.33810621610281844 0.11701301874612711 0.22722605037017563 25.71559030147426 0.03480347274580547 0.07063698144886385 3.2497832917162526e-06 5.48814559851335 -0.2174059646804558 GNPS(ph)PPAAGEGQRPPPPLCVPGGGGGAPAR ddPTM_PC-9_AZD4547_30min_R2 2 GNPSPPAAGEGQRPPPPLCVPGGGGGAPAR 30 1 Q92623 Q92623 TTC9 Tetratricopeptide repeat protein 9A 1 GNPS(1)PPAAGEGQRPPPPLCVPGGGGGAPAR;GNPS(1)PPAAGEGQRPPPPLCVPGGGGGAPAR 82.381 2.0925e-07 26295000.0 11563.6 8891.7 13986.400000000001 21709.0 20821.2 17590.1 19516.4 23404.2 12785.3 10984.5 True False 15240.584262178141 11765.7681383295 13800.931197448592 16704.32545070654 17930.535780073213 16490.188266304613 21253.321791723476 19787.618665012884 13461.104856292734 10599.935998421593 1.4377996493985976 1.109984828217973 1.3019825024890386 1.5758892745384439 1.6915701927580693 1.5556875313926537 2.0050424639250886 1.8667677491599386 1.2699232201304977 1.0 13.371767933485232 -5.772074431238695 3.9408972377066975 1.6297108930990964 1.2582657358742255 0.15367037767516256 0.2805260874546171 0.2957183689965703 10.13710395779733 0.07774634986396486 0.12923638186815434 1.6901512414988577e-06 5.772074431238695 -0.3714451572248709 GNPS(ph)PPAAGEGQRPPPPLCVPGGGGGAPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GNPSPPAAGEGQRPPPPLCVPGGGGGAPAR 30 1 Q92623 Q92623 TTC9 Tetratricopeptide repeat protein 9A 1 GNPS(1)PPAAGEGQRPPPPLCVPGGGGGAPAR;GNPS(1)PPAAGEGQRPPPPLCVPGGGGGAPAR 77.83800000000001 5.6169e-05 9077600.0 7155.299999999999 6866.8 7294.8 10815.3 10643.4 10166.300000000001 13728.5 8783.7 10275.3 5471.5 True False 8366.550966383122 7548.4905228997795 7468.735697683057 10209.353804675693 8557.902174286193 9633.161331251684 12428.037094267216 8553.137182099448 10425.55682354223 6463.439637629832 1.2944425005029008 1.1678751479247729 1.1555357698709585 1.579554289520603 1.3240476671991337 1.4904078743410685 1.9228209422598748 1.3233104448448003 1.613004438510595 1.0 12.658086410496853 -5.75656578193946 24.98826579487936 1.4925010030990808 1.2021434828580995 0.20675210450969916 0.22775073667525364 165.82572107931355 850221.1236365427 0.060167084216066015 0.10013553054469208 1.7515971023055654e-06 5.75656578193946 -0.2903575202409814 GNPS(ph)PPAAGEGQRPPPPLCVPGGGGGAPAR ddPTM_PC-9_Lapatinib_30min_R1 2 GNPSPPAAGEGQRPPPPLCVPGGGGGAPAR 30 1 Q92623 Q92623 TTC9 Tetratricopeptide repeat protein 9A 1 GNPS(1)PPAAGEGQRPPPPLCVPGGGGGAPAR;GNPS(1)PPAAGEGQRPPPPLCVPGGGGGAPAR 74.63 1.2214e-06 20325700.0 15214.2 16890.1 16114.5 12360.8 18366.2 15265.0 16871.6 21189.0 18850.0 13403.199999999999 True False 14997.242718057427 16850.992011174658 14789.628013768857 13269.85446642002 17285.9362253385 14612.151534453013 17745.128894627196 22173.518294247533 16726.91450070013 15719.925261358609 0.9540276094646825 1.0719511531391528 0.9408205044157221 0.8441423381979337 1.0996194916924527 0.9295305983655895 1.1288303601701448 1.4105358597825273 1.0640581442086636 1.0 13.94030673802869 -7.40523356391444 5.030314209146747 1.193900113674465 0.9771561333926521 0.326294592593974 0.12161741985512263 0.22419369767732458 8.317006735501142 0.05058990893860995 0.03331493312233377 3.933384808181982e-08 7.40523356391444 -0.21674398028181285 GNPTVEVDLFT(ph)SK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GNPTVEVDLFTSK 13 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798 P06733 ENO1 Alpha-enolase;Enolase 1 GNPTVEVDLFT(0.797)S(0.203)K 81.703 0.027721 3195100.0 17130.0 18183.0 16672.0 22198.0 20583.0 19068.0 23664.0 16424.0 16422.0 15873.0 True False 20029.770667077955 19988.088072739363 17069.523708912086 20954.318026887 16549.908906301815 18068.040512704447 21422.37460747639 15992.887402666449 16662.140682628306 18750.649249401147 1.0682174468021506 1.0659944520789186 0.9103430756914855 1.1175249319730212 0.8826312457863495 0.9635954612761741 1.142487085249092 0.8529244609051191 0.8886167332664737 1.0 14.194652929967294 -1.5228787452804236 0.33553248487588555 0.9506454070701696 2.2972705701702645 0.13170911914903294 0.09278100671301813 126.33419765774038 1.7942854127885999 0.08346321166162364 106.09700326701993 0.02999999999999406 1.5228787452804236 1.3466251631000947 GNPTVEVDLFT(ph)SK ddPTM_PC-9_Lapatinib_30min_R1 1 GNPTVEVDLFTSK 13 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798 P06733 ENO1 Alpha-enolase;Enolase 1 GNPTVEVDLFT(0.5)S(0.5)K 106.58 0.0026968000000000005 2481500.0 19793.0 16195.0 18486.0 16498.0 18941.0 17497.0 21050.0 18284.0 16464.0 16594.0 True False 19510.74819040834 16157.50147251784 16966.152438023582 17711.317955714647 17826.92761943878 16748.69409749913 22139.866001558963 19133.541389023645 14609.650946394011 19462.250789884863 1.0024918700846606 0.8301969616440971 0.8717466762293198 0.9100344120999494 0.9159746121812379 0.8605733364716452 1.1375799356704281 0.9831104118218403 0.7506660511222628 1.0 14.24839094555901 GNPTVEVDLFTS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 GNPTVEVDLFTSK 13 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798 P06733 ENO1 Alpha-enolase;Enolase 1 GNPTVEVDLFT(0.09)S(0.91)K 66.533 0.037221 3802600.0 32698.0 38108.0 35332.0 44441.0 44639.0 41912.0 33140.0 34139.0 36129.0 36962.0 True False 43095.283839349424 50425.66575744354 34863.47459448132 34195.81405660555 38441.645375227534 39291.236014426264 36089.3957993132 28863.601986176604 38038.70518118467 35667.97163035719 1.2082347795373598 1.413751986797197 0.9774448335831029 0.9587260641281132 1.07776370839405 1.1015831351897032 1.0118151986135744 0.809230260843054 1.0664667331071256 1.0 15.122341554366502 -5.270724445667151 24.95314124671247 0.9988645673724446 1.3109933848843858 0.6567694827764515 0.08981369243023393 334.3516598196473 898554.4841370612 0.02396236917221017 0.05101952653539099 5.361367215592e-06 5.270724445667151 0.3121288175119412 GNPTVEVDLFTS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 GNPTVEVDLFTSK 13 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798 P06733 ENO1 Alpha-enolase;Enolase 1 GNPTVEVDLFT(0.018)S(0.982)K 121.24 0.0010639000000000002 0.0 28255.0 24372.0 23942.0 21365.0 26134.0 26379.0 22175.0 21422.0 22648.0 20435.0 True False 27852.078518667593 24315.568131411208 21973.581178792632 22936.25337155069 24596.849501420886 25250.831662452416 23323.112996891698 22417.34432485586 20097.14374598709 23967.162522074068 1.162093280463028 1.014536790035794 0.9168203018840748 0.9569865999125304 1.0262729048032644 1.0535594957974717 0.9731278358633738 0.9353357663515318 0.8385282875049292 1.0 14.548771497646014 -7.670618613734847 2.970834796120869 0.9124586387242987 1.0137654683273984 0.2680427268024548 0.07069704498975757 0.36568729790400134 6.445574661582852 0.041402607633151046 0.020691427399656116 2.1349189211639403e-08 7.670618613734847 0.10130682960309978 GNPTVEVDLFTSK ddPTM_PC-9_AZD4547_30min_R2 2 GNPTVEVDLFTSK 13 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798 P06733 ENO1 Alpha-enolase;Enolase 0 ; 174.39 0.00082916 10851600.0 39039.0 40524.0 47649.0 67774.0 61535.0 55510.0 47475.0 48801.0 49155.0 53876.0 False True 51452.58993835589 53622.59050998848 47017.143126696494 52149.75139786204 52991.927421416854 52038.950924813915 51700.18302873855 41259.926785418545 51753.23294807859 51989.81763857812 0.9896666746562391 1.0314056279781751 0.90435291490248 1.003076251592105 1.0192751163276852 1.0009450559449422 0.9944290127760586 0.7936155320306866 0.9954494033400114 1.0 15.665941474326672 GNPTVEVDLFTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GNPTVEVDLFTSK 13 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798 P06733 ENO1 Alpha-enolase;Enolase 0 128.21 0.00049602 7506000.0 26350.0 26790.0 36251.0 31477.0 37739.0 36961.0 36576.0 32350.0 35710.0 26770.0 False True 30810.534563777233 29449.534151057996 37115.3613226831 29713.4457398109 30344.31386167827 35022.70009387816 33111.25649269168 31500.84677765829 36232.19119331731 31623.189088796604 0.9743019427061114 0.9312638920876994 1.1736754701894456 0.9396094004427187 0.9595589419040785 1.1075005748324709 1.047056209281001 0.9961312468899078 1.145747542778776 1.0 14.948695245366938 -6.7555933507362695 24.999186262107088 1.0582808860084052 0.9988765442861585 0.14725117124058273 0.0763195601533201 315.6962211352889 1350000.2457504952 0.025524604798038086 0.02486585936547817 1.7555235073503167e-07 6.7555933507362695 -0.059404341722246734 GNPTVEVDLFTSK ddPTM_PC-9_Lapatinib_30min_R1 2 GNPTVEVDLFTSK 13 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798 P06733 ENO1 Alpha-enolase;Enolase 0 ; 131.06 0.00033604 97128000.0 100353.0 91809.0 93271.0 85172.0 95981.0 82274.0 102984.0 79865.0 81884.0 87218.0 False True 98921.9478175139 91596.42190122834 85602.61841647179 91435.83300546283 90335.58628590636 78755.33281006143 108316.00761541809 83575.81946151683 72661.3616432535 102293.51508932005 0.9670402638049715 0.8954274552130574 0.8368332864671411 0.8938575717690748 0.8831017900502067 0.76989565507935 1.0588746268112827 0.817019723963348 0.7103222680324113 1.0 16.64235516257942 -4.818351088415873 3.3753321870338078 0.8688255755069914 0.9758451717795859 0.08130548788981695 0.09635062529785575 0.7419017785602496 13.828037155037334 0.023876648190061318 0.19579364696590404 1.5193187991818767e-05 4.818351088415873 0.1070195962725945 GNRGS(ph)GGGGGGGGQGSTNYGK ddPTM_PC-9_AZD4547_30min_R2 4 GNRGSGGGGGGGGQGSTNYGK 21 1 Q99729-3;Q99729-4 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 1 GNRGS(1)GGGGGGGGQGSTNYGK;GNRGS(1)GGGGGGGGQGSTNYGK;GNRGS(1)GGGGGGGGQGSTNYGK;GNRGS(1)GGGGGGGGQGSTNYGK 148.9 4.5148e-06 45084900.0 45453.100000000006 38235.9 57289.0 88846.0 77946.0 57972.0 45306.8 70076.0 46366.6 62650.0 True False 59906.24031678795 50594.906931222686 56529.31042803239 68363.92735701666 67124.54334589688 54347.00167561361 49339.017429098494 59247.36438628291 48817.443816709994 60456.642569175885 0.9908959176527518 0.8368792043542747 0.9350388646433723 1.1307926548979803 1.1102922771321848 0.898941776553809 0.8161058128996107 0.9799975961035334 0.8074785787327166 1.0 15.88361324135835 -6.9506420512766 24.999251197258157 0.893270408404256 0.9961822355988231 0.21141817217632275 0.09618336807971022 190.19317768568905 96329.98653618219 0.03636842723394871 0.03207393573266066 1.1203609127799923e-07 6.9506420512766 0.10291182719456715 GNRGS(ph)GGGGGGGGQGSTNYGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GNRGSGGGGGGGGQGSTNYGK 21 1 Q99729-3;Q99729-4 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 1 GNRGS(1)GGGGGGGGQGSTNYGK;GNRGS(1)GGGGGGGGQGSTNYGK;GNRGS(1)GGGGGGGGQGSTNYGK;GNRGS(1)GGGGGGGGQGSTNYGK;GNRGS(1)GGGGGGGGQGSTNYGK 159.81 8.809399999999999e-07 23461800.0 60161.5 42518.3 65278.1 85052.8 96132.0 91556.90000000001 91220.0 85658.1 83087.9 62596.5 True False 70345.65370621199 46739.23583034454 66834.5774725729 80287.56736089806 77295.62468933615 86755.49498728914 82578.98122439122 83409.66563725912 84302.90335063648 73944.74993637859 0.9513272242686164 0.6320832225487079 0.9038447966904585 1.0857777926083565 1.0453159251446604 1.1732475268620532 1.1167659812960546 1.1279998337816284 1.1400796327416072 1.0 16.174160099427823 -5.654372118261806 3.2340301547116614 1.1074325051846226 0.7860352768740639 0.682699799754854 0.08597038653743987 0.11907573877626085 2.4506747805068083 0.02274715985304137 0.042526313720738035 2.2162966078002678e-06 5.654372118261806 -0.3213972283105586 GNRGS(ph)GGGGGGGGQGSTNYGK ddPTM_PC-9_Lapatinib_30min_R1 5 GNRGSGGGGGGGGQGSTNYGK 21 1 Q99729-3;Q99729-4 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 1 GNRGS(0.996)GGGGGGGGQGS(0.004)TNYGK;GNRGS(0.999)GGGGGGGGQGSTNYGK;GNRGS(1)GGGGGGGGQGSTNYGK;GNRGS(1)GGGGGGGGQGSTNYGK;GNRGS(0.999)GGGGGGGGQGSTNYGK 131.62 1.3744000000000001e-05 31917900.0 52665.2 40359.4 48015.5 40504.6 34484.5 40151.899999999994 32749.5 31887.800000000003 42338.799999999996 28781.100000000006 True False 51914.18459038514 40265.950288974156 44067.850935189956 43483.443403384605 32456.189509135555 38434.69683565042 34445.108865465794 33369.42360013718 37570.15849667071 33755.87478659488 1.5379303578588128 1.192857555715444 1.3054868586220185 1.2881740934959485 0.9614975086358758 1.1386076372967704 1.0204181963355492 0.9885515872747825 1.1129961446471106 1.0 15.042850986540014 -1.5228787452884713 0.3301325653466078 1.0026728867973183 6.028280831262156 0.7195329579783334 0.091386033269102 31.23538298473085 0.44463132599955413 0.082396328298091 95.79039781139289 0.02999999999943814 1.5228787452884713 5.025607944464838 GNS(ph)PEMR ddPTM_PC-9_AZD4547_30min_R2 1 GNSPEMR 7 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 GNS(1)PEMR 92.23899999999999 0.014719999999999999 14367000.0 107660.0 89219.0 124000.0 129410.0 118770.0 147740.0 118750.0 124400.0 119530.0 134380.0 True False 141893.64053288766 118057.29697736319 122355.67897983927 99576.52386456916 102280.83561943074 138501.7944448208 129318.51995076763 105176.83842761558 125848.1117746687 129675.39710208845 1.094221754502747 0.9104062884374375 0.9435535322364454 0.7678906414774762 0.7887451120655445 1.0680653195592968 0.9972479193486498 0.8110778202962734 0.970485647910477 1.0 16.98454526207791 -8.51288909158307 24.36848416129462 1.0000000433526215 0.9187842954060224 0.05590936323748763 0.10544341676243947 1222.61407534738 2982408.515863591 0.1055572230552046 0.027254757866868096 3.0698058432422844e-09 8.51288909158307 -0.08121574794659914 GNS(ph)PEMR ddPTM_PC-9_Lapatinib_30min_R1 2 GNSPEMR 7 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 GNS(1)PEMR;GNS(1)PEMR 96.665 0.012731999999999999 36891000.0 202747.0 278637.0 315800.0 263200.0 317290.0 282592.0 312360.0 283210.0 322180.0 252585.0 True False 199855.79060075406 277991.8331459062 289836.14302325284 282556.60600946145 298627.62601614126 270506.1989141268 328532.47241078183 296368.97050893615 285892.69569419476 296243.98070164345 0.674632409838008 0.938388123490281 0.9783697286837225 0.953796952566719 1.0080462236189651 0.9131196464260383 1.108992903864795 1.0004219150951073 0.9650582436040319 1.0 18.17642631502961 -4.313079186335089 1.5186296716845615 0.9943547616173387 1.9656603103448238e-11 0.7943838482648589 0.047965431227136666 1.7444891329808883 1.4314770044489404 0.013426472604416909 3.698667642779068 4.8631852555770395e-05 4.313079186335089 -0.9943547615976821 GNS(ph)PNSEPPTPK ddPTM_PC-9_AZD4547_30min_R2 1 GNSPNSEPPTPK 12 0 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 GNS(0.995)PNS(0.004)EPPT(0.001)PK 191.01 0.00012958 8313900.0 39009.0 31478.0 38992.0 54225.0 43407.0 39596.0 35964.0 46905.0 35943.0 34657.0 True False 51413.05056239464 41652.647914159956 38474.94060307981 41724.26401789868 37380.68730935956 37120.05586054645 39164.72632850033 39656.91001967292 37842.873600911196 33443.6689787698 1.5373029375165712 1.245456888734345 1.1504401812942202 1.2475982836807002 1.117720885620803 1.10992773801554 1.1710654818812578 1.1857822789971793 1.131540729724781 1.0 15.02944550828153 GNS(ph)PNSEPPTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GNSPNSEPPTPK 12 0 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 GNS(0.903)PNS(0.097)EPPTPK;GNS(0.922)PNS(0.078)EPPTPK;GNS(0.81)PNS(0.183)EPPT(0.007)PK;GNS(0.748)PNS(0.252)EPPT(0.001)PK 180.3 8.4108e-26 7329100.0 87691.0 92429.0 87783.0 104310.0 112326.0 96789.0 88024.0 89396.0 83502.0 74828.0 True False 102535.35432380238 101604.74027801967 89876.07963888157 98465.84887758302 90316.52663893794 91713.21445270353 79685.72948142771 87049.4497228915 84723.05877973636 88393.72406187808 1.159984551075422 1.149456495428267 1.0167699188232617 1.1139461531075914 1.0217527047023593 1.0375534623759228 0.9014862800174079 0.9847921970337448 0.9584736889287281 1.0 16.43165632172019 -5.699003293835219 0.5413774440688 0.9582349844433823 1.1989053856187988 0.693862091812304 0.043879279755062506 0.985509696722337 0.43306823479666967 0.0301430248562037 0.134620431744092 1.999846702066143e-06 5.699003293835219 0.2406704011754165 GNS(ph)PNSEPPTPK ddPTM_PC-9_Lapatinib_30min_R1 2 GNSPNSEPPTPK 12 0 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 GNS(0.921)PNS(0.079)EPPTPK;GNS(0.976)PNS(0.024)EPPTPK 186.29 0.000384 28120000.0 72877.0 64358.0 74706.0 61558.0 68910.0 65196.0 55759.0 60264.0 69314.0 52480.0 True False 71837.760615995 64208.98300514373 68563.9610534993 66085.18067146814 64856.84928227263 62407.719059298935 58645.928189117614 63064.08544454824 61507.12741122176 61551.098074795555 1.1671239484419809 1.0431817630145017 1.1139356274388779 1.0736637158148319 1.0537074286385597 1.0139172331818098 0.952800681441172 1.024580997205186 0.9992856234096691 1.0 15.909496974243439 -6.486856226970406 1.4913583139752553 0.9946074611779304 1.101540938090404 0.6805222960800321 0.03322804109217349 0.2352468605183294 1.0661071335426582 0.01293204950261511 0.014725938316656171 3.2594458697967426e-07 6.486856226970406 0.10693347691247357 GNS(ph)PPAALGPQDPAPA ddPTM_PC-9_AZD4547_30min_R2 3 GNSPPAALGPQDPAPA 16 0 Q9ULV8-2;Q9ULV8 Q9ULV8-2 CBLC E3 ubiquitin-protein ligase CBL-C 1 GNS(1)PPAALGPQDPAPA;GNS(1)PPAALGPQDPAPA;GNS(1)PPAALGPQDPAPA 133.52 3.5336e-05 2835200.0 29901.9 32904.4 45652.0 45143.0 43950.0 41728.0 41093.9 45330.0 36700.0 36599.8 True False 39410.08220184238 43540.103819387645 45046.62465151313 34735.97880239741 37848.30113222181 39118.741563513504 44751.1774905672 38325.29007977345 38639.88707546503 35318.45214211212 1.1158496426532687 1.2327862966415906 1.27544164365577 0.9835079595965591 1.0716296676856123 1.1076006787078332 1.2670764084026187 1.0851350428824742 1.0940424829488091 1.0 15.108134496719535 -14.52287874390756 0.12027854782655122 0.5500799267832451 1.2054745782015024 0.20175780785235242 0.08746404063096155 277.17340374923197 2.1516768170689247 30.347637211367157 0.900124905638337 3.000000009482812e-15 14.52287874390756 0.6553946514182573 GNS(ph)PPAALGPQDPAPA ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GNSPPAALGPQDPAPA 16 0 Q9ULV8-2;Q9ULV8 Q9ULV8-2 CBLC E3 ubiquitin-protein ligase CBL-C 1 GNS(1)PPAALGPQDPAPA 127.61 0.00013963 0.0 11349.0 12706.0 18976.0 13223.0 17266.0 12110.0 14851.0 11708.0 11076.0 12225.0 True False 13270.161547032552 13967.36770897138 19428.459806880754 12482.158179544418 13882.851245018075 11474.930281563393 13444.205768070993 11400.677405651415 11237.965546266658 14441.295726953247 0.9189038018427329 0.9671824449175065 1.3453404856615088 0.8643378278202355 0.9613300293482052 0.7945914617721298 0.9309556443040437 0.7894497572245668 0.7781826339372103 1.0 13.817912571565756 GNS(ph)PPAALGPQDPAPA ddPTM_PC-9_Lapatinib_30min_R1 2 GNSPPAALGPQDPAPA 16 0 Q9ULV8-2;Q9ULV8 Q9ULV8-2 CBLC E3 ubiquitin-protein ligase CBL-C 1 GNS(1)PPAALGPQDPAPA;GNS(1)PPAALGPQDPAPA 148.44 7.2489999999999995e-06 5061800.0 19668.3 24406.0 27570.0 25043.0 28546.0 29172.0 26327.0 27770.0 27758.0 18249.3 True False 19387.826435275532 24349.489406500175 25303.30102327763 26884.745760999005 26866.98040359532 27924.381563253384 27690.083240999676 29060.295579369194 24631.601735301556 21403.667189336265 0.9058179733300532 1.1376316586828437 1.1821946584875063 1.2560812837901685 1.2552512691367668 1.3046540724182942 1.293707428547358 1.3577250721711658 1.150812219112317 1.0 14.385570380970684 -4.236857202304712 1.067267868870079 1.252425876964658 0.2075653167627414 0.49642733052122956 0.09561317833950185 3.555758936235509 1.4815435846107858 0.02802744190642516 5.577478271646944 5.796192461348919e-05 4.236857202304712 -1.0448605602019165 GNS(ph)PPSSGEACR ddPTM_PC-9_AZD4547_30min_R2 2 GNSPPSSGEACR 12 0 P41227-2;P41227 P41227-2 NAA10 N-alpha-acetyltransferase 10 1 GNS(0.964)PPS(0.01)S(0.025)GEACR;GNS(0.953)PPS(0.015)S(0.032)GEACR 148.85 6.2494e-05 184739000.0 206127.0 241521.0 277131.0 243136.0 260674.0 267156.0 246689.0 326843.0 263346.0 247531.0 True False 271671.0982920538 319587.9400494257 273456.0618658212 187084.75161375414 224483.9146607692 250450.69308718378 268643.8431000837 276336.92445496103 277265.9319284852 238865.0150325727 1.137341515897619 1.3379436917785774 1.1448142032374709 0.7832237449600664 0.9397940281466399 1.0485030344566415 1.1246680183092121 1.1568748333332886 1.160764090508089 1.0 17.86583604177217 -5.526048360649958 24.999927788421804 1.0322831184620753 1.2385767285731963 0.3483915993782494 0.11514246642473298 104.8750306354905 827185.0592189585 0.034338661680861936 0.05987410369581549 2.978184776652515e-06 5.526048360649958 0.20629361011112102 GNS(ph)PPSSGEACR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GNSPPSSGEACR 12 0 P41227-2;P41227 P41227-2 NAA10 N-alpha-acetyltransferase 10 1 GNS(1)PPSSGEACR;GNS(0.642)PPS(0.179)S(0.179)GEACR;GNS(0.992)PPS(0.004)S(0.004)GEACR 173.33 0.0010464 189902400.0 144400.0 214848.0 194079.0 155960.0 177294.0 138837.0 167417.0 121273.8 125426.0 116506.2 True False 168844.06796999744 236176.6895590338 198706.57940870654 147222.0668291422 142554.5134156282 131556.14331143006 151558.04976588418 118090.49125021273 127260.11796732026 137627.85179742821 1.2268161259867354 1.7160530116146675 1.4437962724374929 1.069711289585741 1.0357969811622973 0.9558831413358468 1.101216416492205 0.8580421020014746 0.9246683451444986 1.0 17.070412932732403 -5.79207327193135 3.4434147856154484 0.9824179519043738 1.498693764525613 0.7480317590172886 0.12577925353907402 0.10463837250315702 2.573737535382455 0.035136142667840806 0.05859565777582227 1.6140862135284757e-06 5.79207327193135 0.5162758126212393 GNS(ph)PPSSGEACR ddPTM_PC-9_Lapatinib_30min_R1 3 GNSPPSSGEACR 12 0 P41227-2;P41227 P41227-2 NAA10 N-alpha-acetyltransferase 10 1 GNS(0.952)PPS(0.036)S(0.011)GEACR;GNS(0.999)PPS(0.001)SGEACR;GNS(0.995)PPS(0.002)S(0.003)GEACR 145.49 7.3014e-05 183632000.0 158746.9 214454.0 203783.6 181634.7 217670.5 220506.7 192455.7 205806.0 223952.0 166718.2 True False 156483.1400953842 213957.4449390144 187029.29903544433 194992.7217535968 204867.54914666826 211076.14246722378 202420.1144530277 215368.49809174126 198728.16744089103 195535.2187319625 0.8002811008173907 1.0942143636656314 0.9564992958727401 0.9972255791980403 1.047727107552417 1.079478898154734 1.0352105148408224 1.1014307268449988 1.0163292767903127 1.0 17.577068955697698 -4.752979484153331 24.997329961942857 1.0375599828813715 0.8002806573138753 0.7231533447933809 0.04383433465606276 172.45554969960315 509533.54286359396 0.01107239130702337 0.12519018719638114 1.7661212493698102e-05 4.752979484153331 -0.2372793255674962 GNS(ph)PPSSGEACREEK ddPTM_PC-9_AZD4547_30min_R2 2 GNSPPSSGEACREEK 15 1 P41227-2;P41227 P41227-2 NAA10 N-alpha-acetyltransferase 10 1 GNS(0.997)PPS(0.003)SGEACREEK;GNS(0.661)PPS(0.169)S(0.169)GEACREEK 149.6 0.00064987 144833000.0 47200.0 43425.0 62376.0 90351.0 76248.0 62792.0 51756.0 59148.0 49203.0 67204.0 True False 62208.6181790107 57461.2820278415 61548.85348424559 69521.97285903487 65662.28133628328 58865.606313653676 56362.183735342645 50008.035685824856 51803.77013008464 64851.20841530567 0.9592514881238313 0.8860479770841084 0.949077973845732 1.072022781962947 1.012506673981825 0.9077025355746599 0.8690999768948097 0.7711195659697585 0.7988096351009293 1.0 15.984845836964373 -7.105149325546427 2.755981743507732 0.8392583908664065 0.973898265895314 0.3468304070231858 0.07279812362187357 0.2913794681655279 4.29476896662801 0.031880941769476936 0.023963261589396597 7.849656897014745e-08 7.105149325546427 0.1346398750289075 GNS(ph)PPSSGEACREEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GNSPPSSGEACREEK 15 1 P41227-2;P41227 P41227-2 NAA10 N-alpha-acetyltransferase 10 1 GNS(0.711)PPS(0.24)S(0.049)GEACREEK 54.253 0.035406 112200000.0 20145.0 13199.0 19751.0 28346.0 28108.0 24262.0 22252.0 28544.0 25386.0 17640.0 True False 23555.150618113566 14509.309490847887 20221.938746084626 26757.865518971932 22600.439174966286 22989.658009190014 20144.129469471114 27794.750244867937 25757.22222440641 20837.992361836834 1.130394435754425 0.6962911416274709 0.9704360379323076 1.2840903794540632 1.0845785324481276 1.1032568593937 0.9667020277041432 1.3338497184484943 1.236070240220395 1.0 14.34692866728368 -5.568638706683854 8.187085760181295 1.1455029906188756 0.8935123520558719 0.3059543597542451 0.1471589052327664 0.2549839905738041 40.581957354479925 0.03914172371035252 0.06822430910288803 2.699984638863787e-06 5.568638706683854 -0.25199063856300374 GNS(ph)RPGTPS(ph)AEGGSTSSTLR ddPTM_PC-9_AZD4547_30min_R2 1 GNSRPGTPSAEGGSTSSTLR 20 1 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 2 GNS(0.855)RPGT(0.238)PS(0.87)AEGGS(0.024)T(0.006)S(0.006)S(0.001)TLR 134.83 0.0022723 4048800.0 16460.0 19899.0 24450.0 20970.0 23599.0 22281.0 24058.0 28755.0 22189.0 18374.0 True False 21693.93761073127 26330.962603846136 24125.7770246538 16135.69048327037 20322.68619839142 20887.765547753184 26199.11539347849 24311.57547416469 23361.8652402587 17730.731852610345 1.2235218371732048 1.4850465746550474 1.360675759196142 0.9100408611105835 1.1461842842882701 1.178054336469933 1.4776104907153855 1.3711546526256615 1.317591706561133 1.0 14.113964465607873 GNS(ph)RPGTPS(ph)AEGGSTSSTLR ddPTM_PC-9_Lapatinib_30min_R1 1 GNSRPGTPSAEGGSTSSTLR 20 1 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 2 GNS(0.832)RPGT(0.177)PS(0.99)AEGGSTSSTLR 117.55 0.00048042 8980200.0 23747.0 36054.0 31746.0 27571.0 29705.0 32421.0 30511.0 33611.0 33155.0 28492.0 True False 23408.363425333548 35970.519178151146 29135.96642310381 29598.663314159796 27957.810302277012 31034.429407042324 32090.710288530423 35172.68976298807 29420.734762372034 33416.80423679641 0.70049676981253 1.0764200826404207 0.8718956551512841 0.8857418891531128 0.8366392580261068 0.9287072811369925 0.9603165539448629 1.0525449864609793 0.8804173658825172 1.0 15.028286149687684 -7.1220569390025075 3.1622295346218516 0.9781501039367375 0.8858814443015974 0.1894236592563735 0.09456238457422145 0.4731765032735621 8.934831922265518 0.03738164483227644 0.028200484832681255 7.549932363548348e-08 7.1220569390025075 -0.09226865963514008 GNS(ph)RPGTPSAEGGSTSSTLR ddPTM_PC-9_AZD4547_30min_R2 3 GNSRPGTPSAEGGSTSSTLR 20 1 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 GNS(0.96)RPGT(0.035)PS(0.004)AEGGSTSSTLR;GNS(0.997)RPGT(0.003)PSAEGGSTSSTLR;GNS(0.896)RPGT(0.104)PSAEGGSTSSTLR 166.38 2.0561e-07 27386200.0 24996.0 21688.9 40509.4 36446.7 37128.7 34676.1 30980.4 49442.6 28161.7 26570.1 True False 32944.20805090151 28699.412775443896 39972.21888762822 28044.476410901756 31974.020893013076 32507.797985298854 33737.59558301277 41802.38224791981 29650.269968749955 25639.888886309007 1.2848810771755257 1.1193267218396017 1.558985651804922 1.0937830711847092 1.2470421004861032 1.267860330028853 1.3158245627588392 1.6303651873562186 1.1564117964872453 1.0 14.646102389418806 -7.2730047849528034 5.736894513681702 1.3286386585916714 1.2604706421935779 0.0 0.19142627311312838 0.8210676123922058 105.52202347722105 0.0758989662095266 0.05334805733484729 5.333290193635826e-08 7.2730047849528034 -0.06816801639809356 GNS(ph)RPGTPSAEGGSTSSTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GNSRPGTPSAEGGSTSSTLR 20 1 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 GNS(0.991)RPGT(0.008)PS(0.001)AEGGSTSSTLR;GNS(0.963)RPGT(0.036)PS(0.001)AEGGSTSSTLR;GNS(0.999)RPGT(0.001)PSAEGGSTSSTLR 102.79 0.0010186 26442300.0 12375.3 16907.7 26337.800000000003 22767.7 24643.300000000003 24126.8 21230.800000000003 16814.699999999997 20500.7 16854.5 True False 14470.193866683585 18586.184716903463 26965.79303866273 21492.099582879335 19814.62226840925 22861.548135196004 19219.664926318863 16373.33194164732 20800.483953985997 19910.087429851406 0.726777012791429 0.9335059317236848 1.3543784342319176 1.079457820494349 0.9952051862264037 1.1482394648312515 0.965322979822912 0.8223636384990761 1.0447208746456638 1.0 14.281211935833184 -7.5015742802818695 23.621733381398883 0.9388940270515845 1.0495334073502762 0.054514797832269646 0.1589550441792523 996.4955472578773 1104889.689194477 0.0704268008341609 0.04686573620625454 3.150835425717229e-08 7.5015742802818695 0.11063938029869169 GNS(ph)RPGTPSAEGGSTSSTLR ddPTM_PC-9_Lapatinib_30min_R1 2 GNSRPGTPSAEGGSTSSTLR 20 1 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 GNS(0.999)RPGT(0.001)PSAEGGSTSSTLR;GNS(0.886)RPGT(0.103)PS(0.002)AEGGS(0.002)T(0.002)S(0.002)S(0.002)TLR 149.82 0.00052963 9008400.0 15420.6 20226.2 19696.4 18220.8 22303.0 23754.0 22564.6 26825.0 21855.8 21003.2 True False 15200.699416208305 20179.36747659402 18077.0380223027 19560.81841480696 20991.181389385096 22738.096793278542 23732.884578564244 28071.387429477105 19394.169652222907 24633.575134995164 0.6170724035348711 0.8191814369618899 0.7338373712803847 0.794071437361859 0.8521370233249018 0.9230530553795315 0.9634364662256688 1.1395579925220878 0.7873063307270812 1.0 14.588338404675211 -6.445130167587111 1.0342320193794956 0.9859324334709211 0.7201251108790512 0.5751997767156651 0.09185736921584742 0.36670685498057626 0.8370344046802655 0.04271227899298948 0.05383157095288718 3.588143739843591e-07 6.445130167587111 -0.2658073225918699 GNS(ph)SDHEGCWNEESWTFSQSGTSGSK ddPTM_PC-9_Lapatinib_30min_R1 1 GNSSDHEGCWNEESWTFSQSGTSGSK 26 0 C9JA69;Q8WY36-2;Q8WY36 C9JA69 BBX HMG box transcription factor BBX 1 GNS(0.405)S(0.405)DHEGCWNEES(0.19)WT(0.001)FSQSGTSGSK 66.925 0.00023665 4784600.0 7716.6 13491.0 19705.0 12377.0 24207.0 15019.0 15731.0 18539.0 21549.0 15277.0 True False 7606.5598689488725 13459.762418384567 18084.93096349967 13287.245868461632 22783.191852793123 14376.672380999002 16545.474207625844 19400.389619946916 19121.92469897014 17917.609094677064 0.424529848193229 0.7512030398287444 1.0093384037981004 0.7415747155913223 1.2715531258889625 0.8023767180672561 0.9234197554037022 1.0827554902796912 1.0672140796201905 1.0 14.129090518207194 -4.617580481016314 1.2332674666763295 0.9943807282726009 2.852688285596601e-14 0.6115433983426654 0.1399512316596258 1.3614768418995353 1.3809908152448833 0.040728857557828284 1.9029145132133825 2.412234469413835e-05 4.617580481016314 -0.9943807282725724 GNSPPS(ph)SGEACR ddPTM_PC-9_AZD4547_30min_R2 1 GNSPPSSGEACR 12 0 P41227-2;P41227 P41227-2 NAA10 N-alpha-acetyltransferase 10 1 GNS(0.213)PPS(0.393)S(0.393)GEACR 92.65 0.020087 0.0 4119.9 4936.7 5884.9 7927.1 5999.6 6265.8 5767.2 8036.5 6510.2 4837.9 True False 5429.942500756487 6532.3917325698385 5806.86238087465 6099.629567474128 5166.659100634314 5873.998535483676 6280.4696274532 6794.643585398174 6854.315881163283 4668.526593542152 1.1630955488756518 1.3992405530271417 1.24383191667091 1.306542748607576 1.1067001541302592 1.2582125040497834 1.3452787515745985 1.4554149899878523 1.468196816238484 1.0 12.188751585862377 -7.264825219961361 5.549366477773507 1.355907049461963 1.2491705769591017 0.029473600465914407 0.14241129721901183 0.38980721573477806 45.7492227395751 0.05613618423617371 0.0399604160466249 5.4346900436632625e-08 7.264825219961361 -0.10673647250286122 GNSPPS(ph)SGEACR ddPTM_PC-9_Lapatinib_30min_R1 1 GNSPPSSGEACR 12 0 P41227-2;P41227 P41227-2 NAA10 N-alpha-acetyltransferase 10 1 GNS(0.131)PPS(0.434)S(0.434)GEACR 92.65 0.0057459 3906700.0 4526.9 5073.6 5637.5 5275.5 6171.3 5960.7 4190.3 6581.5 7496.2 4159.6 True False 4462.345575868209 5061.852390921054 5174.006511379312 5663.4778685521 5808.316267242624 5705.774756070359 4407.253230704637 6887.300516947011 6651.899017514497 4878.581317681394 0.914680987215561 1.037566468878039 1.060555553850709 1.160886228958819 1.19057485957887 1.169556144404312 0.90338828928227 1.4117424858709307 1.363490446168456 1.0 12.252245960419748 -3.4210417130296347 0.4729529306874334 1.1992852533416953 8.400853341137722e-09 0.2531372525285136 0.14129263432644926 22.820000473611884 1.4412677559357014 0.08951102539060204 20.151041201407693 0.000379278554353353 3.4210417130296347 -1.199285244940842 GNSPPS(ph)SGEACREEK ddPTM_PC-9_AZD4547_30min_R2 1 GNSPPSSGEACREEK 15 1 P41227-2;P41227 P41227-2 NAA10 N-alpha-acetyltransferase 10 1 GNS(0.009)PPS(0.496)S(0.496)GEACREEK 66.60600000000001 0.014875 158150000.0 13145.0 14554.0 17046.0 29256.0 27175.0 22138.0 15472.0 15502.0 17570.0 21159.0 True False 17324.836567014732 19258.295881017966 16819.958902341456 22511.481200694227 23402.220324644553 20753.707360359032 16848.978026764456 13106.522100521679 18498.714330134095 20418.229850298372 0.8484984591728242 0.9431912571371384 0.8237716504154088 1.102518747498832 1.1461434461373043 1.016430293542599 0.8251928864694528 0.6419029561629778 0.9059901110802596 1.0 14.3175701773571 -10.76497659223683 4.99183066582122 1.0000132721320916 0.9194138429474418 0.030502496432259996 0.1396988812747104 2.3168837632783687e-05 3.5177828517421535e-06 0.15187540922348905 0.0368291324790868 1.7180009821088525e-11 10.76497659223683 -0.0805994291846498 GNSPPS(ph)SGEACREEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GNSPPSSGEACREEK 15 1 P41227-2;P41227 P41227-2 NAA10 N-alpha-acetyltransferase 10 1 GNS(0.02)PPS(0.734)S(0.246)GEACREEK 52.966 0.039058999999999996 14304000.0 26683.0 19501.0 28486.0 33330.0 33888.0 40203.0 31204.0 38776.0 33816.0 22769.0 True False 31199.904886727443 21436.930402380836 29165.214273756577 31462.628157317933 27247.889667043473 38094.68390666335 28248.131222603664 37758.17108656806 34310.49502641325 26896.83946069517 1.1599840543466238 0.7970055527790544 1.0843361100614153 1.1697518663222433 1.0130517270202435 1.4163256602074674 1.0502397972774147 1.403814419970969 1.2756329633655206 1.0 14.715149037005446 -6.067194984063255 1.1380473094746764 1.2349501629013702 0.9817298718063904 0.20203609679741963 0.16228911878518099 0.6638745691852718 1.7589341506177905 0.061788211455047926 0.11373111088834027 8.566531495438773e-07 6.067194984063255 -0.2532202910949798 GNSPPSS(ph)GEACR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GNSPPSSGEACR 12 0 P41227-2;P41227 P41227-2 NAA10 N-alpha-acetyltransferase 10 1 GNS(0.175)PPS(0.175)S(0.65)GEACR 86.214 0.009243600000000001 8942200.0 5135.7 7466.8 9721.3 6333.6 7572.3 7221.1 7205.8 5447.8 7062.6 4951.5 True False 6005.072575301355 8208.054557637919 9953.092660235558 5978.748925808248 6088.562173210378 6842.41280397997 6523.214458525747 5304.8010224212285 7165.877163873504 5849.167753947566 1.026654188751651 1.4032858866286329 1.701625441246454 1.0221537793600173 1.0409279455357126 1.1698096364841082 1.1152380531611992 0.9069326176943809 1.2251105568031109 1.0 12.51401565078249 -5.80992383717348 24.999992041326152 1.0697257714657424 1.3798009170045917 0.4003230004499506 0.17306761632453946 108.90382225599456 56153.41511930062 0.048882514089103934 0.07250465370748048 1.5490882608526385e-06 5.80992383717348 0.3100751455388493 GNSRPGT(ph)PSAEGGSTSSTLR ddPTM_PC-9_AZD4547_30min_R2 4 GNSRPGTPSAEGGSTSSTLR 20 1 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 GNS(0.001)RPGT(0.986)PS(0.012)AEGGSTSSTLR;GNS(0.001)RPGT(0.909)PS(0.088)AEGGS(0.001)T(0.001)S(0.001)STLR;GNS(0.003)RPGT(0.985)PS(0.007)AEGGS(0.001)T(0.001)S(0.001)S(0.001)T(0.003)LR;GNS(0.091)RPGT(0.859)PS(0.046)AEGGS(0.001)T(0.001)S(0.001)S(0.001)T(0.001)LR 71.696 0.0026146 126171000.0 30271.1 19305.0 33496.5 42724.3 45900.0 43900.9 33989.9 44033.0 39883.5 44243.4 True False 39896.68012200531 25544.96372014924 33052.314523775705 32874.87271885495 39527.57729167194 41155.769783015036 37014.935252838746 37228.711627678436 41991.66038622098 42694.452032642854 0.9344698953274198 0.5983204492381903 0.7741594738938196 0.7700033881151548 0.9258246776759281 0.9639606043321182 0.866972955280894 0.8719800783299554 0.9835390404850602 1.0 15.381760989324592 -6.243091912312313 4.801401756165727 0.927662226363617 0.7555343297752998 0.4702082892675772 0.08577992581694127 0.168682706877837 10.935837544610946 0.025248900371384796 0.03152308855761237 5.713577040620164e-07 6.243091912312313 -0.17212789658831718 GNSRPGT(ph)PSAEGGSTSSTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GNSRPGTPSAEGGSTSSTLR 20 1 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 GNS(0.049)RPGT(0.931)PS(0.019)AEGGSTSSTLR;GNSRPGT(0.995)PS(0.004)AEGGSTSSTLR;GNS(0.012)RPGT(0.975)PS(0.012)AEGGSTSSTLR 90.1 0.00048983 66303000.0 18387.699999999997 25992.9 28067.5 29235.0 43763.0 53518.0 58452.0 49420.4 54882.0 47363.5 True False 21500.37443637064 28573.303330908377 28736.735646586505 27597.057731148827 35187.95430532411 50711.42186694549 52915.003404167095 48123.16686524212 55684.545423456715 55950.12762074028 0.384277486945367 0.5106923709735467 0.5136134065927317 0.49324387458445784 0.6289164261402007 0.906368296613986 0.9457530421173144 0.8601082591168789 0.9952532333959304 1.0 15.77185380150356 -6.639290573410451 2.1692545439181403 0.9429489901740501 0.478131928016157 0.951829528736983 0.049960737326299715 0.06277812122568889 0.6034577940443371 0.018779829045428815 0.01874148202482296 2.2946128777549673e-07 6.639290573410451 -0.4648170621578931 GNSRPGT(ph)PSAEGGSTSSTLR ddPTM_PC-9_Lapatinib_30min_R1 4 GNSRPGTPSAEGGSTSSTLR 20 1 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 GNS(0.006)RPGT(0.908)PS(0.085)AEGGSTSSTLR;GNS(0.006)RPGT(0.949)PS(0.036)AEGGS(0.001)T(0.001)S(0.003)S(0.001)T(0.003)LR;GNS(0.053)RPGT(0.855)PS(0.086)AEGGS(0.001)T(0.001)S(0.002)S(0.001)T(0.001)LR;GNSRPGT(0.492)PS(0.492)AEGGS(0.004)T(0.004)S(0.004)S(0.002)T(0.002)LR 78.505 0.0027018 91053100.0 23457.2 23904.2 26901.800000000003 25579.9 38621.3 47413.0 40265.600000000006 43749.1 48568.4 46738.7 True False 23122.69602647635 23848.851293569667 24690.037847951044 27461.131178044925 36349.671066397255 45385.25651510123 42350.3557469061 45781.84289994169 43098.11534407448 54817.422019596976 0.4218129049959718 0.4350597020969686 0.4504049431424278 0.5009562683963448 0.6631043512663258 0.8279348944734434 0.7725710948567782 0.8351695722497656 0.78621200626084 1.0 15.742346861543917 -6.418443218302289 1.3955738618707236 0.8420873275239946 0.4268286125033883 0.912052346539192 0.05771763237913746 0.10976807991570157 0.43525873388040875 0.02211451217365052 0.026922647781069578 3.815546772666654e-07 6.418443218302289 -0.4152587150206063 GNSRPGTPS(ph)AEGGSTSSTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GNSRPGTPSAEGGSTSSTLR 20 1 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 GNS(0.058)RPGT(0.326)PS(0.486)AEGGS(0.038)T(0.038)S(0.016)S(0.019)T(0.019)LR 47.208 0.033448 31670000.0 5625.1 5439.0 8517.8 7071.6 11573.0 11493.0 11216.0 9014.8 8771.8 8511.8 True False 6577.318329210757 5978.947974901253 8720.896655936382 6675.401178436534 9305.35372747563 10890.286847729813 10153.539283191987 8778.171051970134 8900.070980384788 10054.921960628271 0.6541391723342406 0.5946289785552611 0.8673261403802547 0.6638938824761826 0.9254526055908041 1.083080195984867 1.0098078655358906 0.8730222955824551 0.8851457042863689 1.0 13.295614264031949 -6.327958200261993 4.922190115777797 0.9679547691305938 0.699979901584317 0.6968542484194642 0.08670921065174728 0.1336708309139091 6.398099121222121 0.028939546122585025 0.033281035254099416 4.6993933689316094e-07 6.327958200261993 -0.26797486754627675 GNT(ph)PATGTTQGK ddPTM_PC-9_AZD4547_30min_R2 1 GNTPATGTTQGK 12 0 Q9P2E9;A0A087WVV2;A2A2S5 Q9P2E9 RRBP1 Ribosome-binding protein 1 1 GNT(0.787)PAT(0.163)GT(0.046)T(0.004)QGK 105.99 0.0042169 6504100.0 21445.0 19144.0 27608.0 30885.0 27957.0 28718.0 22174.0 31477.0 25843.0 25629.0 True False 28264.06391628991 25331.923618675843 27241.899881253255 23764.94041849332 24075.653122947122 26922.258920173048 24147.443043270116 26612.952919502073 27209.008220469856 24731.736510860464 1.1428256929665368 1.0242678918866783 1.101495637772564 0.9609086854074078 0.9734720047811751 1.0885713143656799 0.9763747496123546 1.0760648734800935 1.1001657003955847 1.0 14.594075920031564 -2.5710319856641948 1.486501231551627 1.0317448992949803 88.83363211813857 0.2715928880693079 0.05262290108838078 1492.0513698317604 5.452511272973379 0.014682031384547767 445783.9980051976 0.0026851466780921144 2.5710319856641948 87.80188721884359 GNT(ph)PATGTTQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GNTPATGTTQGK 12 0 Q9P2E9;A0A087WVV2;A2A2S5 Q9P2E9 RRBP1 Ribosome-binding protein 1 1 GNT(0.798)PAT(0.119)GT(0.065)T(0.019)QGK;GNT(0.93)PAT(0.031)GT(0.031)T(0.008)QGK;GNT(0.582)PAT(0.133)GT(0.233)T(0.053)QGK 93.766 0.012565999999999999 13903900.0 56573.0 61164.0 64453.0 59743.0 68949.0 56957.0 56960.0 46192.0 44498.0 35588.4 True False 66149.69153231753 67235.95770120618 65989.80395936362 56395.79339941932 55438.938404537876 53970.074652931944 51564.33644531166 44979.5089444696 45148.69906805471 42040.29520238059 1.5734830408272613 1.5993217311518508 1.56967984267691 1.3414699665626 1.3187095413497136 1.283770116102225 1.2265455367780518 1.069914203217169 1.0739386783729838 1.0 15.359485179332777 -6.423571071549686 0.41640329539694154 0.9874516458557764 1.7178826681304573 0.9527698358223751 0.04551196155120069 0.33030609691088825 0.10813658716988378 0.04726853958425224 0.10317694446397303 3.770760321137569e-07 6.423571071549686 0.7304310222746809 GNT(ph)PATGTTQGK ddPTM_PC-9_Lapatinib_30min_R1 2 GNTPATGTTQGK 12 0 Q9P2E9;A0A087WVV2;A2A2S5 Q9P2E9 RRBP1 Ribosome-binding protein 1 1 GNT(0.668)PAT(0.071)GT(0.221)T(0.041)QGK;GNT(0.902)PAT(0.04)GT(0.052)T(0.005)QGK 122.66 0.00095482 9542900.0 73405.0 75249.0 81380.0 64131.0 53441.0 57912.0 46634.0 43739.0 65015.0 41226.0 True False 72358.23123917163 75074.76556378468 74689.2505358844 68847.40767474443 50297.705449048466 55435.23875946559 49048.48033808559 45771.27361706986 57692.326061698644 48351.85916980795 1.4964932575819925 1.5526758816062889 1.5447027646565068 1.4238833595406895 1.0402434634913802 1.1464965300461636 1.0144073295264855 0.9466290314985558 1.1931769957198068 1.0 15.561283743160454 -6.172018550655405 3.1848842804250044 1.0535681962194152 1.5302103862542935 0.9104004933595726 0.06926396786633429 0.06886747339135872 1.3471021524425826 0.021330869009557826 0.028203236813435797 6.72947911062024e-07 6.172018550655405 0.4766421900348783 GNVDIS(ph)APK ddPTM_PC-9_AZD4547_30min_R2 1 GNVDISAPK 9 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GNVDIS(1)APK 77.37899999999999 0.023144 7866300.0 669020.0 412550.0 726360.0 1293100.0 1164500.0 769090.0 862060.0 891020.0 726130.0 1004000.0 True False 881754.4435195266 545898.7196450436 716727.9918048078 994995.7731958465 1002829.2757331575 720998.6807199629 938781.669968497 753333.3326026871 764511.7493762237 968850.2655938149 0.9101039395175201 0.5634500387017581 0.7397716832595596 1.0269861180107194 1.0350714773438356 0.7441796801057364 0.9689646618335924 0.7775539310411026 0.7890917477404511 1.0 19.885914190874622 -5.621942031161128 8.62570893615902 0.8977039144650695 0.7157929043326849 0.2638329465528264 0.12724879535400968 0.32628602871682083 25.28307643298578 0.034533388252170685 0.05992143126109501 2.3881300248996194e-06 5.621942031161128 -0.18191101013238453 GNVFS(ph)SPTAAGT(ph)PNKETAGLK ddPTM_PC-9_AZD4547_30min_R2 1 GNVFSSPTAAGTPNKETAGLK 21 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;E9PGZ1;Q05682-4 E7EX44;Q05682-5 CALD1 Caldesmon 2 GNVFS(0.917)S(0.088)PT(0.295)AAGT(0.696)PNKET(0.005)AGLK 70.112 0.010357 10366000.0 34384.0 34455.0 36232.0 47384.0 42799.0 42716.0 36273.0 39942.0 39080.0 37086.0 True False 45317.39676837087 45591.90494575197 35751.54000643175 36460.35087550227 36857.09761451563 40044.96176732753 39501.22672988798 33769.88167585066 41145.68901659876 35787.63042809989 1.2662865975275177 1.273957074004931 0.998991539220775 1.018797568862625 1.0298837104782443 1.1189609730596985 1.103767593924638 0.9436188222547162 1.1497181714576947 1.0 15.127173402688992 -5.25450140376056 24.873962375591034 1.0466515635009743 1.2701218713003095 0.6960132611891634 0.05938319517472195 263.88716096460746 946079.0358125996 0.01487616429882068 0.037622142846091874 5.5654283535410964e-06 5.25450140376056 0.2234703077993352 GNVFS(ph)SPTAAGT(ph)PNKETAGLK ddPTM_PC-9_Lapatinib_30min_R1 1 GNVFSSPTAAGTPNKETAGLK 21 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;E9PGZ1;Q05682-4 E7EX44;Q05682-5 CALD1 Caldesmon 2 GNVFS(0.558)S(0.432)PT(0.196)AAGT(0.771)PNKET(0.042)AGLK 65.155 0.016057 5721700.0 57370.0 42582.0 55397.0 38465.0 41465.0 40805.0 25962.0 31156.0 36753.0 25565.0 True False 56551.8932796305 42483.40399523028 50842.472498603944 41293.844415478445 39026.11022332656 39059.86527110087 27306.185326958377 32603.621500569923 32613.49011375238 29983.87618677875 1.8860768009896864 1.4168749807592633 1.6956604336907812 1.3772016719334899 1.301569883100536 1.302695656418303 0.9106956404455442 1.0873718026806132 1.0877009333480754 1.0 14.871899280312299 -6.122119445765186 0.5733778111073697 0.9934215621057569 1.8021491767665558 0.8068798438394708 0.12820238850968213 0.48509971811829955 0.3097652080723707 0.08930098892464713 0.21715475582707855 7.548845801571161e-07 6.122119445765186 0.8087276146607989 GNVFSS(ph)PTAAGT(ph)PNKETAGLK ddPTM_PC-9_Lapatinib_30min_R1 1 GNVFSSPTAAGTPNKETAGLK 21 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;E9PGZ1;Q05682-4 E7EX44;Q05682-5 CALD1 Caldesmon 2 GNVFS(0.47)S(0.526)PT(0.009)AAGT(0.994)PNKET(0.001)AGLK 81.34100000000001 0.0028033000000000003 5921300.0 57691.0 53001.0 54559.0 44616.0 38110.0 41074.0 38593.0 33562.0 38305.0 31899.0 True False 56868.31576076629 52878.27944087172 50073.36962383038 47897.209474612944 35868.444727142814 39317.360768170496 40591.15670300075 35121.41304410476 33990.68753046781 37412.699647254274 1.520027057575351 1.4133778085899895 1.3384056776428128 1.2802393285224507 0.9587237773624606 1.0509094809750252 1.084956634664554 0.938756448351685 0.9085334084668866 1.0 15.191240452018837 -5.901706800453564 1.0485888374841885 0.9771543397774682 1.4992237840630538 0.9100419105767124 0.06254167765726362 0.1631201131936504 0.35735871597706964 0.026024722868227004 0.06190645769091421 1.2539874773772373e-06 5.901706800453564 0.5220694442855855 GNVFSS(ph)PTAAGTPNK ddPTM_PC-9_AZD4547_30min_R2 1 GNVFSSPTAAGTPNK 15 0 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;E9PGZ1;Q05682-4 E7EX44;Q05682-5 CALD1 Caldesmon 1 GNVFS(0.083)S(0.862)PT(0.054)AAGT(0.001)PNK 107.61 0.0040204 0.0 23443.0 28428.0 25768.0 23855.0 20034.0 23132.0 17651.0 22854.0 23272.0 16277.0 True False 30897.386355308226 37616.795060160686 25426.29948348789 18355.59830607604 17252.624912012117 21685.552383224574 19221.90480548212 19322.439432674644 24502.11040927038 15707.14718433321 1.9670909040774909 2.394883973436044 1.6187725998295133 1.168614395132458 1.0983932797943357 1.3806168700611916 1.2237680452026731 1.2301686108822765 1.5599338391448663 1.0 13.939133554022806 -5.4808825603912945 3.723275369956148 1.2501195353108923 2.1726906683429115 0.8205202236267303 0.17510461022439322 0.0834490274321273 2.3833117751858457 0.04596503024053771 0.09800593987087322 3.3045888989468772e-06 5.4808825603912945 0.9225711330320192 GNVFSS(ph)PTAAGTPNK ddPTM_PC-9_Lapatinib_30min_R1 2 GNVFSSPTAAGTPNK 15 0 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;E9PGZ1;Q05682-4 E7EX44;Q05682-5 CALD1 Caldesmon 1 GNVFS(0.037)S(0.805)PT(0.153)AAGT(0.005)PNK;GNVFS(0.061)S(0.863)PT(0.076)AAGTPNK 134.25 1.0505999999999999e-05 6737100.0 20018.7 49305.0 41712.0 32352.0 49079.0 40199.0 48735.0 43893.0 37447.0 41015.0 True False 19733.229667020045 49190.83730179017 38282.6003729763 34731.274003108265 46192.26971302654 38479.782478445886 51258.25983781361 45932.42901927449 33229.32452560838 48104.38810094781 0.41021683147927285 1.0225852410504097 0.7958234557030363 0.7219980416386161 0.9602506452444908 0.7999225018244794 1.0655630777434972 0.9548490446003506 0.6907753291836106 1.0 15.553880882748997 -4.751117612086572 24.998505468652606 0.8854283974434763 0.4102158501014392 0.5723898968295278 0.12439631430226307 320.9245664058146 777201.9103228959 0.030475339946973035 0.41667591327103704 1.773709074429946e-05 4.751117612086572 -0.47521254734203716 GNVFSSPT(ph)AAGTPNKETAGLK ddPTM_PC-9_AZD4547_30min_R2 1 GNVFSSPTAAGTPNKETAGLK 21 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;E9PGZ1;Q05682-4 E7EX44;Q05682-5 CALD1 Caldesmon 1 GNVFS(0.005)S(0.017)PT(0.878)AAGT(0.099)PNKETAGLK 101.61 0.00011853 13603000.0 58773.0 48280.0 70344.0 76708.0 76790.0 72165.0 71769.0 56738.0 60032.0 80460.0 True False 77461.5914456567 63885.56583314193 69411.19259804687 59024.155726786 66129.03399188418 67652.51114194197 78156.30196502454 47970.445809534234 63205.168962242955 77643.11989011796 0.9976620150669091 0.8228103909728771 0.8939773761832204 0.7601981451842497 0.8517050072881056 0.8713265417165759 1.0066094983770983 0.6178325378658526 0.8140472594570147 1.0 16.244570469774757 -4.757284382010836 24.62631001724513 0.8411615369535409 0.9976622950903463 0.14583890807446587 0.10673151255918695 193.62712496258413 1147423.952943568 0.026017333039598176 0.19453875548206837 1.7487012399707523e-05 4.757284382010836 0.15650075813680542 GNVFSSPTAAGT(ph)PNKETAGLK ddPTM_PC-9_AZD4547_30min_R2 1 GNVFSSPTAAGTPNKETAGLK 21 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;E9PGZ1;Q05682-4 E7EX44;Q05682-5 CALD1 Caldesmon 1 GNVFSSPT(0.036)AAGT(0.927)PNKET(0.036)AGLK 84.499 0.00033607 10562000.0 22878.0 16237.0 24217.0 35727.0 29548.0 29492.0 25200.0 28146.0 23722.0 34006.0 True False 30152.72810803827 21485.29271815919 23895.866756893294 27490.69212664759 25445.770235606153 27647.860577816817 27442.75118113135 23796.682430736888 24975.89649057715 32815.460290620846 0.9188573873716583 0.6547308045622634 0.7281892908179958 0.8377359903894094 0.7754201833603089 0.8425254539464434 0.8362750648045885 0.7251668030857498 0.7611015134142622 1.0 15.002088048955235 -11.493254843307863 2.5583025143225027 1.181768974759317 0.7835309132839128 0.4441936764397506 0.07151303496184587 31130314.975796647 14664645.155628568 33517843.468751177 0.017887182721067447 3.2117753209479855e-12 11.493254843307863 -0.3982380614754042 GNVFSSPTAAGT(ph)PNKETAGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GNVFSSPTAAGTPNKETAGLK 21 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;E9PGZ1;Q05682-4 E7EX44;Q05682-5 CALD1 Caldesmon 1 GNVFSSPT(0.002)AAGT(0.711)PNKET(0.287)AGLK 105.24 6.1885e-05 11227000.0 14254.0 16087.0 13504.0 18393.0 26141.0 21366.0 22964.0 21075.0 20489.0 16714.0 True False 16666.9206706672 17684.011044720795 13825.986574205193 17362.499840910572 21018.85870473864 20245.529347306656 20788.68367503752 20521.803580808275 20788.61286362023 19744.115892048787 0.8441462135754171 0.8956598077831571 0.7002585808247357 0.8793759080345895 1.0645631751585902 1.0253955891466275 1.052905270040954 1.0393883267810777 1.0529016835842255 1.0 14.26913514736221 -6.146329462635461 4.232593168781305 1.0408968379669943 0.817555352847085 0.8171130395405468 0.04907698022365423 0.09251083868512258 2.7793627946805377 0.01464176892948461 0.019278245712031003 7.139545034505863e-07 6.146329462635461 -0.22334148511990926 GNVFSSPTAAGT(ph)PNKETAGLK ddPTM_PC-9_Lapatinib_30min_R1 1 GNVFSSPTAAGTPNKETAGLK 21 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;E9PGZ1;Q05682-4 E7EX44;Q05682-5 CALD1 Caldesmon 1 GNVFS(0.001)S(0.001)PT(0.011)AAGT(0.979)PNKET(0.007)AGLK 87.958 0.00031724 8556200.0 70384.0 61369.0 47581.0 55761.0 57880.0 62940.0 43805.0 49963.0 46332.0 48891.0 True False 69380.31125315512 61226.903851000156 43669.07384797145 59861.84995324306 54475.61219645826 60248.202920306074 46073.00856048886 52284.463378898916 41113.60226241051 57341.74420683749 1.2099442075374145 1.067754472730172 0.7615581711371155 1.0439488854283068 0.9500166580207119 1.0506866115370452 0.8034811148105095 0.911804551851502 0.7169925301558595 1.0 15.80729816833234 -7.2614481266127955 24.999999592212415 0.850719925695653 1.0034093290564354 0.26648720047901897 0.12575719169516772 1.1729172423841947 3341223.356475209 0.05055179613466716 0.03658653278333277 5.4771151730053025e-08 7.2614481266127955 0.1526894033607824 GNVFSSPTAAGTPNKET(ph)AGLK ddPTM_PC-9_Lapatinib_30min_R1 1 GNVFSSPTAAGTPNKETAGLK 21 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;E9PGZ1;Q05682-4 E7EX44;Q05682-5 CALD1 Caldesmon 1 GNVFS(0.001)S(0.001)PT(0.001)AAGT(0.064)PNKET(0.934)AGLK 87.228 0.00032122 8253600.0 49561.0 31053.0 27805.0 35094.0 36318.0 27112.0 31635.0 26319.0 24495.0 31575.0 True False 48854.25105162571 30981.09868639064 25518.980230403857 37674.92983015213 34181.84664393525 25952.482961158854 33272.9055087562 27541.876822233266 21736.115156214837 37032.69667895712 1.319219377274944 0.8365877039679601 0.6890932208267825 1.0173423274238609 0.9230180275626053 0.7007991663730415 0.8984737405759239 0.7437178302460277 0.5869438929778459 1.0 15.17651198830027 -4.762582210694083 6.195539330130304 0.8164128006584069 1.3356150701885592 0.5535782074092596 0.13405435759565393 0.09528000688978998 15.27411987924852 0.033269373922213706 0.20991676494419198 1.7274989389831593e-05 4.762582210694083 0.5192022695301522 GNVVPS(ph)PLPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GNVVPSPLPTR 11 0 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 1 GNVVPS(0.931)PLPT(0.069)R;GNVVPS(0.932)PLPT(0.068)R;GNVVPS(0.999)PLPT(0.001)R 78.814 0.017973 804352000.0 237249.0 375214.0 357102.0 258984.0 348255.0 220897.0 287430.0 230206.0 204142.0 186234.0 True False 277410.56981865584 412462.76621706085 365616.66599687666 244473.9661174563 280016.9327194351 209312.77245305607 260202.5495870069 224163.33642341875 207127.19055127958 219996.74997246705 1.2609757637482109 1.8748584525393273 1.6619184876259954 1.111261717039241 1.2728230428607679 0.9514357483883371 1.182756334443903 1.0189393091101262 0.9415011384359173 1.0 17.74712268530839 -5.777965603310787 7.4436920527897446 1.0764242972274847 1.6277151051020975 0.6696335188099386 0.17048076713551907 0.08260690966352746 22.19806660186478 0.04658992441513869 0.07224724193218485 1.6673792659334347e-06 5.777965603310787 0.5512908078746128 GNVVPS(ph)PLPTR ddPTM_PC-9_Lapatinib_30min_R1 1 GNVVPSPLPTR 11 0 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 1 GNVVPS(1)PLPTR 82.85 0.022456 407390000.0 32612.0 69779.0 66660.0 60609.0 74128.0 67668.0 75237.0 80753.0 70613.0 55039.0 True False 32146.94689969164 69617.43101270904 61179.47211504128 65066.388045696964 69767.93678125527 64773.99738181232 79132.40372253176 84505.07918332024 62659.820352145354 64552.41781514241 0.4979975651996532 1.0784635706763335 0.947748731739837 1.0079620601048034 1.0807950986599517 1.0034325525544905 1.2258627391640355 1.309092394111649 0.9706812304317267 1.0 15.978183512333505 -4.761319515521547 24.9947576985979 1.076469060841307 0.49799692856907113 0.7095200136053419 0.10958550434243197 1.6281251003742558 338129.63210713805 0.029114150297789448 0.16309387296290528 1.732528887021988e-05 4.761319515521547 -0.5784721322722359 GNVVPS(ph)PLPTRR ddPTM_PC-9_AZD4547_30min_R2 3 GNVVPSPLPTRR 12 1 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 1 GNVVPS(0.655)PLPT(0.345)RR;GNVVPS(0.98)PLPT(0.02)RR;GNVVPS(0.996)PLPT(0.004)RR 92.773 0.0026035 942310000.0 484446.0 547266.0 721580.0 843770.0 897780.0 870320.0 677350.0 866330.0 733105.0 781737.0 True False 638489.7508972244 724159.032130079 712011.3777280044 649251.8626165492 773138.7438108347 815898.7528172238 737632.8377991781 732458.6047829287 771855.4336364787 754368.6255722245 0.8463895889266333 0.9599538045219868 0.9438507297250198 0.8606559719050627 1.0248818914285733 1.081565066678543 0.9778148411721769 0.9709558164979675 1.0231807202360645 1.0 19.52491014955823 -6.274746107330998 24.749319928738633 1.0132765423186931 0.9097396298022424 0.6142769232865508 0.04269474097119908 507.07249579105286 943107.3036839258 0.013698731741366111 0.015621216432143897 5.311948950445459e-07 6.274746107330998 -0.1035369125164507 GNVVPS(ph)PLPTRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 GNVVPSPLPTRR 12 1 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 1 GNVVPS(0.886)PLPT(0.114)RR;GNVVPS(0.84)PLPT(0.16)RR;GNVVPS(0.565)PLPT(0.435)RR;GNVVPS(0.988)PLPT(0.012)RR;GNVVPS(0.996)PLPT(0.004)RR;GNVVPS(0.583)PLPT(0.417)RR;GNVVPS(0.938)PLPT(0.062)RR;GNVVPS(0.905)PLPT(0.095)RR 127.3 0.00035003 702401300.0 1586840.0 1541484.0 1909398.0 2060505.0 2343554.0 1968660.0 2123188.0 1632563.0 1851789.0 1716247.0 True False 1855460.6704813773 1694512.3442071471 1954925.2897522352 1945061.585097342 1884351.4170431504 1865420.0039721383 1922064.262090032 1589709.9510934837 1878867.9108843983 2027388.9952962217 0.9151971697519626 0.835810171673326 0.964257621151091 0.9593923956429236 0.929447393378905 0.9201095637295702 0.9480490752142015 0.7841168886591551 0.9267426799906631 1.0 20.951191494706414 -5.354348379929034 0.004713133814582524 1.8131253901741866 8.591036930616781e-08 0.05853782887033532 0.058522797031959804 123055.79972404637 110.07840804850963 20583.164919429157 21772.686195089573 4.422334816478894e-06 5.354348379929034 -1.8131253042638174 GNVVPS(ph)PLPTRR ddPTM_PC-9_Lapatinib_30min_R1 4 GNVVPSPLPTRR 12 1 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 1 GNVVPS(0.991)PLPT(0.009)RR;GNVVPS(0.914)PLPT(0.086)RR;GNVVPS(0.999)PLPT(0.001)RR;GNVVPS(0.928)PLPT(0.072)RR 127.3 0.00035003 915960000.0 1482470.0 1602170.0 1593130.0 1430940.0 1617490.0 1621630.0 1424030.0 1454000.0 1638390.0 1137880.0 True False 1461329.7059483 1598460.273802032 1462149.0010596379 1536176.1010759056 1522352.418307692 1552276.6651041612 1497759.305567698 1521558.148087964 1453857.26518844 1334561.0418702064 1.094989033922678 1.197742346473719 1.0956029399828981 1.151072189941318 1.1407139655255645 1.1631365043661517 1.1222860990073495 1.1401188108681086 1.0893898589689506 1.0 20.347933864155415 -8.662858333756633 1.7318297129217826 0.9999790789411058 1.1404728521414813 0.6818425188317092 0.028907157383504783 0.29592957818874327 1.8095173290201947 0.025251689943188757 0.007177648182851689 2.1734100265096586e-09 8.662858333756633 0.14049377320037548 GNVVPSPLPT(ph)R ddPTM_PC-9_AZD4547_30min_R2 3 GNVVPSPLPTR 11 0 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 1 GNVVPS(0.043)PLPT(0.957)R;GNVVPS(0.31)PLPT(0.69)R;GNVVPS(0.15)PLPT(0.85)R 89.43 0.022706999999999998 1238570000.0 357863.0 564174.0 522983.0 441153.0 466777.0 591460.0 591520.0 693160.0 565413.0 425792.0 True False 471655.98998718755 746532.2124761192 516047.9037089783 339451.9915959068 401973.07070751145 554475.9127002417 644164.1340739212 586048.0492322027 595299.5768664825 410885.151680998 1.1479022497103295 1.816887783415717 1.2559419623652557 0.826148110261842 0.9783100437262682 1.349466901959807 1.5677474141826275 1.4263062240983515 1.4488223155083972 1.0 18.6483756706439 -6.984628459360552 24.880947066278683 1.4051535107011583 1.2151162478186244 0.061706019822338476 0.2772412989408277 620.7131767434827 1004705.5365865336 0.1053132662488291 0.0928477306062329 1.036028113790743e-07 6.984628459360552 -0.19003726288253397 GNVVPSPLPT(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GNVVPSPLPTR 11 0 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 1 GNVVPS(0.001)PLPT(0.999)R 110.15 0.0048223 42097000.0 38280.0 63046.0 61705.0 49526.0 64097.0 33402.0 58334.0 33393.0 32544.0 32858.0 True False 44760.04793553675 69304.79022350143 63176.28121751568 46751.218785458404 51537.65297416444 31650.340319139596 52808.18121841307 32516.46913280811 33019.894432800844 38814.89529621512 1.1531667828536265 1.785520473380213 1.6276298244626737 1.2044659254824053 1.3277802910675358 0.815417382363153 1.3605132981915435 0.8377317234700572 0.8507016231992939 1.0 15.244322775419572 -6.30935466355217 1.3217800396969934 0.979957203650763 1.5368470743950087 0.4948715115607101 0.22598574509723565 0.35381040403096337 1.2562824225454023 0.0888715734066729 0.12058996281570145 4.905071433179509e-07 6.30935466355217 0.5568898707442457 GNVVPSPLPT(ph)R ddPTM_PC-9_Lapatinib_30min_R1 3 GNVVPSPLPTR 11 0 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 1 GNVVPS(0.114)PLPT(0.886)R;GNVVPS(0.004)PLPT(0.996)R;GNVVPS(0.01)PLPT(0.99)R 108.23 0.0054053999999999994 1325020000.0 121657.0 305393.0 326228.0 260284.0 345002.0 323028.0 385803.0 382833.0 273590.0 275221.0 True False 119922.14887083884 304685.8812717895 299406.7931164965 279426.1536419703 324709.6606600296 309212.84545504686 405777.99159142305 400620.8187805783 242775.4131695782 322792.58314106957 0.37151457355025236 0.943906078345775 0.9275516500502963 0.8656523360075257 1.0059390383146511 0.9579304531910884 1.2570858587977112 1.241109119925149 0.7521096389735771 1.0 18.30024790438916 -4.627556431956116 2.213410351541764 1.013942265366867 4.379558264490591e-18 0.6198964971329595 0.14629457447098865 0.8086331752706228 3.1121885329895256 0.0404580413634577 1.888680544502622 2.357455849704802e-05 4.627556431956116 -1.013942265366867 GNVVPSPLPT(ph)RR ddPTM_PC-9_AZD4547_30min_R2 2 GNVVPSPLPTRR 12 1 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 1 GNVVPS(0.107)PLPT(0.893)RR;GNVVPS(0.232)PLPT(0.768)RR 122.1 0.0014202 153769000.0 363081.0 417061.0 632955.0 703256.0 615382.0 593677.0 572840.0 781619.0 562427.0 587572.0 True False 478533.2054460455 551867.8121776307 624561.6031345492 541131.19439689 529946.8315665282 556554.2833397714 623821.6502618754 660837.7433678003 592155.7430025231 567001.2831229967 0.8439719974006474 0.9733096354526536 1.1015170895108297 0.9543738444759483 0.9346483814774181 0.9815749979864525 1.1002120609426433 1.1654960280300601 1.0443640263757037 1.0 19.11299247442458 -7.2307748862292165 5.951960716684611 1.09149136686988 0.9690878218842539 0.3679630594688045 0.07131401848163099 0.20081859586848244 23.07566057965905 0.028776733203174688 0.021624287077028063 5.8779395282025585e-08 7.2307748862292165 -0.12240354498562611 GNVVPSPLPT(ph)RR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GNVVPSPLPTRR 12 1 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 1 GNVVPS(0.143)PLPT(0.857)RR;GNVVPS(0.001)PLPT(0.999)RR 100.55 0.0025441999999999995 261340000.0 110433.0 130943.0 155936.0 167279.0 187445.0 147824.0 191144.0 147557.0 126910.0 154945.0 True False 129127.12574882763 143942.15566786093 159654.10563057326 157906.89995583554 150716.497835191 140071.8492107206 173037.4565572795 143683.78509956502 128765.81865986846 183035.3019560551 0.7054766177282551 0.7864174513308911 0.8722585420647684 0.8627128115086092 0.8234285748405872 0.7652723147600806 0.945377502088772 0.7850058626071053 0.7035026428441864 1.0 17.48176240188163 -11.986885581635024 2.347958832537998 3.317367378090712 0.8114361790518951 0.3992973983319913 0.07123582722782298 3711801.060961537 778432.5147996749 45160455.40624478 0.018574512353075664 1.030657619693107e-12 11.986885581635024 -2.505931199038817 GNYDEGFGHRPHK ddPTM_PC-9_AZD4547_30min_R2 1 GNYDEGFGHRPHK 13 1 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 0 47.038999999999994 0.0351 2503800.0 16460.0 15593.0 24904.0 32750.0 24477.0 21642.0 20520.0 24614.0 20194.0 22249.0 False True 21693.93761073127 20633.132312265567 24573.756688015455 25199.993482456095 21078.791053774614 20288.722318768203 22346.24024749268 20810.471873451203 21261.4136131319 21470.069282068547 1.010426996099621 0.9610184318081368 1.1445587978860905 1.1737266960522907 0.9817756420273538 0.9449770306848992 1.0408089491427908 0.9692782822471733 0.9902815558629373 1.0 14.390039226206566 GNYDEGFGHRPHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GNYDEGFGHRPHK 13 1 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 0 56.551 0.020534 2539500.0 13923.0 18504.0 19460.0 22259.0 20836.0 19394.0 24000.0 18808.0 15406.0 13826.0 False True 16279.888908215193 20340.95483132429 19924.000202460975 21011.900394651682 16753.335372477504 18376.944498814246 21726.546255047044 18314.30992872325 15631.283604711458 16332.544353444217 0.9967760414979115 1.245424741616255 1.2198956740172202 1.286505025790466 1.0257639599763004 1.1251734023265583 1.3302609676039445 1.121338447482074 0.9570635944065337 1.0 13.995461937145977 -8.140568626209209 4.47695157362959 0.980997077805778 1.1793590630189907 0.36991806119471515 0.10087989186103026 0.2377545919773249 7.359750624735027 0.07460382750583165 0.0261667698697877 7.234880693363835e-09 8.140568626209209 0.1983619852132127 GNYPGPS(ph)SPVVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GNYPGPSSPVVVR 13 0 H3BV44;H3BRD5;B2RTY4-5;B2RTY4-2;B2RTY4;B2RTY4-4;H3BP49;H3BU05 H3BV44 MYO9A Unconventional myosin-IXa 1 GNYPGPS(0.786)S(0.214)PVVVR 124.81 0.00014916 5164400.0 13411.0 15897.0 17907.0 20137.0 21876.0 23183.0 21694.0 19671.0 21521.0 18880.0 True False 15681.217420676152 17475.149100387058 18333.970792675675 19008.78917503486 17589.554838179967 21967.242668660958 19638.98726904128 19154.65709314732 21835.703911268054 22302.794546002242 0.703105495965168 0.7835407829428023 0.8220481408668145 0.8523052631734964 0.7886704422577789 0.9849547160267667 0.8805617264030957 0.858845605811348 0.9790568561365368 1.0 14.444936871088002 -2.113569762476558 0.1742039312652862 1.009916918408706 1.0085981201035844e-11 0.72638019685951 0.048672332916393446 26.331929815588865 0.3474482888589504 0.12263395690456776 6.6926361867206206 0.007698927634395962 2.113569762476558 -1.00991691839862 GNYPGPSS(ph)PVVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GNYPGPSSPVVVR 13 0 H3BV44;H3BRD5;B2RTY4-5;B2RTY4-2;B2RTY4;B2RTY4-4;H3BP49;H3BU05 H3BV44 MYO9A Unconventional myosin-IXa 1 GNYPGPS(0.245)S(0.755)PVVVR 69.92 0.029401999999999998 4992600.0 11282.0 12677.0 17157.0 14201.0 18923.0 13652.0 22377.0 13289.0 18518.0 18469.0 True False 13191.819770342878 13935.488780625694 17566.08794828483 13405.364010263185 15215.173989892102 12936.065087027526 20257.28856454949 12940.177830859373 18788.790717385873 21817.283499476453 0.604649968024637 0.638736201093051 0.8051455145048815 0.6144378153487748 0.6973908548356728 0.5929273957199095 0.9284972881722696 0.5931159042403192 0.8611883655376594 1.0 14.413183860413126 -9.989340805276598 0.2600145476943592 1.1471606235724656 0.635104691751937 0.4782978599186012 0.10492209420305874 8.696269613674005 0.714625507726765 1.2072920295834946 0.16485854030968497 1.0248473789037958e-10 9.989340805276598 -0.5120559318205287 GPAADPS(ph)SPGTSGVGPAAGAGDSR ddPTM_PC-9_AZD4547_30min_R2 1 GPAADPSSPGTSGVGPAAGAGDSR 24 0 A0A0U1RRM4 A0A0U1RRM4 1 GPAADPS(0.566)S(0.41)PGT(0.019)S(0.006)GVGPAAGAGDSR 193.06 2.8166e-23 27562000.0 17367.0 18774.0 28089.0 34546.0 23876.0 23313.0 19037.0 31537.0 19740.0 24014.0 True False 22889.344743959304 24842.328354420184 27716.521506973448 26581.953430379486 20561.22952975946 21855.234424611546 20731.256120444334 26663.681298164898 20783.416099991267 23173.277169292716 0.9877474203040364 1.072024822943004 1.196055322882905 1.1470951318704141 0.8872819057722866 0.9431222983675468 0.8946190894361569 1.1506219471407944 0.8968699570698488 1.0 14.500174464389076 -6.252198191431739 24.98098718045237 0.965295445474105 1.1054891633286894 0.3747371605229257 0.08759083830664949 753.8577559173503 2037845.318642244 0.026751771251412662 0.03405842085706356 5.595022129160475e-07 6.252198191431739 0.14019371785458445 GPAADPS(ph)SPGTSGVGPAAGAGDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPAADPSSPGTSGVGPAAGAGDSR 24 0 A0A0U1RRM4 A0A0U1RRM4 1 GPAADPS(0.582)S(0.402)PGT(0.013)S(0.004)GVGPAAGAGDSR 162.92 1.7343e-08 10007000.0 51483.0 44095.0 52372.0 53556.0 63329.0 57620.0 62755.0 42653.0 47460.0 39850.0 True False 60198.05506440011 48472.460186297234 53620.747101916044 50555.430950894675 50920.13706103036 54598.305765787205 56810.392093144874 41533.40394458912 48154.01271450127 47074.4895475736 1.2787829595807685 1.0296969898592494 1.139061678995516 1.0739453881874435 1.0816928138874524 1.1598278874720462 1.2068190784253146 0.8822911165635764 1.022932233090636 1.0 15.522657830603995 -7.760209600979111 24.999936773533438 0.9644587543445334 1.13052712175152 0.5188177482114285 0.0747786955406626 25.887986596725145 526310.4412807721 0.03616241996854918 0.019378225031873607 1.736962326562792e-08 7.760209600979111 0.1660683674069866 GPAADPS(ph)SPGTSGVGPAAGAGDSR ddPTM_PC-9_Lapatinib_30min_R1 2 GPAADPSSPGTSGVGPAAGAGDSR 24 0 A0A0U1RRM4 A0A0U1RRM4 1 GPAADPS(0.498)S(0.498)PGT(0.002)S(0.001)GVGPAAGAGDSR;GPAADPS(0.499)S(0.499)PGT(0.001)SGVGPAAGAGDSR 279.97 8.079199999999999e-111 39608000.0 58901.0 49426.0 54295.0 45298.0 49622.0 48574.0 46754.0 43747.0 56650.0 39474.0 True False 58061.06093887953 49311.557133724404 49831.07468476091 48629.366029698285 46703.33152060559 46496.60325152444 49174.69335092106 45779.645326275284 50269.48044905371 46297.02830420121 1.2540990872541768 1.0651127931951876 1.076334194871834 1.0503776983302713 1.0087760107135757 1.0043107507033042 1.0621565822283827 0.9888247043735424 1.0858036096561305 1.0 15.498631972853898 GPAADPSS(ph)PGTSGVGPAAGAGDSR ddPTM_PC-9_AZD4547_30min_R2 3 GPAADPSSPGTSGVGPAAGAGDSR 24 0 A0A0U1RRM4 A0A0U1RRM4 1 GPAADPS(0.305)S(0.675)PGT(0.014)S(0.006)GVGPAAGAGDSR;GPAADPS(0.003)S(0.997)PGTSGVGPAAGAGDSR;GPAADPS(0.137)S(0.624)PGT(0.196)S(0.043)GVGPAAGAGDSR 324.71 5.542299999999998e-200 46508000.0 76321.0 64630.0 98300.0 134761.0 122449.0 110352.0 94455.0 118973.0 81816.0 99021.0 True False 100589.49042458188 85520.38359146574 96996.47777192104 103693.93348669517 105449.06997359349 103451.67199522712 102861.31201641918 100588.45657756203 86140.62672932551 95554.30492964672 1.0526944913538159 0.8949924721280887 1.0150927040214057 1.085183274192004 1.1035512220117338 1.082647946331617 1.0764696796460647 1.0526836718829338 0.9014834736409608 1.0 16.54403325077152 -4.452157818757186 22.901307079984136 1.0294008544801172 2.022885103260432 0.009116723016588613 0.07049849290252189 2493.086577595801 1666150.1422925312 0.018116020420655 135682.11470888296 3.530548494817789e-05 4.452157818757186 0.9934842487803146 GPAADPSS(ph)PGTSGVGPAAGAGDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GPAADPSSPGTSGVGPAAGAGDSR 24 0 A0A0U1RRM4 A0A0U1RRM4 1 GPAADPS(0.24)S(0.518)PGT(0.24)S(0.002)GVGPAAGAGDSR;GPAADPS(0.006)S(0.667)PGT(0.309)S(0.019)GVGPAAGAGDSR;GPAADPS(0.328)S(0.667)PGT(0.004)S(0.001)GVGPAAGAGDSR 276.88 1.8525999999999996e-110 45258000.0 85465.0 85852.0 104752.0 115845.0 118724.0 108989.0 108431.0 97191.0 94640.0 84363.0 True False 99932.53648930624 94374.81918389798 107249.68495417244 109354.58022455758 95460.8844673653 103273.42497583084 98159.63070754192 94639.83923237662 96023.93095871042 99657.34408285927 1.002761386117396 0.9469931197988863 1.0761844592707646 1.0973057854485426 0.9578911152598562 1.0362851421162198 0.9849713697560303 0.9496524325762595 0.9635409396308225 1.0 16.604688505552176 -7.452728054483187 4.830410167549431 0.9672255679240447 1.019369799140163 0.19605766768687083 0.04505084026418092 0.3612582803947746 15.991455105691504 0.020914866043163644 0.013514897149767686 3.525915869181061e-08 7.452728054483187 0.05214423121611822 GPAADPSS(ph)PGTSGVGPAAGAGDSR ddPTM_PC-9_Lapatinib_30min_R1 2 GPAADPSSPGTSGVGPAAGAGDSR 24 0 A0A0U1RRM4 A0A0U1RRM4 1 GPAADPS(0.066)S(0.831)PGT(0.036)S(0.067)GVGPAAGAGDSR;GPAADPS(0.023)S(0.924)PGT(0.027)S(0.027)GVGPAAGAGDSR 152.09 9.4442e-07 35470000.0 64973.0 52528.0 55949.0 49725.0 57254.0 52704.0 43072.0 44875.0 54019.0 45241.0 True False 64046.47310541103 52406.37464331072 51349.08918938559 53381.94237773735 53886.43228569491 50449.97277902466 45302.0574070854 46960.05632424173 47934.81137471197 53060.84657015673 1.2070382823751062 0.9876656335292225 0.9677397272863358 1.0060514640895537 1.015559226226189 0.9507947204031133 0.8537756243143857 0.8850227495362597 0.9033932640206344 1.0 15.695360073073536 -1.5228787452803376 0.6841707713229341 0.9286151628748036 29.507511680071698 0.6842533199225891 0.05202501743540708 167.5682805650721 0.9473468126572221 0.022996802551985874 7304.848137077274 0.029999999999999995 1.5228787452803376 28.578896517196895 GPAFNMAS(ph)PESDFGINLK ddPTM_PC-9_AZD4547_30min_R2 3 GPAFNMASPESDFGINLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GPAFNMAS(0.609)PES(0.391)DFGINLK;GPAFNMAS(0.864)PES(0.136)DFGINLK;GPAFNMAS(0.907)PES(0.093)DFGINLK 171.72 5.1153e-08 30522000.0 74247.0 81882.0 101941.0 128573.0 114332.0 108738.0 78443.0 140119.0 99100.0 108121.0 True False 97856.00156646213 108348.75521021795 100589.19573293379 98932.48128304807 98458.97531397472 101938.59567037306 85424.27503577339 118466.82816430106 104338.2236833401 104335.71669947109 0.9378955228565387 1.0384627492645306 0.9640916736372379 0.9482129841309614 0.9436746919329289 0.9770249239193641 0.8187443163095312 1.1354388689880117 1.0000240280504924 1.0 16.670873587083463 -7.78025859183141 24.999993982417816 1.0507985103007533 0.9521456313236989 0.3411100046460446 0.062145893862339305 283.01634026211775 375961.7913915553 0.03291608288810943 0.015854154255741455 1.6585990342431923e-08 7.78025859183141 -0.09865287897705444 GPAFNMAS(ph)PESDFGINLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GPAFNMASPESDFGINLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GPAFNMAS(0.536)PES(0.464)DFGINLK;GPAFNMAS(0.99)PES(0.01)DFGINLK;GPAFNMAS(0.911)PES(0.089)DFGINLK 93.495 0.0010302999999999998 38624000.0 150253.0 127972.0 142346.0 132317.0 148025.0 143175.0 161123.0 123034.0 119002.0 110900.0 True False 175687.86526797796 140676.21442251597 145740.0684902112 124903.70746750176 119020.5638563535 135666.65095481728 145860.26301049782 119804.48786529842 120742.17912033427 131005.29211608335 1.3410745659976968 1.0738208521978123 1.1124746652300994 0.9534248994828775 0.90851722044091 1.0355814544850868 1.1133921435879974 0.9145011314439119 0.9216587908017108 1.0 16.999265566775236 -1.522882046089391 0.8343121827645769 0.9818930987184714 113.96539654466473 0.7109538657859887 0.06769028392982576 351.0767085651118 1.046343131283324 0.024985044971853113 75197.02290248682 0.029999771989054846 1.522882046089391 112.98350344594625 GPAFNMAS(ph)PESDFGINLK ddPTM_PC-9_Lapatinib_30min_R1 4 GPAFNMASPESDFGINLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GPAFNMAS(0.993)PES(0.007)DFGINLK;GPAFNMAS(0.919)PES(0.081)DFGINLK;GPAFNMAS(0.59)PES(0.41)DFGINLK;GPAFNMAS(0.991)PES(0.009)DFGINLK 193.47 2.1528e-14 50500000.0 121656.0 114865.0 122902.0 106407.0 134462.0 116643.0 126310.0 117729.0 124718.0 100851.0 True False 119921.16313102208 114599.03714978443 112797.47197543971 114232.52574334628 126553.20952246313 111654.4507981134 132849.71376042327 123199.11913084479 110670.945501237 118282.96097448962 1.0138498575199328 0.9688549915021175 0.9536240135193016 0.9657563929937728 1.069919187682131 0.9439605660716778 1.1231517427863114 1.0415626909899174 0.935645714221727 1.0 16.85188273840965 -6.2222642518959725 24.807551016478087 1.0225697579422448 0.9734810416054144 0.13286099733793666 0.053915711956833666 940.4279657011654 595522.9595605169 0.015771178652273937 0.020360139428084893 5.994262368986767e-07 6.2222642518959725 -0.04908871633683043 GPAFNMASPES(ph)DFGINLK ddPTM_PC-9_AZD4547_30min_R2 3 GPAFNMASPESDFGINLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GPAFNMAS(0.138)PES(0.862)DFGINLK;GPAFNMAS(0.034)PES(0.966)DFGINLK;GPAFNMAS(0.312)PES(0.688)DFGINLK 140.89 8.952799999999999e-05 88299000.0 133297.0 124200.0 144745.0 208286.0 187775.0 166688.0 134517.0 218688.0 152291.0 173065.0 True False 175682.67325016102 164345.22113662437 142825.5867252972 160268.88068662133 161705.68248243377 156264.97300946465 146488.75240604178 184894.79455030838 160340.79135176155 167006.04702688646 1.0519539644087121 0.9840674877489094 0.8552120672750465 0.9596591473170998 0.9682624393618551 0.935684520359358 0.8771463968754282 1.1071143700595583 0.9600897345109195 1.0 17.349540815805348 -7.75569911696585 24.999366282243177 1.0252015364938707 0.9461093836418757 0.23633017129971923 0.06166809829886664 190.84285784714183 831149.2420317867 0.029954745519417906 0.016679129073369315 1.755096026683115e-08 7.75569911696585 -0.079092152851995 GPAFNMASPES(ph)DFGINLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GPAFNMASPESDFGINLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GPAFNMAS(0.155)PES(0.845)DFGINLK;GPAFNMAS(0.071)PES(0.929)DFGINLK;GPAFNMAS(0.21)PES(0.79)DFGINLK 116.06 0.00010951 46704000.0 124167.0 115195.0 117094.0 125619.0 153053.0 124603.0 140423.0 122137.0 114382.0 103372.0 True False 145186.02068996348 126630.79830276678 119885.96504146777 118580.97469229321 123063.36335015364 118068.59932895476 127121.11686551955 118931.0331648483 116054.62036051588 122112.52530769815 1.18895273293321 1.0370008971944813 0.9817663236378095 0.9710795382659874 1.0077865725899908 0.966883610272136 1.0410161983400212 0.9739462259515709 0.950390797897942 1.0 16.89785166225208 -4.7545242921262565 2.445460075095035 0.9872640204432039 1.243604249468931 0.8650960791030964 0.024031357480091966 0.2003428134949088 1.4048798910210074 0.006258275797856786 0.11275403077909588 1.7598502243755397e-05 4.7545242921262565 0.25634022902572706 GPAFNMASPES(ph)DFGINLK ddPTM_PC-9_Lapatinib_30min_R1 2 GPAFNMASPESDFGINLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GPAFNMAS(0.004)PES(0.996)DFGINLK;GPAFNMAS(0.065)PES(0.935)DFGINLK 94.402 0.00084552 20490900.0 77425.0 69989.0 85595.0 60193.0 81170.0 91365.0 68848.0 69498.0 82118.0 71482.0 True False 76320.90530199402 69826.94477061146 78557.70950625505 64619.794017961656 76395.74018636002 87457.53193221752 72412.6125641487 72727.13079492247 72869.00609912426 83837.56845622222 0.9103425434129426 0.8328837066293646 0.9370227566568302 0.7707737140743105 0.9112351609559368 1.0431782975419372 0.8637251043601136 0.8674766233576857 0.8691688874203759 1.0 16.355309254499474 -6.498429831527329 24.943740756887692 0.9231256664904018 0.8628114669360811 0.17017409944563766 0.06855071969533194 1487.4950009894276 1517601.9531064136 0.02156132969301149 0.024320779775596782 3.173731398638904e-07 6.498429831527329 -0.06031419955432071 GPAGDATVAS(ph)EKESVM ddPTM_PC-9_Lapatinib_30min_R1 1 GPAGDATVASEKESVM 16 1 M0QXM4;Q15758-3;Q15758-2;Q15758 M0QXM4 SLC1A5 Amino acid transporter;Neutral amino acid transporter B(0) 1 GPAGDAT(0.01)VAS(0.811)EKES(0.179)VM 71.08 0.040451999999999995 4898400.0 68213.0 115060.0 36500.0 18466.0 39377.0 17888.0 15041.0 14342.0 44562.0 9793.9 True False 67240.27011126769 114793.58563926554 33499.11089407449 19824.051240770194 37060.922278160644 17122.971938964656 15819.749383821778 15008.381678045125 39542.95830133685 11486.762565448566 5.853718114930141 9.993554318303504 2.916323089574223 1.7258170984050503 3.226402745507902 1.490669963917374 1.3772156683560741 1.3065806481618556 3.442480688186199 1.0 13.48768462497498 -5.3721861075334605 5.419998498150807 1.9939980459350086 7.878741982940351 0.7916700384526791 1.2090368236327722 0.08246047867702282 3.376946993499531 0.2993287523854705 0.6401139162948359 4.244376413725581e-06 5.3721861075334605 5.884743937005343 GPAGDATVASEKES(ph)VM ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPAGDATVASEKESVM 16 1 M0QXM4;Q15758-3;Q15758-2;Q15758 M0QXM4 SLC1A5 Amino acid transporter;Neutral amino acid transporter B(0) 1 GPAGDATVAS(0.306)EKES(0.693)VM 78.40100000000001 0.021271 7451800.0 26585.0 29271.0 32058.0 21327.0 71893.0 24534.0 25860.0 25571.0 25615.0 23437.0 True False 31085.315422315674 32176.831434700238 32822.38430064205 20132.117333066908 57806.08273821878 23247.39385036139 23410.353589813192 24899.788344714067 25989.57091618098 27685.942572810072 1.1227833526189595 1.1622082704997228 1.1855252612160077 0.7271602648211205 2.0879217886910313 0.8396822246244304 0.8455682347908983 0.8993657441581113 0.9387280511700883 1.0 14.756866019061624 GPAGEAGAS(ph)PPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPAGEAGASPPVR 13 0 Q13425;Q13425-2;A0A140TA73 Q13425 SNTB2 Beta-2-syntrophin 1 GPAGEAGAS(1)PPVR 73.877 0.020269 13020000.0 16638.0 23141.0 26494.0 23470.0 22952.0 21158.0 22816.0 19469.0 16753.0 15089.0 True False 19454.484784520893 25438.285546458894 27125.717439054537 22155.051990766646 18454.720362310592 20048.437233469715 20654.703306464737 18957.959379110627 16997.980931437814 17824.516255541723 1.0914453164176283 1.4271515244375856 1.5218206794600122 1.2429538997378704 1.0353560286144055 1.1247675362430418 1.1587805812145446 1.0635889977219726 0.9536292984194208 1.0 14.12157530305165 -6.0775043900105326 4.283785908044928 1.0693901350665749 1.359185300453912 0.5635995299022406 0.11595286585167619 0.16859036311851106 5.744788623044286 0.03552992660900651 0.047775420765286174 8.365571394816276e-07 6.0775043900105326 0.2897951653873372 GPAGEAGAS(ph)PPVR ddPTM_PC-9_Lapatinib_30min_R1 2 GPAGEAGASPPVR 13 0 Q13425;Q13425-2;A0A140TA73 Q13425 SNTB2 Beta-2-syntrophin 1 GPAGEAGAS(1)PPVR;GPAGEAGAS(1)PPVR 84.169 0.008721 21804100.0 37231.0 49551.0 58136.0 47104.0 49894.0 54021.0 50711.0 54942.0 57591.0 38083.0 True False 36700.079112670806 49436.26770390435 53356.282491449674 50568.185294337614 46959.33301537816 51710.64775910161 53336.56744917136 57494.80589563207 51104.495119884436 44665.59580759222 0.8216632611544065 1.1068086479101935 1.1945722770898362 1.132150694063776 1.051353556721078 1.157728825153428 1.1941308849641552 1.2872280075095104 1.1441579183232957 1.0 15.44687638615402 -4.766409439130967 3.7264407867320135 1.1538509956072216 0.7808283298201394 0.6230808344877448 0.07475251011338245 0.17792252062564382 4.26863743225141 0.01916941020093088 0.1885720000917223 1.712342204106222e-05 4.766409439130967 -0.3730226657870822 GPAGEAGAS(ph)PPVRR ddPTM_PC-9_Lapatinib_30min_R1 1 GPAGEAGASPPVRR 14 1 Q13425;Q13425-2;A0A140TA73 Q13425 SNTB2 Beta-2-syntrophin 1 GPAGEAGAS(1)PPVRR 87.99 0.0027013000000000002 4799900.0 23478.0 20003.0 30166.0 21816.0 23332.0 23286.0 21708.0 18182.0 34057.0 26983.0 True False 23143.199414662107 19956.68428248066 27685.867924127426 23420.421416042595 21959.657632476938 22290.112062317257 22831.93402194023 19026.802096654334 30221.142023890963 31646.975597412522 0.7312926109929542 0.6306032063333196 0.8748345584843514 0.7400524370473324 0.6938943522385872 0.7043362482998127 0.7214570615653707 0.601220234713676 0.9549456607904695 1.0 14.949780011932893 -8.369957368825089 5.881531386003957 0.9940738153882405 0.7156996094986371 0.7032637188372157 0.06904272591628399 0.12804168419400813 5.665390390810491 0.06648273821744294 0.01727537134748857 4.266213947162829e-09 8.369957368825089 -0.2783742058896034 GPAPAPQQCS(ph)EPETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPAPAPQQCSEPETK 15 0 G3V154;Q3YEC7;Q3YEC7-2 G3V154 RABL6 Rab-like protein 6 1 GPAPAPQQCS(1)EPETK 130.47 1.223e-05 5536400.0 21728.0 19903.0 22586.0 31500.0 27248.0 23437.0 21939.0 16938.0 20282.0 14409.0 True False 25406.12125243841 21878.83830565539 23124.535897881997 29735.157124377885 21908.950001404643 22207.922461519498 19860.77909539487 16493.395447294453 20578.58588022576 17021.237638418756 1.492613039788251 1.2853846923723402 1.3585695934170758 1.7469444793639712 1.2871537585465465 1.304718430779313 1.166823442413316 0.9689892002956997 1.2089946875412685 1.0 14.055048320797367 -7.094506879283637 1.5740316366618472 1.0660408667173238 1.44469083929664 0.6075940888374991 0.13479650706847085 0.27982023009428153 1.3812309197265573 0.07119030403454611 0.04925074054504848 8.044390060279896e-08 7.094506879283637 0.3786499725793162 GPAPAPQQCS(ph)EPETK ddPTM_PC-9_Lapatinib_30min_R1 1 GPAPAPQQCSEPETK 15 0 G3V154;Q3YEC7;Q3YEC7-2 G3V154 RABL6 Rab-like protein 6 1 GPAPAPQQCS(0.848)EPET(0.152)K 193.54 1.5059e-09 7570400.0 13750.0 26471.0 23936.0 28042.0 30183.0 30778.0 29139.0 26283.0 29170.0 21949.0 True False 13553.922478558823 26409.708025873377 21968.074475631976 30104.302225369724 28407.695282061148 29461.69668702225 30647.674841778004 27504.204130808816 25884.567426282392 25742.85540479588 0.5265120075232111 1.025904376596594 0.8533658807538241 1.169423583825177 1.1035176492802274 1.1444611028477265 1.1905312895502789 1.0684208763292358 1.0055049068667072 1.0 14.651884466125292 -4.485020824728688 1.2520288601815694 1.0935649770835274 1.7798603977875777e-27 0.7310085422230614 0.0965985205213762 1.3933203755526398 1.1677786847895215 0.028170421325730284 2.3486599071361347 3.273249990364751e-05 4.485020824728688 -1.0935649770835274 GPAPAPQQCSEPET(ph)K ddPTM_PC-9_AZD4547_30min_R2 2 GPAPAPQQCSEPETK 15 0 G3V154;Q3YEC7;Q3YEC7-2 G3V154 RABL6 Rab-like protein 6 1 GPAPAPQQCS(0.425)EPET(0.575)K;GPAPAPQQCS(0.074)EPET(0.926)K 163.9 0.00062545 14964500.0 32877.0 34565.0 43185.0 44584.0 44703.0 50341.0 39954.0 42804.0 41407.0 37437.0 True False 43331.20211591813 45737.46029458476 42612.33868342227 34305.847615933526 38496.76007994797 47193.16931194482 43509.82859884613 36189.625338068014 43595.68948593407 36126.342024935955 1.1994350849584792 1.2660418334913288 1.1795364904093917 0.949607563153063 1.0656146712383958 1.3063367799421834 1.204379579001211 1.0017517221391632 1.2067562626695625 1.0 15.140763561536678 -14.52287874528033 0.14169550272119044 0.5053226411385379 1.2002317712862272 0.1542934908336151 0.10791536778804142 300.3634089548653 2.5848344941971466 42.3649385109359 0.6944196943262108 3.0000000000000503e-15 14.52287874528033 0.6949091301476893 GPAPAPQQCSEPET(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 GPAPAPQQCSEPETK 15 0 G3V154;Q3YEC7;Q3YEC7-2 G3V154 RABL6 Rab-like protein 6 1 GPAPAPQQCS(0.304)EPET(0.696)K 178.85 8.404e-05 6069200.0 12634.0 21411.0 20128.0 21589.0 24675.0 26098.0 19790.0 22526.0 23619.0 16937.0 True False 12453.836843208159 21361.424144987926 18473.15353632687 23176.727078792792 23223.66501291652 24981.8493774094 20814.629366786325 23572.64019520599 20958.77950090379 19864.537882866094 0.626938160688352 1.0753546984555302 0.9299563697507736 1.1667387993346467 1.1691017002186495 1.2576103972173034 1.0478285218373855 1.186669447545431 1.0550851786480027 1.0 14.277907611341828 -4.4087928944255745 1.3195842283405148 1.125313226423581 5.264842184479828e-31 0.6822646162414254 0.09534957770843291 1.7788718249168438 1.4286512472905115 0.02692715607669646 3.416613056131543 3.901279858584628e-05 4.4087928944255745 -1.125313226423581 GPAPEACCLFS(ph)APR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPAPEACCLFSAPR 14 0 B1ANH6 B1ANH6 GUK1 1 GPAPEACCLFS(1)APR 93.766 0.016537 0.0 1805.3 2672.4 2820.6 4843.8 4919.9 2452.8 6997.8 3053.5 4675.2 1732.4 True False 2110.9016336996983 2937.6982107236818 2887.8538011850683 4572.417589811482 3955.8809127976633 2324.1708500923783 6334.917724315345 2973.348860450683 4743.565955390564 2046.470406329146 1.0314840748106031 1.43549508541058 1.4111388037929915 2.2342945080809895 1.9330261999212195 1.1356972682841562 3.0955335121012557 1.4529156401455734 2.3179255076057173 1.0 10.998922089019004 -5.618190201231569 5.998898345606437 1.9206045184604328 1.2786681480759878 0.17681047480576761 0.5836893207120856 0.3275978193673372 16.937583627611353 0.15086435596306785 0.26448800693331526 2.4088502307913804e-06 5.618190201231569 -0.641936370384445 GPASQFYITPSTSLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 GPASQFYITPSTSLSPR 17 0 H0YIQ2;P49750-3;P49750-1;P49750 H0YIQ2 YLPM1 YLP motif-containing protein 1 1 GPASQFYITPSTS(0.003)LS(0.997)PR;GPASQFYITPSTSLS(1)PR;GPASQFYITPSTSLS(1)PR;GPASQFYITPSTS(0.006)LS(0.994)PR 183.39 4.0587e-08 93547700.0 153272.0 142409.0 212882.0 256912.0 230904.0 199736.0 177389.0 217227.0 174537.8 201637.0 True False 202009.30774435017 188439.92429022162 210059.04558537237 197684.90765083244 198846.96529316364 187246.4763451384 193176.2773519725 183659.5585298683 183763.51178201925 194577.75000352654 1.0381932556044509 0.9684556650840414 1.0795635450690804 1.0159687202018195 1.0219409222768776 0.9623221377662385 0.9927973642848238 0.9438877699353583 0.9444220203938463 1.0 17.569987221581428 -6.756963071728668 22.56480479716896 0.9666857997608451 1.0242419417899329 0.4588320753353766 0.03044188904612528 30.253941994629816 152507.4120304896 0.01006661390831303 0.009717576686288877 1.7499954852669397e-07 6.756963071728668 0.057556142029087765 GPASQFYITPSTSLS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GPASQFYITPSTSLSPR 17 0 H0YIQ2;P49750-3;P49750-1;P49750 H0YIQ2 YLPM1 YLP motif-containing protein 1 1 GPASQFYITPSTS(0.001)LS(0.999)PR;GPASQFYITPSTSLS(1)PR;GPASQFYITPS(0.001)T(0.001)S(0.086)LS(0.913)PR;GPASQFYITPSTS(0.005)LS(0.995)PR 206.45 2.5651999999999996e-17 82173000.0 279609.0 293750.0 330448.0 370771.0 377606.0 304236.0 309538.0 281497.0 277192.0 244142.0 True False 326941.2811705203 322911.55867388187 338327.1335510185 349997.9029258007 303616.814967351 288281.32858313154 280216.3197789479 274108.0020207254 281245.40860425675 288403.0119729911 1.133626444931644 1.1196539053625503 1.1731054098100153 1.2135722873746477 1.052751886640437 0.9995780786440921 0.9716137077139476 0.9504339089440423 0.9751819396067727 1.0 18.137726706060647 -6.544699282243623 2.876613882610803 0.9750429758301132 1.1576382591119296 0.9013107977474941 0.02803852063284712 0.08119050452722902 1.370371459224664 0.010511450898349057 0.011056319637979711 2.8529930766446005e-07 6.544699282243623 0.1825952832818164 GPASQFYITPSTSLS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 GPASQFYITPSTSLSPR 17 0 H0YIQ2;P49750-3;P49750-1;P49750 H0YIQ2 YLPM1 YLP motif-containing protein 1 1 GPASQFYITPS(0.007)T(0.001)S(0.015)LS(0.976)PR;GPASQFYITPST(0.002)S(0.088)LS(0.909)PR;GPASQFYITPST(0.002)S(0.024)LS(0.973)PR;GPASQFYITPSTS(0.001)LS(0.999)PR 178.57 3.2686e-06 71640600.0 187554.0 177235.0 205038.0 151778.0 162587.0 180946.0 150851.0 154490.0 193103.0 126529.0 True False 184879.44556680915 176824.6232467862 188180.56710956874 162940.26043656524 153023.95231834083 173207.36138572774 158661.3266603883 161668.16939347278 171353.70667526228 148399.36906070507 1.2458236631126198 1.191545653906745 1.2680685120203614 1.097984859827214 1.0311630924505077 1.16717047034664 1.0691509516828566 1.0894127813127015 1.1546794825331594 1.0 17.17912543260222 -1.5228787452847161 0.2303170828520595 1.046127752582775 2.252335669147222 0.5276633312433561 0.05802335596812876 42.564008554612144 0.5575076202538898 0.08701921933211311 19.362907441720044 0.02999999999969754 1.5228787452847161 1.206207916564447 GPASTPT(ph)YSPAPTQPAPR ddPTM_PC-9_AZD4547_30min_R2 1 GPASTPTYSPAPTQPAPR 18 0 Q6P1N0;Q6P1N0-2;K7EJY5 Q6P1N0 CC2D1A Coiled-coil and C2 domain-containing protein 1A 1 GPAS(0.006)T(0.006)PT(0.494)YS(0.494)PAPTQPAPR 243.86 6.1096e-53 10642000.0 12348.0 10266.0 16148.0 23105.0 17689.0 15873.0 10696.0 19961.0 15840.0 15883.0 True False 16274.407145644584 13584.283737428232 15933.86696908423 17778.499218691544 15233.187684365692 14880.458800748906 11647.92327910242 16876.486108148198 16677.270061999083 15326.941004408953 1.0618170410496839 0.8863010390345061 1.0395986364468088 1.1599509134652097 0.9938831029612307 0.9708694511493446 0.759963992537831 1.1010994368213136 1.0881016673321633 1.0 13.903782167991707 -6.5081747306235025 24.552983702529872 0.9769955168448249 1.0326710271830697 0.05058456374501663 0.10674155792539537 1938.03543038371 3236167.3693181025 0.035944149595564065 0.03932295534375737 3.1033107752953693e-07 6.5081747306235025 0.055675510338244805 GPASTPTYS(ph)PAPTQPAPR ddPTM_PC-9_AZD4547_30min_R2 1 GPASTPTYSPAPTQPAPR 18 0 Q6P1N0;Q6P1N0-2;K7EJY5 Q6P1N0 CC2D1A Coiled-coil and C2 domain-containing protein 1A 1 GPAS(0.001)TPT(0.146)YS(0.851)PAPT(0.001)QPAPR 232.01 7.0388e-36 10986000.0 8303.7 9145.0 12269.0 14982.0 15363.0 9788.3 6747.7 13895.0 8938.6 10838.0 True False 10944.103872310408 12100.942409778025 12106.305043577815 11528.13136959259 13230.112634683135 9176.236053636396 7348.232227973014 11747.847025335364 9411.07614748643 10458.564918830461 1.0464250073741708 1.157036601454803 1.1575493518982347 1.1022670375011385 1.2650026784136084 0.8773895964555084 0.7026042564159689 1.1232752405813893 0.8998439289258466 1.0 13.352397284047795 -6.774606024547721 24.99829796435548 0.9147011167477166 1.144538617627548 0.505581495620838 0.11118782852523419 195.66288410997674 371484.8703830039 0.039306556900666256 0.03486838552126225 1.6803276563278512e-07 6.774606024547721 0.22983750087983146 GPCAPAASS(ph)PTQK ddPTM_PC-9_AZD4547_30min_R2 4 GPCAPAASSPTQK 13 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 GPCAPAAS(0.293)S(0.706)PT(0.001)QK;GPCAPAAS(0.114)S(0.652)PT(0.235)QK;GPCAPAAS(0.03)S(0.634)PT(0.336)QK;GPCAPAAS(0.029)S(0.95)PT(0.022)QK 149.49 7.2869e-05 51947200.0 433361.0 428615.0 491947.0 555668.0 526015.0 523245.0 505152.0 577857.0 514159.0 519847.0 True False 571160.783531234 567156.4167268467 485423.46134753985 427567.3275850199 452986.8969298218 490526.4074338723 550109.5493909075 488562.47848285123 541336.395063598 501647.31475911144 1.1385703994159773 1.1305879649713513 0.9676588452997855 0.8523265549429596 0.9029987475311093 0.9778312232557661 1.0966061876660647 0.9739162636950554 1.0791174977654274 1.0 18.936313902220093 -5.258188385153008 22.590053650255744 0.9769658826669204 1.1345792674932829 0.4464711767189192 0.06812778837995262 69.03838843537049 479696.4522842485 0.019413233903578304 0.04693139960126449 5.518380150108561e-06 5.258188385153008 0.15761338482636245 GPCAPAASS(ph)PTQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GPCAPAASSPTQK 13 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 GPCAPAAS(0.116)S(0.637)PT(0.247)QK;GPCAPAAS(0.113)S(0.606)PT(0.281)QK;GPCAPAAS(0.049)S(0.944)PT(0.007)QK 152.0 4.4127e-05 29495400.0 245745.0 235765.0 246159.0 294263.0 307019.0 255592.0 297646.0 294013.0 241410.0 200209.0 True False 287344.7748150065 259170.19108339626 252028.3641232065 277776.39812351763 246860.83090433208 242188.30557599937 269450.81610957254 286295.4702825237 244940.1645471502 236505.30684642744 1.2149612143865811 1.095832455259391 1.0656351330283629 1.1745038698175563 1.0437855885602978 1.0240290537466128 1.1393013531173657 1.2105245083080824 1.035664559976237 1.0 17.851513030412164 -14.296539109128199 0.34000737569854195 1.4736145369055589e-15 1.1145626164010327 0.20784544809086802 0.06707453122044155 580.0517623968381 5.704035905056801 418.55645436863557 0.05491497455256651 5.051971488297381e-15 14.296539109128199 1.1145626164010312 GPCAPAASS(ph)PTQK ddPTM_PC-9_Lapatinib_30min_R1 4 GPCAPAASSPTQK 13 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 GPCAPAAS(0.194)S(0.403)PT(0.403)QK;GPCAPAAS(0.036)S(0.711)PT(0.253)QK;GPCAPAAS(0.034)S(0.961)PT(0.005)QK;GPCAPAAS(0.397)S(0.602)PT(0.001)QK 230.81 4.8324000000000004e-20 49667400.0 357443.0 471049.0 505731.0 452652.0 558979.0 516721.0 502880.0 480305.0 520091.0 424071.0 True False 352345.7972729813 469958.314981665 464151.7493581142 485941.5380828077 526100.9542149971 494622.0473654822 528916.6657892618 502621.72373960895 461512.8747789721 497371.10731091123 0.7084162953855032 0.9448846305579423 0.9332101172253432 0.9770200378347292 1.0577634013753168 0.9944728193796939 1.063424589837767 1.0105567379196707 0.9279044721238224 1.0 18.923963177106323 -4.159375242678664 1.0958912492216264 1.0067280188941463 1.4331899526201494e-19 0.8141746559706937 0.04115077901017511 2.3364987733821665 0.8861615598400713 0.01284951567993426 3.79326905885755 6.928269253290069e-05 4.159375242678664 -1.0067280188941463 GPCIIYNEDNGIIK ddPTM_PC-9_Lapatinib_30min_R1 1 GPCIIYNEDNGIIK 14 0 P36578;H3BM89 P36578 RPL4 60S ribosomal protein L4 0 142.1 0.0006662 5350200.0 51387.0 44895.0 36022.0 32051.0 38491.0 36805.0 34196.0 27239.0 39923.0 27388.0 False True 50654.211956778345 44791.04838584057 33060.410208941124 34408.13745900169 36227.03505621763 35230.93594664547 35966.50155768698 28504.623380858386 35426.4513321725 32121.979307783935 1.5769330859541273 1.3944049946818382 1.0292146038749792 1.0711711482443975 1.1277958530855208 1.0967859610727089 1.1196850982645215 0.8873868919388483 1.1028726154364907 1.0 14.971273171830129 -5.10095435187621 2.8759481878366073 1.0562060866899197 1.5644435792622897 0.8651281675364673 0.06966707306823994 0.09390972226142733 1.4243793598683874 0.01896495386299582 0.07680573247836292 7.925846336345027e-06 5.10095435187621 0.50823749257237 GPDGLTAFEATDNQAIK ddPTM_PC-9_Lapatinib_30min_R1 2 GPDGLTAFEATDNQAIK 17 0 C9JL85;P58546 C9JL85 MTPN Myotrophin 0 ; 214.65 1.3165999999999998e-21 6775700.0 28641.0 32830.0 35479.0 30289.0 28406.0 26371.0 34697.0 26788.0 32983.0 23236.0 False True 28232.574087883866 32753.984152069188 32562.053572900524 32516.554101141992 26735.214928344743 25243.173803803485 36493.440886275115 28032.668274401945 29268.107213612348 27252.31163997619 1.0359698825133696 1.201879113404187 1.194836386838301 1.1931668230831372 0.9810255835004866 0.9262764251812857 1.3390952433093122 1.0286345116236326 1.0739678747354116 1.0 14.73409098925857 -14.522878675617521 0.0963246638327569 0.6272735513055893 1.19534603566767 0.08246896859833541 0.11706590717420554 532.5296039289292 3.504855465425072 39.748685686454586 2.3131678517111474 3.0000004812137246e-15 14.522878675617521 0.5680724843620807 GPDWHLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPDWHLK 7 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 79.116 0.022945 3836200.0 58069.0 59854.0 68075.0 68438.0 85941.0 68492.0 68265.0 65118.0 62305.0 62801.0 False True 67898.9347849708 65795.90955869447 69698.1661758753 64603.6407389897 69101.4779826306 64900.158946725045 61798.445004199464 63408.721498224135 63216.092755520425 74186.32416755742 0.9152486734834588 0.886900790637472 0.9395015450348347 0.8708295156001495 0.9314584427523033 0.8748264545381892 0.8330166738632492 0.854722514017665 0.8521259607463553 1.0 16.178865638173214 -6.888593197653645 8.171076530647616 0.8702178112774369 0.9070887749698794 0.03749714360702727 0.04714901080847558 0.5140669999114459 35.04481617682686 0.015552257181480077 0.013719598871166113 1.2924293214930198e-07 6.888593197653645 0.03687096369244247 GPEEEEIGSPEPMAAPAS(ph)ASQKLSPLQK ddPTM_PC-9_AZD4547_30min_R2 1 GPEEEEIGSPEPMAAPASASQKLSPLQK 28 1 H3BRB3;Q14807-2;Q14807 H3BRB3 KIF22 Kinesin-like protein;Kinesin-like protein KIF22 1 GPEEEEIGSPEPMAAPAS(0.809)AS(0.068)QKLS(0.123)PLQK 69.07 0.00028525 9924900.0 56486.0 40129.0 63425.0 94167.0 82593.0 65555.0 67210.0 69162.0 71618.0 84095.0 True False 74447.37301821182 53099.914484634464 62583.94305884119 72458.25301564719 71126.38760895559 61455.83548687041 73191.55979697757 58474.60208465236 75403.58126895518 81150.8596465257 0.9173947551817354 0.65433582239209 0.7712049303167251 0.8928833697049978 0.8764711540797672 0.7573035671409737 0.9019197099794507 0.7205666377331571 0.9291778497158955 1.0 16.308318757147227 -14.522878742330198 0.18362342920552674 1.7724839294401282 0.7823908001594415 0.2856640649736407 0.08773859197174522 172.25007650046206 1.6637305345855877 48.334624576344176 0.253634149495386 3.0000000203788444e-15 14.522878742330198 -0.9900931292806867 GPEEEEIGSPEPMAAPASASQKLS(ph)PLQK ddPTM_PC-9_Lapatinib_30min_R1 1 GPEEEEIGSPEPMAAPASASQKLSPLQK 28 1 H3BRB3;Q14807-2;Q14807 H3BRB3 KIF22 Kinesin-like protein;Kinesin-like protein KIF22 1 GPEEEEIGSPEPMAAPAS(0.142)AS(0.422)QKLS(0.436)PLQK 77.19 3.4653e-05 8775200.0 25171.0 17505.0 21934.0 22955.0 21662.0 22447.0 17258.0 11001.0 22440.0 17090.0 True False 24812.056924203942 17464.468248003996 20130.6711876885 24643.187275635202 20387.883749130597 21486.994136512727 18151.534795957472 11512.146621124983 19912.57089632419 20043.983729006413 1.2378805161519597 0.8713072453122429 1.0043248617567293 1.2294555617690461 1.0171572689727597 1.071992196113095 0.905585189120349 0.5743442409836582 0.9934437767232842 1.0 14.290881651301495 -7.380741704625987 4.270889125078033 0.8224535923621525 1.0641514051232521 0.2996549279486074 0.14982979951173384 0.25806187888691556 7.7898855228413835 0.06386656983927458 0.04171720521312309 4.1615804568762114e-08 7.380741704625987 0.24169781276109958 GPESESEDHR ddPTM_PC-9_AZD4547_30min_R2 2 GPESESEDHR 10 0 P78527-2;P78527 P78527-2 PRKDC DNA-dependent protein kinase catalytic subunit 0 ; 166.66 0.00027725 11403600.0 44393.0 34962.0 83568.0 121239.0 100323.0 92532.0 65436.0 94772.0 68621.0 93223.0 False True 58509.050568237726 46262.7827808266 82459.83371763877 93289.22167387769 86394.88315103289 86745.95941226577 71259.67723367104 80127.16504390647 72248.16596745203 89959.29114487265 0.6503947488204783 0.514263531782658 0.9166349875394575 1.0370159711868165 0.9603775446818544 0.9642801572609987 0.792132489338013 0.8907047179247746 0.8031206676706891 1.0 16.45698467265933 -5.268890899550945 24.80480823142288 0.9191896732549518 0.5823291345068361 0.7413608359302923 0.07990135299711663 228.82611323131377 761724.2563833558 0.021934701862743555 0.04716399693933268 5.384050199055572e-06 5.268890899550945 -0.3368605387481157 GPESESEDHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GPESESEDHR 10 0 P78527-2;P78527 P78527-2 PRKDC DNA-dependent protein kinase catalytic subunit 0 ; 184.71 1.9758999999999999e-28 0.0 35113.1 43898.0 52783.0 64492.0 75592.0 62783.0 65289.0 54350.0 60079.0 48150.0 False True 41057.05431466286 48255.90332822487 54041.54690064225 60878.72232588504 60780.29024171233 59490.54895684514 59104.35326857363 52923.37008858507 60957.54171669872 56879.21384480972 0.7218287936729167 0.8483925860840333 0.9501106511086843 1.0703158185692871 1.0685852727772642 1.0459101829213082 1.039120432111369 0.9304518559799746 1.071701551343807 1.0 15.795613904456982 -5.108299697610171 1.6608469500792682 1.0313158616849059 0.7034307261788337 0.8492204405630286 0.04248100156249074 0.2032394753201576 0.8433530395598721 0.012699251338827672 0.0874067586407191 7.792921515842831e-06 5.108299697610171 -0.3278851355060721 GPESESEDHR ddPTM_PC-9_Lapatinib_30min_R1 1 GPESESEDHR 10 0 P78527-2;P78527 P78527-2 PRKDC DNA-dependent protein kinase catalytic subunit 0 169.99 1.6611e-19 0.0 27989.0 29269.0 44814.0 26711.0 31524.0 42632.0 28594.0 37000.0 52688.0 24327.0 False True 27589.871727446025 29201.229428782004 41129.56590704256 28675.416045283888 29669.82029856861 40808.72874004592 30074.457408483457 38719.1550751408 46753.72261076333 28531.889536310075 0.9669836865285342 1.0234593608537603 1.4415296910041835 1.0050303891998165 1.0398827690963262 1.4302848287742096 1.0540646938300489 1.357048401083506 1.6386479609513385 1.0 14.800287672715001 -7.0139782177003 1.1311888409445015 1.3297817807475187 1.1081417090997026 0.12794439220082232 0.21673709830689852 0.9994836285953024 2.6200745892828774 0.13059285584841385 0.0925864365942314 9.683264220346339e-08 7.0139782177003 -0.22164007164781618 GPFVEAEVPDVDLECPDAK ddPTM_PC-9_Lapatinib_30min_R1 1 GPFVEAEVPDVDLECPDAK 19 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 155.98 5.0234e-20 0.0 7558.9 6136.8 8367.5 6753.5 7941.1 8406.8 7271.6 5801.1 6383.4 6285.2 False True 7451.108699867511 6122.590616643864 7679.556449484063 7250.17491901557 7474.0201108033 8047.260761207961 7648.087867787947 6070.640283956738 5664.434271817999 7371.5884454974275 1.010787397446022 0.8305659847822281 1.041777699102931 0.9835295299812868 1.0138954671795923 1.0916589851300278 1.037508798047374 0.823518611875937 0.7684143402332559 1.0 12.84775981246549 -7.7647295929436515 24.999949856633794 0.846974821708939 0.9996384377343797 0.35318905560923575 0.08425490142872191 88.75787638420415 674383.8159914509 0.04438588762219852 0.022706845621656934 1.7189783505516086e-08 7.7647295929436515 0.15266361602544065 GPGAPAAS(ph)SPTQK ddPTM_PC-9_AZD4547_30min_R2 4 GPGAPAASSPTQK 13 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 GPGAPAAS(0.496)S(0.496)PT(0.008)QK;GPGAPAAS(0.901)S(0.076)PT(0.023)QK;GPGAPAAS(0.755)S(0.239)PT(0.007)QK;GPGAPAAS(0.689)S(0.272)PT(0.039)QK 195.72 1.0962e-06 124829000.0 163264.0 184224.0 188684.0 164004.0 171994.0 183032.0 181849.0 209123.0 194834.0 174572.0 True False 215178.5558978394 243770.80530332908 186181.92687606456 126195.41163654138 148115.60193254505 171586.9801057567 198033.20871180765 176807.84551847496 205132.5274785057 168460.287415581 1.2773251144170694 1.4470520562627425 1.105197727798988 0.7491107463518994 0.8792315637403201 1.018560414078259 1.1755483250676886 1.0495520827546796 1.2176907129005223 1.0 17.36204900708327 -5.402690188412271 5.050576788206438 1.0105201589732582 1.3572534669468266 0.5210774636145454 0.13164503773558642 0.18084195941241782 6.6468653340905135 0.03808361924755115 0.08162451676762768 3.956487624063123e-06 5.402690188412271 0.3467333079735684 GPGAPAAS(ph)SPTQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GPGAPAASSPTQK 13 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 GPGAPAAS(0.673)S(0.322)PT(0.005)QK;GPGAPAAS(0.499)S(0.499)PT(0.002)QK;GPGAPAAS(0.463)S(0.463)PT(0.074)QK;GPGAPAAS(0.431)S(0.431)PT(0.138)QK 151.16 0.000132 85412000.0 130910.0 170914.0 157805.0 142928.0 169538.0 145407.0 188606.0 153247.0 142434.0 125259.0 True False 153070.47740964216 187881.21238872426 161567.6696787953 134920.2075388282 136318.24593871593 137781.6009456058 170739.87429080813 149224.42862861828 144516.82779134603 147967.46515030184 1.0344873939291777 1.26974677979297 1.0919134791873246 0.9118234701241887 0.9212717525453794 0.9311614604308489 1.1539014614961107 1.0084948639015991 0.9766797562190396 1.0 17.174920467681247 -5.547315619654733 7.977783610050938 0.9892677240106793 1.1593502376691571 0.40287518881780326 0.08338617664903472 0.1740591895394379 46.07888098186932 0.0232318828044181 0.04099544528838681 2.8358573452566404e-06 5.547315619654733 0.17008251365847782 GPGAPAAS(ph)SPTQK ddPTM_PC-9_Lapatinib_30min_R1 3 GPGAPAASSPTQK 13 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 GPGAPAAS(0.6)S(0.395)PT(0.005)QK;GPGAPAAS(0.739)S(0.254)PT(0.008)QK;GPGAPAAS(0.706)S(0.266)PT(0.028)QK 164.22 6.0506000000000007e-05 74448000.0 46979.0 102903.0 106017.0 93091.0 137741.0 127485.0 154606.0 139514.0 118169.0 116252.0 True False 46309.070845106515 102664.73442584167 97300.69149745465 99937.22268247268 129639.34518922532 122032.76373204993 162610.74218703207 145996.3297608974 104859.56284526431 136346.00330394693 0.3396437718960697 0.7529720852688151 0.7136306832591843 0.732967745740881 0.9508114799685701 0.8950226686147195 1.1926329943425986 1.0707782129516306 0.7690695752299243 1.0 17.05691288574181 -4.708003255672042 0.5407056688371839 1.0126218110803231 7.059995516934791e-12 0.6875353308612281 0.1260968720252546 2.6931112873003826 0.5677101824364162 0.07458781151167912 1.7581986260962639 1.9588299891565427e-05 4.708003255672042 -1.0126218110732632 GPGAPAAS(ph)SPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPGAPAASSPTR 12 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 GPGAPAAS(0.746)S(0.222)PT(0.033)R 111.52 0.0020255 0.0 22273.0 37167.0 35173.0 24502.0 36437.0 25917.0 28849.0 26778.0 33207.0 23576.0 True False 26043.37898819775 40856.69413185416 36011.65771434533 23129.232376555774 29297.431415193085 24557.866895729036 26116.21387132716 26075.10587363626 33692.58955352806 27850.1421724867 0.9351255310260549 1.4670192302363432 1.2930511266804747 0.8304888439458403 1.051967032474835 0.8817860513469795 0.9377407738021353 0.9362647311508518 1.2097815998516928 1.0 14.765397071962798 -5.747904579162034 24.99942774156609 0.9729935671304151 1.2552607855796907 0.3537693294576032 0.15588756287636663 226.58854811536807 418516.36279765837 0.04075774127595441 0.07009886851459095 1.7868801353773477e-06 5.747904579162034 0.2822672184492756 GPGAPAAS(ph)SPTRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPGAPAASSPTRK 13 1 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 GPGAPAAS(0.418)S(0.418)PT(0.163)RK 61.409 0.024547 17338000.0 14262.0 16463.0 22661.0 17485.0 20329.0 20483.0 20306.0 18639.0 17656.0 12240.0 True False 16676.274912660003 18097.337839823373 23201.324182321066 16505.372137134855 16345.678382947543 19408.835421739295 18382.468677291065 18149.74599965294 17914.18559812966 14459.015108213318 1.1533479139382867 1.251630052557545 1.6046268717944527 1.1415281064170908 1.1304835260641315 1.3423345419090318 1.2713499875139533 1.255254653502861 1.238963059659137 1.0 13.819681664418813 -13.31929097390681 0.30378497877633526 1.3288298822765296e-07 1.2847664237696739 0.2763316646501587 0.12945128895443977 172.5528508100634 3.149562969980952 108.19435286360155 0.13220923245732374 4.794121386271045e-14 13.31929097390681 1.2847662908866857 GPGAPAASS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 2 GPGAPAASSPTR 12 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 GPGAPAAS(0.117)S(0.765)PT(0.117)R;GPGAPAAS(0.107)S(0.891)PT(0.002)R 105.25 0.0018131 7448600.0 47491.0 74744.0 77440.0 74541.0 71175.0 80119.0 66082.0 100741.0 77703.0 63398.0 True False 62592.150125834654 98903.53630141586 76413.09500160294 57356.72409696976 61293.57981992926 75109.14626454988 71963.1699822034 85173.79324788107 81810.22194618144 61178.45531684934 1.023107723162732 1.6166399721794962 1.2490196852119244 0.937531420169299 1.0018817817887635 1.2277058300271249 1.1762828860176175 1.3922187607836367 1.3372390905013558 1.0 15.900736060573474 -11.86894760543663 1.8990151019930368 0.0001347775966474567 1.2201812353953614 0.10356911783250444 0.19227012399183252 6123806.146388796 661476.2420168845 26248537.0396408 0.05379930161100418 1.352235691044081e-12 11.86894760543663 1.220046457798714 GPGAPAASS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPGAPAASSPTR 12 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 GPGAPAAS(0.166)S(0.806)PT(0.028)R 89.35600000000001 0.026724 0.0 19621.0 29438.0 32728.0 24677.0 33774.0 23629.0 26439.0 24940.0 20195.0 18230.0 True False 22942.447767585323 32360.410091035676 33508.3596416312 23294.427693913443 27156.22714868762 22389.853643522823 23934.506518216192 24285.351426114292 20490.313669813586 21534.95469139939 1.0653585343621854 1.5026922765692998 1.55599861350132 1.0817031207043473 1.2610301501833783 1.0396982006405084 1.1114259055197888 1.1277177859962413 0.9514909115642108 1.0 14.394392667765294 -6.229975088959972 1.45274870644703 1.0620072187607372 1.3696981090463938 0.4030996601932655 0.15170285230640052 0.4043985928983862 1.7106782934107454 0.056654273110739096 0.08058832543178092 5.888774322723699e-07 6.229975088959972 0.30769089028565655 GPGAPAASS(ph)PTRK ddPTM_PC-9_Lapatinib_30min_R1 1 GPGAPAASSPTRK 13 1 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 GPGAPAAS(0.127)S(0.436)PT(0.436)RK 52.00899999999999 0.043648 21193000.0 17028.0 28395.0 30784.0 27829.0 38874.0 35215.0 37614.0 39603.0 44136.0 28396.0 True False 16785.17759744725 28329.25312208359 28253.058349676405 29875.637494822582 36587.50774922459 33708.93654017442 39561.4688732845 41443.09995785953 39164.9389073157 33304.210764708354 0.5039956573669684 0.8506207615075329 0.8483329195002414 0.8970528593483756 1.0985850410241658 1.012152390528796 1.1878818913555163 1.2443801851559189 1.175975590114203 1.0 15.023416973221812 -4.5364047178494555 0.47926230164043715 1.1695880630560407 1.4713128999561475e-14 0.8182836167681902 0.08885848378531902 2.365766456502941 0.3527434074801078 0.05819497178504916 1.6446208611253912 2.9080058921692208e-05 4.5364047178494555 -1.169588063056026 GPGAPAASSPT(ph)QK ddPTM_PC-9_Lapatinib_30min_R1 1 GPGAPAASSPTQK 13 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 GPGAPAAS(0.286)S(0.286)PT(0.428)QK 75.378 0.045057 33585000.0 17679.0 34436.0 36452.0 35056.0 44359.0 44504.0 53969.0 64366.0 50047.0 46728.0 True False 17426.89421806846 34356.26555774153 33455.05726878914 37634.135183387814 41749.890833149475 42600.66766389102 56763.25074765492 67356.67933963543 44410.17984172624 54804.87253885381 0.3179807453381759 0.6268834132108367 0.6104394685905207 0.6866932343781508 0.7617915871175682 0.7773153314732985 1.0357336513721973 1.2290272054165083 0.8103326909526471 1.0 15.742016544179444 -6.043962062999507 0.530139757787178 1.0558680070635187 0.3520050631997038 0.738519534043182 0.12428385295904984 0.7107549506052824 0.3625868242318984 0.09573017456029645 0.26844425080985845 9.037284138178184e-07 6.043962062999507 -0.7038629438638149 down GPGAPAASSPT(ph)RK ddPTM_PC-9_AZD4547_30min_R2 1 GPGAPAASSPTRK 13 1 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 GPGAPAAS(0.285)S(0.285)PT(0.429)RK 95.264 0.012136 9340700.0 9656.1 9444.1 14978.0 15909.0 13116.0 15299.0 11597.0 15989.0 11502.0 12998.0 True False 12726.53894064291 12496.720635558737 14779.381933548655 12241.425841599814 11295.069798639857 14342.35111148853 12629.110533634137 13518.267440668382 12109.972238201612 12542.943976283295 1.0146373104039021 0.9963147933362407 1.1783024751999296 0.9759611351805761 0.9005118590975956 1.1434597123775427 1.0068697235285249 1.0777587356069889 0.9654808521109267 1.0 13.614588384906666 -8.278892740582599 24.583059544801667 0.9827404207036067 1.0360955663278448 0.07322826357158607 0.07679692749575823 2252.057582734915 3171987.5102380887 0.07280184951777736 0.018993354822185164 5.261471949890039e-09 8.278892740582599 0.053355145624238154 GPGAPAASSPT(ph)RK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPGAPAASSPTRK 13 1 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 GPGAPAAS(0.193)S(0.193)PT(0.614)RK 94.781 0.012551999999999999 1381500.0 7123.9 7620.0 14263.0 10158.0 12002.0 9259.6 12017.0 11959.0 11075.0 9515.5 True False 8329.83556656139 8376.463241174399 14603.084012728723 9588.88019268034 9650.294257077896 8774.010275405819 10878.662764454179 11645.088921607892 11236.950923158476 11240.584825343443 0.7410500161682542 0.7451981699642986 1.2991391675461639 0.8530588347201378 0.858522435177926 0.7805652830112191 0.9678022036653056 1.0359860365407714 0.9996767159145693 1.0 13.456429477623745 -7.511071340190132 22.017305260539796 1.0110777724480975 0.889036976374645 0.13831807162052823 0.1502126308949491 272.66636822846306 508455.4320494964 0.06936065279303473 0.04381583321277527 3.082681526246604e-08 7.511071340190132 -0.12204079607345253 GPGAPGLAHLQESQAGS(ph)DTDVEEGK ddPTM_PC-9_Lapatinib_30min_R1 1 GPGAPGLAHLQESQAGSDTDVEEGK 25 0 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 GPGAPGLAHLQESQAGS(0.977)DT(0.023)DVEEGK 143.54 1.0804e-06 5072400.0 10154.0 13743.0 12640.0 12298.0 16550.0 11573.0 16648.0 15375.0 10285.0 14881.0 True False 10009.202097984453 13711.1789278674 11600.787991811003 13202.43594492536 15576.561538551912 11078.049767980658 17509.951980710393 16089.378629197028 9126.594994148581 17453.161022313885 0.5734893573254539 0.7855986036190031 0.6646811988372412 0.7564495582230653 0.8924779596450901 0.6347302791636059 1.0032539067463997 0.9218604359764252 0.5229193142995827 1.0 14.091200732787513 -1.7675236003534045 0.09800393713627727 1.0342439289054044 2.2491460438153556e-30 0.21145483198929083 0.14713622002141438 213.5402111751875 1.5713020461765403 2.0469011941992097 29.601552703619603 0.017079549041565573 1.7675236003534045 -1.0342439289054044 GPGAPGLAHLQESQAGS(ph)DTDVEEGKAPQAVPLEK ddPTM_PC-9_Lapatinib_30min_R1 2 GPGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEK 34 1 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 GPGAPGLAHLQES(0.011)QAGS(0.966)DT(0.023)DVEEGKAPQAVPLEK;GPGAPGLAHLQES(0.013)QAGS(0.641)DT(0.347)DVEEGKAPQAVPLEK 101.08 1.6334e-16 18456300.0 133590.0 106394.0 114907.0 87808.0 117580.0 115906.0 107422.0 110849.0 103498.0 94570.0 True False 131684.9821025944 106147.65122982781 105459.7900138471 94265.69323890108 110664.17557117429 110948.97057008262 112983.78554011726 115999.44921416993 91840.96535774347 110916.29849339617 1.1872464542299415 0.9570067940569412 0.9508051697210763 0.8498813476408388 0.9977269082574289 1.0002945651552588 1.0186400652997285 1.045828708583134 0.8280204677332572 1.0 16.759111851008647 -4.760551055375367 24.991399776561313 0.9627433880328858 1.1872467178119326 0.5052715127330125 0.06716631551615102 18.720459532651045 526371.9627478473 0.01684598816898363 0.09891538752643975 1.7355972152038797e-05 4.760551055375367 0.22450332977904675 GPGAPGLAHLQESQAGSDT(ph)DVEEGKAPQAVPLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEK 34 1 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 GPGAPGLAHLQES(0.142)QAGS(0.162)DT(0.696)DVEEGKAPQAVPLEK 47.757 0.005809600000000001 7813400.0 18275.0 16439.0 16957.0 26631.0 30829.0 28700.0 29341.0 25756.0 21359.0 16929.0 True False 21368.59655229712 18070.95527843384 17361.31918978062 25138.951408866913 24788.27875782823 27194.921476537525 26561.60806955565 25079.932290737772 21671.334967741925 19998.093690109738 1.0685316752398843 0.9036338942331797 0.8681487075123985 1.2570673884431114 1.239532084505011 1.3598756910508452 1.3282070021850114 1.2541161512380208 1.0836700389327463 1.0 14.287574861804305 -5.768163616390561 24.99907140098294 1.239547369728072 0.9424576585542377 0.5413600083274464 0.11289957149588528 103.8752297468237 386184.06780381285 0.03150164120466889 0.04794028227999482 1.7054397594546178e-06 5.768163616390561 -0.2970897111738342 GPGASVHDR ddPTM_PC-9_AZD4547_30min_R2 1 GPGASVHDR 9 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;P46379-4;F6U341;A0A0G2JJM1;X6REW1;F6S6P2;F6TC96;F6VEM6;F6X9W3;A0A1B0GX79;A0A0G2JJR8;F6XTU0;F6U1F2;F6UR09;F6WML8 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 0 87.258 0.009256799999999999 588840.0 3147.0 2536.4 6736.5 13462.0 10130.0 9845.4 5221.2 8436.9 6806.8 13245.0 False True 4147.680538333617 3356.2416979946383 6647.1696084490895 10358.54388582668 8723.624356528037 9229.765581609854 5685.876685195357 7133.1709656748435 7166.5935516423815 12781.296581464243 0.32451172006670176 0.2625900804822841 0.5200700544019127 0.8104454677038714 0.6825304694970662 0.7221306166226588 0.44485914624977546 0.558094471887895 0.5607094324088806 1.0 13.64174657551875 -14.522878682393676 0.06517491586219146 2.3782758240723054 3.2166204526709436e-11 0.4781093491266143 0.1529433383655148 384.78651794519976 1.8119073245480972 84.56160801587072 12.05933651809756 3.0000004344056984e-15 14.522878682393676 -2.378275824040139 GPGDLMGPQGLS(ph)PEEMAR ddPTM_PC-9_AZD4547_30min_R2 4 GPGDLMGPQGLSPEEMAR 18 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 GPGDLMGPQGLS(1)PEEMAR;GPGDLMGPQGLS(1)PEEMAR;GPGDLMGPQGLS(1)PEEMAR;GPGDLMGPQGLS(1)PEEMAR 107.63 0.00025641 37752800.0 99128.0 101091.0 137540.0 167073.0 146561.0 135643.0 109363.0 160970.0 119510.0 131349.0 True False 130648.642009512 133766.68880774968 135716.1297329605 128556.90110211872 126213.53497700927 127161.22176715067 119096.09513579613 136095.78522261468 125827.05461549923 126750.51148952385 1.0307543573132667 1.0553542327819776 1.0707343752547906 1.0142515370657432 0.9957635160110658 1.0032403046962124 0.9396103710842983 1.073729672750577 0.9927143735897197 1.0 16.951632043534545 -5.904291342392665 5.411811882866464 1.0018691250372047 1.0522543113031066 0.3456729044660174 0.031617628433418546 0.23772093212719833 10.879761856689134 0.008975316811382498 0.013506795834516533 1.2465469992905537e-06 5.904291342392665 0.05038518626590194 GPGDLMGPQGLS(ph)PEEMAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GPGDLMGPQGLSPEEMAR 18 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 GPGDLMGPQGLS(1)PEEMAR;GPGDLMGPQGLS(1)PEEMAR;GPGDLMGPQGLS(1)PEEMAR;GPGDLMGPQGLS(1)PEEMAR 91.065 0.00076264 47157000.0 184070.0 190090.0 238629.0 215615.0 235845.0 197415.0 213599.0 190868.0 184487.0 148441.0 True False 215229.4154517825 208960.87893895566 244318.82036552194 203534.79058326117 189632.86527749812 187062.2098707546 193365.35639715832 185857.9172413623 187184.77335988576 175352.17824169036 1.2274122717490785 1.191664004600741 1.3933035951727608 1.1607200584798343 1.0814400321627284 1.0667800750836647 1.1027257165328175 1.0599122241024672 1.0674790312663602 1.0 17.419895826435955 -6.025196597501615 4.410665868384436 1.0705836343730788 1.2657698387167933 0.7401779431169714 0.05492757462614274 0.10525584600290122 4.904669919597672 0.016166306740903122 0.022519362129620205 9.436336131849995e-07 6.025196597501615 0.19518620434371448 GPGDLMGPQGLS(ph)PEEMAR ddPTM_PC-9_Lapatinib_30min_R1 7 GPGDLMGPQGLSPEEMAR 18 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 GPGDLMGPQGLS(1)PEEMAR;GPGDLMGPQGLS(1)PEEMAR;GPGDLMGPQGLS(1)PEEMAR;GPGDLMGPQGLS(1)PEEMAR;GPGDLMGPQGLS(1)PEEMAR;GPGDLMGPQGLS(1)PEEMAR;GPGDLMGPQGLS(1)PEEMAR 169.72 1.0261e-24 30746400.0 139679.1 152454.8 169691.80000000002 150338.8 161612.40000000002 153786.8 135310.9 143694.8 173208.0 128906.8 True False 137687.25041999016 152101.80027739488 155740.395233291 161395.21686753517 152106.6763742036 147209.69705854025 142316.63632068134 150371.3849916576 153699.49107890006 151188.16862248624 0.910701225330617 1.0060430102648439 1.0301096749321144 1.0675122156584602 1.0060752621060638 0.9736852982598119 0.9413212529615533 0.994597569120186 1.0166105752804278 1.0 17.205985718906334 -5.3848107538467325 0.006278572615216903 1.0427173512344214 0.9485066810271328 0.0017220843475912462 0.04199757407973587 749970.2955251384 905.3634898320332 6544.157117049359 7045.842137446832 4.122771319356133e-06 5.3848107538467325 -0.09421067020728868 GPGEGVLT(ph)LR ddPTM_PC-9_AZD4547_30min_R2 1 GPGEGVLTLR 10 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 GPGEGVLT(1)LR 86.463 0.027507 4295300.0 16818.0 12220.0 17643.0 16020.0 13047.0 14284.0 18227.0 12653.0 11442.0 12665.0 True False 22165.774163868697 16169.87602487561 17409.042292268587 12326.836506532723 11235.649257613162 13390.819221942756 19849.167689622256 10697.769587014633 12046.800760694041 12221.602204925974 1.813655345036077 1.3230569735249824 1.424448447949958 1.0086105160225503 0.9193270300586761 1.0956680635985292 1.624105199694845 0.8753164607749094 0.9856973380984796 1.0 13.577145808861628 -3.7449394885463336 0.7916211471535444 1.089156251678623 4.722325291556989 0.5168692795166139 0.21300506331444483 9.820368508737392 1.3724017712750747 0.0812894357692617 46.08657229035998 0.00017991215742604757 3.7449394885463336 3.633169039878366 GPGEPDS(ph)PTPLHPPTPPILSTDR ddPTM_PC-9_AZD4547_30min_R2 1 GPGEPDSPTPLHPPTPPILSTDR 23 0 Q03164-2;Q03164;Q03164-3 Q03164-2 KMT2A Histone-lysine N-methyltransferase 2A;MLL cleavage product N320;MLL cleavage product C180 1 GPGEPDS(0.407)PT(0.407)PLHPPT(0.18)PPILS(0.003)T(0.003)DR 57.673 0.0042591 3627200.0 2118.6 2647.2 7486.6 7626.9 7579.9 5992.4 5244.6 5505.4 6449.0 4071.8 True False 2792.2707303824573 3502.8556311825464 7387.322792342462 5868.63603943036 6527.5617235979125 5617.694280703567 5711.359239863551 4654.666931506388 6789.88097410556 3929.2475213594607 0.7106375241579013 0.8914825579556798 1.8800858821402422 1.493577588973041 1.6612752666035846 1.4297124958826541 1.4535503830737306 1.1846204409886458 1.7280359501903721 1.0 11.940037337312328 -5.108847005846134 6.029051220032274 1.4884770520094142 0.753952058469128 0.5628977958317514 0.24083087893375837 0.14129796042488119 6.543072188476343 0.05849508443027549 0.16169478712983815 7.783106876410767e-06 5.108847005846134 -0.7345249935402861 GPGGSQGSQGPS(ph)PQGAR ddPTM_PC-9_AZD4547_30min_R2 3 GPGGSQGSQGPSPQGAR 17 0 Q96MG7 Q96MG7 NDNL2 Melanoma-associated antigen G1 1 GPGGSQGS(0.001)QGPS(0.999)PQGAR;GPGGS(0.006)QGSQGPS(0.994)PQGAR;GPGGSQGSQGPS(1)PQGAR 186.17 2.8928e-08 48586700.0 7892.400000000001 9406.93 13468.4 17971.0 15711.7 14161.4 10872.8 16256.2 11120.54 13618.1 True False 10402.019027881872 12447.5361599577 13289.800215903773 13828.063599182242 13530.401658683268 13275.88541932373 11840.458136595435 13744.177820313545 11708.349041367634 13141.334464027046 0.7915496752903026 0.9472048819723338 1.0112976161046001 1.052257184156985 1.0296063687992456 1.0102387589072481 0.9010088107115288 1.0458738309976598 0.8909558670329827 1.0 13.681824164104691 -4.7805104553032605 2.8818099794425116 0.9947424644447417 0.7554818556698067 0.5707905317145718 0.05226057769377673 0.2945736435583032 3.425156746604668 0.013301005083799495 0.167793585019964 1.6576374300313473e-05 4.7805104553032605 -0.23926060877493494 GPGGSQGSQGPS(ph)PQGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 GPGGSQGSQGPSPQGAR 17 0 Q96MG7 Q96MG7 NDNL2 Melanoma-associated antigen G1 1 GPGGSQGS(0.001)QGPS(0.999)PQGAR;GPGGSQGSQGPS(1)PQGAR;GPGGSQGSQGPS(1)PQGAR;GPGGSQGSQGPS(1)PQGAR;GPGGSQGSQGPS(1)PQGAR;GPGGSQGS(0.015)QGPS(0.985)PQGAR 171.25 1.1900000000000001e-05 57154100.0 26552.2 34705.7 33029.2 34557.8 40104.200000000004 32222.8 36658.9 29240.5 28744.4 25011.800000000003 True False 31046.96303014518 38151.052534019174 33816.74139193853 32621.63850389925 32246.06990040855 30532.979643002567 33186.30360454766 28472.9678578707 29164.732470937848 29546.24134670016 1.0507923043691183 1.2912320076976571 1.1445361525050737 1.1040875934475693 1.0913763792161644 1.0333964068296833 1.1231988263797905 0.9636747877256026 0.9870877357534034 1.0 14.850686992680775 -6.739049913960765 0.6113518368693326 0.9850729417689541 1.181201251772444 0.47787801145145703 0.06580543009553562 0.6871353571359765 0.5618543969891644 0.05195994272770771 0.05935459443981306 1.823686091949309e-07 6.739049913960765 0.19612831000348985 GPGGSQGSQGPS(ph)PQGAR ddPTM_PC-9_Lapatinib_30min_R1 5 GPGGSQGSQGPSPQGAR 17 0 Q96MG7 Q96MG7 NDNL2 Melanoma-associated antigen G1 1 GPGGSQGSQGPS(1)PQGAR;GPGGSQGSQGPS(1)PQGAR;GPGGSQGS(0.001)QGPS(0.999)PQGAR;GPGGSQGSQGPS(1)PQGAR;GPGGSQGSQGPS(1)PQGAR 209.19 1.4767e-17 47261000.0 24676.8 26006.0 26342.9 22792.5 24585.7 26471.6 23983.3 24023.399999999998 30107.800000000003 18799.9 True False 24324.9043068291 25945.784704803864 24177.088448534654 24468.736483551096 23139.61746334597 25339.47137631356 25225.037922811847 25139.614865733438 26716.742514810583 22049.437665707872 1.1031983978738886 1.1767095877077962 1.096494559865161 1.1097215654440844 1.0494425215811098 1.149211683331157 1.1440218251934284 1.140147664846416 1.2116745524245947 1.0 14.428454242260154 GPGLLES(ph)PSIFNFTADR ddPTM_PC-9_AZD4547_30min_R2 2 GPGLLESPSIFNFTADR 17 0 Q92615 Q92615 LARP4B La-related protein 4B 1 GPGLLES(0.671)PS(0.328)IFNFT(0.002)ADR;GPGLLES(0.705)PS(0.295)IFNFTADR 221.13 5.9698e-23 39007000.0 91369.0 100566.0 139605.0 167810.0 150304.0 137726.0 105536.0 154138.0 117457.0 122065.0 True False 120422.4414067377 133071.99282468422 137753.7464837133 129123.99713865516 129436.88403589214 129113.97144786395 114928.49954967776 130319.51383887294 123665.53722678196 117791.54150369423 1.0223352192310087 1.129724521183134 1.169470614996519 1.0962077199287312 1.098863996374754 1.0961226060855536 0.9756939936648449 1.1063571473405482 1.0498677209594334 1.0 16.84587641879358 -7.029828390057399 23.616015808060162 1.0409949978514346 1.1070097993813441 0.33650786169668245 0.04697433599606447 440.12434261744147 348457.9651540062 0.017937844646028708 0.0139229258548063 9.336231458326067e-08 7.029828390057399 0.06601480152990957 GPGLLES(ph)PSIFNFTADR ddPTM_PC-9_Lapatinib_30min_R1 2 GPGLLESPSIFNFTADR 17 0 Q92615 Q92615 LARP4B La-related protein 4B 1 GPGLLES(0.67)PS(0.33)IFNFTADR;GPGLLES(0.661)PS(0.339)IFNFT(0.001)ADR 176.94 4.4203e-06 1383270.0 6216.299999999999 5955.5 9030.1 8849.6 7067.1 6270.14 5192.21 3554.8999999999996 8266.2 4687.4 True False 6127.654422070192 5941.710405654831 8287.680035194026 9500.429105400184 6651.42707245318 6001.980728610232 5461.037228121352 3720.0736318004892 7335.1735090550355 5497.6108444321035 1.1146031604394455 1.0807804651492394 1.507505763815142 1.7281014197325506 1.2098759371427033 1.091743467926426 0.9933473617275416 0.6766709643641152 1.3342474970712028 1.0 12.424589072073458 -6.750729138393491 2.8553445273061255 0.985086582392879 1.3570918418153461 0.3244354233061737 0.2287338907988352 0.3159955882276217 5.291712252276451 0.08934162668128498 0.08350673450730348 1.7752963558850446e-07 6.750729138393491 0.3720052594224671 GPGPGQGS(ph)PGGGPGPR ddPTM_PC-9_AZD4547_30min_R2 2 GPGPGQGSPGGGPGPR 16 0 H0YDS2;Q8IYL2 H0YDS2 TRMT44 Probable tRNA (uracil-O(2)-)-methyltransferase 1 GPGPGQGS(1)PGGGPGPR;GPGPGQGS(1)PGGGPGPR 115.58 0.00017381 8734400.0 36915.0 31168.0 45267.0 62922.0 49314.0 45962.0 39845.0 47411.0 42511.0 49554.0 True False 48653.20212030042 41242.446476540325 44666.73000306763 48416.30503520923 42467.60232160155 43087.988874190196 43391.127810007085 40084.71934639616 44758.044672073425 47819.12954306368 1.0174422367200475 0.8624675285943735 0.9340766013493167 1.0124882133541926 0.8880881506501955 0.9010617567889261 0.9074010385515499 0.8382569847972186 0.9359861858582434 1.0 15.545300248299638 GPGPGQGS(ph)PGGGPGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GPGPGQGSPGGGPGPR 16 0 H0YDS2;Q8IYL2 H0YDS2 TRMT44 Probable tRNA (uracil-O(2)-)-methyltransferase 1 GPGPGQGS(1)PGGGPGPR;GPGPGQGS(1)PGGGPGPR 108.25 0.00081566 6517500.0 29872.8 25884.9 34192.4 35260.6 40524.5 31800.8 38322.9 30617.8 33369.6 26117.7 True False 34929.675025305696 28454.581804655532 35007.67649139911 33285.0628984076 32584.015132557328 30133.110065891095 34692.67747823093 29814.11519224067 33857.56727091911 30852.632262400555 1.1321457024551433 0.9222740401094569 1.1346738973083412 1.078840295224061 1.0561178331700005 0.9766787420149454 1.1244641035218947 0.9663394338179209 1.0973963901349386 1.0 14.913105960979527 -6.545000253569397 24.930253432047003 1.0343464589327767 1.0622317772778316 0.04703478138038364 0.07157269921001415 964.1136664879753 1086518.7792031774 0.022422871028257046 0.02242491734026478 2.851016602894288e-07 6.545000253569397 0.02788531834505492 GPGPGQGS(ph)PGGGPGPR ddPTM_PC-9_Lapatinib_30min_R1 2 GPGPGQGSPGGGPGPR 16 0 H0YDS2;Q8IYL2 H0YDS2 TRMT44 Probable tRNA (uracil-O(2)-)-methyltransferase 1 GPGPGQGS(1)PGGGPGPR;GPGPGQGS(1)PGGGPGPR 114.58 0.00019077 6802100.0 41037.0 44960.0 46229.0 40958.0 46175.0 40443.0 40147.0 36632.0 49390.0 32957.0 True False 40451.8048547359 44855.89788233416 42428.23006910053 43970.18795188268 43459.07728354285 38713.34716723768 42225.61521922033 38334.05645169075 43827.17810024294 38653.5735375579 1.046521735317195 1.1604592739336181 1.097653494517783 1.137545223578329 1.1243223667616569 1.0015463933657183 1.092411680337696 0.9917338280364506 1.1338454401287914 1.0 15.238314177569967 -6.741021176821643 24.990114750586578 1.0464223414237348 1.116398035860252 0.32708555740554723 0.049601399166522696 269.8193505139568 330235.1040918359 0.015078057371556049 0.015060533949718366 1.8154271377845959e-07 6.741021176821643 0.0699756944365173 GPGQPS(ph)SPQR ddPTM_PC-9_Lapatinib_30min_R1 2 GPGQPSSPQR 10 0 O95400 O95400 CD2BP2 CD2 antigen cytoplasmic tail-binding protein 2 1 GPGQPS(0.746)S(0.254)PQR;GPGQPS(0.861)S(0.139)PQR 70.72800000000001 0.035018 57929000.0 31158.0 62733.0 63912.0 55926.0 73027.0 65116.0 63914.0 76372.0 59035.0 56044.0 True False 30713.68120632258 62587.745592804065 58657.40206745446 60038.984603666904 68731.69543660598 62331.14047280985 67223.15418639618 79920.52192969318 52385.8566338903 65731.13072606406 0.46726232862663697 0.95217813692632 0.8923838890268064 0.9134025832277357 1.0456490657835606 0.9482742771089129 1.0226988862636512 1.2158701827717482 0.7969717857465363 1.0 16.004289182472682 -4.545213891494845 2.0550018349736883 0.9894560263510431 6.577983064191466e-16 0.6731956131213392 0.10583167785605137 1.0174007941655032 2.6113203055425163 0.027648173992416675 2.3720442768354837 2.8496144771203454e-05 4.545213891494845 -0.9894560263510425 GPGQPSS(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 1 GPGQPSSPQR 10 0 O95400 O95400 CD2BP2 CD2 antigen cytoplasmic tail-binding protein 2 1 GPGQPS(0.129)S(0.871)PQR 72.152 0.031307 29986000.0 39886.0 48677.0 46894.0 48330.0 45918.0 52863.0 46946.0 62995.0 48123.0 37420.0 True False 52568.91831966145 64410.888319383776 46272.1549200047 37188.26519105661 39543.078302374575 49557.46825325953 51124.10305354733 53260.5702310904 50666.68353494832 36109.937189761535 1.4558019872315542 1.7837441250838448 1.2814244089331874 1.0298623615884002 1.09507469078585 1.3724052742830817 1.4157904176040177 1.4749560474503314 1.4031230037507278 1.0 15.140108290389911 -5.281897906843913 23.257184153549996 1.2716426996745476 1.6197729469450306 0.40272355946795735 0.17517063630210727 308.97962313263827 351247.12138802285 0.04908022996686504 0.10242838955204839 5.2251900737949974e-06 5.281897906843913 0.34813024727048303 GPGQPSS(ph)PQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GPGQPSSPQR 10 0 O95400 O95400 CD2BP2 CD2 antigen cytoplasmic tail-binding protein 2 1 GPGQPS(0.035)S(0.965)PQR;GPGQPS(0.243)S(0.757)PQR;GPGQPS(0.013)S(0.987)PQR;GPGQPS(0.126)S(0.874)PQR 87.713 0.010451 67557300.0 83939.0 128749.0 118685.0 87536.0 110839.0 84148.0 98231.0 80764.0 78871.0 69476.0 True False 98148.21482918 141530.34984750193 121514.90051536885 82631.64171554087 89120.8936144192 79735.13074591226 88925.84854914686 78644.03057653128 80024.3391657276 82071.44882828648 1.1958874399126307 1.7244772922629648 1.4805989445806873 1.0068256731817475 1.0858939970815171 0.9715331200346863 1.0835174694576364 0.9582386042809334 0.9750569815473595 1.0 16.32459280133633 -5.75721166225842 9.065337993934394 1.0140368699824958 1.4935044225055245 0.731920452770632 0.1259933210568007 0.05245317414238288 47.7266713065339 0.03301949180261115 0.05361783689899438 1.7489940729990173e-06 5.75721166225842 0.47946755252302875 GPGQVPTATSALSLELQEVEPLGLPQAS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 2 GPGQVPTATSALSLELQEVEPLGLPQASPSR 31 0 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 GPGQVPTATSALSLELQEVEPLGLPQAS(0.854)PS(0.146)R;GPGQVPTATSALSLELQEVEPLGLPQAS(0.597)PS(0.403)R 136.47 1.2093e-17 3102300.0 24590.0 19867.0 26097.0 20546.9 21754.3 23911.1 22991.0 19155.2 25023.0 19346.3 True False 24239.34209074629 19820.99918212485 23951.405397333187 22057.9875684491 20474.754844599396 22888.477992496515 24181.36148417302 20045.220521495594 22204.646236128345 22690.28217767565 1.0682697509418688 0.8735457332313915 1.0555798826027083 0.9721336824163145 0.9023578765690252 1.0087348325273744 1.0657144452775649 0.8834275556615836 0.9785971836866308 1.0 14.46978693011113 -4.4470486925275505 18.439621672266366 0.9720596900680759 3.475541692500409 0.1738232004439071 0.0635092944667159 107.02934163704317 27968.479196980898 0.014874654825630175 816.207059308376 3.572327834355125e-05 4.4470486925275505 2.503482002432333 GPGYTS(ph)GTNSEAS(ph)NAS(ph)ETESDHR ddPTM_PC-9_AZD4547_30min_R2 1 GPGYTSGTNSEASNASETESDHR 23 0 G3V0J0;Q06787-2;Q06787-7;A0A087WXC0;R9WNI0;Q06787-9;Q06787 G3V0J0 FMR1 Fragile X mental retardation protein 1 3 GPGY(0.132)T(0.154)S(0.5)GT(0.181)NS(0.039)EAS(0.97)NAS(0.678)ET(0.3)ES(0.047)DHR 50.172 0.010287000000000001 94658000.0 13468.0 9813.8 13712.0 17521.0 20300.0 17110.0 15699.0 17094.0 17357.0 15192.0 True False 17750.54384819737 12985.918930681191 13530.169920738363 13481.804146751549 17481.69540350634 16040.10899520025 17096.180587007195 14452.515081042293 18274.4555849822 14660.132704084917 1.2108037632736663 0.885798184286748 0.9229227452332883 0.9196236090683519 1.1924650176348826 1.0941312277978776 1.1661682013453736 0.9858379438144668 1.2465409388750064 1.0 13.839610542411263 -6.255571250467568 24.990163368575324 1.1150783684028058 0.9732975587275373 0.23974871884190163 0.11213832356911943 647.1592022065204 2756007.680006852 0.03214233524850735 0.04041521674314173 5.551735277318949e-07 6.255571250467568 -0.14178080967526852 GPHHLDNSS(ph)PGPGSEAR ddPTM_PC-9_AZD4547_30min_R2 5 GPHHLDNSSPGPGSEAR 17 0 H3BUF6;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 GPHHLDNS(0.226)S(0.774)PGPGSEAR;GPHHLDNS(0.178)S(0.822)PGPGSEAR;GPHHLDNS(0.243)S(0.757)PGPGSEAR;GPHHLDNS(0.36)S(0.64)PGPGSEAR;GPHHLDNS(0.019)S(0.981)PGPGSEAR 180.03 1.6323e-08 65696100.0 113389.9 111762.5 160269.9 174974.2 157586.1 150796.4 116824.3 184417.1 155813.5 152300.0 True False 149445.5295435639 147887.5424901933 158144.61640750748 134636.60151444175 135707.99014908844 141367.07726965589 127221.43638134275 155919.67467837146 164049.48351043536 146968.02335651184 1.016857450556045 1.0062565931872876 1.0760477877822694 0.9160945247786534 0.9233844686057384 0.9618900359483689 0.8656402493264249 1.0609088366123351 1.1162256915743343 1.0 17.16514276852378 -7.955967893624578 24.994654633240426 1.0682646086867882 0.9681690488207847 0.31993099962427896 0.0613908474444056 147.62511303152235 83798.65942733905 0.035210014266697294 0.016914325110263858 1.1067055971101953e-08 7.955967893624578 -0.10009555986600349 GPHHLDNSS(ph)PGPGSEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GPHHLDNSSPGPGSEAR 17 0 H3BUF6;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 GPHHLDNS(0.206)S(0.78)PGPGS(0.014)EAR;GPHHLDNS(0.334)S(0.666)PGPGSEAR;GPHHLDNS(0.196)S(0.804)PGPGSEAR 199.97 9.083200000000001e-13 28386100.0 30132.0 30648.2 41063.7 34606.8 40281.9 32003.5 32931.6 31281.1 29227.5 21674.2 True False 35232.752465872305 33690.750749102524 42042.814342949474 32667.893192759384 32388.950861038677 30325.18012105812 29812.080443862797 30460.004270065114 29654.896894502428 25603.560887127205 1.3760879832768262 1.3158619184896796 1.642069028143952 1.2759121021007644 1.2650174326854273 1.1844126000577062 1.164372431447671 1.1896784359155137 1.1582333029860752 1.0 14.644056850592795 -6.3329086786928315 1.6808822541683606 1.1510885393500243 1.4280989084671167 0.6179926744369386 0.0997621604562633 0.25790486809575347 1.4459771716273588 0.03624136223635046 0.04590708095896802 4.646129614798006e-07 6.3329086786928315 0.2770103691170924 GPHHLDNSS(ph)PGPGSEAR ddPTM_PC-9_Lapatinib_30min_R1 3 GPHHLDNSSPGPGSEAR 17 0 H3BUF6;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 GPHHLDNS(0.22)S(0.656)PGPGS(0.124)EAR;GPHHLDNS(0.118)S(0.881)PGPGS(0.001)EAR;GPHHLDNS(0.252)S(0.748)PGPGSEAR 157.57 1.5887e-05 22834300.0 39241.1 47580.6 69434.2 49926.6 67901.1 64667.0 74289.8 71222.7 74694.1 64878.0 True False 38681.51471806361 47470.430044043365 63725.58809976291 53598.3687142552 63907.29079669895 61901.343156139694 78136.16234121688 74531.9666532495 66281.26389425703 76092.07585549905 0.5083514187669276 0.6238551059402168 0.8374799528505381 0.7043883099738267 0.8398678847723995 0.813505775209656 1.0268633292328575 0.9794970871183455 0.8710665749233466 1.0 16.215458600437028 -4.295449856756501 0.3475426414025644 0.9902590060389801 5.308009652772204e-16 0.8107009954078864 0.0691967664333598 4.017559461335474 0.30007659357984073 0.06712004069479363 1.7829983224238126 5.064658222285994e-05 4.295449856756501 -0.9902590060389795 GPHHLDNSSPGPGSEAR ddPTM_PC-9_AZD4547_30min_R2 2 GPHHLDNSSPGPGSEAR 17 0 H3BUF6;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 0 ; 94.53200000000001 0.00073154 1389620.0 4245.139999999999 2236.74 8087.599999999999 12538.5 10045.4 8522.599999999999 6669.5 11728.599999999999 7781.9 8510.0 False True 5595.006215602654 2959.722463165325 7980.353139656039 9647.94254289392 8650.769606225733 7989.680474722017 7263.072579466487 9916.214366415852 8193.235346936275 8212.067490242405 0.6813151769941798 0.36041136616108826 0.9717836767827724 1.1748493974699579 1.0534216403487422 0.972919485161973 0.8844389781375377 1.2075173978049154 0.9977067719756924 1.0 13.00352976883509 -5.349111837930831 5.754955932606194 1.0424839713050504 0.5237471898984234 0.76111016567906 0.11500197284693624 0.09076564995364063 4.658060595860361 0.029510356578703333 0.06299573971830846 4.4759802552307284e-06 5.349111837930831 -0.518736781406627 GPIAQWADGAIS(ph)PNGHRPQLR ddPTM_PC-9_AZD4547_30min_R2 1 GPIAQWADGAISPNGHRPQLR 21 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;Q5SRD0;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21D;FAM21A WASH complex subunit FAM21C;Putative WASH complex subunit FAM21;WASH complex subunit FAM21A 1 GPIAQWADGAIS(1)PNGHRPQLR 47.222 0.026331999999999998 8962700.0 39160.0 34718.0 40346.0 52315.0 45154.0 43697.0 38106.0 46915.0 39190.0 41701.0 True False 51612.06542139954 45939.914552506634 39810.98567839191 40254.58500869287 38885.14651477462 40964.619682248114 41497.360178896495 39665.36474945003 41261.50339202931 40241.06068279656 1.2825721923245474 1.1416178841465376 0.9893125330916411 1.000336082739044 0.9663052080383754 1.0179806145060406 1.0312193434960082 0.985693818115668 1.0253582458294646 1.0 15.296380712069707 -4.957825272084719 2.2872633185914593 1.0012490969210526 1.303928297727557 0.9521132726611639 0.020044567486492852 0.0809237195222089 0.6683947376145558 0.0055981777870642456 0.04293172697574177 1.1019825764907691e-05 4.957825272084719 0.30267920080650446 GPIAQWADGAIS(ph)PNGHRPQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GPIAQWADGAISPNGHRPQLR 21 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;Q5SRD0;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21D;FAM21A WASH complex subunit FAM21C;Putative WASH complex subunit FAM21;WASH complex subunit FAM21A 1 GPIAQWADGAIS(1)PNGHRPQLR;GPIAQWADGAIS(1)PNGHRPQLR 61.015 0.003867 11903000.0 41832.0 41912.0 48631.0 46162.0 55313.0 58010.0 62083.0 46716.0 51559.0 41279.0 True False 48913.331380338874 46072.74637324165 49790.54747409456 43575.692799223245 44474.81471769284 54967.8534792314 56202.04879800354 45489.75449969345 52312.952834955126 48762.55593561577 1.0030920332585147 0.944838626467291 1.021081576196213 0.8936302038137406 0.912068981298185 1.127255379143966 1.152565687332112 0.9328828980941114 1.0728099015980042 1.0 15.573486127718317 -6.752655810000407 24.998532454650395 1.0588743902690128 0.9546491470407259 0.3649171813148041 0.06736534841309685 220.75116570249844 628269.1866707407 0.023179656317486603 0.022847097798053686 1.7674380076917005e-07 6.752655810000407 -0.10422524322828686 GPIHS(ph)PVELK ddPTM_PC-9_AZD4547_30min_R2 3 GPIHSPVELK 10 0 Q16649 Q16649 NFIL3 Nuclear factor interleukin-3-regulated protein 1 GPIHS(1)PVELK;GPIHS(1)PVELK;GPIHS(1)PVELK 74.46 0.014648 10910100.0 73555.0 72034.0 83445.0 114320.0 101327.0 97690.0 77363.0 90305.0 82325.0 89495.0 True False 96943.95996095639 95317.58179835434 82338.46477800551 87965.29022639338 87259.4950813343 91581.42885687402 84248.1571280104 76350.43725245846 86676.53143018152 86361.80729015781 1.1225327839104238 1.1037006379232774 0.9534129421512139 1.018567037751401 1.0103944998297736 1.0604390034263567 0.9755256376809486 0.8840764181316492 1.00364425143358 1.0 16.39810581444838 -5.210696053090912 7.109970110414468 0.9881580360802228 1.1146473233492307 0.5627703937425796 0.04403264127786684 0.20076604336534 23.764321738750265 0.012135848901869604 0.03234829765926558 6.156075633188945e-06 5.210696053090912 0.12648928726900788 GPIHS(ph)PVELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GPIHSPVELK 10 0 Q16649 Q16649 NFIL3 Nuclear factor interleukin-3-regulated protein 1 GPIHS(1)PVELK;GPIHS(1)PVELK 75.08800000000001 0.014161000000000002 5140900.0 42378.0 46977.0 43281.0 54534.0 55008.0 62076.0 59936.0 61878.0 55127.0 51066.0 True False 49551.758396347315 51640.5660998228 44312.98318410657 51478.6367816135 44229.57727823205 58820.62528144747 54258.42818093746 60253.768065160366 55933.12808496231 60323.86156176642 0.8214288195991996 0.8560553778034804 0.7345846574946782 0.8533710450366946 0.7332020221043838 0.9750805694231003 0.8994521699407708 0.998838046922207 0.9272139852600719 1.0 15.880441163555469 -6.7731881085838115 24.999993370948783 0.9562528141697365 0.8022187122447295 0.7331192377700623 0.04834567033821679 114.4322345368288 243497.63667432894 0.01602265846027318 0.0142425813008452 1.6858226767037854e-07 6.7731881085838115 -0.154034101925007 GPIHS(ph)PVELK ddPTM_PC-9_Lapatinib_30min_R1 4 GPIHSPVELK 10 0 Q16649 Q16649 NFIL3 Nuclear factor interleukin-3-regulated protein 1 GPIHS(1)PVELK;GPIHS(1)PVELK;GPIHS(1)PVELK;GPIHS(1)PVELK 74.46 0.014648 11140500.0 162095.0 130133.0 139797.0 133188.0 145519.0 146589.0 137385.0 136030.0 152687.0 132339.0 True False 159783.4955754178 129831.68503384783 128303.43029202559 142983.08982214352 136959.85852136172 140319.7301856491 144498.12307003228 142350.45040193002 135489.78219461004 155213.6198193668 1.0294424919756995 0.8364709565110474 0.8266248183718765 0.921201953723798 0.8823958791809101 0.9040426371664368 0.9309629093000671 0.9171260264891279 0.8729245690699643 1.0 17.243895632372507 -7.064653769888907 4.556552917677832 0.9231001806756827 0.8928800985084776 0.04800279381326367 0.0597233422578345 0.7817796183607341 31.967624178948974 0.022911763138479223 0.017938033916645665 8.616804310017223e-08 7.064653769888907 -0.030220082167205065 GPKPEPPGS(ph)GSPAPPR ddPTM_PC-9_AZD4547_30min_R2 2 GPKPEPPGSGSPAPPR 16 1 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 GPKPEPPGS(0.597)GS(0.403)PAPPR;GPKPEPPGS(0.523)GS(0.477)PAPPR 66.325 0.012699 105997100.0 76052.0 72279.0 108062.0 108316.0 108344.0 108168.0 88653.0 116370.0 87816.0 90420.0 True False 100234.95402012985 95641.77325711821 106629.0272735436 83345.41966551803 93302.3057535708 101404.23786048043 96542.94525638224 98387.69041657282 92457.77448008269 87254.42332170586 1.1487664487858105 1.0961252119504394 1.2220472408648424 0.9551999370647904 1.069313190112626 1.162167303388212 1.1064533072487308 1.1275954464087024 1.0596342392773848 1.0 16.412940649468105 -14.52287874520765 0.2243223094141178 0.4496828962410638 1.1178667465941179 0.1977001389161167 0.06655872900378174 279.3713425663489 2.789379012292607 69.53821592865907 0.123755411794355 3.0000000005021035e-15 14.52287874520765 0.6681838503530542 GPKPEPPGS(ph)GSPAPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GPKPEPPGSGSPAPPR 16 1 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 GPKPEPPGS(0.753)GS(0.247)PAPPR;GPKPEPPGS(0.597)GS(0.403)PAPPR;GPKPEPPGS(0.762)GS(0.238)PAPPR;GPKPEPPGS(0.816)GS(0.184)PAPPR 86.189 0.0021448 56590000.0 418446.0 427710.0 448646.0 527707.0 572250.0 524178.0 536510.0 479849.0 432475.0 391313.0 True False 489280.6431147756 470170.22216308396 459343.4221394301 498141.2876391772 460121.7204309975 496689.1829173689 485687.88880397036 467253.4721920405 438799.1287126819 462254.9492679962 1.0584649096555396 1.0171231760906443 0.9937014689984897 1.077633216102951 0.9953851682056044 1.0744918658067395 1.050692674190036 1.0108133464702969 0.9492578271093521 1.0 18.818329240785957 -8.024151907057167 5.237383116856055 0.9752865051944382 1.0367228275624278 0.41598035923534393 0.03002019326345418 0.17725462033633702 13.868035947667922 0.019214519567166317 0.007586278606700519 9.459062454254461e-09 8.024151907057167 0.06143632236798968 GPKPEPPGS(ph)GSPAPPR ddPTM_PC-9_Lapatinib_30min_R1 3 GPKPEPPGSGSPAPPR 16 1 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 GPKPEPPGS(0.779)GS(0.221)PAPPR;GPKPEPPGS(0.5)GS(0.5)PAPPR;GPKPEPPGS(0.73)GS(0.27)PAPPR 80.016 0.0039756999999999995 102458400.0 124525.0 127690.0 136656.0 123591.0 137075.0 130721.0 106310.0 124751.0 127616.0 109812.0 True False 122749.25066491155 127394.34165025003 125420.67118741476 132680.2944274897 129012.5179998189 125130.36755553428 111814.21162117488 130547.38688591593 113242.54222394434 128792.85788470777 0.9530749816483899 0.9891413525763233 0.973816974382914 1.030183634454807 1.0017055302500373 0.9715629392085385 0.8681709021572317 1.01362287497944 0.8792610404321978 1.0 16.97469306649178 -7.009956503272512 24.51822354699357 0.9383229413170759 0.9905089006378751 0.20251230840650047 0.046113982924071435 552.1359095461079 1359653.8224631988 0.015855246399837174 0.013185656247414022 9.773351009693881e-08 7.009956503272512 0.05218595932079917 GPKPEPPGSGS(ph)PAPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GPKPEPPGSGSPAPPR 16 1 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 GPKPEPPGS(0.172)GS(0.828)PAPPR;GPKPEPPGS(0.4)GS(0.6)PAPPR 140.75 0.00010552 72755700.0 83583.0 51351.0 70853.0 123224.0 118283.0 107226.0 97713.0 122955.0 68496.0 70812.5 True False 97731.95106050085 56448.78791306382 72542.40423149872 116320.15877759823 95106.2952516203 101602.87979941505 88456.91725914231 119727.56153159124 69497.62441829909 83650.24569855828 1.1683402749668823 0.6748191525519538 0.8672108925168284 1.3905537013814535 1.1369517741088888 1.21461543777828 1.0574615354736117 1.4312876254188307 0.8308119580274812 1.0 16.352082157321398 -5.7289937001331985 24.831002260942213 1.1677234662415863 0.8805926173361242 0.23892488410652846 0.20034568596892158 213.57915499082432 163452.6052078 0.05074501616795531 0.08788404630710839 1.8664067646963555e-06 5.7289937001331985 -0.28713084890546214 GPLQS(ph)VQVFGR ddPTM_PC-9_AZD4547_30min_R2 1 GPLQSVQVFGR 11 0 M0R210;P62249;M0R3H0;Q6IPX4 M0R210 RPS16 40S ribosomal protein S16 1 GPLQS(1)VQVFGR 83.87700000000001 0.012345 3281100.0 5465.1 13022.0 10618.0 10413.0 9672.9 11207.0 5516.2 10136.0 8417.7 9786.4 True False 7202.888118858296 17231.106840910812 10477.19838232205 8012.443729246266 8329.984801407702 10506.224518364068 6007.131113704633 8569.714102108615 8862.64243692485 9443.781114748333 0.7627123110265189 1.8245982865910593 1.1094283375500764 0.848435984685546 0.8820603421651505 1.112501909003007 0.636093852739059 0.9074452274974174 0.9384633473857288 1.0 13.205148888244032 -5.520222032061866 15.562183892122434 0.9027195098476753 1.3369933666185203 0.2607089686509175 0.2639682083693088 0.8697401813679309 5072.160874354547 0.0662617940873728 0.11985796595351435 3.018408171584603e-06 5.520222032061866 0.43427385677084496 GPLQS(ph)VQVFGR ddPTM_PC-9_Lapatinib_30min_R1 2 GPLQSVQVFGR 11 0 M0R210;P62249;M0R3H0;Q6IPX4 M0R210 RPS16 40S ribosomal protein S16 1 GPLQS(1)VQVFGR;GPLQS(1)VQVFGR 99.669 0.0044663 7046100.0 13074.8 16703.7 19303.2 13268.1 17102.8 18417.8 17334.3 17897.4 15498.8 13406.8 True False 12888.350954375335 16665.023608922278 17716.16540850681 14243.880335084099 16096.846929398525 17630.113627988765 18231.7852366187 18728.978541670956 13753.161934400592 15724.14751656191 0.819653398748664 1.059836381677885 1.1266852711631425 0.9058602585660891 1.0237023604900717 1.121212683194389 1.159476863048731 1.1910965934365676 0.8746523091261182 1.0 13.940694183174413 -6.57561832681785 6.458371648379329 1.086033390275893 0.9908891574087815 0.11267869746195114 0.1138084604632798 0.4272984376048721 38.82018859123411 0.037777494648123196 0.03791697473646532 2.6569395476443865e-07 6.57561832681785 -0.09514423286711149 GPLS(ph)PFNSR ddPTM_PC-9_AZD4547_30min_R2 3 GPLSPFNSR 9 0 A1L390-3;A1L390;A0A0U1RR71;G3V3I3;G3V278 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 GPLS(0.918)PFNS(0.082)R;GPLS(0.999)PFNS(0.001)R;GPLS(0.999)PFNS(0.001)R 91.31299999999999 0.0078972 55306100.0 70686.0 80610.0 139061.0 184284.0 160670.0 149830.0 148657.0 177843.0 121361.0 148321.0 True False 93162.67763986358 106665.6060855337 137216.96027915674 141800.17095941803 138363.7438660767 140461.10641442717 161887.18501323176 150361.4507755825 127775.894696608 143128.3269353987 0.6509031414998148 0.7452445533977174 0.9586988349349597 0.9907205232924986 0.9667111104325804 0.9813648312805654 1.1310632107528225 1.0505359350944448 0.8927365912289321 1.0 17.12694970265018 -5.17009240020263 1.8234903994322857 1.009120712647113 0.6305331488099897 0.8168115051582536 0.057631199448074516 0.18581791363381117 1.0225416020202391 0.017248786236145647 0.09203418537633043 6.759391477325585e-06 5.17009240020263 -0.3785875638371232 GPLS(ph)PFNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GPLSPFNSR 9 0 A1L390-3;A1L390;A0A0U1RR71;G3V3I3;G3V278 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 GPLS(1)PFNSR;GPLS(1)PFNSR;GPLS(0.968)PFNS(0.032)R 91.31299999999999 0.0078972 20497300.0 50039.0 58235.0 75283.0 81841.0 90124.0 84750.0 90334.0 92355.0 82243.0 71139.0 True False 58509.614384700144 64016.18593829281 77078.03223236738 77255.71410210179 72464.84916054728 80305.56080615174 81776.909558476 89930.7791082112 83445.64828653034 84035.93756398575 0.6962451551177182 0.7617715443413753 0.91720321646533 0.9193175722384077 0.8623078561522786 0.9556097442835851 0.9731183102016361 1.0701466743289092 0.9929757518679916 1.0 16.358718800985073 -3.570609941248803 0.3587705095257198 1.0231963463047091 1.1648726242350485e-15 0.8515458331396593 0.0415934012396092 5.760217408669185 0.29953091921057584 0.039066404140541494 3.0284519904405576 0.00026877573536326265 3.570609941248803 -1.023196346304708 GPLS(ph)PFNSR ddPTM_PC-9_Lapatinib_30min_R1 5 GPLSPFNSR 9 0 A1L390-3;A1L390;A0A0U1RR71;G3V3I3;G3V278 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 GPLS(0.89)PFNS(0.11)R;GPLS(0.993)PFNS(0.007)R;GPLS(0.994)PFNS(0.006)R;GPLS(0.996)PFNS(0.004)R;GPLS(0.956)PFNS(0.044)R 105.17 0.0026544 87866000.0 190604.0 179226.0 173073.0 161798.0 165073.0 162563.0 151473.0 157146.0 168702.0 131435.0 True False 187885.95200750735 178811.01320861222 158843.60602109978 173697.1646623053 155363.73068600486 155610.55944286165 159315.53077691895 164447.5768496777 149701.00424918372 154153.36462387128 1.2188248531969599 1.1599553058404188 1.030425812687725 1.1267815340010268 1.0078517005781018 1.0094528901302016 1.0334872103871569 1.0667790304215798 0.9711173324983781 1.0 17.234006853166356 -1.5228787477669872 0.458710138967228 1.012699470314456 6.2479325362886815 0.7529210234282058 0.03786011996178151 43.54226708625299 0.5141528114647447 0.022543050453944783 214.6695270002269 0.02999999982822833 1.5228787477669872 5.235233065974225 GPLSPFNS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 GPLSPFNSR 9 0 A1L390-3;A1L390;A0A0U1RR71;G3V3I3;G3V278 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 GPLS(0.098)PFNS(0.902)R 88.134 0.010353 45422000.0 27370.0 33986.0 43390.0 71255.0 55093.0 55029.0 44850.0 60184.0 53433.0 51956.0 True False 36073.09066863395 44971.30986754683 42814.62024947762 54828.26062877583 47444.28792440266 51588.02793085186 48841.563114037344 50883.94569073646 56257.35929436853 50137.03625417561 0.7194898893855067 0.8969678550514928 0.8539519574396831 1.0935680432089665 0.9462922316324853 1.0289405155366638 0.9741613538229361 1.0148973591652746 1.122071895298422 1.0 15.613589096347992 -3.883760580978236 0.6143392046449879 1.0296991940500504 8.00592573205629e-14 0.7021088843294573 0.06142877470741834 5.166865053418629 0.6485856616293556 0.027199153457044045 4.818665874612565 0.00013068911560245336 3.883760580978236 -1.0296991940499702 GPLSPFNS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPLSPFNSR 9 0 A1L390-3;A1L390;A0A0U1RR71;G3V3I3;G3V278 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 GPLS(0.397)PFNS(0.603)R 84.31 0.013306 26043000.0 34816.0 41623.0 51015.0 62122.0 78453.0 65020.0 71202.0 70272.0 65138.0 52774.0 True False 40709.66115265533 45755.0563631761 52231.39107546491 58641.50574224138 63080.69782957273 61610.23673883171 64457.23110216081 68427.43445933839 66090.52002101099 62341.50844124585 0.6530105249381704 0.7339420797990194 0.837826873000526 0.94064945184168 1.011857098212879 0.9882699068293586 1.0339376238049955 1.0976223734436623 1.0601366837842625 1.0 15.927905442988449 -5.331567077738393 0.7372317393116097 1.0534197345635796 0.5525563012483518 0.9627449008559796 0.026903051396354634 0.26439067363641927 0.18033111920258746 0.012646399569976643 0.09719684430320696 4.6605043992668315e-06 5.331567077738393 -0.5008634333152279 GPMSTTVAGSQEGS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 GPMSTTVAGSQEGSK 15 0 A0A6I8PIV6;A0A6I8PLG0;A0A6I8PRQ0;A0A6I8PUE4;H0Y5C0;A0A6I8PRM6;B1ALU3;A0A6I8PTT2;A0A6I8PRJ0;O95490-3;O95490-4;O95490-2;O95490-5;O95490;O95490-7;O95490-6 A0A6I8PIV6 ADGRL2;LPHN2 Latrophilin-2 1 GPMSTTVAGSQEGS(1)K 65.949 0.028359 5777200.0 1351.3 1574.6 52124.0 81836.0 48377.0 25012.0 6858.4 73046.0 16932.0 25763.0 True False 1780.9852912139236 2083.5586570187493 51432.801702783414 62969.974553596316 41660.68859780422 23447.995686028575 7468.784313518702 61758.4191300934 17826.9909526369 24861.045211646913 0.07163758707858216 0.08380816813134803 2.068810915427166 2.532877198746902 1.6757416368917186 0.9431621030576642 0.3004211709497927 2.484144113987645 0.71706522396272 1.0 14.601599331207792 -5.246155788689195 24.116116196652087 1.5036790285623298 0.07772230419946483 0.3801291216468101 0.7073950217750885 533.4763145263141 841770.9835810517 0.18709525256896842 0.49049495286932243 5.6734105418378475e-06 5.246155788689195 -1.425956724362865 GPNQPVESDESLGGLS(ph)AALR ddPTM_PC-9_Lapatinib_30min_R1 1 GPNQPVESDESLGGLSAALR 20 0 D3YTB5;P51617-4;P51617-2;P51617-3;P51617;H7C3C1;H7C2I6;H7C224 D3YTB5 IRAK1 Interleukin-1 receptor-associated kinase 1 1 GPNQPVES(0.003)DES(0.341)LGGLS(0.656)AALR 76.533 0.02422 0.0 5037.7 5673.1 6213.6 3879.7 6952.7 4244.6 4914.2 5747.3 3660.3 3913.2 True False 4965.861474198964 5659.964285504226 5702.741793189625 4165.0260802998 6543.7558555341275 4063.0683526458724 5168.633230634734 6014.340539550187 3248.0384693322394 4589.591405988758 1.0819833477374974 1.2332174663999032 1.2425380145492615 0.9074938729545813 1.4257817911623822 0.8852788828530904 1.1261641338900907 1.3104304953382855 0.7076966514043092 1.0 12.164150006320252 -8.263284549924286 24.9993243478938 0.8538483291500234 1.1486379388615888 0.32526257881479315 0.17150320781441747 187.6186419444666 2541849.1519370433 0.1311887793164264 0.040616237470363734 5.454003974327653e-09 8.263284549924286 0.2947896097115654 GPPAS(ph)SPAPAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GPPASSPAPAPK 12 0 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 GPPAS(0.571)S(0.429)PAPAPK;GPPAS(0.528)S(0.472)PAPAPK;GPPAS(0.5)S(0.5)PAPAPK 86.463 0.009108499999999999 200460000.0 112313.0 147761.0 208721.0 182435.0 237553.0 211687.0 205283.0 226682.0 212452.0 167457.0 True False 131325.37261713523 162429.7355615705 213697.7002188005 172213.7584122504 191006.19493847855 200585.76106633467 185837.1081197839 220731.83768943232 215558.70858030417 197815.62851111777 0.6638776400306227 0.8211167984254667 1.080287244376094 0.8705771111637498 0.965576867591852 1.0140036081884258 0.9394460362839296 1.1158463026950705 1.0896950367507954 1.0 17.593796885795655 -4.239896612981662 0.9289097083453219 1.0154090166901175 1.431144849756495e-16 0.6868506391691681 0.07410488634804759 3.008322140679638 1.016728068527213 0.025766860391157578 3.9210115506177816 5.7557694138342574e-05 4.239896612981662 -1.0154090166901173 GPPASS(ph)PAPAPK ddPTM_PC-9_AZD4547_30min_R2 4 GPPASSPAPAPK 12 0 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 GPPAS(0.259)S(0.741)PAPAPK;GPPAS(0.114)S(0.886)PAPAPK;GPPAS(0.152)S(0.848)PAPAPK;GPPAS(0.124)S(0.876)PAPAPK 138.24 6.8806e-05 448020000.0 139210.0 154481.0 233024.0 290277.0 246339.0 234247.0 264702.0 330773.0 270821.0 277234.0 True False 183475.88425211995 204413.9622093954 229933.94950482302 223358.12238494394 212139.0819706574 219599.49805953668 288259.9652042796 279659.63325737737 285136.0451679705 267528.1220434619 0.6858190565188992 0.7640840172166531 0.8594758104251506 0.8348958632044589 0.7929599338950761 0.8208464081539104 1.0774940705390577 1.0453466765334847 1.0658170923864523 1.0 18.02933102725963 -7.2222417702635 5.55813119689574 1.0513095892299429 0.7950843036276847 0.8726308725233441 0.0475869441812806 0.0698102506069774 5.861474173479524 0.019908853279525393 0.015004837550529608 5.994572675235654e-08 7.2222417702635 -0.2562252856022582 GPPASS(ph)PAPAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GPPASSPAPAPK 12 0 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 GPPAS(0.115)S(0.885)PAPAPK;GPPAS(0.318)S(0.682)PAPAPK 152.67 0.00020357 132416000.0 145966.0 170251.0 221967.0 231097.0 269160.0 230991.0 236310.0 280970.0 223277.0 191333.0 True False 170675.1608400872 187152.39413033862 227259.53509453512 218149.38431658252 216420.03018122702 218877.42532358482 213925.0060637566 273594.8352123223 226542.0037264162 226020.15830880564 0.7551324718872997 0.8280340812549871 1.005483478973748 0.9651766725095844 0.9575253455293036 0.9683978055821822 0.9464864004363551 1.2104886451699435 1.0023088445805688 1.0 17.786091924047234 -3.6316264461149292 0.4813666767806494 1.040730594171201 4.998163568469525e-13 0.593510859956199 0.07205408532521934 9.482564223967225 0.7207856088281375 0.04539257449258849 7.101078427959325 0.0002335466025422613 3.6316264461149292 -1.0407305941707012 GPPASS(ph)PAPAPK ddPTM_PC-9_Lapatinib_30min_R1 4 GPPASSPAPAPK 12 0 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 GPPAS(0.087)S(0.913)PAPAPK;GPPAS(0.218)S(0.782)PAPAPK;GPPAS(0.142)S(0.858)PAPAPK;GPPAS(0.036)S(0.964)PAPAPK 160.67 0.00013769999999999999 316387000.0 196631.0 180055.0 189720.0 185652.0 173469.0 160801.0 162751.0 140371.2 173974.0 127394.3 True False 193827.00588229072 179638.09371004664 174121.95394037865 199305.4673969169 163265.89447317575 153923.916075439 171177.45043324106 146893.35840225974 154379.21609256262 149414.23501276562 1.2972459141241166 1.2022823240014497 1.165363888691744 1.3339121763056156 1.0927064242521918 1.0301824057278617 1.1456569075805665 0.9831282701391169 1.0332296389254532 1.0 17.188958077744694 -6.433057777646311 5.5330788306690195 1.0456423735348777 1.2395325245418005 0.7366619752268045 0.059720441120848594 0.12473838495653623 5.994392962127795 0.018708498935274362 0.0211156156800117 3.689285138130495e-07 6.433057777646311 0.19389015100692286 GPPASSPAPAPKFS(ph)PVTPK ddPTM_PC-9_AZD4547_30min_R2 2 GPPASSPAPAPKFSPVTPK 19 1 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 GPPASSPAPAPKFS(0.992)PVT(0.008)PK;GPPASS(0.001)PAPAPKFS(0.868)PVT(0.131)PK 128.8 1.6654e-05 196133000.0 114798.0 59832.0 115707.0 215834.0 185920.0 125640.0 107735.0 112448.0 92208.0 149067.0 True False 151301.37605326428 79171.52392146942 114172.64957838919 166076.80590205896 160108.21721280256 117783.71093845484 117323.2062896503 95071.74539797832 97081.92663363718 143848.20970246344 1.0518127154047798 0.5503824071584089 0.7937022630628815 1.154528139387854 1.1130358698517793 0.8188055394090716 0.815604215946256 0.6609171264253154 0.6748914486627401 1.0 17.134187740217172 -10.790879949373258 5.765613618534457 1.0000091924562908 0.8472945510934982 0.053875234150721374 0.19082526972064237 2.4282056815229732e-05 3.0830714356628202e-06 0.19897278700820561 0.04825508556885641 1.618527380129258e-11 10.790879949373258 -0.15271464136279267 GPPASSPAPAPKFS(ph)PVTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GPPASSPAPAPKFSPVTPK 19 1 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 GPPASSPAPAPKFS(0.926)PVT(0.073)PK;GPPASSPAPAPKFS(0.884)PVT(0.116)PK 64.275 0.0053831 129354000.0 89683.0 46326.0 66147.0 109803.0 116672.0 135772.0 114717.0 161189.0 144615.0 110927.0 True False 104864.56058000878 50924.939122131866 67724.19534389443 103651.0938961293 93810.95913695995 128651.87730705403 103850.17528084306 156957.95954386287 146729.7207902991 131037.18700235116 0.8002656572452767 0.38862967289749695 0.5168318772187873 0.7910051815617006 0.7159109660624562 0.9817966964198162 0.7925244555118518 1.1978123396455895 1.1197563389976188 1.0 16.99961676628022 -6.745786728847696 0.8065987813596116 1.0973943317868216 0.554464434940761 0.6548747598486415 0.14159117315230113 0.36978785397565095 0.5270114439392064 0.09353635061954578 0.0910089614212622 1.7956151920449515e-07 6.745786728847696 -0.5429298968460605 GPPASSPAPAPKFS(ph)PVTPK ddPTM_PC-9_Lapatinib_30min_R1 2 GPPASSPAPAPKFSPVTPK 19 1 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 GPPASSPAPAPKFS(0.974)PVT(0.026)PK;GPPASSPAPAPKFS(0.947)PVT(0.053)PK 87.319 0.00055809 109242000.0 286220.0 100234.0 140603.0 139569.0 108007.0 115338.0 73936.0 65376.0 136379.0 85764.0 True False 282138.4503136799 100001.91433135846 129043.16408327564 149833.3698485356 101654.24060993205 110405.26260600994 77764.0443083736 68413.60762682182 121018.56088546332 100588.19312665332 2.804886354389841 0.9941714949133577 1.282885794765136 1.4895721375557103 1.0105981373175323 1.0975966380765552 0.7730931622408088 0.6801355656193206 1.2031090043846953 1.0 16.618101448394555 -4.760123181518462 24.999975916785253 1.0602301292116287 2.8048884606492703 0.8476376479015328 0.2220574763335791 13.326247257050905 253023.57058675573 0.06104437424944941 0.3696796623286968 1.737307995894243e-05 4.760123181518462 1.7446583314376416 GPPDFS(ph)SDEEREPTPVLGSGAAAAGR ddPTM_PC-9_AZD4547_30min_R2 3 GPPDFSSDEEREPTPVLGSGAAAAGR 26 1 P42166;G5E972;P42167;P42167-2;P42167-3 P42166;G5E972 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 GPPDFS(0.543)S(0.454)DEEREPT(0.003)PVLGSGAAAAGR;GPPDFS(0.549)S(0.451)DEEREPT(0.001)PVLGSGAAAAGR;GPPDFS(0.534)S(0.445)DEEREPT(0.019)PVLGS(0.002)GAAAAGR 70.767 0.00011323 235413000.0 11570.0 10497.699999999999 27511.2 38834.8 28098.0 22657.5 28742.899999999998 29632.2 18646.0 28939.8 True False 15249.019329049876 13890.876231287773 27146.383512501245 29882.036851678968 24197.07770678427 21240.72294323494 31300.962417624596 25053.22437021536 19631.589493436557 27926.626410589553 0.5460387196381002 0.4974061681156183 0.9720609683884894 1.070019572444595 0.8664518710934926 0.7605903638679619 1.1208286299040948 0.8971088738708295 0.7029703196084012 1.0 14.769353683397327 -5.259426308908858 24.965612139856777 0.9244675450282706 0.5217224032005416 0.6345615841816477 0.12203565050387284 105.20048120126512 1304646.5683351487 0.03213448261768982 0.07674214026124071 5.502672819464817e-06 5.259426308908858 -0.4027451418277289 GPPDFS(ph)SDEEREPTPVLGSGAAAAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GPPDFSSDEEREPTPVLGSGAAAAGR 26 1 P42166;G5E972;P42167;P42167-2;P42167-3 P42166;G5E972 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 GPPDFS(0.528)S(0.472)DEEREPTPVLGSGAAAAGR;GPPDFS(0.535)S(0.46)DEEREPT(0.004)PVLGSGAAAAGR;GPPDFS(0.633)S(0.359)DEEREPT(0.006)PVLGS(0.002)GAAAAGR;GPPDFS(0.746)S(0.252)DEEREPT(0.001)PVLGS(0.001)GAAAAGR;GPPDFS(0.545)S(0.455)DEEREPTPVLGSGAAAAGR 64.318 0.00025388 251673400.0 17431.199999999997 17871.2 21426.699999999997 17804.4 26222.8 16685.6 27977.899999999998 17743.1 19848.699999999997 13393.140000000001 True False 20381.957878106776 19645.33462935378 21937.59378921225 16806.87719064361 21084.630581944857 15810.577762679937 25327.630769545023 17277.362425368425 20138.949687448803 15821.2102619621 1.2882679352988426 1.2417087128021913 1.3865939094403776 1.0623003494904106 1.3326812698164598 0.9993279591696138 1.600865569079667 1.09203797555913 1.2729082891886951 1.0 13.949572344224032 -9.446136581471526 1.178358462390946 0.9991853073769082 1.2536483689780091 0.17288142946239482 0.16550975728562958 16.025333959459772 18.676701820917003 0.1910589398300721 0.0448275880630132 3.579838368960678e-10 9.446136581471526 0.2544630616011009 GPPDFS(ph)SDEEREPTPVLGSGAAAAGR ddPTM_PC-9_Lapatinib_30min_R1 3 GPPDFSSDEEREPTPVLGSGAAAAGR 26 1 P42166;G5E972;P42167;P42167-2;P42167-3 P42166;G5E972 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 GPPDFS(0.532)S(0.467)DEEREPTPVLGSGAAAAGR;GPPDFS(0.547)S(0.453)DEEREPTPVLGSGAAAAGR;GPPDFS(0.545)S(0.453)DEEREPT(0.002)PVLGSGAAAAGR 86.182 5.5306e-07 260141000.0 24274.199999999997 27034.4 21509.6 18444.100000000002 21646.6 23216.6 17034.9 17394.3 23255.5 10513.8 True False 23928.045456656902 26971.803507788587 19741.1637174571 19800.54064171393 20373.389546853043 22223.680138537933 17916.88376959415 18202.502679014095 20636.220698728488 12331.09632124211 1.9404637538543397 2.187299718138259 1.6009252708090578 1.6057404894003313 1.6521961240183414 1.8022469016201266 1.4529838469211944 1.4761463380719548 1.6735106239645205 1.0 13.590013450734395 -1.522878745280338 0.05326241333799615 1.3678280381166158e-12 4.821627694953858 0.6985980593794816 0.163923200200041 254.16200090603388 1.022496205100162 20.784324095696622 98.64162281987208 0.029999999999999964 1.522878745280338 4.8216276949524906 GPPDFSSDEEREPT(ph)PVLGSGAAAAGR ddPTM_PC-9_AZD4547_30min_R2 2 GPPDFSSDEEREPTPVLGSGAAAAGR 26 1 P42166;G5E972;P42167;P42167-2;P42167-3 P42166;G5E972 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 GPPDFS(0.041)S(0.035)DEEREPT(0.911)PVLGS(0.012)GAAAAGR;GPPDFS(0.02)S(0.017)DEEREPT(0.514)PVLGS(0.449)GAAAAGR 66.711 0.00030813 172237000.0 51709.0 53361.0 103572.0 83728.0 87776.0 63181.0 67940.0 75258.0 57464.0 59022.0 True False 68151.3863859843 70608.89971877134 102198.5676072575 64425.803184704906 75589.8175240479 59230.28208215943 73986.52838278034 63628.605356796565 60501.42972491889 56955.65774489864 1.196569209879565 1.2397170450567851 1.7943532153556974 1.1311572148506237 1.3271696002987212 1.0399367583014967 1.2990198219492444 1.117160399442417 1.0622549562310661 1.0 15.797551540097139 -6.397537287363935 1.7283893054879076 1.1247332566746049 1.378403913220427 0.271292230376893 0.1856000597067116 0.5168052268158522 3.0743813624044747 0.06906172672594192 0.08291326394161666 4.003710920625255e-07 6.397537287363935 0.2536706565458222 GPPDFSSDEEREPT(ph)PVLGSGAAAAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GPPDFSSDEEREPTPVLGSGAAAAGR 26 1 P42166;G5E972;P42167;P42167-2;P42167-3 P42166;G5E972 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 GPPDFS(0.001)S(0.001)DEEREPT(0.969)PVLGS(0.029)GAAAAGR;GPPDFS(0.017)S(0.014)DEEREPT(0.915)PVLGS(0.054)GAAAAGR;GPPDFS(0.209)S(0.176)DEEREPT(0.604)PVLGS(0.011)GAAAAGR 64.962 0.00036641 94635000.0 47503.3 59869.0 67814.0 45516.0 95574.0 43926.0 54961.0 36318.7 38271.4 39668.1 True False 55544.670457058026 65812.39865956295 69430.94294602721 42965.88608486302 76846.96078369947 41622.443232696394 49754.69619681835 35365.3726078435 38831.04682262459 46859.61251749319 1.1853420776008896 1.404458874579778 1.4816798350628253 0.916906559328108 1.6399401671324467 0.8882370339097084 1.0617820661287884 0.7547090278358839 0.8286676892201904 1.0 15.516057404143108 -6.795255671135829 24.97853950785043 0.9010420362891534 1.3160015781041594 0.5362455140472191 0.19468036623549462 144.4010158738682 106661.40481204158 0.06609269313332591 0.05829132698454577 1.602301830606386e-07 6.795255671135829 0.41495954181500605 GPPDFSSDEEREPT(ph)PVLGSGAAAAGR ddPTM_PC-9_Lapatinib_30min_R1 3 GPPDFSSDEEREPTPVLGSGAAAAGR 26 1 P42166;G5E972;P42167;P42167-2;P42167-3 P42166;G5E972 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 GPPDFS(0.002)S(0.002)DEEREPT(0.579)PVLGS(0.417)GAAAAGR;GPPDFS(0.009)S(0.008)DEEREPT(0.941)PVLGS(0.042)GAAAAGR;GPPDFSSDEEREPT(0.753)PVLGS(0.246)GAAAAGR 90.084 4.1713000000000003e-07 147887700.0 194936.0 201220.0 94017.2 43142.9 67742.5 74609.1 76729.8 64466.1 113988.2 23908.42 True False 192156.17689311606 200754.08745291978 86287.46873288704 46315.77278649543 63758.01933687936 71418.24271530678 80702.49360220523 67461.43035106851 101149.64856704025 28040.958541032847 6.8526964444503715 7.159316153873722 3.0771939770397294 1.6517186000871087 2.2737460719675857 2.5469258695561052 2.8780219293898885 2.405817556213386 3.607210802691574 1.0 14.775248046257413 -5.304335467378996 4.365897009810902 2.4268117898858472 7.05984633509521 0.8836470657016282 0.6670707958948817 0.056673822318714616 2.4403084119581275 0.17050111988990527 0.3992231481393632 4.962088807039431e-06 5.304335467378996 4.633034545209362 GPPEDRDAEPQPGS(ph)PAAESLEEPDAAAGLSSTK ddPTM_PC-9_AZD4547_30min_R2 3 GPPEDRDAEPQPGSPAAESLEEPDAAAGLSSTK 33 1 Q9H9J4-2;Q9H9J4;C9JPC9 Q9H9J4-2 USP42 Ubiquitin carboxyl-terminal hydrolase 42 1 GPPEDRDAEPQPGS(0.608)PAAES(0.392)LEEPDAAAGLSSTK;GPPEDRDAEPQPGS(0.722)PAAES(0.278)LEEPDAAAGLSSTK;GPPEDRDAEPQPGS(1)PAAESLEEPDAAAGLSSTK 107.13 3.5496e-21 28506900.0 29710.5 27291.4 37883.9 51261.0 42150.1 38062.1 30649.5 37948.7 30784.4 32125.199999999997 True False 39157.82098320969 36112.81133758513 37381.53473309947 39443.5684245552 36298.28617868631 35682.07087002991 33377.246124051 32084.600389373438 32411.60053640182 31000.506526149853 1.263134876527869 1.1649103638717289 1.2058362563065552 1.2723523853161356 1.1708933255031695 1.1510157371116183 1.0766677665700817 1.0349701983839883 1.0455184178704198 1.0 14.92000416784878 -7.186762956772217 1.1979639608321675 1.0215641766243602 1.2209278759938256 0.8798215933442672 0.031441320051775655 0.1583377135072619 0.44879770771447397 0.020222798654231298 0.012328637787387022 6.504846359194117e-08 7.186762956772217 0.1993636993694654 GPPEDRDAEPQPGS(ph)PAAESLEEPDAAAGLSSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GPPEDRDAEPQPGSPAAESLEEPDAAAGLSSTK 33 1 Q9H9J4-2;Q9H9J4;C9JPC9 Q9H9J4-2 USP42 Ubiquitin carboxyl-terminal hydrolase 42 1 GPPEDRDAEPQPGS(1)PAAESLEEPDAAAGLSSTK;GPPEDRDAEPQPGS(0.997)PAAES(0.003)LEEPDAAAGLSSTK;GPPEDRDAEPQPGS(0.999)PAAES(0.001)LEEPDAAAGLSSTK;GPPEDRDAEPQPGS(0.995)PAAES(0.005)LEEPDAAAGLSSTK 122.06 2.461e-24 20072000.0 87162.0 51268.6 88394.8 109953.0 128072.0 116115.0 118285.0 122167.0 104580.0 92800.0 True False 101916.80507202871 56358.207785626444 90502.46727114587 103792.68988243562 102977.21097254475 110025.72499122484 107080.1884907598 118960.24569663609 106109.28465407803 109623.90539560429 0.9296950761263006 0.5141050903290141 0.8255723689513331 0.9468070810638854 0.9393682025916397 1.0036654376996557 0.97679596529913 1.0851670104922768 0.967939285424626 1.0 16.742202911741096 -5.687013664528597 2.8986291581971426 0.9940056625888994 0.7125036406303185 0.5386697593575133 0.10098303630467911 0.17183960720994926 2.9064517857544785 0.027328295938437906 0.05114112668926589 2.0558259109948906e-06 5.687013664528597 -0.281502021958581 GPPEDRDAEPQPGS(ph)PAAESLEEPDAAAGLSSTK ddPTM_PC-9_Lapatinib_30min_R1 1 GPPEDRDAEPQPGSPAAESLEEPDAAAGLSSTK 33 1 Q9H9J4-2;Q9H9J4;C9JPC9 Q9H9J4-2 USP42 Ubiquitin carboxyl-terminal hydrolase 42 1 GPPEDRDAEPQPGS(0.994)PAAES(0.006)LEEPDAAAGLSSTK 108.52 1.2597e-08 0.0 2140.3 2276.7 3977.7 2446.4 2560.8 2329.2 1048.9 2506.1 3990.0 923.19 True False 2109.7789295170505 2271.4284410300306 3650.6688603660295 2626.316416951165 2410.1787787265102 2229.585545630394 1103.2069096928838 2622.5425549678475 3540.6041834373236 1082.7621614266486 1.9485155694184986 2.0978092160490664 3.3716258199823903 2.4255709245424018 2.225954013345697 2.059164630109247 1.0188820306015285 2.422085522006405 3.269974062237472 1.0 10.080500661298816 -6.497303842832863 2.8600310861159297 1.9892053365252016 2.495062132976711 0.10169255000131638 0.7057330696162023 0.7193427516253413 11.84281836189491 0.2514620369525525 0.27265607554768917 3.1819705598994116e-07 6.497303842832863 0.5058567964515093 GPPEDRDAEPQPGSPAAES(ph)LEEPDAAAGLSSTK ddPTM_PC-9_AZD4547_30min_R2 1 GPPEDRDAEPQPGSPAAESLEEPDAAAGLSSTK 33 1 Q9H9J4-2;Q9H9J4;C9JPC9 Q9H9J4-2 USP42 Ubiquitin carboxyl-terminal hydrolase 42 1 GPPEDRDAEPQPGS(0.44)PAAES(0.557)LEEPDAAAGLS(0.001)S(0.001)T(0.001)K 45.327 0.029051 0.0 2984.1 957.21 2881.0 4218.3 2659.2 2532.8 1349.0 4795.2 2666.6 3391.0 True False 3932.981726864107 1266.6094132382314 2842.7960575880397 3245.836107085332 2290.0159811332023 2374.4236156074344 1469.0583866407226 4054.212022733941 2807.551032028203 3272.2821221400686 1.2019078979326945 0.3870721918102435 0.8687502945891641 0.9919181739019981 0.6998222939394769 0.7256170241380545 0.4489400155020742 1.2389555274905488 0.8579795162013928 1.0 11.676081421287195 -7.77495714272163 24.999749682209746 1.0363505287583255 0.755587021589926 0.2118993612048804 0.23997726057464505 362.20174991948176 669845.9621492325 0.12479606425529098 0.06047297600888858 1.678969694925518e-08 7.77495714272163 -0.2807635071683995 GPPNS(ph)PDLK ddPTM_PC-9_AZD4547_30min_R2 2 GPPNSPDLK 9 0 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 GPPNS(1)PDLK;GPPNS(1)PDLK 94.402 0.0057588 59915000.0 145622.0 145359.0 145138.0 181477.0 166457.0 161982.0 139986.0 179717.0 140298.0 150883.0 True False 191926.76687423504 192343.4540998277 143213.37528851535 139640.28144170027 143347.31880696822 151853.23993340333 152444.48281118457 151945.8671358181 147713.86585595628 145600.63209521075 1.3181726213161686 1.3210344717051161 0.9836040766283601 0.9590637034486711 0.984524014382238 1.0429435487210241 1.0470042651428773 1.043579721799958 1.0145139051275798 1.0 17.151657093150938 -5.258531424260753 24.995328038052644 1.0108148160396533 1.3196035835018465 0.9525994473779686 0.02767674482180913 52.650724552724704 452553.6797459644 0.008412520782847361 0.02031956355359815 5.514023031028677e-06 5.258531424260753 0.3087887674621932 GPPNS(ph)PDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GPPNSPDLK 9 0 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 GPPNS(1)PDLK;GPPNS(1)PDLK;GPPNS(1)PDLK 103.46 0.0028482 39006600.0 119101.0 126288.0 126077.0 137289.0 151997.0 143134.0 149182.0 129632.0 129365.0 119040.0 True False 139262.44694802398 138825.0380316837 129083.15382968492 129597.14242694332 122214.27896959419 135627.80106699382 135050.40097585114 126229.29735645765 131256.7183904649 140621.00967987822 0.9903388353209311 0.9872282836520445 0.9179506968662857 0.921605830607883 0.8691039784724438 0.9644917311840431 0.9603856584680448 0.8976560305164705 0.9334075945640626 1.0 17.10145263283419 -5.253699394961904 23.60140297973106 0.9288231349714591 0.988783582622814 0.28543652033982403 0.034739759107287264 313.1959374646643 955008.0390453296 0.008734618611945227 0.022133819778143198 5.575715489600041e-06 5.253699394961904 0.05996044765135489 GPPNS(ph)PDLK ddPTM_PC-9_Lapatinib_30min_R1 3 GPPNSPDLK 9 0 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 GPPNS(1)PDLK;GPPNS(1)PDLK;GPPNS(1)PDLK 97.163 0.004871899999999999 69806600.0 310745.0 297555.0 284901.0 276422.0 305114.0 330067.0 332978.0 308313.0 352514.0 279235.0 True False 306313.7193163468 296866.0296792242 261477.5395296635 296750.99599676 287167.794397204 315950.80383375706 350217.9715661329 322638.3475319426 312810.1611830137 327500.39769275085 0.9353079308432455 0.9064600585851297 0.7984037313291216 0.9061088111262727 0.8768471623860883 0.9647341073770872 1.069366553547501 0.9851540633383608 0.9551443704702948 1.0 18.321137132992277 -6.874997684572699 4.043529067789554 1.003052964101171 0.8821721771863913 0.6317094025948011 0.042717945369548184 0.14842777400405324 4.441749277637277 0.016132048802139375 0.014204910079692011 1.3335285418096344e-07 6.874997684572699 -0.12088078691477966 GPPQEEEEEEDEEEEATKEDAEAPGIR ddPTM_PC-9_Lapatinib_30min_R1 1 GPPQEEEEEEDEEEEATKEDAEAPGIR 27 1 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 0 152.96 3.6444999999999997e-10 6918900.0 11555.0 15322.0 15858.0 15851.0 14355.0 10499.0 13344.0 16134.0 15763.0 16098.0 False True 11390.223581072521 15286.522850380872 14554.21645365023 17016.73541738591 13510.667123015877 10049.982244364372 14034.887027306542 16883.644540062753 13987.604948251257 18880.517850763328 0.6032791934577166 0.8096453164690526 0.7708589652408189 0.9012854176930286 0.7155877412795459 0.5322937815478433 0.7433528644840173 0.8942363060968773 0.7408485857651276 1.0 14.20461071471967 -9.03196631345741 0.8237061548177264 1.0001494234187345 0.7375993225686327 0.34010856767017217 0.1077535837419277 2.1808211692854846 2.329052358533094 0.11860090625335032 0.038415616186811136 9.290384459028418e-10 9.03196631345741 -0.2625501008501018 GPPQS(ph)PVFEGVYNNSR ddPTM_PC-9_AZD4547_30min_R2 4 GPPQSPVFEGVYNNSR 16 0 H3BUF6;Q8WWM7-7;H3BSK9;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 GPPQS(0.979)PVFEGVY(0.011)NNS(0.009)R;GPPQS(0.898)PVFEGVY(0.007)NNS(0.095)R;GPPQS(0.997)PVFEGVY(0.003)NNSR;GPPQS(0.701)PVFEGVY(0.287)NNS(0.012)R 122.97 4.9228000000000004e-05 714140000.0 186183.0 183734.0 265295.0 311443.0 278506.0 257680.0 206179.0 279135.0 208556.0 243748.0 True False 245385.32115302465 243122.42238580156 261777.01495932625 239644.62809638403 239840.24926349378 241567.22886517877 224528.53157835276 236001.099634184 219579.84438448763 235214.45671111756 1.0432408134437017 1.0336202365503253 1.1129291057174768 1.0188346050120016 1.0196662765420812 1.0270084255997218 0.9545694372608701 1.0033443646877223 0.9335303937298726 1.0 17.843617208014493 -6.786710971649118 1.093855367055645 0.9714073256356857 1.0568891426058546 0.5569200480935388 0.030910470233377087 0.36320308112823874 0.9230904421276926 0.016503266521302348 0.014550034679791948 1.634139125895172e-07 6.786710971649118 0.08548181697016899 GPPQS(ph)PVFEGVYNNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GPPQSPVFEGVYNNSR 16 0 H3BUF6;Q8WWM7-7;H3BSK9;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 GPPQS(0.997)PVFEGVY(0.003)NNSR;GPPQS(0.997)PVFEGVY(0.003)NNSR;GPPQS(0.999)PVFEGVYNNSR;GPPQS(0.844)PVFEGVY(0.145)NNS(0.011)R 163.11 2.9875e-05 454021000.0 150977.0 158145.0 202154.0 215812.0 252915.0 257387.0 268493.0 243994.0 214191.0 194837.0 True False 176534.42416832663 173844.5904561058 206974.1180333141 203720.75331194414 203358.12131551895 243889.1726160825 243059.3993190141 237589.41603301239 217323.13816543913 230159.40577115677 0.7670093845473842 0.7553225551379649 0.8992642179442565 0.8851289506477954 0.8835533817710416 1.0596532946325774 1.0560480833039843 1.0322820187902428 0.9442287941146298 1.0 17.812273875860782 -5.829968666047582 0.7913236895755642 1.0214487525852622 0.73784368549749 0.7849740620727005 0.048728071110745765 0.4021894783593769 0.4627959439550312 0.024942812072905385 0.07831401484243902 1.4792151083448393e-06 5.829968666047582 -0.2836050670877722 GPPQS(ph)PVFEGVYNNSR ddPTM_PC-9_Lapatinib_30min_R1 3 GPPQSPVFEGVYNNSR 16 0 H3BUF6;Q8WWM7-7;H3BSK9;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 GPPQS(0.996)PVFEGVY(0.004)NNSR;GPPQS(0.985)PVFEGVY(0.012)NNS(0.003)R;GPPQS(1)PVFEGVYNNSR 161.14 4.9228000000000004e-05 472970000.0 160603.0 164234.0 191130.0 177190.0 199889.0 195496.0 181393.0 169002.0 220541.0 185517.0 True False 158312.77176901672 163853.72626350712 175416.02918313566 190221.1436885127 188131.9220168943 187135.09180343448 190784.64197723448 176854.4498921339 195701.35018031357 217583.366264136 0.7275959301816869 0.7530618221275076 0.8062014674880469 0.8742448788920434 0.8646429423677128 0.8600615709578702 0.8768346829675889 0.8128123621244139 0.8994315766892829 1.0 17.731208744602768 -1.5228787452803376 0.09111676800382981 1.071665000133489 0.1643222282981583 0.7825318231946267 0.03432711555693704 82.20237174231443 0.5398036246161028 0.6927122180381571 9.31898998196989 0.029999999999999995 1.5228787452803376 -0.9073427718353309 GPPQSPVFEGVY(ph)NNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GPPQSPVFEGVYNNSR 16 0 H3BUF6;Q8WWM7-7;H3BSK9;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 GPPQS(0.006)PVFEGVY(0.994)NNSR;GPPQS(0.471)PVFEGVY(0.528)NNS(0.001)R 111.63 0.00063414 33986000.0 184900.0 268690.0 240450.0 208936.0 250130.0 196558.0 211155.0 173912.0 154920.0 157982.0 True False 216199.91805853506 295363.76748965145 246183.2399117027 197229.9932996517 201118.822073229 186250.152459417 191152.86977018588 169346.9942749953 157185.4119201544 186622.8860151762 1.1584855570230206 1.5826770970931852 1.3191481772052494 1.0568371195567778 1.0776750181479564 0.9980027446594686 1.0242734631948693 0.9074288684037604 0.8422622502331899 1.0 17.509766392652246 -5.804392570933415 2.570413622739265 0.9769833730309094 1.390650948229979 0.6934680481312407 0.11296767733544358 0.1477468328895701 1.9888612121588876 0.03344988367259105 0.058619424950901014 1.5689439508244848e-06 5.804392570933415 0.4136675751990695 GPPQSPVFEGVYNNS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 GPPQSPVFEGVYNNSR 16 0 H3BUF6;Q8WWM7-7;H3BSK9;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 GPPQS(0.178)PVFEGVY(0.319)NNS(0.503)R 107.34 0.00091777 123970000.0 28541.0 32525.0 36375.0 32020.0 50803.0 30638.0 37539.0 39893.0 29941.0 27250.0 True False 28134.000106221618 32449.690360830027 33384.38791156055 34374.857615588706 47814.86742254095 29327.684160666297 39482.58574026235 41746.57441655658 26568.729287292448 31960.126191657393 0.8802843874116331 1.0153179673395791 1.044563707645026 1.0755545021772046 1.4960788056907657 0.9176335532843344 1.2353701453960015 1.306208059574363 0.8313086477808629 1.0 14.963985484177007 -5.1372769595274805 1.4052893438179672 1.1441975301982459 0.871534076139797 0.13344808154268606 0.1834549973036787 1.2709449220447986 3.52907435597121 0.0537682669414437 0.4074561189695506 7.289924668109562e-06 5.1372769595274805 -0.27266345405844883 GPPS(ph)PGPAAQPPAPPR ddPTM_PC-9_AZD4547_30min_R2 2 GPPSPGPAAQPPAPPR 16 0 H9KV50;Q9NZV5-2;Q9NZV5 H9KV50 SEPN1 Selenoprotein N 1 GPPS(1)PGPAAQPPAPPR;GPPS(1)PGPAAQPPAPPR 102.63 0.001475 23826000.0 18024.2 9360.6 17064.199999999997 25327.7 13816.5 19158.8 7161.0 13314.0 12361.0 12194.2 True False 23755.520673350104 12386.230893490236 16837.91755844978 19488.790074064225 11898.317465150009 17960.797207319854 7798.315127304826 11256.627225283555 13014.37722451835 11767.284769625607 2.018776730437358 1.0525988905666912 1.4309093293903095 1.6561841117646623 1.011135338193109 1.5263331821187245 0.6627115158659443 0.9566036214522325 1.1059796273573501 1.0 13.522493845099795 -6.806324777322441 1.221497743737203 0.9465068196385314 1.4885196590132783 0.38484354160085443 0.3011954439795897 0.49762603010418016 1.5610541617881282 0.14968186717927745 0.12935899133963227 1.5619791149533915e-07 6.806324777322441 0.5420128393747469 GPPS(ph)PGPAAQPPAPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GPPSPGPAAQPPAPPR 16 0 H9KV50;Q9NZV5-2;Q9NZV5 H9KV50 SEPN1 Selenoprotein N 1 GPPS(1)PGPAAQPPAPPR;GPPS(1)PGPAAQPPAPPR;GPPS(1)PGPAAQPPAPPR;GPPS(1)PGPAAQPPAPPR 122.12 6.3655e-05 23403300.0 33132.1 32499.7 28812.5 40960.9 42115.299999999996 45249.8 44142.3 32155.0 38512.299999999996 25552.9 True False 38740.71014119637 35726.05543296527 29499.49927201475 38665.993570029525 33863.109292210676 42876.82083027971 39960.821781423496 31310.965321038682 39075.469529386566 30185.43849335489 1.283423798853373 1.1835526404835932 0.977275823854898 1.280948546715383 1.1218359242873148 1.4204471748760163 1.3238443360768335 1.0372870789315043 1.2945138941078744 1.0 14.881565138380845 -10.942761830226072 2.9725122118489273 0.9960605122734416 1.209252329344659 0.19648045416756899 0.12935730759126474 25478425.368997935 29183327.645754796 841938.2447126757 0.03201534080846402 1.1408752790772315e-11 10.942761830226072 0.21319181707121748 GPPS(ph)PGPAAQPPAPPR ddPTM_PC-9_Lapatinib_30min_R1 1 GPPSPGPAAQPPAPPR 16 0 H9KV50;Q9NZV5-2;Q9NZV5 H9KV50 SEPN1 Selenoprotein N 1 GPPS(1)PGPAAQPPAPPR 106.6 0.0010007999999999998 8250600.0 6648.3 12878.0 12764.0 4307.4 5653.6 12222.0 4792.0 6885.4 14797.0 13505.0 True False 6553.494022851099 12848.18178222197 11714.593190464839 4624.180565065172 5321.066363405264 11699.293550873548 5040.106312563923 7205.320820388504 13130.40604068222 15839.32125571863 0.413748412387622 0.8111573453681458 0.7395893423296406 0.2919431009959254 0.3359403018285361 0.7386234146017863 0.31820216480199504 0.4549008574333382 0.8289752969017922 1.0 13.951222894134322 -8.43492452796379 3.689991168449105 0.9950944458935266 0.5190991371276749 0.45429230008056143 0.18020096452374865 0.20496109456672224 5.077276250903149 0.18129051937822876 0.047859974148802456 3.6734613265101074e-09 8.43492452796379 -0.4759953087658517 GPPS(ph)PPAPVMHS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 4 GPPSPPAPVMHSPSR 15 0 G3V3A4;Q13573;G3V4X8 G3V3A4 SNW1 SNW domain-containing protein 1 2 GPPS(1)PPAPVMHS(0.949)PS(0.051)R;GPPS(1)PPAPVMHS(0.947)PS(0.053)R;GPPS(1)PPAPVMHS(0.824)PS(0.176)R;GPPS(1)PPAPVMHS(0.841)PS(0.159)R 104.78 0.0038723 67085500.0 140545.0 126378.4 187390.0 235267.0 219754.0 184183.0 146157.0 225296.0 177417.0 188836.0 True False 185235.38648239558 167227.74633569058 184905.0861615491 181029.827988916 189244.95033015378 172666.0078938028 159164.6898563735 190481.67998704236 186794.9004160159 182224.90911720527 1.0165206687701185 0.9176997104612703 1.0147080717851804 0.9934417246572991 1.0385240483694427 0.9475433887183103 0.8734518822231945 1.0453108793404662 1.025078850750702 1.0 17.475360655330952 GPPS(ph)PPAPVMHS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GPPSPPAPVMHSPSR 15 0 G3V3A4;Q13573;G3V4X8 G3V3A4 SNW1 SNW domain-containing protein 1 2 GPPS(1)PPAPVMHS(0.673)PS(0.327)R;GPPS(1)PPAPVMHS(0.864)PS(0.136)R;GPPS(1)PPAPVMHS(0.514)PS(0.486)R;GPPS(1)PPAPVMHS(0.894)PS(0.106)R 87.669 0.0078212 140858000.0 182840.0 185338.0 216385.0 246643.0 261673.0 223885.0 220387.0 210755.0 204041.0 189028.0 True False 213791.20074539035 203737.13178382974 221544.439044682 232824.3923373952 210400.0540853478 212144.07647298268 199510.34789629394 205222.9045633808 207024.71361735289 223297.28005517568 0.9574285933647001 0.9124031055527737 0.9921501909469718 1.0426655993295817 0.9422419029616436 0.9500522192682459 0.893474151798875 0.9190568936292964 0.9271259979799041 1.0 17.76860615249013 -6.50250862862202 24.689014042170232 0.9318862621364897 0.9752127037118941 0.16921901586788524 0.0396614650752676 1114.746700832525 1351098.344446526 0.012986707796640394 0.014549208093994069 3.1440639529466616e-07 6.50250862862202 0.04332644157540433 GPPS(ph)PPAPVMHS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 8 GPPSPPAPVMHSPSR 15 0 G3V3A4;Q13573;G3V4X8 G3V3A4 SNW1 SNW domain-containing protein 1 2 GPPS(1)PPAPVMHS(0.941)PS(0.059)R;GPPS(1)PPAPVMHS(0.818)PS(0.182)R;GPPS(1)PPAPVMHS(0.852)PS(0.148)R;GPPS(1)PPAPVMHS(0.944)PS(0.056)R;GPPS(1)PPAPVMHS(0.867)PS(0.133)R;GPPS(1)PPAPVMHS(0.96)PS(0.04)R;GPPS(1)PPAPVMHS(0.891)PS(0.109)R;GPPS(1)PPAPVMHS(0.952)PS(0.048)R 106.47 0.0020959 241936000.0 305943.0 259545.0 370275.0 286748.0 316545.0 341910.0 280913.0 288341.0 350379.0 259926.0 True False 301580.19671692495 258944.0394988971 339832.4188028342 307836.4044832861 297926.44545141485 327287.30633113836 295457.30062213494 301738.37550057255 310915.62736556045 304853.8627703759 0.9892615234601217 0.8494038328585677 1.1147387660257566 1.0097835129455346 0.9772762685176176 1.0735875325865887 0.9691768309482806 0.9897803910323091 1.0198841652852877 1.0 18.217758300780083 -5.251376295296961 24.999077034811492 1.0172245350094564 0.9193326894657997 0.36721893260654337 0.052423910324794355 716.1372404827734 1779044.9077318602 0.012784926114330207 0.03296539576280152 5.6056206546392625e-06 5.251376295296961 -0.09789184554365671 GPPS(ph)PPAPVMHS(ph)PSRK ddPTM_PC-9_Lapatinib_30min_R1 1 GPPSPPAPVMHSPSRK 16 1 G3V3A4;Q13573;G3V4X8 G3V3A4 SNW1 SNW domain-containing protein 1 2 GPPS(1)PPAPVMHS(0.5)PS(0.5)RK 46.415 0.037763 13400000.0 77635.0 57724.0 73162.0 59692.0 67965.0 67734.0 60039.0 62337.0 73937.0 52094.0 True False 76527.91066348477 57590.34362455199 67146.90277348715 64081.94880667461 63967.43232433121 64837.174715665926 63147.52564691683 65233.40459240685 65609.43646887351 61098.37848910826 1.2525358701152285 0.9425838303518704 1.0989964780400372 1.0488322340354452 1.046957937447299 1.0611930515835892 1.0335384867566306 1.0676781643891862 1.0738326955856843 1.0 15.89884647192137 -4.742257426139317 24.999993803911437 1.0461886003640342 1.2525365578612369 0.6977597150459736 0.04156291554586742 722.1769177640712 941170.2180533009 0.009606079950554004 0.35209135314393497 1.8102667469079076e-05 4.742257426139317 0.2063479574972027 GPPS(ph)PPAPVMHSPS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 GPPSPPAPVMHSPSR 15 0 G3V3A4;Q13573;G3V4X8 G3V3A4 SNW1 SNW domain-containing protein 1 2 GPPS(1)PPAPVMHS(0.468)PS(0.532)R;GPPS(1)PPAPVMHS(0.215)PS(0.786)R 101.54 0.018867 64940000.0 113041.0 113812.0 169686.0 234378.0 204443.0 167499.0 155265.0 205155.0 136854.0 161308.0 True False 148985.68660113457 150599.5032850364 167435.8527691373 180345.7732040031 176059.6183930568 157025.2610512594 169083.2842118398 173453.00874290566 144087.82304702175 155660.6560183337 0.9571184550551235 0.9674859861010657 1.075646583099436 1.1585828931799054 1.1310476448995594 1.0087665378511894 1.086230063118359 1.1143021825789836 0.9256534485506157 1.0 17.248044816798597 -5.250387829827929 7.6656735160025 1.0714640519638337 0.9617992192576129 0.26167823298168347 0.0659990184565373 0.1865969211796876 77.39488560027385 0.017058046756038562 0.04196159852630418 5.618393722578968e-06 5.250387829827929 -0.10966483270622074 GPPS(ph)PPAPVMHSPS(ph)RK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPPSPPAPVMHSPSRK 16 1 G3V3A4;Q13573;G3V4X8 G3V3A4 SNW1 SNW domain-containing protein 1 2 GPPS(1)PPAPVMHS(0.308)PS(0.692)RK 47.32 0.039332 22308000.0 73238.0 70047.0 92315.0 83357.0 94223.0 114950.0 108910.0 94583.0 99254.0 64054.0 True False 85635.74688356437 77000.80323550422 94516.13970658688 78686.77753704034 75760.67953546504 108921.81964209021 98593.25635988245 92100.29646897205 100705.40197988025 75666.48314881501 1.1317527037055837 1.0176342289368066 1.249115008037308 1.0399158816762404 1.001244889186468 1.439498905055111 1.302997737663806 1.217187486933102 1.3309116241311312 1.0 16.207366772192874 -6.746210392826358 24.99959400776137 1.2744983197983855 1.0903140756166447 0.3177288486096068 0.12350886495368893 267.10537694351797 438473.8983464921 0.03927037722935094 0.03912648840809474 1.7938643833874374e-07 6.746210392826358 -0.18418424418174073 GPPS(ph)PPAPVMHSPSR ddPTM_PC-9_AZD4547_30min_R2 1 GPPSPPAPVMHSPSR 15 0 G3V3A4;Q13573;G3V4X8 G3V3A4 SNW1 SNW domain-containing protein 1 1 GPPS(1)PPAPVMHSPSR 76.068 0.008119 8976600.0 23775.0 19223.0 25796.0 43403.0 42373.0 32639.0 29265.0 39410.0 21278.0 26374.0 True False 31334.95544927924 25436.45882374664 25453.92818519302 33397.10891966543 36490.24036122036 30598.078170329707 31869.528306182885 33320.090051706866 22402.71164010205 25450.654287620822 1.2312043177813523 0.9994422357981938 1.0001286370690199 1.3122298759882867 1.4337643326902283 1.202251141543838 1.252208605170681 1.3092036721395304 0.8802410887722723 1.0 14.635415125256014 -8.265951304711498 24.931894228361276 0.9401205177144574 1.2140441106153983 0.42300565848770744 0.12955607131013483 424.22520681327285 2344127.9810888916 0.12398170451340876 0.03618853347933148 5.420616656832209e-09 8.265951304711498 0.2739235929009409 GPPS(ph)PPAPVMHSPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GPPSPPAPVMHSPSR 15 0 G3V3A4;Q13573;G3V4X8 G3V3A4 SNW1 SNW domain-containing protein 1 1 GPPS(0.998)PPAPVMHS(0.002)PSR;GPPS(1)PPAPVMHSPSR 79.804 0.0092434 17456600.0 80540.0 74767.0 84987.0 103809.0 98068.0 97827.0 99039.0 94863.0 77718.0 68770.0 True False 94173.83126249044 82189.37364211101 87013.41239499245 97992.91828331877 78852.27938702857 92696.77990540888 89657.30893973343 92372.94676565661 78854.47872198923 81237.45661697965 1.1592415024328435 1.011717710829125 1.0710996628715916 1.206252908006933 0.9706394398682769 1.141059601883623 1.1036449523826417 1.1370733478422257 0.970666512785774 1.0 16.30985745198128 -8.269572135876158 24.87230697543153 0.9853332361896231 1.0968867220858138 0.32421640578962563 0.06614249953215971 732.8696949135416 2241295.040501007 0.05719219245763808 0.015810647883959385 5.375611373428409e-09 8.269572135876158 0.11155348589619074 GPPS(ph)PPAPVMHSPSR ddPTM_PC-9_Lapatinib_30min_R1 5 GPPSPPAPVMHSPSR 15 0 G3V3A4;Q13573;G3V4X8 G3V3A4 SNW1 SNW domain-containing protein 1 1 GPPS(1)PPAPVMHSPSR;GPPS(1)PPAPVMHSPSR;GPPS(1)PPAPVMHSPSR;GPPS(1)PPAPVMHSPSR;GPPS(1)PPAPVMHSPSR 107.15 0.00049211 102110000.0 300318.0 294666.0 350773.0 336477.0 335837.0 333358.0 384427.0 333921.0 371195.0 267678.0 True False 296035.4102484243 293983.71898122446 321933.7979629374 361222.64103436825 316083.72794094635 319101.05543545284 404330.7490442423 349436.18869854254 329387.11024336296 313945.7856414846 0.9429507379547584 0.9364155609877938 1.0254439227624315 1.1505892340497037 1.0068099092175844 1.0164208918537783 1.2878999099098412 1.1130462795814904 1.0491846850892652 1.0 18.260155920371787 -5.460342629811193 3.4800498682662973 1.0957436831879355 0.9409765387848665 0.34494566076951383 0.08136496496495366 0.26445238576935237 6.251191611414388 0.023052437645634156 0.05083096338838225 3.464634057387768e-06 5.460342629811193 -0.15476714440306893 GPPS(ph)PPAPVMHSPSRK ddPTM_PC-9_AZD4547_30min_R2 1 GPPSPPAPVMHSPSRK 16 1 G3V3A4;Q13573;G3V4X8 G3V3A4 SNW1 SNW domain-containing protein 1 1 GPPS(1)PPAPVMHSPSRK 55.18899999999999 0.023023 8282500.0 32276.0 25345.0 49072.0 73420.0 60285.0 45855.0 33541.0 44799.0 39471.0 43683.0 True False 42539.09661749471 33537.27560151163 48421.27321692479 56494.15332769245 51915.46834484624 42987.67960110505 36526.08402247327 37876.34392860731 41557.35647835641 42153.67146607037 1.0091433352782704 0.7955956014058204 1.1486845992975778 1.3401953225631789 1.2315764330666468 1.0197849465071143 0.8664982847786635 0.8985301306220528 0.9858537829096585 1.0 15.363370670864313 -7.000548792269429 24.979432920479155 0.9312471267613601 1.1055711480457315 0.24537114139663385 0.1382531830515131 31.94068655373707 1453928.4831127918 0.05618819995224161 0.04899612222754078 9.987371571592347e-08 7.000548792269429 0.1743240212843714 GPPS(ph)PPAPVMHSPSRK ddPTM_PC-9_Lapatinib_30min_R1 2 GPPSPPAPVMHSPSRK 16 1 G3V3A4;Q13573;G3V4X8 G3V3A4 SNW1 SNW domain-containing protein 1 1 GPPS(1)PPAPVMHSPSRK;GPPS(1)PPAPVMHSPSRK 102.5 0.00068407 19775600.0 92069.0 51079.0 74509.0 51269.0 56833.0 61479.0 48235.0 48712.0 67017.0 44389.0 True False 90756.07917661333 50960.72971378441 68383.15763305733 55039.493288370366 53490.19467797705 58849.68648454873 50732.37228433237 50975.33735189892 59468.83973970398 52061.57950537538 1.7432448273537826 0.9788548522336455 1.3135052428825509 1.0571998354888084 1.0274408726391824 1.1303861128238046 0.9744685575491275 0.9791354360778795 1.1422788225924607 1.0 15.667931462132891 -4.7566094297689885 24.99999999968881 1.0716232705704292 1.7432458488556888 0.8031178563186583 0.10041976876728144 63.23101179533821 327247.724994546 0.024854326759184656 0.19815689488999003 1.7514210706654092e-05 4.7566094297689885 0.6716225782852596 GPPVT(ph)PSSEKR ddPTM_PC-9_AZD4547_30min_R2 1 GPPVTPSSEKR 11 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 GPPVT(0.985)PS(0.007)S(0.007)EKR 63.662 0.042338 10671000.0 17508.0 14316.0 27061.0 35787.0 32726.0 32550.0 34135.0 38983.0 32564.0 30532.0 True False 23075.179810977108 18943.36703536163 26702.1534586567 27536.860053638375 28182.559791879234 30514.64335439908 37172.94887174282 32959.07309022297 34285.26655927638 29463.08397321754 0.7831895612812579 0.6429526200509588 0.9062918696131547 0.9346224610658498 0.9565380127042259 1.035690743784236 1.261678814937828 1.1186565914207536 1.1636686298841725 1.0 14.846620828253252 -5.996851962217309 0.8042332000471532 1.1427291807494206 0.6931937187524072 0.7595139051840041 0.08439632080802625 0.3484809408796225 0.4491432154565487 0.042196836673845745 0.10261748951109981 1.0072749597439486e-06 5.996851962217309 -0.44953546199701344 GPPVT(ph)PSSEKR ddPTM_PC-9_Lapatinib_30min_R1 1 GPPVTPSSEKR 11 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 GPPVT(0.989)PS(0.006)S(0.004)EKR 77.078 0.016896 9700500.0 65715.0 56099.0 62834.0 47705.0 49657.0 38419.0 29537.0 30750.0 51565.0 32689.0 True False 64777.89204934501 55969.10621221231 57668.031066254116 51213.384839214865 46736.272889418266 36775.90892906321 31066.281334349034 32178.757258394056 45757.2066964776 38339.250094645424 1.689597263624937 1.4598383138440447 1.5041512529299108 1.3357951632540535 1.219018962917733 0.9592234808525754 0.8102996604695678 0.8393162928058481 1.1934820473410406 1.0 15.226534498106979 -6.273540930538307 1.2619270166722343 0.9350654522805891 1.5638287185679172 0.8318580245830534 0.11587083543546804 0.1747147410554667 0.5680094700468862 0.04771291339012545 0.06781159418874838 5.326710198190527e-07 6.273540930538307 0.628763266287328 GPQPPTVS(ph)PIR ddPTM_PC-9_AZD4547_30min_R2 2 GPQPPTVSPIR 11 0 P46087-2;P46087;P46087-4 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 GPQPPT(0.021)VS(0.979)PIR;GPQPPT(0.021)VS(0.979)PIR 161.87 0.0013210999999999997 865420000.0 557530.0 610130.0 675570.0 808420.0 651130.0 609110.0 526910.0 671850.0 556990.0 569083.0 True False 734812.9426555911 807342.5907575585 666611.5003904033 622051.258964494 560731.8388219238 571022.2554100784 573803.969240076 568031.0200771188 586431.3542823788 549159.5773853838 1.3380681552603084 1.4701420570709443 1.2138757618763978 1.1327331518575283 1.0210726752534063 1.0398111567657358 1.0448765584168216 1.0343642239321114 1.0678705761164187 1.0 19.066865909732613 -5.615228983103812 1.8355650514974555 1.0391691507840544 1.4088337312897923 0.917831092402144 0.042785845977640465 0.08174338275706376 0.5487198460790077 0.01195410846879297 0.029108192690985378 2.4253309946669142e-06 5.615228983103812 0.3696645805057379 GPQPPTVS(ph)PIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GPQPPTVSPIR 11 0 P46087-2;P46087;P46087-4 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 GPQPPT(0.231)VS(0.769)PIR;GPQPPT(0.112)VS(0.888)PIR;GPQPPT(0.002)VS(0.998)PIR;GPQPPT(0.002)VS(0.998)PIR;GPQPPT(0.366)VS(0.634)PIR 98.25299999999999 0.0050528 785549000.0 243297.0 283594.0 298675.0 252467.0 313461.0 275810.0 291654.0 324320.0 279326.0 192510.0 True False 284482.37676521036 311747.3381125469 305796.5447312448 238322.09249905768 252040.56724861596 261346.03806424452 264026.42172789545 315806.94364544464 283410.61431712547 227410.53909167903 1.2509639082756987 1.3708570383664938 1.3446894148030886 1.0479817402085296 1.1083064498915218 1.1492257091870515 1.161012250278581 1.3887084780979706 1.2462510112729224 1.0 17.79493959033352 -5.732713906570828 24.99819836129205 1.1713212105783084 1.3270389455719518 0.33574051406037886 0.1048902483619536 277.15114826949304 241187.39068870747 0.030284698531296436 0.05244326917920108 1.8504872342782795e-06 5.732713906570828 0.1557177349936434 GPQPPTVS(ph)PIR ddPTM_PC-9_Lapatinib_30min_R1 3 GPQPPTVSPIR 11 0 P46087-2;P46087;P46087-4 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 GPQPPT(0.005)VS(0.995)PIR;GPQPPT(0.001)VS(0.999)PIR;GPQPPT(0.217)VS(0.783)PIR 99.161 0.0046767 913546000.0 116169.0 116210.0 203720.0 129642.0 175237.0 191956.0 154493.0 159617.0 191178.0 145345.0 True False 114512.40875721426 115940.92288492098 186970.9279819416 139176.3051530341 164929.90418919767 183746.48935129124 162491.89159994552 167033.3885305067 169645.52044641113 170467.68958996155 0.6717543308802939 0.6801343008977372 1.0968115332100559 0.8164380328483661 0.9675141640384503 1.0778962851744525 0.9532122597003526 0.9798536539814927 0.9951769796051789 1.0 17.37913879148296 -5.24664310101735 24.54863354686372 0.9805579655039924 0.6759442202373149 0.7488328908737374 0.07174276751793311 299.07623400101807 496197.292198955 0.017980203442509033 0.04711176051731502 5.66704810234726e-06 5.24664310101735 -0.3046137452666775 GPRIS(ph)APNVDFNLEGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPRISAPNVDFNLEGPK 17 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GPRIS(1)APNVDFNLEGPK 86.772 0.0014196 3224500.0 18268.0 7181.8 16928.0 27286.0 32288.0 35282.0 29926.0 38234.0 35241.0 29964.0 True False 21360.411590553416 7894.761641137308 17331.627719797507 25757.253882405577 25961.398181347373 33431.74980958872 27091.192634522416 37230.39801227158 35756.332955578124 35396.23600510651 0.6034656223749839 0.22303958081865977 0.48964606624549356 0.7276834146627809 0.7334508160020743 0.9445001385109315 0.7653693073640386 1.051817995758093 1.0101733119425371 1.0 15.111308333488166 -6.1637069610409725 0.8478604095385528 0.9809867518124179 0.3707316282063309 0.7735505972588671 0.11914030771258435 0.29756905861109373 0.45034584666011007 0.059607225844348105 0.11256051027015541 6.859509137530004e-07 6.1637069610409725 -0.610255123606087 GPS(ph)LDIDTPDVNIEGPEGK ddPTM_PC-9_AZD4547_30min_R2 2 GPSLDIDTPDVNIEGPEGK 19 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GPS(0.734)LDIDT(0.266)PDVNIEGPEGK;GPS(0.97)LDIDT(0.03)PDVNIEGPEGK 176.17 1.1656e-36 0.0 25142.1 28348.0 34667.0 39981.0 32877.0 38282.0 44400.0 71606.0 58662.0 45400.0 True False 33136.76481183273 37510.93662464599 34207.29292898458 30763.998150292427 28312.59604832896 35888.22048826745 48351.51398580285 60540.93804218522 61762.753559153425 43810.55981868451 0.7563647885115684 0.8562076535860236 0.7808001785541144 0.7022050911381431 0.6462504968095406 0.8191682698599457 1.1036497635709666 1.3818800374325613 1.4097686451569285 1.0 15.418991029327405 -7.36960691570116 2.712669577627107 1.2929983190760264 0.752578131746273 0.7949628958209941 0.11716573045417705 0.11539088929171547 1.6477029310877012 0.056310360003902125 0.03496628756705117 4.2696579499467936e-08 7.36960691570116 -0.5404201873297534 GPS(ph)PAPASS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 GPSPAPASSPK 11 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 2 GPS(1)PAPAS(0.232)S(0.768)PK 108.32 0.0098081 0.0 37578.0 49391.0 37811.0 40581.0 45338.0 37351.0 46390.0 46285.0 40844.0 38193.0 True False 37042.1308290388 49276.638174073974 34702.32553468082 43565.46211424751 42671.30797793754 35753.584799433644 48791.84721198671 48435.5700716998 36243.71861361252 44794.60916102645 0.8269327832704321 1.100057330491168 0.7746987011301704 0.972560380148414 0.9525991805072767 0.7981671337036924 1.0892348013706536 1.0812812295690521 0.8091089372679775 1.0 15.45103750012208 -7.272205535779058 24.992375529430735 1.0016796666906769 0.9124982751528278 0.1277121264568012 0.11439595859984349 1595.9479151653438 3704792.7850350174 0.045904470566709814 0.031307743218203135 5.3431142938862684e-08 7.272205535779058 -0.0891813915378491 GPS(ph)PAPASS(ph)PKR ddPTM_PC-9_Lapatinib_30min_R1 1 GPSPAPASSPKR 12 1 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 2 GPS(0.894)PAPAS(0.119)S(0.987)PKR 101.45 0.015677 8594500.0 17240.0 20732.0 21969.0 19574.0 23157.0 24399.0 23003.0 19430.0 21458.0 20356.0 True False 16994.154438571204 20683.996327770277 20162.793622792404 21013.537256949847 21794.95078841369 23355.511646846968 24193.982785456585 20332.78873270232 19041.17407724262 23874.50747733495 0.7118117286693537 0.8663632683273756 0.8445323381826314 0.8801663145050787 0.9128963522746817 0.9782615062957555 1.0133814407867858 0.8516526990977749 0.7975525398929878 1.0 14.543183350715191 -3.75512183330666 0.7455911145823854 0.9210295972753567 1.0560858137739044e-15 0.4708461904986805 0.06503884927820591 10.802764585440718 1.4494387736253873 0.02649275087687305 11.877666846478506 0.00017574305300784146 3.75512183330666 -0.9210295972753556 GPS(ph)PEGSSSTESSPEHPPK ddPTM_PC-9_AZD4547_30min_R2 2 GPSPEGSSSTESSPEHPPK 19 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 GPS(0.86)PEGS(0.046)S(0.046)S(0.046)T(0.002)ESSPEHPPK;GPS(0.918)PEGS(0.032)S(0.032)S(0.007)T(0.009)ES(0.002)S(0.002)PEHPPK 137.73 7.0023e-05 7183100.0 24476.2 19864.4 72171.0 103364.0 85259.0 87819.0 51495.0 89561.0 63382.0 79819.0 True False 32259.12246341318 26285.178830486006 71213.96538430623 79535.0267578806 73422.25952746528 82327.66404731097 56077.95524096663 75721.40535703911 66732.24312308255 77024.56110501268 0.4188160503690788 0.3412571062190109 0.9245617808482611 1.0325930536552521 0.9532317805402859 1.0688495054852467 0.7280529020413611 0.9830812960271609 0.8663761554201143 1.0 16.233030936191867 -5.265212234210717 23.903777128532976 0.9441446018466914 0.3800365184625459 0.8582467377654149 0.09177562343480768 52.00381142010955 329486.97976890736 0.023537621136514336 0.05228107945975351 5.429849167961943e-06 5.265212234210717 -0.5641080833841454 GPS(ph)PEGSSSTESSPEHPPK ddPTM_PC-9_Lapatinib_30min_R1 1 GPSPEGSSSTESSPEHPPK 19 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 GPS(0.906)PEGS(0.034)S(0.034)S(0.011)T(0.012)ES(0.002)S(0.002)PEHPPK 59.339 0.012572 3665900.0 15489.0 11753.0 28460.0 15779.0 24637.0 27539.0 17364.0 22118.0 33572.0 18216.0 True False 15268.124019665283 11725.786650602162 26120.12865877697 16939.44029720095 23187.900098205653 26361.22116654448 18263.022957295485 23145.68302572878 29790.767831167355 21364.61132870572 0.7146455315641932 0.5488415618798208 1.2225885253377713 0.7928737872446542 1.0853415370608752 1.2338731915579135 0.8548258929829953 1.0833655089540521 1.3943978372843209 1.0 14.382935450874616 -5.256173251040909 24.992285703180027 1.0732885291814818 0.6317435113032628 0.5230294011445344 0.17231106348083833 333.4410955251763 1582450.65441322 0.04368213252581537 0.10859228110987966 5.544045028749472e-06 5.256173251040909 -0.441545017878219 GPS(ph)PRPPATAYDAPASAFGSSLLGSGGSAFAPPLR ddPTM_PC-9_AZD4547_30min_R2 2 GPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLR 35 1 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 GPS(0.969)PRPPAT(0.02)AY(0.007)DAPAS(0.004)AFGSSLLGSGGSAFAPPLR;GPS(0.834)PRPPAT(0.082)AY(0.075)DAPAS(0.009)AFGSSLLGSGGSAFAPPLR 61.099 0.00012513 9784600.0 13974.599999999999 17793.300000000003 19620.4 25370.0 22524.0 22746.0 21988.0 28039.0 22615.3 27927.0 True False 18418.23211026276 23544.636258053957 19360.22067625838 19521.338462592717 19396.93139254071 21323.689024244588 23944.88940359985 23706.216822121503 23810.698587949984 26949.284230317237 0.6834404933672685 0.8736646234027566 0.7183946152632373 0.7243731705731807 0.7197568301543116 0.791252518694207 0.8885167115741975 0.8796603508842967 0.8835373282813788 1.0 14.717959335232797 -7.227085301905075 2.3102742671909935 0.9099614580109183 0.7482569102857923 0.6673137553330204 0.05663787077301026 0.2043928222870161 2.1389785973204782 0.026460810606977116 0.017809501779480857 5.9280887665104035e-08 7.227085301905075 -0.161704547725126 GPS(ph)PRPPATAYDAPASAFGSSLLGSGGSAFAPPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLR 35 1 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 GPS(0.856)PRPPAT(0.06)AY(0.055)DAPAS(0.025)AFGS(0.002)S(0.001)LLGSGGSAFAPPLR 53.77 0.0005993 3237400.0 5366.4 5751.6 5826.5 5485.2 6814.2 3616.6 5277.1 4117.9 3689.9 3241.1 True False 6274.825528768655 6322.580836999821 5965.425857124296 5177.882027258335 5479.006426143989 3426.939129339566 4777.214885104532 4009.809488275703 3743.857806895032 3828.6857734665173 1.6388980188069566 1.651371047688595 1.558087085251491 1.3523914819915468 1.4310410282594856 0.8950693089228874 1.247742741964225 1.0473070200914387 0.9778441032796793 1.0 11.902633545355787 -6.2313088155688465 0.8405859687534553 1.023096437981908 1.6804533364382248 0.8241474867921461 0.11447247810669403 0.2549463013181539 0.3849327003990127 0.05786144747100777 0.10064765904844106 5.870717525421661e-07 6.2313088155688465 0.6573568984563167 GPS(ph)PS(ph)PVGSPASVAQSR ddPTM_PC-9_AZD4547_30min_R2 1 GPSPSPVGSPASVAQSR 17 0 O14497-2;O14497;H0Y488;A0A1B0GTU5;O14497-3;A0A087WUV6 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 2 GPS(0.99)PS(0.536)PVGS(0.474)PASVAQSR 99.915 0.014669999999999999 3882400.0 8287.3 7762.1 13212.0 15342.0 16326.0 16460.0 12939.0 17096.0 14820.0 13416.0 True False 10922.48901345159 10271.047028861452 13036.800247432559 11805.138931537147 14059.416707273118 15430.753597954188 14090.545933835661 14454.206026997723 15603.354944370349 12946.30992351259 0.8436758487926035 0.7933571102146699 1.0069896614907714 0.911853570730383 1.085978691251547 1.1919036149389137 1.0883831776840869 1.1164730423104232 1.2052357031892258 1.0 13.660253325826112 -5.860758137631021 1.0235618935043416 1.130081365803437 0.81418908851858 0.7124266367362624 0.07129002935065037 0.3045473286030762 0.6266292004012046 0.027709305127443306 0.07091149762593234 1.3779766624172834e-06 5.860758137631021 -0.315892277284857 GPS(ph)PSASQR ddPTM_PC-9_AZD4547_30min_R2 1 GPSPSASQR 9 0 Q8IY92;Q8IY92-2 Q8IY92 SLX4 Structure-specific endonuclease subunit SLX4 1 GPS(0.903)PS(0.096)AS(0.001)QR 70.41199999999999 0.037743 3627000.0 10648.0 9809.9 10674.0 15380.0 12603.0 9719.1 9158.3 9400.1 10851.0 9320.0 True False 14033.84250784122 12980.758331949852 10532.455785732294 11834.378618631288 10853.290993615286 9111.363140575731 9973.370958022031 7947.530537808919 11424.561707244447 8993.709636787222 1.560406447906457 1.4433152565715812 1.1710913750929979 1.3158506441240663 1.206764664629795 1.0130817547530409 1.1089273904538426 0.8836765760483207 1.2702835835964998 1.0 13.134700591803409 -2.3443830544129645 0.34727705226675903 1.021890455340066 4.674381397400008 0.6898078061557096 0.11020839236573272 18.61359537391685 0.44838015934246717 0.09228942500436582 40.22644787813981 0.004524982933863941 2.3443830544129645 3.6524909420599423 GPS(ph)PSPVGSPASVAQSR ddPTM_PC-9_AZD4547_30min_R2 6 GPSPSPVGSPASVAQSR 17 0 O14497-2;O14497;H0Y488;A0A1B0GTU5;O14497-3;A0A087WUV6 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 GPS(0.956)PS(0.044)PVGSPASVAQSR;GPS(0.634)PS(0.272)PVGS(0.094)PASVAQSR;GPS(1)PSPVGSPASVAQSR;GPS(0.921)PS(0.079)PVGSPASVAQSR;GPS(0.556)PS(0.441)PVGS(0.001)PAS(0.002)VAQSR;GPS(0.5)PS(0.5)PVGSPASVAQSR 237.34 1.9449e-37 244208600.0 81671.5 88475.8 113955.6 140198.8 130082.0 124599.5 103813.8 133546.9 105399.7 105904.3 True False 107641.33812726843 117073.87211143124 112444.47428673366 107878.13270986779 112022.35967876429 116808.2735679401 113053.02708602093 112910.29520746726 110970.91296424765 102196.62269175991 1.0532768626995688 1.1455747658564344 1.1002758342208898 1.0555939117014086 1.096145417805442 1.1429758683929416 1.1062305593699073 1.1048339194928327 1.0858569494899288 1.0 16.640987994524885 -8.792379287807181 2.6447144117605017 1.0000078516973903 1.1019663732858263 0.5237539686170214 0.02858973923591709 1.3461976303639014 12.211717670681187 0.02767427346537042 0.007427685289779777 1.6129492844463177e-09 8.792379287807181 0.10195852158843599 GPS(ph)PSPVGSPASVAQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 GPSPSPVGSPASVAQSR 17 0 O14497-2;O14497;H0Y488;A0A1B0GTU5;O14497-3;A0A087WUV6 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 GPS(0.98)PS(0.019)PVGS(0.001)PASVAQSR;GPS(0.979)PS(0.019)PVGS(0.002)PASVAQSR;GPS(0.996)PS(0.004)PVGSPASVAQSR;GPS(0.983)PS(0.017)PVGSPASVAQSR;GPS(0.648)PS(0.352)PVGSPASVAQSR;GPS(0.954)PS(0.046)PVGSPASVAQSR 224.36 6.6963e-29 214583800.0 73318.4 98430.90000000001 79701.8 78235.40000000001 97739.3 82060.0 92553.0 77530.7 67025.9 47341.2 True False 85729.75701559187 108202.46924484443 81602.19318275986 73852.12418058905 78587.98579243555 77756.62914162618 83785.7098143069 75495.6012755671 68006.02698695495 55923.784807266995 1.5329748748416567 1.934820213219619 1.4591679276356149 1.3205852292563782 1.4052694406016573 1.3904035538653694 1.4982124350678676 1.3499730308982387 1.2160483633453567 1.0 15.77117438221378 -1.5228787457808741 0.071651239683248 0.5460217737610283 3.5243275633178452 0.6273286347556656 0.1390037875264673 164.34282909445378 0.8711309175761681 6.1794239154068915 49.19161512400491 0.02999999996542416 1.5228787457808741 2.978305789556817 GPS(ph)PSPVGSPASVAQSR ddPTM_PC-9_Lapatinib_30min_R1 4 GPSPSPVGSPASVAQSR 17 0 O14497-2;O14497;H0Y488;A0A1B0GTU5;O14497-3;A0A087WUV6 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 GPS(0.997)PS(0.003)PVGSPASVAQSR;GPS(0.967)PS(0.033)PVGSPASVAQSR;GPS(0.986)PS(0.014)PVGSPASVAQSR;GPS(0.86)PS(0.136)PVGS(0.004)PAS(0.001)VAQSR 242.1 2.1218000000000001e-38 133694800.0 95970.3 103290.8 143774.9 102436.9 110224.1 124795.6 85592.90000000001 108642.4 119293.8 85262.8 True False 94601.74592320248 103051.63649876775 131954.28270916364 109970.45134548076 103740.93514691829 119458.38310075221 90024.48155272391 113690.32252258043 105857.67602459542 100000.36137446036 0.9460140405788907 1.0305126409781822 1.3195380586180978 1.0997005394179176 1.037405602550285 1.1945795141022493 0.9002415622841514 1.1368991167627562 1.0585729348337234 1.0 16.60964568795881 -7.233490015679224 24.99813140460385 1.0353365644943997 1.1077458034535483 0.11153294665322622 0.10949195408402304 1943.1055596496526 1737931.4520398257 0.04294186387276356 0.033254544285675126 5.8413063595469316e-08 7.233490015679224 0.07240923895914864 GPS(ph)PSSPTPPAAAAPAEQAPR ddPTM_PC-9_AZD4547_30min_R2 1 GPSPSSPTPPAAAAPAEQAPR 21 0 Q86VQ1 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 GPS(0.881)PS(0.037)S(0.08)PT(0.002)PPAAAAPAEQAPR 180.03 6.6429e-13 14668000.0 29951.0 27862.0 40549.0 57244.0 53850.0 47749.0 38004.0 50577.0 41646.0 48523.0 True False 39474.794980498926 36867.84662889394 40011.293765754046 44047.280210983714 46373.85701866089 44763.24748169592 41386.28237649665 42761.48679383855 43847.32253800591 46824.22453925173 0.8430421511285908 0.7873669450305242 0.854499869660702 0.9406942804586083 0.9903817409680047 0.9559848117542633 0.8838647683701293 0.9132342759460442 0.9364238910406226 1.0 15.514967481596205 -5.654110240395821 3.5554215201562203 0.9421858561906334 0.8160371041834084 0.7165467342644378 0.034342763343359284 0.129155981283535 3.1353330853196466 0.010173798457654587 0.018673612055397817 2.2176334289540635e-06 5.654110240395821 -0.12614875200722508 GPS(ph)PTPEDVSMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPSPTPEDVSMK 12 0 H1UBN3;O95067 H1UBN3 CCNB2V;CCNB2 G2/mitotic-specific cyclin-B2 1 GPS(0.867)PT(0.133)PEDVSMK 77.593 0.015318 4019100.0 30533.0 37459.0 32317.0 26208.0 33359.0 21813.0 31334.0 26243.0 27139.0 21992.0 True False 35701.63384576131 41177.68196209341 33087.55984290499 24739.65072748241 26822.543419585207 20669.087880408115 28365.816681485165 25554.149056756916 27535.85653305624 25978.975511423803 1.3742510296474983 1.5850387150173124 1.2736283549116598 0.9522950863325453 1.032471176848004 0.7956082745187254 1.091875877438346 0.9836472976203362 1.0599284995263891 1.0 14.665056918351752 -5.5834881587294936 3.4350242069292984 0.9855507056669842 1.4760931033208222 0.8313567106482582 0.0902196858020233 0.0816395889291739 1.9482508819688265 0.02434519667477696 0.04727202940934353 2.6092268640053177e-06 5.5834881587294936 0.490542397653838 GPS(ph)PTPEDVSMKEENLCQAFSDALLCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPSPTPEDVSMKEENLCQAFSDALLCK 27 1 H1UBN3;O95067 H1UBN3 CCNB2V;CCNB2 G2/mitotic-specific cyclin-B2 1 GPS(0.472)PT(0.267)PEDVS(0.249)MKEENLCQAFS(0.013)DALLCK 58.137 0.0043948 2556300.0 8485.1 5315.3 8402.5 10095.0 11752.0 7542.8 9427.2 10013.0 8394.1 6037.6 True False 9921.459841635904 5842.967856406073 8602.8474666587 9529.409878431588 9449.279962437882 7147.242289659486 8534.187368982479 9750.169359650463 8516.847832422985 7132.169086384695 1.391085898478762 0.8192413535961022 1.2062035213216593 1.3361166516120915 1.3248816521297215 1.002113410814049 1.1965767027697416 1.3670692942857352 1.1941455298194823 1.0 12.80012519082144 -5.483493538110671 24.999032636736782 1.2190644097525036 1.08205333597748 0.03926025754398221 0.17537355097960358 1243.2740845157464 789142.8975724998 0.044054319071921706 0.09168330137706608 3.284781317092671e-06 5.483493538110671 -0.13701107377502364 GPS(ph)PWGFR ddPTM_PC-9_AZD4547_30min_R2 2 GPSPWGFR 8 0 P50479;P50479-2 P50479 PDLIM4 PDZ and LIM domain protein 4 1 GPS(1)PWGFR;GPS(1)PWGFR 85.86200000000001 0.012908000000000001 5512600.0 24164.0 22280.0 34666.0 41077.0 34224.0 26755.0 26612.0 33285.0 24767.0 28038.0 True False 31847.64935757658 29481.574290853383 34206.30618963797 31607.33228332363 29472.58834924142 25082.005620489937 28980.416445724884 28141.568063208873 26076.133057167383 27056.398154102993 1.1770838518927922 1.089634108832133 1.2642594182275044 1.1682017725825973 1.0893019899166447 0.9270267785694288 1.0711113977796827 1.040107700327485 0.9637695641765621 1.0 14.72368217484772 -6.470248091538619 3.719978997052372 1.0068430052765778 1.1737190399782949 0.6947909646331518 0.05421612964874782 0.14017956097469964 3.9239971628043406 0.017950018306877896 0.019770299624187925 3.3865064605524353e-07 6.470248091538619 0.16687603470171708 GPS(ph)PWGFR ddPTM_PC-9_Lapatinib_30min_R1 1 GPSPWGFR 8 0 P50479;P50479-2 P50479 PDLIM4 PDZ and LIM domain protein 4 1 GPS(1)PWGFR 101.46 0.0045792 3208700.0 20463.0 11304.0 19241.0 17996.0 17242.0 20625.0 15611.0 15091.0 16797.0 14593.0 True False 20171.193867545386 11277.826282515696 17659.07925240787 19319.485872896144 16227.859459076262 19742.91682922328 16419.26119479035 15792.182952404064 14905.14497974854 17115.38060604976 1.1785419402484973 0.6589293304134488 1.0317666699252912 1.128779214297303 0.948144819714977 1.1535190063050522 0.9593278450954603 0.9226895571823869 0.8708626073135664 1.0 14.06300575441868 GPS(ph)SPPTTTAPMR ddPTM_PC-9_Lapatinib_30min_R1 1 GPSSPPTTTAPMR 13 0 Q9NXL9-4;Q9NXL9 Q9NXL9-4 MCM9 DNA helicase MCM9 1 GPS(0.811)S(0.184)PPT(0.001)T(0.002)T(0.002)APMR 90.79299999999999 0.0054342 3709800.0 20601.0 20870.0 25151.0 15774.0 22339.0 20019.0 18194.0 18049.0 24315.0 14615.0 True False 20307.22596223929 20821.676797248983 23083.1818656676 16934.072580521442 21025.063940163822 19162.834036568274 19135.996296074292 18887.62243111397 21576.388651698875 17141.18327673661 1.184703858210274 1.2147164207448504 1.3466504320617851 0.9879173629456345 1.2265818293126982 1.117941143688451 1.1163754559491217 1.1018855656684776 1.2587455780244508 1.0 14.065179083431408 -14.522878745229853 0.08751421742631901 0.5148968081344103 1.3013285214700585 0.2233794758885742 0.09437734202926461 342.1823500382852 2.0830889971181596 32.16019996541112 2.4057510622228304 3.0000000003487328e-15 14.522878745229853 0.7864317133356482 GPS(ph)STGASGQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPSSTGASGQAK 12 0 Q9NWH9;H7BXE3 Q9NWH9 SLTM SAFB-like transcription modulator 1 GPS(0.563)S(0.425)T(0.012)GASGQAK 86.772 0.031932999999999996 0.0 10508.0 14833.0 11600.0 8560.2 19746.0 18196.0 11408.0 11826.0 14729.0 17164.0 True False 12286.796857539708 16305.522212118081 11876.587993244975 8080.599746542846 15876.913047847036 17241.769727772717 10327.351653232368 11515.580030682742 14944.38376046963 20275.697329850755 0.605986401239604 0.8041904525824811 0.5857548472949313 0.3985362187591072 0.7830513934764829 0.8503663004669457 0.509346311755601 0.5679498881515167 0.7370589290888587 1.0 14.307463912587183 -8.60234420104854 5.540849310176716 0.999986758529846 0.6419359306517329 0.40347856450733754 0.1328359436096492 0.7504541608306107 50.9986464819036 0.1338968808914735 0.03474880824092795 2.4983644925456483e-09 8.60234420104854 -0.35805082787811304 GPS(ph)SVEDIK ddPTM_PC-9_AZD4547_30min_R2 1 GPSSVEDIK 9 0 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 GPS(0.63)S(0.37)VEDIK 112.85 0.0021408 128160000.0 104290.0 106770.0 121090.0 128900.0 118390.0 111570.0 113960.0 144840.0 98492.0 106620.0 True False 137452.05063324177 141281.3144988517 119484.26748119955 99184.09648514791 101953.59206015353 104593.51026268232 124102.21923022711 122458.30609208895 103698.08604459676 102887.26625260233 1.3359481269118196 1.3731661812452738 1.1613124911672676 0.964007501585642 0.9909252697009511 1.016583626645215 1.2061960993845358 1.1902182899041853 1.0078806622192074 1.0 16.650704913898963 -5.403838310722399 3.7008949687719106 1.0635226784198053 1.353924039706038 0.6909297381961237 0.07925612326921119 0.14531414667488088 3.51629795957587 0.023732679544585116 0.05376081731460181 3.946041871797672e-06 5.403838310722399 0.2904013612862326 GPS(ph)SVEDIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GPSSVEDIK 9 0 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 GPS(0.946)S(0.054)VEDIK;GPS(0.919)S(0.081)VEDIK 91.54899999999999 0.0077150000000000005 5339500.0 32901.0 46622.0 30185.0 49992.0 45003.0 40391.0 49436.0 40541.0 38653.0 33974.0 True False 38470.48947562942 51250.32404593605 30904.72487724999 47191.11031625078 36184.98520673859 38272.82485570826 44753.064194354396 39476.84170674016 39218.22700070833 40133.21726196398 0.9585697858339804 1.2770051229984056 0.770053511422314 1.1758616312322379 0.9016218403460191 0.9536445734187651 1.1151127980155442 0.9836450800607531 0.9772011733999997 1.0 15.292509193325785 -5.242702188183348 24.999717929545476 0.9914752548319701 1.1177873861265626 0.1498056916873175 0.12603779875851276 1536.0155133984686 2049389.8476796877 0.029540879698928203 0.07789141515794877 5.718706551414858e-06 5.242702188183348 0.1263121312945925 GPS(ph)SVEDIK ddPTM_PC-9_Lapatinib_30min_R1 1 GPSSVEDIK 9 0 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 GPS(0.5)S(0.5)VEDIK 80.014 0.019305000000000003 4499300.0 19195.0 27137.0 23402.0 22256.0 29727.0 25375.0 28319.0 25752.0 23674.0 27576.0 True False 18921.275780068103 27074.16594379232 21477.977894332354 23892.78048383956 27978.51630553067 24289.770402014095 29785.219254068816 26948.531932298007 21007.584821728116 32342.474857289682 0.5850286925647382 0.8371086647900744 0.6640796039605307 0.7387431107008917 0.8650703580658293 0.7510176790487453 0.9209319752274775 0.83322417505796 0.6495354766270526 1.0 14.981142458105262 -14.522878741390501 0.03135552608557052 2.14562404816763 4.2033854291055503e-13 0.3702163143374255 0.09797123037563918 1537.9849713769938 3.61363339654932 196.91599757292823 76.39904446602186 3.0000000268700364e-15 14.522878741390501 -2.1456240481672095 GPS(ph)SVEDIKAK ddPTM_PC-9_AZD4547_30min_R2 1 GPSSVEDIKAK 11 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 GPS(0.569)S(0.431)VEDIKAK 62.732 0.025394999999999997 23909000.0 145300.0 58818.0 150590.0 324660.0 282700.0 134240.0 117430.0 109390.0 84768.0 171500.0 True False 191502.37757225128 77829.76825132035 148593.07820624206 249814.65294699866 243451.98475720338 125845.95157894095 127881.04250794691 92486.28903212902 89248.6634226982 165495.83720053738 1.15714316934873 0.4702823319780011 0.8978659567502376 1.509492064409385 1.4710459723660823 0.7604176256496941 0.7727145568802963 0.5588435974982258 0.5392804129239355 1.0 17.336435403096665 -6.972837101088624 24.988118194931264 0.6931778326273895 1.081329784476576 0.2813396422160833 0.29835939990115573 317.2713466076448 291868.29053886235 0.11649376496798233 0.10273576599450505 1.0645422410118206e-07 6.972837101088624 0.3881519518491864 GPS(ph)WDPFR ddPTM_PC-9_AZD4547_30min_R2 1 GPSWDPFR 8 0 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 1 GPS(1)WDPFR 109.83 0.0037717 27164000.0 36243.0 44625.0 44610.0 63636.0 49829.0 53423.0 56326.0 105110.0 91386.0 51040.0 True False 47767.52009876873 59049.15856056256 44018.4422523438 48965.703366399255 42911.10346114862 50082.4513647331 61338.904882079514 88867.66468751333 96216.47739178342 49253.10513536688 0.9698377385036906 1.1988920982397409 0.8937191296135305 0.9941647989872368 0.871236510737994 1.0168384557092764 1.2453814782539316 1.804305828907032 1.9535108929141167 1.0 15.587927060913996 -7.5601894916728964 3.643366190106728 1.655290984557549 0.9956467946869909 0.5291922854396692 0.24792281292691984 0.15729969027202034 4.4249299819938 0.1195194887572376 0.06720124503988308 2.753027238469959e-08 7.5601894916728964 -0.6596441898705581 GPS(ph)WDPFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPSWDPFR 8 0 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 1 GPS(1)WDPFR 91.265 0.0088545 8386200.0 25948.0 38100.0 29558.0 26230.0 34991.0 25193.0 37835.0 36689.0 30293.0 27588.0 True False 30340.483903639157 41882.316205871975 30262.774819339247 24760.41813880737 28134.76473499521 23871.83473025817 34250.99489832105 35725.952625208796 30735.97781627447 32589.486013512156 0.930989948447161 1.2851481053891691 0.9286054651733932 0.7597670650141974 0.8633080228184653 0.7325011115658744 1.0509829729784632 1.0962416716359444 0.943125577480136 1.0 14.992118978278134 -10.524171103494737 21.412888856226253 0.9999999999826108 0.9555460069436306 0.007799899807835242 0.15349604323539376 0.0 0.0 0.16077693437170523 0.03899413426926702 2.991085975320335e-11 10.524171103494737 -0.04445399303898023 GPS(ph)WDPFR ddPTM_PC-9_Lapatinib_30min_R1 3 GPSWDPFR 8 0 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 1 GPS(1)WDPFR;GPS(1)WDPFR;GPS(1)WDPFR 93.556 0.0071363 47596300.0 60270.0 90150.0 85597.0 61369.0 174862.0 146414.0 254330.0 201087.0 151595.0 213506.0 True False 59410.53874783566 89941.26321379934 78559.54507397507 65882.28098098269 164576.9609519193 140152.2145277041 267497.96295375243 210430.23612418486 134520.7747338799 250410.22762113763 0.23725284431162225 0.35917567771983133 0.31372338829879204 0.26309740463420844 0.6572293892121642 0.559690456173179 1.0682389672935724 0.8403420184680269 0.5372015991990765 1.0 17.933933962573803 -6.57237692416122 1.5194360216533094 0.8351829076136962 0.2919725166296001 0.7102962818927006 0.15489796356195273 0.21734923718119079 1.0318323332136445 0.06356169824736957 0.06736402902891256 2.6768440835013444e-07 6.57237692416122 -0.5432103909840961 down GPSAGGGPGSGT(ph)SPQVEWTAR ddPTM_PC-9_AZD4547_30min_R2 2 GPSAGGGPGSGTSPQVEWTAR 21 0 Q7Z406;Q7Z406-6;Q7Z406-2;Q7Z406-4;Q7Z406-5;M0QY43;A0A2R8Y4C3;A0A2R8Y454 Q7Z406 MYH14 Myosin-14 1 GPSAGGGPGS(0.217)GT(0.391)S(0.391)PQVEWTAR;GPSAGGGPGS(0.002)GT(0.499)S(0.499)PQVEWTAR 208.4 2.4596e-24 36989000.0 44072.0 48845.0 61979.0 85174.0 65678.0 57710.0 47748.0 72009.0 51335.0 57422.0 True False 58085.97924545254 64633.19103396472 61157.1179636408 65538.4502251822 56559.7433848024 54101.3845770314 51997.47949986745 60881.66365220391 54048.46329752038 55411.673257896524 1.0482625019300407 1.1664183236833419 1.1036865405418075 1.1827552999555475 1.020718921833718 0.976353562276187 0.938384936651547 1.0987154885009338 0.9753985057619267 1.0 15.757902312092156 -6.387499687839818 5.852327108805369 1.00018794687253 1.126189746513182 0.5857160395513041 0.05118069836081425 0.1656466628302468 7.215868121776469 0.01571911726666651 0.017824640219707075 4.0973240431900096e-07 6.387499687839818 0.12600179964065195 GPSAGGGPGSGT(ph)SPQVEWTAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GPSAGGGPGSGTSPQVEWTAR 21 0 Q7Z406;Q7Z406-6;Q7Z406-2;Q7Z406-4;Q7Z406-5;M0QY43;A0A2R8Y4C3;A0A2R8Y454 Q7Z406 MYH14 Myosin-14 1 GPSAGGGPGS(0.245)GT(0.378)S(0.378)PQVEWTAR;GPSAGGGPGS(0.023)GT(0.488)S(0.488)PQVEWTAR;GPSAGGGPGS(0.001)GT(0.499)S(0.499)PQVEWTAR 194.1 1.9992e-18 20165900.0 42441.6 41878.1 54038.0 41316.8 47889.0 43243.1 38224.2 39696.2 33773.8 30542.5 True False 49626.12462019006 46035.48100527895 55326.47086025621 39001.9536468729 38505.49422406291 40975.35571087318 34603.32705675704 38654.21681160055 34267.67793124783 36079.61347570305 1.3754616482687536 1.2759416349146986 1.5334551989453682 1.0809969921972093 1.0672368829558971 1.1356927573092501 0.9590825323020664 1.0713589500517045 0.9497795189608829 1.0 15.138896262497694 -5.8561749312356035 6.760894042375083 1.0397777959241468 1.3816829614422577 0.8122688669838077 0.07876993863544149 0.08713174529266778 5.2529631345850145 0.02174260869125574 0.03254703145315073 1.3925957606666699e-06 5.8561749312356035 0.3419051655181109 GPSAGGGPGSGT(ph)SPQVEWTAR ddPTM_PC-9_Lapatinib_30min_R1 1 GPSAGGGPGSGTSPQVEWTAR 21 0 Q7Z406;Q7Z406-6;Q7Z406-2;Q7Z406-4;Q7Z406-5;M0QY43;A0A2R8Y4C3;A0A2R8Y454 Q7Z406 MYH14 Myosin-14 1 GPSAGGGPGSGT(0.5)S(0.5)PQVEWTAR 246.67 6.512699999999998e-61 17154000.0 27199.0 25646.0 33659.0 25511.0 23613.0 25838.0 20179.0 19020.0 29368.0 12690.0 True False 26811.13727231428 25586.618262685537 30891.686947497357 27387.164042201264 22224.129764944195 24732.968971319813 21223.76988339471 19903.73863592373 26060.266581249944 14883.449591637871 1.8014061261293801 1.719132255271059 2.0755730556479035 1.840108630299557 1.4932109406565677 1.6617766478824778 1.4259980357859436 1.3373068194557842 1.7509560818408432 1.0 13.86142132346646 -10.356498149757803 0.10129499070089297 2.585144162556925e-07 2.3646403193162584 0.6435039957000271 0.17250744564401121 31.8867510671016 0.6888112085157336 12.735435905300168 4.31332432488272 4.400498225938962e-11 10.356498149757803 2.3646400608018423 GPSAGGGPGSGTS(ph)PQVEWTAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPSAGGGPGSGTSPQVEWTAR 21 0 Q7Z406;Q7Z406-6;Q7Z406-2;Q7Z406-4;Q7Z406-5;M0QY43;A0A2R8Y4C3;A0A2R8Y454 Q7Z406 MYH14 Myosin-14 1 GPSAGGGPGSGT(0.153)S(0.847)PQVEWTAR 220.17 2.2886999999999998e-32 14049000.0 23579.0 28038.0 26009.0 27474.0 22395.0 25736.0 31395.0 20497.0 19747.0 20645.0 True False 27570.45899352195 30821.42734331333 26629.153199681787 25934.720851909806 18006.860513852636 24386.358854361322 28421.038319883428 19958.975468366654 20035.762517346302 24387.77507426993 1.1305032504834718 1.263806446034971 1.0919058060272417 1.0634311975130508 0.7383560189076284 0.9999419291056976 1.1653805332110327 0.8184008343354029 0.8215494220497722 1.0 14.573870524902338 -5.810700465011106 2.468668362424655 0.9303550830200119 1.1872090513178013 0.4408664362903558 0.12030595417056458 0.27256621057176333 3.3851311209677033 0.03746513080566672 0.06599305551478656 1.5463205765606314e-06 5.810700465011106 0.2568539682977894 GPSAGGGPGSGTS(ph)PQVEWTAR ddPTM_PC-9_Lapatinib_30min_R1 1 GPSAGGGPGSGTSPQVEWTAR 21 0 Q7Z406;Q7Z406-6;Q7Z406-2;Q7Z406-4;Q7Z406-5;M0QY43;A0A2R8Y4C3;A0A2R8Y454 Q7Z406 MYH14 Myosin-14 1 GPSAGGGPGS(0.026)GT(0.146)S(0.827)PQVEWTAR 219.99 2.4432999999999998e-32 15386000.0 58450.0 47222.0 63074.0 50023.0 43422.0 40971.0 43924.0 36082.0 42883.0 29684.0 True False 57616.49228158276 47112.660360311056 57888.29919268092 53701.858291836164 40868.003330936626 39218.76583806578 46198.16979821741 37758.50144381704 38053.06496199064 34814.83984855626 1.6549406095852561 1.3532350160233404 1.6627478237583075 1.5424990758377175 1.173867336707895 1.1264956555499466 1.3269677528082384 1.0845519211941126 1.0930127821216638 1.0 15.087414766439283 -6.272917526742059 5.354711877079153 1.1456042310700834 1.5486816434216333 0.7732314619409693 0.11118858304296063 0.08518924331836034 8.406753247375981 0.03363564915300744 0.040277044220128816 5.334361863052505e-07 6.272917526742059 0.4030774123515499 GPSHPLDLGTS(ph)SPNTSQIHWTPYR ddPTM_PC-9_AZD4547_30min_R2 1 GPSHPLDLGTSSPNTSQIHWTPYR 24 0 O60504-2;O60504;H0YAZ3 O60504-2 SORBS3 Vinexin 1 GPSHPLDLGT(0.122)S(0.439)S(0.439)PNTSQIHWTPYR 83.08200000000001 4.256e-05 7321000.0 6529.0 7889.9 27610.0 68804.0 40021.0 34999.0 12243.0 50120.0 18527.0 31899.0 True False 8605.08618836358 10440.155879596245 27243.873359946483 52942.300811203335 34464.774962745156 32810.50699725387 13332.603282166314 42375.10564302329 19506.29939637986 30782.225719299946 0.27954723829369926 0.33916182587961596 0.8850520949453315 1.719898401563906 1.119632325388879 1.0658913132679104 0.43312668173331575 1.3766095417997928 0.633687101584397 1.0 14.90980992954261 -5.308232718137213 4.140415859757579 1.0585418539818627 0.296785507042654 0.4285955535745628 0.33564525410231044 0.19041868850667373 7.04877181812546 0.09053002919183946 0.21451297329011185 4.917759452950241e-06 5.308232718137213 -0.7617563469392088 GPSLDIDT(ph)PDVNIEGPEGK ddPTM_PC-9_AZD4547_30min_R2 5 GPSLDIDTPDVNIEGPEGK 19 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GPS(0.019)LDIDT(0.981)PDVNIEGPEGK;GPS(0.007)LDIDT(0.993)PDVNIEGPEGK;GPSLDIDT(1)PDVNIEGPEGK;GPSLDIDT(1)PDVNIEGPEGK;GPS(0.066)LDIDT(0.934)PDVNIEGPEGK 189.56 1.7847e-47 0.0 34751.6 39095.96 48740.9 61690.3 54362.700000000004 63282.7 73867.0 113876.7 91760.2 72628.8 True False 45801.885921815876 51732.9645068327 48094.56381926168 47468.55444063392 46815.377473507084 59325.62276508233 80441.01990066007 96279.67264123836 96610.45683983888 70086.08781848622 0.6535089537375343 0.7381345730241684 0.6862212646798077 0.6772892583699528 0.6679696203724877 0.8464678884449637 1.1477458994285965 1.3737344405724299 1.3784541247336746 1.0 16.096840475323013 -7.22957900574815 2.285196962861834 1.2815950323317258 0.6885042082480526 0.8611645697007806 0.10277520059176681 0.09873333648845842 1.0105979935166656 0.04675746294823873 0.03134705018792443 5.894147424802351e-08 7.22957900574815 -0.5930908240836732 GPSLDIDT(ph)PDVNIEGPEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GPSLDIDTPDVNIEGPEGK 19 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GPSLDIDT(1)PDVNIEGPEGK;GPS(0.379)LDIDT(0.621)PDVNIEGPEGK 186.36 2.838e-47 2596700.0 23928.6 24420.0 18411.7 19936.0 33573.0 27195.0 33345.0 37445.0 25978.0 28588.0 True False 27979.239368607217 26844.256213842345 18850.704754761082 18819.050553384062 26994.611655797064 25768.846325938597 30186.320203105974 36462.10842625699 26357.879104452444 33770.778097516515 0.8285044332651842 0.7948959936998449 0.5581957484168051 0.5572584232155434 0.7993482287511235 0.7630516019361018 0.8938591854750856 1.079694057417599 0.7804936868301174 1.0 15.043487799774203 -7.125832268242838 1.790478738881232 0.9533098452220093 0.6929200881323555 0.4969039356471556 0.1114086118386052 0.31347764075931983 1.9846236435444677 0.05771821035167787 0.0399484343773392 7.484585118314318e-08 7.125832268242838 -0.26038975708965384 GPSLDIDT(ph)PDVNIEGPEGK ddPTM_PC-9_Lapatinib_30min_R1 2 GPSLDIDTPDVNIEGPEGK 19 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 GPSLDIDT(1)PDVNIEGPEGK;GPSLDIDT(1)PDVNIEGPEGK 122.94 0.00012327 0.0 23577.7 24906.3 19844.8 19367.4 31572.2 24142.3 29878.0 22967.1 31258.4 28976.0 True False 23241.47767437937 24848.630992588514 18213.237147143278 20791.743203752445 29715.18526933344 23109.790107450026 31424.936645823218 24034.235311520708 27737.74982645544 33984.46299190695 0.6838853884468938 0.7311762142160658 0.5359283491247331 0.611801434340857 0.8743756014744093 0.6800104539816735 0.9246853967740124 0.7072124493255701 0.8161891459947712 1.0 15.052587705688161 -6.255343974762453 24.932238186404557 0.8159663732016353 0.6396770442450534 0.4636223040519124 0.1006372908924387 467.03854086698016 1910342.2084685457 0.0289749240327727 0.036429361239977115 5.554641380935108e-07 6.255343974762453 -0.1762893289565819 GPSPAAAS(ph)PEGSPLR ddPTM_PC-9_Lapatinib_30min_R1 1 GPSPAAASPEGSPLR 15 0 Q9P107-2;Q9P107 Q9P107-2 GMIP GEM-interacting protein 1 GPS(0.006)PAAAS(0.63)PEGS(0.364)PLR 89.46600000000001 0.0045253 5150100.0 10852.0 12835.0 22161.0 11416.0 18189.0 19937.0 16002.0 19334.0 26907.0 15003.0 True False 10697.248489986932 12805.281346080053 20339.008123933818 12255.570722659611 17119.15878094989 19084.340985416948 16830.505261612674 20232.3282222371 23876.450316728842 17596.248559759115 0.6079277894749955 0.7277279189704372 1.155871835684745 0.696487701968867 0.9728868470350956 1.0845687318296329 0.9564825823216876 1.1498091853797998 1.3569057197414185 1.0 14.102980265166723 -4.17011577213489 0.3460545494707446 1.1566093900504324 2.4984582135222377e-14 0.5012789098140611 0.15718129157811087 8.906115054492073 0.6171615365239078 0.14982714221419188 4.669508298479902 6.759027724629029e-05 4.17011577213489 -1.1566093900504073 GPSPAPAS(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 1 GPSPAPASSPK 11 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 GPSPAPAS(0.579)S(0.421)PK 77.124 0.019851 12013000.0 85548.0 85546.0 68289.0 76772.0 77345.0 80835.0 79921.0 79313.0 81228.0 81836.0 True False 112750.4844910593 113197.07155679291 67383.44324075998 59073.40151557624 66606.98182188156 75780.37467136266 87033.8141725079 67056.99828142676 85521.54624975134 78970.94654893996 1.4277463981159888 1.4334014786899167 0.8532687802975876 0.7480396791111932 0.8434365387858662 0.9595981558154424 1.1020991640080091 0.8491350453786206 1.0829494894904397 1.0 16.269034362217113 -5.256874126960626 24.823523454207862 0.9220674642888885 1.430574013064431 0.7810855702779755 0.10597800224388354 152.90252811858065 831397.7434743627 0.02893849014036644 0.07132615420644861 5.5351051179435595e-06 5.256874126960626 0.5085065487755426 GPSPAPASS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 GPSPAPASSPK 11 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 GPS(0.001)PAPAS(0.148)S(0.851)PK;GPS(0.01)PAPAS(0.122)S(0.868)PK 77.062 0.01992 20026900.0 114368.0 108881.0 90774.0 104865.0 105321.0 101709.0 108110.0 107240.0 111709.0 107327.0 True False 150734.64499781947 144074.6539659969 89570.27744932215 80689.99439809957 90698.99712279241 95349.12015153826 117731.58056317874 90668.52213004413 117613.70968155639 103569.51439779656 1.4553958843416799 1.3910913341992273 0.8648324554781127 0.7790902068747775 0.8757306399490276 0.9206292093377508 1.1367397177415315 0.8754363932015606 1.1356016330231882 1.0 16.660239883837427 -5.239890745185634 9.528520807841263 0.9411250552327187 1.424249411839426 0.745895544020089 0.11076980813365364 0.1950736993403282 81.74201391644347 0.02947102838015259 0.07549165688198921 5.7558471811338e-06 5.239890745185634 0.4831243566067073 GPSPAPASS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GPSPAPASSPK 11 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 GPS(0.001)PAPAS(0.24)S(0.759)PK;GPSPAPAS(0.137)S(0.863)PK 96.334 0.0058477 19592100.0 150273.0 159360.0 119193.0 146500.0 149334.0 120663.0 144664.0 124061.0 114572.0 116056.0 True False 175711.25087296014 175180.2076264501 122035.01316196984 138292.07995940838 120073.07470308871 114335.21986492835 130960.37864333879 120804.53020349519 116247.39875107112 137096.03410120937 1.2816654546202524 1.2777919417940682 0.8901425483386272 1.0087241462967196 0.8758318611495817 0.8339790469833858 0.9552455656496889 0.8811672124250713 0.8479267800354675 1.0 17.06482731203627 -5.259549830638002 24.967695860008703 0.9083571125232766 1.2797287413127727 0.8713693620525211 0.05656046960356234 48.50049693924191 640852.1390194199 0.014524343846382445 0.03463072426427622 5.501107975702794e-06 5.259549830638002 0.37137162878949614 GPSPAPASS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 GPSPAPASSPK 11 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 GPSPAPAS(0.248)S(0.751)PK;GPSPAPAS(0.136)S(0.864)PK 92.906 0.0073917 30618000.0 230412.0 200852.0 166668.0 191185.0 185255.0 167036.0 169347.0 167447.0 167498.0 170247.0 True False 227126.28262761366 200386.9395343097 152965.2003970852 205245.38267446338 174358.6651253434 159892.25965993415 178114.95903876517 175227.1989153273 148632.61140786568 199673.96711013155 1.1374857018909261 1.003570682921249 0.766074829938728 1.0279025635888672 0.8732168126312364 0.8007666796730917 0.892028949074391 0.8775665724049021 0.7443765131680202 1.0 17.607286725249118 -4.9859056457214885 3.9720439779664503 0.8719004988321537 1.1240527329152512 0.4866349737631718 0.08635437357946711 0.1675501116500158 5.964921131800661 0.0212590959763845 0.09080224280000924 1.0329858065944313e-05 4.9859056457214885 0.2521522340830975 GPSPAPASS(ph)PKR ddPTM_PC-9_AZD4547_30min_R2 1 GPSPAPASSPKR 12 1 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 GPSPAPAS(0.132)S(0.868)PKR 68.809 0.043532 0.0 7851.4 6602.9 7507.0 12675.0 10545.0 8999.2 9327.8 9270.5 9568.4 11370.0 True False 10347.981880734837 8737.15829825296 7407.452275013334 9752.974576797893 9081.00876994947 8436.478601379673 10157.956129657021 7837.957239897196 10074.166089724245 10971.939760758654 0.9431314887222207 0.7963184713701736 0.6751269544430261 0.8889015788875899 0.8276575489803423 0.7689140466805053 0.9258122402373316 0.7143638600650903 0.9181754830403541 1.0 13.421530986041375 -8.517971334495567 18.993318323980542 1.0000000107223943 0.8167482541687487 0.3476467356623596 0.08150916156267281 13.633563175048598 52761.949493396896 0.0756070314968236 0.019521651789293156 3.0340914420723468e-09 8.517971334495567 -0.18325175655364556 GPSPAPASS(ph)PKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPSPAPASSPKR 12 1 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 GPS(0.009)PAPAS(0.213)S(0.778)PKR 56.286 0.035387 4747800.0 11218.0 9516.7 12224.0 11803.0 10506.0 13879.0 13203.0 12164.0 9857.7 6770.3 True False 13116.985834400497 10461.455082320783 12515.46651977815 11141.716175842292 8447.424717952037 13151.160807416873 11952.31625855775 11844.707888823348 10001.850213563825 7997.70179633469 1.6400943881668546 1.3080576581531485 1.5648828674149782 1.3931147296525221 1.056231519137592 1.6443674873504273 1.4944688565451942 1.4810139450625333 1.2505905406660232 1.0 12.965369774241038 -8.554633596747188 3.1067086291298134 1.000813741432931 1.4395284463951614 0.4213261163347539 0.1642562944025587 0.25131429250370857 6.364999670470623 0.15735960916878555 0.04184202319924355 2.7884727403228322e-09 8.554633596747188 0.4387147049622304 GPSPEGS(ph)SSTESSPEHPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPSPEGSSSTESSPEHPPK 19 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 GPS(0.192)PEGS(0.232)S(0.192)S(0.192)T(0.192)ESSPEHPPK 101.49 0.0010635999999999998 0.0 18045.0 14855.0 26099.0 30203.0 36202.0 32777.0 28883.0 24376.0 30496.0 18490.0 True False 21099.662095004187 16329.706226725148 26721.299141008698 28510.82382944716 29108.47797823145 31058.116419389204 26146.99314518851 23736.15582850689 30941.946307236176 21842.090633240525 0.9660092730726761 0.7476256051182976 1.2233855993776859 1.3053157002314504 1.332678197659913 1.4219388125843233 1.1970920542467003 1.0867162959384424 1.4166201773811422 1.0 14.414823331130355 -5.318216484952556 6.635768361360277 1.261958633146138 0.8576808602838941 0.5683992368912065 0.13599315419805275 0.13910657428007334 13.326971455995558 0.034755128197169194 0.07391489303695435 4.805997217725939e-06 5.318216484952556 -0.404277772862244 GPSPEGSS(ph)STESSPEHPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPSPEGSSSTESSPEHPPK 19 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 GPS(0.013)PEGS(0.21)S(0.383)S(0.383)T(0.011)ESSPEHPPK 81.017 0.0013005999999999998 3829700.0 7709.2 11758.0 30214.0 33734.0 40671.0 29447.0 32364.0 26618.0 29873.0 26381.0 True False 9014.215296359449 12925.256534085107 30934.416347233087 31843.99334710363 32701.80950921639 27902.747481519178 29298.247624930944 25919.305704102248 30309.836110836386 31163.66646811891 0.28925400371555066 0.414754038883965 0.9926436730055384 1.0218307714106973 1.0493569343861073 0.8953615104969846 0.9401412268002441 0.831715540615808 0.9726017361225447 1.0 14.927577358911636 -5.210603192994148 4.468797193240975 0.9599429412927691 0.3254575688529381 0.9378398823832758 0.06310720738082322 0.04863033653338218 2.1147260162063897 0.017855307711435602 0.04995941171452478 6.157392055391335e-06 5.210603192994148 -0.634485372439831 down GPSPRPPAT(ph)AYDAPASAFGSSLLGSGGSAFAPPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLR 35 1 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 GPS(0.21)PRPPAT(0.409)AY(0.352)DAPAS(0.028)AFGSSLLGSGGSAFAPPLR 63.74 3.7531e-05 4081100.0 4367.6 5235.6 4509.0 5252.2 4876.9 4764.1 5251.1 4705.2 4591.0 6069.0 True False 5106.948415967877 5755.35576712502 4616.511660477723 4957.936261862149 3921.306454119579 4514.262209281267 4753.677793328232 4581.69348557149 4658.134689681316 7169.261657822437 0.7123395210991701 0.8027822168891419 0.643931255520659 0.6915546535329069 0.5469609900262199 0.6296690544633311 0.6630637881854203 0.639074664065632 0.6497370178418288 1.0 12.807608832118238 -10.990079423433652 6.084640629559168 1.0001928715419606 0.6633640031634188 0.7249409176378259 0.06202350523137497 0.0001760217071719593 1.5413316121725032e-05 0.06513987233766556 0.01578980907322194 1.0231058703731388e-11 10.990079423433652 -0.33682886837854176 GPSPS(ph)PVGSPASVAQSR ddPTM_PC-9_Lapatinib_30min_R1 1 GPSPSPVGSPASVAQSR 17 0 O14497-2;O14497;H0Y488;A0A1B0GTU5;O14497-3;A0A087WUV6 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 GPS(0.398)PS(0.585)PVGS(0.017)PASVAQSR 140.68 9.1475e-05 103240000.0 12703.0 19082.0 20473.0 13545.0 18109.0 22097.0 17604.0 21087.0 22668.0 16009.0 True False 12521.852890555108 19037.81680139459 18789.788968065404 14541.144484795423 17043.864223663826 21151.962820622863 18515.448982966456 22066.779001878225 20114.891135377744 18776.134319348374 0.6669026050613426 1.0139369732659271 1.0007272342903384 0.7744482563597294 0.9077408551610391 1.1265344857927573 0.9861161338139083 1.1752567715250588 1.0713009820477164 1.0 14.19661244720727 -6.690480352722641 6.123575349031372 1.077135472684905 0.8800774730522263 0.4611417830195712 0.10760108853503977 0.19765461943535492 12.90848654127414 0.03556390301231124 0.0352999043373279 2.0394809226758635e-07 6.690480352722641 -0.19705799963267867 GPSPS(ph)SPTPPAAAAPAEQAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPSPSSPTPPAAAAPAEQAPR 21 0 Q86VQ1 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 GPS(0.091)PS(0.813)S(0.093)PT(0.003)PPAAAAPAEQAPR 139.38 2.3168999999999998e-10 0.0 6701.0 7534.7 7004.9 5317.1 8779.4 7837.0 6054.6 7988.8 7021.6 4642.6 True False 7835.346949217125 8282.695220902457 7171.923382231188 5019.200125270785 7059.139593450232 7426.013923749986 5481.064456491996 7779.1024648332705 7124.277616437883 5484.26662919862 1.4286954809055397 1.5102648687437636 1.307726970101593 0.9151998734978004 1.287161998263702 1.3540577849029747 0.9994161165160032 1.418439873695561 1.299039251393747 1.0 12.421082997148995 -5.5180792619995005 24.786384694449914 1.196228748151569 1.4543591698747151 0.33966072984085904 0.159100244741986 207.40494532653702 1071117.4191887586 0.04294062852305957 0.07706787720280273 3.033337526828397e-06 5.5180792619995005 0.25813042172314615 GPSPS(ph)SPTPPAAAAPAEQAPR ddPTM_PC-9_Lapatinib_30min_R1 1 GPSPSSPTPPAAAAPAEQAPR 21 0 Q86VQ1 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 GPS(0.023)PS(0.488)S(0.488)PTPPAAAAPAEQAPR 305.85 1.0304999999999997e-148 15152000.0 33459.0 31148.0 32822.0 29136.0 26775.0 33744.0 30111.0 25036.0 34214.0 25128.0 True False 32981.86852437087 31075.878719727425 30123.501856583924 31278.75863484674 25200.147141675363 32300.847781105967 31670.000245745454 26199.263958411513 30360.459030607657 29471.34131904466 1.1191166417341742 1.0544439896139337 1.0221286344072107 1.0613279625191037 0.855072962878374 1.0960087439329698 1.0746032867285888 0.8889742640074988 1.0301688919393852 1.0 14.847025102389958 -4.49514691545069 0.8860431916530861 0.996513445674423 1.2445177103556386 0.20953527567068164 0.07242250401617277 5.660948245517023 2.4658967855386087 0.025364139953712988 1.534764343943916 3.197813153429456e-05 4.49514691545069 0.2480042646812156 GPSPSAS(ph)QR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPSPSASQR 9 0 Q8IY92;Q8IY92-2 Q8IY92 SLX4 Structure-specific endonuclease subunit SLX4 1 GPS(0.048)PS(0.095)AS(0.858)QR 75.189 0.026333999999999996 2142300.0 8936.9 9273.2 8394.3 8666.8 14227.0 11370.0 10105.0 8883.7 10056.0 8663.9 True False 10449.740658179158 10193.782011556226 8594.451947560025 8181.227294144709 11439.321479374037 10773.73718425894 9147.781246135432 8650.512288058202 10203.049975917076 10234.596486605333 1.0210212656508146 0.9960121070623036 0.8397450704390867 0.7993697948768183 1.117711039643371 1.0526782563786676 0.8938096639283937 0.8452226034880493 0.9969176595550647 1.0 13.321166602746215 -5.019868530921489 24.154933766777564 0.9393636922685055 1.0147690661364828 0.0704867760947141 0.09598757885661022 1219.0193466139924 1482024.1788582483 0.026188934330182732 0.07155111704595607 9.552817239356633e-06 5.019868530921489 0.0754053738679773 GPSPSS(ph)PTPPAAAAPAEQAPR ddPTM_PC-9_AZD4547_30min_R2 1 GPSPSSPTPPAAAAPAEQAPR 21 0 Q86VQ1 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 GPSPSS(0.969)PT(0.03)PPAAAAPAEQAPR 167.9 1.7519e-08 14282000.0 14626.0 16874.0 22275.0 30653.0 25786.0 24398.0 19262.0 24553.0 21546.0 18591.0 True False 19276.763760301063 22328.190510945267 21979.61894577354 23586.42443412906 22206.058998759312 22872.38920309152 20976.28068456158 20758.898021810674 22684.877572969217 17940.134748660006 1.074504959431305 1.2445943591707425 1.2251646519776143 1.314729502569137 1.2377866337050751 1.2749285065877176 1.169237632740097 1.1571205184710893 1.264476431798463 1.0 14.130903105954532 -10.67298251591547 5.145107938953536 0.9999906369831658 1.2209173939582112 0.5003857652862258 0.06531152344327318 7.064318836594953e-06 1.167029772105342e-06 0.06368542802497279 0.015445330702263846 2.1233299425542415e-11 10.67298251591547 0.22092675697504538 GPSPSS(ph)PTPPAAAAPAEQAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GPSPSSPTPPAAAAPAEQAPR 21 0 Q86VQ1 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 GPS(0.001)PS(0.226)S(0.774)PTPPAAAAPAEQAPR;GPSPS(0.008)S(0.991)PTPPAAAAPAEQAPR 310.98 1.9002999999999994e-149 24946000.0 29854.0 31792.0 34831.0 31700.0 33977.0 34491.0 36190.0 26916.0 30788.0 28475.0 True False 34907.6925566226 34948.099653991645 35661.50313730308 29923.951772786666 27319.45075593532 32682.231242064667 32761.821207089695 26209.483519859336 31238.216254826464 33637.29209202402 1.037767619971401 1.0389688788973128 1.0601775862260634 0.8896064430787562 0.8121774690184775 0.9716070827774566 0.9739732056153856 0.779179353919338 0.9286780924387662 1.0 15.037773948321634 -5.762568200617955 24.9974105568749 0.9001084066393579 1.0449711357387261 0.4717262360719494 0.06644378473299903 24.668973762793254 546310.2278128965 0.01852181462107916 0.02932394040509082 1.7275546679482637e-06 5.762568200617955 0.14486272909936826 GPSQEEEDNHS(ph)DEEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GPSQEEEDNHSDEEDR 16 0 E7ERS3;Q86VM9;H3BPD0 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 GPSQEEEDNHS(1)DEEDR;GPSQEEEDNHS(1)DEEDR 85.97399999999999 0.0026059 3369800.0 5912.6 8574.3 6730.1 6411.3 8880.599999999999 4616.5 6701.9 3795.8 5616.9 5795.6 True False 6913.486400826918 9425.499838425405 6890.571108046384 6052.095646715046 7140.5101799205095 4374.40261311622 6067.047514445826 3696.1642719825427 5699.036536369198 6846.296402055643 1.0098140651274023 1.376729736035872 1.0064669572263112 0.8839955636302669 1.0429741513640174 0.6389443804686543 0.8861794988344585 0.5398779215683309 0.8324262055989903 1.0 12.74110803808478 -5.944878642842496 1.0233665475625369 0.7665697085154124 1.1994629306693114 0.4227242675828343 0.1663276654727331 0.4840394811881911 1.018111868406222 0.06519097771462484 0.14839793352754665 1.1353280219431664e-06 5.944878642842496 0.432893222153899 GPSQEEEDNHS(ph)DEEDRASEPK ddPTM_PC-9_AZD4547_30min_R2 2 GPSQEEEDNHSDEEDRASEPK 21 1 E7ERS3;Q86VM9;H3BPD0 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 GPSQEEEDNHS(0.997)DEEDRAS(0.003)EPK;GPSQEEEDNHS(1)DEEDRASEPK 60.09 0.004430399999999999 30030000.0 23745.9 20431.0 24569.0 35679.0 33496.0 31810.0 25810.0 28708.0 28156.0 26239.0 True False 31296.602254596834 27034.9212000191 24243.19900690058 27453.75778505501 28845.658583046712 29820.91567138048 28107.03999940478 24271.838244212144 29644.26867838677 25320.380596530034 1.2360241638265814 1.067713855917475 0.9574579226594614 1.0842553365417162 1.1392268956257234 1.1777435792362145 1.110055984042224 0.9585889971787555 1.1707671046006825 1.0 14.628011469963402 -14.522878744991884 0.3077866214226614 0.1789786328371411 1.098542298504747 0.10481525565948913 0.08559131432134888 768.8954403547904 6.9981082759268824 408.8628459205521 0.08461591743047252 3.0000000019925686e-15 14.522878744991884 0.919563665667606 GPSQEEEDNHS(ph)DEEDRASEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GPSQEEEDNHSDEEDRASEPK 21 1 E7ERS3;Q86VM9;H3BPD0 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 GPS(0.001)QEEEDNHS(0.999)DEEDRASEPK;GPS(0.002)QEEEDNHS(0.996)DEEDRAS(0.002)EPK 68.895 0.0072045 6594400.0 22437.4 28247.7 25265.9 25108.5 31619.3 22226.3 30151.1 28088.5 26580.3 22133.5 True False 26235.60866114973 31051.94497345434 25868.334877459336 23701.752147855324 25423.725146044235 21060.71370083506 27294.969532939547 27351.2066372258 26968.98660251279 26146.128341310396 1.0034223162477924 1.1876307102949866 0.9893753499476191 0.9065109693662369 0.9723705481042569 0.8055002800380018 1.0439392470132567 1.0460901239443319 1.0314715146526032 1.0 14.674309710865865 -5.437859824644607 8.483481165975052 0.9685416268237834 1.094782767436188 0.2694055067321536 0.08004126159204471 0.4320014056971912 39.65045730293208 0.02157318674176417 0.04499720767166167 3.6487169598433684e-06 5.437859824644607 0.12624114061240466 GPSQEEEDNHS(ph)DEEDRASEPK ddPTM_PC-9_Lapatinib_30min_R1 5 GPSQEEEDNHSDEEDRASEPK 21 1 E7ERS3;Q86VM9;H3BPD0 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 GPSQEEEDNHS(0.992)DEEDRAS(0.008)EPK;GPSQEEEDNHS(0.999)DEEDRASEPK;GPSQEEEDNHS(1)DEEDRASEPK;GPS(0.055)QEEEDNHS(0.942)DEEDRAS(0.003)EPK;GPS(0.002)QEEEDNHS(0.994)DEEDRAS(0.005)EPK 68.08800000000001 0.0014639000000000002 57196800.0 79853.4 75094.3 95889.2 81757.4 88961.7 81278.3 80640.59999999999 86762.8 89785.9 71695.6 True False 78714.67587268009 74920.42376213001 88005.560119016 87770.11193069106 83729.14771143158 77802.21657797141 84815.77569051391 90794.11643117358 79673.26645455773 84088.08893161788 0.936097809722997 0.8909754605442015 1.0465877062634148 1.0437876879574166 0.9957313666567188 0.9252465785165095 1.0086538624927937 1.0797500286278259 0.9474976476079701 1.0 16.35961383691111 -5.255013384481736 24.96932146439568 1.006961934588816 0.9135366286645726 0.4099860269831278 0.04430950090314773 492.73557571490574 1914597.7547424585 0.011725583591456416 0.029455403275790784 5.558871251721711e-06 5.255013384481736 -0.09342530592424347 GPSS(ph)PPTTTAPMR ddPTM_PC-9_AZD4547_30min_R2 1 GPSSPPTTTAPMR 13 0 Q9NXL9-4;Q9NXL9 Q9NXL9-4 MCM9 DNA helicase MCM9 1 GPS(0.131)S(0.812)PPT(0.017)T(0.017)T(0.023)APMR 70.72800000000001 0.024248 7415800.0 16383.0 16135.0 21869.0 32507.0 21329.0 23365.0 20529.0 26176.0 19243.0 21301.0 True False 21592.453212430763 21350.323212877895 21579.002771049232 25013.01337814351 18367.836515339226 21903.98285639124 22356.041230057366 22131.100664640413 20260.145694636896 20555.25847351979 1.0504588516971038 1.0386793841771604 1.049804496443004 1.2168668864157755 0.8935833397084985 1.0656145669298658 1.0876069137664908 1.0766637010743842 0.9856429546111974 1.0 14.327219892833964 -6.26145464851078 24.999999496885053 1.027860987101966 1.0825651861640369 0.1841647371272599 0.07073379337838186 3.246760877569756 5314209.973359083 0.02184054729315766 0.026403733980542358 5.477032922551566e-07 6.26145464851078 0.05470419906207091 GPSS(ph)TGASGQAK ddPTM_PC-9_AZD4547_30min_R2 2 GPSSTGASGQAK 12 0 Q9NWH9;H7BXE3 Q9NWH9 SLTM SAFB-like transcription modulator 1 GPS(0.045)S(0.942)T(0.014)GASGQAK;GPS(0.09)S(0.9)T(0.01)GASGQAK 164.22 1.2963e-12 0.0 56694.0 44082.0 44492.0 53138.0 41037.0 49894.0 36790.0 37737.0 58265.0 62307.0 True False 74721.51269154316 58330.64442950629 43902.00700944364 40887.85507391608 35339.720900181754 46774.1202926079 40064.23872832628 31905.61375999139 61344.768949645 60125.65089477482 1.2427559881607333 0.9701457458080587 0.7301710061530313 0.6800401237314407 0.5877644628251821 0.7779395249203492 0.6663418712662624 0.5306489540683563 1.020276172261382 1.0 15.875692986520793 -4.9329483601623805 2.080100449872818 0.7205036458988894 1.3043105847263905 0.5036537786319886 0.15183451118843955 0.36568524682495646 2.2820601589252143 0.038931568871024794 0.3630015149672232 1.1669483649476086e-05 4.9329483601623805 0.5838069388275011 GPSS(ph)TGASGQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GPSSTGASGQAK 12 0 Q9NWH9;H7BXE3 Q9NWH9 SLTM SAFB-like transcription modulator 1 GPS(0.001)S(0.981)T(0.017)GAS(0.001)GQAK;GPS(0.001)S(0.982)T(0.018)GASGQAK 143.76 3.3635e-05 0.0 20251.8 38690.0 33327.0 22085.1 52780.0 49720.0 27077.0 28036.0 46028.0 50791.0 True False 23680.02974871742 42530.88750669779 34121.64207335132 20847.743447860255 42438.13788440021 47112.59567294237 24512.070539496217 27300.084706597438 46701.07242357908 59999.00623866524 0.3946736993363278 0.7088598657370687 0.5687034538142445 0.34746814580447694 0.7073140130952993 0.7852229332855439 0.40854127553365827 0.4550089479482813 0.7783640988620815 1.0 15.872650985163563 -8.51857923011811 4.117467006766967 0.9991433814272422 0.5563273059457117 0.5113965724312878 0.14183039491318236 0.1483083353623897 7.482621211435969 0.13948649102534016 0.036520384186516576 3.0298474998972285e-09 8.51857923011811 -0.44281607548153057 GPSS(ph)TGASGQAK ddPTM_PC-9_Lapatinib_30min_R1 2 GPSSTGASGQAK 12 0 Q9NWH9;H7BXE3 Q9NWH9 SLTM SAFB-like transcription modulator 1 GPSS(0.992)T(0.008)GASGQAK;GPS(0.027)S(0.971)T(0.002)GASGQAK 187.62 2.0457999999999998e-35 6391600.0 30959.0 53840.0 45337.0 41262.0 56496.0 35270.0 70971.0 70454.0 58147.0 44360.0 True False 30517.518982814727 53715.33678791977 41609.566865880945 44296.54512599696 53173.0163554096 33761.58431838569 74645.53111623006 73727.55004497235 51597.87254494484 52027.56689401549 0.5865644081527293 1.0324399158880986 0.7997599993603991 0.8514052793633947 1.022016202751274 0.6489172247312828 1.4347303856874427 1.4170862572751393 0.9917410254847018 1.0 15.666988619787066 -7.26180308893762 24.999924983787274 1.2456466061668288 0.8422241125369281 0.493107889817203 0.19054626684419163 26.764894174712392 1839619.911791088 0.07353655133950078 0.05307205033474615 5.4726403861554456e-08 7.26180308893762 -0.4034224936299007 GPSS(ph)VEDIK ddPTM_PC-9_AZD4547_30min_R2 3 GPSSVEDIK 9 0 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 GPS(0.402)S(0.598)VEDIK;GPS(0.297)S(0.703)VEDIK;GPS(0.375)S(0.625)VEDIK 132.25 0.0012075999999999999 75397800.0 126243.0 143031.0 166601.0 169713.0 182401.0 155785.0 147568.0 191919.0 139779.0 138229.0 True False 166385.64798247576 189262.97362634883 164391.76188484053 130588.28988971206 157077.76962044128 146043.73932304358 160701.26612290464 162262.32840988424 147167.43257551585 133389.64478363332 1.2473655526436411 1.4188730611986087 1.2324177199174242 0.9789987078947152 1.1775859353642604 1.0948656438806477 1.2047506864837412 1.2164537110289504 1.103289785456967 1.0 17.025287146962548 -5.52443166615744 24.99980065536363 1.124342517518804 1.3312508488563248 0.5327249304642592 0.08390303357582705 35.872884940613034 577498.9503506336 0.022105826914219397 0.0386555296770456 2.989291958568323e-06 5.52443166615744 0.20690833133752085 GPSS(ph)VEDIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GPSSVEDIK 9 0 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 GPSS(1)VEDIK;GPS(0.004)S(0.996)VEDIK;GPS(0.015)S(0.985)VEDIK;GPS(0.005)S(0.995)VEDIK 144.55 0.00054254 193753000.0 343670.0 367171.0 325758.0 384810.0 409261.0 303729.0 391781.0 317100.0 293836.0 257200.0 True False 401846.54320809565 403621.31033139775 333525.30616409477 363250.3432708522 329069.24495467014 287800.9165556535 354668.6674311909 308776.46099522256 298132.7956169026 303828.32400592073 1.3226105384442854 1.328451886939719 1.0977426388910183 1.195577615942658 1.0830762603563502 0.9472484749316693 1.167332468398435 1.0162859634811579 0.9812541230062963 1.0 18.212896843941472 -4.560236448717805 0.46237025884792826 1.0103025797293992 1.6762870560119694 0.7184309394722685 0.0688184105007908 3.1990654025877157 0.45562958905856166 0.04693928483972542 1.2184145910181505 2.7527295901216885e-05 4.560236448717805 0.6659844762825702 GPSS(ph)VEDIK ddPTM_PC-9_Lapatinib_30min_R1 5 GPSSVEDIK 9 0 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 GPSS(1)VEDIK;GPS(0.005)S(0.995)VEDIK;GPS(0.1)S(0.9)VEDIK;GPS(0.001)S(0.999)VEDIK;GPS(0.082)S(0.918)VEDIK 147.74 0.00036487 419258100.0 415610.0 550070.0 575393.0 498212.0 611597.0 562357.0 544178.0 504641.0 545174.0 443636.0 True False 409683.3251864605 548796.3467111998 528086.4086212121 534852.1724665111 575624.0669059661 538306.3020281941 572352.8741565964 528088.463142543 483770.7631832731 520317.89149218734 0.7873712049600201 1.0547328002451366 1.0149303286626297 1.027933463776619 1.1062930495339487 1.0345719623140748 1.100006137623254 1.014934277251299 0.929760000748575 1.0 18.989033790675627 -4.758798308555133 24.99873066586954 1.035879863453508 0.7873708752089249 0.6998983292453946 0.04787158250280322 40.18842196117203 380322.9659405633 0.012107696058265243 0.08079252081939084 1.742615976771728e-05 4.758798308555133 -0.24850898824458312 GPSSSLNT(ph)PGSFR ddPTM_PC-9_Lapatinib_30min_R1 2 GPSSSLNTPGSFR 13 0 Q9NXR1;Q9NXR1-1;I3L533;I3L2R9;I3L2T8;I3L2R3;I3L522 Q9NXR1 NDE1 Nuclear distribution protein nudE homolog 1 1 GPSSSLNT(0.5)PGS(0.5)FR;GPSSSLNT(0.984)PGS(0.016)FR 101.72 0.00472 12930800.0 29873.0 47010.0 50187.0 47634.0 52802.0 43277.0 35731.0 40998.0 48840.0 36318.0 True False 29447.005541962724 46901.15123328576 46060.818587422335 51137.16326236584 49696.290172726156 41426.143593614346 37580.97634687425 42902.916750557364 43339.1248919997 42595.5179093069 0.6913169973578066 1.101081839951947 1.081353645834138 1.2005292052381087 1.166702334234743 0.972547010270368 0.8822753705422843 1.007216694533565 1.0174573997263296 1.0 15.378414011169347 -6.936765497049885 24.999944382093403 0.970204586583214 1.06225862419332 0.061567540282427835 0.1348031279059764 165.21312392758097 65316.027617218795 0.04900651585943632 0.04321968005902683 1.1567366685918935e-07 6.936765497049885 0.09205403761010611 GPSSVEDIK ddPTM_PC-9_Lapatinib_30min_R1 2 GPSSVEDIK 9 0 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 0 ; 125.82 0.0065167 44884000.0 139438.0 133038.0 136787.0 138470.0 129123.0 90924.0 140731.0 115194.0 118465.0 139404.0 False True 137449.58855020278 132729.95868483023 125540.9008730895 148653.54572237912 121528.23900558542 87035.39247419615 148017.36257792855 120546.33377637205 105122.22420824633 163499.79565584572 0.8406713170426428 0.8118050432565458 0.7678352157536837 0.9091971346269031 0.7432929106614473 0.5323272247838086 0.9053061013574202 0.7372873665855378 0.6429501871031105 1.0 17.31892930706242 -6.413682240532966 21.091321628290242 0.7428794552528719 0.8262970215235529 0.06280803629603182 0.1255187679426262 20.61395301489106 3953.1558031417253 0.03775251153969504 0.04280724475473519 3.857605031323185e-07 6.413682240532966 0.08341756627068098 GPST(ph)PNVK ddPTM_PC-9_Lapatinib_30min_R1 2 GPSTPNVK 8 0 Q9Y4E8-2;Q9Y4E8-3 Q9Y4E8-2 USP15 Ubiquitin carboxyl-terminal hydrolase 15 1 GPS(0.035)T(0.965)PNVK;GPS(0.005)T(0.995)PNVK 93.598 0.017372 24865000.0 282800.0 243145.0 261930.0 239014.0 249770.0 256620.0 206655.0 211643.0 277090.0 200005.0 True False 278767.2201408314 242582.01269128473 240395.1264790387 256591.8868873304 235079.01966671366 245644.9608104376 217354.58472931923 221476.7064207575 245881.20631294415 234575.59776008903 1.188389682484958 1.0341314911169244 1.0248087557892598 1.0938558372544718 1.0021460966589522 1.0471888941392349 0.9265865111494568 0.9441591901953571 1.0481960129732586 1.0 17.83969341609999 -1.5228787452803376 0.501630993290497 0.9903478788234849 6.476314812805395 0.5527955341918936 0.04708059940736076 87.73042425691847 0.9280361087191907 0.0268566978021764 507.5818080794506 0.029999999999999995 1.5228787452803376 5.48596693398191 GPSTPKS(ph)PGASNFSTLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GPSTPKSPGASNFSTLPK 18 1 Q9Y4E8 Q9Y4E8 USP15 Ubiquitin carboxyl-terminal hydrolase 15 1 GPST(0.001)PKS(0.998)PGASNFSTLPK;GPS(0.007)T(0.007)PKS(0.947)PGAS(0.005)NFS(0.025)T(0.01)LPK 73.404 0.0033407 33768000.0 46199.0 15602.5 21374.5 63402.0 65365.0 83085.0 69499.0 110411.0 77669.0 55812.0 True False 54019.57822815729 17151.41308666975 21884.149143242663 59849.791492057404 52557.19747657859 78727.87633721667 62915.55159081306 107512.82824012454 78804.76218968794 65930.27379245113 0.8193440603357909 0.2601447271501176 0.33192868593469044 0.9077740474802953 0.7971633432318049 1.1941081358929657 0.9542740833880285 1.6307050169179567 1.1952743050600059 1.0 16.008653452084566 -6.406330441109988 1.0881400430796961 1.256848587560071 0.45901463537980436 0.6054378155985276 0.240751296236676 0.31395378503496274 0.7842099594556594 0.10949748799233161 0.14191397031723013 3.9234629775543274e-07 6.406330441109988 -0.7978339521802666 GPTEADELMK ddPTM_PC-9_Lapatinib_30min_R1 2 GPTEADELMK 10 0 P11413;P11413-2;P11413-3 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ; 107.15 0.010196 7551000.0 88125.0 99606.0 107822.0 89875.0 76504.0 61244.0 58964.0 42523.0 54730.0 52689.0 False True 86868.32133985421 99375.36842677428 98957.29136495631 96484.70731421109 72004.185132651 58624.736886737 62016.86740693222 44498.773817843605 48565.73106755007 61796.22344632055 1.4057221703088798 1.6081139410258127 1.6013485265958982 1.5613366308383356 1.1651874680529242 0.9486783110243222 1.0035705088160174 0.720088887899397 0.7859012793837931 1.0 15.915231052925925 -6.519301758969105 1.8372426080187785 0.8632076746500262 1.5628729629479632 0.9053870520503978 0.09925617745929144 0.09759066370877174 0.6648904728761096 0.03885210952077257 0.04238328216877118 3.024810981349473e-07 6.519301758969105 0.699665288297937 GPTS(ph)SPCEEEGDEGEEDRTSDLRDEASSVTR ddPTM_PC-9_Lapatinib_30min_R1 1 GPTSSPCEEEGDEGEEDRTSDLRDEASSVTR 31 2 E7ERS3;Q86VM9 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 GPT(0.176)S(0.434)S(0.388)PCEEEGDEGEEDRT(0.001)S(0.001)DLRDEASSVTR 40.918 0.019244 7400000.0 7875.1 7680.4 11005.0 9846.1 11483.0 13445.0 10008.0 12246.0 14030.0 10906.0 True False 7762.799629883528 7662.616505682367 10100.211380528486 10570.215039626743 10807.592516446613 12869.988691825783 10526.165270479918 12814.993866220926 12449.793657550292 12791.08756866845 0.6068912895959193 0.5990590295427117 0.7896288197782948 0.8263734403256141 0.8449314773608169 1.006168445234524 0.8229296542589216 1.0018689808371755 0.9733178348372696 1.0 13.642851314857266 -4.944241635479872 0.4608831443537758 0.9844108456425872 0.31131832523847824 0.8483272828062525 0.0567199554056673 1.512739085964499 0.27880089319618434 0.03967798524417759 0.5488340880717327 1.1369945016920663e-05 4.944241635479872 -0.6730925204041089 GPTSS(ph)PCEEEGDEGEEDRTSDLRDEASSVTR ddPTM_PC-9_Lapatinib_30min_R1 1 GPTSSPCEEEGDEGEEDRTSDLRDEASSVTR 31 2 E7ERS3;Q86VM9 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 GPT(0.104)S(0.254)S(0.637)PCEEEGDEGEEDRT(0.002)S(0.004)DLRDEASSVTR 59.332 0.00032654 6739400.0 12859.0 11849.0 19987.0 17153.0 16506.0 20217.0 16579.0 14703.0 16225.0 12569.0 True False 12675.62830194821 11821.564368500385 18343.746012051135 18414.48884073059 15535.149532044572 19352.36603812882 17437.37949832998 15386.155055940413 14397.569643175571 14741.534902860247 0.8598581074138218 0.8019222181678443 1.2443579405352128 1.2491568186130804 1.0538352779689408 1.312778225988798 1.1828740774440434 1.0437281570289598 0.976666930414557 1.0 13.847599126605102 -5.253354005901871 24.92286195795509 1.1440201737441278 0.8308901205748241 0.5476863324138546 0.10942089132628822 422.5778615977528 1302572.4727113035 0.028906786286132927 0.07360352406787102 5.580151551291568e-06 5.253354005901871 -0.31313005316930365 GPTSSPCEEEGDEGEEDRT(ph)SDLRDEASSVTR ddPTM_PC-9_Lapatinib_30min_R1 1 GPTSSPCEEEGDEGEEDRTSDLRDEASSVTR 31 2 E7ERS3;Q86VM9 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 GPTSSPCEEEGDEGEEDRT(0.481)S(0.481)DLRDEAS(0.018)S(0.018)VT(0.002)R 62.052 0.0044096000000000005 0.0 4234.0 3437.5 5634.1 3080.3 3881.5 4111.4 3915.2 3428.2 5332.3 4053.0 True False 4173.622383579492 3429.540679949371 5170.886046254932 3306.835537579574 3653.1978013226144 3935.5650061415054 4117.909898779271 3587.486687259398 4731.720222391687 4753.55564971697 0.8780001100498301 0.7214685032989081 1.0877933124781678 0.695655164524363 0.7685189930489461 0.8279202550991134 0.8662799391071512 0.7546954220411829 0.9954065064271239 1.0 12.214791334784834 -8.278215293328637 23.524222114775313 0.9977034126446547 0.8256210468516251 0.30404538410037696 0.10448771333054507 523.3750306580027 733894.0865352827 0.0954669472179017 0.024984303583513893 5.2696856189864e-09 8.278215293328637 -0.1720823657930296 GPTSSPCEEEGDEGEEDRTSDLRDEAS(ph)SVTR ddPTM_PC-9_Lapatinib_30min_R1 1 GPTSSPCEEEGDEGEEDRTSDLRDEASSVTR 31 2 E7ERS3;Q86VM9 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 GPTSSPCEEEGDEGEEDRT(0.095)S(0.095)DLRDEAS(0.328)S(0.328)VT(0.154)R 41.784 0.016108 10101000.0 9765.5 6217.6 13097.0 9107.0 9411.9 10256.0 9579.8 5642.5 12006.0 8965.6 True False 9626.242179226634 6203.203529208209 12020.21521588201 9776.759160061416 8858.310546507359 9817.37478790371 10075.795169678604 5904.671148958972 10653.75785121516 10515.292014088933 0.9154517217713874 0.5899221363417047 1.1431175853011692 0.9297658255198247 0.8424217353772521 0.9336283552325396 0.9582040285879395 0.5615318282219445 1.0131680448760436 1.0 13.360201294424492 -12.641499590898823 1.141786504908536 3.4392469259159344 0.8711765688488431 0.04503567548210796 0.16934698465912215 403950.3524053293 7440.138191064852 2543823.5667648623 0.047995820477262155 2.28297107521471e-13 12.641499590898823 -2.568070357067091 GPTSTSIDNIDGT(ph)PVRDER ddPTM_PC-9_AZD4547_30min_R2 5 GPTSTSIDNIDGTPVRDER 19 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 GPTSTSIDNIDGT(1)PVRDER;GPTSTSIDNIDGT(1)PVRDER;GPTSTSIDNIDGT(1)PVRDER;GPTSTSIDNIDGT(1)PVRDER;GPTSTSIDNIDGT(1)PVRDER 149.8 2.1569e-05 120622900.0 112034.0 109429.0 140058.0 191741.0 168597.0 151302.0 115361.0 166425.0 127171.0 137706.0 True False 147658.48154803563 144799.78424927263 138200.73940772846 147538.07481891967 145190.21674605727 141841.06202172962 125627.90551613079 140707.8403160445 133892.999435258 132884.9548544441 1.1111753148411252 1.0896627417895386 1.0400029074706538 1.1102692173130202 1.0926008659527466 1.0673974505021702 0.9453884802364395 1.0588696099582469 1.0075858443261547 1.0 17.019818247330953 -7.034071529201207 14.491193005993727 1.0076507884295487 1.0865547994794476 0.6239548507554273 0.03152830261746662 2.9870808509614446 1269.726626462702 0.011760723453056898 0.009157619222442254 9.245458867739679e-08 7.034071529201207 0.07890401104989886 GPTSTSIDNIDGT(ph)PVRDER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GPTSTSIDNIDGTPVRDER 19 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 GPTSTSIDNIDGT(1)PVRDER;GPTSTSIDNIDGT(1)PVRDER;GPTSTSIDNIDGT(1)PVRDER;GPTSTSIDNIDGT(1)PVRDER 180.31 3.3458000000000006e-09 84139000.0 124528.0 106550.0 137355.0 136507.0 153907.0 143367.0 149560.0 126317.0 108508.0 104146.0 True False 145608.13085988796 117127.57983558178 140630.06412173822 128858.9553516654 123750.02818064364 135848.58213682062 135392.59407936837 123001.31259392484 110094.72422303219 123026.8453807178 1.1835476266118203 0.9520489570639628 1.1430843706228966 1.0474051817950758 1.0058782520001053 1.104219015910103 1.1005126048740308 0.999792461663843 0.8948837457575541 1.0 16.908613631235227 -7.964691769391505 4.879869626902799 0.9463987396265516 1.0711216534313182 0.3847729827435873 0.06662462317179423 0.18233362623231367 10.427211197972134 0.03751637719337379 0.016532691326828945 1.0846964794980575e-08 7.964691769391505 0.12472291380476652 GPTSTSIDNIDGT(ph)PVRDER ddPTM_PC-9_Lapatinib_30min_R1 4 GPTSTSIDNIDGTPVRDER 19 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 GPT(0.001)S(0.001)T(0.003)S(0.002)IDNIDGT(0.993)PVRDER;GPTSTSIDNIDGT(1)PVRDER;GPTSTSIDNIDGT(1)PVRDER;GPTSTSIDNIDGT(1)PVRDER 234.51 1.7732e-42 86166100.0 112040.0 87402.0 105750.0 80889.0 92154.0 96952.0 84015.0 78780.0 100986.0 83523.0 True False 110442.2890543804 87199.62603896274 97055.64320680496 86837.84689779364 86733.682901735 92805.58896615058 88364.88561144778 82440.40640052948 89611.89325027604 97959.83926259799 1.127424155508474 0.8901568917973551 0.9907697270371262 0.8864637544474735 0.8854004207707061 0.9473840470212433 0.9020521703243173 0.8415735164645786 0.9147819547769586 1.0 16.57990278620713 -4.757647544585555 24.99809064029009 0.9134184638186216 1.1274244615048066 0.6422490537868037 0.046881409852962005 67.27032740899052 443423.32063321024 0.011382945774472858 0.08304195247772991 1.747239564952183e-05 4.757647544585555 0.214005997686185 GPTTGEGALDLSDVHS(ph)PPKS(ph)PEGK ddPTM_PC-9_AZD4547_30min_R2 1 GPTTGEGALDLSDVHSPPKSPEGK 24 1 O95684;O95684-2 O95684 FGFR1OP FGFR1 oncogene partner 2 GPT(0.001)TGEGALDLS(0.008)DVHS(0.991)PPKS(1)PEGK 60.747 0.0017264 5769800.0 3676.3 8965.4 8601.8 11368.0 11290.0 14271.0 11450.0 10600.0 12016.0 12277.0 True False 4845.286928209684 11863.290222047437 8487.73451168372 8747.283233849188 9722.578379585537 13378.632113997834 12469.027818410872 8962.01356376789 12651.141228849812 11847.185966827974 0.4089820942944974 1.0013593316813423 0.716434648316428 0.7383426965982902 0.8206656337470078 1.1292666588891147 1.0524885701401203 0.7564677037113672 1.0678604408061887 1.0 13.532256799532037 -6.569981108343535 6.601497381542933 0.989023343705798 0.7415229189596858 0.4058749288114697 0.1621595383207633 0.22493001746575356 23.316180249706708 0.05229004932003579 0.05253905488769963 2.691651887286108e-07 6.569981108343535 -0.24750042474611222 GPTTGEGALDLSDVHSPPKS(ph)PEGK ddPTM_PC-9_AZD4547_30min_R2 2 GPTTGEGALDLSDVHSPPKSPEGK 24 1 O95684;O95684-2 O95684 FGFR1OP FGFR1 oncogene partner 1 GPTTGEGALDLS(0.001)DVHS(0.166)PPKS(0.833)PEGK;GPTTGEGALDLSDVHS(0.023)PPKS(0.977)PEGK 114.9 8.975299999999999e-09 12314600.0 81243.0 75079.0 91979.0 118014.0 103321.0 99740.0 101233.0 101776.0 85942.0 111624.0 True False 107076.58404062207 99346.81850013384 90759.29836198903 90807.69559812434 88976.66260027955 93503.24203280397 110242.54088569338 86048.85777981521 90484.71866592955 107716.07773570139 0.9940631546513565 0.9223025994679934 0.8425789377949824 0.8430282415308097 0.8260295442487056 0.8680527921024856 1.0234548379694168 0.7988487845885908 0.8400298318320527 1.0 16.716874077507534 -5.529217478175676 0.0026441092806192366 1.7709485168240788 1.139478463394383e-07 0.008672560923289163 0.07793908398368121 879389.8507466053 473.2874205010213 156182.63540694615 160827.9075710882 2.9565315771144346e-06 5.529217478175676 -1.7709484028762326 GPTTGEGALDLSDVHSPPKS(ph)PEGK ddPTM_PC-9_Lapatinib_30min_R1 1 GPTTGEGALDLSDVHSPPKSPEGK 24 1 O95684;O95684-2 O95684 FGFR1OP FGFR1 oncogene partner 1 GPTTGEGALDLS(0.001)DVHS(0.015)PPKS(0.985)PEGK 56.882 0.0028395 2990100.0 17842.0 17659.0 17173.0 18658.0 22144.0 17455.0 13863.0 18754.0 19183.0 15653.0 True False 17587.569808177916 17618.111670465725 15761.102229697011 20030.17156126342 20841.533456779074 16708.49033959236 14580.75830782005 19625.379304842983 17022.408534054684 18358.60019368854 0.9580016789201774 0.9596653058833219 0.8585132887808888 1.091051134070099 1.1352463279822465 0.9101178828076736 0.7942195022490186 1.0690019444723213 0.9272171273661037 1.0 14.164168439901772 -4.654368563023431 0.00223787942261745 1.5630779235596433 0.37074327892408704 0.0019250773511564345 0.10072714332436024 3636916.8826319836 1225.8445506649796 321080.20796645404 332113.8243773668 2.216314751007999e-05 4.654368563023431 -1.1923346446355563 GPVEGYEENEEFLR ddPTM_PC-9_AZD4547_30min_R2 2 GPVEGYEENEEFLR 14 0 F5GYQ2;F5GX77;Q9UI30-2;Q9UI30 F5GYQ2 TRMT112 Multifunctional methyltransferase subunit TRM112-like protein 0 ; 137.59 0.00033892 5080800.0 9684.3 7115.9 8692.400000000001 11436.0 11292.8 10009.4 9221.8 10547.7 7895.700000000001 8914.5 False True 12763.705954046465 9415.975515991186 8577.13309648674 8799.606884438721 9724.989647917057 9383.51063568425 10042.522335006228 8917.795327033453 8313.050582608976 8602.406068362621 1.4837367420945178 1.0945746389048825 0.9970621042909344 1.0229239139037336 1.130496464667368 1.090800708675486 1.1674085430516905 1.0366629122322824 0.9663634239706704 1.0 13.070524518593563 -4.76376349085428 4.731088425983827 1.0592094752449397 1.514371786073691 0.8229740592836976 0.059686313380166035 0.07858298645451964 4.20981719063436 0.01577804339361024 0.12043048342383894 1.7228065297380416e-05 4.76376349085428 0.45516231082875125 GPVEGYEENEEFLR ddPTM_PC-9_Lapatinib_30min_R1 2 GPVEGYEENEEFLR 14 0 F5GYQ2;F5GX77;Q9UI30-2;Q9UI30 F5GYQ2 TRMT112 Multifunctional methyltransferase subunit TRM112-like protein 0 ; 168.82 0.00039189 5865800.0 8924.6 11782.7 12478.4 12056.5 12713.8 12667.9 10305.9 8288.3 11982.3 11265.3 False True 8797.333567428805 11755.417882076932 11452.47412001696 12943.175229304983 11965.999280292528 12126.123447317214 10839.48907484401 8673.404675926748 10632.727194787223 13212.492094931304 0.6658345378162018 0.8897199557520759 0.8667913696925095 0.9796164975016607 0.9056580086721894 0.917777158176628 0.8203970149584691 0.6564548620811753 0.804748045894101 1.0 13.689614987989437 -7.514023037103693 24.78488029555713 0.7860460772899777 0.8773396984009907 0.018927546636510195 0.10991658527308035 822.5810522595159 2302216.7529380154 0.04842096324346825 0.02981310211104651 3.061801016480146e-08 7.514023037103693 0.09129362111101302 GPVGT(ph)VSEAQLAR ddPTM_PC-9_Lapatinib_30min_R1 1 GPVGTVSEAQLAR 13 0 Q9NZM1-5;Q9NZM1-2;Q9NZM1-6;Q9NZM1;Q9NZM1-3;Q9NZM1-8;Q9NZM1-7 Q9NZM1-5 MYOF Myoferlin 1 GPVGT(0.76)VS(0.24)EAQLAR 187.74 7.954199999999999e-05 9688000.0 17080.0 13918.0 8504.1 8246.7 7832.3 9221.9 4908.0 1719.9 9548.0 7655.4 True False 16836.436067911603 13885.773726119376 7804.925724775313 8853.189828184746 7371.6195128942645 8827.500834298866 5162.1122249715645 1799.8128328036403 8472.603695102647 8978.62568982069 1.8751685001190688 1.5465366533613325 0.8692784390849445 0.9860295031812993 0.82101869122929 0.9831683755685284 0.5749334478687523 0.20045526954577653 0.943641486770995 1.0 13.132278920918706 -4.142961419935615 0.6255222922766336 0.6789785538969012 4.058320403185736 0.7103195699309384 0.23665526138970802 3.701681922456452 0.6128506286317678 0.11019044194716167 10.73236062121609 7.195128922875327e-05 4.142961419935615 3.3793418492888345 GPVGTVS(ph)EAQLAR ddPTM_PC-9_AZD4547_30min_R2 3 GPVGTVSEAQLAR 13 0 Q9NZM1-5;Q9NZM1-2;Q9NZM1-6;Q9NZM1;Q9NZM1-3;Q9NZM1-8;Q9NZM1-7 Q9NZM1-5 MYOF Myoferlin 1 GPVGT(0.056)VS(0.944)EAQLAR;GPVGT(0.002)VS(0.998)EAQLAR;GPVGT(0.019)VS(0.981)EAQLAR 128.35 0.00010593 25543500.0 23662.5 32001.8 38719.9 48076.5 33271.6 26184.6 38676.600000000006 32973.6 29561.5 32114.899999999998 True False 31186.682789424573 42345.75602069265 38206.448826866756 36993.20569952063 28652.412649620746 24547.27282266047 42118.742473497805 27878.287777948757 31124.060539001624 30990.567126014783 1.0063282373185471 1.3664079088486847 1.2328412278326673 1.193692440318944 0.9245527044766053 0.7920885320635019 1.3590826622253571 0.8995733335433721 1.004307549856833 1.0 14.91954153597092 -6.187412298069937 6.512712840742656 0.9997601332974209 1.2160942357979867 0.2778696688842439 0.1597333331589514 0.3224691205895815 23.418238597412113 0.04719340194830445 0.0610868330533921 6.495127816959479e-07 6.187412298069937 0.21633410250056584 GPVGTVS(ph)EAQLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GPVGTVSEAQLAR 13 0 Q9NZM1-5;Q9NZM1-2;Q9NZM1-6;Q9NZM1;Q9NZM1-3;Q9NZM1-8;Q9NZM1-7 Q9NZM1-5 MYOF Myoferlin 1 GPVGT(0.005)VS(0.995)EAQLAR;GPVGT(0.235)VS(0.765)EAQLAR;GPVGT(0.067)VS(0.933)EAQLAR 130.61 7.8388e-05 22296100.0 29063.0 23989.8 17488.4 23833.0 27588.300000000003 22673.6 23314.9 19755.7 19254.5 15034.9 True False 33982.791879584736 26371.348800935117 17905.38978112634 22497.71427762853 22182.570659268637 21484.556501408402 21106.343886741524 19237.133807894403 19536.06063656478 17760.60835379709 1.913379947501599 1.4848223819595183 1.0081518281606776 1.2667198008912053 1.2489758355898974 1.2096745828424935 1.188379556955274 1.0831348467735138 1.0999657358239145 1.0 14.116393378690994 -4.9168941697021165 2.804336492797243 1.1546516442431207 1.9526133518235602 0.8729722646655705 0.09240991911087416 0.10727583048910909 1.4255816751568071 0.02426119990396789 0.17237368244674228 1.2108931720043422e-05 4.9168941697021165 0.7979617075804395 GPVGTVS(ph)EAQLAR ddPTM_PC-9_Lapatinib_30min_R1 2 GPVGTVSEAQLAR 13 0 Q9NZM1-5;Q9NZM1-2;Q9NZM1-6;Q9NZM1;Q9NZM1-3;Q9NZM1-8;Q9NZM1-7 Q9NZM1-5 MYOF Myoferlin 1 GPVGT(0.006)VS(0.994)EAQLAR;GPVGT(0.011)VS(0.989)EAQLAR 143.94 8.8866e-05 15020100.0 32038.0 30773.0 30359.0 9373.8 24293.9 15976.4 10559.599999999999 9872.2 22489.4 7890.200000000001 True False 31581.13224495036 30701.747009187493 27863.000209128953 10063.180522080118 22864.980565645088 15293.126614807405 11106.324419480377 10330.898452237972 19956.406948119118 9254.01055696936 3.4126968032434375 3.3176693305223712 3.0109107870149154 1.0874399224130296 2.4708185088923487 1.6525944638446384 1.2001633617238534 1.1163698580889978 2.1565143918157292 1.0 13.17586302939182 -5.664922668155952 5.374006891276793 1.5648255433409521 3.311552426088967 0.7488671047445143 0.45808999694718006 0.10175699202097058 4.566597310120153 0.12616234173711735 0.22118830180355908 2.163103658490909e-06 5.664922668155952 1.746726882748015 GPVS(ph)GTEPEPVYSMEAADYR ddPTM_PC-9_AZD4547_30min_R2 1 GPVSGTEPEPVYSMEAADYR 20 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 GPVS(0.494)GT(0.198)EPEPVY(0.241)S(0.067)MEAADYR 95.9 0.00045268 7994500.0 21245.0 19836.0 26371.0 39311.0 35666.0 36200.0 24398.0 34092.0 26336.0 32257.0 True False 28000.46807654836 26247.599085878282 26021.30330949469 30248.45629889564 30714.39153997324 33936.40827739624 26569.374734811223 28823.86475622404 27728.0671939904 31127.692248266663 0.8995356242031581 0.8432234190872236 0.8359535008877402 0.9717538986713676 0.9867224108682057 1.0902320675342059 0.8535606983935897 0.9259878479372042 0.8907845455692086 1.0 14.92591100147715 -5.764589736015715 24.999701640183638 0.9589011513322728 0.8579360957192382 0.35043694437181183 0.06255088693076608 94.80825560507513 752362.3284254337 0.01847286639573112 0.028759718513229195 1.7195320065512874e-06 5.764589736015715 -0.1009650556130346 GPVS(ph)GTEPEPVYSMEAADYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GPVSGTEPEPVYSMEAADYR 20 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 GPVS(0.758)GT(0.238)EPEPVY(0.002)S(0.002)MEAADYR;GPVS(0.865)GT(0.135)EPEPVYSMEAADYR 92.096 0.00056303 9848100.0 37010.0 39999.0 46060.0 51162.0 82774.0 91557.0 85193.0 82169.0 92425.0 77704.0 True False 43275.06201918012 43969.8363758182 47158.24508352276 48295.55900944198 66555.02889813085 86755.58974311313 77122.90229609274 80012.15081525191 93776.5407740787 91791.12009547425 0.4714515083176743 0.47902058859379937 0.5137560695900898 0.5261463086974922 0.7250704515742404 0.9451414216634078 0.8402000347732468 0.8716763749263464 1.0216297685063584 1.0 16.486066973124558 -6.453901928333794 1.8829197825623925 0.9276512656378427 0.48533695818803757 0.9378529009015985 0.053102652734508766 0.07985782420041027 0.5650011440104459 0.019769755361826045 0.022562893075267387 3.5163983829364084e-07 6.453901928333794 -0.44231430744980516 GPVS(ph)PSVSFQPLAR ddPTM_PC-9_AZD4547_30min_R2 2 GPVSPSVSFQPLAR 14 0 Q7Z434-4;Q7Z434 Q7Z434-4 MAVS Mitochondrial antiviral-signaling protein 1 GPVS(0.989)PS(0.01)VS(0.001)FQPLAR;GPVS(0.983)PS(0.015)VS(0.001)FQPLAR 154.13 2.9768e-05 75863000.0 19214.6 22094.0 31656.0 36623.0 27201.0 23909.0 31129.0 40181.0 37003.0 27141.0 True False 25324.443111491913 29235.45342828165 31236.220756337058 28180.133169709603 23424.610673437226 22413.966450394102 33899.42069513642 33971.949717524294 38958.90303687829 26190.801851077442 0.9669212594363586 1.1162488874726435 1.1926408719346657 1.0759553422588444 0.8943831046728178 0.855795350514327 1.294325423402104 1.2970946789140307 1.4875032562348065 1.0 14.676772609106772 -7.289589440637109 23.297558491777597 1.29448889433664 1.026593772743828 0.41457193682019944 0.14568592918413645 312.71545721922405 258807.53785562582 0.0626252214553584 0.042236488768123394 5.133464456475784e-08 7.289589440637109 -0.26789512159281204 GPVS(ph)PSVSFQPLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GPVSPSVSFQPLAR 14 0 Q7Z434-4;Q7Z434 Q7Z434-4 MAVS Mitochondrial antiviral-signaling protein 1 GPVS(0.972)PS(0.026)VS(0.002)FQPLAR 137.73 7.5743e-05 6508400.0 12220.0 10763.0 10939.0 8981.1 19012.0 13922.0 12620.0 17234.0 14805.0 13466.0 True False 14288.6046439984 11831.479509811024 11199.827246388515 8477.91808411906 15286.73507878395 13191.905811719702 11424.542239112237 16781.625760932384 15021.495116691765 15907.279203202657 0.8982431540600379 0.7437776981640556 0.704069319669301 0.5329584007309167 0.9609899269075649 0.8292999477285681 0.7181958707817301 1.0549651858473503 0.9443158018919694 1.0 13.95739947632969 -7.760432789038137 24.999961041911554 0.9997304014153408 0.7666806897361044 0.4676179643955166 0.11248525868673297 24.444636404505843 607168.160742528 0.058631151052838386 0.03134461118516976 1.7360699144552842e-08 7.760432789038137 -0.23304971167923638 GPVS(ph)PSVSFQPLAR ddPTM_PC-9_Lapatinib_30min_R1 1 GPVSPSVSFQPLAR 14 0 Q7Z434-4;Q7Z434 Q7Z434-4 MAVS Mitochondrial antiviral-signaling protein 1 GPVS(0.776)PS(0.195)VS(0.03)FQPLAR 98.943 0.0023283 29256000.0 15859.0 17931.0 10020.0 9116.3 10154.0 12567.0 9484.7 9977.2 14516.0 9479.5 True False 15632.847751815596 17889.481871177344 9196.194278318535 9786.743113085304 9556.761683532088 12029.538705107829 9975.771357006477 10440.77713555932 12881.055219743408 11118.018944360228 1.4060821293838124 1.6090530121152595 0.8271432459632059 0.8802596183783054 0.8595741499774913 1.0819858074814652 0.8972615901204978 0.939086107678882 1.1585746781154302 1.0 13.440612125006316 -5.26013054803362 24.99999908446281 0.9496365249948598 1.5075676081079818 0.8089751587112067 0.10728003596252553 43.200974561633494 825158.8943021036 0.027583876958378543 0.06525494889703874 5.493757078196623e-06 5.26013054803362 0.557931083113122 GPVSGS(ph)PDSMNASR ddPTM_PC-9_AZD4547_30min_R2 2 GPVSGSPDSMNASR 14 0 A0A499FJS7;O14920-4;O14920-2;O14920 A0A499FJS7 IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta 1 GPVS(0.028)GS(0.512)PDS(0.459)MNASR;GPVS(0.021)GS(0.89)PDS(0.089)MNASR 86.738 0.005621500000000001 9642500.0 30555.0 29847.0 36610.0 43438.0 37517.0 38006.0 33750.0 40272.0 29607.0 33309.0 True False 40270.85441651847 39494.45906010328 36124.52747945093 33424.04021041 32308.41214055897 35629.47881189835 36753.684617586645 34048.88775849628 31171.96557611155 32142.862048470528 1.2528708350796878 1.2287163165665445 1.1238740167249626 1.0398588700660039 1.0051504465233618 1.1084725049738913 1.14344779136852 1.0592985685951526 0.9697943365810147 1.0 14.972210774004298 -5.379730867227201 2.396042604523232 1.0541193481790212 1.2499700439482608 0.71228454855447 0.048932547368802676 0.17926128957164425 1.9605165151273478 0.014740041551045125 0.041622284742614195 4.171277979518828e-06 5.379730867227201 0.19585069576923964 GPVSGS(ph)PDSMNASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GPVSGSPDSMNASR 14 0 A0A499FJS7;O14920-4;O14920-2;O14920 A0A499FJS7 IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta 1 GPVS(0.001)GS(0.616)PDS(0.383)MNAS(0.001)R;GPVS(0.006)GS(0.709)PDS(0.282)MNAS(0.003)R;GPVSGS(0.579)PDS(0.42)MNASR 106.3 0.00078291 28323800.0 48132.0 53798.0 63287.0 54301.0 62365.0 55529.0 57528.0 45088.0 45321.0 41017.0 True False 56279.79694966703 59138.70990140418 64796.00209728403 51258.69101621725 50145.025940898435 52616.9614867823 52078.53137334776 43904.48777468487 45983.733886091664 48453.05740960665 1.1615324183548548 1.2205361862196733 1.337294395057867 1.0579041603689252 1.03491974751951 1.085936869617439 1.0748244622231475 0.9061241977679628 0.9490367862106179 1.0 15.564300082764818 -6.353689389966096 0.7980148352728468 0.969238777966092 1.2421915791512341 0.647022125083005 0.0724937663349482 0.44087864714025243 0.6143438088871862 0.04433736673379693 0.06779202443012582 4.4290502746035113e-07 6.353689389966096 0.2729528011851421 GPVSGS(ph)PDSMNASR ddPTM_PC-9_Lapatinib_30min_R1 2 GPVSGSPDSMNASR 14 0 A0A499FJS7;O14920-4;O14920-2;O14920 A0A499FJS7 IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta 1 GPVS(0.002)GS(0.844)PDS(0.154)MNASR;GPVS(0.003)GS(0.704)PDS(0.293)MNAS(0.001)R 153.0 0.00022776 7395200.0 30460.0 36009.0 42864.0 34708.0 41561.0 39960.0 38353.0 37783.0 41531.0 29800.0 True False 30025.634814320107 35925.62337288636 39339.88737982489 37260.542102493884 39116.46369206986 38251.003951309685 40338.730677329746 39538.53611362285 36853.341439181815 34950.890293995944 0.8590806861214083 1.0278886480627893 1.1255761169146214 1.0660827746895678 1.1191836134368658 1.0944214476242011 1.1541545962924828 1.1312597699525553 1.0544321225921014 1.0 15.093041584974879 -4.797791536708744 2.519542556253911 1.0999384202438163 0.811387839564658 0.7287512920001252 0.04291456082335438 0.23171571565988544 1.9356025528648113 0.010612023778442035 0.14381031740616315 1.5929731778075743e-05 4.797791536708744 -0.2885505806791583 GPVSGSPDS(ph)MNASR ddPTM_PC-9_AZD4547_30min_R2 1 GPVSGSPDSMNASR 14 0 A0A499FJS7;O14920-4;O14920-2;O14920 A0A499FJS7 IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta 1 GPVS(0.001)GS(0.014)PDS(0.902)MNAS(0.083)R 79.639 0.011041 7593000.0 8801.6 8769.0 13610.0 15507.0 12767.0 12698.0 10120.0 17813.0 10744.0 13077.0 True False 11600.325715347044 11603.407762858777 13429.522507383981 11932.10073076173 10994.522424461346 11903.99205266235 11020.66039496227 15060.410152018634 11311.905905689282 12619.178210329019 0.9192615812218242 0.9195058164216418 1.0642152986152205 0.9455529141347013 0.8712550247893429 0.943325457034811 0.8733263142239853 1.193454114126974 0.8964059083047332 1.0 13.623330341336919 GPVSGSPDS(ph)MNASR ddPTM_PC-9_Lapatinib_30min_R1 1 GPVSGSPDSMNASR 14 0 A0A499FJS7;O14920-4;O14920-2;O14920 A0A499FJS7 IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta 1 GPVSGS(0.1)PDS(0.899)MNASR 91.307 0.0040423 5232400.0 9412.5 11457.0 17198.0 11140.0 12216.0 13451.0 11919.0 10708.0 16591.0 9057.7 True False 9278.276023958904 11430.47202041599 15784.046826199812 11959.272761950599 11497.478897580067 12875.73208581247 12536.107499885093 11205.53277147588 14722.346869024723 10623.311376373393 0.8733883151155776 1.0759801360842862 1.4857934844406493 1.1257575287257822 1.0822876681512748 1.2120262345362989 1.180056486696401 1.0548060180554784 1.3858528991033554 1.0 13.374945916089969 -4.890511714322212 4.308799038395376 1.1920703122449008 0.880212388227032 0.31971409903537673 0.14089367011346182 0.24258144620854866 7.377294285154818 0.03421516807261788 0.17294968979389408 1.2867325452367988e-05 4.890511714322212 -0.3118579240178688 GPVSGT(ph)EPEPVYSMEAADYR ddPTM_PC-9_AZD4547_30min_R2 2 GPVSGTEPEPVYSMEAADYR 20 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 GPVS(0.124)GT(0.872)EPEPVY(0.002)S(0.002)MEAADYR;GPVS(0.231)GT(0.764)EPEPVY(0.003)S(0.001)MEAADYR 105.0 0.00057245 7443200.0 45859.4 42202.8 63417.5 83909.1 70877.3 78762.2 49899.9 64747.6 54582.5 65568.2 True False 60441.735265222924 55844.029779265155 62576.54251374157 64565.15337767191 61037.21032625318 73837.18718303692 54340.89443108476 54742.346171831894 57467.61951761775 63272.67727540676 0.9552580650592419 0.8825931220863793 0.9889978614523435 1.020427080975875 0.964669316276546 1.1669679609359038 0.8588366538459459 0.865181442118453 0.9082533250091291 1.0 15.949295021873427 GPVSGTEPEPVYS(ph)MEAADYR ddPTM_PC-9_AZD4547_30min_R2 3 GPVSGTEPEPVYSMEAADYR 20 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 GPVSGTEPEPVY(0.025)S(0.975)MEAADYR;GPVSGTEPEPVYS(1)MEAADYR;GPVSGTEPEPVY(0.017)S(0.983)MEAADY(0.001)R 120.39 1.0267999999999999e-05 6908500.0 64146.0 56184.0 73241.0 107668.0 106684.0 90691.0 75089.0 101149.0 80984.0 95281.0 True False 84543.09368031411 74344.37926199762 72269.77648518069 82846.80605401771 91872.76809988522 85020.07743329654 81771.7755333321 85518.74622278867 85264.64890788715 91945.2411912794 0.9194939573265554 0.8085723447865494 0.7860088847320915 0.9010450674838771 0.9992117798544525 0.9246816510756003 0.8893529939544906 0.9301051921205873 0.9273416198942347 1.0 16.488487286569395 -5.9673131952063105 7.603319066463824 0.9389445529708702 0.8359745240593972 0.5264844421540412 0.04523712306856199 0.16636635038621192 31.033856350375135 0.012924393222732755 0.019087633508816638 1.0781689110041993e-06 5.9673131952063105 -0.102970028911473 GPVSGTEPEPVYS(ph)MEAADYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GPVSGTEPEPVYSMEAADYR 20 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 GPVSGTEPEPVY(0.024)S(0.976)MEAADYR;GPVSGTEPEPVY(0.424)S(0.576)MEAADYR;GPVSGTEPEPVY(0.158)S(0.836)MEAADY(0.006)R;GPVSGTEPEPVYS(1)MEAADYR 132.87 1.213e-06 12623900.0 42229.2 42042.2 44368.2 59738.0 84065.0 85371.0 96096.0 94763.0 97799.0 90129.0 True False 49377.769495281245 46215.87176877983 45426.106155335525 56391.073533209084 67593.06671565192 80893.99447294374 86993.09120520833 92275.57165969793 99229.12535746982 106468.67423922877 0.46377744297193313 0.434079527138053 0.42666170570759404 0.5296494385428497 0.634863420613037 0.7597915072294387 0.817076870984042 0.8666922202145602 0.9320030146567608 1.0 16.70006949016868 -6.809730775166179 0.6575496354372696 0.9709559839942322 0.40362655934890923 0.9839356027236884 0.026022994008424484 0.09168075744498734 0.08637359151809153 0.02193576205390064 0.022168507079706943 1.5497770482676428e-07 6.809730775166179 -0.567329424645323 down GPVSGTEPEPVYS(ph)MEAADYR ddPTM_PC-9_Lapatinib_30min_R1 4 GPVSGTEPEPVYSMEAADYR 20 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 GPVSGTEPEPVY(0.299)S(0.649)MEAADY(0.053)R;GPVSGTEPEPVY(0.426)S(0.572)MEAADY(0.002)R;GPVSGTEPEPVY(0.346)S(0.654)MEAADYR;GPVS(0.204)GT(0.204)EPEPVY(0.063)S(0.53)MEAADYR 89.23100000000001 0.00061379 14041700.0 51788.5 41777.5 59085.8 63116.7 84429.8 93829.3 92704.2 86947.2 124086.0 109997.5 True False 51049.98649315225 41680.766765551976 54227.99360178375 67758.51266913899 79463.80515937346 89816.4395657814 97503.96987086571 90987.08432835915 110110.12799649204 129010.42131254416 0.39570436228153355 0.3230806189259317 0.4203380862574624 0.5252173582549999 0.6159487299623825 0.6961952271141697 0.7557836714186829 0.7052692596664836 0.8534979335486104 1.0 16.97712808402848 -6.205909714956596 0.26110635136953586 1.0239786567366955 0.07184584737491712 0.9553279812815324 0.043157381917766045 0.8594672942849387 0.09461055357515503 0.07251486540511473 0.2613900343044603 6.224296679982371e-07 6.205909714956596 -0.9521328093617785 down GQAAVQQLQAEGLSPR ddPTM_PC-9_Lapatinib_30min_R1 1 GQAAVQQLQAEGLSPR 16 0 O75828;E9PQ63;A8MTM1;P16152-2;P16152 O75828;P16152 CBR3;CBR1 Carbonyl reductase [NADPH] 3;Carbonyl reductase [NADPH] 1 0 159.12 0.00023567 4179500.0 14362.0 11686.0 14241.0 15185.0 12032.0 16355.0 14909.0 14868.0 19466.0 14378.0 False True 14157.195246331761 11658.941784985698 13070.15995184971 16301.755555675049 11324.30141582215 15655.534775367105 15680.915069702745 15558.821558302538 17273.53409393256 16863.218142519254 0.8395310507568853 0.6913829665518357 0.7750691381317275 0.9667048968886596 0.6715385711146576 0.9283835767914861 0.9298886450483952 0.9226484189914033 1.0243320075649576 1.0 14.041592263113792 -7.284346307643542 0.7581549478845723 1.0111371683172052 0.7801481998900685 0.4992767096626788 0.08397245240990904 0.5703293286293373 0.6415988001853649 0.06948495430923113 0.04264603792487614 5.1958151553685406e-08 7.284346307643542 -0.2309889684271368 GQAGLPGGLVS(ph)PGSGDR ddPTM_PC-9_AZD4547_30min_R2 1 GQAGLPGGLVSPGSGDR 17 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 GQAGLPGGLVS(0.921)PGS(0.079)GDR 61.477 0.032039 21465000.0 44023.0 58422.0 65827.0 107970.0 95318.0 79548.0 59462.0 75696.0 72529.0 78836.0 True False 58021.398264715885 77305.76899552239 64954.09096940226 83079.18461987135 82084.74100844402 74573.85098481545 64754.00280684253 63998.92252103532 76362.7348691119 76075.97563581087 0.7626770183332852 1.0161653314260306 0.8538055598570167 1.0920554606829636 1.0789837438483625 0.9802549406899971 0.8511754501425177 0.8412501053868762 1.0037693796353502 1.0 16.215153310240296 -4.752237064023768 24.99030660934931 0.9640595370451914 0.7626766251195702 0.3349297300148233 0.0868431630724442 482.70961965461225 1310777.3891983158 0.02323210036537933 0.2837254232277445 1.7691429901527768e-05 4.752237064023768 -0.2013829119256212 GQAGLPGGLVS(ph)PGSGDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GQAGLPGGLVSPGSGDR 17 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 GQAGLPGGLVS(0.838)PGS(0.162)GDR;GQAGLPGGLVS(0.985)PGS(0.015)GDR;GQAGLPGGLVS(0.756)PGS(0.244)GDR 114.06 0.00017197 22609200.0 52545.9 56208.0 60413.0 76160.0 82990.0 91440.0 93631.0 98407.0 82590.0 69218.0 True False 61440.88304116821 61787.9587742691 61853.47503757834 71893.00211405157 66728.7052486997 86644.72542907986 84761.5938502629 95823.92052083515 83797.72250507065 81766.67547061361 0.7514171597113501 0.7556618685869805 0.7564631273263405 0.8792457526280304 0.8160868087718882 1.059658166733456 1.0366276158644316 1.1719189996329693 1.0248395452397594 1.0 16.31922536294843 -6.664373801727528 1.5264205634453443 1.079993305583274 0.7699837992767647 0.8335462599551452 0.05888627152796432 0.138842618299162 0.6708966552657997 0.02418972783803644 0.023771493777827814 2.165839142312005e-07 6.664373801727528 -0.31000950630650925 GQAGLPGGLVS(ph)PGSGDR ddPTM_PC-9_Lapatinib_30min_R1 2 GQAGLPGGLVSPGSGDR 17 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 GQAGLPGGLVS(0.927)PGS(0.073)GDR;GQAGLPGGLVS(0.634)PGS(0.366)GDR 102.84 0.00092395 18272700.0 96030.0 76315.0 92149.0 67517.0 101607.0 95225.0 110534.0 91774.0 109608.0 92313.0 True False 94660.59459025499 76138.29730627954 84572.86492542649 72482.4254101096 95630.67602704803 91152.44873031702 116256.90967298418 96038.15507745885 97262.79281659098 108269.1790506595 0.8743078632374499 0.7032315010964864 0.7811351823943781 0.6694649949843514 0.883267767111286 0.8419057900833117 1.0737765880591668 0.8870313409555114 0.898342387643684 1.0 16.724263084334858 -6.688296703418848 2.004642089029984 0.9510877948380269 0.7576068441468771 0.5512761432884243 0.07802138093141639 0.24079994060017287 1.9887810283278258 0.02951663292778333 0.028507507590432475 2.0497613344328863e-07 6.688296703418848 -0.1934809506911498 GQAGLPGGLVSPGS(ph)GDR ddPTM_PC-9_AZD4547_30min_R2 2 GQAGLPGGLVSPGSGDR 17 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 GQAGLPGGLVS(0.145)PGS(0.855)GDR;GQAGLPGGLVS(0.338)PGS(0.662)GDR 134.4 3.0112e-05 22628000.0 82511.0 73844.0 94183.0 159169.0 114404.0 119465.0 92582.0 102789.0 100364.0 118405.0 True False 108747.78166458354 97712.62890187518 92934.07188192091 122475.0461865361 98520.9793567849 111994.83466461692 100821.61864490065 86905.32190623948 105669.0361428332 114259.67698967733 0.9517599255458095 0.8551803354975608 0.8133584334420703 1.071900861382629 0.8622550137760819 0.9801781137079092 0.8823901948717155 0.76059485022079 0.9248147634128158 1.0 16.801956831000723 -9.811475227738846 12.166724737284271 0.9999999999999973 0.898033978778556 0.11287047527282379 0.08366707754080516 0.0 0.0 0.08080666255785937 0.019598494410570474 1.543564466099966e-10 9.811475227738846 -0.10196602122144138 GQAGLPGGLVSPGS(ph)GDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GQAGLPGGLVSPGSGDR 17 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 GQAGLPGGLVS(0.439)PGS(0.561)GDR 109.77 0.00043626 8792400.0 20860.0 20004.0 28585.0 27770.0 35818.0 30033.0 44151.0 37620.0 30278.0 28819.0 True False 24391.185996219847 21989.864918169642 29266.574809216185 26214.136931554734 28799.720021664383 28458.016609925122 39968.69765444092 36632.514861684824 30720.75846965169 34043.65656892154 0.7164678666887553 0.645931346230422 0.8596777713923258 0.7700153148497457 0.8459643564832472 0.8359271440866446 1.17404244087365 1.076045247593252 0.9023930319428928 1.0 15.055098382217672 -7.085764310743908 4.778277519789685 1.0437704913266863 0.771783235850224 0.6931282664323047 0.08525721658529829 0.1345370200308928 5.298577002392311 0.034871367558114236 0.027074491538594748 8.207968654822498e-08 7.085764310743908 -0.2719872554764623 GQDVVQEWQET(ph)SPTREEPAGEQK ddPTM_PC-9_AZD4547_30min_R2 1 GQDVVQEWQETSPTREEPAGEQK 23 1 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 GQDVVQEWQET(0.443)S(0.443)PT(0.113)REEPAGEQK 60.951 0.0033814 11941000.0 27735.0 28526.0 34043.0 38429.0 35351.0 35223.0 30936.0 36213.0 30803.0 33773.0 True False 36554.15307616231 37746.47164366626 33591.567576698966 29569.78777213146 30443.12385267744 33020.500241843285 33689.24406902697 30617.112941955358 32431.18369442914 32590.617549701154 1.121615846045774 1.158200564506099 1.0307128278705167 0.9073098331762851 0.934106995863188 1.0131903819093502 1.0337099018651732 0.9394456209755409 0.9951079829945267 1.0 14.992169069074539 -5.418355635194437 4.021178075356378 0.9740966116111759 1.1383392246757469 0.7451922611676404 0.03808233450633874 0.11342090370849849 3.170910517062598 0.01085567574495656 0.023936145150043685 3.816316322262775e-06 5.418355635194437 0.164242613064571 GQEADLEAGGEEVPEANGS(ph)AGKR ddPTM_PC-9_AZD4547_30min_R2 1 GQEADLEAGGEEVPEANGSAGKR 23 1 Q9NX58 Q9NX58 LYAR Cell growth-regulating nucleolar protein 1 GQEADLEAGGEEVPEANGS(1)AGKR 96.708 0.0015325 0.0 9313.0 7401.0 10873.0 13183.0 9402.4 8500.4 7437.6 12276.0 10106.0 7056.7 True False 12274.340277566249 9793.228515556819 10728.81691570801 10143.863025319657 8097.039057237827 7968.868644231453 8099.531991459628 10379.026274416477 10640.182528192086 6809.647080892313 1.8024928651600343 1.4381403910103292 1.5755320045605274 1.489631240036369 1.1890541405527317 1.170232252797929 1.1894202291608764 1.5241650780316862 1.5625160014603625 1.0 12.73336431522835 -6.064359822309426 4.1642330962723 1.2902838818815672 1.5834287058527878 0.4172055127167823 0.17828816154475532 0.26049065965310675 8.897000582200343 0.05569733209455682 0.075653839074619 8.622638476114517e-07 6.064359822309426 0.29314482397122066 GQEEISGALPVAS(ph)PASSR ddPTM_PC-9_AZD4547_30min_R2 3 GQEEISGALPVASPASSR 18 0 H0Y9D5;H0Y8S9;Q9UBK8;Q9UBK8-1 H0Y9D5 MTRR Methionine synthase reductase 1 GQEEISGALPVAS(0.991)PAS(0.008)S(0.001)R;GQEEISGALPVAS(0.976)PAS(0.02)S(0.005)R;GQEEISGALPVAS(0.654)PAS(0.278)S(0.067)R 94.31299999999999 0.00096565 17401200.0 44904.0 46163.1 59107.2 69948.3 58648.6 58446.6 53937.6 75566.8 63321.1 57917.0 True False 59182.53793877746 61084.419306377706 58323.39990804162 53822.80012546215 50506.2542385262 54791.92486258746 58737.94190902339 63889.68741231468 66668.12407341231 55889.34345856279 1.0589234776510892 1.092952887372288 1.0435513516325965 0.9630243762903958 0.9036830836270657 0.9803644392997929 1.0509685438078655 1.1431461430511072 1.1928593171405042 1.0 15.770285607070482 -7.587468457899849 4.117528539373058 1.124946241338157 1.0063567294019105 0.3208250434355815 0.06739534264080697 0.2533559637034799 8.634868325258022 0.03640152070572556 0.0203262845172025 2.5854226077722122e-08 7.587468457899849 -0.11858951193624656 GQEEISGALPVAS(ph)PASSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GQEEISGALPVASPASSR 18 0 H0Y9D5;H0Y8S9;Q9UBK8;Q9UBK8-1 H0Y9D5 MTRR Methionine synthase reductase 1 GQEEISGALPVAS(1)PASSR;GQEEIS(0.001)GALPVAS(0.916)PAS(0.068)S(0.016)R;GQEEISGALPVAS(0.977)PAS(0.018)S(0.004)R 225.08 2.3814999999999996e-96 7774600.0 46173.0 48915.0 45987.0 53655.0 54255.0 51841.0 49783.0 46675.0 48674.0 34157.0 True False 53989.17694168072 53770.957932026984 47083.50448666871 50648.88430185705 43624.122222776285 49122.36669913525 45067.19384229196 45449.83070625041 49385.765167838894 40349.393713336765 1.3380418383792363 1.3326336032219974 1.166894968017973 1.2552576294378364 1.0811592990146248 1.2174251501305393 1.1169236931407922 1.1264067814537642 1.2239530913079202 1.0 15.30025937539863 -1.5228787452803376 0.23832402363112148 1.0817027821215712 2.675644390534005 0.5947357509792561 0.06557883878761277 35.24364350673374 0.4693471100222803 0.08718822219320481 22.16744126728853 0.029999999999999995 1.5228787452803376 1.5939416084124336 GQEEISGALPVASPASS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 GQEEISGALPVASPASSR 18 0 H0Y9D5;H0Y8S9;Q9UBK8;Q9UBK8-1 H0Y9D5 MTRR Methionine synthase reductase 1 GQEEISGALPVAS(0.291)PAS(0.177)S(0.533)R 114.56 0.00014004 4075900.0 12288.0 8581.0 12149.0 15820.0 9426.9 12762.0 14006.0 16418.0 13239.0 12983.0 True False 16195.328393722108 11354.640439399152 11987.89632198441 12172.94341656352 8118.137655138608 11963.990122545041 15252.506866782773 13880.975348107664 13938.78651204583 12528.469121717653 1.2926821494613483 0.9063070937945873 0.9568524458589933 0.9716225740192117 0.6479752295566669 0.9549442957724095 1.2174278212765115 1.107954628235104 1.1125690119540177 1.0 13.61292251923423 -7.16993664665936 7.851875012994635 1.118109565169919 0.9389367058663703 0.190195657326795 0.1537278829913959 0.45783344248447266 35.10186614089625 0.06003111956925195 0.046450972123089865 6.761816071754296e-08 7.16993664665936 -0.17917285930354876 GQES(ph)FKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GQESFKK 7 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 GQES(1)FKK 66.435 0.04069 0.0 28134.0 30429.0 25696.0 31536.0 35202.0 21554.0 29703.0 23835.0 25465.0 20449.0 True False 32896.530528171126 33449.79002174484 26308.690092622663 29769.140161091476 28304.420799671385 20423.670296351564 26889.316808902615 23209.35650527001 25837.377449953092 24156.241825805057 1.3618231993781915 1.3847265755558007 1.0891052624137187 1.2323580950945112 1.1717228616843458 0.8454821094949402 1.1131415641061324 0.960801629352645 1.0695942537862886 1.0 14.560108400395576 -5.358179882489019 0.6306697487733638 1.0011165639044008 1.499114288458846 0.6425872931379615 0.0968467610253944 1.1898340984027946 0.5800732014618881 0.05158081052464271 0.3885933097349339 4.3834909827901845e-06 5.358179882489019 0.49799772455444513 GQES(ph)PLKK ddPTM_PC-9_Lapatinib_30min_R1 1 GQESPLKK 8 1 A0A3B3ITL0;Q9Y2H2;A0A3B3IRJ9;Q9Y2H2-4 A0A3B3ITL0 INPP5F Phosphatidylinositide phosphatase SAC2 1 GQES(1)PLKK 74.16199999999999 0.041391000000000004 4313000.0 19895.0 16760.0 17836.0 18043.0 17437.0 17282.0 16685.0 16898.0 19803.0 10348.0 True False 19611.29365170383 16721.193249731325 16369.592928951019 19369.94240968356 16411.389942461 16542.889146309644 17548.86765966801 17683.142769181883 17572.577605165246 12136.638012156714 1.6158753051759551 1.3777450751173819 1.3487749171190857 1.5959891355646907 1.3522187879396634 1.3630536833791524 1.4459414248072746 1.4570050413853892 1.4478950091090794 1.0 13.567081213422734 -10.728130545720491 5.031913673010729 0.9999559267394433 1.439830094238617 0.6858889375304751 0.09027230230807935 4.3406857348814803e-05 6.855480320529781e-06 0.08500175739704634 0.02061389423904529 1.870119911606558e-11 10.728130545720491 0.43987416749917374 GQFSTDELVAEVEKR ddPTM_PC-9_AZD4547_30min_R2 2 GQFSTDELVAEVEKR 15 1 A0A087WVQ6;Q00610-2;Q00610;A0A087WX41;P53675-2;P53675 A0A087WVQ6 CLTC;CLTCL1 Clathrin heavy chain;Clathrin heavy chain 1;Clathrin heavy chain 2 0 ; 113.52 0.00013023 4420900.0 45563.0 41570.0 49403.0 67359.0 59210.0 52169.0 46596.0 53607.0 44715.0 50772.0 False True 60051.086230725974 55006.68955434365 48747.88394065325 51830.42323617595 50989.71353899555 48906.86418296914 50742.953731587135 45323.269916311794 47078.543612518224 48994.48773379405 1.2256702541111704 1.1227118008298447 0.9949667033058761 1.0578827462752673 1.0407234751803578 0.9982115630782589 1.0356869941633675 0.9250687579911153 0.9608947004061786 1.0 15.580331823339272 -1.5228787452805286 0.5253816769742341 0.9836008940999611 10.173144069450665 0.804826501797239 0.03598548399490217 53.379419021634085 0.5273733214676676 0.019918507881982368 547.9095350540584 0.029999999999986805 1.5228787452805286 9.189543175350703 GQFSTDELVAEVEKR ddPTM_PC-9_Lapatinib_30min_R1 2 GQFSTDELVAEVEKR 15 1 A0A087WVQ6;Q00610-2;Q00610;A0A087WX41;P53675-2;P53675 A0A087WVQ6 CLTC;CLTCL1 Clathrin heavy chain;Clathrin heavy chain 1;Clathrin heavy chain 2 0 ; 157.58 0.00014671 10163700.0 37394.0 30973.0 37315.0 35879.0 39898.0 36093.0 35863.0 32787.0 35435.0 30624.0 False True 36860.754702780265 30901.283921475442 34247.10474006548 38517.66134883533 37551.27808248604 34549.386526892406 37719.8106609933 34310.40371482816 31443.937152907656 35917.31759608497 1.0262669143978094 0.8603449809081433 0.9534983966563932 1.0723980499321533 1.0454922749180795 0.9619144423707836 1.0501845122505697 0.955260749164855 0.875453381750732 1.0 15.132391989224018 -5.537022403133007 24.941343846748854 0.99695610679519 0.934209861738834 0.09817775562812037 0.06523007717666013 420.3920722734297 741328.908375976 0.017975466259539354 0.03115210252554606 2.9038728539708212e-06 5.537022403133007 -0.06274624505635595 GQGESDPLDHEPAVS(ph)PLLPR ddPTM_PC-9_AZD4547_30min_R2 3 GQGESDPLDHEPAVSPLLPR 20 0 P00519-2;P00519 P00519-2 ABL1 Tyrosine-protein kinase ABL1 1 GQGESDPLDHEPAVS(1)PLLPR;GQGESDPLDHEPAVS(1)PLLPR;GQGESDPLDHEPAVS(1)PLLPR 135.43 6.8584e-06 55213000.0 24552.3 26766.2 80109.0 112288.0 95821.0 80673.0 72156.0 107093.0 69202.0 86196.0 True False 32359.42068043482 35417.850708430895 79046.70231770928 86401.7364323062 82517.90814085622 75628.50455697202 78577.74421530613 90544.23760232025 72859.87644131694 83178.30427602059 0.38903679225116994 0.4258063567982773 0.9503283699484794 1.038753280489933 0.9920604760951498 0.909233546118046 0.9446903841000669 1.088555944851393 0.8759480861684464 1.0 16.34391965316665 -5.2616220310613 4.97117737194173 0.9797040125593895 0.3974445519997472 0.9400461676962875 0.05740003378244657 0.034290727580109544 2.676419312790113 0.014709249758732239 0.036332643662634556 5.474922411975479e-06 5.2616220310613 -0.5822594605596423 down GQGESDPLDHEPAVS(ph)PLLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GQGESDPLDHEPAVSPLLPR 20 0 P00519-2;P00519 P00519-2 ABL1 Tyrosine-protein kinase ABL1 1 GQGESDPLDHEPAVS(1)PLLPR;GQGESDPLDHEPAVS(1)PLLPR;GQGESDPLDHEPAVS(1)PLLPR;GQGESDPLDHEPAVS(1)PLLPR;GQGESDPLDHEPAVS(1)PLLPR 112.62 3.7924e-05 58907700.0 25370.2 38704.899999999994 55328.8 63390.7 78438.5 61450.6 50191.7 57370.5 55781.399999999994 45775.4 True False 29664.87377570933 42547.26668022716 56648.04842764251 59839.12459442229 63069.039000483586 58228.02235840129 45437.178819560184 55864.5851640694 56597.09744695912 54074.11766213301 0.5485965385706706 0.7868323796991354 1.0476000511296732 1.1066130559597904 1.1663443016223183 1.0768187235568558 0.840275917278238 1.0331113586193608 1.0466578077258744 1.0 15.72265059919393 -4.987036519049686 2.3500711240768193 1.0428437434142417 0.5245154779151118 0.7923364266232281 0.08064018026174767 0.18145620542908128 1.6538496844156683 0.024079074006321703 0.16232585743872446 1.0302994807501763e-05 4.987036519049686 -0.5183282654991299 GQGESDPLDHEPAVS(ph)PLLPR ddPTM_PC-9_Lapatinib_30min_R1 4 GQGESDPLDHEPAVSPLLPR 20 0 P00519-2;P00519 P00519-2 ABL1 Tyrosine-protein kinase ABL1 1 GQGESDPLDHEPAVS(1)PLLPR;GQGESDPLDHEPAVS(1)PLLPR;GQGESDPLDHEPAVS(1)PLLPR;GQGESDPLDHEPAVS(1)PLLPR 144.48 3.3828e-05 49297700.0 69074.2 52524.4 85081.8 55250.6 68676.7 69068.0 57874.8 56685.3 77056.0 44165.1 True False 68089.18924134315 52402.782978889496 78086.7028292457 59313.91343459857 64637.2715295871 66114.12264537177 60871.273960428756 59319.10597786159 68377.14184434744 51798.97868870339 1.3144890298038332 1.0116566833067269 1.5074950280105672 1.1450788207825047 1.2478483778230083 1.2763595792631004 1.175144288582352 1.145179064906896 1.3200480699682116 1.0 15.660636032378875 -11.678077508486233 2.36910130956183 0.4554587254725909 1.233489960804927 0.2418359316838683 0.12625587917827125 7624787.351742921 693432.3729916792 22589137.486974746 0.02917032142239649 2.0985653194891173e-12 11.678077508486233 0.7780312353323361 GQGSS(ph)PVAMQK ddPTM_PC-9_AZD4547_30min_R2 1 GQGSSPVAMQK 11 0 P18206;P18206-2 P18206 VCL Vinculin 1 GQGS(0.008)S(0.992)PVAMQK 89.189 0.008293799999999999 5024600.0 19543.0 16907.0 26360.0 30921.0 26947.0 23735.0 21208.0 27285.0 25397.0 24033.0 True False 25757.267480347586 22371.857115595074 26010.44917668198 23792.641174687797 23205.87418907809 22250.846697900535 23095.470914660073 23068.730196925182 26739.43357099689 23191.61198507589 1.1106285969652616 0.9646529585779401 1.1215455481671583 1.0259158005057465 1.0006149725172782 0.9594351057709679 0.9958544895250193 0.9947014554990923 1.1529786540152565 1.0 14.501315480777436 -4.732270616879052 24.21268993312164 1.0232863926147802 1.1106293420734117 0.15572776453464376 0.06051659706333278 4527.436668148098 3757873.942948543 0.014953105289715945 1.5347657721206418 1.8523770135375023e-05 4.732270616879052 0.08734294945863152 GQGSS(ph)PVAMQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GQGSSPVAMQK 11 0 P18206;P18206-2 P18206 VCL Vinculin 1 GQGS(0.427)S(0.573)PVAMQK 65.695 0.038793 3251800.0 18209.0 19280.0 19940.0 20643.0 23532.0 19196.0 23274.0 18492.0 18101.0 13225.0 True False 21291.42405585652 21193.99098291895 20415.4452228711 19486.439635508978 18921.073525875447 18189.327967373316 21069.31823083188 18006.60459389357 18365.69288127237 15622.587810957593 1.3628615382736295 1.35662485878643 1.3067902366694861 1.2473246987827011 1.2111356809020024 1.1642967341566437 1.3486445706551882 1.1526006326086284 1.175585831458139 1.0 13.931345828727547 -7.468928402401647 0.034637138102713044 5.3857474881575116e-12 2.4215034612430815 0.7494753034664777 0.05492486659733874 56.22763486274545 1.4407437230131226 48.03664637218539 51.790410153423046 3.396812676798526e-08 7.468928402401647 2.4215034612376956 GQGT(ph)PPSGPGVVR ddPTM_PC-9_AZD4547_30min_R2 1 GQGTPPSGPGVVR 13 0 A0A669KBI7;Q9UMN6 A0A669KBI7 KMT2B Histone-lysine N-methyltransferase 2B 1 GQGT(0.939)PPS(0.061)GPGVVR 109.1 0.0020143 17536000.0 23814.0 22321.0 25442.0 38340.0 33316.0 31072.0 24258.0 35618.0 24743.0 31312.0 True False 31386.356638028843 29535.826739054686 25104.62245649252 29501.305347095175 28690.648476020546 29129.062928045707 26416.91500602714 30114.05652021554 26050.864466164345 30215.776410631046 1.038740696631113 0.977496865798321 0.8308448578425333 0.9763543701864138 0.9495254428056363 0.9640348979348751 0.8742755654206084 0.9966335503336688 0.862161015230397 1.0 14.883014392888569 -5.000199659353251 12.802384153308319 0.9310223232731182 1.0234963632357417 0.26285570168650774 0.05547967898103493 0.0777436783024718 1246.0265751288277 0.012957484288027515 0.04473460917071073 9.99540373010389e-06 5.000199659353251 0.09247403996262349 GQGT(ph)PPSGPGVVR ddPTM_PC-9_Lapatinib_30min_R1 2 GQGTPPSGPGVVR 13 0 A0A669KBI7;Q9UMN6 A0A669KBI7 KMT2B Histone-lysine N-methyltransferase 2B 1 GQGT(0.641)PPS(0.359)GPGVVR;GQGT(0.672)PPS(0.328)GPGVVR 113.65 0.00078469 30900000.0 76228.0 80006.0 82872.0 62708.0 73046.0 75385.0 61475.0 64151.0 74964.0 59795.0 True False 75140.97474149679 79820.75102255384 76058.58405517113 67319.75550775576 68749.57789396157 72160.95928101809 64657.87470051485 67131.68965473946 66520.76491408402 70130.48607817072 1.071445229364889 1.1381747865483478 1.0845295435481892 0.9599214160973876 0.9803094451296127 1.0289527895269983 0.9219653009169814 0.9572397598943109 0.9485285021400944 1.0 16.09775410699196 -5.707984255704911 4.937289886537429 0.9697874615248389 1.1055370596964822 0.7744856499565489 0.03146871497796634 0.0874246766881209 4.439907370226939 0.008790889803719322 0.015243844978779479 1.958915687964821e-06 5.707984255704911 0.13574959817164334 GQGTPPS(ph)GPGVVR ddPTM_PC-9_AZD4547_30min_R2 1 GQGTPPSGPGVVR 13 0 A0A669KBI7;Q9UMN6 A0A669KBI7 KMT2B Histone-lysine N-methyltransferase 2B 1 GQGT(0.361)PPS(0.639)GPGVVR 82.57799999999999 0.010356 17553000.0 12703.0 13619.0 20820.0 25235.0 21493.0 18768.0 15965.0 22963.0 14112.0 19750.0 True False 16742.28976118587 18021.07541593951 20543.913196453675 19417.460626863507 18509.06794618529 17594.433993098686 17385.854071696896 19414.59598724547 14857.931509781009 19058.55851143213 0.8784656904216097 0.9455634016145401 1.0779363604089243 1.0188315456919836 0.9711683039975331 0.9231775835798285 0.912233423176686 1.0186812384367776 0.7795936665865151 1.0 14.218151385100954 -6.674428223092163 4.509772910291718 0.9269813005944164 0.9857078840643115 0.10107129734597586 0.0764549388301328 0.5019941097557206 18.387634554990505 0.02605282516280464 0.02570818034369707 2.116273418006838e-07 6.674428223092163 0.05872658346989512 GQGTPPS(ph)GPGVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GQGTPPSGPGVVR 13 0 A0A669KBI7;Q9UMN6 A0A669KBI7 KMT2B Histone-lysine N-methyltransferase 2B 1 GQGT(0.371)PPS(0.629)GPGVVR;GQGT(0.338)PPS(0.662)GPGVVR 95.195 0.0035769 25640000.0 43645.0 46965.0 56589.0 58193.0 62668.0 58732.0 55670.0 57303.0 50881.0 39803.0 True False 51033.236471956625 51627.374819128 57938.29637497761 54932.63487425155 50388.655266002104 55651.99052822304 50396.53458410287 55798.85696754722 51625.03836760509 47018.96881962536 1.0853754931914996 1.0980116347761997 1.2322323910854167 1.168307945777898 1.0716665322734653 1.1836072105646502 1.0718341097065434 1.1867307677801984 1.0979619430968293 1.0 15.520955278916269 -8.541409792863247 21.19014520294775 0.9999999971395406 1.1376140950459444 0.38644338864881544 0.05234105709645597 463.1044000648553 529558.5149919766 0.049847603636546216 0.01287059591596509 2.874684631226589e-09 8.541409792863247 0.13761409790640378 GQHEMSEMDGR ddPTM_PC-9_Lapatinib_30min_R1 1 GQHEMSEMDGR 11 0 Q14126 Q14126 DSG2 Desmoglein-2 0 85.973 0.0064256 1110500.0 5639.9 6257.2 4109.9 2222.8 2857.9 2713.3 994.25 2770.9 4615.8 731.09 False True 5559.4739917690085 6242.711837841222 3771.9998866727847 2386.2721270434295 2689.803940847582 2597.2584840112268 1045.7274000973869 2899.646129667776 4095.9199974711782 857.457932383809 6.483669672648754 7.280487592535217 4.399049497607762 2.782961165697519 3.13695149261689 3.0290214667332056 1.219567002185369 3.381677421312674 4.776817430662934 1.0 9.74392208294938 -5.462163074255776 2.779180904569413 2.82299729416445 6.909626368597185 0.7135792378210766 1.034232623436508 0.14347134987299737 2.158754798569683 0.28873668902958555 0.6819502131919529 3.45014164830587e-06 5.462163074255776 4.086629074432735 GQIIY(ph)T(ph)WQGANATRDELT(ph)T(ph)SAFLT(ph)VQLDR ddPTM_PC-9_Lapatinib_30min_R1 1 GQIIYTWQGANATRDELTTSAFLTVQLDR 29 1 Q9Y6U3-3;Q9Y6U3-2;Q9Y6U3 Q9Y6U3-3 SCIN Adseverin 5 GQIIY(0.983)T(0.986)WQGANAT(0.033)RDELT(0.721)T(0.721)S(0.721)AFLT(0.837)VQLDR 60.81399999999999 0.026991 0.0 21236.0 20112.0 16858.0 18543.0 19840.0 17984.0 14395.0 15364.0 16360.0 15873.0 True False 20933.17074579456 20065.4318996776 15472.000313761853 19906.714077634668 18673.05020694079 17214.86624275159 15140.302664724057 16077.867529039562 14517.364521562555 18616.62690055699 1.1244341339390684 1.0778231742441626 0.831085050820831 1.0692975791999721 1.0030308018034197 0.9247038324776514 0.813267771095046 0.8636294649359133 0.77980638485741 1.0 14.18430407786649 -6.917569580122588 2.9291324291025016 0.8532911323397193 1.01733156029265 0.4012131281599626 0.09030622580473875 0.26733552896695595 4.636775909237854 0.035119535736113476 0.029888499290706257 1.209011466677431e-07 6.917569580122588 0.16404042795293072 GQKPALDCSQVSPPRPAT(ph)SPENNASLSDTSPMDSSPSGIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GQKPALDCSQVSPPRPATSPENNASLSDTSPMDSSPSGIPK 41 2 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;F5GZ28;M0QY71;M0R1G7 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 GQKPALDCS(0.019)QVS(0.024)PPRPAT(0.242)S(0.242)PENNAS(0.242)LS(0.07)DT(0.07)S(0.07)PMDS(0.01)S(0.011)PS(0.001)GIPK 45.178999999999995 0.0017682000000000002 11974000.0 20668.0 22220.0 17779.0 23127.0 26777.0 20470.0 19245.0 18793.0 17707.0 21859.0 True False 24166.684188392723 24425.854753135824 18202.918787232975 21831.269168745646 21530.239070302858 19396.51716462449 17421.974278265854 18299.703662829415 17965.93137664714 25821.863664251214 0.9359000768736152 0.9459369420709909 0.7049420996066136 0.8454567591482446 0.8337988051617727 0.7511664307746221 0.6746985618387223 0.7086902750619132 0.6957643185731737 1.0 14.656305508860077 -5.249372184133189 24.104583735778615 0.7663343787370578 0.9409185645412229 0.3288096224945337 0.09282293713882606 494.38480064761177 987540.4448280504 0.023205961590247418 0.06026775797164818 5.631548333659854e-06 5.249372184133189 0.17458418580416513 GQKS(ph)PGALETPSAAGSQGNTASQGK ddPTM_PC-9_AZD4547_30min_R2 2 GQKSPGALETPSAAGSQGNTASQGK 25 1 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 GQKS(0.454)PGALET(0.374)PS(0.132)AAGS(0.039)QGNT(0.001)ASQGK;GQKS(0.879)PGALET(0.12)PSAAGSQGNTASQGK 112.88 3.5257e-08 64116600.0 88194.0 53558.0 108188.0 194052.0 154483.0 108447.0 91245.0 97744.0 80243.0 120135.0 True False 116237.85745084037 70869.57611622642 106753.35643121664 149316.3094735137 133035.70202068303 101665.79194637525 99365.62823501315 82639.91073367235 84484.48116066867 115929.11021624801 1.0026632416484216 0.6113182097579295 0.9208503043979601 1.2879966834472119 1.1475607961841965 0.876965170842192 0.8571240480467915 0.7128486588012299 0.7287598516289464 1.0 16.822883352182053 -7.100482564081445 3.312767484865612 0.8004185595009148 0.9861305233169447 0.1578928358103434 0.179055747727987 0.5021106349333795 10.385460366810076 0.08081789227058249 0.06184129617477381 7.934461111631265e-08 7.100482564081445 0.18571196381602995 GQKS(ph)PGALETPSAAGSQGNTASQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GQKSPGALETPSAAGSQGNTASQGK 25 1 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 GQKS(0.989)PGALET(0.011)PSAAGSQGNTASQGK;GQKS(0.992)PGALET(0.008)PSAAGSQGNTASQGK;GQKS(0.999)PGALET(0.001)PSAAGSQGNTASQGK;GQKS(0.995)PGALET(0.005)PSAAGSQGNTASQGK 133.47 2.6224000000000004e-09 105286000.0 173563.0 80205.0 130256.0 223603.0 238882.0 261721.0 228958.0 348363.0 249358.0 174511.0 True False 202943.787874492 88167.22234362118 133361.79703863064 211075.24884070668 192074.7869287855 247995.89002651162 207269.44072762722 339218.8403711083 253004.38901101094 206148.46287168458 0.9844545287772177 0.4276879929902759 0.6469211323765272 1.0238992127343134 0.9317303862136527 1.2029965519601018 1.0054377211468242 1.645507493219837 1.2272921441499733 1.0 17.65332417837118 -6.3814639363310945 0.9915747153413186 1.2782823401792172 0.6619661797851278 0.4877177756160147 0.22249443381991152 0.4169074141100979 0.8763469343986046 0.10670860872835009 0.14579103909031463 4.1546655001318e-07 6.3814639363310945 -0.6163161603940893 GQKS(ph)PGALETPSAAGSQGNTASQGK ddPTM_PC-9_Lapatinib_30min_R1 4 GQKSPGALETPSAAGSQGNTASQGK 25 1 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 GQKS(0.992)PGALET(0.007)PS(0.001)AAGSQGNTASQGK;GQKS(0.994)PGALET(0.006)PSAAGSQGNTASQGK;GQKS(1)PGALETPSAAGSQGNTASQGK;GQKS(0.891)PGALET(0.108)PS(0.001)AAGSQGNTASQGK 157.01 2.885e-09 113850900.0 294159.0 135458.0 210155.0 185236.0 176038.0 163146.0 120228.0 115338.0 200394.0 119026.0 True False 289964.23871784576 135144.35532351464 192876.86712175998 198858.87336918156 165683.79094402413 156168.62589190117 126452.81755987793 120697.02454207023 177823.5174776288 139599.48550782402 2.0771153823600184 0.9680863423808271 1.3816445413113643 1.424495746856003 1.1868510141087747 1.118690554795408 0.9058258137548131 0.8645950527898301 1.2738121263896955 1.0 17.09093409895946 -4.755310180878389 24.99990677245843 1.1329408039711293 2.077116930640126 0.7068180376154637 0.18391658245356887 123.51934655763712 503764.75721174193 0.04991456812745893 0.44817043763539427 1.7566685217632778e-05 4.755310180878389 0.9441761266689968 GQKSPGALET(ph)PSAAGSQGNTASQGK ddPTM_PC-9_AZD4547_30min_R2 1 GQKSPGALETPSAAGSQGNTASQGK 25 1 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 GQKS(0.004)PGALET(0.987)PS(0.009)AAGSQGNTASQGK 131.26 1.8029e-07 48022000.0 21081.0 14173.0 25812.0 42220.0 36912.0 21560.0 17681.0 23402.0 16758.0 26594.0 True False 27784.319487960256 18754.14508187905 25469.71601473882 32486.831292497598 31787.405947498803 20211.849791730998 19254.574747364415 19785.7586244619 17643.793667864946 25662.95215458363 1.082662638366714 0.7307867375862054 0.9924702295090281 1.265903902902892 1.2386496205122408 0.7875886480239174 0.7502868193566491 0.7709852905963507 0.6875200312725366 1.0 14.647399520896629 -6.817853838755494 13.961091466444008 0.7818005030245679 1.0511225367606483 0.4094522258489689 0.1568407250920189 1.6325392727871155 402.3950597202118 0.05999119996065116 0.052914862202141096 1.5210593541532236e-07 6.817853838755494 0.2693220337360803 GQLCELSCSTDYR ddPTM_PC-9_Lapatinib_30min_R1 1 GQLCELSCSTDYR 13 0 E9PKG1;Q99873-2;Q99873-3;Q99873;Q99873-5 E9PKG1 PRMT1 Protein arginine N-methyltransferase 1 0 204.32 4.4913e-09 5946900.0 19885.0 27094.0 24718.0 26423.0 28950.0 30147.0 31536.0 26222.0 25261.0 25464.0 False True 19601.436253537617 27031.26550765041 22685.781454239255 28366.235564544066 27247.21791788989 28857.683086089397 33168.77977316692 27440.369848117374 22415.840169877247 29865.418471352805 0.6563255181687644 0.905102519610735 0.7596003208861671 0.9498020458596028 0.9123333712543048 0.9662574496911859 1.1106082375836364 0.9188007820629883 0.7505617304970541 1.0 14.866188316373915 -3.852858820795617 0.650735484979723 0.949425398459969 6.344362801718415e-18 0.3998635212844728 0.09880809105953078 10.601219706891476 1.380189161960326 0.043959768455591554 9.854936365000961 0.00014032698013463003 3.852858820795617 -0.949425398459969 GQLTNIVS(ph)PTAATTPR ddPTM_PC-9_AZD4547_30min_R2 1 GQLTNIVSPTAATTPR 16 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 GQLT(0.001)NIVS(0.497)PT(0.497)AAT(0.005)TPR 162.82 6.374399999999999e-05 15216000.0 17835.0 21475.0 23511.0 31776.0 26569.0 29008.0 19692.0 28720.0 23257.0 23439.0 True False 23506.159008954575 28416.373783486386 23199.228778185505 24450.5341343061 22880.352964323123 27194.125174328998 21444.54985154122 24281.983919944687 24486.317539893484 22618.40774427634 1.0392490609734844 1.256338381762405 1.0256791300464614 1.0810015634497254 1.0115810636632045 1.2023005987771422 0.9481016565795984 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394212.94272082625 377381.9364404891 440919.0144175611 368809.64442958205 0.7110719227131318 0.8656240993371793 0.8791944077535944 0.8090504818525651 1.2688435389469872 0.9721572395829082 1.068879159411718 1.0232431340676174 1.195519209101776 1.0 18.492516857397128 -6.233542221470156 24.829892917912474 1.0825103239590497 0.8242600372612794 0.6679941299963781 0.09378001369690243 413.56879292656544 368097.2506093111 0.02663298389375358 0.03437594708626945 5.840604228381883e-07 6.233542221470156 -0.2582502866977703 GQS(ph)LDNLIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GQSLDNLIK 9 0 O95171-2;O95171 O95171-2 SCEL Sciellin 1 GQS(1)LDNLIK;GQS(1)LDNLIK;GQS(1)LDNLIK;GQS(1)LDNLIK;GQS(1)LDNLIK 124.12 0.001469 71047300.0 309644.0 289760.0 349959.0 486162.0 561703.0 503091.0 432989.0 447055.0 345040.0 376303.0 True False 362060.6134522291 318525.45784287294 358303.34978689876 458923.91929847066 451641.3293687235 476708.02231891034 391973.14735110657 435320.2799439269 350085.55724845146 444523.7550870899 0.8144910352007964 0.7165544117669669 0.8060387002640633 1.0323945886953994 1.0160116848653884 1.0724016812678885 0.8817822284307668 0.979295875557067 0.7875519659908021 1.0 18.761900992323362 -5.648011091449512 5.520144434415098 0.9685916488596543 0.7651280354508131 0.5408727286109807 0.07978071203936993 0.1541469510186274 6.818719254141513 0.022244324454410838 0.03904081733108313 2.2489971679494748e-06 5.648011091449512 -0.20346361340884123 GQS(ph)LDNLIK ddPTM_PC-9_Lapatinib_30min_R1 4 GQSLDNLIK 9 0 O95171-2;O95171 O95171-2 SCEL Sciellin 1 GQS(1)LDNLIK;GQS(1)LDNLIK;GQS(1)LDNLIK;GQS(1)LDNLIK 124.12 0.001469 77970000.0 263669.0 215576.0 234813.0 251028.0 215230.0 202322.0 187092.0 224207.0 245825.0 277049.0 True False 259909.0317090274 215076.84701695034 215507.58154439187 269489.43652485934 202570.59455846073 193669.1596956177 196778.70831181336 234624.47572789498 218137.59984799015 324936.5505054116 0.7998762567792409 0.6619041369227818 0.6632297327253209 0.8293601815668047 0.6234158460886569 0.5960214675584559 0.6055911777414408 0.7220624314591765 0.671323676910755 1.0 18.30979850886152 -10.691742819611608 4.8476115986078385 1.0000281266682576 0.6829394028941069 0.6186863082568244 0.07395288461254046 2.4386635805702083e-05 4.180995784129809e-06 0.07367015589476611 0.017865968122022055 2.033560887979825e-11 10.691742819611608 -0.31708872377415065 GQS(ph)PAGDGSPEPPTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GQSPAGDGSPEPPTPR 16 0 A0A0A0MRW6;Q9H6R4-3;Q9H6R4-2;Q9H6R4-4;Q9H6R4 A0A0A0MRW6 NOL6 Nucleolar protein 6 1 GQS(1)PAGDGSPEPPTPR 137.91 9.3346e-07 0.0 8626.4 6152.4 7866.0 10695.0 10548.0 10756.0 11488.0 11271.0 7864.8 7355.7 True False 10086.679140833701 6763.169612204899 8053.555271971125 10095.79382365783 8481.195119451562 10191.936425144166 10399.77347408252 10975.148192611634 7979.807821260202 8689.230182310841 1.1608254044607687 0.7783393315984501 0.9268433570060332 1.1618743676753334 0.9760582861203531 1.172938938352959 1.1968578638017817 1.2630748596065928 0.9183561321122727 1.0 13.085012652569642 -5.753380621781747 24.96124268501134 1.1115171389575418 0.9376363056264511 0.18509939952691667 0.1341502977823972 242.25600137968465 750356.2723061721 0.035702223013493725 0.06048521147504437 1.764490718393787e-06 5.753380621781747 -0.17388083333109072 GQS(ph)PAGDGSPEPPTPR ddPTM_PC-9_Lapatinib_30min_R1 1 GQSPAGDGSPEPPTPR 16 0 A0A0A0MRW6;Q9H6R4-3;Q9H6R4-2;Q9H6R4-4;Q9H6R4 A0A0A0MRW6 NOL6 Nucleolar protein 6 1 GQS(1)PAGDGSPEPPTPR 123.92 3.7205e-05 3454100.0 14943.0 14049.0 22746.0 18304.0 16139.0 14394.0 12116.0 10867.0 13669.0 12292.0 True False 14729.910079789415 14016.470403667981 20875.911682099122 19650.137220354023 15189.735750494829 13778.40217405284 12743.307195956697 11371.92049193392 12129.453279048812 14416.65582193954 1.0217286353866588 0.9722414529961555 1.4480412059452628 1.3630163238308064 1.053624081625005 0.9557280373638807 0.8839294877639855 0.7888043269110938 0.8413499932897046 1.0 13.815448926330955 -6.699987461287252 2.4979365184814535 0.869612987394784 1.2017469209853504 0.5056145518759796 0.14255545627167393 0.25011964777561246 3.1906113106660055 0.058290683556279664 0.05600274732772435 1.9953199219227403e-07 6.699987461287252 0.3321339335905664 GQS(ph)PPSKDGSGDYQSR ddPTM_PC-9_AZD4547_30min_R2 1 GQSPPSKDGSGDYQSR 16 1 Q8N4C8;Q8N4C8-4;Q8N4C8-3;Q8N4C8-2;Q8N4C8-5 Q8N4C8;Q8N4C8-3 MINK1 Misshapen-like kinase 1 1 GQS(0.488)PPS(0.488)KDGS(0.014)GDY(0.007)QS(0.002)R 95.87299999999999 0.011597 3693700.0 4845.9 4241.6 4480.7 6731.9 8049.3 5901.7 6062.9 7960.0 6486.9 4809.5 True False 6386.795399018385 5612.614250991197 4421.282990362631 5179.964461818202 6931.793636031699 5532.665766041689 6602.486354606399 6729.964902603058 6829.784290731174 4641.120868897866 1.3761320981358254 1.209323008285288 0.9526325892504841 1.1161020383096154 1.4935602480178032 1.192096892610241 1.4226059913355158 1.4500731811798802 1.47158078482732 1.0 12.18025755482455 -6.242636134106746 24.543333812120487 1.357726373385485 1.1517517518447187 0.1933283558954184 0.17150294615742226 948.4605673504561 1237997.801109999 0.05020978652463328 0.06469892572033165 5.719576404991897e-07 6.242636134106746 -0.2059746215407663 GQS(ph)SPPPAPPICLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GQSSPPPAPPICLR 14 0 O43379;O43379-4;H7C3R4;O43379-3;O43379-2 O43379 WDR62 WD repeat-containing protein 62 1 GQS(0.683)S(0.317)PPPAPPICLR 105.66 0.0009501 30517000.0 23361.0 30686.0 31736.0 34925.0 28410.0 27791.0 34653.0 26390.0 20878.0 22004.0 True False 27315.555899218223 33732.303283290996 32492.706599450237 32968.2654783777 22843.26444289142 26333.59103674058 31370.416974006057 25697.29046251629 21183.301252704525 25993.151016431853 1.0508751279115947 1.297738133478575 1.250048775498962 1.2683443210689023 0.8788185945001744 1.0130972970569638 1.2068724162828472 0.9886177495860916 0.814957033847619 1.0 14.665843914484126 -6.2497803439312385 24.784839814630512 0.9957838353590489 1.2249147253426758 0.4995451971126168 0.11376175805689712 609.8467444447556 1296414.961626875 0.035008802544409724 0.044809915843697236 5.626258163188562e-07 6.2497803439312385 0.22913088998362685 GQS(ph)SPPPAPPICLR ddPTM_PC-9_Lapatinib_30min_R1 3 GQSSPPPAPPICLR 14 0 O43379;O43379-4;H7C3R4;O43379-3;O43379-2 O43379 WDR62 WD repeat-containing protein 62 1 GQS(0.858)S(0.142)PPPAPPICLR;GQS(0.5)S(0.5)PPPAPPICLR;GQS(0.5)S(0.5)PPPAPPICLR 149.82 0.00011671 64596000.0 216236.0 204013.0 214125.0 185677.0 204761.0 210128.0 197432.0 185523.0 203579.0 155358.0 True False 213152.43498717397 203540.62043302145 196520.4690464028 199332.30598031418 192717.36055561475 201141.31527229206 207654.06291780467 194143.07586500936 180649.78923809194 182211.42329847754 1.1698082981219704 1.1170574091812284 1.0785299049252575 1.09396163188842 1.0576579506759443 1.103889710266989 1.1396325167695438 1.0654824618047507 0.9914295490803147 1.0 17.47525388264075 -1.5230080552068628 0.044832804491034765 0.7746959116043859 1.6209567689863253 0.5634719507483937 0.03538729307475308 526.0602614753881 1.7955291045588435 8.642636223198053 32.1969046221972 0.02999106891639235 1.5230080552068628 0.8462608573819395 GQS(ph)SPPPAPPICLRR ddPTM_PC-9_Lapatinib_30min_R1 2 GQSSPPPAPPICLRR 15 1 O43379;O43379-4;H7C3R4;O43379-3;O43379-2 O43379 WDR62 WD repeat-containing protein 62 1 GQS(0.5)S(0.5)PPPAPPICLRR;GQS(0.5)S(0.5)PPPAPPICLRR 64.22399999999999 0.016678 7724600.0 71920.0 50418.0 56820.0 47174.0 49080.0 44835.0 41802.0 43924.0 51719.0 31196.0 True False 70894.40761148746 50301.260218672716 52148.47893154277 50643.33332785079 46193.2108949926 42917.511565489745 43966.303021243126 45964.86939244556 45893.86159478571 36588.18703394287 1.9376310596017972 1.3747950990850741 1.425281850755945 1.3841443764586903 1.2625170755834156 1.1729881976845467 1.2016529537376524 1.2562762224267614 1.2543354922781487 1.0 15.159090310614806 -1.5228787452803398 0.6040159217517546 1.2032932064556405 44.66936003423214 0.8250919174941314 0.09798140025081303 69.83820294929706 0.5335362941907388 0.04288695475044322 4011.0432162572647 0.029999999999999843 1.5228787452803398 43.4660668277765 GQS(ph)TDSLPQTICR ddPTM_PC-9_AZD4547_30min_R2 1 GQSTDSLPQTICR 13 0 Q96NE9-3;Q96NE9-2;Q96NE9 Q96NE9-3 FRMD6 FERM domain-containing protein 6 1 GQS(0.978)T(0.019)DS(0.002)LPQTICR 121.99 0.0010754000000000002 0.0 16998.0 20961.0 32862.0 38382.0 38534.0 31710.0 31022.0 33886.0 43024.0 29534.0 True False 22403.010419636088 27736.233335304223 32426.22840835065 29533.62289598871 33184.219245256776 29727.16868718879 33782.897902422876 28649.69732281498 45298.16080476316 28500.02364944996 0.786069888754933 0.9732003620930162 1.1377614561725624 1.0362666101352058 1.1643576038189436 1.0430576848929216 1.1853638550603405 1.005251703479478 1.5894078321453393 1.0 14.798675495982268 -3.9632512884358926 0.6356554929472858 1.1677572338549695 4.9961209031835876e-14 0.3413738943095217 0.16081514516248516 10.016898235512864 1.420633732737608 0.06818648414749637 10.777037114208758 0.00010883002064661715 3.9632512884358926 -1.1677572338549196 GQS(ph)TDSLPQTICR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GQSTDSLPQTICR 13 0 Q96NE9-3;Q96NE9-2;Q96NE9 Q96NE9-3 FRMD6 FERM domain-containing protein 6 1 GQS(0.614)T(0.114)DS(0.251)LPQT(0.021)ICR 125.84 0.0010977 0.0 5793.3 8374.3 11343.0 9880.6 9511.9 9079.2 9529.2 8345.8 7106.9 5874.8 True False 6773.991267109322 9205.645160179365 11613.460138567056 9327.022015337401 7648.111476745473 8603.070768981863 8626.525190566426 8126.731593106043 7210.82496756614 6939.8547351087855 0.9760998645749227 1.3264896041134588 1.6734442696349912 1.343979430599882 1.1020564217365545 1.2396615055152167 1.2430411759088789 1.1710232999536485 1.039045519366063 1.0 12.760689749319868 -7.870083712580965 0.6718162267822562 0.9934237165734914 1.320718677487421 0.26130675981482143 0.16961385480082994 1.0042479198769851 0.924523870456262 0.1730694057057821 0.0848144908202972 1.3487028878496806e-08 7.870083712580965 0.3272949609139295 GQSEDPGSLLSLFR ddPTM_PC-9_Lapatinib_30min_R1 1 GQSEDPGSLLSLFR 14 0 F5GZS6;J3KPF3;P08195-2;P08195-3;P08195;P08195-4;F5GZI0 F5GZS6 SLC3A2 4F2 cell-surface antigen heavy chain 0 208.82 2.4303999999999997e-10 7811300.0 53947.0 36919.0 34899.0 34583.0 34297.0 38840.0 51493.0 31632.0 40297.0 43030.0 False True 53177.70588733184 36833.51632379658 32029.738934035766 37126.349185506086 32279.71789049638 37178.90374046217 54159.05558281595 33101.738198293344 35758.327513777906 50467.67816612906 1.0536982841231952 0.729843687330896 0.6346584605814548 0.7356460715964364 0.6396117091861901 0.736687422355294 1.0731433969388418 0.6558997639901193 0.7085391841500803 1.0 15.623072094573665 GQSPAGDGS(ph)PEPPTPR ddPTM_PC-9_AZD4547_30min_R2 1 GQSPAGDGSPEPPTPR 16 0 A0A0A0MRW6;Q9H6R4-3;Q9H6R4-2;Q9H6R4-4;Q9H6R4 A0A0A0MRW6 NOL6 Nucleolar protein 6 1 GQS(0.002)PAGDGS(0.602)PEPPT(0.397)PR 109.54 0.00067115 2378300.0 21488.0 17304.0 26758.0 33796.0 33095.0 26182.0 28118.0 30614.0 23394.0 28184.0 True False 28320.73702183438 22897.179601836946 26403.17143663339 26004.854342995008 28500.33051128287 24544.83540107148 30620.44752821633 25883.309739734916 24630.559080202424 27197.28673854194 1.041307439749141 0.8418920542316006 0.970801671889454 0.9561562001750303 1.0479108002672324 0.9024736782396897 1.125864054844241 0.9516872027919993 0.9056255985012599 1.0 14.731175111756729 -6.019896944865124 22.91790848271218 0.9902170913112152 0.944237737551536 0.049095479077600035 0.07665921742420677 739.9682553392573 852320.4272848069 0.021871819380048483 0.028700287583678825 9.552192261737134e-07 6.019896944865124 -0.04597935375967921 GQSPAGDGS(ph)PEPPTPR ddPTM_PC-9_Lapatinib_30min_R1 1 GQSPAGDGSPEPPTPR 16 0 A0A0A0MRW6;Q9H6R4-3;Q9H6R4-2;Q9H6R4-4;Q9H6R4 A0A0A0MRW6 NOL6 Nucleolar protein 6 1 GQS(0.095)PAGDGS(0.587)PEPPT(0.318)PR 94.454 0.016038999999999998 0.0 16434.0 19125.0 22923.0 20780.0 24339.0 19116.0 22862.0 21268.0 22133.0 21066.0 True False 16199.648146373496 19080.71723753649 21038.35942533888 22308.230520047888 22907.427872315093 18298.45324157248 24045.682495374876 22256.188922651225 19640.14846917752 24707.23003131943 0.655664278263426 0.7722726187172481 0.8515061946916022 0.9029029353662666 0.9271548386151395 0.7406112793047605 0.9732245364977798 0.9007966046553495 0.7949150286892231 1.0 14.592645656339904 -4.893113696384944 1.5217929942139996 0.8860625783223467 0.5969373144764318 0.5124079801746875 0.07249668968989605 0.7222801628798983 1.8621037110632888 0.0201633537697477 0.29711345640244874 1.2790464115985796e-05 4.893113696384944 -0.28912526384591486 GQSPPS(ph)KDGSGDYQSR ddPTM_PC-9_AZD4547_30min_R2 1 GQSPPSKDGSGDYQSR 16 1 Q8N4C8;Q8N4C8-4;Q8N4C8-3;Q8N4C8-2;Q8N4C8-5 Q8N4C8;Q8N4C8-3 MINK1 Misshapen-like kinase 1 1 GQS(0.095)PPS(0.656)KDGS(0.217)GDY(0.014)QS(0.017)R 53.946000000000005 0.034008 14836000.0 7136.7 4579.4 9752.1 11556.0 9848.7 8136.6 6746.8 8345.0 7952.9 7589.9 True False 9406.022147418334 6059.601494952159 9622.780782091055 8891.94273842023 8481.378005936593 7627.817115742049 7347.252129716543 7055.471999022926 8373.274057832858 7324.179911185766 1.2842423672653234 0.8273419780005273 1.313837303121784 1.2140530197572177 1.1579969510284025 1.0414568194990073 1.0031501436079608 0.9633122185116645 1.1432370803787704 1.0 12.838451514599576 -6.799350208485613 5.239401114927715 1.0246897492296003 1.1529346704023946 0.19476624993786285 0.13111176920556816 0.34343997147705496 22.65543766916057 0.045952630431132055 0.04147676016531898 1.58726628492723e-07 6.799350208485613 0.1282449211727943 GQSPPS(ph)KDGSGDYQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GQSPPSKDGSGDYQSR 16 1 Q8N4C8;Q8N4C8-4;Q8N4C8-3;Q8N4C8-2;Q8N4C8-5 Q8N4C8;Q8N4C8-3 MINK1 Misshapen-like kinase 1 1 GQS(0.019)PPS(0.98)KDGS(0.001)GDYQSR 57.413999999999994 0.027197000000000002 6374500.0 20003.0 22594.0 24516.0 28311.0 31277.0 20770.0 27845.0 27666.0 26731.0 22282.0 True False 23389.11282274141 24836.983001455956 25100.55441744776 26724.826455500403 25148.49637382315 19680.784636504686 25207.32001965769 26939.79681455004 27121.890304916393 26321.550215785064 0.8885917672400211 0.9435987925422868 0.9536123143079518 1.0153211431853089 0.9554337099317792 0.7477061371826837 0.9576685192554059 1.0234882289871443 1.0304062672057728 1.0 14.68395683909239 -7.63222442716137 4.965161294822255 1.0190273482761882 0.9210351668801208 0.3142022837044818 0.06596172557815602 0.2849995936153698 11.22456592418041 0.03484996978931505 0.01949824159951754 2.3322525298550818e-08 7.63222442716137 -0.09799218139606747 GQSPPS(ph)KDGSGDYQSR ddPTM_PC-9_Lapatinib_30min_R1 1 GQSPPSKDGSGDYQSR 16 1 Q8N4C8;Q8N4C8-4;Q8N4C8-3;Q8N4C8-2;Q8N4C8-5 Q8N4C8;Q8N4C8-3 MINK1 Misshapen-like kinase 1 1 GQS(0.012)PPS(0.97)KDGS(0.007)GDY(0.003)QS(0.007)R 64.407 0.014275 9518500.0 11014.0 9862.5 11853.0 10210.0 10728.0 8125.2 10094.0 7347.7 11095.0 8718.3 True False 10856.938340279774 9839.663987200194 10878.492093903144 10960.877459561549 10097.000132059511 7777.704136766302 10616.617929678676 7689.100966097627 9845.364264470445 10225.246538595467 1.0617776597659498 0.9622911242345227 1.063885555506362 1.0719426097150246 0.9874578665607829 0.7606373213016575 1.0382750078060188 0.7519721834652014 0.9628485951227536 1.0 13.31984800762808 -6.534629819212635 24.99699912634174 0.8933078502171794 1.0353292634985862 0.3350493493443374 0.09110539672952299 234.78361166243002 499430.5465473783 0.02783560834326511 0.027855192203658542 2.919914809438975e-07 6.534629819212635 0.14202141328140683 GQSQLS(ph)NPTDDSWK ddPTM_PC-9_AZD4547_30min_R2 1 GQSQLSNPTDDSWK 14 0 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 1 GQSQLS(0.998)NPT(0.002)DDSWK 123.76 4.0227e-05 21748000.0 75142.0 74626.0 91774.0 113960.0 98102.0 84194.0 93701.0 111880.0 86418.0 82030.0 True False 99035.59294930543 98747.3951090317 90557.01679593365 87688.28266444872 84482.23066378223 78929.33587036189 102040.20747711066 94591.51674663703 90985.87905415645 79158.1546679889 1.251110430311166 1.2474696450821203 1.144001109876231 1.107760571633302 1.06725871791888 0.9971093464901154 1.289067537073033 1.1949686945505475 1.1494188998692085 1.0 16.27245036027277 -5.2991070800783655 3.713856996004299 1.1237076633642142 1.2524017006682948 0.28796178096766856 0.08240104261856777 0.31262945492748606 9.170623506795458 0.02323525883281319 0.05817628760314793 5.022187467031212e-06 5.2991070800783655 0.12869403730408058 GQSQLS(ph)NPTDDSWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GQSQLSNPTDDSWK 14 0 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 1 GQS(0.007)QLS(0.991)NPT(0.002)DDSWK 90.853 0.0047686000000000004 5507600.0 20768.0 17180.0 17875.0 20365.0 25656.0 25378.0 18947.0 30713.0 21076.0 21857.0 True False 24283.612213302687 18885.516861335454 18301.207791314995 19224.015074220813 20628.890973137026 24047.133004584295 17152.202995599007 29906.816293113396 21384.196628125337 25819.501080083213 0.9405143863153387 0.7314439114357429 0.7088133784828352 0.7445540878034215 0.79896551483134 0.9313554483488413 0.6643119455483967 1.1583034157148404 0.8282188165371172 1.0 14.656173502725766 -7.7546258056917745 24.99998605690695 0.9949458439715048 0.7875003305650293 0.41819879131812265 0.11184902212092995 144.05476876331494 528563.1220719189 0.05157093919880375 0.028918601387466925 1.7594389186806016e-08 7.7546258056917745 -0.20744551340647543 GQSQLSNPT(ph)DDSWK ddPTM_PC-9_AZD4547_30min_R2 1 GQSQLSNPTDDSWK 14 0 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 1 GQSQLS(0.219)NPT(0.774)DDS(0.007)WK 104.55 0.0025816999999999997 24645000.0 110210.0 95376.0 129030.0 151220.0 137340.0 138800.0 119570.0 156470.0 135240.0 136870.0 True False 145254.48748959284 126204.42682066576 127318.97789329563 116358.56532571037 118272.71166096331 130120.8140580829 130211.4983622174 132291.15682290206 142388.51030206788 132078.22295998555 1.0997610676030913 0.9555278984855867 0.9639664665375474 0.880982214312214 0.8954747346714018 0.98517992703085 0.9858665224596965 1.001612179950218 1.0780619780537624 1.0 17.011033089261076 -7.697322582906978 1.7828690715686708 1.0369294233746906 0.9567036077259483 0.1933884487674261 0.058533848114654945 0.5832071065896735 3.601966830004004 0.04383328182521591 0.018567621249299004 2.0076010635980392e-08 7.697322582906978 -0.08022581564874232 GQSQLSNPT(ph)DDSWK ddPTM_PC-9_Lapatinib_30min_R1 2 GQSQLSNPTDDSWK 14 0 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 1 GQSQLS(0.13)NPT(0.869)DDS(0.001)WK;GQSQLS(0.409)NPT(0.556)DDS(0.035)WK 110.55 0.0011842 49475000.0 249820.0 261600.0 224050.0 242990.0 243080.0 263500.0 215550.0 251070.0 264900.0 183940.0 True False 246257.5209886227 260994.28127265626 205629.47385801084 260860.29519087722 228782.5123136674 252230.71924850089 226710.12430574963 262735.6287760971 235064.17247933504 215733.78391535624 1.141487978930748 1.2097979117404165 0.9531630610933434 1.20917684034702 1.0604853266905607 1.1691757993150684 1.0508790982626068 1.2178696540138663 1.08960297368892 1.0 17.71889259470251 -12.19666461138641 1.3516034013958862 0.00017474815546898785 1.122809068336609 0.17070854366129706 0.08093324387691002 334484.19236769225 15966.263525217948 1016058.9495051015 0.021228259767332718 6.358217625396867e-13 12.19666461138641 1.12263432018114 GQSQTS(ph)PDHR ddPTM_PC-9_AZD4547_30min_R2 2 GQSQTSPDHR 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 GQS(0.372)QT(0.15)S(0.478)PDHR;GQS(0.05)QT(0.374)S(0.576)PDHR 108.98 0.0019491 3586900.0 14344.2 11563.599999999999 10775.8 3013.51 9907.2 11303.6 5980.299999999999 8361.4 9781.1 14604.7 True False 18905.35722210521 15301.307561477219 10632.90585121736 2318.7918277653825 8531.756290720095 10596.784105093255 6512.5351146238045 7069.337755857441 10298.10897748859 14093.393898324704 1.3414339625001546 1.0857077913146316 0.754460276064611 0.1645304065503356 0.605372726560511 0.7518972492745629 0.4620984243829271 0.5016064836375417 0.7307046870174214 1.0 13.782731455404019 -5.212081494335822 2.6327118197630064 0.5770402895278355 1.2939173291693027 0.5729514588054906 0.20999535067728725 0.19309197989250734 2.545999857224085 0.055541259051029426 0.195218386263616 6.136468449763756e-06 5.212081494335822 0.7168770396414672 GQSQTS(ph)PDHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GQSQTSPDHR 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 GQS(0.02)QT(0.226)S(0.754)PDHR 98.182 0.004857899999999999 1875900.0 2448.6 4350.6 2660.2 3024.1 9951.1 16375.0 4339.4 5459.5 9285.5 18279.0 True False 2863.0996179455396 4782.498815886262 2723.6292568646786 2854.6694812644846 8001.253389569063 15516.266173459995 3928.3406174646293 5316.193909818405 9421.282871059864 21592.838003515608 0.13259487323895952 0.22148542100429808 0.12613577040781923 0.13220445968240513 0.37055126279678247 0.718583919859619 0.1819279437388009 0.24620172248561564 0.43631517401862374 1.0 14.398265252577263 -14.522878745274987 0.15799906260850305 3.629247713623945 0.08867714169902319 0.6697084097559163 0.1590757988092595 88.04895982181922 0.8019505549069437 72.5508588493549 0.7611937742652252 3.0000000000369603e-15 14.522878745274987 -3.540570571924922 GQSQTS(ph)PDHR ddPTM_PC-9_Lapatinib_30min_R1 2 GQSQTSPDHR 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 GQS(0.049)QT(0.429)S(0.522)PDHR;GQS(0.114)QT(0.19)S(0.697)PDHR 101.72 0.0034935 6347900.0 10537.0 15612.8 8897.0 14200.7 16566.8 8622.4 48422.0 47193.0 14346.6 15814.7 True False 10386.740447750863 15576.649520847574 8165.523003413166 15245.0668501465 15592.37339558197 8253.640051796114 50929.05422933436 49385.75906651675 12730.734831604486 18548.24982323685 0.5599849337126448 0.8397907980155347 0.4402314547857542 0.8219140347704293 0.8406385262316329 0.44498214820549437 2.745760635891993 2.662556280897583 0.6863577401063304 1.0 14.178995442920659 -7.24275372455729 24.85883735794361 1.9122150719252233 0.6720545075919206 0.43433632624605534 0.6155932669715208 644.4006498224358 857292.4751586015 0.23182060875996316 0.17924071506530384 5.718027970577585e-08 7.24275372455729 -1.2401605643333027 GQSS(ph)PPPAPPICLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GQSSPPPAPPICLR 14 0 O43379;O43379-4;H7C3R4;O43379-3;O43379-2 O43379 WDR62 WD repeat-containing protein 62 1 GQS(0.088)S(0.912)PPPAPPICLR;GQS(0.111)S(0.889)PPPAPPICLR;GQS(0.084)S(0.916)PPPAPPICLR 122.1 6.2698e-05 55486000.0 89916.0 101458.0 115012.0 108747.0 114894.0 94214.0 116923.0 90286.0 95791.0 80265.0 True False 105137.00287804902 111530.07972743745 117754.32226543876 102654.25815253079 92381.34547347992 89273.25198573197 105847.20699078616 87916.08816592439 97191.76215623229 94816.40912260982 1.1088481819860245 1.1762740306186317 1.2419192348148016 1.0826634240048643 0.9743181199154984 0.941537997608517 1.1163384900382811 0.927224401129108 1.0250521302757925 1.0 16.532849136048682 -6.003318485528869 4.526281843672873 0.9983787262167966 1.175514034421437 0.6623520970738794 0.05708450127013982 0.1151037000460567 6.084387115920557 0.01658956194485031 0.023625945892791926 9.923880236445742e-07 6.003318485528869 0.1771353082046404 GQSTDS(ph)LPQTICR ddPTM_PC-9_AZD4547_30min_R2 2 GQSTDSLPQTICR 13 0 Q96NE9-3;Q96NE9-2;Q96NE9 Q96NE9-3 FRMD6 FERM domain-containing protein 6 1 GQS(0.161)T(0.023)DS(0.684)LPQT(0.132)ICR;GQS(0.14)T(0.05)DS(0.81)LPQTICR 177.88 0.0001319 44947000.0 45495.0 48366.0 75071.0 99603.0 88387.0 78624.0 67133.0 88828.0 71920.0 78221.0 True False 59961.463645213786 63999.36365132024 74075.50948948006 76641.06720100994 76115.99072067546 73707.62885088415 73107.70694614649 75101.673664375 75721.54437241006 75482.50659861944 0.7943756288335881 0.8478701428350655 0.9813599577896752 1.0153487298527484 1.0083924627122491 0.9764862373056415 0.9685384102955004 0.9949546861729232 1.0031667969780298 1.0 16.20385471183271 -5.185518811402324 2.8770386436281865 0.9945739730973361 0.8010979305914457 0.962850592488377 0.013749255957241418 0.05102392699204681 0.802997455405887 0.00418815569492127 0.0145550797183391 6.523507839069043e-06 5.185518811402324 -0.19347604250589034 GQSTDS(ph)LPQTICR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GQSTDSLPQTICR 13 0 Q96NE9-3;Q96NE9-2;Q96NE9 Q96NE9-3 FRMD6 FERM domain-containing protein 6 1 GQS(0.019)T(0.181)DS(0.403)LPQT(0.397)ICR;GQS(0.029)T(0.245)DS(0.726)LPQTICR;GQS(0.038)T(0.02)DS(0.942)LPQTICR 120.54 0.00021098 36484300.0 51954.0 65486.0 75612.0 77982.0 70101.0 64070.0 67268.0 59271.0 56437.0 55420.0 True False 60748.786061726096 71987.0172981032 77414.87684010691 73612.92136105508 56365.212274239144 60710.05641121111 60895.88806185435 57715.19905281557 57262.284356685755 65467.20729552141 0.927926951084133 1.0995889434102653 1.1824985368728693 1.1244243400938674 0.8609686376234819 0.9273353625298794 0.9301739080906268 0.8815894466413852 0.8746712548498009 1.0 15.998484817207578 -6.258673638107455 24.99800752303293 0.9081657252529636 1.091814562483511 0.5852784611313047 0.07039012126284344 169.61702339052064 1533073.595360766 0.021699478114284573 0.02675726541981892 5.51221770749659e-07 6.258673638107455 0.18364883723054737 GQSTDS(ph)LPQTICR ddPTM_PC-9_Lapatinib_30min_R1 2 GQSTDSLPQTICR 13 0 Q96NE9-3;Q96NE9-2;Q96NE9 Q96NE9-3 FRMD6 FERM domain-containing protein 6 1 GQSTDS(0.999)LPQTICR;GQS(0.001)T(0.044)DS(0.511)LPQT(0.444)ICR 196.97 9.0794e-07 54841000.0 59893.0 64225.0 69037.0 60616.0 55154.0 47364.0 40655.0 47414.0 63000.0 39667.0 True False 59038.91483696901 64076.290958472266 63361.04435052662 65073.90284904832 51909.9501569361 45338.35213087667 42759.91697355725 49617.027533316956 55904.27658058928 46523.38809704489 1.269015805852693 1.3772920154657076 1.3619181005983363 1.3987352493182184 1.1157818095417982 0.974528167129696 0.9191058244589309 1.0664964346495773 1.2016381193901107 1.0 15.505668545423667 -6.38854126271811 3.9735444651897405 1.03059292085023 1.3537615046887286 0.7974548045757037 0.07619194443894158 0.10845851120491845 2.9503422901758385 0.02605913229571549 0.029684532509046332 4.087509144658709e-07 6.38854126271811 0.32316858383849856 GQTGNS(ph)SRGPGDGGNR ddPTM_PC-9_Lapatinib_30min_R1 1 GQTGNSSRGPGDGGNR 16 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 GQT(0.074)GNS(0.767)S(0.16)RGPGDGGNR 53.49100000000001 0.035355000000000004 1562400.0 5021.4 3778.7 4555.7 3090.3 2377.4 3847.5 4761.4 3278.5 3607.7 3662.8 True False 4949.793915188016 3769.9506523126342 4181.147931510553 3317.5709709385947 2237.5660061482354 3682.9513939605613 5007.921994290872 3430.83107875268 3201.362835234793 4295.910099625788 1.152210777320314 0.8775673989641988 0.9732857146788915 0.7722626623931411 0.5208595976771365 0.8573157511562869 1.1657418051479027 0.7986272988002091 0.7452117853941265 1.0 12.068748087068014 -4.00246618689873 1.2866945611033196 0.8407025481864496 2.6022554998545333 0.2280548352660826 0.1630397581987308 14.187619944657467 4.674255141442019 0.050792493343396986 53.51740866116195 9.94337487612929e-05 4.00246618689873 1.7615529516680837 GQTPLTEGS(ph)EDLDGHSDPEESFAR ddPTM_PC-9_Lapatinib_30min_R1 1 GQTPLTEGSEDLDGHSDPEESFAR 24 0 K7EQI9;Q86VR2-2;Q86VR2 K7EQI9 FAM134C Protein FAM134C 1 GQT(0.014)PLT(0.062)EGS(0.576)EDLDGHS(0.32)DPEES(0.027)FAR 43.233000000000004 0.039449 9104600.0 6028.0 4445.7 4808.4 2471.1 2933.6 3210.4 2823.5 4580.6 3858.7 2197.6 True False 5942.039614600185 4435.406254792992 4413.071912960758 2652.8329373479464 2761.051415679509 3073.0986758079225 2969.687014508398 4793.431398302436 3424.092572087617 2577.4522318820655 2.305392721191688 1.7208490616930816 1.7121837830291489 1.0292462085362637 1.0712328172473553 1.192300923289637 1.152179263605565 1.8597556684114585 1.3284795464811898 1.0 11.331729974926487 -4.9665158991944205 1.3297464260857859 1.2687523364402986 2.4943321612619758 0.6208177855035095 0.25633809864763657 0.6950880521473337 1.3911870509562563 0.0819723369244139 1.0578682963741306 1.0801500766759506e-05 4.9665158991944205 1.2255798248216772 GQTPLTEGSEDLDGHS(ph)DPEESFAR ddPTM_PC-9_AZD4547_30min_R2 2 GQTPLTEGSEDLDGHSDPEESFAR 24 0 K7EQI9;Q86VR2-2;Q86VR2 K7EQI9 FAM134C Protein FAM134C 1 GQTPLTEGSEDLDGHS(0.988)DPEES(0.012)FAR;GQTPLTEGS(0.002)EDLDGHS(0.997)DPEES(0.001)FAR 155.68 1.8555e-07 24313000.0 12585.400000000001 11052.5 20764.1 27503.0 22448.1 17572.8 18145.3 20950.0 12903.2 17440.3 True False 16587.29540741782 14625.004481582468 20488.754466978062 21162.608267114192 19331.568797411353 16473.97003803946 19760.196547896143 17712.658883107302 13585.23680959511 16829.720405414177 0.9855954233251333 0.8689986600655324 1.2174150237449437 1.2574545362207035 1.1486565630164791 0.9788617779258965 1.1741250639873508 1.0524630508661974 0.8072170233573633 1.0 14.038723588714458 -8.096764635965192 6.334941579878705 0.9067714525829654 1.0924594537418881 0.27050024663235916 0.12067320725062514 0.3379189619959261 18.345086581763837 0.08866194395800464 0.03294251594542159 8.002678392355659e-09 8.096764635965192 0.1856880011589227 GQTPLTEGSEDLDGHS(ph)DPEESFAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GQTPLTEGSEDLDGHSDPEESFAR 24 0 K7EQI9;Q86VR2-2;Q86VR2 K7EQI9 FAM134C Protein FAM134C 1 GQTPLT(0.002)EGS(0.051)EDLDGHS(0.946)DPEES(0.001)FAR;GQTPLTEGSEDLDGHS(1)DPEESFAR 144.43 2.2412000000000002e-06 20154900.0 16432.0 18410.9 15910.3 16063.099999999999 22821.0 18208.8 18740.5 12763.2 14148.9 15416.7 True False 19213.613053206354 20238.612478600746 16289.661892148762 15163.136584272837 18349.388871919222 17253.898473239606 16965.264170529554 12428.179523728231 14355.800895411016 18211.62567146995 1.0550191070150374 1.11130180488534 0.8944650074632214 0.8326075254241126 1.0075645745709068 0.9474112187727038 0.9315623150055777 0.6824310881371796 0.7882767389569505 1.0 14.152572090633297 -4.249299590004705 0.46355205915016906 0.8480687444934665 1.4207862506663276 0.3225125582005308 0.10134524747347558 9.212638214916105 1.0585029321913457 0.07159820388507675 3.1994761444409403 5.6324897490588397e-05 4.249299590004705 0.5727175061728611 GQTPLTEGSEDLDGHS(ph)DPEESFAR ddPTM_PC-9_Lapatinib_30min_R1 1 GQTPLTEGSEDLDGHSDPEESFAR 24 0 K7EQI9;Q86VR2-2;Q86VR2 K7EQI9 FAM134C Protein FAM134C 1 GQTPLTEGSEDLDGHS(1)DPEESFAR 162.52 1.9541e-08 9594200.0 14771.0 11658.0 11701.0 7506.1 11408.0 11689.0 9875.1 8744.9 12059.0 6181.6 True False 14560.36283133035 11631.006617265386 10738.988947166177 8058.123633615574 10737.003868990952 11189.08871838986 10386.384358764604 9151.219978826995 10700.788433100422 7250.081323535756 2.0083033805515274 1.6042587797612617 1.4812232398420784 1.1114528615640062 1.480949439027075 1.5433052705308288 1.432588669736372 1.2622230800528569 1.475954262521542 1.0 12.823781462466036 -4.78265925800418 1.645240325991656 1.3601885454691318 2.2400318593584316 0.6025170086372569 0.16662509665996753 0.6931254413945771 1.8364463422752058 0.04554819623197618 0.9838609163599185 1.6494560264556972e-05 4.78265925800418 0.8798433138892998 GQVSES(ph)EDSITK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GQVSESEDSITK 12 0 O95239;O95239-2 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 GQVS(0.047)ES(0.818)EDS(0.126)IT(0.008)K 69.27600000000001 0.032529 11211000.0 16413.0 21912.0 17391.0 21907.0 21026.0 13000.0 20424.0 14170.0 15563.0 15612.0 True False 19191.396728473464 24087.278548636918 17805.66739573478 20679.621813452264 16906.10623640392 12318.25711480794 18489.29086304504 13798.052514356039 15790.579432696648 18442.332015476004 1.040616594060278 1.3060863739153985 0.9654780849186013 1.1213127383293406 0.9167011103702639 0.6679338114329031 1.002546253235742 0.748172872214713 0.8562138139279718 1.0 14.17073347427775 -6.349705096123759 3.93078924646714 0.8437300615676252 1.113344541253324 0.479352351539141 0.12466357575088123 0.18855734514571793 5.386643483866551 0.0379896802879039 0.04386799400742524 4.469870117499083e-07 6.349705096123759 0.26961447968569885 GQVSES(ph)EDSITK ddPTM_PC-9_Lapatinib_30min_R1 1 GQVSESEDSITK 12 0 O95239;O95239-2 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 GQVS(0.01)ES(0.772)EDS(0.157)IT(0.061)K 80.312 0.014431 13850000.0 33927.0 57822.0 44725.0 38684.0 51322.0 40083.0 55094.0 60501.0 42735.0 40710.0 True False 33443.19475855018 57688.116711573064 41047.883143492654 41528.95040604104 48303.34086293419 38368.74352803669 57946.49774298766 63312.09732975927 37921.734280499724 47746.66925733475 0.7004298996921696 1.2082123760436154 0.859701499224199 0.8697769090911288 1.0116588573456131 0.8035899493060987 1.213623874592803 1.3260002910052913 0.7942278460538745 1.0 15.543112475765366 -7.26451915103537 24.99723445815374 1.1106296913042815 0.9231571874850334 0.17320269234444086 0.18144151438787307 454.6464673045104 3690155.520561796 0.07097625366510958 0.05015026479297233 5.438521490040235e-08 7.26451915103537 -0.18747250381924807 GQVSESEDS(ph)ITK ddPTM_PC-9_AZD4547_30min_R2 4 GQVSESEDSITK 12 0 O95239;O95239-2 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 GQVSES(0.001)EDS(0.996)IT(0.003)K;GQVS(0.001)ES(0.004)EDS(0.974)IT(0.021)K;GQVS(0.012)ES(0.092)EDS(0.725)IT(0.172)K;GQVSES(0.156)EDS(0.842)IT(0.002)K 178.68 5.5048e-05 42599900.0 72835.0 96298.0 83515.0 85362.0 87695.0 90564.0 95475.0 97258.0 96543.0 83066.0 True False 95995.01493788649 127424.44528997321 82407.53653226842 65683.10972975327 75520.06297588612 84901.01876337327 103972.09004041727 82229.01086650352 101646.0658835593 80157.8846233226 1.1975742048207187 1.5896682639364215 1.0280652604483933 0.8194216955501121 0.9421414166649917 1.0591723966062674 1.2970912409802506 1.0258380850856224 1.2680732077850334 1.0 16.290556815680986 -5.28102078862068 24.56992322086659 1.0522526457790022 1.3936212349082664 0.4195382840578086 0.15930758881374132 546.0585428736883 685170.7703483586 0.0431518140263065 0.09005138075069431 5.235753737060591e-06 5.28102078862068 0.34136858912926415 GQVSESEDS(ph)ITK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GQVSESEDSITK 12 0 O95239;O95239-2 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 GQVS(0.005)ES(0.177)EDS(0.795)IT(0.022)K;GQVS(0.18)ES(0.006)EDS(0.811)IT(0.003)K;GQVSES(0.036)EDS(0.963)IT(0.001)K 138.19 6.8656e-05 18687100.0 62747.0 75672.0 62099.0 67773.0 67862.0 47047.0 77861.0 45842.0 51635.0 47433.0 True False 73368.82779025933 83184.21606117443 63579.675671769 63975.8985330306 54564.92825144315 44579.7724984899 70485.44241517565 44638.69607361392 52390.06419117722 56032.227420578616 1.309404090605786 1.4845780703449936 1.134698344125054 1.141769682879581 0.9738132992978862 0.7956095010086528 1.2579446804088479 0.796661102521506 0.9349987784340024 1.0 15.77396922397816 -5.660283137865934 1.3959655573696377 0.9579096795386379 1.4065170689354956 0.5958081621535691 0.1355459881210406 0.30322901576022565 1.1538914194825236 0.04349998005871786 0.11998538108049112 2.186335779721725e-06 5.660283137865934 0.4486073893968576 GQVSESEDS(ph)ITK ddPTM_PC-9_Lapatinib_30min_R1 1 GQVSESEDSITK 12 0 O95239;O95239-2 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 GQVSES(0.003)EDS(0.607)IT(0.39)K 155.06 0.00029953 14587000.0 20157.0 24464.0 22478.0 20491.0 26137.0 28591.0 27438.0 22644.0 24107.0 21804.0 True False 19869.557483658915 24407.355111063684 20629.945607589223 21997.97649597217 24599.673047319124 27368.22957887626 28858.605384834926 23696.12290598619 21391.81580203597 25572.792347996245 0.7769803630856055 0.9544266726498533 0.8067146257184418 0.8602101873202681 0.9619470847205558 1.0702088847571898 1.1284886293262433 0.9266146060049989 0.8365068433253096 1.0 14.642322079693265 -6.3260591377095015 3.8637126401206374 0.9976428328585973 0.8531374904253838 0.38957361561345705 0.0847850612608479 0.2651462181916996 7.89644151344504 0.02879968417186697 0.03367609385511047 4.719987650004898e-07 6.3260591377095015 -0.14450534243321356 GQVSESEDSIT(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GQVSESEDSITK 12 0 O95239;O95239-2 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 GQVSESEDS(0.046)IT(0.954)K 146.84 0.00031353 7609400.0 27622.0 38769.0 25531.0 22179.0 27443.0 18286.0 31106.0 21735.0 19732.0 14221.0 True False 32297.85904063205 42617.73010460499 26139.755866856696 20936.382535288176 22065.741151223865 17327.049969336764 28159.41449206222 21164.47928013609 20020.54317072351 16799.15472662593 1.9225883424623353 2.5368972902581666 1.5560161384445326 1.2462759511408583 1.313503060737373 1.0314239169351862 1.6762399626828113 1.2598538214896795 1.191758960288152 1.0 14.036101023125855 -5.4419908708169515 4.31944289014317 1.2742799715398698 2.221253352513584 0.7494664375456673 0.22397354305996334 0.10007372741887555 3.380983724536371 0.05730482165003021 0.12340962240420125 3.614174598152785e-06 5.4419908708169515 0.9469733809737142 GQVSESEDSIT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 2 GQVSESEDSITK 12 0 O95239;O95239-2 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 GQVS(0.003)ES(0.003)EDS(0.047)IT(0.946)K;GQVSESEDS(0.031)IT(0.969)K 179.83 0.00033074 26909000.0 51440.0 61751.0 60872.0 49137.0 58449.0 57627.0 67053.0 58004.0 58060.0 43955.0 True False 50706.456167059296 61608.019353470154 55867.339132715155 52750.698896226815 55011.14473515532 55162.42754509816 70524.6762471512 60699.077594012655 51520.67140109549 51552.56318364402 0.983587488878668 1.195052496885672 1.0836966327687867 1.0232410502716367 1.067088449883489 1.0700229850569183 1.3680149325635553 1.1774211376801247 0.9993813734840898 1.0 15.653756539449358 GQY(ph)HTLQAGFSSR ddPTM_PC-9_AZD4547_30min_R2 2 GQYHTLQAGFSSR 13 0 Q9Y446;Q9Y446-2;E9PK71;E9PQ15 Q9Y446 PKP3 Plakophilin-3 1 GQY(1)HTLQAGFSSR;GQY(1)HTLQAGFSSR 115.12 0.0028328000000000003 0.0 17568.0 28538.0 51426.0 82451.0 72732.0 63898.0 40561.0 72098.0 56359.0 66520.0 True False 23154.25856289958 37762.350408993465 50744.05763884854 63443.19580525146 62634.41724570558 59902.447958813944 44170.85042293132 60956.910747220434 59338.021680821104 64191.15504711225 0.3607079284662477 0.5882796528786293 0.790514792911977 0.9883479391933073 0.9757484064546881 0.9331885041615053 0.6881142797712972 0.94961542135333 0.9243956061745695 1.0 15.970086900436398 -5.087280713041868 1.7353777292999848 0.9131268222961679 0.32589161540100214 0.8179297846101948 0.08623241319216322 0.2253644086773388 1.0274729792880894 0.02591684797346098 0.18026801600957895 8.179359315330125e-06 5.087280713041868 -0.5872352068951658 down GRAEGEWEDQEALDY(ph)FSDKESGK ddPTM_PC-9_AZD4547_30min_R2 1 GRAEGEWEDQEALDYFSDKESGK 23 2 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 GRAEGEWEDQEALDY(0.816)FS(0.15)DKES(0.034)GK 96.37899999999999 1.7561e-05 11530000.0 66667.0 62912.0 60466.0 80922.0 81193.0 80369.0 75112.0 67532.0 65693.0 70077.0 True False 87865.7192402565 83247.07368878687 59664.18133221748 62266.68313243699 69920.75344319666 75343.51372502913 81796.8224887752 57096.4811309786 69165.39786508237 67623.62555977885 1.2993346410062525 1.231035351915537 0.8822978779727615 0.92078297513631 1.0339693097553186 1.1141596313617634 1.20958942694469 0.844327417501531 1.022799314478349 1.0 16.045239746222848 -5.119067099693575 5.622616715722006 1.0079559635151172 1.2827737222945004 0.5171492007553093 0.10184266571744906 0.17991980991336184 7.399326346018205 0.027858193341516006 0.0778406932320337 7.6020881351077115e-06 5.119067099693575 0.2748177587793832 GRAEGEWEDQEALDY(ph)FSDKESGK ddPTM_PC-9_Lapatinib_30min_R1 2 GRAEGEWEDQEALDYFSDKESGK 23 2 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 GRAEGEWEDQEALDY(0.521)FS(0.446)DKES(0.033)GK;GRAEGEWEDQEALDY(0.753)FS(0.232)DKES(0.014)GK 69.081 0.002412 17161700.0 62040.0 55669.0 61342.0 58340.0 59286.0 61868.0 51884.0 47495.0 53888.0 54486.0 True False 61155.298223257414 55540.101850793195 56298.69754696758 62630.51821653489 55798.91404076061 59222.04986135207 54570.29964963826 49701.79108902196 47818.56597420309 63903.8325019686 0.9569895236154026 0.8691200461111975 0.8809909412746608 0.9800745239278961 0.8731700722181519 0.9267370600899045 0.8539440830556945 0.7777591600236318 0.7482894859667455 1.0 15.96361483600782 -7.435629286688409 4.319047159572119 0.82100151153048 0.9116534993382953 0.16843790136308 0.07105950795631992 0.3128163050156637 10.372862778798943 0.03020252753753627 0.01939511932248908 3.6675049891188776e-08 7.435629286688409 0.09065198780781536 GRAEGEWEDQEALDYFS(ph)DKESGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GRAEGEWEDQEALDYFSDKESGK 23 2 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 GRAEGEWEDQEALDY(0.078)FS(0.461)DKES(0.461)GK 81.003 0.00019903 4791900.0 33729.0 23543.0 25661.0 37577.0 32243.0 28384.0 34313.0 34325.0 28626.0 27782.0 True False 39438.653521883985 25880.193449733448 26272.855559884425 35471.68251627772 25925.215608312144 26895.493072823723 31062.62423539288 33424.00512034375 29044.60109492864 32818.65667780901 1.2017144366713588 0.7885817418978289 0.8005463422166618 1.080838952810113 0.7899535883759068 0.8195184018914963 0.9464928604587429 1.0184452535177666 0.8850027403640723 1.0 15.00222856770255 -10.085253202959933 5.679619968592842 0.9999999987336866 0.9187547093537739 0.025212175162558026 0.13249154965592963 86851905.04558879 0.3999628217420996 0.6535931483055475 0.03112348304791344 8.217634046368923e-11 10.085253202959933 -0.08124528937991271 GRAEGEWEDQEALDYFS(ph)DKESGK ddPTM_PC-9_Lapatinib_30min_R1 2 GRAEGEWEDQEALDYFSDKESGK 23 2 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 GRAEGEWEDQEALDY(0.13)FS(0.833)DKES(0.037)GK;GRAEGEWEDQEALDY(0.119)FS(0.855)DKES(0.026)GK 90.45299999999999 6.3938e-06 19378800.0 115372.0 104920.0 89534.0 114032.0 98267.0 95366.0 89702.0 84299.0 95581.0 78245.0 True False 113726.77412336622 104677.06418626544 82172.86013123445 122418.29367960052 92487.12826035538 91287.41848900396 94346.33064474318 88215.8392886297 84815.66126744925 91769.54399509096 1.2392648930395669 1.140651458308052 0.8954262662090827 1.3339751768424288 1.0078194162684606 0.9947463451914635 1.0280788869321402 0.9612757724212799 0.9242245038504965 1.0 16.485727818400726 -6.493145051023885 24.959266994387704 0.9842720110195493 1.1378641221662111 0.36706738680155493 0.10674090084983837 817.7619287294154 686452.1947555377 0.032818135163478306 0.03715420127289016 3.2125873799075917e-07 6.493145051023885 0.15359211114666182 GRAEGEWEDQEALDYFSDKES(ph)GK ddPTM_PC-9_AZD4547_30min_R2 2 GRAEGEWEDQEALDYFSDKESGK 23 2 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 GRAEGEWEDQEALDY(0.292)FS(0.32)DKES(0.388)GK;GRAEGEWEDQEALDY(0.243)FS(0.275)DKES(0.482)GK 47.808 0.014359 23853000.0 38084.0 35806.0 36206.7 51035.0 44440.0 44266.0 44649.0 44372.0 40807.0 40734.0 True False 50193.919803589895 47379.589275507045 35726.57550096247 39269.66923288997 38270.27309023748 41498.04002229894 48622.67450342594 37515.32696712349 42963.97471085839 39307.91505846465 1.276941799862291 1.2053447557581467 0.9088901166043666 0.9990270197359034 0.9736022130229032 1.0557171490926651 1.2369690539706055 0.9543962561058007 1.0930107752333316 1.0 15.26253222297097 -5.083511544042887 5.8990277521312615 1.0319797604276637 1.2608074837497383 0.5050447262246265 0.08567606496011161 0.16782008519682692 9.196420743573533 0.022621436463715398 0.06334856294593386 8.25065554003449e-06 5.083511544042887 0.22882772332207457 GRAEGEWEDQEALDYFSDKES(ph)GK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GRAEGEWEDQEALDYFSDKESGK 23 2 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 GRAEGEWEDQEALDY(0.264)FS(0.323)DKES(0.413)GK 69.248 0.00037935 5010700.0 26629.0 20107.0 19040.0 32790.0 25463.0 27279.0 26017.0 29888.0 23299.0 20543.0 True False 31136.76375327607 22103.090077466346 19493.98580960211 30952.88260661433 20473.707937674935 25848.44121806507 23552.481413231617 29103.471668953633 23639.703797622515 24267.28328170147 1.2830757935213322 0.9108184802100606 0.8033031791532007 1.275498466280899 0.8436753179171462 1.0651559516575906 0.9705446275064155 1.1992884135859925 0.9741388652040759 1.0 14.56672498761013 GRAS(ph)PGGVSTSSSDGK ddPTM_PC-9_AZD4547_30min_R2 4 GRASPGGVSTSSSDGK 16 1 P54259 P54259 ATN1 Atrophin-1 1 GRAS(1)PGGVSTSSSDGK;GRAS(0.962)PGGVS(0.001)T(0.026)S(0.006)S(0.002)S(0.002)DGK;GRAS(0.973)PGGVS(0.008)T(0.019)SSSDGK;GRAS(0.998)PGGVS(0.001)TSSSDGK 170.0 0.00015027 42604600.0 52588.0 53534.0 71028.0 82400.0 84166.0 74827.0 61931.0 86920.0 67614.0 66977.0 True False 69309.89010164863 70837.81858557218 70086.12231112923 63403.95306730942 72481.00371091215 70148.0558611252 67442.73902375586 73488.51122289675 71187.93800328321 64632.15561621211 1.0723747249467133 1.0960151013097799 1.0843847252643555 0.9809970356521017 1.1214387485589488 1.085342971966875 1.043485837362954 1.1370270807502378 1.1014322100905864 1.0 15.979964488834463 GRAS(ph)PGGVSTSSSDGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GRASPGGVSTSSSDGK 16 1 P54259 P54259 ATN1 Atrophin-1 1 GRAS(1)PGGVSTSSSDGK;GRAS(1)PGGVSTSSSDGK 144.17 0.00014135 29355000.0 53103.0 51877.0 55801.0 61460.0 70408.0 52485.0 54341.0 46455.0 44544.0 49129.0 True False 62092.289067941674 57027.005716850945 57131.50746647093 58016.595456008465 56612.05782805703 49732.59420543803 49193.42708522966 45235.60547314113 45195.371731031264 58035.69879504998 1.0698981895129294 0.9826194377057269 0.9844200837182618 0.9996708346855789 0.975469564482708 0.8569310827300636 0.8476408160252134 0.7794444869680692 0.778751228457442 1.0 15.824652980329132 -6.746109749138619 2.5607086978201443 0.833519795624181 1.0053860338247158 0.5878877440715798 0.06247997630635524 0.18309162756912145 2.461060421185936 0.02268951240185579 0.021210495330047967 1.7942801428671134e-07 6.746109749138619 0.17186623820053482 GRAS(ph)PGGVSTSSSDGK ddPTM_PC-9_Lapatinib_30min_R1 1 GRASPGGVSTSSSDGK 16 1 P54259 P54259 ATN1 Atrophin-1 1 GRAS(0.999)PGGVSTSSSDGK 142.58 0.00012908 21702000.0 15328.0 17880.0 17349.0 19295.0 20489.0 18068.0 17247.0 18170.0 17094.0 16129.0 True False 15109.419909189057 17838.599958543924 15922.63218907667 20714.018666233118 19283.877302923876 17295.273758565145 18139.965269780885 19014.244532846176 15168.693712199898 18916.87615945841 0.7987270087209599 0.9429992461849812 0.8417157280545698 1.09500207601011 1.0194007266512641 0.9142774743977765 0.9589302756370232 1.0051471697846412 0.8018603909195426 1.0 14.207386248282324 -4.151141757332726 1.1581763297445586 0.962707923624869 0.3719895183406931 0.24940484878394353 0.0812058772854458 8.384206892847384 3.3684882822624393 0.024386332815506777 8.564730560838148 7.060870439581579e-05 4.151141757332726 -0.5907184052841759 GRAS(ph)PGGVSTSSSDGKAEK ddPTM_PC-9_AZD4547_30min_R2 1 GRASPGGVSTSSSDGKAEK 19 2 P54259 P54259 ATN1 Atrophin-1 1 GRAS(0.994)PGGVS(0.001)T(0.001)S(0.001)SS(0.003)DGKAEK 48.376000000000005 0.02331 3938200.0 12552.0 6305.4 12589.0 24823.0 22703.0 13478.0 9122.8 12576.0 10050.0 17819.0 True False 16543.274902180987 8343.497241182544 12422.061634493528 19100.44086152695 19551.080332305617 12635.218529357628 9934.711526794641 10632.668167730657 10581.222482518358 17195.162233681476 0.9620889106690957 0.4852235255355427 0.7224160764334917 1.1108031783563785 1.1370105188079833 0.7348124058177282 0.5777620118834799 0.618352303004367 0.615360433284666 1.0 14.069715107081707 -6.987229809331887 24.99196420245512 0.6689535939207244 0.8721446268947285 0.14234525898531214 0.20752559882848512 438.49340513239565 858152.3094501245 0.07840713448918576 0.06910926350186522 1.0298410301472497e-07 6.987229809331887 0.2031910329740041 GRAS(ph)PGGVSTSSSDGKAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GRASPGGVSTSSSDGKAEK 19 2 P54259 P54259 ATN1 Atrophin-1 1 GRAS(0.998)PGGVSTS(0.001)SS(0.001)DGKAEK;GRAS(0.995)PGGVS(0.001)T(0.001)SSS(0.001)DGKAEK;GRAS(0.997)PGGVSTS(0.001)S(0.001)S(0.001)DGKAEK;GRAS(1)PGGVSTSSSDGKAEK 50.831 0.018004 22357600.0 89349.0 49517.1 62517.8 118960.0 111783.0 131698.0 106097.0 141388.0 127227.0 94999.0 True False 104474.02097680933 54432.83044088671 64008.461452076815 112295.05687352364 89879.92359097963 124791.5250389213 96046.72408423861 137676.71481296874 129087.45418516318 112221.56668832988 0.9309620606791419 0.48504785708491877 0.5703757605687853 1.0006548668617135 0.8009148886737686 1.1120101841520502 0.8558668972336373 1.2268293775949037 1.1502909645137507 1.0 16.775990433488317 -6.330766805310818 0.9762808583575201 1.0906390899698788 0.6533485226875766 0.4823400328561672 0.1650646724160844 0.45132870313859974 0.9175021455512444 0.0789127311517029 0.11468402029722798 4.6691002064029625e-07 6.330766805310818 -0.4372905672823022 GRAS(ph)PGGVSTSSSDGKAEK ddPTM_PC-9_Lapatinib_30min_R1 3 GRASPGGVSTSSSDGKAEK 19 2 P54259 P54259 ATN1 Atrophin-1 1 GRAS(0.949)PGGVS(0.029)T(0.013)S(0.002)S(0.005)S(0.002)DGKAEK;GRAS(0.997)PGGVS(0.001)TSSS(0.001)DGKAEK;GRAS(0.97)PGGVS(0.011)T(0.003)S(0.003)S(0.001)S(0.011)DGKAEK 50.88399999999999 0.017889 24298800.0 148216.0 57821.0 70652.0 62990.0 64075.0 61468.0 44434.0 46758.0 75513.0 44830.0 True False 146102.41266051467 57687.11902701166 64843.265284606845 67622.49472848012 60306.234476296864 58839.15692890648 46734.57510276821 48930.54737847118 67007.93075285772 52578.80576777984 2.778732048532868 1.097155368682074 1.2332586169985364 1.2861169770029088 1.1469685093770687 1.119066058456637 0.888848166487019 0.9306135174423398 1.2744285415839554 1.0 15.682193753676044 -4.761162560455152 24.999988310727122 1.1104448635116342 2.778733904090454 0.9372610407706546 0.1296387260859339 1.5842149227839992 142822.53902191517 0.034968636143613986 0.19795658133461835 1.7331551402710527e-05 4.761162560455152 1.6682890405788198 GRAS(ph)SHSSQTQGGGSVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GRASSHSSQTQGGGSVTK 18 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 GRAS(0.843)S(0.157)HSSQTQGGGSVTK 83.89399999999999 0.00095014 1383500.0 0.0 0.0 1167.0 1118.6 2262.3 2999.1 985.96 547.54 1077.4 529.81 True False 0.0 0.0 1194.8257058721463 1055.928468550131 1819.0185550564336 2841.82191638619 892.5627310677575 533.1676551665845 1093.1549367594534 625.8603590263476 0.0 0.0 1.9090931205979227 1.6871630441538767 2.9064287725240896 4.540664503511963 1.4261371857075584 0.8518955506241594 1.7466435139942031 1.0 9.289696991001042 -5.289696061291514 4.171260509459009 2.1107438345347225 6.230996641657049e-15 0.3866464362784823 1.0074709492504705 0.21858278665805939 8.934558424854744 0.2929733358789396 0.713484305519805 5.132204329575739e-06 5.289696061291514 -2.1107438345347163 GRASS(ph)HSSQTQGGGSVTK ddPTM_PC-9_AZD4547_30min_R2 4 GRASSHSSQTQGGGSVTK 18 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 GRAS(0.181)S(0.789)HS(0.02)S(0.007)QT(0.003)QGGGSVTK;GRAS(0.169)S(0.83)HS(0.001)SQTQGGGSVTK;GRAS(0.372)S(0.627)HS(0.001)SQTQGGGSVTK;GRAS(0.407)S(0.576)HS(0.016)S(0.001)QTQGGGSVTK 120.32 3.7699e-05 7831000.0 1068.5 1920.8600000000001 7624.35 45582.200000000004 23978.0 10417.88 4624.84 22072.3 3401.31 13930.759999999998 True False 1408.260773819342 2541.740430535399 7523.246137338212 35073.92802796977 20649.068590407624 9766.44831671051 5036.441800497759 18661.53320599567 3581.096302688009 13443.048332593344 0.10475754746822885 0.18907470743617144 0.5596384057548707 2.6090754983697617 1.5360406419385493 0.7265054826167118 0.3746502784109355 1.388192078484896 0.26639019767603317 1.0 13.714572698890501 -5.531668130705644 24.999998662360365 1.1498717006141825 0.2037758413431326 0.28948777130231385 0.6267717147157269 244.64061364126434 695838.8654635368 0.18147217777860303 0.3149107809600319 2.9398953362773025e-06 5.531668130705644 -0.94609585927105 GRASS(ph)HSSQTQGGGSVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GRASSHSSQTQGGGSVTK 18 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 GRAS(0.4)S(0.547)HS(0.039)S(0.013)QT(0.001)QGGGSVTK;GRAS(0.377)S(0.557)HS(0.046)S(0.018)QT(0.002)QGGGSVTK;GRAS(0.333)S(0.624)HS(0.039)S(0.003)QT(0.001)QGGGSVTK 62.303000000000004 0.009964399999999998 3454440.0 462.66 1479.87 8816.9 7199.9 13055.9 12749.4 7537.700000000001 6948.7 9704.3 6784.7 True False 540.9792000484699 1626.7817134798877 9027.12833427946 6796.5129453907475 10497.690117562348 12080.79901996403 6823.674487777837 6766.303987756231 9846.207028768107 8014.712402344351 0.06749826729780475 0.20297443399267132 1.1263196832414062 0.8480045950747687 1.309802472075194 1.507327825815724 0.851393555404667 0.8442354070967097 1.2285165748290647 1.0 12.968435036713046 -5.231871240954759 4.878035726954363 1.0916179563935005 0.10874738611260339 0.7711763775719254 0.20812511045428522 0.09029686168896174 5.765263434544255 0.05742130893923456 0.15287294064137125 5.863119677337396e-06 5.231871240954759 -0.9828705702808971 down GRASS(ph)HSSQTQGGGSVTK ddPTM_PC-9_Lapatinib_30min_R1 1 GRASSHSSQTQGGGSVTK 18 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 GRAS(0.189)S(0.806)HS(0.005)S(0.001)QTQGGGSVTK 86.70700000000001 0.00080975 1086300.0 3313.0 455.18 4144.7 644.65 763.79 2695.7 1207.6 909.46 3142.9 815.91 True False 3265.7560124702086 454.12605867617566 3803.9387650046738 692.059711489359 718.8653738689162 2580.41119498362 1270.1236191678206 951.7168317469618 2788.91350579578 956.9389563682629 3.412710905682299 0.47456115738004545 3.975111201911178 0.7232015238629607 0.7512134071718909 2.6965264375657725 1.327277576814454 0.9945428863706 2.914411088853729 1.0 9.902283087157231 -4.730431516062633 24.529955994604638 1.6887003987525369 3.4127249291119597 0.18666358101304192 1.1008064673032967 5703.502802100569 4511654.810109299 0.26005152478785626 34.64177082388396 1.860237881180327e-05 4.730431516062633 1.7240245303594228 GRDGY(ph)SGPPRREPLPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GRDGYSGPPRREPLPPR 17 3 O75526 O75526 RBMXL2 RNA-binding motif protein, X-linked-like-2 1 GRDGY(0.703)S(0.297)GPPRREPLPPR 50.158 0.04095 10345000.0 11506.0 15779.0 17319.0 22349.0 24010.0 25256.0 20750.0 20096.0 22991.0 18597.0 True False 13453.738546141207 17345.434840221886 17731.950642673248 21096.857986435618 19305.412857227144 23931.53089935303 18784.409783009432 19568.501293472058 23327.199880301254 21968.488886229003 0.6124107404845088 0.7895597612585411 0.8071538618110671 0.9603235841888166 0.8787774597154375 1.089357170777211 0.855061532920659 0.8907531781004117 1.0618481772282464 1.0 14.423148016205461 -4.113709408538032 0.6243700616109642 0.9686189682976505 3.7524752099728455e-14 0.6960161034343351 0.0742725449802667 4.173991394373641 0.6700789412171603 0.033500076334614194 3.4912139195508107 7.69645246574089e-05 4.113709408538032 -0.968618968297613 GRDS(ph)PYQSR ddPTM_PC-9_AZD4547_30min_R2 5 GRDSPYQSR 9 1 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 1 GRDS(1)PYQSR;GRDS(1)PYQSR;GRDS(1)PYQSR;GRDS(1)PYQSR;GRDS(0.909)PYQS(0.091)R 74.237 0.013080000000000001 1572121700.0 13577.05 12279.029999999999 19016.07 25990.299999999996 16541.6 19607.28 16296.17 21463.099999999995 16228.070000000002 9559.48 True False 17894.269479816467 16247.986317981035 18763.904486920575 19998.637881132167 14245.084368800017 18381.233682022805 17746.4975601356 18146.471067972314 17085.852649938486 9224.805514879257 1.9397991048107948 1.7613364630586148 2.0340704697410823 2.1679197300013677 1.5442151431619064 1.9925876651138694 1.9237801308126423 1.9671386067384025 1.8521639965611916 1.0 13.171302780043582 -8.704951432109459 6.266808796481424 1.0000001481281795 1.9137164325499254 0.7503704398800904 0.1577070657930369 4.944832324277058 170.30199758630178 0.15011044865824244 0.03888236467030272 1.972643327838392e-09 8.704951432109459 0.9137162844217459 GRDS(ph)PYQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GRDSPYQSR 9 1 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 1 GRDS(0.999)PYQSR;GRDS(0.982)PYQS(0.018)R;GRDS(0.997)PYQS(0.003)R;GRDS(1)PYQSR 69.26100000000001 0.01927 1861227400.0 61506.4 59868.700000000004 62659.2 63611.95 56250.96000000001 76256.72 85565.42 89723.44 66009.02 48209.4 True False 71918.21871322622 65812.06887754564 64153.23296433932 60047.97867422445 45228.98818889507 72257.6833609166 77460.04397760547 87368.29476984298 66974.27704070318 56949.38259459959 1.2628445724369644 1.1556239221421598 1.1264956710948233 1.0544096518426294 0.7941962867422562 1.268805385921228 1.360155992015107 1.534139454887224 1.176031661615489 1.0 15.79739258087638 -6.974460271226653 24.99969996466023 1.3124345824163257 1.0790120016164348 0.21833030277783672 0.1706737457516394 284.24284712719066 278231.7908476997 0.06047519046024183 0.05333253447072619 1.0605709537791952e-07 6.974460271226653 -0.23342258079989087 GRDS(ph)PYQSR ddPTM_PC-9_Lapatinib_30min_R1 2 GRDSPYQSR 9 1 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 1 GRDS(1)PYQSR;GRDS(0.997)PY(0.002)QS(0.001)R 77.387 0.010915000000000001 9724200.0 3245.19 1709.41 1729.12 3288.2 1377.72 2117.6 1716.92 2073.81 2139.2 3263.42 True False 3198.9129955050403 1705.4519661708368 1586.958428196221 3530.025197113643 1296.6852183017363 2027.0351843667006 1805.8137166459203 2170.1667834156146 1898.2607692253428 3827.497798766184 0.8357713481993976 0.44557882351247835 0.4146203372625808 0.9222801377577714 0.33878144063720433 0.5295980013417975 0.47180006667228774 0.5669936071851381 0.4959534581149225 1.0 11.902185832678457 -10.581184529776168 5.085677935953723 1.0000059345596466 0.5515818846625321 0.3663071920574894 0.1742528226722517 1.3759727804469969e-05 2.548148565649208e-06 0.16125604757043552 0.03910970134589511 2.623103761552997e-11 10.581184529776168 -0.4484240498971145 GRDSPYQSR ddPTM_PC-9_AZD4547_30min_R2 1 GRDSPYQSR 9 1 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 0 112.11 0.0028391 2470600.0 10547.0 9429.5 14252.0 11605.0 11685.0 12536.0 12709.0 15939.0 14250.0 8578.1 False True 13900.726608771738 12477.401471077288 14063.009167908625 8929.646545462692 10062.739447781838 11752.121938271794 13840.076379404687 13475.993791782676 15003.225908048413 8277.783329970433 1.6792812827611652 1.507336079443125 1.6988858740711756 1.0787485235488266 1.2156321380566724 1.4197184765300894 1.671954414329195 1.6279713124396082 1.8124690282394722 1.0 13.015028771347213 -7.236465844331358 22.065917971433013 1.5804296014921044 1.4227003649832326 0.013797757155336043 0.2668037221373035 517.9488659932257 457644.4462381495 0.1027564529131695 0.07953027150801198 5.801417967537911e-08 7.236465844331358 -0.15772923650887183 GRDVESVQT(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 3 GRDVESVQTPSK 12 1 P46013 P46013 MKI67 Antigen KI-67 1 GRDVESVQT(0.964)PS(0.035)K;GRDVESVQT(0.928)PS(0.072)K;GRDVESVQT(0.757)PS(0.243)K 85.988 0.006751600000000001 27266200.0 105975.0 113252.0 139978.0 195740.0 154242.0 172655.0 108783.0 139279.0 129973.0 157978.0 True False 139672.8455830651 149858.49423643324 138121.80025999964 150615.16715285348 132828.16071072023 161858.85555618332 118464.4762594051 117756.63086302164 136843.1074348615 152447.23830476103 0.9162044989220576 0.9830187539169941 0.9060301898278862 0.9879822607986836 0.8713057854493905 1.061736882583647 0.7770850923686781 0.7724418767600857 0.8976424168556932 1.0 17.21795048952626 -7.276694184660306 24.99973430482918 0.8428291745915778 0.951235101549623 0.23758830907813655 0.07823959958597815 989.5951797192658 1621752.6053813451 0.030781841531121217 0.020839742430284563 5.2881749591647636e-08 7.276694184660306 0.10840592695804518 GRDVESVQT(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GRDVESVQTPSK 12 1 P46013 P46013 MKI67 Antigen KI-67 1 GRDVES(0.007)VQT(0.956)PS(0.037)K;GRDVESVQT(0.981)PS(0.019)K 90.853 0.0048457 13941900.0 93657.0 76956.0 93063.0 105939.0 138201.0 98217.0 117562.0 105115.0 104036.0 80604.0 True False 109511.2802899313 84595.68309551399 95281.97486339293 100003.58128887229 111121.50613417933 93066.32761885316 106425.6762848265 102355.84262854852 105557.32968322486 95216.86713908687 1.1501248001571407 0.8884527042035723 1.0006837835171678 1.0502717038861746 1.1670359409311373 0.9774143007972281 1.1177187349523536 1.0749759544076731 1.1085990629058744 1.0 16.538929541133705 -5.881296906449366 4.548843396220949 1.0778674311184844 1.0010948493394136 0.10015180581458227 0.07853369192367424 0.3832981859914508 13.461675961098685 0.021347312674333357 0.03262408291476092 1.314325982911319e-06 5.881296906449366 -0.07677258177907076 GRDVESVQT(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 1 GRDVESVQTPSK 12 1 P46013 P46013 MKI67 Antigen KI-67 1 GRDVESVQT(0.995)PS(0.005)K 73.296 0.016576 8176100.0 56795.0 47421.0 60030.0 42666.0 49086.0 46258.0 37440.0 38268.0 43085.0 37964.0 True False 55985.09288507258 47311.19958803757 55094.565122501095 45803.79996960362 46198.85798678907 44279.65317266476 39378.46000467304 40046.070984202415 38232.313594836334 44526.026816149744 1.2573565819433634 1.0625515674997894 1.2373564196506772 1.028697219240555 1.0375697382015812 0.9944667498741292 0.8843919572538715 0.8993856817621456 0.8586509133792585 1.0 15.442361261297139 -6.346116193913116 0.8855113923804909 0.9001569315202466 1.1878469793365531 0.7233681710190192 0.06764945101240463 0.30175243919266614 0.5123783978769547 0.033537354523013756 0.04961602530653826 4.506961063011461e-07 6.346116193913116 0.2876900478163066 GRDWNVDLIPK ddPTM_PC-9_Lapatinib_30min_R1 1 GRDWNVDLIPK 11 1 P50395;P50395-2;Q5SX87;V9GYJ7;V9GYF8;Q5SX90;Q5SX86;P31150;G5E9U5 P50395 GDI2;GDI1 Rab GDP dissociation inhibitor beta;Rab GDP dissociation inhibitor alpha 0 112.84 0.0021219999999999998 3286500.0 57677.0 47909.0 53817.0 48697.0 48205.0 51008.0 48061.0 37428.0 52536.0 37321.0 False True 56854.51540333359 47798.06965402021 49392.3739996276 52278.33982842987 45369.67667467641 48826.50674545557 50549.36341572091 39167.041517631624 46618.84245139428 43771.88512289343 1.2988820390922056 1.091981063182975 1.1284040854295891 1.1943360374279932 1.0365026899640497 1.1154764435749305 1.1548363355564677 0.8947990566928223 1.0650407749291073 1.0 15.417716897382595 -1.522878745280353 0.1852233967396846 0.9712039613876075 2.1223420867371705 0.47008515393501316 0.07631133519142935 51.61631998848799 0.5930962878865679 0.16377690295379674 16.856903111814997 0.029999999999998937 1.522878745280353 1.1511381253495632 GRECS(ph)PTSSLER ddPTM_PC-9_AZD4547_30min_R2 1 GRECSPTSSLER 12 1 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 GRECS(0.907)PT(0.072)S(0.011)S(0.011)LER 99.161 0.016566 13649000.0 11889.0 11616.0 16399.0 22820.0 21244.0 19644.0 14472.0 21299.0 15513.0 14644.0 True False 15669.454693437681 15370.644836739368 16181.53854508375 17559.201565485444 18294.637298132442 18415.65757461798 15759.979964021139 18007.72895232947 16332.985509582817 14131.3180172867 1.1088459458820044 1.0877007238770378 1.1450834610960587 1.2425735196112244 1.2946164877014865 1.3031804642773088 1.1152519492337596 1.2743134738246493 1.1558005763937123 1.0 13.786608410566311 -5.564872281044901 4.259972208538743 1.2140359780149304 1.100994833525767 0.15533137323891677 0.08842681862960695 0.2951587111973879 11.68084900761044 0.023376285296982817 0.043879859440302975 2.7235021280699805e-06 5.564872281044901 -0.11304114448916325 GREDVSNFDDEFTSEAPILT(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GREDVSNFDDEFTSEAPILTPPR 23 1 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 GREDVSNFDDEFT(0.005)S(0.005)EAPILT(0.99)PPR 60.912 0.034367 0.0 3888.5 5636.0 4213.1 4309.4 5046.3 3005.2 5311.8 3078.3 3456.8 3237.8 True False 4546.746248624203 6195.504832973605 4313.556282270727 4067.9582892633066 4057.513740167655 2847.602021647753 4808.627849898287 2997.497886728453 3507.349160376904 3824.787509589304 1.1887578688292728 1.619829812098205 1.1277897847804637 1.0635775919745443 1.0608468392021444 0.7445124767084176 1.2572274506341465 0.7837031153268739 0.9170049712783951 1.0 11.901163884133467 -5.556886384609417 2.701559559319769 0.9686459466873912 1.40500465082047 0.4925206436718439 0.17018933712405918 0.20578124819951318 3.0155271517824183 0.04596229679621308 0.0988548289388654 2.7740457253517946e-06 5.556886384609417 0.43635870413307887 GREDVSNFDDEFTSEAPILT(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 1 GREDVSNFDDEFTSEAPILTPPR 23 1 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 GREDVSNFDDEFT(0.004)S(0.003)EAPILT(0.993)PPR 75.512 0.0038122 0.0 4160.7 4192.9 5142.1 3532.1 3850.6 4303.3 5114.0 3926.7 4769.3 3924.4 True False 4101.367655021066 4183.191597661007 4719.3363870800085 3791.8624167401927 3624.1152785708764 4119.257890482255 5378.777897005824 4109.1488171231185 4232.13121104452 4602.727311065698 0.8910733523493163 0.9088506259330073 1.0253347783028475 0.8238294733698311 0.7873843123093387 0.8949602294663199 1.1686066832754518 0.8927639070087995 0.9194833682346973 1.0 12.168273257176807 -7.044675950633699 24.999289417350674 0.9927780624819728 0.8874886607932247 0.2548257469403834 0.08937947873304783 698.6921516935236 390964.63249626494 0.035701509790339064 0.027655709755414756 9.022440970619902e-08 7.044675950633699 -0.10528940168874801 GREDVSNFDDEFTSEAPILT(ph)PPREPR ddPTM_PC-9_AZD4547_30min_R2 6 GREDVSNFDDEFTSEAPILTPPREPR 26 2 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 GREDVSNFDDEFTSEAPILT(1)PPREPR;GREDVSNFDDEFTSEAPILT(1)PPREPR;GREDVSNFDDEFTSEAPILT(1)PPREPR;GREDVSNFDDEFTSEAPILT(1)PPREPR;GREDVSNFDDEFT(0.001)S(0.001)EAPILT(0.998)PPREPR;GREDVSNFDDEFT(0.001)S(0.001)EAPILT(0.998)PPREPR 119.94 4.9009e-11 281002200.0 40770.399999999994 46032.5 59942.9 83813.2 72549.29999999999 61205.5 56372.100000000006 70888.2 55955.200000000004 55343.7 True False 53734.539122998685 60911.605410399854 59148.01798000495 64491.36164103175 62477.08198707397 57378.310409452344 61389.10769277201 59934.057538782195 58912.87763719515 53406.13390831127 1.0061492040455733 1.140535757839617 1.1075135691632625 1.2075646919462812 1.169848431536645 1.0743767842840035 1.1494767211228223 1.1222317204551484 1.1031106977025893 1.0 15.70471783028045 -10.646270314295885 8.438525542353156 0.9999999950348781 1.123940306195165 0.32185696156486787 0.05202502029006364 4.854032639918208e-09 5.325198087529947e-10 0.05026098051696649 0.012190077779682567 2.258029886011635e-11 10.646270314295885 0.12394031116028681 GREDVSNFDDEFTSEAPILT(ph)PPREPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 GREDVSNFDDEFTSEAPILTPPREPR 26 2 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 GREDVSNFDDEFTS(0.001)EAPILT(0.999)PPREPR;GREDVSNFDDEFTSEAPILT(1)PPREPR;GREDVSNFDDEFTSEAPILT(1)PPREPR;GREDVSNFDDEFTS(0.001)EAPILT(0.999)PPREPR;GREDVSNFDDEFT(0.001)S(0.001)EAPILT(0.997)PPREPR;GREDVSNFDDEFT(0.001)S(0.001)EAPILT(0.998)PPREPR;GREDVSNFDDEFTSEAPILT(1)PPREPR;GREDVSNFDDEFTSEAPILT(1)PPREPR 101.48 9.7564e-10 329690900.0 68946.0 72569.2 83096.3 90734.0 103668.1 82405.1 81729.3 87185.4 73447.59999999999 62227.7 True False 80617.1960544284 79773.39058286519 85077.63093647275 85650.46814359697 83355.07999268269 78083.63149011222 73987.30903510904 84896.87563056697 74521.6322007924 73509.08941579796 1.0966969757770229 1.085218048772632 1.1573756607871757 1.1651684005922358 1.1339424913998282 1.0622309718521847 1.0065055848618403 1.1549167090120644 1.0137743888958695 1.0 16.16563503010164 -6.7910418377091775 6.217950838637198 1.0540731990554022 1.1291476519608286 0.4178756714463615 0.047030795217971294 0.19685469075039427 22.89015837614017 0.016610286650296763 0.014994823977484112 1.6179241675959289e-07 6.7910418377091775 0.07507445290542636 GREDVSNFDDEFTSEAPILT(ph)PPREPR ddPTM_PC-9_Lapatinib_30min_R1 3 GREDVSNFDDEFTSEAPILTPPREPR 26 2 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 GREDVSNFDDEFTSEAPILT(1)PPREPR;GREDVSNFDDEFT(0.007)S(0.006)EAPILT(0.986)PPREPR;GREDVSNFDDEFTSEAPILT(1)PPREPR 118.76 6.051899999999999e-11 70343000.0 40442.5 35429.6 45527.1 35784.6 35329.6 39677.4 33170.5 37488.1 39379.1 31649.8 True False 39865.782533753816 35347.56493798812 41784.037577688185 38416.31885792619 33251.58238866609 37980.4900945369 34887.906185497 39229.933983037474 34943.81107769339 37120.425759292404 1.073958116543805 0.9522402886001252 1.1256346532401593 1.0349105128006078 0.8957758891098434 1.0231695708670365 0.9398573823405962 1.0568287723159262 0.9413634235848133 1.0 15.179925637355915 -6.026389237594096 24.94260202764492 0.978251233184884 1.0473570600572701 0.26082753816625626 0.05846731928795853 1002.1439808400264 947206.6427890103 0.0164295952828303 0.02129106772166948 9.41045803628304e-07 6.026389237594096 0.06910582687238609 GRES(ph)PAAGPR ddPTM_PC-9_AZD4547_30min_R2 2 GRESPAAGPR 10 1 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 GRES(1)PAAGPR;GRES(1)PAAGPR 61.235 0.030547 62947000.0 28612.0 24241.0 30811.0 30658.0 30551.0 35754.0 21122.0 35875.0 26005.0 26865.8 True False 37710.02083342912 32076.4291914083 30402.426008450235 23590.271761378302 26309.520998646407 33518.29672790122 23001.81708126413 30331.343075488017 27379.571209740287 25925.236519313108 1.4545680540016246 1.2372665980313367 1.1726961868140269 0.9099346786597158 1.0148227955045666 1.2928829676416504 0.8872365374228633 1.1699543436331838 1.0560972583352815 1.0 14.662069530542958 -4.926643240675459 1.5928859977872838 1.0587113910087267 1.5280583997173387 0.5423114718540485 0.11494946974634876 0.5990386141269526 1.8228175804716502 0.032224483454612055 0.40477516750173564 1.1840137866108707e-05 4.926643240675459 0.469347008708612 GRES(ph)PAAGPR ddPTM_PC-9_Lapatinib_30min_R1 1 GRESPAAGPR 10 1 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 GRES(1)PAAGPR 63.662 0.025564 14236000.0 6183.2 8494.2 6764.3 6915.9 2889.6 8239.9 9002.2 7570.0 7237.2 6148.9 True False 6095.026434139992 8474.532201782098 6208.165364953098 7424.518356766087 2719.6394091721813 7887.4986851450585 9468.289867897107 7921.729835643676 6422.0703249054095 7211.729172105766 0.8451546485848266 1.1751040561202333 0.8608428321137805 1.0295059866478857 0.37711335856752215 1.0937042277811957 1.3129014750747279 1.0984508217923823 0.8905035355106405 1.0 12.816129503756745 -6.940373171523988 24.999999985772888 1.1007788614801666 0.8699717989677621 0.2058864889522959 0.2148346013864849 120.80786990402335 50650.82889769578 0.07742300042817325 0.06828066059960201 1.1471674836827353e-07 6.940373171523988 -0.23080706251240446 GREVS(ph)PSDVR ddPTM_PC-9_Lapatinib_30min_R1 1 GREVSPSDVR 10 1 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 GREVS(0.752)PS(0.248)DVR 63.602 0.025687 8485800.0 71599.0 53725.0 46291.0 38692.0 43221.0 49293.0 42491.0 39227.0 51805.0 34150.0 True False 70577.98513035142 53600.60306335414 42485.13266842745 41537.538752728244 40678.82575575542 47184.8532975953 44690.97606994022 41049.62962520404 45970.17536916555 40052.78199798531 1.7621244170729902 1.3382491899326818 1.0607286322973644 1.0370700031477869 1.0156304687599877 1.178066814434232 1.1158020452159407 1.0248883492604552 1.147739884122853 1.0 15.289614832802808 -4.835652075700639 2.112786039879246 1.0745785299586401 1.9052210199946686 0.9325405765116102 0.05724525043359596 0.13959476576978386 0.7824588379865375 0.015727343386528564 0.215332106996088 1.4599834215546522e-05 4.835652075700639 0.8306424900360285 GRGGS(ph)GGGGGGGGGGYNR ddPTM_PC-9_AZD4547_30min_R2 2 GRGGSGGGGGGGGGGYNR 18 1 H3BPE7;P35637-2;P35637;H3BNZ4 H3BPE7 FUS RNA-binding protein FUS 1 GRGGS(1)GGGGGGGGGGYNR;GRGGS(1)GGGGGGGGGGYNR 101.61 0.0014562999999999998 632430.0 0.0 0.0 1384.85 2678.09 1120.3600000000001 937.26 0.0 1586.98 1261.74 0.0 True False 0.0 0.0 1366.4859841550847 2060.6977265780415 964.8173528212978 878.652984035149 0.0 1341.7487061724876 1328.4330005067372 0.0 0.0 GRLDS(ph)SEMDHSENEDYTMSSPLPGK ddPTM_PC-9_AZD4547_30min_R2 1 GRLDSSEMDHSENEDYTMSSPLPGK 25 1 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 GRLDS(0.344)S(0.344)EMDHS(0.29)ENEDY(0.01)T(0.011)MS(0.001)S(0.001)PLPGK 52.754 0.0065482 7142200.0 17673.0 17005.0 22946.0 33083.0 25959.0 19483.0 14831.0 24462.0 16352.0 22221.0 True False 23292.646378763908 22501.533699100644 22641.72104734993 25456.225477254815 22355.040934956683 18264.72493006935 16150.930268545999 20681.95998083868 17216.333336730368 21443.049553546007 1.0862562398412232 1.0493625751743691 1.055900234283873 1.1871550925481658 1.0425308619995173 0.8517783295916014 0.7532011819594542 0.9645064676641824 0.8028864221825821 1.0 14.38822247484686 -6.688434001956256 4.592797420087234 0.8644271664130301 1.0909578386706666 0.6590146705404465 0.07581535976833859 0.12286643344413309 4.885443501410454 0.025066233029771606 0.02464137749311988 2.0491134220970725e-07 6.688434001956256 0.22653067225763657 GRLDSSEMDHS(ph)ENEDYTMSSPLPGK ddPTM_PC-9_AZD4547_30min_R2 2 GRLDSSEMDHSENEDYTMSSPLPGK 25 1 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 GRLDS(0.045)S(0.045)EMDHS(0.624)ENEDY(0.117)T(0.129)MS(0.031)S(0.008)PLPGK;GRLDSSEMDHS(1)ENEDYTMSSPLPGK 90.978 0.00028708 6654100.0 36329.0 42354.0 52261.0 67381.0 52107.0 50634.0 38075.0 56901.0 42269.0 49938.0 True False 47880.866309857614 56044.102222388035 51567.984993269194 51847.351476072494 44872.842482290835 47467.84797562651 41463.60123895145 48108.2579049016 44503.253046126214 48189.68581994422 0.9935915849038635 1.1629895748187906 1.0701041958635638 1.0759014215156903 0.9311710943697282 0.9850209057802372 0.8604248094473143 0.9983102625871672 0.9235016225755863 1.0 15.556436774786182 -6.255415919268567 23.099736582711774 0.946952098894569 1.0814896068875115 0.5602834693581749 0.0545124526825949 116.9529024284491 448507.65437694907 0.015364951932398167 0.01927325253183562 5.553721284437026e-07 6.255415919268567 0.1345375079929425 GRLGS(ph)VDSFER ddPTM_PC-9_AZD4547_30min_R2 2 GRLGSVDSFER 11 1 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 GRLGS(0.985)VDS(0.015)FER;GRLGS(0.995)VDS(0.005)FER 70.27199999999999 0.015397999999999998 15039100.0 28146.0 25865.0 32764.0 62756.0 46481.0 41343.0 31133.0 41387.0 34325.0 38301.0 True False 37095.84252683125 34225.35543235743 32329.527952382687 48288.573770534786 40027.915470461965 38757.815674375444 33903.776687387406 34991.59012864732 36139.34942412364 36960.093647917085 1.0036728499718457 0.9260083526408008 0.8747144490583465 1.3065057202109152 1.0830036268784662 1.0486395419769092 0.9173076510670064 0.9467397583452634 0.9777937731540435 1.0 15.173680791747532 -7.246881705951233 23.244799268287505 0.9560219431806514 1.0417211831119195 0.11399450174468662 0.10889645590813504 755.0253186918995 1205579.4537096745 0.04536182683541632 0.034934930662999054 5.6639354349954894e-08 7.246881705951233 0.08569923993126816 GRLGS(ph)VDSFER ddPTM_PC-9_Lapatinib_30min_R1 1 GRLGSVDSFER 11 1 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 GRLGS(0.947)VDS(0.053)FER 96.866 0.027160000000000004 11903000.0 40464.0 31486.0 37863.0 28277.0 50166.0 59839.0 49171.0 49055.0 57961.0 42156.0 True False 39886.975939811215 31413.096101494055 34750.05029540664 30356.584909306774 47215.33451015076 57279.82546152202 51716.83378444924 51334.27438408194 51432.82182361167 49442.60843066088 0.8067328404760311 0.6353446369147027 0.7028361042913154 0.6139762013543307 0.9549523378477556 1.1585113989657763 1.0459972769636086 1.0382598332382476 1.0402530015329166 1.0 15.593467236681521 -6.404794623387765 4.292065572992437 1.058426316639708 0.6882437065066974 0.8869391665542279 0.061943379254599945 0.06861452704382799 2.086950350279556 0.0192684755702474 0.021828862013491213 3.937362281673835e-07 6.404794623387765 -0.3701826101330107 GRLPNNS(ph)SRPST(ph)PTINVLESK ddPTM_PC-9_Lapatinib_30min_R1 1 GRLPNNSSRPSTPTINVLESK 21 2 Q15910-5;Q15910-3;Q15910-4;Q15910;Q15910-2 Q15910-5 EZH2 Histone-lysine N-methyltransferase EZH2 2 GRLPNNS(0.839)S(0.258)RPS(0.361)T(0.454)PT(0.088)INVLESK 54.658 0.021047999999999997 4154300.0 25091.0 18484.0 23300.0 24511.0 18767.0 17973.0 15999.0 15794.0 16607.0 10374.0 True False 24733.197738874132 18441.20143365358 21384.36394060097 26313.620706299054 17663.161957341603 17204.33668710934 16827.349936291786 16527.846898831733 14736.544780537257 12167.132077513894 2.0327878074557617 1.5156572079738337 1.7575517224902544 2.162680616817608 1.4517112039890596 1.414000980469729 1.3830169533040948 1.3584012069185052 1.2111765276035673 1.0 13.57070152910143 -6.4569326047791655 5.965307653752506 1.3150446936471205 1.8347520691248194 0.67051562119678 0.19535083211583107 0.15143988918261675 10.398942549054775 0.06155995030335657 0.06920327416750886 3.491945004049432e-07 6.4569326047791655 0.5197073754776989 GRLPNNSS(ph)RPSTPTINVLESK ddPTM_PC-9_Lapatinib_30min_R1 1 GRLPNNSSRPSTPTINVLESK 21 2 Q15910-5;Q15910-3;Q15910-4;Q15910;Q15910-2 Q15910-5 EZH2 Histone-lysine N-methyltransferase EZH2 1 GRLPNNS(0.093)S(0.396)RPS(0.245)T(0.245)PT(0.02)INVLESK 43.696000000000005 0.027756 8898900.0 43505.0 36159.0 45042.0 34675.0 52544.0 51351.0 57896.0 60091.0 59760.0 47982.0 True False 42884.610722160105 36075.27605710233 41338.82062714801 37225.1151724091 49453.465225478656 49154.8374350276 60893.57159269636 62883.04723298074 53029.19949930185 56275.624768003865 0.7620459283917649 0.6410462114960531 0.7345777287691998 0.6614784878154539 0.8787723891000847 0.8734658679964603 1.082059450139025 1.1174118011522032 0.9423120528277492 1.0 15.780222548016042 -6.719730585656342 1.474196672700788 1.0420813787460084 0.6966575340318202 0.828632166624088 0.06601290518215613 0.14500853379418846 0.6564165425682674 0.028475659645372985 0.02671821826644657 1.9066431361929069e-07 6.719730585656342 -0.3454238447141882 GRLPNNSSRPST(ph)PTINVLESK ddPTM_PC-9_AZD4547_30min_R2 1 GRLPNNSSRPSTPTINVLESK 21 2 Q15910-5;Q15910-3;Q15910-4;Q15910;Q15910-2 Q15910-5 EZH2 Histone-lysine N-methyltransferase EZH2 1 GRLPNNS(0.016)S(0.094)RPS(0.102)T(0.447)PT(0.34)INVLESK 56.016999999999996 0.007743000000000001 23485000.0 66558.0 69445.0 87144.0 98247.0 96260.0 108000.0 87894.0 103170.0 91963.0 109820.0 True False 87722.05950759749 91891.73817900875 85988.4136211219 75597.67205101873 82895.96056854785 101246.74292703853 95716.3957267604 87227.44711074827 96823.97643381445 105975.23522660622 0.8277599886428364 0.867105772235534 0.811401016824859 0.7133522458277037 0.782220113890683 0.9553811577822235 0.9031958789437041 0.8230927435473989 0.9136471952789377 1.0 16.69336764309339 -6.7511875204014595 24.99885292499866 0.9070149737508959 0.7998542318500795 0.5241531117831015 0.05596017689752193 199.99035325128975 487669.75076297374 0.01974927814234838 0.0195381687202902 1.7734235837357155e-07 6.7511875204014595 -0.10716074190081637 GRLS(ph)PVPVPR ddPTM_PC-9_AZD4547_30min_R2 6 GRLSPVPVPR 10 1 Q9UKM9-2;Q5QPL9;Q9UKM9;Q5QPM0;Q5QPM1 Q9UKM9-2 RALY RNA-binding protein Raly 1 GRLS(1)PVPVPR;GRLS(1)PVPVPR;GRLS(1)PVPVPR;GRLS(1)PVPVPR;GRLS(1)PVPVPR;GRLS(1)PVPVPR 85.522 0.0055918 4105661200.0 145970.8 136937.2 189071.0 272534.0 243203.0 229373.0 181705.7 221068.0 158890.6 194351.0 True False 192386.4780187447 181199.47194710275 186563.79500320338 209705.49690832658 209438.46143935728 215030.2700500327 197877.15528941623 186907.020237268 167289.2327344109 187546.83064584024 1.0258050075079304 0.9661558732990604 0.9947584523862565 1.1181500438380125 1.1167262102917472 1.1465417427186049 1.0550813074686587 0.9965885298814756 0.8919864556406001 1.0 17.51689135753663 -7.922139785848604 3.5526241948794284 0.9448274474946097 1.061917412761732 0.3847970121422053 0.05863693412186285 0.265616565680331 6.53957055670477 0.0425739921006495 0.01791681918557285 1.1963553998393383e-08 7.922139785848604 0.11708996526712223 GRLS(ph)PVPVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 GRLSPVPVPR 10 1 Q9UKM9-2;Q5QPL9;Q9UKM9;Q5QPM0;Q5QPM1 Q9UKM9-2 RALY RNA-binding protein Raly 1 GRLS(1)PVPVPR;GRLS(1)PVPVPR;GRLS(1)PVPVPR;GRLS(1)PVPVPR;GRLS(1)PVPVPR;GRLS(1)PVPVPR;GRLS(1)PVPVPR 82.85 0.0067703 3430332700.0 364810.9 345691.9 384675.3 481945.5 451969.4 395472.0 466959.0 395242.0 376545.9 325724.2 True False 426566.18002628867 380009.90723382425 393847.41804119997 454943.656123393 363409.24055948533 374732.7521313322 422725.26302960375 384867.3162935147 382052.1714326438 384775.41902865097 1.108610786788659 0.987614822675375 1.0235773871300067 1.1823615377299275 0.9444710409955406 0.9738999260330323 1.0986285560984004 1.000238833512535 0.9929225011231697 1.0 18.55365711143927 -6.318763010061161 24.999998346075824 1.0051625444639896 1.0655508362784685 0.2546337729463912 0.06077184269235774 489.73311060514715 213581.4702140565 0.01938453111187732 0.021979993233998674 4.799953055823764e-07 6.318763010061161 0.06038829181447891 GRLS(ph)PVPVPR ddPTM_PC-9_Lapatinib_30min_R1 3 GRLSPVPVPR 10 1 Q9UKM9-2;Q5QPL9;Q9UKM9;Q5QPM0;Q5QPM1 Q9UKM9-2 RALY RNA-binding protein Raly 1 GRLS(1)PVPVPR;GRLS(1)PVPVPR;GRLS(1)PVPVPR 77.185 0.010434 1969112000.0 97082.1 77132.3 90756.4 74892.2 81334.2 82421.0 69149.9 68675.8 93101.6 61998.6 True False 95697.69145132322 76953.7048983443 83294.75912183528 80400.02222105555 76550.28226518966 78896.04596273512 72730.14346894069 71866.72838133383 82615.51740468871 72714.97540205834 1.3160657886795395 1.0582923871300103 1.1454966279130099 1.1056872642327769 1.0527443878227971 1.085004093400296 1.0002085961907914 0.9883346309885365 1.13615547482328 1.0 16.14996489243435 -1.5228787452803376 0.9221011384616464 1.0531283953065425 141.54689879758232 0.6395649577160221 0.05550163583459162 649.2991640190038 1.2874478901083073 0.01795928086085786 192181.92141242052 0.029999999999999995 1.5228787452803376 140.49377040227577 GRLSPVPVPR ddPTM_PC-9_AZD4547_30min_R2 1 GRLSPVPVPR 10 1 Q9UKM9-2;Q5QPL9;Q9UKM9;Q5QPM0;Q5QPM1 Q9UKM9-2 RALY RNA-binding protein Raly 0 71.03 0.044372 7733100.0 16871.0 17513.0 26345.0 33333.0 27326.0 25826.0 19236.0 26065.0 19896.0 21996.0 False True 22235.627061400195 23173.73476461918 25995.648086482794 25648.591839716297 23532.256581094276 24211.096137349025 20947.96673493025 22037.253164114147 20947.661941510967 21225.92673506134 1.04756919869468 1.0917655117663445 1.224712042539125 1.2083614609556492 1.1086562615060431 1.1406378830732855 0.9869046942637397 1.038223368957203 0.986890334776727 1.0 14.373539923522808 -7.256142654445667 23.905579010006083 1.0061898759128347 1.1408455712924812 0.626920351201881 0.05054340806054703 173.06638949608254 781099.6896179982 0.02153807749572686 0.016156011175118976 5.5444356274889076e-08 7.256142654445667 0.1346556953796465 GRLSPVPVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GRLSPVPVPR 10 1 Q9UKM9-2;Q5QPL9;Q9UKM9;Q5QPM0;Q5QPM1 Q9UKM9-2 RALY RNA-binding protein Raly 0 79.20100000000001 0.042595999999999995 0.0 10661.0 11399.0 11423.0 11403.0 15995.0 9125.4 14511.0 12962.0 9729.9 8054.8 False True 12465.696735651956 12530.61738663346 11695.367641968744 10764.126879024798 12860.89457106823 8646.847959651406 13136.413029457817 12621.76123437424 9872.181380337664 9515.07147823828 1.310100167314769 1.3169230956690101 1.2291413331699055 1.1312712577770125 1.351634047151628 0.9087528117289955 1.3805900522662211 1.3265019882657956 1.0375309741935332 1.0 13.215998778882096 -14.522878744236634 0.11218766291076586 0.2820940690759941 1.3470202778342903 0.23067152434159088 0.13984112077305477 270.0349070322273 1.9959092236328742 44.420779952260716 1.6521423139597693 3.0000000072096517e-15 14.522878744236634 1.0649262087582962 GRLSPVPVPR ddPTM_PC-9_Lapatinib_30min_R1 2 GRLSPVPVPR 10 1 Q9UKM9-2;Q5QPL9;Q9UKM9;Q5QPM0;Q5QPM1 Q9UKM9-2 RALY RNA-binding protein Raly 0 ; 86.344 0.014681 4166100.0 63087.0 49838.0 49101.0 49888.0 55624.0 54726.0 44216.0 42763.0 55633.0 42464.0 False True 62187.367811261116 49722.60317303759 45064.10531534114 53556.92994148941 52352.30568099163 52385.49655253685 46505.288129450426 44749.92509400668 49367.02569853848 49803.84582027665 1.2486458984647881 0.9983687475153579 0.9048318372432633 1.0753573154723077 1.0511699411710376 1.0518363730699916 0.933769016498656 0.898523484621897 0.9912291889402579 1.0 15.603969530108186 -7.258489310234023 24.438931349216812 0.9474240435738169 1.0463799209352418 0.24250931939207454 0.08450190106330212 295.5523224539402 2448427.9553796635 0.03392555669645177 0.025089847243796565 5.5145577579998125e-08 7.258489310234023 0.09895587736142486 GRLT(ph)PSPDIIVLSDNEASSPR ddPTM_PC-9_AZD4547_30min_R2 1 GRLTPSPDIIVLSDNEASSPR 21 1 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 GRLT(0.996)PS(0.004)PDIIVLSDNEASSPR 121.82 0.00040098 0.0 1591.6 3055.5 4293.7 6188.0 5004.7 3392.8 2557.6 5187.4 3610.8 3805.1 True False 2097.695692663421 4043.1306214408705 4236.762732546261 4761.452203646972 4309.8837924102545 3180.6476796560755 2785.2214452722815 4385.806524593355 3801.6595164056985 3671.884607182301 0.5712858428503648 1.1011050329665597 1.1538387465278848 1.2967325264888359 1.1737525149837253 0.8662166761544322 0.758526408979279 1.1944292900748037 1.0353428615293505 1.0 11.842305005924246 -4.759133294097551 24.954081083496458 1.0682290338227192 0.5712851828729263 0.4873056939165997 0.15170591679337278 57.757956817854975 624853.0330631852 0.041667767107222455 0.270445152866919 1.7412723583118812e-05 4.759133294097551 -0.4969438509497929 GRLT(ph)PSPDIIVLSDNEASSPR ddPTM_PC-9_Lapatinib_30min_R1 1 GRLTPSPDIIVLSDNEASSPR 21 1 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 GRLT(0.643)PS(0.354)PDIIVLS(0.002)DNEAS(0.001)SPR 118.15 0.00078967 0.0 6882.0 5668.0 6916.5 5451.4 7189.3 4699.3 4543.9 5549.4 5829.3 2993.0 True False 6783.861417995771 5654.876094240879 6347.852068462087 5852.314141337302 6766.439508707629 4498.32189360334 4779.160908526548 5807.2453830807135 5172.742848749669 3510.3360620781864 1.932539021343613 1.610921573956963 1.8083317255681888 1.667166344715332 1.9275759896053277 1.2814504976313428 1.3614539531286909 1.6543274718953014 1.4735748251087122 1.0 11.777393438236095 -6.765113902071926 24.999975445858034 1.3955125810770543 1.7736679877092991 0.5829737579887448 0.1821092196608342 77.85881546888994 529716.0175653431 0.06140641243277684 0.05624685132077724 1.7174578917552115e-07 6.765113902071926 0.3781554066322448 GRLTPS(ph)PDIIVLSDNEASSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GRLTPSPDIIVLSDNEASSPR 21 1 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 GRLT(0.295)PS(0.617)PDIIVLS(0.017)DNEAS(0.028)S(0.044)PR 79.51100000000001 0.0186 0.0 2908.6 2789.0 3864.9 3259.3 2978.5 2539.1 3745.3 2691.2 2321.6 2671.9 True False 3400.968532531403 3065.8734881411265 3957.053873714874 3076.69198779317 2394.8843063411523 2405.945126169911 3390.5180703761557 2620.5588515621007 2355.549007964309 3156.2943192512394 1.0775194543131856 0.9713522181506942 1.2537024350294421 0.9747798134753944 0.7587645713943703 0.7622689403504892 1.0742084632907367 0.8302644134225639 0.7463020775968418 1.0 11.624016025224599 -5.99962015907994 24.999978722615435 0.8598050638740102 1.092296429647132 0.45072274543425017 0.11832127961629182 12.535090784893299 824858.8898366103 0.033597297301815245 0.04931161084183701 1.0008749986283802e-06 5.99962015907994 0.2324913657731218 GRLTPSPDIIVLS(ph)DNEASSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GRLTPSPDIIVLSDNEASSPR 21 1 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 GRLT(0.001)PS(0.003)PDIIVLS(0.803)DNEAS(0.161)S(0.033)PR 79.875 0.017631 0.0 3082.8 2448.2 3750.0 3091.9 4048.2 3317.6 4377.0 2457.3 3745.4 2231.1 True False 3604.657151924573 2691.241116409863 3839.414221954194 2918.670867075049 3254.984270246853 3143.619215698983 3962.3788732642056 2392.7984787245646 3800.169389399346 2635.580768622117 1.3676898825639443 1.021118816941757 1.456762117732951 1.1074108985098308 1.235015943733935 1.192761479035404 1.503417736401127 0.9078828117172524 1.4418717250642548 1.0 11.36390518948047 -10.92884731832292 3.704276242078102 0.9984971799402218 1.2390048247008203 0.1345884065441677 0.18751924421574023 19549491.159751143 28842781.26264339 191757.65434594778 0.041069917245874756 1.1780200484663735e-11 10.92884731832292 0.2405076447605985 GRNDS(ph)GEENVPLDLTR ddPTM_PC-9_AZD4547_30min_R2 2 GRNDSGEENVPLDLTR 16 1 Q6R327-3;Q6R327;Q6R327-4 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 GRNDS(1)GEENVPLDLTR;GRNDS(1)GEENVPLDLTR 105.67 0.00052151 12864400.0 24132.0 29974.0 34770.0 38911.0 30528.0 38211.0 24898.0 37518.0 31735.0 32126.0 True False 31805.474023217925 39662.509326482934 34308.92708168557 29940.670118957212 26289.714151637487 35821.660129491334 27113.873766182867 31720.455177872052 33412.44731171344 31001.27851839337 1.025940720617294 1.2793830197341949 1.1066939404234486 0.9657882368042696 0.8480203207115969 1.1554897682119136 0.874605018309033 1.0231982903238004 1.0777764307975073 1.0 14.920040094213823 -5.62740160989465 4.71385753748635 0.9895396338185023 1.1614901013702181 0.3046247932741347 0.1014920091874549 0.2240197409614675 8.30688762340924 0.026887944439558796 0.04796507950387831 2.358296411246676e-06 5.62740160989465 0.17195046755171584 GRNDS(ph)GEENVPLDLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GRNDSGEENVPLDLTR 16 1 Q6R327-3;Q6R327;Q6R327-4 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 GRNDS(1)GEENVPLDLTR;GRNDS(1)GEENVPLDLTR;GRNDS(1)GEENVPLDLTR;GRNDS(1)GEENVPLDLTR 95.62200000000001 0.00115 23187400.0 73717.0 96847.0 88245.0 87036.0 96319.0 68457.0 92127.0 78391.0 68217.0 57441.0 True False 86195.83212288303 106461.33012047483 90349.09547102624 82159.65509451917 77445.9833817269 64866.99440833901 83400.06361827992 76333.31931213016 69214.5445711152 67854.59859729407 1.270301997281587 1.5689626395449687 1.3315102784298134 1.2108192634389199 1.1413520230420362 0.9559704979365363 1.2290996534110479 1.1249542535083865 1.020042060552037 1.0 16.050158971887697 -5.876671211966748 1.8916649843671351 1.0853695517918105 1.4247048908215814 0.6643143893083193 0.10004748719590305 0.196634792579914 1.4340085760963943 0.030986248947129785 0.055876892114861576 1.3283997586854466e-06 5.876671211966748 0.33933533902977087 GRNDS(ph)GEENVPLDLTR ddPTM_PC-9_Lapatinib_30min_R1 5 GRNDSGEENVPLDLTR 16 1 Q6R327-3;Q6R327;Q6R327-4 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 GRNDS(1)GEENVPLDLTR;GRNDS(1)GEENVPLDLTR;GRNDS(1)GEENVPLDLTR;GRNDS(1)GEENVPLDLTR;GRNDS(1)GEENVPLDLTR 152.66 6.2601e-05 28241400.0 50529.9 70592.5 79052.2 55612.3 78316.1 76060.7 72417.9 71580.5 80181.3 68170.7 True False 49809.33435995122 70429.04740344017 72552.83326631658 59702.214059194375 73709.70097337682 72807.76116715172 76167.34451849395 74906.39134746268 71150.4376474795 79953.91466325191 0.6229755549773522 0.8808705327321575 0.9074331578621629 0.7467078292619793 0.9219023394142197 0.9106215933741556 0.9526405910116327 0.936869591225792 0.8898931083881171 1.0 16.28688105149144 -4.329168107632999 1.7479615581537058 0.9051551081968423 1.065529816819252e-09 0.6484716771840514 0.0622383208171684 2.6560381393815766 2.772312555972131 0.017439804965615258 5.9469359298758935 4.6863194798007086e-05 4.329168107632999 -0.9051551071313125 GRNDS(ph)GEENVPLDLTREPSDNLR ddPTM_PC-9_AZD4547_30min_R2 1 GRNDSGEENVPLDLTREPSDNLR 23 2 Q6R327-3;Q6R327;Q6R327-4 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 GRNDS(0.999)GEENVPLDLT(0.001)REPSDNLR 50.88399999999999 0.0090416 8338800.0 2501.4 4178.3 8682.7 9807.7 5537.4 5244.2 4833.3 7308.9 3889.9 7336.9 True False 3296.7931676478265 5528.85376389016 8567.561724824602 7546.686292454493 4768.6275924815745 4916.27934498125 5263.45433665723 6179.477446813504 4095.512172611756 7080.037364178556 0.46564629507860356 0.7809074273906225 1.210101202032093 1.0659105177377943 0.6735314161770448 0.6943860734203412 0.7434218304111886 0.8728029428317096 0.5784591184974527 1.0 12.789541258667093 -6.287265183166025 24.849847530845878 0.7499207558127121 0.8970504183671821 0.0693387783211743 0.21026499822351974 1821.3548792742881 1752520.2365222094 0.0686585285112163 0.07787670253433578 5.161011381737e-07 6.287265183166025 0.14712966255447002 GRNDS(ph)GEENVPLDLTREPSDNLR ddPTM_PC-9_Lapatinib_30min_R1 1 GRNDSGEENVPLDLTREPSDNLR 23 2 Q6R327-3;Q6R327;Q6R327-4 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 GRNDS(1)GEENVPLDLTREPSDNLR 42.528999999999996 0.026749000000000002 6843800.0 5796.3 6229.7 9273.0 6818.3 9956.8 8925.0 8544.7 6038.9 8823.0 6239.4 True False 5713.643699088766 6215.275512401625 8510.60973481514 7319.740527182033 9371.16059982197 8543.29855519116 8987.102756461807 6319.4893400883175 7829.260829691105 7317.87197652209 0.7807794010908956 0.8493282654222535 1.162989700027509 1.0002553407146144 1.2805854802991141 1.167456684484315 1.228103304525565 0.8635692671808305 1.0698821808866978 1.0 12.837208461140904 -5.170932399420779 4.707547428222597 1.101911538886029 0.798906657010869 0.48483526412993194 0.11648493813913392 0.18667728338806083 6.9745381541229206 0.031037059709767622 0.08882848028270701 6.746330302625378e-06 5.170932399420779 -0.30300488187515995 GRNS(ph)ATSADEQPHIGNYR ddPTM_PC-9_AZD4547_30min_R2 2 GRNSATSADEQPHIGNYR 18 1 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;F5H4J8;F5H6N2;F5H4F6;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 GRNS(0.983)AT(0.012)S(0.005)ADEQPHIGNYR;GRNS(0.761)AT(0.234)S(0.004)ADEQPHIGNYR 94.271 0.00045686 37510000.0 20730.0 21897.9 30111.8 44925.0 32717.0 37658.0 22290.3 44461.0 27228.7 38416.0 True False 27321.7087892138 28975.96793822615 29712.49785729939 34568.23533433101 28174.8092865279 35303.239306911215 24274.093517967154 37590.57406214001 28667.953493507222 37071.067532920366 0.7370089562419856 0.7816329516945932 0.8015010042781661 0.9324855644805277 0.7600215251828859 0.9523124543300713 0.6547988804587549 1.0140138000816488 0.7733241959662777 1.0 15.178006040492182 -14.522878745235532 0.09420821678214532 1.5283869691647152 0.7016052711809473 0.22679234862530773 0.10317757202954457 300.06675901550267 1.940130059069887 31.873992692146746 1.9698998948134 3.0000000003095035e-15 14.522878745235532 -0.8267816979837679 GRNS(ph)ATSADEQPHIGNYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GRNSATSADEQPHIGNYR 18 1 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;F5H4J8;F5H6N2;F5H4F6;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 GRNS(0.984)AT(0.012)S(0.004)ADEQPHIGNYR 103.2 0.00019674 11651000.0 8963.3 12432.0 9907.0 9949.9 10244.0 11947.0 11506.0 9713.5 7105.6 7317.7 True False 10480.609656755383 13666.166799774295 10143.220452506723 9392.439361011038 8236.7617371693 11320.478288508488 10416.068383773803 9458.530917303973 7209.505957525499 8644.341083118668 1.212424354381703 1.5809379417550555 1.173394288237328 1.0865419666691905 0.952850154565821 1.3095825557619407 1.2049580510092435 1.0941876108724258 0.8340145174980167 1.0 13.077540282960344 -3.1228151767098793 0.23079052843110062 0.9657741659570074 2.246883681128546 0.34731036525597014 0.15887649507636026 28.925526304649452 0.7152611769223777 0.253634515774556 12.040201924571047 0.0007536762385101765 3.1228151767098793 1.2811095151715386 GRNS(ph)ATSADEQPHIGNYR ddPTM_PC-9_Lapatinib_30min_R1 2 GRNSATSADEQPHIGNYR 18 1 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;F5H4J8;F5H6N2;F5H4F6;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 GRNS(0.685)AT(0.257)S(0.059)ADEQPHIGNYR;GRNS(0.994)AT(0.004)S(0.002)ADEQPHIGNYR 166.34 6.1015e-08 30003000.0 18846.4 19410.7 19484.5 15326.599999999999 16104.699999999999 18917.2 14062.7 16002.2 20066.4 15930.1 True False 18577.646879993525 19365.755716739845 17882.55962234505 16453.7692920388 15157.453209058427 18108.155454147032 14790.797796680436 16745.720630903197 17806.31072344028 18683.59655947602 0.9943292674327867 1.0365111264896074 0.9571261917061307 0.8806532104063076 0.8112706330821948 0.9692007315884192 0.7916461774153853 0.8962792884975905 0.9530451306180237 1.0 14.189484577588285 -5.549502826310184 3.5383462862836947 0.8909323263195301 1.013891086141285 0.3455600743693945 0.06265623972722517 0.2215324798996151 5.853098385312769 0.016748546489853446 0.03336227093777158 2.8216112204939725e-06 5.549502826310184 0.12295875982175497 GRPS(ph)LTGENLEAK ddPTM_PC-9_AZD4547_30min_R2 2 GRPSLTGENLEAK 13 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 GRPS(0.876)LT(0.124)GENLEAK;GRPS(0.583)LT(0.417)GENLEAK 71.263 0.01241 24843000.0 82842.0 63287.0 58086.0 88469.0 91575.0 71397.0 73028.0 77526.0 71263.0 91598.0 True False 109184.0327793561 83743.28510526205 57315.74168728182 68073.83888242474 78861.39194956113 66932.53430334979 79527.35052601817 65546.13807025173 75029.81669370197 88391.18190026112 1.2352367106320314 0.9474167366576944 0.6484328012714637 0.7701428741979933 0.8921861915880567 0.7572309009158307 0.8997204112029555 0.7415461210170571 0.8488382560419223 1.0 16.431614829897818 -4.850157636408933 3.4336329762598212 0.8111064485924361 1.2586786841309077 0.6377987083650429 0.09443756911550105 0.15202532614802172 2.980237769697762 0.02271352619697874 0.1601333935800963 1.4120249271494478e-05 4.850157636408933 0.4475722355384716 GRPS(ph)LYVQR ddPTM_PC-9_AZD4547_30min_R2 1 GRPSLYVQR 9 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 GRPS(1)LYVQR 92.611 0.0032531999999999995 6959900.0 7924.6 8383.9 12151.0 10929.0 13906.0 9388.2 11539.0 16132.0 12954.0 11580.0 True False 10444.457958080253 11093.831718899723 11989.869800677647 8409.4879013668 11975.391935032465 8801.154369885387 12565.948645995022 13639.170076481472 13638.721993884848 11174.587724677684 0.9346615924822864 0.9927732451730974 1.072958582104959 0.7525546452864202 1.07166297585962 0.7876043919230359 1.1245111636865754 1.2205524188029833 1.2205123204469934 1.0 13.447933985138365 -7.438589946031085 7.6339413977981625 1.166867043418616 0.9424568196219274 0.43658827297856584 0.11401629570161192 0.2459789437464052 19.79837760885068 0.04564324763713538 0.03058304059005917 3.64258801201732e-08 7.438589946031085 -0.2244102237966885 GRPS(ph)LYVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GRPSLYVQR 9 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 GRPS(1)LYVQR 64.22399999999999 0.02567 4764600.0 13030.0 13854.0 13277.0 12094.0 19070.0 13259.0 9624.4 18933.0 11669.0 9263.8 True False 15235.721645769154 15229.333562103688 13593.574033302895 11416.412389277033 15333.370395140433 12563.67469886449 8712.707157378114 18436.028811171687 11839.637049420882 10943.253607799556 1.3922478809145242 1.3916641346271392 1.2421876089588553 1.0432374866228307 1.401171072578627 1.1480748915395707 0.796171547296348 1.6846935538468948 1.081911968208655 1.0 13.417754118225828 -5.343064927246697 3.9376540411392984 1.1848743061290008 1.393896672225701 0.13052806785798665 0.22685219927557315 0.48240367505516124 13.92904854245662 0.0593883339318768 0.13771001624013043 4.5387375721947005e-06 5.343064927246697 0.2090223660967001 GRPS(ph)LYVQR ddPTM_PC-9_Lapatinib_30min_R1 2 GRPSLYVQR 9 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 GRPS(0.999)LY(0.001)VQR;GRPS(1)LYVQR 87.713 0.0050381 9695500.0 34757.0 21077.4 26802.0 34924.0 27526.0 22654.0 25182.0 24521.0 32311.0 26270.0 True False 34261.358806346834 21028.59657529161 24598.443018711903 37492.427463048734 25906.974798198167 21685.141229053283 26485.800743527703 25660.335178311558 28671.794930086042 30810.7344974253 1.111994224260051 0.6825087722932689 0.798372496467667 1.2168625018070176 0.8408424927475547 0.7038177305012122 0.859628995399022 0.832837502801365 0.930578105253609 1.0 14.911145454758987 -4.7236874408708545 23.86351748430479 0.8702721372327926 1.1119981287051999 0.19421797238432725 0.14529400313718335 6921.117211862777 4374441.861342548 0.03716842889166044 9.376684115211061 1.889350614194939e-05 4.7236874408708545 0.24172599147240725 GRPYDYNGPR ddPTM_PC-9_AZD4547_30min_R2 3 GRPYDYNGPR 10 1 A0A499FI48;P13667 A0A499FI48 PDIA4 Protein disulfide-isomerase A4 0 ;; 110.54 0.0022356999999999998 9699900.0 33198.7 31628.4 40691.0 62523.0 43382.0 37915.0 32353.8 45567.0 34696.2 40228.0 False True 43755.19602414243 41851.66177292761 40151.4107529729 48109.28832072069 37359.158127828145 35544.169056283885 35233.22552238442 38525.66717549167 36530.17029830381 38819.629964450214 1.1271409867691178 1.0781056339602937 1.0343068903475456 1.239303114552551 0.9623780072618022 0.9156235927244568 0.907613636571237 0.9924274706062951 0.941023145551799 1.0 15.24449874564335 -6.408192151803645 8.775465464784752 0.9471566593452707 1.1104334073175877 0.6799090921315637 0.05583525688717564 0.19239952997326593 13.53977586870029 0.017075784318595716 0.019354459765663697 3.906680080983893e-07 6.408192151803645 0.16327674797231695 GRPYDYNGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GRPYDYNGPR 10 1 A0A499FI48;P13667 A0A499FI48 PDIA4 Protein disulfide-isomerase A4 0 ;;; 123.51 0.00058182 11234600.0 45344.2 45891.0 54748.7 51809.299999999996 57951.0 63133.3 53346.0 47183.200000000004 50049.1 45784.299999999996 False True 53020.07747122686 50446.75519694672 56054.116643600995 48906.5928890169 46595.91755473432 59822.47860817719 48292.680688405824 45944.69099473277 50780.97340390528 54084.6311616806 0.9803168909986395 0.932737343555902 1.0364148823726433 0.9042604495686682 0.8615371234656382 1.1060901650478834 0.8929094948256129 0.8494962433484239 0.9389168847634485 1.0 15.722931071626764 GRPYDYNGPR ddPTM_PC-9_Lapatinib_30min_R1 3 GRPYDYNGPR 10 1 A0A499FI48;P13667 A0A499FI48 PDIA4 Protein disulfide-isomerase A4 0 ;; 82.494 0.019233 13322500.0 107336.0 36038.6 32559.1 34541.1 36065.8 35454.1 36846.8 40038.5 41599.7 29083.1 False True 105805.3689569881 35955.15483590498 29882.216479760576 37081.36771973177 33944.48055209096 33937.810790543765 38754.54701122292 41898.8348777304 36914.30372173875 34110.07508420516 3.101880271321414 1.0540919287672337 0.8760524978614804 1.0871089444450528 0.9951452897214267 0.9949497533137603 1.1361612929772884 1.2283419128893054 1.08221115405378 1.0 15.057910310211444 -4.7614417720011275 13.00163297632702 1.0523969666539121 3.103501809568133 0.9791913003285309 0.08971490941115799 0.007529140361623154 109.34175675824214 0.0243171223471151 0.13579509677268548 1.732041238477444e-05 4.7614417720011275 2.0511048429142207 GRRS(ph)PILLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GRRSPILLPK 10 2 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 GRRS(1)PILLPK 84.734 0.034736 50017000.0 86944.0 50236.0 71308.0 102290.0 110770.0 110320.0 101570.0 123010.0 115840.0 79779.0 True False 101661.90197772473 55223.09808184214 73008.25315709581 96559.02292865435 89065.41366909843 104534.62499273922 91948.55429688051 119781.11783986869 117533.94085225077 94242.3011697836 1.0787289859844809 0.5859693300819783 0.7746866561075022 1.0245826102516005 0.9450683245588551 1.1092112957260385 0.9756611750304064 1.2709910130916184 1.2471463386755144 1.0 16.524087146282582 -6.452066725787286 0.9275249566646618 1.157212812773022 0.7981244160590925 0.41117199361146817 0.1493932586844226 0.5167261052027686 0.9657569523991337 0.07829829405274745 0.10090913730930956 3.5312891026129045e-07 6.452066725787286 -0.35908839671392945 GRRVGVEVT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 GRRVGVEVTPR 11 2 Q92925-3 Q92925-3 SMARCD2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 1 GRRVGVEVT(1)PR 58.223 0.034459 5518000.0 43730.0 41690.0 22522.0 35695.0 27992.0 21508.0 30785.0 29819.0 21976.0 27166.0 True False 43106.402180900135 41593.46936642594 20670.328097434125 38320.12937502936 26345.565594389434 20588.152977596805 32378.89666783813 31204.499599611463 19500.8314624608 31861.606903580338 1.35292618201426 1.3054416712972507 0.6487534718505164 1.2027054847231597 0.8268749807288892 0.6461743451892027 1.0162355202555606 0.9793762032794701 0.6120479585814443 1.0 14.959531408916309 -5.195207617303253 8.489988174438809 0.8740438574322632 1.332826751355355 0.5091665649764094 0.18160278481175032 0.2946535871021352 35.13314297331823 0.04492859092153546 0.11966285858547157 6.379584330995817e-06 5.195207617303253 0.4587828939230919 GRS(ph)FAGNLNTYK ddPTM_PC-9_AZD4547_30min_R2 2 GRSFAGNLNTYK 12 1 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 1 GRS(1)FAGNLNTYK;GRS(1)FAGNLNTYK 127.66 0.00010735 112491000.0 184195.0 177180.0 243718.0 265347.0 218126.0 209764.0 196915.0 258619.0 197395.0 209204.0 True False 242765.17850599272 234449.97005625695 240486.14007748745 204175.3487202831 187842.97002882877 196647.42391988199 214440.05352509863 218655.37602340462 207828.89671012064 201879.831636742 1.2025231868769284 1.1613342856265154 1.1912341026230533 1.0113707103128142 0.9304692227345878 0.9740815728127064 1.062216328330198 1.083096683064647 1.0294683477053976 1.0 17.62313726301094 -5.762780280763732 24.998961721085784 1.0134155001028118 1.1826609302659896 0.7849605024992605 0.04126611153334598 17.850380595904827 332802.09573126276 0.013259866646426956 0.02094334904137732 1.7267112526667406e-06 5.762780280763732 0.16924543016317783 GRS(ph)FAGNLNTYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GRSFAGNLNTYK 12 1 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 1 GRS(1)FAGNLNTYK;GRS(1)FAGNLNTYK;GRS(0.999)FAGNLNT(0.001)YK;GRS(1)FAGNLNTYK 91.789 0.0029318 83206900.0 230023.0 200653.0 216860.0 233503.0 297955.0 226393.0 265548.0 245811.0 224691.0 170401.0 True False 268961.3507386619 220572.5037705207 222030.76484613 220420.58393694015 239572.85663786373 214520.55253790127 240393.3710389681 239358.72170828338 227976.68080139102 201293.35240642665 1.3361660855824409 1.0957763936742828 1.1030208508715824 1.0950216750918538 1.1901677515616504 1.065711062851037 1.1942439636734525 1.1891039562250414 1.1325594118035687 1.0 17.618940003334714 -4.756395407405117 24.99991008078388 1.1260651337783516 1.336166409492303 0.548328380560229 0.05892431797581988 121.41041434491574 601689.6690017001 0.014136832009918469 0.11498867779782844 1.7522843919157144e-05 4.756395407405117 0.21010127571395132 GRS(ph)FAGNLNTYK ddPTM_PC-9_Lapatinib_30min_R1 2 GRSFAGNLNTYK 12 1 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 1 GRS(1)FAGNLNTYK;GRS(1)FAGNLNTYK 97.073 0.0019274000000000001 87136000.0 177894.0 134524.0 169799.0 134563.0 133446.0 136959.0 134289.0 117569.0 165250.0 112034.0 True False 175357.19893823582 134212.51794313025 155838.78166309444 144459.2119090092 125596.9686449305 131101.5828370225 141241.82733887655 123031.68494673625 146637.80484035518 131398.9276240786 1.3345405636788616 1.021412582050145 1.1859973629993101 1.0993941466729087 0.955844700683197 0.9977370836091843 1.0749085239337544 0.9363218343662564 1.1159741368656655 1.0 17.003593975989467 -1.5228787453368897 0.7039290558738514 1.0221889020392139 36.03931449877907 0.5482086049473651 0.07657067767037164 227.75236751475103 1.1904382106580795 0.02939487661372123 12560.39932556674 0.029999999996093516 1.5228787453368897 35.01712559673986 GRS(ph)IDQDYER ddPTM_PC-9_AZD4547_30min_R2 2 GRSIDQDYER 10 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 GRS(1)IDQDYER;GRS(1)IDQDYER 74.392 0.012239 188746000.0 19708.4 20158.1 26066.6 30899.5 31934.4 21064.1 20176.7 28932.0 23619.5 18161.6 True False 25975.261239813877 26673.811611869463 25720.93985238612 23776.097667516107 27500.859787868594 19746.95849712436 21972.387212552894 24461.224191220066 24867.97854983507 17525.7679119608 1.4821182940626845 1.5219767684853 1.467607010522624 1.3566365700466483 1.569167178637582 1.126738559834954 1.2537189424697 1.3957290952441537 1.4189380274095398 1.0 14.097190038536057 -6.754187518734256 24.99997882737073 1.2646763645316206 1.4743743223405366 0.4759879962944823 0.12465620290983524 173.24885976804825 597255.2875123593 0.04165688935360166 0.040834775053847215 1.7612154284171943e-07 6.754187518734256 0.20969795780891598 GRS(ph)IDQDYER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GRSIDQDYER 10 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 GRS(1)IDQDYER;GRS(1)IDQDYER;GRS(1)IDQDYER 73.84100000000001 0.012694 46958000.0 21234.5 15844.400000000001 28215.9 30957.7 31406.1 28433.2 25644.0 25995.100000000002 27227.8 23658.4 True False 24829.081449507707 17417.327320008353 28888.674065396648 29223.24043521757 25252.30015557525 26942.112938212078 23214.81467351777 25312.756169085165 27625.955065063154 27947.480640208647 0.8884193093879656 0.6232163658769895 1.0336772189702812 1.0456484722695705 0.9035626674428827 0.9640265355242746 0.830658583232655 0.9057258682797745 0.9884953645988788 1.0 14.770430614972188 -5.270733061258155 24.949383199548144 0.9523216523097929 0.7558178313644539 0.47169685219257973 0.08576958923180523 498.10263047912593 1337184.7253142085 0.02243812945156835 0.04777449922429337 5.361260857139601e-06 5.270733061258155 -0.19650382094533902 GRS(ph)IDQDYER ddPTM_PC-9_Lapatinib_30min_R1 2 GRSIDQDYER 10 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 GRS(1)IDQDYER;GRS(1)IDQDYER 78.342 0.0096856 103107000.0 29766.8 29112.6 27588.1 28724.5 30366.6 31026.0 29913.2 27584.0 30540.1 20837.0 True False 29342.319973437414 29045.191563372813 25319.912911145642 30836.995552123 28580.496291032636 29699.090305138496 31461.95912958831 28865.653340342833 27100.35233648976 24438.647686442753 1.2006523580973327 1.1884942217766625 1.0360603105380404 1.261812680790423 1.1694794514709403 1.2152509699468335 1.28738543692177 1.1811477341422596 1.1089137453183866 1.0 14.576876835326368 -8.543196255238994 2.5162634825999923 1.0009965564945333 1.1926314479025162 0.4792685028255871 0.06289919426416529 0.2618776697638817 3.9833218451166283 0.06214651869970736 0.016855040894123405 2.8628839563572697e-09 8.543196255238994 0.19163489140798284 GRS(ph)PDELPSAGGDGGK ddPTM_PC-9_AZD4547_30min_R2 2 GRSPDELPSAGGDGGK 16 1 B4E2I7;A0A2R8Y5N1;A0A140T8Z0;A0A0G2JH68;O60610-2;O60610-3;O60610 B4E2I7 DIAPH1 Protein diaphanous homolog 1 1 GRS(0.999)PDELPS(0.001)AGGDGGK;GRS(1)PDELPSAGGDGGK 85.57600000000001 0.0050898 25783600.0 84817.0 90933.0 125074.0 161379.0 127166.0 125663.0 115651.0 117851.0 114336.0 112224.0 True False 111787.04169680378 120325.31395826631 123415.43703810012 124175.56483069572 109511.19594493996 117805.27274481853 125943.71495432648 99639.83589656676 120379.56753842968 108295.07191832733 1.0322449555332487 1.1110876222420518 1.1396219130929253 1.1466409563340514 1.0112297263861627 1.087817484748184 1.162968108551691 0.9200772863580711 1.1115886014574705 1.0 16.72460806751458 -7.749971904636911 24.99999964533987 1.0118746812772021 1.098893451755732 0.29562038374097177 0.0624124884075282 263.8019916870388 575112.346752336 0.02888774941489536 0.016495762649263973 1.7783944541480857e-08 7.749971904636911 0.0870187704785299 GRS(ph)PDELPSAGGDGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GRSPDELPSAGGDGGK 16 1 B4E2I7;A0A2R8Y5N1;A0A140T8Z0;A0A0G2JH68;O60610-2;O60610-3;O60610 B4E2I7 DIAPH1 Protein diaphanous homolog 1 1 GRS(1)PDELPSAGGDGGK 85.493 0.0022248000000000003 14413000.0 78488.0 68951.0 79119.0 92498.0 94713.0 80779.0 96221.0 74221.0 81567.0 66018.0 True False 91774.46819133789 75795.99959871589 81005.49702047839 87315.63694256225 76154.66755295945 76542.80703669773 87106.25030028675 72272.77739364999 82759.76306539653 77986.54080179942 1.1767988071759727 0.9719112916079875 1.0387112466797517 1.1196244383306149 0.9765103923060824 0.981487398334914 1.1169395309078372 0.9267339806407006 1.0612057185063268 1.0 16.25093753949902 -4.749405462257669 24.995966487507832 1.023105594909109 1.1767991559902724 0.37496152877542044 0.060134232739932014 604.5211484813476 1255590.0929326364 0.01442905294780825 0.23688967956747195 1.780715494946158e-05 4.749405462257669 0.1536935610811634 GRS(ph)PDELPSAGGDGGK ddPTM_PC-9_Lapatinib_30min_R1 3 GRSPDELPSAGGDGGK 16 1 B4E2I7;A0A2R8Y5N1;A0A140T8Z0;A0A0G2JH68;O60610-2;O60610-3;O60610 B4E2I7 DIAPH1 Protein diaphanous homolog 1 1 GRS(1)PDELPSAGGDGGK;GRS(1)PDELPSAGGDGGK;GRS(0.992)PDELPS(0.008)AGGDGGK 122.16 0.00030379 48253600.0 181200.8 165485.0 174043.0 147652.6 157473.4 168215.7 154600.0 125746.5 157369.2 125849.7 True False 178616.84336384296 165101.82964986798 159733.85636540828 158511.4647586347 148211.12421661636 161021.50664094905 162604.43153639048 131589.14145016737 139644.62352485824 147602.6529608158 1.210119464527921 1.118555976725552 1.0821882477126816 1.0739066106129873 1.0041223598871363 1.0909120087678612 1.1016362394215042 0.8915093245993381 0.9460847804810787 1.0 17.171359126587262 -1.5228787452803376 0.24348609034001661 0.9577227426064036 2.41991598769014 0.6075860358007097 0.05488754702658229 37.152221321080575 0.49958031314395707 0.07961791329032838 22.05492780761133 0.029999999999999995 1.5228787452803376 1.4621932450837365 GRS(ph)PQPPAEEDEDDFDDTLVAIDTYNCDLHFK ddPTM_PC-9_AZD4547_30min_R2 2 GRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFK 32 1 M0R3F1;A0A0A0MRA5;B7Z4B8;Q9BUJ2-3;Q9BUJ2-4;Q9BUJ2-2;Q9BUJ2;M0R0K8;M0QYI8;M0QYZ0 M0R3F1 HNRNPUL1 Heterogeneous nuclear ribonucleoprotein U-like protein 1 1 GRS(1)PQPPAEEDEDDFDDTLVAIDTYNCDLHFK;GRS(1)PQPPAEEDEDDFDDTLVAIDTYNCDLHFK 120.27 4.2383e-18 10735600.0 21331.5 21377.6 35191.8 35764.0 32735.4 34989.5 30239.5 38147.5 30556.7 33513.8 True False 28114.4732772366 28287.491138247187 34725.13373808638 27519.16234829189 28190.654764135026 32801.601033755665 32930.75691832625 32252.680417342985 32171.864779260562 32340.492062806803 0.8693273195298615 0.8746772029105652 1.0737354790597646 0.8509197168320242 0.8716829264498329 1.0142579454280833 1.0182515731168569 0.9972847770747185 0.9947858776168662 1.0 14.9810540092321 -6.773829285764815 24.94791545545499 1.0055798260909845 0.912242240628032 0.3989628781344141 0.05932178424088372 253.59814782577007 510634.03625783295 0.021581010347504342 0.019165803224843642 1.6833356234267266e-07 6.773829285764815 -0.09333758546295245 GRS(ph)PQPPAEEDEDDFDDTLVAIDTYNCDLHFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFK 32 1 M0R3F1;A0A0A0MRA5;B7Z4B8;Q9BUJ2-3;Q9BUJ2-4;Q9BUJ2-2;Q9BUJ2;M0R0K8;M0QYI8;M0QYZ0 M0R3F1 HNRNPUL1 Heterogeneous nuclear ribonucleoprotein U-like protein 1 1 GRS(0.999)PQPPAEEDEDDFDDT(0.001)LVAIDTYNCDLHFK 116.05 7.8781e-18 3129000.0 15690.0 13319.0 17521.0 18488.0 21611.0 15934.0 18512.0 16333.0 17528.0 14078.0 True False 18346.007108374375 14641.222297795506 17938.76708876252 17452.177298904728 17376.47968586156 15098.392989796133 16758.409344726282 15904.276056243965 17784.313840281866 16630.229958613327 1.1031721842711135 0.8803980663064944 1.0786842475062386 1.0494248932418213 1.0448730852853736 0.9078884072782285 1.007707613570705 0.9563473322872864 1.069396748243448 1.0 14.021520497534661 GRS(ph)SESSCGVDGDYEDAELNPR ddPTM_PC-9_AZD4547_30min_R2 2 GRSSESSCGVDGDYEDAELNPR 22 1 P11274-2;P11274 P11274-2 BCR Breakpoint cluster region protein 1 GRS(0.329)S(0.329)ES(0.329)S(0.012)CGVDGDYEDAELNPR;GRS(0.298)S(0.298)ES(0.298)S(0.107)CGVDGDYEDAELNPR 126.91 2.8195e-06 13870000.0 2713.1000000000004 8677.7 15077.4 18804.5 16873.1 10483.900000000001 12419.6 8089.4 6099.9 12031.9 True False 3575.809364014279 11482.596823327585 14877.463824601853 14469.41305162887 14530.56131590654 9828.340075673877 13524.920340046776 6839.369105919239 6422.328260807337 11610.666843225337 0.3079762267143781 0.98896962408559 1.2813617017426218 1.246217228261232 1.2514837874609175 0.8464922995709395 1.16487024584108 0.5890591124755178 0.553140344781719 1.0 13.503163213405525 -7.765553847108549 24.997655582810538 0.6783247399736445 1.03371685218458 0.17276367251024838 0.29359452660826957 165.29863810820387 1004251.0170384722 0.15742691889931545 0.0799354619029001 1.7157189691421285e-08 7.765553847108549 0.3553921122109356 GRS(ph)SVGNGNLHR ddPTM_PC-9_Lapatinib_30min_R1 2 GRSSVGNGNLHR 12 1 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 GRS(0.5)S(0.5)VGNGNLHR;GRS(0.979)S(0.021)VGNGNLHR 101.38 0.0022703000000000003 3330800.0 13779.7 11113.7 10250.7 7958.2 9507.099999999999 7178.799999999999 8193.099999999999 8594.2 11552.4 9207.4 True False 13583.198951112514 11087.966910473693 9407.927014846286 8543.472575776963 8947.911069677755 6871.779458600145 8617.298628853814 8993.517906669596 10251.247059834915 10798.886821910683 1.2578332540306403 1.0267694340472644 0.8711941489893039 0.7911438203465992 0.8285956892818488 0.6363414648126017 0.7979802706487785 0.8328189798620691 0.9492873875699281 1.0 13.398594982745562 -4.873935098210258 1.5647658337605896 0.8163670394396123 1.3751387335538674 0.6678987914273316 0.09269962721325636 0.502205211564858 1.3542148281786675 0.026663825517570964 0.4119985263488466 1.3367952748371268e-05 4.873935098210258 0.5587716941142551 GRSECDS(ph)SPEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GRSECDSSPEPK 12 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 GRSECDS(0.717)S(0.283)PEPK;GRSECDS(0.5)S(0.5)PEPK 83.823 0.0050027 17872200.0 59274.0 40508.0 52468.0 61721.0 62553.0 68564.0 62000.0 69957.0 57385.0 56061.0 True False 69307.91748513594 44529.36653195439 53719.03610599804 58262.97247218182 50296.18869046771 64968.3831399763 56126.911158871524 68120.7028755685 58224.14706324597 66224.41552136815 1.0465614069900377 0.6724010499962272 0.8111666321715578 0.8797808483999762 0.7594810508254165 0.9810336962356946 0.8475259572621137 1.0286342633494212 0.8791945780851657 1.0 16.01507558536753 -6.770108449891344 24.99997458907771 0.9428328637406501 0.8261956354417606 0.2322282789857414 0.10246192407474297 274.03391973508855 790257.6066295811 0.03393527720803441 0.030385001846020984 1.6978196283177227e-07 6.770108449891344 -0.11663722829888956 GRSECDSS(ph)PEPK ddPTM_PC-9_AZD4547_30min_R2 2 GRSECDSSPEPK 12 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 GRSECDS(0.049)S(0.951)PEPK;GRSECDS(0.058)S(0.942)PEPK 93.228 0.0025627 44358000.0 80120.0 71720.0 88676.0 111580.0 104985.0 91485.0 88794.0 82744.0 79479.0 89933.0 True False 105596.49340047305 94902.08743895897 87500.09830013086 85856.95489381527 90409.64492301056 85764.42848777882 96696.4939832293 69957.8160679633 83680.09768040563 86784.47304347463 1.2167671208601398 1.0935376353719153 1.0082460056685225 0.9893123952115868 1.041772125270841 0.9882462320744309 1.1142142204952867 0.8061098214299 0.9642289080730619 1.0 16.405149326977778 -1.522878745289066 0.5790677998562302 0.9720554974008998 14.264758447927004 0.5026996006280466 0.07218276086528211 131.95924806060785 1.0988967803963923 0.034658189049306086 2204.732350231626 0.029999999999397065 1.522878745289066 13.292702950526104 GRSECDSS(ph)PEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GRSECDSSPEPK 12 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 GRSECDS(0.283)S(0.717)PEPK;GRSECDS(0.388)S(0.611)PEPK 76.759 0.0086366 18406300.0 50923.0 35666.0 44034.0 61336.0 52959.0 56056.0 57751.0 56901.0 49617.0 43611.0 True False 59543.258124904285 39206.68477161758 45083.93755987495 57899.54277399504 42582.064119362476 53116.324679051846 52280.4071989676 55407.40904159302 50342.55475885814 51517.32907551398 1.155790860928095 0.7610387703552821 0.875121796275405 1.1238847939714813 0.8265580705270218 1.0310380144357651 1.0148120668743346 1.075510125153751 0.9771965212922071 1.0 15.652770178176725 GRSECDSS(ph)PEPK ddPTM_PC-9_Lapatinib_30min_R1 2 GRSECDSSPEPK 12 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 GRS(0.004)ECDS(0.387)S(0.608)PEPK;GRSECDS(0.056)S(0.944)PEPK 82.529 0.005668199999999999 45065000.0 124197.0 129035.0 132788.0 139134.0 133226.0 120571.0 112937.0 125754.0 133883.0 113847.0 True False 122425.92800505938 128736.22738538696 121870.68321650279 149366.378497418 125389.90861239373 115414.45939472859 118784.3252550151 131596.98992754723 118803.68668950848 133525.30225840825 0.9168743746270013 0.9641335777412949 0.9127160257660337 1.118637261785432 0.9390722693870388 0.8643639628043666 0.8896016204114985 0.9855584499847886 0.8897466224011282 1.0 17.026753624468867 -6.509494750962372 24.970998095027653 0.9203560082229542 0.9794776733987434 0.12089958232254994 0.06602236195517328 1251.6171372298074 2335192.929416337 0.021014146575280546 0.02283315405331011 3.093892709113746e-07 6.509494750962372 0.059121665175789206 GRSS(ph)VGNGNLHR ddPTM_PC-9_AZD4547_30min_R2 2 GRSSVGNGNLHR 12 1 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 GRS(0.03)S(0.97)VGNGNLHR;GRS(0.08)S(0.92)VGNGNLHR 110.51 0.00055871 7010600.0 2413.5 3817.5 6081.5 9395.3 11160.8 10002.599999999999 3445.45 11276.2 7835.1 9078.0 True False 3180.9427960814046 5051.4322197187075 6000.85533641849 7229.3587409380125 9611.3155694312 9377.135840759207 3752.0883752789264 9533.72239129807 8249.247390326329 8760.181983128154 0.363113780308195 0.576635534449811 0.6850149172672391 0.8252521186045609 1.097159349879067 1.070427059485669 0.4283116928969439 1.0883018651507161 0.9416753448974154 1.0 13.096745125199659 -5.304070276451794 1.307343611744352 0.9231426399407573 0.3584619252289473 0.5057847761326892 0.1855746709415671 0.5678577031771945 1.5182902876209512 0.060294318934879104 0.3325826431654278 4.965119706185111e-06 5.304070276451794 -0.56468071471181 GRSS(ph)VGNGNLHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GRSSVGNGNLHR 12 1 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 GRS(0.015)S(0.985)VGNGNLHR;GRS(0.197)S(0.803)VGNGNLHR 88.22399999999999 0.0038459 5700600.0 3022.8 3594.3999999999996 6139.099999999999 4783.29 8264.8 7254.8 4690.9 4966.4 2412.7 3573.5200000000004 True False 3534.5003369785877 3951.2282774379605 6285.479426666397 4515.297768935414 6645.3717693632225 6874.345516654507 4246.543992825006 4836.037262335766 2447.981173120041 4221.370888031245 0.8372873245987161 0.9360059521518913 1.4889664029492102 1.0696283005450984 1.5742212531489925 1.628462814330098 1.005963253516798 1.145608237373141 0.5799019413481875 1.0 12.04349587416068 -7.958040471078283 2.3429714010645384 0.8051842032439085 1.2485721500041764 0.25772608318624457 0.27739270860828724 0.4287187099888073 4.460641620231062 0.22561349689644242 0.08058615013805062 1.1014366639671224e-08 7.958040471078283 0.44338794676026794 GRSS(ph)VGNGNLHR ddPTM_PC-9_Lapatinib_30min_R1 2 GRSSVGNGNLHR 12 1 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 GRS(0.161)S(0.839)VGNGNLHR;GRS(0.264)S(0.736)VGNGNLHR 73.415 0.010717 9437500.0 4004.8 3979.8999999999996 4705.2 2250.8 3584.0 1263.97 2953.5099999999998 4163.700000000001 5826.799999999999 3170.8 True False 3947.690817609628 3970.684786074328 4318.3566185972395 2416.3313404486917 3373.196166415107 1209.9129495579812 3106.4282961645795 4357.1607023341585 5170.524425075839 3718.8685551745775 1.0615300753549513 1.0677131302609133 1.1612017350246249 0.6497490579726231 0.9070490436456841 0.325344370635112 0.8353154326581871 1.171636113965748 1.3903487978571791 1.0 11.860648040907469 -9.53218907296517 10.054359946413982 1.0000199243769243 0.9361080041849343 0.0 0.28487948507053823 0.0 0.0 0.29738178227582923 0.07212567643868693 2.9363710051770845e-10 9.53218907296517 -0.06391192019198999 GRSTRS(ph)WWGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GRSTRSWWGVR 11 2 O43741-2 O43741-2 PRKAB2 5-AMP-activated protein kinase subunit beta-2 1 GRST(0.152)RS(0.847)WWGVR 48.74100000000001 0.038393000000000004 2726200.0 3512.2 2969.0 4652.2 4997.4 6901.3 5098.9 3928.9 4709.7 4657.1 3395.1 True False 4106.746090887987 3263.7426985625707 4763.126091566752 4717.411879789399 5549.039806396574 4831.504707899555 3556.726149227265 4586.075365339633 4725.201277132399 4010.6047544031885 1.023971780410235 0.8137781951660412 1.1876328841273576 1.176234550315689 1.383591788820466 1.2046823368957291 0.8868303827053473 1.1434872409964216 1.178176750512417 1.0 11.969604080044352 -5.272340021406095 24.67986670612297 1.1527405111283262 0.9188749849780412 0.3179428432749746 0.13214419788475426 632.3184755459682 1431617.9074906004 0.036397363167216534 0.07697806901589985 5.3414599766904505e-06 5.272340021406095 -0.233865526150285 GRSYDS(ph)SMESR ddPTM_PC-9_Lapatinib_30min_R1 1 GRSYDSSMESR 11 1 Q9HCG8;B7WP74 Q9HCG8 CWC22 Pre-mRNA-splicing factor CWC22 homolog 1 GRS(0.252)YDS(0.575)S(0.173)MESR 92.943 0.016000999999999998 3922600.0 10382.0 7957.6 9536.2 8019.1 8869.3 7669.9 7625.7 8925.0 8642.3 6666.4 True False 10233.95077617438 7939.174666113488 8752.170446796526 8608.851364933404 8347.625211714709 7341.876256410159 8020.521433163333 9339.688082314371 7668.913166546461 7818.678357580357 1.3089105739018374 1.0154113397459696 1.1193925682223684 1.1010622219274384 1.0676516963537102 0.9390175577809862 1.0258154980102596 1.1945354003799589 0.9808452037307948 1.0 12.932709044610464 -4.755882182369195 24.997050776165143 1.0555834130351256 1.3089109769971705 0.5449369699736886 0.0709620203073655 144.41587554327398 649534.6103819084 0.017782296518391777 0.1520670718572676 1.7543563680696366e-05 4.755882182369195 0.2533275639620449 GRTS(ph)STNEDEDLNPEQK ddPTM_PC-9_AZD4547_30min_R2 1 GRTSSTNEDEDLNPEQK 17 1 Q99081;Q99081-3;B4DZP2;F5GY10;B4DGI9;Q99081-4;Q99081-2 Q99081 TCF12 Transcription factor 12 1 GRT(0.115)S(0.385)S(0.385)T(0.115)NEDEDLNPEQK 132.6 1.1177e-05 18640000.0 33705.0 31223.0 40501.0 51321.0 50732.0 33815.0 34960.0 39611.0 33805.0 30688.0 True False 44422.488892448215 41315.22415095671 39963.93027711671 39489.73635154593 43688.737498063216 31700.54270442411 38071.37227350604 33490.030120227355 35591.86328572468 29613.622460700233 1.5000694005402613 1.3951425296174247 1.3495117096921259 1.3334990139741307 1.475291905137301 1.0704716299565646 1.2856033510939078 1.130899475897332 1.201874689020503 1.0 14.853973357279896 -4.400607333938222 0.12610121439202449 0.8645330272270102 2.094615064250229 0.6883895637130961 0.08963871023001035 22.795175500835892 0.4225708312799278 0.7193710680975571 4.835491390246886 3.9755083142278945e-05 4.400607333938222 1.2300820370232186 GRTSS(ph)TNEDEDLNPEQK ddPTM_PC-9_AZD4547_30min_R2 1 GRTSSTNEDEDLNPEQK 17 1 Q99081;Q99081-3;B4DZP2;F5GY10;B4DGI9;Q99081-4;Q99081-2 Q99081 TCF12 Transcription factor 12 1 GRT(0.003)S(0.009)S(0.938)T(0.05)NEDEDLNPEQK 134.83 0.00016566 4942400.0 21479.0 12836.0 20548.0 28649.0 25452.0 24654.0 17352.0 20494.0 17198.0 23741.0 True False 28308.875209046008 16984.98597833905 20275.52009417531 22044.415672637704 21918.429133499663 23112.381482622262 18896.29438472186 17327.12320526973 18107.05116958714 22909.83481619799 1.2356647455629284 0.7413840437788805 0.885013805505043 0.9622249941781158 0.956725760327291 1.0088410356534332 0.8248114635624336 0.7563181203305271 0.7903614895025289 1.0 14.48367943615314 -7.281510835720988 22.153221640082013 0.8225658439859185 0.9506777925252509 0.16233307083432735 0.13030728468298455 335.1703202349975 369928.86200827104 0.05276847780405752 0.03565416410844179 5.229849174569733e-08 7.281510835720988 0.1281119485393324 GRTSS(ph)TNEDEDLNPEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GRTSSTNEDEDLNPEQK 17 1 Q99081;Q99081-3;B4DZP2;F5GY10;B4DGI9;Q99081-4;Q99081-2 Q99081 TCF12 Transcription factor 12 1 GRT(0.071)S(0.178)S(0.375)T(0.375)NEDEDLNPEQK 62.847 0.012957 9046400.0 31156.0 16890.0 25940.0 42337.0 42244.0 55615.0 52410.0 51165.0 41774.0 45367.0 True False 36430.09544095042 18566.72757787867 26558.507977997815 39964.99514840595 33966.59145109135 52698.45149538793 47445.345384458975 49821.97296379862 42384.86572135639 53591.6779750256 0.6797715021710516 0.34644796131464667 0.4955714950812776 0.7457313646165388 0.6338034697648431 0.9833327390858349 0.8853118091687501 0.9296587613288818 0.7908852143257816 1.0 15.709721367614883 -6.275036177488985 1.2451772593165311 0.911195412904571 0.4936920763950423 0.6833413912822759 0.11466787262529131 0.25103919554180903 0.796177225324021 0.045276059896013875 0.06450880063177626 5.308402224713144e-07 6.275036177488985 -0.41750333650952864 GRTSS(ph)TNEDEDLNPEQK ddPTM_PC-9_Lapatinib_30min_R1 1 GRTSSTNEDEDLNPEQK 17 1 Q99081;Q99081-3;B4DZP2;F5GY10;B4DGI9;Q99081-4;Q99081-2 Q99081 TCF12 Transcription factor 12 1 GRT(0.043)S(0.043)S(0.457)T(0.457)NEDEDLNPEQK 120.9 3.7343000000000005e-05 13856000.0 72352.0 39364.0 61952.0 48773.0 55048.0 67051.0 46876.0 52549.0 69933.0 55366.0 True False 71320.24721226832 39272.855076516935 56858.54570163569 52359.929121958456 51810.18486853204 64183.38503351517 49303.00991397049 54990.61837955604 62056.40911286267 64935.939329442284 1.0983170174906727 0.6047938242222427 0.8756098131294103 0.8063320506741048 0.7978661031710222 0.9884108198988368 0.75925612878008 0.8468441197188168 0.9556558317887607 1.0 15.98672955024609 -8.346130270083531 3.3112372689276155 0.9960596977986942 0.8382921396135097 0.15111556754446054 0.12453572422119195 0.4117720888938189 8.186119686602956 0.10954810968373109 0.029711139477268396 4.50681498764895e-09 8.346130270083531 -0.1577675581851845 GRWES(ph)QQDVSQTTVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GRWESQQDVSQTTVSR 16 1 Q9NQT8;H0YBA8 Q9NQT8 KIF13B Kinesin-like protein KIF13B 1 GRWES(0.995)QQDVS(0.005)QTTVSR;GRWES(1)QQDVSQTTVSR 86.772 0.021255 3309100.0 27500.4 16716.4 24554.7 32756.0 33271.7 27995.0 27396.6 28868.9 24216.7 22464.6 True False 32155.67456234152 18375.893717161114 25140.177172218333 30920.78751638485 26752.34922789691 26526.892917619098 24801.395713792568 28111.12196412794 24570.823424004666 26537.254150324236 1.2117182275223692 0.6924564844979109 0.9473541245001479 1.1651841347725518 1.008105400670101 0.9996095589752261 0.9345878655455973 1.0593078622561436 0.9258992390403156 1.0 14.695731480150155 -5.53804785369652 24.97219536823338 1.0150858121643414 0.9190417881960062 0.0332664885623245 0.1328290181679613 537.5423621997061 884927.5906047936 0.03427863698729898 0.05939752286045497 2.8970243550880447e-06 5.53804785369652 -0.09604402396833511 GRWES(ph)QQDVSQTTVSR ddPTM_PC-9_Lapatinib_30min_R1 2 GRWESQQDVSQTTVSR 16 1 Q9NQT8;H0YBA8 Q9NQT8 KIF13B Kinesin-like protein KIF13B 1 GRWES(1)QQDVSQTTVSR;GRWES(1)QQDVSQTTVSR 97.49 0.001029 27307000.0 95040.0 67424.0 82110.0 70375.0 66265.0 71864.0 68655.0 64589.0 78534.0 49282.0 True False 93684.71217179844 67267.88387051817 75359.2327537659 75550.61226411804 62367.42298200257 68790.54424316608 72209.6199685051 67590.040733737 69688.67392031742 57800.32803586275 1.6208335723228229 1.1637976142415867 1.303785554763782 1.307096600165348 1.0790150350583845 1.1901410697960804 1.2492942933421063 1.169371230761876 1.205679557338817 1.0 15.818790060067263 -2.9409473805659503 1.6840539491460766 1.192085390621312 199.88487446101396 0.6550631631038486 0.09294304938948887 385.9042749411368 3.055546690743211 0.024545371870147513 294557.76063948986 0.0011456517410317413 2.9409473805659503 198.69278907039265 GS(ph)ATPSGQESR ddPTM_PC-9_AZD4547_30min_R2 1 GSATPSGQESR 11 0 Q14781 Q14781 CBX2 Chromobox protein homolog 2 1 GS(0.391)AT(0.295)PS(0.007)GQES(0.307)R 79.744 0.016939 2816000.0 12863.0 11171.0 16005.0 24782.0 21688.0 19308.0 12718.0 18406.0 14811.0 15704.0 True False 16953.16643297912 14781.807289188668 15792.76324251877 19068.89277808327 18676.99556213031 18100.667707733865 13849.877361969393 15561.775627803008 15593.879222744215 15154.207739925589 1.118710177656728 0.9754259373285621 1.0421371749386033 1.2583233056680339 1.2324626851276106 1.1944318052368696 0.9139294907169723 1.0268947011201142 1.0290131619127973 1.0 13.887430809727936 -7.256083760578115 24.988629894092313 0.9947005632469313 1.1351282891325198 0.41221944413078193 0.08447219974476565 539.0077429839708 2514950.5269710314 0.037842446354064245 0.028412226606356533 5.545187549082173e-08 7.256083760578115 0.1404277258855885 GS(ph)DPASGEVEASQLR ddPTM_PC-9_AZD4547_30min_R2 1 GSDPASGEVEASQLR 15 0 Q8WWA1-3;Q8WWA1-2;Q8WWA1 Q8WWA1-3 TMEM40 Transmembrane protein 40 1 GS(1)DPASGEVEASQLR 113.43 0.0027099 0.0 2733.2 11325.0 14590.0 15177.0 16631.0 6370.5 8670.3 12062.0 9691.4 10587.0 True False 3602.3007459083065 14985.584777554523 14396.527067063347 11678.177132312563 14322.072721956336 5972.151627932392 9441.939903403301 10198.095057185694 10203.667618614767 10216.352352431997 0.35260145907661267 1.4668234082575677 1.4091650885197065 1.1430867622270857 1.4018773264556577 0.5845678987873519 0.9241987333331991 0.9982129340672204 0.9987583891608622 1.0 13.318592567762645 -6.748391745912298 24.999283126168827 0.9024765285857624 1.1855409083288755 0.13481159677694643 0.3163864968882108 440.2589213385845 843535.3409040355 0.10347051667373286 0.10286223492000092 1.7848768390795287e-07 6.748391745912298 0.28306437974311305 GS(ph)DPASGEVEASQLR ddPTM_PC-9_Lapatinib_30min_R1 1 GSDPASGEVEASQLR 15 0 Q8WWA1-3;Q8WWA1-2;Q8WWA1 Q8WWA1-3 TMEM40 Transmembrane protein 40 1 GS(1)DPASGEVEASQLR 142.19 1.1687000000000001e-06 0.0 9269.0 10185.0 8359.1 5728.8 6282.8 7032.7 7898.0 4996.9 9163.6 4225.5 True False 9136.822360273574 10161.417258264535 7671.847065059125 6150.115062716577 5913.258056460057 6731.927815024411 8306.919794789199 5229.074216080299 8131.498871014099 4955.872044875164 1.843635646267725 2.0503792604517286 1.5480317077581804 1.2409753534852404 1.1931821489569974 1.3583740165337512 1.6761772135298232 1.0551269622644217 1.640780633031644 1.0 12.27492322383408 -5.4479549430121965 3.690621462733122 1.3259622341323556 1.9420698512048342 0.5837818010218884 0.2127915644736862 0.15540865474714696 4.017414025742689 0.05494017544541054 0.12088099145670425 3.564881162758868e-06 5.4479549430121965 0.6161076170724786 GS(ph)EDSPPKHAGNNESHSSR ddPTM_PC-9_AZD4547_30min_R2 1 GSEDSPPKHAGNNESHSSR 19 1 P48651;P48651-2 P48651 PTDSS1 Phosphatidylserine synthase 1 1 GS(0.928)EDS(0.072)PPKHAGNNESHSSR 55.18899999999999 0.013266 2112700.0 2366.0 2038.6 16640.0 28050.0 18183.0 9450.7 4310.8 18172.0 6983.8 9759.9 True False 3118.3387841427834 2697.5375830042058 16419.342727617142 21583.505868179946 15658.604311426378 8859.746235005201 4694.452848873848 15363.934951017935 7352.949410289722 9418.208871682355 0.33109679628349137 0.286417260410827 1.743361498064142 2.2916784032126194 1.6625883461245976 0.9407039444244778 0.498444334037719 1.6313011486942641 0.7807163241407579 1.0 13.201237002924803 -5.24779653619394 24.16658178153284 1.3453963556185646 0.3087566790857996 0.3887541903034992 0.5056127467140104 551.0928659192206 976184.5121595637 0.14138217599938974 0.3692307088411282 5.652017056835029e-06 5.24779653619394 -1.036639676532765 GS(ph)EMDNNCSPTRK ddPTM_PC-9_AZD4547_30min_R2 1 GSEMDNNCSPTRK 13 1 O95243-3;O95243-5;O95243-2;O95243 O95243-3 MBD4 Methyl-CpG-binding domain protein 4 1 GS(0.503)EMDNNCS(0.495)PT(0.002)RK 107.53 0.00074969 0.0 7410.6 8805.8 8402.6 11259.0 10397.0 10007.0 7866.3 9655.7 7349.9 7459.1 True False 9767.01664994442 11652.102643195554 8291.176033838696 8663.41149981598 8953.556015283511 9381.260708063644 8566.38546095768 8163.633430912603 7738.4007088817625 7197.959179373342 1.356914704091826 1.6188064356611138 1.151878723846907 1.2035927523237526 1.243902027249759 1.3033222993187885 1.190113092820217 1.1341594509602837 1.0750826055053389 1.0 12.813372205223889 -1.5228787452867587 0.1492321037524079 0.9547268700471171 2.8232847822544063 0.5804473538497974 0.10589402891821102 50.56126628407776 0.49705899309792706 0.391775482788969 20.420143052585132 0.029999999999556444 1.5228787452867587 1.8685579122072893 GS(ph)ESPNSFLDQESR ddPTM_PC-9_AZD4547_30min_R2 1 GSESPNSFLDQESR 14 0 Q5T4Y8;A0A5H1ZRR2;G9CGD6-3;G9CGD6;G9CGD6-2;Q6P9H4 Q5T4Y8 CNKSR3 Connector enhancer of kinase suppressor of ras 3 1 GS(0.661)ES(0.164)PNS(0.169)FLDQES(0.006)R 83.292 0.0082384 3814800.0 5635.5 6949.4 9767.1 9435.7 11887.0 9182.8 8724.7 11583.0 8323.0 9491.6 True False 7427.471774318109 9195.657647076145 9637.581872290237 7260.445145111789 10236.695234555656 8608.598064355638 9501.18139801654 9793.1135008607 8762.936788258738 9159.301973018193 0.810921159297753 1.0039692625229575 1.052217942009225 0.792685421498262 1.1176283154230844 0.9398749041919527 1.037325925709783 1.069198671439113 0.9567253939298996 1.0 13.161021939923481 -6.2788660909871 24.888277006051418 1.0204329445122646 0.9311120166000973 0.24963863644530904 0.08755499387237661 1280.4889921579436 1828749.5205932811 0.026541731078098294 0.030164589981212832 5.261794819295844e-07 6.2788660909871 -0.08932092791216728 GS(ph)ETPGATPGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSETPGATPGSK 12 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 GS(0.99)ET(0.01)PGATPGSK 123.26 0.0003632 10240000.0 30453.0 31991.0 33884.0 36971.0 39523.0 32024.0 41037.0 35262.0 28974.0 27538.0 True False 35608.091425833314 35166.85505884645 34691.92306578557 34899.6347315992 31778.751868229425 30344.605064969965 37149.67827784859 34336.40986317732 29397.68993657732 32530.421409311937 1.0946089808612312 1.08104517357343 1.0664455473624728 1.072830698762761 0.9768933352684037 0.9328070080359834 1.141998064224719 1.0555169092690702 0.903698404846429 1.0 14.989501891174932 -6.1832714849121935 7.150601465334312 1.008237233109837 1.0785422175289092 0.2674998310845098 0.061829428858990364 0.44492117143189686 35.35021196230303 0.01918674988783931 0.024829462946652694 6.557352268438136e-07 6.1832714849121935 0.07030498441907218 GS(ph)ETPGATPGSK ddPTM_PC-9_Lapatinib_30min_R1 1 GSETPGATPGSK 12 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 GS(0.713)ET(0.287)PGATPGSK 93.62299999999999 0.0052169 8072500.0 20413.0 19776.0 21593.0 18559.0 24334.0 21641.0 21582.0 18225.0 23469.0 19906.0 True False 20121.906876714256 19730.20988703382 19817.70689139041 19923.890771009093 22902.721962484717 20715.464877634964 22699.410358462967 19071.80003363355 20825.674080473826 23346.725576922276 0.8618727628599155 0.8450953784515589 0.8488430990502488 0.8533912263355432 0.9809821890022793 0.8872963709357061 0.972273832733993 0.8168939995802068 0.892016913115197 1.0 14.510932602923567 -6.059373373925913 24.660539215434405 0.9163285840210265 0.8512302394797565 0.3213536927298979 0.05078250380561044 289.8657107230918 120393.95741927053 0.014787055434856406 0.019090060107679406 8.722211753986021e-07 6.059373373925913 -0.06509834454126995 GS(ph)FEAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSFEAPR 7 0 Q96IF1 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 GS(1)FEAPR 88.177 0.017446 12492000.0 48155.0 76139.0 70881.0 65446.0 58663.0 46811.0 49680.0 45029.0 42357.0 40511.0 True False 56306.69039539634 83697.57673487904 72571.0718576895 61779.2727987948 47168.40626586907 44356.14875394418 44973.95074794739 43847.03646216923 42976.390993428766 47855.323615100424 1.176602437134688 1.7489710738988469 1.5164681037657886 1.2909592524268454 0.9856459574956337 0.9268801337694412 0.9397899199192995 0.91624156206382 0.8980482785799793 1.0 15.546391804279407 -6.121222234262469 2.342027091153749 0.9316790109072497 1.5063669568432245 0.7729475544520541 0.13258700353220937 0.12883395539861492 1.386629370310863 0.041223788988160655 0.05804128397711912 7.564457126344163e-07 6.121222234262469 0.5746879459359748 GS(ph)FEAPR ddPTM_PC-9_Lapatinib_30min_R1 2 GSFEAPR 7 0 Q96IF1 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 GS(1)FEAPR;GS(1)FEAPR 93.598 0.013808 26605000.0 98926.0 150643.0 156328.0 140799.0 148805.0 148125.0 136306.0 138387.0 141685.0 143350.0 True False 97515.29709919357 150294.19538897814 143475.3152835307 151153.82815169482 140052.58246188637 141790.03904623992 143363.25772961977 144816.96522658173 125726.94329080635 168127.85649813132 0.5800067825183831 0.8939279814743168 0.8533702758836124 0.8990409519280039 0.8330123596350197 0.843346498311039 0.8527037738758847 0.8613502143125896 0.7478055445987545 1.0 17.35919925375324 -14.52287874297807 0.020251763610457846 2.036692592472869 7.461302067049381e-14 0.2677476338402335 0.08926605296076041 5249.654379303577 8.017885956804923 545.9098819479789 295.78439801770384 3.000000015903497e-15 14.52287874297807 -2.0366925924727943 GS(ph)FKDDPQLYQEIQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSFKDDPQLYQEIQER 16 1 Q5VV41 Q5VV41 ARHGEF16 Rho guanine nucleotide exchange factor 16 1 GS(0.97)FKDDPQLY(0.03)QEIQER;GS(1)FKDDPQLYQEIQER 98.227 0.01236 8943600.0 62584.0 68317.0 51664.5 47572.6 57929.0 37389.0 39313.7 45515.4 29066.7 30090.6 True False 73178.235109656 75099.06026867611 52896.37761870737 44907.26145445014 46578.22829680599 35428.25502042723 35589.62172946013 44320.66897755265 29491.745498706146 35545.78758294147 2.058703438175455 2.1127414913354285 1.4881194429939286 1.2633638050546747 1.3103726619679408 0.996693488300407 1.0012331741536569 1.2468613580198815 0.8296832762501322 1.0 15.11739098037071 -5.424205243883836 0.9778274334471336 1.0417605340008098 2.2989261662635863 0.8996071566482701 0.13288090202020658 0.24608326376099132 0.3559798616029102 0.047717024968667185 0.2639418014548887 3.7652581402812454e-06 5.424205243883836 1.2571656322627764 up GS(ph)FKDDPQLYQEIQER ddPTM_PC-9_Lapatinib_30min_R1 3 GSFKDDPQLYQEIQER 16 1 Q5VV41 Q5VV41 ARHGEF16 Rho guanine nucleotide exchange factor 16 1 GS(0.999)FKDDPQLY(0.001)QEIQER;GS(1)FKDDPQLYQEIQER;GS(1)FKDDPQLYQEIQER 105.9 0.0023909 17702700.0 84301.8 129360.0 108245.0 115968.0 100829.9 80526.3 86989.2 84316.0 100879.2 113333.0 True False 83099.64087294319 129060.4748678545 99345.51393778312 124496.67357790716 94899.28352121051 77082.37786497369 91493.07513457545 88233.6291706913 89517.1221909298 132922.4580432702 0.625173820107147 0.9709455931505683 0.7473944990201973 0.9366112800696164 0.7139446931557494 0.5799048482829071 0.6883191635290987 0.6637977544920862 0.673453707587843 1.0 17.02022535158968 -4.4861485668557295 16.681387217149375 0.7602714613904192 0.071398580599681 0.08771465836256664 0.13777330180001462 3904307.3753740247 51910974.586276315 0.034927499171545605 80616973.08361903 3.2647612955754195e-05 4.4861485668557295 -0.6888728807907383 GS(ph)FSGQAQPLR ddPTM_PC-9_AZD4547_30min_R2 2 GSFSGQAQPLR 11 0 Q92609;Q92609-2 Q92609 TBC1D5 TBC1 domain family member 5 1 GS(0.977)FS(0.023)GQAQPLR;GS(0.994)FS(0.006)GQAQPLR 88.09200000000001 0.010015999999999999 10920500.0 14727.8 22061.3 23344.0 29734.0 24723.0 24676.0 23050.0 28765.0 24979.0 36141.0 True False 19410.93404272953 29192.183792764987 23034.443307301364 22879.28568572061 21290.638200043686 23133.005819144455 25101.405346233227 24320.030203941813 26299.338944360807 34875.71459046426 0.5565745181329382 0.8370347141430826 0.6604722964902189 0.6560234235881801 0.6104717408676404 0.6632984037972801 0.719738810831319 0.6973342479007272 0.7540874575098051 1.0 15.08993515708073 -9.04726369340054 0.8859295588089338 1.0019360743028243 0.6719343648241984 0.6758942054297306 0.06810886679875221 1.0727160123056558 1.2687674448497128 0.06778483901301012 0.02166199685849944 8.968840622234557e-10 9.04726369340054 -0.33000170947862584 GS(ph)FSGQAQPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSFSGQAQPLR 11 0 Q92609;Q92609-2 Q92609 TBC1D5 TBC1 domain family member 5 1 GS(1)FSGQAQPLR 74.392 0.022887 5152900.0 10779.0 13777.0 12289.0 10318.0 15843.0 12452.0 8092.4 10001.0 3816.1 7182.8 True False 12603.671805045728 15144.689510978948 12582.016366292039 9739.91591140734 12738.677879927096 11798.995199506795 7325.8292880976105 9738.484346935413 3871.9032431480878 8484.984780986484 1.4854088876256528 1.7848811638314088 1.4828566804841368 1.1479002217226082 1.5013200622907974 1.39057352535817 0.8633874399531796 1.1477315043343181 0.45632412350631596 1.0 13.050696356755893 -7.267851197589588 1.0069660419254092 0.7808949777660419 1.522216496985963 0.6351190270530194 0.22076429600817532 0.3533578404311907 0.6955101462955056 0.1610733190019539 0.0913108136850141 5.39695506825772e-08 7.267851197589588 0.7413215192199212 GS(ph)FSQADVHR ddPTM_PC-9_AZD4547_30min_R2 1 GSFSQADVHR 10 0 Q04206;Q04206-4;Q04206-3;Q04206-2;A0A087X0W8;E9PKH5;Q2TAM5 Q04206 RELA Transcription factor p65 1 GS(1)FSQADVHR 162.72 0.00036556 5073000.0 25476.0 25726.0 39879.0 44811.0 41063.0 32740.0 28633.0 36472.0 31254.0 35012.0 True False 33576.838066281285 34041.426400650555 39350.17840352428 34480.51627304856 35362.111248974405 30692.762624363328 31181.28153052911 30836.090443183242 32906.022633694396 33786.24053682342 0.9938021375798262 1.0075529523194215 1.1646805853003017 1.020549067466339 1.0466423812508365 0.9084397120452473 0.9228988202030002 0.9126819069903671 0.9739474446063427 1.0 15.044148207392793 -6.751360518284899 24.606078070697773 0.9368427750251835 1.0495813653891308 0.5033586044702618 0.050919114692695826 135.1590012907079 329970.4678160302 0.017174677237542634 0.01697856135066996 1.7727172947039665e-07 6.751360518284899 0.11273859036394729 GS(ph)FSQADVHR ddPTM_PC-9_Lapatinib_30min_R1 1 GSFSQADVHR 10 0 Q04206;Q04206-4;Q04206-3;Q04206-2;A0A087X0W8;E9PKH5;Q2TAM5 Q04206 RELA Transcription factor p65 1 GS(0.985)FS(0.015)QADVHR 122.39 0.0003075 4190200.0 35389.0 30140.0 32964.0 32294.0 32172.0 32095.0 22815.0 28118.0 35792.0 28316.0 True False 34884.34637045223 30070.2126817961 30253.827164719754 34669.00848962595 30279.70621258561 30722.371667099207 23996.24906534764 29424.464929805672 31760.728053530976 33210.38287130165 1.050404823866006 0.9054461310586368 0.9109749587037502 1.0439207709220588 0.9117542043982713 0.9250833327082048 0.7225526173046235 0.886001978472596 0.9563493494372396 1.0 15.019346734830425 -6.651283951043672 2.8564107391637736 0.8784766607950945 0.9678649141248168 0.14889802981844047 0.08217763952985417 0.45201985208776996 7.447076581959838 0.029629798991743925 0.029297255553739677 2.2321123427252526e-07 6.651283951043672 0.08938825332972233 GS(ph)FSSENYWR ddPTM_PC-9_AZD4547_30min_R2 2 GSFSSENYWR 10 0 Q6P6C2-3;Q6P6C2;K7ER58;Q6P6C2-1 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 GS(1)FSSENYWR;GS(0.997)FS(0.002)SENYWR 82.85 0.014349 11128300.0 12219.3 23482.0 19434.9 31534.0 24747.5 20536.4 23273.0 25898.0 25631.0 18980.7 True False 16104.78322277088 31072.09728446228 19177.180527461922 24264.32349544337 21311.73679794448 19252.255661544747 25344.251914225002 21896.059176835915 26985.802333276428 18316.19147027545 0.8792648432894268 1.6964278482722697 1.0470069915235234 1.324747207126595 1.1635462990507808 1.0511058312962274 1.3837075221317208 1.1954482574813696 1.4733304342810847 1.0 14.16083193111999 -4.5036259888951236 19.040920578316697 1.2572718496819177 6.691577348430012e-05 0.23407308977497343 0.2062981784572088 8222009.610231314 192357216.42423397 0.047607345023023516 309437220.12731385 3.1359852483897556e-05 4.5036259888951236 -1.2572049339084335 GS(ph)FSSENYWR ddPTM_PC-9_Lapatinib_30min_R1 2 GSFSSENYWR 10 0 Q6P6C2-3;Q6P6C2;K7ER58;Q6P6C2-1 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 GS(0.893)FS(0.08)S(0.026)ENY(0.001)WR;GS(1)FSSENYWR 97.779 0.0050136 9452800.0 16315.8 21835.5 18403.7 13646.2 23071.0 18133.5 17575.0 22066.0 21724.2 12861.1 True False 16083.133700048724 21784.941241319113 16890.618826336395 14649.787070388715 21714.009139331196 17357.9724762531 18484.94750486455 23091.26691589344 19277.39183003236 15084.12399866146 1.0662292156625015 1.4442297904241752 1.1197613350192057 0.971205690942922 1.439527356130065 1.1507444832589164 1.225457143318689 1.5308324777721611 1.2779921347598975 1.0 13.880743294828662 -6.275996234856006 24.99109907861866 1.2890347285439103 1.1691620665417979 0.09036112338373414 0.1777155341531261 2054.1504678117085 3526543.175919656 0.05502695938744285 0.06265957290401533 5.296680358629181e-07 6.275996234856006 -0.11987266200211244 GS(ph)FWALHPSCGDMFENGSFLRRR ddPTM_PC-9_Lapatinib_30min_R1 1 GSFWALHPSCGDMFENGSFLRRR 23 2 Q99853 Q99853 FOXB1 Forkhead box protein B1 1 GS(0.982)FWALHPS(0.016)CGDMFENGS(0.002)FLRRR 42.172 0.028045999999999998 3702100.0 19772.0 19498.0 18691.0 18365.0 17260.0 19208.0 17686.0 15848.0 18667.0 18475.0 True False 19490.047654259277 19452.85357895355 17154.298129346476 19715.623363844057 16244.800734465614 18386.518616034944 18601.69454173739 16584.35593596842 16564.52588777557 21668.37913360992 0.8994695696471443 0.897753055685653 0.791674265230959 0.9098799334401098 0.7497007798459753 0.8485414853903647 0.8584718970919342 0.765371319825411 0.7644561591633894 1.0 14.40330361865887 -5.238029843635475 22.20796316185042 0.8284376121547187 0.8986114366663215 0.09881305105607174 0.0727985024759897 382.2654511538233 362636.37258371356 0.0174007133099221 0.04592877096985051 5.780563234495848e-06 5.238029843635475 0.07017382451160281 GS(ph)GDTSSLIDPDTSLSELR ddPTM_PC-9_Lapatinib_30min_R1 1 GSGDTSSLIDPDTSLSELR 19 0 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 GS(0.914)GDT(0.027)S(0.027)S(0.032)LIDPDTSLSELR 90.714 0.0052752 0.0 2415.9 3138.5 3026.3 3853.3 4211.7 4568.8 3487.3 4723.0 4015.9 2959.7 True False 2381.448822978201 3131.232996078865 2777.4892958558266 4136.68453623198 3963.976086520792 4373.403074392985 3667.8553305100536 4942.4478221591935 3563.587052698233 3471.2802014476456 0.6860433859488074 0.9020398280648826 0.8001339951460894 1.1916884538755579 1.141934922126907 1.259881893881434 1.0566290007301713 1.4238112555990206 1.026591587510594 1.0 11.761252108752071 -5.760416031492712 24.99910321042897 1.174327877965548 0.8066690619390875 0.6282345934445663 0.12675576801615493 15.741667123505593 384526.6235056972 0.032560661665214784 0.05253638440619926 1.736136903175944e-06 5.760416031492712 -0.36765881602646044 GS(ph)GEPTPQK ddPTM_PC-9_AZD4547_30min_R2 1 GSGEPTPQK 9 0 Q9H6A9;Q9H6A9-2 Q9H6A9 PCNXL3 Pecanex-like protein 3 1 GS(0.999)GEPT(0.001)PQK 77.288 0.023277000000000003 5327600.0 55351.0 76217.0 73727.0 84233.0 72964.0 62990.0 69102.0 71554.0 68702.0 60166.0 True False 72951.46662767843 100852.654745331 72749.33180763389 64814.383236877155 62834.20805031702 59051.22534235324 75251.94413168811 60496.97344734413 72333.44746208719 58059.606653105155 1.2564926087692814 1.7370537032382252 1.253011103611104 1.1163421003543905 1.0822361995274818 1.017079321518191 1.2961152937412033 1.041980422099684 1.2458480453418408 1.0 15.825247177460685 -5.483943274264054 6.1154458100101 1.1223028696541295 1.4997839900047587 0.5402147816860066 0.1397644120109543 0.13349898178977554 13.917568049347338 0.03435947088663239 0.07016763180799984 3.2813815035230936e-06 5.483943274264054 0.3774811203506292 GS(ph)GEPTPQK ddPTM_PC-9_Lapatinib_30min_R1 2 GSGEPTPQK 9 0 Q9H6A9;Q9H6A9-2 Q9H6A9 PCNXL3 Pecanex-like protein 3 1 GS(1)GEPTPQK;GS(1)GEPTPQK 104.43 0.0027033 7661300.0 185367.0 286160.0 165810.0 109920.0 151380.0 115910.0 114899.0 107169.0 167676.0 83397.0 True False 182723.63258785554 285497.4141016185 152177.74184510944 118003.88348237085 142476.12602453103 110952.79949940715 120847.90801487517 112148.46297966922 148790.5631734429 97812.06033048274 1.8681094332383719 2.9188365231955387 1.555817772685071 1.2064349026455934 1.4566314781954237 1.1343468190377046 1.235511322494997 1.1465709095662369 1.521188314311307 1.0 16.57772474151892 -5.440844335240911 5.335411530053683 1.2607079172376223 2.384042659762136 0.7287831672907021 0.2764875695171006 0.09739935530421832 4.666562652179188 0.06709040933187571 0.14182102564492013 3.6237286093702877e-06 5.440844335240911 1.1233347425245137 GS(ph)GFSLDVIDGPISQR ddPTM_PC-9_AZD4547_30min_R2 3 GSGFSLDVIDGPISQR 16 0 O43166-3;O43166-2;O43166 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 GS(1)GFSLDVIDGPISQR;GS(0.996)GFS(0.004)LDVIDGPISQR;GS(1)GFSLDVIDGPISQR 251.28 1.1251999999999999e-47 13812900.0 16830.9 23497.5 31976.0 25447.299999999996 31054.1 33725.8 33814.2 40496.0 32690.0 26748.699999999997 True False 22182.776095532026 31092.60735634324 31551.977347252767 19580.81814186579 26742.774247784513 31616.92039452511 36823.598293214745 34238.27370550421 34417.9266620423 25812.23615467063 0.8593899405928894 1.204568529825617 1.2223651278482337 0.7585866650426841 1.0360502704042365 1.2248811069708172 1.4265946612514486 1.3264357841894654 1.3333957761662003 1.0 14.65576750933892 -6.839931617607723 4.006565942652891 1.3012178730870587 1.0229807953107235 0.34831829936069847 0.16682782495133658 0.24305168967663354 7.5071555855895875 0.06085495293082937 0.05423518722856712 1.4456673822299305e-07 6.839931617607723 -0.2782370777763352 GS(ph)GFSLDVIDGPISQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GSGFSLDVIDGPISQR 16 0 O43166-3;O43166-2;O43166 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 GS(1)GFSLDVIDGPISQR;GS(0.997)GFS(0.003)LDVIDGPISQR;GS(0.997)GFS(0.003)LDVIDGPISQR 172.91 1.6243e-05 10734500.0 24057.9 34232.6 31834.2 32515.0 35467.0 24559.7 37010.6 29447.699999999997 29100.5 23652.8 True False 28130.4273048158 37630.98629262817 32593.248059875783 30693.289965052285 28517.495951989797 23271.746097119107 33504.688034460174 28674.729077417232 29526.039759762814 27940.865404538228 1.0067843961714509 1.3468081874985893 1.1665081803293718 1.0985089230653178 1.020637533558925 0.8328928170327626 1.1991285004729402 1.0262648870124047 1.0567331874755432 1.0 14.770089085175155 -5.930901462050109 2.795387248957786 1.024546877531497 1.1917578931889827 0.2613329746539188 0.11296896324991453 0.34023023104904954 5.390572846847252 0.03361043301382998 0.0528024436988501 1.172461357490606e-06 5.930901462050109 0.16721101565748575 GS(ph)GFSLDVIDGPISQR ddPTM_PC-9_Lapatinib_30min_R1 3 GSGFSLDVIDGPISQR 16 0 O43166-3;O43166-2;O43166 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 GS(1)GFSLDVIDGPISQR;GS(0.998)GFS(0.002)LDVIDGPISQR;GS(1)GFSLDVIDGPISQR 197.73 5.7992e-12 10594400.0 14099.5 24300.7 24588.0 26465.5 27202.8 23648.0 24973.300000000003 25766.4 23503.1 20651.7 True False 13898.438544468374 24244.43322218055 22566.46955242474 28411.861156319912 25602.78478676253 22636.63016618046 26266.295278704652 26963.601008867794 20855.933379384885 24221.31882833948 0.5738101481165795 1.0009542995575462 0.931677986337452 1.1730104936762322 1.0570351254699932 0.9345746334710354 1.0844287821343777 1.1132177070936278 0.861056886587983 1.0 14.563989800126901 -4.751997662722674 4.399848312759201 1.0262303890567313 0.5288734015380225 0.691596519290463 0.08880623415572898 0.1274945588139822 5.158090264070542 0.02194150336896764 0.20512107129523893 1.7701184846799182e-05 4.751997662722674 -0.4973569875187087 GS(ph)GGGGGGGGQGSTNYGK ddPTM_PC-9_AZD4547_30min_R2 3 GSGGGGGGGGQGSTNYGK 18 0 Q99729-3;Q99729-4 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 1 GS(1)GGGGGGGGQGSTNYGK;GS(1)GGGGGGGGQGSTNYGK;GS(1)GGGGGGGGQGSTNYGK 230.67 1.9499e-35 37979700.0 18590.7 19541.9 29172.9 31366.4 30281.7 28228.699999999997 24072.6 37721.0 24991.0 28317.9 True False 24502.1558894181 25858.437012317234 28786.048284765755 24135.361086049197 26077.608655190037 26463.55492652304 26215.014765194526 31892.08619234797 26311.973239862327 27326.498940297923 0.896644533313603 0.946276984432288 1.0534115016949888 0.8832218550491732 0.9542974646025303 0.9684209815659073 0.9593257746800374 1.1670754552943208 0.9628739231230427 1.0 14.738013013760376 -7.569406841601381 24.999983689780656 1.0516251726848505 0.952990382114244 0.29229741516583974 0.06502499165251656 141.18570322088607 75858.8240585382 0.029087068818307683 0.016793434176710587 2.6952134074773708e-08 7.569406841601381 -0.09863479057060642 GS(ph)GGGGGGGGQGSTNYGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GSGGGGGGGGQGSTNYGK 18 0 Q99729-3;Q99729-4 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 1 GS(1)GGGGGGGGQGSTNYGK;GS(1)GGGGGGGGQGSTNYGK;GS(1)GGGGGGGGQGSTNYGK;GS(1)GGGGGGGGQGSTNYGK 235.26 2.8594000000000004e-43 47109100.0 34614.5 35979.1 45401.9 40632.6 51531.0 41391.6 45435.0 46614.6 43218.6 32884.8 True False 40474.05118246174 39550.867270411756 46484.45348366457 38356.087154666595 41433.870468378685 39220.951630252646 41131.06787908592 45391.01614225127 43850.590263441714 38846.553924066444 1.0418955375443746 1.018130651890565 1.1966171716165086 0.9873742528009417 1.0666035023175977 1.0096378614926318 1.0588086644566985 1.1684695695524838 1.1288154503783447 1.0 15.245499002450899 -7.565364973195883 24.724883567750044 1.111913482945941 1.0540811868509725 0.0783681391658343 0.06659441843775919 259.4981624963392 151012.0158787224 0.030454878433883052 0.017583172122047325 2.720414160515609e-08 7.565364973195883 -0.05783229609496843 GS(ph)GGGGGGGGQGSTNYGK ddPTM_PC-9_Lapatinib_30min_R1 2 GSGGGGGGGGQGSTNYGK 18 0 Q99729-3;Q99729-4 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 1 GS(1)GGGGGGGGQGSTNYGK;GS(1)GGGGGGGGQGSTNYGK 210.47 1.2626e-20 9062500.0 13611.5 22728.0 23825.0 20074.5 23583.0 19553.8 21753.0 21472.9 24606.0 17982.4 True False 13417.397513956605 22675.374712404155 21866.200467159575 21550.845696568893 22195.89430596191 18717.52955613412 22879.263901753562 22470.609324675454 21834.613167333035 21090.63387995815 0.6361780110699655 1.07513955443283 1.0367730335472953 1.0218206725900292 1.05240527298964 0.8874806543354239 1.0848068404191065 1.0654307240157754 1.035275340305531 1.0 14.364314835597574 -4.757333597298063 24.999951246120762 1.0289410590344432 0.6361774394017022 0.8313760931084422 0.05304543002359165 47.147023122927905 287037.8140317583 0.01324461185661817 0.09946280038419332 1.7485030842005398e-05 4.757333597298063 -0.392763619632741 GS(ph)GGLFSPSTAHVPDGALGQR ddPTM_PC-9_AZD4547_30min_R2 5 GSGGLFSPSTAHVPDGALGQR 21 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 GS(0.997)GGLFS(0.002)PSTAHVPDGALGQR;GS(1)GGLFSPSTAHVPDGALGQR;GS(0.998)GGLFS(0.002)PSTAHVPDGALGQR;GS(0.972)GGLFS(0.018)PS(0.005)T(0.005)AHVPDGALGQR;GS(1)GGLFSPSTAHVPDGALGQR 138.0 1.315e-06 196375000.0 63539.3 71259.7 148807.8 181329.5 154613.2 171445.6 105228.3 190480.5 125841.9 134327.4 True False 83743.47570045794 94293.00446561597 146834.51134271082 139526.78528784798 133147.8259980985 160725.07952936884 114593.41484577148 161046.11553144263 132493.6459226692 129624.63861207858 0.6460459724101759 0.7274311849601534 1.1327669871631072 1.0763909298555738 1.0271799206057084 1.2399269247751816 0.8840403805383765 1.2424035835764031 1.0221331942855136 1.0 16.98398044130915 -5.201651491485182 4.867941923802387 1.083915247829888 0.6710685350173948 0.6947833955090386 0.10395126826955355 0.10355967491260985 5.094211596839558 0.024702030111251893 0.06871866002204417 6.285625594014478e-06 5.201651491485182 -0.4128467128124931 GS(ph)GGLFSPSTAHVPDGALGQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 GSGGLFSPSTAHVPDGALGQR 21 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 GS(0.999)GGLFS(0.001)PSTAHVPDGALGQR;GS(0.987)GGLFS(0.011)PST(0.001)AHVPDGALGQR;GS(0.96)GGLFS(0.038)PS(0.001)T(0.001)AHVPDGALGQR;GS(0.976)GGLFS(0.022)PS(0.001)T(0.001)AHVPDGALGQR;GS(1)GGLFSPSTAHVPDGALGQR;GS(0.969)GGLFS(0.031)PSTAHVPDGALGQR 154.52 1.3175999999999999e-05 138189800.0 70004.2 92753.0 159263.0 146257.09999999998 165376.0 126606.3 151084.0 108024.79999999999 107888.5 77618.5 True False 81854.5284140255 101960.90485677784 163060.43392829114 138062.7888589156 132971.75996154934 119966.84275034683 136772.22976656383 105189.26346173647 109466.16520751068 91690.11962229214 0.8927300864173442 1.1120162704203584 1.7783860965609113 1.5057542669553798 1.450229975806691 1.308394440366505 1.4916790416457382 1.1472257195764672 1.1938708953423236 1.0 16.484478659281365 -8.200154214361772 1.508547164610117 1.029910434496708 1.374472535394699 0.18696529032697196 0.23075816408278935 0.6741945476930753 2.844641083949387 0.2292409127856139 0.07113613123808045 6.307333365441137e-09 8.200154214361772 0.3445621008979909 GS(ph)GGLFSPSTAHVPDGALGQR ddPTM_PC-9_Lapatinib_30min_R1 4 GSGGLFSPSTAHVPDGALGQR 21 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 GS(1)GGLFSPSTAHVPDGALGQR;GS(1)GGLFSPSTAHVPDGALGQR;GS(0.931)GGLFS(0.069)PSTAHVPDGALGQR;GS(0.999)GGLFS(0.001)PSTAHVPDGALGQR 141.69 5.1871000000000005e-05 131207000.0 128832.6 138184.0 198551.0 127285.0 191056.0 218589.0 168825.0 182470.0 214516.0 126530.0 True False 126995.4234989946 137864.04343799944 182226.90320902396 136645.9635103129 179818.46171054832 209240.45802584657 177565.93243293063 190948.2223394847 190354.949126376 148400.54190937255 0.8557611843260656 0.9289995957170581 1.2279396076620057 0.9207915399241728 1.2117102767748822 1.4099709834862237 1.1965315634855918 1.2867083898931837 1.2827106065598117 1.0 17.179136834647124 -6.360284967738659 5.494020446879884 1.256203867053006 0.9976992527987528 0.44632343065318436 0.13376919463820297 0.20707182895569123 9.295054923653604 0.041224767822840465 0.04688494085211644 4.3622950088500726e-07 6.360284967738659 -0.2585046142542532 GS(ph)GLAGPK ddPTM_PC-9_AZD4547_30min_R2 1 GSGLAGPK 8 0 Q9Y6W5 Q9Y6W5 WASF2 Wiskott-Aldrich syndrome protein family member 2 1 GS(1)GLAGPK 77.66199999999999 0.023224 25854000.0 68560.0 68430.0 89179.0 97114.0 113600.0 138640.0 73106.0 104110.0 101220.0 108780.0 True False 90360.65386341044 90548.65927841554 87996.42819147644 74725.86769634334 97828.60087873491 129970.81888337615 79612.29237491211 88022.19170979965 106570.28255527445 104971.64531005522 0.8608101130215857 0.8626011244366186 0.8382875959651866 0.7118671663726448 0.9319526295865721 1.2381516789555957 0.7584171148290658 0.8385330290842646 1.0152292291932485 1.0 16.679640157614443 -6.50030356861264 24.736510261624158 0.9621137335734314 0.8228378845281692 0.2520870434801039 0.12360998123766295 1095.9579552189714 1200885.5463373666 0.04017362490584793 0.045200969045014354 3.1600680239540237e-07 6.50030356861264 -0.13927584904526225 GS(ph)GLAGPK ddPTM_PC-9_Lapatinib_30min_R1 2 GSGLAGPK 8 0 Q9Y6W5 Q9Y6W5 WASF2 Wiskott-Aldrich syndrome protein family member 2 1 GS(1)GLAGPK;GS(1)GLAGPK 79.986 0.019938 48632000.0 144049.0 229623.0 225285.0 206966.0 335750.0 364120.0 387240.0 363210.0 429750.0 269407.0 True False 141994.83484464884 229091.32205149546 206762.93692524865 222186.97005833668 316001.84510989726 348547.43640517746 407289.3924201284 380086.06256329385 381347.02953187673 315973.64098773757 0.4493882287167094 0.7250330164736308 0.6543676753507195 0.7031819786099164 1.0000892609968082 1.1030902302977357 1.2889980035895925 1.2029043352323316 1.206895069917165 1.0 18.269444685996127 -6.3619622961516 1.5054159762977282 1.1925331320908794 0.6071176619955142 0.8755721874894523 0.09465774979137681 0.12308119750815334 0.5601253072969018 0.03520923272271376 0.044389970819986906 4.34547948387436e-07 6.3619622961516 -0.5854154700953652 GS(ph)HSFDER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSHSFDER 8 0 P31629 P31629 HIVEP2 Transcription factor HIVEP2 1 GS(0.79)HS(0.21)FDER 61.161 0.037949000000000004 3106200.0 4287.1 6344.0 9352.7 3018.8 8501.8 10860.0 3139.2 8360.8 3923.5 3732.8 True False 5012.821355915348 6973.7903939646185 9575.703838312274 2849.6664230816505 6835.933320681954 10290.482482062627 2841.832250160152 8141.3378589998565 3980.87376496725 4409.527091171458 1.1368160921273796 1.581527962018241 2.1715942867171143 0.6462521635907658 1.5502645021432184 2.3336929945766145 0.6444755166262457 1.8463063477487303 0.9027892748266731 1.0 12.106408223935635 -8.284873175890283 24.277641335676318 0.9513943113056387 1.488686575818521 0.13863961911368838 0.5358757355481817 1253.1480856049811 1298255.915184185 0.4960685873364003 0.12844788219585723 5.189515627538538e-09 8.284873175890283 0.5372922645128824 GS(ph)HSLDDLLDRPGNSIAPSEYWDGQSR ddPTM_PC-9_AZD4547_30min_R2 1 GSHSLDDLLDRPGNSIAPSEYWDGQSR 27 1 Q6UXY1;B0QYF0 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 GS(0.527)HS(0.468)LDDLLDRPGNS(0.004)IAPSEYWDGQSR 53.998000000000005 0.0021620999999999997 13394000.0 4654.3 1917.6 7498.0 11123.0 7819.7 5332.3 5637.7 7242.5 6683.4 7736.8 True False 6134.270584545961 2537.426699288173 7398.571620893835 8558.764198636924 6734.0696328472095 4998.870438054137 6139.444378327946 6123.338041093295 7036.670879568476 7465.936986898644 0.8216343903398174 0.3398671464467077 0.9909769709919836 1.146375091787674 0.9019724710594627 0.6695570089630064 0.822327376871992 0.8201700673121988 0.9425033846276158 1.0 12.866107616893684 -5.279261239086101 24.987284182226716 0.9015017614335511 0.5807507288011478 0.399616339564151 0.16188999857853753 736.8851406236204 1033155.1405191716 0.043804309100778656 0.09149419129879562 5.257009488820134e-06 5.279261239086101 -0.32075103263240334 GS(ph)HSLDDLLDRPGNSIAPSEYWDGQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSHSLDDLLDRPGNSIAPSEYWDGQSR 27 1 Q6UXY1;B0QYF0 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 GS(0.498)HS(0.498)LDDLLDRPGNS(0.004)IAPSEYWDGQSR;GS(0.749)HS(0.237)LDDLLDRPGNS(0.008)IAPS(0.003)EY(0.003)WDGQSR 47.854 0.011618 16081600.0 5848.0 8583.0 13398.0 16307.599999999999 13833.5 13420.699999999999 11500.8 12860.2 12806.099999999999 10104.0 True False 6837.950896735076 9435.063516929118 13717.459132197944 15393.938041952542 11122.924979610647 12716.894866207918 10411.360965418547 12522.633376508216 12993.364985739023 11935.775216780015 0.5728954150478539 0.7904860258816495 1.1492725761886946 1.2897308940864467 0.9318979938540887 1.0654435623360063 0.8722819235722238 1.049167996972929 1.0886067096397882 1.0 13.54300465062635 -5.02298000204701 3.476901174664637 1.0541562824291624 0.5923980186149334 0.6721448561770031 0.10930608724799326 0.14151574498476002 3.483213582439635 0.0301974282080366 0.12511824808644928 9.484621361204108e-06 5.02298000204701 -0.461758263814229 GS(ph)HSLDDLLDRPGNSIAPSEYWDGQSR ddPTM_PC-9_Lapatinib_30min_R1 1 GSHSLDDLLDRPGNSIAPSEYWDGQSR 27 1 Q6UXY1;B0QYF0 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 GS(0.559)HS(0.439)LDDLLDRPGNS(0.001)IAPSEYWDGQSR 52.143 0.005617100000000001 9467900.0 3155.6 2966.0 3343.8 3869.1 3932.4 3791.6 2424.3 3183.3 2523.1 3344.0 True False 3110.6005653338348 2959.1324092304967 3068.885671441269 4153.646520939234 3701.1039633958612 3629.442106651297 2549.818391808999 3331.207739207993 2238.9219085791256 3922.005944400086 0.7931146993224752 0.7544946262653176 0.7824785874746268 1.0590617606966886 0.9436762758303229 0.9254045399481056 0.6501311899972201 0.849363256056344 0.5708614266064285 1.0 11.937376006818877 -7.243692611512152 24.79510963208658 0.7550358935148974 0.8779273971868465 0.1306089688495745 0.1359250820273264 1422.8170242579195 1987908.4076114136 0.0524005992786823 0.04049328944059288 5.7056797064575685e-08 7.243692611512152 0.12289150367194912 GS(ph)IGLLLGK ddPTM_PC-9_AZD4547_30min_R2 2 GSIGLLLGK 9 0 Q8IY63-2;Q8IY63 Q8IY63-2 AMOTL1 Angiomotin-like protein 1 1 GS(1)IGLLLGK;GS(1)IGLLLGK 87.29799999999999 0.010998 4638500.0 14363.9 21033.0 22893.0 26573.0 25839.0 36826.0 32476.0 35794.0 33282.0 30472.0 True False 18931.32141231975 27831.505927267477 22589.42386197953 20447.005398757425 22251.700863605904 34523.26439843628 35366.30108565165 30262.859764293207 35041.21857345034 29405.184554954933 0.6438089642640832 0.9464829535503704 0.7682122797006247 0.6953537516673057 0.7567271282389 1.174053654855192 1.202723316344302 1.0291674826163861 1.1916680375857631 1.0 14.843782924825105 -6.758003286156094 24.99958062173666 1.126545542262857 0.768989071791601 0.7788405089683623 0.09515491186092441 40.60666189437094 295437.29133275116 0.03150640607427636 0.03029534596675077 1.7458089429382435e-07 6.758003286156094 -0.35755647047125594 GS(ph)IGLLLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSIGLLLGK 9 0 Q8IY63-2;Q8IY63 Q8IY63-2 AMOTL1 Angiomotin-like protein 1 1 GS(1)IGLLLGK;GS(1)IGLLLGK 99.568 0.0040992 4778200.0 20341.3 28154.0 42836.0 41305.0 42007.0 29454.0 35843.0 35083.0 31934.0 24921.0 True False 23784.680331011838 30948.943056696044 43857.372696434635 38990.814762616814 33776.02989977263 27909.38038919638 32447.69155915213 34162.10842351114 32400.974336807474 29438.980025472534 0.8079315353463936 1.051291282167962 1.4897721544186098 1.3244621494657562 1.1473233743338729 0.9480416904745802 1.1022016228509364 1.1604379089884176 1.1006147056987718 1.0 14.84544006664804 -6.533103232215704 24.681555278243295 1.0717717866249918 1.1895762824698224 0.07352517201913067 0.17411694609848685 516.7627100983241 1247436.7407314435 0.06240097429953703 0.06246827540702202 2.930196651903079e-07 6.533103232215704 0.11780449584483055 GS(ph)IGLLLGK ddPTM_PC-9_Lapatinib_30min_R1 2 GSIGLLLGK 9 0 Q8IY63-2;Q8IY63 Q8IY63-2 AMOTL1 Angiomotin-like protein 1 1 GS(1)IGLLLGK;GS(1)IGLLLGK 101.38 0.0035168 4318100.0 21838.0 28867.0 37209.0 32779.0 30691.0 25966.0 27804.0 23455.0 29421.0 18567.199999999997 True False 21526.58611540128 28800.16023508318 34149.81965089363 35189.67700753852 28885.815720827577 24855.494709702394 29243.55507398315 24544.80492668723 26107.297163135216 21776.515780761132 0.9885229727346622 1.3225329765805427 1.5681948386373143 1.6159461578618328 1.3264663645755161 1.1413898788924464 1.3428941235777907 1.1271226845376152 1.1988739349294892 1.0 14.41048552240471 -6.621875067513366 5.154379965290978 1.1825345146367339 1.3937714441349538 0.24140009385896144 0.1771190405858092 0.3327058431282853 14.163607921892565 0.06280764378711688 0.06271765438159223 2.3884982778568294e-07 6.621875067513366 0.21123692949821993 GS(ph)ISSGLEFVSHNPPSEAATPPVAR ddPTM_PC-9_AZD4547_30min_R2 1 GSISSGLEFVSHNPPSEAATPPVAR 25 0 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;F8WB06;F8VRK6 Q99700;F8WB06 ATXN2 Ataxin-2 1 GS(0.515)IS(0.224)S(0.261)GLEFVSHNPPSEAATPPVAR 62.519 0.013262999999999999 0.0 5884.1 5689.1 9038.0 10854.0 11476.0 9119.3 8424.0 10464.0 5898.8 6250.0 True False 7755.121403116882 7527.990318585911 8918.15021467571 8351.777992628346 9882.75549017924 8549.068729393908 9173.719680549622 8847.029238798796 6210.598525361125 6031.189402351945 1.2858361569763779 1.2481767386794829 1.4786718870407145 1.3847646683706294 1.6386080474152118 1.4174764145294594 1.521046524748867 1.4668796896593523 1.0297468892187696 1.0 12.558226826698577 -8.265744706359103 23.21067600648585 1.01487318618838 1.43377083434023 0.7110088089655686 0.10589004887154935 79.3888227208353 427974.02318519924 0.09614355620177352 0.028433441141550768 5.423195913375631e-09 8.265744706359103 0.41889764815185004 GS(ph)ISSTSEVHSPPNVGLR ddPTM_PC-9_AZD4547_30min_R2 2 GSISSTSEVHSPPNVGLR 18 0 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 GS(0.991)IS(0.004)S(0.004)T(0.001)SEVHSPPNVGLR;GS(0.971)IS(0.009)S(0.019)T(0.001)SEVHSPPNVGLR 159.04 8.688300000000001e-06 17054900.0 11776.400000000001 8698.5 26247.0 28772.0 21766.1 26048.3 16288.7 30955.0 20903.8 18606.6 True False 15521.050235663166 11510.120016561408 25898.947630514856 22139.05992296876 18744.252725234444 24419.495683207166 17738.362744606915 26171.616025135365 22008.732192046482 17955.188597408258 0.8644325929221124 0.6410470129076136 1.4424213641650772 1.2330173978882308 1.043946301290318 1.36002446037977 0.9879240559560237 1.4576074143221813 1.2257588981952177 1.0 14.132113186387533 -5.253643099941928 24.997495163940982 1.226236405372637 0.7527397672186595 0.5497106820141662 0.16863272157334758 400.86242238183934 1285292.1511943622 0.04076690427541184 0.10373475353194064 5.576438283400919e-06 5.253643099941928 -0.47349663815397736 GS(ph)KSPDLLMYQGPPDTAEIIK ddPTM_PC-9_AZD4547_30min_R2 1 GSKSPDLLMYQGPPDTAEIIK 21 1 P82909 P82909 MRPS36 28S ribosomal protein S36, mitochondrial 1 GS(0.623)KS(0.377)PDLLMYQGPPDTAEIIK 94.31299999999999 0.00018019 7399900.0 28843.0 20100.0 31179.0 45097.0 43373.0 32935.0 31540.0 32124.0 28861.0 35350.0 True False 38014.47402833062 26596.931923076903 30765.546088003313 34700.58339170451 37351.407622476865 30875.569243537142 34346.998898923914 27159.973936083006 30386.533539100736 34112.40725970257 1.114388490349598 0.7796849902907967 0.9018872767840999 1.017242293325243 1.0949508001037664 0.9051125887562573 1.0068770180138669 0.7961904807629169 0.8907765818977174 1.0 15.058008946845888 -10.728291987018963 5.719264891844226 1.00000165964284 0.9418610884968169 0.02186185472333002 0.10779172453380367 2.2974215526540607e-06 3.1921007997487265e-07 0.10511677295334539 0.025493834547315065 1.86942485677475e-11 10.728291987018963 -0.05814057114602311 GS(ph)KSPDLLMYQGPPDTAEIIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSKSPDLLMYQGPPDTAEIIK 21 1 P82909 P82909 MRPS36 28S ribosomal protein S36, mitochondrial 1 GS(0.59)KS(0.41)PDLLMYQGPPDTAEIIK;GS(0.577)KS(0.422)PDLLMY(0.001)QGPPDTAEIIK 92.41 0.00061907 19288400.0 58987.0 53714.0 57881.0 66965.0 67132.0 63236.0 63802.0 73075.0 58757.0 51574.0 True False 68972.33405364434 59046.37093654085 59261.102554914905 63213.16815345923 53977.96651109421 59919.792839384216 57758.212673521295 71156.8586793626 59616.20996767701 60923.95794044067 1.1321052732829961 0.9691814670718644 0.9727060512524256 1.0375748767874946 0.8859891631443763 0.9835177303805815 0.9480377609410372 1.1679618508850924 0.9785347502530595 1.0 15.894722049469907 GS(ph)LASLDSLR ddPTM_PC-9_AZD4547_30min_R2 3 GSLASLDSLR 10 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;E9PKY0 O60716 CTNND1 Catenin delta-1 1 GS(1)LASLDSLR;GS(0.997)LAS(0.003)LDSLR;GS(0.995)LAS(0.005)LDSLR 145.23 0.00013692 291007000.0 82834.0 119041.0 122759.0 118127.0 114847.0 108449.0 126643.0 133660.0 120007.0 97145.0 True False 109173.48894576612 157518.67527636787 121131.13545069423 90894.64519395701 98902.47645352186 101667.66688605899 137913.98166000078 113005.91820124688 126350.32502085385 93743.9831186368 1.1645919590124805 1.6803070451681323 1.2921483749778147 0.969605111390735 1.055027460571595 1.084524718321329 1.471176891272745 1.205473828205415 1.3478233036135494 1.0 16.516438474808268 -5.519394591173289 24.774013849809013 1.172263462823646 1.4383940752306503 0.23908581897703096 0.18626604177474745 163.31914665806957 1161274.7584226525 0.050725664115368524 0.09033625096056849 3.0241644848513076e-06 5.519394591173289 0.2661306124070044 GS(ph)LASLDSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GSLASLDSLR 10 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;E9PKY0 O60716 CTNND1 Catenin delta-1 1 GS(1)LASLDSLR;GS(1)LASLDSLR;GS(1)LASLDSLR 158.06 0.00012641 258783000.0 60071.0 70754.0 100041.0 72685.0 97334.0 64161.0 73845.0 56635.0 50804.0 65223.0 True False 70239.83384366843 77777.98952310417 102426.35684760542 68612.69509794947 78262.10141796528 60796.28421101474 66849.86700849788 55148.39125974273 51546.912388274766 77047.41359501595 0.911644279363741 1.0094821603218032 1.329393837747607 0.8905256113929811 1.0157654587775533 0.7890762502499828 0.8676458285787579 0.7157721289596952 0.6690284590112345 1.0 16.23345890726585 -6.633517404575601 1.5470101692660367 0.78422084568301 1.0613468995849538 0.3749931786947629 0.1406904528143939 0.38141711093458347 1.8869825540556024 0.05889638218155244 0.059341785921059216 2.3253192956346669e-07 6.633517404575601 0.2771260539019438 GS(ph)LASLDSLR ddPTM_PC-9_Lapatinib_30min_R1 2 GSLASLDSLR 10 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;E9PKY0 O60716 CTNND1 Catenin delta-1 1 GS(1)LASLDSLR;GS(1)LASLDSLR 160.72 0.00012641 256730000.0 48125.0 67466.0 75156.0 54546.0 67743.0 69234.0 62700.0 49882.0 79956.0 50310.0 True False 47438.72867495586 67309.78662209882 68976.96379054966 58557.49480012188 63758.48992786233 66273.02321233667 65946.29920654379 52199.69982319387 70950.51330599355 59006.016466138804 0.803964265274187 1.140727516502071 1.1689818754352412 0.9923987129977786 1.0805421844474246 1.1231570470507548 1.1176199166806615 0.8846504636209291 1.2024284565406853 1.0 15.848574443910858 -4.7533540447187095 24.988753868405876 1.0780896494313403 0.8039637600509076 0.4531870159504092 0.09061149899109894 272.503330708555 842139.586087578 0.021734946954464533 0.2361689155588161 1.76459870138212e-05 4.7533540447187095 -0.2741258893804327 GS(ph)LDESSLGFGYPK ddPTM_PC-9_AZD4547_30min_R2 2 GSLDESSLGFGYPK 14 0 Q2KJU6;Q9BUZ4 Q2KJU6 TRAF4 TNF receptor-associated factor 4 1 GS(1)LDESSLGFGYPK;GS(1)LDESSLGFGYPK 213.52 2.9534000000000002e-15 21980200.0 50159.0 49031.0 62982.0 75859.0 64780.0 66420.0 59008.0 78776.0 55362.0 52708.0 True False 66108.51862798732 64879.31189653649 62146.81752829226 58370.87955986679 55786.415184194106 62266.74690012867 64259.59768635712 66602.97929239435 58288.32229623693 50862.70896306657 1.2997443505415986 1.275577200255848 1.221854258164258 1.1476164119031136 1.0968038533830913 1.2242121619071258 1.2633931419779185 1.3094658277198215 1.1459932725675779 1.0 15.634320681992413 -8.535692780697294 20.795531527284833 0.9999999966569664 1.2250287055850702 0.5597931514972561 0.06259716870825861 160.47482596254514 260431.60103790913 0.06769461647720453 0.01747867481532069 2.9127768836939323e-09 8.535692780697294 0.22502870892810378 GS(ph)LDESSLGFGYPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GSLDESSLGFGYPK 14 0 Q2KJU6;Q9BUZ4 Q2KJU6 TRAF4 TNF receptor-associated factor 4 1 GS(0.985)LDES(0.003)S(0.013)LGFGYPK;GS(0.998)LDES(0.002)S(0.001)LGFGYPK;GS(1)LDESSLGFGYPK 171.26 4.6284e-05 15079500.0 110734.0 131163.0 127065.0 155818.0 179949.0 139879.0 158229.0 143580.0 143091.0 108718.0 True False 129479.07910380709 144183.99581393116 130094.71149669585 147088.02262877207 144689.28522470492 132543.49899709394 143240.40364124315 139811.17713558485 145183.43517342358 128427.71278878559 1.008186444282089 1.1226860050918965 1.0129800544735375 1.1452981559414326 1.1266204317028006 1.0320474928575365 1.1153387421671113 1.088637133680958 1.1304681210993357 1.0 16.970597022605567 -5.7543546975360025 24.999898274413784 1.0949114184426434 1.0554243714699179 0.12035369864258516 0.05175165133096318 375.82611344670227 1326172.894998141 0.013403078530524172 0.02258962143655494 1.7605375906054919e-06 5.7543546975360025 -0.03948704697272554 GS(ph)LDESSLGFGYPK ddPTM_PC-9_Lapatinib_30min_R1 2 GSLDESSLGFGYPK 14 0 Q2KJU6;Q9BUZ4 Q2KJU6 TRAF4 TNF receptor-associated factor 4 1 GS(1)LDESSLGFGYPK;GS(1)LDESSLGFGYPK 234.85 8.1725e-27 20195800.0 57703.0 76835.0 79210.0 63495.0 81262.0 79638.0 84683.0 72379.0 81099.0 73211.0 True False 56880.144638565755 76657.09327822819 72697.65955944214 68164.63411311072 76482.32892723907 76232.06838524518 89067.4713828988 75741.99257253023 71964.77660967005 85865.42380247447 0.6624336330000922 0.8927585736322783 0.8466464886573719 0.7938542791090999 0.8907232450535578 0.8878086779215119 1.0372914665603974 0.8821011906581598 0.8381112375945226 1.0 16.389789684944 -3.0469599693545453 0.3851252366025917 0.9334886645244117 2.731484291493586e-26 0.4835681976740418 0.07064593950278798 21.554456836888658 0.8701523453955272 0.05658794602422153 12.259080560417411 0.0008975115178856874 3.0469599693545453 -0.9334886645244117 GS(ph)LDWPSEER ddPTM_PC-9_AZD4547_30min_R2 2 GSLDWPSEER 10 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 GS(1)LDWPSEER;GS(1)LDWPSEER 142.19 0.0001234 4983300.0 57818.0 52032.0 52402.0 54229.0 60198.0 51695.0 43624.0 68625.0 49832.0 51307.0 True False 76202.92131089077 68850.3264587829 51707.11524114146 41727.34187969806 51840.54679311696 48462.50347790045 47506.45148911403 58020.58309561996 52466.017785955686 49510.75754663539 1.5391184681251016 1.3906134721112096 1.0443612217493798 0.8427934442407604 1.0470562229690605 0.9788277513680221 0.9595177663029402 1.171878314343483 1.059689255138879 1.0 15.595454403186283 -5.184675647589447 3.1042505696293534 1.0084446565620784 1.5132900211861853 0.8418984901993073 0.07956668839423137 0.09893500776417723 1.8226640649825805 0.022538598800855267 0.07488466275451712 6.536185247622533e-06 5.184675647589447 0.5048453646241069 GS(ph)LDWPSEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSLDWPSEER 10 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 GS(1)LDWPSEER 119.03 0.0008238999999999999 2142100.0 23258.0 28145.0 27465.0 23291.0 32704.0 20728.0 20125.0 21652.0 17811.0 14742.0 True False 27195.120033560946 30939.04959617497 28119.86976159255 21986.080780440818 26295.88596762835 19640.987190441447 18218.614307617583 21083.65794219032 18071.45217989846 17414.607902392207 1.5616268931225958 1.7766147690253158 1.6147288482866033 1.262507941819387 1.509990125245148 1.1278455019216027 1.04616850461014 1.2106880648914353 1.0377180055495838 1.0 14.088010369922118 -6.255520242823972 0.6955088588847348 1.049688750260893 1.7260147413468636 0.798120281770785 0.11877565916217046 0.3512033594222709 0.3631548185324032 0.07383263138441495 0.13629182565081152 5.552387363809884e-07 6.255520242823972 0.6763259910859707 GS(ph)LDWPSEER ddPTM_PC-9_Lapatinib_30min_R1 2 GSLDWPSEER 10 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 GS(1)LDWPSEER;GS(1)LDWPSEER 140.63 0.0001234 3960500.0 47633.0 53657.0 49351.0 48471.0 46799.0 39616.0 37162.0 36252.0 46210.0 52121.0 True False 46953.744685177604 53532.76051317624 45293.55128036906 52035.71903451599 44046.374830374036 37921.71602940649 39086.066524937516 37936.40026443259 41005.34318712749 61130.04540313302 0.7680960217767341 0.8757192990802619 0.7409376351951422 0.8512298443647004 0.7205356145231422 0.6203449675086113 0.6393920741785395 0.6205851805647159 0.6707886918242971 1.0 15.899594018185834 -6.44152230657961 5.192099547281034 0.6808192650468247 0.8079714415546548 0.12876087488997723 0.11118533448124529 0.32716627886526645 15.17888938367618 0.03287766979949769 0.03699883991309368 3.6180760680426353e-07 6.44152230657961 0.12715217650783017 GS(ph)LGSQGAKDEPEEELQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSLGSQGAKDEPEEELQK 18 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 GS(0.578)LGS(0.422)QGAKDEPEEELQK 55.588 0.018544 14370000.0 15265.0 16918.0 16606.0 21286.0 20326.0 14040.0 18508.0 16092.0 13560.0 12568.0 True False 17849.063002507006 18597.50723283312 17001.95001860571 20093.4144301431 16343.266211411874 13303.717683992567 16754.788253683786 15669.60205088337 13758.289347000347 14846.478911766733 1.2022421685697167 1.252654406702014 1.1451839941072246 1.3534127889554912 1.1008176624599417 0.8960857158830142 1.1285361568394916 1.0554423135619222 0.9267038621592673 1.0 13.857833192132993 -6.516033553166489 24.175030993642018 1.0111769776457717 1.232034329809395 0.6749490140139117 0.07734836721419129 123.8992635193512 437575.1457120577 0.024295305757948558 0.02522515995608295 3.047659521341177e-07 6.516033553166489 0.22085735216362323 GS(ph)LPSGTTIEWLEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSLPSGTTIEWLEPK 15 0 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 GS(0.911)LPS(0.03)GT(0.03)T(0.03)IEWLEPK 83.869 0.0063295 2295500.0 19792.0 24987.0 26873.0 23627.0 33334.0 23753.0 35122.0 26558.0 22463.0 22090.0 True False 23142.39469018138 27467.544226669906 27513.75423642002 22303.255789767507 26802.441990121184 22507.350865233286 31794.9898987401 25860.880640527004 22791.478879179132 26094.74213565621 0.8868604475902943 1.052608379261885 1.054379234459836 0.8547030537347995 1.027120400377437 0.8625243640357317 1.2184443032029426 0.9910379840538965 0.8734126882992472 1.0 14.671471525081435 GS(ph)LSLSFEREPSTSDLGTTDVQK ddPTM_PC-9_AZD4547_30min_R2 1 GSLSLSFEREPSTSDLGTTDVQK 23 1 P57078-2;P57078 P57078-2 RIPK4 Receptor-interacting serine/threonine-protein kinase 4 1 GS(0.391)LS(0.298)LS(0.26)FEREPS(0.017)T(0.017)S(0.017)DLGT(0.001)TDVQK 62.361999999999995 0.0016394000000000003 4704200.0 9990.0 11673.0 13334.0 17249.0 15964.0 10439.0 8822.6 12398.0 9783.5 10533.0 True False 13166.612195091462 15446.068972043613 13157.182447719168 13272.50954439345 13747.674158698273 9786.247679771797 9607.794308359107 10482.173977697577 10300.635836588886 10164.242875995682 1.2953854365470059 1.5196477652577274 1.2944576992342185 1.3058040531221844 1.35255270130994 0.9628112786328066 0.9452543023198798 1.0312793688207447 1.0134189001834377 1.0 13.311215133863676 -6.758482704965834 24.999563595370898 0.9896765448880828 1.3568585279661527 0.8871651004289625 0.064725883549908 24.35630337338306 205940.0657912377 0.022328899867877252 0.02140831120072974 1.7438828032299052e-07 6.758482704965834 0.36718198307806993 GS(ph)LSNAGDPEIVK ddPTM_PC-9_AZD4547_30min_R2 2 GSLSNAGDPEIVK 13 0 F5H7V1;O43847;O43847-2 F5H7V1 NRD1 Nardilysin 1 GS(0.971)LS(0.029)NAGDPEIVK;GS(0.644)LS(0.356)NAGDPEIVK 164.15 0.00015673 15859800.0 100488.0 122245.0 113412.0 112299.0 104111.0 119392.0 124206.0 142360.0 109365.0 110794.0 True False 132441.09371975504 161758.30561873325 111908.0827779155 86410.20055225467 89656.9847366723 111926.3993661569 135260.09338109515 120361.53310735813 115145.81062692743 106915.13578306885 1.2387497125615445 1.5129598296254458 1.0467000949704386 0.8082129805042875 0.8385808433951447 1.0468714139152002 1.2651164158416102 1.125767013489765 1.0769832520304576 1.0 16.70610658169013 -5.302856136831962 10.39587155717077 1.0251816636932178 1.3756945261808142 0.5056591102400887 0.1383554156190227 0.5629383465732998 140.17020115116023 0.040627204421143065 0.08501062256972972 4.979019912768413e-06 5.302856136831962 0.3505128624875964 GS(ph)LSNAGDPEIVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GSLSNAGDPEIVK 13 0 F5H7V1;O43847;O43847-2 F5H7V1 NRD1 Nardilysin 1 GS(0.999)LS(0.001)NAGDPEIVK;GS(0.739)LS(0.261)NAGDPEIVK;GS(0.997)LS(0.003)NAGDPEIVK 160.81 6.934e-05 12217800.0 112201.0 157795.0 131206.0 117541.0 126261.0 83286.0 106263.0 75047.0 82050.0 69181.0 True False 131194.41322923594 173459.8447691752 134334.44864152564 110955.5588430636 101521.06342217236 78918.33554337636 96196.99936250255 73077.0957688691 83249.82602665054 81722.9676635052 1.6053554708075422 2.1225348237890374 1.643778395256625 1.3577034953004126 1.2422586492476133 0.9656812252379658 1.1771109409363871 0.8942051158710299 1.018683344557826 1.0 16.318453974169827 -5.949421086417845 1.2999972947474725 1.0161813368362118 1.8864093234236925 0.8414685504100521 0.14657794715892725 0.15613377983710353 0.5353933262567219 0.050822824215908884 0.10027755920809589 1.1235150997064955e-06 5.949421086417845 0.8702279865874807 GS(ph)LSNAGDPEIVK ddPTM_PC-9_Lapatinib_30min_R1 2 GSLSNAGDPEIVK 13 0 F5H7V1;O43847;O43847-2 F5H7V1 NRD1 Nardilysin 1 GS(1)LSNAGDPEIVK;GS(1)LSNAGDPEIVK 145.69 9.9331e-05 14360900.0 78476.0 125856.0 117845.0 109200.0 116910.0 120294.0 124533.0 124096.0 117303.0 98701.0 True False 77356.91784926422 125564.58816456933 108156.2389948549 117230.9322805211 110033.58365390344 115149.30603901013 130980.70939535115 129861.95319472095 104091.10088464874 115761.33633918443 0.6682448587376875 1.0846850264121093 0.9343036493458717 1.012695049900173 0.950521021384044 0.994712999007017 1.1314719882947228 1.1218076544505435 0.8991871049212707 1.0 16.8207939558661 -4.754569779874229 24.999935111797278 1.0166770626798374 0.6682442627700566 0.6637577532811583 0.07389027419899159 147.13747192202166 535417.2963297432 0.01876789894285358 0.18056322067841557 1.7596659083533978e-05 4.754569779874229 -0.3484327999097808 GS(ph)LTLTISGESPK ddPTM_PC-9_AZD4547_30min_R2 2 GSLTLTISGESPK 13 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 GS(0.998)LT(0.001)LTISGESPK;GS(0.999)LT(0.001)LTISGESPK 190.34 1.741e-05 57576000.0 406630.0 338500.0 491120.0 673330.0 616750.0 521830.0 409980.0 515750.0 407100.0 440700.0 True False 535929.8815705744 447913.50527171785 484607.42790789256 518104.1713447984 531124.9083799273 489199.887607559 446467.4257635014 436052.6882559711 428618.47488887823 425271.2271386395 1.260207245095046 1.0532419705076754 1.1395255474217854 1.2182911475830815 1.2489086363860191 1.1503244432948165 1.0498416005415572 1.0253519646505895 1.0078708540259356 1.0 18.698023723313923 -7.299598931395691 2.8514567980628645 1.0155278400550145 1.1780749713979746 0.6638620473823222 0.05571018444130825 0.18730116451266288 3.035978052013056 0.027244212062285816 0.0179272201404793 5.0165029110850843e-08 7.299598931395691 0.16254713134296006 GS(ph)LTLTISGESPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSLTLTISGESPK 13 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 GS(0.837)LT(0.065)LT(0.096)IS(0.002)GESPK;GS(0.983)LT(0.017)LTISGESPK 255.15 9.2816e-44 43400000.0 202875.0 203837.0 194076.0 226500.0 239440.0 210750.0 188605.0 188945.0 180153.0 171734.0 True False 237217.7305361022 224072.590248198 198703.50787732837 213809.93932290768 192523.45083442208 199697.89899582847 170738.96901804753 183985.39395377564 182787.39680900844 202868.01475440414 1.1693205102996767 1.1045239956602548 0.9794718409300875 1.0539361741265623 0.9490084036534523 0.9843735062798664 0.8416258680539037 0.9069216464532954 0.9010163432135634 1.0 17.63018189452034 -4.709207522773239 0.5223775828499132 0.9103710088816924 1.3663842886033553 0.7183307927171431 0.0498168667845824 2.3765915017475585 0.47025353193807146 0.029722783346174966 0.6768998273955319 1.9534058195504266e-05 4.709207522773239 0.45601327972166283 GS(ph)MGNGGRATMSSSNGKSVTWAQNEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSMGNGGRATMSSSNGKSVTWAQNEK 26 2 P41594 P41594 GRM5 Metabotropic glutamate receptor 5 1 GS(0.68)MGNGGRAT(0.087)MS(0.078)S(0.078)S(0.071)NGKS(0.003)VT(0.003)WAQNEK 41.208 0.026108 8668100.0 10929.0 8230.4 14574.0 26213.0 18396.0 28652.0 25189.0 37750.0 24454.0 23165.0 True False 12779.06384241068 9047.459719181334 14921.49943220278 24744.37059369264 14791.435856790946 27149.438681036707 22802.915567432505 36759.1024994312 24811.59348757719 27364.63112596089 0.466992000863741 0.3306260434330499 0.5452841430062881 0.9042464515524786 0.5405311618747997 0.992136110151325 0.8332988470580671 1.343307071461225 0.9067030128551001 1.0 14.740024788759431 -6.121366719494502 0.5774957899165829 1.0884735183331036 0.3085691139648134 0.6455724416550438 0.17428239795364947 0.6772433997121599 0.43970410191756526 0.1210539048063656 0.29352691088370836 7.561940929151035e-07 6.121366719494502 -0.7799044043682901 GS(ph)PATSPHLGR ddPTM_PC-9_AZD4547_30min_R2 2 GSPATSPHLGR 11 0 E9PNR2;Q13671-2;Q13671 E9PNR2 RIN1 Ras and Rab interactor 1 1 GS(0.989)PAT(0.011)SPHLGR;GS(1)PATSPHLGR 104.81 0.0014945 28460000.0 23399.0 27667.0 56879.0 46803.0 53884.0 68814.0 44050.0 80450.0 51409.0 46810.0 True False 30839.395270565088 36609.81669232678 56124.74729592163 36013.29144914176 46403.13670554359 64511.04970167792 47970.36466384268 68018.30105708736 54126.374786446424 45171.19614785513 0.6827225732438222 0.8104681703024844 1.2424897297873883 0.7972622936807439 1.0272727016937089 1.4281457035257434 1.061967996305107 1.5057892386654694 1.1982497565324384 1.0 15.463115496861082 -6.566679735465181 6.39759694244482 1.2581324447491504 0.9043278867862033 0.42213485945362583 0.19567696989779648 0.18522766217563777 18.93568306058051 0.06345086726140846 0.06386814329631466 2.712190962797593e-07 6.566679735465181 -0.3538045579629471 GS(ph)PDGSHPVVVAPYNGGPPR ddPTM_PC-9_Lapatinib_30min_R1 1 GSPDGSHPVVVAPYNGGPPR 20 0 O43474-4;O43474-1;O43474 O43474-4 KLF4 Krueppel-like factor 4 1 GS(0.971)PDGS(0.029)HPVVVAPYNGGPPR 159.04 1.0713e-20 0.0 761.91 2754.0 3387.6 2607.3 2961.3 2487.3 2417.2 4139.1 1544.0 2449.0 True False 751.0450236828179 2747.6232822052543 3109.0846045141566 2799.04953969783 2787.122156139806 2380.9239771794937 2542.3507885495656 4331.417696527443 1370.098460959204 2872.3063869126227 0.2614780328118475 0.9565912935766622 1.0824348748728165 0.9744954620619234 0.9703429163542754 0.8289240966868772 0.885125208137103 1.5079929203455158 0.47700289467792184 1.0 11.487993933301972 -4.761909001520176 6.4603367806848695 0.9793965954731233 0.24100513716949923 0.43579453480957164 0.2396864369891578 0.10669540835849817 20.672687003491085 0.05568677589340656 0.34744515892371425 1.7301788486273312e-05 4.761909001520176 -0.7383914583036241 GS(ph)PDGSLQTGKPSAPK ddPTM_PC-9_AZD4547_30min_R2 4 GSPDGSLQTGKPSAPK 16 1 Q8IZL8;C9JFV4;E7EV54 Q8IZL8 PELP1 Proline-, glutamic acid- and leucine-rich protein 1 1 GS(0.956)PDGS(0.044)LQTGKPSAPK;GS(0.956)PDGS(0.043)LQTGKPSAPK;GS(0.996)PDGS(0.004)LQTGKPSAPK;GS(0.993)PDGS(0.007)LQTGKPSAPK 160.79 0.00015057 140931000.0 145310.0 169176.0 207487.0 173942.0 174385.0 221154.0 173040.0 221356.0 172883.0 166322.0 True False 191515.55736423863 223858.83358300794 204735.58681040248 133842.35927711087 150174.65285420965 207325.20541931724 188440.22477710227 187150.51645484922 182021.24243236033 160499.11740447688 1.1932499097898253 1.3947667576193397 1.2756181474471566 0.8339133662636423 0.9356727643289878 1.2917529315555862 1.1740888537237901 1.1660532436649333 1.1340949743271493 1.0 17.292205838328407 -5.555516074695018 24.99995234153622 1.08783944783388 1.3043047483372128 0.3492785554083987 0.1315834776135503 214.18690482988276 164064.67515281955 0.038489059645085345 0.06666554665923624 2.782812370729419e-06 5.555516074695018 0.2164653005033328 GS(ph)PDGSLQTGKPSAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GSPDGSLQTGKPSAPK 16 1 Q8IZL8;C9JFV4;E7EV54 Q8IZL8 PELP1 Proline-, glutamic acid- and leucine-rich protein 1 1 GS(0.939)PDGS(0.058)LQT(0.002)GKPSAPK;GS(0.995)PDGS(0.005)LQTGKPSAPK;GS(1)PDGSLQTGKPSAPK 205.12 3.1058e-16 149883000.0 58890.0 72521.0 67521.0 63355.0 68335.0 53549.0 68865.0 40995.9 50598.0 43197.1 True False 68858.91386948162 79720.40560540809 69130.95671481862 59805.4247496813 54945.24729690206 50740.7961723731 62341.60866057569 39919.80106374656 51337.900027988464 51028.392281944536 1.349423542270723 1.5622754713676468 1.3547547477657715 1.1720029198498254 1.0767583464773087 0.9943639982231383 1.2217043467903677 0.7823056788303215 1.0060654026553262 1.0 15.63901256794241 -5.905187447786043 1.4034008024615767 0.999838822231826 1.4706121484137729 0.7332048995003915 0.11141269809000132 0.2131810638209557 0.8523615117050118 0.03863695331495604 0.07710292099214533 1.2439775771513361e-06 5.905187447786043 0.4707733261819469 GS(ph)PDGSLQTGKPSAPK ddPTM_PC-9_Lapatinib_30min_R1 2 GSPDGSLQTGKPSAPK 16 1 Q8IZL8;C9JFV4;E7EV54 Q8IZL8 PELP1 Proline-, glutamic acid- and leucine-rich protein 1 1 GS(0.994)PDGS(0.006)LQTGKPSAPK;GS(1)PDGSLQTGKPSAPK 158.14 0.00023071 65246000.0 81749.0 104130.0 85896.0 86607.0 99085.0 88288.0 97185.0 113524.0 97729.0 80543.0 True False 80583.24426906928 103888.89338272829 78833.96244814851 92976.36769248261 93257.01510860525 84512.12804938013 102216.76377014302 118798.73947973756 86721.7308880065 94464.75023319875 0.8530509430251906 1.099763595693259 0.8345331168879019 0.9842440430208954 0.9872149651418963 0.8946419467658651 1.0820624996922916 1.2575986194476472 0.9180327124554124 1.0 16.527488463900603 -7.278735937218948 22.44751464448428 1.085890092796765 0.9484591708641658 0.22583555173232817 0.10756646709710689 289.2110486901387 375334.7005589452 0.04246545650898242 0.0287435375199407 5.263371963565517e-08 7.278735937218948 -0.1374309219325992 GS(ph)PDGSLQTGKPSAPKK ddPTM_PC-9_Lapatinib_30min_R1 2 GSPDGSLQTGKPSAPKK 17 2 Q8IZL8;C9JFV4;E7EV54 Q8IZL8 PELP1 Proline-, glutamic acid- and leucine-rich protein 1 1 GS(0.893)PDGS(0.08)LQT(0.026)GKPSAPKK;GS(0.9)PDGS(0.098)LQT(0.002)GKPSAPKK 88.54799999999999 0.0076108 49588000.0 255440.0 177143.0 162601.0 166347.0 158253.0 171755.0 137478.0 117695.0 188564.0 117720.0 True False 251797.37875804125 176732.83626713304 149232.5734380111 178580.7132973246 148944.86967736905 164409.43903046026 144595.93815497964 123163.53936672129 167325.93665305138 138067.74514795968 1.8237234083036824 1.2800443440119782 1.0808648557133071 1.2934281870537494 1.0787810687988926 1.1907881804998817 1.0472825351064006 0.8920515014910516 1.211911851488103 1.0 17.075016796565748 -2.1013942529424665 1.0032007410909767 1.0870130332870926 199.99999999991832 0.8041430009713657 0.10753442788613263 188.67197187255317 0.9533437034862429 0.034315010717262985 85374.59638475593 0.00791782223473614 2.1013942529424665 198.91298696663122 GS(ph)PEEELPLPAFEK ddPTM_PC-9_AZD4547_30min_R2 6 GSPEEELPLPAFEK 14 0 Q5JTD0-4;Q5JTD0-2;Q5JTD0 Q5JTD0-4 TJAP1 Tight junction-associated protein 1 1 GS(1)PEEELPLPAFEK;GS(1)PEEELPLPAFEK;GS(1)PEEELPLPAFEK;GS(1)PEEELPLPAFEK;GS(1)PEEELPLPAFEK;GS(1)PEEELPLPAFEK 210.37 3.2754e-11 74971800.0 179561.1 201317.6 234216.6 272752.69999999995 259651.9 265811.9 226393.30000000002 288781.0 256107.9 240347.0 True False 236657.79469710076 266389.5772197628 231110.73484959197 209873.7790022078 223603.71560303902 249190.63987266383 246541.86511806442 244156.5319772124 269645.24073935935 231932.5246859337 1.0203734686093109 1.1485649870818608 0.9964567719104747 0.9048915381161127 0.9640895165774057 1.0744100690927236 1.0629896149835545 1.0527050154256354 1.1626021020747026 1.0 17.823345622634825 -6.790766490880904 23.936494837622654 1.0733635164805346 1.008502346820606 0.1781838497361108 0.06818539639584134 258.04244695481987 210609.01423211306 0.02607043706182417 0.022996555528812343 1.6189502721376454e-07 6.790766490880904 -0.06486116965992861 GS(ph)PEEELPLPAFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GSPEEELPLPAFEK 14 0 Q5JTD0-4;Q5JTD0-2;Q5JTD0 Q5JTD0-4 TJAP1 Tight junction-associated protein 1 1 GS(1)PEEELPLPAFEK;GS(1)PEEELPLPAFEK;GS(1)PEEELPLPAFEK;GS(1)PEEELPLPAFEK;GS(1)PEEELPLPAFEK 205.26 9.857799999999998e-11 62638200.0 188604.0 214607.3 227254.0 226546.0 251625.0 184591.6 221792.0 190246.0 190945.0 174025.0 True False 220530.93210120036 235912.09445376476 232672.59722559428 213853.36209204185 202320.88755517665 174911.29154106014 200782.25612497452 185252.2440822987 193737.20939254994 205574.35491885786 1.0727550729187305 1.1475755064238509 1.131817231373205 1.0402725679302351 0.9841737683430145 0.8508419817739391 0.9766892188679136 0.9011447179557952 0.942419152763582 1.0 17.649300776230206 -6.1500993777943735 2.136326017769323 0.930885269813111 1.1195597933897987 0.7651706971927658 0.043874159931413616 0.13648916582058998 1.22432407010489 0.013802334886720799 0.01930359928273337 7.077838066369714e-07 6.1500993777943735 0.18867452357668768 GS(ph)PEEELPLPAFEK ddPTM_PC-9_Lapatinib_30min_R1 8 GSPEEELPLPAFEK 14 0 Q5JTD0-4;Q5JTD0-2;Q5JTD0 Q5JTD0-4 TJAP1 Tight junction-associated protein 1 1 GS(1)PEEELPLPAFEK;GS(1)PEEELPLPAFEK;GS(1)PEEELPLPAFEK;GS(1)PEEELPLPAFEK;GS(1)PEEELPLPAFEK;GS(1)PEEELPLPAFEK;GS(1)PEEELPLPAFEK;GS(1)PEEELPLPAFEK 238.07 4.8151e-27 60400670.0 158594.8 194398.80000000002 214992.30000000002 185803.9 217770.30000000002 210988.7 187815.6 200531.59999999998 215520.9 183806.3 True False 156333.20906927573 193948.68152242637 197316.46298827705 199468.53862964 204961.47910688282 201965.20513968187 197539.7727792113 209849.03021259722 191246.66670630992 215576.97404850062 0.7251850980805761 0.8996725293991357 0.9152947055648193 0.9252775696942637 0.9507577514320731 0.9368588924262553 0.9163305758933636 0.9734297048133966 0.8871386545359113 1.0 17.717843565328373 -4.127163845218655 1.3366345188435778 0.9386938041776463 2.6284843009473825e-12 0.8192734116563364 0.02991089804433035 2.4004410491589043 1.086883066056765 0.007907808283517365 4.702983273627395 7.46167200624432e-05 4.127163845218655 -0.9386938041750178 GS(ph)PETNHLIR ddPTM_PC-9_Lapatinib_30min_R1 1 GSPETNHLIR 10 0 E9PEI0;Q69YH5 E9PEI0 CDCA2 Cell division cycle-associated protein 2 1 GS(1)PETNHLIR 115.92 0.0006142000000000001 2045900.0 7019.5 8007.9 5812.6 8036.2 7055.8 7379.1 4872.1 4737.6 6396.0 5627.2 True False 6919.400642781356 7989.358199553907 5334.71046528486 8627.208955977332 6640.7917162365275 7063.513094522256 5124.353498631611 4957.726191459113 5675.615127134116 6599.854022227318 1.0484172255140574 1.2105355925520394 0.808307342453084 1.3071817841610114 1.0062028181034517 1.070252928433478 0.7764343698169016 0.7511872497122262 0.8599607064064593 1.0 12.688218399475938 -7.253116559437527 23.763919998484756 0.8261611842601745 1.0765873252167915 0.3956714444633336 0.1372348151942056 287.0358531541757 819567.4196231435 0.05041849805070712 0.03833807936701878 5.583203281372948e-08 7.253116559437527 0.25042614095661697 GS(ph)PGGPEFLK ddPTM_PC-9_AZD4547_30min_R2 1 GSPGGPEFLK 10 0 Q4VC44-2;Q4VC44;Q4VC44-4;I3L188 Q4VC44-2 FLYWCH1 FLYWCH-type zinc finger-containing protein 1 1 GS(1)PGGPEFLK 125.97 0.00036173 11162000.0 33416.0 36463.0 49926.0 50151.0 45185.0 43052.0 39854.0 63971.0 40045.0 40598.0 True False 44041.59290402166 48248.951677171775 49263.94861893112 38589.46177522613 38911.842699873596 40359.95163421165 43400.92879257176 54085.75185733923 42161.69694651222 39176.67637706946 1.124178898692889 1.2315733783229355 1.257481572575816 0.9850111174263105 0.993240016722019 1.030203564124566 1.1078256964640012 1.3805599877021781 1.076193818503448 1.0 15.257707388749921 -10.464999578287541 0.009456975493250842 2.0176095113997307e-05 2.165887238633397 0.054288451873661936 0.12226190607457361 27716.681497391997 51.01907418620859 6167.665137300655 5526.048465793077 3.427681193840117e-11 10.464999578287541 2.165867062538283 GS(ph)PGGPEFLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GSPGGPEFLK 10 0 Q4VC44-2;Q4VC44;Q4VC44-4;I3L188 Q4VC44-2 FLYWCH1 FLYWCH-type zinc finger-containing protein 1 1 GS(1)PGGPEFLK;GS(1)PGGPEFLK;GS(1)PGGPEFLK 104.17 0.0026436 11145500.0 53666.0 58801.0 58204.0 59293.0 59067.0 42815.0 56716.0 45554.0 45378.0 37483.0 True False 62750.59384818482 64638.374677729116 59591.80409989919 55971.005440499626 47493.24536600735 40569.706028500164 51343.44989171867 44358.25576845272 46041.56740325825 44278.37118473525 1.4171838793794151 1.4598182577233751 1.3458445400187433 1.2640710112614835 1.0726059720638597 0.9162420600170218 1.1595604923565723 1.0018041445875274 1.0398207109102253 1.0 15.434314531955147 -6.0260707147059005 1.7327374260498238 1.0270546092851713 1.429064217082003 0.8906378295020185 0.0603412166664971 0.1084020325604704 0.6535720921642906 0.020216307226038115 0.03272911934160761 9.41736244301461e-07 6.0260707147059005 0.4020096077968316 GS(ph)PGGPEFLK ddPTM_PC-9_Lapatinib_30min_R1 2 GSPGGPEFLK 10 0 Q4VC44-2;Q4VC44;Q4VC44-4;I3L188 Q4VC44-2 FLYWCH1 FLYWCH-type zinc finger-containing protein 1 1 GS(1)PGGPEFLK;GS(1)PGGPEFLK 158.3 0.00012369 16040800.0 52983.0 76785.0 77924.0 70581.0 74570.0 73437.0 79049.0 67706.0 85225.0 56875.0 True False 52227.4527041078 76607.20905015651 71517.3895153385 75771.76219131389 70183.93921026071 70296.27070000827 83141.77043027245 70851.86793290506 75626.06304096385 66705.76796882616 0.7829525735842731 1.1484345564533134 1.0721320163611785 1.1359101993507454 1.0521419863280792 1.0538259709843993 1.2463955211358542 1.062155044313657 1.1337259931750798 1.0 16.02552389448614 -4.756633727670226 24.999819049366476 1.1042726528297735 0.7829520859855484 0.6784448523439299 0.06554373662280477 81.8638348769769 425819.5577081331 0.015487785487416047 0.12321459929744986 1.75132308492638e-05 4.756633727670226 -0.32132056684422505 GS(ph)PGVSQR ddPTM_PC-9_AZD4547_30min_R2 1 GSPGVSQR 8 0 C9JIE2;Q86TI0-2;Q86TI0;H7C380;H7C0Z7;H0Y8P0;H0YA01 C9JIE2 TBC1D1 TBC1 domain family member 1 1 GS(1)PGVSQR 92.23899999999999 0.0081241 4378400.0 9667.0 10551.0 12379.0 15602.0 12001.0 20402.0 18536.0 14928.0 18683.0 18749.0 True False 12740.904913908827 13961.404413949464 12214.846371705084 12005.199948497098 10334.868302338891 19126.25971479109 20185.66809100994 12621.22061131388 19670.545237899554 18092.60321675146 0.7042051804967658 0.7716636598222069 0.6751292904271333 0.6635418797766925 0.5712206352245713 1.0571314412667048 1.1156862198978954 0.6975900847495637 1.0872147585532146 1.0 14.143112381632314 -6.765358224968724 24.99999671716741 0.9803840123906432 0.6815342560631239 0.64240053856307 0.11710597763578401 69.74585453151116 444935.2636272251 0.040974005986840575 0.037478438863026174 1.7164919658805943e-07 6.765358224968724 -0.2988497563275193 GS(ph)PGVSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSPGVSQR 8 0 C9JIE2;Q86TI0-2;Q86TI0;H7C380;H7C0Z7;H0Y8P0;H0YA01 C9JIE2 TBC1D1 TBC1 domain family member 1 1 GS(1)PGVSQR;GS(1)PGVSQR 99.788 0.0050921000000000004 8961700.0 18048.7 34882.0 34730.0 27859.0 52052.0 36837.0 23424.0 23648.0 32500.0 37758.0 True False 21103.98843192585 38344.85443289305 35558.094914258465 26298.150550096616 41852.78425840847 34905.202872167705 21205.109144925922 23027.265057127133 32975.25101604067 44603.22650783645 0.4731493679771807 0.8596879067965217 0.7972090294412036 0.5896019774595506 0.938335352287917 0.7825712533606761 0.4754164845271977 0.5162690428478625 0.7393019204619012 1.0 15.444860455132005 GS(ph)PGVSQR ddPTM_PC-9_Lapatinib_30min_R1 2 GSPGVSQR 8 0 C9JIE2;Q86TI0-2;Q86TI0;H7C380;H7C0Z7;H0Y8P0;H0YA01 C9JIE2 TBC1D1 TBC1 domain family member 1 1 GS(0.998)PGVS(0.002)QR;GS(0.999)PGVS(0.001)QR 90.149 0.009692000000000001 9976200.0 15350.7 40094.0 27108.0 30508.0 48367.0 31045.0 37829.0 45673.0 34153.0 26298.0 True False 15131.796203026382 40001.164806368 24879.284879906052 32751.660091704594 45522.14815318069 29717.277719429665 39787.60052128141 47795.13431748397 30306.329492966153 30843.574260117628 0.4905980116121819 1.2969043233777098 0.8066278139520388 1.061863317639364 1.475903790179183 0.9634835920380238 1.2899802138926837 1.5495977837849229 0.9825816306949172 1.0 14.912682338983803 -4.754849085469522 24.998583781331163 1.1696338832385131 0.49059686784019063 0.4357586699980619 0.22770704813009177 215.00669824244002 815498.0988413913 0.05664777765815939 0.5307601962783437 1.758534587221247e-05 4.754849085469522 -0.6790370153983225 GS(ph)PHY(ph)FSPFRPY ddPTM_PC-9_AZD4547_30min_R2 5 GSPHYFSPFRPY 12 1 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 2 GS(1)PHY(0.837)FS(0.163)PFRPY;GS(1)PHY(0.718)FS(0.282)PFRPY;GS(1)PHY(0.532)FS(0.469)PFRPY;GS(1)PHY(0.793)FS(0.206)PFRPY(0.001);GS(1)PHY(0.865)FS(0.135)PFRPY 95.428 0.0067577 0.0 13374.89 13253.489999999998 21770.7 28959.8 26710.9 25365.2 18218.649999999998 27146.5 18294.7 21248.5 True False 17627.826805005683 17537.421456377127 21482.006293277307 22283.565534449823 23002.55259869543 23779.110034193658 19840.074555798357 22951.632189511805 19261.72049262971 20504.596482540037 0.859701229429998 0.8552922010101733 1.0476678393339536 1.0867595250374522 1.1218242026017162 1.15969656142426 0.9675915628328736 1.1193408370194193 0.9393854938345821 1.0 14.323659732170123 -5.278597512373256 5.109776861549114 1.0645669137783365 0.8551777428002654 0.5788311288442215 0.06721242887658685 0.10894177706157926 8.895000008857375 0.01730506236420261 0.04070176704678256 5.265049851742263e-06 5.278597512373256 -0.20938917097807108 GS(ph)PHY(ph)FSPFRPY ddPTM_PC-9_Lapatinib_30min_R1 3 GSPHYFSPFRPY 12 1 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 2 GS(1)PHY(0.816)FS(0.184)PFRPY;GS(1)PHY(0.812)FS(0.188)PFRPY;GS(1)PHY(0.613)FS(0.387)PFRPY 90.759 0.020730000000000002 2736600.0 12981.8 14122.400000000001 13943.9 11078.2 10576.5 14924.7 12008.4 11934.0 11914.900000000001 9833.9 True False 12796.677151429443 14089.700450477665 12797.48636701056 11892.927783791847 9954.411064199046 14286.405372174959 12630.136194447545 12488.497207208931 10572.918492540693 11533.676512151913 1.109505467571145 1.22161397847709 1.109575628684149 1.031148027366766 0.8630735441306207 1.238668811035472 1.0950659298568326 1.0827854582232315 0.9166997601676307 1.0 13.493564844003634 -1.522878747353129 0.26035775466784283 1.0139064590275044 2.075560407222759 0.1627609293070117 0.10351407098544203 103.4870649794945 1.4286812228288468 0.1331135928095244 48.76785329409352 0.02999999985681665 1.522878747353129 1.0616539481952545 GS(ph)PHYFS(ph)PFRPY ddPTM_PC-9_AZD4547_30min_R2 4 GSPHYFSPFRPY 12 1 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 2 GS(1)PHY(0.024)FS(0.976)PFRPY;GS(1)PHY(0.323)FS(0.677)PFRPY;GS(1)PHY(0.06)FS(0.94)PFRPY;GS(1)PHY(0.061)FS(0.939)PFRPY 83.823 0.025049000000000002 39050000.0 46208.86 39918.0 49616.9 81426.6 72563.1 59646.6 61092.54 67656.1 51431.5 48427.7 True False 60902.3162760034 52820.71286096433 48958.94748689347 62654.955398429374 62488.96609527938 55916.888672887886 66529.65770806797 57201.40432751296 54150.06409051173 46732.26096324467 1.3032178418224534 1.130283700643294 1.0476477379384685 1.3407216793492625 1.337169758262445 1.1965371997915317 1.423634472990599 1.2240239001597282 1.1587298147868605 1.0 15.512131217769765 -8.594484339834757 2.4206157144410163 1.001020542125298 1.2492384803889591 0.35596721193597225 0.10371577677001874 0.4380008346902569 5.95425647877032 0.10552927638283129 0.028681289832436098 2.543991524917893e-09 8.594484339834757 0.24821793826366112 GS(ph)PHYFS(ph)PFRPY ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSPHYFSPFRPY 12 1 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 2 GS(1)PHY(0.409)FS(0.591)PFRPY 82.34899999999999 0.039302 1224200.0 2526.7 1076.6 2181.6 2806.4 3214.7 2877.9 2268.2 1171.6 2136.0 1973.5 True False 2954.4204054002266 1183.477732998472 2233.617617764072 2649.1665064715594 2584.8026119170404 2726.9778577465977 2053.3396756540724 1140.846741412811 2167.234959085012 2331.2799277825966 1.2672954329471415 0.5076514917383346 0.9581078578961487 1.136357103623897 1.1087482807676308 1.1697341984754144 0.880777829888113 0.489364974071531 0.9296330883551954 1.0 11.186906530731902 -7.521506619398191 24.997862196674966 0.7627136992361697 1.0085441722216533 0.14835463236186186 0.23057214575957566 92.49574850000208 1685224.5034964725 0.10749380426454894 0.06316261788146559 3.0094932986465625e-08 7.521506619398191 0.24583047298548355 GS(ph)PHYFS(ph)PFRPY ddPTM_PC-9_Lapatinib_30min_R1 5 GSPHYFSPFRPY 12 1 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 2 GS(1)PHY(0.091)FS(0.909)PFRPY;GS(1)PHY(0.254)FS(0.746)PFRPY;GS(1)PHY(0.086)FS(0.914)PFRPY;GS(1)PHY(0.025)FS(0.975)PFRPY;GS(0.999)PHY(0.03)FS(0.97)PFRPY 97.823 0.012395 38991100.0 64432.8 65958.0 73200.5 53266.1 71789.59999999999 69976.9 61045.9 58501.8 69989.0 49377.9 True False 63513.97645647165 65805.27830344734 67182.2374521015 57183.466684500665 67567.0768717841 66984.15111112116 64206.5580021173 61220.00719932087 62106.10180315662 57912.804223084 1.0967173375306014 1.1362820223652268 1.1600584422282683 0.9874062817650155 1.1667035947959141 1.1566380183058262 1.1086763775898218 1.057106593621288 1.0724070891804818 1.0 15.821594735482407 -8.38128272899268 1.0899006958064568 1.0042688380700335 1.11679936916953 0.33225033547422356 0.05011313616317124 0.5821680909706549 1.4824314377550545 0.04809467615792938 0.015797387383683352 4.156399376552754e-09 8.38128272899268 0.1125305310994964 GS(ph)PHYFSPFRPY ddPTM_PC-9_AZD4547_30min_R2 10 GSPHYFSPFRPY 12 1 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 1 GS(0.999)PHY(0.001)FSPFRPY;GS(1)PHYFSPFRPY;GS(1)PHYFSPFRPY;GS(1)PHYFSPFRPY;GS(0.997)PHY(0.003)FSPFRPY;GS(1)PHYFSPFRPY;GS(1)PHYFSPFRPY;GS(1)PHYFSPFRPY;GS(1)PHYFSPFRPY;GS(0.999)PHY(0.001)FSPFRPY 158.01 0.0020658 1848036800.0 71100.32 70400.61 135114.83 189220.81999999998 157898.59999999998 133936.61000000002 92561.1 148256.51 113321.58999999998 121945.35999999999 True False 93708.74278147181 93156.2304235366 133323.11907173833 145598.88338152654 135977.10491823105 125561.53260360222 100798.8585853898 125346.87297517808 119311.53789678875 117676.09006367887 0.7963278073800936 0.7916326109503327 1.132966934910841 1.237285189393509 1.155520249225215 1.0670097258980669 0.8565789238140374 1.0651855691954777 1.0138978770642777 1.0 16.84446169157853 -5.25348893596396 24.265533138805775 1.0702468961608766 0.7939801414281221 0.560083391211313 0.09639404022511441 316.3963431229892 965663.3288400262 0.027714968914272536 0.07044822254133958 5.5784181347376104e-06 5.25348893596396 -0.2762667547327545 GS(ph)PHYFSPFRPY ddPTM_PC-9_LapatinibAZD4547_30min_R1 12 GSPHYFSPFRPY 12 1 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 1 GS(0.996)PHYFS(0.004)PFRPY;GS(1)PHYFSPFRPY;GS(1)PHYFSPFRPY;GS(1)PHYFSPFRPY;GS(1)PHYFSPFRPY;GS(0.854)PHY(0.128)FS(0.018)PFRPY;GS(0.985)PHYFS(0.015)PFRPY;GS(1)PHYFSPFRPY;GS(0.988)PHY(0.011)FSPFRPY;GS(0.973)PHYFS(0.027)PFRPY;GS(0.999)PHY(0.001)FSPFRPY;GS(0.998)PHY(0.002)FSPFRPY 124.21 0.0015888 1295524400.0 166289.8 154313.1 251227.6 247037.44999999998 298622.0 260923.92999999996 238558.76999999996 217745.69999999998 235798.59999999998 176015.7 True False 194439.37876674006 169632.28474825024 257217.81876997804 233196.7425827194 240109.16277596363 247240.6197804728 215960.75628967254 212030.10609564016 239246.7084378764 207925.95307048503 0.9351376097856666 0.8158302618949469 1.2370645173033474 1.1215374470529313 1.154782071358686 1.1890801322750721 1.038642618203913 1.019738531744346 1.1506341796436248 1.0 17.665710319353785 -5.252436219410891 24.994233101651886 1.1163649757504528 0.875483918016326 0.6082264629982321 0.07652990743171298 418.0957842053966 1160695.738498834 0.019631327103800236 0.05032537021917962 5.591956451436424e-06 5.252436219410891 -0.24088105773412682 GS(ph)PHYFSPFRPY ddPTM_PC-9_Lapatinib_30min_R1 8 GSPHYFSPFRPY 12 1 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 1 GS(1)PHYFSPFRPY;GS(0.96)PHYFS(0.04)PFRPY;GS(0.995)PHYFS(0.005)PFRPY;GS(1)PHYFSPFRPY;GS(1)PHYFSPFRPY;GS(1)PHYFSPFRPY;GS(0.987)PHY(0.012)FS(0.001)PFRPY;GS(1)PHYFSPFRPY 132.86 0.00036037 1852446000.0 216433.0 149012.0 247013.31 176479.1 215786.25999999998 206503.1 161327.4 169742.7 221393.3 151223.80000000002 True False 213346.62573104896 148666.97186926994 226704.82915075027 189457.96173101937 203094.1364389099 197671.4437952375 169680.14339096943 177629.56551819207 196457.65517919633 177362.63233695252 1.2028837355420743 0.8382090968678976 1.2781995066472498 1.068195477450336 1.145078496879054 1.1145044544653713 0.9566848504402667 1.0015050136419517 1.10766091250815 1.0 17.436342561748837 -7.238505934498554 24.033189863760715 1.0165881050133188 1.1032225042439319 0.13622008150889053 0.1123711901683663 1047.3096113283239 1097533.1829324602 0.04136823768442393 0.032018795060364154 5.77422982355233e-08 7.238505934498554 0.08663439923061311 GS(ph)PLAEGPQAFFPER ddPTM_PC-9_AZD4547_30min_R2 3 GSPLAEGPQAFFPER 15 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 GS(1)PLAEGPQAFFPER;GS(1)PLAEGPQAFFPER;GS(1)PLAEGPQAFFPER 195.46 1.2007999999999998e-09 21145200.0 7075.9 8105.4 10393.5 8087.200000000001 12555.0 10234.400000000001 9147.900000000001 11689.300000000001 11535.599999999999 7450.299999999999 True False 9325.889012136899 10725.31204026405 10255.675399007747 6222.820985994474 10811.954965074976 9594.441350115572 9962.045378169505 9882.987278391704 12145.348265605842 7189.4672646948275 1.2971599520222248 1.49180900967901 1.4264861388784793 0.8655468836408444 1.5038603789419873 1.3345135316535626 1.3856444450467034 1.3746480670304866 1.689325205672437 1.0 12.8116691564313 GS(ph)PLAEGPQAFFPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GSPLAEGPQAFFPER 15 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 GS(1)PLAEGPQAFFPER;GS(1)PLAEGPQAFFPER;GS(1)PLAEGPQAFFPER;GS(1)PLAEGPQAFFPER 102.72 0.0014254 16029800.0 3208.88 5534.28 4528.139999999999 3662.0 13679.199999999999 10480.3 9570.6 9060.84 10590.07 10902.23 True False 3752.0800057310635 6083.686743617665 4636.10803066658 3456.8300123641857 10998.858956958833 9930.694618486275 8664.003482856382 8823.002550753548 10744.929739305904 12878.717996994803 0.2913395577577362 0.4723829456501237 0.35998210627396277 0.26841413975916106 0.8540336825082568 0.7710934132421847 0.672738038435044 0.6850839154030984 0.8343167186216198 1.0 13.65270136807725 -6.262623623424115 24.999996670878097 0.7790356420824825 0.35776579789587665 0.8267813937309856 0.10160381113917254 45.38834576006347 958169.5321235745 0.03069188142675049 0.036785230141950405 5.462310411975703e-07 6.262623623424115 -0.4212698441866059 GS(ph)PLAEGPQAFFPER ddPTM_PC-9_Lapatinib_30min_R1 4 GSPLAEGPQAFFPER 15 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 GS(1)PLAEGPQAFFPER;GS(1)PLAEGPQAFFPER;GS(1)PLAEGPQAFFPER;GS(1)PLAEGPQAFFPER 170.47 7.7445e-05 16500900.0 4896.6 4475.0 6134.200000000001 4182.99 9152.3 9931.2 9085.42 10177.5 9671.69 11210.0 True False 4826.773586073537 4464.6384124431825 5629.8697546967605 4490.62103864558 8613.979708114119 9506.465726757922 9555.818592298521 10650.383804790421 8582.362424789204 13147.633563613921 0.36712109161846695 0.3395773384496409 0.4282040359169597 0.3415535591951219 0.6551733942413264 0.7230552692818477 0.7268090144179445 0.8100608944765056 0.6527686053360122 1.0 13.682515532430783 -6.418560539796744 2.300722347418562 0.7700657049827313 0.3659022732903523 0.8254028261840962 0.08955433417412641 0.11987115949101625 1.2488346834785515 0.029271483208103372 0.03366592048086331 3.8145161696783187e-07 6.418560539796744 -0.404163431692379 GS(ph)PLLGPVVPGPSPIPSVTEK ddPTM_PC-9_AZD4547_30min_R2 2 GSPLLGPVVPGPSPIPSVTEK 21 0 P49454 P49454 CENPF Centromere protein F 1 GS(1)PLLGPVVPGPSPIPSVTEK;GS(1)PLLGPVVPGPSPIPSVTEK 156.51 1.0453e-05 6798000.0 59213.0 60526.0 60214.0 40781.0 48350.0 59579.0 54285.0 72705.0 55673.0 53425.0 True False 78041.5022930882 80089.84584955985 59415.5230168713 31379.570510169222 41637.437081750315 55853.515711574284 59116.25983602045 61470.11284469289 58615.76112131783 51554.60701130443 1.51376388682346 1.5534954195654807 1.1524774692559134 0.608666661027764 0.8076375613263899 1.083385539129941 1.1466726886902263 1.1923301603523866 1.1369645608677628 1.0 15.653813734696302 -5.359130452435038 4.16264525262668 0.9994725078780311 1.534365745031659 0.6129321580670744 0.16752124505162908 0.15983795156901393 4.80777639341437 0.051067845304323366 0.11509395044934775 4.373907029528799e-06 5.359130452435038 0.5348932371536279 GS(ph)PLLGPVVPGPSPIPSVTEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSPLLGPVVPGPSPIPSVTEK 21 0 P49454 P49454 CENPF Centromere protein F 1 GS(1)PLLGPVVPGPSPIPSVTEK 144.74 2.4454999999999998e-11 0.0 15344.0 18555.0 15072.0 11328.0 13435.0 11302.0 13812.0 8634.8 9356.7 7768.2 True False 17941.43614218588 20397.01777427702 15431.373640878313 10693.328885871513 10802.508193954473 10709.303223966104 12503.627369779571 8408.14564932685 9493.524036362702 9176.513166962635 1.9551474308105175 2.2227416234426105 1.6816162479267707 1.1652932536913618 1.17719094359781 1.1670340388680347 1.3625684551726294 0.9162680308243802 1.0345458959881813 1.0 13.163730356348333 -5.5980794495385195 2.6295888924441053 1.1221726288295795 2.0878031275201305 0.9010054444573788 0.1313299162891687 0.0776355685047762 1.078060092432839 0.03844443207622082 0.0800749539398959 2.523019170840185e-06 5.5980794495385195 0.9656304986905511 GS(ph)PLLGPVVPGPSPIPSVTEK ddPTM_PC-9_Lapatinib_30min_R1 2 GSPLLGPVVPGPSPIPSVTEK 21 0 P49454 P49454 CENPF Centromere protein F 1 GS(1)PLLGPVVPGPSPIPSVTEK;GS(1)PLLGPVVPGPSPIPSVTEK 118.23 2.6162e-06 4298200.0 6991.2 20977.0 23983.0 16200.1 24272.0 27178.0 25590.0 25959.0 24024.0 21164.6 True False 6891.504205970938 20928.42904532304 22011.210317057208 17391.509395949375 22844.368680588024 26015.660295012356 26914.92498716836 27165.149907988653 21318.164136064708 24822.872909943177 0.27762718001953923 0.8431106714058001 0.8867309757784033 0.7006243579881095 0.9202951150524308 1.0480519474678287 1.08427920832593 1.0943596257590007 0.8588113154108522 1.0 14.599382477010888 -4.6862092309769094 2.131697116278316 0.9532523664843113 1.1243055557974774e-106 0.7583572398830185 0.1129639346685595 0.5206894074246555 2.1560135422412787 0.03378118502613178 1.0493221959616674 2.0596373983130082e-05 4.6862092309769094 -0.9532523664843113 down GS(ph)PLNAAPYGIESMSQDTEVR ddPTM_PC-9_AZD4547_30min_R2 1 GSPLNAAPYGIESMSQDTEVR 21 0 B4DSN5;P18031 B4DSN5 PTPN1 Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 1 1 GS(0.999)PLNAAPYGIES(0.001)MSQDTEVR 108.96 0.00098634 0.0 9358.4 10990.0 14687.0 8371.4 9217.9 9793.1 12542.0 15311.0 13635.0 7356.5 True False 12334.176533187576 14542.302578836574 14492.240783684681 6441.503066840702 7938.153697536008 9180.735908877597 13658.213702926561 12945.036761778321 14355.7182635958 7098.951174144328 1.7374646240857228 2.0485142413434656 2.041462242544794 0.907387994201429 1.1182150014565824 1.2932524373904004 1.923976284366099 1.8235139873797837 2.022230877693868 1.0 12.79339017580991 -7.272073475214661 24.618716408248932 1.7610564238064927 1.525203134578525 0.025574641893634897 0.4317906682869813 2072.785435013645 4798628.712605416 0.19406465528093342 0.13240432337112018 5.344739278801963e-08 7.272073475214661 -0.23585328922796767 GS(ph)PLPVLSWANR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSPLPVLSWANR 12 0 I3L1Q9;I3L413;C9J2U0;P24864-2;P24864-3;P24864 I3L1Q9 CCNE1 G1/S-specific cyclin-E1 1 GS(1)PLPVLSWANR 84.352 0.037832 0.0 2600.3 6704.3 4640.6 5278.2 6870.2 4494.4 5040.6 5230.2 6442.3 4768.8 True False 3040.4794317339624 7369.858596824865 4751.249503573506 4982.479566155282 5524.033628143352 4258.705752060983 4563.117877216254 5092.912791854972 6536.506449865813 5633.345690199972 0.53972889272947 1.3082560528188092 0.8434152215865253 0.8844618882208903 0.9805955345068236 0.755981611330834 0.8100191481510649 0.9040653764094113 1.1603240435318964 1.0 12.459776289922262 -8.191039126687958 7.463695604929981 1.0792679967519727 0.8882239771125907 0.1574151997234211 0.18576094966315707 0.4750207111160878 44.36783776283694 0.12105088473339633 0.04508264222569434 6.441112332914842e-09 8.191039126687958 -0.191044019639382 GS(ph)PMMNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSPMMNR 7 0 O75376-2;O75376;A0A088AWL3;E7EVK1 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 GS(1)PMMNR;GS(1)PMMNR 69.432 0.027835000000000002 11699000.0 15768.6 14633.6 18936.3 19377.3 24262.0 16783.9 15300.5 17120.0 16233.2 13853.0 True False 18437.912535953605 16086.32709790677 19387.81320831766 18291.65270305422 19508.035266224288 15903.722737632681 13851.125873972805 16670.61814013941 16470.57983980282 16364.439239712347 1.1267060402051214 0.983005091849975 1.1847526777005808 1.1177683778289826 1.1920992207837608 0.9718464839930706 0.8464161631863091 1.0187100148035653 1.006486051769675 1.0 13.998276545943915 -6.824557019941929 9.045863834821535 0.96168170575224 1.116466704005295 0.5432759423761093 0.06956924416867713 0.256836171339554 34.137264868560024 0.025209110152532528 0.02226170031188573 1.4977625939890672e-07 6.824557019941929 0.15478499825305492 GS(ph)PMMNR ddPTM_PC-9_Lapatinib_30min_R1 1 GSPMMNR 7 0 O75376-2;O75376;A0A088AWL3;E7EVK1 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 GS(1)PMMNR 67.035 0.031516 2140900.0 7815.1 6038.1 8039.3 5126.2 5858.8 6811.3 4883.5 4959.7 7069.9 5406.0 True False 7703.655240886184 6024.119150429755 7378.339786595425 5503.1978485019 5514.196902843982 6519.996576915803 5136.343734850983 5190.145768275022 6273.61341265251 6340.419896957787 1.2150071077441567 0.950113596312478 1.1636989200250987 0.8679547944675404 0.8696895461907439 1.0283225216746574 0.8100952016309622 0.8185807647795249 0.9894633974735125 1.0 12.630362671272687 -5.767844894082651 24.99998885479669 0.9032919309235642 1.0936572552495434 0.4702953443069171 0.09533441722939874 128.04859358569746 499760.8197268024 0.025780269173021713 0.039309095610230355 1.7066918158899324e-06 5.767844894082651 0.1903653243259792 GS(ph)PNTASAEATLPR ddPTM_PC-9_AZD4547_30min_R2 3 GSPNTASAEATLPR 14 0 Q6PJG6;Q6PJG6-3 Q6PJG6 BRAT1 BRCA1-associated ATM activator 1 1 GS(1)PNTASAEATLPR;GS(0.973)PNT(0.022)AS(0.003)AEAT(0.001)LPR;GS(0.999)PNT(0.001)ASAEATLPR 147.75 2.474e-05 73616500.0 16590.7 15754.599999999999 28528.8 39149.4 24629.9 32793.9 26854.6 27135.9 23956.7 19424.0 True False 21866.19749200239 20846.966352005325 28150.48947161321 30124.11068220052 21210.463528020708 30743.292248842634 29244.60737574644 22942.67017594804 25223.002253427603 18743.971672205455 1.1665722651740205 1.1121957884154456 1.5018422970280219 1.6071359479736163 1.131588539448803 1.640169585532953 1.5602140190550906 1.224002606126888 1.345659430910771 1.0 14.194139058517447 -8.947707713482519 1.3409053569080978 1.0009496987937048 1.3811972034120261 0.24695096149095874 0.19197875988369745 2.604428379144886 6.5443929455939385 0.1921562693235554 0.05689893457055227 1.1279563318343875e-09 8.947707713482519 0.38024750461832135 GS(ph)PNTASAEATLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GSPNTASAEATLPR 14 0 Q6PJG6;Q6PJG6-3 Q6PJG6 BRAT1 BRCA1-associated ATM activator 1 1 GS(0.999)PNTASAEAT(0.001)LPR;GS(1)PNTASAEATLPR;GS(0.999)PNT(0.001)ASAEATLPR 181.69 2.812e-05 66841000.0 51795.7 60085.0 61294.0 58942.0 68085.0 46394.4 58401.1 50912.0 49961.6 34972.6 True False 60563.6889982936 66049.84171206874 62755.48141878945 55639.670832542324 54744.233002262044 43961.39599132655 52868.925020651186 49575.61394572295 50692.193881939 41312.85553705074 1.4659768299961273 1.5987721219810878 1.519030350310892 1.346788308608753 1.325113751896564 1.0641093533682393 1.2797209085011463 1.2000045337282943 1.227031954653354 1.0 15.334303162008394 -6.109380038825413 1.4628942179224076 1.1761940959077237 1.5438008603786655 0.7593344880086634 0.08897117142415498 0.19270598416321671 0.8290571146472828 0.030830199315369334 0.04885391323711032 7.773560110499314e-07 6.109380038825413 0.36760676447094176 GS(ph)PNTASAEATLPR ddPTM_PC-9_Lapatinib_30min_R1 4 GSPNTASAEATLPR 14 0 Q6PJG6;Q6PJG6-3 Q6PJG6 BRAT1 BRCA1-associated ATM activator 1 1 GS(0.995)PNT(0.004)AS(0.001)AEATLPR;GS(1)PNTASAEATLPR;GS(1)PNTASAEATLPR;GS(1)PNTASAEATLPR 178.02 7.9748e-05 75864300.0 43957.2 46088.5 52794.6 44229.0 50150.3 48780.3 38818.7 41897.4 49198.8 40421.899999999994 True False 43330.36226723676 45981.784909918984 48454.03178104944 47481.74820361878 47200.55795328338 46694.08028143324 40828.54234464215 43844.106157978495 43657.51305766823 47408.771556203836 0.9139735294737165 0.9699003665472932 1.0220478234414159 1.0015393068628329 0.9956081206897839 0.9849249147085932 0.8612022839747973 0.9248100028493804 0.9208741678934154 1.0 15.532866390358246 -7.205495326472094 24.49236239873584 0.9204557586643101 0.984230861621409 0.29191705039721916 0.04105907995844804 258.01969814523704 112961.12501716914 0.015639620101304146 0.012114388184617993 6.230238518745789e-08 7.205495326472094 0.06377510295709898 GS(ph)PQAISR ddPTM_PC-9_AZD4547_30min_R2 1 GSPQAISR 8 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 GS(1)PQAISR 123.01 0.0033038000000000004 7237400.0 21136.0 28299.0 37213.0 29258.0 20189.0 33624.0 36118.0 45643.0 26805.0 34467.0 True False 27856.808343889214 37446.09833289321 36719.531305457735 22513.02013159392 17386.10583750687 31521.485964617947 39332.432030162796 38589.923121797925 28221.857576507908 33260.320820938316 0.8375387746215773 1.1258489818691055 1.104004122604306 0.6768732103576504 0.522728145982339 0.9477204424550913 1.1825632182538033 1.160239052700432 0.8485142921033235 1.0 15.021514464126058 -7.004348471885503 24.959720844342478 1.061748052135501 0.8589077504821621 0.19127074175611336 0.18748813988297505 335.1709532827396 1923850.7701542492 0.07471523295557823 0.06431503297159748 9.90037233919678e-08 7.004348471885503 -0.20284030165333888 GS(ph)PQAISR ddPTM_PC-9_Lapatinib_30min_R1 1 GSPQAISR 8 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 GS(1)PQAISR 131.42 0.00396 7827000.0 23134.0 29627.0 28008.0 22595.0 24502.0 41806.0 36762.0 32263.0 32841.0 25062.0 True False 22804.104917743996 29558.400501777454 25705.290354006534 24256.711674710405 23060.840532785416 40018.054834545845 38665.35648215255 33762.05676187213 29142.10074893864 29393.93330698413 0.7758099155898145 1.0055952768578353 0.87451005911818 0.825228506215155 0.7845442218277762 1.3614392608367718 1.3154196166378824 1.1486062926410097 0.9914324988284009 1.0 14.843230803621942 -6.749932147151291 24.999997944543995 1.1821699443349527 0.861244285595868 0.6044734230651275 0.12493140869766625 154.14839290491892 334893.98767008283 0.04308045030996961 0.042724955219819845 1.7785572647093577e-07 6.749932147151291 -0.32092565873908474 GS(ph)PQQIDHAK ddPTM_PC-9_AZD4547_30min_R2 1 GSPQQIDHAK 10 0 A0A087WTP3;Q92945;M0R3J3 A0A087WTP3 KHSRP Far upstream element-binding protein 2 1 GS(1)PQQIDHAK 100.73 0.0021966999999999998 11936000.0 87181.0 81422.0 186790.0 199100.0 184600.0 179750.0 115880.0 212460.0 128800.0 154230.0 True False 114902.74452254965 107740.06920600824 184313.0425535819 153200.57106433617 158971.4764279441 168510.20408458493 126193.09551069459 179629.18884510593 135608.10504958846 148830.4546439588 0.7720378520473309 0.7239114431501975 1.238409457221015 1.0293630522787276 1.0681380824122673 1.13222931749893 0.8478983405149257 1.206938386869984 0.9111583067726182 1.0 17.183310244620614 -5.241764743510422 24.887703902437373 1.0566775724880417 0.7479745649474632 0.5332856362647338 0.1145972755283243 546.5260429376132 691333.0606628774 0.027171241433676274 0.07167489172292875 5.731063975543425e-06 5.241764743510422 -0.30870300754057856 GS(ph)PQQIDHAK ddPTM_PC-9_Lapatinib_30min_R1 1 GSPQQIDHAK 10 0 A0A087WTP3;Q92945;M0R3J3 A0A087WTP3 KHSRP Far upstream element-binding protein 2 1 GS(1)PQQIDHAK 98.0 0.0027930999999999997 11347000.0 90212.0 91145.0 156510.0 94152.0 127680.0 135740.0 87264.0 104880.0 154380.0 77125.0 True False 88925.56033714516 90933.95935243223 143642.35194607105 101076.25216186493 120170.11342853811 129934.71662539478 91782.10293396865 109753.10768326416 136992.09870652994 90455.95348739736 0.9830813441100322 1.0052844046920744 1.5879811820908372 1.1174085095012263 1.3284931372182223 1.436441843968819 1.014660720443968 1.213332052251877 1.5144619389327 1.0 16.4649278385495 -5.04862661766229 24.971347671870838 1.2780647481109704 0.9886313520353553 0.26401680177910114 0.1887568256358624 409.97604472078973 210535.79733908293 0.04591557730104742 0.12148684819326089 8.940738285461983e-06 5.04862661766229 -0.289433396075615 GS(ph)PSFLK ddPTM_PC-9_AZD4547_30min_R2 2 GSPSFLK 7 0 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 GS(0.999)PS(0.001)FLK;GS(0.999)PS(0.001)FLK 86.67 0.018456999999999998 22225000.0 44799.0 72959.0 115633.0 108338.0 142612.0 136020.0 126267.0 169780.0 126291.0 139573.0 True False 59044.15012291311 96541.56995899352 114099.63086673988 83362.34790541467 122812.78546230757 127514.64789755353 137504.51838840952 143544.40215627465 132966.48443181367 134686.59175271468 0.43838179698925406 0.7167867914888245 0.8471491436670061 0.618935759087797 0.9118412149577035 0.9467508698391531 1.0209221021857064 1.0657660891725804 0.9872288154409673 1.0 17.03924670998316 -4.541250181272911 0.3700035496409964 1.05684268013254 2.2938592764296864e-15 0.790874759615092 0.08803170072429793 3.4455229906295197 0.32806992265581547 0.08168369755347797 1.685088286069452 2.87574132738585e-05 4.541250181272911 -1.0568426801325377 down GS(ph)PSFLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSPSFLK 7 0 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 GS(0.997)PS(0.003)FLK 80.455 0.025381 8542200.0 31262.0 51423.0 48553.0 52596.0 70250.0 54707.0 54053.0 36487.0 49657.0 31563.0 True False 36554.03914735501 56527.935597232434 49710.68765827788 49649.21663853267 56485.01679384455 51838.06861383061 48932.70853016905 35529.2549111721 50383.1396831856 37285.1220474295 0.9803921011940234 1.516098982466106 1.3332580109310659 1.3316093367047346 1.5149478851642577 1.390315111424033 1.3123923389045888 0.9529070299401515 1.3512934091805957 1.0 15.186312443533923 -7.603942754363312 7.906011210057401 1.115086689786489 1.358278341159573 0.2901127825231673 0.1702979969360175 0.30261273441554437 25.67652425917003 0.07631755143464919 0.043847919855521035 2.489185403529304e-08 7.603942754363312 0.24319165137308385 GS(ph)PSFLK ddPTM_PC-9_Lapatinib_30min_R1 2 GSPSFLK 7 0 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 GS(0.984)PS(0.016)FLK;GS(0.928)PS(0.072)FLK 87.639 0.017806 20893700.0 75332.0 108195.0 142212.0 126844.0 132995.0 115054.0 111819.0 102576.0 113808.0 84013.0 True False 74257.75186580302 107944.48112498104 130519.87831419538 136172.53089918007 125172.4955782303 110133.40862397359 117608.44068543108 107342.05543209863 100989.7445886302 98534.53510971436 0.7536215782935385 1.095498963939791 1.3246104847286952 1.381977707080642 1.2703413624355726 1.1177137893972335 1.193575841754149 1.0893851106373764 1.0249172483148377 1.0 16.58834183913597 -8.048431072154228 2.0360302386997438 1.004204735791963 1.1780257540148222 0.11562697470163763 0.16219397622110998 0.7561711747780718 5.653305929065588 0.15073284392918915 0.048894229370620414 8.94476485025184e-09 8.048431072154228 0.17382101822285922 GS(ph)PSGGSTAEASDTLSIR ddPTM_PC-9_AZD4547_30min_R2 3 GSPSGGSTAEASDTLSIR 18 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 GS(0.967)PS(0.033)GGSTAEASDTLSIR;GS(0.795)PS(0.205)GGSTAEASDTLSIR;GS(0.994)PS(0.006)GGSTAEASDTLSIR 220.97 4.6687e-28 51250000.0 19081.2 33144.2 31753.7 42171.1 31073.9 35214.6 39507.6 41154.8 24424.7 30476.5 True False 25148.624686384304 43857.414479843064 31332.625190501014 32449.20443200013 26759.825359557402 33012.62549517117 43023.6998636375 34795.271303222136 25715.73977798668 29409.52701132465 0.8551182981181706 1.4912655502060608 1.0653903130926192 1.1033568958625208 0.9099032891366483 1.1225146695646986 1.4629170964589289 1.183129238692741 0.8744016783433608 1.0 14.843995961329558 -8.255388736142066 24.658358996179366 0.9372008331224674 1.1578711343782562 0.15847591327644284 0.19458988807697453 664.6172154941878 2708568.759402992 0.13970038913385024 0.049654354410228106 5.554068910850101e-09 8.255388736142066 0.2206703012557888 GS(ph)PSGGSTAEASDTLSIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSPSGGSTAEASDTLSIR 18 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 GS(0.829)PS(0.08)GGS(0.049)T(0.042)AEASDTLSIR;GS(0.997)PS(0.003)GGSTAEASDTLSIR 229.69 2.8656999999999996e-35 29751000.0 24304.0 26551.0 25333.0 26814.0 37045.0 16461.199999999997 25239.0 15545.0 19823.8 19923.2 True False 28418.18717411925 29186.807810553993 25937.034795937514 25311.69851216093 29786.298179757592 15597.94569371357 22848.17920546385 15136.960221288964 20113.68557205498 23535.118448035573 1.2074800998714013 1.2401385561324911 1.1020566925637216 1.0754863447170644 1.2656107189570482 0.6627519520733705 0.9708121612352004 0.643164820041618 0.8546243613120131 1.0 14.522527493420615 -6.7559395605450545 24.999999865014164 0.8130022946538258 1.171666628205001 0.6848956838203111 0.11912904900735594 74.14453076321746 337031.4893886068 0.03785737780880316 0.03682730732145694 1.754124601093375e-07 6.7559395605450545 0.3586643335511752 GS(ph)PSGGSTAEASDTLSIR ddPTM_PC-9_Lapatinib_30min_R1 3 GSPSGGSTAEASDTLSIR 18 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 GS(0.972)PS(0.026)GGST(0.001)AEASDTLSIR;GS(0.824)PS(0.154)GGS(0.011)T(0.011)AEASDTLSIR;GS(0.841)PS(0.155)GGS(0.003)T(0.001)AEASDTLSIR 104.16 0.0003724 48896000.0 20219.5 32877.1 23579.0 30320.5 28982.699999999997 27165.5 36388.9 35675.0 28959.6 32043.8 True False 19931.16622219782 32800.97509491299 21640.425637572112 32550.370716222937 27277.99456818057 26003.69489087344 38272.93918974486 37332.590737990504 25697.864889892604 37582.52813432041 0.5303306406360846 0.8727719161862104 0.575810801237984 0.8661038075961126 0.725815849074567 0.69190914453482 1.0183705325239671 0.9933496385491517 0.6837715865747009 1.0 15.197774498041538 -7.249371816759287 24.758401252910474 0.9233187435549803 0.7194876663536017 0.3775361449390341 0.13394716692178962 720.9523899312039 1479143.6712860982 0.0490277680233151 0.037676077172923254 5.631553097443062e-08 7.249371816759287 -0.2038310772013786 GS(ph)PSPASVSSGR ddPTM_PC-9_Lapatinib_30min_R1 1 GSPSPASVSSGR 12 0 Q96II5;P10398 Q96II5 ARAF Serine/threonine-protein kinase A-Raf 1 GS(0.882)PS(0.112)PAS(0.006)VSSGR 67.749 0.036148 3375900.0 9401.0 10017.0 9470.0 8379.7 9980.0 9777.8 12198.0 9568.6 10668.0 7309.9 True False 9266.940016067745 9993.80625194265 8691.413155257129 8995.971091859737 9392.996021434932 9359.626287165054 12829.552754727607 10013.19208789169 9466.457500979783 8573.406475170503 1.080893579804689 1.1656750768653947 1.0137642698300129 1.0492878318452563 1.095596720934444 1.0917044834245906 1.4964358440117538 1.167936235951364 1.1041652496467596 1.0 13.065652829532526 -7.043934583886437 24.9998583689362 1.21869202827571 1.0815836912790147 0.14455573468135896 0.12392379220763215 721.858161941157 410752.8901659693 0.04673768408649658 0.03620514610830844 9.037855972313055e-08 7.043934583886437 -0.13710833699669545 GS(ph)PSPEKPDVEK ddPTM_PC-9_Lapatinib_30min_R1 1 GSPSPEKPDVEK 12 1 Q7Z3Z5;Q93074-3;Q93074;Q93074-2 Q7Z3Z5 TNRC11;MED12 Mediator of RNA polymerase II transcription subunit 12 1 GS(0.916)PS(0.084)PEKPDVEK 97.86 0.018529 2545400.0 13103.0 15958.0 16930.0 14187.0 12560.0 13317.0 11515.0 12653.0 14263.0 10595.0 True False 12916.148817204084 15921.050231456598 15538.080751689886 15230.359306444632 11821.245493910092 12747.46295344322 12111.190356672287 13240.904572047479 12656.550743951515 12426.331633049902 1.0394176816311125 1.2812349373576921 1.2504157470225379 1.2256520875345827 0.9513061330561561 1.0258428094369554 0.974639234998409 1.065552164794241 1.0185267155022089 1.0 13.601112841997525 -6.254319257468866 24.998864757967183 1.008681768008326 1.2087008710766627 0.6691274530565421 0.06640584916138041 325.1423470915803 1141578.9903739821 0.01950501689274414 0.02464417207663265 5.567763024575403e-07 6.254319257468866 0.2000191030683367 GS(ph)PSSHLLGADHGLR ddPTM_PC-9_AZD4547_30min_R2 2 GSPSSHLLGADHGLR 15 0 F8VU11;Q6NWY9-2;Q6NWY9-3;Q6NWY9 F8VU11 PRPF40B Pre-mRNA-processing factor 40 homolog B 1 GS(0.704)PS(0.148)S(0.148)HLLGADHGLR;GS(0.979)PS(0.015)S(0.006)HLLGADHGLR 67.153 0.017235 20434100.0 30670.3 27046.5 57254.0 72325.0 69184.0 56906.0 45738.5 69569.0 49961.0 41753.0 True False 40422.817418129496 35788.75220186565 56494.77455090095 55651.58866011111 59578.99580276763 53347.65882413007 49809.13789278474 58818.70958658198 52601.836462596955 40291.24017862409 1.0032656537481122 0.8882514423284701 1.4021602288845256 1.3812329532024736 1.4787084125143504 1.3240510490027773 1.2362274695930118 1.4598386479497685 1.3055402670505056 1.0 15.298178592383055 -5.26141773220948 24.999999993100673 1.344404849338188 0.945758520600581 0.5623625360221639 0.1322536736311069 1.1550482778684772 1331770.4003115196 0.03209899008638495 0.07463051232608017 5.47749850615834e-06 5.26141773220948 -0.39864632873760697 GS(ph)PSSHLLGADHGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSPSSHLLGADHGLR 15 0 F8VU11;Q6NWY9-2;Q6NWY9-3;Q6NWY9 F8VU11 PRPF40B Pre-mRNA-processing factor 40 homolog B 1 GS(0.973)PS(0.02)S(0.007)HLLGADHGLR 72.48899999999999 0.011072 4394100.0 7092.3 12946.0 21682.0 13909.0 21531.0 16267.0 15991.0 12422.0 13669.0 10424.0 True False 8292.88631068984 14231.193322866624 22198.9811094429 13129.723823586413 17312.155111576758 15413.929883583123 14476.21671518572 12095.935662196936 13868.883265792612 12313.788683661402 0.6734634257361659 1.1557119980261914 1.8027742459879714 1.0662619085714569 1.405916209569802 1.2517617671996562 1.1756102924190621 0.9823082052923708 1.12628888005806 1.0 13.587987095406932 -7.576127208434432 4.184478816872876 1.0418266163948746 1.2481126435443928 0.08741374724770612 0.2678181997458507 0.5372506924457123 19.7030995556792 0.1356937266981266 0.0764022223116248 2.6538281199848182e-08 7.576127208434432 0.20628602714951816 GS(ph)PTGGAQLLK ddPTM_PC-9_AZD4547_30min_R2 4 GSPTGGAQLLK 11 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 GS(0.998)PT(0.002)GGAQLLK;GS(1)PTGGAQLLK;GS(0.97)PT(0.03)GGAQLLK;GS(0.909)PT(0.091)GGAQLLK 148.13 0.00027484 86610000.0 115007.0 116207.0 141510.0 138393.0 116494.0 133861.0 107814.0 165101.0 111185.0 124078.0 True False 151576.83370579436 153768.64019825854 139633.4849390087 106488.63200053581 100320.81893281103 125490.65050885464 117409.23713660715 139588.4340935509 117062.01211132384 119734.06698640385 1.2659457539599515 1.2842513753059053 1.166196793055267 0.8893762208263409 0.8378636210879127 1.0480780755831542 0.9805833886018364 1.165820535515607 0.9776834200797386 1.0 16.869474163725705 -5.56867637819907 4.817902503108961 0.9893854794249244 1.265893352871798 0.6735305902468256 0.08288588034734402 0.12020370095128716 6.209842016516929 0.0249596582928139 0.04562821010280055 2.6997504473062e-06 5.56867637819907 0.27650787344687355 GS(ph)PTGGAQLLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GSPTGGAQLLK 11 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 GS(0.998)PT(0.002)GGAQLLK;GS(0.999)PT(0.001)GGAQLLK;GS(0.998)PT(0.002)GGAQLLK;GS(1)PTGGAQLLK 155.88 0.00022343 72406000.0 267559.0 310086.0 288164.0 252111.0 302146.0 249147.0 268234.0 228898.0 238781.0 187228.0 True False 312851.45416886796 340869.28879301925 295034.92262805504 237986.03802488983 242942.66027320886 236081.2927217732 242824.93367401228 222889.67003747795 242272.72039572947 221170.95430396698 1.4145232368030551 1.5412027762223448 1.3339677606245388 1.0760275406589466 1.0984383597645462 1.067415445507886 1.0979060719713 1.0077709830340056 1.0954093007292505 1.0 17.754802407780353 -5.637671099909471 2.913145439451763 1.0640399982173825 1.4759758574744197 0.936853845625882 0.04458640701581656 0.05209285195150362 0.8828020417053528 0.011943349272720533 0.02320808444030681 2.3031854064955427e-06 5.637671099909471 0.41193585925703724 GS(ph)PTGGAQLLK ddPTM_PC-9_Lapatinib_30min_R1 2 GSPTGGAQLLK 11 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 GS(1)PTGGAQLLK;GS(0.999)PT(0.001)GGAQLLK 165.35 0.00032819 62078000.0 78977.0 134229.0 142004.0 132995.0 149628.0 142934.0 147988.0 139930.0 125872.0 129612.0 True False 77850.77349739202 133918.20099750522 130328.9792712921 142775.8959583141 140827.17521996642 136821.04601542788 155650.09452915474 146431.65863957955 111694.9698690785 152015.26150286561 0.5121247217400239 0.8809523443472204 0.857341414163441 0.9392208028772339 0.9264015588152753 0.900048091637488 1.023910974400558 0.9632694585524835 0.7347615546283355 1.0 17.213856644087485 -4.472458770476433 1.8458720106609514 0.9227871786103043 3.0521068714668085e-14 0.7105576697983416 0.07696632073482156 1.2819849804899925 2.177922283685978 0.02041487323778785 2.7071932783844814 3.369312006137005e-05 4.472458770476433 -0.9227871786102738 GS(ph)PTPGFSTR ddPTM_PC-9_AZD4547_30min_R2 1 GSPTPGFSTR 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 GS(0.984)PT(0.016)PGFSTR 106.16 0.0075439999999999995 0.0 44054.0 37102.0 51497.0 57783.0 56643.0 52245.0 50481.0 64865.0 30234.0 59286.0 True False 58062.25561987577 49094.495930845726 50814.11613245794 44462.02208845073 48779.0971793502 48978.11189095486 54973.71120534491 54841.60469941552 31832.10751606568 57210.41518525394 1.0148896041369997 0.8581391302942317 0.8881969474948914 0.7771665691374124 0.8526261699272386 0.8561048146977795 0.9609039023285126 0.9585947684845855 0.556404064067524 1.0 15.803990193830966 -4.7612585055810595 8.264343794770024 0.8567068923100828 1.0165857498749986 0.13955734104338502 0.11802042994898264 0.18376346368820523 123.86323018969044 0.028061017594185805 0.1636071423232263 1.732772290780371e-05 4.7612585055810595 0.15987885756491582 GS(ph)PTPGFSTR ddPTM_PC-9_Lapatinib_30min_R1 1 GSPTPGFSTR 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 GS(0.718)PT(0.279)PGFS(0.003)TR 106.16 0.0075439999999999995 0.0 42634.0 40887.0 45968.0 46270.0 53577.0 54915.0 43393.0 27430.0 56645.0 38657.0 True False 42026.03134188195 40792.32866358979 42188.68848161141 49672.85015219519 50425.706196434796 52566.41346311737 45639.67721642034 28704.497938138185 50265.043601706064 45338.81094278531 0.9269328080728919 0.8997220662682819 0.9305203997266458 1.0955922557139657 1.1121973679474926 1.159413146706755 1.0066359542162389 0.6331109559613601 1.1086537682943944 1.0 15.468458934954539 -5.552821124540118 22.753611783582 1.0109339861162603 0.9137758251624554 0.0938924053581941 0.13866340313172468 201.7539373245952 153313.63796448155 0.040666213494921756 0.07043844871589933 2.8001343902179294e-06 5.552821124540118 -0.09715816095380492 GS(ph)PTSAYPER ddPTM_PC-9_AZD4547_30min_R2 5 GSPTSAYPER 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 GS(0.954)PT(0.035)S(0.011)AYPER;GS(0.999)PTSAYPER;GS(0.974)PT(0.021)S(0.005)AYPER;GS(0.631)PT(0.105)S(0.263)AYPER;GS(0.999)PT(0.001)SAYPER 118.77 0.00084579 880832200.0 61156.0 64738.3 79063.0 91057.0 81061.0 89397.0 86637.0 101989.0 77400.2 84716.0 True False 80602.33587617765 85663.68944854365 78014.5729611535 70065.21546662602 69807.07936471069 83806.99145785617 94347.5251618919 86228.94352406843 81491.41655635998 81750.1186255434 0.9859598644177732 1.0478723565029473 0.9543053181182456 0.8570656121926855 0.8539079886166547 1.0251604874328597 1.1540964924350867 1.054786769411801 0.996835453287005 1.0 16.31893320362022 -6.984775202238682 24.24266750222181 1.0607999950220088 0.9417822157280943 0.38852239332694005 0.06692599698256531 181.15990467039202 288461.95611599955 0.026088629133765095 0.022999088071546925 1.035678111495166e-07 6.984775202238682 -0.11901777929391455 GS(ph)PTSAYPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GSPTSAYPER 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 GS(0.997)PT(0.002)S(0.001)AYPER;GS(0.997)PT(0.003)SAYPER;GS(0.998)PT(0.001)SAYPER;GS(0.997)PT(0.002)S(0.001)AYPER;GS(0.975)PT(0.019)S(0.006)AYPER 126.66 0.00033883 955982200.0 117144.4 151913.0 177201.0 126784.0 149818.0 106813.0 120492.0 111999.8 105026.0 104837.7 True False 136974.63321263547 166993.91868195884 181426.1438785344 119680.70351927372 120462.23837751149 101211.53824646004 109078.12547346347 109059.92392359751 106561.80656032903 123843.94511522316 1.1060260805257427 1.3484221495575692 1.4649577232842295 0.9663831639724009 0.9726938064306223 0.8172505983420816 0.8807707584894706 0.8806237868321237 0.8604522930950318 1.0 16.91816380958727 -5.872521361380398 5.80704049267855 0.8978791239226088 1.308598937449815 0.7806930811052498 0.09633633704287765 0.09047650204740018 4.26641447895214 0.027831172401402118 0.041887921032312696 1.341153967252791e-06 5.872521361380398 0.4107198135272062 GS(ph)PTSAYPER ddPTM_PC-9_Lapatinib_30min_R1 5 GSPTSAYPER 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 GS(0.997)PT(0.002)S(0.001)AYPER;GS(0.803)PT(0.152)S(0.045)AYPER;GS(0.996)PT(0.003)S(0.001)AYPER;GS(0.982)PT(0.014)S(0.004)AYPER;GS(0.975)PT(0.02)S(0.006)AYPER 102.05 0.0033668 778674900.0 37335.8 56098.5 54186.0 55621.5 60565.5 54778.0 48777.0 53066.5 63682.3 48807.9 True False 36803.38464545284 55968.60736993158 49731.03624400875 59712.09065788473 57003.1563663544 52435.27263375478 51302.434392306044 55532.1633187827 56509.72876965175 57244.280482561255 0.6429181105117484 0.977715273877566 0.8687511804634994 1.043110161478495 0.9957878042282267 0.915991470095052 0.8962019254995209 0.9700910353078832 0.9871681204354857 1.0 15.804843934214865 -4.759256552287493 24.999893580564635 0.9579495304901509 0.6429177055719218 0.7825349845625797 0.05037235342874744 26.86969451287971 307665.53009544814 0.01274307191983963 0.08210037679093002 1.7407782336243122e-05 4.759256552287493 -0.315031824918229 GS(ph)PTSAYPERR ddPTM_PC-9_AZD4547_30min_R2 4 GSPTSAYPERR 11 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 GS(0.568)PT(0.376)S(0.056)AYPERR;GS(0.927)PT(0.065)S(0.007)AYPERR;GS(0.744)PT(0.1)S(0.1)AY(0.055)PERR;GS(0.751)PT(0.104)S(0.145)AYPERR 95.477 0.0091117 43063600.0 49652.6 39709.1 78873.0 118130.0 95824.0 69675.3 47371.3 87847.0 50985.1 59390.0 True False 65441.0939617616 52544.29002122652 77827.09248529737 90896.95359030651 82520.49164264012 65318.492476521176 51587.25392963203 74272.26467323744 53680.068297855374 57310.77417690907 1.141863722862224 0.9168309236066297 1.3579836183168237 1.5860360446313697 1.439877454593664 1.1397244831293603 0.9001318629964854 1.2959564015654543 0.9366488076422368 1.0 15.806518764437676 -6.989838014235208 22.749847192234853 1.05243027448117 1.28841153355806 0.2784121749924967 0.1935368241318998 112.91449603328788 252779.81309653728 0.07538832480732414 0.06637693187785229 1.0236747374366043e-07 6.989838014235208 0.23598125907688994 GS(ph)PTSAYPERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GSPTSAYPERR 11 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 GS(0.931)PT(0.013)S(0.056)AYPERR;GS(0.959)PT(0.015)S(0.026)AY(0.001)PERR;GS(0.999)PT(0.001)SAYPERR;GS(0.834)PT(0.133)S(0.033)AY(0.001)PERR 89.805 0.013341999999999998 35085800.0 78244.9 46330.4 82855.0 84896.0 93309.0 94668.0 85473.5 90690.0 96079.0 71786.4 True False 91490.21616278146 50929.77592505332 84830.57742933724 80139.5523565454 75025.771274261 89703.4434265107 77376.83130544864 88309.48359399788 97483.97361138987 84800.7060591701 1.0788850755434007 0.6005819797009334 1.0003522537907443 0.9450340224835823 0.8847305023841595 1.0578148177671975 0.912455036063716 1.041376749061258 1.1495655890337748 1.0 16.371788656411304 -6.774215103600321 0.6581744205326471 1.0622641487575541 0.8623099129058434 0.18984127242026083 0.12928634820419801 1.1608587010159215 1.1011150267371366 0.09660888741819068 0.10110429929425792 1.6818408484857566e-07 6.774215103600321 -0.1999542358517108 GS(ph)PTSAYPERR ddPTM_PC-9_Lapatinib_30min_R1 2 GSPTSAYPERR 11 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 GS(0.911)PT(0.044)S(0.044)AYPERR;GS(0.934)PT(0.058)S(0.008)AYPERR 111.52 0.0026460999999999998 16722000.0 46773.0 35503.0 44649.0 33950.0 36039.0 40581.0 34501.0 27047.0 44350.0 30070.0 True False 46106.00844288231 35420.794984797816 40978.131570124155 36446.79625387998 33919.25687540015 38845.445228931356 36287.29296531049 28303.702359927953 39354.835973795816 35267.55943424358 1.3073206420434915 1.0043449434271159 1.161921386891768 1.0334368705562142 0.9617693262456296 1.1014497700460035 1.0289142074877113 0.8025421325992305 1.1158933763810044 1.0 15.106054122199359 -1.5228787452803392 0.6387222418902812 0.9978763894694905 22.764167325127772 0.41532803100669247 0.09672653967963131 209.38647624208954 1.410055912092532 0.040372427613186275 6427.311580048892 0.029999999999999888 1.5228787452803392 21.766290935658283 GS(ph)PTTGFIEQK ddPTM_PC-9_AZD4547_30min_R2 1 GSPTTGFIEQK 11 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 GS(0.962)PT(0.032)T(0.006)GFIEQK 95.477 0.0062026 8961800.0 23607.0 22459.0 23589.0 26550.0 20723.0 29478.0 30243.0 22443.0 26521.0 23346.0 True False 31113.53494389631 29718.43254031763 23276.194447221194 20429.30769341097 17845.96915501782 27634.736000030003 32934.568411545835 18974.950038834228 27922.845916305403 22528.66364596935 1.3810643823724047 1.3191387206686187 1.033181320161686 0.9068140043480128 0.7921450395576695 1.2266478133945682 1.4618962282495715 0.8422581266700688 1.2394364066641448 1.0 14.459474117955777 -5.205677412722301 4.937510201829254 1.0619049253483361 1.3608588501322314 0.26435839963035734 0.1922380943143866 0.29778271230003717 15.63602390759546 0.05210874156759833 0.1440401739827511 6.22762691986001e-06 5.205677412722301 0.29895392478389526 GS(ph)PTTGFIEQK ddPTM_PC-9_Lapatinib_30min_R1 1 GSPTTGFIEQK 11 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 GS(0.997)PT(0.003)TGFIEQK 155.88 0.00069335 10348000.0 14196.0 21168.0 20052.0 21271.0 24176.0 23262.0 23689.0 21992.0 20605.0 18753.0 True False 13993.562436772441 21118.986796558052 18403.401962958393 22835.340297975883 22754.01521184476 22267.13848637052 24915.500508832796 23013.828605743172 18284.24791973084 21994.43106319819 0.6362320714986319 0.9601970033175825 0.836730075448579 1.0382328250438235 1.0345352942508037 1.0123989305469525 1.1328095024254679 1.0463479841608938 0.8313126112329702 1.0 14.424850662637976 -4.2178543777185835 0.9510901673352778 1.01618591771248 2.7173119471029023e-14 0.5878247544098478 0.08835852117259253 3.7127255278884554 1.2608323085756699 0.029151348995218974 5.022516302967712 6.055438842403712e-05 4.2178543777185835 -1.0161859177124528 GS(ph)PVFLPR ddPTM_PC-9_AZD4547_30min_R2 2 GSPVFLPR 8 0 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 GS(1)PVFLPR;GS(1)PVFLPR 105.4 0.0038428000000000004 24065000.0 26718.0 26971.0 32050.0 37514.0 33859.0 32987.0 28531.0 37113.0 30024.0 30397.0 True False 35213.76823107646 35688.84830334861 31624.996058901997 28865.726885522392 29158.262298882786 30924.317675316815 31070.20372812932 31378.038621897897 31611.00734478919 29332.81028212671 1.2004907778145342 1.2166869781684304 1.0781440903455466 0.9840764184504707 0.9940493944642501 1.0542569013293572 1.0592303781769337 1.069724936686936 1.077667193860748 1.0 14.840227677233576 -5.348739523180695 3.858781472793249 1.0369847059037016 1.2098921442141646 0.8245653864773426 0.03161338770349444 0.09297058674071058 2.5467131152156015 0.009335673462786697 0.02168832051499982 4.479819097459896e-06 5.348739523180695 0.17290743831046296 GS(ph)PVFLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GSPVFLPR 8 0 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 GS(1)PVFLPR;GS(1)PVFLPR;GS(1)PVFLPR;GS(1)PVFLPR 111.65 0.0037426 18691600.0 37240.5 55996.8 50848.0 49244.4 46680.1 32617.4 44203.8 32593.4 40243.5 32784.0 True False 43544.5811165976 61555.792234041226 52060.40916211387 46485.39592049888 37533.46950090166 30906.88612434897 40016.49605620204 31737.857785561897 40831.985054277924 38727.479681998775 1.1243845836122897 1.5894603196358645 1.3442756820117185 1.200320710312221 0.9691689159506005 0.7980608699077065 1.033284282498828 0.8195177699703041 1.0543413976215281 1.0 15.241069995850044 -6.082859373855459 2.3761101531667475 0.9305758952346121 1.375968093087675 0.666977156876903 0.13069833922961654 0.1598848970928393 1.7797407818830921 0.039630339086460756 0.05718997204422254 8.263054670011662e-07 6.082859373855459 0.44539219785306283 GS(ph)PVFLPR ddPTM_PC-9_Lapatinib_30min_R1 4 GSPVFLPR 8 0 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 GS(1)PVFLPR;GS(1)PVFLPR;GS(1)PVFLPR;GS(1)PVFLPR 101.46 0.0045792 22284500.0 35262.4 38423.1 43360.8 39241.1 43683.3 42831.6 45938.2 41958.9 37581.5 34855.4 True False 34759.55170966784 38334.13367265824 39795.842401528345 42127.02139847218 41113.93417867219 40999.79231333622 48316.6552186611 43908.463672495316 33348.675719260595 40880.1094480989 0.8502802996111917 0.9377209158729622 0.9734769045090955 1.030501678376286 1.0057197677239627 1.0029276552057491 1.1819111022685393 1.0740789167465707 0.8157677699371094 1.0 15.31911143834989 -4.76605009910701 1.0235811863568534 1.026464712010462 0.756630405011596 0.26112771109468746 0.08546721582034467 2.6251558158687174 2.163704710476956 0.02881100772379936 0.7877181192245527 1.7137596011557418e-05 4.76605009910701 -0.269834306998866 GS(ph)PVPPVPER ddPTM_PC-9_AZD4547_30min_R2 4 GSPVPPVPER 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 GS(1)PVPPVPER;GS(1)PVPPVPER;GS(1)PVPPVPER;GS(1)PVPPVPER 93.258 0.0069088000000000005 58600000.0 169934.0 157511.0 240531.0 300458.0 246501.0 255958.0 210705.0 286423.0 202162.0 225113.0 True False 223969.4771532208 208423.35045451546 237341.40177983665 231192.05012982574 212278.59106698062 239952.90579739749 229457.33681032885 242162.90669576277 212847.87059809713 217231.86238906404 1.031015775909013 0.9594511052031011 1.092571776394184 1.064263996944237 0.977198228346392 1.1045935120127077 1.0562784588172838 1.1147669777007527 0.9798188362298568 1.0 17.728876199767768 -6.765900804827915 24.999953055921114 1.058588661432261 1.0272105324945768 0.04840134568893417 0.05259963088987951 327.90465710806416 1837422.8182132826 0.017971438102275424 0.01635909587980824 1.714348829194612e-07 6.765900804827915 -0.03137812893768421 GS(ph)PVPPVPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GSPVPPVPER 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 GS(1)PVPPVPER;GS(1)PVPPVPER;GS(1)PVPPVPER 92.611 0.007321899999999999 35456600.0 90023.0 113792.0 125668.0 122285.0 137832.0 112406.0 105998.0 111644.0 96549.0 85951.0 True False 105262.11586470273 125088.51773487106 128664.40171854376 115433.76790331921 110824.80903529072 106511.23148054624 95957.10208093644 108713.46329659602 97960.84647223749 101533.23591225821 1.036725707783675 1.2319957756785036 1.267214627432257 1.1369062245103012 1.0915126267723998 1.0490282371438437 0.9450807040549708 1.070718000069876 0.9648155659777468 1.0 16.631592531276553 -6.533946745290174 1.7042206747091793 1.0018625151572487 1.182798579317313 0.585957183196474 0.06508448688694286 0.25466473884074287 1.5019031379703984 0.025549457993846558 0.027708260390451076 2.9245109696307393e-07 6.533946745290174 0.18093606416006436 GS(ph)PVPPVPER ddPTM_PC-9_Lapatinib_30min_R1 3 GSPVPPVPER 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 GS(1)PVPPVPER;GS(1)PVPPVPER;GS(1)PVPPVPER 121.29 0.00063498 34804900.0 135494.0 166470.0 171353.0 139090.0 172364.0 145011.0 139636.0 136838.0 158617.0 122784.0 True False 133561.8307134433 166084.5489428866 157265.01778170833 149319.1425906379 162225.88840066243 138809.21756715127 146865.66883580454 143195.9930316786 140751.88314894197 144007.05080060422 0.9274673008780409 1.1533084527427164 1.092064707300071 1.0368877201532927 1.1265135109619353 0.9639057031960886 1.019850542173511 0.9943679301505269 0.9773957758764921 1.0 17.13577992434079 -6.773363221706751 24.99571402990424 0.9925486418002254 1.071721447209853 0.29760572861174994 0.0582660908119208 273.27734536787005 572862.5108466888 0.019599905319706106 0.017418267645943713 1.6851430683325802e-07 6.773363221706751 0.07917280540962768 GS(ph)SDGRGSDSESDLPHR ddPTM_PC-9_Lapatinib_30min_R1 1 GSSDGRGSDSESDLPHR 17 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 GS(0.381)S(0.381)DGRGS(0.123)DS(0.046)ES(0.068)DLPHR 47.855 0.046316 23749000.0 29531.0 19156.0 37153.0 26917.0 32218.0 32640.0 25576.0 28198.0 38837.0 26619.0 True False 29109.882524677865 19111.64545894112 34098.42375472737 28896.565972479755 30323.000583025085 31244.06328755627 26900.200135670893 29508.182021860004 34462.76808825947 31220.058682412047 0.9324096030952382 0.6121591779616912 1.0921960173616478 0.9255769268863917 0.9712666107225377 1.0007688840494635 0.8616319530118384 0.9451674105431315 1.1038662175120837 1.0 14.930185628612398 -5.269436659055124 24.999767916416037 0.9787797783664839 0.7722843856065604 0.42752274500104337 0.09922916688512858 485.9664364275366 1519150.7228431401 0.024537428667856787 0.05255459853533262 5.37728854035789e-06 5.269436659055124 -0.20649539275992346 GS(ph)SFQSGRDDTWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSSFQSGRDDTWR 13 1 Q96KP1 Q96KP1 EXOC2 Exocyst complex component 2 1 GS(0.489)S(0.489)FQS(0.021)GRDDTWR 54.005 0.039346 4009000.0 8315.4 6988.5 7214.3 12959.0 12073.0 14040.0 12083.0 15994.0 11466.0 8169.7 True False 9723.032983363693 7682.272094612502 7386.31627238511 12232.949243644864 9707.38231675566 13303.717683992567 10938.410766655565 15574.174447043793 11633.668558459145 9650.801938690385 1.0074844603725346 0.7960242209317361 0.7653577722668956 1.2675577968917344 1.005862764402867 1.3785090367109827 1.1334198791090213 1.6137699795295157 1.205461331852577 1.0 13.236433113561102 -6.025146160471246 1.3850111824392306 1.2818962585617726 0.8500721468856598 0.39617355824158784 0.1920210953753013 0.3804341530674577 1.4782855249820763 0.066737236615889 0.11744747874522643 9.437432089615458e-07 6.025146160471246 -0.4318241116761128 GS(ph)SGNASEVSVACLTER ddPTM_PC-9_AZD4547_30min_R2 1 GSSGNASEVSVACLTER 17 0 Q69YQ0-2;Q69YQ0;F8WAN1;A0A494C1J1;C9J8U1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 GS(0.964)S(0.036)GNASEVSVACLTER 99.37100000000001 0.0012642999999999999 3888900.0 7353.9 3243.6 11041.0 10376.0 12680.0 8011.8 7791.2 9357.9 6318.6 6657.6 True False 9692.287229377687 4292.030267944886 10894.58912593876 7983.973507601969 10919.60087273203 7510.820879470802 8484.601706445654 7911.851578149386 6652.588296322437 6424.519450415731 1.508640032018348 0.6680702426182473 1.6957827289687437 1.2427347398077107 1.6996758990317045 1.169086799011057 1.3206593538909148 1.231508697142696 1.0354997517973032 1.0 12.649372830419162 -8.177100299996814 1.9225573397645 0.9922132781489373 1.3250330859639576 0.1640534371457305 0.2782840132513867 0.6420454585426031 4.246671055453564 0.24656649627175636 0.07464042922680879 6.651195295876423e-09 8.177100299996814 0.3328198078150203 GS(ph)SGNASEVSVACLTER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSSGNASEVSVACLTER 17 0 Q69YQ0-2;Q69YQ0;F8WAN1;A0A494C1J1;C9J8U1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 GS(0.916)S(0.084)GNASEVSVACLTER;GS(0.968)S(0.032)GNASEVSVACLTER 79.695 0.0062233 6063000.0 6991.7 7772.3 12906.9 11096.8 9950.6 7024.4 12853.400000000001 9664.7 12419.7 6389.8 True False 8175.2567176304065 8543.882578658762 13214.64944569083 10475.082272311001 8000.851360979783 6656.028098250531 11635.832901442574 9411.011865596105 12601.314616736006 7548.22015837103 1.0830707830592339 1.1319069130732144 1.750697405273174 1.387755265815089 1.0599652889173856 0.8818010019049256 1.541533322731499 1.2467855558186423 1.6694418488524156 1.0 12.88192078719213 -9.457147091349693 11.831555892402024 0.9999890331542758 1.3017465838021203 0.1050413527268591 0.2676097237026573 0.0 0.0 0.267468141185421 0.06487055279971225 3.490220850461311e-10 9.457147091349693 0.3017575506478445 GS(ph)SGNASEVSVACLTER ddPTM_PC-9_Lapatinib_30min_R1 2 GSSGNASEVSVACLTER 17 0 Q69YQ0-2;Q69YQ0;F8WAN1;A0A494C1J1;C9J8U1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 GS(0.942)S(0.058)GNASEVSVACLTER;GS(0.888)S(0.112)GNASEVSVACLTER 89.913 0.002475 7411800.0 20057.6 27871.0 31752.0 28517.2 32838.0 27029.6 26971.7 28632.4 33083.0 25057.3 True False 19771.574945886652 27806.46641188914 29141.47312626448 30614.450018590484 30906.533401991986 25873.607017075086 28368.162652458333 29962.765831715205 29356.84416056565 29388.420918246484 0.672767516189038 0.9461708231701844 0.9915971057897608 1.0417181006000493 1.0516568238888584 0.8804014032959102 0.965283664997642 1.019543238306898 0.9989255374499817 1.0 14.842960222559874 -4.748646640542481 3.1970847649922094 0.9924161314735107 0.6116812735532007 0.8201014474027197 0.04482575320273406 0.1689270140453659 2.458811474163829 0.012256083073855577 0.1694422159469478 1.7838295726360915e-05 4.748646640542481 -0.38073485792031003 GS(ph)SGSPAHAESYSSGGGGQQK ddPTM_PC-9_AZD4547_30min_R2 1 GSSGSPAHAESYSSGGGGQQK 21 0 P15408 P15408 FOSL2 Fos-related antigen 2 1 GS(0.333)S(0.333)GS(0.333)PAHAESYSSGGGGQQK 105.99 4.4568000000000004e-05 7776300.0 6506.4 3671.8 14236.0 28171.0 23109.0 16350.0 11571.0 19647.0 14317.0 20915.0 True False 8575.299858472785 4858.6375440374995 14047.22133836284 21676.611187611332 19900.714240375743 15327.631915343309 12600.79658400281 16611.00759314602 15073.7673912652 20182.77221603055 0.4248821602248323 0.24073192186048825 0.6960005884229109 1.0740155492808998 0.9860248149939097 0.7594413567809603 0.6243342811942548 0.8230290376042798 0.7468630785662128 1.0 14.300836729793163 -5.406105743526703 4.444453748481612 0.8457633903098672 0.3384063744508726 0.7012469892674797 0.13508840964805122 0.12796922343214162 4.0313991770421 0.03880817883825354 0.08452665628760425 3.925493444868074e-06 5.406105743526703 -0.5073570158589946 down GS(ph)SGSPAHAESYSSGGGGQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSSGSPAHAESYSSGGGGQQK 21 0 P15408 P15408 FOSL2 Fos-related antigen 2 1 GS(0.333)S(0.333)GS(0.333)PAHAESYSSGGGGQQK 67.877 0.0020065 5050000.0 3889.1 5775.9 11040.0 10744.0 14633.0 13932.0 10713.0 11182.0 12576.0 8696.1 True False 4547.447816773662 6349.293180406719 11303.235469433155 10142.048512517978 11765.76869386943 13201.3813941157 9698.18708459663 10888.484348308335 12759.900208545458 10272.634091710272 0.44267592675605233 0.6180783938883233 1.1003249379391942 0.9872880141523125 1.1453507044862112 1.28510188100332 0.9440798726027626 1.059950568773304 1.2421254465631497 1.0 13.326518542100073 -5.16111764209434 2.7338849309969566 1.1015183893631597 0.4521201996022851 0.8281135389049148 0.10417675749129848 0.10947889855661144 1.5232852440750193 0.02817464091356162 0.10602808111913145 6.900528563597628e-06 5.16111764209434 -0.6493981897608746 down GS(ph)SGSPAHAESYSSGGGGQQK ddPTM_PC-9_Lapatinib_30min_R1 2 GSSGSPAHAESYSSGGGGQQK 21 0 P15408 P15408 FOSL2 Fos-related antigen 2 1 GS(0.333)S(0.333)GS(0.333)PAHAESYSSGGGGQQK;GS(0.333)S(0.333)GS(0.333)PAHAESYSSGGGGQQK 104.16 5.4607e-05 10450800.0 29459.0 18999.6 43326.0 26410.0 40138.0 43666.0 32950.0 33460.0 51622.0 31695.7 True False 29038.90925788105 18955.607593531942 39763.90352319645 28352.279501177338 37777.161754344204 41798.506970417606 34655.989774411784 35014.67375173545 45807.786756240996 37174.259513134515 0.7811563602933621 0.5099121769146334 1.0696622890133685 0.7626857904502397 1.016218271704825 1.124393801459562 0.9322577027302194 0.9419064215485977 1.232244767109781 1.0 15.18201638457446 -5.50209059787235 0.918076327652028 1.0384040398001313 0.6155784849425682 0.4483571759527408 0.14615926851498023 0.8088663946359915 1.0672236361014449 0.05530173983963741 0.27565932602897203 3.147091732983268e-06 5.50209059787235 -0.4228255548575631 GS(ph)SLSGTDDGAQEVVK ddPTM_PC-9_Lapatinib_30min_R1 1 GSSLSGTDDGAQEVVK 16 0 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 1 GS(0.881)S(0.116)LS(0.002)GTDDGAQEVVK 138.81 1.6693e-05 3058100.0 17489.0 19811.0 20590.0 19948.0 25227.0 24829.0 25338.0 30465.0 24649.0 22738.0 True False 17239.603652910202 19765.128846684212 18897.169679698447 21415.04246457725 23743.19745819028 23767.12154922594 26649.87766021383 31880.51511795042 21872.77005452295 26668.233003519457 0.6464471662083895 0.7411487984252939 0.7086022413710181 0.8030169251090264 0.8903176095340417 0.891214710254307 0.9993117150542669 1.195449099073909 0.8201807015724049 1.0 14.702834616830033 -6.357620793731598 0.9071580850629306 1.01755210519188 0.6810678248028851 0.6626844573070999 0.08997466737536845 0.3421537221895217 0.6086463571589202 0.0453281312573467 0.06556664553306168 4.389137701315667e-07 6.357620793731598 -0.336484280388995 GS(ph)SPLGPAGLGAEEPAAGPQLPSWLQPER ddPTM_PC-9_AZD4547_30min_R2 1 GSSPLGPAGLGAEEPAAGPQLPSWLQPER 29 0 H0YKL4;O43482 H0YKL4 OIP5 Protein yippee-like;Protein Mis18-beta 1 GS(0.5)S(0.5)PLGPAGLGAEEPAAGPQLPSWLQPER 57.397 0.0010872 7467800.0 10548.0 8193.0 12686.0 16366.0 16891.0 12529.0 7510.7 16007.0 12052.0 15928.0 True False 13902.044587970446 10841.227027152685 12517.775351114846 12593.071552179441 14545.976209883032 11745.559649378378 8179.137749846156 13533.485954267233 12689.044115354345 15370.365568105875 0.9044706533732513 0.7053330631021988 0.8144097351262569 0.8193085256417433 0.9463650129484569 0.7641691797982271 0.5321368391405208 0.8804921323634461 0.8255525256786749 1.0 13.907863857982267 -8.75801689398039 1.830763868961407 0.9990536667994148 0.7898706079393638 0.2349597881431148 0.11006549767994946 1.3617391452747474 7.765148095238681 0.10863837767504612 0.030484215116051344 1.7457542420609413e-09 8.75801689398039 -0.20918305886005095 GS(ph)SPLGPAGLGAEEPAAGPQLPSWLQPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSSPLGPAGLGAEEPAAGPQLPSWLQPER 29 0 H0YKL4;O43482 H0YKL4 OIP5 Protein yippee-like;Protein Mis18-beta 1 GS(0.5)S(0.5)PLGPAGLGAEEPAAGPQLPSWLQPER;GS(0.5)S(0.5)PLGPAGLGAEEPAAGPQLPSWLQPER 164.15 9.4916e-15 11220100.0 22208.1 27685.0 29756.0 26689.7 36968.0 29086.0 27783.0 33816.0 31060.0 21983.3 True False 25967.492700031158 30433.383836209083 30465.495890258433 25194.362638174873 29724.385777008476 27560.678957023345 25151.19310849884 32928.36583101365 31514.193740253017 25968.698270292938 0.9999535760225934 1.1719256590933382 1.1731622268147972 0.9701819619890663 1.1446236337156677 1.0613038308720912 0.9685195941173036 1.2680021727805384 1.2135453772938587 1.0 14.664486077583433 -7.7684127422882705 24.99976791605474 1.1805802911225276 1.0765464898458565 0.14387902392192709 0.09668861870706202 275.74739642754906 988543.4822622791 0.05019266583866187 0.02493187847465428 1.7044617424812578e-08 7.7684127422882705 -0.10403380127667106 GS(ph)SPLGPAGLGAEEPAAGPQLPSWLQPER ddPTM_PC-9_Lapatinib_30min_R1 2 GSSPLGPAGLGAEEPAAGPQLPSWLQPER 29 0 H0YKL4;O43482 H0YKL4 OIP5 Protein yippee-like;Protein Mis18-beta 1 GS(0.5)S(0.5)PLGPAGLGAEEPAAGPQLPSWLQPER;GS(0.5)S(0.5)PLGPAGLGAEEPAAGPQLPSWLQPER 252.31 1.4924999999999997e-80 11602200.0 37407.0 31452.0 38585.0 32530.0 32090.0 36797.0 27994.5 28512.0 33433.0 29623.4 True False 36873.56932039634 31379.17482640511 35412.69024240723 34922.36471689883 30202.529291367424 35223.27808799657 29443.918231859505 29836.77160817339 29667.423474902243 34743.76521930066 1.0613003250411255 0.9031598800055651 1.0192530953074417 1.005140476182442 0.869293500595885 1.0138014076962947 0.8474590490124251 0.8587662108538149 0.8538920087573458 1.0 15.084466488487307 -6.66747009528547 1.076595693871317 0.8859097541757495 0.9912200386722663 0.2484290051660204 0.06887384165829688 0.6597515363960125 1.6361571845562772 0.03473693578509059 0.03454469775432079 2.150452750440062e-07 6.66747009528547 0.1053102844965168 GS(ph)SPLPTATTPKPLIPTEASIR ddPTM_PC-9_AZD4547_30min_R2 1 GSSPLPTATTPKPLIPTEASIR 22 1 A0A3B3IUD2;Q9BUK6-7;Q9BUK6-3;Q9BUK6-2;Q9BUK6 A0A3B3IUD2 MSTO1 Protein misato homolog 1 1 GS(0.288)S(0.288)PLPT(0.143)AT(0.206)T(0.075)PKPLIPTEASIR 62.582 0.0023535 8124400.0 12812.0 12830.0 14450.0 15791.0 15772.0 15465.0 15613.0 17101.0 15879.0 15679.0 True False 16885.949493845023 16977.04659567546 14258.383558537726 12150.628918517992 13582.330044537031 14497.971105246756 17002.52675361125 14458.43339188629 16718.331522379012 15130.082982316178 1.1160513470799251 1.1220722725392838 0.9423863421768881 0.8030774803231067 0.897703605486623 0.9582215194848418 1.1237563451227306 0.9556083339916309 1.1049728902292972 1.0 13.885132279717961 -9.594956728557333 14.286610775821304 1.0000017278016433 0.9963051855420638 0.0 0.10549029821181641 0.0 0.0 0.11145374973297564 0.027031504854130285 2.5412258909732184e-10 9.594956728557333 -0.003696542259579494 GS(ph)SPLPTATTPKPLIPTEASIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSSPLPTATTPKPLIPTEASIR 22 1 A0A3B3IUD2;Q9BUK6-7;Q9BUK6-3;Q9BUK6-2;Q9BUK6 A0A3B3IUD2 MSTO1 Protein misato homolog 1 1 GS(0.533)S(0.449)PLPT(0.018)AT(0.001)TPKPLIPTEASIR;GS(0.533)S(0.465)PLPT(0.002)AT(0.001)TPKPLIPTEASIR 72.899 0.000586 9255100.0 26065.0 24438.9 26788.1 30642.0 37890.0 34767.0 35113.0 31851.0 26655.5 22511.2 True False 30477.289692783805 26865.032480936596 27426.82989843498 28925.228082704358 30465.726495640847 32943.75731619442 31786.84244389446 31014.944998924082 27045.286260248387 26592.302361438848 1.1460944328377722 1.0102559799370072 1.0313822972397557 1.0877293620370554 1.1456596003443011 1.238845620376434 1.1953399901916033 1.166312889247922 1.01703439937816 1.0 14.698721070683868 -4.419895934073747 22.11238510304023 1.1088029568649616 8.206236070439582 0.017214630969832223 0.08091641991912067 3656.9480094195737 781399.701044936 0.021214547951913146 6393.237277345194 3.802805084667528e-05 4.419895934073747 7.0974331135746205 GS(ph)SPQNTTTPK ddPTM_PC-9_Lapatinib_30min_R1 1 GSSPQNTTTPK 11 0 Q27J81-2;Q27J81 Q27J81-2 INF2 Inverted formin-2 1 GS(0.5)S(0.5)PQNTTTPK 81.92 0.04125 0.0 8380.1 12998.0 11841.0 13403.0 14810.0 13476.0 16523.0 16206.0 11882.0 12048.0 True False 8260.598237277874 12967.903929594746 10867.47868758181 14388.7013310973 13938.904917580294 12899.662894090321 17378.48009234009 16958.989922911675 10543.724036993044 14130.480747049105 0.5845942813377352 0.9177256005463832 0.7690806054034139 1.0182740126589196 0.9864423700156969 0.9128962506660775 1.2298576675085362 1.2001707674704027 0.7461688123523263 1.0 13.786522929409921 -4.16933781150728 0.594789328265986 1.041282434216216 4.6765419959184365e-15 0.42395750800740395 0.14356400580423279 6.903550844919895 1.0872454656865713 0.06982482546759762 5.791821764411342 6.771146160611282e-05 4.16933781150728 -1.0412824342162113 GS(ph)SPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILK ddPTM_PC-9_AZD4547_30min_R2 1 GSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILK 38 1 Q27J81-2;Q27J81 Q27J81-2 INF2 Inverted formin-2 1 GS(0.461)S(0.431)PQNT(0.034)T(0.034)T(0.034)PKPS(0.006)VEGQQPAAAAACEPVDHAQSESILK 58.327 6.5298e-05 36088000.0 28538.0 25124.0 53899.0 64567.0 56089.0 54624.0 41014.0 60052.0 44085.0 48718.0 True False 37612.49037272474 33244.84167340219 53184.26404301901 49682.07570020587 48302.01051661413 51208.35264487543 44664.16654535399 50772.343257678214 46415.24309868876 47012.39764860511 0.8000547143725762 0.7071505248868877 1.1312816768152436 1.0567866814952793 1.027431335828652 1.0892520953224518 0.9500508116858236 1.0799777462357243 0.9872979345920668 1.0 15.520753639905474 -5.256209381677487 24.99939629947293 1.0417761984889249 0.753602594023053 0.8162249612972539 0.05440398313537126 154.79076270928724 739893.9555263775 0.013294359751333938 0.03303520113405165 5.543583817400019e-06 5.256209381677487 -0.2881736044658719 GS(ph)SPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILK 38 1 Q27J81-2;Q27J81 Q27J81-2 INF2 Inverted formin-2 1 GS(0.501)S(0.441)PQNT(0.015)T(0.015)T(0.015)PKPS(0.015)VEGQQPAAAAACEPVDHAQSESILK;GS(0.24)S(0.218)PQNT(0.13)T(0.13)T(0.13)PKPS(0.15)VEGQQPAAAAACEPVDHAQSESILK 71.583 5.2116e-07 35990700.0 67320.0 74127.0 84454.0 109951.0 125120.0 109996.0 100676.0 98823.0 96438.0 71504.0 True False 78715.94636939216 81485.83867172363 86467.70365357844 103790.80193595173 100603.63418143503 104227.61612310878 91139.24044887992 96229.00096162343 97848.2233072286 84467.10917464737 0.9319123992586997 0.9647049540104474 1.0236848934275065 1.2287718018305798 1.1910391531622466 1.233943213418182 1.078990879875349 1.1392481866836088 1.1584180429913131 1.0 16.366102056233807 -5.5748914090974 4.64790382668411 1.1552491057331669 0.9569082463816488 0.6005041588886945 0.06639450343499428 0.1248687403228187 5.718815212243492 0.01809776336583656 0.033126166165206944 2.661390430124546e-06 5.5748914090974 -0.19834085935151802 GS(ph)SPTPPCSPVQPSK ddPTM_PC-9_AZD4547_30min_R2 1 GSSPTPPCSPVQPSK 15 0 H0YBY0;E7EPX0;E7EVJ4;Q9NUL3-4;Q9NUL3-6;Q9NUL3-8;Q9NUL3-3;Q9NUL3-7;Q9NUL3-2;Q9NUL3 H0YBY0 STAU2 Double-stranded RNA-binding protein Staufen homolog 2 1 GS(0.5)S(0.5)PTPPCSPVQPSK 257.48 4.5481e-50 19447000.0 45155.0 46360.0 68671.0 91160.0 88645.0 68334.0 63027.0 75114.0 63913.0 68390.0 True False 59513.35071765317 61344.96338078829 67760.3776711657 70144.4704079602 76338.17187407968 64061.06417755778 68636.28090052247 63506.85724800577 67291.31069902453 65995.68691629599 0.9017763659788172 0.9295298866817413 1.0267394861289634 1.062864464111514 1.1567145587999004 0.9706856185739541 1.0400116145101364 0.9622879951011516 1.0196319463175194 1.0 16.01008412117512 -5.2180861655928945 3.6452644678466695 1.033082860063366 0.9083023938677268 0.44383319374560004 0.05146043741185736 0.21870209616713257 6.060328984105823 0.014326754404614036 0.0419515566251556 6.052207848527754e-06 5.2180861655928945 -0.1247804661956391 GS(ph)SQPNLSTSHSEQEYGK ddPTM_PC-9_AZD4547_30min_R2 1 GSSQPNLSTSHSEQEYGK 18 0 F6PQP6;E9PBC1;I3L2B2;O95208-2;O95208;O95208-3 F6PQP6 EPN2 Epsin-2 1 GS(0.325)S(0.263)QPNLS(0.133)T(0.233)S(0.046)HSEQEYGK 96.12799999999999 0.00048374 52753000.0 38186.0 30839.0 81308.0 92374.0 76943.0 73638.0 52485.0 84722.0 59508.0 81626.0 True False 50328.35368185811 40807.10366048601 80229.80279429661 71078.6014640732 66260.7925828566 69033.40421908564 57156.06332308248 71630.16161788136 62653.47139201019 78768.29858502079 0.6389417390745692 0.5180650641633412 1.0185544722373088 0.9023757366975815 0.8412114235441576 0.8764110112721615 0.7256226724434002 0.9093780480806668 0.7954148117644486 1.0 16.26532749303327 -5.251208851395534 24.999704264457126 0.8736394089497996 0.5785033727343168 0.6625392851021895 0.08686962478908397 411.0402474811518 1004428.7335473531 0.02177281178627048 0.056245877355635396 5.6077823398559195e-06 5.251208851395534 -0.2951360362154828 GS(ph)SQPNLSTSHSEQEYGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSSQPNLSTSHSEQEYGK 18 0 F6PQP6;E9PBC1;I3L2B2;O95208-2;O95208;O95208-3 F6PQP6 EPN2 Epsin-2 1 GS(0.525)S(0.427)QPNLS(0.041)T(0.004)S(0.003)HSEQEYGK 73.404 0.0040126 9187800.0 15359.0 22772.0 39537.0 43432.0 60320.0 49105.0 38871.0 34884.0 39245.0 27501.0 True False 17958.975345922372 25032.653665094935 40479.71202490748 40998.645848443826 48500.72901074311 46529.847355588 35188.857478330596 33968.331962653225 39818.88388075432 32486.7136022038 0.5528098522315317 0.7705505078666005 1.246038996759631 1.262012721584205 1.4929404557392032 1.432273141732365 1.0831768922278273 1.0456069019043193 1.2256975072434884 1.0 14.98756218570957 -5.13594672802306 2.9225093304520016 1.2410433543452257 0.5749591862241481 0.698293586899142 0.1502397752244724 0.15833756485032285 2.4929931370921605 0.043627305382332005 0.16337731193484378 7.312287728875783e-06 5.13594672802306 -0.6660841681210776 GS(ph)SQPNLSTSHSEQEYGK ddPTM_PC-9_Lapatinib_30min_R1 3 GSSQPNLSTSHSEQEYGK 18 0 F6PQP6;E9PBC1;I3L2B2;O95208-2;O95208;O95208-3 F6PQP6 EPN2 Epsin-2 1 GS(0.407)S(0.407)QPNLS(0.054)T(0.066)S(0.066)HSEQEYGK;GS(0.512)S(0.45)QPNLS(0.007)T(0.006)S(0.023)HS(0.003)EQEYGK;GS(0.579)S(0.421)QPNLSTSHSEQEYGK 142.89 0.00010918 51744200.0 147069.0 133362.0 224112.0 157585.0 191673.0 205845.0 122822.0 176218.0 211315.0 122991.0 True False 144971.76909084854 133053.20848273707 205686.37645733773 169174.3265881499 180399.17098361702 197041.48919813166 129181.12218733861 184405.73159543652 187514.47945440057 144249.8304747936 1.0050047796498527 0.9223803455768148 1.4259037655734343 1.172787004541483 1.2506023084383466 1.3659738007980742 0.8955374281005613 1.2783774579732337 1.2999285949744468 1.0 17.138210097825294 -5.233068800692356 24.95041963535665 1.2153789135612538 0.9636924800452846 0.295454282761881 0.15273239528631732 845.756440840122 743795.383125158 0.03766869713053626 0.09961735892071147 5.846974493595691e-06 5.233068800692356 -0.2516864335159692 GS(ph)SSQGPSQTSTPTDVTAIHL ddPTM_PC-9_AZD4547_30min_R2 1 GSSSQGPSQTSTPTDVTAIHL 21 0 Q5T8J1;P30281-4;P30281-2;P30281-3;P30281 Q5T8J1 CCND3 G1/S-specific cyclin-D3 1 GS(0.499)S(0.499)S(0.003)QGPSQTSTPTDVTAIHL 233.38 3.4742999999999994e-109 0.0 1405.3 3690.7 2037.7 5362.1 3931.3 4621.8 3820.9 4227.7 1625.5 3634.3 True False 1852.156167944148 4883.646599427858 2010.6787665904717 4125.950688619169 3385.5068541775563 4332.798115372095 4160.952697935904 3574.406107881276 1711.4206114759781 3507.0642631948263 0.5281215366886067 1.3925169979574334 0.5733224759214438 1.176468515823704 0.965339269572855 1.2354487372367253 1.1864489458044336 1.0192017709493306 0.4879923728334899 1.0 11.776048151335806 -12.320221328026275 2.157127076015771 2.1680715634829575 0.9777449988018536 0.0 0.30478589938810463 24999547.28323948 5403908.883198671 144297991.32920617 0.07369258749011663 4.783862318335233e-13 12.320221328026275 -1.1903265646811039 GS(ph)SSQGPSQTSTPTDVTAIHL ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSSSQGPSQTSTPTDVTAIHL 21 0 Q5T8J1;P30281-4;P30281-2;P30281-3;P30281 Q5T8J1 CCND3 G1/S-specific cyclin-D3 1 GS(0.515)S(0.388)S(0.097)QGPSQTSTPTDVTAIHL;GS(0.493)S(0.423)S(0.071)QGPS(0.001)QT(0.002)S(0.003)T(0.006)PTDVTAIHL 161.51 1.9250999999999996e-23 0.0 1926.17 4332.0 5955.2 5137.4 6944.900000000001 6078.3 4981.2 5971.7 7198.1 4404.3 True False 2252.2325374083794 4762.052330809378 6097.194553221768 4849.568133675522 5584.096699381791 5759.543247764388 4509.344675235015 5814.949202539159 7303.35859503269 5202.764725580386 0.43289148293307367 0.9152926534224849 1.1719143330167798 0.9321136721465983 1.073294103023055 1.1070158947312174 0.866720851908594 1.1176652240200007 1.4037456968069943 1.0 12.34506275328498 -4.789263183855694 2.910303529724825 1.0752870400235062 0.32776334410229085 0.6676239330182172 0.13816679138104992 0.2376008102617706 2.8855531469390567 0.03565952297443173 0.4211952008005218 1.62456396638852e-05 4.789263183855694 -0.7475236959212153 GS(ph)SSSSPEHSASSDSTK ddPTM_PC-9_Lapatinib_30min_R1 1 GSSSSSPEHSASSDSTK 17 0 A0A075B784;Q9P275 A0A075B784 USP36 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 36 1 GS(0.2)S(0.2)S(0.2)S(0.2)S(0.2)PEHSASSDSTK 66.82600000000001 0.011112 6719100.0 16455.0 15186.0 35923.0 21850.0 25532.0 26874.0 15265.0 17520.0 30067.0 14389.0 True False 16220.34868252257 15150.837750025063 32969.54960679005 23456.921889463254 24030.25795784334 25724.661666353757 16055.347007781365 18334.04315990451 26680.53784045363 16876.11947786269 0.9611420862360966 0.8977678648162707 1.9536214856761343 1.3899476073414245 1.4239208242964336 1.5243232723078417 0.9513648578301442 1.0863897464078907 1.580964028813136 1.0 14.042695586103555 -7.251872133904326 24.776324209754478 1.1618787966169566 1.368973951266152 0.08912446574587674 0.3177450480748396 1676.1968804282267 4340858.965786883 0.12840732646298514 0.09815689890554552 5.599224310279433e-08 7.251872133904326 0.20709515464919548 GS(ph)T(ph)S(ph)GFLNIMMELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSTSGFLNIMMELK 14 0 O14646;O14646-2 O14646 CHD1 Chromodomain-helicase-DNA-binding protein 1 3 GS(1)T(1)S(1)GFLNIMMELK 61.958 0.030904 0.0 914.69 0.0 1109.0 923.36 1505.9 1031.1 0.0 1004.6 0.0 799.38 True False 1069.528951049009 0.0 1135.4427659059204 871.627132773511 1210.8297051936015 977.0273008521891 0.0 978.2303144616848 0.0 944.3012661114014 1.1326141237248264 0.0 1.2024158037843502 0.9230392503473389 1.2822493717283199 1.0346563495308572 0.0 1.035930321781736 0.0 1.0 9.883103394473498 -7.187272469934444 24.99970239839964 0.5119472736213545 0.9151198122804628 0.16402376453847722 0.46404294796502243 259.8326831975035 87581.83642392582 0.17216433845793008 0.13335791810740022 6.497219365139517e-08 7.187272469934444 0.4031725386591083 GS(ph)TESCNTTTEDEDLKVR ddPTM_PC-9_Lapatinib_30min_R1 1 GSTESCNTTTEDEDLKVR 18 1 Q5SWX3;Q13555-5;Q13555-11;Q8WU40;Q13555-10;Q13555-4 Q5SWX3 CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 1 GS(0.488)T(0.488)ES(0.024)CNTTTEDEDLKVR 112.57 8.280700000000001e-05 13932000.0 5174.3 7127.4 12109.0 13076.0 9152.2 10534.0 8472.0 11075.0 10815.0 15781.0 True False 5100.513533149596 7110.8969432061485 11113.444762091716 14037.65266025729 8613.885589917507 10083.485375953362 8910.638706185635 11589.58493127526 9596.90081300117 18508.724823139277 0.27557347045178526 0.384191618339705 0.6004435674681319 0.7584343489027222 0.465395950948959 0.5447963310442202 0.48142909851065013 0.6261687416080749 0.5185068612076017 1.0 14.175917882283304 -14.522878745280336 0.1880524371234588 2.990555655921397 0.4378822848297997 0.6027351312979103 0.12084008053582215 104.60346412245188 1.0173266290553127 78.1374268205783 0.36410220420037104 3.0000000000000132e-15 14.522878745280336 -2.552673371091597 GS(ph)VGRVSQCNLCPTR ddPTM_PC-9_AZD4547_30min_R2 1 GSVGRVSQCNLCPTR 15 1 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;Q9NUQ6-2 B8ZZZ7 SPATS2L SPATS2-like protein 1 GS(0.612)VGRVS(0.387)QCNLCPTR 67.252 0.014254 9665100.0 9181.1 12272.0 11657.0 16425.0 18820.0 11159.0 14331.0 16316.0 15157.0 11722.0 True False 12100.498821256677 16238.684007960184 11502.42056345151 12638.470013720354 16207.167856846761 10461.22596595205 15606.43123717434 13794.737104380845 15958.168076371225 11311.616347899122 1.0697409149227441 1.4355759166970117 1.0168679885954428 1.1173000944350155 1.4327897409512902 0.9248214971412981 1.3796818029523148 1.2195195346191976 1.4107769911534433 1.0 13.465517474260462 GS(ph)VHSLDAGLLLPSGDPFSK ddPTM_PC-9_AZD4547_30min_R2 2 GSVHSLDAGLLLPSGDPFSK 20 0 I3L456;Q15276-2;Q15276 I3L456 RABEP1 Rab GTPase-binding effector protein 1 1 GS(0.619)VHS(0.381)LDAGLLLPSGDPFSK;GS(0.85)VHS(0.15)LDAGLLLPSGDPFSK 94.359 0.00032972 5185900.0 24844.9 17723.4 83484.0 143501.0 105364.0 97337.0 64726.0 124405.0 64309.0 89427.0 True False 32745.061393976754 23452.142450022948 82376.94761252345 110419.06151834916 90736.02731502666 91250.50200267714 70486.48860912335 105181.06579250422 67708.24245057435 86296.18794946047 0.37944968569357856 0.2717633653036649 0.9545838532377313 1.2795357957528357 1.0514488469428847 1.0574105782762755 0.8167972454403652 1.2188379149969373 0.7846029362296724 1.0 16.39700921070481 -5.298572443781555 5.390099669768729 1.036204200233872 0.3224413221934548 0.7820629851201247 0.14680147919367728 0.07136697865387014 5.68772232268658 0.037331533251086894 0.08346055498384142 5.028373815707486e-06 5.298572443781555 -0.7137628780404173 down GS(ph)VHSLDAGLLLPSGDPFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSVHSLDAGLLLPSGDPFSK 20 0 I3L456;Q15276-2;Q15276 I3L456 RABEP1 Rab GTPase-binding effector protein 1 1 GS(0.807)VHS(0.193)LDAGLLLPSGDPFSK;GS(0.541)VHS(0.459)LDAGLLLPSGDPFSK 82.885 0.0005621000000000001 3299100.0 18585.2 24411.4 54204.0 57330.0 72683.0 71000.0 50108.0 46614.0 53675.0 40170.0 True False 21731.307285567837 26834.802462677788 55496.42892981471 54117.9859663678 58441.28790928123 67276.63501164339 45361.4074894957 45390.431891615546 54459.89533187641 47452.50301445496 0.45795913608494065 0.5655086825346891 1.1695153132998994 1.140466414382449 1.2315743995944506 1.4177678886854421 0.9559328719852297 0.9565445236426987 1.1476717111273742 1.0 15.534196567771627 -5.222882451514683 4.896461950001587 1.1352822637066138 0.4924132945710183 0.7749943732072432 0.1328737917793472 0.09255592266178472 5.549081592135795 0.03704445920695406 0.10019392373954558 5.9857358628979515e-06 5.222882451514683 -0.6428689691355955 down GS(ph)VSDEEMMELR ddPTM_PC-9_AZD4547_30min_R2 12 GSVSDEEMMELR 12 0 P13796;Q5TBN3;Q5TBN5 P13796 LCP1 Plastin-2 1 GS(0.776)VS(0.224)DEEMMELR;GS(0.999)VS(0.001)DEEMMELR;GS(0.895)VS(0.105)DEEMMELR;GS(0.879)VS(0.121)DEEMMELR;GS(0.817)VS(0.183)DEEMMELR;GS(0.68)VS(0.32)DEEMMELR;GS(0.761)VS(0.239)DEEMMELR;GS(0.992)VS(0.008)DEEMMELR;GS(0.972)VS(0.028)DEEMMELR;GS(0.99)VS(0.01)DEEMMELR;GS(0.775)VS(0.225)DEEMMELR;GS(0.997)VS(0.003)DEEMMELR 195.71 1.2963e-12 682907500.0 648941.9 784711.9 1004386.4 1050120.7 912321.8 1045622.1 875428.9 1161951.0 916481.6 857432.4 True False 855291.9253699522 1038354.6757974302 991067.5800815852 808031.5968180844 785661.6658905722 980239.1847919452 953340.3761695054 982398.1719277052 964924.94634173 827413.952658112 1.0336928965510923 1.2549397704276797 1.1977893011082628 0.9765747776215753 0.9495388171381346 1.1847022661907909 1.1521927725618453 1.1873115854182759 1.1661937090157308 1.0 19.65824976034071 GS(ph)VSDEEMMELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 GSVSDEEMMELR 12 0 P13796;Q5TBN3;Q5TBN5 P13796 LCP1 Plastin-2 1 GS(0.948)VS(0.052)DEEMMELR;GS(0.966)VS(0.034)DEEMMELR;GS(0.983)VS(0.017)DEEMMELR;GS(0.873)VS(0.127)DEEMMELR;GS(0.874)VS(0.126)DEEMMELR;GS(0.969)VS(0.031)DEEMMELR 123.28 0.00031904 307558100.0 363690.0 426619.0 500508.0 524257.0 689331.0 638597.0 870377.0 680114.0 698995.0 550740.0 True False 425255.53379507136 468970.9148932521 512442.0089071608 494884.5799541267 554261.5389539873 605107.849134231 787928.5895762123 662261.7281403489 709216.4795063789 650584.8023445585 0.6536511954514582 0.7208451737624186 0.7876636636153154 0.760676514684444 0.8519435697799207 0.9300983468312831 1.211108201016529 1.0179483531642752 1.0901214983051022 1.0 19.311377595865615 -6.7306619981853 1.6385847948773957 1.0815172623585432 0.7304970375435177 0.8443753966878396 0.06657684048987303 0.13547844608396337 0.754025784756491 0.02823393170386575 0.026326636111983468 1.859250906113254e-07 6.7306619981853 -0.3510202248150255 GS(ph)VSDEEMMELR ddPTM_PC-9_Lapatinib_30min_R1 14 GSVSDEEMMELR 12 0 P13796;Q5TBN3;Q5TBN5 P13796 LCP1 Plastin-2 1 GS(0.826)VS(0.174)DEEMMELR;GS(0.675)VS(0.325)DEEMMELR;GS(0.843)VS(0.157)DEEMMELR;GS(0.971)VS(0.029)DEEMMELR;GS(0.756)VS(0.244)DEEMMELR;GS(0.967)VS(0.033)DEEMMELR;GS(0.687)VS(0.313)DEEMMELR;GS(0.61)VS(0.39)DEEMMELR;GS(0.986)VS(0.014)DEEMMELR;GS(1)VSDEEMMELR;GS(0.983)VS(0.017)DEEMMELR;GS(0.547)VS(0.453)DEEMMELR;GS(0.912)VS(0.088)DEEMMELR;GS(0.99)VS(0.01)DEEMMELR 238.07 8.178099999999999e-22 412324200.0 226142.88 372954.9 448912.1 382348.2 726523.0 913152.4 1066931.4 1046330.5 976497.4 863876.6000000001 True False 222918.04106167512 372091.34584333113 412004.2799888182 410467.3621042046 683790.3455391752 874099.0005142118 1122171.887356566 1094946.834847287 866513.9798385138 1013196.5192667863 0.22001461396945268 0.3672449902538159 0.406638072826159 0.4051211727427222 0.6748842228889708 0.8627141762653959 1.107556003221015 1.0806855472022945 0.8552279477485558 1.0 19.950482595264198 -6.529514390235216 1.425691954722887 1.0204232193808904 0.32678255284101926 0.9355142362098006 0.0789388473806489 0.09455039612612579 0.39531848401015857 0.03377725121169863 0.03728056481457505 2.9545109899007164e-07 6.529514390235216 -0.6936406665398711 down GS(ph)YGDLGGPIITTQVTIPK ddPTM_PC-9_AZD4547_30min_R2 4 GSYGDLGGPIITTQVTIPK 19 0 P61978;P61978-2;P61978-3;Q5T6W2;S4R359 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 GS(1)YGDLGGPIITTQVTIPK;GS(1)YGDLGGPIITTQVTIPK;GS(1)YGDLGGPIITTQVTIPK;GS(1)YGDLGGPIITTQVTIPK 263.52 2.916e-78 27281500.0 163772.8 215285.0 234443.0 223158.0 253229.0 340209.0 325998.0 400368.0 342685.0 281365.0 True False 215849.14371414133 284871.6661223685 231334.13263766532 171712.37085673088 218072.52440071446 318935.6774487484 355011.19045819255 338500.32514138025 360798.62949470716 271514.4969908402 0.7949820216097825 1.0491950495445512 0.8520139263336264 0.6324243189951061 0.8031708318251285 1.174654322268133 1.3075220453888663 1.2467117921618744 1.3288374414382709 1.0 18.050669704431208 -6.814906281582582 4.934011702280709 1.2396296825520936 0.828741869152775 0.6968085388071728 0.1268465403875644 0.11490808711203142 5.84477114374562 0.0467436550460051 0.04190358693248239 1.5314178977875646e-07 6.814906281582582 -0.41088781339931857 GS(ph)YGDLGGPIITTQVTIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GSYGDLGGPIITTQVTIPK 19 0 P61978;P61978-2;P61978-3;Q5T6W2;S4R359 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 GS(1)YGDLGGPIITTQVTIPK;GS(1)YGDLGGPIITTQVTIPK;GS(1)YGDLGGPIITTQVTIPK;GS(1)YGDLGGPIITTQVTIPK 230.67 7.372099999999999e-102 24422000.0 104501.0 184642.0 186515.0 186953.0 206599.0 140080.0 200238.0 134497.0 144358.0 138402.0 True False 122190.95531116812 202972.03750353312 190962.22496207693 176478.62951980345 166117.40903333083 132733.9582032536 181270.0070424216 130966.59626135095 146468.9626514951 163493.18701037104 0.7473764353460004 1.2414709212969086 1.168013349387846 1.0794249763362231 1.0160509564401197 0.8118623205677294 1.1087312588195062 0.8010523169570558 0.8958719646354681 1.0 17.318870992293846 -6.531394798895768 23.249404911838628 0.9216805183101406 1.0758636046762513 0.16069833723645455 0.1456822103987155 134.75337506288997 367878.97177829384 0.04687829488559339 0.04697461178850788 2.9417461998503353e-07 6.531394798895768 0.15418308636611067 GS(ph)YGDLGGPIITTQVTIPK ddPTM_PC-9_Lapatinib_30min_R1 4 GSYGDLGGPIITTQVTIPK 19 0 P61978;P61978-2;P61978-3;Q5T6W2;S4R359 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 GS(1)YGDLGGPIITTQVTIPK;GS(1)YGDLGGPIITTQVTIPK;GS(1)YGDLGGPIITTQVTIPK;GS(1)YGDLGGPIITTQVTIPK 238.8 7.487499999999998e-74 36163100.0 153329.0 283380.0 304180.0 247532.0 307283.0 306494.0 315007.0 315474.0 277539.0 262657.0 True False 151142.50034290494 282723.851020816 279171.49456875585 265736.3290225453 289209.21808162204 293385.96609241 331316.52111891174 330132.0737344589 246279.63520476484 308056.9124815464 0.49063174439222773 0.9177649959007237 0.9062335018548857 0.8626208932690766 0.9388174923649752 0.9523758572045831 1.0755042581255458 1.0716593601977196 0.7994614800910134 1.0 18.232837383051454 -4.514622968097341 2.023713513423282 0.9564351074439793 1.569762662509293e-08 0.7348227813981343 0.0820600849891614 1.0678878401258836 2.4281078314506503 0.022813063749120566 2.451200371276829 3.057574388539409e-05 4.514622968097341 -0.9564350917463527 down GS(ph)YGSDAEEEEYRQQLSEHSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSYGSDAEEEEYRQQLSEHSK 21 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-6;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 GS(0.49)Y(0.084)GS(0.425)DAEEEEY(0.001)RQQLS(0.001)EHSK 42.663000000000004 0.041135000000000005 11212000.0 21969.0 27383.0 38961.0 55188.0 46841.0 53055.0 37598.0 37977.0 37680.0 32433.0 True False 25687.917792471442 30101.40327205755 39889.9780004153 52095.99528191007 37662.842300932 50272.702402010415 34036.44525405245 36980.143989957585 38230.998716443464 38312.84616051325 0.6704779301660558 0.785673900235615 1.0411645700581627 1.359752680958542 0.9830343102974385 1.3121630847103047 0.888382061501131 0.9652152657891233 0.9978637075479363 1.0 15.22554058331012 -5.198322908548837 3.404679075404234 1.078471692428743 0.6977334691724341 0.4805127673362535 0.14361699750955514 0.20780831327181964 4.733687992066008 0.03868287809837494 0.12007041172795331 6.33398588820464e-06 5.198322908548837 -0.3807382232563089 GSAAPS(ph)PTVRPPDEPPMSSGADTTQPGMEVDAPHLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSAAPSPTVRPPDEPPMSSGADTTQPGMEVDAPHLR 36 1 A0A6E1W9L1;Q9H5J0 A0A6E1W9L1 ZBTB3 Zinc finger and BTB domain-containing protein 3 1 GS(0.111)AAPS(0.646)PT(0.213)VRPPDEPPMS(0.008)S(0.009)GADT(0.009)T(0.003)QPGMEVDAPHLR 45.27 0.0025368 3812700.0 1175.9 988.83 3393.4 2920.4 4168.2 1328.1 1092.2 1286.9 2734.9 3411.2 True False 1374.9566449163442 1086.994507450194 3474.311525541166 2756.7794560645475 3351.4711316740627 1258.4520980135705 988.7389091567661 1253.1202385832585 2774.8927385775273 4029.623556955656 0.3412121816051501 0.26975088171050116 0.8621925786452312 0.6841282857069828 0.8317082437859452 0.3123001640789294 0.24536756229997558 0.3109769984395216 0.6886233166340564 1.0 11.97642935471061 -8.549213854971928 7.646105981165845 0.99999276571407 0.49285796383593594 0.3454940702591176 0.22080083476553108 0.45519902322889777 127.86199015533889 0.23527898936802402 0.06083205069373926 2.8234892920070566e-09 8.549213854971928 -0.5071348018781341 GSAITGPVAK ddPTM_PC-9_Lapatinib_30min_R1 2 GSAITGPVAK 10 0 P62829;J3KTJ3 P62829 RPL23 60S ribosomal protein L23 0 ; 119.75 0.0035192 29375000.0 106876.0 104791.0 94801.0 111063.0 113932.0 125667.0 113589.0 105134.0 105354.0 100200.0 False True 105351.928641342 104548.36287783977 87006.82772244258 119230.94351530673 107230.74375893027 120292.51535408488 119470.08262475433 110018.90945053648 93487.9230931968 117519.43649189248 0.8964638683287943 0.8896261418429489 0.7403611719023608 1.014563608152872 0.912451139657464 1.0235967678621716 1.0165984980109772 0.9361762848320545 0.7955103077748881 1.0 16.842539857707926 -5.778211797829443 24.999941401260088 0.9577296830946875 0.8468979146826936 0.3253210692121081 0.0756857414494427 289.1274246205125 430954.8087562153 0.021793347817413683 0.03242078685490439 1.6664343234529879e-06 5.778211797829443 -0.11083176841199394 GSALGPNPEPHLT(ph)FPR ddPTM_PC-9_AZD4547_30min_R2 2 GSALGPNPEPHLTFPR 16 0 Q5T0Z8 Q5T0Z8 C6orf132 Uncharacterized protein C6orf132 1 GSALGPNPEPHLT(1)FPR;GSALGPNPEPHLT(1)FPR 98.56200000000001 0.0042646 6461400.0 25403.0 25095.0 36193.0 50644.0 40263.0 49558.0 41686.0 50454.0 44870.0 45800.0 True False 33480.62558477562 33206.4679905281 35713.05717191391 38968.808242000225 34673.17743996922 46459.1304257238 45395.97324351752 42657.49361757974 47241.736596079456 44196.55594043505 0.7575392442320258 0.7513361003803418 0.8080506820496468 0.881715948512359 0.7845221579414298 1.0511934569819894 1.0271382526887154 0.9651768720411259 1.068900858694702 1.0 15.431646330133434 -6.758977536730639 24.999999966345396 1.0205964827867082 0.7994774797043402 0.8765896304787197 0.04236105157760979 23.028020268618327 233849.86465437541 0.01516762394429857 0.014496848764481403 1.7418969682247408e-07 6.758977536730639 -0.22111900308236798 GSALGPNPEPHLT(ph)FPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSALGPNPEPHLTFPR 16 0 Q5T0Z8 Q5T0Z8 C6orf132 Uncharacterized protein C6orf132 1 GSALGPNPEPHLT(1)FPR 102.43 0.00315 3377600.0 25819.0 27893.0 33587.0 37559.0 34150.0 27653.0 27761.0 26862.0 27653.0 25040.0 True False 30189.646751505297 30662.032701584958 34387.841459406816 35454.69099792093 27458.552647826204 26202.82799967567 25131.277107765043 26156.900962641615 28057.372810663757 29579.553783469048 1.0206254959930197 1.0365955120905463 1.1625544357814128 1.1986215633088855 0.9282950259774305 0.8858425719159931 0.8496165050944755 0.8842899103251439 0.948539420711073 1.0 14.852312668658778 -6.372181235001992 6.298753448624688 0.9032696982806567 1.1032625100148723 0.684604327363725 0.062472150168792706 0.1412929516307641 7.003110934659107 0.020747225583444814 0.023537681264749283 4.244424033427222e-07 6.372181235001992 0.19999281173421557 GSALGPNPEPHLT(ph)FPR ddPTM_PC-9_Lapatinib_30min_R1 2 GSALGPNPEPHLTFPR 16 0 Q5T0Z8 Q5T0Z8 C6orf132 Uncharacterized protein C6orf132 1 GSALGPNPEPHLT(1)FPR;GSALGPNPEPHLT(1)FPR 84.03 0.010634999999999999 6879500.0 76496.0 45814.0 63737.0 56063.0 53948.0 49476.0 42199.0 30919.1 50764.0 38376.0 True False 75405.15301235163 45707.92049780378 58496.78989193494 60186.06004068556 50774.884705848825 47360.02681418915 44383.85773870722 32355.714261723948 45046.42375138152 45009.24046719428 1.675326049265637 1.015523035344681 1.2996617868851015 1.3371934166397044 1.1280991231757604 1.0522289717087823 0.986105459190255 0.7188682574038755 1.000826125564468 1.0 15.457933598939482 -6.7395185393386425 1.2318911180877845 0.8958550609063579 1.3172384465927798 0.5354912994841681 0.16844460572678535 0.35392825779352627 1.1324899871936625 0.08054514995907541 0.07412654509896766 1.821719305140871e-07 6.7395185393386425 0.42138338568642186 GSAPPGPVPEGSIR ddPTM_PC-9_Lapatinib_30min_R1 1 GSAPPGPVPEGSIR 14 0 P78417-2;P78417 P78417-2 GSTO1 Glutathione S-transferase omega-1 0 96.06700000000001 0.019737 0.0 5900.9 6845.2 7381.2 7765.4 6820.2 8638.9 5145.6 4277.7 7406.3 6372.6 False True 5816.752083907472 6829.350359967836 6774.346228255962 8336.493420615016 6419.049245029105 8269.434385259487 5412.013990385835 4476.45755851162 6572.124502203471 7474.095419044254 0.7782549937864301 0.9137360412293392 0.9063767383802317 1.1153849333222776 0.8588396167211279 1.1064127391508383 0.7241028762619 0.5989296774437012 0.8793203904592213 1.0 12.867683266858563 -7.288295232200941 24.967332960249454 0.7671656911424125 0.9468796817787183 0.19728758267361657 0.13773794808402892 981.890707858245 912839.3408849726 0.0560753353422473 0.03781706815973167 5.14878512581265e-08 7.288295232200941 0.17971399063630578 GSASTS(ph)LPNETLSELETPGK ddPTM_PC-9_AZD4547_30min_R2 2 GSASTSLPNETLSELETPGK 20 0 Q99990;H0Y5G3;Q5H916 Q99990 VGLL1 Transcription cofactor vestigial-like protein 1 1 GS(0.003)AS(0.016)T(0.113)S(0.85)LPNET(0.016)LS(0.002)ELETPGK;GSAS(0.011)T(0.214)S(0.775)LPNETLSELETPGK 180.76 8.3618e-10 7948300.0 63886.0 54744.0 70296.0 106429.0 86450.0 87327.0 75636.0 90425.0 89423.0 88570.0 True False 84200.41908864999 72438.92742273246 69363.82910940953 81893.43836165869 74447.9097356218 81866.4288850878 82367.4574736527 76451.89400978423 94149.71721932723 85469.19125860966 0.9851552103012106 0.8475443180870791 0.8115652913987558 0.9581632533981562 0.8710496570671874 0.9578472392160498 0.9637093350331134 0.8944965183823816 1.10156321632262 1.0 16.383116850677972 -7.67643569632069 0.809080763123997 1.0291685708249203 0.8899982917947538 0.3613914615635371 0.06433493651542269 0.6875474949423629 0.8376745070471497 0.056510823559123624 0.026374292762744472 2.1065137762181003e-08 7.67643569632069 -0.13917027903016654 GSASTS(ph)LPNETLSELETPGK ddPTM_PC-9_Lapatinib_30min_R1 1 GSASTSLPNETLSELETPGK 20 0 Q99990;H0Y5G3;Q5H916 Q99990 VGLL1 Transcription cofactor vestigial-like protein 1 1 GSAS(0.009)T(0.044)S(0.946)LPNETLSELETPGK 176.11 5.5517e-37 0.0 8427.1 9951.1 11089.0 9294.1 12825.0 13619.0 11662.0 13034.0 12460.0 14753.0 True False 8306.928008659128 9928.058839343767 10177.305224777856 9977.61911820872 12070.658714920135 13036.547117439597 12265.80129739576 13639.607222956365 11056.623590383217 17303.036392863163 0.48008498740055916 0.5737755278280932 0.5881803051038835 0.5766397811151865 0.6976034980715187 0.7534254001116631 0.7088814366971412 0.7882782485842877 0.6389990368941054 1.0 14.07873760842552 -8.37549711771469 0.07398159366743823 1.5439134225627196 3.9559629019181e-15 0.8221353409518126 0.058544591210067935 9.314180716342204 0.5387263698646156 5.782287592712095 5.011942774744156 4.212140822193171e-09 8.37549711771469 -1.5439134225627156 GSASYS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 1 GSASYSPPR 9 0 A0A087WTY1;P0DPB5 A0A087WTY1 POLR1D 1 GS(0.002)AS(0.031)Y(0.001)S(0.966)PPR 78.098 0.022097 61314000.0 79984.0 71719.0 78607.0 68378.0 91177.0 76228.0 63249.0 70509.0 81521.0 70942.0 True False 78843.41349273079 71552.93906190223 72144.23589179489 73406.74622232128 85814.14812087902 72967.90613614702 66523.7237402662 73785.10554575939 72339.24652581303 83204.23017572671 0.9475890027011138 0.8599675630768167 0.867074134805728 0.8822477663369612 1.0313676112337098 0.8769735142316605 0.7995233367314208 0.8867951231557073 0.8694178934536511 1.0 16.34436925765624 -4.7354735073514895 22.885766060883235 0.8926275812998329 0.9475897554787748 0.04804472193935261 0.0648777224490888 2793.0575757522984 2461365.2917303783 0.01644368270730574 1.0145738621882663 1.8387661180768134e-05 4.7354735073514895 0.05496217417894189 GSAT(ph)PSGQESR ddPTM_PC-9_AZD4547_30min_R2 1 GSATPSGQESR 11 0 Q14781 Q14781 CBX2 Chromobox protein homolog 2 1 GS(0.001)AT(0.913)PS(0.086)GQES(0.001)R 111.72 0.0043457 5194000.0 14267.0 11649.0 17995.0 34173.0 28072.0 24360.0 17155.0 22057.0 21271.0 25738.0 True False 18803.609227964942 15414.311441389189 17756.374542275866 26294.942817586936 24174.68735799162 22836.76534909866 18681.76176636144 18648.59746943663 22395.341634392833 24836.9204540375 0.7570829589265049 0.6206208805119168 0.7149185252308276 1.0587038303016516 0.9733367469098518 0.9194684740147124 0.7521770583810251 0.7508417762156623 0.9016955896701049 1.0 14.600198683497837 -5.600717363095513 9.79722419503631 0.8942008637360614 0.6836120483858366 0.4914227950196881 0.09762625142424829 0.3111414245178041 36.45675216958146 0.02904872040417902 0.05036227315387388 2.507740748541543e-06 5.600717363095513 -0.2105888153502249 GSAT(ph)PSGQESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSATPSGQESR 11 0 Q14781 Q14781 CBX2 Chromobox protein homolog 2 1 GS(0.011)AT(0.962)PS(0.027)GQESR;GS(0.002)AT(0.911)PS(0.086)GQES(0.001)R 140.01 0.00028577 7553800.0 26947.0 30752.0 34857.0 32593.0 39273.0 36150.0 35560.0 31160.0 31025.0 25901.0 True False 31508.594872489775 33804.85532711219 35688.12307590864 30766.919877931723 31577.737573589406 34254.23036156207 32191.499367894718 30342.083016749035 31478.68193146653 30596.6462677968 1.0298055086401023 1.1048549253155258 1.1664063689709239 1.005565106993904 1.0320653217089748 1.1195419936470261 1.0521250952192271 0.9916800276468308 1.0288278543978226 1.0 14.901085905735997 -7.5857268719804605 5.160732025725215 1.00866675682081 1.0772739566108127 0.317043684084255 0.04553386786322832 0.26111772080262224 13.745978947374063 0.02301539904240318 0.013066195158171909 2.5958113559600942e-08 7.5857268719804605 0.06860719979000263 GSAT(ph)PSGQESR ddPTM_PC-9_Lapatinib_30min_R1 1 GSATPSGQESR 11 0 Q14781 Q14781 CBX2 Chromobox protein homolog 2 1 GS(0.012)AT(0.98)PS(0.008)GQESR 126.34 0.0010157999999999999 3948400.0 15612.0 16120.0 20617.0 14470.0 17309.0 15109.0 17825.0 16004.0 19330.0 14724.0 True False 15389.370017109844 16082.675130409843 18921.949843921473 15534.172070504957 16290.918650803325 14462.823290799246 18747.891281605152 16747.60426547442 17152.85184607606 17269.02378150324 0.8911546021259937 0.9313019273061579 1.0957162421762758 0.8995396767675731 0.9433607166753942 0.8375009192060004 1.0856370064002066 0.9698060803768589 0.9932728139762241 1.0 14.075898909122055 -7.274852306670887 24.998873519307562 1.0096628038930622 0.9393473047370017 0.24068250356296617 0.06821627248112601 1422.5404741797672 2651306.1864518817 0.02917260551992875 0.019794328364300295 5.3106501623476676e-08 7.274852306670887 -0.0703154991560605 GSATAES(ph)PVACSNSCSSFILMDDLSPK ddPTM_PC-9_AZD4547_30min_R2 1 GSATAESPVACSNSCSSFILMDDLSPK 27 0 G1UD79;Q7Z309-3;Q7Z309-2;Q7Z309 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 GS(0.023)AT(0.077)AES(0.899)PVACS(0.001)NSCSSFILMDDLSPK 94.869 2.1973000000000003e-09 4772900.0 25414.0 21601.0 28180.0 42956.0 38850.0 32766.0 26786.0 29137.0 28028.0 30805.0 True False 33495.123355961376 28583.100819422096 27806.314787515104 33053.157863584245 33456.348099813826 30717.136840253148 29169.90210864224 24634.546151651404 29509.502859703945 29726.52632631227 1.1267755602615888 0.9615351792423161 0.9354041061603118 1.111907846236559 1.1254711610956079 1.0333241261715818 0.9812751677892033 0.8287058461266049 0.9926993331065317 1.0 14.85946326746381 -7.405735435181032 3.762957558052035 0.9291214730077193 1.0460547955446449 0.2945234283387287 0.07508017113466021 0.29943849161882746 7.53124263055692 0.035361168170010164 0.022576886765278387 3.928842008933726e-08 7.405735435181032 0.11693332253692557 GSDALS(ph)ETSSVSHIEDLEK ddPTM_PC-9_AZD4547_30min_R2 2 GSDALSETSSVSHIEDLEK 19 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 GS(0.019)DALS(0.824)ET(0.116)S(0.038)S(0.003)VSHIEDLEK;GS(0.021)DALS(0.459)ET(0.284)S(0.089)S(0.135)VS(0.013)HIEDLEK 101.05 0.00023518 35136000.0 77359.0 73579.0 207957.0 214061.0 216611.0 180959.0 156730.0 272560.0 194598.0 202900.0 True False 101957.552832841 97361.9728342325 205199.35430331022 164712.543659482 186538.3016280255 169643.6051234623 170678.66637375834 230442.11480571466 204884.05300030907 195796.53275795313 0.5207321671976827 0.4972609650580123 1.0480234323504647 0.8412434139633226 0.95271504045798 0.8664280349293952 0.8717144474910293 1.1769468619272792 1.0464130805298277 1.0 17.578995691793146 -5.256279845525746 24.994764642194465 0.9685536011171797 0.5089965060367185 0.7883835752068316 0.09661047832291399 191.66934965990015 928512.5411970422 0.02664289551478927 0.06613139873350916 5.542684449395425e-06 5.256279845525746 -0.45955709508046116 GSDALS(ph)ETSSVSHIEDLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GSDALSETSSVSHIEDLEK 19 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 GSDALS(1)ETSSVSHIEDLEK;GS(0.021)DALS(0.589)ET(0.23)S(0.116)S(0.036)VS(0.008)HIEDLEK;GS(0.048)DALS(0.373)ET(0.268)S(0.118)S(0.148)VS(0.046)HIEDLEK;GS(0.03)DALS(0.352)ET(0.352)S(0.13)S(0.13)VS(0.005)HIEDLEK 202.96 3.6320999999999996e-17 40280900.0 56940.9 84544.6 138769.0 164702.0 197876.0 165554.0 160334.0 131440.0 154569.0 110193.0 True False 66579.86973596152 92937.62915220359 142077.77924436302 155474.2809110882 159103.61826475093 156872.0567988394 145146.0028023628 127989.83927219149 156829.2792091816 130170.11861269173 0.5114835143852278 0.7139705344260328 1.0914776813494451 1.1943930186749425 1.2222745124643233 1.2051310889989786 1.1150485560686192 0.9832505388814506 1.2048024606615868 1.0 16.990038781028197 -5.145490508148109 2.4835694234221677 1.1397394592741361 0.5203485580767241 0.8730297411819882 0.08028993435019646 0.10353567486252613 1.163149409656848 0.022644214816500443 0.09504092597585226 7.153350281214143e-06 5.145490508148109 -0.619390901197412 GSDALS(ph)ETSSVSHIEDLEK ddPTM_PC-9_Lapatinib_30min_R1 1 GSDALSETSSVSHIEDLEK 19 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 GSDALS(0.775)ET(0.142)S(0.039)S(0.039)VS(0.004)HIEDLEK 180.32 4.6373e-09 2445300.0 6702.5 5648.6 9678.9 7510.0 10203.0 10055.0 8274.0 8125.7 10316.0 6654.2 True False 6606.9211209120385 5635.521013748951 8883.13820363445 8062.310452625587 9602.879599869793 9624.971089349816 8702.387235007078 8503.24968632626 9154.103447704116 7804.369603835839 0.8465669178026556 0.7220981706170219 1.1382262315291163 1.033050824330894 1.2304491057355853 1.2332797622269391 1.1150660049121537 1.089549844249678 1.1729459152222728 1.0 12.930066388210571 -5.267238643580473 24.90912491456992 1.1335392469512777 0.7843325338972172 0.760585973493885 0.07672533592167463 178.22616403939656 765524.0333830352 0.019975145459075812 0.04347580733036479 5.4045726161041915e-06 5.267238643580473 -0.3492067130540605 GSDALSET(ph)SSVSHIEDLEK ddPTM_PC-9_AZD4547_30min_R2 1 GSDALSETSSVSHIEDLEK 19 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 GS(0.022)DALS(0.15)ET(0.582)S(0.119)S(0.119)VS(0.009)HIEDLEK 85.881 0.0026599 10248000.0 26366.0 27615.0 74259.0 78762.0 82750.0 70592.0 67060.0 98000.0 71407.0 71894.0 True False 34749.83955313128 36541.00870924223 73274.2771400314 60604.63776076973 71261.590868973 66177.87108060636 73028.21008756632 82856.35181596744 75181.4282397202 69377.01294283036 0.5008840548059721 0.5267019601918231 1.0561751512768724 0.8735550175778042 1.0271642990408885 0.9538875813973104 1.0526283417209774 1.194291139116131 1.0836648199551764 1.0 16.082170105654633 -5.258677021480926 24.19054918823254 1.0294866339254574 0.5137929021736325 0.872076515085769 0.0791085601274786 51.10619310223132 447537.08524202014 0.02249733937951905 0.05423514178626292 5.512174764702494e-06 5.258677021480926 -0.5156937317518249 GSDALSET(ph)SSVSHIEDLEK ddPTM_PC-9_Lapatinib_30min_R1 4 GSDALSETSSVSHIEDLEK 19 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 GS(0.002)DALS(0.324)ET(0.656)S(0.017)S(0.001)VSHIEDLEK;GS(0.007)DALS(0.211)ET(0.614)S(0.064)S(0.101)VS(0.003)HIEDLEK;GS(0.063)DALS(0.325)ET(0.43)S(0.071)S(0.081)VS(0.03)HIEDLEK;GS(0.012)DALS(0.1)ET(0.293)S(0.293)S(0.293)VS(0.01)HIEDLEK 88.765 0.0023 43516100.0 210651.0 165652.0 302308.0 214004.0 264375.0 273916.0 210259.0 249805.0 319806.0 210999.0 True False 207647.07811133747 165268.44297162883 277453.40318262676 229742.568056416 248824.9822812483 262201.2512093826 221145.18221481156 261411.85225798827 283786.0805735229 247469.89601150542 0.8390801526084752 0.6678325147231045 1.1211602205131541 0.9283657194640546 1.0054757620687724 1.0595278675721926 0.8936245813289954 1.0563379888672788 1.1467499083619006 1.0 17.91689351067381 -5.259496045992447 24.999931501331233 1.0206092178936972 0.7534563236008093 0.6336442216034428 0.0829239483980473 101.76909105656883 1309178.778327427 0.02086344949316995 0.04987088871943453 5.501789295583333e-06 5.259496045992447 -0.2671528942928879 GSDALSETS(ph)SVSHIEDLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSDALSETSSVSHIEDLEK 19 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 GSDALS(0.001)ET(0.002)S(0.604)S(0.392)VS(0.001)HIEDLEK 105.46 0.00013593 6747500.0 26770.0 30207.0 33990.0 43790.0 56462.0 39368.0 46758.0 43001.0 44594.0 36090.0 True False 31301.63226839912 33205.75132889172 34800.45050779284 41336.58826909549 45398.676415858354 37303.47277659685 42328.74374139539 41872.26931332561 45246.102886440545 42632.8313117172 0.7342142500349533 0.7788774591605755 0.816282884271594 0.9695951921854777 1.0648759422971044 0.8749940275804382 0.9928672912174558 0.9821601808983642 1.061297162171003 1.0 15.379677249623393 -5.692461184621781 2.8897171840074174 0.9918567346180964 0.7617330487831444 0.8002140695213422 0.05010037724489994 0.11230392310172657 1.891058481526696 0.01460479632499325 0.027234771841893705 2.0301999623169345e-06 5.692461184621781 -0.23012368583495202 GSDALSETSS(ph)VSHIEDLEK ddPTM_PC-9_AZD4547_30min_R2 2 GSDALSETSSVSHIEDLEK 19 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 GSDALSETS(0.027)S(0.972)VSHIEDLEK;GSDALSETS(0.009)S(0.987)VS(0.005)HIEDLEK 175.85 6.6876e-09 20655000.0 103683.0 89282.0 162265.0 148998.0 161480.0 173957.0 150479.0 163809.0 147990.0 172783.0 True False 136652.03725962664 118140.66049533109 160113.26007793256 114648.81309615256 139061.28934769475 163079.4412903599 163871.3394835505 138496.0830063445 155812.44927242707 166733.91976105236 0.8195815072029957 0.7085580466448541 0.9602920647903683 0.6876154129912896 0.8340311890165153 0.9780819735064723 0.9828314461652179 0.8306413188439659 0.9344976084993568 1.0 17.347188105414112 -6.621138728280906 5.518060607134263 0.9361773293176998 0.7953533992772271 0.4396280173726993 0.08138797276845358 0.21023400734757242 9.767330846837067 0.026546719586932766 0.026508599620032984 2.392551372857464e-07 6.621138728280906 -0.14082393004047267 GSDALSETSS(ph)VSHIEDLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSDALSETSSVSHIEDLEK 19 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 GSDALSET(0.002)S(0.06)S(0.935)VS(0.003)HIEDLEK;GSDALSET(0.002)S(0.043)S(0.944)VS(0.012)HIEDLEK 115.85 4.0394e-05 25834000.0 106606.0 128671.0 149174.0 156617.0 189754.0 145925.0 177145.0 125633.0 149236.0 150710.0 True False 124652.29023552289 141444.6065229854 152730.87390554554 147842.2572491652 152573.06586048618 138272.43611371896 160364.5431812625 122335.26686916647 151418.29417322573 178032.5299802967 0.700165808177407 0.794487426194749 0.8578818372263127 0.8304227169356481 0.85699543716742 0.7766695003942364 0.9007597836137612 0.6871512014276583 0.8505091411664125 1.0 17.441781347951 -12.385408258532571 1.334009325356147 3.7170634995871996 0.807924134519055 0.4390070484986842 0.06572391283781077 308491.08369592833 8790.781851622925 2527255.5126728476 0.01826565963207349 4.1171030884690763e-13 12.385408258532571 -2.9091393650681447 GSDALSETSS(ph)VSHIEDLEK ddPTM_PC-9_Lapatinib_30min_R1 3 GSDALSETSSVSHIEDLEK 19 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 GSDALSETS(0.026)S(0.972)VS(0.002)HIEDLEK;GSDALS(0.001)ET(0.006)S(0.077)S(0.908)VS(0.007)HIEDLEK;GSDALS(0.001)ET(0.019)S(0.072)S(0.894)VS(0.015)HIEDLEK 140.73 0.00010218 26532500.0 195217.0 150647.0 156292.0 156964.0 157540.0 184316.0 152408.0 142911.0 168075.0 128515.0 True False 192433.16978158677 150298.18612722415 143442.27506456675 168507.65617655407 148273.80693555705 176433.2343415814 160298.94050192868 149551.16678225523 149144.62359178654 150728.6465145264 1.2766861126364664 0.9971441368495221 0.951659013608555 1.117953753802959 0.9837135167353025 1.170535518107885 1.06349353098238 0.9921880826272949 0.9894908966585381 1.0 17.20159410674689 -4.756173670141987 24.998251510170583 1.0336899554379038 1.2766864927319344 0.565619929960893 0.0648757698657446 128.9114341166956 611923.1475919202 0.016417011943289518 0.13589946684451373 1.753179282291514e-05 4.756173670141987 0.2429965372940306 GSDDAPYS(ph)PTAR ddPTM_PC-9_AZD4547_30min_R2 1 GSDDAPYSPTAR 12 0 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 GSDDAPYS(0.5)PT(0.5)AR 110.15 0.0012272000000000001 16813000.0 48161.0 56427.0 66759.0 89047.0 71491.0 61160.0 52667.0 62220.0 55207.0 60919.0 True False 63475.19618896899 74665.92425987369 65873.73204044436 68518.58991243567 61565.70867448623 57335.65553164508 57354.26097050176 52605.32867336206 58125.129312675715 58786.24435230052 1.0797627385169908 1.2701257765746645 1.1205637095247858 1.1655548107786933 1.047280862263094 0.9753243494862133 0.9756408425546457 0.8948577894873365 0.9887539160409227 1.0 15.843190991645582 -6.479376634440586 1.7991828165007906 0.9566492973589407 1.1695738926760935 0.7447262139114499 0.05276733848722495 0.159039447927783 1.0337160733918058 0.018774757876305087 0.021118944553956413 3.316067525484655e-07 6.479376634440586 0.2129245953171528 GSDDAPYS(ph)PTAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSDDAPYSPTAR 12 0 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 GSDDAPYS(0.896)PT(0.104)AR 97.463 0.0039631 12089000.0 48272.0 58901.0 67612.0 60665.0 91806.0 56438.0 52138.0 66377.0 45139.0 54242.0 True False 56443.49618454099 64748.30201685214 69224.12649993804 57266.13672858367 73817.27333488515 53478.291926579244 47199.111193568475 64634.67408224488 45799.07248040185 64075.64522056427 0.8808884559843053 1.010497854433965 1.0803500497209417 0.8937270398364217 1.1520332425961186 0.8346118364082592 0.7366154649102232 1.0087245139671446 0.7147656855073418 1.0 15.96748848060156 -6.809801355246196 24.999807766353126 0.8518430284953036 1.0020596879118544 0.27942928556462465 0.11577476697766821 144.91232474003073 74908.62158014432 0.03842201544741407 0.033885101458480046 1.549525204173822e-07 6.809801355246196 0.15021665941655082 GSDDAPYS(ph)PTAR ddPTM_PC-9_Lapatinib_30min_R1 1 GSDDAPYSPTAR 12 0 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 GS(0.001)DDAPYS(0.696)PT(0.303)AR 118.73 0.00057132 17391000.0 107630.0 121850.0 113530.0 101500.0 101070.0 108580.0 106350.0 102480.0 108750.0 67719.0 True False 106095.17646307514 121567.86381144164 104196.00163847323 108964.64859407407 95125.26131126542 103936.2865123425 111856.28262545355 107241.59492163348 96501.42981173153 79424.13892010438 1.3358051834820661 1.5306160754695894 1.3118933746740116 1.3719336473220762 1.1976870332450864 1.3086233974396093 1.4083411434648834 1.3502393148953329 1.215013862584092 1.0 16.277289923538525 -13.711804099415387 0.17596164521140606 4.834829321341819e-20 1.4205981484938721 0.6324792704263623 0.08172206024741203 66.08322278100361 0.8152452204449406 23.52896694401459 0.290206480085494 1.9417615655450255e-14 13.711804099415387 1.4205981484938721 GSDFDCELR ddPTM_PC-9_AZD4547_30min_R2 3 GSDFDCELR 9 0 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 ;; 134.77 0.0050525 97647000.0 134710.0 114139.0 178611.0 261435.0 234958.0 194566.0 158933.0 216791.0 159683.0 203457.0 False True 177544.97785793513 151032.1996402026 176242.5014376457 201165.1998804859 202338.137370298 182399.75726242777 173077.72910598243 183290.932311585 168123.51738069422 196334.03235749112 0.9043005724787219 0.7692614358635413 0.897666590562037 1.0246068777021704 1.0305810711505912 0.9290277140048171 0.8815472642605187 0.9335667897751072 0.8563136780819012 1.0 17.582950744326013 -5.519534155000074 24.897795526230368 0.948612562291859 0.8359517439438265 0.35540023341659277 0.061547201810524005 134.75243731622095 1003123.0940616598 0.017452611951257024 0.031047766860968468 3.0231928027865968e-06 5.519534155000074 -0.11266081834803243 GSDFDCELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GSDFDCELR 9 0 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 ;;; 129.42 0.005982899999999999 100981000.0 161206.0 172248.0 219920.0 205449.0 235635.0 213524.0 220774.0 188274.0 193289.0 146654.0 False True 188494.9918363672 189347.64309262545 225163.72685124452 193938.35860464486 189464.01327000055 202326.42555248082 199860.6884546566 183332.0069927922 196115.48595813793 173241.20928757463 1.0880493885463003 1.0929711462491276 1.2997122784884296 1.1194701272415712 1.093642869667901 1.1678885548335425 1.1536555838910967 1.0582470980589103 1.1320371565439304 1.0 17.402422622533884 -9.025254506160108 0.5282580011599277 0.9942320461893589 1.149746251297073 0.3059108914899159 0.06263600012573788 2.4118357145755582 1.2058885531027768 0.09971811105168853 0.03169114385807111 9.435077978317186e-10 9.025254506160108 0.1555142051077142 GSDFDCELR ddPTM_PC-9_Lapatinib_30min_R1 3 GSDFDCELR 9 0 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 ;; 172.25 0.0019268 111622000.0 502460.0 562400.0 643790.0 565990.0 592870.0 637610.0 520670.0 520520.0 603030.0 530160.0 False True 495294.82826012024 561097.7973537529 590860.071301265 607614.7926872921 557998.5522272664 610340.9066415064 547627.7449421235 544705.2594516834 535110.4112125834 621797.4496062046 0.7965533286985967 0.9023803454149033 0.9502452473477774 0.9771908731245285 0.8973960130918143 0.9815751206892953 0.8807172581504571 0.8760171978779503 0.860586371898885 1.0 19.246085173701786 -4.778023213485587 3.6686204840918593 0.9245707697724872 0.7820869728744484 0.41637348736784174 0.04637337295037633 0.2791673355335573 6.458428370195157 0.011961576160348073 0.10989465155586196 1.6671580988588063e-05 4.778023213485587 -0.1424837968980388 GSDIDNPTLTVMDIS(ph)PPSR ddPTM_PC-9_AZD4547_30min_R2 1 GSDIDNPTLTVMDISPPSR 19 0 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 GSDIDNPTLTVMDIS(0.991)PPS(0.008)R 100.27 0.0027886 0.0 6165.9 6827.1 7483.5 9274.2 9069.0 9408.2 7921.0 7909.4 8557.9 7179.4 True False 8126.527941312757 9033.826563782995 7384.2639003679615 7136.17647496166 7809.925892334922 8819.903766723737 8625.953654989737 6687.18396993073 9010.253122700875 6928.0513912392835 1.172988980940439 1.3039491270527415 1.065850046912985 1.0300409266573218 1.1272904098561962 1.273071354216101 1.2450764533729497 0.9652330204113184 1.3005465193423067 1.0 12.758233916460425 -11.184763360046674 2.721663119830918 0.9807219869758542 1.160666230978873 0.16241469428785082 0.11196852163606236 25731795.69467648 23536060.260842077 3465497.9166252892 0.027709451300543735 6.53486529767413e-12 11.184763360046674 0.17994424400301867 GSEDS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSEDSPPK 8 0 P48651;P48651-2;P48651-3 P48651 PTDSS1 Phosphatidylserine synthase 1 1 GSEDS(1)PPK 84.81700000000001 0.013691 15144000.0 214960.0 381860.0 232480.0 148750.0 339100.0 138460.0 219330.0 121580.0 117280.0 160660.0 True False 251348.48234647248 419768.53717517765 238023.20488530997 140416.0197540068 272655.7892497185 131198.91385510037 198553.47458831116 118388.65382465838 118994.99812803848 189786.3862161396 1.3243757223988788 2.2117947738207167 1.2541637449918854 0.7398634989239586 1.4366456661396274 0.6912978136676439 1.0461945060811007 0.6237995052491837 0.6269943830034267 1.0 17.53401698290292 -5.499921810284201 5.484037984983795 0.8924194854624993 1.7688941342062792 0.5724409938167396 0.30554178004610505 0.11683040824551391 10.754307690122465 0.07920532259037139 0.15806380458619446 3.162847043066632e-06 5.499921810284201 0.8764746487437799 GSEDS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 1 GSEDSPPK 8 0 P48651;P48651-2;P48651-3 P48651 PTDSS1 Phosphatidylserine synthase 1 1 GS(0.001)EDS(0.999)PPK 75.652 0.026068 21921000.0 40129.0 100690.0 25379.0 21749.0 29292.0 28670.0 39702.0 31778.0 35173.0 10944.0 True False 39556.75310124267 100456.85849137536 23292.436585773037 23348.49401253713 27569.102150287752 27443.850933034246 41757.57529662206 33254.521891292556 31211.446351889976 12835.655818036634 3.081786677830486 7.826390791050475 1.814666653264616 1.8190339740746149 2.1478530229478197 2.138094953782588 3.2532482865382235 2.5907925829986325 2.4316206974038463 1.0 13.64786938962389 -5.285884759259007 24.995705467414346 2.2333909952325985 5.454089144201453 0.5483170830513595 1.1978084758920453 459.6012274602429 469947.27347438905 0.29045086566917233 0.6050739970894286 5.1774419798231455e-06 5.285884759259007 3.2206981489688546 GSEEDPLLS(ph)PVETWK ddPTM_PC-9_AZD4547_30min_R2 2 GSEEDPLLSPVETWK 15 0 A0A0A0MSK6;Q13017-2;Q13017;H0YK04 A0A0A0MSK6 ARHGAP5 Rho GTPase-activating protein 5 1 GSEEDPLLS(0.996)PVET(0.004)WK;GSEEDPLLS(0.998)PVET(0.002)WK 103.6 0.0012533 2622400.0 11765.7 13941.8 15491.6 19121.9 18179.1 18312.7 17264.0 19669.7 14258.9 13485.900000000001 True False 15506.947858237 18448.214203241463 15286.171261968384 14713.641385410001 15655.24575910749 17167.603974073863 18800.46255520045 16630.199829740122 15012.596343878711 13013.76274578849 1.1915806489752823 1.4175926335534024 1.174615794107303 1.1306216098162405 1.2029761157413015 1.3191883323391336 1.4446600051383793 1.2778932699631382 1.153593825024748 1.0 13.667750536826313 -8.546599240498416 2.9810926480510096 1.000994793748901 1.2716112615683066 0.4304229120910886 0.09705782920572596 0.26098512181693756 5.936716374886219 0.1007339857706965 0.02687772223795581 2.8405390201184555e-09 8.546599240498416 0.2706164678194056 GSEEDPLLS(ph)PVETWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GSEEDPLLSPVETWK 15 0 A0A0A0MSK6;Q13017-2;Q13017;H0YK04 A0A0A0MSK6 ARHGAP5 Rho GTPase-activating protein 5 1 GSEEDPLLS(1)PVETWK;GSEEDPLLS(0.996)PVET(0.004)WK;GSEEDPLLS(1)PVETWK 174.24 1.7315e-21 1754300.0 19011.9 22916.6 17816.9 19573.0 28050.5 24711.5 32799.0 25003.300000000003 23990.5 20790.800000000003 True False 22230.239167858683 25191.608597466824 18241.72246696952 18476.388266522175 22554.205887199078 23415.585437890473 29692.041275803665 24346.98986818618 24341.31567693303 24560.007460117773 0.9051397563277483 1.0257166508753992 0.7427409171838275 0.7522957106802758 0.9183305796557328 0.9534030262781601 1.208958968111864 0.9913266479141953 0.9910956141385596 1.0 14.584023378477138 -6.859651890170611 3.0253507913311832 1.0495600142390409 0.8614934339599188 0.42658133198154646 0.09689994358567595 0.25802519232504223 4.741739507776608 0.03884338042893199 0.03417757826381359 1.3814911586240603e-07 6.859651890170611 -0.18806658027912204 GSEEDPLLS(ph)PVETWK ddPTM_PC-9_Lapatinib_30min_R1 3 GSEEDPLLSPVETWK 15 0 A0A0A0MSK6;Q13017-2;Q13017;H0YK04 A0A0A0MSK6 ARHGAP5 Rho GTPase-activating protein 5 1 GSEEDPLLS(1)PVETWK;GSEEDPLLS(1)PVETWK;GS(0.002)EEDPLLS(0.988)PVET(0.01)WK 126.48 0.00036469 0.0 16013.2 16243.0 20734.3 16683.7 23493.4 22408.0 28356.2 30396.1 26357.3 22867.6 True False 15784.848831538766 16205.390331466939 19029.605890712563 17910.674953191672 22111.56440180154 21449.66207559927 29824.34528804782 31808.41377241857 23388.66331932644 26820.234190838313 0.588542542888414 0.6042225513825914 0.709524225452625 0.6678045697046855 0.8244359182126294 0.799756703203076 1.1120091299663484 1.1859856832750626 0.872052911727218 1.0 14.711034214274534 -6.772748559094531 1.2595384443841187 1.0559402364523027 0.6357791882213297 0.7710795324749735 0.094190793867331 0.20304191009190217 0.6771895861981254 0.04709933257462548 0.042025844166360245 1.6875297617309872e-07 6.772748559094531 -0.420161048230973 GSEGSQS(ph)PGSSVDDAEDDPSR ddPTM_PC-9_Lapatinib_30min_R1 1 GSEGSQSPGSSVDDAEDDPSR 21 0 Q8IX07 Q8IX07 ZFPM1 Zinc finger protein ZFPM1 1 GSEGS(0.003)QS(0.981)PGS(0.008)S(0.008)VDDAEDDPSR 151.64 4.9229e-05 5957400.0 10381.0 11318.0 13752.0 11875.0 15221.0 11571.0 10034.0 8382.7 10766.0 11828.0 True False 10232.965036357751 11291.793866375845 12621.363644255138 12748.327113838737 14325.730705637385 11076.135303318424 10553.511423260934 8772.190844550893 9553.419708994039 13872.454040180684 0.7376463462570224 0.8139723392609468 0.9098147744947043 0.9189669741859671 1.032674584045751 0.7984265272198487 0.7607530284615366 0.632346001590115 0.6886611180201545 1.0 13.759935402858318 -6.991307453491104 24.94791344307915 0.7454861224261481 0.8856540231559235 0.16776442423847648 0.11462688887399869 279.6397593049742 802571.5463975519 0.04102705443842168 0.036129382449292376 1.0202169778045176e-07 6.991307453491104 0.14016790072977536 GSEGYLAATYPT(ph)VGQTSPR ddPTM_PC-9_AZD4547_30min_R2 1 GSEGYLAATYPTVGQTSPR 19 0 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 GSEGYLAAT(0.017)Y(0.008)PT(0.401)VGQT(0.26)S(0.314)PR 67.456 0.022362 55299000.0 24784.0 22839.0 30160.0 51014.0 42165.0 29504.0 34798.0 51425.0 32495.0 39361.0 True False 32664.79646077546 30221.26010901262 29760.058693806088 39253.510458443234 36311.11757087905 27659.110215919845 37894.95458734162 43478.44787893999 34212.61936014269 37982.983370555965 0.8599850133440778 0.7956526167041381 0.7835102999538418 1.033449902433735 0.9559838208766683 0.7281974126698251 0.9976824152448598 1.1446822766598175 0.9007354431949118 1.0 15.213065605860173 -6.418992137020729 0.4472312304502174 1.0221584072227499 0.7932064618384181 0.24371930471913061 0.10719407877392638 2.1215963409345986 0.822572287019536 0.10544424416728476 0.2169654083347674 3.8107272272111783e-07 6.418992137020729 -0.22895194538433172 GSEGYLAATYPT(ph)VGQTSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSEGYLAATYPTVGQTSPR 19 0 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 GSEGYLAAT(0.031)Y(0.007)PT(0.391)VGQT(0.285)S(0.285)PR 110.34 0.0011403 0.0 3367.7 4838.9 7344.0 5187.3 7813.2 7842.9 7454.9 7416.0 6536.3 5324.1 True False 3937.7850948930777 5319.274012823987 7519.108812275094 4896.672398453506 6282.259547525497 7431.604517363624 6748.717903197927 7221.337857901507 6631.881022035279 6289.31718444759 0.6261069332980295 0.8457633566291815 1.195536588752205 0.778569796187437 0.9988778373366912 1.1816234257894824 1.0730446096575248 1.1481910748210704 1.0544675721610592 1.0 12.61868768044964 -4.396922629319421 1.1234917881595372 1.0618615429123641 3.9009765459739793e-16 0.561482949405865 0.11718340026800599 2.6239958286889506 1.547691902681845 0.03698156551715595 4.053734721461034 4.009381394273753e-05 4.396922629319421 -1.0618615429123637 GSEGYLAATYPTVGQT(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 GSEGYLAATYPTVGQTSPR 19 0 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 GSEGYLAAT(0.009)Y(0.007)PT(0.039)VGQT(0.473)S(0.473)PR 64.327 0.027806 12154000.0 27717.0 30076.0 26383.0 25643.0 26036.0 20752.0 19854.0 18508.0 26794.0 14356.0 True False 27321.7504973247 30006.360869863944 24213.891581325115 27528.871762540348 24504.613668745456 19864.485335274734 20881.942973631907 19367.94924677585 23776.177566671573 16837.415471832424 1.6226807815624484 1.7821239203880224 1.4381002608050453 1.63498203204606 1.455366692693401 1.1797823346763845 1.2402107086188872 1.1502922927320285 1.4121037522918594 1.0 14.039383082554071 -6.571371495995552 2.7113576219116324 1.206552617967895 1.6185411392065132 0.7241623288844286 0.12330031682757592 0.14748951569259436 2.2024662209131507 0.04228488368036954 0.043822403484682006 2.68304838112258e-07 6.571371495995552 0.4119885212386183 GSEGYLAATYPTVGQTS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 GSEGYLAATYPTVGQTSPR 19 0 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 GSEGYLAATYPT(0.004)VGQT(0.156)S(0.841)PR;GSEGYLAAT(0.007)Y(0.005)PT(0.039)VGQT(0.308)S(0.641)PR;GSEGYLAATYPTVGQT(0.098)S(0.902)PR 135.95 8.3289e-05 77547200.0 213856.0 268586.0 393254.0 501611.0 469499.0 377153.0 410240.0 477654.0 380866.0 419956.0 True False 281857.75951886637 355401.1720145037 388039.19501240103 385972.3337626957 404317.16799265123 353569.56328853103 446750.56525981496 403843.54969697987 400997.79920665 405253.46826465835 0.6955098021142508 0.8769848991949954 0.9575222062232538 0.9524220370413444 0.9976895934388508 0.8724652371330869 1.1023978824236889 0.9965208969741434 0.9894987473488343 1.0 18.62846500719212 -4.102425039758159 0.9040286648772532 0.9929118344142659 8.383704549010985e-12 0.7463747354816778 0.052226880220725726 3.1792260054839048 0.8493100368879551 0.017596193900053965 4.176141156888082 7.89905177112645e-05 4.102425039758159 -0.9929118344058822 GSEGYLAATYPTVGQTS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GSEGYLAATYPTVGQTSPR 19 0 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 GSEGYLAATYPTVGQT(0.426)S(0.574)PR;GSEGYLAATYPT(0.001)VGQT(0.224)S(0.775)PR;GSEGYLAATYPTVGQT(0.319)S(0.681)PR;GSEGYLAATYPTVGQT(0.015)S(0.985)PR;GSEGYLAATYPT(0.001)VGQT(0.091)S(0.908)PR 214.94 1.0794e-27 104144000.0 350133.6 411635.1 513234.2 522706.4 619067.0 541075.0 532344.4 501974.6 463741.0 433615.7 True False 409404.30302617635 452499.5123263979 525471.6497795433 493420.85504501284 497765.2653596428 512700.07449190074 481916.88459230243 488798.29863605375 470522.334813223 512226.79391000775 0.7992637399950302 0.8833968033423428 1.0258574054051974 0.9632859134106544 0.9717673329035075 1.0009239668590553 0.9408271693748406 0.9542614803588934 0.9185820429688187 1.0 18.966423194826447 -4.991915432839635 3.774109789477435 0.9697750592565795 0.8068234438888949 0.7694698976264048 0.030202665683348423 0.09973743153066027 3.0961579035130775 0.007851468230962465 0.033887560719645445 1.0187897506215847e-05 4.991915432839635 -0.16295161536768454 GSEGYLAATYPTVGQTS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 GSEGYLAATYPTVGQTSPR 19 0 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 GSEGYLAATYPTVGQT(0.007)S(0.993)PR;GSEGYLAATYPTVGQT(0.011)S(0.988)PR;GSEGYLAATYPTVGQT(0.002)S(0.997)PR 290.67 1.2852999999999996e-106 115633900.0 386450.0 358226.0 332897.0 294318.0 299259.0 304707.0 257529.0 247210.0 331261.0 173215.0 True False 380939.1521337499 357396.5497063396 305527.4936795809 315963.1275360658 281657.1739858308 291675.39191670995 270862.5915209255 258696.27908447478 293950.89784702513 203154.98195552087 1.8751159753352908 1.759231037635044 1.5039133706623729 1.5552812168064054 1.3864152937558645 1.4357284724652724 1.333280576797416 1.2733937243100157 1.4469293099166196 1.0 17.632221218549965 -1.5228787452803376 0.15960740727351724 1.0287862996586825 4.195155497480317 0.8606886262678127 0.08684871908308185 22.501609199477738 0.23263102019486648 0.26131144934490275 16.734617464795672 0.029999999999999995 1.5228787452803376 3.1663691978216346 GSEMDNNCS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 1 GSEMDNNCSPTR 12 0 O95243-3;O95243-5;O95243-2;O95243 O95243-3 MBD4 Methyl-CpG-binding domain protein 4 1 GSEMDNNCS(0.995)PT(0.005)R 69.352 0.028485000000000003 4986700.0 15280.0 19242.0 20611.0 25139.0 19027.0 19801.0 16137.0 21940.0 14287.0 19914.0 True False 20138.72215625601 25461.60020218139 20337.68467301184 19343.591943678286 16385.42947992684 18562.840339798953 17573.161738488758 18549.677131044104 15042.181652511412 19216.816921349862 1.0479738782275598 1.324964498875648 1.0583274408165224 1.0065970874805794 0.8526609556092843 0.9659685272421812 0.9144678752163682 0.965283543417403 0.7827613550191845 1.0 14.230081767061222 -5.706765759730071 2.287221685203613 0.9165816904562589 1.1863499446074475 0.5829271368428568 0.08884867098684393 0.18501435198951438 1.96667789658577 0.02448986985710369 0.04840162487143852 1.9644195168392325e-06 5.706765759730071 0.26976825415118855 GSEMDNNCS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 1 GSEMDNNCSPTR 12 0 O95243-3;O95243-5;O95243-2;O95243 O95243-3 MBD4 Methyl-CpG-binding domain protein 4 1 GSEMDNNCS(0.993)PT(0.007)R 68.171 0.030951 1501000.0 5414.9 10941.0 10604.0 9139.1 9811.1 11700.0 12107.0 10776.0 9769.5 6826.1 True False 5337.682533028955 10915.666786713042 9732.180052623724 9811.219901143879 9234.030387364752 11199.618274032118 12733.841219994036 11276.692299722086 8669.156032604242 8005.982289793481 0.6667117587599165 1.3634387875962461 1.215613487558036 1.225486086029921 1.1533913082891605 1.3989062014676301 1.5905407680239214 1.4085332557003414 1.0828347751476062 1.0 12.966862708974176 -4.75738310147811 24.99979463711668 1.2908970556898256 0.6667108529840461 0.5396154591348103 0.16652868731309647 93.46132421907339 575945.920256268 0.04253290205038869 0.31714233513300055 1.7483037879119446e-05 4.75738310147811 -0.6241862027057795 GSEMDNNCS(ph)PTRK ddPTM_PC-9_AZD4547_30min_R2 2 GSEMDNNCSPTRK 13 1 O95243-3;O95243-5;O95243-2;O95243 O95243-3 MBD4 Methyl-CpG-binding domain protein 4 1 GSEMDNNCS(0.993)PT(0.007)RK;GSEMDNNCS(0.991)PT(0.009)RK 82.515 0.010029000000000001 11447700.0 18757.0 21027.0 28367.0 31879.0 31309.0 27361.0 23493.0 28044.0 24002.0 26467.0 True False 24721.33583016322 27823.56654460387 27990.83504533146 24529.78907564025 26962.285782678784 25650.11234469164 25583.83148802854 23710.44418701006 25270.696718945837 25540.398385927823 0.9679307055673851 1.0893943831328026 1.0959435566499922 0.9604309496266746 1.055672091533795 1.0042957027179444 1.0017005647854205 0.9283506008298592 0.9894401934180249 1.0 14.640493408306604 -7.188952774669393 1.8446379267548345 0.9700776944757905 1.0366468062572807 0.23216229311058356 0.04577475731994452 0.4755685694281504 3.171955500284931 0.023173963172486663 0.01535438031783976 6.472129900843106e-08 7.188952774669393 0.06656911178149016 GSEMDNNCS(ph)PTRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSEMDNNCSPTRK 13 1 O95243-3;O95243-5;O95243-2;O95243 O95243-3 MBD4 Methyl-CpG-binding domain protein 4 1 GSEMDNNCS(0.994)PT(0.006)RK 100.18 0.0022305 4535500.0 14448.0 14215.0 13112.0 15697.0 17038.0 15106.0 15981.0 18376.0 14650.0 12336.0 True False 16893.761038992536 15626.171256337808 13424.639807536909 14817.547980360636 13699.526208306383 14313.81476740683 14467.163987579448 17893.649470981414 14864.22853492294 14572.419148277737 1.159296947685529 1.072311405356784 0.921236183981403 1.0168214233744346 0.9400996546222377 0.982253846925514 0.9927770976371669 1.2279120775287473 1.0200247730782361 1.0 13.830952776753833 GSEMDNNCS(ph)PTRK ddPTM_PC-9_Lapatinib_30min_R1 2 GSEMDNNCSPTRK 13 1 O95243-3;O95243-5;O95243-2;O95243 O95243-3 MBD4 Methyl-CpG-binding domain protein 4 1 GSEMDNNCS(0.983)PT(0.016)RK;GS(0.002)EMDNNCS(0.997)PT(0.001)RK 93.348 0.0040076 6239700.0 13430.9 21376.3 23871.8 20935.5 20743.2 19557.1 23622.8 19124.9 22956.0 16848.0 True False 13239.372903074585 21326.80449070595 21909.152751812806 22475.16650878069 19523.1257587003 18720.688422826785 24845.8729967519 20013.512672880006 20370.453542603293 19760.15435145114 0.670003516551596 1.0792832946236455 1.1087541302633523 1.137398327413883 0.9880047195717662 0.9473958598634115 1.2573724149542018 1.012821677246173 1.0308853453418159 1.0 14.27030659576371 -4.7603456274395395 24.999995655844707 1.0667967240145333 0.6700030455416073 0.6567543624751693 0.08505851534556927 16.652184678723373 380447.47814575926 0.021162196096456885 0.12615856486477536 1.736418373440926e-05 4.7603456274395395 -0.396793678472926 GSES(ph)PNSFLDQESR ddPTM_PC-9_AZD4547_30min_R2 1 GSESPNSFLDQESR 14 0 Q5T4Y8;A0A5H1ZRR2;G9CGD6-3;G9CGD6;G9CGD6-2;Q6P9H4 Q5T4Y8 CNKSR3 Connector enhancer of kinase suppressor of ras 3 1 GS(0.007)ES(0.808)PNS(0.185)FLDQESR 121.45 7.2101e-05 2877900.0 4500.3 3924.1 6975.5 8632.3 7608.4 7814.5 5154.7 9455.1 5766.2 7247.3 True False 5931.301787944957 5192.488585042094 6883.00031228927 6642.256602705518 6552.104990543725 7325.858079660575 5613.458314022929 7994.031551583189 6070.989560069385 6993.574232906437 0.8481073611883271 0.7424656423335289 0.9841892118486582 0.949765653655625 0.936875018744279 1.0475127360757341 0.802659430940229 1.143053792718659 0.8680810924268065 1.0 12.771814252448955 -5.268774597858531 24.93813000476279 0.9670099130953209 0.7952864996049134 0.36266137666812115 0.09079602842606806 474.6933783378247 1613857.5754001087 0.02176230699217621 0.04678749761903519 5.385492211392316e-06 5.268774597858531 -0.17172341349040754 GSES(ph)PNSFLDQESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSESPNSFLDQESR 14 0 Q5T4Y8;A0A5H1ZRR2;G9CGD6-3;G9CGD6;G9CGD6-2;Q6P9H4 Q5T4Y8 CNKSR3 Connector enhancer of kinase suppressor of ras 3 1 GS(0.087)ES(0.756)PNS(0.157)FLDQESR 112.03 0.00034291 3315300.0 3570.7 4640.3 5955.7 5226.4 4300.2 4008.0 6496.9 6348.5 5864.5 5092.3 True False 4175.148985460318 5100.958317325661 6097.706475118026 4933.581752217418 3457.6066792439883 3797.8134243192458 5881.466598517298 6181.858601791761 5950.257217956015 6015.493679375381 0.6940658918444487 0.8479700236099855 1.0136668410149807 0.8201457794116902 0.5747835279253437 0.6313386110503887 0.9777196871941523 1.027656071352344 0.9891552605826791 1.0 12.554467425980357 -7.390687331152765 6.990359529634722 1.0052622590113354 0.7732433353244161 0.500205547169394 0.11502145445434911 0.2587856596454525 13.53848766038676 0.055632305759590446 0.037265612096253814 4.067360520287596e-08 7.390687331152765 -0.23201892368691923 GSES(ph)PNSFLDQESR ddPTM_PC-9_Lapatinib_30min_R1 1 GSESPNSFLDQESR 14 0 Q5T4Y8;A0A5H1ZRR2;G9CGD6-3;G9CGD6;G9CGD6-2;Q6P9H4 Q5T4Y8 CNKSR3 Connector enhancer of kinase suppressor of ras 3 1 GS(0.141)ES(0.461)PNS(0.398)FLDQESR 99.055 0.0023004 3907100.0 6010.3 4713.2 8790.5 7243.2 7071.4 7943.0 4922.8 3860.8 7563.9 4110.0 True False 5924.592019845971 4702.2868749781455 8067.7790223112825 7775.889090606877 6655.474154907309 7603.296406037353 5177.678496554607 4040.186862543342 6711.973930601895 4820.4080237692415 1.2290644257979908 0.9754956119464068 1.6736713951452622 1.613118443970775 1.3806868883483365 1.5773138640019266 1.0741162306227354 0.8381420914207554 1.3924078413083325 1.0 12.234939553307038 -7.284470798123725 21.75687283308016 1.0626779705107865 1.4086828598753296 0.3347961782879988 0.22898570478943053 191.44276681706884 180845.71941336553 0.1004260480121111 0.06780376466938672 5.194325988794651e-08 7.284470798123725 0.3460048893645431 GSES(ph)PNSFLDQEYR ddPTM_PC-9_Lapatinib_30min_R1 1 GSESPNSFLDQEYR 14 0 A0A2R8Y604;A0A2R8YE27;A0A2R8YE71;A0A2R8Y7K8;A0A2R8Y5S6;A0A2R8Y622;A0A2R8YGJ7;A0A2U3TZH5;A0A2R8Y700;A0A2R8Y7A1;A0A2R8YED7;Q8WXI2-4;Q8WXI2-2;Q8WXI2-5;Q8WXI2 A0A2R8Y604 CNKSR2 Connector enhancer of kinase suppressor of ras 2 1 GS(0.004)ES(0.937)PNS(0.057)FLDQEY(0.002)R 103.77 0.005352399999999999 0.0 6285.8 6840.6 8639.1 5266.6 5806.5 6756.7 5706.1 4679.0 8040.9 4862.2 True False 6196.163339325458 6824.761010985211 7928.826545890384 5653.923332862575 5464.973086018228 6467.731691636986 6001.533937838272 4896.403421529293 7135.249167569218 5702.624791525741 1.0865458566611517 1.196775390365327 1.3903819444114298 0.9914598171116681 0.9583259088234825 1.1341674979648346 1.0524160640476854 0.858622757156579 1.2512219247130545 1.0 12.477410397290326 -5.790026222461254 24.99690269989955 1.0309238730800787 1.2217886854119693 0.34227393270834516 0.12019330331932665 221.96361803652366 194088.51143613248 0.033180610367181444 0.04922506458444799 1.6217121763161053e-06 5.790026222461254 0.19086481233189057 GSESPNSFLDQES(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSESPNSFLDQESR 14 0 Q5T4Y8;A0A5H1ZRR2;G9CGD6-3;G9CGD6;G9CGD6-2;Q6P9H4 Q5T4Y8 CNKSR3 Connector enhancer of kinase suppressor of ras 3 1 GS(0.179)ES(0.081)PNS(0.042)FLDQES(0.698)R 84.81700000000001 0.007137699999999999 3509900.0 3781.9 5058.0 6180.3 8066.2 7693.1 6670.6 6164.5 5589.0 5476.1 3866.0 True False 4422.1009740701775 5560.124812842532 6327.661790918272 7614.276964973234 6185.692280380432 6320.781993079835 5580.553932884899 5442.294672034997 5556.177602736629 4566.875196760837 0.9682990630457027 1.2174899845711091 1.3855561008994322 1.6672837852836087 1.3544693064456368 1.384049644615425 1.2219633102395786 1.1916889421228485 1.2166256714607566 1.0 12.156991649050033 -8.380719816547321 0.8939762850401343 1.0140912712783259 1.3369647497980472 0.24303493244562113 0.16700247713061658 0.8651146986030468 1.5200855676087608 0.17322611909474572 0.06181541381240622 4.161790202336156e-09 8.380719816547321 0.32287347851972137 GSET(ph)PGATPGSK ddPTM_PC-9_AZD4547_30min_R2 4 GSETPGATPGSK 12 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 GS(0.108)ET(0.872)PGAT(0.011)PGS(0.008)K;GS(0.002)ET(0.998)PGATPGSK;GS(0.005)ET(0.995)PGATPGSK;GS(0.087)ET(0.91)PGAT(0.001)PGS(0.002)K 161.25 0.00034886 153368900.0 246218.0 243679.0 289085.0 343676.0 341271.0 302022.0 286007.0 379283.0 277852.0 297815.0 True False 324510.2023474508 322443.4713474353 285251.5440152166 264446.8079412699 293891.4124162566 283136.5165954628 311461.06893102487 320673.5274062813 292538.6894738994 287388.5874978314 1.1291687160329549 1.121977299637441 0.9925639236365608 0.9201715706378403 1.022627290022344 0.9852044545700666 1.0837628301206468 1.1158185862502321 1.017920342700132 1.0 18.132643246436672 -5.2504450455452885 23.24397637665237 1.019349705375166 1.125573068621742 0.4227081877604537 0.05058461302462888 306.108841400855 647158.7170297438 0.014536214941398558 0.03754451373731174 5.617653581346881e-06 5.2504450455452885 0.10622336324657611 GSET(ph)PGATPGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GSETPGATPGSK 12 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 GSET(1)PGATPGSK;GS(0.005)ET(0.995)PGATPGSK;GS(0.325)ET(0.671)PGAT(0.004)PGSK;GSET(1)PGATPGSK;GSET(0.985)PGAT(0.014)PGSK 169.09 0.00028159 278144900.0 300275.0 309692.0 293960.0 320394.0 369789.0 288067.0 346319.0 282543.0 274420.0 232186.0 True False 351105.6267984133 340436.1750768743 300969.1212495076 302443.36291136366 297331.5000025473 272960.25940702925 313513.15718756756 275126.545629054 278432.87334836565 274279.48381663533 1.2801016755345023 1.2412017491781007 1.097308180187167 1.1026831416729543 1.0840457181307916 0.9951902184179112 1.1430426834154361 1.0030883163429933 1.015142909976114 1.0 18.065287186659596 -1.522878752139712 0.37502965109367725 1.0182999179459429 4.988814452572076 0.7960446867161364 0.0433003523832738 28.18043238643997 0.38707100561107227 0.03319526840313011 80.96391143534927 0.029999999526171203 1.522878752139712 3.9705145346261332 GSET(ph)PGATPGSK ddPTM_PC-9_Lapatinib_30min_R1 3 GSETPGATPGSK 12 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 GS(0.009)ET(0.991)PGATPGSK;GS(0.006)ET(0.99)PGAT(0.005)PGSK;GS(0.001)ET(0.994)PGAT(0.005)PGSK 165.35 0.0011183 151039600.0 134316.0 135516.0 155469.0 124187.0 148904.0 140723.0 144766.0 140945.0 156993.0 116320.0 True False 132400.6292094626 135202.2210280779 142686.9389476952 133320.12625568733 140145.75947652786 134704.6053313351 152261.27513452203 147493.8192450192 139310.79513042 136425.7570133429 0.9704958367686638 0.9910314883930216 1.0458944269133865 0.9772357447329258 1.0272675962708504 0.987383968249929 1.1160742550956149 1.0811288313437308 1.0211473125034223 1.0 17.057756523544953 -7.232821563255729 24.994843687983558 1.0613483519971252 1.0017889253497847 0.34467174879670426 0.03642216072715544 738.8650298989579 645326.112610355 0.013630631596082375 0.010557067053041602 5.850304037490385e-08 7.232821563255729 -0.059559426647340485 GSFS(ph)DTGLGDGK ddPTM_PC-9_AZD4547_30min_R2 2 GSFSDTGLGDGK 12 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 GSFS(0.5)DT(0.5)GLGDGK;GS(0.001)FS(0.935)DT(0.064)GLGDGK 152.0 0.00011493 139003000.0 452940.0 455770.0 623230.0 747430.0 575000.0 554850.0 538290.0 594620.0 480030.0 515100.0 True False 596965.498262735 603088.7394318788 614965.5629887527 575121.561178387 495171.1752224704 520155.14178766083 586196.7671940939 502735.14200827095 505403.40579933213 497066.50578423747 1.2009771153678594 1.21329587170708 1.2371897036564599 1.1570314122674583 0.9961869678610175 1.0464497924015133 1.1793125474612955 1.0114041806439762 1.0167722023473322 1.0 18.92307936675978 -6.05950624368493 4.424611951369038 1.0499454218490387 1.2150324799785857 0.7138800519869631 0.05059663264678892 0.12758033504589705 5.060398683930311 0.015812459420874128 0.021398439981823617 8.719543654440165e-07 6.05950624368493 0.16508705812954694 GSFS(ph)DTGLGDGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GSFSDTGLGDGK 12 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 GS(0.183)FS(0.739)DT(0.078)GLGDGK;GS(0.001)FS(0.996)DT(0.004)GLGDGK;GS(0.041)FS(0.48)DT(0.48)GLGDGK;GS(0.044)FS(0.478)DT(0.478)GLGDGK;GS(0.001)FS(0.897)DT(0.102)GLGDGK 148.89 0.00015469 101618900.0 390058.0 394207.0 401902.0 434374.0 479976.0 448589.0 474225.0 405218.0 389866.0 301177.0 True False 456087.11540333275 433341.265736698 411484.8679018234 410037.43303950893 385928.1483365457 425064.2031441983 429302.9749083202 394581.4568639604 395567.0526959905 355778.0059841794 1.2819429749224405 1.2180102717084982 1.1565775876548174 1.1525092224440157 1.0847442558146976 1.194745588526065 1.20665968015856 1.1090664690540386 1.1118367241441576 1.0 18.440617801123054 -4.369562812874316 0.021142469448921425 6.171831837571774e-10 2.4595160161668335 0.6581520387438585 0.0442044138656991 1106.117922491018 3.246620256055453 158.17209399664767 223.8373392755595 4.270091557912371e-05 4.369562812874316 2.4595160155496503 GSFS(ph)DTGLGDGK ddPTM_PC-9_Lapatinib_30min_R1 2 GSFSDTGLGDGK 12 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 GS(0.01)FS(0.977)DT(0.013)GLGDGK;GS(0.001)FS(0.762)DT(0.237)GLGDGK 161.87 0.00013868 179019000.0 620240.0 544790.0 565460.0 486720.0 513790.0 510320.0 480450.0 550580.0 526590.0 443400.0 True False 611395.2638619132 543528.5722267992 518970.0615387215 522515.01245032373 483569.882350005 488494.80321402324 505325.3501400954 576161.9567911096 467279.88896146807 520041.0992066368 1.1756672016781835 1.045164647671106 0.9979404749556348 1.0047571494781107 0.9298685874784292 0.9393388406402112 0.9717027190947188 1.107916196758467 0.8985441529031839 1.0 18.98826611938002 -4.486077791994558 1.2939361112448577 0.9796595327033946 1.3954981791473111 0.5574132580404125 0.053122338330382955 2.014154569449871 1.8031782783559613 0.015622062105636492 1.332519355056931 3.265293381212503e-05 4.486077791994558 0.41583864644391655 GSFSDT(ph)GLGDGK ddPTM_PC-9_AZD4547_30min_R2 1 GSFSDTGLGDGK 12 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 GSFS(0.312)DT(0.688)GLGDGK 106.54 0.0040555999999999995 86552000.0 93282.0 87111.0 113420.0 154140.0 118680.0 106090.0 105850.0 126590.0 95945.0 118070.0 True False 122943.73561386572 115267.92720154977 111915.97669268852 118605.4044392605 102203.33056591781 99456.17552897678 115270.44494137907 107028.42424880911 101016.45682440037 113936.40523771085 1.0790557711326987 1.0116865365469527 0.982267050282945 1.0409789934289089 0.8970208455557838 0.8729095438940409 1.011708634311263 0.9393698530817319 0.8866038612824849 1.0 16.79786926857757 -5.3221537135026304 0.8328152004981138 0.9361346112286756 1.0864961681659975 0.41301609972160624 0.05085404941295603 1.3248220623682234 1.19415682245746 0.021253351014154855 0.15880815051551558 4.762623894131338e-06 5.3221537135026304 0.1503615569373219 GSFSDT(ph)GLGDGK ddPTM_PC-9_Lapatinib_30min_R1 1 GSFSDTGLGDGK 12 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 GS(0.014)FS(0.433)DT(0.553)GLGDGK 147.73 0.00034161 71295000.0 355310.0 305050.0 345740.0 320250.0 335170.0 321980.0 289410.0 319370.0 325570.0 250090.0 True False 350243.21424412687 304343.6754672158 317314.5917949955 343802.25332268275 315455.959569574 308209.66597203945 304394.2337059942 334209.0961175053 288900.8781959124 293317.7232760216 1.1940745016438592 1.037590473797652 1.0818118600231736 1.1721155117488538 1.07547527659186 1.050770688281949 1.037762840602541 1.1394098262620276 0.9849417722503158 1.0 18.16210472081268 -1.5228806730830484 0.053974565489299714 0.8432016799244044 1.535506638694621 0.3437591385978438 0.054255667303732893 542.23070745384 2.208979964716566 6.294266751883388 30.48590410641003 0.029999866832402033 1.5228806730830484 0.6923049587702166 GSFSEQGINEFLR ddPTM_PC-9_Lapatinib_30min_R1 1 GSFSEQGINEFLR 13 0 Q15084-3;Q15084;Q15084-4;Q15084-5;Q15084-2 Q15084-3 PDIA6 Protein disulfide-isomerase A6 0 144.28 0.00041886 3593500.0 11162.0 10519.0 8584.3 7905.9 10101.0 9809.0 10314.0 8273.2 9076.8 8118.7 False True 11002.827833139889 10494.643901785437 7878.531990356261 8487.326259309275 9506.879039330077 9389.491935895807 10848.008453210417 8657.60307480149 8054.475201058623 9522.006477512243 1.1555156845487182 1.1021462678659413 0.8274025027143899 0.8913380052149164 0.9984113182218588 0.9860833384298372 1.1392565714830947 0.9092204563447649 0.8458800380025542 1.0 13.217049894975327 -5.076708074073177 7.2556661460954714 0.9543298300686027 1.1428203798264343 0.41688828352351714 0.08561499569298751 0.24027184245192498 19.69668717750622 0.023355630874045435 0.06339664396719735 8.380924454040817e-06 5.076708074073177 0.18849054975783153 GSFSGRLS(ph)PAYSLGSLTGASPCQSPCVQR ddPTM_PC-9_Lapatinib_30min_R1 1 GSFSGRLSPAYSLGSLTGASPCQSPCVQR 29 1 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 GS(0.045)FS(0.041)GRLS(0.674)PAY(0.156)S(0.031)LGS(0.04)LT(0.01)GAS(0.003)PCQSPCVQR 49.208 0.007735 4127600.0 9191.4 6709.4 9042.0 7321.8 7888.9 7540.0 4941.6 3858.0 7317.8 4331.6 True False 9060.328950503674 6693.8647965243035 8298.601663129353 7860.269596808796 7424.890412174145 7217.5317765984755 5197.451868565503 4037.2567643214393 6493.592304149782 5080.311288505803 1.783420037863163 1.3176091810887973 1.6334829091880507 1.5472023563974604 1.4615030439124763 1.420686915962833 1.023057756386844 0.7946868872889201 1.2781878777470832 1.0 12.31070118335727 -7.174289897626004 2.945545810973804 1.0008292979444193 1.536192970571957 0.717138126464152 0.1562162377648111 0.13981277373280676 2.356664059573606 0.0638289973986931 0.04636953582017045 6.694376013020979e-08 7.174289897626004 0.5353636726275377 GSFSGRLSPAY(ph)SLGSLTGASPCQSPCVQR ddPTM_PC-9_AZD4547_30min_R2 1 GSFSGRLSPAYSLGSLTGASPCQSPCVQR 29 1 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 GS(0.057)FS(0.106)GRLS(0.308)PAY(0.473)S(0.049)LGS(0.006)LT(0.001)GASPCQSPCVQR 57.073 0.0093289 4981200.0 5197.3 6987.0 6267.4 12251.0 8802.2 9755.0 7588.9 7920.8 5166.9 7574.5 True False 6849.933289444327 9245.411111768075 6184.290180953587 9426.721226063191 7580.166467031693 9145.018307900553 8264.297398352688 6696.822361876669 5440.011785564589 7309.31906049837 0.9371506747411406 1.2648799478097617 0.8460829428523982 1.2896852836822874 1.0370550805473877 1.2511450426788484 1.1306521619798062 0.9162033161294316 0.744256987626105 1.0 12.835521294971047 -7.83751078913625 4.650412328184959 0.8612615251183936 1.113887242847855 0.32346422739838054 0.14673695381764318 0.21903426762632439 8.684333986017988 0.07798523710053036 0.0364288336423577 1.4537482698299172e-08 7.83751078913625 0.2526257177294614 GSGDISSDSIDHS(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 2 GSGDISSDSIDHSPAK 16 0 Q5JSS2;H0Y306;Q9H5I1-3;Q9H5I1-2;Q9H5I1 Q5JSS2 SUV39H2 Histone-lysine N-methyltransferase SUV39H2 1 GSGDISSDS(0.001)IDHS(0.999)PAK;GSGDISSDSIDHS(1)PAK 98.943 0.0011229 13092500.0 41501.0 39486.0 77203.0 109129.0 98463.0 80314.0 59516.0 92978.0 74593.0 90180.0 True False 54697.45472557464 52249.07730918481 76179.23777645586 83970.99507624282 84793.11204509587 75291.95288372364 64812.808702230715 78610.38652188773 78535.83369537239 87022.82564865553 0.6285414696416456 0.6004065820631284 0.8753937511064122 0.9649306885904381 0.9743778303342864 0.8651977492400222 0.7447794095299185 0.9033306599267181 0.9024739556544811 1.0 16.409106241786645 -5.28376167142933 5.858671567031689 0.8989207145299979 0.6129780664201752 0.7445900008515381 0.06778513543983325 0.08201904419240243 10.311116847452912 0.019096159280904985 0.04317102552770053 5.2028143399269005e-06 5.28376167142933 -0.28594264810982273 GSGDISSDSIDHS(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 2 GSGDISSDSIDHSPAK 16 0 Q5JSS2;H0Y306;Q9H5I1-3;Q9H5I1-2;Q9H5I1 Q5JSS2 SUV39H2 Histone-lysine N-methyltransferase SUV39H2 1 GSGDISSDSIDHS(1)PAK;GSGDISSDS(0.007)IDHS(0.992)PAK 92.096 0.0017614 14901800.0 70922.0 57774.0 76010.0 51255.0 76474.0 79361.0 56832.0 61985.0 80642.0 64818.0 True False 69910.63927449821 57640.22785262397 69760.75120708499 55024.46368166772 71975.94967366877 75966.91502952666 59774.4828788883 64865.04938736769 71559.24876209335 76021.70493544401 0.9196141987852656 0.7582075132565207 0.9176425504574557 0.7237993902977223 0.9467815768508374 0.9992792860149101 0.7862817984633139 0.8532438129669637 0.9413002355427298 1.0 16.214123760370587 -6.311179068673592 24.999693624688643 0.9109732542941577 0.8309739025737733 0.21950481787766274 0.083039891400008 652.4173348369916 327910.0541671847 0.02548914155396318 0.028902005688427126 4.884509193143693e-07 6.311179068673592 -0.0799993517203843 GSGFTVTGGTEELPEEEGGGGS(ph)GGRR ddPTM_PC-9_Lapatinib_30min_R1 1 GSGFTVTGGTEELPEEEGGGGSGGRR 26 1 Q7Z3Z5;Q93074-3;Q93074;Q93074-2 Q7Z3Z5 TNRC11;MED12 Mediator of RNA polymerase II transcription subunit 12 1 GSGFTVTGGTEELPEEEGGGGS(1)GGRR 73.459 5.3e-05 1428100.0 2508.2 2756.1 3330.3 2793.5 2922.0 3917.0 2290.1 1939.0 3030.4 2941.1 True False 2472.432608052453 2749.718419784278 3056.495589329759 2998.943308842822 2750.1337048730306 3749.4790409729744 2408.6701724546406 2029.0930186675148 2689.0844404732998 3449.4652162305874 0.7167582373114086 0.797143396850669 0.8860781013092089 0.8693936946318668 0.7972637880019694 1.0869740107338226 0.6982735066065463 0.5882340860027027 0.7795656056540278 1.0 11.752156997365763 -10.857856751661283 6.330316988466038 1.0000120066011586 0.8053651136895134 0.18265473409190003 0.1253723786152579 2.2637423032369158e-05 2.3781382606272385e-06 0.12934946001962314 0.031369918003969655 1.3872133139244444e-11 10.857856751661283 -0.19464689291164528 GSGGFGS(ph)TGKN ddPTM_PC-9_AZD4547_30min_R2 1 GSGGFGSTGKN 11 1 P33316-2;A0A0C4DGL3;H0YNW5;P33316 P33316-2;H0YNW5;P33316 DUT Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial 1 GSGGFGS(0.802)T(0.198)GKN 80.69 0.023339 18614000.0 33925.0 28635.0 33622.0 48857.0 43466.0 39803.0 33121.0 48409.0 31206.0 43769.0 True False 44712.44431616392 37890.703762055055 33176.15031177548 37593.77348312542 37431.49617777371 37314.11211782324 36068.70483612109 40928.50137815471 32855.48545168836 42236.660632246734 1.0586169372023455 0.897104628890248 0.7854823230614553 0.890074473700779 0.8862323776893387 0.8834531792822362 0.8539667742715307 0.9690278721255422 0.7778902252183246 1.0 15.3662081545928 -4.391856482013217 0.0013885334069024622 1.7804445461786547 3.684643900250448e-08 0.0 0.08413694292650721 9446544.850468988 1836.2541222933028 1163995.6430838194 1190649.054863321 4.056425629071757e-05 4.391856482013217 -1.7804445093322157 GSGGFGS(ph)TGKN ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSGGFGSTGKN 11 1 P33316-2;A0A0C4DGL3;H0YNW5;P33316 P33316-2;H0YNW5;P33316 DUT Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial 1 GSGGFGS(0.944)T(0.056)GKN 103.43 0.0042723 12353000.0 78407.0 71727.0 84627.0 87202.0 75842.0 79150.0 86915.0 57407.0 62726.0 57363.0 True False 91679.75649116072 78847.58253277124 86644.82862968458 82316.35465269833 60981.304536352414 74999.23466438832 78681.7819898921 55900.12707774432 63643.2490840667 67762.45781474184 1.3529579570712624 1.1635879965914964 1.2786553413774617 1.214778172269753 0.899927577938087 1.106796256851122 1.16114120602005 0.8249424368663197 0.9392110489566836 1.0 16.048198583216497 -5.999605032984455 0.543364086002793 0.9430431495775844 1.353314179976196 0.5739306456345619 0.1068799835416042 1.0624155068851193 0.5626559622879853 0.08152177925771006 0.2392718551060576 1.0009098588328638e-06 5.999605032984455 0.4102710303986117 GSGGFGS(ph)TGKN ddPTM_PC-9_Lapatinib_30min_R1 1 GSGGFGSTGKN 11 1 P33316-2;A0A0C4DGL3;H0YNW5;P33316 P33316-2;H0YNW5;P33316 DUT Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial 1 GSGGFGS(0.911)T(0.089)GKN 78.548 0.026836000000000002 18048000.0 40888.0 45820.0 49788.0 45374.0 43573.0 47251.0 44404.0 40271.0 46782.0 36531.0 True False 40304.92962205915 45713.906605172386 45694.62282723783 48710.95532322683 41010.121807814015 45230.184877460815 46703.02184955937 42142.13767651338 41512.918523700435 42845.33467550225 0.9407075455779872 1.066951791867092 1.0665017130409935 1.1369022016550703 0.9571665647709934 1.0556618408986815 1.0900375082438751 0.9835875479952562 0.9689017214617849 1.0 15.386850500878 -7.797604506645338 20.031040559156594 0.9821819823848872 1.0471141556702641 0.20045264773605054 0.055367444779677054 34.594161196959476 19157.658646096774 0.030171282323770143 0.014497592647913773 1.593659343644539e-08 7.797604506645338 0.06493217328537693 GSGGGGGGGGQGS(ph)TNYGK ddPTM_PC-9_AZD4547_30min_R2 1 GSGGGGGGGGQGSTNYGK 18 0 Q99729-3;Q99729-4 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 1 GSGGGGGGGGQGS(0.774)T(0.224)NY(0.002)GK 171.85 6.2387e-25 0.0 4678.9 5569.1 5758.4 8916.3 10419.0 6806.0 5684.0 10428.0 8023.8 8153.8 True False 6166.692872834175 7369.202665313813 5682.039853528281 6860.784790461781 8972.501695031158 6380.419744087259 6189.8649886329595 8816.592211601092 8447.921687087637 7868.337943823565 0.7837351314676138 0.9365640771820737 0.7221397827718534 0.8719484139401147 1.1403299857086504 0.8108980307709988 0.7866801137452208 1.1205151932400006 1.0736602504114645 1.0 12.941843207124503 -7.027647516707003 0.47375065783264436 1.0544735378158372 0.8172875566536987 0.2555276576300124 0.12459569427675243 1.6497676708192268 0.8010541881085679 0.1284622613719084 0.1458544704501724 9.383232624889861e-08 7.027647516707003 -0.23718598116213852 GSGGGGGGGGQGS(ph)TNYGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSGGGGGGGGQGSTNYGK 18 0 Q99729-3;Q99729-4 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 1 GSGGGGGGGGQGS(0.817)T(0.183)NYGK 142.98 1.2085999999999998e-08 0.0 5261.4 4243.0 5783.7 4774.1 5194.8 5781.3 5137.2 6698.9 3706.5 3052.0 True False 6152.051102613186 4664.2169989898875 5921.605342804392 4506.622654841031 4176.916231183824 5478.118450603008 4650.56722589282 6523.060973071252 3760.700550490915 3605.3034403812935 1.7063892691269702 1.2937099681397703 1.642470721459753 1.2499981567056158 1.1585477617224023 1.5194611330755692 1.2899239419916844 1.8092959666056234 1.0431023664663261 1.0 11.815904973673328 -12.972517831818491 0.2309446120949769 1.3372445068911962e-11 1.469562391926169 0.252977392560073 0.2315639667096317 108.49301148973132 2.06075360259127 51.94317524651094 0.396620529715702 1.0653251212877058e-13 12.972517831818491 1.4695623919127967 GSGGGGGGGGQGST(ph)NYGK ddPTM_PC-9_Lapatinib_30min_R1 2 GSGGGGGGGGQGSTNYGK 18 0 Q99729-3;Q99729-4 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 1 GSGGGGGGGGQGS(0.385)T(0.611)NY(0.003)GK;GSGGGGGGGGQGS(0.318)T(0.682)NYGK 175.16 8.1374e-33 0.0 11824.099999999999 11089.8 9364.2 9322.6 10011.5 8654.1 7068.4 8510.8 10709.1 8608.7 True False 11655.486165725626 11064.12224945528 8594.311622857318 10008.215103281926 9422.643253366308 8283.984316692424 7434.367166053177 8906.242838202928 9502.928386177604 10096.702324628295 1.1543854410063255 1.0958154349531741 0.8511998617502783 0.9912360275165756 0.9332396806809097 0.8204643506707914 0.7363163661781887 0.8820942275854218 0.9411912999552009 1.0 13.301596552056353 -5.175275539713237 4.238416707549688 0.8866787347701912 1.140639092662513 0.595461291159336 0.07619741273752265 0.15501932319710457 4.999117431161747 0.021089168173932547 0.06195862991052293 6.679200188261317e-06 5.175275539713237 0.25396035789232174 GSGGGGGGGGQGSTNYGK ddPTM_PC-9_Lapatinib_30min_R1 3 GSGGGGGGGGQGSTNYGK 18 0 Q99729-3;Q99729-4 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 0 ;; 185.86 3.1188999999999996e-42 0.0 3730.11 2240.71 4109.05 3695.8999999999996 3687.34 3244.09 2007.02 4340.62 4823.24 2285.74 False True 3676.917947381603 2235.5217736638133 3771.2197703916936 3967.7088151609705 3470.4579107893674 3105.3478330431494 2110.9336751757187 4542.30105141237 4279.995920231137 2680.8271134428983 1.3715610115041914 0.8338925559406202 1.406737402602751 1.4800315899764875 1.2945474526823821 1.1583543815531816 0.7874188024250157 1.6943655294424569 1.5965206778047236 1.0 11.388462467570392 -7.79194317594221 24.99912625389245 1.4840820588634198 1.1988914887689228 0.12864784418858966 0.2750599165612627 371.2590522480417 304257.16377597535 0.14999169400000287 0.07206649879264407 1.614569796916744e-08 7.79194317594221 -0.285190570094497 GSGGGGGPQVPHQS(ph)PPKR ddPTM_PC-9_AZD4547_30min_R2 2 GSGGGGGPQVPHQSPPKR 18 1 Q9NYF3;D6RHW3 Q9NYF3 FAM53C Protein FAM53C 1 GSGGGGGPQVPHQS(1)PPKR;GSGGGGGPQVPHQS(1)PPKR 54.81100000000001 0.015186000000000002 15391400.0 48258.0 38776.0 55614.0 64183.0 61467.0 49806.0 50667.0 51357.0 46641.0 61199.0 True False 63603.040171243585 51309.58369399151 54876.5220224579 49386.600967465034 52933.36804765141 46691.62294651923 55176.26484501515 43420.95571645545 49106.34804051131 59056.441637525815 1.0769873430848356 0.8688228120637094 0.9292216141175039 0.8362610343269252 0.8963182775647685 0.7906270959076935 0.9342971454947073 0.7352450386862588 0.8315155244522557 1.0 15.849806811088165 -1.9299492641332856 1.1428174833041753 0.8548046530600718 199.9999999971007 0.4043005588321792 0.07370155377410384 1384.6625017408537 2.678516597760607 0.02118431108118597 721785.146587469 0.011750348187783914 1.9299492641332856 199.14519534404062 GSGGGGGPQVPHQS(ph)PPKR ddPTM_PC-9_Lapatinib_30min_R1 1 GSGGGGGPQVPHQSPPKR 18 1 Q9NYF3;D6RHW3 Q9NYF3 FAM53C Protein FAM53C 1 GSGGGGGPQVPHQS(1)PPKR 67.579 0.0047075 11469000.0 30055.0 23401.0 24000.0 23870.0 29440.0 29126.0 20664.0 21428.0 24880.0 24549.0 True False 29626.410188588034 23346.81642225314 22026.81264267911 25625.479427985716 27708.39708126697 27880.34887602215 21733.880810271465 22423.623106759936 22077.75240198511 28792.261940513665 1.0289712649113072 0.8108712149982832 0.765025432464725 0.8900127222004757 0.9623556891262653 0.9683278421689976 0.7548514547128952 0.7788072765206265 0.7667946494651554 1.0 14.81339351204841 -7.26973229458931 24.962237261927857 0.806680621100677 0.8956798895401972 0.12316497501168311 0.09706269049953907 1207.6388527168851 3635058.6707392475 0.04085864317365784 0.028053389411149182 5.373629325981347e-08 7.26973229458931 0.08899926843952022 GSGIFDEST(ph)PVQTR ddPTM_PC-9_AZD4547_30min_R2 1 GSGIFDESTPVQTR 14 0 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2;H3BMV3;H3BMT0;H3BTV5 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 GSGIFDES(0.038)T(0.961)PVQTR 141.06 0.00031365 13503000.0 39659.0 49877.0 57228.0 92642.0 65098.0 60473.0 56163.0 86382.0 57110.0 59408.0 True False 52269.73704155481 65998.76485210468 56469.11932788905 71284.81820463203 56060.26637327362 56691.61375024813 61161.39819785239 73033.64676088667 60128.718007624186 57328.14400238786 0.9117639852317152 1.1512454484721442 0.9850156552344861 1.2434523992554658 0.9778838535386488 0.9888967231851563 1.0668651368742177 1.2739579840199367 1.0488516426612324 1.0 15.806955952116505 -7.545569622400815 24.988383613733586 1.130925189795288 1.049505507673742 0.049416241029688335 0.11146166119602244 562.4832348200599 619428.6784211328 0.05002698183371591 0.028885266408191862 2.847281311640132e-08 7.545569622400815 -0.08141968212154604 GSGIFDEST(ph)PVQTR ddPTM_PC-9_Lapatinib_30min_R1 1 GSGIFDESTPVQTR 14 0 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2;H3BMV3;H3BMT0;H3BTV5 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 GSGIFDES(0.058)T(0.942)PVQTR 142.57 0.00037178 14569000.0 59174.0 47774.0 69883.0 51053.0 42858.0 48768.0 36205.0 30948.0 44930.0 29164.0 True False 58330.167908817406 47663.38223822584 64137.489496181006 54807.607927815436 40337.17670206995 46682.3063237605 38079.51774757446 32385.95706122859 39869.51026612502 34204.958541412685 1.7053132176200654 1.3934641137049983 1.875093326557562 1.6023293190505896 1.1792786315829868 1.3647818420022706 1.1132747815341089 0.9468205325265402 1.1656061567171363 1.0 15.061917860934413 -6.58117591319791 1.1314922335969608 1.0547770558463527 1.6553059209756364 0.7365469806553904 0.1513613718148401 0.25376111006736846 0.6896018395105935 0.07413814655481006 0.07993203466325013 2.623155805509349e-07 6.58117591319791 0.6005288651292837 GSGNLEAIHIIK ddPTM_PC-9_Lapatinib_30min_R1 1 GSGNLEAIHIIK 12 0 P78371;P78371-2;F5GWF6;F8VQ14 P78371 CCT2 T-complex protein 1 subunit beta 0 75.08800000000001 0.016891999999999997 5509400.0 41309.0 46976.0 57359.0 49177.0 46532.0 45522.0 48238.0 49142.0 46052.0 42923.0 False True 40719.926084857165 46867.229958196855 52643.16443214299 52793.64062966292 43795.07924543187 43575.13017696494 50735.527609653276 51425.31672169109 40865.13881094125 50342.18335869762 0.8088629329943827 0.9309733275622739 1.0457068192106498 1.0486958869761012 0.869947950675552 0.8655788698412992 1.0078134126236242 1.021515422866663 0.8117474468631878 1.0 15.619480167610876 -4.42735184578404 0.005559363518951365 1.8619835152170143 1.3380863424076277e-05 0.02449400087725928 0.08943431885064335 152170.01592523206 119.26399205180681 19089.263765416017 20885.63662159506 3.7380762350253445e-05 4.42735184578404 -1.8619701343535902 GSGPQRPHS(ph)FSEALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSGPQRPHSFSEALR 15 1 Q6DT37 Q6DT37 CDC42BPG Serine/threonine-protein kinase MRCK gamma 1 GSGPQRPHS(0.96)FS(0.04)EALR;GS(0.001)GPQRPHS(0.924)FS(0.076)EALR 71.402 0.010263 10421400.0 28932.0 32228.0 42394.0 43852.0 51454.0 41820.0 45554.0 35310.0 38906.0 35069.0 True False 33829.616166952685 35427.382852568015 43404.8337401403 41395.114610102195 41371.95806562956 39626.88558009755 41238.79533760056 34383.14991403751 39474.926647079345 41426.73209394873 0.8166131977350497 0.855181692155316 1.047749401080094 0.999236785470434 0.9986778095796947 0.956553500049933 0.9954633941214102 0.8299749503789585 0.952885362947697 1.0 15.33827439880931 -5.096539414914396 6.1145974866188535 0.9683782364490006 0.8256286910148715 0.5064565877589338 0.05438494409735304 0.18230206862134105 9.334772666843719 0.014839323235284257 0.041046808982603426 8.006829582709562e-06 5.096539414914396 -0.1427495454341291 GSGPQRPHS(ph)FSEALR ddPTM_PC-9_Lapatinib_30min_R1 2 GSGPQRPHSFSEALR 15 1 Q6DT37 Q6DT37 CDC42BPG Serine/threonine-protein kinase MRCK gamma 1 GS(0.002)GPQRPHS(0.934)FS(0.064)EALR;GSGPQRPHS(0.815)FS(0.185)EALR 70.335 0.011289 29774000.0 57631.0 48990.0 67076.0 46581.0 67831.0 62908.0 52631.0 64859.0 75852.0 49314.0 True False 56809.171371768934 48876.56666493662 61561.27020084762 50006.72212966075 63841.313940877066 60217.57148571041 55355.97565453921 67872.58591942048 67308.74900302956 57837.85919322543 0.9822142825511602 0.8450618219054268 1.0643767086050502 0.8646018858097373 1.1037980110500845 1.0411445431362667 0.9570889453153044 1.1734975475608618 1.163748968961034 1.0 15.81972653300591 -6.514838998816468 0.7511178303247118 1.0995843436135475 0.9263809907195952 0.2976395850127097 0.08955949934141243 0.8224546301027159 1.032608758492629 0.056652159340471964 0.07335519090779376 3.056053840235738e-07 6.514838998816468 -0.17320335289395228 GSGPQRPHSFS(ph)EALR ddPTM_PC-9_AZD4547_30min_R2 1 GSGPQRPHSFSEALR 15 1 Q6DT37 Q6DT37 CDC42BPG Serine/threonine-protein kinase MRCK gamma 1 GS(0.001)GPQRPHS(0.392)FS(0.608)EALR 73.168 0.008564200000000001 15064000.0 8661.3 15954.0 27985.0 42912.0 35738.0 42255.0 26447.0 27015.0 28004.0 28733.0 True False 11415.413233768337 21110.818502525817 27613.900614925817 33019.30138379103 30776.395582783687 39612.78817020381 28800.73176537224 22840.45249294241 29484.23426870091 27727.066415644556 0.41170649150706295 0.7613794472903334 0.9959185800970676 1.1908689108617858 1.1099766243362332 1.4286685643690356 1.0387226450008387 0.8237601537267227 1.0633737383795099 1.0 14.75900736370595 -4.930964248221191 1.6793291717474697 1.098437648919194 0.2875454245257761 0.6836123005681392 0.14546697554167823 0.43815657648793593 1.5420094674786426 0.04494990561346005 0.5286726815339912 1.1722918664160714e-05 4.930964248221191 -0.810892224393418 GSGS(ph)PTHSLSQK ddPTM_PC-9_AZD4547_30min_R2 4 GSGSPTHSLSQK 12 0 I3L419;I3L156;Q9BSJ6-2;Q9BSJ6;I3L2R2 I3L419 FAM64A Protein FAM64A 1 GS(0.001)GS(0.923)PT(0.076)HSLSQK;GS(0.002)GS(0.974)PT(0.024)HSLSQK;GSGS(0.987)PT(0.012)HS(0.001)LSQK;GSGS(0.846)PT(0.103)HS(0.051)LSQK 168.76 0.00022374 125590000.0 81586.0 78486.0 162552.0 240497.0 202940.0 169571.0 124861.0 218507.0 135479.0 177115.0 True False 107528.65090577907 103855.06462261769 160396.45427040994 185054.13229161038 174765.28399938758 158967.6985637117 135973.38711219208 184741.76394134265 142640.14335413958 170914.2577596104 0.6291379801503588 0.6076442421128438 0.9384615208405044 1.0827308073495403 1.0225319191637812 0.9301020327239086 0.795564915967617 1.0809031754459042 0.8345713530509659 1.0 17.382913226869803 -5.278161731196301 6.014873680057804 0.9640248798809599 0.6164006523174289 0.7026161587180277 0.08909546456444631 0.07893719102717138 11.810001693416304 0.023464511387303166 0.053528656850255256 5.270335576599168e-06 5.278161731196301 -0.34762422756353095 GSGS(ph)PTHSLSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GSGSPTHSLSQK 12 0 I3L419;I3L156;Q9BSJ6-2;Q9BSJ6;I3L2R2 I3L419 FAM64A Protein FAM64A 1 GS(0.001)GS(0.983)PT(0.016)HS(0.001)LSQK;GSGS(0.998)PT(0.001)HSLSQK;GS(0.032)GS(0.867)PT(0.095)HS(0.005)LSQK 147.7 0.00013924 62468000.0 67149.0 83473.0 123283.0 133738.0 145508.0 125348.0 127926.0 110264.0 118349.0 79538.0 True False 78515.99944679628 91759.64778616137 126222.53427338091 126245.09344444625 116996.75193791771 118774.53021745742 115807.92317596459 107369.6868343649 120079.63023068891 93957.6097775385 0.8356534359771072 0.9766068762649327 1.343398736645551 1.3436388361023035 1.2452078359052399 1.264128903435043 1.2325550155028488 1.1427460435464663 1.2780192100990966 1.0 16.519722392112484 -5.085914054635434 4.161047178304267 1.2411623050142384 0.8605258962556402 0.655421968153528 0.09627675578648971 0.1171861410853613 3.591577339068134 0.02422013172452799 0.07713008593927244 8.20513905106517e-06 5.085914054635434 -0.38063640875859817 GSGS(ph)PTHSLSQK ddPTM_PC-9_Lapatinib_30min_R1 4 GSGSPTHSLSQK 12 0 I3L419;I3L156;Q9BSJ6-2;Q9BSJ6;I3L2R2 I3L419 FAM64A Protein FAM64A 1 GS(0.001)GS(0.871)PT(0.126)HS(0.002)LSQK;GS(0.003)GS(0.825)PT(0.169)HS(0.002)LSQK;GS(0.001)GS(0.966)PT(0.03)HS(0.003)LSQK;GS(0.023)GS(0.97)PT(0.006)HSLSQK 137.62 6.697e-05 111915000.0 100454.0 74414.0 124815.0 79144.0 104748.0 94253.0 75436.0 85442.0 109385.0 66997.0 True False 99021.50753899271 74241.69895498271 114553.19249983318 84964.51377664434 98586.92858249144 90222.01890447429 79341.70696881726 89411.94724135644 97064.90942488515 78577.34218210884 1.2601788860394767 0.9448232390314506 1.4578399996572502 1.0812851569824384 1.2546482973935271 1.148193822786447 1.0097275469681444 1.1378845957163783 1.2352786023219007 1.0 16.261825750126164 -6.999637311780934 24.871393531210508 1.103177013281677 1.194155870509751 0.11063816215778566 0.1380173888594293 30.54469979099804 2094419.20383626 0.04697290479336195 0.041047117415667196 1.0008354692968316e-07 6.999637311780934 0.09097885722807408 GSGS(ph)QSSVPSVDQFTGVGIR ddPTM_PC-9_AZD4547_30min_R2 4 GSGSQSSVPSVDQFTGVGIR 20 0 Q9UQE7 Q9UQE7 SMC3 Structural maintenance of chromosomes protein 3 1 GS(0.109)GS(0.833)QS(0.044)S(0.014)VPSVDQFTGVGIR;GS(0.002)GS(0.998)QS(0.001)SVPSVDQFTGVGIR;GS(0.262)GS(0.728)QS(0.009)S(0.001)VPSVDQFTGVGIR;GSGS(1)QSSVPSVDQFTGVGIR 206.8 3.6594999999999995e-21 22741800.0 44386.0 43504.0 61791.0 50417.3 50079.1 51861.0 51752.2 62101.0 49069.7 48479.0 True False 58499.82471384679 57565.81723291231 60971.610966477805 38794.37042452013 43126.48139318885 48618.1234716587 56358.04554270419 52504.71738901415 51663.424164222015 46781.764965859205 1.250483489807178 1.2305182858090793 1.3033200224697419 0.829262650796348 0.9218652059122194 1.0392537243333946 1.2047011390834366 1.1223329736988652 1.104349615751466 1.0 15.513658671754085 -5.727076446221456 24.99999971709895 1.039726849177838 1.2583485610772025 0.5225733666706951 0.10041930412430335 173.7589299339626 126413.28592718202 0.03078314593346677 0.0533146297805127 1.8746644932116018e-06 5.727076446221456 0.21862171189936452 GSGS(ph)QSSVPSVDQFTGVGIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GSGSQSSVPSVDQFTGVGIR 20 0 Q9UQE7 Q9UQE7 SMC3 Structural maintenance of chromosomes protein 3 1 GSGS(0.94)QS(0.03)S(0.03)VPSVDQFTGVGIR;GS(0.025)GS(0.96)QS(0.013)S(0.001)VPS(0.001)VDQFTGVGIR;GS(0.083)GS(0.903)QS(0.011)S(0.002)VPSVDQFTGVGIR;GS(0.042)GS(0.953)QS(0.004)SVPSVDQFTGVGIR 171.3 1.4461999999999999e-08 17903800.0 37840.0 44954.7 45656.0 44986.7 47326.9 36000.1 49812.0 33373.0 33372.7 24621.9 True False 44245.56462593286 49417.505520737854 46744.61219134422 42466.24104784925 38053.5336839943 34112.191381445926 45093.44675235013 32496.99411161635 33860.712602554486 29085.655563146836 1.5212160004395596 1.699033580778307 1.607136276844737 1.460040704795266 1.3083264910903458 1.1728183780278274 1.5503672129531116 1.1172859432741091 1.1641722335960656 1.0 14.828020201062479 -6.406081909196811 0.26460924196194513 0.9700169360998182 1.861202562252954 0.6970189302779414 0.12464992548510324 2.2067478085803343 0.2757621029891643 0.20784939513950745 0.6408535497466533 3.925708884108161e-07 6.406081909196811 0.8911856261531358 GSGS(ph)QSSVPSVDQFTGVGIR ddPTM_PC-9_Lapatinib_30min_R1 4 GSGSQSSVPSVDQFTGVGIR 20 0 Q9UQE7 Q9UQE7 SMC3 Structural maintenance of chromosomes protein 3 1 GS(0.01)GS(0.99)QSSVPSVDQFTGVGIR;GS(0.207)GS(0.446)QS(0.037)S(0.307)VPS(0.003)VDQFTGVGIR;GS(0.068)GS(0.917)QS(0.015)SVPSVDQFTGVGIR;GS(0.012)GS(0.987)QSS(0.001)VPSVDQFTGVGIR 169.62 2.4043000000000002e-08 20486300.0 38151.7 44660.8 57268.0 46005.9 51634.9 46026.2 49233.0 46897.7 54436.0 37617.2 True False 37607.64976183508 44557.39066155137 52559.646100872786 49389.327357183414 48597.83670011925 44057.76671831256 51782.04384108091 49076.73835047115 48304.84444350728 44119.2828982317 0.852408454792505 1.0099300744377517 1.1913078057526492 1.11944991198311 1.101510122279595 0.9986056849550108 1.1736828080484583 1.1123648238724693 1.094869210701594 1.0 15.429121721531043 -4.883297724460134 3.3540629972200695 1.103060619016545 0.8440535062568036 0.6149919934854046 0.05953419490775272 0.1683019037001248 3.2271912881671523 0.014865220687207125 0.0971025880090209 1.3082847393476226e-05 4.883297724460134 -0.2590071127597414 GSGS(ph)RGRFDDRGR ddPTM_PC-9_AZD4547_30min_R2 1 GSGSRGRFDDRGR 13 3 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDH3;O15523-2;O15523;A0A2R8YF89;A0A2R8YCU0;A0A2R8Y650;C9J081;C9J8G5;O15523-3 A0A2R8Y5G6 DDX3X;DDX3Y ATP-dependent RNA helicase DDX3X;ATP-dependent RNA helicase DDX3Y 1 GS(0.01)GS(0.99)RGRFDDRGR 70.197 0.02374 6911600.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GSGS(ph)RGRFDDRGR ddPTM_PC-9_Lapatinib_30min_R1 1 GSGSRGRFDDRGR 13 3 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDH3;O15523-2;O15523;A0A2R8YF89;A0A2R8YCU0;A0A2R8Y650;C9J081;C9J8G5;O15523-3 A0A2R8Y5G6 DDX3X;DDX3Y ATP-dependent RNA helicase DDX3X;ATP-dependent RNA helicase DDX3Y 1 GS(0.01)GS(0.99)RGRFDDRGR 71.531 0.021197999999999998 4585900.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GSGT(ph)ASDDEFENLR ddPTM_PC-9_AZD4547_30min_R2 1 GSGTASDDEFENLR 14 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 GS(0.001)GT(0.499)AS(0.499)DDEFENLR 208.79 1.2991999999999998e-10 545400000.0 30590.0 29497.0 32462.0 58238.0 54920.0 38793.0 32513.0 46205.0 31800.0 35308.0 True False 40316.98368847324 39031.32840472632 32031.532669706005 44812.12886813063 47295.30598820532 36367.26757748707 35406.59401397314 39065.078935273144 33480.88307901331 34071.87766691877 1.183292100382774 1.1455584804069312 0.9401164497842223 1.3152233436092615 1.3881038917360724 1.0673690464907062 1.03917354834689 1.146549048959588 0.9826544755272094 1.0 15.056293834647589 -6.961488483516907 24.998883880288012 1.054158255542093 1.1886627510676868 0.2838600342455603 0.11673172039939271 257.67526504676937 167263.4680690106 0.0442095982390387 0.038989135408976965 1.0927266033816203e-07 6.961488483516907 0.13450449552559385 GSGTAEVELK ddPTM_PC-9_Lapatinib_30min_R1 1 GSGTAEVELK 10 0 P14618;P14618-2;H3BTN5;P14618-3;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 125.57 0.0017282 19310000.0 51548.0 64166.0 56574.0 47583.0 49326.0 37117.0 59006.0 44508.0 46170.0 48647.0 False True 50812.91606725458 64017.42756934726 51922.70410195536 51082.412552234804 46424.74165864721 35529.592433952996 62061.04196142463 46576.00416444238 40969.84840834617 57055.56913194706 0.8905864377541186 1.1220189114457901 0.9100374405499067 0.8953098414302257 0.8136759016685132 0.6227190960410375 1.0877297852888275 0.8163270452482988 0.7180692267497859 1.0 15.800080092827772 -5.655519723038495 2.492273898810822 0.8386548109406469 1.0068498388229885 0.1672671191604439 0.1346291342187733 0.45209697417832334 5.665695138518406 0.03860631638029462 0.0776210352497563 2.2104478687969386e-06 5.655519723038495 0.16819502788234164 GSGTAEVELKK ddPTM_PC-9_AZD4547_30min_R2 2 GSGTAEVELKK 11 1 P14618;P14618-2;H3BTN5;P14618-3;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ; 91.93700000000001 0.0050115 42385000.0 98513.0 73543.0 109061.0 154826.0 138704.0 136605.0 103718.0 122180.0 127908.0 123233.0 False True 129838.08480230696 97314.3365382509 107614.7798808085 119133.25773785476 119447.34380531713 128063.06775507497 112948.7010716104 103299.8884170909 134668.95575064243 118918.65017920594 1.0918227259277316 0.8183269520096456 0.9049445122244246 1.0018046585487257 1.0044458428119933 1.0768964124810425 0.9497980417823524 0.8686601156456271 1.1324460507052625 1.0 16.859615467157454 -5.771154885683805 24.47190303616428 1.0000814225144572 0.9263609543657667 0.09507627728018808 0.0909673297896332 325.5614701570042 820041.8261413062 0.025112202361834642 0.037807527685220485 1.6937336438453765e-06 5.771154885683805 -0.07372046814869049 GSGTAEVELKK ddPTM_PC-9_Lapatinib_30min_R1 2 GSGTAEVELKK 11 1 P14618;P14618-2;H3BTN5;P14618-3;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ; 109.16 0.0013262 85045000.0 254164.0 283731.0 254410.0 260770.0 274950.0 284628.0 260090.0 253276.0 238798.0 278440.0 False True 250539.5747520306 283074.03830188006 233493.39185099993 279947.8957032191 258777.9815724982 272455.12394027424 273556.1875698564 265044.1275894958 211902.05458558036 326567.98300202127 0.7671896444008717 0.8668150371009518 0.7149916832157877 0.8572423209702293 0.7924168780835337 0.8342983333384152 0.8376699548288641 0.8116047542476181 0.6488757796696464 1.0 18.31702382924204 -11.344799367536325 2.730384483806067 1.0661275220787765 0.797304474077437 0.48263465816909246 0.06431480876525321 22925683.127278414 17802672.367847174 10015840.276677486 0.015886812963622314 4.520647379905464e-12 11.344799367536325 -0.2688230480013395 GSGTAS(ph)DDEFENLR ddPTM_PC-9_AZD4547_30min_R2 4 GSGTASDDEFENLR 14 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 GSGT(0.061)AS(0.939)DDEFENLR;GSGT(0.001)AS(0.999)DDEFENLR;GSGT(0.002)AS(0.998)DDEFENLR;GSGT(0.002)AS(0.998)DDEFENLR 199.37 2.7239e-36 524113000.0 87653.0 99017.0 137813.0 182731.0 145058.0 121860.0 109058.0 142831.0 109265.0 124343.0 True False 115524.83070433943 131022.30886703011 135985.5095745853 140605.1911158072 124919.2005833412 114240.07493600856 118763.95072665958 120759.7508798613 115040.52483108129 119989.78941706389 0.9627888444973844 1.091945485558101 1.1333090110019532 1.1718096331270964 1.041081921972073 0.9520816353709038 0.9897838083026922 1.0064168915250042 0.9587526187850884 1.0 16.872552118736365 -6.530397614646227 7.075467140126122 0.9835413910264746 1.0949336583473606 0.489480179470432 0.05224931507849307 0.12039512962069082 34.14761635314421 0.017812891643873098 0.01841457649182899 2.948508508474022e-07 6.530397614646227 0.11139226732088592 GSGTAS(ph)DDEFENLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GSGTASDDEFENLR 14 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 GS(0.009)GT(0.009)AS(0.982)DDEFENLR;GSGT(0.012)AS(0.988)DDEFENLR;GS(0.001)GT(0.027)AS(0.972)DDEFENLR;GS(0.002)GT(0.026)AS(0.973)DDEFENLR;GS(0.001)GT(0.007)AS(0.992)DDEFENLR 204.17 1.1256000000000001e-10 761950000.0 101184.1 111687.59999999999 128397.2 136825.7 150555.8 129581.3 134071.7 134615.9 114227.3 113831.5 True False 118312.56965292926 122775.20681036584 131458.6761970924 129159.79962390487 121055.47176385309 122785.82851315873 121371.4579809496 131082.3752623357 115897.6581656794 134468.24986034152 0.8798550570547954 0.9130423496838841 0.9776187042935797 0.9605226494585153 0.9002531964949427 0.9131213400983792 0.9026030911163474 0.9748202672264837 0.8618960854034354 1.0 17.03690604367707 -11.11260859454517 4.067201799794571 1.0016442985039502 0.9233288182605351 0.2892688177007503 0.03717275189296156 0.0005630018774315195 5.6791640607777964e-05 0.03656094971426035 0.008683122782631501 7.715985546462857e-12 11.11260859454517 -0.07831548024341506 GSGTAS(ph)DDEFENLR ddPTM_PC-9_Lapatinib_30min_R1 5 GSGTASDDEFENLR 14 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 GSGT(0.001)AS(0.999)DDEFENLR;GSGT(0.225)AS(0.775)DDEFENLR;GSGT(0.004)AS(0.996)DDEFENLR;GSGT(0.001)AS(0.999)DDEFENLR;GS(0.007)GT(0.023)AS(0.97)DDEFENLR 235.93 7.0387e-27 998975000.0 266760.0 219640.0 246043.6 215566.90000000002 242609.0 220928.2 220175.9 203841.0 250833.0 183129.9 True False 262955.95348220685 219131.43707464088 225814.84496376195 231420.40893609836 228339.21560764583 211479.61589478806 231575.5307730475 213312.1970181563 222581.54615141204 214783.65920974693 1.2242828642071755 1.020242591456402 1.0513595205268502 1.077458172505129 1.0631126057157878 0.9846168776194827 1.0781803961487706 0.9931490961788966 1.0363057737742054 1.0 17.712524711364296 -4.758467070877452 24.99964053096856 1.0362859850280879 1.2242831190005503 0.7563064661669806 0.03240636773375021 39.622951090754285 333203.680544339 0.007895793685266857 0.053785852836214974 1.743945582081012e-05 4.758467070877452 0.18799713397246243 GSHQIS(ph)LDNPDYQQDFFPK ddPTM_PC-9_AZD4547_30min_R2 2 GSHQISLDNPDYQQDFFPK 19 0 P00533;E9PFD7 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 GS(0.002)HQIS(0.998)LDNPDYQQDFFPK;GS(0.001)HQIS(0.999)LDNPDYQQDFFPK 103.84 0.00015333 15381100.0 62247.0 75563.0 106132.0 87529.0 144424.0 82510.0 96457.0 113172.0 92621.0 87628.0 True False 82040.25118196782 99987.26203499806 104724.62033458299 67350.54135956943 124373.2205397043 77350.63665657365 105041.48613803105 95683.86783384332 97516.75697048091 84560.17039188743 0.9701996909627637 1.1824392213451675 1.2384627401913337 0.7964806722531266 1.4708250936972624 0.9147407851485899 1.2422099630502703 1.131547717919725 1.1532232789804846 1.0 16.367690663357124 -4.749625203928212 24.541960321888595 1.130751728640689 0.970199233603573 0.06319776241083441 0.17842241675510692 1242.2426348962704 2580345.6488368404 0.04067318216228877 0.6394918366550554 1.779814727293143e-05 4.749625203928212 -0.160552495037116 GSHQIS(ph)LDNPDYQQDFFPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GSHQISLDNPDYQQDFFPK 19 0 P00533;E9PFD7 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 GS(0.004)HQIS(0.996)LDNPDYQQDFFPK;GS(0.004)HQIS(0.996)LDNPDYQQDFFPK;GS(0.008)HQIS(0.992)LDNPDYQQDFFPK 113.89 4.691e-05 16275900.0 120036.0 100300.0 103970.0 100654.0 183665.0 109263.0 82891.0 108395.0 78431.0 59134.0 True False 140355.72398093218 110257.12114039247 106449.03910842068 95014.68270467066 147677.16170023446 103533.05593348148 75038.9644011294 105549.74610399568 79577.90499812555 69854.52609551365 2.0092574071581373 1.5783819217331094 1.5238674579635763 1.360179332900419 2.1140671901246915 1.482123803859444 1.0742176433711246 1.5109936607353855 1.1391946871032654 1.0 16.092065974983832 -7.688331679745131 0.5953706544612013 1.014375884745003 1.7121707444818428 0.4717047360529183 0.25390333627279865 0.7673297736078982 0.566140865019868 0.2516031894040301 0.148258926201402 2.049596261567899e-08 7.688331679745131 0.6977948597368397 GSHQIS(ph)LDNPDYQQDFFPK ddPTM_PC-9_Lapatinib_30min_R1 2 GSHQISLDNPDYQQDFFPK 19 0 P00533;E9PFD7 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 GS(0.001)HQIS(0.999)LDNPDYQQDFFPK;GS(0.001)HQIS(0.985)LDNPDY(0.014)QQDFFPK 162.01 1.7405000000000001e-06 13165600.0 149704.0 119620.0 73199.0 69827.0 62195.0 42820.0 39829.0 34662.0 99146.0 72169.0 True False 147569.1935076486 119343.02723943068 67180.86077631134 74962.31051604348 58536.812380074705 40988.68841829529 41891.15073520629 36272.52305985219 87979.13342633507 84643.315490852 1.7434240690110663 1.4099521804805595 0.7936936353062878 0.8856258770268184 0.6915704097909681 0.4842519244502566 0.49491386877128846 0.4285338168703046 1.0394102938446876 1.0 16.369108518680605 -5.0048435090608745 1.1904576936518039 0.6531942447351006 2.0506211536832377 0.7410487235419296 0.20449718588570953 0.5072495114380585 0.8017221120951068 0.06361981593413293 0.7993713699956946 9.889093678395234e-06 5.0048435090608745 1.397426908948137 GSHQISLDNPDY(ph)QQDFFPK ddPTM_PC-9_AZD4547_30min_R2 2 GSHQISLDNPDYQQDFFPK 19 0 P00533;E9PFD7 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 GSHQISLDNPDY(1)QQDFFPK;GSHQISLDNPDY(1)QQDFFPK 157.7 2.2375e-05 41796000.0 143828.0 277840.0 304000.0 252120.0 241180.0 168151.0 242890.0 239300.0 207489.0 182071.0 True False 189562.31219175356 367646.346542671 299968.76136992895 193997.62921517057 207696.32006983526 157636.49138818917 264506.7394597226 202321.68356694913 218456.44494281118 175696.749708099 1.0789175810405751 2.0925051098183394 1.7073096791391664 1.104161741964359 1.1821295522819861 0.897207783582138 1.5054731513199402 1.151539137195677 1.2433721472124712 1.0 17.422727976976155 -5.759543753650048 24.95179968660262 1.1661666442868202 1.6728703331528456 0.3780858706129484 0.27484770264399405 46.11993712362481 607047.7581736582 0.07290132907654676 0.11851963160558793 1.7396274278307342e-06 5.759543753650048 0.5067036888660255 GSHQISLDNPDY(ph)QQDFFPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSHQISLDNPDYQQDFFPK 19 0 P00533;E9PFD7 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 GSHQISLDNPDY(1)QQDFFPK;GSHQISLDNPDY(1)QQDFFPK 162.82 2.1086e-06 18799200.0 44885.0 40903.0 61531.0 86526.0 252404.0 198833.0 254378.0 237858.0 254265.0 212066.0 True False 52483.143980840294 44963.579521490334 62998.13239761694 81678.22874107708 202947.24809727416 188405.84745450827 230281.47430276513 231614.4795313827 257983.14460287988 250511.88708646747 0.20950360715906885 0.17948681016470314 0.2514776170117321 0.3260453214057853 0.8101302116143665 0.7520834625682953 0.9192437012910307 0.9245648269434732 1.0298239640573768 1.0 17.934519537074102 -6.306668144614417 1.2042968497594941 0.9564234953906838 0.1717420578070571 0.9608372368186838 0.06649241492177366 0.08102582908668528 0.24200887450222225 0.027486217923655146 0.03833772022797716 4.935507945336882e-07 6.306668144614417 -0.7846814375836267 down GSHQISLDNPDY(ph)QQDFFPK ddPTM_PC-9_Lapatinib_30min_R1 2 GSHQISLDNPDYQQDFFPK 19 0 P00533;E9PFD7 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 GSHQISLDNPDY(1)QQDFFPK;GSHQISLDNPDY(1)QQDFFPK 228.46 3.8183e-35 16445500.0 70000.0 53751.0 40999.0 32378.0 92633.0 106034.0 103923.0 90367.0 220820.0 54810.0 True False 69001.78716357204 53626.542861951624 37628.22048071671 34759.18612984171 87184.50906348505 101499.1729973267 109303.62444085575 94565.78072095288 195948.92626231318 64283.8354702657 1.0733925046443225 0.8342150475255389 0.5853449814474982 0.5407142538332125 1.3562431119066003 1.5789221700107618 1.700328296238855 1.4710662490680726 3.0481834947908295 1.0 15.972168388974 -6.610690415089187 1.9188331225056954 1.825717703365436 0.7522045868721521 0.46174810150345613 0.5066288068536676 0.2943194587873455 2.21343465689333 0.19041061155146735 0.19418729805270663 2.4508096681946343e-07 6.610690415089187 -1.0735131164932838 GSHS(ph)LDDLLDRPGNSIAPSEYWDGQSR ddPTM_PC-9_AZD4547_30min_R2 2 GSHSLDDLLDRPGNSIAPSEYWDGQSR 27 1 Q6UXY1;B0QYF0 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 GS(0.102)HS(0.887)LDDLLDRPGNS(0.01)IAPS(0.001)EYWDGQSR;GS(0.255)HS(0.745)LDDLLDRPGNSIAPSEYWDGQSR 80.608 9.982899999999999e-06 12922000.0 9051.8 7535.4 13299.3 18978.8 10369.0 15087.599999999999 6441.200000000001 15538.8 10068.0 23113.3 True False 11930.084110863743 9971.07068722157 13122.942592391753 14603.530879537033 8929.44333196833 14144.16998690726 7014.454321742194 13137.635506101555 10600.173925770632 22304.110402140992 0.5348827590863504 0.4470508129418351 0.5883643129354341 0.6547461708284598 0.40034967416190625 0.6341508238566443 0.31449155313851346 0.5890230665662622 0.475256521540223 1.0 14.445021987019208 -10.772008108308535 3.317963287892451 1.0015537523927212 0.5159742196248474 0.6691121531689597 0.10223992637678168 41810626.12126385 62014449.68757747 666127.0573705178 0.024878479821045175 1.6904093712867453e-11 10.772008108308535 -0.4855795327678738 GSHS(ph)LDDLLDRPGNSIAPSEYWDGQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSHSLDDLLDRPGNSIAPSEYWDGQSR 27 1 Q6UXY1;B0QYF0 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 GS(0.197)HS(0.802)LDDLLDRPGNSIAPSEYWDGQSR 58.418 0.013942 0.0 5925.0 4859.6 4458.8 5587.4 6838.0 5181.4 7729.8 4196.2 6999.1 5396.6 True False 6927.985475915753 5342.028972022452 4565.114702093168 5274.356092595209 5498.142986993722 4909.678262666603 6997.5773850942805 4086.0541962414113 7101.4485965036965 6374.960860537909 1.086749491875497 0.8379704736840847 0.716100820375542 0.8273550548748259 0.8624590969692318 0.7701503381861284 1.097665936807624 0.6409536129915371 1.1139595602010468 1.0 12.638200769146335 -8.29706108747845 24.984537525702535 1.0569798724574078 0.8543304768513846 0.25334195990550257 0.13874761565664878 918.5024800677268 644216.1198807941 0.12677537261201952 0.03273832107722603 5.04590317343028e-09 8.29706108747845 -0.20264939560602313 GSHS(ph)LDDLLDRPGNSIAPSEYWDGQSR ddPTM_PC-9_Lapatinib_30min_R1 1 GSHSLDDLLDRPGNSIAPSEYWDGQSR 27 1 Q6UXY1;B0QYF0 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 GS(0.242)HS(0.667)LDDLLDRPGNS(0.09)IAPS(0.001)EYWDGQSR 40.8 0.034091 7644200.0 8305.4 6638.9 8246.1 7385.6 10028.0 10009.0 8205.5 9229.0 9523.1 7302.9 True False 8186.96347297618 6623.528034942801 7568.137488866508 7928.761661639354 9438.172755806558 9580.938402118582 8630.340640180151 9657.813032120934 8450.508195311275 8565.196534497425 0.9558407025457194 0.7733071866203763 0.8835918076584542 0.9256952399989016 1.101921329860104 1.1185894408295392 1.0076056755289093 1.1275646732941687 0.986609958250902 1.0 13.064270635010097 -6.079906320132309 3.3834465196939374 1.0636546258798356 0.8640400101094501 0.6494816230515521 0.0626423785229268 0.13862558127894206 3.049405382708012 0.018285620183374218 0.025220721845949694 8.319432067799063e-07 6.079906320132309 -0.19961461577038553 GSHSLDDLLDRPGNS(ph)IAPSEYWDGQSR ddPTM_PC-9_Lapatinib_30min_R1 1 GSHSLDDLLDRPGNSIAPSEYWDGQSR 27 1 Q6UXY1;B0QYF0 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 GS(0.028)HS(0.087)LDDLLDRPGNS(0.807)IAPS(0.053)EY(0.022)WDGQS(0.002)R 43.303000000000004 0.024405 11605000.0 4080.7 4023.6 3740.9 3821.7 5588.0 4457.8 3565.0 4504.9 4953.5 3641.1 True False 4022.50846969127 4014.283601409247 3433.337642291594 4102.760566817471 5259.324826430701 4267.150285639345 3749.5782563210323 4714.214099945994 4395.584667332525 4270.459283539218 0.9419381388780145 0.94001214737782 0.8039738619041827 0.9607305196965223 1.2315595296044934 0.9992251423839522 0.8780269304461097 1.1039126676882884 1.0293002170224668 1.0 12.06017552323193 -6.003953253263094 24.975476557057334 1.040887647990062 0.8968740629390468 0.3411721164797459 0.09105793659804497 197.83413166677454 1249877.3017784478 0.026720661177938605 0.0386355282319631 9.90938602138186e-07 6.003953253263094 -0.14401358505101514 GSIELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSIELR 6 0 P35590 P35590 TIE1 Tyrosine-protein kinase receptor Tie-1 0 109.7 0.029248000000000003 0.0 13733.0 15695.0 18642.0 19011.0 23647.0 18951.0 17995.0 22892.0 19588.0 13343.0 False True 16057.725660886246 17253.095875358544 19086.495980178694 17945.87530449359 19013.540101409842 17957.176198671175 16290.38332748214 22291.10925607893 19874.437443144758 15761.98027687012 1.018763212415011 1.09460204696973 1.210919925346381 1.1385546098435502 1.206291326814513 1.139271581567856 1.0335239000005239 1.4142327844928193 1.2609099297192659 1.0 13.944161180596605 -5.002077686037802 2.8466050298423715 1.1836782497204468 1.0179689265358842 0.16861689963560744 0.11001322243296405 0.5047326556864524 7.540548143100364 0.029204317002534442 0.15369424534284648 9.952273764363198e-06 5.002077686037802 -0.16570932318456255 GSIRPS(ph)ISNPR ddPTM_PC-9_AZD4547_30min_R2 1 GSIRPSISNPR 11 1 Q92805 Q92805 GOLGA1 Golgin subfamily A member 1 1 GS(0.009)IRPS(0.829)IS(0.162)NPR 61.03 0.028811 3185200.0 7820.3 12923.0 16558.0 13876.0 9557.0 13871.0 12713.0 16414.0 14680.0 12722.0 True False 10306.992727655026 17100.10702696133 16338.430101194985 10677.102582062922 8230.175515828074 13003.644177231025 13844.432371655672 13877.593456196813 15455.954830186018 12276.606652275434 0.8395636530184548 1.3929017611549748 1.33085880846127 0.8697112226923025 0.6703949836417243 1.0592213748919648 1.1277083940039445 1.1304095544695685 1.2589761379478017 1.0 13.583624223445018 -10.489610768907212 15.208047962120517 0.9999999756500698 1.0770718755806141 0.010811337112156982 0.21627939812667016 0.0 0.0 0.22473452852910986 0.05450612934405327 3.238838037691752e-11 10.489610768907212 0.07707189993054431 GSIS(ph)PDAEPNDKVPETAPVQPK ddPTM_PC-9_AZD4547_30min_R2 1 GSISPDAEPNDKVPETAPVQPK 22 1 K7ER94;Q2V2M9-2;Q2V2M9;Q2V2M9-3;Q2V2M9-4 K7ER94 FHOD3 FH1/FH2 domain-containing protein 3 1 GS(0.072)IS(0.927)PDAEPNDKVPET(0.001)APVQPK 60.13399999999999 0.0036666 7716900.0 28582.0 29578.0 36024.0 42132.0 40576.0 49630.0 31505.0 39142.0 42627.0 40410.0 True False 37670.48145746789 39138.510070684984 35546.29822233656 32419.118332911155 34942.72279274251 46526.62825434186 34308.88396672792 33093.503293679496 44880.17619525471 38995.25819984673 0.966027235014332 1.0036735715430862 0.9115543751541637 0.8313605250865752 0.8960762001796376 1.19313553498986 0.8798219463222523 0.848654549844975 1.1509136819981645 1.0 15.251011083332587 GSISSGLEFVSHNPPSEAAT(ph)PPVAR ddPTM_PC-9_Lapatinib_30min_R1 1 GSISSGLEFVSHNPPSEAATPPVAR 25 0 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;F8WB06;F8VRK6 Q99700;F8WB06 ATXN2 Ataxin-2 1 GSISSGLEFVSHNPPS(0.218)EAAT(0.782)PPVAR 73.29899999999999 0.010971 0.0 4368.5 2751.1 5637.9 4774.8 5407.9 5392.1 3944.0 2707.7 4362.5 3169.5 True False 4306.204388915214 2744.7299969770806 5174.373624923355 5125.954720265869 5089.817954340475 5161.492452599021 4148.201021859791 2833.5096269448313 3871.1493108384248 3717.3438519067186 1.158408950171896 0.7383578453656473 1.3919545328768255 1.3789293981068333 1.3692082726567736 1.3884893779604388 1.1159045778700496 0.7622403898663971 1.0413750960522028 1.0 11.86005642739409 -7.544686426399239 9.055221895773531 0.9281893153141612 1.2358338088416638 0.3232654939540247 0.19619768387598668 0.3203216213827386 118.78740998257194 0.09952961345249291 0.05799975003490194 2.8530775312702393e-08 7.544686426399239 0.30764449352750267 GSKPS(ph)PLSVK ddPTM_PC-9_AZD4547_30min_R2 2 GSKPSPLSVK 10 1 Q96S94;Q96S94-3;A0A0A0MSF3 Q96S94 CCNL2 Cyclin-L2 1 GSKPS(0.893)PLS(0.107)VK;GS(0.016)KPS(0.983)PLSVK 134.49 0.00053862 143871000.0 513464.0 425018.0 572149.0 621220.0 598701.0 610067.0 502175.0 627249.0 502126.0 642200.0 True False 676734.8712853304 562396.7568200148 564561.930424484 478007.3267533242 515581.700481509 571919.4140487917 546867.6021581214 530322.0797980989 528667.3552494545 619716.7734704674 1.0920067041199428 0.9075061074602587 0.9109999189837777 0.771331916798769 0.8319634429034524 0.922872251538382 0.8824476366770189 0.8557491139512805 0.853078983628072 1.0 19.24124949176226 -4.607901680284373 1.9584715010023919 0.8695899198329363 1.2448338310995835 0.5457099014462974 0.05764312907941992 1.0145626242256842 2.803522254904559 0.015175322549470597 0.8075451609595362 2.466597685875113e-05 4.607901680284373 0.37524391126664713 GSKPS(ph)PLSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSKPSPLSVK 10 1 Q96S94;Q96S94-3;A0A0A0MSF3 Q96S94 CCNL2 Cyclin-L2 1 GS(0.033)KPS(0.804)PLS(0.163)VK 110.15 0.0085961 23977000.0 41627.0 39591.0 42222.0 56541.0 52224.0 44101.0 44403.0 46047.0 40217.0 36225.0 True False 48673.62892927346 43521.332832196254 43228.7326078267 53373.19107839525 41991.0820931208 41788.26592462654 40196.8263901189 44838.315040829395 40805.097541911025 42792.30574305776 1.137438800833251 1.017036405879035 1.0101987228122136 1.2472613978519733 0.9812764552873633 0.9765369077221526 0.9393470553205717 1.047812550930457 0.9535615534933141 1.0 15.385063796170451 GSLAEAVGS(ph)PPPAATPTPTPPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSLAEAVGSPPPAATPTPTPPTR 23 0 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 GSLAEAVGS(0.985)PPPAAT(0.015)PT(0.001)PTPPTR;GSLAEAVGS(0.946)PPPAAT(0.047)PT(0.007)PTPPTR 153.36 6.8902e-07 27590000.0 48464.0 43241.0 39870.0 46204.0 60783.0 68665.0 69601.0 63795.0 65784.0 53104.0 True False 56667.997992368124 47533.68071018663 40820.65200781703 43615.3396753891 48873.00748441642 65064.086522175945 63007.889412397126 62120.44884638978 66745.9665488991 62731.33482896732 0.9033443676412997 0.7577342462070024 0.6507218779755243 0.6952719847952117 0.7790844498632991 1.0371863869877584 1.004408555695233 0.9902618685822152 1.0639972309034615 1.0 15.936898640917098 -6.720797960663911 5.377892786039082 1.0181825737632462 0.7450738647361542 0.8073704290829404 0.06394877496612969 0.08382573644309768 5.770545719440609 0.022994098909608088 0.022435804637818132 1.9019628915538447e-07 6.720797960663911 -0.27310870902709194 GSLAEAVGS(ph)PPPAATPTPTPPTRK ddPTM_PC-9_AZD4547_30min_R2 2 GSLAEAVGSPPPAATPTPTPPTRK 24 1 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 GSLAEAVGS(1)PPPAATPTPTPPTRK;GSLAEAVGS(1)PPPAATPTPTPPTRK 120.27 6.0934e-06 7083300.0 47115.0 35704.0 62063.0 84751.0 72511.0 62658.0 51970.0 63821.0 49894.0 53102.0 True False 62096.58994712053 47244.61977022574 61240.00406875619 65212.96633989736 62444.09928096791 58739.98535483681 56595.22932076968 53958.93091068215 52531.29497938016 51242.915142990874 1.211808301183549 0.9219736940880884 1.1950921195226487 1.2726240526699883 1.2185899086092324 1.1463045221163888 1.1044498378525778 1.0530027567735436 1.0251425944990469 1.0 15.645064930613607 -7.708297454971012 1.6898795177843668 1.0139127691622594 1.1593948740772484 0.32751371375990423 0.08788582644751207 0.5225863646707585 2.8711511412635753 0.06990924638750591 0.028972670034487027 1.957503490009016e-08 7.708297454971012 0.14548210491498903 GSLAEAVGS(ph)PPPAATPTPTPPTRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSLAEAVGSPPPAATPTPTPPTRK 24 1 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 GSLAEAVGS(1)PPPAATPTPTPPTRK 99.42299999999999 1.8421000000000001e-06 5247900.0 46841.0 30133.0 40579.0 54607.0 67693.0 76315.0 76062.0 75222.0 73065.0 62739.0 True False 54770.25614807932 33124.405097940704 41546.557256714485 51547.54682828265 54429.04258826647 72312.9070551206 68856.856718808 73247.50220429718 74133.43739960044 74113.08405834921 0.7390092700090407 0.44694409251491773 0.5605833002982967 0.6955255942081601 0.7344053115562497 0.9757104022035928 0.9290782807607496 0.9883207956456035 1.0002746254795605 1.0 16.177440640565962 -6.50473925076232 1.37970684123095 0.9881388093003335 0.5730780688696752 0.8455094834571713 0.07494109685152449 0.14675878636428796 0.5749636772975025 0.030623033999930552 0.03464504848972249 3.1279568203121274e-07 6.50473925076232 -0.4150607404306583 GSLAEAVGSPPPAAT(ph)PTPTPPTR ddPTM_PC-9_AZD4547_30min_R2 1 GSLAEAVGSPPPAATPTPTPPTR 23 0 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 GSLAEAVGSPPPAAT(0.884)PT(0.113)PT(0.002)PPTR 142.95 1.638e-05 9010700.0 8897.2 14368.0 17755.0 31272.0 23254.0 18222.0 22161.0 36731.0 28611.0 32731.0 True False 11726.324526743512 19012.175018446203 17519.557099089092 24062.723547583726 20025.583493257942 17082.57545941198 24133.28606845443 31055.067944411156 30123.319049485846 31585.09765254103 0.37126130353439407 0.6019349766650688 0.5546779462839381 0.7618378708937718 0.634019996187882 0.5408428888627381 0.7640719156210334 0.9832189941610887 0.9537193578080458 1.0 14.946956412195785 -7.567058358271444 2.7890282123124344 0.9802031287218637 0.5887681314717598 0.7900321827862063 0.09258617094137431 0.12928741434675403 2.0358899101103773 0.05218750480456837 0.027926346665480162 2.709827474666936e-08 7.567058358271444 -0.3914349972501039 GSLAS(ph)LDSLR ddPTM_PC-9_AZD4547_30min_R2 1 GSLASLDSLR 10 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;E9PKY0 O60716 CTNND1 Catenin delta-1 1 GS(0.004)LAS(0.996)LDSLR 152.67 0.00017102 174680000.0 27891.0 36053.0 43555.0 68140.0 50866.0 51570.0 54801.0 76613.0 49072.0 43141.0 True False 36759.75783116075 47706.427195158765 42977.432241668546 52431.37575250565 43804.13391107156 48345.31974766085 59678.182836396 64774.22124159894 51665.84573752645 41630.646721098434 0.8829975204908572 1.1459448976318958 1.0323508190875055 1.25944177864365 1.0522088259770321 1.161291585776865 1.4335156317941866 1.5559263749984296 1.2410531617166103 1.0 15.345358350087979 -7.096577154237037 4.623351803048849 1.3522412996385498 1.0878383686771929 0.296917279519735 0.16253847236934482 0.24597927391066748 8.749019771209431 0.061346892055645794 0.0474866331710848 8.006133835448566e-08 7.096577154237037 -0.2644029309613569 GSLAS(ph)LDSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GSLASLDSLR 10 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;E9PKY0 O60716 CTNND1 Catenin delta-1 1 GS(0.269)LAS(0.712)LDS(0.018)LR;GS(0.002)LAS(0.987)LDS(0.011)LR;GS(0.205)LAS(0.794)LDS(0.001)LR 137.01 0.00011643 160264000.0 81250.0 94795.0 126325.0 128175.0 192873.0 128467.0 146187.0 135887.0 137790.0 109568.0 True False 95004.0202393509 104205.62112167028 129337.06709023066 120993.7702989567 155080.92020041554 121729.96436677172 132339.1090577732 132320.1102341778 139804.91807693054 129431.81106018936 0.7340082740182892 0.8051005411120439 0.9992680008941957 0.9348070563788315 1.1981669647525726 0.9404949476459379 1.0224620050802802 1.0223152187266027 1.080143412440682 1.0 16.981832713239946 -5.1650831349655375 1.5491498284441019 1.034793925950549 0.7015986930963763 0.6891900245277727 0.06969802680700536 0.31158330435846515 1.1366803486766455 0.019780817737508123 0.12653133169037206 6.837807417967609e-06 5.1650831349655375 -0.33319523285417263 GSLAS(ph)LDSLR ddPTM_PC-9_Lapatinib_30min_R1 2 GSLASLDSLR 10 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;E9PKY0 O60716 CTNND1 Catenin delta-1 1 GS(0.001)LAS(0.999)LDSLR;GS(0.077)LAS(0.923)LDSLR 152.69 0.00017112 117981000.0 385480.0 345430.0 321150.0 272790.0 293340.0 255470.0 258410.0 241930.0 278780.0 228510.0 True False 379982.98451162636 344630.1780581558 294746.2866748493 292851.88660076354 276086.31792862946 244544.14362965646 271789.20539015956 253170.95100888747 247380.8607164554 268007.6490295642 1.4178064912979778 1.285896799237022 1.0997681884905288 1.0926997332395492 1.0301434266085967 0.9124521054347987 1.0141098822152579 0.9446407665064809 0.923036568591244 1.0 18.031914650715173 -4.557952366956487 0.6099940328252138 0.952245809545698 1.869311932652434 0.9416237031502827 0.03748386369715016 0.9532471306416195 0.22146468061546937 0.018093359696796353 0.65214897711148 2.7672451378234308e-05 4.557952366956487 0.9170661231067359 GSLAS(ph)LDSLRK ddPTM_PC-9_AZD4547_30min_R2 2 GSLASLDSLRK 11 1 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;E9PKY0 O60716 CTNND1 Catenin delta-1 1 GSLAS(0.999)LDS(0.001)LRK;GSLAS(0.997)LDS(0.003)LRK 155.88 0.00045363 123524000.0 279240.0 312380.0 415800.0 576920.0 549960.0 524940.0 399710.0 517000.0 441450.0 466030.0 True False 368032.51144718105 413350.7260761577 410286.22032110655 443920.0073251475 473607.54700060695 492115.4188159216 435283.4156591274 437109.5294781124 464784.1457619633 449714.43154849287 0.8183693598178335 0.9191404524263882 0.9123261152824829 0.9871153251555803 1.0531295279314106 1.094284248609568 0.9679107120496991 0.971971319606137 1.033509518833054 1.0 18.778649655951796 -5.4159526937964415 1.2765447554011853 1.0196232041237059 0.8369351807162017 0.7066517779357177 0.04058978851056587 0.3610030088469299 0.9891212107089629 0.01424960013901384 0.0640921144788645 3.837490436786646e-06 5.4159526937964415 -0.18268802340750423 GSLAS(ph)LDSLRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GSLASLDSLRK 11 1 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;E9PKY0 O60716 CTNND1 Catenin delta-1 1 GS(0.009)LAS(0.99)LDS(0.002)LRK;GSLAS(1)LDSLRK;GS(0.002)LAS(0.997)LDS(0.001)LRK;GSLAS(0.999)LDS(0.001)LRK 127.71 0.00050881 153954000.0 434172.0 542663.0 739319.0 778213.0 1155620.0 898835.0 861820.0 741270.0 796581.0 800576.0 True False 507668.744312118 596534.996305173 756947.1688429208 734612.2486105856 929184.5566875834 851698.5102914149 780182.1705635281 721812.4479404861 808229.4901418057 945714.0914438696 0.5368099607536083 0.630777316000878 0.8003974728633378 0.7767804828719596 0.9825216363953616 0.9005877336469457 0.8249662108474924 0.763245947661051 0.854623503502883 1.0 19.85104456793789 -5.160093821283444 1.3379284217032459 0.8694880890632771 0.493662693359379 0.7284130478433755 0.0711379194398951 0.4009572375906336 1.0036697423010292 0.022663887717698627 0.170179774795869 6.916815297869619e-06 5.160093821283444 -0.3758253957038981 GSLAS(ph)LDSLRK ddPTM_PC-9_Lapatinib_30min_R1 4 GSLASLDSLRK 11 1 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;E9PKY0 O60716 CTNND1 Catenin delta-1 1 GSLAS(1)LDSLRK;GSLAS(0.997)LDS(0.003)LRK;GS(0.009)LAS(0.989)LDS(0.002)LRK;GS(0.001)LAS(0.999)LDSLRK 132.79 0.00013306 115633500.0 524002.0 436983.0 400908.0 332523.0 361444.0 350383.0 311692.0 343572.0 419197.0 350423.0 True False 516529.63538980245 435971.19271165505 367946.89178963326 356977.8506842107 340184.5745462452 335397.935872666 327829.88663933065 359535.60939125076 371982.6195198931 410993.14864070213 1.256784053695655 1.060774842971383 0.8952628359050805 0.8685737265082426 0.8277134927220914 0.816066975768195 0.7976529237131533 0.8747970874462521 0.90508228847651 1.0 18.64875481845455 -4.899153774315 1.5510469715488837 0.856631765763186 1.355971273846678 0.8350228017428296 0.05425063715947913 0.30036502876172755 0.8207342804820735 0.015192227844923564 0.2155288528341694 1.2613808277481542e-05 4.899153774315 0.49933950808349203 GSLASLDS(ph)LR ddPTM_PC-9_AZD4547_30min_R2 2 GSLASLDSLR 10 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;E9PKY0 O60716 CTNND1 Catenin delta-1 1 GSLAS(0.012)LDS(0.988)LR;GSLAS(0.001)LDS(0.999)LR 108.98 0.0058892 2129800.0 16467.0 17137.0 20323.3 33800.0 32418.0 29997.0 20128.2 23189.0 21203.4 21279.4 True False 21703.163465122238 22676.200117699944 20053.79976299167 26007.932204794382 27917.320275412236 28121.282847984916 21919.57080650985 19605.672880208844 22324.168436400978 20534.414682945284 1.056916586141978 1.1043022393296413 0.9765946618214162 1.2665533742432449 1.3595381561374025 1.369470875220069 1.0674553497117694 0.9547714499255827 1.0871587420966111 1.0 14.325756204585092 -7.5079139779932875 24.35607195117312 1.0148017018082462 1.1893351052419214 0.3066537716739388 0.1210217529123223 686.4977484651495 1117323.9059116864 0.059305471122078526 0.03840787921476168 3.105174578434094e-08 7.5079139779932875 0.17453340343367518 GSLASLDS(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 2 GSLASLDSLR 10 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;E9PKY0 O60716 CTNND1 Catenin delta-1 1 GSLAS(0.002)LDS(0.998)LR;GSLASLDS(1)LR 99.75200000000001 0.004252399999999999 2732200.0 21291.4 18513.4 26236.0 17720.5 20014.9 16442.7 12720.1 13922.7 26199.0 13006.7 True False 20987.780731635434 18470.53335975991 24078.977353888706 19023.7246838551 18837.66293280742 15739.48405080579 13378.684538072692 14569.599469315213 23248.19273229934 15254.890764661663 1.3758066875348693 1.2107942065732364 1.5784431186926793 1.2470574176725038 1.2348605587163783 1.0317664212494198 0.8770095272700837 0.9550772728616357 1.5239829042994109 1.0 13.89698422883048 -6.424592980640927 2.198350355894966 1.0649896810226103 1.365719567980224 0.32730617545386487 0.18615170655032237 0.3713535536533723 3.542248146108711 0.06624498725250706 0.07615213427100068 3.7618980297442316e-07 6.424592980640927 0.3007298869576138 GSLDESS(ph)LGFGYPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSLDESSLGFGYPK 14 0 Q2KJU6;Q9BUZ4 Q2KJU6 TRAF4 TNF receptor-associated factor 4 1 GS(0.087)LDES(0.159)S(0.753)LGFGYPK 85.271 0.006959600000000001 6998600.0 14616.0 18061.0 14565.0 21300.0 24533.0 18616.0 19709.0 14429.0 18647.0 17235.0 True False 17090.200120841295 19853.97671900928 14912.2848380701 20106.630055531718 19725.93476161407 17639.74418840497 17842.020839196764 14050.254038789213 18919.677098341865 20359.569067815057 0.8394185586107484 0.97516684429215 0.7324459957084176 0.9875764063845933 0.9688778134699003 0.8664104888295667 0.8763457016092694 0.6901056693287396 0.9292768935984302 1.0 14.313419405093429 -8.52591383597083 24.90237279752279 1.0000000156280027 0.8698515093520502 0.16899542383724686 0.09323395405859278 564.4543237373601 4631256.271908679 0.09017318640067161 0.023282616658201024 2.9791074257408516e-09 8.52591383597083 -0.13014850627595242 GSLDQDRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSLDQDRR 8 1 A0A2R8Y5T7;A0A2R8Y430;P48637-2;P48637;A0A2R8Y7I7;A0A2R8Y6Q7 A0A2R8Y5T7 GSS Glutathione synthetase 0 ; 84.49799999999999 0.0088152 3346140.0 16503.8 19898.0 21408.2 19321.7 27000.7 24330.9 17834.5 18032.5 21237.5 20207.8 False True 19297.56737509171 21873.341938699225 21918.65267905063 18239.167790796582 21710.106661146743 23054.944771898507 16145.087049401514 17559.16598201308 21548.058260097343 23871.31417514322 0.8083998741546423 0.9163023777499252 0.9182005028392671 0.7640621566528041 0.9094642423898511 0.9658012375332572 0.6763384257333059 0.7355760078050974 0.902675826810363 1.0 14.54299037210121 -7.237086071388112 24.98393242393853 0.8066121694251237 0.8797600070430877 0.04358852572240146 0.09910660568386279 1773.192296220866 1819111.2229318249 0.03731729873857679 0.02889349894290896 5.7931387274707084e-08 7.237086071388112 0.07314783761796395 GSLDQDRR ddPTM_PC-9_Lapatinib_30min_R1 1 GSLDQDRR 8 1 A0A2R8Y5T7;A0A2R8Y430;P48637-2;P48637;A0A2R8Y7I7;A0A2R8Y6Q7 A0A2R8Y5T7 GSS Glutathione synthetase 0 66.692 0.030601 335380.0 1979.6 3278.5 2993.8 3026.5 3063.0 3082.5 2778.4 3818.0 2747.1 2472.5 False True 1951.370540985822 3270.9088346804397 2747.6613204021955 3249.078906108036 2882.840362089698 2950.66866065846 2922.2519571843904 3995.3982182942605 2437.6926697545546 2899.8683306008406 0.6729169460537217 1.127950810788268 0.9475124409641357 1.1204229074203655 0.9941280201133772 1.0175181505730964 1.0077188423858239 1.3777860795032824 0.8406218461820557 1.0 11.501771680384467 -4.7547420728760805 24.990494683459534 1.055189497380793 0.6729162942744455 0.4100691432085186 0.1347956995369651 216.54269963007232 807939.6214338284 0.0315133203398185 0.29846695412759605 1.758967953385323e-05 4.7547420728760805 -0.3822732031063474 GSLGS(ph)QGAKDEPEEELQK ddPTM_PC-9_AZD4547_30min_R2 1 GSLGSQGAKDEPEEELQK 18 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 GS(0.257)LGS(0.743)QGAKDEPEEELQK 65.887 0.0068447000000000004 17834000.0 53546.0 54220.0 56281.0 71660.0 64107.0 66059.0 52962.0 63044.0 59094.0 56524.0 True False 70572.51417401069 71745.55467011081 55534.677166647874 55139.894135963514 55206.84961736847 61928.32028719665 57675.51539901102 53301.99840699841 62217.58819720796 54545.1119645666 1.293837552663853 1.3153434301632363 1.0181421426492647 1.0109044082957113 1.0121319331644556 1.1353596693948727 1.0573910900848087 0.9772094416384051 1.1406629477197796 1.0 15.735162295430166 -5.259340109870454 24.999856110448945 1.0445857622128327 1.3045905184554252 0.7993351362095991 0.05223061304744129 71.98818980330475 857281.1218512895 0.013353245210628166 0.031966543085178795 5.503765101777262e-06 5.259340109870454 0.26000475624259245 GSLLPTS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 GSLLPTSPR 9 0 Q9H0E9-3;H7C128;H7C179;H7C127;Q9H0E9-4;Q9H0E9-2 Q9H0E9-3 BRD8 Bromodomain-containing protein 8 1 GSLLPT(0.034)S(0.966)PR 67.207 0.046374 29200000.0 59907.0 76976.0 112620.0 171100.0 141540.0 109370.0 91256.0 139890.0 97954.0 115990.0 True False 78956.17985699153 101856.98665227709 111126.58521539914 131655.53846864856 121889.61415824061 102531.07661046491 99377.60721370322 118273.21485240477 103131.64846294554 111929.2254046081 0.7054116525114531 0.9100124322676109 0.9928290382935508 1.176239163567269 1.0889882755609817 0.9160348983014022 0.8878611180812466 1.0566785790294184 0.9214005376177616 1.0 16.77222725642818 -4.812895691460904 2.3022855384355565 1.0080604684560692 0.6438268677898328 0.5499767570237907 0.08244897431150132 0.4553114362656461 3.0772899521376815 0.02386537140284254 0.33204715114211186 1.538524117556754e-05 4.812895691460904 -0.36423360066623645 GSLLPTS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 GSLLPTSPR 9 0 Q9H0E9-3;H7C128;H7C179;H7C127;Q9H0E9-4;Q9H0E9-2 Q9H0E9-3 BRD8 Bromodomain-containing protein 8 1 GSLLPT(0.104)S(0.896)PR;GSLLPT(0.106)S(0.894)PR 86.882 0.01132 14348100.0 104477.0 95047.0 113122.0 93543.0 107924.0 105836.0 87051.0 90804.0 112049.0 80396.0 True False 102987.13882126496 94826.92451117032 103821.54582354784 100422.46427030032 101576.12250674776 101309.640995766 91558.07483618577 95023.08533629982 99428.86169172145 94292.34147906373 1.0922110661991757 1.0056694215428439 1.101060215442841 1.0650118842641922 1.0772467934662677 1.0744206730539232 0.9710022404790418 1.0077497689183839 1.0544744157593988 1.0 16.524852978033437 -7.240374100057535 24.55849473329975 1.0089524186789118 1.0679931176436352 0.4894012447199253 0.03048619146056359 561.5373176584208 654656.9102802853 0.011473735125399995 0.008878541962892858 5.749444684057088e-08 7.240374100057535 0.059040698964723415 GSLLTILGSPS(ph)PER ddPTM_PC-9_AZD4547_30min_R2 1 GSLLTILGSPSPER 14 0 Q96A19 Q96A19 CCDC102A Coiled-coil domain-containing protein 102A 1 GSLLTILGS(0.008)PS(0.992)PER 99.069 0.002297 2908200.0 9975.5 7184.2 9986.4 14237.0 12032.0 8992.5 9841.6 11858.0 9495.2 10510.0 True False 13147.501496710194 9506.352155311897 9853.973811002159 10954.87960945733 10361.564487437841 8430.19755343883 10717.483334294539 10025.618569732038 9997.096887165011 10142.04809899503 1.296335944020318 0.9373207524280895 0.9715960439961415 1.080144710666758 1.02164418727856 0.831212539237925 1.0567375770340242 0.9885201166345751 0.9857078954452619 1.0 13.308061401111306 -4.7558753227398425 24.999556928214684 0.9865158255284094 1.29633643591056 0.6743984289639341 0.06471464060674845 107.63976363830783 483579.9350172817 0.016231310397533606 0.13819605578660324 1.754384078137295e-05 4.7558753227398425 0.3098206103821506 GSLLTILGSPS(ph)PER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSLLTILGSPSPER 14 0 Q96A19 Q96A19 CCDC102A Coiled-coil domain-containing protein 102A 1 GSLLTILGS(0.003)PS(0.997)PER;GSLLTILGS(0.01)PS(0.99)PER 77.633 0.014898 5225800.0 11675.6 12044.4 14067.6 15912.7 16711.5 16093.1 14909.0 14722.8 11956.3 10735.5 True False 13652.048476388527 13240.088433333449 14403.024935670092 15021.163008669468 13437.001539506524 15249.149505716594 13496.711588187356 14336.342100096042 12131.138268402672 12681.761167828763 1.0765104543224802 1.0440260038109737 1.1357275022816113 1.1844697916859785 1.0595532719535568 1.2024473023826383 1.064261612371787 1.130469333901717 0.9565815116576302 1.0 13.63046749187669 -8.26040481344882 24.997502418054125 0.9782907438714429 1.1127627121359378 0.522684631655975 0.0511774219152773 69.20437978255826 1672255.0812031098 0.03895762552154726 0.012806183146560004 5.490288758982897e-09 8.26040481344882 0.13447196826449492 GSLLTILGSPS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 2 GSLLTILGSPSPER 14 0 Q96A19 Q96A19 CCDC102A Coiled-coil domain-containing protein 102A 1 GSLLTILGS(0.001)PS(0.999)PER;GSLLTILGSPS(1)PER 128.22 2.6351e-05 4365000.0 40025.0 30221.0 37738.0 32575.0 35757.0 30585.0 27972.0 34999.0 35234.0 29033.0 True False 39454.23616031396 30151.02513127271 34635.327312892696 34970.67416701446 33653.84356096679 29276.950847117292 29420.25329195286 36625.18131013117 31265.575889531472 34051.315365959235 1.1586699584520594 0.8854584560752209 1.0171509364809235 1.0269992154832968 0.9883272701591493 0.8597891309768659 0.8639975570918472 1.0755878566366632 0.9181899598741304 1.0 15.055422908632416 -4.747477920547012 24.829959461012493 0.9605735391436754 1.1586705017899217 0.41607652656828353 0.07077390600272083 696.4455026552987 1238525.7588795982 0.018080533901905945 0.36366668027733895 1.7886364607507568e-05 4.747477920547012 0.19809696264624632 GSLPQLVS(ph)PIVSR ddPTM_PC-9_AZD4547_30min_R2 1 GSLPQLVSPIVSR 13 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 GSLPQLVS(0.993)PIVS(0.007)R 122.16 0.00018616 29698000.0 54435.0 55257.0 97584.0 125960.0 91186.0 103730.0 62379.0 131810.0 88381.0 77654.0 True False 71744.19768166202 73117.74464047064 96289.97239974714 96921.86806260057 78526.39788493239 97243.74670205261 67930.61015586485 111441.79319247624 93052.63922661237 74935.35709603813 0.9574145031392018 0.9757442611071031 1.2849738245237246 1.2934063680831498 1.0479218479507868 1.2977017855192676 0.9065228056337157 1.4871723777822394 1.2417721464562435 1.0 16.193358972348236 -5.246174472784175 22.752937248797167 1.2039692292615114 0.9665791579537846 0.24179525435799676 0.16111369508536935 329.8642014513648 491666.67781845026 0.0395349312121676 0.10346038230791918 5.67316646721643e-06 5.246174472784175 -0.23739007130772682 GSLPQLVS(ph)PIVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSLPQLVSPIVSR 13 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 GSLPQLVS(0.999)PIVS(0.001)R 109.14 0.00081978 13423000.0 11733.0 16647.0 25077.0 17480.0 21431.0 22685.0 22906.0 17154.0 16735.0 14685.0 True False 13719.165162686848 18299.604143809727 25674.930785052104 16500.652270924627 17231.74939372075 21495.358665339856 20736.177854921145 16703.725676165388 16979.717715490482 17347.27425360395 0.7908542265558894 1.0548979555106721 1.480055621978655 0.9511956766058831 0.9933404603977366 1.2391202416641407 1.195356547188567 0.9629020347502223 0.9788118563908039 1.0 14.08242137205101 -7.782716472227712 24.887397705047018 0.97814261448737 1.1089643201540393 0.08896071938928196 0.17469987181635646 595.9861344602741 697102.8516443832 0.09830528848625372 0.04729891078198539 1.6492387404120707e-08 7.782716472227712 0.13082170566666929 GSLPQLVS(ph)PIVSR ddPTM_PC-9_Lapatinib_30min_R1 3 GSLPQLVSPIVSR 13 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 GSLPQLVS(1)PIVSR;GSLPQLVS(1)PIVSR;GSLPQLVS(0.983)PIVS(0.016)R 134.88 4.8518999999999994e-05 40407500.0 166765.0 129302.0 154599.0 119564.0 142413.0 127007.0 119605.0 140615.0 161093.0 104761.0 True False 164386.9005190448 129002.60916329139 141888.46698939806 128357.13541381156 134036.54733473057 121575.20667777739 125797.56166824048 147148.48624029505 142949.00995550587 122868.79926474174 1.3379059737113996 1.0499216231887585 1.1547965621742198 1.0446682655150252 1.0908916513941511 0.9894717569089522 1.0238365021960394 1.197606610635452 1.163428069704644 1.0 16.906759085340546 -4.756957797858478 24.997157078964463 1.0826604448544679 1.337906355339384 0.5635705770147394 0.06819075417870568 107.57937386770259 599976.8099396721 0.017639985519444304 0.13675252133939308 1.750016736527192e-05 4.756957797858478 0.25524591048491607 GSLPQLVSPIVS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 GSLPQLVSPIVSR 13 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 GSLPQLVS(0.421)PIVS(0.579)R 118.52 0.000242 20310000.0 87879.0 97296.0 116900.0 176070.0 139550.0 125610.0 108010.0 153140.0 100090.0 122230.0 True False 115822.69400324738 128745.02927301949 115349.82961889703 135479.78175438303 120175.89130834019 117755.58684319704 117622.6807569048 129475.73180711469 105380.55306221524 117950.76490391664 0.9819579728677232 1.091515001008225 0.9779489748359127 1.148612998523118 1.018864874731725 0.9983452582026188 0.9972184652869432 1.0977099801988257 0.8934283143314826 1.0 16.847825248838767 -6.508629469317463 24.74695168166157 1.0040135800117016 1.0523154147530014 0.12259984814649261 0.06510982866785402 1317.4228781640143 2287996.968149911 0.019487414798954848 0.021259726117843037 3.100063078186497e-07 6.508629469317463 0.04830183474129979 GSLPQLVSPIVS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GSLPQLVSPIVSR 13 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 GSLPQLVS(0.024)PIVS(0.976)R;GSLPQLVS(0.001)PIVS(0.999)R;GSLPQLVS(0.317)PIVS(0.683)R 144.88 5.3568999999999995e-05 29126600.0 95444.0 94402.0 127563.0 149766.0 179182.0 151242.0 154444.0 142204.0 139619.0 119311.0 True False 111600.78409507252 103773.60667891648 130604.58570537163 141375.09656792285 144072.57336874955 143310.6032736754 139813.9462422699 138471.29567759283 141660.66374180256 140941.13983464395 0.7918254686034585 0.7362903890281187 0.9266604900357734 1.0030789926474841 1.0222180233378237 1.0168117232612945 0.9920023806129531 0.9824760594390765 1.0051051375631188 1.0 17.10473326118946 -5.4246272967378815 3.1155288721729737 1.0025370172534038 0.7630776572820615 0.9633365100141802 0.01836907820602095 0.042410068016062244 0.7772905513537808 0.005263138570366903 0.012369322433672099 3.761600792356194e-06 5.4246272967378815 -0.23945935997134238 GSLPS(ph)GTTIEWLEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSLPSGTTIEWLEPK 15 0 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 GS(0.007)LPS(0.455)GT(0.447)T(0.091)IEWLEPK 146.84 1.3593e-09 0.0 4997.3 5706.5 5520.5 7035.9 7785.0 6722.4 9081.6 4516.2 5218.2 6095.0 True False 5843.244188825956 6273.003607055343 5652.129656612839 6641.701333695572 6259.585135090103 6369.865509891142 8221.325102909801 4397.654535309438 5294.506303135493 7199.975252006548 0.8115644824192296 0.871253495670993 0.7850207061527965 0.9224616892738081 0.8693898126032629 0.8847065839727625 1.141854633544555 0.6107874515379569 0.7353506252205487 1.0 12.813776232346372 -11.356698611219988 4.79860947769979 1.0235267824291892 0.852430670998349 0.10888073925502639 0.1298720719583655 0.036242032901754324 0.0012550932298055159 0.13941792796897667 0.03112004511288646 4.39846751454354e-12 11.356698611219988 -0.17109611143084014 GSLS(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSLSPAR 7 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 GS(0.029)LS(0.971)PAR 77.318 0.02997 20849000.0 102100.0 93987.0 119660.0 128160.0 140700.0 115050.0 123460.0 115660.0 117770.0 92626.0 True False 119383.51343308012 103317.4082215563 122513.14821307726 120979.61070032638 113130.84502340092 109016.57546605026 111764.97502700452 112624.04755189973 119492.1634510498 109418.3605729875 1.0910738637273345 0.944241968902819 1.119676328282719 1.1056609701223494 1.0339292640738937 0.9963279918942924 1.0214462585778894 1.0292975233966686 1.092066841664499 1.0 16.739495319377603 -6.496386737029601 24.40871025975043 1.0276898203079432 1.0615917480327064 0.1083275389351247 0.05088451502068028 1463.6745149601365 1348572.1764136518 0.016204122553272835 0.018316841776156233 3.188697071895371e-07 6.496386737029601 0.03390192772476319 GSLS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 1 GSLSPAR 7 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 GS(0.094)LS(0.906)PAR 77.318 0.02997 20928000.0 186920.0 144620.0 174400.0 139650.0 164060.0 155640.0 128690.0 142340.0 156860.0 122800.0 True False 184254.4865230698 144285.14127542643 160061.50520346814 149920.3268587436 154410.31335437018 148983.64001456063 135352.93851499414 148953.63603771728 139192.774990972 144025.8163792857 1.2793156890556596 1.0018005445319456 1.1113389892680987 1.0409267631848373 1.0721016359160038 1.0344231594023303 0.9397824773202331 1.0342148358003704 0.9664432286529373 1.0 17.1359679098829 -2.782501036807947 1.6608617328168707 1.0229792392386983 199.99565806156448 0.7006172318294748 0.04934297877097153 585.2507716079228 2.6553225852889635 0.013694739373937951 442735.4281765073 0.0016500570620707367 2.782501036807947 198.97267882232578 GSLS(ph)PGGER ddPTM_PC-9_Lapatinib_30min_R1 2 GSLSPGGER 9 0 E7EWN3;Q9C0A6;H0Y3R4;Q9C0A6-2;Q9C0A6-3;H7C1F2 E7EWN3 SETD5 SET domain-containing protein 5 1 GS(0.009)LS(0.991)PGGER;GS(0.005)LS(0.995)PGGER 80.102 0.019178 10665900.0 121941.0 190939.0 169963.0 136766.0 285560.0 161207.0 284120.0 352240.0 225820.0 218060.0 True False 120202.09897875962 190496.8924767573 155989.2982161531 146824.22787800184 268763.9222325607 154312.55240187122 298830.34339016303 368606.356315341 200385.7736099791 255751.3804533144 0.469995895098215 0.7448518640998348 0.6099255376047827 0.5740896788817277 1.0508796541241803 0.6033693821255439 1.168440783625457 1.441268296038103 0.783517857283113 1.0 17.964382501573695 -6.774594118085748 1.0674012442318177 1.1170153476222022 0.6096744317518948 0.44586392733699254 0.21931934661925387 0.4499005609191868 1.0922667612748822 0.11973571162105237 0.10698600303116228 1.6803737242205533e-07 6.774594118085748 -0.5073409158703074 GSLS(ph)PVTKPR ddPTM_PC-9_AZD4547_30min_R2 1 GSLSPVTKPR 10 1 F5H4N6;Q9Y3R0-3;Q9Y3R0-2;Q9Y3R0;F5H4P8;H0YFK8;F5H4Q7 F5H4N6 GRIP1 Glutamate receptor-interacting protein 1 1 GS(0.082)LS(0.883)PVT(0.036)KPR 57.567 0.038076 56189000.0 130810.0 137590.0 182290.0 236130.0 212430.0 186970.0 186350.0 201640.0 172490.0 153720.0 True False 172404.8589829745 182063.27678090316 179872.71549382992 181693.8766721331 182937.76130871143 175278.73634322546 202934.78899221565 170481.17122624122 181607.4692546855 148338.30958872626 1.162240957585223 1.227351702238489 1.2125843687482623 1.2248614479690814 1.2332469057785107 1.1816147617509771 1.3680538058904692 1.149272711135154 1.224278945595371 1.0 17.178531708211928 -9.350601856084715 1.3035583917276217 0.9997202821690424 1.2239177307234355 0.575368719194745 0.05672288871266265 5.754522190091384 8.349859254535623 0.05589111939624074 0.015486386910582144 4.4606499566160705e-10 9.350601856084715 0.22419744855439305 GSLSLS(ph)FEREPSTSDLGTTDVQK ddPTM_PC-9_AZD4547_30min_R2 1 GSLSLSFEREPSTSDLGTTDVQK 23 1 P57078-2;P57078 P57078-2 RIPK4 Receptor-interacting serine/threonine-protein kinase 4 1 GS(0.038)LS(0.243)LS(0.689)FEREPS(0.009)T(0.009)S(0.009)DLGT(0.003)T(0.001)DVQK 52.769 0.0085348 4274700.0 7904.0 8098.5 12468.0 12446.0 10655.0 6971.9 9804.3 12368.0 10252.0 13640.0 True False 10417.307586586878 10716.181750200916 12302.66617355352 9576.766988783167 9175.737168687676 6535.945990861289 10676.86370655421 10456.809788366163 10793.899790127187 13162.467751692882 0.7914403121897156 0.8141468569845242 0.9346777827410989 0.7275814208586727 0.6971137435461177 0.4965593165476643 0.811159723842895 0.7944414364868068 0.8200513759085135 1.0 13.6841423761733 -10.192907767209475 6.753753995606458 0.9999776398338033 0.7628587281975356 0.2992071268918396 0.10772784587210299 4.147751376305435e-10 1.251974782788485e-10 0.11348819557985403 0.027524930449205506 6.413457671918173e-11 10.192907767209475 -0.23711891163626764 GSLSLS(ph)FEREPSTSDLGTTDVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSLSLSFEREPSTSDLGTTDVQK 23 1 P57078-2;P57078 P57078-2 RIPK4 Receptor-interacting serine/threonine-protein kinase 4 1 GS(0.029)LS(0.033)LS(0.486)FEREPS(0.13)T(0.13)S(0.13)DLGT(0.045)T(0.016)DVQK 47.507 0.02196 3547000.0 7516.1 7278.9 5264.2 7409.2 8751.1 7175.9 7481.9 7176.6 6193.7 8216.4 True False 8788.427280258298 8001.5010874257605 5389.718492589674 6994.086544950501 7036.384775296979 6799.583171550017 6773.160267734853 6988.221854236239 6284.271145170806 9705.968279013388 0.9054663097612804 0.8243897834208781 0.5552994134797995 0.7205964767135474 0.7249544376228094 0.700556912621725 0.6978345769355166 0.7199922412013685 0.6474646284141372 1.0 13.244656429764728 -10.730175347759058 5.237936448719459 1.0000198222546874 0.7186261230149183 0.4693070498891363 0.08867883653857749 2.110834424560309e-05 3.1944683632951404e-06 0.08829242266173047 0.021412550516907155 1.861335464896882e-11 10.730175347759058 -0.2813936992397691 GSLSLS(ph)PPLNK ddPTM_PC-9_AZD4547_30min_R2 1 GSLSLSPPLNK 11 0 Q9H7X7-3;Q9H7X7-2;Q9H7X7 Q9H7X7-3 IFT22 Intraflagellar transport protein 22 homolog 1 GSLS(0.002)LS(0.998)PPLNK 116.01 0.0013029 4527300.0 43929.0 57625.0 54749.0 44261.0 45650.0 58960.0 57324.0 62463.0 53497.0 41130.0 True False 57897.508220037285 76251.15433170681 54022.99248763888 34057.31027563328 39312.285476357836 55273.22187942765 62425.72494869736 52810.77860694657 56324.74220370989 39690.05121899766 1.4587410809972605 1.9211654303738759 1.361121762971693 0.8580817920268073 0.9904821049346743 1.392621581021571 1.572830546482572 1.3305797544969826 1.4191148782582077 1.0 15.27648980364951 -5.467546773312106 8.054474776919351 1.238530340374149 1.6805348359277603 0.3818026451692703 0.23386651032614572 0.36059491149223627 48.09918467220364 0.06614060645804262 0.13721413318268022 3.4076362274158186e-06 5.467546773312106 0.4420044955536113 GSLSLS(ph)PPLNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSLSLSPPLNK 11 0 Q9H7X7-3;Q9H7X7-2;Q9H7X7 Q9H7X7-3 IFT22 Intraflagellar transport protein 22 homolog 1 GSLS(0.003)LS(0.997)PPLNK;GSLS(0.017)LS(0.983)PPLNK 115.92 0.0013119000000000002 11799200.0 151298.0 243088.0 209166.0 171024.0 208239.0 140070.0 181659.0 116134.0 129987.0 131079.0 True False 176909.76312828722 267220.17012737616 214153.3107064724 161442.07974728924 167436.0628061693 132724.4826208574 164450.9444227327 113085.60555414435 131887.81396375597 154842.5850792072 1.142513624645261 1.7257537388095403 1.3830388494026096 1.0426206696607796 1.0813308413865612 0.8571574967762541 1.0620524343391096 0.7303262568000738 0.85175414693762 1.0 17.24044277300905 -5.859942925071879 2.1291488529857694 0.9184858024066971 1.464943161755307 0.6364825650873869 0.16448893630635059 0.18328714504585064 1.6937650883612139 0.049758260000888385 0.08763976283373776 1.3805656864564222e-06 5.859942925071879 0.54645735934861 GSLSLS(ph)PPLNK ddPTM_PC-9_Lapatinib_30min_R1 1 GSLSLSPPLNK 11 0 Q9H7X7-3;Q9H7X7-2;Q9H7X7 Q9H7X7-3 IFT22 Intraflagellar transport protein 22 homolog 1 GSLS(0.006)LS(0.994)PPLNK 101.53 0.0036944000000000005 4075700.0 23918.0 39224.0 32298.0 29261.0 41695.0 35844.0 36223.0 35068.0 33706.0 35549.0 True False 23576.924933975988 39133.179237915356 29642.583113885412 31412.951551834518 39242.58207552398 34311.03567644506 38098.44969949977 36697.387302028044 29909.6753400848 41693.59728393497 0.5654807085465963 0.9385896585371832 0.7109624749339402 0.7534238731647723 0.9412136306752452 0.8229329660088002 0.9137721900091251 0.8801684117615818 0.717368547894747 1.0 15.347538231422362 -4.749439640273357 24.992426374131785 0.8455552716305373 0.565480072560555 0.44820278671033364 0.0954241893888805 521.9837183779254 1087093.1864562558 0.022993726128773137 0.3745170121512786 1.780575362087246e-05 4.749439640273357 -0.28007519906998235 GSNMDFREPTEEER ddPTM_PC-9_Lapatinib_30min_R1 1 GSNMDFREPTEEER 14 1 Q15056;Q15056-2 Q15056;Q15056-2 EIF4H Eukaryotic translation initiation factor 4H 0 100.02 0.0026712 3795700.0 46630.0 27749.0 33925.0 34485.0 33431.0 25785.0 27458.0 21919.0 35406.0 27550.0 False True 45965.047649105305 27684.748895393477 31135.817454287022 37021.14193858764 31464.65430787487 24682.235657770772 28879.640886974164 22937.43675924356 31418.203438291188 32311.98079193249 1.4225388392339493 0.856795164421046 0.9635997760329467 1.1457404043713382 0.9737767087225684 0.7638725653096861 0.8937750078814328 0.7098740528148146 0.9723391345335147 1.0 14.979781573083875 -6.540434859568017 5.984285907050089 0.8522029838370996 1.0697150094075953 0.30760495766992246 0.1590635515013962 0.20699667564201943 26.169425839463695 0.05060375184527966 0.05198193112147557 2.881145164328677e-07 6.540434859568017 0.21751202557049576 GSNPLDGRDS(ph)PSAGGPVGQLEPIPIPAPASPGTRPTLK ddPTM_PC-9_AZD4547_30min_R2 1 GSNPLDGRDSPSAGGPVGQLEPIPIPAPASPGTRPTLK 38 2 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 GS(0.013)NPLDGRDS(0.814)PS(0.173)AGGPVGQLEPIPIPAPASPGTRPTLK 71.44 4.1869999999999996e-07 5886900.0 21088.0 18934.0 32745.0 41196.0 36581.0 28914.0 28724.0 35798.0 27735.0 33599.0 True False 27793.545342351215 25054.045225449656 32310.77990479708 31698.89867185529 31502.359584022917 27106.003009188782 31280.380354238758 30266.241656204053 29201.015477875273 32422.709236739676 0.8572246427469133 0.7727313915229439 0.996547810637127 0.9776758148247463 0.9716140423060677 0.8360190634061423 0.9647676301767376 0.9334889763594453 0.9006346528496221 1.0 14.984717026823882 -5.25859433415585 24.996720614406886 0.9437789111458048 0.8149780129443442 0.5239693507941742 0.05045665956067769 191.4782462003112 1682313.9577310397 0.013083413590871555 0.03162634430234057 5.513224352938319e-06 5.25859433415585 -0.12880089820146057 GSPAT(ph)SPHLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSPATSPHLGR 11 0 E9PNR2;Q13671-2;Q13671 E9PNR2 RIN1 Ras and Rab interactor 1 1 GS(0.027)PAT(0.486)S(0.486)PHLGR 86.463 0.020939 0.0 20656.0 16791.0 24496.0 24972.0 31537.0 26936.0 29963.0 24439.0 24390.0 22657.0 True False 24152.652825403515 18457.899512146883 25080.077541597337 23572.899800316347 25357.55124024875 25523.428741882035 27124.687726665612 23797.502145260918 24746.657608653295 26764.534747286696 0.9024125789390767 0.6896402155474826 0.9370638338534869 0.8807513383996369 0.9474310493224404 0.9536287098907826 1.01345635120429 0.8891431280221836 0.9246063061552764 1.0 14.708034953793383 -5.340520760515342 11.086443253749547 0.9401947528277166 0.7961187134708193 0.4753266523393478 0.06180930425039505 0.5202784736311725 71.37674932466025 0.015390864762226874 0.032060630884534605 4.565404257456756e-06 5.340520760515342 -0.14407603935689728 GSPATS(ph)PHLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSPATSPHLGR 11 0 E9PNR2;Q13671-2;Q13671 E9PNR2 RIN1 Ras and Rab interactor 1 1 GSPAT(0.094)S(0.906)PHLGR 76.24 0.011807 25943000.0 13216.0 15064.0 22703.0 14881.0 22742.0 23100.0 19736.0 21205.0 23556.0 14197.0 True False 15453.207772101714 16559.454365492275 23244.325621606953 14047.265814852934 18285.86835481298 21888.59533477409 17866.46320373368 20648.391218554665 23900.461936426276 16770.803716609837 0.9214351341311584 0.9873977804111892 1.38599950332647 0.8376024221749429 1.090339417466476 1.3051607844587427 1.0653313642946463 1.231210594761446 1.4251232284565594 1.0 14.033664209190094 -6.56971027386436 9.132468531681097 1.2099535263318115 1.0437561700788778 0.18260921191622959 0.17279611806662087 0.5891747993265389 107.83907906245706 0.05648763117799164 0.05653917776105401 2.693330977215845e-07 6.56971027386436 -0.16619735625293375 GSPDGS(ph)LQTGKPSAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSPDGSLQTGKPSAPK 16 1 Q8IZL8;C9JFV4;E7EV54 Q8IZL8 PELP1 Proline-, glutamic acid- and leucine-rich protein 1 1 GS(0.405)PDGS(0.585)LQT(0.01)GKPSAPK;GS(0.051)PDGS(0.94)LQT(0.008)GKPSAPK 72.523 0.0076075000000000005 35870000.0 134595.0 187159.0 164666.0 154286.0 163596.0 120377.0 156815.0 111905.0 140692.0 116432.0 True False 157379.27512757454 205738.9086292595 168592.2619392827 145641.85562196065 131540.5381837123 114064.21820840277 141960.34795771659 108967.61232314822 142749.35433688603 137540.19992479528 1.1442420122526138 1.4958456417960289 1.2257671722991983 1.058903911013618 0.9563788496427701 0.8293154893679899 1.0321371354363174 0.7922600983765468 1.0378736864926692 1.0 17.069493822207342 -5.830601856737875 2.2092109687854964 0.9312949849780167 1.3276610401425566 0.6677166454231369 0.11012376827686869 0.15766629371962787 1.5698913526228087 0.03145313144474396 0.056203045158527254 1.4770600204541177e-06 5.830601856737875 0.39636605516453993 GSPDGS(ph)LQTGKPSAPK ddPTM_PC-9_Lapatinib_30min_R1 2 GSPDGSLQTGKPSAPK 16 1 Q8IZL8;C9JFV4;E7EV54 Q8IZL8 PELP1 Proline-, glutamic acid- and leucine-rich protein 1 1 GS(0.183)PDGS(0.817)LQTGKPSAPK;GS(0.094)PDGS(0.894)LQT(0.012)GKPSAPK 109.07 0.00034157 162329000.0 160782.0 199984.0 206162.0 184765.0 208132.0 190555.0 211979.0 202491.0 179364.0 159971.0 True False 158489.2191961921 199520.94933498077 189212.15616833346 198353.23445797138 195890.08496325582 182405.40685540086 222954.23539878687 211899.4710897394 159162.1375333462 187621.77420204107 0.8447272171380413 1.0634210777696091 1.0084765319646738 1.0571973071972665 1.0440690362106426 0.972197430874825 1.1883174879195948 1.129397011572627 0.8483137855947998 1.0 17.517467742111023 -4.757533922647735 24.64862103521939 1.0416820021208313 0.8447268742675599 0.29910173979541776 0.08658768561703233 117.62074009052458 742217.0969523786 0.021190718527287534 0.15548674875702426 1.747696744873138e-05 4.757533922647735 -0.1969551278532714 GSPHYFS(ph)PFRPY ddPTM_PC-9_AZD4547_30min_R2 1 GSPHYFSPFRPY 12 1 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 1 GSPHYFS(0.999)PFRPY 86.262 0.044487 7627900.0 18354.0 10756.0 30364.0 45603.0 35758.0 39816.0 30693.0 40341.0 24387.0 31547.0 True False 24190.190213083955 14232.666654955976 29961.353520514847 35089.93290932657 30793.61892800882 37326.29922576818 33424.61753978036 34107.22539395852 25676.047032952767 30442.549132159464 0.7946177604269504 0.46752545567613485 0.9841933206856097 1.152660795815473 1.0115322075797681 1.2261226569340324 1.097957250382513 1.1203800721775858 0.8434263149740187 1.0 14.893801548717663 -5.3997832937649655 5.248580507621924 1.0749437010441292 0.6355490723572484 0.6600687943559835 0.12230393299649857 0.1155657295331542 4.421895292532461 0.030856428704352856 0.06590412050004163 3.983058694491107e-06 5.3997832937649655 -0.43939462868688073 GSPHYFS(ph)PFRPY ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSPHYFSPFRPY 12 1 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 1 GS(0.009)PHYFS(0.991)PFRPY;GS(0.028)PHY(0.087)FS(0.885)PFRPY 93.23700000000001 0.0025604 370899000.0 31188.0 28095.0 79919.0 72492.0 87312.0 78423.0 69093.0 65921.0 64907.0 42621.0 True False 36467.5124089216 30884.085926613472 81824.57205449522 68430.50826223518 70203.84037443649 74310.35982419873 62548.01084999857 64190.64359907297 65856.14208301995 50347.849912349615 0.724311216316243 0.6134141970387904 1.6251850316735137 1.3591545295651273 1.3943761351607684 1.4759390908164969 1.2423174169083322 1.2749430951038074 1.3080229284402147 1.0 15.619642549300417 -5.249764715021298 24.967835334415774 1.3495194624333686 0.6688625947201434 0.7459912061169938 0.1552956178991198 325.6137770524067 696365.5314565618 0.03801390390943312 0.09874330313361163 5.626460638393802e-06 5.249764715021298 -0.6806568677132252 GSPLNAAPYGIESMS(ph)QDTEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSPLNAAPYGIESMSQDTEVR 21 0 B4DSN5;P18031 B4DSN5 PTPN1 Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 1 1 GSPLNAAPY(0.011)GIES(0.385)MS(0.592)QDT(0.011)EVR;GS(0.001)PLNAAPY(0.002)GIES(0.013)MS(0.984)QDT(0.001)EVR 144.51 3.2833e-11 3064100.0 18316.3 27976.0 22040.9 13134.3 22160.6 12775.3 15892.1 10065.7 12710.8 11539.8 True False 21416.887826584927 30753.27239305706 22566.438646578732 12398.427752975125 17818.389511198162 12105.340778369673 14386.685239159711 9801.486040490729 12896.671403528919 13631.874390993466 1.5710889942424202 2.255982670539838 1.655417149492538 0.9095174586678062 1.3071122136344444 0.8880173357794164 1.0553710243005867 0.7190123499792911 0.9460673590162851 1.0 13.734696326774715 -5.653598079502814 3.960273402938933 0.9758333090467138 1.9238662119012666 0.7797623356176792 0.20991098096185645 0.090956960933524 2.624358567474983 0.05654494193071362 0.1020923387328287 2.2202502135100255e-06 5.653598079502814 0.9480329028545528 GSPLVVIS(ph)QGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSPLVVISQGK 11 0 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 1 GS(0.001)PLVVIS(0.999)QGK;GS(0.001)PLVVIS(0.999)QGK 70.942 0.030966000000000004 43946000.0 14577.0 8837.7 332720.0 29104.0 148342.0 120032.0 28918.0 38476.0 98448.0 22328.0 True False 17044.598191126406 9715.048449675447 340653.306647626 27473.397236441077 119275.44998195686 113737.31061574047 26178.677691810433 37466.04576869179 99887.61575468209 26375.889651649246 0.6462188921866615 0.36833064506955804 12.915329535674086 1.041610258432485 4.52213940675547 4.312169641209757 0.9925230215001873 1.4204656701067555 3.7870804387610963 1.0 14.686932135904865 -7.250784687626252 23.367986450310244 1.8350561543851314 4.102945890519881 0.08606039128176846 3.4428935452216365 792.6921542678979 1738543.8709794297 1.3431543657786327 1.0276788694410985 5.6132619858984924e-08 7.250784687626252 2.26788973613475 GSPS(ph)PPQAEAR ddPTM_PC-9_AZD4547_30min_R2 2 GSPSPPQAEAR 11 0 M0R0S1;M0R2P6;Q8TBC3;M0R1G0;M0QZE8;M0R0K4;M0QYB1;M0R0E3;M0R0S2;M0QZF4 M0R0S1 SHKBP1 SH3KBP1-binding protein 1 1 GS(0.09)PS(0.91)PPQAEAR;GS(0.183)PS(0.817)PPQAEAR 91.307 0.008263600000000001 5604600.0 36256.0 31406.0 43470.0 61364.0 67293.0 49303.0 43067.0 43433.0 46575.0 36781.0 True False 47784.653828351926 41557.375322196676 42893.55939720656 47217.477864349166 57950.528511731645 46220.075616034985 46899.87956816601 36721.42784105007 49036.85941525296 35493.308385265074 1.346300359202062 1.1708509917167675 1.2084970758886393 1.3303205593522902 1.6327170147877679 1.3022194244147467 1.3213724417878254 1.0346014364864011 1.3815804061706023 1.0 15.115259436015354 -7.667270397254818 9.45423576378742 1.1564140882500984 1.3306264813386095 0.25486185721297394 0.1492626233318006 0.47241199496518876 42.88844640692496 0.0729505805859471 0.04200914077284718 2.1514418026741923e-08 7.667270397254818 0.1742123930885111 GSPS(ph)PPQAEAR ddPTM_PC-9_Lapatinib_30min_R1 1 GSPSPPQAEAR 11 0 M0R0S1;M0R2P6;Q8TBC3;M0R1G0;M0QZE8;M0R0K4;M0QYB1;M0R0E3;M0R0S2;M0QZF4 M0R0S1 SHKBP1 SH3KBP1-binding protein 1 1 GS(0.014)PS(0.986)PPQAEAR 87.641 0.028687999999999998 0.0 14743.0 16060.0 15124.0 15632.0 18163.0 16552.0 15071.0 13290.0 16641.0 11996.0 True False 14532.762116464919 16022.814056723466 13880.563100328292 16781.629426823318 17094.68804983192 15844.109544596531 15851.302637030643 13907.501917530315 14766.715342501373 14069.492616334752 1.0329272357407053 1.1388338224877348 0.9865716894589993 1.1927672080612033 1.2150180902746202 1.126132261955306 1.1266435165278954 0.9884863865939014 1.0495556410724536 1.0 13.780282681606733 -7.755123899492814 24.998769131590635 1.0142657533408852 1.1198463402159977 0.3503075618262994 0.0650014516281289 170.3164165193708 674175.9048955216 0.03281460686263791 0.018353037172619928 1.7574221690005265e-08 7.755123899492814 0.10558058687511251 GSPSQEWVIHAS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 1 GSPSQEWVIHASPVK 15 0 Q5T7B8-4;Q5T7B8-2;Q5T7B8 Q5T7B8-4 KIF24 Kinesin-like protein KIF24 1 GSPSQEWVIHAS(1)PVK 64.298 0.020533000000000003 3181600.0 14599.0 16688.0 17890.0 18932.0 17290.0 16892.0 20535.0 18099.0 18317.0 16308.0 True False 19241.178321935968 22082.0696483735 17652.766910881648 14567.519896484238 14889.581947124349 15835.740569662346 22362.57521843382 15302.215423644813 19285.199225103355 15737.06188376887 1.2226664967099878 1.4031888424578696 1.1217320641719422 0.925682316310207 0.9461475119749889 1.0062704643739917 1.4210133621891943 0.9723680021508617 1.2254637725606212 1.0 13.941878593750312 -5.394751477201127 5.6703248513151685 1.0729730915864282 1.3101661892470242 0.2928659826596659 0.14791132380867042 0.2787713524632745 11.568926614044052 0.039940226392709686 0.08477815614109227 4.029475530415432e-06 5.394751477201127 0.23719309766059604 GSPSSYNSSSS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 GSPSSYNSSSSSPR 14 0 Q9H201;I6L9I8 Q9H201 EPN3 Epsin-3 1 GSPSSYNS(0.007)S(0.025)S(0.165)S(0.401)S(0.401)PR 99.991 0.0020684 3631500.0 5499.4 6888.9 10675.0 13596.0 12261.0 10035.0 8545.0 11395.0 9005.8 9111.5 True False 7248.094805373972 9115.60220521813 10533.442525078912 10461.652256106043 10558.771790265571 9407.509863637315 9305.488446141564 9634.164581050487 9481.828202294913 8792.509158324754 0.8243488491008816 1.0367463986759082 1.1980018826714376 1.189836947306554 1.2008826604711031 1.069945984046008 1.0583427641165573 1.0957241451297044 1.0783984448077044 1.0 13.102059217232354 -4.82009383053337 3.2988760978974656 1.1175838867916985 0.7970155348744136 0.6450558586742854 0.06383976380781509 0.18559995922941658 3.2674938200290966 0.017230857904987913 0.14478585726259424 1.5132342746326472e-05 4.82009383053337 -0.32056835191728494 GSPSSYNSSSS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSPSSYNSSSSSPR 14 0 Q9H201;I6L9I8 Q9H201 EPN3 Epsin-3 1 GSPSSYNS(0.001)S(0.002)S(0.021)S(0.735)S(0.241)PR 82.48299999999999 0.009190299999999998 2741800.0 4428.6 4643.4 7802.9 6101.0 10117.0 7311.0 7030.3 7298.1 7705.7 6772.1 True False 5178.274511162953 5104.366064838477 7988.950728663041 5759.180749708874 8134.646475492169 6927.598289720066 6364.339089035717 7106.532607976129 7818.381284747832 7999.8281220859 0.6472982209288709 0.6380594666460845 0.9986402966092699 0.7199130608580134 1.016852656250709 0.8659683913201053 0.7955594785174284 0.8883356616570844 0.9773186580300232 1.0 12.965753288402324 -5.247045165370258 24.82144061865246 0.8955140649888043 0.6426787821558084 0.5676149858798258 0.09206582981158888 515.028106169123 888112.5698944144 0.022330971418223433 0.058484953065766766 5.66180404851547e-06 5.247045165370258 -0.25283528283299583 GSPSSYNSSSSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 GSPSSYNSSSSSPR 14 0 Q9H201;I6L9I8 Q9H201 EPN3 Epsin-3 1 GSPSSYNSS(0.001)S(0.004)S(0.385)S(0.611)PR;GSPSSYNSSSS(0.05)S(0.95)PR 159.58 0.00045516 7382300.0 11020.4 10704.0 20649.7 25337.0 21976.0 21276.0 14470.0 21699.0 13738.099999999999 18843.3 True False 14524.657961440033 14163.8586718714 20375.871485725696 19495.94610274779 18925.01173337217 19945.60835662658 15757.801967895655 18345.91814341505 14464.267919112976 18183.601802454137 0.7987778284651901 0.7789358140233682 1.1205630054533904 1.0721718565194565 1.0407735463508647 1.0969008545894705 0.8665940961030567 1.0089265230686588 0.7954567019368416 1.0 14.150350375993671 -5.241788295737932 24.35452124556388 1.0031973783070958 0.7888567383075352 0.4401600111980437 0.09527908272435745 547.4885345027994 678524.6203243162 0.02491984385335816 0.06569598191153754 5.730753182594673e-06 5.241788295737932 -0.21434063999956054 GSPSSYNSSSSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSPSSYNSSSSSPR 14 0 Q9H201;I6L9I8 Q9H201 EPN3 Epsin-3 1 GSPSSYNSSS(0.001)S(0.083)S(0.916)PR;GSPSSYNSS(0.001)S(0.001)S(0.011)S(0.986)PR 138.31 7.5743e-05 6024800.0 14811.0 20917.0 24992.0 25351.0 30102.0 23154.0 26834.0 25836.0 25015.0 22795.0 True False 17318.20976941573 22993.50152436284 25587.90406268781 23930.665659050937 24203.729189015055 21939.763479712543 24292.08925866386 25157.832375504757 25380.79705126946 26927.553054879296 0.6431408651993226 0.853902375663369 0.950249880133511 0.8887055429908318 0.8988462167240747 0.8147700400032092 0.9021276166146894 0.9342784442475042 0.9425586127169634 1.0 14.716795515590926 -4.7801774122329785 3.2485208077796828 0.9083011044305169 0.6052483390752063 0.7569792289726569 0.04626372196175165 0.16425979894645057 2.6701711618452886 0.011879194442581195 0.12746771109089858 1.6589090934173657e-05 4.7801774122329785 -0.30305276535531067 GSPSSYNSSSSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 GSPSSYNSSSSSPR 14 0 Q9H201;I6L9I8 Q9H201 EPN3 Epsin-3 1 GSPSSYNS(0.001)S(0.006)S(0.036)S(0.227)S(0.73)PR;GSPSSYNSSS(0.004)S(0.132)S(0.864)PR;GSPSSYNSS(0.001)S(0.011)S(0.233)S(0.755)PR 115.09 0.00016404 10473400.0 21304.800000000003 19459.7 25422.7 21726.7 24887.1 26884.199999999997 22414.5 20394.3 29824.0 19763.5 True False 21000.989645178186 19414.6422602504 23332.543740459918 23324.553996146533 23423.289707921158 25734.42543613113 23575.013135009194 21341.89363105254 26464.90705935706 23179.59464179158 0.9060119458394028 0.8375747100101064 1.006598437161303 1.0062537484626068 1.0105133445987968 1.110218959124217 1.017058904580872 0.9207190186395338 1.1417329538473566 1.0 14.500567716670774 -5.338570132635776 5.144400489486922 1.0264476745892233 0.8722148069233634 0.5206147055190917 0.05957424221151094 0.1541867081739423 7.261782901552049 0.015356598047019665 0.033420318604698705 4.58595582886129e-06 5.338570132635776 -0.15423286766585986 GSPSVAAS(ph)SPPAIPK ddPTM_PC-9_AZD4547_30min_R2 1 GSPSVAASSPPAIPK 15 0 Q92610;H0YM74 Q92610 ZNF592 Zinc finger protein 592 1 GSPS(0.002)VAAS(0.586)S(0.411)PPAIPK 140.31 6.9697e-05 12975000.0 109590.0 89972.0 136110.0 165120.0 171690.0 142280.0 112550.0 144620.0 123040.0 149360.0 True False 144437.34038639374 119053.68950164551 134305.09246730592 127054.13507856944 147853.8070851232 133383.20910795385 122566.73196175917 122272.30203699152 129543.64320886169 144130.95186164594 1.0021257649435489 0.8260105686107411 0.931826861146577 0.881518739989528 1.0258296720821694 0.9254307099559778 0.8503845314184376 0.8483417368558215 0.8987912834518231 1.0 17.13702065937533 -9.561991802270423 10.092179567762614 1.000003722379534 0.9076506595710916 0.15987565428613648 0.061657012112933084 0.0 0.0 0.06010221807880287 0.01457692902781245 2.741625922287902e-10 9.561991802270423 -0.09235306280844235 GSPSVAAS(ph)SPPAIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSPSVAASSPPAIPK 15 0 Q92610;H0YM74 Q92610 ZNF592 Zinc finger protein 592 1 GSPS(0.002)VAAS(0.591)S(0.407)PPAIPK 151.74 0.00014648 4596300.0 27203.0 20740.0 30277.0 34457.0 30713.0 30073.0 31716.0 31385.0 30607.0 25445.0 True False 31807.930616259295 22798.93013411508 30998.918506161932 32526.486001101242 24695.00812511526 28495.918939509174 28711.63087604468 30561.177005156245 31054.569472244842 30057.97707749084 1.058219271851096 0.7584984869520126 1.031304216722413 1.0821249186945108 0.8215791788466136 0.9480318274927615 0.9552083562385048 1.0167409778232293 1.0331556708618395 1.0 14.87546029770336 -7.736042613966749 4.248979560487941 1.019937535505339 0.9456620196951796 0.09133380576552297 0.0946768543841506 0.4945180298195164 20.047238400820383 0.05028825462000667 0.025803646421591088 1.836358146851152e-08 7.736042613966749 -0.07427551581015945 GSPSVAAS(ph)SPPAIPK ddPTM_PC-9_Lapatinib_30min_R1 1 GSPSVAASSPPAIPK 15 0 Q92610;H0YM74 Q92610 ZNF592 Zinc finger protein 592 1 GSPS(0.001)VAAS(0.654)S(0.345)PPAIPK 230.69 7.5612e-25 10117000.0 65276.0 59066.0 65793.0 63075.0 69678.0 62457.0 50142.0 47991.0 63841.0 48876.0 True False 64345.15226984763 58929.236306004204 60383.75350832443 67713.74591203181 65579.67703221872 59785.85970437807 52738.10741330976 50220.837059759026 56650.55430446673 57324.15147682371 1.1224789309940773 1.0280001498117148 1.0533736994386689 1.1812428822327816 1.1440147885788199 1.0429436487786414 0.9199980471517646 0.8760851362983267 0.9882493302560384 1.0 15.806855474462564 -7.093611414178054 3.7629253032461127 0.9365587177708774 1.1024322699270004 0.6727986808231587 0.052194426976456716 0.14757731997199983 3.831404466125158 0.02211764042573913 0.017074715472362695 8.060993775879432e-08 7.093611414178054 0.16587355215612298 GSPSVAASS(ph)PPAIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSPSVAASSPPAIPK 15 0 Q92610;H0YM74 Q92610 ZNF592 Zinc finger protein 592 1 GSPSVAAS(0.262)S(0.738)PPAIPK 144.8 0.00010797 3977600.0 18271.0 18023.0 22808.0 23206.0 27970.0 21746.0 19942.0 23158.0 22047.0 20270.0 True False 21363.919431300714 19812.204330142544 23351.82921982167 21905.8430548671 22489.479284325 20605.60147835488 18052.949392422845 22550.127037929233 22369.3956661738 23944.790542768293 0.8922157574584823 0.8274118871391065 0.9752363119699242 0.9148479714508512 0.9392222180501462 0.8605463239091937 0.7539405851213479 0.9417550342589959 0.934207197436927 1.0 14.54742419519306 -8.409423934315354 2.10675320710092 0.9942743343634696 0.8850881265783702 0.25943650161998444 0.0598676636605991 0.43635467608915224 4.01273331810999 0.05985480579910418 0.016823761302972546 3.895615325397018e-09 8.409423934315354 -0.10918620778509935 GSPT(ph)GGAQLLKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSPTGGAQLLKR 12 1 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 GS(0.476)PT(0.524)GGAQLLKR 71.221 0.023698 7100600.0 32690.0 16650.0 26592.0 32728.0 38678.0 42219.0 38277.0 32314.0 37457.0 30081.0 True False 38223.77134306937 18302.90196398342 27226.0541307216 30894.356265607632 31099.32355234618 40004.961317698166 34651.12545851817 31465.791739513104 38004.737763318015 35534.44717893503 1.0756821725857209 0.5150749038480457 0.7661876374106453 0.8694199211834633 0.8751880505061577 1.1258078989171183 0.9751418189800769 0.8855010908447778 1.0695181937668468 1.0 15.116930634542776 -6.255968672949349 1.969180208703557 0.9991157442565872 0.7662277996449145 0.30406577807487833 0.14245234238872506 0.38570082770668324 2.93867258777153 0.04775160340898851 0.06255262230211796 5.546657213282467e-07 6.255968672949349 -0.23288794461167273 GSPT(ph)SAYPERR ddPTM_PC-9_Lapatinib_30min_R1 1 GSPTSAYPERR 11 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 GS(0.104)PT(0.737)S(0.152)AY(0.007)PERR 89.35600000000001 0.031800999999999996 6907900.0 28770.0 21319.0 25986.0 21703.0 24765.0 21575.0 17174.0 19045.0 20965.0 18399.0 True False 28359.73452422815 21269.637165335447 23849.531388860803 23299.111019085653 23308.371389863314 20652.287543781425 18063.185686972625 19929.90022719073 18603.700928762784 21579.242634873557 1.3142136174138406 0.9856526257766912 1.1052070636769384 1.0797001272617728 1.080129260523507 0.9570441323276977 0.837063005064935 0.9235681049798581 0.8621109296346624 1.0 14.397356611099841 -6.807548208492389 2.737522290509586 0.8982657358341275 1.1080538843968775 0.5707259833363094 0.08640881261402023 0.19649935982725225 3.008648322521766 0.031207103273239552 0.028174429202979287 1.5575851268127325e-07 6.807548208492389 0.20978814856274997 GSPTDAEGS(ph)PGLSR ddPTM_PC-9_Lapatinib_30min_R1 1 GSPTDAEGSPGLSR 14 0 Q8TER5-4;Q8TER5-3;Q8TER5;G3V485;G3V3N2;G3V5C1 Q8TER5-4 ARHGEF40 Rho guanine nucleotide exchange factor 40 1 GSPT(0.028)DAEGS(0.968)PGLS(0.004)R 99.238 0.010012 0.0 19105.0 18434.0 18840.0 14613.0 16690.0 16509.0 11730.0 13587.0 13840.0 9655.7 True False 18832.559196572096 18391.317205581592 17291.047924503106 15687.688767538983 15708.327013802491 15802.948554358645 12337.322004669202 14218.301621782113 12281.193458338987 11324.674879588481 1.6629668751476279 1.6240039913843336 1.5268471817825318 1.3852661497430154 1.387088563762221 1.395443906547973 1.0894195317612083 1.2555152154883569 1.0844632264432181 1.0 13.467182012042743 -5.83346670983729 0.2750742887508638 0.9684640924252368 1.9780931701377737 0.9119509573927387 0.06487709366262959 1.2982386996112059 0.1317419797252027 0.08999489821522806 0.4307023464442632 1.4673485599006196e-06 5.83346670983729 1.009629077712537 GSPTTGFIEQKGS(ph)PTSAYPER ddPTM_PC-9_AZD4547_30min_R2 2 GSPTTGFIEQKGSPTSAYPER 21 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 GSPT(0.003)T(0.01)GFIEQKGS(0.658)PT(0.239)S(0.089)AY(0.001)PER;GSPT(0.001)T(0.001)GFIEQKGS(0.647)PT(0.251)S(0.099)AY(0.002)PER 61.091 0.004278100000000001 24645000.0 47881.0 24396.0 55550.0 98342.0 78183.0 48832.0 42462.0 57915.0 47526.0 72715.0 True False 63106.16201333077 32281.529910218094 54813.37070427481 75670.77126875416 67328.63998681444 45778.527320492045 46241.03574020631 48965.56750430354 50038.127333747994 70169.26998272339 0.8993418633095136 0.4600522410759901 0.7811591985746836 1.0784032851900172 0.959517464032213 0.6524013621883672 0.6589926865648092 0.6978206772902086 0.7131059984815012 1.0 16.09855173272932 -11.975532099037386 2.078606872317486 3.056379452886252 0.7644332730005506 0.1493943486954994 0.1668842474346871 6942160.1907358 559177.3908092182 67179023.14077559 0.046269095379253077 1.0579567187160561e-12 11.975532099037386 -2.2919461798857013 GSPTTGFIEQKGS(ph)PTSAYPER ddPTM_PC-9_Lapatinib_30min_R1 2 GSPTTGFIEQKGSPTSAYPER 21 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 GSPTTGFIEQKGS(0.746)PT(0.2)S(0.054)AYPER;GSPTTGFIEQKGS(0.832)PT(0.135)S(0.033)AYPER 111.84 1.0365e-05 18669800.0 90945.0 42704.0 57232.0 50243.0 42861.0 53655.0 43084.0 30521.0 66096.0 39367.0 True False 89648.10762272944 42605.121511725956 52526.60588190878 53938.03782573465 40340.00024796816 51360.300725913956 45314.678708368934 31939.117082388468 58651.57245826402 46171.53349676978 1.9416315819140237 0.9227573417007401 1.1376404876304056 1.168209798132614 0.8736985149256608 1.1123802229680586 0.9814419248504971 0.6917491073720341 1.2702972592921862 1.0 15.494716029013723 -4.758021220969516 24.996785778100975 1.013738840630725 1.9416328792943176 0.7563167466948776 0.15734152378748778 45.49103202820502 332620.6712478239 0.03787437313114778 0.26834280368302127 1.745736848743028e-05 4.758021220969516 0.9278940386635925 GSPTTGFIEQKGSPT(ph)SAYPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSPTTGFIEQKGSPTSAYPER 21 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 GSPT(0.006)T(0.022)GFIEQKGS(0.229)PT(0.583)S(0.15)AY(0.01)PER 62.617 0.0049458 9681600.0 18447.0 14198.0 13555.0 24446.0 35390.0 28419.0 25144.0 33213.0 27136.0 21320.0 True False 21569.712755142256 15607.483608686878 13878.202607623762 23076.36987500135 28455.583549240688 26928.657611209746 22762.1782932043 32341.193942082336 27532.81266373167 25185.14723097286 0.8564457677108864 0.6197098418981125 0.5510471104396109 0.9162690082121846 1.1298557553892647 1.0692277223653752 0.9037937354287618 1.284137577020353 1.0932162679546156 1.0 14.620285544485336 -5.967910122111953 4.349584440033021 1.0818192688745631 0.6723531945054988 0.7078619696951667 0.1160397891859941 0.10917238105949298 4.762380637178017 0.034322286468833174 0.05069248785128042 1.0766880127580785e-06 5.967910122111953 -0.40946607436906435 GSPVS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 GSPVSPR 7 0 Q14676;Q14676-3 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 GS(0.004)PVS(0.996)PR 87.696 0.017768 22658000.0 91807.0 97549.0 135040.0 176740.0 147580.0 140130.0 106740.0 181750.0 121280.0 156230.0 True False 120999.71629577172 129079.80657533475 133249.28136643145 135995.32360577982 127091.06441622949 131367.64894783217 116239.65321722072 153664.71369951055 127690.61320197278 150760.4352527114 0.8025959602262129 0.856191522390907 0.8838478155298041 0.9020624235915633 0.8430001160662195 0.871366872400095 0.7710222713431053 1.0192641951579064 0.8469769471541525 1.0 17.201898339688505 -8.853008495417727 0.5469477828946883 1.0032977665623912 0.8530200062645228 0.31826132900968795 0.06137998158435076 1.7039226366425948 1.0292436753012575 0.07622043312064321 0.028577106481756053 1.4027862637991816e-09 8.853008495417727 -0.15027776029786843 GSPVS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSPVSPR 7 0 Q14676;Q14676-3 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 GS(0.017)PVS(0.983)PR 79.71300000000001 0.026466000000000003 18839000.0 76241.0 71275.0 95938.0 98792.0 117440.0 118020.0 82776.0 99015.0 80718.0 72476.0 True False 89147.09547161046 78350.71095993494 98225.52576689103 93257.0045279854 94428.47505009385 111830.82343766415 74934.85803365718 96415.96116506454 81898.34804654676 85615.32508029952 1.041251614567818 0.9151482037409655 1.147289059228173 1.089255976549977 1.1029389301684995 1.3062010023646682 0.8752505227700179 1.126153069846257 0.9565851437196954 1.0 16.385581440643705 GSPVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 GSPVSPR 7 0 Q14676;Q14676-3 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 GSPVS(1)PR 75.043 0.033296 22199000.0 146770.0 134870.0 168790.0 138400.0 124270.0 144090.0 111210.0 115970.0 154870.0 107520.0 True False 144677.03288567823 134557.716801388 154912.73774824198 148578.3976888655 116960.68292422032 137927.60659019538 116967.90964529077 121358.38956929972 137426.909746601 126104.68873860531 1.1472771895545486 1.0670318300400743 1.2284455026834975 1.1782146974474879 0.9274887721792879 1.0937547839802932 0.9275460794938909 0.9623622308037736 1.0897842984368713 1.0 16.944262392404113 -6.250338603368467 24.96280575281467 0.9993235788885327 1.154170364872434 0.5758285486378864 0.06520338625186703 532.8281593635753 1198193.8340417265 0.019186912617300014 0.024533774025014433 5.619030592991766e-07 6.250338603368467 0.15484678598390123 GSQEDDPAATQRPPS(ph)NGGAK ddPTM_PC-9_AZD4547_30min_R2 1 GSQEDDPAATQRPPSNGGAK 20 1 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 GSQEDDPAAT(0.03)QRPPS(0.97)NGGAK 57.238 0.0091322 7717500.0 23971.0 22381.0 25039.0 21431.0 23269.0 28431.0 28823.0 34829.0 26593.0 21501.0 True False 31593.279372225956 29615.220565690764 24706.966499808022 16490.41405564937 20038.50100217679 26653.20507554286 31388.191162450334 29446.97834079922 27998.651689314498 20748.25653439507 1.5226956211888325 1.4273594755586636 1.1907972344013806 0.7947855294883531 0.9657920398737264 1.2845997460730718 1.5128110215148485 1.4192507352116064 1.34944599527677 1.0 14.34070249216041 -6.992788695786872 24.856712168081884 1.361513217365168 1.168381175511517 0.06635923120229192 0.23038860677252487 379.47438741482335 1308005.1646097465 0.08893330585564131 0.07827337138654371 1.0167432648435699e-07 6.992788695786872 -0.19313204185365107 GSQEDDPAATQRPPS(ph)NGGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSQEDDPAATQRPPSNGGAK 20 1 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 GSQEDDPAAT(0.008)QRPPS(0.992)NGGAK 54.071999999999996 0.012031 7402300.0 14164.0 24636.0 15877.0 18346.0 23628.0 13550.0 15407.0 11890.0 16585.0 12905.0 True False 16561.685448248227 27081.69926634809 16255.567893857797 17318.133098534516 18998.263015017215 12839.414146588271 13947.53742297958 11577.90009849635 16827.524249262606 15244.574344076218 1.0863986802415257 1.7764811699627137 1.0663182537578975 1.1360194589666617 1.2462311236915327 0.8422284451371022 0.9149181281272937 0.7594767710254452 1.1038369369625263 1.0 13.89600824782013 -6.073228685896849 0.9462235541170692 0.9134327688226427 1.4037198510923 0.37715421499012847 0.2099696510578245 0.5696593195865268 1.050626048233955 0.09133990321727659 0.1834579497656013 8.448338649129536e-07 6.073228685896849 0.4902870822696572 GSQEDDPAATQRPPS(ph)NGGAK ddPTM_PC-9_Lapatinib_30min_R1 2 GSQEDDPAATQRPPSNGGAK 20 1 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 GSQEDDPAAT(0.007)QRPPS(0.993)NGGAK;GSQEDDPAAT(0.09)QRPPS(0.91)NGGAK 57.662 0.008772499999999999 14853000.0 27668.0 44462.0 48673.0 46331.0 55646.0 58086.0 54323.0 62912.0 54809.0 47720.0 True False 27273.449246310207 44359.05097073712 44671.29382321333 49738.336295685265 52373.01168424526 55601.79718507943 57135.5791355196 65835.12119154754 48635.833255643185 55968.33841709692 0.48730139249549087 0.7925740199781693 0.7981529394406208 0.888687027387103 0.9357614173560426 0.9934509181014828 1.020855375582601 1.176292222594133 0.8689883357478084 1.0 15.772323297320584 -4.413268966843084 0.5557423379994074 1.0285127764174709 2.437406974872401e-15 0.7876123628931897 0.0803706412915634 2.5313906573942506 0.44205697701436164 0.04215411581163512 1.835921868518425 3.8612776670884746e-05 4.413268966843084 -1.0285127764174684 down GSQEERR ddPTM_PC-9_AZD4547_30min_R2 1 GSQEERR 7 1 F8WAQ2;C9J8X3;B8ZZ94;C9JN04;C9J6B4;B4DIZ1;Q8TAM6;Q8TAM6-2 F8WAQ2 ERMN Ermin 0 71.715 0.025756 709800.0 0.0 513.51 0.0 471.44 562.79 0.0 0.0 0.0 403.59 0.0 False True 0.0 679.4920652646374 0.0 362.7567916753923 484.6563229625282 0.0 0.0 0.0 424.9229434546852 0.0 0.0 GSQITQQS(ph)TNQSR ddPTM_PC-9_Lapatinib_30min_R1 2 GSQITQQSTNQSR 13 0 P50750;P50750-2 P50750 CDK9 Cyclin-dependent kinase 9 1 GSQIT(0.001)QQS(0.499)T(0.499)NQS(0.002)R;GSQIT(0.018)QQS(0.764)T(0.218)NQSR 119.65 0.0010395 0.0 6987.1 8078.2 7862.200000000001 8021.0 7889.1 8709.900000000001 8574.9 8782.3 9392.4 6202.9 True False 6887.462672722783 8059.495424223133 7215.800264969652 8610.891097271617 7425.078648567365 8337.397880768569 9018.866364692063 9190.35771936241 8334.529005643286 7275.063000155287 0.9467220658536936 1.1078248290153778 0.9918539901050519 1.183617392328811 1.0206205291155384 1.1460241486005833 1.2396959812581079 1.2632684719247436 1.145629804919268 1.0 12.8287440261013 -6.918566923866631 5.115148356542444 1.1853282770874003 1.0580750736231044 0.2503573677805071 0.09027421657635398 0.25090049411181214 11.454010285719146 0.031016618193253104 0.027181698619265577 1.2062381951045457e-07 6.918566923866631 -0.12725320346429592 GSQITQQST(ph)NQSR ddPTM_PC-9_AZD4547_30min_R2 2 GSQITQQSTNQSR 13 0 P50750;P50750-2 P50750 CDK9 Cyclin-dependent kinase 9 1 GSQITQQS(0.066)T(0.933)NQSR;GSQIT(0.004)QQS(0.009)T(0.977)NQS(0.009)R 116.78 0.00067959 0.0 5265.9 4541.01 6774.799999999999 7958.5 7771.1 8378.6 6730.799999999999 8715.1 7028.6 7239.7 True False 6940.346662475686 6008.802678209522 6684.96172542432 6123.790782599292 6692.216903950146 7854.68481748597 7329.828160712649 7368.38154807486 7400.117446828707 6986.240306593182 0.9934308523464066 0.860091038170958 0.9568754340035321 0.8765502636403784 0.9579139294184377 1.1243078498277828 1.049180652116305 1.0546991263843353 1.0592417555183342 1.0 12.770300552812508 -6.596316120501666 6.116330921869651 1.0597656102327944 0.9194736074864267 0.6766198940489878 0.04492195185258809 0.10943404915521635 6.986469242196454 0.013889386271662045 0.013901037322695061 2.533283996110186e-07 6.596316120501666 -0.14029200274636766 GSQITQQST(ph)NQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSQITQQSTNQSR 13 0 P50750;P50750-2 P50750 CDK9 Cyclin-dependent kinase 9 1 GSQIT(0.002)QQS(0.362)T(0.635)NQSR 95.236 0.009312299999999999 0.0 2733.2 2767.4 3727.2 4014.6 4493.9 2689.9 2069.7 2300.4 3626.1 1238.4 True False 3195.876776839315 3042.129182890554 3816.0705834847117 3789.674977508812 3613.352554731073 2548.836908701682 1873.6430326696188 2240.0169374752727 3679.1248525927695 1462.9121168309944 2.184599293471109 2.0795023486991884 2.608543971698862 2.5905007784870384 2.4699724017314377 1.7423035050273914 1.280762535980878 1.5312040359113759 2.514932243888036 1.0 10.514627388095846 -6.820272824276284 5.20213996953166 1.6141663548346643 2.393665777433638 0.49298344260590565 0.39317354606020055 0.1819723002847066 9.916705606741143 0.14094653503900534 0.12584925533187175 1.512610726168331e-07 6.820272824276284 0.7794994225989735 GSQPPPAAES(ph)QSSLRR ddPTM_PC-9_Lapatinib_30min_R1 1 GSQPPPAAESQSSLRR 16 1 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;E9PJP4;E9PQN0;E9PRG1;E9PIG0;E9PQD2;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 GSQPPPAAES(0.534)QS(0.127)S(0.339)LRR 75.319 0.0056942 3796400.0 17294.0 25097.0 23098.0 25474.0 24518.0 18543.0 13509.0 18724.0 23531.0 15143.0 True False 17047.384388668823 25038.889438455073 21198.971600858426 27347.442938772856 23075.899444242637 17749.959115844238 14208.429919955355 19593.9853953226 20880.690987584876 17760.447373220835 0.9598510685250436 1.4098118652241078 1.1936057214877476 1.5397947114782295 1.2992859334746505 0.9994094598432013 0.8000040551556599 1.1032371529596923 1.1756849672080185 1.0 14.11638030217205 -6.760572730575442 24.94420432746359 1.0086404729729062 1.2972367153448026 0.38565433214374234 0.1663194603550062 22.941806080263373 660327.3793600154 0.05693797424101825 0.053812906294799484 1.7355105954569144e-07 6.760572730575442 0.2885962423718964 GSQPPPAAESQS(ph)SLRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSQPPPAAESQSSLRR 16 1 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;E9PJP4;E9PQN0;E9PRG1;E9PIG0;E9PQD2;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 GSQPPPAAES(0.237)QS(0.721)S(0.043)LRR 120.74 3.9812e-05 5044100.0 19648.0 31542.0 27401.0 22047.0 31561.0 20122.0 18123.0 18345.0 16588.0 11604.0 True False 22974.018334310997 34673.281306184086 28054.343758871193 20811.778067338397 25376.8486125342 19066.766897243477 16406.2582408424 17863.463188134185 16830.56811858716 13707.713342786543 1.6759920316250771 2.5294723079710684 2.046610040443713 1.518253084734242 1.851282411437962 1.3909516795722203 1.1968632426557066 1.3031687154104763 1.2278173388739537 1.0 13.742700307036795 -6.479197148150586 0.705757132692437 1.1308951654943347 2.1659914816640318 0.688141983317418 0.2450213786608824 0.41843833392440266 0.46291351536358966 0.1619895789255633 0.22530473338670562 3.317438281250163e-07 6.479197148150586 1.035096316169697 GSQPPPAAESQS(ph)SLRR ddPTM_PC-9_Lapatinib_30min_R1 1 GSQPPPAAESQSSLRR 16 1 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;E9PJP4;E9PQN0;E9PRG1;E9PIG0;E9PQD2;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 GSQPPPAAES(0.035)QS(0.6)S(0.364)LRR 95.662 0.0035725 1655100.0 6833.4 7509.3 6822.1 6528.9 7104.6 5748.6 6369.1 5367.4 5975.0 5396.9 True False 6735.954462907915 7491.912677220015 6261.213272067547 7009.057085771928 6686.721396181024 5502.7457786411105 6698.860833754356 5616.788998657049 5302.032580460652 6329.746974082782 1.0641743643921873 1.1836038166921574 0.9891727580429602 1.1073202632696992 1.056396317824374 0.8693468792942535 1.058314157135019 0.8873639059594408 0.8376373656277071 1.0 12.627932115037355 -6.6389394719808275 5.926838424221132 0.9320213566694638 1.0854649782181955 0.5049548380184243 0.0744212083285944 0.17986464835843993 8.654402424326518 0.024531760294490203 0.024464915296223497 2.2964686867511545e-07 6.6389394719808275 0.1534436215487317 GSQPPPAAESQSS(ph)LRR ddPTM_PC-9_AZD4547_30min_R2 1 GSQPPPAAESQSSLRR 16 1 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;E9PJP4;E9PQN0;E9PRG1;E9PIG0;E9PQD2;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 GSQPPPAAES(0.015)QS(0.119)S(0.866)LRR 133.52 1.4497e-05 0.0 3635.7 4358.1 6611.3 3569.4 7110.1 7992.3 6514.4 8493.8 6751.6 5687.4 True False 4791.776972742142 5766.770597709524 6523.62984225332 2746.5299766802673 6122.985344259627 7492.540217553417 7094.168979935002 7181.278378106763 7108.475792335415 5488.285857109832 0.8730917261779662 1.050741661030452 1.1886461478317945 0.5004349350940347 1.1156462151707294 1.3651876765579114 1.2926019461513323 1.3084738231708055 1.2952087368274918 1.0 12.422139910832895 -6.518609448775643 24.7148788605871 1.2703515152324596 0.918388277280883 0.43278156973987747 0.18760160483515062 148.29155868138395 858464.8355978846 0.060467782494709646 0.06191971622130115 3.0296366873206996e-07 6.518609448775643 -0.3519632379515766 GSQPPPAAESQSS(ph)LRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSQPPPAAESQSSLRR 16 1 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;E9PJP4;E9PQN0;E9PRG1;E9PIG0;E9PQD2;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 GSQPPPAAES(0.173)QS(0.173)S(0.654)LRR 130.02 7.0162e-06 5017000.0 27852.0 40155.0 40135.0 25729.0 45534.0 23878.0 26471.0 20380.0 24392.0 19654.0 True False 32566.793497924984 44141.32302485011 41091.97061283509 24287.487544543455 36611.93956855396 22625.79564518339 23963.475246556252 19845.046594394913 24748.686854869655 23217.114619021606 1.4027063238617625 1.901240690291698 1.769899976251517 1.0461027540711239 1.5769375380762463 0.9745309017273941 1.032147001889854 0.8547593841887664 1.0659673805716254 1.0 14.50290106736508 -6.302434262108284 0.8994758763062826 0.9561544356024834 1.7113793212831556 0.6070318523000704 0.2207953365527809 0.38625142530227013 0.671750052307257 0.1101643005348762 0.1706125059994697 4.983858894828535e-07 6.302434262108284 0.7552248856806723 GSQPPPAAESQSS(ph)LRR ddPTM_PC-9_Lapatinib_30min_R1 1 GSQPPPAAESQSSLRR 16 1 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;E9PJP4;E9PQN0;E9PRG1;E9PIG0;E9PQD2;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 GSQPPPAAES(0.01)QS(0.217)S(0.773)LRR 168.62 1.7504e-05 6095400.0 26000.0 31992.0 28976.0 29127.0 30937.0 21774.0 20060.0 23284.0 25153.0 23446.0 True False 25629.235232183957 31917.924489582612 26593.705130594582 31269.096744823626 29117.34648448221 20842.7767776731 21098.608645666176 24365.859642421045 22320.00426716767 27498.60986016876 0.9320193043397238 1.1607104741616467 0.9670927099887724 1.137115545252211 1.0588661256894356 0.7579574707106735 0.7672609180228827 0.8860760513466738 0.8116775495439787 1.0 14.747071067330996 -6.749671462048638 24.941538357049104 0.8326408131987196 1.0573517903126106 0.5631156216779469 0.09058616586581786 142.12148377684787 301219.1173449402 0.028329992238233473 0.0281092315210128 1.7796251635226801e-07 6.749671462048638 0.224710977113891 GSRPIDTSR ddPTM_PC-9_Lapatinib_30min_R1 1 GSRPIDTSR 9 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73;H7C044 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 0 74.92 0.034645 2573800.0 10030.0 10736.0 12305.0 10109.0 12475.0 15418.0 11676.0 9490.8 14011.0 8832.1 False True 9886.970360723271 10711.14145161787 11293.330398673603 10852.449582635427 11741.24502679366 14758.608081113434 12280.526148893236 9931.777215868817 12432.93363762915 10358.7167169665 0.9544589963088229 1.0340220458074825 1.0902248519043196 1.0476635165493273 1.1334652107594294 1.4247525523060562 1.1855258218210574 0.9587845181248753 1.2002387918636 1.0 13.338557666286016 -6.2905366161262215 4.463698903880305 1.1652003961318789 1.034825924162373 0.18236891565728253 0.12204535949070681 0.3705810887964129 18.218391310826107 0.04043859982663135 0.04797383104634422 5.122280815997933e-07 6.2905366161262215 -0.1303744719695059 GSRPPLILQSQSLPCS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 2 GSRPPLILQSQSLPCSSPR 19 1 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 GSRPPLILQSQS(0.004)LPCS(0.618)S(0.377)PR;GSRPPLILQSQS(0.003)LPCS(0.615)S(0.382)PR 94.456 0.00035962 298260000.0 205830.0 231870.0 251430.0 261230.0 226530.0 243280.0 218498.0 301190.0 235560.0 231012.0 True False 271279.6584700369 306817.44303501665 248095.8739185566 201007.45946326762 195080.21969242799 228067.6631415735 237943.89871328723 254648.006157665 248011.22069472898 222924.34019458067 1.2169135870638847 1.376329936727454 1.1129151428776456 0.9016846670391273 0.8750960954831186 1.0230720563869493 1.0673751395006783 1.1423068738720688 1.112535403169753 1.0 17.76619462159028 -5.453560050244591 5.017114554869909 1.01862647242437 1.2916429894654857 0.6208409235490375 0.08622457468618822 0.15036511788228088 7.154056249136238 0.025808844141801915 0.05446092752876915 3.5191675934934126e-06 5.453560050244591 0.2730165170411156 GSRPPLILQSQSLPCS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 GSRPPLILQSQSLPCSSPR 19 1 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 GSRPPLILQSQS(0.007)LPCS(0.612)S(0.381)PR 96.777 0.00030201 91964000.0 151860.0 100020.0 83430.0 83554.0 82670.0 93543.0 85862.0 56513.0 82561.0 59571.0 True False 149694.4485522865 99788.40983521049 76570.70744911341 89698.83988797318 77807.51313547352 89542.38394938331 90307.51423400734 59138.80029084952 73262.11077412756 69867.76797663188 2.1425394411104364 1.4282467112529764 1.095937506901944 1.2838372039875963 1.1136395993285084 1.281597889019896 1.2925490086388873 0.8464389518014832 1.0485823849222 1.0 16.09233943164879 -4.710721096484393 1.9390085037281357 1.1290284531620005 2.584935974949217 0.841267502640475 0.13454908745726848 0.3829018950044464 1.3299174447074806 0.03825991931716284 1.073592015947682 1.9466097913105835e-05 4.710721096484393 1.4559075217872166 up GSRPPLILQSQSLPCSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 GSRPPLILQSQSLPCSSPR 19 1 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 GSRPPLILQSQS(0.001)LPCS(0.06)S(0.938)PR 73.688 0.022747999999999997 18956000.0 26756.0 25118.0 38074.0 47226.0 38953.0 34900.0 29095.0 46656.0 35514.0 30690.0 True False 35263.851440627324 33236.9022907386 37569.11388289032 36338.77533442664 33545.04832772327 32717.697482904074 31684.398635516547 39446.38724822213 37391.19753673203 29615.55244130898 1.1907207036070637 1.1222786526304476 1.268560293019805 1.2270166294024565 1.1326835247865668 1.1047471610648767 1.0698567483523236 1.331948385105952 1.2625527621283625 1.0 14.854067377615612 -6.259652303632909 24.917025423445924 1.1605959025255101 1.201183411741374 0.06114957109255437 0.09445746404729928 698.6634611238886 9741325.08688476 0.030061593446825595 0.03676837324042021 5.499810127046568e-07 6.259652303632909 0.04058750921586385 GSRPPLILQSQSLPCSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 GSRPPLILQSQSLPCSSPR 19 1 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 GSRPPLILQS(0.002)QS(0.031)LPCS(0.345)S(0.623)PR 89.374 0.005118500000000001 11491000.0 31714.0 34082.0 34176.0 26499.0 30682.0 39578.0 34941.0 33342.0 30851.0 23639.0 True False 31261.75254436468 34003.08522299185 31366.18120317507 28447.824858072636 28877.345083132896 37885.34120082417 36750.07401237395 34891.19104095525 27376.235504567616 27724.96965301243 1.127566700184574 1.2264426489389242 1.131333292542198 1.0260723533373342 1.0415645335069015 1.3664700692181921 1.3255226055181961 1.2584753555235788 0.987421658064577 1.0 14.758898260803074 -8.27393219238015 24.080705603929566 0.9937107362741057 1.1875916046002493 0.35054689113065474 0.10574301562143425 672.7929240950718 1296830.5165208639 0.11141430342792946 0.029696554274364254 5.321913453130774e-09 8.27393219238015 0.1938808683261436 GSS(ph)DAS(ph)LLPLGRAAGGISR ddPTM_PC-9_AZD4547_30min_R2 1 GSSDASLLPLGRAAGGISR 19 1 Q8TC59-2;Q8TC59 Q8TC59-2 PIWIL2 Piwi-like protein 2 2 GS(0.435)S(0.565)DAS(1)LLPLGRAAGGISR 97.081 0.018601 19495000.0 16342.0 19923.0 77309.0 106260.0 78178.0 55527.0 22680.0 87399.0 38620.0 47672.0 True False 21538.416065283745 26362.720134500556 76283.83214719682 81763.39870063472 67324.3341505083 52054.88791212653 24698.47606301822 73893.49277922181 40661.374355707354 46003.0177902275 0.46819572062638 0.5730650161846736 1.6582353900139553 1.7773485877268653 1.4634764714242314 1.1315537634834172 0.5368881705900815 1.6062748995332026 0.8838849342693582 1.0 15.489440884375401 -5.168555016500849 7.005763710599658 1.273766959602341 0.5032880272452802 0.39271315376551175 0.36630692713570373 0.2662194660036219 17.221709029086536 0.09861133734631543 0.2660099987521351 6.78336183308883e-06 5.168555016500849 -0.7704789323570609 GSS(ph)DGRGSDSESDLPHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSSDGRGSDSESDLPHR 17 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 GS(0.466)S(0.488)DGRGS(0.039)DS(0.003)ES(0.003)DLPHR 51.466 0.035063 17339000.0 7790.9 9412.6 14766.0 13594.0 18446.0 16924.0 12152.0 11507.0 10924.0 10797.0 True False 9109.745492710897 10347.020722293722 15118.077440366847 12832.372252342646 14831.638715718955 16036.47564700073 11000.874587138827 11204.953442674307 11083.742833822405 12754.410630995024 0.7142427632503007 0.8112503996969486 1.185321523491472 1.006112522452285 1.162863510108101 1.2573278461044546 0.862515321594331 0.8785159712080057 0.8690125443262224 1.0 13.638708614484681 -5.078181748337506 5.811039374762138 1.0292545842447363 0.7357647292860605 0.4026692820236413 0.13135014081243598 0.2098952817408062 11.867431169927217 0.0368419491114244 0.10385545552160587 8.352533990393501e-06 5.078181748337506 -0.29348985495867574 GSS(ph)FQSGR ddPTM_PC-9_AZD4547_30min_R2 2 GSSFQSGR 8 0 Q96KP1 Q96KP1 EXOC2 Exocyst complex component 2 1 GSS(0.999)FQSGR;GS(0.004)S(0.995)FQSGR 128.51 0.0034639000000000002 99965000.0 298630.0 393900.0 421810.0 432100.0 386940.0 419240.0 368220.0 494930.0 387360.0 387510.0 True False 393588.12811012723 521220.47186567116 416216.5237942425 332486.0208784513 333220.06007057807 393024.8565252919 400990.86666334124 418449.94085996546 407835.0587888862 373943.3928488652 1.052533981444624 1.3938485926834658 1.1130468722105824 0.8891346317030142 0.8910976004468514 1.0510276797005444 1.0723303963426563 1.1190194795849442 1.090633145519217 1.0 18.51246036744483 -5.519109243446542 24.982138302954688 1.0182840447301682 1.2307554150939792 0.38295917703569804 0.10532222308172857 143.4059923448738 950412.6739798292 0.029296218928511284 0.05224556043494882 3.026152126994047e-06 5.519109243446542 0.21247137036381103 GSS(ph)FQSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GSSFQSGR 8 0 Q96KP1 Q96KP1 EXOC2 Exocyst complex component 2 1 GS(0.221)S(0.609)FQS(0.17)GR;GS(0.005)S(0.995)FQSGR;GS(0.032)S(0.966)FQS(0.002)GR;GS(0.055)S(0.945)FQSGR 118.23 0.003512 77198000.0 363486.0 483012.0 477591.0 375091.0 518171.0 358610.0 441363.0 343405.0 389759.0 295056.0 True False 425017.00062425446 530962.2392448985 488978.58071395266 354075.8673314293 416639.1122716462 339803.8603031753 399553.9014485966 334390.98261767306 395458.4880234146 348547.3171379889 1.2193954155613007 1.5233576996224363 1.4029044455974606 1.015861692004508 1.1953588272971842 0.9749145771466313 1.146340487510952 0.9593847554571439 1.134590537866208 1.0 18.410994997292356 -5.757002131643218 24.999830023712533 1.0648062904186792 1.396033132178667 0.679277806973223 0.10090141601572675 57.758340055018465 325409.95938725723 0.02586376369256773 0.042905268691865436 1.7498380998909112e-06 5.757002131643218 0.33122684175998773 GSS(ph)FQSGR ddPTM_PC-9_Lapatinib_30min_R1 2 GSSFQSGR 8 0 Q96KP1 Q96KP1 EXOC2 Exocyst complex component 2 1 GS(0.041)S(0.955)FQS(0.004)GR;GS(0.007)S(0.991)FQS(0.002)GR 109.16 0.0037825000000000003 89093000.0 124354.0 226303.0 212753.0 202990.0 227872.0 229887.0 259643.0 278791.0 227026.0 174287.0 True False 122580.68915626947 225779.0093075152 195261.26959032938 217918.56175478973 214469.01697358937 220055.26890277074 273086.04409704375 291744.64763658267 201455.94119023613 204412.2757271701 0.5996738146973052 1.1045276439701859 0.9552325998803779 1.0660737520756656 1.0491983233915072 1.0765266817756063 1.3359571636565153 1.4272364347920838 0.9855373923781378 1.0 17.641122312585736 -4.1901144455735375 0.6300005260472646 1.1791074235747032 1.3680695760725915e-17 0.4603834262883464 0.15503862322412906 6.330219282937628 1.108242506967142 0.072308340026083 6.366035776923234 6.454841082147683e-05 4.1901144455735375 -1.1791074235747032 GSS(ph)GSPAHAESYSSGGGGQQK ddPTM_PC-9_AZD4547_30min_R2 2 GSSGSPAHAESYSSGGGGQQK 21 0 P15408 P15408 FOSL2 Fos-related antigen 2 1 GS(0.298)S(0.395)GS(0.307)PAHAESYSSGGGGQQK;GS(0.008)S(0.601)GS(0.391)PAHAESYSSGGGGQQK 202.81 1.7218e-20 8044900.0 10224.699999999999 7948.8099999999995 34932.4 60694.5 50492.2 40520.0 28296.1 56651.0 29872.7 46828.4 True False 13475.941913028199 10518.107385048408 34469.17355157531 46702.32074567729 43482.229588813905 37986.27799447776 30814.398083190892 47896.889660473105 31451.70993567424 45188.95196945563 0.29821319870699664 0.2327583828931874 0.7627787777612968 1.0334897958519724 0.9622314236941069 0.8406098468526921 0.6819011448643273 1.0599247730473556 0.6960044118069668 1.0 15.46368247769574 -5.3352896105843115 3.968795901792048 0.8903535741733699 0.2599045212531236 0.797652728432089 0.12491013325558027 0.08707081453256404 2.6209843310583336 0.032646004825888315 0.07604256595799759 4.620727840073667e-06 5.3352896105843115 -0.6304490529202463 down GSS(ph)GSPAHAESYSSGGGGQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSSGSPAHAESYSSGGGGQQK 21 0 P15408 P15408 FOSL2 Fos-related antigen 2 1 GS(0.104)S(0.448)GS(0.448)PAHAESYSSGGGGQQK 122.97 7.073600000000001e-07 6973100.0 9910.2 11098.0 28594.0 33048.0 42408.0 40908.0 28056.0 30745.0 33350.0 26136.0 True False 11587.801124627902 12199.736095873151 29275.78940334886 31196.427703061596 34098.4568283752 38762.7124655818 25398.332572149982 29937.97632702022 33837.680657998666 30874.249907537833 0.3753225150191838 0.39514275269549565 0.9482267420592876 1.010435161874009 1.1044302916020055 1.2555029703286176 0.822638044590974 0.9696746128789666 1.0959838946479903 1.0 14.91411646627686 -5.291183554606774 3.5513346984457117 1.0356773133139088 0.3655876324676519 0.8587490684976862 0.10442908329878958 0.07924275185305553 2.1163136666466635 0.029531393117420358 0.07635878297360786 5.1146561885589945e-06 5.291183554606774 -0.6700896808462569 down GSS(ph)LSGTDDGAQEVVK ddPTM_PC-9_AZD4547_30min_R2 1 GSSLSGTDDGAQEVVK 16 0 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 1 GS(0.001)S(0.997)LS(0.003)GTDDGAQEVVK 184.87 7.1475e-08 14505000.0 62802.0 85048.0 81731.0 74909.0 60254.0 78827.0 89579.0 102590.0 99092.0 76548.0 True False 82771.72963725051 112538.10279571357 80647.19353791325 57639.88738251304 51888.772159747336 73897.93522879321 97551.35746248263 86737.07278367449 104329.80081967244 73868.07781939793 1.120534499890756 1.5235011674577619 1.0917732790487626 0.7803084780876303 0.7024519073937676 1.000404199084052 1.320615891765704 1.1742159176761078 1.4123800686238404 1.0 16.172663416162337 -9.280364535883011 15.751397252023104 1.0000341737034293 1.1168184431646826 0.022075799933568452 0.24427593252262822 0.0 0.0 0.2631406549793973 0.0638209832278982 5.243671348703966e-10 9.280364535883011 0.11678426946125331 GSS(ph)LSGTDDGAQEVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSSLSGTDDGAQEVVK 16 0 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 1 GS(0.053)S(0.947)LSGTDDGAQEVVK;GS(0.058)S(0.941)LS(0.001)GTDDGAQEVVK 184.92 7.103799999999999e-08 14675100.0 26654.0 48984.0 48183.0 30938.0 47539.0 33852.0 50245.0 29673.0 38981.0 38335.0 True False 31165.99575950354 53846.80779602184 49331.86545504506 29204.644162349305 38224.07421156691 32076.74152695986 45485.42985770164 28894.115191142322 39551.023380193255 45284.832040306974 0.6882215160202739 1.1890693940985373 1.0893684095181344 0.6449100691453361 0.8440811744105522 0.7083330131026897 1.004429691098691 0.6380528289345171 0.8733834619280427 1.0 15.46674028623188 -5.7469404264952 24.997130136362305 0.8056027896798182 1.0089047448934654 0.17372108816462506 0.1698603294604619 343.5309014458163 592264.5285173062 0.043745440185413584 0.0753373889530158 1.7908514937740604e-06 5.7469404264952 0.20330195521364713 GSS(ph)LSGTDDGAQEVVK ddPTM_PC-9_Lapatinib_30min_R1 1 GSSLSGTDDGAQEVVK 16 0 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 1 GS(0.004)S(0.97)LS(0.025)GTDDGAQEVVK 215.15 5.5917e-22 15938000.0 48300.0 63342.0 53299.0 50511.0 61653.0 79975.0 77716.0 80038.0 71888.0 55101.0 True False 47611.23314286478 63195.33549072089 48916.961960089764 54225.74743975649 58026.691754461695 76554.65568083065 81739.75421269154 83756.85767308447 63791.21642580006 64625.13443253257 0.7367293478138914 0.9778754976006377 0.7569340070179376 0.8390813870780749 0.8978966506451213 1.1845956894797995 1.2648291555668068 1.2960415232950124 0.9870960731601557 1.0 15.979807756059364 -6.699307710869257 4.230468430001342 1.1736315787516591 0.8376264437481367 0.6483417510234325 0.11202541713006266 0.1262012527472447 4.506105726582956 0.03764896564050448 0.036713450146396494 1.998445408443517e-07 6.699307710869257 -0.33600513500352247 GSS(ph)PGPRPVEGTPASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSSPGPRPVEGTPASR 16 1 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 GS(0.224)S(0.776)PGPRPVEGTPASR 69.289 0.010265 156210000.0 56578.0 52888.0 55545.0 54030.0 67338.0 55490.0 60688.0 59630.0 49338.0 43505.0 True False 66155.53793356319 58138.371115384696 56869.403455585525 51002.87426762343 54143.602289877635 52580.00671543791 54939.19329692899 58064.775683207496 50059.47491167426 51392.112114609496 1.2872702679747778 1.1312703199613663 1.1065784439596709 0.9924261169473241 1.0535391534236236 1.0231143370441613 1.0690199533813507 1.129838282453099 0.9740692268112405 1.0 15.64925932483625 -4.580467612403923 1.2261988410819094 1.0428537683532746 1.4906462987004594 0.7414221481927179 0.04491547098311521 1.1306455821555543 1.0671491548239775 0.013303915965919583 0.7230142600575659 2.6274374608262693e-05 4.580467612403923 0.4477925303471848 GSS(ph)PLGPAGLGAEEPAAGPQLPSWLQPER ddPTM_PC-9_AZD4547_30min_R2 1 GSSPLGPAGLGAEEPAAGPQLPSWLQPER 29 0 H0YKL4;O43482 H0YKL4 OIP5 Protein yippee-like;Protein Mis18-beta 1 GS(0.437)S(0.563)PLGPAGLGAEEPAAGPQLPSWLQPER 158.78 2.4199e-12 6402000.0 8722.0 9167.2 14751.0 22835.0 15736.0 15651.0 12897.0 17760.0 11474.0 14723.0 True False 11495.4145711299 12130.318125633357 14555.392101867814 17570.743547233124 13551.328023131804 14672.340495843315 14044.808015200442 15015.600084199792 12080.492215364742 14207.552251332432 0.8091059154860276 0.8537936662872899 1.024482743007527 1.2367185590033836 0.9538115914274335 1.0327141675278577 0.9885452305046616 1.0568745283193717 0.8502866645612226 1.0 13.794370400770088 -5.221140337850803 4.639323353208245 1.0252964050028937 0.8240912226262012 0.3991467278872245 0.0916133649169093 0.19581303729501973 10.035426663735883 0.02388574180282712 0.06534548426920814 6.0097950567969465e-06 5.221140337850803 -0.2012051823766925 GSS(ph)PLPTATTPKPLIPTEASIR ddPTM_PC-9_Lapatinib_30min_R1 2 GSSPLPTATTPKPLIPTEASIR 22 1 A0A3B3IUD2;Q9BUK6-7;Q9BUK6-3;Q9BUK6-2;Q9BUK6 A0A3B3IUD2 MSTO1 Protein misato homolog 1 1 GS(0.168)S(0.832)PLPTATTPKPLIPTEASIR;GS(0.33)S(0.666)PLPT(0.004)ATTPKPLIPTEASIR 95.926 7.4219e-05 9922600.0 26370.0 26067.0 24217.0 21593.7 22681.0 27307.0 21631.0 23960.8 26498.0 22901.0 True False 25993.958964334255 26006.643463051703 22225.971740323334 23181.77273247153 21346.948172561675 26139.14326572607 22750.94733870412 25074.106241200927 23513.516203689782 26859.407336335607 0.9677785752617644 0.9682508306082287 0.8274930069010076 0.8630783413121351 0.7947661653607436 0.97318391796251 0.8470383226932364 0.9335316273818332 0.8754294504436262 1.0 14.713139851017605 -10.334588000397467 6.8510398864476265 1.0000000007739542 0.8929115566479395 0.2145399598357366 0.060487041310031124 7.260399298331136e-10 1.9327225151564065e-10 0.059239943311433285 0.014367796571106983 4.628198738235841e-11 10.334588000397467 -0.1070884441260147 GSS(ph)PQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILK ddPTM_PC-9_AZD4547_30min_R2 1 GSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILK 38 1 Q27J81-2;Q27J81 Q27J81-2 INF2 Inverted formin-2 1 GS(0.117)S(0.354)PQNT(0.175)T(0.175)T(0.175)PKPS(0.006)VEGQQPAAAAACEPVDHAQSESILK 71.42 5.5601e-07 11059000.0 8099.6 5560.2 11427.0 15933.0 12335.0 9119.1 8258.8 17701.0 8410.1 13557.0 True False 10675.104317854137 7357.425914362793 11275.47051373083 12259.893012396125 10622.498167598556 8548.881235425519 8993.817200584424 14965.71717851467 8854.640716440566 13082.37355642965 0.8159914003225812 0.5623922816931648 0.8618826289507096 0.9371306330242117 0.8119702530874355 0.6534656114619173 0.6874759508884529 1.143960391740947 0.6768374774078163 1.0 13.675336694653925 -14.522878686347449 0.08998756092686412 1.6710016917071011 0.6281634928688655 0.14128136894481724 0.15639037628944125 420.6147453498764 2.620153628071144 53.85429327254546 3.753697833590527 3.0000004070940022e-15 14.522878686347449 -1.0428381988382356 GSS(ph)PQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILK 38 1 Q27J81-2;Q27J81 Q27J81-2 INF2 Inverted formin-2 1 GS(0.202)S(0.692)PQNT(0.034)T(0.034)T(0.034)PKPS(0.006)VEGQQPAAAAACEPVDHAQSESILK 94.631 5.743700000000001e-20 29048000.0 62786.0 65305.0 77061.0 101470.0 107920.0 95305.0 99776.0 71220.0 90129.0 71215.0 True False 73414.42971997413 71788.0488142904 78898.42649546987 95784.96487017865 86773.85071020196 90307.03802513615 90324.4949643154 69350.55046382768 91446.96611768394 84125.71576236999 0.8726752462629614 0.8533425025121949 0.9378633605725787 1.1385931638399673 1.0314783051036638 1.0734772026216877 1.0736847127631592 0.8243680286741603 1.0870274955638333 1.0 16.360259254130398 -5.528527684797661 24.357362096933016 1.029436616943305 0.8711573619972355 0.4323202071376787 0.07897645864159639 98.35938140267514 424108.9829684106 0.021884153793742287 0.03806779493516721 2.961231190950229e-06 5.528527684797661 -0.15827925494606943 GSS(ph)PQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILK ddPTM_PC-9_Lapatinib_30min_R1 1 GSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILK 38 1 Q27J81-2;Q27J81 Q27J81-2 INF2 Inverted formin-2 1 GS(0.162)S(0.653)PQNT(0.06)T(0.06)T(0.06)PKPS(0.004)VEGQQPAAAAACEPVDHAQSESILK 89.973 1.8099e-14 29243000.0 47880.0 55072.0 68267.0 50918.0 68872.0 64322.0 52412.0 57746.0 73618.0 49380.0 True False 47197.22241988337 54944.48416761363 62654.35077824063 54662.679577468676 64821.08436756174 61571.09800190543 55125.63690611441 60429.08997213738 65326.3656080925 57915.26720528591 0.8149357621469403 0.9487046649177655 1.0818278806546227 0.9438388565783847 1.1192400120990125 1.0631237836417313 0.9518325575658072 1.0434051829190565 1.1279645033240937 1.0 15.821656090768137 -4.8790775407431095 2.569027182575913 1.0399145615133913 0.7911233785578381 0.5809487355669777 0.059545438219889564 0.27912505581365255 2.819776315870727 0.015399980341200856 0.13952805288382567 1.3210597456274252e-05 4.8790775407431095 -0.24879118295555325 GSS(ph)PTPPCSPVQPSK ddPTM_PC-9_AZD4547_30min_R2 1 GSSPTPPCSPVQPSK 15 0 H0YBY0;E7EPX0;E7EVJ4;Q9NUL3-4;Q9NUL3-6;Q9NUL3-8;Q9NUL3-3;Q9NUL3-7;Q9NUL3-2;Q9NUL3 H0YBY0 STAU2 Double-stranded RNA-binding protein Staufen homolog 2 1 GS(0.141)S(0.859)PTPPCSPVQPSK 222.75 1.2264000000000002e-19 20946000.0 34827.0 35905.0 53941.0 64801.0 57437.0 51924.0 35926.0 61401.0 44256.0 49590.0 True False 45901.261553398435 47510.58908945655 53225.70709557674 49862.13061546984 49462.86398478784 48677.18407169947 39123.344402116054 51912.886304614345 46595.281809585336 47853.869194021245 0.9591964521676177 0.9928264921866009 1.1122550379317424 1.041966542210123 1.0336230866566505 1.0172047713496297 0.8175586438683214 1.0848210850858477 0.9736993600385159 1.0 15.546347957162597 -7.022366803869313 24.98690845188787 0.9677015627582867 1.030873960511634 0.13469758843587465 0.0711883411081672 1551.2950997422952 1733012.7590675459 0.02725276933692465 0.02128333308015047 9.498022545426637e-08 7.022366803869313 0.06317239775334726 GSS(ph)PTPPCSPVQPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GSSPTPPCSPVQPSK 15 0 H0YBY0;E7EPX0;E7EVJ4;Q9NUL3-4;Q9NUL3-6;Q9NUL3-8;Q9NUL3-3;Q9NUL3-7;Q9NUL3-2;Q9NUL3 H0YBY0 STAU2 Double-stranded RNA-binding protein Staufen homolog 2 1 GS(0.178)S(0.806)PT(0.016)PPCSPVQPSK;GS(0.007)S(0.993)PTPPCSPVQPSK;GS(0.019)S(0.981)PTPPCSPVQPSK 255.72 6.1357e-50 35591000.0 103782.0 102966.0 141491.0 150310.0 168896.0 119429.0 119731.0 126475.0 108869.0 91424.0 True False 121350.24281206558 113187.78400141269 144864.6820476058 141888.618011595 135802.04123008088 113165.93299726144 108389.21290262644 123155.16526133954 110461.00316508711 107998.44748801428 1.123629511669907 1.0480501028866578 1.341358930772435 1.3138023861624666 1.2574443835884979 1.047847775865673 1.0036182502961954 1.1403419968144206 1.0228017692323412 1.0 16.72065104777517 -6.769036927064734 24.693285792646797 1.0492368076125818 1.2197815238430947 0.49380640109086604 0.08791051907472575 147.17914306691262 478352.9294685386 0.03377146237759123 0.030351869591241348 1.702013783909876e-07 6.769036927064734 0.17054471623051293 GSS(ph)PTPPCSPVQPSK ddPTM_PC-9_Lapatinib_30min_R1 3 GSSPTPPCSPVQPSK 15 0 H0YBY0;E7EPX0;E7EVJ4;Q9NUL3-4;Q9NUL3-6;Q9NUL3-8;Q9NUL3-3;Q9NUL3-7;Q9NUL3-2;Q9NUL3 H0YBY0 STAU2 Double-stranded RNA-binding protein Staufen homolog 2 1 GS(0.175)S(0.797)PT(0.028)PPCSPVQPSK;GS(0.016)S(0.984)PTPPCSPVQPSK;GSS(0.999)PTPPCSPVQPSK 246.77 3.1651999999999995e-40 44397000.0 121248.0 134379.0 153825.0 143840.0 124694.0 102407.0 89049.8 86513.1 112837.0 79217.6 True False 119518.9812858399 134067.853681721 141178.10228167116 154418.4734361737 117359.74407783627 98027.2913323767 93660.36291998228 90532.81445759899 100128.1088337136 92910.25660918288 1.286391682121639 1.442982277464405 1.5195104118108493 1.6620175110022415 1.2631516515070835 1.055075025190363 1.0080734499954578 0.974411413353594 1.0776862801584097 1.0 16.503550247873477 -6.597073147317476 3.186736362064904 1.01876658793714 1.4785204086271875 0.8449649019310768 0.09161317499872379 0.09620029913643816 1.9742546232753662 0.03359579927959571 0.03413944555114603 2.528872027911931e-07 6.597073147317476 0.45975382069004755 GSS(ph)QPNLSTSHSEQEYGK ddPTM_PC-9_AZD4547_30min_R2 2 GSSQPNLSTSHSEQEYGK 18 0 F6PQP6;E9PBC1;I3L2B2;O95208-2;O95208;O95208-3 F6PQP6 EPN2 Epsin-2 1 GS(0.165)S(0.834)QPNLS(0.001)TSHSEQEYGK;GS(0.127)S(0.562)QPNLS(0.262)T(0.04)S(0.009)HSEQEYGK 108.96 0.00025987 18065300.0 19030.2 21688.0 60396.0 100752.0 81070.0 70913.0 46361.0 80608.0 51023.0 61966.0 True False 25081.40774725021 28698.221868044373 59595.10957795466 77525.18300288287 69814.82987006202 66478.79889986188 50487.03918684251 68151.88578756635 53719.971614481015 59796.589200982475 0.41944545805027483 0.4799307494209528 0.996630583354 1.2964816896547857 1.1675386640433154 1.1117490109079602 0.8443130262354995 1.1397286483765967 0.8983785251349818 1.0 15.867775574956692 -5.272659334187784 4.14651178980222 1.0731991432925 0.43319628110886493 0.7942422496963242 0.12408974237829777 0.08470916337955631 3.5663119322990124 0.03416745067635217 0.08622529021082266 5.337534139147904e-06 5.272659334187784 -0.6400028621836351 down GSS(ph)QPNLSTSHSEQEYGK ddPTM_PC-9_Lapatinib_30min_R1 1 GSSQPNLSTSHSEQEYGK 18 0 F6PQP6;E9PBC1;I3L2B2;O95208-2;O95208;O95208-3 F6PQP6 EPN2 Epsin-2 1 GS(0.198)S(0.74)QPNLS(0.046)T(0.015)SHSEQEYGK 92.551 0.00063795 36114000.0 52441.0 43633.0 85827.0 45847.0 69621.0 72143.0 47927.0 50365.0 82828.0 42685.0 True False 51693.18172349838 43531.97046930351 78770.63536180071 49218.741321108595 65526.0296601524 69057.61206354688 50408.425551388 52705.14176647206 73499.03842249291 50063.0453758127 1.0325616696996476 0.8695429960865986 1.5734287590873908 0.9831351838793247 1.3088702288936351 1.3794129291405666 1.0068989046308032 1.05277538293617 1.4681295928114475 1.0 15.611458433559081 -5.157419433327484 19.918848585479335 1.2165412967292148 0.9510276267174619 0.2213153323453224 0.20277428838494954 10.136891499674906 1933.12568236982 0.04915767061296617 0.1300609763117237 6.959540502885764e-06 5.157419433327484 -0.26551367001175297 GSS(ph)SQGPSQTSTPTDVTAIHL ddPTM_PC-9_AZD4547_30min_R2 1 GSSSQGPSQTSTPTDVTAIHL 21 0 Q5T8J1;P30281-4;P30281-2;P30281-3;P30281 Q5T8J1 CCND3 G1/S-specific cyclin-D3 1 GS(0.124)S(0.736)S(0.124)QGPS(0.014)QT(0.001)S(0.001)T(0.002)PTDVTAIHL 225.86 2.3735999999999995e-108 0.0 2500.9 2836.9 4266.5 5784.0 4412.4 4743.0 2503.5 4414.0 3519.0 3682.8 True False 3296.1341780484718 3753.872446396858 4209.923422318423 4450.5881619091915 3799.814423568045 4446.419460212435 2726.30665007787 3731.9177236293835 3705.0071558191157 3553.866292957076 0.9274783872934758 1.0562784688428337 1.1846037738283788 1.252322905543522 1.0692057917593525 1.2511499008908098 0.7671382166179876 1.0501007680072725 1.0425285732222298 1.0 11.795173688562043 -7.242735170984744 24.998043650941426 0.9691169150964936 1.1266149274737949 0.3064614829451314 0.11673448718702444 1069.286497113614 1429095.8668188804 0.045674335958314105 0.03531650870614838 5.718272256695337e-08 7.242735170984744 0.15749801237730132 GSS(ph)SQGPSQTSTPTDVTAIHL ddPTM_PC-9_Lapatinib_30min_R1 1 GSSSQGPSQTSTPTDVTAIHL 21 0 Q5T8J1;P30281-4;P30281-2;P30281-3;P30281 Q5T8J1 CCND3 G1/S-specific cyclin-D3 1 GS(0.165)S(0.67)S(0.165)QGPSQTSTPTDVTAIHL 107.63 6.2741e-05 3495500.0 12836.0 10458.0 13252.0 10803.0 11516.0 11195.0 10262.0 12072.0 13567.0 9649.9 True False 12652.956286165883 10433.785143537605 12162.471714199315 11597.488657751568 10838.651521327123 10716.215946819615 10793.316147648371 12632.909191002695 12038.941593156429 11317.872357316503 1.1179624479495307 0.9218857409001106 1.0746252767497255 1.0247057301591058 0.957658045535424 0.9468401487928123 0.9536524009895704 1.1161911702278635 1.0637106704400838 1.0 13.466315151495658 -7.758705183491096 24.994461972136186 1.0674631862210493 0.99683478374656 0.15671324161347455 0.06321092668150173 112.72811859987314 1030528.85709763 0.030701062187254304 0.0167028871582729 1.742989683165168e-08 7.758705183491096 -0.07062840247448932 GSS(ph)TPTKGIENK ddPTM_PC-9_Lapatinib_30min_R1 1 GSSTPTKGIENK 12 1 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9;H0YBE9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 GS(0.107)S(0.587)T(0.306)PTKGIENK 87.719 0.040665 5213000.0 109460.0 37209.0 61851.0 51515.0 42445.0 44870.0 23793.0 26351.0 59144.0 32542.0 True False 107899.08032749449 37122.84484661415 56765.84953176442 55303.58494900226 39948.46855008073 42951.014697078695 25024.8851199569 27575.363659055012 52482.57990606944 38166.84134051064 2.8270372013460126 0.9726465052587838 1.4873080280686632 1.4489955942542858 1.046679975261119 1.1253489465865254 0.6556708451897814 0.7224953045770195 1.3750831366378737 1.0 15.220032174671372 -3.3168050389813506 1.6990040125672168 1.074069431351068 199.99999840560253 0.7609056062580396 0.28611369047093205 80.36193209055901 2.612191023606886 0.08346796181554558 60606.65349140491 0.00048216419946963773 3.3168050389813506 198.92592897425146 up GSS(ph)VESLPPTSEGK ddPTM_PC-9_AZD4547_30min_R2 1 GSSVESLPPTSEGK 14 0 O43318-3;O43318;Q9UG54;O43318-4;O43318-2 O43318-3 MAP3K7;DKFZp586F0420 Mitogen-activated protein kinase kinase kinase 7 1 GS(0.196)S(0.804)VESLPPTSEGK 156.24 0.00035136 4982600.0 11391.0 13587.0 15782.0 21662.0 20564.0 17121.0 13239.0 17441.0 15053.0 14399.0 True False 15013.10105248116 17978.73204173362 15572.720368224385 16668.160574563783 17709.043560478043 16050.421163461346 14417.245352658654 14745.894204309026 15848.670848691436 13894.895392714496 1.0804760041844557 1.2939091323537708 1.1207511771833578 1.199588777278841 1.2744999555565866 1.1551307663587778 1.0375929393623244 1.061245427730297 1.1406110230237043 1.0 13.762267352844303 -7.100222098909338 4.710218564073668 1.066049347864138 1.197313057181711 0.46561481030411633 0.06764589508853219 0.2038804891978736 7.3424521960023155 0.02523844098401636 0.019522677594527856 7.939221178173598e-08 7.100222098909338 0.13126370931757303 GSS(ph)VESLPPTSEGK ddPTM_PC-9_Lapatinib_30min_R1 1 GSSVESLPPTSEGK 14 0 O43318-3;O43318;Q9UG54;O43318-4;O43318-2 O43318-3 MAP3K7;DKFZp586F0420 Mitogen-activated protein kinase kinase kinase 7 1 GS(0.146)S(0.854)VESLPPTSEGK 116.63 0.0017603999999999999 0.0 12924.0 14268.0 12350.0 12451.0 11303.0 11677.0 10613.0 12178.0 13226.0 14469.0 True False 12739.701390028666 14234.963322623313 11334.630672378633 13366.688075318396 10638.179762553007 11177.6019304165 11162.489210192178 12743.83433797473 11736.348604045625 16969.947371269376 0.750721325842021 0.8388336752725307 0.667923737440017 0.7876682103297854 0.6268834858358937 0.6586703945435041 0.6577798366711851 0.7509648709665664 0.6915960519662901 1.0 14.050694470221044 -10.811906342903034 4.866932797138281 1.0000990473280693 0.7141720288790175 0.6461258010837683 0.06337204336609936 7.072734287677289e-05 1.0332036186513145e-05 0.06371860233951956 0.015448696996132848 1.542032961800531e-11 10.811906342903034 -0.2859270184490518 GSS(ph)YSSIPK ddPTM_PC-9_AZD4547_30min_R2 2 GSSYSSIPK 9 0 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 1 GS(0.001)S(0.997)YS(0.002)SIPK;GS(0.211)S(0.787)YS(0.002)SIPK 133.75 0.0011541 122835000.0 850300.0 921620.0 1203030.0 1498080.0 1130990.0 1119700.0 1116060.0 1256730.0 1005950.0 983750.0 True False 1120677.7126612898 1219515.641738614 1187077.036154163 1152720.801105276 973971.5608084567 1049684.9819944894 1215387.1779052964 1062531.2552824558 1059122.4633123728 949309.2119301958 1.1805191591711797 1.2846347917124046 1.2504640439973427 1.214273270098676 1.0259792579365326 1.1057355904723638 1.280285878016599 1.1192678233070654 1.115677010190281 1.0 19.8565185573187 -14.52287874496971 0.03257468564294366 1.3046261433250597e-06 1.8217040162655191 0.41384841804504635 0.07328609606617283 1341.283120159318 3.2711425381865613 148.26958771902432 55.46146300963245 3.0000000021457433e-15 14.52287874496971 1.8217027116393758 GSS(ph)YSSIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GSSYSSIPK 9 0 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 1 GS(0.05)S(0.947)YS(0.003)S(0.001)IPK;GS(0.021)S(0.979)YSSIPK;GS(0.006)S(0.991)YS(0.002)SIPK;GSS(0.998)YS(0.002)SIPK 147.3 0.00038937 62973500.0 322885.0 361542.0 421883.0 460525.0 652756.0 793126.0 924926.0 994500.0 838752.0 661115.0 True False 377543.05323055893 397433.50041216245 431942.2907201864 434723.2772921948 524853.1476481525 751533.076341474 837310.3133956534 968395.4287598513 851017.1612371128 780969.9161165403 0.4834284207872356 0.5088973239692057 0.5530844169620098 0.5566453563972151 0.6720529649311502 0.9623073319886067 1.0721415718024991 1.2399906946163881 1.0896926292230182 1.0 19.5749074495577 -6.769858890016098 1.6186783094092512 1.127667157707343 0.5184029730732826 0.9525369490033294 0.059165175151094734 0.06934655396744416 0.3768223633797702 0.02536856661530594 0.02292040395336849 1.6987955316132595e-07 6.769858890016098 -0.6092641846340603 GSSAAASPGS(ph)PPPGR ddPTM_PC-9_AZD4547_30min_R2 3 GSSAAASPGSPPPGR 15 0 Q86UX6 Q86UX6 STK32C Serine/threonine-protein kinase 32C 1 GSSAAAS(0.013)PGS(0.987)PPPGR;GSSAAASPGS(1)PPPGR;GSSAAAS(0.005)PGS(0.995)PPPGR 166.52 0.00013744 12393000.0 15245.899999999998 16381.2 25708.199999999997 30882.9 23296.6 23488.4 19477.2 22143.0 18296.0 21043.9 True False 20093.779065580075 21676.10254817449 25367.292470560507 23763.324541048645 20062.269218587455 22019.666634883804 21210.63306766396 18721.308145520044 19263.089207975696 20307.159466264657 0.989492356080669 1.0674118447823289 1.2491797541995973 1.1701944124940544 0.9879406941141115 1.0843302172056144 1.0444903977289488 0.9219067874372527 0.948586100383787 1.0 14.309700831368021 -7.2867106704112485 1.1711264075233894 0.951701805170421 1.1097314086018504 0.3706300932503541 0.07617751956152373 0.5387948483169678 1.4322969788238158 0.05613587990586216 0.03132482312538653 5.167605235808599e-08 7.2867106704112485 0.15802960343142936 GSSAAASPGS(ph)PPPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSSAAASPGSPPPGR 15 0 Q86UX6 Q86UX6 STK32C Serine/threonine-protein kinase 32C 1 GSSAAAS(0.082)PGS(0.918)PPPGR;GSSAAAS(0.016)PGS(0.984)PPPGR 150.12 7.0703e-05 6002300.0 9793.2 11782.1 12309.3 13713.9 15391.5 13610.5 14821.4 13962.1 11752.3 12143.5 True False 11450.995335483238 12951.749022813763 12602.800395280206 12945.554644063684 12375.646063807228 12896.741420084103 13417.409694356425 13595.609669067771 11924.155154332762 14345.020422106893 0.798255770890105 0.9028742129118213 0.8785487942462754 0.902442399044165 0.8627137292000859 0.8990395998467267 0.9353356983500044 0.9477581257476486 0.8312400263966602 1.0 13.808262401532037 -14.522878744532473 0.05250489538916715 1.3904146324429658 0.6982204033664388 0.4367689111952371 0.041311024372352415 504.42646238801393 1.9456237329062256 27.57518904681816 5.7026703748758365 3.0000000051660626e-15 14.522878744532473 -0.6921942290765271 GSSAAASPGS(ph)PPPGR ddPTM_PC-9_Lapatinib_30min_R1 3 GSSAAASPGSPPPGR 15 0 Q86UX6 Q86UX6 STK32C Serine/threonine-protein kinase 32C 1 GS(0.001)S(0.001)AAAS(0.233)PGS(0.766)PPPGR;GSSAAAS(0.002)PGS(0.998)PPPGR;GSSAAAS(0.052)PGS(0.948)PPPGR 160.63 0.00028736 12237000.0 27499.5 26548.4 25462.5 22668.399999999998 29960.2 27000.2 29811.2 26462.899999999998 27425.8 16855.4 True False 27107.352087209332 26486.928810928846 23369.07153809236 24335.509755565632 28197.999940019512 25845.464386540316 31354.678068678153 27692.462941566064 24336.817597522633 19768.833431591273 1.3712165758800343 1.3398326665346791 1.182116871941861 1.2310038343828955 1.426386642266819 1.3073843975658361 1.5860661772066076 1.4008142178643965 1.231069991142298 1.0 14.27094011899722 -8.59277922091651 3.8088949454757763 1.0002310367321927 1.3526301687540114 0.5214077545567805 0.10434917223829367 0.279636850403633 10.873559049962127 0.10970635072970965 0.028801710040784984 2.5539993305065768e-09 8.59277922091651 0.3523991320218187 GSSANASKWS(ph)PPQNYK ddPTM_PC-9_AZD4547_30min_R2 2 GSSANASKWSPPQNYK 16 1 H3BRF9;Q96K21-3;Q96K21-2;Q96K21;H3BRM1 H3BRF9 ZFYVE19 Abscission/NoCut checkpoint regulator 1 GS(0.043)S(0.04)ANAS(0.01)KWS(0.902)PPQNY(0.004)K;GSSANAS(0.003)KWS(0.995)PPQNY(0.002)K 76.301 0.0054667000000000006 30326000.0 73386.0 34041.0 93951.0 209083.0 165931.0 93931.0 56047.0 84845.0 67744.0 98458.0 True False 96721.22147637462 45044.087541963236 92705.1483535071 160882.14465014872 142894.34482754735 88057.47972110796 61035.07442257412 71734.15479414024 71324.8095378829 95011.01538828276 1.0180000822126016 0.47409331810507416 0.975730529503845 1.693299918884874 1.5039766099075897 0.9268133738097872 0.6423999803932342 0.7550088218822136 0.7507004240129302 1.0 16.535807165885444 -6.995714511089227 24.95499292242308 0.7691820942391804 1.1284607697837283 0.21186718780327496 0.3152258437928063 213.1695181157781 1241304.360626528 0.12726266193403735 0.11178921154979275 1.0099165491969907e-07 6.995714511089227 0.35927867554454795 GSSDGRGS(ph)DSESDLPHR ddPTM_PC-9_AZD4547_30min_R2 1 GSSDGRGSDSESDLPHR 17 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 GS(0.153)S(0.153)DGRGS(0.565)DS(0.125)ES(0.003)DLPHR 52.966 0.027142000000000003 22180000.0 28676.0 29612.0 60539.0 71463.0 63563.0 55779.0 40126.0 58608.0 43109.0 52864.0 True False 37794.371502146394 39183.49990577878 59736.21330452008 54988.30944234383 54738.374627244986 52291.13031228959 43697.136265637935 49551.4802778593 45387.65373123224 51013.24745054933 0.7408736630378824 0.768104401582394 1.1709941297586774 1.0779221514107253 1.073022741402744 1.0250500198596257 0.8565840923575115 0.9713453417348695 0.8897228857117876 1.0 15.638584323681211 -5.155595130331825 7.81858178008558 1.0068461753789542 0.7493272291000057 0.580361953407803 0.08632042449964655 0.21128791788800702 13.902858733376803 0.024121024353485315 0.0646299435556704 6.988836325508856e-06 5.155595130331825 -0.25751894627894845 GSSDGRGS(ph)DSESDLPHR ddPTM_PC-9_Lapatinib_30min_R1 1 GSSDGRGSDSESDLPHR 17 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 GS(0.04)S(0.047)DGRGS(0.815)DS(0.051)ES(0.047)DLPHR 53.625 0.028338 18022000.0 15229.0 13751.0 22804.0 12393.0 15907.0 20432.0 14331.0 15780.0 21900.0 15266.0 True False 15011.831667343438 13719.160404358921 20929.143145985603 13304.422561836082 14971.381534365262 19558.170989318296 15072.98905787846 16513.196407722226 19433.39138277629 17904.707759333647 0.8384293041319166 0.7662320205816922 1.1689184446518168 0.7430684008176868 0.836170114341059 1.0923479596656753 0.8418450197837479 0.9222823756569815 1.0853788648209435 1.0 14.12805135072948 -1.5228787459524327 0.1472804689244119 1.0351115602094922 0.320983290758476 0.13021701721262136 0.13164907693132274 162.77422758407675 1.5842503442297242 0.4935968449015012 24.72322446040805 0.029999999953573313 1.5228787459524327 -0.7141282694510163 GSSGENNNPGS(ph)PTVSNFR ddPTM_PC-9_AZD4547_30min_R2 3 GSSGENNNPGSPTVSNFR 18 0 D6RDZ7;D6RD37;D6RAX8;D6RBL1;D6RDZ9;D6RCK9;Q99576-3;D6R8Z7 D6RDZ7 TSC22D3 1 GSSGENNNPGS(0.891)PT(0.109)VSNFR;GSSGENNNPGS(0.997)PT(0.003)VSNFR;GSSGENNNPGS(0.976)PT(0.024)VSNFR 246.42 1.7665e-53 24041100.0 50251.0 60202.0 71354.0 103777.0 90766.0 75271.0 58360.0 82255.0 60966.0 70351.0 True False 66229.77271426831 79661.11918572529 70407.79933812455 79852.81598866697 78164.7076352047 70564.29247093627 63553.92694169941 69544.37978186121 64188.538295444196 67888.03290317791 0.9755736008542977 1.1734191694630212 1.0371165038548154 1.1762428895613055 1.151376822873678 1.0394216690823146 0.9361580270316594 1.0243982158246592 0.945505938977346 1.0 16.050869662519467 -6.991068271097992 5.474569604102058 0.9792373701798149 1.1066649822289678 0.4762426776825639 0.06231149519698931 0.1424467843016252 14.03899686989696 0.02194510908602513 0.018495305657020317 1.0207790046220471e-07 6.991068271097992 0.12742761204915287 GSSGENNNPGS(ph)PTVSNFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSSGENNNPGSPTVSNFR 18 0 D6RDZ7;D6RD37;D6RAX8;D6RBL1;D6RDZ9;D6RCK9;Q99576-3;D6R8Z7 D6RDZ7 TSC22D3 1 GSSGENNNPGS(0.999)PT(0.001)VSNFR;GSSGENNNPGS(0.986)PT(0.014)VSNFR 242.94 2.7615999999999997e-53 12648700.0 28174.0 28101.0 24882.0 36428.0 42841.0 36100.0 41394.0 28712.0 30502.0 30146.0 True False 32943.30173813511 30890.681566960848 25475.281245510483 34387.057261169466 34446.61358669175 34206.85244958204 37472.86065339241 27958.34042287866 30948.034045885317 35611.231164395285 0.9250817975389849 0.8674421118539107 0.715372100669777 0.9656239376399385 0.9672963405188882 0.960563601175986 1.0522764708808612 0.7850989563885644 0.8690526284535675 1.0 15.120044693488662 -5.833995705291595 24.999999999987327 0.9402074269105521 0.8390896793446444 0.25311122841492684 0.08399723555712003 63.52918098706617 21887.980453397624 0.024836557305399107 0.03683858413374786 1.465562333729857e-06 5.833995705291595 -0.10111774756590775 GSSGENNNPGS(ph)PTVSNFR ddPTM_PC-9_Lapatinib_30min_R1 3 GSSGENNNPGSPTVSNFR 18 0 D6RDZ7;D6RD37;D6RAX8;D6RBL1;D6RDZ9;D6RCK9;Q99576-3;D6R8Z7 D6RDZ7 TSC22D3 1 GSSGENNNPGS(0.956)PT(0.044)VSNFR;GSSGENNNPGS(0.995)PT(0.005)VSNFR;GSSGENNNPGS(0.999)PT(0.001)VSNFR 221.81 8.919999999999999e-82 17660100.0 44999.4 41535.0 48482.2 33272.3 45229.9 60146.6 51613.3 55180.0 54193.6 37896.4 True False 44357.700304120684 41438.82825940281 44496.18066270405 35719.25593513907 42569.566207404765 57574.27012657261 54285.58412818354 57743.86424449379 48089.74608409243 44446.74224622111 0.9979966598765065 0.9323254341081875 1.0011123068640007 0.8036417098302844 0.9577657226615761 1.2953541073410753 1.221362497783489 1.2991697777220828 1.0819633488027134 1.0 15.439790059179076 -6.700752004855915 7.628782660962105 1.2005594821404362 0.932774463747732 0.5897349684046278 0.0997421914747393 0.14980108957744132 16.109287059093262 0.03187392481142588 0.03174018055302086 1.9918103976448466e-07 6.700752004855915 -0.2677850183927042 GSSGPQPAKPCSGATPTPLLLVGDRS(ph)PVPSPGSSSPQLQVK ddPTM_PC-9_Lapatinib_30min_R1 1 GSSGPQPAKPCSGATPTPLLLVGDRSPVPSPGSSSPQLQVK 41 2 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 GSSGPQPAKPCSGAT(0.002)PT(0.09)PLLLVGDRS(0.358)PVPS(0.312)PGS(0.079)S(0.079)S(0.079)PQLQVK 50.645 0.00045598 4518400.0 48259.0 14701.0 18832.0 17413.0 8496.2 15783.0 8359.0 10191.0 20678.0 8528.7 True False 47570.81781038328 14666.960737726746 17283.705653622215 18693.610108065164 7996.470220171891 15107.99788196999 8791.788119098881 10664.51106407459 18349.025891006753 10002.874431221588 4.755714783532853 1.466274603222782 1.7278738998937395 1.8688238302499847 0.7994172350312442 1.5103656439806918 0.878926170627256 1.0661446504604577 1.8343753105342044 1.0 13.288127012727452 -4.760291957584878 5.773238557408626 1.3443441213793046 4.901451156479863 0.8819001013372526 0.37411968590045386 0.04556089520499618 5.339302064683012 0.09494554634299986 0.6443817356367849 1.7366329722540428e-05 4.760291957584878 3.5571070351005583 GSSGPQPAKPCSGATPTPLLLVGDRSPVPS(ph)PGSSSPQLQVK ddPTM_PC-9_AZD4547_30min_R2 1 GSSGPQPAKPCSGATPTPLLLVGDRSPVPSPGSSSPQLQVK 41 2 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 GSSGPQPAKPCSGAT(0.001)PT(0.017)PLLLVGDRS(0.047)PVPS(0.311)PGS(0.208)S(0.208)S(0.208)PQLQVK 50.443999999999996 0.00048074 8290900.0 11913.0 5615.9 22001.0 51760.0 45065.0 27543.0 16418.0 25421.0 16636.0 29862.0 True False 15701.086194206666 7431.129850089928 21709.252364801978 39827.53168402831 38808.50262852279 25820.731855920552 17879.170194119626 21492.76856646637 17515.34499693287 28816.540469285403 0.5448636768505204 0.25787723748485786 0.7533608133127969 1.3821066316575774 1.3467439878804148 0.8960385749095043 0.6204481836803568 0.7458483293431701 0.6078226154732868 1.0 14.814609524659941 -5.46586011959873 5.959212380400703 0.9433389202982535 0.41762530648572155 0.41007980015604584 0.25679779304791217 0.23586971283792016 17.947675497943578 0.07735389060350778 0.16087701638968985 3.4208960722490564e-06 5.46586011959873 -0.525713613812532 GSSGPQPAKPCSGATPTPLLLVGDRSPVPS(ph)PGSSSPQLQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSSGPQPAKPCSGATPTPLLLVGDRSPVPSPGSSSPQLQVK 41 2 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 GSSGPQPAKPCSGATPT(0.001)PLLLVGDRS(0.008)PVPS(0.562)PGS(0.143)S(0.143)S(0.143)PQLQVK 79.63600000000001 1.31e-10 3620700.0 8735.7 3864.4 8053.5 19169.0 19443.0 25175.0 15893.0 22435.0 22713.0 18001.0 True False 10214.481472060299 4248.032093070124 8245.525983068828 18095.023076736503 15633.28372274334 23854.77868194537 14387.499984644273 21846.10502184739 23045.134656225586 21264.438804162408 0.48035509265642434 0.19977165314320885 0.38776127877190003 0.8509522985010304 0.7351844018419711 1.1218155767776912 0.6765990918992884 1.027353941622533 1.0837405524059547 1.0 14.376155160441392 -5.786497830911456 2.8975089657337256 0.9311734983205116 0.32142734781295296 0.7607752104280808 0.14763602959542663 0.11894029991410844 2.040656970783992 0.04244089797817608 0.07340611899323758 1.6349413168417417e-06 5.786497830911456 -0.6097461505075585 down GSSHS(ph)PDHPGCLMEN ddPTM_PC-9_AZD4547_30min_R2 2 GSSHSPDHPGCLMEN 15 0 O95149 O95149 SNUPN Snurportin-1 1 GSS(0.015)HS(0.985)PDHPGCLMEN;GSS(0.001)HS(0.998)PDHPGCLMEN 94.023 0.0027414 5276600.0 5730.5 5513.6 17758.4 32186.0 24261.0 16149.4 11968.8 22891.0 14831.3 19704.1 True False 7552.679798195354 7295.763375675465 17522.91201286757 24766.01496874295 20892.778925343206 15139.575465054764 13034.000013362096 19353.721932850065 15615.252239300948 19014.265456461268 0.3972112315087547 0.38369945935493815 0.9215666023487161 1.3024965400557806 1.098794953356644 0.7962219471333909 0.6854853290655513 1.0178527262683947 0.8212387838518739 1.0 14.21479458658056 -5.273022855013802 6.1880893569736255 0.9595583499090711 0.38697334631801295 0.6596906655151391 0.16241297655673864 0.09141700281713452 16.377073543844762 0.04707462796852423 0.10845380438587628 5.333068291497458e-06 5.273022855013802 -0.5725850035910581 GSSNSYAIK ddPTM_PC-9_Lapatinib_30min_R1 2 GSSNSYAIK 9 0 M0R0F0;M0R0R2;P46782;M0QZN2 M0R0F0 RPS5 40S ribosomal protein S5;40S ribosomal protein S5, N-terminally processed 0 ; 114.86 0.0092785 16666900.0 51176.0 61104.0 56884.0 53007.0 51246.0 52928.0 63120.0 49194.0 45257.0 53521.0 False True 50446.220855471 60962.51744221854 52207.217098589914 56905.311606168376 48231.81103351247 50664.39282119419 66388.04475146807 51479.73283152642 40159.6800826624 62772.033537750256 0.80364165397212 0.9711732121209121 0.8316954885202691 0.9065392404715754 0.7683646413096767 0.8071172776444355 1.0576054495915477 0.8201061831232088 0.6397702578571222 1.0 15.937834326200354 GSSPQNT(ph)TTPKPSVEGQQPAAAAACEPVDHAQSESILK ddPTM_PC-9_AZD4547_30min_R2 1 GSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILK 38 1 Q27J81-2;Q27J81 Q27J81-2 INF2 Inverted formin-2 1 GS(0.053)S(0.171)PQNT(0.303)T(0.087)T(0.303)PKPS(0.083)VEGQQPAAAAACEPVDHAQSESILK 88.348 3.8008e-14 36388000.0 41649.0 43244.0 79228.0 118630.0 95677.0 82932.0 60225.0 88718.0 62547.0 78407.0 True False 54892.5156469834 57221.77731748941 78177.38495334443 91281.68631522942 82393.90005523537 77746.24892986233 65584.9083287157 75008.67163682645 65853.10672776871 75661.99479523333 0.7254965428223364 0.7562816374634409 1.033245094382174 1.2064403874398 1.0889734043917403 1.0275469096508714 0.86681442256724 0.9913652401027094 0.8703591136605537 1.0 16.207281192458723 -5.2463192065634585 7.731641807911604 1.0156417238724096 0.7395483244683647 0.5724983962272304 0.09315230271519656 0.13561994977836103 49.251495683848084 0.026758984933448807 0.06681641846093574 5.671276132311759e-06 5.2463192065634585 -0.27609339940404487 GSSPQNTTT(ph)PKPSVEGQQPAAAAACEPVDHAQSESILK ddPTM_PC-9_Lapatinib_30min_R1 1 GSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILK 38 1 Q27J81-2;Q27J81 Q27J81-2 INF2 Inverted formin-2 1 GS(0.101)S(0.321)PQNT(0.101)T(0.101)T(0.372)PKPS(0.003)VEGQQPAAAAACEPVDHAQSESILK 78.9 1.5232e-09 28986000.0 10141.0 10823.0 12912.0 7821.4 9495.6 12293.0 8474.1 7722.6 10192.0 6632.7 True False 9996.387480368368 10797.940008463136 11850.425201761369 8396.611847425536 8937.087477067886 11767.257046382629 8912.847433910252 8081.420188737362 9044.069633482002 7779.153357482788 1.2850225494979883 1.3880610796901913 1.5233566761301105 1.0793734821217804 1.1488509181363904 1.5126655184222166 1.145734892260089 1.0388560062212713 1.1626033345624287 1.0 12.92539743300639 -7.606250578537969 0.425063626438298 0.9876472851780767 1.3747027742528135 0.36646312163291683 0.14333675724666975 1.2190458921424172 0.5534956232453973 0.1682962372185371 0.1492907129437458 2.4759930508957665e-08 7.606250578537969 0.38705548907473686 GSSPSIRPIQGSQGS(ph)SSPVEK ddPTM_PC-9_AZD4547_30min_R2 1 GSSPSIRPIQGSQGSSSPVEK 21 1 Q92560;F8W6N3;H0Y8E8 Q92560 BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1;Ubiquitin carboxyl-terminal hydrolase 1 GSSPSIRPIQGS(0.001)QGS(0.376)S(0.376)S(0.246)PVEK 83.221 0.00026051 9065200.0 14262.0 17472.0 16240.0 14124.0 13718.0 16015.0 17554.0 15266.0 18777.0 15136.0 True False 18797.019331971416 23119.482316417892 16024.6469889725 10867.930013624735 11813.49248991624 15013.579518301107 19116.271993396014 12906.990477781197 19769.513885994755 14606.093247039833 1.2869299828536247 1.5828655839304215 1.0971206823029258 0.7440682343875424 0.8088057696270315 1.0278983753129098 1.3087874813663978 0.8836716471324058 1.353511411410534 1.0 13.83428272560116 -5.389632455820733 5.562955390492701 1.010659237751407 1.4301807745532151 0.4140035045654281 0.19495142559375098 0.20675942393095167 8.394853576290362 0.05269974401185222 0.11211193879481962 4.077251903748689e-06 5.389632455820733 0.41952153680180815 GSSPSIRPIQGSQGS(ph)SSPVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSSPSIRPIQGSQGSSSPVEK 21 1 Q92560;F8W6N3;H0Y8E8 Q92560 BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1;Ubiquitin carboxyl-terminal hydrolase 1 GSSPSIRPIQGS(0.009)QGS(0.419)S(0.419)S(0.154)PVEK 78.67399999999999 0.00050662 7266200.0 10551.0 11250.0 11825.0 7587.3 11425.0 6517.0 10370.0 7259.4 8582.5 8014.8 True False 12337.075908250985 12366.825651340143 12106.952846562228 7162.2081793584875 9186.353265048732 6175.237047477181 9387.678527701575 7068.8484419700935 8708.002826005204 9467.819794878114 1.3030535197686246 1.306195715515237 1.278747706321135 0.7564791403437027 0.9702712413282676 0.652234324402525 0.991535404252213 0.7466183973837554 0.9197474196452329 1.0 13.208816531555291 -5.752244919127148 24.982034812073525 0.8529715482502113 1.2970188446528208 0.7660063372151396 0.1097302352500683 79.91996109700634 217146.3252550209 0.027312040271684792 0.04647268094135401 1.7691109918751429e-06 5.752244919127148 0.44404729640260954 GSSPSIRPIQGSQGS(ph)SSPVEK ddPTM_PC-9_Lapatinib_30min_R1 1 GSSPSIRPIQGSQGSSSPVEK 21 1 Q92560;F8W6N3;H0Y8E8 Q92560 BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1;Ubiquitin carboxyl-terminal hydrolase 1 GSSPSIRPIQGS(0.004)QGS(0.417)S(0.163)S(0.417)PVEK 59.792 0.005164 8031100.0 12303.0 18155.0 16028.0 16615.0 21340.0 19340.0 17805.0 19063.0 16894.0 16448.0 True False 12127.556963906127 18112.963212939867 14710.239709869207 17836.922526015198 20084.823156054237 18512.873283741967 18726.855779465914 19948.73657290295 14991.21981829327 19291.014884417647 0.6286635014574679 0.938932623372275 0.7625435881940784 0.9246233354173089 1.0411491192346645 0.9596630034584532 0.9707553434419133 1.0340947167593852 0.7771089239271934 1.0 14.235641423931872 -4.024708094693768 0.7661859348316604 0.960545522454466 5.663348953668035e-17 0.48653618103715046 0.09234271205648567 6.587133335601553 1.2741559872205732 0.03403177044309619 7.1112832943751965 9.446956276446157e-05 4.024708094693768 -0.9605455224544659 GSSPSIRPIQGSQGSSS(ph)PVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSSPSIRPIQGSQGSSSPVEK 21 1 Q92560;F8W6N3;H0Y8E8 Q92560 BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1;Ubiquitin carboxyl-terminal hydrolase 1 GSSPSIRPIQGS(0.188)QGS(0.045)S(0.188)S(0.578)PVEK 65.954 0.0019564 8316700.0 26398.0 41718.0 29691.0 32031.0 37281.0 26810.0 34947.0 23121.0 23200.0 20457.0 True False 30866.660015734036 45859.487335342965 30398.94604374455 30236.40691590312 29976.05567389775 25404.036403692382 31636.567165630368 22514.09824872448 23539.256109912098 24165.69216247711 1.277292610044158 1.8977104825720883 1.25793814798924 1.2512121197526556 1.2404385304734862 1.051243897045833 1.3091521216492834 0.931655426931362 0.9740774628612666 1.0 14.560672697098958 -5.955343576249906 0.5912245980785721 1.0047342019147638 1.643691967148622 0.5074595184032737 0.18486377326028605 0.9706027680832182 0.6140627434904588 0.12029687744897702 0.36069590042156874 1.1082976790381662e-06 5.955343576249906 0.6389577652338583 GSSPSIRPIQGSQGSSS(ph)PVEK ddPTM_PC-9_Lapatinib_30min_R1 1 GSSPSIRPIQGSQGSSSPVEK 21 1 Q92560;F8W6N3;H0Y8E8 Q92560 BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1;Ubiquitin carboxyl-terminal hydrolase 1 GSSPSIRPIQGS(0.004)QGS(0.148)S(0.23)S(0.618)PVEK 92.71600000000001 0.00019071 12731000.0 15483.0 17429.0 17073.0 16442.0 26558.0 18114.0 20179.0 20383.0 17975.0 18851.0 True False 15262.20958076554 17388.64422133456 15669.323843685857 17651.199528904115 24995.910655036958 17339.306445796385 21223.76988339471 21330.068591799863 15950.466214858614 22109.37023262141 0.690305034480214 0.7864830177604234 0.7087186870916139 0.7983583133842745 1.1305573334764905 0.7842514853821116 0.9599445692071302 0.9647524270197564 0.7214346698724325 1.0 14.43237031129727 -6.012703468885258 24.694697075332186 0.9236675314979758 0.7375066498417799 0.41076747978382266 0.10836254710819923 517.3394234899389 1005676.3818459702 0.030106648254478435 0.04093758413927671 9.711728462029375e-07 6.012703468885258 -0.18616088165619582 GSSQPNLS(ph)TSHSEQEYGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSSQPNLSTSHSEQEYGK 18 0 F6PQP6;E9PBC1;I3L2B2;O95208-2;O95208;O95208-3 F6PQP6 EPN2 Epsin-2 1 GS(0.033)S(0.112)QPNLS(0.582)T(0.224)S(0.049)HSEQEYGK 97.214 0.00044576 14110000.0 17765.0 21849.0 55831.0 62431.0 67174.0 56792.0 54585.0 42018.0 51963.0 38495.0 True False 20772.263625256262 24018.024324989423 57162.22278024661 58933.19347403294 54011.73691259377 53813.72754339785 49414.313638822634 40915.07202175103 52722.860570662204 45473.83877374765 0.456795911350423 0.528172350799097 1.25703534871234 1.2959801737269532 1.1877540662737078 1.1833997083717698 1.086653666620946 0.8997496830061238 1.1594108171289788 1.0 15.47274917703598 -5.252180846744703 22.93540910815963 1.1379817033717168 0.4924837061362837 0.8401982092265516 0.11185343446211592 82.34465789919055 203981.53380625148 0.03133882668752283 0.08009144506116309 5.595245585478043e-06 5.252180846744703 -0.6454979972354331 GSSQPNLSTS(ph)HSEQEYGK ddPTM_PC-9_AZD4547_30min_R2 1 GSSQPNLSTSHSEQEYGK 18 0 F6PQP6;E9PBC1;I3L2B2;O95208-2;O95208;O95208-3 F6PQP6 EPN2 Epsin-2 1 GS(0.001)S(0.001)QPNLS(0.091)T(0.243)S(0.659)HS(0.006)EQEYGK 67.252 0.007457500000000001 44651000.0 27390.0 24037.0 24897.0 49548.0 50160.0 42897.0 26334.0 44042.0 35780.0 35249.0 True False 36099.4502526081 31806.490180845754 24566.849512589175 38125.474108968985 43196.1498246245 40214.6438087145 28677.67498428226 37236.320884477864 37671.25775368225 34014.94323896058 1.0612820959013076 0.9350740337092414 0.7222369692050641 1.1208448546020273 1.2699168574577484 1.1822640280831869 0.8430904847559754 1.0947047779232373 1.107491418963585 1.0 15.053881061223212 -5.807036191960084 24.99917328820533 1.0935382181468787 0.9090842367704325 0.2898504055367729 0.13044101350147205 162.29699434247752 88981.11739166734 0.03903274810720419 0.057895182548402674 1.5594225428286175e-06 5.807036191960084 -0.1844539813764462 GSSS(ph)ASIVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSSSASIVK 9 0 Q14126 Q14126 DSG2 Desmoglein-2 1 GS(0.001)S(0.01)S(0.495)AS(0.495)IVK 75.566 0.025786 35417000.0 67105.0 62740.0 49728.0 42004.0 81783.0 44459.0 36916.0 42745.0 44650.0 31367.0 True False 78464.55111583587 68968.41256578508 50913.704114490225 39650.6520588054 65758.20823417783 42127.491774403556 33419.04923130486 41622.98904207119 45302.92178049897 37053.588798964636 2.117596531379124 1.8613153219779948 1.3740559488238524 1.0700893852396107 1.7746785227998014 1.1369341847821417 0.9019112672896793 1.1233186957381638 1.2226324965792472 1.0 15.177325660048908 -1.5228787452860284 0.4124655861030845 1.0756552088382418 20.5890383664733 0.698198884489083 0.21597315985107976 44.08797055126148 0.572712584927655 0.15675187845911592 705.8745514105012 0.02999999999960689 1.5228787452860284 19.513383157635058 GSSSANPVNS(ph)VR ddPTM_PC-9_AZD4547_30min_R2 2 GSSSANPVNSVR 12 0 Q5JR89;Q99661-2;Q99661 Q5JR89 KIF2C Kinesin-like protein KIF2C 1 GSSSANPVNS(1)VR;GSSSANPVNS(1)VR 124.81 0.00031141 9598500.0 11918.8 12999.1 12576.8 19245.5 22445.0 16383.3 13978.5 25726.0 15612.5 18556.7 True False 15708.730473559162 17200.804863744732 12410.02341446487 14808.747315010965 19328.89917890146 15358.849661079154 15222.559420057327 21750.63782466912 16437.744876449542 17907.0355812199 0.8772379103347389 0.9605612713353944 0.6930250045116316 0.8269792757066791 1.0794025114448729 0.8576991759142327 0.8500881874620312 1.2146420174358852 0.9179489704978704 1.0 14.128238905804036 -7.138765283957008 0.8731814101659496 1.0328604857070203 0.8557971410436793 0.1992885989399923 0.12348540704694949 0.9616445392879002 1.472216423770626 0.09429469930957098 0.061196555988964924 7.26498490121927e-08 7.138765283957008 -0.17706334466334095 GSSSANPVNS(ph)VR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSSSANPVNSVR 12 0 Q5JR89;Q99661-2;Q99661 Q5JR89 KIF2C Kinesin-like protein KIF2C 1 GSSSANPVNS(1)VR 78.40100000000001 0.016513999999999997 5032400.0 10014.0 5715.5 6697.4 7286.7 12398.0 6791.1 2088.2 9410.3 7405.0 5960.2 True False 11709.172414484448 6282.897067576411 6857.0914160309385 6878.449822800138 9968.700899787682 6434.962760951706 1890.3905787412177 9163.28959603702 7513.284116116347 7040.737079082755 1.6630605976284918 0.8923635404938209 0.973916699205058 0.9769502461944283 1.4158604117463185 0.9139615197490135 0.26849327811961016 1.3014673738151836 1.0671161316955686 1.0 12.781510753961312 -6.963290189300025 24.816379347549102 0.8853678241653685 1.1469755571968645 0.14402060286689444 0.32591012742314357 343.2111052947309 232014.7339675197 0.1170705289508651 0.10324622595798727 1.0882027290073865e-07 6.963290189300025 0.261607733031496 GSSSAS(ph)IVK ddPTM_PC-9_AZD4547_30min_R2 1 GSSSASIVK 9 0 Q14126 Q14126 DSG2 Desmoglein-2 1 GSS(0.003)S(0.059)AS(0.938)IVK 79.20100000000001 0.02049 27492000.0 74026.0 78999.0 98421.0 117980.0 100400.0 70865.0 84479.0 92427.0 80325.0 88649.0 True False 97564.72816354773 104533.88184035581 97115.8732328609 90781.53377282967 86461.19303014966 66433.80034744977 91997.46734249183 78144.53091116747 84570.81551326247 85545.42549265572 1.140501991797608 1.221969278174089 1.135255014205272 1.0612085129043338 1.0107050439251433 0.7765909160525862 1.0754224064311895 0.913485793788896 0.9886071058296749 1.0 16.384403088787657 -5.984967164995653 1.8475399732475049 0.951515545082575 1.178992893218613 0.6010357554121091 0.07576993320826997 0.223693195632813 1.538953189558239 0.024166693339978465 0.03979506998372199 1.0352204319667549e-06 5.984967164995653 0.22747734813603793 GSSSAS(ph)IVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSSSASIVK 9 0 Q14126 Q14126 DSG2 Desmoglein-2 1 GSS(0.002)S(0.032)AS(0.967)IVK 72.2 0.032925 29963000.0 75258.0 86953.0 62446.0 57789.0 100240.0 53289.0 42775.0 53988.0 41422.0 35136.0 True False 87997.69298674547 95585.11918764244 63934.94946777378 54551.26968446585 80598.69157886071 50494.43103007694 38723.042335818245 52570.87220501435 42027.71838727497 41505.878663577045 2.12012601154657 2.3029296635881593 1.5403829897445125 1.3143022492458791 1.9418620728920761 1.2165609464470315 0.9329532004293927 1.2665885869113584 1.01257267019758 1.0 15.341028065843997 -4.415709744815824 0.3260231095264331 0.9544130788415978 3.6565014035381758 0.7243074271413095 0.24583914942785667 4.874812271827294 0.34869689637947726 0.2589283129693325 5.4605315213171215 3.8396377705672114e-05 4.415709744815824 2.702088324696578 up GSSSAS(ph)IVK ddPTM_PC-9_Lapatinib_30min_R1 4 GSSSASIVK 9 0 Q14126 Q14126 DSG2 Desmoglein-2 1 GSSS(0.005)AS(0.995)IVK;GS(0.008)S(0.006)S(0.016)AS(0.97)IVK;GS(0.003)S(0.057)S(0.042)AS(0.898)IVK;GSS(0.008)S(0.191)AS(0.8)IVK 112.83 0.0021416 101733000.0 476487.0 546092.0 288123.0 215724.0 290327.0 188821.0 158623.0 159097.0 295728.0 122993.0 True False 469692.2080029864 544827.5575257938 264434.63912694255 231589.0625941679 273250.53666484356 180745.56599324915 166835.7227917001 166489.22743215333 262419.9984861036 144252.17617212894 3.25604937455173 3.7769104909424605 1.8331414204206242 1.6054458846972555 1.8942559059822246 1.252983287944124 1.1565560202892422 1.154154008973078 1.8191753181800938 1.0 17.138233557807098 -5.3584860527467635 3.782027000934028 1.4366594871118576 3.525751943427584 0.8778821742513055 0.3084464113242083 0.0714921418403404 1.8490689762277597 0.08543948494293424 0.19825189401715104 4.380401784897738e-06 5.3584860527467635 2.0890924563157265 GSSSQGPSQTS(ph)TPTDVTAIHL ddPTM_PC-9_AZD4547_30min_R2 1 GSSSQGPSQTSTPTDVTAIHL 21 0 Q5T8J1;P30281-4;P30281-2;P30281-3;P30281 Q5T8J1 CCND3 G1/S-specific cyclin-D3 1 GSSSQGPSQT(0.067)S(0.511)T(0.372)PT(0.05)DVTAIHL 184.15 5.919e-15 3207400.0 3868.0 4718.4 6090.2 12420.0 9106.7 7374.2 6199.2 8528.0 6694.6 8537.7 True False 5097.943540601979 6243.530526659009 6009.439968734013 9556.760887087168 7842.391898084287 6913.090108264504 6750.916790558312 7210.193553944585 7048.46288870322 8238.79772167363 0.6187727521445182 0.7578205871269647 0.7294073931351788 1.1599703269745778 0.9518854768643576 0.8390896756790599 0.819405575743026 0.875151180733189 0.855520808595771 1.0 13.00821810659347 -5.556499372851639 24.999578425569442 0.9183838906583347 0.7021256463459499 0.5238691467302723 0.0990466035993248 154.24356154314043 114691.52858975608 0.02844841527949724 0.04927442606366541 2.776518855569283e-06 5.556499372851639 -0.21625824431238483 GSSSQGPSQTST(ph)PTDVTAIHL ddPTM_PC-9_AZD4547_30min_R2 2 GSSSQGPSQTSTPTDVTAIHL 21 0 Q5T8J1;P30281-4;P30281-2;P30281-3;P30281 Q5T8J1 CCND3 G1/S-specific cyclin-D3 1 GSSSQGPS(0.002)QT(0.009)S(0.159)T(0.829)PT(0.001)DVTAIHL;GSSSQGPSQT(0.018)S(0.28)T(0.614)PT(0.087)DVTAIHL 203.17 5.3122e-24 8741800.0 10055.0 8817.1 15591.400000000001 26662.0 23259.0 20064.3 12325.5 23078.0 16019.8 17975.6 True False 13252.280843007466 11667.055147212004 15384.64784876022 20515.48782379373 20029.889329564216 18809.676149175724 13422.445622342631 19511.825379682577 16866.573922930118 17346.27971534681 0.7639840392567144 0.6725969682646007 0.8869133959109935 1.1827024676445763 1.1547080790956652 1.0843637055232196 0.7737939110060219 1.124842081407222 0.9723453212856772 1.0 14.082338658391105 -5.508450510371938 4.903617426272267 1.042770248988473 0.7273774659406448 0.5745078099256564 0.11163821574717067 0.13313916300758433 8.871257416873917 0.03160999458114543 0.06267968840307585 3.1013407788315273e-06 5.508450510371938 -0.31539278304782814 GSSSQGPSQTST(ph)PTDVTAIHL ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSSSQGPSQTSTPTDVTAIHL 21 0 Q5T8J1;P30281-4;P30281-2;P30281-3;P30281 Q5T8J1 CCND3 G1/S-specific cyclin-D3 1 GSSSQGPSQT(0.007)S(0.095)T(0.6)PT(0.298)DVTAIHL;GSSSQGPS(0.001)QT(0.028)S(0.28)T(0.449)PT(0.239)DVT(0.003)AIHL 149.72 0.00020227 3660000.0 4424.700000000001 4435.39 8906.599999999999 9444.1 13877.6 15130.5 13069.0 9734.5 13454.2 10565.5 True False 5173.714318191471 4875.706206728673 9118.967122468597 8914.977695185315 11158.383901185152 14337.029944277041 11831.009708633743 9478.979689555314 13650.942222154292 12480.941513548025 0.41452916933994277 0.390652115582475 0.7306313480092816 0.714287274362125 0.8940338266205927 1.1487138152770155 0.9479260595677992 0.7594763327162385 1.0937429846407207 1.0 13.607439149141623 -5.58680504810874 1.057747578025931 0.9736841505110092 0.34058066651067687 0.7977390690560806 0.1108648915796839 0.30525803134371376 0.5979476024298715 0.041921342424171046 0.16171631090506208 2.589375007446208e-06 5.58680504810874 -0.6331034840003323 down GSSSQGPSQTST(ph)PTDVTAIHL ddPTM_PC-9_Lapatinib_30min_R1 2 GSSSQGPSQTSTPTDVTAIHL 21 0 Q5T8J1;P30281-4;P30281-2;P30281-3;P30281 Q5T8J1 CCND3 G1/S-specific cyclin-D3 1 GSSSQGPSQT(0.001)S(0.034)T(0.893)PT(0.071)DVTAIHL;GSSSQGPSQT(0.001)S(0.019)T(0.975)PT(0.005)DVTAIHL 206.63 3.4266e-24 6495500.0 16214.5 12102.4 16718.8 14921.8 22230.0 23195.2 16791.1 19320.1 27935.2 22853.9 True False 15983.27825662488 12074.377636369245 15344.244800434319 16019.198949665575 20922.47510586156 22203.195366652115 17660.46099851672 20217.782377492655 24788.843605302834 26804.166164092418 0.5962982828406918 0.4504664522093736 0.5724574570422519 0.5976383988816383 0.780568027290096 0.8283486690362378 0.6588700014169867 0.7542776094477783 0.9248130851580317 1.0 14.710169635349883 -6.026282878896283 0.19004370170015142 1.0676406880879248 0.20858222297240575 0.7716076306555768 0.07783065769609517 4.584225108055862 0.27472237915660314 0.2616957816400287 1.0182677906505628 9.412762939229112e-07 6.026282878896283 -0.8590584651155191 GSSSQGPSQTSTPT(ph)DVTAIHL ddPTM_PC-9_AZD4547_30min_R2 1 GSSSQGPSQTSTPTDVTAIHL 21 0 Q5T8J1;P30281-4;P30281-2;P30281-3;P30281 Q5T8J1 CCND3 G1/S-specific cyclin-D3 1 GSSSQGPSQTST(0.003)PT(0.996)DVTAIHL 121.56 4.048e-06 5388200.0 4428.3 3388.3 7009.6 8629.4 6942.8 5085.5 5550.7 9869.5 4919.1 5556.7 True False 5836.407285637987 4483.5017131821605 6916.6481240087205 6640.0251529009665 5978.912061451418 4767.502881069017 6044.70154686928 8344.39555354785 5179.113583458316 5362.161624327848 1.088443000143545 0.8361369961026066 1.289899225086437 1.2383112666308898 1.1150189942663058 0.8891009288938821 1.1272882039669943 1.55616263331 0.9658630131477103 1.0 12.388598989827788 -7.534677337860836 24.999541376531543 1.224952714599324 1.0777702453369815 0.028762760957576572 0.19841558560756897 561.0391721417454 1188746.6293305738 0.0922560986508888 0.053314800672122284 2.9195953423033692e-08 7.534677337860836 -0.14718246926234246 GSSSQGPSQTSTPT(ph)DVTAIHL ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSSSQGPSQTSTPTDVTAIHL 21 0 Q5T8J1;P30281-4;P30281-2;P30281-3;P30281 Q5T8J1 CCND3 G1/S-specific cyclin-D3 1 GSSSQGPSQTS(0.004)T(0.446)PT(0.55)DVTAIHL 160.87 1.1272e-05 4599300.0 4876.5 3536.6 6670.3 6243.3 7969.3 10364.0 9046.1 8971.5 7065.8 7679.4 True False 5701.995134734717 3887.6902754248486 6829.345249253619 5893.508142051698 6407.772873098719 9820.493595220723 8189.187919907546 8736.00763108999 7169.1239578196955 9071.614429903044 0.6285535147899423 0.428555501941279 0.7528257844316923 0.6496647523537535 0.7063541911543968 1.0825519174237748 0.9027266296628824 0.9630047329054481 0.7902809376672679 1.0 13.147143607494261 -6.597503794512783 5.389927706110165 0.9416296861587794 0.6186452885154856 0.7088741557019571 0.10196160187863772 0.11679725575305676 6.05052083945138 0.03451816760448548 0.034592822044132505 2.5263656367025023e-07 6.597503794512783 -0.3229843976432938 GSSSQGPSQTSTPT(ph)DVTAIHL ddPTM_PC-9_Lapatinib_30min_R1 2 GSSSQGPSQTSTPTDVTAIHL 21 0 Q5T8J1;P30281-4;P30281-2;P30281-3;P30281 Q5T8J1 CCND3 G1/S-specific cyclin-D3 1 GSSSQGPSQTS(0.01)T(0.21)PT(0.779)DVTAIHL;GSSSQGPSQTS(0.001)T(0.036)PT(0.964)DVTAIHL 191.19 1.2924000000000001e-52 3184100.0 12741.4 10272.2 13440.1 11606.5 13724.0 17804.800000000003 12534.1 13511.900000000001 16117.800000000001 14181.5 True False 12559.705299513404 10248.415352022084 12335.106858286312 12460.080728148992 12916.781302422143 17043.33020901599 13183.054368177682 14139.712201616085 14302.44363604162 16632.753379339054 0.7551188316851299 0.6161586791007498 0.7416154485648052 0.7491291696555009 0.7765870753826704 1.024684838421698 0.7925960343134448 0.8501125387441993 0.8598963328469652 1.0 14.021739391103953 -6.5342736856107155 24.540593079808954 0.890325027210164 0.7168472816914337 0.5931225513838831 0.07445371237135083 134.02756827785507 288644.6084406579 0.02449047336508668 0.02451118989389305 2.922310203125812e-07 6.5342736856107155 -0.1734777455187303 GSSSS(ph)SPEHSASSDSTK ddPTM_PC-9_AZD4547_30min_R2 2 GSSSSSPEHSASSDSTK 17 0 A0A075B784;Q9P275 A0A075B784 USP36 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 36 1 GSSS(0.001)S(0.499)S(0.499)PEHSASSDSTK;GS(0.003)S(0.012)S(0.093)S(0.593)S(0.294)PEHS(0.005)ASSDSTK 249.36 1.3216e-47 8263500.0 6854.7 5952.2 30732.0 36340.0 35626.0 34203.0 19423.4 43075.0 26761.0 33578.0 True False 9034.35201338273 7876.132248384987 30324.473600067908 27962.374447403192 30679.944849523 32064.281003087908 21152.04497188835 36418.74851502849 28175.5318263357 32402.444440347765 0.2788169895643147 0.2430721627463874 0.9358699358591492 0.862971140923684 0.946840443041393 0.9895636442527536 0.6527916438782522 1.1239506507626196 0.869549576057642 1.0 14.983815033676061 -5.261471064258374 24.99997888653014 0.9185974639484661 0.2609445159733661 0.8417285620511996 0.11476937047482803 0.9030297332308377 713201.2427980087 0.02839686914073509 0.06594609365233108 5.47682590198244e-06 5.261471064258374 -0.6576529479751 GSSSS(ph)SPEHSASSDSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSSSSSPEHSASSDSTK 17 0 A0A075B784;Q9P275 A0A075B784 USP36 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 36 1 GS(0.004)S(0.07)S(0.045)S(0.783)S(0.097)PEHS(0.001)ASSDSTK 172.42 9.0351e-06 4432300.0 4974.7 7103.5 19782.0 15972.0 18812.0 14274.0 12902.0 11150.0 12237.0 7331.5 True False 5816.818455196306 7808.688534603974 20253.67790365278 15077.140621922652 15125.923643071936 13525.44631205912 11679.829157609045 10857.324314401541 12415.942974870455 8660.642913877937 0.6716381812573468 0.9016291991546287 2.338588267067102 1.7408800676636638 1.7465127928128685 1.5617138873588419 1.3486099442909858 1.2536395302713164 1.4336052298120932 1.0 13.080258410565069 -7.435768163065264 3.5113865308582355 1.2614286022015269 1.5270591277459087 0.06269715216720229 0.44444503494092363 0.8386434639106195 19.51347712157686 0.2260972123133866 0.14061236314826128 3.666332401394417e-08 7.435768163065264 0.2656305255443818 GSSSSS(ph)PEHSASSDSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSSSSSPEHSASSDSTK 17 0 A0A075B784;Q9P275 A0A075B784 USP36 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 36 1 GS(0.003)S(0.034)S(0.173)S(0.136)S(0.553)PEHS(0.086)AS(0.011)S(0.004)DSTK 88.427 0.0027274 3602400.0 3402.9 7158.6 14348.0 13166.0 15988.0 13850.0 10870.0 8862.3 8585.2 7728.5 True False 3978.94375966139 7869.258498460763 14690.110735093016 12428.351704747916 12855.266170818315 13123.681618468449 9840.314908015062 8629.674015383027 8710.742308397299 9129.61587122766 0.4358281679956751 0.861948477291475 1.609061207206918 1.3613225222231258 1.4080840149400138 1.4374845342429186 1.0778454479149773 0.9452395519267992 0.9541192566326414 1.0 13.156338444725545 -7.515268714867086 13.58758294400309 0.9720779683759021 1.2123741515487105 0.08518929907422834 0.3156212256588401 2.493414174295016 4460.618408897132 0.1542622857576297 0.09537934539957858 3.05303149949657e-08 7.515268714867086 0.24029618317280843 GSST(ph)PTKGIENK ddPTM_PC-9_AZD4547_30min_R2 1 GSSTPTKGIENK 12 1 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9;H0YBE9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 GS(0.002)S(0.141)T(0.856)PT(0.002)KGIENK 164.93 0.0082552 5400800.0 24404.0 10551.0 25560.0 60718.0 52011.0 32799.0 19943.0 27013.0 17860.0 34317.0 True False 32163.96436526646 13961.404413949464 25221.057699392688 46720.40318374866 44790.17042521025 30748.073345036417 21717.888365289775 22838.761546986985 18804.04313808734 33115.57227528185 0.9712640354783877 0.42159635043874955 0.7616071825585877 1.4108288026966016 1.3525410357665044 0.9285079867995342 0.6558210193305479 0.6896683335904272 0.567830837461416 1.0 15.015222169430192 -10.594613213833426 4.2555083147608395 1.0000145653870944 0.8676343371688331 0.0179371414705517 0.3035210060339783 160670559.871704 1.503592002604275 23368.79671199946 0.08221254881378456 2.5432367243515335e-11 10.594613213833426 -0.13238022821826134 GSST(ph)PTKGIENK ddPTM_PC-9_Lapatinib_30min_R1 1 GSSTPTKGIENK 12 1 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9;H0YBE9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 GS(0.007)S(0.14)T(0.85)PT(0.002)KGIENK 130.61 0.0014508 5349900.0 66757.0 24565.0 34728.0 30694.0 20521.0 23373.0 11760.0 13829.0 27827.0 14775.0 True False 65805.03293826553 24508.121251769106 31872.797893956682 32951.33915218241 19313.995125838293 22373.39127512416 12368.875257878077 14471.545825246549 24692.830228699357 17328.839063550007 3.797428823531623 1.4142967778678384 1.8392921636048238 1.90153183553382 1.1145579374941466 1.2911073380665767 0.7137740279379209 0.8351134067420839 1.424955828728249 1.0 14.08088738469025 -2.16448658314588 0.8095006259839794 1.1344262960863116 199.99999994170022 0.7929646620405425 0.3822881806355242 75.47402105281247 0.8088621187025301 0.14070214485078267 26828.365914747064 0.00684720636145953 2.16448658314588 198.86557364561392 up GSSVES(ph)LPPTSEGK ddPTM_PC-9_Lapatinib_30min_R1 1 GSSVESLPPTSEGK 14 0 O43318-3;O43318;Q9UG54;O43318-4;O43318-2 O43318-3 MAP3K7;DKFZp586F0420 Mitogen-activated protein kinase kinase kinase 7 1 GS(0.002)S(0.029)VES(0.965)LPPT(0.002)S(0.002)EGK 70.438 0.0274 2868400.0 12958.0 9525.1 12225.0 13428.0 11231.0 10539.0 9981.4 14665.0 15359.0 15655.0 True False 12773.216543793835 9503.045216170398 11219.907689864673 14415.539914494851 10570.414660995553 10088.271537608929 10498.188052634705 15346.389437214588 13629.10768255986 18360.945891023715 0.6956731216139793 0.5175683906794932 0.6110746013008977 0.7851196773877706 0.5757009864161307 0.5494418205622443 0.57176727794656 0.8358169305818345 0.7422878844832742 1.0 14.164352762764025 -8.444948286689272 1.0274859747262561 0.9891315385946233 0.6155989727044349 0.6203311848959683 0.08969791962503264 0.3486844836844429 0.8072355437002552 0.08670764403959873 0.028863439019984075 3.58964675567173e-09 8.444948286689272 -0.37353256589018846 GSSYS(ph)SIPK ddPTM_PC-9_Lapatinib_30min_R1 1 GSSYSSIPK 9 0 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 1 GS(0.002)S(0.01)YS(0.494)S(0.494)IPK 70.1 0.038582 7792400.0 111950.0 100770.0 83436.0 105320.0 111460.0 89424.0 74799.0 73637.0 69744.0 85136.0 True False 110353.5724708843 100536.67325629025 76576.21415227394 113065.58413722039 104904.14193879126 85599.54397752548 78671.72622568216 77058.44384508481 61888.69628312089 99851.64416341083 1.1051753167958525 1.0068604688347278 0.7668998822588659 1.1323357275137549 1.050600045875177 0.8572672457695211 0.7878861373272235 0.7717293439753068 0.6198064819226992 1.0 16.607498562920952 -6.942141116164057 3.7440265055227244 0.7793909627166143 1.004501642507243 0.3993010422782466 0.12647247745665763 0.2346448951515248 6.746599447992599 0.04764482327170994 0.040685700091166975 1.142507037400883e-07 6.942141116164057 0.2251106797906287 GST(ph)ESCNTTTEDEDLKVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSTESCNTTTEDEDLKVR 18 1 Q5SWX3;Q13555-5;Q13555-11;Q8WU40;Q13555-10;Q13555-4 Q5SWX3 CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 1 GS(0.168)T(0.647)ES(0.168)CNT(0.015)T(0.001)TEDEDLKVR 79.237 0.0029689 8519800.0 6807.1 7579.2 7084.9 11375.0 14135.0 13604.0 6517.5 9899.8 7767.4 2531.9 True False 7959.407583646606 8331.612886812196 7253.830885632871 10737.695628247575 11365.348218946507 12890.582291526702 5900.115217386212 9639.940739705145 7880.983530522905 2990.9134274906287 2.6611962454307934 2.7856416070867036 2.425289484797567 3.5901057949565875 3.7999589404638887 4.309914881870011 1.9726800392000643 3.2230758172740024 2.634975475413555 1.0 11.546370436664814 -9.054323796511733 0.9583005282399503 0.9928509439751142 3.1445795933695364 0.48448058240671665 0.6493154949217093 1.7936227097804083 2.3805679121938286 0.6863437661393919 0.21652458357683935 8.824217487808956e-10 9.054323796511733 2.151728649394422 GSTAENAEY(ph)LR ddPTM_PC-9_AZD4547_30min_R2 2 GSTAENAEYLR 11 0 P00533;E9PFD7 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 GSTAENAEY(1)LR;GSTAENAEY(1)LR 131.42 0.00023163 67718000.0 38448.0 54866.0 62735.0 61403.0 62374.0 46861.0 40632.0 67389.0 47302.0 50811.0 True False 50673.66423191958 72600.36153689244 61903.0929096792 47247.48701689317 53714.446753611046 43930.77426207361 44248.16928538607 56975.57849516552 49802.28715105307 49032.12235566473 1.0334789072426354 1.480669366303799 1.2625007838871873 0.963602731168226 1.0954950382115238 0.8959590601323062 0.9024322660239494 1.1620051459710692 1.015707351800964 1.0 15.581439589586756 -5.741742483118308 10.395046648197772 1.006721348980739 1.28141201920014 0.45749071971134747 0.1259570799581538 0.297787435084648 150.18715886386792 0.03361394168182669 0.056988598197243376 1.8124144534303633e-06 5.741742483118308 0.27469067021940097 GSTAENAEY(ph)LR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSTAENAEYLR 11 0 P00533;E9PFD7 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 GSTAENAEY(1)LR;GSTAENAEY(1)LR 144.17 0.00024642 18919100.0 22857.8 40607.0 48855.0 25979.0 63596.0 49168.0 55161.0 53024.0 51761.0 52152.0 True False 26727.174077871263 44638.19459768617 50019.888483619274 24523.480855054404 51134.820327705835 46589.543524682806 49935.75074894377 51632.176183571944 52517.90670280865 61606.744764995135 0.43383519417921923 0.7245666812613272 0.8119222769264138 0.39806487014695524 0.8300198382947278 0.7562409554733514 0.8105565541472529 0.8380929130491775 0.8524700810462111 1.0 15.910800686741236 -4.488613600955701 0.12656922570559315 1.1289548385189574 2.831680785150204e-17 0.521444158639329 0.12355030482651519 33.68730160334596 0.6450522889283451 1.0240775492848666 6.604306435318813 3.2462831612769365e-05 4.488613600955701 -1.1289548385189574 GSTAENAEY(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 2 GSTAENAEYLR 11 0 P00533;E9PFD7 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 GSTAENAEY(1)LR;GSTAENAEY(1)LR 170.89 0.0023052 29466200.0 54529.0 51950.0 31276.0 19255.0 41479.0 39722.0 38020.0 45066.0 71022.0 24845.0 True False 53751.40646060608 51829.71296679851 28704.608008851315 20671.076932797037 39039.286770851635 38023.18265650458 39988.48956671124 47159.9308815215 63022.75446518427 29139.425146118436 1.84462823789666 1.778680008507394 0.9850780468356274 0.7093851999187624 1.3397411436598614 1.3048707195093558 1.3723156639566712 1.6184235153933197 2.162800197641487 1.0 14.830684796175465 -7.745072685527381 4.024029274710331 1.6759981918933586 1.3082268262821881 0.06886138248040297 0.4084711666129344 0.47275270338008 16.951036547564524 0.23379542580295545 0.11743120953524336 1.798569872988959e-08 7.745072685527381 -0.3677713656111705 GSTDNLMDDIER ddPTM_PC-9_Lapatinib_30min_R1 1 GSTDNLMDDIER 12 0 P50990-2;P50990;P50990-3 P50990-2 CCT8 T-complex protein 1 subunit theta 0 118.9 0.0024998 0.0 5606.0 5679.4 5773.9 4483.6 6197.1 5488.8 6517.4 5003.9 6061.7 5373.2 False True 5526.057411985511 5666.249698241296 5299.192229898541 4813.338900851143 5832.598761967372 5254.05681901773 6854.839082116887 5236.399461635058 5378.967513469174 6301.950460661047 0.8768804906482638 0.8991263472494722 0.8408812895274138 0.7637855820825105 0.9255227882822104 0.8337191559685162 1.0877329367958637 0.8309172682842357 0.853540113818182 1.0 12.621582698103616 GSTESCNT(ph)TTEDEDLKVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSTESCNTTTEDEDLKVR 18 1 Q5SWX3;Q13555-5;Q13555-11;Q8WU40;Q13555-10;Q13555-4 Q5SWX3 CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 1 GS(0.004)T(0.016)ES(0.225)CNT(0.464)T(0.285)T(0.006)EDEDLKVR 85.177 0.0013484999999999999 9047800.0 11249.0 10500.0 11544.0 12375.0 11985.0 13400.0 10868.0 12311.0 9832.8 11102.0 True False 13153.233522122586 11542.37060791747 11819.252740863794 11681.668870291323 9636.625285042368 12697.280410648182 9838.504362493799 11987.849294582722 9976.586098169988 13114.70471661636 1.0029378324818408 0.8801090727794474 0.901221414912131 0.8907306052793261 0.7347954447523888 0.9681712768233889 0.7501887823694873 0.9140769505388933 0.7607175543593926 1.0 13.67889770460038 -1.522883999554146 0.902769242566722 0.8532623176219849 75.340308392699 0.18131817749240564 0.08639748896891562 1408.842749555741 3.0608716160193015 0.026426335396504463 216233.26655557464 0.029999637049819183 1.522883999554146 74.48704607507702 GSTESCNTT(ph)TEDEDLKVR ddPTM_PC-9_AZD4547_30min_R2 1 GSTESCNTTTEDEDLKVR 18 1 Q5SWX3;Q13555-5;Q13555-11;Q8WU40;Q13555-10;Q13555-4 Q5SWX3 CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 1 GS(0.014)T(0.055)ES(0.01)CNT(0.146)T(0.722)T(0.053)EDEDLKVR 70.501 0.044404 0.0 8476.6 7069.7 11050.0 7913.2 12716.0 11400.0 8918.0 7061.2 9069.9 8118.9 True False 11171.982475766996 9354.842269481429 10903.469780058265 6088.933997721271 10950.602894137268 10687.156197854058 9711.684723544811 5970.0537902337555 9549.31639743216 7834.659782200827 1.425969063921329 1.1940329930770228 1.391696650929159 0.7771791203434789 1.3977126255074146 1.3640868263525208 1.2395796363242606 0.7620054930524007 1.2188552742426386 1.0 12.935654912111874 -1.5228787452948322 0.12129206307412732 0.9119742013002208 2.2720803870283324 0.16128879921962513 0.21694497246193611 183.88145319964036 1.5359771940653284 1.4892763590535136 42.30224418068352 0.029999999998998744 1.5228787452948322 1.3601061857281116 GSTPY(ph)SQDSAYSSSTTSTSFKPR ddPTM_PC-9_Lapatinib_30min_R1 1 GSTPYSQDSAYSSSTTSTSFKPR 23 1 O15047 O15047 SETD1A Histone-lysine N-methyltransferase SETD1A 1 GS(0.063)T(0.196)PY(0.677)S(0.058)QDS(0.005)AYSSSTTSTSFKPR 86.439 0.00014367 6635600.0 12962.0 11578.0 15094.0 10968.0 11366.0 11662.0 8579.5 9918.5 10766.0 10765.0 True False 12777.159503060326 11551.191852350203 13853.029584524946 11774.623308175429 10697.474226415767 11163.243445449789 9023.704530184097 10379.349719264437 9553.419708994039 12625.715906539153 1.0119948522240023 0.9148940098016597 1.0972074523988091 0.9325905473666706 0.8472766459821336 0.8841671654965786 0.7147083458063958 0.8220800939999552 0.7566636046393298 1.0 13.62407757379259 -6.203383273097897 2.484068486171721 0.8205714036060067 1.0005324325433342 0.45177726947409025 0.0833306984393879 0.24756484098907774 3.0027882497390506 0.026069444115781663 0.0344477030148887 6.260611100242167e-07 6.203383273097897 0.17996102893732757 GSTPYS(ph)QDSAYSSSTTSTSFKPR ddPTM_PC-9_AZD4547_30min_R2 2 GSTPYSQDSAYSSSTTSTSFKPR 23 1 O15047 O15047 SETD1A Histone-lysine N-methyltransferase SETD1A 1 GS(0.004)T(0.017)PY(0.403)S(0.57)QDS(0.005)AYSSSTTSTSFKPR;GS(0.002)T(0.057)PY(0.382)S(0.558)QDS(0.001)AYSSSTTSTSFKPR 173.03 1.3031e-11 9857100.0 6409.900000000001 9499.900000000001 11666.2 18209.1 15290.9 15691.0 10636.599999999999 15153.5 16262.8 16509.8 True False 8448.114865797474 12570.556894330262 11511.498565440328 14011.273322790581 13168.022475146552 14709.839289519994 11583.236794175464 12811.874767788378 17122.418406835783 15931.796927192008 0.530267546366878 0.7890231686844525 0.7225486627809559 0.8794534217842356 0.8265246246436702 0.9233007021583104 0.7270514962694179 0.8041701024899067 1.0747324037009065 1.0 13.959621375335804 -3.427340299388027 0.2782030835754134 0.9509834588070513 6.172836193905233e-44 0.5593408041352304 0.09716184478681188 16.225659029098328 0.5711200278898129 0.11636257044201778 6.029760478591564 0.00037381756189321075 3.427340299388027 -0.9509834588070513 GSVFLES(ph)DSSPPSSSDAGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSVFLESDSSPPSSSDAGLR 20 0 Q8TBP0 Q8TBP0 TBC1D16 TBC1 domain family member 16 1 GSVFLES(0.489)DS(0.251)S(0.251)PPS(0.007)S(0.001)S(0.001)DAGLR 77.505 0.0019596 2759400.0 7091.9 9688.1 8408.3 4324.3 8725.1 7723.8 5855.0 9698.4 8745.6 7482.5 True False 8292.418598590204 10649.870541577644 8608.785760655319 4082.023490569759 7015.479288654419 7318.750331027195 5300.372013470852 9443.8272763042 8873.487854950312 8839.01801856259 0.9381606170703027 1.2048703282663447 0.9739527335023227 0.46181866379242675 0.7936944210229456 0.8280049113665431 0.5996562064179165 1.0684249377556947 1.0038997359565658 1.0 13.10967038522426 -5.531393927745799 24.993514382907076 0.8073864770016814 1.0759895638502632 0.23190618364827897 0.18510730651795967 239.41951507255953 702734.7753106443 0.05144378920052688 0.08928073787569295 2.9417521006959323e-06 5.531393927745799 0.2686030868485818 GSVFLESDS(ph)SPPSSSDAGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GSVFLESDSSPPSSSDAGLR 20 0 Q8TBP0 Q8TBP0 TBC1D16 TBC1 domain family member 16 1 GSVFLES(0.018)DS(0.747)S(0.233)PPS(0.001)SSDAGLR 169.06 2.7284e-08 3739800.0 7559.5 13476.0 11002.0 10142.0 10850.0 8542.2 11166.0 9895.0 7957.6 7316.3 True False 8839.174043069224 14813.808220218656 11264.329405317356 9573.77662080764 8724.0203873767 8094.231994316339 10108.275645160635 9635.266734619127 8073.964845699854 8642.687274201067 1.0227344531433737 1.7140280274213726 1.3033364563521863 1.1077314632667468 1.0094106278053607 0.9365411170757156 1.169575541085981 1.1148461617234453 0.9341961116423958 1.0 13.077264244547962 -5.750592310460223 3.3968844300230834 1.0386389422889175 1.396240646987475 0.41047796749614274 0.17032846004382615 0.20371346278171482 4.911065350761217 0.046445465558081774 0.08031321732894973 1.775855765250905e-06 5.750592310460223 0.35760170469855757 GSVFLESDSS(ph)PPSSSDAGLR ddPTM_PC-9_Lapatinib_30min_R1 1 GSVFLESDSSPPSSSDAGLR 20 0 Q8TBP0 Q8TBP0 TBC1D16 TBC1 domain family member 16 1 GSVFLES(0.003)DS(0.243)S(0.751)PPS(0.002)S(0.001)S(0.001)DAGLR 118.05 1.5338e-05 4031400.0 18268.0 40062.0 37876.0 35587.0 43937.0 37197.0 38796.0 38006.0 42136.0 30079.0 True False 18007.49497005909 39969.23890040195 34761.981485588076 38204.18669475192 41352.71204346556 35606.171020442096 40804.667049714095 39771.89750772437 37390.1999682494 35278.11507225185 0.5104437959108241 1.1329754670435872 0.9853695815208182 1.0829429695012698 1.1721916536292414 1.0092991348182399 1.1566566684796937 1.1273815912859562 1.059869550617199 1.0 15.106485858569537 -4.758518871040811 24.999994338831392 1.0848094444001317 0.5104430199703791 0.8788299327163235 0.06351243611003463 24.586828314208983 210428.8523071539 0.015240733017807116 0.10375731389491911 1.7437375866249375e-05 4.758518871040811 -0.5743664244297526 GSVGAVPSGT(ph)SPGGVATTAAAGSR ddPTM_PC-9_AZD4547_30min_R2 1 GSVGAVPSGTSPGGVATTAAAGSR 24 0 Q6ZNB6-2;Q6ZNB6 Q6ZNB6-2 NFXL1 NF-X1-type zinc finger protein NFXL1 1 GSVGAVPS(0.001)GT(0.974)S(0.025)PGGVATTAAAGSR 180.31 1.4673e-45 0.0 18544.0 16339.0 24780.0 23019.0 23831.0 14241.0 25158.0 25799.0 16023.0 16882.0 True False 24440.606260838445 21620.262223440463 24451.40100903563 17712.3251900048 20522.477003002932 13350.50801874031 27397.01326249612 21812.357352042258 16869.943068397173 16290.966318480878 1.5002551587816133 1.3271319699994653 1.5009177805062033 1.0872482849535756 1.259745837158949 0.8195037518182798 1.68173039750357 1.338923482230626 1.035539742615482 1.0 13.99178456116199 -1.5228787452803376 0.08777548614120337 0.8872161093460302 2.3452148782490903 0.1857126899249143 0.2293495356928147 338.88394072785695 2.1539230368310056 4.8334303207441005 59.54448216142338 0.029999999999999995 1.5228787452803376 1.45799876890306 GSVPLSS(ph)SPPATHFPDETEITNPVPK ddPTM_PC-9_AZD4547_30min_R2 1 GSVPLSSSPPATHFPDETEITNPVPK 26 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 GS(0.001)VPLS(0.029)S(0.362)S(0.3)PPAT(0.307)HFPDET(0.001)EITNPVPK 73.546 0.00011703 24088000.0 101720.0 119010.0 146520.0 120230.0 122440.0 146320.0 131630.0 182550.0 157050.0 155210.0 True False 134064.84409256306 157477.655132606 144577.04906553283 92512.83103498307 105441.31946824236 137170.58726929876 143344.8149989014 154341.09208168185 165351.34237607036 149776.14514224746 0.8951014459962042 1.0514201375862904 0.965287555826885 0.6176740024061943 0.7039927444260311 0.9158373460541612 0.9570603841002984 1.030478464611964 1.1039898390964102 1.0 17.19244833838369 -7.4541712230682755 2.1009248591686873 1.0511595534851865 0.8522813899176542 0.34038652370421074 0.11816498925217471 0.43862736672443253 3.801838589258437 0.07591447423805564 0.041766064555609723 3.514218631453991e-08 7.4541712230682755 -0.1988781635675323 GSVPLSS(ph)SPPATHFPDETEITNPVPK ddPTM_PC-9_Lapatinib_30min_R1 1 GSVPLSSSPPATHFPDETEITNPVPK 26 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 GS(0.002)VPLS(0.087)S(0.337)S(0.287)PPAT(0.287)HFPDETEITNPVPK 69.27 0.00017523 40210000.0 19269.0 29449.0 38502.0 32672.0 38697.0 42881.0 42264.0 39809.0 34624.0 33306.0 True False 18994.220526498175 29380.812649841166 35336.51418201798 35074.80787059697 36420.91854122919 41047.07959049326 44452.223120659764 41658.67146989948 30724.280513116268 39062.89772254463 0.48624709465769905 0.7521411457625793 0.9046055526398898 0.8979059392809462 0.9323660215870095 1.050794538644876 1.1379653254705873 1.06645113134699 0.7865335728891449 1.0 15.253511353220732 -4.513564159714661 0.82987922536856 1.0066458999357897 1.43398128476784e-17 0.7512958114275387 0.08977357514464711 1.8177657112214738 0.7146011667922121 0.034413883936855454 1.8629562943067788 3.065037838121005e-05 4.513564159714661 -1.0066458999357897 down GSVPLSSSPPAT(ph)HFPDETEITNPVPK ddPTM_PC-9_AZD4547_30min_R2 2 GSVPLSSSPPATHFPDETEITNPVPK 26 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 GSVPLS(0.007)S(0.079)S(0.064)PPAT(0.85)HFPDETEITNPVPK;GSVPLS(0.051)S(0.177)S(0.145)PPAT(0.627)HFPDETEITNPVPK 89.62200000000001 1.3609e-06 538030000.0 282700.0 340830.0 417970.0 360560.0 334820.0 403610.0 380960.0 519380.0 411220.0 385490.0 True False 372592.7194747104 450996.6322060844 412427.4447032533 277438.46259646903 288336.0224138907 378372.2028961295 414864.7019826908 439121.75516507286 432956.2496777313 371994.1124340235 1.0016091841797443 1.212375726204733 1.1086934736807184 0.7458141226514041 0.7751091019351272 1.017145675829042 1.1152453442560082 1.1804535085026515 1.1638793067041349 1.0 18.504920262357608 -7.208224222819392 4.147576984204017 1.1311643966795493 0.9714980291886147 0.19594884443512828 0.13741337032996528 0.39841505174453223 14.431200533670852 0.06345501648297455 0.047041052580595606 6.191213450741654e-08 7.208224222819392 -0.15966636749093455 GSVPLSSSPPAT(ph)HFPDETEITNPVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GSVPLSSSPPATHFPDETEITNPVPK 26 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 GS(0.002)VPLS(0.023)S(0.07)S(0.07)PPAT(0.834)HFPDET(0.002)EITNPVPK;GS(0.002)VPLS(0.023)S(0.184)S(0.184)PPAT(0.596)HFPDET(0.011)EIT(0.001)NPVPK;GSVPLS(0.002)S(0.031)S(0.122)PPAT(0.845)HFPDETEITNPVPK;GSVPLS(0.005)S(0.08)S(0.063)PPAT(0.852)HFPDETEITNPVPK;GSVPLS(0.005)S(0.069)S(0.056)PPAT(0.87)HFPDETEITNPVPK 135.31 8.5896e-12 417531000.0 365163.0 517931.0 488987.0 402165.0 449512.0 330254.0 414675.0 317678.0 314994.0 285664.0 True False 426977.88360199565 569347.7667932666 500646.3045735232 379632.9988865215 361433.35044889164 312934.8988610597 375393.9820129846 309339.2891076634 319600.19133989885 337452.6218850209 1.265297277042578 1.6871931935596534 1.4836047258335028 1.1249964417697502 1.071063986493611 0.9273446954212284 1.1124346283517432 0.9166895411263496 0.9470964829213718 1.0 18.36432543743109 -5.858432397230012 2.8504552646597316 0.9976761006618704 1.5077105367841155 0.7888605529356323 0.1115154987145581 0.10737601771318545 1.7591679775346176 0.03220875355664041 0.05301313120456796 1.3853758183071694e-06 5.858432397230012 0.5100344361222451 GSVPLSSSPPAT(ph)HFPDETEITNPVPK ddPTM_PC-9_Lapatinib_30min_R1 3 GSVPLSSSPPATHFPDETEITNPVPK 26 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 GS(0.003)VPLS(0.011)S(0.042)S(0.163)PPAT(0.763)HFPDET(0.016)EITNPVPK;GS(0.001)VPLS(0.019)S(0.063)S(0.207)PPAT(0.709)HFPDET(0.001)EITNPVPK;GS(0.001)VPLS(0.039)S(0.146)S(0.12)PPAT(0.694)HFPDETEITNPVPK 90.084 1.2136e-06 472922000.0 168144.0 311937.0 336651.0 302572.0 298696.0 331106.0 360570.0 348472.0 332375.0 286323.0 True False 165746.235726167 311214.729041852 308972.8542904407 324824.15423060267 281127.28853893076 316945.36822578416 379238.55031744007 364663.2812795801 294939.4274360849 335813.54904858366 0.49356625483323713 0.9267485779640986 0.9200726271045728 0.9672753084289905 0.8371529062344617 0.943813521294015 1.1293128326474222 1.085909970913123 0.8782832862810269 1.0 18.357300914214022 -4.73930132038603 3.4843553955837807 0.9714144873183509 0.4081664203067591 0.7447832186949752 0.08316525367254697 0.1974962353308496 3.615479441921957 0.022981491914577754 0.31281077537504465 1.82263069350308e-05 4.73930132038603 -0.5632480670115918 down GSVS(ph)DEEMMELR ddPTM_PC-9_AZD4547_30min_R2 5 GSVSDEEMMELR 12 0 P13796;Q5TBN3;Q5TBN5 P13796 LCP1 Plastin-2 1 GS(0.034)VS(0.966)DEEMMELR;GS(0.251)VS(0.749)DEEMMELR;GS(0.301)VS(0.699)DEEMMELR;GS(0.25)VS(0.75)DEEMMELR;GS(0.087)VS(0.913)DEEMMELR 127.52 0.00020409 370025200.0 572365.0 648456.0 799580.0 845529.0 747581.0 806265.0 748327.0 954715.0 792403.0 735264.0 True False 754365.1640684207 858056.7207517786 788977.0467637092 650605.3523428288 643792.282337372 755849.1220932291 814926.6532985114 807185.7339181744 834287.804857214 709522.6311569432 1.0632009902747677 1.2093436954260877 1.1119829193851198 0.9169620865820104 0.9073597572040912 1.0652924782127755 1.1485562510806697 1.1376462123582758 1.1758438254419448 1.0 19.436489176111195 -9.597303965831019 12.986305677661868 0.9999999997670115 1.07957964847489 0.061096275262156885 0.09584441310065148 0.0 0.0 0.10465983927714018 0.025383739535283348 2.5275283419587254e-10 9.597303965831019 0.07957964870787859 GSVS(ph)DEEMMELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSVSDEEMMELR 12 0 P13796;Q5TBN3;Q5TBN5 P13796 LCP1 Plastin-2 1 GS(0.408)VS(0.592)DEEMMELR;GS(0.35)VS(0.65)DEEMMELR 89.029 0.0067928 84063000.0 75430.0 89157.0 125234.0 117580.0 169332.0 168391.0 208429.0 175941.0 172439.0 136582.0 True False 88198.80918959058 98007.91774191434 128220.05351258974 110992.37379950349 136152.6101599329 159560.27952458634 188685.09622471652 171322.73517489905 174960.59415246226 161343.23541748294 0.5466532821247334 0.6074498102651432 0.7947036216350474 0.6879270364964833 0.8438693435620765 0.9889492987525438 1.1694639427335474 1.0618526071551355 1.084399935948624 1.0 17.299773566149277 -6.476272508567715 1.111036357233453 1.0930147132899777 0.6242130626266428 0.8841088415216689 0.06941423379033217 0.15719243666323948 0.4102152289731265 0.033722124177487295 0.040498330321816586 3.339854070486986e-07 6.476272508567715 -0.4688016506633349 GSVS(ph)DEEMMELR ddPTM_PC-9_Lapatinib_30min_R1 2 GSVSDEEMMELR 12 0 P13796;Q5TBN3;Q5TBN5 P13796 LCP1 Plastin-2 1 GS(0.048)VS(0.952)DEEMMELR;GS(0.348)VS(0.652)DEEMMELR 128.57 0.00017702 52623000.0 41095.0 61398.0 73122.0 59899.0 113953.0 155581.0 185313.0 171220.0 169443.0 136654.0 True False 40508.97776409998 61255.836703281886 67110.19141908271 64304.172277206424 107250.508580218 148927.16330702484 194907.60039652724 179175.5062693412 150358.54502610784 160274.46181999042 0.25274755131979143 0.3821933700958569 0.41872042905036483 0.40121284169045335 0.669167797304318 0.929200832221729 1.2160864443608892 1.117929233607904 0.9381316481660099 1.0 17.290185038788607 -6.594645189197788 1.7437367356892524 1.080475456704525 0.3564282052902285 0.9390740426606322 0.08186635903102321 0.08056248481523008 0.5010742029098009 0.03352422462398943 0.03469121802430512 2.5430494829042806e-07 6.594645189197788 -0.7240472514142964 down GSVS(ph)SVSPKPPSSFK ddPTM_PC-9_Lapatinib_30min_R1 1 GSVSSVSPKPPSSFK 15 1 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 GS(0.003)VS(0.46)S(0.426)VS(0.112)PKPPSSFK 69.52199999999999 0.012071 30887000.0 98244.0 78012.0 76820.0 82883.0 71713.0 53426.0 47203.0 54181.0 43743.0 40685.0 True False 96843.0225442567 77831.3680070429 70504.15613377548 88978.49230958284 67494.98233318269 51141.09452208886 49646.94037394719 56698.44705746497 38816.202705789154 47717.34804064518 2.0295139298555895 1.6310916512113558 1.4775371857153654 1.8646990237972114 1.414474716316823 1.0717505607924265 1.04043796255522 1.1882145463987182 0.8134610220317752 1.0 15.542226244985677 -6.594423839310111 2.6471373203441777 1.0284847620104018 1.7231436279900079 0.817764783891932 0.1617565822992285 0.1196776750425565 1.7022444905061094 0.05768352378305374 0.05898720667849646 2.544345946973613e-07 6.594423839310111 0.694658865979606 GSVSQPS(ph)TPSPPKPTGIFQTSANSSFEPVK ddPTM_PC-9_AZD4547_30min_R2 2 GSVSQPSTPSPPKPTGIFQTSANSSFEPVK 30 1 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0 O15027 SEC16A Protein transport protein Sec16A 1 GS(0.001)VS(0.009)QPS(0.35)T(0.128)PS(0.128)PPKPT(0.311)GIFQT(0.029)S(0.029)ANS(0.011)S(0.004)FEPVK;GS(0.002)VS(0.02)QPS(0.54)T(0.052)PS(0.15)PPKPT(0.131)GIFQT(0.041)S(0.041)ANS(0.016)S(0.005)FEPVK 59.888000000000005 0.00051512 29294000.0 39336.0 43693.0 52475.0 72030.0 71523.0 56637.0 47346.0 58996.0 53245.0 48826.0 True False 51844.02976037213 57815.9077868159 51779.14721344412 55424.59635240648 61593.266026846424 53095.479436654394 51559.702278644625 49879.52379321233 56059.4219981781 47116.61660147777 1.1003343087828188 1.2270810588085086 1.0989572458354344 1.1763280207744826 1.307251463911664 1.1268949951510123 1.094299760841221 1.0586397621693384 1.1898015189065982 1.0 15.52394832390622 -9.045208626142752 0.42426222225762306 0.9891622965056833 1.1761446902279968 0.3041129911445819 0.07031655941639703 2.925597552973765 0.9789506834253644 0.15811782676558042 0.0489449616641249 9.011381453706758e-10 9.045208626142752 0.1869823937223135 GSVSQPSTPS(ph)PPKPTGIFQTSANSSFEPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSVSQPSTPSPPKPTGIFQTSANSSFEPVK 30 1 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0 O15027 SEC16A Protein transport protein Sec16A 1 GSVSQPS(0.016)T(0.037)PS(0.945)PPKPT(0.002)GIFQTSANSSFEPVK;GSVSQPS(0.002)T(0.049)PS(0.605)PPKPT(0.305)GIFQT(0.016)S(0.016)ANS(0.007)S(0.002)FEPVK 123.35 6.2985e-18 19130500.0 43551.0 48216.0 41005.0 64899.0 70480.0 73389.0 68378.0 69185.0 60280.0 59967.0 True False 50923.32412854126 53002.56583155701 41982.71471232848 61262.91943539685 56669.94994491336 69540.3516460492 61900.74082615025 67368.96705756689 61161.48096144408 70838.5424014891 0.7188646519563451 0.7482164939413384 0.5926535652637308 0.8648246753607544 0.7999875212525843 0.9816739487935509 0.8738285504989305 0.9510213617290736 0.8633927080938696 1.0 16.112246906549245 -6.1713986301288015 1.6310519118682605 0.9229434756251659 0.6968010207909937 0.6659631786832385 0.06987841613169765 0.21858919143563318 1.1556207582648934 0.023310910317371012 0.03385207917264222 6.739091761111594e-07 6.1713986301288015 -0.22614245483417217 GSVSQPSTPS(ph)PPKPTGIFQTSANSSFEPVK ddPTM_PC-9_Lapatinib_30min_R1 2 GSVSQPSTPSPPKPTGIFQTSANSSFEPVK 30 1 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0 O15027 SEC16A Protein transport protein Sec16A 1 GSVSQPST(0.001)PS(0.803)PPKPT(0.19)GIFQT(0.004)S(0.001)ANSSFEPVK;GSVSQPS(0.002)T(0.009)PS(0.97)PPKPT(0.018)GIFQT(0.001)SANSSFEPVK 117.03 2.7913e-17 22857000.0 109229.0 90914.0 90766.0 88480.0 113591.0 110966.0 101306.0 110565.0 110013.0 95768.0 True False 107671.3744298546 90703.49421873948 83303.56984689218 94987.11436062721 106909.8007084985 106220.24285438021 106551.12898593493 115702.25353737679 97622.1774517519 112321.37119716151 0.9586009615289985 0.8075354961570453 0.7416537828822138 0.8456726742935955 0.9518206514843565 0.9456815005216435 0.9486273880943114 1.0301000807253387 0.8691327074381274 1.0 16.777272927436137 -6.242183876108361 4.414963266132376 0.9588020431768458 0.8275269466060929 0.4581052184501839 0.06334514431008674 0.1805998889814587 8.955453802294333 0.019459107762608317 0.024328690506001317 5.725535659854282e-07 6.242183876108361 -0.13127509657075287 GSVSS(ph)VSPKPPSSFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSVSSVSPKPPSSFK 15 1 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 GS(0.001)VS(0.185)S(0.797)VS(0.017)PKPPSSFK;GS(0.01)VS(0.183)S(0.772)VS(0.035)PKPPSSFK 77.372 0.0061288 52258000.0 252520.0 267736.0 264750.0 331550.0 303810.0 228857.0 272330.0 234251.0 228067.0 200283.0 True False 295266.648502658 294315.06067441846 271062.6440699659 312974.32839960314 244280.61141833375 216855.33604027668 246532.9309015405 228102.15945945014 231402.04841462555 236592.722460644 1.2479954811449203 1.2439734308538433 1.1456930764852915 1.3228400482676081 1.0324941903442046 0.9165765277347002 1.0420140076056228 0.9641131691926567 0.9780607197379797 1.0 17.85204617181944 -6.393365844972243 5.244557210416005 0.9812147760789893 1.2325627828166426 0.8592775793493632 0.050069070873494194 0.0778717445810562 2.9995524868793972 0.015011911832951572 0.017022239743916413 4.0423522485119533e-07 6.393365844972243 0.25134800673765323 GSVSS(ph)VSPKPPSSFK ddPTM_PC-9_Lapatinib_30min_R1 1 GSVSSVSPKPPSSFK 15 1 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 GS(0.001)VS(0.146)S(0.734)VS(0.119)PKPPSSFK 68.845 0.012722 32948000.0 206960.0 163990.0 154600.0 165980.0 134640.0 129610.0 104290.0 109380.0 110730.0 102490.0 True False 204008.71244818383 163610.29123051531 141889.38477325792 178186.7228930489 126720.73991242485 124066.88243566683 109689.6259051108 114462.19411132189 98258.42136140709 120205.25994065907 1.6971695959802044 1.361090948193812 1.1803924790254894 1.4823537920138699 1.0542029523082619 1.032125237255958 0.912519351975617 0.9522228408958783 0.8174219781223689 1.0 16.87514050130349 -5.247264846079656 0.4275028244521557 0.8711882019897565 1.9324110007446986 0.7876059411014105 0.12254242842533626 1.6772426558054703 0.32231188382261033 0.10181952833439753 0.8721023204771401 5.6589408424201214e-06 5.247264846079656 1.061222798754942 GSVSSVS(ph)PKPPSSFK ddPTM_PC-9_AZD4547_30min_R2 2 GSVSSVSPKPPSSFK 15 1 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 GS(0.001)VS(0.315)S(0.241)VS(0.442)PKPPSSFK;GS(0.001)VS(0.061)S(0.282)VS(0.654)PKPPS(0.001)S(0.001)FK 78.501 0.0055826999999999995 56130000.0 255260.0 240720.0 290160.0 284610.0 295180.0 305740.0 320790.0 299900.0 274370.0 307650.0 True False 336427.37026216614 318528.03246383404 286312.2888128238 218997.56168066667 254199.35217768484 286622.0294677102 349339.688547426 253557.34601641365 288872.6380625435 296879.2671413722 1.133212748406447 1.0729211087420019 0.9644064793399115 0.7376653943853253 0.8562381422769969 0.9654498012864685 1.1767062480017254 0.8540756262904378 0.9730306896944206 1.0 18.1795168192375 -5.213227786333535 3.4159891176781176 0.933773829455796 1.1168134715344165 0.26974321257924616 0.10848613176704358 0.3380375681146428 7.977914450815027 0.03084614137945958 0.09340030087274158 6.120292997399553e-06 5.213227786333535 0.18303964207862045 GSVSSVS(ph)PKPPSSFK ddPTM_PC-9_Lapatinib_30min_R1 1 GSVSSVSPKPPSSFK 15 1 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 GSVS(0.017)S(0.056)VS(0.644)PKPPS(0.142)S(0.142)FK 98.421 0.010904 5139600.0 26736.0 22087.0 22900.0 23161.0 20993.0 15789.0 14876.0 14989.0 17350.0 16743.0 True False 26354.739737218075 22035.858908521233 21017.250396556323 24864.337202831062 19758.23301382599 15113.74127595667 15646.206491172985 15685.443660034747 15395.860296400391 19637.00524135486 1.3420956715800991 1.1221598526701246 1.070287965921337 1.2661980224187965 1.0061734348481932 0.7696561206862466 0.7967715188170654 0.7987696426847074 0.7840228236012913 1.0 14.261287306509496 -6.536801371889675 3.6932579025901613 0.8166139792307718 1.1837496342738738 0.7751082069579547 0.09354430445121505 0.10343098243132097 3.0786533353093493 0.03079684479033325 0.03232669560989305 2.905351136596112e-07 6.536801371889675 0.36713565504310197 GSWDCSSPEGNGS(ph)PEPK ddPTM_PC-9_AZD4547_30min_R2 1 GSWDCSSPEGNGSPEPK 17 0 Q9UN79;E9PPW0 Q9UN79 SOX13 Transcription factor SOX-13 1 GSWDCSSPEGNGS(1)PEPK 287.31 1.1920999999999994e-221 0.0 17008.0 16445.0 17576.0 23837.0 19939.0 18315.0 19033.0 21108.0 16108.0 18876.0 True False 22416.19021162319 21760.524650497497 17342.930756045607 18341.747927978802 17170.81402219275 17169.760154710264 20726.900128193367 17846.24361358609 16959.435994866235 18215.15698540725 1.2306339291822477 1.194638326089122 0.9521153602979973 1.0069497585265375 0.9426662661183124 0.9426084094946594 1.1378930274824617 0.9797469013241715 0.9310617530473652 1.0 14.152851808398609 -5.219237000272035 6.254531609528517 0.9888810473159316 1.2163468797713866 0.71690530106015 0.05681988090834955 0.11274173908478863 12.01279051565904 0.015027523819494543 0.03995631278974322 6.036191364932839e-06 5.219237000272035 0.22746583245545493 GSWDCSSPEGNGS(ph)PEPK ddPTM_PC-9_Lapatinib_30min_R1 3 GSWDCSSPEGNGSPEPK 17 0 Q9UN79;E9PPW0 Q9UN79 SOX13 Transcription factor SOX-13 1 GSWDCSS(0.08)PEGNGS(0.919)PEPK;GSWDCSSPEGNGS(1)PEPK;GSWDCSSPEGNGS(1)PEPK 297.55 1.4746999999999993e-248 9278000.0 60063.0 61233.0 60774.0 59524.0 72579.0 55413.0 55312.0 57122.0 63225.0 52435.0 True False 59206.49060579476 61091.21875064428 55777.39631442418 63901.59352624305 68310.04591580416 53043.11516401209 58175.784716305476 59776.096654113346 56103.9347112343 61498.31988475427 0.9627334651864584 0.9933802885205175 0.9069743111510866 1.0390786877754128 1.1107627987856388 0.8625132404171862 0.9459735619659998 0.9719956051829007 0.9122840236346479 1.0 15.908259376553476 -6.785788718829689 24.99999715893233 0.9372668366756025 0.9987902386496345 0.22341895886118224 0.059456005546801693 400.5195496979996 411219.041595234 0.02170453775830645 0.019150857642956834 1.6376130147286473e-07 6.785788718829689 0.061523401974031944 GSYGDLGGPIITTQVTIPK ddPTM_PC-9_Lapatinib_30min_R1 2 GSYGDLGGPIITTQVTIPK 19 0 P61978;P61978-2;P61978-3;Q5T6W2;S4R359 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 ; 246.96 4.0605999999999995e-53 21063100.0 189782.0 215102.0 205719.0 214067.0 206114.0 202620.0 212420.0 193524.0 193182.0 190261.0 False True 187075.6738782439 214603.94453482726 188805.57791830416 229810.2012865785 193990.77975571508 193954.41493028938 223418.06822095747 202515.8315340955 171423.80886335557 223147.36034315306 0.8383503779321494 0.9617140180587938 0.846102672368436 1.0298584797650279 0.8693393435503723 0.8691763802718923 1.0012131350215756 0.9075430299631119 0.7682089924780751 1.0 17.767637215185815 -4.735886656308922 23.969860006657814 0.9150844049768979 0.8383497770539466 0.08375190261731136 0.07782295597247026 4030.035262507938 3780060.7728232965 0.01856957874438932 1.250899891282633 1.837017712092014e-05 4.735886656308922 -0.07673462792295127 GSYGS(ph)DAEEEEYR ddPTM_PC-9_AZD4547_30min_R2 1 GSYGSDAEEEEYR 13 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-6;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 GSYGS(1)DAEEEEYR 161.21 0.00030289 155100000.0 14495.0 11618.0 9721.8 12461.0 15150.0 11054.0 12885.0 9078.9 7937.5 11035.0 True False 19104.10848527034 15373.29129762724 9592.882579888728 9588.308970530858 13046.684008035507 10362.791632550769 14031.74003844752 7675.964617367194 8357.060045272581 10648.668008792585 1.7940373828441372 1.4436820910308727 0.9008528176451649 0.9004233170396343 1.225193986446275 0.9731537901260732 1.31769908000339 0.7208380063148897 0.7847986281826208 1.0 13.378385361428741 -5.033435548287478 2.913405391768992 0.986299356727237 1.7829822285844505 0.7028595365459596 0.17334022251844733 0.15796778533899328 2.5046216699546355 0.0475731433332 0.22330392214076333 9.259007837425579e-06 5.033435548287478 0.7966828718572135 GSYGS(ph)DAEEEEYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GSYGSDAEEEEYR 13 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-6;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 GS(0.01)YGS(0.988)DAEEEEY(0.002)R;GS(0.002)YGS(0.998)DAEEEEYR 127.79 0.00011279 4715100.0 20297.4 26536.0 23827.0 23949.0 25364.0 16236.6 23892.0 17440.2 19794.7 17389.1 True False 23733.348928076368 29170.318709685514 24395.1260444007 22607.21517370559 20394.10627699749 15385.124113099273 21628.776796899325 16982.41322941934 20084.160039606788 20541.606177960137 1.155379414952506 1.4200602648581322 1.187595840026139 1.1005573263283435 0.9928194562934953 0.7489737647490561 1.0529252975410295 0.8267324902587418 0.9777307512182684 1.0 14.32626137203233 -5.973532042871682 1.7409517768126341 0.9177398250102241 1.286009299323606 0.6642870117914516 0.10378765923932813 0.19381129599365587 1.187018312222966 0.032615577514036154 0.055294259604344004 1.0628401625064586e-06 5.973532042871682 0.368269474313382 GSYGS(ph)DAEEEEYR ddPTM_PC-9_Lapatinib_30min_R1 2 GSYGSDAEEEEYR 13 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-6;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 GS(0.093)YGS(0.907)DAEEEEYR;GS(0.003)Y(0.001)GS(0.996)DAEEEEYR 91.712 0.0049783 290750000.0 23147.2 33994.0 33486.0 28372.8 32180.0 32991.0 29673.0 36273.0 33636.4 25672.8 True False 22817.11668332341 33915.288981585116 30732.91033969805 30459.430360886203 30287.235668314206 31580.051835777227 31209.32274889593 37958.37600109682 29847.91442500532 30110.309273144285 0.7577842019601654 1.1263680048558828 1.0206773388112977 1.0115947360279458 1.0058759408136575 1.0488119384394308 1.0364995744740446 1.2606438431687685 0.9912855478913 1.0 14.877969906095602 -4.753533034478933 24.973115223592522 1.0590429445722749 0.7577836488273124 0.5691483865475119 0.07772747780648379 211.2667137592267 667256.5215429099 0.019366689094585263 0.20603182511469212 1.7638715910123514e-05 4.753533034478933 -0.30125929574496246 GSYGS(ph)DAEEEEYRQQLSEHSK ddPTM_PC-9_AZD4547_30min_R2 6 GSYGSDAEEEEYRQQLSEHSK 21 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-6;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 GS(0.263)Y(0.007)GS(0.73)DAEEEEYRQQLSEHSK;GS(0.07)Y(0.022)GS(0.906)DAEEEEY(0.001)RQQLS(0.001)EHSK;GS(0.282)Y(0.001)GS(0.717)DAEEEEYRQQLSEHSK;GS(0.01)Y(0.005)GS(0.985)DAEEEEYRQQLSEHSK;GS(0.219)Y(0.012)GS(0.767)DAEEEEY(0.001)RQQLS(0.001)EHSK;GS(0.236)Y(0.013)GS(0.751)DAEEEEYRQQLSEHSK 65.21300000000001 0.0020664000000000004 486756000.0 114788.7 80132.9 242799.0 409791.0 304987.0 262659.0 169431.0 313334.0 199628.9 271605.0 True False 151289.11884671648 106034.29284073283 239579.32661795183 315320.01615783694 262644.8195088268 246234.89120808314 184510.03076866094 264915.4299990228 210180.87610352333 262096.19162012762 0.5772274595503823 0.4045625088456644 0.9140893087267331 1.2030698126848403 1.0020932310588258 0.9394829039140208 0.7039782975407856 1.0107565026468652 0.8019226636003609 1.0 17.99973686522381 -5.291093113671422 8.378511335034865 0.9499319230565175 0.49092833095904287 0.659673097597496 0.13101606150538306 0.15840617033602913 42.03871662154927 0.0358334169881825 0.07649135847767778 5.115721416134737e-06 5.291093113671422 -0.45900359209747466 GSYGS(ph)DAEEEEYRQQLSEHSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GSYGSDAEEEEYRQQLSEHSK 21 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-6;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 GS(0.006)Y(0.003)GS(0.991)DAEEEEYRQQLSEHSK;GS(0.062)Y(0.002)GS(0.936)DAEEEEYRQQLSEHSK;GS(0.26)Y(0.025)GS(0.715)DAEEEEYRQQLSEHSK;GS(0.033)Y(0.115)GS(0.846)DAEEEEY(0.004)RQQLS(0.001)EHSK;GS(0.158)Y(0.067)GS(0.774)DAEEEEY(0.001)RQQLSEHSK 89.62200000000001 0.00020173 197067200.0 72828.8 79201.29999999999 132371.5 187971.0 221498.0 189474.6 155229.1 160930.1 166329.0 118064.20000000001 True False 85157.27740563246 87063.88164084329 135527.73858170924 177439.5942802042 178097.05693669754 179538.2184250297 140524.6758866387 156705.8553945357 168761.2469614467 139468.30486430737 0.6105851611840006 0.6242556810706933 0.9717457935232524 1.272257481388622 1.2769715464024114 1.2873048008987238 1.0075742730461885 1.123594751847018 1.2100329686063027 1.0 17.08957777132631 -5.399371086929151 2.9239951048868758 1.1752143399720263 0.6072307600341154 0.827850287073182 0.09920444830173472 0.10215630824826488 1.6512436894998848 0.02861181834581527 0.07070823937971445 3.986840974734894e-06 5.399371086929151 -0.5679835799379109 GSYGS(ph)DAEEEEYRQQLSEHSK ddPTM_PC-9_Lapatinib_30min_R1 5 GSYGSDAEEEEYRQQLSEHSK 21 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-6;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 GS(0.025)Y(0.015)GS(0.959)DAEEEEYRQQLS(0.001)EHSK;GS(0.322)Y(0.011)GS(0.667)DAEEEEYRQQLSEHSK;GS(0.279)Y(0.001)GS(0.719)DAEEEEYRQQLSEHSK;GS(0.014)Y(0.008)GS(0.967)DAEEEEY(0.005)RQQLS(0.006)EHSK;GS(0.077)Y(0.002)GS(0.921)DAEEEEYRQQLSEHSK 82.21600000000001 0.00031489 411633000.0 238472.0 170527.0 356628.0 215215.0 256484.0 293364.0 182469.0 223934.0 384964.0 211265.0 True False 235071.34554959062 170132.15520864786 327307.4224638902 231042.62903619363 241398.11538694546 280817.505584885 191916.3519923262 234338.79115125953 341605.30046936456 247781.87375708277 0.9487027520828536 0.6866206661082879 1.3209498237339656 0.9324436268598899 0.9742363786610326 1.1333254581010608 0.7745374957511004 0.945746303383748 1.378653310226652 1.0 17.918711126817442 -5.233329525948906 24.988687634471415 1.0407131504856264 0.8176617412962552 0.21218375465879913 0.18257162441457966 1177.2285152716938 1046511.8515217969 0.04537204631776066 0.11998604570036368 5.843465362158342e-06 5.233329525948906 -0.22305140918937116 GSYLTHEAS(ph)GLDEQGEAR ddPTM_PC-9_Lapatinib_30min_R1 1 GSYLTHEASGLDEQGEAR 18 0 Q8NFZ8 Q8NFZ8 CADM4 Cell adhesion molecule 4 1 GSYLTHEAS(1)GLDEQGEAR 92.913 0.00061721 1501700.0 20916.0 31270.0 13882.0 7488.7 13617.0 9530.3 8806.0 8248.3 18154.0 5262.9 True False 20617.734004475366 31197.59623622308 12740.67554606964 8039.44397957087 12816.074832052047 9122.711285214384 9261.931591911085 8631.546129899567 16109.305349905057 6172.585252626555 3.3402104889036757 5.0542187688615385 2.0640744557798105 1.302443571135762 2.0762896432412266 1.4779401031897441 1.5004947218784792 1.3983680705303625 2.6098149625475378 1.0 12.591659141942204 -5.371732579983972 5.406368784939986 1.6531601659085944 4.1775287803290935 0.7576463766037629 0.5729291942747987 0.08987748010665902 3.6761019308941796 0.14003444138296597 0.2995716231370903 4.248811070758587e-06 5.371732579983972 2.5243686144204993 GT(ph)ES(ph)MDT(ph)T(ph)Y(ph)SPIGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTESMDTTYSPIGGK 15 0 Q9UKZ4;Q9UKZ4-2 Q9UKZ4 TENM1 Teneurin-1;Ten-1 intracellular domain;Teneurin C-terminal-associated peptide 5 GT(0.993)ES(0.994)MDT(0.891)T(0.891)Y(0.867)S(0.365)PIGGK 42.336000000000006 0.044953 0.0 2850.7 3701.2 3398.4 3647.0 5115.2 4480.3 3859.0 5019.0 5182.7 2878.7 True False 3333.2672061085286 4068.630675621347 3479.4307445037703 3442.670413733532 4112.91327977044 4245.345180882614 3493.447583259441 4887.256568070075 5258.48718279489 3400.5855222233395 0.9802039043938535 1.1964500375103733 1.0231857783799776 1.012375778005041 1.2094720902891372 1.2484159428247408 1.027307668173388 1.4371809019744148 1.5463475770363317 1.0 11.731567459636768 -7.103852988361116 1.022522531755253 1.325370742564083 1.070643962520513 0.22214165764297011 0.16572382987391132 0.7430271962775943 1.5664297754644092 0.11120478021563367 0.07257265060355324 7.873122551509089e-08 7.103852988361116 -0.25472678004356997 GT(ph)LQGAALRS(ph)RERPS(ph)WPQET(ph)HGHR ddPTM_PC-9_AZD4547_30min_R2 1 GTLQGAALRSRERPSWPQETHGHR 24 3 Q9NZY2 Q9NZY2 KIAA0125 Putative uncharacterized protein KIAA0125 4 GT(1)LQGAALRS(1)RERPS(1)WPQET(1)HGHR 65.301 0.0040646 0.0 2159.1 1218.5 616.12 3958.9 1943.2 2241.0 2590.1 2440.5 2755.2 2336.6 True False 2845.6488879301282 1612.356295933792 607.9498462343436 3046.23676939528 1673.4202220735713 2100.869915736048 2820.6138823114406 2063.376802110899 2900.8342471477195 2254.7963452056883 1.262042531681743 0.7150784590200799 0.2696251692650694 1.3510030632577572 0.7421602512491733 0.9317337772890532 1.2509395308843898 0.9151056176307011 1.2865171851620585 1.0 11.138781418794606 -7.043939549849617 7.788632692862553 1.1047419487528654 0.8513818201708937 0.13080395426759972 0.298090774023506 0.607408298301171 96.85919704094105 0.11296474763295683 0.08844932603954454 9.037752629062663e-08 7.043939549849617 -0.25336012858197166 GT(ph)PDTDLEVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTPDTDLEVQR 11 0 P0C7T5 P0C7T5 ATXN1L Ataxin-1-like 1 GT(0.911)PDT(0.089)DLEVQR 97.95700000000001 0.012654 5238200.0 8730.2 13611.0 12489.0 10145.0 12358.0 10307.0 9147.9 9176.0 8009.4 9044.5 True False 10208.050430690248 14962.210128034729 12786.78512479625 9576.608540533769 9936.538612645272 9766.482775563496 8281.344686939372 8935.139722775646 8126.522322703877 10684.1962537774 0.9554345678629022 1.4004057743459024 1.1967942951511659 0.8963340164355327 0.9300220977438717 0.9141055203015906 0.7751022622793456 0.8362949828459605 0.7606114797667389 1.0 13.383190761173392 -5.776944569500755 4.92688940451854 0.8639216876844724 1.2091693549081695 0.5805363179642183 0.12073781777648415 0.1151508124335485 7.324267879069407 0.03313382016159192 0.05334233545991304 1.671303914968325e-06 5.776944569500755 0.34524766722369704 GT(ph)PDTDLEVQR ddPTM_PC-9_Lapatinib_30min_R1 1 GTPDTDLEVQR 11 0 P0C7T5 P0C7T5 ATXN1L Ataxin-1-like 1 GT(0.99)PDT(0.01)DLEVQR 112.84 0.0040027000000000005 6317500.0 10261.0 11520.0 9656.6 11713.0 12227.0 10488.0 10807.0 7777.5 11751.0 8199.2 True False 10114.676258363053 11493.326147786684 8862.671623553968 12574.413093422569 11507.831899206902 10039.452688722124 11366.533580942889 8138.871043159664 10427.478636484208 9616.420795252745 1.051812984656025 1.1951771238484588 0.9216185327423615 1.3075980514111936 1.1966855594430594 1.043990576377254 1.1819921177486437 0.8463513833730643 1.0843409266815622 1.0 13.23128431152877 -7.743145420175444 24.999512849241043 0.9740095422631049 1.1292959579061224 0.27190788050167136 0.11358077752709536 294.46736114011986 402403.97839989286 0.05182196577116451 0.029846520308483372 1.8065691089174337e-08 7.743145420175444 0.15528641564301748 GT(ph)PPLTPSDSPQTR ddPTM_PC-9_AZD4547_30min_R2 1 GTPPLTPSDSPQTR 14 0 Q6NZY4-2;Q6NZY4 Q6NZY4-2 ZCCHC8 Zinc finger CCHC domain-containing protein 8 1 GT(1)PPLTPSDSPQTR 108.66 0.0016237000000000003 5823900.0 4553.4 2843.9 6501.7 7136.1 7500.9 5071.2 4225.1 1947.5 4970.6 7814.5 True False 6001.286483396341 3763.1350595043996 6415.483209864688 5490.982396645957 6459.529509958653 4754.097062329607 4601.12571489675 1646.5586240979205 5233.335768318979 7540.916733548684 0.7958298301713501 0.4990288571630341 0.850756404897422 0.7281584707356864 0.8565973790986099 0.6304402011467874 0.6101546904008186 0.21834992777105838 0.6939919844276309 1.0 12.880524204250243 -6.970179813446334 8.690309859464147 0.5731330046026709 0.7380119885900068 0.04589810737478328 0.2028292655461282 0.5336670172873662 140.3363986947084 0.06969162881631714 0.06109236497814327 1.0710757497568357e-07 6.970179813446334 0.16487898398733591 GT(ph)PPPVFTPPLPK ddPTM_PC-9_AZD4547_30min_R2 1 GTPPPVFTPPLPK 13 0 Q6NZY4-2;Q6NZY4 Q6NZY4-2 ZCCHC8 Zinc finger CCHC domain-containing protein 8 1 GT(1)PPPVFTPPLPK 158.58 0.00061099 10795000.0 47106.0 54273.0 63381.0 78067.0 75050.0 76406.0 51130.0 74172.0 51226.0 61755.0 True False 62084.72813433218 71815.68588363947 62540.52652759029 60069.85927312668 64630.60295729801 71628.3207415121 55680.470948065304 62710.4217029992 53933.70178004829 59592.97624675909 1.0418128451456323 1.2051031917967865 1.0494613705586067 1.0080023361208366 1.0845339002650147 1.2019591108340983 0.9343462007587419 1.0523122967265734 0.9050345389148344 1.0 15.862854681191553 -7.281775990018972 24.989026877065047 0.9772826140135238 1.0963508750564068 0.43349864078967526 0.07021905597363634 862.9419481111195 1060353.1753084944 0.02938233188634822 0.019837199471662178 5.226657115248182e-08 7.281775990018972 0.11906826104288304 GT(ph)PPPVFTPPLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GTPPPVFTPPLPK 13 0 Q6NZY4-2;Q6NZY4 Q6NZY4-2 ZCCHC8 Zinc finger CCHC domain-containing protein 8 1 GT(1)PPPVFTPPLPK;GT(1)PPPVFTPPLPK;GT(1)PPPVFTPPLPK 141.34 0.00018767 18035600.0 95502.1 105760.7 96610.5 116821.3 121236.0 106379.0 120248.4 98462.7 101122.8 82030.7 True False 111668.71927754492 116259.9233478838 98914.06071736163 110276.18130076479 97480.67609990787 100800.2979704733 108857.60102897494 95878.15845485411 102601.52964445794 96902.21655533601 1.152385603210392 1.199765366373158 1.0207615907410823 1.1380150549785575 1.0059695181919965 1.0402269582028734 1.1233757585597828 0.9894320466870115 1.0588150951724344 1.0 16.564242045982553 -5.259630733796364 24.99427817977039 1.050957406173718 1.176075492957187 0.5306822020992661 0.04841537678816878 114.1243504059565 1577087.3923076724 0.011989927478018317 0.028535546061277763 5.500083289512187e-06 5.259630733796364 0.12511808678346914 GT(ph)PPPVFTPPLPK ddPTM_PC-9_Lapatinib_30min_R1 2 GTPPPVFTPPLPK 13 0 Q6NZY4-2;Q6NZY4 Q6NZY4-2 ZCCHC8 Zinc finger CCHC domain-containing protein 8 1 GT(1)PPPVFTPPLPK;GT(1)PPPVFTPPLPK 130.15 0.00020534 17381300.0 88828.0 89798.0 89363.0 74702.0 94217.0 80352.0 77601.0 78747.0 99142.0 66306.0 True False 87561.29643093972 89590.07824817277 82015.91909115558 80195.83427856663 88675.34129774888 76915.5322696606 81618.80007539094 82405.87310005711 87975.58394845697 77766.90375280855 1.1259455141645325 1.1520334991469585 1.0546378360626654 1.0312334734770814 1.140270950989821 0.9890522646259117 1.049531306207408 1.0596522315199033 1.1312728127648999 1.0 16.246868679355124 -5.265461237584424 24.856189060927676 1.0584533140345733 1.1389895102807872 0.33428114138151577 0.04626760223676548 322.7933617704021 1994963.0400956648 0.011706497052615086 0.025914701664179304 5.426736848345188e-06 5.265461237584424 0.08053619624621389 GT(ph)PSQSPVVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTPSQSPVVGR 11 0 P52594-2;P52594-3;P52594;P52594-4;C9J2I0;B8ZZY2 P52594-2 AGFG1 Arf-GAP domain and FG repeat-containing protein 1 1 GT(0.705)PS(0.225)QS(0.07)PVVGR 92.792 0.018226 4631700.0 13941.0 19198.0 22444.0 18102.0 20258.0 16645.0 16175.0 16386.0 13731.0 15582.0 True False 16300.935952698994 21103.850564838067 22979.150079343992 17087.803627475838 16288.590323269787 15772.106898152153 14642.78690314109 15955.88486240211 13931.789898500136 18406.893252955873 0.8855886611979621 1.146518876098176 1.2483991602251445 0.9283371937158266 0.8849179543459395 0.856858714906677 0.7955056131370608 0.8668429073352633 0.7568789424181018 1.0 14.167958526238362 -5.950138934379287 6.890797912763004 0.8549080406176923 1.0989342267974567 0.5074380802368879 0.10268679847837235 0.15878217244306275 17.09722436753955 0.029002772962873756 0.04308962757574955 1.1216595687717693e-06 5.950138934379287 0.24402618617976435 GT(ph)QSIPNDSPAR ddPTM_PC-9_Lapatinib_30min_R1 1 GTQSIPNDSPAR 12 0 J3QRX6;H9KV77;Q9NQ92 J3QRX6 COPRS Coordinator of PRMT5 and differentiation stimulator 1 GT(0.619)QS(0.375)IPNDS(0.006)PAR 81.789 0.031346 3457100.0 16127.0 16753.0 23051.0 13526.0 20976.0 18856.0 20295.0 15412.0 21470.0 19807.0 True False 15897.026022670407 16714.209457801244 21155.835759433172 14520.747161413281 19742.23292040272 18049.572835482868 21345.775795802343 16128.097784272175 19051.822510877013 23230.61355883148 0.68431365286204 0.7194906589734509 0.9106877743825432 0.6250694638193486 0.8498369132784873 0.7769735736756312 0.9188640559038276 0.6942605172019155 0.8201170607323097 1.0 14.503739638155656 -14.522878745276477 0.16195710271295324 1.8114171381096402 0.7227635163664152 0.37509987305155634 0.09063135273370052 146.99758349682241 1.3541260399792026 38.44730932459526 0.3622080112220465 3.0000000000266653e-15 14.522878745276477 -1.088653621743225 GT(ph)QY(ph)ET(ph)NS(ph)MDFK ddPTM_PC-9_Lapatinib_30min_R1 1 GTQYETNSMDFK 12 0 A0A087WX99;P55283 A0A087WX99 CDH4 Cadherin-4 4 GT(1)QY(1)ET(1)NS(1)MDFK 49.06 0.040465 0.0 9384.1 11160.0 9320.4 8898.8 12856.0 10748.0 10635.0 13189.0 9976.0 8674.1 True False 9250.281013166827 11134.159705668362 8554.112689784437 9553.24743752658 12099.835355868483 10288.333094811718 11185.628262545346 13801.809088811688 8852.397828062843 10173.406627488266 0.9092609144485408 1.094437695588041 0.840830707255076 0.9390411478996589 1.1893592578099708 1.0112967535390676 1.0994968226593917 1.3566556016270477 0.8701507913921288 1.0 13.312515234912887 -6.241570466129253 24.1173542947002 1.1024163423764872 0.9489985292235629 0.20764278787685808 0.13396844148888237 775.4428924156861 941249.534559839 0.0382198980912752 0.04926556190570235 5.733628284375147e-07 6.241570466129253 -0.15341781315292435 GT(ph)SPRPPEGGLGYSQLGDDDLK ddPTM_PC-9_AZD4547_30min_R2 3 GTSPRPPEGGLGYSQLGDDDLK 22 1 P21127;P21127-8;A0A0D9SEN2;A0A0D9SER5;A0A0D9SEI3;P21127-9;P21127-2;P21127-3;P21127-6;P21127-10;P21127-5;P21127-4;P21127-12;Q9UQ88-8;Q5QPR4;Q5QPR3;Q9UQ88-4;Q9UQ88-3;Q9UQ88-2;Q9UQ88;Q9UQ88-5;Q9UQ88-10 P21127;Q5QPR4 CDK11B;CDK11A Cyclin-dependent kinase 11B;Cyclin-dependent kinase 11A 1 GT(0.541)S(0.459)PRPPEGGLGYSQLGDDDLK;GT(0.492)S(0.492)PRPPEGGLGY(0.006)S(0.009)QLGDDDLK;GT(0.524)S(0.473)PRPPEGGLGY(0.002)S(0.001)QLGDDDLK 73.21300000000001 0.00084306 32058500.0 82155.0 117698.0 94290.0 89654.0 96613.0 132946.0 122573.0 135115.0 116940.0 112554.0 True False 108278.58106984358 155741.5767901646 93039.65299200846 68985.65544049219 83199.95261177127 124632.86560350069 133481.75954463537 114236.08138382056 123121.20966225825 108613.51871877145 0.996916243457731 1.4339060056917952 0.8566120874226737 0.635147965504312 0.7660183888084642 1.1474894384575411 1.22896082475934 1.0517666928700413 1.1335716871584924 1.0 16.728844155615214 -6.80599494122222 24.992965814259072 1.1228810631698485 0.943969953469188 0.15561932252985944 0.20239558742629757 289.87952714525727 162602.77423265498 0.08003822491357757 0.07058741605820312 1.5631658507070146e-07 6.80599494122222 -0.1789111097006605 GT(ph)SPRPPEGGLGYSQLGDDDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GTSPRPPEGGLGYSQLGDDDLK 22 1 P21127;P21127-8;A0A0D9SEN2;A0A0D9SER5;A0A0D9SEI3;P21127-9;P21127-2;P21127-3;P21127-6;P21127-10;P21127-5;P21127-4;P21127-12;Q9UQ88-8;Q5QPR4;Q5QPR3;Q9UQ88-4;Q9UQ88-3;Q9UQ88-2;Q9UQ88;Q9UQ88-5;Q9UQ88-10 P21127;Q5QPR4 CDK11B;CDK11A Cyclin-dependent kinase 11B;Cyclin-dependent kinase 11A 1 GT(0.498)S(0.498)PRPPEGGLGY(0.002)S(0.003)QLGDDDLK;GT(0.5)S(0.5)PRPPEGGLGYSQLGDDDLK;GT(0.499)S(0.499)PRPPEGGLGY(0.002)S(0.001)QLGDDDLK;GT(0.499)S(0.499)PRPPEGGLGY(0.001)S(0.001)QLGDDDLK 55.621 0.009299 38501500.0 86128.0 160089.0 105408.0 90144.0 101795.0 78940.0 107956.0 73073.0 67197.0 61994.0 True False 100707.76929445929 175981.57792865718 107921.32648206624 85093.52393079124 81849.00049152196 74800.24743407218 97729.62614624423 71154.91117724335 68179.62900076562 73233.02145576589 1.3751688417674894 2.4030358768544504 1.4736702697327972 1.161955662066863 1.1176515575143964 1.021400536904693 1.334502171336393 0.9716233164054585 0.9309957126642301 1.0 16.160206699482607 -5.5723346595374785 3.5721588558738975 1.0869958141182041 1.904137351741317 0.6141544798077613 0.2571051949499491 0.13145218560468902 3.4515949346315344 0.06688490671707907 0.12985733624233184 2.677104601002638e-06 5.5723346595374785 0.8171415376231128 GT(ph)SPRPPEGGLGYSQLGDDDLK ddPTM_PC-9_Lapatinib_30min_R1 4 GTSPRPPEGGLGYSQLGDDDLK 22 1 P21127;P21127-8;A0A0D9SEN2;A0A0D9SER5;A0A0D9SEI3;P21127-9;P21127-2;P21127-3;P21127-6;P21127-10;P21127-5;P21127-4;P21127-12;Q9UQ88-8;Q5QPR4;Q5QPR3;Q9UQ88-4;Q9UQ88-3;Q9UQ88-2;Q9UQ88;Q9UQ88-5;Q9UQ88-10 P21127;Q5QPR4 CDK11B;CDK11A Cyclin-dependent kinase 11B;Cyclin-dependent kinase 11A 1 GT(0.547)S(0.453)PRPPEGGLGYSQLGDDDLK;GT(0.547)S(0.453)PRPPEGGLGYSQLGDDDLK;GT(0.539)S(0.461)PRPPEGGLGYSQLGDDDLK;GT(0.5)S(0.5)PRPPEGGLGYSQLGDDDLK 101.86 5.3371999999999997e-05 54018000.0 109971.0 184122.0 129325.0 147298.0 183939.0 159226.0 192746.0 193324.0 139381.0 148092.0 True False 108402.79337378834 183695.67682142224 118692.39770893622 158130.78629172375 173120.0696579881 152416.27515393464 202725.44476657876 202306.53880395973 123682.44403300178 173689.5048798135 0.6241182704090206 1.0576095369062894 0.68335964105066 0.910422229605319 0.9967215335076265 0.8775215017130763 1.167171527760742 1.1647597184639804 0.7120893350383221 1.0 17.406151056836933 -5.997859678532238 6.414936568680517 0.9947609149211736 0.8117551594062472 0.22403385640868823 0.16263982137564975 0.22773413455239416 44.38893159586407 0.04579997161296596 0.06509707409193707 1.0049404362139866e-06 5.997859678532238 -0.18300575551492637 GTAQYS(ph)SQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTAQYSSQK 9 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 GTAQYS(0.976)S(0.024)QK 165.63 0.00077598 19345000.0 70570.0 107730.0 126190.0 88872.0 207240.0 151460.0 88587.0 113710.0 141720.0 150000.0 True False 82516.10717896611 118424.72243723314 129198.84817824 83892.78996691172 166632.8096847877 143517.17096990856 80195.39804566065 110725.23298570412 143792.3868921013 177193.8126006534 0.46568277959532905 0.6683344113382234 0.7291385984758906 0.47345214110824074 0.9403985796069115 0.8099445960528949 0.45258576960810276 0.6248820506800011 0.8114977875450436 1.0 17.434968701996766 -14.522878743584842 0.20201496909853361 2.5319707026125675 0.6136415102625677 0.3279380253418567 0.15275243776483644 186.6405505749459 1.8447631262560584 115.46172842919368 0.37064764977364095 3.000000011712068e-15 14.522878743584842 -1.9183291923499999 GTAQYS(ph)SQK ddPTM_PC-9_Lapatinib_30min_R1 1 GTAQYSSQK 9 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 GTAQYS(0.567)S(0.433)QK 144.17 0.00056359 32635000.0 121740.0 219580.0 145980.0 132780.0 172730.0 111610.0 129530.0 132390.0 179150.0 94547.0 True False 120003.9652756185 219071.57600095545 133978.08789909547 142545.08414109497 162570.36100024587 106836.70047561754 136236.42960484244 138541.32271345623 158972.24046686626 110889.32297404147 1.082195851296799 1.9755876411314983 1.2082144998798392 1.2854716785895062 1.4660596407311697 0.9634534471874031 1.2285802271219077 1.2493657549508885 1.4336117869894536 1.0 16.75876093611359 GTAQYSS(ph)QK ddPTM_PC-9_AZD4547_30min_R2 4 GTAQYSSQK 9 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 GTAQYS(0.017)S(0.983)QK;GTAQYS(0.019)S(0.981)QK;GTAQYS(0.169)S(0.831)QK;GTAQYS(0.004)S(0.996)QK 167.11 0.00014367 55585000.0 346075.0 356816.0 335456.0 371474.0 391238.0 451134.0 364977.0 366582.0 464714.0 512672.0 True False 456119.65119281964 472149.794082816 331007.634256943 285836.4085160884 336921.35695945856 422924.51966339437 397459.24594586366 309935.1751163356 489277.8333075659 494723.509325213 0.9219688221708975 0.9543710480361307 0.6690760152239922 0.5777700132058816 0.6810296066564706 0.8548704714684974 0.8033967225207982 0.6264815988613059 0.9889924858734229 1.0 18.916262932617443 -8.287883626392318 22.4880515135251 0.9944968904188984 0.7602469136774405 0.3828004563050642 0.11852964286075889 281.9204372557323 239735.71570603378 0.12439832566936214 0.0321913826021624 5.1536672381757526e-09 8.287883626392318 -0.23424997674145798 GTAQYSS(ph)QK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GTAQYSSQK 9 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 GTAQYS(0.079)S(0.921)QK;GTAQYS(0.079)S(0.921)QK;GTAQYS(0.061)S(0.939)QK;GTAQYS(0.049)S(0.951)QK;GTAQYS(0.044)S(0.956)QK 173.04 0.0008775 44183400.0 155378.0 232163.0 246234.0 179899.0 431853.0 335967.0 207151.0 241675.0 311175.0 303770.0 True False 181680.42654461396 255210.60832818455 252105.1524076454 169819.84227042727 347234.5047327 318348.29908389866 187528.15763663556 235331.28732582933 315725.3456897373 358841.0963580033 0.5062977133571058 0.711207860299172 0.7025537346929985 0.4732452441874269 0.9676553445435808 0.8871567451858792 0.5225938710474377 0.6558091860555667 0.8798472329232576 1.0 18.452985599132916 -14.522878743200547 0.08867053403131946 1.942467887033884 0.45574477268401276 0.3211034025720868 0.15240262017317827 306.6663483707429 1.887282404919249 55.18114226085271 3.9936081835599806 3.0000000143666853e-15 14.522878743200547 -1.4867231143498714 GTAQYSS(ph)QK ddPTM_PC-9_Lapatinib_30min_R1 3 GTAQYSSQK 9 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 GTAQYS(0.061)S(0.939)QK;GTAQYS(0.105)S(0.895)QK;GTAQYS(0.078)S(0.922)QK 150.09 0.00023415 44975000.0 182163.0 313882.0 210050.0 200875.0 240243.0 140198.0 233506.0 216817.0 268183.0 161496.0 True False 179565.32221539682 313155.2255138523 192780.49981644793 215648.01759935624 226112.37907591078 134202.05835750027 245595.79812636733 226891.1093493726 237977.4064478126 189410.3684201063 0.9480226648264921 1.6533161733748587 1.0177927503359625 1.1385227714728672 1.193769807650659 0.7085254069082654 1.2966333373136336 1.1978811468553567 1.256411718285591 1.0 17.531155781266577 GTAQYSS(ph)QKSVEER ddPTM_PC-9_Lapatinib_30min_R1 1 GTAQYSSQKSVEER 14 1 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 GTAQYS(0.013)S(0.85)QKS(0.137)VEER 94.45 0.016616 7076100.0 24534.0 8200.8 11176.0 8070.4 10997.0 7172.3 6384.5 5461.2 14824.0 8150.4 True False 24184.140661015434 8181.811551455648 10257.152420607577 8663.924138065187 10350.178080933862 6865.557448447909 6715.05817040158 5714.947289090785 13154.36501635962 9559.185780274656 2.5299372997770706 0.8559109258383476 1.07301528146604 0.9063454081981712 1.0827468279036292 0.7182157148378643 0.7024717716291358 0.5978487520227462 1.376096805598611 1.0 13.222672024124826 -4.760348979275445 24.99976484468537 0.9068311008571248 2.5299392266849967 0.8336559870118909 0.2151409143551686 10.192567862136364 233579.99670677623 0.05308060849213758 0.3166572721806022 1.736404972011172e-05 4.760348979275445 1.623108125827872 GTAQYSSQKS(ph)VEER ddPTM_PC-9_AZD4547_30min_R2 1 GTAQYSSQKSVEER 14 1 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 GTAQYSS(0.001)QKS(0.998)VEER 73.735 0.0093404 48673000.0 34640.0 24695.0 45441.0 105310.0 71266.0 38489.0 39234.0 71210.0 42486.0 60543.0 True False 45654.79944324008 32677.17581295442 44838.42264937805 81032.40652328101 61371.94604070354 36082.276745544266 42725.74999367092 60206.13074301055 44731.72322311192 58423.407997855014 0.7814470433651572 0.5593164954388513 0.7674735895417856 1.3869852735440575 1.050468436263711 0.617599657090682 0.7313121821862836 1.0305138437870827 0.7656472765976647 1.0 15.834258896535433 -5.532133650244071 24.99527330426245 0.9358435609407362 0.6686349619960257 0.22623790750427963 0.20651933403266826 293.8496075516971 793614.6401355526 0.0602227056598697 0.10448225094976771 2.9367457556348286e-06 5.532133650244071 -0.2672085989447105 GTAQYSSQKS(ph)VEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GTAQYSSQKSVEER 14 1 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 GTAQYS(0.001)S(0.001)QKS(0.998)VEER;GTAQY(0.002)S(0.296)S(0.296)QKS(0.405)VEER;GTAQYS(0.002)S(0.005)QKS(0.993)VEER 96.414 0.0067007 63677400.0 74029.9 21990.850000000002 53630.7 100139.0 133104.0 154106.0 132453.8 269001.0 160146.0 116699.1 True False 86561.69991282618 24173.956255535424 54909.45928356235 94528.53648501825 107023.2266950588 146024.41007189173 119906.8171815315 261940.00878011898 162487.83228353414 137855.7230404328 0.6279151710476164 0.1753569291312284 0.3983110608143379 0.6857062906071244 0.776342282602726 1.0592553348623988 0.8697993419276695 1.900102534758695 1.178680352906907 1.0 17.072799636095134 -6.659651847697761 0.9386767904325097 1.3489628102551985 0.3752872979935682 0.6238345450767673 0.27533990790532437 0.3349332255839513 0.6421149549979195 0.15513576052790173 0.15880385431550617 2.18951614687736e-07 6.659651847697761 -0.9736755122616303 GTDDLNPVTSTPAKPS(ph)SPPPEFSFNTPGK ddPTM_PC-9_AZD4547_30min_R2 1 GTDDLNPVTSTPAKPSSPPPEFSFNTPGK 29 1 B5MCR8;Q6NXT4-4;Q6NXT4-3;Q6NXT4;Q6NXT4-2 B5MCR8 SLC30A6 Zinc transporter 6 1 GTDDLNPVT(0.002)S(0.002)T(0.002)PAKPS(0.973)S(0.022)PPPEFSFNTPGK 98.133 5.0824e-11 10494000.0 63160.0 57590.0 72832.0 76154.0 60011.0 48921.0 68780.0 60509.0 63434.0 42629.0 True False 83243.56619038794 76204.84126616915 71866.20009241658 58597.87186757135 51679.508515261965 45861.96213642264 74901.28675548466 51158.7244084935 66786.99173692225 41136.57168525777 2.0235902696825896 1.8524840098300877 1.7470148130543284 1.4244714488098977 1.2562910908247247 1.114870789119705 1.8207955521565073 1.2436312097156945 1.6235429692080272 1.0 15.328133944467925 -5.603717792561173 2.065565684023947 1.3636507178085335 1.948076182834379 0.5383239717667745 0.22592578657377752 0.25903371442723455 2.20996259468346 0.06538451447876077 0.15089081431421467 2.490475119870425e-06 5.603717792561173 0.5844254650258456 GTDDLNPVTSTPAKPS(ph)SPPPEFSFNTPGK ddPTM_PC-9_Lapatinib_30min_R1 1 GTDDLNPVTSTPAKPSSPPPEFSFNTPGK 29 1 B5MCR8;Q6NXT4-4;Q6NXT4-3;Q6NXT4;Q6NXT4-2 B5MCR8 SLC30A6 Zinc transporter 6 1 GTDDLNPVTS(0.001)T(0.001)PAKPS(0.993)S(0.004)PPPEFSFNTPGK 128.25 3.2302e-12 6999800.0 75379.0 64105.0 45974.0 37683.0 66882.0 77299.0 83338.0 72852.0 98391.0 38691.0 True False 74304.0816371845 63956.56881109947 42194.19518477206 40454.33352680295 62948.13225507115 73993.10196276997 87652.83386403431 76236.96987930148 87309.16947683757 45378.68779748316 1.637422438674078 1.4093966113900431 0.9298240480878842 0.891483105623135 1.3871739204094493 1.6305694490988314 1.931585907799119 1.6800170648286092 1.924012652513941 1.0 15.469727271163608 -6.670525837310624 3.479986560543733 1.698231541527879 1.204478764578547 0.26603477782193874 0.3167836666693879 0.2812336736229667 6.690426595308881 0.11182853415006253 0.10970822759044883 2.135375043241702e-07 6.670525837310624 -0.49375277694933195 GTDDLNPVTSTPAKPSS(ph)PPPEFSFNTPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTDDLNPVTSTPAKPSSPPPEFSFNTPGK 29 1 B5MCR8;Q6NXT4-4;Q6NXT4-3;Q6NXT4;Q6NXT4-2 B5MCR8 SLC30A6 Zinc transporter 6 1 GTDDLNPVT(0.002)S(0.001)T(0.001)PAKPS(0.205)S(0.791)PPPEFSFNTPGK 77.169 2.0355000000000002e-06 4658700.0 29255.0 27903.0 21850.0 28086.0 40211.0 34558.0 41896.0 34321.0 35649.0 35575.0 True False 34207.29368741189 30673.02543549728 22370.98686658644 26512.432476040547 32331.94320707874 32745.71764411791 37927.30757922713 33420.11011610542 36170.29918371799 42024.465888454964 0.813985209906246 0.7298849559899779 0.5323324495298878 0.6308808908223171 0.7693600031204925 0.7792060399062412 0.9025054043493884 0.7952536554494711 0.8606962258538723 1.0 15.358941863140005 -6.795190205779209 1.729326366914413 0.8726301877457324 0.6737246736399077 0.5392129855091523 0.08518718707885424 0.31005726762874514 1.9170246867029228 0.03832591570005999 0.0340788939826076 1.60254337907512e-07 6.795190205779209 -0.1989055141058247 GTDDS(ph)PKDSQEDLQER ddPTM_PC-9_Lapatinib_30min_R1 1 GTDDSPKDSQEDLQER 16 1 Q969E4;Q6IPX3-2;Q6IPX3;Q5H9L2 Q969E4 TCEAL3;TCEAL6;TCEAL5 Transcription elongation factor A protein-like 3;Transcription elongation factor A protein-like 6;Transcription elongation factor A protein-like 5 1 GT(0.016)DDS(0.982)PKDS(0.002)QEDLQER 105.63 0.005357100000000001 5192000.0 29980.0 32428.0 21880.0 24769.0 30601.0 26315.0 30063.0 27955.0 22153.0 19948.0 True False 29552.479702341327 32352.914958370377 20081.11085924246 26590.5948869618 28801.109343880784 25189.568793261107 31619.515040611263 29253.891354744912 19657.895858568165 23395.985220960774 1.263143202700644 1.3828404597120778 0.8583143932426289 1.1365452078991285 1.2310278482342982 1.0766620236489737 1.3514932045812253 1.2503808272427852 0.840225178504404 1.0 14.513973362403107 -14.522878453062587 0.08675974071579508 0.4044303180757914 1.3166766923076958 0.12651164902568213 0.1703347790797635 567.6920638185534 3.4311177493376404 61.379763269824764 4.691728604329194 3.0000020185693884e-15 14.522878453062587 0.9122463742319045 GTDTQTPAVLS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 4 GTDTQTPAVLSPSK 14 0 P46087-2;P46087;P46087-4 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 GTDTQT(0.001)PAVLS(0.984)PS(0.016)K;GTDTQT(0.067)PAVLS(0.92)PS(0.013)K;GTDT(0.001)QT(0.002)PAVLS(0.669)PS(0.329)K;GTDTQTPAVLS(0.844)PS(0.156)K 109.14 0.00061845 753682500.0 383605.0 486990.0 480015.0 426557.0 422958.0 533776.0 468733.0 537338.0 462596.0 560299.0 True False 505583.4105203271 644399.9938915033 473649.68746377045 328220.8738899553 364237.58248651423 500398.9023390997 510449.3289438583 454304.7588988604 487047.8801515483 540683.1025517427 0.9350826910148231 1.1918256569333698 0.8760208803056552 0.6070485138908978 0.673661856210232 0.9254938798299363 0.9440822665528167 0.8402421987200609 0.90080100127586 1.0 19.04442374440263 -5.426483495448723 6.986068208007527 0.8288118776349063 1.0602701531040435 0.3156597687674333 0.12790671478736523 0.28643880069769806 17.868758590971566 0.03530052766844849 0.07394631182470371 3.7455578105906994e-06 5.426483495448723 0.23145827546913722 GTDTQTPAVLS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 GTDTQTPAVLSPSK 14 0 P46087-2;P46087;P46087-4 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 GTDTQT(0.001)PAVLS(0.5)PS(0.5)K;GTDTQTPAVLS(0.995)PS(0.005)K;GTDT(0.001)QT(0.002)PAVLS(0.951)PS(0.046)K;GTDTQT(0.001)PAVLS(0.995)PS(0.004)K;GTDTQTPAVLS(0.955)PS(0.044)K;GTDTQT(0.003)PAVLS(0.953)PS(0.043)K;GTDTQTPAVLS(0.912)PS(0.088)K 128.64 2.5055e-05 627917500.0 497640.0 570517.0 527912.0 542767.0 658749.0 469828.0 592762.0 602333.0 501964.0 356999.0 True False 581880.6231619779 627154.1573444995 540499.4241974092 512357.5246643557 529671.862319263 445189.39259507565 536611.2921347588 586522.3969745666 509304.27387741127 421720.09269747074 1.3797792261688642 1.4871336893933602 1.281654428035866 1.2149232003320873 1.2559796687212474 1.0556513675871761 1.272434729638807 1.3907859908285662 1.2076832066969376 1.0 18.685926234361744 -5.4370589323607454 3.829885281558246 1.2164996080076624 1.4320110135741295 0.42192730683520674 0.1068547832367745 0.23156403735081263 6.237866110475531 0.028851291180914864 0.06351513731350034 3.655451849446278e-06 5.4370589323607454 0.21551140556646708 GTDTQTPAVLS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 5 GTDTQTPAVLSPSK 14 0 P46087-2;P46087;P46087-4 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 GTDTQT(0.018)PAVLS(0.969)PS(0.012)K;GTDTQT(0.022)PAVLS(0.947)PS(0.031)K;GTDT(0.002)QT(0.267)PAVLS(0.366)PS(0.366)K;GTDTQTPAVLS(0.916)PS(0.083)K;GTDTQTPAVLS(0.746)PS(0.254)K 173.37 0.00014516 1191643000.0 415884.1 997365.0 795659.0 815683.0 1057989.0 1025461.0 1124404.0 1171438.0 883179.0 845508.0 True False 409953.516470197 995055.6626204215 730242.9883525602 875671.0488587193 995760.1671064044 981604.423496346 1182620.137368974 1225867.2860246703 783706.0807328309 991652.931231405 0.413404230007296 1.0034313732979048 0.7363896836827439 0.8830418599896005 1.004141807829781 0.9898669106714775 1.1925746398999009 1.2361858140250994 0.7903027924897555 1.0 19.919475754319492 -4.382714659383172 0.5786784187168506 1.0602771031248306 6.450230423093401e-15 0.502238594718059 0.15899911503139894 5.068672448106685 0.9229462475619087 0.08076829757526557 3.9771677209008844 4.1427177069765556e-05 4.382714659383172 -1.0602771031248241 GTDTQTPAVLSPS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 GTDTQTPAVLSPSK 14 0 P46087-2;P46087;P46087-4 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 GTDTQTPAVLS(0.223)PS(0.777)K 148.7 0.00021695 172690000.0 64787.0 79301.0 86744.0 68299.0 70140.0 65394.0 100060.0 67999.0 82314.0 96105.0 True False 85387.91834668569 104933.49743442393 85593.71788247726 52553.72075903113 60402.27170452878 61304.902842321775 108965.14615809522 57491.317011570965 86664.94999263833 92740.39320208546 0.9207198222744388 1.1314756581392658 0.9229389150417415 0.5666756301594951 0.651304891202149 0.6610377714135377 1.1749480716633938 0.6199166838369428 0.9344897837967059 1.0 16.500910223034545 -5.527827943946516 24.96482068435185 0.7854592354568922 1.0263751622023392 0.18863907427230608 0.18732251700290545 183.78311734051812 927038.3617076125 0.05058339799395536 0.08800369409892123 2.966006210458619e-06 5.527827943946516 0.24091592674544693 GTDTQTPAVLSPS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GTDTQTPAVLSPSK 14 0 P46087-2;P46087;P46087-4 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 GTDTQTPAVLS(0.211)PS(0.789)K;GTDTQTPAVLS(0.07)PS(0.93)K;GTDTQTPAVLS(0.355)PS(0.645)K 179.81 1.0379e-18 189120600.0 130605.0 167844.0 135162.0 130567.0 150094.0 110676.0 138150.0 134182.0 105444.0 80448.0 True False 152713.8469336668 184506.44307764768 138384.77468473962 123251.75429392542 120684.15815879406 104871.95572603706 125063.43188061482 130659.8646775808 106985.91901955075 95032.58557398229 1.6069629802377627 1.9415071363496739 1.4561823594393095 1.2969420283527346 1.2699239679724612 1.1035368036408406 1.3160057797570257 1.3748953991771895 1.1257814187983224 1.0 16.536134661259304 -5.540884907912096 2.738762055031508 1.2278487089525039 1.7740809621927578 0.7380431953076616 0.13264848559517511 0.12788936657529734 1.9250825894793153 0.03578079932823737 0.07788897947641057 2.8781610531986782e-06 5.540884907912096 0.5462322532402539 GTDTQTPAVLSPS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 GTDTQTPAVLSPSK 14 0 P46087-2;P46087;P46087-4 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 GTDTQTPAVLS(0.047)PS(0.953)K 170.78 0.00025186 7189800.0 20755.0 46896.0 44369.0 45689.0 55373.0 51151.0 52339.0 52179.0 37088.0 49445.0 True False 20459.02989399916 46787.415193281624 40721.15208929288 49049.121474036 52116.06900750662 48963.39096880485 55048.85732330614 54603.42682880468 32910.75888604597 57991.5023686789 0.35279358282411116 0.8067977769541528 0.7021917078541889 0.845798426848954 0.8986845809956876 0.8443200980985429 0.9492573062400591 0.9415763447835055 0.5675100237413578 1.0 15.8235538937771 -4.5822477246351365 1.8422095186121288 0.850243966395375 4.676835865010288e-30 0.5896848805314079 0.12136012922724901 1.132952831495485 2.5635071663680344 0.03192388938183246 1.9834917985131375 2.6166900040181283e-05 4.5822477246351365 -0.850243966395375 GTDTQTPAVLSPS(ph)KTQATLKPK ddPTM_PC-9_AZD4547_30min_R2 3 GTDTQTPAVLSPSKTQATLKPK 22 2 P46087-2;P46087;P46087-4 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 GT(0.002)DT(0.002)QT(0.012)PAVLS(0.056)PS(0.527)KT(0.174)QAT(0.226)LKPK;GTDTQT(0.024)PAVLS(0.303)PS(0.54)KT(0.049)QAT(0.085)LKPK;GTDTQT(0.001)PAVLS(0.036)PS(0.944)KT(0.019)QAT(0.001)LKPK 90.765 0.00056713 335274000.0 154657.0 151315.0 195781.0 238193.0 211075.0 185270.0 154215.0 174835.0 156220.0 216463.0 True False 203834.70893456077 200224.61462389954 193184.81601896725 183281.28389516557 181770.87966970942 173685.0376119665 167939.83624595925 147818.26805861908 164477.47027054915 208884.69625620905 0.9758240435409677 0.9585413302768364 0.9248394903091177 0.877428012583366 0.8701972089269624 0.8314876136207309 0.803983438020617 0.707654848382533 0.7874079490668292 1.0 17.672347272997698 -5.98509941180495 0.9203754570598958 0.8047025203720173 0.9765661679359017 0.3675217887810336 0.07018364483256291 0.5997307085077185 1.022747545733506 0.030569450454631206 0.07011069209115818 1.034905245468909e-06 5.98509941180495 0.1718636475638844 GTDTQTPAVLSPS(ph)KTQATLKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTDTQTPAVLSPSKTQATLKPK 22 2 P46087-2;P46087;P46087-4 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 GTDTQTPAVLS(0.175)PS(0.61)KT(0.107)QAT(0.107)LKPK 53.254 0.0063507 168440000.0 61574.0 30405.0 48963.0 67865.0 72905.0 69100.0 64203.0 89019.0 82550.0 59361.0 True False 71997.26205806524 33423.407460355316 50130.46361321157 64062.74407129857 58619.78860292146 65476.27435640214 58121.22705053276 86682.34557342675 83757.13758074334 70122.67939858252 1.0267329011891781 0.4766419045452354 0.714896579012138 0.9135809501396998 0.8359604782030964 0.9337389118323635 0.8288506307662231 1.2361527870422329 1.1944372106014596 1.0 16.097593502303987 -7.303440221105192 0.9888438146278244 1.1541998426652011 0.7603419931314841 0.42709374529235966 0.16005338955753964 0.49641822921659295 0.9346703780624481 0.12044893452130137 0.06647310892130263 4.9723281111863983e-08 7.303440221105192 -0.39385784953371705 GTDTQTPAVLSPS(ph)KTQATLKPK ddPTM_PC-9_Lapatinib_30min_R1 1 GTDTQTPAVLSPSKTQATLKPK 22 2 P46087-2;P46087;P46087-4 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 GTDTQT(0.001)PAVLS(0.024)PS(0.63)KT(0.246)QAT(0.098)LKPK 46.786 0.01839 169050000.0 172040.0 136560.0 121960.0 113730.0 104990.0 107590.0 94984.0 77005.0 120770.0 93872.0 True False 169586.6780517283 136243.8037102213 111932.91957921429 122094.08359215826 98814.69461828182 102988.62650453969 99901.80675971872 80582.93342057329 107167.61083552004 110097.65012342257 1.540329678804378 1.2374814862759393 1.0166694698182415 1.1089617576332225 0.8975186528278102 0.9354298333260204 0.9073927249830126 0.7319223737312971 0.9733869044015211 1.0 16.74842415140936 -1.5228787452807453 0.5326145319565218 0.8849292069549511 27.386111522377153 0.850455352560223 0.08149763928109155 41.75252814063124 0.4036324805797406 0.040779390299494886 1256.872215023418 0.029999999999971834 1.5228787452807453 26.501182315422202 GTDTVAGLALIK ddPTM_PC-9_Lapatinib_30min_R1 2 GTDTVAGLALIK 12 0 P43490;A0A0C4DFS8 P43490 NAMPT Nicotinamide phosphoribosyltransferase 0 ; 154.35 0.00029933 8038200.0 51851.0 56843.0 58075.0 54156.0 65256.0 52451.0 53050.0 50502.0 53682.0 58381.0 False True 51111.595231691164 56711.38352592349 53300.29767598292 58138.81289912001 61417.77037823222 50207.792999252866 55796.669424356434 52848.507286615146 47635.76786347929 68472.07806220737 0.7464589461598627 0.8282410163512315 0.7784238361739105 0.849087898957886 0.8969754112389249 0.7332593725816052 0.8148820804542366 0.7718256664943323 0.6956962489177246 1.0 16.063228177061248 -11.810064613208363 2.503079523830892 2.0750209485442324 0.7946249034557599 0.5542400283657073 0.05624685632478638 15103256.71763316 6073774.92925144 89320823.33643644 0.014410019502443156 1.5485862071272147e-12 11.810064613208363 -1.2803960450884726 GTDVNVFNTILTTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTDVNVFNTILTTR 14 0 P04083 P04083 ANXA1 Annexin A1 0 117.03 0.00062663 4007000.0 11434.0 10554.0 11787.0 14404.0 15493.0 15589.0 12659.0 14514.0 14345.0 14437.0 False True 13369.550368206037 11601.731371043903 12068.046782446427 13596.990578398065 12457.257867431077 14771.485397133909 11459.847876776688 14133.022878854157 14554.768486926265 17054.313816770886 0.7839395071444433 0.6802813350153661 0.7076242944807865 0.7972757347192149 0.7304461499459948 0.8661436370783745 0.6719618273651851 0.8287066269975643 0.8534361829681698 1.0 14.057849088587135 -9.17755301831896 0.39244904748433823 1.0340236388206572 0.7289199681924972 0.6366424632376415 0.057746735556414706 1.847113376342593 0.49019685925830137 0.16206508176328147 0.042927872991206845 6.644265553002152e-10 9.17755301831896 -0.30510367062816 GTDVNVFNTILTTR ddPTM_PC-9_Lapatinib_30min_R1 2 GTDVNVFNTILTTR 14 0 P04083 P04083 ANXA1 Annexin A1 0 ; 231.69 1.3643e-20 47755000.0 92446.0 81786.0 101634.0 87238.0 102717.0 104312.0 86062.0 78147.0 98814.0 94608.0 False True 91127.70308748 81596.62954191698 93278.04483858528 93653.77353743711 96675.38800939197 99850.8189231485 90517.86925539996 81777.99490964934 87684.52676245001 110960.86674276409 0.8212598347734388 0.7353640246076936 0.8406391151830839 0.8440252522049122 0.8712566046686573 0.8998741795576314 0.8157638986837019 0.7369985230850064 0.790229288364567 1.0 16.759691436502635 -11.940082326296285 2.305546144401009 2.667801456334298 0.8179456992065182 0.5467870059560906 0.049905497057864213 2986593.254407333 344916.60699126817 26233393.5327493 0.013839911043721922 1.1479359943322293e-12 11.940082326296285 -1.84985575712778 GTEAPAVVT(ph)EEEDDDEETAPPVIAPRPDHTK ddPTM_PC-9_AZD4547_30min_R2 4 GTEAPAVVTEEEDDDEETAPPVIAPRPDHTK 31 1 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 GTEAPAVVT(1)EEEDDDEETAPPVIAPRPDHTK;GTEAPAVVT(1)EEEDDDEETAPPVIAPRPDHTK;GTEAPAVVT(1)EEEDDDEETAPPVIAPRPDHTK;GTEAPAVVT(0.99)EEEDDDEET(0.009)APPVIAPRPDHTK 115.45 2.7973999999999996e-17 136481000.0 285345.0 258635.0 350835.0 485811.0 425574.0 380322.0 340653.0 424107.0 352193.0 385381.0 True False 376078.7744552935 342233.7058669147 346182.69866848306 373814.77965512895 366490.3960419598 356540.4052175667 370970.4570676957 358571.00815933093 370809.2029637401 371888.9284908472 1.0112663906974833 0.9202578502557859 0.930876592840013 1.0051785654714085 0.985483481665359 0.9587282059308248 0.9975302533827003 0.9641884463042195 0.99709664514217 1.0 18.504512272536992 -5.7607179451061254 24.999978034568343 0.9846061319707154 0.9507460366959279 0.23615320681697205 0.026566146218429176 26.643765148066308 923231.1203999673 0.007167612186670235 0.011529505047100723 1.734930391844457e-06 5.7607179451061254 -0.033860095274787505 GTEAPAVVT(ph)EEEDDDEETAPPVIAPRPDHTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GTEAPAVVTEEEDDDEETAPPVIAPRPDHTK 31 1 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 GTEAPAVVT(1)EEEDDDEETAPPVIAPRPDHTK;GTEAPAVVT(1)EEEDDDEETAPPVIAPRPDHTK;GTEAPAVVT(1)EEEDDDEETAPPVIAPRPDHTK;GTEAPAVVT(1)EEEDDDEETAPPVIAPRPDHTK 127.94 3.2123e-17 86606900.0 330788.0 324752.0 349234.0 402577.0 426818.0 407359.0 422725.0 401101.0 375425.0 309333.0 True False 386783.8750391936 356991.232348802 357561.06303732103 380021.9158622438 343186.07683865 385996.37692546524 382681.42773603095 390572.52375163854 380914.88039067824 365412.62422131974 1.0584852558485498 0.9769537467665125 0.9785131638494152 1.0399802597736076 0.9391741119233806 1.0563301630533666 1.0472583659404497 1.068853394389243 1.0424239753686486 1.0 18.479166951278188 -6.859347481890012 20.29039852826607 1.0475498204231 0.9984659251502683 0.27759610123305944 0.035385954189067176 4.370863117530675 896.7628523675888 0.011829058873498347 0.010432252176776373 1.3824598210938927e-07 6.859347481890012 -0.049083895272831635 GTEAPAVVT(ph)EEEDDDEETAPPVIAPRPDHTK ddPTM_PC-9_Lapatinib_30min_R1 4 GTEAPAVVTEEEDDDEETAPPVIAPRPDHTK 31 1 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 GTEAPAVVT(1)EEEDDDEETAPPVIAPRPDHTK;GTEAPAVVT(1)EEEDDDEETAPPVIAPRPDHTK;GTEAPAVVT(1)EEEDDDEETAPPVIAPRPDHTK;GTEAPAVVT(1)EEEDDDEETAPPVIAPRPDHTK 129.22 5.006e-18 159830000.0 798510.0 637282.0 749570.0 644206.0 688490.0 695600.0 591943.0 579306.0 764370.0 565572.0 True False 787123.1009711984 635806.4126834879 687943.2480238738 691583.058248218 647994.3718234206 665850.8095227982 622590.912140656 606222.6716205266 678278.6014270647 663330.3666226815 1.186623047243868 0.9585064165246486 1.037105012282956 1.0425921879159308 0.976880306449193 1.0037996796572866 0.9385834622807204 0.9139076124421737 1.0225351281300321 1.0 19.339368047007646 -4.756378464486096 24.999135482452512 0.9873311722292234 1.1866233545610636 0.6900680650987849 0.03988696438581085 96.54308416800643 476834.9124351594 0.010611238864996032 0.08621894003833004 1.752352754266417e-05 4.756378464486096 0.1992921823318402 GTEASPPQNNSGS(ph)SSPVFTFR ddPTM_PC-9_Lapatinib_30min_R1 1 GTEASPPQNNSGSSSPVFTFR 21 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 GTEASPPQNNS(0.172)GS(0.276)S(0.276)S(0.276)PVFTFR 122.13 1.4906e-06 7119900.0 23635.0 17642.0 22500.0 14556.0 22299.0 20484.0 24876.0 19840.0 23187.0 16993.0 True False 23297.96056587183 17601.15103292125 20650.136852511656 15626.496797392541 20987.41666152079 19607.947070536215 26163.957560797193 20761.838829480927 20575.43589006545 19930.21740825078 1.1689767396228632 0.8831389378439326 1.0361220065749428 0.7840605286585298 1.0530450436949246 0.9838300641125394 1.3127783317589776 1.0417266607882496 1.03237388075594 1.0 14.282669827413049 -7.0474582805677874 24.99959918248333 1.107069434739148 0.9758110268927462 0.15763036907406336 0.12486031712664779 657.4517122493927 346323.7672162184 0.04624274942291928 0.03582053977155483 8.964823001829494e-08 7.0474582805677874 -0.13125840784640186 GTEASPPQNNSGSS(ph)SPVFTFR ddPTM_PC-9_AZD4547_30min_R2 1 GTEASPPQNNSGSSSPVFTFR 21 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 GTEASPPQNNS(0.027)GS(0.012)S(0.943)S(0.018)PVFTFR 183.39 6.4242000000000005e-15 6373000.0 21597.0 23388.0 40727.0 59246.0 43016.0 35973.0 38519.0 52798.0 47507.0 40479.0 True False 28464.396754493537 30947.713622732485 40186.933369450926 45587.75004157539 37043.97091020828 33723.602623281055 41947.116378809464 44639.28227734124 50018.12303253726 39061.84253084869 0.7287008218317933 0.7922748036857669 1.0288028102543731 1.167066044198323 0.9483416170384994 0.8633387581921714 1.073864253732582 1.1427848607522244 1.280485501753686 1.0 15.25347238170359 -5.241217778105165 3.5212365053790937 1.0633871339301082 0.743583727241733 0.5500574835996238 0.1104826352234315 0.18904790992247067 5.014062882196045 0.03197109271888126 0.09104085228969999 5.738286421740964e-06 5.241217778105165 -0.31980340668837515 GTEASPPQNNSGSS(ph)SPVFTFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTEASPPQNNSGSSSPVFTFR 21 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 GTEASPPQNNSGS(0.001)S(0.91)S(0.089)PVFTFR 161.14 4.0924e-06 5304200.0 12914.0 12619.0 14254.0 15908.0 20599.0 16167.0 17504.0 16902.0 14557.0 13225.0 True False 15100.085136873604 13871.73092393435 14593.869418596028 15016.726334431854 16562.773821158764 15319.174059623068 15845.89440201432 16458.340409149303 14769.868585861657 15622.587810957593 0.966554665564593 0.8879278575220936 0.9341518572460814 0.9612188784689825 1.0601811954317664 0.9805785216248417 1.014293828510287 1.0534964250676522 0.9454175431487833 1.0 13.931345828727547 -6.002089498802733 4.23819417943747 1.0108564345063469 0.9270520596914799 0.5016154127391852 0.03579901990733775 0.1553282355926862 6.738424094402827 0.010084481322533497 0.014438116737042343 9.952003067228965e-07 6.002089498802733 -0.08380437481486702 GTEASPPQNNSGSSS(ph)PVFTFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GTEASPPQNNSGSSSPVFTFR 21 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 GTEASPPQNNSGS(0.001)S(0.12)S(0.871)PVFT(0.008)FR;GTEASPPQNNSGS(0.003)S(0.081)S(0.917)PVFTFR 251.38 4.6888999999999986e-144 5369200.0 25357.0 28437.0 37575.0 35816.0 48307.0 40541.0 35034.0 40659.0 35167.0 33013.0 True False 29649.43927642122 31260.037426414205 38470.93050398104 33809.345637038685 38841.59012470102 38414.958591648356 31715.325895804915 39591.74433177151 35681.250845572366 38997.9955692358 0.760281107878546 0.8015806189555597 0.9864848165255309 0.8669508558975717 0.9959893978587412 0.9850495655205577 0.8132552823003053 1.015225109749079 0.9149508923407361 1.0 15.25111235335412 -5.155371766826246 4.756763527213456 0.9430231898489353 0.7706321707004775 0.5349974776849515 0.062236658048483856 0.16239156991044004 5.732389319873741 0.015304117606604889 0.04400170576225733 6.992431702724689e-06 5.155371766826246 -0.17239101914845778 GTEASPPQNNSGSSS(ph)PVFTFR ddPTM_PC-9_Lapatinib_30min_R1 1 GTEASPPQNNSGSSSPVFTFR 21 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 GTEASPPQNNSGS(0.008)S(0.228)S(0.764)PVFTFR 236.66 3.7951e-51 7283900.0 23286.0 21320.0 18482.0 16747.0 24562.0 23968.0 25364.0 21928.0 23585.0 15811.0 True False 22953.937369870604 21270.634849896895 16962.481302583146 17978.630246354285 23117.31145074998 22942.94451213688 26677.223812994867 22946.85493209966 20928.60893893966 18543.91028316679 1.2378153808642511 1.1470415098591846 0.9147197674905069 0.9695166753839595 1.2466255011886402 1.237222579369536 1.4385975452659021 1.2374334529071593 1.1285974004057588 1.0 14.178657871156199 -6.280680881395226 23.59815616203023 1.2389341815799828 1.0620743814008782 0.21479565423826275 0.13325846366923433 536.2314270531901 657642.6291848294 0.04294239381538538 0.04878475443284889 5.239853183922177e-07 6.280680881395226 -0.17685980017910463 GTEASS(ph)GTEAATGLEGEEK ddPTM_PC-9_Lapatinib_30min_R1 1 GTEASSGTEAATGLEGEEK 19 0 Q8IY81 Q8IY81 FTSJ3 pre-rRNA processing protein FTSJ3 1 GTEAS(0.02)S(0.955)GT(0.025)EAATGLEGEEK 181.41 4.7859999999999995e-37 0.0 9276.6 14553.0 11237.0 10065.0 14430.0 12150.0 14829.0 15212.0 11607.0 13277.0 True False 9144.313982879905 14519.303422633653 10313.137236074386 10805.213675855735 13581.255770471536 11630.372823033347 15596.773061145748 15918.805054136279 10299.697432871428 15571.911759509543 0.5872312997982154 0.932403397018155 0.6622910144463349 0.6938912731288209 0.8721636739418112 0.7468815006565167 1.0015965478112232 1.0222768597705991 0.6614279346003582 1.0 13.926658454130312 -6.850315060318157 1.6128837563604739 0.9159219262596213 0.7382955058415854 0.26340925625614897 0.13490011014107509 0.5409851538014723 2.905964689575562 0.05944753989819998 0.050350304754863434 1.4115131863591245e-07 6.850315060318157 -0.1776264204180359 GTEDITSPHGIPLDLLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTEDITSPHGIPLDLLDR 18 0 Q9Y265;H7C4G5;E7ETR0;Q9Y265-2;J3QLR1 Q9Y265 RUVBL1 RuvB-like 1 0 90.706 0.0037408999999999997 0.0 7876.1 10167.0 14059.0 12019.0 14888.0 14298.0 13639.0 12631.0 10114.0 8232.3 False True 9209.368169934192 11176.312568637803 14394.219879054415 11345.614396123747 11970.803274402237 13548.187709809523 12347.015182191106 12299.449633650751 10261.898116191853 9724.750823149056 0.9470029965201748 1.1492646723691275 1.4801633626221076 1.1666740467134997 1.2309624680466484 1.3931655377286436 1.2696484883499475 1.2647573040506923 1.0552350700610402 1.0 13.247445569124652 -8.348131474177817 3.9738005534725205 1.0053568731457054 1.2467098504077512 0.2789791752393056 0.13540103450322918 0.29758093890121556 8.159993115055558 0.1316809343951722 0.035150148788233256 4.4860956158569004e-09 8.348131474177817 0.24135297726204574 GTEDITSPHGIPLDLLDR ddPTM_PC-9_Lapatinib_30min_R1 2 GTEDITSPHGIPLDLLDR 18 0 Q9Y265;H7C4G5;E7ETR0;Q9Y265-2;J3QLR1 Q9Y265 RUVBL1 RuvB-like 1 0 ; 172.91 2.8426e-08 4917200.0 43772.0 38006.0 53840.0 45640.0 48341.0 50791.0 39945.0 41336.0 56702.0 37258.0 False True 43147.803253198304 37917.99944208167 49413.48302841017 48996.51785057682 45497.67742206268 48618.78732960386 42013.15664761394 43256.62146448707 50315.62366146946 43697.99565683561 0.9874092073247932 0.8677285736365398 1.130795183753022 1.121253208850836 1.041184538058911 1.1126090933646404 0.9614435631681402 0.9898994407932417 1.1514400810646488 1.0 15.41527948714123 -5.2592797967442095 24.978118335416628 1.062580898973388 0.9275688899912691 0.3938391591725231 0.067484567523384 186.39219946419146 2155809.244516607 0.017552127760210652 0.042154961266307855 5.504529496316485e-06 5.2592797967442095 -0.13501200898211896 GTENGVNGTLTSNVADS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 GTENGVNGTLTSNVADSPR 19 0 G3XAN4;Q15629-2;Q15629 G3XAN4 TRAM1 Translocating chain-associated membrane protein 1 1 GTENGVNGTLTSNVADS(1)PR 184.34 8.445999999999999e-11 4169500.0 8317.7 8345.7 8230.1 3299.2 5940.2 5758.1 4646.3 3952.6 7729.1 2624.3 True False 8199.088072720631 8326.37604440828 7553.452947104723 3541.8341738085664 5590.809114882539 5511.839485786693 4886.862679479496 4136.25222567572 6858.567366968777 3077.906758340056 2.6638519995785956 2.705207369211786 2.454087644675231 1.1507282227479532 1.8164322553740109 1.7907753283466197 1.5877227814773138 1.3438523485053329 2.228322007606126 1.0 11.587733812196326 -5.634863209076296 5.935253529931867 1.5980608738056368 2.6578512251507975 0.6760173544252486 0.33369898330095177 0.11491436801013037 5.518791124076663 0.08651819766020412 0.15150656818345187 2.318124681079075e-06 5.634863209076296 1.0597903513451608 GTENTFPS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 GTENTFPSPK 10 0 J3QSD2;J3QRZ1;A6NIZ0;Q9GZM8-3;Q9GZM8;Q9GZM8-2 J3QSD2 NDEL1 Nuclear distribution protein nudE-like 1 1 GTENT(0.002)FPS(0.998)PK 85.67200000000001 0.011755 5386200.0 59454.0 56578.0 47757.0 62709.0 71074.0 65062.0 69543.0 62918.0 67454.0 66838.0 True False 78359.13527997665 74865.73205690767 47123.710976130555 48252.408894392036 61206.60192654229 60993.66285480534 75732.19227735791 53195.46881180645 71019.48072992961 64498.02196390385 1.214907572263691 1.1607446209560672 0.730622576340453 0.7481223055397943 0.9489686669894528 0.945667184784989 1.1741785247265604 0.8247612437103444 1.1011109886389303 1.0 15.976967295951619 -9.646157102102858 15.743137512714785 1.0000062921077426 0.9729504757323133 0.0 0.16830858352765848 0.0 0.0 0.1709747049826186 0.04146745693836204 2.2586185875692595e-10 9.646157102102858 -0.02705581637542931 GTENTFPS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 GTENTFPSPK 10 0 J3QSD2;J3QRZ1;A6NIZ0;Q9GZM8-3;Q9GZM8;Q9GZM8-2 J3QSD2 NDEL1 Nuclear distribution protein nudE-like 1 1 GTENT(0.016)FPS(0.984)PK;GTENT(0.004)FPS(0.996)PK;GTENTFPS(1)PK 109.15 0.0019259000000000001 12189000.0 129754.0 127766.0 107030.0 117767.0 111714.0 112971.0 109906.0 94147.0 103239.0 98563.0 True False 127903.68416603086 127470.16567691941 98230.40654774792 126427.97803919512 105143.20215817458 108139.49367826346 115596.39490581195 98521.4133205211 91611.13666513423 115599.4832230576 1.1064382002403195 1.1026880235351613 0.8497477999811228 1.0936725192381973 0.9095473372946931 0.9354669299827271 0.9999732843334629 0.852265170860815 0.7924874239131665 1.0 16.81877542285327 -1.5228787452837724 0.3787018229481931 0.8999508709257182 4.11972849598055 0.35631563815045253 0.08702695146993981 72.8851455160938 0.9966115770929338 0.06639814756435292 172.02199019212867 0.029999999999762727 1.5228787452837724 3.219777625054832 GTEPS(ph)PGGTPQPS(ph)RPVSPAGPPEGVPEEAQPPR ddPTM_PC-9_Lapatinib_30min_R1 1 GTEPSPGGTPQPSRPVSPAGPPEGVPEEAQPPR 33 1 I3L1Q2;Q8WUZ0;Q8WUZ0-2 I3L1Q2 BCL7C B-cell CLL/lymphoma 7 protein family member C 2 GT(0.005)EPS(0.507)PGGT(0.507)PQPS(0.644)RPVS(0.338)PAGPPEGVPEEAQPPR 72.578 1.9875999999999997e-05 14026000.0 44210.0 36834.0 40639.0 39089.0 44447.0 46112.0 41590.0 46427.0 49228.0 36677.0 True False 43579.55729287896 36748.71313607423 37297.81829107653 41963.73545708146 41832.71484616417 44139.897252322146 43743.326698567114 48584.167910096265 43683.424246178554 43016.570580969455 1.0130876707349277 0.854292023742401 0.8670569919299215 0.9755248940194742 0.9724790768111806 1.0261138127977512 1.016894794442753 1.1294291305404507 1.0155022507885394 1.0 15.392604892617193 -6.489634956102456 1.2974641898300905 1.050333521996387 0.9101167660101641 0.48884597386392836 0.05384095782388132 0.33641433374002155 1.1721402021505647 0.023001649256676263 0.0265788162113468 3.238657661864214e-07 6.489634956102456 -0.14021675598622285 GTEPS(ph)PGGTPQPSRPVS(ph)PAGPPEGVPEEAQPPR ddPTM_PC-9_AZD4547_30min_R2 4 GTEPSPGGTPQPSRPVSPAGPPEGVPEEAQPPR 33 1 I3L1Q2;Q8WUZ0;Q8WUZ0-2 I3L1Q2 BCL7C B-cell CLL/lymphoma 7 protein family member C 2 GTEPS(0.803)PGGT(0.195)PQPS(0.011)RPVS(0.991)PAGPPEGVPEEAQPPR;GT(0.011)EPS(0.765)PGGT(0.225)PQPS(0.227)RPVS(0.772)PAGPPEGVPEEAQPPR;GT(0.038)EPS(0.666)PGGT(0.25)PQPS(0.196)RPVS(0.85)PAGPPEGVPEEAQPPR;GT(0.001)EPS(0.98)PGGT(0.018)PQPS(0.005)RPVS(0.995)PAGPPEGVPEEAQPPR 113.79 6.1633e-23 71428000.0 54014.0 59733.0 87701.0 123629.0 106171.0 86701.0 67653.0 102148.0 74685.0 85577.0 True False 71189.32843900607 79040.52410751999 86538.02743718465 95128.24409900974 91430.98929486058 81279.57276404768 73673.98593877305 86363.37372752487 78632.69662755058 82580.97527761168 0.8620548279999065 0.9571275204950076 1.0479172369455625 1.1519389760077066 1.1071677100869528 0.9842408919343821 0.8921423571361795 1.045802298134624 0.9521890043464829 1.0 16.333521836327833 -10.284034373824948 14.924932489519737 0.999989818879288 1.0055317488235473 0.0 0.08617870438470826 0.0 0.0 0.09075131142785954 0.022010426040022825 5.199548411775065e-11 10.284034373824948 0.005541929944259394 GTEPS(ph)PGGTPQPSRPVS(ph)PAGPPEGVPEEAQPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GTEPSPGGTPQPSRPVSPAGPPEGVPEEAQPPR 33 1 I3L1Q2;Q8WUZ0;Q8WUZ0-2 I3L1Q2 BCL7C B-cell CLL/lymphoma 7 protein family member C 2 GT(0.003)EPS(0.487)PGGT(0.487)PQPS(0.145)RPVS(0.878)PAGPPEGVPEEAQPPR;GT(0.024)EPS(0.814)PGGT(0.158)PQPS(0.023)RPVS(0.981)PAGPPEGVPEEAQPPR;GT(0.022)EPS(0.684)PGGT(0.231)PQPS(0.122)RPVS(0.941)PAGPPEGVPEEAQPPR;GT(0.004)EPS(0.755)PGGT(0.256)PQPS(0.277)RPVS(0.708)PAGPPEGVPEEAQPPR 68.291 7.8528e-05 62482000.0 80475.1 97539.0 104716.0 124791.0 146390.0 129399.0 144126.0 115932.0 137427.0 114456.0 True False 94097.94497432381 107222.02730720588 107212.82657764136 117799.36484788042 117705.93036940784 122613.08864607936 130473.34189812098 112888.9078401078 139436.60988865895 135205.9667668023 0.6959600025390897 0.7930273335653746 0.7929592838351405 0.8712586261156353 0.8705675731931432 0.9068615208199899 0.9649969229771941 0.8349402806668581 1.0312903581330362 1.0 17.04479929495431 -2.731260813350725 0.225268050760452 1.0026488461638794 2.1364625197791957e-12 0.782024692854584 0.04581504459805005 13.347853871329786 0.2767056493885769 0.06779864893717415 4.380000633386028 0.0018566890949843367 2.731260813350725 -1.0026488461617429 GTEPS(ph)PGGTPQPSRPVS(ph)PAGPPEGVPEEAQPPR ddPTM_PC-9_Lapatinib_30min_R1 3 GTEPSPGGTPQPSRPVSPAGPPEGVPEEAQPPR 33 1 I3L1Q2;Q8WUZ0;Q8WUZ0-2 I3L1Q2 BCL7C B-cell CLL/lymphoma 7 protein family member C 2 GT(0.047)EPS(0.911)PGGT(0.043)PQPS(0.056)RPVS(0.944)PAGPPEGVPEEAQPPR;GT(0.006)EPS(0.884)PGGT(0.088)PQPS(0.068)RPVS(0.954)PAGPPEGVPEEAQPPR;GT(0.008)EPS(0.7)PGGT(0.219)PQPS(0.102)RPVS(0.971)PAGPPEGVPEEAQPPR 74.84100000000001 2.559e-07 42766000.0 88774.0 77290.0 96245.0 74182.0 106430.0 105201.0 92741.0 84990.0 106944.0 84977.0 True False 87508.06648084236 77111.03975368357 88332.10761644389 79637.5917438975 100169.99664943083 100701.79846550872 97542.67519480191 88938.94567124895 94898.84054975463 99665.161225265 0.878020618288622 0.7737010486482413 0.8862887144364726 0.7990514515287762 1.0050653148799389 1.0104011996519096 0.9787038318669269 0.892377482541041 0.9521766621664571 1.0 16.604801666407454 -6.26129180714341 24.99999977128877 0.9698828012746173 0.8336553730277783 0.7009405727570917 0.0444021277065621 7.94905529417863 1346642.520169855 0.013835613860223724 0.01672766681756594 5.479086954545174e-07 6.26129180714341 -0.1362274282468391 GTEPSPGGT(ph)PQPSRPVSPAGPPEGVPEEAQPPR ddPTM_PC-9_AZD4547_30min_R2 1 GTEPSPGGTPQPSRPVSPAGPPEGVPEEAQPPR 33 1 I3L1Q2;Q8WUZ0;Q8WUZ0-2 I3L1Q2 BCL7C B-cell CLL/lymphoma 7 protein family member C 1 GT(0.001)EPS(0.168)PGGT(0.609)PQPS(0.111)RPVS(0.111)PAGPPEGVPEEAQPPR 78.108 3.6718000000000005e-08 79913000.0 47330.0 35781.0 57957.0 60873.0 73582.0 66236.0 51629.0 57330.0 45527.0 61755.0 True False 62379.95547484269 47346.50851440869 57188.45231156895 46839.67032847479 63366.40941777354 62094.25244921589 56223.88098137419 48470.96581234089 47933.46427478741 59592.97624675909 1.046766907840673 0.7944981354574246 0.9596508836002144 0.7859931367502747 1.0633200992578327 1.041972667921462 0.9434648933888727 0.8133670923169731 0.8043475472060221 1.0 15.862854681191553 -10.633158850130274 5.192590479622157 1.0000020022555642 0.9165414999973641 0.05239040257411576 0.10582475108405923 2.501967995665096e-06 4.289012358266791e-07 0.10451407965803262 0.025347779520836014 2.3272398768856517e-11 10.633158850130274 -0.08346050225820012 GTEPSPGGTPQPS(ph)RPVSPAGPPEGVPEEAQPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTEPSPGGTPQPSRPVSPAGPPEGVPEEAQPPR 33 1 I3L1Q2;Q8WUZ0;Q8WUZ0-2 I3L1Q2 BCL7C B-cell CLL/lymphoma 7 protein family member C 1 GT(0.003)EPS(0.061)PGGT(0.204)PQPS(0.568)RPVS(0.164)PAGPPEGVPEEAQPPR 55.022 0.00058119 3877300.0 6475.8 6527.1 6787.3 8501.8 10745.0 12259.0 12430.0 13623.0 14074.0 9625.6 True False 7572.0250371198745 7175.067351898868 6949.134972978588 8025.471709207489 8639.594383627893 11616.116459263883 11252.540414593119 13265.410684761633 14279.805624607894 11370.645083792331 0.6659274809230487 0.6310167364317947 0.6111469421276595 0.70580619217875 0.7598156762401048 1.0215881661649475 0.989613195352693 1.166636596869081 1.2558483286900115 1.0 13.473026483629074 -6.797467687096619 1.1712237590490364 1.143754525853633 0.6317580212168614 0.8930543405934733 0.07274157481376346 0.13450916991911527 0.38940886532001495 0.03757638583384473 0.032734760736337104 1.594161487031132e-07 6.797467687096619 -0.5119965046367716 GTEPSPGGTPQPSRPVS(ph)PAGPPEGVPEEAQPPR ddPTM_PC-9_AZD4547_30min_R2 2 GTEPSPGGTPQPSRPVSPAGPPEGVPEEAQPPR 33 1 I3L1Q2;Q8WUZ0;Q8WUZ0-2 I3L1Q2 BCL7C B-cell CLL/lymphoma 7 protein family member C 1 GT(0.009)EPS(0.276)PGGT(0.047)PQPS(0.097)RPVS(0.571)PAGPPEGVPEEAQPPR;GT(0.005)EPS(0.244)PGGT(0.276)PQPS(0.067)RPVS(0.408)PAGPPEGVPEEAQPPR 83.939 1.166e-11 92375300.0 24116.0 20959.3 32390.0 37166.0 37244.0 33294.0 26612.0 29082.0 24017.1 30224.0 True False 31784.38635603859 27733.983843549522 31960.487436749972 28597.952908975964 32073.31347823595 31212.120916785338 28980.416445724884 24588.045137877136 25286.59487411858 29165.86695946961 1.0897802695256003 0.9509055184983903 1.0958181864150964 0.9805281272357564 1.0996866139040775 1.0701592021989028 0.993641522331483 0.8430418054106175 0.8669927387811969 1.0 14.831993338650134 -7.585830656820807 4.951838343462502 0.892614746271077 1.044135359243021 0.5333786726657379 0.060038382601269875 0.14365808486948875 6.997626680793978 0.02780352664899506 0.015749356957292262 2.595191100141714e-08 7.585830656820807 0.15152061297194397 GTEPSPGGTPQPSRPVS(ph)PAGPPEGVPEEAQPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GTEPSPGGTPQPSRPVSPAGPPEGVPEEAQPPR 33 1 I3L1Q2;Q8WUZ0;Q8WUZ0-2 I3L1Q2 BCL7C B-cell CLL/lymphoma 7 protein family member C 1 GT(0.002)EPS(0.184)PGGT(0.049)PQPS(0.04)RPVS(0.724)PAGPPEGVPEEAQPPR;GTEPS(0.013)PGGT(0.015)PQPS(0.032)RPVS(0.94)PAGPPEGVPEEAQPPR;GT(0.002)EPS(0.036)PGGT(0.211)PQPS(0.164)RPVS(0.587)PAGPPEGVPEEAQPPR 74.581 3.8584e-08 123682600.0 25778.8 37057.3 37737.0 49570.0 69358.0 63084.0 79311.0 77244.0 63160.3 54456.0 True False 30142.641685491486 40736.103840836215 38636.79319836945 46792.75360810833 55767.79779056892 59775.76398696491 71798.08791808481 75216.42684678332 64083.899899951815 64328.44172654123 0.46857409998562044 0.6332518361629913 0.6006175831619488 0.7274038100755383 0.8669228772497954 0.929227607301143 1.1161173190436804 1.1692561614740595 0.9961985426659493 1.0 15.973169121232292 -6.328589696711904 0.9394358213835812 1.087713136351821 0.5357447488100749 0.912833014295074 0.0655448332352362 0.15028477935413284 0.2844173506102303 0.03255268422017615 0.048083973892098994 4.6925650673846443e-07 6.328589696711904 -0.5519683875417462 GTEPSPGGTPQPSRPVS(ph)PAGPPEGVPEEAQPPR ddPTM_PC-9_Lapatinib_30min_R1 2 GTEPSPGGTPQPSRPVSPAGPPEGVPEEAQPPR 33 1 I3L1Q2;Q8WUZ0;Q8WUZ0-2 I3L1Q2 BCL7C B-cell CLL/lymphoma 7 protein family member C 1 GTEPS(0.007)PGGT(0.028)PQPS(0.019)RPVS(0.946)PAGPPEGVPEEAQPPR;GT(0.003)EPS(0.057)PGGT(0.054)PQPS(0.034)RPVS(0.853)PAGPPEGVPEEAQPPR 75.536 3.4648e-08 131542000.0 18780.2 18242.4 21527.1 21351.4 28358.0 27272.0 16477.3 26608.0 26204.8 24507.2 True False 18512.39090413312 18200.160843609712 19757.224935009053 22921.653182182432 26690.03819397311 26105.64013413709 17330.413969951896 27844.30481727964 23253.339475222634 28743.236866208645 0.644060757328859 0.6331980259678524 0.6873695202448198 0.7974624879193676 0.9285675902894105 0.9082359184406128 0.6029388426439201 0.9687254412885623 0.8090021170357439 1.0 14.810934916914508 -3.2399985655260566 0.23277790312910573 0.9385280306752932 4.7310266849032534e-27 0.4478480415460878 0.10519543546471087 23.3161329796916 0.6093872830459827 0.16399936750994004 7.1047349098256785 0.0005754418380174412 3.2399985655260566 -0.9385280306752932 GTFHDDRDDGVDYWAK ddPTM_PC-9_AZD4547_30min_R2 2 GTFHDDRDDGVDYWAK 16 1 E9PK91;Q9NYF8-3;H0YF63 E9PK91 BCLAF1 Bcl-2-associated transcription factor 1 0 ; 67.095 0.011523 9149100.0 71483.0 85787.0 105530.0 141685.0 107741.0 110966.0 87120.0 114154.0 91048.0 105549.0 False True 94213.10706123358 113515.97009378113 104130.60324792285 109021.71226142882 92783.02189503332 104027.27847816453 94873.51122619714 96514.1222979585 95860.611401824 101853.76163661505 0.9249840707637178 1.1144995360973853 1.022354025759313 1.0703749229251538 0.9109434978558424 1.021339583404921 0.9314679173527097 0.9475754331223736 0.9411592646310611 1.0 16.636139736962278 -6.255002624752658 24.97712897980382 0.9578920008788998 1.038106516838054 0.3118228788799631 0.05386043578413397 568.5826045371324 2206322.544092503 0.015102812363953 0.019025863220382806 5.559008975529116e-07 6.255002624752658 0.0802145159591543 GTFS(ph)DQELDAQSLDDEDDNMHHAVYPAVNR ddPTM_PC-9_AZD4547_30min_R2 2 GTFSDQELDAQSLDDEDDNMHHAVYPAVNR 30 0 Q9P270;D6RIF6 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 GT(0.273)FS(0.727)DQELDAQSLDDEDDNMHHAVYPAVNR;GT(0.269)FS(0.729)DQELDAQS(0.002)LDDEDDNMHHAVYPAVNR 73.892 1.9355e-06 6974700.0 11500.7 15657.5 18115.3 18142.8 15805.8 16586.9 16560.3 21325.0 15821.4 14691.4 True False 15157.683370579423 20718.480675899333 17875.079285673255 13960.257763465794 13611.437497967498 15549.718520893472 18034.134618448 18029.711249750017 16657.686903971728 14177.058557714132 1.069169835821247 1.4614089792713616 1.2608454153521802 0.9847076321674378 0.9601030737480545 1.0968226206861815 1.2720646208119897 1.2717526118942035 1.1749748254307533 1.0 13.791270614214476 -11.981583110547529 1.6480786541183334 9.869262548048836e-05 1.1753899935280019 0.11372942500691197 0.1441891961816162 1813636.2090727065 142640.77467455863 6731519.142967818 0.04174448462195359 1.0433184547012913e-12 11.981583110547529 1.1752913009025214 GTGASGS(ph)FK ddPTM_PC-9_Lapatinib_30min_R1 1 GTGASGSFK 9 0 P10412;P22492;Q02539;P16401;P16402;P16403 P10412;P16401;P16402;P16403 HIST1H1E;HIST1H1T;HIST1H1A;HIST1H1B;HIST1H1D;HIST1H1C Histone H1.4;Histone H1t;Histone H1.1;Histone H1.5;Histone H1.3;Histone H1.2 1 GTGAS(0.414)GS(0.585)FK 71.221 0.035562 3178900.0 32894.0 34672.0 34011.0 25933.0 24124.0 23472.0 25297.0 29453.0 28861.0 22196.0 True False 32424.925527979176 34591.719114241336 31214.746866256653 27840.199329951975 22705.07374960885 22468.157275904414 26606.75488082837 30821.49390346277 25610.370260196643 26032.549025689066 1.2455532301497667 1.3287872455404206 1.1990660935836044 1.0694380831657748 0.8721801974598552 0.8630794185284242 1.0220572274567763 1.183959890867696 0.9837826574310562 1.0 14.668028962389124 -5.738848955702469 2.6762048405023555 0.9913795385544112 1.2828521078708472 0.6663680917817346 0.08636258685759794 0.17722219300234496 2.5857442429708684 0.028369274366968882 0.05192293449755764 1.8245301496097905e-06 5.738848955702469 0.29147256931643606 GTGIVSAPVPK ddPTM_PC-9_Lapatinib_30min_R1 1 GTGIVSAPVPK 11 0 H0YEN5;P15880;E9PQD7;E9PMM9;I3L404;E9PM36 H0YEN5 RPS2 40S ribosomal protein S2 0 119.22 0.004543600000000001 8959700.0 93744.0 91558.0 88688.0 89348.0 87931.0 93315.0 93206.0 73595.0 74919.0 85469.0 False True 92407.19336945601 91346.00307630685 81396.41498558034 95918.94997619039 82759.07145899736 89324.13497788942 98031.75061953951 77014.49237175641 66480.83328795509 100242.20276971615 0.921839213586923 0.9112529508769244 0.8119974694946622 0.9568719294461489 0.8255911100548904 0.891083121777476 0.9779488869049031 0.7682841183037431 0.6632020391718626 1.0 16.61313049702276 -7.784781370310699 24.996955970980512 0.7868072382459997 0.8956365774363991 0.1495612704186714 0.09189704157334289 353.9247915262199 379012.79494392226 0.04731133422473437 0.022748784052233895 1.6414158760976135e-08 7.784781370310699 0.10882933919039939 GTGQS(ph)DDSDIWDDTALIK ddPTM_PC-9_AZD4547_30min_R2 2 GTGQSDDSDIWDDTALIK 18 0 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 1 GT(0.067)GQS(0.652)DDS(0.278)DIWDDT(0.003)ALIK;GT(0.14)GQS(0.715)DDS(0.104)DIWDDT(0.041)ALIK 136.58 4.4406999999999995e-08 0.0 4061.4799999999996 5152.1 5351.2 4825.74 6304.9 7092.7 4596.12 4494.0 3546.27 5388.2 True False 5352.946155967977 6817.415570193263 5280.239591588033 3713.240199939775 5429.573465495913 6649.1923477648625 5005.165776135767 3799.5555618465023 3733.7185923463076 5199.560758040438 1.0294996837358519 1.311152208318948 1.0155164709678286 0.7141449773805868 1.0442369496499855 1.278798855746182 0.9626131915846807 0.7307454876781637 0.7180834624487468 1.0 12.344174038884628 -7.578245156618036 5.603593123554885 0.798198676098108 1.0624819848995743 0.3013296080158694 0.16902000583259563 0.25030161874220497 16.55877417748891 0.0864105237448914 0.04936227111047285 2.6409175544283508e-08 7.578245156618036 0.26428330880146633 GTGQS(ph)DDSDIWDDTALIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTGQSDDSDIWDDTALIK 18 0 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 1 GT(0.004)GQS(0.809)DDS(0.18)DIWDDT(0.007)ALIK 135.26 5.6905e-07 0.0 4154.5 4235.4 2880.8 4678.7 4874.0 3867.9 5401.1 5519.4 5587.0 3476.1 True False 4857.774794884728 4655.862521216538 2949.489197494839 4416.567607550057 3918.9746883017565 3665.0605149512016 4889.468707422276 5374.521598287698 5668.699305434441 4106.289413207543 1.1830083820346649 1.133836915206546 0.7182857564807901 1.075561696490396 0.954383457653203 0.8925480272196197 1.1907267645811086 1.3088511445396398 1.3804919076579296 1.0 12.00361959751652 -7.417850950777068 5.030103915425675 1.2572179675623576 0.9897414401230663 0.3425435019082178 0.15308943519685786 0.23683082940570147 9.125995226437 0.06659240527678081 0.04374468663910739 3.820753760443493e-08 7.417850950777068 -0.2674765274392913 GTGQSDDS(ph)DIWDDTALIK ddPTM_PC-9_Lapatinib_30min_R1 1 GTGQSDDSDIWDDTALIK 18 0 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 1 GTGQS(0.014)DDS(0.842)DIWDDT(0.145)ALIK 218.22 1.1547e-27 2968300.0 14574.0 16627.0 16993.0 16688.0 16109.0 16315.0 16181.0 14619.0 16946.0 13977.0 True False 14366.172087455718 16588.501203059845 15595.90113487692 17915.291189536063 15161.500291512542 15617.245482122555 17018.77300575894 15298.252109283345 15037.36303070898 16392.905826818176 0.8763651935310457 1.0119317086493405 0.9513811217876097 1.0928685480659153 0.9248818026337282 0.9526831696045817 1.0381791480749476 0.9332239366772901 0.9173091817625415 1.0 14.000783990567607 -10.022547952866704 14.862718584598573 0.9999945465892804 0.970635907878071 0.022552242132400036 0.06093036964528236 0.0 0.0 0.0573063719182988 0.013898836731769162 9.494061642050697e-11 10.022547952866704 -0.029358638711209473 GTGQSDDSDIWDDT(ph)ALIK ddPTM_PC-9_AZD4547_30min_R2 3 GTGQSDDSDIWDDTALIK 18 0 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 1 GT(0.004)GQS(0.003)DDS(0.046)DIWDDT(0.947)ALIK;GTGQS(0.003)DDS(0.006)DIWDDT(0.99)ALIK;GT(0.023)GQS(0.016)DDS(0.189)DIWDDT(0.772)ALIK 122.33 0.00014406 5961100.0 7276.73 10030.23 9874.3 15164.35 11887.18 12440.56 10308.2 10795.11 10782.310000000001 9753.73 True False 9590.578774613397 13272.30569566187 9743.360330246998 11668.443394372005 10236.850244662674 11662.649816559237 11225.609830370566 9126.973796449663 11352.240894077864 9412.254881504357 1.0189459269169874 1.4101090400497698 1.0351781218115208 1.2397075452452093 1.0876086945731458 1.2390920096604099 1.1926589294165375 0.9696904632687658 1.2061127792433346 1.0 13.200324673573583 -8.760512655792951 0.4013805570935121 0.9894817473448171 1.189281819885437 0.12482452067429428 0.12441041279505818 3.3047058738007355 1.226896195033365 0.21357700399457544 0.09100463174039375 1.7357506805541033e-09 8.760512655792951 0.19980007254061982 GTGQSDDSDIWDDT(ph)ALIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTGQSDDSDIWDDTALIK 18 0 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 1 GTGQSDDS(0.012)DIWDDT(0.988)ALIK 155.48 3.8596999999999997e-05 2120300.0 5899.6 6891.5 5374.5 5880.2 5075.6 6392.3 5969.2 6074.7 6369.8 5211.4 True False 6898.285757588619 7575.642575663172 5502.648462904752 5550.751457865616 4081.072615499466 6057.07653499898 5403.754162734451 5915.245561676685 6462.946274522338 6156.1855665803005 1.1205454551332747 1.2305741101744216 0.8938405776422068 0.9016543438844069 0.6629222870821389 0.9839009025135065 0.8777763607499867 0.9608621276441711 1.0498296720630598 1.0 12.58782100429933 -5.267000175090314 24.838310137518352 0.9064098076568207 1.175559789929524 0.5049127538755076 0.10229277386070079 293.7411513904806 1312055.3867995224 0.02732445169970552 0.05961727166555922 5.4075410493492415e-06 5.267000175090314 0.26914998227270337 GTGQSDDSDIWDDT(ph)ALIK ddPTM_PC-9_Lapatinib_30min_R1 1 GTGQSDDSDIWDDTALIK 18 0 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 1 GTGQS(0.002)DDS(0.001)DIWDDT(0.997)ALIK 148.18 9.833799999999999e-05 4205900.0 12693.0 16215.0 16315.0 16189.0 17890.0 17386.0 15592.0 19830.0 17507.0 15567.0 True False 12511.995492388878 16177.455163746637 14973.643677721237 17379.593064920857 16837.745373093265 16642.441308745503 16399.277467758064 20751.37419297412 15535.177303117096 18257.73520827635 0.6852983324414251 0.8860603453386316 0.8201260182004166 0.9519030080490254 0.9222253023726955 0.9115282437222212 0.8982098426054599 1.1365798636167856 0.850881948165997 1.0 14.156220195997898 -3.47721186480343 0.45504474568610853 0.9751497176150516 1.3899524902181733e-11 0.5018845531782266 0.07858617175393268 12.768831356195971 0.8121431705350926 0.04857378335594838 8.6400779823545 0.00033326379477837233 3.47721186480343 -0.9751497176011521 GTHDLWDSR ddPTM_PC-9_AZD4547_30min_R2 1 GTHDLWDSR 9 0 E9PGM4;Q04446 E9PGM4 GBE1 1,4-alpha-glucan-branching enzyme 0 76.22800000000001 0.019798 0.0 5444.3 3793.5 6518.2 7232.3 5990.2 6463.3 4486.8 7905.3 8841.0 7769.2 False True 7175.474151525173 5019.67468906429 6431.764409083775 5565.004972921136 5158.564128378504 6059.148829262289 4886.116507916671 6683.717530722105 9308.317210740779 7497.202672760435 0.9570868582219075 0.6695396814204129 0.8578885605496949 0.742277515471264 0.6880651829143022 0.8081879460557971 0.6517252795725244 0.8914948444712635 1.2415720392034566 1.0 12.872136687879514 -8.05235482626809 5.199720207932818 1.1127617185091636 0.7648976710992669 0.6487148055035861 0.10274780545739672 0.11693035059480969 6.921073892391518 0.06527952109576345 0.024521700711231487 8.864314859108232e-09 8.05235482626809 -0.34786404740989674 GTHDLWDSR ddPTM_PC-9_Lapatinib_30min_R1 1 GTHDLWDSR 9 0 E9PGM4;Q04446 E9PGM4 GBE1 1,4-alpha-glucan-branching enzyme 0 73.885 0.024883000000000002 0.0 1302.5 3251.8 2963.5 3524.9 3963.4 3009.6 2642.1 3177.1 3199.6 2642.8 False True 1283.926111150754 3244.2706568899957 2719.8524694408156 3784.1329047216964 3730.2806043442088 2880.886423720259 2778.895010105413 3324.7196645737795 2839.227354718309 3099.604458690352 0.41422256557639603 1.046672470674135 0.8774837259687032 1.220843806090204 1.2034698794827294 0.9294367917309984 0.8965321372906897 1.0726270751263995 0.9159966674967108 1.0 11.597868409227905 -4.760001248093 24.999475553679172 1.0215494418091648 0.41422182550228875 0.712297410129231 0.11512088204614136 20.669035425688413 359170.6004821679 0.030005564227146005 0.1830698531517171 1.7377958345944323e-05 4.760001248093 -0.6073276163068762 GTHDRDPSEKPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GTHDRDPSEKPPR 13 2 Q969S3 Q969S3 ZNF622 Zinc finger protein 622 0 ; 40.725 0.040844 1101460.0 995.48 710.69 1769.43 1901.0 1894.7199999999998 1663.6699999999998 2138.81 692.31 1684.86 1897.9499999999998 False True 1163.9951023737754 781.2426064134158 1811.6199218006425 1794.4931331251553 1523.4632173613256 1576.424216476347 1936.2064331565482 674.1375960630791 1709.49789005804 2242.0333108360674 0.5191694060690448 0.34845272041122616 0.8080254263149547 0.800386472605966 0.679500705898619 0.703122566849147 0.8635939634788591 0.30068134706334454 0.762476579538668 1.0 11.130591997694363 -12.414258074611745 1.37210219387316 6.968452942196286 0.6429378005708476 0.25292210619458855 0.18416231462737032 764386.0518951253 19125.28823188018 14179589.644022318 0.05329241422087849 3.8524935953338457e-13 12.414258074611745 -6.325515141625439 GTHEMAGAS(ph)GDKELGLGCSPPAETLADAK ddPTM_PC-9_Lapatinib_30min_R1 1 GTHEMAGASGDKELGLGCSPPAETLADAK 29 1 O60303 O60303 KIAA0556 Uncharacterized protein KIAA0556 1 GT(0.233)HEMAGAS(0.636)GDKELGLGCS(0.109)PPAET(0.022)LADAK 46.63 0.011116 4808700.0 10264.0 12976.0 22516.0 16722.0 21956.0 20310.0 18370.0 16790.0 23038.0 17360.0 True False 10117.63347781292 12945.954869243065 20664.821394273455 17951.791662956737 20664.591247156848 19441.388644922423 19321.10871489968 17570.124694908503 20443.217839105022 20360.65286925403 0.4969208768885419 0.6358320114966616 1.01493903594215 0.8816903749714805 1.0149277324187274 0.9548509455843747 0.9489434763693588 0.8629450542541584 1.0040551238892574 1.0 14.313496202069835 -5.125411685345283 3.615813622174322 0.9539420289478143 0.5194325111712441 0.9000185836009718 0.05321141630955111 0.06311129996984914 1.4494193314845614 0.013384893564968565 0.04410195489198372 7.491836910291852e-06 5.125411685345283 -0.4345095177765702 GTHEMAGASGDKELGLGCS(ph)PPAETLADAK ddPTM_PC-9_AZD4547_30min_R2 2 GTHEMAGASGDKELGLGCSPPAETLADAK 29 1 O60303 O60303 KIAA0556 Uncharacterized protein KIAA0556 1 GT(0.002)HEMAGAS(0.041)GDKELGLGCS(0.898)PPAET(0.06)LADAK;GT(0.008)HEMAGAS(0.232)GDKELGLGCS(0.734)PPAET(0.026)LADAK 69.248 5.719e-05 15817500.0 48231.0 54387.0 77655.0 88623.0 85458.0 89697.0 72167.0 83060.0 73425.0 86643.0 True False 63567.45473287852 71966.53415424781 76625.24396112439 68192.33656170094 73593.6318124553 84088.23241043136 78589.72319399622 70224.9855289208 77306.0955998915 83609.65494207674 0.7602884472722308 0.8607443028452267 0.9164640616470547 0.8156036119147168 0.8802049459890684 1.0057239498080235 0.9399599035355637 0.8399147870849534 0.9246072795474132 1.0 16.351381928707042 -6.530365721922462 24.93542739045578 0.9331345305799258 0.8457698812404522 0.4238085357274666 0.05655830168263898 206.96459173679318 689291.0436230444 0.019259002527845997 0.019294352134293223 2.948725042241273e-07 6.530365721922462 -0.08736464933947363 GTHEMAGASGDKELGLGCS(ph)PPAETLADAK ddPTM_PC-9_Lapatinib_30min_R1 1 GTHEMAGASGDKELGLGCSPPAETLADAK 29 1 O60303 O60303 KIAA0556 Uncharacterized protein KIAA0556 1 GT(0.078)HEMAGAS(0.072)GDKELGLGCS(0.627)PPAET(0.223)LADAK 44.596000000000004 0.013766999999999998 5997000.0 26980.0 30741.0 38371.0 36444.0 43312.0 43214.0 35554.0 39591.0 47737.0 30802.0 True False 26595.260252473963 30669.821103221406 35216.284496343345 39124.21333362008 40764.47331466829 41365.83795675415 37394.812152941944 41430.54239405135 42360.35636710463 36126.08465891491 0.736178871958409 0.848966097289288 0.9748159765675839 1.0829906894979642 1.1283944468255227 1.1450407191177916 1.0351194297972157 1.1468317916325164 1.1725698139460923 1.0 15.140753283662306 -5.250053644173207 1.305879247263742 1.1124741054411151 0.7073675980899852 0.8591643970406924 0.0507241038779797 0.22369269398057967 0.5707378505825718 0.015524621994518201 0.09649653418665034 5.6227186892574894e-06 5.250053644173207 -0.40510650735112996 GTHTAVSSNDR ddPTM_PC-9_Lapatinib_30min_R1 1 GTHTAVSSNDR 11 0 Q9NZ08;Q9NZ08-2 Q9NZ08 ERAP1 Endoplasmic reticulum aminopeptidase 1 0 89.266 0.010178 0.0 791.52 0.0 837.47 0.0 434.64 0.0 0.0 1114.4 555.9 0.0 False True 780.2327796530093 0.0 768.6164493276868 0.0 409.07532973511775 0.0 0.0 1166.1790923172136 493.2886881134859 0.0 0.0 GTITDAPGFDPLRDAEVLR ddPTM_PC-9_Lapatinib_30min_R1 1 GTITDAPGFDPLRDAEVLR 19 1 P50995;P50995-2 P50995 ANXA11 Annexin A11 0 83.37 0.0020221 2794200.0 10806.0 8813.6 10650.0 11465.0 15281.0 10899.0 12104.0 10993.0 10675.0 8911.8 False True 10651.904458422303 8793.192650705967 9774.398110188855 12308.17434611883 14382.201623601919 10432.875176809916 12730.685894673152 11503.774911919538 9472.669087266526 10452.19275577293 1.0191071584035865 0.8412773143558161 0.9351528754375757 1.1775686340381362 1.3759985066921365 0.9981518156606569 1.2179918790381825 1.1006087603546921 0.9062853420909793 1.0 13.351518015255104 -5.748523683468989 21.929325448257075 1.1259402111136647 0.9227883851369623 0.2772827842498814 0.13069933373187645 62.32712633126512 105818.9518005609 0.03590056518409364 0.06147680596964112 1.7843346804024178e-06 5.748523683468989 -0.20315182597670245 GTLDPVEK ddPTM_PC-9_Lapatinib_30min_R1 2 GTLDPVEK 8 0 P11142;E9PKE3;P11142-2;E9PN89;E9PNE6;A8K7Q2 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 ; 117.04 0.016422 51595000.0 430880.0 397030.0 389860.0 421050.0 434820.0 389080.0 427900.0 358480.0 389040.0 389520.0 False True 424735.57218628493 396110.7014284511 357807.2157031194 452015.4215816243 409244.7424890117 372439.95538977924 450054.56826921966 375136.28949558106 345222.218427182 456848.012997225 0.929708699835945 0.8670513828651745 0.7832084315211695 0.9894218836941072 0.8958006401387097 0.8152382078808375 0.9851297487682263 0.8211402453836649 0.7556609826587535 1.0 18.801354754894483 GTLS(ph)DSEIETNSATSTIFGK ddPTM_PC-9_AZD4547_30min_R2 2 GTLSDSEIETNSATSTIFGK 20 0 Q8WXG6-4;Q8WXG6-7;Q8WXG6-2;Q8WXG6;A0A0A0MRB5;Q8WXG6-6;Q8WXG6-8;Q8WXG6-5;Q8WXG6-3;F8W8U2 Q8WXG6-4 MADD MAP kinase-activating death domain protein 1 GT(0.001)LS(0.721)DS(0.278)EIETNSATSTIFGK;GT(0.109)LS(0.874)DS(0.017)EIETNSATSTIFGK 306.4 7.813299999999997e-139 7206000.0 20410.4 20810.9 27076.4 39680.2 31205.7 27548.7 26374.3 31804.8 28992.8 29816.1 True False 26900.48263730679 27537.61644566972 26717.349244594538 30532.542942978747 26873.327204591 25826.07543401947 28721.561606210813 26890.098961596705 30525.300218025677 28772.247414314534 0.934945478882664 0.9570895192556084 0.9285805470761502 1.0611803278109044 0.9340016724317893 0.8976036894904043 0.9982383785536856 0.9345845868202344 1.0609286017344262 1.0 14.81239029464309 -8.257683428426354 24.929437060888894 1.0304643021749829 0.9571788906563454 0.3053531897266083 0.04501934974928713 362.0828858809663 2403301.150280942 0.032777102954974865 0.011346163854348138 5.52480013444233e-09 8.257683428426354 -0.07328541151863743 GTLS(ph)DSEIETNSATSTIFGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GTLSDSEIETNSATSTIFGK 20 0 Q8WXG6-4;Q8WXG6-7;Q8WXG6-2;Q8WXG6;A0A0A0MRB5;Q8WXG6-6;Q8WXG6-8;Q8WXG6-5;Q8WXG6-3;F8W8U2 Q8WXG6-4 MADD MAP kinase-activating death domain protein 1 GT(0.075)LS(0.742)DS(0.184)EIETNSATSTIFGK;GT(0.039)LS(0.79)DS(0.154)EIET(0.01)NS(0.007)ATSTIFGK;GT(0.033)LS(0.964)DS(0.003)EIETNSATSTIFGK 176.46 5.334399999999999e-37 0.0 15656.099999999999 15634.800000000001 19081.5 22597.4 22948.4 21909.1 17952.399999999998 15947.999999999998 16549.8 16133.199999999999 True False 18306.368507929907 17186.91961720648 19536.475326991735 21331.340939759277 18451.82575646779 20760.148227233727 16251.818707879434 15529.381898302749 16791.80951585446 19058.021449659074 0.9605597599040054 0.9018207720358051 1.0251051179996031 1.1192841290532218 0.9681920972335706 1.0893128797273497 0.8527547705205338 0.8148475401459132 0.8810888139783706 1.0 14.21811073001818 -7.278084592143396 24.795914129797946 0.8717433963059862 1.0094193822326591 0.39557007071239036 0.07382309619066306 732.6176891470071 1091355.4972313645 0.03161539703710287 0.02137839460618307 5.271271772704301e-08 7.278084592143396 0.13767598592667296 GTLSDS(ph)EIETNSATSTIFGK ddPTM_PC-9_Lapatinib_30min_R1 1 GTLSDSEIETNSATSTIFGK 20 0 Q8WXG6-4;Q8WXG6-7;Q8WXG6-2;Q8WXG6;A0A0A0MRB5;Q8WXG6-6;Q8WXG6-8;Q8WXG6-5;Q8WXG6-3;F8W8U2 Q8WXG6-4 MADD MAP kinase-activating death domain protein 1 GT(0.001)LS(0.371)DS(0.628)EIETNSATSTIFGK 159.8 9.389600000000001e-21 0.0 7321.2 5565.7 8243.9 5042.0 7558.3 8088.4 4499.5 3704.6 7285.6 4833.7 True False 7216.798345456352 5552.81296360559 7566.118364374267 5412.805499618936 7113.735654189537 7742.477986981309 4732.462093777415 3876.729240307208 6465.01900723082 5669.1986044996065 1.272983864020644 0.9794705303141714 1.3346010419125354 0.9547743653437766 1.254804453056806 1.3657094286370837 0.8347673849389031 0.6838231486951741 1.1403761727626855 1.0 12.468929095486 -7.2780102728534315 24.85423325745138 0.8883935816254435 1.1823037060090318 0.39225439846095433 0.16849284080064786 762.314357573586 1143369.9663699616 0.06838577474112856 0.04625666856966157 5.272173904123446e-08 7.2780102728534315 0.2939101243835883 GTLTLCPYHSDR ddPTM_PC-9_AZD4547_30min_R2 3 GTLTLCPYHSDR 12 0 Q13200;Q13200-3;Q13200-2 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 0 ;; 87.719 0.0070715000000000005 11668000.0 94825.0 86201.0 118409.0 142318.0 137503.0 116336.0 98995.0 123886.0 97953.0 108408.0 False True 124977.37751747205 114063.78749756984 116838.81929293377 109508.78389118119 118413.08192454804 109061.49152925887 107805.36322127371 104742.26531707082 103130.59560498716 104612.66891682697 1.1946677090977975 1.0903439198961367 1.1168706477207582 1.0468023139553673 1.1319191370472843 1.0425266142093075 1.0305191936837508 1.001238821278395 0.9858327549886129 1.0 16.674698051420435 -4.8845997187107555 0.2663457696125509 0.9756245693599354 1.3025932931870252 0.7417458283495213 0.03261881799075206 4.527806407029859 0.2828358092180637 0.0443214253186254 0.4865199987903575 1.3043684371510119e-05 4.8845997187107555 0.32696872382708986 GTLTLCPYHSDR ddPTM_PC-9_Lapatinib_30min_R1 1 GTLTLCPYHSDR 12 0 Q13200;Q13200-3;Q13200-2 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 0 89.663 0.0061848 2692700.0 24776.0 19200.0 24546.0 23226.0 26750.0 22729.0 18739.0 18256.0 23171.0 17159.0 False True 24422.68969663805 19155.54357964449 22527.922630300072 24934.117519664705 25176.617592523467 21756.93365388683 19709.21372936882 19104.240406804605 20561.23797855294 20124.9102870697 1.2135552083593477 0.9518324954696554 1.1194048723175831 1.2389678842784673 1.251017631054957 1.0810946902886673 0.9793441783455819 0.9492832581260808 1.0216809757290488 1.0 14.296694731537542 -7.094068417824113 4.033142113321331 0.9845442353951595 1.147926381538853 0.4822251444735498 0.08120305360789488 0.2317796743576478 6.737833641446679 0.03487806815375307 0.0269679997528507 8.052515735949094e-08 7.094068417824113 0.1633821461436935 GTMMET(ph)LS(ph)RY(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTMMETLSRYK 11 1 P21217;K7ENC0;Q11128 P21217 FUT3;FUT5 Galactoside 3(4)-L-fucosyltransferase;Alpha-(1,3)-fucosyltransferase 5 3 GT(0.001)MMET(1)LS(1)RY(1)K 50.108000000000004 0.043902 1169700.0 8765.4 11055.0 8606.2 9235.5 12175.0 10278.0 13439.0 10774.0 10531.0 8835.8 True False 10249.209095458553 12152.467340050252 8811.404447195253 8718.064876894987 9789.396148968786 9739.00358661508 12165.960630065723 10491.19391599661 10684.995952305359 10437.660595845682 0.9819450442312585 1.164290333878751 0.8441934249809101 0.8352508492530294 0.9378917870605111 0.933063831419401 1.1655830842888228 1.0051288619379168 1.0236964360153769 1.0 13.349510774889215 GTNESLER ddPTM_PC-9_Lapatinib_30min_R1 2 GTNESLER 8 0 P08670;B0YJC4;B0YJC5;A0A1X7SBR3;A0A1W2PR46;P14136-2;P14136;P14136-3;A0A1W2PRT3 P08670 VIM;GFAP Vimentin;Glial fibrillary acidic protein 0 ; 99.01299999999999 0.024557 172084000.0 326690.0 402430.0 368400.0 491180.0 403790.0 355130.0 392350.0 348490.0 382020.0 375670.0 False True 322031.3406923916 401498.19806022634 338111.57406512386 527303.015728448 380039.86608168454 339941.9177484633 412663.9632167063 364682.1176252931 338992.8847510595 440604.0589511904 0.730886005587311 0.9112448918785467 0.7673818867442151 1.1967729416375215 0.8625428167555418 0.7715360556542709 0.9365868398920509 0.8276866956091572 0.7693821195337939 1.0 18.749123259992587 -7.798098897381328 24.987911698104373 0.8489008286579937 0.8861667729842322 0.0 0.13460006859524234 1165.1763119272484 794193.9671300155 0.07331003627506806 0.03521874531359894 1.5918461911392786e-08 7.798098897381328 0.03726594432623853 GTNT(ph)SSPYDAGADYLR ddPTM_PC-9_AZD4547_30min_R2 1 GTNTSSPYDAGADYLR 16 0 Q8ND82;Q9UJJ2 Q8ND82 ZNF280C Zinc finger protein 280C 1 GTNT(0.468)S(0.065)S(0.468)PYDAGADYLR 144.15 7.1597e-05 9093000.0 25084.0 23229.0 30615.0 43388.0 33721.0 34845.0 26258.0 28194.0 26748.0 30593.0 True False 33060.190220387805 30737.31998214692 30209.02509651437 33385.56693791773 29039.42121682941 32666.136641598634 28594.911131513767 23837.265133667173 28161.844672875737 29521.948381784467 1.1198512304420427 1.0411684074724674 1.0232734203665854 1.1308727495275066 0.9836553076133422 1.1065034129574653 0.9685983716832627 0.8074421384861971 0.9539290668989877 1.0 14.849500318697723 -7.4801561356342035 5.703932191964018 0.9059427666479031 1.0621651590358938 0.5331071917647854 0.06251137967681161 0.1352224175604237 11.349209073233707 0.02568171484057054 0.016587975223169696 3.3101209608116164e-08 7.4801561356342035 0.15622239238799074 GTNTS(ph)SPYDAGADYLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTNTSSPYDAGADYLR 16 0 Q8ND82;Q9UJJ2 Q8ND82 ZNF280C Zinc finger protein 280C 1 GTNT(0.018)S(0.804)S(0.179)PYDAGADYLR 147.49 3.0126999999999998e-05 5704400.0 24453.0 27380.0 25428.0 26526.0 31496.0 23611.0 25176.0 20790.0 23724.0 22382.0 True False 28592.409931235114 30098.10545188385 26034.299956227012 25039.834218452317 25324.584895927783 22372.797595210024 22791.147021544355 20244.28452882582 24070.918618601492 26439.67942418547 1.0814204466140558 1.1383687740310446 0.9846677616072894 0.9470551369676344 0.957824960342081 0.8461826346784183 0.8620054220739284 0.7656781386807412 0.9104088681416774 1.0 14.690417064112843 -5.684971403841868 0.9490163846766734 0.864955972921091 1.1335928553344479 0.6365166003015575 0.06340013875157226 0.42220159262001455 0.6795683040541796 0.024786104743700747 0.08763399718747002 2.0655161554248707e-06 5.684971403841868 0.2686368824133568 GTNTSS(ph)PYDAGADYLR ddPTM_PC-9_AZD4547_30min_R2 1 GTNTSSPYDAGADYLR 16 0 Q8ND82;Q9UJJ2 Q8ND82 ZNF280C Zinc finger protein 280C 1 GTNT(0.001)S(0.121)S(0.878)PYDAGADYLR 161.2 5.8226e-05 8406300.0 30642.0 24510.0 32541.0 49067.0 42091.0 35195.0 35544.0 39001.0 31129.0 32669.0 True False 40385.51860680604 32432.378180826625 32109.485078088324 37755.36122759307 36247.391193546064 32994.25108626961 38707.34714214811 32974.29160382184 32774.41538888696 31525.268253669703 1.2810523381384697 1.0287740589503573 1.018531700340111 1.1976222033637463 1.1497885093912463 1.0465969970748434 1.2278197549561651 1.0459638705844625 1.0396236798103011 1.0 14.944221026283513 -7.97418728868916 24.931149069795527 1.0274724093754066 1.1273448055880766 0.26033026246843716 0.08254873269058302 304.79011620331977 294380.79913919675 0.04457639739522788 0.02141266986622568 1.0612378016706635e-08 7.97418728868916 0.09987239621266997 GTNTSS(ph)PYDAGADYLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTNTSSPYDAGADYLR 16 0 Q8ND82;Q9UJJ2 Q8ND82 ZNF280C Zinc finger protein 280C 1 GTNTS(0.045)S(0.955)PYDAGADYLR 133.9 3.5804e-06 6152100.0 26789.0 24522.0 28420.0 27230.0 22549.0 23985.0 25113.0 21141.0 21084.0 20151.0 True False 31323.848593132014 26956.382099747836 29097.640583450186 25704.391380851113 18130.6853193509 22727.184376820638 22734.114837624842 20586.071150741067 21392.31361299081 23804.216784771776 1.3158949473679284 1.1324204590924658 1.2223733654645912 1.079825125659876 0.7616585533261321 0.9547545538805484 0.9550456981289337 0.8648077496887254 0.8986774824986501 1.0 14.538929541133708 -6.0111729962656675 4.370561307187149 0.9037537986916598 1.209607552167448 0.7899790853768054 0.07377106932964327 0.08727967040910876 4.111124717997039 0.021113595249414897 0.029874534937423335 9.74601339030493e-07 6.0111729962656675 0.30585375347578825 GTNTSS(ph)PYDAGADYLR ddPTM_PC-9_Lapatinib_30min_R1 2 GTNTSSPYDAGADYLR 16 0 Q8ND82;Q9UJJ2 Q8ND82 ZNF280C Zinc finger protein 280C 1 GTNTS(0.032)S(0.968)PYDAGADYLR;GTNT(0.001)S(0.109)S(0.89)PYDAGADYLR 182.09 1.6443999999999999e-06 16356500.0 70876.0 65441.0 79220.0 63395.0 69677.0 66871.0 60107.0 47026.0 74459.0 51166.0 True False 69865.29524293343 65289.47538518306 72706.83739804332 68057.2797795205 65578.73585025257 64011.083213914615 63219.04635419023 49210.99963685332 66072.64333196987 60009.97492559055 1.164228035915079 1.0879770482513755 1.2115791997613108 1.1340994536976263 1.0927972546491982 1.06667405366 1.0534756335522348 0.8200469954848767 1.1010276777135257 1.0 15.872914706597122 -7.006236359043763 1.3944138764587144 0.9729871569233779 1.1465012739752733 0.47402346536489415 0.07338821104322808 0.34213758298857677 1.3521004789418671 0.03719447003309394 0.027148699176057122 9.857428620678231e-08 7.006236359043763 0.17351411705189546 GTPAGT(ph)TPGASQAPK ddPTM_PC-9_AZD4547_30min_R2 2 GTPAGTTPGASQAPK 15 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 GTPAGT(0.916)T(0.083)PGAS(0.001)QAPK;GTPAGT(0.863)T(0.137)PGASQAPK 220.52 8.1858e-18 19005500.0 62760.0 67055.0 82303.0 114361.0 93302.0 96440.0 85707.0 124334.0 102733.0 105804.0 True False 82716.374510905 88729.21741800614 81211.60844417514 87996.83830983708 80348.62780975096 90409.59155447765 93334.75696354044 105121.03721108662 108163.25664642366 102099.83416423104 0.8101518987567885 0.8690436977133792 0.7954137154967708 0.8618705312321192 0.7869613938893131 0.8855018452728411 0.9141518958141335 1.0295906753579624 1.0593871922694742 1.0 16.639620997355408 -7.510698447179195 1.7077295799335666 1.0394782854046358 0.8294818754807529 0.8824290134614484 0.03194455522081493 0.10914629216774245 0.6202821064499285 0.01919058232476039 0.00950874751667121 3.085329508388607e-08 7.510698447179195 -0.2099964099238829 GTPAGT(ph)TPGASQAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTPAGTTPGASQAPK 15 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 GT(0.001)PAGT(0.913)T(0.086)PGAS(0.001)QAPK 111.88 0.00092129 6080800.0 24078.0 29540.0 32024.0 28873.0 33188.0 25352.0 29581.0 28513.0 24235.0 20039.0 True False 28153.929837822692 32472.535976941148 32787.57361169632 27255.339417529005 26685.04964205142 24022.496490354668 26778.873532106107 27764.563962020715 24589.39102688449 23671.912071363295 1.1893390678770492 1.3717749491062137 1.3850834488085375 1.1513788719459086 1.1272874604131882 1.014810143681443 1.1312509716737842 1.1728906341963157 1.0387581262027032 1.0 14.53088862235463 -5.907720135546696 4.471591258487762 1.092296034831031 1.3199491231657592 0.6798481554642429 0.07153947197869252 0.12443088902087174 4.453660197382012 0.02057857308329464 0.03126714115381624 1.236744149132639e-06 5.907720135546696 0.22765308833472808 GTPAGTT(ph)PGASQAPK ddPTM_PC-9_Lapatinib_30min_R1 2 GTPAGTTPGASQAPK 15 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 GTPAGT(0.009)T(0.989)PGAS(0.002)QAPK;GTPAGT(0.014)T(0.985)PGAS(0.001)QAPK 119.17 0.000248 17591700.0 120192.0 119240.0 130033.0 109394.0 103010.0 92492.0 87439.0 73131.0 99679.0 72923.0 True False 118478.04003948694 118963.90710608358 119342.18868189529 117439.19968768596 96951.1543254521 88536.33276938277 91966.16357768704 76528.9332378412 88452.10135359626 85527.64338621043 1.3852601959869864 1.3909410150457164 1.3953639309689756 1.3731139434928077 1.1335651315406579 1.0351779759625346 1.0752799906154633 0.8947859453143766 1.0341931316192132 1.0 16.384103168326234 -6.423348230224397 1.8486565031124138 0.9986079004426764 1.3977487969980176 0.943119444003877 0.043894196436963726 0.0737669450844096 0.5014665772693343 0.016145689201003108 0.01887026758574529 3.772695636638983e-07 6.423348230224397 0.39914089655534113 GTPAGTTPGAS(ph)QAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTPAGTTPGASQAPK 15 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 GTPAGT(0.016)T(0.384)PGAS(0.6)QAPK 150.12 0.00013753 5209200.0 31195.0 31575.0 36269.0 31048.0 40409.0 30251.0 30805.0 35862.0 25970.0 20032.0 True False 36475.6973706653 34709.55732809468 37133.79051094845 29308.481218974142 32491.146528433652 28664.58430615805 27886.92739111352 34920.66049892984 26349.762119586958 23663.643026775248 1.5414235808659429 1.4667884099173172 1.5692338863011002 1.238544766155059 1.3730407651801604 1.2113343779621875 1.1784714365222488 1.4757094019470018 1.1135124921286375 1.0 14.530384573771416 -1.522878745401221 0.09439075432311397 0.820506066003176 2.895302913283144 0.6304411205582883 0.11261343469688397 97.47786850514105 0.6600012801237622 1.7859374952332339 26.166149056803878 0.029999999991649675 1.522878745401221 2.074796847279968 GTPCERPVR ddPTM_PC-9_Lapatinib_30min_R1 1 GTPCERPVR 9 1 P49585;C9JEJ2;C9J050;H7C1T3;C9J2E1;C9JVS0;C9JPY0;F8WAZ5 P49585 PCYT1A Choline-phosphate cytidylyltransferase A 0 104.44 0.0035039000000000003 1311500.0 1238.5 2511.3 3049.8 2301.8 2945.5 2160.3 1138.9 2377.9 2028.9 2643.3 False True 1220.8387628869166 2505.4852391438117 2799.057216568448 2471.082050579704 2772.2514810758103 2067.909004905264 1197.8666693195016 2488.385914950738 1800.3839167358346 3100.190883024146 0.3937947077942581 0.8081712816017909 0.902866088631952 0.7970741621461823 0.8942196095911229 0.6670263486769817 0.3863848112962056 0.802655710194009 0.5807332466508038 1.0 11.598141331617795 -11.609964186872759 2.4367140513098664 1.4816366235994138 0.7046228224931218 0.20808327895783962 0.1785438306129716 15035774.134050831 4519444.1735529555 40203628.65509827 0.04740702760867948 2.4549113461353004e-12 11.609964186872759 -0.777013801106292 GTPGPDSSGSLGS(ph)GEFTGVK ddPTM_PC-9_AZD4547_30min_R2 2 GTPGPDSSGSLGSGEFTGVK 20 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;M0R2S2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 GTPGPDS(0.005)S(0.005)GS(0.067)LGS(0.922)GEFTGVK;GTPGPDS(0.009)S(0.009)GS(0.242)LGS(0.738)GEFT(0.002)GVK 129.42 3.1283e-05 9776300.0 42468.0 57258.0 84483.0 79707.0 79897.0 93503.0 62061.0 93736.0 85208.0 85461.0 True False 55971.94061072516 75765.52875878304 83362.7002197885 61331.78261087419 68804.68067260813 87656.24262876723 67584.3087719124 79251.25503899493 89711.92092442026 82469.03640230378 0.6787024931112398 0.9187148542536689 1.0108363557581201 0.7436946675559905 0.8343092592589825 1.0628988339473133 0.8195113186750467 0.9609819454223796 1.0878255020076135 1.0 16.331564930255468 -7.33411676836199 0.5332063373123044 1.0345675335608928 0.8333402276930922 0.2870168018995436 0.11041286020269686 1.3299447421931478 0.8026708622267313 0.1079943017568744 0.08671081117583565 4.633223299348006e-08 7.33411676836199 -0.20122730586780058 GTPGPDSSGSLGS(ph)GEFTGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTPGPDSSGSLGSGEFTGVK 20 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;M0R2S2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 GTPGPDSSGS(0.002)LGS(0.998)GEFTGVK 160.47 8.237299999999999e-21 0.0 11779.0 19488.0 14573.0 12720.0 15537.0 13829.0 14206.0 11393.0 12450.0 10501.0 True False 13772.952054145424 21422.63984829483 14920.475588410261 12007.339638796415 12492.636383287725 13103.782895436841 12860.304837466598 11093.94582188132 12632.057696914035 12404.748174129743 1.110296788037107 1.7269709588278475 1.2028035860919046 0.9679631920168981 1.0070850458166716 1.0563521896208214 1.0367243781930957 0.8943305955229209 1.0183243963999487 1.0 13.59860482726493 -5.528210862108655 5.313118024235858 1.001378777806807 1.4318817839059752 0.5783366641703218 0.14442449705241167 0.09960173112924513 8.932746412525415 0.036277790482073226 0.06874372683981425 2.9633922304276765e-06 5.528210862108655 0.43050300609916814 GTPGPDSSGSLGS(ph)GEFTGVK ddPTM_PC-9_Lapatinib_30min_R1 1 GTPGPDSSGSLGSGEFTGVK 20 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;M0R2S2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 GTPGPDSSGS(0.001)LGS(0.999)GEFTGVK 174.15 6.898999999999999e-29 0.0 14017.0 22363.0 29315.0 22132.0 22935.0 26662.0 24778.0 29880.0 26144.0 20680.0 True False 13817.115009597012 22311.219847478627 26904.833859172406 23759.66111018769 21586.008391944888 25521.728412157627 26060.88360031487 31268.333882302904 23199.387411475025 24254.510445632106 0.5696719808288392 0.9198792075185571 1.1092713629277802 0.9795976366311887 0.8899791418314206 1.0522466932229395 1.0744757623012782 1.2891760463437385 0.9564978630872719 1.0 14.56596543994029 -4.7915091698882195 2.7471827061912553 1.047567910343028 0.4843705966593865 0.6626193123903619 0.10182519208631156 0.27075487522099645 2.821483665058661 0.027671245087944062 0.34833583385608546 1.616184100911321e-05 4.7915091698882195 -0.5631973136836415 GTPGS(ph)PSGTQEPR ddPTM_PC-9_AZD4547_30min_R2 3 GTPGSPSGTQEPR 13 0 Q5SXM2 Q5SXM2 SNAPC4 snRNA-activating protein complex subunit 4 1 GT(0.026)PGS(0.92)PS(0.047)GT(0.008)QEPR;GT(0.07)PGS(0.8)PS(0.101)GT(0.029)QEPR;GT(0.041)PGS(0.414)PS(0.414)GT(0.131)QEPR 96.866 0.0031555999999999997 25060600.0 32474.800000000003 29038.6 46213.8 57881.0 47094.2 42235.4 39156.0 47392.3 36837.9 47198.0 True False 42801.11088219784 38424.75956922689 45600.9748164395 44537.429702535635 40555.983235064414 39594.413761302225 42640.80814477696 40068.909001712935 38785.076187936626 45545.61238595312 0.9397416927782549 0.8436544719964639 1.0012155381734082 0.9778643291723875 0.890447643812391 0.869335413162952 0.936222083994373 0.8797534362293639 0.8515655879049826 1.0 15.475024458957343 -6.300427955471555 24.790877971381704 0.8983641645271505 0.9380213238773325 0.08798758277156027 0.05449211780866209 1154.1871716049804 733886.0581938053 0.016963873523965365 0.019235501148788636 5.00693605029718e-07 6.300427955471555 0.03965715935018199 GTPGS(ph)PSGTQEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GTPGSPSGTQEPR 13 0 Q5SXM2 Q5SXM2 SNAPC4 snRNA-activating protein complex subunit 4 1 GT(0.03)PGS(0.664)PS(0.296)GT(0.01)QEPR;GT(0.017)PGS(0.411)PS(0.286)GT(0.286)QEPR;GT(0.012)PGS(0.625)PS(0.313)GT(0.05)QEPR;GT(0.001)PGS(0.696)PS(0.291)GT(0.012)QEPR 132.24 5.8488e-05 40320000.0 47946.4 50993.3 59507.9 56717.8 74803.6 58359.6 64952.8 61862.3 55240.8 45565.3 True False 56062.778535434096 56055.57782102075 60926.79402096748 53540.08554758862 60146.37156213561 55299.11983979578 58800.000566450835 60238.48017352488 56048.592194673816 53825.92819528366 1.0415571159689994 1.0414233381660933 1.1319227752082872 0.9946894989593493 1.1174237691530557 1.0273695539288665 1.0924103408513635 1.1191350004216574 1.041293556356821 1.0 15.716013672552021 -3.2688536448442864 20.683745908360297 1.0651679053245158 1.0431619761270245 0.0 0.048140960732908904 0.0 0.0 0.010204332742935373 0.0 0.0005384512074171526 3.2688536448442864 -0.022005929197491225 GTPGS(ph)PSGTQEPR ddPTM_PC-9_Lapatinib_30min_R1 3 GTPGSPSGTQEPR 13 0 Q5SXM2 Q5SXM2 SNAPC4 snRNA-activating protein complex subunit 4 1 GT(0.067)PGS(0.569)PS(0.311)GT(0.053)QEPR;GT(0.002)PGS(0.891)PS(0.097)GT(0.009)QEPR;GT(0.002)PGS(0.333)PS(0.333)GT(0.333)QEPR 109.44 0.0007864 21387600.0 24196.8 20061.0 25200.3 21964.9 20856.6 22736.7 20578.4 22281.5 25983.600000000002 17316.3 True False 23851.749194850345 20014.549987044174 23128.428609971095 23580.272018758424 19629.855793653285 21764.304342836393 21643.848861115504 23316.779832614877 23057.053348561916 20309.39938248062 1.174419230507892 0.9854821213624471 1.1388041652242182 1.161052159873292 0.9665404389352092 1.0716370254460015 1.0657060040774033 1.1480782564514682 1.1352897697433382 1.0 14.309859954450411 -10.493557269663727 12.408341599557641 0.9999982477940164 1.0905390495951133 0.14312107265275997 0.06858387013150805 0.0 0.0 0.06582700405214321 0.015965393572055783 3.209539539864347e-11 10.493557269663727 0.09054080180109692 GTPGSPS(ph)GTQEPR ddPTM_PC-9_AZD4547_30min_R2 1 GTPGSPSGTQEPR 13 0 Q5SXM2 Q5SXM2 SNAPC4 snRNA-activating protein complex subunit 4 1 GT(0.002)PGS(0.154)PS(0.839)GT(0.005)QEPR 147.7 0.00011129 13217000.0 6792.6 9677.6 13701.0 14782.0 11630.0 13808.0 9036.5 13272.0 12418.0 9948.8 True False 8952.505505142964 12805.694944217372 13519.31578792563 11374.238279623394 10015.375248412745 12944.583577190251 9840.7309939799 11221.117360219574 13074.390128150537 9600.495540179041 0.9325045220505366 1.333857704597044 1.4081893722408318 1.1847553318493884 1.0432144055999393 1.3483245237723267 1.025023234769023 1.168806059359964 1.3618453415693905 1.0 13.228893158715467 -5.981084778186336 24.98406597090866 1.164171056010069 1.2458714089697496 0.02714169214447415 0.1631690486644577 854.1289115172191 1128162.9754357592 0.04529728581774896 0.06717517607574242 1.0445163003480377e-06 5.981084778186336 0.08170035295968048 GTPKPPGPPAQPPGPPNAS(ph)SNPDLRR ddPTM_PC-9_Lapatinib_30min_R1 1 GTPKPPGPPAQPPGPPNASSNPDLRR 26 2 Q8N4C8;Q8N4C8-4 Q8N4C8 MINK1 Misshapen-like kinase 1 1 GTPKPPGPPAQPPGPPNAS(0.5)S(0.5)NPDLRR 97.12799999999999 1.228e-09 13832000.0 67485.0 48241.0 42416.0 39599.0 38574.0 39492.0 32133.0 28935.0 39819.0 35230.0 True False 66522.65152476664 48129.3009284182 38928.720210494896 42511.24255839157 36305.153159401896 37803.0192203484 33796.6895120235 30279.425732410815 35334.16490734105 41319.45855897579 1.609959419720324 1.1648095741555429 0.9421401336837809 1.0288431659314878 0.8786454233804416 0.9148962870941705 0.8179364079465139 0.7328127421900411 0.8551458837948747 1.0 15.33453372912032 -1.5228787493864375 0.6979114154229431 0.8529909974566021 94.65740444304352 0.8960529332769606 0.07565131896827137 81.01214360861702 0.43363666110418075 0.03033484935989225 11853.898745840714 0.029999999716360665 1.5228787493864375 93.80441344558692 GTPKPPGPPAQPPGPPNASS(ph)NPDLR ddPTM_PC-9_AZD4547_30min_R2 1 GTPKPPGPPAQPPGPPNASSNPDLR 25 1 Q8N4C8;Q8N4C8-4 Q8N4C8 MINK1 Misshapen-like kinase 1 1 GTPKPPGPPAQPPGPPNAS(0.365)S(0.635)NPDLR 161.31 1.778e-08 5867600.0 16490.0 22422.0 22685.0 27955.0 28868.0 25474.0 22333.0 32946.0 24354.0 27813.0 True False 21733.476986692513 29669.473013892057 22384.18207788432 21510.406650444595 24860.17649795177 23881.106752994223 24320.593735246293 27854.952723763876 25641.3027203236 26839.275335618335 0.8097639267424658 1.1054498544719564 0.8340084371867644 0.8014525869816682 0.926261092636875 0.8897820993438548 0.9061568701510542 1.0378429512512821 0.9553649418505384 1.0 14.712058098635104 -7.702736349759513 8.41834723570966 0.9972712815670433 0.8988083968710129 0.23981737877780307 0.08282287143333933 0.4039666053746342 52.30931797799071 0.0392693182277942 0.022507359400135627 1.9827303307247497e-08 7.702736349759513 -0.09846288469603037 GTPKPPGPPAQPPGPPNASS(ph)NPDLR ddPTM_PC-9_Lapatinib_30min_R1 2 GTPKPPGPPAQPPGPPNASSNPDLR 25 1 Q8N4C8;Q8N4C8-4 Q8N4C8 MINK1 Misshapen-like kinase 1 1 GTPKPPGPPAQPPGPPNAS(0.37)S(0.63)NPDLR;GTPKPPGPPAQPPGPPNAS(0.41)S(0.59)NPDLR 156.56 8.3378e-26 4631700.0 24516.0 22901.0 21439.0 20724.0 21932.0 21115.1 16105.0 15195.0 19196.5 17621.5 True False 24166.39734431623 22847.974141533232 19676.36817693323 22248.112093237374 20642.002879971016 20212.056394702166 16938.838097629803 15901.015172074724 17034.38802189337 20667.352795827184 1.1693029863599906 1.1055104331574734 0.9520507232501475 1.0764858137869187 0.9987734318900635 0.9779702603607296 0.8195939879174955 0.7693784167310096 0.824217217859303 1.0 14.335065990716798 -6.951280217858398 1.7379161083895234 0.8333240463813388 1.066235922547664 0.6048526802253689 0.07842660622010186 0.23642018745787532 1.4519869185732943 0.036237863078805846 0.02858895112008652 1.1187158266096759e-07 6.951280217858398 0.23291187616632525 GTPKPPGPPAQPPGPPNASS(ph)NPDLRR ddPTM_PC-9_AZD4547_30min_R2 1 GTPKPPGPPAQPPGPPNASSNPDLRR 26 2 Q8N4C8;Q8N4C8-4 Q8N4C8 MINK1 Misshapen-like kinase 1 1 GTPKPPGPPAQPPGPPNAS(0.184)S(0.816)NPDLRR 88.684 2.5308000000000004e-07 20415000.0 16651.0 14236.0 17742.0 30355.0 27922.0 20367.0 16115.0 19167.0 13271.0 17085.0 True False 21945.671637684485 18837.5085998469 17506.729487583143 23357.123730074945 24045.512268803148 19093.448270323996 17549.20378110839 16205.180563843322 13972.477966716535 16486.85935026928 1.3311007980016551 1.1425771397473121 1.061859576505528 1.4167115297003765 1.4584653000275893 1.158100998175383 1.0644358278474524 0.9829149518145579 0.8474917914847332 1.0 14.009028979578396 -7.3808560123146485 2.0047757335413534 0.9367531812439837 1.268915073689133 0.6065225673262611 0.11836960070808546 0.2601570972945007 2.041018046908104 0.07112810577392978 0.04111018708398728 4.160485259802443e-08 7.3808560123146485 0.3321618924451494 GTPLT(ph)PPACACSSLQVEVER ddPTM_PC-9_AZD4547_30min_R2 1 GTPLTPPACACSSLQVEVER 20 0 Q8TD19 Q8TD19 NEK9 Serine/threonine-protein kinase Nek9 1 GT(0.013)PLT(0.987)PPACACSSLQVEVER 171.33 3.4846e-08 11020000.0 77408.0 77883.0 109140.0 139120.0 128480.0 95113.0 97008.0 136080.0 89289.0 106180.0 True False 102022.1338135774 103057.15666492538 107692.73228919084 107048.03338257388 110642.76972623137 89165.56907425394 105641.52407060252 115051.9628073146 94008.6342528936 102462.67051867658 0.9957005150961893 1.005801977864128 1.051043582448507 1.0447515455207805 1.0798349210121725 0.870224918234989 1.0310245042007422 1.1228671107722425 0.9174915486490076 1.0 16.644738873272857 GTPLT(ph)PPACACSSLQVEVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTPLTPPACACSSLQVEVER 20 0 Q8TD19 Q8TD19 NEK9 Serine/threonine-protein kinase Nek9 1 GT(0.002)PLT(0.953)PPACACS(0.029)S(0.016)LQVEVER 76.068 0.0054235 8388400.0 8671.6 9887.9 9893.3 10431.0 10428.0 12587.0 12496.0 9053.4 10131.0 8169.4 True False 10139.530608093002 10869.505365145444 10129.193792549186 9846.584887758281 8384.708258024353 11926.915561852878 11312.288416794498 8815.757842870218 10279.146709031016 9650.447551065186 1.0506798316285169 1.1263213760428863 1.0496087087102148 1.0203241700092391 0.8688413893404223 1.2358924805032925 1.1722035021625379 0.9135076685533784 1.0651471503926713 1.0 13.236380135304978 -7.771098054549642 24.99997649509093 0.9919956061865626 1.0720231788429684 0.12726450551667112 0.09814617789260444 490.3953344494538 1269290.2557187185 0.055317823731194954 0.02708825271308597 1.6939552978295877e-08 7.771098054549642 0.08002757265640581 GTPPLTPSDS(ph)PQTR ddPTM_PC-9_AZD4547_30min_R2 1 GTPPLTPSDSPQTR 14 0 Q6NZY4-2;Q6NZY4 Q6NZY4-2 ZCCHC8 Zinc finger CCHC domain-containing protein 8 1 GTPPLT(0.001)PS(0.081)DS(0.917)PQT(0.001)R 157.37 0.00038656 7475500.0 6207.8 4893.7 8925.2 9214.8 10509.0 7206.6 5137.5 10464.0 5667.2 8565.1 True False 8181.7512697386155 6475.49282348067 8806.846016377913 7090.47022724081 9050.006748544236 6755.970162759217 5594.727547343739 8847.029238798796 5966.756622181896 8265.238456013538 0.9898989984718252 0.7834611013272457 1.0655283647588314 0.8578663840100098 1.0949480522198032 0.8173956745124246 0.6768985041530392 1.0703900783844855 0.721909797755522 1.0 13.012840727209996 GTPS(ph)QSPVVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTPSQSPVVGR 11 0 P52594-2;P52594-3;P52594;P52594-4;C9J2I0;B8ZZY2 P52594-2 AGFG1 Arf-GAP domain and FG repeat-containing protein 1 1 GT(0.008)PS(0.496)QS(0.496)PVVGR 69.229 0.035238 82704000.0 11393.0 10068.0 22553.0 14563.0 15580.0 15875.0 16291.0 11137.0 14574.0 8536.5 True False 13321.609877992943 11067.484502906016 23090.749052728806 13747.082323883022 12527.210841965798 15042.487053659686 14747.798543373814 10844.665550626905 14787.117178700813 10084.099875103184 1.321050965677453 1.0975183348025666 2.28981756812405 1.3632433726507847 1.2422735789135186 1.491703497582204 1.4624804123355541 1.0754222672269933 1.466379484718214 1.0 13.299794691692586 -8.543505949866498 0.4566940835628287 0.995879635307042 1.5076933356607933 0.15414251761092534 0.3178227477156139 2.3447241887617998 1.2236226225274154 0.4306368437346838 0.2121167443465278 2.8608431665959174e-09 8.543505949866498 0.5118137003537513 GTPSQS(ph)PVVGR ddPTM_PC-9_AZD4547_30min_R2 5 GTPSQSPVVGR 11 0 P52594-2;P52594-3;P52594;P52594-4;C9J2I0;B8ZZY2 P52594-2 AGFG1 Arf-GAP domain and FG repeat-containing protein 1 1 GT(0.073)PS(0.163)QS(0.763)PVVGR;GT(0.002)PS(0.027)QS(0.971)PVVGR;GT(0.001)PS(0.123)QS(0.876)PVVGR;GT(0.016)PS(0.132)QS(0.852)PVVGR;GT(0.166)PS(0.273)QS(0.561)PVVGR 118.73 0.0010348 325755600.0 37399.3 46513.5 111599.0 202875.0 148147.0 101206.0 85560.0 153144.0 87107.0 101156.0 True False 49291.499446234666 61548.07925393222 110119.1243425087 156105.3031375046 127579.34625336227 94877.57282105404 93174.67424831717 129479.11369902543 91711.29818753504 97614.55922949027 0.5049605287911113 0.6305215096985037 1.1281014349879959 1.59920102461871 1.3069704689586854 0.9719612890736757 0.9545161601279681 1.3264323961615407 0.9395247892470961 1.0 16.574808721617245 -5.238826134161951 4.188201108474485 1.1754482110546272 0.5435343503971963 0.5803662827629299 0.19979018588217465 0.14618891179742335 6.172423938632919 0.05556634584669784 0.15032812059493508 5.769974128158871e-06 5.238826134161951 -0.6319138606574308 GTPSQS(ph)PVVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GTPSQSPVVGR 11 0 P52594-2;P52594-3;P52594;P52594-4;C9J2I0;B8ZZY2 P52594-2 AGFG1 Arf-GAP domain and FG repeat-containing protein 1 1 GT(0.002)PS(0.023)QS(0.976)PVVGR;GT(0.013)PS(0.092)QS(0.894)PVVGR;GT(0.102)PS(0.257)QS(0.641)PVVGR 96.70700000000001 0.0056932 188776300.0 23672.2 31383.7 190878.0 45126.6 55203.0 58420.0 52610.0 44925.0 46993.0 38976.4 True False 27679.435912738052 34499.26632835236 195429.25542884652 42598.30290441119 44386.36842805126 55356.352357467666 47626.39993658438 43745.76635197213 47680.18372297845 46042.512782987375 0.6011712706298157 0.7492915621473156 4.2445393097888715 0.9251950063018973 0.9640301049001814 1.2022878207881333 1.0344005367618043 0.950116831332805 1.035568669931416 1.0 15.490678950652745 GTPSQS(ph)PVVGR ddPTM_PC-9_Lapatinib_30min_R1 5 GTPSQSPVVGR 11 0 P52594-2;P52594-3;P52594;P52594-4;C9J2I0;B8ZZY2 P52594-2 AGFG1 Arf-GAP domain and FG repeat-containing protein 1 1 GT(0.005)PS(0.058)QS(0.936)PVVGR;GT(0.005)PS(0.056)QS(0.938)PVVGR;GT(0.001)PS(0.02)QS(0.979)PVVGR;GT(0.007)PS(0.078)QS(0.915)PVVGR;GT(0.062)PS(0.243)QS(0.695)PVVGR 113.52 0.0015527000000000002 320576400.0 85646.0 75672.0 111346.0 76504.0 84488.0 85374.0 74248.0 78582.0 105678.0 62043.0 True False 84424.6723344473 75496.78613327385 102191.56168798947 82130.35936986239 79518.58194979897 81722.75303651436 78092.19814174579 82233.20659769519 93775.43080132564 72767.04988289907 1.1602046870157352 1.0375133560418848 1.4043658751102597 1.128675128399891 1.0927828196658358 1.1230736049905463 1.073180763373206 1.130088504756337 1.2887073332261576 1.0 16.15099770179107 -5.9607901364325295 24.999830028613324 1.1214221029870641 1.1980670584630537 0.10688981981778867 0.10757471686120267 393.1415415767669 250661.00300749243 0.030123679572446188 0.044680549675889775 1.0944851251543635e-06 5.9607901364325295 0.0766449554759896 GTQEVAPPTPLTPT(ph)SHTANTSPRPVSGMER ddPTM_PC-9_AZD4547_30min_R2 1 GTQEVAPPTPLTPTSHTANTSPRPVSGMER 30 1 P48730-2;H7BYT1;P48730 P48730-2 CSNK1D Casein kinase I isoform delta 1 GTQEVAPPT(0.005)PLT(0.026)PT(0.204)S(0.204)HT(0.179)ANT(0.179)S(0.179)PRPVS(0.026)GMER 53.25899999999999 0.0036349000000000004 25377000.0 13152.0 20649.0 19346.0 34503.0 32152.0 25487.0 18950.0 23401.0 21429.0 37426.0 True False 17334.0624214057 27323.385436796765 19089.45939954815 26548.866416036126 27688.249783918007 23893.293860939157 20636.51328898567 19784.91315148418 22561.69319182944 36115.72713158784 0.47995883782843285 0.7565508881281517 0.5285636180048543 0.7351054104297885 0.7666535324911423 0.6615758772870284 0.5713996346742909 0.5478198757953217 0.6247054949115601 1.0 15.140339596545589 -10.59848380934643 3.567912689332569 1.000182410079099 0.6348431861888562 0.5773282574364462 0.09483633499867723 43720427.32066876 74925456.63901156 95320.24359477405 0.024095016084725078 2.520671149409216e-11 10.59848380934643 -0.36533922389024287 GTQEVAPPTPLTPT(ph)SHTANTSPRPVSGMER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GTQEVAPPTPLTPTSHTANTSPRPVSGMER 30 1 P48730-2;H7BYT1;P48730 P48730-2 CSNK1D Casein kinase I isoform delta 1 GTQEVAPPT(0.003)PLT(0.016)PT(0.186)S(0.186)HT(0.186)ANT(0.186)S(0.186)PRPVS(0.052)GMER;GTQEVAPPT(0.001)PLT(0.009)PT(0.199)S(0.199)HT(0.199)ANT(0.199)S(0.168)PRPVS(0.027)GMER 51.586000000000006 0.0068785 33978200.0 46280.0 52570.0 71705.0 75188.0 101641.0 78731.0 70832.0 68024.0 69912.0 51511.0 True False 54114.28992833439 57788.802176973455 73414.71914272696 70975.4601227848 81725.17568602363 74602.2077619956 64122.28018072882 66238.44207738583 70934.33073949027 60849.53653914839 0.8893130992627892 0.9496999560513372 1.2064959458728923 1.166409214589856 1.3430698134150063 1.2260111087945467 1.0537841999745532 1.08856115994853 1.1657332951723254 1.0 15.892958654235066 -5.176503163631483 4.574602269834931 1.1652104010687947 0.9055004160064904 0.51831948264377 0.09141393198267743 0.1748435912969932 6.43515602552274 0.02489196542135606 0.07152167955208545 6.660346695307593e-06 5.176503163631483 -0.25970998506230425 GTQEVAPPTPLTPT(ph)SHTANTSPRPVSGMER ddPTM_PC-9_Lapatinib_30min_R1 2 GTQEVAPPTPLTPTSHTANTSPRPVSGMER 30 1 P48730-2;H7BYT1;P48730 P48730-2 CSNK1D Casein kinase I isoform delta 1 GTQEVAPPT(0.001)PLT(0.036)PT(0.186)S(0.186)HT(0.186)ANT(0.186)S(0.186)PRPVS(0.031)GMER;GTQEVAPPT(0.005)PLT(0.029)PT(0.208)S(0.208)HT(0.208)ANT(0.159)S(0.159)PRPVS(0.025)GMER 53.843999999999994 0.0025006 43422000.0 53447.0 70523.0 81188.0 57118.0 65019.0 67334.0 68238.0 66215.0 64481.0 48324.0 True False 52684.83597902059 70359.70832642032 74513.03603474291 61318.648260062364 61194.7102522723 64454.281783220395 71771.02974890177 69291.59062974181 57218.47076496794 56676.73901231746 0.9295671715969875 1.2414212523964931 1.3147022452817745 1.0819014877820703 1.0797147351574505 1.1372263631683652 1.2663224984292742 1.2225754663598902 1.0095582731485795 1.0 15.790469132404903 -8.277923533604172 21.797911282454066 1.004778731233082 1.164719397406409 0.25243217381921046 0.10593926021379614 243.40036340181098 321845.4038368017 0.10198545428836593 0.02682423345004554 5.27322699159279e-09 8.277923533604172 0.15994066617332692 GTQEVAPPTPLTPTS(ph)HTANTSPRPVSGMER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTQEVAPPTPLTPTSHTANTSPRPVSGMER 30 1 P48730-2;H7BYT1;P48730 P48730-2 CSNK1D Casein kinase I isoform delta 1 GTQEVAPPTPLT(0.008)PT(0.044)S(0.36)HT(0.36)ANT(0.107)S(0.107)PRPVS(0.014)GMER 59.673 0.00053833 24307000.0 17811.0 23889.0 38785.0 28151.0 29713.0 25648.0 29900.0 24819.0 23650.0 22904.0 True False 20826.05051671484 26260.542043099107 39709.781492931616 26573.790736773408 23890.9509465552 24302.973729276448 27067.655542746117 24167.527547904196 23995.836508595745 27056.31389203576 0.7697297791494485 0.9705883125058328 1.4676715258178796 0.9821659684616393 0.8830083448132856 0.898236686130043 1.000419186839553 0.893230602082056 0.886884909908556 1.0 14.72367768183815 -5.989563849623805 24.99654995738878 0.9246544948045546 1.0870328218931793 0.12576921179643819 0.16594875906198484 413.8403862821132 991215.9300111076 0.04853140355435317 0.07190137013499637 1.0243211743683016e-06 5.989563849623805 0.16237832708862465 GTQEVAPPTPLTPTSHTANT(ph)SPRPVSGMER ddPTM_PC-9_AZD4547_30min_R2 1 GTQEVAPPTPLTPTSHTANTSPRPVSGMER 30 1 P48730-2;H7BYT1;P48730 P48730-2 CSNK1D Casein kinase I isoform delta 1 GTQEVAPPT(0.001)PLT(0.026)PT(0.085)S(0.085)HT(0.173)ANT(0.21)S(0.21)PRPVS(0.21)GMER 43.306000000000004 0.029854000000000002 28884000.0 9674.8 14802.0 28176.0 28729.0 34266.0 25998.0 21420.0 34519.0 26141.0 22948.0 True False 12751.185151658741 19586.457031113638 27802.36783012864 22105.972908625394 29508.757374214176 24372.34095015876 23326.33850396165 29184.881717707893 27522.759892090773 22144.59750482759 0.5758147172861888 0.8844801548930266 1.2554921273266602 0.9982558004861558 1.3325488245058947 1.100599861652284 1.0533647540388322 1.3179233314737602 1.2428656644624372 1.0 14.434667154913734 -4.940072731851177 2.520327462507719 1.168474720288954 0.537356044643277 0.707008569641373 0.11910874000347751 0.18899235386720856 1.9705734449836778 0.03042989175405303 0.2233200957122845 1.147961354844516e-05 4.940072731851177 -0.631118675645677 GTQEVAPPTPLTPTSHTANTS(ph)PRPVSGMER ddPTM_PC-9_AZD4547_30min_R2 1 GTQEVAPPTPLTPTSHTANTSPRPVSGMER 30 1 P48730-2;H7BYT1;P48730 P48730-2 CSNK1D Casein kinase I isoform delta 1 GTQEVAPPT(0.046)PLT(0.046)PT(0.075)S(0.075)HT(0.075)ANT(0.075)S(0.42)PRPVS(0.189)GMER 50.088 0.018453999999999998 13839000.0 16508.0 14504.0 27534.0 41635.0 28728.0 34191.0 26424.0 37525.0 27243.0 31348.0 True False 21757.20061226925 19192.13435882127 27168.88116960401 32036.694004337685 24739.61308137587 32053.031364984923 28775.684809929164 31726.373488716035 28683.009362313198 30250.5160615886 0.7192340311805799 0.6344398991325306 0.8981295100648686 1.0590461973975092 0.8178244969774136 1.059586266221921 0.9512460796154104 1.048787842961841 0.9481824807192037 1.0 14.884672133941443 -5.390706688923167 4.029844757885326 0.9805069324284451 0.6781103595057181 0.7421540731418634 0.07107928466068998 0.10193615955411968 2.7861270760358843 0.01793636877090664 0.040070489129068264 4.067179230219049e-06 5.390706688923167 -0.30239657292272704 GTQEVAPPTPLTPTSHTANTS(ph)PRPVSGMER ddPTM_PC-9_Lapatinib_30min_R1 1 GTQEVAPPTPLTPTSHTANTSPRPVSGMER 30 1 P48730-2;H7BYT1;P48730 P48730-2 CSNK1D Casein kinase I isoform delta 1 GTQEVAPPT(0.005)PLT(0.011)PT(0.138)S(0.157)HT(0.133)ANT(0.133)S(0.404)PRPVS(0.02)GMER 48.088 0.0079835 3724300.0 4762.5 5181.2 6153.2 5607.2 6185.9 6426.5 4665.2 5994.0 5858.2 4361.2 True False 4694.585876664464 5169.203249731978 5647.307648038882 6019.572193070866 5822.057523947327 6151.6535759031985 4906.74122900109 6272.503122172816 5198.38782641918 5115.02760906628 0.9178026465279304 1.010591465932593 1.1040620070220435 1.1768406063735217 1.138226021229651 1.2026628292288237 0.9592795198805951 1.226289201460992 1.0162971197272026 1.0 12.320526311798968 -5.008805167997623 2.337374184880172 1.1137769913709556 0.9111602149638405 0.322411575719724 0.08463772009410525 0.3964662707113405 3.6251797720823196 0.02137178341768769 0.13522230288846065 9.799295001059434e-06 5.008805167997623 -0.20261677640711517 GTQEVAPPTPLTPTSHTANTSPRPVS(ph)GMER ddPTM_PC-9_AZD4547_30min_R2 1 GTQEVAPPTPLTPTSHTANTSPRPVSGMER 30 1 P48730-2;H7BYT1;P48730 P48730-2 CSNK1D Casein kinase I isoform delta 1 GTQEVAPPT(0.01)PLT(0.01)PT(0.104)S(0.104)HT(0.088)ANT(0.076)S(0.253)PRPVS(0.356)GMER 44.743 0.038 13452000.0 16774.0 11748.0 24874.0 39732.0 35477.0 32617.0 26598.0 39539.0 24992.0 32891.0 True False 22107.78307912554 15545.311255338676 24544.154507617113 30572.401253280794 30551.63092759575 30577.45383380753 28965.170472846476 33429.15606583194 26313.026097820777 31739.496101241253 0.6965385653448026 0.4897781365448564 0.7733000684487001 0.9632289421282016 0.9625745421459591 0.9633881311874929 0.9125907475170572 1.0532352485748697 0.8290309970230353 1.0 14.953991603563406 -5.551415816294573 3.3941148436789095 0.9555366075133765 0.5946609439862791 0.8007492254292218 0.07247813861078865 0.0860603541810875 2.0636562063739947 0.018560040324674343 0.037304233814722164 2.8092098576413723e-06 5.551415816294573 -0.36087566352709743 GTQGATAGAS(ph)SELDASK ddPTM_PC-9_AZD4547_30min_R2 1 GTQGATAGASSELDASK 17 0 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 1 GTQGATAGAS(0.86)S(0.14)ELDASK 136.04 4.6173e-05 5058700.0 6792.5 9763.8 11285.0 12558.0 10418.0 11052.0 10772.0 12670.0 10805.0 9332.2 True False 8952.3737072231 12919.757408484485 11135.353526511983 9662.947119165909 8971.640527769898 10360.916692866938 11730.687131870915 10712.142627635765 11376.13024115531 9005.482518500616 0.9941026134725807 1.4346546542000933 1.2365082607884494 1.073007148624698 0.9962420680223193 1.1505121098821474 1.302616168292117 1.1895134553455669 1.2632449419322618 1.0 13.136587863225422 -10.735508241407736 3.6614011025795414 0.9997660924795381 1.1854193566666622 0.14860843028346526 0.13068364440525873 96903498.81020671 148607698.36022845 263474.5655591134 0.03362614248274431 1.8386190629000037e-11 10.735508241407736 0.18565326418712413 GTQGATAGAS(ph)SELDASK ddPTM_PC-9_Lapatinib_30min_R1 2 GTQGATAGASSELDASK 17 0 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 1 GTQGATAGAS(0.781)S(0.219)ELDASK;GTQGAT(0.001)AGAS(0.497)S(0.497)ELDAS(0.004)K 170.22 2.6415e-24 0.0 17686.6 16139.0 18045.9 16628.9 17041.4 21192.4 19708.1 15706.7 14780.900000000001 14332.5 True False 17434.385840674782 16101.631137077215 16562.235761188458 17851.84477838425 16039.058356681478 20286.050453897267 20728.488985526095 16436.490622127414 13116.119392222736 16809.853528144205 1.0371527515980399 0.9578686161731726 0.9852694869386477 1.0619869321583006 0.9541462291642097 1.2067951942551418 1.2331153838325266 0.9777890446581416 0.7802637524629725 1.0 14.037019533323969 -8.001787993550897 24.99878353428388 0.886430020552345 1.0602133834283909 0.316966842375911 0.10169904825300298 77.85273570189739 1088484.0042911028 0.0604863246123361 0.02836140230925347 9.95891455959463e-09 8.001787993550897 0.1737833628760459 GTQSIPNDS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 4 GTQSIPNDSPAR 12 0 J3QRX6;H9KV77;Q9NQ92 J3QRX6 COPRS Coordinator of PRMT5 and differentiation stimulator 1 GTQSIPNDS(1)PAR;GTQS(0.004)IPNDS(0.996)PAR;GTQS(0.001)IPNDS(0.999)PAR;GT(0.001)QS(0.028)IPNDS(0.971)PAR 130.66 0.00013949 68633700.0 69842.0 74011.0 93238.0 92161.0 94233.0 90700.0 82802.0 109440.0 79758.0 82539.0 True False 92050.3031961539 97933.60838601213 92001.60319937313 70914.70532325607 81150.37452998087 85028.51466187398 90171.21759127126 92528.56268101471 83973.84505081583 79649.33473291622 1.1556945642398793 1.2295596531271424 1.155083134189094 0.890336442370178 1.018845603696478 1.0675357797650848 1.1321025830741398 1.1616991276987523 1.054294368338427 1.0 16.2813746913122 -5.540145647157055 24.999766561641483 1.0538478463686223 1.19255074555932 0.4250483662612229 0.07178581038984957 236.9781756213179 343105.91132623586 0.02129217195187784 0.036888947562583436 2.8830644621452755e-06 5.540145647157055 0.13870289919069778 GTQSIPNDS(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GTQSIPNDSPAR 12 0 J3QRX6;H9KV77;Q9NQ92 J3QRX6 COPRS Coordinator of PRMT5 and differentiation stimulator 1 GTQSIPNDS(1)PAR;GTQSIPNDS(1)PAR 159.41 0.00017962 54627000.0 165923.0 269970.0 262712.0 203077.0 222162.0 175333.0 218468.0 140196.0 148399.0 162942.0 True False 194010.48677137026 296770.8374304266 268976.05042080855 191699.2540745175 178630.95090326146 166138.22882389367 197773.12946865108 136516.00354994056 150569.05463167428 192482.09475183793 1.0079404373768004 1.541810098300548 1.3974081629129829 0.9959329168859591 0.9280393126101709 0.863136018122056 1.0274884514512104 0.7092400138617934 0.7822496675641388 1.0 17.554364722768156 -5.8819046283946514 3.9082247599205746 0.882122124376617 1.3378657637781202 0.6117205949339227 0.1528590132114604 0.14051370393557408 3.9860842960976517 0.04408839540273324 0.06837183468950896 1.3124880913824593e-06 5.8819046283946514 0.4557436394015032 GTQSIPNDS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 4 GTQSIPNDSPAR 12 0 J3QRX6;H9KV77;Q9NQ92 J3QRX6 COPRS Coordinator of PRMT5 and differentiation stimulator 1 GTQSIPNDS(1)PAR;GTQSIPNDS(1)PAR;GTQSIPNDS(1)PAR;GT(0.089)QS(0.063)IPNDS(0.849)PAR 169.98 0.0010373 87754100.0 95037.0 96067.0 97555.0 80807.0 104915.0 87593.0 101037.0 96032.0 103811.0 90726.4 True False 93681.75495234883 95844.56276383901 89534.40447318992 86749.8163442498 98744.10597082617 83846.85157925596 106268.20148216226 100493.99730205187 92118.71200170717 106408.33735467114 0.8803986349311788 0.9007241833351661 0.8414228311336313 0.8152539406296967 0.9279733940555879 0.7879725749288313 0.9986830367244458 0.9444184525418708 0.8657095326531133 1.0 16.69925166840565 -7.270543428462831 24.99899334700779 0.947570957145463 0.861209591078102 0.44078198419261183 0.051309465839904006 686.890611370192 1886139.5512101117 0.020793273262552984 0.014239909394886431 5.363602339520655e-08 7.270543428462831 -0.086361366067361 GTQSTEGS(ph)PVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GTQSTEGSPVSK 12 0 A0A087WXK8;Q9H4H8-2;Q9H4H8 A0A087WXK8 FAM83D Protein FAM83D 1 GT(0.001)QS(0.002)T(0.01)EGS(0.927)PVS(0.059)K;GTQSTEGS(0.889)PVS(0.11)K;GTQS(0.001)T(0.004)EGS(0.935)PVS(0.06)K 99.991 0.007061499999999999 20839800.0 68962.0 64808.0 67741.0 81136.0 93982.0 82038.0 82702.0 77445.0 74061.0 65007.0 True False 80635.90453841376 71241.70993884915 69356.20234917308 76590.2129664613 75566.90175543186 77735.78286035488 74867.86784937105 75412.15080976019 75144.0020153536 76792.25450487109 1.0500525744207556 0.9277199946555826 0.9031666383069099 0.9973689854567693 0.9840432767947774 1.0122867646166573 0.9749403547544242 0.9820280872855041 0.9785362143598358 1.0 16.228673183322265 GTQSTEGS(ph)PVSK ddPTM_PC-9_Lapatinib_30min_R1 2 GTQSTEGSPVSK 12 0 A0A087WXK8;Q9H4H8-2;Q9H4H8 A0A087WXK8 FAM83D Protein FAM83D 1 GTQST(0.001)EGS(0.994)PVS(0.005)K;GT(0.001)QS(0.002)T(0.006)EGS(0.99)PVS(0.001)K 153.2 0.00019579 19401000.0 156269.0 130034.0 124176.0 110093.0 148019.0 133669.0 114209.0 114830.0 162466.0 121313.0 True False 154040.57540377512 129732.91426226543 113966.72861322168 118189.60647948198 139312.81343655058 127952.2884676581 120122.18319107124 120165.42100752488 144167.36823717493 142281.7904105885 1.082644342324157 0.9118026550543802 0.8009930735643904 0.8306727525596727 0.9791331205105712 0.8992878716132321 0.8442554935837513 0.84455938220034 1.0132524184658145 1.0 17.118391508294344 -8.276072459875124 24.508544785325896 1.0066262538296622 0.8948730350479898 0.2316800311603877 0.07796182899864944 1056.7696139128473 1769932.5153357608 0.07625935990032585 0.020061609462974313 5.295750795511524e-09 8.276072459875124 -0.11175321878167244 GTS(ph)GSLADVFANTR ddPTM_PC-9_AZD4547_30min_R2 1 GTSGSLADVFANTR 14 0 Q9P265 Q9P265 DIP2B Disco-interacting protein 2 homolog B 1 GT(0.028)S(0.486)GS(0.486)LADVFANTR 80.37100000000001 0.011676 3561200.0 6246.4 10874.0 13391.0 16488.0 17209.0 12881.0 10808.0 17538.0 13914.0 12406.0 True False 8232.625266808735 14388.80784734021 13213.426590476041 12686.94633706064 14819.827398962576 12075.549033733165 11769.891062129673 14827.905083147292 14649.46563400602 11971.669716092507 0.6876756093381285 1.2019048460716009 1.1037246185228737 1.0597474402427465 1.2379081406699293 1.0086770951842265 0.9831453206822437 1.2385828739674791 1.2236777309612858 1.0 13.547336761833519 -4.754664297521653 24.999998862105496 1.1188715592519987 0.6876748756435532 0.6368462905556922 0.09736497841311356 152.2319146798009 561684.3287223793 0.02449809431887164 0.23360252990450572 1.7592829852639107e-05 4.754664297521653 -0.43119668360844543 GTS(ph)PRPPEGGLGYSQLGDDDLK ddPTM_PC-9_AZD4547_30min_R2 1 GTSPRPPEGGLGYSQLGDDDLK 22 1 P21127;P21127-8;A0A0D9SEN2;A0A0D9SER5;A0A0D9SEI3;P21127-9;P21127-2;P21127-3;P21127-6;P21127-10;P21127-5;P21127-4;P21127-12;Q9UQ88-8;Q5QPR4;Q5QPR3;Q9UQ88-4;Q9UQ88-3;Q9UQ88-2;Q9UQ88;Q9UQ88-5;Q9UQ88-10 P21127;Q5QPR4 CDK11B;CDK11A Cyclin-dependent kinase 11B;Cyclin-dependent kinase 11A 1 GT(0.212)S(0.788)PRPPEGGLGYSQLGDDDLK 96.455 7.072e-05 9322200.0 41798.0 49091.0 40977.0 39871.0 43211.0 55830.0 55186.0 54528.0 45893.0 47874.0 True False 55088.8945475909 64958.70572317253 40433.61820610382 30679.356950809386 37211.89852615331 52338.941274227385 60097.44709055215 46101.95052878634 48318.81028758359 46197.945831711506 1.1924533343596504 1.4060951099384842 0.8752254559844326 0.6640848721405759 0.8054881630821357 1.1329278895837949 1.300868382968224 0.9979220872011312 1.0459081982475564 1.0 15.495541083911819 -5.261935742609495 24.99870806608373 0.9774488032642534 1.2992742296189488 0.3588488519483085 0.17187985413170376 51.75448229020371 2606711.310590439 0.05097216318423656 0.11765939223030239 5.470969043295262e-06 5.261935742609495 0.32182542635469535 GTS(ph)PSSSSRPQR ddPTM_PC-9_AZD4547_30min_R2 2 GTSPSSSSRPQR 12 1 H3BVG0;Q8N1F7;Q8N1F7-2 H3BVG0 NUP93 Nuclear pore complex protein Nup93 1 GT(0.001)S(0.905)PS(0.041)S(0.041)S(0.011)S(0.001)RPQR;GT(0.011)S(0.963)PS(0.017)S(0.006)S(0.002)S(0.002)RPQR 122.55 0.0019102000000000001 195408000.0 11077.1 11137.8 14338.5 18892.5 15032.4 15287.0 12839.5 14886.0 13278.7 14071.8 True False 14599.387382006762 14737.87603845004 14148.362121390524 14537.126011215323 12945.410738111748 14331.101473385515 13982.190626592701 12585.710746249893 13980.58497299667 13579.150565122576 1.075132594781342 1.0853312191930176 1.041918053234489 1.070547523683349 0.9533299359211349 1.0553754010353409 1.0296808006905318 0.9268407980227948 1.0295625566524875 1.0 13.729105615110457 -5.871284550083209 0.8309498626421986 0.9954920198932193 1.0888136257598282 0.39375210637988445 0.038809894881399125 0.803238486854446 1.052826607516764 0.018049864334998736 0.05176551662294148 1.3449788341202682e-06 5.871284550083209 0.09332160586660887 GTS(ph)SPDYR ddPTM_PC-9_AZD4547_30min_R2 1 GTSSPDYR 8 0 Q66K14;Q66K14-2;G3V133 Q66K14 TBC1D9B TBC1 domain family member 9B 1 GT(0.07)S(0.465)S(0.465)PDYR 104.06 0.0038641999999999995 66682000.0 31778.0 24465.0 36779.0 42601.0 38652.0 39139.0 38286.0 38097.0 32624.0 32522.0 True False 41882.742976538175 32372.832810849577 36291.28642902831 32779.99762888891 33285.83698208504 36691.632142790324 41693.379830190264 32209.984031968426 34348.43803678396 31383.41467892638 1.3345502203959334 1.0315267838775868 1.1563842494614684 1.0445006690396987 1.0606187160518297 1.1691408509294037 1.3285163598907839 1.0263377762266601 1.094477397956589 1.0 14.937714713128177 GTS(ph)SPDYR ddPTM_PC-9_Lapatinib_30min_R1 2 GTSSPDYR 8 0 Q66K14;Q66K14-2;G3V133 Q66K14 TBC1D9B TBC1 domain family member 9B 1 GT(0.04)S(0.558)S(0.403)PDYR;GT(0.078)S(0.573)S(0.349)PDYR 109.11 0.0037833 130654000.0 73308.0 94122.0 91192.0 84501.0 95957.0 89502.0 80583.0 85527.0 100019.0 67820.0 True False 72262.6144769592 93904.06629183855 83694.54577129966 90715.48542707262 90312.99791872068 85674.20809935239 84755.19344435271 89500.8966516639 88753.80697323756 79542.59663553024 0.9084769360506494 1.1805506767916263 1.0521978073558995 1.140464219979357 1.1354041952205958 1.0770858850876799 1.0655321428932847 1.1251945553369762 1.1158022333607456 1.0 16.279440038650783 -4.746555970851129 24.99946607658337 1.102267931812563 0.9084764246270227 0.5727074112239805 0.04933900975043416 548.8134992474053 921783.6250880834 0.011381687857435246 0.2552159764247008 1.7924375323468156e-05 4.746555970851129 -0.19379150718554028 GTSGS(ph)LADVFANTR ddPTM_PC-9_AZD4547_30min_R2 1 GTSGSLADVFANTR 14 0 Q9P265 Q9P265 DIP2B Disco-interacting protein 2 homolog B 1 GT(0.002)S(0.093)GS(0.905)LADVFANTR 98.676 0.0023945 3904000.0 9039.1 9681.2 14298.0 15474.0 15430.0 15108.0 12476.0 13835.0 13066.0 13107.0 True False 11913.345775040165 12810.458573815531 14108.399177852756 11906.708370916813 13287.810841187327 14163.294371682376 13586.3398307855 11697.118646672523 13756.642085232319 12648.12791946031 0.9419058576020871 1.0128343621592772 1.1154535491490154 0.9413810839624135 1.050575304566837 1.1197937324693594 1.0741779271445906 0.9248102739912544 1.0876425485914367 1.0 13.62663624342714 -4.825412220589807 4.076062516023547 1.038978428545713 0.937783861958834 0.1744474893193485 0.06349645379489811 0.3715368279788459 10.809963292026673 0.015869775939220503 0.09797796393694425 1.4948161434184188e-05 4.825412220589807 -0.10119456658687909 GTSGS(ph)LADVFANTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GTSGSLADVFANTR 14 0 Q9P265 Q9P265 DIP2B Disco-interacting protein 2 homolog B 1 GT(0.001)S(0.006)GS(0.993)LADVFANTR;GT(0.001)S(0.051)GS(0.949)LADVFANTR 111.81 0.00036425 7386900.0 23556.0 20678.9 24972.0 32186.0 37103.0 28688.0 26603.0 24103.0 24480.0 21232.4 True False 27543.56554779266 22731.764529910917 25567.427186837383 30382.722768419895 29832.93349611408 27183.550777662324 24082.97125095903 23470.321789239486 24837.97368839003 25081.66604441408 1.0981553417950427 0.9063099911169374 1.0193671800574622 1.211351858150843 1.1894318919359885 1.0838016393937417 0.9601822784943161 0.9357560916279939 0.9902840443058079 1.0 14.614345561588253 -7.259369769851238 22.7155502077102 0.9662019333611986 1.0841688591412304 0.3170601755842478 0.08122195310423208 71.79042734268388 787972.8862253954 0.03664747144764281 0.02691476944877553 5.5033892370130806e-08 7.259369769851238 0.11796692578003176 GTSS(ph)PDYR ddPTM_PC-9_AZD4547_30min_R2 1 GTSSPDYR 8 0 Q66K14;Q66K14-2;G3V133 Q66K14 TBC1D9B TBC1 domain family member 9B 1 GT(0.001)S(0.227)S(0.771)PDYR 138.06 0.0030598 79248000.0 110330.0 96867.0 147880.0 158540.0 136660.0 121730.0 109110.0 149270.0 107300.0 111040.0 True False 145412.64499343728 128177.36341257162 145919.01457692432 121991.0524185828 117687.11792330931 114118.2038565589 118820.57862592228 126203.75138336167 112971.65894270834 107152.5233979455 1.3570622546461222 1.196214138014684 1.3617879444145888 1.1384804440445107 1.0983140125057083 1.06500715277366 1.108892024732294 1.1777954207822365 1.0543070322586021 1.0 16.709306299727388 -5.89089484440422 5.29158297891334 1.0953520671197534 1.293058147560107 0.7217505667299602 0.06098824423069693 0.11208607049279516 4.782036212869981 0.01652590953886151 0.024943430190115076 1.2855979037055295e-06 5.89089484440422 0.19770608044035365 GTSS(ph)PDYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GTSSPDYR 8 0 Q66K14;Q66K14-2;G3V133 Q66K14 TBC1D9B TBC1 domain family member 9B 1 GT(0.037)S(0.118)S(0.846)PDYR;GT(0.048)S(0.313)S(0.634)PDY(0.005)R 113.66 0.0037104 118089000.0 114585.0 123584.0 144388.0 139584.0 139120.0 114305.0 141682.0 116333.0 116137.0 98802.0 True False 133981.97734308973 135852.6027817973 147830.75751453935 131763.56101743394 111860.4346812761 108310.64457754788 128260.85527114887 113279.38201500205 117835.28391538188 116714.02048379809 1.1479510069802517 1.163978433941927 1.2666066758882735 1.1289437247663403 0.9584147150239268 0.928000287613974 1.0989327138203904 0.9705721861473119 1.0096069300580683 1.0 16.832618352255665 -6.102481454107392 4.366443264621717 0.9955042612493933 1.1912726063862635 0.7593753232249213 0.05117799848916141 0.11152836469541969 3.5793467772513923 0.015659285872006892 0.020818885840480243 7.898025760107902e-07 6.102481454107392 0.19576834513687025 GTT(ph)PPPPSWEPNSQTK ddPTM_PC-9_AZD4547_30min_R2 1 GTTPPPPSWEPNSQTK 16 0 O95835;O95835-2 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 GT(0.16)T(0.84)PPPPSWEPNSQTK 97.20299999999999 0.0092564 0.0 8456.9 11932.0 15271.0 15404.0 15720.0 12565.0 15790.0 12410.0 12777.0 15677.0 True False 11146.018285552449 15788.785657022572 15068.496562105849 11852.845789427589 13537.549346951691 11779.308563687395 17195.279410716823 10492.319653430139 13452.366135237513 15128.15300170742 0.736773238894032 1.0436690887010853 0.9960565946421326 0.7834958959028133 0.8948580401998706 0.7786349438928822 1.136641030056749 0.6935625024578966 0.8892272661255626 1.0 13.884948239018529 -5.789880910438415 0.003970672408811634 1.7799518033628625 1.3302288828133803e-07 0.015620379664787243 0.13795991609351788 390495.0902880439 351.40009897498123 77217.95912920618 80316.20197041766 1.6222548811286072e-06 5.789880910438415 -1.7799516703399743 GTTATSAQANSTPTSVASVVTSAES(ph)PASR ddPTM_PC-9_AZD4547_30min_R2 2 GTTATSAQANSTPTSVASVVTSAESPASR 29 0 Q86YP4-2;Q86YP4;Q86YP4-3 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 1 GTTATSAQANSTPTSVASVVTS(0.003)AES(0.949)PAS(0.047)R;GTTATSAQANSTPTSVASVVT(0.003)S(0.027)AES(0.79)PAS(0.181)R 153.66 5.1405e-12 13750200.0 52228.0 41134.0 65683.0 100432.0 82840.0 69844.0 60427.0 86379.0 61554.0 75187.0 True False 68835.41759011381 54429.76108078835 64812.00050349015 77278.95405893224 71339.09592248591 65476.64363885246 65804.88593738973 73031.11034195361 64807.61877501839 72554.72601514179 0.9487378889108922 0.7501890513573043 0.8932843394648644 1.065112616410467 0.9832453354947246 0.9024449162028099 0.9069689812302041 1.0065658621150662 0.8932239474172003 1.0 16.146781970086046 -5.52832096865631 24.994187438791233 0.9627041252781152 0.8425317653669746 0.33220068425027827 0.06752500706238067 141.9749361195412 652038.3984997899 0.017928942443549693 0.031179730151982308 2.9626410177299165e-06 5.52832096865631 -0.12017235991114061 GTTATSAQANSTPTSVASVVTSAES(ph)PASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GTTATSAQANSTPTSVASVVTSAESPASR 29 0 Q86YP4-2;Q86YP4;Q86YP4-3 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 1 GTTATSAQANSTPTSVASVVT(0.013)S(0.108)AES(0.653)PAS(0.225)R 107.05 1.6884e-05 0.0 6761.8 7806.9 13220.0 10003.0 15708.0 11099.0 8995.8 13313.0 10409.0 9593.2 True False 7906.439188362388 8581.917437995322 13535.214937129194 9442.564340163555 12630.130160821494 10516.948901327174 8143.652700048012 12963.547856289484 10561.211933106688 11332.371220270586 0.6976862154162299 0.7572922975418034 1.194385065053138 0.8332381773086756 1.1145178635014676 0.9280448634188015 0.7186185963870643 1.1439395696022698 0.9319507566267772 1.0 13.468162146250283 -5.058443087213775 11.782219807599816 0.976207877067752 0.7125209518243774 0.36147580122578804 0.13664637915856004 1.0094090727310279 202.7809502099035 0.03347323087022901 0.08884108238816578 8.740915317503472e-06 5.058443087213775 -0.26368692524337467 GTTATSAQANSTPTSVASVVTSAES(ph)PASR ddPTM_PC-9_Lapatinib_30min_R1 2 GTTATSAQANSTPTSVASVVTSAESPASR 29 0 Q86YP4-2;Q86YP4;Q86YP4-3 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 1 GTTATSAQANSTPTSVASVVT(0.001)S(0.001)AES(0.967)PAS(0.031)R;GTTATSAQANSTPTSVASVVT(0.01)S(0.066)AES(0.732)PAS(0.192)R 183.17 2.9596999999999995e-25 12926100.0 104612.0 98972.0 115878.0 98778.0 112121.0 104485.0 83353.0 83709.0 110374.0 80143.0 True False 103120.21369650867 98742.83641482178 106350.9581420153 106042.46363374827 105526.26321836728 100016.42011643127 87668.61049063878 87598.42573472855 97942.51783025345 93995.61076616497 1.0970747767472162 1.050504758785669 1.1314460034371925 1.1281639937161803 1.1226722435038736 1.0640541542439084 0.9326883433816285 0.931941662176643 1.0419903337178933 1.0 16.52030576959789 -7.084664611215997 4.434928935003441 0.9718104585350915 1.104822738987435 0.7325483352281863 0.036824376138053214 0.11858439457165058 4.1568866380638845 0.01490565979161596 0.011575850468582035 8.228778813051527e-08 7.084664611215997 0.13301228045234348 GTVMQAPAVRQVNPQNS(ph)KRFFLYMAPR ddPTM_PC-9_AZD4547_30min_R2 1 GTVMQAPAVRQVNPQNSKRFFLYMAPR 27 3 Q6VMQ6-2 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 GTVMQAPAVRQVNPQNS(0.953)KRFFLY(0.047)MAPR 48.641000000000005 0.0097488 63209000.0 26115.0 9726.1 22910.0 34752.0 29379.0 27377.0 25022.0 25183.0 23797.0 27812.0 True False 34419.02677425562 12869.871620748178 22606.19843087191 26740.46331304777 25300.23296845382 25665.111862162328 27248.909525963023 21291.54599777046 25054.860837461638 26838.310345313963 1.2824587811752937 0.47953360160004593 0.8423107915517122 0.996354202965565 0.9426909758076967 0.9562864253353983 1.0152989951813696 0.7933266186963226 0.9335483685483308 1.0 14.712006226453854 -5.671234847797844 7.622764690877503 0.9423132057335257 0.8274927973491892 0.022718495178020714 0.19031579878171664 0.6818747909941985 49.77583462848983 0.049146969259970294 0.0853278494587087 2.131891765910832e-06 5.671234847797844 -0.11482040838433649 GTVPDDAVEALADS(ph)LGKK ddPTM_PC-9_AZD4547_30min_R2 2 GTVPDDAVEALADSLGKK 18 1 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;P20810-2;E9PCH5;P20810-3;H0Y7F0;H0Y9H6;E7EQ12;E7EQA0;H0YD33;A0A0A0MR45 P20810-6 CAST Calpastatin 1 GTVPDDAVEALADS(1)LGKK;GTVPDDAVEALADS(1)LGKK 129.06 1.9329e-05 8514800.0 26434.0 24026.0 28266.0 31799.0 34575.0 25401.0 22235.6 28190.0 27358.0 29253.0 True False 34839.46213864341 31791.934645962483 27891.174371323676 24468.231839652566 29774.858057942416 23812.671454534284 24214.52532393509 23833.883241756314 28804.088027536025 28228.861373920223 1.2341787958486528 1.1262209348384868 0.988037526624842 0.8667806864593559 1.054766526483087 0.8435576319962406 0.8577931997748285 0.8443090539874097 1.0203772531238982 1.0 14.784883317641778 -5.135931374713495 1.6903890946200724 0.9175642761917882 1.2546183260738946 0.6573795748430438 0.07365129743305947 0.30263302066187486 1.3443300812779315 0.021063763960910115 0.13237604332752198 7.3125462396473775e-06 5.135931374713495 0.3370540498821064 GTVPDDAVEALADS(ph)LGKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GTVPDDAVEALADSLGKK 18 1 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;P20810-2;E9PCH5;P20810-3;H0Y7F0;H0Y9H6;E7EQ12;E7EQA0;H0YD33;A0A0A0MR45 P20810-6 CAST Calpastatin 1 GTVPDDAVEALADS(1)LGKK;GTVPDDAVEALADS(1)LGKK 81.89 0.0013384 6444100.0 32839.0 31567.0 23383.0 39409.0 35209.0 32427.0 34418.0 30039.0 29655.0 29726.0 True False 38397.99410018523 34700.76314096484 23940.539400521327 37201.04149570188 28310.049199921305 30726.471035529004 31157.677875258705 29250.50807895139 30088.64827325189 35115.088489113485 1.0934898857535136 0.9882009311103659 0.6817735745687631 1.059403324791139 0.8062075426265292 0.8750218882420001 0.8873017046480839 0.8329897299851527 0.8568581076644614 1.0 15.099803450279248 -5.00775779436486 22.110204287926003 0.870985533008894 1.0671682417321018 0.33974657043090273 0.0973457518171824 76.68438578116334 218583.0987805879 0.022483243073715693 0.07371917712465086 9.822956156534897e-06 5.00775779436486 0.19618270872320775 GTVPDDAVEALADS(ph)LGKK ddPTM_PC-9_Lapatinib_30min_R1 2 GTVPDDAVEALADSLGKK 18 1 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;P20810-2;E9PCH5;P20810-3;H0Y7F0;H0Y9H6;E7EQ12;E7EQA0;H0YD33;A0A0A0MR45 P20810-6 CAST Calpastatin 1 GTVPDDAVEALADS(1)LGKK;GTVPDDAVEALADS(1)LGKK 160.95 2.2378e-06 7436100.0 36451.0 29305.0 25923.0 26604.0 32209.0 30370.0 25187.0 30164.0 28211.0 30570.0 True False 35931.202055705275 29237.146072993834 23791.71100567379 28560.546908342356 30314.529945330414 29071.145895927813 26491.05961906252 31565.529559095863 25033.580105000066 35853.98376803544 1.002153687806895 0.8154504186243133 0.6635723148534638 0.7965794566405943 0.8454996281990967 0.8108205237111011 0.7388595864395923 0.8803911376575447 0.6982091660151309 1.0 15.129845806512325 -11.059671741856597 4.993214329092129 1.0009579198295495 0.8031112007637886 0.2919162375764932 0.0906890512867073 0.0009572985051774386 8.88060247994802e-05 0.0869204383531357 0.02098178494577492 8.716221499381902e-12 11.059671741856597 -0.1978467190657609 GTVTDFPGFDER ddPTM_PC-9_AZD4547_30min_R2 1 GTVTDFPGFDER 12 0 D6RBE9;P08758;D6RCN3;E9PHT9 D6RBE9 ANXA5 Annexin;Annexin A5 0 105.17 0.0084018 17421000.0 67834.0 66406.0 109480.0 139490.0 110060.0 112240.0 76595.0 110410.0 82529.0 97444.0 False True 89403.80096514845 87870.44085989271 108028.22366703875 107332.73559901696 94780.06877388699 105221.61505676655 83411.80661582366 93348.67146939755 86891.31445370731 94032.51521964527 0.9507753861131454 0.9344686851632235 1.148839030995839 1.1414427801734799 1.0079499474463227 1.118991816936783 0.8870528074356696 0.99272758206403 0.9240560485991762 1.0 16.52087208777425 -7.262764814730654 24.996752249127017 0.9503530766044112 1.0518228802986993 0.29454319660034156 0.07538026574269927 168.10651752929965 3170334.1146003227 0.03218490039791959 0.02306394894212463 5.460534876195206e-08 7.262764814730654 0.10146980369428815 GTVTDFPGFDER ddPTM_PC-9_Lapatinib_30min_R1 2 GTVTDFPGFDER 12 0 D6RBE9;P08758;D6RCN3;E9PHT9 D6RBE9 ANXA5 Annexin;Annexin A5 0 ; 133.89 0.00025686 31792900.0 51443.0 43936.0 59762.0 41698.0 45973.0 49500.0 44695.0 38968.0 44655.0 40034.0 False True 50709.41338650917 43834.26889141978 54848.599047991185 44764.61002045029 43268.958526395574 47383.00039013589 47009.088405685434 40778.59553967805 39625.483662003404 46953.823558048134 1.079984749779069 0.9335612218508317 1.168139139514014 0.9533751807264138 0.9215215130010226 1.0091404021987085 1.0011770042022026 0.8684829572881159 0.8439245339203347 1.0 15.518955024193758 -6.594423752945549 0.7143926144537275 0.9118945362494446 1.0460877111579765 0.26064695143767047 0.07894111790735589 1.0180854655787168 1.1571473303963757 0.05525496475425945 0.0668798612362517 2.544346452946757e-07 6.594423752945549 0.1341931749085319 GTWNGPWVSTEVLAAAIGLVIYYLAFS(ph)AK ddPTM_PC-9_AZD4547_30min_R2 1 GTWNGPWVSTEVLAAAIGLVIYYLAFSAK 29 0 A6NLM8;P51571 A6NLM8 SSR4 Translocon-associated protein subunit delta 1 GTWNGPWVSTEVLAAAIGLVIY(0.157)Y(0.157)LAFS(0.685)AK 44.3 0.016958 7404800.0 32213.0 39024.0 32122.0 27034.0 36620.0 38051.0 29867.0 29903.0 28850.0 31430.0 True False 42456.06392797609 51637.74484408724 31696.041291858044 20801.728971136432 31535.94510721189 35671.66495478461 32525.10513995438 25282.178452580294 30374.952101557676 30329.645266547454 1.3998206558255943 1.702550240541121 1.0450515003819605 0.6858546741422004 1.039772962395803 1.176131954109243 1.0723865991215018 0.8335797610025351 1.0014938135481655 1.0 14.888441003947879 -5.3294054161897035 6.126977517884538 0.9745604292763653 1.5492885432163308 0.7145545502805775 0.1441716079943723 0.10747147519437743 7.5661153282012314 0.03919360226413042 0.08360848609976648 4.683759465860703e-06 5.3294054161897035 0.5747281139399655 GTYFPAILNPPPS(ph)PATER ddPTM_PC-9_AZD4547_30min_R2 1 GTYFPAILNPPPSPATER 18 0 H0YGW5;F5H7J9;O75581 H0YGW5 LRP6 Low-density lipoprotein receptor-related protein 6 1 GTYFPAILNPPPS(0.682)PAT(0.318)ER 101.53 0.0005199 3601100.0 13424.0 24410.0 29594.0 32215.0 32571.0 22830.0 26130.0 40026.0 23821.0 26852.0 True False 17692.552763454238 32300.055136433202 29201.5642236239 24788.32946678849 28049.078866384476 21402.436490965614 28455.519379482612 33840.90140597865 25080.12942846466 25911.919653112698 0.682795910156695 1.2465326988057839 1.1269548769273074 0.9566380954647166 1.0824778419307521 0.8259687733476984 1.0981633070965608 1.3059974659929712 0.9678993206299126 1.0 14.6613282793375 -7.499327137197598 24.843403305700633 1.1225851341813575 1.0042016731572114 0.07152824030170124 0.17024854129176148 1713.355666331163 1807339.2371883544 0.06978715511508264 0.04670525728111301 3.1671808497277716e-08 7.499327137197598 -0.1183834610241461 GTYVPSS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 3 GTYVPSSPTR 10 0 Q9Y4P8-4;Q9Y4P8 Q9Y4P8-4 WIPI2 WD repeat domain phosphoinositide-interacting protein 2 1 GTYVPS(0.024)S(0.969)PT(0.007)R;GTYVPS(0.007)S(0.991)PT(0.002)R;GTYVPS(0.168)S(0.769)PT(0.063)R 104.07 0.0026576 600161000.0 388275.0 350261.0 478929.0 671562.0 523585.0 416394.0 388165.0 537362.0 362099.0 387353.0 True False 511738.37337829254 463476.01852282725 472578.0885333501 516743.7564294709 450894.2604849679 390356.8173551969 422710.93302475516 454325.05025032465 381238.81390024006 373791.8893710766 1.3690462204498812 1.2399306451048167 1.264281280496712 1.3824370488587057 1.2062708509904265 1.0443159106849311 1.130872405326898 1.215449192904504 1.0199226487810993 1.0 18.511875739905456 -6.533361261693553 5.07129391517463 1.0998303002943386 1.3047399802655202 0.7021782468144948 0.07066809262879445 0.11075276367504101 8.290949145268497 0.023020454729504092 0.023985169508646906 2.9284562370873627e-07 6.533361261693553 0.2049096799711816 GTYVPSS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 GTYVPSSPTR 10 0 Q9Y4P8-4;Q9Y4P8 Q9Y4P8-4 WIPI2 WD repeat domain phosphoinositide-interacting protein 2 1 GTYVPS(0.003)S(0.958)PT(0.039)R;GTYVPS(0.006)S(0.936)PT(0.059)R;GTYVPS(0.003)S(0.983)PT(0.014)R;GTYVPS(0.003)S(0.964)PT(0.033)R;GTYVPS(0.002)S(0.997)PT(0.001)R;GTYVPS(0.046)S(0.894)PT(0.06)R 155.26 0.00011382 563479000.0 998339.0 937714.0 1043069.0 1108676.0 1293156.0 1197679.0 1284367.0 1119314.0 1187615.0 968300.0 True False 1167338.0746059506 1030804.0487840673 1067939.7208212127 1046560.4780960876 1039771.3647980212 1134870.6048466193 1162702.4597481664 1089933.193511217 1204981.6226281608 1143845.1249414154 1.0205385756797614 0.9011744914652342 0.9336401384548539 0.9149494588698707 0.9090141157451499 0.9921540775939787 1.0164859161398418 0.9528678050422607 1.05344823031866 1.0 20.12546029573693 -6.849675153993711 6.258330534253345 1.0018774798199128 0.9328063253346899 0.4306788541757195 0.038598335333212476 0.2020839223812659 11.647598924674183 0.013168561536896415 0.01164208778814443 1.4135944975689742e-07 6.849675153993711 -0.06907115448522294 GTYVPSS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 4 GTYVPSSPTR 10 0 Q9Y4P8-4;Q9Y4P8 Q9Y4P8-4 WIPI2 WD repeat domain phosphoinositide-interacting protein 2 1 GTYVPS(0.003)S(0.884)PT(0.114)R;GTYVPS(0.002)S(0.997)PTR;GTYVPS(0.033)S(0.909)PT(0.058)R;GTYVPS(0.038)S(0.926)PT(0.036)R 158.06 0.00026489 561358000.0 1902630.0 1598550.0 1608550.0 1281288.0 1615700.0 1737150.0 1682280.0 1691960.0 1920280.0 1312931.0 True False 1875498.1473003936 1594848.6556896223 1476301.2281825652 1375518.1937714678 1520667.7025884178 1662856.1439944343 1769380.2269407406 1770574.6384036539 1703997.8449551417 1539869.373979412 1.2179592496561134 1.0357038607554938 0.9587184816640838 0.8932694012978392 0.9875303245096874 1.0798683135681784 1.1490456637683588 1.1498213214202975 1.1065859700499012 1.0 20.554376542643652 -6.918471998926122 4.712849211195489 1.1140356975671166 1.009798709886428 0.16076590376152755 0.08737382866745544 0.3352011055032646 13.507806707201455 0.03347306511547396 0.029253030675488137 1.206501874723129e-07 6.918471998926122 -0.10423698768068856 GVAPADS(ph)PEAPR ddPTM_PC-9_AZD4547_30min_R2 2 GVAPADSPEAPR 12 0 Q9P2G1 Q9P2G1 ANKIB1 Ankyrin repeat and IBR domain-containing protein 1 1 GVAPADS(1)PEAPR;GVAPADS(1)PEAPR 107.09 0.001593 8657800.0 33917.0 33467.0 37691.0 66491.0 47191.0 43121.0 37542.0 45901.0 29509.0 40336.0 True False 44701.90048257428 44284.55326714502 37191.19271313809 51162.52722570953 40639.34422595404 40424.63705330392 40883.16527150927 38808.05515004812 31068.785496182514 38923.84891732287 1.148445020879729 1.1377228742514307 0.9554860001675303 1.314426210377666 1.044073116003379 1.0385570332257952 1.0503371688228502 0.9970251203183759 0.7981940727951881 1.0 15.248366755120305 -7.550024720129209 1.1657145987005502 0.90815554753272 1.1187391263528497 0.39824178842800506 0.09967305145054779 0.5041048313923202 1.2735877213241222 0.07655723431121919 0.03460026179039103 2.8182225129070377e-08 7.550024720129209 0.21058357882012968 GVAPADS(ph)PEAPR ddPTM_PC-9_Lapatinib_30min_R1 3 GVAPADSPEAPR 12 0 Q9P2G1 Q9P2G1 ANKIB1 Ankyrin repeat and IBR domain-containing protein 1 1 GVAPADS(1)PEAPR;GVAPADS(1)PEAPR;GVAPADS(1)PEAPR 130.56 0.00014222 15648400.0 50144.0 65883.0 72228.0 56711.0 52936.0 64860.0 51347.0 53294.0 68952.0 55992.0 True False 49428.93736471661 65730.4519613396 66289.69264814285 60881.71612235014 49822.40855618031 62086.08899604471 54005.496417199465 55770.23379931226 61185.89966325064 65670.14259534977 0.7526850926651828 1.0009183681290514 1.0094342729939032 0.9270836595786727 0.7586767225888181 0.9454233924633072 0.8223751964416124 0.8492479473199965 0.9317156510572787 1.0 16.00294996744335 -4.7368717628049675 24.572106933165816 0.9077145785770955 0.7526842315646572 0.2713513708318219 0.07926982942646935 2831.0660993623874 2831401.447379992 0.020625653039281266 1.3327560157658358 1.8328555426614794e-05 4.7368717628049675 -0.15503034701243823 GVAPADS(ph)PEAPRR ddPTM_PC-9_AZD4547_30min_R2 4 GVAPADSPEAPRR 13 1 Q9P2G1 Q9P2G1 ANKIB1 Ankyrin repeat and IBR domain-containing protein 1 1 GVAPADS(1)PEAPRR;GVAPADS(1)PEAPRR;GVAPADS(1)PEAPRR;GVAPADS(1)PEAPRR 118.24 0.00036189 30590300.0 78297.0 60881.2 120178.0 165974.0 133019.0 105233.0 106237.0 140884.0 97934.0 123348.0 True False 103193.81732122862 80559.85730324521 118584.36119708986 127711.25857273802 114551.60792507445 98652.7638744542 115691.88719166072 119113.61499225219 103110.59130377628 119029.62406420936 0.8669591131831327 0.6768051057591175 0.9962592264688721 1.0729367548354638 0.9623789777180235 0.8288084974647735 0.9719587716184995 1.00070563045715 0.8662599089463164 1.0 16.860961150253324 -5.272974227861861 24.95058727690394 0.9619540023492272 0.7718821064712604 0.48567586812154184 0.07842694295194515 529.9256818405009 1146262.6795422111 0.020862177779323313 0.04402808911639669 5.333665458746704e-06 5.272974227861861 -0.1900718958779668 GVAPADS(ph)PEAPRR ddPTM_PC-9_Lapatinib_30min_R1 4 GVAPADSPEAPRR 13 1 Q9P2G1 Q9P2G1 ANKIB1 Ankyrin repeat and IBR domain-containing protein 1 1 GVAPADS(1)PEAPRR;GVAPADS(1)PEAPRR;GVAPADS(1)PEAPRR;GVAPADS(1)PEAPRR 132.97 7.297300000000001e-05 39494200.0 102728.0 99402.0 113825.0 91810.0 99631.0 93915.0 77174.0 86374.0 125849.0 78759.0 True False 101263.07988199186 99171.84077624088 104466.7478772064 98562.01366918164 93770.90046208244 89898.47437655777 81169.69210471783 90387.25136378956 111674.56037127909 92372.38821022896 1.096248368630772 1.07360914552233 1.1309304641929585 1.0670073122377848 1.0151399382320896 0.9732180375369224 0.8787224589233843 0.9785094129869041 1.208960410519219 1.0 16.495174047799637 -6.200136885430365 2.962669088678425 0.9984668055809747 1.097596270200079 0.21265616172143065 0.07849596921288061 0.41177718161640664 7.148560245892998 0.025967688766984284 0.033898619253446956 6.307585041509866e-07 6.200136885430365 0.09912946461910432 GVDEATIIDILTK ddPTM_PC-9_Lapatinib_30min_R1 2 GVDEATIIDILTK 13 0 P04083;Q5T3N0;Q5T3N1 P04083;Q5T3N1 ANXA1 Annexin A1;Annexin 0 ; 262.07 2.6541e-44 320860000.0 1540900.0 1334600.0 1666770.0 1327990.0 1377730.0 1422400.0 1570670.0 1352510.0 1416020.0 1418600.0 False True 1518926.4834335446 1331509.8156975782 1529734.6045182613 1425654.814644773 1296694.6301213985 1361567.26777635 1651991.6072526672 1415352.5521805077 1256532.916248349 1663803.1198343218 0.912924411143547 0.8002808744764028 0.9194204448123581 0.8568650927801703 0.7793558111914832 0.8183463845842123 0.9929008952797067 0.8506730966590841 0.7552173098301872 1.0 20.66605329676753 GVDEVTIVNILTNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GVDEVTIVNILTNR 14 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9 P07355 ANXA2 Annexin A2;Annexin 0 91.12299999999999 0.021483000000000002 25462000.0 9397.0 12676.0 12261.0 11642.0 11621.0 8916.3 10552.0 14971.0 10342.0 8513.1 False True 10987.72650078993 13934.38950723446 12553.348740101439 10989.736483873254 9343.948472046513 8448.713531750924 9552.43817013568 14578.02711308569 10493.232184858236 10056.457640337474 1.092604065343749 1.3856160892422207 1.248287338252058 1.0928039352338446 0.9291490906864646 0.840128187669411 0.9498810129542911 1.449618507277527 1.0434322462383587 1.0 13.295834588798238 -5.820367609777582 4.164033759879525 1.041720292559436 1.2582592773762737 0.2353459201016712 0.16551396885845968 0.3281777488501955 11.449800182515556 0.051320478235301274 0.08129856264731325 1.512280632355722e-06 5.820367609777582 0.21653898481683775 GVDEVTIVNILTNR ddPTM_PC-9_Lapatinib_30min_R1 2 GVDEVTIVNILTNR 14 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9 P07355 ANXA2 Annexin A2;Annexin 0 ; 202.61 3.1292e-08 110136000.0 199623.0 155776.0 176146.0 176935.0 191355.0 189344.0 181549.0 161854.0 173140.0 168984.0 False True 196776.3394136255 155415.3102428488 161663.95582322334 189947.39013785697 180099.8751184049 181246.19850242208 190948.71889392065 169374.327717077 153639.14995497183 198192.65924297346 0.992853822968228 0.7841627981403592 0.8156909364893888 0.9583977068746616 0.9087111288900575 0.9144950130580974 0.9634500067927737 0.8545943546245739 0.77520101169145 1.0 17.596544002703475 -4.693342853414828 22.84618568575045 0.8856077790071386 0.9928672145747143 0.15929684599464167 0.07358161539040721 40294.085710624655 13512384.59099556 0.01862619816130326 101.51151172072727 2.026082598787512e-05 4.693342853414828 0.10725943556757567 GVDLLLEGVQGES(ph)SPTRR ddPTM_PC-9_AZD4547_30min_R2 2 GVDLLLEGVQGESSPTRR 18 1 F5H7T0;F6RJM5;Q96S38-2;Q96S38 F5H7T0 RPS6KC1 Ribosomal protein S6 kinase delta-1 1 GVDLLLEGVQGES(0.5)S(0.5)PT(0.001)RR;GVDLLLEGVQGES(0.746)S(0.123)PT(0.131)RR 104.42 0.00016796 5021300.0 15653.9 20309.4 23226.4 27227.6 28390.0 25902.4 24322.3 22333.7 22125.0 24656.3 True False 20631.51457865288 26874.016378036707 22918.402760139827 20950.697482226613 24448.538547071177 24282.718833271494 26486.937581461538 18882.53984237009 23294.482330917268 23793.090441793625 0.8671221012303936 1.1294882623079219 0.9632377440083457 0.8805370421921223 1.0275478339764652 1.0205785958186337 1.1132197242833175 0.7936144272037089 0.9790439954785979 1.0 14.538255052551664 -7.757828317048183 24.999982164723537 0.9147469297410286 1.0010224210103194 0.11633339000253651 0.09493512462196356 177.1534956387821 1226490.4604298589 0.045437999794208095 0.024904096187645317 1.7465124383472552e-08 7.757828317048183 0.0862754912692908 GVDLLLEGVQGES(ph)SPTRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GVDLLLEGVQGESSPTRR 18 1 F5H7T0;F6RJM5;Q96S38-2;Q96S38 F5H7T0 RPS6KC1 Ribosomal protein S6 kinase delta-1 1 GVDLLLEGVQGES(0.587)S(0.38)PT(0.033)RR;GVDLLLEGVQGES(0.586)S(0.404)PT(0.011)RR 86.83200000000001 0.00078097 4467400.0 19137.0 16471.4 23239.3 24919.3 24659.9 21776.1 21903.2 19505.1 18859.2 19062.0 True False 22376.51612702106 18106.571736309706 23793.41304753603 23523.15241046064 19827.969617573344 20634.122981366843 19828.370330564427 18993.111792361746 19134.9801218989 22517.789705291027 0.9937261347530583 0.8041007564812273 1.0566495805734106 1.0446474862021373 0.8805468865762766 0.916347618990261 0.8805646819725532 0.8434714082039285 0.8497716859573805 1.0 14.458777602273447 -6.306154856707899 24.788047550306757 0.8876245002866193 0.968437356207721 0.20209241983160953 0.0762698899774452 668.9810153092874 370848.2603722355 0.02419875683256548 0.027438949606526816 4.94134461676111e-07 6.306154856707899 0.08081285592110166 GVDLLLEGVQGES(ph)SPTRR ddPTM_PC-9_Lapatinib_30min_R1 2 GVDLLLEGVQGESSPTRR 18 1 F5H7T0;F6RJM5;Q96S38-2;Q96S38 F5H7T0 RPS6KC1 Ribosomal protein S6 kinase delta-1 1 GVDLLLEGVQGES(0.448)S(0.448)PT(0.103)RR;GVDLLLEGVQGES(0.533)S(0.466)PT(0.001)RR 91.565 0.00056173 6423800.0 20733.7 21387.0 25206.5 19950.3 22142.7 21648.2 19138.2 18612.7 23763.8 15983.3 True False 20438.033635905093 21337.479715513353 23134.1188699038 21417.511614249845 20840.309920223175 20722.356950418976 20129.082352068202 19477.51399100198 21087.270600092193 18745.992108591472 1.0902615085673775 1.1382422222259538 1.234083463595464 1.1425115027352428 1.1117208307514361 1.105428660717387 1.0737805838957355 1.0390228416918645 1.1248948830202319 1.0 14.194294560057774 -6.826759582713066 1.3190647485787497 1.060657395438894 1.1549969988753745 0.4551087337657288 0.044398075856449774 0.4150637231374567 1.5084085453904592 0.02245517204491731 0.019102132914552934 1.4901857883455017e-07 6.826759582713066 0.09433960343648051 GVDLLLEGVQGESS(ph)PTRR ddPTM_PC-9_AZD4547_30min_R2 1 GVDLLLEGVQGESSPTRR 18 1 F5H7T0;F6RJM5;Q96S38-2;Q96S38 F5H7T0 RPS6KC1 Ribosomal protein S6 kinase delta-1 1 GVDLLLEGVQGES(0.343)S(0.477)PT(0.18)RR 67.563 0.0058912 1353300.0 7730.8 7146.5 10112.0 13723.0 11302.0 7835.5 7605.2 9357.8 6660.2 8870.3 True False 10189.033589370672 9456.466367575578 9977.90827293657 10559.374368236484 9732.91238672062 7345.544946340829 8282.048066775396 7911.767030851616 7012.244574932212 8559.753496909192 1.1903419406937117 1.104759193239639 1.1656770579362423 1.2336072962906381 1.1370552189657144 0.8581491218167909 0.9675568425850031 0.9242984665047241 0.8192110412366707 1.0 13.0633535352713 -6.701828348332078 6.169295827352297 0.9126874017214455 1.1689874782675942 0.8337864082720728 0.056424918186250915 0.07752473969856107 5.8336676107495675 0.018579801912193238 0.018397706564313995 1.986880061771266e-07 6.701828348332078 0.2563000765461487 GVDLLLEGVQGESS(ph)PTRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GVDLLLEGVQGESSPTRR 18 1 F5H7T0;F6RJM5;Q96S38-2;Q96S38 F5H7T0 RPS6KC1 Ribosomal protein S6 kinase delta-1 1 GVDLLLEGVQGES(0.083)S(0.831)PT(0.086)RR 85.805 0.00082856 5014300.0 8529.1 9437.0 11218.0 8532.0 14516.0 10687.0 9089.3 12468.0 10905.0 10668.0 True False 9972.908172596293 10373.842993039732 11485.479664501914 8053.979701117219 11671.694003977902 10126.554906611718 8228.295703166628 12140.72821093797 11064.46499476687 12602.023952158457 0.7913735293994698 0.8231886427467799 0.9113996059763636 0.6391020784988862 0.926176148235204 0.8035657561877 0.6529344599251692 0.9633951067723946 0.8779911097432697 1.0 13.621367836389723 -7.805927747524283 24.999998443142783 0.9405201656898705 0.7979478807706278 0.37172830486396247 0.09179195717521564 157.40047070258672 88448.30404833886 0.04870505798249693 0.023397325578469293 1.5634077211987023e-08 7.805927747524283 -0.14257228491924268 GVDPNSRNS(ph)SR ddPTM_PC-9_AZD4547_30min_R2 1 GVDPNSRNSSR 11 1 Q9UK76;J3KT51;Q9UK76-2;F2Z3M5 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 GVDPNS(0.035)RNS(0.958)S(0.007)R 96.23 0.028432 7705000.0 10267.0 7430.7 11439.0 20445.0 25884.0 14466.0 11542.0 19862.0 13626.0 18104.0 True False 13531.69243313354 9832.528459741668 11287.311385890172 15731.721122101222 22290.45339036247 13561.438733171652 12569.215640183253 16792.784283354507 14346.242541969672 17470.184470428732 0.7745592186526844 0.5628176666585806 0.6460899943555761 0.900489697102503 1.2759140252979506 0.7762619081742783 0.7194666811594803 0.9612253557928457 0.8211843765160657 1.0 14.092607221528658 -5.77503625573099 6.877815710312477 0.9213986465456423 0.6505090978755279 0.3844326295468721 0.15122066786603666 0.15499013689435312 33.03076293666736 0.044369363087027464 0.06954857772374823 1.6786638742136293e-06 5.77503625573099 -0.2708895486701144 GVDPNSRNS(ph)SR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GVDPNSRNSSR 11 1 Q9UK76;J3KT51;Q9UK76-2;F2Z3M5 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 GVDPNS(0.001)RNS(0.96)S(0.039)R 95.18299999999999 0.030524000000000003 6575300.0 17072.0 8611.6 14563.0 13777.0 19312.0 16219.0 9916.9 20064.0 12814.0 9036.5 True False 19961.952412630173 9466.5027359183 14910.237150485049 13005.11935563664 15527.952232351974 15368.44708808231 8977.499439861505 19537.34125956525 13001.380508293701 10674.745917105362 1.8700166324935998 0.886812933013145 1.3967767726061449 1.218307157531221 1.4546437313762912 1.4397014418353224 0.8410035713801708 1.8302394653027145 1.2179569058838307 1.0 13.38191411042617 -8.53251296631405 23.690901057009345 0.9999999520233748 1.3468108363308815 0.1113735742071752 0.31845768838418137 1521.9002734423057 3742411.4912378476 0.28574286578140234 0.07377849052179651 2.934181899591823e-09 8.53251296631405 0.34681088430750673 GVDPNSRNS(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 1 GVDPNSRNSSR 11 1 Q9UK76;J3KT51;Q9UK76-2;F2Z3M5 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 GVDPNS(0.001)RNS(0.964)S(0.036)R 103.97 0.013226 7239900.0 40202.0 23977.0 27400.0 34211.0 20152.0 11452.0 12430.0 13851.0 26807.0 17627.0 True False 39628.712107856125 23921.482729642477 25147.27776705864 36726.99106455048 18966.69898035639 10962.224655915878 13073.5645795429 14494.568025561506 23787.713369775513 20673.803463498898 1.916856381933953 1.1570915227029992 1.2163837104990374 1.7764989944590819 0.9174266851207845 0.5302471156442249 0.6323734576767758 0.7011079529295478 1.150621046184097 1.0 14.335516212586624 -6.4108756603188075 5.683037314035265 0.7685965550958805 1.4661397093467126 0.6088696671252258 0.2718899404304314 0.1613663507008891 7.053760898790459 0.0854677779798213 0.09675083952271835 3.882615103967452e-07 6.4108756603188075 0.697543154250832 GVEEEEEDGEMRE ddPTM_PC-9_AZD4547_30min_R2 2 GVEEEEEDGEMRE 13 1 P62306 P62306 SNRPF Small nuclear ribonucleoprotein F 0 ; 110.93 0.0014620999999999998 25099000.0 12990.400000000001 11573.0 16763.0 28875.0 21737.7 18741.5 15604.2 21608.5 13819.2 16307.900000000001 False True 17121.07698289451 15313.745927650205 16540.711667250365 22218.3148643029 18719.795575014756 17569.591042287873 16992.943570659114 18269.402838931932 14549.654699544044 15736.965384738447 1.0879528908094542 0.9731066665814315 1.05107377838496 1.411855101737086 1.1895429085183746 1.1164535609468067 1.0798106976290804 1.160922858523246 0.9245527548566737 1.0 13.941869747175232 -8.259156786423915 24.931772496784532 0.9622763677029483 1.1344666059111663 0.2785117713156632 0.1104493175754359 264.22070331921185 2886062.0120724705 0.09081610334397032 0.030616375649610474 5.506088829596427e-09 8.259156786423915 0.172190238208218 GVEEEEEDGEMRE ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GVEEEEEDGEMRE 13 1 P62306 P62306 SNRPF Small nuclear ribonucleoprotein F 0 127.83 0.00026413 15349000.0 9194.9 10159.0 11472.0 10677.0 11962.0 12382.0 14060.0 10553.0 10377.0 7915.8 False True 10751.414962446883 11167.518381507965 11745.53598780227 10078.80230530104 9618.131969935492 11732.666122734758 12728.135014415064 10275.994931827749 10528.743993644734 9350.871878561675 1.1497767376212447 1.194275627614066 1.2560899283339273 1.0778462624868446 1.028581301812781 1.2547136005182271 1.3611709346158714 1.0989344165207804 1.1259638812700998 1.0 13.190885173323746 -8.568515247559327 1.830198276733756 1.0032072140663408 1.182177299863221 0.2597673845939188 0.09193600533969624 0.5991962591820572 4.506999920791829 0.09439297691859375 0.026715340066104997 2.7007522864806615e-09 8.568515247559327 0.17897008579688012 GVEEEEEDGEMRE ddPTM_PC-9_Lapatinib_30min_R1 4 GVEEEEEDGEMRE 13 1 P62306 P62306 SNRPF Small nuclear ribonucleoprotein F 0 ;;; 247.96 7.0425999999999996e-34 39697600.0 38044.0 39331.6 46225.0 38362.6 39498.4 45284.799999999996 33488.0 33254.3 46733.7 33885.2 False True 37501.485583584865 39240.530096726325 42424.5589336601 41183.91357788208 37175.181768842216 43348.07466802474 35221.84478195755 34799.41617879069 41470.058578321994 39742.211670809105 0.9436184854082978 0.9873766065603423 1.0674936585077168 1.0362763380914684 0.9354079757002455 1.0907313117620014 0.8862577924375611 0.875628575154288 1.0434763651762744 1.0 15.27838454095744 -7.275619824583962 24.98278960172097 0.9409764051708215 1.0095121728964582 0.15699083247804657 0.06500201040799612 1340.8395505912765 2362251.925258906 0.02686564711649676 0.01820012826296986 5.301273069853511e-08 7.275619824583962 0.06853576772563674 GVEFPMADLDALS(ph)PIHTPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GVEFPMADLDALSPIHTPQR 20 0 Q6ZVM7-2;Q6ZVM7-5;Q6ZVM7 Q6ZVM7-2 TOM1L2 TOM1-like protein 2 1 GVEFPMADLDALS(0.999)PIHT(0.001)PQR;GVEFPMADLDALS(0.999)PIHT(0.001)PQR;GVEFPMADLDALS(0.999)PIHT(0.001)PQR 86.791 0.00051733 5293000.0 32845.7 31304.7 31738.9 27002.4 35275.0 29961.2 34793.9 25649.0 32995.9 24036.1 True False 38405.82827785421 34412.42373044516 32495.675746448527 25489.543070961972 28363.116973706296 28389.981928321806 31497.969905978392 24975.740927361894 33478.40261539005 28393.65466033708 1.3526201095733927 1.2119758496082458 1.144469640670862 0.8977196974424062 0.9989244890453133 0.9998706495497247 1.1093313024609583 0.8796240295987804 1.1790804324374566 1.0 14.793280935586173 -5.23753627971711 1.883681395539997 1.0089011642288106 1.3361037453404967 0.6118801317396971 0.0879443957934892 0.2556857009544436 1.5822127820623462 0.02366663848700228 0.10494343564350132 5.787136422496816e-06 5.23753627971711 0.3272025811116861 GVEGLIDIENPNR ddPTM_PC-9_Lapatinib_30min_R1 2 GVEGLIDIENPNR 13 0 Q13442 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 0 ; 128.08 0.00050346 5326800.0 23683.0 24536.0 22998.0 24834.7 26018.0 26416.0 24570.7 21757.0 24373.0 21450.9 False True 23345.27607706972 24479.188399487346 21107.193214847255 26661.12668413058 24487.672393356104 25286.249258703618 25842.85062064155 22767.90964783349 21627.8560809318 25158.659483472413 0.9279220974553924 0.9729925561244058 0.8389633489301485 1.0597196842560388 0.973329775755457 1.00507140594335 1.027195055349376 0.9049730834343742 0.8596585241411563 1.0 14.618767433401441 -1.611400889431526 16.846627083847494 0.9581033751100624 0.004794219505607988 0.0 0.06865410445342045 0.0 0.0 0.01587915120056899 0.0 0.024468035986568454 1.611400889431526 -0.9533091556044544 GVEICIAT(ph)PGR ddPTM_PC-9_AZD4547_30min_R2 2 GVEICIATPGR 11 0 P17844-2;P17844;J3KTA4;J3QSF1;J3KRZ1;A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 P17844-2;A0A1X7SBZ2 DDX5;DDX17 Probable ATP-dependent RNA helicase DDX5;Probable ATP-dependent RNA helicase DDX17 1 GVEICIAT(1)PGR;GVEICIAT(1)PGR 101.56 0.0090098 14272200.0 31772.0 30667.0 52790.0 55662.0 47199.0 50405.0 41683.0 44551.0 35254.0 38743.0 True False 41874.83510134592 40579.508024129325 52089.97010762677 42829.985869327356 40646.233564044116 47253.167381827545 45392.70624932927 37666.66663013428 37117.454467532574 37386.6193624514 1.1200487183765586 1.085401908921582 1.3932784240968956 1.1455966492745506 1.0871866527966008 1.2639058622477497 1.2141431085079237 1.0074905747686869 0.9928005019039203 1.0 15.190234402777401 -7.767823610121238 23.993191071185127 1.0001090061330387 1.188617447257693 0.4919480205648421 0.0870678197041424 81.95712773343715 308000.13396351144 0.04741930087614678 0.02369036611999136 1.7067754597177854e-08 7.767823610121238 0.18850844112465426 GVEICIAT(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GVEICIATPGR 11 0 P17844-2;P17844;J3KTA4;J3QSF1;J3KRZ1;A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 P17844-2;A0A1X7SBZ2 DDX5;DDX17 Probable ATP-dependent RNA helicase DDX5;Probable ATP-dependent RNA helicase DDX17 1 GVEICIAT(1)PGR;GVEICIAT(1)PGR 92.11200000000001 0.019132 9941500.0 30995.0 29172.0 35523.0 34472.0 36685.0 38569.0 29493.0 32344.0 28523.0 24613.1 True False 36241.84132084536 32068.003368968413 36370.003041727716 32540.64559973192 29496.837595475972 36546.373743155935 26699.20952917095 31495.004271300735 28940.09491478548 29075.260192807607 1.246483817531255 1.102930916398166 1.2508917478483863 1.1191867375887337 1.0144995229577567 1.2569577538018548 0.9182792983491709 1.0832234711726398 0.9953511928310942 1.0 14.827504481899485 -6.635899162283152 0.48508816907238245 0.9907852908520312 1.2173973908017894 0.4022087702287841 0.08842200333112155 1.2106176699882394 0.5955927952539074 0.07737408677637046 0.1195707799714533 2.3126016848701697e-07 6.635899162283152 0.22661209994975828 GVEICIAT(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 1 GVEICIATPGR 11 0 P17844-2;P17844;J3KTA4;J3QSF1;J3KRZ1;A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 P17844-2;A0A1X7SBZ2 DDX5;DDX17 Probable ATP-dependent RNA helicase DDX5;Probable ATP-dependent RNA helicase DDX17 1 GVEICIAT(1)PGR 122.18 0.0016989999999999998 4972600.0 18299.0 27017.0 28852.0 31601.0 32315.0 25710.0 26377.0 23617.0 26329.0 25643.0 True False 18038.05290437438 26954.44379641953 26479.899931940734 33925.04295784571 30414.29523373442 24610.443232937225 27742.671996347803 24714.332038097327 23363.55076333866 30075.358382850292 0.5997618606819369 0.8962301779848322 0.8804516838954851 1.1280012868338953 1.0112695864358312 0.8182926008612653 0.922438617129409 0.8217468840600765 0.7768336611629915 1.0 14.876294308441418 -4.753967035688778 4.256700962087195 0.9190495202282267 0.5663093349407045 0.4767268728394657 0.10004482407086249 0.22971835405451213 8.335492626091753 0.027063947808210555 0.2557706521679122 1.7621097909871423e-05 4.753967035688778 -0.35274018528752227 GVELCFPENET(ph)PPEGK ddPTM_PC-9_Lapatinib_30min_R1 1 GVELCFPENETPPEGK 16 0 A0A590UJ01;Q13535-2;Q13535-3;Q13535 A0A590UJ01 ATR Serine/threonine-protein kinase ATR 1 GVELCFPENET(1)PPEGK 133.86 2.0021e-05 0.0 5105.9 9306.8 10797.0 7687.0 8681.9 11779.0 10085.0 9182.1 8659.5 8169.2 True False 5033.088929692616 9285.250676408088 9909.312337625264 8252.32762308028 8171.247711272133 11275.239628190104 10607.15195371602 9608.733886904065 7684.175921422426 9581.235335225232 0.5253068893098324 0.9691078813470991 1.0342416182174194 0.8613010049696569 0.8528386398391337 1.1768043716384773 1.107075610043626 1.0028700424023336 0.8020026283220179 1.0 13.22599596328592 -4.761791527500814 6.392250395475576 0.9838149084618275 0.5117031549296875 0.6046312248641073 0.10992167128162685 0.08856477945798699 16.334919622796487 0.029056136049228673 0.18252739493058573 1.7306469147981013e-05 4.761791527500814 -0.47211175353213997 GVEPS(ph)PSPIKPGDIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GVEPSPSPIKPGDIK 15 1 Q92890;Q92890-1;Q92890-3;C9JNP9 Q92890 UFD1L Ubiquitin fusion degradation protein 1 homolog 1 GVEPS(0.583)PS(0.417)PIKPGDIK 66.673 0.014811000000000001 5114500.0 54885.0 90314.0 49726.0 61486.0 76944.0 44921.0 65492.0 60229.0 52285.0 45007.0 True False 64175.94647183731 99279.77705556763 50911.65642690518 58041.1387603016 61867.375547125645 42565.263681099 59288.12363898089 58648.05256790049 53049.569211498034 53166.41282478405 1.2070768566488852 1.8673401454176606 0.957590586272772 1.0916880729114218 1.1636552526313295 0.8006043932543966 1.1151424459342711 1.1031034341395536 0.9978023039908469 1.0 15.698227509606124 -5.280703988805815 24.997078075629116 1.0343911596064064 1.5372085327271752 0.5697124038951331 0.17671566732476635 461.59756523705255 598952.2272304564 0.04292278646231101 0.08956290825121807 5.239574395627775e-06 5.280703988805815 0.5028173731207688 GVEPS(ph)PSPIKPGDIK ddPTM_PC-9_Lapatinib_30min_R1 1 GVEPSPSPIKPGDIK 15 1 Q92890;Q92890-1;Q92890-3;C9JNP9 Q92890 UFD1L Ubiquitin fusion degradation protein 1 homolog 1 GVEPS(0.546)PS(0.454)PIKPGDIK 66.82600000000001 0.014662999999999999 38829000.0 44074.0 82839.0 83416.0 98762.0 107130.0 91472.0 88234.0 108990.0 80922.0 95371.0 True False 43445.496677818286 82647.19138511282 76557.85847507177 106025.286940374 100828.82402568363 87559.95579164656 92802.32478772226 114054.07328755694 71807.71221356264 111855.75027613067 0.38840646610091434 0.7388729786451508 0.6844338202200477 0.94787515776915 0.9014183336732746 0.7827935137486741 0.8296607421489507 1.0196531962460529 0.6419671052788599 1.0 16.771279898751736 -4.549852981565754 1.1351855037348715 0.865554997515436 5.332107668446389e-14 0.6018901824043914 0.11507536729843866 1.7035167959652247 1.3050925139668788 0.03360095985812086 1.9933864000065789 2.8193371786817088e-05 4.549852981565754 -0.8655549975153827 GVEPSPS(ph)PIKPGDIK ddPTM_PC-9_AZD4547_30min_R2 2 GVEPSPSPIKPGDIK 15 1 Q92890;Q92890-1;Q92890-3;C9JNP9 Q92890 UFD1L Ubiquitin fusion degradation protein 1 homolog 1 GVEPS(0.203)PS(0.797)PIKPGDIK;GVEPS(0.403)PS(0.597)PIKPGDIK 78.441 0.0056116000000000004 59699000.0 231387.0 277650.0 237722.0 199167.0 237287.0 268534.0 299230.0 283044.0 302565.0 275043.0 True False 304963.2528514147 367394.93275832344 234569.65095520476 153252.12524947597 204343.79592176387 251742.52652934584 325860.8903146793 239306.05350406835 318557.96820131 265413.82828657364 1.1490104144918125 1.3842343299522373 0.8837883559779497 0.5774082165907573 0.7699063656213458 0.9484906199293182 1.2277464682919215 0.9016337055569082 1.2002312398634911 1.0 18.01788401274382 -5.2692719866017725 24.722794888024097 0.9268857152433047 1.2666223760602282 0.3294861387113218 0.18654348079450456 541.9808230269127 1710709.6544229307 0.05302040970715076 0.11373782161076874 5.379327846016484e-06 5.2692719866017725 0.33973666081692355 GVEPSPS(ph)PIKPGDIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GVEPSPSPIKPGDIK 15 1 Q92890;Q92890-1;Q92890-3;C9JNP9 Q92890 UFD1L Ubiquitin fusion degradation protein 1 homolog 1 GVEPS(0.18)PS(0.82)PIKPGDIK;GVEPS(0.012)PS(0.988)PIKPGDIK;GVEPS(0.042)PS(0.958)PIKPGDIK 128.45 0.00047718 60843000.0 216849.6 356995.9 243485.1 278239.0 290742.0 168667.5 258998.9 187597.9 164751.9 170274.3 True False 253557.9543051709 392436.09364829044 249290.7082063843 262650.17089300865 233773.19220891045 159822.27937783615 234464.64920234564 182673.6539014048 167161.0848575272 201143.68269938245 1.2605812467107094 1.9510237079371884 1.2393663318721253 1.30578384251595 1.1622199070417447 0.7945677300574095 1.1656575342351803 0.9081749496175732 0.8310531189157769 1.0 17.61786690252518 -5.999267037710674 1.1423650945961992 0.9447849284658643 1.5914632306578007 0.5824911883547321 0.20373205363200447 0.3334083561607439 0.8849825777959505 0.07598952357835588 0.1513889338915815 1.001689133021882e-06 5.999267037710674 0.6466783021919364 GVEPSPS(ph)PIKPGDIK ddPTM_PC-9_Lapatinib_30min_R1 1 GVEPSPSPIKPGDIK 15 1 Q92890;Q92890-1;Q92890-3;C9JNP9 Q92890 UFD1L Ubiquitin fusion degradation protein 1 homolog 1 GVEPS(0.108)PS(0.892)PIKPGDIK 82.171 0.038949 5429500.0 11250.0 28512.0 23140.0 27469.0 31415.0 25834.0 26002.0 30800.0 22019.0 27389.0 True False 11089.572937002664 28445.98221577207 21237.51852298312 29489.161893897788 29567.231464266355 24729.14004199536 27348.256331236877 32231.080440928017 19538.988349650732 32123.152156451517 0.34522057122515193 0.8855289816276347 0.6611280991214257 0.9180033687315232 0.9204336897033986 0.7698229588913128 0.8513565604658239 1.0033598285732002 0.6082525231175541 1.0 14.971325847042026 -4.758467273405721 24.994982620437202 0.8430550997945192 0.34521989388438307 0.5894512546614317 0.1254590015605759 55.53151286032265 466928.3881499691 0.029315701529984535 0.20032398599019452 1.743944768812108e-05 4.758467273405721 -0.49783520591013614 GVEPSPS(ph)PIKPGDIKR ddPTM_PC-9_AZD4547_30min_R2 2 GVEPSPSPIKPGDIKR 16 2 Q92890;Q92890-1;Q92890-3 Q92890 UFD1L Ubiquitin fusion degradation protein 1 homolog 1 GVEPS(0.037)PS(0.963)PIKPGDIKR;GVEPS(0.042)PS(0.958)PIKPGDIKR 60.196000000000005 0.014852 260850000.0 379453.0 267813.0 371887.0 481593.0 511173.0 428814.0 367505.0 394664.0 320552.0 457142.0 True False 500111.1608872906 354378.31488134305 366955.53539335117 370569.1743876792 440205.4524382524 402000.1927918067 400212.2330484792 333677.7472764983 337495.72430012224 441137.59772319446 1.133685189084928 0.8033282964552678 0.8318391750947713 0.8400308119286726 0.9978869511695374 0.9112807316053216 0.9072276657307383 0.7564028751996669 0.765057719047322 1.0 18.75086919958523 -7.681606591566781 10.836713726913835 0.8206354632131667 0.9101407371882072 0.08416169859641875 0.10932530114952127 0.914275510133376 118.07713156323321 0.050547014493959104 0.029145998824499964 2.081581447176949e-08 7.681606591566781 0.08950527397504049 GVEPSPS(ph)PIKPGDIKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GVEPSPSPIKPGDIKR 16 2 Q92890;Q92890-1;Q92890-3 Q92890 UFD1L Ubiquitin fusion degradation protein 1 homolog 1 GVEPS(0.02)PS(0.98)PIKPGDIKR;GVEPS(0.022)PS(0.978)PIKPGDIKR 61.821000000000005 0.012764 93654000.0 111266.0 100649.0 102240.0 137235.0 137294.0 146401.0 147731.0 136837.0 126461.0 101949.0 True False 130101.13619632777 110640.76755393202 104677.78934735921 129546.16787187307 110392.22627322529 138723.47383576914 133736.85020018124 133245.1737407857 128310.2528842926 120431.54667216016 1.0802911678157738 0.9187025377588093 0.8691891139811899 1.0756830037608403 0.916638782143486 1.1518865087185457 1.110480217980102 1.1063975961672812 1.0654206180178016 1.0 16.877853825554922 -6.76022661556086 24.999999999987836 1.0949645417986584 0.969171579537976 0.3826345457842597 0.07245568133849449 32.03387367248454 660351.4648669922 0.02411433381620633 0.0228513872608937 1.7368942780155035e-07 6.76022661556086 -0.12579296226068248 GVEPSPS(ph)PIKPGDIKR ddPTM_PC-9_Lapatinib_30min_R1 2 GVEPSPSPIKPGDIKR 16 2 Q92890;Q92890-1;Q92890-3 Q92890 UFD1L Ubiquitin fusion degradation protein 1 homolog 1 GVEPS(0.049)PS(0.951)PIKPGDIKR;GVEPS(0.147)PS(0.853)PIKPGDIKR 69.92 0.006603399999999999 237900000.0 540280.0 432290.0 459710.0 459550.0 463550.0 409420.0 299600.0 363970.0 471100.0 357690.0 True False 532575.5081247838 431289.05906481773 421914.4183319166 493346.84001386055 436284.9003743644 391910.0610046353 315111.8220459414 380881.37493781163 418039.75709707383 419516.23990803317 1.2694991455909683 1.0280628448599878 1.0057165329866828 1.1759898499328956 1.0399714215354505 0.9341952080104223 0.7511314034351103 0.9079061516696204 0.9964805109540383 1.0 18.678367134401775 -6.693041847264677 3.2430058715188834 0.8993127127617764 1.1051110488439082 0.496560097115031 0.09508631099719932 0.21095423304279748 4.474050915083303 0.034253185141281395 0.033183604529711634 2.027487347737786e-07 6.693041847264677 0.20579833608213183 GVGDDQLGEES(ph)EERDDHLLPM ddPTM_PC-9_AZD4547_30min_R2 1 GVGDDQLGEESEERDDHLLPM 21 1 F5GX30;P20645;H0YF90 F5GX30 M6PR Cation-dependent mannose-6-phosphate receptor 1 GVGDDQLGEES(1)EERDDHLLPM 68.291 0.005193199999999999 4275900.0 6766.5 6635.7 13055.0 11669.0 11377.0 8184.1 9019.8 13469.0 10697.0 9340.1 True False 8918.106248056694 8780.560256813998 12881.882170014534 8978.892334252834 9797.499931314853 7672.346933233101 9822.544726332082 11387.675536829218 11262.421581641676 9013.105941905185 0.9894598272270602 0.9741991621323346 1.4292389608028473 0.9962040158106564 1.0870281559393125 0.8512433985227654 1.089806864541947 1.2634574152605709 1.2495605459687997 1.0 13.137808633189815 -7.596655089946062 7.773569522457669 1.1907136238632094 1.0589131453544465 0.09637694697028909 0.155609247965475 0.5456787141148953 49.68136616274349 0.0752684010670129 0.04324242005244184 2.5313075242021646e-08 7.596655089946062 -0.13180047850876297 GVGDDQLGEESEERDDHLLPM ddPTM_PC-9_AZD4547_30min_R2 1 GVGDDQLGEESEERDDHLLPM 21 1 F5GX30;P20645;H0YF90 F5GX30 M6PR Cation-dependent mannose-6-phosphate receptor 0 75.743 0.008526100000000002 2551800.0 6654.3 8999.9 13158.0 16258.0 14594.0 8905.9 10504.0 15326.0 9732.2 10421.0 False True 8770.228981961667 11908.941672363173 12983.516322715524 12509.969283596076 12567.875010776917 8349.012665128808 11438.835651055697 12957.71885644403 10246.624223319912 10056.163961905533 0.8721247003514255 1.184242989421839 1.291100301456828 1.2440100749138514 1.249768307118517 0.8302383191797881 1.1374949428418193 1.2885349627880056 1.018939653543426 1.0 13.295792457202886 GVGDDQLGEESEERDDHLLPM ddPTM_PC-9_Lapatinib_30min_R1 1 GVGDDQLGEESEERDDHLLPM 21 1 F5GX30;P20645;H0YF90 F5GX30 M6PR Cation-dependent mannose-6-phosphate receptor 0 82.755 0.0036618 2656100.0 14646.0 12370.0 13062.0 10502.0 11712.0 13894.0 8652.8 9084.3 15448.0 9775.7 False True 14437.145354252536 12341.358025010535 11988.092780778108 11274.352113644998 11023.123186677945 13299.786008495914 9100.799645524437 9506.389741867615 13708.083565348315 11465.416719698533 1.2591906345146904 1.0763985580922726 1.045587183951332 0.9833355724676566 0.9614236844736144 1.1599915060780812 0.7937609131893577 0.8291359986536602 1.1956027330255425 1.0 13.485001171320912 -1.5228896658290936 0.7262865661306921 0.9748173359177444 43.61002300555085 0.3180764800315552 0.11770856366135275 388.971203272493 1.8547963678344181 0.04519090474939436 27043.449984900668 0.02999924564470117 1.5228896658290936 42.63520566963311 GVGISVLEMSHR ddPTM_PC-9_AZD4547_30min_R2 1 GVGISVLEMSHR 12 0 Q9Y617-2;Q9Y617 Q9Y617-2 PSAT1 Phosphoserine aminotransferase 0 62.799 0.042111 2294900.0 18707.0 17508.0 23966.0 28463.0 28794.0 29869.0 28990.0 30261.0 29195.0 23085.0 False True 24655.436870227833 23167.118612399525 23648.19518089379 21901.29509896636 24796.450120618774 28001.28670821953 31570.05383892848 25584.857778601905 30738.188097226193 22276.801176527144 1.1067763578285663 1.0399661256935981 1.0615615318150646 0.9831436266551388 1.1131064071598646 1.2569707152445309 1.417171773844871 1.1484978285643825 1.3798295299961978 1.0 14.443254464198494 -6.658381605409072 3.7606957275315285 1.2612880068566539 1.0483413953042193 0.3897341716824453 0.11297435122000116 0.20823484311336152 5.602280603037152 0.03664095925027131 0.03618009573357386 2.1959295078412702e-07 6.658381605409072 -0.21294661155243455 GVGISVLEMSHR ddPTM_PC-9_Lapatinib_30min_R1 2 GVGISVLEMSHR 12 0 Q9Y617-2;Q9Y617 Q9Y617-2 PSAT1 Phosphoserine aminotransferase 0 ; 114.71 0.0006347000000000001 2624700.0 54887.0 72035.0 70561.0 67648.0 70776.0 71291.0 68374.0 63690.0 71201.0 69448.0 False True 54104.30131495694 71868.20738331728 64759.74695333667 72623.05958711267 66613.09483096986 68242.05011743787 71914.07116344858 66649.26991177624 63181.59360023082 81451.99426635684 0.6642477179629269 0.8823382168925228 0.7950664380489603 0.8916056659045991 0.8178203054567066 0.8378192668221109 0.8829012943290472 0.8182644330822142 0.7756911806679672 1.0 16.313662401602407 -12.201234821881823 2.1956769177238393 6.426149118204072 0.824208210510708 0.4208712698448369 0.06357538556677803 3365787.4159066556 229053.6202644743 91139552.11964726 0.015123492352948147 6.291659025257609e-13 12.201234821881823 -5.601940907693364 GVGS(ph)PEPGPTAPYLGR ddPTM_PC-9_AZD4547_30min_R2 3 GVGSPEPGPTAPYLGR 16 0 Q9C0B5;Q9C0B5-2 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5 1 GVGS(0.968)PEPGPT(0.03)APY(0.002)LGR;GVGS(0.987)PEPGPT(0.013)APYLGR;GVGS(0.941)PEPGPT(0.056)APY(0.004)LGR 95.195 0.002496 37897300.0 72667.0 140561.0 143594.0 179337.0 151475.0 106273.0 139783.0 170494.0 121610.0 107546.0 True False 95773.5944325038 185994.59442983152 141689.84973734722 137993.62537902978 130445.31089882352 99627.73251004775 152223.41620444797 144148.0698623624 128038.05632826447 103780.8472744546 0.9228445994396717 1.7921861240731423 1.3652793695414724 1.329663700028363 1.256930486931304 0.9599818764880219 1.4667775432771726 1.3889660149059517 1.2337349298147493 1.0 16.663180693742397 -13.570896952420856 0.22650435362802657 1.8708667391293732e-07 1.3543582359129336 0.125411678929796 0.23457869054841404 204.59736471424011 3.021012740860658 94.49015958780889 0.42446075741569167 2.6859816885609505e-14 13.570896952420856 1.3543580488262597 GVGS(ph)PEPGPTAPYLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GVGSPEPGPTAPYLGR 16 0 Q9C0B5;Q9C0B5-2 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5 1 GVGS(0.9)PEPGPT(0.023)APY(0.076)LGR;GVGS(0.796)PEPGPT(0.055)APY(0.149)LGR 78.508 0.0097089 17306700.0 70838.0 70423.0 64787.0 49329.0 125353.0 62843.0 54222.0 68836.0 69838.0 54161.0 True False 82829.47428572485 77414.13003060705 66331.7677860657 46565.25605677578 100790.97950403999 59547.4024512212 49085.699626715024 67029.12793777075 70859.24862948454 63979.960561759945 1.2946159009549474 1.2099746444182171 1.0367584975616788 0.7278100150097198 1.575352323119148 0.9307195867015268 0.7672042807737046 1.0476581627940744 1.1075225431107294 1.0 15.96533248270371 GVGS(ph)PEPGPTAPYLGR ddPTM_PC-9_Lapatinib_30min_R1 2 GVGSPEPGPTAPYLGR 16 0 Q9C0B5;Q9C0B5-2 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5 1 GVGS(0.981)PEPGPT(0.017)APY(0.002)LGR;GVGS(1)PEPGPTAPYLGR 136.81 1.1365e-05 30012000.0 156236.0 184530.0 65583.0 43790.0 66434.0 45913.0 55630.0 41027.0 104202.0 28426.0 True False 154008.04598982638 184102.73212248908 60191.01889770104 47010.46267915771 62526.48273426931 43949.408018430484 58510.24920031952 42933.264196427095 92465.67346429461 33339.39622473588 4.619401171865297 5.522077570975794 1.8054021882088802 1.4100574096263536 1.8754533619261624 1.3182424697248296 1.7549882669113348 1.2877636987490833 2.773465747279805 1.0 15.02494035695516 -5.267704203222524 24.703653024523298 1.6543793098794137 5.070739485233716 0.8829704241848593 0.4976817553410221 103.52899307848 408240.5728236203 0.12015588891184277 0.2605642679342068 5.398782068828098e-06 5.267704203222524 3.4163601753543023 GVGSGPHPPDT(ph)QQPSPSK ddPTM_PC-9_AZD4547_30min_R2 1 GVGSGPHPPDTQQPSPSK 18 0 Q68CZ2;Q68CZ2-2;E9PCX8 Q68CZ2 TNS3 Tensin-3 1 GVGSGPHPPDT(0.64)QQPS(0.336)PS(0.024)K 101.48 0.0010974000000000001 104650000.0 121980.0 93309.0 164420.0 233050.0 230400.0 187480.0 171720.0 203140.0 172870.0 210140.0 True False 160767.10265838384 123469.30949305391 162239.68336988037 179323.92308660757 198412.93699349012 175756.84596260314 187002.74733428058 171749.3806928125 182007.5552789005 202783.06256163795 0.7928034059033755 0.6088738770059958 0.8000652585102662 0.884314107999529 0.9784492574826387 0.866723501175943 0.9221812954789516 0.8469611737943229 0.8975481136329 1.0 17.62957763082742 -5.600244851822198 3.1314298415387536 0.9090514383612482 0.6999702668314883 0.6641462332750945 0.06102537071562079 0.1348016994387199 2.644832294415471 0.01621596793849307 0.03183677255783145 2.510470648784372e-06 5.600244851822198 -0.2090811715297599 GVGSGPHPPDTQQPS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 2 GVGSGPHPPDTQQPSPSK 18 0 Q68CZ2;Q68CZ2-2;E9PCX8 Q68CZ2 TNS3 Tensin-3 1 GVGSGPHPPDT(0.035)QQPS(0.76)PS(0.205)K;GVGSGPHPPDT(0.012)QQPS(0.988)PSK 197.1 5.9429e-54 4029100.0 24574.0 24237.0 43535.0 58421.0 56426.0 50796.0 41679.0 53449.0 43425.0 49061.0 True False 32388.020829046814 32071.13626963259 42957.69745473631 44952.94104545243 48592.22388365752 47619.71809001708 45388.35025707831 45189.68518583299 45720.35684610543 47343.38932300617 0.6841086219678001 0.677415299754381 0.9073642185111013 0.9495082985874836 1.026378224679501 1.0058366916894272 0.9587051308771037 0.9545088729816265 0.9657178647302287 1.0 15.530875372154705 -5.355159753855026 2.5185077117826418 0.980086363401909 0.6682212412288148 0.9577344876022972 0.024746362882113373 0.05625997118523927 0.6806405371340718 0.007570286259538626 0.021443082448451584 4.414080469284236e-06 5.355159753855026 -0.31186512217309426 GVGSGPHPPDTQQPS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 GVGSGPHPPDTQQPSPSK 18 0 Q68CZ2;Q68CZ2-2;E9PCX8 Q68CZ2 TNS3 Tensin-3 1 GVGSGPHPPDT(0.157)QQPS(0.609)PS(0.234)K;GVGSGPHPPDT(0.214)QQPS(0.449)PS(0.336)K;GVGSGPHPPDT(0.028)QQPS(0.903)PS(0.069)K;GVGSGPHPPDT(0.021)QQPS(0.965)PS(0.013)K;GVGSGPHPPDT(0.001)QQPS(0.771)PS(0.229)K;GVGSGPHPPDTQQPS(0.973)PS(0.027)K 233.65 3.4799999999999998e-43 187299000.0 216355.0 252389.0 271637.0 338381.0 368023.0 345967.0 358857.0 330473.0 325440.0 283776.0 True False 252979.62829396647 277444.5119392081 278113.8562690598 319422.60961600434 295911.53502521064 327823.8814799043 324863.4670603093 321798.4339150862 330198.94432800874 335222.3424304195 0.7546621936348894 0.8276432588821131 0.8296399764188944 0.9528679004511919 0.8827321379589476 0.9779296901964376 0.9690984935699495 0.9599552093753427 0.9850147276401976 1.0 18.354758781706103 -3.646112118011909 0.3437951669058757 0.996912600724161 0.2790158111915285 0.8836973342924281 0.027309135274711845 4.297661497180505 0.22118067056012328 0.023747120332565652 1.4926445888327067 0.0002258852546715243 3.646112118011909 -0.7178967895326325 GVGSGPHPPDTQQPS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 3 GVGSGPHPPDTQQPSPSK 18 0 Q68CZ2;Q68CZ2-2;E9PCX8 Q68CZ2 TNS3 Tensin-3 1 GVGSGPHPPDT(0.086)QQPS(0.685)PS(0.228)K;GVGSGPHPPDTQQPS(0.855)PS(0.145)K;GVGSGPHPPDTQQPS(0.999)PS(0.001)K 224.03 8.1488e-35 108342400.0 88609.0 62096.0 84536.0 65429.0 79377.0 85395.0 73903.0 70232.0 91214.0 54425.0 True False 87345.41941109937 61952.2205271669 77585.77639839657 70240.86692474558 74708.20092118646 81742.8549154677 77729.33572984373 73495.23511452129 80940.518793998 63832.28873324594 1.3683579446150584 0.9705467523820771 1.2154628627312145 1.1003971237547345 1.170382613623503 1.2805878739060996 1.2177118707849144 1.1513802273588627 1.268018433934698 1.0 15.961998756700924 -4.694478378768861 23.76497951516388 1.1643558379301917 1.3683748671308562 0.29185647771056766 0.09928989237524963 46081.05084309377 16349568.93922753 0.023699168897848656 153.0888742140864 2.0207920340627278e-05 4.694478378768861 0.2040190292006645 GVGSGPHPPDTQQPSPS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 GVGSGPHPPDTQQPSPSK 18 0 Q68CZ2;Q68CZ2-2;E9PCX8 Q68CZ2 TNS3 Tensin-3 1 GVGSGPHPPDTQQPS(0.362)PS(0.637)K 111.57 0.00011268 92312000.0 215340.0 168250.0 193090.0 167760.0 200640.0 217270.0 182380.0 179140.0 218720.0 145870.0 True False 212269.21211148068 167860.42746224892 177214.8855489545 180097.6300309546 188838.74967341722 207977.86858110747 191822.74400780644 187463.49838272276 194085.4503762936 171083.4351404428 1.2407350363127112 0.9811611938026139 1.0358389484258272 1.052688881790993 1.1037816111092171 1.2156516988940393 1.1212233601127934 1.0957431280756873 1.1344491079277685 1.0 17.384340554558456 -4.729888229703154 24.434595578183206 1.0889544307664127 1.2407363687319182 0.3399391344140914 0.0656489941302955 4293.711964285273 3324990.0286533027 0.017467325784405095 2.424383055660248 1.8625664262341403e-05 4.729888229703154 0.15178193796550543 GVHIHQAGGS(ph)PPASSTSSSSLTNDVAK ddPTM_PC-9_AZD4547_30min_R2 2 GVHIHQAGGSPPASSTSSSSLTNDVAK 27 0 Q8N122-3;Q8N122;I3L436 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 1 GVHIHQAGGS(0.821)PPAS(0.008)S(0.008)T(0.148)S(0.012)S(0.001)SSLTNDVAK;GVHIHQAGGS(0.398)PPAS(0.049)S(0.049)T(0.122)S(0.049)S(0.049)S(0.062)S(0.198)LT(0.024)NDVAK 96.133 1.6013e-09 69878000.0 40435.3 28987.0 77492.0 124855.0 87762.0 87036.0 64227.0 100782.0 71026.0 83460.0 True False 53292.88429351166 38356.48087831992 76464.40544762659 96071.60874052085 75577.76118239015 81593.62516109014 69943.0785758145 85208.45763996756 74780.28935754711 80538.09080324677 0.6617103008277823 0.47625267119907483 0.9494191467044814 1.1928716931622108 0.9384101414450633 1.0131060265684968 0.8684471891279903 1.0579895399821486 0.9285083444582033 1.0 16.29738365241252 -5.318175266917118 6.1625299074939255 0.9989356324447263 0.5697295454365812 0.7711300016454676 0.09262333690923642 0.08411211217933481 6.999114493024941 0.023653368987951822 0.05070094648381303 4.806453367118881e-06 5.318175266917118 -0.4292060870081451 GVHIHQAGGS(ph)PPASSTSSSSLTNDVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GVHIHQAGGSPPASSTSSSSLTNDVAK 27 0 Q8N122-3;Q8N122;I3L436 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 1 GVHIHQAGGS(0.996)PPAS(0.001)S(0.001)T(0.003)SSSSLTNDVAK;GVHIHQAGGS(0.997)PPASST(0.002)S(0.001)SSSLTNDVAK 142.32 2.808e-10 37006000.0 21334.5 25488.0 44495.0 48482.0 55321.0 54812.0 47922.0 41132.0 46612.0 33434.0 True False 24946.00947441766 28018.280195676227 45555.92954822719 45765.71072076472 44481.247175121316 51937.562228988674 43382.481234765204 40052.32858295643 47293.612318759595 39495.31953660162 0.6316193859705165 0.7094076089120068 1.1534513477225827 1.1587628928625864 1.1262409748045985 1.3150308147489835 1.0984208190684777 1.0141031659672637 1.197448529943682 1.0 15.269394073815759 -5.22813481049213 4.740897266063845 1.14040896677881 0.6556769011001483 0.8233523317453333 0.08578472094402378 0.07344848919400482 4.19862459520923 0.022366106688692256 0.06023624144197828 5.913780344703717e-06 5.22813481049213 -0.48473206567866167 GVHIHQAGGS(ph)PPASSTSSSSLTNDVAK ddPTM_PC-9_Lapatinib_30min_R1 1 GVHIHQAGGSPPASSTSSSSLTNDVAK 27 0 Q8N122-3;Q8N122;I3L436 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 1 GVHIHQAGGS(0.996)PPASST(0.003)SSSS(0.001)LTNDVAK 101.29 8.081100000000001e-10 18566000.0 11727.0 11882.0 18964.0 13440.0 17549.0 19243.0 15770.0 15226.0 24381.0 11533.0 True False 11559.77082953158 11854.487959027898 17404.853123156943 14428.422434525693 16516.80232266147 18420.021747623934 16586.49343679738 15933.455545245795 21634.95503668805 13526.463683243463 0.8546040635773698 0.8763922512661751 1.2867260453830232 1.0666810463106906 1.221073202090686 1.361776601702823 1.2262254071139578 1.1779468690685286 1.599453895957253 1.0 13.72349709443726 -4.8915934517433115 0.8340752295849476 1.274540287429747 0.593472227796619 0.44328722897278305 0.1610395481153332 1.8634096959984483 1.117550073684581 0.05821395890550922 1.1379129268963977 1.2835315496773561e-05 4.8915934517433115 -0.6810680596331279 GVHIHQAGGSPPASST(ph)SSSSLTNDVAK ddPTM_PC-9_AZD4547_30min_R2 1 GVHIHQAGGSPPASSTSSSSLTNDVAK 27 0 Q8N122-3;Q8N122;I3L436 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 1 GVHIHQAGGS(0.079)PPAS(0.008)S(0.008)T(0.686)S(0.217)S(0.002)S(0.001)S(0.001)LTNDVAK 121.19 6.1907e-12 29148000.0 13766.0 10682.0 28951.0 40977.0 35847.0 37086.0 25651.0 33233.0 20611.0 31145.0 True False 18143.30164941232 14134.747602104846 28567.090823752646 31530.38573833903 30870.26281426064 34767.00655733472 27933.889307428566 28097.603468367775 21700.45538180954 30054.62302980022 0.603677565059545 0.47030194283554133 0.9505057107329999 1.0491026857024806 1.0271385797669692 1.1567939655360842 0.9294373541045958 0.9348845746795097 0.7220338568310364 1.0 14.875299304235549 -5.277378837500071 11.97611113243618 0.9788670302556481 0.5369751539521737 0.716139623592297 0.10927366445108361 0.4640028680816135 349.0103461152336 0.030004505874963262 0.06445623543538322 5.279844870262059e-06 5.277378837500071 -0.4418918763034745 GVIDYDRDR ddPTM_PC-9_AZD4547_30min_R2 1 GVIDYDRDR 9 1 H0YIQ2;P49750-3;P49750-1;P49750;F8VU51;H0YI23 H0YIQ2 YLPM1 YLP motif-containing protein 1 0 90.601 0.01095 7298400.0 71736.0 116490.0 66707.0 113110.0 89458.0 76193.0 77740.0 77407.0 69610.0 79707.0 False True 94546.55579850668 154143.114413892 65822.42159442056 87034.23703207976 77038.30085748123 71428.63966518365 84658.7093976648 65445.526785903865 73289.44248836853 76916.48219092257 1.2292106074719151 2.004032296111476 0.8557648467468356 1.1315420902381215 1.0015837784449928 0.9286519303870793 1.100657583215057 0.8508647941471709 0.9528444411491547 1.0 16.231005161445076 -5.276663783513855 24.9972696774003 0.9813938594552803 1.616621478022274 0.6357502509188471 0.19342024467760827 389.4663629434589 639472.8559096993 0.046211769810275825 0.09677134569238542 5.288545150855313e-06 5.276663783513855 0.6352276185669937 GVIS(ph)TPVIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GVISTPVIR 9 0 Q9NZB2-4;Q9NZB2;Q9NZB2-6;A0A0C4DG79;A0A494C0Y9 Q9NZB2-4 FAM120A Constitutive coactivator of PPAR-gamma-like protein 1 1 GVIS(0.5)T(0.5)PVIR 97.965 0.004614 8430500.0 67687.0 59934.0 69930.0 59809.0 74949.0 47992.0 47722.0 44230.0 44566.0 42940.0 True False 79145.07222081166 65883.85142999297 71597.39641100202 56458.09563339422 60263.281475898286 45475.21503491249 43201.42668263979 43069.00936555875 45217.69343941136 50724.682087147004 1.5602872007130042 1.2988519339914621 1.4114902935812366 1.1130300538187108 1.188046509041961 0.8965105972824883 0.8516845232941634 0.849074012757034 0.8914337474156188 1.0 15.630400297584933 -6.095712113310688 0.8431473561561588 0.8704313705572132 1.4835316177703013 0.856196592977816 0.0909736275804513 0.22945760710574875 0.337420206300794 0.043323895175335254 0.08969881555278889 8.022096588012775e-07 6.095712113310688 0.6131002472130881 GVIST(ph)PVIR ddPTM_PC-9_AZD4547_30min_R2 2 GVISTPVIR 9 0 Q9NZB2-4;Q9NZB2;Q9NZB2-6;A0A0C4DG79;A0A494C0Y9 Q9NZB2-4 FAM120A Constitutive coactivator of PPAR-gamma-like protein 1 1 GVIS(0.018)T(0.982)PVIR;GVIS(0.005)T(0.995)PVIR 124.34 0.0035740999999999998 25046000.0 129349.0 143679.0 158203.0 239745.0 197845.0 223360.0 164209.0 273910.0 160507.0 204940.0 True False 170479.2913736621 190120.42695401824 156105.12485199617 184475.4942733264 170377.63680328627 209393.2638905859 178823.2828850155 231583.5033256287 168991.07233846496 197765.11297888082 0.8620291456151189 0.9613446178159899 0.7893461212679433 0.9328009955579293 0.8615151289170034 1.058797786609344 0.9042205684888007 1.1710028115543276 0.8545039607491913 1.0 17.59342842241714 -6.751168572458855 24.997559258296842 1.002549925184787 0.8835888601132726 0.2925276135239342 0.0902410905113543 253.0773868946659 615950.3153607401 0.02767168335900561 0.027382900346138654 1.7735009585648222e-07 6.751168572458855 -0.11896106507151427 GVIST(ph)PVIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GVISTPVIR 9 0 Q9NZB2-4;Q9NZB2;Q9NZB2-6;A0A0C4DG79;A0A494C0Y9 Q9NZB2-4 FAM120A Constitutive coactivator of PPAR-gamma-like protein 1 1 GVIS(0.079)T(0.921)PVIR;GVIS(0.069)T(0.931)PVIR;GVIS(0.063)T(0.937)PVIR 148.69 0.0007633999999999999 13477400.0 161908.0 135629.0 196732.0 144632.0 187826.0 129271.0 145798.0 106686.0 109360.0 106584.0 True False 189315.82657123482 149093.3507791655 201422.83699026433 136528.73794327036 151022.84362022264 122491.80119141054 131986.95795388974 103885.60554316053 110959.18311120628 125906.83548151993 1.5036183369013496 1.1841561278938568 1.599776820852815 1.0843631914115535 1.1994808942870234 0.9728764981102982 1.0482906464062647 0.8250990118674567 0.8812800566931285 1.0 16.941997083527063 -6.385176871244968 0.8999218069888164 0.9069325166948873 1.4165712707430265 0.6789432501127248 0.13565926693197158 0.3313093179996331 0.5822614699302867 0.06745293133823874 0.09476479198953469 4.119297219826118e-07 6.385176871244968 0.5096387540481392 GVIST(ph)PVIR ddPTM_PC-9_Lapatinib_30min_R1 2 GVISTPVIR 9 0 Q9NZB2-4;Q9NZB2;Q9NZB2-6;A0A0C4DG79;A0A494C0Y9 Q9NZB2-4 FAM120A Constitutive coactivator of PPAR-gamma-like protein 1 1 GVIS(0.051)T(0.949)PVIR;GVIS(0.076)T(0.924)PVIR 125.71 0.0034664 22499000.0 252840.0 221950.0 265870.0 242830.0 185996.0 231470.0 153232.0 126173.0 218440.0 119859.0 True False 249234.45523482212 221436.08841156776 244011.1948878795 260688.52825713373 175056.0809622056 221570.56768292436 161165.60319006568 132035.4581971824 193836.98692482413 140576.4684479213 1.7729457709855247 1.5752002511971066 1.7357897632652308 1.854425076510652 1.245273002622468 1.5761568783825906 1.146462170870169 0.9392429590454319 1.3788722185508167 1.0 17.100995591644313 -6.861942608752501 1.0389073700066078 1.094213720902057 1.7192277696876526 0.6744520075474809 0.17825146023353816 0.3036117809722359 0.6928198830127724 0.10249114295328161 0.08409385981818024 1.3742235642268603e-07 6.861942608752501 0.6250140487855955 GVISYQT(ph)LPR ddPTM_PC-9_AZD4547_30min_R2 2 GVISYQTLPR 10 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;Q9HAU0-3 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 GVISYQT(1)LPR;GVIS(0.002)Y(0.001)QT(0.998)LPR 114.76 0.0028863000000000005 34182000.0 48032.0 46190.0 81364.0 106390.0 69724.0 76267.0 65496.0 40837.0 48885.0 62154.0 True False 63305.17687233567 61120.01420531949 80285.0601977068 81863.4292091146 60044.02612384601 71498.01243348546 71325.01711743578 34526.57999090466 51468.961299294504 59978.007378205206 1.0554731582386563 1.0190404262667996 1.3385749828508102 1.3648907789301137 1.0011007158878171 1.1920704864807896 1.189186173986731 0.5756540021943264 0.8581305640039866 1.0 15.872145972557464 -7.7421992078665935 24.990345981608808 0.7876692250401395 1.1691034543618746 0.5363351937374783 0.1505454995566346 165.2404785789982 214625.24308322568 0.07187838846185053 0.041416939191652194 1.810509434005763e-08 7.7421992078665935 0.3814342293217351 GVISYQT(ph)LPR ddPTM_PC-9_Lapatinib_30min_R1 2 GVISYQTLPR 10 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;Q9HAU0-3 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 GVIS(0.002)Y(0.003)QT(0.995)LPR;GVIS(0.004)YQT(0.996)LPR 96.06700000000001 0.013872999999999998 42922000.0 102937.0 88008.0 92424.0 69953.0 59065.0 83483.0 62520.0 57549.0 56204.0 38982.0 True False 101469.09950366606 87804.22288319534 84825.2554869571 75097.57697636721 55590.9128262579 79912.62669837795 65756.9796872906 60222.9366329535 49873.713665641924 45719.98675975 2.219359774465099 1.9204778720647964 1.8553210859989526 1.6425546527603119 1.2158995827881094 1.7478707314222093 1.4382545654011507 1.3172124687921236 1.090851445948989 1.0 15.480537365305564 -1.5228787452803376 0.18007468200659602 0.9411487833784391 6.346739422027973 0.8337323160849288 0.15352459476677568 23.113070090740067 0.2605118956160467 0.3642253889361274 34.18554243637211 0.029999999999999995 1.5228787452803376 5.405590638649533 up GVLDLDRPGEPAGEES(ph)PGPLQER ddPTM_PC-9_AZD4547_30min_R2 1 GVLDLDRPGEPAGEESPGPLQER 23 1 A0A669KBI7;Q9UMN6 A0A669KBI7 KMT2B Histone-lysine N-methyltransferase 2B 1 GVLDLDRPGEPAGEES(1)PGPLQER 48.118 0.0204 3766500.0 4920.2 5083.5 15635.0 20626.0 17260.0 15778.0 7645.6 15767.0 9737.0 12553.0 True False 6484.72125348238 6726.641961739373 15427.669684272481 15870.994368523337 14863.74692928666 14791.399165766781 8326.04358851023 13330.572439615875 10251.67794152052 12113.523290835836 0.5353290779065265 0.5553002045926833 1.2735906237901795 1.310188125079193 1.2270374665091397 1.2210649875050656 0.6873345919769749 1.1004702859407358 0.8463002625566547 1.0 13.564330922115078 -5.247984524817591 23.830805980882335 1.0908590811199244 0.545314397734669 0.5705243540271729 0.18659646820786163 314.7505167137969 557470.77531798 0.051103930273728324 0.1333101285387317 5.649571055274312e-06 5.247984524817591 -0.5455446833852553 GVLDLDRPGEPAGEES(ph)PGPLQER ddPTM_PC-9_Lapatinib_30min_R1 1 GVLDLDRPGEPAGEESPGPLQER 23 1 A0A669KBI7;Q9UMN6 A0A669KBI7 KMT2B Histone-lysine N-methyltransferase 2B 1 GVLDLDRPGEPAGEES(1)PGPLQER 55.621 0.004379699999999999 2958200.0 8976.9 7829.7 13167.0 8033.7 14640.0 13790.0 10478.0 13369.0 14026.0 9768.7 True False 8848.88775983816 7811.5708107053315 12084.460086089828 8624.52509763758 13778.903983347425 13200.233846060071 11020.499570752256 13990.172545933983 12446.244179672152 11457.206779025444 0.7723425028897708 0.6818041221884787 1.0547474894328248 0.7527598361431673 1.2026407700498416 1.1521336832486575 0.9618836234087472 1.2210805666478506 1.0863244785332256 1.0 13.48396774325783 -5.686364334956382 0.987918163567219 1.1071765372832143 0.7122788794014493 0.5128285874754106 0.12829957916995516 0.5363742355637915 0.9480169247879712 0.04844442554795681 0.1661396000279223 2.058901950520731e-06 5.686364334956382 -0.394897657881765 GVLFGVPGAFT(ph)PGCSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GVLFGVPGAFTPGCSK 16 0 P30044-2;P30044;P30044-3 P30044-2 PRDX5 Peroxiredoxin-5, mitochondrial 1 GVLFGVPGAFT(0.998)PGCS(0.002)K 150.76 7.5684e-05 1807700.0 15459.0 17878.0 12493.0 12960.0 18198.0 16743.0 15144.0 14463.0 13121.0 13341.0 True False 18075.90337083235 19652.80968841414 12790.880499966337 12233.893216886914 14632.232535436055 15864.967605633032 13709.45068693469 14083.361574815199 13312.869802506757 15759.617692702112 1.1469760068610582 1.2470359415834604 0.8116237810698591 0.7762810910414487 0.928463673469178 1.0066848013057896 0.8699101053246486 0.8936359910137195 0.8447457331830845 1.0 13.943944916911462 -5.258447857899901 24.999929726774884 0.8881789686074647 1.1970059987109873 0.7351154998516447 0.07335411274979094 126.0447719117099 1053333.635551912 0.019626680661907682 0.047493204145108915 5.515084134018464e-06 5.258447857899901 0.30882703010352264 GVLHTFS(ph)PSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GVLHTFSPSPK 11 0 Q86YP4-2;Q86YP4;Q86YP4-3 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 1 GVLHT(0.001)FS(0.992)PS(0.007)PK 140.14 0.00011822 7957900.0 55469.0 58009.0 52378.0 59738.0 65519.0 62266.0 56066.0 56386.0 51718.0 35242.0 True False 64858.80613731155 63767.75015187477 53626.89016467114 56391.073533209084 52681.02228207688 59000.66134697163 50755.02259731117 54905.927245905375 52474.277909156626 41631.09562448148 1.5579413696518436 1.5317336523417284 1.2881450598464539 1.3545421442151018 1.2654248342937535 1.4172257650667222 1.2191613464879434 1.318868178276277 1.2604587297553305 1.0 15.345373906588872 -1.5228787452803376 0.03613490540650162 6.580187381476733e-11 3.3980273341570557 0.7534552019364313 0.07565945445993018 493.9971832420222 1.3683369345107592 37.42400657662462 108.33755981867155 0.029999999999999995 1.5228787452803376 3.3980273340912537 GVLHTFS(ph)PSPK ddPTM_PC-9_Lapatinib_30min_R1 1 GVLHTFSPSPK 11 0 Q86YP4-2;Q86YP4;Q86YP4-3 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 1 GVLHTFS(0.998)PS(0.002)PK 145.14 0.00019553 7211500.0 57616.0 41809.0 53852.0 43732.0 50948.0 45519.0 34907.0 38711.0 47650.0 37485.0 True False 56794.3852745196 41712.19382923728 49424.496434731496 46948.197165675396 47951.3388076219 43572.25847997158 36714.31365873726 40509.654381453416 42283.15522325524 43964.23230437713 1.2918316162401198 0.9487756670115758 1.124197872774199 1.067872556960381 1.0906897788102126 0.9910842563634046 0.8350950701141194 0.9214229899658734 0.9617626194520285 1.0 15.424042656433215 -6.898031157685926 3.523436969737928 0.9216354998556128 1.0954952085539267 0.46840149747364446 0.08795931692387787 0.20870490892660948 5.053591103160029 0.03121118830993412 0.02712858450820934 1.2646456144639323e-07 6.898031157685926 0.1738597086983139 GVLS(ph)TR ddPTM_PC-9_Lapatinib_30min_R1 1 GVLSTR 6 0 H0YAQ1;H0YAQ3;E5RJZ9;O75525-2;O75525 H0YAQ1 KHDRBS3 KH domain-containing, RNA-binding, signal transduction-associated protein 3 1 GVLS(0.874)T(0.126)R 87.181 0.039956 6921200.0 25078.0 23217.0 27638.0 23526.0 29505.0 28487.0 27204.0 26530.0 30359.0 25930.0 True False 24720.383121258033 23163.242462948223 25365.710325765212 25256.18052043535 27769.573909061866 27268.677416440405 28612.490009805715 27762.680652526637 26939.6497255573 30411.96595044683 0.8128505457863973 0.7616489674061303 0.8340700619978343 0.8304685255003803 0.9131134091860267 0.8966430338923801 0.9408300027833395 0.9128867465445367 0.8858240131352472 1.0 14.89235146047865 -6.0899987608502615 1.133568340614988 0.9271054435900524 0.7864671585173797 0.7560889868402687 0.03263101360778214 0.23821943007613372 0.6273546855212635 0.012459959783186716 0.022379259352671516 8.128328353742216e-07 6.0899987608502615 -0.14063828507267273 GVMDY(ph)YLK ddPTM_PC-9_AZD4547_30min_R2 1 GVMDYYLK 8 0 O95365 O95365 ZBTB7A Zinc finger and BTB domain-containing protein 7A 1 GVMDY(1)YLK 86.866 0.012740000000000001 121400000.0 50768.0 28299.0 39553.0 48577.0 42682.0 33945.0 19931.0 24600.0 25006.0 20176.0 True False 66911.1679600003 37446.09833289321 39028.50137652891 37378.32315716853 36756.34104494862 31822.413783873315 21704.820388536864 20798.635251763226 26327.766109239205 19469.644381096445 3.436691839372577 1.923306743560789 2.00458213887166 1.9198256745490463 1.8878794252984021 1.6344630215624523 1.114803124478771 1.0682596376519917 1.3522468923367434 1.0 14.248938912589985 -1.5228787452803376 0.3052443590281808 1.0731346131373727 18.80310234604068 0.8304266179120877 0.2789098159033545 22.925424320199042 0.3271177021723857 0.28993166826129996 223.26472141064193 0.029999999999999995 1.5228787452803376 17.729967732903308 up GVNLPGAAVDLPAVSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GVNLPGAAVDLPAVSEK 17 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ; 216.39 1.037e-21 6755200.0 46861.0 55973.0 52289.0 44129.0 48872.0 35990.0 53421.0 40865.0 33711.0 44136.0 False True 54793.64175306132 61529.62952732998 53535.76806713681 41656.59519814832 39295.88243058749 34102.621043225954 48360.576145452855 39792.33705004652 34203.959600053764 52137.50741961623 1.0509447893637842 1.1801413717791205 1.0268187091543715 0.7989755793825202 0.7536969904281 0.6540899772741183 0.9275582692558421 0.7632190148598288 0.6560336558625903 1.0 15.670033991971891 -5.687910543732973 3.315725443528713 0.7793669141491564 1.1142860962357508 0.6224321320712298 0.10551336903694898 0.1413478653682468 3.095573887443549 0.028866523710820106 0.05251144621864919 2.051584722095523e-06 5.687910543732973 0.33491918208659444 GVNLPGAAVDLPAVSEK ddPTM_PC-9_Lapatinib_30min_R1 2 GVNLPGAAVDLPAVSEK 17 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ; 166.79 0.00010548 31366000.0 171662.0 170894.0 174209.0 171168.0 152734.0 149852.0 177448.0 158145.0 142381.0 176838.0 False True 169214.06840104432 170498.30544269588 159886.20848618718 183756.26571970963 143750.48640659745 143443.1792820736 186635.3891802678 165492.9940367064 126344.55244160128 207404.21267817632 0.8158661109917249 0.8220580635324589 0.7708918079416179 0.8859813566315522 0.6930933781448853 0.6916116959719165 0.8998630585670169 0.7979249403843959 0.609170618138055 1.0 17.662085672098996 -6.250639318905488 24.845314232442664 0.7732195353149534 0.8198101225675599 0.030939272729250344 0.10717399546787702 2642.8151254138406 6079739.968309681 0.030978257886934535 0.039568078081305885 5.615141193048388e-07 6.250639318905488 0.04659058725260656 GVNTDSGSVCR ddPTM_PC-9_Lapatinib_30min_R1 1 GVNTDSGSVCR 11 0 A0A494C194;K7ES25;A0A494C165;P12955-3;P12955;V9GYE4;P12955-2 A0A494C194 PEPD Xaa-Pro dipeptidase 0 94.363 0.030705 916840.0 11941.0 10329.0 10551.0 9142.6 10092.0 9944.7 9383.6 9055.3 10130.0 7374.2 False True 11770.719150288794 10305.083835111873 9683.5375080378 9814.977302819534 9498.408401635395 9519.388363227969 9869.436893692577 9476.042295997913 8989.052726370948 8648.820644496138 1.3609623362671237 1.191501623018363 1.119636758128419 1.1348341821685832 1.0982316308848319 1.1006573907028394 1.1411309471393887 1.0956456013489186 1.039338552140207 1.0 13.078287704540154 -1.5228787470645013 0.7148959759002289 1.086171541754005 38.98773683678664 0.8367132870337846 0.037368380779635 118.28877621239188 0.591034995805471 0.014229610952033818 7183.803001984685 0.029999999876754335 1.5228787470645013 37.90156529503263 GVNTFS(ph)PEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GVNTFSPEGR 10 0 P28066 P28066 PSMA5 Proteasome subunit alpha type-5 1 GVNT(0.019)FS(0.981)PEGR;GVNT(0.008)FS(0.992)PEGR 152.96 7.0208e-09 0.0 170601.0 169142.0 178813.0 191797.0 216281.0 213091.0 195106.0 202558.0 161283.0 140440.0 True False 199480.37977665834 185933.2999394641 183076.58007207856 181051.23590426397 173902.2906361491 201916.1328347336 176624.14723488328 197241.06712794135 163641.4587575411 165900.66027757185 1.2024085946547987 1.1207508133383872 1.1035313528334927 1.0913231785897861 1.0482314557711196 1.2170905920259962 1.0646380004719074 1.1889106818377528 0.9863822029625993 1.0 17.339960102606916 -8.277573830730908 24.82208740518374 0.9931910528992594 1.1252073129450457 0.49862085673269807 0.05457580627714783 699.5072010268915 1076147.0753311755 0.049744401168765884 0.01300880972592622 5.277474812703001e-09 8.277573830730908 0.13201626004578637 GVNTFS(ph)PEGR ddPTM_PC-9_Lapatinib_30min_R1 3 GVNTFSPEGR 10 0 P28066 P28066 PSMA5 Proteasome subunit alpha type-5 1 GVNT(0.03)FS(0.97)PEGR;GVNT(0.001)FS(0.999)PEGR;GVNT(0.001)FS(0.999)PEGR 137.4 0.00011605 116038000.0 361239.0 327330.0 386918.0 324855.0 352294.0 381722.0 353283.0 282698.0 415788.0 298097.0 True False 356087.6656168808 326572.0874960956 355107.0955866723 348745.9203845119 331572.7595566529 365396.6398974436 371574.2651130055 295833.1811197886 368957.576998255 349622.6692607149 1.0184913534635391 0.9340701167536983 1.0156867011442774 0.9974922996896713 0.9483731711612724 1.0451171277597162 1.062786534690979 0.8461498842318623 1.0553022141797161 1.0 18.415439205527363 -3.6956088961202784 13.242600030161277 0.98944671859107 1.0161697287339153 0.0 0.0630957106875362 0.0 0.0 0.013758087871675914 0.0 0.00020155385259621397 3.6956088961202784 0.026723010142845283 GVNTFSPEGR ddPTM_PC-9_Lapatinib_30min_R1 2 GVNTFSPEGR 10 0 P28066 P28066 PSMA5 Proteasome subunit alpha type-5 0 ; 113.93 0.0057616 10908000.0 36069.0 35342.0 37015.0 36050.0 41629.0 37307.0 34473.0 32822.0 35963.0 29621.0 False True 35554.649445755495 35260.167770405984 33971.76958203197 38701.23725927463 39180.464065762964 35711.46657686461 36257.84326231555 34347.029942601956 31912.46823282116 34740.95038249848 1.0234218999278424 1.0149453996563396 0.9778595348717346 1.1139947765726994 1.1277890683583887 1.0279357986376518 1.043662964401263 0.9886612071472008 0.918583627720725 1.0 15.084349600879364 -7.86255980443493 3.2706762636378324 0.957404285971765 1.0486412805971796 0.385040992273491 0.046008201193005784 0.27020136669547085 5.611146276846977 0.03162695548832451 0.013646691546343492 1.3722719795570421e-08 7.86255980443493 0.09123699462541468 GVPAGNS(ph)DTEGGQPGR ddPTM_PC-9_AZD4547_30min_R2 1 GVPAGNSDTEGGQPGR 16 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-3;Q9UKV3-2;G3V3B0;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 GVPAGNS(0.82)DT(0.18)EGGQPGR 182.28 1.3551e-06 15625000.0 3271.6 3476.8 5789.0 6756.6 7065.9 4439.2 3813.5 7376.0 4673.4 4044.6 True False 4311.900746492614 4600.607607470338 5712.2340775345965 5198.970258429403 6084.921751312084 4161.616122238047 4152.894112271604 6236.208683618112 4920.426383064806 3902.9997850804257 1.1047658170454557 1.178736320984844 1.463549677704348 1.332044720653827 1.5590371730411707 1.0662609150393003 1.0640262210995814 1.597798879584004 1.2606781076118905 1.0 11.930367667996622 -5.018589506154811 20.060812180842017 1.309721491712457 1.123257235394194 0.08649561709843323 0.19688121669170783 112.34117302589964 121248.49784039608 0.0497645813517657 0.1389784789815613 9.58099235979863e-06 5.018589506154811 -0.18646425631826302 GVPAGNS(ph)DTEGGQPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GVPAGNSDTEGGQPGR 16 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-3;Q9UKV3-2;G3V3B0;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 GVPAGNS(0.808)DT(0.192)EGGQPGR;GVPAGNS(0.987)DT(0.013)EGGQPGR;GVPAGNS(0.97)DT(0.03)EGGQPGR 139.12 4.0716e-06 18970500.0 139598.0 183986.0 160728.0 160489.0 240012.0 195474.0 137612.2 186474.0 198095.4 176498.4 True False 163229.18421382064 202250.91415888612 164560.36508433416 151497.3216423582 192983.3715405586 185222.9993276898 124576.5761899492 181579.255085535 200992.170465323 208496.16275943405 0.7828881934971479 0.9700462180315818 0.7892728715310043 0.7266192319191891 0.9255967543308011 0.888376058706667 0.5975005704718293 0.8708997455029608 0.9640089669047326 1.0 17.669661306457456 -8.209414130401075 3.8501218010590725 0.9873316904585704 0.8162940601295755 0.30854574308616667 0.1000201286831748 0.28460724720603797 8.363183342387266 0.08304664988122204 0.026451614331682857 6.174273588289383e-09 8.209414130401075 -0.17103763032899488 GVPAGNS(ph)DTEGGQPGR ddPTM_PC-9_Lapatinib_30min_R1 2 GVPAGNSDTEGGQPGR 16 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-3;Q9UKV3-2;G3V3B0;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 GVPAGNS(0.975)DT(0.025)EGGQPGR;GVPAGNS(0.856)DT(0.144)EGGQPGR 174.35 9.5616e-07 9135700.0 18204.5 25833.5 46825.5 20897.5 25342.1 34889.3 22125.4 20745.0 44347.7 16819.4 True False 17944.90049170357 25773.684117955512 42975.688141657134 22434.371862016404 23851.527502485576 33397.16596993064 23270.944951586367 21708.88843334584 39352.79502401585 19726.61087955825 0.9096798533345136 1.3065439509765742 2.1785641945312966 1.1372643785083263 1.2091041714216495 1.6930006970705005 1.1796727321113705 1.1004874869733314 1.9949090730428147 1.0 14.26785549540583 GVPAGNS(ph)DTEGGQPGRK ddPTM_PC-9_AZD4547_30min_R2 1 GVPAGNSDTEGGQPGRK 17 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-3;Q9UKV3-2;G3V3B0;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 GVPAGNS(0.897)DT(0.103)EGGQPGRK 52.498000000000005 0.030943000000000002 31233000.0 2779.6 6816.7 13027.0 25283.0 16705.0 16214.0 10314.0 19484.0 10993.0 10556.0 True False 3663.4549807283506 9020.06496716609 12854.253468309416 19454.394968456098 14385.799099289328 15200.1360168426 11231.926019134478 16473.195497778644 11574.0675373457 10186.437652996343 0.35964044600525724 0.8854974893517201 1.2618988017394221 1.9098330182910983 1.4122502477652472 1.4921934963565477 1.102635327653589 1.617169422612924 1.1362232736918765 1.0 13.314361987588034 -4.993847277268234 2.136112401231354 1.408310754661715 0.29945164050292167 0.6094770287697281 0.25519865748814985 0.2747303483462413 1.968296885707737 0.06803641896211132 0.49849149721858754 1.0142679975584313e-05 4.993847277268234 -1.1088591141587933 GVPAGNS(ph)DTEGGQPGRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GVPAGNSDTEGGQPGRK 17 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-3;Q9UKV3-2;G3V3B0;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 GVPAGNS(0.986)DT(0.014)EGGQPGRK;GVPAGNS(0.969)DT(0.031)EGGQPGRK 61.648 0.014426 33863000.0 18186.8 18477.4 23006.0 22401.9 29956.0 29157.0 20451.3 25525.0 29681.0 19465.7 True False 21265.46603432651 20311.714159117568 23554.55029074086 21146.794170939727 24086.336840945296 27627.955592034992 18514.004809410144 24854.99579597304 30115.028474064697 22994.677319603594 0.9247994976731905 0.8833224261773517 1.0243479377142621 0.9196386571126834 1.0474744440275765 1.2014935112171112 0.8051430577643482 1.0809021344597636 1.3096521449505538 1.0 14.489012332315175 -5.793612536192675 0.5021942837794684 1.0950680527454006 0.8606626242609393 0.20489820147432336 0.1278875721848392 3.1694420655855167 1.236107777977675 0.09912873548483478 0.3960895904142964 1.6083755549225681e-06 5.793612536192675 -0.23440542848446133 GVPAGNS(ph)DTEGGQPGRK ddPTM_PC-9_Lapatinib_30min_R1 2 GVPAGNSDTEGGQPGRK 17 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-3;Q9UKV3-2;G3V3B0;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 GVPAGNS(0.993)DT(0.007)EGGQPGRK;GVPAGNS(0.998)DT(0.002)EGGQPGRK 90.44200000000001 0.0010935 35889000.0 61892.0 51126.0 62685.0 37374.0 46057.0 47028.0 40351.0 43250.0 49211.0 34864.0 True False 61009.408730397234 51007.62088817207 57531.28127109749 40122.608636009136 43348.017811545935 45016.72206762239 42440.17734104066 45259.5528918876 43668.338965196504 40890.195946640124 1.4920302365391396 1.2474291136861935 1.406970055760389 0.9812280843155495 1.0601078524571796 1.1009172498553736 1.037905941962792 1.106855857353907 1.0679415433025006 1.0 15.3194673558539 -5.75722765663147 24.999999991241204 1.0571106768917518 1.3686718001174942 0.8353866218653218 0.06729965173832463 39.781781304033835 236133.15329141536 0.017521194974788806 0.029015745421145347 1.7489296615231231e-06 5.75722765663147 0.3115611232257425 GVPAGNSDT(ph)EGGQPGR ddPTM_PC-9_AZD4547_30min_R2 2 GVPAGNSDTEGGQPGR 16 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-3;Q9UKV3-2;G3V3B0;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 GVPAGNS(0.25)DT(0.75)EGGQPGR;GVPAGNS(0.027)DT(0.973)EGGQPGR 159.4 0.00012732 7391200.0 119202.2 95101.9 89407.7 118789.0 120247.3 106629.4 110099.7 103573.3 140648.4 142570.2 True False 157106.02004021316 125841.72935598344 88222.09548004657 91404.03132175506 103553.03801448514 99961.84676170698 119898.36000861914 87568.42636266048 148082.78728460052 137578.86069299153 1.1419343004358544 0.9146879740253148 0.6412474637140293 0.6643755505849404 0.7526813166854512 0.7265785329097378 0.8714882461206989 0.6364962314818859 1.0763484051161654 1.0 17.06989928810851 -9.960001958181671 7.828453817115262 1.000000258964665 0.808384118957233 0.08035418539632744 0.1692207888909457 0.0 0.0 0.16473019514691936 0.0399529408423152 1.0964732522658039e-10 9.960001958181671 -0.191616140007432 GVPAGNSDT(ph)EGGQPGR ddPTM_PC-9_Lapatinib_30min_R1 2 GVPAGNSDTEGGQPGR 16 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-3;Q9UKV3-2;G3V3B0;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 GVPAGNS(0.41)DT(0.59)EGGQPGR;GVPAGNS(0.33)DT(0.67)EGGQPGR 201.75 3.3518e-12 39667000.0 11274.4 10504.2 25565.0 9046.6 13177.8 14555.5 10820.1 8014.299999999999 17545.800000000003 8456.0 True False 11113.624988528261 10479.878170276128 23463.14438375381 9711.917142572918 12402.707712551619 13932.995195527725 11380.311834844095 8386.673635640565 15569.607238534993 9917.608333088245 1.1205952700763278 1.0566940958246935 2.3658067142532153 0.979260000636537 1.2505744627131832 1.4048745148608957 1.147485507859371 0.8456346887242964 1.5698953533575137 1.0 13.275776536120675 -6.693597863415308 1.1836178175654823 1.1462790861466003 1.417679693290596 0.058814933743168374 0.40345494678637595 1.4310888848201302 4.245266216458801 0.20271055262207832 0.1950893990836387 2.0248932683087974e-07 6.693597863415308 0.2714006071439956 GVPEKS(ph)PVLEK ddPTM_PC-9_AZD4547_30min_R2 3 GVPEKSPVLEK 11 1 E9PDI4;O00515;A0A0J9YYF6 E9PDI4 LAD1 Ladinin-1 1 GVPEKS(1)PVLEK;GVPEKS(1)PVLEK;GVPEKS(1)PVLEK 105.58 0.012261 190573000.0 407950.0 396882.0 533066.0 599212.0 539202.0 480495.0 475339.0 544714.0 402438.0 534642.0 True False 537669.6141128689 525166.3450494828 525997.1965408631 461072.9311331138 464343.1096040102 450449.57169191976 517643.2501463403 460540.9675824783 423710.0510865393 515924.3463123594 1.042148171444005 1.0179134766621925 1.0195238900829178 0.8936832200858447 0.9000217045831754 0.8730922952397389 1.003331697459651 0.892652131798506 0.8212639200205718 1.0 18.97680000287223 -5.7543811364731 23.178846148190186 0.9092180243984429 1.025667129153771 0.5034429489024739 0.05206684071251844 53.51224880525876 175724.98346262542 0.014125976639820815 0.023750225853016668 1.7604304160321323e-06 5.7543811364731 0.11644910475532799 GVPEKS(ph)PVLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GVPEKSPVLEK 11 1 E9PDI4;O00515;A0A0J9YYF6 E9PDI4 LAD1 Ladinin-1 1 GVPEKS(1)PVLEK;GVPEKS(1)PVLEK;GVPEKS(1)PVLEK 61.958 0.026948000000000003 218921100.0 268797.0 287879.0 294923.0 343345.0 377891.0 347383.0 358449.0 368161.0 305445.0 288844.0 True False 314299.0231172536 316457.72459396906 301955.08282170614 324108.49278950825 303845.9712632411 329165.62394717894 324494.1157739732 358497.16384882457 309911.55527983274 341209.13071215444 0.9211330964715527 0.9274597193031573 0.884956044967146 0.9498822382421168 0.8904977736940074 0.9647034452453283 0.9510124043184468 1.050666971017415 0.9082745078743966 1.0 18.380296727942053 -7.02863556456387 2.3190665273620668 0.9827106727758481 0.9159315112619606 0.3727917444009431 0.03834315532746828 0.3072900760988032 3.2964391205463106 0.01533959655771141 0.01188795542356527 9.361909432655397e-08 7.02863556456387 -0.06677916151388752 GVPEKS(ph)PVLEK ddPTM_PC-9_Lapatinib_30min_R1 4 GVPEKSPVLEK 11 1 E9PDI4;O00515;A0A0J9YYF6 E9PDI4 LAD1 Ladinin-1 1 GVPEKS(1)PVLEK;GVPEKS(1)PVLEK;GVPEKS(1)PVLEK;GVPEKS(1)PVLEK 116.96 0.0058362 140063000.0 201479.0 193071.0 215686.0 200006.0 211698.0 167997.0 157898.0 163231.0 191172.0 135075.0 True False 198605.8725132762 192623.95596174692 197953.12965203694 214715.1084404572 199246.3398542815 160812.15993013434 166073.1858391523 170815.30816406256 169640.19622959383 158422.53377387632 1.2536466106315114 1.2158873575187723 1.2495263453782681 1.3553318667843668 1.257689389936629 1.0150838779012892 1.0482927010635754 1.0782260837203563 1.0708085029856231 1.0 17.273418031140153 -6.754601478457962 24.909046669806365 1.047734510659064 1.267610619419994 0.8879733496112155 0.039746554719391175 51.49279175614421 187577.22350245804 0.014195481313228613 0.013894248589480188 1.7595374773373549e-07 6.754601478457962 0.21987610876093 GVPGCCYS(ph)SLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GVPGCCYSSLPR 12 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 GVPGCCY(0.036)S(0.482)S(0.482)LPR;GVPGCCY(0.002)S(0.721)S(0.278)LPR 83.045 0.011451000000000001 26944000.0 33421.0 36083.0 40105.0 48221.0 66047.0 52197.0 41749.0 43866.0 41695.0 43437.0 True False 39078.51520516124 39665.0817757606 41061.25529905946 45519.33370459133 53105.56447235655 49459.697432433066 37794.23248341497 42714.56397986888 42304.71049580972 51311.78425289722 0.7615894823021039 0.7730209025721219 0.8002305103381983 0.8871126655865834 1.0349584456197904 0.9639052344908552 0.7365604808661665 0.8324513481999427 0.824463836363692 1.0 15.647002572454555 -5.685290189544288 3.8075296936306064 0.8922201052104556 0.7717976791134308 0.3018225765843908 0.08347461354415575 0.3280214853621858 9.24716775122686 0.02578749154039765 0.04606790709520633 2.0640005584255703e-06 5.685290189544288 -0.1204224260970248 GVPGCCYSS(ph)LPR ddPTM_PC-9_AZD4547_30min_R2 3 GVPGCCYSSLPR 12 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 GVPGCCY(0.003)S(0.393)S(0.604)LPR;GVPGCCYS(0.052)S(0.948)LPR;GVPGCCY(0.002)S(0.22)S(0.777)LPR 131.79 0.00010607 56772000.0 85364.0 90848.0 112240.0 162032.0 151105.0 128615.0 114786.0 127912.0 109072.0 110378.0 True False 112507.97631849723 120212.83937053195 110751.62426368687 124678.02576944511 130126.67901215861 120572.68371815768 125001.73163005328 108146.13952534705 114837.3232450988 106513.69981644825 1.0562770471064167 1.128613873874356 1.0397875996659744 1.1705351141148874 1.2216895970790789 1.131992259455233 1.173574214823679 1.0153261008838481 1.0781460360779354 1.0 16.700679476588668 -7.768914347721258 24.999696263863136 1.0350520276692858 1.1330779845908419 0.4224389134021733 0.053844636267844234 186.35329333338234 623238.1746160784 0.030236728698261786 0.014978716250707977 1.7024942440280033e-08 7.768914347721258 0.09802595692155602 GVPGCCYSS(ph)LPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GVPGCCYSSLPR 12 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 GVPGCCYS(0.137)S(0.863)LPR 81.625 0.012999 17768000.0 17053.0 17441.0 17715.0 17145.0 24332.0 17278.0 21319.0 18413.0 16659.0 16202.0 True False 19939.73608789727 19172.427216446526 18137.392784511634 16184.421234839976 19564.319268723488 16371.911263819338 19299.509983806158 17929.67826018615 16902.606359268346 19139.29434503858 1.0418219046339179 1.0017311438348058 0.9476521159837502 0.8456122228474643 1.022206927592139 0.8554083013025702 1.0083710316524346 0.9367993373712863 0.8831363400631307 1.0 14.224250019003453 -5.14053029491577 2.8705420452072214 0.934156014206369 1.0358910922062115 0.2602314696578897 0.05867648833052094 0.35348975485727896 5.380429717746951 0.01467734381964079 0.05526758282502725 7.235519279818767e-06 5.14053029491577 0.1017350779998425 GVPGCCYSS(ph)LPR ddPTM_PC-9_Lapatinib_30min_R1 4 GVPGCCYSSLPR 12 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 GVPGCCYS(0.17)S(0.83)LPR;GVPGCCYS(0.205)S(0.795)LPR;GVPGCCYS(0.214)S(0.786)LPR;GVPGCCYS(0.011)S(0.989)LPR 146.5 0.00012382 85003000.0 244974.0 220182.0 223265.0 215411.0 201763.0 218911.0 172972.0 169876.0 203562.0 169318.0 True False 241480.62583727099 219672.18210694197 204909.0135278231 231253.04353003125 189895.69702132032 209548.68683646532 181927.64380150416 177769.05912282725 180634.70395711 198584.39069794613 1.2160101052684023 1.1061905789013957 1.0318485395939148 1.164507657008024 0.9562468447490335 1.05521227574828 0.9161225772181789 0.8951814314208626 0.9096117943724075 1.0 17.599392701796106 -6.286461633170505 0.6677694262493938 0.918483307531985 1.1671340347045593 0.6454689574417278 0.06269584281244463 0.526506322865357 0.5030770438724195 0.040505618737532265 0.07340435443511482 5.170569342547284e-07 6.286461633170505 0.2486507271725743 GVPHPEDDHS(ph)QVEGPESLR ddPTM_PC-9_Lapatinib_30min_R1 1 GVPHPEDDHSQVEGPESLR 19 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 GVPHPEDDHS(0.999)QVEGPES(0.001)LR 117.4 0.00021008 0.0 21569.0 24605.0 23805.0 26633.0 23945.0 27535.0 22279.0 23120.0 25738.0 24404.0 True False 21261.422104729823 24548.02863422669 21847.844789957337 28591.679665083535 22536.6021776813 26357.392237220018 23432.497608015798 24194.239603709622 22839.115406844572 28622.198883714 0.7428297941437179 0.8576569792544657 0.7633181810636057 0.9989337220821343 0.7873819292935107 0.9208723740724667 0.8186826491988658 0.8452963275814604 0.7979511112907542 1.0 14.804846890075623 -11.910627463028566 2.209652366308481 2.1441694616995726 0.8409091575165556 0.3116729942519939 0.07246386442607455 3661556.8905705744 449975.0758926109 20916664.69159979 0.017036299078790767 1.2284925778853532e-12 11.910627463028566 -1.3032603041830169 GVPHPEDDHSQVEGPES(ph)LR ddPTM_PC-9_AZD4547_30min_R2 2 GVPHPEDDHSQVEGPESLR 19 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 GVPHPEDDHS(0.04)QVEGPES(0.96)LR;GVPHPEDDHSQVEGPES(1)LR 65.915 0.012308 3085200.0 70261.0 60708.0 101839.0 126981.0 116546.0 114419.0 97150.0 117954.0 98836.0 112295.0 True False 92602.53648041263 80330.67379035598 100488.54831957951 97707.49228689348 100365.59963039645 107264.36184230373 105796.16179551225 99726.91961327152 104060.26918230686 108363.5862299377 0.854554003813776 0.7413068963950822 0.9273276366689445 0.9016635171114311 0.9261930425357994 0.9898561460922719 0.9763073138888407 0.9202991805906094 0.9602881632350225 1.0 16.725520519033758 -5.537726847715386 1.581348930098201 0.9575101416753027 0.7957764371313224 0.6649932129580158 0.04202398723557275 0.24011453836106744 1.1465585100662123 0.012532137889172377 0.037819230291071704 2.899166463626633e-06 5.537726847715386 -0.16173370454398028 GVPHPEDDHSQVEGPES(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 1 GVPHPEDDHSQVEGPESLR 19 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 GVPHPEDDHS(0.02)QVEGPES(0.98)LR 96.881 0.00035965 3312400.0 26827.0 23811.0 37086.0 31645.0 26410.0 32893.0 33372.0 29050.0 36344.0 33332.0 True False 26444.44206053073 23755.86709244347 34036.93223609992 33972.278864625376 24856.615724057763 31486.24306732807 35099.838869549916 30399.769052238957 32250.556000713295 39093.39178790177 0.6764427656725988 0.6076696343292269 0.870656923829089 0.8690031054081825 0.6358265319856472 0.8054108796226813 0.8978458318475263 0.7776191233846016 0.8249618292443449 1.0 15.254637139497826 -12.011310096383397 0.03632965246208314 2.00478987564464 2.4098712951964407e-12 0.4675210995264062 0.08620847056498153 598.9419290464641 2.656114862211624 101.73458387681926 51.67653623176726 9.742937208692337e-13 12.011310096383397 -2.00478987564223 GVPHPEDDHSQVEGPESLR ddPTM_PC-9_AZD4547_30min_R2 1 GVPHPEDDHSQVEGPESLR 19 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 0 97.214 0.00025957 2722200.0 5960.0 7158.9 13112.0 12275.0 10583.0 10550.0 11263.0 10356.0 6615.2 7865.7 False True 7855.156024298808 9472.874425080354 12938.126312771392 9445.1883968595 9113.733125877214 9890.306832224582 12265.385180677868 8755.718157205689 6964.865966801535 7590.324237132745 1.0348907080768006 1.2480197326403997 1.7045551558228014 1.2443721904069056 1.2007040596884881 1.3030150653960282 1.6159237467978222 1.1535367770419742 0.9175979509186979 1.0 12.889945799461238 -7.99828779000858 24.93955344124422 0.98438836769897 1.3401631856811134 0.3983325224868408 0.1858000335760472 52.38357101060406 763007.6826750732 0.10591145449988945 0.05029583322032493 1.0039502911151182e-08 7.99828779000858 0.3557748179821434 GVQDSEGSPIS(ph)SLTQK ddPTM_PC-9_AZD4547_30min_R2 1 GVQDSEGSPISSLTQK 16 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 GVQDSEGS(0.033)PIS(0.849)S(0.116)LT(0.002)QK 122.42 5.8469e-05 11294000.0 66042.0 73921.0 76622.0 98480.0 88342.0 87945.0 76190.0 99954.0 78443.0 96121.0 True False 87041.98224106409 97814.51764605822 75605.94221607463 75776.95750083294 76077.2381939192 82445.78524739249 82970.76240041251 84508.40601442031 82589.33683544156 92755.83304695554 0.9383990136447922 1.0545376439726635 0.8151071445587776 0.8169508591710084 0.8201881832639768 0.8888474453747418 0.8945072204613853 0.9110845457195113 0.8903950740610844 1.0 16.501150389512624 -10.348920381897912 15.126625178129252 0.9999999995955952 0.8909198350386168 0.1860416716408937 0.06758036316636447 0.0 0.0 0.07128681116406506 0.017289591302523565 4.47795389841035e-11 10.348920381897912 -0.10908016455697833 GVQDSEGSPIS(ph)SLTQK ddPTM_PC-9_Lapatinib_30min_R1 1 GVQDSEGSPISSLTQK 16 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 GVQDSEGS(0.003)PIS(0.989)S(0.008)LTQK 197.1 6.4959e-12 11025000.0 37278.0 36429.0 45813.0 28811.0 41782.0 38680.0 29069.0 33952.0 39764.0 31372.0 True False 36746.40888405205 36344.65088869107 42046.43198329407 30929.85705067854 39324.46490657258 37025.74656748393 30574.050584290628 35529.53386786977 35285.35958651673 36794.60839943763 0.9986900386365759 0.9877711020630555 1.1427335094001627 0.8406084042234642 1.0687561742652931 1.0062818488387508 0.8309383334749099 0.9656179373392327 0.9589817943831148 1.0 15.167206759819178 -7.064092281353525 24.999630758974224 0.9335322347939169 1.0080921343598335 0.14300561795520073 0.08184205158274026 391.9631166125148 152886.31709490553 0.030227444157496168 0.023414091228313224 8.627951966733556e-08 7.064092281353525 0.07455989956591658 GVQDSEGSPISS(ph)LTQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GVQDSEGSPISSLTQK 16 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 GVQDS(0.002)EGS(0.106)PIS(0.19)S(0.655)LT(0.048)QK 97.235 0.0022158 6639800.0 33383.0 38062.0 37452.0 37119.0 43625.0 28160.0 35441.0 27440.0 24827.0 30010.0 True False 39034.082555695444 41840.543817005215 38344.99771750096 35039.3427714217 35076.99441468283 26683.2400271532 32083.771909380113 26719.729075083247 25190.04790693053 35450.5754409707 1.1010845965164007 1.180250060726787 1.0816466937567715 0.9883998309072938 0.9894619192596766 0.7526884879932026 0.9050282403117348 0.75371778152303 0.7105680963874582 1.0 15.113521425324448 -6.222203558948409 1.1048680953321393 0.8093315806558101 1.1427354410589516 0.6721925834698478 0.08783941695795497 0.2724533080348818 0.6897322107819515 0.036035023608729164 0.05646148680591955 5.995100129744265e-07 6.222203558948409 0.3334038604031415 GVQDSEGSPISS(ph)LTQK ddPTM_PC-9_Lapatinib_30min_R1 1 GVQDSEGSPISSLTQK 16 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 GVQDSEGS(0.046)PIS(0.27)S(0.683)LT(0.001)QK 195.45 8.314e-12 9022700.0 39338.0 41612.0 48034.0 44173.0 40215.0 46377.0 39975.0 37954.0 43975.0 37272.0 True False 38777.03290629429 41515.64997063363 44084.82993660203 47421.62977680829 37849.63276573204 44393.563820067306 42044.70990082277 39717.48139788904 39022.07242272088 43714.415538181805 0.8870536739173598 0.9497015906428466 1.00847350682515 1.0848053026212476 0.8658387010269589 1.015536025668519 0.9618042328416663 0.9085671376115805 0.8926591364040436 1.0 15.41582148984645 -7.637335311568016 6.13881191034792 0.925893660937999 0.971563725154498 0.04982597247363363 0.06467494502228699 0.5534154253743777 27.538290977835185 0.03120149942087089 0.017733067822502724 2.3049668748299446e-08 7.637335311568016 0.045670064216498996 GVQKPAGPS(ph)TSPDGNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GVQKPAGPSTSPDGNSR 17 1 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 GVQKPAGPS(0.642)T(0.314)S(0.044)PDGNSR;GVQKPAGPS(0.722)T(0.247)S(0.031)PDGNSR 81.71300000000001 0.0023222 17456600.0 48790.0 49846.0 52809.0 54706.0 59152.0 51593.0 58739.0 42604.0 52160.0 32169.0 True False 57049.18335357465 54794.38145926232 54068.166839247766 51641.00017924498 47561.59022618496 48887.37225571429 53174.816686467035 41485.690142669315 52922.74132297484 38000.98505033613 1.5012553826698771 1.441920028827717 1.422809613162107 1.358938462012005 1.2515883512804957 1.2864764476751864 1.3993010080141774 1.0917003884956493 1.3926676177702588 1.0 15.213749195706088 -1.5228787713418954 0.034879781361610185 3.969055649697886e-08 3.343273740490617 0.6452968415713711 0.09059970616679877 605.6283418289768 1.6207040212115538 46.046905715582135 128.5132579055105 0.029999998199731415 1.5228787713418954 3.3432737008000606 GVQKPAGPS(ph)TSPDGNSR ddPTM_PC-9_Lapatinib_30min_R1 2 GVQKPAGPSTSPDGNSR 17 1 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 GVQKPAGPS(0.333)T(0.333)S(0.333)PDGNS(0.001)R;GVQKPAGPS(0.452)T(0.452)S(0.071)PDGNS(0.026)R 55.782 0.024100999999999997 19673700.0 44227.0 48207.0 39313.0 38058.0 46672.0 41984.0 44886.0 36562.0 43484.0 39861.0 True False 43596.31486976151 48095.379653329255 36080.836892568506 40856.91227776624 43926.84472068244 40188.44218948412 47209.97745111525 38260.803996143186 38586.37401318008 46750.92073855614 0.9325231285510709 1.0287579130749467 0.7717674074130509 0.8739274357022657 0.9395931465464242 0.8596288918934628 1.009819201532442 0.8183968014257517 0.8253607288071517 1.0 15.512707158065622 -5.231880603673319 24.999429828422084 0.8856016267065712 0.9806405154402138 0.19353142104312582 0.07614276987342555 1118.412114786965 945897.0635934942 0.018878396885338135 0.04993284440257934 5.8629932788912066e-06 5.231880603673319 0.09503888873364263 GVQKPAGPST(ph)SPDGNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GVQKPAGPSTSPDGNSR 17 1 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 GVQKPAGPS(0.124)T(0.438)S(0.438)PDGNSR 141.85 1.4067e-07 0.0 11500.0 10265.0 12696.0 12808.0 13523.0 12701.0 13903.0 13952.0 9313.6 8302.9 True False 13446.722864646605 11284.041360978366 12998.720789848128 12090.409284096257 10873.265225667757 12034.937201167351 12586.007190996628 13585.774783365947 9449.793780399892 9808.15004427977 1.3709744247325104 1.150476013319082 1.3252979135886218 1.232690082177885 1.1085949110259763 1.2270343690537515 1.2832192752125502 1.3851516057596747 0.9634634194764511 1.0 13.259765334090718 -8.277148119520193 24.88742727305838 0.9817316199353874 1.252587611149032 0.6365045369685978 0.08407780366827883 565.6625958944607 896172.4692767388 0.08015243043146827 0.02099482252596375 5.282650521316173e-09 8.277148119520193 0.27085599121364456 GVQKPAGPSTS(ph)PDGNSR ddPTM_PC-9_AZD4547_30min_R2 2 GVQKPAGPSTSPDGNSR 17 1 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 GVQKPAGPS(0.106)T(0.106)S(0.786)PDGNS(0.002)R;GVQKPAGPS(0.19)T(0.19)S(0.619)PDGNSR 142.4 0.00046152 11016200.0 22373.0 21910.0 25717.0 33144.0 32081.0 26592.0 20412.2 26387.0 24268.0 23893.0 True False 29487.148612690806 28991.979026597768 25375.97577681071 25503.162869695432 27627.10690836878 24929.19803625747 22228.84625632894 22309.495462938045 25550.756935896057 23056.5133424632 1.2789075336201983 1.257431190743104 1.1005990107825954 1.1061153302275863 1.1982343773326696 1.0812215041354645 0.9641026778923271 0.9676005704579204 1.1081795654176039 1.0 14.49288674146124 -3.112243930788423 0.28807889251279145 0.9907432082208045 2.037767931833049 0.6769681855772871 0.060285756626749586 13.213122251725604 0.4183061792095067 0.0721236443384853 5.843511973465536 0.0007722467143697193 3.112243930788423 1.0470247236122445 GVQKPAGPSTS(ph)PDGNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GVQKPAGPSTSPDGNSR 17 1 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 GVQKPAGPS(0.021)T(0.041)S(0.938)PDGNSR;GVQKPAGPS(0.075)T(0.228)S(0.696)PDGNSR 178.51 3.7442e-32 2827300.0 24695.0 20702.7 24278.0 28603.0 33688.0 30861.0 24966.0 27584.5 26063.0 24016.0 True False 28875.375751517215 22757.92723662221 24856.879594827715 27000.46664217717 27087.07823133145 29242.59483231446 22601.03974181269 26860.436103193635 26444.122068648252 28369.910689448618 1.017816942309113 0.8021853676503246 0.876170526827655 0.9517289968846897 0.9547819352637482 1.030760905538924 0.7966553010763796 0.9467931146213869 0.9321186223713912 1.0 14.792073988459487 -14.52287874524441 0.2621157049846723 1.519365558090854 0.9140852052098202 0.08336332979611216 0.07486458334678592 526.8274293940297 5.157201833512606 147.55279731091983 0.09808966734326388 3.0000000002481747e-15 14.52287874524441 -0.6052803528810339 GVQKPAGPSTS(ph)PDGNSR ddPTM_PC-9_Lapatinib_30min_R1 1 GVQKPAGPSTSPDGNSR 17 1 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 GVQKPAGPS(0.009)T(0.042)S(0.938)PDGNS(0.011)R 170.16 7.040699999999999e-05 4495400.0 18158.0 14722.0 16974.0 12709.0 16838.0 13951.0 10836.0 9736.8 17201.0 13055.0 True False 17899.063590230617 14687.912113516977 15578.463241534793 13643.662255981164 15847.62194478169 13354.348251369409 11397.035059044792 10189.207273935972 15263.642245439945 15311.539355305951 1.1689917763903996 0.9592707677969121 1.0174328576660285 0.8910705801277379 1.0350116717226063 0.8721754189099014 0.7443428642003487 0.6654593661351937 0.9968718292292794 1.0 13.902331711938198 -6.8829530951483 4.566641337616903 0.8218822055680307 1.0042530002583523 0.3012898842059244 0.11674671963257538 0.2433277839534397 8.615242433794824 0.04132167489159736 0.036375710369361 1.3093233254410144e-07 6.8829530951483 0.18237079469032158 GVQVETIS(ph)PGDGR ddPTM_PC-9_AZD4547_30min_R2 3 GVQVETISPGDGR 13 0 Q1JUQ3;A0A087WTS4;A0A087WV48;A0A087WZM5;P62942 Q1JUQ3 FKBP12-Exin;FKBP1A Peptidyl-prolyl cis-trans isomerase;Peptidyl-prolyl cis-trans isomerase FKBP1A 1 GVQVET(0.001)IS(0.999)PGDGR;GVQVET(0.054)IS(0.946)PGDGR;GVQVET(0.006)IS(0.994)PGDGR 111.07 0.00060623 19380500.0 62974.0 61325.0 87314.0 108036.0 96608.0 85166.0 71799.0 96060.0 70910.0 82552.0 True False 82998.42205942838 81147.10697426321 86156.15931004594 83129.96933956114 83195.64677546489 79840.5565567052 78188.97190690691 81216.13423920218 74658.15783436583 79661.87960687318 1.0418838027551052 1.0186441416486725 1.081523053877484 1.043535123070191 1.0443595755715362 1.0022429416769199 0.9815105078208677 1.019510644739983 0.9371880026281024 1.0 16.281601899767786 -6.845439434503879 2.9475048169666276 0.9863536883234659 1.0469929166458811 0.5983132179151602 0.024034099676748487 0.18484471301446967 3.2434940501387572 0.008846282173374171 0.007835747300576111 1.4274488843215125e-07 6.845439434503879 0.060639228322415195 GVQVETIS(ph)PGDGR ddPTM_PC-9_Lapatinib_30min_R1 4 GVQVETISPGDGR 13 0 Q1JUQ3;A0A087WTS4;A0A087WV48;A0A087WZM5;P62942 Q1JUQ3 FKBP12-Exin;FKBP1A Peptidyl-prolyl cis-trans isomerase;Peptidyl-prolyl cis-trans isomerase FKBP1A 1 GVQVETIS(1)PGDGR;GVQVET(0.013)IS(0.987)PGDGR;GVQVET(0.001)IS(0.999)PGDGR;GVQVET(0.002)IS(0.998)PGDGR 137.73 4.4766000000000005e-05 28274900.0 110815.0 105698.0 117148.0 105348.0 117666.0 108914.0 103790.0 99119.0 113727.0 86477.0 True False 109234.7577790179 105453.26277506568 107516.54364435711 113095.64335062566 110745.11722025661 104256.00211093442 109163.73835162957 103724.43059169932 100917.86766159801 101424.43422664073 1.0770063309884914 1.0397224650957602 1.0600655006278181 1.11507295271576 1.0918978061320814 1.0279180052211712 1.076306110889362 1.0226769454776456 0.995005478029971 1.0 16.630045729254142 -7.919706436019893 2.8268763335595644 0.9980479033395628 1.069514614805308 0.6178999691408178 0.023435306397327063 0.1957472353811632 3.058190580597346 0.017607473816711686 0.006899064591572214 1.203077387258173e-08 7.919706436019893 0.07146671146574524 GVQVETISPGDGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GVQVETISPGDGR 13 0 Q1JUQ3;A0A087WTS4;A0A087WV48;A0A087WZM5;P62942 Q1JUQ3 FKBP12-Exin;FKBP1A Peptidyl-prolyl cis-trans isomerase;Peptidyl-prolyl cis-trans isomerase FKBP1A 0 108.37 0.004168 3870600.0 9706.6 12225.0 14374.0 17682.0 17588.0 17754.0 16168.0 17961.0 14255.0 16081.0 False True 11349.735665911207 13438.61720778963 14716.730673698563 16691.334865817465 14141.757656514412 16822.94898586924 14636.449993816695 17489.542781252552 14463.452407189536 18996.358002874033 0.5974690340218931 0.7074312458080886 0.774713272484758 0.8786597337917178 0.7444457329333787 0.8855881208031576 0.7704871634658754 0.9206787310813205 0.7613802816835366 1.0 14.213435229956259 -3.899434005172932 0.605098383306016 0.8557324438919034 4.467339167339697e-23 0.5580539412342989 0.07390395308848118 6.899948812412944 0.8633992973325488 0.03192332905793104 5.229412927626829 0.0001260567177496886 3.899434005172932 -0.8557324438919034 GVQVPAS(ph)PDTVPQPSLR ddPTM_PC-9_AZD4547_30min_R2 2 GVQVPASPDTVPQPSLR 17 0 F2Z2B6;F2Z3N8;Q92613 F2Z2B6 JADE3 Protein Jade-3 1 GVQVPAS(0.863)PDT(0.133)VPQPS(0.004)LR;GVQVPAS(0.994)PDT(0.006)VPQPSLR 99.74700000000001 0.0012274 11849400.0 31942.0 31504.0 46745.0 64915.0 48737.0 49071.0 37642.0 50508.0 46181.0 46942.0 True False 42098.89156512629 41687.051905702196 46125.13075735961 49949.8496767523 41970.70881185653 46002.5826127102 40992.06507778356 42703.14915837627 48622.03337961995 45298.57486803281 0.9293645923248561 0.920272923091908 1.0182468409157415 1.1026803784063832 0.9265348619493821 1.0155414987497589 0.9049305678424697 0.9427040317003851 1.0733678381995302 1.0 15.467178042113154 -5.2512362967050015 24.17276962542522 0.9944431924027607 0.9248187409234643 0.1978574284286747 0.058591246088669315 785.6891135154391 1861409.3872820877 0.015390376452003392 0.03967681455201762 5.60742796634863e-06 5.2512362967050015 -0.06962445147929641 GVQVPASPDT(ph)VPQPSLR ddPTM_PC-9_Lapatinib_30min_R1 2 GVQVPASPDTVPQPSLR 17 0 F2Z2B6;F2Z3N8;Q92613 F2Z2B6 JADE3 Protein Jade-3 1 GVQVPAS(0.031)PDT(0.969)VPQPSLR;GVQVPAS(0.404)PDT(0.596)VPQPSLR 178.99 7.2786e-06 9284000.0 52227.0 43926.0 58068.0 50792.0 49090.0 54358.0 49722.0 41309.0 56093.0 47104.0 True False 51482.23340274118 43824.29204580537 53293.873188962105 54527.41311714498 46202.62271465334 52033.23505468698 52296.36186838548 43228.366945918686 49775.21565452377 55245.86363786527 0.9318748954710064 0.7932592444037456 0.9646672108938616 0.9869953970594122 0.8363091763305563 0.9418485227376123 0.9466113555792398 0.7824724621788726 0.9009763333739985 1.0 15.753578830795005 -6.389393465867519 0.005592252514862467 1.8013054249074976 1.209515040520752e-07 0.04563173891631278 0.07260215121235977 55809.29245592347 95.94179790229289 15142.26514092185 15759.637315738035 4.0794962113354057e-07 6.389393465867519 -1.8013053039559934 GVQVPVS(ph)PGTIPQPVAR ddPTM_PC-9_AZD4547_30min_R2 2 GVQVPVSPGTIPQPVAR 17 0 Q6IE81-2;Q6IE81;Q6IE81-3;D6RCS1;D6RC05;D6RBB3;D6RFK0;D6RGE7 Q6IE81-2 JADE1 Protein Jade-1 1 GVQVPVS(0.907)PGT(0.093)IPQPVAR;GVQVPVS(0.5)PGT(0.5)IPQPVAR 221.34 5.2396000000000007e-23 17071900.0 95579.0 91199.0 128548.0 174594.0 144612.0 129841.0 107713.0 156790.0 99460.0 129791.0 True False 125971.13383329788 120677.29325635289 126843.36952822875 134344.05075041048 124535.11998482027 121722.02174434833 117299.24833226998 132561.70817577044 104717.25254838553 125247.05659530582 1.005781191651726 0.963514006131748 1.0127453129543864 1.072632398735713 0.9943157417839691 0.9718553477679921 0.9365429537500707 1.058401784275853 0.8360855368181982 1.0 16.934417173783423 -6.708158117257693 3.686111285222814 0.9621283493110188 1.012183967999221 0.15835542948958314 0.057832166616280815 0.4651417157130936 12.8967005041011 0.019639718774653054 0.018953383523344313 1.958131630201782e-07 6.708158117257693 0.0500556186882023 GVQVPVS(ph)PGTIPQPVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GVQVPVSPGTIPQPVAR 17 0 Q6IE81-2;Q6IE81;Q6IE81-3;D6RCS1;D6RC05;D6RBB3;D6RFK0;D6RGE7 Q6IE81-2 JADE1 Protein Jade-1 1 GVQVPVS(0.5)PGT(0.5)IPQPVAR;GVQVPVS(0.999)PGT(0.001)IPQPVAR 226.39 5.080199999999999e-29 11962400.0 50045.0 48203.0 57407.0 60667.0 68313.0 60578.0 58425.0 61911.0 55273.0 45684.0 True False 58516.630066194724 52988.27527747101 58775.80059725988 57268.02467506773 54927.558038973664 57401.18303852576 52890.56103963016 60285.90185012676 56081.263058757446 53966.14756565497 1.0843210550651898 0.9818798944839581 1.089123519994706 1.0611842286017492 1.0178150658641891 1.063651671053446 0.9800692364650219 1.1171059000789931 1.0391933756347762 1.0 15.719767082122216 -8.553060066490369 21.508677091440855 0.9999999956386609 1.0479835756864901 0.1071609797449723 0.04254731804782618 3606.2892804597973 2570017.256164737 0.03867039223281195 0.009984652420004708 2.798594224321187e-09 8.553060066490369 0.04798358004782921 GVQVPVS(ph)PGTIPQPVAR ddPTM_PC-9_Lapatinib_30min_R1 1 GVQVPVSPGTIPQPVAR 17 0 Q6IE81-2;Q6IE81;Q6IE81-3;D6RCS1;D6RC05;D6RBB3;D6RFK0;D6RGE7 Q6IE81-2 JADE1 Protein Jade-1 1 GVQVPVS(0.743)PGT(0.257)IPQPVAR 248.67 1.5995999999999998e-47 6505200.0 36854.0 37387.0 39027.0 31672.0 34810.0 27326.0 32307.0 34071.0 36702.0 31949.0 True False 36328.45520180413 37300.432698550416 35818.35070857657 34001.264534694776 32762.544239093168 26157.330680017218 33979.69838063496 35654.06304230063 32568.23427080616 37471.34208063348 0.9694997079002399 0.9954389308577394 0.9558865180622597 0.9073938281027792 0.8743360237429556 0.6980622851386007 0.9068182908291633 0.9515021630551075 0.8691504617241499 1.0 15.193500029978688 -5.800931991546305 2.419058078465088 0.8738216832665294 0.9812429246899861 0.22807627722259116 0.07380394085977257 0.4070978041310186 4.857892721682579 0.023047183476201407 0.04114709751187454 1.5814956745938067e-06 5.800931991546305 0.10742124142345666 GVQVPVSPGT(ph)IPQPVAR ddPTM_PC-9_Lapatinib_30min_R1 1 GVQVPVSPGTIPQPVAR 17 0 Q6IE81-2;Q6IE81;Q6IE81-3;D6RCS1;D6RC05;D6RBB3;D6RFK0;D6RGE7 Q6IE81-2 JADE1 Protein Jade-1 1 GVQVPVS(0.226)PGT(0.774)IPQPVAR 252.79 4.1376e-57 8512900.0 41878.0 40100.0 46616.0 32702.0 31918.0 38722.0 37164.0 33513.0 40870.0 29638.0 True False 41280.81204051539 40007.15091373665 42783.41242296374 35107.01417067403 30040.645993202415 37065.95032539072 39088.17007515141 35070.13632522148 36266.79021982038 34760.88880984741 1.1875649171784395 1.1509242796577464 1.2307916709783215 1.0099573219407603 0.8642082242929359 1.0663119268368737 1.1244870719208457 1.0088964214081448 1.0433217176410736 1.0 15.085177350803187 -5.769318971053128 24.982508514243722 1.0173104642535096 1.1858766934212464 0.6011903266737962 0.06455327885739474 125.9798828908221 399424.41928775614 0.019591523881458035 0.029664947008781695 1.7009088034588263e-06 5.769318971053128 0.16856622916773678 GVS(ph)CFR ddPTM_PC-9_AZD4547_30min_R2 1 GVSCFR 6 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 GVS(1)CFR 94.006 0.034276 8073100.0 20073.0 11812.0 23055.0 37214.0 28301.0 29484.0 24484.0 19469.0 18941.0 27984.0 True False 26455.796455662752 15629.998003750472 22749.2756361306 28634.887250568605 24371.894660819355 27640.360819081485 26663.028568207155 16460.513403112924 19942.182591182114 27004.288677666693 0.9796886995043288 0.5787968789074944 0.8424319524826028 1.060382948514784 0.9025194091105831 1.0235544860672758 0.9873627439873367 0.6095518234007856 0.738482054803201 1.0 14.720900926183418 -10.666104195888773 4.53360559837859 1.0000175185600917 0.8580268597873953 0.06609773759905357 0.1600311626861908 37111111.123860896 87310415.62184007 3987.261602382109 0.041087992155895 2.1572267854258806e-11 10.666104195888773 -0.14199065877269634 GVS(ph)CFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GVSCFR 6 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 GVS(1)CFR;GVS(1)CFR 99.375 0.0351 8245700.0 21625.8 24341.0 32036.0 36379.0 38946.0 33721.0 34599.0 34255.0 34096.0 25898.0 True False 25286.620810980425 26757.41361593517 32799.85973720655 34340.80257230932 31314.81087620027 31952.611397572193 31321.532244932216 33355.8425461726 34594.58949670531 30593.102391544788 0.8265464707485518 0.8746224319940265 1.0721325126631047 1.1225014754240914 1.0235905621933572 1.0444384158437996 1.0238102642897946 1.0903059820239536 1.1307970356829988 1.0 14.90091879497604 -5.208901622588743 4.252728371037975 1.0657186902215707 0.839898658314659 0.812142233647642 0.041122743130502244 0.08583891928311531 3.2954905967639303 0.010941807543925082 0.031027604196400625 6.1815641052943735e-06 5.208901622588743 -0.2258200319069117 GVS(ph)CFR ddPTM_PC-9_Lapatinib_30min_R1 1 GVSCFR 6 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 GVS(1)CFR 99.375 0.0351 5882900.0 23048.0 20632.0 28581.0 22087.0 26445.0 25375.0 19587.0 25940.0 28182.0 23778.0 True False 22719.331293514442 20584.2278716263 26231.180505850498 23711.351660072083 24889.557092870396 24289.770402014095 20601.119020072954 27145.26709862574 25007.84639038363 27887.995617806588 0.8146634704362928 0.7381035250336598 0.9405903839536532 0.8502350611720657 0.8924828242937016 0.8709758397446459 0.7387092031425544 0.9733674470779602 0.8967244090649537 1.0 14.767356627427134 -14.522878743834676 0.07090633463178928 1.5113611123866704 0.6789294153076465 0.35039671670698336 0.06831839963715221 360.9018648974517 1.8328924005704805 29.724581547434163 3.5879392603278735 3.000000009986276e-15 14.522878743834676 -0.8324316970790239 GVS(ph)GDRDENSFSLNSSISSSAR ddPTM_PC-9_Lapatinib_30min_R1 1 GVSGDRDENSFSLNSSISSSAR 22 1 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 GVS(0.995)GDRDENS(0.004)FS(0.001)LNSSISSSAR 59.661 0.00392 7007400.0 7058.1 7082.6 8423.1 7621.5 15370.0 10496.0 11317.0 10353.0 8434.3 8473.7 True False 6957.450199702985 7066.200674853644 7730.585232106271 8182.010534578686 14465.966818582645 10047.11054737103 11902.93888549372 10834.038175484671 7484.340316883564 9938.367754504485 0.7000596447590276 0.7110021332880287 0.77785260347228 0.8232750826583426 1.4555676722695297 1.010941715536463 1.1976754311691484 1.0901224872237427 0.7530754045090903 1.0 13.278793212320236 -6.021069069943185 24.387373930446348 1.095442326466217 0.7399059917749253 0.4925195095080718 0.16658270708694303 458.0958778727301 530244.5947919814 0.04880628181342554 0.06374997982805855 9.526446439220223e-07 6.021069069943185 -0.35553633469129164 GVS(ph)MPNMLEPK ddPTM_PC-9_AZD4547_30min_R2 9 GVSMPNMLEPK 11 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;O14639-4 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 GVS(1)MPNMLEPK;GVS(1)MPNMLEPK;GVS(1)MPNMLEPK;GVS(1)MPNMLEPK;GVS(1)MPNMLEPK;GVS(1)MPNMLEPK;GVS(1)MPNMLEPK;GVS(1)MPNMLEPK;GVS(1)MPNMLEPK 136.99 8.6926e-05 102408700.0 392492.0 497509.0 656414.0 867038.0 756281.0 751237.0 679020.0 770471.0 679531.0 705662.0 True False 517296.2916592436 658319.0549312473 647709.5214667113 667155.7847035661 651284.4375103045 704262.0316322172 739451.4645639602 651412.4106122465 715449.6213699685 680956.9881667963 0.7596607431136825 0.9667557075866237 0.9511753792415135 0.979732635536373 0.9564252204293061 1.0342239581506616 1.0859003981362125 0.9566131516851207 1.05065317458013 1.0 19.3772041494463 -3.990299212511851 0.9805164638674783 1.0101672849434997 2.6296096927868643e-31 0.7483345190954545 0.041929821432018455 4.01151856704762 0.9973446627905068 0.013711576136143162 6.21053081137568 0.00010225882248254755 3.990299212511851 -1.0101672849434997 GVS(ph)MPNMLEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 GVSMPNMLEPK 11 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;O14639-4 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 GVS(1)MPNMLEPK;GVS(1)MPNMLEPK;GVS(1)MPNMLEPK;GVS(1)MPNMLEPK;GVS(1)MPNMLEPK;GVS(1)MPNMLEPK 97.431 0.0032239000000000005 124462000.0 292456.0 348608.0 402031.0 508116.0 509305.0 433363.0 480397.0 426404.0 416156.0 353434.0 True False 341963.0245307032 383215.4983699897 411616.9437510576 479647.9078542974 409510.34132653364 410636.68138803897 434890.31838691 415211.3468123835 422241.4942101985 417508.7864179956 0.8190558753614863 0.9178621165263989 0.9858880989847258 1.1488330867702752 0.9808424508617307 0.9835402145930493 1.0416315357529091 0.994497266451988 1.0113355884861899 1.0 18.671447033672088 -5.025318533144242 2.189633513180903 1.0218114165152727 0.8131187445034506 0.6519911134659728 0.04682745653832661 0.25130180168448624 1.9710462718326671 0.013049208600674263 0.08431205901551313 9.43368709014128e-06 5.025318533144242 -0.20869267201182218 GVS(ph)MPNMLEPK ddPTM_PC-9_Lapatinib_30min_R1 8 GVSMPNMLEPK 11 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;O14639-4 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 GVS(1)MPNMLEPK;GVS(1)MPNMLEPK;GVS(1)MPNMLEPK;GVS(1)MPNMLEPK;GVS(1)MPNMLEPK;GVS(1)MPNMLEPK;GVS(1)MPNMLEPK;GVS(1)MPNMLEPK 146.67 0.00023624 79449600.0 570401.0 500463.0 548338.0 491351.0 481637.0 481494.0 421453.0 426435.0 481044.0 324620.0 True False 562266.9771412675 499304.20867185615 503255.7662858917 527486.5916388851 453308.0585947749 460901.62403733464 443273.774154633 446248.7268775047 426863.75910211133 380730.1344710392 1.476812382929561 1.311438637147952 1.3218175309004143 1.3854605766148231 1.1906282627840075 1.2105730077753902 1.1642728904831443 1.1720866999337802 1.1211714557219568 1.0 18.53840923695948 -1.5228787452803465 0.11883470527652523 0.8992381606459375 2.623630143637091 0.8825727837264898 0.04522782887366122 30.7988949136482 0.25302086093442633 0.3272641076515949 8.777580364176782 0.02999999999999938 1.5228787452803465 1.7243919829911536 GVS(ph)QEKEAQISSAIVSSVQSK ddPTM_PC-9_AZD4547_30min_R2 2 GVSQEKEAQISSAIVSSVQSK 21 1 Q12872;Q12872-2 Q12872 SFSWAP Splicing factor, suppressor of white-apricot homolog 1 GVS(0.852)QEKEAQIS(0.102)S(0.04)AIVS(0.005)S(0.001)VQSK;GVS(0.999)QEKEAQIS(0.001)S(0.001)AIVSSVQSK 78.418 0.00052045 39039000.0 126610.0 94179.0 163335.0 254093.0 213488.0 175552.0 151548.0 171564.0 143081.0 184038.0 True False 166869.3463484016 124620.51997927664 161169.0711788069 195515.78454771644 183848.87627112117 164574.70568821725 165035.47841262267 145052.72594851616 150643.969554349 177594.88563680765 0.9396067108016813 0.7017123242734207 0.9075096425265727 1.1009088682179626 1.035214925316618 0.9266860647371487 0.9292805804674481 0.8167618421465008 0.8482449762794695 1.0 17.438230510107623 -5.50925599760744 24.58889181780865 0.9495251384322542 0.8166473593815607 0.22805838419281688 0.09484291157928376 746.7457789788737 1347864.443333322 0.026958139256858603 0.05251075099203364 3.0955940439821035e-06 5.50925599760744 -0.13287777905069342 GVS(ph)QEKEAQISSAIVSSVQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GVSQEKEAQISSAIVSSVQSK 21 1 Q12872;Q12872-2 Q12872 SFSWAP Splicing factor, suppressor of white-apricot homolog 1 GVS(0.8)QEKEAQIS(0.126)S(0.07)AIVS(0.003)S(0.001)VQSK;GVS(0.856)QEKEAQIS(0.106)S(0.033)AIVS(0.004)S(0.001)VQSK 52.09 0.015125999999999999 32838000.0 33361.0 17494.0 28616.0 48887.0 44997.0 36230.0 42122.0 40182.0 37264.0 29067.0 True False 39008.358390215246 19230.68870618174 29298.31396678433 46148.01988379246 36180.16086366721 34330.035020730116 38131.899223128814 39127.2650763482 37808.91550343815 34336.617005754626 1.1360571247795803 0.5600635817721584 0.8532673431944124 1.3439885436604984 1.053690317179576 0.9998083100317249 1.1105316291566556 1.1395200951156805 1.1011252359864567 1.0 15.067460285242328 -5.596072610301734 10.953636695721395 1.1059959812211715 0.8127996266895915 0.351683420838266 0.15856605337879806 0.42826035559777115 61.66623955951273 0.0409878865611109 0.07102539696019525 2.5347048142273305e-06 5.596072610301734 -0.29319635453158 GVS(ph)QEKEAQISSAIVSSVQSK ddPTM_PC-9_Lapatinib_30min_R1 2 GVSQEKEAQISSAIVSSVQSK 21 1 Q12872;Q12872-2 Q12872 SFSWAP Splicing factor, suppressor of white-apricot homolog 1 GVS(0.987)QEKEAQIS(0.003)S(0.001)AIVS(0.009)S(0.001)VQSK;GVS(0.968)QEKEAQIS(0.024)S(0.008)AIVSSVQSK 84.946 0.00021839 26372000.0 117397.0 83793.0 106456.0 89053.0 94838.0 88738.0 74862.0 77580.0 94359.0 66471.0 True False 115722.89725202687 83598.9824567265 97703.59861204374 95602.25469209929 89259.81529868202 84942.88259838142 78737.98805742073 81184.65001971407 83731.29577567981 77960.42378295996 1.4843800435743753 1.0723259110220356 1.2532461199037135 1.2262921371265731 1.1449375332691791 1.0895641464810462 1.0099738333468467 1.0413572179357347 1.0740230967546538 1.0 16.250454312473536 -1.5228787452803665 0.2628759327706046 1.003109040125779 3.4903592784372592 0.6416545609419397 0.08393603342008552 34.50118091244798 0.47784977848355076 0.10101519848129206 38.58327472043846 0.029999999999998 1.5228787452803665 2.4872502383114803 GVS(ph)SESSGDREK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GVSSESSGDREK 12 1 E9PPJ0;Q13435;E9PJ04;H0YCG1 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 GVS(0.827)S(0.172)ESSGDREK 92.792 0.027358999999999998 6940300.0 29536.0 42881.0 36112.0 45505.0 60060.0 49492.0 52206.0 41012.0 46484.0 34650.0 True False 34535.861437408894 47137.942289343744 36973.04703552264 42955.50237920054 48291.67414431748 46896.55239431343 47260.66974129111 39935.47845580589 47163.74056091185 40931.7707107509 0.8437421796740865 1.1516223576656255 0.9032848174782607 1.0494415861642188 1.1798090653242488 1.1457249852617752 1.1546206997802297 0.9756596834770374 1.1522526326603335 1.0 15.320933458750735 -4.750463405394416 24.982821966920696 1.0795558833180148 0.8437416714313068 0.3850868922135625 0.08924354856046797 526.1640114032416 1197543.4651885226 0.02253033580689899 0.3317558267033223 1.77638294390535e-05 4.750463405394416 -0.23581421188670793 GVS(ph)WTTIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GVSWTTIR 8 0 Q8TE73 Q8TE73 DNAH5 Dynein heavy chain 5, axonemal 1 GVS(0.489)WT(0.489)T(0.021)IR 71.223 0.035996 12517000.0 26352.0 32599.0 32152.0 31694.0 35708.0 35368.0 36157.0 35455.0 25930.0 22608.0 True False 30812.873124275437 35835.21328071446 32918.62561713902 29918.287933334374 28711.27373202277 33513.239818194386 32731.947205988996 34524.34381767771 26309.17719525953 26706.651435170483 1.153752772004108 1.3418085516150633 1.2326002642842702 1.1202560532891976 1.0750607878235294 1.2548649125685665 1.2256103048128186 1.2927245447256621 0.9851170319545373 1.0 14.704911477172738 -8.27375195783916 24.81738649312038 0.992558447630004 1.2113411809950037 0.5771428072967277 0.07516042080095132 593.1800956167202 1195607.1334605783 0.07501669878774513 0.019951208639364823 5.324122534136795e-09 8.27375195783916 0.21878273336499965 GVSMS(ph)LPSSPLLPR ddPTM_PC-9_AZD4547_30min_R2 3 GVSMSLPSSPLLPR 14 0 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 GVS(0.004)MS(0.991)LPS(0.003)S(0.003)PLLPR;GVS(0.006)MS(0.994)LPSSPLLPR;GVS(0.064)MS(0.379)LPS(0.278)S(0.278)PLLPR 122.66 5.451e-05 12048100.0 40124.0 43653.7 75390.0 90311.0 73628.0 77901.0 67273.0 88048.0 62180.0 74945.0 True False 52882.59736895394 57763.90483036927 74390.27934104901 69491.19424104095 63406.02311179136 73029.83815517786 73260.16667493044 74442.20474175805 65466.707857014095 72321.19836148259 0.7312184887290056 0.7987133252638916 1.028609605847853 0.9608689542684782 0.8767280485988276 1.0097985073498545 1.0129833068964733 1.0293275889826112 0.9052215579973145 1.0 16.14213096294199 -5.1326932456173955 4.293190860673681 0.9768274043357978 0.7456084198107009 0.7512747613901875 0.04952528894956826 0.10685469467357664 3.152316336591309 0.01318047055648054 0.03965803815751354 7.367272849218596e-06 5.1326932456173955 -0.23121898452509693 GVSMS(ph)LPSSPLLPR ddPTM_PC-9_Lapatinib_30min_R1 1 GVSMSLPSSPLLPR 14 0 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 GVS(0.009)MS(0.976)LPS(0.007)S(0.007)PLLPR 63.16 0.045545999999999996 2688700.0 14731.0 10867.0 14357.0 11953.0 11570.0 11417.0 9137.5 9839.4 10031.0 8268.7 True False 14520.933238665459 10841.838129166486 13176.622879622666 12832.063494039103 10889.475347495207 10928.721524326897 9610.595039869126 10296.574444495694 8901.203148887167 9697.93377764981 1.497322375218822 1.1179534092254741 1.358704150980074 1.3231749966794282 1.1228655090006352 1.1269123686442983 0.9909940880415199 1.061728681652326 0.9178453217943376 1.0 13.243461686985482 -6.6647826374695205 1.0263442944371877 0.9848278532225019 1.3253542718460776 0.6986713800612085 0.09601106655219971 0.2958023619827911 0.6705470195493577 0.04952057241672227 0.04966441492154762 2.163801226018357e-07 6.6647826374695205 0.3405264186235757 GVSMSLPS(ph)SPLLPR ddPTM_PC-9_AZD4547_30min_R2 2 GVSMSLPSSPLLPR 14 0 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 GVS(0.002)MS(0.009)LPS(0.495)S(0.495)PLLPR;GVSMS(0.002)LPS(0.528)S(0.47)PLLPR 160.69 0.00048969 18640100.0 45197.0 50819.0 96460.0 126074.0 99696.0 100050.0 77973.0 106825.0 88039.0 89786.0 True False 59568.70584399885 67245.2479302907 95180.8773741557 97009.58712388307 85854.93127822514 93793.857683798 84912.44594628396 90317.65084429288 92692.56180481928 86642.61946873146 0.687521986399507 0.7761220556652134 1.0985457036938457 1.1196520571367647 0.990908767586481 1.0825371884981776 0.9800309185819122 1.0424159772418666 1.069826401523689 1.0 16.40278924019446 -5.163880938874168 4.301360356362128 1.0486747614432514 0.7092019387188728 0.8842418292673939 0.046080673252480844 0.06657441205051673 2.101857303937422 0.012075736539902437 0.035603572061898 6.856761776970803e-06 5.163880938874168 -0.3394728227243786 GVSMSLPS(ph)SPLLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GVSMSLPSSPLLPR 14 0 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 GVS(0.001)MS(0.019)LPS(0.49)S(0.49)PLLPR 88.09200000000001 0.024913 0.0 11306.0 12457.0 16427.0 15774.0 15857.0 16476.0 15734.0 15909.0 17224.0 15114.0 True False 13219.882496321268 13693.648634555042 16818.68197974442 14890.233919998002 12749.934680426943 15611.96955565965 14243.561615704592 15491.405606978833 17475.868415393365 17854.048557641836 0.7404417241076078 0.7669772259409436 0.9420094229857876 0.833997615270556 0.7141200853836456 0.874421815604252 0.7977776900135126 0.8676690643561764 0.9788182416426439 1.0 14.123963634294196 -8.18146125199953 2.3410476569502676 1.0013162037845333 0.8128450516854292 0.5672945299750816 0.0619818965486437 0.23521846584851408 2.3025758823850757 0.05754518634213345 0.017297302642169596 6.584741767628709e-09 8.18146125199953 -0.18847115209910414 GVSMSLPS(ph)SPLLPR ddPTM_PC-9_Lapatinib_30min_R1 2 GVSMSLPSSPLLPR 14 0 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 GVSMS(0.314)LPS(0.343)S(0.343)PLLPR;GVS(0.019)MS(0.09)LPS(0.446)S(0.446)PLLPR 99.73200000000001 0.0018780000000000001 6512800.0 51540.0 46091.0 39466.0 44952.0 40984.0 37010.0 34597.5 41382.7 40412.5 29190.5 True False 50805.030148721584 45984.27912132262 36221.25782316559 48257.92003547612 38573.401697644214 35427.16857452382 36388.78926313238 43305.49131697378 35860.81868750899 34236.039031103646 1.4839634369666688 1.343154185551244 1.0579862287882766 1.4095649321942152 1.1266899673352997 1.0347916866883469 1.0628796523474269 1.2649095088842048 1.04745816696053 1.0 15.063228177061246 -1.5228787452912727 0.4130850685181722 1.0883933007117301 7.990693785953566 0.5328007869405738 0.11464470912336973 64.35525743810481 0.8350663703331414 0.08027949313866299 365.1803893923868 0.02999999999924463 1.5228787452912727 6.9023004852418355 GVSMSLPSS(ph)PLLPR ddPTM_PC-9_AZD4547_30min_R2 1 GVSMSLPSSPLLPR 14 0 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 GVS(0.001)MS(0.243)LPS(0.16)S(0.596)PLLPR 118.76 9.7674e-05 8041800.0 28249.0 38943.0 53047.0 65194.0 62524.0 57499.0 55843.0 65603.0 51229.0 50988.0 True False 37231.594384298165 51530.563178128534 52343.56211970593 50164.530537259336 53843.621842799526 53903.57844038686 60812.91881777453 55465.56375696833 53936.86035392365 49202.92563953937 0.7566947269976754 1.047306893001474 1.0638302791824792 1.0195436528462694 1.09431748504668 1.0955360426183693 1.2359614398397765 1.1272818239165097 1.0962124640527493 1.0 15.586456481296208 -4.252315371571739 1.306249843085738 1.1047386957055758 3.07522602708508e-20 0.7214906473611287 0.06160033661137975 2.548815196751722 1.4708604576075668 0.018780803734889637 5.274071360330862 5.593512699356183e-05 4.252315371571739 -1.1047386957055758 GVSMSLPSS(ph)PLLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GVSMSLPSSPLLPR 14 0 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 GVSMS(0.003)LPS(0.218)S(0.779)PLLPR 104.7 0.00091751 10856000.0 27694.0 36894.0 46329.0 54372.0 65777.0 56372.0 60168.0 53655.0 52345.0 40855.0 True False 32382.04721856723 40556.592496048295 47433.659063710904 51325.713116402396 52888.469034145404 53415.7530827656 54468.45146140293 52246.61310217173 53110.446597989176 48261.68809199792 0.6709679768523548 0.8403475738092308 0.9828429327480505 1.0634877300305727 1.0958686097620076 1.1067941299720565 1.1286064291322235 1.0825691178182084 1.1004680668597502 1.0 15.558590758413533 -4.958194079913516 1.1098052612244453 1.0947807647491783 0.539631859051742 0.9432664327986617 0.03297035923337295 0.24821955429282117 0.31232370878128435 0.010034893378223456 0.15068929800789369 1.1010471575549827e-05 4.958194079913516 -0.5551489056974362 GVSMSLPSS(ph)PLLPR ddPTM_PC-9_Lapatinib_30min_R1 2 GVSMSLPSSPLLPR 14 0 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 GVSMSLPS(0.028)S(0.972)PLLPR;GVSMS(0.001)LPS(0.297)S(0.702)PLLPR 212.83 1.0917e-12 16518200.0 114020.0 86277.0 103393.0 84825.0 75950.0 81725.0 61152.0 71195.0 89182.0 59960.0 True False 112394.05389129293 86077.23090734308 94892.42664852164 91063.31346790484 71482.77032344513 78229.81226027984 64318.15134096597 74502.97961012584 79137.3840319066 70324.00610832205 1.5982316723846648 1.2240092063975407 1.3493603663926108 1.2949107780867524 1.0164775057515667 1.1124197353003504 0.9145973743574123 1.0594245654231758 1.1253253108193104 1.0 16.101729637573214 -3.56130682349347 0.3875290574067956 1.0031179318383088 2.7474222153305097 0.7488516872568689 0.0963072782375097 7.595109327639959 0.43052780013128517 0.07770849061343645 7.460195412848315 0.0002745953486658831 3.56130682349347 1.744304283492201 GVSS(ph)ESSGDREK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GVSSESSGDREK 12 1 E9PPJ0;Q13435;E9PJ04;H0YCG1 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 GVS(0.224)S(0.757)ES(0.017)S(0.002)GDREK 131.79 0.0013619 0.0 3859.4 5006.6 7440.2 6185.6 8286.4 6915.6 8604.9 6906.4 6842.8 6210.3 True False 4512.720193375405 5503.622160533295 7617.602585115628 5839.040885985776 6662.7394044201155 6552.933761781983 7789.78157791893 6725.114317935679 6942.863004694252 7336.178229292248 0.615132300815266 0.7502028970013522 1.0383611666766348 0.7959240770175635 0.9082030447156814 0.8932353545633762 1.0618310153392283 0.9167054163274436 0.9463869044201314 1.0 12.840812973675835 -5.039621874115208 4.018758381106338 0.9373326855153131 0.6337767873596128 0.6848144415939321 0.07357514187092686 0.11422925168336613 3.9325182189077954 0.018918620270135342 0.0673176833339307 9.12805242901026e-06 5.039621874115208 -0.3035558981557003 GVSS(ph)PVETR ddPTM_PC-9_AZD4547_30min_R2 3 GVSSPVETR 9 0 A8MVZ6;Q96G01-4;Q96G01-3;Q96G01 A8MVZ6 BICD1 Protein bicaudal D homolog 1 1 GVS(0.386)S(0.614)PVETR;GVS(0.125)S(0.875)PVETR;GVS(0.111)S(0.889)PVETR 128.91 0.0013151 10397700.0 60918.0 58990.0 84211.0 114504.0 100085.0 77151.0 72478.0 102770.0 70191.0 77701.0 True False 80288.65682688507 78057.36388767697 83094.30711751 88106.87186916503 86189.92534285391 72326.73577374029 78928.40159150958 86889.25791966275 73901.15296223339 74980.7116403439 1.0707908083348356 1.041032582647264 1.1082091020432583 1.1750604914472231 1.149494629449193 0.9646045521769145 1.052649406291332 1.1588214624641062 0.9856021814878368 1.0 16.194231897828466 -6.738126961496935 24.999673838848484 1.0435314125160369 1.1087813779120785 0.275337566388682 0.06077761700432421 398.01237158866223 426818.31515472097 0.021294451015019308 0.021281758391701957 1.8275658680743461e-07 6.738126961496935 0.06524996539604166 GVSS(ph)PVETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GVSSPVETR 9 0 A8MVZ6;Q96G01-4;Q96G01-3;Q96G01 A8MVZ6 BICD1 Protein bicaudal D homolog 1 1 GVS(0.102)S(0.898)PVETR 125.97 0.0014095000000000002 3668100.0 23120.0 25224.0 27770.0 28282.0 37094.0 29432.0 26491.0 32275.0 22987.0 21109.0 True False 27033.7593591852 27728.07202039148 28432.142118311465 26697.45123148112 29825.69698150705 27888.534107925178 23981.580701768813 31427.81544818922 23323.141387868516 24935.894601247935 1.0841303186223876 1.111974222853982 1.1402094279340016 1.0706434101684497 1.196094924944638 1.1184092070444296 0.9617293097063635 1.2603444131744281 0.93532402830662 1.0 14.605936341671475 -8.297332622633947 24.999951137636103 0.9676619238946711 1.1143222427770385 0.38772078802755716 0.07543017869923832 682.5863475239424 475421.4498361257 0.06818518282021115 0.017608503748529774 5.042749295310987e-09 8.297332622633947 0.1466603188823674 GVSS(ph)PVETR ddPTM_PC-9_Lapatinib_30min_R1 2 GVSSPVETR 9 0 A8MVZ6;Q96G01-4;Q96G01-3;Q96G01 A8MVZ6 BICD1 Protein bicaudal D homolog 1 1 GVS(0.115)S(0.885)PVETR;GVS(0.362)S(0.638)PVETR 145.9 4.3066e-11 5021900.0 65243.0 58900.0 77944.0 57024.0 64568.0 57656.0 51489.0 47989.0 58323.0 51142.0 True False 64312.62285589912 58763.62066880521 71535.745192541 61217.735186487575 60770.237185572216 55190.187282700485 54154.84848238813 50218.74413245762 51754.04957158269 59981.82655756854 1.0722018075620627 0.9796904169366344 1.1926236544978068 1.0206047181262954 1.0131441583768208 0.9201151490398647 0.9028542742094079 0.8372326588664212 0.8628288356959403 1.0 15.872237835157616 -6.663280055065088 1.7192071200407206 0.886786158007204 1.070517502914791 0.5902924024815139 0.06417028665503234 0.23751400134314135 1.4474123367965663 0.025673109490803876 0.02523477429182482 2.1713005628082314e-07 6.663280055065088 0.18373134490758714 GVSSES(ph)SGDREK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GVSSESSGDREK 12 1 E9PPJ0;Q13435;E9PJ04;H0YCG1 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 GVS(0.057)S(0.03)ES(0.863)S(0.05)GDREK;GVS(0.002)S(0.025)ES(0.595)S(0.378)GDREK 77.77600000000001 0.0081137 5069900.0 23444.0 34687.0 34383.0 33134.0 54999.0 39732.0 30293.0 32971.0 39367.0 31743.0 True False 27412.606159893505 38130.49612160317 35202.82111825362 31277.609401877366 44222.340763625 37648.38397581147 27423.427737672515 32105.546185662173 39942.66789995303 37497.75462255027 0.7310466036120522 1.0168741170083926 0.9387981086495102 0.8341195284015153 1.1793330349713986 1.0040170232798584 0.7313351962994795 0.8561991646922414 1.065201591455624 1.0 15.194516588707362 -4.7505935038905 24.914543719761433 0.9506698525442215 0.7310461159528088 0.23976785599062378 0.12075764793546245 737.8012490165983 1694720.5432979283 0.031268191925901696 0.4503615011951907 1.7758508852507794e-05 4.7505935038905 -0.21962373659141277 GVSSES(ph)SGDREK ddPTM_PC-9_Lapatinib_30min_R1 1 GVSSESSGDREK 12 1 E9PPJ0;Q13435;E9PJ04;H0YCG1 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 GVS(0.003)S(0.008)ES(0.608)S(0.381)GDREK 55.98 0.037021 9759800.0 9856.2 13043.0 13272.0 10644.0 15477.0 12046.0 14308.0 14597.0 16017.0 12480.0 True False 9715.648780594289 13012.79973485953 12180.827391401554 11426.795267343108 14566.673288952743 11530.820660597507 15048.79823041832 15275.229908968397 14212.996793512682 14637.151371445287 0.6637663664220859 0.8890254260979631 0.832185654318256 0.7806707041122043 0.9951849864291193 0.7877776466186085 1.0281234270608208 1.0435930818320223 0.9710220542803116 1.0 13.837347188487604 -6.018969798590154 0.40435824272878085 1.0313466247004193 0.6898110064460086 0.5583824979383215 0.08097896006431526 1.6943628120659604 0.4388307789115157 0.0761037357050369 0.2557484859434797 9.5726063814487e-07 6.018969798590154 -0.3415356182544107 GVT(ph)LGFR ddPTM_PC-9_AZD4547_30min_R2 1 GVTLGFR 7 0 D6RAN4;P32969;H0Y9V9;E7ESE0;A0A2R8Y5Y7 D6RAN4 RPL9 60S ribosomal protein L9 1 GVT(1)LGFR 85.161 0.016337 0.0 10564.0 10487.0 13154.0 13992.0 11725.0 10309.0 9527.9 11947.0 8908.7 9674.8 True False 13923.132255149776 13876.717665537682 12979.569365329085 10766.360574245064 10097.186138232102 9664.376600322583 10375.864642011964 10100.865664748579 9379.595694528482 9336.08819677993 1.491323985130297 1.4863524608008567 1.3902577923166806 1.1531982504148195 1.0815221456149782 1.0351633785610423 1.1113717462085093 1.0819162642692712 1.0046601421100068 1.0 13.188602474719346 -5.754624155862634 1.8892891810871812 1.056793594135149 1.495395240557817 0.9690768230956557 0.03260216090391738 0.052735722803314566 0.38365088244602347 0.010176872716787634 0.02074408155643767 1.759445602576516e-06 5.754624155862634 0.4386016464226681 GVT(ph)PAGFPK ddPTM_PC-9_AZD4547_30min_R2 1 GVTPAGFPK 9 0 Q8WX93-3;Q8WX93;A0A3B3ISX8;Q8WX93-4 Q8WX93-3 PALLD Palladin 1 GVT(1)PAGFPK 99.973 0.0097045 11418000.0 114260.0 105100.0 109220.0 167590.0 155670.0 159290.0 134120.0 193710.0 148620.0 158850.0 True False 150592.3032443593 139071.51965748184 107771.67143691967 128954.7147396892 134057.90755979472 149329.57111896275 146056.42017513263 163776.57051296925 156475.74978625673 153288.7098501767 0.9824096203272057 0.907252202679567 0.7030633341637159 0.841253833147455 0.8745452140005743 0.9741720134830308 0.9528191627282083 1.0684190027631084 1.0207910937419657 1.0 17.22589191674998 -6.941784427983262 1.626551938326382 1.022427030510796 0.8506546196551658 0.5095641974976555 0.07018124256136422 0.3218473085076681 1.7378764115587266 0.035469364203524666 0.02793996622172703 1.1434457694550573e-07 6.941784427983262 -0.17177241085563033 GVT(ph)PAGFPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GVTPAGFPK 9 0 Q8WX93-3;Q8WX93;A0A3B3ISX8;Q8WX93-4 Q8WX93-3 PALLD Palladin 1 GVT(1)PAGFPK;GVT(1)PAGFPK 104.22 0.0066446 18173000.0 253110.0 239660.0 231090.0 239870.0 233470.0 155839.0 185738.0 168209.0 148931.0 116299.0 True False 295956.5238496268 263451.8609422389 236600.06201370488 226430.8615690325 187723.22947841816 147666.5285011196 168143.55201333057 163793.69198216722 151108.83412522965 137383.08807762244 2.1542427673660187 1.9176440465029194 1.7221920494320533 1.6481712904946308 1.366421676097084 1.0748523021821066 1.2239028425269365 1.1922405754165506 1.0999085567202571 1.0 17.067844893088946 -5.614244518509128 0.5821892072809987 1.0703255209228686 2.353146360154322 0.960014359755528 0.07528178745833088 0.3245435164570919 0.15955946819101893 0.05022250679685187 0.2505474715792525 2.4308350036323958e-06 5.614244518509128 1.2828208392314535 up GVT(ph)PAGFPK ddPTM_PC-9_Lapatinib_30min_R1 1 GVTPAGFPK 9 0 Q8WX93-3;Q8WX93;A0A3B3ISX8;Q8WX93-4 Q8WX93-3 PALLD Palladin 1 GVT(1)PAGFPK 99.973 0.0097045 13164000.0 149880.0 124700.0 169180.0 130430.0 113690.0 101860.0 103680.0 85818.0 116390.0 58181.0 True False 147742.68371537398 124411.26481154512 155270.67345368577 140022.257301725 107002.97772313988 97503.68524725745 109048.04308986376 89805.41757401195 103280.93255896501 68237.50832869053 2.165124245213031 1.8232093735350574 2.2754446528992336 2.0519837363823044 1.5680962031573824 1.4288869514050226 1.598066016194416 1.316071172198021 1.5135507595247355 1.0 16.05827734760848 -6.34957421939939 2.966987304794388 1.4092543566209659 2.081643618097057 0.7690142833425084 0.1832169037677206 0.12915453762162024 2.2089748028535836 0.05769496349931467 0.06793040491630879 4.4712173372753903e-07 6.34957421939939 0.6723892614760909 GVTDHTQR ddPTM_PC-9_AZD4547_30min_R2 3 GVTDHTQR 8 0 Q14204;A0A2R8Y706;A0A2R8Y6H2;A0A2R8Y5T0;A0A2R8Y542 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ;; 134.48 0.0029289000000000003 2075870.0 8190.7 11010.9 6817.5 10485.0 7826.9 8236.3 5902.23 5926.6 11957.3 14384.000000000002 False True 10795.17222285642 14569.958095114793 6727.0954955246325 8067.845241635185 6740.2700371282635 7721.282858981173 6427.51703586543 5010.7801497195105 12589.338466688232 13880.42053814886 0.7777265964807794 1.0496769932201127 0.48464637487285966 0.5812392513225064 0.48559552058263283 0.5562715364249987 0.4630635662802927 0.36099627788278565 0.9069853778628518 1.0 13.760763657776213 -5.266589409699171 24.967928747898004 0.5701271335008403 0.9137018017642756 0.26081977683384094 0.20129804866358247 416.7087368531663 2020260.1397297983 0.049024391268993495 0.10721410003491007 5.412658041581123e-06 5.266589409699171 0.3435746682634353 GVTDHTQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GVTDHTQR 8 0 Q14204;A0A2R8Y706;A0A2R8Y6H2;A0A2R8Y5T0;A0A2R8Y542 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ;;;; 153.08 8.882e-05 2905630.0 3571.53 8811.4 10904.8 5884.450000000001 16130.099999999999 15071.9 6685.17 9361.3 16637.4 14225.600000000002 False True 4176.11948806707 9686.137559486091 11164.81178868429 5554.763344144305 12969.5226958917 14281.503031436447 6051.902301160538 9115.575794117229 16880.69050013154 16804.58867021237 0.24851066396344548 0.5763983724668984 0.6643906618479102 0.33055039032229433 0.771784597077424 0.8498573402603826 0.36013391460679267 0.5424456363085756 1.0045286338995054 1.0 14.036567609448717 -9.217348450267366 0.08957468370705438 1.6192438404308362 1.6646525695360767e-15 0.4156477747220515 0.197147073317398 37.6523101602669 1.2969790375048544 14.183013991539012 8.536922263995164 6.062497181904819e-10 9.217348450267366 -1.6192438404308347 GVTDHTQR ddPTM_PC-9_Lapatinib_30min_R1 4 GVTDHTQR 8 0 Q14204;A0A2R8Y706;A0A2R8Y6H2;A0A2R8Y5T0;A0A2R8Y542 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ;;; 140.09 0.0021593000000000003 4019320.0 8461.66 13642.8 10883.880000000001 10417.140000000001 14693.400000000001 10171.0 18242.2 17327.03 15778.2 11991.460000000001 False True 8340.995176721599 13611.210934811132 9989.049399391764 11183.25122616034 13829.16310033587 9736.010039759027 19186.69185622987 18132.107069232898 14001.092964188167 14064.167883383918 0.5930670940423038 0.9677935479490449 0.7102481627223255 0.7951591106483284 0.9832905305883263 0.6922563866193332 1.364225172460999 1.2892413699537133 0.995515204332119 1.0 13.779736576636566 -7.255344812635213 24.988336431131536 1.1863488870006074 0.8037243518797107 0.579812480215355 0.15431972142307854 336.0767872980387 1377952.1720014836 0.05801960762405255 0.04375652934134713 5.554630664523982e-08 7.255344812635213 -0.38262453512089667 GVTECYECHPKPTQR ddPTM_PC-9_Lapatinib_30min_R1 1 GVTECYECHPKPTQR 15 1 K7EPL2;Q9UBT2-2;Q9UBT2 K7EPL2 UBA2 SUMO-activating enzyme subunit 2 0 74.475 0.0071905 2437200.0 13040.0 12463.0 15094.0 14635.0 15445.0 12242.0 11569.0 13183.0 13918.0 11211.0 False True 12854.04720875688 12434.14268922444 13853.029584524946 15711.306720928827 14536.555466038326 11718.438197495829 12167.986212448257 13795.530306907605 12350.408276962577 13148.806412281503 0.9775828166996735 0.9456480154434749 1.053557954247898 1.194884632741558 1.1055418271623962 0.8912168777958694 0.9254061418900258 1.0491849886862763 0.9392798015055427 1.0 13.682644223839894 -6.753219910479868 24.999959557804893 0.9618659064566775 1.0569853492735528 0.2845872226818482 0.07483050399572339 281.0711661362117 854891.926067254 0.02799313590614022 0.027533965261770283 1.7651437915669637e-07 6.753219910479868 0.09511944281687534 GVTIPYRPKPSS(ph)SPVIFAGGQDR ddPTM_PC-9_AZD4547_30min_R2 2 GVTIPYRPKPSSSPVIFAGGQDR 23 2 Q15366-2;Q15366;Q15366-6;Q15366-3;H3BSS4 Q15366-2 PCBP2 Poly(rC)-binding protein 2 1 GVTIPY(0.001)RPKPS(0.016)S(0.568)S(0.415)PVIFAGGQDR;GVTIPY(0.001)RPKPS(0.067)S(0.737)S(0.194)PVIFAGGQDR 83.465 0.00015979 411200000.0 210552.0 160223.0 170757.0 180270.0 151323.0 139304.0 195286.0 176507.0 119842.0 136705.0 True False 277503.15624633664 212011.9514184651 168492.6506093584 138711.5366437361 130314.4134751125 130593.29885840877 212666.07568088983 149231.89887735632 126176.60345770798 131918.99955976385 2.1035874830192154 1.6071373503891406 1.2772432414712591 1.051490210709906 0.9878365808563881 0.9899506461860751 1.6120958799762939 1.1312388615390396 0.9564702876672866 1.0 17.009292837333014 -4.912655256224604 1.5603592905924057 1.1217537220122014 2.323239938778672 0.7504305431438237 0.1816282018964994 0.43203476046069433 1.221834388786917 0.055256098897268145 0.7430273867880325 1.2227699120727532e-05 4.912655256224604 1.2014862167664708 up GVTIPYRPKPSS(ph)SPVIFAGGQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GVTIPYRPKPSSSPVIFAGGQDR 23 2 Q15366-2;Q15366;Q15366-6;Q15366-3;H3BSS4 Q15366-2 PCBP2 Poly(rC)-binding protein 2 1 GVTIPYRPKPS(0.124)S(0.513)S(0.363)PVIFAGGQDR 83.395 0.00016783 98772000.0 77588.0 72257.0 72209.0 87165.0 75388.0 78772.0 80067.0 66414.0 65626.0 63449.0 True False 90722.11596714777 79430.19743012305 73930.73641415744 82281.42764274286 60616.26257728613 74641.05764981931 72482.47412511896 64670.7028714497 66585.65609780561 74951.80143799243 1.2104060773269354 1.0597503449711692 0.9863770449242675 1.0977911946628023 0.8087365668913764 0.9958540851292255 0.9670544634618776 0.8628305341660364 0.8883796629343442 1.0 16.193675532764956 -1.5228787574208174 0.48823282116086725 0.9188258506820862 9.391231994211946 0.5752292903352009 0.07287886544429936 71.64055297828857 0.7858344846348533 0.04050579202578368 618.7464237529886 0.02999999916136538 1.5228787574208174 8.47240614352986 GVTIPYRPKPSS(ph)SPVIFAGGQDR ddPTM_PC-9_Lapatinib_30min_R1 1 GVTIPYRPKPSSSPVIFAGGQDR 23 2 Q15366-2;Q15366;Q15366-6;Q15366-3;H3BSS4 Q15366-2 PCBP2 Poly(rC)-binding protein 2 1 GVTIPYRPKPS(0.133)S(0.433)S(0.433)PVIFAGGQDR 64.749 0.0053002 102550000.0 63068.0 71619.0 68642.0 54988.0 65726.0 76871.0 46136.0 50476.0 70875.0 51496.0 True False 62168.63875474526 71453.17060575823 62998.51972578251 59032.00095459069 61860.12590228775 73583.40652505329 48524.696334818254 52821.299231697536 62892.31115316293 60397.014985893125 1.0293329690095765 1.1830579809688855 1.0430733992482413 0.97739931300212 1.0242248878812366 1.2183285306772214 0.8034287182264244 0.8745680435371674 1.0413148922650006 1.0 15.882189628247703 -7.267567519121794 24.99964529913166 0.9193752581167334 1.0751821283141627 0.38635898562386495 0.09178249363336864 536.4474035534115 2188418.003212592 0.03830439425981418 0.026568984302261605 5.400481477496296e-08 7.267567519121794 0.15580687019742934 GVVCIDEFDK ddPTM_PC-9_Lapatinib_30min_R1 1 GVVCIDEFDK 10 0 P25205;J3KQ69;A0A499FHX9;P25205-2 P25205 MCM3 DNA replication licensing factor MCM3 0 90.62899999999999 0.031666 0.0 7924.6 5909.6 6854.2 5890.1 6351.6 5146.9 8014.5 5266.7 5776.4 6600.2 False True 7811.593750806339 5895.916684284743 6290.674133977136 6323.277602797598 5978.011375726058 4926.779085009903 8429.45159475033 5511.410109033626 5125.801003811366 7741.035775786313 1.0091147976916381 0.7616444174986198 0.812639847713163 0.8168516185620259 0.7722495475896218 0.6364495950814094 1.088930711458195 0.7119732124573204 0.6621595807430177 1.0 12.918310901240332 -4.7547895155462685 24.90000621138516 0.8008684380061266 1.0091151688929736 0.16867342524308437 0.1340003440714118 382.1381356969015 1430755.0135511754 0.03207041563010187 0.30235551726655974 1.7587758128400305e-05 4.7547895155462685 0.20824673088684698 GVVDSDDLPLNVSR ddPTM_PC-9_AZD4547_30min_R2 2 GVVDSDDLPLNVSR 14 0 P14625 P14625 HSP90B1 Endoplasmin 0 ; 215.72 1.0395e-14 27409000.0 67415.0 70644.0 144907.0 186497.0 144685.0 112177.0 95995.0 171780.0 96098.0 115634.0 False True 88851.56768089006 93478.29148128585 142985.43849944824 143502.99799992732 124597.98519489235 105162.55445672589 104538.36903304377 145235.34811170242 101177.54409204469 111585.68885625029 0.7962631103649201 0.8377265260396322 1.2813958489215274 1.2860340736417764 1.1166125913817235 0.9424376506937286 0.9368438740178842 1.3015589149501163 0.9067250928780496 1.0 16.767792484219946 -5.143637392390296 7.141710831740543 1.103153899062999 0.8080594745199541 0.3757267058969599 0.1441659344301462 0.2591501616211901 14.133896616151723 0.03806011727331392 0.10266499073840712 7.183938530221254e-06 5.143637392390296 -0.2950944245430449 GVVDSDDLPLNVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GVVDSDDLPLNVSR 14 0 P14625 P14625 HSP90B1 Endoplasmin 0 ; 207.34 3.3063999999999996e-10 16507300.0 51016.0 66186.0 63338.0 72145.0 67249.0 58369.0 65262.0 65544.0 49428.0 47248.0 False True 59652.00118807057 72756.50867196424 64848.21813070263 68102.94954724594 54072.04120098585 55308.02688724806 59079.91090403671 63823.53944960844 50150.79099141099 55813.688385037814 1.0687700976963512 1.3035603053151448 1.1618694267853966 1.2201836416441267 0.9687953397375032 0.99094018846593 1.058520098088957 1.1435105132152108 0.8985392731159316 1.0 15.768331367972753 -6.256551472029579 24.986196423864847 1.0186943503595478 1.1948985888144177 0.539992663801216 0.08041027452063843 322.5766418580846 1648957.3863709106 0.023389978962713814 0.02924080060730587 5.539218899302422e-07 6.256551472029579 0.17620423845486988 GVVDSDDLPLNVSR ddPTM_PC-9_Lapatinib_30min_R1 2 GVVDSDDLPLNVSR 14 0 P14625 P14625 HSP90B1 Endoplasmin 0 ; 236.08 3.1728e-26 32741000.0 106155.0 92952.0 117738.0 85018.0 95569.0 107868.0 76040.0 87635.0 113472.0 74178.0 False True 104641.21023355726 92736.77535495396 108058.03612182305 91270.50733173401 89947.81931588314 103254.7370925895 79976.97913342257 91706.84202729659 100691.5884468672 86999.56846402797 1.2027784974223596 1.0659452338927196 1.2420525530135498 1.0490914948557701 1.0338881089171632 1.1868419454894494 0.9192801820217184 1.0541068610612128 1.1573803206679183 1.0 16.408720624460805 -5.7929514610083235 24.992428922745194 1.0581617809702615 1.1598274644120647 0.28285396881061486 0.08196423806990472 263.42093334482496 208919.68741770895 0.02254304798143789 0.03343985015665366 1.6108256593032616e-06 5.7929514610083235 0.10166568344180327 GVVDSEDLPLNISR ddPTM_PC-9_AZD4547_30min_R2 4 GVVDSEDLPLNISR 14 0 P07900;P07900-2;P08238 P07900;P08238 HSP90AA1;HSP90AB1 Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta 0 ;;; 219.74 4.529600000000001e-15 74796000.0 118827.0 113495.0 142298.0 198838.0 153988.0 150446.0 138725.0 167679.0 119070.0 147584.0 False True 156611.51424485803 150180.03923430928 140411.03554413834 152998.9711164766 132609.42422636147 141038.58783704834 151071.25625406535 141768.06343009794 125363.79711377718 142417.1290810736 1.0996676822189275 1.0545082617752848 0.9859139588764407 1.0743017508054042 0.9311339519480911 0.9903203971817147 1.060766055521771 0.9954425029126507 0.8802578588872657 1.0 17.11976314991354 -1.5228787454969401 0.41108869954858823 0.976907689566857 3.119286291776918 0.350667713822002 0.05159003498965593 91.92344418937658 1.1969889889698113 0.03653682637533209 160.87683906296 0.029999999985037624 1.5228787454969401 2.142378602210061 GVVDSEDLPLNISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 GVVDSEDLPLNISR 14 0 P07900;P07900-2;P08238 P07900;P08238 HSP90AA1;HSP90AB1 Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta 0 ;;;;; 156.0 0.0002744 83313200.0 135731.4 142586.2 170311.4 183660.4 184494.4 159370.7 170641.1 163723.4 161791.7 126758.3 False True 158708.0452026521 156741.21561663272 174372.26968558168 173370.50322305103 148344.04672413183 151013.01993591714 154476.73967342108 159425.83422928132 164157.5975326757 149738.5763718493 1.0599008555319018 1.0467657661402736 1.1645113364278217 1.157821233671382 0.9906869045939477 1.0085111238195759 1.0316429033611578 1.0646944701369099 1.0962946323532508 1.0 17.192086417749167 -6.26500826898121 24.996272860993525 1.0340169308972744 1.1070196194329904 0.40136283888356383 0.04499695410803211 369.21337304403716 2585944.0673970557 0.015145600763091951 0.017871959834983908 5.43239988086736e-07 6.26500826898121 0.07300268853571601 GVVDSEDLPLNISR ddPTM_PC-9_Lapatinib_30min_R1 4 GVVDSEDLPLNISR 14 0 P07900;P07900-2;P08238 P07900;P08238 HSP90AA1;HSP90AB1 Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta 0 ;;; 164.48 0.00076916 213023000.0 238240.0 262193.0 245010.0 263143.0 265904.0 294117.0 284572.0 237030.0 255101.0 232030.0 False True 234842.65391213505 261585.90821758963 224866.22356595012 282495.41403931536 250264.04950737784 281538.30153021414 299305.74573850987 248043.27912055748 226368.83904737965 272136.07633945975 0.862960387579024 0.961232012073585 0.826300674980903 1.0380667563051562 0.919628345031333 1.0345497198211462 1.099838543145448 0.9114678305685235 0.8318222342744792 1.0 18.053968697860142 -5.763399628944609 24.999690094483626 0.9779835258255728 0.8912711303506184 0.2267268051048258 0.07826435591486398 86.61184554304423 1104616.2798804932 0.02269290165898286 0.03565535474282662 1.7242505415175911e-06 5.763399628944609 -0.08671239547495435 GVVIPT(ph)WNISPIKK ddPTM_PC-9_AZD4547_30min_R2 1 GVVIPTWNISPIKK 14 1 A0A087WUE6;Q3T8J9-2;Q3T8J9-3;Q3T8J9;A4PB68 A0A087WUE6 GON4L GON-4-like protein 1 GVVIPT(0.713)WNIS(0.287)PIKK 70.281 0.023569 7370100.0 67314.0 68836.0 77379.0 97106.0 82671.0 93093.0 82022.0 88428.0 73331.0 105570.0 True False 88718.45178182052 91085.8908386529 76352.90390145947 74719.71197274457 71193.55865533369 87271.87999358142 89321.79910233161 74763.48447328922 77207.12695179637 101874.026433007 0.8708642908127552 0.8941031784833943 0.749483519743569 0.7334520347233032 0.6988391560448532 0.8566646774383846 0.8767867750968907 0.7338817075464682 0.7578686114126278 1.0 16.636426746619946 -11.342718239132383 6.731759560574016 1.0125067144204627 0.7958542030289295 0.44516279742416565 0.06801989051175367 0.01419051557018621 0.0003797769943993013 0.0731998437820956 0.017356150320441684 4.5423621970966e-12 11.342718239132383 -0.2166525113915332 GVVIPTWNIS(ph)PIKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GVVIPTWNISPIKK 14 1 A0A087WUE6;Q3T8J9-2;Q3T8J9-3;Q3T8J9;A4PB68 A0A087WUE6 GON4L GON-4-like protein 1 GVVIPT(0.012)WNIS(0.988)PIKK 68.26100000000001 0.014863 6345000.0 27078.0 26665.0 25980.0 33027.0 35416.0 29005.0 32126.0 32802.0 26540.0 25628.0 True False 31661.770585121816 29312.124977154235 26599.46172969868 31176.604264978683 28476.48903588323 27483.9267396157 29082.79270790173 31940.982256591855 26928.097291252914 30274.153528863633 1.045835040604363 0.968222776210995 0.8786195030800292 1.0298092805552646 0.9406204870016764 0.90783468853761 0.9606475926791463 1.0550578144534761 0.8894748210079413 1.0 14.885799002003058 -11.177378877188607 5.90865503958783 1.000329060656216 0.963799357503691 0.03143935628896577 0.059911449655028495 0.00025439536702959013 1.4875350663973057e-05 0.05682346029126007 0.013657809158437515 6.6469302700660425e-12 11.177378877188607 -0.03652970315252513 GVVIPTWNIS(ph)PIKK ddPTM_PC-9_Lapatinib_30min_R1 1 GVVIPTWNISPIKK 14 1 A0A087WUE6;Q3T8J9-2;Q3T8J9-3;Q3T8J9;A4PB68 A0A087WUE6 GON4L GON-4-like protein 1 GVVIPT(0.02)WNIS(0.98)PIKK 59.728 0.026813999999999998 7013900.0 36280.0 34785.0 33678.0 31838.0 33786.0 29696.0 28012.0 29988.0 26578.0 27660.0 True False 35762.64054706282 34704.45746968403 30909.124840839457 34179.472728454544 31798.7739058317 28425.971304757073 29462.32429623136 31381.3519565763 23584.505761252418 32440.99414536672 1.1023904010713095 1.069771700403965 0.9527798285816081 1.0535889429065515 0.9802034352998783 0.8762361343607875 0.9081819183534244 0.9673363219375397 0.7269970104976206 1.0 14.98553041077585 -6.018476564796727 0.6428865446991291 0.8838072595065006 1.1004034028341734 0.4554594510893306 0.07634962759694079 0.9438269111139445 0.7496468145558458 0.04644177128528946 0.12261687314277303 9.583484288774985e-07 6.018476564796727 0.21659614332767274 GVVPLAGTDGETTTQGLDGLS(ph)ER ddPTM_PC-9_AZD4547_30min_R2 1 GVVPLAGTDGETTTQGLDGLSER 23 0 P09972;K7EKH5;C9J8F3;J3KSV6;J3QKP5;A8MVZ9 P09972 ALDOC Fructose-bisphosphate aldolase C;Fructose-bisphosphate aldolase 1 GVVPLAGTDGET(0.001)T(0.001)TQGLDGLS(0.998)ER 86.575 0.00055751 0.0 5300.4 6559.2 7349.0 8873.4 8435.0 8211.0 6747.6 7206.0 9771.3 6410.4 True False 6985.816944831111 8679.33312785303 7251.547458248701 6827.7747226633865 7263.94584869832 7697.564871980673 7348.123328166744 6092.47827740674 10287.79096949568 6185.973847173901 1.1292994631754907 1.403066573231349 1.1722564041491403 1.1037509842985669 1.1742606787800918 1.2443578104516804 1.1878684762826435 0.9848858769731341 1.6630834891414419 1.0 12.594785018730668 GVVPLAGTNGETTTQGLDGLSER ddPTM_PC-9_AZD4547_30min_R2 3 GVVPLAGTNGETTTQGLDGLSER 23 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8;H3BU78 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ;; 178.01 7.882999999999999e-42 8486700.0 29947.3 26531.7 40064.0 53021.0 39076.0 38773.0 40490.0 44124.0 33650.4 36024.0 False True 39469.91845746373 35107.55316932834 39532.72518264743 40797.82761628412 33650.9719008578 36348.518180648694 44093.531560476535 37305.649668650396 35429.091445346836 34762.81072485224 1.1354064195173474 1.0099169899466627 1.1372131412373148 1.1736055504602045 0.9680164290282898 1.045615053061944 1.26841100132774 1.073148255010929 1.019166480114862 1.0 15.08525711460361 -8.215648190488302 4.220860773379368 1.007196750901529 1.1021421806568028 0.1768570971213631 0.0807894389382733 0.3866183301442396 14.595809418547201 0.0661000545906849 0.021452660883883676 6.086278336001256e-09 8.215648190488302 0.09494542975527387 GVVPLAGTNGETTTQGLDGLSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GVVPLAGTNGETTTQGLDGLSER 23 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8;H3BU78 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ;;; 245.04 3.2966999999999995e-69 19906400.0 76381.0 84756.0 95100.0 82911.0 95672.0 87299.0 88688.0 84406.0 83542.0 76783.0 False True 89310.79470648468 93170.01554710986 97367.54466875858 78265.76547108895 76925.75838719831 82720.8867588937 80286.83059448398 82190.43193554958 84763.64370406384 90703.1500861066 0.9846493161670777 1.027197131066136 1.0734747864470562 0.8628781403599483 0.8481045952006177 0.9119957430405101 0.8851603336627871 0.9061474916529834 0.934517088145183 1.0 16.46886503542659 -5.763641465108727 24.999999936554502 0.899909092083101 1.0283160910755083 0.6095844623952753 0.04429537340910838 35.06189091043616 398061.2944513445 0.012151924219897742 0.019057241915406215 1.7232906627329491e-06 5.763641465108727 0.12840699899240726 GVVPLAGTNGETTTQGLDGLSER ddPTM_PC-9_Lapatinib_30min_R1 4 GVVPLAGTNGETTTQGLDGLSER 23 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8;H3BU78 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ;;; 303.07 5.949199999999999e-160 50715700.0 132238.0 137017.0 140521.0 132551.0 128513.0 141511.0 136316.0 117689.0 132898.0 123647.0 False True 130352.26187052077 136699.74555479965 128967.9058067462 142299.24271717394 120954.11800627914 135458.90440825277 143373.77548068936 123157.26058481779 117929.62776201827 145019.21920072913 0.8988619755985101 0.9426319236044566 0.8893159576885777 0.9812440275258253 0.8340557801435949 0.9340755325730764 0.9886536161957801 0.8492478532403971 0.8131999910907349 1.0 17.14588458576778 -7.805215470945378 24.999624741246482 0.8734179464753367 0.9226095258108222 0.05483745201828372 0.06170884101442241 308.0161897038185 175897.78802791523 0.03210068067914654 0.015420791058971553 1.565973934739539e-08 7.805215470945378 0.04919157933548557 GVVQELQQAISK ddPTM_PC-9_Lapatinib_30min_R1 1 GVVQELQQAISK 12 0 P29692-2;P29692;E9PRY8;A0A087X1X7;E9PK01;P29692-3;E9PI39;E9PQ49;E9PL71;E9PL12;E9PPR1;H0YCK7;E9PIZ1;E9PMW7;E9PN91 P29692-2 EEF1D Elongation factor 1-delta 0 182.08 0.0028638 4925700.0 24436.0 24674.0 24370.0 28549.0 28037.0 26587.0 24690.0 19007.0 25855.0 25294.0 False True 24087.538158986434 24616.868868966034 22366.392670920417 30648.58869667214 26387.91878286283 25449.935987324086 25968.327390902174 19890.13460846491 22942.93763477994 29666.03419786355 0.8119567987527344 0.8297997873520573 0.7539394218230615 1.0331205206686962 0.8894993718022209 0.8578813001286469 0.8753555402013365 0.6704682693953521 0.7733739360562125 1.0 14.856524457514103 -9.534385506187968 9.728889604547694 1.0000000000000064 0.8351837955843521 0.23355938440574375 0.09076280473573821 123613313.21283637 0.0 0.09371264250815874 0.02342816062703969 2.9215578740894065e-10 9.534385506187968 -0.16481620441565437 GVVVLAK ddPTM_PC-9_AZD4547_30min_R2 1 GVVVLAK 7 0 A0A0A0MSS8;P42330;S4R3Z2;P17516;B4DK69;P52895;H0Y804;A0A3B3IRI8;Q04828;P42330-2 A0A0A0MSS8;B4DK69;Q04828;P42330-2 AKR1C3;AKR1C4;AKR1C2;AKR1C1 Aldo-keto reductase family 1 member C3;Aldo-keto reductase family 1 member C4;Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 126.05 2.5926999999999998e-05 0.0 23760.0 23308.0 35305.0 40831.0 35191.0 34186.0 29035.0 43702.0 32375.0 31576.0 False True 31315.18576129861 30841.855187217738 34836.83263212279 31418.043782661534 30305.337090876423 32048.34401577532 31619.058751751953 36948.86007205512 34086.276405127566 30470.5338509864 1.0277202859143495 1.0121862432094972 1.1432957756004343 1.0310959412890122 0.9945784750304061 1.0517815070948566 1.0376929694235852 1.2126095411636182 1.1186635774687654 1.0 14.895127156154869 -7.658412457393621 23.66061526646192 1.1244697456280703 1.0433809651922537 0.19609616800092178 0.060936435857839547 9.440662250501505 2142.3310832634597 0.027973276695811986 0.016150373484209796 2.1957735160437376e-08 7.658412457393621 -0.08108878043581669 GVVVLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GVVVLAK 7 0 A0A0A0MSS8;P42330;S4R3Z2;P17516;B4DK69;P52895;H0Y804;A0A3B3IRI8;Q04828;P42330-2 A0A0A0MSS8;B4DK69;Q04828;P42330-2 AKR1C3;AKR1C4;AKR1C2;AKR1C1 Aldo-keto reductase family 1 member C3;Aldo-keto reductase family 1 member C4;Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 ; 140.79 0.011720999999999999 12528000.0 91120.0 101057.0 94442.0 116393.0 106610.0 93159.0 98410.0 99980.0 92744.0 88736.0 False True 106544.81629796505 111089.27109755376 96693.85545327961 109871.8775611974 85720.53580628842 88273.57804295319 89087.8923732991 97355.63093756637 94100.20554559023 104823.1343662106 1.016424637005602 1.059778185123255 0.9224476642290576 1.0481643983030358 0.817763524479384 0.8421192380544565 0.8498876980921141 0.9287609221590749 0.89770455839301 1.0 16.677597627878278 -6.25472135411598 24.99758081020072 0.8814737834827545 1.0087621812619776 0.5049004783096632 0.059006370530089766 433.32748388215674 1612398.1432574813 0.017393525831524044 0.021945748256089772 5.562610431444967e-07 6.25472135411598 0.12728839777922307 GVVVLAK ddPTM_PC-9_Lapatinib_30min_R1 2 GVVVLAK 7 0 A0A0A0MSS8;P42330;S4R3Z2;P17516;B4DK69;P52895;H0Y804;A0A3B3IRI8;Q04828;P42330-2 A0A0A0MSS8;B4DK69;Q04828;P42330-2 AKR1C3;AKR1C4;AKR1C2;AKR1C1 Aldo-keto reductase family 1 member C3;Aldo-keto reductase family 1 member C4;Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 ; 140.79 0.011720999999999999 66067000.0 95706.0 99491.0 131517.0 123913.0 101969.0 96461.0 110962.0 108490.0 105519.0 98627.0 False True 94341.21488966893 99260.63470220867 120704.17993030108 133025.97538165026 95971.38389876731 92335.58789157355 116707.06941876409 113530.84146221723 93634.33905566992 115674.545537783 0.8155745453856491 0.8581026555214516 1.0434809090378077 1.1500021440602914 0.8296672656251759 0.7982360117543216 1.008926111411813 0.9814677977285369 0.8094636431926673 1.0 16.8197119052901 GWAFGSNS(ph)LPIAGSVGMGVAR ddPTM_PC-9_AZD4547_30min_R2 2 GWAFGSNSLPIAGSVGMGVAR 21 0 M0QZ22;Q5PRF9;A0A087WZT0 M0QZ22 SAMD4B Protein Smaug homolog 2 1 GWAFGS(0.006)NS(0.993)LPIAGS(0.001)VGMGVAR;GWAFGS(0.009)NS(0.99)LPIAGS(0.001)VGMGVAR 87.228 0.00050187 7932700.0 47957.0 45058.0 63382.0 108169.0 79367.0 86460.0 61086.0 85794.0 62759.0 70629.0 True False 63206.32843243252 59622.11734278598 62541.51326693692 83232.30824439062 68348.26202414215 81053.64253214568 66522.53566073765 72536.50864999076 66076.31261496204 68156.30020779432 0.9273732324044824 0.8747851212728772 0.9176189593076636 1.2211975707400884 1.0028164940843705 1.189231843351679 0.9760291485588908 1.0642671099933843 0.9694820935630185 1.0 16.05655940207418 -5.559416897655261 24.996492694167344 1.0630860222039291 0.8998597757775719 0.42926549950415505 0.08139533798687176 138.46413715993626 94725.51894371005 0.021008232312092475 0.036387460771597005 2.757929132205635e-06 5.559416897655261 -0.1632262464263572 GWAFGSNS(ph)LPIAGSVGMGVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GWAFGSNSLPIAGSVGMGVAR 21 0 M0QZ22;Q5PRF9;A0A087WZT0 M0QZ22 SAMD4B Protein Smaug homolog 2 1 GWAFGS(0.043)NS(0.955)LPIAGS(0.003)VGMGVAR;GWAFGS(0.001)NS(0.974)LPIAGS(0.026)VGMGVAR;GWAFGSNS(1)LPIAGSVGMGVAR;GWAFGS(0.048)NS(0.589)LPIAGS(0.363)VGMGVAR 164.69 2.7268e-24 21840000.0 79746.6 84351.5 105897.7 121277.5 127303.0 109807.1 127281.6 99521.5 113056.8 97730.9 True False 93246.12431285437 92725.35946035729 108422.70278726384 114482.71486196025 102358.891002232 104048.62237164813 115224.56540901643 96909.16607674559 114710.04181754772 115448.73853262099 0.8076842198367279 0.8031734312467778 0.9391415113351639 0.9916324449886668 0.8866176651493655 0.9012538698484639 0.998058245361068 0.8394129490584525 0.9936015176565611 1.0 16.81689288381844 -5.261752273136155 24.8965403706091 0.9380760665853253 0.8054288132934312 0.5279168596195781 0.052089689715098295 18.613944453986697 1481243.410277054 0.01282239942946946 0.029662097810349425 5.473280764721835e-06 5.261752273136155 -0.13264725329189408 GWAFGSNS(ph)LPIAGSVGMGVAR ddPTM_PC-9_Lapatinib_30min_R1 3 GWAFGSNSLPIAGSVGMGVAR 21 0 M0QZ22;Q5PRF9;A0A087WZT0 M0QZ22 SAMD4B Protein Smaug homolog 2 1 GWAFGS(0.078)NS(0.919)LPIAGS(0.002)VGMGVAR;GWAFGS(0.008)NS(0.992)LPIAGSVGMGVAR;GWAFGSNS(0.996)LPIAGS(0.003)VGMGVAR 225.69 4.6588e-41 15729300.0 77145.0 65196.0 74686.0 66415.0 63080.0 61238.0 59075.0 55860.0 64639.0 54999.0 True False 76044.89815333963 65045.042667630296 68545.60537629727 71299.38065394522 59369.758420051614 58618.993492750305 62133.61444380502 58455.45952695584 57358.675141154155 64505.50386843907 1.1788900728290643 1.0083642288926482 1.062631888219928 1.105322435731414 0.9203828333957058 0.9087440602325272 0.9632296582091415 0.9062088662415152 0.8892059080437371 1.0 15.97713464186735 -6.2653890368577745 24.998102880998623 0.9270748227710182 1.0811872882357252 0.7060163833240092 0.04965011460841344 186.48369886876145 1180288.7852500747 0.014711204183668019 0.017312797600339873 5.427639109210012e-07 6.2653890368577745 0.15411246546470703 GWAFGSNSLPIAGS(ph)VGMGVAR ddPTM_PC-9_Lapatinib_30min_R1 1 GWAFGSNSLPIAGSVGMGVAR 21 0 M0QZ22;Q5PRF9;A0A087WZT0 M0QZ22 SAMD4B Protein Smaug homolog 2 1 GWAFGSNS(0.052)LPIAGS(0.948)VGMGVAR 154.52 1.4536e-05 7117600.0 37877.0 31462.0 29682.0 28695.0 32355.0 32089.0 26061.0 27968.0 26814.0 22643.0 True False 37336.8670342089 31389.15167201951 27241.6605358334 30805.326023713893 30451.942512377467 30716.628273112517 27410.311062547655 29267.495382203753 23793.924956062256 26556.812380099003 1.4059242690658234 1.1819623237441605 1.025788040595098 1.1599782979526043 1.1466715988548903 1.1566383733663297 1.0321385966897232 1.102071098116281 0.8959631380267917 1.0 14.696794369630084 -1.6344696757471877 0.9578463142431785 1.0692809323360224 199.98098677168232 0.6308663805286706 0.0791912416120446 698.6046597153367 1.474841181573816 0.025938777986672944 304115.6230755486 0.02320226187787264 1.6344696757471877 198.9117058393463 GWAVS(ph)APSCTEIPR ddPTM_PC-9_AZD4547_30min_R2 1 GWAVSAPSCTEIPR 14 0 Q8NCV1-2 Q8NCV1-2 1 GWAVS(0.934)APS(0.013)CT(0.053)EIPR 67.51899999999999 0.034132 9170900.0 4334.5 2448.8 9991.7 8371.4 9415.2 9422.0 9279.8 11905.0 11910.0 4619.1 True False 5712.78083679919 3240.326711106004 9859.203529539194 6441.503066840702 8108.061998181908 8832.840850542181 10105.684222645346 10065.355799684594 12539.538285253102 4457.386714944619 1.2816435284032046 0.7269566044700395 2.2118797762113602 1.445129955909768 1.8190169524662048 1.9816186962032363 2.2671769063167106 2.2581293577103625 2.813204033477921 1.0 12.121982416698682 -5.370016021136478 0.6967085633909992 2.1478011092561964 0.7572860586942266 0.2869622162591513 0.5232616543939499 1.8165325946018327 1.1222887083134794 0.2441661340815344 1.7721055667662076 4.265637825605921e-06 5.370016021136478 -1.39051505056197 GWDAEGS(ph)PFR ddPTM_PC-9_AZD4547_30min_R2 1 GWDAEGSPFR 10 0 Q8IVD9 Q8IVD9 NUDCD3 NudC domain-containing protein 3 1 GWDAEGS(1)PFR 89.266 0.009459 4265000.0 26068.0 28920.0 36302.0 38498.0 28969.0 33033.0 28947.0 41518.0 29595.0 30933.0 True False 34357.08175191635 38267.82443857633 35820.611760694585 29622.880888170843 24947.15439133867 30967.441288045007 31523.22692223051 35102.34708872784 31159.33128061001 29850.045085272435 1.1509892750167945 1.2820022324675517 1.20001868199415 0.9923898206366975 0.8357493035629358 1.037433652096019 1.0560529082009191 1.175956250265324 1.0438621178493146 1.0 14.865445490076375 -5.724421120904535 6.947362553006903 1.0220554036361487 1.219914941730793 0.5195733502614424 0.08398484282733296 0.1691789352628176 23.096263261372517 0.02551397724340196 0.04370562930694526 1.8861615140313012e-06 5.724421120904535 0.1978595380946444 GWDAEGS(ph)PFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GWDAEGSPFR 10 0 Q8IVD9 Q8IVD9 NUDCD3 NudC domain-containing protein 3 1 GWDAEGS(1)PFR;GWDAEGS(1)PFR 104.07 0.0026576 7385600.0 50634.0 62796.0 62698.0 56469.0 63820.0 46218.0 52396.0 44212.0 38420.0 35644.0 True False 59205.33613291447 69029.97187569391 64192.95810348912 53305.22500496809 51314.929135703285 43794.246717861 47432.67156581023 43051.48184648617 38981.81981650098 42105.97504225127 1.4061029598175752 1.639434113719626 1.5245569788865987 1.2659776896623085 1.2187089619516298 1.0400957743863106 1.1265069035502415 1.0224554069413219 0.9258025678632223 1.0 15.36173735279776 -6.186144497041065 1.0758813032645556 1.0140964394506735 1.5574691577849213 0.8808592295835237 0.07874214917872908 0.1623722480573273 0.38995086627073045 0.033787109091233884 0.05568551440891637 6.514116224543818e-07 6.186144497041065 0.5433727183342478 GWDAEGS(ph)PFR ddPTM_PC-9_Lapatinib_30min_R1 1 GWDAEGSPFR 10 0 Q8IVD9 Q8IVD9 NUDCD3 NudC domain-containing protein 3 1 GWDAEGS(1)PFR 107.34 0.0021855999999999998 2864300.0 25877.0 33257.0 34308.0 23634.0 24309.0 24454.0 24945.0 19165.0 22887.0 22084.0 True False 25507.989234739383 33179.99545980399 31487.32867270981 25372.12320071279 22879.192413332825 23408.159425058235 26236.530043177583 20055.475865272252 20309.22504920552 25901.18997491968 0.9848192017215798 1.2810220492545878 1.215671121797849 0.9795736499087808 0.8833259180557698 0.9037484164906916 1.0129468981379859 0.7743071219774892 0.7841039376519419 1.0 14.660730760529932 -5.915343167295244 3.8378957416818107 0.8906243784755081 1.1715967750801226 0.5823277546451351 0.10084198846562062 0.153522275554417 4.386121099563992 0.029734344616054 0.045541988561922965 1.215225384221424e-06 5.915343167295244 0.2809723966046145 GWDEALLTMSK ddPTM_PC-9_Lapatinib_30min_R1 1 GWDEALLTMSK 11 0 Q00688 Q00688 FKBP3 Peptidyl-prolyl cis-trans isomerase FKBP3 0 152.62 1.2991e-07 0.0 16021.0 12055.0 11791.0 11757.0 15329.0 12886.0 13274.0 12060.0 12641.0 13674.0 False True 15792.537602108434 12027.087388156991 10821.58949457623 12621.649000202262 14427.378357973554 12334.895818733148 13961.262769819175 12620.351627194552 11217.237464368722 16037.53268054029 0.9847236427627594 0.7499337727149566 0.674766481237291 0.7870069075848051 0.899600870368266 0.7691267768202358 0.870536824330813 0.7869260115371677 0.6994366083493352 1.0 13.969164584724446 GWENHVEGQK ddPTM_PC-9_Lapatinib_30min_R1 1 GWENHVEGQK 10 0 Q14204 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 79.07 0.016391 2394900.0 52505.0 47530.0 57626.0 52967.0 49271.0 45142.0 46158.0 48363.0 48903.0 35327.0 False True 51756.269071762246 47419.947205234486 52888.2127227928 56862.36987273226 46372.97665051306 43211.38189114165 48547.83538717144 50610.12153781179 43395.029168580295 41433.22487973137 1.249148943197052 1.1444908607254403 1.2764686523028785 1.3723858096440047 1.119221995997665 1.0429162107601269 1.1717126901922725 1.2214864202513391 1.0473485782133414 1.0 15.338500493782357 -6.393529735305601 9.875253364322676 1.1114890536171411 1.2533495945372821 0.48848139464912665 0.07971770387633703 0.38572575585572627 28.873670369395143 0.02559045020279939 0.02901087298008693 4.0408270680269757e-07 6.393529735305601 0.141860540920141 GWLRDPSAS(ph)PGDAGEQAIR ddPTM_PC-9_AZD4547_30min_R2 1 GWLRDPSASPGDAGEQAIR 19 1 P18206;P18206-2 P18206 VCL Vinculin 1 GWLRDPS(0.206)AS(0.794)PGDAGEQAIR 54.412 0.015676 2866200.0 8191.6 6909.1 7618.2 12782.0 10085.0 7758.4 6326.7 10526.0 7734.2 10113.0 True False 10796.35840413525 9142.331460185602 7517.177690356547 9835.307379931412 8684.871829771495 7273.26602152903 6889.764043558082 8899.44856341706 8143.01402231776 9758.94694815763 1.1063036269680173 0.9368153663251096 0.7702857419237941 1.0078246589698079 0.8899394448917557 0.7452920955679684 0.7059946201325323 0.9119271383166159 0.8344152361495377 1.0 13.252509764967131 -4.850359537533657 3.1484230561796336 0.851777438493518 1.1257314234881266 0.38019324735750326 0.0956645473734825 0.31573641728098134 5.07925827022214 0.025014276006951486 0.1972999793912669 1.4113686370632975e-05 4.850359537533657 0.27395398499460866 GWS(ph)QEGPVK ddPTM_PC-9_AZD4547_30min_R2 4 GWSQEGPVK 9 0 Q9C0C2;E9PKK0 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 GWS(1)QEGPVK;GWS(1)QEGPVK;GWS(1)QEGPVK;GWS(1)QEGPVK 133.42 0.00117 128259000.0 168268.0 191023.0 227609.0 309101.0 256234.0 240340.0 274065.0 422155.0 337380.0 294596.0 True False 221773.72380817318 252767.44909163803 224590.75594292153 237842.54001284466 220660.33202079 225311.50180633733 298456.2540657451 356920.64490683324 355213.21802507923 284282.28370804334 0.7801179901732245 0.8891424600740477 0.790027268014968 0.8366421463572732 0.7762014893879465 0.7925625855662932 1.049858788851782 1.2555149067023437 1.249508810017446 1.0 18.11696466841198 -7.426757620089629 3.343343753635971 1.1869245465859661 0.8131010946079227 0.8286682123493484 0.07414495367838585 0.09051974170021122 1.9093218204292124 0.03361334588800861 0.020842782227177965 3.743194378032927e-08 7.426757620089629 -0.37382345197804345 GWS(ph)QEGPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GWSQEGPVK 9 0 Q9C0C2;E9PKK0 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 GWS(1)QEGPVK;GWS(1)QEGPVK;GWS(1)QEGPVK 121.29 0.0016258 80023000.0 189753.0 159965.0 168265.0 215348.0 231347.0 197167.0 199021.0 246213.0 187817.0 164012.0 True False 221874.43510741656 175845.2680281449 172277.0757485659 203282.7497276356 186016.21608833506 186827.21542733352 180168.2900927379 239750.1696342374 190563.46831014482 193746.07728172207 1.1451815604235107 0.9076068558149543 0.8891900066604262 1.0492225317782637 0.9601031344642545 0.9642890222529358 0.9299196795130928 1.2374452840437216 0.9835732985347131 1.0 17.563807575308864 GWS(ph)QEGPVK ddPTM_PC-9_Lapatinib_30min_R1 4 GWSQEGPVK 9 0 Q9C0C2;E9PKK0 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 GWS(1)QEGPVK;GWS(1)QEGPVK;GWS(1)QEGPVK;GWS(1)QEGPVK 142.19 0.00067509 116431000.0 203675.0 273533.0 270164.0 231577.0 334328.0 317780.0 370924.0 293812.0 294773.0 481382.0 True False 200770.55715057987 272899.651144317 247952.15878319787 248607.94509822596 314663.48435413785 304189.2901813609 390128.62977492873 307463.5781334398 261572.56064269925 564588.2372988041 0.355605278124708 0.4833604972890834 0.4391734407530192 0.44033497100055957 0.5573326958769149 0.5387807787790857 0.6909967370936495 0.5445802052208131 0.46329792822846916 1.0 19.106839546250526 -14.52287874522142 0.15904095089564257 2.7955077872147616 0.3751698426408889 0.8007252659712047 0.07688323951175198 59.74565982341953 0.5458382584127294 33.93812073669697 0.3461156230680365 3.0000000004069937e-15 14.52287874522142 -2.420337944573873 GWSQEGPVKS(ph)PAECR ddPTM_PC-9_AZD4547_30min_R2 2 GWSQEGPVKSPAECR 15 1 Q9C0C2;E9PKK0 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 GWS(0.001)QEGPVKS(0.999)PAECR;GWSQEGPVKS(1)PAECR 149.31 0.0001053 34191000.0 32653.0 45262.0 45314.0 41393.0 43209.0 46718.0 44363.0 45167.0 42764.0 47048.0 True False 43035.974775407565 59892.05635334858 44713.1067523584 31850.483365474967 37210.17619163078 43796.71607467943 48311.22105748138 38187.477984406054 45024.41773556369 45400.863840296675 0.9479109236069184 1.3191831892015649 0.9848514537001422 0.7015391486275041 0.819591810466918 0.9646670210668229 1.0641035648004906 0.8411178720901737 0.9917083933456161 1.0 15.470432127423697 -5.511510551047379 24.810773026168736 0.9047713188458958 1.1381646586551817 0.31420826817597947 0.12929641658867871 513.5127499679121 1120725.495274539 0.03440339747145909 0.06547591203389944 3.079565523521043e-06 5.511510551047379 0.2333933398092859 GWSQEGPVKS(ph)PAECR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GWSQEGPVKSPAECR 15 1 Q9C0C2;E9PKK0 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 GWSQEGPVKS(1)PAECR 139.49 3.6063e-06 0.0 5702.8 19158.0 8168.8 17022.0 12317.0 11374.0 15488.0 6438.7 10288.0 7544.0 True False 6668.171404565796 21059.87962918885 8363.575172346516 16068.312526068592 9903.57226832432 10777.527417217347 14020.864516590362 6269.690947366562 10438.442537016197 8911.667481728855 0.7482518191165922 2.3631805913278146 0.9384972217033384 1.8030646407097939 1.111304061628098 1.2093727059850439 1.573315492901484 0.703537352602192 1.1713231624067677 1.0 13.121479687513894 -7.315536457041339 0.7551672926536339 0.964684061478749 1.4789240586198247 0.10427207721007148 0.4622105549381074 1.3423309122091776 1.489710490033039 0.36531604589825634 0.21976392637231604 4.835746687098603e-08 7.315536457041339 0.5142399971410757 GWSQEGPVKS(ph)PAECR ddPTM_PC-9_Lapatinib_30min_R1 2 GWSQEGPVKSPAECR 15 1 Q9C0C2;E9PKK0 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 GWSQEGPVKS(1)PAECR;GWS(0.003)QEGPVKS(0.997)PAECR 166.36 0.00015185 29880000.0 21545.6 31826.0 17238.0 22109.0 31428.0 29997.0 37827.0 34967.0 34411.0 24379.0 True False 21238.355793020855 31752.30885238363 15820.758180604278 23734.969613461933 29579.466829825353 28714.098236422324 39785.49697106753 36591.69447330943 30535.27081610568 28592.8776670244 0.7427848305564092 1.1104971392579677 0.5533111554857609 0.8301007645982763 1.0345047173736823 1.0042395372305504 1.3914478085901565 1.2797485758318725 1.0679327618472416 1.0 14.803368203681606 -6.64182851516808 1.8131392776501345 1.19817778526669 0.8163721958707614 0.47092794953418693 0.1696603348987028 0.2954224120453512 1.9944442807593625 0.06721825753267245 0.06710638323097003 2.2812426620537573e-07 6.64182851516808 -0.38180558939592857 GY(ph)Y(ph)SPGIVSTR ddPTM_PC-9_AZD4547_30min_R2 1 GYYSPGIVSTR 11 0 Q12789;Q12789-3 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 2 GY(0.983)Y(0.835)S(0.183)PGIVSTR 60.06399999999999 0.026492 0.0 0.0 0.0 0.0 0.0 0.0 495.24 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 464.27256451098594 0.0 0.0 0.0 0.0 0.0 GYADS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 3 GYADSPSK 8 0 Q01518-2;Q01518;Q5T0R8;Q5T0S3;Q5T0R7;Q5T0R6;Q5T0R5;Q5T0R4;Q5T0R3;Q5T0R2;Q5T0R1;Q5T0R9 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1;Adenylyl cyclase-associated protein 1 GYADS(0.949)PS(0.051)K;GYADS(0.985)PS(0.015)K;GYADS(0.88)PS(0.12)K 115.7 0.0036225000000000003 307072000.0 779724.0 733884.0 667017.0 801291.0 773594.0 750349.0 681233.0 797892.0 639735.0 733284.0 True False 1027660.0127332812 971097.6511161883 658171.9187588338 616565.7397725414 666193.8263044382 703429.5584125955 741861.417276813 674596.1251341415 673550.0860551131 707611.9503542794 1.452293184447724 1.372359031853532 0.9301311522923087 0.8713331359989697 0.9414677436847916 0.9940894272071157 1.048401481780213 0.9533419055407306 0.9518636389872832 1.0 19.432598887320005 -5.222573021282995 5.107414576251531 0.9594919027475252 1.4251088060973887 0.9370014764808181 0.04684966097599541 0.04601758324321735 3.081023304124491 0.013467649841490507 0.036240548838563244 5.990002156147717e-06 5.222573021282995 0.4656169033498635 GYADS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GYADSPSK 8 0 Q01518-2;Q01518;Q5T0R8;Q5T0S3;Q5T0R7;Q5T0R6;Q5T0R5;Q5T0R4;Q5T0R3;Q5T0R2;Q5T0R1;Q5T0R9 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1;Adenylyl cyclase-associated protein 1 GYADS(0.952)PS(0.048)K;GYADS(0.98)PS(0.02)K;GYADS(0.947)PS(0.052)K;GYADS(0.99)PS(0.01)K 99.788 0.0050921000000000004 293192000.0 496713.0 520502.0 446308.0 490836.0 502947.0 433540.0 485499.0 375219.0 362028.0 311268.0 True False 580796.7003710631 572173.9986821192 456949.6753525159 463336.0502317821 404398.1457852485 410804.399196449 439509.02001162875 365369.89882739313 367321.97461031296 367698.4244038686 1.5795463396740963 1.556095867448322 1.2427294897805068 1.2600980028211055 1.0998092973634013 1.1172318724576153 1.1952975341794927 0.9936672952019019 0.998976199601165 1.0 18.488163469010125 -3.320729813653866 0.35123380816258093 0.9986530119403884 3.281121778614146 0.901547801003574 0.06399720064884491 5.064865879878104 0.2221249878629552 0.05699487878703624 6.0190750373912065 0.0004778264499685296 3.320729813653866 2.2824687666737575 GYADS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 3 GYADSPSK 8 0 Q01518-2;Q01518;Q5T0R8;Q5T0S3;Q5T0R7;Q5T0R6;Q5T0R5;Q5T0R4;Q5T0R3;Q5T0R2;Q5T0R1;Q5T0R9 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1;Adenylyl cyclase-associated protein 1 GYADS(0.997)PS(0.003)K;GYADS(0.99)PS(0.01)K;GYADS(0.932)PS(0.068)K 107.55 0.0038082 341077000.0 482478.0 503022.0 530116.0 544245.0 554477.0 510030.0 495854.0 432638.0 470904.0 387587.0 True False 475597.7752443714 501857.28346458025 486531.90878693765 584270.5928480988 521863.7530037252 488217.20583799994 521526.89388774475 452739.94090266916 417865.8326810444 454580.8965227857 1.046233528250636 1.1039999421520452 1.0702867465583221 1.2852950867872919 1.1480107435125508 1.073994110998741 1.147269711237422 0.9959502134071218 0.9192331571287203 1.0 18.794177531511757 -7.851567332055876 4.466093155713032 0.9594135651665489 1.127222630884989 0.5395900209252839 0.06523974393424638 0.168917026884115 5.962647162168866 0.039487073301029095 0.018247765362488396 1.4074490036657137e-08 7.851567332055876 0.16780906571844023 GYADSPS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 GYADSPSK 8 0 Q01518-2;Q01518;Q5T0R8;Q5T0S3;Q5T0R7;Q5T0R6;Q5T0R5;Q5T0R4;Q5T0R3;Q5T0R2;Q5T0R1;Q5T0R9 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1;Adenylyl cyclase-associated protein 1 GYADS(0.157)PS(0.843)K 85.807 0.012949 138570000.0 60762.0 58433.0 70617.0 66515.0 61109.0 68716.0 61580.0 62786.0 57184.0 59564.0 True False 80083.05207188663 77320.32453040557 69680.5724396719 51180.99439650584 52625.070168121616 64419.177657170134 67060.50070373293 53083.86637874821 60206.62949655023 57478.68248987058 1.39326526988505 1.3452000147016534 1.2122854843089288 0.8904343693946956 0.9155580449742509 1.120749030190848 1.1667021197911234 0.9235400687568497 1.0474601519817437 1.0 15.810739372675348 -5.522427744022719 3.7649759686687743 1.013633518292871 1.3596437051219694 0.7461716240090639 0.08511730536414447 0.11651714703232377 3.6308177245705173 0.025478884957728633 0.05162228138461519 3.003117024504324e-06 5.522427744022719 0.34601018682909834 GYADSPS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GYADSPSK 8 0 Q01518-2;Q01518;Q5T0R8;Q5T0S3;Q5T0R7;Q5T0R6;Q5T0R5;Q5T0R4;Q5T0R3;Q5T0R2;Q5T0R1;Q5T0R9 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1;Adenylyl cyclase-associated protein 1 GYADS(0.277)PS(0.723)K 83.647 0.014759 83373000.0 57205.0 63046.0 49251.0 46657.0 55963.0 46378.0 51183.0 50220.0 47096.0 30452.0 True False 66888.67664974858 69304.79022350143 50425.33062545763 44042.95955403488 44997.45188375688 43945.85603619714 46334.57570716971 48901.778212488374 47784.68990312155 35972.706542100655 1.8594285245527862 1.9265937118851642 1.4017663799203528 1.2243437813746154 1.2508775738376572 1.2216444149056482 1.288048083147206 1.359413369557172 1.3283595952725087 1.0 15.13461508970303 -5.352780466843254 3.4346262551652083 1.2581160851164497 1.9015069969067648 0.878497619273811 0.09550158633604407 0.07127802772276776 1.5761095224192436 0.02486812851808091 0.06011154609401461 4.43832942024964e-06 5.352780466843254 0.6433909117903152 GYADSPS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 GYADSPSK 8 0 Q01518-2;Q01518;Q5T0R8;Q5T0S3;Q5T0R7;Q5T0R6;Q5T0R5;Q5T0R4;Q5T0R3;Q5T0R2;Q5T0R1;Q5T0R9 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1;Adenylyl cyclase-associated protein 1 GYADS(0.225)PS(0.775)K 94.40899999999999 0.0067423000000000005 185550000.0 54071.0 56354.0 63280.0 51986.0 55852.0 50301.0 53027.0 43122.0 52614.0 39571.0 True False 53299.93762459302 56223.515775379434 58077.36266786389 55809.22386021222 52566.895169256866 48149.74348735807 55772.47859689628 45125.60554460059 46688.05727001788 46410.79462495684 1.1484383763584953 1.2114318711782177 1.2513761752450903 1.202505242825588 1.1326437220919647 1.0374686293663702 1.201713503239725 0.9723084017254651 1.0059740982092977 1.0 15.502172778451014 -7.226827221668998 0.6821265377993603 0.9853178563318036 1.2112973351634615 0.6338491255797188 0.05927791040738696 0.47210897751527786 0.4409090969690438 0.05171142947782173 0.03547544838148142 5.9316125902791025e-08 7.226827221668998 0.22597947883165792 GYALVPIIVNSS(ph)TPK ddPTM_PC-9_AZD4547_30min_R2 2 GYALVPIIVNSSTPK 15 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 GYALVPIIVNS(0.051)S(0.474)T(0.474)PK;GYALVPIIVNS(0.044)S(0.478)T(0.478)PK 160.87 1.3000000000000001e-05 6540400.0 59960.0 55112.0 45817.0 51893.0 55983.0 57169.0 44944.0 47633.0 46829.0 55444.0 True False 79026.03275452288 72925.8762261001 45209.43664370403 39929.870588857855 48210.72678692092 53594.21339255427 48943.92893193518 40272.414347448655 49304.28533670171 53502.9224358402 1.4770414242192016 1.363026034952606 0.844990041392943 0.7463119540197282 0.9010858583423066 1.001706279817211 0.9147898227545965 0.7527142913687127 0.9215250885748638 1.0 15.707330076082743 -5.210386415395029 4.574808299317586 0.876590041165601 1.4427877287011315 0.8649280157202718 0.08473009711009569 0.0691548627195431 3.1717517396199204 0.022836357362140413 0.06361626990705105 6.160466277850505e-06 5.210386415395029 0.5661976875355305 GYALVPIIVNSS(ph)TPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GYALVPIIVNSSTPK 15 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 GYALVPIIVNS(0.416)S(0.566)T(0.019)PK 155.14 0.00018763 2545100.0 65870.0 60526.0 45076.0 55774.0 57680.0 50746.0 60602.0 41666.0 39044.0 39135.0 True False 77020.49000819752 66534.62127760117 46150.782791681966 52649.1636017477 46378.0180593445 48084.7904267726 54861.33983951506 40572.3116487762 39614.94463600901 46229.86570751047 1.6660331763776859 1.439212947287277 0.9982893544115216 1.13885607920324 1.0032046892104634 1.0401239478175852 1.1867077483333965 0.8776212309477864 0.8569123883388913 1.0 15.496537551264769 -5.08634238720097 2.338714664743055 1.0152627057660983 1.680452406274348 0.8374334656246838 0.09727352424998255 0.13718735933231532 1.3113778462815056 0.027790379783658864 0.14145341267904413 8.197050540076388e-06 5.08634238720097 0.6651897005082497 GYALVPIIVNSS(ph)TPK ddPTM_PC-9_Lapatinib_30min_R1 2 GYALVPIIVNSSTPK 15 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 GYALVPIIVNS(0.091)S(0.454)T(0.454)PK;GYALVPIIVNS(0.095)S(0.453)T(0.453)PK 157.2 0.00012442 4046800.0 53834.0 49434.0 52314.0 50244.0 44005.0 42525.0 44096.0 41556.0 41167.0 36311.0 True False 53066.31728805349 49319.53861021591 48012.944857879775 53939.1113690706 41416.712417158706 40706.304880616706 46379.07511661493 43486.84346763652 36530.33895227173 42587.30796863378 1.2460594439812365 1.158080680904755 1.1274003253091758 1.2665536738973404 0.9725130418589211 0.9558318386923526 1.0890351451839557 1.0211221498119878 0.8577752549932693 1.0 15.378135916597826 -6.272047758343205 24.819050398398993 0.9877410608671755 1.1914116698660975 0.72094354182934 0.06596013044051682 371.2542653571304 868573.7700777374 0.02074683956176963 0.023761816516217785 5.345055778431542e-07 6.272047758343205 0.20367060899892198 GYALVPIIVNSST(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GYALVPIIVNSSTPK 15 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 GYALVPIIVNS(0.005)S(0.069)T(0.925)PK 216.88 2.1040999999999998e-17 3157200.0 39084.0 31797.0 24452.0 37346.0 29963.0 29099.0 35600.0 22623.0 24466.0 22477.0 True False 45700.14925581291 34953.59602094779 25035.028414726396 35253.62469736564 24091.965241195216 27572.997214138148 32227.710278319777 22029.170221049877 24823.768964875417 26551.902172165905 1.721162911775109 1.316425308978025 0.9428713714142246 1.3277250145310366 0.9073536458887147 1.0384565683976739 1.2137627680815941 0.8296644842320502 0.9349149000291936 1.0 14.696527598622172 -1.5228791508322468 0.7802266606812059 1.0061434792693746 159.70282381937864 0.700417772479661 0.14146515029976603 244.5081471833656 0.9273106339187931 0.051033851900085934 68444.62177660773 0.029999971985479663 1.5228791508322468 158.69668034010925 GYAYVEFENPDEAEK ddPTM_PC-9_Lapatinib_30min_R1 2 GYAYVEFENPDEAEK 15 0 H3BMS0;H3BMM9;H3BTC0;Q15287-3;Q15287-2;Q15287;H3BPG5;H3BV80 H3BMS0 RNPS1 RNA-binding protein with serine-rich domain 1 0 ; 138.94 3.5113e-06 0.0 47859.0 28070.0 40982.0 32193.0 32130.0 30052.0 24273.7 25257.3 31105.0 20339.0 False True 47176.52188373432 28005.00563961566 37612.618155094824 34560.58061269979 30240.176570010444 28766.7460146336 25530.473413873722 26430.846364306875 27601.627349829047 23854.56904998602 1.9776723605812516 1.1739891666427766 1.576746914868993 1.4488033944474066 1.2676890748536984 1.2059218489487011 1.0702550677136917 1.1079993232710428 1.1570792703062989 1.0 14.541978002779485 -1.5228787453085708 0.25182759990050185 1.0113286221592084 5.776503427661553 0.6613799765116739 0.1629140698802207 32.08812338406833 0.43757611988564754 0.20409648017712587 64.92308427009141 0.029999999998049715 1.5228787453085708 4.765174805502345 GYDDRDYYSR ddPTM_PC-9_AZD4547_30min_R2 3 GYDDRDYYSR 10 1 P62995;H7C2L4;P62995-3;H7BXF3 P62995 TRA2B Transformer-2 protein homolog beta 0 ;; 99.68799999999999 0.0055443 268683000.0 158033.0 137727.0 212728.0 301808.0 251909.0 212671.0 174867.0 231423.0 173372.0 196288.0 False True 208284.2067093986 182244.55935172192 209907.08772599383 232230.82848711763 216935.78361585567 199372.64875033553 190429.82423773388 195661.89292149586 182536.08997404683 189416.01686541777 1.099612430649869 0.9621391177347413 1.1081802436756718 1.2260358565776424 1.1452874324244238 1.052564888913233 1.005352279015752 1.0329743817837531 0.9636782200089278 1.0 17.53119880352879 -7.024728891662563 3.7830574738424003 1.0044204890247064 1.1065830940605805 0.3942119720657311 0.06272984414169057 0.2893170673492926 8.94914486620308 0.02752049617288501 0.02212473084908141 9.446503902863163e-08 7.024728891662563 0.10216260503587415 GYDDRDYYSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GYDDRDYYSR 10 1 P62995;H7C2L4;P62995-3;H7BXF3 P62995 TRA2B Transformer-2 protein homolog beta 0 ;;;; 106.88 0.0029198 203821700.0 349348.0 323284.0 402651.0 429922.0 456814.0 430230.0 420297.0 420876.0 407358.0 321012.0 False True 408485.716462483 355377.4990104759 412251.72690242145 405834.8641659303 367304.57596673776 407667.9814233703 380483.4254732286 409828.4509549823 413314.8401043781 379208.9344704068 1.0772048845129754 0.937154868217403 1.0871361126503027 1.070214404976266 0.968607389168469 1.0750484610619966 1.0033609202921385 1.0807457675735883 1.0899396151665117 1.0 18.532633430140024 -7.772670432519371 24.9967103401021 1.0640070158882449 1.0305516272917945 0.04301941445341029 0.052230641668980865 615.2596628592457 1369346.0934074442 0.026981827612517384 0.013139830093965996 1.6878333639769386e-08 7.772670432519371 -0.033455388596450364 GYDDRDYYSR ddPTM_PC-9_Lapatinib_30min_R1 2 GYDDRDYYSR 10 1 P62995;H7C2L4;P62995-3;H7BXF3 P62995 TRA2B Transformer-2 protein homolog beta 0 ; 85.807 0.015125999999999999 123854000.0 202080.0 161983.0 194294.0 152491.0 166137.0 164189.0 143630.0 158615.0 190548.0 129106.0 False True 199198.30214306666 161607.93831570607 178319.89731652857 163705.69683506366 156365.1482979094 157167.0192132529 151066.45861301274 165984.8319525257 169086.4776806051 151421.8000770683 1.315519311233137 1.0672699587077514 1.1776368873291039 1.0811237004958552 1.032646212225222 1.0379418229955033 0.9976533004899248 1.0961752658338848 1.1166587479117678 1.0 17.208213398379947 -1.522878745862597 0.833306973101699 1.0553673900406029 76.21448931464252 0.6574263456867688 0.053149332166044415 391.58193076372737 1.175604973162515 0.01885202838759371 55720.34798259662 0.029999999959778943 1.522878745862597 75.15912192460192 GYDS(ph)EDDTWEPEQHLVNCEEYIHDFNR ddPTM_PC-9_AZD4547_30min_R2 1 GYDSEDDTWEPEQHLVNCEEYIHDFNR 27 0 Q9Y232-2;Q9Y232 Q9Y232-2 CDYL Chromodomain Y-like protein 1 GY(0.029)DS(0.938)EDDT(0.032)WEPEQHLVNCEEYIHDFNR 54.867 0.0036479999999999998 2328700.0 0.0 1165.5 1776.6 1336.7 1785.8 1672.7 0.0 1873.5 1140.8 1292.9 True False 0.0 1542.2250824052805 1753.0411231901817 1028.5444668091313 1537.8724951518038 1568.105804574603 0.0 1583.9936237470888 1201.1003590106407 1247.6359645281318 0.0 1.2361178470745393 1.4050902450966127 0.8243946920832288 1.2326291794044606 1.2568616560902652 0.0 1.2695959949713143 0.962700974610738 1.0 10.284981330414444 -9.816504192179146 15.144665043397657 0.9999986416126547 0.9349076877268807 0.0006821713472495716 0.48756520208606097 0.0 0.0 0.46138742040320224 0.11190288639139201 1.5257936664802196e-10 9.816504192179146 -0.06509095388577402 GYDSGPEGGAAAS(ph)PPPDAELAACHPAAWSR ddPTM_PC-9_AZD4547_30min_R2 2 GYDSGPEGGAAASPPPDAELAACHPAAWSR 30 0 Q9H6K5;Q9H6K5-2 Q9H6K5 PRR36 Proline-rich protein 36 1 GYDSGPEGGAAAS(1)PPPDAELAACHPAAWSR;GYDSGPEGGAAAS(1)PPPDAELAACHPAAWSR 143.04 1.3469e-14 12232600.0 30913.0 35163.0 40452.0 45402.0 38201.0 41867.0 39531.0 51885.0 36517.0 32207.0 True False 40742.69096965587 46528.752100057354 39915.58004913273 34935.27035390756 32897.45054725837 39249.049871539966 43049.18241830566 43867.365448688404 38447.21406906694 31079.44273304783 1.3109208977654154 1.4970909388469102 1.2843081001156156 1.1240636022331152 1.0584955087459593 1.2628620856771384 1.385133664978169 1.4114592023248456 1.2370625303453304 1.0 14.923673015422613 -11.715695143361486 1.5543497583078691 0.42893980052439334 1.286401003262693 0.3263178576245128 0.12315264576888331 306866.88444075896 51508.73382278223 614135.0819883463 0.03863001039305105 1.924442133117968e-12 11.715695143361486 0.8574612027382995 GYDSGPEGGAAAS(ph)PPPDAELAACHPAAWSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GYDSGPEGGAAASPPPDAELAACHPAAWSR 30 0 Q9H6K5;Q9H6K5-2 Q9H6K5 PRR36 Proline-rich protein 36 1 GYDSGPEGGAAAS(1)PPPDAELAACHPAAWSR 147.86 8.474899999999999e-15 5676300.0 8824.4 15006.0 19173.0 14908.0 17368.0 12528.0 15602.0 11773.0 8658.2 14055.0 True False 10318.196630155444 16495.69650880092 19630.157034007403 14072.753092388117 13964.865077231203 11871.009625716451 14124.065611301832 11463.9712245246 8784.809795294876 16603.060240681225 0.6214635422976751 0.9935334974201178 1.1823216171865178 0.8475999537667588 0.8411018736783324 0.7149892522000139 0.8506904996161311 0.6904733861312685 0.5291078673418361 1.0 14.019161560106504 -6.381178422150364 2.25043110192472 0.7446978800063802 0.940680900351865 0.14423420935581677 0.17238986995600786 0.5226162434062412 5.196522169761774 0.06044337448860046 0.07136399074644069 4.157397761242254e-07 6.381178422150364 0.19598302034548487 GYDSGPEGGAAAS(ph)PPPDAELAACHPAAWSR ddPTM_PC-9_Lapatinib_30min_R1 2 GYDSGPEGGAAASPPPDAELAACHPAAWSR 30 0 Q9H6K5;Q9H6K5-2 Q9H6K5 PRR36 Proline-rich protein 36 1 GYDSGPEGGAAAS(1)PPPDAELAACHPAAWSR;GYDSGPEGGAAAS(1)PPPDAELAACHPAAWSR 110.62 1.2271e-15 12747400.0 16309.2 31052.0 37675.0 25285.7 38178.0 46175.0 37325.0 44536.0 41437.0 34431.0 True False 16076.62781725902 30980.10100182921 34577.506929705654 27145.294728622473 35932.44510083594 44200.20288918228 39257.50586737239 46605.3051466614 36769.92870904571 40382.35247357636 0.39811023460751926 0.7671692980764461 0.8562529127625979 0.6722068692353826 0.8898056428076558 1.0945425459822846 0.9721450946440033 1.1541007963108871 0.9105444942343468 1.0 15.301437336853423 -4.558447518849226 0.4657469356181583 1.044683204878624 7.658073718301098e-14 0.7159721009339282 0.1109040052970583 3.381447645636776 0.487179022413389 0.07747545737215024 2.034940149362721 2.7640919182568262e-05 4.558447518849226 -1.0446832048785475 down GYDVIAQAQSGTGK ddPTM_PC-9_Lapatinib_30min_R1 2 GYDVIAQAQSGTGK 14 0 P60842;P60842-2;J3KT12;J3QL43;J3QS69;J3KTB5;J3QR64;Q14240-2;J3KS25;E7EQG2;J3QLN6;J3QKZ9;Q14240;J3KT04;J3KSN7;J3KS93;E7EMV8 P60842 EIF4A1;EIF4A2 Eukaryotic initiation factor 4A-I;Eukaryotic initiation factor 4A-II;Eukaryotic initiation factor 4A-II, N-terminally processed 0 ; 233.37 4.4764e-26 19578600.0 93518.0 101756.0 96762.0 108875.0 98554.0 93419.0 103492.0 97247.0 86022.0 103702.0 False True 92184.41617089897 101520.39023387006 88806.60187212129 116882.03069635299 92757.24748461902 89423.68714032519 108850.30936975502 101765.4506376276 76333.29650818183 121626.7525257708 0.7579287801124719 0.8346879952447919 0.7301568119505991 0.9609894884892821 0.7626385277775563 0.7352304101137429 0.8949536767964872 0.8367028513407451 0.6276028498911701 1.0 16.89210106745572 -10.677165871816918 4.7055933535021035 1.0000190300626108 0.7993539393416449 0.32426290823322235 0.08909061046121589 1.9010842108274317e-05 3.41672402648367e-06 0.08343082822221541 0.02023282856858686 2.1029750887319918e-11 10.677165871816918 -0.20066509072096594 GYEEWLLNEIR ddPTM_PC-9_AZD4547_30min_R2 2 GYEEWLLNEIR 11 0 O43707;O43707-2;P12814-4;P12814-3;P12814;P12814-2;H9KV75;P35609-2;P35609;A0A494C1A0;A0A494C060;F6THM6 O43707;P12814-4 ACTN4;ACTN1;ACTN2 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2 0 ; 133.91 0.0002599 4737700.0 11830.6 11635.2 15829.6 19476.0 14409.900000000001 14729.2 13315.0 14508.8 12360.4 13872.2 False True 15592.484708233142 15396.050861262896 15619.689161123099 14986.10910120046 12409.334117979599 13808.180795564205 14500.009205427146 12266.798339056179 13013.745509743272 13386.538500369057 1.1647883960295835 1.1501144123881195 1.166820620632621 1.1194909797471022 0.9270009657565682 1.0314974849684646 1.0831783888738222 0.9163532707665982 0.9721516514059623 1.0 13.70849533543517 -6.10890240480112 5.02736616600269 0.9915800153201069 1.157284688579121 0.7559112531165746 0.045434240236805215 0.11799703713879914 4.48852294635187 0.014213820097013415 0.018682121279758525 7.782114120329227e-07 6.10890240480112 0.16570467325901417 GYEEWLLNEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GYEEWLLNEIR 11 0 O43707;O43707-2;P12814-4;P12814-3;P12814;P12814-2;H9KV75;P35609-2;P35609;A0A494C1A0;A0A494C060;F6THM6 O43707;P12814-4 ACTN4;ACTN1;ACTN2 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2 0 119.22 0.004543600000000001 1794500.0 4139.8 6097.0 8495.7 8156.1 8100.7 4349.0 8203.4 5478.6 4598.7 4847.4 False True 4840.5863752229625 6702.269866330745 8698.269708121676 7699.140159432967 6513.4259863615125 4120.930784023058 7426.314564527208 5334.792555056523 4665.947287614344 5726.19524800271 0.8453407831162154 1.170457795456501 1.519031281924175 1.3445472649781576 1.1374788501376 0.7196629883447361 1.2969020864451832 0.931646987922267 0.814842506329455 1.0 12.483361147895419 -6.532255406822712 24.884798694301452 0.9652696647653913 1.2381029338123961 0.2653451504813459 0.21079772706801328 272.826660877758 724051.4570042379 0.07192933648677749 0.07202077791930289 2.9359225400238984e-07 6.532255406822712 0.2728332690470048 GYEEWLLNEIR ddPTM_PC-9_Lapatinib_30min_R1 2 GYEEWLLNEIR 11 0 O43707;O43707-2;P12814-4;P12814-3;P12814;P12814-2;H9KV75;P35609-2;P35609;A0A494C1A0;A0A494C060;F6THM6 O43707;P12814-4 ACTN4;ACTN1;ACTN2 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2 0 ; 123.96 0.0024684 7728200.0 6976.2 8263.0 10519.8 7577.7 9418.0 11525.9 9902.0 8392.0 10230.3 8041.7 False True 6876.718108721606 8243.867531177206 9654.902651602326 8134.989336466165 8864.051756500417 11032.964125185194 10414.677109141896 8781.92295650221 9078.055884165118 9431.697130108294 0.7291071812271657 0.8740598237469644 1.0236654674567003 0.862515963378137 0.9398151397593321 1.1697750651858043 1.104220901654665 0.9311073961936452 0.9625050252287825 1.0 13.20330167601768 -3.937498621553366 0.7210784883705662 1.0162074761112823 5.930747591392115e-11 0.5176540080256551 0.08273327520405147 7.642666121467168 1.234356766873783 0.035885771789633696 8.374140393858022 0.00011547856499625217 3.937498621553366 -1.0162074760519748 GYESPTLSKDY(ph)EGYPAPAMPDFQPGDTTVR ddPTM_PC-9_AZD4547_30min_R2 1 GYESPTLSKDYEGYPAPAMPDFQPGDTTVR 30 1 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 GY(0.008)ES(0.165)PT(0.165)LS(0.165)KDY(0.372)EGY(0.124)PAPAMPDFQPGDTTVR 52.739 0.0036631 5491900.0 6322.1 5539.0 8840.3 16438.0 11467.0 10260.0 8417.2 7693.1 5858.9 10616.0 True False 8332.39629215092 7329.3734289513895 8723.07184585059 12648.473064568354 9875.004984827929 9618.440578068656 9166.314493722974 6504.3081648512025 6168.58949281859 10244.337071258913 0.8133660806152059 0.71545609813195 0.8515018380568206 1.234679508941031 0.9639476831090255 0.9389031726663655 0.8947689274535494 0.6349174299525364 0.6021462833475998 1.0 13.322539007631958 -10.610256170377456 5.215812308955493 1.0000024614984588 0.8583304625386394 0.06167628061600605 0.17281161763851946 5.494549872661169e-06 9.616403990232523e-07 0.18586111894069204 0.04507715947619807 2.45326142253232e-11 10.610256170377456 -0.1416719989598194 GYESPTLSKDY(ph)EGYPAPAMPDFQPGDTTVR ddPTM_PC-9_Lapatinib_30min_R1 1 GYESPTLSKDYEGYPAPAMPDFQPGDTTVR 30 1 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 GY(0.013)ES(0.207)PT(0.147)LS(0.147)KDY(0.379)EGY(0.107)PAPAMPDFQPGDTTVR 67.848 7.4676e-05 4222000.0 54376.0 21119.0 34501.0 24104.0 26675.0 30728.0 20807.0 18468.0 34900.0 18815.0 True False 53600.58826866289 21070.100253047494 31664.46095771133 25876.688568586826 25106.028945067817 29413.835070466575 21884.28465056709 19326.090700748653 30969.194486707398 22067.14768058839 2.428976732494215 0.9548175667298425 1.4349140820571624 1.1726340414782985 1.1377106506226273 1.3329241955606606 0.9917133363736829 0.8757856239730095 1.4034072248471783 1.0 14.429612543693237 -4.756037788646132 24.999995850680786 1.1517937849841051 2.428978740785683 0.8133067340879014 0.18454130745234912 69.25289518941572 320486.578800347 0.044737255661353253 0.37576893879388606 1.7537279005791078e-05 4.756037788646132 1.2771849558015778 GYFEYIEENK ddPTM_PC-9_AZD4547_30min_R2 2 GYFEYIEENK 10 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1W2PRI6 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 ; 192.92 0.003406 4544100.0 14555.6 16308.5 16046.0 18350.6 20127.6 20889.0 20472.1 24347.0 18997.5 15611.5 False True 19183.978024712047 21579.903694900484 15833.219555729844 14120.152683943785 17333.230167665708 19582.807527804674 22294.07724028727 20584.730588401577 20001.669065835067 15064.946136770775 1.273418295063629 1.4324580718033826 1.0509974222266785 0.9372853082746229 1.150567018979143 1.2998923029672589 1.479864384371844 1.3663992158696152 1.3276960225576018 1.0 13.878907894277205 -6.822906508214346 5.334047792859426 1.3318556106627062 1.1641759529852753 0.10547416030820966 0.1679256012597296 0.3779894333181076 21.16640682911793 0.06290236009458776 0.05606918895422098 1.5034655864898653e-07 6.822906508214346 -0.16767965767743087 GYFEYIEENK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GYFEYIEENK 10 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1W2PRI6 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 ; 155.42 0.0012758 3762900.0 18416.9 26530.0 19997.6 23461.0 27890.0 17824.8 23444.0 16486.1 15430.7 19267.699999999997 False True 21534.51741964437 29163.723069338143 20474.41862532032 22146.556231588256 22425.154710040188 16890.03610923295 21223.214600138464 16053.357343466841 15656.344795483661 22760.781486970707 0.9461238152992107 1.2813146633841535 0.8995481388475521 0.9730138767100742 0.9852541628624374 0.7420674953055354 0.9324466566443504 0.7053078275302851 0.6878649928802337 1.0 14.474262472695772 -6.193021452341786 0.8644816820766488 0.7938142351836638 1.0966826053356944 0.35736827241370683 0.13334543500799867 0.6289478053853529 0.9953570006846306 0.06483992454233937 0.11685380870235546 6.411779042802135e-07 6.193021452341786 0.3028683701520306 GYFEYIEENK ddPTM_PC-9_Lapatinib_30min_R1 3 GYFEYIEENK 10 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1W2PRI6 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 ;; 179.0 0.003406 17702300.0 55722.0 59388.0 57275.0 58822.0 52299.0 44722.6 56111.0 57556.0 46671.5 54650.0 False True 54927.39406183667 59250.49073478784 52566.070587893606 63147.966104439765 49222.87564379013 42809.9186514725 59016.15302676844 60230.26187850826 41414.86419731706 64096.17968345231 0.8569526972294302 0.9243997228447067 0.8201123818533068 0.9852063947696192 0.7679533458450096 0.667901251882641 0.9207436904699738 0.9396856751207886 0.646136234668743 1.0 15.967950750184622 -6.283423279932002 24.984103736459673 0.8177795644733116 0.8931804279503405 0.08825860600068258 0.11365272158746821 2050.4144896329826 2330233.268438513 0.034890668496876186 0.039595639067737484 5.206869823682051e-07 6.283423279932002 0.0754008634770289 GYFEYIEENKYSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GYFEYIEENKYSR 13 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1W2PRI6 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 112.5 0.0011757999999999998 0.0 10631.0 9669.6 19185.0 18123.0 22322.0 16152.0 16785.0 19665.0 15506.0 13098.0 False True 12430.618328178974 10629.533983839881 19642.44315951766 17107.62706555875 17948.164339817762 15304.960686029055 15195.00328712353 19148.8145867898 15732.745915530048 15472.563716289054 0.8033974560461747 0.6869924195335143 1.2695015202192175 1.1056750115398362 1.1599993814161818 0.9891677272536579 0.9820611222383712 1.2375980437314662 1.0168157135437794 1.0 13.917424642550746 -5.2499394045833 24.999315344629178 1.0984627456060119 0.7451948944225323 0.6595265749891528 0.10053987499405971 422.2282060049302 917860.1854461608 0.025287060883628178 0.06566572405039259 5.624197919580739e-06 5.2499394045833 -0.3532678511834796 GYFVQPTVFSNVTDEMR ddPTM_PC-9_Lapatinib_30min_R1 3 GYFVQPTVFSNVTDEMR 17 0 P00352 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ;; 124.42 0.00054172 100972300.0 247918.0 214083.0 270725.0 226528.0 259878.0 289975.0 243211.0 224969.0 233708.0 231566.0 False True 244382.64385740744 213587.30396672036 248467.03552872062 243187.6247952554 244592.48697980618 277573.44521474006 255803.27553943716 235421.8810297117 207385.34398565642 271591.8745577004 0.899815741009909 0.7864274449099661 0.9148544518622302 0.8954156864644695 0.9005883823959611 1.0220241149216298 0.9418664529490225 0.86682225457999 0.7635918575376851 1.0 18.05108079234543 -4.398594179321527 21.353134636368384 0.8971349312639401 2.114391033163609 0.0 0.07714730181548192 69334.06179032337 6528882.2278700145 0.01921864988909793 1871123.4952385302 3.993979401159794e-05 4.398594179321527 1.217256101899669 GYGFVDFDS(ph)PSAAQK ddPTM_PC-9_Lapatinib_30min_R1 1 GYGFVDFDSPSAAQK 15 0 F8W1T6;Q15434 F8W1T6 RBMS2 RNA-binding motif, single-stranded-interacting protein 2 1 GYGFVDFDS(0.967)PS(0.033)AAQK 157.38 2.9247e-05 3257600.0 49926.0 40916.0 42553.0 37620.0 47923.0 40083.0 36513.0 35756.0 42710.0 31237.0 True False 49214.046084692935 40821.26151587156 39054.456599330195 40386.70029664109 45104.263360243116 38368.74352803669 38403.4644805189 37417.35429369552 37899.55004376141 36636.27382931382 1.3433147244716588 1.1142307131466302 1.0660051505587753 1.102369211585225 1.2311367572581522 1.0472883707222613 1.0482360913513835 1.0213198664258465 1.0344815692865796 1.0 15.16098515805701 -2.426874264968154 1.2737103376399113 1.0715701972677703 129.76646733213005 0.6414861160961133 0.060972763057294876 467.63254939059084 2.178027708339944 0.019089863584298025 174839.9019766644 0.0037421891480757777 2.426874264968154 128.6948971348623 GYGFVHFETQEAAER ddPTM_PC-9_AZD4547_30min_R2 2 GYGFVHFETQEAAER 15 0 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YAR2;H0YBN4;E5RGH3 A0A087WTT1 PABPC1 Polyadenylate-binding protein;Polyadenylate-binding protein 1 0 ; 116.58 0.00011929 4053600.0 47792.0 43799.0 67866.0 107537.0 79869.0 71525.0 49119.0 77898.0 51317.0 57174.0 False True 62988.86186464578 57956.170213872916 66966.05249714336 82746.00608008809 68780.56798929293 67052.53044311519 53490.49584388852 65860.6540179613 54029.51185426809 55172.35566241118 1.1416743241862333 1.050456691907363 1.2137609803521079 1.4997729403905584 1.2466491082988687 1.2153283947743045 0.969516258671034 1.1937256118072919 0.9792859341526773 1.0 15.751657959257825 -7.168512842275954 6.609833413982999 1.0522589091169317 1.233732776374974 0.37110816600343755 0.12185624906722872 0.32052011663722124 19.24756241850632 0.050954596152999576 0.039352550762689745 6.784020595588911e-08 7.168512842275954 0.18147386725804227 GYGFVHFETQEAAER ddPTM_PC-9_Lapatinib_30min_R1 1 GYGFVHFETQEAAER 15 0 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YAR2;H0YBN4;E5RGH3 A0A087WTT1 PABPC1 Polyadenylate-binding protein;Polyadenylate-binding protein 1 0 76.156 0.011948 7627200.0 29448.0 25653.0 36290.0 25662.0 29047.0 38339.0 30009.0 29678.0 34587.0 36341.0 False True 29028.066119898194 25593.602054615636 33306.37628345104 27549.269085922486 27338.51256859922 36699.33034257412 31562.719184835285 31056.94822486565 30691.44784274352 42622.49342866132 0.6810503981538159 0.6004717226938516 0.7814272137597259 0.6463551723465595 0.6414104471470351 0.8610319901626357 0.7405178966749764 0.7286516045065897 0.720076311211422 1.0 15.379327373231824 -14.522878743514541 0.16479479822078685 2.0896667412138523 0.6398429652213897 0.6375451609720405 0.06755850418539239 86.79174066203821 0.8056078807136245 30.919249506847045 0.26968782391628804 3.0000000121976906e-15 14.522878743514541 -1.4498237759924626 GYIFLEYAS(ph)PAHAVDAVK ddPTM_PC-9_AZD4547_30min_R2 2 GYIFLEYASPAHAVDAVK 18 0 P55884;P55884-2;C9JZG1 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 1 GYIFLEYAS(1)PAHAVDAVK;GYIFLEY(0.006)AS(0.994)PAHAVDAVK 127.67 2.4366e-05 21310200.0 97981.0 88199.0 105308.0 123534.0 108497.0 101667.0 99373.0 126433.0 90171.0 98396.0 True False 129136.9198685945 116707.60192455011 103911.54711297507 95055.14488127417 93434.06434454332 95309.74641817814 108217.00448899074 106895.68499130831 94937.25497225508 94951.18598941149 1.360034827611266 1.2291326401922436 1.0943680800844635 1.0010948667020787 0.9840220885178059 1.0037762606652079 1.139711983176899 1.1257962065184612 0.9998532823259525 1.0 16.53489840004383 -5.075767943039102 1.9055392702421634 1.0423042154420463 1.37564807575287 0.8016778225849482 0.05244777141779746 0.22080150637692775 1.2662916941541298 0.016315698282156482 0.10598798755844402 8.399086557868278e-06 5.075767943039102 0.33334386031082364 GYIFLEYAS(ph)PAHAVDAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GYIFLEYASPAHAVDAVK 18 0 P55884;P55884-2;C9JZG1 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 1 GYIFLEY(0.001)AS(0.999)PAHAVDAVK;GYIFLEY(0.003)AS(0.997)PAHAVDAVK 130.73 2.333e-05 14431000.0 93624.0 94377.0 90802.0 99659.0 99661.0 96995.0 95667.0 93574.0 81863.0 76940.0 True False 109472.69404171087 103746.12484413573 92967.0640485025 94075.42932883724 80133.14247247465 91908.41145006128 86604.7291908996 91117.78164984818 83060.09150541943 90888.6129432951 1.20447095072306 1.1414644968656564 1.02286811337416 1.035062878421639 0.8816631685475195 1.0112203110350295 0.9528666615798373 1.0025214237420046 0.9138668620373838 1.0 16.471811936022775 -5.180276245631124 1.2238070894782707 0.9642716709281137 1.2404795702898659 0.7898155049422078 0.042166623183232096 0.3358112275434449 0.6836926856489237 0.012668809211875302 0.09846965218125232 6.602733283609801e-06 5.180276245631124 0.27620789936175216 GYISPYFINTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GYISPYFINTSK 12 0 P10809;E7ESH4 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 158.05 1.3803999999999999e-11 0.0 9993.6 9178.9 9266.6 11588.0 14903.0 10737.0 11800.0 10960.0 13249.0 9475.3 False True 11685.319097402817 10090.120530763208 9487.5508877762 10938.761928802893 11982.864132080646 10173.932818591751 10682.21857539813 10672.311613079897 13442.741560354556 11193.096883566468 1.0439755162451083 0.9014592329293037 0.8476251913539385 0.9772775169008868 1.070558421563714 0.908947088051115 0.954357733745841 0.9534726380103812 1.2009850089023157 1.0 13.450321633060135 -8.230706113236891 23.507095737144763 1.1004924704759158 0.9544414705041477 0.3591396757211551 0.07648920715038096 295.52636046540715 226041.35246135562 0.05128053503913369 0.019375079255845532 5.878870406939727e-09 8.230706113236891 -0.14605099997176807 GYISPYFINTSK ddPTM_PC-9_Lapatinib_30min_R1 2 GYISPYFINTSK 12 0 P10809;E7ESH4 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 ; 202.31 6.4434e-06 13755500.0 73092.0 69897.0 80832.0 60320.0 65842.0 62258.0 72160.0 53411.0 83411.0 59599.0 False True 72049.69467656883 69735.1577909588 74186.30498054311 64756.134021621256 61969.303010352625 59595.370470486436 75896.09171840834 55892.670046441795 74016.3748232307 69900.60773932432 1.0307448963141919 0.997633068528066 1.0613113015726723 0.9264030187421545 0.8865345383183308 0.852572994683129 1.0857715572580224 0.7996020614710334 1.0588802761094014 1.0 16.09301737847917 -5.771422457490242 24.992105793886534 0.9355739253376396 1.0266700880065571 0.17125078333672084 0.08475892076172689 308.3398103302273 771912.7589962214 0.022490739726791994 0.03381121327097383 1.6926904443347527e-06 5.771422457490242 0.09109616266891751 GYIWNYGAIPQTWEDPGHNDK ddPTM_PC-9_AZD4547_30min_R2 1 GYIWNYGAIPQTWEDPGHNDK 21 0 Q15181;Q5SQT6 Q15181 PPA1 Inorganic pyrophosphatase 0 120.11 7.787899999999999e-05 0.0 12397.0 12369.0 12895.0 15351.0 19382.0 14342.0 12286.0 17602.0 12747.0 16301.0 False True 16338.988126381259 16367.037361021808 12724.00387455667 11812.064120585752 16691.14385767289 13445.192472773937 13379.43019886428 14882.015353720984 13420.780396483739 15730.306951638244 1.0386948059319099 1.0404779392634327 0.8088846526438266 0.7509112286811146 1.0610818917258686 0.8547317299090389 0.8505511202037205 0.9460727879929315 0.8531798163726247 1.0 13.941259202450896 -5.240743385503502 23.466754283221178 0.8871281631134529 1.0395864862795168 0.3214096108268344 0.08642512107150867 425.03971965558253 481938.71448597085 0.02179926689815843 0.05748860960582936 5.744557944980336e-06 5.240743385503502 0.1524583231660639 GYLDDPTVPR ddPTM_PC-9_AZD4547_30min_R2 1 GYLDDPTVPR 10 0 P11413;P11413-2;P11413-3;E7EUI8 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 90.601 0.039652999999999994 3956700.0 68123.0 55990.0 67401.0 81326.0 70694.0 73146.0 64024.0 65807.0 62165.0 57618.0 False True 89784.69695357502 74087.67255587452 66507.21870096902 62577.54717417488 60879.358367264795 68572.16905686252 69722.0119690774 55638.04024442203 65450.9149876372 55600.81135755428 1.6148091144964254 1.3324926515808568 1.1961555430059911 1.1254790289255858 1.0949365104722224 1.233294395937729 1.2539747220721902 1.000669574525241 1.1771575520137554 1.0 15.762818315249659 -4.640672371286958 1.280485285848552 1.1336140802100454 1.9541866231531944 0.7792207533182438 0.0800741115196021 0.8650257294724085 0.9890999490702224 0.023804807781070306 1.0180025075544301 2.2873236936329758e-05 4.640672371286958 0.820572542943149 GYLDDPTVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GYLDDPTVPR 10 0 P11413;P11413-2;P11413-3;E7EUI8 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 104.06 0.012254000000000001 3992200.0 52180.0 57385.0 48528.0 64111.0 67121.0 61266.0 64991.0 45048.0 46126.0 57887.0 False True 61013.04339802265 63081.80355574707 49685.09156346486 60519.06852066638 53969.121882130115 58053.103107370975 58834.58198590678 43865.537732301374 46800.5054881813 68381.45486676013 0.8922454708941967 0.9224987049289998 0.726587225444022 0.8850216573862979 0.7892362335268801 0.848959754080785 0.8603879823929567 0.6414829549586577 0.6844034772201195 1.0 16.06131749706676 -7.705594315666065 24.999966809720394 0.7472046984363063 0.8441199271091835 0.07178464194814393 0.103088851363088 149.51833064393452 66933.87295247498 0.04629329414281688 0.026727417613500056 1.9697253958022883e-08 7.705594315666065 0.09691522867287716 GYLDDPTVPR ddPTM_PC-9_Lapatinib_30min_R1 1 GYLDDPTVPR 10 0 P11413;P11413-2;P11413-3;E7EUI8 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 126.24 0.0016249000000000003 22512000.0 85342.0 111570.0 133030.0 114690.0 110550.0 128950.0 109860.0 105470.0 101970.0 102100.0 False True 84125.00743019395 111311.66651984022 122092.78691065016 123124.68519462446 104047.66634966253 123435.10909713159 115548.01325089167 110370.5212371649 90485.06480829671 119747.84896030152 0.7025179004099091 0.9295504469290464 1.019582297057595 1.0281995565151438 0.8688896481485536 1.0307918694894675 0.9649276730573911 0.9216910549579445 0.755629980779814 1.0 16.86964021539052 -4.766059723384844 4.917673173831611 0.9509268303420134 0.6868625476287964 0.45163636575678945 0.08087977688765059 0.16062572849621315 9.935375193469245 0.020433874995869978 0.1465975294625234 1.7137216234321575e-05 4.766059723384844 -0.264064282713217 GYLGPEQLPDCLK ddPTM_PC-9_AZD4547_30min_R2 1 GYLGPEQLPDCLK 13 0 P40926;P40926-2 P40926 MDH2 Malate dehydrogenase, mitochondrial 0 131.37 0.00077048 0.0 6951.6 8949.6 8278.7 10146.0 8700.6 8315.8 7057.7 8960.3 9597.2 8596.0 False True 9162.064197737522 11842.383181033283 8168.919028793511 7806.996454137394 7492.671873288042 7795.811711413577 7685.821627423444 7575.691522210321 10104.488398927882 8295.056656418772 1.1045209909021962 1.4276434353066854 0.9847936388080417 0.9411625233561589 0.9032695234806094 0.9398141609293439 0.9265544463130462 0.9132778516163839 1.2181337412697428 1.0 13.01803611968955 -5.33741856482101 8.369177003774105 0.9674091848640894 1.2653720862856148 0.5097337493493572 0.11248304211978018 0.22042198148867959 22.40916817797296 0.02814947407976596 0.05886333037808401 4.598132006781567e-06 5.33741856482101 0.2979629014215254 GYLGPEQLPDCLK ddPTM_PC-9_Lapatinib_30min_R1 2 GYLGPEQLPDCLK 13 0 P40926;P40926-2 P40926 MDH2 Malate dehydrogenase, mitochondrial 0 ; 186.02 1.5170999999999998e-35 4938800.0 48566.0 41870.0 53758.0 43485.0 45284.0 39948.0 43308.0 36886.0 52495.0 45119.0 False True 47873.439934086404 41773.05258748513 49338.224751880975 46683.031961707544 42620.48415176949 38239.517163336306 45550.27633232857 38599.85821896335 46582.4603031434 52917.75903271157 0.9046762525316505 0.7893957217965855 0.9323566540560065 0.8821808182173781 0.8054098459729421 0.7226216276410764 0.8607748545090746 0.7294310818245822 0.8802802906742149 1.0 15.691464347045683 -4.731834849735208 23.765357344268942 0.835628993640441 0.9046770026832548 0.03522291457084714 0.08262358579609089 6146.703468557923 4933831.234014162 0.019970294401979005 2.0253178810344505 1.8542366046231686e-05 4.731834849735208 0.06904800904281383 GYLPSHYER ddPTM_PC-9_AZD4547_30min_R2 2 GYLPSHYER 9 0 Q6P2Q9;I3L1T8 Q6P2Q9 PRPF8 Pre-mRNA-processing-splicing factor 8 0 ; 136.57 0.00083458 4178500.0 17347.4 16347.3 24204.0 32872.0 25912.0 23379.0 21942.7 28445.0 22031.6 22904.0 False True 22863.51235166463 21631.24503612513 23883.039145387356 25293.8682673373 22314.566073677626 21917.107434178062 23895.557791357573 24049.478851073374 23196.14539759715 22102.137931435027 1.0344479987678807 0.9786946902254119 1.0805759705000946 1.1444082172414098 1.00961120335515 0.9916283891707235 1.0811423702759466 1.0881064504112392 1.049497811911044 1.0 14.431898307261118 GYLPSHYER ddPTM_PC-9_Lapatinib_30min_R1 2 GYLPSHYER 9 0 Q6P2Q9;I3L1T8 Q6P2Q9 PRPF8 Pre-mRNA-processing-splicing factor 8 0 ; 155.84 6.9067e-05 4127000.0 32924.0 28969.0 30860.0 29883.0 30397.0 27658.0 26848.0 25864.0 32097.0 23959.4 False True 32454.49772247784 28901.924060350066 28322.8099230449 32080.695506765696 28609.108222801337 26475.131813947024 28238.0580717271 27065.73586117411 28481.897863605966 28100.75036610626 1.1549334910865177 1.0285107580333563 1.0079022643184106 1.141631276346978 1.0180905438492573 0.9421503507564704 1.0048862647378434 0.9631677271443779 1.0135636056878905 1.0 14.778321034373114 -6.514161984001536 24.263122209253694 0.9833110311439787 1.0746917705556136 0.5009296254543867 0.046121947236741394 250.01604115304167 695923.0271151437 0.014584125400519373 0.015327672960349894 3.0608215895636615e-07 6.514161984001536 0.09138073941163494 GYNHGQGSYSYSNSY(ph)NSPGGGGGSDYNYESK ddPTM_PC-9_AZD4547_30min_R2 1 GYNHGQGSYSYSNSYNSPGGGGGSDYNYESK 31 0 Q12906-7;Q12906 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 GYNHGQGSYSY(0.001)S(0.003)NS(0.314)Y(0.676)NS(0.007)PGGGGGSDYNYESK 149.91 7.1368e-16 17019000.0 9809.5 14462.0 54519.0 96217.0 71958.0 67092.0 32963.0 83522.0 43994.0 62014.0 True False 12928.716949724692 19136.558680176026 53796.04243791824 74035.65718783144 61967.87378549308 62896.72663389691 35896.64314220764 70615.59404462457 46319.433024468926 59842.908735592544 0.21604426026228782 0.3197798884530866 0.8989543385266994 1.2371667546266436 1.0355090535336342 1.0510305725912694 0.5998479001214981 1.1800160710207055 0.7740170724174658 1.0 15.86889268038374 -5.261836203881384 3.8938591821398263 0.9850896665281452 0.24204435920890818 0.7257336459009063 0.17419721680257347 0.1042727018174164 3.681287515636539 0.04572524247410999 0.12052333115045757 5.4722231133667985e-06 5.261836203881384 -0.743045307319237 down GYNHGQGSYSYSNSYNS(ph)PGGGGGSDYNYESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GYNHGQGSYSYSNSYNSPGGGGGSDYNYESK 31 0 Q12906-7;Q12906 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 GYNHGQGSYSYSNS(0.01)Y(0.135)NS(0.855)PGGGGGSDYNYESK 135.47 5.124199999999999e-19 0.0 2342.1 7661.1 14113.0 19198.0 19448.0 15831.0 14642.0 14223.0 11555.0 8018.6 True False 2738.5712714164206 8421.64337755396 14449.507443850553 18122.39830075578 15637.304008636127 15000.79449111726 13255.003761099946 13849.661320514175 11723.97001508769 9472.308704797331 0.2891133890124852 0.8890803330014728 1.5254472688936411 1.9131976021408104 1.6508440018130408 1.5836471296084322 1.3993424596040496 1.4621209836098243 1.237709874167212 1.0 13.20950038417021 -4.98880056057516 2.508729842885052 1.511590622395648 0.25234075782305143 0.7193952827444038 0.2339737259704162 0.17839072800824016 1.9243120854938163 0.06382006285941981 0.3985602022881651 1.0261230407015907e-05 4.98880056057516 -1.2592498645725965 GYPHWPAR ddPTM_PC-9_AZD4547_30min_R2 2 GYPHWPAR 8 0 P51858;H3BPQ6;M0R0J3;Q9Y3E1;O75475-3;O75475-2;O75475;Q7Z4V5-2;Q7Z4V5;Q7Z4V5-4;Q7Z4V5-3 P51858;O75475-3;Q7Z4V5-2 HDGF;HDGFRP3;HDGFRP2;PSIP1 Hepatoma-derived growth factor;Hepatoma-derived growth factor-related protein 3;PC4 and SFRS1-interacting protein;Hepatoma-derived growth factor-related protein 2 0 ; 119.57 0.0028988000000000004 17315800.0 115990.0 124565.0 153688.0 194951.0 162670.0 142138.0 134127.0 175156.0 141556.0 137573.0 False True 152872.40725812368 164828.20024866026 151649.99670204488 150008.05891292522 140086.07838858993 133250.0883904016 146064.04316157143 148089.66488446467 149038.36116769823 132756.61114396193 1.1515238747119576 1.2415818604311897 1.1423159675083516 1.129947937208609 1.0552098097523739 1.0037171576028296 1.1002393169194329 1.115497477740491 1.1226436098619623 1.0 17.018424181998192 -5.811915412865863 1.9938826015233275 1.071675237655382 1.1940498567818134 0.5516837619925085 0.04591488506966816 0.25575019390425463 2.076716562472268 0.014660806475626701 0.027581514635329447 1.5420007577634504e-06 5.811915412865863 0.12237461912643144 GYPHWPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GYPHWPAR 8 0 P51858;H3BPQ6;M0R0J3;Q9Y3E1;O75475-3;O75475-2;O75475;Q7Z4V5-2;Q7Z4V5;Q7Z4V5-4;Q7Z4V5-3 P51858;O75475-3;Q7Z4V5-2 HDGF;HDGFRP3;HDGFRP2;PSIP1 Hepatoma-derived growth factor;Hepatoma-derived growth factor-related protein 3;PC4 and SFRS1-interacting protein;Hepatoma-derived growth factor-related protein 2 0 ; 73.616 0.023852 4312200.0 69694.0 85894.0 92518.0 93860.0 104016.0 67589.0 90551.0 85812.0 76787.0 65445.0 False True 81491.81768075471 94420.98866632987 94723.9799964689 88601.32849822588 83634.81148510368 64044.51385636564 81973.3537475319 83559.52592532942 77909.86460826817 77309.66043766498 1.054096179176234 1.2213349293192384 1.2252541203805332 1.1460576595038263 1.0818157913465252 0.8284154075156613 1.0603248453487553 1.0808419730766212 1.0077636373928602 1.0 16.238361080823815 -6.40640073884264 3.7513942774034312 1.0008853654599088 1.170166883192537 0.49526237879932844 0.07799666445751093 0.20959106891409243 5.259232247550995 0.02604357834526628 0.02952935523258074 3.9228279516861296e-07 6.40640073884264 0.16928151773262812 GYPHWPAR ddPTM_PC-9_Lapatinib_30min_R1 2 GYPHWPAR 8 0 P51858;H3BPQ6;M0R0J3;Q9Y3E1;O75475-3;O75475-2;O75475;Q7Z4V5-2;Q7Z4V5;Q7Z4V5-4;Q7Z4V5-3 P51858;O75475-3;Q7Z4V5-2 HDGF;HDGFRP3;HDGFRP2;PSIP1 Hepatoma-derived growth factor;Hepatoma-derived growth factor-related protein 3;PC4 and SFRS1-interacting protein;Hepatoma-derived growth factor-related protein 2 0 ; 115.46 0.0016344999999999999 7526300.0 140454.0 168667.0 170724.0 164478.0 188091.0 181308.0 167469.0 174984.0 179673.0 152840.0 False True 138451.10020389117 168276.4619243693 156687.73173369822 176574.2608025238 177027.857181134 173553.87948959117 176139.7253878896 183114.3954504988 159436.33469943222 179258.1903535015 0.7723557843067713 0.9387379265210924 0.8740896659991167 0.9850275764488923 0.9875579845586456 0.9681782413809863 0.9826035007970224 1.0215120162118827 0.8894228731474969 1.0 17.451679511982867 -3.7219228994543276 0.7786847228088848 0.9767028358833014 1.2388393264453253e-15 0.6471142843324873 0.042883464837094445 6.995339648955109 0.9343260272861302 0.015067341538048385 8.710478398290011 0.0001897042674380118 3.7219228994543276 -0.9767028358833002 GYS(ph)ENMRK ddPTM_PC-9_AZD4547_30min_R2 1 GYSENMRK 8 1 Q8WY54-3;Q8WY54 Q8WY54-3 PPM1E Protein phosphatase 1E 1 GYS(1)ENMRK 50.473 0.041654000000000004 12296000.0 29648.0 41360.0 33587.0 33206.0 29033.0 39792.0 35835.0 41806.0 31967.0 28520.0 True False 39075.44728329046 54728.81116111747 33141.61443464405 25550.869727585872 25002.269096059088 37303.799949562155 39024.24557840643 35345.84330630947 33656.71035807605 27521.52348081239 1.419814106967345 1.9885821800262478 1.2042071165773183 0.9283959060405784 0.9084623935695387 1.3554409506279632 1.417953682891631 1.284298208671191 1.2229232288518121 1.0 14.748272713593016 -5.334933955884408 8.525554796810992 1.1725504171504153 1.7030396741383722 0.5191396895625305 0.20744859248726719 0.2627992056500772 28.405663551014076 0.05712050378211399 0.11940992374811052 4.6245134204336405e-06 5.334933955884408 0.5304892569879569 GYS(ph)ENMRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GYSENMRK 8 1 Q8WY54-3;Q8WY54 Q8WY54-3 PPM1E Protein phosphatase 1E 1 GYS(1)ENMRK 53.327 0.037074 0.0 14806.0 21363.0 15953.0 15354.0 18967.0 8398.2 16417.0 10217.0 13164.0 10907.0 True False 17312.363368170245 23483.777456851512 16333.3800220894 14493.765158339633 15250.552505748752 7957.783607813849 14861.862911212807 9948.814575806327 13356.498596158754 12884.3527602355 1.3436734999681745 1.8226586848296038 1.2676911542268934 1.1249121650154754 1.1836490966636652 0.6176316153321773 1.1534815281587465 0.7721625417235536 1.0366449013551087 1.0 13.653332445419712 -5.765982722645807 1.4162571629149991 0.9349779156847304 1.5904000270098693 0.6010322721770054 0.1961114555558148 0.26779942059730444 1.0783845818564655 0.062129183961887595 0.14644266309710705 1.7140254945053788e-06 5.765982722645807 0.6554221113251388 GYS(ph)FSLTTFSPSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GYSFSLTTFSPSGK 14 0 P25787;A0A024RA52;H3BT36 P25787 PSMA2 Proteasome subunit alpha type-2;Proteasome subunit alpha type 1 GYS(0.885)FS(0.099)LT(0.013)T(0.003)FSPSGK;GYS(0.973)FS(0.019)LT(0.004)T(0.004)FSPSGK 176.4 0.00010258 10885200.0 36806.0 40004.0 40048.0 46975.0 50529.0 45080.0 42777.0 47812.0 43590.0 33585.0 True False 43036.52884836375 43975.33274277437 41002.89620288577 44343.143045004814 40628.2051754615 42715.92544119551 38724.85288133948 46556.98566100147 44227.42128582192 39673.69464128628 1.0847623151179357 1.1084254476519464 1.0335033470821813 1.1176963337026669 1.024059028099236 1.076681308040904 0.9760838568596686 1.173497605452458 1.1147794952224293 1.0 15.275895135299914 -11.14041021736126 2.637394960705909 0.9923963881946722 1.0776003867580066 0.16465771120381922 0.053202821952212494 10896552.134012206 10019586.332988558 570195.2587387116 0.012982886456543236 7.2375200963568014e-12 11.14041021736126 0.08520399856333438 GYS(ph)FSLTTFSPSGK ddPTM_PC-9_Lapatinib_30min_R1 1 GYSFSLTTFSPSGK 14 0 P25787;A0A024RA52;H3BT36 P25787 PSMA2 Proteasome subunit alpha type-2;Proteasome subunit alpha type 1 GYS(0.999)FSLTTFSPSGK 127.32 2.9149e-05 4830000.0 16752.0 15381.0 19212.0 16033.0 17105.0 17687.0 17063.0 14370.0 18974.0 12236.0 True False 16513.11340805945 15345.386239505831 17632.463520464626 17212.12030452011 16098.917529723883 16930.56824041076 17946.438650099793 15037.682660264158 16836.94831492224 14350.976296554856 1.1506613255311169 1.0692921458723124 1.2286595111091874 1.1993692936871556 1.1217994648620975 1.1797502755596614 1.250537822601524 1.0478508464872982 1.1732266827702986 1.0 13.808861266296196 -9.266814047157412 0.7952108056094237 0.9980031257729626 1.163442635479862 0.3738966237117318 0.06117839315997323 3.252357831291041 2.6276315305133884 0.07940442615907499 0.02078096392652701 5.409859085128514e-10 9.266814047157412 0.16543950970689936 GYS(ph)FTTTAER ddPTM_PC-9_AZD4547_30min_R2 2 GYSFTTTAER 10 0 P60709;A0A2R8Y793;A0A2R8YEA7;P63261;I3L3I0;I3L1U9;I3L4N8 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 GYS(0.489)FT(0.489)T(0.022)TAER;GYS(0.43)FT(0.43)T(0.137)T(0.004)AER 155.0 0.00013383 44056000.0 56231.0 52691.0 73140.0 95093.0 73045.0 73335.0 49764.0 83298.0 62413.0 52661.0 True False 74111.28832254137 69722.3353213355 72170.11581117305 73170.77802220444 62903.96259847888 68749.35085698495 54192.89959435796 70426.20809761685 65712.02376133516 50817.35441876094 1.4583854112480261 1.3720182036000512 1.4201864035749374 1.4398777515893464 1.2378441049905535 1.3528715070535788 1.066425047391897 1.3858692350898267 1.2931020221917604 1.0 15.633033649346784 -6.265125706422979 24.16872666117858 1.2406750667700082 1.4188291416349106 0.4215183493240152 0.11354047595359144 214.77131609930095 1408107.579829562 0.033251066766026134 0.03918503684988233 5.430931105824667e-07 6.265125706422979 0.17815407486490242 GYS(ph)FTTTAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GYSFTTTAER 10 0 P60709;A0A2R8Y793;A0A2R8YEA7;P63261;I3L3I0;I3L1U9;I3L4N8 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 GYS(0.493)FT(0.493)T(0.011)T(0.003)AER;GYS(0.734)FT(0.263)T(0.003)TAER;GYS(0.942)FT(0.055)T(0.003)T(0.001)AER;GYS(0.909)FT(0.091)TTAER 138.76 0.00011981 31127800.0 75682.0 66627.0 95205.0 85990.0 80556.0 76838.0 96191.0 79151.0 66907.0 53550.5 True False 88493.46781236405 73241.288237497 97475.04826697336 81172.25908334144 64771.63007608454 72808.48001443177 87079.0921174679 77073.37011741672 67885.38829939178 63258.78174447526 1.3989119830005685 1.1578042797811796 1.5408935420335754 1.283177716118927 1.0239152302635264 1.1509624119625184 1.3765534162388924 1.2183821438222364 1.0731377751409288 1.0 15.948978151842823 -5.36164492269802 0.032641601127816666 1.4327364817758393e-07 2.6070534784012525 0.3422210083369084 0.13582877309093624 607.4959181168849 3.795330137849858 123.87516972234644 182.30209689799565 4.348656231300356e-06 5.36164492269802 2.6070533351276044 GYS(ph)FTTTAER ddPTM_PC-9_Lapatinib_30min_R1 2 GYSFTTTAER 10 0 P60709;A0A2R8Y793;A0A2R8YEA7;P63261;I3L3I0;I3L1U9;I3L4N8 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 GYS(0.487)FT(0.487)T(0.007)T(0.019)AER;GYS(0.457)FT(0.457)T(0.087)TAER 143.24 0.00012842 16902000.0 48155.0 67244.0 94076.0 55601.0 82075.0 71829.0 70414.0 58456.0 79883.0 59490.0 True False 47468.300869454564 67088.3006494589 86341.43442386162 59690.08301949874 77247.50986565846 68757.04111157717 74059.69238165201 61172.079164119736 70885.73533471773 69772.7672345578 0.6803270495188839 0.961525582379807 1.237466103839687 0.8554925565562892 1.1071298004559935 0.9854423700931049 1.0614412372764677 0.8767328800142783 1.0159513251985322 1.0 16.09037643257536 -4.784330289161052 4.482035011750814 1.0158860189178411 0.6591733787370044 0.48701648982037005 0.10306795966408276 0.15121732104075408 6.498830430931933 0.02456681772026669 0.16614181066560516 1.6431216228658004e-05 4.784330289161052 -0.3567126401808367 GYSDRDGYGR ddPTM_PC-9_AZD4547_30min_R2 2 GYSDRDGYGR 10 1 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71 P38159 RBMX RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed 0 ; 91.265 0.010606 26497700.0 32710.0 22128.0 59909.0 117546.0 84375.0 57720.0 38707.0 53508.0 30359.0 55246.0 False True 43111.09958973388 29280.443263375415 59114.567516154784 90447.58576759636 72660.98766851462 54110.75927545051 42151.8480146052 45239.568091518115 31963.7147608731 53311.854355573676 0.8086587891352662 0.5492295028434738 1.1088447068803646 1.6965754964053357 1.3629424177198597 1.0149855023715435 0.7906655756797604 0.8485836525172077 0.5995611135130463 1.0 15.702168744024412 -7.158199597552844 4.096969858716276 0.7968519438804766 1.1133212005072748 0.17635117794972066 0.29977812624011657 0.46428962861614526 13.609462086116272 0.13737474839885785 0.10419721987337895 6.9470496451099e-08 7.158199597552844 0.31646925662679815 GYSDRDGYGR ddPTM_PC-9_Lapatinib_30min_R1 1 GYSDRDGYGR 10 1 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71 P38159 RBMX RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed 0 89.029 0.012458 9765100.0 132340.0 30858.0 52953.0 37041.0 33529.0 40303.0 23184.0 22301.0 51212.0 25876.0 False True 130452.8073318163 30786.550196909877 48599.40874449113 39765.11870515373 31556.890140550255 38579.33464088173 24384.354079816785 23337.185873803104 45443.96527373239 30348.63212239729 4.298474040137781 1.0144295819576463 1.6013706498694142 1.3102771335716008 1.0398126022049368 1.2712050574566154 0.8034745678643332 0.7689699416989625 1.4973974804022467 1.0 14.889343872152098 -4.759972642260243 24.999985447823477 1.1473723600882497 4.298477887357383 0.9290959066569099 0.2613275623996446 9.127984219190427 155529.68514872235 0.0671672505254426 0.4110496024549008 1.7379103023951716e-05 4.759972642260243 3.1511055272691335 GYSFSLTTFS(ph)PSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 GYSFSLTTFSPSGK 14 0 P25787;A0A024RA52;H3BT36 P25787 PSMA2 Proteasome subunit alpha type-2;Proteasome subunit alpha type 1 GYSFSLT(0.003)T(0.016)FS(0.961)PS(0.02)GK;GYSFSLT(0.001)T(0.003)FS(0.965)PS(0.032)GK 156.17 0.00020003 6538100.0 35066.0 27393.0 24942.0 37201.0 38644.0 42432.0 33250.0 38180.0 38099.0 29743.0 True False 41001.98121493027 30112.39600596985 25536.711873061737 35116.74857726926 31071.98560827513 40206.7912227331 30100.319290846415 37177.81545505386 38656.12579877333 35135.170454541556 1.166978292249337 0.8570442555538402 0.7268133765311183 0.999475685558545 0.884355624472537 1.1443459844531931 0.8567005340073898 1.0581367608036827 1.1002117052139322 1.0 15.100628277209688 -6.722095557672381 24.99993925285634 1.024564271255979 0.9159630076965062 0.1426869133695382 0.1265741233577091 316.696859245161 201235.3116990303 0.0418708859916667 0.04187028158377199 1.8962886355388246e-07 6.722095557672381 -0.10860126355947286 GYSFSLTTFS(ph)PSGK ddPTM_PC-9_Lapatinib_30min_R1 1 GYSFSLTTFSPSGK 14 0 P25787;A0A024RA52;H3BT36 P25787 PSMA2 Proteasome subunit alpha type-2;Proteasome subunit alpha type 1 GYSFS(0.002)LT(0.018)T(0.018)FS(0.949)PS(0.013)GK 88.78 0.0055823 4907100.0 17808.0 14000.0 19269.0 14161.0 13653.0 17544.0 11982.0 15364.0 21157.0 12696.0 True False 17554.054654412772 13967.583860157432 17684.777200490993 15202.447179711182 12849.957382830762 16793.68401706148 12602.369331623724 16077.867529039562 18774.07586691314 14890.486683643383 1.1788771601196362 0.9380206407558376 1.1876560905102604 1.0209503223565202 0.8629642305073841 1.1278129703785094 0.8463369666397093 1.079740902404518 1.2608100907498025 1.0 13.862103287573175 -10.428036722168848 5.923623502414015 0.9999999849041996 1.0462644190241106 0.011022672254575983 0.13315625957552235 2.599575903666131e-08 4.734137434293665e-09 0.12546332584763661 0.030429316178084455 3.732185986200475e-11 10.428036722168848 0.04626443411991099 GYSFT(ph)TTAER ddPTM_PC-9_AZD4547_30min_R2 1 GYSFTTTAER 10 0 P60709;A0A2R8Y793;A0A2R8YEA7;P63261;I3L3I0;I3L1U9;I3L4N8 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 GYS(0.004)FT(0.927)T(0.069)TAER 141.08 0.00030386 9095100.0 27889.0 21516.0 32909.0 48246.0 31507.0 37484.0 29259.0 52803.0 36682.0 34984.0 True False 36757.12187276332 28470.6262316877 32472.605157641392 37123.63009326954 27132.796900407564 35140.11955441767 31862.99431780645 44643.50964222979 38620.93563221275 33759.22080830086 1.0888024365694282 0.8433437013655014 0.9618884672141749 1.0996589732942361 0.803715140656802 1.040904342963309 0.9438308573156358 1.3224093617484398 1.1440114643498072 1.0 15.042993985342973 -7.737252215507944 24.970886160427423 1.1749078590796027 0.9652284976329246 0.34953772349074774 0.11566524285755839 202.65825705908767 209225.14925190064 0.05146324720410041 0.02969366732460993 1.8312506189724575e-08 7.737252215507944 -0.2096793614466781 GYSFT(ph)TTAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GYSFTTTAER 10 0 P60709;A0A2R8Y793;A0A2R8YEA7;P63261;I3L3I0;I3L1U9;I3L4N8 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 GYS(0.296)FT(0.683)T(0.02)T(0.001)AER 99.75200000000001 0.010397 7874100.0 16297.0 15322.0 22496.0 19623.0 24661.0 16500.0 21568.0 16572.0 15526.0 14460.0 True False 19055.760219577907 16843.06690042967 23032.38995655508 18523.586928624365 19828.854080469744 15634.710953410082 19524.92290120228 16137.002559485416 15753.038377693776 17081.483534702988 1.1155799307983965 0.9860423929930355 1.3483834650405009 1.0844249500338528 1.1608391062863572 0.9153017020826311 1.1430460862216778 0.9447073216270266 0.9222289355423771 1.0 14.060145658677278 -6.747979054271434 24.985410340057747 0.9914753434495046 1.1391478232755121 0.3555837607027671 0.10347584242715846 278.8915578334078 517684.9695697913 0.034098398032531105 0.033915035600682 1.786573738014964e-07 6.747979054271434 0.1476724798260075 GYSFT(ph)TTAER ddPTM_PC-9_Lapatinib_30min_R1 1 GYSFTTTAER 10 0 P60709;A0A2R8Y793;A0A2R8YEA7;P63261;I3L3I0;I3L1U9;I3L4N8 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 GYS(0.031)FT(0.632)T(0.328)T(0.008)AER 123.62 0.001076 11639000.0 20552.0 33625.0 28592.0 25778.0 30575.0 31664.0 34347.0 27489.0 35893.0 22223.0 True False 20258.92471122479 33547.143378413864 26241.276128311718 27673.800112887126 28776.6386127628 30309.804532389117 36125.3195988383 28766.239293528262 31850.35236995383 26064.21593971382 0.7772696772495827 1.2870958196482087 1.0067932290389028 1.0617545594656004 1.1040669199228081 1.1628895571804378 1.3860121356573962 1.1036679315450804 1.2219954148485903 1.0 14.669782841175293 -6.6377922022965405 2.687052310656967 1.1957394135542945 1.0512625115914174 0.16118488846466694 0.14732011788223048 0.49487096472758935 7.24575345158605 0.05073765662530652 0.05056577118849474 2.3025432561173263e-07 6.6377922022965405 -0.1444769019628771 GYSFTTTAER ddPTM_PC-9_AZD4547_30min_R2 4 GYSFTTTAER 10 0 P60709;A0A2R8Y793;A0A2R8YEA7;P63261;I3L3I0;I3L1U9;I3L4N8 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ;;; 203.29 0.00039946 320961000.0 128411.0 135029.0 165473.0 222277.0 192109.0 194973.0 162795.0 197614.0 153596.0 169329.0 False True 169243.0268852746 178674.48361398774 163278.71990186264 171034.4717954165 165437.98139271903 182781.30748808742 177283.43962429638 167077.29701796523 161714.7709875512 163400.84324973647 1.035753693306277 1.093473448854285 0.9992526149471139 1.0467171918691573 1.0124671213591538 1.1186068801905171 1.0849603716753298 1.022499600951323 0.9896813735556533 1.0 17.31805590314118 -7.982901019779927 5.969813078481051 0.9979830019247463 1.0555862896008505 0.34059706436338966 0.03443121070181027 0.18695952610669941 23.66129751434489 0.02105603468250714 0.009398850866470677 1.0401572014388458e-08 7.982901019779927 0.05760328767610423 GYSFTTTAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GYSFTTTAER 10 0 P60709;A0A2R8Y793;A0A2R8YEA7;P63261;I3L3I0;I3L1U9;I3L4N8 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ;;;; 181.41 0.0005761 258706700.0 172862.3 185979.3 200016.0 184995.0 224946.0 196858.0 222566.0 197001.0 166753.0 154360.0 False True 202124.47320394826 204442.0958096254 204785.14000490448 174630.3299118822 180869.44608837186 186534.41993129693 201482.93724169958 191829.932489813 169191.44715931814 182344.24608691232 1.1084773857224315 1.1211875350987517 1.1230688349074418 0.957695861862549 0.9919120014467716 1.0229794684192415 1.1049591175235933 1.05202076076686 0.9278683083790588 1.0 17.476305150267414 -5.74247851524955 24.996220889354795 1.0143407473579267 1.1179389407011027 0.5393823058450469 0.04607312589391945 211.28772512312668 278539.656818366 0.01338052233216939 0.023126477680811504 1.809345417200976e-06 5.74247851524955 0.10359819334317599 GYSFTTTAER ddPTM_PC-9_Lapatinib_30min_R1 4 GYSFTTTAER 10 0 P60709;A0A2R8Y793;A0A2R8YEA7;P63261;I3L3I0;I3L1U9;I3L4N8 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ;;; 200.6 0.0017959 852580000.0 219990.0 196489.0 244243.0 214589.0 235628.0 230709.0 196989.0 201069.0 199802.0 192523.0 False True 216852.9022587745 196034.0417927478 224162.28334524515 230370.59090791896 221768.8243024717 220842.11387894646 207188.1265454204 210411.39977847273 177298.19475166505 225800.34402922794 0.9603745432323377 0.8681742387751759 0.9927455350388183 1.0202402122031287 0.9821456440020553 0.9780415296903193 0.9175722359333591 0.9318471177848903 0.7851989575742865 1.0 17.78468815863844 -7.573282607241693 2.2297364176158734 0.891519299094184 0.9663035068217747 0.16758297398282707 0.06189253769305336 0.5133641458414773 5.092628107620544 0.03661640993916625 0.018456346535608188 2.671267576442983e-08 7.573282607241693 0.07478420772759065 GYT(ph)SDDDTWEPEIHLEDCK ddPTM_PC-9_AZD4547_30min_R2 2 GYTSDDDTWEPEIHLEDCK 19 0 Q99549-2;Q99549 Q99549-2 MPHOSPH8 M-phase phosphoprotein 8 1 GYT(0.485)S(0.485)DDDT(0.03)WEPEIHLEDCK;GY(0.001)T(0.49)S(0.49)DDDT(0.02)WEPEIHLEDCK 120.41 0.00074663 0.0 18522.0 24102.1 24364.0 22752.0 21942.0 24945.0 25686.9 25626.0 25233.8 23339.1 True False 24411.610718466876 31892.632482745845 24040.91744084521 17506.877914895922 18895.73204648946 23385.185206620114 27972.98433788107 21666.090526897737 26567.607152176297 22522.00521286917 1.0839004115192183 1.4160654072010541 1.0674412519498098 0.7773232334078503 0.8389897732415209 1.03832607201679 1.2420290322061192 0.9619965150579771 1.1796288519192533 1.0 14.4590476608697 -5.504495612036476 23.813592073706527 1.001576408751015 1.247925626877695 0.2929257132319959 0.1497794662650671 493.2908179713842 639008.4116700465 0.041321828553169876 0.08340473383758677 3.129712092948926e-06 5.504495612036476 0.24634921812667998 GYT(ph)SDDDTWEPEIHLEDCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GYTSDDDTWEPEIHLEDCK 19 0 Q99549-2;Q99549 Q99549-2 MPHOSPH8 M-phase phosphoprotein 8 1 GY(0.003)T(0.824)S(0.143)DDDT(0.03)WEPEIHLEDCK 85.932 0.0026536 2375900.0 14392.0 16659.0 16469.0 14574.0 16677.0 13800.0 16696.0 14132.0 10600.0 11309.0 True False 16828.281345042964 18312.795424504486 16861.683419030305 13757.466029545501 13409.261566846197 13076.303706488423 15114.43401142772 13761.049974091706 10755.004946770188 13359.232178005255 1.2596742927149045 1.3707970024396174 1.2621745916499238 1.0298096362301346 1.0037449299611179 0.9788215020334291 1.131384933657508 1.0300779109706624 0.8050616085913465 1.0 13.705549470833198 -5.737120572045646 3.493947305972203 1.0002026660443906 1.3163458401359756 0.7532533406552074 0.07935599571894401 0.11292851018400465 2.8785988329364485 0.02300418128647061 0.040054831518157086 1.8318057922995107e-06 5.737120572045646 0.316143174091585 GYT(ph)SDDDTWEPEIHLEDCK ddPTM_PC-9_Lapatinib_30min_R1 1 GYTSDDDTWEPEIHLEDCK 19 0 Q99549-2;Q99549 Q99549-2 MPHOSPH8 M-phase phosphoprotein 8 1 GY(0.016)T(0.762)S(0.141)DDDT(0.081)WEPEIHLEDCK 103.92 0.00056428 1392900.0 9537.8 17544.0 17849.0 16583.0 19748.0 19022.0 18895.0 18394.0 16423.0 14369.0 True False 9401.789222981695 17503.37794590014 16381.524119132477 17802.56913926634 18586.461466061817 18208.47340244777 19873.290646054957 19248.652390598385 14573.268798143139 16852.662504511 0.5578815347702532 1.038612025916674 0.9720436824001897 1.0563653745810833 1.102879824543257 1.0804508425641262 1.1792374433853057 1.1421727804402444 0.864745780925849 1.0 14.040688916274663 -4.758709180419102 5.307816946135252 1.0592758718275195 0.529636905155625 0.7484089853501367 0.08521168430767265 0.08097874246287956 6.695421273307592 0.021661724709854054 0.15893278777320285 1.742973642039821e-05 4.758709180419102 -0.5296389666718945 GYT(ph)SDSEVYTDHGRPGK ddPTM_PC-9_AZD4547_30min_R2 2 GYTSDSEVYTDHGRPGK 17 1 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 GYT(0.844)S(0.155)DS(0.001)EVYTDHGRPGK;GYT(0.83)S(0.167)DS(0.003)EVYTDHGRPGK 135.23 1.5774000000000002e-05 263000000.0 386270.0 386980.0 543420.0 664320.0 547750.0 508910.0 446910.0 571980.0 439880.0 500540.0 True False 509095.8250848828 512063.7171936461 536213.8957356793 511171.287641686 471704.3673532315 477087.777249993 486684.1242206119 483593.63379282574 463131.15876718104 483016.2469525188 1.0539931695815765 1.060137667054464 1.1101363548717025 1.0582900489720688 0.9765807471888222 0.9877261484682345 1.007593693361734 1.0011953776792184 0.9588314299761174 1.0 18.881712191455655 -6.175760582636626 4.788651953113794 0.98968315722539 1.0745644761511464 0.815680771038926 0.019157786186855534 0.09399020823792996 3.752166229902932 0.0058729561079324715 0.007644779179561462 6.671744670265006e-07 6.175760582636626 0.08488131892575634 GYT(ph)SDSEVYTDHGRPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GYTSDSEVYTDHGRPGK 17 1 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 GY(0.005)T(0.97)S(0.025)DSEVYTDHGRPGK;GY(0.001)T(0.84)S(0.133)DS(0.026)EVYTDHGRPGK;GYT(0.826)S(0.173)DS(0.001)EVYTDHGRPGK;GYT(0.461)S(0.461)DS(0.079)EVYTDHGRPGK;GYT(0.49)S(0.49)DS(0.019)EVYTDHGRPGK 118.5 6.9681e-05 136225900.0 361762.0 367271.0 392518.0 488293.0 478519.0 421027.0 437422.0 410573.0 440817.0 362867.0 True False 423001.16147480696 403731.23767051904 401877.1177528054 460935.52627726557 384756.6370273842 398947.6029443262 395986.2214989666 399795.8937880532 447263.11468117003 428651.9146464075 0.9868173849724623 0.9418626719620619 0.9375372044804968 1.0753142830529256 0.8975969169407951 0.9307029534054824 0.9237943608058147 0.9326819270545952 1.043417979481358 1.0 18.70944706189247 -8.260665506817011 24.99663772758054 1.021708992593691 0.9528577161614983 0.25187288473555425 0.047162879091410474 97.5290121745401 3150514.8854611954 0.036920089697053564 0.012104201232358234 5.486994099626969e-09 8.260665506817011 -0.0688512764321928 GYT(ph)SDSEVYTDHGRPGK ddPTM_PC-9_Lapatinib_30min_R1 2 GYTSDSEVYTDHGRPGK 17 1 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 GYT(0.845)S(0.155)DSEVYTDHGRPGK;GY(0.001)T(0.769)S(0.224)DS(0.007)EVYTDHGRPGK 131.82 1.5774000000000002e-05 324720000.0 345100.0 290520.0 325890.0 268190.0 312630.0 281930.0 274210.0 260520.0 318260.0 233182.0 True False 340178.8107164105 289847.3187894952 299096.5821717786 287913.58725561365 294241.7180542284 269872.51111092954 288407.2520801654 272624.7102750191 282414.2073736243 273487.19800451514 1.243856433494903 1.0598204263466473 1.0936401570315575 1.0527497789891442 1.0758884518220506 0.9867829758761654 1.05455485369887 0.9968463323483179 1.0326414158843435 1.0 18.061113776165172 -1.5228787452803456 0.7395265572828428 1.0263214077570988 34.02913989430103 0.7865733177377482 0.03232750369482375 155.90748080664346 0.7034120188231361 0.01172824586330253 8559.787264765791 0.029999999999999444 1.5228787452803456 33.00281848654393 GYTLVEYETYK ddPTM_PC-9_Lapatinib_30min_R1 2 GYTLVEYETYK 11 0 Q9Y5S9;Q9Y5S9-2;A0A0J9YW13 Q9Y5S9 RBM8A RNA-binding protein 8A 0 ; 198.87 0.00034405 8916500.0 52574.0 42971.0 51266.0 52475.0 48578.0 48489.0 47227.0 45443.0 45121.0 42027.0 False True 51824.2851191092 42871.50328963039 47051.10737248279 56334.18655146843 45720.73754802265 46415.238503379755 49672.18297651428 47554.447677827695 40038.99783480586 49291.31095254256 1.051387843366661 0.8697578226496525 0.9545517549286399 1.142882700070743 0.9275618088559737 0.9416515326214011 1.0077269607281987 0.9647632971988286 0.812293222904037 1.0 15.589045731010636 -8.023503121605334 24.399789545334773 0.9002738012023204 0.981980619536136 0.12490215450886932 0.0818472688450351 1128.4780762680195 1171521.544809797 0.05349398868143558 0.020517992527758554 9.4732037536647e-09 8.023503121605334 0.08170681833381566 GYTS(ph)DDDTWEPEIHLEDCK ddPTM_PC-9_AZD4547_30min_R2 4 GYTSDDDTWEPEIHLEDCK 19 0 Q99549-2;Q99549 Q99549-2 MPHOSPH8 M-phase phosphoprotein 8 1 GYT(0.178)S(0.817)DDDT(0.005)WEPEIHLEDCK;GYT(0.127)S(0.832)DDDT(0.04)WEPEIHLEDCK;GY(0.139)T(0.16)S(0.603)DDDT(0.098)WEPEIHLEDCK;GYT(0.188)S(0.769)DDDT(0.042)WEPEIHLEDCK 161.47 2.4372e-06 12373300.0 40728.7 51444.0 50459.4 45873.5 47716.4 60577.3 54824.2 61996.1 51730.2 49043.2 True False 53679.57939041259 68072.26695774971 49790.27538641376 35298.07331350994 41091.8015050182 56789.39185476008 59703.44759145163 52416.027273651955 54464.55276270362 47326.21249558826 1.1342462571966136 1.4383628726700959 1.0520654994535048 0.7458461485123159 0.8682672738463652 1.1999564059780607 1.2615302269755302 1.1075474775958072 1.150832696949514 1.0 15.530351847738633 -5.293406080651973 21.31411891207229 1.047902797959222 1.2863042867263303 0.26231644443415914 0.15967831725646223 141.4574024615478 94317.95512475759 0.04652920003660338 0.09689550085246204 5.088548513181972e-06 5.293406080651973 0.23840148876710843 GYTS(ph)DDDTWEPEIHLEDCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GYTSDDDTWEPEIHLEDCK 19 0 Q99549-2;Q99549 Q99549-2 MPHOSPH8 M-phase phosphoprotein 8 1 GY(0.075)T(0.086)S(0.42)DDDT(0.42)WEPEIHLEDCK 69.111 0.027569999999999997 0.0 5548.3 8301.7 4757.0 5011.3 6695.0 5113.0 6206.4 4730.0 5264.2 3313.7 True False 6487.517606079896 9125.83791197605 4870.424921022965 4730.53310785381 5383.162810459632 4844.865279077923 5618.484861555164 4605.842511849263 5341.178966112039 3914.447578765234 1.6573264746915595 2.331322039278576 1.244217689219709 1.2084803826510817 1.3752037042625787 1.2376881236984603 1.4353199904972154 1.1766264381300315 1.364478348129227 1.0 11.93459300811473 -5.277422068863884 24.972118271105934 1.269977201917518 1.9943242413779145 0.7069480672139028 0.19014901197460168 331.7873343758348 518400.2269620861 0.045120108455012735 0.09441026441412588 5.279319320102752e-06 5.277422068863884 0.7243470394603966 GYTS(ph)DDDTWEPEIHLEDCK ddPTM_PC-9_Lapatinib_30min_R1 2 GYTSDDDTWEPEIHLEDCK 19 0 Q99549-2;Q99549 Q99549-2 MPHOSPH8 M-phase phosphoprotein 8 1 GY(0.002)T(0.439)S(0.555)DDDT(0.005)WEPEIHLEDCK;GYT(0.132)S(0.863)DDDT(0.005)WEPEIHLEDCK 158.0 6.9075e-06 8955500.0 45121.0 88292.0 97394.0 83951.0 97407.0 96962.0 97697.0 109449.0 97863.0 87661.0 True False 44477.56626582198 88087.56529864449 89386.64127171185 90125.0365923265 91677.71176953023 92815.16128946171 102755.27262490767 114534.4001032185 86840.63839692398 102813.08704905967 0.4326060771290572 0.8567738585323428 0.8694091757896436 0.8765910953468524 0.8916930169189848 0.9027562925444772 0.999437674465271 1.114006041357028 0.8446457633889151 1.0 16.64966439090511 -4.5515640430322 1.6446917058859647 0.9430907504954921 1.1885454505753107e-25 0.7913020234591812 0.07727648878352512 0.8927932323133618 1.4777548189181702 0.022486669457354322 1.6061737225069244 2.8082512247820933e-05 4.5515640430322 -0.9430907504954921 down GYTS(ph)DSEVYTDHGR ddPTM_PC-9_Lapatinib_30min_R1 1 GYTSDSEVYTDHGR 14 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 GYT(0.104)S(0.76)DS(0.136)EVYTDHGR 105.39 0.00055292 3413200.0 10985.0 8094.8 15661.0 9247.3 11891.0 11633.0 7407.5 15191.0 14988.0 11393.0 True False 10828.351885597725 8076.056987943033 14373.413033208235 9927.377290088489 11191.594758605486 11135.483707847487 7791.0241048241405 15896.829317472006 13299.893609363055 13362.264869781746 0.8103680020657 0.6043928231213803 1.0756719144007663 0.7429412144447813 0.8375522314270878 0.8333530143553702 0.5830616426743078 1.189680751907716 0.9953322837837363 1.0 13.705876941213877 -7.772691010712713 24.999996406211498 1.0693798911229415 0.7906128221841531 0.4588825454284312 0.13801306724094706 197.59197269965787 439022.67600134783 0.07213538505200427 0.035148417929960526 1.6877533911937546e-08 7.772691010712713 -0.27876706893878844 GYTS(ph)DSEVYTDHGRPGK ddPTM_PC-9_AZD4547_30min_R2 1 GYTSDSEVYTDHGRPGK 17 1 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 GYT(0.008)S(0.991)DSEVYTDHGRPGK 139.21 0.00037232 5423000.0 30398.0 28420.0 45284.0 56297.0 46740.0 42168.0 37727.0 47511.0 35351.0 40354.0 True False 40063.931682321345 37606.20921660921 44683.504571960046 43318.59642997955 40250.95779112735 39531.22829395699 41084.629913116776 40169.26664416755 37219.58168950312 38941.21874280163 1.028830965639134 0.9657173152435246 1.147460352155 1.1124098790048036 1.0336337456969764 1.0151512862258432 1.055042221058152 1.031535939064386 0.9557888245699355 1.0 15.249010416321612 -8.094379204605245 4.40274566353367 0.9789644205259588 1.0515006652834407 0.26162502723966596 0.048444875552823397 0.3377557335218102 10.98320894680627 0.03774610299206035 0.013469910616606502 8.046755312293468e-09 8.094379204605245 0.07253624475748188 GYTS(ph)DSEVYTDHGRPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GYTSDSEVYTDHGRPGK 17 1 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 GYT(0.44)S(0.556)DS(0.004)EVYTDHGRPGK;GY(0.001)T(0.379)S(0.61)DS(0.01)EVYTDHGRPGK;GY(0.001)T(0.211)S(0.787)DS(0.002)EVYTDHGRPGK;GYT(0.426)S(0.489)DS(0.085)EVYTDHGRPGK;GYT(0.183)S(0.807)DS(0.011)EVYTDHGRPGK 89.913 0.0011677999999999999 120446700.0 289527.0 300066.0 328516.0 385554.0 382585.0 358073.0 389397.0 361028.0 340961.0 287220.0 True False 338538.2026810898 329854.5694128912 336349.06734386756 363952.6593629334 307620.21565940237 339295.02152850927 352510.49716985645 351551.39754078555 345946.90959016053 339290.7123677309 0.9977821093852238 0.972188619933066 0.9913300160698914 1.0726867730127352 0.9066567531798414 1.0000127004973058 1.0389630022875416 1.0361362239699807 1.0196179765015656 1.0 18.372162413167082 -7.013854099669629 24.411907395296737 1.0256616897139619 0.9882403935531026 0.1564966657346052 0.03889347052848492 884.6007115530269 1558730.6392019414 0.014485858101053295 0.011704534628460194 9.686032018451607e-08 7.013854099669629 -0.03742129616085932 GYTS(ph)DSEVYTDHGRPGK ddPTM_PC-9_Lapatinib_30min_R1 6 GYTSDSEVYTDHGRPGK 17 1 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 GY(0.001)T(0.221)S(0.746)DS(0.032)EVYT(0.001)DHGRPGK;GYT(0.436)S(0.548)DS(0.016)EVYTDHGRPGK;GYT(0.415)S(0.548)DS(0.037)EVYTDHGRPGK;GYT(0.008)S(0.866)DS(0.004)EVYT(0.121)DHGRPGK;GYT(0.202)S(0.784)DS(0.014)EVYTDHGRPGK;GYT(0.425)S(0.559)DS(0.016)EVYTDHGRPGK 133.87 0.00012036 162805900.0 310637.0 263605.0 300604.0 247256.0 284594.0 273407.0 251153.5 256385.0 294276.1 191246.4 True False 306207.25941615045 262994.6388183429 275889.499484996 265440.0310618361 267854.7404533316 261714.0199528461 264156.99932648643 268297.5830794593 261131.62675328812 224303.08542019074 1.36514956467285 1.1724967506606991 1.2299853074609632 1.1833989290186662 1.1941643154464632 1.1667874272106995 1.177678848383368 1.1961386201034772 1.1641909707309905 1.0 17.775089940111968 -14.522878745280211 0.08875773095265685 0.37641452075068804 1.3648383078415516 0.6890441222620155 0.04661761847676666 131.02395884812483 0.8070008381895876 15.689227287363972 1.132646229567203 3.0000000000008723e-15 14.522878745280211 0.9884237870908635 GYTSDDDT(ph)WEPEIHLEDCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GYTSDDDTWEPEIHLEDCK 19 0 Q99549-2;Q99549 Q99549-2 MPHOSPH8 M-phase phosphoprotein 8 1 GYT(0.271)S(0.271)DDDT(0.459)WEPEIHLEDCK 121.47 7.9973e-05 2331300.0 18986.0 26531.0 24752.0 20607.0 26257.0 16146.0 21636.0 16219.0 17071.0 16370.0 True False 22199.954809407 29164.82234272937 25342.181552482733 19452.456598795416 21112.129337451606 15299.27533659145 19586.48144892492 15793.268435450998 17320.631079840925 19337.751415151306 1.1480111794183647 1.5081806419270891 1.310503016013894 1.0059316712259647 1.0917571999043312 0.7911610304703952 1.0128624072382444 0.8167065599507515 0.8956900266217122 1.0 14.239132428200314 -5.894333748473442 1.862104565749529 0.9167759878399991 1.3537800363091346 0.6790633513434559 0.11877118016370287 0.18059957991363773 1.2746839423408893 0.036528032427528744 0.06514617619444771 1.2754582624936916e-06 5.894333748473442 0.43700404846913543 GYTSDDDT(ph)WEPEIHLEDCK ddPTM_PC-9_Lapatinib_30min_R1 1 GYTSDDDTWEPEIHLEDCK 19 0 Q99549-2;Q99549 Q99549-2 MPHOSPH8 M-phase phosphoprotein 8 1 GYT(0.293)S(0.293)DDDT(0.414)WEPEIHLEDCK 122.77 6.3982e-05 1981900.0 4502.8 8645.8 8558.4 7361.9 6893.6 8279.1 7244.4 8017.3 7619.2 5976.9 True False 4438.589246287613 8625.781181296372 7854.76138837937 7903.318684578473 6488.132001339061 7925.022192524721 7619.479584878565 8389.813026592607 6761.045462267083 7009.999201281353 0.633179707848795 1.2304967423847455 1.1205081716619316 1.127435033535215 0.9255538859623693 1.130531112054351 1.0869444298204494 1.1968350902321128 0.9644859105021348 1.0 12.775198564517458 -4.750588077599078 24.999982699638803 1.0917555862239745 0.6331787340358174 0.6824173348319966 0.09282077918596623 265.5560938756433 611766.8867183744 0.0224087231803916 0.32450412164273756 1.7758730737542675e-05 4.750588077599078 -0.45857685218815714 GYVLGET(ph)SNLPSPGK ddPTM_PC-9_Lapatinib_30min_R1 1 GYVLGETSNLPSPGK 15 0 B1AKT1;Q9H040 B1AKT1 SPRTN SprT-like domain-containing protein Spartan 1 GYVLGET(0.93)S(0.04)NLPS(0.03)PGK 121.18 0.00017068 2898700.0 21503.0 25319.0 29275.0 34663.0 26930.0 27690.0 24439.0 18779.0 25794.0 21455.0 True False 21196.36327683274 25260.37541109472 26868.122504767947 37212.23265237825 25346.030346417094 26505.76324854268 25704.33183905462 19651.540896109975 22888.80809713843 25163.468163009522 0.8423466566501173 1.0038511085776185 1.067743219285817 1.4788197084486348 1.0072550485578908 1.0533430080797186 1.0214940036302378 0.7809551834749822 0.9096046677216434 1.0 14.619043155373742 -7.575221004628248 5.6159102658336595 0.8842199913088822 1.0836265461082717 0.19918089936450134 0.15895302941681333 0.3069762729237195 21.08428622374339 0.08055921653412217 0.046078627174256676 2.6593714092621247e-08 7.575221004628248 0.1994065547993895 GYVLGETSNLPS(ph)PGK ddPTM_PC-9_AZD4547_30min_R2 3 GYVLGETSNLPSPGK 15 0 B1AKT1;Q9H040 B1AKT1 SPRTN SprT-like domain-containing protein Spartan 1 GYVLGET(0.143)S(0.04)NLPS(0.817)PGK;GYVLGET(0.144)S(0.024)NLPS(0.832)PGK;GYVLGET(0.297)S(0.057)NLPS(0.646)PGK 120.21 0.0013785 0.0 59467.0 57104.0 64167.0 75950.0 73430.0 69283.0 68670.0 71061.0 59496.0 75761.0 True False 78376.26900955998 75561.75127041711 63316.10365402704 58440.90091580275 63235.51199406252 64950.72305753708 74781.4969685828 60080.15526933115 62640.83709650871 73108.63044985384 1.072052212266776 1.0335544627969184 0.8660551191347564 0.7993707522108231 0.8649527641943257 0.8884138939258016 1.0228819293759908 0.8217929251258634 0.8568186370209038 1.0 16.157754105457002 -5.197920618690468 4.757005270502919 0.8841727261462317 1.0601891239451202 0.4818858265825495 0.06754561243852426 0.17687990892189454 8.052468118497535 0.01776555346472551 0.049801130402102184 6.339855819591654e-06 5.197920618690468 0.17601639779888856 GYVLGETSNLPS(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GYVLGETSNLPSPGK 15 0 B1AKT1;Q9H040 B1AKT1 SPRTN SprT-like domain-containing protein Spartan 1 GYVLGET(0.18)S(0.098)NLPS(0.721)PGK 119.77 9.1927e-05 5147600.0 44049.0 49318.0 48043.0 52752.0 55926.0 52693.0 57458.0 55641.0 47726.0 42188.0 True False 51505.625692592905 54213.965108692755 49188.52732409214 49796.47646429154 44967.70176815015 49929.686319274944 52015.16228010391 54180.482706512674 48423.902461278696 49836.350439975766 1.0334951343322714 1.0878397922413983 0.9870009920436713 0.9991999017718552 0.9023072791477871 1.0018728473990406 1.0437193297842378 1.0871679452485008 0.9716582782200663 1.0 15.604910801945646 -10.526426755049116 14.9533832990717 0.9999537233102033 1.0132909584755279 0.005147378056307383 0.05236428654296161 0.0 0.0 0.05436730228820596 0.01318600764200929 2.975591058126177e-11 10.526426755049116 0.01333723516532459 GYVLGETSNLPS(ph)PGK ddPTM_PC-9_Lapatinib_30min_R1 1 GYVLGETSNLPSPGK 15 0 B1AKT1;Q9H040 B1AKT1 SPRTN SprT-like domain-containing protein Spartan 1 GYVLGET(0.379)S(0.076)NLPS(0.545)PGK 125.33 0.00044001 0.0 16491.0 20698.0 19709.0 24724.0 22616.0 16934.0 21499.0 13841.0 25776.0 17647.0 True False 16255.835315920984 20650.075052681317 18088.602098940115 26542.285436846196 21285.771344766763 16209.772295082032 22612.113024585095 14484.103389054708 22872.835446686822 20697.260436850553 0.7854099998170865 0.9977202111210224 0.8739611773321537 1.2824057327697744 1.028434241802765 0.7831844385656592 1.092517200214828 0.6998077563572812 1.1051141534636515 1.0 14.337152199654136 -9.886421212161132 16.010796418635923 0.9999077761224863 0.9618733968352161 0.004756996947604897 0.16897280175662086 0.0 0.0 0.15894639097135033 0.03855016228150581 1.2989091849791287e-10 9.886421212161132 -0.03803437928727016 GYY(ph)SPYSVSGSGSTAGSR ddPTM_PC-9_Lapatinib_30min_R1 2 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 GY(0.215)Y(0.744)S(0.034)PYS(0.004)VS(0.003)GSGSTAGSR;GY(0.007)Y(0.544)S(0.439)PYS(0.009)VSGSGSTAGSR 168.83 1.3515999999999997e-07 83307000.0 150463.0 128967.0 150024.0 137192.0 115573.0 111774.0 92846.0 98944.0 116708.0 86054.0 True False 148317.37002846497 128668.38483520891 137689.6058293871 147281.55733909615 108775.22336526038 106993.68657792007 97653.11158103294 103541.29945283067 103563.11605027643 100928.3192402524 1.4695317542681596 1.2748491781471496 1.364231633557943 1.4592688994305285 1.077747298122829 1.0600957925716519 0.9675491706998204 1.0258894652387727 1.0261056245646187 1.0 16.622971508099013 -6.355695697640092 4.659788065657511 1.0202521804493616 1.381055760649183 0.9106451512001565 0.05624202878346562 0.06441260813503717 2.3574016567455383 0.0180292434175126 0.02061058917684184 4.4086366057530206e-07 6.355695697640092 0.3608035801998213 GYYS(ph)PYSVSGS(ph)GSTAGSR ddPTM_PC-9_AZD4547_30min_R2 1 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 GY(0.002)Y(0.055)S(0.942)PYS(0.003)VS(0.235)GS(0.449)GS(0.271)T(0.041)AGS(0.002)R 96.15299999999999 0.010322 4137200.0 12802.0 14113.0 19062.0 25714.0 22919.0 18844.0 15317.0 25645.0 18587.0 21108.0 True False 16872.76970185795 18674.751255243 18809.22542511046 19786.034577339724 19737.09246073703 17665.681701084362 16680.18332703925 21682.154513474303 19569.470873887436 20369.015344775165 0.8283547052354676 0.9168215026178593 0.9234234010204717 0.9713790402939148 0.9689762674659563 0.8672820655327244 0.8188998360845099 1.0644674838951393 0.9607470239795945 1.0 14.314088620454882 -1.5228787462108229 0.09262777258315467 1.0522461296204353 0.5667870546001669 0.22680190569480785 0.06458180576761109 265.36279635457237 1.7676454928049388 1.1688369300814114 16.35770885381429 0.02999999993572435 1.5228787462108229 -0.4854590750202684 GYYS(ph)PYSVSGSGS(ph)TAGSR ddPTM_PC-9_AZD4547_30min_R2 1 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 GY(0.011)Y(0.305)S(0.531)PY(0.046)S(0.109)VS(0.049)GS(0.149)GS(0.688)T(0.108)AGS(0.004)R 92.671 0.013491 6146100.0 10226.0 13432.0 20418.0 22733.0 20317.0 19263.0 13822.0 23051.0 14633.0 15910.0 True False 13477.655285986519 17773.631322923822 20147.243979115807 17492.258071348835 17496.33524694769 18058.481564847603 15052.131223237999 19488.997609284303 15406.470506138428 15352.995742627114 0.877851822010621 1.1576653586619507 1.312267932386486 1.1393384304004024 1.1396039926181742 1.1762187567543443 0.9804035300710874 1.2693938001411482 1.003483018194478 1.0 13.906232567480176 GYYS(ph)PYSVSGSGS(ph)TAGSR ddPTM_PC-9_Lapatinib_30min_R1 2 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 GYY(0.001)S(0.998)PYS(0.001)VS(0.001)GS(0.028)GS(0.892)T(0.079)AGSR;GYY(0.004)S(0.996)PYSVS(0.009)GS(0.115)GS(0.614)T(0.259)AGS(0.003)R 180.76 8.7248e-08 13290600.0 95882.0 73508.0 96959.0 75467.0 62919.0 51129.0 40535.0 44527.6 60923.0 40220.0 True False 94514.70509739473 73337.7967423182 88987.40529256353 81017.09493053214 59218.22812351345 48942.33185752031 42633.70396072172 46596.51485199571 54061.210192368926 47171.97341021869 2.003619909548248 1.554690029703767 1.8864465244798623 1.7174836894354244 1.255368894757437 1.0375298788521345 0.9037930974387886 0.9878008377300932 1.146045125613885 1.0 15.525642335930707 -6.377506022220747 2.2713071162856577 1.006382583295808 1.7974124493282528 0.9049597071759347 0.11911616168493314 0.0856750238571092 0.867304525654165 0.04011336850456336 0.04743655158812232 4.192701827606324e-07 6.377506022220747 0.7910298660324449 GYYS(ph)PYSVSGSGSTAGSR ddPTM_PC-9_AZD4547_30min_R2 4 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 GYYS(0.813)PYS(0.143)VS(0.042)GS(0.001)GSTAGSR;GYYS(0.999)PYS(0.001)VSGSGSTAGSR;GYYS(0.995)PYS(0.005)VSGSGSTAGSR;GYYS(0.996)PYS(0.004)VSGSGSTAGSR 262.74 5.7995e-78 314769000.0 178065.0 185518.0 301291.0 384167.0 326970.0 244821.0 191203.0 298403.0 216852.0 216363.0 True False 234685.9660179137 245483.0654977803 297295.6844799575 295603.2334709833 281575.85941302805 229512.30416796787 208219.6965907089 252291.6729687767 228314.3540078678 208788.19722577222 1.1240384712174945 1.1757516409432294 1.4239103954639643 1.415804328974276 1.3486196210054306 1.0992589965216555 0.9972771418949099 1.2083617576139238 1.093521362996305 1.0 17.671680633254915 -6.771520410288628 22.713721701277848 1.0875558328199109 1.3044355339328555 0.5218280555117425 0.1040745062176502 61.653343201734025 138909.84036345116 0.039798801165802096 0.03558391880727669 1.6923087101058825e-07 6.771520410288628 0.21687970111294463 GYYS(ph)PYSVSGSGSTAGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 GYY(0.001)S(0.912)PYS(0.086)VSGSGSTAGSR;GYYS(0.861)PYS(0.139)VSGSGSTAGSR;GYYS(0.648)PYS(0.326)VS(0.025)GSGSTAGSR;GYYS(0.995)PYS(0.005)VSGSGSTAGSR;GY(0.003)Y(0.001)S(0.975)PYS(0.017)VS(0.005)GSGSTAGSR 257.46 2.5424999999999995e-65 221277600.0 318383.0 351367.0 370756.0 390545.0 423334.0 290705.0 277218.0 221494.0 234637.0 179989.0 True False 372278.95354911126 386248.3936563935 379596.22913995915 368664.0298139744 340384.74162854615 275459.9180430953 250957.90415548475 215680.0171922917 238068.1222354071 212619.58090786042 1.7509156586591141 1.8166172278543615 1.7853305303261733 1.7339138203538107 1.6009096630477007 1.295552915996326 1.1803141699552047 1.014393953140927 1.1196904876723226 1.0 17.69791494043959 -6.8338250430445875 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102640100.0 60894.0 67611.0 74059.0 87782.0 98262.0 74916.0 69787.0 74329.0 70900.0 57201.0 True False 71202.15148867755 74322.97325446761 75824.84743032148 82863.85913308397 79008.26647966914 70987.27307791934 63176.27014587374 72377.94250808554 71936.77837037781 67571.08849713318 1.0537369320563545 1.09992268746153 1.1221492670424937 1.226321211868588 1.169261413970284 1.0505568972879737 0.9349600776159481 1.0711377323921059 1.0646088433728553 1.0 16.044118475112718 -6.895332918336718 5.457489904575895 1.0196406183307496 1.1362524383824055 0.5090117783797365 0.054661420727646945 0.19017924913957726 8.518847315319464 0.021202940927685435 0.01867087319167965 1.2725272222760872e-07 6.895332918336718 0.11661182005165593 GYYSPYSVS(ph)GSGSTAGSR ddPTM_PC-9_Lapatinib_30min_R1 3 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 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0.017746229546146436 5.602187260232315e-08 7.251642378424563 -0.11554345061742 GYYSPYSVSGSGS(ph)TAGS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 3 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 GYYS(0.002)PYS(0.001)VS(0.001)GS(0.006)GS(0.971)T(0.018)AGS(1)R;GYYS(0.017)PY(0.001)S(0.01)VS(0.024)GS(0.134)GS(0.795)T(0.02)AGS(1)R;GYYSPYSVSGS(0.024)GS(0.975)T(0.001)AGS(1)R 171.52 6.5608e-07 73459000.0 588281.0 531278.0 519037.0 457813.0 488573.0 469314.0 395573.0 398619.0 459091.0 285507.0 True False 579892.0050624774 530047.8584326232 476363.7814007605 491482.0952393972 459836.09671147517 449242.534244368 416053.8343864458 417140.2939702049 407383.3371374494 334856.5045358353 1.7317627019558737 1.5829104444823443 1.422590796201128 1.4677394304186209 1.373233281966201 1.3415971562717293 1.2424839558161278 1.245728508539585 1.2165907832734142 1.0 18.35318346688721 -1.5228787452992705 0.1401679497133436 0.927600911181711 3.6288793754046123 0.9590110458562371 0.03951337957498986 14.092194528626136 0.13203153052840885 0.1765705571389922 7.625366528399841 0.02999999999869216 1.5228787452992705 2.7012784642229013 GYYSPYSVSGSGS(ph)TAGSR ddPTM_PC-9_AZD4547_30min_R2 4 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 GYYSPYSVS(0.036)GS(0.062)GS(0.797)T(0.077)AGS(0.028)R;GYYSPYSVS(0.004)GS(0.034)GS(0.934)T(0.019)AGS(0.008)R;GYYSPYSVSGSGS(0.373)T(0.373)AGS(0.253)R;GYYSPYSVSGS(0.002)GS(0.475)T(0.475)AGS(0.047)R 262.74 5.7995e-78 452473200.0 97266.0 91283.0 121969.0 179342.0 158634.0 135899.0 105965.0 160778.0 110753.0 120854.0 True False 128194.56474151788 120788.44461364318 120351.61136687103 137997.4727062792 136610.40732215854 127401.21404668163 115395.67971859433 135933.45441089355 116607.17747326932 116622.93824509476 1.0992225600773682 1.035717727843507 1.031972038930627 1.1832789911043375 1.1713854013441003 1.0924198615107368 0.9894766969091344 1.1655807721566387 0.9998648570164446 1.0 16.831492050606066 -8.30043455577186 22.48798829621721 0.9999319636756134 1.0937137549476186 0.28356065687879006 0.06106771649989437 269.2825367538765 155285.4668768044 0.06166649421273198 0.015925162632202013 5.0068599566975745e-09 8.30043455577186 0.09378179127200514 GYYSPYSVSGSGS(ph)TAGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 GYYSPYSVSGS(0.002)GS(0.974)T(0.021)AGS(0.002)R;GYYSPYS(0.023)VS(0.015)GS(0.391)GS(0.55)T(0.015)AGS(0.005)R;GYYSPYSVS(0.007)GS(0.022)GS(0.848)T(0.107)AGS(0.015)R 180.02 9.3446e-09 149622700.0 33668.5 31956.3 36409.2 36794.9 48261.0 39143.0 42474.0 38545.0 34731.6 32285.3 True False 39367.91206681345 35128.71027217079 37277.33341065992 34733.40104367533 38804.60349448726 37090.272172686695 38450.555234869535 37533.23459180334 35239.483944268235 38138.36931970583 1.0322389962926999 0.9210857962409009 0.9774233685287373 0.9107206643397001 1.0174688689282052 0.9725185642250941 1.0081856125663557 0.9841331777237308 0.9239903166510121 1.0 15.218955539281204 -6.284547339430675 24.990436235797823 0.984186342994237 0.9587796709371856 0.0830553893273498 0.038945889388825324 1994.1129846293493 2156556.5170506947 0.011613384112596223 0.013175170096892065 5.193410606529477e-07 6.284547339430675 -0.025406672057051383 GYYSPYSVSGSGS(ph)TAGSR ddPTM_PC-9_Lapatinib_30min_R1 4 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 GYYSPYSVS(0.028)GS(0.099)GS(0.867)T(0.004)AGS(0.002)R;GYYSPYSVSGS(0.001)GS(0.5)T(0.5)AGSR;GYYSPYSVS(0.003)GS(0.006)GS(0.588)T(0.054)AGS(0.348)R;GYYSPYSVS(0.001)GS(0.051)GS(0.497)T(0.363)AGS(0.089)R 239.33 1.2917999999999997e-43 918841200.0 146772.7 119178.0 135930.7 112287.0 113450.2 116684.6 111073.2 100608.6 125992.7 88642.0 True False 144679.69438318303 118902.05066327461 124755.00255367595 120544.96055845138 106777.28228767516 111694.2716630877 116824.02681065848 105283.24284575181 111802.07536405107 103963.6515919595 1.3916372902235814 1.143688672363548 1.199986732317937 1.1594914060115051 1.0270636001393902 1.0743588740175234 1.1237006879017089 1.0126928136284736 1.0753958104786094 1.0 16.66571968709073 -1.5228787452807682 0.4440212413727812 1.0460631221610301 7.796384441395821 0.7849722512855385 0.050994984273515606 39.29529915332826 0.47964071451223295 0.031876368385724746 239.55609071220144 0.029999999999970255 1.5228787452807682 6.750321319234791 GYYSPYSVSGSGST(ph)AGS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 GYYSPYSVSGS(0.003)GS(0.192)T(0.805)AGS(1)R 127.66 0.00032853 0.0 26418.0 23150.0 28405.0 20555.0 22237.0 21900.0 19408.0 17042.0 23259.0 15903.0 True False 26041.274475532144 23096.397597331757 26069.650546470853 22066.683269469904 20929.063379624098 20963.388051393453 20412.851275926663 17833.833534879723 20639.32649187185 18651.812360584503 1.3961793080528326 1.238292405629153 1.397700665355283 1.1830852060307981 1.122092747611591 1.123933033751392 1.0944165039459455 0.9561448072771012 1.1065587672052402 1.0 14.187028200731923 -6.208552413760084 0.7703408903006271 1.0271406579338216 1.3670938623727158 0.7910053392135458 0.06399625236874827 0.31797181347096865 0.4014159336446468 0.034658452273047514 0.06466149216517035 6.186536595051407e-07 6.208552413760084 0.3399532044388942 GYYSPYSVSGSGST(ph)AGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 GYYSPYSVSGSGS(0.118)T(0.764)AGS(0.118)R 260.44 2.5601e-65 585460000.0 37753.0 43311.0 57822.0 49384.0 74320.0 51877.0 64644.0 44330.0 49044.0 50474.0 True False 44143.83724426116 47610.62984757274 59200.69577115611 46617.17458508822 59757.52951058398 49156.478795760886 58520.452337969225 43166.38447151752 49761.17571786765 59624.53664803585 0.7403636107873275 0.7985073348010853 0.9928915023796047 0.7818454818403001 1.0022305055942522 0.8244337240879875 0.9814827188245664 0.7239701454843843 0.8345754703572507 1.0 15.86361852929354 -5.014626250375292 20.095702409692638 0.8843217334525925 0.7548986077050799 0.21702320848559853 0.09539294319988344 68.2292532345645 93760.0332120912 0.022951515078284197 0.06691640422529282 9.668826108583182e-06 5.014626250375292 -0.12942312574751258 GYYSPYSVSGSGST(ph)AGSR ddPTM_PC-9_Lapatinib_30min_R1 1 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 GYYSPYSVSGSGS(0.045)T(0.478)AGS(0.478)R 263.07 1.3701999999999998e-77 255870000.0 20448.0 15930.0 21730.0 13728.0 15926.0 17099.0 11971.0 14176.0 17796.0 11164.0 True False 20156.407770296064 15893.115063736286 19943.443280225725 14737.602915265517 14989.263991720714 16367.71562971581 12590.799805447143 14834.668712032326 15791.627079812179 13093.682524905062 1.539399457101333 1.2138002455387562 1.5231347821586447 1.125550652937675 1.1447706909962212 1.250046776266594 0.9615934846059233 1.132963830749355 1.206049333315929 1.0 13.67658328380406 -1.5228787452807797 0.26049107503388397 1.0405007476915473 4.104776494095808 0.5460075063207148 0.12264404053895528 39.50300861774335 0.5454507750162437 0.14643641291577641 53.767447508668546 0.029999999999969457 1.5228787452807797 3.0642757464042605 GYYSPYSVSGSGSTAGS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 GYYSPYSVSGSGST(0.008)AGS(0.992)R 276.3 1.3084e-91 879120000.0 50067.0 49488.0 76744.0 99595.0 89981.0 86215.0 53996.0 102890.0 70025.0 68359.0 True False 65987.26454170608 65484.02820941444 75726.32441636118 76634.91147741106 77488.69133511839 80823.96242087592 58801.53939588766 86990.71467698833 73726.37854112923 65965.77221686012 1.0003258102516455 0.99269706104763 1.1479638890213184 1.1617375026775483 1.1746802732844102 1.2252409045583523 0.8913946948514405 1.3187250259272256 1.1176459558262488 1.0 16.0094300242964 -5.260044170098669 23.794541404158974 1.1387122585102714 0.9965114099558176 0.1842953015423402 0.11076155189606744 91.75210672243202 1564695.8807069438 0.027382550845342975 0.06483466365283709 5.494849854194506e-06 5.260044170098669 -0.1422008485544538 GYYSPYSVSGSGSTAGS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 GYYSPYSVSGS(0.028)GS(0.291)T(0.042)AGS(0.639)R;GYYSPYSVSGSGSTAGS(1)R;GYYSPYSVSGSGSTAGS(1)R;GYYSPYSVSGSGST(0.001)AGS(0.998)R 256.89 2.8291999999999997e-65 1199500000.0 86349.0 89212.0 96414.0 106972.0 135611.0 103591.0 107200.0 100365.0 90218.0 86317.0 True False 100966.1802295106 98068.37777843192 98712.87541213105 100978.70564790326 109038.99804170875 98158.50559846683 97045.23993921027 97730.5250955075 91537.26757431243 101965.58881500419 0.9901985699576863 0.9617791543023112 0.9680998909467926 0.9903214096189703 1.0693705524472361 0.9626630585790611 0.9517450060066746 0.9584657552737684 0.8977270531962325 1.0 16.63772283033913 -10.178779783767041 5.462199255850972 1.000000000956412 0.9739281228866582 0.03890356094203973 0.04060661346323303 58590208.823593624 18.297017373278052 0.8587363154465859 0.010401476238277635 6.625523767306578e-11 10.178779783767041 -0.026071878069753862 GYYSPYSVSGSGSTAGS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 GYYSPYSVSGSGST(0.009)AGS(0.99)R 132.64 4.0028000000000004e-05 251250000.0 15717.0 9799.9 13000.0 11582.0 13314.0 12513.0 11774.0 10993.0 13840.0 10368.0 True False 15492.872697855204 9777.208933654065 11931.19018145119 12433.778916419376 12530.896696331123 11977.84815922767 12383.60010937554 11503.774911919538 12281.193458338987 12160.09498550839 1.274074973618101 0.8040405066988296 0.9811757388137186 1.0225067264060967 1.0304933235525404 0.985012713593281 1.0183802120076784 0.9460267313395979 1.009958678199053 1.0 13.569866877622617 -4.737270615700987 24.974749063471982 0.9805118675418262 1.2740762839875683 0.6680321375979361 0.0626855008610844 1354.675874864666 1399778.745737771 0.015552019589454534 0.9999257547013747 1.831173034171106e-05 4.737270615700987 0.29356441644574216 HAAFVT(ph)PDQK ddPTM_PC-9_Lapatinib_30min_R1 1 HAAFVTPDQK 10 0 P10244-2;P10244 P10244-2 MYBL2 Myb-related protein B 1 HAAFVT(1)PDQK 84.71799999999999 0.025931 2545700.0 66764.0 54158.0 46714.0 53940.0 52830.0 57534.0 32869.0 33580.0 47010.0 36272.0 True False 65811.93311698202 54032.60047845761 42873.35524125464 57906.92753856513 49722.6432677763 55073.40493830457 34570.795990747836 35140.24938981701 41715.238762753994 42541.56687059805 1.5470030362813676 1.2701130788814787 1.0077991572728342 1.3611846435911745 1.1688014082561058 1.2945786671615922 0.8126357004175347 0.826021512012141 0.9805759832411072 1.0 15.37658555047878 -7.257224593813313 24.95368188418094 0.8903100850362569 1.2616517499519342 0.6252557421853215 0.13996300139753812 237.40279753158913 1405550.9681169111 0.055335607706436224 0.04130638657574909 5.530640201986698e-08 7.257224593813313 0.3713416649156773 HAALCAMEVLPLALPS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HAALCAMEVLPLALPSPPR 19 0 H7BYF1;Q9ULI0-2;Q9ULI0 H7BYF1 ATAD2B ATPase family AAA domain-containing protein 2B 1 HAALCAMEVLPLALPS(1)PPR;HAALCAMEVLPLALPS(1)PPR 74.308 0.0030444 6425000.0 45882.0 44831.0 52416.0 62207.0 64164.0 55046.0 60475.0 57599.0 46114.0 41867.0 True False 53648.91638919265 49281.52540224269 53665.79622878697 58721.74346781513 51591.52480512796 52159.290857055224 54746.37019891542 56087.087281185144 46788.33001088306 49457.155681010336 1.0847553938446928 0.9964488398827375 1.085096696116566 1.1873255277064396 1.043155921417801 1.0546358790520258 1.1069453842436787 1.1340540415008227 0.9460376232037945 1.0 15.593891651163752 -8.268370643546945 24.988340648798562 0.9730188002787981 1.0850287103283272 0.44859042260559767 0.05032689520466504 569.7022154389415 2053840.6780491525 0.04663872840123905 0.013107170264464363 5.39050379905646e-09 8.268370643546945 0.1120099100495291 HAAS(ph)YSSDSENQGSYSGVIPPPPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HAASYSSDSENQGSYSGVIPPPPGR 25 0 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;F2Z3L2;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 HAAS(0.314)Y(0.02)S(0.314)S(0.314)DS(0.033)ENQGS(0.004)Y(0.001)SGVIPPPPGR 75.17399999999999 9.695e-05 8547400.0 5159.9 4606.3 6814.6 11426.0 10361.0 10105.0 9137.8 10042.0 8433.6 4110.5 True False 6033.369157329569 5063.583022023833 6977.08590851442 10785.838263591806 8330.836427060833 9575.076011164167 8272.201432057038 9778.408140378499 8556.925445196326 4855.701111299903 1.2425330593946704 1.0428119247785166 1.4368853742413747 2.2212731007045794 1.7156814713479376 1.971924505172201 1.7036059762423301 2.0137994320990558 1.762243031244891 1.0 12.245463905078504 -5.53895904387088 8.82234638120249 1.8169717827167455 1.1660985924032041 0.40057632523166475 0.3067334763985671 0.14800415613422527 68.64967811061587 0.07611573885198597 0.13483247922595187 2.8909525007063704e-06 5.53895904387088 -0.6508731903135414 HAASYS(ph)SDSENQGSYSGVIPPPPGR ddPTM_PC-9_AZD4547_30min_R2 1 HAASYSSDSENQGSYSGVIPPPPGR 25 0 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;F2Z3L2;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 HAAS(0.016)YS(0.54)S(0.423)DS(0.021)ENQGSYSGVIPPPPGR 167.28 1.296e-10 13655000.0 10110.0 5008.5 21858.0 22611.0 20021.0 20362.0 16147.0 19730.0 16488.0 14717.0 True False 13324.769698936398 6627.399678444314 21568.148638236515 17398.383286467637 17241.429737615766 19088.7609211144 17584.051719116196 16681.181850296263 17359.522019080858 14201.762309506168 0.9382476208616207 0.4666603717207802 1.5186952272676428 1.2250862186886315 1.2140345234531176 1.3441121253196193 1.2381598379058942 1.174585342773302 1.2223498493184184 1.0 13.793782345718105 -5.259366128971238 24.99999974682413 1.2502516944288071 0.7024539898649189 0.6387142115415696 0.16226218173909782 98.3562776658739 1185995.2650503162 0.03888346563393473 0.09295518547279331 5.5034353745180025e-06 5.259366128971238 -0.5477977045638882 HAASYS(ph)SDSENQGSYSGVIPPPPGR ddPTM_PC-9_Lapatinib_30min_R1 2 HAASYSSDSENQGSYSGVIPPPPGR 25 0 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;F2Z3L2;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 HAAS(0.033)Y(0.007)S(0.454)S(0.454)DS(0.052)ENQGSYSGVIPPPPGR;HAAS(0.018)YS(0.523)S(0.437)DS(0.022)ENQGSYSGVIPPPPGR 143.04 2.9559e-09 26915000.0 30248.0 24209.5 38138.0 26717.0 32547.0 29193.0 26909.0 27889.0 35027.0 30688.0 True False 29816.65797319617 24153.444390177236 35002.44085693734 28681.857305299323 30632.649449863995 27944.48344220681 28302.21635325179 29184.824753800047 31081.890409338135 35992.37991081034 0.8284158493292829 0.6710710558743221 0.9724958711725625 0.7968869348560278 0.8510870780362999 0.7763999910940499 0.7863391202078082 0.8108612107929646 0.8635686355378424 1.0 15.135403879756124 -8.68836606131958 2.3524289179263294 0.9998752304709042 0.811211685540228 0.39452879565344945 0.07044166996158328 0.6537646298281092 6.811349561997703 0.06559949788794642 0.01783633373107324 2.0494340086263982e-09 8.68836606131958 -0.18866354493067616 HAASYSS(ph)DSENQGSYSGVIPPPPGR ddPTM_PC-9_AZD4547_30min_R2 1 HAASYSSDSENQGSYSGVIPPPPGR 25 0 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;F2Z3L2;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 HAAS(0.011)YS(0.293)S(0.53)DS(0.165)ENQGSYSGVIPPPPGR 118.11 3.5988000000000004e-09 12483000.0 5342.4 6086.3 15371.0 25932.0 21323.0 17828.0 16926.0 15576.0 13653.0 16910.0 True False 7041.172071176837 8053.577450916565 15167.17049676701 19953.778045406165 18362.6695117717 16713.212341696675 18432.38120999322 13169.087100872517 14374.669706848066 16317.986047003416 0.4314976156306896 0.49353991526396107 0.9294756382974272 1.2228088679528204 1.125302439827969 1.0242202863487457 1.1295745171554479 0.8070289472573025 0.8809095476269135 1.0 13.99417539155911 -5.287007240404201 3.6535382790926425 1.0300980177343904 0.4441613635966811 0.7917173488480548 0.11432169887412967 0.10079922057210491 2.9118167810414493 0.03358591977582909 0.08641952445799317 5.164077598325383e-06 5.287007240404201 -0.5859366541377092 down HAASYSS(ph)DSENQGSYSGVIPPPPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HAASYSSDSENQGSYSGVIPPPPGR 25 0 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;F2Z3L2;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 HAAS(0.008)Y(0.001)S(0.175)S(0.776)DS(0.041)ENQGSYSGVIPPPPGR 125.42 5.0317e-09 9256400.0 7435.8 12267.0 14658.0 19318.0 17982.0 17098.0 12072.0 16697.0 8461.3 8728.2 True False 8694.534076255586 13484.786690221306 15007.502310774564 18235.67508980102 14458.556184867088 16201.350780691248 10928.45276628866 16258.721441933849 8585.03050529307 10310.553567606818 0.8432654967791098 1.3078625315120942 1.4555476786352564 1.7686417097034397 1.402306490147363 1.5713366575769359 1.0599288093146741 1.576900923439716 0.8326449641137689 1.0 13.331834171790078 -8.269757174261272 24.81658408930386 0.9163224099796363 1.3840998268638174 0.34125404054998265 0.25356326808262375 702.133342270046 2094823.2245684394 0.23252827285721228 0.06412612227746359 5.373321492676947e-09 8.269757174261272 0.46777741688418106 HACQLSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HACQLSQR 8 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996;Q6XYB5;J3KNK7;Q86XE2;Q6P996-2 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 0 91.318 0.0073982 379520.0 2501.2 3308.6 3063.9 2865.3 3881.8 2853.8 3068.8 3404.6 2830.7 2485.4 False True 2924.6037590481815 3637.055942224356 3136.954995905457 2704.7665304279353 3121.1891557344575 2704.1417041722234 2778.101047812017 3315.23285747188 2872.093632341732 2935.9833455844255 0.996124097041164 1.2387862988713165 1.068451222866534 0.9212472320375288 1.0630813558355405 0.9210344153481387 0.9462250703806424 1.12917290980476 0.9782390750483034 1.0 11.519628069154212 -5.526488248082626 24.723458788229905 0.9971619999829119 1.1264960911376212 0.278263273948297 0.08117718438819385 99.53245998227307 681750.6284922198 0.0211944298663509 0.03694476250931416 2.9751697652599737e-06 5.526488248082626 0.12933409115470929 HADAEMT(ph)GYVVTR ddPTM_PC-9_AZD4547_30min_R2 1 HADAEMTGYVVTR 13 0 O15264;Q5R3E6;O15264-2 O15264 MAPK13 Mitogen-activated protein kinase 13 1 HADAEMT(0.738)GY(0.262)VVTR 95.618 0.013257 7670600.0 7336.8 5917.6 10005.0 16631.0 10618.0 12597.0 10691.0 24294.0 16828.0 15712.0 True False 9669.749785079786 7830.348475024874 9872.327162849126 12796.979896388617 9143.873980021195 11809.307598628731 11642.478288788703 20539.92052058274 17717.49372495711 15161.927662360591 0.6377651971711282 0.5164480829481646 0.6511261221326843 0.8440206404728506 0.603081229751598 0.7788790358065932 0.7678758630204454 1.3547037670924251 1.1685515271874498 1.0 13.888165566576458 -7.654404489774379 5.3592067734380215 1.1933222653571827 0.6770845548905289 0.7855941995531672 0.11752520798576238 0.08957188908861667 3.8691120808807944 0.05847982361932291 0.032822742499709304 2.2161314152806878e-08 7.654404489774379 -0.5162377104666538 HADAEMTGY(ph)VVTR ddPTM_PC-9_AZD4547_30min_R2 1 HADAEMTGYVVTR 13 0 O15264;Q5R3E6;O15264-2 O15264 MAPK13 Mitogen-activated protein kinase 13 1 HADAEMT(0.226)GY(0.723)VVT(0.051)R 80.014 0.013868 6641500.0 6447.0 5303.3 10179.0 13941.0 9920.6 9223.7 8996.9 15917.0 16890.0 11332.0 True False 8497.011894069537 7017.488013316104 10044.019809159556 10727.117836302916 8543.295932020928 8646.940580890037 9797.606670695268 13457.393386272968 17782.77091838159 10935.270129192351 0.7770280746322179 0.6417297360201926 0.9184976402500062 0.9809650524925068 0.7812606210078061 0.7907386355099283 0.895963844966205 1.2306411480725712 1.62618487776625 1.0 13.416701238639863 -7.780499779648975 3.463291228003685 1.3450936739521313 0.8201850862288315 0.6220278884284072 0.16497791255922176 0.14014995193699337 3.4943780585916135 0.09377793452561446 0.0440007580051293 1.657678177916422e-08 7.780499779648975 -0.5249085877232998 HADAEMTGY(ph)VVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HADAEMTGYVVTR 13 0 O15264;Q5R3E6;O15264-2 O15264 MAPK13 Mitogen-activated protein kinase 13 1 HADAEMT(0.04)GY(0.959)VVT(0.001)R;HADAEMT(0.18)GY(0.78)VVT(0.04)R;HADAEMT(0.21)GY(0.788)VVT(0.001)R 101.39 0.0021106 24502400.0 47535.4 40243.2 61565.2 49442.0 80070.0 64984.0 81027.0 82677.0 77593.0 71800.2 True False 55582.204353054105 44238.278937956624 63033.14785532116 46671.925033126725 64380.85828730444 61576.12464220608 73351.5359753207 80506.81635352255 78727.65083346584 84817.0078899297 0.6553190891287426 0.5215732084697723 0.7431663698526327 0.550266110468017 0.7590559946520864 0.7259879377272516 0.8648210753969513 0.9491824618241586 0.9282059435017297 1.0 16.37206596908012 -7.187679929339715 0.8014815870712209 0.9904830090291886 0.6089141342125608 0.8299700042862308 0.0645363615848318 0.2339587390883465 0.29926395994840554 0.04775808439974434 0.030691921380988304 6.491126467922414e-08 7.187679929339715 -0.3815688748166278 HADAEMTGY(ph)VVTR ddPTM_PC-9_Lapatinib_30min_R1 3 HADAEMTGYVVTR 13 0 O15264;Q5R3E6;O15264-2 O15264 MAPK13 Mitogen-activated protein kinase 13 1 HADAEMT(0.227)GY(0.772)VVT(0.001)R;HADAEMT(0.025)GY(0.724)VVT(0.251)R;HADAEMT(0.015)GY(0.976)VVT(0.009)R 78.548 0.024502 4816300.0 26570.2 20747.9 28062.1 21166.3 34058.9 28019.5 35317.7 27088.3 39729.7 32403.2 True False 26191.304075622073 20699.85951229718 25754.942460838574 22722.940310706927 32055.622464373744 26821.17130164467 37146.27769516672 28346.921308701014 35254.92281371174 38004.049945449995 0.6891713939229207 0.5446750949440706 0.6776894172543857 0.5979083898511561 0.8434791163148542 0.7057450808569894 0.9774294515580708 0.7458921180608233 0.9276622587412584 1.0 15.213865548760442 -6.88211203678483 0.41197737858675976 0.9809555852933463 0.5612510137677729 0.6557635806531084 0.08826633815288891 0.8020347793904588 0.2910598636352643 0.08702686804440261 0.12948049403131764 1.3118614289199984e-07 6.88211203678483 -0.4197045715255734 HADDDRPPR ddPTM_PC-9_Lapatinib_30min_R1 2 HADDDRPPR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 ; 110.41 0.0029864 1565480.0 7163.200000000001 9419.6 8086.900000000001 7710.5 11675.400000000001 8062.0 9600.6 12787.400000000001 11896.3 7992.6 False True 7061.051454430003 9397.789494938494 7422.026298336743 8277.555891473978 10988.67592671958 7717.207053439905 10097.67209190342 13381.549286698797 10556.413420407376 9374.110260529938 0.7532503094358554 1.0025260247373298 0.791757947374214 0.8830230988776561 1.1722366839429907 0.8232468830597727 1.077187254178145 1.4275007349809334 1.1261243069494895 1.0 13.194466048903413 -7.520546251549302 24.945749094573547 1.2165563445178973 0.9178375166038425 0.4137807120543564 0.1498691621271083 81.69578326553581 873759.4449185185 0.06680880606938076 0.03941047836673357 3.01615564112783e-08 7.520546251549302 -0.2987188279140548 HAEATLGS(ph)GNLR ddPTM_PC-9_AZD4547_30min_R2 1 HAEATLGSGNLR 12 0 D6RCK3;Q9H8S9-2;Q9H8S9;Q7L9L4;Q7L9L4-2 D6RCK3 MOB1B;MOB1A MOB kinase activator 1A;MOB kinase activator 1B 1 HAEAT(0.017)LGS(0.983)GNLR 99.238 0.0019316 5904200.0 21736.0 26502.0 35785.0 45222.0 38708.0 31305.0 27283.0 36063.0 39654.0 39573.0 True False 28647.5958631139 35068.25322514348 35310.46751849637 34796.766572935274 33334.06234871543 29347.493401212392 29711.13414582567 30490.291995298256 41750.02948475451 38187.56131508374 0.7501813385448722 0.9183161222524006 0.9246588758876587 0.9112068268991785 0.8729036681257983 0.7685092315549461 0.778031723489241 0.7984351696020681 1.093288705719567 1.0 15.220815170916724 -8.261370390004751 24.999999826187498 1.0466443684005629 0.8446785084381478 0.6141849482320407 0.06534917792945116 4.44280847247973 1611654.7666168471 0.05595214545803028 0.018025756163932493 5.478095637830501e-09 8.261370390004751 -0.201965859962415 HAEATLGS(ph)GNLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HAEATLGSGNLR 12 0 D6RCK3;Q9H8S9-2;Q9H8S9;Q7L9L4;Q7L9L4-2 D6RCK3 MOB1B;MOB1A MOB kinase activator 1A;MOB kinase activator 1B 1 HAEAT(0.038)LGS(0.962)GNLR 67.32600000000001 0.021055 4873100.0 30076.0 25170.0 40119.0 41633.0 45469.0 46481.0 43427.0 41570.0 40539.0 31185.0 True False 35167.27277192275 27668.711257265026 41075.58911215478 39300.43798600716 36559.67585194756 44043.45453487599 39313.280175746986 40478.8315470558 41131.80618274685 36838.59363967582 0.954631252102061 0.7510794664936756 1.1150151255479972 1.0668278591308624 0.9924286526663749 1.1955791517361405 1.0671764660800158 1.098815876170131 1.1165411629190742 1.0 15.168930365305686 -5.272534636300985 24.99909423082553 1.0849278956382793 0.8528553573348397 0.6189100854998659 0.07174223178240718 371.6927921596349 837474.2144054691 0.017714121425127096 0.03742592369928266 5.339066911996293e-06 5.272534636300985 -0.23207253830343955 HAEATLGS(ph)GNLR ddPTM_PC-9_Lapatinib_30min_R1 2 HAEATLGSGNLR 12 0 D6RCK3;Q9H8S9-2;Q9H8S9;Q7L9L4;Q7L9L4-2 D6RCK3 MOB1B;MOB1A MOB kinase activator 1A;MOB kinase activator 1B 1 HAEAT(0.015)LGS(0.985)GNLR;HAEAT(0.009)LGS(0.991)GNLR 95.755 0.0025486000000000003 10499200.0 65611.0 59221.0 68405.0 62193.0 63779.0 64704.0 62838.0 55807.0 68370.0 58805.0 True False 64675.37510841619 59083.87741302736 62781.00495093603 66766.88068976605 60027.64461433853 61936.76075239093 66091.4441713046 58399.99695346983 60669.45063198242 68969.36589726285 0.9377406079788669 0.8566684156707927 0.9102737734961195 0.968065746598604 0.8703522764549706 0.8980329157245301 0.9582724636000682 0.84675270235865 0.8796579444032583 1.0 16.073668082283206 -11.911046628442753 2.3049728313492897 1.7650432569476175 0.902525554497593 0.353970147293881 0.039363803067467035 9156878.071053091 468896.8695812632 37038321.6481892 0.010204091470536561 1.227307453044827e-12 11.911046628442753 -0.8625177024500246 HAEELER ddPTM_PC-9_AZD4547_30min_R2 1 HAEELER 7 0 Q9UHB9-4;Q9UHB9-2;Q9UHB9 Q9UHB9-4 SRP68 Signal recognition particle subunit SRP68 0 126.28 0.0038263000000000004 3140200.0 9142.3 1452.1 2951.8 8698.4 6039.1 10436.0 6695.9 6496.0 7626.6 7449.0 False True 12049.361228346812 1921.4629276368153 2912.6572033281436 6693.118268940337 5200.675207453942 9783.435270246044 7291.822128322912 5492.192463229832 8029.7265059875135 7188.212777299137 1.6762666328408518 0.2673074639227327 0.4051990798778957 0.9311241161471538 0.7235004539484455 1.361038629955807 1.0144137846546475 0.7640553547015954 1.1170685613739668 1.0 12.811417399159762 -6.656382565529964 21.175148304336457 1.0353246812131094 0.7562886423240492 0.09266628448118897 0.37794704201690554 8.503364908512326 1682.6014985917934 0.12384285562031075 0.12384266594109715 2.2060605808396048e-07 6.656382565529964 -0.27903603888906015 HAELSGS(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 1 HAELSGSPLK 10 0 F6RRE2;E7EV10;Q9BTC8 F6RRE2 MTA3 Metastasis-associated protein MTA3 1 HAELS(0.036)GS(0.964)PLK 93.766 0.0037314 8470400.0 67114.0 47631.0 74388.0 92709.0 79068.0 75059.0 75288.0 68123.0 71510.0 79735.0 True False 88454.85594207898 63026.78927502861 73401.56651574426 71336.3723897717 68090.77301302648 70365.54886444972 81988.48614781798 57596.155660807555 75289.87260944159 76943.50191944523 1.1496078776695837 0.8191307609187518 0.9539670626454051 0.9271266658028663 0.8849450741703052 0.9145093101964323 1.0655673851919882 0.7485512645513188 0.9785085254927065 1.0 16.231511871867177 -4.7455966839433685 24.948051752667542 0.9178620347225884 1.1496085391157778 0.39006262827118043 0.08552175637564419 886.1677889227251 1395401.6834065218 0.019926251134360466 0.4996632086871782 1.7964011154368542e-05 4.7455966839433685 0.23174650439318933 HAELSGS(ph)PLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HAELSGSPLK 10 0 F6RRE2;E7EV10;Q9BTC8 F6RRE2 MTA3 Metastasis-associated protein MTA3 1 HAELS(0.007)GS(0.993)PLK;HAELS(0.006)GS(0.994)PLK 110.31 0.00099664 13454300.0 66813.0 65209.0 56943.0 68854.0 82782.0 65073.0 72844.0 68624.0 61596.0 57844.0 True False 78123.12128309863 71682.51856873241 58300.737077530095 64996.333607679946 66561.46135555932 61660.4573255305 65943.6889751103 66822.69271313837 62496.72497181664 68330.65930714791 1.1433099296164166 1.0490535185167438 0.8532149062907021 0.9512030802384023 0.974108285072503 0.9023834681349304 0.9650673598609941 0.9779313325921356 0.9146220101710478 1.0 16.060245426668804 -5.015136050941572 4.742530161047098 0.9422714636542073 1.127673808566793 0.7119227448570185 0.041165786576297485 0.08541977583727917 5.26959104346575 0.01021961501146974 0.03580532345225266 9.657482927205408e-06 5.015136050941572 0.18540234491258567 HAELSGS(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 1 HAELSGSPLK 10 0 F6RRE2;E7EV10;Q9BTC8 F6RRE2 MTA3 Metastasis-associated protein MTA3 1 HAELS(0.018)GS(0.982)PLK 69.352 0.03558 0.0 73730.0 68430.0 61396.0 52137.0 54496.0 46118.0 49332.0 55956.0 57976.0 48924.0 True False 72678.59667957398 68271.55453932675 56348.25787541364 55971.32890393346 51290.65242325831 44145.64064630883 51886.16957667019 58555.920037421034 51446.13236565468 57380.448212867705 1.2666090792799982 1.189805180434556 0.982011462621817 0.9754425182649891 0.8938698462755517 0.7693498747611571 0.9042482447014868 1.0204855810849125 0.8965794790379097 1.0 15.808271616947696 -5.216788557088298 1.541786540481512 0.9117547768710431 1.297743326683907 0.7733121950212095 0.06592942039609244 0.2615847760378983 0.9824460581830636 0.020914939686672625 0.11879739393238926 6.07031800372909e-06 5.216788557088298 0.3859885498128638 HAEQQALR ddPTM_PC-9_AZD4547_30min_R2 1 HAEQQALR 8 0 K7EK20;K7EPK1;K7EQA8;Q86X55-2;Q86X55-1;Q86X55 K7EK20 CARM1 Histone-arginine methyltransferase CARM1 0 123.98 0.0027771999999999996 798310.0 4599.2 3133.5 3184.3 7023.6 5511.4 4832.9 5793.4 5586.4 4859.2 6099.8 False True 6061.649930697158 4146.342596067733 3142.0741014153427 5404.417533538282 4746.237243688904 4530.697999000775 6309.001376697078 4723.150242701219 5116.047391746588 5886.247858634622 1.029798621511535 0.704411824926027 0.5337991496240153 0.9181430451676383 0.8063264336935081 0.7697090078112542 1.0718205431057939 0.8024042405507545 0.8691525594257441 1.0 12.523132577347175 -7.1520641551540125 23.202586564898827 0.9196308051760261 0.7840537195752866 0.19466514613344743 0.1392676301841924 27.348202971978203 5771.4544225595755 0.053995269513068544 0.04182454812082793 7.045889774919606e-08 7.1520641551540125 -0.13557708560073956 HAESVGDGER ddPTM_PC-9_AZD4547_30min_R2 2 HAESVGDGER 10 0 P30533 P30533 LRPAP1 Alpha-2-macroglobulin receptor-associated protein 0 ; 120.63 0.00057903 13215600.0 50808.0 39750.0 70746.0 97529.0 81625.0 70421.0 56251.0 69686.0 70485.0 79065.0 False True 66963.88712794876 52598.4101463834 69807.8618153848 75045.19585802934 70292.77770005926 66017.5637376387 61257.23002737381 58917.629924974404 74210.69320202045 76296.95841551287 0.8776743990666542 0.6893906551285139 0.914949471972546 0.9835935457522903 0.9213051104507356 0.8652712389674483 0.8028790570361564 0.772214661613498 0.9726559845003175 1.0 16.219337924599813 -8.419187696394133 6.448893153788092 0.9992220055247129 0.855546268440732 0.3146126081266627 0.07887233024548176 0.29545491735033 14.501028968803915 0.08234947754771535 0.021330003206238717 3.8090116731323655e-09 8.419187696394133 -0.14367573708398085 HAESVGDGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HAESVGDGER 10 0 P30533 P30533 LRPAP1 Alpha-2-macroglobulin receptor-associated protein 0 ; 119.53 0.00065637 9625900.0 26302.0 30058.0 43274.0 35045.0 49229.0 46689.0 38073.0 32069.0 44476.0 31161.0 False True 30754.40911182044 33041.95959359841 44305.81627755888 33081.542267422985 39582.93084333339 44240.54664871291 34466.44981535026 31227.222729914145 45126.377359674625 36810.24262965973 0.835485096396517 0.897629497475112 1.2036273904334336 0.8987048143162099 1.0753238233599574 1.2018542527363358 0.9363276999315139 0.8483297174670865 1.2259190414385965 1.0 15.167819638629023 -5.0218594156623295 22.330281667261502 1.0410686279350743 0.8510209060895395 0.25596520865635464 0.1256721372658603 227.28650404330153 232188.94947526447 0.03138658863138055 0.08522507277984075 9.509125612733207e-06 5.0218594156623295 -0.19004772184553476 HAESVGDGER ddPTM_PC-9_Lapatinib_30min_R1 2 HAESVGDGER 10 0 P30533 P30533 LRPAP1 Alpha-2-macroglobulin receptor-associated protein 0 ; 136.96 9.7646e-05 23400400.0 52207.0 52416.0 61912.0 47751.0 55751.0 55825.0 50863.0 54541.0 68578.0 42649.0 False True 51462.51860640874 52294.63397242944 56821.83434723121 51262.76783266635 52471.8357906832 53437.494884431 53496.43726542966 57075.17397170959 60854.023481645316 50020.822823779665 1.0288219125804483 1.0454572919893836 1.135963607544224 1.0248285601630742 1.0489998530319724 1.0683049951554788 1.0694833520410965 1.1410282908136473 1.2165738195877018 1.0 15.610241169055994 -7.719241738761254 5.720930983602848 1.1342268658281158 1.0606474026599793 0.16660033285865627 0.05768769896865417 0.2540321449535046 20.078521280158395 0.027319391149126473 0.01504151374116133 1.9087904840864193e-08 7.719241738761254 -0.07357946316813657 HALTS(ph)PSLGGQGR ddPTM_PC-9_AZD4547_30min_R2 1 HALTSPSLGGQGR 13 0 M0QZ22;Q5PRF9;M0QX45 M0QZ22 SAMD4B Protein Smaug homolog 2 1 HALT(0.167)S(0.829)PS(0.003)LGGQGR 64.374 0.023916999999999997 5159200.0 17963.0 18982.0 29761.0 41098.0 31329.0 32625.0 25575.0 31846.0 21952.0 24653.0 True False 23674.86034638917 25117.560286758486 29366.349694508055 31623.49105777041 26979.509127903937 30584.953592542868 27851.125454660076 26924.93244827852 23112.337904103788 23789.905973789184 0.9951640991130117 1.0558074636542094 1.2344037730482325 1.329281885040318 1.1340738024618062 1.2856273423795879 1.1707118760933897 1.1317796916870284 0.9715186739101905 1.0 14.53806194927735 -8.15133929016727 3.2841450231219182 0.983713499359728 1.178057251453186 0.3756250289891204 0.09422807287593003 0.2856174197692841 5.464507607612727 0.08302795877463354 0.026755407590675524 7.0576596306345505e-09 8.15133929016727 0.194343752093458 HALTS(ph)PSLGGQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HALTSPSLGGQGR 13 0 M0QZ22;Q5PRF9;M0QX45 M0QZ22 SAMD4B Protein Smaug homolog 2 1 HALT(0.014)S(0.985)PSLGGQGR 74.85300000000001 0.010777 3385300.0 17387.0 26453.0 23412.0 28056.0 30580.0 32036.0 31761.0 25288.0 24706.0 22428.0 True False 20330.275691096587 29079.079018213433 23970.23087050444 26484.113278779234 24588.068520366767 30355.975763845145 28752.3681502729 24624.21679485076 25067.278510840013 26494.01886004969 0.7673534090274463 1.0975714621409043 0.9047412171450188 0.9996261200943963 0.9280611088204174 1.1457671229191617 1.0852399668828112 0.9294255025983089 0.9461485870925737 1.0 14.693379081305112 HALTS(ph)PSLGGQGR ddPTM_PC-9_Lapatinib_30min_R1 1 HALTSPSLGGQGR 13 0 M0QZ22;Q5PRF9;M0QX45 M0QZ22 SAMD4B Protein Smaug homolog 2 1 HALT(0.088)S(0.899)PS(0.013)LGGQGR 76.156 0.0099492 4381600.0 30330.0 14228.0 31565.0 23400.0 25506.0 28683.0 22275.0 31144.0 42176.0 25277.0 True False 29897.48863815919 14195.055940165706 28969.847544423592 25120.9140601117 24005.787226725388 27456.294953338715 23428.290507587924 32591.06393676176 37425.6947470307 29646.095770514625 1.0084797967864152 0.4788170439051137 0.977189299011723 0.8473599442762519 0.8097453173109234 0.9261352714324751 0.7902656285314036 1.0993374705743255 1.2624156326261853 1.0 14.855554501744237 -7.815130468268082 5.5054990965788635 1.1437458601443655 0.8288628410310692 0.4338020277548743 0.14971018411657305 0.17024156497751333 10.841997153306064 0.07912207807828901 0.03781286191883471 1.5306275702129777e-08 7.815130468268082 -0.3148830191132963 HANS(ph)VDTSFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HANSVDTSFSK 11 0 Q96BY6;A0A2R8YD85;Q96BY6-3;H7C0I3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 HANS(0.998)VDT(0.002)SFSK 76.358 0.020901 0.0 25837.0 28534.0 30322.0 32383.0 37206.0 32145.0 35731.0 31907.0 28336.0 21942.0 True False 30210.693795989097 31366.666945363522 31044.991476825355 30568.68549710253 29915.751385505755 30459.25961196162 32346.3010099619 31069.475058260963 28750.360393554718 25919.910907223577 1.165540032298866 1.2101379151199936 1.19772755346059 1.1793514879938647 1.1541610421650248 1.1751297958155011 1.2479325691257435 1.198672139324455 1.1091998154030047 1.0 14.661773138901323 -8.55412487444087 2.830604301301478 1.000508116679907 1.1914514528972497 0.8509255154913128 0.02498361248250954 0.10273068966320738 2.065487177690783 0.025912025982089474 0.0069427414037706095 2.7917410052906237e-09 8.55412487444087 0.19094333621734272 HANS(ph)VDTSFSK ddPTM_PC-9_Lapatinib_30min_R1 2 HANSVDTSFSK 11 0 Q96BY6;A0A2R8YD85;Q96BY6-3;H7C0I3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 HANS(0.999)VDT(0.001)SFSK;HANS(1)VDTSFSK 78.985 0.018465000000000002 0.0 60863.0 82830.0 88059.0 70660.0 73996.0 62698.0 70120.0 63857.0 76097.0 60914.0 True False 59995.08245909274 82638.21222405984 80819.12893756988 75856.57211485013 69643.70076173337 60016.552696176535 73750.47050020508 66824.02934143976 67526.15452306512 71442.90373719702 0.8397626541018667 1.1567028760203366 1.1312408190303034 1.0617789611952058 0.9748162115291111 0.8400631771203987 1.0322994537217642 0.935348730886586 0.9451765114623606 1.0 16.124503098336127 -6.326770481988483 4.562741797406241 0.9478778112649928 1.0613636318228752 0.1911759319461992 0.09216853361706849 0.3172432298087496 13.186266715483852 0.02874101950462412 0.03321092011939595 4.7122629651510205e-07 6.326770481988483 0.11348582055788237 HAPHCLS(ph)EEEGEQDRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HAPHCLSEEEGEQDRPR 17 1 E9PH18;A0A0J9YX62;O75190-4;O75190-3;O75190 E9PH18 DNAJB6 DnaJ homolog subfamily B member 6 1 HAPHCLS(1)EEEGEQDRPR;HAPHCLS(1)EEEGEQDRPR 71.637 0.006181100000000001 67732700.0 65120.5 57860.0 78820.9 85502.4 95363.7 56990.1 53757.8 77781.7 98848.5 63833.3 True False 76144.11446149745 63603.95841658143 80700.28918592802 80711.9777305209 76677.86755904848 54001.43883066273 48665.472011232 75740.0127915233 100293.9723095105 75405.7719858753 1.0097915909641566 0.8434892547548677 1.0702136860430853 1.070368694662254 1.016870002649286 0.716144632015412 0.6453812583517853 1.0044325626121913 1.3300569660409705 1.0 16.202387339338934 -8.009337775073497 24.974985045787683 1.1657672969722166 0.9101313406820697 0.2992632207995086 0.1546810212372362 545.4351814282466 1458823.571498597 0.09847904228025668 0.04311650453429003 9.787284775154864e-09 8.009337775073497 -0.2556359562901469 HAPS(ph)PEPAVQGTGVAGVPEESGDAAAIPAK ddPTM_PC-9_AZD4547_30min_R2 2 HAPSPEPAVQGTGVAGVPEESGDAAAIPAK 30 0 P13051 P13051 UNG Uracil-DNA glycosylase 1 HAPS(1)PEPAVQGTGVAGVPEESGDAAAIPAK;HAPS(1)PEPAVQGTGVAGVPEESGDAAAIPAK 138.53 4.7198e-17 290360000.0 648180.0 537930.0 796660.0 1011970.0 996320.0 809870.0 706590.0 887540.0 666290.0 759030.0 True False 854287.7570184547 711805.3527055095 786095.7678716034 778675.9512806435 857998.1657350453 759228.7008733404 769475.1411537944 750391.086640241 701508.7291420056 732456.5907307516 1.1663322684640676 0.9718055127271925 1.073231885438204 1.0631018426686285 1.1713979730580952 1.0365511219113734 1.0505402653092524 1.0244854045092238 0.9577478556676372 1.0 19.482383734731805 -7.777577472235682 1.595054048489312 0.9803363092314514 1.0781365084775327 0.3408269665425532 0.055610907493624365 0.48184772140721155 2.3062243354737424 0.04334749127785924 0.016783955509303942 1.6688700769062038e-08 7.777577472235682 0.0978001992460813 HAPS(ph)PEPAVQGTGVAGVPEESGDAAAIPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 HAPSPEPAVQGTGVAGVPEESGDAAAIPAK 30 0 P13051 P13051 UNG Uracil-DNA glycosylase 1 HAPS(1)PEPAVQGTGVAGVPEESGDAAAIPAK;HAPS(1)PEPAVQGTGVAGVPEESGDAAAIPAK;HAPS(0.999)PEPAVQGT(0.001)GVAGVPEESGDAAAIPAK;HAPS(1)PEPAVQGTGVAGVPEESGDAAAIPAK;HAPS(1)PEPAVQGTGVAGVPEESGDAAAIPAK;HAPS(1)PEPAVQGTGVAGVPEESGDAAAIPAK 133.34 2.0413e-15 260116700.0 471504.0 474981.0 535593.0 597249.0 665115.0 611181.0 617516.0 616830.0 525386.0 439864.0 True False 551320.3145715065 522133.97463992937 548363.5683677638 563787.0748373828 534790.4903179774 579129.5924373403 559020.4140513173 600638.8660854066 533068.7763173407 519607.8612384908 1.0610315118355382 1.0048615765654845 1.0553411702831699 1.0850241439642394 1.0292193983426245 1.1145512522789376 1.0758505706955361 1.1559464567256115 1.0259059111360742 1.0 18.987063732174093 -5.520702742651009 6.094264851208578 1.07613283786311 1.032047420795182 0.08238938233333182 0.04475229174892416 0.2749807295473258 42.945117754702245 0.011518959759040453 0.021827222662522575 3.0150690132521324e-06 5.520702742651009 -0.04408541706792812 HAPS(ph)PEPAVQGTGVAGVPEESGDAAAIPAK ddPTM_PC-9_Lapatinib_30min_R1 4 HAPSPEPAVQGTGVAGVPEESGDAAAIPAK 30 0 P13051 P13051 UNG Uracil-DNA glycosylase 1 HAPS(1)PEPAVQGTGVAGVPEESGDAAAIPAK;HAPS(1)PEPAVQGTGVAGVPEESGDAAAIPAK;HAPS(1)PEPAVQGTGVAGVPEESGDAAAIPAK;HAPS(0.999)PEPAVQGT(0.001)GVAGVPEESGDAAAIPAK 123.5 6.922699999999999e-18 344201700.0 449440.0 422664.0 450563.0 394422.0 439320.0 390396.0 354106.0 349654.0 430487.0 345988.0 True False 443030.90318279836 421685.34747639945 413519.44936347555 423429.10963322036 413480.0613363523 373699.67313752504 372439.87602603505 365900.20131468354 382001.02083092334 405791.5647999689 1.0917696216804955 1.0391673559904213 1.0190439753653233 1.0434645427929132 1.0189469106884304 0.9209153308096405 0.9178107884268756 0.9016949415768427 0.9413725024551142 1.0 18.630379350502956 -6.67225209958831 3.91688744585045 0.9287596740812051 1.0442044078857817 0.755187033136884 0.03032250888896013 0.1053513648962971 3.0725698250287827 0.010267162146403396 0.010094603845582008 2.126904060701969e-07 6.67225209958831 0.11544473380457665 HAPS(ph)PEPAVQGTGVAGVPEESGDAAAIPAKK ddPTM_PC-9_AZD4547_30min_R2 2 HAPSPEPAVQGTGVAGVPEESGDAAAIPAKK 31 1 P13051 P13051 UNG Uracil-DNA glycosylase 1 HAPS(1)PEPAVQGTGVAGVPEESGDAAAIPAKK;HAPS(1)PEPAVQGTGVAGVPEESGDAAAIPAKK 146.34 9.3623e-18 45019000.0 83691.0 85418.0 111152.0 124452.0 120971.0 108170.0 97220.0 120070.0 92231.0 111281.0 True False 110302.99711905916 113027.69805996936 109678.0518545734 95761.51416423278 104176.26476145611 101406.11280016415 105872.39165990429 101515.94043411435 97106.14236668163 107385.08606130003 1.0271724050776796 1.052545583429046 1.0213527397274185 0.8917580427282796 0.9701185572639744 0.9443221262799676 0.985913366028014 0.9453448719700674 0.9042795971802757 1.0 16.712434116182365 -5.605152829523766 7.533339717127359 0.9489352816777511 1.0391407757304543 0.604087401121191 0.03171008700216081 0.14143408563344298 10.99711636936241 0.008325270514382668 0.014485186404846646 2.4822594370803954e-06 5.605152829523766 0.09020549405270317 HAPS(ph)PEPAVQGTGVAGVPEESGDAAAIPAKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HAPSPEPAVQGTGVAGVPEESGDAAAIPAKK 31 1 P13051 P13051 UNG Uracil-DNA glycosylase 1 HAPS(1)PEPAVQGTGVAGVPEESGDAAAIPAKK;HAPS(1)PEPAVQGTGVAGVPEESGDAAAIPAKK 138.8 2.2719e-17 40442000.0 68200.0 63532.0 70270.0 86211.0 98007.0 93352.0 90685.0 89955.0 81662.0 71166.0 True False 79744.91298859997 69839.03709163936 71945.50330045907 81380.87716983329 78803.23189913624 88456.4567831961 82094.6602974557 87593.77656520109 82856.15226067437 84067.83245025382 0.9485781976808801 0.8307462563991502 0.8558030010233938 0.9680382471855629 0.9373767540131019 1.0522033720274542 0.9765288089952157 1.0419416560672443 0.985586874857319 1.0 16.359266255629272 -6.130145187191426 1.5875658774680967 1.0089217900528373 0.8750653137090946 0.6202448638168367 0.04180160975685885 0.230863280012625 1.1613866362155587 0.014163462226993788 0.021466098595899406 7.410624583611455e-07 6.130145187191426 -0.13385647634374276 HAPS(ph)PEPAVQGTGVAGVPEESGDAAAIPAKK ddPTM_PC-9_Lapatinib_30min_R1 4 HAPSPEPAVQGTGVAGVPEESGDAAAIPAKK 31 1 P13051 P13051 UNG Uracil-DNA glycosylase 1 HAPS(0.997)PEPAVQGT(0.002)GVAGVPEES(0.001)GDAAAIPAKK;HAPS(1)PEPAVQGTGVAGVPEESGDAAAIPAKK;HAPS(1)PEPAVQGTGVAGVPEESGDAAAIPAKK;HAPS(1)PEPAVQGTGVAGVPEESGDAAAIPAKK 123.03 4.046800000000001e-18 61562300.0 176010.0 157103.0 170927.0 161425.0 170451.0 166087.0 141294.0 142683.0 180676.0 129581.0 True False 173500.065123719 156739.23765587938 156874.04185730038 173296.7329980138 160425.40729955945 158983.84617770714 148609.5119631482 149312.57306990045 160326.36627737383 151978.9031941709 1.1416062458488219 1.0313223372564189 1.0322093301125839 1.1402683488023784 1.0555768197287037 1.0460915484735838 0.9778298753300126 0.9824559194188689 1.0549251436071891 1.0 17.213511545674486 -6.930477425776561 2.6281837241573744 1.0028803128460033 1.078910845648379 0.438205790654981 0.040643961355527954 0.27962308734453406 3.917453701534394 0.01630611036313956 0.01365620583481371 1.1736066838902932e-07 6.930477425776561 0.0760305328023756 HAPTYTIPLS(ph)PVLSPTLPAEAPTAQVPPSLPR ddPTM_PC-9_AZD4547_30min_R2 1 HAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPR 32 0 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 HAPT(0.004)Y(0.003)T(0.004)IPLS(0.597)PVLS(0.367)PT(0.025)LPAEAPTAQVPPSLPR 69.197 2.3431e-05 21965000.0 24684.0 17409.0 32569.0 46481.0 44190.0 38991.0 24933.0 40339.0 23008.0 29694.0 True False 32532.998540904657 23036.11879845003 32137.113779793443 35765.52357429137 38054.98127492339 36552.886606186636 27151.988698378886 34105.53444800312 24224.15590823704 28654.422098150175 1.1353569940956816 0.803928926556057 1.1215411593266122 1.248167680778328 1.3280666120075086 1.2756455698524227 0.9475671365967531 1.19023633878154 0.8453897909810181 1.0 14.806470179849924 -8.258689814122473 24.95786613481833 0.9226948909496996 1.1292149460617953 0.23253173889517842 0.15156285308233933 364.4340319995048 3308062.610753949 0.12248727750517337 0.04164865540675728 5.5120123996706934e-09 8.258689814122473 0.2065200551120957 HAPTYTIPLS(ph)PVLSPTLPAEAPTAQVPPSLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPR 32 0 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 HAPT(0.012)Y(0.001)T(0.015)IPLS(0.43)PVLS(0.43)PT(0.102)LPAEAPT(0.011)AQVPPSLPR 50.583 0.0044711 21669000.0 7279.2 8533.9 13149.0 16387.0 16216.0 22377.0 18514.0 13992.0 11328.0 12448.0 True False 8511.42478924658 9381.089193419706 13462.522027860185 15468.889517370806 13038.59120753 21203.51072754286 16760.21989024755 13624.72482574945 11493.650569529493 14704.723861686227 0.5788224838021918 0.6379643223265502 0.9155236204698375 1.0519673584402116 0.8866940535689075 1.4419523227355187 1.1397847418214364 0.9265542796930203 0.7816298134966465 1.0 13.84399207182499 -5.325683068267852 1.9922995735861029 1.0475005345602364 0.5659466340173172 0.5019268738713627 0.16674528752654827 0.31647870603407946 2.3088202711098913 0.05109672622410074 0.1809596091404944 4.724076607956765e-06 5.325683068267852 -0.48155390054291924 HAPTYTIPLSPVLS(ph)PTLPAEAPTAQVPPSLPR ddPTM_PC-9_AZD4547_30min_R2 1 HAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPR 32 0 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 HAPT(0.011)YT(0.014)IPLS(0.191)PVLS(0.663)PT(0.12)LPAEAPT(0.001)AQVPPSLPR 64.152 4.7491e-05 20478000.0 26294.0 29837.0 49593.0 71774.0 54908.0 52532.0 45493.0 70012.0 51752.0 65367.0 True False 34654.94505082432 39481.226755663956 48935.36441650942 55227.61319724586 47284.97198107024 49247.16573558503 49541.7888683813 59193.25411570925 54487.50506619799 63078.52122616633 0.5493937457184507 0.6259060293139258 0.7757849021389229 0.8755375383520604 0.7496208069230292 0.7807279685427414 0.7853987047469068 0.9384058624880162 0.8638044140387267 1.0 15.94486121842417 -3.5680637076809982 0.22916786836545694 0.9650179909317953 9.84924112071126e-30 0.7627385592217263 0.06265320806193057 11.260529931662528 0.3274286638094889 0.1082931671367844 3.3697844182817636 0.0002703561743175671 3.5680637076809982 -0.9650179909317953 HAPTYTIPLSPVLS(ph)PTLPAEAPTAQVPPSLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPR 32 0 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 HAPT(0.005)YT(0.01)IPLS(0.148)PVLS(0.736)PT(0.1)LPAEAPT(0.001)AQVPPSLPR 70.78399999999999 1.5863e-05 19386000.0 27457.0 25679.0 42751.0 47447.0 53225.0 49224.0 38387.0 40638.0 47321.0 38479.0 True False 32104.92779953059 28228.24141340123 43770.34597407036 44788.69841524945 42795.94332885942 46642.606786100456 34750.70546218711 39571.29555952014 48012.98010246338 45454.9381004036 0.7063023104027839 0.6210159466293628 0.962939293358794 0.9853428535381015 0.9415026203386125 1.0261284853820165 0.7645089161804084 0.8705609822218366 1.0562764379176894 1.0 15.472149412934163 -5.2643081248823 24.871329802931076 0.9432079574518125 0.6636591131226849 0.6662314630426587 0.08117945387823702 128.8615702689478 1117210.6836578855 0.021702658766425135 0.04860623140636274 5.441164740625222e-06 5.2643081248823 -0.27954884432912763 HAPTYTIPLSPVLS(ph)PTLPAEAPTAQVPPSLPR ddPTM_PC-9_Lapatinib_30min_R1 1 HAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPR 32 0 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 HAPT(0.027)Y(0.004)T(0.027)IPLS(0.129)PVLS(0.682)PT(0.128)LPAEAPT(0.002)AQVPPS(0.001)LPR 42.393 0.022415 12275000.0 7124.1 6286.8 7245.1 6415.7 5816.6 6410.2 5303.3 6478.8 7127.5 6904.2 True False 7022.509027600067 6272.243300859838 6649.435844894765 6887.531980147803 5474.47902387559 6136.050688906041 5577.878924753808 6779.8287000222235 6324.725894097625 8097.58177073178 0.8672353335143217 0.7745822738747119 0.8211631611956979 0.8505665240754186 0.6760634444795314 0.7577633499280519 0.6888326765547109 0.8372658519519376 0.781063541335015 1.0 12.98327541633134 -9.3575238421529 1.3515119346505649 1.0002256615693677 0.7798007173033833 0.529832353409001 0.060992990413962486 7.581505844429251 11.401721405833575 0.0638521744482035 0.017692264802819862 4.3901176385436475e-10 9.3575238421529 -0.22042494426598436 HAPTYTIPLSPVLSPT(ph)LPAEAPTAQVPPSLPR ddPTM_PC-9_Lapatinib_30min_R1 1 HAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPR 32 0 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 HAPT(0.007)YT(0.006)IPLS(0.268)PVLS(0.34)PT(0.377)LPAEAPT(0.002)AQVPPSLPR 64.984 0.00016106 13133000.0 27604.0 15331.0 26041.0 21664.0 23175.0 26163.0 23024.0 24655.0 28571.0 17914.0 True False 27210.36189804637 15295.502011433828 23900.009501166944 23257.242828985447 21811.892063803058 25044.069478931822 24216.07006270279 25800.561307502605 25353.033114032016 21010.411031095435 1.295089461018873 0.727996324717135 1.1375317439432717 1.106938973947949 1.0381468516499477 1.1919837951702406 1.1525747890825637 1.2279893653350114 1.2066890588913037 1.0 14.358816765583377 -6.758304852875983 24.94868106991504 1.1698922062930255 1.0494209357260926 0.09022025059806082 0.14465349596475421 159.6857105706866 1270987.753824414 0.046639951629267574 0.044758663168424584 1.744597103617106e-07 6.758304852875983 -0.12047127056693285 HAQDSDPRS(ph)PTLGIAR ddPTM_PC-9_AZD4547_30min_R2 3 HAQDSDPRSPTLGIAR 16 1 Q99618;F5GX58;F8WDL1;J3KMY0 Q99618 CDCA3 Cell division cycle-associated protein 3 1 HAQDS(0.002)DPRS(0.746)PT(0.252)LGIAR;HAQDSDPRS(0.818)PT(0.182)LGIAR;HAQDSDPRS(0.778)PT(0.222)LGIAR 107.74 0.00041233 54523000.0 87968.0 115843.0 179831.0 275898.0 238299.0 198618.0 188212.0 279193.0 206045.0 220590.0 True False 115939.99415193255 153286.98431666667 177446.32344051218 212293.97868160828 205215.29719015563 186198.38506187487 204962.50338504344 236050.13706689168 216936.1180507955 212867.21124237 0.5446587733040934 0.7201061329362489 0.8336010154164716 0.9973070885017185 0.9640531108217417 0.8747161386441519 0.9628655450917414 1.1089079228746304 1.0191147654196149 1.0 17.699594217458277 -4.408798186356619 0.654143706753371 1.0089872586804998 2.7750714271105738e-15 0.8748852437529633 0.055811746630302764 1.8173353148538787 0.41671347658464775 0.02770368349634884 1.526072233736226 3.901232321305029e-05 4.408798186356619 -1.008987258680497 HAQDSDPRS(ph)PTLGIAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HAQDSDPRSPTLGIAR 16 1 Q99618;F5GX58;F8WDL1;J3KMY0 Q99618 CDCA3 Cell division cycle-associated protein 3 1 HAQDSDPRS(0.943)PT(0.057)LGIAR;HAQDS(0.005)DPRS(0.794)PT(0.201)LGIAR;HAQDS(0.001)DPRS(0.771)PT(0.229)LGIAR 78.985 0.004389199999999999 45333300.0 86595.0 82367.0 134650.0 154741.0 191989.0 155888.0 153364.0 206581.0 174206.0 127482.0 True False 101253.82317078876 90543.85141546102 137860.56666296846 146071.363447091 154370.13365456785 147712.95885486004 138836.25166079332 201158.46764066254 176753.43318462695 150593.477453043 0.6723652636440448 0.6012468331750541 0.9154484576262951 0.9699713820118002 1.0250784845758176 0.9808722220450675 0.9219273902754804 1.3357714493536839 1.173712408890624 1.0 17.20029975938735 -5.112175754854722 0.5236941285843317 1.1332110605226375 0.3528130133308547 0.6772511912281053 0.11476917328405557 1.8745091280409536 0.5045066796952369 0.07655309427425995 0.8596810569223831 7.72367951860926e-06 5.112175754854722 -0.7803980471917829 HAQDSDPRS(ph)PTLGIAR ddPTM_PC-9_Lapatinib_30min_R1 1 HAQDSDPRSPTLGIAR 16 1 Q99618;F5GX58;F8WDL1;J3KMY0 Q99618 CDCA3 Cell division cycle-associated protein 3 1 HAQDS(0.011)DPRS(0.892)PT(0.096)LGIAR 54.103 0.029958 11813000.0 21965.0 23874.0 24035.0 24561.0 20808.0 18838.0 22355.0 16396.0 28683.0 19382.0 True False 21651.77507211232 23818.72121981419 22058.935077783008 26367.297873094158 19584.11435010199 18032.342653522803 23512.432516144938 17157.818016540783 25452.418494619724 22732.15287510838 0.9524735818498269 1.0477987435099294 0.9703847760912016 1.1599120425574054 0.8615160410761852 0.7932527443658075 1.0343249337325617 0.7547819210440261 1.1196659917983407 1.0 14.472446702295704 -6.29019264186079 24.983621580614322 0.9136492256370656 1.0292779819981364 0.16017713809784817 0.11562422540203848 1149.4628295372245 998761.5183673949 0.03387398548293102 0.038415437020287185 5.126339423211564e-07 6.29019264186079 0.11562875636107073 HAS(ph)APSHVQPSDSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HASAPSHVQPSDSEK 15 0 O60343-2;A0A3B3IRT3;O60343-3;O60343 O60343-2 TBC1D4 TBC1 domain family member 4 1 HAS(0.5)APS(0.5)HVQPSDSEK;HAS(0.5)APS(0.5)HVQPSDSEK;HAS(0.996)APS(0.004)HVQPSDSEK;HAS(0.8)APS(0.2)HVQPSDSEK 105.2 0.0006072 21243300.0 48879.399999999994 54381.8 80406.0 108792.0 149226.0 155068.0 158932.0 153740.0 146562.0 123756.0 True False 57153.717007844134 59780.46570720443 82323.1839814529 102696.73694842293 119986.23652780418 146935.96109838734 143876.8103919642 149704.48790099515 148705.19198193678 146191.98314804278 0.39094973456900745 0.40891753719947244 0.5631169521661629 0.7024785814994112 0.8207442976288167 1.0050890475272585 0.9841634766406164 1.024026657805137 1.0171911535761093 1.0 17.157504673622647 -5.964570996782511 0.8791517332803617 1.0244913709055385 0.34891889864069436 0.989425834561244 0.02516656177802429 0.06052458385559057 0.09314100407702738 0.0114561938320357 0.027756809322051754 1.0849981638298028e-06 5.964570996782511 -0.6755724722648442 down HAS(ph)PILPITEFSDIPR ddPTM_PC-9_AZD4547_30min_R2 7 HASPILPITEFSDIPR 16 0 G5E972;P42167;H0YJH7 G5E972 TMPO Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 HAS(1)PILPITEFSDIPR;HAS(1)PILPITEFSDIPR;HAS(0.999)PILPIT(0.001)EFSDIPR;HAS(1)PILPITEFSDIPR;HAS(0.865)PILPIT(0.106)EFS(0.029)DIPR;HAS(1)PILPITEFSDIPR;HAS(0.946)PILPIT(0.007)EFS(0.047)DIPR 134.4 2.7866e-06 51741700.0 32388.300000000003 36989.69999999999 52188.6 60528.9 52087.0 36066.399999999994 46316.2 60411.6 47698.0 40384.2 True False 42687.1056815096 48945.897151991885 51496.5450645745 46574.8972671828 44855.619137065725 33811.162306516104 50438.25207363159 51076.3753404642 50219.21890260304 38970.361449993805 1.095373614542556 1.2559775001009046 1.3214284689315523 1.1951363942812545 1.1510188119405511 0.8676122326938663 1.2942721133945143 1.3106466925128384 1.2886516068639395 1.0 15.250089692110937 -11.839098641875676 2.223276422823151 1.5974945574647424e-05 1.198130713110265 0.17100938757942974 0.13064288286568176 3481894.0046063215 1024239.6687234469 17134070.560776237 0.034762324811543927 1.4484428294594374e-12 11.839098641875676 1.1981147381646904 HAS(ph)PILPITEFSDIPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HASPILPITEFSDIPR 16 0 G5E972;P42167;H0YJH7 G5E972 TMPO Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 HAS(1)PILPITEFSDIPR;HAS(1)PILPITEFSDIPR;HAS(1)PILPITEFSDIPR;HAS(1)PILPITEFSDIPR 89.01100000000001 0.0021869 36559600.0 43509.6 39870.600000000006 43479.4 37814.5 57037.0 35374.5 37356.1 28282.5 28487.199999999997 27553.0 True False 50874.91592622855 43828.68967238422 44516.113792542725 35695.87616126311 45861.00929353042 33519.39894675179 33817.459773256785 27540.11434278577 28903.77140751243 32548.140790572023 1.56306672794549 1.346580437709049 1.3677006646547805 1.0967101436283229 1.409020858936884 1.029840664707371 1.0389982024119926 0.8461347921526476 0.8880314114864826 1.0 14.990287515910302 -6.417173324938413 0.5495374489285458 0.8791887943060195 1.505891698282728 0.747053561794637 0.11644649406216782 0.5175375652893361 0.32828447375531533 0.09239705802901509 0.16131147163819845 3.8267199019888126e-07 6.417173324938413 0.6267029039767085 HAS(ph)PILPITEFSDIPR ddPTM_PC-9_Lapatinib_30min_R1 6 HASPILPITEFSDIPR 16 0 G5E972;P42167;H0YJH7 G5E972 TMPO Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 HAS(1)PILPITEFSDIPR;HAS(1)PILPITEFSDIPR;HAS(1)PILPITEFSDIPR;HAS(0.982)PILPIT(0.017)EFS(0.001)DIPR;HAS(0.993)PILPIT(0.004)EFS(0.003)DIPR;HAS(0.999)PILPITEFS(0.001)DIPR 104.09 0.00092452 37969000.0 73014.8 76213.7 46444.6 28263.1 32632.4 39767.1 31610.199999999997 28713.9 48416.200000000004 11823.29 True False 71973.5955627254 76037.23186020582 42626.1042693406 30341.662656937733 30713.026389766834 38066.35383463781 33246.82148610354 30048.052619245558 42963.05771081156 13866.929922956364 5.190304989107565 5.483350120225822 3.0739395458236305 2.1880591324477563 2.2148396624491604 2.745117632102539 2.3975618014095708 2.166885733625995 3.0982386115391893 1.0 13.759360796252723 -5.361157431772313 3.288918803151964 2.3418549605906054 5.38065012339773 0.8423927768937263 0.5230401811776145 0.08250031253293295 1.6703931319957028 0.13224258512707396 0.3227728557990333 4.3535402921971265e-06 5.361157431772313 3.038795162807125 HAS(ph)SANQYK ddPTM_PC-9_AZD4547_30min_R2 5 HASSANQYK 9 0 Q8TED9;Q8TED9-4;Q8TED9-2 Q8TED9 AFAP1L1 Actin filament-associated protein 1-like 1 1 HAS(0.984)S(0.016)ANQYK;HAS(0.98)S(0.02)ANQYK;HAS(0.5)S(0.5)ANQYK;HAS(0.5)S(0.5)ANQYK;HAS(0.97)S(0.03)ANQYK 108.9 0.0024045000000000004 22026300.0 147012.0 97688.7 127055.0 147113.0 131164.4 146833.0 122712.3 125068.0 170213.0 237942.0 True False 193758.75796043914 129264.66186835241 125370.16768373772 113198.37072319267 112954.48712234823 137651.50929820247 133633.4569747758 105741.6143767288 179210.11168327328 229611.72300390803 0.8438539436296174 0.5629706540120877 0.5460094373387194 0.49299909099704814 0.49193693442396985 0.5994968701831466 0.5819975357813125 0.4605235873558993 0.7804919946540495 1.0 17.808836776240696 -8.523292475458081 4.228463581013657 0.9993900895413075 0.568217051427121 0.6460492799695075 0.10065755169790509 0.103966409260412 5.845645612681106 0.09694598095215928 0.025353833923218463 2.9971434140584388e-09 8.523292475458081 -0.4311730381141865 HAS(ph)SANQYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HASSANQYK 9 0 Q8TED9;Q8TED9-4;Q8TED9-2 Q8TED9 AFAP1L1 Actin filament-associated protein 1-like 1 1 HAS(0.959)S(0.041)ANQYK;HAS(0.5)S(0.5)ANQYK;HAS(0.978)S(0.022)ANQYK 87.667 0.0091605 11564400.0 28026.1 40690.7 52796.0 32548.0 73797.6 73324.4 37712.6 48248.8 68464.3 59179.4 True False 32770.36518929324 44730.203780532116 54054.85686994502 30724.44108203973 59337.49004050429 69479.13938377092 34140.189512420315 46982.32012382931 69465.46086576956 69908.15675612741 0.46876311306006413 0.6398424140486516 0.773226750327774 0.4394972276156709 0.8487920836977781 0.9938631285351563 0.48835774102180063 0.6720577727106406 0.9936674644147437 1.0 16.093173175995233 -5.7503478521899485 0.08604709082698943 1.305041185397493 1.0919407581358483e-15 0.35022258628840863 0.17109294847113177 72.11658215895763 1.4400569115477655 6.771566898643728 15.749761369979261 1.7768556509285295e-06 5.7503478521899485 -1.305041185397492 HAS(ph)SANQYK ddPTM_PC-9_Lapatinib_30min_R1 2 HASSANQYK 9 0 Q8TED9;Q8TED9-4;Q8TED9-2 Q8TED9 AFAP1L1 Actin filament-associated protein 1-like 1 1 HAS(0.5)S(0.5)ANQYK;HAS(0.912)S(0.088)ANQYK 131.42 0.0012343 10771100.0 28957.0 39538.0 30268.0 32023.0 47236.0 25851.0 42185.0 36257.0 41811.0 28346.0 True False 28544.06786993655 39446.4521902075 27779.48187785879 34378.078245596436 44457.671349549135 24745.412991624282 44369.13288720975 37941.63258268597 37101.804890651125 33245.56833132918 0.8585826413151691 1.1865176073117352 0.8355845086179685 1.0340649888424385 1.3372510557340707 0.7443221528057103 1.3345878898811967 1.141253841852101 1.1159924992374997 1.0 15.020874420237607 -6.006227909724024 24.9192576230489 1.118713738509757 0.974851774748218 0.12337054838691852 0.18079103636203547 594.7171597461826 2379615.6924820472 0.04925286878771881 0.07029159429794962 9.857620401554796e-07 6.006227909724024 -0.14386196376153892 HASAPS(ph)HVQPSDSEK ddPTM_PC-9_AZD4547_30min_R2 2 HASAPSHVQPSDSEK 15 0 O60343-2;A0A3B3IRT3;O60343-3;O60343 O60343-2 TBC1D4 TBC1 domain family member 4 1 HAS(0.452)APS(0.548)HVQPSDSEK;HAS(0.441)APS(0.559)HVQPSDSEK 71.143 0.019225 29904000.0 31150.5 34021.0 58788.0 93600.0 74363.0 72834.0 60492.0 86975.0 56519.0 75027.0 True False 41055.71102934901 45017.622933084516 58008.43270860318 72021.96610558449 64038.98104881484 68279.67846618456 65875.67081146808 73535.0122366711 59506.47895417463 72400.32756644137 0.5670652662679243 0.6217875587893177 0.8012178212228276 0.9947740366159303 0.884512310942884 0.9430852146839348 0.9098808392961255 1.0156723692885012 0.821908974093603 1.0 16.143708604170243 -5.3767658204073765 2.3985910199291745 0.9360070254758327 0.5765375843286765 0.8521302796895861 0.05694432993078324 0.09785871897149152 1.0722300795089583 0.014754171280847389 0.04180939557636022 4.199853868099375e-06 5.3767658204073765 -0.3594694411471562 HASAPS(ph)HVQPSDSEK ddPTM_PC-9_Lapatinib_30min_R1 2 HASAPSHVQPSDSEK 15 0 O60343-2;A0A3B3IRT3;O60343-3;O60343 O60343-2 TBC1D4 TBC1 domain family member 4 1 HAS(0.377)APS(0.623)HVQPSDSEK;HAS(0.45)APS(0.55)HVQPSDSEK 88.19 0.004251 23759000.0 55070.0 46006.0 73592.0 48390.0 91930.0 110236.0 91749.0 87840.0 126684.0 95541.0 True False 54284.69170139885 45899.475933600224 67541.54983333508 51948.762024307856 86522.85814133397 105521.46325266706 96499.3142886952 91921.36707568563 112415.51387833919 112055.13454962 0.48444626763051746 0.409615107046033 0.6027528332798217 0.46360001469905 0.7721454129620461 0.9416923524012216 0.8611770864097583 0.8203226692390542 1.0032160893846378 1.0 16.773849231447166 -6.411822342849977 2.9231536819617343 0.9093793188022374 0.4897612868489151 0.8925108145312424 0.07102129083243759 0.08346167294193833 1.3729858095119998 0.02347048772772678 0.02672990986955702 3.874160930856025e-07 6.411822342849977 -0.4196180319533223 HASSSPES(ph)PKPAPAPGSHR ddPTM_PC-9_AZD4547_30min_R2 2 HASSSPESPKPAPAPGSHR 19 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 HASS(0.002)S(0.001)PES(0.997)PKPAPAPGSHR;HAS(0.006)S(0.018)S(0.015)PES(0.962)PKPAPAPGSHR 71.143 0.0027489999999999997 5502100.0 4118.0 5367.8 14956.7 41178.0 23087.1 15769.300000000001 9086.4 22885.8 11354.2 19621.0 True False 5427.438340278942 7102.836376949865 14758.364385465835 31685.0482937581 19881.85467735424 14783.243178142096 9895.071997310795 19349.32547336597 11954.359831941285 18934.074762167602 0.2866492505418628 0.37513511836037144 0.7794605530424279 1.673440539965986 1.0500568381128614 0.7807745223273687 0.5226065768517115 1.0219313970402233 0.6313675203093331 1.0 14.208697303351864 -5.312062263743152 4.070144896136367 0.9510296058986131 0.31956447210193156 0.40830979459507255 0.29426037477116546 0.21746395854450315 7.597761060160237 0.08445409278127358 0.20025456537995984 4.874585993401611e-06 5.312062263743152 -0.6314651337966815 HASSSPES(ph)PKPAPAPGSHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HASSSPESPKPAPAPGSHR 19 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 HAS(0.01)S(0.036)S(0.032)PES(0.922)PKPAPAPGSHR;HAS(0.001)S(0.004)S(0.004)PES(0.99)PKPAPAPGSHR;HAS(0.005)S(0.016)S(0.014)PES(0.965)PKPAPAPGSHR 74.726 0.0017952000000000003 3997900.0 7752.0 9551.6 13600.800000000001 14201.600000000002 19995.100000000002 20200.300000000003 13760.199999999999 16499.3 17148.1 10066.4 True False 9064.260491020912 10499.819723674722 13925.094653321232 13405.930394208424 16077.203691026345 19140.960707404218 12456.734240779098 16066.21085745338 17398.85852148206 11891.358634421438 0.7622560860945663 0.8829789804910362 1.171026379863174 1.127367427587527 1.3520073008721063 1.6096529669871067 1.0475450807379647 1.3510828620496875 1.463151441006773 1.0 13.537625937624073 -5.241717419859719 1.1674283212917922 1.31482279018812 0.6841352405187606 0.5251586425267797 0.1741974491917498 0.6217290369199784 1.1905960867027017 0.05611907544569791 0.39431223281372507 5.73168850488532e-06 5.241717419859719 -0.6306875496693594 HATAEEVEEEERDR ddPTM_PC-9_AZD4547_30min_R2 1 HATAEEVEEEERDR 14 1 Q8TDN6 Q8TDN6 BRIX1 Ribosome biogenesis protein BRX1 homolog 0 106.79 0.00037975 6037600.0 17577.0 17268.0 17726.0 22743.0 18232.0 15679.0 18534.0 22134.0 13123.0 16985.0 False True 23166.12037568796 22849.54330585532 17490.94165803735 17499.952725847306 15700.801507227945 14698.589651416994 20183.490094884448 18713.69888872062 13816.654988864522 16390.360319831645 1.4133990909069845 1.3940842580628527 1.0671480868467575 1.067697865352789 0.9579290022215459 0.8967825822372142 1.2314244288127867 1.1417503046640063 0.8429744507902582 1.0 14.000559950028329 -5.2765222943892836 3.699761811711903 1.0289967246650604 1.4156978038812864 0.6701384495903098 0.10642565493649044 0.13302743771163889 4.033576209671103 0.029418461286694637 0.07676887593505803 5.290268390633987e-06 5.2765222943892836 0.386701079216226 HATAEEVEEEERDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HATAEEVEEEERDR 14 1 Q8TDN6 Q8TDN6 BRIX1 Ribosome biogenesis protein BRX1 homolog 0 ; 114.71 7.6398e-05 11683300.0 19921.8 17750.8 35336.0 21808.0 33233.0 34619.0 25667.0 24716.0 27331.0 14974.6 False True 23294.1672665145 19512.98211304966 36178.54425252626 20586.168462489957 26721.232215086635 32803.51869673354 23235.635947012175 24067.23118876666 27730.664169827924 17689.37644113162 1.3168450196102184 1.1030904440293194 2.045213090067061 1.163758854417427 1.510580788645212 1.854419165418306 1.313536179431645 1.3605471775028288 1.5676450926414875 1.0 14.110595572793045 -10.985427931045383 6.2566244090335505 0.9997950792028544 1.472295680435362 0.20390499630388415 0.2789578230790003 0.0007766532447119577 6.671529003931273e-05 0.26307812590241914 0.06377870577311094 1.0341226941321281e-11 10.985427931045383 0.4725006012325076 HATAEEVEEEERDR ddPTM_PC-9_Lapatinib_30min_R1 2 HATAEEVEEEERDR 14 1 Q8TDN6 Q8TDN6 BRIX1 Ribosome biogenesis protein BRX1 homolog 0 ; 80.17 0.0053674 11798100.0 31505.0 32021.0 16994.4 26694.0 20983.3 18985.2 26583.0 21496.6 17492.0 21925.7 False True 31055.732922690604 31946.857341864383 15597.18603228108 28657.165808573558 19749.103548755073 18173.247252662775 27959.33766838203 22495.41051319653 15521.866761074094 25715.52803084119 1.2076646019263066 1.2423177662752958 0.6065279318229452 1.1143914981720149 0.7679835905010213 0.7067032506922357 1.0872550481891639 0.8747792573505508 0.6035989905577044 1.0 14.650352157181288 -5.236561344158823 24.662607668121563 0.8512439761231634 1.2249913487709991 0.4367914583723568 0.17241486556863161 590.6660961551325 585548.7812920288 0.04226023402281102 0.11169443457711108 5.800142396404969e-06 5.236561344158823 0.37374737264783575 HAVPCTTRS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 HAVPCTTRSPR 11 1 Q96QZ7-7;Q96QZ7-6;Q96QZ7-2;Q96QZ7;Q96QZ7-4;Q96QZ7-3;Q96QZ7-5 Q96QZ7-7 MAGI1 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 1 HAVPCT(0.08)T(0.08)RS(0.84)PR 72.848 0.012367 603660.0 4479.4 2964.2 4100.3 8251.0 6545.0 5222.0 3009.1 5284.3 3741.5 5378.4 True False 5903.756022691959 3922.319681909678 4045.927342911574 6348.8594266792425 5636.33972492359 4895.467514490694 3276.9040706008855 4467.732856133836 3939.268051576363 5190.103853057547 1.137502483541633 0.7557304811153243 0.7795465095612825 1.2232625023368386 1.085978216332446 0.9432311285267867 0.6313754335899128 0.8608176218866692 0.7589959975956353 1.0 12.341547691605951 -7.0221666129854885 23.473230284302225 0.7992136119038483 0.9866904831944318 0.22341934022494303 0.16084685893925957 559.3209850506232 592288.2998989397 0.06331389455193227 0.04953920905432924 9.502401730311491e-08 7.0221666129854885 0.18747687129058344 HAVSEGT(ph)KAVTK ddPTM_PC-9_Lapatinib_30min_R1 1 HAVSEGTKAVTK 12 1 Q16778;P33778;P23527;P06899;Q96A08;A0A2R8Y619;Q8N257;U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 Q16778;Q8N257;U3KQK0 HIST2H2BE;HIST1H2BB;HIST1H2BO;HIST1H2BJ;HIST1H2BA;HIST3H2BB;HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B type 2-E;Histone H2B type 1-B;Histone H2B type 1-O;Histone H2B type 1-J;Histone H2B type 1-A;Histone H2B type 3-B;Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 1 HAVS(0.001)EGT(0.983)KAVT(0.016)K 65.842 0.025371 8975600.0 113120.0 78867.0 106400.0 88176.0 92527.0 104140.0 99120.0 92981.0 107600.0 77747.0 True False 111506.88805633261 78684.38830707387 97652.20271587752 94660.75718651296 87084.74377508105 99686.17496219688 104251.94860211521 97301.23670382904 95480.9549217685 91185.46535863425 1.2228581344381344 0.862904937728909 1.0709185102231968 1.0381123440474895 0.9550287804374855 1.0932243923977267 1.1432956797674962 1.0670695852803003 1.0471071737830147 1.0 16.476516261767017 -6.834876991747006 24.999999999944773 1.0789037335869123 1.0234032572126845 0.03910531064689682 0.09188007081674825 112.39906452284661 38260.19752371098 0.030704906429333434 0.027079188644769436 1.4625913757445066e-07 6.834876991747006 -0.055500476374227725 HAYGDQYR ddPTM_PC-9_AZD4547_30min_R2 4 HAYGDQYR 8 0 O75874;C9J4N6 O75874 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic 0 ;;; 153.04 9.4492e-05 17787300.0 49475.7 57435.7 64139.8 93467.09999999999 84220.4 73140.1 69027.7 71957.59999999999 63071.700000000004 64073.4 False True 65207.94344151016 76000.66680867002 63289.264343799194 71919.70414729984 72527.85120992451 68566.63798479506 75171.03157562604 60838.20634114952 66405.54129857251 61830.20976842509 1.0546291802297907 1.2291833893709572 1.0235977620137269 1.163180659044556 1.1730164183748637 1.1089504344494407 1.2157654301540752 0.9839560074114101 1.0739983180921362 1.0 15.916024279719233 -7.773637842871563 24.999337257582877 1.0217328547778033 1.1385730234360143 0.4159821909340491 0.0646028493870275 220.06376348244817 450988.37763250445 0.03260361338725017 0.015845109485328187 1.6840778241564208e-08 7.773637842871563 0.11684016865821101 HAYGDQYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HAYGDQYR 8 0 O75874;C9J4N6 O75874 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic 0 ; 122.18 0.0028033000000000003 6700200.0 26202.0 26406.0 30510.0 34685.0 33846.0 30488.0 33256.0 24192.0 23974.8 27860.0 False True 30637.481086910488 29027.413168825584 31237.474109819323 32741.71190028723 27214.119265543948 28889.155608943405 30105.75092741018 23556.98563354277 24325.386094134516 32910.79746036134 0.9309249076632404 0.8820027288547775 0.949155794460544 0.9948623074151345 0.826905495022458 0.8778017501319526 0.9147681992109236 0.7157828874221429 0.7391308619437944 1.0 15.006273364327413 -6.928713844684079 1.1822079475263654 0.8142134313343011 0.9295810589918801 0.16414139453742282 0.08464576201837734 0.7106190506416986 2.061590643280279 0.04740542672646068 0.03647285486274902 1.1783821502045459e-07 6.928713844684079 0.11536762765757902 HAYGDQYR ddPTM_PC-9_Lapatinib_30min_R1 3 HAYGDQYR 8 0 O75874;C9J4N6 O75874 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic 0 ;; 107.01 0.0032034999999999998 5598100.0 17280.100000000002 13694.4 15074.3 13437.800000000001 16923.5 16339.7 13641.3 17239.2 19832.4 12853.8 False True 17033.682605217764 13662.691458181434 13834.949242480734 14426.0606391867 15928.093002881153 15640.889120701064 14347.57976660647 18040.196166793725 17598.66626756952 15075.562203388088 1.1298870566425447 0.9062807259759026 0.9177070185396775 0.9569169258539878 1.0565505145341423 1.0374995578729345 0.9517110919672361 1.1966516355018166 1.1673638455496131 1.0 13.879924184189973 -7.756253701436389 24.999797634845635 1.136505813117145 0.9901774317774629 0.3419295926122742 0.08015216367037097 123.69035130150236 596310.6467641403 0.038901022519105974 0.021591643670316647 1.7528562381684352e-08 7.756253701436389 -0.14632838133968218 HCAPS(ph)PDRSPELSSSR ddPTM_PC-9_AZD4547_30min_R2 1 HCAPSPDRSPELSSSR 16 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 HCAPS(0.808)PDRS(0.038)PELS(0.051)S(0.051)S(0.051)R 57.173 0.027654 2525400.0 3107.5 4260.0 5552.0 6437.5 8430.4 6242.9 4134.6 8128.0 6214.2 7016.6 True False 4095.620359984657 5636.961691159583 5478.376852387642 4953.433833383547 7259.984479296537 5852.5304761037805 4502.571390218477 6872.004362858999 6542.669925459264 6770.950969686819 0.6048811132026399 0.8325214163262967 0.809100062445296 0.7315713635440283 1.0722252327330524 0.8643587145004066 0.6649836057558599 1.0149245495388448 0.9662852315354878 1.0 12.725142757000308 -3.0476822962815016 0.27480875666733323 0.9631705263904567 2.452270657544435e-32 0.37395985015475564 0.11809186304786787 28.91219338968516 0.8435487474436917 0.14493195160368627 11.20204483912657 0.0008960200001883825 3.0476822962815016 -0.9631705263904567 HCAPS(ph)PDRSPELSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HCAPSPDRSPELSSSR 16 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 HCAPS(0.932)PDRS(0.063)PELS(0.001)S(0.001)S(0.001)R 57.288000000000004 0.024503 3067500.0 6336.3 6080.2 10493.0 7314.7 10775.0 10052.0 10170.0 7713.6 10486.0 8210.9 True False 7408.910442370467 6683.802073358074 10743.192914924097 6904.881073577369 8663.716098984693 9524.855424465333 9206.623975576182 7511.126173234777 10639.337912437002 9699.47117255136 0.7638468438709343 0.6890893281143655 1.1076060461240789 0.7118822202510965 0.8932153047170486 0.9819973950146711 0.9491882404506864 0.774385122612725 1.0968987610938399 1.0 13.243690376545832 -2.650710576460146 0.28636475579951565 0.9737215668725866 5.978116754780418e-26 0.24051226873974896 0.12782805474795497 44.49376799060106 1.1198712199559573 0.1384650908791717 19.214586804822865 0.0022350612213278007 2.650710576460146 -0.9737215668725866 HCAPS(ph)PDRSPELSSSR ddPTM_PC-9_Lapatinib_30min_R1 1 HCAPSPDRSPELSSSR 16 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 HCAPS(1)PDRSPELSSSR 61.657 0.019148 4318500.0 6644.1 7951.8 9510.8 7114.6 5953.6 7948.8 8190.8 5248.5 9726.0 6671.6 True False 6549.353915621285 7933.388095657136 8728.85873674969 7637.831417609859 5603.420953227953 7608.848353557814 8614.879546107797 5492.36447059126 8630.555460679554 7824.777170651796 0.8370019711469598 1.0138803856821257 1.1155408705424623 0.9761084885914567 0.7161125270435265 0.9724044771646839 1.1009744249867484 0.701919601134629 1.1029777938022276 1.0 12.933833953081406 -6.014579620461495 24.67567109924324 0.9204857353022668 1.0003999652155564 0.026958539648463398 0.14302979064120966 1778.8885100696696 3010735.2553254166 0.041048234011632094 0.05511878452356649 9.669864299837502e-07 6.014579620461495 0.07991422991328956 HCAPSPDRS(ph)PELSSSR ddPTM_PC-9_AZD4547_30min_R2 1 HCAPSPDRSPELSSSR 16 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 HCAPS(0.01)PDRS(0.359)PELS(0.217)S(0.054)S(0.359)R 58.32 0.022754 4888000.0 4291.3 5467.9 6308.9 9113.5 9453.4 6752.1 5829.2 8874.5 5880.3 8265.9 True False 5655.844135415011 7235.291744387672 6225.2398638379655 7012.523377171406 8140.958587561902 6329.890119607928 6347.987507343289 7503.149940722465 6191.12065312962 7976.513356944145 0.7090622032859984 0.90707448487989 0.7804462407648868 0.8791464469957272 1.0206161794331599 0.7935660402420426 0.7958348746218666 0.9406553471374078 0.7761687815315688 1.0 12.961542547167062 HCCGVAQMR ddPTM_PC-9_AZD4547_30min_R2 1 HCCGVAQMR 9 0 O00170;V9GYQ3 O00170 AIP AH receptor-interacting protein 0 68.383 0.029317000000000003 303150.0 0.0 0.0 619.77 0.0 655.95 747.66 0.0 810.18 520.49 512.63 False True 0.0 0.0 611.5514448494757 0.0 564.8826650211812 700.9087020076811 0.0 684.9852970842899 548.0020387986052 494.68297973242846 0.0 0.0 1.236249213951652 0.0 1.1419084305805778 1.4168846124174297 0.0 1.3846955022685337 1.107784300755641 1.0 8.950360452161819 -5.416816921838441 0.9664549397898058 0.9628331657044752 2.3126669846694216e-22 0.3037508768158973 0.5057410418299638 1.2954618791249424 1.8107900166382591 0.18727549770090923 1.0598465357640403 3.829861582734142e-06 5.416816921838441 -0.9628331657044752 HCCPAGFR ddPTM_PC-9_AZD4547_30min_R2 1 HCCPAGFR 8 0 K7EQ05;P28799-3;P28799-2;P28799 K7EQ05 GRN Granulins;Acrogranin;Paragranulin;Granulin-1;Granulin-2;Granulin-3;Granulin-4;Granulin-5;Granulin-6;Granulin-7 0 73.616 0.024730000000000002 712990.0 1222.1 2142.4 4235.6 3953.4 2074.2 2322.1 1003.6 3346.4 2384.1 2427.1 False True 1610.702378740868 2834.8889030845735 4179.433176508124 3042.0047094211272 1786.2331332981682 2176.898719915518 1092.9184557691838 2829.2907726219682 2510.1186587633842 2342.127967751743 0.6877089556669332 1.2103902699244233 1.7844597878740367 1.2988208805436068 0.762653944571957 0.9294533645850137 0.466634817062664 1.2080000800886481 1.0717256671388877 1.0 11.193604187741697 -6.25030007968301 24.185575211063576 0.8959745965141561 1.2813564544035922 0.22064988653297113 0.30873436102036217 705.2228423723911 1531172.935343225 0.09614720739582008 0.12284980050436493 5.619529045947404e-07 6.25030007968301 0.38538185788943613 HCCPAGFR ddPTM_PC-9_Lapatinib_30min_R1 2 HCCPAGFR 8 0 K7EQ05;P28799-3;P28799-2;P28799 K7EQ05 GRN Granulins;Acrogranin;Paragranulin;Granulin-1;Granulin-2;Granulin-3;Granulin-4;Granulin-5;Granulin-6;Granulin-7 0 ; 105.39 0.0032253 1914750.0 10029.3 6378.7 6384.200000000001 7282.3 7459.0 7126.5 6436.5 5521.4 8838.8 6741.8 False True 9886.280342851629 6363.930512056161 5859.315719724669 7817.864635040653 7020.27628495823 6821.7162076828945 6769.750475963622 5777.944400861692 7843.281267309727 7907.111147116175 1.2503024377565861 0.8048363547257292 0.7410185098841866 0.9887131329742253 0.8878433797555274 0.8627317968295997 0.8561597718823818 0.7307276062470657 0.9919275347697968 1.0 12.948934988845018 -4.756013620544578 24.882105553344353 0.8643458796672567 1.2503030858566309 0.5920390636794766 0.09347351957501672 109.0399867337516 499992.07140316616 0.022506776800364676 0.1889153025588602 1.7538254966921386e-05 4.756013620544578 0.3859572061893741 HCDSINSDFGSESGGCGDS(ph)SPGPSASQGPR ddPTM_PC-9_AZD4547_30min_R2 1 HCDSINSDFGSESGGCGDSSPGPSASQGPR 30 0 Q8TD19;G3V459 Q8TD19 NEK9 Serine/threonine-protein kinase Nek9 1 HCDSINSDFGSES(0.001)GGCGDS(0.5)S(0.5)PGPSASQGPR 132.69 1.9042e-15 17669000.0 12899.0 14306.0 20631.0 33374.0 28335.0 19683.0 17494.0 25096.0 19059.0 22742.0 True False 17000.613684132604 18930.134730922295 20357.41945994408 25680.139923160004 24401.17434770207 18452.218898452764 19050.93210963142 21217.989848709327 20066.41983028034 21945.809502126052 0.7746633216006741 0.8625853937667869 0.9276221712382907 1.1701614342670832 1.1118830838907148 0.8408083054154444 0.8680897420432733 0.9668355977779622 0.9143622534560122 1.0 14.421657866569216 -5.137760218085348 2.593565910072886 0.9780947724570228 0.7872858946727426 0.31889098023377105 0.09619219656946758 0.41396034863536746 5.09557369901166 0.02902287442304222 0.1192419682433008 7.281817360044449e-06 5.137760218085348 -0.19080887778428024 HCDSINSDFGSESGGCGDS(ph)SPGPSASQGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HCDSINSDFGSESGGCGDSSPGPSASQGPR 30 0 Q8TD19;G3V459 Q8TD19 NEK9 Serine/threonine-protein kinase Nek9 1 HCDSINSDFGSES(0.003)GGCGDS(0.498)S(0.498)PGPS(0.001)ASQGPR 126.99 2.9771e-17 8423300.0 16503.0 17770.0 25765.0 25105.0 26949.0 26759.0 27177.0 31054.0 23820.0 21157.0 True False 19296.631950892446 19534.088162161275 26379.33531430663 23698.44824150816 21668.536905015186 25355.710933472747 24602.597815558893 30238.865404432752 24168.322436987357 24992.596621280147 0.7720939221842269 0.7815949842334037 1.055485979069727 0.9482187305551887 0.8669982248489273 1.0145288749982635 0.9843954267085163 1.209912913918101 0.9670192658736806 1.0 14.60921317845441 -3.5001771100594827 0.4185958479892875 1.0465483614354683 1.427401711504581e-15 0.47679288536120057 0.08938826826533346 13.311461692478094 0.7898641487078861 0.06581379157051157 8.69345610532484 0.00031609883115310864 3.5001771100594827 -1.046548361435467 HCDSINSDFGSESGGCGDS(ph)SPGPSASQGPR ddPTM_PC-9_Lapatinib_30min_R1 1 HCDSINSDFGSESGGCGDSSPGPSASQGPR 30 0 Q8TD19;G3V459 Q8TD19 NEK9 Serine/threonine-protein kinase Nek9 1 HCDSINSDFGS(0.001)ES(0.189)GGCGDS(0.405)S(0.405)PGPSASQGPR 112.39 5.4728e-16 11922000.0 12047.0 13514.0 18924.0 15111.0 18142.0 17229.0 16856.0 15794.0 18422.0 15568.0 True False 11875.207570850775 13482.709163297686 17368.141768752484 16222.31334881827 17074.92322854433 16492.155832760625 17728.721202958564 16527.846898831733 16347.12036773994 18258.90805694394 0.65037884707101 0.7384181530050564 0.9512147010427224 0.8884602134051963 0.9351557702844483 0.9032388892767653 0.9709628389424009 0.9051936100059458 0.8952956177203084 1.0 14.156312869519105 -5.120736987949275 3.2056281966832634 0.9272437902463274 0.6607967731242902 0.8819987720386699 0.0351816227757432 0.07405257956284989 1.384639027599125 0.00878688098506022 0.03152085502865063 7.572913776110369e-06 5.120736987949275 -0.2664470171220372 HCDSINSDFGSESGGCGDSS(ph)PGPSASQGPR ddPTM_PC-9_AZD4547_30min_R2 2 HCDSINSDFGSESGGCGDSSPGPSASQGPR 30 0 Q8TD19;G3V459 Q8TD19 NEK9 Serine/threonine-protein kinase Nek9 1 HCDSINSDFGSESGGCGDS(0.253)S(0.747)PGPSASQGPR;HCDSINSDFGSESGGCGDS(0.253)S(0.746)PGPSASQGPR 145.36 2.9616e-20 6577200.0 7442.9 6080.6 17933.4 32548.0 23164.0 17603.0 11722.4 21901.0 16505.6 19758.2 True False 9809.587378062688 8046.035037386136 17695.591398524597 25044.5614615872 19948.078439744848 16502.281627265347 12765.67089070214 18516.703684913267 17378.052319149756 19066.471431928032 0.5144941167056167 0.42199916571414114 0.9280999613222712 1.3135394008798331 1.046238603244673 0.8655131436449859 0.6695350493288026 0.9711657320035556 0.9114456432693199 1.0 14.218750253158987 -5.281682654724456 7.654164623081823 0.9642591899303792 0.46764397165635485 0.6253406024454156 0.15326510115417624 0.1217596533254842 37.49051547388002 0.04471069785031539 0.09797710890989438 5.227780509686322e-06 5.281682654724456 -0.49661521827402433 HCECAEEGTR ddPTM_PC-9_AZD4547_30min_R2 1 HCECAEEGTR 10 0 A0A0C4DGH5;Q86VP6-2;Q86VP6 A0A0C4DGH5 CAND1 Cullin-associated NEDD8-dissociated protein 1 0 126.71 0.00010085 0.0 4140.1 4700.0 6614.7 6997.0 6856.9 7089.2 5441.8 7927.8 6599.4 8473.2 False True 5456.565680570389 6219.183086490622 6526.984756031799 5383.949752572374 5904.937793709484 6645.911203318155 5926.109657836532 6702.740672720665 6948.230811057877 8176.5558470413625 0.6673428008866122 0.760611583022575 0.7982559989966374 0.6584618087725193 0.7221791062365397 0.8128008085119284 0.7247684439140545 0.8197511028003327 0.8497747634870069 1.0 12.997277559522752 -8.643050147852819 0.6351588909273564 1.0042171959265052 0.7263535811812142 0.7618652326473704 0.04641589417649306 0.46617715423899264 0.4189127992359783 0.04901536822705898 0.01973114366761102 2.2748347411246713e-09 8.643050147852819 -0.277863614745291 HCECAEEGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HCECAEEGTR 10 0 A0A0C4DGH5;Q86VP6-2;Q86VP6 A0A0C4DGH5 CAND1 Cullin-associated NEDD8-dissociated protein 1 0 132.32 0.00012628 1397900.0 4800.6 7508.1 8899.0 6444.3 7049.9 4740.8 6464.6 5165.5 5860.2 6121.2 False True 5613.246763828044 8253.45454869573 9111.185909645443 6083.24676370249 5668.522703130601 4492.184102298575 5852.226288349051 5029.911098299653 5945.894338590817 7230.925104607462 0.7762833500033555 1.141410598131728 1.2600304632999033 0.8412819488098854 0.7839277300104635 0.621246111294419 0.8093329973256229 0.6956110076558047 0.822286810134731 1.0 12.819964518069535 -5.935199418083283 7.650841717377277 0.7702408946679438 1.0668959088916548 0.40626099898076307 0.14572996982245076 0.21029587557728105 21.29536081612612 0.040545745836736286 0.060318245954304656 1.1609154256505286e-06 5.935199418083283 0.296655014223711 HCECAEEGTR ddPTM_PC-9_Lapatinib_30min_R1 2 HCECAEEGTR 10 0 A0A0C4DGH5;Q86VP6-2;Q86VP6 A0A0C4DGH5 CAND1 Cullin-associated NEDD8-dissociated protein 1 0 ; 123.51 0.00037671 3630100.0 10067.5 19852.7 15349.7 10308.6 18477.2 14554.1 14280.3 17466.9 15482.4 13380.5 False True 9923.935603846618 19806.732292896246 14087.706917555484 11066.72883248151 17390.407423572884 13931.655070264173 15019.664059955467 18278.47594005344 13738.609075100243 15693.301596604464 0.632367608737848 1.2621137859978298 0.8976891720862371 0.7051880551939436 1.1081420513409121 0.8877453214356463 0.957074836515297 1.1647310687005674 0.8754441498832116 1.0 13.937861281630246 -7.538121598699517 24.920689366361174 1.0242331586464875 0.9290704459042607 0.05164734272007243 0.18063721454964643 781.8024386475751 1278160.0627487488 0.08151396273177901 0.047082930589604666 2.8965324701088293e-08 7.538121598699517 -0.09516271274222676 HCGLSLSS(ph)TPPGK ddPTM_PC-9_AZD4547_30min_R2 1 HCGLSLSSTPPGK 13 0 D6R9S4;Q09GN1;Q71F23-3;Q71F23 D6R9S4 CENPU;MLF1IP Centromere protein U 1 HCGLS(0.002)LS(0.07)S(0.549)T(0.379)PPGK 66.285 0.021418 15474000.0 35539.0 39476.0 91004.0 151160.0 109420.0 108100.0 67284.0 112590.0 81491.0 104790.0 True False 46839.6627428784 52235.845004745475 89797.2274990427 116312.39739871939 94228.92172668285 101340.48991123027 73272.14565362071 95191.80256081397 85798.4478928263 101121.33399559364 0.46320257943708926 0.5165660196593298 0.8880146646696295 1.1502260977271888 0.9318401765822123 1.0021672569672209 0.7245963117616065 0.9413622111132548 0.8484702930893392 1.0 16.62572787526515 -5.266103882226501 4.261981845916489 0.9388559778238477 0.4777384331422724 0.7498232300773208 0.10356036661089883 0.09566867588645242 4.41777614471473 0.02833849205763307 0.07192079816256022 5.418712605577749e-06 5.266103882226501 -0.4611175446815753 HCGLSLSST(ph)PPGK ddPTM_PC-9_AZD4547_30min_R2 1 HCGLSLSSTPPGK 13 0 D6R9S4;Q09GN1;Q71F23-3;Q71F23 D6R9S4 CENPU;MLF1IP Centromere protein U 1 HCGLSLS(0.001)S(0.005)T(0.994)PPGK 132.56 0.00026812 0.0 13685.0 14016.0 40580.0 55500.0 39419.0 37718.0 24885.0 48531.0 31224.0 41522.0 True False 18036.545334316976 18546.397902181387 40041.88268549902 42705.3324664523 33946.35227146877 35359.487497426235 27099.716791367206 41031.64908143581 32874.43689494063 40068.3274183132 0.45014470272281404 0.46286928097988855 0.9993400090665602 1.065812705896325 0.8472116122310015 0.8824797483626733 0.676337609714682 1.0240419734286768 0.8204594255141129 1.0 15.29017466781409 -5.253790169596599 24.750352632619602 0.9086761763915526 0.4565069056243003 0.7350256711702539 0.10994073399178751 255.40154336586858 826390.3756949126 0.02885366820127447 0.07324357782950375 5.574550195850244e-06 5.253790169596599 -0.45216927076725233 HCGLSLSST(ph)PPGK ddPTM_PC-9_Lapatinib_30min_R1 2 HCGLSLSSTPPGK 13 0 D6R9S4;Q09GN1;Q71F23-3;Q71F23 D6R9S4 CENPU;MLF1IP Centromere protein U 1 HCGLSLS(0.011)S(0.101)T(0.888)PPGK;HCGLSLS(0.003)S(0.106)T(0.89)PPGK 92.939 0.0091624 18341400.0 101373.0 82612.0 189957.0 107955.0 164279.0 176890.0 131267.0 144705.0 185208.0 117708.0 True False 99927.40243046856 82420.7169896661 174339.46871522508 115894.37082732275 154616.43220494068 169324.82705073015 138063.3629656361 151428.5225715745 164347.924713298 138053.67096394897 0.7238300997918656 0.5970193795946888 1.2628383403202057 0.8394877877429797 1.119973348954385 1.2265144843192708 1.0000702045923116 1.0968815353784993 1.1904639953849214 1.0 17.074869725354972 -5.25227871644392 24.99945113686973 1.0889863028848614 0.6604246900137866 0.670288420540174 0.12106752698308333 360.39217363800236 983505.2736444464 0.029813725103948998 0.07648474124624768 5.593984820426573e-06 5.25227871644392 -0.42856161287107486 HCGYTQLS(ph)PFSEDSAK ddPTM_PC-9_AZD4547_30min_R2 1 HCGYTQLSPFSEDSAK 16 0 Q70EL1-7;Q70EL1;H7C296;R4GN32;H7C1E9;Q70EL1-6 Q70EL1-7 USP54 Inactive ubiquitin carboxyl-terminal hydrolase 54 1 HCGYT(0.001)QLS(0.999)PFSEDSAK 100.46 0.0010052 5178400.0 15407.0 19834.0 17024.0 31318.0 35162.0 37717.0 31586.0 40779.0 28627.0 39203.0 True False 20306.10551449191 26244.952624990423 16798.250636715995 24098.118958276656 30280.363240299987 35358.55002758433 34397.092809810114 34477.54255819725 30140.164776821184 37830.51490246452 0.536765242737128 0.6937508699698047 0.4440397039275204 0.6370021402142415 0.8004216521601542 0.9346568535677225 0.9092419941545461 0.9113685776439475 0.7967156898215431 1.0 15.20726279226179 -6.327707216307704 2.5185585218445725 0.903320661033573 0.5684929919577609 0.8155467915105805 0.07501108617195879 0.11877053253001142 1.479234399388317 0.024325804264799585 0.02944493613842472 4.702109989245415e-07 6.327707216307704 -0.3348276690758121 HCGYTQLS(ph)PFSEDSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HCGYTQLSPFSEDSAK 16 0 Q70EL1-7;Q70EL1;H7C296;R4GN32;H7C1E9;Q70EL1-6 Q70EL1-7 USP54 Inactive ubiquitin carboxyl-terminal hydrolase 54 1 HCGYTQLS(1)PFSEDSAK 94.057 0.0015030999999999998 3915900.0 12359.0 19003.0 15645.0 20146.0 27716.0 22488.0 30181.0 21561.0 23670.0 21873.0 True False 14451.134598623254 20889.49225354816 16018.036133992899 19017.284934213243 22285.24876097074 21308.689692138523 27322.037188482278 20995.04659576785 24016.128970759477 25838.40175342726 0.5592890278790724 0.8084668878862576 0.61993138301862 0.736008562591947 0.8624855737454727 0.8246907024468761 1.0574197835149857 0.8125520609254797 0.9294742453477768 1.0 14.657229213756374 -6.366242234341437 1.3239322276505154 0.9302523048156778 0.6691188556136883 0.6423033229500046 0.08826656243372367 0.28452690932735136 1.0173614206088983 0.03443173441697699 0.044337937955056896 4.302865446941592e-07 6.366242234341437 -0.26113344920198944 HCNGVDWR ddPTM_PC-9_AZD4547_30min_R2 1 HCNGVDWR 8 0 O15371-2;O15371-3;O15371 O15371-2 EIF3D Eukaryotic translation initiation factor 3 subunit D 0 95.35799999999999 0.0054144 5808300.0 5415.1 5094.3 7294.9 11286.0 9775.4 7775.1 7874.6 9733.1 5622.9 8906.1 False True 7136.989158922901 6740.932850533864 7198.164859597013 8684.18706696182 8418.254445686485 7288.92176788904 8575.424144878445 8229.073039387666 5920.115014622137 8594.300149805864 0.8304328490417127 0.7843492469466679 0.8375510203421987 1.0104588989899297 0.9795159930359943 0.8481111481839145 0.9978036600306722 0.9575035658457369 0.6888420128957058 1.0 13.069164447749598 -5.571659422208143 9.857161746240694 0.9261850032294773 0.8082543007275625 0.22984174372472976 0.0921937027410294 0.5405465959458534 105.11775098350793 0.02479505721457644 0.04303028174625428 2.6812701776989167e-06 5.571659422208143 -0.11793070250191473 HCNGVDWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HCNGVDWR 8 0 O15371-2;O15371-3;O15371 O15371-2 EIF3D Eukaryotic translation initiation factor 3 subunit D 0 ;;; 107.57 0.0031958999999999998 14151000.0 16376.6 18606.300000000003 25041.8 22893.9 26535.7 27917.5 22644.4 25104.5 24067.0 16700.800000000003 False True 19148.83492740623 20453.410499247144 25638.891483555348 21611.229006025238 21336.220073116307 26453.45715405003 20499.358500741128 24445.533475416447 24418.934344709254 19728.522836539934 0.9706167606192978 1.0367431291594025 1.299584956055027 1.0954306708659542 1.0814910092304881 1.34087368695717 1.039072142936799 1.2390959869605624 1.237747729367859 1.0 14.267995318571954 -5.053295208351153 7.879835353165634 1.1713417712726462 0.9864358442859963 0.2776336429830847 0.10730198785541534 0.29879073296673075 40.956654435505115 0.025812878594531272 0.07029579915376397 8.84514163704705e-06 5.053295208351153 -0.18490592698664987 HCNGVDWR ddPTM_PC-9_Lapatinib_30min_R1 2 HCNGVDWR 8 0 O15371-2;O15371-3;O15371 O15371-2 EIF3D Eukaryotic translation initiation factor 3 subunit D 0 ; 129.42 0.0031769000000000003 20288100.0 20969.9 17217.8 14594.8 18143.5 19173.3 14102.2 16704.4 11380.6 16436.5 13959.6 False True 20670.86538059131 17177.933241958486 13394.871881557221 19477.83351494173 18045.56419015814 13499.081779833818 17569.272096743065 11909.384222922901 14585.248285981846 16372.498260002225 1.262535811720923 1.0491943849475878 0.8181324357981884 1.1896677712604065 1.1021875772155794 0.82449737147396 1.073096592696824 0.7274017705665209 0.8908382859085956 1.0 13.998986857275975 -6.752701095391272 24.993772603218016 0.8967500231490131 1.0734527198699526 0.29786802077541574 0.13840299509248816 260.61317411690004 745420.7192370872 0.046516075180252255 0.045835048332177594 1.7672537204131156e-07 6.752701095391272 0.17670269672093952 HCSQVDSVR ddPTM_PC-9_AZD4547_30min_R2 4 HCSQVDSVR 9 0 Q14247-3;Q14247;Q14247-2 Q14247-3 CTTN Src substrate cortactin 0 ;;; 123.86 0.0012399000000000002 1746160.0 2716.83 1830.46 8222.7 12733.2 13062.599999999999 3698.5199999999995 3442.3900000000003 10597.11 4926.61 7215.5 False True 3580.7254264254602 2422.1203984037497 8113.661625383268 9797.757465978932 11249.083466888756 3467.250959726945 3748.7560412069365 8959.570146862297 5187.020546726342 6962.887541227272 0.514258690123024 0.3478614847737192 1.1652725363352863 1.4071399843766526 1.6155773592899367 0.497961648697806 0.5383910078987408 1.28676071440371 0.7449525094314654 1.0 12.765470007042527 -5.258997703201349 24.752346331395803 1.0397856491660658 0.4310600314348754 0.3265678676519599 0.3450438166244305 224.53612784046112 2276179.2565189083 0.09644603224546776 0.2315409767715927 5.508106094005536e-06 5.258997703201349 -0.6087256177311904 HCSQVDSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HCSQVDSVR 9 0 Q14247-3;Q14247;Q14247-2 Q14247-3 CTTN Src substrate cortactin 0 ; 119.68 0.00014615 0.0 1772.5700000000002 606.27 6479.5 2959.7 2928.09 2827.5299999999997 2568.4900000000002 2001.9 2464.5 1235.8 False True 2072.6310911466653 666.4564789011546 6633.99585364059 2793.8776044768656 2354.3517839699384 2679.249349217915 2325.1840329427414 1949.3522461883806 2500.5386501240673 1459.8407574125824 1.4197651905679018 0.4565268338461656 4.544328427573611 1.913823538828116 1.6127456176403683 1.8353024709123815 1.5927655267440888 1.33531841489575 1.712884530334675 1.0 10.511595290054437 -7.010917803035688 1.2949781414913155 1.4001923755139083 2.0749206263638507 0.07866432710940008 0.9790279408571132 1.3627385933480562 4.656229923570612 0.564510120173828 0.40621197321140046 9.75174187087125e-08 7.010917803035688 0.6747282508499424 HCSQVDSVR ddPTM_PC-9_Lapatinib_30min_R1 1 HCSQVDSVR 9 0 Q14247-3;Q14247;Q14247-2 Q14247-3 CTTN Src substrate cortactin 0 114.86 0.0016902000000000002 707100.0 2397.0 1070.6 3213.9 817.73 2728.3 3052.9 2831.1 2822.6 3184.8 2392.6 False True 2362.8183404440356 1068.1210914774674 2949.6655480127656 877.8685920673129 2567.8267580441784 2922.334583657491 2977.680505321312 2953.748300407906 2826.0942865692195 2806.157722060896 0.8420119517404518 0.3806347316404649 1.051140327866701 0.3128365113499712 0.9150685785966147 1.0414006884514218 1.0611237144341432 1.05259525406812 1.0071045773199383 1.0 11.454380383584374 -6.5070229888965425 22.53512027895619 1.0309368835445412 0.6512218302248898 0.4626610176277427 0.19674159904350208 164.30346751240748 233518.19220149957 0.0571591762803935 0.06279448011466035 3.111551626213647e-07 6.5070229888965425 -0.3797150533196514 HCSTTPAGNS(ph)LPEYPK ddPTM_PC-9_AZD4547_30min_R2 1 HCSTTPAGNSLPEYPK 16 0 O94991-2;O94991 O94991-2 SLITRK5 SLIT and NTRK-like protein 5 1 HCSTTPAGNS(0.999)LPEYPK 83.823 0.032234 0.0 0.0 0.0 0.0 661.83 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 509.2553186715698 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HCSTTPAGNS(ph)LPEYPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HCSTTPAGNSLPEYPK 16 0 O94991-2;O94991 O94991-2 SLITRK5 SLIT and NTRK-like protein 5 1 HCSTTPAGNS(1)LPEYPK 84.75299999999999 0.027997 0.0 0.0 1045.7 1193.9 0.0 1698.7 1242.3 1330.4 1339.8 0.0 0.0 True False 0.0 1149.5101852094567 1222.3671038909636 0.0 1365.8519292199824 1177.151601055838 1204.3748807381082 1304.6316696354422 0.0 0.0 0.0 HDADS(ph)FYQFS(ph)CNICGKK ddPTM_PC-9_AZD4547_30min_R2 1 HDADSFYQFSCNICGKK 17 1 A0A0A6YYC7;Q96JP5-2;Q96JP5;H3BTR0 A0A0A6YYC7 ZFP91-CNTF;ZFP91 E3 ubiquitin-protein ligase ZFP91 2 HDADS(0.533)FY(0.47)QFS(0.996)CNICGKK 40.236999999999995 0.040274000000000004 1720000.0 0.0 463.62 0.0 525.19 0.0 397.64 0.0 0.0 0.0 0.0 True False 0.0 613.4760984167616 0.0 404.11555960461436 0.0 372.77550793988485 0.0 0.0 0.0 0.0 0.0 HDDGTQS(ph)DSENAGAHR ddPTM_PC-9_AZD4547_30min_R2 2 HDDGTQSDSENAGAHR 16 0 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 HDDGTQS(1)DSENAGAHR;HDDGTQS(1)DSENAGAHR 258.43 8.392799999999999e-58 7427200.0 11058.8 16151.3 17077.2 12383.3 13108.8 17042.9 15748.9 15744.4 15156.0 12389.1 True False 14575.268362670406 21371.891869114017 16850.745169955735 9528.521505077819 11288.869394358806 15977.204768807616 17150.52159033808 13311.464750319547 15957.115218412766 11955.36137994856 1.2191407603216355 1.7876408073250543 1.409471837314569 0.797008237748378 0.9442516236516624 1.3364050036667618 1.4345464804688217 1.113430562847346 1.334724623646753 1.0 13.545370119233443 -5.5365737706563145 24.98905973106476 1.150623542358329 1.5271822353268818 0.32190884179527324 0.2243774351528009 249.7716527950645 455752.11892932054 0.0629379464837584 0.10907777576465358 2.9068741465212354e-06 5.5365737706563145 0.3765586929685527 HDDGTQS(ph)DSENAGAHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HDDGTQSDSENAGAHR 16 0 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 HDDGTQS(1)DSENAGAHR;HDDGTQS(0.998)DS(0.001)ENAGAHR 207.81 2.3889000000000003e-17 5202000.0 3940.52 8980.7 6528.5 4536.62 6189.56 3871.63 4416.889999999999 2801.7700000000004 4012.2000000000003 3159.2 True False 4607.572207182368 9872.244544621379 6684.164199474126 4282.447889320482 4976.760150128236 3668.5949071849113 3998.490203685614 2728.226506220701 4070.870834663333 3731.9379517865596 1.2346325867975976 2.6453399472773445 1.7910705606116177 1.1475131539286128 1.3335591894677008 0.9830267690888793 1.0714246204901263 0.7310481957275415 1.090819538603132 1.0 11.865709284411784 -5.740197945278343 3.437362861276952 1.0381265519336702 2.0003256621526475 0.5544109773357663 0.3462028229641088 0.15405114601446007 3.794967906636666 0.09472725370144389 0.16490660320102038 1.8188716536968856e-06 5.740197945278343 0.9621991102189773 HDDGTQS(ph)DSENAGAHR ddPTM_PC-9_Lapatinib_30min_R1 2 HDDGTQSDSENAGAHR 16 0 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 HDDGTQS(1)DSENAGAHR;HDDGTQS(1)DSENAGAHR 189.84 1.5969e-08 7606500.0 2236.4 3474.04 6385.6 1969.56 3992.69 3626.3999999999996 4922.0 6317.5 3175.24 3940.6 True False 2204.508525894468 3465.9960738243803 5860.600617128824 2114.408012659553 3757.847824130562 3471.307325551286 5176.83707646904 6611.034113167625 2817.611034440483 4621.727459480555 0.47698799750131465 0.7499351928929904 1.2680541352794326 0.4574930112597327 0.8130829559025781 0.751084384785734 1.1201086870342793 1.430424916035757 0.6096445666999931 1.0 12.174216472107442 -7.257995597512124 24.347213787890347 1.0759132937063214 0.765385365527139 0.1966542834963838 0.28002964366358335 329.07210124984755 2326522.792422485 0.10866666616827476 0.08065792440004854 5.5208303577496424e-08 7.257995597512124 -0.3105279281791824 HDDGTQS(ph)DSENAGAHRR ddPTM_PC-9_AZD4547_30min_R2 1 HDDGTQSDSENAGAHRR 17 1 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 HDDGT(0.034)QS(0.709)DS(0.256)ENAGAHRR 67.214 0.008748299999999999 601060.0 383.24 576.58 995.02 654.96 868.55 616.88 441.03 637.98 533.79 603.75 True False 505.1023481127981 762.9482093635661 981.8253846654819 503.96909103112813 747.9668247643062 578.3063960817731 480.2808156116806 539.3948503219469 562.005049646117 582.6128962671977 0.8669604661156493 1.309528529580751 1.685210524785908 0.8650153373879284 1.2838143981304424 0.9926082992446333 0.8243566503399444 0.9258203067214116 0.9646285779921535 1.0 9.1863938259849 -6.880333377033842 4.83450069486479 0.9207957524288298 1.2155449830617853 0.2560514458286184 0.22290996802934956 0.2928984561944891 11.138789095125318 0.08126446973820393 0.07161940489002028 1.317245194764485e-07 6.880333377033842 0.29474923063295544 HDDGTQSDSENAGAHRR ddPTM_PC-9_AZD4547_30min_R2 1 HDDGTQSDSENAGAHRR 17 1 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 0 38.948 0.03422 397250.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 False True 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HDDYYR ddPTM_PC-9_AZD4547_30min_R2 3 HDDYYR 6 0 F8WJN3;Q16630-3;Q16630;Q16630-2 F8WJN3 CPSF6 Cleavage and polyadenylation specificity factor subunit 6 0 ;; 132.8 0.005645300000000001 6673200.0 8850.3 7872.5 12969.3 14959.3 12650.400000000001 9577.5 8999.6 13784.8 10322.2 9382.900000000001 False True 11664.511302324121 10417.13166987178 12797.318608009911 11510.664503881078 10894.11032179884 8978.617410960287 9800.546965464675 11654.675903191279 10867.810418811041 9054.407526932488 1.2882688643765852 1.1505039549949398 1.4133800107786259 1.2712774932697046 1.2031831226277507 0.9916294781578185 1.0824062133621424 1.287182608969637 1.2002784706215792 1.0 13.14440452650885 -6.524237914026975 24.996417734396207 1.1249384222452947 1.2755397357910392 0.379762630153177 0.10099666184999391 56.7445058595999 1043550.0382816681 0.03490189248626564 0.03515715539041338 2.9906258712112263e-07 6.524237914026975 0.15060131354574446 HDDYYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HDDYYR 6 0 F8WJN3;Q16630-3;Q16630;Q16630-2 F8WJN3 CPSF6 Cleavage and polyadenylation specificity factor subunit 6 0 ;; 159.65 0.00013314 4420200.0 10024.2 14595.2 20638.6 13873.699999999999 19232.1 12814.800000000001 12101.3 12058.0 10694.5 8907.0 False True 11721.099073025267 16044.114999683528 21130.702496326365 13096.401568142277 15463.70806378502 12142.769328833905 10954.977258175033 11741.490276507058 10850.886830493746 10521.7685922268 1.1139856356168583 1.5248496352159362 2.0082842833035848 1.2446958373345662 1.469687147007699 1.1540616220931392 1.0411726091627103 1.1159236371327683 1.0312797449765327 1.0 13.36108960554661 -6.765648259677023 1.6579905812263844 1.0479079408551863 1.517937751628708 0.45709171156492623 0.22034544039903106 0.3431348597097306 1.9545553630914623 0.09754118135390427 0.08852759943802968 1.715346024434257e-07 6.765648259677023 0.4700298107735217 HDDYYR ddPTM_PC-9_Lapatinib_30min_R1 4 HDDYYR 6 0 F8WJN3;Q16630-3;Q16630;Q16630-2 F8WJN3 CPSF6 Cleavage and polyadenylation specificity factor subunit 6 0 ;;; 142.63 1.4859999999999998e-11 6677800.0 15266.7 12081.800000000001 16752.7 12275.7 17660.5 15212.3 12274.81 17396.1 17637.1 13843.5 False True 15048.99405843011 12053.825334403577 15375.357673292094 13178.495928534741 16621.74411187891 14561.705390603305 12910.339600693405 18204.386313585335 15650.62407110335 16236.330529695739 0.9268716247742045 0.7423983708854355 0.9469724483109683 0.811667137745914 1.0237377270361836 0.8968593835885764 0.795151316800357 1.1212130893917245 0.9639261803939535 1.0 13.98693799453627 -7.250883920941524 0.539958474764134 1.023529386104615 0.8501575056598044 0.22158992568012859 0.09651568484565147 1.2875528809964587 0.7927426507165667 0.08946826867701807 0.0748192549720248 5.611979540492255e-08 7.250883920941524 -0.17337188044481067 HDGGS(ph)PSIK ddPTM_PC-9_AZD4547_30min_R2 3 HDGGSPSIK 9 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 HDGGS(1)PSIK;HDGGS(0.999)PS(0.001)IK;HDGGS(0.98)PS(0.02)IK 82.494 0.012831 38183000.0 176686.0 142035.0 222842.0 311368.0 275117.0 259942.0 211086.0 231570.0 222451.0 284009.0 True False 232868.47270289616 187945.03610419028 219886.96947762373 239586.9181876454 236921.75341509617 243687.78564759422 229872.245072234 195786.17744922003 234209.3057172827 274065.93135561125 0.8496804821783567 0.6857657760472398 0.8023141307275868 0.8741944575255216 0.8644699187644777 0.8891575265931168 0.8387479754788121 0.7143761958328918 0.854572856096393 1.0 18.064163474913165 -12.31385263358259 1.4397347947232018 3.514728976374692 0.8173185533164427 0.4135886631745316 0.06453012277977781 745824.2198956488 23404.81316280014 6110537.394399795 0.019226141535682563 4.854531980006585e-13 12.31385263358259 -2.6974104230582494 HDGGS(ph)PSIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HDGGSPSIK 9 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 HDGGS(0.994)PS(0.006)IK;HDGGS(0.991)PS(0.009)IK;HDGGS(0.972)PS(0.028)IK 74.237 0.015711000000000003 26196400.0 163746.0 174650.0 198184.0 221165.0 250026.0 249911.0 219085.0 224781.0 219881.0 185681.0 True False 191464.96366908008 191988.09777836085 202909.4581770055 208773.84207660452 201035.20012665822 236805.2272168284 198331.68276195752 218880.73692515632 223096.34365101674 219343.49545001256 0.8729001207729642 0.8752851201922881 0.9250762497456766 0.9518123236263606 0.9165313961747877 1.079609070380641 0.9042059002253681 0.9978902564495618 1.017109457443927 1.0 17.742832398842054 -5.5627638580604275 0.6713034164158348 0.9953920506554915 0.841293111908545 0.506379542405121 0.045151832902223514 1.1868916892145898 0.7822615568000293 0.02327168485952072 0.12154964146771947 2.736756397285832e-06 5.5627638580604275 -0.15409893874694647 HDGGS(ph)PSIK ddPTM_PC-9_Lapatinib_30min_R1 3 HDGGSPSIK 9 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 HDGGS(0.998)PS(0.002)IK;HDGGS(0.995)PS(0.005)IK;HDGGS(0.989)PS(0.011)IK 73.9 0.016065 22638200.0 209484.0 202831.0 210764.0 182113.0 231048.0 196389.0 174932.0 195258.0 230435.0 163278.0 True False 206496.71974533924 202361.35728139905 193435.79749256757 195506.1975311588 217458.2108978455 187989.90027511882 183989.1230111501 204330.39950437407 204480.9837118747 191500.3847457411 1.0783096860066839 1.0567151473354912 1.0101065736729258 1.0209180404036071 1.1355497336810532 0.9816685252341232 0.9607767799288558 1.066997331497102 1.0677836704263974 1.0 17.546987765126026 HDLDLICR ddPTM_PC-9_AZD4547_30min_R2 2 HDLDLICR 8 0 P62136-3;P62136;P62136-2;E9PMD7;F8VR82;F8VYE8;F8W0W8;P36873;P36873-2;P62140 P62136-3;P62140 PPP1CA;PPP1CC;PPP1CB Serine/threonine-protein phosphatase PP1-alpha catalytic subunit;Serine/threonine-protein phosphatase;Serine/threonine-protein phosphatase PP1-gamma catalytic subunit;Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0 ; 162.25 1.9366e-05 18886100.0 106592.0 122544.0 135706.0 146199.0 138268.0 154475.0 135496.0 166319.0 145737.0 147925.0 False True 140486.0387486677 162153.95152146928 133906.44977127493 112495.07930203369 119071.87487940927 144815.6538301322 147554.88150946717 140618.220180407 153440.36029201758 142746.190774866 0.9841666386056989 1.1359599204802073 0.938073717024556 0.7880776270902861 0.8341509796727606 1.0144975010823938 1.0336869986407222 0.9850926278108874 1.0749173722892404 1.0 17.123092721786506 -6.9605591554193404 24.97450308051548 1.022455065049346 0.9376022597313555 0.18778847790307018 0.0890800987993273 318.5781118343692 201727.3147748185 0.035884301774632754 0.0316469369830295 1.0950673856556247e-07 6.9605591554193404 -0.08485280531799055 HDLDLICR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HDLDLICR 8 0 P62136-3;P62136;P62136-2;E9PMD7;F8VR82;F8VYE8;F8W0W8;P36873;P36873-2;P62140 P62136-3;P62140 PPP1CA;PPP1CC;PPP1CB Serine/threonine-protein phosphatase PP1-alpha catalytic subunit;Serine/threonine-protein phosphatase;Serine/threonine-protein phosphatase PP1-gamma catalytic subunit;Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0 ;; 124.08 0.0027843000000000004 14187500.0 121584.0 152432.0 148394.0 140468.0 151644.0 103953.0 130935.0 118256.0 104027.0 89313.0 False True 142165.76980653824 167564.44157200714 151932.27574737903 132598.03336340073 121930.44678556251 98501.5216812023 118531.8889126913 115151.90530258926 105548.19807525113 105504.73989868077 1.347482302151203 1.588217190364377 1.4400516592267225 1.2567969315003138 1.1556869094474411 0.9336217669063602 1.123474537983041 1.0914382179717512 1.0004119073381168 1.0 16.68694828924332 -6.056957013943625 1.7365208915240067 1.0433419171701577 1.48009224105937 0.8493482038016724 0.07794906569180013 0.12609416363884446 0.7606281500439337 0.02583700692306834 0.04068336089231676 8.770876301501212e-07 6.056957013943625 0.4367503238892123 HDLDLICR ddPTM_PC-9_Lapatinib_30min_R1 2 HDLDLICR 8 0 P62136-3;P62136;P62136-2;E9PMD7;F8VR82;F8VYE8;F8W0W8;P36873;P36873-2;P62140 P62136-3;P62140 PPP1CA;PPP1CC;PPP1CB Serine/threonine-protein phosphatase PP1-alpha catalytic subunit;Serine/threonine-protein phosphatase;Serine/threonine-protein phosphatase PP1-gamma catalytic subunit;Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0 ; 101.25 0.0038966 12187000.0 40476.0 81403.0 86686.0 81613.0 109340.0 98038.0 100663.0 96550.0 88369.0 87076.0 False True 39898.80481761065 81214.51635488549 79559.01169763674 87615.09227298688 102908.83617071086 93845.14327774018 105874.83759215818 101036.06547310401 78415.95265317617 102126.97057852327 0.39067843285269394 0.7952308376017222 0.779020578471634 0.8579035662829291 1.0076558189061962 0.9189065605895421 1.0366981120893355 0.9893181487785297 0.7678280498184737 1.0 16.640004390422803 -4.56601231647006 0.9731344252075557 0.9473315154063399 5.534388602046092e-19 0.7785605641704352 0.0857439920363283 1.319498996283534 0.7557625106445045 0.028194714336337596 1.450390927483612 2.7163622324734196e-05 4.56601231647006 -0.9473315154063399 down HDNFPHNQR ddPTM_PC-9_AZD4547_30min_R2 1 HDNFPHNQR 9 0 Q9NRI2;C4P0D4;Q5VVQ1;C4P0D6;C4P0D8;Q99598 Q9NRI2 TRAX;DISC1;TSNAX Translin-associated protein X 0 74.173 0.024211 0.0 0.0 582.09 955.77 2089.4 2861.1 1122.0 613.29 1159.1 847.31 1176.0 False True 0.0 770.2392091096438 943.0958653109755 1607.7211109082075 2463.885651180886 1051.8411626308996 667.8716218998433 979.9877284682412 892.0970767823513 1134.8285979465409 0.0 0.6787273518691568 0.8310469678130217 1.4167083150859612 2.171152238883703 0.9268722735170702 0.5885220227163372 0.8635557213146704 0.7861073279229926 1.0 10.148258697098129 -4.985321539238255 1.9745512528906457 1.105336559988889 4.150420838929127e-15 0.380441888263504 0.4210666979337438 0.612011706812721 3.5380741068085344 0.13007222160036858 1.0692271325523661 1.0343760606019168e-05 4.985321539238255 -1.1053365599888847 HDS(ph)PDLAPNVTYSLPR ddPTM_PC-9_AZD4547_30min_R2 2 HDSPDLAPNVTYSLPR 16 0 Q9BRD0;H7C462 Q9BRD0 BUD13 BUD13 homolog 1 HDS(1)PDLAPNVTYSLPR;HDS(1)PDLAPNVTYSLPR 182.91 4.4353e-07 34777000.0 18526.9 13511.7 23937.1 34239.2 29309.0 28658.0 23831.3 30387.3 20439.7 27241.3 True False 24418.068816540545 17879.092789305374 23619.678413776695 26345.881430366753 25239.951260165868 26866.010729658025 25952.239532654567 25691.641015687164 21520.100813525416 26287.590378606412 0.9288819730093125 0.6801343345587083 0.8985105927776119 1.0022174360951615 0.9601470084038916 1.0220035515892072 0.9872429978890433 0.977329631421667 0.8186410585216318 1.0 14.682094284603247 -5.5078033481526605 9.852376388123025 0.9673745552555528 0.8005963383757215 0.4155065812087796 0.07674603996531178 0.26398864471970335 162.00968318427002 0.019469675238730014 0.03771071435616389 3.105965674661687e-06 5.5078033481526605 -0.1667782168798313 HDS(ph)PDLAPNVTYSLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 HDSPDLAPNVTYSLPR 16 0 Q9BRD0;H7C462 Q9BRD0 BUD13 BUD13 homolog 1 HDS(1)PDLAPNVTYSLPR;HDS(1)PDLAPNVTYSLPR;HDS(1)PDLAPNVTYSLPR;HDS(1)PDLAPNVTYSLPR;HDS(1)PDLAPNVTYSLPR 105.95 0.00060898 48658200.0 68939.9 81245.6 79915.0 95802.9 95013.2 76048.20000000001 90084.0 75890.5 77396.70000000001 62571.0 True False 80610.06344490864 89311.12623453508 81820.47667932525 90435.3741101926 76396.04551796312 72060.09851679513 81550.59136831906 73898.45478763139 78528.48031732904 73914.62698823646 1.0905833761122512 1.2083011154037073 1.106959204331059 1.2235112019788104 1.033571413816667 0.974909858210656 1.1033078930547517 0.999781204326342 1.0624213841981085 1.0 16.17357226753773 -6.284935760992751 22.711024589121173 1.0299986564739079 1.1573803378033005 0.6101280121779451 0.050255721283376895 156.44517664088562 151215.30326450814 0.014522746516528429 0.016482434184910414 5.188767833173451e-07 6.284935760992751 0.12738168132939265 HDS(ph)PDLAPNVTYSLPR ddPTM_PC-9_Lapatinib_30min_R1 1 HDSPDLAPNVTYSLPR 16 0 Q9BRD0;H7C462 Q9BRD0 BUD13 BUD13 homolog 1 HDS(1)PDLAPNVTYSLPR 86.772 0.004404 3463000.0 5446.4 5233.7 2537.6 5085.4 6906.4 7465.6 5850.8 5092.5 5593.1 5120.1 True False 5368.733337252562 5221.581689207567 2328.968323419271 5459.397280397091 6500.179130504831 7146.313691163601 6153.725795815735 5329.116141085259 4963.1461800459365 6005.102462895595 0.894028598250398 0.8695241624053451 0.38783157120291134 0.9091264160985905 1.08244266782594 1.1900402591495045 1.024749508245439 0.8874313425978776 0.8264881757992122 1.0 12.551973146987704 -5.988191118265051 24.998220133221825 1.005783943481996 0.7183862236261996 0.39391454803782466 0.15790304161643737 237.77665276995592 503344.7701892271 0.04707203239462508 0.06976377474922336 1.0275640025634738e-06 5.988191118265051 -0.2873977198557963 HDS(ph)PEDVK ddPTM_PC-9_AZD4547_30min_R2 4 HDSPEDVK 8 0 P31948-2;P31948;P31948-3;H0YGI8 P31948-2 STIP1 Stress-induced-phosphoprotein 1 1 HDS(1)PEDVK;HDS(1)PEDVK;HDS(1)PEDVK;HDS(1)PEDVK 128.91 0.0021195999999999997 111755000.0 1011227.0 933997.0 929996.0 1072123.0 1044527.0 1211068.0 1014598.0 966478.0 1072683.0 1086012.0 True False 1332776.1511717464 1235893.2649431874 917663.6453914089 824961.6064852299 899512.4558984343 1135339.7265107664 1104895.2564632362 817131.0325550253 1129382.8334542534 1047991.0504363286 1.2717438289352263 1.179297537348841 0.8756407270933677 0.7871838277070773 0.8583207418841262 1.0833486851229028 1.0542983702038444 0.7797118422097352 1.0776645783225318 1.0 19.99919496602181 -5.1426199525591985 4.271638100530524 0.9329867724056552 1.2507162206043494 0.5308656520527382 0.10855017860452619 0.1729310327059947 5.118544940916624 0.029187725998079967 0.08743843361424002 7.200788372927881e-06 5.1426199525591985 0.3177294481986942 HDS(ph)PEDVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HDSPEDVK 8 0 P31948-2;P31948;P31948-3;H0YGI8 P31948-2 STIP1 Stress-induced-phosphoprotein 1 1 HDS(1)PEDVK;HDS(1)PEDVK;HDS(1)PEDVK;HDS(1)PEDVK 98.943 0.0030328000000000004 67248000.0 578999.0 692329.0 521677.0 716877.0 708111.0 582945.0 670113.0 591469.0 581675.0 509669.0 True False 677012.0949484796 761058.8476770384 534115.7581510391 676712.7058365932 569361.7327673446 552374.337983978 606635.0454420148 575943.5654632082 590180.8964540148 602067.9551624155 1.1244778752023878 1.264074663252478 0.8871353367527335 1.1239806072290317 0.9456768590411891 0.9174617802652658 1.0075856724152796 0.9566089019101508 0.9802562840183148 1.0 19.199566807007876 -5.257894797111832 24.99953395845294 0.9788367901038013 1.1942762772739375 0.6214522588048061 0.0677174146418187 179.64566261725764 1267005.8156803912 0.016576225752056355 0.04039682364159194 5.522111899469973e-06 5.257894797111832 0.21543948717013617 HDS(ph)PEDVK ddPTM_PC-9_Lapatinib_30min_R1 3 HDSPEDVK 8 0 P31948-2;P31948;P31948-3;H0YGI8 P31948-2 STIP1 Stress-induced-phosphoprotein 1 1 HDS(1)PEDVK;HDS(1)PEDVK;HDS(1)PEDVK 105.17 0.0021799 124851000.0 536650.0 721420.0 648590.0 682870.0 787400.0 708850.0 690180.0 726300.0 690890.0 601990.0 True False 528997.2725904437 719749.5963139143 595265.433829803 733090.5377875419 741086.680087963 678534.137910057 725914.1433233244 760046.549488508 613074.6928057679 706043.1693987444 0.7492421080157602 1.0194130153923053 0.8431006199475338 1.038308377675873 1.0496336657701273 0.9610377485669699 1.028144134503138 1.0764873628559457 0.8683246568731101 1.0 19.42939687092683 -4.232809391079119 1.738139958096816 0.9928656916580884 6.402668084305918e-38 0.4611040180849998 0.07482211442088334 5.1071059123913916 4.006285789501157 0.01979037479166178 13.570673425286808 5.850468009023234e-05 4.232809391079119 -0.9928656916580884 HDS(ph)PEDVKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HDSPEDVKR 9 1 P31948-2;P31948;P31948-3;H0YGI8 P31948-2 STIP1 Stress-induced-phosphoprotein 1 1 HDS(1)PEDVKR 55.258 0.042025 11681000.0 60909.0 67728.0 66568.0 87042.0 75151.0 53517.0 83682.0 66683.0 59461.0 53819.0 True False 71219.69069241386 74451.5882412415 68155.23358054587 82165.31893397128 60425.70102596742 50710.474308705845 75755.03515478545 64932.6419064788 60330.50463583979 63575.9586690304 1.1202299136875924 1.1710651290187923 1.0720284051925144 1.2923960669113161 0.9504489163983687 0.7976360147819259 1.1915673273470875 1.0213395639774958 0.9489515517951355 1.0 15.956193691189617 -6.284155223408759 24.946441799005573 0.9870186413493323 1.1578751627837471 0.4131850107845384 0.10435302137719991 832.9946531696116 914788.8058631915 0.03309178393890442 0.037547228182549984 5.198101753183601e-07 6.284155223408759 0.17085652143441488 HDS(ph)VDSGVSK ddPTM_PC-9_AZD4547_30min_R2 2 HDSVDSGVSK 10 0 Q9HC44 Q9HC44 GPBP1L1 Vasculin-like protein 1 1 HDS(0.999)VDS(0.001)GVSK;HDS(1)VDSGVSK 95.094 0.006049499999999999 13642900.0 42357.0 46829.0 59048.0 95630.0 76506.0 63374.0 67860.0 90303.0 80993.0 81343.0 True False 55825.64491966858 61965.558458993444 58264.98493872221 73583.98096877188 65884.46248968747 59411.213761649386 73899.40853776086 76348.74630650313 85274.12462951333 78495.20632888211 0.7111981422886926 0.7894183779754379 0.7422744351368596 0.9374327988956039 0.839343771053258 0.7568769679096847 0.9414512298768206 0.9726548903714495 1.0863609208469198 1.0 16.26031693142992 -7.556137818825748 2.0193134259761423 1.0330561853727696 0.8009944075398058 0.7125989748959345 0.06457061940439916 0.19346496123700574 1.561489178861885 0.040927481176321986 0.02038509757458904 2.778831294685766e-08 7.556137818825748 -0.23206177783296378 HDS(ph)VDSGVSK ddPTM_PC-9_Lapatinib_30min_R1 1 HDSVDSGVSK 10 0 Q9HC44 Q9HC44 GPBP1L1 Vasculin-like protein 1 1 HDS(0.999)VDS(0.001)GVSK 89.301 0.009437000000000001 7509100.0 21213.0 22079.0 25063.0 19423.0 29331.0 27727.0 27698.0 23089.0 22591.0 26882.0 True False 20910.498730012238 22027.877432029713 23002.41688597777 20851.432213228592 27605.808246964716 26541.180844793893 29132.06691264513 24161.799230538538 20046.563686223704 31528.517881986572 0.6632249193660699 0.6986651740015685 0.7295749509088062 0.661351487922044 0.87558217453466 0.8418150496049124 0.9239910046418444 0.7663474483950634 0.6358232176107796 1.0 14.944369731791904 -6.258484399379732 24.794867888120017 0.833141510687245 0.6919064046127155 0.39551238730491045 0.09197207149270376 272.30741986150827 2284893.2307545342 0.028037995357541572 0.034609614738737346 5.514620115095911e-07 6.258484399379732 -0.1412351060745295 HDT(ph)PDS(ph)SPRR ddPTM_PC-9_AZD4547_30min_R2 1 HDTPDSSPRR 10 1 Q9BRD0;Q9BRD0-2 Q9BRD0 BUD13 BUD13 homolog 2 HDT(0.998)PDS(0.598)S(0.404)PRR 72.958 0.034132 0.0 4255.4 5083.9 3702.8 4284.0 4731.9 4307.3 5104.6 5138.0 5228.1 3481.9 True False 5608.5286821814 6727.171253916947 3653.6984526334586 3296.3899871402136 4074.9573635394863 4037.963850089193 5558.89951107949 4344.040159494285 5504.446692622314 3359.9997408078752 1.669205093698278 2.002134456206676 1.0874103376433495 0.9810685242337646 1.2127850231797064 1.2017750480892324 1.6544345059213945 1.2928691948201783 1.6382283087018423 1.0 11.714245406375882 -5.260474233831314 24.99755722311273 1.2695944650020938 1.8356697966090232 0.49765817135114576 0.23171141800461337 70.90703862300886 1836446.8460921515 0.06230483980762058 0.14668570553584845 5.489411226567918e-06 5.260474233831314 0.5660753316069294 HDTPDS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 HDTPDSSPR 9 0 Q9BRD0;Q9BRD0-2 Q9BRD0 BUD13 BUD13 homolog 1 HDT(0.004)PDS(0.603)S(0.393)PR 115.78 0.0019581 2290200.0 11352.0 8747.2 23605.0 37285.0 31828.0 30216.0 18466.0 29539.0 26092.0 30630.0 True False 14961.699863731565 11574.561339181011 23291.982276766983 28689.519297507664 27409.231591270924 28326.58874336475 20109.438226617924 24974.426288692423 27471.16985212625 29557.653023046394 0.5061870051747944 0.3915927063003348 0.7880186650342635 0.9706291387593651 0.9273142075894752 0.958350404928234 0.6803462443698894 0.8449394229379313 0.9294097143202374 1.0 14.851244098748085 -5.368226311463656 4.099141163336906 0.8886424914173724 0.4492693410896287 0.7953755805369038 0.09010219040430396 0.09641717015572168 2.7693074205900436 0.02500853901623576 0.05629157613985609 4.283252613377404e-06 5.368226311463656 -0.4393731503277437 HDTPDS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HDTPDSSPR 9 0 Q9BRD0;Q9BRD0-2 Q9BRD0 BUD13 BUD13 homolog 1 HDTPDS(0.5)S(0.5)PR 112.64 0.0012209000000000002 1477300.0 2617.6 4508.2 10074.0 9489.9 16496.0 21450.0 13068.0 18637.0 19789.0 14409.0 True False 3060.707980043387 4955.744302344146 10314.20236585775 8958.211669670918 13263.727217526834 20325.124239433095 11830.104435873114 18147.798497533764 20078.37668789011 17021.237638418756 0.17981700538244302 0.29115064413168756 0.6059607758825651 0.5262961401497195 0.7792457575228949 1.1941037820632452 0.6950202263301525 1.0661856019548333 1.1796073302314436 1.0 14.055048320797367 -5.644305771325776 0.5811508842621782 1.0673313136316895 7.460017689815636e-18 0.8101283631962217 0.14805979919797482 0.7003299673742995 0.35014459438322926 0.09401560495782561 0.4478574810908317 2.268267283091266e-06 5.644305771325776 -1.0673313136316895 down HDTPDS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 2 HDTPDSSPR 9 0 Q9BRD0;Q9BRD0-2 Q9BRD0 BUD13 BUD13 homolog 1 HDT(0.009)PDS(0.496)S(0.496)PR;HDT(0.007)PDS(0.497)S(0.497)PR 107.79 0.002479 2779700.0 12784.599999999999 11824.0 22846.1 15336.7 28967.0 28375.0 22806.4 31106.0 44193.0 22963.5 True False 12602.289259591493 11796.622254464393 20967.78184649629 16464.6120797314 27263.218011313173 27161.467395355674 23987.203799427774 32551.298318035948 39215.518967079115 26932.71037805962 0.46791760215331996 0.4380035313517632 0.7785247586361534 0.6113239940805988 1.012271606853308 1.00849365006659 0.890634602411521 1.2086157635494954 1.4560554217010973 1.0 14.717071802564847 -6.107633753531609 0.5649793798185742 1.2154156426482488 0.3547950337836783 0.7522121537510441 0.15225066280467558 0.5882054306448816 0.36036623987835253 0.11164593353156167 0.2788404932079156 7.804880292837022e-07 6.107633753531609 -0.8606206088645705 down HDTPDSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 HDTPDSSPR 9 0 Q9BRD0;Q9BRD0-2 Q9BRD0 BUD13 BUD13 homolog 1 HDT(0.001)PDS(0.16)S(0.839)PR 80.706 0.018298 1344500.0 7851.1 6037.0 17412.0 27646.0 20218.0 17781.0 13752.0 21616.0 16631.0 20878.0 True False 10347.586486975235 7988.3421900306075 17181.105503201303 21272.641826442177 17411.079688083297 16669.151259126582 14975.901358845971 18275.743886264794 17510.08070714057 20147.06757476862 0.5136026098375794 0.39650148391991735 0.8527844282767102 1.0558678947939393 0.8641992003783338 0.8273735717252649 0.7433290876336361 0.9071168207701157 0.8691131174379687 1.0 14.298282247920172 -5.285793854811665 8.046478583143918 0.8846392741279901 0.45484880673872186 0.801610920134626 0.08652093100436137 0.08994265191324553 26.65341541001786 0.023433169523794185 0.050641248718153134 5.178525810685012e-06 5.285793854811665 -0.4297904673892683 HDTPDSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HDTPDSSPR 9 0 Q9BRD0;Q9BRD0-2 Q9BRD0 BUD13 BUD13 homolog 1 HDT(0.017)PDS(0.142)S(0.841)PR 92.538 0.0069509 887920.0 6749.7 6585.4 11925.0 16837.0 17879.0 20946.0 20166.0 15264.0 18961.0 15598.0 True False 7892.2908973482845 7239.154990607597 12209.337225814343 15893.677476290506 14375.738295475387 19847.55488667438 18255.730490803282 14863.336173544843 19238.268754312216 18425.793926299928 0.42832840359097246 0.392881577833932 0.6626220435683605 0.8625776202568279 0.7801964112361138 1.0771614491110264 0.9907703604969821 0.8066591992179921 1.044094427152613 1.0 14.16943916271561 -5.56562127963414 1.1688413424697925 0.9589561891775805 0.3502517490580815 0.8556959331538925 0.08825008743538611 0.21067634357869292 0.5150369776686584 0.030438009540389343 0.11248706835608531 2.7188091344707805e-06 5.56562127963414 -0.608704440119499 down HDTPDSS(ph)PRR ddPTM_PC-9_AZD4547_30min_R2 1 HDTPDSSPRR 10 1 Q9BRD0;Q9BRD0-2 Q9BRD0 BUD13 BUD13 homolog 1 HDT(0.002)PDS(0.282)S(0.715)PRR 60.161 0.03182 2432400.0 13527.0 13229.0 23644.0 32164.0 26604.0 27555.0 19609.0 26607.0 25145.0 23198.0 True False 17828.30462092113 17505.015542805188 23330.465111284844 24749.08672884636 22910.49381846711 25831.981494023556 21354.163012333513 22495.49951803511 26474.11336546507 22385.845080921656 0.7964097203600908 0.781968046304575 1.0421972021582622 1.1055685697538744 1.0234366286217438 1.153942654415976 0.9539136420868295 1.0048983827377107 1.1826273821589002 1.0 14.450299161540821 -5.275397981441637 6.086573167139478 1.0592964090835684 0.7875882072591553 0.7184418489178246 0.06742398353821157 0.07223752425737326 11.742191663090022 0.01720441576576006 0.039465915735015664 5.3039817192774065e-06 5.275397981441637 -0.271708201824413 HDTPDSS(ph)PRR ddPTM_PC-9_Lapatinib_30min_R1 1 HDTPDSSPRR 10 1 Q9BRD0;Q9BRD0-2 Q9BRD0 BUD13 BUD13 homolog 1 HDT(0.001)PDS(0.203)S(0.795)PRR 61.03 0.030088999999999998 1515800.0 11487.0 13314.0 16749.0 12791.0 16904.0 16734.0 13121.0 14282.0 23144.0 14480.0 True False 11323.193273542196 13283.17225100972 15371.961873009677 13731.692809525148 15909.739954542689 16018.32582885926 13800.34117845393 14945.59385900436 20537.279002875548 16982.8487066128 0.6667428691826689 0.7821521866256457 0.9051462530561275 0.8085623941393464 0.9368122056194105 0.9432060607489265 0.8126046116798025 0.8800404524115456 1.2092952930139877 1.0 14.05179085670856 -2.9617984902455134 0.22473138175837784 1.0380458193841617 2.648312166763534e-14 0.5208470661274426 0.09623912259558028 24.343604042149217 0.5493628499374186 0.1555274222108909 8.075692230528142 0.0010919468750203618 2.9617984902455134 -1.0380458193841353 HDWDYCEHR ddPTM_PC-9_AZD4547_30min_R2 2 HDWDYCEHR 9 0 P17568 P17568 NDUFB7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 0 ; 89.029 0.0040641 17232600.0 26166.0 19715.5 35390.0 30139.0 30748.0 24585.0 26642.0 28068.0 27278.0 29297.0 False True 34486.243713389704 26088.1498173842 34920.705476584786 23190.919192908237 26479.170949113926 23047.69606353001 29013.08638760719 23730.735538475208 28719.859390859267 28271.320947312786 1.2198313541011834 0.9227778873864011 1.2351989332816806 0.8202983948336717 0.9366089047788478 0.8152323729931945 1.026237381750813 0.8393925272434373 1.0158654929630768 1.0 14.787051672680168 -5.767750219289562 24.999968679226416 0.9157656869951237 1.1056202449957497 0.42106895079795603 0.10866180183504484 138.44564563158846 548445.2588424705 0.02810526438864387 0.04287025863721941 1.707063909744641e-06 5.767750219289562 0.189854558000626 HDWDYCEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HDWDYCEHR 9 0 P17568 P17568 NDUFB7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 0 ; 113.18 0.00089123 12191300.0 29071.0 27195.0 28336.0 24863.0 36869.0 25876.0 30295.0 25374.0 23735.7 24274.0 False True 33992.14612157752 29894.73987450625 29011.637704878423 23470.00671693359 29644.784116331026 24519.01700790539 27425.23828319377 24707.9593859753 24082.78970896728 28674.68404712171 1.185440999653824 1.0425481872923026 1.0117509109151122 0.8184922518541036 1.0338312383011834 0.8550754026657372 0.956426869015376 0.8616645730210032 0.8398624260128386 1.0 14.80748996949894 -4.7363469519568655 1.0271346150644742 0.9064555838645133 1.346001868887804 0.5959752815111978 0.07035522568190539 1.3201875820587166 1.0565573179349306 0.021849986073405884 0.6555129985594403 1.835071743736917e-05 4.7363469519568655 0.43954628502329063 HDWDYCEHR ddPTM_PC-9_Lapatinib_30min_R1 2 HDWDYCEHR 9 0 P17568 P17568 NDUFB7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 0 ; 108.57 0.0010208 7098700.0 50771.0 48763.0 25353.0 15353.9 22907.0 22539.0 17315.8 13450.3 31896.0 12426.1 False True 50046.99622973887 48650.092269489796 23268.574205410136 16483.077025108927 21559.655296894784 21575.0595109752 18212.327397139903 14075.250040734236 28303.536600229774 14573.934828262523 3.434007138050677 3.338157665913603 1.5965883256378037 1.1309970312989253 1.479329745257622 1.4803867154075463 1.2496506682479205 0.9657824195452547 1.9420655391804074 1.0 13.831102823926207 -5.284591699869772 3.8792484550703783 1.332153422561733 3.439789504515972 0.9032802028753162 0.26706289780838044 0.053576349647028454 1.8208293242092752 0.06748947466592735 0.17030349569351783 5.192880159519704e-06 5.284591699869772 2.107636081954239 HEAFESDLAAHQDR ddPTM_PC-9_AZD4547_30min_R2 2 HEAFESDLAAHQDR 14 0 O43707;O43707-2;P12814-4;P12814-3;P12814;P12814-2;H9KV75;P35609-2;P35609;A0A494C1A0;H7C5W8;Q08043;A0A087WSZ2;A0A494C060;F6THM6 O43707;P12814-4 ACTN4;ACTN1;ACTN2;ACTN3 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2;Alpha-actinin-3 0 ; 203.87 4.8984e-11 10917900.0 33181.3 36187.0 65965.0 77096.0 76710.0 80752.0 59709.0 92998.0 68626.0 62810.0 False True 43732.26318608491 47883.740074645946 65090.260999234604 59322.708321326325 66060.14061098367 75702.56467448336 65022.98532834018 78627.29598144206 72253.43025724424 60611.041017876065 0.721523050118656 0.7900167901838802 1.0739010567404292 0.9787442572357441 1.089902755365982 1.2489896791602102 1.0727910993834093 1.2972437803576489 1.192083637631871 1.0 15.887293001149267 -4.946630069366888 0.6920199393293851 1.1756299796607874 0.46772652136683196 0.7182835462698896 0.09292891783378553 1.2701872523012028 0.5356588221013958 0.04049080894758044 0.6822260374333011 1.1307586811562587e-05 4.946630069366888 -0.7079034582939554 HEAFESDLAAHQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HEAFESDLAAHQDR 14 0 O43707;O43707-2;P12814-4;P12814-3;P12814;P12814-2;H9KV75;P35609-2;P35609;A0A494C1A0;H7C5W8;Q08043;A0A087WSZ2;A0A494C060;F6THM6 O43707;P12814-4 ACTN4;ACTN1;ACTN2;ACTN3 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2;Alpha-actinin-3 0 109.95 0.00022751 4259600.0 5891.3 10155.0 14334.0 13450.0 13285.0 9574.9 13864.0 12209.0 10552.0 8264.5 False True 6888.580731521096 11163.12128794305 14675.776921997725 12696.440105488338 10681.899617170453 9072.775388351882 12550.701553332181 11888.526686504785 10706.30303757726 9762.788428253993 0.705595617701312 1.143435747889038 1.5032361942337398 1.3004932144943562 1.0941443313732486 0.9293221352718063 1.2855652507033575 1.21773884314637 1.0966439676796322 1.0 13.253077551001454 HEAFESDLAAHQDR ddPTM_PC-9_Lapatinib_30min_R1 1 HEAFESDLAAHQDR 14 0 O43707;O43707-2;P12814-4;P12814-3;P12814;P12814-2;H9KV75;P35609-2;P35609;A0A494C1A0;H7C5W8;Q08043;A0A087WSZ2;A0A494C060;F6THM6 O43707;P12814-4 ACTN4;ACTN1;ACTN2;ACTN3 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2;Alpha-actinin-3 0 103.83 0.0004728 5881000.0 11603.0 15082.0 15374.0 10725.0 11726.0 15626.0 15753.0 18017.0 18279.0 10575.0 False True 11437.5390922704 15047.07855563531 14110.009065356197 11513.75227755119 11036.299734203 14957.712405985105 16568.613259979025 18854.13559429222 16220.226533596691 12402.874659698236 0.9221684009623521 1.2131928257349178 1.137640220714727 0.9283132010487737 0.8898178879501403 1.205987548563119 1.3358687977245223 1.5201423953397384 1.307779605828197 1.0 13.598386917632668 -6.980920715842867 5.065501560551686 1.3277906885152604 1.0305298385166357 0.41173926771437863 0.15240020719684375 0.17099801949910215 12.211315031061316 0.05676668132045605 0.048168668853469286 1.04491095920616e-07 6.980920715842867 -0.2972608499986247 HEAMITDLEER ddPTM_PC-9_AZD4547_30min_R2 1 HEAMITDLEER 11 0 P35579 P35579 MYH9 Myosin-9 0 84.169 0.0082476 4941800.0 42260.0 41530.0 53532.0 52746.0 40946.0 47162.0 38599.0 49707.0 40652.0 42875.0 False True 55697.80093739389 54953.76033658628 52822.130702812574 40586.22461757647 35261.35467940742 44212.95268449059 42034.23622382892 42025.925303227436 42800.781727297144 41373.959300134346 1.3462042763021966 1.328220969570293 1.276699924211533 0.9809606163905294 0.852259616335363 1.0686178802410875 1.0159587560596945 1.01575788283552 1.0344860016130524 1.0 15.336435403096665 -5.7123511698576355 4.688391356990892 0.9933569671787595 1.3272615688513856 0.8809209634310089 0.054370704979032666 0.06569702949731711 3.0644286996243095 0.016108522094725145 0.027905573801724433 1.9393171145588387e-06 5.7123511698576355 0.33390460167262603 HEAMITDLEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HEAMITDLEER 11 0 P35579 P35579 MYH9 Myosin-9 0 60.161 0.043936 4725200.0 46195.0 53238.0 58289.0 66970.0 73717.0 53748.0 62251.0 51311.0 59856.0 43137.0 False True 54014.90110716091 58523.116802315315 59678.83082226348 63217.8880196695 59272.68303191224 50929.36026205361 56354.134621788886 49964.14061849838 60731.28076357326 50957.39662769591 1.0600011908340548 1.1484714815769719 1.1711514867662485 1.2406027819974987 1.1631811464971284 0.999449807731601 1.1059068624231834 0.9805081092259395 1.1918050132601385 1.0 15.637003952900074 -6.740224046005608 24.869313721256532 1.0574640287559338 1.1616917120706751 0.3379727955417079 0.07058228599803074 256.6643141849881 300869.6746872458 0.022717846960533437 0.02269611637827575 1.8187623443494267e-07 6.740224046005608 0.1042276833147413 HEAMITDLEER ddPTM_PC-9_Lapatinib_30min_R1 1 HEAMITDLEER 11 0 P35579 P35579 MYH9 Myosin-9 0 77.74 0.016086000000000003 5883100.0 42899.0 50587.0 36696.0 29443.0 45042.0 38545.0 40803.0 38155.0 38060.0 40854.0 False True 42287.252393286915 50469.86890955604 33678.99653065637 31608.336438968723 42392.71811597914 36896.52020278357 42915.57968938767 39927.82059167561 33773.282010432195 47915.55946546682 0.882536964297865 1.053308559319445 0.702882255917916 0.6596674815359119 0.884738038935598 0.7700321276510448 0.8956501847863703 0.8332955106253525 0.7048499983553966 1.0 15.548206593310711 -2.977667381914085 14.952697201961023 0.8322381017865418 0.8661246194440363 0.0 0.12366709222279476 0.0 0.0 0.028514526500464765 0.0 0.0010527678605103136 2.977667381914085 0.03388651765749451 HEAPS(ph)SPISGQPCGDDQNASPSK ddPTM_PC-9_AZD4547_30min_R2 2 HEAPSSPISGQPCGDDQNASPSK 23 0 O75376-2;O75376;A0A088AWL3;O75376-3;E7EVU5;E7EW50;J3KS51 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 HEAPS(0.548)S(0.438)PIS(0.014)GQPCGDDQNASPSK;HEAPS(0.543)S(0.457)PISGQPCGDDQNASPSK 112.39 2.3386999999999996e-07 82497000.0 236120.0 239890.0 412360.0 543080.0 486310.0 474820.0 329980.0 468720.0 397070.0 405860.0 True False 311201.24839889887 317429.7511953692 406891.8369687621 417881.2965023588 418794.25082163466 445129.4303390408 359347.58074403595 396290.0941140831 418058.3095655283 391650.96493417036 0.794588233559456 0.8104914314425946 1.0389144248301634 1.0669737442689495 1.0693047849174242 1.1365462368102661 0.9175199678224614 1.0118450600030884 1.0674257106344587 1.0 18.57920898726813 -5.255439062877143 6.108526033172683 1.040653881954033 0.8001845058662117 0.7537507768157756 0.053973059566438886 0.06992654712823636 12.318387027367702 0.014631140091520951 0.035730273165173805 5.553425333804019e-06 5.255439062877143 -0.24046937608782126 HEAPS(ph)SPISGQPCGDDQNASPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HEAPSSPISGQPCGDDQNASPSK 23 0 O75376-2;O75376;A0A088AWL3;O75376-3;E7EVU5;E7EW50;J3KS51 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 HEAPS(0.54)S(0.445)PIS(0.015)GQPCGDDQNASPSK 89.029 1.3505e-05 4648100.0 26741.0 27235.0 39512.0 47333.0 43030.0 40493.0 46234.0 33174.0 40955.0 33818.0 True False 31267.723141175225 29938.710810155466 40454.11593009446 44681.08546565646 34598.580393439566 38369.475796147504 41854.380814826865 32303.21765075845 41553.88939575219 39948.9356968593 0.7826922694121593 0.749424491238929 1.0126456493626907 1.1184549647256108 0.8660701415422097 0.9604630292857598 1.0476970183242547 0.8086127223984608 1.0401751303481928 1.0 15.285869447525817 -5.25834757652269 24.989392041971744 0.9772733537632082 0.7660583587629116 0.5068947175264822 0.08500858879662873 211.845143414189 1712210.190486674 0.021795937749690877 0.052829762418956594 5.516357749302407e-06 5.25834757652269 -0.2112149950002966 HEAPS(ph)SPISGQPCGDDQNASPSK ddPTM_PC-9_Lapatinib_30min_R1 1 HEAPSSPISGQPCGDDQNASPSK 23 0 O75376-2;O75376;A0A088AWL3;O75376-3;E7EVU5;E7EW50;J3KS51 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 HEAPS(0.544)S(0.456)PISGQPCGDDQNASPSK 110.01 6.210899999999999e-07 34477000.0 81808.0 103420.0 146550.0 106600.0 121530.0 139030.0 117440.0 113670.0 152560.0 102380.0 True False 80641.4029182502 103180.53734410596 134501.22469935947 114439.71960717555 114381.84433717291 133084.01099475933 123520.46856166674 118951.52317273666 135377.08627197947 120076.2465872249 0.6715849737997204 0.8592918272903736 1.1201318205899788 0.9530587677392555 0.9525767800718562 1.108329205627571 1.0286836245496724 0.9906332563978736 1.127426032372188 1.0 16.873591260616735 -4.958999707531737 3.140022583450493 1.0309383225208637 0.6708769831385016 0.7693204148578299 0.06296712828401474 0.12285525904549348 2.277729083094674 0.01611134825535398 0.08895998485718654 1.0990065795396392e-05 4.958999707531737 -0.36006133938236207 HEAPSS(ph)PISGQPCGDDQNAS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 1 HEAPSSPISGQPCGDDQNASPSK 23 0 O75376-2;O75376;A0A088AWL3;O75376-3;E7EVU5;E7EW50;J3KS51 O75376-2 NCOR1 Nuclear receptor corepressor 1 2 HEAPS(0.443)S(0.54)PIS(0.018)GQPCGDDQNAS(0.968)PS(0.032)K 118.76 4.6776e-08 8437500.0 18916.0 52064.0 66888.0 64642.0 58887.0 58420.0 50946.0 58604.0 66886.0 55845.0 True False 18646.254371230443 51943.44900680261 61388.72683514669 69395.98831939058 55423.38243629643 55921.51278367146 53583.734599307536 61326.95578442037 59352.59433919518 65497.73384121488 0.28468548875956934 0.7930571938981629 0.9372648981103745 1.0595173947182077 0.8461877867508891 0.8537930933494752 0.818100588475469 0.9363217960043371 0.9061778302602459 1.0 15.999157371198024 -4.759030123752038 2.9510026915858414 0.9127016355583109 0.1586321035492055 0.883589525764478 0.06892274081814541 0.14156417577544828 1.6798749612711616 0.018733812873206936 0.26413075515715784 1.7416860614981552e-05 4.759030123752038 -0.7540695320091053 down HEAPSS(ph)PISGQPCGDDQNASPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HEAPSSPISGQPCGDDQNASPSK 23 0 O75376-2;O75376;A0A088AWL3;O75376-3;E7EVU5;E7EW50;J3KS51 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 HEAPS(0.219)S(0.776)PIS(0.005)GQPCGDDQNASPSK;HEAPS(0.213)S(0.787)PISGQPCGDDQNASPSK 135.06 1.0888999999999999e-08 57894000.0 146843.0 166490.0 185630.0 250531.0 275051.0 205061.0 205745.0 196759.0 203584.0 171803.0 True False 171700.61961854834 183018.02690592164 190056.12320569533 236494.56030246062 221156.7310201246 194307.24017074096 186255.34413519394 191594.28473339346 206561.03085691156 202949.52390819983 0.8460262252017585 0.9017908659332761 0.936469914024846 1.165287583573905 1.0897129826239969 0.9574165853112914 0.9177422077592201 0.9440489489399212 1.0177950993880889 1.0 17.63076143011132 -5.529389629826259 24.994560390928473 1.01102648015829 0.8852139705569494 0.397993697587112 0.06930215725748667 183.2688812675023 703546.8542094292 0.02144315491606016 0.037257670807873816 2.955359858502076e-06 5.529389629826259 -0.1258125096013406 HEAPSS(ph)PISGQPCGDDQNASPSK ddPTM_PC-9_Lapatinib_30min_R1 1 HEAPSSPISGQPCGDDQNASPSK 23 0 O75376-2;O75376;A0A088AWL3;O75376-3;E7EVU5;E7EW50;J3KS51 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 HEAPS(0.444)S(0.555)PIS(0.001)GQPCGDDQNASPSK 111.72 3.4321999999999997e-07 37729000.0 109670.0 122260.0 189410.0 148030.0 174110.0 185080.0 157880.0 154570.0 182840.0 135920.0 True False 108106.08568898503 121976.91448163224 173837.44094374374 158916.6200136037 163869.19211343053 177164.55984255264 166054.25388722704 161751.88648552733 162246.6338094436 159413.59089798393 0.6781484883441781 0.765160070697428 1.0904806796240498 0.9968825061804282 1.0279499457376753 1.1113516660943192 1.0416568182915644 1.0146681068682517 1.017771652313338 1.0 17.282415106809573 -5.163343656459738 4.220212363497438 1.0390488058420564 0.698390872814667 0.9204005281999132 0.03741133412494855 0.05446406908456659 1.6673016044683509 0.009845820709575915 0.0292235960321247 6.865249790142172e-06 5.163343656459738 -0.34065793302738934 HECQANGPEDLNR ddPTM_PC-9_AZD4547_30min_R2 2 HECQANGPEDLNR 13 0 P60981;P60981-2 P60981 DSTN Destrin 0 ; 134.61 3.9739e-05 45484000.0 37127.0 36018.0 47779.0 53616.0 56330.0 46081.0 34346.0 60053.0 45789.0 43587.0 False True 48932.613710426485 47660.11412962107 47145.41924175598 41255.65955894247 48509.5518265769 43199.547785378294 37402.727462981624 50773.18873065596 48209.313059903805 42061.03239685027 1.163371674968463 1.1331180290569873 1.1208811708883888 0.9808522807926106 1.1533133891932126 1.0270681750696466 0.889248915958195 1.2071313003353217 1.1461752199766249 1.0 15.360196641305702 -5.540761326710689 24.198975002206197 1.0611485604093691 1.1429335799805604 0.15406286414181014 0.08857003387888925 321.84554060067416 435523.7444406508 0.024858855898474603 0.04306949267123319 2.8789801684000883e-06 5.540761326710689 0.08178501957119133 HECQANGPEDLNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HECQANGPEDLNR 13 0 P60981;P60981-2 P60981 DSTN Destrin 0 ;; 134.04 3.7643e-05 39526000.0 69546.0 77926.0 82842.0 85390.0 95281.0 83073.0 91648.0 74373.0 76362.0 66719.0 False True 81318.76420388803 85661.97828500724 84817.26746003459 80605.87513811514 76611.37203038161 78716.50563834148 82966.43796593965 72420.78755470738 77478.64978728918 78814.6265526864 1.0317724990998676 1.086879200369534 1.0761615092261525 1.0227273624678195 0.9720451061094358 0.9987550418160095 1.0526781841753425 0.9188749693090934 0.9830491264904473 1.0 16.266175771881663 -5.966660792462877 3.663624343802053 0.9876118919327737 1.0666948414843738 0.5150736435546399 0.033583315283901904 0.1852804010393873 5.311342455936522 0.010161529929015083 0.015141541162391985 1.0797897673077665e-06 5.966660792462877 0.07908294955160011 HECQANGPEDLNR ddPTM_PC-9_Lapatinib_30min_R1 2 HECQANGPEDLNR 13 0 P60981;P60981-2 P60981 DSTN Destrin 0 ; 148.48 9.731799999999999e-05 62369000.0 61683.0 76606.0 78700.0 57292.0 79088.0 72278.0 60770.0 64098.0 66793.0 47510.0 False True 60803.389108723204 76428.62351365856 72229.58979078513 61505.44480050937 74436.19933299047 69186.83842824724 63916.37325010637 67076.22708125353 59270.068978528645 55722.040196904294 1.0911910061775019 1.3716049025409633 1.2962481189767696 1.1037902521725396 1.3358484195832776 1.2416422331946668 1.147057304869776 1.2037647373324287 1.0636737055765855 1.0 15.7659604610362 -8.266637061291966 0.9525167929545182 0.9971095875390399 1.2451425571178778 0.4447369740224393 0.08794488096257222 0.47540227837621596 0.9020447725064062 0.0809594437229931 0.02861773221886661 5.412064187322378e-09 8.266637061291966 0.24803296957883791 HEDEQALLDQNS(ph)QTPPPSPFSVQAFNK ddPTM_PC-9_AZD4547_30min_R2 1 HEDEQALLDQNSQTPPPSPFSVQAFNK 27 0 A0A499FJI4;O75592-2;O75592;A0A087WY34 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 HEDEQALLDQNS(0.679)QT(0.321)PPPSPFSVQAFNK 116.38 3.8052e-12 5105900.0 27734.0 22337.0 36978.0 55604.0 36744.0 40076.0 32778.0 40921.0 31985.0 39255.0 True False 36552.8350969636 29556.998426157636 36487.64755900403 42785.35687323632 31642.729847607716 37570.04138466658 35695.17850060015 34597.599721032646 33675.661801328315 37880.694398292086 0.9649462787728529 0.7802654860384571 0.9632254143854643 1.129476572508802 0.8353260242514029 0.9917991732052434 0.9423052841979984 0.9133306627713914 0.8889927266709936 1.0 15.209175156918318 -5.374043558501743 24.944805235197098 0.9573440581152806 0.8723584135163087 0.14049159344280493 0.08452711993028925 37.67731272662105 8287.465559862558 0.021742546590524946 0.045260777774957614 4.2262622393117975e-06 5.374043558501743 -0.08498564459897184 HEDEQALLDQNS(ph)QTPPPSPFSVQAFNK ddPTM_PC-9_Lapatinib_30min_R1 1 HEDEQALLDQNSQTPPPSPFSVQAFNK 27 0 A0A499FJI4;O75592-2;O75592;A0A087WY34 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 HEDEQALLDQNS(0.618)QT(0.381)PPPS(0.001)PFSVQAFNK 109.18 1.9629e-10 21104000.0 46904.0 43039.0 40430.0 44211.0 41387.0 45329.0 28351.0 32969.0 39858.0 31550.0 True False 46235.14035885983 42939.34583980826 37106.0014643132 47462.424423572564 38952.69802997268 43390.38433705998 29818.876057491616 34500.86009925183 35368.772316652845 37003.37546226752 1.24948439922747 1.1604169971897205 1.002773422715188 1.282651213048663 1.0526795878309234 1.1726061148476932 0.8058420531904728 0.9323706193893714 0.9558255665815816 1.0 15.175369259495266 -7.247386636678042 24.758771132449397 0.9178737775957052 1.148198031528334 0.6118640440595472 0.0896103066097974 456.17638563446866 803713.5590878918 0.03333646129841289 0.02569025505022137 5.657354109935407e-08 7.247386636678042 0.2303242539326288 HEDEQALLDQNSQT(ph)PPPSPFSVQAFNK ddPTM_PC-9_AZD4547_30min_R2 3 HEDEQALLDQNSQTPPPSPFSVQAFNK 27 0 A0A499FJI4;O75592-2;O75592;A0A087WY34 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 HEDEQALLDQNS(0.09)QT(0.9)PPPS(0.01)PFSVQAFNK;HEDEQALLDQNS(0.046)QT(0.952)PPPS(0.002)PFSVQAFNK;HEDEQALLDQNS(0.224)QT(0.776)PPPSPFSVQAFNK 141.29 2.263e-10 45698500.0 73961.0 58979.0 100797.0 148045.0 116278.0 99388.0 87983.0 116143.0 93421.0 96898.0 True False 97479.05951563177 78042.80835279368 99460.36592041007 113915.51252244913 100134.80680437956 93173.25264844926 95813.31655434442 98195.76805063138 98359.0433372484 93505.63051345569 1.0424940079047358 0.8346321812306601 1.0636831747377766 1.2182743637673927 1.0708960118713913 0.9964453705816293 1.0246796479336786 1.050158878256008 1.0519050328535486 1.0 16.51276562015684 -5.307692130468523 22.36642104558753 1.0638780557911607 0.93856316580504 0.29342793315387883 0.074824086431403 133.56893817824295 64589.48015703101 0.0200362925900854 0.041709535391965334 4.9238846410099375e-06 5.307692130468523 -0.12531488998612073 HEDEQALLDQNSQT(ph)PPPSPFSVQAFNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HEDEQALLDQNSQTPPPSPFSVQAFNK 27 0 A0A499FJI4;O75592-2;O75592;A0A087WY34 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 HEDEQALLDQNS(0.047)QT(0.942)PPPS(0.01)PFSVQAFNK;HEDEQALLDQNS(0.009)QT(0.991)PPPS(0.001)PFSVQAFNK;HEDEQALLDQNS(0.032)QT(0.968)PPPSPFSVQAFNK;HEDEQALLDQNS(0.031)QT(0.968)PPPSPFSVQAFNK 153.34 3.5667e-12 48944000.0 119392.0 99559.0 138454.0 150945.0 178052.0 162612.0 157406.0 152566.0 151575.0 117373.0 True False 139602.7075005117 109442.55955749076 141755.26844971927 142488.0410202929 143163.98875697682 154084.34045793462 142495.36415924746 148561.304157039 153791.49762327303 138651.79577584352 1.0068582719707828 0.789333877322621 1.0223832129725394 1.027668197321089 1.0325433432425795 1.111304326032969 1.0277210140834943 1.0714704654616667 1.1091922521645927 1.0 17.08110677628212 -5.444380443535372 7.0414850499630735 1.0552757334952223 0.8981405525359174 0.5193668704965263 0.05923431448884691 0.17913269929629314 13.775870510542978 0.0145793464030865 0.030474074442418852 3.5943433143061806e-06 5.444380443535372 -0.1571351809593049 HEDEQALLDQNSQT(ph)PPPSPFSVQAFNK ddPTM_PC-9_Lapatinib_30min_R1 3 HEDEQALLDQNSQTPPPSPFSVQAFNK 27 0 A0A499FJI4;O75592-2;O75592;A0A087WY34 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 HEDEQALLDQNS(0.021)QT(0.949)PPPS(0.03)PFSVQAFNK;HEDEQALLDQNS(0.208)QT(0.792)PPPSPFSVQAFNK;HEDEQALLDQNS(0.018)QT(0.979)PPPS(0.003)PFSVQAFNK 137.62 1.7879000000000002e-11 27955400.0 145794.0 99137.0 112089.0 102127.0 113101.0 112532.0 82773.0 95598.0 103000.0 70252.1 True False 143714.95082465484 98907.45436745904 102873.47509605243 109637.7602656851 106448.62154512147 107719.2686849044 87058.5809286004 100039.83207765709 91399.05536191586 82395.08187996087 1.7442175861179336 1.200404831341203 1.2485390237966627 1.3306347631939166 1.2919293132107514 1.3073507086483347 1.0565992404186655 1.2141480995601457 1.1092780452002298 1.0 16.330270605803264 -4.76080311091089 24.999999993054637 1.2101828802840457 1.7442181978846643 0.7095293783450025 0.104958002787873 8.669687087876515 340383.2786359849 0.026153033313345994 0.15137713367600952 1.7345902027274513e-05 4.76080311091089 0.5340353176006185 HEDGTQS(ph)DSEDPLAK ddPTM_PC-9_AZD4547_30min_R2 2 HEDGTQSDSEDPLAK 15 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 HEDGT(0.001)QS(0.932)DS(0.067)EDPLAK;HEDGT(0.017)QS(0.542)DS(0.441)EDPLAK 164.93 9.8971e-16 2708200.0 33188.0 32740.0 38866.0 40162.0 38517.0 44366.0 39211.0 41210.0 40464.0 38650.0 True False 43741.093646716254 43322.56473440488 38350.61144540672 30903.271396714546 33169.57940181545 41591.78700649064 42700.703038227824 34841.941411591964 42602.84443110676 37296.87526414441 1.1727817233195146 1.1615601689842716 1.0282526665786216 0.8285753478770272 0.8893393660166281 1.1151547337928112 1.144886876871383 0.9341785649557481 1.142263101918977 1.0 15.186767145961337 -5.2809447619552685 4.883068749471016 1.0048604704479651 1.1694993480910199 0.28267065107617084 0.10014888790333887 0.2369646738290023 16.324948245339503 0.02839846536618322 0.06716624560945898 5.236670377169226e-06 5.2809447619552685 0.16463887764305474 HEDGTQS(ph)DSEDPLAK ddPTM_PC-9_Lapatinib_30min_R1 2 HEDGTQSDSEDPLAK 15 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 HEDGT(0.05)QS(0.881)DS(0.069)EDPLAK;HEDGT(0.014)QS(0.968)DS(0.018)EDPLAK 80.859 0.0053357 11027100.0 69073.0 82946.0 91192.0 96432.0 103351.0 82749.0 107883.0 102325.0 99921.0 83252.0 True False 68088.00635356312 82753.94363318718 83694.54577129966 103523.93096772161 97272.09737588397 79210.01816734043 113468.65386442692 107079.39305577791 88666.84476522326 97641.99727368273 0.6973229578940081 0.8475240771779226 0.8571572490135625 1.0602397928992817 0.9962116721479799 0.8112289832142727 1.162088619985756 1.0966530391184328 0.908081022930094 1.0 16.57521418539534 -4.072656687447068 0.6236481055041357 1.0182713839946742 0.09541283385471344 0.507055125462121 0.09597361512504166 6.429159585218203 0.9903386973716842 0.04504028979565568 5.178321183257523 8.459473076460718e-05 4.072656687447068 -0.9228585501399608 HEEAPGHRPTTNPNASK ddPTM_PC-9_AZD4547_30min_R2 1 HEEAPGHRPTTNPNASK 17 1 E9PP21;P21291;E9PND2;E9PS42 E9PP21 CSRP1 Cysteine and glycine-rich protein 1 0 45.14 0.03269 979670.0 2376.3 1184.9 4194.0 3288.3 3723.8 4463.4 3962.5 2727.6 2370.8 3820.9 False True 3131.9139698894737 1567.895753017603 4138.384819689079 2530.2332387285614 3206.814647466841 4184.302892412437 4315.154823620358 2306.1120940125743 2496.1156479158717 3687.1314539914474 0.8494174967640681 0.42523456854794306 1.1223860259197254 0.6862335314867867 0.8697315752047172 1.1348396292957725 1.1703284456942953 0.6254488408641162 0.6769803786663858 1.0 11.84828313712334 -5.2607729889656145 24.99998325030917 0.90515811504996 0.6373260499284942 0.21012006576002307 0.21182607638274445 93.59253794193025 3510998.373905496 0.05648000349511297 0.1324240851796328 5.485636309077833e-06 5.2607729889656145 -0.26783206512146585 HEEQPAPGYDTHGR ddPTM_PC-9_Lapatinib_30min_R1 2 HEEQPAPGYDTHGR 14 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 0 ; 78.505 0.0058347 7313200.0 39041.0 41690.0 45209.0 35373.0 36441.0 35116.0 23994.0 29926.0 37695.0 30942.0 False True 38484.268180757455 41593.46936642594 41492.09053178667 37974.448420868845 34297.61202576252 33614.17053939418 25236.29191645633 31316.47121023417 33449.39215405261 36290.28347237663 1.0604565326708137 1.1461323910044952 1.1433388378839626 1.0464081508146434 0.9450907720759226 0.9262581419343432 0.695400793318841 0.8629436921888908 0.9217175770895689 1.0 15.147295705658367 -6.33826206131545 1.6905440008281318 0.8600206529733159 1.1193027716703654 0.6454158335126363 0.07706500113130671 0.21678120966163933 1.229333236045844 0.028645885210131367 0.036102052877910164 4.5892100785404356e-07 6.33826206131545 0.25928211869704954 HEEQS(ph)NEDIPIAEQSSK ddPTM_PC-9_AZD4547_30min_R2 2 HEEQSNEDIPIAEQSSK 17 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 HEEQS(1)NEDIPIAEQSSK;HEEQS(1)NEDIPIAEQSSK 125.75 2.1434000000000002e-05 10256300.0 44748.0 50746.0 57078.0 47347.0 48400.0 61313.0 54706.0 71508.0 59563.0 57322.0 True False 58976.93318377901 67148.65210788371 56321.10842589735 36431.88065385799 41680.49544481314 57479.0884174584 59574.72802043535 60458.081690369276 62711.37857972549 55315.17422745888 1.0661980913458355 1.213928240228711 1.0181855017630788 0.6586236265667029 0.7535092499830294 1.0391197211293486 1.0770051591171161 1.0929746228722428 1.1337102242840822 1.0 15.755387678810866 -6.984715434955674 24.94451050620247 1.080012157066682 0.9407350170908999 0.15678883523999132 0.14848465157650922 501.79963835405465 818937.3117965714 0.06062873443962214 0.053451146502061356 1.0358206505530239e-07 6.984715434955674 -0.13927713997578217 HEEQS(ph)NEDIPIAEQSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HEEQSNEDIPIAEQSSK 17 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 HEEQS(1)NEDIPIAEQSSK 79.461 0.0036125999999999997 2775900.0 13543.0 23603.0 22468.0 14733.0 19168.0 13481.0 20042.0 12884.0 15211.0 12429.0 True False 15835.56241355731 25946.149853207247 23003.722330364508 13907.557775030471 15412.167998639317 12774.032628055835 18143.476668485535 12545.8086517264 15433.432098615212 14682.279312090142 1.0785493230957333 1.7671745170957112 1.5667677913893152 0.947234246087273 1.049712219133997 0.8700306237558797 1.2357397841863194 0.8544864448529825 1.051160502436875 1.0 13.841788332539162 -5.762280355806249 24.999999761653417 1.0014608179635345 1.5004650156144779 0.5646716438402402 0.1884266185555866 14.43310156234864 429083.6477220797 0.04990872751022927 0.07919236756852405 1.728700048551881e-06 5.762280355806249 0.4990041976509434 HEEQS(ph)NEDIPIAEQSSK ddPTM_PC-9_Lapatinib_30min_R1 2 HEEQSNEDIPIAEQSSK 17 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 HEEQS(1)NEDIPIAEQSSK;HEEQS(1)NEDIPIAEQSSK 102.15 0.00056214 9694100.0 60519.0 82981.0 73096.0 60845.0 83210.0 80466.0 84195.0 79845.0 72366.0 68174.0 True False 59655.98796217463 82788.8625928376 67086.32903871966 65319.74427296987 78315.75139715442 77024.65675540753 88554.20513070111 83554.89018850322 64215.37903223689 79957.7850638549 0.7460935531735015 1.035407152996069 0.8390218536587026 0.8169278853935864 0.9794637424562332 0.9633165387697402 1.1075119834795455 1.044987553391776 0.803116031552825 1.0 16.286950887629345 -6.3556057949786995 6.414804021376553 0.9915865105327609 0.8707783000703203 0.2651855904466647 0.0996562993644106 0.35377206895313806 20.201228533959693 0.031077202838528273 0.035285141612898245 4.409549325594151e-07 6.3556057949786995 -0.12080821046244061 HEERQDEHGYISR ddPTM_PC-9_AZD4547_30min_R2 2 HEERQDEHGYISR 13 1 P04792 P04792 HSPB1 Heat shock protein beta-1 0 ; 59.155 0.01761 11274400.0 9609.8 561.09 16136.7 133616.0 64122.0 15092.9 5553.6 11259.9 5592.3 24864.1 False True 12665.516503742738 742.4513697870262 15922.716814467529 102812.89554662144 55219.76712628736 14149.138577069434 6047.8596412512325 9519.941181761324 5887.897561093274 23993.61542704302 0.5278702804191623 0.03094370550551606 0.6636230735165137 4.285010562882566 2.30143586714529 0.5897043161374524 0.2520612060171114 0.39676976613668113 0.24539434579988598 1.0 14.550362943002726 -6.894362447235378 7.619549071632239 0.42371226500354336 1.5755049544781266 0.18380025525877575 1.1215972352928179 0.4511815152303595 29.26124317784581 0.4482212616125892 0.39536046639576344 1.275373981285518e-07 6.894362447235378 1.1517926894745831 HEERQDEHGYISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HEERQDEHGYISR 13 1 P04792 P04792 HSPB1 Heat shock protein beta-1 0 53.946999999999996 0.023577 2992900.0 3385.8 0.0 867.99 10355.0 10111.0 17756.0 5189.4 27096.0 16054.0 6619.0 False True 3958.9490674017848 0.0 888.6861734704056 9774.842921362955 8129.822132420811 16824.844102348445 4697.822463997547 26384.75871058512 16288.759378815905 7818.972304024827 0.5063260123538115 0.0 0.11365766994889509 1.2501442058224634 1.0397558421118813 2.151797377986341 0.6008235201932275 3.374453532339989 2.083235333936564 1.0 12.932763282307283 -6.244615623486727 0.9379772276859287 2.0075682066659546 0.10404049582443879 0.4517382877859013 0.7382725909349006 0.4951761600567577 0.9246591533056803 0.34912237480679764 0.5694613661659753 5.693566224737722e-07 6.244615623486727 -1.9035277108415158 HEERQDEHGYISR ddPTM_PC-9_Lapatinib_30min_R1 2 HEERQDEHGYISR 13 1 P04792 P04792 HSPB1 Heat shock protein beta-1 0 ; 59.155 0.01761 3934400.0 35886.0 1428.13 10708.0 3452.77 2714.3799999999997 4069.7999999999997 548.2 1235.63 7780.599999999999 814.7 False True 35374.259059313576 1424.8232527290452 9827.629574075325 3706.698223903071 2554.725505076405 3895.744141167169 576.5831136367993 1293.0418806890875 6904.266894649733 955.5198094804865 37.02095833946809 1.4911498836468056 10.28511337658042 3.8792479100128676 2.673649964897538 4.077094061802104 0.6034235061545045 1.3532339862133373 7.225665890070416 1.0 9.900141972703269 -4.759089537624884 24.999999938897094 3.73867028481039 37.021001616704524 0.922484110763283 2.904401832665264 15.707135743465853 167071.5840493351 0.7249918708815347 4.7229789783875615 1.7414478055670045e-05 4.759089537624884 33.282331331894135 HEGVFICR ddPTM_PC-9_AZD4547_30min_R2 1 HEGVFICR 8 0 M0R2U2;M0R1H0;M0R2B0;M0R0P1;M0R299;M0QXL5;M0R2Q4;P22087 M0R2U2 FBL rRNA 2-O-methyltransferase fibrillarin 0 77.923 0.019183000000000002 2144900.0 8720.2 11265.0 14621.0 14297.0 13164.0 14274.0 13260.0 15310.0 14946.0 15032.0 False True 11493.042208572226 14906.190950918468 14427.115986808312 11001.04753644808 11336.405827180166 13381.444523523585 14440.114311976251 12944.1912888006 15736.015047136252 14505.734255384697 0.792310268906648 1.027606785598262 0.9945801937914862 0.7583930149805663 0.7815120301802 0.9224934283182692 0.9954762756401602 0.8923499535361725 1.0848134103445926 1.0 13.82433570368182 -8.252320291596185 24.181840277960667 1.0424067038188454 0.8991409124919781 0.29012090318732275 0.09172789630589645 514.7704789811563 1365073.4356440224 0.06812964752007618 0.024872825998607784 5.593449332068594e-09 8.252320291596185 -0.14326579132686723 HEGVFICR ddPTM_PC-9_Lapatinib_30min_R1 2 HEGVFICR 8 0 M0R2U2;M0R1H0;M0R2B0;M0R0P1;M0R299;M0QXL5;M0R2Q4;P22087 M0R2U2 FBL rRNA 2-O-methyltransferase fibrillarin 0 ; 116.73 0.0030026999999999996 7181300.0 24459.0 35311.0 39864.0 39911.0 39678.0 38585.0 40425.0 36051.0 37873.0 37796.0 False True 24110.210174768727 35229.23954900137 36586.53579949002 42846.188079193074 37344.21804994941 36934.80949602812 42518.0086989559 37726.06107064598 33607.3439196295 44328.98823999569 0.5438926339630591 0.7947223915481992 0.8253410973742895 0.9665501014195319 0.8424333496575432 0.8331976650598085 0.9591468334166526 0.8510471943640653 0.7581346936609615 1.0 15.435962814513754 -4.559617898952758 1.584818049471575 0.8788033001618181 0.24985368196296828 0.6735547628062735 0.07057235078589601 1.116944166176024 1.742210365403796 0.01922642605381357 1.2869417834066483 2.756652995633274e-05 4.559617898952758 -0.6289496181988498 HEHPPNPPVS(ph)PGK ddPTM_PC-9_AZD4547_30min_R2 2 HEHPPNPPVSPGK 13 0 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 HEHPPNPPVS(1)PGK;HEHPPNPPVS(1)PGK 94.569 0.0021166 26945000.0 57142.0 64992.0 59820.0 59763.0 61457.0 59891.0 69548.0 77523.0 61348.0 61151.0 True False 75311.96737256428 85999.39301216982 59026.747714306315 45985.56367914574 52924.75637503884 56146.00630225237 75737.63726767169 65543.60165131878 64590.730035575776 59010.12210291581 1.276255067583447 1.4573668033118747 1.0002817416876635 0.7792826389842955 0.8968759000826355 0.9514639912849473 1.2834685740114633 1.1107179466093688 1.0945703505396445 1.0 15.848674823094452 -5.269248332692635 24.804956780434836 1.0132782902518982 1.366810940124979 0.5272453022245563 0.13340769682955436 405.42793833738773 1287836.2244716643 0.0393812262963052 0.0845311831616571 5.379620839831934e-06 5.269248332692635 0.35353264987308086 HEHPPNPPVS(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HEHPPNPPVSPGK 13 0 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 HEHPPNPPVS(1)PGK;HEHPPNPPVS(1)PGK 75.376 0.010445 23380000.0 89280.0 111342.0 81141.0 89106.0 103934.0 72897.0 88339.0 69674.0 68046.0 74070.0 True False 104393.34063962162 122395.29792635703 83075.70916895615 84113.67970554989 83568.87879646168 69074.15299216576 79970.89040102517 67845.13132570514 69041.0440196154 87498.30466220248 1.1930898666282097 1.398830507618159 0.9494550721831665 0.9613178224455966 0.9550914057031068 0.7894341868546444 0.913970741601934 0.7753879528023916 0.789055791265402 1.0 16.416967443590096 -5.371039289045388 4.462926001519541 0.8796505181154068 1.294091320285895 0.7709068754808001 0.08846065065287143 0.09545551058769301 3.0700423835546755 0.023964419905295364 0.05281685161192886 4.255599125316628e-06 5.371039289045388 0.4144408021704882 HEHPPNPPVS(ph)PGK ddPTM_PC-9_Lapatinib_30min_R1 3 HEHPPNPPVSPGK 13 0 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 HEHPPNPPVS(1)PGK;HEHPPNPPVS(1)PGK;HEHPPNPPVS(1)PGK 99.39200000000001 0.0021109 18194900.0 58506.0 74509.0 71475.0 80179.0 86582.0 75054.0 72810.0 78370.0 76408.0 72294.0 True False 57671.69371131362 74336.47898831942 65598.6014014788 86075.63112930328 81489.41698676141 71844.11537941941 76579.74553793394 82011.35630375115 67802.12642808999 84789.92157430004 0.6801715656828017 0.8767136188842864 0.7736603617918882 1.0151634714495708 0.9610743290445616 0.847319045064378 0.9031703782250623 0.9672300054185794 0.7996484153918704 1.0 16.371605170766152 -4.026996383760978 0.9777670022283181 0.9167081702283068 4.687687179385654e-16 0.456167071251839 0.07596259440402708 6.73501347202754 1.7716914094716327 0.023974761532748523 9.27428885081561 9.397311353894865e-05 4.026996383760978 -0.9167081702283063 HELIEFR ddPTM_PC-9_AZD4547_30min_R2 1 HELIEFR 7 0 A0A087WVQ6;Q00610-2;Q00610;J3KS13;K7EJJ5;J3KRF5 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 67.032 0.037981 0.0 7997.3 10475.0 9840.8 14491.0 12099.0 11659.0 9468.1 11921.0 9372.3 10483.0 False True 10540.275045826324 13860.838900210481 9710.30456213551 11150.32383371821 10419.262693942022 10929.96088691057 10310.742557859903 10078.88336732802 9867.700644070328 10115.993360776869 1.0419416729447983 1.370190588890029 0.9598962964710562 1.1022470494051322 1.0299791945634358 1.0804634302440064 1.0192516137701457 0.9963315522138699 0.975455429056601 1.0 13.304350374809005 -5.2826857598969275 24.99758231754739 1.025683802615059 1.2060661847405838 0.43549869579142764 0.08436134398904747 602.5850301979024 708974.8336076792 0.020456694699445076 0.04264985041662419 5.215719656032693e-06 5.2826857598969275 0.18038238212552482 HELIEFR ddPTM_PC-9_Lapatinib_30min_R1 2 HELIEFR 7 0 A0A087WVQ6;Q00610-2;Q00610;J3KS13;K7EJJ5;J3KRF5 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 ; 143.11 0.0016780999999999999 6745200.0 26997.0 29056.0 32025.0 31138.0 38612.0 30766.0 35206.0 34605.0 31953.0 33748.0 False True 26612.017829356544 28988.7226171953 29392.02812007495 33427.99239332296 36340.91807411278 29450.209899048885 37028.79441571901 36212.87463176344 28354.116659993193 39581.29683361666 0.6723381990545287 0.7323843566584455 0.7425736514805675 0.8445401001852052 0.9181335878628463 0.7440435825750061 0.9355124106057638 0.9148986397284388 0.7163513812895552 1.0 15.272531260878225 -3.039125054685923 0.3224515345201825 0.8994006064827558 9.488214703736773e-25 0.4370754384930905 0.08112980457363576 21.41813609112843 0.7342873220380844 0.07711743238218798 9.416611087797643 0.0009138500613186995 3.039125054685923 -0.8994006064827558 HELQANCYEEVK ddPTM_PC-9_Lapatinib_30min_R1 1 HELQANCYEEVK 12 0 P23528;G3V1A4;E9PP50;E9PK25 P23528 CFL1 Cofilin-1 0 103.76 0.0016737000000000002 8135800.0 61432.0 78729.0 74699.0 79234.0 80952.0 67012.0 84773.0 87412.0 60822.0 77595.0 False True 60555.96841475094 78546.70783759526 68557.53656647868 85061.13267687564 76190.56251775549 64146.05297260167 89162.13114252531 91473.48063319466 53971.585875946075 91007.19236116156 0.6653976113715815 0.8630824201880997 0.7533199826054238 0.9346638487572607 0.8371927596161152 0.7048459721517217 0.9797262043716926 1.0051236419884555 0.5930474776296814 1.0 16.473692946550266 -9.587332715649152 0.024550677923695485 1.8143920812712546 4.640318136130072e-06 0.13233916962870207 0.13131541472211347 1206.3274431032216 8.659130648852644 349.3761869313869 290.19977854540303 2.586230828807526e-10 9.587332715649152 -1.8143874409531184 HELQANCYEEVKDR ddPTM_PC-9_AZD4547_30min_R2 4 HELQANCYEEVKDR 14 1 P23528;G3V1A4;E9PP50;E9PK25 P23528 CFL1 Cofilin-1 0 ;;; 241.41 1.7196e-27 236426300.0 1047186.0 1034711.0 1197122.0 1197254.0 1255282.0 1257558.0 1220133.0 1409868.0 1220073.0 1185236.0 False True 1380169.3651780856 1369161.0958735733 1181247.3800943797 921245.587689908 1081007.7620445427 1178922.6994614888 1328722.473289181 1192005.2961436168 1284563.5679516038 1143741.2483977608 1.2067146892809288 1.1970898993033587 1.032792497209627 0.8054667862861976 0.9451506304934792 1.0307599740002495 1.1617334560159966 1.04219839742028 1.123124281607503 1.0 20.125329273646358 -5.272665690751826 5.438986699629487 1.0139674433910615 1.2039873218106323 0.3951856936698863 0.09130609597458039 0.17477612831417758 18.658732237202702 0.026851238374767335 0.06326691280564185 5.337456016743174e-06 5.272665690751826 0.1900198784195708 HELQANCYEEVKDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 HELQANCYEEVKDR 14 1 P23528;G3V1A4;E9PP50;E9PK25 P23528 CFL1 Cofilin-1 0 ;;;; 79.88600000000001 0.005517899999999999 313088800.0 653632.0 694361.0 651746.0 780688.0 788527.0 605689.0 708627.0 565972.0 565650.0 491368.0 False True 764278.9877795405 763292.5712080159 667286.0964004688 736948.5823846438 634020.7948384305 573925.6025854546 641500.7205448002 551115.8346969037 573921.5611453343 580449.1287330525 1.3167027909021654 1.3150033886243504 1.1496030631606866 1.2696178629696335 1.0922934731977443 0.9887612439666559 1.1051799180834418 0.9494644877834951 0.9887542813580132 1.0 19.14681010752158 -6.122707388546264 0.6599221670838156 0.9802188050747799 1.3415403540103523 0.8197385940962748 0.056778193585839624 0.3744963357371188 0.33052634844036183 0.03536269455012634 0.079874090456538 7.538633176998491e-07 6.122707388546264 0.36132154893557245 HELQANCYEEVKDR ddPTM_PC-9_Lapatinib_30min_R1 1 HELQANCYEEVKDR 14 1 P23528;G3V1A4;E9PP50;E9PK25 P23528 CFL1 Cofilin-1 0 100.22 0.00090606 169710000.0 549850.0 910860.0 850950.0 745860.0 988420.0 909920.0 1010400.0 934620.0 840100.0 789430.0 False True 542009.0381698592 908750.9596330698 780988.1757619915 800713.0325160206 930283.0789084878 871004.8427271195 1062713.5680748315 978045.8571980568 745479.0913548113 925881.9236506453 0.5853975807549847 0.9814976795852866 0.84350731536333 0.8648111730693496 1.0047534735752148 0.9407299359435036 1.1477851990939352 1.0563397256334102 0.8051556816396993 1.0 19.820468694892817 -4.43385686643775 2.104225564499883 0.9662433446115888 9.970664013286953e-35 0.5508910829864475 0.09990146065738938 2.338671891790191 4.412385874336835 0.027744816305553217 6.182596754278082 3.682503205568766e-05 4.43385686643775 -0.9662433446115888 HELS(ph)PPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HELSPPQK 8 0 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;C9JUL9 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 1 HELS(1)PPQK 67.207 0.026611000000000003 5561700.0 51993.0 139030.0 85572.0 52151.0 68071.0 42758.0 67781.0 36778.0 39151.0 42195.0 True False 60794.38799144098 152831.9795827394 87612.36101361709 49229.148545823205 54732.97620176221 40515.6952088429 61360.29298805606 35812.61646951209 39723.50930858485 49844.61948456382 1.2196780438913402 3.0661680470861925 1.7577094964231679 0.987652209102906 1.0980719036025994 0.8128398938102045 1.2310314257100206 0.7184851010970754 0.7969467862200587 1.0 15.605150159762017 -5.6541381155711 3.772737631549455 0.9468109353935223 2.197722750156645 0.558731946343709 0.4399942360012934 0.14250880783507544 3.8130661358897986 0.11448077484923758 0.20808883135841716 2.2174910948022453e-06 5.6541381155711 1.2509118147631226 HELS(ph)PPQKR ddPTM_PC-9_AZD4547_30min_R2 1 HELSPPQKR 9 1 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;C9JUL9 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 1 HELS(1)PPQKR 60.641000000000005 0.031712 147870000.0 627390.0 715890.0 645530.0 598560.0 563940.0 723620.0 711300.0 878930.0 802350.0 636560.0 True False 826886.9694773195 947287.4425080358 636969.8504181904 460571.2396598144 485646.66531297367 678371.9270079974 774604.3220293162 743111.5643021229 844760.5829700112 614274.2281537838 1.346120236824111 1.5421246718344856 1.0369470526748594 0.7497811540035995 0.7906023776589107 1.1043470422759893 1.2610073588101007 1.2097391201573975 1.37521736099683 1.0 19.22852333080607 -5.26838397517128 24.54090179429505 1.0606571808161267 1.4441224623816815 0.3908637354696759 0.18874490536431762 425.26616374870747 1502816.7771552787 0.056212248631241225 0.12139554769928883 5.390338328225911e-06 5.26838397517128 0.3834652815655548 HELS(ph)PPQKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HELSPPQKR 9 1 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;C9JUL9 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 1 HELS(1)PPQKR;HELS(1)PPQKR 63.693999999999996 0.025863999999999998 126650000.0 624130.0 886200.0 703780.0 690710.0 653650.0 492510.0 695630.0 389641.0 498780.0 496676.0 True False 729782.8818705999 974176.0793082328 720560.7843005124 652011.7580120352 525571.974765787 466681.90858569706 629734.8904749326 379413.3366087647 506073.7139009461 586719.427114948 1.243836232693252 1.6603780858229116 1.2281181617654917 1.1112837378133982 0.8957807607465139 0.7954089928136406 1.0733152191184512 0.6466691216863889 0.8625480775188272 1.0 19.16231123692227 -5.843816483177303 1.6617173267293184 0.8637451205787123 1.4523154226645898 0.7009409189453268 0.14826375085522353 0.18671167686963347 1.0509465727452751 0.04616973262964237 0.09076478254162461 1.432793216915852e-06 5.843816483177303 0.5885703020858775 HELS(ph)PPQKR ddPTM_PC-9_Lapatinib_30min_R1 2 HELSPPQKR 9 1 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;C9JUL9 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 1 HELS(1)PPQKR;HELS(1)PPQKR 105.4 0.0038766 18977700.0 46776.0 68279.0 52754.0 56982.0 68359.0 64387.0 60846.0 63906.0 62874.0 52576.0 True False 46108.9656623322 68120.90417054933 48416.76975632894 61172.64636637963 64338.2580189649 61633.31810342787 63996.30815823552 66875.30606032307 55792.468027428156 61663.69154688359 0.7477490319773517 1.1047166081316466 0.7851746877579837 0.9920367209911426 1.0433734407556157 0.9995074339097486 1.0378280403400504 1.084516745311575 0.9047863763558256 1.0 15.912133639688067 -5.976949675944105 24.90207692961579 1.0166954035248392 0.8995706847373778 0.26071513315789174 0.09852763157035818 313.5847889493906 338774.1061843368 0.025794378760663043 0.03825656419353698 1.0545090809956522e-06 5.976949675944105 -0.11712471878746145 HEMLPASLIQAQR ddPTM_PC-9_Lapatinib_30min_R1 1 HEMLPASLIQAQR 13 0 P52209-2;P52209 P52209-2 PGD 6-phosphogluconate dehydrogenase, decarboxylating 0 101.39 0.002577 0.0 31989.0 31396.0 35778.0 30156.0 29835.0 30779.0 33141.0 30650.0 30784.0 24937.0 False True 31532.830993935855 31323.30449096449 32836.470947073896 32373.772837466997 28080.163957866826 29462.653919353354 34856.87881984161 32074.11089332612 27316.781750108905 29247.327223536144 1.0781440216034681 1.0709800677361638 1.1227169818324276 1.1068967974418844 0.9600933358200995 1.007362269180068 1.1917970675895233 1.0966510084215553 0.9339924137794829 1.0 14.836017169116076 -8.256695053453157 24.954581341978685 0.9669962028873282 1.078792374207344 0.3515360235285322 0.061024502770227765 424.2721019974324 2231649.1816949844 0.047354345151763455 0.016620476334735394 5.537387889442835e-09 8.256695053453157 0.11179617132001574 HEQNIDCGGGYVK ddPTM_PC-9_AZD4547_30min_R2 1 HEQNIDCGGGYVK 13 0 P27797 P27797 CALR Calreticulin 0 104.9 0.0010809 10114000.0 56400.0 57388.0 72905.0 81857.0 79920.0 74013.0 53869.0 89015.0 66413.0 62376.0 False True 74334.026807123 75937.54871649442 71938.23206471917 62986.133328043055 68824.48751961696 69384.95540980474 58663.23664191926 75259.77711120737 69923.45559517329 60192.23522577674 1.2349437851626777 1.2615837978380124 1.1951413964755426 1.0464162543854136 1.1434113928725402 1.152722691715082 0.9745980760122578 1.2503236809351466 1.1616690314439304 1.0 15.877289771455121 -5.556970048900229 6.142435790570265 1.112938434615149 1.2440063091199145 0.3652568378239234 0.07778588626736739 0.18982794003208334 20.50373202984473 0.020971991910382695 0.037468659489153275 2.7735113731457535e-06 5.556970048900229 0.13106787450476554 HEQNIDCGGGYVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HEQNIDCGGGYVK 13 0 P27797 P27797 CALR Calreticulin 0 151.3 0.00011148 9495000.0 68153.0 68551.0 71285.0 82836.0 92452.0 67171.0 70599.0 71661.0 74122.0 57084.0 False True 79689.95681689211 75356.29024222387 72984.70474986805 78194.96747793566 74336.69427223514 63648.43451221266 63911.3516275027 69779.97468110574 75205.8940249528 67432.87732330467 1.1817671139082688 1.1175007390079272 1.0823311661453408 1.1595970775951396 1.1023805778868125 0.9438783726675696 0.9477773181927543 1.0348064245656907 1.115270429057634 1.0 16.04116453752241 -6.608546031300772 6.511064110666728 1.0072071613794107 1.1303292490464358 0.5864113838194112 0.05104024490953604 0.16775569404465338 10.42808761332195 0.018087770102729557 0.01807687254274284 2.4629407748766433e-07 6.608546031300772 0.12312208766702515 HEQNIDCGGGYVK ddPTM_PC-9_Lapatinib_30min_R1 2 HEQNIDCGGGYVK 13 0 P27797 P27797 CALR Calreticulin 0 ; 122.78 0.00014818 27065000.0 158856.0 167919.0 175800.0 168016.0 150563.0 158907.0 157213.0 153354.0 161258.0 138873.0 False True 156590.6843093774 167530.19387241302 161346.4026076248 180372.45712494582 141707.1803582473 152110.91804030933 165352.71989088296 160479.38668630086 143095.42591797898 162877.0130133589 0.9614044450614654 1.0285686775129679 0.9906026616192393 1.1074150599148818 0.8700256576207271 0.9339004640748996 1.0151998543669327 0.9852795291201627 0.8785489325387035 1.0 17.313423483753283 -6.265394066326649 24.999909127036386 0.949162162060926 1.0202245603406765 0.2969321545735385 0.056338919101543185 476.17104773124646 3010151.401673762 0.017369596799261575 0.0204300893897224 5.427576253279228e-07 6.265394066326649 0.07106239827975058 HEQVVER ddPTM_PC-9_Lapatinib_30min_R1 1 HEQVVER 7 0 K7ERQ7;A0A0A0MSN0;K7EJH0;K7EMX1;K7EJV2;K7ESQ2;Q8NBT2-2;Q8NBT2 K7ERQ7 SPC24 Kinetochore protein Spc24 0 69.598 0.034015 0.0 0.0 606.07 845.5 0.0 0.0 608.28 0.0 607.25 1224.2 0.0 False True 0.0 604.6666821518301 775.9862537243831 0.0 0.0 582.2652823699359 0.0 635.4650518751148 1086.3177046024985 0.0 0.0 HERPAGPGT(ph)PPPDSGPLAK ddPTM_PC-9_Lapatinib_30min_R1 1 HERPAGPGTPPPDSGPLAK 19 1 H0YME5;Q9P2K8-2;Q9P2K8 H0YME5 EIF2AK4 Eukaryotic translation initiation factor 2-alpha kinase 4 1 HERPAGPGT(0.997)PPPDS(0.003)GPLAK 49.497 0.040754000000000005 14135000.0 30036.0 35668.0 46607.0 41375.0 54628.0 41465.0 48492.0 42570.0 45054.0 33559.0 True False 29607.681132072194 35585.4129374354 42775.15236822274 44417.855522953876 51414.888442780284 39691.638609636015 51002.67848682176 44547.95760942553 39979.54408034714 39359.628435443294 0.7522347722523345 0.9041094733859526 1.0867773418740858 1.128513080244316 1.30628490375893 1.0084352974707897 1.2958119909712844 1.1318185506372858 1.0157500380350546 1.0 15.264428980895465 -5.075766726998449 1.792993200423549 1.1416512050749719 0.7241730271899738 0.5862275455957022 0.10251385709774295 0.33236104467360755 1.6313142335222548 0.027953484097022543 0.19386859984489732 8.399110075655005e-06 5.075766726998449 -0.4174781778849981 HES(ph)EEGDSHR ddPTM_PC-9_Lapatinib_30min_R1 1 HESEEGDSHR 10 0 Q6UN15;Q6UN15-5;Q6UN15-3;H0Y8P7 Q6UN15;H0Y8P7 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 HES(1)EEGDSHR 128.57 0.00015606 462240.0 437.7 0.0 0.0 0.0 675.13 359.19 740.54 1289.0 0.0 441.32 True False 431.4583177356508 0.0 0.0 0.0 635.4201807566499 343.828281012786 778.8815377099511 1348.8916457258522 0.0 517.6015739780636 0.8335722676027573 0.0 0.0 0.0 1.2276241277109785 0.664272093243978 1.504789739574789 2.606042395425597 0.0 1.0 9.015698194212746 -6.268027951074538 23.895822436940314 1.2391645587978737 0.17862261000054697 0.33107881051785326 0.662340703043889 311.2407831268116 1128824.9255212585 0.20297597805624198 0.23579525852236607 5.394759008757938e-07 6.268027951074538 -1.0605419487973267 HEVSASTQS(ph)TPASSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HEVSASTQSTPASSR 15 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 HEVSASTQS(0.443)T(0.443)PAS(0.036)S(0.078)R 93.75299999999999 0.0062896 0.0 2285.3 3378.1 4465.1 4491.6 5552.7 4864.9 4319.8 2859.0 4063.1 3803.5 True False 2672.156153267556 3713.4554429148584 4571.564917986051 4239.950213963674 4464.688295390469 4609.77607983301 3910.597271356344 2783.9542793608985 4122.515150869996 4493.044441510565 0.5947317432651913 0.8264898091384986 1.017476007081089 0.9436697698316556 0.9936888792244924 1.025980521635615 0.8703669243123708 0.6196142316422161 0.9175326895907586 1.0 12.133477616550104 -4.8224725760962315 3.3765805473240906 0.9154131905882524 0.5674075608235927 0.43615018330155086 0.11266578624225713 0.29606269415301695 5.5313565322084495 0.03137884213426695 0.25236894996130294 1.5049685483534523e-05 4.8224725760962315 -0.34800562976465976 HEVSASTQS(ph)TPASSR ddPTM_PC-9_Lapatinib_30min_R1 1 HEVSASTQSTPASSR 15 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 HEVS(0.012)AS(0.019)T(0.019)QS(0.455)T(0.455)PAS(0.009)S(0.032)R 56.817 0.036857 2408200.0 2624.0 3415.7 3783.4 3668.3 4405.9 3836.1 3868.1 4576.0 4793.2 4154.0 True False 2586.5812788173344 3407.7911565099835 3472.3434563463393 3938.079019090073 4146.75362433268 3672.0389453858616 4068.3712912413403 4788.617665509306 4253.339341366357 4872.013365142925 0.53090603103086 0.6994626042882403 0.7127122189748909 0.8083062840642569 0.8511375715840286 0.7537005074037063 0.835049287908099 0.9828827030257598 0.8730147112889912 1.0 12.25030237558264 -3.7728467239056878 0.2381554254701903 0.989560085070387 5.3707971741057245e-17 0.8306988959467791 0.054392330770921336 7.336290800905433 0.24310294744663394 0.0839535484012183 2.3082052675363736 0.0001687148367707248 3.7728467239056878 -0.989560085070387 HEVSASTQST(ph)PASSR ddPTM_PC-9_AZD4547_30min_R2 1 HEVSASTQSTPASSR 15 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 HEVSASTQS(0.265)T(0.734)PAS(0.001)S(0.001)R 115.2 0.00034346 3127400.0 1525.1 729.38 4030.2 5129.9 4504.9 5884.4 5181.3 7541.8 5898.2 5501.2 True False 2010.0500759493468 965.1378211967085 3976.7569147140975 3947.280811164933 3879.472395234267 5516.44753777653 5642.425662491903 6376.388103323085 6209.966810586045 5308.604662434962 0.37864000123666636 0.18180630929748254 0.7491152887791103 0.7435627744324035 0.730789471419185 1.0391520726363968 1.0628830024618603 1.2011420154233805 1.16979266784158 1.0 12.37411699105472 -5.721139520941675 0.5908400857486641 1.1519569128019052 0.10465515308293359 0.8530117359174353 0.12290257599165347 0.5177572776698431 0.2834858247386196 0.07722952941466656 0.3256453210857433 1.900467639811486e-06 5.721139520941675 -1.0473017597189715 down HEVSASTQST(ph)PASSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HEVSASTQSTPASSR 15 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 HEVSASTQS(0.063)T(0.93)PAS(0.002)S(0.005)R 139.81 0.00013601 2957700.0 5281.5 10671.0 18868.0 16253.0 18622.0 14063.0 15728.0 11083.0 11218.0 11049.0 True False 6175.553635620097 11730.346357817836 19317.884677288475 15342.397102936957 14973.152779145523 13325.511523503392 14238.129979140831 10792.082993409173 11382.042027629055 13052.096236164127 0.4731464987600357 0.8987327510898939 1.4800599327304529 1.1754737955752252 1.1471837556375521 1.020947998114027 1.090869215298191 0.826846722406703 0.872047050656295 1.0 13.671993909459692 -7.755323919229415 24.940026340660175 0.8870851576514386 1.0608323233849668 0.061796321853402336 0.24230136361040072 371.24780414253405 1514038.61259512 0.12486919869407404 0.06973461068629301 1.756612952678066e-08 7.755323919229415 0.17374716573352822 HEVSASTQSTPASS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 HEVSASTQSTPASSR 15 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 HEVSAST(0.001)QS(0.209)T(0.209)PAS(0.205)S(0.376)R 106.31 0.0016460000000000001 0.0 4423.1 4765.3 4307.1 4412.9 4483.7 4030.3 3620.2 5839.2 4266.8 3265.5 True False 4360.0257829028005 4754.26624062916 3952.986863886801 4737.439387002858 4219.977581293364 3857.933464088175 3807.6362422253587 6110.510549047631 3786.2280526041045 3829.9373239947595 1.1384065623181374 1.2413430921815434 1.0321283429682073 1.2369495859168635 1.1018398538417278 1.0073098167737675 0.9941771679578976 1.5954596726074235 0.9885874708401065 1.0 11.903105067647356 -9.690864819509754 9.109559673173257 1.0000002686412603 1.1534650655433063 0.06106304597477685 0.17366190685454572 0.0 0.0 0.16389989519424078 0.039751563524324664 2.037676235446252e-10 9.690864819509754 0.15346479690204595 HFAAAS(ph)GKVSPTASR ddPTM_PC-9_Lapatinib_30min_R1 1 HFAAASGKVSPTASR 15 1 P21580;A0A087WU80 P21580 TNFAIP3 Tumor necrosis factor alpha-induced protein 3;A20p50;A20p37 1 HFAAAS(0.85)GKVS(0.089)PT(0.057)AS(0.004)R 77.027 0.0062954 10601000.0 54720.0 33051.0 41644.0 32713.0 33652.0 36057.0 31483.0 21767.0 54488.0 34867.0 True False 53939.68276558101 32974.4724401474 38220.19107048872 35118.82314736895 31672.655522377576 34514.9261629723 33113.035692497906 22778.37428434027 48350.987655923025 40893.71449264286 1.3190213565775553 0.8063457391741657 0.9346226319784394 0.8587829103586846 0.7745115824114184 0.8440154334520489 0.8097341144799951 0.557014068468598 1.1823574418660794 1.0 15.319591492468184 -4.758496482406065 24.98927275613084 0.8462759963921758 1.3190220001433692 0.4385761742490767 0.1537207961872356 70.35569578310277 597309.2333551816 0.035799638862598064 0.24407451076663547 1.7438274816428343e-05 4.758496482406065 0.47274600375119347 HFAAASGKVS(ph)PTASR ddPTM_PC-9_AZD4547_30min_R2 1 HFAAASGKVSPTASR 15 1 P21580;A0A087WU80 P21580 TNFAIP3 Tumor necrosis factor alpha-induced protein 3;A20p50;A20p37 1 HFAAAS(0.066)GKVS(0.694)PT(0.204)AS(0.036)R 52.19 0.041317 15262000.0 33882.0 18026.0 43647.0 86881.0 60920.0 47001.0 35152.0 54052.0 32973.0 42870.0 True False 44655.771210619525 23852.55198235743 43068.212261556815 66851.92774806931 52462.3095557441 44062.020039941955 38280.459901552735 45699.50539139453 34715.88546428633 41369.134348612475 1.0794465949978787 0.5765784650303529 1.0410711497762177 1.6159856569566227 1.2681510111778225 1.065094078803701 0.92533867348947 1.1046763755385975 0.8391736015489215 1.0 15.336267148966101 -7.010073363851159 23.159847063078423 0.978762455139242 1.1155289201826537 0.07435631020995825 0.2469227474693828 665.3613244636817 1529746.188769438 0.10176009321385447 0.08448764200997584 9.770721536251063e-08 7.010073363851159 0.13676646504341172 HFAAASGKVSPT(ph)ASR ddPTM_PC-9_Lapatinib_30min_R1 1 HFAAASGKVSPTASR 15 1 P21580;A0A087WU80 P21580 TNFAIP3 Tumor necrosis factor alpha-induced protein 3;A20p50;A20p37 1 HFAAAS(0.024)GKVS(0.298)PT(0.667)AS(0.01)R 69.422 0.018588 8290900.0 42545.0 25129.0 41240.0 31010.0 27930.0 33290.0 28718.0 23216.0 43360.0 26292.0 True False 41938.30049820256 25070.815344421157 37849.40639100361 33290.5788463275 26287.21231249274 31866.26430278024 30204.87752174681 24294.70011417484 38476.34019895799 30836.53716811213 1.3600197800929053 0.813023044959365 1.227420776355636 1.0795822716680743 0.852469658612517 1.03339308590502 0.9795158696671521 0.7878543554267124 1.2477516521779277 1.0 14.912353144449371 -4.741264420400179 24.956727661110712 1.0007271435426055 1.3600210732785958 0.3408017413403447 0.14922289850370324 1669.338436332853 2064887.8317774741 0.035520788009587835 1.4516819836822907 1.814410621641957e-05 4.741264420400179 0.3592939297359903 HFDADGNGYIEGK ddPTM_PC-9_AZD4547_30min_R2 2 HFDADGNGYIEGK 13 0 P22676;A6NER6;H3BN14 P22676 CALB2 Calretinin 0 ; 105.0 0.0010719000000000002 10362300.0 142007.0 139646.0 172761.0 228518.0 228963.0 184856.0 159712.0 196899.0 175489.0 174664.0 False True 187162.27207090662 184783.83857363174 170470.076259968 175836.7056679053 197175.43963906477 173296.92509741307 173926.05859685916 166472.78383889954 184764.99027210593 168549.0665235841 1.1104319705307777 1.0963207473342844 1.0113973323970624 1.043237493358063 1.1698399979656675 1.0281689995189895 1.0319016425553604 0.9876814346854064 1.0962089205415613 1.0 17.362809111693522 -1.522878746141424 0.07566892451645849 0.9460630208479934 1.3338659212408073 0.18768300784945324 0.04973666319422876 391.3766373847933 2.1797474823961966 1.7971752374523378 15.978042711101239 0.02999999994051826 1.522878746141424 0.38780290039281384 HFDETVNR ddPTM_PC-9_AZD4547_30min_R2 2 HFDETVNR 8 0 B7Z4L4;P04843 B7Z4L4 RPN1 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 0 ; 174.52 1.9366e-05 6429100.0 15174.8 16010.3 23105.0 23497.0 20828.8 15452.9 18165.4 20142.7 16941.2 17748.9 False True 20000.07074455194 21185.316376519313 22798.612603461184 18080.129675031174 17937.080651258748 14486.627720159562 19782.08540895729 17030.10854819882 17836.677245854717 17127.51641334471 1.1677157541048457 1.2369170091708692 1.3311102469998455 1.0556188789253909 1.047266878534898 0.8458101788110078 1.1549885535969653 0.9943127851817444 1.0414047673577163 1.0 14.064028347204841 -5.87679764562861 5.776914423978336 1.015864863276944 1.2432327453458945 0.6256106535097988 0.08028719960177641 0.1329208794469674 6.198398491849865 0.022606934379852263 0.03401917843353344 1.3280130855696936e-06 5.87679764562861 0.22736788206895042 HFDETVNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HFDETVNR 8 0 B7Z4L4;P04843 B7Z4L4 RPN1 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 0 ; 167.23 1.9366e-05 3715200.0 12546.5 12734.900000000001 16583.7 13333.3 22198.0 13717.6 11812.8 9910.6 11720.099999999999 8916.3 False True 14670.374645329457 13999.136709977935 16979.118302032482 12586.278428141835 17848.461249676307 12998.224907545336 10693.80606673415 9650.457251148684 11891.484290249171 10532.754608608037 1.3928336119536948 1.3291049901169205 1.6120301794704368 1.1949655048315213 1.6945672725622423 1.2340764966576132 1.015290535487696 0.916232990300725 1.1290004117755381 1.0 13.362595170183678 -7.059517229994262 4.007893349175023 1.012923415654651 1.436840123998476 0.6745955158304299 0.13999036528748152 0.13054097257729452 4.192647136825103 0.05186309291151427 0.040736547266746234 8.719323079700762e-08 7.059517229994262 0.4239167083438251 HFDETVNR ddPTM_PC-9_Lapatinib_30min_R1 2 HFDETVNR 8 0 B7Z4L4;P04843 B7Z4L4 RPN1 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 0 ; 190.52 1.9366e-05 6731100.0 23952.0 27761.0 11973.5 12595.400000000001 14775.2 12122.2 14072.0 16777.0 22241.0 7912.700000000001 False True 23610.440087741146 27696.72111013076 10989.085049046595 13521.707733022677 13906.15178516085 11603.76176422839 14800.57930517519 17556.52066744965 19735.984371887083 9280.399651989996 2.544118892840823 2.9844319370655286 1.1841176523782795 1.4570178268263714 1.4984432035940343 1.2503515149522892 1.5948213288423956 1.8917849797217523 2.1266308684944506 1.0 13.17997121970556 -5.258038361717153 24.974147192959418 1.5250685974880327 2.764275510677843 0.7043198263581953 0.32724846492553866 155.26674784122036 1140131.868427998 0.08669026212876088 0.2108499912944595 5.520286758169882e-06 5.258038361717153 1.2392069131898105 HFEASCGQLS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 3 HFEASCGQLSPAR 13 0 A0A1B0GV70;Q96N21;Q96N21-2 A0A1B0GV70 ENTHD2 AP-4 complex accessory subunit tepsin 1 HFEASCGQLS(1)PAR;HFEAS(0.001)CGQLS(0.999)PAR;HFEASCGQLS(1)PAR 109.67 0.0004315 7931700.0 22812.8 19498.1 32727.0 49500.1 31899.6 35048.6 28417.4 33802.1 27643.6 36352.5 True False 30066.79586428253 25800.479518872908 32293.018596558068 38088.616713921365 27470.89116717687 32857.00550141296 30946.493548201677 28578.762139984763 29104.784260472068 35079.81003983985 0.8570968836529022 0.735479453553811 0.9205585366592108 1.085770324031528 0.7830969191674186 0.9366357874828151 0.8821739203563531 0.8146783607872476 0.8296733713044057 1.0 15.098353315036684 -5.276516111100478 24.44129152443724 0.9021470389789935 0.7962881643163419 0.1949967498490104 0.08927017087898367 892.3586974119212 1446626.7076530221 0.023660108135847333 0.04959257326750083 5.290343711623651e-06 5.276516111100478 -0.10585887466265165 HFEASCGQLS(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HFEASCGQLSPAR 13 0 A0A1B0GV70;Q96N21;Q96N21-2 A0A1B0GV70 ENTHD2 AP-4 complex accessory subunit tepsin 1 HFEASCGQLS(1)PAR;HFEASCGQLS(1)PAR 109.04 0.00047078 7012000.0 27581.0 28482.0 36473.0 37192.0 43273.0 42429.0 40061.0 40204.0 34864.0 32901.0 True False 32249.918550418963 31309.50472901955 37342.65464462277 35108.25281809088 34793.96628782967 40203.9485480143 36266.13206347666 39148.68759965914 35373.82004379207 38865.69085582732 0.8297786001038903 0.8055820966919764 0.9608128357513503 0.9033224945962057 0.8952360172085516 1.0344328805874379 0.9331143037700332 1.0072814026355945 0.9101554421098963 1.0 15.246209540595448 -4.945626149367949 0.6289026133287894 0.9721821686287608 0.7219006778267741 0.5507446399440659 0.047647697165322474 2.1426007066707466 0.7386920925408101 0.022966476116406613 0.3761910396645611 1.133375579075394e-05 4.945626149367949 -0.2502814908019867 HFEASCGQLS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 5 HFEASCGQLSPAR 13 0 A0A1B0GV70;Q96N21;Q96N21-2 A0A1B0GV70 ENTHD2 AP-4 complex accessory subunit tepsin 1 HFEASCGQLS(1)PAR;HFEASCGQLS(1)PAR;HFEAS(0.006)CGQLS(0.994)PAR;HFEASCGQLS(1)PAR;HFEASCGQLS(1)PAR 122.5 0.00010249 14027700.0 89218.3 94270.0 115028.0 89928.0 112278.0 102225.0 96914.0 93151.0 117421.0 83845.6 True False 87946.03068136766 94051.72360693145 105570.8418609204 96541.6051110138 105674.02878704108 97853.07504811388 101931.73271615617 97479.13552444418 104195.81048205361 98338.2002427609 0.8943221501335311 0.956410869578173 1.0735486474259723 0.981730445266316 1.0745979540623147 0.9950667676096429 1.0365425893958213 0.9912641809978625 1.0595659695299733 1.0 16.585464331163095 -5.007485424721012 4.075343350223659 1.025515406541472 0.9019592038580081 0.6248392619540704 0.032962968603540935 0.11450840057624974 4.438231899393251 0.007666215471546016 0.029904306493005756 9.829118597746209e-06 5.007485424721012 -0.1235562026834639 HFELGGDK ddPTM_PC-9_AZD4547_30min_R2 3 HFELGGDK 8 0 H0Y5B4;H7BZ11;J3KQN4;P83881;R4GN19;Q969Q0 H0Y5B4 RPL36A;RPL36A-HNRNPH2;RPL36AL 60S ribosomal protein L36a;60S ribosomal protein L36a-like 0 ;; 102.07 0.0036869 6094100.0 153101.0 168079.0 192524.0 180239.0 161778.0 195814.0 182205.0 198727.0 191603.0 168931.0 False True 201783.933301371 222407.24978601202 189971.00596705324 138687.68321479112 139317.9171915489 183569.71962513967 198420.8920221439 168018.30844216046 201730.7434147228 163016.77710859428 1.2378108368990255 1.3643212295741471 1.1653463486184816 0.8507571163819768 0.8546231845740744 1.126078694972935 1.2171808051999766 1.0306810833969218 1.237484552159555 1.0 17.31466092359144 -5.521850339709126 24.99893840405649 1.0459647423342007 1.2920080069747397 0.4002932253953103 0.1255561688160344 37.85800621523699 920267.0880323357 0.03688239955238034 0.0649557513972338 3.0071123917309824e-06 5.521850339709126 0.24604326464053905 HFELGGDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HFELGGDK 8 0 H0Y5B4;H7BZ11;J3KQN4;P83881;R4GN19;Q969Q0 H0Y5B4 RPL36A;RPL36A-HNRNPH2;RPL36AL 60S ribosomal protein L36a;60S ribosomal protein L36a-like 0 ; 91.087 0.0075435 9631600.0 136015.0 163668.0 151054.0 145796.0 169681.0 124913.0 152823.0 116667.0 113998.0 103679.0 False True 159039.65308129622 179915.87739587054 154655.70023548492 137627.52279700982 136433.22611525023 118362.34238323118 138346.4990972942 113604.6148689042 115665.00508697244 122475.18197748775 1.2985459626467786 1.4689986533675126 1.2627513406259914 1.1237176428307512 1.113966306580611 0.9664189958500119 1.1295880264356233 0.9275725337545198 0.9443954539968179 1.0 16.902129909660957 -5.865066310521531 1.0628331540273301 0.9941297598964083 1.406558918681752 0.8164606544854309 0.07167753687729807 0.2247394404438583 0.5019162901621236 0.027719433405890476 0.068800965195861 1.3643748002742602e-06 5.865066310521531 0.4124291587853437 HFELGGDK ddPTM_PC-9_Lapatinib_30min_R1 2 HFELGGDK 8 0 H0Y5B4;H7BZ11;J3KQN4;P83881;R4GN19;Q969Q0 H0Y5B4 RPL36A;RPL36A-HNRNPH2;RPL36AL 60S ribosomal protein L36a;60S ribosomal protein L36a-like 0 ; 84.213 0.011872 13329200.0 81016.0 115836.0 123763.0 121563.0 134240.0 115428.0 135023.0 134688.0 119062.0 121444.0 False True 79860.6969834851 115567.78885894235 113587.68387899539 130503.14854227992 126344.26712599446 110491.4135158101 142013.83026738695 140946.0961827178 105651.98378155752 142435.43358604188 0.5606799865234597 0.8113696567584118 0.7974678843546311 0.9162267088789114 0.8870283464238755 0.7757298218147722 0.9970400390686476 0.9895437717579986 0.741753516815292 1.0 17.11994856385774 -4.259255681643773 0.9841133534531211 0.8990443350770306 9.850531674576235e-23 0.5707152484644766 0.08654770397855356 3.5459597544633916 1.3496783947248758 0.027588090661552867 4.322598252457275 5.5048351552015375e-05 4.259255681643773 -0.8990443350770306 HFGAEYR ddPTM_PC-9_Lapatinib_30min_R1 1 HFGAEYR 7 0 P04818-2;P04818 P04818-2 TYMS Thymidylate synthase 0 120.65 0.0050066 1752100.0 555.46 1283.5 755.99 1002.8 911.31 576.98 0.0 1284.7 702.88 478.68 False True 547.5390385411112 1280.5281346080044 693.8354204057907 1076.5492572427354 857.7085375043947 552.3039104060726 0.0 1344.3918520279308 623.7142527454698 561.4192001989926 0.9752766530732087 2.280876988450211 1.2358597998783507 1.9175497682679132 1.5277506312580398 0.9837638438626803 0.0 2.3946310556379564 1.1109599609781728 1.0 9.132934593771587 -6.656687183857956 5.572713348594246 1.1184241648182724 1.6347891445279963 0.12928360191842048 0.6329201856985808 0.4564254489112444 20.92754867323334 0.2111232956788889 0.21008546434388073 2.204513771260478e-07 6.656687183857956 0.5163649797097238 HFGAGGNQR ddPTM_PC-9_AZD4547_30min_R2 1 HFGAGGNQR 9 0 Q96QK1 Q96QK1 VPS35 Vacuolar protein sorting-associated protein 35 0 90.37 0.006793899999999999 0.0 610.18 704.48 535.45 580.08 462.83 560.87 421.74 0.0 699.44 0.0 False True 804.2045474675583 932.189383142747 528.3495831431852 446.3515181466607 398.5740435273315 525.7987102360005 459.2740429813623 0.0 736.4109704649397 0.0 0.0 HFGAGGNQR ddPTM_PC-9_Lapatinib_30min_R1 2 HFGAGGNQR 9 0 Q96QK1 Q96QK1 VPS35 Vacuolar protein sorting-associated protein 35 0 ; 98.62899999999999 0.0036935 1035500.0 1464.46 1433.19 1409.02 1712.73 1872.41 462.35 1779.92 3143.3 2467.4 791.46 False True 1443.5765318509273 1429.8715366099304 1293.1758145744889 1838.6898776997898 1762.2785250996963 442.576368290491 1872.0755483845526 3289.349193180815 2189.495429126128 928.262806445841 1.555137749597158 1.5403736169120719 1.393113895757428 1.9807858991354161 1.8984693912784876 0.4767791677284152 2.0167516519943405 3.543553797846505 2.358702098072129 1.0 9.858389503618229 -7.522426383644025 24.99999043953218 2.5267073848146615 1.4933438370915235 0.20842273979510295 0.6960060615666203 20.036241727241723 1107529.731845339 0.3097994743504482 0.18147124754800378 3.003126431445892e-08 7.522426383644025 -1.033363547723138 HFILDECDK ddPTM_PC-9_AZD4547_30min_R2 2 HFILDECDK 9 0 A0A140T9L4;A0A140T973;A0A140T9K1;A0A140T9X9;A0A140T996;F6S4E6;A0A0A0MT12;F6TRA5;F6UJC5;A0A140TA18;F6WLT2;A0A140T9X3;A0A0G2JJZ9;Q5STU3;Q13838;Q13838-2 A0A140T9L4 DDX39B Spliceosome RNA helicase DDX39B 0 ; 106.2 0.0021698 8460100.0 72001.0 78505.0 79887.0 82038.0 81505.0 91740.0 80095.0 96559.0 86306.0 82919.0 False True 94895.8202861641 103880.20600105221 78827.64618276141 63125.40657446515 70189.43762870859 86003.48329746762 87223.29983542518 81638.02525508156 90867.958962809 80016.03104857936 1.185960101277092 1.2982424226713323 0.9851481653083186 0.7889094941005064 0.8771921914759201 1.0748281584380655 1.0900728103155997 1.0202708655408996 1.1356219219076389 1.0 16.288001449515896 -5.268606030517068 24.325335377319405 0.9916930006142337 1.2421012676398178 0.4937286657845045 0.09938277883936324 305.842268120346 1038107.0294678959 0.02903623279297052 0.06260879437411987 5.387582945550198e-06 5.268606030517068 0.25040826702558405 HFILDECDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HFILDECDK 9 0 A0A140T9L4;A0A140T973;A0A140T9K1;A0A140T9X9;A0A140T996;F6S4E6;A0A0A0MT12;F6TRA5;F6UJC5;A0A140TA18;F6WLT2;A0A140T9X3;A0A0G2JJZ9;Q5STU3;Q13838;Q13838-2 A0A140T9L4 DDX39B Spliceosome RNA helicase DDX39B 0 89.24700000000001 0.0079674 4171800.0 33032.0 35094.0 29410.0 32571.0 39909.0 29483.0 38772.0 31592.0 22416.0 27133.0 False True 38623.66518826145 38577.9003918339 30111.245938046104 30746.15246660676 32089.117939153602 27936.85957814481 35099.235475028494 30762.743474490868 22743.79159309438 32051.99811529019 1.2050314320290783 1.2036036022799643 0.9394498848320392 0.9592585259743764 1.001158112630916 0.8716105460151553 1.095071681608662 0.9597761538559342 0.7095904446045941 1.0 14.968126676523445 -5.260398944453939 24.25811084180973 0.9462364602472596 1.2043175576938685 0.5498328145801589 0.09488370186664177 43.15851454063629 1006198.9527932527 0.02435356594053057 0.057324076936650016 5.490362954478561e-06 5.260398944453939 0.2580810974466089 HFILDECDK ddPTM_PC-9_Lapatinib_30min_R1 2 HFILDECDK 9 0 A0A140T9L4;A0A140T973;A0A140T9K1;A0A140T9X9;A0A140T996;F6S4E6;A0A0A0MT12;F6TRA5;F6UJC5;A0A140TA18;F6WLT2;A0A140T9X3;A0A0G2JJZ9;Q5STU3;Q13838;Q13838-2 A0A140T9L4 DDX39B Spliceosome RNA helicase DDX39B 0 ; 104.2 0.002282 12341100.0 86015.0 119599.0 111735.0 112857.0 151925.0 129835.0 118201.0 125978.0 125384.0 122938.0 False True 84788.41032678087 119322.07586364078 102548.57960957273 121156.88025991534 142989.07019604204 124282.25971016752 124320.86941806514 131831.3977852996 111261.93356794621 144187.66949541192 0.5880420331606709 0.8275470175862552 0.7112160142988916 0.8402721306468621 0.9916872274615132 0.8619479054283641 0.862215679420639 0.9143042414559208 0.7716466599211286 1.0 17.137588269262167 -3.9596196464253173 0.6486448581775431 0.8925294810727831 1.8840649136983969e-16 0.5586734655634693 0.07857693291987389 6.730942400967652 0.9760476189541472 0.03383703292823483 5.6738037123499705 0.00010974389085108834 3.9596196464253173 -0.8925294810727828 HFLPLDFSTQVNSSLTS(ph)PTGR ddPTM_PC-9_AZD4547_30min_R2 2 HFLPLDFSTQVNSSLTSPTGR 21 0 P19793 P19793 RXRA Retinoic acid receptor RXR-alpha 1 HFLPLDFSTQVNS(0.002)S(0.005)LT(0.197)S(0.599)PT(0.197)GR;HFLPLDFSTQVNS(0.003)S(0.001)LT(0.152)S(0.422)PT(0.422)GR 169.1 7.6939e-09 50479000.0 47784.0 45481.0 70408.0 134723.0 114778.0 112807.0 80303.0 138870.0 84835.0 101903.0 True False 62978.318031056064 60181.84382057021 69474.34391623006 103664.69379960092 98843.055912495 105753.16045713346 87449.8114324758 117410.83241513623 89319.20490591496 98335.40698685912 0.6404439658186605 0.6120058447372115 0.7065038529358418 1.054194994214586 1.005162422581967 1.0754331903183723 0.8893013626735893 1.1939832865167908 0.9083117428684764 1.0 16.5854233514252 -5.6893246372856465 4.388217497347535 1.023160075790233 0.6345392057964591 0.8087751972015766 0.0817215694406805 0.07808481462646537 2.863305088151747 0.021067294615000152 0.03708193147267322 2.044915480775604e-06 5.6893246372856465 -0.388620869993774 HFLPLDFSTQVNSSLTS(ph)PTGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HFLPLDFSTQVNSSLTSPTGR 21 0 P19793 P19793 RXRA Retinoic acid receptor RXR-alpha 1 HFLPLDFSTQVNS(0.001)S(0.001)LT(0.206)S(0.585)PT(0.206)GR;HFLPLDFSTQVNS(0.016)S(0.027)LT(0.201)S(0.556)PT(0.201)GR 135.12 8.5273e-06 25402000.0 53778.0 57562.0 63566.0 78095.0 112930.0 114345.0 129700.0 100899.0 124983.0 113932.0 True False 62881.55323608394 63276.374945994816 65081.654515397466 73719.59033740626 90802.17717478797 108348.54690713185 117413.8770533168 98250.50816132766 126810.63993039425 134586.96971478406 0.4672187312734819 0.470152311773493 0.4835657913490298 0.5477468620746302 0.674672870391654 0.8050448504542711 0.8724015207574672 0.7300150108850773 0.9422207825849013 1.0 17.03817921397011 -6.55581371496203 0.5270989466521815 0.9498843211672915 0.39332468771343365 0.9105757007638097 0.05736616381018514 0.30700751073349836 0.1807491854965902 0.0510361107612742 0.07923160365615056 2.7809058458025174e-07 6.55581371496203 -0.5565596334538578 down HFLPLDFSTQVNSSLTS(ph)PTGR ddPTM_PC-9_Lapatinib_30min_R1 2 HFLPLDFSTQVNSSLTSPTGR 21 0 P19793 P19793 RXRA Retinoic acid receptor RXR-alpha 1 HFLPLDFSTQVNSS(0.002)LT(0.206)S(0.586)PT(0.206)GR;HFLPLDFSTQVNS(0.003)S(0.031)LT(0.187)S(0.592)PT(0.187)GR 137.41 9.812899999999999e-06 18695900.0 54435.0 39598.0 48346.0 37281.0 74901.0 79967.0 80701.0 71432.0 88456.0 58965.0 True False 53658.746917843586 39506.313263893884 44371.178500956856 40022.769105770225 70495.4704410318 76546.99782218174 84879.30290697426 74750.99149533664 78493.15379702556 69157.02168407627 0.7758973074775828 0.5712552724489348 0.6416004827919524 0.5787231452592421 1.0193537651616902 1.106857929363477 1.227341791766578 1.080887951433403 1.1349990483337857 1.0 16.077588118770606 -6.362256232067027 3.8839661502777982 1.1175187454343256 0.6363752312316142 0.8968551644506765 0.07557353465873959 0.06667873148415289 1.8118157364050747 0.023769954800449272 0.02733325042917614 4.3425394042808284e-07 6.362256232067027 -0.4811435142027114 HFNYPST(ph)PPSER ddPTM_PC-9_Lapatinib_30min_R1 1 HFNYPSTPPSER 12 0 Q9BX63;Q9BX63-2 Q9BX63 BRIP1 Fanconi anemia group J protein 1 HFNYPS(0.314)T(0.59)PPS(0.096)ER 78.902 0.033487 9141300.0 30487.0 35145.0 35112.0 29293.0 32198.0 33228.0 25373.0 35387.0 31445.0 22865.0 True False 30052.24978936893 35063.62391180235 32225.226896239546 31447.304938583413 30304.176943703576 31806.91589825119 26686.689788957523 37031.20920659481 27903.332969470343 26817.184784302608 1.1206340274375095 1.3075057726539134 1.2016633049082217 1.172654967011714 1.1300282705827522 1.1860646877769703 0.9951339040098843 1.3808760876447763 1.0405019465653795 1.0 14.710870173432319 -14.522878745186144 0.15337418300664507 0.3610602091488896 1.2277535630982368 0.2159189653101763 0.10559421892995216 208.42886146905286 1.8712152838596396 40.4786698263831 0.4817844390794482 3.000000000650664e-15 14.522878745186144 0.8666933539493472 HFNYPSTPPS(ph)ER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HFNYPSTPPSER 12 0 Q9BX63;Q9BX63-2 Q9BX63 BRIP1 Fanconi anemia group J protein 1 HFNYPS(0.11)T(0.338)PPS(0.551)ER 60.937 0.032813999999999996 6307300.0 24782.0 25277.0 38125.0 32675.0 34698.0 32683.0 35521.0 32178.0 29929.0 25821.0 True False 28977.103133188903 27786.33351012666 39034.044589867655 30844.3256837793 27899.17598167713 30969.045944866735 32156.193730230272 31333.36159540922 30366.655004894805 30502.142901076448 0.9500022089322214 0.9109633247815535 1.2797148291010763 1.0112183194411164 0.9146628180242558 1.0153072210468796 1.054227364763131 1.0272511573048673 0.9955580859803506 1.0 14.896622981049774 -5.974203700358901 24.999978162930546 1.0019855855569668 1.0519946703105691 0.042301038400533675 0.09662521044795415 808.7973293581236 783824.1331150216 0.028411146416564507 0.042138844375550044 1.0611976990307148e-06 5.974203700358901 0.05000908475360233 HFPNIDR ddPTM_PC-9_AZD4547_30min_R2 2 HFPNIDR 7 0 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ; 114.78 0.0071446 11068200.0 6224.3 6482.5 8843.6 9557.2 12279.0 8871.1 7176.7 7838.4 8063.1 7409.4 False True 8203.497926517299 8577.841352803285 8726.328085694413 7353.935197268079 10574.272800968192 8316.388714630099 7815.4123968898975 6627.155388513036 8489.299004855098 7149.999161245836 1.147342501937846 1.1996982320356886 1.2204656097014022 1.0285225258665216 1.4789194463521729 1.163131425204395 1.0930647991192377 0.9268749882424184 1.1873146854154175 1.0 12.803727357313038 -7.284572299721538 3.592490547369799 1.040414159396028 1.2126199750242854 0.28630409141540825 0.1215990063628355 0.3047765345372583 8.494709756847035 0.052008020678690016 0.03544796177869345 5.193112133213125e-08 7.284572299721538 0.17220581562825732 HFPNIDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HFPNIDR 7 0 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ; 110.81 0.007898100000000002 6356000.0 6872.799999999999 8030.200000000001 8533.7 9324.0 12144.8 9185.0 9467.5 8204.6 9010.4 7286.6 False True 8036.229296012455 8827.385186257035 8737.175772237475 8801.606508815863 9765.113622176274 8703.322430731607 8570.669861235743 7989.237943492275 9142.160053997934 8607.602899306139 0.9336198927880673 1.0255335067755755 1.015053305135833 1.022538633784484 1.1344753860524213 1.0111203470403105 0.9957092539581057 0.9281606083543061 1.0621029061104672 1.0 13.071395807210846 -10.496226432865349 14.797925912342833 0.9999999998047049 1.0152215459146985 0.005561256607216625 0.055870592398460574 0.0 0.0 0.055566453834267386 0.013476844611746584 3.1898742818082025e-11 10.496226432865349 0.0152215461099936 HFPNIDR ddPTM_PC-9_Lapatinib_30min_R1 3 HFPNIDR 7 0 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ;; 107.59 0.0018252 9092600.0 10962.9 13216.2 12814.0 9266.2 11267.29 11568.5 9940.3 10378.8 10451.0 7604.1 False True 10806.567035650367 13185.598700900906 11760.482383470426 9947.667259137044 10604.57015454445 11073.742222490648 10454.96009573856 10861.036937672201 9273.898326091092 8918.458553173652 1.2117079393506658 1.4784616222955684 1.3186676053212618 1.1154020843206303 1.1890586351125432 1.241665491459848 1.1722833080855817 1.2178154860412822 1.0398543953305648 1.0 13.12257866410557 -4.215219080008655 0.10465570260619077 0.8494090335822834 1.8739239484021322 0.5246513384025497 0.08922573812672412 50.30625129823009 0.7187225015206464 1.3865430859688572 7.676150198188212 6.0922949367308085e-05 4.215219080008655 1.0245149148198487 HFQQQEQER ddPTM_PC-9_AZD4547_30min_R2 1 HFQQQEQER 9 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 0 83.99799999999999 0.01137 2905500.0 2968.6 1182.5 2822.3 6211.9 3882.2 4245.9 3545.7 4781.4 2895.8 3320.4 False True 3912.5530492841326 1564.7199999521613 2784.874457941938 4779.842427898294 3343.223541649865 3980.4032017954846 3861.2604310689458 4042.5444956414876 3048.866076107129 3204.153806651105 1.2210877771106212 0.48834110169872413 0.8691450616887252 1.4917643522531325 1.0434029523520634 1.2422634623634672 1.2050796135484616 1.2616574420522735 0.9515354942632176 1.0 11.645727686705515 -5.555060942989758 22.577021626426337 1.1807860818969866 0.8107216728662571 0.2914036288839291 0.22001373693877851 64.36902477234533 45156.665931955955 0.0557680286919396 0.09659534767195052 2.7857302296513892e-06 5.555060942989758 -0.37006440903072957 HFQQQEQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HFQQQEQER 9 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 0 ; 94.69200000000001 0.0047553000000000005 978510.0 5971.2 6271.9 8611.1 5836.4 9154.8 6759.5 5541.5 4234.77 7194.6 5264.5 False True 6982.006223424158 6894.532782456916 8816.42128177861 5509.4054298641 7360.982658281676 6405.019920580324 5016.569003014301 4123.611774609703 7299.807414154041 6218.912176240927 1.1227053905180713 1.1086396763725281 1.4176790139377349 0.8859114381631783 1.1836447355542306 1.0299260930312562 0.8066634261502963 0.663076058601338 1.1738077669021643 1.0 12.6024465281698 -7.023191698489147 4.265564445945057 0.8843413810366024 1.1413653646205593 0.2827387083013122 0.1724642674065894 0.25401515391423807 10.805671891502964 0.06509731295044202 0.05252063105116854 9.479999217945465e-08 7.023191698489147 0.25702398358395684 HFQQQEQER ddPTM_PC-9_Lapatinib_30min_R1 1 HFQQQEQER 9 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 0 101.46 0.0029303000000000003 1506400.0 3679.6 3356.1 4039.2 3946.3 2481.7 2919.1 2914.9 1000.3 2325.6 2137.6 False True 3627.1282292440014 3348.3291566481685 3707.1125677628925 4236.524066470885 2335.7312852099244 2794.256897754456 3065.8192592847636 1046.7775897746853 2063.666438346325 2507.08131182704 1.4467533271191453 1.3355486879713796 1.4786566954469171 1.68982316069498 0.9316535822716321 1.114545780614565 1.2228639114423228 0.41752837645774016 0.8231350250233506 1.0 11.291793072324683 -6.875768606166648 0.9915827796159653 0.7708035548268241 1.4666719361291434 0.568845513364809 0.23139397734461525 0.3862250887435528 0.8038042823282103 0.14369338142896135 0.11672503671758691 1.33116347828052e-07 6.875768606166648 0.6958683813023193 HFS(ph)ESTSIDNALSR ddPTM_PC-9_AZD4547_30min_R2 2 HFSESTSIDNALSR 14 0 Q8NEV8-2;Q8NEV8 Q8NEV8-2 EXPH5 Exophilin-5 1 HFS(0.831)ES(0.168)T(0.001)SIDNALSR;HFS(0.963)ES(0.036)T(0.001)SIDNALSR 95.9 0.0017472999999999998 28118000.0 26310.0 28912.0 35665.0 47264.0 52484.0 34299.0 28068.0 36877.0 34213.0 37573.0 True False 34676.03271800364 38257.238595024835 35192.05879690295 36368.01502152077 45197.50253978454 32154.27810791194 30565.997625079162 31178.5069991574 36021.429332776155 36257.58070633112 0.9563802118752143 1.0551514428083324 0.9706124377669215 1.003045826915042 1.246566970528521 0.8868291121888703 0.8430236389087559 0.8599169164564021 0.9934868414010389 1.0 15.145995043753928 HFS(ph)ESTSIDNALSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HFSESTSIDNALSR 14 0 Q8NEV8-2;Q8NEV8 Q8NEV8-2 EXPH5 Exophilin-5 1 HFS(0.767)ES(0.232)T(0.001)SIDNALSR;HFS(0.99)ES(0.009)TSIDNALSR 99.663 0.0012183 5784900.0 7605.799999999999 11323.599999999999 15411.6 16910.4 19918.3 21549.8 19421.9 19151.1 20733.9 13736.7 True False 8893.311718602536 12447.732172934693 15779.070992818473 15962.965112256512 16015.452099712938 20419.69055174523 17582.117029620753 18648.403917267733 21037.094062814947 16227.054970342624 0.5480545752051987 0.7670974305371363 0.9723927737754688 0.9837253365710059 0.9869598722000744 1.2583731668540763 1.083506345529408 1.149216783412054 1.296420952616688 1.0 13.98611357011853 -4.551951924018373 0.5990997002723272 1.1606583069518055 3.8862039108197906e-19 0.8135403256303457 0.09092103976657318 1.8706697001481607 0.4185220613803919 0.044534168350605016 1.5943484169272693 2.8057442139482784e-05 4.551951924018373 -1.1606583069518055 HFS(ph)ESTSIDNALSR ddPTM_PC-9_Lapatinib_30min_R1 2 HFSESTSIDNALSR 14 0 Q8NEV8-2;Q8NEV8 Q8NEV8-2 EXPH5 Exophilin-5 1 HFS(0.997)ES(0.002)TSIDNALSR;HFS(0.966)ES(0.032)T(0.002)SIDNALSR 73.953 0.010934000000000001 20583000.0 14193.5 16403.4 20444.3 17315.9 19405.3 25551.0 20913.0 21942.1 22358.2 21538.0 True False 13991.098087230874 16365.418935121885 18763.448571280198 18589.369050149053 18263.9184062877 24458.243292290113 21995.772811905103 22961.61006957426 19839.984073716387 25260.814602418977 0.5538656732744908 0.6478579251183266 0.7427887368875036 0.7358974499725331 0.7230138336290527 0.9682286053414917 0.8707467735343256 0.9089813781134143 0.7854055534621005 1.0 14.624613542978986 -3.8952570555148966 0.2843625033209449 0.9512333848038206 4.227768753386066e-18 0.7602289217283438 0.0660656268348636 6.946119430285291 0.3117388742455759 0.078458593240587 2.5133725365502193 0.00012727495275137877 3.8952570555148966 -0.9512333848038206 HFS(ph)GLEEAVYR ddPTM_PC-9_AZD4547_30min_R2 1 HFSGLEEAVYR 11 0 P50990-2;P50990;H7C4C8 P50990-2 CCT8 T-complex protein 1 subunit theta 1 HFS(1)GLEEAVYR 75.462 0.022349 0.0 3676.1 3096.8 5545.5 7866.4 8224.4 6381.4 3711.0 5983.9 4461.2 5313.4 True False 4845.02333236994 4097.780038775353 5471.963046634671 6052.923014668477 7082.584023477705 5982.370049209288 4041.2718108404156 5059.225751342519 4697.009924279691 5127.379483273093 0.944931684533147 0.799195778690348 1.0672046148496914 1.1805100508777941 1.3813262791613186 1.1667500072357442 0.7881748998731504 0.9867078822324523 0.91606442230434 1.0 12.324005961873779 -7.248628416229153 24.679322849907912 0.9216291165901396 1.093090543806339 0.223248548467882 0.1527616604138092 1157.0987855467406 2229063.782664816 0.06746900064994549 0.05190495405321383 5.64120112403251e-08 7.248628416229153 0.1714614272161994 HFS(ph)GLEEAVYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HFSGLEEAVYR 11 0 P50990-2;P50990;H7C4C8 P50990-2 CCT8 T-complex protein 1 subunit theta 1 HFS(1)GLEEAVYR 108.97 0.0015368 0.0 3810.2 4056.8 5511.1 3436.5 5049.7 5188.2 4712.8 4303.7 4386.2 3197.8 True False 4455.191605119699 4459.532293542821 5642.5055249631405 3243.9640462833217 4060.2475345747594 4916.121658695885 4266.3694662827365 4190.732435147076 4450.339877124849 3777.5358262291265 1.1793909601559047 1.1805400395089007 1.4937000691786144 0.8587513647809832 1.07484024542736 1.3014096715009416 1.1294054279139905 1.1093825784652895 1.1781065969577686 1.0 11.883229722667147 -14.522878742621035 0.08916067778062826 0.4942663891807338 1.2980577399080042 0.10694896372188323 0.15199357332523927 545.0373172081709 3.3695502211344084 53.30705507420474 3.8043298562577155 3.0000000183698093e-15 14.522878742621035 0.8037913507272705 HFS(ph)GLEEAVYR ddPTM_PC-9_Lapatinib_30min_R1 1 HFSGLEEAVYR 11 0 P50990-2;P50990;H7C4C8 P50990-2 CCT8 T-complex protein 1 subunit theta 1 HFS(1)GLEEAVYR 88.09200000000001 0.010659 0.0 4456.8 4207.5 6015.8 4067.8 5525.5 6768.1 5897.4 3723.5 6536.1 4616.9 True False 4393.245214722977 4197.7577922580285 5521.20414565954 4366.959581783004 5200.5009535509735 6478.644140211686 6202.738515800183 3896.5074033050514 5799.935589815707 5414.925013367447 0.8113215240982432 0.7752199304506189 1.0196270736953381 0.8064672310332269 0.9604012873147569 1.1964420789241421 1.145489272794714 0.7195865859058096 1.0711017374197818 1.0 12.402725643993016 -5.258421892690627 24.61102910620119 0.9852047256330697 0.7932707047654783 0.2522231502864014 0.13522626173997312 307.8974893817417 2511212.995863358 0.036454343622987384 0.08819919657204052 5.515413874783126e-06 5.258421892690627 -0.19193402086759137 HFSQS(ph)EETGNEVFGALNEEQPLPR ddPTM_PC-9_AZD4547_30min_R2 2 HFSQSEETGNEVFGALNEEQPLPR 24 0 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 HFS(0.453)QS(0.547)EETGNEVFGALNEEQPLPR;HFS(0.303)QS(0.69)EET(0.008)GNEVFGALNEEQPLPR 92.07 5.6453e-06 23133700.0 13344.1 6901.700000000001 14980.9 23326.9 18953.1 16511.2 9203.0 19019.8 11795.8 17766.6 True False 17587.24622547747 9132.53955490049 14782.243477653821 17949.243602012382 16321.789219319993 15478.752053860344 10022.049171426665 16080.72694152382 12419.301906397013 17144.596741732155 1.0258185999013816 0.5326774197418545 0.8622100420520208 1.046932970917981 0.9520077646148806 0.9028355864552398 0.5845602158160832 0.9379472252258498 0.7243857696674098 1.0 14.065466350574518 -10.036095134620503 18.222189777678402 0.999999999872778 0.839038175938121 0.07575213011199355 0.16643931774343113 0.0 0.0 0.16096684445851964 0.03904019423087326 9.202479642401316e-11 10.036095134620503 -0.16096182393465697 HFSQS(ph)EETGNEVFGALNEEQPLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HFSQSEETGNEVFGALNEEQPLPR 24 0 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 HFS(0.164)QS(0.836)EETGNEVFGALNEEQPLPR;HFS(0.11)QS(0.857)EET(0.033)GNEVFGALNEEQPLPR 120.26 5.7006e-09 14460500.0 7263.9 5711.4 5076.4 8858.4 11212.5 12276.1 11831.5 9518.599999999999 10885.0 7952.0 True False 8493.534801435346 6278.390046672366 5197.44062835421 8362.09256732029 9015.491114604725 11632.31970516106 10710.734667357876 9268.746835790354 11044.172532603157 9393.63465200264 0.9041798107002809 0.6683664288917037 0.5532938868605202 0.8901871189484216 0.9597447046423827 1.2383193658357952 1.1402119695036725 0.9867050592407636 1.1757081195667576 1.0 13.197467768401085 -6.2155710844837335 2.2769483675624405 1.1049826973474868 0.709263072482811 0.6842580200653019 0.11468144183178326 0.1705102162008093 1.7360621616133625 0.037992556279282066 0.05025759137560268 6.087359008878049e-07 6.2155710844837335 -0.3957196248646758 HFSQS(ph)EETGNEVFGALNEEQPLPR ddPTM_PC-9_Lapatinib_30min_R1 2 HFSQSEETGNEVFGALNEEQPLPR 24 0 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 HFS(0.441)QS(0.557)EET(0.002)GNEVFGALNEEQPLPR;HFS(0.223)QS(0.77)EET(0.007)GNEVFGALNEEQPLPR 122.0 3.6363e-09 23257000.0 13108.2 14758.7 17863.2 16739.3 20281.0 19010.6 16926.7 19867.3 23498.4 15338.96 True False 12921.274664250534 14724.527136921826 16394.556649946055 17970.363962667852 19088.111453980127 18197.560953873068 17803.08170302081 20790.40728714446 20851.762742878083 17990.278798120555 0.7182364881193737 0.8184713145446139 0.9113008660910132 0.9988930224108153 1.0610236599543006 1.011521897913787 0.989594541741104 1.1556467534742394 1.1590572317898968 1.0 14.134929923979271 -4.6275608664176024 0.5482881246682303 1.0881542754806643 0.3900925348608417 0.8288516486745 0.05403438865971652 1.9302665258313252 0.3917517609819952 0.032069357672811785 0.8942846721217822 2.357431778494518e-05 4.6275608664176024 -0.6980617406198226 HFVALSTNTTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HFVALSTNTTK 11 0 P06744-2;P06744;A0A2U3TZU2;K7EQ48;A0A0J9YXP8;A0A2R8Y6C7;A0A0J9YYH3;A0A0J9YX90 P06744-2 GPI Glucose-6-phosphate isomerase 0 ; 145.28 0.00016719 6363100.0 93604.0 89655.0 97899.0 114499.0 128798.0 117757.0 124013.0 100677.0 117376.0 97799.0 False True 109449.30843672862 98555.35589074691 100233.28344402523 108083.99224076659 103560.95648417897 111581.61562064907 112265.5908636312 98034.33542609894 119092.40194642455 115529.18452354196 0.9473736778123417 0.8530775690766154 0.8676014104782346 0.9355557445204832 0.8964051543450117 0.9658305481928813 0.9717509158108381 0.848567708933512 1.0308425740004812 1.0 16.817897820007303 -7.767829666073578 0.33082943857206876 1.008123556322716 0.8806776148776365 0.3082373745729797 0.04988288325274301 1.7569352717702682 0.6156816263234137 0.07516647543521528 0.07608593260092807 1.7067516600168784e-08 7.767829666073578 -0.12744594144507948 HFVALSTNTTK ddPTM_PC-9_Lapatinib_30min_R1 2 HFVALSTNTTK 11 0 P06744-2;P06744;A0A2U3TZU2;K7EQ48;A0A0J9YXP8;A0A2R8Y6C7;A0A0J9YYH3;A0A0J9YX90 P06744-2 GPI Glucose-6-phosphate isomerase 0 ; 147.74 0.0002221 24280300.0 198175.0 156064.0 174433.0 161496.0 202159.0 170035.0 164001.0 168244.0 188255.0 158699.0 False True 195348.98815915594 155702.64339654322 160091.79207085163 173372.95457486343 190268.40507988635 162762.99942094443 172492.169316944 176061.23044491827 167051.73948696587 186129.91069687437 1.049530338395184 0.8365267184279473 0.8601078218512249 0.9314620843353514 1.0222344402762424 0.8744591280979842 0.9267299848322584 0.9459050927695675 0.8975007770729626 1.0 17.505950386613264 -10.965606126957004 2.9227526317142756 1.0017710033195906 0.9244351300374422 0.10341221565492131 0.06388902241782736 18031422.058613107 21240295.986067217 263788.4295153386 0.016806262630855745 1.0824151769614307e-11 10.965606126957004 -0.07733587328214842 HFVDEK ddPTM_PC-9_Lapatinib_30min_R1 1 HFVDEK 6 0 H0Y562;H0Y6E5;A6PVN9;F6WIT2;A6PVN5;Q15257-4;Q15257-3;Q15257-2;Q15257 H0Y562 PPP2R4 Serine/threonine-protein phosphatase 2A activator 0 117.7 0.0003432 0.0 21797.0 19882.0 21270.0 19887.0 21286.0 17152.0 18521.0 21899.0 22982.0 18266.0 False True 21486.170782919755 19835.964450546446 19521.262704574354 21349.556321087217 20033.99932988615 16418.44894326485 19479.926756051 22916.50748622997 20393.52514881117 21423.253762084918 1.0029368564427028 0.9259081123172955 0.9112183854687504 0.9965599324072737 0.9351520339707927 0.7663844682791547 0.9092888957197885 1.0697024710031595 0.9519340701132818 1.0 14.38688999268756 -7.738021703544931 24.857121625803078 1.0081137215214344 0.9183680139915982 0.26154886778406217 0.06622094673173985 290.8185961900959 308695.169383749 0.03290259184148268 0.018982411026925047 1.8280088604717574e-08 7.738021703544931 -0.08974570752983624 HFVGYPTNSDFELK ddPTM_PC-9_AZD4547_30min_R2 1 HFVGYPTNSDFELK 14 0 F2Z3J9;Q14914-2;Q14914;F6XGT7;Q5JVP2 F2Z3J9 PTGR1 Prostaglandin reductase 1 0 102.33 0.0012487 4972500.0 24804.0 23799.0 33182.0 37083.0 33143.0 33723.0 28247.0 34283.0 34158.0 29756.0 False True 32691.156044749605 31491.5613351894 32741.98499926637 28534.087276638762 28541.666539823167 31614.295478967742 30760.928278310188 28985.3500949674 35963.52214506091 28714.251497021523 1.1384993283958873 1.0967223484288267 1.1402694931004083 0.9937256166889306 0.9939895714427291 1.1009966769374795 1.0712773857783116 1.009441255955218 1.2524624627179064 1.0 14.809479334600589 -5.725378697820529 24.997544713883048 1.0600575590336938 1.1223196260515262 0.13819656764191335 0.07415833774104531 372.64800503061167 258320.02797160068 0.019770643577617267 0.034242342174108834 1.8820072936183243e-06 5.725378697820529 0.062262067017832434 HFVGYPTNSDFELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HFVGYPTNSDFELK 14 0 F2Z3J9;Q14914-2;Q14914;F6XGT7;Q5JVP2 F2Z3J9 PTGR1 Prostaglandin reductase 1 0 ; 88.163 0.0048885 9932400.0 77538.0 78214.0 84338.0 98688.0 96291.0 104917.0 106317.0 82311.0 89165.0 88086.0 False True 90663.65195469282 85978.56902168172 86348.93777364602 93158.83131081294 77423.46978072701 99414.96782417718 96245.88409157642 80150.4234657135 90468.86944139277 104055.29451160754 0.8713026317423871 0.8262776961540449 0.829837041727979 0.8952819916378297 0.7440608394231232 0.9554051842416079 0.9249494179350963 0.7702676143670188 0.8694307182158888 1.0 16.66699084817234 -6.780795082609338 24.99995059072723 0.8909609515831999 0.836204240083415 0.20272112751830595 0.06751282115744447 523.2548454869448 675834.4813613708 0.02391501620173369 0.021121957758482163 1.6565514058637178e-07 6.780795082609338 -0.054756711499784894 HFVGYPTNSDFELK ddPTM_PC-9_Lapatinib_30min_R1 2 HFVGYPTNSDFELK 14 0 F2Z3J9;Q14914-2;Q14914;F6XGT7;Q5JVP2 F2Z3J9 PTGR1 Prostaglandin reductase 1 0 ; 108.97 0.00053261 13321600.0 178413.0 143705.0 164909.0 150216.0 151722.0 146512.0 155077.0 137102.0 163413.0 141095.0 False True 175868.79790306286 143372.2599017087 151350.81858714903 161263.38574588645 142798.01025692883 140246.02329615323 163106.12826241154 143472.25943545863 145007.70712482271 165483.08275273052 1.0627599811265962 0.8663862040565171 0.914599946227142 0.9745007348385619 0.862916062968815 0.8474946258144875 0.9856362689721542 0.8669904926163293 0.8762690706064336 1.0 17.3363242130631 -4.752031101947528 24.956461191914045 0.9073911984378042 1.0627602936306157 0.41642980936475915 0.05394645112502484 354.80385550039114 941087.1818002791 0.01297269690424923 0.16129806461830537 1.769982196714534e-05 4.752031101947528 0.1553690951928115 HGAGS(ph)GCLGTMEVK ddPTM_PC-9_AZD4547_30min_R2 4 HGAGSGCLGTMEVK 14 0 Q9BYG5-2;Q9BYG5 Q9BYG5-2 PARD6B Partitioning defective 6 homolog beta 1 HGAGS(0.993)GCLGT(0.007)MEVK;HGAGS(0.984)GCLGT(0.016)MEVK;HGAGS(0.999)GCLGT(0.001)MEVK;HGAGS(1)GCLGTMEVK 103.04 0.00090953 82596300.0 145586.0 118904.0 179144.0 231825.0 201788.0 205627.0 163843.0 186238.0 176590.0 185298.0 True False 191879.31962308186 157337.3927055491 176768.43350938975 178381.3279105459 173773.21931442016 192769.1111838718 178424.7095940517 157459.19642349132 185924.18688436973 178810.7734203217 1.0730858994275505 0.8799100283275652 0.9885782054858008 0.9975983241861701 0.9718274575432879 1.0780620624616333 0.9978409364330498 0.8805912161308073 1.0397817946199857 1.0 17.44807413652758 -4.450386776971506 20.9786678382628 0.9814724249983352 4.112331961025589 0.1804156673099877 0.05851174303732135 373.6400834024995 112487.73272478199 0.014008185728028677 2211.1102973576417 3.54497537748589e-05 4.450386776971506 3.1308595360272538 HGAGS(ph)GCLGTMEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HGAGSGCLGTMEVK 14 0 Q9BYG5-2;Q9BYG5 Q9BYG5-2 PARD6B Partitioning defective 6 homolog beta 1 HGAGS(0.999)GCLGT(0.001)MEVK;HGAGS(0.968)GCLGT(0.032)MEVK;HGAGS(1)GCLGTMEVK;HGAGS(1)GCLGTMEVK 86.49799999999999 0.005704600000000001 88245500.0 120624.0 122863.0 143598.0 173390.0 199567.0 174866.0 176583.0 187603.0 153461.0 145077.0 True False 141043.26076740262 135060.0266667205 147021.9209184476 163675.52043796494 160463.27895369605 165695.7191260003 159855.7798897905 182678.6200318094 155705.0768053117 171378.31167110018 0.8229936413312618 0.7880812067160533 0.8578793867487969 0.9550538737485171 0.9363103031476254 0.9668418221087065 0.9327655193416592 1.065937797207363 0.9085459839523469 1.0 17.38682501898434 -5.668389219445274 2.2002741607230516 0.9696211816303764 0.8037383672222883 0.7237317401727141 0.04146488560465241 0.15190056213785003 1.487973748263489 0.011824583563175462 0.024650393945748094 2.145906427368794e-06 5.668389219445274 -0.16588281440808805 HGAGS(ph)GCLGTMEVK ddPTM_PC-9_Lapatinib_30min_R1 3 HGAGSGCLGTMEVK 14 0 Q9BYG5-2;Q9BYG5 Q9BYG5-2 PARD6B Partitioning defective 6 homolog beta 1 HGAGS(0.998)GCLGT(0.002)MEVK;HGAGS(0.997)GCLGT(0.003)MEVK;HGAGS(1)GCLGTMEVK 79.639 0.011041 48855600.0 145205.0 130463.0 139376.0 129058.0 144932.0 130555.0 118943.0 108724.0 150158.0 115277.0 True False 143134.3500726641 130160.92093912304 127917.04328691868 138549.3558448671 136407.3847072753 124971.46698856956 125101.28654743129 113775.71395647588 133245.62480616075 135202.47585305278 1.0586666343908688 0.9627110755027205 0.9461146512283369 1.0247545762065182 1.0089118845392455 0.9243282432519729 0.9252884295062751 0.8415209354607903 0.9855265146991918 1.0 17.04476204520052 -6.767393274271521 24.51311694545526 0.9248000897860033 0.9965031566124998 0.28561341263116835 0.049775424866358144 134.94367147450893 555580.0431624412 0.017010121169249784 0.015403291198579052 1.7084675159479595e-07 6.767393274271521 0.07170306682649652 HGANVNY(ph)FCR ddPTM_PC-9_AZD4547_30min_R2 1 HGANVNYFCR 10 0 A6NK59-2;A6NK59-3;A6NK59 A6NK59-2 ASB14 Ankyrin repeat and SOCS box protein 14 1 HGANVNY(1)FCR 75.109 0.036186 337700000.0 0.0 0.0 0.0 4795.1 4169.7 2531.2 2889.3 6205.8 0.0 3995.0 True False 0.0 0.0 0.0 3689.663778556497 3590.809129261102 2372.923663860368 3146.4421026842383 5246.836205097244 0.0 3855.1362659833603 0.0 0.0 0.0 0.9570773959699049 0.9314350729818277 0.6155226430770762 0.8161688421879039 1.3609988968208084 0.0 1.0 11.912566140077104 -5.7557616966244085 24.999999981067944 0.8236556075239616 1.0742725101847663e-05 0.5634264120352963 0.32726702507951994 94.89719199557372 417846.07101728907 0.08507884594319075 0.14230092345946518 1.7548431443605702e-06 5.7557616966244085 -0.8236448647988598 HGAPAAPS(ph)PPPR ddPTM_PC-9_AZD4547_30min_R2 2 HGAPAAPSPPPR 12 0 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 HGAPAAPS(1)PPPR;HGAPAAPS(1)PPPR 82.705 0.011822 14093600.0 21483.3 22461.4 28626.0 38753.0 36119.0 31807.0 25263.1 32864.0 24081.6 28223.0 True False 28314.542519600436 29721.608293383066 28246.400536103887 29819.094577881577 31104.50030932241 29818.103261854725 27511.466958890443 27785.62393959131 25354.504212439217 27234.921360412634 1.0396410602733404 1.0913050895232237 1.0371390525533697 1.094884548527655 1.1420815172440486 1.0948481498168332 1.0101540810350855 1.0202204578412755 0.9309556608191019 1.0 14.733170081018002 -7.529586813374367 2.1146417311643946 0.9773697613432182 1.0843939547556238 0.6284321648106241 0.035270284607835004 0.22000708242844302 1.9492339532139895 0.02147431393461225 0.011090495505201681 2.9540183354250745e-08 7.529586813374367 0.10702419341240565 HGAPAAPS(ph)PPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HGAPAAPSPPPR 12 0 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 HGAPAAPS(1)PPPR 84.169 0.010355 7182500.0 8578.0 8548.4 11385.0 9036.7 14408.0 11132.0 11965.0 11070.0 7859.0 8292.8 True False 10030.08597677727 9397.028657592542 11656.461577852935 8530.40299637669 11584.855828693417 10548.218323233992 10831.58858090158 10779.424229634526 7973.923007232726 9796.218994231322 1.02387318849075 0.9592505703604779 1.189893936090756 0.8707852490231149 1.1825844068528242 1.0767642423516153 1.105690735096873 1.1003657876556436 0.8139796601044049 1.0 13.258009310336135 -8.248324552398516 24.942478091593955 0.9069898212227742 1.0637531192796297 0.2812534919495281 0.1001750999374576 805.7377628754996 1532402.4210339633 0.06484876682596787 0.024182217941495863 5.645149497471225e-09 8.248324552398516 0.15676329805685552 HGAPAAPS(ph)PPPR ddPTM_PC-9_Lapatinib_30min_R1 3 HGAPAAPSPPPR 12 0 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 HGAPAAPS(1)PPPR;HGAPAAPS(1)PPPR;HGAPAAPS(1)PPPR 123.26 0.0017984000000000001 8230300.0 40871.2 41013.6 45027.0 36256.3 37924.6 35148.3 30535.0 36505.1 39703.7 26697.6 True False 40288.36919313988 40918.635529068095 41325.05386924636 38922.709249471234 35693.94959063237 33645.089143689154 32115.95289109754 38201.26021441954 35231.85120750386 31312.244587684123 1.2866650003425908 1.3067934307450575 1.3197729646472078 1.24305075416984 1.1399358321527573 1.0745026294576978 1.025667540414191 1.2200102776868649 1.1251780787814047 1.0 14.934439309918474 -6.206052758799513 2.326531860728594 1.0992374360214667 1.3040015784975365 0.7404577729012837 0.056772379854898435 0.16523920746836743 1.7562375171122193 0.01919669973593348 0.025500230141068538 6.222246917108046e-07 6.206052758799513 0.20476414247606978 HGAPS(ph)PSHPISAPQAAAAAALR ddPTM_PC-9_AZD4547_30min_R2 2 HGAPSPSHPISAPQAAAAAALR 22 0 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;H0YF36 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 HGAPS(0.479)PS(0.479)HPIS(0.042)APQAAAAAALR;HGAPS(0.948)PS(0.051)HPIS(0.001)APQAAAAAALR 62.556000000000004 0.0043298 12621700.0 10416.1 13597.099999999999 15652.0 22631.0 22629.2 18185.0 11740.2 25536.9 17834.5 18267.8 True False 13728.20313166088 17992.096669217357 15444.444253164878 17413.772595464543 19487.5261884249 17047.889075261057 12785.055056218978 21590.75888458341 18777.195260146622 17628.24988228558 0.7787615460032813 1.0206399835129067 0.8761189769997995 0.9878333193451856 1.1054714063253486 0.967077797801827 0.7252594637353381 1.224781758186881 1.0651763723303924 1.0 14.105601631775457 -4.195626405251698 1.7304891985828381 0.9971722228051457 1.2515657548462294e-36 0.20212157788844243 0.12668219788035884 11.541441431069604 8.068451545581613 0.035368098557150056 31.5968240196505 6.37343549556463e-05 4.195626405251698 -0.9971722228051457 HGAPS(ph)PSHPISAPQAAAAAALR ddPTM_PC-9_Lapatinib_30min_R1 1 HGAPSPSHPISAPQAAAAAALR 22 0 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;H0YF36 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 HGAPS(0.809)PS(0.191)HPIS(0.001)APQAAAAAALR 55.051 0.007678399999999999 5555400.0 2696.0 6555.1 8888.1 3335.2 5489.7 9049.2 7455.2 6860.5 8404.6 3313.8 True False 2657.5545456141517 6539.922068694145 8157.3547270581785 3580.481733901048 5166.806639165462 8662.186810715502 7841.19377742624 7179.26387548658 7457.985443638426 3886.585914639054 0.6837760965489832 1.6826907245408225 2.0988484253835797 0.9212408557379249 1.3293946802267722 2.2287393102745696 2.0175017224994107 1.8471903190009158 1.9189040477781505 1.0 11.92428769264285 -6.735377609359527 24.832051530848947 1.8688562313376553 1.3805904667022826 0.18359669519149968 0.47072597323078913 342.11643613611204 325972.8370721675 0.15430812026473129 0.15425855433624813 1.8391721868979395e-07 6.735377609359527 -0.48826576463537275 HGECAQTIR ddPTM_PC-9_AZD4547_30min_R2 1 HGECAQTIR 9 0 E5RIM3;Q9Y263 E5RIM3 PLAA Phospholipase A-2-activating protein 0 91.63600000000001 0.0059943 0.0 2205.5 1259.3 2191.3 4616.3 4027.6 3587.7 2177.6 3160.8 3020.5 2805.8 False True 2906.8031227501724 1666.3440980463063 2162.2419302300164 3552.083356124034 3468.437261436557 3363.360551845703 2371.402181429826 2672.37098795826 3180.157463527035 2707.569796019053 1.0735838193438458 0.6154390185975396 0.7985913912207052 1.3119083250768537 1.2810149036734748 1.2422064084149782 0.8758415701477041 0.9869998520028751 1.174543115454615 1.0 11.402782812919584 -5.739472796811036 24.99067461633002 1.1251502111424747 0.807827938545201 0.39389095331699464 0.16731472173597373 240.56757997036124 273683.8784602588 0.04778071926840084 0.08267226819454804 1.8219111897667324e-06 5.739472796811036 -0.31732227259727375 HGEIDYEAIVK ddPTM_PC-9_Lapatinib_30min_R1 1 HGEIDYEAIVK 11 0 P62333;A0A087X2I1 P62333 PSMC6 26S protease regulatory subunit 10B 0 99.75200000000001 0.0037196 2850800.0 61457.0 49504.0 55368.0 51148.0 45301.0 50212.0 50025.0 46965.0 61669.0 45048.0 False True 60580.6119101665 49389.37652951669 50815.85676666071 54909.59454472615 42636.484245192776 48064.549809888944 52615.049725795136 49147.16535416184 54723.18781664066 52834.486777313075 1.1466111550491975 0.9347942895268985 0.961793326030392 1.0392756302556556 0.806982083972863 0.9097192523601398 0.9958467079950483 0.93020995096077 1.0357475042255655 1.0 15.689192310290023 -4.758208920343127 24.924741929365688 0.9527166541921249 1.1466114336130688 0.43062565325720004 0.0651766765049303 84.12974574951772 648994.1004060067 0.016269838121730825 0.1134954461870852 1.7449825151569948e-05 4.758208920343127 0.1938947794209439 HGENEHNLQGR ddPTM_PC-9_Lapatinib_30min_R1 1 HGENEHNLQGR 11 0 Q5W015;Q5VX20;A0A1W2PR17;Q16875-3;Q16875-2;Q16875;Q16875-4;F2Z2I2 Q5W015 PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3;6-phosphofructo-2-kinase;Fructose-2,6-bisphosphatase 0 103.31 0.0012439 630330.0 2137.8 1196.2 1112.6 1011.2 3046.9 1176.6 2498.6 2139.6 768.72 1788.6 False True 2107.3145799754943 1193.4302723943092 1021.1263227601993 1085.5670212643133 2867.687332435879 1126.2795607885623 2627.9652822563066 2239.0136269938184 682.1386586195339 2097.757126840309 1.0045560341628208 0.5689077430006789 0.48677051775685953 0.5174893734716658 1.3670254271786253 0.5368970251027063 1.2527500198340928 1.0673369182476684 0.3251752311512759 1.0 11.034631940562956 HGEPEEDIVGLQAFQER ddPTM_PC-9_Lapatinib_30min_R1 1 HGEPEEDIVGLQAFQER 17 0 E9PF10;O75694-2;O75694 E9PF10 NUP155 Nuclear pore complex protein Nup155 0 79.013 0.0185 0.0 10368.0 11784.0 14320.0 10190.0 13540.0 16880.0 9857.5 11308.0 14565.0 9431.2 False True 10220.150418741658 11756.714872006796 13142.664876798532 10939.406592843503 12743.603820664213 16158.081749201883 10367.873116882074 11833.410961883577 12924.53632375053 11061.37035371593 0.9239497541376801 1.0628624208443824 1.1881588317295078 0.9889739013366047 1.1520818319208666 1.4607667253247492 0.9373045821035288 1.0697961087532242 1.168438982734964 1.0 13.433242506536471 -4.835196862657544 3.150950473970982 1.1254744967428107 0.9057259627309263 0.1543803771132759 0.13860162923838643 0.5847717101444873 9.291171537410108 0.03574971548704709 0.29949652477350297 1.4615145299460265e-05 4.835196862657544 -0.21974853401188443 HGES(ph)AWNLENR ddPTM_PC-9_AZD4547_30min_R2 3 HGESAWNLENR 11 0 P18669 P18669 PGAM1 Phosphoglycerate mutase 1 1 HGES(1)AWNLENR;HGES(1)AWNLENR;HGES(1)AWNLENR 109.95 0.0019966 25208100.0 28837.5 23237.300000000003 38790.0 60884.0 37942.0 35514.0 30668.6 38193.0 36989.0 37102.0 True False 38007.225142737756 30748.30279483159 38275.619255064244 46848.134448423145 32674.408226592946 33293.30396584113 33398.0459870494 32291.149437828975 38944.16302545987 35803.07027296989 1.061563292001578 0.8588174857742723 1.069059691340523 1.3084948886015484 0.9126146997304033 0.9299008077242038 0.9328263116100353 0.9019100650205327 1.0877324969211202 1.0 15.12779568987862 HGES(ph)AWNLENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HGESAWNLENR 11 0 P18669 P18669 PGAM1 Phosphoglycerate mutase 1 1 HGES(1)AWNLENR;HGES(1)AWNLENR;HGES(1)AWNLENR;HGES(1)AWNLENR 115.06 0.0013962 28914900.0 39777.0 37111.8 41530.4 58423.0 47604.4 41874.5 47278.6 52061.4 47141.5 31621.7 True False 46510.46046843896 40796.014240658245 42520.6422409191 55149.74871992158 38276.65955104473 39678.527504155776 42800.02874057782 50694.84341361296 47830.85525454402 37354.46389276053 1.245111176055532 1.0921322377367784 1.1383014989316926 1.4763897797663177 1.0246876962531626 1.0622164895223047 1.145780832605462 1.3571294600600026 1.2804588868377218 1.0 15.188993036249055 -11.32080558890936 2.890843353196547 0.9481812467504631 1.1989194756279842 0.17144752482920822 0.13332243096858554 38117409.83204682 44994230.26649226 14195274.211647805 0.03453111677365089 4.7774308657271465e-12 11.32080558890936 0.25073822887752106 HGES(ph)AWNLENR ddPTM_PC-9_Lapatinib_30min_R1 4 HGESAWNLENR 11 0 P18669 P18669 PGAM1 Phosphoglycerate mutase 1 1 HGES(1)AWNLENR;HGES(1)AWNLENR;HGES(1)AWNLENR;HGES(1)AWNLENR 131.08 0.00017663 26415700.0 47976.4 43734.0 38465.0 44697.7 37182.8 39569.4 31906.1 40264.8 41987.3 31547.9 True False 47292.24773820579 43632.736610008964 35302.55617919382 47984.91796515613 34995.78080819748 37877.1090027766 33558.04174025373 42135.64960187918 37258.248128129795 37000.912480065606 1.2781373368476976 1.1792340697953403 0.9540996103329403 1.2968576921179498 0.9458085885598524 1.023680403103114 0.9069517341858329 1.138773256594143 1.0069548459974555 1.0 15.175273229054095 -1.5228787460263027 0.5132288235283693 1.0161450060130282 10.233683829987648 0.365615816039904 0.10620898787096737 126.4151499468195 1.2941570396999047 0.05567405331927089 1264.3954559657243 0.029999999948470555 1.5228787460263027 9.21753882397462 HGESAWNLENR ddPTM_PC-9_AZD4547_30min_R2 3 HGESAWNLENR 11 0 P18669 P18669 PGAM1 Phosphoglycerate mutase 1 0 ;; 150.09 0.00027437 53800600.0 128881.0 110086.0 226729.0 335018.0 256008.0 259647.0 221158.0 318325.0 219427.0 243459.0 False True 169862.4771086667 145669.14665093747 223722.42531790322 257784.77607650307 220465.70821974622 243411.2320442291 240840.63356018448 269135.185630794 231025.46325090126 234935.57451315233 0.7230172674388116 0.6200386933856308 0.9522713866621279 1.0972573081394772 0.938409215703533 1.0360765182056424 1.0251348015696173 1.1455701682834205 0.98335666588445 1.0 17.841905660702082 -5.369192924618339 4.151178530199536 1.0336339111014927 0.6721228539479616 0.8475165868873222 0.06012677025932127 0.0728603275090125 2.1271561917009607 0.015614911091446745 0.03501563298904326 4.2737299405929095e-06 5.369192924618339 -0.36151105715353116 HGESAWNLENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HGESAWNLENR 11 0 P18669 P18669 PGAM1 Phosphoglycerate mutase 1 0 ;;; 167.84 6.5048e-05 49233900.0 142102.0 171758.0 184400.0 229857.0 277672.0 220091.0 261758.0 213151.0 218986.0 157816.0 False True 166157.06195756642 188808.99913092278 188796.79534089472 216978.8574964484 223264.16488512972 208549.04051193772 236962.38727619188 207556.012102153 222188.25596918984 186426.79152923098 0.8912724431644453 1.0127782470649787 1.0127127854973148 1.1638823782601386 1.1975969926517926 1.1186645374371422 1.2710747491410703 1.1133378974105717 1.1918257786159003 1.0 17.508249680077462 -5.4130915842232685 1.4251473193286637 1.163070966207712 0.9144710131665766 0.5683431167293951 0.07213695774211078 0.34112823142467263 1.2103448063304008 0.02105921596099146 0.08604031126839001 3.862855083957937e-06 5.4130915842232685 -0.24859995304113547 HGESAWNLENR ddPTM_PC-9_Lapatinib_30min_R1 4 HGESAWNLENR 11 0 P18669 P18669 PGAM1 Phosphoglycerate mutase 1 0 ;;; 143.0 0.00011630000000000001 58800700.0 328416.0 274517.0 435662.0 317655.0 366641.0 437569.0 306286.0 318652.0 449675.0 276950.0 False True 323732.72761588206 273881.3727527748 399843.55206395313 341016.4083660161 345075.8972239398 418855.1938931585 322143.9904110925 333457.73521631863 399027.86621232546 324820.438487322 0.9966513471981462 0.843177769318431 1.2309679585620021 1.0498613016906146 1.0623589415461256 1.2894976555162392 0.9917602226981356 1.026590989068361 1.228456768516738 1.0 18.30928288767604 -5.253013543441225 24.979011164425852 1.1092339517749539 0.9199145565848212 0.34110635993296934 0.10563603260526332 668.4133488854125 1981548.4854344537 0.026036109967898246 0.06649288648828962 5.584527791567596e-06 5.253013543441225 -0.18931939519013263 HGGICDCQTSR ddPTM_PC-9_AZD4547_30min_R2 2 HGGICDCQTSR 11 0 Q10713 Q10713 PMPCA Mitochondrial-processing peptidase subunit alpha 0 ; 135.8 6.3027e-05 1666170.0 4296.4 3066.3999999999996 5463.5 9307.0 6836.6 6613.8 5659.0 10241.5 6616.1 7193.6 False True 5662.5658293284205 4057.553833279753 5391.050420212514 7161.4149417166045 5887.456098305976 6200.238040470806 6162.640037064376 8658.911501257435 6965.813538964151 6941.7542535614275 0.8157254812676887 0.5845141854738012 0.7766121103245143 1.0316433973505301 0.8481222300955772 0.8931802846938595 0.887764074031095 1.2473664703435776 1.003465879736434 1.0 12.761084577595328 -6.042569637617808 0.5071435809051369 1.0696782885734202 0.6383561078906869 0.4805051345101039 0.1211783456454439 1.265081761342324 0.5787131701469793 0.09893198948769986 0.2844460548126825 9.066305778512573e-07 6.042569637617808 -0.4313221806827333 HGGICDCQTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HGGICDCQTSR 11 0 Q10713 Q10713 PMPCA Mitochondrial-processing peptidase subunit alpha 0 ; 120.86 0.00069263 492790.0 1506.52 2858.66 3637.3 3470.2999999999997 6003.9 4847.799999999999 2776.42 3882.5 2980.5 1917.9299999999998 False True 1761.5440808736882 3142.448872574225 3724.0270265370664 3275.8703418644004 4827.478894356769 4593.572833935839 2513.4173980599057 3780.588488848786 3024.084173947975 2265.635526674473 0.7775054990682034 1.3870054717877542 1.6437008436229978 1.4458946742739165 2.130739405133976 2.027498589183204 1.109365283368914 1.6686657868567143 1.3347619854755552 1.0 11.1457000777924 -8.569966788961603 4.277373961344978 1.0001698105312167 1.5429725983466536 0.1531866638501599 0.3760813028278319 0.4712891768440465 27.49674220309945 0.37792678252064593 0.09876002178114315 2.691740636806135e-09 8.569966788961603 0.5428027878154369 HGGICDCQTSR ddPTM_PC-9_Lapatinib_30min_R1 2 HGGICDCQTSR 11 0 Q10713 Q10713 PMPCA Mitochondrial-processing peptidase subunit alpha 0 ; 114.86 0.00090256 344980.0 4430.6 6517.1 4054.7 4373.9 5033.299999999999 4144.1 4233.1 1630.38 5927.4 4283.299999999999 False True 4367.41883152747 6502.010055359429 3721.3382175946267 4695.571196902669 4737.251189848536 3966.8665033689276 4452.269205282626 1706.1334067948126 5259.793793710876 5023.662697861506 0.8693694410229037 1.2942767949224045 0.7407619582379091 0.9346907782844377 0.9429875122517898 0.7896363155626591 0.8862595825109609 0.3396194190189335 1.0470037719590306 1.0 12.294523885742992 -5.886801201992874 0.7988614933479687 0.778155875045783 1.059902322946546 0.08399776224551903 0.2224858646769105 1.572473618251933 1.9029991039253007 0.10480343815795964 0.30026056785930816 1.2977731898457968e-06 5.886801201992874 0.2817464479007631 HGGPGPGGPEPELS(ph)PITEGSEAR ddPTM_PC-9_AZD4547_30min_R2 3 HGGPGPGGPEPELSPITEGSEAR 23 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 HGGPGPGGPEPELS(0.831)PIT(0.148)EGS(0.02)EAR;HGGPGPGGPEPELS(0.803)PIT(0.19)EGS(0.007)EAR;HGGPGPGGPEPELS(0.974)PIT(0.023)EGS(0.002)EAR 204.23 2.7006999999999998e-30 42533300.0 52568.5 43526.4 70743.6 93061.8 73104.0 80320.3 57645.5 85389.3 61522.8 67908.1 True False 69284.18950727388 57595.457594856474 69805.49364095286 71607.83980047735 62954.77146689301 75297.85894372781 62775.837825869305 72194.34573590982 64774.76960671444 65530.65808861701 1.0572790130320526 0.8789085792022754 1.0652341312756999 1.0927379930114873 0.9606918853425731 1.1490478066297247 0.9579613520892409 1.1016880928966335 0.9884651168788755 1.0 15.999882399548783 -5.311523243539392 24.999971792929443 1.0432002347834126 0.968093121477507 0.13304169165970492 0.07239304637336641 550.938595381391 275006.74562130275 0.01728632150903114 0.03598443093785982 4.880639792534416e-06 5.311523243539392 -0.07510711330590558 HGGPGPGGPEPELS(ph)PITEGSEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HGGPGPGGPEPELSPITEGSEAR 23 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 HGGPGPGGPEPELS(0.986)PIT(0.011)EGS(0.003)EAR;HGGPGPGGPEPELS(0.978)PIT(0.017)EGS(0.005)EAR 146.67 2.6275e-07 29105000.0 36434.6 30393.9 37005.3 40578.0 46316.4 44097.0 44246.6 45263.0 41516.0 39496.0 True False 42602.258163848135 33411.205525712656 37887.64669538176 38304.546215651004 37241.03390505937 41784.475691668136 40055.24173035684 44074.89421011273 42123.09295944446 46656.31214983602 0.9131081348013886 0.7161132971335816 0.812058325006618 0.820993868796071 0.7981992615588727 0.8955803355712716 0.858517098430756 0.9446716248932598 0.9028380302362262 1.0 15.509784656579894 -7.733211232751119 0.5645683949316385 0.9913408066724742 0.798737738604692 0.5654595955906923 0.05133709239373979 0.5437105494086957 0.3740717884777301 0.04750336012594304 0.028901653413434328 1.848369387850385e-08 7.733211232751119 -0.19260306806778216 HGGPGPGGPEPELS(ph)PITEGSEAR ddPTM_PC-9_Lapatinib_30min_R1 2 HGGPGPGGPEPELSPITEGSEAR 23 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 HGGPGPGGPEPELS(0.991)PIT(0.008)EGS(0.001)EAR;HGGPGPGGPEPELS(0.915)PIT(0.071)EGS(0.015)EAR 204.0 2.7736e-30 31761000.0 31725.0 25685.0 37423.0 28290.0 38871.0 36405.0 39039.0 28863.0 44908.0 30442.0 True False 31272.595682347543 25625.52796058169 34346.22539695753 30370.540972673494 36584.68420332638 34848.04301419994 41060.248400705954 30204.080349561886 39849.98813779533 35703.859138584754 0.8758883895705157 0.7177243182905255 0.9619751541042788 0.8506234817583738 1.0246703041629954 0.9760301506606622 1.1500226975837637 0.8459612231922762 1.1161255141388875 1.0 15.123792399439562 -5.9164201385242645 1.1356396713122405 1.0198111891424337 0.8059252936786762 0.41933041003747806 0.09536222138260567 0.48561798785370647 1.2603500235762195 0.0343072327464202 0.07616442658388717 1.2122155799897037e-06 5.9164201385242645 -0.21388589546375758 HGGS(ph)PQPLAT(ph)TPLSQEPVNPPS(ph)EASPTR ddPTM_PC-9_AZD4547_30min_R2 2 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 3 HGGS(0.999)PQPLAT(0.691)T(0.287)PLS(0.023)QEPVNPPS(0.599)EAS(0.303)PT(0.098)R;HGGS(0.994)PQPLAT(0.839)T(0.144)PLS(0.028)QEPVNPPS(0.738)EAS(0.189)PT(0.067)R 81.907 1.2978e-05 6482500.0 5788.2 6403.5 7519.1 5808.06 8187.6 6493.2 5897.1 8843.400000000001 6222.0 6631.4 True False 7628.727197960803 8473.306147732483 7419.391821107333 4469.101500632487 7050.893068263472 6087.179177535607 6421.930475803558 7476.85573111556 6550.882217535245 6399.236704441065 1.1921308040795666 1.3241120057103084 1.1594182499857024 0.6983804017643127 1.1018334520068866 0.951235195489973 1.0035463247275638 1.1683980569005408 1.0236974376942392 1.0 12.643684116588746 -5.5322591481849654 24.994632339011968 0.997080153855852 1.2540324043125326 0.4597189697952746 0.11880578891394014 164.58982269528832 438557.9115542211 0.03220197971246056 0.05586839056899542 2.935897247732803e-06 5.5322591481849654 0.2569522504566806 HGGS(ph)PQPLAT(ph)TPLSQEPVNPPS(ph)EASPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 3 HGGS(1)PQPLAT(0.702)T(0.294)PLS(0.003)QEPVNPPS(0.533)EAS(0.352)PT(0.114)R 76.04899999999999 4.7763e-05 3442300.0 3657.0 5795.1 4449.1 4447.1 4489.7 3742.6 4586.6 2909.5 3830.9 3317.8 True False 4276.057870957624 6370.399229518335 4555.183417305712 4197.943404692732 3609.97551458112 3546.331467529244 4152.124043891614 2833.1287078700684 3886.9196651492375 3919.290876309651 1.0910284553781064 1.6253958765919954 1.1622468352220923 1.0710976901631388 0.9210787431986222 0.9048400793534415 1.0594069628741603 0.722867681241792 0.9917405438427438 1.0 11.936376933447253 -5.743062577402597 2.1537247015557783 0.9282967408107704 1.361105219642657 0.540971004268806 0.15092839944769437 0.20628122917591946 1.9504106099617076 0.04275959902555434 0.08348249171720028 1.8069137494219599e-06 5.743062577402597 0.43280847883188656 HGGS(ph)PQPLAT(ph)TPLSQEPVNPPSEAS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 1 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 3 HGGS(1)PQPLAT(0.711)T(0.288)PLS(0.002)QEPVNPPS(0.327)EAS(0.517)PT(0.156)R 89.117 4.5784e-07 3566100.0 4447.8 5613.2 9383.2 8220.2 10064.0 8926.2 8833.8 10827.0 8200.5 8240.7 True False 5862.107880012794 7427.557127891305 9258.772637126036 6325.1598908239885 8666.787317285103 8368.04330291973 9619.991086661825 9153.935929708963 8633.961688347441 7952.195601273862 0.7371684719467594 0.9340259596609375 1.164303935839163 0.7953979263048763 1.089860932985196 1.05229344479143 1.2097276738415235 1.151120569549697 1.0857330630756072 1.0 12.957137528171591 -6.409510420187173 7.638113630252452 1.1112032616025591 0.9281692082967066 0.3808716803954345 0.11735629083076039 0.31540738253006567 19.18195854334124 0.03691695450441074 0.041831923135751035 3.8948396255963635e-07 6.409510420187173 -0.18303405330585254 HGGS(ph)PQPLAT(ph)TPLSQEPVNPPSEAS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 3 HGGS(0.991)PQPLAT(0.716)T(0.292)PLS(0.001)QEPVNPPS(0.167)EAS(0.641)PT(0.192)R 94.428 3.8563e-05 0.0 3736.9 5561.8 4398.5 3387.7 4508.6 873.87 4565.6 1487.0 1142.2 3018.9 True False 4369.483362860688 6113.938747344327 4503.376921404144 3197.898152071587 3625.1721952559064 828.042718839786 4133.113315918447 1447.9678256067348 1158.9025141698974 3566.202672400751 1.225248188129244 1.7144114647944144 1.2627933225041559 0.8967236149589829 1.0165356622357802 0.23219171620505558 1.158967589785371 0.40602510811085496 0.32496821426857647 1.0 11.800172980378425 -5.9243088136806135 1.3200596685849761 0.6332566492005925 1.493444708740152 0.5208102815835707 0.31006498246820186 0.3362392994977794 1.1881769159320548 0.10773444013176645 0.21717401988619797 1.1903952529244456e-06 5.9243088136806135 0.8601880595395593 HGGS(ph)PQPLAT(ph)TPLSQEPVNPPSEAS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 2 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 3 HGGS(0.998)PQPLAT(0.717)T(0.285)PLSQEPVNPPS(0.4)EAS(0.463)PT(0.136)R;HGGS(0.998)PQPLAT(0.498)T(0.498)PLS(0.007)QEPVNPPS(0.17)EAS(0.627)PT(0.203)R 96.45100000000001 2.5418e-09 9979900.0 20618.1 28221.3 22905.9 21302.9 28924.0 24775.1 27714.0 28837.0 22962.7 26590.3 True False 20324.082113103534 28155.95531376151 21022.665321330987 22869.586330391172 27222.74718677193 23715.526726578875 29148.895314356545 30176.872294644225 20376.398918049166 31186.397925652378 0.6516970046221964 0.9028280656485123 0.6740972577675856 0.7333192626128774 0.8729045031641777 0.7604445625017715 0.9346669462708329 0.9676292968038553 0.6533745566456893 1.0 14.92862930850712 -6.634275027381067 1.3780689596557092 0.8777249664596143 0.7498334115979046 0.21148021269436645 0.11413294056666358 0.7178179065980334 2.8412492084473535 0.049030626687756165 0.04954268292288893 2.321266333308467e-07 6.634275027381067 -0.12789155486170967 HGGS(ph)PQPLATT(ph)PLSQEPVNPPS(ph)EASPTR ddPTM_PC-9_AZD4547_30min_R2 1 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 3 HGGS(0.995)PQPLAT(0.449)T(0.548)PLS(0.008)QEPVNPPS(0.629)EAS(0.312)PT(0.059)R 82.713 5.5936e-05 0.0 1015.9 2755.0 3314.4 3534.7 2191.3 2160.0 2471.7 2614.8 2643.2 2136.0 True False 1338.9350679673096 3645.499873038649 3270.4488904095106 2719.8295255706116 1887.0758195913027 2024.9348585407697 2691.676511682634 2210.74274212644 2782.9141558002502 2061.219290147801 0.6495839983485213 1.7686133108026785 1.586657424584359 1.3195245836145773 0.9155143407647756 0.9823966174872982 1.3058661562834615 1.072541263655609 1.3501300754859031 1.0 11.00928228394932 -6.020421130144393 22.68115097475377 1.1125084672848173 1.3907799387540012 0.11284849999123803 0.299055179701404 429.11967714069004 476612.33711358666 0.086475539673535 0.11333596080736054 9.540669900198557e-07 6.020421130144393 0.27827147146918385 HGGS(ph)PQPLATT(ph)PLSQEPVNPPSEAS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 3 HGGS(0.984)PQPLAT(0.176)T(0.477)PLS(0.363)QEPVNPPS(0.338)EAS(0.49)PT(0.172)R 69.598 0.0016504000000000002 0.0 2723.9 3326.7 2764.3 2494.1 3134.8 3035.6 1914.5 1897.0 2764.4 1226.7 True False 3185.0024705226874 3656.952790605624 2830.211395666128 2354.363662981299 2520.558443350092 2876.407792131613 1733.1447002203158 1847.2057600376436 2804.824120269012 1449.0909994481424 2.1979313043388116 2.5236184559826143 1.9530943168813815 1.6247176084027242 1.739406596487037 1.9849738858546744 1.1960219895647337 1.2747341338405354 1.9355748682016338 1.0 10.500932480198957 -1.5228787452803583 0.16283234908183794 1.0128973542257727 6.566352274033353 0.6072320583441602 0.283105607657503 42.01830231990131 0.44083755238647543 0.8246161749892771 56.19681533824529 0.02999999999999857 1.5228787452803583 5.55345491980758 HGGS(ph)PQPLATT(ph)PLSQEPVNPPSEAS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 1 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 3 HGGS(0.999)PQPLAT(0.111)T(0.888)PLS(0.003)QEPVNPPS(0.202)EAS(0.609)PT(0.189)R 90.883 2.8833000000000004e-07 2463000.0 3639.4 3419.2 4562.7 5218.2 6044.5 6837.9 3926.7 4126.9 5349.5 3615.2 True False 3587.50148861578 3411.2830524750234 4187.57241853133 5601.963835404909 5688.97439394423 6545.458956923432 4130.005312509338 4318.650839989153 4746.982977267661 4240.082503048797 0.8460923781639194 0.8045322349322609 0.9876157870796831 1.321192177599578 1.3417131364433639 1.543710282103467 0.9740389036155999 1.0185299075864354 1.1195496724071718 1.0 12.049876621521634 -5.545711382280658 4.387808126207395 1.200755142650929 0.8359448220418582 0.430162305818257 0.1690199390371951 0.1936494139050737 8.87784969500096 0.050909970396547516 0.09701273807529757 2.846352070295194e-06 5.545711382280658 -0.3648103206090709 HGGS(ph)PQPLATTPLS(ph)QEPVNPPS(ph)EASPTR ddPTM_PC-9_AZD4547_30min_R2 2 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 3 HGGS(0.99)PQPLAT(0.09)T(0.101)PLS(0.819)QEPVNPPS(0.506)EAS(0.373)PT(0.121)R;HGGS(0.947)PQPLAT(0.145)T(0.138)PLS(0.77)QEPVNPPS(0.526)EAS(0.372)PT(0.102)R 58.059 0.0026697 1652400.0 1688.96 1704.6999999999998 1988.4299999999998 2766.21 1911.19 2091.4 1855.73 2786.6800000000003 2620.57 2954.4900000000002 True False 2226.014147449617 2255.710937774586 1962.0621189829174 2128.503022018471 1645.8542580407525 1960.6244273852599 2020.8863749746388 2356.0626375359166 2759.087980200313 2851.0542043767673 0.7807687921304246 0.7911848656934526 0.688188290482474 0.7465670132651006 0.5772791886994417 0.6876840238166735 0.7088207484348404 0.8263829687695978 0.9677430811258259 1.0 11.477279752784735 -8.09819005270789 2.124383785286119 0.9978601369678416 0.7081987707329213 0.7868630460082601 0.05655978503178269 0.15640432054497908 1.2619647586753315 0.05405926916390043 0.017016769600628538 7.97645551191035e-09 8.09819005270789 -0.28966136623492034 HGGS(ph)PQPLATTPLS(ph)QEPVNPPSEAS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 1 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 3 HGGS(0.998)PQPLAT(0.005)T(0.008)PLS(0.988)QEPVNPPS(0.093)EAS(0.744)PT(0.163)R 96.931 1.5433e-09 2708300.0 991.33 2886.1 2562.5 3251.5 2358.3 2997.9 2427.7 3219.7 4600.3 2725.8 True False 1306.552319055057 3818.975384238418 2528.519575692244 2501.916910174229 2030.8907522211323 2810.4408390830417 2643.760596921927 2722.1693463456118 4843.462466301412 2630.370571668949 0.4967179655701744 1.4518773230554007 0.9612788414401695 0.9511651845263699 0.7720930176513298 1.068458136413775 1.0050905470876228 1.0348995596534587 1.8413612585500732 1.0 11.361050348152302 -8.035379142800549 23.532152635728036 1.4264978971871607 0.9773180098074669 0.2772641502298616 0.2936547919450009 366.8149566816373 243980.45893040963 0.182782800851679 0.06917661728222853 9.217663658648666e-09 8.035379142800549 -0.44917988737969383 HGGS(ph)PQPLATTPLS(ph)QEPVNPPSEAS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 3 HGGS(0.995)PQPLAT(0.318)T(0.318)PLS(0.369)QEPVNPPS(0.191)EAS(0.405)PT(0.404)R 63.72 0.0054989 0.0 2396.5 2874.2 2108.2 648.69 2430.2 927.09 2691.3 984.16 1102.2 1148.6 True False 2802.1801169674422 3159.5315810739444 2158.4674833930217 612.3460023813556 1954.0197553366684 878.47176835133 2436.360580675339 958.326842803714 1118.3175898424618 1356.8320876874022 2.0652372112923016 2.328609125436502 1.590814001953576 0.4513056611338283 1.4401338036360258 0.6474432439526144 1.7956242358830823 0.7062973020022659 0.824212221976953 1.0 10.406026478337465 -5.511929111154822 4.966596014234855 1.0051657648860155 2.1598434001194717 0.6279276821967039 0.3763212962312283 0.10979155106108499 7.719614312375875 0.09747091666001255 0.19184679792391274 3.0765989596163444e-06 5.511929111154822 1.1546776352334562 HGGS(ph)PQPLATTPLSQEPVNPPS(ph)EASPTR ddPTM_PC-9_AZD4547_30min_R2 1 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 HGGS(0.889)PQPLAT(0.089)T(0.017)PLS(0.004)QEPVNPPS(0.598)EAS(0.297)PT(0.105)R 70.834 0.00029505 89477000.0 22746.0 33811.0 32777.0 30896.0 35603.0 38941.0 38239.0 46403.0 35416.0 35532.0 True False 29978.754853808834 44739.74453985838 32342.355563888646 23773.404538441646 30660.138002514068 36506.013114090754 41642.19692124131 39232.48258486053 37288.01745680298 34288.035495099066 0.874321156663928 1.3048208768406466 0.9432548437635476 0.6933440249687002 0.8941934864392115 1.0646866344765862 1.2144818540914484 1.1442032772763606 1.0874935503998973 1.0 15.065417628160475 -6.939075253773736 5.469843577045876 1.1258646560075654 0.9494830488493955 0.2222308782244875 0.15042359841553843 0.3274776716011272 19.550501669638 0.0584238038615389 0.05106397295873212 1.1506009975798193e-07 6.939075253773736 -0.17638160715816986 HGGS(ph)PQPLATTPLSQEPVNPPS(ph)EASPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 HGGS(1)PQPLATTPLSQEPVNPPS(0.648)EAS(0.292)PT(0.059)R;HGGS(0.998)PQPLAT(0.001)T(0.001)PLSQEPVNPPS(0.817)EAS(0.143)PT(0.04)R 104.36 8.1136e-10 20346400.0 21341.0 34616.0 31771.0 25165.0 28314.0 24977.0 30006.0 18041.8 21781.3 19194.1 True False 24953.60979603681 38052.44771082583 32528.541132188482 23755.086636030792 22766.074953749674 23667.162150504464 27163.61445537258 17568.221866867225 22099.810306328814 22673.838389588 1.1005463374695172 1.678253459206969 1.4346287811209697 1.0476870403618697 1.0040679730787898 1.0438092458739852 1.1980157037657249 0.7748234579873643 0.9746832418315735 1.0 14.46874102104159 -5.784122974652872 5.3337370206706005 1.003480540611487 1.4345222767080978 0.5568410108462445 0.16250789490723572 0.11977609257656668 9.402191358612946 0.04509818789023645 0.07133074584542004 1.6439061694875065e-06 5.784122974652872 0.4310417360966108 HGGS(ph)PQPLATTPLSQEPVNPPS(ph)EASPTR ddPTM_PC-9_Lapatinib_30min_R1 1 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 HGGS(1)PQPLATTPLSQEPVNPPS(0.769)EAS(0.115)PT(0.115)R 95.81700000000001 3.3452e-09 14091000.0 10961.0 17625.0 12566.0 9210.8 14630.0 13658.0 14570.0 15456.0 14821.0 7369.7 True False 10804.694129998776 17584.190395376772 11532.871986162743 9888.192958328067 13769.49216368667 13073.879178353045 15324.363308442471 16174.142184902073 13151.702907951023 8643.542825492019 1.2500307279247773 2.034373028559134 1.3342760276664973 1.1439976821963855 1.5930379986175245 1.5125602362719637 1.7729261736572883 1.8712398968164294 1.5215639204289342 1.0 13.07740705181115 -6.469639208231507 24.979473916891966 1.5991478798799437 1.4621073736065295 0.007173844085263337 0.3109223289349481 1267.2227794182347 594567.7317265995 0.09637199004309618 0.10927475319830458 3.391257691511742e-07 6.469639208231507 -0.13704050627341413 HGGS(ph)PQPLATTPLSQEPVNPPSEAS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 3 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 HGGS(1)PQPLATTPLSQEPVNPPS(0.123)EAS(0.514)PT(0.362)R;HGGS(0.995)PQPLAT(0.004)T(0.002)PLSQEPVNPPS(0.261)EAS(0.37)PT(0.37)R;HGGS(0.997)PQPLAT(0.003)TPLSQEPVNPPS(0.123)EAS(0.438)PT(0.438)R 129.19 5.6628e-12 124598000.0 96762.0 107876.0 113374.0 101692.0 103228.0 134379.0 116702.0 142504.0 122271.0 103476.0 True False 127530.30322536935 142744.80736984286 111870.58668274432 78248.48052573821 88896.57404498277 125976.25988696773 127088.25191826951 120483.28121614878 128733.9954388063 99853.33673564292 1.2771761805316524 1.4295446906071163 1.1203490072536735 0.7836341086217021 0.8902714416077284 1.2616129215639937 1.272749174669343 1.2066024547093772 1.289230782338537 1.0 16.60752301764967 -5.293359519549196 10.814553862907887 1.1030805693891188 1.3533008266816748 0.27137559491350416 0.16405859809898599 1.0772089380491727 363.62100952487134 0.04858153103685857 0.10208513162138484 5.0890940902990895e-06 5.293359519549196 0.25022025729255604 HGGS(ph)PQPLATTPLSQEPVNPPSEAS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 HGGS(1)PQPLATTPLS(0.002)QEPVNPPS(0.258)EAS(0.369)PT(0.369)R;HGGS(1)PQPLATTPLSQEPVNPPS(0.366)EAS(0.5)PT(0.134)R;HGGS(0.985)PQPLAT(0.011)T(0.004)PLSQEPVNPPS(0.244)EAS(0.378)PT(0.378)R;HGGS(1)PQPLATTPLSQEPVNPPS(0.232)EAS(0.58)PT(0.189)R 118.65 5.6628e-12 169000600.0 71448.6 121727.5 94355.0 81885.4 89346.0 68975.5 86748.5 57772.1 68359.1 58844.7 True False 83543.43680582529 133811.80173097848 96604.78104333012 77297.62651404859 71839.29267562751 65358.303355571836 78531.05407524771 56255.643589599735 69358.72251478859 69512.77829561118 1.2018428676602035 1.9249957347687676 1.3897413311910374 1.1119916137624573 1.0334688734511885 0.9402343706883366 1.1297355105170055 0.8092849252890751 0.9977837775355857 1.0 16.084990587445553 -5.740286322340436 2.6791593961113653 0.9868101756730274 1.5807887791097517 0.6285792990983559 0.18097707689848616 0.1524502986809202 2.229600550775718 0.04979122776501619 0.09099678005351289 1.8185015587837079e-06 5.740286322340436 0.5939786034367243 HGGS(ph)PQPLATTPLSQEPVNPPSEAS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 1 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 HGGS(0.999)PQPLAT(0.001)TPLSQEPVNPPS(0.086)EAS(0.775)PT(0.139)R 131.59 2.943e-10 117400000.0 17306.0 29993.0 28806.0 20383.0 33623.0 31563.0 29519.0 32031.0 28789.0 23553.0 True False 17059.213266468283 29923.55305126441 26437.681874375605 21882.03381569471 31645.36124536139 30213.124066946646 31047.349382423727 33519.277194914466 25546.47965839026 27624.10466760024 0.6175480969153977 1.0832406483878243 0.9570511765901261 0.7921354946703381 1.1455705669432104 1.0937231968420325 1.1239223770694202 1.2134068270537852 0.924789417278498 1.0 14.75364008522834 -6.268785861737144 24.973505805370735 1.096764482370014 0.8850155755618976 0.38779850678914907 0.13428363452510386 602.3227171555473 2047522.295531598 0.040181339124539084 0.046466274154287564 5.385352534867713e-07 6.268785861737144 -0.21174890680811642 HGGS(ph)PQPLATTPLSQEPVNPPSEASPT(ph)R ddPTM_PC-9_Lapatinib_30min_R1 2 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 HGGS(0.999)PQPLAT(0.001)T(0.001)PLSQEPVNPPS(0.228)EAS(0.222)PT(0.55)R;HGGS(0.996)PQPLAT(0.002)T(0.002)PLSQEPVNPPS(0.143)EAS(0.27)PT(0.586)R 137.36 1.2194e-11 126497000.0 39369.0 50365.0 39089.0 37773.0 53353.0 55474.0 52699.0 52577.0 55298.0 46895.0 True False 38807.59084060962 50248.38293691635 35875.253307903506 40550.95242703414 50214.88143603381 53101.506336210005 55427.49636181265 55019.91936177507 49069.756926244874 55000.7382663403 0.7055830896793496 0.9135946992854762 0.6522685774539625 0.7372801475985055 0.9129855892637105 0.9654689738720726 1.0077591339484533 1.000348742508544 0.8921654231007822 1.0 15.747163363387468 -6.4028772294919305 3.395443674726644 0.9733566546616147 0.7567053084245874 0.6937762127079925 0.06945062056367447 0.14809268693242705 3.163047122895144 0.02275068239169325 0.025887175410563568 3.954784018758039e-07 6.4028772294919305 -0.2166513462370273 HGGS(ph)PQPLATTPLSQEPVNPPSEASPTR ddPTM_PC-9_AZD4547_30min_R2 2 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 HGGS(0.986)PQPLAT(0.007)T(0.004)PLS(0.002)QEPVNPPSEASPTR;HGGS(0.969)PQPLAT(0.015)T(0.015)PLS(0.001)QEPVNPPSEASPTR 82.581 2.8241e-06 32291000.0 25202.0 23162.0 39843.0 54084.0 43248.0 47659.0 30105.0 37616.0 34814.0 38407.0 True False 33215.71176583534 30648.663542403327 39314.65578704629 41615.76938947043 37243.76171481977 44678.87519592336 32784.28667888729 31803.311529688035 36654.19696581034 37062.38262018098 0.8962109129958883 0.8269480096974312 1.0607697888704792 1.1228573676968643 1.0048938865182409 1.2055046663836204 0.88457040160812 0.858102185593721 0.9889865241920962 1.0 15.177668010073495 -10.717431591063452 14.500732998322977 0.9999808208612129 0.985592284125136 0.0015224270062877965 0.11526277396938416 0.0 0.0 0.12015796704287472 0.029142587639838725 1.916762962471049e-11 10.717431591063452 -0.014388536736076873 HGGS(ph)PQPLATTPLSQEPVNPPSEASPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 HGGS(0.98)PQPLAT(0.006)T(0.014)PLSQEPVNPPSEASPTR;HGGS(0.998)PQPLAT(0.002)T(0.001)PLSQEPVNPPSEASPTR;HGGS(0.998)PQPLAT(0.001)T(0.001)PLSQEPVNPPSEASPTR 97.744 6.971399999999999e-10 18975000.0 39355.8 36263.7 41988.3 48810.8 53844.4 50373.6 44772.3 42538.3 51178.7 34370.4 True False 46017.95962751818 39863.720477555886 42989.460313514486 46076.08912274875 43293.97634525953 47731.91973834529 40531.14362061846 41421.714698054435 51927.09166691204 40601.48144406333 1.1334059248778185 0.9818292106527232 1.0588150674438093 1.1348376336027983 1.0663151886441793 1.1756201508091662 0.9982676045074421 1.0202020523591273 1.2789457384320326 1.0 15.309244748167075 -5.546187475345541 23.133019377741405 1.0952547554019085 1.048293702353806 0.035668093236683074 0.08853235567176808 311.3220961784094 308972.4094971385 0.02319126919684649 0.04017305846560714 2.843233481336786e-06 5.546187475345541 -0.04696105304810261 HGGS(ph)PQPLATTPLSQEPVNPPSEASPTR ddPTM_PC-9_Lapatinib_30min_R1 2 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 HGGS(0.999)PQPLAT(0.001)TPLSQEPVNPPSEASPTR;HGGS(1)PQPLATTPLSQEPVNPPSEASPTR 99.708 5.413799999999999e-10 23550000.0 35287.0 29435.0 38627.0 30625.0 38510.0 33876.0 27104.0 32428.0 33987.0 28213.0 True False 34783.80090915673 29366.845065981015 35451.237164531936 32877.26466200515 36244.91751357306 32427.202448812965 28507.312499109463 33934.72326423422 30159.02616102365 33089.579458540524 1.0512010572010737 0.8874952642651777 1.0713716446275916 0.9935836356940895 1.0953574541189322 0.9799823080085535 0.8615193352586303 1.025541086333618 0.9114357648096223 1.0 15.014089335843797 -6.998183569271486 24.999851187419814 0.9473236599047754 1.0162408751117347 0.1948428395086801 0.06719592079029502 98.98250275908072 1362285.39496037 0.0229995559368251 0.020143877825137515 1.0041912451207662e-07 6.998183569271486 0.06891721520695926 HGGSDNASTDCER ddPTM_PC-9_AZD4547_30min_R2 2 HGGSDNASTDCER 13 0 F5H7V1;O43847;O43847-2;G3V1R5 F5H7V1 NRD1 Nardilysin 0 ; 132.06 5.0981000000000005e-05 2668700.0 3979.8 3623.5 10028.1 15227.199999999999 10776.3 10762.5 8500.3 10025.900000000001 9836.9 12261.3 False True 5245.29361501752 4794.725513595479 9895.120841755856 11716.804297894822 9280.196757478094 10089.519173631956 9256.81023273694 8476.62752726231 10356.858451570628 11832.035619049258 0.44331286550327303 0.405232511798401 0.8362991086525279 0.9902610738452378 0.784327993615674 0.8527289384920462 0.7823514508216765 0.7164132867902433 0.8753234680004145 1.0 13.53041068018125 -5.263798790671945 23.696131662260264 0.8442571202671963 0.4242726261192942 0.8059482375916939 0.08436002450304282 37.8799777356923 380449.17178114766 0.022058481106310462 0.04978749685710326 5.447549802396634e-06 5.263798790671945 -0.4199844941479021 HGGSDNASTDCER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HGGSDNASTDCER 13 0 F5H7V1;O43847;O43847-2;G3V1R5 F5H7V1 NRD1 Nardilysin 0 ; 157.33 0.00017326 3019600.0 1612.87 4358.81 4778.8 4598.71 9488.7 8156.099999999999 3508.2200000000003 4589.23 9303.6 5039.4 False True 1885.897035365442 4791.523850428266 4892.744715699923 4341.059187918981 7629.45735020289 7728.379758006536 3175.896004286716 4468.76757519112 9439.647549318031 5953.0033281315455 0.3167975778635024 0.8048918480837084 0.8218951755962812 0.7292216967870397 1.2816148303074322 1.2982320573357085 0.5334947469756458 0.750674462766296 1.5856949894030767 1.0 12.539401985592455 -4.712274639773501 0.9052079069994362 1.0244134271815766 2.355597036871314e-16 0.3419992829711367 0.2951548354022722 3.254922727320592 1.9191977832818008 0.10717352556120906 3.4095036500356963 1.9396588853747635e-05 4.712274639773501 -1.0244134271815764 HGGSDNASTDCER ddPTM_PC-9_Lapatinib_30min_R1 1 HGGSDNASTDCER 13 0 F5H7V1;O43847;O43847-2;G3V1R5 F5H7V1 NRD1 Nardilysin 0 125.53 0.00011786 2204800.0 2645.6 4279.6 7724.9 5709.9 8263.4 7059.8 6351.0 7989.9 9310.8 4858.5 False True 2607.873258856378 4269.690849137839 7089.788540976324 6129.825093668022 7777.363058469479 6757.868811197603 6679.823704318342 8361.139922563985 8262.119656929377 5698.285251455682 0.4576593034176679 0.7492939824392093 1.2441968466154216 1.075731526796083 1.3648602544919417 1.1859477918328571 1.1722515475356234 1.4673080678837642 1.4499308638188548 1.0 12.476312128254335 -4.934405294832192 1.3037013560678195 1.2763204129070527 0.20565604979408356 0.7636864920701821 0.14618489267298956 0.4762842620728519 0.8709977895266121 0.043801201512933256 0.6345597371531715 1.1630401436872566e-05 4.934405294832192 -1.070664363112969 down HGGSPQPLATTPLSQEPVNPPS(ph)EASPTR ddPTM_PC-9_AZD4547_30min_R2 2 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 HGGSPQPLATTPLSQEPVNPPS(0.532)EAS(0.44)PT(0.028)R;HGGSPQPLATTPLSQEPVNPPS(0.718)EAS(0.261)PT(0.021)R 207.34 1.3014e-38 51904000.0 41080.0 39673.0 65411.0 75162.0 71903.0 98612.0 78600.0 96187.0 73853.0 75934.0 True False 54142.58548291861 52496.52140220048 64543.60740121186 57834.562141324095 61920.5095861239 92445.7760511215 85595.24773162388 81323.50930737196 77756.71880611226 73275.57377251094 0.7388899560310233 0.7164259343117468 0.8808338724387466 0.7892747768973529 0.8450361614139029 1.2616179074643044 1.1681279766892065 1.1098310817714836 1.061154690477257 1.0 16.16104473929832 -6.651213208244378 5.97762533640658 1.1289020994475123 0.7883345567928587 0.8226835028569319 0.07595251558656081 0.08593576515727917 4.207911092279852 0.026016310813477453 0.0259248782204756 2.2324759640547648e-07 6.651213208244378 -0.3405675426546536 HGGSPQPLATTPLSQEPVNPPS(ph)EASPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 HGGSPQPLATTPLSQEPVNPPS(0.428)EAS(0.286)PT(0.286)R;HGGSPQPLATTPLSQEPVNPPS(0.913)EAS(0.071)PT(0.015)R;HGGSPQPLATTPLSQEPVNPPS(0.653)EAS(0.26)PT(0.088)R 166.89 7.4332e-14 54686000.0 47068.0 89187.0 101634.0 83606.0 97472.0 71387.0 86414.0 59879.0 68248.0 61735.0 True False 55035.68276462492 98040.89594365112 104057.34000909155 78921.8268743093 78373.06130860651 67643.3400503687 78228.24033681826 58307.239697044824 69245.99788746898 72927.06680600879 0.7546674393339275 1.344369110641004 1.4268685765998448 1.082202127836116 1.0746772733515315 0.9275477955298109 1.0726914404073178 0.7995281073369679 0.9495239685378858 1.0 16.154166748276964 -6.445169417512507 1.965481188284937 0.9432622909049052 1.1903169049106757 0.21585395384425254 0.17885097933530492 0.4690712099460144 3.604216703195907 0.06588083891137758 0.07537063326194052 3.5878194713665215e-07 6.445169417512507 0.24705461400577045 HGGSPQPLATTPLSQEPVNPPS(ph)EASPTR ddPTM_PC-9_Lapatinib_30min_R1 1 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 HGGSPQPLATTPLSQEPVNPPS(0.592)EAS(0.353)PT(0.055)R 164.39 1.0364000000000001e-13 29331000.0 21085.0 25505.0 34919.0 22796.0 37741.0 38315.0 31349.0 33378.0 38943.0 30140.0 True False 20784.324033484565 25445.944739522543 32048.094611237986 24472.49388522674 35521.14858166088 36676.356766627374 32972.09782816495 34928.86373237972 34556.82925202998 35349.65884097446 0.5879639214337498 0.7198356525587644 0.9066026564898678 0.6922978803082595 1.0048512417462891 1.0375307137084762 0.9327416136176785 0.9880962045351628 0.9775717895182203 1.0 15.10940867122318 -4.138249654878343 0.45407758332622566 1.003891393066018 1.45211556533684e-21 0.7406420172904133 0.07646586732413414 4.5198028001375565 0.4650787544946632 0.05247246688860717 2.750266092546304 7.273615593767852e-05 4.138249654878343 -1.003891393066018 HGGSPQPLATTPLSQEPVNPPSEAS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 2 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 HGGSPQPLATTPLSQEPVNPPS(0.366)EAS(0.466)PT(0.167)R;HGGSPQPLATTPLSQEPVNPPS(0.127)EAS(0.719)PT(0.153)R 149.3 1.6271e-12 47328000.0 20827.0 26208.0 43563.0 43545.0 46796.0 49620.0 39606.0 62329.0 46688.0 39558.0 True False 27449.55277148847 34679.22347462684 42985.32615644145 33506.37301354355 40299.18315775775 46517.25355592266 43130.857273011454 52697.48522793292 49155.83236455892 38173.08646051809 0.7190813035220291 0.9084731335647981 1.1260636784217224 0.8777485951574479 1.05569622198191 1.2185876980116561 1.1298760795153706 1.3804879331001234 1.287709140716199 1.0 15.220268219004767 -4.869810079082019 0.454611694523029 1.2363861984538493 0.4574909037993998 0.5622363247607317 0.1262158925183304 3.4526267104273396 0.5891234728304289 0.09386076309826784 1.4458693982657504 1.3495529253076098e-05 4.869810079082019 -0.7788952946544496 HGGSPQPLATTPLSQEPVNPPSEAS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 HGGSPQPLATTPLSQEPVNPPS(0.117)EAS(0.822)PT(0.061)R 170.07 3.7076999999999996e-14 23963000.0 22976.0 42673.0 44412.0 39851.0 44650.0 35964.0 37661.0 30026.0 32007.0 29480.0 True False 26865.38300331483 46909.29342396785 45470.95051344792 37618.2776686852 35901.153022706894 34077.98452899637 34093.47743797197 29237.849315176718 32475.04182370502 34824.490636448405 0.7714508529005354 1.3470202310689683 1.30571760512289 1.0802247780564156 1.0309168164869473 0.9785637609105267 0.9790086463544326 0.839577228003314 0.9325345821344369 1.0 15.08781463082123 -6.4884974883366695 1.6584338953942799 0.9313236841221862 1.1590534854379302 0.23803434889739328 0.1506052779843251 0.4786385793930972 2.660063339446488 0.058585119813425075 0.065921218357561 3.247151200933474e-07 6.4884974883366695 0.22772980131574394 HGGSPQPLATTPLSQEPVNPPSEAS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 3 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 HGGSPQPLATTPLSQEPVNPPS(0.027)EAS(0.941)PT(0.032)R;HGGSPQPLATTPLSQEPVNPPS(0.282)EAS(0.575)PT(0.142)R;HGGSPQPLATTPLSQEPVNPPS(0.373)EAS(0.593)PT(0.034)R 233.8 1.4685999999999997e-65 79713000.0 68422.0 74597.0 94558.0 82731.0 108251.0 115577.0 103596.0 113383.0 109154.0 82428.0 True False 67446.28973294205 74424.27522972603 86783.80624443546 88815.31372252568 101883.88900965457 110634.04113314621 108959.69398087899 118651.18810499154 96859.92707742282 96675.56997159374 0.6976559822999735 0.7698353912120113 0.8976808336370318 0.918694492813669 1.0538742004788924 1.144384679248893 1.1270654417956336 1.2273130444418887 1.0019069668364329 1.0 16.560863744601185 -5.70989996299284 0.9466616057956688 1.1190950407978035 0.6892004455397371 0.811330970045678 0.06873693900039322 0.28173282465855026 0.45706526143968323 0.02725807555544137 0.09267008929414483 1.950293785950995e-06 5.70989996299284 -0.4298945952580664 HGGVCAPAAVAT(ph)SPPGAIPK ddPTM_PC-9_AZD4547_30min_R2 3 HGGVCAPAAVATSPPGAIPK 20 0 A0A494BZT8;Q9Y6A5;E7EMT0 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 HGGVCAPAAVAT(0.572)S(0.428)PPGAIPK;HGGVCAPAAVAT(0.576)S(0.424)PPGAIPK;HGGVCAPAAVAT(0.573)S(0.427)PPGAIPK 110.04 0.00018532 72640700.0 402297.0 353736.0 331605.0 508296.0 428847.0 457246.0 395727.0 434514.0 407710.0 480863.0 True False 530219.077702574 468074.2443154987 327207.70103314216 391116.2102949164 369308.996488053 428654.3353371905 430945.9363752204 367369.8454383993 429260.7182435383 464028.13273330685 1.1426442499927247 1.0087195393916284 0.7051462572016077 0.8428717629491326 0.7958763067072655 0.9237679896954719 0.9287064856106474 0.7916973552324241 0.9250747701761638 1.0 18.823852749023423 -5.0186953723590015 5.674114416414631 0.8573220604433037 1.1156987321823688 0.5427466673879806 0.0817343259722233 0.10250204305077341 11.733775077370968 0.020305433426434802 0.06541691408417992 9.578657124792162e-06 5.0186953723590015 0.2583766717390651 HGGVCAPAAVAT(ph)SPPGAIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HGGVCAPAAVATSPPGAIPK 20 0 A0A494BZT8;Q9Y6A5;E7EMT0 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 HGGVCAPAAVAT(0.548)S(0.452)PPGAIPK 82.259 0.0023160999999999998 19440000.0 141380.0 120050.0 115820.0 118570.0 134560.0 104480.0 119060.0 115470.0 130310.0 80429.0 True False 165312.84161771627 131967.77061719002 118581.58804979603 111926.90730912673 108193.9339470422 99000.88487347167 107781.7748802459 112439.03485057823 132215.53722770038 95010.14102438642 1.7399494394528383 1.3889861565758292 1.2480940115577712 1.1780522173985433 1.1387619550977393 1.0420033462329137 1.1344239016820463 1.1834424582289411 1.3915939477846304 1.0 16.535793889043212 -4.489146571255251 1.1133023519726253 1.1523995358446582 2.3784833582915734 0.7726213108369564 0.09774940264857304 1.364902557993794 0.9162091245426515 0.030818154954894324 2.2938907970824536 3.2423017353711246e-05 4.489146571255251 1.2260838224469153 HGGVCAPAAVAT(ph)SPPGAIPK ddPTM_PC-9_Lapatinib_30min_R1 3 HGGVCAPAAVATSPPGAIPK 20 0 A0A494BZT8;Q9Y6A5;E7EMT0 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 HGGVCAPAAVAT(0.611)S(0.389)PPGAIPK;HGGVCAPAAVAT(0.5)S(0.5)PPGAIPK;HGGVCAPAAVAT(0.5)S(0.5)PPGAIPK 227.0 1.5250999999999998e-35 56393700.0 264990.0 234100.0 274449.0 266598.0 272188.0 237845.0 219468.0 203780.0 260764.0 205936.0 True False 261211.19400678616 233557.95583306142 251884.86262377654 286204.50626485696 256178.4369821972 227672.9237937749 230830.97917482865 213248.36273546476 231394.01235334593 241531.76320752877 1.0814776099752497 0.9669865061697244 1.042864339160859 1.1849559762412885 1.0606407769320332 0.9426210481399663 0.9556961623159029 0.8828998716505773 0.9580272560446955 1.0 17.881853401008065 -6.755796013336496 6.564694633350105 0.9406429432829495 1.0674097099378608 0.525155652190481 0.05665682255020374 0.12220029292680414 23.369495547262947 0.020617714256389235 0.01952509024911978 1.7547044871353672e-07 6.755796013336496 0.12676676665491127 HGGVCAPAAVATS(ph)PPGAIPK ddPTM_PC-9_AZD4547_30min_R2 2 HGGVCAPAAVATSPPGAIPK 20 0 A0A494BZT8;Q9Y6A5;E7EMT0 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 HGGVCAPAAVAT(0.247)S(0.753)PPGAIPK;HGGVCAPAAVAT(0.025)S(0.975)PPGAIPK 179.74 1.1816e-09 24835000.0 32817.0 30048.0 32366.0 39858.0 39188.0 36477.0 34067.0 36308.0 31737.0 33832.0 True False 43252.12336399562 39760.42837933406 31936.805692431295 30669.35389996139 33747.42263411852 34196.08742360724 37098.89700347626 30697.432874838174 33414.553027630354 32647.55197765935 1.3248198025258664 1.2178685987403293 0.9782297219186781 0.9394074606558054 1.0336892229228032 1.047431900774905 1.1363454457125286 0.9402675243719456 1.0234933709729863 1.0 14.994687197290567 -5.1042281429123335 3.500723275892154 1.0143099478525113 1.3090395321648716 0.7872193217526011 0.05497882854363237 0.10868924890545437 2.390622396048008 0.015283450829216021 0.05283639071825757 7.866324485831797e-06 5.1042281429123335 0.2947295843123603 HGGVCAPAAVATS(ph)PPGAIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HGGVCAPAAVATSPPGAIPK 20 0 A0A494BZT8;Q9Y6A5;E7EMT0 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 HGGVCAPAAVAT(0.176)S(0.824)PPGAIPK;HGGVCAPAAVAT(0.029)S(0.971)PPGAIPK;HGGVCAPAAVAT(0.201)S(0.799)PPGAIPK 197.15 1.5324000000000002e-15 83246000.0 396280.0 348248.0 316986.0 388235.0 379059.0 407989.0 438938.0 383020.0 371329.0 269267.0 True False 463362.3771132321 382819.759949147 324544.148416099 366483.45162485185 304785.11004779994 386593.33861641336 397358.61500407616 372966.1308432351 376758.98413954914 318082.9755836003 1.4567342884764 1.2035216887881892 1.0203128533384855 1.1521630510166385 0.9581937212722492 1.2153851928325123 1.2492294322732158 1.1725435168573182 1.184467617131327 1.0 18.279043632550078 -4.801102331921761 3.558528742511534 1.1278053859708044 1.4879283715231728 0.5449768496552442 0.09239537025246171 0.2119018480760858 4.521142547208476 0.023982418401232324 0.19894317016901264 1.580875496916875e-05 4.801102331921761 0.36012298555236844 HGGVCAPAAVATS(ph)PPGAIPK ddPTM_PC-9_Lapatinib_30min_R1 1 HGGVCAPAAVATSPPGAIPK 20 0 A0A494BZT8;Q9Y6A5;E7EMT0 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 HGGVCAPAAVAT(0.145)S(0.855)PPGAIPK 114.54 2.0844000000000002e-05 5878500.0 35350.0 30851.0 36651.0 34399.0 33581.0 32517.0 26718.0 28370.0 38074.0 25111.0 True False 34845.90251760393 30779.566404979774 33637.69625695133 36928.8172117001 31605.831602786217 31126.323710829267 28101.327307821986 29688.17376977688 33785.70518300566 29451.40289169571 1.183166134589442 1.045096782593625 1.142142409332766 1.2538899198622815 1.0731519893640782 1.0568706633532159 0.9541592097042549 1.0080393752023247 1.147167939919496 1.0 14.846048736752456 -6.497655363157166 10.637589897556287 1.0327788443401054 1.1492249691378362 0.42952832592601287 0.066732817496101 0.6972952609261099 290.8679641058851 0.021697364790361853 0.02404560470567895 3.179396097591521e-07 6.497655363157166 0.11644612479773087 HGINCFINR ddPTM_PC-9_Lapatinib_30min_R1 1 HGINCFINR 9 0 P78371;P78371-2;F5GWF6;F8VQ14 P78371 CCT2 T-complex protein 1 subunit beta 0 112.41 0.00057923 0.0 26875.0 21264.0 35906.0 26295.0 29420.0 29639.0 24190.0 26473.0 37777.0 21333.0 False True 26491.757571728587 21214.76451445626 32953.94728116817 28228.822017548577 27689.573441945453 28371.409061883573 25442.43983742098 27703.032224437928 33522.156450554314 25020.38062556428 1.0588071367971494 0.8478993518100328 1.3170841712734722 1.1282331168338067 1.1066807438434392 1.1339319527735487 1.0168686167557925 1.10721865662318 1.3397940244083835 1.0 14.610816116392797 -5.247625456960126 24.998873014124094 1.1407988246355543 0.9533532563764372 0.3072356536684214 0.11427879136478623 954.5979129027435 1727516.2010129094 0.028232651204682196 0.07386826297009436 5.654243963379122e-06 5.247625456960126 -0.18744556825911707 HGIVEDWDLMER ddPTM_PC-9_AZD4547_30min_R2 2 HGIVEDWDLMER 12 0 P61158;F8WDR7;B4DXW1 P61158 ACTR3 Actin-related protein 3 0 ; 126.12 0.00018523 9674300.0 24132.8 31702.0 40215.0 42633.0 38551.0 39040.0 34650.0 41985.0 39740.0 38598.0 False True 31806.528406576912 41949.05153360119 39681.72282398581 32804.620523284 33198.859088698155 36598.822628440554 37733.782874055585 35497.18296932027 41840.57526918207 37246.69576831685 0.8539422826771252 1.1262489374771414 1.0653756529388645 0.8807390789061237 0.8913236034466738 0.9826058895557818 1.0130773239260882 0.9530290469286468 1.1233365646563716 1.0 15.18482482632956 -8.243897045313705 24.390584487879707 1.0616683005453251 0.975279861852738 0.15491611939290106 0.08438110696443417 1046.461942106516 1454991.1135249145 0.05882994199229202 0.022119078185203023 5.702994525436366e-09 8.243897045313705 -0.08638843869258717 HGIVEDWDLMER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HGIVEDWDLMER 12 0 P61158;F8WDR7;B4DXW1 P61158 ACTR3 Actin-related protein 3 0 ;; 116.74 0.00044988 7667700.0 35289.0 42199.9 34039.7 44676.0 49529.0 44069.5 42418.9 39774.3 35655.4 30839.8 False True 41262.73071047948 46389.2271825768 34851.33554428114 42172.948561546254 39824.14799690145 41758.41784007909 38400.67470575896 38730.26676935434 36176.79277161036 36430.81161227752 1.1326327601379478 1.2733514607438283 0.95664449958441 1.1576175960717159 1.0931446826037865 1.1462390210929618 1.0540713480239232 1.063118416947425 0.9930273625696125 1.0 15.152871515611888 -1.5228787506314168 0.1175280543822001 0.9466112410361204 1.6692521342832851 0.30936937741967085 0.07451166081491678 119.49171066524713 0.972835624904347 0.5419516158962675 14.095284740151538 0.029999999630360548 1.5228787506314168 0.7226408932471647 HGLAHDEMKS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 HGLAHDEMKSPR 12 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 HGLAHDEMKS(1)PR;HGLAHDEMKS(1)PR 54.199 0.036175 13251800.0 91763.0 89629.0 82589.0 81388.0 101478.0 92882.0 86637.0 91804.0 84540.0 81431.0 True False 90454.44279272671 89421.4695572892 75798.85122275926 87373.54502240913 95509.26355342426 88909.65337851705 91122.63994190338 96069.5489869789 75018.21495433367 95506.23985001304 0.9471050575834639 0.9362892906025866 0.7936533920903693 0.9148464556831488 1.0000316597472163 0.9309303090368175 0.9541014292365206 1.0058981396173747 0.7854797243839291 1.0 16.543307373499786 -6.00427605422818 24.96893904084933 0.9470514478022114 0.8896610398006208 0.10528427838097465 0.07083775667511323 399.3925440439221 2332184.530550028 0.019758450610561806 0.028530587375010154 9.902023342330686e-07 6.00427605422818 -0.057390408001590565 HGLEVIYMIEPIDEYCVQQLK ddPTM_PC-9_Lapatinib_30min_R1 1 HGLEVIYMIEPIDEYCVQQLK 21 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 90.71799999999999 0.00026846 0.0 5440.8 4961.0 4926.5 4762.5 5100.4 5087.1 3492.4 4918.7 6056.6 3850.6 False True 5363.213194279481 4949.513109302932 4521.462186839941 5112.7501372342695 4800.404499772214 4869.536591609299 3673.219383555561 5147.240758597162 5374.441929174562 4516.171079398017 1.187557579194801 1.095953413253485 1.0011715914541104 1.1320984186267304 1.0629368142563995 1.0782444920705667 0.8133481480168334 1.1397355565376994 1.1900439187726581 1.0 12.140884423280571 -6.731447386785212 3.166564086222163 1.037383909347126 1.0950222889699937 0.06554352239903782 0.10287163417994519 0.8499533182739469 17.55791273346034 0.03888325469165447 0.0368495617154986 1.855891630412533e-07 6.731447386785212 0.057638379622867664 HGLLLPAS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 2 HGLLLPASPVR 11 0 Q96E09 Q96E09 FAM122A Protein FAM122A 1 HGLLLPAS(1)PVR;HGLLLPAS(1)PVR 83.499 0.0072342 47327000.0 188050.0 206833.0 245580.0 365180.0 326780.0 269840.0 223657.0 301420.0 254580.0 283830.0 True False 247845.98831701218 273687.7224102371 242323.44874087855 280993.39297475753 281412.23763338954 252966.86214288912 243562.0397189803 254842.46494253917 268036.5790646293 273893.1980911279 0.9049001218151848 0.9992497963354956 0.8847370085483259 1.0259232245748113 1.0274524507898146 0.9235967300609038 0.8892591762645524 0.9304446649958416 0.9786171432247468 1.0 18.063253912798295 -5.11080488625811 0.0025439127841220674 1.9002744998115693 3.499218023179956e-08 0.031663491608873384 0.052217293000721816 723107.7753754874 320.7646521210478 117832.17021020781 121795.83144644952 7.748098153219113e-06 5.11080488625811 -1.900274464819389 HGLLLPAS(ph)PVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HGLLLPASPVR 11 0 Q96E09 Q96E09 FAM122A Protein FAM122A 1 HGLLLPAS(1)PVR;HGLLLPAS(1)PVR 101.43 0.0021175 19969400.0 156954.0 165007.0 158735.0 205893.0 223280.0 200001.0 196299.0 212625.0 184388.0 152840.0 True False 183523.2122171949 181387.8044667277 162519.8444058401 194357.4827241128 179529.88682889155 189512.5954783617 177704.13763831195 207043.81904480996 187084.3256721754 180548.68211922576 1.0164749477152366 1.0046476237746662 0.9001441744034427 1.0764824225954104 0.99435722665834 1.049648179393614 0.9842450000325375 1.146747883255598 1.0361987884720965 1.0 17.46202836408367 -6.567180925473005 0.9555566506060961 1.0552517954536518 0.9860924219636034 0.13274798779809316 0.05690486901081903 0.9617068532658062 1.9083942565976073 0.030327717520754572 0.0341590560330549 2.7090628112401837e-07 6.567180925473005 -0.06915937349004841 HGLLLPAS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 2 HGLLLPASPVR 11 0 Q96E09 Q96E09 FAM122A Protein FAM122A 1 HGLLLPAS(1)PVR;HGLLLPAS(1)PVR 84.46799999999999 0.006795999999999999 26664000.0 244320.0 217034.0 230132.0 215379.0 237380.0 229249.0 215591.0 202729.0 229610.0 195096.0 True False 240835.9519971992 216531.47110752875 211211.4352952099 231218.6901432815 223417.77510703632 219444.5546755204 226753.24708513534 212148.52943860018 203748.90389950975 228818.08365092022 1.0525214972283974 0.9463040143184852 0.9230539471584307 1.0104913320401006 0.9763991182090201 0.9590350167004289 0.9909760778831845 0.9271493146592786 0.8904405659228601 1.0 17.803841548242595 -7.769257645389398 24.917975355158163 0.931596188847971 0.9766010174416663 0.15463568820637286 0.0419589803697341 290.1482933281221 924726.9948782838 0.02180809860518019 0.010783030179429682 1.7011490015977513e-08 7.769257645389398 0.045004828593695256 HGLLVPNNTTDQELQHIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HGLLVPNNTTDQELQHIR 18 0 P56537;B7ZBH1 P56537 EIF6 Eukaryotic translation initiation factor 6 0 ; 87.287 0.00069724 7962100.0 94938.0 84110.0 95422.0 103972.0 114958.0 106375.0 110214.0 114846.0 105187.0 79614.0 False True 111009.12828902765 92459.88493637524 97697.22236995038 98146.78592177216 92432.80513290799 100796.50773751497 99773.73203973976 111831.41418939526 106725.16088074693 94047.38797592257 1.1803531249315242 0.9831201793721932 1.0388084610596757 1.0435886422161889 0.982832241513949 1.0717629687208354 1.0608878586323227 1.189096439531374 1.1348019671537295 1.0 16.52110025517976 -7.547563291149723 23.860356000153377 1.1221680625616481 1.045099873436744 0.11488277924537238 0.06806542994834579 211.65604165348907 204584.81551731034 0.03053705260759968 0.017632047732692013 2.8342405602807057e-08 7.547563291149723 -0.0770681891249041 HGLLVPNNTTDQELQHIR ddPTM_PC-9_Lapatinib_30min_R1 2 HGLLVPNNTTDQELQHIR 18 0 P56537;B7ZBH1 P56537 EIF6 Eukaryotic translation initiation factor 6 0 ; 116.0 5.2586999999999996e-05 6504700.0 36863.0 32809.0 28649.0 27251.0 28763.4 31842.0 32232.0 25445.0 32139.0 27119.0 False True 36337.326860153735 32733.032776278953 26293.58980833808 29255.129446671108 27071.59336302018 30480.19188732741 33900.81524761278 26627.267591539417 28519.167381326355 31806.483016203907 1.142450325037244 1.0291308460480528 0.8266739140867204 0.919785108959296 0.8511344479434736 0.958301232858697 1.0658460801950944 0.8371647873791666 0.8966463650444213 1.0 14.957033235061113 -4.989521809383333 4.139813111596922 0.9177155976044198 1.1293055178194469 0.49727063127382165 0.07114742300461875 0.1652307536571596 6.669281251841568 0.01853540881945937 0.07642278541761661 1.0244203347182814e-05 4.989521809383333 0.2115899202150271 HGLQLGAQS(ph)PGR ddPTM_PC-9_AZD4547_30min_R2 4 HGLQLGAQSPGR 12 0 Q8N1G0;A6PVV7 Q8N1G0 ZNF687 Zinc finger protein 687 1 HGLQLGAQS(1)PGR;HGLQLGAQS(1)PGR;HGLQLGAQS(1)PGR;HGLQLGAQS(1)PGR 125.33 0.00016783 181835000.0 935950.0 1023120.0 1211689.0 1595570.0 1296463.0 1254395.0 1053924.0 1439761.0 1123251.0 1223430.0 True False 1233562.6310306182 1353823.5317979313 1195621.2121564716 1227735.9878107626 1116471.4910303452 1175957.482351504 1147721.1942786803 1217279.019866416 1182623.7546976358 1180598.0880831094 1.044862467152988 1.1467268543489524 1.0127250113523008 1.0399271354099762 0.945682957053671 0.9960692755829038 0.9721523402957479 1.0310697875539203 1.0017157969633979 1.0 20.171086479854978 -5.4013432062289555 5.7460078558466625 0.9981703732202628 1.0952028315186277 0.5631473843902466 0.033935419216531926 0.14950538613245531 6.358293909760476 0.00871062165845799 0.018457053934039732 3.968777882542946e-06 5.4013432062289555 0.09703245829836493 HGLQLGAQS(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 HGLQLGAQSPGR 12 0 Q8N1G0;A6PVV7 Q8N1G0 ZNF687 Zinc finger protein 687 1 HGLQLGAQS(1)PGR;HGLQLGAQS(1)PGR;HGLQLGAQS(1)PGR;HGLQLGAQS(1)PGR;HGLQLGAQS(1)PGR 127.79 0.00022374 86360900.0 405781.0 404764.0 461917.0 537420.0 538360.0 437840.0 514307.0 432348.0 413549.0 389478.0 True False 474471.7087599281 444946.29492791503 472930.8531099788 507310.0997391476 432872.22264959716 414878.899626731 465588.1176997691 420999.32311057096 419596.3717671574 460087.2782938474 1.0312645690170414 0.9670910627607874 1.027915518255057 1.1026388332675003 0.9408480587744732 0.9017395594271511 1.0119560780431065 0.915042303868459 0.9119929882068389 1.0 18.81154803999312 -6.307974006469346 24.717870428831617 0.9436737075521219 1.0272669203165277 0.4547373094594467 0.04554500987562748 347.52749360499763 184595.83923855005 0.014320577169399239 0.016238043195045737 4.92068986268657e-07 6.307974006469346 0.08359321276440579 HGLQLGAQS(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 4 HGLQLGAQSPGR 12 0 Q8N1G0;A6PVV7 Q8N1G0 ZNF687 Zinc finger protein 687 1 HGLQLGAQS(1)PGR;HGLQLGAQS(1)PGR;HGLQLGAQS(1)PGR;HGLQLGAQS(1)PGR 127.07 0.00013884 208961000.0 1248750.0 1400040.0 1522940.0 1327810.0 1378340.0 1450260.0 1238810.0 1382620.0 1341220.0 1152680.0 True False 1230942.5960072966 1396798.2933982003 1397729.7519184027 1425461.576844313 1297268.7511207038 1388235.760521179 1302949.520256118 1446861.5727024626 1190157.6799272683 1351919.2021504433 0.9105149139455123 1.033196578002864 1.033885567787698 1.054398498502639 0.959575652936352 1.02686296511875 0.963777656374411 1.0702278437949533 0.8803467529968747 1.0 20.36657750042643 -8.262865405883444 24.999993752625187 0.9401733858651302 1.0076338640601852 0.19732985794225677 0.053517103442271896 201.4207425489519 3530964.9433318153 0.04061998922722068 0.012667390441911508 5.459270255267158e-09 8.262865405883444 0.06746047819505496 HGLTSGS(ph)ASPPPPALPLYPDPVR ddPTM_PC-9_AZD4547_30min_R2 1 HGLTSGSASPPPPALPLYPDPVR 23 0 Q92610;H0YM74 Q92610 ZNF592 Zinc finger protein 592 1 HGLT(0.003)S(0.012)GS(0.765)AS(0.22)PPPPALPLYPDPVR 134.63 1.0321e-06 15117000.0 2470.8 2453.9 18696.0 27604.0 20001.0 15930.0 12809.0 24214.0 11831.0 20603.0 True False 3256.4630041673663 3247.075186370069 18448.078824250606 21240.324277548643 17224.20639239064 14933.894581738172 13948.976185679023 20472.282682365632 12456.362506534791 19881.695241065136 0.16379201897437926 0.1633198350039748 0.9278926470086197 1.0683356735937333 0.8663348966749314 0.7511378884277732 0.7015989339212768 1.0297050847093085 0.6265241648411596 1.0 14.279153155142108 -5.258525713444155 24.84950717275625 0.8689893078360916 0.16355583381622418 0.8109417950232378 0.13671391996698007 89.63235535590016 764427.7835226029 0.03546774646601419 0.08571810307817533 5.5140955389296525e-06 5.258525713444155 -0.7054334740198674 HGLTSGS(ph)ASPPPPALPLYPDPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HGLTSGSASPPPPALPLYPDPVR 23 0 Q92610;H0YM74 Q92610 ZNF592 Zinc finger protein 592 1 HGLT(0.003)S(0.009)GS(0.969)AS(0.019)PPPPALPLYPDPVR 97.999 4.2655e-06 11324000.0 6667.6 7488.9 16223.0 17197.0 25183.0 18025.0 18918.0 19217.0 18063.0 9959.4 True False 7796.292988897198 8232.348499584106 16609.817846070113 16233.507843426254 20248.571927678113 17079.737268801007 17125.950085540844 18712.574112094557 18327.137203161306 11764.960381432986 0.6626705688869987 0.6997344855131078 1.4118039761768426 1.3798183178793666 1.721091382477891 1.451746263060571 1.455674267511208 1.590534392417167 1.5577729638668822 1.0 13.522208841836573 -5.273158331577298 3.928647496501866 1.4816543892752032 0.6586236681203594 0.7446400323703404 0.1786857519509266 0.0899988088517125 3.2338105711882705 0.04452335876833265 0.11432414497431341 5.331404919948124e-06 5.273158331577298 -0.8230307211548438 HGLTSGSAS(ph)PPPPALPLYPDPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HGLTSGSASPPPPALPLYPDPVR 23 0 Q92610;H0YM74 Q92610 ZNF592 Zinc finger protein 592 1 HGLT(0.002)S(0.008)GS(0.089)AS(0.9)PPPPALPLYPDPVR 68.134 0.00077049 12832000.0 11896.0 10284.0 16703.0 18526.0 27574.0 17995.0 22750.0 24833.0 16895.0 15625.0 True False 13909.7578432901 11304.927555411743 17101.262866480243 17488.048282102383 22171.072641615217 17051.310521612977 20594.955304263345 24181.16006273841 17142.057412800215 18457.688812568056 0.7536023596745646 0.6124779581132653 0.9265116039249612 0.9474668502480422 1.201183575406184 0.9238052875830554 1.1157927470442561 1.310086019343504 0.9287217693868578 1.0 14.171934296162972 -5.5829998586340865 1.731105112275718 1.0870954683697152 0.6760309743532639 0.5963878181384412 0.12255094404483848 0.2413009365164299 1.4209031226065403 0.03638280889056803 0.09607333223420446 2.6121622046762684e-06 5.5829998586340865 -0.4110644940164513 HGLTSGSAS(ph)PPPPALPLYPDPVR ddPTM_PC-9_Lapatinib_30min_R1 2 HGLTSGSASPPPPALPLYPDPVR 23 0 Q92610;H0YM74 Q92610 ZNF592 Zinc finger protein 592 1 HGLT(0.001)S(0.003)GS(0.06)AS(0.936)PPPPALPLYPDPVR;HGLT(0.002)S(0.007)GS(0.222)AS(0.77)PPPPALPLYPDPVR 111.33 4.0693000000000006e-07 23903000.0 25816.0 18585.1 47448.0 26584.0 38479.0 43549.0 28193.0 30807.0 46881.0 23236.9 True False 25447.85910592542 18542.067342815135 43547.00859457658 28539.07604162433 36215.74087262471 41686.5107876773 29652.69559059154 32238.4056864828 41600.768101184236 27253.36720377701 0.9337510082937067 0.6803587683009464 1.5978579185819453 1.0471761462807112 1.3288538110478185 1.52959120522546 1.0880378695547759 1.1829145897984643 1.5264450733786334 1.0 14.734146868084164 -5.247548934823574 24.963615562029645 1.288542986213778 0.8070548436207466 0.4581535329306674 0.20904089011175808 650.8665038099346 1169718.9444314123 0.050423762205350886 0.13190492394473907 5.655240321765678e-06 5.247548934823574 -0.4814881425930314 HGLYEK ddPTM_PC-9_AZD4547_30min_R2 2 HGLYEK 6 0 E7ETK0;A0A2R8Y849;A0A2R8YD14;P62847-2;P62847-3;P62847;P62847-4;A0A2R8Y8A0 E7ETK0 RPS24 40S ribosomal protein S24 0 ; 93.59299999999999 0.028935000000000002 6501200.0 303900.0 202751.0 261010.0 256270.0 254360.0 266720.0 252700.0 219590.0 359460.0 414360.0 False True 400533.8784873172 268286.2957380977 257548.8368590954 197190.91083203143 219046.50457319504 250041.95623610797 275189.8104552341 185657.41117620672 378460.3217478656 399853.3825213679 1.001701863722293 0.6709616761182723 0.6441081859432117 0.4931580410514438 0.5478170603233282 0.6253341028639313 0.6882267913302649 0.464313719207528 0.9464977371490434 1.0 18.60911156672367 -8.377000778654837 6.226073990743528 0.9938898368384413 0.63642109986306 0.47314056601490306 0.14005023963912264 0.20743078545062787 9.487262483003548 0.13652850540818523 0.03541278233591089 4.197582313978156e-09 8.377000778654837 -0.3574687369753814 HGLYEK ddPTM_PC-9_Lapatinib_30min_R1 2 HGLYEK 6 0 E7ETK0;A0A2R8Y849;A0A2R8YD14;P62847-2;P62847-3;P62847;P62847-4;A0A2R8Y8A0 E7ETK0 RPS24 40S ribosomal protein S24 0 ; 87.58200000000001 0.033248 17059900.0 260310.0 285660.0 231780.0 223600.0 312230.0 228130.0 298810.0 381300.0 340670.0 280580.0 False True 256597.93166499247 284998.57182089763 212723.94309667367 240044.28990773344 293865.24526779854 218373.41169700382 314280.9197114408 399016.59000408684 302300.1571858628 329077.8791506498 0.7797483450643108 0.866052049917421 0.6464243164740039 0.7294452320140384 0.892996047094581 0.6635918897393702 0.9550350832532409 1.2125293594147042 0.9186280097771982 1.0 18.328069525170534 -7.465587350352025 5.681743658035737 1.0562089050454946 0.7684707552514933 0.6245448433191969 0.09969693204396907 0.12759929034712544 8.844028871578544 0.041580340867331506 0.027158287268544364 3.423045324375981e-08 7.465587350352025 -0.28773814979400125 HGQEEAAQS(ph)PYR ddPTM_PC-9_AZD4547_30min_R2 1 HGQEEAAQSPYR 12 0 J3KQ72;Q9NRD1 J3KQ72 FBXO6 F-box only protein 6 1 HGQEEAAQS(0.863)PY(0.137)R 96.135 0.0043783 4229600.0 2870.7 3523.9 3318.1 5210.9 5102.8 3901.9 3583.1 3199.8 3433.3 3716.5 True False 3783.5228857306342 4662.931761379635 3274.099825991975 4009.6075126024566 4394.364300739511 3657.9135761760313 3901.9889586155455 2705.3444340891024 3614.777228779132 3586.3864662145606 1.054967979991334 1.3001754845180893 0.9129244315512364 1.1180076520962914 1.2252902307479911 1.0199440608632921 1.0880001347802608 0.7543371188729139 1.0079162585605388 1.0 11.808315244940156 -7.624051599592436 9.672705695065932 0.9111419163138275 1.106601272149579 0.32985051600870463 0.11884327527961387 0.32541069845652504 28.49853249365699 0.054046461850181346 0.031141015950270034 2.376557905177133e-08 7.624051599592436 0.19545935583575158 HGQEEAAQS(ph)PYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HGQEEAAQSPYR 12 0 J3KQ72;Q9NRD1 J3KQ72 FBXO6 F-box only protein 6 1 HGQEEAAQS(1)PYR;HGQEEAAQS(1)PYR;HGQEEAAQS(1)PYR 137.93 6.7901e-05 3979900.0 5073.330000000001 4590.27 5779.33 7842.4 9450.0 8282.36 8257.5 6513.96 6592.87 7147.18 True False 5932.14456616501 5045.961669562414 5917.131145431076 7403.015753403853 7598.340337392609 7848.018461338513 7475.289820877122 6342.9754521111245 6689.278251265357 8442.907156954247 0.7026187136594089 0.5976568942139984 0.7008404848509152 0.8768325430780253 0.8999672975361354 0.9295398273892261 0.8853928726102219 0.7512785980225481 0.7922956070594165 1.0 13.04352413415748 -5.682347987062241 4.060420638149762 0.8701358755457362 0.6502852473570286 0.6614928715560143 0.06903745025917281 0.13662308765079684 4.286434511933296 0.02013105414313243 0.03577488495944976 2.0780309563482736e-06 5.682347987062241 -0.2198506281887076 HGQEEAAQS(ph)PYR ddPTM_PC-9_Lapatinib_30min_R1 2 HGQEEAAQSPYR 12 0 J3KQ72;Q9NRD1 J3KQ72 FBXO6 F-box only protein 6 1 HGQEEAAQS(1)PYR;HGQEEAAQS(1)PYR 142.39 8.1305e-05 4058800.0 6422.299999999999 5822.299999999999 4423.1 3481.16 4997.2 4015.31 3521.79 4095.4 4414.9 3370.5 True False 6330.716824294419 5808.818822071048 4059.4497916597484 3737.176119209334 4703.27452087321 3843.584551444777 3704.131053949185 4285.687234992747 3917.6474710419616 3953.0864340910557 1.6014617767268877 1.469438859716379 1.0269064082817478 0.9453818380949804 1.1897727508087355 0.972299648775209 0.9370225305485602 1.0841369918030055 0.9910351155635071 1.0 11.948763784639057 -5.200514096988743 3.5434997424483554 1.0180083425196373 1.5740489174351373 0.8952701581638082 0.07130829916261419 0.06720478968294594 1.6742519897411978 0.018807768253011153 0.05720322411463853 6.3021088931831515e-06 5.200514096988743 0.5560405749155 HGRDDS(ph)FDSLDSFGSR ddPTM_PC-9_AZD4547_30min_R2 1 HGRDDSFDSLDSFGSR 16 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 HGRDDS(0.848)FDS(0.148)LDS(0.002)FGS(0.002)R 64.843 0.013916999999999999 6799600.0 5508.6 5019.4 9481.7 17184.0 12192.0 7708.9 11107.0 15013.0 11194.0 10690.0 True False 7260.220214002087 6641.822890283194 9355.966462767277 13222.494290153452 10499.35124923887 7226.861264354133 12095.501482889922 12693.085814419554 11785.69198699607 10315.746353782766 0.7037997993562315 0.6438528694385404 0.9069597236981753 1.2817777634969463 1.0177985081407879 0.700566010107844 1.1725280040890615 1.230457339595697 1.142495325379368 1.0 13.332560584869618 -5.45688697450948 4.1940909324112035 1.0751061941686046 0.6817218465756517 0.5236486326850285 0.15305850543989996 0.18483200125228363 6.308626881453372 0.04438445146555266 0.09501064088120453 3.4923119135310028e-06 5.45688697450948 -0.39338434759295293 HGRDDS(ph)FDSLDSFGSR ddPTM_PC-9_Lapatinib_30min_R1 2 HGRDDSFDSLDSFGSR 16 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 HGRDDS(0.992)FDS(0.008)LDSFGSR;HGRDDS(0.984)FDS(0.015)LDS(0.001)FGSR 71.89399999999999 0.0081245 11751000.0 29350.0 23835.0 28929.0 21283.0 22721.1 29253.0 18036.7 24309.0 31293.0 20899.0 True False 28931.463617869198 23779.811521918033 26550.569289169325 22848.22281800671 21384.689569401315 28001.91738207362 18970.5520717491 25438.48488436751 27768.452810101284 24511.36430383295 1.180328571647277 0.9701545465667727 1.0831942669554913 0.9321481470712683 0.8724397917768003 1.1424054995459734 0.7739492521345535 1.0378241116668312 1.1328807513892243 1.0 14.581163166471294 HGRPGIGATHS(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 1 HGRPGIGATHSSR 13 1 K7EM56;A0A0B4J2B4;S4R417;K7EQJ5;K7ELC2;P62841 K7EM56 RPS15 40S ribosomal protein S15 1 HGRPGIGAT(0.003)HS(0.582)S(0.415)R 55.755 0.032067 369520.0 1269.3 635.57 2336.9 859.28 658.82 922.05 1018.1 2127.7 928.85 633.73 True False 1251.1995492388883 634.0983767143049 2144.7691026948683 922.4743176740499 620.069502889956 882.6160709035306 1070.812236398441 2226.560709550732 824.2331317758795 743.2693861078546 1.6833729097747727 0.8531205355231621 2.8855878404006328 1.2411036091565744 0.8342459873626205 1.187478036093169 1.4406785163126 2.9956308589677865 1.1089292081461786 1.0 9.537741377072695 -7.598120039103898 24.999999840288275 1.8749948129662346 1.4371940899959228 0.008131028853348377 0.7464749692953152 117.07797609410211 38896.044291040926 0.3455163578868982 0.1994839571121238 2.5227833781455593e-08 7.598120039103898 -0.4378007229703118 HGS(ph)DPAFAPGPR ddPTM_PC-9_AZD4547_30min_R2 2 HGSDPAFAPGPR 12 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 HGS(1)DPAFAPGPR;HGS(1)DPAFAPGPR 181.66 0.00034189 154256000.0 266220.0 217010.0 247140.0 371420.0 357350.0 298530.0 292260.0 294600.0 278600.0 292550.0 True False 350872.4222800047 287154.2386381549 243862.7621215924 285794.85738179664 307738.12080999865 279862.87190748914 318270.5738173594 249076.3392345308 293326.2272268275 282307.9135452897 1.2428713664936475 1.0171668056768366 0.8638183714338928 1.012351562493297 1.0900796826605048 0.9913390963537112 1.1273880700701657 0.8822860688054085 1.0390294184217765 1.0 18.10691004485576 -4.766133973904464 5.649136097954445 1.000407063859363 1.252969741237013 0.47126080200590315 0.07649994474877661 0.12390056049629732 13.287858867446422 0.01903711845784774 0.1215459518510589 1.7134286566790705e-05 4.766133973904464 0.25256267737765015 HGS(ph)DPAFAPGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 HGSDPAFAPGPR 12 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 HGS(1)DPAFAPGPR;HGS(1)DPAFAPGPR;HGS(1)DPAFAPGPR;HGS(1)DPAFAPGPR;HGS(1)DPAFAPGPR;HGS(1)DPAFAPGPR 158.06 0.00041276 203925400.0 653597.3 695151.0 588534.0 810217.0 796472.0 617645.5 732925.0 651234.0 656483.0 561065.0 True False 764238.4137548966 764160.9971870913 602566.8825876254 764823.1682489553 640409.0291220902 585255.0826772389 663497.0380825147 634139.7975394591 666082.8219311838 662781.6431119044 1.1530772188659761 1.152960413325856 0.9091484184118958 1.153959492085423 0.966244366870558 0.8830285038211658 1.0010793825961313 0.9567853970155757 1.0049807939818303 1.0 19.33817411960606 -4.644713459449353 0.7360934145482279 0.9716242647525491 1.3327626066249325 0.40988425429151953 0.07376889144089838 3.298175941993052 1.1838501169139461 0.0297748336903727 1.0349010552824192 2.2661389766991e-05 4.644713459449353 0.36113834187238336 HGS(ph)DPAFAPGPR ddPTM_PC-9_Lapatinib_30min_R1 6 HGSDPAFAPGPR 12 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 HGS(1)DPAFAPGPR;HGS(1)DPAFAPGPR;HGS(1)DPAFAPGPR;HGS(1)DPAFAPGPR;HGS(1)DPAFAPGPR;HGS(1)DPAFAPGPR 140.45 7.4667e-05 217667000.0 1179981.0 1041729.0 1016302.0 1110318.0 1048792.0 947617.0 804823.0 831307.0 920853.0 839519.0 True False 1163154.254557985 1039316.9405041375 932745.572599168 1191974.4896322696 987104.1165644065 907089.6299131179 846492.7969108161 869932.558055406 817136.8381280224 984628.7405612502 1.1813125157152868 1.0555419496608582 0.9473068723014239 1.2105826699237214 1.0025140196514528 0.9212504089572541 0.8597075852450793 0.8835132697421912 0.8298933440255304 1.0 19.90922032579106 -6.665181063651578 3.017607443554117 0.8862584093738298 1.0866683237357553 0.5794582785948906 0.07950346776130247 0.18433954555823512 3.3743455847079393 0.027908099303493954 0.027396102596297378 2.161817043023972e-07 6.665181063651578 0.20040991436192546 HGS(ph)FHEDEDPIGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 HGSFHEDEDPIGSPR 15 0 Q96T58 Q96T58 SPEN Msx2-interacting protein 2 HGS(1)FHEDEDPIGS(1)PR 104.35 0.0015986 0.0 18844.0 19418.0 26854.0 24527.0 32612.0 25766.0 21475.0 25460.0 22008.0 19857.0 True False 24836.000020450785 25694.488760313787 26497.898413908104 18872.679088372548 28084.38672409597 24154.847946834005 23386.233397412525 21525.742012597224 23171.297949777505 19161.8124740004 1.2961195635407339 1.3409216270734938 1.3828492711668916 0.9849109583960203 1.4656435429687102 1.2605721916759378 1.220460404209884 1.1233666983122974 1.209243540047026 1.0 14.225946408451406 -9.075412552079431 0.2606094859860132 0.9221749389346254 1.3371398046862264 0.3433866815948986 0.12055396972296592 5.101971185916628 0.7502281619468147 0.6431094455167695 0.2278911524620982 8.405962493927122e-10 9.075412552079431 0.41496486575160096 HGS(ph)FHEDEDPIGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 HGSFHEDEDPIGSPR 15 0 Q96T58 Q96T58 SPEN Msx2-interacting protein 2 HGS(1)FHEDEDPIGS(1)PR 108.25 0.0016832000000000001 4966900.0 21316.0 20646.0 22441.0 15015.0 19089.0 21967.0 18204.0 23387.0 21818.0 16457.0 True False 21012.029931124358 20598.195455486468 20595.987604765094 16119.253188571669 17966.22255041797 21027.522617578074 19146.514047143908 24473.645398441047 19360.627086274562 19301.570522425896 1.0886176286386193 1.067177172528736 1.0670627854264634 0.8351265079617852 0.9308166156501914 1.0894202931904866 0.9919666394451253 1.2679613490521862 1.0030596766092195 1.0 14.236430620448619 HGS(ph)FNTVQASER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HGSFNTVQASER 12 0 F8VSE7;Q96AV8-2;Q96AV8-3;Q96AV8 F8VSE7 E2F7 Transcription factor E2F7 1 HGS(0.997)FNT(0.003)VQASER 75.316 0.011265 3448300.0 17180.0 20567.0 24924.0 20185.0 22905.0 23720.0 22129.0 21337.0 22571.0 19461.0 True False 20088.234679532943 22608.755837432265 25518.282684796355 19054.09989065296 18416.92967491827 22476.08144332647 20032.78091991401 20776.926358420234 22901.058174863185 22989.125246808762 0.8738146607958254 0.9834543765674904 1.1100153838319131 0.8288310097095999 0.8011148522266986 0.9776831959470268 0.871402487256224 0.9037719415315459 0.9961691856040585 1.0 14.488663951038307 -4.300224606405291 0.002490623882184156 1.848740357436638 5.990899401982365e-06 0.014535533930380318 0.08919221318098483 1753001.949629916 595.2509675442893 216353.61843875004 225561.8000610072 5.0092809895379556e-05 4.300224606405291 -1.848734366537236 HGS(ph)FVNKPTR ddPTM_PC-9_Lapatinib_30min_R1 1 HGSFVNKPTR 10 1 P29353-2;P29353-7;P29353;P29353-6;Q5T181;Q5T182 P29353-2 SHC1 SHC-transforming protein 1 1 HGS(1)FVNKPTR 59.155 0.034816 18781000.0 79436.0 80646.0 61364.0 75714.0 79263.0 68827.0 73813.0 54260.0 81061.0 72167.0 True False 78303.22807322188 80459.2691418753 56318.888791890015 81282.26013449997 74600.90617705372 65883.42965357327 77634.67597021729 56781.117685868645 71931.05656982772 84640.96979351716 0.9251220568980213 0.9505948400420838 0.6653856746830848 0.9603181571854528 0.8813805697057074 0.7783869893539361 0.917223374916523 0.6708467285333212 0.8498373393559236 1.0 16.369068537108696 -6.712174083926578 24.95330412686874 0.8273092596451483 0.8735946476853114 0.011535703671257225 0.11171604541911445 443.77154952106474 224772.21853147302 0.03600265736651876 0.0360025871113413 1.9401080428748556e-07 6.712174083926578 0.04628538804016302 HGS(ph)GADSDYENTQSGDPLLGLEGK ddPTM_PC-9_AZD4547_30min_R2 4 HGSGADSDYENTQSGDPLLGLEGK 24 0 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QL89 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 HGS(0.978)GADS(0.022)DYENTQSGDPLLGLEGK;HGS(0.511)GADS(0.237)DY(0.201)ENT(0.05)QS(0.001)GDPLLGLEGK;HGS(0.923)GADS(0.076)DY(0.001)ENTQSGDPLLGLEGK;HGS(0.77)GADS(0.173)DY(0.053)ENT(0.004)QSGDPLLGLEGK 140.03 1.1449999999999999e-07 30136000.0 130922.2 161323.0 172526.0 208183.0 190761.0 229674.0 185498.0 218808.0 195614.0 173989.0 True False 172552.73624906968 213467.50490679254 170238.1925135142 160189.62574528734 164277.12792454523 215312.4484724499 202006.96264275836 184996.2513076347 205953.75668610388 167897.69806813003 1.0277254437344978 1.2714141251666897 1.0139400031823809 0.9540906610898567 0.9784358559691769 1.2824026234420425 1.2031550460018061 1.1018391165349173 1.2266621821255188 1.0 17.35722292503064 -6.7507941161552845 24.99888924266087 1.1716982041924424 1.0542368494531709 0.21524641177613824 0.107654245572836 347.33039961106243 815654.4220894934 0.03691222728400795 0.03655575671838207 1.7750307615488194e-07 6.7507941161552845 -0.11746135473927155 HGS(ph)GADSDYENTQSGDPLLGLEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HGSGADSDYENTQSGDPLLGLEGK 24 0 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QL89 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 HGS(0.977)GADS(0.022)DY(0.001)ENTQSGDPLLGLEGK;HGS(0.987)GADS(0.013)DYENTQSGDPLLGLEGK;HGS(0.891)GADS(0.108)DY(0.001)ENTQSGDPLLGLEGK 128.25 9.910200000000002e-09 20981400.0 62033.0 83385.0 73778.0 102449.0 107423.0 86290.0 110798.0 88610.0 83634.0 73639.0 True False 72533.96169240214 91662.91172773339 75537.14732462326 96709.11467413935 86374.23429245802 81764.80049513666 100302.41133194594 86284.08139005567 84856.98903001683 86989.16777399692 0.8338275160977483 1.053727884440499 0.8683511896662043 1.1117374398315367 0.9929309189031842 0.9399423237105398 1.153044843382542 0.9918945496090604 0.9754891465392609 1.0 16.408548141755638 -4.752611209789132 24.959535417713564 1.0099767553985284 0.833827173231891 0.3182928452210715 0.07720554792794969 406.42005066569504 1148968.5071041754 0.018518813723605428 0.21732125602222682 1.7676195254397714e-05 4.752611209789132 -0.17614958216663734 HGS(ph)GADSDYENTQSGDPLLGLEGK ddPTM_PC-9_Lapatinib_30min_R1 3 HGSGADSDYENTQSGDPLLGLEGK 24 0 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QL89 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 HGS(0.89)GADS(0.102)DY(0.003)ENT(0.004)QSGDPLLGLEGK;HGS(0.735)GADS(0.209)DY(0.043)ENT(0.012)QSGDPLLGLEGK;HGS(0.987)GADS(0.013)DYENTQSGDPLLGLEGK 170.68 1.2744e-10 20751300.0 51725.6 69568.0 73326.0 71832.0 95764.0 94430.0 89020.0 106151.0 95963.0 88445.0 True False 50987.98345868667 69406.91957024515 67297.4193265453 77114.76490452728 90131.34979926808 90391.44902708138 93629.02002179468 111083.16298327777 85154.63640481097 103732.60040444539 0.49153287645242155 0.6690945691097393 0.6487586261614755 0.7433995157150479 0.8688816191616996 0.8713890201793083 0.9025997580003043 1.070860679768685 0.8209052513173257 1.0 16.662509840627735 -5.515190181215221 0.4926282653410449 0.9791039430675446 0.3906868271150419 0.8324625283421078 0.06747737712716802 0.8868905944091865 0.2772008025575457 0.04734549625144195 0.280647093725556 3.0535836303724624e-06 5.515190181215221 -0.5884171159525027 down HGS(ph)GADSDYENTQSGDPLLGLEGKR ddPTM_PC-9_AZD4547_30min_R2 1 HGSGADSDYENTQSGDPLLGLEGKR 25 1 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QL89 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 HGS(0.98)GADS(0.015)DY(0.004)ENT(0.001)QSGDPLLGLEGKR 61.751000000000005 0.022971000000000002 0.0 3553.5 3302.1 7548.2 15180.0 10165.0 5210.3 5808.0 8633.8 1926.9 10127.0 True False 4683.439082608356 4369.439248915039 7448.105936093736 11680.48552866209 8753.765210672014 4884.499117340262 6324.90074841313 7299.644594986721 2028.7520001556848 9772.456812418903 0.4792488902746146 0.4471177855053119 0.7621528627917428 1.1952455511308528 0.8957589047155134 0.49982304461381794 0.6472170580867038 0.7469610493146702 0.20759897322621404 1.0 13.254505588464527 -6.7672116537594444 24.990811804819035 0.6061861745184762 0.7635048977087121 0.05754702403814571 0.27047561971548933 445.32404836967675 1927998.5520555477 0.09960023898827211 0.09021066687994321 1.7091821408137806e-07 6.7672116537594444 0.15731872319023588 HGS(ph)GPPSSGGGLYR ddPTM_PC-9_AZD4547_30min_R2 1 HGSGPPSSGGGLYR 14 0 Q9HC52 Q9HC52 CBX8 Chromobox protein homolog 8 1 HGS(0.998)GPPS(0.002)SGGGLYR 61.532 0.029292000000000002 9675000.0 0.0 17477.0 0.0 42764.0 36231.0 0.0 17211.0 17778.0 17541.0 21194.0 True False 0.0 23126.098468637567 0.0 32905.420497213825 31200.951042583158 0.0 18742.745657875068 15030.818597798632 18468.18144933877 20452.004510951523 0.0 1.1307497246176597 0.0 1.608909311534418 1.5255693409355473 0.0 0.9164258519422294 0.734931316377816 0.903001045176258 1.0 14.319954628891846 -5.743075982895575 24.99976704136745 0.9268101306489717 0.45230024413596664 0.20769842986874387 0.5094157585644885 485.0547337422246 660344.1045709242 0.14023897101294655 0.24231941726744624 1.8068579757551275e-06 5.743075982895575 -0.474509886513005 HGS(ph)GPPSSGGGLYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HGSGPPSSGGGLYR 14 0 Q9HC52 Q9HC52 CBX8 Chromobox protein homolog 8 1 HGS(0.995)GPPS(0.004)S(0.001)GGGLYR 63.16 0.045545999999999996 4712900.0 9196.7 9137.5 16699.0 17284.0 20427.0 21617.0 22098.0 17878.0 20576.0 18309.0 True False 10753.519666895261 10044.61061236628 17097.167491310174 16315.633515484044 16424.47598644644 20483.36646544641 20004.71746433457 17408.72144330678 20876.885074032394 21628.27676603574 0.4971972470678847 0.464420292056738 0.7905006800245383 0.7543658559569352 0.7593982712593562 0.9470641922620827 0.9249334878009909 0.8049056164587649 0.9652588275926216 1.0 14.400631102633344 -4.60633648918877 0.4539618881776739 0.9426704698623786 1.5488829147215743e-13 0.8289159203930447 0.07304280578908791 2.301663232298846 0.32760379468695183 0.051443610189628064 1.2102452023097943 2.4755033068501102e-05 4.60633648918877 -0.9426704698622237 down HGS(ph)GPPSSGGGLYR ddPTM_PC-9_Lapatinib_30min_R1 1 HGSGPPSSGGGLYR 14 0 Q9HC52 Q9HC52 CBX8 Chromobox protein homolog 8 1 HGS(0.978)GPPS(0.017)S(0.005)GGGLYR 67.01899999999999 0.035283999999999996 4143200.0 6468.5 6457.8 4836.7 3919.0 7844.9 7670.3 6041.0 8634.6 5881.0 1577.1 True False 6376.25800382238 6442.8473608660515 4439.045196201918 4207.216333400755 7383.478405666818 7342.259149342608 6353.773421159987 9035.795038157055 5218.619850324535 1849.699633646344 3.447185633730572 3.4831857257630303 2.3998735337645893 2.2745402858230546 3.9917175044856568 3.96943320730874 3.435029831646064 4.885006664754883 2.8213336670435414 1.0 10.853075300143663 -6.273378591242449 24.75837155692637 3.579851593891425 2.9069581663103885 0.015696155179848792 1.0275098922191561 1676.262696295543 3476062.4387986753 0.304892290487311 0.34842713581533435 5.328701694877384e-07 6.273378591242449 -0.6728934275810365 HGS(ph)ILNR ddPTM_PC-9_Lapatinib_30min_R1 1 HGSILNR 7 0 Q9NZN5-2;Q9NZN5 Q9NZN5-2 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 HGS(1)ILNR 64.711 0.033264 2266600.0 12139.0 8071.7 9888.3 10245.0 6588.8 6437.8 6545.4 6670.5 11851.0 9473.0 True False 11965.895633980033 8053.010474573773 9075.322143941825 10998.451476318132 6201.259738079206 6162.4703012447835 6884.288785111834 6980.435781857484 10516.21558343752 11110.395428020931 1.0769999782187312 0.7248176292865066 0.8168316062858971 0.9899243953621605 0.5581493276503321 0.5546580534571027 0.6196259016802714 0.6282796887905989 0.9465203692854296 1.0 13.439622543881562 -1.522878764232526 0.8870417188153725 0.7225846607732964 147.53391409655703 0.20639893060932057 0.16907307024055251 1268.9662021492622 2.9798390547547537 0.058290658683223924 376844.32283541485 0.029999998690829224 1.522878764232526 146.81132943578373 HGS(ph)PEFCGILGER ddPTM_PC-9_AZD4547_30min_R2 2 HGSPEFCGILGER 13 0 Q15464 Q15464 SHB SH2 domain-containing adapter protein B 1 HGS(1)PEFCGILGER;HGS(1)PEFCGILGER 140.96 4.2548999999999995e-05 10606800.0 38565.0 36029.0 41767.0 50724.0 43170.0 38671.0 42462.0 48859.0 41535.0 52799.0 True False 50827.867798168365 47674.66966450438 41213.142289926975 39030.365477987856 37176.59066844177 36252.896256773165 46241.03574020631 41308.964218125955 43730.45530461693 50950.52308076486 0.9975926590115264 0.9357052053996046 0.8088855579480008 0.7660444509297457 0.7296606280078977 0.7115313850518558 0.9075674388446758 0.8107662438056726 0.8582925681704396 1.0 15.63680933736648 -5.131049253203926 3.085192851979618 0.8104675995666721 0.9895082538264727 0.3302030534048178 0.08138039196258615 0.2751121110716871 4.800269723804984 0.021325547012216204 0.07736271082066425 7.395214014070791e-06 5.131049253203926 0.17904065425980054 HGS(ph)PEFCGILGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HGSPEFCGILGER 13 0 Q15464 Q15464 SHB SH2 domain-containing adapter protein B 1 HGS(1)PEFCGILGER;HGS(1)PEFCGILGER 140.96 4.2548999999999995e-05 7303700.0 25402.0 25517.0 24851.0 33848.0 35459.0 30188.0 30533.0 29183.0 21924.9 24426.6 True False 29702.05688763071 28050.15912402193 25443.542087942333 31951.606296696606 28511.06349456133 28604.888137063244 27640.69320022298 28416.97717194439 22245.510184664323 28854.94921914078 1.0293574479045697 0.972109114141674 0.8817739339864958 1.10731805674091 0.9880822620075402 0.9913338581822331 0.9579186222198468 0.9848215970206641 0.7709426211676671 1.0 14.816531171610109 -8.05964477490276 24.999384392968867 0.8829412916981835 0.9881085795384427 0.23908060456787816 0.07392136928127348 342.04534138522 143361.70915568093 0.047293489185628625 0.017875316604634154 8.716762738679942e-09 8.05964477490276 0.1051672878402592 HGS(ph)PEFCGILGER ddPTM_PC-9_Lapatinib_30min_R1 2 HGSPEFCGILGER 13 0 Q15464 Q15464 SHB SH2 domain-containing adapter protein B 1 HGS(1)PEFCGILGER;HGS(1)PEFCGILGER 115.56 0.00016297 10248200.0 26139.0 35193.0 37207.0 35355.0 34333.0 35549.0 31042.0 31882.0 36097.0 27845.0 True False 25766.253066694477 35111.51277075149 34147.9840831734 37955.12464082258 32313.600441275074 34028.65213876645 32649.20287032747 33363.354110963235 32031.37574173861 32657.971148869696 0.7889728651311597 1.0751284153782075 1.0456247856767207 1.1622009361146801 0.9894552326589785 1.0419707943169088 0.9997315118412514 1.0215991054336502 0.9808134006771339 1.0 14.995147546922366 -4.7561903430005845 24.999902815223393 1.0378173471591818 0.7889724769935273 0.6797276013465192 0.05066919492377782 98.68828527311126 469977.38695430313 0.012882266306703442 0.1067566270054634 1.7531119778462453e-05 4.7561903430005845 -0.24884487016565449 HGS(ph)SDISSPR ddPTM_PC-9_AZD4547_30min_R2 2 HGSSDISSPR 10 0 Q9BRD0 Q9BRD0 BUD13 BUD13 homolog 1 HGS(0.963)S(0.037)DISSPR;HGS(0.993)S(0.005)DIS(0.002)SPR 98.898 0.012512 0.0 6851.3 5916.299999999999 10232.2 14852.400000000001 14547.3 10288.7 9398.3 13353.8 8634.8 11460.1 True False 9029.870884107115 7828.628275447757 10096.514342399292 11428.408647292546 12527.658499676243 9645.345962531666 10234.730493080424 11290.277049796565 9091.217899706418 11058.88538718296 0.8165263105604265 0.7079039162953068 0.9129775731377923 1.0334141504475538 1.1328138470623417 0.8721806606035036 0.925475772173413 1.0209235971359087 0.8220736160484102 1.0 13.43291836481307 -5.422626083935096 4.58595499899001 0.9739406228060641 0.7648297069411967 0.48148293274048615 0.08586468582419941 0.18464880733779468 6.339027082074758 0.023300303828204246 0.05023918146664268 3.7789741058036265e-06 5.422626083935096 -0.2091109158648674 HGS(ph)SDISSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HGSSDISSPR 10 0 Q9BRD0 Q9BRD0 BUD13 BUD13 homolog 1 HGS(0.954)S(0.046)DISSPR 91.70100000000001 0.007903199999999999 1334500.0 1886.9 5573.9 7290.0 6820.0 6336.3 6881.1 6168.6 5995.9 6892.6 5007.8 True False 2206.314902026233 6127.239955378207 7463.82124747896 6437.897510738327 5094.74750051014 6520.243002515761 5584.265551203468 5838.513978181185 6993.391235481904 5915.6744982770115 0.3729608352638132 1.0357635392486209 1.2617024905026228 1.0882778477100823 0.8612285043732589 1.1021977298471772 0.9439778258303311 0.9869565980822136 1.18217985751562 1.0 12.530326957004265 -4.762038921925832 7.19989044169454 1.0518121401831253 0.36011334715822657 0.7758079873943938 0.10943890359550715 0.049312095420406855 16.14847272674577 0.028047891560999388 0.1672027697600414 1.729661338209911e-05 4.762038921925832 -0.6916987930248988 HGS(ph)SDISSPR ddPTM_PC-9_Lapatinib_30min_R1 1 HGSSDISSPR 10 0 Q9BRD0 Q9BRD0 BUD13 BUD13 homolog 1 HGS(0.965)S(0.035)DISSPR 81.625 0.040045 0.0 6111.3 3861.0 7061.6 5314.8 6389.8 5676.0 3794.1 4707.1 5216.3 4250.1 True False 6024.15174132484 3852.060091719131 6481.0225065642835 5705.6681216530615 6013.964526830149 5433.250711402248 3990.539933326124 4925.809050113386 4628.785363925841 4984.7241220977285 1.2085225969917244 0.7727729754677102 1.3001767696297033 1.1446306720083712 1.206478910271023 1.0899802232416758 0.8005538191443139 0.9881808761044233 0.9285940907754595 1.0 12.283297946016733 -7.101505801301108 7.47060638444027 0.9290440745182438 1.1204801607847308 0.3133435513262248 0.13928543435274307 0.3549447012005568 23.071659561311225 0.053012683780649536 0.041064512734299306 7.91578880651301e-08 7.101505801301108 0.191436086266487 HGS(ph)VSADEAAR ddPTM_PC-9_AZD4547_30min_R2 2 HGSVSADEAAR 11 0 A0A1B0GU90;A0A1B0GW73;H3BNF1;A0A1B0GTV3;A0A0S2Z5D0;H3BUV4;A0A1B0GUD2;H3BUT1;A0A1B0GTU6;Q9NWW5;Q9NWW5-2 A0A1B0GU90 CLN6 Ceroid-lipofuscinosis neuronal protein 6 1 HGS(0.974)VS(0.026)ADEAAR;HGS(0.999)VS(0.001)ADEAAR 124.6 0.00050337 66483000.0 20469.0 25875.0 38575.0 26805.0 30421.8 14468.5 25282.7 28022.0 25978.0 18386.4 True False 26977.716218351063 34238.58773679678 38063.47029554275 20625.521383121693 26198.258188492055 13563.782407776438 27532.811320920235 23691.843781500353 27351.144044861878 17742.697732384608 1.5204968615967778 1.9297284016907574 2.1453034295944713 1.1624794433303822 1.4765656600616068 0.7644712552939081 1.5517826959688525 1.3353010990125336 1.5415437075805891 1.0 14.114937764004274 -5.771015529697451 24.999774584556523 1.2760229563969119 1.8716314686742244 0.5068182440552144 0.27250862177699214 155.90290710480247 407005.0458673317 0.07557289165738346 0.11373000296636537 1.6942772146372986e-06 5.771015529697451 0.5956085122773125 HGS(ph)VSADEAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HGSVSADEAAR 11 0 A0A1B0GU90;A0A1B0GW73;H3BNF1;A0A1B0GTV3;A0A0S2Z5D0;H3BUV4;A0A1B0GUD2;H3BUT1;A0A1B0GTU6;Q9NWW5;Q9NWW5-2 A0A1B0GU90 CLN6 Ceroid-lipofuscinosis neuronal protein 6 1 HGS(0.855)VS(0.145)ADEAAR;HGS(0.554)VS(0.446)ADEAAR;HGS(0.996)VS(0.004)ADEAAR;HGS(0.974)VS(0.026)ADEAAR 107.97 0.0022438000000000002 61486000.0 27239.300000000003 39062.2 38803.2 28796.4 51223.5 28010.200000000004 35108.600000000006 25795.200000000004 27152.6 23536.2 True False 31850.375489301598 42940.03706291371 39728.4154499555 27183.03106718842 41186.62288597147 26541.295802861016 31782.859243747713 25118.103332273593 27549.655407327555 27803.1267475433 1.145568114640772 1.5444319429543267 1.4289189777356939 0.9776969084813574 1.4813665836922727 0.9546155022008889 1.1431397458401351 0.903427285727604 0.9908833512677439 1.0 14.762959517516734 -6.795213407098966 0.8454801243081629 0.9587519013967092 1.3561685949366151 0.400932289585915 0.1763675261030695 0.5830965841268252 0.9039203052309693 0.11267968191634971 0.10249489417701672 1.6024577686661336e-07 6.795213407098966 0.39741669353990594 HGS(ph)VSADEAAR ddPTM_PC-9_Lapatinib_30min_R1 2 HGSVSADEAAR 11 0 A0A1B0GU90;A0A1B0GW73;H3BNF1;A0A1B0GTV3;A0A0S2Z5D0;H3BUV4;A0A1B0GUD2;H3BUT1;A0A1B0GTU6;Q9NWW5;Q9NWW5-2 A0A1B0GU90 CLN6 Ceroid-lipofuscinosis neuronal protein 6 1 HGS(0.993)VS(0.007)ADEAAR;HGS(0.999)VS(0.001)ADEAAR 126.34 0.00041543 50119000.0 48916.0 58047.0 28072.0 17439.8 21359.3 23498.1 23229.0 20668.6 35791.0 9894.300000000001 True False 48218.448869904234 57912.59573789707 25764.028521053682 18722.38106946734 20102.98796799951 22493.1410397465 24431.683959630074 21628.938610433925 31759.84068406146 11604.516571673972 4.155144987909534 4.990522042017566 2.2201724959351044 1.6133701868432597 1.7323417002195394 1.9383091833959805 2.105359909543027 1.8638379700563357 2.7368516808003527 1.0 13.502398802776819 -5.315144993711876 5.515812589027717 1.909244454849572 4.57348329524175 0.8462779365823002 0.4561638502866241 0.062111421691272546 4.267843165794348 0.11362024564965408 0.24806044098141175 4.840107486039628e-06 5.315144993711876 2.6642388403921777 HGS(ph)YEDAVHSGALND ddPTM_PC-9_AZD4547_30min_R2 2 HGSYEDAVHSGALND 15 0 P17987;F5H282;E7EQR6 P17987 TCP1 T-complex protein 1 subunit alpha 1 HGS(0.997)Y(0.003)EDAVHSGALND;HGS(0.992)Y(0.008)EDAVHSGALND 78.501 0.0067056 8228000.0 22556.0 24734.0 24500.3 28239.0 32838.0 29828.0 25526.0 31031.0 32303.0 25123.0 True False 29728.338806054355 32728.78180026785 24175.41001378837 21728.934838200836 28279.010525139933 27962.850444700933 27797.76454958566 26235.871971441655 34010.47063211844 24243.451416846063 1.2262420187167329 1.3500050482715338 0.9971934110416962 0.8962805858204677 1.1664597601597964 1.1534187094033306 1.1466092047549719 1.0821838656690241 1.4028724725426498 1.0 14.565307482135447 HGS(ph)YEDAVHSGALND ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HGSYEDAVHSGALND 15 0 P17987;F5H282;E7EQR6 P17987 TCP1 T-complex protein 1 subunit alpha 1 HGS(0.997)Y(0.002)EDAVHSGALND;HGS(1)YEDAVHSGALND 81.703 0.008549600000000001 7147400.0 31499.0 42003.0 32791.0 36982.0 33314.0 34023.0 38126.0 33163.0 30449.0 29391.0 True False 36831.15856639161 46172.78025184359 33572.86180055999 34910.018437261686 26786.36084654998 32238.77398593157 34514.42927166348 32292.50638910296 30894.259021151443 34719.35564097201 1.0608249458099817 1.3298858633584631 0.9669782512017864 1.0054915419013328 0.7715108864215102 0.9285533498751593 0.9940976332790377 0.9301009708542762 0.8898281218299281 1.0 15.083452552498876 -5.3939949553336515 5.896412933828193 0.9287852643919403 1.1935065071160742 0.5817245839476941 0.08832451722152133 0.142392451991752 6.164209595407828 0.02258823303517199 0.047810148248043485 4.036500816483087e-06 5.3939949553336515 0.2647212427241339 HGS(ph)YEDAVHSGALND ddPTM_PC-9_Lapatinib_30min_R1 2 HGSYEDAVHSGALND 15 0 P17987;F5H282;E7EQR6 P17987 TCP1 T-complex protein 1 subunit alpha 1 HGS(1)YEDAVHSGALND;HGS(0.999)Y(0.001)EDAVHSGALND 122.75 2.5653000000000003e-05 6576100.0 22884.0 28725.0 29537.0 30784.0 33027.0 30519.0 26553.0 29023.0 28997.0 28364.0 True False 22557.669963588378 28658.489027358748 27108.5818761172 33047.958052413596 31084.416793580283 29213.77351326378 27927.784415173155 30371.514533670597 25731.052508053155 33266.6796073457 0.6780860076762023 0.8614772909596482 0.8148869137553267 0.99342520631714 0.9344009429398074 0.8781692028805006 0.8395122310014478 0.9129710236234152 0.7734782314244375 1.0 15.021790255596736 -4.215750286748928 1.3657821631198033 0.894208548018592 0.11066767947757669 0.47145081843490333 0.06834048648382524 4.6581125341187075 2.639147564704103 0.019315869208313765 7.3805004583916345 6.084847709430007e-05 4.215750286748928 -0.7835408685410152 HGSGADS(ph)DYENTQSGDPLLGLEGK ddPTM_PC-9_Lapatinib_30min_R1 1 HGSGADSDYENTQSGDPLLGLEGK 24 0 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QL89 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 HGS(0.346)GADS(0.64)DY(0.013)ENT(0.001)QSGDPLLGLEGK 84.10700000000001 1.3554000000000001e-05 11080000.0 36432.0 53829.0 60639.0 52825.0 66227.0 75228.0 68942.0 79154.0 70429.0 63684.0 True False 35912.47299918945 53704.36225774389 55653.49549330912 56709.92671903421 62331.658067291675 72010.67380503312 72511.47942420325 82831.78380588385 62496.54436975122 74691.69454640403 0.48080945568690975 0.7190138419523839 0.745109557779989 0.7592534493082331 0.834519265439434 0.9641055038628791 0.9708104745053512 1.1089825222056329 0.8367268241708417 1.0 16.188660208870765 -4.401098758837445 0.38575721375927086 1.015096348230063 1.2766178656122766e-13 0.7990027087187842 0.07630105560263074 3.3974593063815473 0.32025168138560145 0.0640875987756109 1.6928725112859002 3.971012381309077e-05 4.401098758837445 -1.0150963482299353 down HGSGADSDYENT(ph)QSGDPLLGLEGK ddPTM_PC-9_Lapatinib_30min_R1 1 HGSGADSDYENTQSGDPLLGLEGK 24 0 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QL89 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 HGS(0.211)GADS(0.258)DY(0.192)ENT(0.316)QS(0.023)GDPLLGLEGK 56.903 0.0141 1534000.0 8307.4 10747.0 9856.2 11225.0 12195.0 13343.0 15184.0 13293.0 13569.0 13259.0 True False 8188.934952609425 10722.115981793713 9045.861282032247 12050.523945502293 11477.714076292481 12772.35099405218 15970.153224117414 13910.641308482347 12040.71633209549 15550.80048349303 0.5265925031513247 0.6894896499492162 0.5816974689910214 0.7749134173699781 0.7380786660131048 0.821330773782987 1.0269666337157062 0.894528955165254 0.7742827351477213 1.0 13.924701225104165 -6.25163103735493 0.8265396715296449 0.9199311238463908 0.5793540975531164 0.7131515517782776 0.0825713111142166 0.37570268944147145 0.5510752214453551 0.044460989494249016 0.07596384269916484 5.602333556416208e-07 6.25163103735493 -0.34057702629327435 HGTDLWIDNMSSAVPNHS(ph)PEKK ddPTM_PC-9_AZD4547_30min_R2 3 HGTDLWIDNMSSAVPNHSPEKK 22 1 Q8N6H7;H0YF45;E9PJT7;E9PK28;E9PN48;E9PIY6 Q8N6H7 ARFGAP2 ADP-ribosylation factor GTPase-activating protein 2 1 HGTDLWIDNMS(0.001)SAVPNHS(0.998)PEKK;HGTDLWIDNMS(0.002)S(0.002)AVPNHS(0.995)PEKK;HGTDLWIDNMSSAVPNHS(1)PEKK 92.39 7.101899999999999e-05 65388000.0 139947.0 133654.0 320388.0 486727.0 430987.0 394831.0 266120.0 393532.0 315547.0 397012.0 True False 184447.2349215678 176855.04175357823 316139.4457821997 374519.610007188 371151.8944271428 370142.1551539393 289804.16445724946 332720.6718657273 332226.17021803226 383112.7307210473 0.4814437634959926 0.4616266377280744 0.825186480196576 0.9775702553718681 0.968779851634287 0.966144232422931 0.7564461872927479 0.8684667597433311 0.8671760126393016 1.0 18.547409441318315 -5.321066098305313 3.8114104283248285 0.9067095844000507 0.46476348535816686 0.8631206325875208 0.06944649447709939 0.07696830186019567 2.2453155256549326 0.019907537060527607 0.047802750385518955 4.774566006784105e-06 5.321066098305313 -0.4419460990418838 HGTDLWIDNMSSAVPNHS(ph)PEKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HGTDLWIDNMSSAVPNHSPEKK 22 1 Q8N6H7;H0YF45;E9PJT7;E9PK28;E9PN48;E9PIY6 Q8N6H7 ARFGAP2 ADP-ribosylation factor GTPase-activating protein 2 1 HGTDLWIDNMS(0.001)S(0.001)AVPNHS(0.999)PEKK;HGTDLWIDNMSS(0.001)AVPNHS(0.999)PEKK;HGTDLWIDNMS(0.007)S(0.007)AVPNHS(0.986)PEKK 95.666 5.5651000000000006e-05 31467000.0 99056.0 120650.0 170844.0 250866.0 287855.0 269598.0 262883.0 241355.0 262524.0 178755.0 True False 115824.22435482053 132627.33465192775 174917.56888947828 236810.7913385457 231451.87913440686 255459.80627984516 237980.8191318974 235019.6869867609 266362.91685338604 211161.8664761982 0.5485091900713808 0.6280837391010525 0.8283577513707698 1.1214657044397673 1.0960874849081508 1.209781910639818 1.1270066092104856 1.112983565208503 1.261415810053043 1.0 17.687989797708276 -5.517621280726401 1.7580394102678054 1.146901634524442 0.5550106048894592 0.9154159407336491 0.06735894646901906 0.0914548965375928 0.5445929307088694 0.01906869957001449 0.05469103752620014 3.036537992383524e-06 5.517621280726401 -0.5918910296349829 HGTDLWIDNMSSAVPNHS(ph)PEKK ddPTM_PC-9_Lapatinib_30min_R1 2 HGTDLWIDNMSSAVPNHSPEKK 22 1 Q8N6H7;H0YF45;E9PJT7;E9PK28;E9PN48;E9PIY6 Q8N6H7 ARFGAP2 ADP-ribosylation factor GTPase-activating protein 2 1 HGTDLWIDNMS(0.014)S(0.072)AVPNHS(0.914)PEKK;HGTDLWIDNMS(0.01)S(0.01)AVPNHS(0.98)PEKK 104.45 1.5261e-05 21280000.0 126543.0 79574.0 130519.0 107955.0 155670.0 151085.0 94996.0 121012.0 172041.0 79314.0 True False 124738.47361485606 79389.75129201195 119788.23163790983 115894.37082732275 146513.79665899547 144623.44674633673 99914.4280610022 126634.65929602562 152663.93090795493 93023.31922073818 1.3409376773458268 0.8534392446653652 1.2877226123662637 1.24586363718449 1.5750222405129184 1.5547009928032653 1.0740793695386408 1.36132165952421 1.6411361386244832 1.0 16.50530479799577 -5.626600932233342 2.647838476733965 1.3756769920742145 1.096048617391049 0.14705724589004932 0.22724286718718584 0.4372980079624766 6.159950514504107 0.0637971340298504 0.1289868196172649 2.3626482439460687e-06 5.626600932233342 -0.27962837468316537 HGVESTLER ddPTM_PC-9_AZD4547_30min_R2 2 HGVESTLER 9 0 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 0 ; 126.31 0.0011737 6885000.0 23923.6 21878.7 39339.0 58102.0 51048.0 39887.0 30438.0 47140.0 33834.0 50634.0 False True 31530.807158207226 28950.561913702615 38817.33915635401 44707.48156695158 43960.86635262025 37392.85958454427 33146.9230337808 39855.59616943568 35622.39616652001 48861.319071790116 0.6453122379254679 0.5925047146428166 0.7944390346752846 0.9149872008421333 0.8997069090179531 0.7652855120346697 0.6783878058035899 0.8156880928833979 0.7290510539468112 1.0 15.576405191018777 -14.52287874523556 0.029383211810841633 2.085760992153088 3.747778269572252e-08 0.34476892425399164 0.09872168824405653 2219.18015372411 4.892745008482863 268.7761402800127 110.63543312184949 3.000000000309307e-15 14.52287874523556 -2.0857609546753055 HGVESTLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HGVESTLER 9 0 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 0 ; 125.97 0.001183 3729600.0 22247.5 26561.0 41499.0 35410.0 47661.0 43578.0 36806.0 42553.0 44360.0 30018.0 False True 26013.562341845696 29197.80054446627 42488.49354583391 33426.09250076892 38322.16918735122 41292.69296531542 33319.4692276359 41436.02883863039 45008.68107912507 35460.02577764276 0.7336024656317938 0.8234004320119596 1.1982081968091105 0.9426415172502154 1.0807146454899932 1.164485700722477 0.9396346589416056 1.16852788259267 1.2692794235784977 1.0 15.113905964552657 -5.1319212474493145 4.816616869201909 1.091771615218541 0.7544030794980032 0.598782371536138 0.10457859115402332 0.14355245105220238 4.89180725517955 0.02672686896215714 0.07730362351993351 7.3803804971895e-06 5.1319212474493145 -0.3373685357205378 HGVESTLER ddPTM_PC-9_Lapatinib_30min_R1 2 HGVESTLER 9 0 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 0 ; 107.21 0.0021133000000000002 3158600.0 28629.5 20421.3 34227.0 27319.1 34081.0 34284.9 27056.0 27680.4 35836.0 25683.7 False True 28221.23807999271 20374.015734530934 31412.988180040757 29328.23774784604 32076.422585824028 32818.61474900546 28456.82729397528 28966.532436268335 31799.77231019047 30123.09332362096 0.9368638797086315 0.6763586832084968 1.0428207967409617 0.9736130825863214 1.0648449095588524 1.0894835532468643 0.9446847635551731 0.9616055072788388 1.055660916644797 1.0 14.878582306714096 -5.280279984969068 24.87235472083556 1.0154418813774697 0.806611272111759 0.565865218425192 0.07356257490532901 447.70365756822633 591033.7762363539 0.018438906385533742 0.038487427002630255 5.244692315775562e-06 5.280279984969068 -0.20883060926571073 HGVIVAADSR ddPTM_PC-9_Lapatinib_30min_R1 2 HGVIVAADSR 10 0 P28074;H0YJM8;P28074-2 P28074 PSMB5 Proteasome subunit beta type-5 0 ; 95.48299999999999 0.0049513000000000005 2828300.0 29987.0 31865.0 39443.0 44380.0 35532.0 39711.0 31729.0 34404.0 40287.0 34699.0 False True 29559.379881057695 31791.21855027977 36200.14879438302 47643.853247340005 33442.077618599775 38012.65310086232 33371.772368810656 36002.5354379769 35749.45381908258 40696.6759164888 0.7263340116945847 0.7811748216369468 0.8895111941984444 1.1707062597718567 0.8217397825617073 0.9340481069968909 0.8200122397537053 0.8846554325924686 0.878436703096879 1.0 15.312623340265924 -5.238427843174629 3.752011481978999 0.9234693573824071 0.7441470236566599 0.3426345495970863 0.09633685721293916 0.2615760660723903 8.147374980037684 0.02595767969098937 0.0725939289942964 5.775268192246696e-06 5.238427843174629 -0.17932233372574724 HGVVPLATYMR ddPTM_PC-9_Lapatinib_30min_R1 1 HGVVPLATYMR 11 0 P46778;M0R181;G3V1B3 P46778 RPL21 60S ribosomal protein L21 0 90.82700000000001 0.0071551 3011500.0 48438.0 37098.0 37531.0 37592.0 38906.0 38912.0 35972.0 35845.0 37290.0 32692.0 False True 47747.26523755868 37012.10186029431 34445.34605384955 40356.64108323585 36617.62557213902 37247.82446830235 37834.45414765222 37510.48955860602 33090.00751889168 38342.76864064819 1.2452743223904945 0.9652954956689485 0.8983531256356152 1.052522874950994 0.9550073422011498 0.9714432678921089 0.9867428850076024 0.978293714524312 0.863005168693324 1.0 15.226666893913887 -4.761483936362561 10.236476446551547 0.9641348381915164 1.246288967359953 0.7447817754623767 0.04949903204382886 0.03426454991891991 85.73532167153903 0.01189539703020749 0.06709496112214382 1.7318730879003548e-05 4.761483936362561 0.28215412916843674 HGVYNPNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HGVYNPNK 8 0 P40926;G3XAL0 P40926 MDH2 Malate dehydrogenase, mitochondrial;Malate dehydrogenase 0 90.777 0.0077391000000000005 6264900.0 111440.0 129150.0 127540.0 145880.0 148220.0 148730.0 131760.0 135580.0 123050.0 117040.0 False True 130304.59095967148 141971.15847738457 130581.03729814346 137706.8165493414 119177.35500617263 140930.3369757988 119278.73894020809 132021.16865888456 124849.37346227086 138258.42551186957 0.9424712488750622 1.0268535747587857 0.9444707388696033 0.9960103049019546 0.8619898177268132 1.0193254874271647 0.8627231107153606 0.9548869674315108 0.9030145757847681 1.0 17.077007875864645 HGVYNPNK ddPTM_PC-9_Lapatinib_30min_R1 2 HGVYNPNK 8 0 P40926;G3XAL0 P40926 MDH2 Malate dehydrogenase, mitochondrial;Malate dehydrogenase 0 ; 79.45100000000001 0.017368 12908000.0 257315.0 214094.0 187488.0 170204.0 160760.0 149618.0 135820.0 134995.0 192857.0 138392.0 False True 253645.64091420756 213598.27849689565 172073.4603646091 182721.3699438995 151304.41286632066 143219.18691659276 142852.09502763615 141267.36052347667 171135.4137857572 162312.87280425156 1.562695777186464 1.3159663482421016 1.0601344021070267 1.1257355426409124 0.9321775300520555 0.8823649316423247 0.8801033002472638 0.8703398447875687 1.0543551526695334 1.0 17.308417896962226 -4.519477747160493 0.7433885041704529 0.9243804152285501 2.2035486216981717 0.8916069367005369 0.06919320662143733 1.1576195050679388 0.37247252110832 0.02801316921362955 1.3518520469574127 3.0235854922102283e-05 4.519477747160493 1.2791682064696217 HGYIGEFEIIDDHR ddPTM_PC-9_AZD4547_30min_R2 3 HGYIGEFEIIDDHR 14 0 I3L3P7;I3L246;H3BN98;P62244 I3L3P7 RPS15A 40S ribosomal protein S15a 0 ;; 129.54 9.3662e-06 17114700.0 81474.4 84900.4 98151.0 123790.0 117562.0 110015.0 83586.0 109755.0 84855.0 112045.0 False True 107381.56442720331 112342.79398218881 96849.45360927584 95252.12803643486 101240.54556783287 103135.74465850115 91024.99207246226 92794.8866689949 89340.2620650841 108122.33865384349 0.9931487402523563 1.0390340736326211 0.8957395374081013 0.880966220508669 0.9363517921301827 0.9538800764261394 0.841870359129774 0.8582397294057815 0.8262886576205987 1.0 16.722305096821735 -5.26872301187739 23.881510933548256 0.8946898954021293 1.0160914110197863 0.4515926061350687 0.05135059051836922 233.8314449680644 766689.1448570532 0.013585753791082001 0.029291909726992797 5.386131944134782e-06 5.26872301187739 0.121401515617657 HGYIGEFEIIDDHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HGYIGEFEIIDDHR 14 0 I3L3P7;I3L246;H3BN98;P62244 I3L3P7 RPS15A 40S ribosomal protein S15a 0 ;;; 107.65 0.00032004 20114000.0 105226.0 112124.0 130457.0 132621.0 132860.0 109639.0 133828.0 150775.0 117026.0 96374.0 False True 123038.68349176589 123254.92971829881 133567.58964092765 125190.67533308332 106827.03674349016 103889.33783157138 121150.84300918458 146817.31600931744 118737.28385855924 113845.84330383598 1.0807481408293118 1.0826476061084769 1.1732320281949824 1.0996508234294495 0.93834815258372 0.9125439701325563 1.0641657129795485 1.289615077271517 1.0429654734224139 1.0 16.79672209173991 -10.937136297178895 14.628150981510068 1.0000043679080153 1.0768221861839966 0.04815056695481945 0.10129907256844779 7.303193261536767e-10 0.0 0.10720777935690591 0.026001705775084455 1.1557494696496602e-11 10.937136297178895 0.07681781827598133 HGYIGEFEIIDDHR ddPTM_PC-9_Lapatinib_30min_R1 1 HGYIGEFEIIDDHR 14 0 I3L3P7;I3L246;H3BN98;P62244 I3L3P7 RPS15A 40S ribosomal protein S15a 0 107.53 0.00032471 1236900.0 6805.6 6211.5 5806.4 7711.5 8578.0 7512.2 5592.6 7622.5 8030.8 7007.5 False True 6708.550896005808 6197.117653383426 5329.020205352164 8278.629434809885 8073.458904996874 7190.920717793511 5882.1574631980375 7976.669177304352 7126.28673592693 8218.737038093179 0.8162508259982305 0.7540231089838121 0.6483989183073492 1.0072872993063424 0.9823235452815983 0.8749423037218709 0.7157008961273144 0.9705468298028198 0.8670780805976843 1.0 13.00470099865785 -1.522878745280339 0.13782318520453066 0.9969739328595887 0.17361031067899427 0.21666551489702712 0.10743911219978125 132.6796686486489 1.2268808121262849 0.5220384590937626 21.445400216719335 0.029999999999999905 1.522878745280339 -0.8233636221805944 HHEDNLLR ddPTM_PC-9_AZD4547_30min_R2 2 HHEDNLLR 8 0 O75643 O75643 SNRNP200 U5 small nuclear ribonucleoprotein 200 kDa helicase 0 ; 158.07 3.0966e-05 42716000.0 35917.0 27314.0 38786.0 60370.0 42893.1 38842.0 34207.0 55027.0 28041.0 44390.0 False True 47337.858879989995 36142.716345618035 38271.67229767778 46452.629207202306 36938.13345379986 36413.20359974098 37251.356732260334 46523.841544665614 29523.1900131639 42835.919611264435 1.1050972947372348 0.8437478796676444 0.8934481305640884 1.0844317019165102 0.8623168076934749 0.850062375926336 0.8696289719075964 1.0860941463815657 0.6892157395262334 1.0 15.38653344047422 HHEDNLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HHEDNLLR 8 0 O75643 O75643 SNRNP200 U5 small nuclear ribonucleoprotein 200 kDa helicase 0 ;; 143.89 3.3334999999999997e-09 0.0 26783.6 21693.699999999997 28408.2 31663.6 37983.5 31154.5 30697.0 28560.5 24166.0 20190.4 False True 31317.534479786867 23847.307167331357 29085.559226698468 29889.59114677627 30540.90584183622 29520.703175637213 27789.157932965783 27810.817137351136 24519.382032419664 23850.759692881533 1.313062346149664 0.9998552446297463 1.2194814589230591 1.2531924153215581 1.2805003377293436 1.2377259070891533 1.1651267419066613 1.1660348557220808 1.0280335866927413 1.0 14.541747599142822 -8.214674419515621 1.8200748195641945 0.9948930700132208 1.2089951296812953 0.48371023256221835 0.08018639642487538 0.314640347108576 1.8955568623379204 0.0757157883617589 0.022728509688610624 6.09994024219757e-09 8.214674419515621 0.2141020596680745 HHEDNLLR ddPTM_PC-9_Lapatinib_30min_R1 1 HHEDNLLR 8 0 O75643 O75643 SNRNP200 U5 small nuclear ribonucleoprotein 200 kDa helicase 0 68.22399999999999 0.03708 14794000.0 8238.5 6299.2 6900.2 5588.9 7279.0 5517.4 5941.4 6558.5 8123.9 5385.6 False True 8121.01747924413 6284.614589421694 6332.892191542269 5999.926350023856 6850.863531064616 5281.433663687588 6249.016620506532 6863.231852981376 7208.900833540463 6316.493784139079 1.2856843933949984 0.99495302365413 1.0025961249964919 0.9498824118357981 1.0845991091240137 0.8361337546075702 0.9893173070474659 1.0865572084017836 1.1412820276404367 1.0 12.624908241180579 -4.760003187052746 24.819848224944792 1.0064077590592952 1.2856847681075354 0.5196210953650064 0.07962168722382384 27.955736576883403 482935.5540994893 0.020462621079016637 0.12468825986654697 1.7377880760140493e-05 4.760003187052746 0.27927700904824015 HHEEEIVHHK ddPTM_PC-9_AZD4547_30min_R2 2 HHEEEIVHHK 10 0 Q9UII2 Q9UII2 ATPIF1 ATPase inhibitor, mitochondrial 0 ; 85.86200000000001 0.0048937 2013140.0 9021.5 7589.4 10107.3 11525.1 9159.400000000001 11985.1 9196.2 12989.0 11184.0 10492.0 False True 11890.149341142907 10042.525131194021 9973.270598007504 8868.166256019995 7887.775412752508 11235.66980235971 10014.643984600008 10981.848507526522 11775.163407411468 10124.678273516256 1.1743730536351662 0.9918858515695133 0.9850456803249938 0.8758961041969109 0.7790643020613354 1.1097310451581994 0.9891320705761021 1.084661478701246 1.1630160573311734 1.0 13.30558844452675 HHFETLTES(ph)PCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HHFETLTESPCR 12 0 O43379;O43379-4 O43379 WDR62 WD repeat-containing protein 62 1 HHFET(0.002)LT(0.177)ES(0.821)PCR 67.29899999999999 0.021091 7345900.0 39167.0 56611.0 34047.0 37256.0 50523.0 38442.0 39207.0 35383.0 44146.0 29738.0 True False 45797.199516488145 62230.965950934886 34858.80960396652 35168.667105581706 40623.380832390125 36426.03384672668 35493.02912590122 34454.23374138742 44791.551733973254 35129.263994121524 1.3036766020532562 1.7714850490846754 0.9923011654841313 1.0011216606037285 1.1563971519354341 1.0369142334670647 1.0103550456349035 0.9807843895378205 1.2750495353807756 1.0 15.100385730002296 -5.27432234813465 24.989969683243807 1.0551550570108548 1.5375808306514323 0.6657607519492499 0.1363117927717719 352.55921361038475 683883.2365753608 0.03321880859703852 0.06984578048516497 5.317134569559541e-06 5.27432234813465 0.4824257736405775 HHFETLTES(ph)PCR ddPTM_PC-9_Lapatinib_30min_R1 2 HHFETLTESPCR 12 0 O43379;O43379-4 O43379 WDR62 WD repeat-containing protein 62 1 HHFETLTES(1)PCR;HHFET(0.024)LT(0.371)ES(0.605)PCR 172.09 0.00064367 32482000.0 107247.0 129119.0 139561.0 114074.0 164775.0 141149.0 118530.0 140522.0 147858.0 120133.0 True False 105717.63811330886 128820.03288854785 128086.83330103893 122463.38249970876 155083.25846011424 135112.38630438954 124666.90342825586 147051.16512078192 131204.67502623462 140897.82898283977 0.750314173585914 0.9142797573143381 0.9090759895004407 0.8691644391101571 1.1006788364283608 0.9589387379478015 0.8848035795032675 1.0436723275465911 0.9312043767701651 1.0 17.104289856561145 -3.7357371431319164 0.7211344588525783 0.9758275273738366 7.311128805295511e-15 0.497879028446251 0.06575958573506492 9.772739010018137 1.240539155684171 0.025754958334120736 10.986891130106018 0.0001837650245198237 3.7357371431319164 -0.9758275273738293 HHNS(ph)TAELQK ddPTM_PC-9_AZD4547_30min_R2 2 HHNSTAELQK 10 0 A0A0A0MS99;I3L4X2;P33527-8;P33527-6;P33527-7;P33527-5;P33527-4;P33527-2;P33527-3;P33527;P33527-9 A0A0A0MS99 ABCC1 Multidrug resistance-associated protein 1 1 HHNS(0.994)T(0.006)AELQK;HHNS(0.832)T(0.168)AELQK 148.48 8.6033e-05 32052000.0 127310.0 296591.0 276713.0 350690.0 305977.0 237753.0 355090.0 358880.0 299209.0 311355.0 True False 167791.93178749667 392458.2405968802 273043.60481893766 269843.83860648924 263497.375097471 222886.2673252978 386692.3220995205 303423.34224198275 315024.57689272024 300454.5562190861 0.5584602673328933 1.3062149748553211 0.908768394977639 0.8981186439713164 0.8769957707192612 0.7418302126288048 1.2870243239631598 1.009880981870456 1.048493259203598 1.0 18.196787274108026 -7.253997193996593 24.99541577020985 1.0871730581016832 0.9027846705193812 0.21229918812877646 0.1905135663774656 1011.8861919937377 3398541.479747637 0.07184045766644573 0.05454159522259675 5.571893489550151e-08 7.253997193996593 -0.18438838758230203 HHNS(ph)TAELQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HHNSTAELQK 10 0 A0A0A0MS99;I3L4X2;P33527-8;P33527-6;P33527-7;P33527-5;P33527-4;P33527-2;P33527-3;P33527;P33527-9 A0A0A0MS99 ABCC1 Multidrug resistance-associated protein 1 1 HHNS(0.97)T(0.03)AELQK;HHNS(0.99)T(0.01)AELQK 132.06 9.0171e-05 19045300.0 99415.0 94518.0 134995.0 115732.0 351740.0 137593.0 134791.0 150293.0 130102.0 125778.0 True False 116243.99596424699 103901.12239229953 138213.7927713882 109247.91124820658 282819.07198671706 130377.38086136674 122022.62067766872 146347.96799859666 132004.49562119733 148580.55574189994 0.7823634484594003 0.6992915181498359 0.9302279970703575 0.7352773093538679 1.903472971779723 0.8774861569897878 0.8212556486168678 0.984973890209554 0.8884372181949772 1.0 17.18088580181937 HHNS(ph)TAELQK ddPTM_PC-9_Lapatinib_30min_R1 2 HHNSTAELQK 10 0 A0A0A0MS99;I3L4X2;P33527-8;P33527-6;P33527-7;P33527-5;P33527-4;P33527-2;P33527-3;P33527;P33527-9 A0A0A0MS99 ABCC1 Multidrug resistance-associated protein 1 1 HHNS(0.976)T(0.024)AELQK;HHNS(0.996)T(0.004)AELQK 152.88 8.1352e-05 30990000.0 405772.0 800030.0 200175.0 136063.0 192625.0 137615.0 96340.0 97093.0 386494.0 62069.0 True False 399985.61687052826 798177.5796886957 183717.3841978454 146069.5269128625 181295.1762153208 131729.52724623325 101328.01380475974 101604.29523542275 342962.9757577506 72797.54394825635 5.494493291625791 10.96434764689357 2.523675583456903 2.0065172393272914 2.4904023732474174 1.809532576261983 1.391915280504278 1.3957104831399518 4.711188828039648 1.0 16.15160215698657 -5.32351259107717 8.362457453500223 2.1354843231118754 8.217914914351091 0.7071298605622967 1.5609608713095073 0.14908631752739862 18.828302186910097 0.37903421859853414 0.7938249658751942 4.747745260663752e-06 5.32351259107717 6.082430591239216 HHPVFSS(ph)SDPLEK ddPTM_PC-9_AZD4547_30min_R2 1 HHPVFSSSDPLEK 13 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 HHPVFS(0.224)S(0.735)S(0.041)DPLEK 77.372 0.024849 0.0 42430.0 37542.0 51435.0 80417.0 56407.0 53742.0 59491.0 69049.0 68857.0 49949.0 True False 55921.85740117426 49676.7173261768 50752.938292968036 61878.10308026481 48575.861705693686 50381.50424430464 64785.5837506621 58379.06363817069 72496.64044564836 48200.30071329238 1.1601972720836673 1.030630858958049 1.052958955481614 1.283770062936567 1.0077916732228547 1.045252902963959 1.344090862337627 1.2111763365424664 1.5040702936041161 1.0 15.556754526756187 -7.259441828087003 24.98072475231073 1.2824324036022627 1.096225303656124 0.25578919931800814 0.13915077145879678 221.8765726005363 2774734.206516127 0.05238686190584507 0.03851094559077835 5.502476189211523e-08 7.259441828087003 -0.1862070999461387 HHS(ph)VEIK ddPTM_PC-9_AZD4547_30min_R2 1 HHSVEIK 7 0 Q14151 Q14151 SAFB2 Scaffold attachment factor B2 1 HHS(1)VEIK 71.61399999999999 0.023215 6977500.0 26524.0 32948.0 33266.0 57083.0 31157.0 55553.0 37365.0 48932.0 33730.0 43686.0 True False 34958.080266527126 43597.79666674318 32824.87110438173 43923.39627355854 26831.388358967804 52079.26212801637 40690.41261440371 41370.6837454991 35512.89893884023 42156.56643698351 0.8292440115772516 1.0341875620234409 0.77864195020363 1.0419111418672136 0.6364699648648072 1.2353772266027765 0.9652212230146533 0.9813580004752246 0.8424049190990361 1.0 15.36346974685521 -6.763725824086346 24.99999327487415 1.0012288975429078 0.8786725054592089 0.19205789131931383 0.14271884355452946 118.71586622527606 1298025.584846261 0.04712682796721936 0.04356717012403113 1.7229559568448376e-07 6.763725824086346 -0.12255639208369884 HHS(ph)VEIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HHSVEIK 7 0 Q14151 Q14151 SAFB2 Scaffold attachment factor B2 1 HHS(1)VEIK;HHS(1)VEIK 65.157 0.040371 0.0 59612.0 66919.0 72200.0 85869.0 112591.0 94067.0 90718.0 87440.0 81630.0 60356.0 True False 69703.13420933174 73562.27606773605 73921.5218200246 81058.03832105407 90529.6017912564 89133.96092451068 82124.53429855665 85144.79265033806 82823.68432121216 71298.06502216689 0.9776300968008138 1.0317569774841042 1.0367956240753808 1.1368897360097048 1.2697343436054027 1.2501596066709317 1.151848009802563 1.194209024099969 1.1616540265919124 1.0 16.12157530305165 -5.798562108371922 3.083373385575095 1.1852599211742563 1.0113514366745666 0.4925112999310137 0.07025950060743763 0.18722725666197015 3.6376603151451543 0.019830107164788995 0.03356255917834474 1.5901492606152208e-06 5.798562108371922 -0.17390848449968965 HHS(ph)VEIK ddPTM_PC-9_Lapatinib_30min_R1 1 HHSVEIK 7 0 Q14151 Q14151 SAFB2 Scaffold attachment factor B2 1 HHS(1)VEIK 73.985 0.026501999999999998 0.0 15407.0 36725.0 29634.0 23898.0 33899.0 34078.0 43861.0 26087.0 38146.0 19526.0 True False 15187.293354702239 36639.96551887726 27197.60691054804 25655.538641390973 31905.127467998245 32620.563379697964 46131.907966478764 27299.097255275617 33849.59578481206 22901.043083240453 0.6631703761046882 1.5999256184837838 1.1876143288185819 1.120278170218645 1.3931735489964299 1.4244138688848849 2.0144020426842144 1.1920460197401999 1.478080961717592 1.0 14.483125690393358 -6.413304836075657 3.645181478155221 1.4668617990381607 1.1791339971803028 0.13640443612891806 0.32296304870984055 0.4874775265449073 11.761410210907766 0.10229386400890393 0.1157343699859247 3.8609587697663594e-07 6.413304836075657 -0.28772780185785796 HHTAAFEER ddPTM_PC-9_AZD4547_30min_R2 3 HHTAAFEER 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ;; 125.71 0.0011899 11330500.0 7315.709999999999 8875.4 16645.1 19146.7 18180.8 12794.869999999999 11508.099999999999 15128.619999999999 13269.0 16072.64 False True 9641.953603779035 11744.199482093367 16424.37509828487 14732.724128566182 15656.70974345162 11994.80475624886 12532.298605856262 12790.839400102841 13970.372250799617 15509.941765730868 0.6216627856774343 0.7572046149162283 1.0589578830382482 0.9498890679988274 1.0094628322876773 0.7733623334905947 0.808017128313551 0.8246864877574287 0.9007366024846772 1.0 13.920905649131125 -5.015717540745117 5.6567006790399965 0.9057429802810495 0.6487283403842046 0.5287463368316323 0.08924455899026648 0.12419706468548848 14.427101068989225 0.02461542407048006 0.08041290809203036 9.644560888752867e-06 5.015717540745117 -0.2570146398968449 HHTAAFEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HHTAAFEER 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 79.986 0.016238 2862200.0 643.46 1107.9 0.0 578.93 564.87 403.58 807.76 1140.9 1116.0 451.96 False True 752.3850690856962 1217.8849901439785 0.0 546.4944290163843 454.1877784532238 382.41555433801443 731.2431251240337 1110.9525838834716 1132.3193887354269 533.8967702866086 1.4092332281422078 2.2811244755988853 0.0 1.0235956825942456 0.850703363890748 0.7162724624326245 1.3696339176794137 2.080837805568829 2.1208582852590974 1.0 9.06041701147693 -7.551004731756119 5.701327000908835 1.816233898068412 1.0440999621200626 0.1996022410357533 0.6107071800626185 0.26702168025195516 25.42994312093324 0.2964851005176276 0.17236383943302347 2.8118701941439755e-08 7.551004731756119 -0.7721339359483494 HHTAAFEER ddPTM_PC-9_Lapatinib_30min_R1 1 HHTAAFEER 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 114.86 0.0016902000000000002 2192500.0 577.41 851.52 675.16 571.36 737.11 893.49 821.41 886.92 2281.8 0.0 False True 569.1760275159744 849.5483577572323 619.650950992968 613.3797204010862 693.7546390140182 855.2775155269188 863.9385906100022 928.1295410606457 2024.7996555807717 0.0 0.0 HHVLHDQNVDKR ddPTM_PC-9_AZD4547_30min_R2 1 HHVLHDQNVDKR 12 1 E9PFG7;A0A0D9SFS3;E9PDF2;E9PCR7;Q02218-2;Q02218 E9PFG7 OGDH 2-oxoglutarate dehydrogenase, mitochondrial 0 42.802 0.031972 4263600.0 10198.0 14478.0 17920.0 19524.0 14271.0 20590.0 15300.0 16510.0 14652.0 20055.0 False True 13440.75186842269 19157.730367278964 17682.369091280012 15023.043442793061 12289.71798539108 19302.504045071484 16661.670359972606 13958.75886205734 15426.474807349154 19352.880554266914 0.6945091109684589 0.9899162201492054 0.9136815081195451 0.7762691140818718 0.6350330097336052 0.9973969503374874 0.8609400710789303 0.7212755136330193 0.7971151769418601 1.0 14.240260697963636 -11.880064036990817 2.144133677482799 2.020385148873878 0.8250859532433549 0.17770145482933153 0.11537212901493457 5507666.558692392 663219.2111526862 27219119.623864904 0.029568965049617355 1.318062375112246e-12 11.880064036990817 -1.1952991956305232 HHVLHDQNVDKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HHVLHDQNVDKR 12 1 E9PFG7;A0A0D9SFS3;E9PDF2;E9PCR7;Q02218-2;Q02218 E9PFG7 OGDH 2-oxoglutarate dehydrogenase, mitochondrial 0 50.452 0.022854 1498100.0 5540.1 5229.8 4846.8 5278.1 4587.6 3750.3 4343.8 4410.5 2611.1 3674.2 False True 6477.929508037277 5748.979981455885 4962.366093591359 4982.385168831077 3688.6927123621545 3553.6276659741684 3932.32381761139 4294.72904831103 2649.282397784118 4340.303375048804 1.492506156430698 1.3245571760041408 1.1433224050923767 1.1479347728256561 0.8498697887266181 0.8187509855654296 0.9060020643297022 0.9894997370460857 0.6103910646002547 1.0 12.08358017119863 -5.413268957125005 0.7968845887765263 0.8487141638995154 1.5833540138724267 0.7865889937565338 0.11301212549547915 0.5453212158913113 0.47804998738016796 0.04763529091000491 0.30425816215236023 3.86127775349114e-06 5.413268957125005 0.7346398499729113 HHYEQQQEDLAR ddPTM_PC-9_AZD4547_30min_R2 4 HHYEQQQEDLAR 12 0 Q12873;Q12873-3;Q12873-2;A0A5F9ZHX5;K7EMY3;Q8TDI0;Q14839-2;A0A2R8Y8C1;A0A0C4DGG9;A0A2R8Y521;A0A2R8Y212;F5GWX5;A0A2U3TZM0;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8YER1;Q14839;A0A2R8YDJ9;A0A2R8YD40;A0A2R8YE38;A0A2R8YDW2;A0A2R8YFD8;A0A2R8Y5M9;A0A2R8Y5Z7;A0A2R8Y4X2;A0A2R8Y7I0 Q12873;Q14839-2 CHD3;CHD5;CHD4 Chromodomain-helicase-DNA-binding protein 3;Chromodomain-helicase-DNA-binding protein 5;Chromodomain-helicase-DNA-binding protein 4 0 ;;; 174.23 0.00011286 12139900.0 38608.0 31854.2 48123.0 66935.8 54829.600000000006 47199.200000000004 40933.0 58496.9 42333.9 50891.5 False True 50884.5409037128 42150.44720716797 47484.857576990355 51504.785457801125 47217.45646778775 44247.82656260996 44575.95770227181 49457.548230035274 44571.58352763026 49109.804075167034 1.0361381370169869 0.8582898669816085 0.9669119735096163 1.048767887140587 0.9614670096324784 0.9009978230596202 0.9076794041785269 1.0070809517858386 0.9075903349035843 1.0 15.58372344642499 -6.53282172513674 24.47236710801563 0.9415150396293235 0.9728600240633203 0.06150588280623959 0.05880865883293064 542.9195342521864 1336258.1739059864 0.019612382849854358 0.01963688123721851 2.93209660350429e-07 6.53282172513674 0.0313449844339968 HHYEQQQEDLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HHYEQQQEDLAR 12 0 Q12873;Q12873-3;Q12873-2;A0A5F9ZHX5;K7EMY3;Q8TDI0;Q14839-2;A0A2R8Y8C1;A0A0C4DGG9;A0A2R8Y521;A0A2R8Y212;F5GWX5;A0A2U3TZM0;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8YER1;Q14839;A0A2R8YDJ9;A0A2R8YD40;A0A2R8YE38;A0A2R8YDW2;A0A2R8YFD8;A0A2R8Y5M9;A0A2R8Y5Z7;A0A2R8Y4X2;A0A2R8Y7I0 Q12873;Q14839-2 CHD3;CHD5;CHD4 Chromodomain-helicase-DNA-binding protein 3;Chromodomain-helicase-DNA-binding protein 5;Chromodomain-helicase-DNA-binding protein 4 0 ;; 162.68 0.00040924 5899500.0 45081.799999999996 43955.9 51837.9 51100.3 62058.3 57302.6 50401.8 49126.1 42961.100000000006 41079.200000000004 False True 52713.258333863065 48319.5512575771 53073.91213233051 48237.31586040789 49898.42160423405 54297.55078053796 45627.376626567915 47836.5919284055 43589.32481308386 48526.533777231714 1.0862770165256628 0.9957346527035127 1.0937091113075212 0.9940400046260975 1.028270880283768 1.1189249788538156 0.9402562490044557 0.9857821732746563 0.8982575391266797 1.0 15.566486192443795 -7.285493839761248 24.99496559619806 0.9548891595997105 1.0483011214398064 0.5153029097725661 0.04583789835764649 654.6187292295616 680210.3445462957 0.018257705159100864 0.012315307650794494 5.182104424976022e-08 7.285493839761248 0.09341196184009581 HHYEQQQEDLAR ddPTM_PC-9_Lapatinib_30min_R1 4 HHYEQQQEDLAR 12 0 Q12873;Q12873-3;Q12873-2;A0A5F9ZHX5;K7EMY3;Q8TDI0;Q14839-2;A0A2R8Y8C1;A0A0C4DGG9;A0A2R8Y521;A0A2R8Y212;F5GWX5;A0A2U3TZM0;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8YER1;Q14839;A0A2R8YDJ9;A0A2R8YD40;A0A2R8YE38;A0A2R8YDW2;A0A2R8YFD8;A0A2R8Y5M9;A0A2R8Y5Z7;A0A2R8Y4X2;A0A2R8Y7I0 Q12873;Q14839-2 CHD3;CHD5;CHD4 Chromodomain-helicase-DNA-binding protein 3;Chromodomain-helicase-DNA-binding protein 5;Chromodomain-helicase-DNA-binding protein 4 0 ;;; 168.98 0.00017396 9338500.0 43024.8 36083.0 46260.1 34316.700000000004 42328.6 36548.2 34033.8 34658.2 41729.8 29229.2 False True 42411.25846221799 35999.45203043292 42456.77314715002 36840.46459515533 39838.91496922952 34985.118684015404 35795.90363533765 36268.54649797962 37029.75048972501 34281.42827453916 1.2371496929057901 1.0501152910589124 1.2384773705208396 1.0746478909840746 1.1621136275356971 1.0205268696461773 1.044177720620914 1.0579648609599004 1.0801694198146066 1.0 15.065139597566642 -6.758377711297589 24.999997717004295 1.0444161937842573 1.14726402029604 0.4682086945088205 0.05944427726755492 74.43060827562532 607763.8114561995 0.018615080067198475 0.017860525954444675 1.7443044498184526e-07 6.758377711297589 0.1028478265117827 HIADLAGNSEVILPVPAFNVINGGSHAGNK ddPTM_PC-9_AZD4547_30min_R2 2 HIADLAGNSEVILPVPAFNVINGGSHAGNK 30 0 P06733;A0A2R8Y6G6;P06733-2;K7EM90;A0A2R8YEM5 P06733 ENO1 Alpha-enolase;Enolase 0 ; 108.22 1.5914000000000002e-15 9992800.0 73421.0 71056.0 95540.0 143530.0 122650.0 102832.0 80900.0 116507.0 88780.0 95115.0 False True 96767.35074832955 94023.4624241867 94273.07717527305 110441.37601639464 105622.16459310582 96401.89878401125 88099.94327593349 98503.52021451925 93472.72955203788 91785.0528007527 1.054282236546646 1.0243875179577784 1.0271070757013274 1.2032610174135994 1.1507556118357394 1.050300630030478 0.9598506574614184 1.0731978378696476 1.0183872722168477 1.0 16.48597160937586 -6.996190071317462 24.892271317992893 1.0169754555746695 1.0917596184751353 0.29756612146868433 0.05722844809886035 158.59590954511935 1036177.197716613 0.022358843738485772 0.019631566497077656 1.008811277762276e-07 6.996190071317462 0.07478416290046574 HIADLAGNSEVILPVPAFNVINGGSHAGNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HIADLAGNSEVILPVPAFNVINGGSHAGNK 30 0 P06733;A0A2R8Y6G6;P06733-2;K7EM90;A0A2R8YEM5 P06733 ENO1 Alpha-enolase;Enolase 0 98.23 1.0112e-12 17547000.0 46867.0 57894.0 56566.0 58323.0 90866.0 64440.0 64636.0 67264.0 59125.0 56837.0 False True 54800.65743455591 63641.333711883235 57914.747967749616 55055.3513957172 73061.45958703876 61060.652959863306 58513.2101558842 65498.39127209907 59989.59127148941 67141.09817855556 0.8162013866502245 0.9478744828187793 0.8625826734875661 0.8199948003427434 1.0881779054721228 0.9094378051052744 0.8714961736293575 0.9755335115000969 0.8934854046020012 1.0 16.034908513900955 HIADLAGNSEVILPVPAFNVINGGSHAGNK ddPTM_PC-9_Lapatinib_30min_R1 3 HIADLAGNSEVILPVPAFNVINGGSHAGNK 30 0 P06733;A0A2R8Y6G6;P06733-2;K7EM90;A0A2R8YEM5 P06733 ENO1 Alpha-enolase;Enolase 0 ;; 149.94 4.3571000000000005e-15 12481800.0 56585.0 48206.0 47787.0 45611.0 53146.0 48220.0 45052.0 39683.0 53774.0 45199.0 False True 55778.087523581846 48094.38196876781 43858.13732315443 48965.38509383565 50020.05676905616 46157.74300631013 47384.57211887098 41526.81704991384 47717.40585467635 53011.58692611826 1.0521867153556304 0.9072428266634706 0.8273311527964461 0.9236732558502396 0.9435683719253422 0.8707104556337792 0.8938531152615824 0.78335359225879 0.9001316244537187 1.0 15.694020108542947 -6.772842562453266 24.453362307862648 0.8763345554199774 0.92334745557564 0.0566551441354467 0.07164528700721194 446.6151292812436 957728.9763635559 0.025181667161772323 0.02240648247673846 1.6871645342062279e-07 6.772842562453266 0.04701290015566262 HIAEDADR ddPTM_PC-9_AZD4547_30min_R2 4 HIAEDADR 8 0 P09493-3;P09493-4;P09493-10;P09493-9;P09493;P09493-8;Q6ZN40;H0YKX5;A0A0S2Z4G6;H7BYY1;P09493-2;B7Z596;F5H7S3;P09493-7;A0A494BZZ2;H0YK48;P09493-5;P09493-6;H0YKJ4;H0YL42;A0A494C0V8 P09493-3 TPM1 Tropomyosin alpha-1 chain 0 ;;; 131.22 0.003117 21681100.0 14409.800000000001 14121.000000000002 18888.100000000002 22121.399999999998 24192.6 19398.1 17450.4 20948.9 24104.899999999998 24913.699999999997 False True 18991.816657540436 18685.337098794476 18637.631452734706 17021.65300222302 20833.875084673262 18185.1337404906 19003.451794095818 17711.7288628318 25379.035802871316 24041.478946140105 0.7899604138367535 0.7772124643685631 0.775228158570794 0.7080118922948321 0.8665804267427637 0.756406616299712 0.7904443747686682 0.7367154451068179 1.0556353816555015 1.0 14.553238027787936 -8.263001206687486 24.999950065214634 1.027817722556662 0.7758521073288684 0.8595116453340425 0.04087248976195518 44.91316305174143 718883.7994896781 0.031638923475912385 0.009826628098973876 5.457563447048239e-09 8.263001206687486 -0.2519656152277936 HIAEDADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HIAEDADR 8 0 P09493-3;P09493-4;P09493-10;P09493-9;P09493;P09493-8;Q6ZN40;H0YKX5;A0A0S2Z4G6;H7BYY1;P09493-2;B7Z596;F5H7S3;P09493-7;A0A494BZZ2;H0YK48;P09493-5;P09493-6;H0YKJ4;H0YL42;A0A494C0V8 P09493-3 TPM1 Tropomyosin alpha-1 chain 0 ;;; 125.31 0.0027843000000000004 22272000.0 20544.199999999997 22691.4 22977.9 18098.2 28267.8 29434.5 18582.800000000003 25885.3 29849.4 23868.199999999997 False True 24021.927293554163 24944.052229761775 23525.780280171035 17084.216529156063 22728.927512100185 27890.90300352417 16822.502656178673 25205.83830274243 30285.8910054832 28195.315719432743 0.8519829156230302 0.8846878140318133 0.8343861269110253 0.6059239307393639 0.806124241993679 0.9892034294299898 0.5966417550906971 0.8939725503896412 1.0741461917594204 1.0 14.783167877290936 -8.004543861028766 24.65703259659232 1.0194019189622328 0.7970639446835321 0.41569446445387004 0.11365015644346589 155.15615438433605 841940.8084643508 0.06531576191213932 0.03007238054154652 9.895919162225643e-09 8.004543861028766 -0.2223379742787006 HIAEDADR ddPTM_PC-9_Lapatinib_30min_R1 4 HIAEDADR 8 0 P09493-3;P09493-4;P09493-10;P09493-9;P09493;P09493-8;Q6ZN40;H0YKX5;A0A0S2Z4G6;H7BYY1;P09493-2;B7Z596;F5H7S3;P09493-7;A0A494BZZ2;H0YK48;P09493-5;P09493-6;H0YKJ4;H0YL42;A0A494C0V8 P09493-3 TPM1 Tropomyosin alpha-1 chain 0 ;;; 174.52 0.0012795 32500700.0 8415.300000000001 19583.9 15116.9 5541.5 19244.8 10637.3 13907.8 18621.399999999998 10106.5 5600.4 False True 8295.296278822989 19538.554682781225 13874.046834921488 5949.040395902091 18112.858700732548 10182.367475757412 14627.877832611961 19486.618224762904 8968.19954383692 6568.4216779360695 1.262905563247812 2.974619420128434 2.1122344933373696 0.9057031791800857 2.7575663666014774 1.55020002902081 2.2270004195602033 2.966712428073892 1.3653507621110752 1.0 12.68133103253593 -5.532463030315297 24.942226431290642 1.9168084460323067 2.2249289349295314 0.0167509565727606 0.7546055260982205 828.3937473901505 2155812.867516184 0.19757854326257346 0.34275979436580256 2.9345192967583894e-06 5.532463030315297 0.30812048889722465 HIAEEADR ddPTM_PC-9_AZD4547_30min_R2 4 HIAEEADR 8 0 A0A087WWU8;P06753-5;P06753-2;P06753-4;P06753-3;P06753-6;P06753-7;A0A2R8YGX3;A0A2R8Y5V9;P67936;A0A2R8YH90;A0A2R8YEU4;A0A2R8YE05;K7ENT6;A0A2R8YHD2;P67936-2;A0A5F9UN72;J3KN67;A0A494C0P6;A0A2R2Y2Q3;P06753 A0A087WWU8;A0A2R8YGX3;J3KN67 TPM3;TPM4 Tropomyosin alpha-3 chain;Tropomyosin alpha-4 chain 0 ;;; 176.09 0.0011871 169136000.0 41204.8 36103.8 53997.5 53961.0 64497.0 50839.0 50664.9 53537.5 40403.3 50727.4 False True 54307.0692869174 47773.64730171065 53281.45786866024 41521.12513913934 55542.704849258495 47660.02929321948 55173.9779490834 45264.50954436071 42538.93595302824 48951.44916621888 1.1094067736894377 0.975939387197529 1.0884551688702502 0.848210335880982 1.1346488366597367 0.9736183525718661 1.127116334426288 0.924681706371167 0.8690025867994959 1.0 15.57906394977618 -7.870530845495575 12.617755051307816 0.9220129245053078 1.0304868568096353 0.2264772595111415 0.0883757988011887 0.6908836541034656 75.87707437178723 0.045063997053565716 0.021643677139621887 1.3473150297337263e-08 7.870530845495575 0.10847393230432745 HIAEEADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HIAEEADR 8 0 A0A087WWU8;P06753-5;P06753-2;P06753-4;P06753-3;P06753-6;P06753-7;A0A2R8YGX3;A0A2R8Y5V9;P67936;A0A2R8YH90;A0A2R8YEU4;A0A2R8YE05;K7ENT6;A0A2R8YHD2;P67936-2;A0A5F9UN72;J3KN67;A0A494C0P6;A0A2R2Y2Q3;P06753 A0A087WWU8;A0A2R8YGX3;J3KN67 TPM3;TPM4 Tropomyosin alpha-3 chain;Tropomyosin alpha-4 chain 0 ;;; 145.16 0.0012343 165193000.0 36894.4 45073.3 43112.3 44121.1 56701.0 39379.3 56919.100000000006 42507.4 42468.1 25978.5 False True 43139.893222384155 49547.87934493778 44140.26073630825 41649.1378095362 45590.84608153425 37314.18018470434 51527.31078940202 41391.62579031318 43089.11562074818 30688.196404307168 1.4057487332924317 1.614558206424396 1.438346527595641 1.3571712478903009 1.4856150384626532 1.215913105257212 1.679059600327963 1.3487800079545813 1.404094103578551 1.0 14.905396238288896 -9.111701885160995 1.2956272679616598 0.999860784389568 1.4484238736107622 0.5301823319426211 0.12467492316502454 2.448655579579709 4.6719821851363115 0.11574804480272356 0.03425360452976081 7.732111620088505e-10 9.111701885160995 0.44856308922119414 HIAEEADR ddPTM_PC-9_Lapatinib_30min_R1 4 HIAEEADR 8 0 A0A087WWU8;P06753-5;P06753-2;P06753-4;P06753-3;P06753-6;P06753-7;A0A2R8YGX3;A0A2R8Y5V9;P67936;A0A2R8YH90;A0A2R8YEU4;A0A2R8YE05;K7ENT6;A0A2R8YHD2;P67936-2;A0A5F9UN72;J3KN67;A0A494C0P6;A0A2R2Y2Q3;P06753 A0A087WWU8;A0A2R8YGX3;J3KN67 TPM3;TPM4 Tropomyosin alpha-3 chain;Tropomyosin alpha-4 chain 0 ;;; 188.76 1.9366e-05 175390000.0 64997.9 60973.6 69215.2 61284.7 62129.9 55772.3 54213.7 53044.0 74457.0 53730.6 False True 64071.01802684494 60832.419375406804 63524.59343439839 65791.7812777661 58475.54143408316 53387.048740581275 57020.62011632858 55508.617886642394 66070.86859303075 63017.86261847586 1.0167120140958306 0.9653202575863257 1.0080410663717745 1.0440179743334705 0.9279201008150194 0.8471732699631266 0.904832657710784 0.8808394252071654 1.0484466760327698 1.0 15.943473202739908 -6.318573893180062 9.23299438204802 0.9229054581916102 1.005359421898078 0.26991221061899817 0.057264614518076816 0.5715406858500628 89.2909011130323 0.017806410461324258 0.02021262028950583 4.802043687553391e-07 6.318573893180062 0.08245396370646774 HIALS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 HIALSPR 7 0 Q3B726 Q3B726 TWISTNB DNA-directed RNA polymerase I subunit RPA43 1 HIALS(1)PR;HIALS(1)PR;HIALS(1)PR 91.265 0.0087123 22405900.0 19222.5 23184.5 28209.199999999997 42598.3 34594.0 37020.0 28749.3 39435.8 32168.1 33676.5 True False 25334.855147161717 30678.436227391863 27835.127576436145 32777.92007217433 29791.220235906294 34705.13354776819 31307.932005226176 33341.903254531855 33868.44009352226 32497.495985328846 0.7795940696046016 0.9440246178118399 0.8565314567313879 1.0086290982841288 0.9167235607739035 1.0679325435853888 0.9633952111067355 1.0259837640901386 1.042186145936054 1.0 14.988040938652938 -3.050535321813167 0.3943911934016178 1.0246320553633887 1.3442276597182994e-09 0.643038951173885 0.05073568145050737 13.013679569363564 0.5366546709433841 0.03567529184844895 8.367839538863564 0.0008901530376016546 3.050535321813167 -1.0246320540191611 HIALS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HIALSPR 7 0 Q3B726 Q3B726 TWISTNB DNA-directed RNA polymerase I subunit RPA43 1 HIALS(1)PR;HIALS(1)PR;HIALS(1)PR;HIALS(1)PR 81.97200000000001 0.013127000000000002 14807600.0 29537.8 23768.699999999997 31168.7 31678.5 34787.8 29074.5 32426.699999999997 38050.3 24360.2 26437.899999999998 True False 34537.96614185726 26128.299454134085 31911.88001595299 29903.656348082706 27971.380316311817 27549.782037267934 29355.008227022245 37051.51994262536 24716.421840029354 31230.881987698736 1.105891474837666 0.836617405311369 1.0218052768577746 0.9575027807367464 0.8956320966961235 0.8821326931503017 0.9399352934888178 1.1863744340367737 0.7914096646314598 1.0 14.930685692465781 HIALS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 HIALSPR 7 0 Q3B726 Q3B726 TWISTNB DNA-directed RNA polymerase I subunit RPA43 1 HIALS(1)PR;HIALS(1)PR;HIALS(1)PR 81.95 0.013144 35727000.0 43617.9 33565.5 42061.6 38039.0 44885.7 47072.4 37025.5 34054.1 45897.2 33807.2 True False 42995.90074745679 33487.78114700817 38603.45761047132 40836.51495438411 42245.611374681524 45059.223183123846 38942.49922283714 35636.377806604134 40727.7740170575 39650.72947473759 1.0843659452684342 0.8445691060575322 0.9735875763664446 1.0299057670654461 1.0654434845037892 1.136403384755686 0.9821382793889912 0.8987571799734203 1.027163297033567 1.0 15.27505978772096 -4.473707680296746 23.288144891596797 0.9967374893966298 2.3082855711849612 0.10640464104698466 0.07730976510722039 402.9906379030344 567857.1464973041 0.020065489332121666 52241.10112961976 3.359636722767536e-05 4.473707680296746 1.3115480817883314 HIDCAYVYQNEHEVGEAIQEK ddPTM_PC-9_Lapatinib_30min_R1 2 HIDCAYVYQNEHEVGEAIQEK 21 0 O60218 O60218 AKR1B10 Aldo-keto reductase family 1 member B10 0 ; 109.77 1.7658e-05 24972000.0 89188.0 78126.0 96843.0 81929.0 87885.0 87609.0 92075.0 72897.0 83680.0 80409.0 False True 87916.16276492394 77945.10404704703 88880.94236479049 87954.33196713211 82715.77708855788 83862.16729655379 96842.19297356499 76284.06074358233 74255.07721053522 94307.58851174255 0.9322278742603752 0.8264987502818167 0.9424580117826217 0.9326326052349502 0.8770850616995541 0.8892409255710301 1.0268759333349602 0.8088857105500471 0.7873711795874144 1.0 16.525086242366918 -10.693444559414433 7.455774390877616 1.0000000697961196 0.8933383869224497 0.18548019036380792 0.0681257969053589 8.021957079950138e-08 8.896688713857598e-09 0.06693898344430863 0.016235077665393848 2.0256081727064878e-11 10.693444559414433 -0.10666168287366984 HIDFSLR ddPTM_PC-9_AZD4547_30min_R2 2 HIDFSLR 7 0 P46781 P46781 RPS9 40S ribosomal protein S9 0 ; 177.71 0.00012138 26951000.0 11779.2 18474.1 26524.8 30897.0 18876.9 22917.2 22959.4 19948.7 20289.9 27752.8 False True 15524.740577419561 24445.491544284334 26173.063821003554 23774.174003891498 16256.168274012247 21484.183861180783 25002.742121748688 16866.086790522306 21362.382691348168 26781.18291929488 0.5796883813610244 0.9127861012693445 0.9772930456386526 0.8877193391918122 0.6069996356397037 0.8022119084852747 0.9335936428609026 0.6297737796477577 0.7976638954195462 1.0 14.70893206515977 -4.748772547868654 24.580877206550646 0.8275536011134702 0.5796876590785595 0.2658997220450082 0.127900422548748 747.0559407510175 1449606.1659375145 0.03285182473017342 0.5675488981621867 1.783312493401628e-05 4.748772547868654 -0.24786594203491075 HIDFSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HIDFSLR 7 0 P46781 P46781 RPS9 40S ribosomal protein S9 0 ;;; 158.36 0.00038469 17880500.0 8417.4 13252.499999999998 11805.1 10158.2 15888.5 14280.0 10711.6 12153.0 9979.7 8958.560000000001 False True 9842.299568771858 14568.1206172787 12086.578355091067 9589.068987328743 12775.262481551585 13531.131661496722 9696.919702731742 11833.996627167875 10125.634232762493 10582.676012078058 0.9300388254859919 1.3766008333480149 1.1421098351018777 0.9061100402568021 1.2071863928340163 1.2786115389012738 0.9163012920044611 1.1182423626747788 0.9568122676349592 1.0 13.369416863447023 -7.273147023636149 24.874832882085467 1.0076925192697948 1.1433627086814044 0.19257374546692596 0.14205098708127495 1318.9356844978463 2802286.8320911624 0.05916923526527807 0.040267553754002934 5.3315437381934814e-08 7.273147023636149 0.1356701894116097 HIDFSLR ddPTM_PC-9_Lapatinib_30min_R1 2 HIDFSLR 7 0 P46781 P46781 RPS9 40S ribosomal protein S9 0 ; 148.33 0.0010174 18553000.0 15678.9 11475.8 14046.0 12498.400000000001 14428.0 14584.2 12123.6 11439.3 11829.0 10008.9 False True 15455.316010841882 11449.228490171054 12891.192099127946 13417.574029440175 13579.373406539393 13960.467763430688 12751.300686769619 11970.811639217787 10496.693455107788 11738.925028979065 1.3165869935013998 0.9753217148850634 1.0981578012726343 1.1429985280864428 1.156781679158606 1.1892458405661042 1.0862409168890144 1.0197536494752526 0.8941784217205011 1.0 13.519012681833255 -7.8160558840614 2.4707117214658503 0.9492365095261415 1.1363867348488412 0.4722603848610042 0.08378837928783499 0.26117883464031366 3.1525393437339173 0.05542663355941806 0.023024520596858666 1.5273695070342467e-08 7.8160558840614 0.18715022532269976 HIDLVEGDEGR ddPTM_PC-9_AZD4547_30min_R2 2 HIDLVEGDEGR 11 0 P19367-4;P19367-2;P19367;P19367-3 P19367-4 HK1 Hexokinase-1 0 ; 138.63 8.6603e-05 8763900.0 49714.0 47519.0 67578.0 85002.0 66617.0 67060.0 59134.0 74034.0 52758.0 56558.0 False True 65522.01788456227 62878.58746530803 66681.87156531925 65406.102167808654 57368.379443122256 62866.72759895555 64396.81144226274 62593.746432074724 55546.680172408334 54577.92163491541 1.2005224076294898 1.1520883460150377 1.2217737423453026 1.198398550339192 1.051127960256033 1.1518710444762978 1.1799058944206084 1.1468693668985612 1.0177500078506687 1.0 15.736029836380421 -8.263307188901098 3.6897714015973295 1.000670747162303 1.163309322564901 0.6667049771106452 0.043775417518219686 0.141806297037864 4.083048030622101 0.04096278069766989 0.011959940004878293 5.4537196744884955e-09 8.263307188901098 0.16263857540259785 HIDLVEGDEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HIDLVEGDEGR 11 0 P19367-4;P19367-2;P19367;P19367-3 P19367-4 HK1 Hexokinase-1 0 ;; 119.03 0.00084385 7525800.0 69825.0 68152.0 72250.0 82228.0 91088.0 82305.0 81823.0 80313.0 77805.0 58339.0 False True 81644.99339338699 74917.68015912303 73972.71400965098 77621.03174677283 73239.96028067918 77988.78091032816 74072.13309277993 78204.86884865741 78942.7509324012 68915.39888873018 1.184713354488593 1.0870963727581995 1.0733843988784897 1.1263234777484004 1.0627517428859605 1.1316597185521298 1.0748270239627538 1.1347952723153483 1.145502343530813 1.0 16.072538763323593 -11.056871771820312 2.8897248678066814 0.9950338104295202 1.1104117391439394 0.45994953777217873 0.036747347042467154 25759352.171222568 28816686.552918054 1005453.826401194 0.009106649685226838 8.772597993874401e-12 11.056871771820312 0.11537792871441921 HIDLVEGDEGR ddPTM_PC-9_Lapatinib_30min_R1 4 HIDLVEGDEGR 11 0 P19367-4;P19367-2;P19367;P19367-3 P19367-4 HK1 Hexokinase-1 0 ;;; 131.12 0.00014684 9883700.0 92535.0 91674.0 95962.0 74891.2 75103.2 81707.0 74764.5 75788.9 89392.0 63301.4 False True 91215.43393115918 91461.73448543355 88072.37478403229 80398.94867771954 70685.77743457224 78212.58207831977 78635.4399844919 79310.32897498205 79323.73162050861 74242.9626461864 1.2286071390477384 1.2319246326591955 1.1862723636683465 1.082916761563924 0.9520872405299027 1.0534679556236335 1.059163551422892 1.0682538270050563 1.0684343511254422 1.0 16.179966661535403 -5.758861617097695 2.9098615004880317 1.0377774481083961 1.2260894524282513 0.8499481213165969 0.034412249311871736 0.09583760676061674 1.661240770409904 0.010502762095736898 0.018551247836658936 1.7423619683933442e-06 5.758861617097695 0.18831200431985518 HIDSAHLYNNEEQVGLAIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HIDSAHLYNNEEQVGLAIR 19 0 A0A0A0MSS8;P42330;S4R3Z2;S4R3D5;A6NHU4;Q04828 A0A0A0MSS8;Q04828 AKR1C3;AKR1C1 Aldo-keto reductase family 1 member C3;Aldo-keto reductase family 1 member C1 0 70.78399999999999 0.0028515 2438200.0 1944.1 7125.9 6372.4 11794.0 9948.9 10093.0 8983.4 8772.2 10818.0 7706.5 False True 2273.197732274738 7833.312258567533 6524.3421834615765 11133.2204166639 7999.484463776225 9563.705312288965 8132.427317816233 8541.93904491419 10976.192784354711 9103.627445379565 0.24970241213336028 0.8604605477944107 0.7166749982473115 1.2229433248956636 0.8787139535061121 1.0505378619313894 0.8933172371793122 0.9383005945887589 1.2056944168915373 1.0 13.152225803016037 -4.730184099213625 1.5282762296250907 0.9991953571381441 7.100165884459097e-25 0.7026026742723699 0.14329094700229442 0.6912419563671253 1.3895546370384353 0.03838054061600562 1.088258040173457 1.861297957561855e-05 4.730184099213625 -0.9991953571381441 down HIDSSPYSPAY(ph)LSPPPESSWR ddPTM_PC-9_Lapatinib_30min_R1 1 HIDSSPYSPAYLSPPPESSWR 21 0 Q53ET0;H0YDQ8 Q53ET0 CRTC2 CREB-regulated transcription coactivator 2 1 HIDSSPYSPAY(0.808)LS(0.192)PPPESSWR 126.96 6.1779e-06 3914100.0 21968.0 18087.0 25780.0 17367.0 27487.0 32010.0 28553.0 30749.0 39273.0 26297.0 True False 21654.732291562184 18045.12066276196 23660.467913677814 18644.227114613663 25870.268701521214 30641.006918954514 30031.33462909802 32177.710794743365 34849.661176975926 30842.40141145006 0.7021091517057745 0.5850750861462692 0.7671409109179808 0.6044998528451841 0.8387890539521033 0.9934702071408493 0.9737028653660238 1.0432945984159838 1.1299269700847028 1.0 14.912627478444168 -6.605412190536878 2.00159424824734 1.0379766260295256 0.6633346374373644 0.8841239415873401 0.06198020097963411 0.10023295091638755 0.8187349740948233 0.023001907490648437 0.023519305158051954 2.4807774723118855e-07 6.605412190536878 -0.37464198859216113 HIDSSPYSPAYLS(ph)PPPESSWR ddPTM_PC-9_AZD4547_30min_R2 2 HIDSSPYSPAYLSPPPESSWR 21 0 Q53ET0;H0YDQ8 Q53ET0 CRTC2 CREB-regulated transcription coactivator 2 1 HIDSSPYSPAY(0.005)LS(0.993)PPPES(0.001)S(0.001)WR;HIDSSPYSPAY(0.002)LS(0.998)PPPESSWR 153.65 1.028e-05 14132600.0 13212.3 9706.2 19369.4 29124.0 27346.0 23824.1 14409.900000000001 22086.0 18110.7 18273.8 True False 17413.53656708778 12843.539334913889 19112.549100258864 22409.91176131454 23549.479926319415 22334.375260815334 15692.353184324787 18673.116185790343 19067.994628273154 17634.039824111827 0.9874955903908903 0.7283378887095588 1.0838440476994615 1.2708325480059564 1.335455752692536 1.2665489861419346 0.8898898573920604 1.0589244649576972 1.081317430291873 1.0 14.106075402509257 -5.4072063128534475 6.009160053484289 1.1387017674353017 0.8610442557509407 0.36518649779473655 0.1404529829278021 0.24388036762476448 11.107151615042916 0.04005085195319377 0.0845646871953881 3.915558231889079e-06 5.4072063128534475 -0.27765751168436104 HIDSSPYSPAYLS(ph)PPPESSWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HIDSSPYSPAYLSPPPESSWR 21 0 Q53ET0;H0YDQ8 Q53ET0 CRTC2 CREB-regulated transcription coactivator 2 1 HIDSSPYSPAYLS(1)PPPESSWR 150.26 4.1606e-05 4608800.0 20100.0 23077.0 30563.0 29261.0 30247.0 28386.0 32013.0 33768.0 25737.0 24237.0 True False 23502.53300690408 25367.93204942014 31291.737830822945 27621.60103544195 24320.317479906284 26897.388189302932 28980.496885950895 32881.62578015348 26113.35493537966 28630.976240013577 0.8208778076542784 0.886030983951112 1.092932967723636 0.9647453444789995 0.8494407342602982 0.9394506133434651 1.01220777953945 1.1484633113627245 0.9120665225129353 1.0 14.805289242782782 -7.285467504879751 4.6047000623313865 1.0321805742658985 0.9292622355032891 0.2059006408632541 0.08787330393282043 0.32726408715330507 18.08959632400024 0.03845153691920587 0.026493566042077626 5.182418668535092e-08 7.285467504879751 -0.10291833876260936 HIDSSPYSPAYLS(ph)PPPESSWR ddPTM_PC-9_Lapatinib_30min_R1 1 HIDSSPYSPAYLSPPPESSWR 21 0 Q53ET0;H0YDQ8 Q53ET0 CRTC2 CREB-regulated transcription coactivator 2 1 HIDSSPYSPAYLS(0.999)PPPESSWR 124.88 3.1006e-06 4246000.0 5952.3 5492.4 9117.3 9081.8 7985.8 11050.0 9361.1 9045.0 10357.0 6940.7 True False 5867.41911048187 5479.682685252053 8367.71078779576 9749.705867996681 7516.090944686874 10577.417258808111 9845.771953785928 9465.263720395913 9190.485595954977 8140.3907470985805 0.7207785587655177 0.6731473777478232 1.0279249544351667 1.1976950702853788 0.9233083740317722 1.299374635373387 1.209496234231162 1.1627529948448172 1.1289980888485818 1.0 12.990882331656234 -5.362961297507126 3.43774078409041 1.1391027565886305 0.6920002069703357 0.7375539480984747 0.10186649776523815 0.11259042753082059 2.460435531800756 0.027284955223829892 0.06528744437717958 4.33549512770403e-06 5.362961297507126 -0.44710254961829476 HIEALLGS(ph)PCGK ddPTM_PC-9_AZD4547_30min_R2 2 HIEALLGSPCGK 12 0 P49589-3;E9PLP0 P49589-3 CARS Cysteine--tRNA ligase, cytoplasmic 1 HIEALLGS(1)PCGK;HIEALLGS(1)PCGK 64.407 0.024978 15952400.0 103323.0 98964.0 113494.0 156053.0 139605.0 138941.0 100704.0 127148.0 112199.0 118266.0 True False 136177.56474809136 130952.17765350151 111988.99540433775 120077.39184481601 120223.25550770943 130252.997305793 109666.4609105022 107500.19817037373 118129.61008120165 114125.54333736889 1.1932259927607445 1.1474396863670655 0.981278968138489 1.0521517649195566 1.0534298632192705 1.1413132721808772 0.960928269899359 0.9419468685690298 1.0350847551454476 1.0 16.800262203152435 -1.5228787452886667 0.548818942634421 1.0105128473611849 9.583429666213737 0.5025606911276929 0.05704268456203633 119.69357999719585 1.100394070005013 0.030430149417236638 1209.0329152409543 0.02999999999942464 1.5228787452886667 8.572916818852553 HIEALLGS(ph)PCGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HIEALLGSPCGK 12 0 P49589-3;E9PLP0 P49589-3 CARS Cysteine--tRNA ligase, cytoplasmic 1 HIEALLGS(1)PCGK;HIEALLGS(1)PCGK 119.25 0.0016905000000000002 3492500.0 36296.0 32208.0 41674.0 40878.0 52149.0 39845.0 40746.0 37574.0 37216.0 30901.0 True False 42440.195921322884 35405.39738474342 42667.66620952512 38587.738188264135 41930.777804728794 37755.458056886324 36886.24390450612 36587.7223129438 37760.21359424521 36503.10668781857 1.1626461354174433 0.9699283320605294 1.168877667712697 1.057108331032581 1.1486906625052133 1.0343080762900019 1.0104960166805586 1.0023180390055257 1.0344383538962219 1.0 15.155731632922324 -6.940996802305121 7.830435666706744 1.0134358228837217 1.0953461583313953 0.37353844479329634 0.055436564244585866 0.27250735275362825 31.436439245745145 0.01836442259336172 0.01617193736072056 1.1455213758477776e-07 6.940996802305121 0.08191033544767357 HIEALLGS(ph)PCGK ddPTM_PC-9_Lapatinib_30min_R1 1 HIEALLGSPCGK 12 0 P49589-3;E9PLP0 P49589-3 CARS Cysteine--tRNA ligase, cytoplasmic 1 HIEALLGS(1)PCGK 63.754 0.026191000000000002 7343700.0 47390.0 37041.0 43114.0 41684.0 40848.0 39954.0 35468.0 37719.0 43860.0 30511.0 True False 46714.209909738376 36955.23384029227 39569.3333448528 44749.58041374766 38445.40095025792 38245.26055732301 37304.35949374314 39471.56243997937 38920.02493372458 35784.785696648 1.305420977108552 1.0327079824807754 1.105758566791118 1.250519726262868 1.0743504593310766 1.068757568692258 1.042464241926073 1.1030263748003026 1.087613749140609 1.0 15.127058719402255 -6.480903095278382 24.417370065295273 1.066343559582538 1.1591599523143516 0.3411815453265109 0.0744017952518036 510.76351962024904 297112.6446174925 0.022702771875493234 0.02573963045570222 3.3044326506903236e-07 6.480903095278382 0.09281639273181375 HIELGVT(ph)GGGSPENGDGALLAITPPAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HIELGVTGGGSPENGDGALLAITPPAVK 28 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 HIELGVT(0.59)GGGS(0.409)PENGDGALLAITPPAVK 72.687 0.00015622 5614000.0 39422.0 45698.0 37302.0 37557.0 45127.0 42616.0 54508.0 44662.0 39793.0 39767.0 True False 46095.36598000857 50234.59543243931 38191.42114862276 35452.803051436844 36284.68829688001 40381.14193881961 49344.60763625437 43489.66982330059 40374.89734404022 46976.44230460124 0.9812442943448196 1.0693571707008331 0.8129909221516759 0.7546932315894923 0.7724017936821497 0.8596040900028814 1.0504117641837933 0.9257761484215434 0.8594711596558172 1.0 15.519649836538093 -9.369494921966881 13.870660543335475 1.000000003480957 0.8971496130905987 0.0798487499650421 0.10334601119123298 0.0 0.0 0.11150806635310546 0.02704467856954333 4.270759130408078e-10 9.369494921966881 -0.10285039039035837 HIELGVTGGGS(ph)PENGDGALLAITPPAVK ddPTM_PC-9_AZD4547_30min_R2 1 HIELGVTGGGSPENGDGALLAITPPAVK 28 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 HIELGVT(0.318)GGGS(0.682)PENGDGALLAITPPAVK 70.112 8.7734e-05 9034800.0 21789.0 18224.0 22981.0 32496.0 26383.0 25375.0 23800.0 31364.0 20899.0 23108.0 True False 28717.44876064544 24114.551610256378 22676.256924481353 25004.549258195213 22720.175853729423 23788.29723864445 25918.153893290717 26517.414473020395 22003.678473845895 22298.995953527796 1.2878359555064278 1.0814187177087384 1.0169182940675798 1.1213307231547969 1.0188878414561529 1.0667878180802592 1.162301385555898 1.1891752672758895 0.9867564674078888 1.0 14.44469113160189 -1.5228787455579573 0.011858275322226726 9.939952270797492e-09 2.3611404471568394 0.18451682400135339 0.0831851196134118 20773.488241056686 19.109876809716397 1595.048180541309 2264.1014002071693 0.029999999980822707 1.5228787455579573 2.361140437216887 HIEPELAGRDS(ph)PIR ddPTM_PC-9_AZD4547_30min_R2 2 HIEPELAGRDSPIR 14 1 P86791;P86790 P86791 CCZ1;CCZ1B Vacuolar fusion protein CCZ1 homolog;Vacuolar fusion protein CCZ1 homolog B 1 HIEPELAGRDS(1)PIR;HIEPELAGRDS(1)PIR 91.616 0.0021086 35528000.0 63184.0 64206.0 75754.0 77367.0 80515.0 72308.0 61139.0 73025.0 71422.0 66247.0 True False 83275.1976911571 84959.3338832376 74749.45246321561 59531.2334582345 69336.8820400646 67786.56932933613 66580.2525580631 61740.66419756132 75197.22110909704 63927.71269401746 1.3026462887815824 1.328990672478547 1.1692808848174367 0.9312273339603719 1.084613841448348 1.0603628140707715 1.0414928010445441 0.9657887259798549 1.1762851811861277 1.0 15.964153855308451 -5.484447524471833 3.9295409781142827 1.0386133075836719 1.3103092289830698 0.7504194719386525 0.06426572941501034 0.09949609180546701 3.256607318838799 0.016718869195564878 0.0351923858444232 3.277573771297147e-06 5.484447524471833 0.2716959213993979 HIEPELAGRDS(ph)PIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HIEPELAGRDSPIR 14 1 P86791;P86790 P86791 CCZ1;CCZ1B Vacuolar fusion protein CCZ1 homolog;Vacuolar fusion protein CCZ1 homolog B 1 HIEPELAGRDS(1)PIR 54.073 0.037763 12769000.0 50083.0 52224.0 59926.0 62916.0 60609.0 55346.0 65799.0 51856.0 57818.0 47268.0 True False 58561.06271566057 57408.45358360781 61354.86311062058 59391.02049642414 48733.10153534695 52443.55832893541 59566.04237649337 50494.83494597367 58663.47886909043 55837.31422671785 1.0487800770266889 1.0281378031635013 1.0988147256062437 1.0636439327163387 0.8727694411925785 0.9392206458211318 1.0667784294680733 0.9043206258264508 1.0506142654157296 1.0 15.768941929173996 -6.134901172068796 18.41071388194839 0.970320483861177 1.0604017896041171 0.34991625678032234 0.05842566353662175 2.7940438513875985 397.6071453417322 0.017020087559922046 0.02197305772472583 7.32991313460848e-07 6.134901172068796 0.09008130574294015 HIEPELAGRDS(ph)PIR ddPTM_PC-9_Lapatinib_30min_R1 2 HIEPELAGRDSPIR 14 1 P86791;P86790 P86791 CCZ1;CCZ1B Vacuolar fusion protein CCZ1 homolog;Vacuolar fusion protein CCZ1 homolog B 1 HIEPELAGRDS(1)PIR;HIEPELAGRDS(1)PIR 67.32600000000001 0.014571 9136100.0 13161.8 13908.8 15244.5 14800.9 15131.7 13951.3 12330.400000000001 13597.2 18303.4 9878.4 True False 12974.110318421484 13876.595028154117 13991.156055471738 15889.407560354995 14241.683156066816 13354.635421068737 12968.807778889442 14228.975551019048 16241.878348653307 11585.868277859381 1.1198220113735486 1.197717313485457 1.2076053101871413 1.371447282092762 1.2292288169098817 1.1526659116770275 1.1193643383355965 1.2281319975137859 1.4018697571153618 1.0 13.500078547465755 -7.985738937121055 24.960413452558974 1.2389569264615004 1.2035612190035376 0.0 0.11367839138532763 1292.248770454753 2261754.6895271083 0.06163937470516041 0.02959027344484255 1.0333824054032199e-08 7.985738937121055 -0.03539570745796272 HIEPELAGRDS(ph)PIRAEMPGNLQHYGR ddPTM_PC-9_AZD4547_30min_R2 1 HIEPELAGRDSPIRAEMPGNLQHYGR 26 2 P86791;P86790 P86791 CCZ1;CCZ1B Vacuolar fusion protein CCZ1 homolog;Vacuolar fusion protein CCZ1 homolog B 1 HIEPELAGRDS(1)PIRAEMPGNLQHYGR 45.511 0.009611 20966000.0 12316.0 23755.0 25568.0 46106.0 29241.0 25098.0 20582.0 31246.0 26294.0 28816.0 True False 16232.23181128593 31433.339195656303 25228.951614165573 35476.97403059911 25181.391886400437 23528.61809243342 22413.758127382756 26417.64866165015 27683.847159735098 27807.16061090779 0.5837428725073995 1.1304044895301568 0.9072825509652763 1.275821524067535 0.905572209933676 0.8461352247235179 0.8060426751586643 0.9500304267414997 0.9955654065908361 1.0 14.763168818168042 -6.436265050209796 24.55263586950988 0.9055473884151357 0.9944265564222028 0.017273859491444332 0.17503227349997624 220.75553753029408 62572.711578590766 0.053229233891043386 0.060356255845558024 3.6621400578250716e-07 6.436265050209796 0.08887916800706708 HIEPELAGRDS(ph)PIRAEMPGNLQHYGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HIEPELAGRDSPIRAEMPGNLQHYGR 26 2 P86791;P86790 P86791 CCZ1;CCZ1B Vacuolar fusion protein CCZ1 homolog;Vacuolar fusion protein CCZ1 homolog B 1 HIEPELAGRDS(1)PIRAEMPGNLQHYGR 41.597 0.018011000000000003 15767000.0 26417.0 19820.0 20722.0 34672.0 22849.0 22788.0 22516.0 24697.0 24891.0 17664.0 True False 30888.876340466915 21787.59861418328 21216.091068622638 32729.440248140658 18371.90247291892 21592.957164018713 20383.121478276636 24048.7299186345 25254.983785854405 20866.343371852927 1.4803205233425616 1.044150296288762 1.0167613314195478 1.5685278280376678 0.8804562517504234 1.0348222867426753 0.9768420424717001 1.1525129003232242 1.210321489289849 1.0 14.348890183616966 -4.7560125655574925 24.966760332041645 1.1025970512388155 1.48032112975753 0.28933641646858876 0.1795137587163858 230.40146029905048 1059877.0100280398 0.04453246095435603 0.3741933463615869 1.7538297570858878e-05 4.7560125655574925 0.3777240785187146 HIGYDDSSK ddPTM_PC-9_Lapatinib_30min_R1 1 HIGYDDSSK 9 0 P31153-2;P31153 P31153-2;P31153 MAT2A S-adenosylmethionine synthase isoform type-2 0 79.48899999999999 0.016357 0.0 56190.0 76388.0 91957.0 96882.0 97182.0 79828.0 77762.0 79687.0 92057.0 64347.0 False True 55388.720296016014 76211.1282792647 84396.65042428504 104007.02546887772 91465.94582716317 76413.94252815683 81788.13586761185 83389.54893169583 81688.5712568145 75469.29321301203 0.7339239303551099 1.0098296278482275 1.1182912523915594 1.378137001698399 1.2119624013040722 1.0125170022790397 1.0837273331388555 1.1049467323925888 1.0824080600072477 1.0 16.20360214265551 -4.806599650709582 2.383884785820151 1.1334036390077649 0.653785575181772 0.5701028982452833 0.10234295909746573 0.4083868713688073 2.9926786019560105 0.029208944342962805 0.4033511419833679 1.560990820914066e-05 4.806599650709582 -0.4796180638259928 HIISATSLST(ph)SPTELGSR ddPTM_PC-9_AZD4547_30min_R2 1 HIISATSLSTSPTELGSR 18 0 Q5JSZ5;Q5JSZ5-5;A0A1W2PQP5 Q5JSZ5 PRRC2B Protein PRRC2B 1 HIISAT(0.007)S(0.007)LS(0.002)T(0.845)S(0.139)PTELGSR 273.77 4.5353999999999993e-91 6851000.0 18523.0 14679.0 32512.0 51851.0 35357.0 38928.0 24401.0 36343.0 24994.0 32603.0 True False 24412.92869766557 19423.699686509754 32080.86963703657 39897.55303996432 30448.29085624497 36493.82600614585 26572.64172899945 30727.024429058136 26315.1318137377 31461.578893580874 0.7759600616435228 0.6173784142305961 1.019684032563987 1.2681357529740709 0.9677928421595318 1.1599489691724183 0.8446061088949698 0.9766523330883241 0.8364212076815634 1.0 14.94130345350652 -5.269874903472957 24.7470456613629 1.0156021465530674 0.6966692347074809 0.4895001943696893 0.12751143835918166 394.4507281165174 1157191.1111217167 0.03425087854898688 0.07320523240630994 5.371865081889117e-06 5.269874903472957 -0.3189329118455865 HIISATSLST(ph)SPTELGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HIISATSLSTSPTELGSR 18 0 Q5JSZ5;Q5JSZ5-5;A0A1W2PQP5 Q5JSZ5 PRRC2B Protein PRRC2B 1 HIISATSLST(0.576)S(0.416)PT(0.008)ELGSR;HIISATS(0.002)LS(0.068)T(0.557)S(0.353)PT(0.02)ELGSR 174.4 9.5921e-26 5620700.0 25402.6 33455.9 57512.0 49511.0 57083.0 52266.0 49702.0 50715.0 51623.0 35149.6 True False 29702.758455780167 36777.18064965965 58883.304195474564 46737.05918682777 45897.99592374419 49525.078950965515 44993.86674868119 49383.784986984196 52377.88871387903 41521.9442359195 0.7153508585006267 0.885728771290163 1.4181249283730848 1.1255990066668606 1.1053913001510918 1.1927447007195466 1.0836165689408692 1.1893418262496396 1.2614507744694756 1.0 15.341586378010385 -5.050727871709859 6.230403537267342 1.1722486914149706 0.7530921852300176 0.6701665673303697 0.10723207584040624 0.09802222476164944 9.159382007925217 0.026365295337191497 0.07514535672857474 8.897584645820402e-06 5.050727871709859 -0.4191565061849529 HIISATSLST(ph)SPTELGSR ddPTM_PC-9_Lapatinib_30min_R1 2 HIISATSLSTSPTELGSR 18 0 Q5JSZ5;Q5JSZ5-5;A0A1W2PQP5 Q5JSZ5 PRRC2B Protein PRRC2B 1 HIISATS(0.007)LS(0.051)T(0.871)S(0.072)PTELGSR;HIISATSLS(0.008)T(0.567)S(0.425)PT(0.001)ELGSR 161.94 7.069500000000001e-06 55083600.0 56317.0 42885.0 80263.0 61764.0 64346.0 66308.0 55018.0 53124.0 69110.0 48238.0 True False 55513.90925272709 42785.702417346554 73664.08596413975 66306.33059866398 60561.2947891034 63472.161411497575 57866.56283485846 55592.334978696745 61326.10403943692 56575.87402690528 0.9812293704261085 0.7562534941483952 1.3020406176864008 1.1719895050517695 1.0704438213416343 1.1218944913040616 1.0228134134938751 0.9826155748342341 1.0839621144919938 1.0 15.787899347058262 -5.245755481745087 24.999165002904803 1.0941798447690574 0.8687414407133066 0.4432188021722673 0.1011993396987912 761.215945610769 1213327.02827731 0.026389186405606446 0.06928195394720207 5.678642366644239e-06 5.245755481745087 -0.22543840405575077 HIISATSLSTS(ph)PTELGSR ddPTM_PC-9_AZD4547_30min_R2 3 HIISATSLSTSPTELGSR 18 0 Q5JSZ5;Q5JSZ5-5;A0A1W2PQP5 Q5JSZ5 PRRC2B Protein PRRC2B 1 HIISATSLST(0.014)S(0.511)PT(0.474)ELGSR;HIISATS(0.002)LS(0.019)T(0.155)S(0.821)PT(0.002)ELGSR;HIISAT(0.001)S(0.009)LS(0.2)T(0.134)S(0.656)PTELGSR 265.93 3.8964999999999986e-78 61521200.0 88801.0 73839.0 200517.0 265235.0 215491.0 209219.0 136923.0 251289.0 162269.0 196108.0 True False 117037.87082445636 97706.01274965555 197858.0135645198 204089.1685899007 185573.79429541776 196136.50285603787 149108.88174500215 212458.05909676084 170846.20806127097 189242.3186106299 0.61845506694126 0.5163010761387242 1.0455273166020378 1.0784541749872476 0.9806146725418208 1.0364304575003274 0.7879256756085136 1.1226773200443492 0.9027907146540023 1.0 17.52987521651172 -5.261511144895036 24.9999990773875 0.9953344103255919 0.5673780400864336 0.7755979555009319 0.09185435551355375 2.5458778525072145 887265.8756972739 0.02297483705197494 0.053309895258189854 5.476320474100913e-06 5.261511144895036 -0.42795637023915833 HIISATSLSTS(ph)PTELGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HIISATSLSTSPTELGSR 18 0 Q5JSZ5;Q5JSZ5-5;A0A1W2PQP5 Q5JSZ5 PRRC2B Protein PRRC2B 1 HIISATSLS(0.017)T(0.215)S(0.384)PT(0.384)ELGSR;HIISATSLST(0.057)S(0.941)PT(0.003)ELGSR;HIISATSLST(0.031)S(0.964)PT(0.006)ELGSR 297.73 3.961699999999999e-121 62206600.0 69509.0 71113.0 98464.0 121219.0 126099.0 123538.0 118363.0 116664.0 103097.0 86758.0 True False 81275.50083467158 78172.62867055564 100811.75518679945 114427.49242730072 101390.80615924578 117059.44980378012 107150.79976608886 113601.69361572576 104604.59858463821 102486.53862405005 0.7930358652545908 0.7627599655532832 0.9836585032557867 1.1165124119085874 0.9893085230556597 1.142193417549086 1.045510963729087 1.1084547799243105 1.0206667137852885 1.0 16.645074901868014 -5.376262646357748 3.4295875030705867 1.0643177283079477 0.7754407717309723 0.8363453085091233 0.04911646906828332 0.07846744351798045 1.68706802853649 0.012261284069591238 0.029023608688329667 4.20472264320677e-06 5.376262646357748 -0.28887695657697543 HIISATSLSTS(ph)PTELGSR ddPTM_PC-9_Lapatinib_30min_R1 3 HIISATSLSTSPTELGSR 18 0 Q5JSZ5;Q5JSZ5-5;A0A1W2PQP5 Q5JSZ5 PRRC2B Protein PRRC2B 1 HIISATS(0.002)LS(0.011)T(0.199)S(0.708)PT(0.08)ELGSR;HIISATSLS(0.001)T(0.227)S(0.771)PTELGSR;HIISATS(0.006)LS(0.019)T(0.22)S(0.753)PT(0.002)ELGSR 281.49 1.8957999999999996e-92 79607200.0 106960.0 80689.0 139275.0 94714.0 124310.0 122164.0 100282.0 95034.0 130923.0 86617.0 True False 105434.73078593827 80502.16957801729 127824.34711704717 101679.58351664187 116998.33020286319 116939.33049819313 105474.11127640556 99449.62657867363 116177.07305969033 101588.63304010223 1.0378595284800987 0.7924328457716225 1.2582544256362655 1.0008952820194337 1.1516872183591442 1.1511064476281632 1.03824717510245 0.9789444311098839 1.1436030743107775 1.0 16.632379459478955 -5.25187761507175 24.999171889893137 1.0888962421704744 0.9151462073171853 0.32948489951233095 0.09995321278682844 742.1777177851606 1940408.353980583 0.02411600532880392 0.06211220048672216 5.599153643730582e-06 5.25187761507175 -0.1737500348532891 HIKEEPLS(ph)EEEPCT(ph)STAIASPEKK ddPTM_PC-9_Lapatinib_30min_R1 1 HIKEEPLSEEEPCTSTAIASPEKK 24 2 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 2 HIKEEPLS(0.978)EEEPCT(0.328)S(0.328)T(0.328)AIAS(0.037)PEKK 60.735 0.025117 6905800.0 32042.0 37086.0 30030.0 38514.0 37874.0 30739.0 31115.0 30680.0 30387.0 30182.0 True False 31585.075204216868 37000.12964555707 27561.049319152244 41346.44803893769 35646.32578314893 29424.364626108825 32725.98245313574 32105.504802846477 26964.496070704237 35398.918485012975 0.8922610225391266 1.045233335623573 0.7785845019762654 1.1680144424876358 1.0069891202535102 0.8312221357431124 0.9244910255377183 0.9069628727905671 0.761732200437715 1.0 15.111417663017512 -6.752652644720369 24.99659480757668 0.8815424100174328 0.9813933170181932 0.15079916181266506 0.11047340641046886 356.4760311766458 1014104.9695931195 0.035868000941400524 0.03535010374755349 1.7674508894041435e-07 6.752652644720369 0.09985090700076038 HIKEEPLS(ph)EEEPCTSTAIAS(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 3 HIKEEPLSEEEPCTSTAIASPEK 23 1 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 2 HIKEEPLS(0.752)EEEPCT(0.129)S(0.15)T(0.144)AIAS(0.825)PEK;HIKEEPLS(0.999)EEEPCT(0.001)S(0.003)T(0.013)AIAS(0.984)PEK;HIKEEPLS(0.99)EEEPCT(0.013)S(0.013)T(0.015)AIAS(0.968)PEK 62.255 0.0015755 54484100.0 124795.0 122672.0 113924.0 128965.0 132243.0 124771.0 141332.0 125673.0 119459.0 144070.0 True False 164477.21410274637 162323.3250182931 112413.29332338086 99234.1117393878 113883.34213033918 116969.04964582874 153910.27420363715 106253.12552824563 125773.35885961789 139026.15315149527 1.183066713523443 1.1675740235825354 0.8085765935052905 0.7137801736573512 0.8191504947003875 0.8413456532769691 1.107059864023734 0.7642671764963731 0.9046740919499084 1.0 17.084996778053394 -5.254371776878203 24.06387730113313 0.8615059088995456 1.175320457545615 0.5581550807028175 0.10850855407763318 234.75480337399412 799286.8604132967 0.028525105586926273 0.07193714837394134 5.567089753425756e-06 5.254371776878203 0.3138145486460695 HIKEEPLS(ph)EEEPCTSTAIAS(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 2 HIKEEPLSEEEPCTSTAIASPEK 23 1 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 2 HIKEEPLS(0.971)EEEPCT(0.043)S(0.042)T(0.034)AIAS(0.909)PEK;HIKEEPLS(0.995)EEEPCT(0.073)S(0.057)T(0.168)AIAS(0.707)PEK 50.261 0.013978 127690000.0 118380.0 141871.0 133279.0 147702.0 132329.0 128792.0 141720.0 131900.0 125944.0 123187.0 True False 116691.87949176671 141542.506416028 122321.31509181765 158564.49779942815 124545.66838882388 123283.86638881582 149057.56815871442 138028.55552462357 111758.86047088483 144479.70881364009 0.8076696752087448 0.9796704850685939 0.8466331784319703 1.0974862774948944 0.8620287887586449 0.8532953686101061 1.0316851368449196 0.9553490705235456 0.773526340747538 1.0 17.140507364744046 -4.747520383101773 24.672623396129033 0.9326719270791053 0.8076693040257724 0.13861578662619023 0.09393862590831688 1254.1542616336276 2222944.847312855 0.02251719587490506 0.4463080301241056 1.7884615877924523e-05 4.747520383101773 -0.12500262305333287 HIKEEPLS(ph)EEEPCTSTAIASPEK ddPTM_PC-9_AZD4547_30min_R2 4 HIKEEPLSEEEPCTSTAIASPEK 23 1 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 1 HIKEEPLS(0.936)EEEPCT(0.037)S(0.013)T(0.013)AIASPEK;HIKEEPLS(0.996)EEEPCT(0.001)S(0.001)T(0.001)AIASPEK;HIKEEPLS(0.936)EEEPCT(0.034)S(0.023)T(0.007)AIASPEK;HIKEEPLS(0.493)EEEPCT(0.309)S(0.087)T(0.111)AIAS(0.001)PEK 70.767 0.00044857 194738700.0 228868.0 286157.0 279621.0 393242.0 325127.0 348638.0 247165.0 325930.0 276170.0 303653.0 True False 301643.2632498688 378651.6541448715 275913.0428388843 302586.1324283356 279988.7281505317 326837.6107462669 269162.2061779492 275565.007626309 290767.7823877703 293022.2008947793 1.029421191734838 1.2922285512449643 0.941611393253992 1.0326389314678261 0.9555205281222778 1.1154022109868402 0.9185727407548961 0.9404236497604529 0.9923063218414002 1.0 18.16065044934858 -5.280212630659318 24.995561254520094 0.9875709023651023 1.1608248944847797 0.4332065842834161 0.07950211468126632 613.027219057435 816211.894992492 0.019636759905660675 0.04099296103778734 5.24550577309478e-06 5.280212630659318 0.1732539921196774 HIKEEPLS(ph)EEEPCTSTAIASPEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 HIKEEPLSEEEPCTSTAIASPEK 23 1 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 1 HIKEEPLS(0.993)EEEPCT(0.002)S(0.002)T(0.003)AIASPEK;HIKEEPLS(0.877)EEEPCT(0.036)S(0.042)T(0.042)AIAS(0.003)PEK;HIKEEPLS(0.837)EEEPCT(0.05)S(0.05)T(0.059)AIAS(0.004)PEK;HIKEEPLS(0.999)EEEPCTSTAIASPEK;HIKEEPLS(0.551)EEEPCT(0.149)S(0.149)T(0.149)AIAS(0.002)PEK;HIKEEPLS(1)EEEPCTSTAIASPEK 84.602 1.686e-05 181683000.0 416356.0 437450.0 374532.0 489089.0 529915.0 383412.0 486348.0 362749.0 362982.0 357651.0 True False 486836.8473941577 480877.14499366557 383462.2633005196 461686.92897793185 426081.9597766558 363305.1997617494 440277.5965853998 353227.2231143358 368289.9250555215 422490.295136241 1.1523030303859803 1.138196901868708 0.9076238382632292 1.0927752289056747 1.0085011766702394 0.8599137162300826 1.0421010888390299 0.8360599691418478 0.8717121536170637 1.0 18.68855867661359 -3.6809504609374275 0.4076029853508758 0.9123623417943535 1.7125858422705431 0.45702503433255115 0.08185991876108478 11.691203166891992 0.7605106782656705 0.06066688451130451 5.473643694764381 0.0002084728670171164 3.6809504609374275 0.8002235004761896 HIKEEPLS(ph)EEEPCTSTAIASPEK ddPTM_PC-9_Lapatinib_30min_R1 5 HIKEEPLSEEEPCTSTAIASPEK 23 1 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 1 HIKEEPLS(0.998)EEEPCTS(0.001)T(0.001)AIASPEK;HIKEEPLS(0.996)EEEPCT(0.002)S(0.001)T(0.001)AIASPEK;HIKEEPLS(0.999)EEEPCTSTAIASPEK;HIKEEPLS(0.999)EEEPCT(0.001)STAIASPEK;HIKEEPLS(0.999)EEEPCTSTAIASPEK 83.31 2.9821999999999997e-05 193449000.0 289077.0 344375.0 411624.0 315604.0 336926.0 402261.0 386606.0 439408.0 393064.0 297342.0 True False 284954.7089697713 343577.6208458369 377781.86363458866 338814.5709840803 317108.6751020022 385057.23474619037 406622.5670023135 459824.49981776974 348792.99317258364 348737.1685166901 0.8171044978709625 0.9852050537291488 1.0832853442076065 0.9715470605705314 0.9093056425582174 1.104147390953431 1.1659857443123476 1.3185417022612638 1.000160076587566 1.0 18.411780609635557 -6.888103249491787 5.1440695101035585 1.1459818028923907 0.963886963289802 0.364972296362543 0.10598448232432277 0.21875685054837224 9.007038081665096 0.03786461286406528 0.03335081547313715 1.2938881949435985e-07 6.888103249491787 -0.18209483960258877 HIKEEPLS(ph)EEEPCTSTAIASPEKK ddPTM_PC-9_AZD4547_30min_R2 4 HIKEEPLSEEEPCTSTAIASPEKK 24 2 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 1 HIKEEPLS(0.932)EEEPCT(0.049)S(0.009)T(0.009)AIASPEKK;HIKEEPLS(0.561)EEEPCT(0.197)S(0.197)T(0.044)AIASPEKK;HIKEEPLS(0.999)EEEPCT(0.001)STAIASPEKK;HIKEEPLS(0.989)EEEPCT(0.01)S(0.001)TAIASPEKK 76.015 8.2451e-05 71296000.0 266441.0 297988.0 352088.0 480582.0 382938.0 415176.0 300720.0 390770.0 315159.0 353589.0 True False 351163.6956829188 394306.79352705635 347419.08306978736 369791.24481788406 329773.6686910306 389214.9790877408 327483.49742816715 330385.4755012818 331817.6613301496 341209.9567341161 1.029171888898187 1.1556133862597548 1.01819737734239 1.0837645195273116 0.9664831350393532 1.1406905672187992 0.9597712228642697 0.9682761859107496 0.9724735599926081 1.0 18.380300220510797 -7.291682107977453 24.961054710719814 0.9724865731708073 1.063900965370416 0.40838000187427914 0.05331410062419294 676.6788370037408 558498.8833558933 0.02125132495551568 0.014329326605378123 5.108788128663054e-08 7.291682107977453 0.09141439219960856 HIKEEPLS(ph)EEEPCTSTAIASPEKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HIKEEPLSEEEPCTSTAIASPEKK 24 2 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 1 HIKEEPLS(0.995)EEEPCT(0.005)STAIASPEKK;HIKEEPLS(0.998)EEEPCT(0.002)STAIASPEKK;HIKEEPLS(0.925)EEEPCT(0.071)S(0.003)T(0.001)AIASPEKK 103.31 6.5582e-07 36477400.0 169229.0 153158.0 145648.0 219282.0 222311.0 195997.0 213244.0 158740.0 170303.0 169695.0 True False 197876.12727489445 168362.51405404077 149120.80069311557 206996.340461836 178750.75542286676 185718.5722870008 193043.98456713514 154573.24319893244 172793.35919337795 200459.360195119 0.9871134332778967 0.8398835249706651 0.7438954237306128 1.0326100026476897 0.8917057065775229 0.9264649558206207 0.9630080849267102 0.771095163870009 0.861986983422415 1.0 17.612950258310136 -11.034258225647102 2.932843434332684 1.0040814638713897 0.8888809616948815 0.12434593305674324 0.08674177641158276 86690893.10816301 99812712.54303017 2859788.091266973 0.021358920932535854 9.241485242870406e-12 11.034258225647102 -0.11520050217650823 HIKEEPLS(ph)EEEPCTSTAIASPEKK ddPTM_PC-9_Lapatinib_30min_R1 2 HIKEEPLSEEEPCTSTAIASPEKK 24 2 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 1 HIKEEPLS(0.944)EEEPCT(0.053)S(0.003)TAIASPEKK;HIKEEPLS(0.991)EEEPCT(0.006)S(0.001)T(0.001)AIASPEKK 81.574 2.9996e-05 30962000.0 135002.0 116101.0 129293.0 92945.0 116703.0 142777.0 124421.0 122285.0 135347.0 85491.0 True False 133076.84672366505 115832.17526772409 118663.02862541279 99780.4853554307 109838.75898692598 136670.76053944294 130862.91058337154 127966.8075233402 120102.795592905 100268.00544040323 1.3272114682959617 1.1552256849925255 1.1834585529473118 0.9951378300303152 1.0954517196635707 1.3630545450580105 1.3051312829908954 1.2762476620660461 1.1978177392218206 1.0 16.613501803656767 -6.737438859413901 24.99995283592331 1.2505083760810625 1.1446265479052096 0.07949811067536672 0.11898158436429153 448.88316886420927 467574.27811017924 0.03933818010320441 0.03931769169163929 1.8304637834305343e-07 6.737438859413901 -0.1058818281758529 HIKEEPLSEEEPCT(ph)STAIASPEKK ddPTM_PC-9_Lapatinib_30min_R1 2 HIKEEPLSEEEPCTSTAIASPEKK 24 2 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 1 HIKEEPLS(0.203)EEEPCT(0.625)S(0.161)T(0.011)AIASPEKK;HIKEEPLS(0.108)EEEPCT(0.819)S(0.072)T(0.002)AIASPEKK 70.12100000000001 0.00036163 53226000.0 87929.0 93293.0 84163.0 65709.0 97310.0 97524.0 91111.0 92487.0 91461.0 71921.0 True False 86675.11633579645 93076.9857904048 77243.44301857527 70541.4590587983 91586.41711882083 93353.12585954762 95828.28177045305 96784.28366039344 81159.69905297268 84352.44902129119 1.0275352682874566 1.1034295609711517 0.9157225891459114 0.8362704328951149 1.085758839031499 1.1067032071112077 1.136046230812638 1.147379652675696 0.9621498841425145 1.0 16.364142334720043 -6.417401562520212 21.845241896041525 1.0852658558583943 0.9743743076968696 0.2529214313567383 0.084450738604955 16.491333799723826 3402.740519486754 0.02763967245961997 0.0313404039749789 3.82470934953852e-07 6.417401562520212 -0.11089154816152469 HIKEEPLSEEEPCTST(ph)AIASPEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HIKEEPLSEEEPCTSTAIASPEK 23 1 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 1 HIKEEPLS(0.167)EEEPCT(0.202)S(0.268)T(0.36)AIAS(0.002)PEK 63.869 0.0015692 16613000.0 84108.0 90864.0 68709.0 106390.0 103730.0 80522.0 87264.0 64313.0 64132.0 76183.0 True False 98345.82319127822 99884.37742074413 70347.28314033366 100429.31322103363 83404.85113203558 76299.28456912035 78997.7221833509 62624.85189525612 65069.809174176 89994.37483570367 1.092799670766325 1.1098957862988208 0.7816853360975249 1.1159510069866065 0.926778493481419 0.8478228190196836 0.8778073332646782 0.6958751811942231 0.723043071224944 1.0 16.4575472071 -6.758260073505113 1.3938330172070188 0.7941365283487479 1.0198570241798823 0.3601152021313354 0.12020957362556267 0.4349193932463996 1.7655056692767617 0.055661178145857755 0.05045069868522382 1.744776995353306e-07 6.758260073505113 0.2257204958311344 HILANFK ddPTM_PC-9_AZD4547_30min_R2 1 HILANFK 7 0 Q5W0H4;A0A0B4J2C3;P13693;J3KPG2;E9PJF7;P13693-2;H0YCX0;Q56UQ5 Q5W0H4 TPT1 Translationally-controlled tumor protein;TPT1-like protein 0 88.734 0.014328 1895500.0 27957.0 26424.0 38713.0 46503.0 36767.0 32628.0 35305.0 38671.0 29865.0 41797.0 False True 36846.744458275476 34965.041250516624 38199.640325375156 35782.45181418798 31662.53669461662 30587.76600206861 38447.07660515246 32695.28552117622 31443.602929394114 40333.69975201666 0.9135473483667503 0.8668939736620217 0.9470899163785538 0.8871601671601892 0.7850144392725469 0.7583674741005935 0.9532246444421486 0.8106195494635098 0.7795863787036287 1.0 15.299698127695263 -6.016558634830712 23.36224663188471 0.8388556136237652 0.9069781525682273 0.11617992967223667 0.07482911732248215 579.5700642058144 817707.3353693392 0.02133924793143038 0.028367522270280502 9.625900432940463e-07 6.016558634830712 0.06812253894446219 HILANFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HILANFK 7 0 Q5W0H4;A0A0B4J2C3;P13693;J3KPG2;E9PJF7;P13693-2;H0YCX0;Q56UQ5 Q5W0H4 TPT1 Translationally-controlled tumor protein;TPT1-like protein 0 ; 106.76 0.008399 5294500.0 65413.0 71008.0 72875.0 80517.0 96132.0 74629.0 81671.0 93172.0 66874.0 61139.0 False True 76486.12893435916 78057.20496447656 74612.61637997656 76005.89352963596 77295.62468933615 70715.32386315397 73934.53163316453 90726.33372389438 67851.90573682175 72223.01672394233 1.0590270581843972 1.0807801792998237 1.033086400491522 1.0523777180362446 1.0702353376456542 0.979124482344026 1.0236976380502647 1.2561969554758032 0.9394775905882157 1.0 16.140171061837872 HILANFK ddPTM_PC-9_Lapatinib_30min_R1 2 HILANFK 7 0 Q5W0H4;A0A0B4J2C3;P13693;J3KPG2;E9PJF7;P13693-2;H0YCX0;Q56UQ5 Q5W0H4 TPT1 Translationally-controlled tumor protein;TPT1-like protein 0 ; 111.69 0.0014398 2624100.0 55215.0 62468.0 69085.0 66598.0 70814.0 63557.0 56563.0 65620.0 72203.0 64656.0 False True 54427.62397480909 62323.359184022476 63405.09797581192 71495.83908441514 66648.85974568062 60838.81526860332 59491.55537511543 68668.94475758758 64070.73780870303 75831.70345129535 0.7177423359580267 0.821864159019599 0.8361291529806566 0.9428225376782546 0.8789049528405671 0.802287334975647 0.7845208885927935 0.9055440090659678 0.8449070097687299 1.0 16.21051351092145 -14.522878745280206 0.16163745058126702 1.5847205069593118 0.7995440092588405 0.43846164043636227 0.05803643952018857 144.63086050080827 1.3311482467000504 27.213635904636373 0.2586135353868542 3.000000000000909e-15 14.522878745280206 -0.7851764977004713 HIMGQNVADYMR ddPTM_PC-9_AZD4547_30min_R2 1 HIMGQNVADYMR 12 0 P46777;A0A2R8Y6J3 P46777 RPL5 60S ribosomal protein L5 0 74.392 0.019184 0.0 11765.0 9356.2 9051.9 12702.0 9734.5 9283.9 9803.3 10393.0 9860.8 11298.0 False True 15506.025272797902 12380.40867953692 8931.865891593612 9773.750143943742 8383.0327047011 8703.37626537345 10675.774708491468 8787.000657381106 10382.021756777807 10902.460458843565 1.4222500811933825 1.1355609796772537 0.8192523077988787 0.8964719643643132 0.7689120026022361 0.7982946875366724 0.9792078355883217 0.8059649187036035 0.9522641055172457 1.0 13.41236613759715 -4.946849000085206 2.436945270946319 0.8678774156035018 1.4593214128901013 0.8271482407992528 0.0785229869968444 0.1383678168083125 1.3323746566531898 0.020141926147028952 0.1497014007993681 1.1301888018846071e-05 4.946849000085206 0.5914439972865995 HIMGQNVADYMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HIMGQNVADYMR 12 0 P46777;A0A2R8Y6J3 P46777 RPL5 60S ribosomal protein L5 0 71.153 0.016149 5399700.0 38713.0 33242.0 24056.0 42895.0 54976.0 41930.0 42911.0 47555.0 34571.0 35693.0 False True 45266.346283396895 36542.046071275494 24629.58627288805 40491.73221746634 44203.847448518085 39731.11698645362 38846.15943126349 46306.73163868745 35076.53547309359 42163.85835436744 1.0735816893927141 0.8666675085604536 0.5841397641052661 0.9603421934765158 1.0483824102862098 0.9423026861662477 0.9213141526275834 1.0982565032237113 0.8319100016486103 1.0 15.36371927152496 -5.964685516534606 24.99991212864859 0.9771410365382099 0.832026338897179 0.17550518395244652 0.12910692425597065 283.23761398321903 200508.52965071422 0.03648865211417891 0.054121202615035134 1.0847120967830424e-06 5.964685516534606 -0.1451146976410309 HIMGQNVADYMR ddPTM_PC-9_Lapatinib_30min_R1 1 HIMGQNVADYMR 12 0 P46777;A0A2R8Y6J3 P46777 RPL5 60S ribosomal protein L5 0 74.237 0.014286000000000002 4596500.0 16086.0 14016.0 14757.0 15382.0 11312.0 15664.0 13643.0 10969.0 17020.0 12255.0 False True 15856.61069018888 13983.546813140476 13543.73642366732 16513.24359284777 10646.650400247689 14994.087234567436 14349.367784288319 11478.659784303229 15103.028371454444 14373.26042123895 1.1032020728406218 0.9728862069789951 0.9422869986864033 1.1488864119129596 0.7407261879507478 1.0431931792184819 0.9983377023549002 0.7986121066408527 1.0507726103074801 1.0 13.811099738492196 -1.522880488993658 0.9477082559060487 0.9545903654614019 98.4453398508031 0.10903525021174665 0.1136876198984519 2690.8701030270345 4.723868432230516 0.03579812543466531 568641.5800198519 0.029999879548792865 1.522880488993658 97.4907494853417 HITIFSPEGR ddPTM_PC-9_AZD4547_30min_R2 2 HITIFSPEGR 10 0 G3V3U4;G3V3I1;G3V295;G3V5Z7;P60900;G3V4S5;G3V2S7 G3V3U4 PSMA6 Proteasome subunit alpha type;Proteasome subunit alpha type-6 0 ; 97.47200000000001 0.0052949 5344500.0 25045.6 30063.0 63316.0 96605.0 75024.0 63692.0 43008.0 70543.0 51463.0 69937.0 False True 33009.579819157414 39780.27683599306 62476.388470060505 74334.20978237173 64608.212608505324 59709.32917137901 46835.62868246415 59642.20026687526 54183.22911620323 67488.52691716593 0.48911394761472143 0.5894376222616117 0.9257334738798311 1.101434764958021 0.9573214227627779 0.8847330338779663 0.6939791224062316 0.8837383625231428 0.8028509672867307 1.0 16.042354643689713 -5.183931066770799 4.124101613481061 0.9028143603560577 0.5151859170757669 0.6677862260093261 0.10423842081177888 0.14455967366724218 4.611302825273844 0.029967319946946853 0.08812743723952879 6.547400891958772e-06 5.183931066770799 -0.3876284432802908 HITIFSPEGR ddPTM_PC-9_Lapatinib_30min_R1 1 HITIFSPEGR 10 0 G3V3U4;G3V3I1;G3V295;G3V5Z7;P60900;G3V4S5;G3V2S7 G3V3U4 PSMA6 Proteasome subunit alpha type;Proteasome subunit alpha type-6 0 107.55 0.0018089000000000002 3553500.0 22792.0 22097.0 41914.0 25551.0 27952.0 40671.0 26880.0 25141.0 36902.0 23039.0 False True 22466.9819004591 22045.835754135624 38467.992712718835 27430.10577563732 26307.91831574641 38931.596138731635 28271.714875149897 26309.14264173284 32745.70816471282 27021.260452462182 0.8314557324216867 0.8158699995849676 1.423619478461954 1.0151305052513893 0.9736007083026073 1.4407764658951792 1.0462766873842768 0.9736460180315366 1.2118497663098107 1.0 14.721807352736493 -5.2061999585818 24.85231366609029 1.1322904302059085 0.8236621391438813 0.3609851306214942 0.16597092511956152 302.6594511748324 136165.64375329387 0.04143976647268395 0.10963921306873084 6.22013830595276e-06 5.2061999585818 -0.30862829106202716 HIYDTK ddPTM_PC-9_AZD4547_30min_R2 2 HIYDTK 6 0 A0A087X1X5;B4DDF4;B4DUT8;Q99439-2;Q99439 A0A087X1X5 CNN2 Calponin;Calponin-2 0 ; 122.15 0.00014816 1519900.0 28402.0 26360.0 32616.0 46951.0 42704.0 41140.0 33322.0 37252.0 38496.0 44303.0 False True 37433.24520170045 34880.35450210485 32183.49052908417 36127.17233571896 36775.286724696285 38567.50929646628 36287.593446732506 31495.559365800153 40530.819968858355 42751.96545478369 0.875591210918512 0.8158772147913481 0.7527955776237424 0.8450412034021829 0.860201076921046 0.9021224845734153 0.8487935714934982 0.7367043603904294 0.9480457690705586 1.0 15.383703126721985 -8.46870713271997 6.591273022254618 0.9998261981255804 0.8314495131379043 0.5939701839649495 0.04866937317261122 0.13810613845378264 12.805659939350416 0.048945370812011404 0.012672072095302961 3.39854376755313e-09 8.46870713271997 -0.1683766849876761 HIYDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HIYDTK 6 0 A0A087X1X5;B4DDF4;B4DUT8;Q99439-2;Q99439 A0A087X1X5 CNN2 Calponin;Calponin-2 0 ; 121.68 0.013973 4690900.0 77058.0 83366.0 84572.0 103248.0 104001.0 92290.0 96185.0 96049.0 89599.0 77334.0 False True 90102.39743512527 91642.02553330001 86588.51722109628 97463.3492945323 83622.75062742522 87450.1499327403 87073.6604809043 93527.81552232761 90909.21587034564 91354.04202439278 0.9862989686987982 1.0031523893472643 0.9478345489953904 1.0668750625014298 0.9153700129119279 0.9572663452525715 0.9531451324031667 1.0237950445296597 0.9951307446918619 1.0 16.479180942879907 -7.76864391108062 24.998881653973314 1.0070971677831286 0.9761663741747822 0.11630566144150656 0.03862310970637189 392.97937619072655 1363565.9584218608 0.02047352781288983 0.010160019046252383 1.7035547230913277e-08 7.76864391108062 -0.030930793608346385 HIYDTK ddPTM_PC-9_Lapatinib_30min_R1 1 HIYDTK 6 0 A0A087X1X5;B4DDF4;B4DUT8;Q99439-2;Q99439 A0A087X1X5 CNN2 Calponin;Calponin-2 0 142.63 0.00118 2701400.0 45905.0 35940.0 39735.0 37967.0 41929.0 41043.0 34962.0 37372.0 40770.0 35652.0 False True 45250.386282053994 35856.783138147 36468.14168153562 40759.21983419914 39462.8186555857 39287.686565906 36772.16128962018 39108.439553193566 36178.053272867095 41814.400696696124 1.0821723025586578 0.8575223497339315 0.8721431151449475 0.9747651324683374 0.9437614314224471 0.9395731114474691 0.8794138066535927 0.9352863822411219 0.8652055911380221 1.0 15.351712265294564 HIYYITGETK ddPTM_PC-9_AZD4547_30min_R2 2 HIYYITGETK 10 0 P07900;P07900-2;Q58FG0 P07900 HSP90AA1;HSP90AA5P Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-alpha A5 0 ; 120.45 0.00059153 95382000.0 313120.0 259050.0 383940.0 477910.0 460270.0 419040.0 349960.0 419680.0 339130.0 399040.0 False True 412685.646699403 342782.84650114796 378848.70473806094 367735.23313589615 396369.45533851534 392837.3625569086 381105.76203764824 354828.0992869917 357055.71945238305 385069.7310583231 1.0717166617204124 0.8901838260801384 0.9838444161706391 0.9549834834465307 1.029344618308835 1.0201720126825784 0.9897058410439576 0.9214645314026227 0.927249510033036 1.0 18.554760196978798 -7.743980524850678 24.371372899933544 0.9432677718999408 0.9883992800645695 0.12545080785444718 0.049359569923133555 334.65419977674424 467155.85208965436 0.022968267099234788 0.01321786751438309 1.803098595736895e-08 7.743980524850678 0.04513150816462863 HIYYITGETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HIYYITGETK 10 0 P07900;P07900-2;Q58FG0 P07900 HSP90AA1;HSP90AA5P Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-alpha A5 0 ; 131.12 0.00015988 73597000.0 501220.0 467550.0 498390.0 600850.0 636590.0 586300.0 653510.0 605210.0 508410.0 418280.0 False True 586066.6464537544 513965.2740696968 510273.50775460165 567186.3224819816 511854.75929955125 555553.3958778373 591604.8017973247 589323.8787730009 515844.53443277767 494110.85289734113 1.1861035697095252 1.040182119166042 1.0327105846036102 1.1478928648422604 1.0359107805427958 1.124349713470596 1.1973118953536512 1.1926956781405522 1.0439854364825134 1.0 18.91447521864405 -6.965533677818029 24.897468250026712 1.1297383574317423 1.085472264988324 0.0 0.07350492217647986 484.44980126903823 349950.9374736454 0.0252838272522947 0.022298161139863992 1.0825957608561023e-07 6.965533677818029 -0.04426609244341839 HIYYITGETK ddPTM_PC-9_Lapatinib_30min_R1 2 HIYYITGETK 10 0 P07900;P07900-2;Q58FG0 P07900 HSP90AA1;HSP90AA5P Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-alpha A5 0 ; 147.95 0.00012538 106732000.0 683450.0 624330.0 658820.0 578960.0 604860.0 564730.0 556520.0 562910.0 572320.0 534260.0 False True 673703.8776706186 622884.4022437218 604654.3627187448 621538.6497539442 569283.3240005143 540577.8143499277 585333.8825267273 589064.8536039863 507859.29480322043 626606.1291432994 1.0751632426444848 0.9940605003263118 0.9649672012392103 0.99191281547743 0.9085186012764395 0.8627075114777599 0.9341336691471565 0.9400879215933623 0.8104920638066044 1.0 19.257199355925856 -4.681363584499349 0.6155431975487943 0.9047917372077859 1.1884068980701368 0.49432611976028173 0.050887064363305715 3.3012132873478364 0.8686875969944158 0.024499873796854556 0.6834414757937309 2.0827465104468874e-05 4.681363584499349 0.28361516086235083 HKDTYSTEAPLGEGTEQYVNSIS(ph)D ddPTM_PC-9_AZD4547_30min_R2 2 HKDTYSTEAPLGEGTEQYVNSISD 24 1 Q9GZR1-2;Q9GZR1 Q9GZR1-2 SENP6 Sentrin-specific protease 6 1 HKDTYSTEAPLGEGTEQYVNS(0.162)IS(0.838)D;HKDTYSTEAPLGEGTEQYVNS(0.042)IS(0.957)D 112.86 1.6944e-06 4092400.0 14729.7 14598.4 24442.0 31429.0 22618.7 23231.0 17636.5 30175.0 18740.7 23009.0 True False 19413.438203207068 19317.047312728642 24117.88310988089 24183.529623209542 19478.483932181698 21778.36189757436 19206.114333572343 25512.14710251849 19731.295142102663 22203.46191339454 0.8743428515305375 0.8700015965111896 1.0862217434359391 1.0891783325293294 0.8772723824851402 0.9808543362526844 0.8650053945860574 1.1490166354251243 0.8886584992495917 1.0 14.43849701539968 -5.2235939861508855 23.4934155832878 0.9917838961186808 0.87217201350707 0.2165656564461227 0.09118290856105998 418.9646643699663 260078.89056760288 0.02281893010641204 0.060368672768625176 5.975937047769412e-06 5.2235939861508855 -0.11961188261161082 HKLDVTSVEDYK ddPTM_PC-9_Lapatinib_30min_R1 1 HKLDVTSVEDYK 12 1 E7ENZ3;B7ZAR1;E9PCA1;P48643-2;P48643 E7ENZ3 CCT5 T-complex protein 1 subunit epsilon 0 80.834 0.0062456000000000005 5525000.0 91683.0 67858.0 95696.0 77937.0 93473.0 84761.0 80982.0 77050.0 86568.0 79221.0 False True 90375.58360739707 67700.87897018321 87828.24427724261 83668.74697021057 87975.10191498869 81135.96961754146 85174.85171203077 80630.02428485392 76817.8002385469 92914.24429465292 0.9726773789473533 0.7286383211113229 0.9452613530248236 0.9004942956311123 0.9468419248613694 0.8732349946283825 0.9167039172370738 0.8677897011050012 0.8267602112216464 1.0 16.503612166662712 -11.935443353197728 2.277456123401139 1.994711446742875 0.8857109077123339 0.206094703044162 0.06682016311639444 14652524.515378844 2322726.6214105617 74282571.84428543 0.016585997146415916 1.1602635441894896e-12 11.935443353197728 -1.109000539030541 HKMS(ph)PPPSGFGER ddPTM_PC-9_AZD4547_30min_R2 1 HKMSPPPSGFGER 13 1 A0A087WZ13;Q8IY67-2;E9PAU2;K7EQG2 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 HKMS(1)PPPSGFGER 52.254 0.044347000000000004 14104000.0 10888.0 9928.6 15067.0 24676.0 15720.0 18891.0 13054.0 17141.0 18640.0 14004.0 True False 14350.157515531106 13137.825785644838 14867.201735397093 18987.3294403996 13537.549346951691 17709.74278365447 14215.780711051135 14492.252310994842 19625.2723456858 13513.724222485864 1.0618950985882543 0.9721839493945305 1.1001557742801307 1.4050404705466797 1.0017630317204627 1.3105005320581231 1.0519513701039644 1.072409949500137 1.4522475094638057 1.0 13.72213769869027 -5.5243721686994585 24.996884021195342 1.185521523554821 1.0218220716470623 0.16139830602735428 0.15422110620293958 78.23253420894888 1309450.7198292688 0.03963688465835916 0.06930333943910842 2.9897015135214083e-06 5.5243721686994585 -0.1636994519077588 HKMS(ph)PPPSGFGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HKMSPPPSGFGER 13 1 A0A087WZ13;Q8IY67-2;E9PAU2;K7EQG2 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 HKMS(0.999)PPPS(0.001)GFGER 54.023 0.039391 15414000.0 9153.6 7363.3 6828.3 9882.9 13436.0 11467.0 11110.0 10512.0 11420.0 5800.7 True False 10703.12368815906 8094.279761645598 6991.112568471959 9329.193153794111 10803.312251133022 10865.650333500194 10057.580370565523 10236.071138384661 11586.9958954826 6852.320991684063 1.561970564593852 1.1812464377352971 1.0202546811447293 1.3614647015392252 1.576591678096204 1.5856890456075663 1.4677625847900797 1.4938108052449814 1.6909592982501127 1.0 12.7423770196018 -6.001566205632606 24.980930474967995 1.4968072438651312 1.2377817236357334 0.16181636536932242 0.2133642933199371 86.30860094697952 1376679.9395375154 0.058021028545659215 0.08469170332903186 9.96400173226059e-07 6.001566205632606 -0.25902552022939784 HKMS(ph)PPPSGFGER ddPTM_PC-9_Lapatinib_30min_R1 3 HKMSPPPSGFGER 13 1 A0A087WZ13;Q8IY67-2;E9PAU2;K7EQG2 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 HKMS(1)PPPSGFGER;HKMS(1)PPPSGFGER;HKMS(0.998)PPPS(0.002)GFGER 69.03 0.014878 53986000.0 55088.0 47231.0 50796.0 52007.2 54209.7 54034.0 54070.0 56624.0 53959.0 41391.7 True False 54302.435018098084 47121.639521364006 46619.748958230346 55831.98297893334 51021.19202637085 51723.09177940608 56869.480033458145 59254.957756075 47881.569206539956 48546.20019402662 1.118572304342364 0.9706555679544637 0.9603171570978419 1.150079362664582 1.050982194743406 1.065440581810363 1.1714506965769829 1.220588996033639 0.9863093097949931 1.0 15.567070757052404 -5.7627254325426 24.999999896029962 1.1017923279271538 1.0119290675154182 0.14865547305386906 0.08039763026128047 54.52187230668753 1059910.1282033208 0.02226209312680235 0.035198175878968875 1.726929337457636e-06 5.7627254325426 -0.08986326041173553 HKS(ph)DNETNLQQQVVWGNR ddPTM_PC-9_AZD4547_30min_R2 1 HKSDNETNLQQQVVWGNR 18 1 A0A0U1RR27;Q7Z401;Q7Z401-2 A0A0U1RR27 DENND4A C-myc promoter-binding protein 1 HKS(1)DNETNLQQQVVWGNR 116.87 0.00025943 0.0 16928.0 12942.0 19895.0 19279.0 20793.0 18612.0 16931.0 18215.0 17816.0 18441.0 True False 22310.751875726557 17125.24840539609 19631.17930083792 14834.524407580802 17906.250863305766 17448.188697759615 18437.826200306947 15400.290289059629 18757.717387915123 17795.38620300356 1.2537379982211838 0.9623420481037741 1.1031611832916843 0.8336163227003742 1.0062299665226424 0.9804894650060844 1.036101492261795 0.8654091635538834 1.0540775667318272 1.0 14.119215622715325 HKS(ph)DNETNLQQQVVWGNR ddPTM_PC-9_Lapatinib_30min_R1 3 HKSDNETNLQQQVVWGNR 18 1 A0A0U1RR27;Q7Z401;Q7Z401-2 A0A0U1RR27 DENND4A C-myc promoter-binding protein 1 HKS(0.974)DNET(0.026)NLQQQVVWGNR;HKS(1)DNETNLQQQVVWGNR;HKS(0.766)DNET(0.234)NLQQQVVWGNR 116.87 5.4667e-05 26929200.0 54166.0 51949.0 48510.0 46392.0 56375.0 66295.0 49256.0 63960.0 54579.0 43575.7 True False 53393.58290717213 51828.71528223705 44521.69505401514 49803.822439175245 53059.1333375144 63459.7173911931 51806.23466854103 66931.81509745964 48431.73827765056 51107.701684029525 1.044726746611987 1.0141077288637463 0.8711347524345352 0.9744876172887711 1.0381827315489454 1.2416859944814036 1.0136678614278165 1.3096228727181236 0.9476407015341258 1.0 15.641253094276204 -6.527361698496348 24.86803081414096 1.1189451103653179 0.9757051974236676 0.2174171164059302 0.11098421587695936 154.37237537373386 856330.3645879513 0.03444560326694894 0.03457466150167315 2.9691921350719564e-07 6.527361698496348 -0.14323991294165028 HLAESESLLT(ph)SPPK ddPTM_PC-9_AZD4547_30min_R2 2 HLAESESLLTSPPK 14 0 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 HLAES(0.003)ES(0.001)LLT(0.564)S(0.433)PPK;HLAESES(0.001)LLT(0.624)S(0.375)PPK 105.0 0.0024763000000000003 18007500.0 124623.0 127921.0 133246.0 134681.0 151650.0 179623.0 166454.0 157507.0 156057.0 152551.0 True False 164250.5216805692 169268.96161850347 131479.07097861014 103632.37625070747 130596.0151695438 168391.14541466118 181268.08353587473 133167.9123007915 164305.8544233202 147210.23592291027 1.115754761554641 1.1498450536221185 0.8931381038439603 0.7039753424821406 0.8871395005299301 1.1438820429772474 1.231355159506704 0.9046104128963401 1.116130637202174 1.0 17.167518463778777 -6.760428867909588 24.99957216988194 1.0827437727950588 0.9442509300252385 0.1713444059878857 0.1417057086773757 53.74326372938138 1329588.3535675309 0.05354436173845293 0.05065134278332721 1.7360855890362869e-07 6.760428867909588 -0.13849284276982032 HLAESESLLT(ph)SPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HLAESESLLTSPPK 14 0 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 HLAESESLLT(0.729)S(0.271)PPK;HLAESESLLT(0.5)S(0.5)PPK 108.06 0.0015122 27836000.0 102321.0 105877.0 93209.0 116172.0 101230.0 102933.0 138797.0 105107.0 96594.0 89899.0 True False 119641.92436813074 116387.7688432837 95431.45605710092 109663.25947470583 81394.70818563552 97535.01227680955 125649.14335674023 102348.05262007177 98006.50451210546 106196.97705990759 1.1266038608673261 1.095961222866328 0.8986268601908165 1.0326401232008973 0.766450330688032 0.9184349213799968 1.1831706215691933 0.9637567419865015 0.9228747109893558 1.0 16.696383174262955 -5.152678157370621 5.777968767508911 0.9617597492200682 1.1179919313121192 0.2648694235082947 0.10063151580515362 0.3163712542148061 14.120989511632272 0.026907437643883123 0.07433844059241766 7.035935388225593e-06 5.152678157370621 0.15623218209205092 HLAESESLLTS(ph)PPK ddPTM_PC-9_AZD4547_30min_R2 3 HLAESESLLTSPPK 14 0 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 HLAESESLLT(0.112)S(0.888)PPK;HLAESESLLT(0.249)S(0.751)PPK;HLAESESLLT(0.315)S(0.685)PPK 145.94 0.00010774 52840000.0 365210.0 362199.0 388667.0 350277.0 389175.0 462310.0 450570.0 449200.0 425003.0 448620.0 True False 481339.1831600946 479272.7435625143 383513.02162949403 269526.0493757032 335144.76889948663 433401.6826166581 490669.85713025247 379786.46158910694 447467.7909191787 432913.95034929976 1.1118587949677357 1.1070854685459077 0.8858874178576454 0.6225857336272813 0.7741602427666575 1.001126626358344 1.1334119788340198 0.8772793329544439 1.0336183219739998 1.0 18.723720765574917 -8.282000351843745 23.702518172944973 1.0168091874598604 0.9354814705816298 0.03908833127077471 0.15309575695308866 2098.952855558064 2419612.394181041 0.1643172767509198 0.04268122034324856 5.223957657799336e-09 8.282000351843745 -0.0813277168782306 HLAESESLLTS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HLAESESLLTSPPK 14 0 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 HLAESESLLT(0.246)S(0.754)PPK;HLAESESLLT(0.139)S(0.861)PPK 110.57 0.00027315 30176000.0 138449.0 187342.0 158752.0 180055.0 167309.0 141278.0 197659.0 162360.0 133511.0 132623.0 True False 161885.68120760514 205940.07565985448 162537.2497503125 169967.1020961865 134526.0024877059 133869.13297429492 178935.30859276478 158098.22203464 135463.3457970034 156666.50005690978 1.03331395766676 1.3145125191731855 1.0374729102346076 1.084897550110874 0.8586775247984653 0.8544847362114197 1.142141482242635 1.009138660640342 0.8646605735610086 1.0 17.25733719624722 -5.746447577355247 2.1027305992728356 0.9630891248709788 1.1678513116173768 0.33879391223797317 0.11042595443052386 0.3474676655006892 3.1323148764326527 0.033581801952296014 0.06595581716898358 1.7928849541451021e-06 5.746447577355247 0.204762186746398 HLAESESLLTS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 4 HLAESESLLTSPPK 14 0 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 HLAESESLLT(0.186)S(0.814)PPK;HLAESESLLT(0.195)S(0.805)PPK;HLAESESLLT(0.139)S(0.861)PPK;HLAESESLLT(0.214)S(0.786)PPK 123.28 4.0861e-05 62978900.0 215004.0 288845.0 253880.0 257253.0 289648.0 319077.0 313213.0 319309.0 295185.0 269661.0 True False 211938.0035330954 288176.19714908436 233006.96640514082 276172.2437908512 272611.47410987795 305430.8205148155 329429.636577021 334145.2618348144 261938.1568641466 316271.5445493029 0.6701140434088494 0.9111670085898644 0.7367307316160334 0.8732124294786163 0.861953845700403 0.9657233658186488 1.0416037808474639 1.0565138331081354 0.8282065249892047 1.0 18.270804234578137 -6.464559291800314 1.4390636012845786 0.9887292761430259 0.7895053965769582 0.5170729254359152 0.08382943025470098 0.3295736184564004 1.3918341448689944 0.03293856540998009 0.038375479133611515 3.4311579291557935e-07 6.464559291800314 -0.19922387956606769 HLAGEVAK ddPTM_PC-9_AZD4547_30min_R2 2 HLAGEVAK 8 0 Q13200;Q13200-3 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 0 ; 81.548 0.01617 1239300.0 32070.0 28325.0 33974.0 45937.0 40790.0 39417.0 30787.0 39876.0 33305.0 39461.0 False True 42267.59290256088 37480.50232443548 33523.48256178275 35346.93436957513 35127.012586651384 36952.248758843256 33526.983357678204 33714.08045932156 35065.43430649492 38079.482400993606 1.109983388362915 0.9842702673778335 0.8803555208226261 0.9282409355609526 0.9224656001557106 0.9703978738397732 0.8804474547375515 0.8853607857453929 0.92084850149066 1.0 15.21672624835826 -4.848429741019456 2.9134502827668687 0.9198534522444334 1.128487414436051 0.7011753283625577 0.03691463927763245 0.17609071027653583 2.340951418433208 0.00923098300153423 0.0812212230731725 1.4176540371083428e-05 4.848429741019456 0.20863396219161767 HLAGEVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HLAGEVAK 8 0 Q13200;Q13200-3 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 0 82.45200000000001 0.015507 0.0 23058.0 25118.0 25438.0 29786.0 32250.0 29288.0 29257.0 31440.0 30838.0 27971.0 False True 26961.263983741002 27611.54904092107 26044.538394152223 28117.186987514928 25930.84400856208 27752.085721422685 26485.565157662986 30614.733313433557 31288.947410235756 33041.92088168585 0.8159714467049893 0.8356520536378781 0.7882271278177393 0.8509549758984939 0.7847862145004642 0.8399053378523412 0.8015746194811314 0.92654217722561 0.9469469865953914 1.0 15.012009939367582 -7.95326572620429 2.206948833725416 0.9775071899957386 0.8164364709293859 0.8725095478940935 0.02494751529729409 0.09796941541168261 0.8976021748845185 0.018187553286627727 0.006436644049776117 1.1136129529982393e-08 7.95326572620429 -0.16107071906635273 HLAGEVAK ddPTM_PC-9_Lapatinib_30min_R1 1 HLAGEVAK 8 0 Q13200;Q13200-3 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 0 103.83 0.0032461999999999994 1740900.0 36187.0 34294.0 32445.0 34154.0 38509.0 29610.0 30447.0 34868.0 40178.0 32309.0 False True 35670.96674411694 34214.59435001707 29777.49734132184 36665.79909440405 36243.97633160699 28343.649324281287 32023.396681684848 36488.09457189216 35652.73054690347 37893.5676009636 0.9413462231835319 0.9029129880382923 0.7858193151643136 0.9675995535841727 0.9564677760952055 0.7479804916431393 0.8450879320444487 0.9629099839880026 0.9408649753526203 1.0 15.209665352542617 -7.775932984290204 23.903336659872256 0.963915711488727 0.8770162730812869 0.2633892368723818 0.06866426970414682 220.75410283857485 364066.26162016555 0.03901664745646981 0.018894290808489672 1.6752013553561258e-08 7.775932984290204 -0.08689943840744008 HLAGLGLTEAIDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HLAGLGLTEAIDK 13 0 P50454;E9PKH2 P50454 SERPINH1 Serpin H1 0 93.01100000000001 0.0072043 0.0 32291.0 28364.0 24755.0 31679.0 33302.0 29815.0 34739.0 26185.0 27293.0 19542.0 False True 37757.228523678605 31179.790468854415 25345.253083860287 29904.12833470374 26776.71216040728 28251.4489136922 31448.27043141996 25497.671495300823 27692.108491716877 23084.80990561313 1.6355875867315608 1.3506626477038033 1.0979190726494796 1.2954028409578748 1.1599277737130709 1.2238112000576964 1.3622928046625689 1.1045216139770335 1.1995813959457156 1.0 14.494656231955858 -4.85594473937674 2.890738322177168 1.1958052378820438 1.6763765601133973 0.6648413565649511 0.09877843209995066 0.19848834098105142 2.6140007429441185 0.024168096630037016 0.20824580456301842 1.3933340826820438e-05 4.85594473937674 0.48057132223135346 HLAGLGLTEAIDK ddPTM_PC-9_Lapatinib_30min_R1 2 HLAGLGLTEAIDK 13 0 P50454;E9PKH2 P50454 SERPINH1 Serpin H1 0 ; 98.40700000000001 0.0023221 4736200.0 68648.0 78030.0 79400.0 69201.0 76661.0 76179.0 74680.0 68643.0 70980.0 69429.0 False True 67669.06693149847 77849.32632914883 72872.03849286358 74290.27238776867 72151.95070132495 72921.00175192243 78546.56498795359 71832.40437359156 62985.48494746394 81429.71014167277 0.8310120079485326 0.9560309891034277 0.8949072564065326 0.9123239203297815 0.8860641966647528 0.8955085511793331 0.9645934493847144 0.8821399983939074 0.7734951387875598 1.0 16.313267646445716 -6.249920973510721 21.61662804607587 0.8973822970303855 0.9024114643056945 0.0 0.062359605670889544 2559.9905698130924 4804283.943742283 0.01825092083596738 0.02326613502380905 5.624436610616479e-07 6.249920973510721 0.005029167275308999 HLAPPPLLS(ph)PLLPSIKPTVR ddPTM_PC-9_AZD4547_30min_R2 1 HLAPPPLLSPLLPSIKPTVR 20 1 Q14676;Q14676-3;Q14676-2;H0Y6Z8 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 HLAPPPLLS(1)PLLPSIKPTVR 82.56 0.00044259 4912000.0 33827.0 36080.0 52401.0 66595.0 51780.0 45085.0 40610.0 55021.0 43422.0 49209.0 True False 44583.282354690564 47742.154417145015 51706.12850179486 51242.551632493596 44591.24078785998 42265.827822828964 44224.21132800574 46518.76870679934 45717.198272230075 47486.20788805391 0.9388680279502033 1.0053899129973587 1.0888662371964757 1.0791038895608396 0.9390356225744819 0.8900653411295402 0.9313064423308312 0.9796269438162918 0.9627468754718385 1.0 15.535220930870212 -6.280474193818406 24.522422742952664 0.945467112063057 1.0307814539621472 0.38754243227282004 0.04748923608724424 666.4970609396556 858641.2712753905 0.015930511303567776 0.01809425904166052 5.242347505989038e-07 6.280474193818406 0.08531434189909015 HLAPPPLLS(ph)PLLPSIKPTVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HLAPPPLLSPLLPSIKPTVR 20 1 Q14676;Q14676-3;Q14676-2;H0Y6Z8 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 HLAPPPLLS(1)PLLPSIKPTVR;HLAPPPLLS(1)PLLPSIKPTVR 102.29 9.8311e-05 4322000.0 38363.0 38120.0 36385.0 41645.0 45180.0 44588.0 42685.0 37623.0 35741.0 33069.0 True False 44857.098196212 41904.301673696595 37252.556390880934 39311.76566491167 36327.303327343696 42249.72678731203 38641.56778736181 36635.436114863616 36263.64450967106 39064.14792594003 1.1482932708849702 1.072704868749245 0.9536252131111727 1.0063387467055749 0.9299397339016585 1.0815473786196845 0.9891824048132479 0.9378276004974971 0.9283101369168907 1.0 15.25355752576505 -5.016171117404257 2.936507909189933 0.9795354818195009 1.1470392440392756 0.6094898900079085 0.04415221320672067 0.19074137557231202 3.087068675215379 0.011902794776251219 0.058262053037665 9.634493378577762e-06 5.016171117404257 0.1675037622197747 HLAPPPLLS(ph)PLLPSIKPTVR ddPTM_PC-9_Lapatinib_30min_R1 1 HLAPPPLLSPLLPSIKPTVR 20 1 Q14676;Q14676-3;Q14676-2;H0Y6Z8 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 HLAPPPLLS(0.999)PLLPSIKPTVR 46.159 0.032795 3313800.0 23100.0 18621.0 23892.0 18096.0 21799.0 21207.0 23210.0 22875.0 25134.0 21673.0 True False 22770.589763978805 18577.884218570838 21927.691985787045 19426.84020648636 20516.825678482954 20300.026045931536 24411.70023259781 23937.856009293144 22303.14424724654 25419.14917254277 0.8958045609400301 0.7308617645880248 0.8626446084778037 0.7642600495641617 0.8071405356338519 0.7986115470717328 0.960366535751984 0.9417253050763128 0.8774150580672435 1.0 14.633628120942829 -7.258179824262179 24.94523000042865 0.9400205035398422 0.8064943667321844 0.6206579003349952 0.0516038721066821 177.83333066661413 1360957.6883066583 0.01889874781867952 0.01402721671597144 5.51848893048136e-08 7.258179824262179 -0.1335261368076578 HLDAHTAAHS(ph)QSPR ddPTM_PC-9_AZD4547_30min_R2 1 HLDAHTAAHSQSPR 14 0 H7C3X3;H0Y6N5;E9PHI4;O94901-9 H7C3X3 SUN1 1 HLDAHT(0.001)AAHS(0.5)QS(0.5)PR 64.454 0.035552 964090.0 3988.9 3867.0 6742.8 8808.2 6043.8 4266.2 5588.5 8078.9 3919.2 4463.9 True False 5257.287225725756 5116.932126693454 6653.386066332744 6777.605575333431 5204.722693581851 3999.4338395864024 6085.865673640975 6830.491639653249 4126.360910794619 4307.620219705415 1.2204621014814732 1.1878791225108014 1.5445618989103334 1.5733990532240862 1.2082594165968015 0.9284555359107102 1.4128138886991222 1.5856763807558607 0.9579212419698427 1.0 12.072675345291662 -6.406502269125737 20.447711132929623 1.2102476302588976 1.3808331171656518 0.15454196800353381 0.2227342422898054 12.603905368651374 2176.799482714349 0.0728328542346802 0.08258455574016185 3.921910971856437e-07 6.406502269125737 0.17058548690675424 HLDAHTAAHSQS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HLDAHTAAHSQSPR 14 0 H7C3X3;H0Y6N5;E9PHI4;O94901-9 H7C3X3 SUN1 1 HLDAHTAAHS(0.163)QS(0.836)PR 70.235 0.024047 1153700.0 4894.6 3652.5 5708.2 4227.9 7035.7 5298.6 3670.3 4064.2 5043.5 3678.5 True False 5723.159107243415 4015.096061468437 5844.305136469053 3991.024470036741 5657.105091195047 5020.732088347798 3322.6226133291316 3957.519056375849 5117.251646135421 4345.382931010024 1.3170666885077367 0.9239913087556553 1.344945941302951 0.9184517298937066 1.3018657230008799 1.1554176393795514 0.764632868053549 0.9107411519785159 1.1776296191567142 1.0 12.08526760285858 -7.194408326608238 24.785311087516437 0.9558124043788281 1.1533853432051029 0.2466226105845939 0.1682526346579601 235.21033495674376 86970.6657010816 0.06116845583491606 0.04738087457218144 6.39133635135554e-08 7.194408326608238 0.1975729388262748 HLDFLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HLDFLK 6 0 P46821;D6RA32;D6RA40;C9JKF1;Q5K651;Q8IVG5 P46821;Q8IVG5 MAP1B;SAMD9;SAMD9L Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1;Sterile alpha motif domain-containing protein 9;Sterile alpha motif domain-containing protein 9-like 0 101.52 0.029736000000000002 1500400.0 17110.0 20478.0 19463.0 19144.0 21686.0 17362.0 21599.0 18845.0 16259.0 16047.0 False True 20006.38506209595 22510.920505612776 19927.071733838544 18071.423745685424 17436.783974253558 16451.506155945794 19552.986356781712 18350.33871792797 16496.757115994016 18956.194072017905 1.0554009410374352 1.1875232137891099 1.0512169087387535 0.9533255292190467 0.9198462469843978 0.8678696838322945 1.0314827059955436 0.9680391880464938 0.8702568170234987 1.0 14.210381715906106 -5.630469132643514 3.208006235800509 0.9417721801280629 1.1221190395408014 0.6186374137414128 0.05688853983030546 0.14985687325821156 3.0411350117385214 0.015892536691836903 0.03027046243035725 2.3416979047657423e-06 5.630469132643514 0.18034685941273854 HLDGEEDGS(ph)SDQSQASGTTGGR ddPTM_PC-9_AZD4547_30min_R2 2 HLDGEEDGSSDQSQASGTTGGR 22 0 Q5H909;Q9UNF1-2;Q9UNF1;Q5H907 Q5H909 MAGED2 Melanoma-associated antigen D2 1 HLDGEEDGS(0.776)S(0.224)DQSQASGTTGGR;HLDGEEDGS(0.945)S(0.055)DQSQASGTTGGR 117.61 6.9315e-05 0.0 4951.6 5090.8 9591.900000000001 16317.300000000001 11279.099999999999 11714.5 12217.0 12782.3 4961.700000000001 8556.1 True False 6526.1058003218095 6736.30154398009 9464.705138763875 12555.598584771942 9713.191656437844 10981.990463136965 13304.289332534983 10807.089243033053 5223.965332488691 8256.553543274149 0.7904152460366498 0.8158732949134124 1.1463263805118658 1.5206827544889874 1.1764220513473547 1.3300937740642373 1.6113611160885353 1.3089104535434872 0.6327053176738826 1.0 13.011323981121643 -5.32383076718611 3.7804959301087204 1.261031587987618 0.7949337414912248 0.28485197037797005 0.2588475142102377 0.25841460381977543 7.344182475659083 0.070018714875894 0.1680903735431602 4.744268205461099e-06 5.32383076718611 -0.4660978464963932 HLDGEEDGS(ph)SDQSQASGTTGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HLDGEEDGSSDQSQASGTTGGR 22 0 Q5H909;Q9UNF1-2;Q9UNF1;Q5H907 Q5H909 MAGED2 Melanoma-associated antigen D2 1 HLDGEEDGS(0.809)S(0.191)DQSQASGTTGGR;HLDGEEDGS(0.565)S(0.435)DQSQASGTTGGR 146.75 5.747e-06 9962400.0 8477.5 10403.8 13804.7 10031.8 15072.6 14240.5 14205.1 10657.7 8009.1 10960.4 True False 9912.573311742755 11436.620507681122 14133.856402616293 9469.750769534423 12119.232229564435 13493.70311103249 12859.490091982036 10377.946667766575 8126.217935771422 12947.433757521336 0.765601392321039 0.8833117606056442 1.0916338069237659 0.7313998238479744 0.9360335381151661 1.042191322523185 0.9932076373444882 0.8015446815271705 0.6276315513914713 1.0 13.660378556829569 -7.86682827881603 7.155787391827701 0.7821211326915166 0.9233771512218435 0.11506210041689602 0.13500086112025306 0.39650179951775694 23.86126543713154 0.07349742532473066 0.0350665158311473 1.3588506335032194e-08 7.86682827881603 0.14125601853032688 HLDGEEDGS(ph)SDQSQASGTTGGR ddPTM_PC-9_Lapatinib_30min_R1 1 HLDGEEDGSSDQSQASGTTGGR 22 0 Q5H909;Q9UNF1-2;Q9UNF1;Q5H907 Q5H909 MAGED2 Melanoma-associated antigen D2 1 HLDGEEDGS(0.788)S(0.212)DQSQASGTTGGR 103.71 2.7275e-05 6674300.0 3787.8 5316.8 6516.7 5836.7 6905.1 6040.2 5003.3 5946.3 7863.2 4589.1 True False 3733.785277402551 5304.489276263215 5980.922081189456 6265.950388660423 6498.955593948928 5781.874726393912 5262.346392665082 6222.586806035398 6977.563612833173 5382.31982040862 0.6937130088860245 0.9855395913393538 1.1112164049618647 1.1641728098172952 1.20746366080036 1.074234701637436 0.9777097177895999 1.1561161383314054 1.2963859164176244 1.0 12.394012403921502 -4.752546230355836 1.912407808966995 1.1274996344464827 0.5373463528742564 0.6846984707369083 0.0888154656247555 0.5166559033253677 1.8969973393043702 0.024954793679866947 0.5625614011944373 1.7678840176516096e-05 4.752546230355836 -0.5901532815722264 HLDGEEDGSS(ph)DQSQASGTTGGR ddPTM_PC-9_Lapatinib_30min_R1 1 HLDGEEDGSSDQSQASGTTGGR 22 0 Q5H909;Q9UNF1-2;Q9UNF1;Q5H907 Q5H909 MAGED2 Melanoma-associated antigen D2 1 HLDGEEDGS(0.366)S(0.414)DQS(0.204)QAS(0.007)GT(0.007)T(0.002)GGR 57.738 0.041711 0.0 1427.7 3973.9 4787.7 1370.4 4163.9 5264.1 2056.5 1584.5 4708.2 1328.7 True False 1407.3407361918858 3964.698678705688 4394.073787056447 1471.1837875203864 3918.9875885423717 5038.966714216445 2162.97550746822 1658.1216545016377 4177.912936456039 1558.3640246185387 0.903088568498223 2.5441415587581853 2.81967096111067 0.9440565646274512 2.514808816573954 3.2334978442857083 1.387978337088268 1.064014330610281 2.680960847693286 1.0 10.605816562457104 -10.28725371370165 9.12876267123633 1.0000000242856788 2.023082997083886 0.11902591253555173 0.8238696655109263 0.0 0.0 0.7965374647146283 0.19318871186941844 5.161147682842111e-11 10.28725371370165 1.0230829727982074 HLDRS(ph)PESDRPR ddPTM_PC-9_Lapatinib_30min_R1 1 HLDRSPESDRPR 12 2 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 HLDRS(0.98)PES(0.02)DRPR 69.346 0.010346 8022300.0 13240.0 7666.9 15508.0 10375.0 10637.0 8722.6 9137.5 8954.4 7827.7 7618.0 True False 13051.195172081358 7649.147764102931 14232.992102611159 11138.01210998542 10011.352573146622 8349.554731373717 9610.595039869126 9370.454113644353 6946.061996664745 8934.761149653057 1.4607212160996765 0.8561110516535692 1.5929907766100535 1.2465931571565196 1.1204947066251871 0.9345022873608586 1.0756409577039798 1.0487638065185676 0.7774199981758286 1.0 13.125213447301332 -6.4689690563157844 2.8257529636165764 0.9776068253357385 1.2794506680352729 0.3822197104834676 0.19219580189789132 0.3122003674549582 4.9413304311456185 0.06381898018091138 0.07043857596885437 3.3964947191144106e-07 6.4689690563157844 0.30184384269953435 HLDVPDIIITPPT(ph)PTGMMLPR ddPTM_PC-9_AZD4547_30min_R2 4 HLDVPDIIITPPTPTGMMLPR 21 0 R4GN89;R4GMY0;Q96GX8 R4GN89 C16orf74 Uncharacterized protein C16orf74 1 HLDVPDIIITPPT(0.79)PT(0.21)GMMLPR;HLDVPDIIIT(0.159)PPT(0.527)PT(0.314)GMMLPR;HLDVPDIIITPPT(0.753)PT(0.247)GMMLPR;HLDVPDIIIT(0.038)PPT(0.781)PT(0.181)GMMLPR 84.249 0.00046772 33330400.0 97586.0 167568.0 177497.0 189002.0 166082.0 105969.0 141986.0 182235.0 137363.0 129192.0 True False 128616.31808510433 221731.0790291619 175143.2738055203 145430.50895179142 143024.38108399717 99342.74167810472 154622.47893667125 154074.76809370186 144623.72774787742 124669.02740298434 1.0316621599153142 1.7785578635536388 1.4048659675460635 1.1665327947229183 1.1472326692794383 0.796851822361507 1.2402637780823007 1.235870458792186 1.1600614102842948 1.0 16.927743563002352 -5.790480046573957 3.753748704561942 1.1056939366742586 1.4482843898770963 0.3026303975381087 0.20723402999799395 0.2483363271409275 7.416189283219769 0.058398200453679786 0.09616597142853575 1.6200184230676555e-06 5.790480046573957 0.34259045320283765 HLDVPDIIITPPT(ph)PTGMMLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HLDVPDIIITPPTPTGMMLPR 21 0 R4GN89;R4GMY0;Q96GX8 R4GN89 C16orf74 Uncharacterized protein C16orf74 1 HLDVPDIIIT(0.001)PPT(0.713)PT(0.286)GMMLPR 77.08 0.0015461 16764000.0 53779.0 48142.0 44222.0 39838.0 97752.0 42332.0 46678.0 49914.0 45748.0 44158.0 True False 62882.722516333066 52921.21960060599 45276.42019286891 37606.006016538646 78598.19731860352 40112.035398773034 42256.32192054527 48603.81038825454 46416.97795328705 52163.49584546433 1.2054928738408315 1.0145259389322072 0.8679713554283525 0.7209257241490752 1.5067662940277748 0.7689675461477112 0.8100745787002215 0.9317590702173135 0.8898364114782207 1.0 15.670752937575362 HLDVPDIIITPPT(ph)PTGMMLPR ddPTM_PC-9_Lapatinib_30min_R1 1 HLDVPDIIITPPTPTGMMLPR 21 0 R4GN89;R4GMY0;Q96GX8 R4GN89 C16orf74 Uncharacterized protein C16orf74 1 HLDVPDIIIT(0.001)PPT(0.931)PT(0.068)GMMLPR 78.78 0.0013061 4814300.0 42592.0 42822.0 21270.0 13512.0 20353.0 19499.0 13262.0 12495.0 28279.0 9073.5 True False 41984.63026958378 42722.84828997585 19521.262704574354 14505.717554710644 19155.87655553759 18665.07322438908 13948.641468535636 13075.56331524012 25093.92122892834 10641.842385321226 3.9452407533769787 4.014610134510675 1.8343875052595136 1.3630832922989946 1.8000526470830047 1.7539325004601327 1.3107355816297024 1.2286935703234843 2.358042932823504 1.0 13.377460320808465 -5.288953489451885 4.52629675799824 1.5691571972338791 4.013987807218011 0.8783228693579307 0.3580721365563787 0.054646959788493654 2.8342386316580734 0.09064143248228791 0.21535675091008039 5.1409870577552344e-06 5.288953489451885 2.4448306099841317 HLEFSHDQYR ddPTM_PC-9_AZD4547_30min_R2 2 HLEFSHDQYR 10 0 Q9NR45 Q9NR45 NANS Sialic acid synthase 0 ; 120.27 0.00030279 56080000.0 47450.1 55406.4 64215.3 92127.0 80932.0 81119.4 53788.2 71696.1 58780.6 70200.1 False True 62538.24477660754 73315.43526879438 63363.76316446832 70888.54349796136 69695.9887880086 76046.99109440375 58575.24559844959 60617.115157477245 61887.622513026705 67742.41586624745 0.923177066789068 1.0822677982661624 0.9353632041935961 1.046442507127672 1.028838252914073 1.1225904792730317 0.8646760652011912 0.8948177354223888 0.9135727110060465 1.0 16.047771817460728 -7.279645209958253 24.998773148191116 0.9095014375256496 1.023134082949285 0.38252677972523186 0.06487744172478513 810.3161797847354 1112656.331863926 0.026055769330737406 0.017601280486271652 5.252363686157362e-08 7.279645209958253 0.11363264542363538 HLEFSHDQYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HLEFSHDQYR 10 0 Q9NR45 Q9NR45 NANS Sialic acid synthase 0 ;;; 142.98 5.3809e-05 36730500.0 333773.4 278467.4 333626.6 333644.2 392667.1 328469.9 328044.5 290129.4 289592.1 291539.2 False True 390274.64429485606 306111.803145066 341581.5234299264 314951.1971630906 315726.80053936294 311244.3602057886 296969.7501234906 282513.81066750933 293826.8366080725 344392.949136963 1.1332248388733597 0.8888445710406435 0.9918365758820501 0.9145111650872864 0.9167632535177145 0.9037477712181865 0.8622991581787219 0.8203240263062276 0.853173206200628 1.0 18.393696080733513 -1.5228787452803376 0.9268001437369834 0.8908067417599974 133.8468300113619 0.5645488296804109 0.05726719061670093 766.9716039205364 1.4884557311822295 0.018813749249621065 215970.77594371155 0.029999999999999995 1.5228787452803376 132.9560232696019 HLEFSHDQYR ddPTM_PC-9_Lapatinib_30min_R1 2 HLEFSHDQYR 10 0 Q9NR45 Q9NR45 NANS Sialic acid synthase 0 ; 88.134 0.004283100000000001 35114000.0 151134.0 117206.0 137105.0 106845.0 121961.0 114547.0 111291.0 104401.0 133593.0 82774.0 False True 148978.80144541844 116934.616708115 125832.75614060475 114702.73772447128 114787.49376455153 109648.09183209877 117053.10342895491 109251.85159458859 118546.34954334381 97081.37561057803 1.5345765396136974 1.204501027850843 1.296157531238092 1.1815112528336817 1.1823842940277025 1.1294451808339587 1.2057215165397879 1.1253636540218581 1.2211029025677191 1.0 16.566906930688873 -1.5228787452831325 0.7958984193958856 1.156600697700652 86.6618046147765 0.7061701249114467 0.0711390463692695 257.8530164691856 0.9137466134809938 0.023483000996265633 39735.98387822654 0.029999999999806935 1.5228787452831325 85.50520391707585 HLEINPDHPIVETLR ddPTM_PC-9_AZD4547_30min_R2 2 HLEINPDHPIVETLR 15 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 ; 158.31 7.1177e-05 43397000.0 52795.0 51306.0 68442.0 86181.0 65384.0 60536.0 46808.0 66688.0 53281.0 54975.0 False True 69582.71179578123 67889.66115648678 67534.41436079159 66313.30193317703 56306.560209993 56750.67435028884 50973.8213208887 56382.901937787996 56097.32488468264 53050.34198308768 1.3116354993142934 1.2797214611383625 1.2730250519840456 1.2500070584713205 1.0613797782480534 1.0697513386130635 0.9608575442763222 1.062818821333192 1.0574356882103857 1.0 15.695074430891458 -6.254525094268446 2.2840535723670183 1.0294069589054111 1.2889379987856686 0.9347169445989993 0.03168902629175547 0.07188276943882231 0.737244737181297 0.010646306772874805 0.013693748768449022 5.565124770986533e-07 6.254525094268446 0.2595310398802575 HLEINPDHPIVETLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HLEINPDHPIVETLR 15 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 130.27 5.385700000000001e-06 13453000.0 12462.0 12090.0 14493.0 15614.0 15226.0 14139.0 15296.0 12937.0 14103.0 9715.6 False True 14571.570464280521 13290.215299973543 14838.568085008572 14739.198201271 12242.57460075555 13397.52594971304 13847.052146549977 12597.417457884545 14309.229694745274 11476.961371352712 1.2696366218197934 1.1579907668894693 1.2929004119545668 1.2842422070062076 1.066708704911551 1.16734085932834 1.2065085608036614 1.0976265450651919 1.2467785881428597 1.0 13.486453105643497 -14.522878744906418 0.1175379734438864 0.3833660045433255 1.2915205062040185 0.43165453511524843 0.07130677116200085 155.84268474245752 1.1906794467175554 23.031637300911285 0.7374467091942684 3.0000000025829458e-15 14.522878744906418 0.908154501660693 HLEINPDHPIVETLR ddPTM_PC-9_Lapatinib_30min_R1 2 HLEINPDHPIVETLR 15 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 ; 164.93 0.00012362 78930000.0 59926.0 53208.0 50863.0 53054.0 53255.0 55911.0 53683.0 49957.0 58151.0 50944.0 False True 59071.44425091752 53084.800145089765 46681.24047685784 56955.7681429558 50122.64560335843 53519.81686490679 56462.44306706368 52278.18459699483 51601.42202282301 59749.60252138696 0.9886499952827854 0.8884544483135001 0.781281188609558 0.9532409545748672 0.8388783102852839 0.8957351113047111 0.9449844130235567 0.8749545166979515 0.8636278710699814 1.0 15.866641495281643 -7.007944973750877 24.68136315878765 0.9118838902363219 0.8854552389612139 0.0407114134334281 0.06389617727762886 1364.346796627612 4238407.919163457 0.02294626152016037 0.019360600993016397 9.81872340938085e-08 7.007944973750877 -0.02642865127510796 HLEINPDHSIIETLR ddPTM_PC-9_AZD4547_30min_R2 4 HLEINPDHSIIETLR 15 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ;;; 165.78 4.9851e-05 120400000.0 95354.0 91559.0 123317.0 160344.0 133685.0 115786.0 105504.0 152744.0 109221.0 116051.0 False True 125674.588513589 121153.65621616897 121681.73600610349 123379.168090105 115125.14532107115 108545.88311620419 114893.6516116698 129140.92450793958 114994.19908090921 111988.0898131754 1.1222138775940027 1.0818441176939804 1.086559617269118 1.1017168727132753 1.0280124030432982 0.96926274300496 1.0259452751032867 1.153166597656764 1.0268431158415932 1.0 16.77298578099515 -6.258860995118968 24.77373203157566 1.037903250334898 1.0961005158277444 0.3198203505854582 0.0456121571728826 305.13846199176504 2931846.1308295443 0.01482458860848537 0.018240199542145057 5.509840219538584e-07 6.258860995118968 0.05819726549284643 HLEINPDHSIIETLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 HLEINPDHSIIETLR 15 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ;;;;; 175.01 1.8705e-05 92011400.0 91038.5 112323.09999999999 103042.4 101900.2 107137.8 99060.0 114207.7 92123.5 89847.9 72160.7 False True 106449.51995766365 123473.79505049267 105499.32160647794 96191.06215890568 86144.9171851326 93865.11921483655 103389.11986385568 89705.35573791653 91161.75556197287 85242.86368621318 1.2487792567541387 1.4484942165365426 1.2376323019230167 1.128435366894686 1.010582158551594 1.1011492945657326 1.2128771300368384 1.0523503300889818 1.0694356292105305 1.0 16.379291440015223 -5.6452493697241755 2.8412757725054245 1.085247381843562 1.3490403079786997 0.6918269031187716 0.07265558541960894 0.1410541027140415 2.279603454233351 0.020449987266288387 0.03977588339894576 2.2633443333883453e-06 5.6452493697241755 0.2637929261351377 HLEINPDHSIIETLR ddPTM_PC-9_Lapatinib_30min_R1 4 HLEINPDHSIIETLR 15 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ;;; 191.19 4.4890999999999995e-08 80746600.0 78854.0 75369.0 83932.0 74217.0 71628.0 81289.0 64362.0 70013.0 77329.0 69721.0 False True 77729.52749994726 75194.48771115774 77031.43494688942 79675.16576065434 67414.9818660663 77812.45896391418 67694.34943431536 73266.05957502247 68619.39370953008 81772.18195260712 0.9505619838418539 0.9195607346608211 0.9420249418259953 0.9743553841675872 0.8244243978366402 0.9515761608148369 0.8278408111153145 0.8959777986294342 0.8391532679083942 1.0 16.3193225163026 -6.241996789440953 24.865461588720354 0.8846155975733356 0.9443639136155978 0.21021451787417067 0.053289899917730046 1115.8461950305755 1427074.400368095 0.014576755194965544 0.018786843689301426 5.72800265445058e-07 6.241996789440953 0.05974831604226216 HLELYDR ddPTM_PC-9_AZD4547_30min_R2 1 HLELYDR 7 0 H0Y8P4;Q8TED0-3;Q8TED0;Q8TED0-2 H0Y8P4 UTP15 U3 small nucleolar RNA-associated protein 15 homolog 0 127.12 6.0608000000000005e-06 0.0 3178.5 3432.7 5075.6 5349.4 5210.2 3897.2 3805.2 4734.6 4354.6 4095.8 False True 4189.196883092914 4542.2531448928385 5008.294227661877 4116.178477406125 4486.853664598458 3653.5074679190193 4143.855428350833 4002.976360284478 4584.775265907905 3952.407288664492 1.0599102210714808 1.1492371137762105 1.2671503369669592 1.0414358077952464 1.1352204711965688 0.924375248066484 1.048438363180691 1.0127944991309519 1.1599956510193281 1.0 11.948515906448089 -6.174828132250086 2.093039380937848 1.0364662751674303 1.1525458299651292 0.2501182327246577 0.08090561084902494 0.42911598590157674 3.6932351359250175 0.026609586545182397 0.036666582001624044 6.686084604116868e-07 6.174828132250086 0.11607955479769894 HLELYDR ddPTM_PC-9_Lapatinib_30min_R1 1 HLELYDR 7 0 H0Y8P4;Q8TED0-3;Q8TED0;Q8TED0-2 H0Y8P4 UTP15 U3 small nucleolar RNA-associated protein 15 homolog 0 116.88 0.0063784 2274500.0 4396.2 3442.5 5167.4 3228.3 3571.3 3696.0 4271.6 4338.5 2551.1 2534.8 False True 4333.5093818356545 3434.5291027565704 4742.5563187408325 3465.719951293102 3361.243155445946 3537.930695796812 4492.76254690068 4540.082548472933 2263.768253726053 2972.9368025913086 1.4576527082776958 1.1552647536143126 1.5952428973959574 1.1657563484942792 1.1306137259682671 1.1900457126142192 1.5112203337066035 1.5271372551598301 0.7614585859184355 1.0 11.537673080044481 -8.26738542347642 24.963207518232128 0.8807292517465241 1.3315648339958739 0.5277658624055119 0.1741789915130242 417.18474244392763 1751434.015983523 0.15613013317558758 0.04451828572347804 5.402746324036839e-09 8.26738542347642 0.45083558224934983 HLFS(ph)STENLAAGSWK ddPTM_PC-9_AZD4547_30min_R2 1 HLFSSTENLAAGSWK 15 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 HLFS(0.605)S(0.18)T(0.215)ENLAAGSWK 62.438 0.024425 42507000.0 29414.0 39208.0 53183.0 53763.0 48223.0 61335.0 66973.0 82554.0 69928.0 61068.0 True False 38767.0401507928 51881.21924577109 52477.75867084509 41368.77098006983 41528.0688395707 57499.71275398058 72933.46725610737 69797.1762021975 73624.25131915865 58930.02790765253 0.6578486643777509 0.8803868093711509 0.8905096524488568 0.7019981569480601 0.7047013265401483 0.9757285851635205 1.2376282490549504 1.1844076556619751 1.249350355552741 1.0 15.84671532896012 -7.011618132528065 3.6595372469436698 1.180265631357666 0.7779432006121305 0.7959373853629921 0.09538230744652225 0.10143527357666426 2.937590038823185 0.037404213730506154 0.03034639788637394 9.736029193841547e-08 7.011618132528065 -0.40232243074553553 HLFS(ph)STENLAAGSWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HLFSSTENLAAGSWK 15 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 HLFS(0.388)S(0.306)T(0.306)ENLAAGSWK 78.814 0.0065236999999999995 31003000.0 25948.0 34519.0 40370.0 31677.0 42260.0 30085.0 31138.0 22981.0 25345.0 28435.0 True False 30340.483903639157 37945.81819187648 41332.573904077595 29902.24038821965 33979.45636594832 28507.289638384354 28188.383220402273 22377.773100382223 25715.622676970783 33590.040408663845 0.9032583329615009 1.1296746812513259 1.2305008687461039 0.890211503898846 1.011593197047302 0.848682802746242 0.8391887261061964 0.6662026251867904 0.7655728413574037 1.0 15.035745910678392 -6.639165007523101 1.2727235988368462 0.7875201975240416 1.0717003957075808 0.4235478569267269 0.1213576005694427 0.37771747995913946 1.2847379012900872 0.05589879282177853 0.05643355422415454 2.2952764062371187e-07 6.639165007523101 0.28418019818353923 HLFS(ph)STENLAAGSWK ddPTM_PC-9_Lapatinib_30min_R1 1 HLFSSTENLAAGSWK 15 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 HLFS(0.807)S(0.153)T(0.04)ENLAAGSWK 101.54 0.00093712 27639000.0 51412.0 63900.0 73290.0 58865.0 88978.0 76326.0 72331.0 74633.0 73530.0 59233.0 True False 50678.85545219392 63752.043476004284 67264.37910758123 63194.12846788356 83744.48897747857 73061.71490459617 76075.94526169894 78100.72164116168 65248.27709477355 69471.34512698872 0.7294929349583854 0.9176739468549234 0.968231995287074 0.9096430816528621 1.2054536848883457 1.0516813050192784 1.0950694149168623 1.1242149046977437 0.9392113680180555 1.0 16.084130411085855 -4.369759806886975 0.744332864185681 1.0678110380616326 0.32316944848288714 0.600397976246066 0.0804132388853731 3.170552539936422 0.8721213075663979 0.0314236792142261 2.270668477707393 4.2681551029123175e-05 4.369759806886975 -0.7446415895787455 HLFS(ph)STENLAAGSWKEPAEGGGLSSDR ddPTM_PC-9_AZD4547_30min_R2 2 HLFSSTENLAAGSWKEPAEGGGLSSDR 27 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 HLFS(0.333)S(0.333)T(0.333)ENLAAGSWKEPAEGGGLSSDR;HLFS(0.371)S(0.314)T(0.314)ENLAAGSWKEPAEGGGLSSDR 84.32700000000001 4.1005000000000005e-07 61452700.0 29756.0 23562.0 52002.0 72975.0 63414.0 50324.0 43242.0 61958.0 48807.0 58531.0 True False 39217.789036750924 31177.955719977013 51312.41950249683 56151.74120251093 54610.06070531773 47177.23232463224 47090.45422914611 52383.81475320103 51386.838378534645 56481.84750544987 0.6943432406839533 0.5519995732605717 0.9084762940437766 0.994155532838987 0.96686038288759 0.835263618458659 0.8337272293474891 0.9274451362120649 0.9097938656056954 1.0 15.78549965908202 -5.271294051092195 24.59237049928823 0.9173078038851843 0.6231714091406293 0.7840999925578064 0.06267701120725587 214.33852333908698 534883.6689767046 0.017006200207377375 0.03612170230294307 5.354340043514829e-06 5.271294051092195 -0.294136394744555 HLFS(ph)STENLAAGSWKEPAEGGGLSSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HLFSSTENLAAGSWKEPAEGGGLSSDR 27 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 HLFS(0.366)S(0.317)T(0.317)ENLAAGSWKEPAEGGGLSSDR 60.8 0.00075564 29915000.0 66118.0 50614.0 95793.0 122300.0 136370.0 134500.0 128650.0 101560.0 104560.0 93713.0 True False 77310.47150997419 55638.62342372713 98077.06841697541 115447.92750194955 109649.27744023589 127446.5832262822 116463.34065465823 98894.15761171503 106088.99219191402 110702.42506830004 0.6983629442830721 0.5025962474570885 0.885952302819607 1.0428671949211743 0.9904866796963626 1.1512537611317142 1.0520396511892478 0.8933332539978264 0.958325819208209 1.0 16.75632730085338 -5.435810132073376 3.966547364204557 1.0127667596050147 0.6038605417749822 0.813575301388823 0.07771896932810178 0.09152811970611041 2.6113233482564646 0.021911242730533118 0.04796584493677641 3.6659781143701718e-06 5.435810132073376 -0.40890621783003256 HLFS(ph)STENLAAGSWKEPAEGGGLSSDR ddPTM_PC-9_Lapatinib_30min_R1 1 HLFSSTENLAAGSWKEPAEGGGLSSDR 27 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 HLFS(0.362)S(0.319)T(0.319)ENLAAGSWKEPAEGGGLSSDR 57.238 0.0013716 30626000.0 140830.0 85203.0 151550.0 112980.0 107570.0 107510.0 85988.0 70422.0 156240.0 76203.0 True False 138821.7383749412 85005.71768835692 139090.1439999178 121288.92609023153 101242.94409075694 102912.04791805056 90440.03789748467 73694.0632081505 138642.60591986132 89374.58701588491 1.5532573968735413 0.9511173201085505 1.5562605506103961 1.3570851641381498 1.132793420044141 1.151468793917443 1.0119211838305937 0.8245527690668104 1.5512531083944454 1.0 16.447577049905334 -6.326654509550198 4.3423206236730305 1.096444441111709 1.3403338382319891 0.20421878186751274 0.23332437363246847 0.3722798446768886 14.01853115216731 0.07143360478733268 0.08280874900051946 4.713521478951889e-07 6.326654509550198 0.24388939712028024 HLFSS(ph)TENLAAGSWK ddPTM_PC-9_AZD4547_30min_R2 1 HLFSSTENLAAGSWK 15 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 HLFS(0.043)S(0.907)T(0.05)ENLAAGSWK 118.16 0.00011722 16041000.0 19007.0 20407.0 34637.0 32202.0 26823.0 30076.0 27223.0 38574.0 34122.0 23864.0 True False 25050.830629840184 27003.163669364683 34177.69074858623 24778.326415940493 23099.089448682294 28195.34296549638 29645.79426206105 32613.274642337987 35925.61925855636 23028.528623636295 1.0878172478691588 1.1725961354582097 1.4841456572047997 1.07598391633707 1.003064061373577 1.2243658040990473 1.2873507789652199 1.4162118290468626 1.5600484010811961 1.0 14.491134614596978 -7.355823772779324 2.9099696553860332 1.362810822684857 1.174823794628929 0.12306969982703997 0.1784503257434643 0.49200745497352216 8.073640721346473 0.08503247151671058 0.05388645072245875 4.407336673283184e-08 7.355823772779324 -0.18798702805592793 HLFSS(ph)TENLAAGSWKEPAEGGGLSSDR ddPTM_PC-9_AZD4547_30min_R2 3 HLFSSTENLAAGSWKEPAEGGGLSSDR 27 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 HLFS(0.185)S(0.665)T(0.15)ENLAAGSWKEPAEGGGLSSDR;HLFS(0.276)S(0.362)T(0.362)ENLAAGSWKEPAEGGGLSSDR;HLFS(0.134)S(0.431)T(0.431)ENLAAGS(0.003)WKEPAEGGGLSSDR 88.684 2.4993e-07 61394700.0 36987.9 32239.8 68133.9 100841.8 91354.0 68840.5 56634.9 84636.3 68354.2 73534.0 True False 48749.28280388621 42660.68486634899 67230.39996810052 77594.2810002791 78671.07398482357 64535.89265248874 61675.296383660905 71557.70458369127 71967.26346413502 70959.5970420075 0.6870005585717607 0.6011968309387976 0.9474461915038874 1.0934994593380218 1.108674192981267 0.9094737758204013 0.8691607471664422 1.00842884636633 1.014200565732229 1.0 16.114710196584873 -5.318696040219718 5.081701447767025 0.9969157357740032 0.6435164736831671 0.7939999650736251 0.07147783757259761 0.0875937293774155 4.833758531514213 0.020894182422745624 0.04619581712380688 4.800693283697506e-06 5.318696040219718 -0.35339926209083605 HLFSS(ph)TENLAAGSWKEPAEGGGLSSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HLFSSTENLAAGSWKEPAEGGGLSSDR 27 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 HLFS(0.133)S(0.599)T(0.268)ENLAAGSWKEPAEGGGLSSDR;HLFS(0.031)S(0.485)T(0.485)ENLAAGSWKEPAEGGGLSSDR;HLFS(0.192)S(0.616)T(0.192)ENLAAGSWKEPAEGGGLSSDR;HLFS(0.174)S(0.695)T(0.131)ENLAAGSWKEPAEGGGLSSDR 131.35 1.1736e-10 86821000.0 53051.3 42839.5 74145.40000000001 84772.59999999999 108404.0 91758.4 76474.4 90719.3 82528.1 74196.5 True False 62031.837279063184 47092.3224436077 75913.3075339955 80023.06605847753 87163.01438462529 86946.42797256862 69230.19120529025 88338.01450004391 83734.91733467391 87647.73811082906 0.707740309289271 0.5372907899124593 0.8661182726473149 0.913007771601473 0.99446963793189 0.9919985369460004 0.789868543073523 1.0078755756177302 0.9553574243843298 1.0 16.41942923997641 -5.414364923067393 3.9854845531056484 0.9448526893286167 0.6244173411925499 0.7592526983769958 0.07252400607471055 0.1032069788746362 2.8265552202884927 0.019189274047549172 0.04247212840068384 3.851545891930259e-06 5.414364923067393 -0.3204353481360668 HLFSS(ph)TENLAAGSWKEPAEGGGLSSDR ddPTM_PC-9_Lapatinib_30min_R1 5 HLFSSTENLAAGSWKEPAEGGGLSSDR 27 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 HLFS(0.032)S(0.826)T(0.142)ENLAAGSWKEPAEGGGLSSDR;HLFS(0.144)S(0.428)T(0.428)ENLAAGSWKEPAEGGGLSSDR;HLFS(0.203)S(0.617)T(0.179)ENLAAGS(0.001)WKEPAEGGGLSSDR;HLFS(0.134)S(0.431)T(0.431)ENLAAGS(0.004)WKEPAEGGGLSSDR;HLFS(0.168)S(0.69)T(0.142)ENLAAGSWKEPAEGGGLSSDR 121.35 1.3322e-12 71811100.0 80953.9 67125.7 75206.5 64151.2 67513.1 72763.2 52166.200000000004 50839.5 83272.1 51722.9 True False 79799.4825408731 66970.27456584065 69023.31187548529 68869.09325012972 63542.11219386152 69651.2875553037 54867.11058482304 53201.68876871952 73893.11920391253 60663.13434856794 1.3154526781018019 1.1039699033853434 1.1378131482438758 1.1352709349703343 1.0474584420374833 1.1481649984501328 0.9044555836755619 0.8770019772309282 1.2180893716985612 1.0 15.888532420741242 -1.5228787453745058 0.3603254104078995 1.0047797428734826 4.436883452553529 0.39062173674259326 0.10022444979766892 67.14261631246895 0.9368916644744052 0.08258149868654993 158.0945029359584 0.029999999993495084 1.5228787453745058 3.432103709680046 HLFSST(ph)ENLAAGSWKEPAEGGGLSSDR ddPTM_PC-9_AZD4547_30min_R2 1 HLFSSTENLAAGSWKEPAEGGGLSSDR 27 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 HLFS(0.081)S(0.232)T(0.684)ENLAAGS(0.003)WKEPAEGGGLSSDR 54.943000000000005 0.0030250999999999998 6838500.0 2662.1 2382.5 4863.1 10884.0 6575.3 6072.7 4684.6 8074.4 5668.3 5456.1 True False 3508.59242488018 3152.5965326731707 4798.612116506905 8374.86195612373 5662.433092939662 5692.973109009504 5101.520324727297 6826.68701125353 5967.914765936202 5265.08359970759 0.6663887397865892 0.598774259320072 0.9114028344722596 1.590641781374345 1.0754687908951985 1.081269271645692 0.9689343441784329 1.2965961284323515 1.1334890800722794 1.0 12.362240723401404 -5.523445370833538 24.99966565798278 1.1678273790471967 0.6632081809176992 0.6143739281256035 0.16865386383283196 11.814730977056616 521265.8064445791 0.04617933284202307 0.08093771344379004 2.9960884416106086e-06 5.523445370833538 -0.5046191981294975 HLLAPGPQDIY(ph)DVPPVR ddPTM_PC-9_AZD4547_30min_R2 2 HLLAPGPQDIYDVPPVR 17 0 P56945-6;A0A2R8Y6M6;A0A2R8Y5C9;A0A2R8Y8C4;A0A2R8YFS8;A0A2R8Y5E4;A0A2R8Y4C2;A0A2R8YFK2;A0A2R8Y596;P56945;P56945-8;P56945-2;P56945-3;P56945-5;P56945-7;P56945-4;H3BN62 P56945-6 BCAR1 Breast cancer anti-estrogen resistance protein 1 1 HLLAPGPQDIY(1)DVPPVR;HLLAPGPQDIY(1)DVPPVR 138.01 2.756e-07 0.0 30971.0 20915.0 23771.8 29018.0 25726.6 26439.6 21620.7 24900.2 16930.9 24210.8 True False 40819.13376318096 27675.36473488326 23456.5703997818 22328.348423630876 22154.905663440684 24786.327632349297 23544.90041515424 21052.446239672954 17825.832808882584 23363.187261193998 1.747156041118632 1.1845714553190156 1.0039970205068256 0.9557064356847416 0.948282672897107 1.0609137937921305 1.0077777553177458 0.9010947866107653 0.7629880550797579 1.0 14.511949483059013 -4.515385786654669 1.4508956700122488 0.9500989998338276 2.573300277970043 0.910666179072926 0.07525293852742959 0.6526344143981286 0.7745671466247822 0.02288568079641773 1.8462305300175608 3.0522086115727325e-05 4.515385786654669 1.6232012781362155 HLLAPGPQDIY(ph)DVPPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HLLAPGPQDIYDVPPVR 17 0 P56945-6;A0A2R8Y6M6;A0A2R8Y5C9;A0A2R8Y8C4;A0A2R8YFS8;A0A2R8Y5E4;A0A2R8Y4C2;A0A2R8YFK2;A0A2R8Y596;P56945;P56945-8;P56945-2;P56945-3;P56945-5;P56945-7;P56945-4;H3BN62 P56945-6 BCAR1 Breast cancer anti-estrogen resistance protein 1 1 HLLAPGPQDIY(1)DVPPVR 105.53 0.0012462999999999999 3040500.0 15111.0 12298.0 7218.9 8961.4 10521.0 10445.0 11762.0 7981.9 8576.5 5689.6 True False 17668.99384414564 13518.864165349432 7391.025953830708 8459.3218112508 8459.485575630444 9897.245812628382 10647.818210494306 7772.383582522124 8701.915087356088 6721.079441151181 2.628892278220016 2.011412643418173 1.099678410074674 1.2586254760592288 1.258649841844677 1.4725678961671653 1.584242278896581 1.1564189429058254 1.2947198680731011 1.0 12.714477240781205 -5.00863314008027 2.950687629098044 1.2907216438936486 2.619123366725421 0.8734616268539264 0.16780270914802672 0.09252229003566671 1.5144405576168007 0.04552263779357199 0.22688525079572255 9.803177358067563e-06 5.00863314008027 1.3284017228317722 up HLLAPGPQDIY(ph)DVPPVR ddPTM_PC-9_Lapatinib_30min_R1 1 HLLAPGPQDIYDVPPVR 17 0 P56945-6;A0A2R8Y6M6;A0A2R8Y5C9;A0A2R8Y8C4;A0A2R8YFS8;A0A2R8Y5E4;A0A2R8Y4C2;A0A2R8YFK2;A0A2R8Y596;P56945;P56945-8;P56945-2;P56945-3;P56945-5;P56945-7;P56945-4;H3BN62 P56945-6 BCAR1 Breast cancer anti-estrogen resistance protein 1 1 HLLAPGPQDIY(1)DVPPVR 85.619 0.0055744 4036100.0 14573.0 11308.0 12966.0 11719.0 7896.0 11467.0 10122.0 8692.1 10423.0 9053.0 True False 14365.186347639099 11281.81702076145 11899.985530207397 12580.854353437991 7431.572804133284 10976.583140882578 10646.067632673634 9095.966698071126 9249.051980944165 10617.79898763575 1.352934479581608 1.0625381996682117 1.1207582234382787 1.18488345542124 0.6999165093243173 1.0337908217762106 1.002662382766033 0.8566715859532873 0.8710893841289077 1.0 13.374197113796916 -6.225256679159007 24.970917330830794 0.9142758159078435 1.167617180286286 0.5748839346499119 0.11333838252535203 450.81366666792735 311121.8174369892 0.03293835731098493 0.04252192888355524 5.953101959653851e-07 6.225256679159007 0.25334136437844257 HLLDEK ddPTM_PC-9_Lapatinib_30min_R1 1 HLLDEK 6 0 Q53F19;Q53F19-2 Q53F19 C17orf85 Uncharacterized protein C17orf85 0 116.0 0.019144 15155000.0 132220.0 121140.0 125530.0 120830.0 115810.0 113480.0 114690.0 104980.0 106310.0 100090.0 False True 130334.51855382154 120859.5077728196 115209.40795981302 129716.24127706372 108998.28349122024 108626.72493480032 120628.08701752008 109857.75404833173 94336.24830607051 117390.4231384582 1.110265344218891 1.0295516835327336 0.9814208423452675 1.1049984982511531 0.9285108663647996 0.9253457141616964 1.0275803067448115 0.9358323371810158 0.8036111105486345 1.0 16.84095519077045 -6.064769110189097 0.5689011295135732 0.9194780017012165 1.090705487732168 0.38326551913767326 0.06855077421824361 1.3665369517999448 0.8345479504183421 0.049590003755905866 0.13052659271176126 8.614516155612425e-07 6.064769110189097 0.1712274860309515 HLLGAEHGDEPR ddPTM_PC-9_AZD4547_30min_R2 2 HLLGAEHGDEPR 12 0 U3KQC1;K7EIR0;A0A0A0MQU0;Q9BV38 U3KQC1 WDR18 WD repeat-containing protein 18 0 ; 103.43 0.00088202 5560000.0 8815.2 8563.6 16613.8 16908.1 17843.0 13788.8 7722.4 16604.699999999997 12871.5 14463.599999999999 False True 11618.250232449478 11331.6162296747 16393.490156735923 13010.19877254094 15365.80744259919 12926.584156225437 8409.678639728912 14038.82515304686 13551.861212311947 13957.233766377214 0.8324178291286978 0.811881238026722 1.1745515215362816 0.9321473717723587 1.1009206910050624 0.9261565989791904 0.602531904279465 1.00584581357849 0.9709560962544166 1.0 13.768725416585415 -7.000223329212391 24.99999974111793 0.8766097012985707 0.975070670232922 0.04896640893535387 0.14845904848327227 22.16987755882764 2482022.4641960626 0.054161033785502626 0.04727281857135718 9.994858976806264e-08 7.000223329212391 0.0984609689343513 HLLGAEHGDEPR ddPTM_PC-9_Lapatinib_30min_R1 2 HLLGAEHGDEPR 12 0 U3KQC1;K7EIR0;A0A0A0MQU0;Q9BV38 U3KQC1 WDR18 WD repeat-containing protein 18 0 ; 100.69 0.0012431 4452000.0 11295.4 10539.2 12684.0 11316.2 9885.6 7490.9 8848.2 10908.7 8540.3 6635.700000000001 False True 11134.325524677326 10514.797129926515 11641.170481655905 12148.431097736577 9304.148443837385 7170.531669140779 9306.316501424899 11415.558026167264 7578.401480654079 7782.671903485536 1.4306559061921553 1.3510523455598038 1.4957807069372033 1.5609589159599286 1.1954953978813423 0.9213457483578866 1.1957739728507617 1.466791632453979 0.9737531755977054 1.0 12.926049822924755 -6.372915688391122 5.663090563022873 1.13767673064988 1.4531711905594737 0.539735502725553 0.15152628698179965 0.2046881112123604 8.936850418527747 0.04914652633544435 0.05580066186153353 4.2372521781377754e-07 6.372915688391122 0.3154944599095937 HLLNS(ph)PTDPFNR ddPTM_PC-9_AZD4547_30min_R2 1 HLLNSPTDPFNR 12 0 O95155-2;O95155;O95155-4;O95155-3 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 HLLNS(0.998)PT(0.002)DPFNR 108.36 0.00081705 4001300.0 20031.0 17612.0 23268.0 30657.0 24129.0 24819.0 21631.0 25100.0 17845.0 22518.0 True False 26400.441329317026 23304.734578568685 22959.45111695888 23589.502295928436 20779.104846857343 23267.06400653858 23556.117095200472 21221.3717406202 18788.250268710457 21729.65167394578 1.2149500473112325 1.0724854189223592 1.0565954512969782 1.085590448014988 0.9562557724646751 1.0707518167185435 1.0840540588805045 0.9766089240199365 0.8646365137660208 1.0 14.407377427869898 -1.5228787452803376 0.32340024916100324 0.9738313597321988 3.0542493039307215 0.5408852819558048 0.06070087593536126 50.02801351518865 0.7135451330912461 0.05940260838503136 61.77954801388163 0.029999999999999995 1.5228787452803376 2.0804179441985227 HLLNS(ph)PTDPFNR ddPTM_PC-9_Lapatinib_30min_R1 1 HLLNSPTDPFNR 12 0 O95155-2;O95155;O95155-4;O95155-3 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 HLLNS(0.998)PT(0.002)DPFNR 98.676 0.0020311 3349500.0 22408.0 20243.0 20879.0 18887.0 20563.0 20098.0 18201.0 16839.0 22067.0 14029.0 True False 22088.45781087606 20196.12857722622 19162.409215270716 20276.01298518501 19353.524768413477 19238.455390726267 19143.35872182302 17621.401413791784 19581.58208418832 16453.89395753252 1.3424456160885894 1.2274376284028816 1.1646124172629817 1.2322926741546636 1.176227634526204 1.1692341910298374 1.1634546066257632 1.0709563012422834 1.1900880201810198 1.0 14.006141430283174 -1.5228787486452802 0.07439076213291501 0.8403583370172462 1.996843641714448 0.7293259378137259 0.045357402255156234 117.22254252628171 0.6428934020258117 1.6382678568919506 14.063575695914322 0.029999999767558 1.5228787486452802 1.1564853046972017 HLLS(ph)PQLVQYQCGDSGK ddPTM_PC-9_AZD4547_30min_R2 3 HLLSPQLVQYQCGDSGK 17 0 Q9P209 Q9P209 CEP72 Centrosomal protein of 72 kDa 1 HLLS(1)PQLVQYQCGDSGK;HLLS(1)PQLVQYQCGDSGK;HLLS(1)PQLVQYQCGDSGK 150.01 3.2415e-05 14435100.0 74387.0 76291.0 88631.0 121361.0 95419.0 90787.0 83529.0 113197.0 85489.0 91426.0 True False 98040.51865428116 100950.5737981821 87455.69502953347 93383.09645875891 82171.71890183123 85110.07453812074 90962.91918288551 95705.00465828637 90007.77401074753 88225.20356790868 1.1112529604855763 1.144237357531042 0.9912779057768576 1.0584628052105325 0.9313859937833074 0.9646911664262676 1.031030992327148 1.0847807745166644 1.0202047756281658 1.0 16.42890323338498 -5.260391749713347 24.9981543953602 1.0112805333169317 1.1277451677522716 0.5548085526874877 0.04209896050486429 70.501793696903 1682234.650804209 0.011790864499669871 0.027903859836202104 5.49045391134324e-06 5.260391749713347 0.11646463443533994 HLLS(ph)PQLVQYQCGDSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HLLSPQLVQYQCGDSGK 17 0 Q9P209 Q9P209 CEP72 Centrosomal protein of 72 kDa 1 HLLS(1)PQLVQYQCGDSGK;HLLS(1)PQLVQYQCGDSGK 110.33 0.0012304 0.0 27816.0 28827.0 29959.0 34361.0 37700.0 34169.0 32102.0 31300.0 34721.0 27752.0 True False 32524.699408957404 31688.75404899399 30673.336180140184 32435.86456986505 30312.95563171443 32377.117488913264 29061.066161646664 30478.40816509132 35228.72893932147 32783.217915288864 0.9921143035134785 0.9666151178592979 0.9356414083388468 0.9894045378241585 0.9246485720237245 0.9876125514150272 0.8864616718450227 0.9296954388018552 1.0745964301110327 1.0 15.00066985212518 -8.254890208549511 24.997905901230098 1.0372982172518033 0.9508988210007908 0.47356484347566763 0.03616934692955181 390.0489299639414 1488816.071534558 0.025226799208515536 0.009036481073280915 5.560448099430665e-09 8.254890208549511 -0.08639939625101245 HLLS(ph)PQLVQYQCGDSGK ddPTM_PC-9_Lapatinib_30min_R1 2 HLLSPQLVQYQCGDSGK 17 0 Q9P209 Q9P209 CEP72 Centrosomal protein of 72 kDa 1 HLLS(1)PQLVQYQCGDSGK;HLLS(1)PQLVQYQCGDSGK 150.94 1.3342999999999999e-05 10240000.0 94661.0 85026.0 85857.0 92541.0 84496.0 90439.0 79685.0 78794.0 86104.0 62108.0 True False 93311.11678129855 84829.12752098203 78798.16887760405 99346.77384772609 79526.11140552758 86571.13479360596 83810.69939830044 82455.05689163908 76406.06080468351 72843.28504629195 1.2809844685340492 1.164542860293479 1.0817492487815148 1.3638425804738372 1.0917425175839983 1.1884573126897005 1.150561775804574 1.13195137807471 1.0489101467091637 1.0 16.152508365196535 -8.175336852828563 0.7335843079109857 0.995511351192432 1.2002244267529212 0.43195669611050824 0.07747684862539364 0.6262199696479842 0.729820542541575 0.07225594632301424 0.030135469008614756 6.678257294252923e-09 8.175336852828563 0.20471307556048923 HLLS(ph)PVGR ddPTM_PC-9_AZD4547_30min_R2 2 HLLSPVGR 8 0 Q9NXE4-3;Q9NXE4-6;Q9NXE4-2;Q9NXE4;Q9NXE4-4;H7C0W5;H7C1Q6;Q9NXE4-5;Q9NXE4-9;Q9NXE4-10;Q9NXE4-7;Q9NXE4-8 Q9NXE4-3 SMPD4 Sphingomyelin phosphodiesterase 4 1 HLLS(1)PVGR;HLLS(1)PVGR 70.1 0.028486 2293300.0 10718.400000000001 11188.6 16036.2 13569.5 14855.0 11119.0 12041.8 15950.800000000001 13415.3 11259.2 True False 14126.62824343026 14805.096145001895 15823.54951013305 10441.261421685133 12792.63966596485 10423.727172275378 13113.496871942365 13485.970372919703 14124.405370122231 10865.018835033756 1.3001936267132455 1.362638792421007 1.456375709088579 0.9609980047174665 1.177415323452139 0.9593841787613425 1.2069465383399516 1.2412284394238515 1.2999890367956595 1.0 13.407403055052193 -5.7487256427155495 24.99998218534971 1.1301191131743973 1.3720263401057744 0.49368440224067844 0.11678476981384152 207.04760487165495 407129.8277558829 0.032611499533362606 0.056008750665020965 1.783505107091712e-06 5.7487256427155495 0.24190722693137712 HLLS(ph)PVGR ddPTM_PC-9_Lapatinib_30min_R1 1 HLLSPVGR 8 0 Q9NXE4-3;Q9NXE4-6;Q9NXE4-2;Q9NXE4;Q9NXE4-4;H7C0W5;H7C1Q6;Q9NXE4-5;Q9NXE4-9;Q9NXE4-10;Q9NXE4-7;Q9NXE4-8 Q9NXE4-3 SMPD4 Sphingomyelin phosphodiesterase 4 1 HLLS(1)PVGR 70.056 0.028551999999999998 0.0 7352.1 8488.8 6612.0 4807.1 4221.6 5764.5 4850.3 4063.4 6621.0 2413.6 True False 7247.257705789989 8469.144705150318 6068.386883058097 5160.630170015509 3973.2937879849396 5517.96577270582 5101.4248012998305 4252.200398171007 5875.273257779076 2830.787544080155 2.5601559964984713 2.9917980679480167 2.143709758702495 1.8230369074527 1.4036001381643899 1.949268776544248 1.8021221027230088 1.5021262924034555 2.075490712846204 1.0 11.466987760997332 -1.522878745309342 0.2836709306192926 1.4295972773050765 12.967135216518313 0.6206882909873198 0.33418964008728264 34.634216572866706 0.4895233474694496 0.369193693465488 198.93242097144193 0.029999999997996445 1.522878745309342 11.537537939213237 HLMQDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HLMQDLR 7 0 Q8TDN6 Q8TDN6 BRIX1 Ribosome biogenesis protein BRX1 homolog 0 99.375 0.008048399999999999 1265900.0 8069.8 5935.4 7940.4 8809.5 9386.4 10281.0 9722.8 7524.2 10169.0 4717.9 False True 9435.857754184806 6524.6272863079375 8129.729250134688 8315.932275784353 7547.202300836187 9741.846261333874 8801.785997023806 7326.697722548881 10317.702387142084 5573.217923124148 1.6930717377897542 1.1707109566335534 1.4587136843156945 1.492124009951281 1.354191134267632 1.7479751188112418 1.579300525914091 1.3146260963794854 1.8513007259831582 1.0 12.444294851224289 -10.680569657724934 4.80289157361341 0.9999547018449634 1.503049514601667 0.37840633737751395 0.19833967616548953 9.264335689962017e-05 1.6247725316647806e-05 0.18492866029339147 0.04484776100114798 2.0865574282039142e-11 10.680569657724934 0.5030948127567035 HLNEIDLFHCIDPNDSK ddPTM_PC-9_AZD4547_30min_R2 2 HLNEIDLFHCIDPNDSK 17 0 A0A087WYT3;Q15185-4;Q15185;Q15185-3 A0A087WYT3 PTGES3 Prostaglandin E synthase 3 0 ; 116.78 5.6826e-05 13934000.0 57191.0 51159.0 67445.0 84087.0 83249.0 74283.0 61345.0 63406.0 67162.0 73191.0 False True 75376.54835330091 67695.14628122847 66550.63523221991 64702.04128119953 71691.31333233972 69638.07226712206 66804.5861589882 53608.059624930815 70712.04620605944 70628.60536760667 1.0672240795493868 0.9584664163887965 0.9422617774460956 0.9160883319787974 1.015046424309271 0.9859754685041692 0.9458573592283852 0.7590134244604211 1.0011814028893602 1.0 16.107964988877285 -7.530834442265123 24.996109579614377 0.8985455433195001 0.9757868155516176 0.0984927329868871 0.07435729336635274 323.4338552541016 1016184.1915127799 0.03342429724877063 0.0193422800607668 2.9455442930152277e-08 7.530834442265123 0.07724127223211752 HLNEIDLFHCIDPNDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HLNEIDLFHCIDPNDSK 17 0 A0A087WYT3;Q15185-4;Q15185;Q15185-3 A0A087WYT3 PTGES3 Prostaglandin E synthase 3 0 ; 137.27 2.4479e-05 7696600.0 50461.0 40050.0 49095.0 63511.0 61194.0 52264.0 59872.0 61435.0 50789.0 41963.0 False True 59003.05064982026 44025.89931877091 50265.610993824346 59952.68457544016 49203.47498480457 49523.18383448629 54200.49072425736 59822.39634576309 51531.69304165197 49570.559721074744 1.1902841319892405 0.888146100558422 1.0140214529886395 1.2094413481062933 0.9925947026151066 0.9990442737210347 1.0934008215609117 1.2068130092210723 1.039562460694658 1.0 15.597195928498094 -7.493652549112229 22.694946093139787 1.1039339685801421 1.0448851686012295 0.015927046279531676 0.10203187614294569 659.6322795575418 512225.0322035253 0.04242610419417995 0.02852319631755801 3.208835479307354e-08 7.493652549112229 -0.05904879997891266 HLNEIDLFHCIDPNDSK ddPTM_PC-9_Lapatinib_30min_R1 2 HLNEIDLFHCIDPNDSK 17 0 A0A087WYT3;Q15185-4;Q15185;Q15185-3 A0A087WYT3 PTGES3 Prostaglandin E synthase 3 0 ; 130.47 1.1811e-05 5633100.0 29733.0 26362.0 31337.0 26604.0 26850.0 25759.0 30724.0 24318.0 30277.0 27876.0 False True 29309.001967635595 26300.960408676456 28760.592824318126 28560.546908342356 25270.73578913105 24657.347617161806 32314.738386313435 25447.90305722364 26866.885429055605 32694.329457564814 0.896455209631286 0.8044502164454375 0.879681379049158 0.8735627058940649 0.772939412075445 0.7541781105853691 0.9883896970040611 0.7783583110414735 0.8217597936647434 1.0 14.996752814267957 -10.451053042097962 4.8297469438341745 1.000000980626373 0.8400260099448873 0.33466078657139775 0.06720562979274362 21289127.127627924 23033692.567255717 191.62042221360215 0.015979927870599157 3.5395410863210676e-11 10.451053042097962 -0.1599749706814857 HLNSS(ph)QPSGFGPANSLEDVVR ddPTM_PC-9_AZD4547_30min_R2 2 HLNSSQPSGFGPANSLEDVVR 21 0 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 HLNS(0.168)S(0.821)QPS(0.011)GFGPANSLEDVVR;HLNS(0.366)S(0.634)QPSGFGPANSLEDVVR 130.57 1.443e-05 6095700.0 7996.7 9363.9 20193.7 29475.0 23955.7 25297.0 18792.1 30317.0 21918.8 22594.5 True False 10539.484258307091 12390.59755395521 19925.918343670826 22679.994134210494 20629.8645604816 23715.174590974915 20464.56049487852 25632.204265353867 23077.383019882916 21803.473432230556 0.48338556198698623 0.5682854886615933 0.913887340271928 1.0402009663599856 0.9461733069551161 1.0876787436958748 0.9385917596334529 1.1756018757756077 1.0584269103549908 1.0 14.412270363371942 -5.287970938622305 2.15194408433246 1.0385170385221063 0.4740493081657186 0.9063602700522723 0.06483048932979389 0.09153723877456214 0.7843829530550833 0.018155258468522385 0.0645572251393734 5.152631229273308e-06 5.287970938622305 -0.5644677303563876 down HLNSSQPSGFGPANS(ph)LEDVVR ddPTM_PC-9_AZD4547_30min_R2 4 HLNSSQPSGFGPANSLEDVVR 21 0 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 HLNSSQPSGFGPANS(1)LEDVVR;HLNSSQPSGFGPANS(1)LEDVVR;HLNSSQPSGFGPANS(1)LEDVVR;HLNSSQPSGFGPANS(1)LEDVVR 217.41 2.6394999999999996e-32 59463700.0 28007.1 49342.1 180669.0 199829.0 182733.0 212956.0 120626.8 239930.0 161894.0 181724.0 True False 36912.77521613075 65290.96888764441 178273.21101297243 153761.51137727406 157363.67715117853 199639.82765528184 131362.3515149247 202854.33154290865 170451.38632684865 175361.89807248054 0.21049484307517002 0.3723212944505104 1.0166017417266353 0.8768239456083065 0.8973652707963791 1.1384447240230415 0.7490928928051979 1.156775410009904 0.9719978410384091 1.0 17.41997579329574 -5.192691140365502 3.939087096811276 0.9744141064753248 0.24723012939679834 0.8489842997479912 0.11603222726878158 0.07536812215793293 2.281960111260932 0.029022769033771274 0.08580587197184587 6.416657513752067e-06 5.192691140365502 -0.7271839770785264 down HLNSSQPSGFGPANS(ph)LEDVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HLNSSQPSGFGPANSLEDVVR 21 0 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 HLNSSQPSGFGPANS(1)LEDVVR;HLNSSQPSGFGPANS(1)LEDVVR;HLNSSQPSGFGPANS(1)LEDVVR;HLNSSQPSGFGPANS(1)LEDVVR 201.29 8.8572e-20 35745800.0 31664.500000000004 41368.5 101383.0 100231.0 114400.0 95966.0 91921.0 69804.5 79793.0 67978.0 True False 37024.67444761764 45475.291285108025 103800.35521716837 94615.3820232865 91984.14122727151 90933.37402151215 83213.5774295907 67972.20583898126 80959.82167147487 80301.87328644819 0.46106862682449967 0.5663042395398573 1.2926268213805892 1.17824626189952 1.1454793949719082 1.1323941808572746 1.0362594796855618 0.8464585327482305 1.0081934375637749 1.0 16.293146022952634 -5.170829944074698 5.981065497884762 1.0798833473315956 0.49449903403937046 0.7942521246215998 0.11551115249049922 0.10556100029529669 5.603386087594426 0.0330056631447345 0.09044929997764431 6.74792203167584e-06 5.170829944074698 -0.5853843132922252 down HLNSSQPSGFGPANS(ph)LEDVVR ddPTM_PC-9_Lapatinib_30min_R1 4 HLNSSQPSGFGPANSLEDVVR 21 0 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 HLNSSQPSGFGPANS(1)LEDVVR;HLNSSQPSGFGPANS(1)LEDVVR;HLNSSQPSGFGPANS(1)LEDVVR;HLNSSQPSGFGPANS(1)LEDVVR 191.45 6.1109e-16 47087400.0 53632.3 43774.8 149980.0 76954.0 121790.0 145299.0 85753.0 119067.0 166000.0 153964.0 True False 52867.49356704075 43673.442140115694 137649.223339542 82613.45387101843 114626.55164835266 139084.90047851225 90192.87074734847 124599.2874954541 147303.3319425052 180576.47225586546 0.2927706633460579 0.2418556614520256 0.762276622308258 0.45749843730450324 0.6347812105108248 0.7702271438852661 0.49947188368787526 0.690008426562375 0.8157393380339476 1.0 17.462250407283427 -5.99351525822522 0.1846361634820059 1.0488813463872093 2.4928446615550528e-18 0.6431893098622257 0.1364132621778585 7.0705647370262685 0.3998375221661483 0.4800655642021787 1.8776454037275663 1.0150437040483859e-06 5.99351525822522 -1.0488813463872093 HLPS(ph)PPLTQEVDLHSIAGPPVPPR ddPTM_PC-9_AZD4547_30min_R2 4 HLPSPPLTQEVDLHSIAGPPVPPR 24 0 G5E9C8;Q07889 G5E9C8 SOS1 Son of sevenless homolog 1 1 HLPS(0.615)PPLT(0.385)QEVDLHSIAGPPVPPR;HLPS(1)PPLTQEVDLHSIAGPPVPPR;HLPS(0.995)PPLT(0.005)QEVDLHSIAGPPVPPR;HLPS(0.838)PPLT(0.162)QEVDLHSIAGPPVPPR 97.662 2.7823e-06 26423100.0 71049.0 66465.0 83938.0 121124.0 106462.0 99409.0 76554.0 99680.0 82442.0 82228.0 True False 93641.10408899422 87948.51145608495 82824.92727588503 93200.73314714551 91681.5889678862 93192.93951512923 83367.15769525098 84276.74641852661 86799.7158113213 79349.22274825524 1.1801136904148597 1.1083726898637931 1.0438026285229898 1.174563907737771 1.1554188660266635 1.1744656883507834 1.0506360970887278 1.0620992052550347 1.093894972187738 1.0 16.27592847100651 -8.191225989754775 0.7364154759439966 1.0092149539880948 1.1337925036946348 0.4341150607250631 0.04609359287780871 0.6676691106504099 0.787262988336662 0.04690873417097862 0.0194349792669367 6.438341523809781e-09 8.191225989754775 0.12457754970654 HLPS(ph)PPLTQEVDLHSIAGPPVPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HLPSPPLTQEVDLHSIAGPPVPPR 24 0 G5E9C8;Q07889 G5E9C8 SOS1 Son of sevenless homolog 1 1 HLPS(0.961)PPLT(0.039)QEVDLHSIAGPPVPPR;HLPS(0.997)PPLT(0.003)QEVDLHSIAGPPVPPR;HLPS(0.983)PPLT(0.017)QEVDLHSIAGPPVPPR 96.633 4.6855e-06 17668500.0 102330.0 106811.0 129138.0 132418.0 146242.0 141707.0 144256.0 137892.0 126922.0 116997.0 True False 119652.44789037283 117414.49019069257 132217.1396785922 124999.04876494825 117586.92990698108 134275.63545908354 130591.02735700281 134272.48110865068 128777.99413716648 138207.62995225776 0.8657441555991184 0.8495514338191896 0.9566558642548542 0.9044294356840338 0.8507991197562691 0.9715500910150006 0.9448901439241377 0.9715272677422626 0.931771959201177 1.0 17.07647773842949 -6.775073828117244 24.99815915730278 0.9609772521495902 0.8884542631153562 0.5774394961834124 0.03348337889408423 192.74893790472632 353394.5856798153 0.01207568268642414 0.01070598446180477 1.6785186532128772e-07 6.775073828117244 -0.07252298903423393 HLPS(ph)PPLTQEVDLHSIAGPPVPPR ddPTM_PC-9_Lapatinib_30min_R1 4 HLPSPPLTQEVDLHSIAGPPVPPR 24 0 G5E9C8;Q07889 G5E9C8 SOS1 Son of sevenless homolog 1 1 HLPS(0.96)PPLT(0.04)QEVDLHSIAGPPVPPR;HLPS(0.941)PPLT(0.059)QEVDLHSIAGPPVPPR;HLPS(0.986)PPLT(0.014)QEVDLHSIAGPPVPPR;HLPS(0.907)PPLT(0.093)QEVDLHSIAGPPVPPR 115.45 1.1416999999999999e-08 16080000.0 70822.2 57526.899999999994 58776.600000000006 56090.600000000006 56830.700000000004 62030.7 52278.299999999996 55276.5 66557.5 46656.6 True False 69812.2624407993 57393.69999749221 53944.214832237194 60215.68983675644 53488.02995945508 59377.79156162423 54985.01457431357 57844.84798678436 59061.09346845349 54721.13114398831 1.2757825173076474 1.0488397954799498 0.9858022614754288 1.1004101811841251 0.9774657219477325 1.0850980292308432 1.0048223314249647 1.0570842886009901 1.0793105375151217 1.0 15.7398104321226 -4.762722820805656 5.8789518286418865 1.0377263900472242 1.2850086438749886 0.7493244483043553 0.04136902368488987 0.061442750563093354 7.8174964770101045 0.009463344859054383 0.06142871186704672 1.7269397228042157e-05 4.762722820805656 0.24728225382776436 HLPS(ph)PPTLDSIITEYLR ddPTM_PC-9_AZD4547_30min_R2 2 HLPSPPTLDSIITEYLR 17 0 Q9Y4B6-3;Q9Y4B6-2;Q9Y4B6 Q9Y4B6-3 VPRBP Protein VPRBP 1 HLPS(0.995)PPT(0.005)LDSIITEYLR;HLPS(1)PPTLDSIITEYLR 151.28 2.568e-05 108544000.0 173175.0 145944.0 202441.0 292384.0 251426.0 222552.0 177888.0 244839.0 214864.0 205255.0 True False 228241.04773623246 193117.543909529 199756.5000674003 224979.3860877695 216519.83982866936 208635.78825831763 193719.68738528172 207004.7583905058 226221.27238645032 198069.08492475998 1.1523305003551354 0.9750009396109851 1.008519326190058 1.1358632073916626 1.0931531284194007 1.053348574501526 0.9780410075548617 1.0451139230998123 1.1421331727381103 1.0 17.595644193097975 -9.353108796780926 15.633715805752031 0.9999999998709993 1.0599868072456757 0.08392768575438525 0.06243756736741483 0.0 0.0 0.061171335232254334 0.014836228024861866 4.4349752774260795e-10 9.353108796780926 0.05998680737467643 HLPS(ph)PPTLDSIITEYLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HLPSPPTLDSIITEYLR 17 0 Q9Y4B6-3;Q9Y4B6-2;Q9Y4B6 Q9Y4B6-3 VPRBP Protein VPRBP 1 HLPS(1)PPTLDSIITEYLR 151.28 2.568e-05 34993000.0 25764.0 27729.0 32260.0 33433.0 33256.0 29661.0 29047.0 27447.0 31317.0 26981.0 True False 30125.336337804805 30481.75186542319 33029.20074673128 31559.85740124844 26739.725530193497 28105.524944793706 26295.4578779313 26726.545332500344 31774.951879056785 31872.441718521502 0.9451844513154626 0.9563670124372629 1.0362933922171884 0.9901926460472146 0.8389606847929283 0.881812733175733 0.8250217573588239 0.8385471552049051 0.9969412497377612 1.0 14.960021926442595 -6.246679411719968 24.598048921605745 0.8844616197219318 0.9840552186762197 0.29794043140011894 0.06226029398146163 712.3649712154267 1187182.6885779009 0.018222296392305114 0.02341604875761146 5.666574308861657e-07 6.246679411719968 0.09959359895428788 HLPS(ph)PPTLDSIITEYLR ddPTM_PC-9_Lapatinib_30min_R1 1 HLPSPPTLDSIITEYLR 17 0 Q9Y4B6-3;Q9Y4B6-2;Q9Y4B6 Q9Y4B6-3 VPRBP Protein VPRBP 1 HLPS(1)PPTLDSIITEYLR 95.429 0.00093572 34403000.0 4900.3 4027.1 4291.1 3898.6 4694.6 6375.6 3540.7 5013.2 4865.7 3137.5 True False 4830.4208233950385 4017.7754973742863 3938.302322125016 4185.316049348353 4418.4728579387165 6102.9304502495 3724.0201212218444 5246.131573586374 4317.673627907512 3679.8126945440395 1.3126811673205474 1.0918423927748646 1.0702453219872392 1.1373720340586384 1.200733087444877 1.6584894278173867 1.0120134991499297 1.425651795093993 1.1733405980987055 1.0 11.84541661846349 -6.530102494687724 24.999164631863728 1.2836318272533662 1.1460384213411552 0.047305251108603175 0.19068358378920314 412.9191907836083 1428972.6618706903 0.059839431541134004 0.05995546465991529 2.9505128153831075e-07 6.530102494687724 -0.13759340591221103 HLPSPPTLDSIITEYLR ddPTM_PC-9_AZD4547_30min_R2 1 HLPSPPTLDSIITEYLR 17 0 Q9Y4B6-3;Q9Y4B6-2;Q9Y4B6 Q9Y4B6-3 VPRBP Protein VPRBP 0 139.34 6.5842e-05 1490700.0 4977.6 5121.5 7017.4 8739.8 7441.4 6734.2 6141.9 6474.9 4729.6 6125.8 False True 6560.373259488216 6776.924718608872 6924.344690912297 6724.974138563967 6408.290057913893 6313.109409437614 6688.517201563119 5474.3529834000665 4979.597000330233 5911.337606548405 1.1097950575891364 1.146428299256939 1.171366812689181 1.1376400040346604 1.0840676822137478 1.0679663097645002 1.1314727134098679 0.9260768624237837 0.842380748955022 1.0 12.529268902372255 -7.778465574160072 6.903576140313255 0.9114398546732987 1.1214945114236128 0.7995838890888073 0.04543330639029626 0.06491288950598145 13.008337301912608 0.02456187211198332 0.01229786055797743 1.6654608410118656e-08 7.778465574160072 0.2100546567503141 HLPSPPTLDSIITEYLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HLPSPPTLDSIITEYLR 17 0 Q9Y4B6-3;Q9Y4B6-2;Q9Y4B6 Q9Y4B6-3 VPRBP Protein VPRBP 0 115.38 0.00012929 767010.0 5789.1 5987.9 5930.2 7957.9 8421.6 5387.9 6251.5 6464.9 6255.7 5102.1 False True 6769.080290063106 6582.339139347523 6071.59845840874 7512.0446628598975 6771.447934961437 5105.34903914413 5659.312663059441 6295.203225127758 6347.177777878327 6027.070341798622 1.1231128734500633 1.0921291383805545 1.00738802006363 1.2463841031956702 1.1235057085696256 0.8470697618605479 0.9389823483245703 1.04448809589455 1.0531116144206436 1.0 12.557241187213174 -6.712945544523408 24.998929404823492 0.9771514374142735 1.1179702988739495 0.4614273053776953 0.07658183895007367 113.752438526815 58639.78056715187 0.026792237750015973 0.026792181590578893 1.936664783960735e-07 6.712945544523408 0.14081886145967604 HLPSPPTLDSIITEYLR ddPTM_PC-9_Lapatinib_30min_R1 1 HLPSPPTLDSIITEYLR 17 0 Q9Y4B6-3;Q9Y4B6-2;Q9Y4B6 Q9Y4B6-3 VPRBP Protein VPRBP 0 142.4 9.089700000000001e-05 1176600.0 7745.8 5800.9 8602.9 6849.6 6517.1 6588.0 6413.9 5649.7 8231.6 4486.8 False True 7635.343471594251 5787.468372456232 7895.602770154335 7353.342433595769 6133.776991111578 6306.246597378083 6745.980358546271 5912.205687243863 7304.470525409191 5262.337401714801 1.4509414521969222 1.09979044113939 1.500398428953159 1.3973529008610484 1.1655993378746121 1.1983736723766725 1.2819361138546546 1.1234942262191883 1.3880657905038425 1.0 12.361488036429956 -6.262807691592702 24.995660203099458 1.203810569493701 1.3532598979554145 0.2658611660208392 0.13671689998169928 189.27873352471013 3457650.539807952 0.039937329041629166 0.04776509524899971 5.459995797175901e-07 6.262807691592702 0.14944932846171355 HLQQGSES(ph)PMMIGELR ddPTM_PC-9_AZD4547_30min_R2 1 HLQQGSESPMMIGELR 16 0 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 HLQQGS(0.144)ES(0.856)PMMIGELR 57.045 0.030060000000000003 8514500.0 40666.0 48308.0 52014.0 55698.0 46192.0 61563.0 60228.0 63709.0 49904.0 58825.0 True False 53596.942094653576 63922.61628557212 51324.260374656114 42857.68662552184 39779.03813195885 57713.45587793766 65588.17532290386 53864.23793717819 52541.823558964774 56765.55465493647 0.9441807169938866 1.1260810657826146 0.9041444355937924 0.7549945893428319 0.7007601418459771 1.016698528337532 1.1554220816056124 0.948889485262768 0.9255934144985158 1.0 15.792728147260787 -10.610125197975634 6.90688832319984 1.000000028647407 0.9422730502274561 0.01661633529013662 0.1341410349911168 6.574858191395119e-08 8.728457193770108e-09 0.14449125450765182 0.03504425949169109 2.454001376661478e-11 10.610125197975634 -0.05772697841995078 HLQQGSES(ph)PMMIGELR ddPTM_PC-9_Lapatinib_30min_R1 2 HLQQGSESPMMIGELR 16 0 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 HLQQGS(0.01)ES(0.99)PMMIGELR;HLQQGS(0.007)ES(0.993)PMMIGELR 94.176 0.0018277 8170800.0 42832.0 44021.0 61039.0 42788.0 47800.0 52349.0 44534.0 45184.0 54952.0 37906.0 True False 42221.20782557316 43919.07207914218 56020.60903735379 45934.7722565837 44988.49797841578 50110.15530147926 46839.75261346447 47283.4135923017 48762.72708978643 44458.00159342992 0.949687487343396 0.9878777836391236 1.2600793339670178 1.0332172074817692 1.0119325288130867 1.1271346777963276 1.0535730562479113 1.0635523842189372 1.0968267880262226 1.0 15.44015547960024 -5.020794899501825 24.966385380446606 1.0825438317656295 0.9592349643091108 0.29585197824468 0.07016757961632256 754.9446966838981 906392.934699312 0.01740359106620235 0.04723404333326844 9.532462390941938e-06 5.020794899501825 -0.1233088674565187 HLRDEGLR ddPTM_PC-9_AZD4547_30min_R2 1 HLRDEGLR 8 1 Q9P0L0;Q9P0L0-2 Q9P0L0 VAPA Vesicle-associated membrane protein-associated protein A 0 78.77 0.041824 0.0 7233.2 6168.9 10675.0 12314.0 8797.2 6873.2 7171.2 8243.1 7851.7 6654.8 False True 9533.207140093644 8162.876285585524 10533.442525078912 9475.197549403494 7575.860630725413 6443.417717464077 7809.422907544802 6969.318302593875 8266.724832436757 6421.817477563474 1.484502973402893 1.2711162087843442 1.6402587837291578 1.4754697688789675 1.1797066262306475 1.003363571134818 1.2160767469379719 1.0852563665883153 1.2872874168907813 1.0 12.64876594568402 -6.305819400258455 4.770250988537141 1.1274135796587412 1.4670642172903616 0.6705999535959939 0.1168462706500451 0.125899243488536 6.722057618014934 0.03596420054388908 0.04193518050865563 4.945162869895991e-07 6.305819400258455 0.3396506376316204 HLS(ph)ESSGKPLSTK ddPTM_PC-9_AZD4547_30min_R2 1 HLSESSGKPLSTK 13 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 HLS(0.976)ES(0.012)S(0.012)GKPLSTK 66.67399999999999 0.017408 225680000.0 300590.0 276770.0 516430.0 564510.0 463980.0 373410.0 364670.0 424070.0 305390.0 359790.0 True False 396171.36733959324 366230.48996766156 509581.8007706324 434370.9410925586 399564.385877777 350060.61367023527 397124.92354060157 358539.725659156 321532.2919339584 347193.8616115535 1.1410667386246494 1.0548299680983604 1.4677154671033938 1.2510904976152497 1.1508394302339842 1.0082569203423566 1.143813204810953 1.0326787576109178 0.9260886423553603 1.0 18.405381915592315 -6.574728681613134 3.366186246274544 1.0317442301222788 1.2318065411174979 0.4391627808891344 0.11015496368135161 0.2585104487545578 6.023343055479969 0.040195541069100234 0.041288710423269426 2.6623878236766117e-07 6.574728681613134 0.2000623109952191 HLS(ph)LPAGQVVPK ddPTM_PC-9_AZD4547_30min_R2 1 HLSLPAGQVVPK 12 0 Q8IXS8 Q8IXS8 FAM126B Protein FAM126B 1 HLS(1)LPAGQVVPK 71.344 0.015655000000000002 3968400.0 48971.0 54390.0 60332.0 75104.0 56342.0 62890.0 60025.0 80163.0 53648.0 66756.0 True False 64542.759339922304 71970.50384557972 59531.9582597715 57789.933145233095 48519.885833712025 58957.47835816157 65367.108716167066 67775.65031248354 56483.72375543727 64418.89275894499 1.0019228300219445 1.11722665142496 0.924138179191307 0.8970960330144542 0.7531934150944363 0.9152203000256464 1.0147195320597995 1.0521082777082107 0.8768192270363748 1.0 15.975196243236534 -5.2778222197615285 23.542514089798896 0.9261507858213203 1.059574729127491 0.28192196832669414 0.08314232947989093 447.3031432884648 642785.5503571342 0.023714783777939587 0.04965234520379234 5.2744572932263205e-06 5.2778222197615285 0.1334239433061708 HLS(ph)PYATLTVGDSSHK ddPTM_PC-9_Lapatinib_30min_R1 1 HLSPYATLTVGDSSHK 16 0 Q9BSJ8;Q9BSJ8-2 Q9BSJ8 ESYT1 Extended synaptotagmin-1 1 HLS(1)PYATLTVGDSSHK 108.14 0.00046943 6961000.0 40232.0 29720.0 34785.0 18577.0 32155.0 33279.0 28443.0 25874.0 43340.0 20828.0 True False 39658.28430235479 29651.185165991363 31925.11157398304 19943.214551055335 30263.70611916232 31855.73474713802 29915.639367332133 27076.2004976809 38458.5928095673 24428.09204843449 1.6234703972673277 1.2138150252259101 1.3069015586925057 0.8164049206754739 1.238889474427939 1.3040615158963895 1.2246408482503373 1.1084042275588248 1.574359255455318 1.0 14.576253566128242 -1.5228791222755862 0.016852561771025783 5.49532465989979e-07 2.748879659003104 0.07680367932444832 0.21966842268989348 16098.535009655225 21.01199903495598 1333.1376701414226 2192.754553771908 0.029999973958102114 1.5228791222755862 2.748879109470638 HLS(ph)QEDNDLNK ddPTM_PC-9_Lapatinib_30min_R1 2 HLSQEDNDLNK 11 0 F5H777;A0A2R8Y4L3;A0A2R8YE98;A0A2R8Y7C3;Q8N4S0-2;Q8N4S0 F5H777 CCDC82 Coiled-coil domain-containing protein 82 1 HLS(1)QEDNDLNK;HLS(1)QEDNDLNK 112.62 0.00094333 4461100.0 33954.0 62774.0 58731.0 57752.0 63597.0 65876.0 63928.0 82253.0 60892.0 56772.0 True False 33469.80973359899 62628.65065982308 53902.36388821611 61999.274735024366 59856.34949651274 63058.63704445644 67237.8790378936 86074.7746593392 54033.70173881337 66584.96455606507 0.5026631756395566 0.9405824734965392 0.8095275599768457 0.9311302506261828 0.8989469303706428 0.9470401833939638 1.0098057344654554 1.2927058718618607 0.811500045078744 1.0 16.022908820970816 -4.163323638745992 0.552748635003426 1.0236004647637447 2.091957720052792e-18 0.49000418130614054 0.1341610983607307 6.67704447552795 0.9378431323964531 0.06976366552341053 5.092116074611696 6.865566233887228e-05 4.163323638745992 -1.0236004647637447 HLT(ph)LSQT(ph)DMAALTGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HLTLSQTDMAALTGGK 16 0 H7C183;Q70CQ2-3;Q70CQ2-2;Q70CQ2 H7C183 USP34 Ubiquitin carboxyl-terminal hydrolase 34 2 HLT(0.981)LS(0.021)QT(0.981)DMAALT(0.016)GGK 66.82600000000001 0.039334 0.0 19112.0 18505.0 15017.0 16271.0 18867.0 15943.0 16040.0 15274.0 11655.0 10108.0 True False 22347.28412079358 20342.05410471552 15375.062232289643 15359.388621293745 15170.14678789273 15106.921013952533 14520.575080456449 14873.073684140734 11825.432325906277 11940.500385116033 1.8715534022887115 1.7036182277647358 1.2876396915036183 1.286327048775895 1.2704783131871498 1.2651832441447328 1.2160776024559663 1.2455988613911178 0.9903632129727838 1.0 13.543575675783574 -1.5228787452803376 0.40660832172658173 1.1147194291735598 14.765627764092175 0.8821896236825201 0.08989939671828959 24.135749435308956 0.3167139925290721 0.0648248842701077 265.30410581945756 0.029999999999999995 1.5228787452803376 13.650908334918615 HLT(ph)PEPDIVASTK ddPTM_PC-9_AZD4547_30min_R2 4 HLTPEPDIVASTK 13 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 HLT(1)PEPDIVASTK;HLT(1)PEPDIVASTK;HLT(1)PEPDIVASTK;HLT(1)PEPDIVASTK 149.22 0.00011234 35378800.0 216307.0 215574.0 291537.0 394232.0 320172.0 296095.0 292780.0 321289.0 304925.0 293940.0 True False 285088.1265349002 285254.07972066593 287671.02889310784 303347.90322368353 275721.64437100635 277580.1328424206 318836.85280998633 271641.1675367375 321042.7129832749 283649.25006837345 1.005072731432147 1.0056577962110094 1.014178704240413 1.06944722452311 0.9720513779061423 0.978603443427085 1.1240532197181234 0.9576657349570239 1.1318299375227954 1.0 18.113748524153138 HLT(ph)PEPDIVASTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HLTPEPDIVASTK 13 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 HLT(1)PEPDIVASTK;HLT(1)PEPDIVASTK;HLT(1)PEPDIVASTK;HLT(1)PEPDIVASTK 139.66 0.00014555 28600000.0 261196.0 258159.0 274832.0 334606.0 372634.0 278536.0 342747.0 318291.0 280599.0 236330.0 True False 305411.3239438462 283787.31940660597 281385.0371861635 315859.1106272882 299619.04267555097 263929.08182539546 310279.5228866094 309936.1985071914 284702.2295338455 279174.7582127491 1.0939790040441377 1.0165221283735897 1.007917187741343 1.131402826850783 1.0732311351989137 0.9453902047414493 1.1114168231862729 1.1101870401585523 1.0197993233932852 1.0 18.09080897956769 -8.510403649054942 23.723093972363753 0.9999999843986798 1.0589376820882053 0.12963741292697017 0.054184085169789294 654.3239572426627 1244283.9899050465 0.05323384891609041 0.013744920728470394 3.087424534136304e-09 8.510403649054942 0.0589376976895255 HLT(ph)PEPDIVASTK ddPTM_PC-9_Lapatinib_30min_R1 4 HLTPEPDIVASTK 13 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 HLT(1)PEPDIVASTK;HLT(1)PEPDIVASTK;HLT(1)PEPDIVASTK;HLT(1)PEPDIVASTK 154.69 0.00024222 33599500.0 259997.0 255272.0 269762.0 249143.0 240199.0 238151.0 214377.0 223908.0 243302.0 166586.0 True False 256289.39510238988 254680.93336786484 247583.209671433 267465.8073366836 226070.9670694038 227965.83688709565 225476.3921052828 234311.58309634158 215898.76667635766 195380.16813810772 1.3117472338401688 1.3035147619887366 1.267187002809951 1.3689506457360656 1.157082467600303 1.1667808409600415 1.1540392981231395 1.1992598088599993 1.1050188395976097 1.0 17.57592450990669 -7.162214556886637 0.20298661754650543 0.9483738549894609 1.4367885864151266 0.794237603274822 0.04762437833801526 1.8979997596971878 0.25409876767594936 0.17951452836225962 0.32190872937482545 6.883121616966711e-08 7.162214556886637 0.4884147314256657 HLTDAYFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HLTDAYFK 8 0 Q02878 Q02878 RPL6 60S ribosomal protein L6 0 ; 79.906 0.016828 7734700.0 50486.0 68458.0 125513.0 142926.0 159594.0 139328.0 124407.0 108086.0 125563.0 91654.0 False True 59032.28265604769 75254.05781683946 128505.70593070345 134918.3195923442 128322.70135511502 132021.39440707388 112622.26833131851 105248.85702658337 127399.1213331418 108270.14466733525 0.5452314009316876 0.6950582549608744 1.1868988106143465 1.246126713942118 1.1852085517147144 1.2193702595735452 1.0401968952508132 0.9720949145303637 1.1766782220951228 1.0 16.724275951193086 -5.166803359226625 3.985956969745911 1.133884626138967 0.5793791691695986 0.8329081020409325 0.0917890248980042 0.08956874133247775 2.532704367584733 0.025800161459428136 0.07795051661370904 6.810776686760967e-06 5.166803359226625 -0.5545054569693684 HLTDAYFK ddPTM_PC-9_Lapatinib_30min_R1 1 HLTDAYFK 8 0 Q02878 Q02878 RPL6 60S ribosomal protein L6 0 87.696 0.009678399999999998 8241000.0 102930.0 104170.0 150210.0 108580.0 147590.0 155460.0 118070.0 99973.0 143520.0 89049.0 False True 101462.19932495001 103928.8007651856 137860.3136273678 116565.33541226173 138909.04637310424 148811.33819495988 124183.08687905304 104618.11054938004 127355.26626739955 104441.00099966588 0.9714786181077928 0.9950957935142549 1.3199826917381694 1.1160878802055396 1.330024080998119 1.4248363838971243 1.1890262032192733 1.0016957856399207 1.2193991349030346 1.0 16.67232866456839 -5.197188048937047 8.609868642050214 1.2093699183655697 0.9816311533644724 0.30531777179547603 0.13025422984249885 0.47160469365129243 59.112554604322035 0.0343375720423898 0.09139123566115585 6.350558939472202e-06 5.197188048937047 -0.22773876500109735 HLTGEFEK ddPTM_PC-9_AZD4547_30min_R2 2 HLTGEFEK 8 0 F5H018;B5MDF5;J3KQE5;P62826;H0YFC6 F5H018 RAN GTP-binding nuclear protein Ran 0 ; 117.81 0.002963 9894400.0 48176.0 47999.0 132578.0 161891.0 130245.0 128336.0 104165.0 162408.0 110743.0 122681.0 False True 63494.965876949536 63513.73807839642 130819.92909507379 124569.53114101695 112162.72994234881 120311.12963226286 113435.48320565649 137311.5753645677 116596.64889368456 118385.97553118995 0.5363385788903785 0.5364971466714239 1.1050289403630247 1.0522321633291596 0.9474325775420792 1.0162616736689871 0.9581834562470687 1.1598635290072141 0.9848856536470911 1.0 16.85313865819085 -5.256004729923477 24.98087229726732 1.0287727670638662 0.5364177922639253 0.9103797179377386 0.061692559811546484 111.22370289587286 511246.0607487218 0.01583850716377386 0.03946920500675393 5.546196725337179e-06 5.256004729923477 -0.49235497479994095 HLTGEFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HLTGEFEK 8 0 F5H018;B5MDF5;J3KQE5;P62826;H0YFC6 F5H018 RAN GTP-binding nuclear protein Ran 0 125.82 0.002912 5358200.0 19898.0 28960.0 37427.0 38598.0 46752.0 40840.0 38530.0 33528.0 34744.0 24627.0 False True 23266.338396585932 31834.957410027615 38319.4016226879 36435.47919640439 37591.28121204012 38698.27850528892 34880.15946695678 32647.925525852454 35252.06527080977 29091.68015277527 0.7997591845641953 1.0942976563349383 1.3171945182077198 1.2524364012344107 1.29216604247775 1.330218065854722 1.198973702576931 1.1222426946261448 1.211757625743277 1.0 14.828318999400507 -4.833102817562525 3.0030779147610205 1.2271890096190043 0.7552255303539369 0.6391841003677268 0.09401623747433387 0.19996440276096958 2.8126051371499403 0.023896635137384888 0.215743126993318 1.4685785561114902e-05 4.833102817562525 -0.47196347926506743 HLTGEFEK ddPTM_PC-9_Lapatinib_30min_R1 3 HLTGEFEK 8 0 F5H018;B5MDF5;J3KQE5;P62826;H0YFC6 F5H018 RAN GTP-binding nuclear protein Ran 0 ;; 138.06 0.002568 25336600.0 162332.0 174017.0 225922.0 193068.0 221923.0 239011.0 226247.0 193801.0 249755.0 177601.0 False True 160017.1159119573 173614.07432807254 207347.56524413993 207266.86477596717 208869.92545740513 228789.05669185368 237960.96262492688 202805.70196533407 221624.96186325545 208299.09621154336 0.7682084023516258 0.8334845301093118 0.9954319006433082 0.9950444747272073 1.002740430737549 1.0983679759200742 1.1424003606009872 0.973627373588648 1.0639746686091172 1.0 17.668297054122846 -5.065056514151 1.0421059785423212 1.052406206722093 0.6824781113719971 0.7955422732520275 0.048414780261058776 0.5325094437009793 0.6458138172559582 0.016831703161945082 0.19732205029375852 8.608817195266584e-06 5.065056514151 -0.36992809535009585 HLTS(ph)MATSYFGK ddPTM_PC-9_Lapatinib_30min_R1 1 HLTSMATSYFGK 12 0 K7ENL4;J3QL63;J3QL47;Q96ET8-3;J3KS67;C9JYS5;Q9NYZ1 K7ENL4 TVP23B;TVP23C Golgi apparatus membrane protein TVP23 homolog;Golgi apparatus membrane protein TVP23 homolog B 1 HLT(0.006)S(0.992)MAT(0.001)S(0.001)YFGK 76.92699999999999 0.018121 3214900.0 41883.0 32300.0 39729.0 31634.0 46637.0 40914.0 45174.0 43412.0 50063.0 46820.0 True False 41285.740739598485 32225.211334506082 36462.63497837492 33960.469887930456 43893.90335186982 39164.20359519231 47512.88868192041 45429.08000329764 44424.37775323876 54912.774616271534 0.751842190239006 0.5868436180778459 0.664010063836229 0.6184438889720103 0.799338654049059 0.7132075162632072 0.8652429059347073 0.8272952936862942 0.8089989636050026 1.0 15.744854188737369 -7.756874970278106 0.34486803970223057 1.005054764347687 0.6161765901563168 0.7215152340637963 0.062109460483657966 0.6657622372322082 0.2440818682648762 0.0873608235906358 0.08646938413322698 1.7503505272637496e-08 7.756874970278106 -0.3888781741913703 HLVYESDQNKDGK ddPTM_PC-9_AZD4547_30min_R2 2 HLVYESDQNKDGK 13 1 O43852;O43852-3;O43852-5;O43852-2;O43852-4;O43852-9;H0Y875;O43852-15 O43852 CALU Calumenin 0 ; 68.355 0.014875 14615600.0 104353.0 98388.0 152716.0 180289.0 185148.0 170221.0 132530.0 164779.0 157871.0 142084.0 False True 137535.08332276042 130189.99691779539 150690.88605713833 138726.15648728312 159443.39608711304 159577.05396095774 144324.91325537043 139316.19179472714 166215.73875996578 137109.682407004 1.003102632201376 0.9495317517499031 1.0990535709200984 1.0117896420726924 1.1628893983855377 1.1638642228581666 1.052623787917095 1.0160930238403822 1.2122830119798669 1.0 17.064970929341946 -5.394140322071698 1.7806625408465642 1.0964964414758074 0.9722874373485095 0.26185561355786313 0.07132986947393156 0.5234405349565477 3.054079421811229 0.02063239667563276 0.07133298760942111 4.0351499479132435e-06 5.394140322071698 -0.12420900412729785 HLVYESDQNKDGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HLVYESDQNKDGK 13 1 O43852;O43852-3;O43852-5;O43852-2;O43852-4;O43852-9;H0Y875;O43852-15 O43852 CALU Calumenin 0 77.744 0.0071078999999999995 2742700.0 40454.0 33672.0 30753.0 45026.0 41126.0 43561.0 42016.0 40270.0 36475.0 34177.0 False True 47302.063197079486 37014.73362950448 31486.268151401986 42503.339196261564 33067.65552546123 41276.5844752422 38035.94031050235 39212.95516959194 37008.37787107951 40373.01955501688 1.1716255984425514 0.916818559460582 0.7798839051038827 1.0527659230031499 0.8190533155539549 1.0223804146973456 0.9421128449079773 0.9712663457375513 0.916661133573318 1.0 15.301103871597936 HLVYESDQNKDGK ddPTM_PC-9_Lapatinib_30min_R1 1 HLVYESDQNKDGK 13 1 O43852;O43852-3;O43852-5;O43852-2;O43852-4;O43852-9;H0Y875;O43852-15 O43852 CALU Calumenin 0 60.255 0.026201 6965800.0 139050.0 105930.0 120300.0 113280.0 123390.0 93083.0 96190.0 96124.0 105930.0 93475.0 False True 137067.12150135305 105684.72559332004 110409.39837142931 121610.98909100195 116132.44279407382 89102.05707707108 101170.24753871535 100590.27195791452 93999.04790764811 109632.02920239154 1.2502470536991852 0.9639949781301194 1.0070907122188049 1.1092651479294984 1.059293015362161 0.8127374611718615 0.9228165188108038 0.9175263168048724 0.8574049809304961 1.0 16.742309820370885 -6.697847046152575 9.110898196079367 0.8983827465704102 1.0699648742528618 0.5250368401593897 0.08344209462977346 0.26462456278636914 35.24903109076037 0.02679487646135441 0.026751113929745798 2.0051781051923238e-07 6.697847046152575 0.17158212768245162 HLYDPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HLYDPK 6 0 A0A087X1X5;B4DDF4;B4DUT8;Q99439-2;Q99439;U3KPS3;H3BQH0;K7EQ72;E9PDU6;K7ER02;B7Z7E1;H3BVI6;P51911-2;P51911;Q15417-3;Q15417;Q15417-2 A0A087X1X5;Q15417-3 CNN2;CNN1;CNN3 Calponin;Calponin-2;Calponin-1;Calponin-3 0 77.72 0.026888 0.0 36552.0 42807.0 40067.0 45516.0 45802.0 40369.0 41532.0 41694.0 39570.0 33249.0 False True 42739.53166509243 47056.59605839269 41022.34923494365 42965.88608486302 36827.42689240805 38251.978574437024 37597.78829435891 40599.57667844462 40148.636390914755 39276.78050106083 1.088162805603124 1.1980767124515652 1.0444427652066766 1.0939258650210029 0.9376386359216327 0.9739081993597687 0.9572522954966594 1.033678834173999 1.0221977432653977 1.0 15.261389057025053 -5.828984787850017 1.6995490776953348 0.9887868858621809 1.1351503080544458 0.603278898047966 0.04612541879356334 0.23605305134209673 1.3904958025910705 0.014638274760193793 0.028936175700969714 1.4825700146163476e-06 5.828984787850017 0.14636342219226495 HLYDPK ddPTM_PC-9_Lapatinib_30min_R1 1 HLYDPK 6 0 A0A087X1X5;B4DDF4;B4DUT8;Q99439-2;Q99439;U3KPS3;H3BQH0;K7EQ72;E9PDU6;K7ER02;B7Z7E1;H3BVI6;P51911-2;P51911;Q15417-3;Q15417;Q15417-2 A0A087X1X5;Q15417-3 CNN2;CNN1;CNN3 Calponin;Calponin-2;Calponin-1;Calponin-3 0 79.454 0.044407999999999996 5111000.0 65599.0 58043.0 67302.0 55068.0 59715.0 51829.0 52542.0 58132.0 61427.0 52822.0 False True 64663.54623061678 57908.60499965131 61768.689353232934 59117.88442146286 56202.6811042071 49612.39448930006 55262.36767001956 60833.02494129963 54508.44440501363 61952.212319109196 1.043764924770431 0.934730219178781 0.9970376688901608 0.9542497710485783 0.9071940936461336 0.8008171561937439 0.8920160491665582 0.9819346664805971 0.8798466166832991 1.0 15.918868181605706 -6.096891564582977 3.191705852161395 0.9031549794980029 0.9855015639110211 0.28440487205322684 0.05735601983160915 0.3381513335726756 6.570531397687898 0.01788543745399604 0.024601348168042714 8.000339839766602e-07 6.096891564582977 0.08234658441301812 HLYISS(ph)SNPDLITR ddPTM_PC-9_Lapatinib_30min_R1 1 HLYISSSNPDLITR 14 0 Q16825 Q16825 PTPN21 Tyrosine-protein phosphatase non-receptor type 21 1 HLYISS(0.599)S(0.4)NPDLIT(0.001)R 90.75399999999999 0.0080092 0.0 14858.0 16826.0 21623.0 16244.0 20190.0 19379.0 20706.0 18361.0 17382.0 13542.0 True False 14646.122195376509 16787.04043078636 19845.240407193778 17438.637948395473 19002.463895067263 18550.20534465542 21778.05536476389 19214.11909012596 15424.25611942545 15882.716656419236 0.9221421317402311 1.056937600407398 1.24948652277147 1.097963171265628 1.1964240316147134 1.1679491453471267 1.3711794925184897 1.2097501646458126 0.9711346272233289 1.0 13.955170078650985 -4.950434153862004 3.3414047503459394 1.1725625913178064 0.923799794025172 0.29536668959151513 0.11137464684848668 0.29673320671346776 6.328006019084891 0.028440294397407757 0.15311141810360968 1.120897359604428e-05 4.950434153862004 -0.2487627972926344 HMDPPPAPVQDRS(ph)PSPR ddPTM_PC-9_AZD4547_30min_R2 5 HMDPPPAPVQDRSPSPR 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 HMDPPPAPVQDRS(0.834)PS(0.166)PR;HMDPPPAPVQDRS(0.752)PS(0.248)PR;HMDPPPAPVQDRS(0.815)PS(0.185)PR;HMDPPPAPVQDRS(0.769)PS(0.231)PR;HMDPPPAPVQDRS(0.726)PS(0.274)PR 84.62 0.0015959000000000001 32712000.0 69838.2 61399.200000000004 101195.1 134701.1 122931.4 102454.8 91632.2 127261.7 83463.8 109781.2 True False 92045.29487519893 81245.29067320321 99853.18685429622 103647.84250624938 105864.49706042354 96048.2851596402 99787.28828490729 107596.32844793987 87875.52607327526 105937.79360279672 0.8688617323890439 0.7669150726116157 0.9425643432662555 0.978384002359599 0.9993081171517693 0.9066479666337374 0.9419422935977868 1.015655742759394 0.8295011920179861 1.0 16.692857841068914 -5.32301849571096 7.545090896118992 0.95333095770399 0.8182173788738907 0.4746020713106299 0.05633750381546977 0.20180710461459503 22.148982737299185 0.01399453264760685 0.029439742680107392 4.753149828218182e-06 5.32301849571096 -0.13511357883009933 HMDPPPAPVQDRS(ph)PSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 HMDPPPAPVQDRSPSPR 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 HMDPPPAPVQDRS(0.873)PS(0.127)PR;HMDPPPAPVQDRS(0.708)PS(0.292)PR;HMDPPPAPVQDRS(0.814)PS(0.186)PR;HMDPPPAPVQDRS(0.616)PS(0.384)PR;HMDPPPAPVQDRS(0.712)PS(0.288)PR 100.39 0.0017733 39841900.0 124944.4 108052.2 144219.0 164639.0 180721.0 168745.0 173777.0 194493.0 153311.9 124721.7 True False 146095.01915561358 118778.9083238878 147657.7279136032 155414.81059684 145310.01736655357 159895.71514140483 157315.5845234716 189387.76483236798 155553.79649988058 147332.75691356594 0.9915990321237355 0.806194839573731 1.0022056941500652 1.0548557826011187 0.9862709448368021 1.0852692808511624 1.067757013572767 1.2854423469688683 1.0557991295251306 1.0 17.168718698991412 -6.053750607151425 0.7938810423367989 1.1207528718661772 0.8946212627658567 0.370517745716221 0.08907203449048812 0.7099177759241312 0.9093758606757826 0.04540579317910804 0.1026746391857788 8.835871531413377e-07 6.053750607151425 -0.22613160910032049 HMDPPPAPVQDRS(ph)PSPR ddPTM_PC-9_Lapatinib_30min_R1 4 HMDPPPAPVQDRSPSPR 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 HMDPPPAPVQDRS(0.908)PS(0.092)PR;HMDPPPAPVQDRS(0.957)PS(0.043)PR;HMDPPPAPVQDRS(0.757)PS(0.243)PR;HMDPPPAPVQDRS(0.917)PS(0.083)PR 88.76799999999999 0.0012626 21241500.0 75449.6 79305.4 77821.5 81481.3 86520.2 80843.1 72763.1 75634.0 75843.9 54270.2 True False 74373.67486823803 79121.77321880909 71423.3166696773 87473.70661564857 81431.25194125801 77385.62906747055 76530.41728541744 79148.23175549206 67301.56131032627 63650.73175950403 1.168465354793551 1.243061486201924 1.1221130487476714 1.3742765275057094 1.2793451024088043 1.2157853794966889 1.2023493708537023 1.2434771693520086 1.0573572282659125 1.0 15.957889479689266 -8.357499193616636 3.431442216949214 1.0025867090827016 1.2333842985642476 0.6224325726972927 0.0636188715634455 0.15458931481573301 3.2324722549952414 0.0614139784088137 0.01653071434268728 4.390366808287068e-09 8.357499193616636 0.23079758948154594 HMQLYCDR ddPTM_PC-9_AZD4547_30min_R2 1 HMQLYCDR 8 0 P33992;B1AHB1;B1AHB2 P33992 MCM5 DNA replication licensing factor MCM5;DNA helicase 0 63.534 0.039112 1194600.0 8065.4 6130.7 6433.8 7470.7 5971.9 6296.1 4115.5 6342.8 7270.7 9191.4 False True 10630.029429258326 8112.328882627236 6348.483608229756 5748.445536164419 5142.804767497507 5902.403871693766 4481.771527220079 5362.666003044056 7655.014358571761 8869.611883644422 1.1984774045029092 0.9146205030218271 0.7157566409344663 0.648105645610555 0.5798229770324953 0.6654636019167657 0.5052951116704975 0.6046111231690781 0.863060803448189 1.0 13.114655261139713 -4.875659794298749 1.6515245244422863 0.664398285343377 1.329742978530612 0.5586194173270769 0.13750648400272872 0.5369316377052525 1.6716346400645756 0.03714257262683966 0.544508446468595 1.3314970411914735e-05 4.875659794298749 0.6653446931872351 HMQLYCDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HMQLYCDR 8 0 P33992;B1AHB1;B1AHB2 P33992 MCM5 DNA replication licensing factor MCM5;DNA helicase 0 75.043 0.018272 1232600.0 5906.0 4608.2 7998.1 6894.0 10406.0 9928.8 6404.7 7922.5 9658.7 9960.0 False True 6905.7691511828625 5065.671641467171 8188.80503696316 6507.7515306495625 8367.019000096032 9408.116249346536 5798.00044998749 7714.54276958262 9799.940215034832 11765.669156683382 0.5869423200005673 0.43054683707383207 0.6959914415332327 0.5531135920945808 0.7111383881930101 0.799624409292721 0.492789689457993 0.6556824492383796 0.8329267196390666 1.0 13.522295753794241 -14.522878745014665 0.10474581109456013 2.2189442089322133 0.39937491469179975 0.5854270454656836 0.10457297214116637 130.84109737512009 0.9190950136416017 34.134652524185064 1.565207362320192 3.000000001835198e-15 14.522878745014665 -1.8195692942404136 HMS(ph)VSSIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HMSVSSIK 8 0 Q5TEJ0;P15927;P15927-2;P15927-3 Q5TEJ0 RPA2 Replication protein A 32 kDa subunit 1 HMS(0.998)VS(0.002)SIK 90.709 0.0081648 8404900.0 37699.0 53314.0 40250.0 42447.0 33511.0 31860.0 37968.0 22792.0 25424.0 22686.0 True False 44080.69611080978 58606.661580048756 41209.71264897505 40068.83220503077 26944.760110726307 30189.205513675457 34371.39617548442 22193.734150120166 25795.777902517486 26798.792217722817 1.6448762225059508 2.1869142871778555 1.5377451459070561 1.4951730615132757 1.0054468086403894 1.1265136603324406 1.2825725837283675 0.8281617309396058 0.9625724059854456 1.0 14.709880361547189 -5.882983831126945 1.405633334643592 1.0289650020777428 1.9153282587874298 0.7813630169128813 0.18369263129665891 0.1843661465770679 0.7391462630919942 0.06217406592173689 0.1272256832895755 1.3092306650195104e-06 5.882983831126945 0.8863632567096871 HMSVS(ph)SIK ddPTM_PC-9_AZD4547_30min_R2 1 HMSVSSIK 8 0 Q5TEJ0;P15927;P15927-2;P15927-3 Q5TEJ0 RPA2 Replication protein A 32 kDa subunit 1 HMS(0.111)VS(0.874)S(0.016)IK 87.30799999999999 0.010412000000000001 18876000.0 41286.0 45703.0 34835.0 44407.0 42472.0 40928.0 49167.0 50079.0 47401.0 32007.0 True False 54414.08919785244 60475.60097912357 34373.06513921532 34169.65223131079 36575.49592008478 38368.765689979904 53542.767750900224 42340.44125093698 49906.52008894053 30886.44467217257 1.7617466100550356 1.957998132223021 1.112885134694187 1.1062993035937303 1.1841924931242673 1.2422525835273168 1.7335361294963185 1.370842183369975 1.615806565587145 1.0 14.914686191951473 -5.254949410789415 24.939292218796073 1.3119487792607833 1.859872420197467 0.5069530500485404 0.22208120460133593 429.91452443371156 1652040.2742423562 0.060014914486166644 0.15097772521351263 5.559690160843536e-06 5.254949410789415 0.5479236409366837 HMVMHS(ph)GDGTYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HMVMHSGDGTYK 12 0 K7EQV7;A0A087WVH9;Q9H0M5 K7EQV7 ZNF700 Zinc finger protein 700 1 HMVMHS(0.998)GDGT(0.002)YK 64.654 0.038296 12538000.0 9757.2 15024.0 11015.0 12440.0 12511.0 9055.2 11721.0 11771.0 10380.0 8464.1 True False 11408.901246515643 16515.483429843054 11277.639374620132 11743.027131024162 10059.559360964962 8580.32937123145 10610.7020273086 11462.023722405424 10531.787862969299 9998.574328221268 1.141052801329254 1.6517838331438532 1.127924742509406 1.174470153997768 1.0060993728447427 0.8581552818998625 1.0612214980849404 1.1463658063783682 1.0533289564336208 1.0 13.287506683925868 -5.452611769095012 6.894588098315639 1.0483497841331042 1.3984945321872277 0.4968763648275262 0.14021371293366233 0.19449786026539745 16.12002647503506 0.03618338115126928 0.07552549887925077 3.526860084245647e-06 5.452611769095012 0.35014474805412354 HMVT(ph)HT(ph)S(ph)NGPY(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 HMVTHTSNGPYK 12 0 Q9BS34 Q9BS34 ZNF670 Zinc finger protein 670 4 HMVT(1)HT(1)S(1)NGPY(1)K 46.88 0.042543 0.0 10421.0 11084.0 14218.0 9467.5 10376.0 13813.0 13347.0 14078.0 10874.0 10171.0 True False 10272.394629022649 11058.335678998925 13049.050923067152 10163.771532654158 9765.704080000882 13222.250189675686 14038.042352627435 14732.115274265747 9649.25561170362 11929.043797994393 0.8611247307809975 0.9270093954100614 1.0938890948879796 0.852018963528575 0.8186493607847068 1.1084082189302311 1.176795272978009 1.2349787228329758 0.8088876003058963 1.0 13.542190784428438 -6.778985792543777 24.992583076839658 1.087436511050121 0.9183884437891746 0.2601060114245901 0.12803706637309537 323.1838620564498 460330.3932925728 0.045601624089823975 0.040305504385541396 1.663467067936962e-07 6.778985792543777 -0.16904806726094634 HNGPNDASDGTVR ddPTM_PC-9_AZD4547_30min_R2 2 HNGPNDASDGTVR 13 0 P31942;P31942-2 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 0 ; 159.12 0.00021901 11745000.0 13211.7 10959.1 24518.2 38197.0 28918.0 27749.0 19242.0 29497.0 21602.4 23627.6 False True 17412.74577956856 14501.414758119012 24193.072648092704 29391.271787767208 24903.234861014582 26013.850643355458 20954.500723306734 24938.916423628434 22744.258761826313 22800.40491568173 0.7637033571975017 0.6360156677807588 1.0610808333256012 1.2890679747337466 1.092227745652296 1.1409380991064582 0.9190407276010517 1.0937926986759727 0.9975374931250979 1.0 14.476771825196431 -5.270136564070518 22.67950645615934 1.0827187740234252 0.6998595026137927 0.7003407165046551 0.09782206457771238 84.03499217169852 219139.215312073 0.02631642454281058 0.05640457279750408 5.368629530586373e-06 5.270136564070518 -0.3828592714096325 HNGPNDASDGTVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HNGPNDASDGTVR 13 0 P31942;P31942-2 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 0 ;; 152.0 0.00011499999999999999 5745130.0 14053.8 14822.0 21812.4 18756.5 21190.8 24565.0 21088.1 18845.2 21345.2 17581.3 False True 16432.830764797432 16293.43020481456 22332.49033998765 17705.634114393466 17038.61485943062 23276.768155789 19090.4825033774 18350.533468139893 21657.33316884897 20768.650516505764 0.791232475684327 0.7845204093479955 1.0752980951862536 0.852517312105667 0.8204006729223587 1.120764593601781 0.9191970604062767 0.8835688892523813 1.0427896194621278 1.0 14.34211985685887 -5.230606498187194 24.416753448474328 0.9550020440854106 0.7878763174436875 0.361615295695747 0.09311697509786832 577.6369396690966 457431.6899751556 0.023501816132182097 0.06216253745515338 5.880219010618115e-06 5.230606498187194 -0.1671257266417231 HNGPNDASDGTVR ddPTM_PC-9_Lapatinib_30min_R1 2 HNGPNDASDGTVR 13 0 P31942;P31942-2 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 0 ; 141.73 4.8827e-05 14095500.0 21121.4 17573.4 20994.0 18364.5 21071.0 20827.9 20672.0 18202.7 21367.0 16540.5 False True 20820.204962809614 17532.70987200647 19267.954359183557 19715.08659217611 19831.645207179885 19937.139269206276 21742.295011127164 19048.4638942234 18960.4234555151 19399.503386169126 1.0732339147224448 0.9037710668669187 0.9932189487345662 1.0162675919957818 1.0222759218320432 1.0277138992857136 1.1207655463298267 0.98190471761272 0.9773664344950672 1.0 14.243732100442191 -5.749489632206963 3.729985491212432 1.0252026678445076 0.980085522034963 0.057297506868583814 0.05341387180255652 0.498022697406312 14.893730825932561 0.01518231712316035 0.02594495067792449 1.780370410640858e-06 5.749489632206963 -0.04511714580954462 HNGS(ph)SEILNK ddPTM_PC-9_AZD4547_30min_R2 4 HNGSSEILNK 10 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2 Q8TDM6-4 DLG5 Disks large homolog 5 1 HNGS(0.76)S(0.24)EILNK;HNGS(0.972)S(0.028)EILNK;HNGS(0.821)S(0.179)EILNK;HNGS(0.829)S(0.171)EILNK 110.31 0.00099664 23856800.0 228309.0 206839.0 330465.0 424352.0 390937.0 339044.0 295638.0 357031.0 278339.0 322632.0 True False 300906.5128777914 273695.6617929009 326082.81817800505 326524.20257304446 336662.14561382117 317843.5250829151 321949.20927330636 301860.06270619057 293051.43129966926 311336.7518815385 0.9664985295159895 0.8790984685837546 1.0473637185695228 1.048781425898876 1.0813440545622408 1.0208994703068413 1.034086747959026 0.9695612897671851 0.9412683518043939 1.0 18.248116364856585 -5.267626201934259 24.89889011840414 1.0208781500300934 0.9227984974844237 0.43727446101269607 0.04305473030467959 403.7202436542386 1624779.9688456967 0.012076828654639616 0.026219866674270887 5.399751802023132e-06 5.267626201934259 -0.09807965254566975 HNGS(ph)SEILNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HNGSSEILNK 10 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2 Q8TDM6-4 DLG5 Disks large homolog 5 1 HNGS(0.787)S(0.213)EILNK;HNGS(0.977)S(0.023)EILNK;HNGS(0.5)S(0.5)EILNK;HNGS(0.864)S(0.136)EILNK 107.39 0.0012352 22025300.0 196410.0 211991.0 247959.0 300558.0 317818.0 301492.0 280763.0 305158.0 266518.0 231246.0 True False 229658.3337256737 233036.06548028943 253871.28294974397 283718.7096821828 255543.84437560244 285681.2287736669 254167.0960919069 297147.9258416269 270415.3215474803 273169.06925767154 0.840718659509157 0.8530836456468431 0.9293558880572801 1.0386194544396246 0.9354786948245455 1.0458037198354733 0.9304387820429234 1.0877802770610785 0.9899192550691246 1.0 18.059434611963702 -5.452399056086906 2.7164870289335177 1.0035425553378066 0.844437233948917 0.6543988432381089 0.045604180280667546 0.15659812019405334 2.2399334617558617 0.012010463812025016 0.028950836329462215 3.5285879274518577e-06 5.452399056086906 -0.15910532138888955 HNGS(ph)SEILNK ddPTM_PC-9_Lapatinib_30min_R1 4 HNGSSEILNK 10 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2 Q8TDM6-4 DLG5 Disks large homolog 5 1 HNGS(0.903)S(0.097)EILNK;HNGS(0.969)S(0.031)EILNK;HNGS(0.5)S(0.5)EILNK;HNGS(0.823)S(0.177)EILNK 97.463 0.0029104 22540100.0 251833.0 212234.0 227815.0 204522.0 234066.0 226334.0 189517.0 192868.0 256018.0 180260.0 True False 248241.81523948372 211742.58521261797 209084.9300913304 219563.23014539137 220298.69807146167 216654.2224303237 199329.2629461974 201829.3513792504 227182.55685094165 211417.70081864853 1.1741770640691171 1.0015366943860964 0.9889660576276953 1.038528133146855 1.0420068765218062 1.0247686054261227 0.9428220161999565 0.9546473667896763 1.0745673421442419 1.0 17.689736644980606 -4.760492515004898 24.92442477942126 1.0061021251734803 1.1741772693012729 0.6345872321692904 0.037921247976899795 15.133194082180689 398134.9416342587 0.00983897209671999 0.058185783430901125 1.7358311793830682e-05 4.760492515004898 0.16807514412779256 HNGSLS(ph)PGLEAR ddPTM_PC-9_AZD4547_30min_R2 6 HNGSLSPGLEAR 12 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 HNGSLS(1)PGLEAR;HNGS(0.359)LS(0.641)PGLEAR;HNGSLS(1)PGLEAR;HNGS(0.005)LS(0.995)PGLEAR;HNGS(0.055)LS(0.945)PGLEAR;HNGS(0.01)LS(0.99)PGLEAR 122.16 0.00023445 329975900.0 126368.0 111212.7 180127.0 223119.0 188170.0 196034.0 170634.0 248017.0 194061.0 191519.0 True False 166550.3953823142 147160.03039211803 177738.39828710884 171682.36170418686 162045.84355062988 183775.9629903616 185820.09543814175 209691.6715136807 204318.66827661617 184813.97810384686 0.9011785639327001 0.7962602823766333 0.9617151262619201 0.9289468440948695 0.8768051270428063 0.9943834599301682 1.005443946094432 1.1346093713531509 1.1055368775288719 1.0 17.49571435120412 -7.134312954739374 1.4959065433321794 1.0864885790036765 0.8907560509865694 0.6789493007909844 0.054811196274039194 0.22740169622761142 1.0092073285533603 0.02992469135595329 0.01982413333786447 7.339847645118679e-08 7.134312954739374 -0.19573252801710705 HNGSLS(ph)PGLEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 HNGSLSPGLEAR 12 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 HNGSLS(1)PGLEAR;HNGS(0.005)LS(0.995)PGLEAR;HNGS(0.002)LS(0.998)PGLEAR;HNGS(0.061)LS(0.939)PGLEAR;HNGS(0.046)LS(0.954)PGLEAR 125.39 0.00016688 239329400.0 125429.0 140733.0 166443.0 173251.0 208135.0 194712.0 197192.0 150357.0 159329.0 148620.0 True False 146661.65236432673 154704.04216800453 170411.63235859244 163544.30815732072 167352.44085959904 184500.95994911424 178512.5462135511 146410.28806641028 161658.88520414618 175563.6295247273 0.8353760557431978 0.8811850301045138 0.9706545303256605 0.9315386598013246 0.953229557355604 1.0509065029504199 1.016796854204979 0.8339442996408838 0.9207994027110115 1.0 17.42163447569368 -5.074051516533832 2.8679173565846257 0.9580576773566437 0.8373367174292087 0.3529402965429148 0.056309777856231466 0.34633499585715316 5.244063456856996 0.016204342518980615 0.06969127442358573 8.432347263139526e-06 5.074051516533832 -0.12072095992743503 HNGSLS(ph)PGLEAR ddPTM_PC-9_Lapatinib_30min_R1 6 HNGSLSPGLEAR 12 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 HNGS(0.001)LS(0.999)PGLEAR;HNGS(0.004)LS(0.996)PGLEAR;HNGSLS(1)PGLEAR;HNGS(0.004)LS(0.996)PGLEAR;HNGSLS(1)PGLEAR;HNGS(0.001)LS(0.999)PGLEAR 135.57 3.445e-05 257949900.0 139112.0 128586.0 158590.0 122343.0 192076.0 188224.0 176661.0 178607.0 216451.0 150668.0 True False 137128.23736998334 128288.26701730049 145551.34237510356 131340.51234428422 180778.4673159454 180174.09829157445 185807.64217108823 186905.73325691035 192072.00904992266 176710.76304750942 0.776003877778038 0.7259787961122077 0.8236699330870496 0.743251345188141 1.0230189955511786 1.019598892474557 1.0514789193747813 1.0576929782520377 1.086928751466504 1.0 17.43103038825037 -6.286883032353044 6.428808901246394 1.0432089169739984 0.7680086085548047 0.944339035105372 0.03241593700851431 0.038121959490823226 6.045802202402725 0.009977722750721464 0.011628287997609428 5.165554733709138e-07 6.286883032353044 -0.27520030841919374 HNGVGGS(ph)PPK ddPTM_PC-9_AZD4547_30min_R2 4 HNGVGGSPPK 10 0 Q96ST3 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 HNGVGGS(1)PPK;HNGVGGS(1)PPK;HNGVGGS(1)PPK;HNGVGGS(1)PPK 132.56 0.00014227 72235900.0 765274.0 739714.0 634300.0 721500.0 713393.0 778790.0 736370.0 732099.0 723810.0 725029.0 True False 1008615.213311955 978812.0846043226 625888.7675557432 555169.3220638807 614350.6960095358 730092.138186557 801905.5034622912 618969.9215114068 762069.1189125977 699645.955391652 1.4416080097931052 1.399010566789309 0.8945792693182647 0.7935003665576895 0.8780879690294657 1.0435165565673308 1.146158992677083 0.8846902018677663 1.0892210739444668 1.0 19.41626552847366 -5.254201073884043 23.51713326868628 0.9619720443775691 1.4203094773176193 0.7584006651507516 0.1024956458453546 120.77094445572317 392376.26731287845 0.028457269078537368 0.07178710115794096 5.569278373634038e-06 5.254201073884043 0.45833743294005014 HNGVGGS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 HNGVGGSPPK 10 0 Q96ST3 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 HNGVGGS(1)PPK;HNGVGGS(1)PPK;HNGVGGS(1)PPK;HNGVGGS(1)PPK;HNGVGGS(1)PPK 81.789 0.008956 86983300.0 1008113.0 1019698.0 746807.0 1032258.0 1030793.0 874308.0 1059452.0 834546.0 764994.0 805438.0 True False 1178766.619760654 1120926.8784906908 764613.7111613207 974423.930885591 828816.5112594658 828457.74934873 959093.0367917551 812640.0517745776 776180.590023539 951457.5335562982 1.2389061815031661 1.1781155111578767 0.8036235819200417 1.0241381212711096 0.8711019483566098 0.8707248827513853 1.008025059412707 0.8541001811579993 0.8157805920379652 1.0 19.859779740505253 -5.16848336765803 5.607663743053007 0.9064892142668274 1.220675344274569 0.717040941636517 0.07621915211896194 0.1095886429434247 5.207991995531378 0.018786552455486567 0.05198079130481956 6.784481027873518e-06 5.16848336765803 0.31418613000774165 HNGVGGS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 4 HNGVGGSPPK 10 0 Q96ST3 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 HNGVGGS(1)PPK;HNGVGGS(1)PPK;HNGVGGS(1)PPK;HNGVGGS(1)PPK 103.14 0.0029471999999999996 82897500.0 1000500.0 966290.0 756508.0 843533.0 880938.0 905980.0 830053.0 795558.0 775910.0 688706.0 True False 986232.6865307719 964052.6148736784 694310.8324453279 905569.2307635989 829122.9588307454 867233.347342532 873029.0828594785 832522.5290072652 688518.8451054763 807747.9144569371 1.2209659336524974 1.1935067830188428 0.8595637574776347 1.1211037683364726 1.0264625188022665 1.073643561092433 1.0808187396515052 1.0306712206951156 0.8523932191993085 1.0 19.623545595004494 -5.106640981807646 8.808767044972598 1.01677175874762 1.2141006235205285 0.47700346688228956 0.0840150132373709 0.25821674840198316 19.091666277514427 0.021026399422543977 0.056077817308667295 7.82274219946212e-06 5.106640981807646 0.19732886477290856 HNKPEVEVR ddPTM_PC-9_AZD4547_30min_R2 2 HNKPEVEVR 9 1 H7C0A3;F8WCF6;P59998;P59998-3;F8WE39;F8WDD7;A0A0A6YYG9;P59998-2 H7C0A3 ARPC4-TTLL3;ARPC4 Actin-related protein 2/3 complex subunit 4 0 ; 54.608000000000004 0.042529000000000004 8549400.0 36503.0 38221.4 45338.0 56840.0 53321.0 53515.0 39075.7 53477.4 44240.0 47221.0 False True 48110.19469043277 50575.72008978567 44736.78849667704 43736.416169245924 45918.299537456194 50168.69859018944 42553.36160033864 45213.6966184001 46578.436082249966 45567.80716295377 1.055793501723426 1.1099002396346007 0.9817630314466319 0.959809543014465 1.0076916664707836 1.1009680235606367 0.9338470347753348 0.9922289316383527 1.022178572598021 1.0 15.475727325681133 -5.265285810196834 24.998204123537842 0.9996430562886771 1.0828468730096645 0.3723730650788015 0.04312049102106689 321.4747774051124 2089303.339559114 0.011488248719037681 0.02531544660157386 5.428929348152195e-06 5.265285810196834 0.08320381672098742 HNKPEVEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HNKPEVEVR 9 1 H7C0A3;F8WCF6;P59998;P59998-3;F8WE39;F8WDD7;A0A0A6YYG9;P59998-2 H7C0A3 ARPC4-TTLL3;ARPC4 Actin-related protein 2/3 complex subunit 4 0 ;; 61.78 0.029025 8275100.0 22606.4 23033.2 27497.0 30373.0 33380.0 27809.7 31526.6 30682.6 30006.199999999997 24676.6 False True 26433.21702324759 25319.78387488426 28152.632762953195 28671.299280594594 26839.428620334944 26351.310375821093 28540.172215181934 29877.21426090193 30444.983908846752 29150.27224014189 0.9067914290984654 0.8685951083508994 0.9657759807877582 0.9835688340883583 0.9207265166935642 0.9039816218091288 0.9790705205106178 1.0249377437977745 1.044415079833181 1.0 14.831221736651674 -7.532507946245854 3.2374275028239845 1.0255734570986168 0.9268854340128863 0.6567677487230066 0.03196100926818131 0.16825991546116092 3.671454774950371 0.017844372609878135 0.010110773915816124 2.9342158163901722e-08 7.532507946245854 -0.09868802308573055 HNKPEVEVR ddPTM_PC-9_Lapatinib_30min_R1 2 HNKPEVEVR 9 1 H7C0A3;F8WCF6;P59998;P59998-3;F8WE39;F8WDD7;A0A0A6YYG9;P59998-2 H7C0A3 ARPC4-TTLL3;ARPC4 Actin-related protein 2/3 complex subunit 4 0 ; 55.06399999999999 0.04167 9986200.0 37317.0 37455.0 36581.0 32915.0 31163.0 38461.0 33667.0 33922.0 33137.0 32520.0 False True 36784.85273690031 37368.27524872832 33573.45138674354 35335.67890122118 29330.053608815302 36816.11268696999 35410.112526103854 35498.13995834939 29404.762111920438 38141.03866982379 0.9644428683585783 0.9797393189056789 0.8802448113010092 0.926447735393684 0.768989378152947 0.9652624566854795 0.9283992717827956 0.9307072171171522 0.7709481214308075 1.0 15.219056511700384 -5.258657677770682 24.582763184190313 0.8940286791119133 0.9720911017477998 0.15188857209287931 0.07139499793751725 334.34876004073874 2954690.2307753973 0.017757844572202326 0.0428196702424817 5.51242028540453e-06 5.258657677770682 0.07806242263588647 HNLFEDNMALPS(ph)ESVSSLTDLKPPTGSNQASPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HNLFEDNMALPSESVSSLTDLKPPTGSNQASPAR 34 1 Q9BZQ8 Q9BZQ8 FAM129A Protein Niban 1 HNLFEDNMALPS(0.277)ES(0.277)VS(0.209)S(0.209)LT(0.028)DLKPPTGSNQASPAR;HNLFEDNMALPS(0.231)ES(0.231)VS(0.231)S(0.231)LT(0.075)DLKPPTGSNQASPAR 63.881 2.5943000000000002e-05 20649000.0 24862.5 32517.0 36787.0 45520.0 55102.0 44119.0 49940.0 47235.0 42099.0 32927.1 True False 29071.230193241434 35745.07286263359 37664.141595474386 42969.66197783115 44305.15865301665 41805.321972939346 45209.32166571038 45995.1312996194 42714.618231516826 38896.52257921981 0.7473992086061835 0.918978625655604 0.968316422599592 1.1047173147757785 1.1390519181446408 1.0747830191708074 1.1622972612431717 1.1824998290256408 1.0981603341152355 1.0 15.247353560931453 -4.920995131004994 0.9230263667541698 1.1248019874857376 0.606369451470378 0.8259006858644257 0.05291924784932033 0.6480195762960445 0.5041849624779567 0.018054245108577963 0.3235471527361406 1.1995127511416955e-05 4.920995131004994 -0.5184325360153595 HNLFEDNMALPSES(ph)VSSLTDLKPPTGSNQASPAR ddPTM_PC-9_AZD4547_30min_R2 1 HNLFEDNMALPSESVSSLTDLKPPTGSNQASPAR 34 1 Q9BZQ8 Q9BZQ8 FAM129A Protein Niban 1 HNLFEDNMALPS(0.083)ES(0.278)VS(0.278)S(0.278)LT(0.083)DLKPPTGSNQASPAR 94.20700000000001 6.5153e-16 13966000.0 18969.0 19719.0 23908.0 29034.0 25715.0 31782.0 22070.0 36166.0 22931.0 24833.0 True False 25000.74742028927 26092.781123937966 23590.964298790295 22340.659870828404 22144.91612321011 29794.666515806814 24034.187244744786 30577.375712002795 24143.085845435653 23963.604228576918 1.0432799332612723 1.0888504448267418 0.9844497544596299 0.9322746135235729 0.9241062367739324 1.24332993616529 1.002945425717042 1.275992351582024 1.0074897588504113 1.0 14.548557291500783 -6.744441722058731 24.999990908315635 1.1167631820752715 0.9958032226146908 0.23297724058851543 0.10005948454628576 335.60604517832456 493605.2673222128 0.03193112664677986 0.031852190356836 1.8011848190703821e-07 6.744441722058731 -0.12095995946058069 HNLFEDNMALPSESVS(ph)SLTDLKPPTGSNQASPAR ddPTM_PC-9_Lapatinib_30min_R1 1 HNLFEDNMALPSESVSSLTDLKPPTGSNQASPAR 34 1 Q9BZQ8 Q9BZQ8 FAM129A Protein Niban 1 HNLFEDNMALPS(0.065)ES(0.065)VS(0.29)S(0.29)LT(0.29)DLKPPTGSNQASPAR 57.427 0.00034829 4789900.0 7798.1 6672.0 7276.6 6936.8 6343.0 7061.2 6338.5 4641.7 6163.5 4614.2 True False 7686.897664003598 6656.551393926455 6678.346036488285 7446.955412486438 5969.917210817807 6759.208936461157 6666.6765154813065 4857.370327358952 5469.3017254676515 5411.7583219649705 1.4204066786952416 1.230016382459132 1.2340436581180192 1.3760694712217862 1.1031381772144941 1.2489857333479253 1.231887331040438 0.8975586192835151 1.0106330327555697 1.0 12.40188169761144 -7.714322501604899 7.114556530533198 0.9658988699585219 1.2597882955551187 0.7106217286607204 0.08601220520197296 0.10667651084266896 12.801537360584463 0.040747619740794695 0.023050283965384215 1.93053419425751e-08 7.714322501604899 0.2938894255965968 HNPT(ph)GAVLFMGQINKP ddPTM_PC-9_AZD4547_30min_R2 1 HNPTGAVLFMGQINKP 16 1 P07093-2;P07093;P07093-3 P07093-2 SERPINE2 Glia-derived nexin 1 HNPT(1)GAVLFMGQINKP 73.38600000000001 0.026967 13009000.0 16532.0 13380.0 20188.0 38562.0 29902.0 24899.0 19887.0 24629.0 15966.0 26581.0 True False 21788.832113038243 17704.82333983924 19920.29392939512 29672.126676960976 25750.623446090944 23342.061593891955 21656.904473776147 20823.15396811692 16809.930164764977 25650.40728062673 0.8494536509560586 0.6902355641429273 0.7766073150986785 1.156789689626947 1.003907000944188 0.91000744504832 0.8443103548742947 0.8118059779832134 0.6553474952992736 1.0 14.646694112870104 -10.592961754031101 16.155272467481687 0.9999997332589046 0.8614428479900865 0.08794702366600515 0.1384809336852197 0.0 0.0 0.14696502198929356 0.035644253466651746 2.5529261151737712e-11 10.592961754031101 -0.13855688526881804 HNPT(ph)GAVLFMGQINKP ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HNPTGAVLFMGQINKP 16 1 P07093-2;P07093;P07093-3 P07093-2 SERPINE2 Glia-derived nexin 1 HNPT(1)GAVLFMGQINKP 78.814 0.017427 8723200.0 24113.0 18224.0 24693.0 33060.0 37814.0 32129.0 30437.0 41104.0 29336.0 22682.0 True False 28194.8546465412 20033.158281779804 25281.774768723975 31207.75538196613 30404.61815007027 30444.09868012802 27553.787015202783 40025.06355328797 29764.983501740604 26794.067049386795 1.0522797675534838 0.7476714246051079 0.9435586886501641 1.1647263300656832 1.13475188720057 1.1362253675044363 1.0283540368998731 1.4938032169402955 1.1108796379018466 1.0 14.709625962844203 -5.7109973298093415 4.2710253704287044 1.1677051672611243 0.888710447413346 0.3639327302977903 0.14364624669444778 0.20066555421106289 7.587446054183605 0.039407928731086915 0.06864713450153702 1.945372042396982e-06 5.7109973298093415 -0.27899471984777824 HNPT(ph)GAVLFMGQINKP ddPTM_PC-9_Lapatinib_30min_R1 1 HNPTGAVLFMGQINKP 16 1 P07093-2;P07093;P07093-3 P07093-2 SERPINE2 Glia-derived nexin 1 HNPT(1)GAVLFMGQINKP 90.759 0.006333 10570000.0 14471.0 33010.0 53084.0 49601.0 43307.0 39212.0 32703.0 30044.0 44777.0 32310.0 True False 14264.640886343615 32933.56737312834 48719.638430165774 53248.82300408546 40759.76740483793 37534.99416763651 34396.20132299208 31439.953921014338 39733.742737286484 37894.74044963117 0.37642798755420565 0.8690801673890045 1.2856570028477385 1.4051771399480248 1.0756048707871448 0.9905066962400013 0.9076774485026683 0.8296653717104517 1.0485292224154346 1.0 15.209710004890718 -4.828490766051492 3.3974984045392933 1.0663604618034745 0.3229247481235977 0.6275691025922954 0.16064958691667158 0.2021577653465363 3.8415347702646514 0.047039736944659016 0.3653614608763202 1.4842574379397551e-05 4.828490766051492 -0.7434357136798768 HNQLPLVIEFTEQTAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HNQLPLVIEFTEQTAPK 17 0 P07237;H7BZ94;I3L398;I3L312;I3NI03;I3L4M2 P07237 P4HB Protein disulfide-isomerase 0 67.646 0.015526 2374100.0 25382.0 26315.0 31816.0 39757.0 33401.0 37342.0 33644.0 34197.0 30989.0 29351.0 False True 29678.671282648724 28927.379290223642 32574.614102851905 37529.544183933096 26856.313821084703 35383.719783165994 30456.996758533467 33299.36498471654 31442.15549957184 34672.10395761182 0.8559812614467299 0.8343127756420159 0.9395049732971443 1.0824132342765995 0.7745798712970443 1.020524160472758 0.8784294369839365 0.9604079702064371 0.9068430210641749 1.0 15.08148776374279 -5.267286917334378 21.9167350953966 0.943016543914881 0.8451470055773466 0.2024918288130465 0.07942699081011528 120.74240435721578 452560.9849504107 0.01957707762112416 0.042834952941183585 5.403971907322945e-06 5.267286917334378 -0.09786953833753442 HNQLPLVIEFTEQTAPK ddPTM_PC-9_Lapatinib_30min_R1 1 HNQLPLVIEFTEQTAPK 17 0 P07237;H7BZ94;I3L398;I3L312;I3NI03;I3L4M2 P07237 P4HB Protein disulfide-isomerase 0 75.877 0.0072899 4451300.0 45770.0 41484.0 47283.0 49133.0 40664.0 40944.0 50097.0 38234.0 36725.0 43063.0 False True 45117.31140680996 41387.94634676938 43395.574257658205 52746.40472288326 38272.22346849997 39192.92056512572 52690.77753349644 40010.491220079275 32588.64376860542 50506.38217215936 0.8932992122266873 0.8194597309641327 0.8592097155115409 1.0443512770938217 0.7577700445469003 0.7759993664074011 1.0432498877843042 0.7921868385602614 0.6452381336188688 1.0 15.624178083183216 HNS(ph)GSSSVDDGSATR ddPTM_PC-9_AZD4547_30min_R2 1 HNSGSSSVDDGSATR 15 0 Q9NV58-3;Q9NV58 Q9NV58-3 RNF19A E3 ubiquitin-protein ligase RNF19A 1 HNS(0.989)GS(0.007)S(0.002)S(0.001)VDDGS(0.001)ATR 92.95200000000001 0.017297999999999997 0.0 0.0 542.72 2841.7 2706.1 2171.7 2364.5 945.94 2542.3 902.92 1104.3 True False 0.0 718.1436265319554 2804.0172012662047 2082.250453828228 1870.1969412706742 2216.6474412127995 1030.1268274714039 2149.4459512421813 950.646507852286 1065.6387931227607 0.0 0.6739090498268168 2.6313017312829605 1.953992729305937 1.7550008064085454 2.080111436931748 0.9666754195881964 2.017049271398444 0.892090747810053 1.0 10.057502792479621 -3.0693003736206164 7.221848656598501 1.4717658721087616 1.2288383173456665 0.0 0.7707839797562919 0.0 0.0 0.1813091963486491 0.0 0.0008525102834171977 3.0693003736206164 -0.24292755476309513 HNS(ph)GSSSVDDGSATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HNSGSSSVDDGSATR 15 0 Q9NV58-3;Q9NV58 Q9NV58-3 RNF19A E3 ubiquitin-protein ligase RNF19A 1 HNS(0.98)GS(0.013)S(0.003)S(0.003)VDDGS(0.002)ATR;HNS(0.983)GS(0.011)S(0.003)S(0.003)VDDGSATR 85.63600000000001 0.025519 0.0 1210.2 1583.52 1197.9099999999999 1792.77 3579.5600000000004 1607.56 1636.5900000000001 1700.7600000000002 966.35 1283.02 True False 1415.062957460463 1740.7214004809025 1226.472717498974 1692.326909138761 2878.1709140864655 1523.2567236523569 1481.5603473144768 1656.116852104177 980.481040595412 1515.6213696192685 0.9336520227449245 1.148519963741459 0.8092210509060517 1.1165895012181584 1.8990039146844941 1.0050377714290255 0.9775266943396634 1.0926982723397478 0.6469168753154447 1.0 10.565693671153676 -6.981003151910151 24.999973115498207 0.9447630707786531 1.1849664529933002 0.1470536473810088 0.28894957246312947 533.4197967232956 701981.6275448265 0.10781164339550489 0.09506769698704841 1.0447126371481453e-07 6.981003151910151 0.2402033822146471 HNS(ph)GSSSVDDGSATR ddPTM_PC-9_Lapatinib_30min_R1 1 HNSGSSSVDDGSATR 15 0 Q9NV58-3;Q9NV58 Q9NV58-3 RNF19A E3 ubiquitin-protein ligase RNF19A 1 HNS(0.996)GS(0.002)S(0.001)SVDDGS(0.001)ATR 133.9 6.636399999999999e-05 0.0 677.94 740.18 904.56 547.94 0.0 760.1 847.13 539.79 1251.7 555.77 True False 668.2724512810303 738.4661586865234 830.1905685025753 588.2373354742565 0.0 727.5922948796417 890.9902463610758 564.8706140002776 1110.7203650146614 651.8341039830244 1.0252186057734007 1.1329050661420366 1.2736224806736958 0.9024341191721013 0.0 1.116223116332358 1.3668972533297823 0.866586468165201 1.7039924088470026 1.0 9.348361025680667 -6.986044851010639 24.999450008958664 1.225867053111835 0.8713863822613874 0.1751967167431614 0.3798315785475818 462.211124008011 828008.5402217845 0.14049291510184028 0.12384908276526592 1.0326547546226403e-07 6.986044851010639 -0.35448067085044754 HNS(ph)ISEAK ddPTM_PC-9_AZD4547_30min_R2 2 HNSISEAK 8 0 Q01970-2;Q01970 Q01970-2 PLCB3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1 HNS(0.989)IS(0.011)EAK;HNS(0.99)IS(0.01)EAK 94.76700000000001 0.0066324 14768000.0 144227.0 96935.0 98338.0 105773.0 83379.0 84815.0 88259.0 75847.0 130667.0 153437.0 True False 190088.18589203723 128267.34308275927 97033.97386709231 81388.66902655967 71803.26507630311 79511.50464219243 96113.8800196617 64126.58894067005 137573.79085803244 148065.21733258828 1.283813911980798 0.8662894999481312 0.6553461752541913 0.5496812181333726 0.48494350239608663 0.537003261634307 0.6491320632297319 0.43309691564243 0.9291432068681621 1.0 17.17587324487168 -4.7965936765979915 1.858436833544225 0.6180736167281915 1.4843159294816344 0.5387399228396643 0.17542092378600577 0.551306700314475 2.0496527667453903 0.045060987037111574 0.8353562583973729 1.597372941207722e-05 4.7965936765979915 0.8662423127534429 HNS(ph)ISEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HNSISEAK 8 0 Q01970-2;Q01970 Q01970-2 PLCB3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1 HNS(0.983)IS(0.017)EAK;HNS(0.995)IS(0.005)EAK;HNS(0.994)IS(0.006)EAK 81.296 0.018084 23084100.0 146684.9 265438.0 165851.0 163249.0 268161.0 191213.0 109466.0 205092.0 187358.0 191732.0 True False 171515.75641116526 291788.93042137084 169805.5168334203 154102.68779039927 215616.77705984536 181185.4536687514 99096.58801479076 199708.5523129368 190097.756303488 226491.49385032261 0.7572723968367299 1.2882997302062045 0.7497213866479093 0.680390619403298 0.951986202194137 0.799965820299142 0.4375289611550664 0.8817485765929675 0.8393152125576712 1.0 17.78909734364698 -5.333463870909452 24.999961609683442 0.7776279846131356 1.0227968683878714 0.1865638359236682 0.1902345888658169 191.4535266200083 66453.46133734872 0.04820993675681232 0.1003570132131978 4.640193902912698e-06 5.333463870909452 0.24516888377473578 HNS(ph)ISEAK ddPTM_PC-9_Lapatinib_30min_R1 4 HNSISEAK 8 0 Q01970-2;Q01970 Q01970-2 PLCB3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1 HNS(0.986)IS(0.014)EAK;HNS(0.949)IS(0.051)EAK;HNS(0.967)IS(0.033)EAK;HNS(0.973)IS(0.027)EAK 96.756 0.0060224 35098000.0 109957.0 165667.0 154520.0 154372.0 180518.0 121814.0 163137.0 167834.0 160301.0 174108.0 True False 108388.99301635586 165283.40824005037 141815.9620644493 165725.03184989607 169900.2861520431 116604.2991823031 171583.43562452868 175632.18034814004 142246.2133356355 204202.33581567305 0.5307921311644307 0.8094099784894059 0.6944874626334444 0.8115726550723239 0.832019308072003 0.5710233368121611 0.8402618654637309 0.8600889879471194 0.69659444769543 1.0 17.639639843347993 -14.522878745279526 0.12615570946484536 1.8180265659569979 0.6366696608616081 0.38431182435097755 0.10547575644264556 163.9439325647529 1.3139685789920559 34.19229671874991 0.861118042285716 3.0000000000056086e-15 14.522878745279526 -1.1813569050953898 HNS(ph)PSGHLTHSR ddPTM_PC-9_AZD4547_30min_R2 2 HNSPSGHLTHSR 12 0 A0A087WVA8;Q8IWB9;Q8IWB9-2;J3KRZ8 A0A087WVA8 TEX2 Testis-expressed sequence 2 protein 1 HNS(0.998)PS(0.002)GHLTHSR;HNS(0.994)PS(0.006)GHLTHSR 69.846 0.026900999999999998 1370990.0 0.0 0.0 3552.1 8213.4 5593.2 2823.39 1211.45 5429.0 1777.58 5106.1 True False 0.0 0.0 3504.9968330990896 6319.927525765032 4816.680725659682 2646.842976970101 1319.2667031103792 4590.0727960090435 1871.539249798506 4927.3369931758825 0.0 0.0 0.711336942846275 1.2826253886263146 0.9775423788408518 0.5371751476783194 0.2677443627130635 0.9315524394548347 0.3798277350200514 1.0 12.266592429289206 -5.271810141657395 6.209256524366278 0.7609275415397129 4.481024855326427e-16 0.5233763364868704 0.2906885930382932 0.11716368536400623 21.59764685070566 0.08093147201032887 0.18703957886273823 5.347981033081198e-06 5.271810141657395 -0.7609275415397124 HNS(ph)SDGFFNNGPLR ddPTM_PC-9_AZD4547_30min_R2 2 HNSSDGFFNNGPLR 14 0 Q9HC44 Q9HC44 GPBP1L1 Vasculin-like protein 1 1 HNS(0.973)S(0.027)DGFFNNGPLR;HNS(0.841)S(0.159)DGFFNNGPLR 98.07700000000001 0.0014413 16897000.0 27221.4 17246.5 31338.0 42716.0 37081.0 39696.0 31557.0 38080.0 28370.0 33621.0 True False 35877.23895970599 22821.093851310736 30922.437644114536 32868.486155621205 31932.943214651157 37213.802844738144 34365.511865990564 32195.6109913473 29869.580281497085 32443.939023435934 1.1058225369548995 0.7034008365884882 0.9531036789884749 1.0130855606613796 0.984249883825276 1.147018640919547 1.0592274828641053 0.9923459345701133 0.9206520903618005 1.0 14.985661367556782 -5.578255242943249 4.883820970599137 1.020997963813913 0.8874797629970954 0.14974337979517993 0.10585969022254108 0.2837240573229948 14.104338143984561 0.028175466683026788 0.05104076356804991 2.6408562208284346e-06 5.578255242943249 -0.13351820081681764 HNS(ph)SDGFFNNGPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HNSSDGFFNNGPLR 14 0 Q9HC44 Q9HC44 GPBP1L1 Vasculin-like protein 1 1 HNS(0.875)S(0.125)DGFFNNGPLR;HNS(0.958)S(0.042)DGFFNNGPLR;HNS(0.711)S(0.289)DGFFNNGPLR;HNS(0.919)S(0.081)DGFFNNGPLR 145.79 1.8412999999999998e-05 18776500.0 42338.2 45284.0 43796.6 42544.9 65652.7 49495.1 54009.4 53338.6 50016.1 39078.4 True False 49505.22104243314 49779.49624847001 44840.877043530425 40161.24718542683 52788.5247268504 46899.48982485617 48893.238637805756 51938.518266918196 50747.49084133514 46163.0045755558 1.0724003235406196 1.0783417740280539 0.971359586660755 0.8699877218714005 1.143524456698881 1.0159540146069772 1.0591433353906012 1.1251113038344267 1.0993108292653662 1.0 15.494449506158215 -6.30754066912138 24.999984967013972 1.0764669971442287 1.0018544125596685 0.22813099077237642 0.06807333282107104 695.2039331926612 376996.026865548 0.022166724207738176 0.025134721806132916 4.925602158254952e-07 6.30754066912138 -0.07461258458456022 HNS(ph)SDGFFNNGPLR ddPTM_PC-9_Lapatinib_30min_R1 2 HNSSDGFFNNGPLR 14 0 Q9HC44 Q9HC44 GPBP1L1 Vasculin-like protein 1 1 HNS(0.908)S(0.092)DGFFNNGPLR;HNS(0.994)S(0.006)DGFFNNGPLR 159.44 1.3212e-05 17952500.0 34909.0 41771.0 43996.0 42277.0 54495.0 48693.0 39639.0 45815.0 54150.0 39198.0 True False 34411.19125847346 41674.28181590257 40378.818709471256 45386.191611937684 51289.71124129221 46610.51389892698 41691.31346488343 47943.73215588042 48051.0567752208 45973.322071948096 0.7485034734844713 0.9064883705963745 0.8783097868428681 0.9872288876776937 1.1156407440172362 1.013860034434355 0.9068588386898964 1.042859858612102 1.04519435641438 1.0 15.488509299860294 -4.93330148948831 0.9384148773486116 1.0180452769109756 0.669896445627684 0.6752603492001505 0.05712246139363837 1.091517653597899 0.8942350405174398 0.021362583198791262 0.3691693540444908 1.1659998928455661e-05 4.93330148948831 -0.34814883128329155 HNS(ph)TTSSTSSGGYR ddPTM_PC-9_AZD4547_30min_R2 6 HNSTTSSTSSGGYR 14 0 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0 A0A0A0MRT6 ABI1 Abl interactor 1 1 HNS(0.972)T(0.017)T(0.001)S(0.002)S(0.006)T(0.002)S(0.001)SGGYR;HNS(0.7)T(0.294)T(0.005)S(0.001)STSSGGYR;HNS(0.983)T(0.017)TSSTSSGGYR;HNS(0.995)T(0.004)TSSTSSGGYR;HNS(0.989)T(0.011)TSSTSSGGYR;HNS(0.76)T(0.228)T(0.012)SSTSSGGYR 165.24 1.5490999999999998e-05 44985950.0 1685.0900000000001 1833.3 12428.470000000003 22304.699999999997 17987.329999999998 11634.34 7642.159999999999 21771.0 13325.429999999998 11715.8 True False 2220.9135679506167 2425.87837286452 12263.660367181963 17162.6960191798 15490.099713416337 10906.842880608898 8322.297435174392 18406.79219781044 14029.785025395478 11305.633408011985 0.19644309060797227 0.21457253081860658 1.0847389018019151 1.5180658526409567 1.370122235030099 0.9647263878978708 0.7361195197852969 1.628108000102503 1.2409552405487483 1.0 13.464754202156241 -5.287660770806891 4.377013524142918 1.21628351948776 0.18814424914616526 0.7139967633161671 0.2507491610631284 0.10302188967372773 4.871449015980091 0.07002314771395582 0.16849493637294977 5.156312489973075e-06 5.287660770806891 -1.0281392703415946 HNS(ph)TTSSTSSGGYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 HNSTTSSTSSGGYR 14 0 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0 A0A0A0MRT6 ABI1 Abl interactor 1 1 HNS(0.912)T(0.027)T(0.06)S(0.001)STSSGGYR;HNS(0.998)T(0.002)TSSTSSGGYR;HNS(0.691)T(0.217)T(0.069)S(0.022)S(0.001)TSSGGYR;HNS(0.983)T(0.015)TSSTSSGGYR;HNS(0.99)T(0.01)TSSTSSGGYR;HNS(0.67)T(0.213)T(0.094)S(0.022)S(0.001)TSSGGYR 167.92 7.2511e-05 36365900.0 10982.970000000001 15234.73 31586.45 30194.7 50913.2 32399.15 27038.699999999997 29101.969999999998 26335.9 18773.8 True False 12842.169897454598 16747.133311577 32339.590760278712 28502.988851538186 40937.12394346428 30700.08153855614 24477.398592764188 28338.074123586004 26721.01271487218 22177.341326680962 0.5790671527431708 0.7551461225619941 1.4582266775761719 1.2852302010271632 1.8458986287149726 1.3842994562031519 1.1037120379851884 1.2777940198581528 1.2048789943420697 1.0 14.436798801644324 -5.168246020526663 4.409526047833186 1.341793808456766 0.6229967313821609 0.5903522872730065 0.21824970318494039 0.15073364201428685 5.027999826270375 0.058474579122863926 0.17060129488223794 6.788189841305243e-06 5.168246020526663 -0.718797077074605 HNS(ph)TTSSTSSGGYR ddPTM_PC-9_Lapatinib_30min_R1 4 HNSTTSSTSSGGYR 14 0 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0 A0A0A0MRT6 ABI1 Abl interactor 1 1 HNS(0.512)T(0.158)T(0.273)S(0.049)S(0.007)T(0.001)SSGGYR;HNS(0.984)T(0.015)T(0.001)SSTSSGGYR;HNS(0.863)T(0.124)T(0.008)S(0.003)S(0.003)TSSGGYR;HNS(0.939)T(0.055)T(0.001)S(0.002)S(0.002)T(0.002)SSGGYR 176.42 0.00010228 26591800.0 5172.32 3327.14 14250.0 7724.7 14068.5 14484.599999999999 11770.0 12066.0 19393.3 9563.9 True False 5098.561768312678 3319.436211748871 13078.420006590719 8292.800206843789 13241.018489735205 13865.127423251755 12379.393008947698 12626.630409098623 17209.02233349751 11217.007371904288 0.4545385056163252 0.29592886067483587 1.165945565779763 0.7393059424758083 1.1804412755313456 1.2360807979836337 1.103627072578635 1.1256683704002082 1.5341901598996603 1.0 13.453400204730013 -5.199416481229882 0.811732844718243 1.2096940074383464 0.09257288570187713 0.6551056378318247 0.2106212214454616 0.8808956019513334 0.6696965447998984 0.08169231319791577 0.7940472914377081 6.318056695692311e-06 5.199416481229882 -1.1171211217364694 HNS(ph)TTSSTSSGGYRR ddPTM_PC-9_AZD4547_30min_R2 1 HNSTTSSTSSGGYRR 15 1 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0 A0A0A0MRT6 ABI1 Abl interactor 1 1 HNS(0.461)T(0.461)T(0.065)S(0.01)S(0.002)TSSGGYRR 72.705 0.0070036000000000005 3604900.0 0.0 759.58 982.68 2095.1 2409.8 676.63 497.54 1190.5 616.72 819.85 True False 0.0 1005.0993806035203 969.6490211282942 1612.1070639723298 2075.240866175841 634.3202191363148 541.820096137305 1006.5355799684597 649.3185601411662 791.1473010429189 0.0 1.2704326732563735 1.2256238754149422 2.0376825678949952 2.6230777295709453 0.8017725881136559 0.6848536238739084 1.2722480107580576 0.8207302979928152 1.0 9.627802519996944 HNS(ph)WSSSSR ddPTM_PC-9_AZD4547_30min_R2 5 HNSWSSSSR 9 0 H3BQ37;H3BPW9;Q96F86 H3BQ37 EDC3 Enhancer of mRNA-decapping protein 3 1 HNS(0.998)WS(0.002)SSSR;HNS(0.971)WS(0.029)SSSR;HNS(0.975)WS(0.024)S(0.001)SSR;HNS(0.999)WSSSSR;HNS(0.941)WS(0.057)S(0.001)S(0.001)S(0.001)R 137.4 0.0009472999999999999 83357920.0 17846.2 11336.340000000002 115029.0 178723.0 122726.5 82510.09999999999 44447.0 120316.7 64411.2 86918.2 True False 23520.92037598009 15000.590210788738 113503.6403013865 137521.17359282437 105688.04388859215 77350.73040355781 48402.69689475181 101724.51861771641 67815.84453392887 83875.220273841 0.28042752435328977 0.17884412299382207 1.3532440204724687 1.6395923986111363 1.2600627878357313 0.9222119495009178 0.5770798185295216 1.2128077671283595 0.8085325357420168 1.0 16.355957029685648 -5.253407461978467 24.862833140508013 1.1047267358430708 0.2296356916036184 0.6006971677895758 0.2827073135494135 405.60852925906687 1255554.8307675803 0.08044317761282818 0.20486947320082322 5.579464748525457e-06 5.253407461978467 -0.8750910442394524 HNS(ph)WSSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 HNSWSSSSR 9 0 H3BQ37;H3BPW9;Q96F86 H3BQ37 EDC3 Enhancer of mRNA-decapping protein 3 1 HNS(0.993)WS(0.007)SSSR;HNS(0.767)WS(0.004)S(0.2)S(0.028)S(0.001)R;HNS(0.976)WS(0.024)SSSR;HNS(0.949)WS(0.033)S(0.009)S(0.009)SR;HNS(0.999)WS(0.001)SSSR;HNS(0.999)WS(0.001)SSSR 161.93 7.4797e-05 58337990.0 16147.600000000002 31885.9 91975.0 59091.2 95992.7 92276.8 76870.40000000001 79549.0 83107.90000000001 55219.9 True False 18881.0697503624 35051.32142542815 94168.03281712998 55780.511640255194 77183.61952436264 87437.64216397752 69588.67921849863 77460.92303913269 84323.19581280032 65230.83074951214 0.2894500887604227 0.5373428641438894 1.4436123491779116 0.855124961606784 1.1832383343506612 1.3404342878866595 1.066806576260246 1.1874894455443068 1.292689282719751 1.0 15.993266381680497 -5.112758169825383 4.709391288226504 1.1676508348438688 0.3423753636696743 0.7792687511924282 0.16326640526902592 0.0874583890821043 2.951841944347343 0.040243578615635545 0.11834515846239144 7.713328542918308e-06 5.112758169825383 -0.8252754711741945 down HNS(ph)WSSSSR ddPTM_PC-9_Lapatinib_30min_R1 4 HNSWSSSSR 9 0 H3BQ37;H3BPW9;Q96F86 H3BQ37 EDC3 Enhancer of mRNA-decapping protein 3 1 HNS(0.998)WS(0.001)SSSR;HNS(0.998)WS(0.002)SSSR;HNS(0.99)WS(0.003)S(0.007)SSR;HNS(0.921)WS(0.06)S(0.009)S(0.009)SR 161.93 0.00015962 43807800.0 32831.1 24021.9 111818.0 33995.9 63289.0 83511.0 51327.6 55724.2 110153.0 52301.4 True False 32362.92249351363 23966.27876645113 102624.75566996197 36496.07189299793 59566.465450961405 79939.42920364914 53985.09198012435 58313.34976319357 97746.40917748667 61341.62730276515 0.5275850008637574 0.39070171138695536 1.6730034754936454 0.5949641947525047 0.9710610570690921 1.3031840320943955 0.8800727068042882 0.9506325855258967 1.5934759717905376 1.0 15.90457881923049 -5.222523477359646 24.99713410066042 1.0928249930487697 0.45914290853174583 0.4152243110521422 0.3126769424104029 520.9437527738424 334620.02647658746 0.07629647494793947 0.20185395430133135 5.990685529177351e-06 5.222523477359646 -0.6336820845170239 HNSIS(ph)EAK ddPTM_PC-9_AZD4547_30min_R2 1 HNSISEAK 8 0 Q01970-2;Q01970 Q01970-2 PLCB3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1 HNS(0.486)IS(0.514)EAK 79.469 0.045110000000000004 0.0 18929.0 14952.0 20742.0 24518.0 22361.0 19084.0 22346.0 19667.0 19352.0 32259.0 True False 24948.02825234096 19784.941597703775 20466.947527417968 18865.753899323925 19256.561128955913 17890.67446314445 24334.75071006196 16627.91705270029 20374.907212108974 31129.62222887541 0.8014240606235019 0.6355663892172625 0.6574749727747453 0.606038639358248 0.6185928305642524 0.5747154376499084 0.7817232901557468 0.5341509424832166 0.6545182932933086 1.0 14.926000448748608 -11.301206378817009 2.3945951519761177 1.1039497148281923 0.6470846121578034 0.6348718576400996 0.0792035302258319 7287691.246114072 4746475.129233334 4428988.794192518 0.019731494136400195 4.997969726218701e-12 11.301206378817009 -0.4568651026703888 HNYEGTLR ddPTM_PC-9_AZD4547_30min_R2 2 HNYEGTLR 8 0 H3BND8;A0A669KBL1;Q93009-3;Q93009 H3BND8 USP7 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 7 0 ; 138.06 1.6361e-08 0.0 10127.1 7916.3 12234.4 14075.3 13440.9 14225.7 10778.2 13824.7 11574.9 11891.4 False True 13347.307143234311 10475.089163316103 12072.163862185049 10830.45704621723 11574.863041822076 13336.16473015899 11737.438919859924 11688.41027500207 12186.725583373307 11475.08570546047 1.1631553337229488 0.912854982715422 1.0520325662091097 0.9438236300983365 1.008695127768338 1.1621843245852985 1.0228628544599552 1.0185902375822857 1.0620160839037742 1.0 13.486217308472284 HNYEGTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HNYEGTLR 8 0 H3BND8;A0A669KBL1;Q93009-3;Q93009 H3BND8 USP7 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 7 0 98.58200000000001 0.0056766 0.0 2762.4 4831.4 5221.1 3436.3 5199.8 3374.6 5456.9 4036.4 3616.9 2924.0 False True 3230.0197601130267 5311.029462389761 5345.590825132017 3243.7752516349137 4180.936517076624 3197.630035356222 4939.982927465261 3930.4487769193174 3669.7903199974594 3454.0980536287348 0.9351268290486715 1.5376024015329297 1.547608302409411 0.9391091976173449 1.2104278605189862 0.92574964164579 1.4301802817310054 1.137908859532852 1.0624453223446066 1.0 11.754093322791235 -7.47991826363923 0.21665973883737122 0.9628998309981182 1.3565408027426218 0.08331891337943054 0.2258838463551268 7.385483341841244 1.3645044565616982 0.7875074179963174 1.1255544578831258 3.3119344785564234e-08 7.47991826363923 0.39364097174450363 HNYEGTLR ddPTM_PC-9_Lapatinib_30min_R1 1 HNYEGTLR 8 0 H3BND8;A0A669KBL1;Q93009-3;Q93009 H3BND8 USP7 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 7 0 104.01 0.0035329999999999997 0.0 6400.9 6692.9 6863.0 5607.6 6639.8 5382.5 4748.1 6310.8 6831.3 5062.4 False True 6309.621992218698 6677.403001260549 6298.750631946118 6020.001610405226 6249.26001834906 5152.3030222203315 4993.933385368276 6604.022806708068 6061.8870572219 5937.429094776014 1.062685868159698 1.1246286725572174 1.0608548803535203 1.0139071160785502 1.0525195195758057 0.8677666612900746 0.841093561818218 1.112269755359024 1.0209615913654262 1.0 12.535622664323423 -5.965037274396044 1.548619844465594 0.9732257836445957 1.0924468704942396 0.2657083193678227 0.07637669810429909 0.5617960918406615 2.73055070974438 0.028392137688530782 0.05070844127149345 1.0838338873101177e-06 5.965037274396044 0.11922108684964394 HPAKPDPSGECNPDLR ddPTM_PC-9_AZD4547_30min_R2 2 HPAKPDPSGECNPDLR 16 1 E9PC52;Q16576;Q16576-2;Q5JP01 E9PC52 RBBP7 Histone-binding protein RBBP7 0 ; 89.506 0.0016844000000000002 6641300.0 34362.0 33018.0 41464.0 46893.0 36587.0 40108.0 32166.0 46747.0 36865.0 38676.0 False True 45288.40122599927 43690.422797818566 40914.16026790367 36082.54333962792 31507.526587590462 37600.040419607954 35028.711686201226 39523.32528919412 38813.60863861089 37321.965012058194 1.2134516821760921 1.1706356507140718 1.0962488243768755 0.9667910928047375 0.8442086738308348 1.007450717224024 0.9385548610552512 1.0589829682446972 1.0399669102650615 1.0 15.187737326042466 -5.513140435725169 2.5492319612660284 0.9758893365501189 1.1937858213502388 0.6941346524508949 0.057185019523327926 0.16853529147754362 2.169397859649131 0.017579642749219478 0.040646835651790385 3.068029733898617e-06 5.513140435725169 0.21789648480011992 HPAKPDPSGECNPDLR ddPTM_PC-9_Lapatinib_30min_R1 3 HPAKPDPSGECNPDLR 16 1 E9PC52;Q16576;Q16576-2;Q5JP01 E9PC52 RBBP7 Histone-binding protein RBBP7 0 ;; 106.42 0.00045999 13417100.0 68925.0 89461.0 107036.0 85462.0 104814.0 87691.0 82301.0 90112.0 102082.0 84251.0 False True 67942.11686070291 89253.85855096743 98235.91325090844 91747.1605728744 98649.04659225266 83940.66034770512 86562.1430781143 94298.9324900295 90584.45018888447 98813.67309259903 0.6875780925280841 0.9032541323236408 0.9941530374936153 0.9284864908006958 0.9983339704395758 0.8494842638735199 0.8760138184216295 0.9543105679480336 0.9167197954881923 1.0 16.59242306445706 -4.770554877831325 4.181930187159975 0.9351053539799977 0.6651475012649088 0.7072809249043011 0.04828939460010827 0.12272931962757187 4.27851216676653 0.012290029673511524 0.10083841931575613 1.6960752711612254e-05 4.770554877831325 -0.2699578527150889 HPASLTSSGSSGS(ph)PSSSIK ddPTM_PC-9_AZD4547_30min_R2 2 HPASLTSSGSSGSPSSSIK 19 0 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 HPASLTSSGSS(0.054)GS(0.93)PS(0.011)S(0.003)S(0.001)IK;HPASLT(0.001)S(0.001)S(0.009)GS(0.034)S(0.098)GS(0.856)PS(0.001)SSIK 183.63 5.1714e-11 8279100.0 18583.4 16619.6 57336.0 90673.0 78090.0 67934.0 44618.0 83736.0 56727.0 67199.0 True False 24492.534641267535 21991.560686008386 56575.68717732315 69769.7407338853 67248.55143151776 63686.07624079096 48588.91556348087 70796.52526185563 59725.47340953421 64846.383463783786 0.37770085751885346 0.3391331869462004 0.8724570925211309 1.0759233901278575 1.0370439774652285 0.9821068321621844 0.7492926045847632 1.0917574964129642 0.9210301364437761 1.0 15.98473849597931 -5.3145897826799775 4.0478496059767455 0.9756769882594885 0.3502059706360689 0.874916980406901 0.09248892418481673 0.06534979939426676 2.229864709539267 0.024997407393349092 0.05918998425858723 4.8462991362997784e-06 5.3145897826799775 -0.6254710176234195 down HPASLTSSGSSGS(ph)PSSSIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HPASLTSSGSSGSPSSSIK 19 0 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 HPASLTSSGSS(0.003)GS(0.995)PS(0.002)SSIK 146.17 9.9109e-05 3349000.0 6444.8 7646.6 20122.0 19814.0 26286.0 18477.0 16183.0 14913.0 16017.0 12383.0 True False 7535.77734939778 8405.703913381118 20601.784793109946 18703.88581785472 21135.446995629867 17508.03359310048 14650.029085226104 14521.549551629607 16251.21832381303 14627.939876225942 0.5151632706424574 0.5746334743310292 1.4083859359165807 1.2786411467450183 1.4448683255787953 1.1968899066611158 1.0015100697150159 0.9927269099068936 1.1109710910300719 1.0 13.836438981586861 -5.246021668678916 23.37179943343683 1.1863077143377943 0.544897936148541 0.729501518945515 0.15446294745673994 187.5497351375141 284304.39607311034 0.04374275724885657 0.11459148019428102 5.675162890574402e-06 5.246021668678916 -0.6414097781892533 HPASLTSSGSSGS(ph)PSSSIK ddPTM_PC-9_Lapatinib_30min_R1 2 HPASLTSSGSSGSPSSSIK 19 0 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 HPAS(0.001)LT(0.005)S(0.013)S(0.013)GS(0.01)S(0.03)GS(0.905)PS(0.013)S(0.006)S(0.003)IK;HPASLTSSGSS(0.378)GS(0.618)PS(0.003)S(0.001)SIK 129.2 2.0442000000000002e-05 6827500.0 36911.0 26871.0 53372.0 31018.0 43701.0 47327.0 29258.0 32368.0 55879.0 28806.0 True False 36384.6423713516 26808.781850449326 48983.960181877905 33299.16719301471 41130.59309947171 45302.934534625456 30772.836079506535 33871.93544519348 49585.31858804366 33785.07871841771 1.0769441348531401 0.7935095275014025 1.4498696477855066 0.9856175701275456 1.2174188919989002 1.3409154648477661 0.910841035357154 1.0025708605713095 1.467669174351 1.0 15.044098596117744 -5.235521573707336 24.99366901475726 1.1636454726736722 0.9352268716943759 0.18315565104971365 0.19929061451617627 1297.4942646159282 1251225.8841672686 0.048801542924875645 0.12901868193693877 5.81404550147433e-06 5.235521573707336 -0.22841860097929634 HPDIY(ph)AVPIK ddPTM_PC-9_AZD4547_30min_R2 2 HPDIYAVPIK 10 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 HPDIY(1)AVPIK;HPDIY(1)AVPIK 104.01 0.0072273 0.0 22984.0 33081.0 34325.0 42480.0 34756.0 34652.0 33486.0 36699.0 31533.0 33812.0 True False 30292.433903101326 43773.7863157864 33869.82807244342 32686.89230945757 29930.729332229846 32485.204962108648 36466.189129022416 31028.01280912432 33199.770004104605 32628.25217157184 0.9284111739670305 1.341591516628199 1.0380521731394898 1.001797219709391 0.9173255488783958 0.9956158482314347 1.1176261890238324 0.9509554065589279 1.0175160419113933 1.0 14.993834086840016 -5.503688961269544 24.71051010938041 1.0009184872825188 1.1487064813847099 0.20403220255707644 0.10447231610045714 828.4556247781177 1066793.0972824842 0.02578779796237434 0.05236421744717292 3.1355305658439206e-06 5.503688961269544 0.14778799410219112 HPDIY(ph)AVPIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HPDIYAVPIK 10 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 HPDIY(1)AVPIK 106.6 0.0033246 3740200.0 9412.7 11421.0 10522.0 10346.0 15190.0 11494.0 14161.0 9939.1 12815.0 8032.3 True False 11006.084200700801 12554.801401240518 10772.884384907216 9766.34716218456 12213.628542327382 10891.234405969417 12819.567563238388 9678.209156346938 13002.395131401881 9488.492406348185 1.1599402443888016 1.3231608208740147 1.1353631244621876 1.0292833406970405 1.287204333341298 1.1478361302879625 1.3510647439272416 1.019994403944701 1.3703330913457605 1.0 13.211963165305212 -10.562886632104515 4.387603604658214 0.9999890427905267 1.199013164414619 0.20296911334670031 0.12029695021122656 79516058.46393314 3.0572148287738106 9811.006644510027 0.027206199553357464 2.735982831939123e-11 10.562886632104515 0.19902412162409222 HPDVEVDGFSELR ddPTM_PC-9_AZD4547_30min_R2 2 HPDVEVDGFSELR 13 0 P09874;Q5VX84;Q5VX85 P09874 PARP1 Poly [ADP-ribose] polymerase 1 0 ; 143.76 5.8525e-05 10065800.0 15453.8 13217.2 23599.0 34053.0 23498.0 26617.0 19296.6 28455.0 18866.6 23949.0 False True 20367.78694099143 17489.401423566775 23286.06184068732 26202.60696360543 20235.708305004522 24952.634782305402 21013.960017532514 24057.933580850502 19863.84995907272 23110.552799508263 0.8813197640787203 0.756771228074601 1.0075943246663832 1.1337940373353146 0.8756046850352749 1.0797073959579337 0.9092798514962238 1.040993427961723 0.8595142717440915 1.0 14.496264148726297 -5.271048404329181 24.76334013580857 0.9913872694313918 0.8190454951671193 0.3753208211427299 0.08727637125439185 499.8689217766818 1288210.236341326 0.021526349014653286 0.04577135509434516 5.357369435781392e-06 5.271048404329181 -0.17234177426427244 HPDVEVDGFSELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HPDVEVDGFSELR 13 0 P09874;Q5VX84;Q5VX85 P09874 PARP1 Poly [ADP-ribose] polymerase 1 0 ; 125.03 0.00012292 4630900.0 11242.4 11994.1 16156.3 14420.9 15142.7 14898.5 17004.0 11899.4 13735.3 12883.7 False True 13145.516272478533 13184.794981754574 16541.52746510896 13612.94372618861 12175.596637781495 14117.196432689701 15393.258021700824 11587.053358456476 13936.152777865336 15219.412822686914 0.8637334715622593 0.8663143010419282 1.0868702792824718 0.894446052865876 0.8000043615107059 0.92757825792371 1.0114225956703642 0.7613337973975028 0.915682683703232 1.0 13.893625079117665 -5.941699358748185 24.999999018061825 0.8928528246310045 0.9415317978735834 0.027249201130932543 0.0927458815318078 268.5019625234569 115134.20792776092 0.026397413005236348 0.039153688436052124 1.1436697685810421e-06 5.941699358748185 0.04867897324257897 HPDVEVDGFSELR ddPTM_PC-9_Lapatinib_30min_R1 2 HPDVEVDGFSELR 13 0 P09874;Q5VX84;Q5VX85 P09874 PARP1 Poly [ADP-ribose] polymerase 1 0 ; 93.649 0.0033713999999999997 7417900.0 12518.400000000001 10357.2 15538.3 15324.9 12865.599999999999 16276.0 13858.4 9877.5 15428.4 11353.8 False True 12339.8853204066 10333.218539744474 14260.800953572527 16451.944268367763 12108.8707027428 15579.91342120912 14575.920142328023 10336.444709586573 13690.691123745462 13316.289202012467 0.9266759780601411 0.7759833376240306 1.070929050671062 1.2354751401675332 0.9093277052673809 1.1699891151999429 1.094593239994006 0.7762256100614309 1.028116085198601 1.0 13.700904487806115 -5.26939094459772 24.843012921362504 1.0371278126649073 0.8513296560241052 0.25498017188481203 0.12595842469031285 685.3943615765243 2141377.5477295145 0.0339213431666673 0.07270685694828101 5.377854591220381e-06 5.26939094459772 -0.18579815664080213 HPELADK ddPTM_PC-9_AZD4547_30min_R2 1 HPELADK 7 0 P46783;F6U211;A0A2R8Y7H1;S4R435;A0A2R8YFH6;A0A1W2PQS6;A0A2R8Y6L3;Q9NQ39 P46783 RPS10;RPS10-NUDT3;RPS10P5 40S ribosomal protein S10;Putative 40S ribosomal protein S10-like 0 83.265 0.017852 7936100.0 121860.0 117780.0 117760.0 109160.0 108560.0 128310.0 121930.0 123000.0 139130.0 126350.0 False True 160608.94515453896 155850.08168656717 116198.42545698278 83994.84850518813 93488.31788200242 120286.75541637298 132781.53379029137 103993.17625881608 146484.12776047568 121926.5249579467 1.317260089303243 1.2782295053543182 0.9530200708751472 0.6888972562300002 0.7667594718560804 0.9865511664329046 1.089029100403613 0.8529167569951168 1.2014131282015874 1.0 16.895652490981263 -5.259656127045478 4.99939813017003 0.9272660859559244 1.3046104393785336 0.5035230271137976 0.14091677018478999 0.13963544067702902 11.118107307633172 0.03885657134456719 0.09637181285345993 5.499761708400973e-06 5.259656127045478 0.3773443534226092 HPELADK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HPELADK 7 0 P46783;F6U211;A0A2R8Y7H1;S4R435;A0A2R8YFH6;A0A1W2PQS6;A0A2R8Y6L3;Q9NQ39 P46783 RPS10;RPS10-NUDT3;RPS10P5 40S ribosomal protein S10;Putative 40S ribosomal protein S10-like 0 ;; 85.212 0.016312 11961900.0 273566.0 352940.0 304154.0 316521.0 441070.0 345357.0 318894.0 328065.0 359719.0 383035.0 False True 319875.32062520966 387977.5507007985 311406.18487046903 298787.35454492696 354645.4997474869 327245.8709537478 288686.051727374 319453.6413635996 364979.20985351136 452476.2133966076 0.7069439478906493 0.8574540256787504 0.6882266418666148 0.6603382580092266 0.7837881622224206 0.7232333131883509 0.6380137633319808 0.706012011030489 0.8066262911672601 1.0 18.787482426374638 -8.63558252834592 3.0058017149590364 0.9998046015311586 0.7219875492114742 0.6742128335788532 0.05898564436925406 0.28208143021380727 5.519780104158996 0.059023121811645686 0.01570816440886983 2.3142883633904744e-09 8.63558252834592 -0.27781705231968434 HPELADK ddPTM_PC-9_Lapatinib_30min_R1 2 HPELADK 7 0 P46783;F6U211;A0A2R8Y7H1;S4R435;A0A2R8YFH6;A0A1W2PQS6;A0A2R8Y6L3;Q9NQ39 P46783 RPS10;RPS10-NUDT3;RPS10P5 40S ribosomal protein S10;Putative 40S ribosomal protein S10-like 0 ; 95.90899999999999 0.01089 23011400.0 186704.0 214870.0 217350.0 210644.0 231900.0 202920.0 255430.0 245230.0 229890.0 222160.0 False True 184041.5667226793 214372.48171657356 199480.32199526258 226135.4624477847 218260.09793294178 194241.5846296236 268654.9155714116 256624.28105612955 203997.36735097918 260560.0599904071 0.7063306890912409 0.8227373056502443 0.7655828832807559 0.8678822934570639 0.8376575363890281 0.7454772025949598 1.0310671389210706 0.9848949262046437 0.7829187917691208 1.0 17.9912564314442 -7.254175797960061 24.986984555697394 0.9484614591106733 0.7968574418185651 0.5122496566657386 0.07576527444777346 487.11019510179943 1675680.6515136908 0.029229670734249483 0.02216529062956973 5.569602514877178e-08 7.254175797960061 -0.15160401729210815 HPEPVPEEGS(ph)EDELPPQVHK ddPTM_PC-9_AZD4547_30min_R2 1 HPEPVPEEGSEDELPPQVHK 20 0 Q7Z3C6;H7C152;Q7Z3C6-2 Q7Z3C6 ATG9A Autophagy-related protein 9A 1 HPEPVPEEGS(1)EDELPPQVHK 61.61600000000001 0.042621 0.0 7837.6 9318.4 8668.2 8345.4 9334.5 8911.0 11103.0 12661.0 10822.0 9544.6 True False 10329.79376779268 12330.390568756215 8553.254004298731 6421.496965144705 8038.565800198517 8353.793761322591 12091.145490638939 10704.53337083635 11394.028826449125 9210.446459150142 1.1215301900518102 1.3387397259669813 0.9286470576897473 0.6971971438762615 0.872766139605815 0.906991186406984 1.3127643208464623 1.1622165568534306 1.2370767125115523 1.0 13.169055374615043 -7.252574984831526 24.833789303786038 1.1915324457908398 0.9743165613217417 0.24004838576135135 0.173930370402088 923.566209078894 2587395.5049142754 0.07514139586610523 0.0573303860759857 5.590169999464306e-08 7.252574984831526 -0.21721588446909812 HPEPVPEEGS(ph)EDELPPQVHKV ddPTM_PC-9_AZD4547_30min_R2 5 HPEPVPEEGSEDELPPQVHKV 21 1 Q7Z3C6;H7C152;Q7Z3C6-2 Q7Z3C6 ATG9A Autophagy-related protein 9A 1 HPEPVPEEGS(1)EDELPPQVHKV;HPEPVPEEGS(1)EDELPPQVHKV;HPEPVPEEGS(1)EDELPPQVHKV;HPEPVPEEGS(1)EDELPPQVHKV;HPEPVPEEGS(1)EDELPPQVHKV 90.978 0.00019131 46191300.0 149840.0 156817.0 216897.0 257342.0 218172.0 181765.0 184793.0 230368.0 189707.0 182732.0 True False 197486.00313438437 207505.02852642545 214020.80406201773 198015.77779426612 187882.58372284682 170399.20581604794 201239.2190085245 194769.91893000732 199734.52472548367 176334.60829929233 1.1199503321502937 1.1767685908498895 1.2137197917425302 1.1229547035836231 1.065488990136038 0.9663401158712404 1.141234956367508 1.1045473194883262 1.1327017801660053 1.0 17.42795612732386 -6.027617398123381 4.320988866920638 1.0730247971564206 1.1711197278715748 0.40580590689297846 0.055267603175709765 0.22420813422157523 9.778446401289559 0.017037494835254754 0.023721982975817523 9.383883380282901e-07 6.027617398123381 0.09809493071515418 HPEPVPEEGS(ph)EDELPPQVHKV ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 HPEPVPEEGSEDELPPQVHKV 21 1 Q7Z3C6;H7C152;Q7Z3C6-2 Q7Z3C6 ATG9A Autophagy-related protein 9A 1 HPEPVPEEGS(1)EDELPPQVHKV;HPEPVPEEGS(1)EDELPPQVHKV;HPEPVPEEGS(1)EDELPPQVHKV;HPEPVPEEGS(1)EDELPPQVHKV;HPEPVPEEGS(1)EDELPPQVHKV 99.11 0.00010957 41403100.0 131763.0 127879.0 136608.0 149213.0 176802.0 138080.0 151981.0 132599.0 134160.0 126196.0 True False 154067.87346212458 140573.98199713143 139865.25280872482 140853.079365073 142158.91728377622 130838.84172405244 137584.25943284592 129118.41675025363 136121.8361942162 149074.33583301352 1.0334969637879494 0.942979093025081 0.938224893152606 0.9448512956841236 0.9536109383912758 0.8776751611398244 0.9229238464423664 0.8661344424494795 0.9131138195825594 1.0 17.18567238361176 -1.5228787470809109 0.737614996196473 0.9161381852652242 18.92744833022256 0.41950741901946464 0.036469966611958775 319.18704157896565 1.4521510365494077 0.013446386418976405 9536.601664001137 0.029999999875620804 1.5228787470809109 18.011310144957335 HPEPVPEEGS(ph)EDELPPQVHKV ddPTM_PC-9_Lapatinib_30min_R1 4 HPEPVPEEGSEDELPPQVHKV 21 1 Q7Z3C6;H7C152;Q7Z3C6-2 Q7Z3C6 ATG9A Autophagy-related protein 9A 1 HPEPVPEEGS(1)EDELPPQVHKV;HPEPVPEEGS(1)EDELPPQVHKV;HPEPVPEEGS(1)EDELPPQVHKV;HPEPVPEEGS(1)EDELPPQVHKV 115.31 1.5852e-06 33815400.0 239577.0 230790.0 231713.0 190523.0 194904.0 196164.0 163525.0 169081.0 228783.0 131226.0 True False 236160.58804695884 230255.6199346958 212662.45157804605 204534.69698609613 183440.12991600728 187774.52300061824 171991.52436603003 176937.12052053725 203015.0493482059 153908.23925234596 1.534424597371639 1.4960577877651609 1.3817483236187729 1.3289392301522187 1.1918798552119176 1.2200420452653322 1.1174939379563362 1.149627345358902 1.3190655050984312 1.0 17.231710940737926 -1.5228787452808172 0.2357868153239479 1.0719890997058148 4.048415527824913 0.8032355797307329 0.071316430833093 21.254985078552384 0.28163164104517124 0.1009773142329992 24.61250247896761 0.029999999999966866 1.5228787452808172 2.9764264281190984 HPGCT(ph)TPVTVK ddPTM_PC-9_Lapatinib_30min_R1 1 HPGCTTPVTVK 11 0 Q96Q89-3;Q96Q89;Q96Q89-2;Q96Q89-5;Q96Q89-4 Q96Q89-3 KIF20B Kinesin-like protein KIF20B 1 HPGCT(0.5)T(0.5)PVT(0.001)VK 86.014 0.021455000000000002 0.0 13481.0 13910.0 15312.0 14720.0 16188.0 14025.0 10679.0 12069.0 16238.0 11176.0 True False 13288.758467887383 13877.792249627846 14053.10646602927 15802.557904480518 15235.853666832532 13425.183443871822 11231.906367251695 12629.769800050663 14409.105446279507 13107.756708916075 1.0138087517941332 1.0587465542588217 1.0721213994207075 1.2055882829844868 1.1623540171804454 1.0242167093885584 0.8568900550016769 0.9635340417525236 1.0992808125953573 1.0 13.678133180147457 -6.982551202455423 10.408187681479392 0.9717023804106457 1.1031240096714814 0.3784714953325089 0.07432422720089531 0.36924206357801737 211.82212270420013 0.02827880115226877 0.02471273441442708 1.0409953691051257e-07 6.982551202455423 0.13142162926083567 HPGSFDVVHVK ddPTM_PC-9_Lapatinib_30min_R1 1 HPGSFDVVHVK 11 0 P62701;C9JEH7;P22090 P62701 RPS4X;RPS4Y1 40S ribosomal protein S4, X isoform;40S ribosomal protein S4, Y isoform 1 0 115.91 0.00055204 5207000.0 35435.0 33006.0 48916.0 35534.0 45265.0 45068.0 45789.0 44753.0 47312.0 36413.0 False True 34929.69040201686 32929.57663488261 44894.31530122048 38147.28889794909 42602.60169441404 43140.54669863924 48159.730372702325 46832.38775885885 41983.22434255305 42706.93853272734 0.8178926329558699 0.7710591713252377 1.051218299499902 0.8932339851220175 0.9975569113146956 1.0101531081554727 1.1276792958548498 1.0965990391226494 0.9830539435736023 1.0 15.382182860953591 -5.050455161660989 0.6378150596386101 1.0537973015181052 0.6628411417505364 0.5955423483139914 0.06946379650520838 1.7079540097555532 0.6630294485259939 0.03473224503368352 0.46418928676552984 8.903173532711168e-06 5.050455161660989 -0.3909561597675688 HPHDIIDDINSGAVECPAS ddPTM_PC-9_Lapatinib_30min_R1 2 HPHDIIDDINSGAVECPAS 19 0 P30050;P30050-2 P30050 RPL12 60S ribosomal protein L12 0 ; 96.773 0.00053737 22139000.0 42662.0 41469.0 46705.0 33654.0 52770.0 46725.0 48859.0 40246.0 50731.0 42382.0 False True 42053.63205674736 41372.981078347766 42865.09518651367 36129.02742645294 49666.172349811764 44726.68067129494 51388.67995107691 42115.9760852464 45017.14055888692 49707.67222953482 0.8460189377317158 0.8323258608308994 0.8623436436245852 0.7268300003995389 0.9991651212406121 0.8997943107205023 1.0338178724962157 0.8472731511298238 0.9056376720078851 1.0 15.601180924158927 -6.27249013574156 24.997314566655984 0.9418974851802888 0.8212303421067587 0.5142790432342947 0.062036587697020654 636.3861159103883 1439532.0485655991 0.018867097318998344 0.02158899543535582 5.33961401458974e-07 6.27249013574156 -0.1206671430735301 HPLLSS(ph)GGPQSPLR ddPTM_PC-9_Lapatinib_30min_R1 1 HPLLSSGGPQSPLR 14 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 HPLLS(0.092)S(0.663)GGPQS(0.245)PLR 127.07 2.9933000000000003e-05 5069000.0 1334.8 1490.3 2791.2 1088.8 2418.9 2743.2 560.08 1357.0 823.15 785.39 True False 1315.765507227659 1486.8493019137582 2561.7183103435814 1168.873984130325 2276.625057740376 2625.879730711529 589.0782019075128 1420.0511739720569 730.4381788462232 921.1436150336071 1.4284043071607835 1.61413408034046 2.7810194507510313 1.2689378345065983 2.471520206604608 2.8506735408633608 0.6395074473658712 1.5416175619045545 0.7929688345281248 1.0 9.847282293479271 -7.2753278608861125 24.99605345239549 1.038658248217873 2.06271274507912 0.478926245727173 0.548795665494629 768.3889354335494 1382916.8629063424 0.23027678288722497 0.15615263474920274 5.304838161591193e-08 7.2753278608861125 1.024054496861247 HPLLSSGGPQS(ph)PLR ddPTM_PC-9_AZD4547_30min_R2 4 HPLLSSGGPQSPLR 14 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 HPLLS(0.002)S(0.252)GGPQS(0.745)PLR;HPLLSS(0.002)GGPQS(0.998)PLR;HPLLS(0.018)S(0.05)GGPQS(0.932)PLR;HPLLS(0.001)S(0.002)GGPQS(0.997)PLR 117.27 7.5063e-05 30179000.0 7962.5 7930.9 24805.8 40293.200000000004 23000.3 20037.2 21706.0 28093.899999999998 22522.800000000003 30686.5 True False 10494.409369711288 10494.408327797546 24476.858884178208 31004.225263734374 19807.105359077184 18784.270716459763 23637.791949906226 23752.63328859798 23713.30922679248 29612.174975243677 0.35439508845550205 0.3543950532701858 0.826580921686479 1.047009390213805 0.668883841718357 0.6343428246038584 0.7982457205412252 0.8021239003367912 0.8007959309512808 1.0 14.853902838006851 -5.260171197927544 24.681551982066694 0.81016262588785 0.354395012013024 0.7085567946406053 0.11982105400297831 50.08211850905815 974671.745660239 0.03224036695161483 0.07619949218131317 5.493242887478758e-06 5.260171197927544 -0.45576761387482606 HPLLSSGGPQS(ph)PLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HPLLSSGGPQSPLR 14 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 HPLLSSGGPQS(1)PLR;HPLLS(0.001)S(0.008)GGPQS(0.991)PLR;HPLLSS(0.001)GGPQS(0.999)PLR;HPLLS(0.107)S(0.394)GGPQS(0.498)PLR 155.26 2.7142000000000003e-10 15925500.0 16583.0 18067.399999999998 20529.5 25572.2 30914.5 31397.5 24020.499999999996 24369.800000000003 20334.6 17065.5 True False 19390.174370820427 19861.012068713164 21019.00113856232 24139.472540191 24857.02564659512 29750.959827860166 21745.104346639906 23730.118571937444 20631.955055716317 20159.34005957633 0.9618456910552226 0.9852015001492347 1.0426433145353695 1.1974336693985168 1.2330277465996333 1.4757903651576882 1.0786615178064962 1.1771277483195626 1.023443971615305 1.0 14.299160790790042 -5.626009584287447 3.177238521426101 1.1888262817356585 0.9783105568916746 0.2813329704111399 0.12664015995742411 0.299621214567325 5.980732971895806 0.0368454088429383 0.07058234315284653 2.3658674854379594e-06 5.626009584287447 -0.21051572484398395 HPLLSSGGPQS(ph)PLR ddPTM_PC-9_Lapatinib_30min_R1 2 HPLLSSGGPQSPLR 14 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 HPLLS(0.006)S(0.011)GGPQS(0.983)PLR;HPLLSSGGPQS(1)PLR 126.8 1.7440999999999998e-05 14104000.0 10894.8 5873.6 12323.7 7560.6 18073.2 17859.8 6258.4 12571.900000000001 17484.1 5652.1 True False 10739.438154138374 5860.0000400729095 11310.492956857684 8116.6317454222435 17010.16990927832 17095.977987227234 6582.429329413615 13156.03636997738 15514.856542264793 6629.057954050156 1.62005495027795 0.8839868471043649 1.7061991364771991 1.2244019891941396 2.5660010860043267 2.57894532009365 0.992966025495666 1.984601199924559 2.3404315741101165 1.0 12.694588150236093 -6.220623795841551 24.997644222646414 1.9472677908629454 1.349579478720084 0.18518165172783574 0.563791451111266 844.4635772050032 517194.3952700661 0.16643232996765195 0.21486120898205607 6.016947250945058e-07 6.220623795841551 -0.5976883121428613 HPPDDDLSQDSPEQEAS(ph)KSPR ddPTM_PC-9_Lapatinib_30min_R1 2 HPPDDDLSQDSPEQEASKSPR 21 1 Q9P0K8-2;Q9P0K8 Q9P0K8-2 FOXJ2 Forkhead box protein J2 1 HPPDDDLSQDS(0.024)PEQEAS(0.488)KS(0.488)PR;HPPDDDLSQDS(0.003)PEQEAS(0.499)KS(0.499)PR 69.111 0.0013282 19825100.0 117512.0 109386.0 123443.0 125935.0 149525.0 134876.0 121697.0 113371.0 134555.0 114816.0 True False 115836.25733093824 109132.72343765589 113293.99304375982 135196.68000684484 140730.23347746054 129107.66789131238 127997.87519200571 118638.63054118348 119399.99897303485 134661.79261729645 0.860201361347835 0.8104208425904951 0.8413224779038618 1.0039720798242195 1.0450643106869248 0.9587550067615045 0.9505136735834987 0.8810118166059903 0.8866657472202599 1.0 17.038981049657252 -5.744703733712199 23.02929194364028 0.9588871759856914 0.8346252639577291 0.5736438559865262 0.04876976118131375 77.85736893016131 107133.94759695606 0.014968052013691363 0.02580536323252214 1.8000984845627047e-06 5.744703733712199 -0.12426191202796233 HPPLYQAGLTPPLS(ph)PPK ddPTM_PC-9_AZD4547_30min_R2 2 HPPLYQAGLTPPLSPPK 17 0 Q9ULL5;Q9ULL5-2;A0A3Q5ADB5 Q9ULL5 PRR12 Proline-rich protein 12 1 HPPLYQAGLTPPLS(1)PPK;HPPLYQAGLTPPLS(1)PPK 134.52 1.7719e-05 64485000.0 152039.0 143220.0 124430.0 165566.0 159372.0 154098.0 152117.0 156622.0 137642.0 158457.0 True False 200384.23939234312 189513.06418025238 122779.97689888238 127397.31666920093 137245.94876096613 144462.22769972932 165655.11831032406 132419.66871551462 144917.47511828784 152909.46866055683 1.3104763305219205 1.2393808299795466 0.8029586262669005 0.8331551851246686 0.8975634404017053 0.9447565867907141 1.0833542210395175 0.8660004503022148 0.9477338217686807 1.0 17.2223182203551 -5.172147921295045 5.687948452098874 0.9201597936819402 1.2882957020999262 0.7674531061285265 0.07790459706298195 0.10563770103779223 5.274954063762239 0.021152830020612988 0.058348958492734346 6.727474785452856e-06 5.172147921295045 0.36813590841798594 HPPLYQAGLTPPLS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HPPLYQAGLTPPLSPPK 17 0 Q9ULL5;Q9ULL5-2;A0A3Q5ADB5 Q9ULL5 PRR12 Proline-rich protein 12 1 HPPLYQAGLTPPLS(1)PPK;HPPLYQAGLTPPLS(1)PPK 116.73 7.6961e-05 31217200.0 139997.0 133844.0 93774.0 140906.0 143580.0 120294.0 145091.0 119172.0 101693.0 111431.0 True False 163695.72703321162 147131.14777581932 96009.92779987531 133011.49364341548 115446.52969765392 113985.5708745158 131346.93011212625 116043.86127317155 103180.06774074542 131632.55821268953 1.243580837870787 1.1177413078767902 0.7293782716335588 1.010475641053013 0.8770362839193437 0.865937518971104 0.9978301105407238 0.8815741549721305 0.7838491414413515 1.0 17.0061568462037 -5.059183197937363 5.576461018272596 0.8957593284229238 1.2170455800193525 0.6432507735432478 0.08780671819855249 0.10466091274925599 6.825018513632491 0.021380640878841877 0.06211998026081652 8.726032015459005e-06 5.059183197937363 0.32128625159642865 HPPLYQAGLTPPLS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 4 HPPLYQAGLTPPLSPPK 17 0 Q9ULL5;Q9ULL5-2;A0A3Q5ADB5 Q9ULL5 PRR12 Proline-rich protein 12 1 HPPLYQAGLTPPLS(1)PPK;HPPLYQAGLTPPLS(1)PPK;HPPLYQAGLTPPLS(1)PPK;HPPLYQAGLTPPLS(1)PPK 127.88 3.3428e-05 75298600.0 211411.0 190760.0 167405.0 179695.0 174816.0 197335.0 193044.0 179246.0 171849.0 168949.0 True False 208396.24037197127 190318.30694025935 153641.60710198715 192910.36974494712 164533.6665814799 188895.44206035274 203038.87374845383 187574.42352969458 152493.55596980473 198151.6095396083 1.0517009720797408 0.9604681353961793 0.7753740050810736 0.9735493453379519 0.8303423169953683 0.9532874474208833 1.0246642670236228 0.9466207413884294 0.7695802033812043 1.0 17.596245160467817 -4.882933698488982 4.291840447509112 0.9100407191957194 1.0495688971459256 0.20450287489737695 0.08548840700179093 0.33769700225837956 10.093623463008626 0.021233366349216028 0.1088612710026087 1.309381804345726e-05 4.882933698488982 0.13952817795020622 HPQGEQMYR ddPTM_PC-9_AZD4547_30min_R2 2 HPQGEQMYR 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 72.243 0.022262999999999998 2094210.0 0.0 0.0 0.0 842.16 748.54 678.63 577.2 500.56 0.0 1044.8600000000001 False True 0.0 0.0 0.0 648.0130232422971 644.618141740918 636.1951588201492 628.5696818154372 423.2099537244959 0.0 1008.2797694306323 0.0 0.0 0.0 0.6426916842814618 0.6393246807926423 0.6309708655360641 0.6234080072541628 0.41973464762015333 0.0 1.0 9.97768028656349 -5.755469716463175 24.998924352240834 0.5492428421062595 1.7460371569005296e-07 0.5485114539124654 0.23465922779081957 112.72839262292435 472062.07805371814 0.06466646860816556 0.10835791945647251 1.7560233381757629e-06 5.755469716463175 -0.5492426675025438 HPQGEQMYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HPQGEQMYR 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 63.283 0.039447 937850.0 0.0 716.8 0.0 400.86 0.0 0.0 0.0 570.14 0.0 0.0 False True 0.0 787.959166833833 0.0 378.4011138056549 0.0 0.0 0.0 555.174429113264 0.0 0.0 0.0 HPQGEQMYR ddPTM_PC-9_Lapatinib_30min_R1 4 HPQGEQMYR 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ;;; 81.95 0.010870999999999999 3554350.0 5608.33 5062.629999999999 5412.54 6530.98 7153.94 6706.630000000001 8516.71 8922.0 10408.3 7018.15 False True 5528.354185758239 5050.907791282061 4967.541854208599 7011.290055910604 6733.159314387192 6419.803068818117 8957.663571217921 9336.548691362337 9236.007649742027 8231.227876402949 0.6716317745991176 0.6136275009177987 0.6034994934898361 0.851791514120314 0.8180018115753572 0.7799326133616379 1.088253624577385 1.1342838312286423 1.1220692451267875 1.0 13.006891942412816 -6.846507400836917 0.8530607360329512 1.1194590646862548 0.6416684993932426 0.8261654626267231 0.08182312553358632 0.24035695009185665 0.37591172286730734 0.057232491286460345 0.04925587379802835 1.4239429809463234e-07 6.846507400836917 -0.4777905652930122 HPRPTAS(ph)PDPGTR ddPTM_PC-9_Lapatinib_30min_R1 1 HPRPTASPDPGTR 13 1 A0A3B3ISX9 A0A3B3ISX9 1 HPRPTAS(0.978)PDPGT(0.022)R 58.674 0.030412 2407800.0 5631.5 3135.0 8686.8 4829.0 4781.6 6520.3 3301.3 4190.2 8589.8 5745.8 True False 5551.193777309379 3127.7411001138257 7972.604836017703 5184.140769071763 4500.355688987299 6241.441968561674 3472.2251606150394 4384.891989077166 7622.326269395972 6738.95387420275 0.8237471098533244 0.46412858115664907 1.183062680772674 0.769279752591432 0.6678122113604334 0.9261737185135528 0.5152469100444496 0.6506784392549235 1.1310844994168667 1.0 12.718308935766887 -8.265291799607613 24.925774081198455 1.065542281105825 0.7508697340822418 0.29187796372370034 0.19658060089372706 424.55024038031314 2746845.1247061417 0.16491620957853317 0.04885646322260454 5.428854477609051e-09 8.265291799607613 -0.31467254702358327 HPS(ph)LIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HPSLIK 6 0 A0AVK6 A0AVK6 E2F8 Transcription factor E2F8 1 HPS(1)LIK 64.265 0.045810000000000003 2841500.0 20412.0 21582.0 22941.0 23012.0 20546.0 16396.0 14417.0 16354.0 15002.0 10469.0 True False 23867.3484446232 23724.518329530936 23488.000444226975 21722.712245910607 16520.158790695077 15536.164896491613 13051.317389958886 15924.72482849531 15221.375869004374 12366.9468274416 1.9299305461282341 1.9183812027789662 1.8992562005771987 1.7565137579235854 1.3358316342104521 1.2562651973256396 1.0553386839990857 1.287684426131694 1.230811135633651 1.0 13.594201748853541 -6.266512287338987 1.7496948312103382 1.1705271005404732 1.9271377451302065 0.9472355004358703 0.08042376938127574 0.07379263532282777 0.44602853923407176 0.028159889970937484 0.03730653949670034 5.413619311058451e-07 6.266512287338987 0.7566106445897334 HPS(ph)SPSALR ddPTM_PC-9_AZD4547_30min_R2 1 HPSSPSALR 9 0 O60504-2;O60504;H0YAZ3;H0YB51 O60504-2 SORBS3 Vinexin 1 HPS(0.86)S(0.14)PSALR 117.71 0.001842 34441000.0 3041.7 1446.9 13104.0 29404.0 17590.0 15332.0 6049.9 23392.0 6674.6 15238.0 True False 4008.8973287096783 1914.5821293283568 12930.232397998501 22625.36208727143 15147.932125501287 14373.287616271788 6588.3293797907345 19777.30389468476 7027.405729534032 14704.522258086236 0.27263023295470384 0.13020362686557188 0.8793371298335092 1.538666927776549 1.030154659881671 0.9774739610032351 0.4480478361796293 1.344981057362059 0.4779077896032669 1.0 13.843972292160272 -5.3043895415214495 5.523376559524311 0.983593835077535 0.19926956544961621 0.48107018531382306 0.31620516343211924 0.14687466616147632 11.612983545659008 0.08262542676043803 0.18237129781063988 4.9614710142639185e-06 5.3043895415214495 -0.7843242696279187 HPS(ph)SPSALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HPSSPSALR 9 0 O60504-2;O60504;H0YAZ3;H0YB51 O60504-2 SORBS3 Vinexin 1 HPS(0.943)S(0.057)PSALR 84.31 0.013306 14158000.0 2338.6 5014.6 9557.0 8664.9 15484.0 16317.0 13056.0 10983.0 13229.0 8664.7 True False 2734.478790544572 5512.41634766314 9784.875125124328 8179.433744984825 12450.021352824042 15461.307795563163 11819.24116274559 10694.707887450413 13422.44909819083 10235.541520272536 0.2671552633662476 0.5385563955502731 0.9559704394481116 0.7991207625688022 1.2163519954626243 1.5105510309288925 1.1547255354625228 1.0448599975163455 1.3113570075023677 1.0 13.32129981097233 -5.109226688191908 0.8706235175653874 1.2119453066098886 2.9679653755641213e-09 0.7825255034386445 0.16279227275903363 0.7055562061905826 0.5807573211068412 0.06431823398850585 0.742646233022077 7.77630546165042e-06 5.109226688191908 -1.2119453036419232 down HPS(ph)SPSALR ddPTM_PC-9_Lapatinib_30min_R1 2 HPSSPSALR 9 0 O60504-2;O60504;H0YAZ3;H0YB51 O60504-2 SORBS3 Vinexin 1 HPS(0.848)S(0.152)PSALR;HPS(0.844)S(0.155)PSALR 102.95 0.004752 19383000.0 14747.2 4364.4 28951.0 13780.2 22949.0 28312.0 18455.3 19337.2 28580.0 11429.3 True False 14536.902223694731 4354.294499947935 26570.76053409179 14793.641877399627 21599.184939469942 27101.1617584955 19410.825131523576 20235.676905919274 25361.0194392578 13404.83927641503 1.0844518105690006 0.324830041611095 1.9821767338039904 1.1036045693907055 1.6112975690407827 2.021744625180123 1.448046092255332 1.5095799724747667 1.8919301392802907 1.0 13.710466301107218 -5.260781822841173 24.99984656384771 1.5856932853894843 0.7046409178218062 0.4740819891805512 0.36475685610511166 44.16640157456134 1679087.8092301004 0.08883878057220743 0.20828292901570028 5.4855247282549495e-06 5.260781822841173 -0.8810523675676781 HPSGGS(ph)SPPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HPSGGSSPPPR 11 0 H0YDE2;A0A1B0GTN9;E9PKC0;Q6IQ23-3;Q6IQ23;Q6IQ23-2 H0YDE2 PLEKHA7 Pleckstrin homology domain-containing family A member 7 1 HPS(0.004)GGS(0.498)S(0.498)PPPR 76.07300000000001 0.021165 0.0 629.04 0.0 864.55 884.97 2281.9 1189.0 799.85 472.71 2192.4 665.17 True False 735.524047893679 0.0 885.1641508241332 835.3880000114511 1834.7780757562102 1126.6467468851265 724.0824175874741 460.30186337764553 2224.459702386695 785.7600555171769 0.9360669872809542 0.0 1.1265069337757694 1.0631591592698229 2.3350360747831393 1.4338305173117798 0.9215057605732995 0.5858046106386522 2.8309656195523774 1.0 9.617945019352922 -5.574634343952252 2.5590088186118503 1.4578480652991226 0.4756288094739665 0.24574922073697547 0.6741854155160183 0.3909874589493241 5.132145542536804 0.19103711599950055 0.41190460457234773 2.6629662116852375e-06 5.574634343952252 -0.9822192558251561 HPSGGSS(ph)PPPR ddPTM_PC-9_AZD4547_30min_R2 1 HPSGGSSPPPR 11 0 H0YDE2;A0A1B0GTN9;E9PKC0;Q6IQ23-3;Q6IQ23;Q6IQ23-2 H0YDE2 PLEKHA7 Pleckstrin homology domain-containing family A member 7 1 HPS(0.135)GGS(0.09)S(0.776)PPPR 103.21 0.0029980000000000002 1052200.0 0.0 719.47 4717.3 9005.6 5682.7 4346.3 606.99 6438.2 1225.8 4376.7 True False 0.0 952.0246074973202 4654.745519770935 6929.498055133029 4893.7551955421395 4074.525173923954 661.0109341045601 5443.324125117968 1290.5932854797013 4223.473065163798 0.0 0.22541273326680916 1.1021132248159398 1.6407108434736244 1.1587040144536462 0.9647333156997254 0.1565088551308008 1.2888265276309654 0.3055763030963353 1.0 12.044214135055412 -5.17392771570677 4.634747546517332 0.9657755091900316 0.06324040421617563 0.3984623152143809 0.4147066095542424 0.2241602362518145 8.30790339965231 0.11094945126406547 0.31824083359540734 6.699961147832455e-06 5.17392771570677 -0.902535104973856 HPSGGSS(ph)PPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HPSGGSSPPPR 11 0 H0YDE2;A0A1B0GTN9;E9PKC0;Q6IQ23-3;Q6IQ23;Q6IQ23-2 H0YDE2 PLEKHA7 Pleckstrin homology domain-containing family A member 7 1 HPS(0.132)GGS(0.132)S(0.737)PPPR 80.014 0.016638 518980.0 0.0 629.8 4353.5 2898.3 2590.5 2306.0 883.45 643.45 2910.2 920.39 True False 0.0 692.3223817968026 4457.303950740692 2735.9176474153805 2082.9101210598474 2185.069300519007 799.7632203758883 626.5601192916292 2952.75616944251 1087.2494211967687 0.0 0.6367650037787486 4.099614921693314 2.5163661567222286 1.9157610760253379 2.0097222016580467 0.7355839467778833 0.5762800210111451 2.7158038550090198 1.0 10.086467225437604 -7.236727829174036 23.285052484080502 1.2216068948468803 1.9410544740427162 0.05900700057779873 1.157539846056871 962.8873541099389 907303.7742697975 0.47152293377588506 0.3650010734975739 5.7979193616381897e-08 7.236727829174036 0.7194475791958359 HPSGGSS(ph)PPPR ddPTM_PC-9_Lapatinib_30min_R1 1 HPSGGSSPPPR 11 0 H0YDE2;A0A1B0GTN9;E9PKC0;Q6IQ23-3;Q6IQ23;Q6IQ23-2 H0YDE2 PLEKHA7 Pleckstrin homology domain-containing family A member 7 1 HPS(0.184)GGS(0.184)S(0.633)PPPR 68.786 0.036344 587160.0 813.72 562.67 3503.2 1022.6 2125.4 2126.0 2329.2 1070.7 2714.7 1130.5 True False 802.1162035820277 561.3671721853419 3215.180418743059 1097.8054152935981 2000.3881506971736 2035.0759359480585 2449.794579136873 1120.4486307825202 2408.94189894168 1325.9054187034383 0.6049573312449331 0.4233840244308568 2.4248942446340433 0.8279666104442864 1.5086959616269546 1.5348575450714246 1.847639012994193 0.8450441599960969 1.8168278558641908 1.0 10.372762151489523 -5.206945615938995 24.99754145101248 1.4636431217927137 0.5141689763665112 0.3995486505959207 0.47132760736601437 289.46376113455904 132782.46604487012 0.11115721090527027 0.2940940573023831 6.209467867575436e-06 5.206945615938995 -0.9494741454262026 HPSS(ph)PSALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HPSSPSALR 9 0 O60504-2;O60504;H0YAZ3;H0YB51 O60504-2 SORBS3 Vinexin 1 HPS(0.022)S(0.977)PSALR 115.29 0.0011265999999999997 17261000.0 0.0 1310.1 2644.7 6461.4 2428.1 1939.8 2552.2 2044.0 2546.3 2324.7 True False 0.0 1440.1580698507307 2707.759678080603 6099.388706141439 1952.3312352616929 1838.0734731772648 2310.437139672128 1990.3471657970174 2583.5348203736717 2746.149707684925 0.0 0.5244280986650292 0.986020416331677 2.2210692625652158 0.7109340141938432 0.6693274835066468 0.8413369210012538 0.724777371105136 0.9407844055784046 1.0 11.423194561511748 -4.986611054627584 2.792958269126909 1.0124536624335394 3.5924239955275597e-09 0.36515733058938793 0.42340672787283257 0.35808660907863415 5.0617336504885335 0.11976526842260413 0.6742855078862192 1.0313093267950821e-05 4.986611054627584 -1.0124536588411155 HPT(ph)TPSSTAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HPTTPSSTAK 10 0 O60885 O60885 BRD4 Bromodomain-containing protein 4 1 HPT(0.499)T(0.499)PS(0.001)STAK;HPT(0.986)T(0.013)PS(0.001)STAK 127.51 0.00075883 6494900.0 35965.0 43317.8 60425.0 52911.9 89236.0 79618.0 64019.0 55754.0 67475.0 52347.0 True False 42053.16415887089 47618.10490663309 61865.7611630886 49947.4177856943 71750.8463859858 75442.6919205215 57954.656862577394 54290.51657624601 68461.69422484146 61837.09672137603 0.6800636897355148 0.7700572541623275 1.0004635476636576 0.8077257897592778 1.16032042560599 1.2200231886766806 0.9372150365290914 0.8779603095026728 1.107129827477418 1.0 15.916184965241728 -5.0738995524071075 1.0477752366744242 1.032565176922278 0.585021409047983 0.5104067913944406 0.11652883577048016 1.0572121929024534 1.3114709905804323 0.04150391419609189 0.47419354758448556 8.435298344854084e-06 5.0738995524071075 -0.44754376787429484 HPTT(ph)PSSTAK ddPTM_PC-9_AZD4547_30min_R2 2 HPTTPSSTAK 10 0 O60885 O60885 BRD4 Bromodomain-containing protein 4 1 HPT(0.003)T(0.988)PS(0.007)S(0.002)TAK;HPT(0.007)T(0.99)PS(0.002)S(0.001)TAK 117.25 0.0023779 10267800.0 22108.0 19681.3 43435.0 63657.0 47664.0 46027.0 31267.0 47437.0 43880.0 48841.0 True False 29137.884125033237 26042.895336201665 42859.02352007519 48981.86214084607 41046.67634052834 43148.92441391478 34049.702427795 40106.70164381673 46199.40721720452 47131.09145604341 0.6182306249412566 0.5525629585830926 0.9093577550616976 1.0392685725627375 0.8709044300153823 0.9155087030852536 0.722446719901475 0.8509605953263792 0.9802320674090941 1.0 15.524391471044629 -5.2642782986701 24.963255865559564 0.9023259204384921 0.5853967735893729 0.6992707238781646 0.0852786476654097 127.77563058215628 1123571.1238345557 0.02335718206670068 0.05234487100451875 5.441538438458976e-06 5.2642782986701 -0.3169291468491192 HPTT(ph)PSSTAK ddPTM_PC-9_Lapatinib_30min_R1 1 HPTTPSSTAK 10 0 O60885 O60885 BRD4 Bromodomain-containing protein 4 1 HPT(0.005)T(0.995)PSSTAK 86.11399999999999 0.024059 2023500.0 24123.0 17406.0 25594.0 17650.0 21037.0 21277.0 23170.0 19102.0 24785.0 19179.0 True False 23779.0015963836 17365.697476421454 23489.76011569706 18948.039878673975 19799.645020333322 20367.03230910952 24369.62922831931 19989.548655279465 21993.45230237946 22494.064595588872 1.0571233800514073 0.77201243032915 1.0442648110961434 0.8423573160001382 0.8802164204781411 0.9054402872615354 1.0833804235228452 0.8886588090975542 0.9777446938910461 1.0 14.457256753963009 HPVSTS(ph)ENAR ddPTM_PC-9_Lapatinib_30min_R1 1 HPVSTSENAR 10 0 A0A2R8YH03;Q5VWN6 A0A2R8YH03 FAM208B Protein FAM208B 1 HPVS(0.037)T(0.028)S(0.935)ENAR 68.847 0.022625 684410.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HQAFEAELHANADR ddPTM_PC-9_AZD4547_30min_R2 1 HQAFEAELHANADR 14 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 101.61 0.0007013 6615300.0 11901.0 14210.0 13044.0 21563.0 17339.0 15103.0 15253.0 22498.0 13953.0 13633.0 False True 15685.270443822172 18803.104608304606 12871.028037201799 16591.983495029042 14931.779142925925 14158.607022472794 16610.48745102367 19021.451052608492 14690.527094385941 13155.712819562248 1.1922782641240488 1.429272960439271 0.9783603681332167 1.261199884992711 1.1350034276153176 1.0762326007465945 1.2626064188877892 1.4458700424293258 1.116665230981742 1.0 13.683401800108475 -5.23614253038493 24.999666751814427 1.178883041939916 1.3107755578369762 0.14283918533154316 0.142018690893442 1676.7412710727951 1657037.555682798 0.035880060157047866 0.09484817555483496 5.8057384868435044e-06 5.23614253038493 0.13189251589706008 HQAS(ph)INELKR ddPTM_PC-9_Lapatinib_30min_R1 1 HQASINELKR 10 1 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 HQAS(1)INELKR 54.005 0.044181 4834900.0 18630.0 20108.0 21044.0 23501.0 17363.0 9578.1 9579.7 8621.3 18748.0 12427.0 True False 18364.332783676422 20061.441161431834 19313.84355218914 25229.341937037792 16341.742476971398 9168.466990641627 10075.68999216791 9021.877071603007 16636.402814807756 14574.990392063344 1.2599893577752561 1.3764291173979832 1.325135937153433 1.7310023031491095 1.1212180617196235 0.6290547536576229 0.6912999405923808 0.6189971196492708 1.1414349078313584 1.0 13.83120731194077 -6.539078537827869 5.478731004802171 0.7896185921120962 1.4160609839466505 0.6893653503703056 0.19162527645895386 0.09386229456874436 8.849659537439464 0.06279512851007175 0.06483354907657468 2.890157178988221e-07 6.539078537827869 0.6264423918345543 HQEHILR ddPTM_PC-9_AZD4547_30min_R2 1 HQEHILR 7 0 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 0 75.21300000000001 0.025338 0.0 463.06 0.0 1242.6 2050.5 1241.1 1070.9 1209.9 2138.6 1150.5 1823.2 False True 610.3034477536585 0.0 1226.122312099584 1577.7889049091987 1068.7946879454037 1003.9364537089396 1317.578756113128 1808.128510139057 1211.3130812076984 1759.3703229388902 0.34688742886954826 0.0 0.6969097387362103 0.8967918148543201 0.6074870503442765 0.5706225918554443 0.7488922252094238 1.027713430517982 0.6884923915189696 1.0 10.7808434666397 -5.34245692139417 5.780474763468938 0.7741863065087373 0.17626880228889485 0.6857165564874415 0.16452908403566063 0.11499812580342314 6.324626587666026 0.04349430710736045 0.09296757312872374 4.545096187624344e-06 5.34245692139417 -0.5979175042198425 HQEHILR ddPTM_PC-9_Lapatinib_30min_R1 1 HQEHILR 7 0 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 0 66.07300000000001 0.039463 0.0 551.82 721.88 662.26 983.86 1005.5 1030.2 1087.0 815.07 0.0 0.0 False True 543.9509456086055 720.2085312121752 607.811539197528 1056.2163464607472 946.3584668890601 986.1407475134937 1143.2795412681514 852.9411277593246 0.0 0.0 0.0 HQEVQDQDPVFQGS(ph)DSSGYQSDHKK ddPTM_PC-9_AZD4547_30min_R2 1 HQEVQDQDPVFQGSDSSGYQSDHKK 25 1 Q3B726 Q3B726 TWISTNB DNA-directed RNA polymerase I subunit RPA43 1 HQEVQDQDPVFQGS(0.598)DS(0.102)S(0.102)GY(0.094)QS(0.102)DHKK 50.827 0.0081328 10368000.0 40921.0 42195.0 57766.0 75716.0 67922.0 68835.0 58290.0 64177.0 57647.0 67406.0 True False 53933.02679032411 55833.708581802515 56999.985096366145 58260.84600053879 58492.202719061876 64530.736568358254 63477.69707730737 54259.91929074829 60694.10273131702 65046.13645678965 0.8291503497083487 0.8583708675594133 0.8763008566116975 0.8956849580027193 0.8992417675401586 0.9920763950557805 0.9758872784008593 0.8341758980073062 0.9330931249335047 1.0 15.989175747327826 -5.772990977431295 1.1203645425020785 0.9365957882618811 0.8378178011370313 0.43166261941109885 0.0453051811441367 0.6241475453714523 1.520594589846096 0.017719528985697324 0.0484896501922216 1.6865880642834314e-06 5.772990977431295 -0.09877798712484975 HQEVQDQDPVFQGS(ph)DSSGYQSDHKK ddPTM_PC-9_Lapatinib_30min_R1 1 HQEVQDQDPVFQGSDSSGYQSDHKK 25 1 Q3B726 Q3B726 TWISTNB DNA-directed RNA polymerase I subunit RPA43 1 HQEVQDQDPVFQGS(0.225)DS(0.199)S(0.199)GY(0.177)QS(0.199)DHKK 60.993 0.0010417999999999998 7379700.0 45225.0 41571.0 46868.0 40053.0 46095.0 42607.0 40172.0 43079.0 41672.0 36396.0 True False 44580.08320675073 41474.74490361463 43014.693955711875 42998.63123289117 43383.78272625683 40784.79793176804 42251.90959689441 45080.607607621394 36978.46053438599 42687.00010537842 1.0443480004849013 0.971601302533062 1.0076766661870007 1.0073003754478753 1.0163230636764895 0.9554383730664008 0.9898074236322549 1.056073453190293 0.8662698349169499 1.0 15.38150915808332 -8.254436337152333 24.99970380040036 0.9331349159023855 1.0031284377774026 0.330493562688425 0.041354627465895674 553.4534616316637 1975755.4114508647 0.027272712986928235 0.009820386869500139 5.566262236285806e-09 8.254436337152333 0.06999352187501706 HQEVQDQDPVFQGSDSSGYQS(ph)DHKK ddPTM_PC-9_Lapatinib_30min_R1 1 HQEVQDQDPVFQGSDSSGYQSDHKK 25 1 Q3B726 Q3B726 TWISTNB DNA-directed RNA polymerase I subunit RPA43 1 HQEVQDQDPVFQGS(0.033)DS(0.025)S(0.091)GY(0.394)QS(0.457)DHKK 70.994 0.00015597 8054500.0 81250.0 70626.0 89410.0 82149.0 88150.0 84284.0 76952.0 91626.0 92537.0 76026.0 True False 80091.3601005749 70462.4698362484 82059.05493258082 88190.51150103046 82965.19030956796 80679.36979560017 80936.19803097231 95883.27845715801 82114.50860219036 89166.9928017227 0.8982175756299312 0.7902304162363438 0.9202851005085757 0.9890488478975218 0.9304473292494515 0.9048120527626613 0.9076923588860634 1.0753225542816058 0.9209070085472694 1.0 16.4442221420059 -3.3616915074095477 0.2459935885340947 1.0009477269624028 0.5534369938699177 0.33220390449908066 0.058486777925756746 23.397727520231165 0.6864230279619444 0.08304662213591275 3.5800544072157696 0.00043481897965655164 3.3616915074095477 -0.447510733092485 HQGVMVGMGQK ddPTM_PC-9_AZD4547_30min_R2 8 HQGVMVGMGQK 11 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5;Q562R1;P63261;I3L3I0;I3L1U9;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTBL2;ACTG1;ACTA1;ACTC1;ACTG2;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle 0 ;;;;;;; 129.16 0.00022973 185802000.0 1030308.3 977540.1 1233809.2 1499988.0 1342571.0 1237378.8 1098328.5 1301402.0 1050499.6 1186857.7 False True 1357924.9076560545 1293510.8204864578 1217448.0838513894 1154188.9411835847 1156178.1911123618 1160005.308027476 1196077.6087557618 1100300.224142892 1106026.8642185605 1145306.173174368 1.1856435767672373 1.1294017711450215 1.0629891922061945 1.007755802087923 1.0094926738304926 1.0128342404829336 1.04433001128482 0.9607040020514899 0.9657040974057272 1.0 20.127301892950825 -4.941189603900886 0.8544753045744005 0.9946575046781984 1.2725376877593675 0.8930311565954512 0.02213972194293217 0.6229553306304074 0.4150385828653625 0.0090247092181492 0.1558241233050837 1.145012943570731e-05 4.941189603900886 0.27788018308116913 HQGVMVGMGQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HQGVMVGMGQK 11 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5;Q562R1;P63261;I3L3I0;I3L1U9;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTBL2;ACTG1;ACTA1;ACTC1;ACTG2;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle 0 ;;; 99.28299999999999 0.0031390999999999997 142868900.0 444069.0 423203.0 503799.0 550708.0 573215.0 524072.0 577022.0 502402.0 515517.0 417201.0 False True 519241.11093745613 465215.79698880983 515811.4788283464 519853.616179425 460897.6356083084 496588.7417439716 522362.2988824899 489214.47983891936 523055.46086265275 492836.2387387009 1.053577375450986 0.9439561469331493 1.0466184064476372 1.054820192423083 0.9351942884473514 1.0076140971590772 1.0599104891705082 0.9926511919881326 1.0613169644368905 1.0 18.910748817170948 -7.034069904577287 24.525601452585203 1.0287008418374404 1.0045351142937826 0.05306156214492941 0.04398166262484855 1571.7175768121504 1131414.652264162 0.016475930941446237 0.012770249156861679 9.245493453538823e-08 7.034069904577287 -0.024165727543657756 HQGVMVGMGQK ddPTM_PC-9_Lapatinib_30min_R1 9 HQGVMVGMGQK 11 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5;Q562R1;P63261;I3L3I0;I3L1U9;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTBL2;ACTG1;ACTA1;ACTC1;ACTG2;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle 0 ;;;;;;;; 132.32 9.5961e-05 444528900.0 2764565.0 2239256.0 2461888.0 2378130.0 2431523.0 2232101.0 2373759.6 2077539.4 2256794.0 2060484.0 False True 2725141.7961408743 2234071.1403114833 2259481.071802498 2553025.6134091136 2288505.5976981497 2136639.2435115706 2496661.2571930727 2174069.4649544563 2002610.0946256258 2416635.913977654 1.1276592309080748 0.9244549943952133 0.9349695826060584 1.0564378351917187 0.9469798840866315 0.8841378343975598 1.0331143565121075 0.8996263989870339 0.8286767911718386 1.0 21.204568704957808 -4.757227554591021 24.915378403790978 0.9462643355123668 1.1276595095524988 0.4099343187987685 0.06560031672949504 125.2132173749413 740606.0825694851 0.016485018775748036 0.1244839598573719 1.7489300724461173e-05 4.757227554591021 0.18139517404013206 HQHMHDRDDLYAEQMER ddPTM_PC-9_AZD4547_30min_R2 2 HQHMHDRDDLYAEQMER 17 1 Q9Y5B9 Q9Y5B9 SUPT16H FACT complex subunit SPT16 0 ; 52.42 0.032674 6293400.0 8382.0 5859.1 14172.4 19696.0 12384.4 10635.2 10721.8 11784.5 9586.9 12028.7 False True 11047.301643569235 7752.939494054721 13984.464715918335 15155.391500166577 10665.039830304613 9970.179262755913 11676.019429121197 9963.476305870061 10093.643961955742 11607.578874251325 0.9517317748385123 0.6679204662785266 1.204770165028951 1.3056462216927285 0.9187996864671312 0.8589370247461685 1.0058961955470052 0.8583595609220181 0.8695735838888944 1.0 13.502779463693708 -6.47366594575373 24.99993167198726 0.9122376561611404 1.0304588701596287 0.10354984180918192 0.16364068453880973 991.8297933570539 503846.0370462324 0.05536336320307448 0.06277499974179117 3.35995959042169e-07 6.47366594575373 0.11822121399848828 HQHMHDRDDLYAEQMER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HQHMHDRDDLYAEQMER 17 1 Q9Y5B9 Q9Y5B9 SUPT16H FACT complex subunit SPT16 0 ; 52.372 0.014731000000000001 22115700.0 25818.7 21782.1 39431.7 35117.8 31275.1 33160.5 31394.8 44323.0 31777.8 19726.5 False True 30189.29596743055 23944.482935116124 40371.90127355503 33150.26351944375 25146.968665183864 31421.50500427603 28420.85726533129 43159.5682141004 32242.49020730883 23302.758295111915 1.2955245720315944 1.0275385699785944 1.73249452971512 1.4225896822865598 1.079141290774097 1.3484028202303904 1.219634899242506 1.8521227258814994 1.3836340659325361 1.0 14.508213113105182 HQHMHDRDDLYAEQMER ddPTM_PC-9_Lapatinib_30min_R1 2 HQHMHDRDDLYAEQMER 17 1 Q9Y5B9 Q9Y5B9 SUPT16H FACT complex subunit SPT16 0 ; 42.338 0.029296 2862900.0 13039.5 7275.9 9491.0 7140.2 8480.8 8109.2 3255.2 6069.700000000001 10850.099999999999 6593.6 False True 12853.554338848566 7259.053100579968 8710.686616319474 7665.314127008948 7981.976017894323 7762.388419468482 3423.7383281840716 6351.720420529252 9628.047481381778 7733.294974580259 1.6621057881664756 0.9386753155596483 1.1263874771299882 0.991209329555543 1.0321571909685965 1.0037621020514353 0.4427269798240048 0.8213472318601173 1.2450123153235029 1.0 12.91686752813113 -2.644720351157829 1.2985413945665505 0.9262573470112945 199.99772322554605 0.502906918953703 0.2061356775164255 350.237799321481 2.850262453518905 0.06265643007918628 205381.64110419754 0.002266103016202409 2.644720351157829 199.07146587853475 HQNS(ph)LPELEAAEAGAPGSGPVDLFR ddPTM_PC-9_AZD4547_30min_R2 2 HQNSLPELEAAEAGAPGSGPVDLFR 25 0 Q96BZ8 Q96BZ8 LENG1 Leukocyte receptor cluster member 1 1 HQNS(1)LPELEAAEAGAPGSGPVDLFR;HQNS(1)LPELEAAEAGAPGSGPVDLFR 116.45 4.4595e-09 8871100.0 12951.5 9448.099999999999 14485.3 22303.0 21756.0 15833.2 15760.099999999999 26198.0 16517.300000000003 16298.699999999999 True False 17069.80759206478 12502.013557334469 14293.215457473121 17161.387927915068 18735.554935895754 14843.147501040608 17162.718368640806 22149.701070150124 17390.370757263732 15728.087473938178 1.0853072644941646 0.7948845387623008 0.9087700892532119 1.0911299899845994 1.1912163489007181 0.9437350552402549 1.0912145800994462 1.4082895397709807 1.1056888376339462 1.0 13.9410556301113 -5.82354154516678 4.499567860024008 1.1333947751255675 0.9153048154048175 0.2934982513022607 0.1338085582352949 0.2405203065252275 9.648737898777798 0.03921423123908692 0.06131758132684826 1.501268785588578e-06 5.82354154516678 -0.21808995972075007 HQNS(ph)LPELEAAEAGAPGSGPVDLFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HQNSLPELEAAEAGAPGSGPVDLFR 25 0 Q96BZ8 Q96BZ8 LENG1 Leukocyte receptor cluster member 1 1 HQNS(1)LPELEAAEAGAPGSGPVDLFR;HQNS(1)LPELEAAEAGAPGSGPVDLFR 74.81 0.00010071 7175100.0 10477.5 11176.1 9084.3 11523.9 14700.4 16388.0 14442.1 18767.5 12954.0 7583.8 True False 12251.133809942161 12285.58934772824 9300.9041643996 10878.253243987889 11819.962147704367 15528.584430574796 13074.039736250623 18274.87301080995 13143.42774343971 8958.682906672228 1.3675150619314576 1.3713611114171935 1.0381999520791716 1.214269257804181 1.3193861498213229 1.7333557390461327 1.459370743718741 2.03990622295597 1.4671160794909681 1.0 13.129070929480092 -6.63230090514195 5.619675154716159 1.5985959325567611 1.2448120227512702 0.20749597954112142 0.2614288612426174 0.2647931159602426 12.132007940272812 0.0836680342490282 0.08345826324278065 2.3318418632056594e-07 6.63230090514195 -0.3537839098054909 HQNS(ph)LPELEAAEAGAPGSGPVDLFR ddPTM_PC-9_Lapatinib_30min_R1 1 HQNSLPELEAAEAGAPGSGPVDLFR 25 0 Q96BZ8 Q96BZ8 LENG1 Leukocyte receptor cluster member 1 1 HQNS(1)LPELEAAEAGAPGSGPVDLFR 74.529 0.00010361 3793300.0 16754.0 16584.0 16312.0 18399.0 18858.0 17044.0 18299.0 16031.0 16534.0 24752.0 True False 16515.084887692698 16545.600766917923 14970.8903261409 19752.12383726475 17748.809516254503 16315.067851504567 19246.432682305338 16775.85878404278 14671.76680926132 29030.350220033153 0.5688903083331055 0.5699414799171179 0.5156978890254601 0.680395644129511 0.6113880604859694 0.5620003798729899 0.662976248527096 0.5778731106201453 0.5053940685543877 1.0 14.825274356187029 -11.387586547573354 2.5812895097936095 1.1849883302634792 0.5865865980787507 0.847023467276957 0.05304591768708023 35406639.38198932 22119814.936358716 40205088.42490788 0.01339360825550672 4.096504652425875e-12 11.387586547573354 -0.5984017321847285 HQNVQLPR ddPTM_PC-9_AZD4547_30min_R2 2 HQNVQLPR 8 0 A6NLN1;P26599;P26599-2;P26599-3;A0A0D9SF20;A0A087WUW5;K7EK45;A0A0U1RRM4 A6NLN1;A0A0U1RRM4 PTBP1 Polypyrimidine tract-binding protein 1 0 ; 173.68 0.0010626 9239000.0 17398.3 15281.599999999999 18391.8 29665.0 22013.0 20539.1 17278.3 24719.0 18754.1 16680.8 False True 22930.597492878856 20221.07835202447 18147.912715011364 22826.19256968122 18956.874922038656 19254.78683011791 18816.035227497698 20899.246536111183 19745.40343874603 16096.810269240374 1.4245429441817592 1.2562164810170633 1.127422912456791 1.4180568813251233 1.177678968998201 1.1961864809273524 1.1689294284255516 1.2983470753859758 1.2266656007294692 1.0 13.974487212941273 -14.522878745280046 0.14919877319808186 0.13885903115690704 1.3263820624475815 0.43669655293947796 0.09180219463066229 138.56824291370722 1.2265791052304365 35.61129350667865 0.4751095499673893 3.0000000000020134e-15 14.522878745280046 1.1875230312906744 HQNVQLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HQNVQLPR 8 0 A6NLN1;P26599;P26599-2;P26599-3;A0A0D9SF20;A0A087WUW5;K7EK45;A0A0U1RRM4 A6NLN1;A0A0U1RRM4 PTBP1 Polypyrimidine tract-binding protein 1 0 ;; 133.6 0.0025922 6667100.0 16627.7 17040.4 16478.3 24212.800000000003 24231.2 22676.2 21908.4 18644.8 22186.7 14904.3 False True 19442.44119795517 18732.058295919705 16871.20516630076 22856.235314956746 19483.27030512464 21487.020152831356 19833.077748919706 18155.393755798545 22511.138514387385 17606.331607626125 1.1042868912870947 1.0639387416630262 0.9582464730468356 1.2981827120112086 1.1066058926599749 1.2204143731749504 1.1264741679822203 1.0311854939693739 1.2785819906195994 1.0 14.103806725243423 -5.740175054638276 24.999920259055777 1.15287564820547 1.0443355697714303 0.21124356422034174 0.09689424625694798 372.0665268166152 437425.5478599728 0.0250147998488681 0.04327611420824749 1.8189675246677409e-06 5.740175054638276 -0.10854007843403979 HQNVQLPR ddPTM_PC-9_Lapatinib_30min_R1 1 HQNVQLPR 8 0 A6NLN1;P26599;P26599-2;P26599-3;A0A0D9SF20;A0A087WUW5;K7EK45;A0A0U1RRM4 A6NLN1;A0A0U1RRM4 PTBP1 Polypyrimidine tract-binding protein 1 0 138.83 0.0024142 5843300.0 14272.0 12605.0 14299.0 10649.0 13846.0 13907.0 12408.0 11945.0 13964.0 8897.0 False True 14068.478662835743 12575.813896948885 13123.391415736189 11432.162984022625 13031.605502283373 13312.230028800384 13050.425527189716 12500.008307366408 12391.227272561093 10434.834595492683 1.348222488252244 1.205176160854624 1.2576520782998157 1.0955768277305264 1.2488559720833872 1.2757490218915966 1.2506595488180365 1.1979114947126976 1.1874866974809042 1.0 13.349120111800556 -8.94447376821418 1.1862301656514875 1.0000463362969612 1.234657416884032 0.5782164379871897 0.060445501113948835 1.157860755643081 2.4295134194243717 0.05849431202110606 0.017839780204857936 1.1363869344095952e-09 8.94447376821418 0.23461108058707092 HQPAS(ph)ASSTAASPAHPAK ddPTM_PC-9_AZD4547_30min_R2 1 HQPASASSTAASPAHPAK 18 0 Q96L91-5;Q96L91-2;Q96L91;Q96L91-3 Q96L91-5 EP400 E1A-binding protein p400 1 HQPAS(0.369)AS(0.229)S(0.145)T(0.145)AAS(0.112)PAHPAK 75.112 0.0033911 1850600.0 10599.0 13297.0 29279.0 45762.0 33645.0 34473.0 21935.0 39143.0 25333.0 28339.0 True False 13969.261527104542 17594.995212992722 28890.741329441258 35212.2779158521 28973.972504973917 32317.397860405523 23887.172506274463 33094.34876665722 26672.050661655485 27346.860235720284 0.5108177467795 0.6434009265169776 1.0564555155660746 1.2876168456756898 1.0594990523675663 1.181758987387984 0.8734886674512344 1.2101699603316656 0.9753240566467895 1.0 14.739087582498522 -5.21510429067864 3.524937309353514 1.093763084622434 0.5414309396056942 0.7558351565990319 0.11542740023678005 0.10418695164485522 2.6515228498485723 0.02939957515524314 0.08761142487257347 6.09390541743484e-06 5.21510429067864 -0.5523321450167398 HQPASASSTAAS(ph)PAHPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HQPASASSTAASPAHPAK 18 0 Q96L91-5;Q96L91-2;Q96L91;Q96L91-3 Q96L91-5 EP400 E1A-binding protein p400 1 HQPASASS(0.002)T(0.002)AAS(0.996)PAHPAK;HQPAS(0.001)AS(0.012)S(0.147)T(0.065)AAS(0.775)PAHPAK;HQPAS(0.066)AS(0.051)S(0.04)T(0.04)AAS(0.802)PAHPAK;HQPASASST(0.001)AAS(0.999)PAHPAK 123.84 2.5657e-05 2060000.0 28163.5 29283.6 43496.5 45874.899999999994 54668.9 49519.0 45185.3 39956.1 45247.0 30183.5 True False 32931.02429551955 32190.68227942974 44533.621521394845 43304.6780814325 43956.921488982334 46922.13646678266 40905.02127075742 38907.2947119874 45908.65177608593 35655.529617545486 0.9235881404301101 0.902824404088763 1.2489962145866036 1.214529093970406 1.2328220043421223 1.3159848407830987 1.1472279814525246 1.0911994613268001 1.2875605065615139 1.0 15.12183821311011 -5.256805772611992 24.94314787714403 1.200597277067127 0.9132062357822667 0.6088010738281341 0.08928767293305 226.24050002852843 1217863.0939793806 0.0222173783554279 0.05481937967158483 5.535976366132849e-06 5.256805772611992 -0.28739104128486026 HQPASASSTAAS(ph)PAHPAK ddPTM_PC-9_Lapatinib_30min_R1 1 HQPASASSTAASPAHPAK 18 0 Q96L91-5;Q96L91-2;Q96L91;Q96L91-3 Q96L91-5 EP400 E1A-binding protein p400 1 HQPAS(0.014)AS(0.014)S(0.046)T(0.046)AAS(0.881)PAHPAK 63.398 0.010288 1046600.0 6064.3 5025.2 8516.2 4395.0 5634.8 5758.5 5254.9 5104.4 6357.5 4303.8 True False 5977.82196994358 5013.564458147368 7816.030909482661 4718.222961290207 5303.372142443037 5512.222378719138 5526.973009576827 5341.5690585283455 5641.451402557088 5047.706095546976 1.184265061552839 0.9932362073477837 1.5484322505182833 0.9347261651094475 1.0506499471357111 1.0920252238104655 1.094947468207916 1.058217130201105 1.1176267587239095 1.0 12.301412196004572 HQPS(ph)TPDPFLKPR ddPTM_PC-9_Lapatinib_30min_R1 1 HQPSTPDPFLKPR 13 1 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 HQPS(0.5)T(0.5)PDPFLKPR 70.72800000000001 0.011603 5294500.0 12302.0 11079.0 9914.1 9285.7 10807.0 13072.0 10949.0 11631.0 12707.0 9802.5 True False 12126.571224089497 11053.347256191732 9099.00096753271 9968.601354187138 10171.353507379488 12512.94103232032 11515.885646131552 12171.418721053054 11275.803849357902 11496.849063989785 1.0547734563265787 0.9614240558148075 0.7914343240386125 0.8670724733971332 0.8847079274301348 1.0883800389719926 1.0016558086512062 1.0586743074827472 0.9807734090095837 1.0 13.488950896141946 -6.749780651749255 24.94857738556977 1.0280488030798784 0.9054537347608005 0.3988795193787512 0.06973455338594621 225.8335834691443 483261.70123776776 0.024579123596890462 0.024380328346508984 1.7791777889380611e-07 6.749780651749255 -0.12259506831907796 HQPST(ph)PDPFLKPR ddPTM_PC-9_AZD4547_30min_R2 1 HQPSTPDPFLKPR 13 1 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 HQPS(0.129)T(0.871)PDPFLKPR 67.846 0.021327000000000002 4236800.0 10201.0 9397.5 13820.0 23607.0 18449.0 14759.0 12656.0 20515.0 11565.0 15115.0 True False 13444.705806018816 12435.058096871408 13636.737770172409 18164.770874514234 15887.674802920612 13836.117396853335 13782.359482079297 17344.87813780172 12176.302289584557 14585.828450647936 0.9217649756069612 0.8525438331423001 0.9349306291591983 1.2453712132962398 1.0892541933204243 0.9486000362385109 0.9449144098131124 1.1891596145182428 0.8348036130264276 1.0 13.832279710776834 -5.537627458767384 24.967466997953416 1.042636135042413 0.8888000311662507 0.2269203966770047 0.11425830625682515 300.5591092624822 508801.8807184379 0.030825851037044136 0.05341821575610374 2.899830018174637e-06 5.537627458767384 -0.1538361038761622 HQPST(ph)PDPFLKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HQPSTPDPFLKPR 13 1 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 HQPS(0.24)T(0.76)PDPFLKPR 65.695 0.024425 4812100.0 8557.6 10956.0 9928.2 11547.0 13062.0 12822.0 12819.0 12560.0 11603.0 10015.0 True False 10006.23265969564 12043.639274318459 10164.925940908175 10900.059025879105 10502.594866351565 12149.591748159028 11604.691518477008 12230.31330842003 11772.671924280612 11830.640221303627 0.84578961683555 1.0180040174521816 0.8592033694511331 0.9213414339361948 0.8877452673642606 1.026959785851746 0.9809013968306001 1.0337828790023305 0.9951001555335416 1.0 13.530240527538869 -6.762846044199089 24.99976643953154 1.007807316654079 0.9108222131333351 0.5469712792903066 0.04583971275014239 29.2922406596166 520584.7803108755 0.014829216053456969 0.01378655501592517 1.726449803646622e-07 6.762846044199089 -0.09698510352074396 HQPST(ph)PDPFLKPR ddPTM_PC-9_Lapatinib_30min_R1 2 HQPSTPDPFLKPR 13 1 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 HQPS(0.236)T(0.764)PDPFLKPR;HQPS(0.224)T(0.776)PDPFLKPR 78.902 0.010435999999999999 12176700.0 65244.0 66773.0 61952.0 55526.0 63026.0 72427.0 60731.0 60477.0 86413.0 52979.0 True False 64313.60859571575 66618.39122102088 56858.54570163569 59609.56726930605 59318.93459388351 69329.46604558319 63875.354020934814 63286.98220214302 76680.25797076932 62136.349559919894 1.0350400216816127 1.0721323620207013 0.9150609281738595 0.9593348771128372 0.954657539652865 1.1157634224831114 1.0279869106140191 1.0185178667619272 1.2340644166233858 1.0 15.923149866801008 -6.758830306431713 24.97966727543743 1.0772189160373133 0.9864002942889138 0.27966587504973905 0.07379960941859944 97.18307941676305 930448.6037583794 0.025185086300947446 0.024097667864442042 1.7424875893314415e-07 6.758830306431713 -0.0908186217483995 HQPTAIIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HQPTAIIAK 9 0 P29401;P29401-2;A0A0B4J1R6;E9PFF2 P29401 TKT Transketolase 0 79.48899999999999 0.016845 8596100.0 82258.0 77991.0 92225.0 86995.0 95944.0 69262.0 89876.0 80430.0 74183.0 69040.0 False True 96182.6547304437 85733.43105543744 94423.9937652604 82120.95219159548 77144.46193976671 65629.77879121754 81362.29463410862 78318.79772262924 75267.78603455209 81556.4054796609 1.1793390619015252 1.0512164011055911 1.1577753238377886 1.0069221627487663 0.9459031634125358 0.8047164217847333 0.9976199190681511 0.9603022259503691 0.9228923907555353 1.0 16.31551057090512 -5.969968739738456 3.154736199716273 0.9339064300571409 1.1216090208844725 0.6648145668566658 0.06023457278571941 0.1504997223081079 3.0936894220407365 0.01800553559613516 0.02710433880438729 1.0715964353432518e-06 5.969968739738456 0.18770259082733154 HQPWQS(ph)PERPLSR ddPTM_PC-9_Lapatinib_30min_R1 2 HQPWQSPERPLSR 13 1 E7ES68;G5E9D5;Q9BQ52-2;Q9BQ52;J3QRS2;V9GYU5;J3QL08;V9GYS7 E7ES68 ELAC2 Zinc phosphodiesterase ELAC protein 2 1 HQPWQS(0.882)PERPLS(0.118)R;HQPWQS(0.919)PERPLS(0.081)R 58.461000000000006 0.030812 192268000.0 44489.0 73448.0 59596.0 61600.0 94110.0 90296.0 72444.0 61425.0 86055.0 54599.0 True False 43854.578701716615 73277.93566863178 54696.246927212705 66130.26949157611 88574.63482737877 86434.25057025669 76194.79584878571 64279.029742987164 76362.57970067646 64036.36440140554 0.6848386711465781 1.1443175507169079 0.8541435391983648 1.0326986878431315 1.3831927476731432 1.349768235255397 1.1898676097719456 1.0037894927960074 1.192487743713951 1.0 15.966603782204501 -4.76058066283068 24.948329538080547 1.1332580618456969 0.6848381426262972 0.42484673874831724 0.1545043841506273 22.147913061631517 643084.1414396014 0.04219554911577309 0.24759431254149694 1.7354788971787506e-05 4.76058066283068 -0.4484199192193997 HQPWQSPERPLS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 HQPWQSPERPLSR 13 1 E7ES68;G5E9D5;Q9BQ52-2;Q9BQ52;J3QRS2;V9GYU5;J3QL08;V9GYS7 E7ES68 ELAC2 Zinc phosphodiesterase ELAC protein 2 1 HQPWQS(0.049)PERPLS(0.951)R 60.08 0.027766000000000002 106130000.0 28200.0 29214.0 40440.0 47377.0 30768.0 30633.0 31868.0 42807.0 42662.0 33905.0 True False 37167.0134035615 38656.85418909297 39903.73917697339 36454.964617353384 26496.394294339058 28717.51366744414 34704.19026350373 36192.16175700114 44917.0262238008 32717.996269878815 1.1359807335689007 1.181516553465765 1.2196266191799157 1.114217518598929 0.8098415953036967 0.8777283740288936 1.0607064680013265 1.1061851544472712 1.372853821893512 1.0 14.997796776361316 -6.005191642252509 24.688112341458087 1.0295738831267132 1.1772277385016132 0.1670638282424104 0.1415665804615603 371.5306907871815 1766782.802251271 0.04399470595604299 0.0631884557658144 9.881169695008522e-07 6.005191642252509 0.14765385537490006 HQPWQSPERPLS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 HQPWQSPERPLSR 13 1 E7ES68;G5E9D5;Q9BQ52-2;Q9BQ52;J3QRS2;V9GYU5;J3QL08;V9GYS7 E7ES68 ELAC2 Zinc phosphodiesterase ELAC protein 2 1 HQPWQS(0.374)PERPLS(0.626)R 68.97800000000001 0.014899 107630000.0 83262.0 104820.0 134220.0 100520.0 94251.0 108650.0 112820.0 136480.0 111560.0 96526.0 True False 82074.66861161911 104577.29573012171 123184.94970418281 107912.57612488995 88707.34148459558 104003.29277552031 118661.26756750049 142821.35904473581 98994.93802111968 113210.39048718994 0.7249746976264169 0.9237429115833224 1.0881063935392177 0.953203815131267 0.7835618365315422 0.918672679494808 1.0481482049205308 1.2615569863341867 0.8744333236119456 1.0 16.788646849712727 -7.270922026769 5.147027677169911 1.0693768930958205 0.9050775148306272 0.2345454412767094 0.12781364744576665 0.259740032256408 22.33602503366087 0.05373391160241205 0.03780957116651283 5.358928630810003e-08 7.270922026769 -0.16429937826519336 HQQIPLHS(ph)PPSK ddPTM_PC-9_AZD4547_30min_R2 1 HQQIPLHSPPSK 12 0 Q8NDX5-2;Q8NDX5;Q8NDX5-7;E7EX82;C9JAU4 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 1 HQQIPLHS(0.995)PPS(0.005)K 66.059 0.034651 6567800.0 21116.0 17715.0 24943.0 32943.0 28951.0 28631.0 24682.0 28333.0 23884.0 29596.0 True False 27830.44875991503 23441.027314293908 24612.239522533335 25348.500314276378 24931.653380636046 26840.69904392627 26878.65018463031 23954.7858775694 25146.45947984761 28559.85304832131 0.9744605027493601 0.820768484859964 0.8617775266872387 0.8875570988193972 0.872961542850147 0.9398052223347806 0.9411340506253124 0.8387573226318619 0.8804828035109818 1.0 14.801700935702053 -6.7315260885082155 24.979996176814225 0.9112768707208047 0.8790376861881736 0.09043639382687774 0.05356556791689463 579.0386985856496 483542.3179981157 0.01754206494725715 0.01753986680840044 1.855555341001939e-07 6.7315260885082155 -0.03223918453263108 HQQIPLHS(ph)PPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HQQIPLHSPPSK 12 0 Q8NDX5-2;Q8NDX5;Q8NDX5-7;E7EX82;C9JAU4 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 1 HQQIPLHS(0.959)PPS(0.041)K 72.523 0.021424000000000002 4975500.0 21757.0 20535.0 20486.0 26811.0 24851.0 26898.0 26413.0 28858.0 26426.0 23707.0 True False 25440.0303796623 22573.579088912888 20974.46393358764 25308.866592434777 19981.624944396168 25487.421528777235 23910.9694264399 28100.508077578426 26812.430256919728 28004.89143549127 0.9084138190024026 0.8060584395019239 0.7489571592127724 0.9037302162278781 0.7135048172003615 0.9101060644168902 0.8538140375054964 1.003414283619253 0.9574195393216091 1.0 14.773391215055504 -7.569626482264802 1.5685860898215847 0.9918816186089248 0.8206560972963608 0.5303542766632622 0.06463165024965635 0.2986788777707091 1.416910289059657 0.04268942148383663 0.019660704699409712 2.6938506713230142e-08 7.569626482264802 -0.17122552131256397 HQQIPLHS(ph)PPSK ddPTM_PC-9_Lapatinib_30min_R1 1 HQQIPLHSPPSK 12 0 Q8NDX5-2;Q8NDX5;Q8NDX5-7;E7EX82;C9JAU4 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 1 HQQIPLHS(0.964)PPS(0.036)K 64.476 0.037889 6258900.0 36507.0 31343.0 38443.0 29169.0 36355.0 36087.0 29368.0 30678.0 37639.0 31671.0 True False 35986.40348543613 31270.427209208163 35282.36493427137 31314.18556493154 34216.67037668003 34543.64313290571 30888.53134127238 32103.41187554514 33399.69946375873 37145.290151045185 0.9688012488017557 0.8418409731638153 0.9498476062725977 0.8430190055750697 0.9211577090270016 0.9299602450927074 0.8315598347911477 0.8642660144799494 0.8991637789863632 1.0 15.18089167492997 HQQQLLAS(ph)PGSSTVDNK ddPTM_PC-9_AZD4547_30min_R2 4 HQQQLLASPGSSTVDNK 17 0 F2Z2X4;Q9C0E2 F2Z2X4 XPO4 Exportin-4 1 HQQQLLAS(0.983)PGS(0.017)STVDNK;HQQQLLAS(0.975)PGS(0.01)S(0.006)T(0.008)VDNK;HQQQLLAS(0.987)PGS(0.012)S(0.001)TVDNK;HQQQLLAS(1)PGSSTVDNK 251.74 3.5203999999999995e-48 114984000.0 341426.0 330421.0 410250.0 502924.0 424513.0 411889.0 421094.0 460259.0 386138.0 435797.0 True False 449992.36589802685 437223.12651517324 404809.8169474121 386982.641898344 365576.6975777672 386133.5157173612 458570.55023282993 389136.54724964657 406548.4663636487 420539.87967628293 1.0700349423327353 1.03967102204845 0.9625955504125333 0.9202043863146341 0.8693032819127059 0.918185252762695 1.0904329705563756 0.9253261487333625 0.966729877500787 1.0 18.681883091761804 -5.204515961118842 3.1526476174159788 0.9521807793731936 1.0642089143822306 0.3339930770030004 0.05609126286772093 0.30337498207800334 5.914889075886848 0.015813817297094346 0.05044992777719829 6.244304008961547e-06 5.204515961118842 0.11202813500903708 HQQQLLAS(ph)PGSSTVDNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HQQQLLASPGSSTVDNK 17 0 F2Z2X4;Q9C0E2 F2Z2X4 XPO4 Exportin-4 1 HQQQLLAS(1)PGSSTVDNK;HQQQLLAS(0.999)PGSSTVDNK 132.01 1.4109000000000002e-05 42230400.0 110481.0 156583.0 123024.0 151772.0 159350.0 169038.0 176800.0 138685.0 160156.0 117846.0 True False 129183.25120078471 172127.5254190037 125957.35873111802 143268.7068914632 128126.51140354646 160173.34970560798 160052.22407884686 135044.665698904 162497.9785146155 139210.54693157715 0.9279702870808997 1.2364546308664779 0.9047975279705412 1.0291512392511515 0.9203793407012577 1.1505834380805513 1.1497133486409872 0.9700749596600556 1.1672820924587293 1.0 17.086908991869628 -6.776371469699025 24.99822867749533 1.0895468425115724 1.0125923347588672 0.13132529363336565 0.10646727879261585 557.471447832718 933272.6169826546 0.036362017306472344 0.03218974457872759 1.6735108419219293e-07 6.776371469699025 -0.07695450775270518 HQQQLLAS(ph)PGSSTVDNK ddPTM_PC-9_Lapatinib_30min_R1 3 HQQQLLASPGSSTVDNK 17 0 F2Z2X4;Q9C0E2 F2Z2X4 XPO4 Exportin-4 1 HQQQLLAS(0.997)PGS(0.002)S(0.001)TVDNK;HQQQLLAS(0.964)PGS(0.027)S(0.008)TVDNK;HQQQLLAS(0.999)PGS(0.001)STVDNK 261.66 1.5083000000000002e-58 78973000.0 213964.0 195878.0 207236.0 169630.0 182318.0 198077.0 196670.0 190586.0 213620.0 149063.0 True False 210912.83412380828 195424.45652570872 190197.8560340941 182105.15606909207 171594.41369097942 189605.70845003935 206852.61028629928 199441.3213283997 189559.86608167435 174828.34093603777 1.206399563106146 1.1178076476582604 1.0879120342603912 1.0416226287688481 0.9815022711549868 1.0845250114191038 1.1831755033468963 1.1407836982298354 1.0842627978207848 1.0 17.415579549513488 -9.69866938599387 0.00869520789715295 2.131603977202273e-06 2.1281481581406636 0.1591619138813325 0.06338647075871746 13716.724351090052 32.720166098340236 4144.8932286826675 3863.395916867918 2.001384877877085e-10 9.69866938599387 2.1281460265366863 HQQQLLASPGS(ph)STVDNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HQQQLLASPGSSTVDNK 17 0 F2Z2X4;Q9C0E2 F2Z2X4 XPO4 Exportin-4 1 HQQQLLAS(0.286)PGS(0.711)S(0.002)T(0.001)VDNK 250.38 2.5276999999999993e-131 0.0 19988.0 22010.0 21235.0 24257.0 23625.0 22829.0 29309.0 24636.0 23131.0 19928.0 True False 23371.573619004903 24195.00734097749 21741.322934185955 22897.95893225508 18995.850843481516 21631.807051842352 26532.639341215585 23989.331103999673 23469.247115447288 23540.788650038794 0.9928118367846774 1.0277908569956775 0.9235596673244898 0.9726929404388218 0.8069334942799468 0.918907491733787 1.127092203054627 1.0190538414251529 0.9969609542120677 1.0 14.522875033079634 -7.2307627911815295 24.993703085675044 1.0373645984155344 0.9390484379951949 0.3447407114321356 0.06435253902567352 821.9527414941848 669685.7070595857 0.026340455271665043 0.0204004455422113 5.878103230372044e-08 7.2307627911815295 -0.09831616042033953 HQQVPHILQGLLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 HQQVPHILQGLLSPR 15 0 H0Y4E8;Q9Y2K2-7;Q9Y2K2;Q9Y2K2-8;Q9Y2K2-6 H0Y4E8 SIK3 Serine/threonine-protein kinase SIK3 1 HQQVPHILQGLLS(1)PR 90.44200000000001 0.007582899999999999 0.0 6744.0 7175.6 7271.6 14316.0 10042.0 8187.6 8469.4 11059.0 9588.0 10075.0 True False 8888.451716085769 9494.972373494058 7175.173832820968 11015.667379995157 8647.841637537467 7675.628077679817 9223.160192598169 9350.085660538598 10094.802105710049 9722.277316591337 0.9142355671049804 0.9766201954855396 0.7380136977348233 1.1330336526398619 0.8894872421278999 0.7894886997906493 0.9486625295967015 0.961717646603478 1.038316618317705 1.0 13.247078570564458 -7.904505684969363 2.4880229669414873 1.0159970986716083 0.9104513785954285 0.1535982547086624 0.10039081334271259 0.5779854056912267 6.935460941742297 0.07245092187792816 0.027703876437485276 1.24593192775844e-08 7.904505684969363 -0.1055457200761798 HQRT(ph)HLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HQRTHLR 7 1 Q9UEG4 Q9UEG4 ZNF629 Zinc finger protein 629 1 HQRT(1)HLR;HQRT(1)HLR;HQRT(1)HLR 70.91199999999999 0.030826 5739900.0 4819.74 14149.3 16242.0 11002.9 30039.9 21669.7 9220.5 15694.1 22300.4 27331.6 True False 5635.626787795816 15553.948994533965 16629.270878128013 10386.443184883095 24153.797238226478 20533.30278467336 8347.067489360892 15282.146504273462 22626.501161788103 32286.602723173437 0.17455000874870283 0.4817462254512844 0.5150517389738405 0.32169514005350314 0.7481058767725443 0.6359697537931346 0.2585303743762999 0.4733277959066542 0.7008015478057134 1.0 14.978648024518648 -14.522878745268722 0.15146740918373047 2.87348564252502 0.32378793495391067 0.5257548594747037 0.1626826549788173 119.06303624663322 1.0621847959754915 66.95703953346509 0.8395550401727805 3.000000000080239e-15 14.522878745268722 -2.5496977075711094 HQRT(ph)HLR ddPTM_PC-9_Lapatinib_30min_R1 1 HQRTHLR 7 1 Q9UEG4 Q9UEG4 ZNF629 Zinc finger protein 629 1 HQRT(1)HLR 65.803 0.040287 3184300.0 2635.0 3052.0 2011.5 3065.7 4568.8 2366.0 6096.7 5964.4 4564.5 5097.6 True False 2597.424416800182 3044.9332815143216 1846.1222346145432 3291.1618048754012 4300.072166606404 2264.811695415384 6412.357294617791 6241.5277981127 4050.397943684124 5978.71336787496 0.43444538263980964 0.5092957454484217 0.3087825291197592 0.5504799448255191 0.7192303597813717 0.37881255649162787 1.0725313123510658 1.0439583592767474 0.6774698324639328 1.0 12.54561933137594 -7.260784992578607 24.999960803989705 0.9521530829056132 0.49049672688479296 0.7161167966891553 0.14337539046099876 33.32486381999886 1273163.927796467 0.058051441424476574 0.04223266151442659 5.485484691804223e-08 7.260784992578607 -0.4616563560208202 HQS(ph)DGNEIAHTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HQSDGNEIAHTR 12 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 HQS(1)DGNEIAHTR 105.5 0.0010107 6092700.0 28028.0 24617.0 28731.0 33059.0 41069.0 35146.0 37231.0 31041.0 27769.0 30972.0 True False 32772.586821766556 27060.813071914698 29416.056002924255 31206.811408724083 33021.82426628328 33302.881889003045 33704.21015090237 30226.20664065813 28175.069091213332 36586.97842578289 0.8957445580876849 0.7396296233319151 0.8040034260439153 0.8529485831148222 0.9025567479771098 0.9102386510697605 0.9212078067411813 0.8261465674726964 0.7700846121624061 1.0 15.159042653653923 -5.917916233386192 3.7077053256662365 0.8822287471835438 0.8060622337176938 0.19689063943882412 0.06695090618669343 0.37911645313041764 10.240394221858997 0.019624463550139058 0.030104785598483896 1.2080468204132368e-06 5.917916233386192 -0.07616651346585002 HQS(ph)DGNEIAHTR ddPTM_PC-9_Lapatinib_30min_R1 1 HQSDGNEIAHTR 12 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 HQS(1)DGNEIAHTR 100.69 0.0016748000000000002 8884800.0 54350.0 86464.0 90152.0 78034.0 101370.0 83733.0 80591.0 91641.0 104980.0 86598.0 True False 53574.95903343068 86263.79792033248 82740.05055678365 83772.88067379309 95407.61590108812 80151.9347811565 84763.60764520858 95898.97541191832 93156.04691159142 101566.34891541842 0.5274872987513451 0.8493344384385672 0.8146403945827296 0.8248094134363023 0.939362465224982 0.7891583741767143 0.8345638939507151 0.9442002832235338 0.9171940106773863 1.0 16.63206296026253 -4.417149952007739 1.7254382560289794 0.8784624851294832 3.1706363475787157e-16 0.7246088284055421 0.06498833153281894 1.588833775726726 2.068019061901203 0.01766672245164292 3.138079683795875 3.826925854561417e-05 4.417149952007739 -0.8784624851294829 HQS(ph)FGAAVLSR ddPTM_PC-9_AZD4547_30min_R2 4 HQSFGAAVLSR 11 0 Q5VV41 Q5VV41 ARHGEF16 Rho guanine nucleotide exchange factor 16 1 HQS(1)FGAAVLSR;HQS(1)FGAAVLSR;HQS(1)FGAAVLSR;HQS(1)FGAAVLSR 126.07 0.00024337 215280000.0 83985.6 84722.5 101362.0 152690.0 112214.0 113815.0 92872.0 117693.0 89941.0 107361.0 True False 110691.2737909986 112107.39128621301 100017.87365124577 117489.67953698398 96635.02305463348 106698.13005778576 101137.42808309635 99506.25116608801 94695.09764180936 103602.32406814516 1.0684246206503112 1.0820934018089554 0.9654018338957175 1.1340448256711337 0.9327495683501377 1.0298816268600723 0.9762081014376908 0.960463503701298 0.9140248396312326 1.0 16.66069684120626 -6.560008181336886 0.7719621704837062 0.9552552242870139 1.0635705057001272 0.3489684610755591 0.054199584923787056 0.7384748054825272 0.978847113515422 0.03317765450810453 0.04029895388588192 2.754176819048636e-07 6.560008181336886 0.1083152814131133 HQS(ph)FGAAVLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 HQSFGAAVLSR 11 0 Q5VV41 Q5VV41 ARHGEF16 Rho guanine nucleotide exchange factor 16 1 HQS(1)FGAAVLSR;HQS(1)FGAAVLSR;HQS(1)FGAAVLSR;HQS(1)FGAAVLSR;HQS(1)FGAAVLSR;HQS(1)FGAAVLSR 132.15 6.949899999999999e-05 194257300.0 138413.0 124654.0 156478.0 160755.0 168691.0 142010.0 147803.0 121712.0 129192.0 112792.0 True False 161843.58711863746 137028.8253104139 160209.02896612 151748.4185247418 135637.20950847593 134562.74560568258 133802.0298389466 118517.18896452356 131081.1885927488 133240.29673901922 1.2146744722104916 1.028433804668083 1.2024067259466185 1.1389078397354133 1.0179893983135717 1.009925292115295 1.0042159400247184 0.8894995873257913 0.9837953817342548 1.0 17.02367094658659 -6.463961282046138 1.7884475720558084 0.9672219916199719 1.1442442471462775 0.662616216740299 0.05693347255795956 0.2165596208090203 1.3881110009214481 0.02106305241885508 0.023975550615591572 3.435885779315405e-07 6.463961282046138 0.17702225552630557 HQS(ph)FGAAVLSR ddPTM_PC-9_Lapatinib_30min_R1 3 HQSFGAAVLSR 11 0 Q5VV41 Q5VV41 ARHGEF16 Rho guanine nucleotide exchange factor 16 1 HQS(1)FGAAVLSR;HQS(1)FGAAVLSR;HQS(1)FGAAVLSR 136.57 4.1543e-05 178749000.0 109449.0 98971.0 110852.0 93921.0 101804.0 106772.0 94377.0 90415.0 109113.0 77771.0 True False 107888.23718951178 98741.83873026034 101738.17646109452 100828.26365127115 95816.08887436475 102205.61045768867 99263.37926979235 94616.01097618543 96823.54492917203 91213.61372665629 1.182808495153202 1.0825340066688314 1.115383683470514 1.1054080584223698 1.050458204205141 1.1205082912729734 1.0882517994217304 1.0373014192785437 1.061503222746193 1.0 16.476961543744103 -1.5228787453770973 0.07076357037619048 0.9030910315929325 1.5144601826269068 0.6493709719153992 0.02865956218666796 160.15224073787633 0.8393295375866545 1.2538196407545934 9.738956146450926 0.02999999999331607 1.5228787453770973 0.6113691510339744 HQTLEVSLS(ph)RDSPLK ddPTM_PC-9_Lapatinib_30min_R1 1 HQTLEVSLSRDSPLK 15 1 Q8NCF5;H3BSZ7;Q8NCF5-3;Q8NCF5-2 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 HQTLEVS(0.011)LS(0.664)RDS(0.325)PLK 60.901 0.020689 9494800.0 27321.0 28282.0 63433.0 33137.0 55196.0 63390.0 41141.0 46209.0 73319.0 25969.0 True False 26931.39752994222 28216.514766640885 58217.783598461014 35574.005521791485 51949.47979951122 60678.9574693073 43271.07967554099 48356.03883424818 65061.04213670203 30457.7070484826 0.8842227514721578 0.9264162506299577 1.9114302828440073 1.1679804216766796 1.7056267471749595 1.9922365584749533 1.4206939349262915 1.587645411300168 2.136110969651715 1.0 14.894519714864495 -5.244976400793611 23.460141350953137 1.6299769809801992 0.9053190245000277 0.4160799119936369 0.3360261672868417 328.64823493139926 468326.60665869154 0.0814982190180325 0.2139275662530143 5.688838426859751e-06 5.244976400793611 -0.7246579564801715 HQTLEVSLSRDS(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 1 HQTLEVSLSRDSPLK 15 1 Q8NCF5;H3BSZ7;Q8NCF5-3;Q8NCF5-2 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 HQTLEVSLS(0.02)RDS(0.98)PLK 86.959 0.002507 11888000.0 11735.0 17021.0 36975.0 71868.0 55235.0 56042.0 30269.0 49006.0 35629.0 53638.0 True False 15466.485896836666 22522.705386203583 36484.6873409642 55299.94294953143 47566.57367550107 52537.68488071379 32962.88236117717 41433.24874584991 37512.27620195489 51760.14994613657 0.29881068569027786 0.435136015054854 0.7048798618035583 1.0683883838643917 0.9189806004233088 1.0150218833482196 0.6368390044364151 0.8004854852423496 0.7247327575555998 1.0 15.659554176289342 -5.299397753192304 2.7014887078709315 0.8699454827184696 0.33194715416588694 0.7107116395359399 0.12979322064046445 0.15706606915091542 2.2233856160757774 0.03744730880560058 0.1105002295103279 5.018827243696891e-06 5.299397753192304 -0.5379983285525827 down HQTLEVSLSRDS(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 1 HQTLEVSLSRDSPLK 15 1 Q8NCF5;H3BSZ7;Q8NCF5-3;Q8NCF5-2 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 HQTLEVS(0.001)LS(0.1)RDS(0.899)PLK 72.815 0.0079522 9110800.0 35637.0 28543.0 79144.0 43593.0 76425.0 78015.0 45932.0 56814.0 94220.0 41759.0 True False 35128.80984497461 28476.91043717668 72637.08582467477 46798.97464198498 71929.83175733112 74678.48031184754 48310.13421299791 59453.785849704036 83607.95141941459 48976.9875096301 0.7172513384590551 0.581434503940803 1.4830860270936939 0.9555298727342743 1.4686454887244325 1.5247667141055559 0.9863843545603725 1.2139126735390562 1.707086443464396 1.0 15.579816418486551 -5.254674742818046 24.994156902631634 1.2916954964627625 0.649342845215074 0.5238664793090334 0.24523362514372582 397.24162629859217 1467729.157584568 0.06119447774813667 0.1543885815975053 5.563207478879936e-06 5.254674742818046 -0.6423526512476885 HQYSDYDYHS(ph)SSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HQYSDYDYHSSSEK 14 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 HQYSDYDY(0.003)HS(0.391)S(0.391)S(0.215)EK 74.475 0.031266 0.0 19215.0 20918.0 22374.0 28582.0 32071.0 25892.0 24839.0 24946.0 23544.0 15225.0 True False 22467.719986450826 22994.600797754065 22907.4810138675 26980.643204094264 25786.91777359983 24534.177939739 22486.07010121307 24291.193932471833 23888.28645912805 17985.171978966322 1.2492357600320336 1.2785310490578725 1.2736870706967842 1.5001604230222627 1.4337876670713885 1.3641336301054972 1.2502560513466623 1.3506233891385866 1.3282211861563196 1.0 14.134520334519856 -10.228082280997075 0.7313408630159819 0.9612856641967759 1.3428479553782513 0.6311594811037455 0.07719408882073162 17.402818903147736 5.822271711544653 1.8083199013576376 0.030054567382453046 5.914495681177176e-11 10.228082280997075 0.38156229118147544 HRAEAPPLEREDS(ph)GTFSLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HRAEAPPLEREDSGTFSLGK 20 2 G5E9Q4;O75569 G5E9Q4 PRKRA Interferon-inducible double-stranded RNA-dependent protein kinase activator A 1 HRAEAPPLEREDS(0.894)GT(0.053)FS(0.053)LGK 44.831 0.027686000000000002 7140400.0 15762.0 9131.5 12647.0 23089.0 18303.0 25461.0 15795.0 20253.0 14304.0 14901.0 True False 18430.19528630956 10038.01497201889 12948.552444014591 21795.39818554797 14716.658539184857 24125.78033847113 14298.783254102831 19721.380209827304 14513.168939490643 17602.43334374891 1.0470254269052301 0.5702629162679745 0.7356115027478837 1.2382037051308075 0.8360581887623583 1.3705934780340374 0.8123185570352242 1.1203780650492217 0.8244978779962062 1.0 14.103487258997193 -5.733225700635966 24.99791373096032 1.0310624550313645 0.7628960144160069 0.23065374222901713 0.20353305169524785 276.49685658136593 244980.00044428025 0.05146896906015356 0.08912467195135729 1.8483078131559252e-06 5.733225700635966 -0.26816644061535766 HRDHQVAALSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HRDHQVAALSER 12 1 C9J453;A0A087X255;O15344-2;O15344 C9J453 MID1 E3 ubiquitin-protein ligase Midline-1 0 61.233000000000004 0.025536 548090.0 2034.0 1008.3 2166.3 2202.0 2289.7 1860.3 1094.4 2272.3 2330.1 2032.5 False True 2378.3160266688005 1108.3973603774457 2217.9528077385 2078.6290789803224 1841.0497217489801 1762.742593129016 990.7305092301453 2212.6545327008616 2364.1733043838894 2400.976160738853 0.9905621161756644 0.4616444671555415 0.9237712743703246 0.8657433226411816 0.7667921705571759 0.7341774657964811 0.4126365456811814 0.9215645573173707 0.9846717110495431 1.0 11.229405363801188 -7.9795218015536635 24.999442174419624 0.9792635509087926 0.7340111163355416 0.28050329190772305 0.17267883113768903 287.81358803273474 351357.83648441965 0.0930791612758853 0.04470696437282396 1.0482821685660552e-08 7.9795218015536635 -0.24525243457325097 HRDLLHNEDRHDDYFQER ddPTM_PC-9_AZD4547_30min_R2 2 HRDLLHNEDRHDDYFQER 18 2 Q8N684-2;Q8N684;Q8N684-3 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 0 ; 59.606 0.007259999999999999 14912900.0 36001.0 14898.9 71684.0 178211.0 114896.0 41980.0 37888.0 39839.0 34491.0 68260.0 False True 47448.56913268145 19714.67806113087 70733.42332250644 137127.20728250348 98944.67364932316 39354.98396367659 41259.958601218415 33682.79795914611 36314.123845227936 65870.238176727 0.720333954241656 0.29929568507460447 1.0738297792810727 2.0817779178905824 1.5021150126079532 0.5974622994088601 0.6263824109838457 0.5113507843827226 0.5512978979641566 1.0 16.007339146247993 -6.789111076908945 24.646239684613107 0.6248254770209537 1.1381645015026136 0.21521382233294517 0.4544313644270553 325.3423105827046 289768.7393636129 0.18338695446261163 0.1617706239073657 1.6251330520053904e-07 6.789111076908945 0.5133390244816599 HRDYETATLSDIK ddPTM_PC-9_AZD4547_30min_R2 2 HRDYETATLSDIK 13 1 O43707;O43707-2 O43707 ACTN4 Alpha-actinin-4 0 ; 157.56 6.837399999999999e-05 19828400.0 51741.0 48025.0 73279.0 84781.0 85615.0 72741.0 61644.0 79402.0 60748.0 75754.0 False True 68193.56172034299 63548.14206993873 72307.27258035193 65236.0503033927 73728.83507247272 68192.493770886 67130.19657974837 67132.24537644311 63959.01526050001 73101.87551772306 0.9328565271052438 0.869309325101131 0.9891301976625964 0.8923991325992267 1.0085765180484003 0.9328419180483705 0.9183101815694605 0.9183382081649512 0.8749298811764901 1.0 16.15762080030182 -6.190439725809426 0.004253563655196104 1.8578182060552961 4.615506231113502e-08 0.06164039381703723 0.04630985577769287 85479.00245131017 99.9424693594041 21451.1343847081 22200.523975801978 6.450008310338257e-07 6.190439725809426 -1.857818159900234 HRDYETATLSDIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HRDYETATLSDIK 13 1 O43707;O43707-2 O43707 ACTN4 Alpha-actinin-4 0 ; 114.76 0.00013506 18876900.0 62740.0 56066.0 66960.0 91878.0 95161.0 73819.0 77488.0 83001.0 76859.0 67652.0 False True 73360.64282851544 61631.861952714404 68556.58034721416 86730.3735324948 76514.8851689543 69947.80168907745 70147.77567546174 80822.31169682903 77982.91747205771 79916.77206706253 0.9179630374329248 0.7712005922986447 0.8578497175747362 1.0852587171528225 0.9574321283240328 0.8752580951390332 0.8777603732117323 1.0113310336033918 0.9758016428218346 1.0 16.286210691697683 -5.550924726084521 24.9657209324555 0.962054507329149 0.8370675839548323 0.40034105913239826 0.06691734983930664 200.4046231178672 178393.49689891978 0.018843965506183846 0.0326395037299582 2.8123882442126253e-06 5.550924726084521 -0.12498692337431672 HRDYETATLSDIK ddPTM_PC-9_Lapatinib_30min_R1 2 HRDYETATLSDIK 13 1 O43707;O43707-2 O43707 ACTN4 Alpha-actinin-4 0 ; 120.9 0.00026645 20468700.0 85350.0 69857.0 71631.0 65082.0 71025.0 74288.0 64253.0 62366.0 76878.0 66224.0 False True 84132.89334872684 69695.25040850118 65741.77568365622 69868.34738718758 66847.44914052254 71110.87541378618 67579.70594765653 65263.75203827659 68219.19007877048 77670.73016206657 1.0831994648843446 0.8973167918349181 0.8464163468848616 0.8995453916990525 0.8606517410231586 0.9155427696560507 0.8700794470020526 0.8402618580010544 0.8783127174989259 1.0 16.24508340796828 -4.763851473564996 4.963259552689056 0.8821259996367948 1.0959354160361026 0.6375258462941115 0.043552867767463525 0.09731006910215038 6.2343514232899695 0.00997943625245746 0.07270968232634073 1.7224575457144294e-05 4.763851473564996 0.21380941639930773 HRGS(ph)EEDPLLSPVETWK ddPTM_PC-9_AZD4547_30min_R2 2 HRGSEEDPLLSPVETWK 17 1 A0A0A0MSK6;Q13017-2;Q13017;H0YK04 A0A0A0MSK6 ARHGAP5 Rho GTPase-activating protein 5 1 HRGS(1)EEDPLLSPVETWK;HRGS(1)EEDPLLSPVETWK 95.429 0.00077904 5906700.0 52954.0 50400.0 75911.0 96700.0 75530.0 76075.0 65056.0 80463.0 76207.0 74527.0 True False 69792.27048837571 66690.81437428237 74904.37054063367 74407.30900010696 65043.96324270106 71318.01822383759 70845.85796982849 68029.29220579778 80235.14644032605 71917.83241425322 0.9704445774500811 0.9273195831339472 1.0415270875959903 1.0346155675481727 0.9044205179605795 0.9916597293010633 0.9850944555969087 0.9459307924346622 1.1156502323118465 1.0 16.134061918584052 -8.249249083571936 24.99956395431062 1.0578251234045701 0.9762557953223999 0.3205024893143823 0.04814305358117672 783.691561866758 1607184.3920150371 0.03268556004079151 0.012132821479427996 5.633144819567461e-09 8.249249083571936 -0.08156932808217021 HRGS(ph)EEDPLLSPVETWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HRGSEEDPLLSPVETWK 17 1 A0A0A0MSK6;Q13017-2;Q13017;H0YK04 A0A0A0MSK6 ARHGAP5 Rho GTPase-activating protein 5 1 HRGS(1)EEDPLLSPVETWK;HRGS(1)EEDPLLSPVETWK 123.58 9.8404e-05 2584100.0 20730.4 22037.0 25050.0 29249.0 31765.0 28329.0 36239.0 31498.0 26050.0 22940.0 True False 24239.64727593654 24224.6877225407 25647.287002654033 27610.273356537422 25540.87627696045 26843.3773696457 32806.17957236043 30671.21087488964 26430.931968241828 27098.840407059924 0.8944902037070747 0.8939381670453163 0.9464348517279092 1.0188728721153786 0.9425080886600009 0.9905729162732856 1.2106119331886098 1.1318274292983777 0.9753528775111687 1.0 14.725943497741985 -7.024935585827189 13.524345130903471 1.0918958745806813 0.9440450813414577 0.47134182498799315 0.06949016015519287 2.194960035232228 1189.310089655491 0.027009424400333354 0.021298848355320196 9.442009089432469e-08 7.024935585827189 -0.14785079323922357 HRGS(ph)EEDPLLSPVETWK ddPTM_PC-9_Lapatinib_30min_R1 1 HRGSEEDPLLSPVETWK 17 1 A0A0A0MSK6;Q13017-2;Q13017;H0YK04 A0A0A0MSK6 ARHGAP5 Rho GTPase-activating protein 5 1 HRGS(1)EEDPLLSPVETWK 119.37 4.7175e-05 1954200.0 33337.0 27680.0 35513.0 29627.0 30412.0 31405.0 29693.0 27603.0 34149.0 23773.0 True False 32861.608266742944 27615.908660654135 32593.258224144287 31805.86841277474 28623.225952292483 30061.881358630628 31230.358251035163 28885.53614970572 30302.780015088007 27882.131374468663 1.1785902528539811 0.990451852111338 1.1689658077570622 1.1407258643755978 1.0265795526127688 1.0781773084305146 1.1200850405443692 1.035987377068163 1.0868172023188982 1.0 14.76705322790952 -7.9000053014548905 0.011698379509698365 4.7378722033981086e-07 2.136973114775118 0.22918271250628386 0.056979209822267556 1164.910243482482 13.922312924727681 1268.7814614068927 1271.6303936609695 1.2589100441212547e-08 7.9000053014548905 2.136972640987898 HRGSEEDPLLS(ph)PVETWK ddPTM_PC-9_AZD4547_30min_R2 1 HRGSEEDPLLSPVETWK 17 1 A0A0A0MSK6;Q13017-2;Q13017;H0YK04 A0A0A0MSK6 ARHGAP5 Rho GTPase-activating protein 5 1 HRGS(0.001)EEDPLLS(0.976)PVET(0.023)WK 53.981 0.024316 1341800.0 7171.4 5447.0 9858.8 17998.0 13893.0 12428.0 8383.2 13402.0 8188.7 12168.0 True False 9451.756025613506 7207.63622810945 9728.06587037451 13848.83916632809 11964.196760636129 11650.875195344754 9129.288559589693 11331.028847322383 8621.537964437617 11742.002023650957 0.8049526823939908 0.6138336727920585 0.8284844314266051 1.1794274211870772 1.0189230709156432 0.9922392426672509 0.7774899494312224 0.9649997355220358 0.734247698737571 1.0 13.519390789986263 -5.524009143668232 24.99994037166621 0.9524440540672982 0.7123346119508581 0.3810326620581628 0.12507713979475768 36.34221170538973 803742.0601935036 0.03488553800546605 0.06106067656316668 2.992201637909794e-06 5.524009143668232 -0.24010944211644003 HRHPLDHDCSGEGHPTSR ddPTM_PC-9_AZD4547_30min_R2 1 HRHPLDHDCSGEGHPTSR 18 1 A0A087X0D9;E7EV05;E9PFU9;B4DEN4;Q8WV99-2;Q8WV99;B8ZZ56 A0A087X0D9 ZFAND2B AN1-type zinc finger protein 2B 0 50.178000000000004 0.014865 642910.0 0.0 0.0 522.3 2093.8 901.18 1557.1 0.0 799.93 915.15 707.67 False True 0.0 0.0 515.3739607352426 1611.1067588875298 776.0667124991052 1459.7342908489954 0.0 676.3191990627219 963.5229606842464 682.8946886979842 0.0 0.0 0.7546902461898791 2.359231643694999 1.1364368845491593 2.1375686690903155 0.0 0.9903711513003576 1.4109393097218426 1.0 9.415519302978927 -5.425306087353575 4.196090027829118 1.282699012646826 0.020975147575927427 0.40777396534619037 0.614922449769848 0.225638508398525 6.845627979457574 0.16862813169315177 0.36778823554352913 3.7557261034920082e-06 5.425306087353575 -1.2617238650708986 HRHS(ph)PTGPPGFPR ddPTM_PC-9_AZD4547_30min_R2 3 HRHSPTGPPGFPR 13 1 P98175-5;P98175-2;P98175 P98175-5 RBM10 RNA-binding protein 10 1 HRHS(1)PTGPPGFPR;HRHS(0.98)PT(0.02)GPPGFPR;HRHS(0.99)PT(0.01)GPPGFPR 92.26899999999999 0.0019812000000000002 54260700.0 105372.0 100096.0 134839.0 209142.0 143559.0 143349.0 116747.0 172510.0 121676.0 141491.0 True False 138878.10412624368 132450.074516035 133050.9467577624 160927.54311168953 123628.31085871739 134385.36436896332 127137.25683109273 145852.54338543414 128107.54495352271 136537.4431565088 1.0171429969363925 0.9700641190725349 0.974464906342578 1.1786330503290816 0.9054535371444298 0.9842381786432122 0.9311530514406887 1.0682237781342347 0.9382594399887573 1.0 17.058937115315366 HRHS(ph)PTGPPGFPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HRHSPTGPPGFPR 13 1 P98175-5;P98175-2;P98175 P98175-5 RBM10 RNA-binding protein 10 1 HRHS(1)PTGPPGFPR;HRHS(0.999)PT(0.001)GPPGFPR;HRHS(0.998)PT(0.002)GPPGFPR;HRHS(0.997)PT(0.003)GPPGFPR 101.35 0.00085318 45711400.0 140040.9 133712.1 165445.0 167750.0 179252.0 157879.0 180497.0 158890.0 157336.8 122161.9 True False 163747.0584361467 146986.15361551632 169389.83625365663 158351.5113528376 144128.85737124877 149599.54730990488 163399.01747488405 154719.3058578706 159637.55304801825 144308.88543693177 1.1346983793850318 1.0185523446493154 1.1738004610096315 1.0973095029691915 0.9987524810746204 1.0366620659355401 1.1322866016195197 1.0721398435683198 1.1062212320791962 1.0 17.13880060712207 -11.02704101938261 3.2010974951522106 0.9978397260282498 1.0835521187815953 0.1920619557579537 0.05252025675460414 5316128.595000237 3826967.2850967585 75247.42072475178 0.012760398982520274 9.396345573078063e-12 11.02704101938261 0.08571239275334552 HRHS(ph)PTGPPGFPR ddPTM_PC-9_Lapatinib_30min_R1 5 HRHSPTGPPGFPR 13 1 P98175-5;P98175-2;P98175 P98175-5 RBM10 RNA-binding protein 10 1 HRHS(0.991)PT(0.009)GPPGFPR;HRHS(0.85)PT(0.15)GPPGFPR;HRHS(0.991)PT(0.009)GPPGFPR;HRHS(0.845)PT(0.155)GPPGFPR;HRHS(0.92)PT(0.08)GPPGFPR 64.64 0.017525 46386800.0 145739.3 138156.0 142436.0 122357.6 134516.0 134634.2 111955.0 127498.0 144693.0 114716.5 True False 143661.0308566859 137836.108270279 130725.46189886038 131356.18607698812 126604.03334863143 128876.20911364893 117751.48209997785 133422.02253433235 128396.15065516207 134545.09417487192 1.0677537649196316 1.0244603054135117 0.9716107651532276 0.976298592546681 0.9409784438820246 0.9578662819630199 0.8751822786413382 0.9916528235575808 0.9542982703500292 1.0 17.03773026237824 -4.9285323463122115 1.0777244865214448 0.9501705591001461 1.1103332033934192 0.563528845790789 0.03222911277584003 0.9885611409676912 1.1188153763740318 0.010330920809825768 0.1714568289782705 1.1788747172242908e-05 4.9285323463122115 0.1601626442932731 HRLDLGEDYPSGK ddPTM_PC-9_AZD4547_30min_R2 1 HRLDLGEDYPSGK 13 1 O43143 O43143 DHX15 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 0 60.628 0.02553 3809500.0 32763.0 29454.0 46642.0 66639.0 58907.0 50204.0 40232.0 51872.0 39262.0 49184.0 False True 43180.95248726539 38974.42949563716 46023.49660465856 51276.408112286736 50728.77985883481 47064.7359436022 43812.57006028874 43856.37429997809 41337.30916503839 47462.08313044449 0.9097989308346862 0.8211698038731272 0.9696897727427571 1.0803657305002603 1.0688275042503328 0.9916281132088067 0.923106765876132 0.9240296971256721 0.8709543795502441 1.0 15.534487801952537 -5.335028613652096 7.015139213831704 0.9816393509649399 0.8659253469967897 0.3337633840572003 0.06387522898423943 0.2913021912847838 23.75669864923026 0.01892049373290029 0.039860762641159196 4.623505582587011e-06 5.335028613652096 -0.11571400396815024 HRPELIDYGK ddPTM_PC-9_AZD4547_30min_R2 1 HRPELIDYGK 10 1 P12814-4;P12814-3;P12814;P12814-2;H9KV75;G3V2N5;G3V2W4;G3V2X9 P12814-4 ACTN1 Alpha-actinin-1 0 65.5 0.021919 8845800.0 94676.0 89281.0 109760.0 151390.0 126140.0 106930.0 110440.0 117650.0 111680.0 110460.0 False True 124780.99861686499 118139.33726488704 108304.51068409003 116489.37445218395 108627.63833489078 100243.65019618746 120268.94604937105 99469.89582804628 117583.17680076121 106592.82902140733 1.1706322063354269 1.1083234993337197 1.0160581314746693 1.0928443828879808 1.0190895516346112 0.9404352161068475 1.1283024116492593 0.9331762440423592 1.1031058832029559 1.0 16.70175085922019 -4.272264554475181 0.8554741482492465 1.0230882012189668 1.4214386997199906 0.3559616196423778 0.061635585123208506 5.234559694945332 1.620525876045261 0.020349422757100118 2.4114600958615022 5.342388237659284e-05 4.272264554475181 0.3983504985010238 HRPELIDYGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HRPELIDYGK 10 1 P12814-4;P12814-3;P12814;P12814-2;H9KV75;G3V2N5;G3V2W4;G3V2X9 P12814-4 ACTN1 Alpha-actinin-1 0 78.655 0.0090556 7182700.0 53484.0 54155.0 61994.0 65977.0 71574.0 65584.0 68313.0 71845.0 55938.0 54483.0 False True 62537.784842848625 59531.150502073375 63472.17207355422 62280.52259032004 57549.58849825808 62144.65958596638 61841.898096709505 69959.14487606968 56755.98742570104 64360.33661280927 0.9716820659139015 0.9249664255209199 0.9862001259471617 0.9676848485892584 0.8941778667889118 0.9655738744784328 0.9608697118653893 1.0869915938591612 0.8818472744657029 1.0 15.973884251110508 -7.545122549000106 24.999833472731282 0.9954377745838726 0.9512636521588841 0.09222727410325227 0.052314391364552904 486.25173347209903 546492.302981721 0.023144745073095642 0.013363829118235011 2.8502138820882734e-08 7.545122549000106 -0.04417412242498853 HRPELIEYDK ddPTM_PC-9_AZD4547_30min_R2 1 HRPELIEYDK 10 1 O43707;K7EJH8 O43707 ACTN4 Alpha-actinin-4 0 85.355 0.0053879 10729000.0 63552.0 73331.0 72477.0 74588.0 70136.0 72329.0 79617.0 83187.0 81044.0 67364.0 False True 83760.21403628151 97033.8116841369 71515.90762436944 57392.88897311249 60398.82703548379 67806.25619601629 86702.7587614339 70332.36059709058 85327.82038539473 65005.606864005866 1.2885075315351024 1.4926991126647773 1.1001498343671088 0.8828913649430353 0.9291325771612342 1.0430831964674907 1.33377354576228 1.0819429890752112 1.312622472149267 1.0 15.988276538398852 -5.278331318036269 21.03841130125217 1.08291451490519 1.390603097504236 0.41614701710397484 0.14455469802906543 90.38141999394715 112568.59662510005 0.040412763275075175 0.08476094759613277 5.2682779748777506e-06 5.278331318036269 0.3076885825990461 HRPELIEYDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HRPELIEYDK 10 1 O43707;K7EJH8 O43707 ACTN4 Alpha-actinin-4 0 90.82700000000001 0.0038125999999999998 9758600.0 53294.0 67482.0 63298.0 62895.0 67243.0 44740.0 64386.0 53755.0 48296.0 43453.0 False True 62315.62159551966 74181.16698699887 64807.26437900176 59371.19705834123 54067.21685791445 42393.755639731324 58286.89196572744 52343.98820813049 49002.237632944605 51330.68492624129 1.2140033137111452 1.4451622278875136 1.2625443138373353 1.1566414347218164 1.0533118140855782 0.8258949924523368 1.1355175184099287 1.0197406927911687 0.9546382968268882 1.0 15.647533890694056 -5.973467380174662 1.908552934941956 0.9953863105158822 1.3312129227774656 0.7075099511583298 0.09008470608130982 0.17851656480912015 1.3119240500191542 0.02890827432871635 0.04762937462099975 1.062998422007532e-06 5.973467380174662 0.3358266122615834 HRPELIEYDK ddPTM_PC-9_Lapatinib_30min_R1 2 HRPELIEYDK 10 1 O43707;K7EJH8 O43707 ACTN4 Alpha-actinin-4 0 ; 79.07 0.0087995 22306000.0 61209.0 71218.0 69140.0 59027.0 73905.0 69523.0 74793.0 66966.0 67628.0 65913.0 False True 60336.14843564413 71053.09909662086 63455.576088118 63368.042488299696 69558.05320282049 66549.66335602853 78665.41557504042 70077.48483140208 60011.02248558884 77305.9742264483 0.7804849371525238 0.9191152405438779 0.8208366393810773 0.8197043387963657 0.8997759086389334 0.8608605482557934 1.0175852042768385 0.906495074056344 0.7762792343810547 1.0 16.238292289868042 -6.574762747476671 2.0579632071856886 0.9150837750724832 0.8410520193322265 0.20707237855774618 0.07130175528019185 0.588167094162483 5.054219931726561 0.026663931708379895 0.027817828953021553 2.6621789953652736e-07 6.574762747476671 -0.07403175574025667 HRPS(ph)AGGPDSAGR ddPTM_PC-9_Lapatinib_30min_R1 2 HRPSAGGPDSAGR 13 1 Q01970-2;Q01970 Q01970-2 PLCB3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1 HRPS(1)AGGPDSAGR;HRPS(1)AGGPDSAGR 66.82600000000001 0.017242 15621400.0 2537.36 1770.67 3503.42 1001.6 3261.3 1762.4 358.41 1432.5700000000002 3043.8700000000003 2201.3 True False 2501.176781105163 1766.5701224046395 3215.3823311922847 1075.2610052396526 3069.4767459624986 1687.0262603550598 376.96671608640156 1499.1324320539054 2701.0373072279094 2581.791771952125 0.9687755644267129 0.6842419057943289 1.2454073043857807 0.4164785932471364 1.1888939996278742 0.6534323482948735 0.14600972866273113 0.5806558252838464 1.0461871234431974 1.0 11.334156932988789 -6.965617520390978 24.957212986007608 0.621332257184219 0.8849924571125743 0.08402944968407422 0.3225767564973543 368.0376123018612 267146.4563814799 0.11129732557825645 0.09815460357524544 1.0823867808739833e-07 6.965617520390978 0.2636601999283553 HRPS(ph)EADEEELAR ddPTM_PC-9_AZD4547_30min_R2 1 HRPSEADEEELAR 13 1 A0A2R8Y611;O14617-3;O14617-4;O14617-2;O14617;O14617-5 A0A2R8Y611 AP3D1 AP-3 complex subunit delta-1 1 HRPS(1)EADEEELAR 90.49799999999999 0.0026330999999999998 9496700.0 15956.0 16514.0 20919.0 32443.0 24506.0 15649.0 16624.0 18562.0 18424.0 17938.0 True False 21029.676094582515 21851.82755112894 20641.600391768214 24963.767589353385 21103.764904351032 14670.46555615949 18103.503795044744 15693.66941232638 19397.855026658523 17309.996079902274 1.2148862424642006 1.2623820046094607 1.1924670748905652 1.4421590550408907 1.2191663595379727 0.8475140888791186 1.045841010678435 0.9066246658800504 1.1206157954697835 1.0 14.079317777534984 -6.62935998248897 6.409418053625283 0.9833709414973086 1.2776908089429266 0.7000191031159331 0.09287739115239081 0.11535346736171762 6.169747880954569 0.02973408396218331 0.029682037215930695 2.3476860399097647e-07 6.62935998248897 0.294319867445618 HRPS(ph)EADEEELAR ddPTM_PC-9_Lapatinib_30min_R1 1 HRPSEADEEELAR 13 1 A0A2R8Y611;O14617-3;O14617-4;O14617-2;O14617;O14617-5 A0A2R8Y611 AP3D1 AP-3 complex subunit delta-1 1 HRPS(1)EADEEELAR 70.45100000000001 0.013294 8808500.0 20543.0 5225.9 9524.6 4773.1 11398.0 13191.0 10666.0 15096.0 18296.0 14671.0 True False 20250.053052875184 5213.799749628336 8741.524154019226 5124.129696594832 10727.592049330186 12626.851679722868 11218.233290861192 15797.415270657462 16235.31181457875 17206.8628021213 1.1768590989392158 0.30300699259283725 0.5080254462737711 0.29779569672416506 0.6234484561594612 0.7338264868460624 0.651962732537054 0.9180880589522642 0.9435370062099423 1.0 14.070696465167288 -7.648357053638902 1.1030323848156696 0.9998316375214802 0.5554493505916852 0.3063548331664572 0.2336973648777018 0.5997082715885331 1.3328742260574213 0.19175831198308194 0.0813570132275665 2.24720631360642e-08 7.648357053638902 -0.444382286929795 HRPS(ph)PPAT(ph)PPPK ddPTM_PC-9_Lapatinib_30min_R1 2 HRPSPPATPPPK 12 1 A9Z1X7;Q8IYB3;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 2 HRPS(1)PPAT(1)PPPK;HRPS(1)PPAT(1)PPPK 82.449 0.028968 100580000.0 1336108.0 1095776.0 1233415.0 1093010.0 1244831.0 1085361.0 1002968.0 1035013.0 1164469.0 1021689.0 True False 1317054.8549078002 1093238.7979962782 1132008.379819587 1173393.6015744717 1171612.488011909 1038942.6401300655 1054896.7754798871 1083103.4824807208 1033314.2388178143 1198286.582334981 1.0991150817539719 0.9123350074286847 0.9446891891368389 0.9792261875185125 0.9777398038864 0.867023511275226 0.8803376346118433 0.9038768341795045 0.8623264701873723 1.0 20.192541553802343 -6.749353811857728 24.834271495955075 0.8953067406979365 0.9764203655220774 0.3174267592075968 0.05772629328015281 244.27749935574334 501957.54053162015 0.018329451288892205 0.01819431113252047 1.7809272870383734e-07 6.749353811857728 0.08111362482414097 HRPS(ph)PPATPPPK ddPTM_PC-9_AZD4547_30min_R2 1 HRPSPPATPPPK 12 1 A9Z1X7;Q8IYB3;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 HRPS(1)PPATPPPK 106.3 0.00079633 7328900.0 30957.0 36425.0 40127.0 52220.0 47976.0 34341.0 33038.0 46613.0 36724.0 40971.0 True False 40800.682054399054 48198.66892030231 39594.88976148396 40181.485790957486 41315.36052604037 32193.651841272465 35978.317996913414 39410.03191018045 38665.15566646808 39536.61776060183 1.0319719886372491 1.2190893316203744 1.0014738742002407 1.0163106524250607 1.0449897554770367 0.8142743022736098 0.9099998946486956 0.9967982630383845 0.9779581020457911 1.0 15.270901837649552 -5.795421384486639 1.302467223380743 0.9461583483811357 1.1212213786961769 0.39117183798400046 0.07580647133580362 0.4541205996624041 1.5399434771545006 0.02678000589863365 0.06405857113688383 1.6016905583816255e-06 5.795421384486639 0.17506303031504122 HRPS(ph)PPATPPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HRPSPPATPPPK 12 1 A9Z1X7;Q8IYB3;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 HRPS(1)PPATPPPK;HRPS(1)PPATPPPK 97.79700000000001 0.0034914 4338300.0 39661.0 33747.0 40248.0 35669.0 54544.0 47111.0 44832.0 35436.0 42976.0 37393.0 True False 46374.823959543435 37097.17913384676 41207.66496139 33670.58157045824 43856.49474738019 44640.41622582438 40585.18840442786 34505.842547545566 43604.44269739583 44172.05489717488 1.0498679327347626 0.839833673579433 0.9328899245759456 0.7622597963540002 0.9928561134289708 1.010603113885912 0.9187978349411944 0.7811690587605528 0.9871499706975292 1.0 15.430846328092466 -4.742596961109765 24.5172110635495 0.9086017033867188 1.0498685241135057 0.17894352212783116 0.08666287276357137 1729.7651887717025 2250569.7716106116 0.0213965437505883 0.7220547521505978 1.8088520186857717e-05 4.742596961109765 0.14126682072678698 HRPS(ph)PPATPPPK ddPTM_PC-9_Lapatinib_30min_R1 1 HRPSPPATPPPK 12 1 A9Z1X7;Q8IYB3;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 HRPS(1)PPATPPPK 72.523 0.011715 6544000.0 30426.0 23403.0 26336.0 26455.0 28964.0 28582.0 27917.0 29388.0 31443.0 21480.0 True False 29992.11966055495 23348.81179137603 24170.755739899883 28400.58895129294 27260.39446541496 27359.614487896233 29362.405661069904 30753.473766168616 27901.558230531264 25192.78937969909 1.1905041243556487 0.926805342571197 0.9594315014349787 1.127330067474734 1.082071304394026 1.0860097337987995 1.1655083213901984 1.2207252362039136 1.1075215931831257 1.0 14.620723247610767 -5.779674600847097 24.78546340515155 1.121742250997277 1.015702828415147 0.17481063767335037 0.08440559880262731 298.1535965404846 405251.93780679593 0.023751700604337973 0.03530791111017388 1.6608308342140817e-06 5.779674600847097 -0.10603942258212995 HRPSAGGPDS(ph)AGR ddPTM_PC-9_AZD4547_30min_R2 1 HRPSAGGPDSAGR 13 1 Q01970-2;Q01970 Q01970-2 PLCB3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1 HRPSAGGPDS(1)AGR 59.15 0.029516000000000004 4298600.0 2789.1 1208.1 3945.0 4802.1 3661.3 4639.4 2866.9 5071.2 2633.8 2699.0 True False 3675.975783116077 1598.594699316876 3892.686722382793 3695.050036705416 3152.991693638313 4349.297584589833 3122.0485460787872 4287.562564582995 2773.017290990732 2604.5088315116627 1.4113892564466877 0.6137797192221645 1.494595324571608 1.4187128075740871 1.210589749395593 1.6699108607228221 1.1987091417412254 1.6462077274257059 1.0646987475873777 1.0 11.346795613728617 -5.296442013680723 24.999521619798337 1.3662287036625533 1.0125838249391972 0.17184919147018496 0.28022570161380794 750.9971719301113 536374.5420906612 0.0666910187042136 0.13883780728489178 5.0531010865080706e-06 5.296442013680723 -0.35364487872335615 HRPSAGGPDS(ph)AGR ddPTM_PC-9_Lapatinib_30min_R1 2 HRPSAGGPDSAGR 13 1 Q01970-2;Q01970 Q01970-2 PLCB3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1 HRPSAGGPDS(1)AGR;HRPS(0.018)AGGPDS(0.982)AGR 60.618 0.026754000000000003 7236100.0 5884.6 2777.0099999999998 5936.9 4528.2 4475.9 5504.4 4640.5 3416.82 5658.4 2258.4 True False 5800.684524896525 2770.580003963987 5448.790999096736 4861.21893363238 4212.636361957975 5268.98964338311 4880.762383859117 3575.577930914665 5021.091406406452 2648.7614308711572 2.189961110611885 1.0459907682409755 2.057109007852274 1.8352800206825581 1.5904174354322547 1.989227712988172 1.8426583560807408 1.3499056159764018 1.8956374658306065 1.0 11.371102193300324 -11.54037580943163 0.4480164080136006 0.23193339387846215 1.7549097692491888 0.32392534179213905 0.32645173217817036 70.57485093077695 4.884996886154815 55.93251635975672 0.1683099736272679 2.881536934403522e-12 11.54037580943163 1.5229763753707266 HRS(ph)EDCGGGPR ddPTM_PC-9_AZD4547_30min_R2 2 HRSEDCGGGPR 11 1 Q9UGU0-2;Q9UGU0;A9JX13 Q9UGU0-2 TCF20 Transcription factor 20 1 HRS(1)EDCGGGPR;HRS(1)EDCGGGPR 120.29 0.00041583 15639600.0 17078.8 15362.4 15055.9 24588.5 21422.4 20236.7 21118.8 18391.2 25260.0 23333.4 True False 22509.503138891683 20327.99537189437 14856.248928649695 18920.00121353807 18448.269537540593 18971.29594992221 22998.33228746335 15549.262627732842 26595.192030687936 22516.504768134208 0.9996890445779829 0.9028042132304185 0.6597937415968106 0.8402725648749011 0.81932208073648 0.8425506598506689 1.021398859382964 0.6905717733659292 1.1811421135098181 1.0 14.458695275127605 -8.271110560337162 24.99278917557092 1.0905710658455667 0.8471783629892949 0.41528158391525816 0.11558394822602802 726.7242178093824 1878018.3792265782 0.10429504373210123 0.028284496701935127 5.3566027466256635e-09 8.271110560337162 -0.2433927028562718 HRS(ph)EDCGGGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HRSEDCGGGPR 11 1 Q9UGU0-2;Q9UGU0;A9JX13 Q9UGU0-2 TCF20 Transcription factor 20 1 HRS(1)EDCGGGPR;HRS(1)EDCGGGPR 68.033 0.018033 10535400.0 5699.54 6574.02 6821.2 7142.030000000001 13769.1 10385.7 5851.59 10008.8 10489.3 9781.699999999999 True False 6664.359550953734 7226.645259415391 6983.8432775450565 6741.885213873669 11071.14369731139 9841.055609020064 5297.285033357111 9746.079605200188 10642.68616869401 11555.04477810541 0.576748916073559 0.6254104071590009 0.604397768391006 0.5834581642338805 0.9581220938484878 0.8516674576343464 0.4584391609969741 0.8434480170658565 0.9210423994946221 1.0 13.496235230097135 -5.509279443919044 0.08711524949439192 1.2955598577482357 5.259664320865379e-18 0.42175122858791114 0.13876996370328054 65.06457145103356 1.188207462130821 5.197646648516947 13.404080143705684 3.0954269262626413e-06 5.509279443919044 -1.2955598577482357 HRS(ph)EDCGGGPR ddPTM_PC-9_Lapatinib_30min_R1 3 HRSEDCGGGPR 11 1 Q9UGU0-2;Q9UGU0;A9JX13 Q9UGU0-2 TCF20 Transcription factor 20 1 HRS(1)EDCGGGPR;HRS(1)EDCGGGPR;HRS(1)EDCGGGPR 89.9 0.0042608 22857470.0 21742.769999999997 28823.809999999998 18809.2 15786.7 30901.64 32730.58 32272.36 47657.88 39682.54 32190.7 True False 21432.71411266432 28757.070238874596 17262.78018161167 16947.706580887392 29084.06629016178 31330.769392108563 33943.26489092977 49872.23908844466 35213.07446952855 37754.819603588476 0.5676815394087383 0.7616794502215375 0.45723381446036354 0.4488885593635989 0.7703404915063462 0.8298482080187366 0.8990445523861958 1.3209502683918124 0.9326775982312376 1.0 15.204373203440666 -6.975828059200577 1.4023395825737957 1.0839046293034857 0.5735604449748546 0.7058514698927911 0.13685914427625856 0.2260059207019526 0.9077780991642386 0.07154710146532547 0.05366210059502102 1.0572359948955155e-07 6.975828059200577 -0.5103441843286312 HRS(ph)EPQHPK ddPTM_PC-9_AZD4547_30min_R2 5 HRSEPQHPK 9 1 A0A087WZ32;A0A087X038;A8K727;Q9HB19 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 HRS(1)EPQHPK;HRS(1)EPQHPK;HRS(1)EPQHPK;HRS(1)EPQHPK;HRS(1)EPQHPK 103.08 0.0012515 13933200.0 151031.9 114206.0 115655.0 98485.2 116588.6 136227.7 118722.3 98071.4 172320.2 194239.0 True False 199056.9025413245 151120.85607994618 114121.33913236555 75780.95872117205 100402.2853557262 127709.36038371931 129288.35470442976 82916.71858657611 181428.69397333948 187438.75173174986 1.0619837184266026 0.8062412637927749 0.6088460261178467 0.4042971798575826 0.5356538305345493 0.6813391532103704 0.6897632080342642 0.4423670015965595 0.9679358846402714 1.0 17.516059726001828 -8.359907813741673 7.654354610940607 0.9936747132981105 0.6475361529422878 0.35581364572070784 0.17762197429674312 0.3531513958064933 24.019486895327166 0.18163264864380155 0.046995720513599785 4.366084998519843e-09 8.359907813741673 -0.3461385603558227 HRS(ph)EPQHPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 HRSEPQHPK 9 1 A0A087WZ32;A0A087X038;A8K727;Q9HB19 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 HRS(1)EPQHPK;HRS(1)EPQHPK;HRS(1)EPQHPK;HRS(1)EPQHPK;HRS(1)EPQHPK 103.08 0.0012515 11062550.0 73901.2 112247.4 90428.8 84632.0 154152.2 116846.4 72985.20000000001 115877.5 130150.3 130713.6 True False 86411.21354476715 123390.58005477702 92584.96554513375 79890.34342064594 123947.18300082689 110718.7690876687 66071.51348891076 112835.83840736015 132053.5019173231 154410.94095171202 0.5596184636410576 0.7991051624597262 0.5996010708469633 0.5173878413552933 0.8027098483881924 0.7170396631563374 0.4278939891284834 0.7307502804652075 0.855208193819759 1.0 17.236415454358557 -8.365863807226068 2.358679263618801 0.9892950450269105 0.6407072239590041 0.5209238730964949 0.11433395192777407 0.22739304696338672 2.4605409488001597 0.10880522038161511 0.030359425905681785 4.306616428499677e-09 8.365863807226068 -0.3485878210679063 HRS(ph)EPQHPK ddPTM_PC-9_Lapatinib_30min_R1 6 HRSEPQHPK 9 1 A0A087WZ32;A0A087X038;A8K727;Q9HB19 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 HRS(1)EPQHPK;HRS(1)EPQHPK;HRS(1)EPQHPK;HRS(1)EPQHPK;HRS(1)EPQHPK;HRS(1)EPQHPK 108.35 0.0010289000000000001 17401580.0 107460.1 149538.19999999998 104657.70000000001 100389.7 151987.0 102283.99999999999 149105.8 207031.3 155193.6 153155.6 True False 105927.69926823137 149191.95348549934 96053.14789640503 107772.69342822212 143047.42347793886 97909.55175564955 156825.76874371734 216650.73000291848 137714.06250694185 179628.34139299058 0.5897048230072054 0.8305590995749242 0.5347326994812034 0.5999759981774658 0.7963521923579974 0.5450673930203653 0.873056932595142 1.2061054971772545 0.7666611039159531 1.0 17.454655467953167 -7.4724526804470655 5.7767076640037365 0.9997874410014884 0.6591794848906648 0.571217546554645 0.1350353601763779 0.13996246043290483 10.962892101708302 0.05535832985851133 0.03604543823648355 3.3693592536931935e-08 7.4724526804470655 -0.3406079561108236 HRS(ph)NSFSDER ddPTM_PC-9_AZD4547_30min_R2 4 HRSNSFSDER 10 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 HRS(0.996)NS(0.004)FSDER;HRS(0.946)NS(0.052)FS(0.002)DER;HRS(0.993)NS(0.007)FSDER;HRS(0.993)NS(0.007)FSDER 107.34 0.0010312000000000001 81675000.0 137106.0 169259.1 332068.0 505054.0 376191.0 377625.0 259298.0 423164.0 331276.0 313069.0 True False 180702.85601803876 223968.7940328986 327664.5613506232 388621.6033065153 323963.3731793331 354012.0490539163 282375.01967321394 357773.72714134725 348786.57304664166 302108.5496007877 0.5981388353849076 0.7413520548453708 1.0845921500189444 1.2863641357387856 1.0723409635623513 1.1718041396766656 0.9346806637758183 1.1842555519005227 1.1545074560370279 1.0 18.204707487010197 -5.189202725362357 3.137189582197478 1.1211229344613718 0.6239648332598099 0.7838896465206748 0.0940373904917429 0.10899250868267345 2.063209751802968 0.024750747372828865 0.08116235230168675 6.468406049892077e-06 5.189202725362357 -0.4971581012015619 HRS(ph)NSFSDER ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 HRSNSFSDER 10 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 HRS(0.749)NS(0.249)FS(0.002)DER;HRS(0.999)NS(0.001)FSDER;HRS(0.997)NS(0.003)FSDER;HRS(0.998)NS(0.002)FSDER;HRS(0.98)NS(0.007)FS(0.013)DER 85.92399999999999 0.0080505 40525500.0 55461.4 62815.200000000004 109210.3 123394.4 194404.3 242180.3 242422.0 187483.1 220910.8 181441.7 True False 64849.91960741842 69051.07792480546 111814.28773436934 116481.01181804256 156312.1729579445 229479.93873394746 219458.03317670932 182561.86727976435 224141.2025278262 214335.64391829338 0.30256245961656186 0.32216329800529275 0.5216784557634937 0.5434514282768859 0.7292868796826536 1.070656912395902 1.0238989146404816 0.8517569170592948 1.0457486138575756 1.0 17.709512263919713 -6.1896765769593785 1.1610412135028063 0.9988297481503697 0.33001257464205647 0.9231726562687165 0.07917002329929874 0.12801215297287702 0.3548612274438501 0.03420126270224418 0.054445102066283696 6.461352326780939e-07 6.1896765769593785 -0.6688171735083133 down HRS(ph)NSFSDER ddPTM_PC-9_Lapatinib_30min_R1 2 HRSNSFSDER 10 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 HRS(0.647)NS(0.325)FS(0.028)DER;HRS(0.994)NS(0.005)FS(0.001)DER 68.626 0.019109 30130000.0 45487.0 26106.9 52953.0 32649.1 56229.0 86320.0 56450.6 75460.7 109676.0 57989.3 True False 44838.34703870579 26046.451077053167 48599.40874449113 35050.22372820482 52921.72077046737 82628.29482174806 59373.335853092845 78966.87960482895 97323.13394051914 68012.67323911475 0.659264588543166 0.3829646716793599 0.7145640132924688 0.5153484205065343 0.778115581259517 1.2148955611735568 0.8729745946663755 1.1610612529109403 1.4309558690386492 1.0 16.05351597761338 -6.582460535230597 3.4113730022942703 1.1298093256248865 0.568467819949318 0.740668747450179 0.15902439372122146 0.12478928265532335 2.965603126414711 0.0548853815752514 0.05610307840792674 2.6154081020626816e-07 6.582460535230597 -0.5613415056755684 HRS(ph)PSGAGEGASCSDGPR ddPTM_PC-9_AZD4547_30min_R2 3 HRSPSGAGEGASCSDGPR 18 1 Q7Z2K8;Q7Z2K8-2 Q7Z2K8 GPRIN1 G protein-regulated inducer of neurite outgrowth 1 1 HRS(0.982)PS(0.018)GAGEGASCSDGPR;HRS(0.997)PS(0.003)GAGEGASCSDGPR;HRS(0.998)PS(0.002)GAGEGASCSDGPR 99.881 0.0002934 6082200.0 15227.400000000001 12742.6 22784.399999999998 35202.9 28532.0 24690.8 20911.399999999998 25258.5 18743.7 20338.1 True False 20069.39645040397 16861.396254875617 22482.26396893751 27087.41528438331 24570.82429816958 23146.880372804826 22772.47408925041 21355.37920758785 19734.453715978052 19626.06930943584 1.0225886872189422 0.8591326153510005 1.1455306518319726 1.3801752585964933 1.2519483097084751 1.1793946107016064 1.1603176229639542 1.088112900799784 1.0055224714044042 1.0 14.260483639688415 -5.328535010327619 7.156929781293064 1.1683357755397408 0.9415796266139965 0.35114799463880175 0.11271962982070202 0.24993325991070076 23.122035750205853 0.03125676112160462 0.06585985641380593 4.6931559926316696e-06 5.328535010327619 -0.22675614892574425 HRS(ph)PSGAGEGASCSDGPR ddPTM_PC-9_Lapatinib_30min_R1 4 HRSPSGAGEGASCSDGPR 18 1 Q7Z2K8;Q7Z2K8-2 Q7Z2K8 GPRIN1 G protein-regulated inducer of neurite outgrowth 1 1 HRS(0.973)PS(0.027)GAGEGASCSDGPR;HRS(0.962)PS(0.038)GAGEGASCSDGPR;HRS(1)PSGAGEGASCSDGPR;HRS(0.999)PS(0.001)GAGEGASCSDGPR 88.95100000000001 0.00070276 5374440.0 28661.3 18835.5 22634.9 17223.899999999998 17912.5 17244.9 14897.7 10663.900000000001 22324.2 9330.9 True False 28252.584606161312 18791.88755699967 20773.94589524073 18490.60306324604 16858.921967329967 16507.375826825344 15669.030010994069 11159.383724480924 19809.813511752254 10943.733632357276 2.5816221003978983 1.7171367824083184 1.89825032234141 1.6896064619642217 1.5405091656729735 1.5083861122147635 1.4317810116161394 1.019705349140264 1.810151286319752 1.0 13.417817400489525 -1.5228787452803376 0.31327671879210106 1.2497715179789473 11.912235414205197 0.6773147619030492 0.24443050759666635 32.404108721745175 0.4627020226096454 0.22342420568861887 196.5157418483368 0.029999999999999995 1.5228787452803376 10.66246389622625 HRSNS(ph)FSDER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HRSNSFSDER 10 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 HRS(0.137)NS(0.846)FS(0.017)DER 60.364 0.032336000000000004 8093300.0 11693.0 5381.6 16980.0 29315.0 34126.0 43438.0 18246.0 18785.0 26735.0 15703.0 True False 13672.393952722854 5915.849682244634 17384.86759700859 27672.575590512304 27439.25527554076 41160.0348117713 16517.60679039952 18291.913654352717 27125.94879734916 18549.829595120398 0.7370630486179468 0.31891665914822315 0.9371982372054644 1.4917967547147537 1.479218724616142 2.2188901844466864 0.8904452035906862 0.9860960479747195 1.4623287323612257 1.0 14.179118313381839 -5.542312154193863 3.864429413081811 1.3791150241337091 0.535913726418855 0.451071774444208 0.36959332242713433 0.19382530439251755 6.3927945617380555 0.1068073191693313 0.20995915872688695 2.868717916570109e-06 5.542312154193863 -0.8432012977148541 HRSNS(ph)FSDER ddPTM_PC-9_Lapatinib_30min_R1 1 HRSNSFSDER 10 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 HRS(0.002)NS(0.915)FS(0.084)DER 67.952 0.019938 6935900.0 48672.0 16074.0 63777.0 23662.0 29428.0 36669.0 12255.0 12064.0 38629.0 9143.1 True False 47977.92835464838 16036.781640583613 58533.50124633944 25402.182414118055 27697.102897674064 35100.75234961399 12889.50393582448 12624.537481797259 34278.19523859659 10723.472652585055 4.474103670426443 1.4954839873366679 5.458446451320884 2.3688392032215866 2.5828482801228816 3.2732635673904036 1.2019897241699282 1.1772807084796288 3.196557341929092 1.0 13.38848455842055 -6.812739136539784 1.0746320851749083 1.6784013408576304 3.474889258458117 0.2925835582677446 1.198330417294774 0.6755133210470528 1.6553115294608876 0.6488932445264242 0.5579975042120114 1.5390788262866274e-07 6.812739136539784 1.7964879176004864 HS(ph)AGSGAEESNSSSTVQK ddPTM_PC-9_AZD4547_30min_R2 1 HSAGSGAEESNSSSTVQK 18 0 Q8IYL3 Q8IYL3 C1orf174 UPF0688 protein C1orf174 1 HS(0.564)AGS(0.436)GAEESNSSSTVQK 139.43 2.3278000000000003e-05 9163300.0 43427.0 41483.0 99348.0 149850.0 104030.0 107400.0 73593.0 112310.0 86428.0 99341.0 True False 57235.88266228595 54891.568505721356 98030.58060717002 115304.39765942137 89587.23018851031 100684.261021888 80142.6344314684 94955.07012705409 90996.40763374092 95863.1018270469 0.5970585300436978 0.57260371779702 1.0226101465403614 1.2028026994938035 0.9345329796457106 1.0502921259896145 0.8360112796689922 0.9905278289280577 0.9492328737485846 1.0 16.54868800131416 -5.26048355464176 24.96447478783275 0.9990070325492808 0.5848310826739732 0.7774195098827975 0.08848380529150021 36.003752249110505 940319.5301112232 0.023882272235955324 0.056241515759364424 5.489293414312453e-06 5.26048355464176 -0.4141759498753076 HS(ph)AGSGAEESNSSSTVQK ddPTM_PC-9_Lapatinib_30min_R1 1 HSAGSGAEESNSSSTVQK 18 0 Q8IYL3 Q8IYL3 C1orf174 UPF0688 protein C1orf174 1 HS(0.549)AGS(0.451)GAEESNSSSTVQK 79.237 0.0023342 6233300.0 25067.0 20351.0 41079.0 22993.0 32041.0 35924.0 29239.0 29452.0 38503.0 24288.0 True False 24709.539983275194 20303.87850986171 37701.64318952565 24683.981922399493 30156.411375029707 34387.61426293417 30752.852352474238 30820.447439812095 34166.38668543539 28486.148438274296 0.8674229875905297 0.7127632067865377 1.3235079242537862 0.8665257774629099 1.0586342144630274 1.207169664844216 1.079572144304155 1.081945055035991 1.1994035192040586 1.0 14.79797295015346 -5.243165776153082 24.934170927760114 1.0980043560521522 0.7900930582393736 0.5086166172688201 0.12261542961186878 618.0036499144329 843257.3787604944 0.02982600893624896 0.07858377758702433 5.712605370760936e-06 5.243165776153082 -0.3079112978127786 HS(ph)CSGSSPPR ddPTM_PC-9_AZD4547_30min_R2 1 HSCSGSSPPR 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 HS(0.54)CS(0.22)GS(0.22)S(0.02)PPR 84.81700000000001 0.012301000000000001 2651300.0 579.18 984.04 1297.5 3875.2 2237.9 2884.8 826.19 3337.1 1890.3 3310.1 True False 763.3471923076146 1302.111686048985 1280.2943022285606 2981.8325112431703 1927.2062139658537 2704.4129999622255 899.7193094578929 2821.42787392923 1990.2173988760649 3194.214406516027 0.2389780694590905 0.4076469267037136 0.40081664512464427 0.9335104447467243 0.6033427843899445 0.8466598217218504 0.281671545786818 0.8832932029151417 0.6230694454373907 1.0 11.641245439250858 -5.627726520187037 7.140316299013229 0.7131144136319986 0.34347012227567325 0.44254609855696536 0.1998422500135213 0.20735747352666184 12.469746900374547 0.05180332120774471 0.09016579253884091 2.356532750281817e-06 5.627726520187037 -0.3696442913563253 HS(ph)DSSLEEK ddPTM_PC-9_AZD4547_30min_R2 1 HSDSSLEEK 9 0 Q5VV41 Q5VV41 ARHGEF16 Rho guanine nucleotide exchange factor 16 1 HS(1)DSSLEEK 147.74 0.00036487 9487800.0 28256.0 27015.0 25958.0 27774.0 29682.0 44991.0 35314.0 40326.0 32308.0 36582.0 True False 37240.820238689106 35747.07044288172 25613.779959344087 21371.133404022476 25561.166648614533 42177.70565768874 38456.87758771715 34094.54329929282 34015.73492191074 35301.2753146942 1.0549426304490357 1.0126283009385204 0.7255766181535748 0.6053926724603832 0.724086209938559 1.1947926889806222 1.089390602602661 0.9658161920598071 0.9635837407764034 1.0 15.10743268363939 -6.752314499164942 24.999879699578116 1.0434972887784093 0.8173042685670615 0.3773617056750601 0.13997954115757621 237.84238213700178 651627.527560149 0.05284153192842292 0.05212600188813231 1.7688275783053659e-07 6.752314499164942 -0.2261930202113478 HS(ph)DSSLEEK ddPTM_PC-9_Lapatinib_30min_R1 2 HSDSSLEEK 9 0 Q5VV41 Q5VV41 ARHGEF16 Rho guanine nucleotide exchange factor 16 1 HS(0.944)DS(0.055)S(0.001)LEEK;HS(0.992)DS(0.008)SLEEK 115.0 0.0020050000000000003 17718900.0 29964.0 49895.0 54493.0 39109.0 64664.0 57848.0 67341.0 69901.0 79546.0 55381.0 True False 29536.70786527538 49779.47119303969 50012.795889063054 41985.206323799495 60860.59065431544 55373.97589027433 70827.58747795635 73148.85564614636 70586.69182348497 64953.532059456025 0.45473597707109426 0.7663859010388139 0.7699780797645187 0.646388348602318 0.9369866229692627 0.8525167782960142 1.0904347343747747 1.12617210068251 1.0867259960377915 1.0 15.98712035858845 -6.49325726988776 0.7345455020852827 1.1027150557574048 0.6094190827704852 0.7720005721153638 0.09855033035885699 0.3321097958249934 0.39857429352677026 0.06343415930224687 0.08510164491099863 3.2117573755031796e-07 6.49325726988776 -0.49329597298691963 HS(ph)EGLREVPDDE ddPTM_PC-9_AZD4547_30min_R2 1 HSEGLREVPDDE 12 1 Q6P9B6 Q6P9B6 TLDC1 TLD domain-containing protein 1 1 HS(1)EGLREVPDDE 61.213 0.02678 6428500.0 25308.0 29902.0 42065.0 60352.0 51754.0 40249.0 35851.0 42322.0 37777.0 37809.0 True False 33355.417560898386 39567.23673451967 41507.19061521725 46438.77882910503 44568.85043906731 37732.22366731823 39041.669547410296 35782.107362809875 39773.81509672596 36485.318418163944 0.9142147857559231 1.0844700950950565 1.1376409036505273 1.2728072781731796 1.2215557482123836 1.0341755342481407 1.0700651999236408 0.9807261910861115 1.0901320536899812 1.0 15.155028424190595 -6.813072236920455 24.922964074709167 1.0360052660661279 1.1326103375355983 0.19271307099867518 0.09276377259047566 178.41962383667303 86120.95622323813 0.03543432027744309 0.031250166040943335 1.5378988177704991e-07 6.813072236920455 0.0966050714694704 HS(ph)EGLREVPDDE ddPTM_PC-9_Lapatinib_30min_R1 1 HSEGLREVPDDE 12 1 Q6P9B6 Q6P9B6 TLDC1 TLD domain-containing protein 1 1 HS(1)EGLREVPDDE 87.719 0.040665 4192000.0 17660.0 13391.0 17943.0 11936.0 20022.0 18744.0 11630.0 14051.0 19741.0 11775.0 True False 17408.165161552646 13359.993962240595 16467.795801982968 12813.813257328758 18844.34532476654 17942.362814398115 12232.144493972968 14703.860755697395 17517.560698054178 13810.293060798736 1.2605210537469813 0.9673939505428498 1.1924291345219673 0.9278451370233018 1.364514514051641 1.2992021773475961 0.8857266417245389 1.0647030219391287 1.2684423582421087 1.0 13.7534563141255 -10.841725283097869 5.008203463932719 0.9999498775971017 1.1292396630756314 0.06014729530336804 0.15970722411500574 8.881945515710353e-05 1.2080296189310367e-05 0.1536631538546931 0.037254353082463686 1.439708991223119e-11 10.841725283097869 0.12928978547852965 HS(ph)FNSFR ddPTM_PC-9_AZD4547_30min_R2 1 HSFNSFR 7 0 P51828 P51828 ADCY7 Adenylate cyclase type 7 1 HS(0.964)FNS(0.036)FR 90.709 0.015746 7234800.0 825.05 5101.1 1636.1 1223.4 1164.1 2928.5 1216.5 2768.7 1364.4 1371.6 True False 1087.3987378939144 6749.93081755262 1614.4042449912502 941.3640313415815 1002.4848088286561 2745.380432054001 1324.7661433272335 2340.861033396619 1436.519398522193 1323.580701482548 0.8215583203018257 5.099750102122218 1.21972482915696 0.7112252621144717 0.7574036155904729 2.0742070574003457 1.0008956324637839 1.7685820220668156 1.0853281533291788 1.0 10.370230446310037 -5.420603602327098 23.547212579929518 1.2196670866175618 3.0104916054490194 0.3143685189579988 1.0379974006018813 23.45584933934731 5393.162000992172 0.24927550508468738 0.5189081945512836 3.796613587454974e-06 5.420603602327098 1.7908245188314575 HS(ph)FNSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HSFNSFR 7 0 P51828 P51828 ADCY7 Adenylate cyclase type 7 1 HS(0.963)FNS(0.037)FR;HS(0.997)FNS(0.003)FR 82.279 0.022713 7221200.0 1460.5 10926.3 5933.0 4819.1 5088.1 4805.9 6031.299999999999 3309.9 4955.4 2971.15 True False 1707.7338038101204 12010.990854598924 6074.4652210278 4549.101450733003 4091.1233302314663 4553.870143696575 5459.971601169383 3223.0186321289384 5027.863350304243 3509.79597538954 0.48656212947551314 3.422133633641159 1.730717472930493 1.2961156382396597 1.1656299565325607 1.2974743191991827 1.5556378887702722 0.9182923038058435 1.4325229687307444 1.0 11.777171453696562 -5.631475965208974 4.480982889714208 1.2494920119799442 2.0878582329879998 0.15174644387776426 0.6840926819483601 0.3055520714064104 10.531043077848917 0.17590704376650546 0.31523520225503737 2.3362753931481024e-06 5.631475965208974 0.8383662210080556 HS(ph)FNSFR ddPTM_PC-9_Lapatinib_30min_R1 2 HSFNSFR 7 0 P51828 P51828 ADCY7 Adenylate cyclase type 7 1 HS(0.995)FNS(0.005)FR;HS(0.999)FNS(0.001)FR 95.35799999999999 0.013152 8430700.0 3666.58 8236.9 3193.6 1407.37 2782.1800000000003 5039.4 1922.8999999999999 2918.55 4491.2 3187.0 True False 3614.293896831579 8217.827964123628 2931.034535652501 1510.8726846486913 2618.5376423763346 4823.8766094151615 2022.45835317804 3054.156487690602 3985.353761567343 3737.868703589433 0.9669397679380266 2.198533072130688 0.7841459312997969 0.40420699721149045 0.7005429698110537 1.2905420152352722 0.5410726040847545 0.8170850101710982 1.0662102062975762 1.0 11.868000178515846 -5.297006497817656 24.60252962352554 0.8058879549776573 1.5827364872404905 0.4052726309751349 0.36632203188443974 382.8988774474049 264858.6142031967 0.091793646958177 0.19109665037325083 5.0465374698967785e-06 5.297006497817656 0.7768485322628332 HS(ph)GPS(ph)S(ph)Y(ph)KVGT(ph)MAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSGPSSYKVGTMAEK 15 1 Q5JXI2;Q13642-5 Q5JXI2 FHL1 5 HS(1)GPS(1)S(1)Y(1)KVGT(1)MAEK 45.115 0.042526 8646900.0 2072.2 2185.4 2863.4 3009.1 2627.4 0.0 2974.2 2407.5 3321.3 1533.1 True False 2422.9825321844087 2402.3520691945564 2931.674315504972 2840.509882633826 2112.5798309487145 0.0 2692.462244656704 2344.305675957104 3369.8677292177185 1811.0388939870777 1.337896463863408 1.3265049564483278 1.6187804277636295 1.5684422306250556 1.1665016350354473 0.0 1.486694876402757 1.2944535226386096 1.8607373593169023 1.0 10.822601814693812 -6.333853668383364 6.817890172766274 1.1082191716584562 1.4636165623659934 0.11056649124115614 0.4534129099656796 0.6049555994086054 48.24440258946882 0.14979584564323398 0.17027894048638642 4.63603100314796e-07 6.333853668383364 0.3553973907075372 HS(ph)GSWPGHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HSGSWPGHR 9 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 HS(0.723)GS(0.277)WPGHR;HS(0.958)GS(0.042)WPGHR 69.672 0.022519 9492400.0 52738.0 49417.0 62936.0 61519.0 63306.0 59485.0 62827.0 61566.0 42737.0 40573.0 True False 61665.50177702029 54322.79317442455 64436.63292610914 58072.28987728903 50901.643745923415 56365.50188264231 56875.57173191006 59949.95773456904 43361.94777453941 47928.5637243087 1.2866127625214943 1.1334116642196141 1.3444307093522976 1.2116426065118153 1.062031485832045 1.1760315248932551 1.1866738185409793 1.2508189913515657 0.9047203672524582 1.0 15.5485980868991 -8.26156073947259 24.999999669274178 0.9523601607276321 1.2023060862227564 0.6336557132987864 0.07723013673826662 6.9592132354668905 1432695.685617216 0.06172791933280082 0.019800667929465828 5.475695137365531e-09 8.26156073947259 0.2499459254951243 HS(ph)HSHSPMSTR ddPTM_PC-9_Lapatinib_30min_R1 1 HSHSHSPMSTR 11 0 P62995 P62995 TRA2B Transformer-2 protein homolog beta 1 HS(0.929)HS(0.054)HS(0.009)PMS(0.004)T(0.004)R 68.069 0.032904 756900.0 634.21 0.0 1182.5 450.24 701.52 2665.9 612.43 652.48 3745.2 1612.1 True False 625.1660491001304 0.0 1085.2794145820023 483.3521515566106 660.2579728413857 2551.8856715164275 644.1386287569953 682.7966027953485 3323.376137295603 1890.7493370117745 0.33064459516784545 0.0 0.5739943382961735 0.25564052415352007 0.34920439209826043 1.349668949533809 0.3406790187085407 0.3611248669664859 1.7577031879582812 1.0 10.88474239770108 -6.853781517384633 0.4275132279703655 1.1424472198724225 0.10098934873447714 0.35924144506414357 0.42290070255382955 1.5375891707064033 0.5970226420976347 0.4285804829135608 0.6255791325804132 1.4002915968399804e-07 6.853781517384633 -1.0414578711379454 HS(ph)ISGPISTSKPLTALSDK ddPTM_PC-9_AZD4547_30min_R2 1 HSISGPISTSKPLTALSDK 19 1 Q69YQ0-2;Q69YQ0;A0A494C1J1 Q69YQ0-2 SPECC1L Cytospin-A 1 HS(0.928)IS(0.055)GPIS(0.013)T(0.003)SKPLTALSDK 73.796 0.014103000000000001 0.0 7597.8 9439.0 12826.0 14006.0 11679.0 15895.0 13496.0 18577.0 13694.0 16803.0 True False 10013.742355942528 12489.972160294676 12655.918859640473 10777.13309054291 10057.572444214302 14901.083137271069 14697.117854783686 15706.351506992089 14417.836883144912 16214.732084435153 0.6175706329156632 0.7702854475334842 0.780519763986057 0.6646507037194958 0.6202737357510069 0.9189842335770024 0.9064052232408912 0.9686469949182158 0.8891813202997589 1.0 13.98501756593028 -6.777175354875021 22.965515931021567 0.9327943594014619 0.6986309795521907 0.8147874970481613 0.05856334086311097 41.25892432027921 60213.54855472625 0.021234308895262476 0.018809393388943142 1.6704160150539494e-07 6.777175354875021 -0.23416337984927127 HS(ph)ISGPISTSKPLTALSDK ddPTM_PC-9_Lapatinib_30min_R1 1 HSISGPISTSKPLTALSDK 19 1 Q69YQ0-2;Q69YQ0;A0A494C1J1 Q69YQ0-2 SPECC1L Cytospin-A 1 HS(0.99)IS(0.002)GPIS(0.002)T(0.003)S(0.003)KPLTALSDK 60.398 0.042178 0.0 6066.0 13342.0 13520.0 9307.5 11210.0 10150.0 11092.0 11436.0 10847.0 9577.3 True False 5979.4977276318405 13311.107418730044 12408.437788709236 9992.004598909803 10550.649839707972 9715.908160805642 11666.289486427175 11967.358309170559 9625.296636026229 11232.723544049919 0.5323283978442822 1.1850293801436131 1.1046686709637845 0.8895442463019277 0.9392779763814941 0.8649645940901173 1.0385984699683026 1.0654013038102217 0.8568978483517331 1.0 13.455420152978403 -4.74583087447401 24.963622644463182 0.9917375737716948 0.5323271115824335 0.6454797947486086 0.10259357545469508 584.151835816119 934217.194286147 0.026627990736198266 0.6490943925447535 1.7954326787229432e-05 4.74583087447401 -0.4594104621892613 HS(ph)LEEGLDMVNR ddPTM_PC-9_AZD4547_30min_R2 6 HSLEEGLDMVNR 12 0 Q7Z309-2;Q7Z309;Q7Z309-5 Q7Z309-2 FAM122B Protein FAM122B 1 HS(1)LEEGLDMVNR;HS(1)LEEGLDMVNR;HS(1)LEEGLDMVNR;HS(1)LEEGLDMVNR;HS(1)LEEGLDMVNR;HS(1)LEEGLDMVNR 135.14 3.3715e-05 26429400.0 59119.2 72819.7 90110.5 106669.0 104307.0 95374.9 82349.4 103109.0 88413.5 91312.0 True False 77917.87584424939 96357.2439581534 88915.57589284514 82078.1100696217 89825.77351987836 89411.09242585202 89678.33706807366 87175.87325910799 93086.85711026234 88115.19467320973 0.8842728672758559 1.0935372079186878 1.0090833507501602 0.9314864521836718 1.0194129837993617 1.0147068591001627 1.0177397598752531 0.9893398474850408 1.0564223055454949 1.0 16.427103199938216 HS(ph)LEEGLDMVNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 HSLEEGLDMVNR 12 0 Q7Z309-2;Q7Z309;Q7Z309-5 Q7Z309-2 FAM122B Protein FAM122B 1 HS(1)LEEGLDMVNR;HS(1)LEEGLDMVNR;HS(1)LEEGLDMVNR;HS(1)LEEGLDMVNR;HS(1)LEEGLDMVNR 106.76 0.0011324000000000002 32891600.0 73985.1 86672.0 102523.0 92405.0 118055.0 92329.0 102576.0 83895.0 86952.0 76529.8 True False 86509.31615766653 95276.22336470692 104967.53714064263 87227.84743105188 94922.9702149082 87487.10470408473 92859.25869407119 81692.84514410011 88223.50850297729 90404.04693043664 0.9569186236124253 1.05389334437671 1.1610933437682516 0.9648666225989998 1.0499858517168899 0.9677343844065254 1.0271582063745859 0.9036414620571184 0.9758800794710306 1.0 16.46409973577166 -6.816440310296671 1.1790546004890163 0.9637724401470181 1.0469747111867493 0.1905684281074741 0.060830677835219414 0.7016459188101952 2.054199790706113 0.03218568329308896 0.02753498683642304 1.5260181172727997e-07 6.816440310296671 0.08320227103973121 HS(ph)LEEGLDMVNR ddPTM_PC-9_Lapatinib_30min_R1 8 HSLEEGLDMVNR 12 0 Q7Z309-2;Q7Z309;Q7Z309-5 Q7Z309-2 FAM122B Protein FAM122B 1 HS(1)LEEGLDMVNR;HS(1)LEEGLDMVNR;HS(1)LEEGLDMVNR;HS(1)LEEGLDMVNR;HS(1)LEEGLDMVNR;HS(1)LEEGLDMVNR;HS(1)LEEGLDMVNR;HS(1)LEEGLDMVNR 149.82 4.8205e-05 32433500.0 83007.3 95817.6 102135.40000000001 88849.6 100014.8 94395.59999999999 85196.7 85581.77 102209.7 69006.5 True False 81823.60068032549 95595.74023421577 93738.22166604521 95383.89597757699 94132.1261006624 90358.52023489108 89607.76825534539 89558.21146581163 90697.76727014378 80934.18157961842 1.010989412425603 1.1811540979156518 1.1582031205669374 1.1785366098221894 1.1630700930491351 1.1164444795923651 1.1071683991416457 1.1065560893787427 1.1206361206101838 1.0 16.304461515831854 -9.43575961312411 0.5296211140077097 0.9897259253982261 1.139728242612603 0.3979296575714043 0.04706713293455008 3.6400919903128837 1.3271364382897646 0.1302233997115108 0.022240369827686512 3.6664045810700784e-10 9.43575961312411 0.15000231721437685 HS(ph)LTGHSDIR ddPTM_PC-9_AZD4547_30min_R2 1 HSLTGHSDIR 10 0 H0Y4E8;Q9Y2K2-7;Q9Y2K2;Q9Y2K2-8;Q9Y2K2-6 H0Y4E8 SIK3 Serine/threonine-protein kinase SIK3 1 HS(0.999)LT(0.001)GHSDIR 78.705 0.018609 0.0 16955.0 11393.0 18865.0 27187.0 35636.0 22294.0 19137.0 40632.0 31205.0 25181.0 True False 22346.337314091666 15075.564447742046 18614.837773827963 20919.457184962877 30688.55652213556 20899.952655698104 20840.15592671867 34353.2580304733 32854.43259372988 24299.42085449988 0.9196242761462139 0.6204083849574663 0.76606096438635 0.8609035297682378 1.262933660266743 0.8601008551126745 0.8576400257234688 1.4137480163076233 1.3520664871173562 1.0 14.56863430900611 -6.5246853755119965 0.6400517640246164 1.2173298694235666 0.7235908167197027 0.3902224584571875 0.195686634760556 0.8578777200107026 0.7761488116718404 0.15160344406010695 0.21126908012787704 2.987546161923536e-07 6.5246853755119965 -0.49373905270386387 HS(ph)PQQPSNGSLR ddPTM_PC-9_AZD4547_30min_R2 1 HSPQQPSNGSLR 12 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 HS(1)PQQPSNGSLR 105.19 0.0010317 30404000.0 23948.0 20818.0 34521.0 37261.0 32946.0 28078.0 19800.0 32024.0 24662.0 32377.0 True False 31562.965850655677 27547.011381821638 34063.2289843793 28671.052126711365 28372.016589355655 26322.27822134616 21562.161642317482 27075.42663831161 25965.58297152913 31243.491084791825 1.010225322291828 0.8816880068575468 1.0902504106194464 0.9176648041315515 0.9080936734104629 0.8424883810170264 0.6901329170866294 0.8665941512371812 0.831071755107681 1.0 14.931268045875624 -6.417132179081882 2.0109187552492744 0.8292043851892413 0.9807258125011806 0.3248065330356159 0.0870113904921085 0.3531287760970336 2.8265336698733527 0.030395819333763226 0.03538724006451133 3.8270824696326403e-07 6.417132179081882 0.1515214273119393 HS(ph)PQQPSNGSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HSPQQPSNGSLR 12 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 HS(1)PQQPSNGSLR;HS(1)PQQPSNGSLR;HS(1)PQQPSNGSLR 86.214 0.0052386 69984320.0 42159.3 45799.2 57133.0 59572.0 72465.4 53279.2 51202.6 41601.9 43179.0 39485.2 True False 49296.036805869204 50345.841899631785 58495.26739810911 56234.373975029856 58266.32506722651 50485.14495932885 46352.31905327798 40509.89420585664 43810.411188357546 46643.55419532879 1.056867077483689 1.0793740478866374 1.2540911259281187 1.205619403262832 1.249182787898734 1.0823605925893354 0.9937561545839494 0.8684993008082901 0.9392597100318103 1.0 15.509390104293054 -7.214461807135258 2.5179359424948204 0.9305908500512753 1.1700387414883893 0.6905256132334865 0.0688394246053617 0.1713798741266821 2.1366227512100022 0.033680250572807324 0.023231261029294265 6.102927248434959e-08 7.214461807135258 0.23944789143711398 HS(ph)PQQPSNGSLR ddPTM_PC-9_Lapatinib_30min_R1 1 HSPQQPSNGSLR 12 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 HS(1)PQQPSNGSLR 69.878 0.037888 0.0 10871.0 11390.0 14357.0 11793.0 12102.0 14173.0 11321.0 11552.0 15590.0 10226.0 True False 10715.977546502758 11363.627154799518 13176.622879622666 12660.296560294742 11390.18415344745 13566.853828876678 11907.145985921577 12088.748092649366 13834.09003002202 11993.550474711505 0.8934783381366077 0.9474781615969196 1.0986423834548142 1.055592052327547 0.9496924349018868 1.1311791164328273 0.9927957539369087 1.0079374008671234 1.153460775371839 1.0 13.549971185424937 -5.0738028402474855 4.613549446802647 1.0462922950836206 0.9036535874768148 0.4223248552223473 0.06129049535286917 0.18231417728713042 7.126737292644936 0.015170845760507045 0.04655944698609599 8.437176993546845e-06 5.0738028402474855 -0.14263870760680586 HS(ph)PSPRPR ddPTM_PC-9_AZD4547_30min_R2 1 HSPSPRPR 8 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 HS(0.999)PS(0.001)PRPR 70.399 0.018045 469820.0 2282.7 1064.9 930.86 841.82 0.0 967.52 817.51 1137.0 2710.9 3063.1 True False 3008.551116890417 1409.1080997455012 918.5161881868808 647.7514049893493 0.0 907.0208214515577 890.266806273281 961.3027756607637 2854.19263958796 2955.8618013350783 1.0178253650192781 0.47671650247959746 0.3107439555435282 0.21914130244410565 0.0 0.3068549487130563 0.301186884268802 0.32521912060522273 0.9656042235461761 1.0 11.529363103811459 -8.264293338936284 19.99190421752148 0.9828043891762077 0.34959011205663054 0.4955992900788322 0.24673736938674531 13.50370838335755 94543.97466555864 0.21478082053143743 0.06576913861359354 5.441349993123309e-09 8.264293338936284 -0.6332142771195772 HS(ph)PSPRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HSPSPRPR 8 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 HS(0.982)PS(0.018)PRPR;HS(0.995)PS(0.005)PRPR 60.102 0.040116000000000006 0.0 1303.8400000000001 1809.7199999999998 1616.1200000000001 1244.15 4012.9 5253.3 1093.21 1997.1799999999998 4608.6 7980.299999999999 True False 1524.5543599861605 1989.3770415771828 1654.6544299692312 1174.4443090887232 3226.6010518436838 4977.807700093887 989.6532346449997 1944.7561411871268 4675.9920563853875 9427.065217979958 0.16172099425793976 0.21102824639240894 0.17552169118479827 0.1245821771603681 0.342269940563229 0.5280336546945559 0.10497999236893618 0.20629497051510282 0.4960177900824329 1.0 13.202592993584718 -14.52287873798754 0.21371097318074794 4.686107746095528 0.15560571024055797 0.7732918422870976 0.12507544976834709 72.7198648219668 0.724218397413098 114.77630776771989 0.27020749375509184 3.000000050376862e-15 14.52287873798754 -4.53050203585497 HS(ph)PSPRPR ddPTM_PC-9_Lapatinib_30min_R1 4 HSPSPRPR 8 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 HS(0.998)PS(0.002)PRPR;HS(0.998)PS(0.002)PRPR;HS(1)PSPRPR;HS(1)PSPRPR 101.46 0.0021606 1972350.0 4439.53 5447.83 1128.28 5373.52 7870.51 4420.51 13526.7 11190.3 4017.9800000000005 6873.93 True False 4376.22148808991 5435.215884348676 1035.5171736867496 5768.7065863372345 7407.582075818017 4231.455092012109 14227.046339348584 11710.242190198607 3565.4327811948597 8062.0796415640125 0.5428154623440237 0.6741704530339103 0.12844293528783143 0.7155357975622935 0.9188177747126515 0.5248590041453899 1.7646869011317026 1.4525088700223836 0.4422472785822269 1.0 12.976936319639957 -6.6981535818313915 1.4741828264098302 1.1618302024548426 0.504470709218788 0.3061674412551564 0.38637450841565113 0.4681290676139078 2.1178190519183406 0.17330311882337587 0.1655922988319295 2.0037633007504145e-07 6.6981535818313915 -0.6573594932360546 HS(ph)PTEDEESAK ddPTM_PC-9_AZD4547_30min_R2 2 HSPTEDEESAK 11 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 HS(0.959)PT(0.041)EDEESAK;HS(0.606)PT(0.394)EDEESAK 128.21 0.00030045 10065100.0 45336.4 63617.0 51570.0 35347.9 41165.0 64947.0 69163.0 70567.0 59673.0 45527.0 True False 59752.43214429872 84179.95115176031 50886.148104760585 27198.987774610992 35449.95030962258 60885.85382298489 75318.37301351523 59662.49161834049 62827.19295515599 43933.113587340325 1.3600773372346835 1.9160934492932782 1.1582640962516217 0.6190999351898563 0.8069073055600086 1.3858761387795113 1.7143873234429443 1.3580301223069404 1.4300646556783114 1.0 15.423021127963429 -6.9710825362955156 24.986838830169603 1.4261246205313958 1.1733783198478214 0.06857676075034691 0.36021746502099655 570.9566883946136 493347.4183379267 0.14190235811529922 0.1251442743773715 1.0688517280218693e-07 6.9710825362955156 -0.2527463006835744 HS(ph)PTEDEESAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSPTEDEESAK 11 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 HS(0.949)PT(0.051)EDEESAK 154.1 0.00028011 5225300.0 47485.0 122890.0 70942.0 46341.0 67385.0 40568.0 66946.0 30880.0 36153.0 43755.0 True False 55523.27262849954 135089.70704828383 72633.52632903306 43744.6640095491 54181.39297727 38440.54266411756 60604.39023293251 30069.43272006454 36681.66923024365 51687.4351356106 1.0742121848922273 2.613588905966285 1.4052453200370052 0.8463307164454511 1.0482507563998114 0.743711553170754 1.172516881016185 0.5817551720485331 0.7096825202102441 1.0 15.657525993345494 -5.572113256769532 4.338154443712202 0.8740966934303271 1.8836330511226882 0.512366817543035 0.3831874631781773 0.13830861798224864 5.532239462730921 0.09847740195058753 0.18297540242536206 2.678469733424664e-06 5.572113256769532 1.009536357692361 HS(ph)PTGPPGFPR ddPTM_PC-9_AZD4547_30min_R2 2 HSPTGPPGFPR 11 0 P98175-5;P98175-2;P98175 P98175-5 RBM10 RNA-binding protein 10 1 HS(0.62)PT(0.38)GPPGFPR;HS(0.715)PT(0.285)GPPGFPR 84.169 0.013659000000000001 4628900.0 18447.7 22644.0 25899.0 31173.0 26459.0 28526.0 24899.9 32521.0 26890.0 27196.0 True False 24313.684864002862 29963.230172445456 25555.562337894018 23986.546468048964 22785.624565584916 26742.26471052499 27115.9428625021 27495.626708235413 28311.350502976962 26243.87631781814 0.9264517394290269 1.1417227321751278 0.9737723965930751 0.913986416395486 0.8682263355324052 1.0189906546834497 1.033229334497811 1.0476968560306545 1.0787792992209433 1.0 14.679693206649798 -6.986181646378345 24.983169127963656 1.0413595459751557 0.9694588686122297 0.2102959022281471 0.06934362904870814 423.6471193370011 765938.4672863276 0.026393495217040118 0.023266612249728685 1.0323295371780974e-07 6.986181646378345 -0.07190067736292594 HS(ph)PTGPPGFPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HSPTGPPGFPR 11 0 P98175-5;P98175-2;P98175 P98175-5 RBM10 RNA-binding protein 10 1 HS(0.814)PT(0.186)GPPGFPR;HS(0.616)PT(0.384)GPPGFPR 70.563 0.018084 4987900.0 23818.0 27473.0 24934.0 27380.0 31929.0 20659.0 25482.0 22582.0 21725.0 17862.5 True False 27849.916973056774 30200.33787726827 25528.52112272159 25845.987367157682 25672.741654244288 19575.605671909016 23068.160486296205 21989.24642760677 22042.687025337967 21100.829850527807 1.3198493694483844 1.431239344196354 1.209834935571647 1.2248801374279212 1.2166697630426189 0.9277173367387426 1.0932347518891152 1.0421033951447525 1.0446360252881999 1.0 14.36501211770934 -6.062690742316305 0.8934675149595144 1.024707452567693 1.3789956067424916 0.7765699955633776 0.07002125766721941 0.29414306081253594 0.4822068904353689 0.03245223043891273 0.06812254908101102 8.655840749793615e-07 6.062690742316305 0.35428815417479864 HS(ph)PTGPPGFPR ddPTM_PC-9_Lapatinib_30min_R1 1 HSPTGPPGFPR 11 0 P98175-5;P98175-2;P98175 P98175-5 RBM10 RNA-binding protein 10 1 HS(0.715)PT(0.285)GPPGFPR 84.169 0.0068885000000000005 3665300.0 10766.0 17579.0 20423.0 13506.0 17415.0 19097.0 14871.0 14532.0 18578.0 16706.0 True False 10612.4748657574 17538.296905550542 18743.89977505981 14499.276294695232 16390.68393920735 18280.265827281295 15640.947615638173 15207.209771674228 16485.550004987123 19593.60984065424 0.5416293859101894 0.8951028956982094 0.9566333068533706 0.7400002558288715 0.8365321179968976 0.9329707989465053 0.79826778949049 0.7761310904599728 0.8413738019209563 1.0 14.25809559744288 -13.070813605487439 0.022385102431549054 1.9774144529430693 5.93972780191635e-06 0.23362140895202899 0.1090186969826305 3900.3633649516323 8.456883629809662 484.3372817018608 285.73287360097635 8.495450123693139e-14 13.070813605487439 -1.9774085132152674 HS(ph)PTLPEPGGLR ddPTM_PC-9_AZD4547_30min_R2 2 HSPTLPEPGGLR 12 0 S4R446;Q86XN8;Q86XN8-2;Q86XN8-3 S4R446 MEX3D RNA-binding protein MEX3D 1 HS(0.894)PT(0.106)LPEPGGLR;HS(0.977)PT(0.023)LPEPGGLR 71.529 0.015406999999999999 12644100.0 51112.0 71557.0 111836.0 88248.0 92339.0 126512.0 93213.0 146035.0 110872.0 97192.0 True False 67364.55280435584 94686.40087659779 110352.9815676556 67903.78701800878 79519.32373716096 118601.18464060623 101508.77642249217 123468.64630045672 116732.46757032604 93789.33766294224 0.7182538493495804 1.0095646609306421 1.1766047646507471 0.7240032684956119 0.8478503603782287 1.2645486960024408 1.0823061443006652 1.3164465106276284 1.244624074325338 1.0 16.517136300422983 -6.760288398794203 24.99999870027287 1.1951580768325505 0.907722389659638 0.47055654179259 0.1512284444764349 28.897689522718892 627679.631815309 0.05237426946740936 0.049600922285272644 1.7366472030094554e-07 6.760288398794203 -0.28743568717291246 HS(ph)PTLPEPGGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSPTLPEPGGLR 12 0 S4R446;Q86XN8;Q86XN8-2;Q86XN8-3 S4R446 MEX3D RNA-binding protein MEX3D 1 HS(0.995)PT(0.005)LPEPGGLR 69.878 0.017625 5689100.0 16344.0 18445.0 29692.0 23996.0 29111.0 18755.0 23307.0 15545.0 22894.0 23686.0 True False 19110.716391285594 20276.0977012417 30399.969887537052 22651.58191608165 23406.908525062034 17771.45478370944 21099.192231932564 15136.960221288964 23228.78143880723 27980.08430172715 0.6830113942904 0.7246617802359552 1.0864860005321901 0.8095608888027337 0.8365560400980341 0.6351465775466747 0.7540789371613922 0.5409905151842088 0.8301898303206101 1.0 14.77211268878194 -6.722560578584488 23.35314409719934 0.7235179541487837 0.8356412073162246 0.042076791525846424 0.1513596329993408 184.07075329064196 110563.48048076975 0.04929914894447007 0.049297650553866035 1.8942592707301516e-07 6.722560578584488 0.11212325316744087 HS(ph)PTLPEPGGLR ddPTM_PC-9_Lapatinib_30min_R1 2 HSPTLPEPGGLR 12 0 S4R446;Q86XN8;Q86XN8-2;Q86XN8-3 S4R446 MEX3D RNA-binding protein MEX3D 1 HS(0.694)PT(0.306)LPEPGGLR;HS(0.833)PT(0.167)LPEPGGLR 75.483 0.024197999999999997 0.0 35967.1 39337.0 102628.0 47068.0 80050.0 89188.0 57003.0 68080.0 117510.0 61405.0 True False 35454.20255844168 39245.917593358055 94190.32199553627 50529.537734245154 75341.61638435523 85373.63714738247 59954.33642217892 71243.24533825909 104274.78636484216 72018.77243298061 0.49229112578161105 0.5449401075237655 1.307857921116166 0.7016162040427313 1.0461385808049812 1.1854358837736323 0.832482065394427 0.9892315979775522 1.447883417644732 1.0 16.136085388409153 -5.199188312383981 8.928170144604001 1.045785594961197 0.5154068928091678 0.5294511660462262 0.20504620578296395 0.3312728279168195 44.97529759979334 0.050871053634583545 0.13523057280112877 6.321376936955596e-06 5.199188312383981 -0.5303787021520291 HS(ph)PTPQQSNR ddPTM_PC-9_AZD4547_30min_R2 4 HSPTPQQSNR 10 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 HS(0.742)PT(0.258)PQQSNR;HS(1)PTPQQSNR;HS(0.997)PT(0.003)PQQSNR;HS(0.991)PT(0.009)PQQSNR 128.21 0.00016269999999999997 43747700.0 40597.6 29091.199999999997 26494.3 28849.4 27404.7 30394.4 25456.6 24443.600000000002 45469.3 47693.2 True False 53506.79231746195 38494.36149057787 26142.968270931895 22198.616548786846 23600.030444555156 28493.83336316274 27722.18808403128 20666.40327804875 47872.714370584305 46023.47558468025 1.1625978185635475 0.8364070944566259 0.5680355066368359 0.48233246765431287 0.5127824473215329 0.6191152015613404 0.6023488607031476 0.4490404737039881 1.0401803375866643 1.0 15.49008231616332 -10.508292737715731 20.470893112838404 0.9999999999981523 0.6731936081804177 0.12716724460579942 0.23070336031751207 0.0 0.0 0.22906246343756836 0.05555580774219283 3.1024676539877493e-11 10.508292737715731 -0.3268063918177345 HS(ph)PTPQQSNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HSPTPQQSNR 10 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 HS(0.982)PT(0.017)PQQSNR;HS(0.998)PT(0.002)PQQSNR;HS(0.977)PT(0.023)PQQSNR;HS(1)PTPQQSNR 138.42 0.00011916 30782700.0 12412.14 19514.9 16787.8 12507.21 32505.5 27152.199999999997 14238.220000000001 22585.5 29967.5 33097.8 True False 14513.270151060424 21452.210302518928 17188.08482008604 11806.47157262192 26136.280617684188 25728.290833283703 12889.472725814006 21992.654556315334 30405.71799455996 39098.16913795937 0.3712007613412741 0.548675571657179 0.43961354710593303 0.3019699344734619 0.668478376198674 0.6580433662379549 0.3296694707195371 0.5624983225867539 0.7776762611894238 1.0 15.25481343113758 -8.423459399160368 2.140105470827427 0.9945824942490772 0.4814897353590992 0.6697905794491734 0.11942708722246427 0.1800722914104648 1.7329075140351706 0.1169400842661341 0.03272965833510555 3.7717300409366885e-09 8.423459399160368 -0.513092758889978 HS(ph)PTPQQSNR ddPTM_PC-9_Lapatinib_30min_R1 4 HSPTPQQSNR 10 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 HS(1)PTPQQSNR;HS(1)PTPQQSNR;HS(0.996)PT(0.004)PQQSNR;HS(0.969)PT(0.031)PQQSNR 110.98 0.0009417999999999999 68575000.0 24148.399999999998 42320.5 26391.3 34527.1 43653.8 25239.3 50458.4 57747.1 48376.799999999996 37640.4 True False 23804.039387725803 42222.50948241376 24221.509187364045 37066.33811302916 41086.16931067294 24159.873974681934 53070.889057152664 60430.241082153094 42928.09535371196 44146.49298731963 0.5392056713216864 0.9564182027900041 0.5486621370880193 0.8396213516592557 0.9306779889055804 0.5472659851286821 1.202154134245645 1.3688571162268928 0.9724010323094603 1.0 15.430011213781896 -7.275369201239783 24.970241404925307 1.1665912026363738 0.7436788043733774 0.5564426728776644 0.17762015430893163 565.489144800813 1013677.409166826 0.07068158694966724 0.047927416197975456 5.3043332197660075e-08 7.275369201239783 -0.4229123982629964 HS(ph)S(ph)ETFSSTTTVTPVSPSFAHNPK ddPTM_PC-9_AZD4547_30min_R2 1 HSSETFSSTTTVTPVSPSFAHNPK 24 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 2 HS(0.242)S(0.143)ET(0.13)FS(0.275)S(0.284)T(0.181)T(0.136)T(0.114)VT(0.158)PVS(0.278)PS(0.059)FAHNPK 54.855 0.027669 0.0 11628.0 10016.0 21027.0 25654.0 29664.0 24149.0 16990.0 26243.0 19045.0 16135.0 True False 15325.462122574916 13253.476126444686 20748.16824120226 19739.866650348977 25545.66563791191 22638.95921245417 18502.0770860088 22187.747354147246 20051.679818861907 15570.118561111773 0.9842867966883749 0.8512122803962985 1.3325632788065778 1.2678045175360224 1.6406853639326326 1.4540004383137886 1.1883067565214271 1.4250210919757407 1.2878309012330431 1.0 13.92649230963607 -5.268673179629056 23.33084502894249 1.3487305850754816 0.9177495159724522 0.49168059003009434 0.16397012282292664 149.78073687363312 483085.65295194293 0.04201949023769179 0.09072253609869932 5.386750000488383e-06 5.268673179629056 -0.43098106910302936 HS(ph)SADNLANEMTYITETEDVFYTYK ddPTM_PC-9_AZD4547_30min_R2 2 HSSADNLANEMTYITETEDVFYTYK 25 0 J3KN34;P26045-2;P26045;P26045-3 J3KN34 PTPN3 Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 3 1 HS(0.499)S(0.499)ADNLANEMT(0.001)Y(0.001)ITETEDVFYTYK;HS(0.499)S(0.499)ADNLANEMT(0.001)Y(0.001)ITETEDVFYTYK 77.053 0.00011420000000000001 3194000.0 11950.7 9585.599999999999 14353.8 20213.0 16372.800000000001 15083.5 13434.3 17401.0 11536.0 15148.8 True False 15750.774009997947 12683.957743375418 14163.45923339368 15553.205137736955 14099.719335099931 14140.32636055541 14629.926674312417 14712.075285200473 12145.769408789229 14618.44512293586 1.0774589142374316 0.8676680479153495 0.9688759039886997 1.0639438741220493 0.9645156661003526 0.9672934598474978 1.000785415362578 1.0064049330470661 0.8308523448730478 1.0 13.835502248109018 -8.208507765959325 24.999088884191266 0.915424855552065 0.9861307120092244 0.16374924862921036 0.06669347712835212 509.95114145138007 240845.3431888549 0.04296762128383366 0.01624021434504337 6.187172636869767e-09 8.208507765959325 0.07070585645715943 HS(ph)SEDFR ddPTM_PC-9_Lapatinib_30min_R1 1 HSSEDFR 7 0 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 1 HS(0.902)S(0.098)EDFR 80.455 0.025381 9489600.0 66217.0 110120.0 84104.0 74667.0 96168.0 87292.0 83438.0 100730.0 83516.0 78586.0 True False 65272.73343728933 109865.0239057524 77189.29377082862 80158.26026181005 90511.58731356246 83558.72464759061 87758.01137473059 105410.28353294425 74109.54861753169 92169.48539073717 0.7081815978528735 1.1919891213452907 0.8374712459725415 0.8696832788204519 0.9820125058727807 0.9065768816366645 0.952137369571883 1.1436570692141212 0.8040573114123032 1.0 16.492001575301018 -7.531120147325362 24.990068871919302 0.9938937284902027 0.926150580922386 0.04033581932064967 0.13828994258339403 682.3785844841387 2069116.8018836074 0.06093961428728387 0.03525982816244722 2.9436071738667766e-08 7.531120147325362 -0.06774314756781674 HS(ph)SETFSSTPSATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSSETFSSTPSATR 14 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 HS(0.887)S(0.112)ET(0.001)FSSTPSATR 85.163 0.007002199999999999 8062200.0 5630.5 7126.0 8505.4 10681.0 13053.0 11974.0 14536.0 10541.0 10151.0 9425.6 True False 6583.632442555891 7833.422185906657 8708.200992909124 10082.578198269219 10495.358351744517 11346.062360977707 13159.044848473497 10264.309919112702 10299.43917119473 11134.386666991448 0.5912882891047301 0.7035342331993287 0.7820997467893858 0.9055351228424303 0.9426076770675328 1.0190109882400424 1.1818383214123747 0.9218567870955892 0.9250118106395596 1.0 13.44273446961406 -5.515984744876603 0.9809106038030306 1.0128143779571204 0.5731579337838767 0.8086478598702038 0.06975375265249796 0.3603589951884764 0.5630329168190286 0.028351296347485937 0.13147850502789205 3.048002052537439e-06 5.515984744876603 -0.4396564441732437 HS(ph)SETFSSTPSATR ddPTM_PC-9_Lapatinib_30min_R1 1 HSSETFSSTPSATR 14 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 HS(0.571)S(0.429)ETFSSTPSATR 115.8 0.00015372 3682100.0 10138.0 5015.7 7505.3 5684.2 7069.1 7181.0 5462.0 6340.4 7925.9 3998.9 True False 9993.430260918496 5004.0864548136915 6888.243205295814 6102.235029935337 6653.30943638534 6873.885369728597 5744.795634228743 6634.998130768187 7033.201678572899 4690.10453680069 2.1307478719302533 1.0669456118833507 1.468675836806521 1.3010872107549907 1.4185844652673416 1.4656145328516605 1.2248758186843105 1.4146802227342652 1.4995831379422795 1.0 12.195404363701927 -1.5228787453736279 0.03285865189802688 9.32071700984341e-10 3.477473265561881 0.24468246819510864 0.255586480321521 1977.9884555011445 4.993359628679041 161.5015792772218 424.9226553905187 0.029999999993555734 1.5228787453736279 3.4774732646298094 HS(ph)SLSEMSPPDTPSLSPQITR ddPTM_PC-9_Lapatinib_30min_R1 1 HSSLSEMSPPDTPSLSPQITR 21 0 A0A2R8YEQ5;Q5QGS0 A0A2R8YEQ5 KIAA2022 Protein KIAA2022 1 HS(0.714)S(0.198)LS(0.067)EMS(0.02)PPDTPSLSPQITR 50.966 0.039080000000000004 7649700.0 12396.0 11303.0 14537.0 13885.0 15684.0 16598.0 14009.0 14918.0 16010.0 9651.5 True False 12219.230766852012 11276.828597954252 13341.823974442754 14906.149219002165 14761.497955930396 15888.142231827771 14734.31747343656 15611.144740836506 14206.785207225941 11319.748915184633 1.0794612900345155 0.9962083684406811 1.1786325009864531 1.3168268422461769 1.3040481786772586 1.4035772657920853 1.3016470227242876 1.3791069800051194 1.2550441987426555 1.0 13.46655433746877 -5.516040294141894 3.1657346439692127 1.3025705823163871 1.039468388737604 0.4373409585628615 0.10694560783346627 0.1885261487545551 3.863885626007367 0.027634042534545666 0.0588921054039409 3.0476122169445193e-06 5.516040294141894 -0.2631021935787832 HS(ph)SNPPLESHVGWVMDSR ddPTM_PC-9_AZD4547_30min_R2 1 HSSNPPLESHVGWVMDSR 18 0 Q6PKG0;Q6PKG0-3;H0YC33;H0YBR8 Q6PKG0 LARP1 La-related protein 1 1 HS(0.5)S(0.5)NPPLESHVGWVMDSR 64.538 0.013668000000000001 3711600.0 3268.6 8558.4 29808.0 61250.0 35961.0 17919.0 14546.0 44533.0 10802.0 18420.0 True False 4307.946808896493 11324.735431366234 29412.726443798805 47129.75880306676 30968.435882043905 16798.522097311117 15840.565820664147 37651.4481165354 11372.971667279931 17775.12140661165 0.24235822137867957 0.6371115657839543 1.6547131111497455 2.651445113929648 1.7422348446253006 0.945058079381822 0.8911649860671036 2.118210461422251 0.6398252595366032 1.0 14.117571793240463 -5.129720296439055 3.9493067791934613 1.5078745805111713 0.3242764222292398 0.32600818166122747 0.5903805764729689 0.2622921659493516 6.888846411670177 0.15958932480164253 0.49932608644918886 7.417878294520068e-06 5.129720296439055 -1.1835981582819315 HS(ph)SNPPLESHVGWVMDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HSSNPPLESHVGWVMDSR 18 0 Q6PKG0;Q6PKG0-3;H0YC33;H0YBR8 Q6PKG0 LARP1 La-related protein 1 1 HS(0.5)S(0.5)NPPLESHVGWVMDSR;HS(0.532)S(0.464)NPPLES(0.004)HVGWVMDSR 66.041 0.033811 5909000.0 22732.4 20963.4 27412.0 29043.0 29963.0 31137.0 28056.5 27381.0 24702.1 23340.2 True False 26580.54633463414 23044.507809715928 28065.606040588904 27415.814868676425 24091.965241195216 29504.12090644422 25398.785208530317 26662.27776256759 25063.3214807181 27571.59349907847 0.9640554992050984 0.8358061644310166 1.017917446139881 0.9943500316582263 0.8737966212217819 1.070091248350602 0.9211939530944856 0.9670198337814145 0.9090269476646605 1.0 14.750895029805914 -5.268537699723819 24.99135881664386 0.967379996045418 0.8999308307260155 0.16967526189318383 0.061167998077941134 849.2697990839365 2990069.053801006 0.015164885713303036 0.032736062425734395 5.388430680886847e-06 5.268537699723819 -0.06744916531940248 HS(ph)SPAPAQPK ddPTM_PC-9_AZD4547_30min_R2 2 HSSPAPAQPK 10 0 I3L4X5;Q70CQ4 I3L4X5 USP31 Ubiquitin carboxyl-terminal hydrolase 31 1 HS(0.5)S(0.5)PAPAQPK;HS(0.5)S(0.5)PAPAQPK 93.62299999999999 0.0037830999999999997 4500600.0 30223.0 25030.0 32721.0 46132.0 35675.0 35835.0 30946.0 32496.0 34586.0 36847.0 True False 39833.285322547476 33120.45801167237 32287.098160478385 35496.98013229509 30722.142045324545 33594.231785096505 33700.13404965437 27474.489883792576 36414.145351281586 35556.99774535394 1.1202657099403814 0.9314750994689943 0.9080378043080756 0.9983120730977155 0.8640251987905492 0.9447994463898769 0.9477778267727287 0.7726886865014506 1.02410629862696 1.0 15.11784589492235 -4.761713611565772 6.263787279356669 0.9248876665387968 1.1264957426969469 0.39017442611481357 0.06996476033084553 0.12009947031681174 20.18871515394157 0.01632437624959655 0.10370529754645637 1.730957434675917e-05 4.761713611565772 0.20160807615815002 HS(ph)SPAPAQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HSSPAPAQPK 10 0 I3L4X5;Q70CQ4 I3L4X5 USP31 Ubiquitin carboxyl-terminal hydrolase 31 1 HS(0.5)S(0.5)PAPAQPK;HS(0.5)S(0.5)PAPAQPK 91.961 0.0043848 3580900.0 27166.0 30086.0 29704.0 34440.0 38358.0 36425.0 30951.0 34110.0 30753.0 23005.0 True False 31764.667247042587 33072.73924855287 30412.256013047307 32510.43845598652 30842.025255206947 34514.80887745225 28019.09721416504 33214.64864253241 31202.704446039977 27175.624392520214 1.1688661422545072 1.2170001605429817 1.1191005429637135 1.196308794470042 1.1349150551144602 1.2700649809890683 1.0310378451461444 1.222222097376146 1.1481872134878406 1.0 14.730025562829406 -13.9865072494247 0.30659331762622427 1.451713619616006e-13 1.1764384663222547 0.39850982004176194 0.06226371867568713 194.0351039585988 2.432487885137491 123.64218481488356 0.05606191659216231 1.0315558601349667e-14 13.9865072494247 1.1764384663221095 HS(ph)SPAPAQPK ddPTM_PC-9_Lapatinib_30min_R1 2 HSSPAPAQPK 10 0 I3L4X5;Q70CQ4 I3L4X5 USP31 Ubiquitin carboxyl-terminal hydrolase 31 1 HS(0.5)S(0.5)PAPAQPK;HS(0.5)S(0.5)PAPAQPK 93.345 0.0038836999999999995 4638500.0 46667.0 45782.0 43085.0 35522.0 36660.0 39841.0 35546.0 36366.0 36439.0 29189.0 True False 46001.520022320314 45675.994591837676 39542.717612909546 38134.40637791828 34503.73087633311 38137.093303907124 37386.39795208622 38055.697120610006 32334.856100318935 34234.27975810229 1.3437268243224265 1.3342180678133722 1.1550620574557553 1.113924599768831 1.0078707985135003 1.1140030861867671 1.0920749090168287 1.111625463994267 0.9445169090395771 1.0 15.063154039990467 -5.403644641065156 1.6396071133087171 1.0572930083203127 1.3651542558197574 0.8195548126349504 0.053027738971832133 0.1745766561407783 0.8505063088295488 0.015674425342722887 0.057309434993097715 3.947801965545896e-06 5.403644641065156 0.30786124749944466 HS(ph)SPHISR ddPTM_PC-9_AZD4547_30min_R2 1 HSSPHISR 8 0 O60583-2;O60583 O60583-2 CCNT2 Cyclin-T2 1 HS(0.5)S(0.5)PHISR 77.37899999999999 0.013388999999999998 2491800.0 1095.5 1059.3 6446.5 19724.0 10960.0 8896.5 2793.2 8805.9 3584.6 8110.1 True False 1443.8462121844534 1401.69800925947 6361.015197931724 15176.936532762264 9438.393183370905 8340.200448614787 3041.789388854605 7445.150494451291 3774.0746378940617 7826.167867522317 0.1844895530769595 0.17910400504905513 0.8127879832899055 1.9392551743931765 1.2060044383329849 1.065681261863248 0.38866907027099123 0.9513149501108705 0.4822378847195485 1.0 12.934090340344778 -5.3218182961503455 4.512724826317613 1.0115901249881565 0.1756885474271817 0.3958790442537439 0.39833914245080143 0.21339741262941359 8.891731242507978 0.11496992584822423 0.26085674678006926 4.766303617925351e-06 5.3218182961503455 -0.8359015775609748 HS(ph)SPHISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSSPHISR 8 0 O60583-2;O60583 O60583-2 CCNT2 Cyclin-T2 1 HS(0.569)S(0.43)PHIS(0.001)R 58.37 0.044163 786320.0 500.16 602.05 3368.8 2556.8 4446.1 5745.6 1980.2 740.95 3157.5 2257.3 True False 584.8272093897089 661.8175451901634 3449.124968245146 2413.550785257443 3574.918621595904 5444.290621449266 1792.6211205935065 721.5008476014185 3203.6724640968746 2666.5306212230307 0.21932139264970152 0.24819424158220024 1.2934878530152303 0.9051277214099435 1.3406628797520548 2.041713145207456 0.6722672173069976 0.27057662186924186 1.201438467872339 1.0 11.380748180030812 -5.251611844133642 23.565872070611775 1.0859346158902656 0.23375745036263448 0.38065572980131557 0.4371773979674059 353.93412099815936 848702.7340640279 0.12129763537626358 0.3115553570213491 5.602581151557797e-06 5.251611844133642 -0.8521771655276311 HS(ph)SPSGTVAAR ddPTM_PC-9_AZD4547_30min_R2 1 HSSPSGTVAAR 11 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 HS(0.574)S(0.388)PS(0.029)GT(0.009)VAAR 80.737 0.015835 3462800.0 12442.0 12249.0 17168.0 26055.0 18854.0 17290.0 14808.0 17855.0 15263.0 15725.0 True False 16398.297190323123 16208.24970774969 16940.341102628074 20048.422295737215 16236.447543729468 16208.85356674531 16125.883313102893 15095.920017082613 16069.771019967937 15174.472536317486 1.0806502269569254 1.0681260695525354 1.1163710015016526 1.3211940149981998 1.0699843111429626 1.0681658639502765 1.0626981118789052 0.9948233772839965 1.0590003034047943 1.0 13.889358748915779 -6.505750989291716 24.997420605513685 1.0416519020097974 1.1459187067017373 0.3619865189081255 0.06876108001735677 918.9435297913592 1341171.4216098976 0.022922585165291182 0.02541581879996926 3.1206783694201006e-07 6.505750989291716 0.10426680469193994 HS(ph)SPSGTVAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSSPSGTVAAR 11 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 HS(0.5)S(0.5)PSGTVAAR 81.278 0.008633799999999999 889490.0 5027.7 5002.3 4990.5 6199.9 5513.3 4491.0 6078.8 3877.4 4104.3 4481.3 True False 5878.790308398591 5498.895284951007 5109.492446576641 5852.539703346998 4433.008442555202 4255.48405404634 5502.972057299167 3775.6223584448912 4164.317622927251 5293.724216048718 1.1105206974281279 1.0387574154846002 0.9651980794704887 1.1055618812941082 0.8374082709325645 0.8038733943005952 1.0395275297145408 0.7132261153685578 0.7866517886032859 1.0 12.370067322241423 -6.268910810932466 24.89420917669956 0.8549344091416959 1.0474335525678657 0.4740534616015577 0.09847519582939768 483.1673369478066 1609872.2415852381 0.03024641967364959 0.034992235291180625 5.383803358663569e-07 6.268910810932466 0.1924991434261698 HS(ph)SPTEERDEPAYPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSSPTEERDEPAYPR 15 1 F5H4R1;J3KNB8;F5H538;Q9Y6R4-2;Q9Y6R4 F5H4R1 MAP3K4 Mitogen-activated protein kinase kinase kinase 4 1 HS(0.544)S(0.451)PT(0.005)EERDEPAYPR 61.126999999999995 0.022749000000000002 3538100.0 5163.3 7338.8 9640.5 9191.5 8134.6 8859.4 8546.4 7738.7 8754.6 5772.6 True False 6037.344710176512 8067.347563560452 9870.366081799846 8676.53005424506 6540.683524714702 8394.797467917646 7736.8231214222515 7535.567324830421 8882.619462923987 6819.12668412354 0.885354531428901 1.183047028931586 1.447453103456822 1.2723814142426733 0.9591673285587851 1.2310663603687877 1.1345768277681825 1.1050634009153864 1.3026036726381285 1.0 12.735371271835394 HS(ph)SPTEERDEPAYPR ddPTM_PC-9_Lapatinib_30min_R1 1 HSSPTEERDEPAYPR 15 1 F5H4R1;J3KNB8;F5H538;Q9Y6R4-2;Q9Y6R4 F5H4R1 MAP3K4 Mitogen-activated protein kinase kinase kinase 4 1 HS(0.707)S(0.281)PT(0.012)EERDEPAYPR 62.468999999999994 0.020278 7659000.0 15756.0 23543.0 15465.0 16458.0 19731.0 15999.0 21051.0 25582.0 19918.0 15808.0 True False 15531.316550703466 23488.48762997762 14193.527396626354 17668.376222278563 18570.461372638536 15314.760065490585 22140.917776665938 26770.633111682484 17674.62509416156 18540.391737164035 0.8377016392577668 1.266881949581204 0.7655462515484809 0.9529667157389385 1.0016218446676197 0.8260213852327779 1.1941990272128222 1.443908709761564 0.9533037567233786 1.0 14.178384106322671 -7.281217628251573 24.091253242957315 1.184845319197402 0.9517834628967554 0.23031669537400323 0.1789603358372809 680.6200339750119 829036.9346309738 0.07196877035036713 0.048608029061787135 5.233381221737858e-08 7.281217628251573 -0.23306185630064657 HS(ph)TSGTDEGEDGDEPDDGSNDVVDLLPR ddPTM_PC-9_AZD4547_30min_R2 1 HSTSGTDEGEDGDEPDDGSNDVVDLLPR 28 0 Q14008-2;Q14008;Q14008-3 Q14008-2 CKAP5 Cytoskeleton-associated protein 5 1 HS(0.282)T(0.249)S(0.249)GT(0.22)DEGEDGDEPDDGSNDVVDLLPR 51.81100000000001 0.040518 0.0 0.0 0.0 1197.6 2367.0 796.4 980.39 553.59 2166.6 700.44 1256.3 True False 0.0 0.0 1181.719041502061 1821.3247197854523 685.8336068646522 919.08605831703 602.8584375540679 1831.801753515049 737.4638284233993 1212.3173193879595 0.0 0.0 0.9747605042041747 1.5023498309047925 0.5657211984820084 0.7581233424768956 0.4972777571621447 1.5109919855305187 0.6083092410126658 1.0 10.243551652770893 -5.259832741248633 24.99999999672474 0.9316809327609574 2.8336956271791144e-05 0.5500355143099326 0.3354268606971216 99.95883616661912 1555368.6417508412 0.08659760818567185 0.20578359148222783 5.49752557924743e-06 5.259832741248633 -0.9316525958046856 HS(ph)TSGTDEGEDGDEPDDGSNDVVDLLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSTSGTDEGEDGDEPDDGSNDVVDLLPR 28 0 Q14008-2;Q14008;Q14008-3 Q14008-2 CKAP5 Cytoskeleton-associated protein 5 1 HS(0.258)T(0.258)S(0.239)GT(0.244)DEGEDGDEPDDGSNDVVDLLPR 79.515 0.00015900000000000002 0.0 568.28 0.0 720.58 419.99 826.43 772.8 672.38 557.81 0.0 0.0 True False 664.4785799583808 0.0 737.7613600148678 396.4593219259515 664.4969740773937 732.2730075633515 608.6872987903557 543.1680785485491 0.0 0.0 0.0 HS(ph)TSPASSEYSWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HSTSPASSEYSWK 13 0 Q96N46 Q96N46 TTC14 Tetratricopeptide repeat protein 14 1 HS(0.4)T(0.3)S(0.3)PASSEYSWK;HS(0.448)T(0.321)S(0.231)PASSEYSWK 115.1 0.00016694 13352100.0 28340.0 41986.0 71848.0 77801.0 86548.0 83823.0 75057.0 60330.0 68324.0 54196.0 True False 33137.40225948566 46154.09260419266 73561.12880505738 73442.06220424532 69589.54069001635 79427.17431804191 67947.0575943777 58746.40142491878 69323.10924369116 64021.30578470005 0.5175995999038949 0.7209177013572045 1.1490101287911747 1.1471503322851102 1.08697471626152 1.240636587219119 1.0613194586014805 0.917607048229843 1.0828131103233158 1.0 15.966264482079609 -5.09634227605547 3.2940513203622457 1.0895371229802007 0.5421609206975149 0.8349893562794053 0.08489353644738416 0.0970071688707859 1.9244402437791677 0.024046243996890808 0.08796076928391665 8.010464939872295e-06 5.09634227605547 -0.5473762022826858 HS(ph)VTGYGDCAVGAR ddPTM_PC-9_AZD4547_30min_R2 1 HSVTGYGDCAVGAR 14 0 Q96IF1;H0YJL9 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 HS(0.992)VT(0.008)GYGDCAVGAR 68.262 0.032418999999999996 2737900.0 6442.1 7791.5 9118.3 11152.0 10241.0 8162.7 9122.9 9140.2 7760.2 7831.1 True False 8490.553795995862 10309.95000391312 8997.385384208617 8581.078696682454 8819.213922527502 7652.285078616082 9934.82042660092 7727.792110901061 8170.388329237711 7556.9355726013255 1.1235445524743513 1.3643030173888493 1.1906129538578885 1.1355236013648569 1.1670357432320495 1.0126174829861536 1.3146625813009352 1.022609235801771 1.0811774496080846 1.0 12.883585607669135 -6.680977404305591 0.18211904758742337 0.9544727432353914 1.3524318606161436 0.29752384271395327 0.09826424799423465 8.595279163701791 0.7044560973094686 0.40580814302269824 0.9867441766374225 2.084599338871565e-07 6.680977404305591 0.3979591173807522 HS(ph)VTGYGDCAVGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSVTGYGDCAVGAR 14 0 Q96IF1;H0YJL9 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 HS(0.839)VT(0.161)GYGDCAVGAR 111.88 0.0024421 0.0 2987.6 7713.3 6459.2 6771.6 6110.5 7108.0 8215.3 7795.9 7019.3 7814.7 True False 3493.3416722102806 8479.025448576176 6613.211824652412 6392.209205823413 4913.191389591271 6735.243967081139 7437.087310378664 7591.2658854388255 7121.943983289054 9231.443248868842 0.3784177162805319 0.9184940230895249 0.7163789719947367 0.6924387697023074 0.5322235383067865 0.7295981555112122 0.8056256329463927 0.8223270923935981 0.7714875985574334 1.0 13.172340501895404 -8.641799426279507 0.39982852558735077 1.0213110180349463 0.6521171390418642 0.3709780636884724 0.13465770596275908 1.81145287670487 0.7191112267690708 0.2266142039051206 0.10797647788975386 2.2813954639860064e-09 8.641799426279507 -0.3691938789930821 HS(ph)YAGEQPETVPYLLLNR ddPTM_PC-9_AZD4547_30min_R2 4 HSYAGEQPETVPYLLLNR 18 0 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 HS(0.977)Y(0.023)AGEQPETVPYLLLNR;HS(0.962)Y(0.038)AGEQPETVPYLLLNR;HS(0.995)Y(0.005)AGEQPETVPYLLLNR;HS(0.98)Y(0.02)AGEQPETVPYLLLNR 134.58 3.2065e-05 12547800.0 68762.0 62632.0 73132.0 99488.0 89834.0 86482.0 70618.0 80894.0 69017.0 83926.0 True False 90626.88566154928 82876.56916448518 72162.22189640003 76552.57867427758 77362.09974771363 81074.26686866787 76902.86519480693 68393.69105919228 72665.0977190019 80987.77628508632 1.1190193115382274 1.0233219501267707 0.8910260931523873 0.9452362095336915 0.9552318052960252 1.001067946146306 0.9495613871913209 0.8444939989269318 0.897235373684201 1.0 16.305416553921063 -4.964714541320593 3.154931980015675 0.9340647777371217 1.118602011682377 0.6121550762707084 0.046145208404813856 0.18722468167111117 3.536267063864287 0.012814490228579523 0.06916787430061337 1.0846396056836926e-05 4.964714541320593 0.18453723394525523 HS(ph)YAGEQPETVPYLLLNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HSYAGEQPETVPYLLLNR 18 0 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 HS(1)YAGEQPETVPYLLLNR;HS(0.997)Y(0.003)AGEQPETVPYLLLNR;HS(0.991)Y(0.009)AGEQPETVPYLLLNR;HS(0.989)Y(0.011)AGEQPETVPYLLLNR 110.34 0.00012907 10506500.0 101140.0 97712.0 95979.0 98377.0 124643.0 105466.0 111300.0 102237.0 99061.0 87603.0 True False 118261.00439394396 107412.20160388856 98267.50336238454 92865.25563253708 100220.09890726232 99935.17729771796 100756.85825778054 99553.38707905557 100509.57971999997 103484.73043503369 1.1427869976255736 1.0379521805037748 0.9495845710694056 0.8973812391658751 0.968453012207237 0.9656997402187361 0.9736398581144715 0.9620104015399048 0.971250340967922 1.0 16.659058382733114 -4.912291229724439 2.490950837699689 0.9585255933695722 1.1578797853167844 0.8352342577644282 0.0251255885614244 0.15079341480088457 1.473819505921703 0.006983014980832001 0.0575306282812848 1.22379526991817e-05 4.912291229724439 0.19935419194721216 HS(ph)YAGEQPETVPYLLLNR ddPTM_PC-9_Lapatinib_30min_R1 2 HSYAGEQPETVPYLLLNR 18 0 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 HS(0.999)Y(0.001)AGEQPETVPYLLLNR;HS(0.984)Y(0.016)AGEQPETVPYLLLNR 78.67399999999999 0.0024785999999999996 4642000.0 18281.1 20575.2 20399.0 16904.0 16665.4 17985.1 14443.400000000001 16500.0 18939.6 16396.800000000003 True False 18020.408161656847 20527.559388536523 18721.872962417136 18147.17655009094 15685.173937437045 17215.91919831581 15191.208579901037 17266.650236211455 16806.422805170296 19230.965032637356 0.9370516836297065 1.0674222200341317 0.9735274818837106 0.943643572711661 0.815620740343365 0.8952186834669107 0.7899348032779246 0.8978566705782984 0.8739250878282859 1.0 14.231143540192278 -5.945075700252945 2.8769894702998933 0.8701555336319733 1.0014302395542665 0.40655733455989973 0.06108861736744433 0.2185160928865759 3.6778209352376994 0.017270976937667822 0.026754590665347234 1.1348129934074558e-06 5.945075700252945 0.13127470592229318 HS(ph)YPPALGSPGALAGAGVGAAGPLER ddPTM_PC-9_AZD4547_30min_R2 1 HSYPPALGSPGALAGAGVGAAGPLER 26 0 Q96IF1;H0YJL9 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 HS(0.875)Y(0.125)PPALGSPGALAGAGVGAAGPLER 111.8 1.2869e-10 43282000.0 8274.3 6660.5 7731.2 5022.6 9545.2 8153.4 7508.1 9328.4 6923.1 8100.0 True False 10905.355283868395 8813.376371823564 7628.67923652366 3864.7171683964575 8220.013742145247 7643.56660908625 8176.306354883026 7886.9101253068275 7289.040932211228 7816.421465448119 1.395185166520852 1.1275462065066995 0.9759810509509551 0.4944356167947363 1.051633893909275 0.9778856786157245 1.0460421550994594 1.0090180218876756 0.9325291585710755 1.0 12.932292544921115 -4.922786933172386 2.3970106347438853 0.9313648422944992 1.4307567678726378 0.46756228165804603 0.1528002316212799 0.38045421539764573 3.4100011832776573 0.04267919101856758 0.35283244812382886 1.1945740241182118e-05 4.922786933172386 0.4993919255781386 HS(ph)YPPALGSPGALAGAGVGAAGPLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HSYPPALGSPGALAGAGVGAAGPLER 26 0 Q96IF1;H0YJL9 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 HS(0.536)Y(0.456)PPALGS(0.008)PGALAGAGVGAAGPLER;HS(0.974)Y(0.026)PPALGSPGALAGAGVGAAGPLER;HS(0.998)Y(0.002)PPALGSPGALAGAGVGAAGPLER;HS(0.858)Y(0.142)PPALGSPGALAGAGVGAAGPLER 155.37 6.8512e-12 76476400.0 67199.8 80700.8 79033.0 73622.0 83616.0 57473.1 87636.0 73108.9 64730.5 61223.0 True False 78575.39888345027 88712.24209099312 80917.44645432156 69497.19802574428 67232.04504247852 54459.10946038987 79334.48365030429 71189.8688402826 65677.0611044253 72322.24525899865 1.0864623823839812 1.2266245575382653 1.1188458843408688 0.9609380596089435 0.9296177794495839 0.7530063435580884 1.0969582507594113 0.9843426263294119 0.9081170097695975 1.0 16.142151846762467 -5.729351779040207 3.734691637790728 0.9425670745763681 1.1598744017665412 0.5182720253565336 0.08727350109302705 0.17361764878793298 5.0974629339439845 0.02516858330310908 0.04373830698054855 1.8648685331963022e-06 5.729351779040207 0.2173073271901731 HS(ph)YPPALGSPGALAGAGVGAAGPLER ddPTM_PC-9_Lapatinib_30min_R1 2 HSYPPALGSPGALAGAGVGAAGPLER 26 0 Q96IF1;H0YJL9 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 HS(0.933)Y(0.065)PPALGS(0.001)PGALAGAGVGAAGPLER;HS(0.946)Y(0.054)PPALGSPGALAGAGVGAAGPLER 140.73 1.3372e-09 82420000.0 21916.0 31796.0 36494.0 26969.0 35997.0 30166.0 32458.0 37099.0 33870.0 31101.0 True False 21603.473821097832 31722.378315540398 33493.604190913815 28952.390225946685 33879.72723282496 28875.870500380577 34138.516421786284 38822.75497655806 30055.20393308824 36476.766410522454 0.5922529858585787 0.8696598256140775 0.9182174706487117 0.79372140337513 0.9288029221540777 0.7916236372325688 0.9358975529129782 1.0643145979452515 0.8239547221603013 1.0 15.154690222805602 -4.759884700282708 3.99960127664403 0.9027025900684547 0.5571902321295528 0.563802091467895 0.08248373433458767 0.18957576873802748 5.64888449717901 0.020626625022323274 0.19676038433290102 1.7382622542395727e-05 4.759884700282708 -0.3455123579389019 HSADGIPPT(ph)VLRSPVGLSSDGISSSSSSSR ddPTM_PC-9_AZD4547_30min_R2 1 HSADGIPPTVLRSPVGLSSDGISSSSSSSR 30 1 O60583-2;O60583 O60583-2 CCNT2 Cyclin-T2 1 HSADGIPPT(0.394)VLRS(0.394)PVGLS(0.064)S(0.064)DGIS(0.012)S(0.014)S(0.015)S(0.017)S(0.019)S(0.003)S(0.003)R 58.688 0.00084237 7749100.0 12519.0 11367.0 16082.0 25391.0 26870.0 17785.0 15430.0 25357.0 19578.0 17348.0 True False 16499.78158862362 15041.160456199765 15868.742172207876 19537.49723703947 23139.564309961344 16672.90113849425 16803.24010812924 21438.658295892674 20612.85311072084 16740.65180032024 0.9856116586994532 0.8984811723944963 0.9479166260362882 1.1670690884727517 1.382237955007146 0.9959529256904625 1.0037387019666584 1.2806346223318834 1.231305289458713 1.0 14.031068080124868 -5.754189012499253 8.954304798012785 1.1603206743893908 0.9390353033557791 0.374768090670622 0.12244523045169001 0.13992654618742467 102.74457446893287 0.03510604433778765 0.05751677205050444 1.761209370690135e-06 5.754189012499253 -0.22128537103361168 HSADGIPPT(ph)VLRSPVGLSSDGISSSSSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSADGIPPTVLRSPVGLSSDGISSSSSSSR 30 1 O60583-2;O60583 O60583-2 CCNT2 Cyclin-T2 1 HS(0.001)ADGIPPT(0.453)VLRS(0.453)PVGLS(0.034)S(0.034)DGIS(0.009)S(0.01)S(0.003)S(0.001)S(0.002)SSR 54.31100000000001 0.0014304 6632000.0 5053.4 6219.1 7323.8 8807.3 9522.4 7811.3 8786.0 10826.0 8575.4 6912.7 True False 5908.840810800453 6836.491147399962 7498.427167666168 8313.855534651851 7656.554077120357 7401.6616769922475 7953.726474868474 10541.82897109516 8700.79900193708 8165.917789096912 0.7235978812681539 0.8371981354659248 0.9182589589229059 1.0181164872554147 0.9376232133200441 0.9064090367006762 0.974015007288984 1.2909545801661817 1.0655016651715914 1.0 12.995399327873054 -3.5413947773381818 0.32916936366398203 1.0990727943566798 9.656055616460745e-12 0.5553613277445535 0.09463169626087989 12.56530719741451 0.5779779752316992 0.09839141990206614 6.452107574724384 0.0002874784023798092 3.5413947773381818 -1.0990727943470238 HSADGIPPTVLRS(ph)PVGLSSDGISSSSSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSADGIPPTVLRSPVGLSSDGISSSSSSSR 30 1 O60583-2;O60583 O60583-2 CCNT2 Cyclin-T2 1 HSADGIPPT(0.464)VLRS(0.529)PVGLS(0.003)S(0.003)DGISSSSSSSR 70.718 2.6933e-05 4947800.0 13761.0 14210.0 15764.0 21219.0 21421.0 22597.0 19779.0 18859.0 17672.0 18197.0 True False 16090.465507861047 15620.67488938164 16139.873545302915 20030.16822292619 17223.708821935143 21411.973540254985 17905.389932440637 18363.971232762196 17930.419567860645 21495.972052627254 0.7485339796901372 0.7266791588274544 0.7508324585549639 0.9318103025947174 0.8012528477320032 0.9960923603656248 0.8329648870311137 0.8542982465646506 0.8341292742641604 1.0 14.391778730335725 -5.716489146068315 8.697468383208975 0.8847926187104485 0.7397990969770649 0.5336249356953007 0.06433767858805138 0.22540220965383845 39.79999879982097 0.016631290721671653 0.028704583714487673 1.9209269691535107e-06 5.716489146068315 -0.14499352173338353 HSAGS(ph)GAEESNSSSTVQK ddPTM_PC-9_AZD4547_30min_R2 1 HSAGSGAEESNSSSTVQK 18 0 Q8IYL3 Q8IYL3 C1orf174 UPF0688 protein C1orf174 1 HS(0.065)AGS(0.935)GAEESNSSSTVQK 112.56 9.9613e-05 5564200.0 49473.0 58309.0 123280.0 168450.0 135820.0 116560.0 94798.0 141110.0 110930.0 113620.0 True False 65204.38489767366 77156.24395535774 121645.22665027896 129616.45502655653 116963.73742385389 109271.48477384823 103234.83835194031 119304.69188521561 116793.53333191642 109642.19838323636 0.5947015461124047 0.703709384644685 1.1094745311936192 1.1821767251829758 1.0667766530458125 0.9966188783620303 0.9415611860599495 1.088127506055703 1.0652242936946934 1.0 16.742443634790817 -5.17548285629748 4.321620335097333 1.0580362342858607 0.62283758853959 0.8633714838964399 0.06516478760385579 0.08003462410639364 2.6685006577795876 0.01878453778569772 0.05485692034337376 6.676012538927475e-06 5.17548285629748 -0.43519864574627065 HSAGS(ph)GAEESNSSSTVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HSAGSGAEESNSSSTVQK 18 0 Q8IYL3 Q8IYL3 C1orf174 UPF0688 protein C1orf174 1 HS(0.179)AGS(0.821)GAEESNSSSTVQK;HS(0.196)AGS(0.804)GAEESNSSSTVQK 132.65 2.2684e-05 12347100.0 87770.0 114148.0 151982.0 168781.0 200660.0 177530.0 159798.0 158357.0 152840.0 121639.0 True False 102627.72746348131 125479.85906214909 155605.82727494472 159324.74776538508 161342.11344986255 168220.01427629628 144660.77660266685 154200.2965431104 155074.99585512755 143691.1878062061 0.714224226484185 0.8732606430352687 1.082918372731442 1.1087997127580553 1.1228393049924674 1.1707051548851541 1.006747726226388 1.0731367657081223 1.0792241209967213 1.0 17.132612062341217 -5.037510858486369 2.2969930358958788 1.0879236245442065 0.7023830797225263 0.8568928377918772 0.048881885469511645 0.12826035986005044 1.1441749634539227 0.01355005215723069 0.0801781727447665 9.172530014034141e-06 5.037510858486369 -0.3855405448216802 HSAGS(ph)GAEESNSSSTVQK ddPTM_PC-9_Lapatinib_30min_R1 1 HSAGSGAEESNSSSTVQK 18 0 Q8IYL3 Q8IYL3 C1orf174 UPF0688 protein C1orf174 1 HSAGS(0.999)GAEES(0.001)NSSSTVQK 204.78 4.1951e-20 2646900.0 16781.0 15750.0 23671.0 15924.0 20417.0 20099.0 18785.0 18933.0 25318.0 17446.0 True False 16541.699862741494 15713.531842677108 21724.86175270239 17095.104080906764 19216.112201366428 19239.412623057386 19757.595384289074 19812.696298314622 22466.42022964063 20461.51785466623 0.8084297548321507 0.7679553371498123 1.0617424331376304 0.8354758528829396 0.9391342488790104 0.9402729924393101 0.9655977393575118 0.968290643882822 1.097984049336652 1.0 14.320625549079269 -2.4404372656183813 0.2623376149651955 1.0272118506576737 5.347654417754788e-19 0.46815037218353805 0.07388769300951342 28.800173554781885 0.6100784836640415 0.08994191670781114 12.036859535599085 0.00362712676761109 2.4404372656183813 -1.0272118506576737 HSAIS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 HSAISPK 7 0 A0A0C4DGZ1;Q8N5P1 A0A0C4DGZ1 ZC3H8 Zinc finger CCCH domain-containing protein 8 1 HSAIS(1)PK;HSAIS(1)PK;HSAIS(1)PK 79.148 0.015466999999999998 46450400.0 296942.0 198710.0 200130.0 241851.0 238590.0 243386.0 281234.0 185412.0 322578.0 360651.0 True False 391363.3792227071 262939.12151416 197476.1454373812 186095.98851070207 205465.89686318123 228167.03494481617 306263.28117755166 156760.83574389934 339628.81452396075 348024.71826362144 1.1245275369385044 0.7555185241612326 0.5674198844916445 0.5347206067407495 0.590377309658635 0.655605831916756 0.880004393669428 0.45043017785063266 0.9758755533757778 1.0 18.4088302507692 -8.392175718270193 8.655946762698704 0.998707305374052 0.6888269215360782 0.28962632412457046 0.18357900255383294 0.39539635023619124 24.99679690608443 0.1786676386155925 0.0461689685772754 4.0534449734026124e-09 8.392175718270193 -0.3098803838379738 HSAIS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HSAISPK 7 0 A0A0C4DGZ1;Q8N5P1 A0A0C4DGZ1 ZC3H8 Zinc finger CCCH domain-containing protein 8 1 HSAIS(1)PK;HSAIS(1)PK;HSAIS(1)PK;HSAIS(1)PK 82.645 0.012568000000000001 54738700.0 230990.0 306055.0 244591.0 289806.0 409372.0 344172.0 274518.0 384543.0 353010.0 315395.0 True False 270092.04473954084 336438.1177529693 250422.9770565333 273569.10938372917 329158.49530148995 326123.01443982124 248513.6677017913 374449.15370698745 358172.10342069215 372573.6168345543 0.7249360462887483 0.9030111165986523 0.6721436133459138 0.7342686036333345 0.8834723674157976 0.8753250356550072 0.6670189634284993 1.0050340034497558 0.9613458582059038 1.0 18.50716599034385 -7.780843653836097 24.9998992964123 0.9873925841004574 0.7864903040257714 0.5806435625519031 0.08117109620997569 187.04363730812761 240978.11759371264 0.04436691451281486 0.02136324242288973 1.6563661485368285e-08 7.780843653836097 -0.20090228007468602 HSAIS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 HSAISPK 7 0 A0A0C4DGZ1;Q8N5P1 A0A0C4DGZ1 ZC3H8 Zinc finger CCCH domain-containing protein 8 1 HSAIS(1)PK;HSAIS(1)PK;HSAIS(1)PK;HSAIS(1)PK 83.78299999999999 0.011625 68862400.0 438324.0 420259.0 328526.0 389059.0 435743.0 309777.0 404989.0 418497.0 380008.0 366421.0 True False 432073.4193812233 419285.9161061366 301515.8604270337 417671.6967227767 410113.45344369946 296528.55983545684 425957.34879360395 437941.89841841074 337207.4973783583 429756.38162470714 1.0053915144849195 0.9756362768157469 0.7015971683472012 0.9718801501998785 0.9542928761016951 0.6899922200443459 0.9911600316050204 1.0190468766577891 0.7846480280375013 1.0 18.713159537455937 -10.62454871946659 5.203946223138383 1.0000018802354727 0.8995453244197829 0.059528516859752245 0.12008085223954797 2.9236457012697287e-06 5.048196916560619e-07 0.11488753267006632 0.027863730587936272 2.3738391088231177e-11 10.62454871946659 -0.1004565558156898 HSAS(ph)PVVFTSAR ddPTM_PC-9_AZD4547_30min_R2 4 HSASPVVFTSAR 12 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 HS(0.067)AS(0.933)PVVFTSAR;HS(0.163)AS(0.837)PVVFTSAR;HS(0.004)AS(0.996)PVVFTSAR;HSAS(1)PVVFTSAR 133.87 3.1552e-05 67666000.0 71688.0 92058.0 118027.0 166810.0 158530.0 121383.0 102004.0 131170.0 110200.0 111858.0 True False 94483.29279696879 121813.94820769229 116461.88486252818 128354.53168880925 136520.84592698785 113792.90182141389 111082.15839206832 110900.69048673924 116024.94702224102 107941.88546692515 0.8753163092182575 1.128514178539319 1.0789313560602356 1.189107741944519 1.264762472291812 1.0542052450647768 1.029092255629585 1.0274110926172464 1.0748834571524382 1.0 16.719895267249342 -6.97863361234273 24.997472839390312 1.0360619905676673 1.1162708505971295 0.11990414145156947 0.09480991038395509 502.97837556866796 588454.7930065205 0.034683150336232364 0.03058483476249067 1.0504282369217371e-07 6.97863361234273 0.08020886002946215 HSAS(ph)PVVFTSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 HSASPVVFTSAR 12 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 HS(0.078)AS(0.922)PVVFTSAR;HS(0.32)AS(0.68)PVVFTSAR;HS(0.004)AS(0.996)PVVFTSAR;HS(0.029)AS(0.971)PVVFTSAR;HS(0.005)AS(0.995)PVVFTSAR;HS(0.043)AS(0.957)PVVFTSAR 125.33 0.00016783 63661300.0 103339.0 118952.0 145024.0 148742.0 185667.0 146284.0 151777.0 140344.0 140794.0 119573.0 True False 120832.25166171454 130760.76843361881 148481.9221665827 140408.4679680707 149286.88417171183 138612.60952173575 137399.5837896782 136660.11870675953 142852.84589392098 141250.63836065272 0.8554457032130058 0.9257357697722377 1.0511946982318512 0.994037758679492 1.0568935185308 0.9813237740407138 0.9727360200586018 0.9675008926885533 1.0113430109191959 1.0 17.107897862018916 -5.003720814488151 3.8807443317244825 1.0026293828513257 0.8629565906344997 0.7341444920956546 0.028802161660529246 0.10887072538559148 3.6666388403478214 0.007754279915154392 0.03157821190286887 9.914691043975354e-06 5.003720814488151 -0.13967279221682605 HSAS(ph)PVVFTSAR ddPTM_PC-9_Lapatinib_30min_R1 4 HSASPVVFTSAR 12 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 HS(0.415)AS(0.585)PVVFTSAR;HS(0.003)AS(0.997)PVVFTSAR;HS(0.012)AS(0.988)PVVFTSAR;HS(0.091)AS(0.909)PVVFTSAR 126.07 0.00015557 62246000.0 153473.0 133622.0 158655.0 110836.0 136411.0 132501.0 122528.0 112602.0 142296.0 110060.0 True False 151284.44687649858 133312.60646871125 145610.9983260106 118987.24917805735 128387.57317434467 126834.2411049169 128871.90030589144 117833.8999938109 126269.12603669098 129083.72435426859 1.171987000168204 1.032760769303778 1.1280353046398253 0.9217835151044945 0.9946069794359718 0.9825734556342827 0.9983590181532429 0.9128486227312229 0.9781955600393666 1.0 16.97794758295472 -5.755642608224287 24.999971841502813 0.9688953943490324 1.103111024625836 0.6931003268857046 0.04294803557648732 78.08026880696552 336735.00416882144 0.011203480587582805 0.018754201600488688 1.7553244079418058e-06 5.755642608224287 0.1342156302768036 HSCS(ph)GSSPPR ddPTM_PC-9_Lapatinib_30min_R1 1 HSCSGSSPPR 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 HS(0.004)CS(0.363)GS(0.363)S(0.27)PPR 78.655 0.020097999999999998 1214600.0 2844.3 2349.9 2301.7 2533.9 2135.5 2545.3 2877.2 2956.4 3745.1 2889.5 True False 2803.7397604192615 2344.4589509274247 2112.463110818938 2720.251458842608 2009.8940885545385 2436.4434523840982 3026.1673377522798 3093.7651368688175 3323.287400348651 3388.946224983268 0.8273190467733386 0.6917958549014744 0.6233392242242992 0.8026835713086709 0.593073467421119 0.7189383633244659 0.8929523034161513 0.9128988574860293 0.98062559265456 1.0 11.726621029313597 -7.380279203077542 2.50880383208815 0.9586975275502299 0.7019067147057011 0.7414118702109095 0.06951649108311954 0.15209400900406378 1.8643457949750406 0.03454779191164129 0.020988484017576973 4.166014689230504e-08 7.380279203077542 -0.25679081284452876 HSCSGS(ph)SPPR ddPTM_PC-9_AZD4547_30min_R2 2 HSCSGSSPPR 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 HSCS(0.002)GS(0.499)S(0.499)PPR;HSCS(0.001)GS(0.5)S(0.5)PPR 92.906 0.007008499999999999 1886600.0 415.8 607.17 403.17 1041.4 758.69 797.3 479.04 0.0 421.08 687.92 True False 548.015750822726 803.4258286435123 397.82370237340166 801.3213194696118 653.3589894426709 747.4447049604419 521.6736319765542 0.0 443.3374291481423 663.8361301865517 0.8255286597141409 1.2102773442261014 0.5992799793250255 1.207107120313599 0.984217278530868 1.125947611122634 0.7858470008704606 0.0 0.6678416690329213 1.0 9.374683341972583 -7.529928378935294 24.992715867476623 0.4789371097727364 0.9904062910165202 0.3058539597483113 0.288175108396 171.4677996327491 607885.481423371 0.12589913535763878 0.07288957293092656 2.9516959613257957e-08 7.529928378935294 0.5114691812437838 HSCSGS(ph)SPPR ddPTM_PC-9_Lapatinib_30min_R1 1 HSCSGSSPPR 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 HSCSGS(0.637)S(0.363)PPR 76.32600000000001 0.021317 0.0 2285.0 3518.7 5975.3 2615.4 4198.9 3435.3 2439.2 2532.5 4677.5 3312.7 True False 2252.41548098232 3510.5526663382843 5484.033899325019 2807.745240718638 3951.928957355022 3288.3802270754272 2565.4898409027383 2650.1691953457876 4150.67069374137 3885.295781104713 0.5797281874745419 0.9035483690613956 1.4114842751471894 0.7226593286342556 1.017150091010925 0.846365479577577 0.6603074734694427 0.6821023017692259 1.068302370678508 1.0 11.923808717449443 -6.941520204719506 8.79487146973538 0.8158856130717721 0.940598029373782 0.014296538245706536 0.23375452790892084 0.9941562661191732 137.65867583543425 0.08364349793931555 0.073716201741229 1.1441416495784844e-07 6.941520204719506 0.12471241630200991 HSCSGSS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 4 HSCSGSSPPR 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 HS(0.001)CS(0.004)GS(0.115)S(0.881)PPR;HS(0.001)CS(0.054)GS(0.054)S(0.891)PPR;HSCSGS(0.001)S(0.999)PPR;HSCSGS(0.001)S(0.999)PPR 155.53 0.00011049 1034167100.0 96291.4 78178.2 155419.5 228999.0 178835.3 161400.4 122167.7 144585.2 170571.1 192164.5 True False 126910.06221445759 103447.77429197461 153358.53588070266 176206.81854928113 154007.10551697924 151308.0074733439 133040.38862980585 122242.8795773671 179587.14011819765 185436.87934532194 0.6843841562827679 0.5578597669308993 0.827012061581975 0.9502253228773737 0.8305095839656903 0.8159542374069885 0.7174429870665427 0.6592155778771789 0.9684542834856984 1.0 17.500568667470027 -14.52287874514093 0.031632908472598954 2.1712157691726675 3.4957259770886114e-15 0.32648011948928746 0.11356364463663696 1935.441307172259 4.586820003832692 251.7195266479837 96.85280281476935 3.0000000009629884e-15 14.52287874514093 -2.171215769172664 HSCSGSS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 HSCSGSSPPR 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 HSCSGS(0.149)S(0.851)PPR;HS(0.001)CS(0.006)GS(0.207)S(0.785)PPR;HS(0.007)CS(0.007)GS(0.039)S(0.947)PPR;HS(0.001)CS(0.009)GS(0.226)S(0.764)PPR;HS(0.001)CS(0.004)GS(0.17)S(0.825)PPR;HSCS(0.001)GS(0.037)S(0.962)PPR;HS(0.005)CS(0.019)GS(0.106)S(0.87)PPR 116.71 0.00057662 989553000.0 52718.76 87585.87999999999 115152.75 109285.00000000001 159282.33000000002 139465.86 103150.61 107083.8 130634.27 99401.68000000001 True False 61643.00482502762 96280.82733148454 117898.42827923634 103162.11575675031 128072.10085427297 132152.02478598515 93379.43747505493 104272.96371466447 132544.54906299183 117422.41772073391 0.5249679407183845 0.8199526904689488 1.0040538303310576 0.8785555412604523 1.0906954850722563 1.1254411836441889 0.7952436961155027 0.888015812812313 1.1287840229812245 1.0 16.841348341547906 -4.7397352300796936 1.7868112212097107 0.984980629285392 0.33525088254677005 0.6485195927072317 0.10479557311386882 0.6498449836954533 1.9569595938921776 0.0297107673435976 0.7471006746098344 1.8208105870726488e-05 4.7397352300796936 -0.6497297467386219 HSCSGSS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 6 HSCSGSSPPR 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 HSCS(0.001)GS(0.093)S(0.906)PPR;HS(0.001)CS(0.011)GS(0.083)S(0.904)PPR;HSCS(0.009)GS(0.009)S(0.982)PPR;HSCS(0.001)GS(0.026)S(0.972)PPR;HSCSGS(0.026)S(0.974)PPR;HS(0.002)CS(0.032)GS(0.157)S(0.809)PPR 133.91 0.00011049 1016835040.0 113346.70000000001 127260.29999999999 175122.6 113322.1 173784.55 144916.34 135809.40000000002 142491.30000000002 204317.4 120685.70000000001 True False 111730.3552727609 126965.63659419981 160724.69582078457 121656.18526544356 163562.88444257088 138718.60595468813 142840.94621150245 149111.9659880652 181305.02285439527 141546.06244141335 0.789356859142632 0.8969916534891357 1.1354939377936377 0.8594812400083378 1.1555452806062367 0.9800244779829498 1.0091481440582288 1.0534518828440278 1.2808906141733074 1.0 17.11091209104 -3.858635633976666 0.6880772178420601 1.0694965056824057 4.989330270864612e-17 0.3885868496692637 0.10973415125496475 10.140148101877084 1.4161578257691885 0.04396968679091943 11.339699070880902 0.00013847276557916929 3.858635633976666 -1.0694965056824057 HSCSGSSPPR ddPTM_PC-9_Lapatinib_30min_R1 1 HSCSGSSPPR 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 68.786 0.033641000000000004 679180.0 1093.0 707.19 6300.5 1247.3 2006.1 2093.2 886.98 518.17 4160.8 920.76 False True 1077.4136195683488 705.5525450046244 5782.497210633323 1339.0306028708246 1888.1051421443487 2003.6787154875226 932.903484373529 542.2460698725872 3692.1668888335853 1079.9121391644203 0.9976863677095021 0.653342544654183 5.354599694663603 1.23994402350815 1.748387737918444 1.8554090122904487 0.8638698006444867 0.502120543150991 3.4189511858718356 1.0 10.076698225247089 HSDGNLCVK ddPTM_PC-9_Lapatinib_30min_R1 1 HSDGNLCVK 9 0 P49458;Q6P2S0;Q659G3;E9PE20;P49458-2 P49458 SRP9;DKFZp564M2223 Signal recognition particle 9 kDa protein 0 95.35799999999999 0.0045756 3552200.0 46112.0 47147.0 43032.0 41008.0 43354.0 45745.0 34066.0 41647.0 38428.0 41383.0 False True 45454.434424094885 47037.834018203044 39494.07506832366 44023.86511867779 40804.00295724347 43788.59298680334 35829.77079378184 43582.07165984836 34099.83397522042 48535.99641061862 0.9365097615292892 0.9691329630952459 0.8137068977465808 0.9070353629135823 0.8406956892784927 0.9021879888144905 0.7382102654421464 0.8979329751704356 0.702567918596601 1.0 15.566767489341329 -5.029821544758402 0.8364276868114656 0.8384329930611137 1.001490408885776 0.14286447689262383 0.08473223511148242 3.0321184495249214 2.1035289833396034 0.030400623076417332 0.42635159814808404 9.336378616077704e-06 5.029821544758402 0.16305741582466216 HSEEAEFTPPLKCS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 HSEEAEFTPPLKCSPK 16 1 Q3B726 Q3B726 TWISTNB DNA-directed RNA polymerase I subunit RPA43 1 HSEEAEFTPPLKCS(1)PK;HSEEAEFT(0.001)PPLKCS(0.999)PK 97.631 0.00091086 37544000.0 176590.0 146723.0 140751.0 151160.0 162616.0 146269.0 164066.0 140289.0 141694.0 174954.0 True False 232741.94669982008 194148.34042535376 138884.54977493046 116312.39739871939 140039.57535648195 137122.77630736117 178667.55616204333 118610.55857051231 149183.6555659657 168828.91371185306 1.3785668673853455 1.1499709152705582 0.8226348598793343 0.6889364791935718 0.8294762566291991 0.8121996007235703 1.0582758144554685 0.7025488464194564 0.8836380705533845 1.0 17.365202476210285 -5.051094228581334 2.748515827518689 0.8384487692205621 1.3719220049481735 0.7112914315068153 0.10990570678086684 0.15137996033976897 2.089068794545586 0.028990689011574283 0.13731364315632996 8.89008209418457e-06 5.051094228581334 0.5334732357276114 HSEEAEFTPPLKCS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HSEEAEFTPPLKCSPK 16 1 Q3B726 Q3B726 TWISTNB DNA-directed RNA polymerase I subunit RPA43 1 HSEEAEFTPPLKCS(1)PK;HSEEAEFTPPLKCS(1)PK;HSEEAEFT(0.001)PPLKCS(0.999)PK 83.87700000000001 0.0021668000000000004 30740200.0 338762.0 306715.0 255422.0 363051.0 303630.0 230312.0 249429.0 234218.0 218582.0 189746.0 True False 396107.7157455151 337163.638191182 261512.22917332934 342710.429497223 244135.8811261919 218234.03327889592 225801.2794104217 228070.0256744844 221778.34823348324 224145.44777149078 1.7671905438353332 1.5042180938464103 1.1667077416621585 1.5289644866961807 1.0891850963445875 0.9736268813336715 1.007387308800574 1.017509068071704 0.9894394485297746 1.0 17.774075674052114 -2.7491964655922425 0.34773909969365685 0.9472110754985432 5.012165889144372 0.8108966844536201 0.11842632644040267 11.127949060192954 0.34436900461184394 0.10643443454572417 25.334347323148062 0.0017815726395312827 2.7491964655922425 4.064954813645828 HSEEAEFTPPLKCS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 HSEEAEFTPPLKCSPK 16 1 Q3B726 Q3B726 TWISTNB DNA-directed RNA polymerase I subunit RPA43 1 HSEEAEFTPPLKCS(1)PK;HSEEAEFTPPLKCS(1)PK 97.631 0.00091086 50685000.0 415200.0 453740.0 384030.0 471700.0 416580.0 314790.0 272430.0 261120.0 282550.0 252180.0 True False 409279.17186164507 452689.3929077035 352456.53579866973 506390.3915450722 392077.5834277914 301327.16551133076 286535.09238977236 273252.5884654267 250726.24361659525 295768.97699127154 1.383779921833125 1.5305506260755093 1.1916616116539873 1.7121146264099778 1.3256210553798617 1.0187923310165936 0.9687800772906223 0.9238717029930109 0.8477097434867026 1.0 18.174111211498484 -6.744121491466403 3.1160956759227316 0.9365458604439992 1.4490301610670986 0.782994212509601 0.1273079810883233 0.11015270575480599 2.2087988683505726 0.04467320696982951 0.042003744134135844 1.802513427215062e-07 6.744121491466403 0.5124843006230994 HSEITPYATDLAQT(ph)SEKLIPHLHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSEITPYATDLAQTSEKLIPHLHK 24 1 A0A087WUB1;Q6ZRS4-2;Q6ZRS4-3;Q6ZRS4;Q6ZRS4-4 A0A087WUB1 CCDC129 Coiled-coil domain-containing protein 129 1 HSEITPYATDLAQT(0.5)S(0.5)EKLIPHLHK 49.528 0.022902000000000002 5918900.0 27230.0 14798.0 15459.0 24439.0 24722.0 17016.0 21247.0 21473.0 19428.0 26800.0 True False 31839.501182984972 16267.047643425034 15827.601188583983 23069.762062307036 19877.901568361915 16123.651005043988 19234.330345041013 20909.356502524144 19712.097745835028 31658.627851316734 1.0057132397688775 0.5138266800387705 0.49994589983234816 0.7287037887634643 0.6278826000203657 0.5092972153047176 0.6075541377021817 0.6604631319059044 0.6226453603236367 1.0 14.950311107071295 -10.791082181682459 2.831555497451387 1.0031103578734553 0.6316402733938181 0.36764611666183866 0.14037418384246508 6534117.8244076595 8040205.833646417 175172.33879605637 0.035024904317731594 1.617773876813067e-11 10.791082181682459 -0.37147008447963714 HSFAT(ph)EGAGAVENFAAAR ddPTM_PC-9_Lapatinib_30min_R1 1 HSFATEGAGAVENFAAAR 18 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 HS(0.446)FAT(0.554)EGAGAVENFAAAR 72.207 0.017328 2428900.0 14910.0 10418.0 8784.1 10423.0 8588.3 8673.5 8370.8 7635.9 8249.1 8341.2 True False 14697.380665840872 10393.877761080012 8061.905205606563 11189.542190108723 8083.153079247448 8302.554623916025 8804.19906536104 7990.691790223455 7319.999491126019 9782.965306049633 1.502344146794862 1.0624465523405873 0.824075825007905 1.1437781735962291 0.8262477506946644 0.8486746466106605 0.8999519869416954 0.8167964967924538 0.7482393387002452 1.0 13.256056110157765 -1.9029322769647616 0.9531425438907615 0.8719961055114741 199.99997816207048 0.7481228070978436 0.10731115949841895 262.8652063866746 1.0296447943522573 0.034768979052348124 113350.91169642996 0.012504540083764898 1.9029322769647616 199.127982056559 HSGNITFDEIVNIAR ddPTM_PC-9_AZD4547_30min_R2 2 HSGNITFDEIVNIAR 15 0 P30050;P30050-2 P30050 RPL12 60S ribosomal protein L12 0 ; 101.72 0.0033092 0.0 14597.099999999999 12822.7 19305.6 27389.0 19286.7 14193.099999999999 12599.099999999999 19744.1 12825.900000000001 15568.0 False True 19238.674161458406 16967.387013434734 19049.595129945053 21074.889205831754 16609.07461767514 13305.603213312494 13720.395492309206 16693.103019282047 13503.850889406192 15022.969058530416 1.2806173058403663 1.1294296718131247 1.2680313096383713 1.4028444792585728 1.1055787010520464 0.8856839923901222 0.913294531783544 1.1111720295931307 0.8988802970168117 1.0 13.874882347042877 -6.517174028257732 5.92598179136824 0.9676897721588196 1.2602805709910279 0.7397929311859921 0.08609014866545789 0.0860614269048352 11.904010235001559 0.028722942855966827 0.030446950971361263 3.0396667419309174e-07 6.517174028257732 0.2925907988322083 HSGNITFDEIVNIAR ddPTM_PC-9_Lapatinib_30min_R1 1 HSGNITFDEIVNIAR 15 0 P30050;P30050-2 P30050 RPL12 60S ribosomal protein L12 0 132.84 4.6704e-06 2133800.0 8231.8 6820.7 7416.1 8411.9 7750.0 5808.6 7127.3 7693.5 6138.8 5693.3 False True 8114.413022472759 6804.907088212557 6806.376884973854 9030.53918727579 7294.160237086239 5560.179718507945 7496.316719853263 8050.968096502586 5447.383699570182 6677.379319154601 1.2152092362337288 1.0190984760581343 1.019318591868701 1.35240769703931 1.092368710605125 0.8326889117348959 1.1226435344700987 1.2057077652317483 0.8157966530288197 1.0 12.705066281807685 -6.531008514963628 24.984368086875364 1.0102177493415974 1.1438309810964917 0.21117655989008222 0.14139907756918146 357.5314427951452 1098754.5117021357 0.04731944234949432 0.04739960414841047 2.944363904772994e-07 6.531008514963628 0.13361323175489437 HSGPNS(ph)ADSANDGFVR ddPTM_PC-9_Lapatinib_30min_R1 1 HSGPNSADSANDGFVR 16 0 P52597 P52597 HNRNPF Heterogeneous nuclear ribonucleoprotein F;Heterogeneous nuclear ribonucleoprotein F, N-terminally processed 1 HSGPNS(0.969)ADS(0.03)ANDGFVR 149.95 2.71e-10 0.0 7148.8 7798.2 7998.4 7572.5 9330.2 8404.8 6876.1 6708.4 10135.0 7877.2 True False 7046.85680107064 7780.143747019975 7340.802426716859 8129.406911119472 8781.415979878973 8045.346296545737 7232.110812984301 7020.096754218229 8993.489573718616 9238.763524290767 0.7627489092607344 0.8421195895494288 0.7945654640273295 0.8799236921418597 0.9504968881161072 0.8708250054666654 0.7828007280378453 0.7598524126914636 0.9734516475145975 1.0 13.173484065227619 -14.522878745280089 0.18968457333565034 1.6720262828020713 0.8166475593362085 0.35765312781886127 0.06762552296419318 173.70292909663996 1.693275961051721 43.988631471285245 0.1962119675742985 3.000000000001719e-15 14.522878745280089 -0.8553787234658629 HSGPNSADSANDGFVR ddPTM_PC-9_Lapatinib_30min_R1 1 HSGPNSADSANDGFVR 16 0 P52597 P52597 HNRNPF Heterogeneous nuclear ribonucleoprotein F;Heterogeneous nuclear ribonucleoprotein F, N-terminally processed 0 77.726 0.0087064 4756000.0 19378.0 18492.0 31113.0 19354.0 23104.0 22997.0 19509.0 17726.0 20700.0 19763.0 False True 19101.66616651001 18449.1829101451 28555.009239653144 20777.357723051355 21745.068144211673 22013.47191862534 20519.080561729876 18549.614671944488 18368.548019336482 23179.008217457795 0.8240933342490107 0.7959435855521066 1.2319340401349137 0.8963868310552829 0.9381362627859928 0.9497158684315662 0.8852441126568765 0.8002764612669417 0.792464796034793 1.0 14.500531217232652 -7.43239585979786 3.8763585065326462 0.8463423270767286 0.9438420336749599 0.06704600489829626 0.12260829812743335 0.5622109214720574 15.43202836564361 0.05692588484352622 0.036045788686347446 3.6949123465905687e-08 7.43239585979786 0.09749970659823126 HSGS(ph)WPGHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSGSWPGHR 9 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 HS(0.314)GS(0.686)WPGHR 57.885 0.04573 4441200.0 14417.0 13296.0 13923.0 15081.0 17190.0 15393.0 14665.0 15123.0 12118.0 10227.0 True False 16857.513351270452 14615.939009797215 14254.977123271534 14236.060463261681 13821.74289944751 14585.763982172202 13275.825034594365 14726.037274143002 12295.202824996328 12081.074143112552 1.395365441150029 1.2098211497302827 1.179942855610925 1.1783770461650294 1.1440822840514822 1.2073234390741308 1.0988944258870346 1.2189344341155584 1.0177243082318017 1.0 13.560461111699901 -1.5228787452803376 0.14319088706231 0.9882359856729724 2.123891764325052 0.6600449001534199 0.062226711762433926 49.12337561622127 0.46789868687078395 0.24913934017396697 11.466157340901999 0.029999999999999995 1.5228787452803376 1.1356557786520796 HSHSHS(ph)PMSTR ddPTM_PC-9_AZD4547_30min_R2 2 HSHSHSPMSTR 11 0 P62995 P62995 TRA2B Transformer-2 protein homolog beta 1 HS(0.001)HS(0.26)HS(0.727)PMS(0.007)T(0.005)R;HSHS(0.005)HS(0.982)PMS(0.009)T(0.003)R 74.649 0.015673 737600.0 0.0 0.0 637.75 2470.7 697.65 829.41 0.0 2025.39 488.96 660.27 True False 0.0 0.0 629.2930183015528 1901.1182869344827 600.7933398155757 777.5468615843974 0.0 1712.4125143320618 514.8054273683758 637.1541482705468 0.0 0.0 0.9876621222818187 2.9837650623397254 0.9429324778726361 1.220343403075887 0.0 2.687595331491025 0.8079762625194122 1.0 9.31549863924493 -5.3468938705286115 4.329634966763798 1.4023999059246608 2.351910100519095e-08 0.29515515093254296 0.8324856678429212 0.25534178374139366 8.554635191150815 0.21949808632219017 0.4933918843538313 4.49889781989406e-06 5.3468938705286115 -1.4023998824055597 HSLEYS(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 1 HSLEYSLR 8 0 C9J5G3;F5H5G1;H3BLU2;Q13449 C9J5G3 LSAMP Limbic system-associated membrane protein 1 HS(0.001)LEY(0.257)S(0.742)LR 69.176 0.041582 8817400.0 22579.0 19747.0 26090.0 23198.0 22013.0 22875.0 26309.0 21398.0 26958.0 27227.0 True False 22257.019319518513 19701.277034752056 23944.98091031243 24904.058306259434 20718.238619223146 21896.689574229455 27671.15128907435 22392.229197239558 23921.70615967502 31933.150672302967 0.6969878903563064 0.6169537493160625 0.7498471151824355 0.7798810258913733 0.648800327654264 0.6857040133287386 0.8665337026413358 0.7012220443584769 0.7491182566092163 1.0 14.962767282443725 -14.522878745034951 0.1855389404676442 2.175775191239483 0.6681249736738363 0.653245452876487 0.06293837544675883 86.26994489166772 0.8358412603332792 37.3786380256434 0.18631503763105836 3.000000001695067e-15 14.522878745034951 -1.5076502175656468 HSLLLS(ph)SSPNRIPSSR ddPTM_PC-9_Lapatinib_30min_R1 1 HSLLLSSSPNRIPSSR 16 1 G1UD79;Q7Z309-3;Q7Z309-4 G1UD79 SPACIA2;FAM122B Protein FAM122B 1 HS(0.003)LLLS(0.508)S(0.423)S(0.066)PNRIPSSR 84.829 0.002301 25921000.0 22595.0 14989.0 15673.0 12660.0 14869.0 17103.0 13685.0 19030.0 17109.0 12637.0 True False 22272.791156584473 14954.293891421414 14384.426439529574 13591.058632521961 13994.43465357875 16371.544559040274 14393.542338780733 19914.203272430525 15182.004254242893 14821.288612255932 1.50275672644056 1.0089739349016857 0.9705246835038952 0.9169957476763069 0.9442117362188437 1.1045965696601046 0.9711397379360462 1.343621583346214 1.024337670726463 1.0 13.855383265364036 -4.75954239615489 24.995127543714663 1.034509196919435 1.5027573180421292 0.601192844458086 0.11510077032301924 36.43801847778768 479987.1287248748 0.03016377855090811 0.19011933875139087 1.7396328654763856e-05 4.75954239615489 0.4682481211226941 HSLLLSS(ph)SPNR ddPTM_PC-9_AZD4547_30min_R2 1 HSLLLSSSPNR 11 0 G1UD79;Q7Z309-3;Q7Z309-4 G1UD79 SPACIA2;FAM122B Protein FAM122B 1 HSLLLS(0.149)S(0.425)S(0.425)PNR 118.24 0.00061385 10203000.0 21038.0 23867.0 38553.0 36069.0 31836.0 42633.0 35164.0 51676.0 38138.0 32885.0 True False 27727.64638241584 31581.541005376916 38041.762029917285 27753.84931049493 27416.120929360965 39967.15177044842 38293.527878305664 43690.66159634619 40153.896819729875 31733.706159414978 0.8737601036300454 0.9952049359355111 1.1987809378083243 0.8745858164524765 0.8639432404029794 1.259454271419561 1.206714642340774 1.3767903873838492 1.2653390252627879 1.0 14.953728402083554 -6.773693513412889 24.999780643198573 1.2442750686876183 0.9715220461171568 0.5066847943376434 0.12729896513786026 185.6804266011725 378806.17002822587 0.04525403597041185 0.04019700243517374 1.6838619625249306e-07 6.773693513412889 -0.2727530225704615 HSLLLSS(ph)SPNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSLLLSSSPNR 11 0 G1UD79;Q7Z309-3;Q7Z309-4 G1UD79 SPACIA2;FAM122B Protein FAM122B 1 HSLLLS(0.178)S(0.735)S(0.087)PNR 113.69 0.00086791 6792000.0 31708.0 55415.0 56383.0 49878.0 55595.0 41210.0 51321.0 32371.0 40498.0 33376.0 True False 37075.53813845344 60916.23497502349 57727.384553718264 47083.49736665784 44701.55884204678 39048.87505394116 46459.50334813622 31521.295549909602 41090.206635311224 39426.80459572937 0.9403637580730898 1.5450462090357129 1.4641659435918672 1.1942001856208713 1.1337859940820252 0.990414400921825 1.1783735411610967 0.7994889738876765 1.0421896234462285 1.0 15.266889169358564 -6.339419500718614 1.7608267302523095 0.9978710301165316 1.3337109545951853 0.37474850553188177 0.173183278083431 0.3574343837654823 2.193189569839477 0.06234854674494087 0.07802142453226278 4.5769956458853986e-07 6.339419500718614 0.33583992447865374 HSLLLSS(ph)SPNRIPSSR ddPTM_PC-9_AZD4547_30min_R2 1 HSLLLSSSPNRIPSSR 16 1 G1UD79;Q7Z309-3;Q7Z309-4 G1UD79 SPACIA2;FAM122B Protein FAM122B 1 HSLLLS(0.186)S(0.628)S(0.186)PNRIPSSR 67.252 0.011937999999999999 34934000.0 19840.0 15316.0 13157.0 20948.0 21307.0 21503.0 16910.0 17032.0 15816.0 20203.0 True False 26148.707302363837 20266.59747929582 12982.529583368912 16118.762243373752 18348.890835591596 20158.414010741726 18414.957240989326 14400.095756424036 16652.00147099605 19495.69911931461 1.341255173376061 1.0395419705271032 0.6659176213130502 0.8267855461210268 0.941176344756631 1.0339928764478397 0.9445651129661423 0.7386293596497752 0.8541371801588137 1.0 14.250868270519078 -4.874443216807887 3.554522821806739 0.8736991994143741 1.3541761689379765 0.630606766815706 0.10858870035626977 0.16733371067419567 3.5778682341602184 0.029288059986874636 0.18385802896780393 1.3352321572598606e-05 4.874443216807887 0.4804769695236024 HSLLLSS(ph)SPNRIPSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSLLLSSSPNRIPSSR 16 1 G1UD79;Q7Z309-3;Q7Z309-4 G1UD79 SPACIA2;FAM122B Protein FAM122B 1 HS(0.004)LLLS(0.158)S(0.679)S(0.158)PNRIPSSR 67.418 0.011802 18561000.0 12138.0 9911.6 11541.0 13603.0 15388.0 11888.0 16263.0 15978.0 12369.0 10611.0 True False 14192.723663572231 10895.558144517607 11816.181209486234 12840.868011521037 12372.831863682275 11264.572352372052 14722.45090607625 15558.594430090378 12549.873225150992 12534.690303370213 1.132275574431721 0.8692323368841517 0.9426783529154452 1.0244264278367134 0.9870871608495649 0.898671772476368 1.1745364703679844 1.241242827188728 1.0012112721904822 1.0 13.613638731260872 -7.266793415080831 24.98091412783442 1.124351214190847 0.9721154154919825 0.29141764887155064 0.0960552959361169 481.4533090102253 2246359.6686233818 0.03823630389234357 0.02661731865915339 5.410116098014756e-08 7.266793415080831 -0.1522357986988644 HSLLLSSS(ph)PNR ddPTM_PC-9_AZD4547_30min_R2 1 HSLLLSSSPNR 11 0 G1UD79;Q7Z309-3;Q7Z309-4 G1UD79 SPACIA2;FAM122B Protein FAM122B 1 HSLLLS(0.043)S(0.183)S(0.774)PNR 129.54 0.00014423 6383300.0 30620.0 38051.0 57661.0 60681.0 49310.0 64271.0 49264.0 69479.0 56214.0 49733.0 True False 40356.52306443448 50350.24162213924 56896.37746497193 46691.93296210438 42464.15765255649 60252.12420984895 53648.40056298631 58742.617018587654 59185.35727684444 47991.86280754705 0.8409034512010678 1.0491412226287105 1.185542176037905 0.9729135363914599 0.88481995005784 1.255465420283163 1.1178645175354547 1.2240120216660975 1.2332373409672512 1.0 15.550502192000359 -6.768872865010628 24.999987395209494 1.17710090278301 1.0004198818535386 0.3917841360076877 0.11071412390585755 189.04197569054452 635774.2679626526 0.03918237181112796 0.03523230853692948 1.7026568697394535e-07 6.768872865010628 -0.17668102092947136 HSLLLSSS(ph)PNR ddPTM_PC-9_Lapatinib_30min_R1 2 HSLLLSSSPNR 11 0 G1UD79;Q7Z309-3;Q7Z309-4 G1UD79 SPACIA2;FAM122B Protein FAM122B 1 HSLLLS(0.014)S(0.229)S(0.756)PNR;HSLLLS(0.05)S(0.186)S(0.764)PNR 116.9 0.0006886 16899400.0 45820.0 91387.0 94324.0 86778.0 125015.0 108374.0 109128.0 118859.0 120035.0 81687.0 True False 45166.59839764108 91175.3990163006 86569.04482116921 93159.94360292164 117661.86348894672 103739.096652133 114778.11387259503 124381.62305611254 106515.39427541339 95806.48910891422 0.4714356910239663 0.9516620415204973 0.9035822690752842 0.9723761351594469 1.2281199800066465 1.0827982281471653 1.1980202483165163 1.2982588571293296 1.111776407486607 1.0 16.547835754594402 -4.545412593573288 0.7134043152766261 1.1669702898130252 1.8184704142022216e-14 0.7626583629110536 0.10746439647992 1.8710656848963703 0.5725986439158283 0.043725473838592585 1.8997318451313956 2.8483109956559427e-05 4.545412593573288 -1.166970289813007 down HSLS(ph)LDDIR ddPTM_PC-9_AZD4547_30min_R2 4 HSLSLDDIR 9 0 Q96NE9-3;Q96NE9-2;Q96NE9 Q96NE9-3 FRMD6 FERM domain-containing protein 6 1 HSLS(1)LDDIR;HS(0.014)LS(0.986)LDDIR;HSLS(1)LDDIR;HS(0.002)LS(0.998)LDDIR 147.3 0.00038937 70304300.0 71502.6 66747.7 107814.2 138567.0 131952.1 110415.0 102224.4 131640.0 115345.8 131752.0 True False 94238.9394535282 88322.58870258501 106384.51326345328 106622.51898880891 113632.82857403989 103510.73259526781 111322.1735650969 111298.06278626474 121442.74350488218 127139.40258218771 0.7412252813804799 0.6946909212153168 0.8367548620081199 0.8386268680150836 0.8937656325747113 0.8141514785579912 0.8755914476877775 0.8754018071959829 0.9551935988245422 1.0 16.95605168888882 -1.7815338298615022 0.13475318235027114 1.0373753797047238 9.186939859999333e-17 0.8075529460801727 0.03780347304320357 32.797675137601765 0.31785002703497284 0.19420240029099994 6.426766161786684 0.01653735960114661 1.7815338298615022 -1.0373753797047238 HSLS(ph)LDDIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 HSLSLDDIR 9 0 Q96NE9-3;Q96NE9-2;Q96NE9 Q96NE9-3 FRMD6 FERM domain-containing protein 6 1 HSLS(1)LDDIR;HS(0.001)LS(0.999)LDDIR;HS(0.011)LS(0.989)LDDIR;HSLS(1)LDDIR;HSLS(1)LDDIR;HSLS(1)LDDIR;HS(0.144)LS(0.856)LDDIR 195.83 0.00011567 49308600.0 86373.79999999999 91158.9 118723.9 124648.2 137869.5 130189.9 110867.0 122110.2 116399.8 91483.8 True False 100995.17837968809 100208.55314381789 121554.72803889825 117664.56546891661 110854.96117948672 123362.51245777945 100364.87515242927 118904.93663645146 118101.92686821304 108069.08875463772 0.9345427035938983 0.9272637929920317 1.12478720270214 1.088790206569287 1.0257786241834064 1.1415152462131353 0.9287102936557534 1.1002677824591975 1.0928372602118823 1.0 16.72159439919615 -5.244976477813098 24.195059899389655 1.0640400701105883 0.930903198131891 0.43367988746147057 0.06029313748243167 479.3253056105668 704446.261565699 0.014824112547108968 0.03894666315840294 5.688837417978921e-06 5.244976477813098 -0.13313687197869728 HSLS(ph)LDDIR ddPTM_PC-9_Lapatinib_30min_R1 5 HSLSLDDIR 9 0 Q96NE9-3;Q96NE9-2;Q96NE9 Q96NE9-3 FRMD6 FERM domain-containing protein 6 1 HS(0.002)LS(0.998)LDDIR;HSLS(1)LDDIR;HSLS(1)LDDIR;HSLS(1)LDDIR;HS(0.013)LS(0.987)LDDIR 158.47 0.00011567 57626700.0 142481.4 129320.4 142856.1 127475.7 118146.3 109716.8 92595.5 102100.7 132088.1 102219.4 True False 140449.5891081112 129020.96655922166 131111.0228984931 136850.68822446922 111197.16691856278 105024.46822635265 97389.641916739 106844.67125893041 117210.94722864352 119887.88709121115 1.1715077520822152 1.0761801687359962 1.0936135924953232 1.1414888655127662 0.9275096059868297 0.8760223469986559 0.8123392969853961 0.8912048902625382 0.9776713066889652 1.0 16.87132637742399 -6.316559745633776 5.046841418919633 0.899521907875089 1.1157830827505502 0.7678887446437217 0.05536739078252697 0.09827586346017672 5.470550442439041 0.0176464862409768 0.02036972558313806 4.824366069770502e-07 6.316559745633776 0.21626117487546115 HSLSGS(ph)SPGMK ddPTM_PC-9_AZD4547_30min_R2 1 HSLSGSSPGMK 11 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 HS(0.005)LS(0.261)GS(0.367)S(0.367)PGMK 65.695 0.038793 22874000.0 50237.0 41291.0 75529.0 87855.0 82124.0 76556.0 60460.0 85189.0 71390.0 73983.0 True False 66211.32100548658 54637.50826048601 74527.43611022802 67601.38709621924 70722.50016342627 71768.94121779944 65840.82287346036 72024.997498474 75163.52965442637 71392.87768867248 0.9274219382809942 0.7653075492873016 1.043905758151739 0.9468925932781834 0.9906100223586789 1.0052675216534468 0.922232371141792 1.0088541018413355 1.0528155200886677 1.0 16.123492534535487 -5.268564604093555 24.97338589645286 0.9923425108844515 0.8463647414179988 0.5709817910414112 0.05190255882439312 330.48538898130005 1158330.0124374758 0.012900893954313541 0.027770805404103805 5.388096880097331e-06 5.268564604093555 -0.1459777694664527 HSLSGSS(ph)PGMK ddPTM_PC-9_AZD4547_30min_R2 1 HSLSGSSPGMK 11 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 HSLS(0.002)GS(0.124)S(0.875)PGMK 72.096 0.015918 2848600.0 24022.0 29322.0 46853.0 48377.0 46940.0 48306.0 36821.0 62165.0 41832.0 51354.0 True False 31660.496311360064 38799.76307703785 46231.698606793645 37224.43006719935 40423.19124337868 45285.418183643684 40097.99766827133 52558.827659587834 44043.154118279395 49556.11209094107 0.6388817640346659 0.7829460673960036 0.9329161763528433 0.7511571932618183 0.815705460694688 0.9138210459395971 0.8091433322026347 1.0605922345791865 0.8887532185223738 1.0 15.596775385285797 -2.490460836271913 0.1817204847132262 1.020444133113823 1.3280463323314497e-14 0.5364801101124819 0.08058468215404842 33.220835489140086 0.5121987075461027 0.1895592951901514 8.74598502235086 0.0032325046904678003 2.490460836271913 -1.0204441331138097 HSLSGSS(ph)PGMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSLSGSSPGMK 11 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 HSLS(0.009)GS(0.166)S(0.825)PGMK 59.79600000000001 0.045977 41518000.0 44316.0 53276.0 70862.0 76022.0 87260.0 63220.0 78784.0 58180.0 58191.0 52763.0 True False 51817.823519102545 58564.889191182025 72551.61882563146 71762.73380664946 70162.02940115125 59904.63190755062 71321.00917323444 56652.83664680552 59041.9332884438 62328.514228321816 0.8313662560490932 0.9396163203352982 1.1640197062914153 1.1513628183686235 1.1256810830454533 0.9611111808009408 1.1442757790113738 0.9089393088895853 0.9472700259172132 1.0 15.92760470210123 -7.783091689783198 24.990342472865827 0.9460784825291569 1.0497727414255238 0.14074889225821607 0.10490510897438747 487.4173340742582 562551.9392407736 0.06106305435812918 0.029375329726285582 1.647814462396043e-08 7.783091689783198 0.10369425889636685 HSLSIPPVSS(ph)PPEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSLSIPPVSSPPEQK 15 0 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 1 HSLSIPPVS(0.262)S(0.738)PPEQK 53.21 0.046058999999999996 15267000.0 74598.0 76891.0 100460.0 111490.0 126130.0 116990.0 119630.0 116840.0 98996.0 92476.0 True False 87225.96802233998 84524.23032508387 102855.34739667177 105243.5767554568 101415.73193178084 110854.83845087554 108297.78035380325 113773.07380221321 100443.62921796806 109241.1667603866 0.7984715891369457 0.7737397249745811 0.9415438377940277 0.9634058283751377 0.92836551402119 1.0147716445946466 0.9913641859148886 1.0414853408858866 0.9194668291879804 1.0 16.737157102572773 -5.350520580516545 3.195992080211576 0.9804191405507761 0.7825933992192051 0.8186153467178019 0.035844213199677864 0.09615895582046201 1.866033594801395 0.009838475160047636 0.02460171865430059 4.461484818214838e-06 5.350520580516545 -0.19782574133157094 HSLSIPPVSS(ph)PPEQK ddPTM_PC-9_Lapatinib_30min_R1 2 HSLSIPPVSSPPEQK 15 0 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 1 HSLSIPPVS(0.232)S(0.768)PPEQK;HSLSIPPVS(0.171)S(0.829)PPEQK 105.02 0.00061791 27402000.0 140657.0 106445.0 146925.0 113647.0 142626.0 139598.0 115628.0 130676.0 138963.0 106579.0 True False 138651.20538666515 106198.53314246108 134845.39364690147 122004.97949527862 134237.0190935048 133627.71895883218 121614.65206785078 136747.68401619175 123311.52359473691 125001.03814240926 1.1092004310292587 0.8495812092494212 1.0787541899714215 0.9760317298827763 1.0738872339649956 1.0690128733698583 0.9729091363969274 1.0939723865365019 0.9864839958709178 1.0 16.931580551057664 HSMGPGGYGDNLGGGQMYS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSMGPGGYGDNLGGGQMYSPR 21 0 P40425 P40425 PBX2 Pre-B-cell leukemia transcription factor 2 1 HSMGPGGYGDNLGGGQMY(0.181)S(0.819)PR 63.272 0.0030066 5732000.0 12708.0 17894.0 16468.0 16389.0 14080.0 14680.0 17241.0 14140.0 16536.0 9840.8 True False 14859.213405559058 19670.398062673838 16860.659575237776 15470.77746385491 11321.125074125712 13910.154957336961 15607.807665969422 13768.839982568406 16777.80771696149 11624.859140270068 1.2782273940924371 1.692097755794128 1.450396892709882 1.3308356924740763 0.9738720218043606 1.1965869684519723 1.3426233795729952 1.1844306942930003 1.4432697647785615 1.0 13.504925614577427 -5.874444699444312 3.516789423224199 1.2039492833737078 1.497814980201633 0.3762205145540757 0.16174047296201388 0.23927777478378734 5.728540985650707 0.046190445150091214 0.07281068015611815 1.3352275989232118e-06 5.874444699444312 0.2938656968279252 HSPAPPPDPGFPAPS(ph)PPPADSPSEGFSLK ddPTM_PC-9_AZD4547_30min_R2 2 HSPAPPPDPGFPAPSPPPADSPSEGFSLK 29 0 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 HSPAPPPDPGFPAPS(1)PPPADSPSEGFSLK;HSPAPPPDPGFPAPS(1)PPPADSPSEGFSLK 126.86 1.8624e-13 18358700.0 59680.0 62073.0 89315.0 126871.0 97482.0 103620.0 75447.0 102818.0 93296.0 80916.0 True False 78656.99857888474 82136.88334632597 88130.62474261578 97622.85108741026 83948.3069618032 97140.62501944207 82161.63683979439 86929.84062259305 98227.43609244109 78083.15546891362 1.0073491280741027 1.0519155233042061 1.1286765271378183 1.250242136106753 1.0751141710099639 1.2440663346157366 1.0522325378167443 1.113298253644494 1.257984971311095 1.0 16.252723735311 -5.186750003539659 3.099800052731848 1.1471042344926656 1.0166286396735695 0.22493881962890605 0.08343241004517882 0.35518347866210503 6.5397175347849945 0.020927102409775102 0.06935682547875151 6.5050403751158335e-06 5.186750003539659 -0.1304755948190961 HSPAPPPDPGFPAPS(ph)PPPADSPSEGFSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HSPAPPPDPGFPAPSPPPADSPSEGFSLK 29 0 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 HSPAPPPDPGFPAPS(0.999)PPPADS(0.001)PSEGFSLK;HSPAPPPDPGFPAPS(1)PPPADSPSEGFSLK;HSPAPPPDPGFPAPS(1)PPPADSPSEGFSLK;HSPAPPPDPGFPAPS(1)PPPADSPSEGFSLK 124.17 2.2147e-13 16101500.0 63356.4 65283.8 76985.0 94553.9 128697.0 128614.0 153381.0 137877.0 134441.0 117679.0 True False 74081.3871740607 71764.74421839649 78820.6143672382 89256.35153087975 103479.74670914467 121869.25542799279 138851.64129772352 134257.87484275716 136406.94528761602 139013.2711535484 0.5329087400024808 0.5162438350157811 0.567000644709498 0.6420707231059315 0.7443875383296689 0.8766735320786816 0.9988373062910924 0.9657917818109708 0.9812512442567188 1.0 17.084863093453706 -6.516248248542937 1.0271647750499096 0.9967476396038255 0.5215336480259197 0.9918379149230523 0.01753879017292257 0.04266683976147396 0.0966063546211424 0.009221852180893164 0.010797414942873503 3.0461532698700114e-07 6.516248248542937 -0.4752139915779058 HSPAPPPDPGFPAPS(ph)PPPADSPSEGFSLK ddPTM_PC-9_Lapatinib_30min_R1 2 HSPAPPPDPGFPAPSPPPADSPSEGFSLK 29 0 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 HSPAPPPDPGFPAPS(0.999)PPPADS(0.001)PSEGFSLK;HSPAPPPDPGFPAPS(0.999)PPPADSPSEGFSLK 108.3 1.0702999999999999e-11 5702800.0 25917.1 20439.3 25719.8 22122.9 32833.0 42234.0 43680.0 38439.0 47576.0 35634.0 True False 25547.517401385943 20391.97405663685 23605.21732529909 23749.891865830967 30901.82749216164 40427.7502722626 45941.53667211854 40225.0162684686 42217.48988250978 41793.28942067959 0.6112827622691231 0.4879246007983944 0.5648087923325575 0.5682704614793821 0.7393968725723516 0.9673263538872987 1.0992562994906636 0.9624754793425042 1.0101499658847215 1.0 15.350983692747699 -6.594467841097558 2.112705560800537 1.0194896185115416 0.5504771405417914 0.9604707585153697 0.04327665803020796 0.0557106408921922 0.5056805594619548 0.016322263878912936 0.016789215665306906 2.544088172346382e-07 6.594467841097558 -0.4690124779697502 HSPIAPS(ph)SPSPQVLAQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSPIAPSSPSPQVLAQK 17 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 HS(0.002)PIAPS(0.496)S(0.496)PS(0.005)PQVLAQK 83.229 0.0022353 4480700.0 95382.0 92633.0 107930.0 131040.0 147000.0 152420.0 138870.0 136720.0 128900.0 114430.0 True False 111528.28871962798 101828.99204983018 110503.46052680418 123698.25363741216 118196.40524832926 144426.82687992504 125715.22826826568 133131.24486681438 130784.91864515818 135175.25317261828 0.8250643967887138 0.753310903141383 0.8174829189015217 0.9150954093605429 0.8743938145053289 1.0684413270193216 0.9300165919255045 0.9848788276120799 0.9675211666010075 1.0 17.044471532913605 -6.023052224878206 1.2594141010152715 0.9821971285415068 0.7834441924394625 0.7408583079356936 0.0466581567173327 0.22135620153517502 0.7137679077540662 0.016809006071327 0.030971056537776164 9.483044207265421e-07 6.023052224878206 -0.19875293610204425 HSPIAPS(ph)SPSPQVLAQK ddPTM_PC-9_Lapatinib_30min_R1 1 HSPIAPSSPSPQVLAQK 17 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 HS(0.01)PIAPS(0.476)S(0.476)PS(0.037)PQVLAQK 80.238 0.0033287 11821000.0 137920.0 118110.0 147970.0 117710.0 145600.0 147100.0 125570.0 126910.0 158230.0 118090.0 True False 135953.2355085695 117836.52355165666 135804.4777807176 126366.78606904924 137036.09426061367 140808.87590684832 132071.40018127137 132806.7019077331 140408.47116423256 138501.6991549657 0.9815997661982124 0.8507947864221699 0.9805257163579614 0.9123843739105393 0.9894181450242556 1.016658111531911 0.9535724181513495 0.9588813907556425 1.0137671380271907 1.0 17.079544149970523 -6.270049713930158 24.42084411298874 0.9863001800690931 0.9290881733996497 0.33605533682302746 0.03938083449041018 533.932132530312 1514348.6954242706 0.011663587003037382 0.013431073848766966 5.369703255611063e-07 6.270049713930158 -0.05721200666944348 HSPIAPSS(ph)PSPQVLAQK ddPTM_PC-9_AZD4547_30min_R2 2 HSPIAPSSPSPQVLAQK 17 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 HSPIAPS(0.124)S(0.865)PS(0.011)PQVLAQK;HS(0.057)PIAPS(0.149)S(0.724)PS(0.07)PQVLAQK 128.74 1.5023e-05 14206000.0 141408.0 124749.0 246550.0 258140.0 237975.0 205920.0 158424.0 214534.0 166268.0 225180.0 True False 186372.8025308801 165071.6746503443 243280.5859070916 198629.81122324348 204936.27899750878 193043.7898475536 172523.4290920456 181382.69980088534 175056.58703715066 217296.51673945744 0.8576888637121807 0.7596609330294434 1.119578857303035 0.9140956983742372 0.9431181045724317 0.8883887912433345 0.793953956007976 0.8347243781103337 0.8056115655413233 1.0 17.729305522757258 -7.013497524715304 10.188914803834164 0.8442540221440735 0.9203894268782283 0.0686265786543867 0.09918099332707578 0.784443144467691 566.8752844967544 0.037004310726634966 0.03024307551876539 9.693987944249391e-08 7.013497524715304 0.07613540473415481 HSPIAPSS(ph)PSPQVLAQK ddPTM_PC-9_Lapatinib_30min_R1 1 HSPIAPSSPSPQVLAQK 17 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 HSPIAPS(0.074)S(0.901)PS(0.025)PQVLAQK 118.02 6.6999e-05 10312000.0 76929.0 72227.0 83464.0 70126.0 75147.0 80433.0 73423.0 75248.0 80466.0 57246.0 True False 75831.97835294902 72059.7628191138 76601.91210035689 75283.29997347815 70727.00120468638 76993.06808848081 77224.4836785018 78744.29678632974 71403.07173545555 67140.89482449977 1.129445452747792 1.0732618772429456 1.1409128862608602 1.121273408259778 1.0534116560340814 1.1467387840113499 1.1501854999156567 1.1728216758528496 1.0634810858880674 1.0 16.034904144321963 -8.52836105731542 6.913241592822846 1.0000105721337371 1.1215560127176767 0.5734151528014989 0.03390833567761419 0.0838318408908509 34.568465813807116 0.03397565976392119 0.008791500436965203 2.9623675562208747e-09 8.52836105731542 0.12154544058393957 HSPQQPSNGS(ph)LR ddPTM_PC-9_AZD4547_30min_R2 3 HSPQQPSNGSLR 12 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 HSPQQPSNGS(1)LR;HSPQQPSNGS(1)LR;HSPQQPS(0.225)NGS(0.775)LR 186.29 2.4167e-35 20087000.0 3331.3100000000004 5283.6 11534.0 15054.3 13350.1 12898.7 9727.3 12687.0 11252.699999999999 10836.6 True False 4390.597284447458 6991.420373570599 11381.051623818275 11583.763721616448 11496.669054499998 12092.142249935097 10593.010855722976 10726.515668256907 11847.494749157644 10457.213932404331 0.4198630068035692 0.668573906851605 1.0883445339634106 1.1077294388824939 1.0994007704934343 1.1563445414905902 1.012985956316514 1.0257527232007826 1.1329494476961186 1.0 13.352210911698588 -5.085752385971433 2.575096041653502 1.0837074730649527 0.42359450725542774 0.9464838332950365 0.05226068095311264 0.06378404240188337 0.7612530545332961 0.014517082925494425 0.06726221059761875 8.208194030705784e-06 5.085752385971433 -0.660112965809525 down HSPQQPSNGS(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 4 HSPQQPSNGSLR 12 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 HSPQQPS(0.001)NGS(0.999)LR;HS(0.001)PQQPS(0.015)NGS(0.985)LR;HSPQQPS(0.001)NGS(0.999)LR;HSPQQPS(0.1)NGS(0.9)LR 180.27 8.453200000000001e-26 65293000.0 52667.100000000006 37872.0 41505.8 36008.1 36040.9 38858.2 26785.6 29722.3 42990.6 27941.300000000003 True False 51916.05749603677 37784.309710848735 38093.353341021284 38656.255793500335 33921.04512113566 37196.32536888842 28172.427305052614 31103.306564590748 38148.545916912415 32770.916475558035 1.5842113397944793 1.1529830036651525 1.1624134274497009 1.1795903182119378 1.035096017117356 1.1350407425020002 0.8596777366926808 0.9491131133848191 1.1640976212967753 1.0 15.000128399584659 -1.5228787452809391 0.6527350931112278 1.0226990474676374 48.041789938391595 0.7301317942580006 0.09615870509991412 118.99616063570068 0.7601100674974429 0.041070856746775526 8089.983598922105 0.029999999999958445 1.5228787452809391 47.019090890923955 HSPS(ph)PPPPTPTESR ddPTM_PC-9_AZD4547_30min_R2 2 HSPSPPPPTPTESR 14 0 Q92922 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 1 HS(0.12)PS(0.88)PPPPTPTESR;HS(0.011)PS(0.989)PPPPTPTESR 106.82 0.00047578 7812200.0 20514.2 16632.2 28315.0 37142.0 33221.0 22642.0 21309.9 28130.0 24067.0 25237.0 True False 27037.288878132666 22008.233389601966 27939.52459930767 28579.485738179676 28608.837586201178 21226.192160685234 23206.439817253617 23783.154863093456 25339.1324862457 24353.46031154496 1.1102031716337006 0.9037004642485561 1.1472507086010568 1.1735287459183503 1.1747339893476625 0.871588344701175 0.9529011286438178 0.976582159530687 1.040473598498587 1.0 14.571839154716507 -6.756940021578789 24.999954813650795 0.965882437785725 1.0973739466912913 0.3959511751295973 0.08236995872214205 133.89215236970455 743949.1250799715 0.029776577720109453 0.028814602825201138 1.750088368622319e-07 6.756940021578789 0.13149150890556627 HSPS(ph)PPPPTPTESR ddPTM_PC-9_Lapatinib_30min_R1 1 HSPSPPPPTPTESR 14 0 Q92922 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 1 HS(0.015)PS(0.837)PPPPT(0.112)PT(0.035)ES(0.001)R 118.73 0.0015168 0.0 5388.8 4457.2 6955.4 4292.7 2900.3 4937.5 3612.7 3730.4 5147.6 4089.1 True False 5311.954723815109 4446.879627249554 6383.553860620428 4608.39947802741 2729.7100562091896 4726.334634874661 3799.74792892314 3903.7280024947377 4567.823081368911 4795.895486616742 1.1076043543147391 0.9272261331921974 1.3310452403381494 0.960904901052879 0.5691763016576618 0.9854957532047569 0.7922916459557101 0.813972700904001 0.952444250321075 1.0 12.227584504176807 -5.996507556463908 24.99979812798332 0.8391810512225175 1.1097336611444881 0.39823708306059025 0.1476916610387817 100.25244898448953 717615.4543890493 0.03983280656290216 0.0587671760544052 1.0080740693265814e-06 5.996507556463908 0.2705526099219706 HSPSPPPPT(ph)PTESR ddPTM_PC-9_AZD4547_30min_R2 1 HSPSPPPPTPTESR 14 0 Q92922 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 1 HS(0.084)PS(0.207)PPPPT(0.399)PT(0.305)ES(0.006)R 100.11 0.0062207 0.0 3635.3 2787.4 4103.6 6321.5 3668.7 4017.4 2291.0 5535.9 4360.4 4153.8 True False 4791.249781062663 3688.3725394221165 4049.183582755393 4864.17584120141 3159.3643313716107 3766.1913429174483 2494.894561744917 4680.453857326667 4590.881842066968 4008.3767263183186 1.1953092506510512 0.9201661398752494 1.0101803945146033 1.21350266537176 0.7881904688817702 0.9395801842150409 0.622420179561433 1.167668155190006 1.1453219483897359 1.0 11.968802390912273 -4.752759060288931 24.73619549760516 0.9738322645389045 1.1953097305145608 0.12732036594472285 0.1698338918039879 656.4558855682967 1870532.7915888205 0.04348686804642338 0.4982344018969859 1.7670178623734333e-05 4.752759060288931 0.22147746597565632 HSPT(ph)EDEESAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSPTEDEESAK 11 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 HS(0.279)PT(0.721)EDEESAK 105.65 0.0061901000000000005 4248500.0 13052.0 35181.0 20539.0 16165.0 16584.0 11303.0 12918.0 8774.6 6285.4 8277.9 True False 15261.44581124936 38673.53717687091 21028.72765459125 15259.327457637097 13334.484249240111 10710.250782205703 11694.31352177907 8544.276047457195 6377.312084191451 9778.617742179656 1.5606956129821656 3.954908372177617 2.150480590307229 1.5604789817907114 1.3636369271008901 1.095272467396643 1.195906602559597 0.8737713522231081 0.6521690746416217 1.0 13.255414831900993 -5.818703896208073 1.9091565766947112 1.031559412349114 2.8005197484536786 0.5907936130373506 0.5748803837845532 0.2129291628567161 1.5850262192738886 0.17195088965506616 0.3267759736010258 1.5180850514228412e-06 5.818703896208073 1.7689603361045645 HSPT(ph)EDEESAK ddPTM_PC-9_Lapatinib_30min_R1 2 HSPTEDEESAK 11 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 HS(0.165)PT(0.835)EDEESAK;HS(0.42)PT(0.58)EDEESAK 97.463 0.013153999999999999 12774900.0 17459.5 35128.0 19646.0 24068.8 31500.0 26616.5 33839.0 39260.0 26488.0 31093.9 True False 17210.52432831983 35046.663274257895 18030.781715753088 25838.899843163064 29647.231931382772 25478.174341091926 35591.01784450139 41084.16292567643 23504.642508994446 36468.4391849826 0.4719292822218446 0.9610135245022995 0.4944215359558907 0.7085277138431334 0.8129558762029843 0.6986362704435025 0.9759402551880387 1.1265676251533832 0.6445201120280866 1.0 15.154360834549175 -7.257603879554556 24.346244938235714 0.9473043087676284 0.7008804994126667 0.3218104413233561 0.17399655913938794 273.011831459369 1732980.0222107742 0.0648671167434404 0.048280418898499 5.5258121939751774e-08 7.257603879554556 -0.24642380935496166 HSPT(ph)EDEESAKAEADAYIR ddPTM_PC-9_Lapatinib_30min_R1 2 HSPTEDEESAKAEADAYIR 19 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 HS(0.153)PT(0.841)EDEES(0.006)AKAEADAYIR;HS(0.185)PT(0.711)EDEES(0.103)AKAEADAY(0.001)IR 57.595 0.018806 14869900.0 28487.0 38061.0 32255.0 29874.0 40833.0 38286.0 39669.0 42085.0 36463.0 32116.0 True False 28080.770156124003 37972.87209296086 29603.118407900613 32071.033616742592 38431.28322076675 36648.59702902508 41722.86671809231 44040.42273884599 32356.152967587732 37667.20780811996 0.7454964620465073 1.0081148644305673 0.7859122066785911 0.851431138196259 1.0202848965216393 0.9729576244598811 1.1076708135796056 1.1691979655936204 0.8590005697372844 1.0 15.201021472811423 -6.2801119790012 5.3016423074904555 1.0328954360070661 0.8541241522540318 0.41895022863582787 0.09966616566807496 0.1779312022650745 16.120335186154758 0.03031121087540731 0.03597350120205116 5.246721607191757e-07 6.2801119790012 -0.1787712837530343 HSPT(ph)GPPGFPR ddPTM_PC-9_Lapatinib_30min_R1 1 HSPTGPPGFPR 11 0 P98175-5;P98175-2;P98175 P98175-5 RBM10 RNA-binding protein 10 1 HS(0.477)PT(0.523)GPPGFPR 81.676 0.031019 4056100.0 9601.2 11706.0 14857.0 16436.0 18266.0 16270.0 18917.0 16491.0 16188.0 14515.0 True False 9464.285127355555 11678.895476214499 13635.514809678489 17644.758268888698 17191.629792337724 15574.170027222424 19896.429698408112 17257.23206335533 14364.736972802859 17023.89840997824 0.5559411187397736 0.6860294390249141 0.8009631214485096 1.0364698991945671 1.0098527010864429 0.9148415746004402 1.1687352226412602 1.0137062409418707 0.8437983255576312 1.0 14.055273826252018 -5.379652895526409 1.6966405359058951 1.0048132851361016 0.5723620012566051 0.7699379813441593 0.0835048041629044 0.1960514640485319 1.0200052829520931 0.02505253800332982 0.09272807441084 4.172026943298496e-06 5.379652895526409 -0.4324512838794965 HSQAVEELAEQLEQTK ddPTM_PC-9_AZD4547_30min_R2 2 HSQAVEELAEQLEQTK 16 0 P35579 P35579 MYH9 Myosin-9 0 ; 147.09 1.0269000000000001e-05 3720500.0 32341.0 37807.0 39308.0 43532.0 39920.0 41485.0 38036.0 42959.0 36866.0 39019.0 False True 42624.765265410715 50027.37339381932 38786.75023660906 33496.36996269555 34377.797069358276 38890.93639192766 41421.13031450445 36320.67364961367 38814.66149656933 37652.95668645927 1.1320429792632833 1.3286439577747722 1.0301116738212892 0.8896079593861348 0.9130171995688507 1.0328786850864646 1.1000764338222684 0.964616775040014 1.0308529505341033 1.0 15.200475536064463 -5.383308002634571 5.852300054537134 0.9897706587128977 1.2281192031233328 0.6322667273554796 0.07216175698466351 0.13617315006103162 5.888912076377724 0.019617662018875392 0.04158989056435233 4.137061693981712e-06 5.383308002634571 0.23834854441043507 HSQAVEELAEQLEQTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSQAVEELAEQLEQTK 16 0 P35579 P35579 MYH9 Myosin-9 0 84.375 0.011656999999999999 0.0 10755.0 13127.0 13110.0 15107.0 17654.0 13866.0 13198.0 14265.0 14854.0 11681.0 False True 12575.609079067333 14430.161806679294 13422.592119951869 14260.603767554825 14194.825430299374 13138.842550302072 11947.789894754616 13890.55886501685 15071.211648992869 13798.67283325488 0.9113636674361932 1.0457644717760481 0.9727451532587501 1.0334764755916737 1.0287094709637412 0.9521816126140326 0.8658651479844044 1.0066590485093991 1.0922218267738883 1.0 13.752241893729911 -8.00502044102722 24.994027652050008 1.0472207718648587 0.9762756962404714 0.21005585801916327 0.05665850889605112 333.5950424043052 1660779.3308252264 0.03335190324564829 0.015326818185731174 9.88506567321176e-09 8.00502044102722 -0.07094507562438734 HSQAVEELAEQLEQTK ddPTM_PC-9_Lapatinib_30min_R1 1 HSQAVEELAEQLEQTK 16 0 P35579 P35579 MYH9 Myosin-9 0 80.488 0.0067348 4050800.0 19196.0 19641.0 19533.0 23152.0 27664.0 20512.0 19114.0 21010.0 20920.0 22069.0 False True 18922.26151988473 19595.522471239452 17927.072139560456 24854.675312807944 26036.857909516613 19634.74957580742 20103.629394479707 21986.201300775898 18563.76930263378 25883.59724490595 0.7310522312971295 0.7570633357423289 0.6926035809450177 0.960248109164946 1.005921150107558 0.7585788555596404 0.7766937958531334 0.8494260319671337 0.7172020614826728 1.0 14.659750513369112 -12.096205628566151 2.246992567270081 4.686775216444102 0.8102030123187872 0.2573988663842809 0.09884987081771118 5371641.193812057 457424.10371289705 101506290.98268716 0.02779461350122135 8.012985768921189e-13 12.096205628566151 -3.8765722041253143 HSQAVEELAEQLEQTKR ddPTM_PC-9_AZD4547_30min_R2 2 HSQAVEELAEQLEQTKR 17 1 P35579 P35579 MYH9 Myosin-9 0 ; 127.57 1.3517000000000001e-05 16252900.0 98872.0 100301.0 130076.0 161127.0 138544.0 127868.0 109904.0 143203.0 126203.0 142024.0 False True 130311.23933464289 132721.3367570415 128351.10724985144 123981.65953733446 119309.55704351632 119872.39374624597 119685.24308774067 121074.2668275711 132873.8329314691 137051.78298874132 0.9508175413182901 0.9684028464477872 0.9365154137425221 0.9046336854115895 0.8705436327910998 0.8746503776320326 0.8732848305780356 0.8834198591748146 0.9695155366375976 1.0 17.064361571606575 -5.615684661648161 3.0696293299189854 0.9010944294996567 0.9589383610373023 0.15602997089058923 0.041671095932743936 0.34873526076119826 6.546156450329883 0.011512100380270741 0.022439184900299655 2.4227875782714384e-06 5.615684661648161 0.057843931537645665 HSQFIGYPITLFVEK ddPTM_PC-9_AZD4547_30min_R2 1 HSQFIGYPITLFVEK 15 0 P07900;P07900-2;G3V2J8;Q58FG0 P07900 HSP90AA1;HSP90AA5P Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-alpha A5 0 59.345 0.046303 9094100.0 22930.0 19638.0 49371.0 67166.0 47751.0 51113.0 35848.0 59072.0 37725.0 37037.0 False True 30221.263026371107 25985.599457979297 48716.30828156168 51681.91640435562 41121.597892257654 47916.896029904754 39038.40255322206 49943.779739518555 39719.06648288607 35740.345903185436 0.8455783586492254 0.7270662552726798 1.363062025575408 1.4460385062963075 1.1505651904894576 1.3406948035618775 1.0922782521179426 1.3974061659841743 1.1113229455159253 1.0 15.125265976726709 -5.257780624074299 24.99179345087432 1.2546816676483092 0.7863222639116607 0.6112980271825987 0.14345189867018432 178.8432417843113 1221608.2266440657 0.03488259197463929 0.08508919056731551 5.523563815615905e-06 5.257780624074299 -0.4683594037366485 HSQPAT(ph)PTPLQSR ddPTM_PC-9_AZD4547_30min_R2 3 HSQPATPTPLQSR 13 0 Q9NR12-2;Q9NR12 Q9NR12-2 PDLIM7 PDZ and LIM domain protein 7 1 HS(0.071)QPAT(0.919)PT(0.009)PLQS(0.001)R;HSQPAT(0.995)PT(0.005)PLQSR;HSQPAT(0.999)PT(0.001)PLQSR 132.15 0.00012494 36460700.0 63797.0 60003.0 78372.0 124380.0 93692.0 97011.0 80182.0 129493.0 93194.0 102112.0 True False 84083.11893996502 79397.79632738212 77332.7360726449 95706.11265184391 80684.48304164127 90944.88683421229 87318.04266688394 109482.83230311252 98120.04458067824 98537.08996047385 0.8533144115956057 0.805765588969909 0.7848084016248638 0.9712699318625553 0.8188234813307985 0.922950808377769 0.88614391496552 1.111082459884185 0.995767630442883 1.0 16.588379245541077 -7.658413130614831 6.100882886814884 1.0390805669802976 0.8608877780263102 0.6385676551198233 0.059574493391414324 0.12927560732554744 6.567396539073008 0.028832762570746347 0.016347603264662613 2.1957701122699854e-08 7.658413130614831 -0.17819278895398738 HSQPAT(ph)PTPLQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HSQPATPTPLQSR 13 0 Q9NR12-2;Q9NR12 Q9NR12-2 PDLIM7 PDZ and LIM domain protein 7 1 HSQPAT(0.985)PT(0.014)PLQSR;HSQPAT(0.998)PT(0.002)PLQSR;HS(0.013)QPAT(0.985)PT(0.002)PLQSR 102.36 0.0037108 39006000.0 98144.0 87304.0 96486.0 107302.0 135907.0 105853.0 102744.0 96435.0 99162.0 75422.0 True False 114757.84076764148 95970.96414796461 98786.59216519263 101290.21681777747 109276.99896656266 100301.88233644352 93011.34451785624 93903.68343132843 100612.05665392717 89095.41155977645 1.288033118188667 1.0771706698226 1.1087730606521091 1.1368735498776972 1.2265165742373372 1.1257805601935893 1.0439521282805062 1.0539676711446133 1.129261932713829 1.0 16.443063513985628 -7.015718949987875 0.020115179134188324 1.2897864509097295e-05 2.2296660647639817 0.40955662987832575 0.06265167977331113 546.5234991627472 5.2657969449012425 278.69300530195227 303.620593272 9.644529593154829e-08 7.015718949987875 2.2296531668994723 HSQPAT(ph)PTPLQSR ddPTM_PC-9_Lapatinib_30min_R1 4 HSQPATPTPLQSR 13 0 Q9NR12-2;Q9NR12 Q9NR12-2 PDLIM7 PDZ and LIM domain protein 7 1 HS(0.001)QPAT(0.994)PT(0.003)PLQS(0.001)R;HSQPAT(0.985)PT(0.015)PLQSR;HSQPAT(0.995)PT(0.004)PLQSR;HSQPAT(0.999)PT(0.001)PLQSR 115.58 0.0006022 53920000.0 105990.0 88912.0 99339.0 84330.0 96179.0 81701.0 86251.0 68392.0 87300.0 73814.0 True False 104478.56316381469 88706.12972673707 91171.73087962912 90531.90951663342 90521.94031518933 78206.83868433307 90716.65475061577 71569.74199727105 77467.35469024525 86572.65154902733 1.206831040685487 1.0246437892283051 1.053123928265005 1.0457333568599767 1.0456182026944787 0.9033665630541928 1.04786734756809 0.826701512737427 0.8948247894010083 1.0 16.401623726603475 -3.937078498075482 0.34550175435775254 0.9146588467187643 1.535954738404365 0.5374443715996573 0.06897960775926078 9.356459519058859 0.5694444901146006 0.06379662501099208 2.7138025196719706 0.00011559032955242696 3.937078498075482 0.6212958916856007 HSQPATPT(ph)PLQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSQPATPTPLQSR 13 0 Q9NR12-2;Q9NR12 Q9NR12-2 PDLIM7 PDZ and LIM domain protein 7 1 HSQPAT(0.365)PT(0.617)PLQS(0.018)R 75.877 0.037471 6907600.0 26473.0 27077.0 33311.0 32847.0 39767.0 29998.0 33195.0 29603.0 31689.0 24309.0 True False 30954.356034416516 29765.025614341106 34105.260572670995 31006.689081410823 31974.941819798107 28424.852071539106 30050.529289011953 28825.952616971175 32152.391675301944 28716.02927006187 1.0779469453559942 1.036529992862658 1.1876732765496834 1.079769378621476 1.1134875758444027 0.9898601162512976 1.046472303200407 1.0038279438245283 1.1196670463357787 1.0 14.809568652790077 -6.745014438118436 24.99980653760684 1.0331113990340632 1.099455241785075 0.3166769998701062 0.04927881437250163 305.4424919834123 464902.39366628043 0.015982010759737073 0.015936045553304502 1.798811112665975e-07 6.745014438118436 0.06634384275101168 HSQPS(ph)PEPHS(ph)PTEPPAWGSSIVK ddPTM_PC-9_AZD4547_30min_R2 1 HSQPSPEPHSPTEPPAWGSSIVK 23 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 2 HS(0.449)QPS(0.647)PEPHS(0.803)PT(0.1)EPPAWGSS(0.001)IVK 68.834 0.00279 4451000.0 13305.0 10003.0 12910.0 22766.0 15046.0 17852.0 13574.0 16273.0 17584.0 14964.0 True False 17535.713238808006 13236.274130673539 12738.804964755846 17517.65043119376 12957.122612864832 16735.71161790268 14782.059703677662 13758.381766339146 18513.454341552522 14440.114914687121 1.214374909230974 0.9166321881005843 0.8821816889974425 1.2131240322316592 0.8973005193806367 1.1589735758183404 1.023680198600272 0.9527889388432372 1.2820849730719515 1.0 13.817794602812592 -8.238464397940183 24.973279262404084 1.1410426193124723 1.02896868311739 0.0934729196370272 0.13502209354764183 1550.1315903451396 1684963.5119830368 0.08611002183990274 0.03249622912073107 5.774782105733841e-09 8.238464397940183 -0.11207393619508221 HSQPS(ph)PEPHS(ph)PTEPPAWGSSIVK ddPTM_PC-9_Lapatinib_30min_R1 1 HSQPSPEPHSPTEPPAWGSSIVK 23 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 2 HS(0.188)QPS(0.852)PEPHS(0.943)PT(0.017)EPPAWGSSIVK 51.066 0.04637 0.0 9560.0 7848.4 11994.0 8638.4 8548.3 12421.0 8509.1 10148.0 9846.3 8529.5 True False 9423.672646910716 7830.227512004254 11007.899618178884 9273.696752857639 8045.505800604426 11889.782784765202 8949.659562653935 10619.513127095373 8737.306007864385 10003.812710155658 0.9420081043044722 0.7827243211036101 1.1003704224694149 0.9270162308659756 0.8042439451547109 1.18852512829383 0.894624861735809 1.0615465757685236 0.8733975995966475 1.0 13.288262332518938 -6.710559693450167 24.999821912868942 1.0006586346179092 0.9155114384973772 0.13878843156287324 0.11465629713591564 235.30507845316546 115616.54021311013 0.03664209526368349 0.03664205613717394 1.9473333720382075e-07 6.710559693450167 -0.08514719612053201 HSS(ph)ETFSSTPSATR ddPTM_PC-9_AZD4547_30min_R2 2 HSSETFSSTPSATR 14 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 HS(0.02)S(0.961)ET(0.013)FS(0.007)STPSATR;HS(0.01)S(0.988)ET(0.001)FSSTPSATR 177.38 8.8808e-05 39708000.0 20152.5 20219.3 40734.0 52514.0 45729.0 44217.0 31493.0 40264.0 31106.0 46026.0 True False 26560.575801960036 26754.793315038245 40193.84054487721 40407.70863321218 39380.31768999709 41452.104000045 34295.815989974966 34042.12397467458 32750.199655842385 44414.643749224095 0.5980139332407465 0.602386759333303 0.9049682075988593 0.9097834682940148 0.8866516618336053 0.9332981309969226 0.7721736142614923 0.7664617139987593 0.7373739129994602 1.0 15.438747798945727 -5.254409054372979 24.347304699325186 0.857160741359479 0.6002002870379606 0.6415634328771737 0.07869685656492664 249.6997600187615 864747.2619982174 0.02133966589794554 0.05384475416004471 5.566611924989985e-06 5.254409054372979 -0.2569604543215184 HSS(ph)ETFSSTPSATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HSSETFSSTPSATR 14 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 HS(0.055)S(0.944)ET(0.001)FSSTPSATR;HS(0.019)S(0.981)ETFSSTPSATR;HS(0.048)S(0.948)ET(0.003)FS(0.001)STPSATR 149.32 0.00022297 45349900.0 32248.3 37134.0 45505.0 51249.0 59293.0 53264.0 54407.0 50760.0 47627.0 41641.0 True False 37707.30025704201 40820.41810994355 46590.011778673535 48377.684681499755 47674.96228836189 50470.74207408691 49253.17508743101 49427.60378466563 48323.454773568286 49190.183670025384 0.7665614853156035 0.8298488654519489 0.9471404313349556 0.983482497362157 0.9691966715996059 1.026032803875092 1.0012805688595956 1.0048265750791439 0.9823800435007269 1.0 15.586082821464524 -5.14324487675153 1.3516241731940932 0.9991360703638406 0.7325296206673602 0.9698974433501906 0.013938212253323581 0.10924397394037867 0.27619428655941203 0.004303656584416042 0.03337687200440796 7.190434313600608e-06 5.14324487675153 -0.2666064496964804 HSS(ph)ETFSSTPSATR ddPTM_PC-9_Lapatinib_30min_R1 2 HSSETFSSTPSATR 14 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 HS(0.137)S(0.824)ET(0.036)FS(0.002)STPSATR;HS(0.112)S(0.88)ET(0.008)FSSTPSATR 147.52 8.9149e-05 35411000.0 30938.1 22741.9 40769.0 27967.4 32824.0 37712.0 28423.6 31310.4 36736.0 24606.4 True False 30496.91702064731 22689.242527808183 37417.13019289102 30024.21589251142 30893.356854466947 36099.145670965736 29895.23493025707 32765.19548823483 32598.40483277029 28859.58345403296 1.0567344836845018 0.7861943871763504 1.2965235708439233 1.0403551368069281 1.0704713359315579 1.2508547023370529 1.0358858774893158 1.1353315455998407 1.129552160192903 1.0 14.816762856331511 -5.2545020568774605 24.99992857377928 1.1217793428052716 0.9214644509474701 0.35276762342525936 0.10747389928209274 541.5327436006075 1951500.7366775589 0.02551987230936048 0.06440106593681015 5.565419983937677e-06 5.2545020568774605 -0.2003148918578015 HSS(ph)ETFSSTTTVTPVSPSFAHNPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSSETFSSTTTVTPVSPSFAHNPK 24 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 HS(0.259)S(0.297)ET(0.259)FS(0.086)S(0.017)T(0.021)T(0.026)T(0.026)VT(0.009)PVSPSFAHNPK 60.133 0.0024701000000000002 3761200.0 1510.4 1522.2 4933.2 6079.3 9923.9 7561.0 6196.8 5518.8 6809.8 4839.8 True False 1766.080888240195 1673.3139561306643 5050.826197265182 5738.696530356523 7979.383034312225 7164.487849620216 5609.79424305315 5373.937347651948 6909.380442124118 5717.217428164277 0.30890567140932756 0.2926797829810617 0.8834413350074277 1.0037569153984656 1.3956759795427789 1.2531424490393464 0.9812105825148547 0.9399567910744034 1.2085215454789218 1.0 12.481097442271437 -5.385825903301113 2.2460267786771175 1.122990757794077 0.2626877666339288 0.847005725609165 0.13582962927011302 0.12170372436966106 1.1660338642949566 0.04170046556352849 0.12187581627921518 4.1131457274616304e-06 5.385825903301113 -0.8603029911601482 down HSS(ph)NPPLESHVGWVMDSR ddPTM_PC-9_AZD4547_30min_R2 2 HSSNPPLESHVGWVMDSR 18 0 Q6PKG0;Q6PKG0-3;H0YC33;H0YBR8 Q6PKG0 LARP1 La-related protein 1 1 HS(0.214)S(0.786)NPPLESHVGWVMDSR;HS(0.221)S(0.778)NPPLES(0.001)HVGWVMDSR 87.79299999999999 0.0038073 73676000.0 81657.0 61040.0 217058.0 269205.0 203791.0 208585.0 99301.0 223790.0 154200.0 174432.0 True False 107622.22742888724 80769.98629774197 214179.66909682212 207143.9464257891 175498.13733871677 195542.14697626224 108138.59662847308 189208.39768260522 162350.6971944609 168325.1887729687 0.639370899943231 0.47984491736814144 1.2724160338575377 1.230617639200618 1.0426136374361814 1.1616927234818246 0.6424385881683268 1.1240646694761953 0.9645062535081069 1.0 17.360891557217037 -5.251436938785401 24.98521727375246 1.0541598546083424 0.559607851287949 0.5761971143013531 0.16987237308552167 493.3274738742728 1232282.6426875542 0.044759920741863704 0.11547718490321343 5.604837958399109e-06 5.251436938785401 -0.4945520033203934 HSS(ph)NPPLESHVGWVMDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HSSNPPLESHVGWVMDSR 18 0 Q6PKG0;Q6PKG0-3;H0YC33;H0YBR8 Q6PKG0 LARP1 La-related protein 1 1 HS(0.437)S(0.562)NPPLESHVGWVMDSR;HS(0.198)S(0.802)NPPLESHVGWVMDSR 105.95 0.00022922 104961000.0 61539.0 65950.0 161522.0 77173.0 133972.0 110976.0 90788.0 101774.0 100137.0 68705.0 True False 71956.3372493468 72497.0801516342 165373.29705559587 72849.24700824167 107721.148326049 105156.22319791742 82187.90339180037 99102.54033846667 101601.31418440829 81160.6726315194 0.8865911890114374 0.8932538112489642 2.037603825764399 0.8975929430623039 1.327257954294167 1.2956549001921303 1.0126567551373649 1.2210660301992051 1.251854018579814 1.0 16.308493201249938 -7.230471209518234 24.238329556021537 1.1398161866000907 1.2349805430224965 0.020771136390438483 0.32607598162040774 2768.882509581005 2167166.0151276896 0.12538252099666525 0.09710634209576174 5.88205106457672e-08 7.230471209518234 0.09516435642240584 HSS(ph)NPPLESHVGWVMDSR ddPTM_PC-9_Lapatinib_30min_R1 3 HSSNPPLESHVGWVMDSR 18 0 Q6PKG0;Q6PKG0-3;H0YC33;H0YBR8 Q6PKG0 LARP1 La-related protein 1 1 HS(0.248)S(0.751)NPPLESHVGWVMDSR;HS(0.219)S(0.781)NPPLESHVGWVMDSR;HS(0.259)S(0.741)NPPLESHVGWVMDSR 91.774 0.0010390999999999998 58238500.0 84022.0 101256.0 159836.0 106222.0 120009.0 150281.0 71241.0 83678.0 183795.0 85545.0 True False 82823.83087225226 101021.54795314996 146694.90106480266 114033.92022620428 112950.30656677204 143853.83195212125 74929.51039510986 87565.9853615578 163094.07165284787 100331.33926845244 0.8255030928137412 1.0068792930477162 1.4621044843455855 1.1365732886420303 1.1257729378510093 1.4337876181161846 0.7468205940580943 0.8727680304083363 1.6255546157563368 1.0 16.61441278771622 -5.0044432793055185 15.516120961956178 1.166495242528118 0.8708053533600298 0.15438415160658114 0.2577391371012816 2.6477794265998242 9324.70698287422 0.06435850005749948 0.21590623162286812 9.898211302497278e-06 5.0044432793055185 -0.29568988916808825 HSS(ph)PHISR ddPTM_PC-9_AZD4547_30min_R2 2 HSSPHISR 8 0 O60583-2;O60583 O60583-2 CCNT2 Cyclin-T2 1 HS(0.159)S(0.841)PHISR;HS(0.126)S(0.874)PHISR 76.143 0.01438 3124140.0 692.01 1562.44 6631.1 16853.4 9328.0 8793.8 2693.25 10188.599999999999 5830.3 9073.8 True False 912.0547852978217 2067.4681748205103 6543.16728131623 12968.109012434363 8032.968213000349 8243.92229584991 2932.9440324834145 8614.185980736373 6138.477755206641 8756.129023849775 0.10416187139472072 0.23611668685890538 0.7472671158104315 1.4810321978024854 0.9174109005383893 0.9415030629853984 0.33495897839041866 0.9837892928796754 0.7010492580096495 1.0 13.09607749782608 -5.280420228705614 3.817906825546557 0.8991614092263515 0.14570447510640477 0.5386640756871759 0.2692848110730251 0.16937456866891618 5.558338420824993 0.07513430575945229 0.19224502202490024 5.2429989567066614e-06 5.280420228705614 -0.7534569341199466 HSS(ph)PHISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HSSPHISR 8 0 O60583-2;O60583 O60583-2 CCNT2 Cyclin-T2 1 HS(0.147)S(0.853)PHISR;HS(0.344)S(0.656)PHISR 83.86200000000001 0.0081919 1352800.0 1743.4 3355.6 11302.599999999999 9609.2 12684.9 11782.8 7810.4 7372.6 7393.200000000001 4920.4 True False 2038.5231862804271 3688.7217916121795 11572.0968493492 9070.82767744674 10199.384904316557 11164.88922556607 7070.542369600808 7179.07706191541 7501.31156343975 5812.429570135034 0.35071791609391806 0.634626492605653 1.9909225066240859 1.56059141327987 1.754754149060529 1.9208644321356807 1.2164521366297685 1.2351249981251173 1.2905638636866064 1.0 12.504925614577427 -5.119138486863086 5.421234782784571 1.5189390186137453 0.4184153097087799 0.6333993956518384 0.30769156968546574 0.13171090187378612 5.195214647001413 0.08180948990296906 0.23039523528372413 7.600838644319958e-06 5.119138486863086 -1.1005237089049653 HSS(ph)PHISR ddPTM_PC-9_Lapatinib_30min_R1 1 HSSPHISR 8 0 O60583-2;O60583 O60583-2 CCNT2 Cyclin-T2 1 HS(0.481)S(0.519)PHISR 69.672 0.022799 1232000.0 1013.7 417.52 3104.3 1051.4 2145.7 4866.1 1122.6 2622.1 5317.0 1065.7 True False 999.2444521101878 416.5532580923524 2849.0764369445333 1128.7234633675828 2019.4941446085097 4657.988246433132 1180.7227350760145 2743.932338446669 4718.143469507833 1249.9048250440094 0.7994564322727566 0.33326798148625875 2.2794347056338604 0.9030475287011075 1.6157183364240577 3.7266743460000034 0.944650113687209 2.1953130218135244 3.774802188912029 1.0 10.287602528617754 -6.530197682090528 24.976260285928667 2.3559264379524287 1.12981788350099 0.2606299052408555 0.9932203344939953 247.94088344896048 846104.2614520001 0.3209431990115384 0.32157930051542916 2.9498662014203175e-07 6.530197682090528 -1.2261085544514387 HSS(ph)PSGTVAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSSPSGTVAAR 11 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 HS(0.043)S(0.935)PS(0.011)GT(0.011)VAAR 65.232 0.045208 2577200.0 11353.0 11988.0 15118.0 16501.0 18493.0 17600.0 20386.0 22286.0 21250.0 15203.0 True False 13274.83866802895 13178.08941406807 15478.470455334284 15576.502466963806 14869.42940311127 16677.025016970743 18454.890498141216 21701.01611396885 21560.74104894968 17959.18355311822 0.7391671580595914 0.7337799836552138 0.8618693834022754 0.8673279840864084 0.8279568700398698 0.9286070810315397 1.0276018641692055 1.2083520417163365 1.2005412709981536 1.0 14.132434144403502 -7.1893685771039 1.4655071113578886 1.1533720818594995 0.8016903479099668 0.8094876381566205 0.07012165923953785 0.17014138551839456 0.7192783096058577 0.04089151711216122 0.025745367555111455 6.465936316484798e-08 7.1893685771039 -0.3516817339495326 HSS(ph)TSS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 HSSTSSR 7 0 Q9BSF8;E9PKU9;E9PKM7;E9PPD8 Q9BSF8 BTBD10 BTB/POZ domain-containing protein 10 2 HS(0.004)S(0.715)T(0.347)S(0.325)S(0.609)R 53.493 0.036943000000000004 1953700.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HSS(ph)YPAGTEDDEGMGEEPSPFR ddPTM_PC-9_AZD4547_30min_R2 4 HSSYPAGTEDDEGMGEEPSPFR 22 0 Q92934 Q92934 BAD Bcl2-associated agonist of cell death 1 HS(0.189)S(0.81)YPAGTEDDEGMGEEPSPFR;HS(0.209)S(0.791)YPAGTEDDEGMGEEPSPFR;HS(0.22)S(0.75)Y(0.03)PAGTEDDEGMGEEPSPFR;HS(0.13)S(0.456)Y(0.358)PAGT(0.056)EDDEGMGEEPSPFR 171.32 2.0913e-09 80780500.0 69480.4 62434.9 85355.5 117801.0 96629.0 85974.3 68281.5 92915.8 73717.0 83234.0 True False 91573.72191790126 82615.76044398574 84223.63029970703 90643.79945730725 83213.73128795144 80598.3134299268 74358.4212212073 78557.79810267391 77613.53012376171 80320.00299445797 1.1401110371499834 1.0285826365032154 1.0486009357534312 1.128533317703706 1.0360274923507302 1.003465020232731 0.9257771221240864 0.9780601988784083 0.9663038748780549 1.0 16.29347170262411 -6.737355178091311 2.4914262669688174 0.9662829404648013 1.0795150900957708 0.6752721933166129 0.0365950735842486 0.1689960567624611 2.1500873387556263 0.01358605117062851 0.012759650316131731 1.830816517335478e-07 6.737355178091311 0.1132321496309695 HSS(ph)YPAGTEDDEGMGEEPSPFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HSSYPAGTEDDEGMGEEPSPFR 22 0 Q92934 Q92934 BAD Bcl2-associated agonist of cell death 1 HS(0.159)S(0.841)YPAGTEDDEGMGEEPSPFR;HS(0.22)S(0.78)YPAGTEDDEGMGEEPSPFR 241.6 2.1508e-52 55314000.0 64590.0 84205.0 79777.0 115855.0 117952.0 140234.0 149472.0 138127.0 145492.0 129353.0 True False 75523.8112893501 92564.31590854192 81679.18623595747 109364.0199569781 94840.15232551678 132879.882172152 135312.93007643305 134501.3126076542 147619.54525617827 152803.6749422151 0.4942538935526944 0.6057728385364191 0.5345367921736545 0.7157159014554831 0.6206666977177214 0.8696118219827006 0.8855345274097863 0.8802230225059561 0.966073265659368 1.0 17.221319715174047 -6.68480328272572 0.5826424141124004 0.9910118200043357 0.5058748879181229 0.903428935868705 0.054611632399917245 0.24483448488219106 0.18128275225887636 0.04265073568182209 0.053418289279655536 2.066315898729188e-07 6.68480328272572 -0.4851369320862129 HSS(ph)YPAGTEDDEGMGEEPSPFR ddPTM_PC-9_Lapatinib_30min_R1 4 HSSYPAGTEDDEGMGEEPSPFR 22 0 Q92934 Q92934 BAD Bcl2-associated agonist of cell death 1 HS(0.199)S(0.8)YPAGTEDDEGMGEEPSPFR;HS(0.189)S(0.81)Y(0.001)PAGTEDDEGMGEEPSPFR;HS(0.201)S(0.798)YPAGTEDDEGMGEEPSPFR;HS(0.201)S(0.786)Y(0.013)PAGTEDDEGMGEEPSPFR 174.76 5.773399999999999e-13 49747500.0 74067.7 66707.0 86070.0 70371.59999999999 100401.0 119199.0 115409.0 116734.0 131875.0 112103.0 True False 73011.48101564751 66552.54403996601 78993.6568398078 75546.96221677584 94495.61057596076 114101.13663644058 121384.3133194262 122157.88779841842 117021.84879468607 131479.85418214166 0.5553054608237035 0.5061805434296379 0.6008042626087515 0.5745896410268232 0.7187079052054173 0.8678222024674138 0.9232160628294438 0.9290996598550426 0.8900363445229668 1.0 17.00448223594624 -6.579476242294785 1.4011274970729808 0.9359003644534212 0.5439757153856554 0.9660060850404167 0.032410139559629056 0.06532733200674047 0.26567549409648394 0.013409354739911554 0.014198905197428592 2.633441999909484e-07 6.579476242294785 -0.3919246490677658 HSSAS(ph)FENVWLR ddPTM_PC-9_AZD4547_30min_R2 1 HSSASFENVWLR 12 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 HS(0.008)S(0.008)AS(0.984)FENVWLR 77.387 0.01762 22284000.0 17475.0 28838.0 29423.0 32126.0 25145.0 26813.0 19465.0 29583.0 21364.0 20620.0 True False 23031.686497419745 38159.31954217373 29032.83179535334 24719.847041752208 21654.05078429391 25136.378871321136 21197.347291298487 25011.627099711844 22493.257424529565 19898.100076239534 1.1574816896675502 1.9177368389929876 1.459075574256542 1.2423219778289465 1.0882471543175707 1.2632552241174357 1.0652950387263553 1.2569856922962415 1.130422368886813 1.0 14.280343064517236 -5.759339345244995 3.2817053994020786 1.1522667712961605 1.5668966357664953 0.44277633328513333 0.188083888993786 0.19408102771176072 4.341984800386273 0.050398735187262726 0.08700443128466535 1.740446407070131e-06 5.759339345244995 0.4146298644703348 HSSAS(ph)FENVWLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HSSASFENVWLR 12 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 HS(0.008)S(0.008)AS(0.983)FENVWLR;HS(0.005)S(0.005)AS(0.989)FENVWLR 86.463 0.009108499999999999 35213000.0 60565.0 71001.0 68499.0 62913.0 121651.0 78674.0 84405.0 47907.0 59603.0 69985.0 True False 70817.4582867236 78049.51005073804 70132.27594390426 59388.18857669797 97814.35982901049 74548.1969423384 76409.54736071851 46649.49201166226 60474.58111720225 82672.72649904467 0.8566000092853105 0.9440780939000475 0.8483121207417137 0.7183528485344466 1.18315149349938 0.9017266043983664 0.9242412896785431 0.5642670078408666 0.7314937304977001 1.0 16.335123846380682 -7.709269583582199 24.999275043449924 0.7359090140526728 0.9125005847954176 0.16099836932491418 0.14787358418081073 139.86514726961013 67021.70586144523 0.06838197722135492 0.03948029255248636 1.953126697229155e-08 7.709269583582199 0.17659157074274479 HSSLWPIRRPSS(ph)S(ph)LVMNS(ph)TLTWPK ddPTM_PC-9_AZD4547_30min_R2 1 HSSLWPIRRPSSSLVMNSTLTWPK 24 2 H0Y9M1 H0Y9M1 SPATA20 3 HS(0.147)S(0.161)LWPIRRPS(0.438)S(0.471)S(0.783)LVMNS(0.466)T(0.42)LT(0.114)WPK 53.196999999999996 0.025169 0.0 6438.9 7733.3 10251.0 11854.0 14195.0 11225.0 7905.1 13147.0 9019.9 7996.1 True False 8486.336262559997 10232.937992076155 10115.065042115593 9121.243442474342 12224.269273535589 10523.098975518576 8608.638585792123 11115.433238005327 9496.67349950919 7716.158972823422 1.0998135591100657 1.3261699283434822 1.3108938109934232 1.1820963609743755 1.5842427970431774 1.363774257707921 1.115663715083119 1.4405396878361716 1.2307514053244368 1.0 12.913667151602937 -8.545885948538325 20.9037831135187 0.999999987996362 1.3069910827500693 0.29962256872951576 0.1390821738478708 718.4913120545227 652804.8761532017 0.1325428668035992 0.03422242108118938 2.8452081985624773e-09 8.545885948538325 0.3069910947537072 HST(ph)SGTDEGEDGDEPDDGSNDVVDLLPR ddPTM_PC-9_AZD4547_30min_R2 1 HSTSGTDEGEDGDEPDDGSNDVVDLLPR 28 0 Q14008-2;Q14008;Q14008-3 Q14008-2 CKAP5 Cytoskeleton-associated protein 5 1 HS(0.102)T(0.347)S(0.275)GT(0.275)DEGEDGDEPDDGSNDVVDLLPR 125.85 7.0017e-11 2365900.0 503.01 1076.3 3114.1 8396.7 3031.1 4300.9 2421.0 4874.3 3784.8 2261.4 True False 662.9567167420374 1424.1929268063523 3072.804999283206 6460.970542721809 2610.2840855944837 4031.96404310092 2636.464309901549 4121.088935271115 3984.856801177662 2182.22907431659 0.3037979488700818 0.6526321840214542 1.4081037758355037 2.9607205855531893 1.1961549391472333 1.8476355624414054 1.2081519492756332 1.8884767799007163 1.8260488085677267 1.0 11.091586837759916 -5.270579040459575 3.4851467195949644 1.7317954937073046 0.4156629175333001 0.4618772829960528 0.5211169003451912 0.18989466043981892 4.94647572890866 0.13522975868739417 0.3658380537836334 5.3631625440226635e-06 5.270579040459575 -1.3161325761740046 HST(ph)SPASSEYSWK ddPTM_PC-9_AZD4547_30min_R2 2 HSTSPASSEYSWK 13 0 Q96N46 Q96N46 TTC14 Tetratricopeptide repeat protein 14 1 HS(0.092)T(0.454)S(0.454)PASSEYSWK;HS(0.017)T(0.864)S(0.118)PASSEYSWK 113.52 0.00070413 15846900.0 44587.0 42446.0 117401.0 215131.0 170948.0 151012.0 96017.0 167119.0 104049.0 145128.0 True False 58764.7385327871 56165.83942322993 115844.18603154935 165535.8716908173 147214.820977271 141569.1957675737 104562.32699042396 141294.59856257806 109548.8177197566 140047.11289352513 0.4196069259740091 0.4010496058275163 0.8271801084512413 1.1820013156334805 1.051180691523397 1.0108683631001074 0.7466225103113728 1.0089076143254831 0.7822283191446028 1.0 17.095552716634472 -5.342940305277168 3.770589627494739 0.9670872777870962 0.4040282382313076 0.769277071381014 0.1202212813199947 0.1036857116860266 2.7695857004022058 0.03357564052567399 0.07904373393370534 4.540040162028952e-06 5.342940305277168 -0.5630590395557886 down HST(ph)SPASSEYSWK ddPTM_PC-9_Lapatinib_30min_R1 1 HSTSPASSEYSWK 13 0 Q96N46 Q96N46 TTC14 Tetratricopeptide repeat protein 14 1 HS(0.011)T(0.724)S(0.265)PASSEYSWK 161.87 1.2516e-12 0.0 14837.0 10243.0 18274.0 10814.0 18748.0 16417.0 12220.0 13463.0 17879.0 7154.1 True False 14625.421659227439 10219.282962828043 16771.582259679915 11609.297634446482 17645.27949998618 15714.883179896173 12852.69180708079 14088.540129097863 15865.278745783424 8390.676652760954 1.7430562831204965 1.2179331162124316 1.9988354877387895 1.3835949250441488 2.1029626370097336 1.872898197635251 1.5317825175460202 1.6790707963298794 1.8908223260591206 1.0 13.034571443863465 -10.718616956789637 4.5506226219972215 0.9998575836979314 1.7073513687566553 0.4024115489933191 0.26072708452768445 27699303.773758974 65243537.13500725 26223.786848308562 0.06115536155285138 1.9115384723126202e-11 10.718616956789637 0.7074937850587238 HSTENDS(ph)PTNVQQ ddPTM_PC-9_AZD4547_30min_R2 2 HSTENDSPTNVQQ 13 0 B3KVN2;P49354-2;P49354 B3KVN2 FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 1 HS(0.002)T(0.002)ENDS(0.914)PT(0.082)NVQQ;HST(0.006)ENDS(0.994)PT(0.001)NVQQ 183.06 6.0456000000000005e-05 18881700.0 12136.6 10236.0 14581.6 19663.3 19638.2 19557.2 12190.5 16793.5 14610.7 17189.1 True False 15995.786343037735 13544.58682411021 14388.238456551813 15130.229979956608 16911.774910006807 18334.285192339597 13275.430883872283 14198.45045123925 15382.991773664775 16587.314840954852 0.964338501825708 0.8165629551244784 0.8674242090725006 0.9121566766550645 1.019560734944926 1.1053196595190558 0.800336342027742 0.8559824533011585 0.927394935296185 1.0 14.017792740878022 -4.4479716579997355 22.375284039457927 0.9192910380533464 3.1010456107996776 0.01722268542373806 0.09093546750423502 2594.910508146941 827879.6147901671 0.023454112939632066 19443.790767672286 3.564743961389683e-05 4.4479716579997355 2.181754572746331 HSTENDS(ph)PTNVQQ ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSTENDSPTNVQQ 13 0 B3KVN2;P49354-2;P49354 B3KVN2 FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 1 HSTENDS(0.891)PT(0.109)NVQQ 174.72 0.00017548 6086400.0 4391.1 6141.0 8576.8 8846.5 10805.0 8986.7 8091.3 7226.7 7096.9 5604.8 True False 5134.426501821716 6750.637895544876 8781.30343969513 8350.85928573997 8687.8378143415 8515.42163181881 7324.833488060927 7037.006782321575 7200.678736484277 6620.905872427614 0.775487010501651 1.019594301084618 1.3262993929976212 1.2612865137558669 1.3121826501901357 1.2861414730695386 1.1063189281341061 1.062846522501821 1.0875669999283775 1.0 12.692812904753499 -10.829944687247293 14.308549626729103 0.9999987643465954 1.149642385020531 0.057176670087277115 0.16090121015943118 1.1582990962397114e-10 0.0 0.16836694845014366 0.04083498307781566 1.479296782840749e-11 10.829944687247293 0.14964362067393566 HSTENDS(ph)PTNVQQ ddPTM_PC-9_Lapatinib_30min_R1 2 HSTENDSPTNVQQ 13 0 B3KVN2;P49354-2;P49354 B3KVN2 FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 1 HST(0.018)ENDS(0.974)PT(0.008)NVQQ;HS(0.001)T(0.011)ENDS(0.799)PT(0.189)NVQQ 145.52 7.2232e-05 14332300.0 19400.7 19844.8 21310.8 18391.1 21091.3 21611.5 16954.800000000003 18594.5 23981.3 15662.7 True False 19124.042460347344 19798.850584860887 19558.70828606691 19743.6428449111 19850.751201091225 20687.226523867103 17832.63658352647 19458.468352559623 21280.27345971566 18369.97682576412 1.0410488070690236 1.077783100798078 1.0647105585149994 1.0747777763780517 1.080608396481497 1.1261433109078838 0.9707489972723307 1.0592538323330316 1.1584267994214241 1.0 14.165062186000004 -14.522767015497903 0.003353157672098347 0.02603371561249993 2.047778407651101 0.03381183778035424 0.05077526490422749 654043.9473959056 166.33532550686647 52750.977625418665 47658.88717759071 3.0007719012826635e-15 14.522767015497903 2.021744692038601 HSTENDSPT(ph)NVQQ ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSTENDSPTNVQQ 13 0 B3KVN2;P49354-2;P49354 B3KVN2 FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 1 HST(0.001)ENDS(0.035)PT(0.964)NVQQ 167.73 0.00068149 8991900.0 9655.2 10624.0 14199.0 17870.0 20458.0 19770.0 18252.0 15016.0 15477.0 11905.0 True False 11289.63466110748 11678.680508430029 14537.558010007364 16868.80183532168 16449.401758981807 18733.226396904076 16523.038426963285 14621.845910767126 15703.32184539266 14063.282260071848 0.8027738085838435 0.8304377521873306 1.0337243995508836 1.1994925169933621 1.1696701705038357 1.3320664444097112 1.1749062645123123 1.0397178724259228 1.1166185499936365 1.0 13.779645726996494 -5.387187184301292 2.5949332603235025 1.158562980487275 0.8045183124317209 0.6960297494174502 0.08620818050993828 0.15856774448652558 2.037024190067512 0.025265879235926447 0.06729442569781538 4.100273399219586e-06 5.387187184301292 -0.3540446680555541 HSTLSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 HSTLSSPK 8 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;Q9HAU0-3 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 HSTLS(0.002)S(0.998)PK 84.81700000000001 0.0077593 1116500.0 14724.0 11176.0 24557.0 14736.0 21228.0 20502.0 15909.0 19271.0 26814.0 14325.0 True False 14514.033059949097 11150.122658651399 22538.01825276129 15819.734597854958 19979.41077585376 19625.177252496283 16732.690176665154 20166.401012244296 23793.924956062256 16801.057163137317 0.863876178684392 0.663656015831881 1.3414642920334359 0.9415916179705972 1.189175810894208 1.1680918088627947 0.9959307925799952 1.2003054817580632 1.4162159395700276 1.0 14.036264393269622 -5.253285214299805 24.996382558326008 1.1519079566031705 0.7637660714237386 0.5269805841677102 0.14881714612689528 456.3953793188156 1399060.3247076666 0.036803575328509544 0.09390406768705101 5.581035509031326e-06 5.253285214299805 -0.3881418851794318 HSTPS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 2 HSTPSPTR 8 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 HSTPS(0.899)PT(0.101)R;HST(0.107)PS(0.884)PT(0.009)R 84.68700000000001 0.007814699999999999 14353700.0 5826.6 7124.6 27859.0 54019.0 44169.0 36495.0 22805.9 33403.0 27373.0 35355.0 True False 7679.337599191179 9427.487620853415 27489.571457252754 41565.75413523042 38036.89676243701 34212.96188076172 24835.580919117605 28241.333874579133 28819.88089691292 34117.23221122446 0.2250867699831964 0.2763262729662989 0.8057386158132949 1.2183214006895735 1.1148881165665894 1.002805903742267 0.7279482920934829 0.8277732994204561 0.8447309183372522 1.0 15.05821299112045 -5.307881559802829 3.6334692301637634 0.9564787508447595 0.23268887649071127 0.8113597851920747 0.13512000703617907 0.100721274209191 2.74442113630645 0.04137248987040262 0.10313329110239146 4.921737423302122e-06 5.307881559802829 -0.7237898743540483 down HSTPS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HSTPSPTR 8 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 HST(0.003)PS(0.957)PT(0.039)R;HST(0.002)PS(0.799)PT(0.198)R;HS(0.003)T(0.123)PS(0.843)PT(0.031)R 109.83 0.0037717 75582000.0 22274.9 25213.8 54503.0 49570.0 82476.0 76071.0 57045.0 60684.0 64298.0 43356.0 True False 26045.600620671023 27716.85943180091 55802.558223778535 46792.75360810833 66315.41985891986 72081.70284465802 51641.284629964946 59091.109300012795 65238.23661013485 51216.09959409281 0.5085432281468596 0.5411747409792551 1.089551111194237 0.9136336811853852 1.2948158954800335 1.4074032075057081 1.0083017847755273 1.1537604340887426 1.273783773601911 1.0 15.644309766992397 -5.273486438361381 1.4201038078416217 1.1825368939072798 0.40863329568980683 0.7398200381258013 0.14565793463776236 0.2858065134520012 0.9145736191261714 0.04458630287312877 0.24229198475240862 5.3273785977616565e-06 5.273486438361381 -0.7739035982174729 HSTPS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 3 HSTPSPTR 8 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 HST(0.001)PS(0.98)PT(0.019)R;HST(0.002)PS(0.972)PT(0.025)R;HS(0.001)T(0.013)PS(0.903)PT(0.084)R 80.834 0.010619 77664800.0 20607.4 19002.2 52741.0 26731.6 43347.0 50646.0 29502.7 37610.0 65112.0 27592.9 True False 20313.534697065672 18958.20157339169 48404.83856614744 28697.531038003493 40797.41468348094 48479.98864159233 31030.205448180208 39357.49790205531 57778.400900243345 32362.295999771857 0.6276913942449842 0.5858113890783688 1.4957170704602873 0.8867581904017503 1.2606464845315224 1.4980392195267636 0.9588381939402247 1.2161528311320298 1.7853616103335395 1.0 14.98202634547491 -5.248841660463432 24.424933168088284 1.2544634158636436 0.6067512179120909 0.49954402223826244 0.26251122075219696 453.8067043086955 879851.8836218164 0.06528806466411614 0.17004008206260426 5.638431900891018e-06 5.248841660463432 -0.6477121979515528 HSTPSNSSNPSGPPS(ph)PNSPHR ddPTM_PC-9_AZD4547_30min_R2 9 HSTPSNSSNPSGPPSPNSPHR 21 0 Q9Y5S2 Q9Y5S2 CDC42BPB Serine/threonine-protein kinase MRCK beta 1 HSTPSNSSNPSGPPS(0.89)PNS(0.11)PHR;HSTPSNSSNPSGPPS(0.939)PNS(0.061)PHR;HSTPSNSSNPS(0.004)GPPS(0.896)PNS(0.1)PHR;HSTPSNSSNPSGPPS(0.935)PNS(0.065)PHR;HSTPSNSSNPS(0.006)GPPS(0.96)PNS(0.033)PHR;HSTPSNSSNPS(0.001)GPPS(0.949)PNS(0.05)PHR;HSTPSNSSNPSGPPS(0.764)PNS(0.236)PHR;HSTPSNSSNPSGPPS(0.611)PNS(0.389)PHR;HSTPSNSSNPS(0.002)GPPS(0.812)PNS(0.186)PHR 163.53 1.8053e-08 96979590.0 4766.03 2234.84 25138.440000000002 80181.8 43633.72999999999 31931.7 10772.830000000002 48333.25 18335.360000000004 31043.89 True False 6281.52840041759 2957.2083253218507 24805.087860435095 61697.12480646109 37575.93976250423 29935.005751141805 11731.591000262983 40864.456800092856 19304.52969722067 29957.052860124702 0.20968445827255658 0.09871492830518512 0.828021634045741 2.059519175485551 1.2543269839644637 0.9992640427919983 0.39161365622446437 1.3641013684122048 0.6444068375937135 1.0 14.870608079673858 -5.365471543700014 4.450242723391863 1.1106816521849219 0.1576435524608541 0.43766284904863006 0.4209138689879596 0.2030648103629404 6.607079211461904 0.1176352472801813 0.26003929848297846 4.310508008438096e-06 5.365471543700014 -0.9530380997240677 HSTPSNSSNPSGPPS(ph)PNSPHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 HSTPSNSSNPSGPPSPNSPHR 21 0 Q9Y5S2 Q9Y5S2 CDC42BPB Serine/threonine-protein kinase MRCK beta 1 HSTPSNSSNPS(0.001)GPPS(0.901)PNS(0.098)PHR;HSTPSNSSNPS(0.002)GPPS(0.876)PNS(0.122)PHR;HSTPSNSSNPSGPPS(0.949)PNS(0.051)PHR;HSTPSNS(0.001)S(0.002)NPS(0.114)GPPS(0.827)PNS(0.057)PHR;HSTPSNSSNPSGPPS(0.9)PNS(0.1)PHR;HSTPSNSSNPS(0.002)GPPS(0.953)PNS(0.045)PHR;HSTPSNSSNPSGPPS(0.876)PNS(0.124)PHR;HSTPSNSSNPS(0.002)GPPS(0.871)PNS(0.128)PHR 122.16 8.403499999999999e-07 34154800.0 7283.200000000001 9057.900000000001 41573.50000000001 29577.099999999995 53172.1 49168.50000000001 32440.1 24637.73 35658.100000000006 18789.76 True False 8516.101910242976 9957.10845042435 42564.76990837673 27919.990977251968 42753.40870411363 46590.01730380264 29367.13888201466 23991.01569333274 36179.53225400246 22196.19474834167 0.38367395883833805 0.4485952913694033 1.9176606797233495 1.2578728603621545 1.926159379517421 2.099009214508874 1.3230708783634524 1.0808616506270818 1.6299880526460742 1.0 14.438024745843336 -5.2478410766171235 23.58041006657118 1.5496729135939102 0.41613402357553175 0.613710139030972 0.3529738759315479 239.59804543649068 415475.2813933697 0.09193587108192483 0.23989750699377083 5.651437426346209e-06 5.2478410766171235 -1.1335388900183785 HSTPSNSSNPSGPPS(ph)PNSPHR ddPTM_PC-9_Lapatinib_30min_R1 2 HSTPSNSSNPSGPPSPNSPHR 21 0 Q9Y5S2 Q9Y5S2 CDC42BPB Serine/threonine-protein kinase MRCK beta 1 HSTPSNSSNPSGPPS(0.985)PNS(0.015)PHR;HSTPSNSSNPSGPPS(0.958)PNS(0.042)PHR 182.35 9.979199999999999e-14 4589340.0 2950.15 1787.45 6103.1 1700.6599999999999 3318.22 5262.3 1378.1799999999998 1611.47 7232.5 1169.4 True False 2908.0803200087494 1783.3112693456003 5601.326676647287 1825.7322096354505 3123.048823471524 5037.243696020441 1449.5354169134694 1686.3447791604644 6417.899688398606 1371.5292318724453 2.1203196056117353 1.300235698885528 4.084000943239262 1.3311653643305263 2.277055968546774 3.672720623783915 1.0568753353762121 1.2295361556809294 4.679375064895067 1.0 10.421569655829677 -1.5306456308923795 24.816640755768717 2.2834682101417823 0.019092929780190726 0.0 1.3067206670151015 0.0 0.0 0.28323168576594354 0.0 0.029468251593327194 1.5306456308923795 -2.2643752803615915 HSTPSNSSNPSGPPSPNS(ph)PHR ddPTM_PC-9_Lapatinib_30min_R1 1 HSTPSNSSNPSGPPSPNSPHR 21 0 Q9Y5S2 Q9Y5S2 CDC42BPB Serine/threonine-protein kinase MRCK beta 1 HSTPSNSSNPSGPPS(0.133)PNS(0.867)PHR 170.22 5.5944e-09 5245400.0 2174.4 0.0 14794.0 1738.2 8651.9 12059.0 3108.3 6637.0 17745.0 1194.0 True False 2143.392657263876 0.0 13577.694426491451 1866.03302646522 8143.012252289865 11543.264680901992 3269.232564971293 6945.379249559716 15746.371236865985 1400.3813090950068 1.5305778814264799 0.0 9.695712402264212 1.3325178037909828 5.814853568384362 8.242943979566393 2.3345302766744487 4.959634354194681 11.244345475477704 1.0 10.451603996002799 -6.309088395074559 22.290611084324745 5.766305411293757 3.3837229945509684 0.0977896748221262 3.6086406148528902 305.20589381528714 142776.22808470973 1.1110305219361558 1.259784537041058 4.90807968315198e-07 6.309088395074559 -2.382582416742789 HSTS(ph)GTDEGEDGDEPDDGSNDVVDLLPR ddPTM_PC-9_Lapatinib_30min_R1 1 HSTSGTDEGEDGDEPDDGSNDVVDLLPR 28 0 Q14008-2;Q14008;Q14008-3 Q14008-2 CKAP5 Cytoskeleton-associated protein 5 1 HS(0.064)T(0.253)S(0.542)GT(0.141)DEGEDGDEPDDGSNDVVDLLPR 133.47 3.726699999999999e-11 1783300.0 1239.2 541.5 1853.9 585.72 1320.2 1101.0 484.43 1134.0 692.49 1221.5 True False 1221.5287807585528 540.2461900196606 1701.4794982609496 628.795802704642 1242.5484316130648 1053.9127965563555 509.5114150658059 1186.6897798705313 614.4944839570202 1432.6346474535596 0.8526450082229705 0.3770997657915943 1.1876576496912516 0.43890869442694047 0.8673170328678257 0.7356465924020724 0.3556464420090903 0.8283268745313512 0.4289261641474713 1.0 10.48445502300525 -10.881562369551993 5.314992961217077 1.0001261927167635 0.6766801684051488 0.12514246913570137 0.2579934455642318 0.0003556948783891686 4.291885965931976e-05 0.23031307010302204 0.05583746570066185 1.3135228448213903e-11 10.881562369551993 -0.32344602431161473 HSTS(ph)PASSEYSWK ddPTM_PC-9_AZD4547_30min_R2 1 HSTSPASSEYSWK 13 0 Q96N46 Q96N46 TTC14 Tetratricopeptide repeat protein 14 1 HS(0.072)T(0.362)S(0.566)PASSEYSWK 118.52 0.00013715 3333700.0 10860.0 9108.7 28871.0 51422.0 38406.0 28137.0 22304.0 38556.0 25378.0 29781.0 True False 14313.254097967289 12052.909144663206 28488.15167602371 39567.45236198037 33073.98983581597 26377.588942019276 24289.012791426725 32598.056128739147 26719.42926978616 28738.376254630904 0.4980536816397499 0.4194011880793369 0.9912930161262373 1.3768158650092304 1.1508649459792086 0.917852446091793 0.8451769361016975 1.1343040344350106 0.9297473536098125 1.0 14.810690930016616 -5.291872824183922 5.7475245462304585 1.0545583413083024 0.45620496818399947 0.7264286885706374 0.14355730146494797 0.08873153531297545 9.322658247490018 0.04085064723966819 0.09117843472941635 5.1065451464701925e-06 5.291872824183922 -0.5983533731243029 down HSTS(ph)PASSEYSWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HSTSPASSEYSWK 13 0 Q96N46 Q96N46 TTC14 Tetratricopeptide repeat protein 14 1 HS(0.001)T(0.199)S(0.8)PASSEYSWK;HS(0.027)T(0.126)S(0.847)PASSEYSWK;HS(0.013)T(0.011)S(0.976)PASSEYSWK 104.09 0.0014165999999999998 9465000.0 35643.8 40809.1 68265.0 79570.0 89760.0 86284.0 79638.0 68812.0 71349.0 52882.0 True False 41677.5913428601 44860.35775005379 69892.69649645413 75111.95086942054 72172.1723475513 81759.11514569908 72094.11211080989 67005.7579123407 72392.34414595351 62469.08798631832 0.6671714392883105 0.7181209010107349 1.1188365117762193 1.2023859046232785 1.1553261728962347 1.3087931612448955 1.1540765910749264 1.0726226374077366 1.1588506648569694 1.0 15.930854847067405 -5.2612282632231375 3.951509586603191 1.16066994387058 0.6769441013746688 0.8518956382589133 0.0758156331935386 0.06960873613533314 2.5638857355763034 0.020111691407477924 0.05281446507641026 5.4798886873580815e-06 5.2612282632231375 -0.48372584249591133 HSTS(ph)PASSEYSWK ddPTM_PC-9_Lapatinib_30min_R1 2 HSTSPASSEYSWK 13 0 Q96N46 Q96N46 TTC14 Tetratricopeptide repeat protein 14 1 HS(0.12)T(0.215)S(0.665)PASSEYSWK;HS(0.005)T(0.06)S(0.926)PAS(0.001)S(0.007)EYSWK 102.33 0.0014492 17183300.0 56234.0 36292.0 79379.0 45449.0 67784.0 71496.0 51359.0 44672.0 90917.0 42215.0 True False 55432.09284794739 36207.96810377384 72852.76503180117 48791.4710734195 63797.0783884715 68438.28274531629 54018.117718483016 46747.62420315382 80676.97006154673 49511.80650204831 1.119573224330931 0.7312996770230129 1.4714220744255664 0.9854512392190939 1.2885225342329654 1.3822618801534738 1.0910148817989156 0.9441712493608946 1.6294491306474368 1.0 15.59548496839709 -5.25410615026712 24.989220025663116 1.2167250278252113 0.9254364780437387 0.2104251023491237 0.231018021106677 845.06185200482 2879673.7859369935 0.055724215360333014 0.14124032651142476 5.570495782206369e-06 5.25410615026712 -0.29128854978147256 HSTSGT(ph)DEGEDGDEPDDGSNDVVDLLPR ddPTM_PC-9_AZD4547_30min_R2 2 HSTSGTDEGEDGDEPDDGSNDVVDLLPR 28 0 Q14008-2;Q14008;Q14008-3 Q14008-2 CKAP5 Cytoskeleton-associated protein 5 1 HS(0.006)T(0.02)S(0.08)GT(0.894)DEGEDGDEPDDGSNDVVDLLPR;HS(0.003)T(0.011)S(0.195)GT(0.791)DEGEDGDEPDDGSNDVVDLLPR 114.14 5.3498e-10 2466700.0 1475.07 1242.46 3462.4 5700.0 4267.2 3427.3900000000003 1694.66 4869.4 3011.31 3022.19 True False 1944.1115766379946 1644.0608973704543 3416.486313708028 4385.953064122131 3674.7729372336057 3213.0747614879824 1845.4814570085734 4116.946117680317 3170.481698888793 2916.3840479830415 0.6666171343182781 0.5637326464281958 1.1714802500277202 1.5039010610263888 1.2600442454672809 1.1017323879926346 0.6327978162837986 1.4116611701149508 1.0871276370756053 1.0 11.50996500008745 -5.263870463062322 24.85780142420715 1.1577275275997125 0.6151748555915405 0.4692812534586315 0.22556991442256408 160.74590150317113 1643645.626549154 0.061509222474337495 0.13846364569080233 5.44665085774811e-06 5.263870463062322 -0.542552672008172 HSTSGT(ph)DEGEDGDEPDDGSNDVVDLLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HSTSGTDEGEDGDEPDDGSNDVVDLLPR 28 0 Q14008-2;Q14008;Q14008-3 Q14008-2 CKAP5 Cytoskeleton-associated protein 5 1 HS(0.022)T(0.067)S(0.214)GT(0.697)DEGEDGDEPDDGSNDVVDLLPR;HS(0.065)T(0.065)S(0.221)GT(0.649)DEGEDGDEPDDGSNDVVDLLPR 98.583 2.767e-09 1947400.0 1061.2 1573.13 3294.25 4068.06 4340.360000000001 5973.9 3894.7 2325.77 996.71 3234.9300000000003 True False 1240.840200344608 1729.29994994602 3372.797413512694 3840.139787028468 3489.8976155349637 5660.618167550088 3525.7658208138228 2264.72100185701 1011.2849981599358 3821.3972013082107 0.3247085123524508 0.4525308045324402 0.8826084376567964 1.0049046421329457 0.9132517327275579 1.4812954187573701 0.9226378821879123 0.5926421365153325 0.2646374990314365 1.0 11.899884505868439 -5.206657975603502 3.585844761309872 0.8988064247782512 0.3528148696513586 0.3150740395000705 0.2931280724719815 0.3022870205797286 7.843060009425046 0.08435254132471141 0.25303262971036194 6.21358186189301e-06 5.206657975603502 -0.5459915551268926 HSTSSLS(ph)PQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HSTSSLSPQR 10 0 Q03164-2;Q03164;Q03164-3 Q03164-2 KMT2A Histone-lysine N-methyltransferase 2A;MLL cleavage product N320;MLL cleavage product C180 1 HSTS(0.002)S(0.016)LS(0.982)PQR;HSTS(0.002)S(0.042)LS(0.956)PQR 70.54 0.033083 0.0 5909.21 6580.1 10200.5 7415.2 10562.9 7905.87 5661.360000000001 8484.1 6220.530000000001 7006.9 True False 6909.522540782474 7233.328841634075 10443.718605611679 6999.750384402762 8493.175571412103 7491.272259711277 5125.07499610305 8261.401364647001 6311.493483163434 8277.195503410117 0.83476614004536 0.8738864315400089 1.2617460347902834 0.8456669147803672 1.026093387296821 0.905049573448513 0.6191801309986665 0.998091849013762 0.7625159367763109 1.0 13.014926318245658 -7.001301817999821 24.8557839547069 0.8329775285183109 0.9719459739816266 0.12318839616174082 0.15399019677194564 88.35103735892974 1686935.6230966602 0.05351873280080787 0.0465677820818537 9.970069414373824e-08 7.001301817999821 0.13896844546331577 HSVTAAT(ph)PPPS(ph)PTSGESGDLLSNLLQSPSSAK ddPTM_PC-9_Lapatinib_30min_R1 2 HSVTAATPPPSPTSGESGDLLSNLLQSPSSAK 32 0 Q96QU8-2;Q96QU8 Q96QU8-2 XPO6 Exportin-6 2 HS(0.001)VT(0.007)AAT(0.875)PPPS(0.361)PT(0.361)S(0.361)GES(0.033)GDLLSNLLQSPSSAK;HS(0.006)VT(0.017)AAT(0.879)PPPS(0.241)PT(0.274)S(0.272)GES(0.272)GDLLS(0.037)NLLQS(0.001)PSSAK 98.72200000000001 3.3428e-12 3695500.0 19891.1 39524.0 39243.1 31393.2 39725.0 42838.0 35623.8 36879.0 49659.0 29994.2 True False 19607.44926641901 39432.48460634731 36016.68380074671 33701.96065264524 37388.453602354944 41005.91860025537 37468.22605540793 38592.5329734086 44065.880487547365 35178.657505240735 0.5573677524077773 1.1209206775577738 1.0238220089945482 0.9580229332976818 1.0628163850989767 1.165647625812512 1.0650840228859249 1.097043938292963 1.2526311011437163 1.0 15.102412807001517 -4.758826455697211 24.998229602473 1.0815751169106005 0.5573670579966071 0.7952388524345368 0.07999665125267576 31.816799313509964 304334.9824054827 0.02050165781378779 0.13630213672071265 1.7425030394168238e-05 4.758826455697211 -0.5242080589139934 HSVTAAT(ph)PPPSPT(ph)SGESGDLLSNLLQSPSSAK ddPTM_PC-9_AZD4547_30min_R2 2 HSVTAATPPPSPTSGESGDLLSNLLQSPSSAK 32 0 Q96QU8-2;Q96QU8 Q96QU8-2 XPO6 Exportin-6 2 HS(0.001)VT(0.015)AAT(0.668)PPPS(0.216)PT(0.318)S(0.313)GES(0.313)GDLLS(0.156)NLLQSPSSAK;HS(0.001)VT(0.013)AAT(0.938)PPPS(0.065)PT(0.487)S(0.487)GES(0.009)GDLLSNLLQSPSSAK 106.37 1.5877000000000001e-15 6740100.0 62820.0 58729.0 84698.0 66506.0 70388.0 69412.0 86701.0 101245.0 73672.0 73487.0 True False 82795.45326282727 77712.00074180998 83574.84917930997 51174.06920745731 60615.84118532043 65071.65666714431 94417.22103790741 85599.91162864912 77566.15151563108 70914.242497702 1.1675433643038673 1.0958588571869505 1.1785340466975762 0.7216331642986333 0.8547766859003635 0.9176105444439173 1.3314281830052268 1.2070905450540914 1.093802158545861 1.0 16.113787788640003 -7.243811084377966 24.971714139527574 1.1753377825818703 0.9844851221685614 0.2206361164991728 0.15385737797133384 1222.206607921436 1731343.1271940637 0.06376885359132813 0.04928380054340733 5.70412344437551e-08 7.243811084377966 -0.19085266041330884 HSVTAAT(ph)PPPSPT(ph)SGESGDLLSNLLQSPSSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSVTAATPPPSPTSGESGDLLSNLLQSPSSAK 32 0 Q96QU8-2;Q96QU8 Q96QU8-2 XPO6 Exportin-6 2 HS(0.001)VT(0.021)AAT(0.96)PPPS(0.102)PT(0.393)S(0.393)GES(0.125)GDLLS(0.005)NLLQSPSSAK 81.847 1.4327999999999999e-05 0.0 16294.0 20005.0 20657.0 21690.0 22853.0 18576.0 17591.0 13478.0 17701.0 14851.0 True False 19052.252378830606 21990.96419156085 21149.541222108743 20474.779619928788 18375.118701633142 17601.841858820935 15924.653132188849 13124.216781121428 17959.843637998034 17543.368739548692 1.0860087741233175 1.2535200347231927 1.2055575833865086 1.1670950958108577 1.0474110744881857 1.0033330610637183 0.9077306285131709 0.7481012897787983 1.0237397334931726 1.0 14.098638185324557 -6.633635472450649 1.4831373252416646 0.902627314042291 1.1900263765091543 0.6635333501971656 0.08142595958801475 0.21689976023534482 0.9889422917318245 0.034186400698029834 0.0344795152755681 2.324687217163235e-07 6.633635472450649 0.2873990624668633 HSVTAAT(ph)PPPSPTSGES(ph)GDLLSNLLQSPSSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSVTAATPPPSPTSGESGDLLSNLLQSPSSAK 32 0 Q96QU8-2;Q96QU8 Q96QU8-2 XPO6 Exportin-6 2 HS(0.015)VT(0.107)AAT(0.861)PPPS(0.215)PT(0.215)S(0.215)GES(0.246)GDLLS(0.122)NLLQS(0.002)PSSAK 57.328 0.006231100000000001 9287200.0 26813.0 29658.0 32256.0 30593.0 39734.0 27438.0 34997.0 17520.0 28069.0 23722.0 True False 31351.91131911041 32602.25023710633 33025.1053715612 28878.97339384421 31948.40793290562 25999.10297816156 31681.83080366174 17060.11856397443 28479.4560236691 28022.61081675131 1.1188076487280378 1.1634265789973222 1.1785163626445365 1.0305596999042284 1.1400939099438785 0.9277901744479805 1.1305809801534634 0.6087983263064218 1.0163027353127532 1.0 14.774303754908118 -6.99404790925723 1.1449269346041182 0.885676820255072 1.1372933197270156 0.32519252859743975 0.1321788760287835 0.5026942403282715 1.3544715013256552 0.0742894997002597 0.053684061933550985 1.0137995421278151e-07 6.99404790925723 0.25161649947194364 HSVTAATPPPS(ph)PT(ph)SGESGDLLSNLLQSPSSAK ddPTM_PC-9_AZD4547_30min_R2 1 HSVTAATPPPSPTSGESGDLLSNLLQSPSSAK 32 0 Q96QU8-2;Q96QU8 Q96QU8-2 XPO6 Exportin-6 2 HSVT(0.001)AAT(0.445)PPPS(0.554)PT(0.493)S(0.493)GES(0.009)GDLLS(0.006)NLLQSPSSAK 105.75 8.3051e-15 5121400.0 28053.0 21222.0 36921.0 23283.0 32394.0 29725.0 33695.0 40798.0 32933.0 32319.0 True False 36973.270461351414 28081.596481171033 36431.40341624717 17915.464068764126 27896.652261142088 27866.291050983484 36693.78972413573 34493.606544773815 34673.771145947976 31187.521647138004 1.1855148632736694 0.900411286247492 1.1681403809010384 0.5744433389566298 0.8944812151722255 0.8935077101113835 1.1765535632903688 1.1060066566058544 1.1117834734755172 1.0 14.928681291368736 -7.254375755155544 24.796754129863395 1.1074198130288877 0.9266805680151832 0.18888593899331352 0.16387066630794012 798.7861416341635 2804133.005114451 0.06417109726415411 0.04864625130322663 5.567038757324015e-08 7.254375755155544 -0.18073924501370453 HSVTAATPPPS(ph)PT(ph)SGESGDLLSNLLQSPSSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSVTAATPPPSPTSGESGDLLSNLLQSPSSAK 32 0 Q96QU8-2;Q96QU8 Q96QU8-2 XPO6 Exportin-6 2 HSVT(0.001)AAT(0.192)PPPS(0.586)PT(0.586)S(0.584)GES(0.05)GDLLSNLLQSPSSAK 106.37 6.1429e-08 0.0 37491.0 43384.0 43311.0 46062.0 51477.0 38346.0 46583.0 35608.0 35764.0 30763.0 True False 43837.48581899706 47690.876805132524 44343.69849788219 43481.295475018895 41390.45138073646 36335.068255725 42170.321008285675 34673.32772979461 36286.98084115932 36340.088380226 1.2063120309539663 1.3123489493515628 1.2202419001823688 1.1965104492887995 1.1389749784774477 0.9998618571191 1.1604352902793742 0.9541343809351236 0.9985385963151487 1.0 15.149274307804987 -6.47851477121159 0.7476861772315903 0.9968588143542951 1.2749393073370248 0.75797256379443 0.05682686240107799 0.3276472689338745 0.40698324337762354 0.035311786923280006 0.0478100331209741 3.322654840146784e-07 6.47851477121159 0.27808049298272963 HSVTAATPPPS(ph)PTSGES(ph)GDLLSNLLQSPSSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSVTAATPPPSPTSGESGDLLSNLLQSPSSAK 32 0 Q96QU8-2;Q96QU8 Q96QU8-2 XPO6 Exportin-6 2 HS(0.002)VT(0.02)AAT(0.238)PPPS(0.352)PT(0.354)S(0.251)GES(0.761)GDLLS(0.021)NLLQS(0.001)PSSAK 70.109 7.5103e-05 7582100.0 14126.0 17949.0 18345.0 17088.0 20480.0 16860.0 18449.0 13775.0 13779.0 11968.0 True False 16517.25279878244 19730.858099191508 18782.414373799922 16130.614760043485 16467.091016910115 15975.83191966629 16701.3771608068 13413.420845818931 13980.491807693059 14137.703661364134 1.168312280014837 1.3956197252254257 1.328533602322488 1.1409642715970647 1.1647641944788947 1.1300160409590023 1.1813359199520312 0.948769415960773 0.9888799583414167 1.0 13.787260186726435 -6.924272440247063 0.5870499038431388 0.9677190529807373 1.3084693326525212 0.6645569021389199 0.0783266098516412 0.5104482998002595 0.37665276256236546 0.06924186064537913 0.0686500946660655 1.1904949561849865e-07 6.924272440247063 0.34075027967178384 HSVTAATPPPS(ph)PTSGESGDLLSNLLQSPSSAK ddPTM_PC-9_AZD4547_30min_R2 1 HSVTAATPPPSPTSGESGDLLSNLLQSPSSAK 32 0 Q96QU8-2;Q96QU8 Q96QU8-2 XPO6 Exportin-6 1 HSVTAAT(0.001)PPPS(0.34)PT(0.304)S(0.272)GES(0.076)GDLLS(0.007)NLLQSPSSAK 75.26100000000001 4.1832999999999996e-07 9138800.0 64159.0 54559.0 90357.0 89172.0 78984.0 94923.0 106100.0 126420.0 93029.0 97826.0 True False 84560.22740989718 72194.1297906045 89158.80714178497 68614.77309366643 68018.43496308099 88987.44980428932 115542.69445706475 106884.69384259782 97946.32301753231 94401.14151591709 0.8957542891114233 0.7647590763341751 0.944467468401871 0.7268426206699758 0.7205255558441772 0.9426522643191242 1.2239544204831778 1.1322394213270808 1.0375544346676937 1.0 16.52651668457508 -7.018981432230189 5.466091026708638 1.1078060719496472 0.8116268294710736 0.7148524078087533 0.08560369740470361 0.09358812301671846 8.824879486775414 0.03230659073362827 0.026214186794440646 9.572349959205488e-08 7.018981432230189 -0.29617924247857363 HSVTAATPPPSPTS(ph)GES(ph)GDLLSNLLQSPSSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSVTAATPPPSPTSGESGDLLSNLLQSPSSAK 32 0 Q96QU8-2;Q96QU8 Q96QU8-2 XPO6 Exportin-6 2 HS(0.014)VT(0.055)AAT(0.217)PPPS(0.335)PT(0.316)S(0.507)GES(0.494)GDLLS(0.06)NLLQS(0.001)PSSAK 72.07300000000001 3.8234e-05 2346700.0 7491.4 8188.5 8469.8 8563.0 8466.0 8143.0 10143.0 9490.6 7826.1 7394.0 True False 8759.546058105527 9001.400164088782 8671.75215389537 8083.242871620569 6807.148073689507 7715.966745067768 9182.18161103926 9241.481806121901 7940.54190697341 8734.473669128209 1.0028705094235886 1.03056011215696 0.9928190847429621 0.9254413234068815 0.779342674962684 0.8833922955586517 1.051257575312576 1.0580467874997095 0.9091036515501865 1.0 13.092505055026042 -10.067715836660565 15.425749640744364 1.0000092500478597 0.9593929969985643 0.021511470400771504 0.08253483289680576 0.0 0.0 0.08932388522015806 0.021664224332544706 8.556263748922437e-11 10.067715836660565 -0.04061625304929539 HSVVAGGGGGEGR ddPTM_PC-9_AZD4547_30min_R2 1 HSVVAGGGGGEGR 13 0 Q6PKG0;Q6PKG0-3 Q6PKG0 LARP1 La-related protein 1 0 79.88600000000001 0.011225 1600600.0 3655.2 3430.0 4835.6 6327.9 4822.2 5888.4 3375.9 5438.3 4415.0 3486.3 False True 4817.477567116949 4538.680422694218 4771.4767844750895 4869.100420080427 4152.720767230948 5520.197417144197 3676.348560015132 4597.935694701786 4648.367886598863 3364.2456981471314 1.4319636552616206 1.3490930300346107 1.4182902238986275 1.447308210206555 1.2343690502504236 1.6408425282922894 1.0927705316053142 1.3667062715526732 1.3816969102937298 1.0 11.716067357245139 -13.155778824914298 0.23634996654826532 3.2981467948831216e-10 1.4165722077659797 0.4250234910042723 0.1328353699865723 76.6785554129487 1.3698477895885197 37.25160442839042 0.2109176694810482 6.985880865667309e-14 13.155778824914298 1.416572207436165 HSVVAGGGGGEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HSVVAGGGGGEGR 13 0 Q6PKG0;Q6PKG0-3 Q6PKG0 LARP1 La-related protein 1 0 ; 104.81 0.0010900999999999999 1213840.0 5515.7 7045.5 4160.9 4362.2300000000005 6417.5 5352.4 5931.429999999999 5578.41 6885.6 4438.6900000000005 False True 6449.399069959243 7744.930677912629 4260.111636301123 4117.828395640477 5160.036943409216 5071.710721638309 5369.562010565569 5431.982648313965 6986.288873724604 5243.389360349291 1.2300057513809377 1.4770847910857219 0.8124728765169051 0.7853371383745886 0.9841033325561538 0.9672580792856579 1.0240631853835613 1.0359678206220626 1.3323994068712854 1.0 12.356283965246146 -5.256631398614716 24.998493344118977 0.9864833944375332 1.3535452842802163 0.4800226439263632 0.15011341662814096 342.32408329871623 1779856.5735350016 0.040382769863577674 0.0998697509436045 5.538199567645457e-06 5.256631398614716 0.36706188984268306 HSVVAGGGGGEGR ddPTM_PC-9_Lapatinib_30min_R1 1 HSVVAGGGGGEGR 13 0 Q6PKG0;Q6PKG0-3 Q6PKG0 LARP1 La-related protein 1 0 81.789 0.0094341 1468800.0 4228.7 3528.2 3739.0 4032.1 3052.6 2514.5 2703.3 2689.0 2835.5 2819.2 False True 4168.397962551396 3520.0306696719613 3431.5938529573814 4328.634084691296 2873.05206964251 2406.96069658579 2843.263646651512 2813.9407566771256 2516.136130861287 3306.4949636521274 1.260669684476782 1.0645806838864733 1.0378342899899895 1.3091307055584274 0.8689116727004278 0.7279493007082117 0.859902609230361 0.8510343392657219 0.760967779633977 1.0 11.691086988771044 -6.37212322295378 6.493596259203513 0.8289322431396604 1.1503930935874846 0.7066943857873601 0.10168872732317462 0.1322521078029263 6.791024784554259 0.03074428861890275 0.03487373249288315 4.244991031599932e-07 6.37212322295378 0.32146085044782424 HSYHSSSEAQVS(ph)KR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HSYHSSSEAQVSKR 14 1 Q15256 Q15256 PTPRR Receptor-type tyrosine-protein phosphatase R 1 HSYHSSSEAQVS(1)KR 54.858999999999995 0.035233 10100000.0 3761.4 7756.0 89948.0 22215.0 58018.0 42469.0 17719.0 16831.0 38930.0 15643.0 True False 4398.1307289636325 8525.964422381709 92092.70144968978 20970.365572001756 46649.78938569781 40241.85087759835 16040.528045549105 16389.20408391859 39499.27760167581 18478.95207008013 0.23800758356231622 0.46138787470456044 4.983653894465155 1.1348243933137072 2.5244824061874156 2.177712822944935 0.8680431652572358 0.8869119862297214 2.137528007642293 1.0 14.17359532428147 -7.254185461693113 24.027144228282214 1.2136967830371417 1.9847525419453438 0.06447803494341331 1.2861369533576 989.4724597096842 3277436.6136325025 0.5110631294995138 0.3870369447191374 5.569478583868768e-08 7.254185461693113 0.7710557589082021 HT(ph)GPNSPDTANDGFVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HTGPNSPDTANDGFVR 16 0 P31943;G8JLB6;E9PCY7;P55795;D6RBM0;E5RGV0;D6RIU0;D6RIH9;D6RJ04;D6RDU3;D6RIT2;D6RFM3;D6R9T0;D6RAM1;H0YAQ2;E5RGH4;E7EQJ0 P31943;E7EQJ0 HNRNPH1;HNRNPH2 Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;Heterogeneous nuclear ribonucleoprotein H2 1 HT(0.747)GPNS(0.222)PDT(0.032)ANDGFVR 154.47 8.6324e-05 275150000.0 124090.0 124140.0 140010.0 174470.0 220110.0 164370.0 159110.0 214550.0 145770.0 106390.0 True False 145095.98611078222 136463.79878732128 143348.36939088165 164695.0115393717 176981.02557285604 155750.1478431523 144037.9489433558 208918.2898345152 147901.6104802539 125677.66481722318 1.154508928231597 1.0858237936373556 1.1406033808740599 1.3104556945650816 1.4082138288473525 1.2392826368127101 1.1460902711140801 1.662334275054771 1.1768328978371112 1.0 16.93936875410334 -5.732014128949853 5.631371428029993 1.3038626557607256 1.120158850072416 0.13307959884150178 0.16718603225697282 0.29073645014299654 25.287501219726344 0.04451910612589258 0.07559546061456462 1.8534713232487765e-06 5.732014128949853 -0.18370380568830957 HT(ph)PYGNQTDYR ddPTM_PC-9_Lapatinib_30min_R1 1 HTPYGNQTDYR 11 0 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 HT(0.994)PY(0.006)GNQTDYR 91.12299999999999 0.01754 1225100.0 15713.0 15675.0 16275.0 16819.0 15758.0 13893.0 16409.0 147910.0 19967.0 11457.0 True False 15488.929738588713 15638.705500569122 14936.93232331677 18055.925366539243 14831.145421419998 13298.828776164799 17258.577730146364 154782.43857200223 17718.106198168673 13437.327184507114 1.152679362935141 1.1638256095006854 1.111599957210141 1.3437140525503652 1.103727342333371 0.989693009149766 1.2843757908972442 11.518841243254263 1.3185736980935603 1.0 13.713958580081664 -7.58183527591767 24.99999922264319 5.331559160757991 1.1496079778654953 0.24247185100808288 2.70584421304152 82.43118426543703 34953.04018764046 1.1616310912600072 0.6706680712752633 2.619176250389118e-08 7.58183527591767 -4.181951182892496 HTDDEMT(ph)GYVATR ddPTM_PC-9_Lapatinib_30min_R1 1 HTDDEMTGYVATR 13 0 Q16539-5;Q16539-3;Q16539-4;Q16539-2;Q16539;E7EX54;B4E0K5 Q16539-5 MAPK14 Mitogen-activated protein kinase 14 1 HTDDEMT(0.596)GY(0.402)VAT(0.002)R 92.538 0.011169 18919000.0 7844.3 8124.9 8340.6 7381.8 9964.3 7105.5 12093.0 9637.4 10300.0 9459.5 True False 7732.438843531564 8106.087293242368 7654.868063647055 7924.682196962922 9378.219464567543 6801.6143287295035 12719.11636849656 10085.188787058434 9139.905536191589 11094.561971008545 0.696957560265775 0.7306360822918986 0.6899657763551339 0.7142852703577744 0.8452987588941306 0.6130583926163969 1.1464279889312599 0.9090209071265971 0.8238185121751798 1.0 13.437565088568956 -7.250012325542544 24.99973823695509 0.9622352684372155 0.7204905188679619 0.6434847073632393 0.0927846424044914 489.1229720682751 1070089.0878722125 0.03534343654106063 0.02713066184051507 5.623253658266862e-08 7.250012325542544 -0.24174474956925363 HTDDEMTGY(ph)VATR ddPTM_PC-9_AZD4547_30min_R2 6 HTDDEMTGYVATR 13 0 Q16539-5;Q16539-3;Q16539-4;Q16539-2;Q16539;E7EX54;B4E0K5 Q16539-5 MAPK14 Mitogen-activated protein kinase 14 1 HTDDEMT(0.006)GY(0.988)VAT(0.006)R;HTDDEMT(0.004)GY(0.996)VATR;HTDDEMT(0.184)GY(0.814)VAT(0.002)R;HTDDEMT(0.283)GY(0.705)VAT(0.012)R;HTDDEMT(0.308)GY(0.692)VATR;HTDDEMT(0.332)GY(0.668)VATR 174.57 0.00013273 149328500.0 86314.40000000001 85970.79999999999 112885.70000000001 197582.9 126880.6 132159.7 153428.3 234339.0 160581.1 148686.40000000002 True False 113760.58374894946 113759.17984937619 111388.76185979396 152033.21503037485 109265.41880857755 123895.73306680087 167083.121469999 198127.2921245099 169069.08911318687 143480.93439261813 0.7928620219161485 0.7928522373438691 0.7763314501074557 1.0596056937736023 0.7615326682330212 0.8634996251681444 1.1644970265721601 1.3808614570515596 1.1783383613222775 1.0 17.13049952015578 -7.283755823468711 4.276279571489373 1.2193222476274967 0.8402307388147084 0.6629371085097373 0.11806348479027635 0.11895388641762103 5.3143380714119095 0.04934542449592294 0.03398370373442126 5.2028843985149883e-08 7.283755823468711 -0.3790915088127883 HTDDEMTGY(ph)VATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 HTDDEMTGYVATR 13 0 Q16539-5;Q16539-3;Q16539-4;Q16539-2;Q16539;E7EX54;B4E0K5 Q16539-5 MAPK14 Mitogen-activated protein kinase 14 1 HTDDEMT(0.071)GY(0.929)VATR;HTDDEMTGY(0.999)VAT(0.001)R;HTDDEMT(0.009)GY(0.991)VATR;HTDDEMT(0.266)GY(0.733)VAT(0.001)R;HTDDEMT(0.122)GY(0.878)VATR;HTDDEMT(0.228)GY(0.772)VATR 158.56 2.9303e-12 75840200.0 61012.399999999994 60591.799999999996 68699.8 70780.79999999999 110673.0 92601.6 105979.9 108928.0 87111.49999999999 83451.29999999999 True False 71340.59427017077 66606.95346674413 70337.86377744243 66815.18125044975 88987.42012277791 87745.4090801999 95940.71664396905 106068.7554187559 88385.34088873315 98580.36008987263 0.7236795869393435 0.6756614949064972 0.71350788040658 0.6777737592917742 0.9026891364735417 0.890090166035153 0.9732234347338852 1.075962345055915 0.896581639670975 1.0 16.589012630379294 -6.501568057976503 1.4861192642684784 0.9863126950247603 0.690125583861488 0.8553409481754692 0.052406182725906254 0.13477294384845495 0.6078130794304258 0.020628977732697517 0.023215264780211475 3.150880569280968e-07 6.501568057976503 -0.29618711116327223 HTDDEMTGY(ph)VATR ddPTM_PC-9_Lapatinib_30min_R1 4 HTDDEMTGYVATR 13 0 Q16539-5;Q16539-3;Q16539-4;Q16539-2;Q16539;E7EX54;B4E0K5 Q16539-5 MAPK14 Mitogen-activated protein kinase 14 1 HTDDEMT(0.04)GY(0.958)VAT(0.002)R;HTDDEMT(0.343)GY(0.656)VAT(0.001)R;HTDDEMT(0.02)GY(0.98)VATR;HTDDEMT(0.076)GY(0.921)VAT(0.003)R 89.9 0.0061604 81883600.0 55736.6 42450.1 51557.6 35733.2 62321.7 53708.9 65689.7 54599.5 69837.6 59043.5 True False 54941.785863159355 42351.80940157635 47318.733146091356 38361.13873046079 58656.06013517649 51411.89554856094 69090.79124382931 57136.392095274336 61971.75406546933 69249.09030448152 0.7933936116934629 0.6115865091564316 0.6833119819774597 0.553958738833833 0.8470300458427901 0.7424197967440126 0.9977140629579944 0.8250850927290333 0.8949107315776359 1.0 16.07950749877144 -6.7602068814710785 1.5163566350507711 0.9114654764483672 0.6637537244705969 0.5986589944381935 0.09041639454837207 0.2663224353993921 1.2737859974117702 0.03853829090161154 0.03498572968583354 1.7369732032789029e-07 6.7602068814710785 -0.2477117519777703 HTENTFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HTENTFSR 8 0 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;E9PGZ1;Q05682-4;C9J813 E7EX44;Q05682-5 CALD1 Caldesmon 0 ; 68.557 0.031655 0.0 5786.0 8404.900000000001 7198.1 6883.200000000001 8332.099999999999 5390.3 7827.6 6237.5 7329.8 4960.9 False True 6765.455521290898 9239.282925951004 7369.7300029462685 6497.556619635489 6699.48481748031 5107.6231789191725 7086.113061083593 6073.7722341775425 7436.984458380763 5860.271899537204 1.1544610279644496 1.5765962884214717 1.2575747557938854 1.1087466129598207 1.1432037510084438 0.8715676109367093 1.2091782058172411 1.036431813796421 1.2690510928286576 1.0 12.516751887707862 -5.634131164012098 3.5645338648554032 1.0898772354514472 1.3760360702214662 0.3862391016018706 0.1410855455072341 0.20928325076495077 5.1020126654898155 0.03731849967764577 0.06926101061306066 2.322035397908546e-06 5.634131164012098 0.286158834770019 HTENTFSR ddPTM_PC-9_Lapatinib_30min_R1 2 HTENTFSR 8 0 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;E9PGZ1;Q05682-4;C9J813 E7EX44;Q05682-5 CALD1 Caldesmon 0 ; 134.05 0.0032413000000000003 1190530.0 3944.7799999999997 5924.4 4658.8 3760.3700000000003 6845.3 7123.200000000001 6462.799999999999 6593.3 7011.8 4607.5 False True 3888.526713815948 5910.682415794052 4275.771447488061 4036.920154026587 6442.672912377608 6818.557340990216 6797.412161276736 6899.648788025022 6222.057246472633 5403.900235892162 0.71957781307448 1.0937808171468255 0.7912380430506133 0.747038246045656 1.1922264718334403 1.2617844599909607 1.2578715121587567 1.2767905562353372 1.1514012055859868 1.0 12.399785325256069 -6.275206421595052 22.881009130759704 1.2108335475800351 0.8528517070447075 0.6647610421934371 0.12177422243113466 147.73921719461282 245543.78134493012 0.0368658354443241 0.042078586443121985 5.306321730666951e-07 6.275206421595052 -0.35798184053532767 HTENTFSRPGGR ddPTM_PC-9_AZD4547_30min_R2 1 HTENTFSRPGGR 12 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;E9PGZ1;Q05682-4;C9J813 E7EX44;Q05682-5 CALD1 Caldesmon 0 52.391000000000005 0.043324 915900.0 520.16 0.0 658.68 3046.5 2209.3 1000.5 770.31 1093.3 1234.6 1299.4 False True 685.5600599998775 0.0 649.9454728261335 2344.176492955801 1902.5768302939189 937.9385768379809 838.8660977117968 924.355606534664 1299.8584355141452 1253.9084015065785 0.5467385489850558 0.0 0.5183356870766797 1.8694958021967627 1.5173172362574183 0.7480120363744609 0.6690010982491976 0.737179530358075 1.0366454471094997 1.0 10.292216247220818 -5.536698222684923 24.999179989978195 1.0689345079429158 0.2698187244372385 0.45633344831174305 0.37016564807287405 209.4220329105979 378839.25177323085 0.11117387786941706 0.19267355837301492 2.9060412679783803e-06 5.536698222684923 -0.7991157835056772 HTGMASIDSSAPETTS(ph)DSSPTLSR ddPTM_PC-9_AZD4547_30min_R2 1 HTGMASIDSSAPETTSDSSPTLSR 24 0 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2;H0YCW2;S4R3B3;H7C453;S4R3U7 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 HTGMASIDSSAPET(0.008)T(0.035)S(0.354)DS(0.229)S(0.158)PT(0.158)LS(0.058)R 119.22 8.4978e-09 11920000.0 12251.0 12218.0 29399.0 43495.0 34456.0 40775.0 21529.0 42136.0 25376.0 29766.0 True False 16146.563163369909 16167.229563987747 29009.15005103466 33467.899741051246 29672.379153852904 38225.33280416659 23445.039292800666 35624.849388955095 26717.323553869253 28723.90140006527 0.5621298770832439 0.5628493615408041 1.0099307070789743 1.1651585651583942 1.0330205058350979 1.330784849584525 0.8162205741573597 1.2402510680138368 0.9301425729656815 1.0 14.8099640948756 -5.294468922916555 4.109533931609196 1.081948964499925 0.5527993494258623 0.6733384388517181 0.14056656147551033 0.10422591185348613 4.016977716572799 0.03454225154556792 0.08384834188763754 5.076110611733523e-06 5.294468922916555 -0.5291496150740627 HTGMASIDSSAPETTSDS(ph)SPTLSR ddPTM_PC-9_AZD4547_30min_R2 1 HTGMASIDSSAPETTSDSSPTLSR 24 0 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2;H0YCW2;S4R3B3;H7C453;S4R3U7 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 HTGMASIDSSAPET(0.004)T(0.009)S(0.062)DS(0.273)S(0.273)PT(0.273)LS(0.107)R 68.45 0.00066491 8523800.0 3611.2 3699.7 7394.4 20040.0 10836.0 8540.9 7521.9 11314.0 11055.0 8880.2 True False 4759.4864823738035 4895.555673423264 7296.34542458487 15420.087614913602 9331.608442975099 8006.836172829101 8191.3345281488855 9565.681269855657 11639.344730770192 8569.306900922515 0.5554109028189232 0.5712895721935506 0.8514510577044911 1.799455637801183 1.0889571993238474 0.9343621678396345 0.9558923052769951 1.1162724570905354 1.3582597595515196 1.0 13.064962806264877 -5.527193784197472 24.98683607742164 1.1733072987907285 0.6003551331744826 0.5190767216435619 0.2395623787530756 95.18388616464037 551173.819100985 0.06830079520621513 0.11891385852910165 2.9703403564552574e-06 5.527193784197472 -0.5729521656162458 HTGMASIDSSAPETTSDS(ph)SPTLSR ddPTM_PC-9_Lapatinib_30min_R1 2 HTGMASIDSSAPETTSDSSPTLSR 24 0 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2;H0YCW2;S4R3B3;H7C453;S4R3U7 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 HTGMASIDSSAPETT(0.005)S(0.236)DS(0.444)S(0.269)PT(0.011)LS(0.034)R;HTGMASIDSSAPETT(0.003)S(0.017)DS(0.334)S(0.334)PT(0.088)LS(0.223)R 138.37 1.4325e-06 6258800.0 19476.8 14228.7 23553.7 19113.6 25461.2 26169.0 26119.8 25336.0 27595.0 21289.3 True False 19199.05726039232 14195.754319358724 21617.20570591128 20519.277905100458 23963.622274645204 25049.81287291849 27472.155438837053 26513.203053615343 24486.960511767644 24969.127138790893 0.768911830744998 0.5685322614784099 0.8657573645146682 0.821785951549049 0.9597300755226008 1.0032314198922174 1.1002449259092268 1.0618394029651779 0.9806894880889058 1.0 14.60785776851489 -5.963535251929068 1.0234536251262525 1.0421805019418082 0.6682765334951313 0.7899415968483581 0.06945667399423355 0.23363358454841593 0.4935390944010061 0.02761701486135859 0.06130792286285753 1.08758885384478e-06 5.963535251929068 -0.37390396844667695 HTGMASIDSSAPETTSDSSPT(ph)LSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HTGMASIDSSAPETTSDSSPTLSR 24 0 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2;H0YCW2;S4R3B3;H7C453;S4R3U7 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 HTGMASIDSSAPET(0.001)T(0.001)S(0.01)DS(0.13)S(0.13)PT(0.529)LS(0.199)R;HTGMASIDSSAPET(0.023)T(0.017)S(0.184)DS(0.095)S(0.095)PT(0.446)LS(0.139)R 108.09 1.0368e-06 16646300.0 13783.3 20431.0 28202.0 36556.0 38318.0 36971.0 33065.0 21567.4 28908.0 25955.0 True False 16116.540457415964 22459.254656224934 28874.442636680604 34507.88583615106 30809.862968064554 35032.17567627416 29932.843830130438 21001.278602549228 29330.724811437023 30660.43604033305 0.5256461596376206 0.7325158268029958 0.9417492497072444 1.1254858147078137 1.0048736073921107 1.1425856967653751 0.9762693456399157 0.684963468064269 0.9566310398473516 1.0 14.904090594117989 -5.032743647560137 2.2543884135097825 0.9815759425788521 0.5123833798462532 0.6129354990120472 0.11723212236532096 0.28486753295778244 2.4177204930677174 0.035291271795151485 0.21606886674041528 9.273770677798248e-06 5.032743647560137 -0.4691925627325989 HTGPGILS(ph)MANAGPNTNGSQFFICTAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HTGPGILSMANAGPNTNGSQFFICTAK 27 0 P62937;F8WE65;C9J5S7;P62937-2 P62937 PPIA Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase 1 HT(0.197)GPGILS(0.765)MANAGPNT(0.036)NGS(0.001)QFFICTAK 65.581 0.00026778 3845200.0 7587.0 11855.0 9449.0 13833.0 13351.0 11461.0 10832.0 10130.0 10393.0 11986.0 True False 8871.329249919465 13031.886053034445 9674.299995532054 13057.981857191095 10734.967390955424 10859.964984062593 9805.914543111232 9864.098233622206 10544.977963375717 14158.9669188762 0.6265520147584033 0.9203980860821721 0.6832631258312104 0.9222411445698546 0.7581744806991512 0.7670026384188029 0.6925586166910495 0.6966679341888823 0.7447561692737308 1.0 13.789428385409227 -6.468446594139374 24.999671031194847 0.7565192308926251 0.7963399546276922 0.0 0.11834700573424509 1495.1175357766556 686678.1144355445 0.03432404497636407 0.038919623791311295 3.4005832072789404e-07 6.468446594139374 0.039820723735067176 HTGPGILSMANAGPNTNGSQFFICTAK ddPTM_PC-9_Lapatinib_30min_R1 1 HTGPGILSMANAGPNTNGSQFFICTAK 27 0 P62937;F8WE65;C9J5S7;P62937-2 P62937 PPIA Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase 0 121.44 1.8687e-12 9689700.0 64758.0 57112.0 71488.0 47026.0 67768.0 72119.0 60890.0 53459.0 60987.0 55306.0 False True 63834.539044837235 56979.760672950804 65610.53259166033 50484.44891413729 63782.01947701421 69034.63848760024 64042.586262941826 55942.90030167442 54118.00183841908 64865.56840938724 0.9841051363638279 0.8784284493328326 1.011484739909645 0.7782934791461915 0.9832954684751329 1.0642724665865975 0.9873124961882502 0.8624436919846439 0.8343101458213261 1.0 15.985165257363807 -11.932216884839564 2.1736062526901843 1.521135268288955 0.9328638027768072 0.05434330026296419 0.08550449692924647 13410744.843471784 1194051.5923618108 34452028.02584854 0.02187935945490546 1.1689154937477328e-12 11.932216884839564 -0.5882714655121477 HTGPNS(ph)PDTANDGFVR ddPTM_PC-9_AZD4547_30min_R2 11 HTGPNSPDTANDGFVR 16 0 P31943;G8JLB6;E9PCY7;P55795;D6RBM0;E5RGV0;D6RIU0;D6RIH9;D6RJ04;D6RDU3;D6RIT2;D6RFM3;D6R9T0;D6RAM1;H0YAQ2;E5RGH4;E7EQJ0 P31943;E7EQJ0 HNRNPH1;HNRNPH2 Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;Heterogeneous nuclear ribonucleoprotein H2 1 HT(0.003)GPNS(0.994)PDT(0.004)ANDGFVR;HTGPNS(1)PDTANDGFVR;HTGPNS(0.999)PDT(0.001)ANDGFVR;HTGPNS(1)PDTANDGFVR;HTGPNS(0.943)PDT(0.057)ANDGFVR;HTGPNS(1)PDTANDGFVR;HT(0.051)GPNS(0.592)PDT(0.357)ANDGFVR;HTGPNS(0.999)PDT(0.001)ANDGFVR;HT(0.03)GPNS(0.965)PDT(0.005)ANDGFVR;HTGPNS(0.999)PDT(0.001)ANDGFVR;HT(0.425)GPNS(0.57)PDT(0.005)ANDGFVR 231.21 2.5672e-29 2124745000.0 304747.0 272626.7 375800.80000000005 570065.1 488207.39999999997 393137.2 360606.39999999997 483808.0 333380.7 400035.60000000003 True False 401650.20686862274 360747.94926930923 370817.43584811897 438645.39861299767 420428.2295831413 368554.2687357004 392699.6710128378 409046.5904018312 351002.52319181134 386030.4754053593 1.0404624309696318 0.9345063984663345 0.9605910918269716 1.1362973302882085 1.089106317685571 0.9547284274607915 1.0172763448286704 1.0596225336155218 0.9092611738056015 1.0 18.558355220843758 -10.44978898819049 14.847735262456434 0.9999999999950916 1.013461311500411 0.0015686861933871254 0.06857236076962896 0.0 0.0 0.0683507068481576 0.016577481407093073 3.549858252417799e-11 10.44978898819049 0.013461311505319373 HTGPNS(ph)PDTANDGFVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 15 HTGPNSPDTANDGFVR 16 0 P31943;G8JLB6;E9PCY7;P55795;D6RBM0;E5RGV0;D6RIU0;D6RIH9;D6RJ04;D6RDU3;D6RIT2;D6RFM3;D6R9T0;D6RAM1;H0YAQ2;E5RGH4;E7EQJ0 P31943;E7EQJ0 HNRNPH1;HNRNPH2 Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;Heterogeneous nuclear ribonucleoprotein H2 1 HT(0.006)GPNS(0.994)PDTANDGFVR;HTGPNS(1)PDTANDGFVR;HT(0.105)GPNS(0.895)PDT(0.001)ANDGFVR;HT(0.007)GPNS(0.993)PDTANDGFVR;HTGPNS(0.999)PDT(0.001)ANDGFVR;HTGPNS(0.998)PDT(0.002)ANDGFVR;HT(0.007)GPNS(0.987)PDT(0.005)ANDGFVR;HTGPNS(1)PDTANDGFVR;HT(0.001)GPNS(0.999)PDTANDGFVR;HT(0.001)GPNS(0.999)PDTANDGFVR;HT(0.002)GPNS(0.897)PDT(0.101)ANDGFVR;HTGPNS(1)PDTANDGFVR;HT(0.047)GPNS(0.95)PDT(0.003)ANDGFVR;HTGPNS(1)PDTANDGFVR;HTGPNS(0.989)PDT(0.011)ANDGFVR 242.67 9.784599999999999e-110 1698725800.0 430858.9 508466.0 513311.6 570344.1 621552.5 508177.4 529008.6 513952.89999999997 482509.0 380071.0 True False 503794.801918826 558943.1441452735 525550.8952890841 538389.5691575209 499763.74947695463 481527.6825488155 478897.0757174028 500462.18095311115 489564.78130765376 448974.863659619 1.1221002392257924 1.2449319313542342 1.1705575029419009 1.199153032241221 1.1131218915093657 1.072504769251126 1.066645628697086 1.114677505270153 1.0904057686374335 1.0 18.776275150831438 -6.426910880316396 3.1169323672929337 1.076336948419906 1.1877602967039056 0.6488741027915599 0.0396988376621774 0.1629807905891187 3.0351130850248365 0.0125729301848614 0.014175804921337083 3.7418736575766437e-07 6.426910880316396 0.11142334828399969 HTGPNS(ph)PDTANDGFVR ddPTM_PC-9_Lapatinib_30min_R1 11 HTGPNSPDTANDGFVR 16 0 P31943;G8JLB6;E9PCY7;P55795;D6RBM0;E5RGV0;D6RIU0;D6RIH9;D6RJ04;D6RDU3;D6RIT2;D6RFM3;D6R9T0;D6RAM1;H0YAQ2;E5RGH4;E7EQJ0 P31943;E7EQJ0 HNRNPH1;HNRNPH2 Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;Heterogeneous nuclear ribonucleoprotein H2 1 HT(0.049)GPNS(0.896)PDT(0.056)ANDGFVR;HTGPNS(0.783)PDT(0.217)ANDGFVR;HT(0.001)GPNS(0.999)PDTANDGFVR;HT(0.001)GPNS(0.905)PDT(0.094)ANDGFVR;HT(0.003)GPNS(0.96)PDT(0.037)ANDGFVR;HTGPNS(0.989)PDT(0.011)ANDGFVR;HT(0.001)GPNS(0.939)PDT(0.06)ANDGFVR;HTGPNS(1)PDTANDGFVR;HTGPNS(1)PDTANDGFVR;HT(0.022)GPNS(0.977)PDT(0.002)ANDGFVR;HTGPNS(1)PDTANDGFVR 205.12 6.4351e-17 1494526600.0 321214.0 255205.0 314331.0 230516.6 284787.0 276163.0 254075.6 260543.0 305769.7 215590.5 True False 316633.4294565672 254614.08850224884 288487.91853274935 247469.55974483528 268036.3885727843 264352.15225739585 267230.3913665415 272648.7789389843 271330.6964883147 252855.0306687158 1.252233062633475 1.0069567840073457 1.1409222026146628 0.9787013495059292 1.0600397700766284 1.0454692222585964 1.0568521838770926 1.0782810142947157 1.073068215296081 1.0 17.947950956277964 -4.753364432530642 24.99120804668893 1.0525355600568658 1.2522334296386977 0.6575863058812839 0.04394361102346294 173.82177646301975 537919.8292031506 0.010161712565227857 0.10956966623092927 1.764556494766582e-05 4.753364432530642 0.1996978695818319 HTGPNS(ph)PDTANDGFVRL ddPTM_PC-9_Lapatinib_30min_R1 1 HTGPNSPDTANDGFVRL 17 1 E7EQJ0 E7EQJ0 HNRNPH1 1 HT(0.197)GPNS(0.803)PDTANDGFVRL 65.765 0.0096469 1666900.0 12161.0 8504.8 10766.0 9006.9 7786.0 8705.4 4502.3 5652.4 8237.3 7073.4 True False 11987.581909945726 8485.107658133353 9880.861037961804 9669.297472137605 7328.042787864962 8333.090335278564 4735.407064076911 5915.0311391007035 7309.52853138553 8296.027765286948 1.4449785185273054 1.0227916176507474 1.1910351938919816 1.1655334029373463 0.8833194626623209 1.0044675079496115 0.5708041484493658 0.7129955813131383 0.8810877612983379 1.0 13.018205007257627 -6.393427477006296 1.2621797371406691 0.7815388559860444 1.2203405518222878 0.5763602765128494 0.153372650990006 0.3138792774782757 1.029315928910851 0.06340374588140288 0.08043132724479653 4.041778626868889e-07 6.393427477006296 0.4388016958362434 HTGPNSPDT(ph)ANDGFVR ddPTM_PC-9_Lapatinib_30min_R1 1 HTGPNSPDTANDGFVR 16 0 P31943;G8JLB6;E9PCY7;P55795;D6RBM0;E5RGV0;D6RIU0;D6RIH9;D6RJ04;D6RDU3;D6RIT2;D6RFM3;D6R9T0;D6RAM1;H0YAQ2;E5RGH4;E7EQJ0 P31943;E7EQJ0 HNRNPH1;HNRNPH2 Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;Heterogeneous nuclear ribonucleoprotein H2 1 HTGPNS(0.117)PDT(0.883)ANDGFVR 88.10799999999999 0.009973000000000001 335380000.0 11505.0 10236.0 19223.0 17396.0 18530.0 15698.0 12958.0 11835.0 15596.0 12253.0 True False 11340.936590241392 10212.29917089797 17642.559142925864 18675.359871354834 17440.10183138168 15026.633133825308 13628.901836019058 12384.89730579167 13839.414246839215 14370.91472390377 0.7891589928772952 0.7106227659893776 1.2276573538899527 1.2995247853145557 1.213569363289923 1.0456281609430784 0.9483670384147163 0.8618029919272522 0.9630155430412173 1.0 13.810864273330763 -7.271004709348531 4.72100506916093 0.9301369538336824 1.0601568531399046 0.0731498417733436 0.17757353471433768 0.5545238856247882 35.14686640319879 0.08504606860372001 0.05966442909007378 5.3579084753963415e-08 7.271004709348531 0.13001989930622215 HTGPNSPDTANDGFVR ddPTM_PC-9_Lapatinib_30min_R1 3 HTGPNSPDTANDGFVR 16 0 P31943;G8JLB6;E9PCY7;P55795;D6RBM0;E5RGV0;D6RIU0;D6RIH9;D6RJ04;D6RDU3;D6RIT2;D6RFM3;D6R9T0;D6RAM1;H0YAQ2;E5RGH4;E7EQJ0 P31943;E7EQJ0 HNRNPH1;HNRNPH2 Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;Heterogeneous nuclear ribonucleoprotein H2 0 ;; 174.24 1.1034000000000001e-05 26024300.0 48527.0 49928.5 60785.0 53537.0 58465.0 59813.0 49792.0 44872.4 56646.2 44887.4 False True 47834.996081238074 49812.893625847886 55787.49193688538 57474.28957419654 55026.2036466125 57254.937420913055 52369.98612587291 46957.33551874994 50266.10844506948 52646.12728129912 0.9086137680298081 0.9461834364318445 1.0596694347297626 1.0917097333123773 1.045208954356626 1.087543194107861 0.9947547679252695 0.8919428254968729 0.9547921383939086 1.0 15.684039788149756 -10.452203737146139 5.9327169113925775 0.9999999998577127 1.0017137383738912 0.0 0.06838684608177212 8.485744238203457e-10 3.4001180565221433e-18 0.07440249812705177 0.01804524858954604 3.530175226135693e-11 10.452203737146139 0.001713738516178509 HTLGDS(ph)DNES ddPTM_PC-9_Lapatinib_30min_R1 2 HTLGDSDNES 10 0 G3V1D1;G3V192;P02794 G3V1D1 FTH1 Ferritin;Ferritin heavy chain;Ferritin heavy chain, N-terminally processed 1 HT(0.001)LGDS(0.974)DNES(0.024);HT(0.001)LGDS(0.999)DNES 68.536 0.040734 9847000.0 51504.0 58127.0 60230.0 50710.0 57552.0 63528.0 50466.0 69267.0 64535.0 49760.0 True False 50769.54351532316 57992.41050281226 55278.121894523436 54439.38256360098 54166.904511585446 60811.05553100106 53078.88254796557 72485.39769161578 57266.3887163227 58360.94969896776 0.8699231896875923 0.9936851747948505 0.9471765312191476 0.9328049465336898 0.928136104552519 1.041981939030657 0.9094931254846319 1.2420188167859416 0.9812449765075633 1.0 15.832715739755958 -7.713617545242559 24.99999732735651 1.0837266193498791 0.9505148491009557 0.3558967874617378 0.07861459089570288 109.36169675354917 57171.24429518425 0.03424448600815989 0.0197710001104078 1.9336704245652887e-08 7.713617545242559 -0.1332117702489234 HTNPSSS(ph)SPGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HTNPSSSSPGTR 12 0 Q8WUH2 Q8WUH2 TGFBRAP1 Transforming growth factor-beta receptor-associated protein 1 1 HTNPS(0.106)S(0.106)S(0.393)S(0.393)PGT(0.001)R;HTNPS(0.059)S(0.059)S(0.441)S(0.441)PGTR 96.866 0.012568000000000001 521700.0 3130.23 5956.2 8235.7 7280.0 8499.9 4963.2 5507.1 4786.700000000001 4619.0 3128.29 True False 3660.1161141393686 6547.492172845529 8432.070322066182 6872.125202078446 6834.405612042695 4702.92105478575 4985.427620048732 4661.05419692788 4686.5441367105195 3695.4242134699866 0.9904454543535439 1.7717836423162534 2.281759775056652 1.8596309395357757 1.8494238326227828 1.2726336093278257 1.3490812778345245 1.26130423130804 1.268201934605466 1.0 11.85152427164256 -6.76703556144161 23.66617988773385 1.254002806150868 1.7873503381021643 0.40934435079119613 0.31031877718950646 74.4731670419543 314942.3764864802 0.11245303224112384 0.1020780734728151 1.7098752992192697e-07 6.76703556144161 0.5333475319512964 HTNPSSS(ph)SPGTR ddPTM_PC-9_Lapatinib_30min_R1 1 HTNPSSSSPGTR 12 0 Q8WUH2 Q8WUH2 TGFBRAP1 Transforming growth factor-beta receptor-associated protein 1 1 HTNPS(0.002)S(0.006)S(0.685)S(0.307)PGTR 136.14 3.5416999999999996e-05 2680300.0 851.86 964.44 3869.1 1025.3 4164.3 3186.8 3995.5 2791.3 3274.8 2664.2 True False 839.7123201880087 962.2068984350176 3550.9975331579044 1100.7039823005348 3919.3640613288067 3050.507992793634 4202.367439868355 2920.9939881416367 2905.957538827203 3124.7034201766464 0.26873344675397637 0.3079354322787607 1.1364270638386407 0.35225870564007306 1.2543155411233353 0.9762552097252103 1.3448852178203798 0.9348067945522031 0.9299946740746751 1.0 11.609503548182257 -5.134256742497874 0.8204992187252167 1.0601038145937294 2.843796032712922e-11 0.5196649522792471 0.2613407133067633 1.2804563588374642 0.9396058391429165 0.10069830243276057 1.1218274381239182 7.340797728548662e-06 5.134256742497874 -1.0601038145652915 HTNPSSS(ph)SPGTRT ddPTM_PC-9_AZD4547_30min_R2 1 HTNPSSSSPGTRT 13 1 Q8WUH2 Q8WUH2 TGFBRAP1 Transforming growth factor-beta receptor-associated protein 1 1 HTNPS(0.046)S(0.046)S(0.454)S(0.454)PGTRT 177.93 0.00019283 5415100.0 2358.2 924.92 5997.7 11965.0 6941.9 5457.0 4627.0 7545.7 4870.4 6750.7 True False 3108.0585463928596 1223.8823022035963 5918.166579172434 9206.654107407245 5978.137010916282 5115.772927341195 5038.794036313286 6379.685447936166 5127.839400881337 6514.360047753165 0.47710880633084507 0.18787452539190236 0.9084801171242658 1.4132860388308848 0.917685999406522 0.785307058535343 0.7734902583487369 0.9793265034738986 0.7871593469338486 1.0 12.669407744149211 -5.2747396368557675 20.199128107900126 0.9486898730742602 0.33249213684247425 0.6338954229608714 0.1863620695962554 34.312802170670416 52112.50526627191 0.051620237484514754 0.10919980101606858 5.312028092805273e-06 5.2747396368557675 -0.616197736231786 HTNPSSS(ph)SPGTRT ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HTNPSSSSPGTRT 13 1 Q8WUH2 Q8WUH2 TGFBRAP1 Transforming growth factor-beta receptor-associated protein 1 1 HTNPS(0.064)S(0.064)S(0.654)S(0.218)PGTRT;HTNPS(0.207)S(0.207)S(0.379)S(0.206)PGTRT 171.99 0.00031527 3949160.0 3634.0 3195.4 8022.77 8760.49 11173.46 10978.93 8578.68 7389.09 8662.98 6526.67 True False 4249.16442522833 3512.6181943370934 8214.06326332466 8269.668147191791 8984.100722353734 10403.175583498329 7766.045326135287 7195.134216888006 8789.659693751997 7709.903605908709 0.5511306810595997 0.45559819861367606 1.065391175193108 1.072603312556864 1.1652675807085975 1.349326284121834 1.0072817668152882 0.9332327075235812 1.1400479361396665 1.0 12.912497107429267 -5.275579740449159 8.626280972842986 1.0977636370025672 0.502849686721859 0.8209966122610439 0.10984852871052762 0.07437699488997333 40.147429095060595 0.030741240139935913 0.06781822512119048 5.301762384730726e-06 5.275579740449159 -0.5949139502807081 HTNPSSSS(ph)PGTR ddPTM_PC-9_AZD4547_30min_R2 2 HTNPSSSSPGTR 12 0 Q8WUH2 Q8WUH2 TGFBRAP1 Transforming growth factor-beta receptor-associated protein 1 1 HTNPSSS(0.027)S(0.973)PGTR;HTNPS(0.021)S(0.021)S(0.216)S(0.742)PGTR 182.72 0.00028863 5540900.0 4895.3 7639.0 15302.1 18215.4 14308.9 18467.2 10381.6 20206.4 15534.4 13085.3 True False 6451.90357143456 10108.157361213161 15099.184155785484 14016.120955124603 12322.356224592691 17312.44306465004 11305.542288175919 17083.9651768792 16355.516669893852 12627.187629855347 0.510953330271253 0.8005074176068894 1.1957677828501907 1.109995461062549 0.9758591212708425 1.3710450475699762 0.8953333568470488 1.352950924439135 1.2952620289907908 1.0 13.624245732509799 -5.003731895364632 2.388446535408493 1.155019437017478 0.4838540564704842 0.6428964063524962 0.15405331853484996 0.21937643246659064 2.1112720996759973 0.04006628165414083 0.25156595043917207 9.914438077221612e-06 5.003731895364632 -0.6711653805469938 HTNPSSSS(ph)PGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HTNPSSSSPGTR 12 0 Q8WUH2 Q8WUH2 TGFBRAP1 Transforming growth factor-beta receptor-associated protein 1 1 HTNPS(0.036)S(0.036)S(0.115)S(0.814)PGTR;HTNPS(0.033)S(0.015)S(0.109)S(0.842)PGT(0.001)R 129.17 0.00018325 3153600.0 4359.1 8235.3 12688.8 9170.2 12849.0 7159.099999999999 9890.900000000001 7821.7 7288.900000000001 7420.0 True False 5097.009533850529 9052.846158798357 12991.349114541967 8656.42342418953 10331.330687318268 6783.66419312473 8953.9623480852 7616.3886627761885 7395.486373255964 8765.18726331232 0.5815060626467887 1.032818339967483 1.4821530589447556 0.9875913844330476 1.1786776912983044 0.773932602845637 1.021536914055792 0.8689362171023365 0.8437339843508657 1.0 13.097569198346964 -6.757345062512018 24.998245569482574 0.9009307711164806 1.0717112335132493 0.10423013986209073 0.2176185954611323 238.4529938501576 1455897.4103365242 0.07517099724550269 0.07258360062292085 1.7484569249740633e-07 6.757345062512018 0.1707804623967687 HTNPSSSS(ph)PGTR ddPTM_PC-9_Lapatinib_30min_R1 1 HTNPSSSSPGTR 12 0 Q8WUH2 Q8WUH2 TGFBRAP1 Transforming growth factor-beta receptor-associated protein 1 1 HTNPSS(0.003)S(0.233)S(0.76)PGT(0.004)R 121.92 0.00024058 2945300.0 2709.4 3947.0 5870.5 3560.9 4792.7 6248.9 4927.9 6075.3 8232.7 4487.3 True False 2670.763459156891 3937.8609640029586 5387.8501507853225 3822.780464814176 4510.8028088107385 5981.6491138973715 5183.0425496001135 6357.580616973058 7305.44663182568 5262.9238260485945 0.5074676258732973 0.7482268590916518 1.0237370573593354 0.7263605917861671 0.8570906511100791 1.1365638781035514 0.9848218824575966 1.2079940404051661 1.3880965929371265 1.0 12.36164879851667 -5.503070610569475 0.40711483893351286 1.2099414610844565 0.3844152974077017 0.6201166527255619 0.15059479918820545 2.2160107906096203 0.44513756251654185 0.13837654828541138 0.8441004170797527 3.139998129983597e-06 5.503070610569475 -0.8255261636767548 HTNPSSSS(ph)PGTRT ddPTM_PC-9_AZD4547_30min_R2 3 HTNPSSSSPGTRT 13 1 Q8WUH2 Q8WUH2 TGFBRAP1 Transforming growth factor-beta receptor-associated protein 1 1 HTNPS(0.02)S(0.02)S(0.17)S(0.703)PGT(0.075)RT(0.012);HTNPSSS(0.012)S(0.554)PGT(0.185)RT(0.249);HTNPSSS(0.033)S(0.955)PGT(0.007)RT(0.005) 127.88 5.1219e-05 22695400.0 25510.9 30428.6 63200.3 110030.0 88339.4 67072.0 46303.0 77351.5 44650.5 71158.1 True False 33622.835540316184 40264.04988629541 62362.22272765755 84664.28344655407 76074.99915903971 62877.97723705853 50423.87729920338 65398.60303564068 47010.63427419758 68666.87657783995 0.48965144791756676 0.5863678660358544 0.9081849333421257 1.232971232506544 1.1078849505088817 0.9156958983823998 0.7343260653780207 0.95240392886526 0.6846187946368419 1.0 16.06732672137676 -5.235207415157981 3.874887334146073 0.9504489871065274 0.5175419472230016 0.5385958240877349 0.15077398681007181 0.17761774939798758 5.986441312203263 0.043354559818499526 0.12071892630349149 5.81825276859735e-06 5.235207415157981 -0.43290703988352575 HTNPSSSS(ph)PGTRT ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HTNPSSSSPGTRT 13 1 Q8WUH2 Q8WUH2 TGFBRAP1 Transforming growth factor-beta receptor-associated protein 1 1 HTNPSS(0.005)S(0.043)S(0.614)PGT(0.169)RT(0.169);HTNPS(0.033)S(0.033)S(0.096)S(0.832)PGT(0.005)RT(0.001);HTNPS(0.001)S(0.001)S(0.032)S(0.953)PGT(0.012)RT(0.002);HTNPS(0.05)S(0.05)S(0.217)S(0.68)PGT(0.002)RT(0.001) 153.0 0.00021003 5811900.0 10883.5 9858.7 19248.0 19745.940000000002 23975.3 24895.440000000002 19691.1 17809.9 20182.58 15225.26 True False 12725.861591076642 10837.406582121523 19706.945318446487 18639.638999001218 19277.512073131118 23589.87930048262 17825.816456781533 17342.40899614887 20477.71205080991 17985.47911490815 0.7075631129853074 0.6025642415685443 1.0957142254893513 1.036371557294286 1.071837561288651 1.3116069441224385 0.9911226908604135 0.9642450381971621 1.1385691712730606 1.0 14.134544971466182 -5.264358986554903 24.97779153763291 1.0786994871803062 0.6550636541649945 0.754249969995075 0.09614261626314484 108.61175344539387 929203.2497838619 0.025663229038942522 0.05743784153922312 5.4405275450208185e-06 5.264358986554903 -0.4236358330153117 HTNPSSSS(ph)PGTRT ddPTM_PC-9_Lapatinib_30min_R1 2 HTNPSSSSPGTRT 13 1 Q8WUH2 Q8WUH2 TGFBRAP1 Transforming growth factor-beta receptor-associated protein 1 1 HTNPS(0.029)S(0.029)S(0.253)S(0.69)PGTRT;HTNPS(0.017)S(0.017)S(0.136)S(0.773)PGT(0.049)RT(0.008) 162.67 0.00012257 6798700.0 9449.3 5510.4 11237.7 8014.4 10185.4 10925.9 5744.5 7801.1 13019.1 5239.7 True False 9314.5512492106 5497.641007357967 10313.779684776455 8603.805711254661 9586.314797266863 10458.624726516879 6041.922101945631 8163.567585315703 11552.751860799204 6145.3751635386125 1.5157009948676792 0.8945981101326825 1.6782994382457854 1.4000456412006004 1.5599234452184199 1.701869202155369 0.9831657044785836 1.3284083344091526 1.8799099409493059 1.0 12.58528537175397 -10.581962332197024 4.825916318024533 0.999988205048245 1.4227080091435318 0.16529071049934418 0.29347416286555567 204993173.2404898 0.21123968817993283 27719.80162690542 0.07001141228552166 2.6184101017760375e-11 10.581962332197024 0.42271980409528676 HTNPSSSSPGT(ph)RT ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HTNPSSSSPGTRT 13 1 Q8WUH2 Q8WUH2 TGFBRAP1 Transforming growth factor-beta receptor-associated protein 1 1 HTNPSSS(0.001)S(0.076)PGT(0.461)RT(0.461) 109.14 0.00069594 1127000.0 2889.9 3554.1 4954.8 3815.0 6178.4 5552.0 5137.5 5608.7 5833.9 4237.3 True False 3379.102991873237 3906.927559771379 5072.94122318364 3601.257918396878 4967.786872015504 5260.843346262588 4650.838807721006 5461.477567908869 5919.20975084553 5005.488947551656 0.6750795031774197 0.7805286557834439 1.013475661686353 0.7194617660994672 0.9924678536040734 1.0510148761462823 0.9291477528875335 1.0910977179522596 1.1825437660272538 1.0 12.28929528634159 -4.618514953085544 0.3524915729994996 1.094366107930932 0.3524641565073045 0.5944318405327564 0.10068988604761236 5.264875373113063 0.4800947862433912 0.09639212272758496 1.7100054601798027 2.407049641094475e-05 4.618514953085544 -0.7419019514236274 HTNYTMEHIR ddPTM_PC-9_AZD4547_30min_R2 6 HTNYTMEHIR 10 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144;P12814-4;P12814-3;P12814;P12814-2;H9KV75;P35609-2;P35609;A0A494C1A0;H7C5W8;H0YJ11;H0YJW3;A0A494C060;F6THM6 O43707;P12814-4 ACTN4;ACTN1;ACTN2 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2 0 ;;;;; 90.149 0.004959000000000001 117098300.0 14189.5 11275.800000000001 19228.9 29574.300000000003 22546.9 18498.88 18939.6 19778.0 17234.6 23710.0 False True 18701.465840065084 14920.481839712957 18973.912222059942 22756.40205338019 19416.65212282349 17342.142109241962 20625.187709133133 16721.764553226534 18145.585770866757 22879.920116762336 0.8173746125260278 0.652121238342169 0.8292822756911303 0.9946014643953387 0.8486328633900438 0.7579634028764255 0.9014536590983403 0.7308489045368562 0.7930790701307082 1.0 14.481794394631136 -11.92151728762008 2.1485990505665757 2.333757624693832 0.814440477591202 0.28437527522066375 0.08854848586191275 3862721.9545325646 350347.08652505727 25114863.082225762 0.02393341164659306 1.198071431550293e-12 11.92151728762008 -1.51931714710263 HTNYTMEHIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 HTNYTMEHIR 10 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144;P12814-4;P12814-3;P12814;P12814-2;H9KV75;P35609-2;P35609;A0A494C1A0;H7C5W8;H0YJ11;H0YJW3;A0A494C060;F6THM6 O43707;P12814-4 ACTN4;ACTN1;ACTN2 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2 0 ;;;; 102.53 0.001773 93954000.0 12750.54 10516.130000000001 13856.599999999999 14872.499999999998 17661.4 13889.8 18290.9 17762.4 12050.529999999999 13408.23 False True 14908.954587355749 11560.10188771802 14186.993895448126 14039.242042295566 14200.775453420732 13161.394436404558 16558.253537351673 17296.155820818465 12226.746203887025 15839.03595950972 0.9412791678400382 0.7298488315368311 0.8956980672128778 0.8863697309725747 0.8965681680200126 0.8309466857736685 1.045407913693771 1.0919954891846744 0.7719375241740085 1.0 13.951196908227098 -7.252813659988249 24.901827768451863 0.985001523402899 0.8613916682873903 0.2588686229182663 0.09400452946241147 776.7549379604126 2242439.967924884 0.03541792447798912 0.026982994131439793 5.587098654568441e-08 7.252813659988249 -0.1236098551155087 HTNYTMEHIR ddPTM_PC-9_Lapatinib_30min_R1 7 HTNYTMEHIR 10 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144;P12814-4;P12814-3;P12814;P12814-2;H9KV75;P35609-2;P35609;A0A494C1A0;H7C5W8;H0YJ11;H0YJW3;A0A494C060;F6THM6 O43707;P12814-4 ACTN4;ACTN1;ACTN2 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2 0 ;;;;;; 131.09 8.0528e-05 69305000.0 23401.55 25244.149999999998 30079.4 29373.969999999998 33598.600000000006 23431.91 30175.949999999997 26378.300000000003 31309.4 22174.02 False True 23067.839605681325 25185.69872167096 27606.38784184175 31534.229742491403 31622.396405389132 22429.781831750064 31738.313038942684 27603.932116718577 27783.00566940163 26006.769811975566 0.8869936471333351 0.9684285631687131 1.0615077551511067 1.2125392722924997 1.215929415072059 0.8624593516962504 1.2203865865851538 1.0614133287713245 1.0682989802373744 1.0 14.666599599067103 -5.138567398059961 2.563101174418298 1.0970171687396009 0.8958900352546606 0.2855768419955276 0.10493907920599486 0.384164851701995 4.610975174064804 0.028049634036276482 0.11622319411201555 7.268295939450557e-06 5.138567398059961 -0.20112713348494027 HTPDQS(ph)PGMESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HTPDQSPGMESR 12 0 Q7Z2K8;Q7Z2K8-2 Q7Z2K8 GPRIN1 G protein-regulated inducer of neurite outgrowth 1 1 HTPDQS(0.997)PGMES(0.003)R 76.85 0.012623 2586600.0 13557.0 13799.0 17153.0 13315.0 17301.0 12725.0 14102.0 10836.0 12645.0 11921.0 True False 15851.93233704471 15168.873525586012 17561.992573114756 12569.003717812444 13910.993246267672 12057.678598917773 12766.156470361391 10551.566481691032 12829.909203010282 14082.182933415923 1.1256729451674221 1.077167765630388 1.2471072600144624 0.8925465446118568 0.987843526251741 0.8562364695821301 0.9065467002326959 0.7492848609893419 0.9110738912903842 1.0 13.781583368574944 -5.776932203496636 24.99028418100233 0.8921044231848844 1.1427011479181088 0.6895713082051695 0.07651485301741486 125.00032914587916 201628.1082381205 0.02158626504545913 0.03214828194003623 1.6713515039803893e-06 5.776932203496636 0.2505967247332245 HTPPTIGGS(ph)LPYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HTPPTIGGSLPYR 13 0 H0Y6B5;B7Z836;E7EW77;E7EP65;A0A0C4DG21;F8WAL6;Q9NYB9-3;Q9NYB9-2;Q9NYB9-4;Q9NYB9;H7C3Q7;E9PEZ7 H0Y6B5 ABI2 Abl interactor 2 1 HT(0.084)PPT(0.111)IGGS(0.805)LPYR 85.988 0.0044309 6227200.0 16597.0 20997.0 33197.0 37655.0 34627.0 29508.0 27753.0 22781.0 26676.0 23589.0 True False 19406.544294307816 23081.44339566127 33988.54238032359 35545.31242915715 27842.087921999344 27960.5485341348 25124.034925680033 22183.022888464693 27066.086033966178 27865.49896957873 0.6964362746740796 0.8283161705038801 1.219735645768608 1.2756029406816871 0.999159855432521 1.0034110124731603 0.9016179811855656 0.796074849141668 0.9713117308078608 1.0 14.766192366609527 -7.225763873517115 4.426251126051034 0.8996056679163915 1.0190178050816994 0.053858925183173034 0.16520404257738694 0.5865996722358694 27.243559737303432 0.07430628333026731 0.054708314010358625 5.946153639020195e-08 7.225763873517115 0.11941213716530785 HTPPTIGGS(ph)LPYR ddPTM_PC-9_Lapatinib_30min_R1 3 HTPPTIGGSLPYR 13 0 H0Y6B5;B7Z836;E7EW77;E7EP65;A0A0C4DG21;F8WAL6;Q9NYB9-3;Q9NYB9-2;Q9NYB9-4;Q9NYB9;H7C3Q7;E9PEZ7 H0Y6B5 ABI2 Abl interactor 2 1 HT(0.006)PPT(0.026)IGGS(0.966)LPY(0.002)R;HTPPT(0.125)IGGS(0.875)LPYR;HTPPT(0.086)IGGS(0.914)LPYR 89.74700000000001 0.00463 12727600.0 91419.0 69675.0 97237.0 72031.0 71846.0 72634.0 59551.0 62576.0 76652.0 52996.0 True False 90115.34829580861 69513.67181831936 89242.54920567453 77328.4000283721 67620.15953467069 69527.61313812378 62634.25939471913 65483.50940491926 68018.644578656 62156.28798726883 1.4498186943574638 1.1183690993992033 1.4357766864062675 1.2440961732497748 1.0879053708696536 1.1185933940000532 1.0076898319209184 1.053529924733149 1.094316388272542 1.0 15.923612727209699 -6.213873141698892 2.858744189305845 1.0590779684931697 1.3167788490319354 0.6540083152500527 0.09116381723669466 0.16978859222313453 2.758110766600386 0.02750929633467649 0.03566563552022435 6.111205083795485e-07 6.213873141698892 0.2577008805387657 HTPSPGLPAEGAPEAPRPS(ph)SPPPEVLEPHSLDQPPATSPR ddPTM_PC-9_AZD4547_30min_R2 1 HTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPR 40 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 HTPSPGLPAEGAPEAPRPS(0.496)S(0.496)PPPEVLEPHS(0.008)LDQPPATSPR 72.539 1.454e-07 8456400.0 6453.5 1742.3 10403.0 13179.0 10461.0 12549.0 6239.2 11879.0 7547.7 9751.2 True False 8505.578758861137 2305.4644024665113 10265.049422800545 10140.785163520273 9008.670720003922 11764.30904621671 6794.476713068044 10043.373502264041 7946.656013065056 9409.813456034279 0.9039051410107095 0.24500638755894513 1.0908876643264191 1.0776818489443316 0.9573697461799188 1.250217031526013 0.7220628490473332 1.0673297137281161 0.8445072848887417 1.0 13.199950407326646 -5.28370834261875 24.936175352493052 1.003743932883108 0.5744556898588838 0.42037859548381473 0.20044749918152852 579.0134938314752 648362.6769101189 0.048766918154535724 0.10164076647586805 5.203453254184159e-06 5.28370834261875 -0.4292882430242241 HTPSPGLPAEGAPEAPRPS(ph)SPPPEVLEPHSLDQPPATSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPR 40 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 HT(0.001)PS(0.005)PGLPAEGAPEAPRPS(0.496)S(0.496)PPPEVLEPHS(0.001)LDQPPATSPR;HTPS(0.001)PGLPAEGAPEAPRPS(0.495)S(0.495)PPPEVLEPHS(0.008)LDQPPATSPR 62.405 1.0334000000000001e-05 10450500.0 15279.7 22216.3 18761.8 18403.1 25168.5 14811.9 17991.2 11801.7 13264.6 9828.8 True False 17866.251422168767 24421.787441588272 19209.152466522733 17372.033970655193 20236.913098588975 14035.13788914028 16286.94329099176 11491.917879934766 13458.56968084225 11610.683635262005 1.5387768699431625 2.1033892756683636 1.6544376773977325 1.4962111204111865 1.7429562060522297 1.2088123602399374 1.4027548939089003 0.9897709937624566 1.1591539399082547 1.0 13.503165299915356 -6.915434541839781 0.6529718512555628 1.0064949288940168 1.8205556837897672 0.6969170197093976 0.18421841254667953 0.4032785510977922 0.3681975429796907 0.14279890753506946 0.13105027721792428 1.2149697305346046e-07 6.915434541839781 0.8140607548957504 HTPSPGLPAEGAPEAPRPS(ph)SPPPEVLEPHSLDQPPATSPR ddPTM_PC-9_Lapatinib_30min_R1 1 HTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPR 40 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 HTPSPGLPAEGAPEAPRPS(0.5)S(0.5)PPPEVLEPHSLDQPPATSPR 84.53 1.9905e-14 6902200.0 2982.2 5283.2 8760.3 4982.1 5236.8 7141.7 8271.1 8016.0 8312.6 7879.2 True False 2939.6732811314996 5270.967074998843 8040.061949735913 5348.500253798393 4928.781719944932 6836.266139115827 8699.337087196878 8388.45262384672 7376.34745244138 9241.109221625935 0.3181082714888934 0.5703825102146599 0.870032131091001 0.578772539694899 0.5333539082527728 0.7397668369850751 0.941373689950422 0.9077322237698655 0.7982101797021659 1.0 13.173850315144767 -7.021792940351892 3.566279690624788 0.9021039877853376 0.5915015911551414 0.5829348890628775 0.1339199266962223 0.1967334778093527 5.293305755228665 0.05517685273569503 0.04437504763526372 9.5105812390048e-08 7.021792940351892 -0.3106023966301962 HTPSPGLPAEGAPEAPRPSS(ph)PPPEVLEPHSLDQPPATSPR ddPTM_PC-9_AZD4547_30min_R2 1 HTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPR 40 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 HT(0.001)PS(0.005)PGLPAEGAPEAPRPS(0.358)S(0.635)PPPEVLEPHS(0.001)LDQPPATSPR 57.985 2.9015999999999998e-05 9565200.0 26631.0 35036.0 39909.0 44579.0 43108.0 41380.0 37369.0 47758.0 40787.0 39878.0 True False 35099.10404078885 46360.70183367774 39379.78058392262 34302.00028868427 37123.19829824389 38792.5020585264 40694.76860665464 40378.09846966291 42942.91755168921 38481.883357918545 0.9120942370292381 1.2047409790856285 1.0233329854896334 0.8913804963661124 0.9646928647686608 1.0080718164887825 1.0575045984146392 1.0492755277621872 1.1159255682025422 1.0 15.231891787925559 -7.258572386304824 5.179298031382531 1.0602073717471292 1.0041770019232343 0.09201495878761201 0.08378893149823596 0.5055159430066684 45.31473741525863 0.03593405635993422 0.02576044559984076 5.513502980665425e-08 7.258572386304824 -0.056030369823894866 HTQFWR ddPTM_PC-9_AZD4547_30min_R2 1 HTQFWR 6 0 P12236 P12236 SLC25A6 ADP/ATP translocase 3;ADP/ATP translocase 3, N-terminally processed 0 81.71600000000001 0.021214 0.0 4465.5 2137.5 5319.1 4857.5 4664.8 3779.5 5454.5 5809.5 4280.3 3727.0 False True 5885.436111829921 2828.4050739092972 5248.565258561798 3737.6784226268846 4017.173040309181 3543.1672675253885 5939.9399332333705 4911.775264029204 4506.547919594359 3596.5188644105106 1.63642575882737 0.7864285384119314 1.4593459554735484 1.0392489414175534 1.1169614818543758 0.9851657675389764 1.6515803634487427 1.365702627792075 1.2530305246523452 1.0 11.812385455990615 -7.232109845138123 24.992526824192087 1.348053835801369 1.1578506764746757 0.06099109732036134 0.2694544744767122 1605.2130809607538 1367849.4854652556 0.09659333370137077 0.07480821255165147 5.859899326374927e-08 7.232109845138123 -0.1902031593266933 HTTFEQPVFS(ph)VSKQSPPISTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HTTFEQPVFSVSKQSPPISTSK 22 1 P33981-2;P33981 P33981-2 TTK Dual specificity protein kinase TTK 1 HTTFEQPVFS(0.343)VS(0.325)KQS(0.325)PPIS(0.003)T(0.004)S(0.001)K 55.575 0.005458600000000001 5888500.0 10311.0 10745.0 30214.0 37094.0 42548.0 58223.0 37252.0 40493.0 49728.0 27283.0 True False 12056.448648467067 11811.692588768881 30934.416347233087 35015.74344037062 34211.02483337361 55169.68338426634 33723.22087887554 39430.10165587994 50455.17792386681 32229.191927890843 0.3740847327305631 0.3664904976580301 0.9598259992507827 1.0864604833628584 1.061491858372276 1.711792325035708 1.046356388777212 1.2234281810136696 1.565511727279869 1.0 14.976080396174046 -5.41181957202445 1.2480547201271428 1.2891456016046974 0.23800226992778536 0.7144751694405658 0.21828890807845122 0.3179628369321625 0.8229957266134094 0.06966463766376313 0.3224016362177874 3.8741856483200765e-06 5.41181957202445 -1.051143331676912 down HTTFEQPVFSVS(ph)KQSPPISTSK ddPTM_PC-9_AZD4547_30min_R2 2 HTTFEQPVFSVSKQSPPISTSK 22 1 P33981-2;P33981 P33981-2 TTK Dual specificity protein kinase TTK 1 HTTFEQPVFS(0.028)VS(0.485)KQS(0.485)PPIS(0.001)T(0.001)S(0.001)K;HTTFEQPVFS(0.015)VS(0.484)KQS(0.484)PPIS(0.004)T(0.006)S(0.007)K 69.986 0.00080666 31563000.0 28188.8 21741.7 150311.0 337270.0 235464.0 202625.0 81430.0 207374.0 102763.0 192451.0 True False 37152.252036535945 28769.279342883623 148317.77792853743 259517.61226955656 202773.88800449352 189954.82671843655 88677.11224918734 175329.11328045328 108194.8423851776 185713.34906752515 0.20005159684577886 0.15491228545139826 0.7986382167638862 1.3974095754161229 1.0918649037488692 1.022838840999896 0.47749455111567907 0.9440846022151258 0.5825905511285464 1.0 17.502717994294677 -5.309671057252105 4.600514429459243 0.930579983582782 0.17105687358204208 0.5979055503404478 0.24303494736336934 0.13655863893609016 6.470234905697285 0.06891904596107998 0.15770243616177493 4.90149927513682e-06 5.309671057252105 -0.75952311000074 HTTFEQPVFSVS(ph)KQSPPISTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HTTFEQPVFSVSKQSPPISTSK 22 1 P33981-2;P33981 P33981-2 TTK Dual specificity protein kinase TTK 1 HTTFEQPVFS(0.009)VS(0.495)KQS(0.495)PPISTSK 93.26899999999999 7.9757e-05 9183500.0 9384.2 7741.8 40983.0 48932.0 73304.0 73412.0 40383.0 50157.0 60371.0 28380.0 True False 10972.759713601461 8510.35474022624 41960.19014889304 46190.498679684424 58940.60741716704 69562.14548556005 36557.62989239853 48840.43189573434 61253.811664288936 33525.069344043615 0.3273001347438223 0.25385047389136184 1.2516063641296564 1.3777898027790678 1.7581054587032194 2.074929205117934 1.0904565033776346 1.4568331356609647 1.8271046969563354 1.0 15.032952695786712 -5.360998985878381 2.54876263701267 1.5460793204556036 0.24394012256694791 0.7043848596467611 0.3105223130103074 0.15210190876380442 1.8850380405888851 0.08661304890276349 0.24148660838074937 4.35512890651108e-06 5.360998985878381 -1.3021391978886556 HTTFEQPVFSVS(ph)KQSPPISTSK ddPTM_PC-9_Lapatinib_30min_R1 1 HTTFEQPVFSVSKQSPPISTSK 22 1 P33981-2;P33981 P33981-2 TTK Dual specificity protein kinase TTK 1 HTTFEQPVFSVS(0.497)KQS(0.497)PPIS(0.003)T(0.001)S(0.002)K 80.382 0.00021237 6481900.0 37770.0 17634.0 110260.0 33640.0 66308.0 89425.0 41681.0 47023.0 126350.0 36972.0 True False 37231.39287383028 17593.169556429726 101194.84841590811 36113.99781975032 62407.893806543834 85600.50120985656 43839.03823330071 49207.86024590125 112119.13247551519 43362.56093790666 0.8586068734995621 0.4057225674844803 2.333691696872213 0.8328382143172778 1.4392114408535346 1.974064708319069 1.0109882185251085 1.1348006017533145 2.5856206379522884 1.0 15.4041623424985 -5.232804025133646 24.994822288991347 1.5116268858236117 0.6321645284739168 0.28619868049068153 0.5714938238409798 904.7801898179504 789748.9069592955 0.13860121885641952 0.3665572571447191 5.850540295196733e-06 5.232804025133646 -0.8794623573496949 HTVDDGLDIR ddPTM_PC-9_AZD4547_30min_R2 2 HTVDDGLDIR 10 0 A0A0C4DGH5;Q86VP6-2;Q86VP6 A0A0C4DGH5 CAND1 Cullin-associated NEDD8-dissociated protein 1 0 ; 166.69 9.5769e-05 6349600.0 14280.8 18042.1 20480.0 24571.0 15945.2 26301.0 18544.3 30580.0 19021.5 24147.0 False True 18821.797340907113 23873.85599250477 20208.421818605708 18906.535568165767 13731.484214186663 24656.3943122596 20194.706774930717 25854.563658492643 20026.937656838112 23301.620879774782 0.80774626958436 1.024557738523103 0.8672539100550772 0.8113828503911572 0.5892930918855196 1.0581407379115297 0.86666532251665 1.1095607379370656 0.859465432047304 1.0 14.508142692964599 HTVDDGLDIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HTVDDGLDIR 10 0 A0A0C4DGH5;Q86VP6-2;Q86VP6 A0A0C4DGH5 CAND1 Cullin-associated NEDD8-dissociated protein 1 0 ; 121.61 0.00038067 0.0 8800.4 15339.3 15891.5 13391.400000000001 18311.6 14116.4 17080.2 17524.1 14689.1 12208.3 False True 10290.13390417704 16862.08433009795 16270.413628849366 12641.123273504578 14723.573430920482 13376.111133498065 15462.239806060616 17064.11094331875 14903.900298453016 14421.568149150367 0.7135239245659477 1.1692268244137767 1.1282000307163491 0.8765429073154792 1.02094122349572 0.9275073969182821 1.0721607834978444 1.1832354683512045 1.0334451943307612 1.0 13.81594042609751 -7.410084558543325 6.887913845388772 1.0901066598307965 0.9867955467760793 0.11585458563044648 0.12838343763980464 0.5529348672797988 29.902021842714156 0.053591029927255 0.035857699988300865 3.889694040172668e-08 7.410084558543325 -0.10331111305471719 HTVDDGLDIR ddPTM_PC-9_Lapatinib_30min_R1 2 HTVDDGLDIR 10 0 A0A0C4DGH5;Q86VP6-2;Q86VP6 A0A0C4DGH5 CAND1 Cullin-associated NEDD8-dissociated protein 1 0 ; 157.97 0.00022573 6447200.0 18129.1 19759.6 24351.0 20238.7 21526.8 25807.0 22092.0 21271.1 21877.1 18522.7 False True 17870.57570953023 19713.847860226215 22348.954777578303 21727.121512324047 20260.635947317165 24703.29476905526 23235.8156630138 22259.432959968322 19413.070621923966 21724.324015053666 0.8226067562400092 0.9074550649569436 1.0287525983359393 1.000128772580838 0.9326244597197937 1.137126050593673 1.0695760036958002 1.024631788061339 0.8936098821059685 1.0 14.407023665666102 -5.012665206519607 2.4209899565481146 1.0156297007655462 0.8157836638290727 0.4765902723241324 0.0637320815662575 0.3142128309775541 3.1477963984522432 0.017755696608404783 0.10687570183914896 9.712584125848795e-06 5.012665206519607 -0.1998460369364734 HTVLIIAHR ddPTM_PC-9_Lapatinib_30min_R1 1 HTVLIIAHR 9 0 F5H7U2;Q6P2Q0;Q9NP78-7;Q9NP78-2;Q9NP78 F5H7U2 ABCB9 ATP-binding cassette sub-family B member 9 0 72.87899999999999 0.027232999999999997 0.0 66585.0 50003.0 65025.0 53024.0 63156.0 58932.0 48238.0 49113.0 62623.0 51522.0 False True 65635.48568980653 49887.221125675154 59678.89550375871 56923.56184287872 59441.28824947338 56411.615737201784 50735.527609653276 51394.9692758214 55569.73829057529 60427.509051250345 1.0861855257700455 0.825571364912036 0.9876113783400088 0.9420140385829933 0.9836792742699269 0.9335419682674233 0.8396097804829749 0.8505227185888437 0.9196099452559754 1.0 15.882917851895213 -7.011804023188151 22.57794603922017 0.889492967817791 0.9573801531082917 0.12775286299039046 0.0727543250436943 285.13396505362505 545385.4225144447 0.02533411451613036 0.020783213137118055 9.731862782126191e-08 7.011804023188151 0.06788718529050075 HTVLYIS(ph)PPPEDLLDNSR ddPTM_PC-9_AZD4547_30min_R2 1 HTVLYISPPPEDLLDNSR 18 0 O94916-2;O94916;O94916-4;O94916-5 O94916-2 NFAT5 Nuclear factor of activated T-cells 5 1 HT(0.002)VLYIS(0.998)PPPEDLLDNSR 145.73 9.0977e-05 4827700.0 27015.0 25055.0 32898.0 45320.0 38118.0 34779.0 25991.0 38185.0 31932.0 34358.0 True False 35605.208053092676 33153.53877277074 32461.75102482864 34872.17418702017 32825.973664574114 32604.263632032114 28304.148648761322 32284.38565400726 33619.860329529954 33155.136877761295 1.0738971817358038 0.9999517991737918 0.9790866237262396 1.0517879722707637 0.9900720297309957 0.983384980500603 0.8536881857286568 0.973737064426415 1.0140166349933053 1.0 15.0169447905792 -6.696490530263278 2.8349339078857425 0.9550629775188318 1.0204842282247886 0.25447696772848527 0.04776458679944073 0.366062216241699 5.985894373322532 0.017789246753209777 0.017155722423059003 2.0114510571608256e-07 6.696490530263278 0.06542125070595672 HTVLYIS(ph)PPPEDLLDNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HTVLYISPPPEDLLDNSR 18 0 O94916-2;O94916;O94916-4;O94916-5 O94916-2 NFAT5 Nuclear factor of activated T-cells 5 1 HTVLYIS(1)PPPEDLLDNSR;HT(0.035)VLY(0.025)IS(0.939)PPPEDLLDNSR 124.45 2.545e-05 6604400.0 29763.2 32733.0 39552.0 39812.0 41075.0 40119.0 40485.0 35763.7 34148.0 25778.3 True False 34801.52191000435 35982.51591513931 40495.0696817953 37581.4627122455 33026.64860935465 38015.089014536905 36649.96771398251 34824.940769772395 34647.34989833096 30451.70172908948 1.142843254528519 1.1816257835195605 1.329813027923879 1.2341334171267413 1.0845583903051765 1.2483732223812758 1.203544157894205 1.1436123038242327 1.1377804172183101 1.0 14.894235231901703 -8.81674712260205 0.686774668964453 0.9973543516337113 1.2101770660225684 0.4942540872177371 0.06188475616517133 1.0310542332649288 0.9653111267265196 0.0683948203964616 0.02506161900588774 1.5249404250339432e-09 8.81674712260205 0.21282271438885703 HTVLYIS(ph)PPPEDLLDNSR ddPTM_PC-9_Lapatinib_30min_R1 2 HTVLYISPPPEDLLDNSR 18 0 O94916-2;O94916;O94916-4;O94916-5 O94916-2 NFAT5 Nuclear factor of activated T-cells 5 1 HTVLYIS(1)PPPEDLLDNSR;HT(0.106)VLY(0.346)IS(0.548)PPPEDLLDNSR 107.39 0.00016816 5643800.0 33075.0 27464.0 33766.0 26635.0 31203.0 34806.0 29336.0 29860.0 35191.0 24620.0 True False 32603.34443478784 27400.408795383115 30989.889820529286 28593.826751755314 29367.70088745831 33317.42851674887 30854.87453784961 31247.404609289308 31227.41900234157 28875.534195912092 1.1290992649203868 0.948914351141673 1.0732230825678204 0.99024407852525 1.0170444185796534 1.1538289920698892 1.0685473151252638 1.0821411786630428 1.0814490492356825 1.0 14.817560016109812 HVAEDLGK ddPTM_PC-9_Lapatinib_30min_R1 1 HVAEDLGK 8 0 A0A2R8Y4F5;H0YFD6;P40939 A0A2R8Y4F5 HADHA Trifunctional enzyme subunit alpha, mitochondrial;Long-chain enoyl-CoA hydratase;Long chain 3-hydroxyacyl-CoA dehydrogenase 0 69.628 0.030004000000000003 0.0 22086.0 17640.0 15425.0 19149.0 15754.0 11671.0 14810.0 9404.3 19501.0 13317.0 False True 21771.049589923645 17599.15566379837 14156.81604222189 20557.28133919139 14827.380693555693 11171.85853642981 15576.789334113466 9841.258110085046 17304.592025366233 15618.825706212898 1.3938979792356283 1.1267912194447327 0.906394392799361 1.3161861029676554 0.949327495706519 0.7152815932881458 0.997308608669427 0.6300895019380596 1.1079316941530866 1.0 13.930998368784243 -6.456213445412603 6.788280148110852 0.8691658073151659 1.1598737010768612 0.3803569480304554 0.17777573015962642 0.26190633615772957 22.38239995087055 0.053488957076017064 0.06031865580552726 3.4977321955613813e-07 6.456213445412603 0.29070789376169526 HVDSLSQR ddPTM_PC-9_AZD4547_30min_R2 3 HVDSLSQR 8 0 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 SEPT9 Septin-9 0 ;; 121.09 0.00074544 1610350.0 3580.88 3279.5 6399.620000000001 15058.199999999999 6910.099999999999 6985.3 5797.46 8372.14 6321.6 4678.05 False True 4719.525353068981 4339.534240882122 6314.756857362579 11586.764636870852 5950.751892008326 6548.508086742977 6313.422708831812 7078.418135638086 6655.746870197817 4514.2728933876 1.0454674461488649 0.9612919607138879 1.398842517166449 2.566695658528502 1.3182082768467203 1.4506229998490072 1.398546977095595 1.5680084706457125 1.4743784940310094 1.0 12.140277918530085 -5.364962576089185 4.949292568482196 1.5726521891342626 1.0079137672392013 0.22847398826159337 0.38075268373725035 0.28960975571834474 10.901604203616182 0.10149224931971834 0.22004206426790462 4.315562631792816e-06 5.364962576089185 -0.5647384218950613 HVDSLSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HVDSLSQR 8 0 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 SEPT9 Septin-9 0 ;;; 93.162 0.0062369999999999995 2080500.0 2254.16 2576.37 7235.099999999999 6931.799999999999 8025.099999999999 9190.6 7271.83 8294.4 7489.35 4367.599999999999 False True 2635.7447663105904 2832.1349869638407 7407.612223269549 6543.433719198815 6452.639263662377 8708.628756873373 6582.989618909949 8076.68078864324 7598.867575291822 5159.4113060974205 0.5108615324379455 0.5489259954167267 1.4357475657184362 1.268252002213072 1.2506541697958085 1.6879113217008825 1.2759187489336499 1.5654268112135534 1.472816785572307 1.0 12.332990746778577 -5.258610072075969 23.186793298312722 1.3899409372615756 0.529893445486061 0.7739482749916069 0.18125583226176087 35.53837324465131 291231.77762863913 0.044720199024047246 0.10770907723103587 5.513024568884e-06 5.258610072075969 -0.8600474917755146 HVDSLSQR ddPTM_PC-9_Lapatinib_30min_R1 4 HVDSLSQR 8 0 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 SEPT9 Septin-9 0 ;;; 96.66799999999999 0.0050771 4019640.0 8686.7 7393.37 10704.84 9213.4 11934.5 12373.880000000001 7163.65 10831.5 14901.400000000001 8539.900000000001 False True 8562.82606505432 7376.251106012297 9824.729377077374 9890.984171001413 11232.536174129777 11844.67799732312 7534.5487449913535 11334.771032334798 13223.047413301492 10016.010336298525 0.8549138606638821 0.7364460357314521 0.9809024798498921 0.9875173685829766 1.121458125239997 1.1825744582548414 0.7522504961567152 1.1316652690799467 1.320191071027603 1.0 13.290020335762383 -5.5378784866708255 1.937048073645631 1.0749905946309923 0.7924100409659014 0.3657570369251686 0.1424394870996925 0.3920023168918196 2.8819568185407336 0.04337192113482589 0.11298038679335937 2.8981543627340852e-06 5.5378784866708255 -0.28258055366509094 HVDSLSQRS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 HVDSLSQRSPK 11 1 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 SEPT9 Septin-9 1 HVDS(0.002)LS(0.021)QRS(0.977)PK 58.595 0.033694999999999996 12312000.0 40792.0 8183.8 28984.0 17513.0 14373.0 16026.0 10564.0 11142.0 22526.0 12928.0 True False 40210.29859966336 8164.850913911172 26601.047401475484 18800.964441655375 13527.608398405231 15340.60533843066 11110.952229951024 11659.697995870789 19988.884670704036 15162.58757452282 2.6519417218224253 0.5384866450915208 1.7543870576663523 1.2399575170959602 0.892170174247515 1.011740592628593 0.7327873409034998 0.7689781139640164 1.3183029989083577 1.0 13.888228357489789 -4.75036589452863 24.999898665484025 1.0365766404264714 2.6519451917084034 0.6889159722330177 0.32722846790626237 285.29774412621333 644057.1181212523 0.08199018915747018 1.216876492353786 1.776781834734989e-05 4.75036589452863 1.615368551281932 HVEEFSPR ddPTM_PC-9_AZD4547_30min_R2 2 HVEEFSPR 8 0 Q14566 Q14566 MCM6 DNA replication licensing factor MCM6 0 ; 157.68 3.2069e-05 5134600.0 12670.1 11337.7 21554.9 29192.0 22538.0 17802.6 17362.5 23768.0 16283.1 17869.699999999997 False True 16698.928245548377 15002.38980419249 21269.067942278532 22462.235411904087 19408.987734198312 16689.400607711978 18907.728864380675 20095.201734305218 17143.7914233925 17244.08724211336 0.9683857435356972 0.8700019660973288 1.2334122208762317 1.3026050666832054 1.1255445105147606 0.9678332273194065 1.0964760615571687 1.1653386724481938 0.9941837560137182 1.0 14.073814146148912 -5.249453362666245 24.900958878385353 1.118356361397107 0.9191938368715814 0.3525927433001026 0.1033669056584306 801.5844298201832 1665284.3286620912 0.02798935580911424 0.07284948261208979 5.630495780316645e-06 5.249453362666245 -0.19916252452552563 HVEEFSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HVEEFSPR 8 0 Q14566 Q14566 MCM6 DNA replication licensing factor MCM6 0 111.95 0.0031371 2101900.0 11232.0 11914.0 16100.0 17756.0 16980.0 16643.0 12962.0 16615.0 11842.0 11096.0 False True 13133.355757887892 13096.743183117027 16483.885059590008 16761.1888857287 13652.89089194989 15770.211781672957 11734.145523246663 16178.87385504767 12015.16684713704 13107.61696411233 1.0019636516573556 0.999170422737781 1.257580619323989 1.2787365492613627 1.041599775865474 1.203133401353626 0.8952157783809117 1.234310851419004 0.9166553218661838 1.0 13.6781177991624 -7.234780204941558 24.94567467764891 1.0310713206906266 1.1328927476922184 0.16899168397404551 0.12606713646934775 1566.323995544348 1465651.2486075244 0.04865021079542634 0.03767106647870629 5.8239789292204535e-08 7.234780204941558 0.1018214270015918 HVEEFSPR ddPTM_PC-9_Lapatinib_30min_R1 2 HVEEFSPR 8 0 Q14566 Q14566 MCM6 DNA replication licensing factor MCM6 0 ; 157.68 3.2069e-05 6257500.0 22756.0 19988.6 21032.0 20116.8 19088.699999999997 21858.0 19291.9 20048.9 17862.8 16019.1 False True 22431.495267060684 19942.317624795924 19302.8301458678 21596.25657967754 17965.94019582814 20923.18429348666 20290.740186008334 20980.445086107848 15850.903360377004 18787.98009089097 1.1939279879233111 1.0614402148778417 1.0274031616217458 1.149471974911668 0.956246499565891 1.1136473528429438 1.079985186691035 1.1166950882750752 0.843672565315419 1.0 14.197522349474092 -1.5228787486721895 0.15049933550148245 0.9663733802256803 1.5791992581683265 0.24021148011685922 0.0846586188298857 117.52978101605848 1.162843322217292 0.294141624858704 15.729840762916567 0.029999999765699167 1.5228787486721895 0.6128258779426462 HVEVSQAPLPPAPAY(ph)LSSPLALPSQR ddPTM_PC-9_AZD4547_30min_R2 1 HVEVSQAPLPPAPAYLSSPLALPSQR 26 0 A0A087X0G7;A0A087WUW6;A0A087X1B1;Q9Y6K9-3;Q9Y6K9;Q9Y6K9-2 A0A087X0G7 IKBKG NF-kappa-B essential modulator 1 HVEVSQAPLPPAPAY(0.601)LS(0.198)S(0.198)PLALPS(0.003)QR 85.537 2.21e-06 9031500.0 15671.0 12003.0 16671.0 27714.0 18790.0 16292.0 15797.0 24995.0 22025.0 30553.0 True False 20654.052022950775 15882.735018541889 16449.931647362097 21324.965477031707 16181.332839009065 15273.25866451213 17202.90239715602 21132.59707796024 23189.196535071318 29483.348769609413 0.7005327713736635 0.5387018666927468 0.557939729842297 0.7232884447309753 0.5488295432603069 0.5180299830884667 0.5834785774025872 0.7167637992242968 0.7865184079419796 1.0 14.847612777080368 -8.451845747595959 1.3137613985449594 0.9948545482223228 0.5925460009437326 0.7798075915534369 0.06692779097305249 0.19675506101328705 0.7379502094671136 0.06460123205486036 0.019840039512732537 3.5330863541814418e-09 8.451845747595959 -0.4023085472785902 HVEVSQAPLPPAPAYLS(ph)SPLALPSQR ddPTM_PC-9_AZD4547_30min_R2 1 HVEVSQAPLPPAPAYLSSPLALPSQR 26 0 A0A087X0G7;A0A087WUW6;A0A087X1B1;Q9Y6K9-3;Q9Y6K9;Q9Y6K9-2 A0A087X0G7 IKBKG NF-kappa-B essential modulator 1 HVEVSQAPLPPAPAY(0.008)LS(0.494)S(0.494)PLALPS(0.005)QR 112.05 1.1266e-10 8599800.0 7422.7 7999.3 13738.0 17735.0 11764.0 13402.0 7397.7 14382.0 11121.0 9883.6 True False 9782.964198248792 10584.917290162639 13555.825143750268 13646.469753018599 10130.77166142111 12563.970821371935 8056.080968756169 12159.592365482054 11708.833356028517 9537.578172333708 1.0257283370559303 1.1098118514894082 1.421306845282019 1.4308107893263542 1.0621953999609794 1.3173124869180195 0.8446673592804704 1.2749140448205394 1.2276526749728893 1.0 13.219407261340683 HVEVSQAPLPPAPAYLS(ph)SPLALPSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HVEVSQAPLPPAPAYLSSPLALPSQR 26 0 A0A087X0G7;A0A087WUW6;A0A087X1B1;Q9Y6K9-3;Q9Y6K9;Q9Y6K9-2 A0A087X0G7 IKBKG NF-kappa-B essential modulator 1 HVEVSQAPLPPAPAYLS(0.499)S(0.499)PLALPS(0.002)QR 110.44 2.1496999999999998e-10 6547800.0 8756.2 6880.0 9403.0 9379.9 11895.0 14079.0 9421.3 9998.3 11787.0 9181.2 True False 10238.451717166836 7563.000931664017 9627.203181076076 8854.374613046104 9564.26013897197 13340.672455336993 8528.846259694781 9735.855219074525 11959.362576186808 10845.678881660797 0.944012064978179 0.6973284949872954 0.8876533489623164 0.8163965307896185 0.8818498356192707 1.2300449424051303 0.7863819639834995 0.8976713514482807 1.1026845536067977 1.0 13.404832740402101 -6.536728193741772 24.999453559821575 0.9914609180615703 0.8324624233830343 0.2907557580445963 0.12418875239852929 318.65605755924673 575197.8933637672 0.040465829905058634 0.04048427796482372 2.9058407263495554e-07 6.536728193741772 -0.158998494678536 HVEVSQAPLPPAPAYLS(ph)SPLALPSQR ddPTM_PC-9_Lapatinib_30min_R1 2 HVEVSQAPLPPAPAYLSSPLALPSQR 26 0 A0A087X0G7;A0A087WUW6;A0A087X1B1;Q9Y6K9-3;Q9Y6K9;Q9Y6K9-2 A0A087X0G7 IKBKG NF-kappa-B essential modulator 1 HVEVSQAPLPPAPAY(0.005)LS(0.483)S(0.483)PLALPS(0.028)QR;HVEVSQAPLPPAPAY(0.021)LS(0.478)S(0.478)PLALPS(0.023)QR 121.91 2.0353e-12 15166200.0 30373.0 21518.8 33654.0 21997.1 28499.3 28712.1 22640.8 21976.2 29838.0 23564.8 True False 29939.875450273958 21468.974540711137 30887.09802819679 23614.84011417447 26823.027205779603 27484.15041417415 23813.029841714782 22997.294480062425 26477.330231930544 27637.94428187772 1.0832887983606516 0.7767934663211694 1.1175613393377288 0.8544354773035268 0.9705145553595872 0.9944354085768813 0.8616064059919628 0.8320913540281581 0.9580064986704458 1.0 14.754362691200537 -7.260027314878006 24.914764063890836 0.898933679229279 0.9595632704015749 0.051702223081774856 0.10277610156313362 341.60504183031156 6027419.202557922 0.038111823328561015 0.027857675444042336 5.495063116641858e-08 7.260027314878006 0.06062959117229583 HVFGESDELIGQK ddPTM_PC-9_AZD4547_30min_R2 2 HVFGESDELIGQK 13 0 P60174;P60174-3;P60174-4;U3KPZ0;U3KQF3;U3KPS5 P60174 TPI1 Triosephosphate isomerase 0 ; 144.1 4.5837e-06 18901000.0 226262.0 220114.0 372630.0 553480.0 489690.0 458790.0 335870.0 473010.0 351320.0 406740.0 False True 298208.60945803707 291261.54593612667 367688.68272788305 425883.737180757 421704.99616468046 430101.7887731109 365761.779333594 399917.17318847653 369890.0579660045 392500.15640202083 0.7597668551056448 0.7420673372618994 0.9367860795226678 1.085053675098521 1.0744072054145792 1.0958002990770184 0.9318767734679834 1.0188968505247136 0.9423946766205672 1.0 18.582333703321012 -5.387322416133919 3.3571394163835975 1.023273304286081 0.7486910816846158 0.8007241277274132 0.05309176790871498 0.104478374277067 2.1569333024125754 0.015342323331176175 0.036263958855678534 4.098996843359052e-06 5.387322416133919 -0.27458222260146525 HVFGESDELIGQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HVFGESDELIGQK 13 0 P60174;P60174-3;P60174-4;U3KPZ0;U3KQF3;U3KPS5 P60174 TPI1 Triosephosphate isomerase 0 ;; 162.68 6.7538e-05 33226000.0 285987.0 364168.0 396280.0 512035.0 544457.0 476679.0 467236.0 395317.0 399439.0 350859.0 False True 334398.9505992775 400320.1923375328 405728.8181002688 483347.3389898686 437774.5592672763 451681.11409457884 422976.02358429844 384940.3476229843 405280.03971065406 414466.9593016835 0.8068169080659434 0.9658675639959674 0.9789171585205797 1.1661902792064256 1.056235121865595 1.0897879890247362 1.0205301389933505 0.9287600349894061 0.9778343740439333 1.0 18.660897571208366 -4.731742965154479 1.788159793186119 1.0329901474049268 0.7142282069913746 0.5335150558547925 0.06250539494156948 0.8711070305430121 2.586215337360631 0.018890773932380988 0.4944760613167209 1.8546289507954883e-05 4.731742965154479 -0.3187619404135522 HVFGESDELIGQK ddPTM_PC-9_Lapatinib_30min_R1 3 HVFGESDELIGQK 13 0 P60174;P60174-3;P60174-4;U3KPZ0;U3KQF3;U3KPS5 P60174 TPI1 Triosephosphate isomerase 0 ;; 151.13 4.5829e-05 66127100.0 720380.0 616803.0 862350.0 720910.0 768830.0 787870.0 713710.0 674920.0 793510.0 603465.0 False True 710107.2490984859 615374.8305497624 791450.9117672653 773928.1262852604 723608.930977937 754174.6367146734 750662.4115901495 706279.2471165971 704136.5477692602 707773.1211834329 1.0032978476367544 0.8694521056702805 1.1182268555832113 1.0934692249844316 1.0223741327842824 1.0655598724258626 1.0605975122861455 0.9978893320159744 0.9948619503830661 1.0 19.43292744858808 -5.259885320829181 24.999105294649187 1.0463866678979679 0.9363749801418516 0.42929038096719074 0.049638495890745295 121.48106146621353 1954142.7751456827 0.012895736886889013 0.03056518345684653 5.496860039840865e-06 5.259885320829181 -0.11001168775611625 HVGNQQYNVTYVVK ddPTM_PC-9_Lapatinib_30min_R1 1 HVGNQQYNVTYVVK 14 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;A0A0A0MT44 O75369-2 FLNB Filamin-B 0 67.01899999999999 0.029613999999999998 4468000.0 80423.0 88782.0 104740.0 83201.0 102240.0 92009.0 80993.0 84910.0 103300.0 79754.0 False True 79276.15327222817 88576.43073374979 96128.68150809218 89319.87909039989 96226.44421157375 88073.98955345484 85186.42123820736 88855.22857919488 91665.26620277586 93539.37263447515 0.8475164098225939 0.9469427497646461 1.0276814864232124 0.9548907222142293 1.0287266367243972 0.9415713092028376 0.9107012249386287 0.9499232898045559 0.979964517839747 1.0 16.513286132230114 -4.792198679593442 3.9809943091278557 0.971127079449316 0.8377801697019829 0.5285752376559665 0.03568279290443869 0.18633600829635064 5.476072978442157 0.009370633191880506 0.06996893543088566 1.613620194354175e-05 4.792198679593442 -0.1333469097473331 HVIPMNPNTDDLFK ddPTM_PC-9_Lapatinib_30min_R1 2 HVIPMNPNTDDLFK 14 0 A0A0A0MSQ0;P13797-3;P13797-2;P13797;U3KQI3 A0A0A0MSQ0 PLS3 Plastin-3 0 ; 78.486 0.009427600000000001 7197900.0 72507.0 71438.0 62129.0 64782.0 68836.0 62517.0 70300.0 54258.0 65035.0 61338.0 False True 71473.03688384483 71272.58970013753 57020.993444875465 69546.28438641678 64787.20181678308 59843.293644244906 73939.79001945829 56779.02475856727 57710.0734510893 71940.19157225237 0.9935063463385644 0.9907200431702445 0.7926166472271211 0.9667236473309736 0.9005703265568141 0.8318478493922542 1.027795289441197 0.7892531770858833 0.8021951594767273 1.0 16.134510380834953 -5.145089424720138 12.023142921438383 0.8874812117938138 0.9927367242730251 0.20080847554647163 0.08235120514695844 0.9165008613587622 90.238681947975 0.020345819605259156 0.05389547767114008 7.15995965716397e-06 5.145089424720138 0.10525551247921128 HVLS(ph)DLEDDEVRDLGSTGTSSVQR ddPTM_PC-9_AZD4547_30min_R2 1 HVLSDLEDDEVRDLGSTGTSSVQR 24 1 H0YDJ4;H9KV85;E9PN67;C9J066;Q8N4C6-4;Q8N4C6-9;Q8N4C6-2;Q8N4C6;Q8N4C6-5;Q8N4C6-10;Q8N4C6-7 H0YDJ4 NIN Ninein 1 HVLS(1)DLEDDEVRDLGSTGTSSVQR 63.559 0.00087279 1965100.0 1090.7 605.56 3198.1 5871.1 3031.0 2887.7 1163.1 4153.4 2881.6 1478.2 True False 1437.519912030656 801.2954276287786 3155.691104398583 4517.608602590779 2610.1979688683573 2707.1316625037844 1266.6136467767403 3511.587465637126 3033.915493097004 1426.4486679290621 1.0077614037928664 0.5617415092770989 2.2122710584321683 3.167032017457386 1.829857623028159 1.897812184460893 0.8879489849541011 2.4617692487562817 2.1269012767923043 1.0 10.47821211580418 -5.261741539070446 24.99998699286752 1.9998284896076874 0.7847513839734164 0.3482206942823075 0.6333822166180376 27.60513917511957 2284231.063114364 0.16842988533410533 0.3898035196191865 5.47341604454663e-06 5.261741539070446 -1.215077105634271 HVLTGSADNSCR ddPTM_PC-9_AZD4547_30min_R2 2 HVLTGSADNSCR 12 0 Q13347;Q5TFK1 Q13347 EIF3I Eukaryotic translation initiation factor 3 subunit I 0 ; 108.72 0.0011739 9213400.0 11773.2 12534.4 21455.0 28845.0 27625.0 20912.1 16028.3 24127.0 19488.7 22345.0 False True 15516.83270222731 16585.899676448505 21170.492681552045 22195.23090080751 23789.74559220997 19604.46308115296 17454.787649068552 20398.726533304514 20518.832895030395 21562.708351288667 0.7196142733758195 0.7691937119511831 0.9818104635397908 1.0293340956624792 1.1032818885568336 0.9091837055794211 0.8094895763882736 0.9460187561311337 0.9515888524181664 1.0 14.396250776544138 -5.201226705385333 4.553015524236819 0.9641068081183536 0.7342204729315109 0.5982117069924198 0.07299943836079786 0.16352636318727146 6.964075556422672 0.021395828544719955 0.06030535968525427 6.291776610692622e-06 5.201226705385333 -0.22988633518684265 HVLTGSADNSCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HVLTGSADNSCR 12 0 Q13347;Q5TFK1 Q13347 EIF3I Eukaryotic translation initiation factor 3 subunit I 0 ;; 134.75 4.8961999999999996e-05 7406200.0 16993.6 19568.4 24085.8 25384.800000000003 31351.6 28260.100000000002 23572.1 23746.7 25580.800000000003 19246.2 False True 19870.280841100765 21511.02142894974 24660.09681790517 23962.571954631992 25208.47903934373 26778.09060693722 21339.18004077477 23123.374286708433 25954.87080588104 22735.383707164623 0.8739804481434383 0.9461472788854209 1.084657164160111 1.0539770194017286 1.1087773738078481 1.1778156441889571 0.9385889552438094 1.0170654951128686 1.1416068952336114 1.0 14.47265173233444 -5.079526823964231 2.9952924052895926 1.0667149760958554 0.8791243161260129 0.4805812671437525 0.06632416015189393 0.2340160336593299 3.881666651328487 0.017943692544954457 0.07332113681998494 8.3267049495333e-06 5.079526823964231 -0.18759065996984248 HVLTGSADNSCR ddPTM_PC-9_Lapatinib_30min_R1 3 HVLTGSADNSCR 12 0 Q13347;Q5TFK1 Q13347 EIF3I Eukaryotic translation initiation factor 3 subunit I 0 ;; 82.774 0.0098584 12893600.0 15746.099999999999 17126.2 20661.6 18467.2 16438.5 19375.6 18083.5 16709.7 21159.899999999998 17043.100000000002 False True 15521.557726518913 17086.545336130595 18962.88300408245 19825.339492773273 15471.619749334483 18546.95075472963 19019.77514675494 17486.093663758922 18776.649238374797 19988.977126496746 0.7765058526153414 0.8547983835291512 0.9486670020221226 0.9918136064347906 0.7740075768472315 0.9278589213124062 0.9515131778075295 0.8747868164089256 0.9393501788285642 1.0 14.286917028105877 -1.5228787452803376 0.10274373479609332 1.0227095767017813 0.4951661337986282 0.29176857774822396 0.06487461043734993 195.28161709535289 1.4216111727143306 0.8015568987373407 14.53593820862137 0.029999999999999995 1.5228787452803376 -0.5275434429031531 HVLVTLGEK ddPTM_PC-9_AZD4547_30min_R2 1 HVLVTLGEK 9 0 F8W1R7;G3V1V0;P60660-2;P60660;J3KND3;G8JLA2;B7Z6Z4;G3V1Y7;F8VPF3;F8VZU9;F8W180;H0YI43;F8VXL3 F8W1R7 MYL6 Myosin light polypeptide 6 0 88.681 0.0083347 4553400.0 81439.0 88367.0 99128.0 132220.0 123190.0 113940.0 98046.0 120770.0 92872.0 107570.0 False True 107334.90796356909 116929.90463913114 97813.49795091542 101738.72177863658 106087.19491418434 106815.31378802577 106771.90405973022 102107.77151851398 97781.02431805425 103804.0070417598 1.034015073429572 1.1264488527123124 0.9422901941691477 0.9801039928806181 1.0219951805088412 1.0290095424259926 1.0285913530946493 0.9836592481197433 0.9419773581449264 1.0 16.663502610114264 -5.259311537196356 24.999997956377147 0.9937942831649983 1.0802319617241036 0.4904134324149513 0.03631055862436876 159.12287190082353 1869507.611813954 0.009659677407877222 0.023022420741676486 5.504127211972737e-06 5.259311537196356 0.08643767855910534 HVLVTLGEK ddPTM_PC-9_Lapatinib_30min_R1 1 HVLVTLGEK 9 0 F8W1R7;G3V1V0;P60660-2;P60660;J3KND3;G8JLA2;B7Z6Z4;G3V1Y7;F8VPF3;F8VZU9;F8W180;H0YI43;F8VXL3 F8W1R7 MYL6 Myosin light polypeptide 6 0 105.4 0.0022149 8443600.0 185810.0 181400.0 201650.0 163100.0 192240.0 171140.0 170430.0 169660.0 172920.0 161030.0 False True 183160.31532661943 180979.97944518243 185071.11539151042 175094.91808565002 180932.8211583818 163820.7411468251 179254.0314796053 177543.0229742809 153443.92867167466 188863.8209410128 0.9698009624819848 0.9582564757159462 0.9799183055250855 0.9270961331463099 0.9580067810599465 0.8674013918101906 0.9491178913275884 0.9400584086971974 0.8124580340858363 1.0 17.526986837634887 -6.176195993885442 1.4659219329416096 0.9136661923778248 0.9677146250434439 0.15833831323118652 0.04887603148048086 0.7141105715471888 3.0753336148622292 0.01727389572066072 0.02571760076415919 6.665059121461448e-07 6.176195993885442 0.054048432665619095 HVPDS(ph)GATATAYLCGVK ddPTM_PC-9_AZD4547_30min_R2 1 HVPDSGATATAYLCGVK 17 0 P10696;P05187 P10696 ALPPL2;ALPP Alkaline phosphatase, placental-like;Alkaline phosphatase, placental type 1 HVPDS(0.699)GAT(0.262)AT(0.038)AY(0.001)LCGVK 53.924 0.032918 3962300.0 24130.0 49122.0 44332.0 43157.0 41053.0 32190.0 35632.0 52480.0 35645.0 29110.0 True False 31802.838064820524 64999.72586693452 43744.12871398579 33207.8204190033 35353.499576361835 30177.15421130894 38803.17897166952 44370.42187042818 37529.12192929025 28090.867760394423 1.1321415321195467 2.313909503307628 1.557236646696299 1.1821571587697022 1.2585406715775105 1.0742692062313572 1.3813449731296121 1.5795319051334702 1.3359901249545203 1.0 14.777813571271894 -5.539960703874059 7.709977971117977 1.2861611158598492 1.7755828995001466 0.276132449793958 0.30658802883838887 0.17291168760878373 53.26129109870589 0.0794444060146565 0.1417679450883812 2.8842924698146464e-06 5.539960703874059 0.4894217836402974 HVPDS(ph)GATATAYLCGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HVPDSGATATAYLCGVK 17 0 P10696;P05187 P10696 ALPPL2;ALPP Alkaline phosphatase, placental-like;Alkaline phosphatase, placental type 1 HVPDS(0.801)GAT(0.181)AT(0.018)AYLCGVK;HVPDS(0.969)GAT(0.015)AT(0.015)AY(0.001)LCGVK;HVPDS(0.947)GAT(0.043)AT(0.01)AYLCGVK 82.663 0.006553799999999999 9464500.0 135832.9 127386.2 118006.9 103154.4 213364.0 134403.0 113086.1 85708.2 119371.3 104942.7 True False 158826.72714793516 140032.26006993325 120820.63203966031 97374.99339907707 171556.8558462897 127354.67007704082 102373.76593553637 83458.45056534454 121116.87943418763 123967.98078404367 1.281191531421461 1.1295841005418494 0.9746115995075685 0.7854850323706372 1.3838803758943805 1.0273190647421844 0.8258081263247714 0.6732258607223096 0.9770013084683314 1.0 16.91960801497484 -7.170298102137003 4.715068432556676 0.8422904898016247 1.0958369507968193 0.2923046521939785 0.17402779143102898 0.28595351224079124 10.797401356600574 0.06999296466486189 0.05339758599971546 6.756190675269792e-08 7.170298102137003 0.2535464609951946 HVPDS(ph)GATATAYLCGVK ddPTM_PC-9_Lapatinib_30min_R1 1 HVPDSGATATAYLCGVK 17 0 P10696;P05187 P10696 ALPPL2;ALPP Alkaline phosphatase, placental-like;Alkaline phosphatase, placental type 1 HVPDS(0.932)GAT(0.053)AT(0.014)AY(0.001)LCGVK 83.54 0.0037438000000000003 5099400.0 34446.0 33380.0 13457.0 7165.1 9529.9 11060.0 9544.0 10961.0 14595.0 4243.4 True False 33954.793723377246 33302.71066086107 12350.617405522195 7692.045356072916 8969.370018504274 10586.989582119246 10038.141620849347 11470.288075097791 12951.157407836523 4976.866036024913 6.822525154905993 6.691502326926279 2.481605354880476 1.545560057352207 1.8022124673599262 2.1272402161291066 2.0169603819328317 2.304721081915891 2.602271653303487 1.0 12.281021838692563 -5.279978312120291 4.300411639859086 1.9818246403182866 6.853346374945598 0.9550082132855563 0.41560412380120604 0.03403414067880795 1.5719588320448625 0.10820692901036696 0.265834897969733 5.248336688380565e-06 5.279978312120291 4.871521734627311 HVQVAVAHVS(ph)ET(ph)ITQLNLSGYRK ddPTM_PC-9_AZD4547_30min_R2 1 HVQVAVAHVSETITQLNLSGYRK 23 1 D6R9R7;A0A0A0MTL5;Q13309-2;Q13309;Q13309-4 D6R9R7 SKP2 S-phase kinase-associated protein 2 2 HVQVAVAHVS(1)ET(1)IT(0.001)QLNLSGYRK 66.138 0.0058467 2192300.0 6983.6 5444.4 9591.0 9983.7 8478.3 9224.3 5452.5 10049.0 6209.0 7218.2 True False 9204.239532096168 7204.195828955217 9463.817073351927 7682.112211627384 7301.234391110723 8647.503062795187 5937.761937107881 8496.1579530475 6537.195064075268 6965.49301504909 1.321405320802163 1.034269335047843 1.3586715330709767 1.1028813315913206 1.0482006622268167 1.2414775298908607 0.8524539360357156 1.2197496910400134 0.9385114664463126 1.0 12.76600975453012 -6.402274109941027 0.46739047523531213 1.0009568884762803 1.2572564704403457 0.272889675838745 0.13570468730514085 1.9737262181664978 0.8470168742140824 0.11548902825142554 0.23273405593559912 3.960279977461728e-07 6.402274109941027 0.25629958196406544 HVS(ph)PVTPPR ddPTM_PC-9_AZD4547_30min_R2 2 HVSPVTPPR 9 0 Q13443 Q13443 ADAM9 Disintegrin and metalloproteinase domain-containing protein 9 1 HVS(1)PVTPPR;HVS(0.999)PVT(0.001)PPR 98.898 0.002445 18665500.0 8868.6 18909.300000000003 24547.0 30817.0 28246.0 15686.2 22202.0 25879.0 19925.0 22764.0 True False 11688.63032166047 25021.361433484482 24221.49074127513 23712.616767903797 24324.53046145024 14705.339434278792 24177.934989026922 21879.995190259368 20978.19482230631 21967.03928882235 0.5320985758698981 1.1390411381572156 1.1026288259792902 1.0794634841833084 1.1073194772236543 0.669427465437339 1.1006460484335527 0.9960375134118654 0.9549850822628062 1.0 14.423052816394398 -4.752379800525556 24.99020081637566 1.0157553110456647 0.5320976371665603 0.5590120664678224 0.12910021842338582 275.6830030483314 760396.2592697517 0.03276186948035826 0.39269275782701724 1.7685616339545025e-05 4.752379800525556 -0.4836576738791044 HVS(ph)PVTPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HVSPVTPPR 9 0 Q13443 Q13443 ADAM9 Disintegrin and metalloproteinase domain-containing protein 9 1 HVS(0.805)PVT(0.195)PPR;HVS(0.987)PVT(0.013)PPR;HVS(1)PVTPPR 105.13 0.0015055 25364200.0 32373.5 34515.0 42975.0 37116.0 69644.0 43589.0 36964.0 37678.0 43059.0 37790.0 True False 37853.694144229295 37941.4210983116 43999.68698359507 35036.51085169557 55997.75814363707 41303.116105951005 33462.50232381497 36688.99242314091 43688.656415375255 44641.02785452461 0.8479574947867742 0.8499226590829053 0.9856333758035426 0.7848500031377399 1.2544011828339072 0.9252277129583321 0.7495907673287 0.8218671071531405 0.9786660055800479 1.0 15.446082624986122 -5.181062690421597 0.007582239994589777 1.8060692045197626 1.310772232863131e-06 0.025265996285304015 0.13717111841943241 75041.49338787468 101.5305879620791 11518.033600299868 12683.077777275617 6.590787503398576e-06 5.181062690421597 -1.8060678937475299 HVS(ph)PVTPPR ddPTM_PC-9_Lapatinib_30min_R1 2 HVSPVTPPR 9 0 Q13443 Q13443 ADAM9 Disintegrin and metalloproteinase domain-containing protein 9 1 HVS(1)PVTPPR;HVS(0.999)PVT(0.001)PPR 92.866 0.0037959000000000005 16004700.0 51601.0 60379.0 36287.0 19849.6 27629.0 19984.1 21540.7 22738.0 33825.0 10481.5 True False 50865.160277535506 60239.196135174694 33303.62293187071 21309.405800324483 26003.91654070397 19129.426628212394 22655.97204654543 23794.49048915004 30015.272306959254 12293.213309279145 4.137661895050788 4.9001993717708485 2.709106406437487 1.7334284587935809 2.115306705129385 1.556096534481603 1.8429658280999879 1.9355794038967435 2.441613234214619 1.0 13.58557444899741 -5.428363393059364 3.3612178391286176 1.8559824102964968 4.516573038874719 0.8751966859926456 0.40399329000204204 0.07261046881535702 1.5314482774108014 0.10460055392832224 0.23911291192119472 3.7293797380135705e-06 5.428363393059364 2.660590628578222 HVTLPS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HVTLPSSPR 9 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;A0A0A0MSW0;X6RE05 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 HVTLPS(0.677)S(0.323)PR 100.04 0.0022377 33590000.0 22046.0 27699.0 40650.0 35829.0 47819.0 38020.0 35296.0 28787.0 43334.0 28773.0 True False 25777.952371652103 30448.773663686305 41619.250165983474 33821.61728918524 38449.21022156371 36026.1642696152 31952.507359089184 28031.371752347713 43967.67777012638 33989.317133057324 0.7584133647269126 0.8958336392722772 1.224480327246864 0.9950661014101698 1.1312145540037575 1.0599260976201512 0.9400750016249317 0.8247112362573759 1.2935734365596978 1.0 15.05279375706163 -5.019325387248454 6.7397704438440735 1.0495767802702638 0.7891178957056205 0.3605547296253204 0.12879662515369075 0.1487649858182992 32.01758347690605 0.03210932504034508 0.09856842161561491 9.564771796238698e-06 5.019325387248454 -0.2604588845646433 HVTLPS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 2 HVTLPSSPR 9 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;A0A0A0MSW0;X6RE05 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 HVTLPS(0.598)S(0.402)PR;HVTLPS(0.574)S(0.426)PR 111.94 0.0012477 129398000.0 97553.0 74931.0 115798.0 78138.0 104087.0 108445.0 80661.0 87092.0 116005.0 58486.0 True False 96161.87633097082 74757.50187324677 106277.53543320633 83884.5291807269 97964.8073029155 103807.06014764209 84837.23190269589 91138.6122649776 102939.2953131947 68595.22717230373 1.401874157941378 1.089835327543476 1.549343005545397 1.2228916302007151 1.428157779211644 1.5133277405276329 1.2367803912886537 1.3286436392439862 1.5006772272161506 1.0 16.065820577312024 -10.545792627024671 5.242740494239513 0.9999972979932851 1.3583403591099166 0.3800065976522099 0.1391519235391206 4.194047738052949e-06 7.813255990853028e-07 0.1285758275882789 0.031183983614345285 2.8458196446580024e-11 10.545792627024671 0.3583430611166315 HVTLPSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 HVTLPSSPR 9 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;A0A0A0MSW0;X6RE05 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 HVTLPS(0.228)S(0.772)PR;HVTLPS(0.195)S(0.805)PR;HVTLPS(0.202)S(0.798)PR;HVTLPS(0.428)S(0.572)PR 117.95 0.0010356 315419000.0 88723.0 91066.0 210967.0 285867.0 210987.0 187220.0 150945.0 233979.0 160497.0 183390.0 True False 116935.06844695666 120501.30360730944 208169.43973661072 219964.779751123 181695.09695071873 175513.10380370484 164378.8125807883 197822.921852533 168980.54375888067 176969.57191957178 0.6607636961460285 0.6809153816684048 1.1763007475161802 1.2429525446956013 1.0267024719554307 0.9917699517489432 0.9288535356546737 1.1178357935026173 0.9548564870557412 1.0 17.43314179963513 -5.24924622450614 24.52949969196607 1.0580688866173293 0.6708394294581251 0.7282580896600842 0.09382786514098035 314.0772429498296 631839.0159503018 0.025885873079839587 0.06734006178682557 5.63318190404668e-06 5.24924622450614 -0.3872294571592042 HVTLPSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 HVTLPSSPR 9 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;A0A0A0MSW0;X6RE05 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 HVTLPS(0.2)S(0.8)PR;HVTLPS(0.041)S(0.959)PR;HVTLPS(0.177)S(0.823)PR;HVTLPS(0.342)S(0.658)PR;HVTLPS(0.322)S(0.678)PR 117.95 0.0010356 196403000.0 204344.0 256880.0 359005.0 368897.0 381394.0 352184.0 338630.0 304024.0 334275.0 246713.0 True False 238935.40322203026 282381.34873922326 367565.0407340434 348228.89707021025 306662.58355973696 333714.8510555016 306552.51493110746 296043.6921400544 339163.1394888298 291440.11392096634 0.8198439123820324 0.9689172329098126 1.2612026388162916 1.194855754018282 1.0522318957194023 1.145054627401084 1.051854224206896 1.0157959663038578 1.1637489943501915 1.0 18.152839938565023 -4.99549747573625 4.854960429489286 1.1120272324682667 0.8438588841470969 0.5743303512256607 0.07931246047541184 0.1215268246476008 8.252502114624825 0.020724872416512562 0.07786778722809772 1.0104213734157107e-05 4.99549747573625 -0.26816834832116987 HVTLPSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 HVTLPSSPR 9 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;A0A0A0MSW0;X6RE05 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 HVTLPS(0.21)S(0.79)PR;HVTLPS(0.227)S(0.773)PR 125.36 0.00080992 143916000.0 145687.0 101532.0 152944.0 94147.0 123925.0 138531.0 106376.0 116383.0 148921.0 75963.0 True False 143609.47666427642 101296.90889210746 140369.5347009132 101070.88444518519 116635.97514592428 132606.3520615335 111883.62877823459 121790.57905702996 132147.9487723484 89093.10333566491 1.611903405398474 1.1369781172675488 1.5755376055547252 1.1344411706526047 1.3091470695154657 1.488401987322511 1.2558057199635833 1.3670034435569594 1.4832567710036 1.0 16.443026137126843 -10.98516995984691 3.1411549665736374 0.9925719727878174 1.3633747351125656 0.32840842269665427 0.15967905540144464 30099332.386195607 39041175.590156116 1976741.218886041 0.03678280026861545 1.0347371461445457e-11 10.98516995984691 0.3708027623247482 HVTSNAS(ph)DSESSYR ddPTM_PC-9_AZD4547_30min_R2 2 HVTSNASDSESSYR 14 0 Q12959-3;Q12959;Q12959-5;A0A590UK48;Q12959-8;C9JUA9;A0A590UJ64 Q12959-3 DLG1 Disks large homolog 1 1 HVTSNAS(0.622)DS(0.345)ES(0.03)S(0.003)YR;HVT(0.001)S(0.007)NAS(0.623)DS(0.335)ES(0.031)S(0.003)YR 148.18 4.482e-08 0.0 4358.4 2348.5 8063.2 10095.2 11703.900000000001 10058.7 7509.9 12127.5 7280.0 9839.6 True False 5744.280539648309 3107.6066975794065 7956.2766995987095 7767.907609285214 10079.015509019588 9429.727898890753 8178.266551395961 10253.473537225947 7664.805937585435 9495.118598941153 0.6049719632031644 0.3272846637140426 0.837933367202591 0.8180948482467034 1.061494430426972 0.9931132297749612 0.861312733082445 1.0798678742537626 0.8072364613160465 1.0 13.212970305156468 -5.428023274700515 3.4158992912126105 0.9485564475469397 0.4672485272305686 0.7413494682372843 0.1109303566220805 0.10942767092396825 2.3741120198262395 0.028750044788952274 0.06543767406071133 3.7323015511730374e-06 5.428023274700515 -0.4813079203163711 HVTSNAS(ph)DSESSYR ddPTM_PC-9_Lapatinib_30min_R1 1 HVTSNASDSESSYR 14 0 Q12959-3;Q12959;Q12959-5;A0A590UK48;Q12959-8;C9JUA9;A0A590UJ64 Q12959-3 DLG1 Disks large homolog 1 1 HVTSNAS(0.755)DS(0.231)ES(0.007)S(0.007)YR 130.47 1.9376e-05 3400000.0 4112.3 3152.0 7578.6 5977.2 5857.5 5446.5 4561.2 6448.5 6851.5 4256.4 True False 4053.6578478965403 3144.701737658301 6955.516762241993 6416.783227354686 5512.973366288083 5213.565891411616 4797.356617876997 6748.120851406639 6079.811920506472 4992.113068703504 0.8120124268237601 0.6299339967624187 1.3933011265004065 1.285384192834635 1.104336638697138 1.0443605382451053 0.9609871715351418 1.3517564122719652 1.2178834567313703 1.0 12.285434895506976 -5.251129084944411 24.997888301405467 1.1721733431763433 0.7209731662605 0.6079084450312331 0.1441565918768622 476.1990742598722 1154565.801932891 0.03846823070451306 0.09938030582681515 5.608812410455108e-06 5.251129084944411 -0.45120017691584324 HVTSNASDS(ph)ESSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HVTSNASDSESSYR 14 0 Q12959-3;Q12959;Q12959-5;A0A590UK48;Q12959-8;C9JUA9;A0A590UJ64 Q12959-3 DLG1 Disks large homolog 1 1 HVT(0.006)S(0.279)NAS(0.076)DS(0.624)ES(0.006)S(0.01)YR;HVT(0.001)S(0.015)NAS(0.127)DS(0.835)ES(0.011)S(0.011)YR 94.67299999999999 0.015198 0.0 4057.7 7154.7 9482.1 9451.2 11105.6 10360.8 8337.5 8661.5 9768.3 9064.2 True False 4744.588466771876 7864.971332234968 9708.189225064498 8921.67990520382 8929.537402216654 9817.46140885401 7547.711641727284 8434.144802617839 9911.142907692 10707.467707832284 0.44311022888271806 0.7345314080641037 0.906674620924905 0.8332203419747698 0.8339541753354893 0.916879852149612 0.7049016488003316 0.7876880914101139 0.9256290262208505 1.0 13.386329705826224 -4.805160656488266 2.78709376276872 0.8497536716243123 0.379416899032164 0.721777208368495 0.07879985264473881 0.21360273737644564 2.372754459265471 0.019908254756994058 0.22810438390169374 1.566171596537949e-05 4.805160656488266 -0.47033677259214823 HVTSNASDS(ph)ESSYR ddPTM_PC-9_Lapatinib_30min_R1 1 HVTSNASDSESSYR 14 0 Q12959-3;Q12959;Q12959-5;A0A590UK48;Q12959-8;C9JUA9;A0A590UJ64 Q12959-3 DLG1 Disks large homolog 1 1 HVTSNAS(0.299)DS(0.695)ES(0.003)S(0.003)YR 132.51 0.00024039 0.0 1399.3 2073.1 4600.3 3593.2 3684.8 4206.7 3732.3 3436.4 5208.0 3329.0 True False 1379.3457253998079 2068.299864320885 4222.081091671529 3857.455914563815 3468.067308595533 4026.7892472966596 3925.540231715847 3596.06768919497 4621.420197328714 3904.413214386327 0.35327862335815946 0.5297338551923655 1.081361234029921 0.9879732760739842 0.888242898015246 1.0313430024412944 1.0054110608097715 0.9210264108175802 1.183640138369699 1.0 11.930890029878256 -5.149862905596827 3.854201495651209 1.0047565881902925 0.38854381287729034 0.8912474220580542 0.08050835692807065 0.06563924184809732 1.694315991398153 0.020537216781867294 0.06385856834618506 7.081692979889848e-06 5.149862905596827 -0.6162127753130021 down HVVFGK ddPTM_PC-9_AZD4547_30min_R2 1 HVVFGK 6 0 P23284;H0YEL5;C9JQD4;O43447-2;O43447;P45877;P62937;P62937-2 P23284;P62937 PPIB;PPIH;PPIC;PPIA Peptidyl-prolyl cis-trans isomerase B;Peptidyl-prolyl cis-trans isomerase;Peptidyl-prolyl cis-trans isomerase H;Peptidyl-prolyl cis-trans isomerase C;Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed 0 81.297 0.021809000000000002 0.0 46988.0 40037.0 52688.0 78036.0 62691.0 51057.0 45732.0 61381.0 42946.0 52747.0 False True 61929.206588884634 52978.17728379251 51989.32269427238 60046.00584418149 53987.4367754293 47864.39771875741 49802.05940537692 51895.9768450601 45216.037884003315 50900.343584937305 1.216675610166432 1.0408216045808791 1.0213943371034009 1.1796778099146392 1.0606497515157352 0.9403551007251294 0.9784228533206719 1.0195604428182568 0.8883248068561934 1.0 15.635387774290738 -6.613215126742937 4.803068776371961 0.9680596439189012 1.1046898633971136 0.5523069722587737 0.06345812264343481 0.17430056257543045 6.969954683520752 0.02115506215802607 0.021166227101170998 2.4366035535866527e-07 6.613215126742937 0.1366302194782124 HVVFIAQR ddPTM_PC-9_AZD4547_30min_R2 1 HVVFIAQR 8 0 P62081;B5MCP9;A0A2R8Y623 P62081 RPS7 40S ribosomal protein S7 0 111.04 0.0031494 13452000.0 35595.0 23648.0 42130.0 54512.0 43054.0 45641.0 35324.0 53414.0 36974.0 37248.0 False True 46913.46957800608 31291.753538155346 41571.328672747026 41945.10060200449 37076.695266136056 42787.0610549348 38467.7675683446 45160.093631613054 38928.37015608297 35943.958857408805 1.3051837101225767 0.8705705919120108 1.1565595441966265 1.166958285491102 1.0315139579705415 1.1903825403504624 1.070215101262158 1.2564028856911684 1.0830295658448046 1.0 15.133461695170048 -6.772388265439676 24.988432213834823 1.1329192391648784 1.099247028293238 0.0 0.12239228007581528 1276.448629207991 2913202.1810454335 0.04064675576637956 0.03618861930758749 1.6889303287740867e-07 6.772388265439676 -0.033672210871640296 HVVFIAQR ddPTM_PC-9_Lapatinib_30min_R1 1 HVVFIAQR 8 0 P62081;B5MCP9;A0A2R8Y623 P62081 RPS7 40S ribosomal protein S7 0 94.262 0.0056967 12334000.0 30588.0 27991.0 27772.0 31880.0 25624.0 30353.0 24324.0 21306.0 26553.0 20578.0 False True 30151.80951084778 27926.188559261915 25488.69336302017 34224.56154856241 24116.8466987223 29054.872946298878 25583.37770175395 22295.954541377047 23562.32152451408 24134.87988153854 1.249304312217098 1.1570883591023569 1.0560936490310524 1.4180539417037559 0.9992528165499578 1.203854052264158 1.0600167818246904 0.9238063189380884 0.976276726470786 1.0 14.55883202610657 -7.483764921372079 3.27509148718783 0.9632149200615598 1.1763505284913975 0.44807037844037556 0.10697308796453098 0.22850224951120293 4.966309591705668 0.050527490440811465 0.029951149214246606 3.2827293541026345e-08 7.483764921372079 0.2131356084298377 HWDQNER ddPTM_PC-9_AZD4547_30min_R2 3 HWDQNER 7 0 F5GZS6;J3KPF3;P08195-2;P08195-3;P08195;P08195-4;F5GZI0 F5GZS6 SLC3A2 4F2 cell-surface antigen heavy chain 0 ;; 134.81 0.0033149 29585600.0 27018.9 39220.8 61800.5 54535.200000000004 40499.3 34981.3 37005.3 48805.1 27094.100000000002 18393.1 False True 35610.34817196764 51898.15659545347 60980.984990270634 41962.952200440894 34876.67126380411 32793.91378105194 40298.70001123491 41263.393224627194 28526.23881229857 17749.163167423932 2.0063113869686755 2.9239776605752974 3.4357104284326243 2.364221445519073 1.9649755278499714 1.847631545877076 2.2704563382006344 2.3248078140585404 1.6071878174321157 1.0 14.115463385988308 -8.523882055226112 0.23132566927790213 0.6221879536490977 2.977039814787813 0.5463538552232186 0.4312968978595961 2.6151772627871765 0.49164031355442234 2.243525836022525 1.3854122819412622 2.9930773798456118e-09 8.523882055226112 2.3548518611387155 HWDQNER ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 HWDQNER 7 0 F5GZS6;J3KPF3;P08195-2;P08195-3;P08195;P08195-4;F5GZI0 F5GZS6 SLC3A2 4F2 cell-surface antigen heavy chain 0 ;;;;; 134.81 0.0033149 51867900.0 79919.2 77371.5 77842.7 61394.7 145773.7 77661.50000000001 70139.5 67878.1 64444.9 48522.50000000001 False True 93447.942083849 85052.43118957 79698.76518808387 57954.954003302955 117210.38993026127 73588.79422474283 63495.37879399476 66096.37179779189 65387.28474472736 57319.24514610134 1.630306572350334 1.4838372517429248 1.3904364055203318 1.0110906704298226 2.0448697401981315 1.2838409514495863 1.1077497380182002 1.1531270453635334 1.140756208112325 1.0 15.806731990001794 -6.995074981964427 24.99963743776774 1.1249725551768817 1.4947848298544748 0.39122801308416366 0.241430030912479 157.90322034236326 801518.3911415911 0.0854131545231138 0.07507157374129839 1.0114048177624701e-07 6.995074981964427 0.36981227467759314 HWDQNER ddPTM_PC-9_Lapatinib_30min_R1 3 HWDQNER 7 0 F5GZS6;J3KPF3;P08195-2;P08195-3;P08195;P08195-4;F5GZI0 F5GZS6 SLC3A2 4F2 cell-surface antigen heavy chain 0 ;; 110.12 0.0079832 30164900.0 68362.0 73122.0 30564.6 24556.9 34724.799999999996 23405.6 23328.199999999997 19790.9 54483.5 11351.5 False True 67387.14534394443 72952.69050160224 28051.696570767912 26362.896345416942 32682.355535583516 22404.597049118453 24536.02005024074 20710.45746423256 48346.99449331012 13313.591650077013 5.061530135149866 5.479564975329572 2.1069969177404992 1.9801490866113838 2.454811323238569 1.6828364304675705 1.8429301945804242 1.5555875535744528 3.6314013351183454 1.0 13.700612203748612 -5.264387852141924 24.74796225058903 2.0457303666869997 5.270547782156666 0.7966414061110434 0.6545030810494121 79.73173508206692 669234.7977025964 0.16107350111243465 0.3604707750737645 5.44016594981538e-06 5.264387852141924 3.2248174154696665 HWGGNVLGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HWGGNVLGPK 10 0 P62424;Q5T8U2 P62424 RPL7A 60S ribosomal protein L7a 0 72.928 0.024578 2729700.0 47029.0 43387.0 37173.0 52059.0 50607.0 39135.0 47475.0 45521.0 45876.0 39596.0 False True 54990.08083491003 47694.174625306245 38059.345299387554 49142.30300755522 40690.92163538918 37082.6917067699 42977.82431076496 44326.1219834863 46546.84971113483 46774.44135823649 1.1756437754916522 1.019663158775659 0.8136782438062342 1.0506229808536618 0.8699392329187902 0.7927981741729564 0.9188313759133121 0.9476568975779106 0.9951342733233611 1.0 15.513432802560892 -4.898674873711322 3.450697484924671 0.9190154627753452 1.1799437476794938 0.4952691601187491 0.07795738795957642 0.21039707316554768 4.375134543082891 0.019915604378021777 0.12087611531728153 1.2627725314139375e-05 4.898674873711322 0.26092828490414866 HWGGNVLGPK ddPTM_PC-9_Lapatinib_30min_R1 1 HWGGNVLGPK 10 0 P62424;Q5T8U2 P62424 RPL7A 60S ribosomal protein L7a 0 72.928 0.024578 5192700.0 77436.0 64930.0 71014.0 72215.0 85748.0 73120.0 80285.0 73397.0 70854.0 77176.0 False True 76331.74843997663 64779.65857428734 65175.503041967204 77525.932002178 80704.4712270544 69992.82805104513 84441.76446247796 76807.29256892207 62873.67639430271 90515.76876944404 0.8432977974744263 0.7156726331219695 0.7200458431500268 0.8564908971788892 0.8916067589573221 0.7732666805197929 0.9328956226131451 0.8485515133231722 0.6946157255146395 1.0 16.465881525820024 -5.772794632925404 24.940076970319073 0.8516084394943009 0.7552721475491168 0.21452783215977167 0.08461819465553615 309.8610034127564 680562.0323268967 0.023073262146683874 0.034563659938263394 1.6873507430237198e-06 5.772794632925404 -0.09633629194518412 HWGGQADFR ddPTM_PC-9_AZD4547_30min_R2 2 HWGGQADFR 9 0 Q6PJG6 Q6PJG6 BRAT1 BRCA1-associated ATM activator 1 0 ; 126.31 5.9223e-06 0.0 5004.2 3953.5 7349.6 11565.1 8521.0 8287.6 5390.8 6644.299999999999 3856.6 7594.200000000001 False True 6595.431506173841 5231.391560093758 7252.139501856666 8898.94487401383 7338.006233166375 7769.375061871517 5870.570756636625 5617.576105824811 4060.4520025950555 7328.329369494582 0.8999911403584624 0.7138586840638352 0.9896033783695546 1.2143210853836894 1.00132047335537 1.0601836612602134 0.8010789991336736 0.7665561716165388 0.5540760789897596 1.0 12.839268631036067 -7.4070198202659565 4.782908513139213 0.7516726232176592 0.9792715817269421 0.28147254444426173 0.15506748665733608 0.30131809241714214 10.549763864703646 0.07155224446342422 0.046906917974161605 3.917239992591322e-08 7.4070198202659565 0.2275989585092829 HWILPQDYDHAQAEAR ddPTM_PC-9_AZD4547_30min_R2 4 HWILPQDYDHAQAEAR 16 0 Q15293;Q15293-2 Q15293 RCN1 Reticulocalbin-1 0 ;;; 100.11 0.00076574 28200500.0 71586.0 65404.1 96280.0 126820.0 94415.0 91401.0 75366.5 90466.0 81332.3 86658.0 False True 94348.85891870037 86544.69627811517 95003.26429176547 97583.60834946806 81307.1069715294 85685.68102105772 82073.97249574366 76486.55840187041 85631.35933481861 83624.12979664248 1.1282492164419329 1.034924925240776 1.1360747731880119 1.1669312265104859 0.9722924133172133 1.0246525880679243 0.9814627990190331 0.9146469875127042 1.0240029946267581 1.0 16.351631672513108 -6.273758353270899 24.856189386468962 0.983596779220997 1.1121100086108187 0.6900167274629901 0.04274507544244156 421.7996633461545 851070.3250188415 0.013628969132666523 0.015563939862840357 5.324044131548355e-07 6.273758353270899 0.12851322938982168 HWILPQDYDHAQAEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HWILPQDYDHAQAEAR 16 0 Q15293;Q15293-2 Q15293 RCN1 Reticulocalbin-1 0 ; 128.73 8.3827e-06 14258700.0 32486.0 31416.0 41355.0 36982.0 43527.0 40343.0 37831.0 34018.0 40302.0 24548.0 False True 37985.23817225301 34534.77285888908 42341.060039710865 34910.018437261686 34998.19681118393 38227.34206020742 34247.37380727853 33125.06354505036 40891.34050610681 28998.358078138903 1.3099099635192477 1.190921664110491 1.4601192221166024 1.2038618994631778 1.2069027052110288 1.3182588461457065 1.1810107908522145 1.1423082457217628 1.4101260628591836 1.0 14.823683594976307 -13.182872291506799 0.3445325576693718 9.976899925640832e-34 1.2734415546841074 0.38256305358638554 0.10056213271758818 157.10360729343782 3.1746807711660696 113.31791567710033 0.07751076162291798 6.563382405367334e-14 13.182872291506799 1.2734415546841074 HWILPQDYDHAQAEAR ddPTM_PC-9_Lapatinib_30min_R1 2 HWILPQDYDHAQAEAR 16 0 Q15293;Q15293-2 Q15293 RCN1 Reticulocalbin-1 0 ; 137.73 5.804199999999999e-06 12247000.0 77239.0 63386.0 59959.0 52411.0 55586.0 54658.0 45769.0 50905.0 68235.0 47280.0 False True 76137.55769610216 63239.23361142419 55029.40246843321 56265.47977797069 52316.54076628078 52320.40475402113 48138.694870563064 53270.23213783902 60549.65575359541 55452.285003360055 1.37302831959925 1.1404261088175591 0.9923739385148651 1.014664765835373 0.9434514874023808 0.9435211687101956 0.8681102116467548 0.9606499017057851 1.0919235474232756 1.0 15.758959289802888 -4.6029252157844285 1.2264072345508543 0.963153647729209 1.7028734629633173 0.8360090779340895 0.05465514506365808 0.8118507226563749 0.7947888644813148 0.017096795395775344 0.8468563827795424 2.4950243257077096e-05 4.6029252157844285 0.7397198152341083 HWMLDK ddPTM_PC-9_Lapatinib_30min_R1 1 HWMLDK 6 0 P62701;C9JEH7;Q8TD47;P22090 P62701 RPS4X;RPS4Y1;RPS4Y2 40S ribosomal protein S4, X isoform;40S ribosomal protein S4, Y isoform 2;40S ribosomal protein S4, Y isoform 1 0 92.69200000000001 0.019030000000000002 0.0 64004.0 71210.0 73728.0 60730.0 69542.0 67822.0 63676.0 61075.0 61994.0 56873.0 False True 63091.291223103864 71045.11762012949 67666.36843831014 65196.28678934114 65451.67628483237 64921.41116080397 66972.83171093925 63912.76746524937 55011.58289423892 66703.42227149091 0.9458478901774299 1.0650895441461363 1.0144362333149852 0.9774054249268418 0.9812341564490682 0.9732845624706639 1.0040389148003803 0.9581632439354725 0.8247190477024581 1.0 16.025473161460816 -8.010009572249436 15.670839573289852 0.9053851804850966 0.9949179262883572 0.30613357063097624 0.04921077752621578 3.5922609422649887 5616.659849499402 0.028013132222981647 0.01207058702454848 9.7721568198689e-09 8.010009572249436 0.08953274580326054 HWPFMVVNDAGRPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HWPFMVVNDAGRPK 14 1 P11142;E9PKE3;P11142-2;E9PN89;E9PNE6;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PPY6;E9PN25 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 ; 77.64399999999999 0.010185 12961800.0 126613.0 129406.0 135392.0 153630.0 179085.0 166208.0 169304.0 171617.0 140808.0 120980.0 False True 148046.08017926096 142252.57246553974 138620.2587570195 145022.60917518046 143994.57982242934 157491.75988753833 153266.2994651871 167112.2355932421 142867.05061743583 142912.7163228466 1.035919573768494 0.995380789937436 0.969964481284295 1.0147635067516843 1.0075700996203778 1.1020136201998776 1.0724468991195386 1.1693307628113907 0.9996804643660429 1.0 17.124774767075472 -6.746081926901237 21.008641069026943 1.0795120102279823 1.0028277979775255 0.28878074971768 0.0486973868450888 38.048502711149645 52048.27332209645 0.015364676990489984 0.015271652981591688 1.7943950936418122e-07 6.746081926901237 -0.07668421225045674 HWPFQVINDGDKPK ddPTM_PC-9_AZD4547_30min_R2 1 HWPFQVINDGDKPK 14 1 A0A0G2JIW1;P0DMV9;P0DMV8 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 55.291000000000004 0.033895 4891400.0 61777.0 58781.0 66845.0 83663.0 68118.0 70313.0 73161.0 72114.0 64339.0 70288.0 False True 81420.8009585751 77780.80872489464 65958.59162425283 64375.78793046491 58660.99150226815 65916.31699471174 79672.18726836305 60970.43831486393 67739.82818932821 67827.23851400224 1.2004145051809327 1.1467488641578352 0.9724499046299276 0.949114092521623 0.8648589090083358 0.971826635417333 1.1746341000144882 0.8989078672615753 0.9987112799136592 1.0 16.04957713635453 -5.187948090023008 3.6678034761721237 0.9762376045944471 1.1888659312026009 0.5067171625188023 0.07747055273983669 0.1969126828021454 5.098669405068113 0.021219704744343745 0.06474674582948468 6.487119676000858e-06 5.187948090023008 0.21262832660815378 HWVAPGGPYSAETPGVPS(ph)PIAALK ddPTM_PC-9_AZD4547_30min_R2 2 HWVAPGGPYSAETPGVPSPIAALK 24 0 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 HWVAPGGPYSAET(0.001)PGVPS(0.999)PIAALK;HWVAPGGPYSAETPGVPS(1)PIAALK 159.5 9.2851e-08 28121000.0 70222.0 65398.0 116340.0 132249.0 124863.0 105167.0 82153.0 118415.0 86636.0 110912.0 True False 92551.13529166293 86536.62457240715 114797.25558479434 101761.036276682 107527.92774226633 98590.8908648876 89464.45784855077 100116.68265599737 91215.40208910055 107029.0046389853 0.8647294778069083 0.8085343301500367 1.07258080155012 0.9507799929554382 1.0046615691229115 0.9211604947410291 0.8358898426675955 0.9354163667474665 0.8522493729318992 1.0 16.707642291421934 -10.059704980098868 15.135516584911652 1.0000001827704956 0.9196185336457298 0.09563273644779946 0.07665139609429761 0.0 0.0 0.07714193910261102 0.018709668416766505 8.715554438648122e-11 10.059704980098868 -0.08038164912476586 HWVAPGGPYSAETPGVPS(ph)PIAALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HWVAPGGPYSAETPGVPSPIAALK 24 0 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 HWVAPGGPYSAETPGVPS(1)PIAALK;HWVAPGGPYSAETPGVPS(1)PIAALK 124.73 4.8599e-08 31018000.0 64959.0 57933.0 60130.0 80728.0 92979.0 83529.0 80784.0 77703.0 75347.0 60863.0 True False 75955.27570126766 63684.205374141275 61563.72724429488 76205.07188370728 74760.43240533612 79148.59219559931 73131.55469448828 75663.37858313374 76448.80733248066 71896.98010875707 1.0564459812689169 0.8857702406666803 0.8562769555990907 1.059920343920335 1.039827156749109 1.1008611498824135 1.017171438687184 1.0523860455429328 1.0633104090997723 1.0 16.13364355391892 -5.780986606718564 24.999870233996454 1.0504448379186573 0.9281249749774815 0.47889298313281925 0.05476109282872829 183.0796122824029 234148.55201437423 0.015254649170215817 0.022663459732817404 1.6558210268285845e-06 5.780986606718564 -0.1223198629411758 HWVAPGGPYSAETPGVPS(ph)PIAALK ddPTM_PC-9_Lapatinib_30min_R1 2 HWVAPGGPYSAETPGVPSPIAALK 24 0 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 HWVAPGGPYSAETPGVPS(1)PIAALK;HWVAPGGPYSAETPGVPS(1)PIAALK 114.91 1.2061e-08 17904700.0 97249.0 75175.0 104018.0 83964.0 89953.0 98654.0 87010.0 88647.0 102983.0 83954.0 True False 95862.21142671742 75000.9369062383 95466.04156109126 90138.99265569312 84662.14139440241 94434.79839370622 91514.95205680028 92765.86324178384 91383.9700809337 98465.33703832662 0.9735630254269484 0.7616988796478192 0.9695395804508554 0.9154388271743532 0.8598167024142571 0.9590664210792114 0.9294128757328991 0.9421169523410627 0.9280826413600091 1.0 16.587328318493064 -8.934345445867436 0.1531768798703756 1.0577207951850087 0.849800498153819 0.1899031616867891 0.05863798692579771 14.664432352926864 1.157830351542357 0.903572946608985 0.48158641730283347 1.1632004301929599e-09 8.934345445867436 -0.20792029703118975 HY(ph)MAYAASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HYMAYAASR 9 0 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 HY(0.953)MAY(0.047)AASR;HY(0.921)MAY(0.079)AASR 94.40700000000001 0.0060347000000000005 349370000.0 4029.9 0.0 5193.2 3828.7 4530.4 20586.0 13922.0 14393.0 7464.3 4067.3 True False 4712.082475846904 0.0 5317.025583320674 3614.190351812879 3642.7006417485163 19506.433920418174 12603.207373448544 14015.199000644068 7573.451266431764 4804.669293270916 0.980729825140373 0.0 1.1066371603904828 0.7522245822151925 0.7581584536630291 4.059891062166864 2.6231165152406466 2.9169955610207716 1.5762690008735067 1.0 12.230221417975903 -6.665037633908325 11.030003248168839 2.5659096074059384 0.6973484518380397 0.5270014845043611 0.8079831175292643 0.2883461516186931 30.842656022951086 0.2571105823276962 0.257035675169323 2.162531120875628e-07 6.665037633908325 -1.8685611555678987 HY(ph)NMHKK ddPTM_PC-9_AZD4547_30min_R2 1 HYNMHKK 7 1 Q86V15-2;Q86V15 Q86V15-2 CASZ1 Zinc finger protein castor homolog 1 1 HY(1)NMHKK 54.525 0.039538 0.0 2656.6 974.79 2586.7 2838.7 2481.3 2650.2 3461.5 2507.3 3367.8 2809.4 True False 3501.343539287285 1289.8718044425943 2552.3986678802453 2184.281572477805 2136.814325355679 2484.482575048494 3769.5667941859606 2119.854397022192 3545.815032500033 2711.043761114807 1.291511258323436 0.4757842064165673 0.9414819135308516 0.8056976445041256 0.7881887987219361 0.9164302733449242 1.3904485232786796 0.7819329320418229 1.3079150854584363 1.0 11.404632685714423 -7.016950614771374 24.314221854279527 1.1092644075016085 0.8417786822402492 0.20396846565506443 0.2424741227316861 772.3395950954714 1107853.8473209308 0.08446974643559624 0.06713722771541365 9.617216330828352e-08 7.016950614771374 -0.2674857252613593 HY(ph)YNCDFKMCY(ph)KLT(ph)SVVMEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HYYNCDFKMCYKLTSVVMEK 20 2 Q5T8C6;Q13042-4;Q13042-3;Q13042-2;Q13042;A0A3B3ISD2 Q5T8C6 CDC16 Cell division cycle protein 16 homolog 3 HY(0.508)Y(0.508)NCDFKMCY(0.964)KLT(0.51)S(0.511)VVMEK 40.52 0.034718 21757000.0 1549.0 1368.7 1803.6 2386.8 1110.2 5320.7 1877.8 1623.6 2344.9 1336.3 True False 1811.2151058554439 1504.5754905768233 1846.60466419109 2253.075334110006 892.6642796373833 5041.673125442967 1699.9211899053064 1580.9822203463975 2379.1897263850396 1578.5606118550206 1.1473839472828498 0.9531312762255896 1.1698028256394168 1.427297322123311 0.5654925588117792 3.1938419643692515 1.076880530996951 1.0015340611397439 1.5071893397803537 1.0 10.624393941412977 HYCDSEKPR ddPTM_PC-9_AZD4547_30min_R2 2 HYCDSEKPR 9 1 Q9UGI8-2;Q9UGI8;H7BYK1 Q9UGI8-2 TES Testin 0 ; 71.223 0.016021 21704000.0 45966.0 45516.0 65664.0 66927.0 71274.0 68228.0 57905.0 64391.0 58426.0 72095.0 False True 60582.2318478052 60228.1568861079 64793.252455904636 51498.01416184246 61378.835378793556 63961.69237431454 63058.43282315124 54440.85050797906 61514.27908095696 69570.97599401014 0.8707974982702723 0.8657080919964868 0.9313259089750754 0.7402226780069363 0.8822477261793495 0.9193732222445961 0.9063899409515311 0.7825224489112567 0.8841945682385305 1.0 16.08619793960829 -6.491496323363515 24.956143642533263 0.8871097138004004 0.8527291980626024 0.08576916450129524 0.06665879318386873 2215.471193593348 1761804.2781566575 0.02077807208634025 0.02353556832925465 3.224806619666672e-07 6.491496323363515 -0.03438051573779799 HYCDSEKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 HYCDSEKPR 9 1 Q9UGI8-2;Q9UGI8;H7BYK1 Q9UGI8-2 TES Testin 0 ;; 77.318 0.010468 14268600.0 52671.0 61433.5 65099.2 67790.5 71151.0 71935.0 71440.4 65932.0 65542.0 52226.5 False True 61587.16000033056 67532.21188014274 66651.41181809087 63992.41806476634 57209.472311727215 68162.60196566985 64673.04812829436 64201.35486072846 66500.42775671819 61694.751025253485 0.9982560748988373 1.0946184360562508 1.08034169374974 1.0372425044485931 0.9272988602921777 1.1048363245321937 1.0482747244059996 1.0406291263652065 1.0778944181085615 1.0 15.912860129994355 -10.882420339888128 14.5909558349956 0.9999973835554109 1.0459240634904945 0.07057600271000708 0.04949907138325479 6.592908319895342e-11 6.323066141874797e-19 0.04814846199742276 0.011677717325083051 1.3109304766703896e-11 10.882420339888128 0.04592667993508359 HYCDSEKPR ddPTM_PC-9_Lapatinib_30min_R1 2 HYCDSEKPR 9 1 Q9UGI8-2;Q9UGI8;H7BYK1 Q9UGI8-2 TES Testin 0 ; 77.318 0.010468 20479100.0 34010.0 32842.0 40422.0 27873.0 42027.0 36168.0 35419.0 33274.0 37372.0 32042.0 False True 33525.01116332987 32765.95636680645 37098.65919343229 29922.873401602246 39555.05448826109 34621.178951725924 37252.822513502004 34820.03151270906 33162.771815393375 37580.417006718766 0.8920872580348469 0.8718891107820446 0.9871806155530328 0.7962358000511949 1.0525443206548053 0.9212558483727368 0.9912828403910954 0.9265472361970811 0.8824482125747677 1.0 15.197693455093669 -6.262630797990566 24.99999866297821 0.9580660607710006 0.8929462958624881 0.258335406096049 0.06207383954599508 174.28554979242253 3657089.713918513 0.018228305576307842 0.021840811374396377 5.462220175081258e-07 6.262630797990566 -0.06511976490851257 HYEDGYPGGSDNY(ph)GSLSR ddPTM_PC-9_AZD4547_30min_R2 1 HYEDGYPGGSDNYGSLSR 18 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 HYEDGYPGGS(0.001)DNY(0.883)GS(0.107)LS(0.01)R 106.31 0.00056018 11602000.0 25999.0 35874.0 92917.0 197230.0 136570.0 71914.0 34412.0 109690.0 63024.0 75417.0 True False 34266.14118720548 47469.56894569454 91684.85986911069 151761.67067312408 117609.61286979598 67417.20621162072 37474.601335122694 92739.9309254432 66355.31997395399 72776.67378514825 0.47083961666572177 0.6522635135240517 1.259811078200459 2.085306496984952 1.6160344620448555 0.9263573437094724 0.5149259973842092 1.274308457669151 0.9117663191072537 1.0 16.15118849471184 -6.941462044980551 24.997014332191082 0.9156096288106763 1.239627735780872 0.09103799230598952 0.45712608641803937 211.7169560075778 90406.5538866501 0.1824321958340823 0.1608900727221341 1.1442948807114633e-07 6.941462044980551 0.32401810697019573 HYEDGYPGGSDNY(ph)GSLSR ddPTM_PC-9_Lapatinib_30min_R1 2 HYEDGYPGGSDNYGSLSR 18 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 HYEDGYPGGSDNY(0.843)GS(0.12)LS(0.038)R;HYEDGYPGGS(0.005)DNY(0.676)GS(0.316)LS(0.004)R 130.64 7.1711e-05 12886400.0 68213.0 57860.0 72088.0 28577.5 70135.0 56650.2 47755.0 44853.4 72503.0 36875.7 True False 67240.27011126769 57726.02872490781 66161.20290772726 30679.18468174536 66009.79719071525 54227.40300406616 50227.520232990435 46937.45270938708 64336.94864956298 43249.61561121834 1.5547021438457944 1.3347177289116645 1.5297523913846296 0.7093516149953392 1.5262516500515035 1.253823929709108 1.1613402691135624 1.0852686676182197 1.487572727302457 1.0 15.400399690142663 HYEDGYPGGSDNYGS(ph)LSR ddPTM_PC-9_AZD4547_30min_R2 7 HYEDGYPGGSDNYGSLSR 18 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 HYEDGYPGGSDNYGS(0.961)LS(0.039)R;HYEDGYPGGS(0.001)DNY(0.001)GS(0.802)LS(0.196)R;HYEDGYPGGS(0.002)DNY(0.372)GS(0.624)LS(0.002)R;HYEDGYPGGSDNYGS(0.999)LS(0.001)R;HYEDGYPGGSDNYGS(0.998)LS(0.002)R;HYEDGYPGGS(0.001)DNY(0.001)GS(0.792)LS(0.206)R;HYEDGYPGGSDNYGS(1)LSR 292.35 8.705899999999998e-121 689637600.0 145283.0 162163.0 215186.0 288969.0 292110.0 278305.0 200801.0 258289.0 224391.0 237928.0 True False 191479.97192587348 214579.01847969746 212332.4930399655 222351.66157654548 251555.56868562772 260902.54435471646 218671.89999691836 218376.36994075935 236251.85015669398 229598.21313964718 0.8339784935931132 0.9345848800190153 0.9248002854047465 0.9684381186420898 1.0956338259158207 1.1363439670849234 0.9524111577641802 0.9511239959343132 1.0289794808333281 1.0 17.808751888642917 -5.782252662638081 2.2312640749306314 1.026431986688256 0.891303166336836 0.49324442849138717 0.059005600474611564 0.29259841875233145 2.9732330752588734 0.019687252332872978 0.036599541668998016 1.651001003991086e-06 5.782252662638081 -0.13512882035142004 HYEDGYPGGSDNYGS(ph)LSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 HYEDGYPGGSDNYGSLSR 18 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 HYEDGYPGGSDNYGS(1)LSR;HYEDGYPGGSDNYGS(0.993)LS(0.007)R;HYEDGYPGGSDNY(0.419)GS(0.535)LS(0.046)R;HYEDGYPGGSDNYGS(1)LSR;HYEDGYPGGS(0.039)DNYGS(0.949)LS(0.012)R;HYEDGYPGGSDNYGS(0.999)LS(0.001)R;HYEDGYPGGSDNYGS(0.769)LS(0.231)R 271.73 4.2710999999999997e-79 222412800.0 131492.2 137355.1 179668.3 187090.69999999998 231597.2 175973.2 166517.2 144756.8 162938.7 136560.09999999998 True False 153751.23237066856 150990.80657976848 183952.27366782178 176608.6146352335 186217.39119441118 166744.85560888634 150743.48533587164 140957.0873825079 165321.37023776432 161317.3651208428 0.953097840740788 0.9359860698608691 1.1403129076031162 1.0947898541668843 1.1543542820384884 1.033644800012558 0.934452935199814 0.873787439293451 1.0248206701982898 1.0 17.299542221208576 -7.173278835147538 4.902750148920011 0.9480043460774933 1.0589254365649925 0.2647321986714879 0.07605012691533548 0.2995594577397464 12.200334891834052 0.03224235261814086 0.024634486224960506 6.709979059923386e-08 7.173278835147538 0.11092109048749921 HYEDGYPGGSDNYGS(ph)LSR ddPTM_PC-9_Lapatinib_30min_R1 3 HYEDGYPGGSDNYGSLSR 18 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 HYEDGYPGGSDNYGS(1)LSR;HYEDGYPGGSDNYGS(0.961)LS(0.039)R;HYEDGYPGGSDNYGS(0.995)LS(0.005)R 278.07 9.277699999999998e-92 143086000.0 159479.0 120766.0 131094.0 114095.0 110622.0 109587.0 84151.0 88232.0 131231.0 73929.0 True False 157204.80021513317 120486.37374684063 120315.95735747415 122485.9269097625 104115.43145121976 104900.21946977402 88507.92702599471 92331.5808267522 116450.3828563067 86707.52914579978 1.8130467072910286 1.3895722197808371 1.387606803501013 1.4126331140609587 1.2007657521430275 1.209816731063608 1.0207640316582836 1.0648623220654287 1.3430250406570108 1.0 16.403869653154437 -1.5228787452815407 0.35171277873085277 1.0883343801148773 8.952200230182136 0.7657470258139882 0.11165566319050492 30.12247741118871 0.4234674835164891 0.0947391127374296 157.34363408736635 0.029999999999916892 1.5228787452815407 7.863865850067259 HYELYR ddPTM_PC-9_AZD4547_30min_R2 4 HYELYR 6 0 B1AMS2;Q14141-2;Q14141-4;Q14141;H0Y961;D6RDU5;Q9NVA2-2;Q92599-3;Q9P0V9-3;E7EW69;E7EX04;B5ME97;Q9P0V9;Q9P0V9-2;D6RGI3;D6RER5;Q9NVA2;F8W8I8;A0A087X142;A6NMH6;A6NFQ9;Q92599-2;Q92599-4;Q92599 B1AMS2;E7EW69;D6RGI3;F8W8I8 SEPT6;SEPT11;SEPT8;SEPT10 Septin-6;Septin-11;Septin-8;Septin-10 0 ;;; 155.81 1.8964e-11 16479100.0 10849.910000000002 9196.34 20432.800000000003 28108.4 18391.899999999998 17312.8 12517.9 21971.3 19217.31 16781.329999999998 False True 14299.955687852336 12168.877060769597 20161.847721445647 21628.44265045095 15838.50215230286 16230.227879141023 13631.968849614452 18576.140435246558 20233.09777368407 16193.820744539322 0.883050140756584 0.7514518811055158 1.2450334012894624 1.3355984972072896 0.9780583842539892 1.0022482115355005 0.8418006512892428 1.1471128851114751 1.249433230913515 1.0 13.983155792545208 -5.250751101773784 24.810919330133398 1.0965240877312297 0.817250985186949 0.3771814916888887 0.1452357056739404 738.2193845868462 1713634.5428392591 0.04023571480170338 0.10406010274868872 5.613696100276491e-06 5.250751101773784 -0.2792731025442806 HYELYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HYELYR 6 0 B1AMS2;Q14141-2;Q14141-4;Q14141;H0Y961;D6RDU5;Q9NVA2-2;Q92599-3;Q9P0V9-3;E7EW69;E7EX04;B5ME97;Q9P0V9;Q9P0V9-2;D6RGI3;D6RER5;Q9NVA2;F8W8I8;A0A087X142;A6NMH6;A6NFQ9;Q92599-2;Q92599-4;Q92599 B1AMS2;E7EW69;D6RGI3;F8W8I8 SEPT6;SEPT11;SEPT8;SEPT10 Septin-6;Septin-11;Septin-8;Septin-10 0 ;;; 146.66 0.0012246 18526100.0 14692.099999999999 11146.25 13055.3 11264.0 13902.2 14086.9 20140.0 16411.5 16670.100000000002 10636.0 False True 17179.18234779778 12252.776037000014 13366.587864500963 10632.914598380714 11178.163707777734 13348.158165429833 18232.193399026986 15980.715514421605 16913.868675769216 12564.222605470328 1.367309612957522 0.9752116324065515 1.0638611145492833 0.8462851170554123 0.8896820805221074 1.0623942749643889 1.451119895877114 1.2719223477832822 1.3461930122445538 1.0 13.617033788696466 -7.106417355982462 6.749424826263897 1.288682451854768 1.0134588286048598 0.30976930589358476 0.16910400789502447 0.27284305238596 15.060631014077316 0.06428435258959297 0.04977943675011293 7.826771303490999e-08 7.106417355982462 -0.2752236232499081 HYELYR ddPTM_PC-9_Lapatinib_30min_R1 4 HYELYR 6 0 B1AMS2;Q14141-2;Q14141-4;Q14141;H0Y961;D6RDU5;Q9NVA2-2;Q92599-3;Q9P0V9-3;E7EW69;E7EX04;B5ME97;Q9P0V9;Q9P0V9-2;D6RGI3;D6RER5;Q9NVA2;F8W8I8;A0A087X142;A6NMH6;A6NFQ9;Q92599-2;Q92599-4;Q92599 B1AMS2;E7EW69;D6RGI3;F8W8I8 SEPT6;SEPT11;SEPT8;SEPT10 Septin-6;Septin-11;Septin-8;Septin-10 0 ;;; 164.83 0.0035317 24645100.0 14889.100000000002 16271.900000000001 18670.6 14540.3 18433.4 15079.899999999998 12876.9 14455.7 16907.5 13727.0 False True 14676.778703673459 16234.22341529255 17135.575338600203 15609.642167018885 17349.183653458775 14434.967829963833 13543.602874844395 15127.36459512739 15003.19930613196 16099.693659922239 0.9116185073886894 1.0083560444199757 1.0643417011875596 0.9695614399096758 1.0776095508355512 0.8965989126797803 0.8412335762983586 0.9396057412436787 0.9318934647483489 1.0 13.974745616987747 -6.783759504553621 24.99796335742136 0.9130521216575868 1.007595622696175 0.34673036140528 0.05729703635256966 246.74878480609104 276350.3004101821 0.020002972357329958 0.017654345816329457 1.645282564693643e-07 6.783759504553621 0.09454350103858833 HYEMLANR ddPTM_PC-9_AZD4547_30min_R2 1 HYEMLANR 8 0 A0A2R8YFH5;Q15437 A0A2R8YFH5 SEC23B Protein transport protein Sec23B 0 71.37899999999999 0.018973 0.0 1313.3 1095.6 1122.1 2197.5 2181.5 1605.9 1135.8 3079.1 2086.8 3077.4 False True 1730.9020816630255 1449.7312743742816 1107.2202208328843 1690.900326036558 1878.636380430987 1505.4828191345473 1236.8839996638494 2603.295845679028 2197.1039877133644 2969.661162687659 0.5828618104351312 0.48818070310156814 0.37284395766916617 0.5693916690839663 0.6326096741389674 0.5069544088228661 0.41650677700361655 0.8766305996078502 0.7398500594340197 1.0 11.536082614072876 -7.768970427640707 24.999896494796012 0.8561803800677534 0.510693357388012 0.7604928580495194 0.09303055494880967 88.41700169986304 293501.4514429507 0.050360875459921225 0.024935188197975824 1.70227441720547e-08 7.768970427640707 -0.3454870226797414 HYEMLANR ddPTM_PC-9_Lapatinib_30min_R1 1 HYEMLANR 8 0 A0A2R8YFH5;Q15437 A0A2R8YFH5 SEC23B Protein transport protein Sec23B 0 64.265 0.037307 689900.0 2967.8 841.02 1753.6 1866.8 3226.5 1150.6 2434.2 2979.6 1252.3 2598.3 False True 2925.478627772137 839.072669862115 1609.4257770917532 2004.0906994622424 3036.723613543067 1101.3915201796028 2560.230965367925 3118.043093564583 1111.2527866963808 3047.412692982878 0.9599876756136402 0.2753393630584413 0.5281285927559781 0.6576367894236839 0.9964924083093754 0.3614185642514783 0.8401326709911127 1.0231771695196854 0.3646545114336519 1.0 11.573369173528926 -14.522878744577623 0.12006354588428814 2.0465620831459534 0.5116736456650077 0.10114956235007899 0.26955124517221524 333.02413354611184 2.5820771616282467 85.21854534135274 2.542825333879794 3.0000000048541797e-15 14.522878744577623 -1.5348884374809457 HYGDQVDR ddPTM_PC-9_AZD4547_30min_R2 2 HYGDQVDR 8 0 Q9BQ52-3;Q9BQ52-4;E7ES68;G5E9D5;Q9BQ52-2;Q9BQ52 Q9BQ52-3;E7ES68 ELAC2 Zinc phosphodiesterase ELAC protein 2 0 ; 118.5 0.002938 6319400.0 3658.3 4140.9 6270.799999999999 8720.7 7739.0 6139.1 3664.4 4374.8 4845.7 6650.4 False True 4821.5633026329415 5479.364945287021 6187.645094732067 6710.277348471909 6664.573434863816 5755.221106512796 3990.5245011165757 3698.7751829029967 5101.8338093073835 6417.571520224217 0.751306516403963 0.8538066039497108 0.9641723625880032 1.0456100609592374 1.0384883773965279 0.8967911130208518 0.6218122366912328 0.576351221213 0.7949788784167902 1.0 12.647811753576976 -7.134391632152204 5.795456417288428 0.7141688934428577 0.9374395686285235 0.28168943260998003 0.1342913893448595 0.25699001904059277 11.053282924760593 0.053008770154655604 0.040938085649195745 7.338518068202714e-08 7.134391632152204 0.2232706751856658 HYGDQVDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HYGDQVDR 8 0 Q9BQ52-3;Q9BQ52-4;E7ES68;G5E9D5;Q9BQ52-2;Q9BQ52 Q9BQ52-3;E7ES68 ELAC2 Zinc phosphodiesterase ELAC protein 2 0 ; 107.57 0.0031958999999999998 4346100.0 5383.2 2682.1 5615.2 7632.799999999999 8424.6 6430.0 5561.0 6930.5 7737.2 6444.7 False True 6294.469436953533 2948.3611626186157 5749.087663764587 7205.158961871477 6773.86010649712 6092.799480631923 5034.221821846527 6748.581718471738 7850.341912655685 7613.07309378287 0.8267974521476538 0.38727608763225474 0.7551599193838706 0.9464192544999322 0.8897668553883866 0.8003074981123639 0.6612601455196413 0.8864464632531758 1.0311659714743284 1.0 12.894263214372419 -3.300688668304806 0.16088825575123336 1.0443725637822818 7.451447588353412e-10 0.31045972580572767 0.14838558519376074 46.536896584824035 0.8107732671253538 0.5264278663213658 10.46310647229481 0.0005003931221085674 3.300688668304806 -1.044372563037137 HYGDQVDR ddPTM_PC-9_Lapatinib_30min_R1 3 HYGDQVDR 8 0 Q9BQ52-3;Q9BQ52-4;E7ES68;G5E9D5;Q9BQ52-2;Q9BQ52 Q9BQ52-3;E7ES68 ELAC2 Zinc phosphodiesterase ELAC protein 2 0 ;; 119.21 0.0029118000000000004 5553800.0 7882.4 4427.0199999999995 8217.5 5617.0 6434.3 8685.0 5524.16 4804.1 6834.3 2941.32 False True 7769.995530544874 4416.769507185297 7541.888870467316 6030.0929177627095 6055.847124320515 8313.56279572384 5810.173974877529 5027.316024229294 6064.549165630499 3449.7232429374567 2.25235330006609 1.2803257525738196 2.186230123215728 1.7479932426776517 1.7554588289708513 2.4099216691495515 1.684243507583564 1.4573099550874433 1.7579813621415339 1.0 11.752264909724671 -8.833377751846621 0.7282947348832097 1.001629551511604 1.8939497478734901 0.3981420113980825 0.3246527397311024 1.1896584176772733 1.223519235584409 0.3251197031591306 0.11640778662222329 1.4676491525964611e-09 8.833377751846621 0.8923201963618861 HYGEHVCTAK ddPTM_PC-9_Lapatinib_30min_R1 1 HYGEHVCTAK 10 0 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 0 58.37 0.032476 1369000.0 19076.0 19308.0 18642.0 16632.0 18920.0 14891.0 15899.0 15437.0 20551.0 13044.0 False True 18803.972741890037 19263.29351227998 17109.326720200996 17855.17276272554 17807.16279815119 14254.146642616426 16722.172425595527 16154.259375539155 18236.32996837605 15298.63801996252 1.2291272410886223 1.259150879126897 1.118356202550566 1.1671086497652345 1.1639704642279531 0.9317265121259041 1.0930497475510892 1.0559279430273578 1.1920231032710404 1.0 13.901115600486458 -5.699003983640282 0.9266740973071442 1.0664328121167692 1.2558618392768532 0.440026404407597 0.07304475595271283 0.7341662959225355 1.1271822956757924 0.03016652559916991 0.10592422264808124 1.9998435256424403e-06 5.699003983640282 0.18942902716008403 HYGGLTGLNK ddPTM_PC-9_Lapatinib_30min_R1 2 HYGGLTGLNK 10 0 P18669;Q8N0Y7;P15259 P18669 PGAM1;PGAM4;PGAM2 Phosphoglycerate mutase 1;Probable phosphoglycerate mutase 4;Phosphoglycerate mutase 2 0 ; 146.23 9.410799999999999e-05 18238500.0 160242.0 148616.0 158887.0 157760.0 184482.0 174205.0 176096.0 146487.0 167228.0 151194.0 False True 157956.91969521623 148271.88878294005 145823.92418155653 169362.19667193264 173631.13146556693 166754.65824168932 185213.38923565432 153293.32079708495 148393.0216510919 177327.68144665836 0.8907628995461206 0.8361463228601534 0.8223415712195029 0.955080421117885 0.9791541289496678 0.9403757883782544 1.04446969432332 0.8644635713189361 0.8368294247152256 1.0 17.43605823779464 -5.7673604445722635 24.988664359274743 0.9453992713819985 0.8483898653287965 0.3559663583574906 0.05917468772362209 159.05179719270325 671248.9531096425 0.01743847501298742 0.026657540639771552 1.7085966693152804e-06 5.7673604445722635 -0.09700940605320207 HYGIT(ph)SPISLAAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HYGITSPISLAAPK 14 0 G3XAH6;P51003;G3V457;G3V3I9;A0A0C4DGK1;P51003-2 G3XAH6 PAPOLA Poly(A) polymerase alpha 1 HYGIT(0.648)S(0.351)PISLAAPK 193.0 5.493800000000001e-07 5969500.0 40853.0 35715.0 38223.0 46577.0 51835.0 42535.0 41846.0 38434.0 39517.0 32820.0 True False 47768.60601647025 39260.549167787845 39134.38128153473 43967.441694671405 41678.30385066095 40304.389721411964 37882.04394119576 37425.14822418911 40094.861366180914 38770.00619702295 1.232102099074162 1.0126526410202783 1.0093983757098226 1.1340581549364712 1.075014113716116 1.0395765612363208 0.9770966697473633 0.965311896882361 1.0341721681040044 1.0 15.242653345239873 -6.962065665791012 2.7606241315808773 0.9917167188523361 1.0862156111337573 0.3607013739963213 0.06151928504621963 0.3305458496738204 5.117270138402802 0.02467837884488797 0.020339800404239602 1.0912753219759008e-07 6.962065665791012 0.09449889228142117 HYGIT(ph)SPISLAAPK ddPTM_PC-9_Lapatinib_30min_R1 1 HYGITSPISLAAPK 14 0 G3XAH6;P51003;G3V457;G3V3I9;A0A0C4DGK1;P51003-2 G3XAH6 PAPOLA Poly(A) polymerase alpha 1 HYGIT(0.499)S(0.499)PIS(0.001)LAAPK 206.46 2.0311000000000004e-10 6829500.0 29291.0 28036.0 35010.0 31290.0 33699.0 32039.0 30663.0 28940.0 30934.0 23654.0 True False 28873.304968688455 27971.084364526698 32131.612942508153 33591.1709803801 31716.891074783114 30668.76665655682 32250.58010478872 30284.658050664188 27449.8871705389 27742.562383026194 1.0407584047230651 1.008237234122264 1.1582063869546284 1.2108171738646707 1.1432574481363893 1.1054770728503787 1.1624946412491688 1.091631610394912 0.9894503179466089 1.0 14.759813424837455 -8.182942366949959 3.9385970388609883 0.9934719091324087 1.1200811874135568 0.43042121077800355 0.05591559448573569 0.23605596977913304 6.6570296560962126 0.04915809204737152 0.016216706183793166 6.562323458395263e-09 8.182942366949959 0.1266092782811481 HYGITS(ph)PISLAAPK ddPTM_PC-9_AZD4547_30min_R2 1 HYGITSPISLAAPK 14 0 G3XAH6;P51003;G3V457;G3V3I9;A0A0C4DGK1;P51003-2 G3XAH6 PAPOLA Poly(A) polymerase alpha 1 HYGIT(0.015)S(0.979)PIS(0.006)LAAPK 240.11 2.6805e-27 9677400.0 45300.0 36984.0 51614.0 69254.0 59365.0 48788.0 49410.0 62287.0 45474.0 50368.0 True False 59704.457701465784 48938.354738461516 50929.56463601147 53288.56026363401 51123.194464490334 45737.27864744772 53807.3942801468 52661.97536286894 47877.66280298906 48604.63165082604 1.228369718556464 1.006866075851226 1.0478335686583875 1.0963679479449027 1.0518173418483563 0.9410065891667015 1.1070425276894849 1.0834764830889105 0.985043218657442 1.0 15.568806177769252 -4.755222237775741 24.999459724706995 1.0401845502106988 1.2283700289372659 0.568167253955577 0.050295473801999266 158.7283860229823 638193.9043020845 0.012511902431725208 0.1135750018293477 1.7570242769688964e-05 4.755222237775741 0.1881854787265671 HYGITS(ph)PISLAAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 HYGITSPISLAAPK 14 0 G3XAH6;P51003;G3V457;G3V3I9;A0A0C4DGK1;P51003-2 G3XAH6 PAPOLA Poly(A) polymerase alpha 1 HYGIT(0.094)S(0.875)PIS(0.031)LAAPK 80.37100000000001 0.011676 7431700.0 49499.0 38931.0 45444.0 56113.0 47799.0 45326.0 41887.0 40192.0 47114.0 34683.0 True False 57878.203050186305 42795.81239398433 46527.55730732973 52969.170530800555 38433.129077992526 42949.02476813729 37919.16012438148 39137.002586944116 47802.953119068945 40970.75334952307 1.4126711939227754 1.044545410939643 1.1356285521625964 1.2928532233449195 0.9380625430564585 1.048284965661664 0.92551776631715 0.9552424446059082 1.1667579727241069 1.0 15.32230680015943 -6.266084174127649 24.99211946899606 1.0015321104515076 1.2026620800707168 0.47229604548390813 0.11098185666319753 372.3805786339176 2003655.792424388 0.03339944360686309 0.03916220950237888 5.418958510030292e-07 6.266084174127649 0.20112996961920926 HYGITS(ph)PISLAAPK ddPTM_PC-9_Lapatinib_30min_R1 1 HYGITSPISLAAPK 14 0 G3XAH6;P51003;G3V457;G3V3I9;A0A0C4DGK1;P51003-2 G3XAH6 PAPOLA Poly(A) polymerase alpha 1 HYGIT(0.176)S(0.823)PISLAAPK 63.461999999999996 0.025166 12360000.0 196640.0 199360.0 211370.0 205810.0 199280.0 206630.0 166240.0 185520.0 210410.0 156980.0 True False 193835.87754064015 198898.39416864212 193991.97451179507 220945.9539620339 187558.74219955422 197792.91657805585 174847.09378143284 194139.93647405718 186711.41008447297 184113.78383729834 1.0528048117892859 1.080301485435816 1.0536526406041717 1.2000511279333883 1.0187110290737396 1.0742971680645366 0.9496686784512859 1.0544562847375891 1.014108809199588 1.0 17.490238113777046 -6.744033154491544 2.1614776307984824 1.0122058125997893 1.0909944415037929 0.3294286402271126 0.0510724585009236 0.37068748953578745 3.560199879828865 0.0195090966105765 0.0181765089290956 1.802880101867527e-07 6.744033154491544 0.07878862890400362 HYNGEAYEDDEHHPR ddPTM_PC-9_AZD4547_30min_R2 2 HYNGEAYEDDEHHPR 15 0 P31689 P31689 DNAJA1 DnaJ homolog subfamily A member 1 0 ; 94.71700000000001 0.00084056 53839000.0 8832.6 7021.6 13590.6 19078.5 18617.5 13899.2 13112.4 14888.0 14412.0 12496.5 False True 11641.183070506991 9291.194885128198 13410.379764059715 14680.246584886676 16032.78148644232 13030.080826773083 14279.378197915343 12587.401692205312 15173.78889731887 12059.00133863857 0.9653521667011649 0.7704779711200487 1.1120638755624943 1.2173683518758143 1.3295281289231848 1.080527355530101 1.1841260977525894 1.0438179198034983 1.2582956474762237 1.0 13.557822815522924 -5.379469627349073 5.245654253991625 1.1654717811234088 0.8704415175771076 0.5491906394701759 0.10376508454207613 0.14617932417261642 5.6331861857442815 0.02649132634987322 0.0567849427705187 4.1737878708607905e-06 5.379469627349073 -0.29503026354630113 HYNGEAYEDDEHHPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 HYNGEAYEDDEHHPR 15 0 P31689 P31689 DNAJA1 DnaJ homolog subfamily A member 1 0 ;;; 94.09 0.0008749000000000001 54576600.0 20025.3 26664.100000000002 31065.499999999996 26366.7 35462.200000000004 26017.3 28745.800000000003 27249.7 20890.399999999998 19115.170000000002 False True 23415.187772296318 29311.13563110214 31806.219336564824 24889.45928099475 28513.636477532717 24652.906987160964 26022.789722430472 26534.42424844374 21195.882579246037 22580.599005397537 1.036960435225801 1.2980672312588242 1.4085640212184827 1.1022497354939662 1.26274933940933 1.0917738267823665 1.1524401862063152 1.1750983329583553 0.9386767186370696 1.0 14.462796137168517 -7.837322888016938 0.7308952568408978 0.976727820271811 1.2303701950038761 0.36667348334483174 0.10900724903241198 0.715521136001274 0.7478505965276822 0.10160960943198767 0.047269442591503966 1.454377382194178e-08 7.837322888016938 0.2536423747320651 HYNGEAYEDDEHHPR ddPTM_PC-9_Lapatinib_30min_R1 3 HYNGEAYEDDEHHPR 15 0 P31689 P31689 DNAJA1 DnaJ homolog subfamily A member 1 0 ;; 98.943 0.00060902 52453400.0 19221.0 14913.400000000001 21070.8 11871.699999999999 16648.6 18956.9 11956.3 12642.600000000002 25606.1 12158.5 False True 18946.9050153003 14878.868938576574 19338.440159640137 12744.784420830254 15669.362080406958 18146.15757769225 12575.33871137479 13230.02135008041 22722.071373813145 14260.080524817116 1.3286674631553872 1.0433930518612828 1.356124190602223 0.8937386011706062 1.0988270405021374 1.2725143834995962 0.8818560799491746 0.9277662441706361 1.593404142022161 1.0 13.799694508065214 -3.6097138974301455 2.44655048526859 1.1133272289251288 38.34079397331323 0.0738070963835662 0.21699545777836604 792.0397251006456 32.15224155811556 0.05448818076142453 162688.90461311155 0.00024563265505794145 3.6097138974301455 37.2274667443881 HYQGEEKS(ph)D ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HYQGEEKSD 9 1 P13984 P13984 GTF2F2 General transcription factor IIF subunit 2 1 HYQGEEKS(1)D;HYQGEEKS(1)D 81.709 0.007944 10504000.0 27418.1 40312.0 36205.0 30221.0 66151.0 69401.0 26078.0 43738.0 68353.0 85769.0 True False 32059.442797840635 44313.90894727327 37068.264508227105 28527.815347803957 53189.18641892687 65761.48938652198 23607.703051629862 42589.92384424164 69352.5333138286 101318.24075296956 0.3164232082948104 0.4373734543547575 0.36585973298337854 0.2815664300504332 0.5249714762479029 0.6490587370822914 0.23300545761734356 0.42035790917533633 0.6845019494852996 1.0 16.628534406471545 -8.524712805721819 2.4900214443007056 0.9974835283899056 0.40522668025418734 0.7326476945832268 0.11411560053330813 0.14877357504042274 2.1851123404453228 0.11365405658071276 0.030891372601249162 2.9873574732950144e-09 8.524712805721819 -0.5922568481357182 down HYQGEEKS(ph)D ddPTM_PC-9_Lapatinib_30min_R1 2 HYQGEEKSD 9 1 P13984 P13984 GTF2F2 General transcription factor IIF subunit 2 1 HYQGEEKS(1)D;HYQGEEKS(1)D 75.73899999999999 0.012047 15473800.0 45017.0 63124.0 36531.0 53667.0 70231.0 34396.0 97425.0 96686.0 53476.0 53032.0 True False 44375.049324893254 62977.84025632702 33527.562193737955 57613.85020786385 66100.15065945857 32924.9632609922 102469.18979581389 101178.38452959657 47452.96975275544 62198.51053930179 0.713442314617063 1.0125297167129557 0.5390412391395236 0.9262898694569061 1.0627288352458444 0.5293529214045677 1.6474540773941202 1.6267010841950036 0.7629277508626354 1.0 15.924592412263982 -7.257793518553092 24.99913790188288 1.3114958151931906 0.8132156575110494 0.35950255415343546 0.2984379570970402 328.88202174151013 2255107.117309782 0.11515243997039724 0.08562812320771672 5.523399819935264e-08 7.257793518553092 -0.4982801576821412 HYS(ph)PEDEPSPEAQPIAAYK ddPTM_PC-9_AZD4547_30min_R2 2 HYSPEDEPSPEAQPIAAYK 19 0 A0A096LP25;Q6ZSR9 A0A096LP25 AAK1 Uncharacterized protein FLJ45252 1 HY(0.002)S(0.998)PEDEPS(0.001)PEAQPIAAYK;HYS(0.999)PEDEPS(0.001)PEAQPIAAYK 130.89 2.2249e-05 19535000.0 53634.0 58124.0 69344.0 91790.0 75076.0 70556.0 63806.0 88956.0 66121.0 75240.0 True False 70688.49634349709 76911.44632322984 68424.4532514353 70629.2336413632 64652.99330609074 66144.12216629741 69484.61039139944 75209.89420552248 69616.02107130313 72605.87050127363 0.9735920230066946 1.0593006569886203 0.9424093779060885 0.9727757983443535 0.8904650940719265 0.9110023984236527 0.9570109126393652 1.035865195007932 0.9588208307492428 1.0 16.147798580672323 -10.623541664818065 12.746858222650681 1.0000031972637222 0.9668398910234697 0.041159367452423434 0.04806559208980242 0.0 0.0 0.050214751214099074 0.012178866071755482 2.3793500228053915e-11 10.623541664818065 -0.033163306240252544 HYS(ph)PEDEPSPEAQPIAAYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 HYSPEDEPSPEAQPIAAYK 19 0 A0A096LP25;Q6ZSR9 A0A096LP25 AAK1 Uncharacterized protein FLJ45252 1 HYS(1)PEDEPSPEAQPIAAYK;HYS(1)PEDEPSPEAQPIAAYK 175.65 6.8698e-09 12693200.0 48757.0 46001.0 59735.0 61440.0 68261.0 54725.0 53075.0 55483.0 54902.0 43163.0 True False 57010.597105354354 50567.67526998206 61159.30894624906 57997.71599116753 54885.747065688585 51855.124662143426 48047.35177027594 54026.630039097785 55704.83788562043 50988.11022187999 1.1181155147203317 0.9917542550592997 1.199481774870809 1.1374753003942395 1.0764420730018749 1.0170042473920005 0.9423246235483715 1.059592712967697 1.092506422442705 1.0 15.637873247736643 -6.609072610215725 3.924187928613556 1.0212975950316683 1.1092927706616222 0.33056255402867485 0.06012199423040331 0.2927564449050752 8.673310099395032 0.02151511529845576 0.021624426258613237 2.4599562867199266e-07 6.609072610215725 0.08799517562995396 HYS(ph)PEDEPSPEAQPIAAYK ddPTM_PC-9_Lapatinib_30min_R1 2 HYSPEDEPSPEAQPIAAYK 19 0 A0A096LP25;Q6ZSR9 A0A096LP25 AAK1 Uncharacterized protein FLJ45252 1 HY(0.002)S(0.991)PEDEPS(0.007)PEAQPIAAYK;HYS(0.997)PEDEPS(0.003)PEAQPIAAYK 93.06200000000001 0.00047662 17657400.0 81437.0 84649.0 72453.0 65182.0 68196.0 70940.0 60470.0 63403.0 76352.0 53863.0 True False 80275.69344628336 84453.00044131896 66496.19401666784 69975.70172077787 64184.84535849467 67906.06156921695 63600.84071801762 66348.93484403113 67752.43373779616 63173.14778206391 1.2707249245078016 1.3368496490418167 1.0526021949399742 1.107681098339148 1.0160146773106975 1.074919708029759 1.0067701697789253 1.0502711543347993 1.0724878546741088 1.0 15.947023839949345 -5.266363973527674 24.997131812020317 1.0499248988301872 1.3037872968568618 0.8961262390320668 0.034882468227324714 97.80687120594136 496468.15011325537 0.008686233993109105 0.01901991522779767 5.415468405766815e-06 5.266363973527674 0.25386239802667454 HYS(ph)QDCSSIK ddPTM_PC-9_AZD4547_30min_R2 2 HYSQDCSSIK 10 0 Q9P227;Q9P227-2 Q9P227 ARHGAP23 Rho GTPase-activating protein 23 1 HY(0.001)S(0.999)QDCSSIK;HY(0.012)S(0.983)QDCS(0.004)S(0.001)IK 105.2 0.0024942 8499500.0 53685.0 47731.0 85800.0 126072.0 95146.0 95431.0 65041.0 113749.0 72736.0 80591.0 True False 70755.71328263124 63159.112319422034 84662.23593927581 97008.04819298346 81936.6202395082 89463.68448398335 70829.52299888743 96171.70574198438 76580.6764665129 77769.53361999126 0.9098127504321685 0.8121318128001027 1.088629852828547 1.2473785514388993 1.0535825075135303 1.150369306843651 0.9107618330975842 1.236624437172434 0.9847130733831128 1.0 16.2469174665899 -5.269809280408836 24.370898036635825 1.0933891311584063 0.8609722787629728 0.42270307529617557 0.1037971991681596 330.3906344159885 962011.7777955829 0.025723243584055786 0.05503091821145786 5.3726768464773745e-06 5.269809280408836 -0.23241685239543353 HYS(ph)QDCSSIK ddPTM_PC-9_Lapatinib_30min_R1 1 HYSQDCSSIK 10 0 Q9P227;Q9P227-2 Q9P227 ARHGAP23 Rho GTPase-activating protein 23 1 HY(0.006)S(0.993)QDCS(0.001)SIK 61.375 0.036345 4862500.0 47155.0 40834.0 61081.0 39262.0 51847.0 51182.0 52483.0 51718.0 55807.0 51270.0 True False 46482.561052832105 40739.451381833496 56059.15595947846 42149.45845419253 48797.46139512393 48993.065171069386 55200.312938708754 54121.00708584139 49521.427986237264 60131.95118701924 0.7730093591718733 0.677500905552321 0.9322690325668332 0.7009494556912264 0.8115063694400441 0.8147592786186786 0.9179863924093805 0.9000374346329969 0.8235460018953704 1.0 15.875844152022651 -5.299719519602077 0.040970289867795315 1.548292513785801 3.1125308899762775e-07 0.47501653463548343 0.07081184418441977 255.4743713258678 1.9632430457955985 28.57027408840705 46.894394524461035 5.0151101991410444e-06 5.299719519602077 -1.548292202532712 HYSPEDEPS(ph)PEAQPIAAYK ddPTM_PC-9_AZD4547_30min_R2 1 HYSPEDEPSPEAQPIAAYK 19 0 A0A096LP25;Q6ZSR9 A0A096LP25 AAK1 Uncharacterized protein FLJ45252 1 HY(0.002)S(0.097)PEDEPS(0.9)PEAQPIAAYK 57.141999999999996 0.015361000000000001 4668300.0 2569.9 4667.6 16205.0 44535.0 32292.0 24461.0 8579.5 32692.0 17504.0 25865.0 True False 3387.074742759314 6176.310420107148 15990.111111841097 34268.143808891065 27808.8132004939 22931.449803132284 9343.05887930621 27640.20258742452 18429.225704875764 24959.474222693294 0.13570296844152938 0.24745354669737443 0.6406429466091397 1.3729513491808363 1.1141586137744028 0.9187473100808703 0.374329154370225 1.107403238578395 0.7383659423450438 1.0 14.607299923352883 -5.380914893396214 3.3661090364056 0.9363692999096932 0.1819282799973695 0.5849966603227237 0.2511820116217053 0.17756816879413245 3.6902082218447565 0.07171316733387603 0.1702587774594434 4.159921224853184e-06 5.380914893396214 -0.7544410199123237 HYSPTDY(ph)VNWLEEY(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 HYSPTDYVNWLEEYK 15 0 H0YIE9;Q4G104;O94952-1;O94952 H0YIE9 FBXO21 F-box only protein 21 2 HYSPT(0.167)DY(0.833)VNWLEEY(1)K 72.2 0.01078 6181900.0 19350.0 14125.0 28174.0 15402.0 22302.0 18875.0 14042.0 11998.0 20332.0 16038.0 True False 19074.065451644597 14092.294430337413 25857.642474785065 16534.71445956581 20990.24020741902 18067.760249774023 14769.026051966324 12555.470880852417 18041.996054548275 18810.146930708303 1.0140306464329334 0.7491857709697732 1.3746645664192791 0.8790316482096289 1.1158998536663014 0.9605326484865302 0.7851627159730108 0.667483934447908 0.9591629518371284 1.0 14.199223497702228 -7.097818861550551 4.604394855008142 0.8268932364247252 1.0237270070914677 0.17418795112499674 0.17409097804311688 0.35567238565926573 12.514168192276129 0.06596632316697554 0.051044493915591044 7.983275896532467e-08 7.097818861550551 0.19683377066674246 HYTEAIKR ddPTM_PC-9_AZD4547_30min_R2 1 HYTEAIKR 8 1 P31948-2;P31948;P31948-3 P31948-2 STIP1 Stress-induced-phosphoprotein 1 0 52.636 0.040342 8101100.0 9992.4 9419.6 22539.0 51965.0 41069.0 27653.0 20127.0 40621.0 21534.0 27293.0 False True 13169.775345168364 12464.30148968234 22240.118133279022 39985.27210124675 35367.278252541924 25923.85353853141 21918.264008834558 34343.95782771842 22672.243277467696 26337.48037734267 0.5000393035507649 0.4732533754597497 0.8444284652381371 1.5181889660046928 1.3428497238850272 0.984295124936587 0.8322080812138041 1.3039955734438242 0.8608356969853478 1.0 14.684829713717006 -5.460703858955904 4.233032405671906 1.128770355835779 0.5018018727864122 0.5937764996782712 0.20812580021397473 0.1524549224670965 5.394324640450988 0.05887327670219374 0.12551335872216798 3.46175350857078e-06 5.460703858955904 -0.6269684830493667 IAAES(ph)SENVDCPENPK ddPTM_PC-9_Lapatinib_30min_R1 1 IAAESSENVDCPENPK 16 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 IAAES(0.782)S(0.218)ENVDCPENPK 150.59 3.0910999999999996e-05 9714500.0 42196.0 49009.0 50046.0 47533.0 53060.0 42312.0 46660.0 45272.0 45978.0 47487.0 True False 41594.277302201284 48895.522671603976 45931.4110631466 51028.73538543967 49939.11511997366 40502.414394089465 49075.826490866595 47375.50239356148 40799.4734701958 55695.064677549846 0.746821599777539 0.8779148198262763 0.8246944559463115 0.9162164669504167 0.8966524306794394 0.7272172970546097 0.881152159082573 0.8506229890896976 0.7325509667042668 1.0 15.765261870836744 -11.750313722992317 2.4452332827698617 1.5995706166397712 0.8334117707342404 0.3719672300425685 0.06666026592388216 11152460.628304353 1469579.0225576882 37292979.324239045 0.016102104598856016 1.7769952912948614e-12 11.750313722992317 -0.7661588459055307 IAAESS(ph)ENVDCPENPK ddPTM_PC-9_Lapatinib_30min_R1 1 IAAESSENVDCPENPK 16 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 IAAES(0.274)S(0.726)ENVDCPENPK 230.45 3.8338e-29 8829600.0 42116.0 49417.0 55029.0 58376.0 51971.0 49086.0 51283.0 51603.0 45573.0 45199.0 True False 41515.418116871486 49302.57797267143 50504.728038082896 62669.16577662736 48914.16795891728 46986.70620505473 53938.182810353814 54000.66376601328 40440.08883503486 53011.58692611826 0.783138565059958 0.9300339950468557 0.9527111140526854 1.1821786407558177 0.9227071060349219 0.8863478520373226 1.0174791199049924 1.018657748187646 0.7628537680148271 1.0 15.694020108542947 -4.756881536961205 2.5439317958611634 0.9725703256897783 0.735628754645988 0.22795754975899585 0.10154145787547596 0.8481381562245713 6.650745596373558 0.02655880730134325 0.4521762965508712 1.7503240615571648e-05 4.756881536961205 -0.23694157104379032 IAASS(ph)SFR ddPTM_PC-9_AZD4547_30min_R2 2 IAASSSFR 8 0 Q99961-3;Q99961-2;Q99961 Q99961-3 SH3GL1 Endophilin-A2 1 IAAS(0.128)S(0.674)S(0.198)FR;IAAS(0.133)S(0.734)S(0.133)FR 74.165 0.028172000000000003 297944000.0 104083.0 104347.0 183806.0 254593.0 209976.0 150387.0 148985.0 213818.0 136195.0 154741.0 True False 137179.2289391095 138075.1271331992 181368.61234329327 195900.51727263938 180824.4568495884 140983.27711637528 162244.37637781166 180777.34114884207 143393.98965239685 149323.56468949493 0.9186710029616659 0.9246707136968912 1.2146014108384913 1.3119196402791287 1.2109572740618453 0.944146206324082 1.0865289528493671 1.210641746496961 0.9602904267023888 1.0 17.18808232897848 -5.243924516720019 23.10530100733605 1.1279089499343427 0.921670689436188 0.308997515031017 0.11622090338504262 369.25334663049387 487105.93853580754 0.031062943599876748 0.0816484176303036 5.70263379249739e-06 5.243924516720019 -0.20623826049815464 IAASS(ph)SFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IAASSSFR 8 0 Q99961-3;Q99961-2;Q99961 Q99961-3 SH3GL1 Endophilin-A2 1 IAAS(0.127)S(0.747)S(0.127)FR;IAAS(0.152)S(0.819)S(0.029)FR 82.75 0.016027 31974400.0 106516.0 98998.0 172061.0 120288.0 166437.0 148485.0 116882.0 109082.0 120953.0 95946.0 True False 124547.05501310443 108825.86718501098 176163.58678497653 113548.65333895799 133824.86462800158 140698.18520709666 105810.09080760022 106218.71308193271 122721.708804405 113340.25029188216 1.0988775363770742 0.9601696388066429 1.5542897278884342 1.001838738193529 1.1807355664326304 1.2413788115410045 0.933561471190599 0.9371667418096437 1.0827725233389112 1.0 16.790300767937055 -7.264869544149256 24.962557534570255 0.9831390741872383 1.173131988908632 0.249838944794062 0.1565206859937044 432.3127188790005 3146071.611715329 0.0631026171749563 0.04446591003888508 5.434135406336401e-08 7.264869544149256 0.18999291472139368 IAASS(ph)SFR ddPTM_PC-9_Lapatinib_30min_R1 3 IAASSSFR 8 0 Q99961-3;Q99961-2;Q99961 Q99961-3 SH3GL1 Endophilin-A2 1 IAAS(0.081)S(0.46)S(0.46)FR;IAAS(0.126)S(0.676)S(0.197)FR;IAAS(0.154)S(0.8)S(0.046)FR 75.043 0.026929 302496000.0 328844.0 267890.0 351637.0 344198.0 310003.0 273893.0 264526.0 265330.0 365845.0 255070.0 True False 324154.62425739685 267269.7171641125 322726.7632180733 369511.46913086803 291769.23302934755 262179.2348657675 278221.8619443416 277658.20043478743 324639.68358136027 299158.5096405889 1.0835547504459708 0.8934050296119345 1.0787818257478268 1.2351695078799587 0.9752997946803557 0.8763890259406341 0.930014868300418 0.9281307116029155 1.085176162868924 1.0 18.190550575844078 -6.497659030346548 24.806716423840815 0.9538314597745133 1.0659618477492359 0.23891226605378135 0.09246026388431075 1030.4158503052734 1013542.770838259 0.030203738921958073 0.03409900613198963 3.179369250834606e-07 6.497659030346548 0.11213038797472252 IAASSS(ph)FR ddPTM_PC-9_AZD4547_30min_R2 1 IAASSSFR 8 0 Q99961-3;Q99961-2;Q99961 Q99961-3 SH3GL1 Endophilin-A2 1 IAAS(0.048)S(0.259)S(0.694)FR 80.455 0.019275 315180000.0 80050.0 82628.0 138750.0 146060.0 141810.0 131140.0 101040.0 137170.0 105230.0 111970.0 True False 105504.23485656347 109335.88512139289 136910.08434236038 112388.12360450493 122122.12931878003 122939.79506899812 110032.36425958353 115973.52835302301 110792.24296869706 108049.96438101579 0.9764393302761737 1.011901167647243 1.267099763768319 1.0401495664375373 1.1302375712789843 1.1378050494813348 1.01834706646989 1.0733324070711066 1.0253797269012621 1.0 16.721339071045705 -8.013621480958612 1.1078223651751704 1.0063001926641229 1.0939975420347048 0.12306888839156749 0.07813986570525586 1.0769476116012953 2.4304243990811556 0.0733411382199717 0.026010889054844537 9.691221482988478e-09 8.013621480958612 0.08769734937058193 IAASSS(ph)FR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IAASSSFR 8 0 Q99961-3;Q99961-2;Q99961 Q99961-3 SH3GL1 Endophilin-A2 1 IAAS(0.039)S(0.232)S(0.729)FR;IAAS(0.039)S(0.232)S(0.729)FR 98.58200000000001 0.0054621 235210000.0 172468.0 177069.0 216295.0 215831.0 269773.0 208108.0 211780.0 209669.0 180863.0 143461.0 True False 201663.4260017282 194647.24011174665 221452.2931033558 203738.68880354275 216912.91723168397 197194.45012680377 191718.66524557772 204165.410912669 183507.77921582016 169469.34366334873 1.1899699476167978 1.1485690326293696 1.3067395454323074 1.2022156007653524 1.2799537222648483 1.1635995387964153 1.1312881793324658 1.2047335907445544 1.0828376109153925 1.0 17.370664793551057 -8.48972995312231 0.6841610162797724 0.9977809544117038 1.220172506130829 0.6373818125882951 0.051066996618348334 0.5029945579326079 0.5426062368432262 0.051482150892902354 0.020820306533163458 3.237949319500703e-09 8.48972995312231 0.22239155171912528 IAAT(ph)T(ph)AY(ph)S(ph)KPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IAATTAYSKPK 11 1 O43318-3;O43318 O43318-3 MAP3K7 Mitogen-activated protein kinase kinase kinase 7 4 IAAT(1)T(1)AY(1)S(1)KPK 69.26100000000001 0.027955 5066900.0 0.0 1425.2 0.0 2548.3 10313.0 7513.5 10308.0 14721.0 11241.0 11573.0 True False 0.0 1566.684437181332 0.0 2405.5270127000704 8292.241682489943 7119.478833239183 9331.551616542702 14334.58934818879 11405.378359117327 13671.093288182414 0.0 0.11459832832357363 0.0 0.1759571792827615 0.6065529294323472 0.5207687990391677 0.6825753741735561 1.048532772472551 0.8342696607137031 1.0 13.738841000574558 -6.697168725146709 0.7358387124574021 0.978351131546391 2.0883236298755218e-19 0.9216779482562971 0.10698053514315546 0.1796472562925605 0.21515962421796617 0.07628676067946086 0.08125622739952668 2.0083124236012809e-07 6.697168725146709 -0.978351131546391 down IAAYGHEVGK ddPTM_PC-9_Lapatinib_30min_R1 2 IAAYGHEVGK 10 0 A0A087WYM2;A0A087X297;Q16719-2;Q16719;B8ZZA3 A0A087WYM2 KYNU Kynureninase 0 ; 132.88 0.00011074 15078300.0 225270.0 218200.0 214500.0 223160.0 226230.0 187825.0 215390.0 200540.0 196062.0 214670.0 False True 222057.6084905419 217694.77130616803 196864.63799394498 239571.9308399371 212923.59618529273 179792.16259146007 226541.84028863575 209857.82050726295 173979.43293561094 251775.4234702048 0.8819669744963026 0.8646386859594741 0.7819056970715095 0.9515302468284325 0.8456885634450743 0.7140973495879622 0.8997774173754683 0.8335119354177061 0.6910103875019387 1.0 17.94177793871652 -6.527377422265655 24.95983248315675 0.8171259285573587 0.8677430082903344 0.04002865222051366 0.09036759207921023 382.08875840266194 2119905.463444066 0.02854731059262323 0.02865557328442857 2.9690846364760525e-07 6.527377422265655 0.05061707973297569 IACDEEFS(ph)DSEDEGEGGRR ddPTM_PC-9_AZD4547_30min_R2 1 IACDEEFSDSEDEGEGGRR 19 1 Q92769-3;Q92769 Q92769-3 HDAC2 Histone deacetylase 2 1 IACDEEFS(0.998)DS(0.002)EDEGEGGRR 69.398 0.041164 0.0 5901.9 6133.0 3111.3 10679.0 9405.9 8718.3 8416.1 10687.0 7464.6 8371.0 True False 7778.581432853882 8115.372312648295 3070.0421291126927 8217.121538905301 8100.053142652227 8173.143322785176 9165.116595853951 9035.569712829 7859.163516717072 8077.933837934095 0.9629419587872272 1.0046346597366753 0.38005289356242683 1.017230606707569 1.00273823791602 1.0117863660140387 1.1345867371201321 1.1185496061378755 0.9729175398553433 1.0 12.979770614402607 -5.963733430798338 24.99999974969402 1.0457563437011512 0.7870671213522588 0.3370068185016054 0.1635608519433958 196.83996177012443 135688.5037888946 0.046504986508213525 0.06897782153751886 1.0870926744817147e-06 5.963733430798338 -0.25868922234889247 IACDEEFS(ph)DSEDEGEGGRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IACDEEFSDSEDEGEGGRR 19 1 Q92769-3;Q92769 Q92769-3 HDAC2 Histone deacetylase 2 1 IACDEEFS(0.997)DS(0.003)EDEGEGGRR 118.84 0.00026462 0.0 11284.0 8749.7 10782.0 13146.0 15009.0 15769.0 12439.0 12535.0 11605.0 8880.5 True False 13194.158330841074 9618.312391247193 11039.083770962703 12409.472239907038 12068.094193008013 14942.045880262023 11260.687869438754 12205.969531930332 11774.70117049699 10490.464352000687 1.2577287227828722 0.9168624065161461 1.0522969623224911 1.182928784038084 1.1503870360806716 1.4243455178809463 1.0734212987713145 1.1635299565745603 1.1224194444978386 1.0 13.356790918618271 -4.462901199187045 23.278263373196825 1.1317668954690112 4.39399933053991 0.08838913737194176 0.12764360489418727 1645.1066929084268 649870.0109485225 0.03177896237411551 4927.223414889358 3.4442827834723365e-05 4.462901199187045 3.262232435070899 IACEEEFS(ph)DSEEEGEGGRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IACEEEFSDSEEEGEGGRK 19 1 Q13547 Q13547 HDAC1 Histone deacetylase 1 1 IACEEEFS(0.994)DS(0.006)EEEGEGGRK 67.11 0.0043058 3008200.0 13082.0 10714.0 11808.0 18636.0 14337.0 16044.0 16076.0 11665.0 15327.0 11687.0 True False 15296.524218722347 11777.615113640748 12089.547502089372 17591.885338727196 11527.76776901565 15202.6243961522 14553.164899839014 11358.806110089146 15551.12837916478 13805.760585758911 1.1079812751860412 0.8530942602169806 0.8756886248310094 1.2742423881284595 0.8349969346061901 1.1011797793910898 1.0541371342373613 0.8227584448919187 1.1264231537671507 1.0 13.752982750494338 IACEEEFS(ph)DSEEEGEGGRK ddPTM_PC-9_Lapatinib_30min_R1 2 IACEEEFSDSEEEGEGGRK 19 1 Q13547 Q13547 HDAC1 Histone deacetylase 1 1 IACEEEFS(0.942)DS(0.058)EEEGEGGRK;IACEEEFS(0.969)DS(0.031)EEEGEGGRK 74.444 0.0019933 18986600.0 36184.0 38902.0 44441.0 39479.0 41338.0 41356.0 35597.0 31454.0 45644.0 35380.0 True False 35668.00952466706 38811.92480913176 40787.23252722094 42382.41735808329 38906.58011363498 39587.30028554461 37440.0384825413 32915.467668472396 40503.0920673717 41495.38585911334 0.8595656790797993 0.9353310977974137 0.9829341668421461 1.0213766297289446 0.9376122021309075 0.9540169217838549 0.9022699200739835 0.7932319940397278 0.9760866474380859 1.0 15.340663302315814 -7.26641425891274 11.481779166845127 0.9006557695915811 0.9522655257090168 0.02258023469044257 0.06474277920534494 0.668053908796393 1468.5413485730548 0.026188811108254204 0.018611485774752082 5.4148414045944664e-08 7.26641425891274 0.05160975611743568 IACKS(ph)PPPESVDTPTSTK ddPTM_PC-9_AZD4547_30min_R2 4 IACKSPPPESVDTPTSTK 18 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IACKS(1)PPPESVDTPTSTK;IACKS(0.984)PPPES(0.007)VDT(0.003)PT(0.003)S(0.001)T(0.002)K;IACKS(0.999)PPPES(0.001)VDTPTSTK;IACKS(0.995)PPPES(0.005)VDTPTSTK 127.01 2.047e-05 161759000.0 184524.0 293385.0 270498.0 370105.0 270977.0 209286.0 156392.0 187530.0 139776.0 214325.0 True False 243198.7936623675 388215.96379362734 266911.01977974677 284783.010315249 233356.520953494 196199.31333544647 170310.58502855166 158551.54751069727 147164.27400164056 206821.54698545288 1.1758871220486193 1.877057634719912 1.2905377784381449 1.3769503925781952 1.128298885463358 0.9486405850607358 0.8234663530513614 0.7666103934608383 0.7115519448850829 1.0 17.658026970097993 -6.471034128998875 1.1543368015773579 0.7973147114469423 1.5051438326261062 0.6956771822688566 0.18244889997065833 0.24057372759610343 0.6733833299113449 0.07879206376108121 0.09442471006295249 3.380382704503525e-07 6.471034128998875 0.7078291211791639 IACKS(ph)PPPESVDTPTSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IACKSPPPESVDTPTSTK 18 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IACKS(1)PPPESVDTPTSTK;IACKS(0.997)PPPES(0.001)VDT(0.002)PT(0.001)STK;IACKS(0.987)PPPES(0.01)VDT(0.003)PTSTK;IACKS(1)PPPESVDTPTSTK 95.9 0.0004093999999999999 97784000.0 131041.0 128059.0 104370.0 194174.0 212608.0 169656.0 238413.0 233429.0 176828.0 117654.0 True False 153223.6531222744 140771.85120755257 106858.57662542902 183295.0603006021 170948.98861929847 160758.94069768116 215828.7946793553 227301.7360884694 179413.77497429037 138983.73885144823 1.1024574125613817 1.012865622776313 0.7688566843035072 1.3188237833817071 1.229992731754152 1.1566744572147911 1.552906810990618 1.6354556149293065 1.2908976003736343 1.0 17.08455657140913 -6.241068899697701 1.2280266962808473 1.387755973668612 0.9784984677429769 0.32378533508229235 0.20297653331588775 0.480771111025232 1.4835728230547136 0.08303802289011981 0.12287033904401846 5.74025387338222e-07 6.241068899697701 -0.40925750592563515 IACKS(ph)PPPESVDTPTSTK ddPTM_PC-9_Lapatinib_30min_R1 4 IACKSPPPESVDTPTSTK 18 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IACKS(1)PPPESVDTPTSTK;IACKS(0.999)PPPES(0.001)VDTPTSTK;IACKS(0.974)PPPES(0.024)VDTPT(0.001)STK;IACKS(0.99)PPPES(0.01)VDTPTSTK 126.09 2.073e-05 105684000.0 194170.0 257156.0 174674.0 77813.0 100858.0 163739.0 297990.0 228589.0 124412.0 91617.0 True False 191401.1001935833 256560.57108161796 160312.97798113845 83535.62759655874 94925.73073445729 156736.2646642516 313418.46412373224 239210.07944517175 110399.41044355987 107452.87637802114 1.7812561808046048 2.3876566149707643 1.491937520752395 0.7774163932352904 0.8834173075135454 1.4586511775901707 2.9167992024812857 2.2261859105904844 1.02742163974441 1.0 16.713344576846666 IACKS(ph)PQPDPVDTPASTK ddPTM_PC-9_AZD4547_30min_R2 4 IACKSPQPDPVDTPASTK 18 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IACKS(0.999)PQPDPVDTPASTK;IACKS(1)PQPDPVDTPASTK;IACKS(0.999)PQPDPVDTPASTK;IACKS(1)PQPDPVDTPASTK 116.45 5.6747e-05 46259200.0 235577.0 358555.0 327949.0 462206.0 333060.0 242767.0 183759.0 227466.0 181232.0 273673.0 True False 310485.58569400053 474450.89182481787 323600.1819819303 355651.54771151504 286820.36803408 227586.7411126699 200113.19501164774 192316.35634868214 190811.55352753896 264091.7915695786 1.1756729879739518 1.7965378212060685 1.225332222780099 1.3466967132820324 1.086063168905851 0.8617713551793944 0.7577410635230788 0.7282178488232709 0.7225198193154256 1.0 18.010679935177336 -6.439397235007736 1.322044712955054 0.7720663136108357 1.448503936798862 0.7119456348150056 0.17168696898284985 0.20956193759573594 0.7523848121117862 0.06795915971169086 0.08194274939854622 3.6358232708691437e-07 6.439397235007736 0.6764376231880262 IACKS(ph)PQPDPVDTPASTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IACKSPQPDPVDTPASTK 18 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IACKS(0.996)PQPDPVDT(0.003)PAS(0.001)TK;IACKS(1)PQPDPVDTPASTK;IACKS(1)PQPDPVDTPASTK;IACKS(0.999)PQPDPVDTPASTK 87.319 0.00078059 33802300.0 167582.0 167851.0 131351.0 240336.0 272811.0 225631.0 290635.0 278120.0 239558.0 151608.0 True False 195950.32270462674 184514.137991386 134482.9059914413 226870.7530998255 219355.64294014982 213798.5131593255 263103.94878481625 270819.64469249785 243061.08255078987 179093.33027173238 1.0941240659678269 1.0302680602981071 0.7509096278872857 1.2667738812807936 1.2248119045378674 1.1937826653563037 1.469088482444418 1.5121704659888349 1.3571755139178066 1.0 17.45035208444036 -5.891421426816311 7.3951218565308885 1.315358674969165 0.9668813421198227 0.4718897915211502 0.15927413389043407 0.19267881592513092 11.929896356951595 0.0464023512043529 0.06918160303878142 1.28404005983731e-06 5.891421426816311 -0.34847733284934235 IACKS(ph)PQPDPVDTPASTK ddPTM_PC-9_Lapatinib_30min_R1 2 IACKSPQPDPVDTPASTK 18 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IACKS(1)PQPDPVDTPASTK;IACKS(1)PQPDPVDTPASTK 107.56 0.00013816 15630000.0 45958.0 62060.0 41543.0 20263.0 25149.0 40759.0 64706.0 58956.0 26470.0 22203.0 True False 45302.63049233502 61916.30388295501 38127.494900617436 21753.20861538646 23669.785264836366 39015.832583869655 68056.16007111037 61695.31098945954 23488.669858542842 26040.758966362147 1.7396816487128572 2.377668944401148 1.4641468380344902 0.8353523276140268 0.9089514363007446 1.4982601941159976 2.613447640255844 2.369182521490781 0.9019963622751573 1.0 14.668483876480428 -7.036515962440268 24.96113010884278 1.8667692678005128 1.453088779015467 0.015804514785228263 0.6408442399906725 1658.6975952596192 1133826.9488441092 0.25960709454639497 0.20115875357001511 9.193566833411618e-08 7.036515962440268 -0.4136804887850458 IACRS(ph)PQPDPVGTPTIFKPQSK ddPTM_PC-9_AZD4547_30min_R2 1 IACRSPQPDPVGTPTIFKPQSK 22 2 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IACRS(1)PQPDPVGTPTIFKPQSK 56.748000000000005 0.0037146 9928100.0 36193.0 55647.0 59197.0 98760.0 65385.0 56069.0 32183.0 39259.0 37381.0 53600.0 True False 47701.62113883337 73633.80451360495 58412.00910136734 75992.40782678983 56307.42137725423 52562.99656644551 35047.22465326787 33192.42363207203 39356.88334517598 51723.480314570275 0.9222430673404635 1.4236049868605347 1.129313200622212 1.4692052306732173 1.0886239873033579 1.016230853894005 0.6775882914320293 0.6417283491018657 0.7609094188135929 1.0 15.658531732494263 -6.934208064862743 2.1865667560766147 0.7423080712932056 1.2381062549879953 0.5823833354613039 0.1731948115938931 0.19541682379314865 1.8955981013308285 0.06897578088803367 0.05665428674552303 1.1635684452800213e-07 6.934208064862743 0.4957981836947897 IADGSVKR ddPTM_PC-9_AZD4547_30min_R2 1 IADGSVKR 8 1 A0A0A0MSS8;P42330;S4R3Z2;S4R3D5;A6NHU4;P17516;B4DK69;P52895;H0Y804;S4R3P0;P52895-2;Q04828 A0A0A0MSS8;B4DK69;Q04828 AKR1C3;AKR1C1;AKR1C4;AKR1C2 Aldo-keto reductase family 1 member C3;Aldo-keto reductase family 1 member C4;Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 80.165 0.012454999999999999 2655500.0 19842.0 11034.0 28376.0 57181.0 44567.0 21893.0 19302.0 32688.0 20272.0 26124.0 False True 26151.343260761245 14600.524718369676 27999.715699450957 43998.803887643415 38379.64133241706 20524.02724908937 21019.840607071328 27636.820695513674 21343.536533891755 25209.40671152675 1.0373644869953962 0.5791697077779198 1.1106852303131896 1.7453327795899853 1.5224333429024473 0.8141416211792467 0.8338094127959075 1.0962900083990081 0.8466496962077507 1.0 14.621674545171128 -6.803821617522931 24.999986887623216 0.9189231456242097 1.19000964147157 0.18219636287177066 0.29716793015889564 310.56390469414765 183189.9955737242 0.12018088156291126 0.10599038924690668 1.571007948943759e-07 6.803821617522931 0.2710864958473602 IADGSVKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IADGSVKR 8 1 A0A0A0MSS8;P42330;S4R3Z2;S4R3D5;A6NHU4;P17516;B4DK69;P52895;H0Y804;S4R3P0;P52895-2;Q04828 A0A0A0MSS8;B4DK69;Q04828 AKR1C3;AKR1C1;AKR1C4;AKR1C2 Aldo-keto reductase family 1 member C3;Aldo-keto reductase family 1 member C4;Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 ; 79.71300000000001 0.012861000000000001 8471000.0 46590.0 23451.0 43777.0 75499.0 82766.0 96942.0 68315.0 86354.0 92123.0 72592.0 False True 54476.76680555526 25779.060297740238 44820.80970519703 71269.03580106051 66548.59644070239 91858.19086336232 61843.70864223082 84087.29899962623 93470.12459540673 85752.35496204425 0.635280125305804 0.30062218476857666 0.5226773040231448 0.831102957261123 0.7760556135182312 1.0712031279376601 0.7211896241170765 0.9805829710081431 1.090000672713636 1.0 16.387888671189543 -5.865372795036152 1.8437202328683016 0.9395312542573513 0.44682232564192703 0.7001302210534969 0.1331165946578483 0.1857669100856937 1.2878025910473445 0.04163207228196529 0.07661180829100643 1.363412291535416e-06 5.865372795036152 -0.49270892861542426 IADGSVKR ddPTM_PC-9_Lapatinib_30min_R1 1 IADGSVKR 8 1 A0A0A0MSS8;P42330;S4R3Z2;S4R3D5;A6NHU4;P17516;B4DK69;P52895;H0Y804;S4R3P0;P52895-2;Q04828 A0A0A0MSS8;B4DK69;Q04828 AKR1C3;AKR1C1;AKR1C4;AKR1C2 Aldo-keto reductase family 1 member C3;Aldo-keto reductase family 1 member C4;Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 90.37 0.006027899999999999 5854700.0 85799.0 37780.0 45821.0 37292.0 34889.0 36294.0 23369.0 25733.0 51020.0 27445.0 False True 84575.49052639036 37692.522731196295 42053.77425417499 40034.57808246519 32836.89761441313 34741.7902254463 24578.932474604822 26928.64912293509 45273.590335582005 32188.831681836215 2.6274793494327207 1.1709813858346947 1.306470973219741 1.2437412602662505 1.0201332542598187 1.0793119355447338 0.7635857280422648 0.8365836135062528 1.4064999557324527 1.0 14.974272593599913 -2.913692532409863 1.3034756601944906 1.046533079543711 199.99999995630725 0.8440624279590009 0.1967799018440983 68.87255674779469 1.2200932212661257 0.05849190213092863 39950.0168701011 0.0012198529129085374 2.913692532409863 198.95346687676354 up IADGYEQAAR ddPTM_PC-9_Lapatinib_30min_R1 2 IADGYEQAAR 10 0 E7ENZ3;B7ZAR1;E9PCA1;P48643-2;P48643 E7ENZ3 CCT5 T-complex protein 1 subunit epsilon 0 ; 148.69 0.00070397 13326900.0 61490.0 63387.0 81236.0 59182.0 59712.0 63771.0 57927.0 60193.0 68529.0 60089.0 False True 60613.14132411507 63240.23129598567 74557.0896600282 63534.44170536449 56199.85755830888 61043.662987461685 60926.17662101218 62989.786525350035 60810.54237763818 70475.30358644036 0.8600621528330273 0.8973388985606763 1.0579179636818645 0.9015135582557275 0.79744044648744 0.8661709830393217 0.8645039257799598 0.8937852456086395 0.8628631489760378 1.0 16.10483016705545 -4.768615423291862 7.357932317798703 0.9002395770450993 0.8594621378893211 0.031800449060386704 0.07018884518435564 0.4899620505565144 175.38319161231556 0.018416021895862427 0.09854671454567732 1.7036664723785954e-05 4.768615423291862 -0.04077743915577814 IADMGHLK ddPTM_PC-9_Lapatinib_30min_R1 1 IADMGHLK 8 0 P12004 P12004 PCNA Proliferating cell nuclear antigen 0 111.95 0.0031371 6713500.0 127600.0 138110.0 130760.0 132630.0 145160.0 136010.0 133970.0 112080.0 139460.0 117450.0 False True 125780.40060102587 137790.21478045336 120009.41754819686 142384.0526407102 136621.97419554048 130193.16935479546 140906.31107975545 117287.64596815618 123752.54622109496 137751.07600771234 0.9130992239507715 1.0002841268023113 0.8712049373863172 1.033632961478562 0.9918033176589586 0.9451335926225816 1.022905338843716 0.8514463143764448 0.8983780730262053 1.0 17.071704062524915 -10.080201031078222 5.021343967839701 1.00000000033011 0.9500021839318711 0.06213845878181523 0.06046274186460919 81857240.15886404 244232667.51582497 4.832659739685329 0.015125809339636647 8.313788440990685e-11 10.080201031078222 -0.04999781639823886 IADPEHDHTGFLT(ph)EYVATR ddPTM_PC-9_AZD4547_30min_R2 2 IADPEHDHTGFLTEYVATR 19 0 B3KR49;E9PJF0;E9PQW4;P27361-2;P27361-3;P27361 B3KR49 MAPK3 Mitogen-activated protein kinase;Mitogen-activated protein kinase 3 1 IADPEHDHTGFLT(0.468)EY(0.468)VAT(0.064)R;IADPEHDHT(0.001)GFLT(0.359)EY(0.28)VAT(0.359)R 156.17 3.4316e-05 5475300.0 35820.0 32750.0 45676.0 76345.0 61472.0 52348.0 36020.0 48665.0 35662.0 46983.0 True False 47210.01489771532 43335.7970388442 45070.30639583179 58744.83976849199 52937.67388395768 49074.671284672324 39225.71022001394 41144.94246044945 37547.020514584045 45338.13947051222 1.0412869925644073 0.955835363888932 0.9940925437653957 1.295704686044725 1.1676190179437815 1.082414758474823 0.8651812950005638 0.9075128124128249 0.8281553004398097 1.0 15.46843756834011 -7.254087133499146 22.091352769314422 0.8925050887871661 1.0920051279677891 0.4751547370618303 0.0972996554368601 109.18446571720531 328069.02747481654 0.04168715849060195 0.031503132014950246 5.570739706892303e-08 7.254087133499146 0.1995000391806231 IADPEHDHTGFLT(ph)EYVATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IADPEHDHTGFLTEYVATR 19 0 B3KR49;E9PJF0;E9PQW4;P27361-2;P27361-3;P27361 B3KR49 MAPK3 Mitogen-activated protein kinase;Mitogen-activated protein kinase 3 1 IADPEHDHT(0.001)GFLT(0.539)EY(0.431)VAT(0.029)R 66.26100000000001 0.020963 7774200.0 7227.5 6156.5 6776.4 10256.0 24809.0 26249.0 25473.0 29389.0 27633.0 26032.0 True False 8450.97300036812 6767.676633108942 6937.975075640107 9681.38957040063 19947.85454289664 24872.45623127642 23060.013031450566 28617.56989021944 28037.080348500054 30751.39553080138 0.2748159182533167 0.2200770571966487 0.2256149666017874 0.3148276493892287 0.6486812776648253 0.808823658307264 0.7498850908523182 0.9306104453554102 0.9117335933719627 1.0 14.908364262511325 -6.440385736786379 1.3409113696460673 0.8968560333619154 0.21930373281186002 0.9602593468711396 0.05999669834966655 0.07816856036874666 0.28821683567702505 0.02554535343885262 0.030703701079160088 3.627557149994428e-07 6.440385736786379 -0.6775523005500554 down IADPEHDHTGFLTEY(ph)VATR ddPTM_PC-9_AZD4547_30min_R2 3 IADPEHDHTGFLTEYVATR 19 0 B3KR49;E9PJF0;E9PQW4;P27361-2;P27361-3;P27361 B3KR49 MAPK3 Mitogen-activated protein kinase;Mitogen-activated protein kinase 3 1 IADPEHDHTGFLTEY(0.999)VATR;IADPEHDHT(0.048)GFLT(0.133)EY(0.466)VAT(0.353)R;IADPEHDHTGFLTEY(0.999)VATR 140.68 1.6547999999999998e-05 76689900.0 183385.8 187882.1 243864.5 337480.0 324940.0 262021.0 160655.0 243808.0 232548.0 268230.0 True False 241698.66973839924 248611.31459028515 240630.6973917663 259679.20001402366 279827.6898726776 245636.78544894003 174952.98377002575 206133.07575048305 244840.01252384877 258839.34934285824 0.9337786945919321 0.9604850082549657 0.9296526899896785 1.0032446792703569 1.0810863594855442 0.9489932117066555 0.675913396530306 0.7963745708440932 0.9459149590100925 1.0 17.98169743020039 -7.021716111827124 24.715755370404988 0.8339921228734037 0.9824102200120846 0.29670193685464874 0.09071353416294167 730.3515605865286 831232.9197365602 0.03452590989630228 0.027004921518697152 9.512263849747217e-08 7.021716111827124 0.14841809713868082 IADPEHDHTGFLTEY(ph)VATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IADPEHDHTGFLTEYVATR 19 0 B3KR49;E9PJF0;E9PQW4;P27361-2;P27361-3;P27361 B3KR49 MAPK3 Mitogen-activated protein kinase;Mitogen-activated protein kinase 3 1 IADPEHDHTGFLT(0.001)EY(0.999)VATR;IADPEHDHTGFLT(0.3)EY(0.666)VAT(0.034)R;IADPEHDHTGFLTEY(0.999)VATR 156.11 6.5167e-06 35375700.0 24923.7 27310.1 28169.5 40944.0 97988.0 115067.0 120809.0 104688.0 116159.0 108601.0 True False 29142.79014448633 30021.26624183685 28841.167713423667 38650.04042223902 78787.95481274363 109032.68395612354 109365.09693858252 101940.05092610474 117857.6056237622 128289.50161495697 0.22716426346369595 0.23401187052656489 0.22481315579498007 0.30127204436604427 0.6141418730366158 0.8498956078523863 0.852486723869476 0.7946094547320293 0.9186847258748837 1.0 16.969043588841444 -6.4274666393757 1.8141844017796163 0.87748146431181 0.22394607085469626 0.9730275808064804 0.050050833142163534 0.05086349347042463 0.3335213098597838 0.018106370114394 0.021139982618545317 3.737088309761376e-07 6.4274666393757 -0.6535353934571138 down IADPEHDHTGFLTEY(ph)VATR ddPTM_PC-9_Lapatinib_30min_R1 2 IADPEHDHTGFLTEYVATR 19 0 B3KR49;E9PJF0;E9PQW4;P27361-2;P27361-3;P27361 B3KR49 MAPK3 Mitogen-activated protein kinase;Mitogen-activated protein kinase 3 1 IADPEHDHTGFLT(0.001)EY(0.999)VATR;IADPEHDHTGFLTEY(0.999)VATR 140.8 7.1774e-05 34741000.0 8998.4 9421.0 10620.8 16619.5 70184.0 113992.0 98557.0 102465.0 147633.0 99280.0 True False 8870.081165895539 9399.18625332452 9747.598821473593 17841.75347102677 66055.91510705299 109116.82788833058 103659.7992168954 107225.89796687328 131005.01689558967 116440.41571771564 0.0761769967173521 0.0807209953295838 0.08371319151852324 0.15322646661001454 0.5672937072570329 0.9371044170166868 0.8902389997318108 0.9208649531690014 1.125082009438911 1.0 16.829232369755715 -6.476638827550332 1.7719848612702345 0.9819633034426639 0.0717391375522208 0.9802611948842156 0.05869039573082208 0.04528147069179426 0.2856107255441373 0.022674606045116178 0.02559083336907753 3.3370381560275976e-07 6.476638827550332 -0.9102241658904431 down IAEFTTNLTEEEEK ddPTM_PC-9_AZD4547_30min_R2 1 IAEFTTNLTEEEEK 14 0 P35579 P35579 MYH9 Myosin-9 0 117.92 0.0023963 0.0 3380.0 2731.4 2533.0 6976.9 5092.3 4604.1 3375.3 4257.5 4404.9 4384.1 False True 4454.769691632547 3614.2716345618046 2499.4107649672014 5368.483497030469 4385.32204449632 4316.204899170161 3675.695161177487 3599.6012026171497 4637.734021218419 4230.613993416187 1.052984200062969 0.8543137332279537 0.5907914947704664 1.2689608424179255 1.036568699323761 1.0202313200606752 0.8688325540684444 0.8508460493486195 1.096231901193492 1.0 12.046651343036778 -5.758126369428594 24.999999741079655 1.0083955127721056 0.8348582984994666 0.2418325706761424 0.1511422159850714 140.37727889887728 1059266.5651889031 0.04319206904883139 0.07103206019042653 1.7453142338406973e-06 5.758126369428594 -0.17353721427263902 IAEFTTNLTEEEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IAEFTTNLTEEEEK 14 0 P35579 P35579 MYH9 Myosin-9 0 151.54 3.5172e-08 0.0 8775.6 6876.0 5580.8 6630.8 8100.1 8827.5 8559.9 6254.6 9011.4 7155.9 False True 10261.135753999373 7558.603838099103 5713.8674373018575 6259.297773343648 6512.943552054382 8364.570360074387 7749.044303690713 6090.423377296487 9143.174677106123 8453.20802392677 1.2138747473095741 0.8941698603304812 0.6759407104532125 0.7404641830210178 0.7704700432805536 0.9895143165054622 0.9166986405347028 0.7204866318275345 1.081621870800577 1.0 13.045283238114836 -8.282310125898373 24.696762683153484 1.0408109848292004 0.8584038318376253 0.178412138096825 0.1501712916685609 1408.9612173749758 1667232.8938624961 0.1490051862560503 0.03864946934001716 5.220232836008801e-09 8.282310125898373 -0.18240715299157517 IAEFTTNLTEEEEK ddPTM_PC-9_Lapatinib_30min_R1 2 IAEFTTNLTEEEEK 14 0 P35579 P35579 MYH9 Myosin-9 0 ; 192.65 2.2408000000000002e-06 6000300.0 21010.0 19955.6 19288.0 19891.6 20579.5 21069.7 22128.6 18192.5 18348.1 18841.7 False True 20710.39354723787 19909.39403426841 17702.21509383312 21354.494620432386 19369.05427085372 20168.598046869614 23274.310631928623 19037.789964986478 16281.543763941441 22098.46274001288 0.9371870700190522 0.9009402268610838 0.8010609290835586 0.9663339423953043 0.8764887629845347 0.9126697311098961 1.0532094881779572 0.8614983851575995 0.7367726866566625 1.0 14.431658392854041 -4.763377299035043 8.482277072516995 0.8999195805404293 0.937523331866807 0.015049243661421796 0.08746592718310083 0.5483501921616004 442.10972361304886 0.021840433744911802 0.12159798806579283 1.7243391987538925e-05 4.763377299035043 0.03760375132637772 IAEPS(ph)VCGR ddPTM_PC-9_AZD4547_30min_R2 4 IAEPSVCGR 9 0 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IU45 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 IAEPS(1)VCGR;IAEPS(1)VCGR;IAEPS(1)VCGR;IAEPS(1)VCGR 93.556 0.0061653 24673000.0 63663.0 53183.2 94727.0 95762.0 98031.0 84345.0 85245.0 89343.0 74775.0 80927.0 True False 83906.50972733811 70373.62934584005 93470.8580864778 73685.55040815141 84421.08778823297 79070.89381649123 92831.63985855316 75537.09224789748 78727.45384381188 78093.77036226161 1.0744328176000768 0.9011426778268055 1.196905433722625 0.9435522201878417 1.0810220507553954 1.0125121818257325 1.188720168432456 0.9672614332423163 1.0081143922058153 1.0 16.252919846918843 -4.44865632273188 23.23131454104263 1.0371541394556578 3.0502475422486315 0.016008356833262183 0.09240861498982943 3140.03403819879 1429668.5963680302 0.020907764061217856 150888.79511912767 3.559128574279642e-05 4.44865632273188 2.0130934027929737 IAEPS(ph)VCGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IAEPSVCGR 9 0 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IU45 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 IAEPS(1)VCGR;IAEPS(1)VCGR;IAEPS(1)VCGR 88.134 0.010353 14180500.0 47143.5 59350.0 57488.8 59137.0 72375.0 55042.0 65635.0 53674.6 49128.8 42313.2 True False 55123.96342343194 65241.875769514474 58859.55101948814 55823.745614740794 58193.63829828464 52155.50062409679 59417.57764375048 52265.698622939635 49847.21575744181 49984.24820889307 1.1028266983842407 1.30524871549247 1.177561994600851 1.1168267527290483 1.1642395431273282 1.043438733061057 1.1887260441616296 1.0456433875830637 0.9972584872962662 1.0 15.609185902211482 -7.288418063539889 0.43471264669119203 0.986083187580219 1.2136901900472492 0.49928988716195455 0.06528924828581449 0.9077453025209951 0.3945556132129485 0.06778118897639321 0.07098981906101187 5.1473291028363795e-08 7.288418063539889 0.22760700246703025 IAEPS(ph)VCGR ddPTM_PC-9_Lapatinib_30min_R1 4 IAEPSVCGR 9 0 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IU45 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 IAEPS(1)VCGR;IAEPS(1)VCGR;IAEPS(1)VCGR;IAEPS(1)VCGR 95.48299999999999 0.005411600000000001 23458100.0 76821.0 92847.0 95599.0 70863.0 91805.0 90047.0 91230.0 82502.0 95294.0 73042.0 True False 75725.51845275397 92632.01847600273 87739.21924281177 76074.50141203836 86405.21039557457 86195.89971980941 95953.44300818178 86335.34410835845 84560.98622969328 85667.2123776527 0.8839498374118668 1.0813007206029606 1.0241866964927597 0.8880235425039147 1.0086147079779892 1.0061714082609117 1.1200719662171752 1.0077991534002575 0.9870869365623482 1.0 16.386455523314098 -6.721151317364384 3.3013432449526183 1.031861624962493 0.9788725268792982 0.12300275040706976 0.06484964395289625 0.5518307784318965 12.364540776846844 0.023578045166324953 0.022504640741444502 1.900416019502938e-07 6.721151317364384 -0.05298909808319485 IAESNHIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IAESNHIK 8 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ; 128.61 0.0030201 4764400.0 23926.0 37720.0 69536.0 72237.0 96512.0 89675.0 66576.0 56663.0 72076.0 49645.0 False True 27976.199239959562 41464.5923172045 71194.00195674843 68189.79508551398 77601.16641718902 84972.28513618468 60269.43931150051 55175.65628941113 73129.97514560456 58645.24551039624 0.4770412161545155 0.7070409878300182 1.2139773878877806 1.162750611614811 1.3232303103485583 1.4489202730189161 1.0276952340632002 0.9408376725037317 1.2469889845143638 1.0 15.839726530316215 -5.120799621657655 3.027660798877115 1.1800362747212234 0.5006206962653951 0.7194081857453882 0.1472534012378715 0.14544381545267246 2.4437083912905972 0.041840177394565733 0.1565807614756814 7.571821693453587e-06 5.120799621657655 -0.6794155784558283 IAESNHIK ddPTM_PC-9_Lapatinib_30min_R1 2 IAESNHIK 8 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ; 148.99 0.00068013 12361800.0 55004.0 67888.0 68557.0 82201.0 92888.0 107359.0 82801.0 65630.0 97127.0 51681.0 False True 54219.63287350177 67730.80950702634 62920.50809767307 88246.33575449737 87424.51046483437 102767.50583605247 87088.03063159548 68679.4093940943 86187.53446734752 60613.991989396156 0.8945068802428815 1.1174121235716532 1.0380525359339543 1.4558740128836132 1.442315669955024 1.6954419674921044 1.4367644791788454 1.1330619736464331 1.421908236672899 1.0 15.887363239974913 -5.754322798931931 24.52111047592165 1.3943201372899363 1.0267324973821812 0.4237121774343183 0.18679084785691957 121.66193602718464 419195.71023194556 0.0516418578183644 0.08701949733357763 1.7606669055204918e-06 5.754322798931931 -0.3675876399077551 IAFDAESEPNNSS(ph)GSMEK ddPTM_PC-9_AZD4547_30min_R2 1 IAFDAESEPNNSSGSMEK 18 0 H7C0N5;H7C0S6;H7C3P3;Q92556 H7C0N5 ELMO1 Engulfment and cell motility protein 1 1 IAFDAES(0.003)EPNNS(0.374)S(0.509)GS(0.114)MEK 71.143 0.0082026 4084500.0 19174.0 17380.0 24942.0 32932.0 28891.0 27569.0 21865.0 29351.0 27079.0 29382.0 True False 25270.93315602439 22997.74511557594 24611.2527831867 25340.03619432806 24879.983344960667 25845.106071810387 23810.942641882404 24815.47736888219 28510.340657125835 28353.34512318477 0.8912857740852643 0.8111122343998307 0.8680193704220767 0.893722983451688 0.8774972842486968 0.9115363975405014 0.8397930663360069 0.8752222096217623 1.0055371079941002 1.0 14.791231333691687 -8.254360537245814 7.294453186484053 1.0034104556679855 0.870073428174552 0.7937331372237231 0.026863631948720712 0.05252489733354991 21.585888937988056 0.02113950621534731 0.0069749262524945125 5.567233832741991e-09 8.254360537245814 -0.13333702749343346 IAFDAESEPNNSSGS(ph)MEK ddPTM_PC-9_Lapatinib_30min_R1 1 IAFDAESEPNNSSGSMEK 18 0 H7C0N5;H7C0S6;H7C3P3;Q92556 H7C0N5 ELMO1 Engulfment and cell motility protein 1 1 IAFDAESEPNNS(0.008)S(0.039)GS(0.954)MEK 157.62 1.0768e-17 0.0 25884.0 25996.0 21818.0 20255.0 21782.0 24050.0 19538.0 20035.0 22514.0 22231.0 True False 25514.88941345576 25935.807859189492 20024.208259915536 21744.620268699244 20500.82558505968 23021.43756328824 20549.582039831792 20965.89924136341 19978.236237069643 26073.598729054494 0.9785718373054445 0.9947153106367531 0.7679878971828326 0.8339708106525642 0.786267588072339 0.8829405485033736 0.7881375430133031 0.8041045449549149 0.7662247334813576 1.0 14.670302099755025 -5.251616790813103 24.510859758868758 0.820868644009839 0.9866436089001303 0.4693180310672115 0.06676441104572108 392.1483945143745 978543.0093195604 0.015625005275237757 0.04023191971484322 5.602517337679345e-06 5.251616790813103 0.1657749648902912 IAGEASR ddPTM_PC-9_AZD4547_30min_R2 4 IAGEASR 7 0 Q16778;P33778;P23527;P06899;Q6DRA6;Q6DN03;U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;O60814;P57053 Q16778;U3KQK0 HIST2H2BE;HIST1H2BB;HIST1H2BO;HIST1H2BJ;HIST2H2BD;HIST2H2BC;HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BK;H2BFS Histone H2B type 2-E;Histone H2B type 1-B;Histone H2B type 1-O;Histone H2B type 1-J;Putative histone H2B type 2-D;Putative histone H2B type 2-C;Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-K;Histone H2B type F-S 0 ;;; 128.82 0.020505000000000002 104771000.0 236474.0 185974.0 180352.0 195373.0 157196.0 163115.0 130126.0 155516.0 242624.0 344952.0 False True 311667.8130352415 246086.4585802141 177960.4146400965 150332.77333276023 135372.04880047188 152915.3932642949 141706.9619125358 131484.575602163 255448.60931328722 332875.33547521674 0.9362898954057406 0.7392751350258444 0.5346158025978047 0.4516188413843982 0.406674915121642 0.4593773613355615 0.42570580277518394 0.39499644938984163 0.7674002309261087 1.0 18.344622451836464 -8.521744682262439 4.781048975720645 0.9995301948232526 0.5365323836391902 0.444894548582623 0.16238298366902493 0.15151076765381524 12.64312992642123 0.1719251654798277 0.0447782747682941 3.007844066855466e-09 8.521744682262439 -0.46299781118406236 IAGEASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IAGEASR 7 0 Q16778;P33778;P23527;P06899;Q6DRA6;Q6DN03;U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;O60814;P57053 Q16778;U3KQK0 HIST2H2BE;HIST1H2BB;HIST1H2BO;HIST1H2BJ;HIST2H2BD;HIST2H2BC;HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BK;H2BFS Histone H2B type 2-E;Histone H2B type 1-B;Histone H2B type 1-O;Histone H2B type 1-J;Putative histone H2B type 2-D;Putative histone H2B type 2-C;Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-K;Histone H2B type F-S 0 128.48 0.020569999999999998 7900600.0 17474.0 25103.0 28973.0 18128.0 54196.0 53844.0 22661.0 42013.0 47710.0 54783.0 False True 20432.003072768246 27595.059940052586 29663.82620071438 17112.346931768963 43576.68284924126 51020.32585305527 20514.386028567536 40910.20326645308 48407.668491547716 64714.72423801061 0.31572417735448494 0.4264108402681634 0.45837831420891906 0.2644274101954361 0.6733658122218531 0.7883882138693894 0.31699719453518554 0.6321622126672712 0.748016298632625 1.0 15.981806378758925 -10.861513851863144 0.09754097850799619 1.8532322683681346 1.873830250941385e-12 0.6058573755652905 0.1449910842142193 48.42477710963846 0.8267945685916657 13.711359454451335 3.8658706545816366 1.375580935292947e-11 10.861513851863144 -1.8532322683662608 IAGHPLAQNER ddPTM_PC-9_Lapatinib_30min_R1 2 IAGHPLAQNER 11 0 A0A087X0R6;Q9UMY4-3;Q9UMY4;Q9UMY4-1 A0A087X0R6 SNX12 Sorting nexin-12 0 ; 82.417 0.011724 3581100.0 30979.0 24905.0 26936.0 23100.0 26821.0 27289.0 24332.0 20910.0 27941.0 22793.0 False True 30537.233779147176 24847.334002658634 24721.426055966847 24798.85105934101 25243.441512114845 26121.913083766012 25591.79190260963 21881.554935707973 24793.99034822614 26732.73968023659 1.1423159071766682 0.9294720369056737 0.924762158748858 0.9276584201983122 0.9442893550778569 0.9771506174160608 0.9573202076826246 0.8185302066845367 0.9274765940490656 1.0 14.706320077981495 -4.761303085233519 24.975658837846833 0.9303027909070202 1.1423161385247271 0.654692799442493 0.04529620778960684 1.9896999692478796 363301.4599960863 0.011535623300295826 0.06473516393365825 1.732594433530837e-05 4.761303085233519 0.21201334761770696 IAGPGLGSGVR ddPTM_PC-9_Lapatinib_30min_R1 2 IAGPGLGSGVR 11 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 115.49 0.006237899999999999 9781300.0 57913.0 51274.0 53334.0 52653.0 52559.0 50638.0 51901.0 36386.0 46234.0 43642.0 False True 57087.1500000565 51155.27820326519 48949.08439519364 56525.27726525902 49467.58295496977 48472.33078294342 54588.17982645665 38076.626393623636 41026.640054396266 51185.46155069035 1.1153000924592924 0.9994103140518666 0.9563083522597141 1.104322898588704 0.9664381536538589 0.9469941134542659 1.0664782180853543 0.7438953413737477 0.8015291610444203 1.0 15.643446472446804 -7.7546690420296045 24.999472068186414 0.8295341795501218 1.016893481533043 0.475933462720849 0.08268689858842576 118.5913934957559 437903.1252771068 0.0384630776910485 0.02156401676761466 1.7592637658474375e-08 7.7546690420296045 0.18735930198292128 IAGVDY(ph)VY(ph)FVQKNS(ph)LNS(ph)RER ddPTM_PC-9_Lapatinib_30min_R1 1 IAGVDYVYFVQKNSLNSRER 20 2 K7ESI4;K7ELM0;K7EJ08;Q92503-3;Q92503;Q92503-2 K7ESI4 SEC14L1 SEC14-like protein 1 4 IAGVDY(1)VY(1)FVQKNS(1)LNS(1)RER 41.208 0.041527 11800000.0 0.0 958.87 855.11 1235.1 1625.4 0.0 0.0 0.0 0.0 0.0 True False 0.0 956.6497954277975 784.8061566200554 1325.9333741728178 1529.7971676593518 0.0 0.0 0.0 0.0 0.0 0.0 IAHFLDR ddPTM_PC-9_AZD4547_30min_R2 2 IAHFLDR 7 0 P60228;E5RIP5;E5RJ25;E5RII3;H0YBR5;E5RHS5 P60228 EIF3E Eukaryotic translation initiation factor 3 subunit E 0 ; 117.93 0.0059954 7287100.0 44338.0 34657.0 54094.0 68967.0 61290.0 54715.0 45844.0 55151.0 46012.0 58115.0 False True 58436.56171230881 45859.19749542666 53376.67821560832 53067.723679528244 52780.94144240901 51293.66240048987 49924.02718840417 46628.68019390219 48444.10038464026 56080.41153882931 1.0420137817970208 0.8177400314488489 0.9517882759945697 0.9462791413858452 0.9411653729727751 0.9146448999393458 0.890222197350272 0.83146109157236 0.863832826032281 1.0 15.775209315967345 -7.136443597657727 2.977285347114815 0.8820189079961008 0.9337007964042079 0.0700165635242348 0.06526544750278693 0.6026700123997698 10.220190640276341 0.02624045842827512 0.019526123760667792 7.303926636802845e-08 7.136443597657727 0.05168188840810706 IAHFLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IAHFLDR 7 0 P60228;E5RIP5;E5RJ25;E5RII3;H0YBR5;E5RHS5 P60228 EIF3E Eukaryotic translation initiation factor 3 subunit E 0 ; 134.66 0.0033439999999999998 5321300.0 46146.0 47576.0 47700.0 54919.0 60534.0 59315.0 58785.0 47562.0 49296.0 44306.0 False True 53957.60637495499 52299.03086116967 48837.34890325737 51842.06647980029 48672.797246954964 56204.41698191022 53216.45923345588 46313.547896104545 50016.86074113048 52338.32707389696 1.0309386904700213 0.9992491885980267 0.933108710836391 0.9905182182572249 0.9299647116774176 1.0738672809040055 1.0167779944192537 0.8848878152088053 0.9556450031448506 1.0 15.675580190814175 -7.737007685020994 24.999113957157643 0.940199722986885 0.9942300972969127 0.17819469083766337 0.04793421725370449 353.5948905358624 361807.40252504084 0.02295186610012834 0.01324348300284938 1.832281999094373e-08 7.737007685020994 0.05403037431002766 IAHFLDR ddPTM_PC-9_Lapatinib_30min_R1 2 IAHFLDR 7 0 P60228;E5RIP5;E5RJ25;E5RII3;H0YBR5;E5RHS5 P60228 EIF3E Eukaryotic translation initiation factor 3 subunit E 0 ; 117.93 0.0059954 6062400.0 42036.0 39852.0 43983.0 38105.0 41751.0 39513.0 38304.0 33443.0 44788.0 34313.0 False True 41436.5589315417 39759.72514249957 40366.887519289805 40907.368814553665 39295.288265624215 37823.121099301796 40287.19369708861 34996.8838696739 39743.50380145134 40243.95633080145 1.0296343279705698 0.9879676047672464 1.0030546496839892 1.016484772975575 0.9764270675233997 0.9398459929833782 1.0010743816023393 0.8696183740485871 0.9875645295597572 1.0 15.296484521130663 -6.474579987190753 3.949119930129543 0.9541344483489681 1.0070009230999786 0.27801295431957507 0.037121842475800804 0.2775607874692213 8.974711400061723 0.011616238978141636 0.01277424708535407 3.352895460358007e-07 6.474579987190753 0.05286647475101047 IAILTCPFEPPKPK ddPTM_PC-9_Lapatinib_30min_R1 1 IAILTCPFEPPKPK 14 1 E7ENZ3;B7ZAR1;E9PCA1;P48643-2;P48643 E7ENZ3 CCT5 T-complex protein 1 subunit epsilon 0 145.83 0.00024514 2802200.0 39701.0 34252.0 36760.0 32449.0 40299.0 35000.0 33185.0 31647.0 35305.0 36773.0 False True 39134.85645972825 34172.6915984366 33737.734697703505 34835.40770669078 37928.69205088238 33503.13158898497 34903.15692454797 33117.435153053535 31328.579121868333 43129.16405305752 0.9073873171199084 0.7923337339995122 0.782248750664384 0.8076995803544035 0.87942098771547 0.7768092038085738 0.8092704250332812 0.7678663818364866 0.7263896671711026 1.0 15.396376132992694 IAIS(ph)PLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IAISPLK 7 0 Q6MZP7-3;Q6MZP7 Q6MZP7-3 LIN54 Protein lin-54 homolog 1 IAIS(1)PLK 94.85 0.015281999999999999 0.0 39913.0 61919.0 40571.0 45047.0 45214.0 30606.0 43648.0 31477.0 27251.0 31130.0 True False 46669.48258231657 68065.90911158483 41538.3665063743 42523.1626343445 36354.64127141476 29000.967481216274 39513.34545584558 30650.762102638324 27649.49432117307 36773.6225750556 1.2691021257713555 1.850943810952025 1.1295696098907249 1.156349569519674 0.9886064718593962 0.7886350446444269 1.0745023929910131 0.8334985774131877 0.7518838880977793 1.0 15.16638368319534 -5.700634185657233 1.4685034331062283 0.9004001846434476 1.5586242497491083 0.6396467543691222 0.18071893135552125 0.24546307490385 1.0533221961518138 0.05611697737190194 0.1410147448493745 1.9923508266619667e-06 5.700634185657233 0.6582240651056607 IALESEGRPEEQMESDNCS(ph)GGDDDWTHLSSK ddPTM_PC-9_AZD4547_30min_R2 1 IALESEGRPEEQMESDNCSGGDDDWTHLSSK 31 1 Q13501;Q13501-2 Q13501 SQSTM1 Sequestosome-1 1 IALES(0.002)EGRPEEQMES(0.376)DNCS(0.621)GGDDDWT(0.001)HLSSK 64.289 6.2518e-05 15289000.0 4802.5 12284.0 56046.0 143460.0 86903.0 76578.0 29527.0 99360.0 40054.0 61857.0 True False 6329.595101794464 16254.562773287396 55302.79342019416 110387.5134349055 74838.01850497078 71789.56555432173 32154.845798621656 84006.19506565816 42171.17266813835 59691.40525780545 0.10603863444757461 0.2723099364654662 0.9264783293565129 1.8493033118946527 1.2537486457513867 1.2026784299056905 0.5386846843317863 1.4073415544974666 0.7064865115170649 1.0 15.865235597729908 -5.291048563752598 3.6861462130597467 1.1505602614705368 0.15755777448108788 0.5411749857682533 0.3434901914572953 0.16423315208296801 4.815981553652276 0.09353358539417865 0.2380953677353456 5.116246213646453e-06 5.291048563752598 -0.9930024869894489 IALESEGRPEEQMESDNCS(ph)GGDDDWTHLSSK ddPTM_PC-9_Lapatinib_30min_R1 2 IALESEGRPEEQMESDNCSGGDDDWTHLSSK 31 1 Q13501;Q13501-2 Q13501 SQSTM1 Sequestosome-1 1 IALES(0.01)EGRPEEQMES(0.095)DNCS(0.877)GGDDDWT(0.016)HLS(0.001)SK;IALES(0.002)EGRPEEQMES(0.103)DNCS(0.886)GGDDDWT(0.007)HLS(0.001)S(0.001)K 46.771 0.007272 12102300.0 14272.099999999999 17576.5 33776.0 19172.9 28481.0 33458.7 24597.8 27000.2 35424.0 20146.0 True False 14068.577236817402 17535.80269414694 30999.06765913041 20582.939024919466 26805.80357580041 32027.74939703918 25871.35372604024 28254.72786107612 31434.17608874278 23628.20925714237 0.5954144507402621 0.7421553831400147 1.311951630433439 0.8711171803549871 1.1344830784287012 1.35548780055593 1.0949350179053374 1.1958048768564735 1.3303664169658058 1.0 14.528222673535895 -5.131788271239875 4.578933832238969 1.1611119437412891 0.6278828247537606 0.6541252973873046 0.1446732913170838 0.127526236929449 4.084804024636433 0.037080602881139346 0.10900504704649631 7.3826406347879135e-06 5.131788271239875 -0.5332291189875286 IALLEEARR ddPTM_PC-9_AZD4547_30min_R2 2 IALLEEARR 9 1 P15311;E7EQR4 P15311 EZR Ezrin 0 ; 134.77 0.0006939 6324100.0 19141.0 14293.4 23335.0 55233.0 34138.0 24842.0 21629.0 24761.0 18276.2 25947.0 False True 25227.439842467025 18913.462027328715 23025.562653181853 42499.88519134346 29398.52796477335 23288.625812902672 23553.93909907499 20934.756401175153 19242.24262039821 25038.603427652153 1.007541811002379 0.7553720830308391 0.9196025137629227 1.697374428815283 1.1741281038185294 0.9301088169791115 0.940704986487484 0.836099204241368 0.7685030307699768 1.0 14.611866475198985 -6.882833984079565 4.960169110958204 0.8809932454694909 1.112183134633115 0.17457825431243845 0.23547923582536243 0.4312544192349976 16.929289133085724 0.09425469557972116 0.08305277324390108 1.3096824741187558e-07 6.882833984079565 0.23118988916362415 IALLEEARR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IALLEEARR 9 1 P15311;E7EQR4 P15311 EZR Ezrin 0 114.89 0.0012729000000000002 2764400.0 9666.8 6362.4 7520.6 13353.0 9075.6 14188.0 10583.0 13124.0 13993.0 11024.0 False True 11303.198311997026 6994.0170243632465 7699.919626034324 12604.874701010094 7297.301329739723 13443.956303453457 9580.501625715118 12779.508906027431 14197.62115284483 13022.563934064015 0.8679702683148649 0.5370691255405178 0.5912752408066982 0.967925729897064 0.5603582648307581 1.0323586331787689 0.7356847448953383 0.9813358545009091 1.0902324016015876 1.0 13.66872589954309 -7.2624398530090595 0.6792833294663306 1.0482544576870598 0.6821668660578258 0.37932484159663993 0.15853301540133496 0.7449441003465216 0.6861156798094138 0.13266696182555907 0.08897250708910663 5.4646222614308345e-08 7.2624398530090595 -0.366087591629234 IALLEEARR ddPTM_PC-9_Lapatinib_30min_R1 1 IALLEEARR 9 1 P15311;E7EQR4 P15311 EZR Ezrin 0 117.53 0.00049881 0.0 28867.0 9217.6 13276.0 11552.0 12047.0 8955.4 6278.9 5277.1 15729.0 7281.6 False True 28455.351286440527 9196.257213527659 12184.498526842 12401.572616342311 11338.419145313288 8572.39841805702 6603.990719106345 5522.293331000692 13957.434386287134 8540.214857877887 3.3319245194624116 1.0768180153037494 1.4267203729192433 1.4521382450820346 1.327650338311361 1.0037684719547126 0.7732815659801018 0.6466222949773535 1.634318880562139 1.0 13.06005665081882 -4.760348522489921 24.999925349692262 1.1454416192711565 3.331927114870861 0.8299526316755036 0.29641852598811613 11.174172433451687 255969.67920830607 0.07844390631135778 0.467704060492963 1.736406798341244e-05 4.760348522489921 2.1864854955997046 IALTDNALIAR ddPTM_PC-9_Lapatinib_30min_R1 2 IALTDNALIAR 11 0 A8MUD9;P18124 A8MUD9 RPL7 60S ribosomal protein L7 0 ; 136.96 0.00037891 20584000.0 58402.0 49661.0 50367.0 50864.0 49511.0 53847.0 52204.0 38938.0 44978.0 47474.0 False True 57569.17677038489 49546.01300566272 46226.01968224244 54604.708237329956 46598.86032237123 51544.08933348781 54906.867683866265 40747.20163015764 39912.10400066265 55679.817644871306 1.0339325666898553 0.889837917962837 0.830211405810887 0.9806912189548024 0.8369075599273891 0.9257230270084328 0.9861179509255049 0.7318127708327881 0.7168145602635423 1.0 15.764866865821029 -7.762796689680193 24.999929071439887 0.7932352496514785 0.9197552334429271 0.20850649081937345 0.09451492062991261 47.674319555523645 878032.4746577288 0.046381291001804825 0.024200921204330924 1.7266460136949728e-08 7.762796689680193 0.12651998379144858 IANLQTDLSDGLR ddPTM_PC-9_Lapatinib_30min_R1 2 IANLQTDLSDGLR 13 0 Q60FE5;P21333-2;P21333;A0A087WWY3;F8WE98 Q60FE5 FLNA Filamin-A 0 ; 120.63 0.00096582 9490400.0 36967.0 34577.0 36547.0 35170.0 35517.0 37175.0 34633.0 36687.0 37224.0 33315.0 False True 36439.84380108248 34496.93908090456 33542.24673549973 37756.51912368069 33427.95988910866 35585.11190915757 36426.12727942952 38391.61195247814 33031.44113390246 39073.45336055286 0.9325984950659831 0.8828740772560281 0.8584408044506954 0.9662959343593188 0.8555158813491595 0.9107234925153301 0.9322474505466675 0.9825497531077433 0.8453678467859664 1.0 15.253901147893492 -14.522878745266848 0.21240317746726184 1.438546989179161 0.8961781215755522 0.2581859261099644 0.04527706344542447 198.96991416131328 1.9803752399742411 37.27886034871803 0.09085062343899576 3.0000000000931844e-15 14.522878745266848 -0.5423688676036087 IANS(ph)MVSTWTGPPAMK ddPTM_PC-9_AZD4547_30min_R2 1 IANSMVSTWTGPPAMK 16 0 Q6P1X5 Q6P1X5 TAF2 Transcription initiation factor TFIID subunit 2 1 IANS(1)MVSTWTGPPAMK 68.277 0.020708 11234000.0 32776.0 27919.0 37134.0 54689.0 45143.0 45965.0 37495.0 48131.0 34378.0 39903.0 True False 43198.08621684859 36943.27076419823 36641.578897075415 42081.295986627236 38875.67367490078 43090.80128371595 40831.982362560295 40693.4598903502 36195.150895921994 38506.00811552794 1.12185314268992 0.9594157528185966 0.9515808231053513 1.0928501303062241 1.0096002046814032 1.1190669558483561 1.0604054889318528 1.056808064036639 0.9399870998657461 1.0 15.232795947492441 IANS(ph)MVSTWTGPPAMK ddPTM_PC-9_Lapatinib_30min_R1 1 IANSMVSTWTGPPAMK 16 0 Q6P1X5 Q6P1X5 TAF2 Transcription initiation factor TFIID subunit 2 1 IANS(0.998)MVSTWT(0.001)GPPAMK 63.185 0.030327 12743000.0 34408.0 33021.0 42992.0 33488.0 45542.0 42783.0 41342.0 40271.0 40306.0 35073.0 True False 33917.33561034559 32944.5419033042 39457.36371391917 35950.81923269315 42863.30909901696 40953.27082204411 43482.48647204043 42142.13767651338 35766.313839003706 41135.32131816509 0.8245307080017364 0.8008820849724614 0.9592088368225545 0.8739647116070418 1.0420073971827417 0.9955743509400864 1.057059604219959 1.0244757139627274 0.8694793839670223 1.0 15.328090092349342 -5.511364974790455 1.1063138566180357 0.999352215803413 0.7940784498552637 0.55215835102566 0.05989342525938861 0.4936496805828343 1.0252667963784248 0.02089679457558227 0.08898607334166748 3.0805979722081876e-06 5.511364974790455 -0.2052737659481494 IAPELYHK ddPTM_PC-9_Lapatinib_30min_R1 1 IAPELYHK 8 0 Q15046;Q15046-2 Q15046 KARS Lysine--tRNA ligase 0 73.665 0.023778 0.0 18772.0 22038.0 21827.0 22983.0 21536.0 22199.0 22749.0 18412.0 23965.0 21452.0 False True 18504.30783763681 21986.972365010683 20032.468314656544 24673.24648904046 20269.294821405063 21249.60051839648 23926.831908288117 19267.48873631061 21265.80933736227 25159.94961700677 0.7354668081341823 0.8738877740100351 0.7962046275766655 0.9806556398015469 0.8056174646591547 0.844580408222793 0.9509888641476003 0.7657999729572919 0.8452246392014923 1.0 14.618841412761594 -12.151902434106605 2.042032392612348 3.937602311099085 0.8474415636851703 0.29178111043667165 0.07263519335984907 2808941.5316095506 164808.95033605487 38187734.214757204 0.018881114202635788 7.048513987070138e-13 12.151902434106605 -3.0901607474139148 IAQLEEQLDNETK ddPTM_PC-9_AZD4547_30min_R2 2 IAQLEEQLDNETK 13 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 171.62 0.00083894 6198800.0 22810.0 20134.8 30445.0 23763.0 29979.0 21526.0 20981.0 26611.0 25045.0 24003.0 False True 30063.105522526148 26642.98034252581 30041.27940759038 18284.8074846902 25816.933325207683 20179.975817105824 22848.268354417327 22498.88140994598 26368.827569619138 23162.662275944604 1.2979123541315862 1.1502555287090492 1.2969700567965154 0.7894087159263959 1.1145926585485664 0.871228685921116 0.9864266931934769 0.9713426350524488 1.1384195502001628 1.0 14.499513463255004 -5.74139116238515 24.99971060703364 0.9815769464077784 1.2385670221807163 0.5831683771229668 0.10324614256398013 166.88042773973288 208094.79116154823 0.02631266102828903 0.04550063898344426 1.8138811918168148e-06 5.74139116238515 0.256990075772938 IAQLEEQLDNETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IAQLEEQLDNETK 13 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 169.62 0.0011532 5353400.0 24147.0 23269.0 17893.4 18334.8 26011.0 18671.2 24042.5 23306.0 17995.3 18457.7 False True 28234.610175010588 25578.992540536354 18320.046517097384 17307.560598223627 20914.331271525843 17692.04940323091 21765.020347373695 22694.24219474817 18258.447218737132 21803.93489892719 1.2949318692196152 1.17313653058994 0.8402174470810211 0.793781520558255 0.9591998585794201 0.8114154387840061 0.9982152509749326 1.0408324139632608 0.837392301131641 1.0 14.412300897436692 -5.114108034989473 3.9852444720849176 0.9094258537580949 1.2720926616300758 0.7105017062429215 0.08405721887753421 0.11930793809838648 3.19685424183582 0.02246704777700992 0.0709852136926471 7.689391353812011e-06 5.114108034989473 0.3626668078719809 IAQLEEQLDNETK ddPTM_PC-9_Lapatinib_30min_R1 2 IAQLEEQLDNETK 13 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 101.32 0.009362 14001100.0 40703.0 42790.0 50996.0 44363.0 43318.0 40304.0 47109.0 37860.0 42834.0 41934.0 False True 40122.56775598395 42690.92238400975 46803.30573025264 47625.60301062972 40770.12040646475 38580.29187321286 49548.073513892705 39619.11381472516 38009.58385798351 49182.23602645727 0.8157938922175128 0.868015076846942 0.9516302940166264 0.96834969001836 0.8289602852650442 0.7844354992818715 1.0074384069735796 0.8055573925799614 0.7728315531960869 1.0 15.585849706816683 -6.303053613467948 24.949131064145234 0.8597550446370867 0.9022153270278083 0.033408285450209796 0.08605078509183701 1703.9037776921405 1021543.5840960399 0.02707538998880903 0.030700950220935393 4.976756433413368e-07 6.303053613467948 0.04246028239072153 IAQLEEQLDNETKER ddPTM_PC-9_AZD4547_30min_R2 2 IAQLEEQLDNETKER 15 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 155.09 0.00024199 10279100.0 28351.0 15771.8 28513.0 64610.0 49883.0 35933.0 31130.0 29932.0 26853.0 43682.0 False True 37366.028262566375 20869.72591564102 28134.898989936755 49715.16271454929 42957.60649325645 33686.103829604355 33900.50969319917 25306.697168934017 28272.39475851399 42152.70647576603 0.8864443445416357 0.49509812442622664 0.6674517804950855 1.1794061845858221 1.0190948597322729 0.7991445068650764 0.8042309148687494 0.600357587560435 0.670713629616358 1.0 15.363337644021964 -10.690191152908165 15.162936668828838 0.9999999949081919 0.792076757970167 0.09673815432852406 0.1912791583702919 0.0 0.0 0.20328445205179624 0.049303721271209515 2.0408394799555566e-11 10.690191152908165 -0.20792323693802495 IAQLEEQLDNETKER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IAQLEEQLDNETKER 15 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 137.39 5.3447e-05 2540800.0 7220.6 3633.3 4896.9 9058.5 12091.0 11306.0 9695.0 10704.0 10511.0 9530.2 False True 8442.904966649336 3993.990012356815 5013.660667596665 8550.98161305324 9721.855345969738 10713.093456924502 8776.619414278377 10423.031341825475 10664.703490141645 11257.949818978303 0.7499504885353591 0.3547706355578056 0.44534402339800727 0.7595505176829142 0.8635546882240437 0.9516025234776496 0.7795930480595165 0.925837431274978 0.9473042304881674 1.0 13.458656502234268 -5.949818651336111 3.1346166183068607 0.9005870539150381 0.5011124067826634 0.719130991996533 0.10966341630507451 0.12779250829576605 2.5698566319845693 0.032242443966714995 0.04926949475092208 1.1224870742012857e-06 5.949818651336111 -0.3994746471323747 IAQLEEQLDNETKER ddPTM_PC-9_Lapatinib_30min_R1 1 IAQLEEQLDNETKER 15 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 78.902 0.014805 2667200.0 18193.0 10294.0 15058.0 6736.4 10398.0 9717.4 5606.9 7818.1 9128.4 7232.6 False True 17933.564483812417 10270.164875461469 13819.989365560918 7231.81732797164 9786.410083254548 9301.80945436578 5897.1978472276 8181.357467377256 8100.263465686529 8482.745273166282 2.114122716915972 1.2107123984907793 1.6291883017256332 0.8525326524713952 1.1536843047983756 1.0965564984947114 0.6951992140896155 0.9644704873147124 0.9549106102844243 1.0 13.050315524807873 -1.5228787452817039 0.5245721219075843 0.9236582372881561 42.16995690002191 0.722188066346004 0.20771745110007417 61.02368075413623 0.6043498340108204 0.10331868771391443 2806.0725896963518 0.02999999999990562 1.5228787452817039 41.24629866273375 up IAQLS(ph)ESPVILTPNAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IAQLSESPVILTPNAK 16 0 Q6P4F7-3;Q6P4F7;H3BQ41;H3BR51;Q6P4F7-2 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 1 IAQLS(0.991)ES(0.009)PVILTPNAK 149.33 3.0592e-05 4359800.0 23683.0 19679.0 17590.0 22472.0 22639.0 17163.0 24348.0 21477.0 19559.0 14471.0 True False 27692.064139428334 21632.60106601982 18009.41231044647 21212.96669520698 18203.050465421304 16262.942066265286 22041.581175745232 20913.2515067625 19845.01337300736 17094.477747627032 1.619942097574312 1.2654730600952548 1.053522229595253 1.2409251109266355 1.064849756404413 0.9513564734975788 1.2893977517859492 1.2233922448824486 1.1609019980597035 1.0 14.06124272730363 -4.80089474948367 2.8631726756704245 1.1331506269915121 1.6949162403820461 0.6759898207943558 0.10375245905038871 0.23648015770026615 2.8034334240349192 0.027228403000001095 0.3078742460477604 1.581631298436254e-05 4.80089474948367 0.561765613390534 IAQLSES(ph)PVILTPNAK ddPTM_PC-9_AZD4547_30min_R2 1 IAQLSESPVILTPNAK 16 0 Q6P4F7-3;Q6P4F7;H3BQ41;H3BR51;Q6P4F7-2 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 1 IAQLS(0.038)ES(0.59)PVILT(0.372)PNAK 170.09 3.07e-05 5487500.0 20458.0 24549.0 33906.0 40989.0 36955.0 30656.0 28252.0 30384.0 27262.0 36021.0 True False 26963.218447165287 32483.984168140054 33456.384286213164 31539.61932373718 31824.436139732825 28739.075473808236 30766.373268623927 25688.850954860718 28703.013663523932 34759.915753939116 0.7756986132542545 0.9345242490830507 0.9624990038251681 0.9073560346636629 0.9155498639586422 0.8267878345059402 0.8851106972299659 0.73903662876253 0.8257503806024388 1.0 15.085136965110234 -6.7594716168674 24.92334931074179 0.8408877428731699 0.9050701492660166 0.057017111802390774 0.076871087900849 103.2567365495324 1307836.1992713197 0.025473122089427844 0.024263916863648947 1.7399164058250718e-07 6.7594716168674 0.06418240639284667 IAQLSES(ph)PVILTPNAK ddPTM_PC-9_Lapatinib_30min_R1 1 IAQLSESPVILTPNAK 16 0 Q6P4F7-3;Q6P4F7;H3BQ41;H3BR51;Q6P4F7-2 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 1 IAQLS(0.139)ES(0.503)PVILT(0.358)PNAK 166.77 4.765e-05 3829500.0 14743.0 19572.0 16794.0 18555.0 20061.0 18854.0 14807.0 15410.0 20040.0 13918.0 True False 14532.762116464919 19526.682236500106 15413.262146714713 19919.596597665484 18881.051421443502 18047.65837082063 15573.63400879257 16126.00485697081 17782.88416944461 16323.707755430738 0.890285609997521 1.196216112727439 0.9442255630671207 1.2202862790800961 1.1566643868126076 1.1056102352001709 0.9540500382709544 0.9878886034091027 1.0893900108894328 1.0 13.99468116681134 -7.243217814532058 24.259065179763464 1.0068228776281793 1.0935116832194636 0.11911883345381624 0.10215144935124312 1107.9127646761792 1475008.269621896 0.03789915464528244 0.02928976998577796 5.711920911422443e-08 7.243217814532058 0.08668880559128422 IAQLSESPVILT(ph)PNAK ddPTM_PC-9_AZD4547_30min_R2 1 IAQLSESPVILTPNAK 16 0 Q6P4F7-3;Q6P4F7;H3BQ41;H3BR51;Q6P4F7-2 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 1 IAQLS(0.008)ES(0.026)PVILT(0.967)PNAK 198.67 1.1649000000000003e-11 4945000.0 25749.0 21337.0 29556.0 35524.0 34975.0 39211.0 33079.0 41274.0 31508.0 32215.0 True False 33936.64638752855 28233.767982223475 29164.06812845267 27334.490640328873 30119.324962445007 36759.129971408365 36022.96691748585 34896.051682165635 33173.44855514312 31087.16265548285 1.0916611066640118 0.9082130876696101 0.9381386282066818 0.8792854768786009 0.9688669659639347 1.1824536828524346 1.1587730703088939 1.1225228905221754 1.0671108496706858 1.0 14.924031326570558 -6.675032570709685 6.700639732451248 1.1167083274086749 0.9473000073977083 0.5249595607334999 0.07034153513172643 0.1574624609431411 10.089454815965956 0.023124245115566777 0.023038804838368034 2.113330540800713e-07 6.675032570709685 -0.16940832001096662 IAQLSESPVILT(ph)PNAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IAQLSESPVILTPNAK 16 0 Q6P4F7-3;Q6P4F7;H3BQ41;H3BR51;Q6P4F7-2 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 1 IAQLS(0.005)ES(0.004)PVILT(0.991)PNAK 96.666 0.0056092 5295700.0 30434.0 26424.0 26703.0 31142.0 40588.0 33474.0 28596.0 32166.0 34731.0 25069.0 True False 35585.87510110045 29047.20008986775 27339.70079169145 29397.21470372626 32635.072763395892 31718.564512390833 25887.179862888544 31321.676582694156 35238.87517040335 29613.8112539052 1.2016648176754927 0.9808666584932484 0.9232077748211533 0.9926859616845035 1.1020220424715603 1.0710733664248662 0.8741590077999426 1.057671243803978 1.1899473143888686 1.0 14.853982554741393 -8.001921454945219 24.99848661672412 1.1045855495194918 1.015668752434607 0.08373710956961666 0.09677773552209273 147.9018583794322 1924220.3534223384 0.053977260001059506 0.025331112176946807 9.955854593432735e-09 8.001921454945219 -0.08891679708488476 IAQLSESPVILT(ph)PNAK ddPTM_PC-9_Lapatinib_30min_R1 1 IAQLSESPVILTPNAK 16 0 Q6P4F7-3;Q6P4F7;H3BQ41;H3BR51;Q6P4F7-2 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 1 IAQLS(0.055)ES(0.024)PVILT(0.922)PNAK 161.86 0.00014780000000000001 3711400.0 14387.0 20631.0 20736.0 15178.0 21639.0 22011.0 16259.0 19987.0 17652.0 14615.0 True False 14181.838741747319 20583.230187064873 19031.166123274746 16294.240752323716 20366.236563910854 21069.64084014709 17100.81146410202 20915.66898613079 15663.845876199412 17141.18327673661 0.8273547113281493 1.2008056768752764 1.1102597653863926 0.9505901949276551 1.1881464794528607 1.2291824024040416 0.9976447476243147 1.220199833842088 0.9138135695368133 1.0 14.065179083431408 -1.5577662189429624 20.553324507710983 1.0780830626196334 0.005377553703722171 0.0 0.13780755208636739 0.0 0.0 0.0296624365225779 0.0 0.027684314932061742 1.5577662189429624 -1.0727055089159112 IAQVS(ph)PGPR ddPTM_PC-9_AZD4547_30min_R2 4 IAQVSPGPR 9 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 IAQVS(1)PGPR;IAQVS(1)PGPR;IAQVS(1)PGPR;IAQVS(1)PGPR 99.73200000000001 0.004046500000000001 321694000.0 394564.0 336818.0 573591.0 748454.0 654383.0 528054.0 424592.0 556826.0 464760.0 596551.0 True False 520027.14455896453 445687.83166502026 565984.8085622984 575909.4937990294 563533.2159227927 495034.69990365225 462379.8654563056 470781.336288549 489326.2647736547 575665.9310659936 0.9033488287139043 0.7742126250891981 0.9831827419667374 1.0004230973554136 0.9789240347770206 0.8599339880804968 0.8032086675688629 0.8178030188737697 0.8500177592020101 1.0 19.134872307958354 -6.897493218551975 8.272443403734338 0.8496488941483412 0.9264031076314686 0.11953560484011372 0.07806295223027944 0.4672652993877683 33.84413391147831 0.02886834004541806 0.025464003289667244 1.2662130390973477e-07 6.897493218551975 0.07675421348312739 IAQVS(ph)PGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 IAQVSPGPR 9 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 IAQVS(1)PGPR;IAQVS(1)PGPR;IAQVS(1)PGPR;IAQVS(1)PGPR;IAQVS(1)PGPR 107.34 0.0025087 267665300.0 357675.0 406170.0 491058.0 474843.0 551436.0 505184.0 576899.0 503851.0 497960.0 375180.0 True False 418222.31309673714 446491.87331598555 502766.6850678345 448239.0861717769 443386.0743164476 478691.26171439484 522250.95033293375 490625.44512426166 505241.722952234 443197.1640767551 0.9436484413612071 1.0074339583063303 1.1344086240153892 1.0113762508059474 1.0004262442429794 1.080086472826556 1.1783715977083458 1.1070139542663966 1.139993131510051 1.0 18.757589124358454 -6.9590841805350685 5.6647309960479975 1.1172528132495219 1.0254614048854218 0.30386733066069327 0.061523910799681975 0.22340600640040706 17.866681910485966 0.0221655110291001 0.01925102237046611 1.0987928366479412e-07 6.9590841805350685 -0.09179140836410005 IAQVS(ph)PGPR ddPTM_PC-9_Lapatinib_30min_R1 2 IAQVSPGPR 9 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 IAQVS(1)PGPR;IAQVS(1)PGPR 87.713 0.010678 159072000.0 314232.0 265285.0 319269.0 288291.0 283985.0 283511.0 247823.0 267950.0 333970.0 256246.0 True False 309750.9940569087 264670.7488815621 293019.93523397966 309492.881850583 267281.5606359915 271385.89542642015 260654.06233274788 280399.93519956694 296354.78173999063 300537.7796736674 1.030655761126755 0.8806571645300276 0.9749853597512738 1.0297969266514158 0.8893442978324174 0.90300093293129 0.8672921674465474 0.9329939666954128 0.9860816236207681 1.0 18.19718683349941 -4.736926475543574 24.824708927456637 0.9371834724629389 1.0306562193047923 0.20570280333485902 0.05281835439821898 3600.0555504559184 3645643.243742269 0.01362772040054663 0.9111951149509807 1.8326246527148095e-05 4.736926475543574 0.09347274684185347 IAS(ph)DEEIQGTK ddPTM_PC-9_AZD4547_30min_R2 8 IASDEEIQGTK 11 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;A0A3B3ISX8;Q8WX93-4 Q8WX93-3 PALLD Palladin 1 IAS(1)DEEIQGTK;IAS(1)DEEIQGTK;IAS(1)DEEIQGTK;IAS(1)DEEIQGTK;IAS(1)DEEIQGTK;IAS(1)DEEIQGTK;IAS(1)DEEIQGTK;IAS(1)DEEIQGTK 217.46 8.712e-09 1236291800.0 462945.1 470160.0 559660.2 575963.8 522033.8 556675.1 558311.7 567953.3 581335.0 485629.9 True False 610152.011943728 622130.0255200921 552238.7400725211 443184.24446200475 449558.4178293084 521866.11799614155 608000.3597069221 480189.16775346483 612063.181281075 468628.14501523844 1.3019960888688997 1.327555828939515 1.178415649906311 0.9457055645848879 0.9593073369818411 1.1136038745158423 1.2974047038663281 1.0246699283028562 1.3060743102853383 1.0 18.838084077068423 -5.423212975616806 4.223510780876459 1.0951530780532543 1.311539874038748 0.3522892648281598 0.11908689975886555 0.25762476194824446 7.847923556245691 0.033046013542691946 0.07207108333763408 3.773870770001559e-06 5.423212975616806 0.2163867959854937 IAS(ph)DEEIQGTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 IASDEEIQGTK 11 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;A0A3B3ISX8;Q8WX93-4 Q8WX93-3 PALLD Palladin 1 IAS(1)DEEIQGTK;IAS(1)DEEIQGTK;IAS(1)DEEIQGTK;IAS(1)DEEIQGTK;IAS(1)DEEIQGTK;IAS(1)DEEIQGTK;IAS(1)DEEIQGTK 214.42 1.3632e-08 563730000.0 138911.3 158271.4 166866.7 183229.0 241563.0 244447.0 324697.0 295927.0 254367.0 217191.0 True False 162426.23946676383 173983.53861275702 170845.43497348408 172963.27316643303 194230.464224505 231627.7689956503 293939.3495572923 288159.2298105746 258086.63615991414 256566.00901698967 0.6330777802136995 0.6781238842953508 0.6658927097477312 0.6741472645933371 0.7570389583900148 0.9027999066716278 1.1456675445180573 1.1231387622804425 1.0059268456829127 1.0 17.968970522998056 -6.855033316528889 2.0578758733546123 1.0786984460555682 0.6672129122322581 0.9342996977183062 0.048697343049091645 0.07211409112466058 0.625849282178239 0.02014130131382919 0.01736833750286524 1.3962612439628784e-07 6.855033316528889 -0.4114855338233101 IAS(ph)DEEIQGTK ddPTM_PC-9_Lapatinib_30min_R1 6 IASDEEIQGTK 11 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;A0A3B3ISX8;Q8WX93-4 Q8WX93-3 PALLD Palladin 1 IAS(1)DEEIQGTK;IAS(1)DEEIQGTK;IAS(1)DEEIQGTK;IAS(1)DEEIQGTK;IAS(1)DEEIQGTK;IAS(1)DEEIQGTK 228.7 1.7991e-13 1041283000.0 191653.0 291560.0 270458.0 281478.0 423605.0 521080.0 614781.0 591874.0 588823.0 512549.0 True False 188919.99307514404 290884.91073339264 248221.98723807096 302178.8311030821 398689.38673947274 498794.6230968081 646611.3520334639 619374.626782268 522503.5531589258 601142.4117213868 0.3142682821765424 0.4838868545315846 0.4129171098197528 0.502674283515923 0.6632195282941614 0.8297445220484391 1.0756375518105195 1.030329277564484 0.8691843113559786 1.0 19.19734728292029 -6.602828758022581 1.3835443749811214 0.9996109824680849 0.4105817715623491 0.9346849842902843 0.06764452989082635 0.09580486195800382 0.3811627129625483 0.029742422237634326 0.03088531342405701 2.495578537654382e-07 6.602828758022581 -0.5890292109057358 down IAS(ph)DEEIQGTKDAVIQDLER ddPTM_PC-9_AZD4547_30min_R2 3 IASDEEIQGTKDAVIQDLER 20 1 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;A0A3B3ISX8;Q8WX93-4 Q8WX93-3 PALLD Palladin 1 IAS(0.998)DEEIQGT(0.002)KDAVIQDLER;IAS(0.892)DEEIQGT(0.108)KDAVIQDLER;IAS(1)DEEIQGTKDAVIQDLER 81.01 0.0006271 76812000.0 85088.0 33775.1 84331.0 243536.0 172280.0 100535.0 71338.0 91037.0 82512.0 111271.0 True False 112144.21405965403 44692.24056692111 83212.71583910349 187392.53779369235 148361.89576926464 94248.53055712805 77686.94379998212 76969.32347214497 86873.41586841333 107375.43615825663 1.0444121865485965 0.4162240654468764 0.7749697585997172 1.7452086296301652 1.3817116938235259 0.8777475922725815 0.7235075970772519 0.7168243150016431 0.8090622862790876 1.0 16.71230446602943 -6.986768472054527 24.899469949568594 0.7904472312591064 1.064172059233525 0.12047034429324432 0.3350622908154285 536.2204520145116 1009070.8005069792 0.13373078392951265 0.11787667016928123 1.0309355789157567e-07 6.986768472054527 0.27372482797441866 IAS(ph)DEEIQGTKDAVIQDLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IASDEEIQGTKDAVIQDLER 20 1 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;A0A3B3ISX8;Q8WX93-4 Q8WX93-3 PALLD Palladin 1 IAS(0.999)DEEIQGT(0.001)KDAVIQDLER;IAS(1)DEEIQGTKDAVIQDLER;IAS(0.969)DEEIQGT(0.031)KDAVIQDLER;IAS(0.995)DEEIQGT(0.005)KDAVIQDLER 90.87200000000001 0.00031329 34126100.0 34165.600000000006 10908.6 31500.4 64983.4 70647.2 106397.8 77446.0 129451.0 107933.0 70922.3 True False 39949.16127864089 11991.533715574147 32251.48900193224 61342.59077702537 56804.388305168555 100818.1120653779 70109.75421951567 126053.048414672 109511.31593582511 83779.9515693821 0.47683438018649504 0.14313130398080257 0.3849547343701109 0.732186992567365 0.6780188725476426 1.2033679917072488 0.8368321168275503 1.5045729444028333 1.3071303323102743 1.0 16.354317429776415 -6.384343487635854 0.8605565913781494 1.2498636948627333 0.2686982448225684 0.7608867277414981 0.20031906957229273 0.2770138810472814 0.44763591746179854 0.10632879500994509 0.15199097866135944 4.127209479471502e-07 6.384343487635854 -0.981165450040165 down IAS(ph)DEEIQGTKDAVIQDLER ddPTM_PC-9_Lapatinib_30min_R1 3 IASDEEIQGTKDAVIQDLER 20 1 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;A0A3B3ISX8;Q8WX93-4 Q8WX93-3 PALLD Palladin 1 IAS(0.997)DEEIQGT(0.003)KDAVIQDLER;IAS(0.997)DEEIQGT(0.003)KDAVIQDLER;IAS(1)DEEIQGTKDAVIQDLER 74.812 0.0011530999999999998 27691500.0 125130.5 43476.6 70741.4 60808.2 68737.0 89235.1 53015.1 47113.4 103422.4 56236.5 True False 123346.11612387645 43375.932603894355 64925.315161700906 65280.237878208725 64694.024802141525 85418.72279017798 55759.96247312343 49302.46055992267 91773.88022584657 65956.90409457397 1.8701016643688053 0.6576405184466918 0.9843596520025577 0.9897407826268652 0.9808529628585715 1.295068711346703 0.8453999355877984 0.7474950687380519 1.391421891092012 1.0 16.009236062251038 -4.747951934322179 24.99970072111426 0.9849642552032074 1.8701038305333557 0.611613268103196 0.21086717922318313 452.1045347619374 837951.3327519245 0.05093857936490095 0.9824450236251374 1.7866853058657565e-05 4.747951934322179 0.8851395753301483 IAS(ph)GEEVGNLNLAR ddPTM_PC-9_Lapatinib_30min_R1 1 IASGEEVGNLNLAR 14 0 Q8N437 Q8N437 RASGEF1B 1 IAS(1)GEEVGNLNLAR 55.776 0.041597 8745800.0 50891.0 36140.0 52926.0 34731.0 42896.0 41560.0 41302.0 31295.0 49596.0 31752.0 True False 50165.2850077336 36056.32005043496 48574.628580268116 37285.233599219624 40372.941616780816 39782.57568109183 43440.415467761944 32749.079948014376 44009.976210966786 37240.290893119476 1.3470701706307602 0.9682072611601628 1.3043568515530253 1.0012068301568624 1.084119931625994 1.0682670496658786 1.1664896923720862 0.8793991443838346 1.181783900058044 1.0 15.184576721737827 -4.7465920516995395 24.99684329244925 1.0770416148289943 1.347070882646674 0.3363870804933592 0.11548377901654995 921.2020611486057 1550841.9231746676 0.026771057358669886 0.5976066946102538 1.792288624213783e-05 4.7465920516995395 0.27002926781767966 IAS(ph)HDFDPTGLVQR ddPTM_PC-9_AZD4547_30min_R2 4 IASHDFDPTGLVQR 14 0 Q9NZN5-2 Q9NZN5-2 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 IAS(1)HDFDPTGLVQR;IAS(1)HDFDPTGLVQR;IAS(1)HDFDPTGLVQR;IAS(0.998)HDFDPT(0.002)GLVQR 82.94200000000001 0.0049023 28553300.0 66542.9 76276.0 95111.0 140520.0 125233.0 106174.0 87518.0 122694.0 94882.0 94418.5 True False 87702.15802169681 100930.72534152296 93849.76599557667 108125.28501235832 107846.5596289315 99534.92299569794 95306.93245516892 103734.46152763581 99897.26881455792 91112.93705375471 0.9625653706010421 1.1077540534334436 1.0300377644527834 1.1867171502611829 1.1836580305308817 1.0924345786040728 1.046030734350489 1.138526150972772 1.0964114652085097 1.0 16.47536829524718 -3.9720182345454695 1.5036950941501446 1.1067616977357764 1.0003051548647447e-11 0.30509724525644166 0.059179920917416876 13.728375310738956 4.584192688405405 0.016585807046377757 40.5190017790919 0.0001066551339433597 3.9720182345454695 -1.1067616977257733 IAS(ph)HDFDPTGLVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IASHDFDPTGLVQR 14 0 Q9NZN5-2 Q9NZN5-2 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 IAS(1)HDFDPTGLVQR;IAS(1)HDFDPTGLVQR;IAS(1)HDFDPTGLVQR 133.87 8.4853e-06 14859800.0 73591.0 71576.0 68747.0 82220.0 93179.0 65765.0 71930.0 71483.0 65137.4 58638.7 True False 86048.50281149663 78681.59225069525 70386.18920444931 77613.47996083635 74921.24384104823 62316.16762733415 65116.26967189722 69606.64699249915 66089.91124714616 69269.4321263062 1.2422290781104628 1.1358775412973918 1.0161219320537638 1.1204578640014773 1.081591714285119 0.8996200158492214 0.940043359286733 1.00486816270672 0.9540992212356745 1.0 16.079931226156994 -1.5228795658364473 0.3748903770683232 0.9591466800898835 4.871163290464953 0.7063297815378782 0.0538573319693637 38.8138071205764 0.5332144415634898 0.045128809702015965 109.81698242690858 0.029999943318045556 1.5228795658364473 3.912016610375069 IAS(ph)HDFDPTGLVQR ddPTM_PC-9_Lapatinib_30min_R1 4 IASHDFDPTGLVQR 14 0 Q9NZN5-2 Q9NZN5-2 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 IAS(1)HDFDPTGLVQR;IAS(0.997)HDFDPT(0.003)GLVQR;IAS(1)HDFDPTGLVQR;IAS(1)HDFDPTGLVQR 113.11 0.00013634 25220400.0 108182.0 95721.0 98479.0 77064.0 97321.0 96787.0 93922.0 81465.0 90635.0 90703.0 True False 106639.30484185096 95499.3639055809 90382.43675993323 82731.54363796764 91596.77012044784 92647.64563151679 98784.82159612456 85250.16130260404 80426.73187113824 106380.89269584944 1.0024291218042354 0.8977116236335824 0.8496115652868516 0.7776917596894305 0.8610265227076965 0.8709049462143829 0.9285955315167115 0.8013672299812367 0.7560261042467843 1.0 16.698879522941418 -4.810183878327334 2.407349681545524 0.8494643093362018 1.0320921163712649 0.2976321895332622 0.06764631874870741 0.6209488601708577 4.703805100269973 0.01747341662302626 0.23424242146261806 1.5481609957365093e-05 4.810183878327334 0.1826278070350631 IAS(ph)LDAANAR ddPTM_PC-9_AZD4547_30min_R2 2 IASLDAANAR 10 0 A0A3B3ITG3;Q5VWQ8-2;Q5VWQ8;H0Y3A3;Q5VWQ8-3;Q5VWQ8-4;Q5VWQ8-5 A0A3B3ITG3 DAB2IP Disabled homolog 2-interacting protein 1 IAS(1)LDAANAR;IAS(1)LDAANAR 93.839 0.012437 3468100.0 19583.4 27500.0 26335.0 36778.0 31878.0 30789.0 29745.0 33052.0 22825.0 25336.0 True False 25810.513839975403 36388.8372081898 25985.78069301668 28299.40031443574 27452.289954333726 28863.7589627832 32392.24737629968 27944.572859401535 24031.48290183896 24448.994351678215 1.055688159141144 1.4883572176739455 1.0628568324419847 1.157487294052781 1.1228392284547835 1.1805703967861545 1.324890787341371 1.1429743267736237 0.9829231646981588 1.0 14.577487504289955 -8.163547055501354 4.045015662781043 0.9910326278783932 1.2013614022398151 0.31016998563089015 0.12142062183900859 0.26844085685819863 7.491559015169722 0.09075064111148157 0.03063777664067066 6.862035247146717e-09 8.163547055501354 0.21032877436142194 IAS(ph)LDAANAR ddPTM_PC-9_Lapatinib_30min_R1 1 IASLDAANAR 10 0 A0A3B3ITG3;Q5VWQ8-2;Q5VWQ8;H0Y3A3;Q5VWQ8-3;Q5VWQ8-4;Q5VWQ8-5 A0A3B3ITG3 DAB2IP Disabled homolog 2-interacting protein 1 IAS(1)LDAANAR 109.39 0.0018908000000000002 1840400.0 14677.0 16528.0 12245.0 12134.0 15995.0 15138.0 15295.0 18717.0 14050.0 15193.0 True False 14467.703288567847 16489.7304314773 11238.263367066907 13026.374837837397 15054.205547379921 14490.583028401541 16086.90026099023 19586.660149767857 12467.541046940942 17819.089806600023 0.8119215653320938 0.9253968979588205 0.6306867235667873 0.7310348047638522 0.844835831165966 0.8132055669327378 0.9027902342706525 1.0991953215541426 0.6996732819834087 1.0 14.12113602589071 -7.238623387417613 3.0278271990988603 0.9367740531061094 0.7877697717361102 0.23775256268014167 0.11732264318300134 0.38329836180776927 7.128498108628887 0.05103590804750532 0.03553205175078676 5.772668421147781e-08 7.238623387417613 -0.14900428136999921 IAS(ph)PVSR ddPTM_PC-9_AZD4547_30min_R2 3 IASPVSR 7 0 A0A087WU64;A6NMQ1;P09884 A0A087WU64 POLA1 DNA polymerase;DNA polymerase alpha catalytic subunit 1 IAS(0.778)PVS(0.222)R;IAS(0.962)PVS(0.038)R;IAS(0.994)PVS(0.006)R 85.161 0.023932 8718800.0 38187.4 48623.3 41886.0 60068.0 44849.0 49454.6 47402.0 48271.4 38395.7 42803.2 True False 50330.19885273629 64339.83084454457 41330.56427217379 46220.25064134879 38622.4905000914 46362.19604406956 51620.686170158246 40812.16429642128 40425.21831562486 41304.6729962801 1.2185110110245645 1.557688904844714 1.0006268364815774 1.1190077850395135 0.9350634613078705 1.12244433089314 1.249754142220354 0.988076199031931 0.9787081069317642 1.0 15.334017389455285 -5.273824698340055 24.98992769376523 1.056978151881923 1.388099964068357 0.5758774457321698 0.11617908161052905 456.7499962068685 921587.3101979753 0.02984776248472809 0.06283207243889637 5.323230865177206e-06 5.273824698340055 0.3311218121864339 IAS(ph)PVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IASPVSR 7 0 A0A087WU64;A6NMQ1;P09884 A0A087WU64 POLA1 DNA polymerase;DNA polymerase alpha catalytic subunit 1 IAS(0.996)PVS(0.004)R;IAS(0.955)PVS(0.045)R;IAS(0.993)PVS(0.007)R;IAS(0.995)PVS(0.005)R 90.601 0.015819 93097700.0 54945.9 67933.0 68987.0 74656.0 87944.0 73633.0 70763.0 63150.0 62242.0 56982.0 True False 64247.155639007484 74676.93928644377 70631.9117146545 70473.2663580178 70712.0045112863 69771.55585651177 64059.81636024557 61492.37941295578 63152.17149970472 67312.38553073617 0.9544626168340292 1.1094085983974644 1.0493152360853795 1.0469583836965386 1.0505051032398458 1.036533697422634 0.9516794844686435 0.9135373665352737 0.9381954153276619 1.0 16.038584365807896 -7.259090026124334 4.126607923874563 0.9421956295224965 1.0462213728121086 0.5372839800792348 0.040780438498938115 0.14654701048014165 6.101740447061829 0.016305427347450826 0.011514833507789046 5.506935297625857e-08 7.259090026124334 0.10402574328961212 IAS(ph)PVSR ddPTM_PC-9_Lapatinib_30min_R1 5 IASPVSR 7 0 A0A087WU64;A6NMQ1;P09884 A0A087WU64 POLA1 DNA polymerase;DNA polymerase alpha catalytic subunit 1 IAS(0.975)PVS(0.025)R;IAS(0.777)PVS(0.223)R;IAS(0.984)PVS(0.016)R;IAS(0.978)PVS(0.022)R;IAS(0.967)PVS(0.033)R 89.698 0.016425 107924400.0 112661.0 108318.0 123273.0 102874.0 116787.0 97366.0 101069.0 103193.0 116787.0 91198.0 True False 111054.43348050264 108067.19632603817 113137.9697875411 110439.69713760368 109917.81827207636 93201.88315123167 106301.85828558497 107987.72350456781 103633.21823836969 106961.45278630336 1.0382659414918063 1.010337776001827 1.0577452609359907 1.0325186715465566 1.027639541243699 0.8713595479806943 0.9938333438492446 1.0095947716820453 0.9688837944770338 1.0 16.706731440281402 -6.561456542112145 24.999999811915472 0.9685245038994612 1.0340529822716373 0.4293483260493278 0.037286736374805785 159.7087060500041 103496.82194908269 0.012435569818362862 0.012435582866450712 2.745007010193088e-07 6.561456542112145 0.06552847837217612 IASLEVENQSLR ddPTM_PC-9_Lapatinib_30min_R1 2 IASLEVENQSLR 12 0 P29692-2;P29692;E9PRY8;A0A087X1X7;E9PK01;P29692-3;E9PI39;E9PQ49;E9PL71;E9PL12;E9PPR1;H0YCK7;E9PIZ1;E9PMW7;E9PN91 P29692-2 EEF1D Elongation factor 1-delta 0 ; 177.57 0.0041178000000000005 14791900.0 29098.0 30190.0 27996.0 29696.0 33180.0 31935.0 29318.0 27038.0 27575.0 30575.0 False True 28683.057184080324 30120.096909868058 25694.276947685168 31879.942902952007 31228.41763438987 30569.214494120984 30835.94258592427 28294.284187071808 24469.21312237699 35859.84801137335 0.7998655536683583 0.8399393355017882 0.7165194046426505 0.8890150034333922 0.8708463467130543 0.8524635822334109 0.8599016531287111 0.7890240967585238 0.6823568553502041 1.0 15.130081753040104 -5.782107368550405 24.997538728300647 0.8417940778981129 0.7908911309338049 0.11049162510970956 0.08047796304807774 648.6961955285892 784583.4406421944 0.022696930887222914 0.03370744069845256 1.6515534420840867e-06 5.782107368550405 -0.05090294696430797 IASPEGQDYLK ddPTM_PC-9_Lapatinib_30min_R1 1 IASPEGQDYLK 11 0 Q9Y3I0 Q9Y3I0 RTCB tRNA-splicing ligase RtcB homolog 0 88.134 0.046044999999999996 2477100.0 12032.0 14045.0 10118.0 11130.0 13608.0 13282.0 11336.0 10501.0 11206.0 10314.0 False True 11860.421473601436 14012.479665422232 9286.137096609464 11948.537328591587 12807.604194357356 12713.959821854236 11922.922612526001 10988.91479578524 9943.862275588628 12096.761157458875 0.9804625650799337 1.1583662339883534 0.7676548272496578 0.9877468169423272 1.0587630877096532 1.0510218112403413 0.9856293314656638 0.9084179354082281 0.8220268339725987 1.0 13.562333204937211 -7.751286697046136 4.489645538951131 0.8969495273092065 1.0005245533416742 0.13668607274317301 0.10096777454128493 0.36489176069101215 17.785392882123492 0.054502084814837905 0.027708655647567436 1.7730186462404964e-08 7.751286697046136 0.10357502603246771 IATGS(ph)FLK ddPTM_PC-9_AZD4547_30min_R2 1 IATGSFLK 8 0 E9PBS1;P22234;P22234-2;D6RF62 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 1 IAT(0.046)GS(0.954)FLK 95.775 0.0063234 5444200.0 34386.0 37193.0 42099.0 52021.0 47201.0 40640.0 36606.0 45040.0 39431.0 38839.0 True False 45320.032726768266 49214.90990124373 41540.739753002075 40028.36216643813 40647.95589856663 38098.77437550782 39863.8630847815 38080.10291623638 41515.24216001803 37479.25843167154 1.2092030265057472 1.313123897340911 1.1083661067823694 1.0680137185588627 1.0845453618745404 1.0165295678132407 1.0636246487495835 1.0160313866844575 1.1076857946830645 1.0 15.193804787521628 -5.422419258317182 3.8186686220384445 1.0535522254372103 1.2600566483479794 0.81224533048625 0.03972804380202874 0.08544578002241977 2.219962545782997 0.010105072887485323 0.022465202057012763 3.78077420878909e-06 5.422419258317182 0.2065044229107691 IATGS(ph)FLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IATGSFLK 8 0 E9PBS1;P22234;P22234-2;D6RF62 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 1 IAT(0.023)GS(0.977)FLK;IATGS(1)FLK 86.882 0.012143000000000001 11943200.0 93311.0 92884.0 96063.0 117748.0 108105.0 100104.0 108994.0 93859.0 89457.0 71969.0 True False 109106.70932374275 102104.90967102916 98353.50624095602 111150.96130416641 86922.60128823596 94854.37001697946 98669.2992717749 91395.30070183093 90765.1393889831 85016.40999370946 1.2833605809962545 1.2010023674086463 1.156876728248504 1.307405962124144 1.0224214512782597 1.1157183657131362 1.160591223260023 1.075031287590166 1.0676190560822199 1.0 16.37545371881795 -1.5228787452803436 0.13155129033401325 0.9564695105755202 2.006165221741483 0.5835253229816042 0.06338604384827379 60.69433681940146 0.5410625675930164 0.3302670570636651 11.835777257653174 0.029999999999999583 1.5228787452803436 1.0496957111659628 IATGS(ph)FLK ddPTM_PC-9_Lapatinib_30min_R1 1 IATGSFLK 8 0 E9PBS1;P22234;P22234-2;D6RF62 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 1 IAT(0.003)GS(0.997)FLK 88.49600000000001 0.010931999999999999 5713800.0 48829.0 48337.0 48855.0 45084.0 50408.0 45728.0 42791.0 35066.0 41178.0 30033.0 True False 48132.68950585806 48225.078646316404 44838.33048575367 48399.62775581517 47443.10054594105 43772.320037174395 45006.50860202895 36695.2943747267 36540.10001643663 35224.16403354296 1.3664679014105965 1.3690907923433766 1.2729423597691463 1.3740461721029231 1.3468907452498333 1.2426787473363816 1.2777168695663166 1.0417648049725985 1.0373588988979423 1.0 15.104277847362624 -7.695513336653174 1.3574240636448125 0.9955422680509517 1.3399506823991219 0.9091487805202174 0.04284165379408677 0.11765580103252861 0.40309050420345466 0.033263607612303715 0.0135277011367649 2.0159820613666234e-08 7.695513336653174 0.34440841434817016 IATQSQIT(ph)PPGTPSSALSSGEQR ddPTM_PC-9_AZD4547_30min_R2 1 IATQSQITPPGTPSSALSSGEQR 23 0 Q8N0Z3;H7C5N4 Q8N0Z3 SPICE1 Spindle and centriole-associated protein 1 1 IAT(0.002)QS(0.1)QIT(0.898)PPGTPSSALSSGEQR 90.758 4.0223000000000004e-05 5101000.0 12158.0 10138.0 17743.0 20126.0 16206.0 11623.0 16013.0 11900.0 11894.0 14174.0 True False 16023.991097890077 13414.910240604657 17507.716226929737 15486.261643600354 13956.07663592234 10896.211972601557 17438.12597870859 10061.128434796026 12522.692557917742 13677.772574229839 1.171535131976147 0.9807817879557057 1.280012233857131 1.1322210220674287 1.02034717715784 0.7966364342927449 1.2749243989890282 0.7355823749951876 0.9155505759403858 1.0 13.73954568596059 -6.395944511673143 3.8976323155755415 0.9454695579577993 1.1390910805086527 0.2735938321199952 0.15021296487253688 0.33127265787391935 8.758559727513173 0.047480202695570586 0.05398690859376333 4.018421495720625e-07 6.395944511673143 0.1936215225508534 IATS(ph)LDGFDVASVQQQR ddPTM_PC-9_AZD4547_30min_R2 1 IATSLDGFDVASVQQQR 17 0 O60664-3;O60664;K7ERZ3;O60664-4;O60664-2 O60664-3 PLIN3 Perilipin-3 1 IAT(0.003)S(0.993)LDGFDVAS(0.004)VQQQR 119.56 0.00087299 0.0 7285.2 5199.6 10221.0 12841.0 11545.0 12810.0 7327.3 13101.0 7986.2 8462.2 True False 9601.74205842646 6880.269016280128 10085.462861717238 9880.705841472323 9942.176031205938 12008.988674957052 7979.415505139034 11076.541481030486 8408.334227849562 8165.940953693217 1.1758280047425365 0.8425567923275741 1.2350643874244374 1.20998987103912 1.2175175019737783 1.470619092527939 0.9771581193628613 1.3564317380988273 1.0296834468349563 1.0 12.995403420419866 -4.430054420954524 22.3560225007719 1.1618302905749924 2.8409606872840247 0.0 0.17991528563225506 16152.055501123972 4947283.517529674 0.042603296445025175 376245.3929478673 3.7148867535110146e-05 4.430054420954524 1.6791303967090323 IATTTASAATAAAIGAT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 IATTTASAATAAAIGATPR 19 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 IATTTASAATAAAIGAT(1)PR;IATTTASAATAAAIGAT(1)PR 198.67 1.3059e-14 12661100.0 14918.9 19429.5 19560.3 24847.1 22369.0 27908.0 18884.9 29887.0 19250.2 22944.2 True False 19662.79986760261 25709.705910419052 19300.917641527027 19118.98497886823 19263.45046704596 26162.90834822026 20565.619515101098 25268.650884936887 20267.7262719378 22140.930541670958 0.8880746827959958 1.161184524834283 0.8717301924235386 0.863513163680488 0.8700379792434941 1.1816535126642318 0.9288507308396545 1.1412641775547472 0.9153963169611304 1.0 14.434428236702452 -6.723234424878906 24.999997458300207 1.0357262834323615 0.9366694623492224 0.17108428762742445 0.11242257837194225 315.3653756609162 206363.2826721393 0.03666743048970706 0.03666669565200772 1.891322438923853e-07 6.723234424878906 -0.09905682108313907 IATTTASAATAAAIGAT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IATTTASAATAAAIGATPR 19 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 IATTTASAATAAAIGAT(1)PR;IATTTASAATAAAIGAT(1)PR 229.93 3.5287e-35 13509400.0 25103.0 28910.0 23405.0 22597.4 22059.0 23301.0 13938.5 20255.8 19902.3 17446.5 True False 29352.442093149886 31779.993740466107 23963.063963956796 21331.340939759277 17736.697301856457 22079.054540933827 12618.144373998879 19724.106712794142 20193.333486047584 20609.412343581997 1.4242250872471174 1.5420135814965512 1.1627242720202629 1.035029072354996 0.8606115014909614 1.0713092723291304 0.6122515365135247 0.9570436256973844 0.9798112216594093 1.0 14.331015748032291 -5.5526215987807435 1.7350485921029002 0.9056739200020198 1.5021495204796647 0.7594728432952356 0.12377675245612345 0.17242923599948337 1.0104939381618825 0.03687010175709524 0.10145887821353253 2.8014211376292865e-06 5.5526215987807435 0.5964756004776448 IATTTASAATAAAIGAT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 IATTTASAATAAAIGATPR 19 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 IATTTASAATAAAIGAT(1)PR;IATTTASAATAAAIGAT(1)PR 197.94 1.5244e-14 12853200.0 41739.0 34345.0 30591.0 25040.0 31226.0 25110.0 21714.0 25533.0 28864.0 20225.7 True False 41143.794206004844 34265.47626265051 28075.926064674877 26881.525130991293 29389.348072678047 24036.103834268928 22838.244672582026 26719.3563927992 25613.03236860522 23721.685295948802 1.7344380760768037 1.4444790003390855 1.1835552876788942 1.1332046941699427 1.2389232765724774 1.0132544772598355 0.9627581003480536 1.1263683865396503 1.0797307210284686 1.0 14.533918888663468 -1.5228802233571705 0.557360332675769 1.0464008011231711 34.62105862371014 0.9100018591903042 0.06721479514182611 38.8652099104803 0.34767465286963367 0.03450436545849924 1566.5426128265126 0.02999989789824329 1.5228802233571705 33.57465782258697 IAVAAQNCYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IAVAAQNCYK 10 0 P60174;P60174-3 P60174 TPI1 Triosephosphate isomerase 0 ; 159.04 0.00051702 12281600.0 51202.0 77048.0 54576.0 62925.0 75832.0 66775.0 69475.0 58167.0 57699.0 58055.0 False True 59869.48731440312 84696.81624750706 55877.298820632604 59399.51625560249 60973.26396456688 63273.20144933082 62893.82504455805 56640.17788303086 58542.738719216315 68579.91193687287 0.8729886875549271 1.2350091135356025 0.8147764737882297 0.8661357907586577 0.8890834391956083 0.9226200451755199 0.9170881569875912 0.8259004172412409 0.8536426639495298 1.0 16.06549843126659 -5.289114249789774 24.998034953322716 0.8817345979840412 1.0539990395821421 0.3301733025633118 0.09545939532678602 642.05690335262 579953.2892189161 0.02305494593019461 0.048008238351168867 5.139084399753542e-06 5.289114249789774 0.17226444159810095 IAVAAQNCYK ddPTM_PC-9_Lapatinib_30min_R1 2 IAVAAQNCYK 10 0 P60174;P60174-3 P60174 TPI1 Triosephosphate isomerase 0 ; 215.1 6.1239e-07 40345000.0 186061.0 176343.0 172258.0 164817.0 161851.0 157055.0 186033.0 144791.0 164969.0 156699.0 False True 183407.73602059166 175934.6886179815 158095.61217510907 176938.19199339423 152331.24239130906 150338.12376308654 195664.87847354036 151518.5184455325 146388.4540194166 183784.2133617076 0.9979515251379345 0.9572894504911726 0.8602241143746088 0.9627496766828408 0.8288592344517881 0.8180143496177472 1.0646446443604505 0.8244370703773526 0.7965235497746913 1.0 17.487653322223053 -5.060631933056781 4.025166110612671 0.8917604684852305 0.9918873133017028 0.14195548671131875 0.08412507321168725 0.39620879444572155 12.600902003584679 0.02148748223544102 0.07272826774163334 8.696971901520887e-06 5.060631933056781 0.10012684481647227 IAVHCTVR ddPTM_PC-9_AZD4547_30min_R2 1 IAVHCTVR 8 0 Q5VVC8;P62913-2;P62913 Q5VVC8 RPL11 60S ribosomal protein L11 0 93.162 0.0062369999999999995 2941300.0 7680.0 10058.0 26769.0 41535.0 33331.0 21547.0 16433.0 36926.0 15701.0 31036.0 False True 10122.080246076313 13309.05180508992 26414.025569446112 31959.747459353115 28703.565984939367 20199.662683786082 17895.505165060775 31219.935175065406 16530.922805773214 29949.43908662317 0.3379722811101765 0.44438400888230223 0.8819539321938039 1.0671234064489656 0.9584007868033739 0.674458797888078 0.5975238839465862 1.0424213650468566 0.5519610152951647 1.0 14.870241363046818 -5.199340811343535 4.567439684663137 0.8453733396904698 0.3697363259709757 0.5226740415522377 0.17484338679422448 0.17061884085708368 7.220989970898348 0.04603809265574216 0.1299292504744787 6.31915762675286e-06 5.199340811343535 -0.4756370137194941 IAVHCTVR ddPTM_PC-9_Lapatinib_30min_R1 1 IAVHCTVR 8 0 Q5VVC8;P62913-2;P62913 Q5VVC8 RPL11 60S ribosomal protein L11 0 107.29 0.0031997 3504800.0 30735.0 35251.0 62007.0 40585.0 49076.0 61962.0 40184.0 36320.0 64307.0 37177.0 False True 30296.713263891303 35169.378475315 56909.02381394182 43569.756287591146 46189.44616712832 59312.02970047674 42264.530898177916 38007.559792678774 57064.06847726916 43602.99491476134 0.6948310161519357 0.806581716326297 1.3051631871891411 0.9992376985288473 1.0593182018213012 1.3602742154850762 0.9693033925949363 0.8716731469244035 1.3087190131967452 1.0 15.412139610888422 -5.091489511125504 5.877695848449478 1.1022064206491806 0.72031503388932 0.4617433015087581 0.15660284580496933 0.17786885096484498 8.997647755338832 0.03947175786507038 0.11021803149704901 8.10047505327536e-06 5.091489511125504 -0.38189138675986056 IAVYSCPFDGMITETK ddPTM_PC-9_Lapatinib_30min_R1 1 IAVYSCPFDGMITETK 16 0 P50990-2;P50990;P50990-3 P50990-2 CCT8 T-complex protein 1 subunit theta 0 89.959 0.016717 2082200.0 9686.7 5692.9 10299.0 7514.9 9248.5 8296.2 6594.0 8701.4 9384.3 8413.8 False True 9548.565881676781 5679.718439820736 9452.255975289669 8067.570814971512 8704.521413250595 7941.390865386769 6935.405055310208 9105.698810022439 8327.341312940065 9868.11411931622 0.9676181047588471 0.5755627033845343 0.957858397359579 0.8175392701610273 0.8820856050105902 0.8047526375725621 0.7028095714595136 0.9227395123247105 0.8438634993731793 1.0 13.268558684371829 -8.801476309635385 1.147941043689886 0.9986018998254411 0.8182198659090496 0.17068982503182162 0.11313672002932486 1.626348720460837 3.8706228148834776 0.10214790185766247 0.031701255726216244 1.5795147664666004e-09 8.801476309635385 -0.18038203391639152 ICDDELILIK ddPTM_PC-9_Lapatinib_30min_R1 1 ICDDELILIK 10 0 P17987;F5H282;E7EQR6;E7ERF2;F5GZ03 P17987 TCP1 T-complex protein 1 subunit alpha 0 131.44 0.00082806 3437100.0 20240.0 19300.0 21800.0 20006.0 23386.0 17076.0 22960.0 18795.0 18266.0 20166.0 False True 19951.37388843858 19255.312035788465 20007.688150433518 21477.30797805958 22010.481458645012 16345.6992861002 24148.75645585718 19668.284314520864 16208.690730492775 23651.66623049405 0.843550458306202 0.8141207409295598 0.8459314432840103 0.9080674388330799 0.9306101838299636 0.6911013848582778 1.02101713344501 0.8315813407328817 0.685308619381536 1.0 14.529654202767151 -7.079696118744231 0.009522266110158117 1.714115767986002 3.921942768788135e-06 0.05183580067948912 0.10449666884202441 10088.99443773945 48.531371992496965 4283.186565101155 4448.142148878255 8.323459702306522e-08 7.079696118744231 -1.7141118460432332 ICDECNYGSYQGR ddPTM_PC-9_AZD4547_30min_R2 1 ICDECNYGSYQGR 13 0 Q7RTV0 Q7RTV0 PHF5A PHD finger-like domain-containing protein 5A 0 97.95700000000001 0.015163999999999999 0.0 2318.9 1417.5 13688.0 32083.0 15916.0 11802.0 8094.4 22134.0 7195.8 15275.0 False True 3056.2619638836413 1875.6791542766923 13506.488176419682 24686.76002740881 13706.338130157968 11064.0190743047 8814.785919069427 18713.69888872062 7576.155297483145 14740.226899348145 0.20734158196837513 0.12724900146276855 0.9163012393667412 1.6747883323628165 0.9298593721623174 0.7506003231737215 0.59800883522758 1.2695665417164097 0.5139782005538995 1.0 13.847471111855219 -5.27696567180394 7.134221745105654 0.9719522731133244 0.16520445966838873 0.5015861599054586 0.31454027606577 0.11842514711377283 34.45551062627942 0.08472044931017078 0.18944978447112043 5.284870236372064e-06 5.27696567180394 -0.8067478134449357 ICDECNYGSYQGR ddPTM_PC-9_Lapatinib_30min_R1 1 ICDECNYGSYQGR 13 0 Q7RTV0 Q7RTV0 PHF5A PHD finger-like domain-containing protein 5A 0 124.39 0.0016538 0.0 8444.2 7771.7 11389.0 5911.3 7483.8 7626.1 7142.2 4919.8 9232.9 5785.5 False True 8323.784159523379 7753.705106141825 10452.640382811345 6346.036721518729 7043.617597716903 7299.949480307376 7511.988168947009 5148.3918686129155 8192.993575252747 6785.515966305827 1.2266987802926086 1.142684674922827 1.5404341298016244 0.9352327447213481 1.038037141566346 1.075813470420823 1.107062190443373 0.7587325553690805 1.2074238150696122 1.0 12.728242806087911 -5.787659030495992 24.9999860513726 1.0144395888108257 1.2872140292798133 0.4475705188020872 0.14515001311139747 194.63104727316266 185576.60502996534 0.03949744619830679 0.05860450022151587 1.6305757136415313e-06 5.787659030495992 0.2727744404689876 ICDQISDAVLDAHLQQDPDAK ddPTM_PC-9_Lapatinib_30min_R1 1 ICDQISDAVLDAHLQQDPDAK 21 0 P31153 P31153 MAT2A S-adenosylmethionine synthase isoform type-2 0 116.98 2.4988e-06 3441300.0 10143.0 11027.0 12003.0 11050.0 13467.0 9776.4 13519.0 12261.0 8641.3 13194.0 False True 9998.35896000161 11001.467658996857 11016.159672919888 11862.653861719413 12674.89753714069 9358.286161901495 14218.947671024966 12830.690820981123 7668.025797076925 15474.5653201001 0.6461156583839301 0.7109387198557957 0.711888149685915 0.7665904415622498 0.819079390920087 0.6047527648318434 0.918859262079291 0.8291470910859888 0.4955244711860716 1.0 13.917611264314118 -11.775070853537484 2.4001877853105955 2.0823433087626335 0.7314689329503761 0.3395252702155812 0.11549118403425734 23311475.579970792 4903904.587873063 136393152.84146574 0.028816928006904097 1.6785301498008375e-12 11.775070853537484 -1.3508743758122574 ICDQWDALGSLTHSR ddPTM_PC-9_AZD4547_30min_R2 2 ICDQWDALGSLTHSR 15 0 O43707;O43707-2;F5GXS2;O43707-3 O43707 ACTN4 Alpha-actinin-4 0 ; 182.7 3.4726e-06 16950800.0 36464.0 40967.0 91134.0 152686.0 119887.0 108945.0 65438.0 120657.0 76712.0 110002.0 False True 48058.79350168317 54208.78159665134 89925.50361410227 117486.60167518441 103242.75945025448 102132.65192765 71261.85522979662 102012.23307203208 80766.83970934807 106150.86346200315 0.45274048589238164 0.510676784236008 0.8471481124248342 1.1067889402259916 0.97260404751404 0.9621462190386094 0.6713261946786226 0.9610118066401551 0.7608684194854305 1.0 16.69575658102898 -5.274985223578884 3.8287254682802203 0.9152913440109267 0.46737212586459953 0.6874452943823339 0.11656468528829117 0.12142663516581828 4.04915087460498 0.032005809332929014 0.0826625593324723 5.309025073330811e-06 5.274985223578884 -0.4479192181463272 ICDQWDALGSLTHSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ICDQWDALGSLTHSR 15 0 O43707;O43707-2;F5GXS2;O43707-3 O43707 ACTN4 Alpha-actinin-4 0 ; 132.15 6.285499999999999e-06 10564500.0 56554.0 64446.0 105350.0 112885.0 138872.0 107920.0 108372.0 102906.0 102164.0 76812.0 False True 66127.47520758469 70843.77297122369 107861.94354209973 106560.419428108 111661.02850099323 102260.48521769777 98106.21961466491 100204.82653791973 103657.95522470096 90737.40755654236 0.7287785378525151 0.7807559735170735 1.1887263086603652 1.174382454796338 1.2305953135305576 1.1269936839883252 1.0812102996609279 1.1043386541044586 1.1423949395965194 1.0 16.469409820825625 -5.236439327344779 7.732841442852851 1.1380308812695386 0.7525015484805566 0.8583495132898542 0.06110099633520202 0.07590273882445556 19.370225496539312 0.015879623284922876 0.04082464510717402 5.801772199114235e-06 5.236439327344779 -0.38552933278898194 ICDQWDALGSLTHSR ddPTM_PC-9_Lapatinib_30min_R1 2 ICDQWDALGSLTHSR 15 0 O43707;O43707-2;F5GXS2;O43707-3 O43707 ACTN4 Alpha-actinin-4 0 ; 107.73 0.0006781000000000001 17420900.0 66627.0 64261.0 114372.0 80642.0 111275.0 131302.0 90697.0 94272.0 118205.0 74388.0 False True 65676.88676210471 64112.207602684066 104968.77564868718 86572.68169382578 104730.02327506719 125686.51953991165 95392.8468761708 98652.22127685591 104891.50814616766 87245.86668422043 0.7527793494196929 0.7348452143266933 1.2031375197247274 0.9922840471878034 1.200400973196006 1.4406014212091462 1.0933795548325256 1.130738051281213 1.2022518903481612 1.0 16.412799164104655 -5.25910684511329 24.958823614958305 1.1659208780466672 0.7438122339816009 0.6558020669247633 0.11986813074545227 113.75649888947957 1217209.6227918952 0.03168843348064825 0.0759412021421759 5.506722033828237e-06 5.25910684511329 -0.4221086440650663 ICDQWDNLGALTQK ddPTM_PC-9_Lapatinib_30min_R1 1 ICDQWDNLGALTQK 14 0 P12814-4;P12814-3;P12814;P12814-2;H9KV75;H7C5W8 P12814-4 ACTN1 Alpha-actinin-1 0 170.95 0.001127 3589100.0 23107.0 22719.0 22288.0 23767.0 20181.0 21016.0 20362.0 17524.0 22919.0 14714.0 False True 22777.489942695167 22666.395551351194 20455.566674168007 25514.904464387786 18993.993257372582 20117.1946706888 21416.244727968813 18338.229014507244 20337.620872230582 17257.29529482741 1.3198760033689836 1.313438471331314 1.1853286580950624 1.4784996158717558 1.1006355823942886 1.165721182085735 1.2409965966328442 1.0626363344436613 1.1784941107385727 1.0 14.074918750757776 -7.294718685602099 0.2587969293672348 0.9765461869536005 1.3902481630132284 0.48233936372448827 0.09568572948310591 2.0828594575882753 0.4257475975705254 0.19511669406832127 0.3147545358252059 5.07319218062562e-08 7.294718685602099 0.4137019760596279 ICNGGLS(ph)PGNPGDSK ddPTM_PC-9_AZD4547_30min_R2 1 ICNGGLSPGNPGDSK 15 0 Q9H792;H0YN99;H3BUZ5 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 ICNGGLS(0.99)PGNPGDS(0.01)K 88.319 0.0048858 7388800.0 19507.0 21885.0 24897.0 21734.0 23882.0 26384.0 23084.0 33840.0 24514.0 24034.0 True False 25709.82022919412 28958.898265499392 24566.849512589175 16723.56208695269 20566.39653332701 24734.204309138735 25138.431280366505 28610.80556584012 25809.759993677108 23192.576975380252 1.1085365915346972 1.2486278819399972 1.0592548442834862 0.7210739067377182 0.8867663371413609 1.0664707218777358 1.083899874819941 1.2336190840807173 1.1128457187433327 1.0 14.501375509281027 -9.362275985849378 12.441130128917345 0.9999971318958758 1.0547940451282836 0.0133594467788265 0.14711017749003952 0.0 0.0 0.1610173180424856 0.03905243587310826 4.3423418893895135e-10 9.362275985849378 0.05479691323240776 ICNGGLS(ph)PGNPGDSK ddPTM_PC-9_Lapatinib_30min_R1 2 ICNGGLSPGNPGDSK 15 0 Q9H792;H0YN99;H3BUZ5 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 ICNGGLS(0.995)PGNPGDS(0.005)K;ICNGGLS(0.995)PGNPGDS(0.005)K 170.79 8.3346e-21 7221300.0 43051.0 61820.0 57714.0 66648.0 64285.0 62343.0 57539.0 52342.0 59922.0 46045.0 True False 42437.08484541352 61676.85958820952 52968.977702482574 71549.51625121041 60503.88268917274 59676.73521863112 60518.08787951076 54774.00040386545 53172.95335336621 54003.81689889407 0.785816397475464 1.1420833402142838 0.9808376656348399 1.324897393552115 1.1203630810475507 1.1050466179151353 1.1206261215353113 1.014261649438841 0.9846147255279493 1.0 15.720773757686706 -10.71380760061478 14.519257053900253 0.9999637342455461 1.074816377834192 0.015195885483268667 0.13278119685267264 0.0 0.0 0.12686787987581014 0.03076998054271403 1.9328243994235262e-11 10.71380760061478 0.07485264358864585 ICNGGLSPGNPGDS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 ICNGGLSPGNPGDSK 15 0 Q9H792;H0YN99;H3BUZ5 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 ICNGGLS(0.003)PGNPGDS(0.997)K 154.24 1.7006e-10 0.0 13631.0 17125.0 16938.0 18122.0 16600.0 23196.0 18430.0 25576.0 17258.0 18465.0 True False 17965.37445758676 22660.32135237274 16713.3910529074 13944.252882108993 14295.376536857386 21745.550453107244 20070.234296359158 21623.81687801204 18170.222647094713 17818.545970308576 1.0082402058800335 1.2717267385415238 0.9379772670989698 0.7825696274737904 0.8022751441491397 1.2203886046225274 1.126367680606634 1.213556757888341 1.0197365529921545 1.0 14.12109199435474 -6.778428152875042 24.999664448521685 1.1300045605790625 0.9667022044033177 0.22786590401279483 0.14168816342175888 402.8257230689088 592770.4969570481 0.054817566244002025 0.048465461513843656 1.6656043527823195e-07 6.778428152875042 -0.16330235617574484 ICRDPQT(ph)PVLQTK ddPTM_PC-9_AZD4547_30min_R2 2 ICRDPQTPVLQTK 13 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 ICRDPQT(0.986)PVLQT(0.014)K;ICRDPQT(0.999)PVLQT(0.001)K 90.714 0.0039454 118959000.0 170886.0 162651.0 173540.0 248051.0 227610.0 218596.0 153737.0 234579.0 168403.0 207388.0 True False 225224.19335038998 215224.75493633744 171238.74621097837 190866.67429974698 196010.28033458494 204927.15756369338 167419.29517196768 198330.20563916132 177304.43877846163 200127.4092439942 1.1254040323671903 1.075438670541808 0.8556486433210408 0.9537258040803568 0.9794274611110881 1.0239834630240348 0.8365635462149567 0.9910197028401955 0.8859577978261493 1.0 17.61055924524051 -5.096069099197085 5.6833826538323216 0.9418976250858769 1.1140448300671122 0.5372041787732417 0.05998465139592636 0.14849632918759295 6.912648451863723 0.01483255936900935 0.0416467128628736 8.01550521118187e-06 5.096069099197085 0.17214720498123526 ICRDPQT(ph)PVLQTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ICRDPQTPVLQTK 13 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 ICRDPQT(0.998)PVLQT(0.002)K;ICRDPQT(0.995)PVLQT(0.005)K;ICRDPQT(0.999)PVLQT(0.001)K;ICRDPQT(0.999)PVLQT(0.001)K 76.051 0.012739 95533000.0 205285.0 181079.0 230166.0 226254.0 253153.0 215438.0 191213.0 173799.0 166881.0 150324.0 True False 240035.69593643356 199055.32641058025 235654.03034941628 213577.72190536498 203549.48692401563 204140.0520230762 173099.9203777626 169236.960405262 169321.3189171659 177576.5512358704 1.3517308128008425 1.1209550192591595 1.327056014486975 1.202736061822009 1.1462633185934896 1.149589011625314 0.9747904167135131 0.9530366437878889 0.9535116981310258 1.0 17.4380815626046 -6.975431707604826 1.164917353279723 0.9530494065474665 1.2481748792988256 0.7847962115152777 0.0649497995421177 0.2062190228902123 0.5767237832009281 0.03568335795842723 0.02626106338814199 1.0582013040646348e-07 6.975431707604826 0.29512547275135914 ICRDPQT(ph)PVLQTK ddPTM_PC-9_Lapatinib_30min_R1 2 ICRDPQTPVLQTK 13 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 ICRDPQT(1)PVLQTK;ICRDPQT(0.994)PVLQT(0.006)K 84.375 0.0062126 132407000.0 191298.0 158352.0 182817.0 156289.0 142277.0 141741.0 109791.0 91039.0 129639.0 89814.0 True False 188570.05544024296 157985.34567311793 167786.49195402773 167783.01442482002 133908.54658734438 135679.06784440912 115475.44076851106 95269.00429420928 115037.69066080979 105338.23023036758 1.7901388226084016 1.4997911520595577 1.5928356835603752 1.5928026705773386 1.2712245715016803 1.2880325362186946 1.0962348666383903 0.9044105267941412 1.0920792043803105 1.0 16.684669600771713 -6.658843938828071 0.8381535108920342 0.9802603512057279 1.6604374033310565 0.8935481104714385 0.09125205147870351 0.18008960321321696 0.2786550897259114 0.055729634927183865 0.05879736314448157 2.193593048521427e-07 6.658843938828071 0.6801770521253286 ICT(ph)LPEK ddPTM_PC-9_AZD4547_30min_R2 2 ICTLPEK 7 0 Q658Y4;E7ER68;G3V120 Q658Y4 FAM91A1 Protein FAM91A1 1 ICT(1)LPEK;ICT(1)LPEK 111.28 0.02284 8557300.0 35270.0 32263.0 41542.0 74649.0 69625.0 58321.0 45658.0 55491.0 48877.0 59319.0 True False 46485.126338426 42691.38381264828 40991.12593693938 57439.82636555314 59958.77056498167 54674.1786504427 49721.473548733964 46916.14100632491 51460.53843562685 57242.25986529836 0.8120770641797531 0.745801858855835 0.7160990155419981 1.0034514098625682 1.0474563846024907 0.9551366207256872 0.8686147902919592 0.8196067226683098 0.8989955769867057 1.0 15.80479300884851 -5.7562717346954075 24.998661886041802 0.9362749633096337 0.756773539613969 0.6076965704757483 0.06760404664687342 100.24493263991043 484931.19353747036 0.021240763138552658 0.03541294678707511 1.7527834556311835e-06 5.7562717346954075 -0.17950142369566469 ICT(ph)LPEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ICTLPEK 7 0 Q658Y4;E7ER68;G3V120 Q658Y4 FAM91A1 Protein FAM91A1 1 ICT(1)LPEK;ICT(1)LPEK;ICT(1)LPEK 104.11 0.0047748999999999995 0.0 59196.0 51906.0 61047.0 67881.0 73612.0 68327.0 68381.0 71600.0 59694.0 57751.0 True False 69216.71362570612 57058.884645196624 62502.59200203677 64077.847643171255 59188.25702816346 64743.81183719086 61903.45664443215 69720.57586647097 60566.91182004711 68220.79914333565 1.0145983995332273 0.8363854625231342 0.9161808830576051 0.9392714311150206 0.867598412381621 0.9490333248832302 0.9073985855013159 1.0219841564738081 0.8878071289196232 1.0 16.057924034432965 -7.700683660170379 24.999996341778825 0.9661740827544233 0.9153794818970697 0.15046304309525937 0.05525901591094416 122.29373608587244 50321.17176583525 0.024202790148273656 0.013973477304725984 1.992123872424826e-08 7.700683660170379 -0.050794600857353545 ICT(ph)LPEK ddPTM_PC-9_Lapatinib_30min_R1 4 ICTLPEK 7 0 Q658Y4;E7ER68;G3V120 Q658Y4 FAM91A1 Protein FAM91A1 1 ICT(1)LPEK;ICT(1)LPEK;ICT(1)LPEK;ICT(1)LPEK 118.01 0.0073201 13673700.0 126360.0 118514.0 123724.0 109851.0 124801.0 120075.0 93173.0 102338.0 130670.0 90557.0 True False 124558.08322841409 118239.5881144784 113551.89030845108 117929.80899219376 117460.4505482065 114939.67215849625 97997.0420410097 107092.99708323668 115952.56858389846 106209.65679038239 1.1727566682024455 1.113265890199029 1.0691296228605605 1.1103492145252152 1.1059300453256233 1.082196060433032 0.9226754421626531 1.0083169489437074 1.0917328243772118 1.0 16.696555419206213 -7.035521921620502 12.426475933422545 1.005790750782072 1.1097667290281366 0.5686889071865284 0.04469959478262002 1.326426504598839 462.8656936933526 0.017419625247306676 0.013585077181931055 9.214633754102821e-08 7.035521921620502 0.10397597824606453 ICTEQSNS(ph)PPPIR ddPTM_PC-9_AZD4547_30min_R2 4 ICTEQSNSPPPIR 13 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 ICTEQSNS(1)PPPIR;ICTEQSNS(1)PPPIR;ICTEQSNS(1)PPPIR;ICTEQSNS(1)PPPIR 193.51 1.4300999999999999e-06 63576000.0 61377.0 60005.0 85841.0 97528.0 99840.0 84288.0 75698.0 96389.0 80620.0 83037.0 True False 80893.60927909202 79400.4427882702 84702.69225248697 75044.4263925795 85978.93936384578 79017.45803550218 82434.97535354304 81494.29484887005 84881.40861100802 80129.89990449561 1.0095308914089078 0.9908965677344558 1.0570672414846585 0.9365346329150873 1.072994468560693 0.9861170191112266 1.0287667331644588 1.0170272887648757 1.0592975744656563 1.0 16.29005305407992 -6.932167226079705 0.9475193263672204 1.0275132171782915 1.0065019968840354 0.03816512690161977 0.03812142356044457 2.0681575658222844 3.901128467956617 0.023354153682616136 0.018043380718997932 1.169049159301839e-07 6.932167226079705 -0.02101122029425606 ICTEQSNS(ph)PPPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ICTEQSNSPPPIR 13 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 ICTEQSNS(1)PPPIR;ICTEQS(0.172)NS(0.828)PPPIR;ICT(0.002)EQS(0.053)NS(0.945)PPPIR;ICTEQS(0.001)NS(0.999)PPPIR 193.11 1.4894999999999999e-06 47944600.0 48622.7 54895.5 64527.0 63086.0 61461.0 48636.2 54124.2 60898.0 50865.9 42894.0 True False 56853.56276790022 60345.1624482794 66065.56840001022 59551.49594757154 49418.158251480134 46085.632052863184 48997.16395072571 59299.49202676453 51609.71755867147 50670.34265128281 1.1220283857003062 1.1909365378398848 1.3038310961241872 1.175273203842522 0.9752876271546 0.9095188554383389 0.9669791319140658 1.17029980307945 1.0185389491808554 1.0 15.62885396447138 -6.1882959984635 5.236778894566042 1.0086043541353702 1.2083168963796005 0.609685306544619 0.07504240416384687 0.1643253280979012 8.345508596505297 0.024572049967876868 0.03184592282676476 6.481924998133687e-07 6.1882959984635 0.1997125422442303 ICTEQSNS(ph)PPPIR ddPTM_PC-9_Lapatinib_30min_R1 2 ICTEQSNSPPPIR 13 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 ICTEQS(0.191)NS(0.809)PPPIR;ICTEQS(0.208)NS(0.791)PPPIR 168.93 0.00026072 29199000.0 95795.0 78471.0 97855.0 83955.0 90549.0 84101.0 79497.0 79768.0 99138.0 73895.0 True False 94428.94573334848 78289.30522074374 89809.73963122358 90129.33076566989 85223.08584618355 80504.1962790063 83612.96567819163 83474.31248740069 87972.03447057879 86667.65229110174 1.089552367429752 0.9033278639853244 1.0362544416175958 1.0399419896934667 0.9833321151925734 0.9288840086334236 0.9647540168429861 0.9631541905280281 1.0150503924474135 1.0 16.40320600405476 -6.510317712365936 24.150302586840933 0.9697584556520578 1.010630405246475 0.13994418108349105 0.04895259277079798 800.3243689808178 1538737.3608696968 0.015193640901068733 0.016391487524159257 3.0880355234659183e-07 6.510317712365936 0.0408719495944172 ICTEQSNS(ph)PPPIRR ddPTM_PC-9_Lapatinib_30min_R1 4 ICTEQSNSPPPIRR 14 1 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 ICT(0.006)EQS(0.286)NS(0.708)PPPIRR;ICT(0.001)EQS(0.027)NS(0.972)PPPIRR;ICT(0.002)EQS(0.133)NS(0.865)PPPIRR;ICTEQS(0.004)NS(0.996)PPPIRR 95.98100000000001 0.0014041 44104300.0 240041.0 191805.0 174278.0 141835.0 155155.0 144955.0 141280.0 134726.0 183518.0 139173.0 True False 236617.97132187203 191360.88730696365 159949.53557253472 152266.0190476895 146029.08794646655 138755.61255660912 148594.78711165077 140985.86180144412 162848.2703097873 163228.86761363383 1.4496086064993832 1.172347086055384 0.9799096073565776 0.9328375628268547 0.8946278319599722 0.8500678500389195 0.9103462474749121 0.8637311761248054 0.9976683211161679 1.0 17.31653670012912 -4.784120134913988 1.29513078667973 0.9085791685193038 1.6940125859478927 0.9248092317760379 0.047232481264369325 0.3153227432322117 0.46229819708371056 0.013622361368031558 0.3312435459961029 1.6439169185983704e-05 4.784120134913988 0.785433417428589 ICTLPSPPS(ph)PLASLAPVADSSTR ddPTM_PC-9_AZD4547_30min_R2 1 ICTLPSPPSPLASLAPVADSSTR 23 0 Q9UER7-3;Q9UER7;Q9UER7-2 Q9UER7-3 DAXX Death domain-associated protein 6 1 ICT(0.002)LPS(0.096)PPS(0.9)PLAS(0.002)LAPVADSSTR 64.16 0.0011202 6832600.0 20574.0 20032.0 25360.0 33572.0 27887.0 23423.0 21167.0 32783.0 26241.0 27168.0 True False 27116.104034215372 26506.952252889372 25023.709830070355 25832.49408222949 24015.371414659156 21958.35610722243 23050.82199408759 27717.140628396493 27628.045687936734 26216.856589295614 1.0343003533568904 1.0110652344077056 0.9544893280717558 0.9853391078462449 0.9160278743892077 0.8375663204485034 0.8792366817728743 1.0572259314914758 1.0538275477014019 1.0 14.678207095814804 -7.781102251040964 24.99902334796108 1.04164510742445 0.9445600925078281 0.3478598239417795 0.05735169778987203 309.52949932643975 393524.64741343784 0.035579757563549815 0.01712952234840165 1.655380172025375e-08 7.781102251040964 -0.0970850149166218 ICTLPSPPS(ph)PLASLAPVADSSTR ddPTM_PC-9_Lapatinib_30min_R1 2 ICTLPSPPSPLASLAPVADSSTR 23 0 Q9UER7-3;Q9UER7;Q9UER7-2 Q9UER7-3 DAXX Death domain-associated protein 6 1 ICT(0.001)LPS(0.02)PPS(0.969)PLAS(0.005)LAPVADS(0.002)S(0.002)T(0.002)R;ICT(0.003)LPS(0.117)PPS(0.88)PLASLAPVADSSTR 85.48899999999999 1.8899e-05 8361100.0 40776.0 46036.0 56692.0 44165.0 51405.0 51500.0 46444.0 47155.0 57552.0 50333.0 True False 40194.526762597394 45929.40647044339 52031.00259744851 47413.04143012105 48381.45896611851 49297.46505236358 48848.64306776266 49345.99344779097 51069.88771057261 59032.99198549326 0.6808824254151776 0.7780294531188604 0.8813885396531246 0.8031617547315288 0.8195664380014441 0.8350832880786039 0.8274803872344249 0.8359053435732553 0.8651075609232631 1.0 15.849233843700572 -14.522878745279362 0.06866698773183812 1.614294712542534 0.59057957375574 0.7111120939468176 0.041122095379841676 198.6158930160785 0.980248612686298 19.591050266900247 2.523707098491192 3.000000000006738e-15 14.522878745279362 -1.023715138786794 IDAGTMAEPS(ph)ASPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IDAGTMAEPSASPSK 15 0 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 IDAGTMAEPS(0.975)AS(0.021)PS(0.004)K 122.96 3.6921999999999996e-05 7935900.0 47675.0 56471.0 54630.0 54278.0 62423.0 58817.0 64537.0 58247.0 49583.0 50197.0 True False 55745.43587582844 62077.0676761626 55932.58638542874 51236.97963165028 50191.661257254935 55732.53297858912 58423.58815258216 56718.077967797886 50308.057573179845 59297.31874076663 0.9401004473664966 1.0468781556135507 0.9432565851746573 0.8640690796770395 0.8464406540316031 0.9398828507278403 0.9852652597665638 0.9565032479083152 0.8484035811655223 1.0 15.855679251152878 -5.51076100024548 24.330473100457045 0.9175812182794737 0.993883835736197 0.20859404771611312 0.05638918104967213 580.1587006365459 1164862.330486341 0.015403030136373435 0.029573020134912996 3.0848851487871628e-06 5.51076100024548 0.07630261745672329 IDAGTMAEPS(ph)ASPSKR ddPTM_PC-9_AZD4547_30min_R2 1 IDAGTMAEPSASPSKR 16 1 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 IDAGT(0.009)MAEPS(0.728)AS(0.253)PS(0.011)KR 82.837 0.038584 0.0 26389.0 22892.0 23877.0 24704.0 26811.0 30639.0 28480.0 33030.0 26486.0 27001.0 True False 34780.153074701535 30291.391322541123 23560.37537904535 19008.874472995274 23088.75544154719 28723.13848649565 31014.664826929402 27925.972453891824 27885.995887759316 26055.70320846477 1.3348383958949317 1.1625628017093892 0.9042310311314584 0.7295475512946364 0.8861305817317684 1.1023743345819315 1.1903215422277915 1.0717796495632272 1.0702453764018902 1.0 14.669311571247505 -6.824902653870617 24.98473715214955 1.0978920026349446 0.9915698490136748 0.05965129199310637 0.15939431135126947 183.99968782647895 72436.20014603823 0.06311404025800428 0.05566136857366433 1.4965710715347005e-07 6.824902653870617 -0.10632215362126973 IDAGTMAEPSAS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 4 IDAGTMAEPSASPSK 15 0 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 IDAGTMAEPS(0.005)AS(0.974)PS(0.021)K;IDAGTMAEPS(0.063)AS(0.909)PS(0.028)K;IDAGTMAEPS(0.052)AS(0.932)PS(0.016)K;IDAGTMAEPS(0.057)AS(0.918)PS(0.025)K 129.05 1.4287e-05 45899000.0 179741.0 179855.0 220106.0 232652.0 242133.0 229043.0 224882.0 227095.0 226221.0 241659.0 True False 236894.89915494886 237989.61149378095 217187.2506252946 179017.67583756856 208517.01246981317 214720.90500220106 244896.06234584044 192002.68587394967 238178.58022067524 233198.59196527465 1.0158504695869888 1.0205448047011352 0.9313403172590156 0.7676619070848674 0.8941606838726677 0.9207641572474627 1.0501609820281748 0.8233441045070314 1.021355138611395 1.0 17.831199552122527 -9.726293371112103 15.082564082859562 0.9999965924982407 0.933633077982252 0.04012284726254567 0.08776461877438754 0.0 0.0 0.08746662193717572 0.021213771821349554 1.8780477445217318e-10 9.726293371112103 -0.06636351451598865 IDAGTMAEPSAS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 IDAGTMAEPSASPSK 15 0 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 IDAGTMAEPS(0.012)AS(0.984)PS(0.004)K;IDAGTMAEPS(0.003)AS(0.878)PS(0.119)K;IDAGTMAEPS(0.395)AS(0.6)PS(0.005)K;IDAGTMAEPS(0.107)AS(0.863)PS(0.03)K;IDAGTMAEPS(0.099)AS(0.875)PS(0.026)K 134.02 7.3019e-06 41630900.0 187164.0 197525.0 207241.0 210335.0 252174.0 197230.0 223616.0 241804.0 196424.0 167308.0 True False 218847.16854249674 217133.9766027519 212182.41140586912 198550.6118652706 202762.31494620602 186886.91159642828 202433.4736403584 235456.90121251566 199296.32940230105 197639.61599060075 1.1073041578511496 1.0986358960193399 1.0735823905666766 1.0046093788945287 1.0259193933864397 0.9455943873383976 1.0242555503142934 1.191344660494146 1.0083824966133261 1.0 17.592512632213065 -5.544842448157707 4.487472937539013 1.0328357640857033 1.1001925930966916 0.20525188405803618 0.059521439426167146 0.3544627264129647 17.35376002804343 0.01751042077832271 0.033258518102908176 2.852052737628641e-06 5.544842448157707 0.06735682901098827 IDAGTMAEPSAS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 5 IDAGTMAEPSASPSK 15 0 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 IDAGTMAEPS(0.021)AS(0.958)PS(0.021)K;IDAGTMAEPS(0.017)AS(0.946)PS(0.037)K;IDAGTMAEPS(0.245)AS(0.742)PS(0.013)K;IDAGTMAEPS(0.024)AS(0.862)PS(0.114)K;IDAGTMAEPS(0.003)AS(0.904)PS(0.093)K 157.58 2.6209e-05 47281800.0 245598.0 277422.0 281185.0 286815.0 298471.0 245254.0 246985.0 241395.0 257590.0 224568.0 True False 242095.72748284313 276779.6464037573 258067.05470548806 307908.33188679256 280915.52259656327 234765.05813499773 259772.67479311372 252611.09295577323 228577.50165704775 263384.2795819497 0.9191730344237086 1.0508586421447363 0.9798119125222611 1.1690459748604305 1.0665614631307518 0.8913404342416444 0.9862876979804246 0.9590970780667853 0.8678479293443475 1.0 18.00680971355446 -6.752529848508026 24.99655279922427 0.9411940095872369 1.0420038767656765 0.3174750357901661 0.07032323937958537 236.24991438731166 662820.7555584953 0.023710906816717565 0.023376695455429242 1.7679507045526754e-07 6.752529848508026 0.10080986717843965 IDAGTMAEPSAS(ph)PSKR ddPTM_PC-9_Lapatinib_30min_R1 1 IDAGTMAEPSASPSKR 16 1 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 IDAGTMAEPS(0.09)AS(0.908)PS(0.001)KR 113.67 0.0026123 0.0 16475.0 16253.0 18783.0 18786.0 19875.0 17096.0 17674.0 19566.0 19494.0 15999.0 True False 16240.063478855023 16215.367177081349 17238.73424447675 20167.5851082589 18705.991575753418 16364.843932722479 18589.073240453836 20475.107789194724 17298.3804390795 18764.40583267254 0.8654717673275785 0.8641556424263214 0.9186933174542998 1.0747787746704534 0.9968869647437805 0.8721216157150071 0.9906561074311548 1.091167392763565 0.9218720056117952 1.0 14.195710988142144 -5.530811539285302 23.92018901339265 0.9917982074995033 0.8714663750831102 0.4286529049913381 0.06012987711362842 99.98173355570562 301479.03795802157 0.016915964927742642 0.02937983942421514 2.9456996335115514e-06 5.530811539285302 -0.12033183241639311 IDALPELALQFLVS(ph)LTY(ph)LDLS(ph)SNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IDALPELALQFLVSLTYLDLSSNR 24 0 A6NDA9;A6NDA9-2 A6NDA9 LRIT2 Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 2 3 IDALPELALQFLVS(0.864)LT(0.29)Y(0.884)LDLS(0.926)S(0.036)NR 63.703 0.0084226 0.0 26067.0 27226.0 25752.0 28884.0 32149.0 25188.0 28959.0 25016.0 24721.0 19357.0 True False 30479.628253282015 29928.81734963438 26366.025345003854 27265.72312319146 25849.634233527515 23867.09693906018 26215.793874996147 24359.356506642962 25082.497857462808 22866.270870072298 1.3329514211770397 1.3088630638415835 1.1530531364216492 1.1923992013440734 1.130470043865346 1.0437686614785 1.1464831333432577 1.065296420437529 1.0969212251522455 1.0 14.480933483561989 -1.5228787452804688 0.2841188774835366 1.0383636346568579 3.5322914652738335 0.8493688497865313 0.039693449059636475 18.393491025674294 0.2600564305345631 0.042157966556019506 22.885142443503874 0.02999999999999093 1.5228787452804688 2.4939278306169754 IDASKNEEDEGHS(ph)NSSPR ddPTM_PC-9_AZD4547_30min_R2 2 IDASKNEEDEGHSNSSPR 18 1 Q14103-3;Q14103;D6RAF8;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 IDASKNEEDEGHS(0.396)NS(0.396)S(0.209)PR;IDASKNEEDEGHS(0.966)NS(0.023)S(0.012)PR 140.75 0.00076056 571324000.0 92550.0 89998.0 122646.0 162576.0 159136.0 136691.0 103619.0 144512.0 110927.0 135920.0 True False 121978.97484041189 119088.09349318784 121019.63390452728 125096.61497416116 137042.71328730957 128143.69016147972 112840.89026339885 122180.99095539835 116790.37475804104 131161.48217082792 0.9299908236897132 0.9079501963700334 0.9226766265641032 0.9537603029769995 1.0448396207418713 0.9769917817380429 0.860320334871118 0.931531032839861 0.8904319532309829 1.0 17.000984584333345 -5.153710767440711 0.0028976785011614378 1.870539108504339 1.5764985844066571e-07 0.03225419607312796 0.050564581637666105 511642.4684244112 260.64910933991234 82564.53167442128 85710.26252482322 7.019226110227195e-06 5.153710767440711 -1.8705389508544805 IDASKNEEDEGHS(ph)NSSPR ddPTM_PC-9_Lapatinib_30min_R1 1 IDASKNEEDEGHSNSSPR 18 1 Q14103-3;Q14103;D6RAF8;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 IDASKNEEDEGHS(0.584)NS(0.208)S(0.208)PR 49.559 0.035391000000000006 39776000.0 9905.1 8414.4 13558.0 8432.1 10169.0 6995.9 6929.7 8005.4 7364.0 4340.3 True False 9763.851457627128 8394.91697377919 12443.31357539347 9052.224762661013 9570.879413023229 6696.701665239422 7288.485958717493 8377.360109149518 6534.588773642214 5090.51507191378 1.9180478438219035 1.6491291853936345 2.4444114985628365 1.7782532091114756 1.8801396868126854 1.315525358560975 1.4317776994573137 1.6456802486197233 1.2836792900773268 1.0 12.313595924086917 -6.71370407015378 5.422233390146304 1.381120002734197 1.9440034937466597 0.5965556540355967 0.24486753007975343 0.14786864598943636 9.704631718119233 0.0817462862614609 0.08012576778242664 1.9332852159035148e-07 6.71370407015378 0.5628834910124627 IDASKNEEDEGHSNS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 4 IDASKNEEDEGHSNSSPR 18 1 Q14103-3;Q14103;D6RAF8;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 IDASKNEEDEGHS(0.156)NS(0.74)S(0.105)PR;IDASKNEEDEGHS(0.031)NS(0.57)S(0.398)PR;IDASKNEEDEGHS(0.102)NS(0.449)S(0.449)PR;IDASKNEEDEGHS(0.188)NS(0.545)S(0.267)PR 166.21 6.334e-07 831589900.0 94245.0 84823.0 131874.0 167722.0 144848.0 146419.0 102415.0 140311.0 122179.0 121930.0 True False 124212.94958222167 112240.37594582852 130125.26459505908 129056.28417906867 124738.35545847689 137263.3967836485 111529.73659585588 118629.15897602253 128637.13250662787 117661.2678126038 1.0556825699010195 0.953927983545027 1.1059311786637076 1.096845942409982 1.0601479805329364 1.1665979751490059 0.947888278524132 1.0082260813725064 1.093283583443152 1.0 16.844279961076055 -9.835746788684725 8.375787584580129 0.9999999855810877 1.0530929453183202 0.0588885486934172 0.06494313633003851 0.0 0.0 0.06398042089697227 0.015517531372334832 1.4596650562170322e-10 9.835746788684725 0.05309295973723249 IDASKNEEDEGHSNS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IDASKNEEDEGHSNSSPR 18 1 Q14103-3;Q14103;D6RAF8;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 IDASKNEEDEGHS(0.026)NS(0.487)S(0.487)PR;IDASKNEEDEGHS(0.061)NS(0.687)S(0.252)PR;IDASKNEEDEGHS(0.133)NS(0.433)S(0.433)PR 83.77600000000001 0.0009753 212924000.0 69910.0 60123.0 70815.0 91380.0 105700.0 87171.0 94337.0 83616.0 83118.0 70813.0 True False 81744.38221456048 66091.61410093543 72503.49816738309 86260.2748579574 84988.84377379902 82599.59930422487 85400.71641926547 81421.16859847544 84333.4435061927 83650.83634460041 0.9772093835118841 0.7900891011856762 0.8667396685516 1.0311944103297113 1.015995147062089 0.9874330361020546 1.020918859286193 0.9733455414965628 1.0081601953001438 1.0 16.352092344011233 -5.755163037217406 24.99721482818323 1.0045347594879157 0.8692203131147873 0.6242100308007511 0.04509878981197392 86.69403323240384 345277.67094587017 0.011769091053435541 0.019756178488128873 1.7572638008688157e-06 5.755163037217406 -0.1353144463731284 IDASKNEEDEGHSNS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 4 IDASKNEEDEGHSNSSPR 18 1 Q14103-3;Q14103;D6RAF8;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 IDASKNEEDEGHS(0.146)NS(0.427)S(0.427)PR;IDASKNEEDEGHS(0.01)NS(0.593)S(0.397)PR;IDASKNEEDEGHS(0.038)NS(0.481)S(0.481)PR;IDASKNEEDEGHS(0.076)NS(0.616)S(0.308)PR 80.236 0.0017304000000000002 951528900.0 287029.7 280667.2 361659.3 288200.5 344067.5 335832.8 266513.5 281895.0 342839.7 231656.1 True False 282936.60384320014 280017.3323425417 331925.06839927065 309395.726178684 323830.1261127314 321470.01400849293 280312.2649694293 294992.8708082921 304225.48272390926 271697.54822264926 1.0413660546224022 1.0306214913396075 1.2216711949394055 1.138750526836341 1.191877248179512 1.1831907063992215 1.031707009515303 1.085739907253609 1.119721118994435 1.0 18.05164202128862 -10.27282231871518 6.067141001719008 0.9999999969224317 1.118161584079658 0.21984335217565143 0.06549026027551122 2.9531760178601338e-09 5.833669291419952e-10 0.06786373058168609 0.016459371946030928 5.3355314145023037e-11 10.27282231871518 0.11816158715722624 IDASKNEEDEGHSNSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 IDASKNEEDEGHSNSSPR 18 1 Q14103-3;Q14103;D6RAF8;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 IDASKNEEDEGHS(0.024)NS(0.181)S(0.795)PR;IDASKNEEDEGHS(0.01)NS(0.38)S(0.61)PR;IDASKNEEDEGHS(0.002)NS(0.2)S(0.798)PR 71.434 0.004259000000000001 83487600.0 41321.0 34995.7 52758.0 78174.0 63735.0 56205.0 51209.0 57207.0 46430.0 59351.0 True False 54460.21846980724 46307.375646787164 52058.394448535204 60152.192076260195 54886.49539618108 52690.49246494622 55766.501795022035 48366.97263608206 48884.19501127637 57273.13955503844 0.9508858584131216 0.8085356592384223 0.9089495503997653 1.0502688091414132 0.9583287352954724 0.9199861029848314 0.9736938157795846 0.8444966176439879 0.8535274195035101 1.0 15.805571069730409 -5.521412359561385 24.999799424784303 0.940639539727956 0.8744687097839486 0.12732743408027913 0.06662809386887204 104.44782853804773 1780685.4389305804 0.018782026141489737 0.033120124234681955 3.010146553858803e-06 5.521412359561385 -0.06617082994400736 IDASKNEEDEGHSNSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IDASKNEEDEGHSNSSPR 18 1 Q14103-3;Q14103;D6RAF8;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 IDASKNEEDEGHS(0.013)NS(0.258)S(0.729)PR;IDASKNEEDEGHS(0.009)NS(0.178)S(0.813)PR;IDASKNEEDEGHS(0.01)NS(0.282)S(0.708)PR 145.69 0.00045961 588581000.0 235836.0 224792.0 237080.0 347589.0 403173.0 332787.0 373801.0 337946.0 317490.0 287035.0 True False 275758.37682667765 247107.86416142652 242732.88633090685 328114.71522874193 324174.1448515961 315335.0638819681 338391.8631951181 329075.27558338485 322132.69061793096 339072.1733321897 0.8132733928493643 0.7287765956522019 0.7158738033424552 0.9676839948387251 0.9560623676835965 0.9299939325101553 0.9979936125976192 0.970516903081248 0.9500416606063893 1.0 18.37123286586911 -5.766672487047436 24.999996917609675 0.9654768702076338 0.7502547801809986 0.9108622972343785 0.030789768739255756 32.312662159922695 154367.40350828134 0.008600276574535538 0.013196127619970825 1.7113053692270272e-06 5.766672487047436 -0.21522209002663528 IDASKNEEDEGHSNSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 5 IDASKNEEDEGHSNSSPR 18 1 Q14103-3;Q14103;D6RAF8;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 IDASKNEEDEGHS(0.032)NS(0.083)S(0.885)PR;IDASKNEEDEGHS(0.022)NS(0.074)S(0.904)PR;IDASKNEEDEGHS(0.059)NS(0.251)S(0.691)PR;IDASKNEEDEGHS(0.004)NS(0.27)S(0.726)PR;IDASKNEEDEGHS(0.09)NS(0.42)S(0.49)PR 85.177 0.0008827 689480500.0 94538.0 102247.5 119008.1 94945.59999999999 109574.2 113116.4 91115.3 94674.5 111918.3 81431.0 True False 93189.87078385404 102010.75219581762 109223.71340255109 101928.21615323659 103129.2609871659 108278.67525920726 95832.80440341323 99073.42289625449 99312.88250205353 95506.23985001304 0.9757464112313843 1.0681056269833211 1.1436290819749635 1.0672414316939802 1.079816995718022 1.1337340411396426 1.0034193007065617 1.0373502616357162 1.0398575282412814 1.0 16.543307373499786 -7.2853664030573 24.7488371858323 1.0232692919046449 1.08016427578034 0.2900824985624372 0.04418376652601499 994.6135575130461 1028770.0802988323 0.01897058659844768 0.012796809579220537 5.183625252973771e-08 7.2853664030573 0.05689498387569514 IDASKNEEDEGHSNSSPR ddPTM_PC-9_AZD4547_30min_R2 2 IDASKNEEDEGHSNSSPR 18 1 Q14103-3;Q14103;D6RAF8;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 0 ; 121.32 3.1274e-05 13851500.0 52062.0 32971.0 92606.0 139160.0 122836.0 100204.0 68380.0 101737.0 80836.0 103583.0 False True 68616.63304312833 43628.23096695367 91377.98393231441 107078.81200056776 105782.34170369976 93938.22803945337 74465.68753038753 86015.88433368452 85108.82593003512 99956.59069821158 0.6864643197995348 0.43647177902131334 0.9141766770357579 1.0712531435156643 1.058282810215859 0.9397902367745933 0.7449802660358229 0.8605323944409351 0.8514578712172691 1.0 16.609014074624895 -5.276218329701207 23.475704322190897 0.9284378713422206 0.5614680917946143 0.6478409131492069 0.10869738807103063 200.91466476143052 319144.61290238675 0.030915146293544242 0.06487955058196379 5.2939723696666e-06 5.276218329701207 -0.36696977954760623 IDASKNEEDEGHSNSSPR ddPTM_PC-9_Lapatinib_30min_R1 2 IDASKNEEDEGHSNSSPR 18 1 Q14103-3;Q14103;D6RAF8;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 0 ; 96.096 0.0003855 13180800.0 73214.0 68299.0 113894.0 89499.0 102811.0 95908.0 73654.0 81528.0 118551.0 69802.0 False True 72169.95493419694 68140.85786177799 104530.07496355397 96081.05501991198 96763.8591142031 91806.23841246775 77467.44372821008 85316.08851259672 105198.53798262599 81867.18269468132 0.8815492674683871 0.832334222565166 1.276825115057306 1.1736211245749157 1.1819615128943428 1.1214046384722134 0.9462575989346086 1.0421280628500174 1.284990328480675 1.0 16.320997628096933 -5.243684048825207 24.66606403039037 1.12667636074719 0.8569416750568032 0.5176193834197828 0.10481094370725118 569.6406485884222 791352.7242205436 0.027720309348907114 0.07298426026874096 5.705792202546755e-06 5.243684048825207 -0.2697346856903867 IDEDGENTQIEDTEPMS(ph)PVLNSK ddPTM_PC-9_AZD4547_30min_R2 4 IDEDGENTQIEDTEPMSPVLNSK 23 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 IDEDGENTQIEDTEPMS(1)PVLNSK;IDEDGENTQIEDTEPMS(0.998)PVLNS(0.002)K;IDEDGENTQIEDTEPMS(0.999)PVLNS(0.001)K;IDEDGENTQIEDTEPMS(0.997)PVLNS(0.003)K 175.77 2.532e-14 77724900.0 256700.0 255234.0 312778.0 362899.0 333136.0 349623.0 300289.0 360442.0 310547.0 344088.0 True False 338325.2603083056 337733.3991270948 308630.35935448547 279238.24228365923 286885.8167459359 327761.0185405553 327014.1392631244 304743.9710331715 326961.8804257343 332041.5838522358 1.018924365988045 1.0171418748483982 0.9294930947318673 0.8409737089072705 0.8640056869310833 0.9871083457017076 0.9848589910613463 0.9177885718337851 0.9847016046376829 1.0 18.341004405950542 -9.604014457207306 14.053643033667228 1.0000036903443936 0.9463635002335005 0.06136777679246386 0.05820435353475356 0.0 0.0 0.06230157125176907 0.015110350524293447 2.488774468214496e-10 9.604014457207306 -0.05364019011089316 IDEDGENTQIEDTEPMS(ph)PVLNSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IDEDGENTQIEDTEPMSPVLNSK 23 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 IDEDGENTQIEDTEPMS(0.999)PVLNS(0.001)K;IDEDGENTQIEDTEPMS(0.999)PVLNS(0.001)K;IDEDGENTQIEDTEPMS(0.999)PVLNS(0.001)K;IDEDGENTQIEDTEPMS(0.999)PVLNS(0.001)K 159.19 1.9486e-07 65909200.0 289044.0 296401.0 300850.0 365103.0 376965.0 318570.0 345303.0 267952.0 280905.0 264564.0 True False 337973.4403207745 325825.73243403307 308023.40497997875 344647.46258989704 303101.4143158947 301863.62838956655 312593.4000627711 260918.5439186117 285012.704204951 312527.35891252867 1.0814203322767906 1.0425510699856084 0.985588609111785 1.1027753339391906 0.9698396177875994 0.965879049565236 1.0002113131806196 0.8348662492349623 0.9119608126363152 1.0 18.25362296449869 -6.837443196816048 1.1056569009360473 0.9167851610382296 1.048673845324934 0.46558424293411915 0.054315515721813215 0.41706973765767846 1.0764947954718567 0.02999761098299633 0.025153335558064302 1.453974544557458e-07 6.837443196816048 0.13188868428670442 IDEDGENTQIEDTEPMS(ph)PVLNSK ddPTM_PC-9_Lapatinib_30min_R1 4 IDEDGENTQIEDTEPMSPVLNSK 23 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 IDEDGENTQIEDT(0.001)EPMS(0.987)PVLNS(0.011)K;IDEDGENTQIEDT(0.001)EPMS(0.992)PVLNS(0.007)K;IDEDGENTQIEDTEPMS(0.999)PVLNS(0.001)K;IDEDGENTQIEDTEPMS(0.993)PVLNS(0.007)K 192.93 4.465299999999999e-22 58035000.0 206757.0 270871.0 285547.0 253282.0 295007.0 308247.0 281290.0 275940.0 298283.0 253230.0 True False 203808.6072654102 270243.8148417652 262070.42790329593 271909.20320398314 277655.26826607744 295063.994368853 295853.8198374593 288761.17976849596 264687.2274807608 297000.46809223463 0.6862231853524104 0.9099104004032746 0.8823906224346723 0.9155177597886502 0.9348647497075679 0.9934798967293874 0.9961392375502276 0.9722583321950189 0.8912013815364127 1.0 18.180105679246736 -4.0116739314105265 0.8901739381844278 0.9601469077374745 1.1684195730293734e-30 0.7934581566819946 0.0400173180227465 3.4130058433054358 0.7841983292516463 0.013901393029552742 4.424320852452699 9.734778372858762e-05 4.0116739314105265 -0.9601469077374745 IDEEFCRR ddPTM_PC-9_AZD4547_30min_R2 1 IDEEFCRR 8 1 P35968 P35968 KDR Vascular endothelial growth factor receptor 2 0 61.998999999999995 0.040289 2950400.0 9781.5 16350.0 11185.0 12498.0 13516.0 14845.0 11124.0 18387.0 13946.0 12929.0 False True 12891.813532160879 21634.817758323734 11036.67959185083 9616.779192175152 11639.536703142443 13916.739803258199 12114.01444995655 15545.711641226439 14683.15708867672 12476.359645281327 1.0332992875078493 1.7340649334765064 0.8846073618938199 0.7708000943858897 0.9329273148634042 1.115448752595204 0.9709574582949908 1.2460134272504695 1.176878312756079 1.0 13.606909425301808 -5.285622544602005 24.907568680144763 1.0117516076767976 1.3836822796323782 0.34419890298777545 0.20510332312331722 709.2074736910101 730450.6378546542 0.05398353059563329 0.11246234384957471 5.1805689159286175e-06 5.285622544602005 0.3719306719555806 IDEPLEGSEDR ddPTM_PC-9_AZD4547_30min_R2 4 IDEPLEGSEDR 11 0 P61978;P61978-2;P61978-3;S4R359 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 ;;; 174.86 0.00026363 104688000.0 136387.0 136709.0 200389.0 215017.0 192232.0 200635.0 181964.0 216580.0 178058.0 186385.0 False True 179755.2289741684 180897.51075979683 197731.7109281535 165448.15262953474 165543.9049658536 188089.26173302147 198158.4434890228 183112.53751328756 187469.7823673884 179859.7178811783 0.9994190533142115 1.0057700128235725 1.09936629089334 0.9198733022523456 0.9204056745781052 1.0457553472716992 1.1017388764055176 1.018085314880001 1.0423111109917207 1.0 17.45651258531531 -6.927889911607258 24.99994157972748 1.0465755272410318 0.9912834144339973 0.1939937965296148 0.05303128333213593 76.27463125657306 26442.01889749128 0.019860826937089987 0.017515602431830767 1.1806198705662041e-07 6.927889911607258 -0.0552921128070345 IDEPLEGSEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IDEPLEGSEDR 11 0 P61978;P61978-2;P61978-3;S4R359 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 ;;; 162.64 0.0017464000000000002 77635000.0 117179.0 129695.0 155612.0 163534.0 167866.0 124827.0 148373.0 127610.0 127730.0 104271.0 False True 137015.09030925433 142570.26247560515 159322.38024179652 154371.72016438143 134973.86233616364 118280.85237462535 134318.03531250395 124260.37271397152 129597.80960858046 123174.50689121817 1.1123656490888938 1.1574656645592776 1.2934687888176604 1.2532765428540757 1.0957938110957173 0.96027055727599 1.0904694380561004 1.0088156701427864 1.0521479880819415 1.0 16.9103441705073 -6.467876470460398 4.75376870434503 1.0267593176860206 1.2056948214046728 0.699947742530149 0.05601158199358284 0.12707694285468873 6.061567293153959 0.01892663110964078 0.021015838449759336 3.4050502825094827e-07 6.467876470460398 0.1789355037186522 IDEPLEGSEDR ddPTM_PC-9_Lapatinib_30min_R1 4 IDEPLEGSEDR 11 0 P61978;P61978-2;P61978-3;S4R359 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 ;;; 164.46 0.0013898 138160000.0 118624.0 161497.0 188509.0 167037.0 201384.0 176061.0 172204.0 166540.0 181757.0 150344.0 False True 116932.4000070229 161123.06361884574 173010.5176857832 179321.45819909684 189538.9890561775 168531.28144823638 181119.88051935664 174278.05638416077 161285.61267393918 176330.76007921205 0.6631423805721363 0.9137547161168327 0.981170373269319 1.016960728341109 1.074905983340808 0.9557679067028807 1.0271598695428592 0.9883587883694872 0.9146765578591379 1.0 17.427924642474345 -4.674196147308238 1.9234784149686754 0.9986035572329799 0.49025611421479576 0.8598463465970514 0.04027491691431117 0.3859619229523966 1.2078037799121804 0.011093802729792221 0.3868247261008069 2.117404602218234e-05 4.674196147308238 -0.5083474430181841 IDFSSIAVPGT(ph)SSPR ddPTM_PC-9_AZD4547_30min_R2 1 IDFSSIAVPGTSSPR 15 0 Q5TDH0-2;Q5TDH0;Q5TDH0-3 Q5TDH0-2 DDI2 Protein DDI1 homolog 2 1 IDFSSIAVPGT(0.366)S(0.366)S(0.268)PR 89.46600000000001 0.011065 59318000.0 25847.0 25216.0 33745.0 51611.0 44637.0 32869.0 34756.0 42115.0 26676.0 35421.0 True False 34065.80834900188 33366.57887424412 33297.519251408696 39712.88133200129 38439.923040705035 30813.69623397062 37849.216668706395 35607.09445642307 28086.038899866635 34180.92157131331 0.9966322376044994 0.9761755195695884 0.9741551052665 1.1618434935742263 1.1246017156239034 0.9014881640824843 1.1073199588764668 1.0417242373683302 0.8216875850251543 1.0 15.060903674411367 -9.973332129024424 6.788384932207734 0.9999999999617313 1.0177703601583385 0.0 0.09839317579080235 0.0 0.0 0.09587985984335755 0.02325428173550473 1.0633295202710779e-10 9.973332129024424 0.01777036019660727 IDFSSIAVPGT(ph)SSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IDFSSIAVPGTSSPR 15 0 Q5TDH0-2;Q5TDH0;Q5TDH0-3 Q5TDH0-2 DDI2 Protein DDI1 homolog 2 1 IDFSSIAVPGT(0.333)S(0.333)S(0.333)PR 125.33 6.533e-05 8621900.0 34398.0 36050.0 43069.0 42350.0 54536.0 56194.0 63048.0 53871.0 56425.0 48359.0 True False 40220.90200853165 39628.80575385 44095.928300092084 39977.26680055252 43850.062289951704 53247.08771611668 57075.63701200861 52456.94333104265 57250.108879387546 57126.10389036666 0.7040722063895944 0.6937074831832303 0.7719050538562653 0.6998073398682104 0.7676011368481628 0.932097309109433 0.9991165706232144 0.9182657272009165 1.0021707237248119 1.0 15.801862518263182 -6.7503350388183705 2.8881237056832605 0.9732833774781887 0.7199955408330337 0.9412274130085633 0.030708183924650887 0.05672727961521032 0.9723903439959416 0.010978866890338538 0.010266938243470178 1.77690807583493e-07 6.7503350388183705 -0.253287836645155 IDFSSIAVPGTS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IDFSSIAVPGTSSPR 15 0 Q5TDH0-2;Q5TDH0;Q5TDH0-3 Q5TDH0-2 DDI2 Protein DDI1 homolog 2 1 IDFSSIAVPGT(0.001)S(0.5)S(0.5)PR 164.7 0.00029998 8824900.0 69369.0 60255.0 81905.0 75118.0 98955.0 99248.0 99038.0 91809.0 84837.0 81381.0 True False 81111.80159979747 66236.71818857791 83857.92582644231 70909.38199584204 79565.47810441109 94043.26016388134 89656.40366697294 89399.1110296765 86077.5806291643 96134.73108835824 0.8437304674545449 0.6889988398438353 0.8722958381125318 0.7376042060248613 0.8276455054654679 0.9782443774398806 0.932611998306512 0.9299356228240657 0.8953848380774027 1.0 16.552770114572994 -6.626434402238975 4.80251433198152 0.9413463220913821 0.78465534988302 0.666268821281839 0.0546674255210285 0.1247871187125219 4.794997586198812 0.0172718125725512 0.017236303775070207 2.3635543739091235e-07 6.626434402238975 -0.15669097220836214 IDFSSIAVPGTS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 IDFSSIAVPGTSSPR 15 0 Q5TDH0-2;Q5TDH0;Q5TDH0-3 Q5TDH0-2 DDI2 Protein DDI1 homolog 2 1 IDFSSIAVPGT(0.034)S(0.839)S(0.127)PR 226.39 2.3317e-24 31043000.0 55592.0 51297.0 68127.0 48638.0 54512.0 65856.0 64262.0 52848.0 69684.0 52310.0 True False 54799.24788567575 51178.22494817826 62525.86103782506 52215.00077161161 51305.71133471551 63039.49239783403 67589.17192361911 55303.51101110925 61835.45411494903 61351.713801306374 0.8931983230843162 0.8341775930485663 1.019137969646965 0.851076482406263 0.8362555527116025 1.0275098850864002 1.1016672189877754 0.9014175413292475 1.0078847074298414 1.0 15.904816024303353 -6.771360476351181 24.999686636185114 1.0074076943984376 0.8892183206541817 0.44935082928212355 0.06690461779135758 207.26837186025054 522282.26743060834 0.023992521239777447 0.021409652840001632 1.6929320370169226e-07 6.771360476351181 -0.11818937374425587 IDFSSIAVPGTSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 IDFSSIAVPGTSSPR 15 0 Q5TDH0-2;Q5TDH0;Q5TDH0-3 Q5TDH0-2 DDI2 Protein DDI1 homolog 2 1 IDFSSIAVPGT(0.1)S(0.205)S(0.696)PR 184.87 4.5985e-07 70228000.0 70559.0 62056.0 88975.0 126590.0 96001.0 83631.0 65616.0 95120.0 68724.0 83429.0 True False 92995.2942816276 82114.38842877909 87795.13336476778 97406.63129600364 82672.91824788244 78401.54034936265 71455.69688496472 80421.38964015112 72356.61033717336 80508.17610381143 1.1551037271259832 1.019950921790807 1.0905120152214125 1.2098973794959964 1.026888475790082 0.9738332694094028 0.8875582623164389 0.9989220167707139 0.8987485972092198 1.0 16.296847684831896 -6.600452212813679 3.2886898996315113 0.9472382513173215 1.1107493238041308 0.6475919601865958 0.05760893387951746 0.1571315717748664 3.419445515020321 0.019827387155009674 0.020095042318109668 2.509272269698109e-07 6.600452212813679 0.1635110724868093 IDFSSIAVPGTSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IDFSSIAVPGTSSPR 15 0 Q5TDH0-2;Q5TDH0;Q5TDH0-3 Q5TDH0-2 DDI2 Protein DDI1 homolog 2 1 IDFSSIAVPGTS(0.004)S(0.996)PR;IDFSSIAVPGTS(0.021)S(0.979)PR 301.75 2.751099999999999e-105 60901000.0 180608.0 167416.0 192956.0 205270.0 255820.0 263590.0 270430.0 241260.0 242480.0 204112.0 True False 211181.36722939965 184035.9540662011 197556.80282970506 193769.38739431865 205693.90741923553 249766.8763763248 244812.91265634855 234927.1806360996 246025.81127290844 241115.8898502972 0.8758500626421464 0.7632676310983255 0.8193437726247039 0.8036359093323348 0.853091463805831 1.0358789565109077 1.015332970416619 0.9743330511396823 1.0203633258084306 1.0 17.879367203987123 -6.67073366446824 4.585229772478293 1.0078712275040584 0.8140965480213674 0.9055608358271221 0.030181041025603487 0.058340460175307106 2.166173346854838 0.010002045393427583 0.009884866113862236 2.1343534259387164e-07 6.67073366446824 -0.193774679482691 IDFSSIAVPGTSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 IDFSSIAVPGTSSPR 15 0 Q5TDH0-2;Q5TDH0;Q5TDH0-3 Q5TDH0-2 DDI2 Protein DDI1 homolog 2 1 IDFSSIAVPGT(0.021)S(0.375)S(0.605)PR 175.27 6.2535e-05 31094000.0 55194.0 42051.0 51185.0 41524.0 43093.0 50175.0 50260.0 49459.0 54713.0 41599.0 True False 54406.923438660066 41953.63349310572 46976.76687981378 44577.81348000331 40558.35446409774 48029.13221363773 52862.21687593132 51757.045698956485 48550.64578656796 48789.331722816736 1.1151397553005673 0.859893587628005 0.9628491561782287 0.9136795259516974 0.8312955523662213 0.9844187349501347 1.0834790108676537 1.0608271085367598 0.995107825259735 1.0 15.574278102067723 -7.000085159936413 24.99999998474156 1.039069057764652 0.9300354600314941 0.2739296022705122 0.07495461622710443 3.634306222372722 1067194.1388099457 0.025907799758772016 0.022616933687780734 9.998039312238907e-08 7.000085159936413 -0.1090335977331579 IDFTPVS(ph)PAPSPTR ddPTM_PC-9_AZD4547_30min_R2 2 IDFTPVSPAPSPTR 14 0 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 IDFTPVS(0.996)PAPS(0.003)PT(0.001)R;IDFT(0.142)PVS(0.854)PAPS(0.004)PTR 136.14 5.0703e-05 16226000.0 40622.0 49441.0 45881.0 54945.0 51781.0 51323.0 39395.0 62070.0 52875.0 39695.0 True False 53538.95100991046 65421.836378549495 45272.58796188716 42278.27914178778 44592.10195512126 48113.76469670734 42901.078681772575 52478.507726705 55669.864553548075 38305.29013221767 1.3976907843567048 1.7079060399421109 1.1818886583451162 1.1037190684591245 1.1641238534208596 1.2560605736344495 1.1199779073253775 1.3700067939850056 1.4533205299161922 1.0 15.22525602810913 -5.274861367704778 24.76966531156918 1.2128992841020223 1.552798412194152 0.4875841225611708 0.1420163140052862 506.58846082428823 934886.164431449 0.03731547017610285 0.07838197412328789 5.310539363152349e-06 5.274861367704778 0.33989912809212974 IDFTPVS(ph)PAPSPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IDFTPVSPAPSPTR 14 0 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 IDFT(0.01)PVS(0.649)PAPS(0.155)PT(0.187)R;IDFT(0.074)PVS(0.922)PAPS(0.003)PT(0.001)R 107.11 0.0031612 0.0 20748.3 36751.0 33952.0 31692.0 33167.0 23780.0 28833.0 20567.0 20268.4 20919.0 True False 24260.577392395426 40399.3964011024 34761.54444367705 29916.399986850312 26668.164441301662 22532.93493770252 26101.729507157157 20027.13804253781 20564.78700595441 24711.449105287116 0.9817545417522591 1.634845298993768 1.4066979356641482 1.2106291241515892 1.0791825411645284 0.9118419094605629 1.0562605776758185 0.8104396450895678 0.8321967246167886 1.0 14.592891993846752 -6.313192510431732 1.650786275698623 0.9139846479403559 1.3667081601729285 0.5512429032060532 0.16532633472065553 0.26410011964514485 1.4285459202545938 0.05970443489714466 0.07704264971342059 4.861916429466078e-07 6.313192510431732 0.45272351223257257 IDFTPVS(ph)PAPSPTR ddPTM_PC-9_Lapatinib_30min_R1 2 IDFTPVSPAPSPTR 14 0 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 IDFT(0.122)PVS(0.867)PAPS(0.01)PTR;IDFT(0.001)PVS(0.999)PAPSPTR 127.3 0.00060306 0.0 12077.1 23672.4 24991.0 19178.6 22629.0 30339.0 29716.0 30297.0 25589.0 25112.9 True False 11904.878339331113 23617.58801222791 22936.336448049748 20589.058221934098 21298.00671032576 29041.47169366326 31254.54907849532 31704.709224636263 22706.89735588412 29453.63130416415 0.4041905127551455 0.801856578169662 0.7787269491896917 0.699032931094755 0.7231029169335277 0.9860064925019069 1.0611441677847226 1.0764278569669559 0.770937108616343 1.0 14.846157892774949 -6.738966714717513 4.8811403059186285 0.9904642160253303 0.6913524588476447 0.575189226111456 0.12775367453458303 0.14418824320826973 8.651837738276257 0.04378335615477179 0.04191506973453201 1.8240354950471499e-07 6.738966714717513 -0.29911175717768557 IDFTPVSPAPS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 3 IDFTPVSPAPSPTR 14 0 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 IDFTPVSPAPS(0.969)PT(0.031)R;IDFTPVSPAPS(0.994)PT(0.006)R;IDFT(0.002)PVS(0.281)PAPS(0.691)PT(0.026)R 107.74 0.0007523 5480600.0 24222.1 23217.5 33537.7 37882.0 39538.7 36645.0 35973.0 43779.0 33766.3 38142.0 True False 31924.22394902151 30722.102832041703 33092.968184856094 29148.890171065716 34049.43399264115 34353.58235704928 39174.52731106501 37013.96149133913 35551.1176827323 36806.66018952125 0.8673491097709062 0.8346886860652517 0.8991027171293734 0.7919460777200404 0.925088932745246 0.9333523384126453 1.0643325721310049 1.0056321682203835 0.9658881707733319 1.0 15.167679226076247 -6.766050067209974 2.0380049556116124 1.0075882001972305 0.8522648330691563 0.7640573583534348 0.03855306391557106 0.14589719190304992 1.247673054755369 0.014876366806787649 0.01362801629256697 1.7137597270239134e-07 6.766050067209974 -0.15532336712807415 IDFTPVSPAPS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 1 IDFTPVSPAPSPTR 14 0 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 IDFTPVS(0.001)PAPS(0.967)PT(0.031)R 113.59 0.00019482 2389400.0 8357.9 8659.3 7906.2 7843.5 9519.8 11874.0 9138.4 10841.0 11783.0 13068.0 True False 8238.71481334885 8639.249922875806 7256.182754814566 8420.337155148974 8959.864080646914 11366.176699645917 9611.541637465396 11344.712437016258 10455.874459509263 15326.786387984537 0.5375370025256961 0.5636700156301886 0.47343145334778486 0.5493869975085002 0.5845885663070907 0.7415890332076692 0.6271074310137434 0.7401885920397486 0.6821961365434156 1.0 13.903767614176056 -10.656810860774497 0.14195561227821216 1.458767262729136 0.38253143014008356 0.866359599840353 0.05250232775689982 11.037143987141945 0.30760590646042507 2.2828662857073847 0.4358545408743815 2.203886066652353e-11 10.656810860774497 -1.0762358325890524 IDFYFDENPYFENK ddPTM_PC-9_AZD4547_30min_R2 1 IDFYFDENPYFENK 14 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;A0A087X027;P0DME0;Q01105-2 Q01105;Q01105-2 SET;SETSIP Protein SET;Protein SETSIP 0 147.24 0.0002744 3228400.0 25751.0 26248.0 35358.0 46418.0 37060.0 39697.0 34125.0 40414.0 33994.0 33878.0 False True 33939.28234592596 34732.152692384225 34889.12981749321 35717.04725095104 31914.858702164747 37214.740314580056 37162.05889111537 34168.94492133165 35790.853439873514 32691.941531660672 1.0381543816557146 1.0624071580070489 1.0672088650257943 1.0925336819277218 0.9762301413409982 1.1383459828636748 1.1367345330385346 1.045179433232516 1.0947913082865295 1.0 14.996647438970992 -6.7918935068536435 24.99998269864544 1.0891916795775298 1.051763835337165 0.11402800531112223 0.047439063828992045 438.4786299801007 359946.80806160317 0.016436648510484406 0.014497257986394962 1.6147544614693786e-07 6.7918935068536435 -0.03742784424036483 IDFYFDENPYFENK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IDFYFDENPYFENK 14 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;A0A087X027;P0DME0;Q01105-2 Q01105;Q01105-2 SET;SETSIP Protein SET;Protein SETSIP 0 ; 161.48 0.00083788 8735000.0 23640.0 22500.0 25463.0 30404.0 30555.0 24333.0 31815.0 27602.0 28584.0 20883.0 False True 27641.785088717043 24733.651302680286 26070.134488965265 28700.562451097943 24567.96709090277 23056.934644201643 28801.25287934673 26877.476746736444 29001.9869243848 24668.922590262962 1.1205104311944087 1.0026238970178158 1.056800693000487 1.163429912517797 0.9959075837628985 0.9346551135274312 1.1675115836114722 1.0895277914303894 1.1756487061105838 1.0 14.590407087176638 -7.310683161313077 24.99985288489655 1.1156326369985756 1.0472971017142219 0.13903366775278014 0.0752382174432213 743.7723638395914 377591.787305249 0.03146310564420516 0.02121243841643048 4.890089847844378e-08 7.310683161313077 -0.06833553528435377 IDFYFDENPYFENK ddPTM_PC-9_Lapatinib_30min_R1 2 IDFYFDENPYFENK 14 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;A0A087X027;P0DME0;Q01105-2 Q01105;Q01105-2 SET;SETSIP Protein SET;Protein SETSIP 0 ; 134.99 0.00015039 2934100.0 101625.0 79629.0 99539.0 84019.2 102729.3 110188.6 88303.9 84438.2 106948.0 79744.0 False True 100175.80886425763 79444.62394289099 91355.28765165157 90198.25224783472 96686.96454757462 105476.09044017228 92875.84386769893 88361.50702880402 94902.39002763273 93527.64414779928 1.0710823497911743 0.8494239822543455 0.9767731079303699 0.9644020553462974 1.0337795357571795 1.1277530980411652 0.9930309344788978 0.9447635277669204 1.0146988186472545 1.0 16.513105227761997 -6.197810989251808 5.724241826150921 1.0203196283551628 0.9572017309993619 0.13194130610233645 0.06604614241068217 0.42576505590456626 28.063469278030386 0.020119895435196045 0.025998544515472993 6.34145639845056e-07 6.197810989251808 -0.06311789735580087 IDGATQS(ph)SPAEPK ddPTM_PC-9_AZD4547_30min_R2 7 IDGATQSSPAEPK 13 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 IDGAT(0.02)QS(0.687)S(0.292)PAEPK;IDGATQS(0.5)S(0.5)PAEPK;IDGAT(0.008)QS(0.496)S(0.496)PAEPK;IDGAT(0.075)QS(0.462)S(0.462)PAEPK;IDGAT(0.013)QS(0.69)S(0.297)PAEPK;IDGAT(0.007)QS(0.497)S(0.497)PAEPK;IDGAT(0.032)QS(0.484)S(0.484)PAEPK 200.19 4.2424999999999995e-07 1431425300.0 458610.0 429911.0 492839.0 554403.0 556282.0 561214.0 466258.0 506436.0 452991.0 522261.0 True False 604438.4403194089 568871.3233821847 486303.63284471777 426593.95379096473 479051.8464262702 526121.1998616196 507754.0587385693 428177.95294154214 476935.17946054443 503976.8013538754 1.1993378240737569 1.1287648992056336 0.9649325753453717 0.8464555365345576 0.9505434479113976 1.0439393211121144 1.0074949032863156 0.8495985366613932 0.9463435185494913 1.0 18.942997800737388 -5.189386144391965 3.1876230241679444 0.9461305086935359 1.1857725383234727 0.6751169687166432 0.059960227845251235 0.15413032183619113 3.016257943434765 0.01707855876299767 0.05550580468521169 6.465674773514994e-06 5.189386144391965 0.23964202962993686 IDGATQS(ph)SPAEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 IDGATQSSPAEPK 13 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 IDGAT(0.003)QS(0.499)S(0.499)PAEPK;IDGAT(0.008)QS(0.496)S(0.496)PAEPK;IDGAT(0.013)QS(0.595)S(0.393)PAEPK;IDGAT(0.015)QS(0.492)S(0.492)PAEPK;IDGAT(0.021)QS(0.489)S(0.489)PAEPK;IDGAT(0.002)QS(0.499)S(0.499)PAEPK 185.95 4.2983000000000005e-05 519763900.0 473542.0 512510.0 441693.0 516378.0 570291.0 454708.0 546971.0 460367.0 451687.0 371218.0 True False 553703.3077191714 563388.6057394091 452224.63625003083 487447.01478006353 458546.5724181976 430862.31201231456 495157.94715289 448282.85404915665 458292.067867149 438516.88483992935 1.2626727199370857 1.2847592081774943 1.0312593468666666 1.111580948491858 1.045675977985613 0.9825444057179031 1.129165065864308 1.0222704519411885 1.0450956022695412 1.0 18.74227286831742 -5.260276657348005 24.974754874421677 1.0497861481509718 1.2737159858130391 0.8175070339616429 0.04301497804326123 36.64498557515267 787093.0829739235 0.010811883916270162 0.0255541807328019 5.491909129155864e-06 5.260276657348005 0.2239298376620673 IDGATQS(ph)SPAEPK ddPTM_PC-9_Lapatinib_30min_R1 5 IDGATQSSPAEPK 13 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 IDGAT(0.003)QS(0.498)S(0.498)PAEPK;IDGAT(0.003)QS(0.66)S(0.337)PAEPK;IDGAT(0.007)QS(0.497)S(0.497)PAEPK;IDGAT(0.002)QS(0.499)S(0.499)PAEPK;IDGAT(0.002)QS(0.702)S(0.296)PAEPK 194.55 1.6597000000000002e-07 70966100.0 366636.0 374973.0 330349.0 314844.0 378641.0 352647.0 308376.0 333385.0 337086.0 270201.0 True False 361407.7034071923 374104.77305677335 303188.9804040175 337998.6780487958 356370.08081684756 337565.1098703082 324342.200384644 348875.2841817792 299119.82500705624 316904.8828297989 1.1404295830976345 1.1804954525036302 0.9567191824142771 1.0665619129331174 1.1245332594267547 1.0651937794584418 1.0234686114282419 1.100883271556124 0.9438788772708985 1.0 18.273690363188408 IDGATQSS(ph)PAEPK ddPTM_PC-9_AZD4547_30min_R2 3 IDGATQSSPAEPK 13 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 IDGAT(0.006)QS(0.184)S(0.81)PAEPK;IDGAT(0.001)QS(0.225)S(0.774)PAEPK;IDGAT(0.004)QS(0.23)S(0.766)PAEPK 206.67 7.0867e-10 40809400.0 232210.0 238585.0 263671.0 305040.0 279543.0 292743.0 265086.0 277419.0 265601.0 258941.0 True False 306047.94973195053 315702.93546603475 260174.5502604288 234717.74082102024 240733.27971341755 274437.7339323148 288678.14046037267 234550.2680044266 279640.1266248115 249875.55440550615 1.224801483522818 1.263440660360484 1.0412165002672054 0.9393385494609556 0.9634126887128294 1.0982976489446756 1.1552876436720034 0.9386683245684402 1.1191175835112004 1.0 17.930850242355937 -5.267441914738796 20.313557013406317 1.0307506592591364 1.2441211522729316 0.5852451520433768 0.0714507756832243 23.231722290806776 78626.7688612404 0.019266141722268433 0.04224753280680732 5.402043602442124e-06 5.267441914738796 0.21337049301379518 IDGATQSS(ph)PAEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 IDGATQSSPAEPK 13 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 IDGAT(0.004)QS(0.222)S(0.774)PAEPK;IDGATQS(0.063)S(0.937)PAEPK;IDGATQS(0.205)S(0.794)PAEPK;IDGATQS(0.225)S(0.775)PAEPK;IDGATQS(0.228)S(0.772)PAEPK;IDGAT(0.001)QS(0.206)S(0.793)PAEPK 206.45 7.3322e-10 1126357400.0 924752.0 1014577.0 834227.0 1040152.0 1113149.0 956015.0 1052923.0 916699.0 888343.0 734413.0 True False 1081294.2489154506 1115297.4994541965 854118.1355035161 981875.6556582827 895035.4442569559 905879.8904317772 953182.5109376208 892636.6225728774 901333.3357951584 867556.2632898925 1.2463678664655529 1.2855621550409138 0.9845103673905631 1.1317717330918404 1.031674235009103 1.0441742268064047 1.098698206987777 1.0289092020244046 1.0389335815260887 1.0 19.726597797703718 -5.2538589626994066 24.996867687899876 1.0504015086265783 1.265965038007018 0.8159947675550245 0.04193646000063176 214.17947901499184 706265.1698800578 0.010094494491054842 0.025633207334360534 5.57366724603284e-06 5.2538589626994066 0.21556352938043966 IDGATQSS(ph)PAEPK ddPTM_PC-9_Lapatinib_30min_R1 7 IDGATQSSPAEPK 13 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 IDGAT(0.003)QS(0.23)S(0.767)PAEPK;IDGAT(0.015)QS(0.185)S(0.8)PAEPK;IDGAT(0.001)QS(0.122)S(0.877)PAEPK;IDGAT(0.052)QS(0.179)S(0.769)PAEPK;IDGATQS(0.225)S(0.775)PAEPK;IDGAT(0.001)QS(0.082)S(0.917)PAEPK;IDGATQS(0.226)S(0.774)PAEPK 222.56 7.822499999999999e-16 1737892400.0 678784.0 637532.0 633264.0 605950.0 667930.0 656527.0 609658.0 576608.0 647510.0 487527.0 True False 669104.4156862586 636055.8338238499 581199.4783897306 650513.5843899423 628643.6706009052 628448.8706491868 641223.1081604965 603399.3126909948 574580.6052174192 571795.3923611073 1.1701815450511666 1.1123836293912632 1.0164465928796507 1.1376684616218837 1.0994206651527132 1.0990799839329608 1.1214205583446593 1.0552713798538773 1.0048709956280182 1.0 19.125139468934393 -8.048066731158023 2.761912008704892 1.0018023390645 1.1051460438338867 0.5665461971108579 0.037027682220213444 0.21832877676402573 3.1191593478020025 0.02995843167091289 0.010176238597378186 8.952271995890244e-09 8.048066731158023 0.10334370476938681 IDGATQSS(ph)PAEPKSEDADR ddPTM_PC-9_AZD4547_30min_R2 3 IDGATQSSPAEPKSEDADR 19 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 IDGATQS(0.026)S(0.974)PAEPKSEDADR;IDGAT(0.006)QS(0.031)S(0.963)PAEPKSEDADR;IDGAT(0.002)QS(0.049)S(0.945)PAEPKS(0.004)EDADR 145.77 1.3287999999999999e-05 80344000.0 89715.0 45150.4 85043.0 227353.0 166099.0 94418.0 61219.0 71489.0 57100.0 107890.0 True False 118242.50381207533 59744.38383580555 83915.27425389095 174940.27841883505 143039.020927438 88514.02753412133 66667.37240308258 60442.0177037927 60118.18942803961 104112.8039391604 1.1357152947409985 0.5738428087165717 0.8060034028372521 1.6802955237000778 1.3738850123662465 0.8501742742981506 0.6403378823803505 0.5805435586876783 0.5774331989288313 1.0 16.66778797865163 -6.982314642215927 8.135886314557762 0.6755757093469016 1.100227837383336 0.29870224909635024 0.30024709551185996 0.24404445386428883 85.31014942568649 0.1190076583227968 0.10323953167024058 1.0415625538258166e-07 6.982314642215927 0.4246521280364345 IDGATQSS(ph)PAEPKSEDADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IDGATQSSPAEPKSEDADR 19 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 IDGAT(0.001)QS(0.057)S(0.942)PAEPKSEDADR;IDGAT(0.001)QS(0.122)S(0.876)PAEPKS(0.001)EDADR 139.44 6.390399999999999e-05 32517000.0 34210.0 10424.4 20358.9 46093.0 45095.0 54607.0 42223.0 67239.0 58265.0 33296.0 True False 40001.0773217009 11459.265539540469 20844.333387558207 43510.558645522215 36258.95846716613 51743.31278987051 38223.33177195212 65474.04749560937 59117.01539844954 39332.30122900903 1.0170032281812849 0.2913449043527826 0.5299545853214594 1.1062296709309134 0.9218621167383871 1.3155424720409674 0.9718051214293305 1.664638107859294 1.5030144067657185 1.0 15.263426976574133 -6.311241007364532 0.9838618680182546 1.3508144081815625 0.5816575410513762 0.4885158456389155 0.2793434044029558 0.4344261410209924 0.894069863895283 0.13242061264652805 0.19620910199884264 4.883812618480791e-07 6.311241007364532 -0.7691568671301863 IDGATQSS(ph)PAEPKSEDADR ddPTM_PC-9_Lapatinib_30min_R1 4 IDGATQSSPAEPKSEDADR 19 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 IDGAT(0.041)QS(0.194)S(0.763)PAEPKS(0.002)EDADR;IDGATQS(0.001)S(0.999)PAEPKSEDADR;IDGAT(0.035)QS(0.082)S(0.685)PAEPKS(0.198)EDADR;IDGAT(0.023)QS(0.085)S(0.446)PAEPKS(0.446)EDADR 175.77 5.6303e-09 101062000.0 323098.0 88881.0 152769.0 120318.0 97561.0 93085.0 53654.3 52662.4 127943.0 60196.7 True False 318490.563271083 88675.20150533225 140208.92252539351 129166.58708908217 91822.65379230588 89103.97154173329 56432.25712149387 55109.2873575431 113532.71204048142 70601.61938793914 4.511094306789947 1.2559938748441883 1.9859165234578937 1.8295130934510502 1.3005743294323349 1.262066965519985 0.7993054211888826 0.7805669025058852 1.60807518332754 1.0 16.107413654492863 -3.3278633151387846 1.4909680288504836 1.269615108023551 199.99999998452856 0.8372823459127027 0.4164782808789697 35.162257354754566 1.6224205137967231 0.12412611787829485 22764.048731873532 0.0004700420209592906 3.3278633151387846 198.730384876505 IDGATQSSPAEPKS(ph)EDADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IDGATQSSPAEPKSEDADR 19 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 IDGAT(0.014)QS(0.04)S(0.099)PAEPKS(0.847)EDADR 54.073 0.016232 16466000.0 12669.0 2762.4 6219.7 13049.0 19053.0 21331.0 13970.0 25629.0 20634.0 16949.0 True False 14813.611475844169 3036.632815934403 6368.001236343604 12317.906835428796 15319.701423104918 20212.364808920618 12646.660465958634 24956.265906170127 20935.733214307173 20021.71953178982 0.7398770845992328 0.15166693405693446 0.31805466190017817 0.6152272194139387 0.7651541316808882 1.009521923270781 0.6316470693677777 1.246459669287915 1.0456511080911963 1.0 14.289278262487333 -6.32600073433131 1.3469106416021381 0.9994279320924881 0.3762321945912923 0.6175874786806737 0.19949945775945116 0.27862453907469326 1.0257523066766452 0.07957438048615018 0.10586463380064878 4.720622430715966e-07 6.32600073433131 -0.6231957375011958 IDGPPT(ph)PASLR ddPTM_PC-9_AZD4547_30min_R2 1 IDGPPTPASLR 11 0 E9PQ01;O94913 E9PQ01 PCF11 Pre-mRNA cleavage complex 2 protein Pcf11 1 IDGPPT(0.987)PAS(0.013)LR 96.334 0.014297999999999998 3043600.0 23592.0 21376.0 26567.0 36029.0 27458.0 25625.0 23853.0 30565.0 26615.0 28706.0 True False 31093.765255915685 28285.3739695369 26214.70422143057 27723.070692501104 23645.93065958014 24022.664699123692 25975.87079061611 25841.881563826926 28021.814564400618 27701.0116774264 1.1224776054390118 1.0210953411707595 0.9463446507548667 1.0007963252509178 0.853612529929701 0.8672125400640079 0.9377228201302081 0.9328858405877472 1.0115809086942353 1.0 14.757651045908878 -4.663368244250338 1.1790059557040702 0.9327227786567313 1.2513959517795876 0.5485771881967288 0.05051347998720156 1.481191587207424 1.4600312759114156 0.016041282815594835 0.6219304168575195 2.1708596965410562e-05 4.663368244250338 0.31867317312285637 IDGPPT(ph)PASLR ddPTM_PC-9_Lapatinib_30min_R1 1 IDGPPTPASLR 11 0 E9PQ01;O94913 E9PQ01 PCF11 Pre-mRNA cleavage complex 2 protein Pcf11 1 IDGPPT(1)PASLR 97.779 0.008847399999999998 0.0 28185.0 22222.0 30234.0 21840.0 22389.0 22448.0 25590.0 17861.0 27561.0 20663.0 True False 27783.07673150403 22170.5463243156 27748.277226615017 23446.18645610423 21072.123038467587 21487.95136884383 26914.92498716836 18690.887264786215 24456.78994980353 24234.572018283165 1.1464232465315989 0.9148313536376705 1.1449873018463468 0.9674685584880907 0.8695067122526551 0.8866651885840107 1.110600383900449 0.7712489104691159 1.0091694597021443 1.0 14.56477898433342 -5.982256375068738 23.1710488118828 0.9339573449166645 1.0538345547977699 0.22376605595198107 0.10501861907752746 154.77533621848536 202113.79606920702 0.028024001229501008 0.04155213619357373 1.041702304507681e-06 5.982256375068738 0.1198772098811054 IDHYLGK ddPTM_PC-9_AZD4547_30min_R2 1 IDHYLGK 7 0 P11413;P11413-2;P11413-3;E7EUI8;E7EM57;E9PD92 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 68.915 0.040199 15102000.0 163800.0 177970.0 195130.0 243580.0 219430.0 205710.0 212690.0 237910.0 198490.0 214700.0 False True 215884.99274834653 235495.32210696506 192542.44870432277 187426.39427348564 188965.93213750696 192846.9211807504 231618.99796487365 201146.4761279266 208981.77617463382 207183.41834959402 1.041999376533453 1.1366513979878377 0.929333294324903 0.9046399357946152 0.9120707325074272 0.9308028736901487 1.1179417726086935 0.9708618466199795 1.0086800277713601 1.0 17.660549017895264 -5.263387338705373 24.997668065633977 0.9699753067703814 1.0893253896429667 0.3580450407940625 0.06291407664166027 182.4322976275883 2341140.0792809203 0.017560357946758275 0.03982226956073122 5.452713273877749e-06 5.263387338705373 0.1193500828725853 IDHYLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IDHYLGK 7 0 P11413;P11413-2;P11413-3;E7EUI8;E7EM57;E9PD92 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ; 77.282 0.025196 29020000.0 219560.0 233568.0 232159.0 262550.0 287712.0 228333.0 254485.0 208622.0 201947.0 182438.0 False True 256727.17149233192 256755.08744286397 237694.55102791073 247840.17469858422 231336.8989578731 216358.81552272593 230378.3384881524 203145.89355328027 204900.09282881173 215512.56522158658 1.1912399224999672 1.1913694553209577 1.1029266473790842 1.1500033626520054 1.0734265016984796 1.0039266865960657 1.0689786846130342 0.9426173984074149 0.9507570596551376 1.0 17.717412460940977 -6.412350987561867 0.6136302748814041 0.9628380153338135 1.2021642068035645 0.8354210332935769 0.03550059732833485 0.341260890669847 0.27821581021664943 0.026029957341907196 0.04242388560145731 3.869447979659763e-07 6.412350987561867 0.23932619146975098 IDHYLGK ddPTM_PC-9_Lapatinib_30min_R1 1 IDHYLGK 7 0 P11413;P11413-2;P11413-3;E7EUI8;E7EM57;E9PD92 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 78.49600000000001 0.023706 24795000.0 442660.0 527300.0 540290.0 548570.0 526950.0 511370.0 522690.0 480970.0 506470.0 457420.0 False True 436347.5872260986 526079.0692472162 495869.44177971187 588913.6677758752 495955.83702356037 489499.89716169296 549752.3306581874 503317.62206730904 449426.0152344609 536484.437526162 0.8133462160397147 0.9806045291324255 0.9242941772295686 1.097727401919569 0.924455216838186 0.9124214290704792 1.024731179888845 0.938177488219804 0.8377242354071908 1.0 19.033176795969453 -4.756709193218666 24.965520380409615 0.9606941874898907 0.813345988775648 0.29883137911758806 0.06739236278019585 184.95429106565865 976054.6636546348 0.016637189285961976 0.13157241893047433 1.7510187912260737e-05 4.756709193218666 -0.14734819871424265 IDIIPNPQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IDIIPNPQER 10 0 P08238;Q58FF7 P08238 HSP90AB1;HSP90AB3P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 95.775 0.026663 5327300.0 26327.0 25505.0 19410.0 33819.0 21732.0 33916.0 25846.0 26921.0 21015.0 23933.0 False True 30783.641118047955 28036.967843327173 19872.80801283491 31924.231072677332 17473.77060446732 32137.3852542943 23397.67977116441 26214.35227515728 21322.304618525995 28271.86344647624 1.088843725364158 0.9916915415358536 0.702918222934181 1.1291873679680042 0.6180622171420832 1.1367268137502218 0.8275959529678848 0.9272240694281011 0.7541881580919836 1.0 14.787079356329796 -5.006924993734211 22.483608867830213 0.8873704919630692 1.0645561879390504 0.1367423069255811 0.16228915280155204 152.02342390926705 493637.7787421272 0.03698417099853694 0.12330629624469124 9.841810673321913e-06 5.006924993734211 0.17718569597598122 IDIIPNPQER ddPTM_PC-9_Lapatinib_30min_R1 1 IDIIPNPQER 10 0 P08238;Q58FF7 P08238 HSP90AB1;HSP90AB3P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 107.21 0.010162000000000001 22385000.0 43081.0 47766.0 72798.0 57042.0 48351.0 54893.0 48822.0 65491.0 64070.0 43296.0 False True 42466.65703991217 47655.40076173429 66812.82944840653 61237.058966533754 45507.089241723465 52545.35435183292 51349.76427211931 68533.9509466498 56853.76191298979 50779.65591170632 0.8362927293905168 0.9384742749063844 1.3157400980537965 1.2059368632392933 0.8961677353790938 1.0347717685050233 1.0112271016842704 1.3496340161464258 1.1196169192608332 1.0 15.63196299871453 IDILDSALLRPGR ddPTM_PC-9_AZD4547_30min_R2 1 IDILDSALLRPGR 13 1 P62195-2;P62195 P62195-2 PSMC5 26S protease regulatory subunit 8 0 92.11200000000001 0.018269 0.0 9329.8 6597.7 9907.0 12860.0 11533.0 9421.4 9599.7 10804.0 10147.0 10022.0 False True 12296.482328104528 8730.277499944497 9775.626706881192 9895.325685019397 9931.842024070855 8832.278368637033 10454.054702916932 9134.490051221535 10683.34970448893 9671.132830459383 1.2714624588110885 0.9027150855014991 1.0108047193905458 1.0231816539479135 1.0269574617763872 0.9132620266386617 1.080954515482584 0.9445108666538338 1.1046637339983125 1.0 13.239469174691342 -4.748279490923293 24.999993927271834 1.0006506740599643 1.2714631091258906 0.628656569437114 0.06241033883051197 399.95648165623913 759757.3634461341 0.014376650650165966 0.26756303804878256 1.785338247720188e-05 4.748279490923293 0.2708124350659262 IDILDSALLRPGR ddPTM_PC-9_Lapatinib_30min_R1 1 IDILDSALLRPGR 13 1 P62195-2;P62195 P62195-2 PSMC5 26S protease regulatory subunit 8 0 139.46 4.8316e-05 0.0 7188.1 5455.0 7920.0 7503.4 6192.1 7686.4 5327.3 9202.2 7374.1 7911.0 False True 7085.596375863903 5442.369282654203 7268.848172084107 8055.225066608628 5827.892852136998 7357.670589873539 5603.121527320907 9629.767806282722 6543.551205284499 9278.405809255104 0.7636652806019867 0.586562971542536 0.7834156342713006 0.8681690833756843 0.6281135975238054 0.7929886600276037 0.6038883879956897 1.037868789558346 0.7052452048128118 1.0 13.17966123132371 -9.240336122834057 0.3206769746716676 1.053912299415321 0.7007357017637712 0.27908177174382165 0.12597098584870486 4.974347199013116 0.9013072022257461 0.5176117105690997 0.13716794821609934 5.749947470764776e-10 9.240336122834057 -0.35317659765154974 IDIS(ph)PSTFR ddPTM_PC-9_AZD4547_30min_R2 8 IDISPSTFR 9 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 IDIS(0.912)PS(0.082)T(0.005)FR;IDIS(0.95)PS(0.044)T(0.006)FR;IDIS(0.994)PS(0.006)TFR;IDIS(0.99)PS(0.01)TFR;IDIS(0.996)PS(0.004)TFR;IDIS(0.849)PS(0.15)T(0.002)FR;IDIS(0.937)PS(0.031)T(0.033)FR;IDIS(0.963)PS(0.029)T(0.008)FR 166.86 0.0010934 2553868300.0 2127186.0 2016611.6 2071335.0 2863945.0 2473186.0 2171100.0 1955814.0 2498380.0 1717643.0 1937366.0 True False 2803586.8997825626 2668441.8627108084 2043867.7445137554 2203706.7277591685 2129826.8141978392 2035340.7737860489 2129877.6570862443 2112312.7780609797 1808434.102342317 1869539.4060283122 1.4996136966904379 1.4273258183841662 1.0932466777235736 1.178743128202239 1.139225419549988 1.0886856769229425 1.139252614958783 1.1298573173958502 0.9673153165485779 1.0 20.834251449871672 -5.210975657428995 3.862837878695934 1.1016486705518493 1.4840559138705973 0.8492468587744678 0.06270176654785065 0.07869375600256663 2.4448280385193097 0.016210377731775985 0.04707082723021249 6.152113548573893e-06 5.210975657428995 0.382407243318748 IDIS(ph)PSTFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 IDISPSTFR 9 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 IDIS(0.987)PS(0.013)TFR;IDIS(0.991)PS(0.008)TFR;IDIS(0.947)PS(0.053)T(0.001)FR;IDIS(0.959)PS(0.036)T(0.004)FR;IDIS(0.993)PS(0.007)TFR;IDIS(0.997)PS(0.003)TFR;IDIS(0.978)PS(0.022)TFR 144.55 0.00054254 1737418800.0 298824.0 382232.0 348369.0 362657.0 388736.0 315966.0 356782.0 296356.0 293982.0 265363.0 True False 349409.00115696975 420177.46687671484 356675.4381567903 342338.5040398579 312565.97136472556 299396.18673364626 322985.0260820076 288576.9690151381 298280.93059069716 313471.2112876471 1.1146446262854597 1.340402090357038 1.1378251823881147 1.092089135182885 0.9971122071490933 0.9550994667223673 1.0303498836632576 0.9205852359766922 0.9515417041502703 1.0 18.257973428661366 -5.922865332039064 1.5785630457241042 0.9698870873797479 1.2280763533655747 0.7363507430825538 0.06053074668372193 0.1783025965091218 0.9028241004497951 0.01939099234413721 0.035875721068862845 1.1943583990045642e-06 5.922865332039064 0.2581892659858268 IDIS(ph)PSTFR ddPTM_PC-9_Lapatinib_30min_R1 8 IDISPSTFR 9 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 IDIS(0.978)PS(0.011)T(0.011)FR;IDIS(0.941)PS(0.051)T(0.008)FR;IDIS(0.995)PS(0.005)TFR;IDIS(0.999)PS(0.001)TFR;IDIS(0.981)PS(0.009)T(0.01)FR;IDIS(0.624)PS(0.367)T(0.009)FR;IDIS(0.938)PS(0.051)T(0.011)FR;IDIS(0.665)PS(0.334)TFR 128.51 0.0013277 2351750500.0 328822.0 399913.0 421866.0 370402.0 433237.0 401265.0 373455.0 384007.0 372558.0 312864.0 True False 324132.9379814305 398987.02601908153 387181.80592985306 397642.5987048499 407754.8514367141 384103.8313444013 392790.6725706511 401849.3671064757 330596.59483033617 366942.1255349242 0.8833353148235925 1.0873295766667364 1.055157691053933 1.0836657092046078 1.1112238771776164 1.0467695165401327 1.0704431168758428 1.0951301012950314 0.9009502366303571 1.0 18.485193012197712 -10.299262771538976 7.171370230068894 0.99999999992949 1.045639264989257 0.010000475259121178 0.07610477837831099 0.0 1.473333392405674e-10 0.07090601143282471 0.017197233545434766 5.020387371481648e-11 10.299262771538976 0.04563926505976701 IDIS(ph)PSTFRK ddPTM_PC-9_AZD4547_30min_R2 1 IDISPSTFRK 10 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 IDIS(0.995)PS(0.005)TFRK 78.692 0.0091904 217800000.0 67763.0 36807.0 94025.0 192710.0 151460.0 92765.0 69961.0 93247.0 59274.0 106660.0 True False 89310.22444204024 48704.142949885165 92778.16706515636 148283.6868398203 130432.39338990477 86964.38988543254 76187.39346758471 78837.81875289293 62407.10262973066 102925.86586477708 0.8677140939418968 0.4731963393329346 0.9014076907261324 1.440684376021027 1.267246015314221 0.8449225970047747 0.7402162015103075 0.7659670199565698 0.6063306060667049 1.0 16.65124605983212 -10.791674472799558 5.304430880554342 1.0000149486851213 0.8869616193967488 0.016791422218323082 0.2719744348264955 5.3927261941091255e-05 7.433617950651105e-06 0.29535915355867537 0.07162564747053805 1.6155690594798138e-11 10.791674472799558 -0.11305332928837253 IDIS(ph)PSTFRK ddPTM_PC-9_Lapatinib_30min_R1 1 IDISPSTFRK 10 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 IDIS(0.997)PS(0.002)T(0.001)FRK 61.375 0.029399 133840000.0 90164.0 33687.0 49435.0 41421.0 30556.0 34393.0 23911.0 20838.0 44400.0 22778.0 True False 88878.24482594727 33608.99982122312 45370.64512461839 44467.23851640536 28758.75615540739 32922.091563998845 25148.99458257845 21806.209552859043 39399.20444727246 26715.14695022281 3.326885867090692 1.258050344392465 1.698311643546471 1.6644953740759603 1.0764962741545967 1.2323380300075149 0.9413758655132047 0.8162489090361217 1.4747889847165472 1.0 14.705370332468124 -2.9408740719403794 1.247941066860834 1.1893916768631891 199.9999999997833 0.8085257330803505 0.3005472684965415 61.76147345790993 1.3254067547608517 0.0914247372949967 34010.072293758596 0.001145845142621724 2.9408740719403794 198.81060832292013 up IDIS(ph)PSTLR ddPTM_PC-9_AZD4547_30min_R2 5 IDISPSTLR 9 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 IDIS(0.988)PS(0.012)TLR;IDIS(0.5)PS(0.5)TLR;IDIS(0.917)PS(0.083)TLR;IDIS(0.975)PS(0.019)T(0.006)LR;IDIS(0.955)PS(0.045)TLR 160.91 0.0001467 1119153900.0 159120.0 163471.0 226056.0 252022.0 230794.0 208906.0 196043.0 247962.0 203663.0 171281.0 True False 209716.85009839412 216309.80390036324 223058.34973763363 193922.22160108556 198752.2368944256 195843.07479551728 213490.4472143864 209645.17049990653 214428.21039374493 165284.5043238787 1.2688234202974602 1.308711937547995 1.3495418136750785 1.1732631706423646 1.2024856032781277 1.1848846665732098 1.2916543392116606 1.2683897462589844 1.2973279695570736 1.0 17.33459195053107 -10.570612057132863 4.308454887318598 0.9999807022649629 1.259240567006224 0.6749441896102228 0.054240770299364686 8372070.48377206 6846840.619479581 1392.157419107188 0.014330499209348514 2.6877442589023826e-11 10.570612057132863 0.25925986474126117 IDIS(ph)PSTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 IDISPSTLR 9 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 IDIS(0.982)PS(0.017)TLR;IDIS(0.372)PS(0.256)T(0.372)LR;IDIS(0.618)PS(0.376)T(0.006)LR;IDIS(1)PSTLR;IDIS(0.984)PS(0.016)TLR;IDIS(0.494)PS(0.494)T(0.012)LR;IDIS(1)PSTLR 152.69 8.954899999999999e-05 1104555530.0 212113.6 279940.8 285592.2 266172.2 320319.0 224507.5 268159.9 214799.1 205552.8 190663.8 True False 248020.2430454358 307731.47255970543 292401.8011624501 251259.43457591598 257554.7913791813 212733.93147713415 242757.85296244966 209160.8512234588 208558.62083230828 225229.63764618913 1.1011883055774756 1.366300970759086 1.2982385631760462 1.1155700342182178 1.1435208708357085 0.9445201515233783 1.0778237513474822 0.9286559859942917 0.9259821354413882 1.0 17.781037156525556 -6.382283533281564 1.2456798290635924 0.9695723844449503 1.262327534273322 0.6672860879553796 0.08272703144482876 0.25766469634988504 0.8238328261431683 0.034352414655919004 0.0441615904200702 4.1468322435521814e-07 6.382283533281564 0.2927551498283717 IDIS(ph)PSTLR ddPTM_PC-9_Lapatinib_30min_R1 6 IDISPSTLR 9 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 IDIS(0.609)PS(0.387)T(0.004)LR;IDIS(0.902)PS(0.082)T(0.016)LR;IDIS(0.869)PS(0.128)T(0.003)LR;IDIS(0.942)PS(0.057)TLR;IDIS(0.617)PS(0.377)T(0.006)LR;IDIS(0.991)PS(0.008)TLR 117.02 0.0018832 1568565300.0 201557.0 241979.0 246827.0 218882.0 252064.0 260973.0 203455.0 251867.0 237354.0 200486.0 True False 198682.76021897272 241418.71249264598 226533.83683977352 234979.31244894702 237238.09109689138 249811.79314777633 213988.90438703928 263569.6603056891 210620.69307157426 235139.7379691974 0.8449561181572788 1.026703162033255 0.963400907036176 0.9993177439014098 1.008923855856167 1.0623971741454477 0.9100499398152395 1.120906498331711 0.8957256433583547 1.0 17.843158845527007 -4.755621231598359 24.986352154938245 1.0008522185317918 0.8449558645045674 0.3484854907161461 0.06295758320548982 196.20299845894874 842519.135097373 0.01410101574779109 0.12323140022896933 1.7554108097688995e-05 4.755621231598359 -0.15589635402722446 IDIS(ph)PSTLRK ddPTM_PC-9_AZD4547_30min_R2 1 IDISPSTLRK 10 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 IDIS(0.967)PS(0.016)T(0.016)LRK 61.233000000000004 0.029684 323170000.0 94211.0 53983.0 106420.0 188290.0 164310.0 121880.0 89565.0 123080.0 94425.0 108480.0 True False 124168.13828946563 71431.9490548985 105008.80126640717 144882.64955150092 141498.39269705064 114258.82433284649 97536.11148960442 104060.8140970334 99416.11272754178 104682.14821874216 1.1861443465031483 0.6823699195170836 1.0031204274389023 1.3840244207518213 1.3516955383966505 1.0914833739759815 0.9317358608823588 0.9940645646628264 0.9496949997606415 1.0 16.67565591028547 -7.187082147424412 6.13492371474388 0.9687045872625055 1.1155074862214172 0.1349832340732352 0.1835129489262778 0.5837219265072191 38.304728372592336 0.08015255305608618 0.06166434684389999 6.500067290088272e-08 7.187082147424412 0.14680289895891163 IDIS(ph)PSTLRK ddPTM_PC-9_Lapatinib_30min_R1 1 IDISPSTLRK 10 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 IDIS(0.993)PS(0.007)TLRK 69.815 0.017144 255480000.0 122390.0 57133.0 78735.0 61886.0 60749.0 66368.0 42619.0 47787.0 68218.0 47915.0 True False 120644.69615642309 57000.71204874107 72261.71222588926 66437.30288564412 57175.8632571293 63529.5953513643 44825.60328363142 50007.35847502036 60534.5704726134 56197.043907275714 2.146815700047943 1.0143008970861778 1.2858632269896617 1.1822205985650185 1.0174176305691207 1.1304793087726677 0.7976505553849593 0.8898574550919752 1.0771842478493092 1.0 15.778206622940859 -3.0444041406673374 1.5205693881234428 1.0284872231030322 199.99999999999312 0.8355532582158033 0.14445654815933048 99.47347239188143 1.6822551580025922 0.04261010681043156 67821.56741459649 0.0009028089573289554 3.0444041406673374 198.97151277689008 up IDISPS(ph)TFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IDISPSTFR 9 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 IDIS(0.025)PS(0.972)T(0.003)FR 137.46 0.00094373 278960000.0 46935.0 56988.0 54148.0 56244.0 72237.0 53800.0 55256.0 51204.0 45606.0 45943.0 True False 54880.168491494645 62645.392019428706 55439.09367743357 53092.83102550829 58082.67840764341 50978.63329051284 50021.751661203336 49859.94925512253 46272.90147192461 54272.10221541212 1.0112040302708203 1.154283498560311 1.0215026028914365 0.9782711348599845 1.0702124302667821 0.9393156190665486 0.9216844312140581 0.9187031130141734 0.8526093440836736 1.0 15.727923171719915 -6.838192568425604 5.004231919702099 0.918607240489694 1.0477699870899466 0.5488098379990829 0.054649985148568135 0.15833440499143184 7.124970076477417 0.019687959047093737 0.017494680211320203 1.4514678864929966e-07 6.838192568425604 0.12916274660025262 IDISPS(ph)TLR ddPTM_PC-9_AZD4547_30min_R2 1 IDISPSTLR 9 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 IDIS(0.396)PS(0.601)T(0.004)LR 96.171 0.0051903999999999995 606870000.0 30262.0 25624.0 38167.0 45772.0 41289.0 39883.0 32839.0 41294.0 31980.0 38177.0 True False 39884.68651129706 33906.45689536927 37660.880642125216 35219.972570350576 35556.735050018346 37389.1097051766 35761.60738242748 34912.96114171995 33670.39751153602 36840.43485017444 1.08263343452658 0.9203598446452302 1.0222702526527558 0.9560140295190845 0.9651551398517215 1.0148932784651852 0.9707162124406398 0.9476804843294252 0.9139522279926778 1.0 15.16900247009074 -7.5810525194458975 4.248665045179015 0.9486894110323426 0.9888759435995267 0.12604458221523795 0.045587647105517326 0.4279833354138327 15.886629615260187 0.021130894079556498 0.011875744437091725 2.623901214529438e-08 7.5810525194458975 0.040186532567184075 IDISPST(ph)FR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IDISPSTFR 9 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 IDIS(0.137)PS(0.33)T(0.533)FR 102.06 0.008064 3809400.0 8956.0 10052.0 7648.5 9918.0 11514.0 6790.2 11175.0 7501.5 6515.2 6127.3 True False 10472.073910936966 11049.896128646325 7830.869247097776 9362.326614589843 9257.914353940585 6434.109958536067 10116.423100006275 7304.593573496249 6610.472474452562 7238.130986319889 1.44679253950077 1.526622846357809 1.0818910657873095 1.2934729465776036 1.2790476397067279 0.8889186960966268 1.3976568148775388 1.0091822857726633 0.9132844496661354 1.0 12.821401500635073 -1.5228787452858477 0.22968615214106491 0.9671721865236338 4.029975604082365 0.4797345657130151 0.159391399912023 44.01560399290046 0.5757203057261581 0.23007767447332625 50.65898378873697 0.029999999999619376 1.5228787452858477 3.0628034175587313 IDISPST(ph)LR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IDISPSTLR 9 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 IDIS(0.004)PS(0.034)T(0.961)LR 103.08 0.007261399999999999 458580000.0 34140.0 47543.0 52549.0 44821.0 47326.0 37471.0 40454.0 37286.0 41948.0 31353.0 True False 39919.22770426396 52262.7548392591 53801.96745319225 42309.82468164259 38052.8100325336 35505.954796074475 36621.904258403054 36307.28200778259 42561.410142180735 37037.05070978855 1.0778187501229324 1.4110938597345317 1.4526525849687295 1.1423648446840422 1.0274254915896042 0.9586604255908147 0.9887910499505357 0.9802962523197591 1.149157649610911 1.0 15.176681599752099 -5.989824374254665 4.2348095198635205 1.0155792350747659 1.323498755497299 0.6153636981721804 0.10456100379070057 0.1305141158458314 5.6120818227995635 0.030991037467623526 0.04492789233714858 1.0237068887149496e-06 5.989824374254665 0.3079195204225331 IDISPSTFR ddPTM_PC-9_AZD4547_30min_R2 1 IDISPSTFR 9 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 0 104.06 0.006181399999999999 0.0 5694.7 7706.5 9781.4 11253.0 12101.0 10408.0 10421.0 9609.0 8278.3 8089.5 False True 7505.496142881611 10197.475416178711 9651.692244946773 8658.794707116898 10420.985028464534 9757.186114672373 11348.448811848004 8124.149842853362 8715.874037515596 7806.289067252168 0.9614678726627739 1.306315373197965 1.2363995442387827 1.1092075418320135 1.334947365987402 1.249913503152776 1.4537571839935315 1.040718550499832 1.116519509132603 1.0 12.930421171493482 IDISPSTLR ddPTM_PC-9_AZD4547_30min_R2 1 IDISPSTLR 9 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 0 93.14299999999999 0.019118 0.0 7215.1 6501.1 9395.3 14648.0 10133.0 7549.8 7120.8 13384.0 8160.0 7533.5 False True 9509.351716597042 8602.453439060455 9270.71218322004 11271.129909344027 8726.2078583118 7077.70981250514 7754.537405182542 11315.810333723537 8591.320941029835 7269.7544580189415 1.308070550595791 1.1833210445741358 1.2752441965896015 1.550414112943161 1.2003442356552099 0.9735830630012592 1.0666849134950986 1.556560183575605 1.1817897001394775 1.0 12.82769092140933 -6.4961423205898505 24.956806612094542 1.1740569710836732 1.3225295862842714 0.17930963299820835 0.17382123742190775 1575.880497918756 1470988.6505046093 0.057543056624506705 0.0650511452769324 3.19049214268275e-07 6.4961423205898505 0.14847261520059818 IDKAAT(ph)DDS(ph)VRK ddPTM_PC-9_Lapatinib_30min_R1 1 IDKAATDDSVRK 12 2 A0A590UK68;A0A1W2PQI5 A0A590UK68 2 IDKAAT(1)DDS(1)VRK 74.376 0.037037 0.0 21162.0 19593.0 19440.0 17737.0 15923.0 17835.0 15545.0 18704.0 18220.0 11972.0 True False 20860.225999364495 19547.633612290334 17841.718240570088 19041.43814889748 14986.440445822484 17072.23862541562 16349.844037730843 19573.05612230901 16167.87173489424 14041.344248312746 1.4856288422578292 1.3921483062164253 1.2706559945436853 1.3560979498943317 1.067308099623247 1.2158550010243554 1.1644073208799433 1.3939588529539098 1.1514475714700196 1.0 13.777393438236095 -1.5228787452803394 0.3780856721317626 1.1681556498762067 5.818755385077986 0.5046733810207624 0.104913768505501 61.07991188853581 0.8358343555340103 0.08101292234565852 207.77216577683743 0.029999999999999874 1.5228787452803394 4.650599735201779 IDLPEVQIEHDPELEKES(ph)PGLK ddPTM_PC-9_AZD4547_30min_R2 2 IDLPEVQIEHDPELEKESPGLK 22 1 Q14966-3;Q14966;Q14966-5 Q14966-3 ZNF638 Zinc finger protein 638 1 IDLPEVQIEHDPELEKES(1)PGLK;IDLPEVQIEHDPELEKES(1)PGLK 78.794 0.00026292 10856000.0 115254.0 105065.0 108112.0 124134.0 119875.0 126820.0 115597.0 108164.0 110083.0 128775.0 True False 151902.37456787497 139025.20659194404 106678.3642408741 95516.82415118175 103232.42544311902 118889.92535191652 125884.90905893841 91449.73916145174 115901.76264110129 124266.62644605937 1.2223907489257504 1.1187654366097317 0.8584635094055616 0.7686442199558938 0.8307333062423586 0.9567325415687797 1.0130226647263294 0.7359155211407263 0.9326861600400086 1.0 16.92307936675978 -5.1443027015230545 3.543764733247079 0.8781571922551 1.2034006898404024 0.627540141081397 0.0885303271566732 0.15066420861733865 3.3794873469754316 0.023669641705074632 0.07719686485709405 7.172941658240032e-06 5.1443027015230545 0.32524349758530235 IDLPEVQIEHDPELEKES(ph)PGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IDLPEVQIEHDPELEKESPGLK 22 1 Q14966-3;Q14966;Q14966-5 Q14966-3 ZNF638 Zinc finger protein 638 1 IDLPEVQIEHDPELEKES(1)PGLK 104.03 1.9415e-05 3781500.0 33395.0 32827.0 26883.0 36887.0 39477.0 32038.0 32879.0 37579.0 31389.0 26604.0 True False 39048.113918684656 36085.84761391494 27523.992674345252 34820.34097926753 31741.765238015676 30357.870880324357 29764.46309665384 36592.59106824175 31848.004742846162 31427.09460285187 1.2424983732075956 1.1482400161369137 0.8758045572512952 1.107972003753339 1.010012717979194 0.965977646485002 0.9470956024663141 1.1643644291865636 1.0133932247098685 1.0 14.93972128242726 -5.032750995026518 7.7070076033529915 1.0155743485742672 1.2202401463950305 0.500963092396483 0.07625408404868536 0.16261958377790986 34.74990760953019 0.0191940173623754 0.05441401476523431 9.273613783928462e-06 5.032750995026518 0.20466579782076333 IDLPEVQIEHDPELEKES(ph)PGLK ddPTM_PC-9_Lapatinib_30min_R1 2 IDLPEVQIEHDPELEKESPGLK 22 1 Q14966-3;Q14966;Q14966-5 Q14966-3 ZNF638 Zinc finger protein 638 1 IDLPEVQIEHDPELEKES(1)PGLK;IDLPEVQIEHDPELEKES(1)PGLK 91.62200000000001 8.3207e-05 12073600.0 62456.0 56600.0 54976.0 59462.0 61457.0 52288.0 49572.0 53015.0 53565.0 47523.0 True False 61565.365986972334 56468.94617749366 50456.08549349693 63835.03383941712 57842.22008911086 50051.76412928128 52138.59560234118 55478.270440772685 47531.94563554391 55737.28722958288 1.104563373050136 1.0131269206715616 0.9052483176238452 1.145284189675028 1.0377652548976366 0.8979942623170225 0.9354347546119598 0.9953528992585646 0.8527854152599673 1.0 15.766355166783645 -6.747671825966986 24.77364754394705 0.9359681077924694 1.037868009284404 0.35358755603095116 0.07083425774474542 253.29448468089774 455782.70599520457 0.023449030028706217 0.02332605424777 1.7878380419268424e-07 6.747671825966986 0.10189990149193451 IDLQVPSS(ph)ESK ddPTM_PC-9_AZD4547_30min_R2 1 IDLQVPSSESK 11 0 Q92541 Q92541 RTF1 RNA polymerase-associated protein RTF1 homolog 1 IDLQVPS(0.011)S(0.969)ES(0.021)K 102.33 0.008371799999999999 0.0 35087.0 36867.0 31773.0 49234.0 45182.0 49074.0 41705.0 37033.0 37492.0 45875.0 True False 46243.93614506247 48783.53677652123 31351.669259890597 37883.861957717345 38909.259198089814 46005.395022235934 45416.66420670966 31310.400783680787 39473.75057856501 44268.93021326328 1.0446138165590337 1.1019813792994109 0.7082093266960723 0.8557663755418032 0.8789292854073155 1.0392253619097485 1.0259264000263217 0.7072771045707351 0.891680697690282 1.0 15.434006889767065 -5.222963023610117 24.991456451318705 0.8867202454592358 1.073297709703138 0.30913860700421736 0.11055471602830275 687.1548820499405 446324.01680550916 0.029285285895965088 0.07747883805677278 5.98462546760981e-06 5.222963023610117 0.1865774642439022 IDRDSYS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 IDRDSYSPR 9 1 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 IDRDS(0.001)YS(0.999)PR 129.0 0.0063323 42195000.0 159740.0 148310.0 178260.0 254900.0 226890.0 193580.0 156920.0 216930.0 177830.0 184330.0 True False 210533.9972015923 196248.30713987735 175896.15592698508 196136.74316574226 195390.23990648068 181475.41199829683 170885.5760056794 183408.45305548795 187229.73075285982 177876.6628056851 1.1835953850313827 1.1032830504261353 0.9888658419409209 1.1026558519371634 1.0984591054529038 1.0202317107587242 0.9606969981911407 1.031099021999563 1.0525817597409737 1.0 17.440517717683598 -6.799227438131667 6.194251276920979 1.0109645244383112 1.0903535000562865 0.41081774852713904 0.04920808423129122 0.2150826509382787 21.946838949063803 0.018297047510203106 0.016414853136278877 1.5877150513703653e-07 6.799227438131667 0.07938897561797531 IDRDSYS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 IDRDSYSPR 9 1 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 IDRDS(0.019)YS(0.981)PR 60.691 0.032542 20453000.0 58790.0 36917.0 64757.0 43458.0 43876.0 51717.0 40136.0 36015.0 59952.0 33167.0 True False 57951.643819234436 36831.52095467372 59432.929429248805 46654.04629163818 41295.29994353494 49505.184468215266 42214.045693043736 37688.38837922151 53199.57443745222 38899.87175775047 1.489764392544252 0.9468288529083736 1.5278438396755716 1.1993367634262895 1.061579333749531 1.2726310455856908 1.0851975542729893 0.9688563657465636 1.3676028231854684 1.0 15.247477778597359 -5.994051898983153 24.986383797059073 1.129781911124172 1.2972767183296219 0.1803202613226309 0.1842201948827482 295.04998549191737 1239407.7476531945 0.04903648549178228 0.07250690102512763 1.0137902287151343e-06 5.994051898983153 0.16749480720544985 IDS(ph)LSAQLSQLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IDSLSAQLSQLQK 13 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 IDS(0.997)LS(0.003)AQLSQLQK;IDS(1)LSAQLSQLQK 159.34 0.00023208 9531500.0 34650.0 40802.0 39799.0 45850.0 47760.0 37501.0 43465.0 41847.0 39662.0 27161.0 True False 40515.56063130477 44852.5529089761 40747.959098548 43281.17314770561 38401.77084802868 35534.3815432625 39347.68054065082 40748.56059056155 40241.98171686787 32085.0742936423 1.2627541473180561 1.3979257924879946 1.2699973428648805 1.3489503795938484 1.1968733653715753 1.1075050416917278 1.2263546651175314 1.2700160896506303 1.2542274750113909 1.0 14.96961470336715 -6.273128337181013 20.208568213502804 1.1884401423024789 1.3219146805855115 0.42073665188181575 0.08200939872484546 60.10658506295835 103915.15901747238 0.02482208639111035 0.028514723540694238 5.33177314427714e-07 6.273128337181013 0.13347453828303268 IDS(ph)LSLNGEFGYQK ddPTM_PC-9_AZD4547_30min_R2 1 IDSLSLNGEFGYQK 14 0 Q8TEQ0-2;Q8TEQ0 Q8TEQ0-2 SNX29 Sorting nexin-29 1 IDS(0.628)LS(0.372)LNGEFGYQK 94.09 0.0035321 7962400.0 21816.0 20128.0 29584.0 28659.0 33194.0 27778.0 25199.0 29705.0 22384.0 28436.0 True False 28753.034199010548 26633.982375507043 29191.69683015779 22052.110327136157 28585.586070147252 26041.03726877104 27441.66218306861 25114.77480299295 23567.17254215831 27440.464295244783 1.0478333708075496 0.9706097567788786 1.0638193478095224 0.8036347377313734 1.041731137001968 0.9490013357129583 1.0000436540654318 0.9152459861018147 0.8588474410851101 1.0 14.744017271802896 IDS(ph)LSLNGEFGYQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IDSLSLNGEFGYQK 14 0 Q8TEQ0-2;Q8TEQ0 Q8TEQ0-2 SNX29 Sorting nexin-29 1 IDS(0.694)LS(0.306)LNGEFGYQK 81.619 0.046096 0.0 6859.8 7929.5 8118.0 6614.5 10965.0 8369.0 9524.9 7289.5 7393.6 5923.9 True False 8021.028652774159 8716.688355760158 8311.563907686448 6243.911009498336 8816.486962911113 7930.114907217512 8622.632517695734 7098.158348863676 7501.7174126830205 6997.856176433398 1.1462122756661515 1.245622678716269 1.1877300273299713 0.892260551242234 1.2598839902715202 1.1332206188980665 1.2321820140765507 1.0143332714907838 1.0720022280461365 1.0 12.772697298528426 -7.780148553855014 24.98532132440379 1.032375747444444 1.1542328646259992 0.25770581491013267 0.09939402634108307 379.10323060817353 506269.3706471577 0.054727277470189475 0.02636145416404113 1.6590193297160625e-08 7.780148553855014 0.12185711718155523 IDS(ph)LSLNGEFGYQK ddPTM_PC-9_Lapatinib_30min_R1 1 IDSLSLNGEFGYQK 14 0 Q8TEQ0-2;Q8TEQ0 Q8TEQ0-2 SNX29 Sorting nexin-29 1 IDS(0.941)LS(0.059)LNGEFGYQK 117.2 0.00013348 5057800.0 22046.0 24969.0 28184.0 21203.0 23743.0 26360.0 25308.0 22476.0 24108.0 18956.0 True False 21731.619997258746 24911.18581459079 25866.820313386164 22762.339351134528 22346.48342053402 25232.64424816125 26618.324407004973 23520.31701267204 21392.703171505495 22232.519342717693 0.9774699692042316 1.120484162437061 1.1634677975377044 1.0238308578640853 1.005126008261122 1.1349430921073844 1.1972698188936406 1.0579240548541866 0.962225775753692 1.0 14.440383820370593 -8.114824422835083 4.976931326236625 0.9838936384520782 1.0913855224336504 0.2842477783275653 0.06711642064492868 0.30246073545609586 10.897195399306009 0.05029510314570441 0.01814776973533003 7.67671782028896e-09 8.114824422835083 0.10749188398157217 IDS(ph)PGFKPASQQK ddPTM_PC-9_AZD4547_30min_R2 2 IDSPGFKPASQQK 13 1 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 1 IDS(1)PGFKPASQQK;IDS(1)PGFKPASQQK 141.55 0.00037487 68670000.0 104349.0 111454.0 126260.0 159831.0 146261.0 132781.0 114610.0 130453.0 110573.0 135010.0 True False 137529.81140596615 147479.3258982394 124585.70990318155 122984.43231433412 125955.18479863218 124478.18307958433 124810.06797101053 110294.48636171833 116417.66304074644 130283.34099384562 1.0556208518820749 1.1319891305612595 0.9562673857823986 0.9439766540846056 0.9667788977301566 0.9554420552161346 0.9579894637251156 0.846573978839923 0.8935729015902796 1.0 16.99129309631619 -5.341218158688829 5.293462512224893 0.9355861125633075 1.093233010907821 0.666866183565148 0.043488745849846265 0.11908077294640981 5.752241374459047 0.01206690955624577 0.026107404873457023 4.558078929357753e-06 5.341218158688829 0.1576468983445135 IDS(ph)PGFKPASQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IDSPGFKPASQQK 13 1 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 1 IDS(1)PGFKPASQQK 116.58 0.0013117 7878900.0 30691.0 28137.0 30875.0 43301.0 46211.0 41679.0 38298.0 35363.0 36827.0 34990.0 True False 35886.38012511904 30930.255409045152 31611.17709408955 40874.98535373609 37156.28627843913 39493.27986831384 34670.13618649132 34434.75872019567 37365.52520516092 41333.410019312396 0.8682172631861654 0.7483112425176986 0.7647851236885541 0.9889091012485514 0.8989407421521339 0.9554808047499883 0.8387920611992148 0.8330974556443943 0.9040029648582698 1.0 15.33502077096601 -1.522878745280356 0.026995207559309575 1.5029197857667753 1.3473205214663077e-15 0.2867575844917273 0.06940971626952039 2494.6157043065073 5.192043055729696 96.51920097127748 213.9107250175626 0.029999999999998722 1.522878745280356 -1.502919785766774 IDS(ph)PGFKPASQQK ddPTM_PC-9_Lapatinib_30min_R1 2 IDSPGFKPASQQK 13 1 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 1 IDS(1)PGFKPASQQK;IDS(0.934)PGFKPAS(0.066)QQK 157.07 0.0010593 202781000.0 820434.0 737923.0 841556.0 798961.0 796692.0 639084.0 629316.0 760097.0 841065.0 616871.0 True False 808734.460710831 736214.3846313556 772366.5141801039 857719.2571957645 749832.1429167378 611751.8670975675 661898.9032131631 795413.8814905206 746335.4028929106 723496.3304210583 1.1178141846831013 1.0175786022340925 1.067547244822381 1.1855198445810933 1.0364007547631273 0.8455493709851187 0.914861451789193 1.0994027862278277 1.0315676410667631 1.0 19.464626173852047 -6.524271804234314 24.995541450945463 0.9761310043449951 1.092026637349637 0.3617529252070415 0.07429140655655998 57.51646848034175 1031979.6172888968 0.02649812505123716 0.026698389866430746 2.9903925065689553e-07 6.524271804234314 0.1158956330046419 IDS(ph)PGFKPASQQVYR ddPTM_PC-9_AZD4547_30min_R2 1 IDSPGFKPASQQVYR 15 1 A0A087X0K9;G5E9E7;Q07157-2 A0A087X0K9 TJP1 Tight junction protein ZO-1 1 IDS(1)PGFKPASQQVYR 88.10799999999999 0.023902 28950000.0 40299.0 41320.0 46687.0 64368.0 53637.0 37052.0 49934.0 47700.0 49863.0 52060.0 True False 53113.2437287278 54675.881943360066 46067.89987525613 49528.952075686546 46190.42839201322 34735.13258270953 54378.02926502431 40329.06103695551 52498.65638266795 50237.39524583073 1.0572451750100587 1.088350255338879 0.9170041489975411 0.9858980911196231 0.9194431392389244 0.6914198559208191 1.0824213516431709 0.8027697463136779 1.0450115123559254 1.0 15.61647404355324 -5.263944301687088 24.471171324201908 0.921923414008702 1.0727977257159276 0.21101710025734288 0.10906080120959892 211.3323427773422 2064590.4863579462 0.027052216132813146 0.060857261073082675 5.445724898430352e-06 5.263944301687088 0.15087431170722554 IDS(ph)PGFKPASQQVYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IDSPGFKPASQQVYR 15 1 A0A087X0K9;G5E9E7;Q07157-2 A0A087X0K9 TJP1 Tight junction protein ZO-1 1 IDS(1)PGFKPASQQVYR;IDS(1)PGFKPASQQVYR 147.75 2.0274e-09 9870200.0 37488.0 32790.0 38084.0 44925.0 55731.0 49168.0 53009.0 51743.0 39382.0 39075.0 True False 43833.97797824976 36045.174498439424 38992.06699437428 42407.99789881516 44810.91061833096 46589.543524682806 47987.60376807456 50384.80107624026 39957.88724657579 46158.98818247019 0.9496303906179772 0.7808917811618824 0.8447340058719552 0.9187375973488184 0.9707949065345591 1.0093276598809011 1.039615590757226 1.0915490798252574 0.865657780205646 1.0 15.494323979613187 -6.154255343257702 1.9495037328755365 1.0079876885487646 0.8511533191394881 0.4684096832907524 0.06610528439267116 0.2707778488425476 2.0283773249623116 0.021779218898576792 0.030847156173583964 7.010429992901579e-07 6.154255343257702 -0.15683436940927653 IDS(ph)PGFKPASQQVYR ddPTM_PC-9_Lapatinib_30min_R1 2 IDSPGFKPASQQVYR 15 1 A0A087X0K9;G5E9E7;Q07157-2 A0A087X0K9 TJP1 Tight junction protein ZO-1 1 IDS(1)PGFKPASQQVYR;IDS(1)PGFKPASQQVYR 178.47 3.4033000000000004e-05 27544300.0 56361.0 56168.0 56439.0 48487.0 60253.0 58782.0 61515.0 56001.0 61627.0 54376.0 True False 55557.281804658436 56037.94644695165 51798.80328084026 52052.8957278904 56709.0370019558 56268.03088753467 64699.94570479335 58603.01090170166 54685.9182989203 63774.81914853441 0.8711476182357027 0.8786845214948673 0.8122140363926165 0.8161982491342998 0.8892073354199236 0.8822922846160317 1.0145061415870782 0.9189051679662568 0.857484490415478 1.0 15.96069928221479 -6.830572184070098 2.3497923084058563 0.940525204912832 0.8472251142509962 0.4623533168044872 0.0471620263839883 0.28618575369434024 3.233161778024968 0.019007088439838456 0.01680881658230073 1.4771609423179532e-07 6.830572184070098 -0.09330009066183576 IDS(ph)TEVIYQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IDSTEVIYQPR 11 0 K7EMR0;K7EQN8;K7EP59;Q15831-2;Q15831 K7EMR0 STK11 Serine/threonine-protein kinase STK11 1 IDS(0.981)T(0.019)EVIYQPR;IDS(0.979)T(0.021)EVIYQPR 164.48 0.00019969 27921600.0 58233.0 68418.0 74491.0 71850.0 82636.0 65978.0 75071.0 59582.0 61169.0 52924.0 True False 68090.69674582302 75210.08688119023 76267.14794869049 67824.47744084301 66444.06900748942 62517.997532369045 67959.73141302653 58018.03563234734 62063.480904621276 62518.702253846546 1.089125242385108 1.203001408695473 1.219909326316799 1.0848670077227973 1.062787079899781 0.9999887278294 1.0870304239055957 0.9280108757980129 0.992718637258705 1.0 15.932000211128043 -6.256551048523157 1.5126189468754214 1.00022351177556 1.1726315661163675 0.6646392838167307 0.05078968346733812 0.2368979057125014 1.0822523951124112 0.01916103627095231 0.02636676858393846 5.539224300927397e-07 6.256551048523157 0.17240805434080753 IDSFSVQS(ph)LDSR ddPTM_PC-9_AZD4547_30min_R2 1 IDSFSVQSLDSR 12 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 IDSFSVQS(1)LDSR 130.47 0.0010363 0.0 13547.0 9575.3 11849.0 16096.0 13291.0 11697.0 9356.6 13651.0 11038.0 11245.0 True False 17854.664204895304 12670.328469802893 11691.87451800093 12385.315880721015 11445.774069359732 10965.584740903407 10189.319273864034 11541.551618773152 11621.446145476382 10851.315972711622 1.6453916050178035 1.1676305898441846 1.0774614385391694 1.1413653341094319 1.0547821202647703 1.0105304064943958 0.9389938786675878 1.0636084736447913 1.0709711314923875 1.0 13.405582392926945 -2.1411506362949035 1.054297919185927 1.0340598305804702 199.99994764177694 0.9281227117847922 0.05011877077774468 133.06625770176336 0.6158928239106298 0.016842856774435776 63440.980992234734 0.007225191522811559 2.1411506362949035 198.96588781119647 IDSFSVQS(ph)LDSR ddPTM_PC-9_Lapatinib_30min_R1 1 IDSFSVQSLDSR 12 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 IDSFSVQS(0.998)LDS(0.002)R 159.12 0.0005093 2428700.0 9627.1 7672.0 11230.0 7806.5 9022.6 6847.3 8001.1 6484.3 9985.9 7535.1 True False 9489.815788606078 7654.235955366275 10306.712749053599 8380.61605172059 8491.908407114104 6554.456940835902 8415.357808317029 6785.584250100962 8861.182785811214 8837.531995110365 1.0738083657130304 0.866105600477737 1.1662433306896205 0.9482982416762307 0.9608913904710628 0.741661466624659 0.9522294021648898 0.7678143913770603 1.0026761759633724 1.0 13.109427817679286 -6.3013060072378515 2.7244536300146533 0.8819486095823679 1.0185827152216484 0.2028702279158704 0.10974246765865464 0.39335456215569714 5.790596359706568 0.033930168687087134 0.04150790584192827 4.996823308886837e-07 6.3013060072378515 0.13663410563928058 IDSLS(ph)LNGEFGYQK ddPTM_PC-9_AZD4547_30min_R2 1 IDSLSLNGEFGYQK 14 0 Q8TEQ0-2;Q8TEQ0 Q8TEQ0-2 SNX29 Sorting nexin-29 1 IDS(0.023)LS(0.977)LNGEFGYQK 121.79 6.716199999999999e-05 7714500.0 24232.0 23126.0 34518.0 38024.0 34879.0 37042.0 30313.0 36098.0 38330.0 31690.0 True False 31937.271943088715 30601.02724642173 34060.26876633945 29258.154264943845 30036.652905364415 34725.75788429034 33010.79827593787 30519.883549518247 40356.04554775407 30580.542745685303 1.0443657657971044 1.0006698540606942 1.113788890197023 0.956757193888325 0.9822145131679317 1.1355507380322705 1.0794706474133937 0.9980164120476372 1.3196641368782775 1.0 14.900326391531362 -6.764414337945806 24.999776882990627 1.1047245568502546 1.020255809056838 0.1812873904708402 0.09237611231274329 143.3235168929896 1204395.728232571 0.0307441491763652 0.028307722430260498 1.7202266124462096e-07 6.764414337945806 -0.08446874779341651 IDSLS(ph)LNGEFGYQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IDSLSLNGEFGYQK 14 0 Q8TEQ0-2;Q8TEQ0 Q8TEQ0-2 SNX29 Sorting nexin-29 1 IDS(0.008)LS(0.992)LNGEFGYQK;IDS(0.171)LS(0.829)LNGEFGYQK 105.28 0.00098654 8625500.0 59891.0 62109.0 55055.0 61790.0 73089.0 63035.0 59925.0 52202.0 57556.0 51348.0 True False 70029.36339883033 68274.7710559186 56367.719997250184 58328.10662588289 58767.73512377661 59729.33363322447 54248.470180570606 50831.75281259092 58397.647614745765 60656.985929455645 1.1545143947685566 1.125587927090912 0.9292865303727109 0.9616057529419405 0.9688535330806539 0.9847065876746656 0.8943482658973828 0.8380197603571745 0.9627522159222105 1.0 15.888386191183443 -5.232977531681697 5.151551511035221 0.9377352740487438 1.1448912140178014 0.7533684836675413 0.045206370336223434 0.09061794779473693 6.884714511110617 0.012505484103723756 0.032979533091242415 5.84820339167709e-06 5.232977531681697 0.20715593996905757 IDSLS(ph)LNGEFGYQK ddPTM_PC-9_Lapatinib_30min_R1 1 IDSLSLNGEFGYQK 14 0 Q8TEQ0-2;Q8TEQ0 Q8TEQ0-2 SNX29 Sorting nexin-29 1 IDS(0.017)LS(0.983)LNGEFGYQK 134.88 3.0988e-05 3984100.0 45825.0 45532.0 35753.0 38834.0 42727.0 46579.0 39624.0 38587.0 45284.0 32923.0 True False 45171.52709672419 45426.57345147775 32813.52635057108 41689.98190642636 40213.88186451404 44586.92475095229 41675.53683827898 40379.89288876917 40183.6390583398 38613.69668286003 1.1698317171682522 1.1764367919645944 0.8497898199199472 1.079668239195856 1.0414408699274915 1.1546919508160864 1.079294147373827 1.0457401481245159 1.0406576554525184 1.0 15.236825056873391 -10.440889562786936 0.009643436248451494 2.813238027858398e-07 2.0470879118714094 0.08021693978690969 0.08785441594139312 18713.8567957937 35.450599120972925 3974.3319585955733 3556.957028087274 3.623351252931996e-11 10.440889562786936 2.0470876305476065 IDSLSAQLSQLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IDSLSAQLSQLQK 13 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ; 139.89 7.4064e-05 1911300.0 27099.0 24175.0 25861.0 29588.0 28892.0 27549.0 27199.0 26610.0 23932.0 21386.0 False True 31686.325470352935 26574.93423299096 26477.624318388658 27930.280285590266 23230.82000295737 26104.28194275722 24622.513816292692 25911.515695625567 24281.960225104176 25263.11250851716 1.254252636513821 1.051926369881444 1.048074512175095 1.1055755808463388 0.9195549437990024 1.033296349923489 0.9746429228778324 1.0256660055996587 0.9611626523421373 1.0 14.624744774968427 -1.5228787452979244 0.7537038702931276 0.996930882690272 45.190319622922615 0.7155375364414193 0.04685877454240681 202.06406194290295 0.8587764345747435 0.01682242940183258 15168.845044428163 0.02999999999878514 1.5228787452979244 44.19338874023234 IDSLSAQLSQLQK ddPTM_PC-9_Lapatinib_30min_R1 2 IDSLSAQLSQLQK 13 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ; 205.12 4.074e-09 13734800.0 42581.0 35639.0 42246.0 40221.0 40677.0 39217.0 44950.0 31598.0 34830.0 35127.0 False True 41973.78713160094 35556.480085153635 38772.69695427592 43178.98651332275 38284.45883405898 37539.78032929207 47277.291057960865 33066.15843417025 30907.0786238401 41198.655146214645 1.0188144972848103 0.8630495330239095 0.9411155975036329 1.0480678643533359 0.9292647708568851 0.9111894598516099 1.1475445227562173 0.8026028596520434 0.750196299227497 1.0 15.330309623619257 IDSNIS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IDSNISPK 8 0 Q9H501 Q9H501 ESF1 ESF1 homolog 1 IDS(0.013)NIS(0.987)PK 72.531 0.032425999999999996 62954000.0 161200.0 190760.0 120540.0 162420.0 175900.0 94315.0 169190.0 170210.0 137500.0 115370.0 True False 188487.9761548726 209697.3921110796 123414.13075049571 153320.13397274463 141433.6577087154 89368.95536793167 153163.09837047523 165742.16785240226 139510.67737555646 136285.66773158262 1.3830359368829852 1.5386606354241361 0.905554727835082 1.1249908851362986 1.037773524265749 0.6557472759640848 1.1238386318958575 1.2161379153883944 1.02366360085879 1.0 17.056274325796593 -5.258964714831923 24.99357433431891 1.0150574217119377 1.4608483188884016 0.5971521175180443 0.14777452043865608 146.89606494786386 1483596.1128353681 0.03990521418557231 0.09580640921794582 5.508524497525205e-06 5.258964714831923 0.4457908971764639 IDSVAAQPT(ph)ATSPVVYTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IDSVAAQPTATSPVVYTR 18 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 IDS(0.004)VAAQPT(0.663)AT(0.287)S(0.041)PVVY(0.001)T(0.005)R 64.798 0.038100999999999996 2787500.0 1677.7 3655.4 4074.9 3249.2 5321.5 2970.7 3234.3 3044.7 3732.9 3434.7 True False 1961.7014739145754 4018.283954303001 4172.061070144307 3067.157858048531 4278.790275707382 2814.9112623815345 2927.9236896957777 2964.7798511263086 3787.486600547023 4057.383920929759 0.4834892413792203 0.990363256869762 1.0282638151699162 0.755944696834527 1.0545687465353013 0.6937749341049518 0.7216284548751396 0.7307121802875688 0.9334799650113248 1.0 11.986334105474885 IDSVAAQPTAT(ph)SPVVYTR ddPTM_PC-9_Lapatinib_30min_R1 1 IDSVAAQPTATSPVVYTR 18 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 IDSVAAQPT(0.001)AT(0.967)S(0.033)PVVYTR 281.53 4.4060999999999996e-92 17568000.0 19228.0 49178.0 44847.0 39726.0 86099.0 81114.0 98449.0 86631.0 69417.0 75629.0 True False 18953.80519401665 49064.131362487315 41159.85277442626 42647.58256205114 81034.82609714687 77644.94330596935 103546.20750534342 90656.19252201429 61598.52646658369 88701.37188069208 0.21368108285304196 0.5531383598946035 0.46402723995958467 0.48079958243954035 0.9135690280657991 0.875352225785254 1.1673574524260844 1.0220382233090097 0.6944484077364315 1.0 16.436668797380925 -6.2601877783200965 2.7783803699130103 0.9648133924342475 0.4242087726339831 0.772587817108666 0.13784579871323283 0.13267278583465303 2.0504212831114916 0.045202981660595026 0.05683402467244954 5.493033171747477e-07 6.2601877783200965 -0.5406046198002643 down IDSVAAQPTATS(ph)PVVYTR ddPTM_PC-9_AZD4547_30min_R2 2 IDSVAAQPTATSPVVYTR 18 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 IDSVAAQPTAT(0.025)S(0.975)PVVYTR;IDSVAAQPT(0.011)AT(0.443)S(0.546)PVVYTR 285.34 1.0115e-105 44040000.0 115030.0 139414.0 129671.0 131127.0 129255.0 164130.0 127001.0 182928.0 141414.0 125009.0 True False 151607.14722736453 184476.84911063904 127951.4778144737 100897.69604195494 111310.17435370489 153866.92515384065 138303.84296646254 154660.68086725756 148888.85533759702 120632.47295977808 1.2567689570445446 1.5292470143768693 1.060671929167331 0.8364057667589786 0.9227214830522336 1.2755017067845718 1.146489328893859 1.2820816573894274 1.2342352907516065 1.0 16.880258791889595 -5.273732870475216 24.683074859446226 1.0977686115818235 1.393007987811567 0.3785051990589239 0.15282875691265949 639.5789629145887 1284158.1519107174 0.044134332383423874 0.09297114887411706 5.324356535953412e-06 5.273732870475216 0.2952393762297436 IDSVAAQPTATS(ph)PVVYTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IDSVAAQPTATSPVVYTR 18 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 IDSVAAQPT(0.232)AT(0.32)S(0.448)PVVYTR;IDSVAAQPT(0.001)AT(0.394)S(0.605)PVVYTR 214.24 2.1521999999999997e-27 19393300.0 56335.0 80749.0 60068.0 52744.0 65664.0 44840.0 75730.0 51487.0 50847.0 52033.0 True False 65871.40283303178 88765.22706845037 61500.24892915857 49788.92467835515 52797.61057296812 42488.511463691386 68556.30616227965 50135.5208049858 51590.54118192675 61466.1710069986 1.0716692085070925 1.4441313915315057 1.0005544175210799 0.8100215754888349 0.8589702222862806 0.6912503376670982 1.115350200592026 0.8156603865771518 0.8393322755707785 1.0 15.907504995719973 -5.471495373298269 5.560860896025473 0.8715602225829991 1.255337224150362 0.5502847338144727 0.13650339691866128 0.13701503518973449 9.614597848618963 0.034487735070509326 0.07152688283232547 3.376794460484484e-06 5.471495373298269 0.38377700156736283 IDSVAAQPTATS(ph)PVVYTR ddPTM_PC-9_Lapatinib_30min_R1 1 IDSVAAQPTATSPVVYTR 18 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 IDSVAAQPT(0.003)AT(0.082)S(0.915)PVVYTR 199.91 6.9715000000000006e-15 18629000.0 23704.0 49008.0 48737.0 40389.0 81295.0 80463.0 95638.0 87353.0 75025.0 70243.0 True False 23365.976613218776 48894.52498704255 44730.031990260475 43359.34179375432 76513.38793211948 77021.78505841417 100589.66767967213 91411.73927780485 66574.89445172556 82384.40895708567 0.2836213418171173 0.5934924533173731 0.542942925202759 0.5263051873849135 0.9287362609104299 0.9349072965800493 1.2209794177448021 1.1095757126256929 0.808100650286933 1.0 16.33008371636882 -6.317535516001114 1.941421110870531 1.0388917222442973 0.47580935503457017 0.8004035788206657 0.12619867003369703 0.14789573486151492 1.0967875992482634 0.04489119520609516 0.05631868998729571 4.813538879363661e-07 6.317535516001114 -0.5630823672097272 down IDTHPS(ph)PSHSSTVK ddPTM_PC-9_AZD4547_30min_R2 2 IDTHPSPSHSSTVK 14 0 A0A0C4DG98;Q8NI27;Q8NI27-2;H0Y7U4;H7C477;H0Y594;B7ZBA0 A0A0C4DG98 THOC2 THO complex subunit 2 1 IDT(0.001)HPS(0.997)PS(0.001)HSSTVK;IDT(0.008)HPS(0.933)PS(0.04)HS(0.001)S(0.007)T(0.011)VK 124.78 2.1003000000000002e-05 59781000.0 49991.0 55185.0 170768.0 420840.0 256610.0 223722.0 105475.0 336390.0 132453.0 243240.0 True False 65887.0981226043 73022.47204850748 168503.50474217086 323821.83991318516 220984.13091102245 209732.62797335992 114862.07066785054 284408.65497319633 139454.1951718412 234724.24163649362 0.28070001489083746 0.31109897954892085 0.7178785777189741 1.3795841352197136 0.9414627537842903 0.8935277690583104 0.4893489904026701 1.2116714191525502 0.594119270338542 1.0 17.84060732133718 -5.3615598584947675 3.7920787955683903 0.9261617504341825 0.2911715665643723 0.506838652991425 0.2458111247235526 0.18041714936111614 4.657882232285001 0.06554446255260109 0.15159660907182093 4.349508075434901e-06 5.3615598584947675 -0.6349901838698102 IDTHPS(ph)PSHSSTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IDTHPSPSHSSTVK 14 0 A0A0C4DG98;Q8NI27;Q8NI27-2;H0Y7U4;H7C477;H0Y594;B7ZBA0 A0A0C4DG98 THOC2 THO complex subunit 2 1 IDT(0.007)HPS(0.951)PS(0.038)HS(0.003)STVK 77.13 0.0087788 25052000.0 12048.0 13214.0 50529.0 43346.0 57898.0 51955.0 32725.0 30176.0 40463.0 23816.0 True False 14087.48844115325 14525.798591716339 51733.80299229962 40917.46414962808 46553.30252427061 49230.38833844974 29625.051091517293 29383.911974114857 41054.69482652471 28133.652272647734 0.500734433788729 0.5163140018560156 1.8388584066846012 1.4543957447504638 1.65471948231659 1.7498754822640925 1.0530112053854996 1.0444400069123858 1.4592735571143443 1.0 14.780009233076834 -5.243421241915305 24.612214943882915 1.4185772582890264 0.5085238950350188 0.6189884949579842 0.28178762409583075 446.4279459754074 609803.7976764869 0.07531588036288424 0.19836192242918585 5.709246023578426e-06 5.243421241915305 -0.9100533632540075 IDTHPS(ph)PSHSSTVK ddPTM_PC-9_Lapatinib_30min_R1 1 IDTHPSPSHSSTVK 14 0 A0A0C4DG98;Q8NI27;Q8NI27-2;H0Y7U4;H7C477;H0Y594;B7ZBA0 A0A0C4DG98 THOC2 THO complex subunit 2 1 IDT(0.056)HPS(0.934)PS(0.01)HSSTVK 105.0 0.0005741 37586000.0 17534.0 26400.0 107310.0 35562.0 56461.0 77460.0 44298.0 43099.0 108000.0 31196.0 True False 17283.9619446582 26338.872422011158 98487.38602857878 38177.34811135436 53140.07498659696 74147.21636807933 46591.53368822135 45101.536880634965 95835.90270958164 36588.18703394287 0.4723918659490798 0.7198736684486875 2.691780982129888 1.0434337201768764 1.4523833864000668 2.026534310084644 1.2734037257707898 1.2326802866398998 2.6193126929376045 1.0 15.159090310614806 -5.029004908604574 24.109230728798245 1.6486227427654354 0.5342616725920116 0.3593628568616446 0.5758763457043568 385.14200068519887 320136.47863887384 0.13871470195781085 0.36875211405545133 9.353951018036367e-06 5.029004908604574 -1.1143610701734237 IDTIEIITDR ddPTM_PC-9_AZD4547_30min_R2 4 IDTIEIITDR 10 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;;; 162.64 0.00054486 28339800.0 53235.0 63232.0 61553.0 71947.0 65558.0 72934.0 64864.0 83470.0 72451.0 68422.0 False True 70162.62264321258 83670.50743084561 60736.76700198426 55360.730720069296 56456.40331345158 68373.42545037607 70636.77034178177 70571.62944978366 76280.61194835193 66026.56660603605 1.0626423006644483 1.26722487222585 0.9198837698828913 0.8384614491677703 0.8550558694095479 1.0355441599491784 1.069823466109538 1.068836880022353 1.1553018106105561 1.0 16.010759007035283 -9.383647753751196 12.630627645702749 1.0 1.0256810059086534 0.004053609911840672 0.12481047733670274 0.0 0.0 0.1335800956297866 0.03239793198598343 4.133826512005833e-10 9.383647753751196 0.02568100590865341 IDTIEIITDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IDTIEIITDR 10 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;; 140.11 0.00056398 18049500.0 47149.0 52915.0 48616.0 51144.0 57688.0 44617.0 52080.0 40227.0 34465.6 32165.1 False True 55130.394464802004 58168.05149694794 49775.1898172067 48278.567491085174 46384.450516772995 42277.20597626044 47146.605373452105 39171.083874029646 34969.5941974908 37996.378011208515 1.4509381512242863 1.5308841142644967 1.3099982793760911 1.2706097269809118 1.2207597919751743 1.1126641061363567 1.2408184106270437 1.0309162589780163 0.9203402015627687 1.0 15.213574280360529 -5.766164050753151 0.35409426067163785 0.9548012993816747 1.6990864341022338 0.8562963556501029 0.07044106550308075 1.1742166871744908 0.19691182620358225 0.0753990183485833 0.3528838230482736 1.7133099981371537e-06 5.766164050753151 0.7442851347205591 IDTIEIITDR ddPTM_PC-9_Lapatinib_30min_R1 4 IDTIEIITDR 10 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;;; 153.97 0.00074871 126907000.0 102502.0 107014.0 103291.0 107225.0 98033.0 101305.0 118619.0 113169.0 115511.0 112542.0 False True 101040.30268343558 106766.21565792071 94798.81269479015 115110.68419211423 92266.89168029359 96972.42130348927 124760.5114127755 118427.24488374605 102500.93479524525 131994.7347472109 0.7654873724845347 0.8088672314270227 0.7182014712658323 0.8720854238054868 0.6990194863226786 0.7346688600057082 0.9451930916161921 0.8972118858418969 0.7765532086681294 1.0 17.010120856250914 -7.257125923046999 24.951234149318307 0.8961738717191015 0.7678710502049061 0.48553946618518373 0.06953411419182594 338.0565477131483 1955498.9258167155 0.026593901415593993 0.019864107665058476 5.531896894223704e-08 7.257125923046999 -0.12830282151419536 IDVDAPDIDIHGPDAK ddPTM_PC-9_AZD4547_30min_R2 1 IDVDAPDIDIHGPDAK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 161.04 4.8407e-05 4744300.0 28079.0 27035.0 33150.0 39844.0 37111.0 43660.0 33552.0 44018.0 35839.0 38017.0 False True 37007.53792051785 35773.53505176042 32710.409340174796 30658.581383663528 31958.778232488843 40929.9332980972 36538.063001163435 37216.029533012756 37733.37637323137 36686.036401474215 1.0087635937424604 0.9751267392386622 0.8916310549934563 0.835701656296441 0.8711428479966451 1.1156815320733982 0.9959664925725028 1.0144467264257864 1.0285487360993586 1.0 15.16294342224357 -6.747779205528738 24.999989112731583 1.029646492901959 0.9138642798399101 0.5147342288998669 0.05552959373959201 211.68112606653048 387404.8353755566 0.02006612873065585 0.01996228018600768 1.7873960525805933e-07 6.747779205528738 -0.11578221306204894 IDVDAPDIDIHGPDAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IDVDAPDIDIHGPDAK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ; 121.13 6.7439e-05 10742400.0 78902.0 87244.0 93157.0 82647.0 106557.0 91765.0 90332.0 76304.0 74711.0 66918.0 False True 92258.55021446514 95905.00774449084 95378.21617988993 78016.55653518932 85677.9207758246 86952.68185695002 81775.09901295445 74301.10085077083 75803.50703567441 79049.70367740354 1.167095459218494 1.2132241271374355 1.2065600722441914 0.9869304109420773 1.0838487279531164 1.0999747982838493 1.0344769835782441 0.9399288978234324 0.958934739907734 1.0 16.270472434113593 -5.985655007989728 0.47808954278890514 0.9649831147332972 1.252370033060191 0.6690468408794643 0.05517579318433674 1.0641567388859463 0.4093283182373915 0.04843419645694698 0.15412877292007152 1.0335821299503003e-06 5.985655007989728 0.2873869183268938 IDVDAPDIDIHGPDAK ddPTM_PC-9_Lapatinib_30min_R1 3 IDVDAPDIDIHGPDAK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ;; 96.163 0.0019833 10428100.0 85195.0 75512.0 80596.0 80379.0 81721.0 73627.0 63576.0 63006.0 74511.0 58892.0 False True 83980.10367715039 75337.15660344329 73969.70798955695 86290.33979648384 76914.33144966775 70478.14484291992 66867.65420024286 65933.48877471144 66118.7865443855 69071.40373134265 1.2158447510896986 1.090714138320855 1.070916529759067 1.2492918217228546 1.1135481153507554 1.0203664763647902 0.9680946178584786 0.9545699842899339 0.9572526830576437 1.0 16.075800923246316 -6.825958871478204 2.6873425154430057 0.9681293870854714 1.1492572186202503 0.7406986768488395 0.05071089453896414 0.14550232580002553 2.1417950507586316 0.01987376938459279 0.017738588486217153 1.492935786771756e-07 6.825958871478204 0.18112783153477896 IDVPPTANT(ph)PTPVRK ddPTM_PC-9_AZD4547_30min_R2 1 IDVPPTANTPTPVRK 15 1 E7EUN2;A0A087X1U1;F5GXM9;Q9UPQ3-2;Q9UPQ3;A0A087X044;Q9UPQ3-3 E7EUN2 AGAP1 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 1 IDVPPT(0.01)ANT(0.937)PT(0.053)PVRK 73.953 0.014051 7228200.0 18521.0 20614.0 35543.0 52130.0 39449.0 47317.0 47187.0 41889.0 41210.0 43058.0 True False 24410.292739268156 27277.072371259077 35071.676596616344 40112.23390047132 33972.187289306465 44358.260509987755 51386.551586668465 35416.017563459725 43388.27646811757 41550.5525258352 0.5874841910727995 0.6564791732745023 0.8440724482498654 0.9653838869057262 0.817610963613139 1.0675733007980288 1.2367236646183577 0.8523597259371904 1.044228628274912 1.0 15.342580041165585 -5.169739506851458 0.7555076378158544 1.0286254541824515 0.42896008313807044 0.6765801393484474 0.10565851302328266 1.0716571248702758 0.6716409351455114 0.04705972226110219 0.49602806323022675 6.76488616767578e-06 5.169739506851458 -0.5996653710443811 IDVPPTANT(ph)PTPVRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IDVPPTANTPTPVRK 15 1 E7EUN2;A0A087X1U1;F5GXM9;Q9UPQ3-2;Q9UPQ3;A0A087X044;Q9UPQ3-3 E7EUN2 AGAP1 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 1 IDVPPT(0.013)ANT(0.946)PT(0.041)PVRK 74.732 0.013325 7938300.0 18140.0 23578.0 37089.0 40717.0 44436.0 52904.0 40269.0 39374.0 37951.0 30530.0 True False 21210.743718668647 25918.668018426484 37973.342420815796 38435.758496295086 35729.08478649503 50129.62110783072 36454.42879768704 38340.47422020143 38505.96157876185 36064.84732465298 0.5881279221212602 0.7186684525546061 1.0529184299321355 1.0657402248316579 0.9906900330081686 1.3899856737661391 1.0108022493351234 1.063098198505138 1.0676868040542122 1.0 15.13830569593294 -5.178212333340904 2.325034091785541 1.0936857268000069 0.5848028936914187 0.7188779356664581 0.10820559420272026 0.17177295047809565 1.688832894016582 0.029717145125414537 0.12327268851505471 6.634186353871453e-06 5.178212333340904 -0.5088828331085882 IDVPPTANTPT(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 1 IDVPPTANTPTPVR 14 0 E7EUN2;A0A087X1U1;F5GXM9;Q9UPQ3-2;Q9UPQ3;A0A087X044;Q9UPQ3-3 E7EUN2 AGAP1 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 1 IDVPPT(0.002)ANT(0.125)PT(0.873)PVR 115.04 0.001342 0.0 14056.0 12358.0 19687.0 31898.0 26263.0 25205.0 18903.0 29236.0 22225.0 27883.0 True False 18525.51561703759 16352.481826138515 19425.937516742706 24544.40891918733 22616.835782378665 23628.927365518546 20585.330380036732 24718.24797644511 23399.76812676323 26906.82465692469 0.6885062006850331 0.6077447649301149 0.7219706436724885 0.9122001288572945 0.840561310030243 0.8781759894301555 0.7650598181877596 0.9186609082125068 0.8696592193661583 1.0 14.715684524447957 -3.3196033755807735 0.26227283223649017 0.9460020851658816 2.946617443732934e-24 0.6602955101633619 0.06693259882928863 13.081706619448106 0.40805915925610586 0.08899488332691091 4.572763196444426 0.0004790674064074998 3.3196033755807735 -0.9460020851658816 IDVPQDLEDDLTATPLSHATVPQS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 2 IDVPQDLEDDLTATPLSHATVPQSPAR 27 0 E7EUC4;Q9NRH2 E7EUC4 SNRK SNF-related serine/threonine-protein kinase 1 IDVPQDLEDDLTAT(0.003)PLS(0.133)HAT(0.259)VPQS(0.605)PAR;IDVPQDLEDDLTATPLS(0.058)HAT(0.326)VPQS(0.616)PAR 138.85 8.7635e-13 8806000.0 16983.1 15005.900000000001 31817.0 48279.0 39067.0 36664.0 24107.2 45168.0 31497.0 41355.0 True False 22383.37252957536 19856.26371863182 31395.0857911415 37149.02245311443 33643.2213955065 34371.3942840457 26252.69409816545 38188.32345738377 33161.867117600064 39907.174037482335 0.5608859326534134 0.4975612580330059 0.7867028059078812 0.9308858206352234 0.843036927744057 0.8612835940666403 0.6578439774639999 0.9569287823165791 0.8309750794795236 1.0 15.284360499880474 -5.351252350973135 4.108565813602854 0.8566733164000624 0.5283030569587044 0.6896876882605711 0.0892697905287304 0.11831867798269763 3.5748602317189593 0.02321841245890431 0.05279080985361645 4.4539737077994454e-06 5.351252350973135 -0.328370259441358 IDVPQDLEDDLTATPLSHATVPQS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 1 IDVPQDLEDDLTATPLSHATVPQSPAR 27 0 E7EUC4;Q9NRH2 E7EUC4 SNRK SNF-related serine/threonine-protein kinase 1 IDVPQDLEDDLTATPLS(0.071)HAT(0.382)VPQS(0.546)PAR 130.2 1.1997e-10 1985800.0 2809.5 2042.1 5144.2 3660.5 5152.0 4058.2 3384.8 2798.1 5659.9 3081.3 True False 2769.436014800802 2037.3716429162494 4721.263733186248 3929.705381070033 4848.96948922172 3884.6402461262496 3560.0483820464046 2928.1099409662565 5022.422460610752 3613.8985994258323 0.7663291978476661 0.5637600466266381 1.3064184296527719 1.0873867301352549 1.3417558229199107 1.074916780106512 0.9850991343841293 0.8102357773490013 1.3897519043308804 1.0 11.81934031157356 -5.25460297282288 24.97171221302404 1.1173602867007235 0.665044588503573 0.5217941382444837 0.17581311533209384 411.7778843644025 1504113.4900963542 0.04495546277358178 0.11339763580506267 5.564126911162452e-06 5.25460297282288 -0.45231569819715056 IDYLLPGPGPAHS(ph)PQPSKR ddPTM_PC-9_AZD4547_30min_R2 2 IDYLLPGPGPAHSPQPSKR 19 1 Q8TDM6-4;Q8TDM6;A0A0J9YYG8;Q8TDM6-3 Q8TDM6-4 DLG5 Disks large homolog 5 1 IDYLLPGPGPAHS(0.963)PQPS(0.037)KR;IDYLLPGPGPAHS(0.936)PQPS(0.064)KR 94.176 0.00028494 16492500.0 75805.0 80612.0 110162.0 144967.0 131624.0 139484.0 120301.0 136418.0 110353.0 139309.0 True False 99909.4131580489 106668.25254642169 108701.1799014279 111547.09786782335 113350.27959562164 130762.04342995398 131007.55594608239 115337.73267378217 116186.03428988534 134431.83431235977 0.7431975742137378 0.7934746490074079 0.8085970146688225 0.8297669851669027 0.8431803387599847 0.9727014743109222 0.9745277717603638 0.8579644342707442 0.864274707580949 1.0 17.036515292361635 -6.312894235838562 1.6427913439726454 0.9261058556470486 0.7835756146332938 0.6505084733442921 0.048237891595719694 0.26473039211530697 1.4186344332980951 0.01879757694043817 0.024282904785986145 4.865256753406018e-07 6.312894235838562 -0.14253024101375478 IDYLLPGPGPAHS(ph)PQPSKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IDYLLPGPGPAHSPQPSKR 19 1 Q8TDM6-4;Q8TDM6;A0A0J9YYG8;Q8TDM6-3 Q8TDM6-4 DLG5 Disks large homolog 5 1 IDYLLPGPGPAHS(0.987)PQPS(0.013)KR;IDYLLPGPGPAHS(0.5)PQPS(0.5)KR 70.072 0.0026719 16134100.0 46205.0 60520.0 75566.0 88088.0 97111.0 90014.0 83341.0 81177.0 81782.0 69209.0 True False 54026.593909651885 66528.02563725384 77367.78002565078 83152.71494514903 78082.7966671463 85293.50737940928 75446.33714341164 79046.18976414109 82977.90703365653 81756.04384185743 0.6608269110251561 0.8137383184286718 0.9463249001542323 1.0170833988248404 0.9550706345109312 1.0432685263537755 0.922822749218996 0.9668543883684235 1.0149452338247014 1.0 16.31903776579778 -4.962486973874949 1.68579920737948 0.9862540971570437 0.608808171441323 0.9084876546951768 0.0332261744162479 0.1767631183611651 0.6545511084227734 0.009280346581098654 0.09748446339777643 1.0902171916090169e-05 4.962486973874949 -0.37744592571572066 IDYLLPGPGPAHS(ph)PQPSKR ddPTM_PC-9_Lapatinib_30min_R1 2 IDYLLPGPGPAHSPQPSKR 19 1 Q8TDM6-4;Q8TDM6;A0A0J9YYG8;Q8TDM6-3 Q8TDM6-4 DLG5 Disks large homolog 5 1 IDYLLPGPGPAHS(0.986)PQPS(0.014)KR;IDYLLPGPGPAHS(0.787)PQPS(0.213)KR 73.346 0.0018178 16219800.0 186429.0 184518.0 211127.0 205338.0 209440.0 200175.0 146671.0 165030.0 215059.0 137818.0 True False 183770.48827310812 184090.75990775245 193768.95303378784 220439.24150748728 197121.15097488282 191613.98188071622 154264.90671328543 172697.8962716344 190836.79074833277 161639.65766905807 1.1369146094664517 1.1388960021473251 1.1987711173610096 1.3637695395199105 1.2195098270900186 1.185439171574019 0.9543753614544783 1.0684129053602491 1.1806310004630984 1.0 17.302421675641007 -7.093952651786084 6.951732266896948 1.0569804780654064 1.2140829723747042 0.4817397535395487 0.07969099439721858 0.2510609918733375 15.99119383840458 0.03265862905256579 0.02530654488220174 8.054662509942341e-08 7.093952651786084 0.1571024943092978 IEADSESQEDIIR ddPTM_PC-9_AZD4547_30min_R2 2 IEADSESQEDIIR 13 0 P55957;P55957-2 P55957 BID BH3-interacting domain death agonist;BH3-interacting domain death agonist p15;BH3-interacting domain death agonist p13;BH3-interacting domain death agonist p11 0 ; 110.98 0.0021781999999999995 0.0 6278.0 8817.9 10740.5 15039.6 11237.900000000001 12226.2 9289.3 12271.4 10541.3 12276.9 False True 8274.273409487909 11668.113731567155 10598.073952281975 11572.452579503724 9677.71156527408 11461.693781245896 10116.02970424141 10375.137098718988 11098.491597509528 11847.089467797527 0.6984224633382604 0.9848928518082978 0.894571952131315 0.9768181974956538 0.816885159142235 0.9674691672077599 0.8538831188654866 0.8757540936042085 0.936811663968368 1.0 13.53224504828241 -13.397041039973935 0.013569818300842399 2.0053921330715383 7.992076133427674e-07 0.1825102648798007 0.08051398765014871 12543.651938711224 15.52330576810668 1358.0262929296994 965.9510300282135 4.008288383011018e-14 13.397041039973935 -2.005391333863925 IEADSESQEDIIR ddPTM_PC-9_Lapatinib_30min_R1 2 IEADSESQEDIIR 13 0 P55957;P55957-2 P55957 BID BH3-interacting domain death agonist;BH3-interacting domain death agonist p15;BH3-interacting domain death agonist p13;BH3-interacting domain death agonist p11 0 ; 164.48 0.00045854 3747300.0 13704.400000000001 13392.2 13554.1 11760.8 15146.5 12562.7 10815.8 11063.6 13912.1 9123.2 False True 13508.97274292084 13361.191183714314 12439.734218339034 12625.7284648787 14255.612649164745 12025.422606084043 11375.789201884156 11577.655245657512 12345.17279709232 10700.132964100134 1.262505128510515 1.248693939462459 1.1625775361928128 1.1799599600527493 1.3322836918936942 1.123857305926045 1.063144658113213 1.0820104090763676 1.1537401300069294 1.0 13.385341103788583 -6.955430065148958 9.369736285440734 1.0832245200388426 1.2304918414981272 0.6567344214934558 0.0558477488243931 0.229761871947925 45.805468225340576 0.019740424867129187 0.017385407762907184 1.1080769856929889e-07 6.955430065148958 0.14726732145928456 IECDDKGDGSCDVR ddPTM_PC-9_AZD4547_30min_R2 1 IECDDKGDGSCDVR 14 1 Q60FE5;P21333-2;P21333;A0A087WWY3;Q14315-2;Q14315 Q60FE5;Q14315-2 FLNA;FLNC Filamin-A;Filamin-C 0 82.705 0.011575 13207000.0 36079.0 30536.0 39559.0 52387.0 51921.0 48082.0 43289.0 44462.0 41604.0 44235.0 False True 47551.37151018067 40406.16483597396 39034.421812608576 40309.98652108176 44712.66537169715 45075.4249390543 47141.63713809505 37591.41953511771 43803.10250375061 42686.34611408609 1.1139714648588572 0.9465828892447722 0.9144474841740458 0.9443297492211413 1.0474699626947548 1.0559682203434093 1.1043727427993364 0.8806427103094894 1.0261619110401208 1.0 15.38148705493202 -4.748264909312622 24.812288082620697 0.9908486859805162 1.1139717916193175 0.23685655512530857 0.06615964310285731 967.4420413047334 1821924.061952618 0.017498645116643077 0.32222172647560643 1.7853981921711766e-05 4.748264909312622 0.12312310563880124 IECDDKGDGSCDVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IECDDKGDGSCDVR 14 1 Q60FE5;P21333-2;P21333;A0A087WWY3;Q14315-2;Q14315 Q60FE5;Q14315-2 FLNA;FLNC Filamin-A;Filamin-C 0 87.667 0.007802199999999999 9316200.0 44448.0 46939.0 35124.0 49118.0 47628.0 46352.0 51200.0 47519.0 41617.0 33739.0 False True 51972.16851198368 51598.79371095604 35961.48936851179 46366.07770270456 38295.635300458765 43921.219521967505 46349.96534410038 46271.67660054231 42225.56989337122 39855.61362222293 1.3040112493213434 1.2946430633346282 0.9022942090260573 1.1633512443740543 0.9608592572040003 1.102008362944327 1.1629469761382947 1.1609826670625358 1.0594635499433593 1.0 15.282495320190936 -5.1711929282673275 10.450020975992034 1.074542803638185 1.3005635846915398 0.5480854455317269 0.08505270967688353 0.41004001647304905 45.53787202179188 0.021239840168576486 0.05635303392712577 6.742284461281512e-06 5.1711929282673275 0.22602078105335477 IECDDKGDGSCDVR ddPTM_PC-9_Lapatinib_30min_R1 3 IECDDKGDGSCDVR 14 1 Q60FE5;P21333-2;P21333;A0A087WWY3;Q14315-2;Q14315 Q60FE5;Q14315-2 FLNA;FLNC Filamin-A;Filamin-C 0 ;; 87.641 0.0078158 75609000.0 123197.0 161103.0 159298.0 166717.0 173530.0 154797.0 162442.0 149840.0 161953.0 142393.0 False True 121440.1881884371 160729.9759016385 146201.13334806263 178977.9243316088 163323.3065731067 148176.69315943163 170852.45192518982 156802.11341781355 143712.1476993046 167005.44032325404 0.7271630669837983 0.9624235928514137 0.8754273697017128 1.0716891856048578 0.9779520131618453 0.8872566838099545 1.0230352472020645 0.938904224403163 0.860523749532571 1.0 17.34953557473817 -4.760334635640685 24.968994692514308 0.9551844168679111 0.7271627926180001 0.5333923999859846 0.06399793390315392 21.40611704205544 483590.6010619508 0.015692062717470787 0.09370740156642725 1.7364623219685235e-05 4.760334635640685 -0.22802162424991101 IEDDMDGGDWSFCDGR ddPTM_PC-9_AZD4547_30min_R2 2 IEDDMDGGDWSFCDGR 16 0 P23229-4;P23229-2;P23229-5;P23229-3;P23229-9;P23229-6;P23229;C9JXX7;P23229-7 P23229-4 ITGA6 Integrin alpha-6;Integrin alpha-6 heavy chain;Integrin alpha-6 light chain;Processed integrin alpha-6 0 ; 108.32 0.0055243 0.0 12909.6 15191.4 15861.3 22924.3 22177.0 15626.400000000001 18264.7 20336.9 15345.9 16870.0 False True 17014.5842636389 20101.72296598162 15650.968798410677 17639.456811904376 19098.106352884715 14649.278737732162 19890.222916587678 17194.299400470878 16157.052944724215 16279.386434828368 1.0451612738449183 1.234796105274317 0.9613979532377679 1.0835455551424378 1.1731465697027705 0.8998667607270058 1.2218042121068047 1.056200703220923 0.9924853746427181 1.0 13.990758705436694 -14.52287874527259 0.06711634331740021 0.6934683616147588 1.1901127462796208 0.0684914305326263 0.10276923529018003 974.8334558527982 4.713586787304582 45.79349079421532 6.17136258463326 3.0000000000535134e-15 14.52287874527259 0.49664438466486205 IEDDMDGGDWSFCDGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IEDDMDGGDWSFCDGR 16 0 P23229-4;P23229-2;P23229-5;P23229-3;P23229-9;P23229-6;P23229;C9JXX7;P23229-7 P23229-4 ITGA6 Integrin alpha-6;Integrin alpha-6 heavy chain;Integrin alpha-6 light chain;Processed integrin alpha-6 0 83.226 0.044851 0.0 4616.4 5338.3 5335.5 5872.5 6901.2 5049.5 3875.6 5662.0 5542.9 3698.7 False True 5397.865341943882 5868.251144404365 5462.718554996427 5543.482863901879 5548.959400678715 4784.695330863285 3508.4751110858465 5513.378499384889 5623.954426363442 4369.245031106908 1.2354228942331447 1.343081265212928 1.25026601074202 1.2687507394149256 1.27000416803654 1.0950851455568575 0.8029934430564556 1.261860678477015 1.2871684664795888 1.0 12.09316830032066 -6.762258914668851 6.7881505269799565 1.0873141239397763 1.2763243912515005 0.3382949768841558 0.12874444852056108 0.17683676558437095 39.97859136303306 0.04669803140205564 0.04375579082495505 1.7287853966550187e-07 6.762258914668851 0.1890102673117242 IEDFLER ddPTM_PC-9_AZD4547_30min_R2 1 IEDFLER 7 0 P46781;B5MCT8;C9JM19 P46781 RPS9 40S ribosomal protein S9 0 116.9 0.034976 5399400.0 17979.0 23524.0 24528.0 35041.0 31612.0 30902.0 18844.0 29559.0 26810.0 24150.0 False True 23695.948013568493 31127.67296310751 24202.742693689503 26962.83882805326 27223.21946283951 28969.69305491981 20521.079494334874 24991.335748246718 28227.12186630023 23304.515850687898 1.016796408275053 1.3356927542516912 1.0385430381285992 1.1569791451924702 1.168152114262264 1.2430935377730532 0.8805623607807813 1.0723816752240758 1.211229705313403 1.0 14.508321920872262 -7.228031257380127 24.9760274967871 1.0470750634830057 1.1625971728040023 0.20501580744853276 0.11431588163320924 1040.3841491790165 777795.7570818757 0.042468025754487194 0.03289330986366111 5.915190593737165e-08 7.228031257380127 0.1155221093209966 IEDFLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IEDFLER 7 0 P46781;B5MCT8;C9JM19 P46781 RPS9 40S ribosomal protein S9 0 129.68 0.020334 4098200.0 24639.0 28878.0 35020.0 27394.0 33588.0 28505.0 27931.0 36011.0 24222.0 18338.0 False True 28809.896057567654 31744.816991946755 35855.00961408956 25859.202992546303 27006.672513475456 27010.14761981539 25285.17347707164 35065.74940680842 24576.200926478057 21662.534236471878 1.3299411667662688 1.4654248965248007 1.6551622826161625 1.1937293536510032 1.2466995882691316 1.246860008389049 1.167230629669383 1.6187279394010314 1.134502577500864 1.0 14.402914409038722 -14.221648685511147 0.10374828757879069 8.071625728177903e-13 1.5644413203268004 0.31370779956339956 0.16725731089875215 222.21591161748736 1.6530414348548295 49.0302629926825 2.664747805693409 6.002764624491259e-15 14.221648685511147 1.5644413203259933 IEDILEVIEK ddPTM_PC-9_Lapatinib_30min_R1 1 IEDILEVIEK 10 0 A0A087WYM2;A0A087X297;Q16719-2;Q16719;A0A087WYQ7 A0A087WYM2 KYNU Kynureninase 0 159.83 0.0022992 3293900.0 21926.0 18898.0 22457.0 22140.0 20990.0 15624.0 21994.0 21065.0 21719.0 22293.0 False True 21613.33121926404 18854.24284208966 20610.672146526875 23768.249456874888 19755.409467927762 14955.797941322873 23132.741702531504 22043.756801563282 19272.777508790772 26146.315346444706 0.8266300980800705 0.7211051573526364 0.7882820915081424 0.909047762254073 0.7555714526564846 0.5720040374008767 0.8847419376695088 0.843092286981107 0.7371125626468596 1.0 14.674320029426669 -14.522837856179706 0.5274281374538341 9.380849391268955 0.7806620275094095 0.33888483307000605 0.09118578408490136 4276.685436701547 17.787698958763933 42505.71478408388 0.04242336055168977 3.000282465197672e-15 14.522837856179706 -8.600187363759545 IEDLSQQAQLAAAEK ddPTM_PC-9_Lapatinib_30min_R1 4 IEDLSQQAQLAAAEK 15 0 E9PAV3;F8VZJ2;F8W0W4;H0YHX9;Q13765;E9PAV3-2;F8W1N5;F8VNW4 E9PAV3 NACA Nascent polypeptide-associated complex subunit alpha, muscle-specific form;Nascent polypeptide-associated complex subunit alpha 0 ;;; 232.53 2.1406999999999993e-92 14971600.0 110627.0 105499.0 111417.0 106701.0 107212.0 92011.0 100667.0 97176.0 91598.0 100084.0 False True 109049.43869349257 105254.7235473395 102256.72434205763 114548.14748410143 100906.00094690196 88075.90401811706 105879.04469258615 101691.15171842925 81281.26867029862 117383.38604645267 0.929002326192379 0.8966747943843311 0.8711345598907081 0.9758463385846678 0.8596276214674022 0.7503268306066957 0.9019934443762437 0.8663163940268901 0.6924426991578929 1.0 16.84086870431119 -6.509507210609718 24.292557238146834 0.8339723582849876 0.9138285952916203 0.15983846505955934 0.08152231440825615 757.7698428220108 1376671.7043326506 0.024745449334302005 0.02683552595805111 3.0938039484669454e-07 6.509507210609718 0.07985623700663269 IEDS(ph)EPHIPLIDDTDAEDDAPTKR ddPTM_PC-9_AZD4547_30min_R2 1 IEDSEPHIPLIDDTDAEDDAPTKR 24 1 A0A0U1RQU3;E7ERY9;P20020-6;P20020;P20020-4;P20020-1;H0YHH6 A0A0U1RQU3 ATP2B1 Calcium-transporting ATPase;Plasma membrane calcium-transporting ATPase 1 1 IEDS(1)EPHIPLIDDTDAEDDAPTKR 79.332 5.8682e-05 1458800.0 10712.0 20478.0 18984.0 16955.0 17501.0 15368.0 15949.0 21362.0 16526.0 13553.0 True False 14118.193176558536 27097.113030884033 18732.25975607475 13046.286702138725 15071.288239249474 14407.0365305808 17368.430102693022 18060.993749925445 17399.530621502323 13078.513595212147 1.0794952403250933 2.071880174579158 1.4322927158123195 0.9975358902340996 1.1523701167972829 1.1015805753227956 1.3280125433406553 1.3809668521151601 1.3303905290790872 1.0 13.674910963912101 -5.526519272691001 24.26024847966657 1.2025125503227736 1.6197873770012854 0.28014004466363507 0.2561212106679827 77.38117930724569 515661.3696300874 0.06647694244625 0.11590190338374615 2.974957236241513e-06 5.526519272691001 0.4172748266785118 IEDS(ph)EPHIPLIDDTDAEDDAPTKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IEDSEPHIPLIDDTDAEDDAPTKR 24 1 A0A0U1RQU3;E7ERY9;P20020-6;P20020;P20020-4;P20020-1;H0YHH6 A0A0U1RQU3 ATP2B1 Calcium-transporting ATPase;Plasma membrane calcium-transporting ATPase 1 1 IEDS(1)EPHIPLIDDTDAEDDAPTKR;IEDS(1)EPHIPLIDDTDAEDDAPTKR 59.792 0.0016899999999999999 4408900.0 12255.5 10573.0 14266.5 11351.0 23199.0 11364.9 10963.7 9884.6 9792.2 10252.3 True False 14330.114092841446 11622.617565477278 14606.667466002547 10715.040270438529 18653.322485414938 10768.904637236974 9925.138965685808 9625.13972359941 9935.392399977642 12110.960832837854 1.1832351116177788 0.9596775785091737 1.206070077148445 0.8847390738301784 1.5402017018202236 0.8891866455416149 0.8195170558866499 0.7947461689002949 0.820363680232427 1.0 13.564025706495947 -6.970458664578234 24.999893036578985 0.8433804045814322 1.14008236464449 0.4171375806743506 0.17089538330584148 195.00246861755434 165023.8413568824 0.05736816381214173 0.05059336143538732 1.0703882558255896e-07 6.970458664578234 0.2967019600630578 IEDVGS(ph)DEEDDSGK ddPTM_PC-9_AZD4547_30min_R2 5 IEDVGSDEEDDSGK 14 0 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 IEDVGS(0.999)DEEDDS(0.001)GK;IEDVGS(0.845)DEEDDS(0.155)GK;IEDVGS(1)DEEDDSGK;IEDVGS(1)DEEDDSGK;IEDVGS(0.937)DEEDDS(0.063)GK 225.21 7.4476e-48 919697000.0 297529.6 425827.1 288332.9 165616.4 220571.3 353987.7 412279.7 397341.2 386741.3 258021.9 True False 392137.82379986893 563467.3825722019 284509.41735263006 127436.0977278729 189948.78233277946 331852.7931595711 448971.79460839165 335941.24753243517 407183.6555699873 248988.6318167535 1.5749226016409776 2.2630245343365445 1.1426602703773985 0.5118149242318066 0.7628813450108629 1.332802990795992 1.8031819016493027 1.3492232359414529 1.6353503876821955 1.0 17.92572034847315 -7.008975147965338 24.701278233450413 1.4891767788952215 1.2389547916373418 0.032494829715709606 0.48011363360103915 1422.5467876636228 3915116.462137393 0.19697198793054607 0.1647950138432235 9.79546037273453e-08 7.008975147965338 -0.2502219872578797 IEDVGS(ph)DEEDDSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IEDVGSDEEDDSGK 14 0 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 IEDVGS(1)DEEDDSGK;IEDVGS(1)DEEDDSGK;IEDVGS(1)DEEDDSGK;IEDVGS(1)DEEDDSGK 238.88 3.967800000000001e-27 110127000.0 170247.9 412504.0 225904.7 184911.3 196692.0 116052.1 213934.0 108351.3 111072.7 129354.7 True False 199067.5069207019 453454.6709760379 231291.12479634516 174551.31935152307 158151.6145653365 109966.12357795399 193668.62277196787 105507.19318269198 112696.92810859653 152805.68313875838 1.3027493665921739 2.967524909163679 1.513629074818614 1.1423090801735307 1.03498516100166 0.7196468175735123 1.2674176692505805 0.6904664212448431 0.7375179102877982 1.0 17.22133867542587 -5.611102451326508 3.050743468297808 0.9295798298115825 2.1575261775642565 0.5633954964609662 0.4178110439193492 0.15814838147755683 2.937894844470753 0.11026027829340075 0.21611292445417266 2.4484855688706708e-06 5.611102451326508 1.227946347752674 IEDVGS(ph)DEEDDSGK ddPTM_PC-9_Lapatinib_30min_R1 12 IEDVGSDEEDDSGK 14 0 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 IEDVGS(0.707)DEEDDS(0.293)GK;IEDVGS(1)DEEDDSGK;IEDVGS(0.998)DEEDDS(0.002)GK;IEDVGS(0.995)DEEDDS(0.005)GK;IEDVGS(1)DEEDDSGK;IEDVGS(1)DEEDDSGK;IEDVGS(0.999)DEEDDS(0.001)GK;IEDVGS(0.985)DEEDDS(0.015)GK;IEDVGS(0.999)DEEDDS(0.001)GK;IEDVGS(0.999)DEEDDS(0.001)GK;IEDVGS(1)DEEDDSGK;IEDVGS(1)DEEDDSGK 246.77 1.3859999999999998e-36 1431310000.0 1130679.4 2078005.0 1520628.0 1526912.0 1943718.0 1457231.0 2097830.0 2203664.0 1448038.3 2012350.0 True False 1114555.70441479 2073193.5070947492 1395607.8356338288 1639206.2021091143 1829392.3287366172 1394908.6271013753 2206445.372638976 2306054.2743109544 1284944.9781347055 2360182.0162121733 0.47223294506901065 0.8784040776744803 0.5913136470184712 0.6945253335756942 0.7751064605062055 0.5910173950651683 0.9348623781906757 0.9770662849181065 0.5444262219220268 1.0 21.17046669321673 -7.264444573825232 24.911501662821305 0.8621775792603307 0.6794158676879556 0.2726929996329829 0.15682021724681822 368.8828956231231 3057825.2817744864 0.060537445214577254 0.042800015997440176 5.439455475165331e-08 7.264444573825232 -0.18276171157237509 IEDVGS(ph)DEEDDSGKDK ddPTM_PC-9_AZD4547_30min_R2 13 IEDVGSDEEDDSGKDK 16 1 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(0.998)DEEDDS(0.002)GKDK;IEDVGS(0.999)DEEDDS(0.001)GKDK 211.45 5.8374e-17 3338169800.0 877711.7 1109752.0 713966.1 559964.2 691588.4 931864.0 1074831.0 898915.0 1030103.2 822011.6 True False 1156805.7630625092 1468457.631616837 704498.4430168368 430873.1050506491 595573.2883447431 873594.3967681623 1170488.876776451 760008.3417617365 1084552.352154636 793233.224084859 1.458342550385605 1.851230617969859 0.8881353196339019 0.543185902919965 0.750817376606794 1.1013083797341126 1.4755923494339587 0.9581146107924898 1.3672553282243913 1.0 19.597385579661974 -7.029163239586843 24.590168680060742 1.2098501435570772 1.08049058797275 0.016268917644107428 0.37067462454590017 3283.4545252116327 2768567.965426326 0.15946785127033603 0.12376149373366331 9.350541464429087e-08 7.029163239586843 -0.1293595555843272 IEDVGS(ph)DEEDDSGKDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 15 IEDVGSDEEDDSGKDK 16 1 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 IEDVGS(0.999)DEEDDS(0.001)GKDK;IEDVGS(0.994)DEEDDS(0.006)GKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(0.999)DEEDDS(0.001)GKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(0.878)DEEDDS(0.122)GKDK 241.66 3.7232e-37 1497830000.0 625510.5 896309.9 505813.1 615722.2 622443.2 452197.3 728280.0 462459.8 462908.39999999997 474144.9 True False 731397.0732544798 985289.6233662344 517873.60261086497 581225.2813323061 500479.9232058968 428483.2775401488 659292.0461094017 450320.72026666143 469677.559613346 560103.6170410356 1.3058245849551344 1.7591202652312954 0.9246032106465104 1.0377102801136224 0.8935488148601431 0.7650071602889797 1.1770894278318849 0.8039953797221578 0.8385547697310004 1.0 19.09533421939824 -5.274989517279409 24.807861681660903 0.9285313327268377 1.5324724089268922 0.7135082862546205 0.1526865476203712 297.612888640748 544875.760852006 0.03806377291863296 0.07994790825954645 5.3089725853255295e-06 5.274989517279409 0.6039410762000544 IEDVGS(ph)DEEDDSGKDK ddPTM_PC-9_Lapatinib_30min_R1 18 IEDVGSDEEDDSGKDK 16 1 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 IEDVGS(0.999)DEEDDS(0.001)GKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(0.998)DEEDDS(0.002)GKDK;IEDVGS(0.999)DEEDDS(0.001)GKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(0.997)DEEDDS(0.003)GKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(0.999)DEEDDS(0.001)GKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(0.81)DEEDDS(0.19)GKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK 203.53 3.7385e-16 9312834900.0 827380.5 1193722.0 740716.9 868695.4 999286.0 899011.9 988463.9 1004507.4 802900.3 941834.7 True False 815581.902346999 1190958.0100510598 679818.01573192 932582.1575989026 940509.962151867 860563.2567360961 1039641.7241509923 1051180.4809385545 712469.2132990177 1104629.572979149 0.7383306787155824 1.0781514809884059 0.6154262318891877 0.8442487693714009 0.8514256590246295 0.77905143750152 0.941167744900323 0.9516135604658456 0.6449847358128501 1.0 20.07513122598054 -7.250772649735328 24.402892886575366 0.8804093105980122 0.8231434091738555 0.050267686857375926 0.14037324064779858 2139.564659255427 4894815.609671251 0.052193455769151215 0.03997557487294508 5.6134175779560153e-08 7.250772649735328 -0.05726590142415666 IEDVGS(ph)DEEDDSGKDKK ddPTM_PC-9_AZD4547_30min_R2 4 IEDVGSDEEDDSGKDKK 17 2 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 IEDVGS(0.996)DEEDDS(0.004)GKDKK;IEDVGS(1)DEEDDSGKDKK;IEDVGS(0.996)DEEDDS(0.004)GKDKK;IEDVGS(0.997)DEEDDS(0.003)GKDKK 93.34200000000001 0.0053212 127402000.0 229173.0 234066.0 160310.0 122729.0 156198.0 228702.0 240047.0 179302.0 234270.0 198185.0 True False 302045.2469054753 309723.25708989636 158184.1846553068 94435.72519414827 134512.60387373835 214401.22778610667 261410.71796734238 151594.99585006706 246653.03392831617 191246.60347281935 1.5793496010945 1.6194967725736125 0.827121537234456 0.493790339171016 0.703346367627678 1.1210720812439325 1.366877702507773 0.7926676505479078 1.2897119710853917 1.0 17.54507460029997 -5.256607299384385 24.804930241197724 0.9379113195304974 1.5994232799120065 0.51666173074702 0.25132029995332955 298.6540686738804 1533091.766513356 0.07042005652422162 0.17411683702865893 5.538506893793245e-06 5.256607299384385 0.6615119603815091 IEDVGS(ph)DEEDDSGKDKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IEDVGSDEEDDSGKDKK 17 2 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 IEDVGS(0.995)DEEDDS(0.005)GKDKK;IEDVGS(1)DEEDDSGKDKK;IEDVGS(1)DEEDDSGKDKK;IEDVGS(0.995)DEEDDS(0.005)GKDKK 83.891 0.0098899 244530000.0 284994.0 342928.0 221854.0 270619.0 279433.0 217456.0 313761.0 210540.0 221263.0 239339.0 True False 333237.85531192203 376971.6255078026 227143.84074598033 255457.09478863553 224680.1095765744 206052.2245505903 284039.28664707585 205013.54808556923 224498.55278652936 282729.2660935183 1.1786464836706965 1.3333307538919998 0.8033969878125317 0.9035396240307788 0.7946828875587892 0.7287969420273402 1.0046334805436246 0.7251231926508696 0.7940407298064149 1.0 18.109061702716083 -5.265125471594449 24.989877981705927 0.8364077640897248 1.2559886364246766 0.7300097497484148 0.10006129232030805 132.0319007576543 895117.3876666945 0.02479145317611589 0.05503948223554265 5.430934042398733e-06 5.265125471594449 0.4195808723349518 IEDVGS(ph)DEEDDSGKDKK ddPTM_PC-9_Lapatinib_30min_R1 4 IEDVGSDEEDDSGKDKK 17 2 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 IEDVGS(0.98)DEEDDS(0.02)GKDKK;IEDVGS(0.999)DEEDDS(0.001)GKDKK;IEDVGS(0.988)DEEDDS(0.012)GKDKK;IEDVGS(0.998)DEEDDS(0.002)GKDKK 82.48299999999999 0.012442 3080400000.0 312096.0 520138.0 203198.0 283124.0 301354.0 283536.0 297682.0 296684.0 240702.0 280736.0 True False 307645.45380860294 518933.6524181838 186491.84480696308 303945.8834339775 283628.95020475984 271409.82623469835 313094.5173907875 310469.0217381914 213591.60605557178 329260.8435427932 0.934351775626849 1.5760563777780012 0.5663954535265753 0.9231157891827317 0.8614111145223295 0.8243003428964487 0.9509011579449939 0.9429272500112531 0.6487002941417535 1.0 18.32887142795675 -5.265041624834848 24.99990348707346 0.8448539288186278 1.2552040674414233 0.4248292201835021 0.19330393602843196 250.21072499087893 1736497.5871875263 0.0465144357015661 0.10330894020635523 5.4319826630935575e-06 5.265041624834848 0.41035013862279557 IEDVGSDEEDDS(ph)GKDKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IEDVGSDEEDDSGKDKK 17 2 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 IEDVGS(0.091)DEEDDS(0.909)GKDKK 69.878 0.043519999999999996 56867000.0 61274.0 83814.0 48291.0 72000.0 62020.0 41264.0 71075.0 52099.0 48269.0 53580.0 True False 71646.47798333535 92134.50001257096 49442.44058463737 67966.07342714947 49867.62621429522 39100.04319887959 64342.26146156113 50731.456453453415 48974.842809023605 63293.62986095334 1.1319698070837771 1.45566781704536 0.7811598211898264 1.0738217033287678 0.7878774897860488 0.6177563727151777 1.0165677273196605 0.8015254704920993 0.7737720670565746 1.0 15.949772687568538 -5.268707686955106 24.981513001114397 0.8519639447233479 1.2938188195545794 0.5779700909196308 0.14941609494780417 328.1919759018675 1128014.0994331199 0.038069227968189026 0.08192239076129446 5.386322007589973e-06 5.268707686955106 0.44185487483123154 IEDVTPIPSDS(ph)TR ddPTM_PC-9_AZD4547_30min_R2 2 IEDVTPIPSDSTR 13 0 P62263;A0A2R8Y811 P62263 RPS14 40S ribosomal protein S14 1 IEDVTPIPSDS(0.981)T(0.019)R;IEDVTPIPSDS(0.999)T(0.001)R 188.09 3.0517e-05 15973300.0 57468.0 64710.0 75504.0 123744.0 115994.0 79404.0 56757.0 85299.0 82113.0 79117.0 True False 75741.62859134308 85626.24202698043 74502.76762656274 95216.73262574195 99890.23530218299 74438.85532757937 61808.263047121865 72117.99952602257 86453.32554298804 76347.13791134061 0.9920689977835097 1.1215383362034517 0.9758423126886605 1.2471552337209282 1.3083690893322313 0.9750051850538618 0.8095688291406253 0.9446064580675021 1.1323715322948111 1.0 16.22028645407635 -6.963351080740466 24.94233007860188 0.956344206046964 1.1281417344364388 0.2971469539224826 0.11957125690797116 210.0393164500008 142946.87567733836 0.044533254510422185 0.03927453185410673 1.0880501652760919e-07 6.963351080740466 0.17179752838947482 IEDVTPIPSDS(ph)TR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IEDVTPIPSDSTR 13 0 P62263;A0A2R8Y811 P62263 RPS14 40S ribosomal protein S14 1 IEDVTPIPSDS(0.984)T(0.016)R 163.33 0.00034487 5155400.0 20915.0 20767.0 28196.0 26604.0 37610.0 30167.0 24391.0 34492.0 22695.0 15709.0 True False 24455.496409920343 22828.61051567831 28868.299573925484 25113.46413133173 30240.590485644036 28584.989414031617 22080.507904452188 33586.62154729488 23026.871440278243 18556.91734762443 1.317864166326689 1.2301941151125901 1.5556624536898673 1.3533209024367747 1.62961282411032 1.5403953619317563 1.1898801665611143 1.809924618303831 1.2408780515060083 1.0 14.179669451185902 -8.525271894683955 24.82889687656608 0.9999999786820719 1.4509510128235985 0.3891110855632859 0.1799672779989128 219.24021196718664 2274622.2981110467 0.16764706052864747 0.04328628482350546 2.983514173287752e-09 8.525271894683955 0.4509510341415266 IEDVTPIPSDS(ph)TR ddPTM_PC-9_Lapatinib_30min_R1 2 IEDVTPIPSDSTR 13 0 P62263;A0A2R8Y811 P62263 RPS14 40S ribosomal protein S14 1 IEDVTPIPSDS(0.889)T(0.111)R;IEDVTPIPSDS(0.866)T(0.134)R 148.41 0.00011554 12251000.0 63342.0 51917.0 69651.0 66727.0 80728.0 49489.0 56288.0 77485.0 81537.0 74366.0 True False 62438.73146449985 51796.78937627098 63924.56364063518 71634.32617474657 75979.73775735451 47372.47083449363 59202.31722070076 81085.23597289975 72353.44443732564 87220.06401353366 0.7158757812286337 0.5938632350491492 0.7329112213299478 0.8213055904617463 0.8711268286338907 0.5431373087176707 0.6787694768432471 0.9296626514779674 0.8295504624497729 1.0 16.412372428808382 -7.763214429579823 24.999801443113995 0.9097049672357442 0.7089735480876806 0.49353066389147626 0.09806804974664504 45.00866392917983 633863.6689289259 0.05344263793022334 0.027759405229454123 1.724985983055863e-08 7.763214429579823 -0.20073141914806358 IEDVTPIPSDS(ph)TRR ddPTM_PC-9_AZD4547_30min_R2 2 IEDVTPIPSDSTRR 14 1 P62263;A0A2R8Y811 P62263 RPS14 40S ribosomal protein S14 1 IEDVTPIPSDS(0.95)T(0.05)RR;IEDVTPIPSDS(0.709)T(0.291)RR 143.64 0.00024649 6847600.0 29888.0 32310.0 41540.0 72147.0 65600.0 37518.0 31260.0 47573.0 34122.0 40177.0 True False 39391.76229098032 42753.57564351314 40989.15245824618 55514.623810038545 56492.57233842442 35171.993529042855 34042.0794413558 40221.685968785816 35925.61925855636 38770.415458927055 1.0160263134840923 1.1027371034701912 1.05722757863324 1.4318810658309844 1.4571051578818395 0.9071863974814424 0.878042678635198 1.0374324208982548 0.9266245623964376 1.0 15.242668574461145 -6.798209009121532 24.99998558878536 0.9477081302979062 1.2103768271934434 0.4632817383083079 0.14158990829295756 176.9971669903404 120340.70543247803 0.05538025608377382 0.04884214972517409 1.591442642987246e-07 6.798209009121532 0.2626686968955372 IEDVTPIPSDS(ph)TRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IEDVTPIPSDSTRR 14 1 P62263;A0A2R8Y811 P62263 RPS14 40S ribosomal protein S14 1 IEDVTPIPS(0.001)DS(0.868)T(0.131)RR;IEDVTPIPSDS(0.643)T(0.357)RR 121.45 0.00049263 0.0 16174.5 17757.5 22081.0 23061.0 27100.0 23511.0 20652.6 32942.0 20802.3 20002.4 True False 18912.52338906318 19520.347244770903 22607.494782658825 21768.966934770757 21789.949538977748 22278.04177124996 18696.236216124358 32077.30740493413 21106.494283414864 23628.67678108873 0.8004055226740359 0.8261295131174702 0.9567820911898373 0.9212943719384915 0.9221823862950036 0.9428391601293664 0.7912519346444291 1.357558347516408 0.8932575649055177 1.0 14.528251219406581 -7.722240241270319 24.999999938328827 1.0940582486262436 0.8866108584186915 0.36630858635969565 0.1222035902225399 148.5809425503839 94760.27201069114 0.05381850994192118 0.031071508448447707 1.8956569992235945e-08 7.722240241270319 -0.2074473902075521 IEDVTPIPSDS(ph)TRR ddPTM_PC-9_Lapatinib_30min_R1 2 IEDVTPIPSDSTRR 14 1 P62263;A0A2R8Y811 P62263 RPS14 40S ribosomal protein S14 1 IEDVTPIPS(0.321)DS(0.55)T(0.129)RR;IEDVTPIPS(0.019)DS(0.49)T(0.49)RR 79.92 0.0055959 11126400.0 64945.0 60375.0 86397.0 70547.0 77568.0 50752.0 58805.0 71922.0 79529.0 77742.0 True False 64018.872390545606 60235.20539692896 79293.77216206456 75735.26171789317 73005.6027445555 48581.455268690435 61849.63516492518 75263.75868416969 70571.606542503 91179.60111529651 0.7021183642774859 0.6606215059085596 0.8696437711083828 0.8306162868833569 0.8006791195789504 0.5328105702859923 0.6783275470432952 0.8254451408380121 0.7739845939144357 1.0 16.47642347738733 -8.875977564670661 1.2709260651058096 0.9990426322820151 0.7332786549313156 0.4118372978103684 0.09445934596747414 1.3994041474064947 3.5908833689940414 0.09864601804252651 0.029668555315834084 1.3305231500372999e-09 8.875977564670661 -0.26576397735069945 IEDVTPIPSDSTR ddPTM_PC-9_AZD4547_30min_R2 1 IEDVTPIPSDSTR 13 0 P62263;A0A2R8Y811 P62263 RPS14 40S ribosomal protein S14 0 110.86 0.002903 2837000.0 7944.4 8387.8 15064.0 18713.0 14813.0 10115.0 8267.4 12233.0 9242.6 9464.6 False True 10470.553946214677 11098.992317631066 14864.241517357259 14399.006962967978 12756.470640992082 9482.507450990684 9003.182583924025 10342.670936374774 9731.144966858126 9133.247234800034 1.1464218231517 1.2152295927499952 1.627487041051583 1.5765484709648545 1.3967070323451478 1.0382405301435265 0.9857592105488583 1.1324199017592038 1.0654638724527183 1.0 13.15691217188499 -6.757601053938759 12.759546990910636 1.0489579646484193 1.405957504604527 0.6066805170190903 0.1399078162445592 0.1921748841573655 610.095464484247 0.052784075896422186 0.050271187796249305 1.747426614635794e-07 6.757601053938759 0.35699953995610767 IEDVTPIPSDSTR ddPTM_PC-9_Lapatinib_30min_R1 4 IEDVTPIPSDSTR 13 0 P62263;A0A2R8Y811 P62263 RPS14 40S ribosomal protein S14 0 ;;; 201.09 1.3261e-06 32635700.0 93809.0 100684.0 101035.0 103615.0 98213.0 102785.0 102422.0 93093.0 87632.0 88704.0 False True 92471.26645753652 100450.87238400643 92728.29230637834 111235.1927495072 92436.30443418732 98389.12515353767 107724.91000530514 97418.44063270501 77761.96135413012 104036.36820934975 0.8888359719695226 0.9655361304219279 0.891306510428964 1.069195269539508 0.8884999161848872 0.9457185679103265 1.0354543498532458 0.9363883256350544 0.7474497879208134 1.0 16.66672841687521 -8.02234961188319 24.992565510355224 0.8631229315056305 0.95663354779994 0.13402897940685277 0.08043829043699537 1253.7444157939026 1401997.2849521765 0.04977899861557759 0.019154934671178975 9.498398541693332e-09 8.02234961188319 0.09351061629430957 IEDVTPIPSDSTRR ddPTM_PC-9_AZD4547_30min_R2 2 IEDVTPIPSDSTRR 14 1 P62263;A0A2R8Y811 P62263 RPS14 40S ribosomal protein S14 0 ; 131.79 9.6528e-06 19083200.0 100897.0 75909.0 123571.0 207788.0 166385.0 120788.0 100852.0 136349.0 107070.0 142333.0 False True 132980.1472120262 100445.09976859922 121932.36780014295 159885.6868925983 143285.31476415799 113235.1072654732 109827.63262378785 115279.39503831965 112729.50161226287 137349.96499279377 0.9681847914486412 0.7313077930079501 0.8877495367875796 1.1640751921632226 1.0432133329751894 0.8244276383427852 0.799618934227978 0.8393114264307815 0.8207464895835784 1.0 17.067497017142323 -6.787809404759444 24.97634211091653 0.8432026972440642 0.9537069515122335 0.15753743432423972 0.11560469425246692 436.55404430836114 413478.59194637334 0.04455995929623092 0.03930947447037705 1.630011225287552e-07 6.787809404759444 0.11050425426816934 IEDVTPIPSDSTRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IEDVTPIPSDSTRR 14 1 P62263;A0A2R8Y811 P62263 RPS14 40S ribosomal protein S14 0 ; 128.35 1.6416e-05 14034000.0 54861.0 36247.0 44028.0 57522.0 71905.0 71092.0 54994.0 74565.0 54281.0 49319.0 False True 64147.88374585892 39845.362611922355 45077.79449711983 54299.228828840176 57815.7314243614 67363.81036968659 49784.570197919034 72607.747758148 55074.75693543701 58260.14429101082 1.1010594725862453 0.6839214543117815 0.7737329703811779 0.9320132912409935 0.9923719230005753 1.1562589003076054 0.8545219172346005 1.2462679013541498 0.9453247602741469 1.0 15.830221654108177 -6.145204164989377 2.664172207568879 1.044462970883772 0.8382133445056502 0.24130164323615544 0.14187975120925386 0.35071939442652644 4.842088193361502 0.04305766435811255 0.05870900437041427 7.158068251175541e-07 6.145204164989377 -0.20624962637812183 IEDVTPIPSDSTRR ddPTM_PC-9_Lapatinib_30min_R1 2 IEDVTPIPSDSTRR 14 1 P62263;A0A2R8Y811 P62263 RPS14 40S ribosomal protein S14 0 ; 119.25 6.5697e-05 20980200.0 129281.0 93584.0 122224.0 99666.0 99105.0 115943.0 81487.0 85342.0 104806.0 73154.0 False True 127437.4292327685 93367.31199778375 112175.21451828402 106995.77011602935 93275.8387479267 110984.38816633388 85705.99814104688 89307.30087628853 93001.64462389277 85798.5714284223 1.4853094534223512 1.088215228334841 1.307425201267675 1.2470577112730934 1.0871490887903923 1.2935458751655662 0.998921039291981 1.0408949635110578 1.0839532998690968 1.0 16.388666006175335 -1.5228787452805082 0.17370348036594674 0.9614816579217538 2.620625632499141 0.5200782254823839 0.10616352189627123 49.131437001282286 0.5400042941756975 0.25489107299487035 21.30169288168511 0.029999999999988217 1.5228787452805082 1.6591439745773873 IEEAMDGS(ph)ETPQLFTVLPEKR ddPTM_PC-9_Lapatinib_30min_R1 1 IEEAMDGSETPQLFTVLPEKR 21 1 E9PPJ0;Q13435 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 IEEAMDGS(0.5)ET(0.5)PQLFTVLPEKR 92.671 0.00015059 5675400.0 16717.0 11375.0 13426.0 11093.0 9429.9 10240.0 9901.9 7043.4 14647.0 8301.1 True False 16478.612514477656 11348.661886377917 12322.166105858738 11908.816225163207 8875.251821896716 9802.05907060588 10414.571931631206 7370.662077195862 12997.300620252254 9735.934074479532 1.692555885076551 1.1656469527793716 1.2656377920797972 1.2231816828319921 0.9115973623076503 1.0067918492073276 1.069704442528074 0.7570575171124386 1.3349823982807802 1.0 13.249103683738435 -1.5228787452810102 0.6244304899993959 1.0138553728384063 48.032317508005825 0.5878234382041909 0.15826847231533087 131.0469560211668 0.9303204220689872 0.0661464354740535 8464.481817603333 0.029999999999953536 1.5228787452810102 47.01846213516742 IEEAMDGSET(ph)PQLFTVLPEKR ddPTM_PC-9_AZD4547_30min_R2 5 IEEAMDGSETPQLFTVLPEKR 21 1 E9PPJ0;Q13435 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 IEEAMDGS(0.083)ET(0.917)PQLFTVLPEKR;IEEAMDGS(0.017)ET(0.937)PQLFT(0.046)VLPEKR;IEEAMDGS(0.075)ET(0.925)PQLFTVLPEKR;IEEAMDGS(0.009)ET(0.991)PQLFTVLPEKR;IEEAMDGS(0.028)ET(0.972)PQLFTVLPEKR 105.01 4.0721e-05 35033200.0 78035.9 68055.1 98726.2 136732.0 125991.0 118657.0 83502.3 103409.0 80999.1 109899.0 True False 102849.6929524462 90052.58018498473 97417.02608144688 105210.54988834164 108499.32441296407 111237.3590323481 90933.8429346104 87429.51515242201 85280.54706306006 106051.46946065237 0.9698092207067993 0.8491403338677583 0.9185825201374596 0.992070646671966 1.0230817636451508 1.0488997427199236 0.8574500984953256 0.8244064471436716 0.804143002419228 1.0 16.694405085582588 -7.308550059254267 20.963719031936428 0.8568665385894418 0.9630739378577969 0.29024823396278354 0.07150838609046858 84.56625638220791 37629.732340217524 0.031556313145066135 0.02127561092122145 4.9141673344446096e-08 7.308550059254267 0.1062073992683551 IEEAMDGSET(ph)PQLFTVLPEKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IEEAMDGSETPQLFTVLPEKR 21 1 E9PPJ0;Q13435 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 IEEAMDGS(0.073)ET(0.927)PQLFTVLPEKR;IEEAMDGS(0.394)ET(0.606)PQLFTVLPEKR;IEEAMDGS(0.038)ET(0.962)PQLFTVLPEKR;IEEAMDGS(0.067)ET(0.933)PQLFTVLPEKR 95.365 0.00016195 49823500.0 169520.0 123864.0 174491.0 193593.0 215292.0 192590.0 184552.0 186490.0 173583.0 145951.0 True False 198216.38782738172 136160.3993313417 178651.52720080255 182746.61184697403 173107.0780865534 182490.24136468142 167069.89851922658 181594.83510248852 176121.32298822733 172410.7609525194 1.1496752681346207 0.7897442049388045 1.0361970808191132 1.0599489894792649 1.0040387104040784 1.0584620145313195 0.9690224531010355 1.0532685668761612 1.0215216382968682 1.0 17.395490296940032 IEEAMDGSET(ph)PQLFTVLPEKR ddPTM_PC-9_Lapatinib_30min_R1 4 IEEAMDGSETPQLFTVLPEKR 21 1 E9PPJ0;Q13435 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 IEEAMDGS(0.052)ET(0.948)PQLFTVLPEKR;IEEAMDGS(0.024)ET(0.975)PQLFTVLPEKR;IEEAMDGS(0.09)ET(0.909)PQLFT(0.001)VLPEKR;IEEAMDGS(0.033)ET(0.966)PQLFT(0.001)VLPEKR 90.581 0.00019415 15953600.0 83920.59999999999 63832.7 83481.5 64711.2 69523.8 62511.799999999996 54740.1 55138.2 78232.90000000001 54318.6 True False 82723.87685484691 63684.89930501938 76617.97331790916 69470.27751823494 65434.546773049835 59838.3160361231 57574.27453263366 57700.12206389535 69421.48697304109 63707.49763501505 1.298495152466639 0.9996452798989982 1.2026523747151265 1.0904568551135894 1.0271090405705334 0.939266464034441 0.9037283941441386 0.9057037900697906 1.0896910026314628 1.0 15.95917555052904 -6.293413069590431 2.032061523233825 0.9586720047292234 1.1505343585661436 0.49969707146066245 0.0860830053923717 0.27390158608452336 2.221562271840523 0.028706842292805075 0.03642944762358336 5.088466625735256e-07 6.293413069590431 0.19186235383692019 IEEDNLTYQHLLPES(ph)PEPSASHALSDYETSEK ddPTM_PC-9_AZD4547_30min_R2 1 IEEDNLTYQHLLPESPEPSASHALSDYETSEK 32 0 Q5JTU8;B1AMJ5;A0A0A0MRG9;Q96SN8-4;Q96SN8-3;Q96SN8-2;Q96SN8 Q5JTU8 CDK5RAP2 CDK5 regulatory subunit-associated protein 2 1 IEEDNLTYQHLLPES(0.85)PEPS(0.074)AS(0.074)HALS(0.001)DY(0.001)ETSEK 87.16 2.3453e-09 6325400.0 8404.5 6110.4 19719.0 26228.0 25735.0 22584.0 14880.0 27161.0 19575.0 22159.0 True False 11076.956175540154 8085.467304615377 19457.513175834276 20181.539818560566 22162.139468435245 21171.818909854028 16204.291173620424 22963.891547688647 20609.69453684547 21383.22015467468 0.5180209573401681 0.37812206235213724 0.9099430785021676 0.9438026486459099 1.0364266610981079 0.99011368524986 0.7578040658239181 1.073921111113305 0.9638255785501929 1.0 14.384191508162502 -5.304303878807581 5.7629324815815 0.9604844788575735 0.44736377238504643 0.8497628870931749 0.08608277863066327 0.061359359689408616 5.408946674961897 0.022564595507707477 0.049431564513912424 4.962449739549009e-06 5.304303878807581 -0.513120706472527 IEEDRCS(ph)NSADITGPSFIR ddPTM_PC-9_AZD4547_30min_R2 4 IEEDRCSNSADITGPSFIR 19 1 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 IEEDRCS(0.952)NS(0.048)ADITGPSFIR;IEEDRCS(0.99)NS(0.01)ADITGPSFIR;IEEDRCS(0.999)NSADITGPSFIR;IEEDRCS(0.983)NS(0.017)ADITGPSFIR 144.17 0.00040199 53367000.0 57525.2 76747.9 73092.3 75227.0 58846.4 85084.6 79575.7 91479.0 73003.6 69956.8 True False 75817.01700150913 101555.15778801568 72123.04834433961 57884.57739556416 50676.593122802675 79764.24651157329 86657.78314144281 77343.02252829469 76862.42125619666 67507.6337251927 1.1230880541620214 1.5043507257478796 1.0683687808986928 0.85745232355793 0.7506794465511095 1.181558915785351 1.283673835972473 1.1456929870055805 1.138573773287404 1.0 16.042763030079968 -5.374221390409175 8.823598178889533 1.052573414947768 1.3129625244633027 0.272125565927565 0.17053841030564273 0.4259273825314166 30.178984477621764 0.048940002326428776 0.10212806578091747 4.224532052871587e-06 5.374221390409175 0.26038910951553484 IEEDRCS(ph)NSADITGPSFIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 IEEDRCSNSADITGPSFIR 19 1 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 IEEDRCS(0.945)NS(0.055)ADITGPSFIR;IEEDRCS(0.996)NS(0.004)ADITGPSFIR;IEEDRCS(0.963)NS(0.037)ADITGPSFIR;IEEDRCS(0.999)NS(0.001)ADITGPSFIR;IEEDRCS(1)NSADITGPSFIR;IEEDRCS(0.999)NS(0.001)ADITGPSFIR 148.97 0.00013787 66853800.0 84906.20000000001 114606.8 96183.8 82461.3 97537.0 57176.0 88237.1 59327.1 65601.9 54398.3 True False 99279.14268610952 125984.20569404507 98477.18657109278 77841.26070414169 78425.32502521304 54177.5899074045 79878.64310671708 57769.82648725844 66561.2036808983 64260.28117329414 1.5449534436112744 1.9605299477961622 1.5324736333711968 1.2113432945340372 1.2204323353911146 0.8430960605556781 1.2430484530763888 0.8989974122812731 1.0358062938037749 1.0 15.971639672939379 -5.791949002229962 1.6797122426494346 1.0299547125384707 1.767809189339529 0.7898215767281112 0.1500478763111106 0.14997106875747684 0.8616799345329487 0.0456008952278103 0.09443001122315794 1.6145481367632653e-06 5.791949002229962 0.7378544768010582 IEEDRCS(ph)NSADITGPSFIR ddPTM_PC-9_Lapatinib_30min_R1 4 IEEDRCSNSADITGPSFIR 19 1 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 IEEDRCS(0.533)NS(0.464)ADIT(0.002)GPS(0.001)FIR;IEEDRCS(0.989)NS(0.01)ADIT(0.001)GPSFIR;IEEDRCS(0.998)NS(0.001)ADIT(0.001)GPSFIR;IEEDRCS(0.958)NS(0.042)ADITGPSFIR 138.46 0.00054454 67133600.0 55820.3 97691.9 89018.4 84435.6 100308.1 103882.4 88432.7 99277.8 88327.8 74621.6 True False 55024.29228581072 97465.70040772222 81699.65077296128 90645.27569290469 94408.17477131235 99439.59191370194 93011.31250147577 103890.60901942762 78379.39303103136 87519.84413296808 0.6287064702973285 1.1136411561661776 0.9334985863187297 1.0357111188999397 1.0787059289991294 1.1361948012912855 1.0627454084603323 1.1870520342973598 0.8955613873346288 1.0 16.41732254833812 -4.756638884217613 24.99926927611148 1.0551012351004023 0.6287058226136949 0.689057702220188 0.08466525160533317 81.28841212661122 423271.4147405914 0.020403251583877673 0.16250710457314052 1.751302290909325e-05 4.756638884217613 -0.4263954124867074 IEEDRFAFT(ph)GT(ph)AGVAGDVVAT(ph)KIVELS(ph)KK ddPTM_PC-9_AZD4547_30min_R2 1 IEEDRFAFTGTAGVAGDVVATKIVELSKK 29 3 A0A3B3IRZ5;Q8IYE1 A0A3B3IRZ5 CCDC13 Coiled-coil domain-containing protein 13 4 IEEDRFAFT(1)GT(1)AGVAGDVVAT(1)KIVELS(1)KK 40.669000000000004 0.02562 8727500.0 33900.0 24158.0 36152.0 73387.0 53728.0 45030.0 24283.0 36063.0 33163.0 43611.0 True False 44679.49483619627 31966.60106456176 35672.60085870284 56468.76096784755 46268.79461278758 42214.26698152353 26444.13995759575 30490.291995298256 34915.928476393645 42084.19216415532 1.0616693000050377 0.7595868999901799 0.8476484642869426 1.341804560429322 1.09943406855262 1.0030908236722433 0.6283627794124373 0.7245070043489625 0.8296684973825599 1.0 15.360990803599693 -7.1741983117057755 8.201016699004013 0.7730428159193713 1.0185022534119526 0.29053466456514554 0.16950272475409137 0.4175405289913381 35.68098203440088 0.06940925466972774 0.05371730123819455 6.695787901187472e-08 7.1741983117057755 0.24545943749258126 IEEEEQEPEPPEPFEYIDD ddPTM_PC-9_AZD4547_30min_R2 1 IEEEEQEPEPPEPFEYIDD 19 0 A0A087WW66;Q99460-2;Q99460 A0A087WW66 PSMD1 26S proteasome non-ATPase regulatory subunit 1 0 68.83 0.037636 997710.0 6067.8 4747.1 7767.8 10969.0 6543.7 6397.8 6537.8 8729.9 6576.3 6020.2 False True 7997.234181919516 6281.507240399915 7664.793896609646 8440.266519360637 5635.220207483957 5997.744554616728 7119.6515346031965 7380.894548145033 6923.909792217458 5809.434630406266 1.3765942283027726 1.0812596474574043 1.3193700220831355 1.4528550635865218 0.9700118111303844 1.0324145009266235 1.2255326012860748 1.2705013512870653 1.1918388333312315 1.0 12.50418205318047 -14.52287873844905 0.06976224008872368 0.378478793455363 1.4385806243313608 0.19256088871847976 0.14193639406796607 640.3640209013546 3.2054460585564635 66.26495603547046 8.268762001610822 3.000000047188864e-15 14.52287873844905 1.0601018308759977 IEEEEQEPEPPEPFEYIDD ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IEEEEQEPEPPEPFEYIDD 19 0 A0A087WW66;Q99460-2;Q99460 A0A087WW66 PSMD1 26S proteasome non-ATPase regulatory subunit 1 0 ;; 137.95 0.00058811 4393200.0 51397.0 56374.0 59059.0 65199.0 73270.0 61410.0 70153.0 64324.0 58160.0 50554.2 False True 60097.496962977544 61970.43815721332 60467.19054250478 61546.11140801001 58913.26947309593 58189.55149387346 63507.59997626321 62635.56315691159 59010.47997208998 59719.276273172996 1.0063333100031966 1.0376957328441636 1.0125238334421638 1.0305903763213833 0.9865034064312809 0.9743847401582341 1.0634355260060646 1.0488332589698284 0.9881311974070017 1.0 15.865909061374365 -7.2631434328278415 24.99996464299757 1.0291694308194292 1.009609434997449 0.08007714021978807 0.026681002470535706 370.1693963905491 5430508.590036745 0.011212656209024088 0.007927254075545096 5.4557764542779416e-08 7.2631434328278415 -0.019559995821980314 IEEEEQEPEPPEPFEYIDD ddPTM_PC-9_Lapatinib_30min_R1 2 IEEEEQEPEPPEPFEYIDD 19 0 A0A087WW66;Q99460-2;Q99460 A0A087WW66 PSMD1 26S proteasome non-ATPase regulatory subunit 1 0 ; 131.69 4.157e-06 1345500.0 32717.5 27177.9 31197.5 28942.2 29787.4 28164.9 24988.0 26712.2 30483.7 22215.9 False True 32250.942450345327 27114.971242355216 28632.56197583256 31070.705936348924 28035.363696281653 26960.35288258863 26281.756372776996 27953.346329680437 27050.304698408116 26055.888714173987 1.2377602162846715 1.0406465709076007 1.0988902466511112 1.192463871686977 1.0759703498822077 1.0347124666648821 1.0086685839458678 1.0728226020736058 1.0381647310188726 1.0 14.669321842596235 -6.511332728025555 5.021623687382813 1.0354774308832706 1.1327502158094516 0.4952777440870437 0.05259114249514207 0.17784937341344792 12.98896028790685 0.01694241519915248 0.018115559870766493 3.080826717934441e-07 6.511332728025555 0.09727278492618097 IEEELGS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 2 IEEELGSK 8 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 1 IEEELGS(1)K;IEEELGS(1)K 101.38 0.0046034 12592200.0 52229.0 67185.0 50238.0 49646.0 72309.0 55363.0 67035.0 69538.0 51952.0 57439.0 True False 51484.20488237443 67029.43726033399 46107.625564288035 53297.13245420104 68055.92678496383 52995.25354745639 70505.74429522599 72768.98934094973 46100.618681186934 67367.25461734355 0.7642318983430851 0.9949854367833687 0.6844219172383749 0.7911430079337063 1.0102226544859523 0.786661915324851 1.0465877627893483 1.080183388120666 0.6843179070164814 1.0 16.039759886672655 -6.245743305353803 24.449675136942584 0.936867699272308 0.813125284992627 0.17357926533178847 0.13446157621393257 1148.2431204046773 1788609.3557294216 0.03902343835299822 0.05018482667413678 5.678801581977688e-07 6.245743305353803 -0.12374241427968091 IEEELGSK ddPTM_PC-9_AZD4547_30min_R2 1 IEEELGSK 8 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 109.11 0.017431 13432000.0 37107.0 24144.0 41348.0 53426.0 49565.0 40218.0 34129.0 49247.0 33049.0 40409.0 False True 48906.25412645235 31948.075838346685 40799.69850369676 41109.461123471745 42683.75530417689 37703.16210221883 37166.41488336636 41637.007733479004 34795.90266912928 38994.29320954235 1.2541900391333272 0.8193013184434029 1.0462992183100424 1.054243011985451 1.0946154370540477 0.9668892291396226 0.953124465768527 1.0677718277835062 0.892333205839831 1.0 15.25097538145454 -6.790914587831 24.916251075248713 0.9788282549017036 1.040321741655752 0.11011557146753193 0.10696300506767961 581.1256308894122 491238.67147731263 0.03622273798296464 0.031949901200849666 1.6183982947760965e-07 6.790914587831 0.06149348675404842 IEEELGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IEEELGSK 8 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 92.06200000000001 0.038041000000000005 9442600.0 30802.0 34983.0 32085.0 39321.0 45513.0 31863.0 46087.0 38284.0 33798.0 29979.0 False True 36016.170232769146 38455.88104540733 32850.0280830401 37117.97185040202 36595.0543678042 30192.048188394252 41721.305719014716 37279.08556525098 34292.23181046592 35413.95538636656 1.0170050151086605 1.085896241350432 0.9276012160925267 1.0481170895892489 1.0333512302862486 0.8525466262945991 1.1781035262465012 1.0526665309914083 0.9683253801033344 1.0 15.11203036695546 -7.277011963057557 24.99855177276746 1.054162708772 0.9994780791796329 0.1014270651109237 0.07981778850417609 2127.2362166162475 3414825.4590372983 0.03311593369061298 0.022415884437326533 5.2843069544495586e-08 7.277011963057557 -0.054684629592367084 IEEELGSK ddPTM_PC-9_Lapatinib_30min_R1 2 IEEELGSK 8 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 ; 121.09 0.015607 86287000.0 168038.0 171049.0 193649.0 199973.0 185814.0 180169.0 197106.0 180429.0 170155.0 181854.0 False True 165641.7473056047 170652.94654971905 177727.92672675688 214679.68151037223 174884.78584437977 172463.59186445214 207311.1842329352 188812.390028448 150990.35208841553 213287.22159477606 0.776613554563091 0.8001086294515207 0.8332797689325326 1.0065285669961124 0.8199496647607094 0.8085978643020413 0.9719812686519274 0.8852494238364277 0.707920291517894 1.0 17.702438008356822 IEESIDR ddPTM_PC-9_AZD4547_30min_R2 1 IEESIDR 7 0 Q14566 Q14566 MCM6 DNA replication licensing factor MCM6 0 94.262 0.023291 0.0 12149.0 12601.0 16738.0 22600.0 18630.0 14941.0 15133.0 19411.0 11569.0 18989.0 False True 16012.129285101708 16674.02682401453 16516.04318358509 17389.919166519332 16043.546077208026 14006.73690808223 16479.80768349447 16411.475970405514 12180.5137214184 18324.20088980176 0.8738241509900263 0.9099456464316747 0.9013240622556703 0.9490137807972626 0.8755386482439722 0.764384596759011 0.8993465953904829 0.895617553480285 0.6647227780719978 1.0 14.161462663995419 -6.524463013218065 24.995440269404373 0.839283441123907 0.9086340714537378 0.11027347732962911 0.08461063581932672 108.5391378890536 1712407.1362431566 0.026553454307832375 0.026747195930775194 2.9890762014301655e-07 6.524463013218065 0.0693506303298308 IEESIDR ddPTM_PC-9_Lapatinib_30min_R1 2 IEESIDR 7 0 Q14566 Q14566 MCM6 DNA replication licensing factor MCM6 0 ; 137.18 1.3453e-08 0.0 35910.0 35318.0 38137.0 32203.0 39220.0 38251.0 37177.0 30996.0 37969.0 29924.0 False True 35397.91681491253 35236.22334093145 35001.52307307724 34571.316046058826 36913.156709486764 36615.09389743609 39101.843151541936 32436.187316461197 33692.53138870468 35096.32352877636 1.008593301400612 1.0039861671562373 0.9972988493902676 0.9850409550080917 1.051767051304412 1.0432743437475567 1.114129322391314 0.9242047045145897 0.9600017324059406 1.0 15.099032290290085 -7.798262729935784 24.9999847433785 0.9565774104580236 1.0266785386701043 0.38944279263503667 0.03864796224141803 187.67271819491677 127411.80785681182 0.022205091171149435 0.010667362184350885 1.591245798885473e-08 7.798262729935784 0.0701011282120807 IEEVLSPEGSPS(ph)KSPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IEEVLSPEGSPSKSPSK 17 1 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 IEEVLSPEGS(0.007)PS(0.624)KS(0.326)PS(0.043)K;IEEVLSPEGS(0.023)PS(0.812)KS(0.142)PS(0.023)K 95.814 0.0007612 94824000.0 202897.0 243070.0 200672.0 248760.0 250056.0 168721.0 254540.0 155438.0 174265.0 167887.0 True False 237243.45470158235 267200.3832063337 205456.78153279846 234822.78369080165 201059.3218420158 159872.97374365476 230428.1284899867 151357.9172001743 176813.2959480098 198323.58410723897 1.1962442881896402 1.347295050203667 1.0359674693136969 1.1840386242910301 1.0137943137075294 0.806121846089707 1.1618796096655248 0.7631866773763575 0.8915394341219752 1.0 17.597496723619386 -5.9862955837052345 0.8620741651420175 0.9114619573427025 1.2746394961497065 0.5050959360573452 0.12388539231005438 0.5540793025163349 0.8242655525749009 0.056720145817967756 0.1347755085534162 1.0320587406443059e-06 5.9862955837052345 0.363177538807004 IEEVLSPEGSPS(ph)KSPSKK ddPTM_PC-9_AZD4547_30min_R2 1 IEEVLSPEGSPSKSPSKK 18 2 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 IEEVLS(0.006)PEGS(0.224)PS(0.3)KS(0.264)PS(0.205)KK 44.567 0.035011 27357000.0 49539.0 67652.0 53324.0 54328.0 69131.0 74548.0 70420.0 69285.0 76148.0 72058.0 True False 65291.371524788345 89519.1859930347 52616.888918717355 41803.51895923282 59533.35393792099 69886.5017752301 76687.24357838382 58578.59526091114 80173.02782077697 69535.27135274815 0.9389676671220456 1.2873924880354515 0.7566935153210967 0.6011843794664457 0.8561605179609058 1.0050511116969716 1.1028538766945217 0.8424299513227688 1.1529836047387252 1.0 16.085457341525903 -6.79938513977826 8.34927922208665 1.0163512710602811 0.8870648790562671 0.12073924148277349 0.17872226872578387 0.6701045166307084 130.9895954361423 0.0684956345511632 0.06088530844449895 1.5871386226250756e-07 6.79938513977826 -0.12928639200401404 IEEVLSPEGSPS(ph)KSPSKK ddPTM_PC-9_Lapatinib_30min_R1 1 IEEVLSPEGSPSKSPSKK 18 2 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 IEEVLS(0.001)PEGS(0.125)PS(0.402)KS(0.402)PS(0.07)KK 48.131 0.027134 17707000.0 58816.0 78031.0 62628.0 55076.0 72776.0 72816.0 71229.0 76225.0 57920.0 56357.0 True False 57977.27305446661 77850.32401371052 57478.96759107117 59126.47276815004 68495.45876312107 69701.8294223865 74916.88909382632 79766.69177304339 51396.43967536082 66098.2323590177 0.8771380260149552 1.1777973666657289 0.8695991638455576 0.8945242657473803 1.0362676325606206 1.0545188113926494 1.133417436746408 1.2067900899343933 0.7775766134894055 1.0 16.012324070329647 -6.4581391025486985 9.849126199390158 1.0526789767331897 0.9645857893751748 0.07042352195089452 0.13257694206731774 1.4684776194670326 217.64222187754487 0.04081594921534492 0.04622259064337956 3.482257620431002e-07 6.4581391025486985 -0.08809318735801486 IEEVLSPEGSPSKS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 6 IEEVLSPEGSPSKSPSK 17 1 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 IEEVLSPEGSPS(0.004)KS(0.498)PS(0.498)K;IEEVLSPEGSPS(0.017)KS(0.611)PS(0.372)K;IEEVLSPEGSPS(0.002)KS(0.998)PSK;IEEVLSPEGS(0.019)PS(0.074)KS(0.661)PS(0.245)K;IEEVLSPEGS(0.07)PS(0.415)KS(0.465)PS(0.05)K;IEEVLSPEGS(0.001)PS(0.141)KS(0.795)PS(0.063)K 228.26 1.7304e-28 197757000.0 430671.0 657583.0 531190.0 548689.0 615645.0 705355.0 711306.0 650206.0 639945.0 599100.0 True False 567615.4194867096 870133.845013567 524146.0735266201 422197.2282105448 530173.3185562384 661249.0403453828 774610.8560176904 549731.6029474789 673771.1862263891 578125.6913518477 0.9818200920278052 1.505094580693877 0.9066299619049872 0.7302862241311384 0.9170554543537394 1.143780756048335 1.3398658243441766 0.9508859598715045 1.1654406581566905 1.0 19.14102366020162 -6.793923125924422 24.769403048098564 1.1306670398552525 1.0147038032585438 0.0650224885193279 0.20933547559768054 588.2792014292322 448568.5147272176 0.07953126036785689 0.07014523751750328 1.6072257214145748e-07 6.793923125924422 -0.11596323659670871 IEEVLSPEGSPSKS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IEEVLSPEGSPSKSPSK 17 1 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 IEEVLSPEGS(0.048)PS(0.171)KS(0.782)PSK;IEEVLSPEGS(0.001)PS(0.153)KS(0.838)PS(0.008)K;IEEVLSPEGS(0.001)PS(0.051)KS(0.747)PS(0.202)K 143.99 0.00019546 54685200.0 228547.0 321987.0 267042.0 326526.0 336271.0 247123.0 317236.0 205635.0 231981.0 250783.0 True False 267235.49309099 353951.74142204906 273409.29404242523 308231.8068315749 270381.11149157083 234163.43484482192 287185.109490254 200237.29913829255 235373.28326006522 296247.97270286403 0.9020669091937602 1.1947819868359462 0.9229068862410548 1.0404520375932855 0.9126851030395485 0.7904305055943361 0.9694078473181653 0.6759111203745859 0.7945144100484496 1.0 18.176445755767432 -6.459805797906486 3.2522049147634906 0.8335142145071948 1.0213605073227725 0.3242333977545606 0.11371418196809259 0.2714043855418015 5.6515706297613635 0.03658400787438996 0.04050622915966024 3.468919343477896e-07 6.459805797906486 0.18784629281557774 IEEVLSPEGSPSKS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 5 IEEVLSPEGSPSKSPSK 17 1 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 IEEVLSPEGSPS(0.01)KS(0.821)PS(0.168)K;IEEVLSPEGS(0.053)PS(0.261)KS(0.622)PS(0.064)K;IEEVLSPEGSPS(0.019)KS(0.979)PS(0.002)K;IEEVLSPEGS(0.012)PS(0.222)KS(0.754)PS(0.012)K;IEEVLSPEGSPS(0.057)KS(0.936)PS(0.007)K 202.35 1.6531e-12 139161000.0 398337.0 584677.0 448447.0 410330.0 509927.0 504139.0 542191.0 573112.0 421358.0 426975.0 True False 392656.6413339398 583323.2163289478 411577.4187154797 440507.03702075226 479934.09641505487 482578.1501754086 570262.9970190622 599740.8757682204 373900.224943555 500777.0598415738 0.7840947056523734 1.1648361378883616 0.8218775413667844 0.8796469973287342 0.9583787575391076 0.9636586594603143 1.138756230565895 1.1976205059352256 0.746640081839696 1.0 18.933808949625018 -7.023081482930165 15.617878023268242 1.0392224603200029 0.9307426472668568 0.08563450732182554 0.14617498932988396 15.93948861331828 10783.053525676105 0.0538135229344459 0.042438236807241715 9.482405364116479e-08 7.023081482930165 -0.10847981305314602 IEEVLSPEGSPSKS(ph)PSKK ddPTM_PC-9_AZD4547_30min_R2 1 IEEVLSPEGSPSKSPSKK 18 2 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 IEEVLSPEGS(0.003)PS(0.147)KS(0.491)PS(0.36)KK 69.765 0.030014999999999997 10313000.0 18656.0 24060.0 22159.0 23534.0 25636.0 25028.0 20119.0 24589.0 27686.0 25879.0 True False 24588.219931093732 31836.92448105624 21865.157181566614 18108.599896675474 22076.88390957086 23462.995203499228 21909.552024332603 20789.335049008365 29149.425437910773 24972.984086954555 0.9845927841654367 1.2748546337194555 0.8755524412074 0.7251275952294017 0.8840306722136356 0.9395351040869754 0.8773301559815498 0.8324730026904692 1.1672383779372972 1.0 14.608080602506613 -2.07099750743039 11.817975700699415 0.9469752254728454 1.1357031843676433 0.0 0.15379974713764064 0.0 0.0 0.036848014392624424 0.0 0.008491853487973397 2.07099750743039 0.18872795889479788 IEEVLSPEGSPSKS(ph)PSKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IEEVLSPEGSPSKSPSKK 18 2 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 IEEVLSPEGS(0.002)PS(0.043)KS(0.868)PS(0.087)KK 84.41 0.005478 12578000.0 15060.0 18808.0 18461.0 24793.0 22951.0 20762.0 18760.0 15986.0 18568.0 14012.0 True False 17609.360551441554 20675.133942258282 18901.180253732382 23403.928589990508 18453.916305132043 19673.20417058787 16982.91698936178 15566.384438567084 18839.52187279517 16552.264681069028 1.0638641231723134 1.2490818833935526 1.1419090147434525 1.413941176083161 1.1148877003059257 1.188550603174458 1.0260177272772404 0.9404383471689222 1.1381839425478797 1.0 14.01474099964086 -7.240132105465598 3.9997998458843353 1.0193008795479783 1.2037036541125807 0.41024353697291704 0.09913323384688831 0.2123788062380274 7.8710675733475925 0.04032791124790053 0.02897599233656414 5.752649242910862e-08 7.240132105465598 0.1844027745646024 IEEVLSPEGSPSKS(ph)PSKK ddPTM_PC-9_Lapatinib_30min_R1 1 IEEVLSPEGSPSKSPSKK 18 2 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 IEEVLSPEGS(0.004)PS(0.108)KS(0.545)PS(0.343)KK 75.316 0.0018834 29355000.0 50685.0 67883.0 51528.0 51189.0 63980.0 64006.0 65189.0 60627.0 58596.0 51465.0 True False 49962.22260550935 67725.82108421893 47291.566743832045 54953.609821498154 60216.822189519684 61268.61258527344 68564.1674477733 63443.95174974492 51996.301436765265 60360.65667719806 0.8277282812329502 1.1220192889286964 0.7834833043109849 0.9104210067724051 0.9976170821260679 1.0150421807524566 1.135908242589982 1.0510812049152476 0.8614270337520611 1.0 15.881320880904166 -6.369719495416129 3.8615351837573586 1.022000750164633 0.9170650569488863 0.17651119244674485 0.10396938529019625 0.4303810294974439 11.43571567956636 0.03334423205288069 0.038250802366146586 4.2685512939821217e-07 6.369719495416129 -0.1049356932157468 IEEVLSPEGSPSKSPS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 IEEVLSPEGSPSKSPSK 17 1 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 IEEVLSPEGSPS(0.01)KS(0.368)PS(0.622)K 96.455 0.00073152 81338000.0 164550.0 202820.0 193830.0 180240.0 206190.0 245480.0 241200.0 215620.0 223960.0 159110.0 True False 162203.48682522544 202350.38275122395 177894.04560543702 193495.45086301453 194062.30958513715 234981.39264182906 253688.155799336 225638.49235950992 198735.26639664712 186611.95149925133 0.8692020287129154 1.0843377453883802 0.9532832392364254 1.0368867015668652 1.0399243351030263 1.2591979814474625 1.3594421673488248 1.2091320547623938 1.0649653722604386 1.0 17.509681860500805 -6.639713225851677 4.868381986644728 1.2022594948030303 0.9960154082866752 0.4131725015774218 0.10749091407495381 0.19893521189716432 7.6397385768222055 0.03627061830358825 0.03611446044506391 2.2923808623484655e-07 6.639713225851677 -0.20624408651635506 IEEVPELPLVVEDK ddPTM_PC-9_Lapatinib_30min_R1 2 IEEVPELPLVVEDK 14 0 P36578;H3BM89 P36578 RPL4 60S ribosomal protein L4 0 ; 188.91 1.502e-05 6612900.0 31055.0 30535.0 24813.0 25563.0 30473.0 24287.7 32008.0 29961.0 27224.4 32893.0 False True 30612.150005210493 30464.298083564812 22772.970920949872 27442.988295668158 28680.638052223094 23248.971688393984 33665.217623653174 31353.097438007935 24158.101386358674 38578.51122283254 0.7935026271074145 0.7896701328778764 0.5903019634275514 0.7113542598146227 0.7434355848145994 0.6026404584175392 0.8726417001734518 0.8127088486362255 0.6262061603886051 1.0 15.235509849196713 -7.2762507769425175 24.974312433492113 0.812281576905561 0.7057944048700527 0.2363518650398927 0.10661176615707157 1407.317359293002 2372946.5119898715 0.04384549217960347 0.029701212633604035 5.2935768583501486e-08 7.2762507769425175 -0.10648717203550828 IEGEGSVLQAK ddPTM_PC-9_Lapatinib_30min_R1 1 IEGEGSVLQAK 11 0 Q14764 Q14764 MVP Major vault protein 0 125.48 0.0023857 0.0 18460.0 17739.0 23191.0 18411.0 15041.0 17872.0 17928.0 19789.0 19678.0 18840.0 False True 18196.757014850617 17697.92643538091 21284.325499848797 19765.006357295577 14156.317951743762 17107.656221666828 18856.224117622292 20708.469183296253 17461.656421473588 22096.468897277988 0.8235142501475533 0.800939123696867 0.963245557414414 0.8944870987839321 0.6406597369721659 0.7742257960399401 0.8533591591163757 0.9371845465248649 0.7902464643852959 1.0 14.431528219238139 -10.592359743108643 4.977409915957636 1.000003601261761 0.8322848887599484 0.25442765135324885 0.0868249054105271 4.027758295394135e-06 7.529602278816406e-07 0.08971077878536038 0.021757551636669 2.556467387664543e-11 10.592359743108643 -0.16771871250181258 IEHAPS(ph)PSSGGTLK ddPTM_PC-9_AZD4547_30min_R2 3 IEHAPSPSSGGTLK 14 0 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YCQ1;A0A2R8Y7Y0 Q14004 CDK13 Cyclin-dependent kinase 13 1 IEHAPS(0.966)PS(0.027)S(0.005)GGT(0.002)LK;IEHAPS(0.933)PS(0.052)S(0.011)GGT(0.004)LK;IEHAPS(0.98)PS(0.016)S(0.003)GGT(0.001)LK 112.17 0.0003295 29347000.0 134326.0 152742.0 171630.0 139057.0 158924.0 171503.0 166886.0 167126.0 170282.0 153237.0 True False 177038.8738456314 202112.8644673936 169354.07405895018 106999.55705923344 136860.14582792312 160778.89029829483 181738.53069897933 141300.5168734221 179282.75888240722 147872.21927171256 1.1972422860600045 1.3668075414220628 1.1452730938443894 0.7235947197263853 0.9255298020275535 1.0872825950009346 1.2290241642011068 0.9555582351393871 1.2124167728420872 1.0 17.173991513462532 -5.522484205438585 24.99999630981187 1.0179415953649933 1.2755288101930087 0.35698295444564354 0.14178815663199015 14.798022959315054 937668.5037683817 0.04038304312567841 0.07098589634816228 3.0027266230032037e-06 5.522484205438585 0.2575872148280154 IEHAPS(ph)PSSGGTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IEHAPSPSSGGTLK 14 0 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YCQ1;A0A2R8Y7Y0 Q14004 CDK13 Cyclin-dependent kinase 13 1 IEHAPS(0.973)PS(0.021)S(0.006)GGTLK;IEHAPS(0.818)PS(0.15)S(0.03)GGT(0.001)LK;IEHAPS(0.913)PS(0.045)S(0.014)GGT(0.028)LK 119.62 0.0014139 31007000.0 201001.0 289707.0 232066.0 215291.0 256970.0 139687.0 173481.0 130943.0 140491.0 136819.0 True False 235026.49934929007 318467.19635313784 237599.3335552055 203228.9432528395 206618.57317457985 132361.5678150905 157047.6237863254 127505.88499557691 142545.41509214035 161623.20164139214 1.4541631211511599 1.9704299451990162 1.4700818393784105 1.2574243127775784 1.278396734356389 0.8189515271994979 0.9716898452165365 0.7889082984414925 0.8819613375090701 1.0 17.302274791897062 -6.10231520752717 1.0251284775223761 0.8744161166355199 1.7275444953055983 0.7974875955482517 0.15890337679674044 0.2180576700659056 0.4731690587843702 0.0655456640113931 0.12183734158163045 7.901049678600688e-07 6.10231520752717 0.8531283786700784 IEHAPS(ph)PSSGGTLK ddPTM_PC-9_Lapatinib_30min_R1 5 IEHAPSPSSGGTLK 14 0 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YCQ1;A0A2R8Y7Y0 Q14004 CDK13 Cyclin-dependent kinase 13 1 IEHAPS(0.987)PS(0.01)S(0.003)GGTLK;IEHAPS(0.562)PS(0.147)S(0.117)GGT(0.175)LK;IEHAPS(0.914)PS(0.057)S(0.017)GGT(0.012)LK;IEHAPS(0.982)PS(0.015)S(0.003)GGTLK;IEHAPS(0.995)PS(0.002)S(0.002)GGTLK 143.46 0.00016606 34646400.0 135109.0 275174.0 300922.0 245294.0 276182.0 297032.0 258710.0 278790.0 250850.0 207963.0 True False 133182.320884044 274536.8515096397 276181.35475251183 263333.73903679627 259937.5177547035 284328.633775411 272104.737922248 291743.6011729326 222596.63143239412 243909.1274567208 0.5460325420075796 1.1255702251583573 1.1323125035635142 1.0796387235796339 1.065714598158393 1.1657154315631841 1.1155988328912794 1.19611596423221 0.912621162452773 1.0 17.895984221460445 -4.759700310225839 24.999984717723255 1.0979674779574602 0.546031854628008 0.8100895875997888 0.07861448501367009 17.142766125869546 246363.68778185337 0.01836858080380477 0.11449860981882802 1.739000431537999e-05 4.759700310225839 -0.5519356233294522 IEHAPSPS(ph)SGGTLK ddPTM_PC-9_AZD4547_30min_R2 1 IEHAPSPSSGGTLK 14 0 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YCQ1;A0A2R8Y7Y0 Q14004 CDK13 Cyclin-dependent kinase 13 1 IEHAPS(0.295)PS(0.547)S(0.141)GGT(0.017)LK 101.75 0.0016312000000000002 2243000.0 8952.2 11433.0 13255.0 13792.0 10226.0 11746.0 10935.0 19154.0 14041.0 10299.0 True False 11798.813382672446 15128.493665499407 13079.230039336853 10612.467484275869 8806.29641360866 11011.520763157348 11908.193816098072 16194.18941513303 14783.178594730369 9938.43514477162 1.187190257902878 1.5222208974677625 1.3160250933687012 1.0678207715486117 0.8860848096635664 1.107973297883848 1.1981960582962294 1.6294506307315813 1.487475480735763 1.0 13.278802994940177 -10.114849281170825 13.745923535266973 0.999999213706396 1.2627965721105037 0.12007166360365651 0.21652648080393974 0.0 0.0 0.2362427556045304 0.057297284390850446 7.676278429563057e-11 10.114849281170825 0.2627973584041077 IEHSFWR ddPTM_PC-9_AZD4547_30min_R2 1 IEHSFWR 7 0 Q16531;Q16531-2 Q16531 DDB1 DNA damage-binding protein 1 0 89.369 0.013969999999999998 7228500.0 23024.0 26822.0 34235.0 35155.0 34600.0 34304.0 28701.0 37800.0 31727.0 30445.0 False True 30345.153071049634 35491.686967202426 33781.021531248356 27050.55788933569 29796.387239473832 32158.965457121532 31255.33339879568 31958.87855758738 33404.02444804577 29379.129816736782 1.032881275256918 1.208057801187271 1.1498305682288756 0.9207406093398129 1.0142025112840254 1.094619400156676 1.0638617819439313 1.0878088887228021 1.1369984290350246 1.0 14.842504044753705 IEHSFWR ddPTM_PC-9_Lapatinib_30min_R1 1 IEHSFWR 7 0 Q16531;Q16531-2 Q16531 DDB1 DNA damage-binding protein 1 0 173.59 5.9575e-05 3592100.0 18373.0 24142.0 25907.0 24253.0 28193.0 25256.0 27511.0 24398.0 25126.0 22770.0 False True 18110.99765080445 24086.100682280074 23777.026463911978 26036.646525636275 26534.743169570625 24175.859754611552 28935.384967643164 25531.620149277995 22296.04529149026 26705.76416088214 0.6781681116368479 0.9019064400171977 0.8903331251138623 0.9749448234764999 0.9935961019395947 0.9052674774243562 1.0834883732713745 0.9560340604923038 0.8348776375457133 1.0 14.704863545761977 -4.184013199925985 1.150600050410596 0.9633652817946948 8.621765563186149e-20 0.6300172806380718 0.06378943360297877 3.5130319774045935 1.4874868385815696 0.01927534051731357 5.701040379759348 6.546162773886686e-05 4.184013199925985 -0.9633652817946948 IEHYFS(ph)PVSK ddPTM_PC-9_AZD4547_30min_R2 2 IEHYFSPVSK 10 0 E9PNQ0;E9PR18;Q96PZ2 E9PNQ0 FAM111A Protein FAM111A 1 IEHYFS(1)PVSK;IEHY(0.005)FS(0.992)PVS(0.003)K 107.85 0.0065551 7651800.0 98838.0 81412.0 98776.0 125268.0 112300.0 93475.0 80939.0 119608.0 89430.0 97216.0 True False 130266.42804188692 107726.83690156888 97466.16570090815 96389.3979713073 96709.08343910145 87629.99347319377 88142.41420038037 101125.33191841046 94157.08722503656 93812.4974302476 1.3885828819208645 1.1483207445966035 1.0389464982890704 1.0274686274392781 1.030876334051415 0.9340972245019837 0.9395594042885053 1.0779516022755942 1.00367317579457 1.0 16.51749250676385 -4.225008377758965 1.0327688357980054 0.997298384102007 2.1909902808379513 0.9012342037533841 0.039196738035676505 1.5071410613826552 0.5862124544152173 0.013350313421734582 2.618519677743026 5.956506530175288e-05 4.225008377758965 1.1936918967359444 IEHYFS(ph)PVSK ddPTM_PC-9_Lapatinib_30min_R1 2 IEHYFSPVSK 10 0 E9PNQ0;E9PR18;Q96PZ2 E9PNQ0 FAM111A Protein FAM111A 1 IEHY(0.404)FS(0.588)PVS(0.008)K;IEHY(0.001)FS(0.997)PVS(0.001)K 79.089 0.011054000000000001 7203700.0 110683.0 96072.0 114588.0 98109.0 92189.0 88195.0 77711.0 73884.0 88001.0 52360.0 True False 109104.64012322387 95849.55118664588 105167.01696247146 105324.26314202957 86766.62427054747 84423.10544258654 81734.49533715664 77316.92036680272 78089.40068838792 61410.35623468551 1.7766488718331175 1.5608043506594835 1.7125290164506735 1.7150895972582032 1.4128988918247043 1.3747372693940356 1.3309562156715147 1.2590208737973896 1.2715998648495355 1.0 15.906194351570596 -7.058293260167033 0.3409810040252519 0.999755538095132 1.8298204419825097 0.8910520123199437 0.07737008228976994 0.5477669324468225 0.14936441302742345 0.10317569237399714 0.1652457679522653 8.743931361943255e-08 7.058293260167033 0.8300649038873777 IELLGSYDPQK ddPTM_PC-9_Lapatinib_30min_R1 1 IELLGSYDPQK 11 0 P24666-3;P24666-2;P24666 P24666-3 ACP1 Low molecular weight phosphotyrosine protein phosphatase 0 111.06 0.0050787 0.0 26910.0 27593.0 27327.0 23936.0 25444.0 24584.0 26353.0 26581.0 24950.0 25816.0 False True 26526.258465310402 27529.11010380886 25080.279545270518 25696.33328815528 23947.4339448287 23532.599628103024 27717.429393780683 27816.050298711307 22139.868264852434 30278.26120234228 0.8760826220515718 0.9092037987200946 0.8283262825981019 0.8486726868637837 0.7909117959183257 0.7772110647583217 0.9154234190844652 0.9186805712792879 0.7312133321295123 1.0 14.885994737224935 -10.473336374912662 7.837192748319917 1.000000000914305 0.8463413629244934 0.3760093885516067 0.06023072020617835 9.682472127984633e-10 1.1251564890017134e-10 0.05917705564374575 0.014352544178365735 3.3625103135442465e-11 10.473336374912662 -0.15365863798981172 IENHEGVR ddPTM_PC-9_AZD4547_30min_R2 5 IENHEGVR 8 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ;;;; 149.57 0.0005953999999999999 287762900.0 333417.0 273767.5 398158.0 550225.0 468336.0 400449.0 332262.0 387111.0 357807.0 394181.0 False True 439436.6704955772 362257.49055974896 392878.1647681839 423379.12714150845 403315.6304678095 375408.8607258297 361832.6743232168 327291.88987582544 376719.94754253165 380380.84316935885 1.1552544729491665 0.9523547178175302 1.032854760756868 1.1130400879652218 1.0602942753566569 0.9869289357421309 0.9512378996492108 0.860432105751718 0.9903757097851607 1.0 18.53708506511348 -6.959158527056624 2.7811982610813204 0.939793615838748 1.057858630403779 0.43028552480981075 0.06082120861584625 0.2576689520705196 4.050446191129162 0.024095277607334688 0.019908780724909442 1.0986047512893364e-07 6.959158527056624 0.11806501456503093 IENHEGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 9 IENHEGVR 8 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ;;;;;;;; 143.73 0.0014398 278722790.0 348834.50000000006 395692.1 414469.3 454166.0 469202.5 435069.6 408449.1 394705.3 388060.3 325258.89999999997 False True 407885.29105457076 434973.7966500128 424351.819995573 428720.55144603836 377265.6383233278 412253.78427974146 369757.8443325966 384344.7040998337 393734.9477495403 384225.76382196357 1.0615771493229957 1.1320786829161307 1.1044335386947202 1.1158037586586518 0.9818853232812862 1.0729467492730786 0.9623452645511015 1.000309558309383 1.024748949245327 1.0 18.55159473496024 -6.255676824316229 24.986901343438817 1.0081154546091424 1.105585119618854 0.6874957992836979 0.031833711029061906 266.50308439958553 1155579.029912111 0.009208959357136942 0.01156311854558239 5.550385854635418e-07 6.255676824316229 0.09746966500971155 IENHEGVR ddPTM_PC-9_Lapatinib_30min_R1 7 IENHEGVR 8 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ;;;;;; 128.12 0.0028028000000000003 293451600.0 320427.0 312591.4 334103.0 277456.6 315488.2 288798.9 287194.8 305268.6 328937.0 261165.7 False True 315857.6522208847 311867.61381885794 306634.3410148759 297861.6839320846 296931.8043496664 276447.64427011757 302064.3414890512 319452.4935938143 291888.6511998304 306307.84326357883 1.031177161040203 1.018150924560214 1.0010659137807847 0.9724259123060512 0.9693901441960652 0.9025157218459912 0.9861462843089 1.042913201928442 0.9529258150554746 1.0 18.224622783236555 -5.463665831326691 2.1189062333470106 0.9740731026972141 1.0270266155508228 0.26231928131745075 0.03352123824555327 0.48881498568393134 4.235612499585012 0.010366918111361501 0.028193181434527252 3.438224009121276e-06 5.463665831326691 0.05295351285360861 IEPEPFENCLLRPGS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 2 IEPEPFENCLLRPGSPAR 18 1 A0A2R8Y5T7;A0A2R8Y430;P48637-2;P48637 A0A2R8Y5T7 GSS Glutathione synthetase 1 IEPEPFENCLLRPGS(1)PAR;IEPEPFENCLLRPGS(1)PAR 79.347 0.0019199000000000002 64852000.0 36826.0 45675.0 52428.0 56765.0 56505.0 59075.0 50819.0 55317.0 36467.0 52452.0 True False 48535.901971615436 60438.55052669343 51732.770464153364 43678.70626050751 48660.25609729682 55381.03091124809 55341.792550552134 46769.0287082027 38394.57117114395 50615.671445146254 0.9589105623979576 1.194067939851248 1.0220702202917082 0.8629482730036182 0.9613673929038247 1.0941479057778816 1.0933726841997486 0.9240029297820878 0.7585510588899985 1.0 15.62729651576859 -7.95850661291031 6.8080109480907245 0.8666874876827454 1.0260344964177268 0.2702602661311533 0.10109919038002899 0.23049526751159854 28.105176487629507 0.05862290789536007 0.02749846908618674 1.1002550918163846e-08 7.95850661291031 0.15934700873498142 IEPEPFENCLLRPGS(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 IEPEPFENCLLRPGSPAR 18 1 A0A2R8Y5T7;A0A2R8Y430;P48637-2;P48637 A0A2R8Y5T7 GSS Glutathione synthetase 1 IEPEPFENCLLRPGS(1)PAR;IEPEPFENCLLRPGS(1)PAR;IEPEPFENCLLRPGS(1)PAR;IEPEPFENCLLRPGS(1)PAR;IEPEPFENCLLRPGS(1)PAR 83.89399999999999 0.00095014 51794100.0 68963.3 78852.5 85601.5 85548.9 96604.5 83424.5 84191.8 75254.8 75259.3 63590.0 True False 80637.42460273788 86680.45508198204 87642.5644054967 80755.87248627604 77675.54170620583 79049.57235956108 76216.54320815306 73279.44123905155 76359.82488589255 75118.36362183698 1.0734715283294125 1.1539183084225753 1.1667262195261523 1.0750483449402541 1.0340419833589862 1.0523335246959677 1.0146193225380225 0.9755196693042598 1.016526734665113 1.0 16.19687801521986 -6.279218922638177 1.3555089266734524 1.0063939379126459 1.1337211363140487 0.7513414646416068 0.02987577202892642 0.21251290080771754 0.7897954430041095 0.01217707235783405 0.016876808412971706 5.257521742177561e-07 6.279218922638177 0.12732719840140283 IEPEPFENCLLRPGS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 3 IEPEPFENCLLRPGSPAR 18 1 A0A2R8Y5T7;A0A2R8Y430;P48637-2;P48637 A0A2R8Y5T7 GSS Glutathione synthetase 1 IEPEPFENCLLRPGS(1)PAR;IEPEPFENCLLRPGS(1)PAR;IEPEPFENCLLRPGS(1)PAR 91.337 0.00058903 50387200.0 69297.0 66831.0 79194.4 70426.0 77211.0 70903.0 60105.0 53168.0 72451.0 62480.0 True False 68308.81207248666 66676.25692558424 72683.34213122442 75605.36297424894 72669.60078266647 67870.64397296579 63216.94280397633 55638.37937932669 64290.80543714718 73279.58475063313 0.9321670190263527 0.9098885747303331 0.9918634552660512 1.0317384198004167 0.9916759358006407 0.9261876169730804 0.8626815097151617 0.7592616629674062 0.8773358317453035 1.0 16.161123707767334 -7.1041009084513105 3.152098128172521 0.8547458294626434 0.9719259843723357 0.31856022840620546 0.06379987442524815 0.26567059635722223 5.019275050952626 0.026533023747092807 0.02019792498492347 7.868629406164398e-08 7.1041009084513105 0.11718015490969225 IEPGTS(ph)TPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IEPGTSTPR 9 0 Q86X27;Q86X27-3;H7C2H2;A0A0A0MR31 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 IEPGT(0.098)S(0.804)T(0.098)PR 85.355 0.025923 0.0 40146.0 47257.0 75137.0 58843.0 86723.0 60740.0 58036.0 48968.0 47693.0 39521.0 True False 46941.924880356775 51948.36264936726 76928.55103865935 55546.217481579995 69730.25069626453 57554.68747334111 52538.40993574627 47682.64188588473 48390.41989870855 46685.84445193614 1.0054851836017291 1.1127219237267727 1.647791786605865 1.1897871428408189 1.4936058566543227 1.2328081059472884 1.1253606002529406 1.021351170695323 1.0365116121767337 1.0 15.510697558290303 -7.380276651886103 2.388469871532657 1.023880427122412 1.2979318635883068 0.3219635248888666 0.1718898103105893 0.37869115859582836 4.214480107803967 0.09033843691863205 0.05434628742131366 4.166039161869858e-08 7.380276651886103 0.2740514364658948 IEPGTST(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 IEPGTSTPR 9 0 Q86X27;Q86X27-3;H7C2H2;A0A0A0MR31 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 IEPGT(0.013)S(0.08)T(0.907)PR;IEPGT(0.01)S(0.091)T(0.899)PR 101.38 0.0038241 0.0 70322.0 72261.0 101294.0 143660.0 129204.0 119633.0 102077.0 131606.0 96982.0 113848.0 True False 92682.93321153353 95617.95510912726 99950.77537567608 110541.40652487469 111266.25482338062 112152.32959805931 111161.65525064865 111269.31670502237 102108.2705273228 109862.21617263443 0.8436288329182632 0.870344313452369 0.9097829887084765 1.0061822014510702 1.0127799957042547 1.0208453233987766 1.0118278979187194 1.0128078659015658 0.9294211794059635 1.0 16.745335774164104 -5.576973149391107 2.4595820559904604 1.0023419279028025 0.8564747499506141 0.8386532102639377 0.025626310299899896 0.1064896064535931 1.2896681017468838 0.007522345503301345 0.016448432658394588 2.648663889339713e-06 5.576973149391107 -0.1458671779521884 IEPGTST(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IEPGTSTPR 9 0 Q86X27;Q86X27-3;H7C2H2;A0A0A0MR31 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 IEPGT(0.02)S(0.126)T(0.854)PR;IEPGT(0.002)S(0.02)T(0.979)PR 123.86 8.0555e-05 3940000.0 102019.0 109532.0 124778.0 148794.0 154499.0 133470.0 125130.0 100316.0 94981.0 91493.0 True False 119288.801732903 120405.61308822989 127753.18074320011 140457.55457665675 124226.03003035145 126470.59823949357 113276.78053725156 97682.81129358771 96369.917438602 108079.95664181029 1.1037088229803804 1.1140420187923306 1.1820247223690994 1.2995707894494224 1.1493900801797243 1.1701577440360384 1.048083141934116 0.9038013552995775 0.891653923936917 1.0 16.721739475450484 -7.497223752218686 2.6240112563868445 0.9229554454530681 1.1734548383793166 0.7754190150751332 0.05742481310585711 0.13455600513903693 1.8471855249577493 0.03248122651035523 0.018197576112762962 3.1825574185569956e-08 7.497223752218686 0.25049939292624857 IEPGTST(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 IEPGTSTPR 9 0 Q86X27;Q86X27-3;H7C2H2;A0A0A0MR31 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 IEPGT(0.042)S(0.435)T(0.523)PR;IEPGT(0.002)S(0.016)T(0.982)PR 105.2 0.0024181 16423000.0 143854.0 120036.0 147468.0 109918.0 101637.0 98464.0 82594.0 84985.0 99825.0 69403.0 True False 141802.6155804071 119758.0640169901 135343.75028294156 118001.73639569918 95658.91148603025 94252.92425079481 86870.31318445424 88933.71335299565 88581.65729614814 81399.21607631554 1.7420636514172392 1.4712434565059123 1.6627156477287266 1.4496667423070397 1.1751822203833706 1.157909483580632 1.0672131424829607 1.092562283027593 1.0882372283917172 1.0 16.31272728008203 -6.212066722629637 1.6563088968169026 1.0801503764167852 1.6217216352345225 0.9187875162504254 0.0724131063643414 0.09351018389188656 0.508458425443294 0.02440934014512451 0.03414544165726004 6.136677173692617e-07 6.212066722629637 0.5415712588177373 IEPIPGES(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 IEPIPGESPK 10 0 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 IEPIPGES(1)PK;IEPIPGES(1)PK;IEPIPGES(1)PK 121.68 0.00060218 46935000.0 439862.0 405265.0 293537.0 372666.0 401557.0 377944.0 402829.0 362916.0 389549.0 376850.0 True False 579728.9663020354 536258.985860983 289644.5075863313 286753.6113323046 345807.7419283642 354311.10193348775 438680.000616823 306835.6711800361 410139.7648599549 363656.59620421357 1.5941659586355614 1.4746301633419117 0.7964780801712164 0.7885285577805836 0.9509183816211428 0.9743013206187582 1.206302883532682 0.8437511498010355 1.1278216018653995 1.0 18.47221721937342 -5.177476296320596 5.497205151126054 0.9588041405244918 1.5566011594568565 0.762204378274293 0.12842159693944707 0.10368361538504833 5.144785835114856 0.03409488071477994 0.09438254947785085 6.64543942552812e-06 5.177476296320596 0.5977970189323647 IEPIPGES(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IEPIPGESPK 10 0 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 IEPIPGES(1)PK;IEPIPGES(1)PK;IEPIPGES(1)PK;IEPIPGES(1)PK 132.17 0.00015537 34114000.0 301629.0 328210.0 194875.0 297874.0 265853.0 221778.0 319855.0 269890.0 224051.0 228287.0 True False 352688.83225569426 360792.5197356756 199521.55906755288 281185.08550053753 213761.01309172894 210147.57126214396 289556.01885033667 262805.673472092 227327.32201215203 269673.62598110177 1.307835836643551 1.337885818174 0.7398630783476579 1.0426866345478014 0.7926656242858132 0.7792663094049498 1.0737276135065141 0.9745323537516011 0.8429720228854812 1.0 18.040854907664624 -5.248054389692077 24.924216386090567 0.9071435530542773 1.3228609140275605 0.6965310080863711 0.11013437384077004 401.871332592873 748322.2204342163 0.027765562947182083 0.07255277383102128 5.648662282902948e-06 5.248054389692077 0.41571736097328316 IEPIPGES(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 IEPIPGESPK 10 0 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 IEPIPGES(1)PK;IEPIPGES(1)PK;IEPIPGES(1)PK;IEPIPGES(1)PK 102.62 0.0031456 59983000.0 411258.0 401473.0 308769.0 372490.0 363369.0 323058.0 371637.0 333065.0 297303.0 299035.0 True False 405393.38550451974 400543.4139349282 283383.2047028079 399884.1571902137 341996.3498309404 309241.56242497975 390878.54542619304 348540.4158135609 263817.6054006183 350722.80131090846 1.1558797545790214 1.1420512508391343 0.807997665517032 1.1401715420142435 0.975118665090063 0.8817264268793392 1.114494250060712 0.9937774633152153 0.7522111605362933 1.0 18.419971701060753 -5.12050703013649 10.265509840317595 0.9679675218350149 1.1523518975061666 0.30286530172829207 0.11509266813787263 0.4693394644508513 37.05566956901072 0.028532996452565382 0.07574349408121551 7.576924676292552e-06 5.12050703013649 0.18438437567115173 IEPPDRR ddPTM_PC-9_AZD4547_30min_R2 2 IEPPDRR 7 1 Q15428 Q15428 SF3A2 Splicing factor 3A subunit 2 0 ; 102.77 0.006814699999999999 5890100.0 14860.3 16159.9 26001.0 35248.0 25619.0 24882.0 22315.4 27332.0 23132.0 24316.0 False True 19585.56628655831 21383.27165093187 25656.209751248414 27122.11817617137 22062.24406612948 23326.124606579357 24301.427369342004 23108.467426877727 24354.710295086046 23464.704241214364 0.8346820008989256 0.911295170444698 1.0933958292210135 1.155868742148174 0.9402310738431747 0.9940941239569685 1.0356587971246611 0.9848181843387173 1.0379295662422388 1.0 14.518204655708406 -5.055165666506887 4.452847871643454 1.0294591200577254 0.8479644045059408 0.5632216399388266 0.057139410614690064 0.14677836215989037 6.009152100398501 0.01568174751016328 0.05054245022958538 8.807128511156981e-06 5.055165666506887 -0.18149471555178465 IEPPDRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IEPPDRR 7 1 Q15428 Q15428 SF3A2 Splicing factor 3A subunit 2 0 120.62 0.00046012 0.0 8419.4 6824.4 9235.4 7751.6 9921.0 10737.0 10679.0 8494.3 8291.7 6992.0 False True 9844.638129270063 7501.881331111615 9455.606961449543 7317.302983026275 7977.051268494403 10173.932818591751 9667.407810735307 8271.33362545479 8412.950426144753 8259.59425135846 1.1919033586487509 0.9082626946084884 1.1448028406352255 0.8859155498858547 0.9657921473784761 1.2317715022040507 1.1704458495821757 1.001421301548124 1.0185670349074436 1.0 13.011855196339397 -5.370024093786861 16.16416434936104 1.0539402533457403 1.044308003865529 0.0 0.11690747694161599 42.663801396084814 6206.564412168088 0.031584049350240194 0.06574878632627675 4.265558536818648e-06 5.370024093786861 -0.009632249480211241 IEPPDRR ddPTM_PC-9_Lapatinib_30min_R1 2 IEPPDRR 7 1 Q15428 Q15428 SF3A2 Splicing factor 3A subunit 2 0 ; 120.62 0.0037813 5750700.0 25244.0 26993.0 24586.0 26418.0 24715.0 28131.0 21528.0 21468.4 26866.0 22748.0 False True 24884.01593081737 26930.499366944965 22564.633984704527 28360.86784786456 23261.312291559538 26927.902706563895 22642.614502687 22465.900238247385 23840.068168477974 26679.961490195314 0.9326856015126581 1.0093904886947354 0.8457521197321392 1.06300257810668 0.8718645377396027 1.0092931624530155 0.8486749319712471 0.8420514492310431 0.8935570681853878 1.0 14.703468963690225 -7.2721380824757995 24.940831823056893 0.8829084847591088 0.9539079642415125 0.12595952182608916 0.07320636409588009 1202.6345131231124 2803571.1731649046 0.028212776617782896 0.01925452950321922 5.343944234662006e-08 7.2721380824757995 0.0709994794824037 IEPSELPLPGGGNRS(ph)SSVPHPFQVTLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IEPSELPLPGGGNRSSSVPHPFQVTLLR 28 1 Q5VV41;Q5VV41-2 Q5VV41 ARHGEF16 Rho guanine nucleotide exchange factor 16 1 IEPSELPLPGGGNRS(0.455)S(0.455)S(0.089)VPHPFQVTLLR 62.605 0.00034995 1347600.0 3834.7 1617.7 3185.5 4148.8 5667.7 6841.9 4649.9 6613.0 5325.4 3762.1 True False 4483.838971222637 1778.294564993151 3261.4544010760237 3916.3561865910797 4557.1548709248755 6483.098719523415 4209.427809639302 6439.415757052681 5403.273900333016 4444.138949232784 1.0089331189783584 0.40014378157553954 0.7338776843687721 0.881240715317234 1.0254303303706562 1.458797484413179 0.9471863633710188 1.4489681422234453 1.2158201987059412 1.0 12.117688209002786 -6.21008740606492 1.9182968811141492 1.2251566531329519 0.6872964717888816 0.5169094035366948 0.2091462062441516 0.24507664860900286 1.7741469212553633 0.06819698219101573 0.09284172308624387 6.164709184986801e-07 6.21008740606492 -0.5378601813440702 IEQHYFEDR ddPTM_PC-9_Lapatinib_30min_R1 1 IEQHYFEDR 9 0 O75431-2;O75431;C9JNK6 O75431-2 MTX2 Metaxin-2 0 65.627 0.044696 0.0 18675.0 13083.0 18085.0 17247.0 13959.0 15096.0 13205.0 16323.0 16454.0 13433.0 False True 18408.691075424424 13052.707117317123 16598.121110118816 18515.4019143054 13137.959064449922 14450.379270494775 13888.690287438774 17081.426170041184 14600.777251698666 15754.876151652612 1.1684440358798656 0.8284868120621789 1.0535227919502086 1.175217230277194 0.8338979588279285 0.9172004356872713 0.8815486807861651 1.084199330138779 0.9267465584086558 1.0 13.943510792990978 -4.729695162214558 24.569434901905797 0.9702514457854433 1.1684456849618794 0.242396523757619 0.10680774773596988 5591.061760065156 4327074.6863049315 0.026927886143220166 3.9065992193636894 1.8633946222628367e-05 4.729695162214558 0.19819423917643608 IERPGEGS(ph)PMVDNPMR ddPTM_PC-9_Lapatinib_30min_R1 2 IERPGEGSPMVDNPMR 16 1 A0A087WTW0;A0A087WVR3;Q96T88;Q96T88-2 A0A087WTW0 UHRF1 E3 ubiquitin-protein ligase UHRF1 1 IERPGEGS(1)PMVDNPMR;IERPGEGS(1)PMVDNPMR 97.384 0.0010359000000000002 14945200.0 44039.0 44675.0 47067.0 40430.0 47243.0 43373.0 41211.0 39362.0 45743.0 32015.0 True False 43410.9957842365 44571.55778232384 43197.332943874055 43403.35707052632 44464.25962331167 41518.037897401286 43344.703933028366 41190.902218045754 40590.94164485549 37548.75009269397 1.1561235907206182 1.1870317300121351 1.1504333123535624 1.1559201561537866 1.184174160619085 1.1057102512043309 1.1543581031599277 1.096997959089468 1.08101978214059 1.0 15.196477264250799 -8.46198959870961 0.5262758462221542 0.995690186456263 1.1695574458082505 0.8651705024195908 0.019927053057019493 0.3078915901894568 0.20994376516976004 0.021170406636740028 0.010152764939849256 3.451520055777683e-09 8.46198959870961 0.17386725935198755 IES(ph)DEEEDFENVGK ddPTM_PC-9_AZD4547_30min_R2 7 IESDEEEDFENVGK 14 0 Q96T23-3;Q96T23-2;Q96T23 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 IES(1)DEEEDFENVGK;IES(1)DEEEDFENVGK;IES(1)DEEEDFENVGK;IES(1)DEEEDFENVGK;IES(1)DEEEDFENVGK;IES(1)DEEEDFENVGK;IES(1)DEEEDFENVGK 238.64 3.1275999999999993e-37 65047700.0 168965.9 178065.69999999998 190359.3 222139.80000000002 219212.1 227715.59999999998 199064.59999999998 221532.40000000002 204053.8 208735.69999999998 True False 222693.54149095167 235621.95526044947 187835.01130344288 170928.9011356977 188778.2837912789 213476.50753404028 216780.96376077167 187299.65788811859 214839.6672839111 201427.92667720251 1.105574312184766 1.1697581320888262 0.9325172254017046 0.8485859133605594 0.9372001534514365 1.0598158411080016 1.0762209954539874 0.9298594339814403 1.0665833225211196 1.0 17.619904191970328 -5.258347827025447 24.99953904473768 0.9787153914924525 1.137666233248757 0.4409554603479494 0.070353815315234 255.63459834866393 2067141.6841251971 0.01972869955974142 0.04778993642498619 5.5163545674465815e-06 5.258347827025447 0.15895084175630458 IES(ph)DEEEDFENVGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 IESDEEEDFENVGK 14 0 Q96T23-3;Q96T23-2;Q96T23 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 IES(1)DEEEDFENVGK;IES(1)DEEEDFENVGK;IES(1)DEEEDFENVGK;IES(1)DEEEDFENVGK;IES(1)DEEEDFENVGK 229.23 1.0748e-47 58460000.0 185512.0 206372.40000000002 170003.8 238936.7 219513.7 202859.7 227713.7 194255.4 184149.2 161332.8 True False 216915.51757098493 226859.6880043228 174057.33533500173 225549.8513422337 176501.56627728 192221.3802179079 206143.0098315797 189156.40158060926 186842.0336739404 190581.1595302583 1.1381792308622487 1.19035737091475 0.9132977035296445 1.1834845159834568 0.9261228481992582 1.008606415721745 1.0816547151863176 0.9925241406172532 0.9803804013705549 1.0 17.54004597880664 -5.241448146897905 24.902623692677768 1.0160930275878308 1.1642683303600578 0.4075157808527513 0.07381528685903266 750.7569137002458 935197.118748795 0.017733151217591097 0.04677650037587829 5.73524339073375e-06 5.241448146897905 0.148175302772227 IES(ph)DEEEDFENVGK ddPTM_PC-9_Lapatinib_30min_R1 7 IESDEEEDFENVGK 14 0 Q96T23-3;Q96T23-2;Q96T23 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 IES(1)DEEEDFENVGK;IES(1)DEEEDFENVGK;IES(1)DEEEDFENVGK;IES(1)DEEEDFENVGK;IES(1)DEEEDFENVGK;IES(1)DEEEDFENVGK;IES(1)DEEEDFENVGK 230.23 2.0881999999999997e-27 53847900.0 172751.0 154527.09999999998 156421.0 166477.6 170353.9 160655.1 159813.09999999998 146497.59999999998 157249.8 140511.3 True False 170287.53906134664 154169.30199406677 143560.66918252097 178720.91805699375 160334.0185306536 153784.25587832963 168087.44034649612 153304.41331178223 139538.67161019618 164798.4909854612 1.0333076355436392 0.9355019033983015 0.8711285420397821 1.0844815203602853 0.9729095064638579 0.9331654371270713 1.0199573997393283 0.9302537444065978 0.8467229934921341 1.0 17.330343506656007 -7.983416674155079 23.079355810434397 0.9117371267844477 0.9749555298199155 0.11326738289198712 0.0659776337463374 174.64603223587787 243057.8120102028 0.03543281525387668 0.017010558455950082 1.0389229160891362e-08 7.983416674155079 0.06321840303546777 IES(ph)DVQEPTEPEDDLDIMLGNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IESDVQEPTEPEDDLDIMLGNK 22 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 IES(0.999)DVQEPT(0.001)EPEDDLDIMLGNK 119.45 7.223100000000001e-07 2821900.0 32453.0 34832.0 24566.0 27174.0 24902.0 24300.0 27979.0 18832.0 21113.0 18071.0 True False 37946.651924032725 38289.890763331576 25151.74660707381 25651.528879296664 20022.63186050272 23025.665222294836 25328.626569581724 18337.679954153347 21421.737683128194 21347.129250042715 1.7775997643316277 1.7936786869482677 1.1782261826621714 1.2016383364168433 0.9379543087960014 1.0786305246289152 1.1865120725556595 0.8590232316186802 1.0034950101351605 1.0 14.381754449620242 -5.335952029125205 2.080149841265214 1.0317573278738952 1.8392555018844539 0.8925115603301862 0.10184530558710625 0.10194754721023552 0.8204374975239669 0.029202906730251176 0.09797581886039329 4.613685331398074e-06 5.335952029125205 0.8074981740105587 IES(ph)DVQEPTEPEDDLDIMLGNKK ddPTM_PC-9_AZD4547_30min_R2 1 IESDVQEPTEPEDDLDIMLGNKK 23 1 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 IES(1)DVQEPTEPEDDLDIMLGNKK 89.08 8.819500000000001e-06 4274500.0 16754.0 12521.0 15343.0 20323.0 17167.0 17750.0 14126.0 16240.0 10927.0 13163.0 True False 22081.423495151394 16568.168388499787 15139.541795061883 15637.846337220006 14783.658373989818 16640.08969402714 15383.186634311964 13730.481158074575 11504.578912087367 12702.167376505387 1.7383980891319684 1.304357586969383 1.1918864982888506 1.2311163814566488 1.1638689631294317 1.310019715596375 1.2110678578181495 1.080955773222703 0.9057177858769878 1.0 13.63278706525176 -1.522878745284008 0.8054486906977409 1.1300680255825306 155.06734286709403 0.7428147648057112 0.10808213482650336 283.8032687150328 0.9624353688060646 0.040868647577884956 79757.7128989178 0.029999999999746455 1.522878745284008 153.9372748415115 IES(ph)DVQEPTEPEDDLDIMLGNKK ddPTM_PC-9_Lapatinib_30min_R1 2 IESDVQEPTEPEDDLDIMLGNKK 23 1 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 IES(0.987)DVQEPT(0.013)EPEDDLDIMLGNKK;IES(0.999)DVQEPT(0.001)EPEDDLDIMLGNKK 67.899 0.004122 3082800.0 60474.0 50791.0 50087.4 46795.1 51393.8 52721.9 43978.5 50911.9 54432.0 37664.6 True False 59611.62967042665 50673.39656008975 45969.407314955264 50236.567757877456 48370.91772809846 50467.10723775157 46255.491541546864 53277.452737028674 48301.29496562913 44174.87592507516 1.3494464539421391 1.1471089731193973 1.0406233487316139 1.1372203476719098 1.0949870648225517 1.1424391394635411 1.0470995237202392 1.2060577788015152 1.0934109933336944 1.0 15.430938462203418 -4.780755400605036 3.7245624832181825 1.1034371520743675 1.375578827016301 0.6466815948663263 0.05594788463025786 0.15368153128183945 3.7258954549897965 0.01315208776783937 0.11605929532596959 1.6567027738547935e-05 4.780755400605036 0.2721416749419334 IES(ph)LSSQLSNLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IESLSSQLSNLQK 13 0 P20700;E9PBF6;A0A0D9SFE5 P20700 LMNB1 Lamin-B1 1 IES(0.984)LS(0.016)SQLSNLQK 111.12 0.00060144 2308800.0 6666.3 8930.5 7784.2 9048.7 9557.5 9256.5 9478.2 9500.1 6658.9 5809.9 True False 7794.772924573368 9817.061020381618 7969.8048497428945 8541.73067528122 7684.776484087816 8771.072844863049 8580.356279774453 9250.732441187987 6756.273815098872 6863.188878856901 1.1357363263870464 1.430393537707314 1.1612393291834198 1.244571703628225 1.1197093100208768 1.277987973183089 1.2501996420654466 1.347876709278143 0.9844219552098591 1.0 12.744663343677045 -8.27512061957307 24.617986221383465 0.9922108806162404 1.2462415019072073 0.5603392943401051 0.08990911498380463 513.5984486392032 924156.1792981194 0.0811742798799513 0.021439127689410545 5.307370185416073e-09 8.27512061957307 0.2540306212909669 IES(ph)PKLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IESPKLER 8 1 Q92598-2;Q92598-3;Q92598;A0A0A0MSM0;Q92598-4;Q5TBM3 Q92598-2 HSPH1 Heat shock protein 105 kDa 1 IES(1)PKLER 96.756 0.029067000000000003 7767700.0 28471.0 20645.0 26958.0 38889.0 35602.0 32042.0 43807.0 39954.0 31381.0 28091.0 True False 33290.577972117724 22694.499161948224 27600.780958784322 36710.17540983914 28626.043671095424 30361.66111328278 39657.28382478527 38905.24983476226 31839.887757980694 33183.67593176637 1.0032215249621885 0.6839055205521408 0.8317577900512945 1.1062721166070963 0.8626543885601302 0.9149577393328475 1.1950841102212486 1.172421340985876 0.9595045414332991 1.0 15.018186089676398 -6.465233591489875 0.8557591384039457 1.0825733086958145 0.8412248924285545 0.26832224697393325 0.12908788253700304 0.758586054400685 1.2211239901327806 0.07531069435555954 0.09814171569463058 3.425834735690241e-07 6.465233591489875 -0.24134841626726 IES(ph)PKLER ddPTM_PC-9_Lapatinib_30min_R1 1 IESPKLER 8 1 Q92598-2;Q92598-3;Q92598;A0A0A0MSM0;Q92598-4;Q5TBM3 Q92598-2 HSPH1 Heat shock protein 105 kDa 1 IES(1)PKLER 66.92 0.022522999999999998 1568700000.0 1409600.0 970460.0 956880.0 1106400.0 983540.0 896200.0 911660.0 860500.0 996020.0 715030.0 True False 1389498.8455110204 968212.9594948865 878209.0200636154 1187768.3468422017 925690.1109140385 857871.6151442374 958861.2940133598 900481.9714096921 883837.7390444226 838621.982782412 1.6568834040110518 1.15452847572933 1.047204864759042 1.4163334270124646 1.1038228545390005 1.0229538847741126 1.14337724707861 1.0737638529603513 1.053916731483704 1.0 19.677661122455007 -4.7627744792491296 5.075717931003817 1.1182471572650183 1.6894192980029823 0.6832811270425656 0.11132863624519439 0.10021371217827092 6.993295921367629 0.0282088674002636 0.20397176176550402 1.7267343190603356e-05 4.7627744792491296 0.571172140737964 IESDVQEPT(ph)EPEDDLDIMLGNK ddPTM_PC-9_AZD4547_30min_R2 6 IESDVQEPTEPEDDLDIMLGNK 22 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 IESDVQEPT(1)EPEDDLDIMLGNK;IESDVQEPT(1)EPEDDLDIMLGNK;IESDVQEPT(1)EPEDDLDIMLGNK;IES(0.004)DVQEPT(0.996)EPEDDLDIMLGNK;IES(0.005)DVQEPT(0.995)EPEDDLDIMLGNK;IES(0.004)DVQEPT(0.996)EPEDDLDIMLGNK 118.09 1.2217e-06 23584900.0 168991.0 155476.0 174865.0 199256.0 185244.0 191675.0 126408.0 164307.0 135157.0 146693.0 True False 222726.62276883866 205730.57650110955 172546.1758452385 153320.607674512 159526.0681441936 179689.531949445 137658.06711525575 138917.1285492464 142301.12309151576 141557.32271987436 1.5734023396980248 1.453337577655567 1.218913811945197 1.0830990917927703 1.1269361773666582 1.2693764511570333 0.9724545821459566 0.9813489396387315 1.0052544111272386 1.0 17.111026855813257 -1.5228787456838186 0.36699412208153653 0.9943155951088443 9.132397892979563 0.8492509487286872 0.07719697546119099 25.010729651871564 0.3466677198227504 0.06696701596562822 143.09573129612122 0.029999999972128513 1.5228787456838186 8.138082297870719 IESDVQEPT(ph)EPEDDLDIMLGNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 IESDVQEPTEPEDDLDIMLGNK 22 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 IES(0.04)DVQEPT(0.96)EPEDDLDIMLGNK;IESDVQEPT(1)EPEDDLDIMLGNK;IES(0.013)DVQEPT(0.987)EPEDDLDIMLGNK;IES(0.013)DVQEPT(0.987)EPEDDLDIMLGNK;IES(0.022)DVQEPT(0.978)EPEDDLDIMLGNK;IES(0.012)DVQEPT(0.988)EPEDDLDIMLGNK 100.7 9.0323e-05 14570200.0 144979.0 139781.0 131309.0 134752.0 136299.0 111406.0 130423.0 102911.0 116016.0 92973.0 True False 169521.0812342261 153657.53389955344 134439.90455215576 127202.28231187872 109592.18938055799 105563.67324094565 118068.38925924987 100209.69529321743 117712.51451929174 109828.26892613717 1.5435104540183013 1.3990708895074435 1.2240919925868143 1.1581925451035389 0.9978504664792819 0.9611703277590617 1.0750273168618767 0.9124216950065149 1.0717870332496724 1.0 16.74488991484943 -5.26020529934293 0.8842587618350678 0.9932618342224531 1.651860281524314 0.9311045497784024 0.05045276752490082 0.2758555267937161 0.27161324572701684 0.018574824848679387 0.15297683410154195 5.49281156723198e-06 5.26020529934293 0.6585984473018609 IESDVQEPT(ph)EPEDDLDIMLGNK ddPTM_PC-9_Lapatinib_30min_R1 6 IESDVQEPTEPEDDLDIMLGNK 22 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 IES(0.001)DVQEPT(0.999)EPEDDLDIMLGNK;IES(0.001)DVQEPT(0.999)EPEDDLDIMLGNK;IES(0.018)DVQEPT(0.982)EPEDDLDIMLGNK;IES(0.042)DVQEPT(0.958)EPEDDLDIMLGNK;IES(0.002)DVQEPT(0.998)EPEDDLDIMLGNK;IES(0.002)DVQEPT(0.998)EPEDDLDIMLGNK 93.949 0.00038803 13789300.0 130928.1 123583.0 124812.0 110437.5 135264.0 133765.1 115646.5 114065.9 141145.4 96218.1 True False 129061.04128472718 123296.85115641679 114550.43914825255 118559.44215870013 127308.037459256 128044.27849467797 121634.1099073298 119365.81813204057 125248.1187250463 112849.27038244093 1.1436586239977036 1.092579958546205 1.0150746988442765 1.0505999884350843 1.128124595115369 1.1346487049561054 1.0778457804389647 1.0577455904456925 1.1098708773267763 1.0 16.78403756537208 -10.724475651459036 3.5441122517792256 0.9998707700445383 1.0878548756670618 0.32405518951394274 0.03888963061588144 30048695.281910304 44576255.56096324 42500.45067039383 0.010437815624728092 1.8859247001167977e-11 10.724475651459036 0.08798410562252357 IESDVQEPT(ph)EPEDDLDIMLGNKK ddPTM_PC-9_AZD4547_30min_R2 1 IESDVQEPTEPEDDLDIMLGNKK 23 1 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 IES(0.003)DVQEPT(0.997)EPEDDLDIMLGNKK 60.621 0.0022982 2723400.0 21177.0 18824.0 26058.0 34247.0 28393.0 25112.0 19084.0 26783.0 18573.0 23122.0 True False 27910.84549103623 24908.489876616906 25712.453894005273 26351.883260875537 24451.12204885494 23541.742670220276 20782.439029393267 22644.302762112773 19554.730862468994 22312.505817789064 1.2509059143318535 1.1163465941489255 1.1523785855332096 1.1810364768562214 1.0958483214987367 1.0550918333632961 0.9314255959912883 1.0148704474088777 0.8764022751258452 1.0 14.445564924861241 -6.83104680442209 1.3806831890528475 0.9518610770044523 1.1719487781295799 0.7978361546904685 0.04913839326838182 0.17540180351548962 0.6963643310197597 0.022502231972255687 0.01912359247494297 1.4755475032337912e-07 6.83104680442209 0.22008770112512754 IESDVQEPT(ph)EPEDDLDIMLGNKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IESDVQEPTEPEDDLDIMLGNKK 23 1 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 IES(0.003)DVQEPT(0.997)EPEDDLDIMLGNKK 46.568999999999996 0.023842 6306500.0 24618.0 14856.0 19520.0 20342.0 21661.0 23142.0 21777.0 21685.0 21162.0 13038.0 True False 28785.34117233655 16330.805500116388 19985.43083001224 19202.303689653814 17416.682544789546 21928.392780837326 19714.124908173308 21115.791727156724 21471.454215429316 15401.686191248784 1.8689733588191362 1.060325817402742 1.2976131692235058 1.2467663248823064 1.1308295941444177 1.4237657168535875 1.279997830326841 1.3710051915714714 1.394097629883497 1.0 13.910800686741236 -4.749495404716288 24.99961672509109 1.261349433171557 1.8689747281569007 0.6546027428256163 0.1355177437720475 340.7519761533032 713175.0247564322 0.03259229609067912 0.5294558428492814 1.7803467466595624e-05 4.749495404716288 0.6076252949853438 IESDVQEPT(ph)EPEDDLDIMLGNKK ddPTM_PC-9_Lapatinib_30min_R1 2 IESDVQEPTEPEDDLDIMLGNKK 23 1 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 IESDVQEPT(1)EPEDDLDIMLGNKK;IESDVQEPT(1)EPEDDLDIMLGNKK 84.291 1.6892e-05 6208700.0 50564.0 32621.0 34796.0 28066.0 33075.0 39162.0 24908.1 25247.2 36572.0 23052.0 True False 49842.948087698045 32545.468078728267 31935.20719644425 30130.067265431408 31129.593527951914 37487.13255108082 26197.719541730676 26420.27708143499 32452.87623976686 27036.507485140766 1.8435424070616988 1.2037600676276408 1.1811883326274966 1.11442157541949 1.151391079083003 1.386537538980717 0.9689757286930981 0.9772074701569922 1.2003353708907456 1.0 14.722621179124676 -4.742127439979558 3.438362101565896 1.1286055249430231 1.9711620373187264 0.7667607938314768 0.11848799228205077 0.17756723315919906 3.149693663843687 0.03093176150503878 0.41591115185339755 1.8108086484297307e-05 4.742127439979558 0.8425565123757033 IESFGS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 IESFGSPK 8 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 IES(0.002)FGS(0.998)PK;IES(0.001)FGS(0.999)PK 93.561 0.0071324 21475000.0 139915.0 124446.0 138975.0 176799.0 174225.0 150351.0 133291.0 139899.0 130886.0 136837.0 True False 184405.05958720922 164670.73582583215 137132.10069534802 136040.72206732086 150036.86609240863 140949.52820206623 145153.64078111813 118280.82410920392 137804.36675093503 132046.37827994104 1.3965173599556566 1.2470674165460776 1.0385146679648052 1.030249552009005 1.1362437050286027 1.0674244158612993 1.0992625672276253 0.8957521262601095 1.043605803854665 1.0 17.01068520676936 -5.035702994536133 2.278981468367606 1.0398292573908745 1.4098097865270816 0.789058348783474 0.06080335034792413 0.17418948251498664 1.5220041604034948 0.017394539208727147 0.10434846040960521 9.210792644244889e-06 5.035702994536133 0.36998052913620705 IESFGS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IESFGSPK 8 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 IES(0.034)FGS(0.966)PK 87.789 0.030079 0.0 66351.0 61119.0 47468.0 67178.0 60438.0 55227.0 71624.0 53593.0 55574.0 57525.0 True False 77582.91380801436 67186.49039860074 48599.817143392465 63414.23445401463 48595.60775781317 52330.79889842289 64839.256207145394 52186.24053647728 56386.66461432135 67953.82713235049 1.1417004322200979 0.9887079688351439 0.7151888156164755 0.933195923321665 0.7151268708260652 0.7700934753314282 0.9541663647709056 0.7679661726018253 0.8297790866804261 1.0 16.05226718483761 -4.996260402132042 3.9315478877452548 0.8285624685555169 1.125634380662822 0.5116797728259714 0.09492065973223804 0.15129596715813004 5.286569569517861 0.022917518102582777 0.0949948507858267 1.0086479213826068e-05 4.996260402132042 0.2970719121073051 IESFGS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 IESFGSPK 8 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 IES(0.004)FGS(0.996)PK 75.652 0.026068 10502000.0 99875.0 95855.0 74322.0 81858.0 97694.0 74921.0 81905.0 90439.0 84748.0 63961.0 True False 98450.76418516802 95633.05363681362 68211.53205121668 87878.11039028292 91947.83099379406 71716.80347938117 86145.64013575709 94641.12610380148 75202.78780399665 75016.57362732467 1.3123868423298326 1.2748256686836925 0.9092861584172746 1.1714492696887646 1.2257002226012388 0.9560127850635187 1.1483547697568883 1.2616028902355598 1.0024823071445128 1.0 16.194921749137002 -5.033082196897006 24.032059735697096 1.0990631926118077 1.302996674435545 0.3539547268185751 0.11217566360601863 373.15806081415803 271076.19699166744 0.028017100141201554 0.07427213393428392 9.26654423207793e-06 5.033082196897006 0.20393348182373727 IET(ph)DEEESCDNAHGDANQPAR ddPTM_PC-9_AZD4547_30min_R2 2 IETDEEESCDNAHGDANQPAR 21 0 Q96T23-3;Q96T23-2;Q96T23 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 IET(0.998)DEEES(0.002)CDNAHGDANQPAR;IET(0.999)DEEES(0.001)CDNAHGDANQPAR 143.84 2.7262e-06 46883700.0 24933.0 35486.7 43314.7 54978.0 54939.0 33527.0 40096.2 45127.6 35607.7 41371.1 True False 32861.17536138292 46957.081794758866 42740.31877667779 42303.67150163271 47311.66816616915 31430.551389952023 43664.6841233682 38154.166349084146 37489.8503274397 39922.710381382785 0.8231198495157063 1.1761997456128737 1.0705765808077237 1.0596392654081983 1.1850815667122658 0.7872850087004383 1.093730453324392 0.9557008024905201 0.9390607493654137 1.0 15.284922049148518 -6.740632103885207 24.999962494160318 0.9610475034527849 1.0694591943758753 0.1746612330295102 0.11634878793922176 425.77392138067336 511566.77388948173 0.03669419029719058 0.03665666308146186 1.8170542596664306e-07 6.740632103885207 0.10841169092309044 IET(ph)DEEESCDNAHGDANQPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IETDEEESCDNAHGDANQPAR 21 0 Q96T23-3;Q96T23-2;Q96T23 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 IET(1)DEEESCDNAHGDANQPAR 186.69 8.8709e-15 8545000.0 8030.5 14183.0 6918.5 11127.0 18258.0 8510.6 17204.0 12212.0 14781.0 14280.0 True False 9389.905040395182 15590.99450781843 7083.4632785573585 10503.590264220731 14680.475966149654 8064.289153944952 15574.312573826224 11891.447939683543 14997.144162095288 16868.850959582203 0.5566416505127356 0.924247569984137 0.41991379825035796 0.6226618688722398 0.8702712473614297 0.47805800011316735 0.9232586505827993 0.7049352660815769 0.8890436105001148 1.0 14.04207408575526 -8.230454437021676 0.6390738686863642 1.0008212230286362 0.6516349488867113 0.3178468304033879 0.16393954336652128 0.8938803029366004 0.8420867858044954 0.15562250439174224 0.07058831832384085 5.882278234366897e-09 8.230454437021676 -0.34918627414192493 IET(ph)DEEESCDNAHGDANQPAR ddPTM_PC-9_Lapatinib_30min_R1 2 IETDEEESCDNAHGDANQPAR 21 0 Q96T23-3;Q96T23-2;Q96T23 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 IET(0.995)DEEES(0.005)CDNAHGDANQPAR;IET(1)DEEESCDNAHGDANQPAR 172.98 1.7352000000000002e-09 86667800.0 16944.1 19136.4 25675.0 17105.6 19488.5 22751.7 18869.9 17274.3 25359.0 19499.7 True False 16702.474026832624 19092.090841536923 23564.100608366098 18363.60288660881 18342.224745865195 21778.662827803102 19846.891090870206 18076.927040932565 22502.802377891505 22870.197163282992 0.7303161362179967 0.8348021971663787 1.0303409472217901 0.8029490413003827 0.8020142815083711 0.9522726311589348 0.8678058588289497 0.7904141320632866 0.9839356529037134 1.0 14.481181182783272 -14.522878745206162 0.10913753596447806 1.4344241258203745 0.788359344753637 0.2400324708812709 0.08615309551408445 290.8357709842258 2.1067634189984776 28.159962789126514 1.1410239567279084 3.0000000005123863e-15 14.522878745206162 -0.6460647810667375 IETELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IETELR 6 0 P63104;E7EX29;E7ESK7;B0AZS6;E9PD24;E7EVZ2 P63104 YWHAZ 14-3-3 protein zeta/delta 0 132.72 0.031330000000000004 5513800.0 54143.0 58962.0 65128.0 62169.0 71279.0 57186.0 55200.0 56757.0 54866.0 46535.0 False True 63308.340527005385 64815.357693717146 66680.89851931532 58685.87248461746 57312.39163058284 54187.06548980051 49971.0563866082 55267.18888901235 55668.3114537258 54971.4271291427 1.1516590314869766 1.1790735856547512 1.213010140025361 1.067570473416099 1.042585114189242 0.9857314666854198 0.9090369123801847 1.0053802816356727 1.0126772099793941 1.0 15.74639431363516 -6.118143207235855 1.7136052127825347 0.9810859852202505 1.181907019761644 0.8485062816075729 0.03553881729342535 0.1331295332499779 0.7774343968622232 0.012701251105879077 0.019050442934132432 7.618277583020893e-07 6.118143207235855 0.20082103454139344 IETIAASS(ph)TPTPIR ddPTM_PC-9_AZD4547_30min_R2 2 IETIAASSTPTPIR 14 0 Q96P47;Q96P47-2;Q96P47-4;Q96P47-5;H7C5G0;H7C4U6;Q96P47-3;Q96P47-6;E7ESL9 Q96P47;E7ESL9 AGAP3 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 1 IETIAAS(0.007)S(0.827)T(0.164)PT(0.002)PIR;IETIAAS(0.083)S(0.618)T(0.297)PT(0.003)PIR 110.15 0.00052222 8269700.0 17207.2 25816.0 29338.0 37084.0 38070.0 36918.0 33401.0 50906.0 37323.0 38201.0 True False 22678.73166800579 34160.51714060464 28948.958950891334 28534.85674208861 32784.637636033774 34609.511623892635 36373.624293689194 43039.64740350644 39295.81758358534 36863.59461747943 0.6152067345394561 0.9266735242473321 0.7852994058578527 0.7740660409866372 0.8893499935703081 0.93885341304947 0.9867085581622063 1.167537996500714 1.065978996116473 1.0 15.169909136463803 -6.928130030489184 1.1413759227364253 1.0848446037439328 0.7825991322829794 0.6918668900851203 0.08360824626659187 0.2679752739167353 0.7261606717966198 0.04631576970360259 0.03560112707655704 1.1799672931566094e-07 6.928130030489184 -0.3022454714609534 IETIAASS(ph)TPTPIR ddPTM_PC-9_Lapatinib_30min_R1 1 IETIAASSTPTPIR 14 0 Q96P47;Q96P47-2;Q96P47-4;Q96P47-5;H7C5G0;H7C4U6;Q96P47-3;Q96P47-6;E7ESL9 Q96P47;E7ESL9 AGAP3 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 1 IETIAAS(0.094)S(0.452)T(0.452)PT(0.003)PIR 90.689 0.0048331 3885400.0 25936.0 21726.0 26564.0 26731.0 15909.0 14187.0 16817.0 17351.0 25974.0 19898.0 True False 25566.147883920097 21675.69478184147 24380.010460005335 28696.88691200193 14973.263898297415 13580.255081512269 17687.701973787032 18157.190802939687 23048.534601654384 23337.342787581594 1.0955038076367678 0.9287987488179532 1.0446780801873712 1.2296552856596976 0.6416010612084371 0.5819109401237691 0.7579141350745003 0.7780316280310028 0.9876246328231982 1.0 14.510352683293252 -6.266339334169568 24.994539276587776 0.7679551945218075 1.0620989004777928 0.4856781330665936 0.1414719543948702 360.28218716554426 1837787.0426416511 0.04498029681497443 0.052639065582926484 5.41577565685132e-07 6.266339334169568 0.29414370595598527 IETIAASST(ph)PTPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IETIAASSTPTPIR 14 0 Q96P47;Q96P47-2;Q96P47-4;Q96P47-5;H7C5G0;H7C4U6;Q96P47-3;Q96P47-6;E7ESL9 Q96P47;E7ESL9 AGAP3 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 1 IETIAAS(0.061)S(0.342)T(0.592)PT(0.005)PIR 100.73 0.005788399999999999 0.0 7835.3 13270.0 14911.0 16339.0 20958.0 12808.0 11884.0 13046.0 10595.0 8839.1 True False 9161.66153577092 14587.357901625233 15266.5347902824 15423.578801752708 16851.430348261823 12136.325932804617 10758.2614872908 12703.556323379586 10749.931831229254 10441.558859722898 0.8774227736349758 1.3970479022911295 1.4620934474804606 1.4771337315587403 1.613880702551442 1.1623097753745455 1.030330971823522 1.216634076773927 1.0295332311630085 1.0 13.350049492923292 -6.9806327113722215 24.223570638480876 1.0884835221269125 1.3797601943419522 0.35734951042446517 0.18836753595901487 193.51047352421563 242031.24401668098 0.06808683064436091 0.06003757583624002 1.0456041267384764e-07 6.9806327113722215 0.2912766722150397 IETIEVMEDR ddPTM_PC-9_AZD4547_30min_R2 5 IETIEVMEDR 10 0 P51991;P51991-2 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 0 ;;;; 145.46 0.00063582 21473200.0 56754.6 58049.5 74463.7 106422.0 97283.3 80832.7 72715.5 95115.6 74819.6 78329.3 False True 74801.38223098476 76812.86565515675 73476.26268428274 81888.0521035097 83777.19302699137 75778.21849072623 79187.03863141095 80417.66955904914 78774.41130875924 75587.01504858324 0.98960624629649 1.0162177406501052 0.9720751988559964 1.0833613690245143 1.1083542983294674 1.0025295805373462 1.0476275400015969 1.0639085232742822 1.0421685690078821 1.0 16.205850797408438 -5.75679070832796 24.999999866824044 1.0527612331315512 0.9949915275033685 0.3893208071811294 0.032559888620314933 120.18667758255015 646337.5093254099 0.009011298876483389 0.01497781907048268 1.7506901637633268e-06 5.75679070832796 -0.05776970562818273 IETIEVMEDR ddPTM_PC-9_Lapatinib_30min_R1 5 IETIEVMEDR 10 0 P51991;P51991-2 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 0 ;;;; 162.64 0.0014478 35608800.0 57686.5 60398.6 69106.7 54156.7 68453.3 60597.8 56134.2 59202.0 63768.5 51268.8 False True 56863.87993159153 60258.75075257893 63425.01388557642 58139.56437945515 64427.011478365916 58006.17335437122 59040.554209249916 61952.74104752669 56586.22001792553 60130.54376861816 0.9456738018269596 1.0021321440972513 1.0547886300452456 0.9668890506491297 1.0714523342127178 0.9646706934428948 0.9818729469076063 1.0303040212960708 0.9410561832879616 1.0 15.875810384628277 -9.512201796963891 11.28972239492634 1.000001775358344 0.9984890952337767 0.0 0.04245594338331475 0.0 0.0 0.03905022703224232 0.009471071221075598 3.07466782397627e-10 9.512201796963891 -0.0015126801245671784 IETLDPALIRPGR ddPTM_PC-9_Lapatinib_30min_R1 1 IETLDPALIRPGR 13 1 P62191-2;P62191 P62191-2 PSMC1 26S protease regulatory subunit 4 0 78.548 0.019281 3141500.0 16891.0 15265.0 13694.0 14702.0 19774.0 14188.0 14859.0 17464.0 15190.0 13654.0 False True 16650.131242569973 15229.65483037881 12568.132180368655 15783.234124434279 18610.932197179787 13581.21231384338 15628.326314354617 18275.441195466472 13479.142242208756 16014.075707188613 1.03971852931205 0.9510167872843462 0.7848178321479337 0.9855850823378641 1.1621608725644692 0.8480796870310076 0.9759118540534416 1.1412111151231006 0.8417059147633514 1.0 13.967052911278222 -5.974924032432171 24.99232099779816 1.00091628743568 0.9206732635701733 0.06947124555892259 0.11338636970363336 567.8118645076115 565913.7356702116 0.03170986384603207 0.047031574430406786 1.059439027940422e-06 5.974924032432171 -0.08024302386550675 IEVDEGFCS(ph)PKPSEIK ddPTM_PC-9_AZD4547_30min_R2 1 IEVDEGFCSPKPSEIK 16 1 Q9UHV7 Q9UHV7 MED13 Mediator of RNA polymerase II transcription subunit 13 1 IEVDEGFCS(0.987)PKPS(0.013)EIK 52.784 0.037443000000000004 8458800.0 57065.0 74671.0 66222.0 47934.0 45532.0 66462.0 75533.0 69589.0 63254.0 55278.0 True False 75210.4829742638 98806.9404790087 65343.85301131387 36883.556872917565 39210.66773952957 62306.12063348908 82255.29067319007 58835.619046136235 66597.47730439968 53342.734045313715 1.4099480336042358 1.852303640737161 1.2249813246506154 0.6914448149880288 0.7350704541357178 1.1680338803136923 1.542014899410961 1.1029734433213794 1.248482637725811 1.0 15.703004150679952 -5.4366915663368625 5.929146995264692 1.0748523522233984 1.6212845736510224 0.43908307158462767 0.25004965333929624 0.22389276365813965 12.210261917989037 0.0724166857762178 0.15240021237486542 3.6585452733711127e-06 5.4366915663368625 0.546432221427624 IEVDEGFCS(ph)PKPSEIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IEVDEGFCSPKPSEIK 16 1 Q9UHV7 Q9UHV7 MED13 Mediator of RNA polymerase II transcription subunit 13 1 IEVDEGFCS(0.99)PKPS(0.01)EIK 69.258 0.01029 6054000.0 41557.0 51961.0 27812.0 35185.0 36046.0 24421.0 33349.0 21202.0 23672.0 20710.0 True False 48591.77931183644 57119.34468171423 28475.143557597363 33213.698521309096 28983.045058376098 23140.3197692865 30189.94129414851 20645.469965375905 24018.15821697584 24464.559059730196 1.986211122513987 2.334779242996263 1.1639344689628506 1.3576250624512742 1.1846951742565244 0.9458711155508437 1.2340276078730787 0.8438929929196767 0.9817531621287566 1.0 14.578405659946672 -5.27116078074182 20.659869194837896 1.0964819410154276 2.160495271287388 0.872182322327796 0.1640585575775173 18.505924726152685 39330.13909644544 0.04460326639821009 0.09552053622483432 5.355983362278014e-06 5.27116078074182 1.0640133302719605 IEVDEGFCS(ph)PKPSEIK ddPTM_PC-9_Lapatinib_30min_R1 1 IEVDEGFCSPKPSEIK 16 1 Q9UHV7 Q9UHV7 MED13 Mediator of RNA polymerase II transcription subunit 13 1 IEVDEGFCS(0.992)PKPS(0.008)EIK 58.864 0.024447 7641300.0 15853.0 51221.0 37821.0 44828.0 54692.0 49135.0 59863.0 56558.0 38346.0 41425.0 True False 15626.93331291585 51102.40092150888 34711.50337328196 48124.80066182419 51475.12408860913 47033.610589279284 62962.41322809141 59185.891155130135 34027.069678718675 48585.25605465716 0.32163941454452666 1.0518088216725665 0.7144452081148324 0.990522734050944 1.0594803499790337 0.9680634498739223 1.2959160523361308 1.218186255693446 0.7003579365814003 1.0 15.56823095173417 -4.759195001125455 24.981746588849987 1.007592422728749 0.32163852062388676 0.5680697915315956 0.17730416268932717 44.9793615373641 500540.1706501984 0.04547623142077516 0.2940529174415511 1.7410249660161513e-05 4.759195001125455 -0.6859539021048622 IEVEKPFAIAK ddPTM_PC-9_Lapatinib_30min_R1 1 IEVEKPFAIAK 11 1 P23284 P23284 PPIB Peptidyl-prolyl cis-trans isomerase B 0 107.55 0.0040018 0.0 28013.0 29087.0 28041.0 22758.0 24187.0 19633.0 19652.0 28194.0 25299.0 23191.0 False True 27613.529483044953 29019.650838599948 25735.577221390202 24431.69923846248 22764.368213471615 18793.342356758338 20669.484402025515 29503.996167257315 22449.560209719493 27199.533449934905 1.0152207034680236 1.066917228268465 0.9461771566325081 0.8982396438318669 0.8369396576368885 0.6909435557543843 0.7599205493752681 1.0847243472600052 0.8253656354452367 1.0 14.731294284876611 -5.585148933682205 2.1513417140679256 0.8583017953700268 1.0418167097057354 0.2864423137362019 0.10642197426439062 0.4071141036212739 3.7594699390597626 0.03292044125511615 0.07599961634545399 2.5992680368824037e-06 5.585148933682205 0.18351491433570855 IEVIEIMTDR ddPTM_PC-9_Lapatinib_30min_R1 3 IEVIEIMTDR 10 0 F8VZ49;Q32P51;F8VYN5;F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;A0A2R8Y4L2;H0YH80 F8VZ49;F8W6I7 HNRNPA1;HNRNPA1L2 Heterogeneous nuclear ribonucleoprotein A1-like 2;Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 0 ;; 179.1 0.00051203 20733500.0 50132.0 47826.7 59748.0 51799.0 55937.6 51938.0 47778.0 53758.0 52095.0 38478.7 False True 49417.108486917154 47715.96021461371 54835.75007394966 55608.47125639849 52647.46034555294 49716.732813391456 50251.71106045059 56255.79293322755 46227.512515330156 45129.69202535512 1.0950021209795369 1.0573074637381872 1.215070336468093 1.232192571249015 1.1665814230678582 1.1016413049187042 1.1134955459527127 1.2465361585366344 1.0243259025423495 1.0 15.461789312874746 -8.411649252509227 6.843014839596476 1.0008155100201648 1.152116798659465 0.4731873078153682 0.05986261926949869 0.21673365743209902 10.94420442257406 0.06112385673208092 0.01582132192394248 3.875705305728143e-09 8.411649252509227 0.15130128863930015 IEVLDS(ph)PASK ddPTM_PC-9_AZD4547_30min_R2 2 IEVLDSPASK 10 0 Q8N5I9 Q8N5I9 C12orf45 Uncharacterized protein C12orf45 1 IEVLDS(0.999)PAS(0.001)K;IEVLDS(0.982)PAS(0.018)K 152.4 0.00016113 50427000.0 222940.0 206360.0 290040.0 341370.0 300480.0 310090.0 367940.0 341960.0 303570.0 334850.0 True False 293830.28255992924 273061.8344102564 286193.8800912306 262672.42061392486 258763.53866234375 290700.0232800491 400685.9472057719 289117.9394590627 319616.090449562 323127.00342040736 0.9093337277591704 0.8450603989137572 0.885700907264861 0.8129076735569899 0.8008106284007377 0.899646331637072 1.2400261908301604 0.8947501644822397 0.9891345726798405 1.0 18.301741794748644 -7.016752661498989 24.97310681319528 1.029011113306414 0.8502782813010688 0.49806992016827834 0.08578944806854306 614.2851039509048 915710.1964347772 0.03173343931567083 0.025235400839488754 9.621600898120865e-08 7.016752661498989 -0.17873283200534518 IEVLDS(ph)PASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IEVLDSPASK 10 0 Q8N5I9 Q8N5I9 C12orf45 Uncharacterized protein C12orf45 1 IEVLDS(0.999)PAS(0.001)K;IEVLDS(1)PASK;IEVLDS(0.999)PAS(0.001)K 168.83 0.00015631 33031300.0 117990.0 151823.0 153321.0 159899.0 164277.0 136248.0 165301.0 157771.0 128597.0 111128.0 True False 137963.37659127405 166894.98407674805 156976.7541131306 150940.37742955264 132088.10112231184 129102.91502910394 149642.4926043969 153629.67842219202 130477.48784337801 131274.62671123623 1.0509523435534196 1.2713422864562063 1.195788996288149 1.1498061827406678 1.006196737568068 0.9834567293273713 1.1399193915330212 1.1702922512217844 0.9939277003650395 1.0 17.002228567702552 -6.089559754679483 5.290617863470145 1.0591705028016623 1.181290364265097 0.35206820109353887 0.07780942587948547 0.2641170862874086 11.88723869365364 0.023766815498912068 0.031262621465944315 8.136549021082036e-07 6.089559754679483 0.12211986146343468 IEVLDS(ph)PASK ddPTM_PC-9_Lapatinib_30min_R1 2 IEVLDSPASK 10 0 Q8N5I9 Q8N5I9 C12orf45 Uncharacterized protein C12orf45 1 IEVLDS(0.985)PAS(0.015)K;IEVLDS(0.94)PAS(0.06)K 142.12 0.00012626 20459000.0 75936.0 76542.0 79642.0 95307.0 86383.0 73424.0 59955.0 70400.0 70935.0 63307.0 True False 74853.13871504317 76364.77170172641 73094.14218701051 102316.19471483187 81302.12177551244 70283.8266797037 63059.176537931955 73671.04100783549 62945.553321335 74249.53059872489 1.0081294536335916 1.0284882757634275 0.9844391149358429 1.378004600026239 1.0949849934392537 0.9465895085525391 0.8492872080057957 0.9922088451438731 0.8477569193200527 1.0 16.180094284856356 -6.785667736479663 5.0335794326993755 0.9196238817618427 1.1048348033900042 0.3688748855300841 0.11239147420141042 0.21231821076915286 13.815368168922795 0.04146704117220191 0.03788779560903876 1.6380692716636273e-07 6.785667736479663 0.18521092162816144 IEVLPVDTGAGGYS(ph)GNSGSPK ddPTM_PC-9_Lapatinib_30min_R1 1 IEVLPVDTGAGGYSGNSGSPK 21 0 X6RAB3;Q92738;Q92738-2 X6RAB3 USP6NL USP6 N-terminal-like protein 1 IEVLPVDTGAGGYS(0.758)GNS(0.127)GS(0.115)PK 112.58 0.00065642 0.0 19711.0 20980.0 20291.0 20627.0 16151.0 18997.0 17932.0 12263.0 14726.0 11235.0 True False 19429.917525445297 20931.422099007355 18622.75230552507 22143.978389654865 15201.029934087735 18184.54259416991 18860.43121805015 12832.783748282483 13067.402808345369 13176.954780303513 1.4745377706303213 1.5884870554686104 1.4132819468548046 1.6805080353432622 1.1536072019317958 1.380026181872581 1.431319415791129 0.97388083682768 0.9916860933512576 1.0 13.685729378805263 -7.545436881493531 0.7837446242497921 0.9350771386997171 1.5105438238292928 0.6717026668504427 0.1411694673541163 0.3823930469572689 0.44090828267441967 0.1244095447553085 0.0633266779616152 2.8481517083088196e-08 7.545436881493531 0.5754666851295757 IEVLPVDTGAGGYSGNS(ph)GSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IEVLPVDTGAGGYSGNSGSPK 21 0 X6RAB3;Q92738;Q92738-2 X6RAB3 USP6NL USP6 N-terminal-like protein 1 IEVLPVDT(0.165)GAGGY(0.048)S(0.032)GNS(0.637)GS(0.118)PK 136.53 3.4181999999999996e-10 0.0 15526.0 15514.0 13379.0 16667.0 19511.0 15701.0 16749.0 18151.0 13289.0 14829.0 True False 18154.245147522037 17054.12739154587 13698.006100140052 15733.202025143059 15687.959610885424 14877.611919969191 15162.41346774095 17674.555482574204 13483.32648468198 17517.380313700593 1.0363561686974019 0.9735546689140268 0.781966587174376 0.8981481102421404 0.8955653944794272 0.8493057554007205 0.8655639825255269 1.0089725270593504 0.7697113519957364 1.0 14.096499418699727 -5.029496196836478 9.394332805022866 0.882640185494691 1.0209959624649143 0.31611279509304624 0.07393809862066947 0.37859338456195385 120.00492694125981 0.017562040446866288 0.04897947836912036 9.343375503159816e-06 5.029496196836478 0.13835577697022328 IEVLPVDTGAGGYSGNSGS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 IEVLPVDTGAGGYSGNSGSPK 21 0 X6RAB3;Q92738;Q92738-2 X6RAB3 USP6NL USP6 N-terminal-like protein 1 IEVLPVDTGAGGYSGNS(0.231)GS(0.768)PK;IEVLPVDTGAGGYSGNS(0.092)GS(0.908)PK 160.05 6.1413e-06 21027200.0 202370.0 198015.0 171654.0 207293.0 228965.0 199752.0 227103.0 209263.0 212983.0 214055.0 True False 266719.45044250827 262019.4763556252 169377.75580326878 159504.8014949245 197177.16197358776 187261.4758626091 247314.72704319342 176926.21173535494 224240.84656658754 206560.99960327073 1.2912381860795612 1.2684847423224628 0.8199890401798134 0.7721922424914469 0.9545711066091569 0.9065674363615153 1.197296331438151 0.8565325113412816 1.0855914088200262 1.0 17.65620836179405 -5.245430750364667 23.511062597912122 0.9451921469251557 1.279861675389733 0.5526920184385371 0.11898587906211562 277.9931586443588 408270.080283891 0.031140071471069914 0.0816849458062647 5.6828899982287715e-06 5.245430750364667 0.3346695284645772 IEVLPVDTGAGGYSGNSGS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IEVLPVDTGAGGYSGNSGSPK 21 0 X6RAB3;Q92738;Q92738-2 X6RAB3 USP6NL USP6 N-terminal-like protein 1 IEVLPVDTGAGGYS(0.002)GNS(0.248)GS(0.75)PK;IEVLPVDT(0.003)GAGGYS(0.007)GNS(0.114)GS(0.876)PK;IEVLPVDTGAGGYSGNS(0.031)GS(0.969)PK 130.17 1.3913e-06 18468000.0 113545.0 124073.0 106130.0 145322.0 175823.0 128768.0 146052.0 141898.0 122587.0 113028.0 True False 132765.9258840258 136390.1474701091 108660.54170026632 137180.0794802808 141371.74530596638 122015.17939689137 132216.897235089 138173.32785335838 124379.60296318111 133519.08167084455 0.9943591898821216 1.0215030373436988 0.813820319466694 1.0274192854206523 1.0588130440747074 0.9138407624588599 0.9902472034748881 1.0348582848554009 0.9315492692632925 1.0 17.026686411590624 IEVLPVDTGAGGYSGNSGS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 IEVLPVDTGAGGYSGNSGSPK 21 0 X6RAB3;Q92738;Q92738-2 X6RAB3 USP6NL USP6 N-terminal-like protein 1 IEVLPVDTGAGGYSGNS(0.028)GS(0.972)PK;IEVLPVDTGAGGYSGNS(0.003)GS(0.997)PK 205.55 1.6422e-24 22557000.0 221972.0 208643.0 123579.0 168887.0 161532.0 140520.0 122305.0 128113.0 127251.0 111690.0 True False 218806.6385753209 208159.8999524879 113418.81164873506 181307.51337051674 152031.00534413112 134510.28716811916 128637.35445703886 134065.5976795003 112918.65236756465 130995.46768242976 1.6703374738565029 1.5890618479803182 0.8658224109226015 1.3840747056230807 1.1605821791689577 1.026831611412773 0.9819985128713946 1.0234369177146907 0.8620042690431973 1.0 16.999157371198024 -1.5228787452892467 0.42853560837637905 0.9692782404309346 15.882406056194464 0.6670648068815899 0.15944877293289714 47.73716816953038 0.6017168473296849 0.10498840505027271 614.0200112689549 0.029999999999384578 1.5228787452892467 14.913127815763529 IEWLESHQDADIEDFK ddPTM_PC-9_AZD4547_30min_R2 1 IEWLESHQDADIEDFK 16 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 123.76 3.1721e-05 2288800.0 22383.0 27715.0 22605.0 29017.0 26084.0 23128.0 28279.0 30385.0 27739.0 25167.0 False True 29500.328404677886 36673.33175363563 22305.242930155397 22327.578958181035 22462.68684261376 21681.802503856903 30795.776216318 25689.696427838444 29205.226909709127 24285.91099023861 1.2147095662392544 1.5100661353974316 0.9184437404518481 0.9193634518036116 0.9249266725733422 0.8927728719985676 1.2680511029088404 1.0578024616068167 1.2025584266304759 1.0 14.567831983944817 -5.265972762212674 24.99958537359936 1.0219525947089634 1.3623878567390655 0.49782423234968864 0.1363480538080488 291.5667409788787 1607869.823171315 0.037106322422590265 0.0816698508511894 5.4203488431256004e-06 5.265972762212674 0.3404352620301021 IEWLESHQDADIEDFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IEWLESHQDADIEDFK 16 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 ; 153.48 2.5946999999999997e-05 8142600.0 37671.0 40116.0 39954.0 40466.0 42517.0 29961.0 47241.0 27152.0 26865.0 28094.0 False True 44047.956263835 44098.45136259212 40906.6548863888 38198.82121254211 34186.09906083827 28389.79241667388 42765.99048477825 26439.288769922012 27257.849801413307 33187.21980801838 1.32725659210515 1.328778114517971 1.2326026441210156 1.1510099801524465 1.0300983106930381 0.8554435285903222 1.2886282952344668 0.7966707944464213 0.8213357418637256 1.0 15.01834015517882 -5.8747175844919 0.6944284032926183 0.9270616527019889 1.3995130636027773 0.5790049135621738 0.1299756134998591 0.7601061322345518 0.6669384849315708 0.07350134055690054 0.23041870801835015 1.3343888841485459e-06 5.8747175844919 0.47245141090078835 IEWLESHQDADIEDFK ddPTM_PC-9_Lapatinib_30min_R1 2 IEWLESHQDADIEDFK 16 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 ; 124.78 2.8648e-05 4368200.0 33741.0 42375.0 40626.0 37669.0 42615.0 38131.0 45061.0 37394.0 37199.0 33939.6 False True 33259.84715265842 42276.88329101224 37285.88710089506 40439.30392010031 40108.469484313595 36500.22601770245 47394.03809483366 39131.46175350854 33009.25689716415 39806.0146383257 0.8355482822094791 1.0620727464212796 0.936689780166934 1.015909386747923 1.0075982197347806 0.9169525346694618 1.190625048135367 0.9830539959615126 0.8292529959877584 1.0 15.280698816179894 -5.762226774701096 24.99781384568609 0.9970169299969749 0.9565005194107769 0.03955279873448303 0.09943807460477669 91.88834147781151 2917386.1342069064 0.02762028714086284 0.04384130104709735 1.728913340170867e-06 5.762226774701096 -0.04051641058619804 IEYAKPTR ddPTM_PC-9_Lapatinib_30min_R1 2 IEYAKPTR 8 1 M0R1W6;B4DVF8;P14866;M0QXS5;A0A3B3ITJ4;P14866-2 M0R1W6;P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 0 ; 85.161 0.017414 18998700.0 113878.0 106689.0 122950.0 103756.0 114108.0 116705.0 94719.0 85851.0 106493.0 94732.0 False True 112254.07883733239 106441.96817545281 112841.525600725 111386.56235986971 107396.39178495947 111713.79920264242 99623.08635637366 89839.95087448406 94498.6369189953 111106.29997754454 1.0103304570489686 0.9580191960038772 1.0156177068584875 1.0025224706644162 0.9666093804461595 1.0054677297796855 0.8966466021864492 0.8085945701786615 0.8505245601563027 1.0 16.761581097542525 -7.352451559493718 4.441522361217015 0.8692345497934508 0.9917307659470848 0.5071054479356303 0.049313624984237366 0.1608944007931911 5.552126628807547 0.020390497088764982 0.01346445284561102 4.4416920051925364e-08 7.352451559493718 0.12249621615363393 IEYDCELVPR ddPTM_PC-9_Lapatinib_30min_R1 2 IEYDCELVPR 10 0 Q9P258 Q9P258 RCC2 Protein RCC2 0 ; 114.89 0.0053886 6491600.0 19617.8 24337.0 26567.0 25636.0 24642.0 23387.0 22767.8 23021.0 25738.0 21674.0 False True 19338.04657453609 24280.649171760833 24382.763811585664 27521.35695918904 23192.606008036026 22386.79252775976 23946.605280299027 24090.639702292337 22839.115406844572 25420.322021210362 0.7607317703686324 0.9551668602585521 0.9591839077113589 1.0826517829406568 0.9123647603159566 0.8806651823324871 0.9420260396512017 0.9476921528449342 0.8984589332813303 1.0 14.63369468587425 -4.760826744044245 24.602632605614023 0.9518504106415993 0.7607315034272125 0.5338139932473394 0.053928726261437104 10.226271664357297 410264.0979042211 0.014065476567443428 0.08116248620320808 1.7344958135792615e-05 4.760826744044245 -0.19111890721438674 IEYNDQNDGSCDVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IEYNDQNDGSCDVK 14 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 142.38 1.5895999999999998e-05 0.0 8265.4 10480.0 7070.1 11885.0 15062.0 9267.7 10543.0 8943.5 10424.0 8445.3 False True 9664.568970908702 11520.385140092863 7238.677997503565 11219.121981689883 12110.709223471686 8781.685497146582 9544.290715290046 8708.742601421534 10576.431279729475 9976.36603704199 0.9687464288122957 1.1547676876848716 0.7255826390718365 1.1245700027478516 1.213939943512992 0.8802489267675635 0.956690109389766 0.8729373570582913 1.0601486794349224 1.0 13.284298683885144 IEYNDQNDGSCDVK ddPTM_PC-9_Lapatinib_30min_R1 2 IEYNDQNDGSCDVK 14 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 177.42 0.00040638 18032100.0 61157.0 63353.0 57949.0 62258.0 65346.0 52081.0 56837.0 49369.0 51467.0 50978.0 False True 60284.88996517974 63206.310020896686 53184.656909608806 66836.66100659972 61502.476755179036 49853.61703674071 59779.741754423136 51662.863970395316 45670.244488463315 59789.47937608474 1.0082859157541546 1.0571476902034818 0.8895320291228727 1.117866582951612 1.0286504816059576 0.8338192196515716 0.9998371348644742 0.8640795087949872 0.7638508474240203 1.0 15.867604028065726 -6.747700089276135 24.831300927633986 0.8905423004034766 1.0204997222364156 0.3621638514091462 0.0849037111004025 240.39542560543705 434470.6362087347 0.02775772019645668 0.027614615652557323 1.7877216955830394e-07 6.747700089276135 0.129957421832939 IEYQFFEDR ddPTM_PC-9_Lapatinib_30min_R1 1 IEYQFFEDR 9 0 Q9NYU2-2;Q9NYU2 Q9NYU2-2 UGGT1 UDP-glucose:glycoprotein glucosyltransferase 1 0 89.029 0.044516 2150500.0 26908.0 25584.0 27186.0 26508.0 26120.0 29006.0 20209.0 20885.0 24992.0 20679.0 False True 26524.286985677158 25524.761819876283 24950.872020994768 28457.48674809576 24583.672953895824 27765.48099628849 21255.323136603572 21855.39334444097 22177.137782572827 24253.33759696452 1.0936345102868177 1.0524226497828855 1.0287603477765281 1.1733431175945621 1.013620201987072 1.1448107249273412 0.8763875508525404 0.9011293087833128 0.9143952948293786 1.0 14.565895675437224 -7.266735713188852 24.99909262709233 0.914738808607079 1.0812691361019644 0.6764915894208092 0.05455214090634397 246.49443532134447 1163465.3068424398 0.021182323919488894 0.014761189230202285 5.4108349528169074e-08 7.266735713188852 0.1665303274948854 IFAPNHVVAK ddPTM_PC-9_Lapatinib_30min_R1 1 IFAPNHVVAK 10 0 M0R117;Q02543;M0R3D6;M0R1A7 M0R117 RPL18A 60S ribosomal protein L18a 0 64.654 0.042681000000000004 7907700.0 95864.0 111740.0 104720.0 119100.0 132770.0 122070.0 106450.0 116140.0 116100.0 107770.0 False True 94496.96178069526 111481.27289528502 96110.32583088972 127859.01130595322 124960.72963586335 116849.35065906834 111961.46013614985 121536.28838991505 103023.59541280018 126397.90090550134 0.7476149611957865 0.881986742632946 0.7603791292605763 1.011559609692761 0.9886297853101812 0.9244564175668409 0.8857857554126267 0.9615372369259441 0.8150736260234538 1.0 16.947612979262196 -5.753930559283826 24.999979133553268 0.9383973558692491 0.8051929130241675 0.5111100560368274 0.06449670267761468 149.19062937202278 496711.7864238412 0.017369546588768808 0.029344520502674148 1.762257796850234e-06 5.753930559283826 -0.1332044428450816 IFAQDGEGQR ddPTM_PC-9_AZD4547_30min_R2 2 IFAQDGEGQR 10 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 107.21 0.010162000000000001 13655200.0 55770.0 60111.0 73144.0 81272.0 69082.0 62888.0 78672.0 82049.0 64274.0 68477.0 False True 73503.69991193697 79540.70521532725 72174.06276855941 62535.99603988305 59491.15674211936 58955.60341847771 85673.65559214145 69370.21234845193 67671.39242202844 66079.64107277669 1.1123501689572406 1.2037097042903917 1.092228432189434 0.9463731192336403 0.9002947924096453 0.892190127872321 1.2965212008004845 1.049797051289234 1.0240883776517289 1.0 16.011918229988233 -5.52974600348437 8.149809911783079 1.0193050608660488 1.1557785999796875 0.2198992039940879 0.10862867866457981 0.19865239144646826 109.20706114373114 0.031821512112811104 0.057650438662328836 2.952935742048884e-06 5.52974600348437 0.1364735391136387 IFDIDEAEEGVK ddPTM_PC-9_AZD4547_30min_R2 1 IFDIDEAEEGVK 12 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 0 123.96 0.0027023000000000004 0.0 2097.6 1235.4 3546.0 8698.5 5890.0 6325.3 3561.1 6775.2 5079.5 4860.0 False True 2764.5931672095935 1634.7188904362793 3498.9777230847617 6693.195215485321 5072.2751688006065 5929.777991077741 3878.0310012351933 5728.248518607566 5347.991999995224 4689.852879268873 0.5894839856129093 0.34856506856801966 0.7460740908423201 1.4271652838134998 1.0815424917106038 1.2643846499513576 0.8268982207049022 1.2214132652068554 1.1403325728266667 1.0 12.19532695075491 -5.550726873765732 5.755457697590022 1.1357490423394219 0.48416636162419907 0.7444564824365845 0.16005918465557242 0.07557497976090481 7.410690473363807 0.04220911126443423 0.07646105090744039 2.8136697808807583e-06 5.550726873765732 -0.6515826807152227 IFDT(ph)Y(ph)VGAQRT(ph)HR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IFDTYVGAQRTHR 13 1 V9GY58;D6RBS5;Q8IZ81 V9GY58 ELMOD2 ELMO domain-containing protein 2 3 IFDT(1)Y(1)VGAQRT(1)HR 78.964 0.023016 5337700.0 18074.0 19550.0 21830.0 24592.0 27212.0 25142.0 26565.0 30543.0 24412.0 13575.0 True False 21133.57122222807 21490.7947985511 22350.509990736027 23214.189968339728 21880.00394297647 23823.50926003856 24048.570886055186 29741.278612983497 24768.979317033372 16036.040040359136 1.317879674099066 1.3401559702060835 1.393767409814691 1.447626091598349 1.3644268714663583 1.4856229592892074 1.4996576976317282 1.8546523043177325 1.5445820323905015 1.0 13.969030304417885 -6.937288464118367 2.5028104493495413 1.5440546289441812 1.3749020764264221 0.018611685044135018 0.2012275189123745 0.6167922813983885 7.8332944868350465 0.07852789898040513 0.06520905202733539 1.1553445921744956e-07 6.937288464118367 -0.16915255251775907 IFDT(ph)Y(ph)VGAQRT(ph)HR ddPTM_PC-9_Lapatinib_30min_R1 1 IFDTYVGAQRTHR 13 1 V9GY58;D6RBS5;Q8IZ81 V9GY58 ELMOD2 ELMO domain-containing protein 2 3 IFDT(1)Y(1)VGAQRT(1)HR 70.563 0.044597000000000005 4540100.0 3474.8 7010.8 10854.0 9491.4 7821.6 8990.3 7418.8 7716.6 9325.5 7538.1 True False 3425.248714799723 6994.566923342265 9961.626017651623 10189.429218382227 7361.548865857261 8605.805826412898 7802.9091635328095 8075.141406833288 8275.163988131513 8841.05054111312 0.3874255326187143 0.7911465827297063 1.1267468692015212 1.1525133999629122 0.8326554442398217 0.9733917690430255 0.8825771470536572 0.9133689904024233 0.9359932905767147 1.0 13.110002093238533 -4.838237518703608 3.2083399218691664 0.9715197598279356 0.33955791929639456 0.7764147059662567 0.09591434924362523 0.1437577660847837 2.3928032810056665 0.02632394454032117 0.21244846376085874 1.4513176646702089e-05 4.838237518703608 -0.631961840531541 down IFFAGDTIPK ddPTM_PC-9_Lapatinib_30min_R1 2 IFFAGDTIPK 10 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 151.44 0.00054878 8527700.0 82338.0 73676.0 81971.0 70398.0 79354.0 70358.0 69199.0 64335.0 63084.0 73075.0 False True 81163.84502106023 73505.40774863993 75231.6607972105 75575.3037608438 74686.5537359667 67348.95235250858 72781.78562669258 67324.23896646433 55978.815616030086 85705.91638368311 0.9470039927898418 0.8576468329161236 0.8777884184846458 0.8817979778958643 0.8714282150792766 0.7858145060955282 0.8492037504256701 0.7855261551031227 0.6531499571794727 1.0 16.38710717831877 -6.667735295478276 4.90975692901626 0.8035960648095525 0.8863692637361325 0.1554828051100554 0.08282478442182634 0.3629373954684414 14.702051506362901 0.026872951762698622 0.026627079940469544 2.1491399859049968e-07 6.667735295478276 0.08277319892657997 IFGVTTLDIVR ddPTM_PC-9_Lapatinib_30min_R1 2 IFGVTTLDIVR 11 0 P40926;G3XAL0 P40926 MDH2 Malate dehydrogenase, mitochondrial;Malate dehydrogenase 0 ; 130.66 0.00091295 4647100.0 18373.2 18724.5 20187.2 15549.7 16702.6 12599.5 13937.2 16416.2 18276.8 13543.1 False True 18111.194798767785 18681.144570679848 18527.4863408455 16693.276810278574 15720.185906575052 12060.648755869028 14658.800020756653 17178.956582284503 16218.274320763732 15884.006789953575 1.1402157552729628 1.1760977452172474 1.1664239751247079 1.050948732963074 0.9896864257523399 0.7592951145989958 0.9228653836907291 1.0815253864755312 1.0210442827952944 1.0 13.95528726223501 -6.005122867945734 2.4775499376669337 0.9545435033597484 1.1633083665208566 0.5532838909891556 0.07980077919041449 0.23686771313571808 2.919771529430542 0.027758130111251778 0.042089390843037706 9.882734588036214e-07 6.005122867945734 0.2087648631611082 IFHELTQTDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IFHELTQTDK 10 0 V9GZ78;V9GYY3;A0A384N5Y3;F5H2F4;P11586;A0A494C1T2 V9GZ78 MTHFD1 C-1-tetrahydrofolate synthase, cytoplasmic;Methylenetetrahydrofolate dehydrogenase;Methenyltetrahydrofolate cyclohydrolase;Formyltetrahydrofolate synthetase;C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed 0 80.916 0.014268000000000001 2980800.0 27390.0 24952.0 28945.0 38065.0 38630.0 34532.0 42304.0 35973.0 39608.0 29362.0 False True 32026.58602284091 27429.06965797683 29635.158574523783 35932.34145839508 31060.728807775275 32721.081129888284 38296.658865562946 35028.74686654409 40187.19206902581 34685.09817053589 0.9233529011616487 0.7908027108101751 0.8544060745861776 1.0359590531278555 0.8955064406927518 0.9433757681471407 1.104124274847663 1.009907675461046 1.1586299070407073 1.0 15.082028347451185 -6.643975255169608 0.7106956288777909 1.0784692686992325 0.8538359750698925 0.528377032294913 0.07341966537035963 0.5547474389756128 0.6226385387443496 0.051580910825442694 0.05923830702791696 2.2699941858341037e-07 6.643975255169608 -0.22463329362934004 IFHELTQTDK ddPTM_PC-9_Lapatinib_30min_R1 1 IFHELTQTDK 10 0 V9GZ78;V9GYY3;A0A384N5Y3;F5H2F4;P11586;A0A494C1T2 V9GZ78 MTHFD1 C-1-tetrahydrofolate synthase, cytoplasmic;Methylenetetrahydrofolate dehydrogenase;Methenyltetrahydrofolate cyclohydrolase;Formyltetrahydrofolate synthetase;C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed 0 99.788 0.0046668 0.0 55730.0 36060.0 48800.0 42700.0 36789.0 47024.0 45053.0 35922.0 46577.0 43647.0 False True 54935.27998036966 35976.505285519794 44787.8523734475 45840.30044302433 34625.143349956874 45012.89313829795 47385.62389397798 37591.067259708325 41331.007782446155 51191.325794028235 1.0731364958470793 0.7027851833780141 0.8749109674098784 0.89547007685376 0.6763869232313592 0.8793070396225011 0.925657289765013 0.7343249403416221 0.8073830310381931 1.0 15.643611750436294 -4.742006348812442 24.954093619814355 0.8273354336422571 1.0731373472064927 0.34881450384732393 0.09820098722393863 1478.9749853411777 1899061.8871989076 0.023326941854885777 0.8763678322592559 1.8113136134103564e-05 4.742006348812442 0.24580191356423553 IFHGLK ddPTM_PC-9_AZD4547_30min_R2 1 IFHGLK 6 0 P13796;Q5TBN3 P13796 LCP1 Plastin-2 0 89.775 0.031674 2297400.0 28526.0 26677.0 34646.0 47275.0 40329.0 34049.0 30312.0 41358.0 32527.0 31446.0 False True 37596.674622340244 35299.818552831945 34186.57140270574 36376.479141469084 34730.01447921217 31919.9106474327 33009.709277875154 34967.07141229363 34246.31081481338 30345.085111417477 1.2389708080994746 1.1632796027172858 1.1265933602487372 1.1987601619144006 1.1445021278304093 1.0518972192772889 1.0878107329959374 1.1523141650091175 1.1285620287131128 1.0 14.889175246620837 -1.5228789394967126 0.029330020019293822 0.4878897439979189 2.0536571998526196 0.6098174800647821 0.041059088661766184 1105.7042472065702 2.4969963523518572 42.96863375652419 101.97249653946358 0.0299999865840111 1.5228789394967126 1.5657674558547008 IFHGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IFHGLK 6 0 P13796;Q5TBN3 P13796 LCP1 Plastin-2 0 ; 100.78 0.026488 3294400.0 85580.0 86799.0 82756.0 101837.0 101838.0 91379.0 97006.0 92669.0 89438.0 71914.0 False True 100067.00371795261 95415.8310853932 84729.21689387785 96131.40305000867 81883.57495019997 86586.9243764641 87816.88941737906 90236.53694092177 90745.86154992745 84951.43892908939 1.17793182763485 1.123180870014911 0.9973841286502865 1.131604176007559 0.9638868509166723 1.0192520040624606 1.033730452649325 1.0622131664684804 1.0682086459497735 1.0 16.374350763901617 -5.057147131021305 3.8896330455424395 1.0373083138324473 1.170387359255108 0.5392391436338616 0.04407302209038732 0.1588458645474998 4.748905559383573 0.011135439680533387 0.038833788596122944 8.767037596400669e-06 5.057147131021305 0.1330790454226607 IFHGLK ddPTM_PC-9_Lapatinib_30min_R1 1 IFHGLK 6 0 P13796;Q5TBN3 P13796 LCP1 Plastin-2 0 84.566 0.035411 2019400.0 39543.0 38188.0 33571.0 29939.0 34638.0 33324.0 31333.0 29355.0 36607.0 28203.0 False True 38979.10956870192 38099.57803226373 30810.921967807502 32140.813933576228 32600.660940928137 31898.810202038134 32955.26942645355 30718.94046569616 32483.93417120052 33077.85097186471 1.1784051388905732 1.1518153964920632 0.9314668596220048 0.9716717679426784 0.9855737293410488 0.9643555812973025 0.9962941502603835 0.9286861015192617 0.9820448794823653 1.0 15.013577886944196 -5.2388114359698275 10.332537494589111 0.968817091232822 1.1653798962263562 0.9161939461237547 0.02360038351849885 0.1361162139357261 60.44657086328771 0.005727354739709486 0.014758209795701019 5.7701694095334975e-06 5.2388114359698275 0.19656280499353418 IFIGCLAAVTSGMMYALYLS(ph)AYHERK ddPTM_PC-9_Lapatinib_30min_R1 1 IFIGCLAAVTSGMMYALYLSAYHERK 26 1 H0YBV9;Q7Z388 H0YBV9 DPY19L4 Probable C-mannosyltransferase DPY19L4 1 IFIGCLAAVT(0.002)S(0.011)GMMY(0.01)ALY(0.063)LS(0.473)AY(0.442)HERK 42.903999999999996 0.020287 2959100.0 4389.3 7223.2 8167.7 10709.0 7612.5 7867.1 7878.0 6918.5 11084.0 6652.0 True False 4326.707777100964 7206.475124192085 7496.18323423376 11496.57558417675 7164.747716750843 7530.642472105813 8285.884292649951 7239.95876722599 9835.60320030558 7801.789336767152 0.5545789036767088 0.9236951695466121 0.9608287164210939 1.4735819038329245 0.9183467288697286 0.9652455541982508 1.0620492216575788 0.9279869597486505 1.2606855652912548 1.0 12.929589328025262 -4.744565734548895 1.9282755477240712 1.0727794633254193 0.3665761769350981 0.4783225650948003 0.1638593642998792 0.7845746144007547 2.893456434385464 0.04427338711145692 1.0348485680413055 1.8006705654118417e-05 4.744565734548895 -0.7062032863903211 IFLGADAEEEIGT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 IFLGADAEEEIGTPR 15 0 P28749;P28749-2;H0YE05 P28749 RBL1 Retinoblastoma-like protein 1 1 IFLGADAEEEIGT(1)PR;IFLGADAEEEIGT(1)PR 121.13 0.00017287 5880900.0 14242.1 8704.6 16072.4 20837.2 18999.1 13256.599999999999 14117.2 17366.8 16615.6 16139.1 True False 18770.791545917127 11518.191722269412 15859.269474480401 16033.505471530812 16361.402913337786 12427.662706357198 15373.603451359822 14683.160109362661 17493.86669458029 15574.075021359724 1.2052588368922796 0.7395746910472886 1.0183121278618175 1.0294996941738743 1.0505537497988322 0.797971159719775 0.9871278666806885 0.9427950031847683 1.1232684233630303 1.0 13.926858860505 -8.245827282386436 24.28855195315085 1.061634223687721 0.9645439527820487 0.07356614916897497 0.12624970437387742 1204.002852203142 1873140.3108184026 0.08145584265847865 0.030523366374458006 5.6777036108498595e-09 8.245827282386436 -0.09709027090567224 IFLGADAEEEIGT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IFLGADAEEEIGTPR 15 0 P28749;P28749-2;H0YE05 P28749 RBL1 Retinoblastoma-like protein 1 1 IFLGADAEEEIGT(1)PR 125.33 0.00030037 0.0 3014.2 1710.4 3889.0 4813.8 5086.2 4141.9 3560.9 4015.5 1465.5 3026.7 True False 3524.4445268363315 1880.1972083601945 3981.728509114631 4544.098392550169 4089.595621592202 3924.6914726017685 3223.5857733165435 3910.097379773937 1486.930165046387 3575.4167506559816 0.9857436972038859 0.5258679867221729 1.1136403912590338 1.270928316738591 1.1438094932127518 1.0976878350983017 0.9015972117726171 1.093606047198988 0.4158760415197976 1.0 11.80389569692033 -8.231464487620993 24.862041904542608 0.7079376820049601 1.0150724879995086 0.2238838096052459 0.22987001185861783 866.8938185667066 719029.0835166821 0.15971643467306382 0.060349191165899464 5.8686135547097865e-09 8.231464487620993 0.30713480599454845 IFLGADAEEEIGT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 IFLGADAEEEIGTPR 15 0 P28749;P28749-2;H0YE05 P28749 RBL1 Retinoblastoma-like protein 1 1 IFLGADAEEEIGT(1)PR 127.07 5.3343999999999996e-05 3154200.0 5448.8 5265.6 5861.7 4286.5 4142.2 4291.1 3750.6 4558.5 4776.7 3153.0 True False 5371.0991128124615 5253.407826717503 5379.773652816341 4601.7435093448175 3898.563939878534 4107.579656042669 3944.7877161732576 4770.304551622419 4238.697745119063 3697.9918488915882 1.4524367095136674 1.420610980603466 1.4547824529220743 1.2443898465390382 1.0542381106240306 1.1107595213531494 1.0667378072657576 1.2899716242079438 1.1462160865469573 1.0 11.852526329421329 -5.916723333299814 3.409873335965895 1.124251043931294 1.441111686097765 0.8025879911246053 0.07320590180511602 0.10689933048030188 2.4762088168088314 0.02211387516179534 0.03420982155897975 1.2113695891215864e-06 5.916723333299814 0.31686064216647103 IFPGLS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 2 IFPGLSPVR 9 0 Q5VZK9-2;Q5VZK9;A0A0U1RR91;Q5VZK9-3 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 IFPGLS(1)PVR;IFPGLS(1)PVR 94.40899999999999 0.005756600000000001 20840500.0 33533.0 30353.0 39638.0 49477.0 44346.0 44894.0 35428.0 50505.0 34258.0 37945.0 True False 44195.79647027044 40164.013664734004 39112.374220990896 38070.84206202992 38189.323367679404 42086.771083022824 38581.02336686992 42700.61273944316 36068.80794090687 36616.55709955913 1.2069894050962688 1.0968812156623426 1.0681608900215747 1.0397165948321312 1.0429523251966037 1.1493918166197432 1.0536496717036905 1.1661558628612103 0.9850409431677873 1.0 15.160208526531214 -1.5228787455881658 0.011803206105872774 2.0656366977117224e-09 2.3359268018092663 0.2704710156493425 0.05910663867643473 14718.033647012526 13.473833059067216 1118.6800364450335 1585.4656666010853 0.029999999978735977 1.5228787455881658 2.3359267997436297 IFPGLS(ph)PVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IFPGLSPVR 9 0 Q5VZK9-2;Q5VZK9;A0A0U1RR91;Q5VZK9-3 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 IFPGLS(1)PVR;IFPGLS(1)PVR;IFPGLS(1)PVR;IFPGLS(1)PVR 98.04 0.0045899999999999995 22898400.0 43777.1 52047.0 54515.299999999996 49710.9 53868.799999999996 45674.7 46756.1 45130.8 43597.7 39447.2 True False 51187.69839286273 57213.88219336009 55815.151502426575 46925.75943791229 43313.5953404164 43279.438326286 42327.02372315021 43946.164320035234 44235.233883754954 46598.66509613662 1.0984799304284487 1.2278008838949241 1.1977843439780012 1.0070193929611686 0.9295029214046612 0.9287699172711751 0.9083312501726458 0.9430777518920538 0.9492811391162016 1.0 15.508001006386765 -5.881336980401706 3.6273327496470134 0.9395203146922911 1.1805879245196913 0.878161414903018 0.0384604305405645 0.06868842980559624 1.7315996746289481 0.011039939070376535 0.017273981284169838 1.3142047108044219e-06 5.881336980401706 0.24106760982740016 IFPGLS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 4 IFPGLSPVR 9 0 Q5VZK9-2;Q5VZK9;A0A0U1RR91;Q5VZK9-3 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 IFPGLS(1)PVR;IFPGLS(1)PVR;IFPGLS(1)PVR;IFPGLS(1)PVR 107.45 0.0025013 18580300.0 56004.4 56570.7 59844.9 45166.4 56833.1 54543.9 48487.9 50934.7 54929.0 45350.1 True False 55205.76698605087 56439.71401984344 54924.68332999445 48488.08772669351 53490.2887961737 52211.18454504107 50998.36620888321 53301.31210826419 48742.31759198715 53188.80435979017 1.0379208115417893 1.0611201868359896 1.0326361720497061 0.9116220661532614 1.0056681935232867 0.9816198196873144 0.9588176839605199 1.0021152524451005 0.9164018288938172 1.0 15.69883498628369 -5.584838777204797 9.482321170753163 0.9699193155149871 1.0488745467007874 0.5501818444641806 0.03164373211117166 0.23053781338520063 33.228515370579345 0.008073978351880333 0.014006868518275232 2.6011249975201078e-06 5.584838777204797 0.07895523118580028 IFQGSFGGPTLYENPHY(ph)QSPNMHR ddPTM_PC-9_Lapatinib_30min_R1 1 IFQGSFGGPTLYENPHYQSPNMHR 24 0 Q8TDN6 Q8TDN6 BRIX1 Ribosome biogenesis protein BRX1 homolog 1 IFQGSFGGPT(0.002)LY(0.048)ENPHY(0.71)QS(0.239)PNMHR 62.707 0.0027665 5806400.0 26294.0 21505.0 25910.0 18220.0 25340.0 23029.0 19907.0 23320.0 23914.0 19381.0 True False 25919.042738270957 21455.206493763253 23779.779815492333 19559.959580138242 23849.55102035681 22044.103353220988 20937.687054300925 24403.53233384551 21220.55349441608 22730.980026440793 1.140251881270486 0.9438751197179552 1.0461396643625382 0.8604978561146944 1.0492090966872034 0.969782355515652 0.921107978184227 1.0735802990218282 0.9335520716542896 1.0 14.472372265588472 -4.753826240819138 24.849801235968677 0.9785484538295596 1.1402521939257382 0.3756593845666861 0.06292204544699768 261.1770916434373 852423.8825512297 0.014490300488747844 0.14880789779946857 1.7626811457899156e-05 4.753826240819138 0.1617037400961786 IFQGSFGGPTLYENPHYQS(ph)PNMHR ddPTM_PC-9_AZD4547_30min_R2 4 IFQGSFGGPTLYENPHYQSPNMHR 24 0 Q8TDN6 Q8TDN6 BRIX1 Ribosome biogenesis protein BRX1 homolog 1 IFQGSFGGPTLYENPHY(0.004)QS(0.996)PNMHR;IFQGSFGGPTLY(0.001)ENPHY(0.001)QS(0.998)PNMHR;IFQGSFGGPTLYENPHY(0.035)QS(0.965)PNMHR;IFQGSFGGPTLYENPHY(0.027)QS(0.973)PNMHR 109.32 9.355200000000001e-07 23475300.0 59807.2 58158.799999999996 70772.4 98213.3 80053.2 79253.7 62177.9 85539.8 73946.2 63872.399999999994 True False 78824.64553296035 76957.49474267894 69833.91173413537 75571.74106535898 68939.19499881625 74297.953610339 67711.61264544705 72321.589419056 77854.8451678407 61636.246717245514 1.2788683563839653 1.2485752919985411 1.133000717167228 1.2260925200725172 1.1184846364035241 1.2054263127211282 1.0985680707664127 1.1733613461382422 1.2631341023245224 1.0 15.91149139248457 -14.522878745280336 0.19416393257281306 0.21305564120956702 1.219900608358563 0.47470705450527917 0.060173984658700115 128.9374489898199 1.264164230299386 39.66643317036689 0.15696517680246813 3.0000000000000132e-15 14.522878745280336 1.006844967148996 IFQGSFGGPTLYENPHYQS(ph)PNMHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IFQGSFGGPTLYENPHYQSPNMHR 24 0 Q8TDN6 Q8TDN6 BRIX1 Ribosome biogenesis protein BRX1 homolog 1 IFQGSFGGPTLYENPHY(0.177)QS(0.822)PNMHR;IFQGSFGGPTLY(0.001)ENPHY(0.099)QS(0.9)PNMHR 102.66 1.6513e-06 14300400.0 41514.0 35950.0 47457.0 51007.0 62965.0 47819.0 49635.0 42764.0 45324.0 34726.0 True False 48541.50026112517 39518.87841472696 48588.55486167473 48149.2431569252 50627.46024803444 45311.28745946158 44933.213473719195 41641.49031220336 45986.77775541622 41021.54890913523 1.183317099231114 0.9633687529026084 1.184464169534427 1.1737548785292864 1.2341674459971461 1.104572807814457 1.0953563351117848 1.0151125791091247 1.1210395262567783 1.0 15.324094346290181 -7.346895635939347 2.553965519665141 1.0522332789960143 1.1416147356773425 0.24768725407881875 0.07426489150633755 0.47729345784676364 6.081179786504015 0.03736206292396703 0.023342580306930195 4.4988795318736074e-08 7.346895635939347 0.08938145668132824 IFQGSFGGPTLYENPHYQS(ph)PNMHR ddPTM_PC-9_Lapatinib_30min_R1 1 IFQGSFGGPTLYENPHYQSPNMHR 24 0 Q8TDN6 Q8TDN6 BRIX1 Ribosome biogenesis protein BRX1 homolog 1 IFQGSFGGPTLY(0.005)ENPHY(0.024)QS(0.97)PNMHR 96.387 0.0010608 0.0 5513.2 5065.5 8404.3 5579.3 6162.6 6169.4 6004.2 4815.8 6326.4 5116.4 True False 5434.580757002942 5053.771145973393 7713.330895536164 5989.620333999197 5800.127984137766 5905.5491435738195 6315.068097223772 5039.559648942246 5613.854212054606 6000.7629228255355 0.9056483028734621 0.842188103574297 1.2853917068105474 0.9981431379693481 0.9665650949274134 0.984133054333884 1.052377535730114 0.8398198218718005 0.9355234133147943 1.0 12.55093021788425 -7.749360845677632 24.99640404796299 0.9157536924709355 1.006913917121776 0.08988464513668226 0.11510183338006938 500.8542946003387 1036517.5154943438 0.056204220583318476 0.03213304932591739 1.7808984434290692e-08 7.749360845677632 0.0911602246508405 IFSLS(ph)GTLETVR ddPTM_PC-9_AZD4547_30min_R2 2 IFSLSGTLETVR 12 0 B4DEM9;Q9Y2S7 B4DEM9 POLDIP2 Polymerase delta-interacting protein 2 1 IFS(0.031)LS(0.839)GT(0.13)LETVR;IFS(0.003)LS(0.498)GT(0.498)LET(0.001)VR 122.34 0.00040512 16823300.0 38821.0 29703.0 47671.0 48770.0 46052.0 43522.0 39547.0 50163.0 43840.0 45139.0 True False 51165.27047303763 39303.9138761768 47038.851392321914 37526.829988988815 39658.47471538293 40800.56245991264 43066.606387309606 42411.46098106499 46157.292898866144 43558.697349242306 1.174628113022017 0.9023206906544573 1.0798957327666767 0.8615232381287359 0.9104605309339624 0.9366800419393707 0.9887028081214816 0.9736622893246997 1.05965732925365 1.0 15.41067318952968 -10.802888991890173 14.74736696697073 0.999999999899407 0.9798775728189278 0.0 0.09006680863767301 0.0 0.0 0.08383619323736924 0.020333263527492144 1.5743852347522747e-11 10.802888991890173 -0.020122427080479177 IFSLS(ph)GTLETVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IFSLSGTLETVR 12 0 B4DEM9;Q9Y2S7 B4DEM9 POLDIP2 Polymerase delta-interacting protein 2 1 IFS(0.036)LS(0.927)GT(0.036)LETVR;IFS(0.002)LS(0.707)GT(0.292)LETVR 119.21 0.00054913 6917500.0 21819.7 18381.2 22083.4 24753.8 27415.3 21606.8 23192.9 25394.2 29687.9 21718.0 True False 25513.34425128085 20205.96405888121 22609.952007760883 23366.924838902396 22043.468767377733 20473.701371402472 20995.90060994502 24727.629157378986 30122.029373511185 25655.301480406597 0.9944667487445368 0.7875940991889282 0.8812974591247154 0.9108029721166258 0.8592169062683873 0.798030044084206 0.8183844818966542 0.9638409112543039 1.174105453273114 1.0 14.646969358566674 -8.010683419837575 4.828865962490578 1.0853017863306542 0.8619837395699281 0.6264141856219294 0.06872658742356398 0.11066817232859967 7.070877604917219 0.04302963384262287 0.017326195084617264 9.757006182115569e-09 8.010683419837575 -0.22331804676072609 IFSLS(ph)GTLETVR ddPTM_PC-9_Lapatinib_30min_R1 1 IFSLSGTLETVR 12 0 B4DEM9;Q9Y2S7 B4DEM9 POLDIP2 Polymerase delta-interacting protein 2 1 IFS(0.107)LS(0.447)GT(0.447)LETVR 110.8 0.0011493 3296900.0 21649.0 18947.0 18483.0 19342.0 17802.0 20419.0 17206.0 13271.0 20373.0 14127.0 True False 21340.281290059615 18903.1293856002 16963.39908644324 20764.47520302052 16754.921360078624 19545.72696901383 18096.84249039542 13887.619108167406 18078.378202799136 16568.83312695574 1.287977320221859 1.1408847708681917 1.0238137445446045 1.2532249582041426 1.0112312213960402 1.1796682855846379 1.0922219055338165 0.8381772573696646 1.0911075067433402 1.0 14.016184382758677 -7.5390546630721955 24.0862280689386 0.9718252124076361 1.1413102510343474 0.374809041050598 0.09955776915353594 162.3582581377828 241749.78814305362 0.04435898728869777 0.02562182730972373 2.8903160658635044e-08 7.5390546630721955 0.16948503862671127 IFSLSGT(ph)LETVR ddPTM_PC-9_AZD4547_30min_R2 1 IFSLSGTLETVR 12 0 B4DEM9;Q9Y2S7 B4DEM9 POLDIP2 Polymerase delta-interacting protein 2 1 IFS(0.003)LS(0.292)GT(0.706)LETVR 130.15 0.00074316 0.0 3603.3 3163.9 5535.9 6874.9 5588.3 5083.1 6150.4 8173.8 4215.5 5429.7 True False 4749.074446704011 4186.568801563335 5462.490348907198 5289.99802114618 4812.461006079528 4765.252953448418 6697.773685096438 6910.727025238297 4438.322723886185 5239.607855672057 0.9063797477826463 0.7990233080193644 1.0425380103577528 1.0096171635095885 0.9184773247619804 0.9094674801454592 1.2782967484572088 1.3189397404535141 0.8470715454557437 1.0 12.355243125843224 -7.2384253621226895 24.562276534976792 1.1376553303290988 0.9330074765929185 0.27963709165259376 0.13904100951375856 747.4256371908862 797709.399402843 0.053343913976329684 0.04129209063807352 5.775301185484874e-08 7.2384253621226895 -0.20464785373618033 IFSNQPDS(ph)PISASQDKR ddPTM_PC-9_Lapatinib_30min_R1 2 IFSNQPDSPISASQDKR 17 1 O75161;O75161-2;D6RA06 O75161 NPHP4 Nephrocystin-4 1 IFS(0.09)NQPDS(0.868)PIS(0.036)AS(0.007)QDKR;IFS(0.002)NQPDS(0.99)PIS(0.007)AS(0.002)QDKR 63.225 0.01201 8116700.0 31698.0 67291.0 35806.0 39081.0 35307.0 39298.0 33292.0 32843.0 42070.0 35833.0 True False 31245.980707298717 67135.19182384665 32862.16889515702 41955.147110394246 33230.31167623278 37617.31614811232 35015.69686099294 34369.00567926621 37331.63358326018 42026.68630552877 0.743479523466217 1.5974419523771675 0.7819357599657786 0.9982977674086784 0.7906954984424076 0.895081660129926 0.833177676832125 0.8177900448635855 0.8882840134447875 1.0 15.359018087786978 IFTSIGEDYDER ddPTM_PC-9_AZD4547_30min_R2 2 IFTSIGEDYDER 12 0 D6RBK0;C9JZ20;E7ESE2;E9PCW0;C9JW96;P35232-2;P35232 D6RBK0 PHB Prohibitin 0 ; 208.33 2.3099e-07 26707000.0 25152.5 23492.0 35104.0 52400.0 39224.0 30469.0 29807.0 39978.0 24739.0 32144.0 False True 33150.4717954993 31085.329588901626 34638.498023453874 40319.98957192977 33778.42465552374 28563.768613369775 32459.765256189763 33800.318703048375 26046.65303433052 31018.648343872126 1.0687271549679993 1.002149714722907 1.116699143026871 1.2998628800630885 1.0889715206496682 0.9208579399305991 1.046459694063437 1.0896773556455042 0.8397094788134492 1.0 14.920848200995056 -6.592512592600753 7.503007698485175 0.9900284457703811 1.1228832987394473 0.3417471877167719 0.09460015804325678 0.30986647411974505 28.401895954836597 0.032931896920435445 0.03293264595325093 2.55556779993483e-07 6.592512592600753 0.13285485296906618 IFTSIGEDYDER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IFTSIGEDYDER 12 0 D6RBK0;C9JZ20;E7ESE2;E9PCW0;C9JW96;P35232-2;P35232 D6RBK0 PHB Prohibitin 0 ;;; 221.5 7.384799999999999e-11 20328300.0 45752.6 44580.2 52431.3 60883.0 57559.0 49997.2 47094.3 50631.2 45023.5 40462.1 False True 53497.61152495915 49005.82763572216 53681.46103881253 57471.92289534917 46280.727140738745 47375.25881695962 42633.18697079426 49302.18464819077 45681.8835114064 47797.558432192614 1.1192540640094168 1.025278889616164 1.1231004846192518 1.2024029004929397 0.9682655068332475 0.9911648287258839 0.8919532371360617 1.031479143817203 0.9557367574792007 1.0 15.544649304706692 -6.2877173390255 24.41018116738664 0.9715197573853096 1.111320596956417 0.6464256025761699 0.05223368318130545 367.005026392294 340917.98465440713 0.016516731410302094 0.018734292743746463 5.155640907835177e-07 6.2877173390255 0.13980083957110745 IFTSIGEDYDER ddPTM_PC-9_Lapatinib_30min_R1 3 IFTSIGEDYDER 12 0 D6RBK0;C9JZ20;E7ESE2;E9PCW0;C9JW96;P35232-2;P35232 D6RBK0 PHB Prohibitin 0 ;; 265.67 2.7641999999999998e-50 24261700.0 79679.0 73673.0 63246.0 55724.0 70540.0 66786.0 56988.0 57531.0 65727.0 48549.0 False True 78542.76284866087 73502.41469495563 58046.15801662014 59822.128849814646 66390.975886976 63929.71846576995 59938.5597955745 60204.100287241214 58324.13312400624 56940.629962523846 1.379379941886044 1.2908605813341392 1.019415451757803 1.050605321528534 1.1659684118470766 1.1227434348345997 1.05265009949879 1.0573135619831613 1.0242972928538543 1.0 15.797170833971068 -5.134851102517678 4.008212148326065 1.0691364247643607 1.3615860316547252 0.838363038605656 0.04848124648721279 0.088641180577821 2.382869198740029 0.01341390340832097 0.04149745036678138 7.33075824462578e-06 5.134851102517678 0.2924496068903646 IFTT(ph)PLTPSQYYSGSK ddPTM_PC-9_Lapatinib_30min_R1 1 IFTTPLTPSQYYSGSK 16 0 P49454 P49454 CENPF Centromere protein F 1 IFT(0.024)T(0.839)PLT(0.099)PS(0.037)QYYSGSK 138.01 3.5608e-05 8402300.0 45247.0 57109.0 59319.0 52512.0 57877.0 48008.0 50776.0 42612.0 56002.0 41036.0 True False 44601.76948271644 56976.767619266524 54442.02079796173 56373.907654896815 54472.78865056005 45954.80975211399 53404.93283112392 44591.90908275409 49694.4650327962 48129.017922967054 0.9267126446274853 1.183833996165489 1.1311683293662664 1.1713080816468378 1.1318076079953787 0.9548254199923009 1.1096202485702333 0.9265077703045118 1.0325260555354512 1.0 15.554619364827708 -6.749114211958892 24.99295311221745 1.0066604052394048 1.117822374860339 0.29317005798806706 0.08033699712788442 271.9616141492542 551482.0219794892 0.025769897959386775 0.02559197657916477 1.7819100942003717e-07 6.749114211958892 0.11116196962093428 IFTTPLT(ph)PSQYYSGSK ddPTM_PC-9_AZD4547_30min_R2 2 IFTTPLTPSQYYSGSK 16 0 P49454 P49454 CENPF Centromere protein F 1 IFT(0.001)T(0.006)PLT(0.906)PS(0.087)QYYSGSK;IFT(0.002)T(0.03)PLT(0.628)PS(0.339)QYYS(0.001)GSK 153.72 7.5453e-05 20565000.0 56540.0 65802.0 82696.0 85526.0 97641.0 98370.0 79830.0 123516.0 91124.0 89632.0 True False 74518.54389494212 87071.20967175647 81599.39700739342 65809.30206352795 84085.23255634295 92218.9083493774 86934.71534879807 104429.44031531639 95940.62860666703 86494.01096185757 0.8615457078040186 1.0066732794962352 0.9434109494977335 0.7608538594949513 0.9721509226046084 1.0661883675396255 1.005095201182598 1.2073603611857942 1.1092170144471074 1.0 16.400312620336273 -6.683365269291501 3.1411755956102345 1.0890127847275595 0.9013627123619337 0.5362841448976203 0.0803600743212776 0.2036230677687007 4.0426176569021655 0.029593539442254953 0.028793857532686304 2.0731691168480186e-07 6.683365269291501 -0.1876500723656258 IFTTPLT(ph)PSQYYSGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IFTTPLTPSQYYSGSK 16 0 P49454 P49454 CENPF Centromere protein F 1 IFTT(0.003)PLT(0.613)PS(0.364)QY(0.019)YSGSK;IFT(0.06)T(0.008)PLT(0.649)PS(0.283)QYYSGSK 163.9 4.3421e-05 14693300.0 76184.0 81373.0 107003.0 93917.0 120951.0 88730.0 108595.0 74394.0 75566.0 70341.0 True False 89080.44649741198 89451.1736645781 109554.35733113713 88655.13497302198 97251.5198040185 84076.84259976208 98308.0954402849 72441.23632695865 76671.0097931733 83093.26648095055 1.072053732751426 1.0765153116839512 1.318450483063545 1.0669352491196926 1.1703898994789643 1.0118370135206687 1.1831054380660604 0.871806337563659 0.922710263300943 1.0 16.34244395151334 -7.762019068164901 24.999999434085026 0.9229436963477913 1.1285380593195335 0.5279047547705176 0.08524059763768986 11.611910396150922 500694.8528110574 0.04260996563625544 0.022406734571845575 1.7297404114403485e-08 7.762019068164901 0.20559436297174227 IFTTPLT(ph)PSQYYSGSK ddPTM_PC-9_Lapatinib_30min_R1 1 IFTTPLTPSQYYSGSK 16 0 P49454 P49454 CENPF Centromere protein F 1 IFTTPLT(0.838)PS(0.162)QYYSGSK 152.94 7.7031e-05 8331800.0 48144.0 38564.0 56417.0 53376.0 55464.0 52182.0 42663.0 37182.0 55218.0 41333.0 True False 47457.457731471724 38474.70742736511 51778.6120359178 57301.44909711627 52201.71656641954 49950.29750218323 44871.8813883378 38909.611459564505 48998.76736868225 48477.353977239465 0.9789613879039976 0.7936635206085983 1.0680989738059612 1.1820250982349365 1.0768268538528052 1.0303841568092873 0.9256256314939454 0.8026348030016841 1.0107558137700254 1.0 15.56502333438146 -7.278119495568773 7.837213016616631 0.918057481642223 1.023242813454831 0.1302957200833793 0.10653349624478319 0.3846991482687154 138.67424204400191 0.047999350925422415 0.03337191200279172 5.2708481475938247e-08 7.278119495568773 0.10518533181260803 IFVGGIKEDTEEYNLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IFVGGIKEDTEEYNLR 16 1 P51991;P51991-2 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 0 70.628 0.025177 4931400.0 14098.0 11890.0 10281.0 16024.0 16383.0 16440.0 18871.0 19352.0 21190.0 14812.0 False True 16484.512951807654 13070.360621727501 10526.138030909622 15126.227230508932 13172.868756349533 15577.857459034034 17083.402265791367 18844.03050513888 21499.86366245851 17497.298348272514 0.9421176128847999 0.7469930706769895 0.60158647474562 0.8644893016870987 0.752851582807358 0.8903007280876603 0.976345143447702 1.0769680055778055 1.228753332915602 1.0 14.094844561010428 -7.330968436914941 1.43189937390834 1.1211540811354375 0.772104454393717 0.6649701714874302 0.09887822822902403 0.24596529550101404 0.9771360255888295 0.06191970250045484 0.034362914799790326 4.666932968054629e-08 7.330968436914941 -0.34904962674172046 IFVGGLNPEATEEK ddPTM_PC-9_Lapatinib_30min_R1 1 IFVGGLNPEATEEK 14 0 Q99729-3;D6R9P3;D6RD18;D6RBZ0;Q99729-2 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 0 213.63 1.345e-14 9329800.0 56218.0 43972.0 55235.0 46149.0 43838.0 39952.0 45577.0 40266.0 48307.0 48630.0 False True 55416.32101088146 43870.18553563162 50693.79151326585 49542.95140855102 41259.535028824095 38243.346092660766 47936.75405002625 42136.905358260025 42866.15696473852 57035.630704598116 0.9716088053430413 0.7691715686085134 0.8888091687075708 0.8686316044289303 0.7233992947762358 0.6705167562840267 0.8404703070314548 0.7387821408778253 0.751568036246555 1.0 15.799575845864053 -1.5228788052535982 0.7894922251341472 0.7854933431457292 38.31932252370999 0.17683476517674335 0.09445831344324171 767.3327627569117 2.792076536618395 0.03330587647976976 51456.72340835731 0.02999999585719421 1.5228788052535982 37.53382918056426 IFVGGLS(ph)PDTPEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IFVGGLSPDTPEEK 14 0 Q14103-3;Q14103;D6RAF8;H0YA96;H0Y8G5;Q14103-4;Q14103-2;D6RF44 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 IFVGGLS(0.705)PDT(0.295)PEEK;IFVGGLS(0.996)PDT(0.004)PEEK;IFVGGLS(0.737)PDT(0.263)PEEK 151.3 2.5168e-08 2057900.0 23242.3 28928.0 27363.6 29019.5 33858.7 28790.9 32042.1 25631.0 30577.7 22654.8 True False 27176.762333650076 31799.780661508255 28016.052001030883 27393.6314974884 27224.330791711644 27281.054520517228 29006.840323285116 24958.21340828932 31024.84101517498 26761.93590470188 1.0155006136486304 1.1882466490744887 1.0468619348314283 1.023604256247977 1.0172780806536692 1.0193976481247062 1.0838842311922892 0.932601195114003 1.1592898632465576 1.0 14.7078948609658 -5.498088574104829 24.123536496862688 1.0319920343442364 1.1057938186582477 0.13703352064703178 0.06722824737782164 771.6895059479785 750935.133661834 0.016073283760132274 0.033181193339605106 3.176226215113728e-06 5.498088574104829 0.0738017843140113 IFVGGLS(ph)PDTPEEK ddPTM_PC-9_Lapatinib_30min_R1 1 IFVGGLSPDTPEEK 14 0 Q14103-3;Q14103;D6RAF8;H0YA96;H0Y8G5;Q14103-4;Q14103-2;D6RF44 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 IFVGGLS(0.999)PDT(0.001)PEEK 135.86 3.3868e-05 0.0 9641.7 6487.6 6270.5 7398.9 9138.2 8354.4 7382.4 7253.7 6614.5 6864.9 True False 9504.207589928765 6472.578360796954 5754.963694829971 7943.039788006853 8600.709042392447 7997.101787057593 7764.624549639383 7590.7333829337595 5869.50535622711 8051.48881809573 1.1804285896253186 0.8038983232827484 0.7147701282147575 0.9865305619197859 1.0682134989819951 0.9932450963707605 0.9643712765505407 0.9427738837410515 0.7289962749541911 1.0 12.975039864396656 -12.249503376729304 2.118925139857958 3.42275422759202 0.9301025420261579 0.021349240679237713 0.13891834889767607 8361823.243952184 642461.7405287185 99143496.05640973 0.03598221406051905 5.629847400545822e-13 12.249503376729304 -2.4926516855658623 IFVGGLSPDTPEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IFVGGLSPDTPEEK 14 0 Q14103-3;Q14103;D6RAF8;H0YA96;H0Y8G5;Q14103-4;Q14103-2;D6RF44 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 0 ; 167.2 0.00014309 6555500.0 35172.0 34563.0 33013.0 39972.0 46249.0 34186.0 38309.0 37274.0 34289.0 29143.0 False True 41125.92492133486 37994.18622109065 33800.15512249971 37732.498430972475 37186.84045122443 32393.22597898646 34680.094186858216 36295.59699506753 34790.4117565852 34426.39520413895 1.1946044503779603 1.103635335497536 0.981809304229333 1.0960339648467188 1.080183976007851 0.9409415591409915 1.0073693159337451 1.0542956002173545 1.010573763250196 1.0 15.071227503431958 -4.94327340769884 3.0139718791252 1.024801699165319 1.1979480720261302 0.6057314339621247 0.04402438086127347 0.20530326161669119 3.3722548557686056 0.011865783928786696 0.07160932056799131 1.1395321754963574e-05 4.94327340769884 0.17314637286081114 IFVGGLSPDTPEEK ddPTM_PC-9_Lapatinib_30min_R1 2 IFVGGLSPDTPEEK 14 0 Q14103-3;Q14103;D6RAF8;H0YA96;H0Y8G5;Q14103-4;Q14103-2;D6RF44 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 0 ; 137.89 6.4886e-05 19376000.0 80379.0 85506.0 89686.0 81276.0 80189.0 79023.0 91841.0 75984.0 78134.0 84130.0 False True 79232.78072029667 85308.01611047318 82312.36327797158 87253.308168788 75472.44067763982 75643.37050161023 96596.0775985357 79514.49403322958 69333.72613250423 98671.75840382159 0.802993500896483 0.8645636551985191 0.8342038756530724 0.8842784356968413 0.7648839130723017 0.7666162205403704 0.9789637801244911 0.8058485560560352 0.7026704221561629 1.0 16.59034959856725 IFYPEIEEVQALDDTERGS(ph)GGFGSTGKN ddPTM_PC-9_AZD4547_30min_R2 1 IFYPEIEEVQALDDTERGSGGFGSTGKN 28 2 P33316-2;A0A0C4DGL3;H0YNW5;P33316 P33316-2;H0YNW5;P33316 DUT Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial 1 IFYPEIEEVQALDDT(0.193)ERGS(0.803)GGFGS(0.003)T(0.001)GKN 83.24700000000001 7.836900000000001e-06 10035000.0 17255.0 13602.0 22519.0 33226.0 28501.0 24854.0 16579.0 23424.0 19432.0 19163.0 True False 22741.731073704006 17998.58049839264 22220.38334634679 25566.2590365828 24544.12811307064 23299.875451005668 18054.498882221294 19804.359029971612 20459.135848785732 18492.109202763255 1.2298073099365936 0.9733113892547818 1.2016143265596995 1.3825496462438402 1.3272757501022674 1.259990150151395 0.9763352943818562 1.0709626907790633 1.1063711350854746 1.0 14.174622166910385 -7.254575890625712 24.9330771425907 1.0443308364062316 1.2276544057522445 0.43861886385485227 0.10558528327690453 595.8902179604906 2164701.8937864825 0.04622377728707888 0.035020085942760286 5.56447389572445e-08 7.254575890625712 0.1833235693460129 IFYPETTDIYDR ddPTM_PC-9_Lapatinib_30min_R1 2 IFYPETTDIYDR 12 0 P46940;A0A0J9YXZ5 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 0 ; 123.96 0.0015505999999999999 5456200.0 18154.199999999997 17502.4 19583.3 15002.699999999999 20357.4 19414.5 19573.6 20869.8 16928.3 16897.6 False True 17895.317778927452 17461.874268144253 17973.236667724068 16106.04860554007 19160.017756188307 18584.187092409946 20587.025233639655 21839.487096950645 15021.656591098255 19818.327645363293 0.9029681060457314 0.8810972641392193 0.9068997641649696 0.8126845460297075 0.9667827729486042 0.9377273110507844 1.0387872075803635 1.1019843595158354 0.7579679203967914 1.0 14.274547606476728 -6.387422742468487 7.559787415971861 0.9752727541369298 0.8786608066181405 0.20732175853243429 0.08665699779571669 0.41893330033736964 23.904656396153783 0.026475233234339268 0.030010351078676188 4.0980500437805634e-07 6.387422742468487 -0.09661194751878932 IFYYFSNSPS(ph)KR ddPTM_PC-9_AZD4547_30min_R2 1 IFYYFSNSPSKR 12 1 Q08999;Q08999-2 Q08999 RBL2 Retinoblastoma-like protein 2 1 IFYYFS(0.006)NS(0.089)PS(0.904)KR 58.268 0.031617 4142900.0 12733.0 9331.9 14892.0 16855.0 15237.0 14363.0 14776.0 15500.0 10395.0 12714.0 True False 16781.82913714711 12348.25417974932 14694.522349740055 12969.340157154116 13121.605559764825 13464.8793394542 16091.03537509512 13104.831154566251 10944.458478186894 12268.886729840417 1.3678363413634183 1.006469001764917 1.197706252678982 1.0570918488969383 1.0695025431973728 1.0974817549423526 1.3115318226843242 1.0681353119588795 0.8920498427593887 1.0 13.582716725355091 -1.5228787762106129 0.10398547800179622 0.9271900554386118 1.7352777398444896 0.23033270050131738 0.1213582085141192 226.05661349759689 1.6624359389636238 1.3952290266767735 26.102368630074775 0.029999997863412353 1.5228787762106129 0.8080876844058779 IFYYFSNSPS(ph)KR ddPTM_PC-9_Lapatinib_30min_R1 1 IFYYFSNSPSKR 12 1 Q08999;Q08999-2 Q08999 RBL2 Retinoblastoma-like protein 2 1 IFYYFS(0.071)NS(0.321)PS(0.608)KR 52.891000000000005 0.042763999999999996 2202200.0 13521.0 11768.0 10244.0 10318.0 11275.0 9255.7 10955.0 11939.0 8765.5 8992.5 True False 13328.188060552284 11740.751919023758 9401.777862983532 11076.820139838992 10611.826667502884 8859.855287090517 11522.19629677333 12493.729525462337 7778.237085192943 10546.841643246942 1.263713679543697 1.1132007397248889 0.8914306463493187 1.0502499719365173 1.0061615625278257 0.8400481951640386 1.0924783633355204 1.1845943978368132 0.7374944413025567 1.0 13.364523413760736 -4.952124284400446 3.4813668227118275 0.9850775678262429 1.2593334936980682 0.3567770733657085 0.12179316900579822 0.2743753344273139 6.479618607415459 0.030464274881384763 0.15797843314409798 1.1165436747143746e-05 4.952124284400446 0.27425592587182535 IGAEVYHNLK ddPTM_PC-9_AZD4547_30min_R2 2 IGAEVYHNLK 10 0 P06733;A0A2R8Y6G6;P06733-2;K7EM90 P06733 ENO1 Alpha-enolase;Enolase 0 ; 160.75 0.00045809 86139000.0 337830.0 341700.0 446920.0 589500.0 567220.0 446590.0 409280.0 505490.0 407470.0 447740.0 False True 445252.9126994746 452147.8426923078 440993.5487876595 453599.8826842102 488471.2939298941 418664.65670172294 445705.12711958075 427378.1355046249 429008.0323335082 432064.7588814495 1.0305235582095778 1.0464816521089346 1.0206653973106377 1.0498423520087865 1.1305511127416932 0.9689858941182395 1.0315701939529716 0.989152960799308 0.9929253046329103 1.0 18.720888037555227 -6.8104110713006145 24.999999027809185 0.9980391500136003 1.0528443985215443 0.4722228778466878 0.03114318564492089 112.69691886555057 57530.75558354502 0.011151320967925184 0.009834559607582073 1.5473513162917283e-07 6.8104110713006145 0.05480524850794399 IGAEVYHNLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IGAEVYHNLK 10 0 P06733;A0A2R8Y6G6;P06733-2;K7EM90 P06733 ENO1 Alpha-enolase;Enolase 0 ; 79.48899999999999 0.015909 87275000.0 365270.0 378790.0 401650.0 463730.0 531630.0 421550.0 460100.0 437330.0 408190.0 396590.0 False True 427102.996588649 416393.76786410017 411226.8592661069 437748.7115329439 427460.9178378882 399443.1759036372 416515.99716446496 425850.5508894371 414159.0065303895 468488.62759528746 0.9116613967364215 0.888802296016051 0.8777734080267853 0.9343849257982441 0.9124253880654669 0.8526208585978816 0.8890631973339596 0.9089880219191061 0.8840321453612069 1.0 18.83765450180683 -11.661255492219093 2.367755412241152 1.2224527861967258 0.895391558316934 0.6804735591211142 0.02147659324697012 2537092.4471215145 682895.3413047383 3032104.817062049 0.005954350890215637 2.1814462056769312e-12 11.661255492219093 -0.32706122787979186 IGAEVYHNLK ddPTM_PC-9_Lapatinib_30min_R1 2 IGAEVYHNLK 10 0 P06733;A0A2R8Y6G6;P06733-2;K7EM90 P06733 ENO1 Alpha-enolase;Enolase 0 ; 157.78 0.00033214 155173000.0 920270.0 862380.0 948310.0 899080.0 971350.0 901490.0 822480.0 827310.0 919550.0 803430.0 False True 907146.7810431514 860383.2120944677 870343.6123824591 965201.3424429577 914217.1027475768 862935.3741758291 865063.9899744528 865749.8428436419 815980.5957092214 942301.8049968171 0.9626923945520994 0.9130654398962696 0.9236357266506551 1.0243017017740064 0.9701956399740366 0.9157738737205793 0.9180328270488399 0.9187606754574413 0.8659440015738669 1.0 19.845829681659957 -6.770325134225782 24.595117468418536 0.9182704672808408 0.9579264212827641 0.1453873380248829 0.04146274473438494 290.5487024887131 804211.7441941284 0.014748829688486845 0.013200595570047905 1.6969727394667695e-07 6.770325134225782 0.03965595400192323 IGDEDVGR ddPTM_PC-9_AZD4547_30min_R2 3 IGDEDVGR 8 0 P23284 P23284 PPIB Peptidyl-prolyl cis-trans isomerase B 0 ;; 122.18 0.0021736999999999998 3498300.0 210681.0 231308.0 333361.0 437346.0 352774.0 334575.0 292763.0 374490.0 325938.0 357879.0 False True 277673.17556296947 306073.78752552613 328940.4153257917 336522.6366283435 303797.419422489 313653.9723593876 318818.33984291926 316621.1754240973 343166.4172643852 345349.7651398904 0.80403464426997 0.8862718855521595 0.9524848386462582 0.9744400332573808 0.8796803996650472 0.9082211833337607 0.9231752038799733 0.916813061378061 0.9936778648897566 1.0 18.397698716961038 -4.874528280111471 2.665508023118328 0.9371653769996404 0.7912316168147269 0.5744811360249986 0.036939333593911994 0.28470020333041485 3.1403038984407874 0.009675155558495466 0.0854633520607028 1.3349706569629933e-05 4.874528280111471 -0.14593376018491355 IGDEDVGR ddPTM_PC-9_Lapatinib_30min_R1 1 IGDEDVGR 8 0 P23284 P23284 PPIB Peptidyl-prolyl cis-trans isomerase B 0 98.62899999999999 0.021449 0.0 35255.0 40070.0 47402.0 44586.0 41401.0 41602.0 46290.0 38761.0 45614.0 30268.0 False True 34752.25723502483 39977.22037689346 43504.79053701146 47865.003174535894 38965.87457749774 39822.77943899861 48686.66970129049 40561.977563987384 40476.47098328574 35499.78347042514 0.978942794509632 1.1261257525753212 1.225494532192155 1.3483181725435653 1.0976369647426216 1.1217752770851392 1.371463849683797 1.142597886485126 1.1401892357176395 1.0 15.115522604530247 -4.836382397323645 2.9759117071111043 1.193201557484532 0.9570295924012441 0.2386254967350191 0.10680307089397732 0.4539279521048335 6.265512793393706 0.02697372774449156 0.24298489494938338 1.457530336183596e-05 4.836382397323645 -0.23617196508328797 IGDSS(ph)QGDNNLQK ddPTM_PC-9_AZD4547_30min_R2 2 IGDSSQGDNNLQK 13 0 A0A0D9SG77;A0A1B0GVL3;Q05086-2;Q05086-3;Q05086 A0A0D9SG77 UBE3A Ubiquitin-protein ligase E3A 1 IGDS(0.125)S(0.875)QGDNNLQK;IGDS(0.262)S(0.738)QGDNNLQK 171.11 7.2232e-05 9006800.0 40623.0 40664.0 39948.0 57116.0 50019.0 48084.0 43002.0 47372.0 41188.0 47945.0 True False 53540.26898910912 53807.842772139236 39418.26341844048 43948.78863340345 43074.725240787324 45077.29987873813 46829.094694087726 40051.745900265305 43365.11359303147 46266.460143322205 1.1572155903705283 1.1629989112081554 0.8519835599337472 0.9499060117688024 0.9310140673687232 0.974297574076332 1.012160743420236 0.8656756055292488 0.9372905006930924 1.0 15.49767910177153 -5.247424614735103 24.958678024887192 0.9392870793587217 1.1601073000602615 0.7671387307588483 0.04844051831290558 347.321301045688 618536.5830839192 0.012284070944600073 0.032141147505631185 5.656859408915419e-06 5.247424614735103 0.22082022070153984 IGDSS(ph)QGDNNLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IGDSSQGDNNLQK 13 0 A0A0D9SG77;A0A1B0GVL3;Q05086-2;Q05086-3;Q05086 A0A0D9SG77 UBE3A Ubiquitin-protein ligase E3A 1 IGDS(0.254)S(0.746)QGDNNLQK;IGDS(0.053)S(0.947)QGDNNLQK 104.7 0.0030716999999999997 0.0 35600.0 39322.4 27712.6 33541.0 35452.0 33351.0 36056.0 33441.0 32395.3 24910.2 True False 41626.3768679495 43226.06799931181 28373.37348462074 31661.80651138917 28505.435094311408 31602.014848919975 32640.51465716566 32563.20918366833 32869.0199766136 29426.222070965287 1.4146014655759036 1.4689642419970306 0.9642207353765815 1.0759725266475755 0.968708624082518 1.0739406089136239 1.1092322547708868 1.1066051600214861 1.1169976185643384 1.0 14.84481471118056 -5.255514173768562 24.999978935764744 1.0564818464561194 1.441782900813735 0.8883884872919445 0.0552502805397897 142.364165401137 600667.137615383 0.014640900478000728 0.03665444183946338 5.552464956280962e-06 5.255514173768562 0.38530105435761564 IGDSS(ph)QGDNNLQK ddPTM_PC-9_Lapatinib_30min_R1 2 IGDSSQGDNNLQK 13 0 A0A0D9SG77;A0A1B0GVL3;Q05086-2;Q05086-3;Q05086 A0A0D9SG77 UBE3A Ubiquitin-protein ligase E3A 1 IGDS(0.014)S(0.986)QGDNNLQK;IGDS(0.129)S(0.871)QGDNNLQK 204.17 9.918799999999999e-10 14529700.0 55563.0 49341.0 58585.0 49940.0 51235.0 49826.0 46460.0 48815.0 59946.0 40197.0 True False 54770.66143099371 49226.75394600198 53768.36744463982 53612.75419495629 48221.458031885595 47695.05813007896 48865.471469474076 51083.123107918895 53194.250220635 47144.99789086427 1.1617491543383254 1.0441564566395094 1.140489338213737 1.1371886009850758 1.022832966150793 1.011667414653152 1.0364932369409054 1.0835321962718287 1.1283116470547758 1.0 15.524817087865118 -6.258458389653755 24.997415410519622 1.0490102611432317 1.1168140329985363 0.3887255876095781 0.04515841872750852 316.8399908371685 2656885.245315895 0.014054023180619967 0.017383800555214397 5.514950393419081e-07 6.258458389653755 0.06780377185530462 IGEEQSPEDAEDGPPELLFIHGGHTAK ddPTM_PC-9_Lapatinib_30min_R1 1 IGEEQSPEDAEDGPPELLFIHGGHTAK 27 0 Q09028-3;Q09028;Q09028-4;Q09028-2;H0YF10;H0YEU5;H0YCT5;H0YDK2 Q09028-3 RBBP4 Histone-binding protein RBBP4 0 110.25 1.1217e-10 2645400.0 21208.0 19971.0 18958.0 18540.0 18092.0 18107.0 16858.0 14512.0 17021.0 18380.0 False True 20905.570030929128 19924.75837651458 17399.346419996273 19903.49344762694 17027.86413024054 17332.605819478595 17730.8247531725 15186.280498660637 15103.91574092398 21556.95851018946 0.9697829135333523 0.9242843032377049 0.807133641407345 0.9232978501219936 0.7899010485264828 0.8040376294868261 0.8225105014138039 0.7044723165135957 0.7006515197301475 1.0 14.39586602091439 -4.848123174806404 0.602814144699819 0.787347965355334 1.077728806864605 0.2607571514983703 0.08565566405781906 4.190935104031123 1.2207942633148683 0.04309454657347345 0.8402689224735468 1.4186551049929975e-05 4.848123174806404 0.2903808415092709 IGEGT(ph)Y(ph)GVVYK ddPTM_PC-9_AZD4547_30min_R2 1 IGEGTYGVVYK 11 0 E5RIU6;A0A087WZZ9;P06493;K7ELV5;E7ESI2;A0A024QZP7;P24941-2;G3V317;P06493-2;G3V5T9;P24941;Q00526 E5RIU6;G3V5T9 CDK1;CDK3;CDK2;CDC2 Cyclin-dependent kinase 1;Cyclin-dependent kinase 2;Cyclin-dependent kinase 3 2 IGEGT(1)Y(1)GVVYK 143.42 0.014487 7114600.0 34953.0 36687.0 54495.0 49584.0 46155.0 39220.0 44259.0 40553.0 38491.0 37799.0 True False 46067.3269324356 48545.355296613045 53772.36069359953 38153.17486516346 39747.174943292324 36767.56719998563 48197.96525895602 34286.465665233896 40525.5556790661 36475.66851512019 1.2629604557717538 1.3308969313746677 1.4741980855350019 1.045989735578058 1.0896901019597764 1.00800255887687 1.3213730473226724 0.9399818306557204 1.1110298269726604 1.0 15.154646799217232 -5.772894354762335 24.999924244937382 1.079468665719132 1.3535063395144564 0.59256356838591 0.10718895434931491 143.8417558280796 313927.64857957634 0.02946599668152846 0.044134937808654816 1.6869633413741228e-06 5.772894354762335 0.2740376737953245 IGEGT(ph)Y(ph)GVVYK ddPTM_PC-9_Lapatinib_30min_R1 2 IGEGTYGVVYK 11 0 E5RIU6;A0A087WZZ9;P06493;K7ELV5;E7ESI2;A0A024QZP7;P24941-2;G3V317;P06493-2;G3V5T9;P24941;Q00526 E5RIU6;G3V5T9 CDK1;CDK3;CDK2;CDC2 Cyclin-dependent kinase 1;Cyclin-dependent kinase 2;Cyclin-dependent kinase 3 2 IGEGT(1)Y(1)GVVYK;IGEGT(1)Y(1)GVVYK 128.36 0.030139 12544500.0 90147.0 77961.0 58816.0 72079.0 70018.0 62057.0 64308.0 69996.0 70825.0 54588.0 True False 88861.487249065 77780.48609440938 53980.375516325636 77379.93010849513 65899.67890068442 59402.966771932515 67637.55357853942 73248.26969296092 62847.94267968631 64023.463066062155 1.387951900655138 1.2148747095131693 0.8431342656461174 1.208618315892272 1.0293051288507513 0.9278312032361946 1.0564494692945317 1.144084780565216 0.9816392252139986 1.0 15.966313094750804 -5.010508485624628 5.384318089467805 1.0325810360891232 1.3551845326877117 0.5865759853298054 0.09796363744180615 0.10177543027601221 10.076914684612452 0.024203291432464004 0.08221774474529688 9.760937104730668e-06 5.010508485624628 0.32260349659858845 IGEGT(ph)YGVVY(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IGEGTYGVVYK 11 0 E5RIU6;A0A087WZZ9;P06493;K7ELV5;E7ESI2;A0A024QZP7;P24941-2;G3V317;P06493-2;G3V5T9;P24941;Q00526 E5RIU6;G3V5T9 CDK1;CDK3;CDK2;CDC2 Cyclin-dependent kinase 1;Cyclin-dependent kinase 2;Cyclin-dependent kinase 3 2 IGEGT(1)Y(0.192)GVVY(0.808)K 100.09 0.044973 0.0 18764.0 16304.0 17667.0 19042.0 22990.0 16684.0 21490.0 21797.0 19483.0 13493.0 True False 21940.37459410687 17922.553370617763 18088.248282470606 17975.138474996947 18485.274535095872 15809.061669496577 19454.311625873375 21224.851845830526 19767.902016785243 15939.17408947077 1.3765063654459 1.124434256757205 1.134829708298342 1.1277333677452657 1.1597385429968436 0.9918369409077386 1.2205344842004495 1.331615535829514 1.2402086774272505 1.0 13.960289255559466 -11.228855930677925 12.41652582570113 0.9999591602462001 1.1827363669282613 0.22488983583706734 0.10494502754910283 0.0001242121539497091 2.9413761714332226e-06 0.10638101762657624 0.02579545665922311 5.903969011600689e-12 11.228855930677925 0.1827772066820612 IGEGT(ph)YGVVYK ddPTM_PC-9_AZD4547_30min_R2 5 IGEGTYGVVYK 11 0 E5RIU6;A0A087WZZ9;P06493;K7ELV5;E7ESI2;A0A024QZP7;P24941-2;G3V317;P06493-2;G3V5T9;P24941;Q00526 E5RIU6;G3V5T9 CDK1;CDK3;CDK2;CDC2 Cyclin-dependent kinase 1;Cyclin-dependent kinase 2;Cyclin-dependent kinase 3 1 IGEGT(0.564)Y(0.436)GVVYK;IGEGT(0.999)Y(0.001)GVVYK;IGEGT(0.816)Y(0.184)GVVYK;IGEGT(1)YGVVYK;IGEGT(0.995)Y(0.005)GVVYK 140.45 0.00014449 935096000.0 439933.0 314248.0 548053.0 492934.0 450380.0 298416.0 496591.0 247383.7 324078.0 309623.0 True False 579822.5428251419 415822.52054542635 540785.4591285309 379295.6820543818 387852.5111246886 279756.0003455097 540786.6369757617 209156.23347689497 341208.10146165016 298783.19301190646 1.9406129808715047 1.3917199168858734 1.809959434722892 1.2694679316827133 1.2981068553920727 0.9363177276653625 1.8099633768697674 0.7000267698074976 1.1419922855167195 1.0 18.188739471157213 -1.522878745280387 0.2237369713553046 0.9498402356652855 5.893331980305088 0.43204613684867343 0.2955682336659638 48.25772106359071 0.6226224682972951 0.43440686617906776 86.59268542819572 0.029999999999996592 1.522878745280387 4.943491744639802 IGEGT(ph)YGVVYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 IGEGTYGVVYK 11 0 E5RIU6;A0A087WZZ9;P06493;K7ELV5;E7ESI2;A0A024QZP7;P24941-2;G3V317;P06493-2;G3V5T9;P24941;Q00526 E5RIU6;G3V5T9 CDK1;CDK3;CDK2;CDC2 Cyclin-dependent kinase 1;Cyclin-dependent kinase 2;Cyclin-dependent kinase 3 1 IGEGT(0.823)Y(0.177)GVVYK;IGEGT(0.999)Y(0.001)GVVYK;IGEGT(1)YGVVYK;IGEGT(0.999)Y(0.001)GVVYK;IGEGT(1)YGVVYK 134.18 0.00014449 114274800.0 391159.0 398278.0 331139.0 560626.0 382845.0 451624.0 407599.0 739016.0 416833.0 250779.0 True False 457374.4929575918 437816.4077123963 339034.6096116515 529215.9427940162 307829.2705258286 427940.04240138625 368988.2719587881 719617.6130521761 422928.39405443886 296243.2475345285 1.5439153356711792 1.4778949777120804 1.1444467086870411 1.786423647453209 1.0391098298027863 1.444556275840542 1.2455584221064173 2.4291443570145894 1.4276389337959328 1.0 18.176422744533873 IGEGT(ph)YGVVYK ddPTM_PC-9_Lapatinib_30min_R1 2 IGEGTYGVVYK 11 0 E5RIU6;A0A087WZZ9;P06493;K7ELV5;E7ESI2;A0A024QZP7;P24941-2;G3V317;P06493-2;G3V5T9;P24941;Q00526 E5RIU6;G3V5T9 CDK1;CDK3;CDK2;CDC2 Cyclin-dependent kinase 1;Cyclin-dependent kinase 2;Cyclin-dependent kinase 3 1 IGEGT(0.998)Y(0.002)GVVY(0.001)K;IGEGT(1)YGVVYK 113.77 0.0037265999999999996 72361000.0 240604.0 212592.0 222747.0 268260.0 232087.0 188622.0 167563.0 185906.0 182663.0 129070.0 True False 237172.94283863012 212099.75628561302 204433.6014882854 287988.7352891263 218436.09896059797 180555.0767593576 176238.5922479442 194543.8714432197 162089.5694133363 151379.57752503586 1.566743326386978 1.401112090239088 1.3504701547636122 1.9024279232216603 1.4429694053312574 1.1927307481717377 1.164216436122614 1.2851394793399071 1.070749252068227 1.0 17.207811060271 -6.712599813148557 3.953789546882539 1.1582314329126544 1.543956967690989 0.6196931074294996 0.15427410387664392 0.16289559175554424 5.269958154993399 0.0549511069074382 0.05305600519984676 1.938207129971619e-07 6.712599813148557 0.3857255347783346 IGEGTY(ph)GVVYK ddPTM_PC-9_AZD4547_30min_R2 5 IGEGTYGVVYK 11 0 E5RIU6;A0A087WZZ9;P06493;K7ELV5;E7ESI2;A0A024QZP7;P24941-2;G3V317;P06493-2;G3V5T9;P24941;Q00526 E5RIU6;G3V5T9 CDK1;CDK3;CDK2;CDC2 Cyclin-dependent kinase 1;Cyclin-dependent kinase 2;Cyclin-dependent kinase 3 1 IGEGT(0.123)Y(0.877)GVVYK;IGEGT(0.011)Y(0.989)GVVYK;IGEGT(0.223)Y(0.777)GVVYK;IGEGT(0.019)Y(0.981)GVVYK;IGEGT(0.472)Y(0.527)GVVY(0.002)K 172.59 0.00046166 1678960800.0 612592.0 552578.0 758196.0 963031.0 787462.0 801761.0 739625.0 944029.0 679675.0 834160.0 True False 807383.5132948405 731188.0322482587 748141.8256435349 741019.0816306309 678136.4938835409 751626.7579252325 805450.1921565175 798151.0096783225 715601.2329159862 804956.3122985419 1.0030153201598826 0.9083574115474182 0.9294191674914953 0.9205705580650221 0.8424513026640306 0.9337485108713198 1.0006135486490757 0.9915457491093064 0.8889938770373718 1.0 19.618550959849678 -7.0135841919729724 24.58658446789996 0.9692405316641042 0.9172994167074849 0.19842858838217858 0.04696218037183398 848.1576152986378 1535113.827097806 0.017560386270121672 0.014233693186139483 9.692053617285066e-08 7.0135841919729724 -0.05194111495661924 IGEGTY(ph)GVVYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 IGEGTYGVVYK 11 0 E5RIU6;A0A087WZZ9;P06493;K7ELV5;E7ESI2;A0A024QZP7;P24941-2;G3V317;P06493-2;G3V5T9;P24941;Q00526 E5RIU6;G3V5T9 CDK1;CDK3;CDK2;CDC2 Cyclin-dependent kinase 1;Cyclin-dependent kinase 2;Cyclin-dependent kinase 3 1 IGEGT(0.042)Y(0.957)GVVY(0.001)K;IGEGT(0.081)Y(0.891)GVVY(0.028)K;IGEGT(0.013)Y(0.987)GVVYK;IGEGT(0.02)Y(0.973)GVVY(0.007)K;IGEGT(0.305)Y(0.695)GVVYK;IGEGT(0.032)Y(0.968)GVVYK;IGEGT(0.154)Y(0.829)GVVY(0.017)K 159.79 0.00034608 2321423000.0 374485.0 382021.0 398008.0 464038.0 457685.0 403966.0 509257.0 436658.0 388272.0 355097.0 True False 437877.9140841022 419945.5201911663 407498.0201737448 438039.4552914943 368004.90976926323 382781.3118185 461016.4902586044 425196.1901773943 393949.7434615429 419473.27515369514 1.043875593561148 1.0011258048258216 0.9714516855083019 1.0442606984461562 0.8773023969987745 0.9125284839141392 1.099036619412018 1.0136430980533915 0.9391533782866133 1.0 18.67821937322727 -10.625819948314675 14.858056820109555 0.9999999781972948 0.9890143309538049 0.0026330444051519963 0.06328055726921604 0.0 0.0 0.06333179501698476 0.015360216489117319 2.3669007740657607e-11 10.625819948314675 -0.010985647243489938 IGEGTY(ph)GVVYK ddPTM_PC-9_Lapatinib_30min_R1 6 IGEGTYGVVYK 11 0 E5RIU6;A0A087WZZ9;P06493;K7ELV5;E7ESI2;A0A024QZP7;P24941-2;G3V317;P06493-2;G3V5T9;P24941;Q00526 E5RIU6;G3V5T9 CDK1;CDK3;CDK2;CDC2 Cyclin-dependent kinase 1;Cyclin-dependent kinase 2;Cyclin-dependent kinase 3 1 IGEGT(0.005)Y(0.995)GVVYK;IGEGT(0.477)Y(0.523)GVVYK;IGEGT(0.011)Y(0.989)GVVYK;IGEGT(0.098)Y(0.902)GVVYK;IGEGT(0.041)Y(0.941)GVVY(0.018)K;IGEGT(0.036)Y(0.949)GVVY(0.015)K 172.59 0.00047329 2529602800.0 802846.0 650929.0 752077.0 742720.0 787622.0 682642.0 621335.0 632676.0 747568.0 544894.0 True False 791397.2688160758 649421.8138934573 690244.1321611749 797342.106441289 741295.6224844316 653446.9929762253 653504.6860844966 662072.4366572908 663369.0195999681 639078.2018743834 1.2383418281126604 1.0161852054861777 1.0800620802535972 1.2476440349596116 1.1599450901474182 1.0224836194689462 1.0225738949752958 1.035980314639846 1.0380091476353615 1.0 19.285632954205774 -6.7655221498415905 24.96498189944392 1.025980926082193 1.142801452701316 0.4832547959682738 0.06428472266365919 102.92386279460779 629346.127490384 0.023229641178153036 0.021230711869094754 1.7158441965836848e-07 6.7655221498415905 0.1168205266191229 IGEGTYGVVYK ddPTM_PC-9_AZD4547_30min_R2 2 IGEGTYGVVYK 11 0 E5RIU6;A0A087WZZ9;P06493;K7ELV5;E7ESI2;A0A024QZP7;P24941-2;G3V317;P06493-2;G3V5T9;P24941;Q00526 E5RIU6;G3V5T9 CDK1;CDK3;CDK2;CDC2 Cyclin-dependent kinase 1;Cyclin-dependent kinase 2;Cyclin-dependent kinase 3 0 ; 147.2 0.0011527999999999998 8897700.0 22842.0 21780.0 28617.0 40133.0 33796.0 29849.0 28422.0 32702.0 32063.0 32851.0 False True 30105.28085688479 28819.9590688863 28237.519881984368 30880.956898669017 29104.008761423647 27982.53731138122 30951.50293929029 27648.657317201654 33757.78472208817 31700.89648906618 0.9496665454640462 0.9091212634578478 0.8907483071251202 0.9741351292484752 0.9180815681809436 0.8827049203808024 0.976360493463194 0.8721727263056372 1.0648842291804403 1.0 14.952236019347632 -8.267081337006513 24.997681701379314 1.0324421227966336 0.9223374844332205 0.5885924266654219 0.03705569649994993 322.3483055540207 1428197.7549006885 0.03032350778674173 0.00869058840755385 5.4065305705052856e-09 8.267081337006513 -0.11010463836341311 IGEGTYGVVYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IGEGTYGVVYK 11 0 E5RIU6;A0A087WZZ9;P06493;K7ELV5;E7ESI2;A0A024QZP7;P24941-2;G3V317;P06493-2;G3V5T9;P24941;Q00526 E5RIU6;G3V5T9 CDK1;CDK3;CDK2;CDC2 Cyclin-dependent kinase 1;Cyclin-dependent kinase 2;Cyclin-dependent kinase 3 0 ; 129.85 0.0010997 9141300.0 30018.0 35520.0 38546.0 34857.0 44649.0 40694.0 36626.0 43664.0 40398.0 26695.0 False True 35099.454517474966 39046.19085649798 39465.082826519036 32904.07529791874 35900.34896552832 38559.93500230727 33156.52013072303 42517.86626583219 40988.744324492654 31534.592182496264 1.1130460896512697 1.238201865130545 1.2514854353634135 1.0434279634091044 1.138443419777451 1.2227821047804932 1.0514332939154685 1.3482928848349705 1.2998025814725473 1.0 14.944647655390671 -7.761390706002011 24.999999999999318 1.2430357664796685 1.1565692912926762 0.05102382354407753 0.10931715239155639 2.908539014456212 1496230.7424896273 0.05347706167063838 0.02832835136246092 1.7322449104564678e-08 7.761390706002011 -0.08646647518699235 IGEGTYGVVYK ddPTM_PC-9_Lapatinib_30min_R1 4 IGEGTYGVVYK 11 0 E5RIU6;A0A087WZZ9;P06493;K7ELV5;E7ESI2;A0A024QZP7;P24941-2;G3V317;P06493-2;G3V5T9;P24941;Q00526 E5RIU6;G3V5T9 CDK1;CDK3;CDK2;CDC2 Cyclin-dependent kinase 1;Cyclin-dependent kinase 2;Cyclin-dependent kinase 3 0 ;;; 152.97 0.00038438 24372900.0 119457.0 91698.0 104076.0 105889.0 99860.0 95547.0 85409.0 87110.0 109750.0 78782.0 False True 117753.52127426934 91485.6789149082 95519.27302497787 113676.430295349 93986.43113231391 91460.67754093547 89831.06011055355 91157.44861068972 97388.79928126482 92399.36372958375 1.2743975339363498 0.9901115681126382 1.0337654846252498 1.2302728688482614 1.017176172417971 0.9898409886090186 0.972204314885256 0.9865592676316622 1.053998592092941 1.0 16.495595296695818 -6.492310004076202 23.703343963085363 0.9985327672717635 1.1160605705636684 0.37603831417477973 0.08046203144849719 426.89088281132973 331015.8977555308 0.024793453610022616 0.02806786402034764 3.218770378120221e-07 6.492310004076202 0.11752780329190482 IGEHMEEHGIK ddPTM_PC-9_Lapatinib_30min_R1 3 IGEHMEEHGIK 11 0 Q16881;Q16881-5;A0A182DWI3;Q16881-2;F8W809;Q16881-3;Q16881-6;Q16881-4;A0A087WSW9;E9PIR7;A0A087WSY9;Q16881-7;E2QRB9 Q16881 TXNRD1 Thioredoxin reductase 1, cytoplasmic 0 ;; 123.11 0.00025356 25685600.0 214875.0 214632.0 241331.0 202522.0 239006.0 211881.0 213599.0 208463.0 238337.0 207792.0 False True 211810.8430967511 214135.03279095102 221489.69674459964 217416.14347358726 224948.1369838752 202819.34354873502 224658.1110720662 218148.95201159723 211492.97726012563 243708.5703345643 0.8691152830857616 0.8786520412350924 0.908830150866412 0.8921152964588702 0.9230210356372175 0.832220808937099 0.9218309834719988 0.8951222015381785 0.8678109964281807 1.0 17.894797460671505 -10.691976763144577 4.357158671732528 1.0000266609974733 0.8887632032657764 0.6238087726385735 0.02616437775833851 6.509101269392533e-06 1.2412280736203754e-06 0.024334588325961314 0.005900590783666259 2.0324657547757584e-11 10.691976763144577 -0.11126345773169688 IGEHTPSALAIMENANVLAR ddPTM_PC-9_AZD4547_30min_R2 3 IGEHTPSALAIMENANVLAR 20 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BPS8;H3BR04;H3BU78 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ;; 164.97 4.2527999999999995e-08 23485500.0 113217.0 118617.0 127072.0 175598.0 160449.0 154178.0 126070.0 154252.0 125096.0 147707.0 False True 149217.65094010707 156957.6255681401 125386.94225263005 135116.59406205578 138173.42590133916 144537.22528708278 137289.9857700491 130415.89775833265 131708.31917145438 142535.82288851152 1.0468782367561165 1.1011801972821176 0.8796872232653052 0.9479483215089101 0.969394381715644 1.0140413992637958 0.9631963599595197 0.9149692695873456 0.9240366141112035 1.0 17.12096502535364 -5.248046985749443 24.999483331874313 0.9517632290840017 1.0740292299281253 0.60790566583261 0.03931075343138452 537.8298159734467 1003958.7441162548 0.010399281437195975 0.02716814806003436 5.648758583292983e-06 5.248046985749443 0.12226600084412365 IGEHTPSALAIMENANVLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IGEHTPSALAIMENANVLAR 20 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BPS8;H3BR04;H3BU78 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ;; 109.28 5.8996e-05 24900000.0 69801.8 67870.0 71423.1 93868.1 102264.9 99981.5 89326.8 86723.4 85481.0 74288.2 False True 81617.8660916079 74607.68506279618 73126.09757761518 88608.97468148645 82226.82695972727 94738.29413262854 80865.11883397249 84447.00264103776 86730.99791083593 87756.06259493242 0.9300538752330146 0.8501712913804373 0.8332882699529631 1.0097191243696853 0.9369931207975091 1.079564093137644 0.9214761515364769 0.962292520242519 0.9883191582007499 1.0 16.42121117645968 -5.764249489967322 24.99993771020549 0.9831424393297048 0.869071152157731 0.5541235000747596 0.04694482746399309 52.412250100035656 466288.2214546916 0.012827112979058407 0.020025592121316285 1.7208796939786585e-06 5.764249489967322 -0.11407128717197379 IGEHTPSALAIMENANVLAR ddPTM_PC-9_Lapatinib_30min_R1 4 IGEHTPSALAIMENANVLAR 20 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BPS8;H3BR04;H3BU78 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ;;; 118.66 1.2057999999999999e-05 18617800.0 75809.0 60439.0 73081.0 61942.0 68231.0 72942.0 60666.0 57500.0 82230.0 64219.0 False True 74727.94975833186 60299.05720886109 67072.56228081787 66497.42131245472 64217.78672730721 69822.44069610695 63806.988638982235 60171.6599140702 72968.39147971197 75319.16858356127 0.9921504865713766 0.8005804942199218 0.8905111878180868 0.8828751374051687 0.8526088104127455 0.9270208634690903 0.847154712922686 0.7988890616512052 0.968789125689282 1.0 16.200729454289252 -8.445441818841118 6.490227089366755 0.9996974209821836 0.8727413433754951 0.4046147051500294 0.05419326890701825 0.19310315459801605 12.38167098857058 0.04918463507066499 0.012737095761037999 3.5855697988686915e-09 8.445441818841118 -0.12695607760668848 IGELGAPEVWGLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 IGELGAPEVWGLSPK 15 0 A0A494C050;Q8N5F7 A0A494C050 NKAP NF-kappa-B-activating protein 1 IGELGAPEVWGLS(1)PK;IGELGAPEVWGLS(1)PK;IGELGAPEVWGLS(1)PK 156.11 2.4628e-06 1233400000.0 165237.3 157856.3 141690.6 141221.2 161184.9 156205.9 174166.1 163394.3 147771.8 150392.0 True False 217779.32425064946 208880.26192680633 139811.69006500652 108664.83418579017 138807.158888898 146438.3203795061 189666.54549555754 138145.46536248666 155582.71566589113 145126.82185576233 1.5006138869842716 1.439294675207639 0.963375951303899 0.7487577609450391 0.956454204081274 1.0090369134180257 1.306902081023052 0.9518947882686065 1.0720465981162368 1.0 17.146954652575204 -5.24052683710577 6.980108723998828 0.9997427250907136 1.4738393908648826 0.6744562345180289 0.1303321782766677 0.11096425818475351 24.640700874720533 0.03654570632457545 0.09295963413265577 5.74742301708722e-06 5.24052683710577 0.474096665774169 IGELGAPEVWGLS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 IGELGAPEVWGLSPK 15 0 A0A494C050;Q8N5F7 A0A494C050 NKAP NF-kappa-B-activating protein 1 IGELGAPEVWGLS(1)PK;IGELGAPEVWGLS(1)PK;IGELGAPEVWGLS(1)PK;IGELGAPEVWGLS(1)PK;IGELGAPEVWGLS(1)PK 143.67 6.2609e-07 475568600.0 868257.2300000001 905763.63 624965.7 965729.61 964063.3 757710.2 974938.8 823382.7999999999 689709.73 712492.53 True False 1015236.0301770188 995681.857203108 639867.2524836157 911622.9108893408 775162.0169513052 717974.5432394262 882585.5389183377 801769.8739461898 699795.4299986351 841661.7856012344 1.2062280212137624 1.1829952057189463 0.7602427286472696 1.0831226111069427 0.9209899156792231 0.8530440083204524 1.0486225631449688 0.9526033944542841 0.8314449366365633 1.0 19.682881089842525 -5.158656450014797 8.294661003878586 0.9361959408963709 1.1988188562852342 0.5580905753739965 0.09370266997518141 0.21330998382185426 15.52640927670507 0.022738747432863162 0.06073883083199066 6.939745596504533e-06 5.158656450014797 0.2626229153888633 IGELGAPEVWGLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 IGELGAPEVWGLSPK 15 0 A0A494C050;Q8N5F7 A0A494C050 NKAP NF-kappa-B-activating protein 1 IGELGAPEVWGLS(1)PK;IGELGAPEVWGLS(1)PK;IGELGAPEVWGLS(1)PK 167.92 0.00010488 565432000.0 335182.6 306878.3 255915.6 293838.8 309266.6 258191.7 264545.41 272148.5 246517.8 269802.0 True False 330402.8346590387 306167.742150896 234875.20723078324 315448.6855695023 291076.1466295297 247149.44286524944 278242.27689916786 284793.51283694484 218752.36941648266 316436.91621143353 1.0441349214712785 0.9675474840815476 0.7422497034885992 0.9968770058381212 0.9198552119470204 0.7810385900111342 0.8792977767273361 0.9000009109134867 0.6912985123085923 1.0 18.271558391973173 -6.6159418671772485 9.522208452112716 0.8460168775061642 0.929897760939846 0.1370148659804039 0.1049098954137157 0.6634626554806089 61.93489977048818 0.034195197438891885 0.034180706206980875 2.4213531371362405e-07 6.6159418671772485 0.08388088343368183 IGEPVWLTMMS(ph)GT(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IGEPVWLTMMSGTPEK 16 0 J3KNG8;Q8TF40;Q8TF40-2;Q8TF40-3;A0A087WX11 J3KNG8 FNIP1 Folliculin-interacting protein 1 2 IGEPVWLT(0.401)MMS(0.599)GT(1)PEK 58.268 0.044078 0.0 0.0 608.05 707.93 867.09 0.0 0.0 632.03 722.69 0.0 805.41 True False 0.0 668.4131855375447 724.809736039476 818.5097584437092 0.0 0.0 572.1595428990578 703.7201532533498 0.0 951.4244573779479 0.0 0.7025394190303239 0.7618153290246453 0.8602992619082536 0.0 0.0 0.6013714893097085 0.7396490050221624 0.0 1.0 9.893945301562754 -10.71275642576499 4.9890425564636205 1.0000516632607168 0.4312558240357799 0.20117582477039941 0.35141352898664885 0.00020925969773843417 3.3980056851682294e-05 0.3525902269082376 0.08550795432860213 1.9375083115954163e-11 10.71275642576499 -0.5687958392249369 IGEVSS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 IGEVSSPK 8 0 P35251-2;P35251;A0A1W2PP02 P35251-2 RFC1 Replication factor C subunit 1 1 IGEVS(0.136)S(0.864)PK;IGEVS(0.045)S(0.955)PK;IGEVS(0.028)S(0.972)PK;IGEVS(0.037)S(0.963)PK 104.42 0.0038583 101973900.0 1254352.0 1357098.0 1071792.0 1025932.0 1134754.0 1278085.0 1429660.0 1148800.0 1395240.0 1310319.0 True False 1653209.843857595 1795753.3890021811 1057579.337783548 789419.2278913936 977212.9943798234 1198166.1429065175 1556896.9703815933 971279.356797786 1468989.5379610853 1264445.1306400658 1.3074587451815607 1.420190837457032 0.8363979678961619 0.6243206674312449 0.7728393828249039 0.9475825513282671 1.2312886756845571 0.768146701870821 1.1617661394429022 1.0 20.270073003343136 -5.260424812945829 24.97760930092794 0.9061144312625102 1.3638248266080588 0.5065229715766757 0.17579815978334076 69.83132137161945 1719117.1522546506 0.04782603772553953 0.11270764472449203 5.490035934021996e-06 5.260424812945829 0.4577103953455486 IGEVSS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IGEVSSPK 8 0 P35251-2;P35251;A0A1W2PP02 P35251-2 RFC1 Replication factor C subunit 1 1 IGEVS(0.122)S(0.878)PK;IGEVS(0.276)S(0.724)PK;IGEVS(0.203)S(0.797)PK;IGEVS(0.057)S(0.943)PK 131.52 0.0039686999999999995 89669000.0 771346.0 971620.0 646843.0 918950.0 855337.0 643846.0 902230.0 764442.0 608195.0 590042.0 True False 901919.6430220616 1068076.0123871216 662266.1902857387 867464.2107760989 687739.8549380315 610081.582333895 816764.2428204614 744376.2074932487 617088.7012831026 697011.9438300995 1.293980183561832 1.5323640030011751 0.9501504187239145 1.2445471249880733 0.9866973744508342 0.8752813889837815 1.1718081017841957 1.0679533027839971 0.8853344720209291 1.0 19.410823852419774 -5.264867151377403 24.99945703249083 1.0318429890348781 1.413172104619511 0.6181727038309577 0.12257763343672659 173.25353693389718 1263583.9784910246 0.031397323268735254 0.06984783776903816 5.4341653461183e-06 5.264867151377403 0.3813291155846328 IGEVSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 IGEVSSPK 8 0 P35251-2;P35251;A0A1W2PP02 P35251-2 RFC1 Replication factor C subunit 1 1 IGEVS(0.036)S(0.964)PK;IGEVS(0.157)S(0.843)PK 84.81700000000001 0.013691 110204000.0 478050.0 732680.0 558410.0 669830.0 673260.0 575790.0 683580.0 695830.0 529820.0 552790.0 True False 471232.9193363669 730983.5244757246 512499.6853249341 719091.5326873772 633660.1704800889 551164.8039320468 718972.4276173715 728160.8020523041 470146.09234806127 648339.0149536239 0.726831038187752 1.1274711341072268 0.7904810191957884 1.109128891061437 0.9773593071911846 0.8501182116449862 1.1089451830518022 1.1231173587546477 0.7251547130503802 1.0 19.306388866708318 -4.738367399320232 24.701480031292718 0.9810774055327821 0.7268298183563295 0.2280834236182575 0.13917595177115122 2541.1736983905303 2720485.6068788324 0.032734308263140874 1.8104556721927278 1.8265543554639126e-05 4.738367399320232 -0.25424758717645257 IGFPS(ph)TSPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IGFPSTSPAK 10 0 Q9UDT6-2;Q9UDT6 Q9UDT6-2 CLIP2 CAP-Gly domain-containing linker protein 2 1 IGFPS(0.476)T(0.048)S(0.476)PAK;IGFPS(0.754)T(0.123)S(0.123)PAK 133.91 0.00011049 48029100.0 297042.0 261439.0 276621.0 340444.0 338090.0 316688.0 335562.0 328161.0 294975.0 232155.0 True False 347325.3437530746 287392.936129842 283216.6937309843 321370.02641434025 271843.69149937166 300080.32378263806 303775.1381015046 319547.1214653203 299288.4513371255 274242.8637620317 1.2664881739801936 1.0479504632770353 1.0327222004826329 1.1718446270791647 0.9912516510739843 1.0942137916231296 1.1076865736243875 1.1651975810119908 1.0913263055655171 1.0 18.06509455432115 -8.699949046623356 0.009351700887688942 1.5120677226144544e-05 2.1511646593225215 0.14174867179567407 0.07541186860187123 5695.000990457576 29.551167320264394 3452.281878790253 3341.3979603847565 1.995496421826382e-09 8.699949046623356 2.1511495386452952 IGFPS(ph)TSPAK ddPTM_PC-9_Lapatinib_30min_R1 1 IGFPSTSPAK 10 0 Q9UDT6-2;Q9UDT6 Q9UDT6-2 CLIP2 CAP-Gly domain-containing linker protein 2 1 IGFPS(0.843)T(0.078)S(0.078)PAK 144.7 0.00013451 39113000.0 490510.0 432000.0 433980.0 439530.0 450860.0 391060.0 371700.0 375600.0 458350.0 358660.0 True False 483515.2374514817 430999.73054200027 398299.83961124596 471854.50242909667 424341.30122486496 374335.27540538483 390944.8072579323 393051.74719521287 406725.7963605254 420653.9031155897 1.1494371830863972 1.0245946307636369 0.9468587754950626 1.1217166866497321 1.008765871615512 0.8898889862493986 0.9293740159365792 0.9343827414510114 0.9668893913692345 1.0 18.68227420509337 -6.553065641212252 7.350764154520331 0.9398102841982751 1.051881610450617 0.4743291469973676 0.05758761323854801 0.1746341827740988 32.247716592989065 0.019014615048715513 0.019186881438366502 2.79855830103645e-07 6.553065641212252 0.11207132625234195 IGFPSTS(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 1 IGFPSTSPAK 10 0 Q9UDT6-2;Q9UDT6 Q9UDT6-2 CLIP2 CAP-Gly domain-containing linker protein 2 1 IGFPS(0.003)T(0.13)S(0.867)PAK 155.53 0.0002826 48203000.0 350250.0 330330.0 365850.0 481640.0 425210.0 426940.0 381790.0 393140.0 387470.0 426970.0 True False 461622.21434742614 437102.71254477557 360998.58995785686 370605.33926382125 366176.9311588632 400243.3743080542 415768.570374768 332389.24645846273 407950.87316431676 412021.91025955393 1.1203826856116132 1.0608724964879221 0.8761635752099813 0.899479687937852 0.8887316961571033 0.9714128407781037 1.0090933516444645 0.806727113733038 0.9901193674562777 1.0 18.65236153267619 -5.109511948152095 4.351195284457078 0.9254086026772267 1.1084636169056425 0.527817625461189 0.06152079158449283 0.15575852409227836 4.764915017783034 0.015506082997595368 0.04715681844992348 7.771199386579976e-06 5.109511948152095 0.18305501422841586 IGFPSTS(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IGFPSTSPAK 10 0 Q9UDT6-2;Q9UDT6 Q9UDT6-2 CLIP2 CAP-Gly domain-containing linker protein 2 1 IGFPS(0.216)T(0.038)S(0.746)PAK 121.29 0.00063498 37891000.0 95695.0 83343.0 80060.0 98204.0 103640.0 89725.0 96479.0 100110.0 76214.0 69346.0 True False 111894.27343759604 91616.74224530133 81968.93402924069 92701.94826166355 83332.48598596502 85019.66304816483 87339.81067252855 97482.21857531286 77328.48556727769 81917.8808573659 1.3659322270851286 1.1183973668071678 1.0006232237863144 1.1316448532534025 1.0172685757223408 1.037864531630154 1.0661873788532594 1.1899992718933652 0.943975659012967 1.0 16.321890774134026 -4.780296770264796 3.3551154961138416 1.0571832970155675 1.407258165043931 0.667935995223286 0.0668515702866127 0.17992362682725563 3.2087084886724795 0.016043080300021797 0.16438787674155728 1.6584532347174307e-05 4.780296770264796 0.35007486802836363 IGFPSTT(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 1 IGFPSTTPAK 10 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0;F5H0N7 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 IGFPS(0.023)T(0.034)T(0.943)PAK 91.70100000000001 0.013594 0.0 331360.0 275460.0 375200.0 255410.0 284570.0 267700.0 265620.0 222770.0 304850.0 188640.0 True False 326634.7456360189 274822.1892942119 344352.50431388424 274193.70342278323 267832.1520861463 256251.09503917946 279372.5039113584 233120.70746186833 270514.582787185 221246.17265300007 1.4763407733534404 1.242155676632833 1.5564224238760627 1.239315013384776 1.2105617415864234 1.1582170754252128 1.2627224261615726 1.0536711422687168 1.222685931889348 1.0 17.75529297260512 -4.26988665423886 0.16725750181247503 0.9568925934841552 1.9602843489422925 0.5886864777185359 0.10273935326090303 17.206780035027 0.4265110215152153 0.335292871169504 3.7623623790045633 5.371719736558451e-05 4.26988665423886 1.0033917554581373 IGFPWSEIR ddPTM_PC-9_AZD4547_30min_R2 1 IGFPWSEIR 9 0 P15311;E7EQR4;A0A2R8Y7M3;A0A2R8Y5S7;P35241;P35241-5;P35241-4;P26038 P15311;A0A2R8Y7M3;P26038 EZR;RDX;MSN Ezrin;Radixin;Moesin 0 131.03 0.005744399999999999 7952500.0 21087.0 18851.0 26164.0 31807.0 36531.0 21389.0 22533.0 32198.0 16754.0 24638.0 False True 27792.227363152513 24944.217098603123 25817.048264746096 24474.387563251326 31459.301220960097 20051.542448763183 24538.39334779494 27222.538936433815 17639.58223603111 23775.43111922356 1.1689473567813113 1.0491594021373831 1.0858708780204533 1.0293982658199887 1.3231853110551492 0.8433724018804675 1.0320903635667196 1.1449861329506286 0.7419248108510081 1.0 14.53718388122106 -6.782228339107135 24.999677021804363 0.9665124092559686 1.1185619180559154 0.3266393031018384 0.12693421852242037 341.07411039851024 410154.40678379324 0.04367290906005574 0.038556397026981375 1.6510934741933934e-07 6.782228339107135 0.15204950879994683 IGFPWSEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IGFPWSEIR 9 0 P15311;E7EQR4;A0A2R8Y7M3;A0A2R8Y5S7;P35241;P35241-5;P35241-4;P26038 P15311;A0A2R8Y7M3;P26038 EZR;RDX;MSN Ezrin;Radixin;Moesin 0 ; 120.62 0.0076760000000000005 20602100.0 26298.0 24643.3 30219.0 31518.0 37304.0 30913.0 28994.0 29679.0 27236.0 25125.6 False True 30749.731990824035 27089.72396210408 30939.53556619569 29752.14864273468 29994.548989004634 29291.867860773662 26247.478421618085 28899.957697499853 27634.27497455027 29680.67238585985 1.036018712482858 0.9127058716840215 1.0424135667807706 1.0024081751230434 1.0105751176747033 0.9869004138440133 0.8843289693842189 0.9736961926532387 0.9310528621216647 1.0 14.857236154687335 -7.023811267284143 24.178590171942705 0.9437256802863591 0.9983683821070867 0.25528632388881634 0.043144543038877166 669.7918366381052 680122.2525364286 0.015609759967256803 0.01217354765971881 9.466484599815805e-08 7.023811267284143 0.05464270182072761 IGFPWSEIR ddPTM_PC-9_Lapatinib_30min_R1 2 IGFPWSEIR 9 0 P15311;E7EQR4;A0A2R8Y7M3;A0A2R8Y5S7;P35241;P35241-5;P35241-4;P26038 P15311;A0A2R8Y7M3;P26038 EZR;RDX;MSN Ezrin;Radixin;Moesin 0 ; 148.99 0.0013625 22981300.0 47082.0 41574.0 44005.0 40826.0 47945.0 41352.0 39289.0 33953.0 40238.0 37698.0 False True 46410.60204621866 41477.737957298974 40387.07876421225 43828.48023154355 45124.96936349673 39583.47135622016 41323.192177446566 35530.58033152043 35705.97271507544 44214.04907057249 1.0496799777857968 0.9381121799338953 0.9134444732656853 0.9912794949312715 1.020602507847003 0.8952690872767339 0.9346167800982972 0.8036038562043505 0.8075707487926104 1.0 15.432217240205254 -7.193863642324683 1.8602877103597393 0.8615196890910392 0.9748258135557812 0.30296428041289925 0.0664907948231505 0.39808467638387435 2.6990366573714346 0.03317218643426613 0.021933303524900933 6.399357278598563e-08 7.193863642324683 0.11330612446474209 IGGIGT(ph)VPVGR ddPTM_PC-9_AZD4547_30min_R2 1 IGGIGTVPVGR 11 0 Q5VTE0;P68104;A0A087WVQ9;A0A2U3TZH3;Q05639 Q5VTE0 EEF1A1P5;EEF1A1;EEF1A2 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 2 1 IGGIGT(1)VPVGR 80.87100000000001 0.038356 11995000.0 40523.0 45391.0 46324.0 69502.0 65760.0 48074.0 36831.0 70221.0 42152.0 49097.0 True False 53408.47106923837 60062.75308061612 45709.71349243607 53479.3876951958 56630.35910022542 45067.925180318955 40108.88764889877 59369.957968051436 44380.068664986466 47378.12897396371 1.127281136378108 1.2677316386559536 0.9647851125052975 1.128777958382126 1.1952848355693027 0.9512390243414993 0.8465696834702001 1.2531089609021442 0.9367205844995524 1.0 15.531933605284978 -6.763728812253683 24.999994349484833 1.0039120848210565 1.1340487103203196 0.25024644887933667 0.12021020534709523 98.88431856477152 1079778.7605024115 0.04168695744128953 0.03852685890905766 1.7229441020706769e-07 6.763728812253683 0.13013662549926308 IGGIGTVPVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IGGIGTVPVGR 11 0 Q5VTE0;P68104;A0A087WVQ9;A0A2U3TZH3;Q05639 Q5VTE0 EEF1A1P5;EEF1A1;EEF1A2 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 2 0 112.11 0.0079654 29088000.0 53980.0 47740.0 66220.0 64973.0 64462.0 52548.0 51765.0 54725.0 48270.0 43382.0 False True 63117.74784640213 52479.31169733143 67798.93594074866 61332.773455308066 51831.13384433891 49792.29037453289 46861.44445385457 53288.526735930434 48975.857432131816 51246.81318827694 1.2316423972455082 1.0240502468812331 1.3229883327897964 1.196811462792351 1.0114020876559724 0.9716173021647172 0.9144265084677392 1.039840790492716 0.9556859126478402 1.0 15.645174672159373 -6.315939033087691 4.315768398921424 0.9771766528635547 1.1916404995060084 0.6585704280141047 0.07492467504272893 0.1380783526137573 5.437495180311211 0.023550157845164274 0.02747301091224604 4.831266193206916e-07 6.315939033087691 0.21446384664245366 IGGIGTVPVGR ddPTM_PC-9_Lapatinib_30min_R1 2 IGGIGTVPVGR 11 0 Q5VTE0;P68104;A0A087WVQ9;A0A2U3TZH3;Q05639 Q5VTE0 EEF1A1P5;EEF1A1;EEF1A2 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 2 0 ; 104.01 0.012604 137387000.0 430900.0 418530.0 511600.0 484030.0 535070.0 507450.0 523660.0 488000.0 484040.0 480700.0 False True 424755.2869826177 417560.91949940607 469538.22283310944 519627.18087674613 503598.23458809475 485747.5464237264 550772.5525119421 510674.26153158775 429522.31803283223 563788.3545075116 0.7533949284100697 0.7406341691185867 0.8328271044960961 0.9216706530425912 0.8932398666304575 0.8615778288787882 0.9769136735593994 0.9057907235024022 0.761850284062775 1.0 19.104794152650612 -5.46620231000392 2.9992651508423727 0.8998455087712708 0.7467507021874717 0.5078151729257339 0.06117311108084601 0.2096226588293236 3.6895505469040994 0.016648652148811192 0.038062820562414994 3.4182017327795482e-06 5.46620231000392 -0.15309480658379904 IGGNEGIDVPIPR ddPTM_PC-9_Lapatinib_30min_R1 1 IGGNEGIDVPIPR 13 0 Q96AE4;E9PEB5;Q96AE4-2 Q96AE4 FUBP1 Far upstream element-binding protein 1 0 103.21 0.007162100000000001 3674200.0 19747.0 21907.0 21706.0 16506.0 21414.0 20138.0 15840.0 17509.0 16678.0 15818.0 False True 19465.404158843703 21856.275687462054 19921.41646758303 17719.90630240185 20154.47062154385 19276.744683970825 16660.117694284756 18322.532059747038 14799.54801287411 18552.120223839873 1.0492280086580208 1.1781012317598216 1.0738080729976933 0.9551418430132524 1.0863702034253164 1.039058848874847 0.8980169109122174 0.9876246940337413 0.7977281213311874 1.0 14.179296453814588 -7.1663531168249275 4.179340081703811 0.9197095149649955 1.0681164332562854 0.4860308581041106 0.07227457432545527 0.20648338174552622 6.379964165696071 0.028963693993878426 0.02194022726066713 6.817841226338502e-08 7.1663531168249275 0.14840691829128982 IGHHS(ph)TSDDSSAYR ddPTM_PC-9_AZD4547_30min_R2 4 IGHHSTSDDSSAYR 14 0 F5H5P2;P12694;P12694-2;F5GXU9 F5H5P2 BCKDHA 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 1 IGHHS(0.966)T(0.031)S(0.002)DDSS(0.001)AYR;IGHHS(0.798)T(0.18)S(0.016)DDS(0.002)S(0.004)AYR;IGHHS(0.947)T(0.041)S(0.012)DDSSAYR;IGHHS(0.941)T(0.056)S(0.003)DDSSAYR 112.03 0.00019433 93151000.0 77204.0 73577.0 192850.0 314113.0 231202.0 227352.0 164773.0 323370.0 192774.0 198606.0 True False 101753.26605704107 97359.32637334481 190292.68299404855 241699.10084747252 199103.5931370185 213135.64349951915 179437.47779240285 273400.5968033609 202963.640084079 191652.86439096153 0.5309248384071624 0.5079982847255391 0.9929028903312487 1.2611296033354313 1.0388761669163362 1.1120921368789662 0.9362629583576693 1.4265406242279708 1.0590169926708952 1.0 17.548136034859375 -5.332746938557792 3.661505535528432 1.125667582623802 0.5100682365424694 0.7596388913047694 0.13265235373958822 0.09910073573093625 2.572837933634744 0.03460705822400059 0.08325970267468992 4.647860250600614e-06 5.332746938557792 -0.6155993460813327 IGHHS(ph)TSDDSSAYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IGHHSTSDDSSAYR 14 0 F5H5P2;P12694;P12694-2;F5GXU9 F5H5P2 BCKDHA 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 1 IGHHS(0.974)T(0.025)S(0.001)DDSSAYR;IGHHS(0.83)T(0.142)S(0.024)DDS(0.001)S(0.003)AYR 106.76 0.00047918 43371000.0 50840.0 57861.0 127481.0 98427.0 152123.0 130866.0 105888.0 64784.0 100919.0 90796.0 True False 59446.207864228985 63605.057689972666 130520.63051438483 92912.4542946396 122315.59017409278 124003.15658357339 95857.52207726779 63083.48864432188 102394.74945500957 107256.59605925951 0.5542429095119225 0.5930176793493496 1.2169007344058531 0.8662633134777581 1.1404015665993459 1.1561354838732842 0.8937214642193781 0.5881548637760993 0.9546708847485356 1.0 16.710706847656894 -5.164140709839515 8.020617545531248 0.9673274622576095 0.5671478099067512 0.47346892937037643 0.17000243332676068 0.27910671437919016 20.598517762757076 0.046443151658588845 0.12423738820743953 6.852661667247256e-06 5.164140709839515 -0.4001796523508583 IGHHS(ph)TSDDSSAYR ddPTM_PC-9_Lapatinib_30min_R1 3 IGHHSTSDDSSAYR 14 0 F5H5P2;P12694;P12694-2;F5GXU9 F5H5P2 BCKDHA 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 1 IGHHS(0.963)T(0.028)S(0.008)DDSSAYR;IGHHS(0.868)T(0.115)S(0.016)DDSSAYR;IGHHS(0.828)T(0.16)S(0.012)DDSSAYR 107.82 0.00042151 40774000.0 94007.0 70890.0 123084.0 71069.0 94920.0 98905.0 67162.0 77199.0 144456.0 63818.0 True False 92666.44294122746 70725.85856046862 112964.50863797983 76295.65133923398 89336.99221990007 94675.06370881596 70639.31973381009 80785.94736880546 128185.84409088266 74848.85626786019 1.2380475475751267 0.9449156885893263 1.509234933847431 1.0193295548324235 1.1935652283074503 1.2648832384292432 0.9437595075736961 1.0793210664395234 1.7125958963507257 1.0 16.191692650819206 IGHPAPNFK ddPTM_PC-9_AZD4547_30min_R2 2 IGHPAPNFK 9 0 A0A0A0MSI0;Q06830;A0A0A0MRQ5 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 ; 120.46 0.0014065999999999998 65235000.0 546400.0 607410.0 677130.0 928300.0 822070.0 689540.0 616990.0 777330.0 603190.0 646820.0 False True 720143.8341739696 803743.4039500558 668150.8137711177 714294.777092031 707939.7704611061 646422.9547954631 671900.9147319936 657211.509766387 635073.391963209 624175.0286766854 1.1537530357482384 1.287689136898145 1.0704542525318026 1.1443821753113204 1.1342007256554472 1.035643729878053 1.0764623444749013 1.0529282325820408 1.01746042822256 1.0 19.251591115056726 -5.639359536597787 0.32846078608512247 0.9987905912305384 1.3007829975686631 0.6237894181484328 0.04974658843046149 2.5230779219119133 0.3367468446068177 0.05335491976382359 0.2906323511253986 2.2942485368274193e-06 5.639359536597787 0.30199240633812474 IGHPAPNFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IGHPAPNFK 9 0 A0A0A0MSI0;Q06830;A0A0A0MRQ5 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 ; 96.492 0.0042699 70524000.0 490960.0 505150.0 535440.0 613940.0 690520.0 559550.0 587010.0 552050.0 529570.0 498430.0 False True 574069.83109799 555297.9535799532 548206.9202675085 579542.9322203357 555217.562939295 530206.2129685215 531404.1632156321 537559.2724453238 537313.9594019908 588791.4134302904 0.9749969479912545 0.9431148975913137 0.9310715267970073 0.9842924319224134 0.9429783625827783 0.9004992275270246 0.9025338194381589 0.912987622074023 0.9125709837913689 1.0 19.167397106613215 -6.554107698590059 8.468619036454932 0.9190715205183507 0.9563641097308588 0.1887747308358232 0.030314816543240766 0.3338297919556081 80.35320545524382 0.009500302348275431 0.009550589832523451 2.7918514176426444e-07 6.554107698590059 0.03729258921250811 IGHPAPNFK ddPTM_PC-9_Lapatinib_30min_R1 2 IGHPAPNFK 9 0 A0A0A0MSI0;Q06830;A0A0A0MRQ5 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 ; 113.41 0.0017649999999999999 111926000.0 1351910.0 1206900.0 1290510.0 1160540.0 1232410.0 1162690.0 1208410.0 1161850.0 1201020.0 1059080.0 False True 1332631.515490067 1204105.4972017126 1184409.2493126588 1245889.9830479482 1159922.0668112834 1112964.4590627693 1270975.5570044606 1215833.7925419563 1065748.4802987196 1242140.5668646086 1.0728508117675235 0.9693794159231885 0.9535227178855656 1.003018511981139 0.9338090210990695 0.8960052418802298 1.0232139509078564 0.9788214192303087 0.8579934580100422 1.0 20.244397014737153 -4.756744149897816 3.7940939616731617 0.9563891092988882 1.0880205903717164 0.34717791188682257 0.04784642942719542 0.3251134658588061 8.121640079589481 0.011912665590282931 0.12465387745621039 1.75087785612034e-05 4.756744149897816 0.13163148107282818 IGLETVGVK ddPTM_PC-9_Lapatinib_30min_R1 2 IGLETVGVK 9 0 Q16881;Q16881-5;A0A182DWI3;Q16881-2;F8W809;Q16881-3;Q16881-6;Q16881-4;A0A087WSW9;E9PIR7;A0A087WSY9;Q16881-7;E2QRB9;E9PRI8 Q16881 TXNRD1 Thioredoxin reductase 1, cytoplasmic 0 ; 135.83 0.004774100000000001 12223000.0 64566.0 63405.0 60678.0 67003.0 62537.0 57460.0 55178.0 58234.0 64382.0 58553.0 False True 63645.277000045724 63258.1896180916 55689.289063853445 71930.62413545564 58858.69661247252 55002.56974580215 58034.846851972485 60939.764233668924 57130.62118748415 68673.80803303166 0.9267765808098593 0.9211399721370456 0.8109247274749531 1.0474244285515297 0.8570763482951443 0.8009250006836125 0.8450797838974955 0.8873800067175144 0.8319128183485134 1.0 16.067472344300775 IGNLQTDLSDGLR ddPTM_PC-9_Lapatinib_30min_R1 2 IGNLQTDLSDGLR 13 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 106.26 0.0052448 6588400.0 24189.0 21929.0 20290.7 23414.0 27334.0 22337.2 24737.0 20950.4 22473.6 19838.8 False True 23844.060424280677 21878.224747813736 18622.476970367054 25135.943666814306 25726.267860711658 21381.890026556433 26017.760820929405 21923.832067195402 19942.386510500506 23267.910146460632 1.0247615825483873 0.9402745932101562 0.8003502185261699 1.0802836829176008 1.105654427010282 0.9189432953783738 1.1181821081979322 0.9422346884268984 0.8570768231857736 1.0 14.50605401759252 -4.722637872960177 22.183612056195834 0.9767077677020038 1.0247632102383557 0.022340984746259007 0.09958854473505262 9680.039286160298 5532864.607362504 0.025556438425047838 5.411504368502406 1.893922166379758e-05 4.722637872960177 0.048055442536351856 IGPLGLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 IGPLGLSPK 9 0 P30050 P30050 RPL12 60S ribosomal protein L12 1 IGPLGLS(1)PK 74.944 0.026691000000000003 79105000.0 97059.0 60773.0 76177.0 77514.0 75666.0 64653.0 67376.0 67472.0 68129.0 72193.0 True False 127921.74304738545 80416.68376921152 75166.84320683245 59644.34487936183 65161.08199023197 60610.23768946128 73372.33347539307 57045.752752315726 71730.15985188985 69665.5450438391 1.8362268315978425 1.1543250500460012 1.0789672737008158 0.8561527056427803 0.9353415946035797 0.8700174189596953 1.0532083460944914 0.8188517396428608 1.0296360963909998 1.0 16.088157688662236 -4.248874282594221 1.279158437061685 0.9351458487505047 3.8693623948814815 0.9154191452169504 0.08057482573610687 1.121345388103804 0.6236851469030701 0.022083430954609615 6.029006716539406 5.63800838467681e-05 4.248874282594221 2.934216546130977 IGPLGLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 IGPLGLSPK 9 0 P30050 P30050 RPL12 60S ribosomal protein L12 1 IGPLGLS(1)PK;IGPLGLS(1)PK 69.65 0.039793 117166000.0 174666.0 135502.0 145185.0 157454.0 150126.0 124730.0 123610.0 123594.0 118425.0 125600.0 True False 172175.2308101785 135188.25344421828 133248.44973030715 169033.69241114656 141295.88383907202 119395.58865983125 130009.920971625 129336.62844207961 105086.72942946496 147309.79264852006 1.1687969123749102 0.9177139619412562 0.9045457693925132 1.1474708461131267 0.9591750914767956 0.8105068000788525 0.8825612923224161 0.8779907032431695 0.7133723260353847 1.0 17.168493813404346 -6.58549915371376 5.347303842564018 0.8522238010740214 1.0212652701006055 0.39511664199135865 0.10328307690003956 0.21478188657365932 12.113036830494329 0.03384330210585778 0.03401729150118532 2.597172802367679e-07 6.58549915371376 0.16904146902658412 IGPLGLSPK ddPTM_PC-9_Lapatinib_30min_R1 2 IGPLGLSPK 9 0 P30050 P30050 RPL12 60S ribosomal protein L12 0 ; 95.815 0.024442 14766300.0 114487.0 121903.0 140957.0 135950.0 122286.0 113511.0 131321.0 109833.0 114810.0 115004.0 False True 112854.39438565545 121620.74109319816 129368.05956975471 145948.21651590534 115093.3779035261 108656.3991370649 138120.15882141204 114936.2421450793 101878.8887971024 134882.28816680273 0.8366880182674067 0.9016805893950686 0.9591182158014044 1.082041374738675 0.8532875551547243 0.8055646194457684 1.0240051581168699 0.8521225707777358 0.7553170262882363 1.0 17.041341390168846 IGPPS(ph)PGDDEEEAAAAAGAPAAAGATGDLASAQLGGAPNR ddPTM_PC-9_AZD4547_30min_R2 1 IGPPSPGDDEEEAAAAAGAPAAAGATGDLASAQLGGAPNR 40 0 H0Y6K5;A0A494C070;Q02447-2;Q02447 H0Y6K5 SP3 Transcription factor Sp3 1 IGPPS(1)PGDDEEEAAAAAGAPAAAGATGDLASAQLGGAPNR 97.61 2.378e-20 5752200.0 11526.0 13626.0 18862.0 16849.0 15013.0 18765.0 16588.0 19643.0 15056.0 16716.0 True False 15191.02824430672 18030.338029047063 18611.87755578813 12964.72336445504 12928.704093243368 17591.62158357293 18064.29986478599 16607.625701235153 15851.8294225668 16130.777927954417 0.9417418249854446 1.117759980924462 1.1538115296680145 0.8037258601141208 0.8014929069749389 1.0905625049295913 1.119865386868962 1.0295613624718225 0.9827070643069108 1.0 13.977528395584175 -9.695555926352633 15.641584484389922 1.0000009883396568 1.007072493990727 0.0 0.11935544510203075 0.0 0.0 0.12537922049295164 0.03040892760882624 2.0157843709426632e-10 9.695555926352633 0.007071505651070176 IGPPS(ph)SPSATDKEENPAVLAENCFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IGPPSSPSATDKEENPAVLAENCFR 25 1 A0A1B0GUZ7;Q14156-3;Q14156-2;Q14156 A0A1B0GUZ7 EFR3A Protein EFR3 homolog A 1 IGPPS(0.412)S(0.354)PS(0.117)AT(0.117)DKEENPAVLAENCFR 45.243 0.022444 3621300.0 6660.7 8160.7 6046.4 6233.4 12471.0 8583.5 7648.6 11447.0 8409.5 7913.4 True False 7788.2249551784025 8970.840363812586 6190.569107099693 5884.162806955467 10027.397073822562 8133.366149611845 6924.069236931368 11146.528379099049 8532.473028289043 9348.036777560063 0.833140170551534 0.9596496651946282 0.6622320016926054 0.6294543920794561 1.0726741146219387 0.8700614196486656 0.7406976889043246 1.192392439646393 0.9127556118276323 1.0 13.190447694724112 -7.7501300583492 24.985784404958398 1.0394305508405501 0.826838457279852 0.3245484410797095 0.13944772202655176 251.6664792525405 556011.8107507167 0.06803590319736419 0.03883018724014616 1.7777469476964195e-08 7.7501300583492 -0.2125920935606982 IGPPSS(ph)PSATDKEENPAVLAENCFR ddPTM_PC-9_AZD4547_30min_R2 1 IGPPSSPSATDKEENPAVLAENCFR 25 1 A0A1B0GUZ7;Q14156-3;Q14156-2;Q14156 A0A1B0GUZ7 EFR3A Protein EFR3 homolog A 1 IGPPS(0.173)S(0.759)PS(0.034)AT(0.034)DKEENPAVLAENCFR 53.266000000000005 0.005231 6101000.0 10560.0 19399.0 14036.0 16628.0 13125.0 12831.0 14322.0 18140.0 11720.0 9684.2 True False 13917.86033835494 25669.34738187904 13849.873469040527 12794.67150003908 11302.820303991166 12028.675541637318 15596.630254609652 15336.879815731083 12339.495273145785 9345.159105641074 1.4893122932442764 2.7468068859720214 1.482037203698356 1.3691229175879687 1.2094839880434327 1.2871557782656025 1.6689528854778903 1.6411576991207342 1.320415750406777 1.0 13.190003511389644 -5.452043794953734 11.860435946771792 1.390241313359263 2.11814159137628 0.4416937036802916 0.33648168321217037 0.8743828603670883 144.76118544162426 0.08289396515109806 0.17256116878801972 3.531475560290371e-06 5.452043794953734 0.727900278017017 IGPPSS(ph)PSATDKEENPAVLAENCFR ddPTM_PC-9_Lapatinib_30min_R1 1 IGPPSSPSATDKEENPAVLAENCFR 25 1 A0A1B0GUZ7;Q14156-3;Q14156-2;Q14156 A0A1B0GUZ7 EFR3A Protein EFR3 homolog A 1 IGPPS(0.451)S(0.49)PS(0.029)AT(0.029)DKEENPAVLAENCFR 55.04600000000001 0.0030465 4078900.0 26275.0 32297.0 14368.0 12835.0 17715.0 13545.0 16060.0 13599.0 25174.0 11549.0 True False 25900.31368175512 32222.21828082178 13186.71850208389 13778.928716304854 16673.038529030044 12965.71192493718 16891.508217816496 14230.859185590276 22338.63902602785 13545.229261924815 1.9121354966327542 2.3788610482509407 0.9735323224946302 1.0172532668041996 1.2309159340622897 0.9572161293263128 1.2470448370555056 1.0506178160891484 1.649188699140074 1.0 13.725497191859613 -5.263800075190666 24.99992945077852 1.13858409031005 2.1454983158081995 0.7666248924588352 0.22174845604615212 81.57084444478409 863850.8923074588 0.05491125437237804 0.1236981242979242 5.447533690128009e-06 5.263800075190666 1.0069142254981496 IGQGYLIK ddPTM_PC-9_Lapatinib_30min_R1 2 IGQGYLIK 8 0 P39023;G5E9G0;B5MCW2 P39023 RPL3 60S ribosomal protein L3 0 ; 114.6 0.016911000000000002 14426300.0 83134.0 80237.0 76617.0 85109.0 74864.0 78118.0 79450.0 78771.0 71597.0 63005.0 False True 81948.49391509175 80051.21615624668 70317.8460101726 91368.19977530117 70460.646708287 74777.07524195217 83563.53224816434 82430.9882276735 63532.99191016596 73895.33030111459 1.1089806836394327 1.0833054785741885 0.9515871398589846 1.2364543118352234 0.9535196124189218 1.0119323499501873 1.1308364399706041 1.1155101126387437 0.8597700511152282 1.0 16.17319557796302 -8.254966132675365 24.99423462495102 0.9298850224613391 1.0714671252461765 0.30423999205644436 0.08711608944034936 567.0244405059931 2189392.9063727004 0.05993240937748558 0.021475357803844804 5.559476097071424e-09 8.254966132675365 0.1415821027848374 IGQQVDREPGDVAT(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 4 IGQQVDREPGDVATPPR 17 1 H3BT22;Q9Y5N6 H3BT22 ORC6 Origin recognition complex subunit 6 1 IGQQVDREPGDVAT(1)PPR;IGQQVDREPGDVAT(1)PPR;IGQQVDREPGDVAT(1)PPR;IGQQVDREPGDVAT(1)PPR 133.23 0.00023065 52029000.0 43060.0 43840.4 62526.0 86656.0 79376.0 64572.0 51248.4 80046.0 56958.0 66394.0 True False 56752.184296360225 58010.951954251796 61696.86438623734 66678.79802185399 68356.01252949362 60534.30263226595 55809.40831869411 67676.7299740911 59968.68359793835 64069.56626876071 0.8857900498076522 0.9054369388253062 0.9629667871861299 1.040724979191337 1.0669030010715541 0.9448214832348802 0.8710751698331051 1.0563007355192473 0.9359932818396198 1.0 15.967351603483399 -5.29459122840224 3.314428230014647 0.9876483507993917 0.8916259115072996 0.29132231853278534 0.056806878454717054 0.3174580312167052 7.145147204614549 0.016032954355823227 0.04255200376625421 5.074681284886729e-06 5.29459122840224 -0.09602243929209209 IGQQVDREPGDVAT(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IGQQVDREPGDVATPPR 17 1 H3BT22;Q9Y5N6 H3BT22 ORC6 Origin recognition complex subunit 6 1 IGQQVDREPGDVAT(1)PPR;IGQQVDREPGDVAT(1)PPR;IGQQVDREPGDVAT(1)PPR;IGQQVDREPGDVAT(1)PPR 161.24 0.00031150000000000004 85466000.0 147195.0 150179.0 190690.0 208680.0 233297.0 186289.0 206724.0 171175.0 195727.0 142619.0 True False 172112.20626623146 165087.77862156526 195236.77279585262 196988.33614968788 187584.12758652781 176519.676896958 187141.60616784776 166681.83762490394 198589.13709589472 168474.69572861746 1.0215908420067628 0.9798965827336592 1.158849238168942 1.169245834205279 1.1134261247676756 1.0477518664363672 1.1107994904427627 0.9893582944550825 1.17874756346666 1.0 17.362172394697012 -5.245975698399095 24.86887374742547 1.0976827456678846 1.000743700464218 0.2637095202080687 0.06363366373042913 1001.0369884837143 1609872.9560032804 0.01597589124559126 0.04195237235405435 5.675763641090635e-06 5.245975698399095 -0.0969390452036667 IGQQVDREPGDVAT(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 2 IGQQVDREPGDVATPPR 17 1 H3BT22;Q9Y5N6 H3BT22 ORC6 Origin recognition complex subunit 6 1 IGQQVDREPGDVAT(1)PPR;IGQQVDREPGDVAT(1)PPR 106.39 0.00047552 56870000.0 63475.0 57146.0 65014.0 67592.0 59371.0 49758.0 48904.0 50743.0 67745.0 49361.0 True False 62569.834860110655 57013.6819480398 59668.79988129746 72562.94116030203 55878.914507877074 47629.966331563235 51436.009830890245 53100.705026428936 60114.84471352422 57892.98308060185 1.0807844324241753 0.9848116112562754 1.030674128472931 1.2533978610028755 0.9652104889823923 0.8227243406208682 0.8884670834680976 0.9172217806171633 1.0383787726023543 1.0 15.821100876498175 -6.505896218885107 24.962627899744476 0.9218888599865159 1.0801936461069264 0.42372497538460907 0.08496682464182133 708.2359369437227 1041038.0191757182 0.027492446432693562 0.030441176769942197 3.1196349781275366e-07 6.505896218885107 0.15830478612041043 IGS(ph)DPLAYEPK ddPTM_PC-9_AZD4547_30min_R2 2 IGSDPLAYEPK 11 0 P19634 P19634 SLC9A1 Sodium/hydrogen exchanger 1 1 IGS(1)DPLAYEPK;IGS(0.905)DPLAY(0.095)EPK 129.71 0.00024598 34589000.0 158916.0 350060.0 158426.0 87029.0 117231.0 110701.0 231344.0 145269.0 168567.0 112973.0 True False 209447.98234185748 463210.0492035972 156325.16772629035 66965.80863464651 100955.49920435731 103778.84897005635 251933.16782728772 122821.01399952835 177477.1074836489 109017.84965630475 1.921226505587607 4.248937680058237 1.4339410309332745 0.6142646258916897 0.9260455927413244 0.9519436431486665 2.310935031479204 1.1266138011962277 1.6279637512863472 1.0 16.734204843405458 -7.80955742782663 24.996839800977767 1.2829660128957279 1.7460424088943256 0.05575218776249358 0.975660570957533 515.0438509998872 267553.0929052634 0.5907802968244953 0.2838026249885154 1.550395760597431e-08 7.80955742782663 0.46307639599859773 IGS(ph)DPLAYEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IGSDPLAYEPK 11 0 P19634 P19634 SLC9A1 Sodium/hydrogen exchanger 1 1 IGS(1)DPLAYEPK;IGS(0.999)DPLAY(0.001)EPK;IGS(1)DPLAYEPK 125.03 0.00048152 18922300.0 72483.0 121542.0 48950.5 59036.6 135543.0 69537.3 112740.0 75070.2 74701.9 93106.0 True False 84752.94029549406 133607.88651690554 50117.66556580503 55728.97070123963 108984.3221535668 65890.6415745795 102060.45103308339 73099.68679345172 75794.27396538985 109985.38077330972 0.7705836875736958 1.2147785967326334 0.45567570174714656 0.5066943470978412 0.9908982574529046 0.5990854521873806 0.927945608002573 0.6646309380345474 0.6891304410866115 1.0 16.746952248300417 -5.255842421404786 24.98657470187714 0.7211227451330657 0.9926811067186136 0.20537493480676483 0.20676829749310247 665.275961543744 2969977.7900676895 0.05108801005560966 0.12730781388632914 5.548269888243678e-06 5.255842421404786 0.2715583615855479 IGS(ph)DPLAYEPK ddPTM_PC-9_Lapatinib_30min_R1 1 IGSDPLAYEPK 11 0 P19634 P19634 SLC9A1 Sodium/hydrogen exchanger 1 1 IGS(1)DPLAYEPK 143.55 0.00015341 9470400.0 61493.0 158680.0 39183.0 36758.0 80362.0 60725.0 73515.0 78991.0 98121.0 32882.0 True False 60616.09854356493 158312.5862092701 35961.52499075398 39461.30594109339 75635.26515777099 58127.93330688889 77321.24698834235 82661.21023082275 87069.5797200636 38565.60988748909 1.5717655890936435 4.10501964499277 0.9324765016206863 1.0232252531780879 1.9612101397703428 1.5072478686703183 2.0049273747755723 2.1433917542592407 2.2577000590443013 1.0 15.235027305810997 -5.278863078227836 24.992400935750776 1.6475192841009254 2.8383929623065627 0.31005229776176013 0.7343724415405476 848.2687218793877 1216748.468538026 0.1870372597401421 0.3907835894766603 5.261831321201198e-06 5.278863078227836 1.1908736782056373 IGS(ph)GSFGTVYK ddPTM_PC-9_AZD4547_30min_R2 1 IGSGSFGTVYK 11 0 P04049;P04049-2;H7C155;H7C4S5;H7C560;P15056;A0A2R8Y679;A0A2R8Y492;A0A2R8YDP5;A0A2R8Y8E0;A0A2U3TZI2 P04049;H7C560 RAF1;BRAF RAF proto-oncogene serine/threonine-protein kinase;Serine/threonine-protein kinase B-raf 1 IGS(0.792)GS(0.198)FGT(0.009)VYK 78.548 0.018268 4061600.0 16220.0 17305.0 14048.0 22032.0 18510.0 16624.0 17511.0 15977.0 15598.0 14350.0 True False 21377.62260304138 22898.502832280872 13861.714341199859 16952.862791006795 15940.206005857257 15584.498652028582 19069.44507669805 13508.121764935815 16422.478436051868 13847.610867800064 1.5437769595873683 1.6536067521601798 1.0010184770163197 1.2242445973425924 1.1511159692480324 1.1254286967484994 1.3770927894168628 0.9754839223816099 1.1859430910381197 1.0 13.757349468712178 -5.254817486591832 24.99792409226281 1.1419410195618285 1.5986919058166038 0.7172157572335291 0.11751977387472325 258.2406893042975 974863.1611791822 0.028641958170788268 0.0721246462590214 5.561379266059308e-06 5.254817486591832 0.45675088625477533 IGTEPSTAPAPS(ph)PPAPK ddPTM_PC-9_AZD4547_30min_R2 2 IGTEPSTAPAPSPPAPK 17 0 Q6NV74 Q6NV74 KIAA1211L Uncharacterized protein KIAA1211-like 1 IGTEPSTAPAPS(1)PPAPK;IGTEPSTAPAPS(1)PPAPK 206.13 2.6893e-17 32343000.0 129521.0 138061.0 173000.0 224359.0 216395.0 157457.0 147111.0 203530.0 173241.0 179005.0 True False 170705.98379583957 182686.51831999616 170705.90696380794 172636.49886199602 186352.28949959387 147611.18889872884 160203.59400823098 172079.11515412104 182398.16558148884 172738.08943488193 0.9882359145820678 1.0575925606081487 0.9882354697928967 0.9994118808815227 1.0788141174262795 0.8545375798797096 0.9274364127352691 0.9961851246420709 1.055923254553817 1.0 17.39822671236945 IGTEPSTAPAPS(ph)PPAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IGTEPSTAPAPSPPAPK 17 0 Q6NV74 Q6NV74 KIAA1211L Uncharacterized protein KIAA1211-like 1 IGTEPSTAPAPS(1)PPAPK;IGTEPSTAPAPS(1)PPAPK 208.85 1.613e-17 25180000.0 98068.0 94251.0 99022.0 108607.0 136017.0 109173.0 99407.0 95954.0 95521.0 86313.0 True False 114668.97546870985 103607.61639684114 101383.06002302602 102522.10189864469 109365.44525620433 103447.7756919175 89990.4493156444 93435.30917166661 96917.8139170222 101960.86364666812 1.1246371535855169 1.0161508317140155 0.9943330842543232 1.0055044478038306 1.0726218015884585 1.0145831644816394 0.8825979507931042 0.9163840500160366 0.9505393584432362 1.0 16.63765597312816 -7.110499158807087 5.759505300942865 0.931028972346322 1.0370722560934065 0.551983177000801 0.04465771299753596 0.17683441559289348 7.897516343065907 0.017301058890991813 0.013384484283879517 7.753554451582636e-08 7.110499158807087 0.1060432837470845 IGTEPSTAPAPS(ph)PPAPK ddPTM_PC-9_Lapatinib_30min_R1 2 IGTEPSTAPAPSPPAPK 17 0 Q6NV74 Q6NV74 KIAA1211L Uncharacterized protein KIAA1211-like 1 IGTEPSTAPAPS(1)PPAPK;IGTEPSTAPAPS(1)PPAPK 237.4 1.9220999999999997e-37 28345000.0 148233.0 141634.0 126684.0 102456.0 119821.0 117785.0 103508.0 111020.0 122144.0 88535.0 True False 146119.17023739722 141306.05517496716 116268.53053438172 109990.95602319669 112773.36435714983 112747.61012024549 108867.13777146643 116178.39449843632 108386.85648665878 103838.15678452814 1.4071818564788792 1.3608297715471556 1.1197091140171866 1.0592537409098668 1.0860493661416093 1.0858013432788982 1.0484309539254804 1.1188410705278127 1.0438056668472027 1.0 16.663977154051544 -5.269559719162338 2.91304320897204 1.06967359907608 1.403701235308851 0.9462948629363857 0.030226907153738252 0.049264507882812766 0.8309305577750917 0.007629686419291512 0.022632580501797863 5.375765067258283e-06 5.269559719162338 0.334027636232771 IGTLHTS(ph)PDLK ddPTM_PC-9_AZD4547_30min_R2 3 IGTLHTSPDLK 11 0 Q9UPZ3;Q9UPZ3-2 Q9UPZ3 HPS5 Hermansky-Pudlak syndrome 5 protein 1 IGTLHT(0.01)S(0.99)PDLK;IGTLHT(0.158)S(0.842)PDLK;IGT(0.001)LHT(0.276)S(0.723)PDLK 127.78 0.0001945 35222000.0 321131.0 281834.0 337013.0 386437.0 360660.0 324771.0 305100.0 351099.0 297968.0 340336.0 True False 423243.97806025145 372931.32893574424 332543.98741961736 297349.9200421337 310588.5844447583 304463.01802923286 332253.3089429828 296844.71700239147 313717.98016627185 328420.9402302162 1.2887240922079033 1.1355284735325561 1.012554154392564 0.9053926946122791 0.9457027442496274 0.927051173459922 1.0116690753947668 0.9038544155994119 0.9552313562782024 1.0 18.32518659120891 -5.01019840719781 1.6220201948110138 0.9470737388638436 1.3335360019821454 0.904966297295412 0.035115964094855165 0.17185664360790529 0.6080598057170747 0.00980365919576332 0.0917942438409822 9.76790872627774e-06 5.01019840719781 0.3864622631183018 IGTLHTS(ph)PDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IGTLHTSPDLK 11 0 Q9UPZ3;Q9UPZ3-2 Q9UPZ3 HPS5 Hermansky-Pudlak syndrome 5 protein 1 IGTLHT(0.226)S(0.774)PDLK;IGTLHT(0.022)S(0.978)PDLK 87.863 0.0057472 22353000.0 134041.0 128526.0 130325.0 152703.0 158119.0 138144.0 142753.0 143475.0 128368.0 104547.0 True False 156731.49386957378 141285.21188125707 133432.44226031486 144147.5459798056 127136.71701673856 130899.48545138675 129230.4023977807 139708.9332743283 130245.13915160313 123500.54350640315 1.269075336995968 1.1440047781970437 1.080419878908442 1.1671814705198602 1.0294425709158672 1.0599101974364995 1.0463954143738685 1.1312414448369192 1.054611870148169 1.0 16.914157865333948 -1.5228787453405959 0.6452892836433549 1.0642520952295373 18.278068216304906 0.6748729346921232 0.043381377729749294 128.9102082906469 0.8470746367227663 0.01800758586130745 3166.511979965358 0.029999999995837506 1.5228787453405959 17.213816121075368 IGTLHTS(ph)PDLK ddPTM_PC-9_Lapatinib_30min_R1 1 IGTLHTSPDLK 11 0 Q9UPZ3;Q9UPZ3-2 Q9UPZ3 HPS5 Hermansky-Pudlak syndrome 5 protein 1 IGTLHT(0.171)S(0.829)PDLK 73.877 0.0134 13956000.0 111480.0 89386.0 93292.0 93152.0 85468.0 85890.0 79323.0 72043.0 89862.0 57730.0 True False 109890.27475707204 89179.03220885947 85621.89187753433 100002.70882596275 80440.94027655313 82216.68491936903 83429.95680958012 75390.38078590206 79740.79527118907 67708.55357961041 1.6229895478104577 1.317101422112119 1.2645653665730987 1.4769582798483725 1.1880469456783216 1.2142732427846097 1.2321922770287035 1.1134543096871727 1.1777063761586841 1.0 16.047050479633143 -1.522878745293854 0.15876626704764854 0.9777198303346516 3.0368265342110323 0.7222223107655745 0.08913124640678718 35.65887737564984 0.3672188909057435 0.2719375175290684 17.132673646362136 0.029999999999066322 1.522878745293854 2.0591067038763806 IGVLDEGK ddPTM_PC-9_Lapatinib_30min_R1 2 IGVLDEGK 8 0 P46781;B5MCT8;C9JM19 P46781 RPS9 40S ribosomal protein S9 0 ; 106.04 0.017658 14200900.0 122782.0 99962.0 114739.0 106408.0 120815.0 95594.0 116295.0 101471.0 99909.0 98343.0 False True 121031.10616453884 99730.54413064693 105305.60232534831 114233.5992866821 113708.89923142904 91505.66746049788 122316.18606419486 106185.71309809787 88656.19633158874 115341.45651618963 1.0493287480512317 0.8646548009964525 0.9129900515047453 0.9903949779812948 0.9858458759402657 0.793345863875526 1.0604702745974621 0.9206205323338652 0.7686412068079331 1.0 16.81555162021582 IHAESLLLDS(ph)PAVAK ddPTM_PC-9_AZD4547_30min_R2 4 IHAESLLLDSPAVAK 15 0 Q9H4L5-5;Q9H4L5;Q9H4L5-6;Q9H4L5-2 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 IHAESLLLDS(1)PAVAK;IHAESLLLDS(1)PAVAK;IHAESLLLDS(1)PAVAK;IHAESLLLDS(1)PAVAK 176.29 1.5445e-09 18739100.0 78854.0 69608.6 127280.0 169566.0 138135.0 124361.0 113130.0 146202.0 113434.0 134581.0 True False 103927.93173490888 92108.21867963641 125592.18403672543 130475.17846858467 118957.33963366262 116584.68701064259 123198.35083815016 123609.8402877349 119429.88965989932 129869.36015326847 0.8002498172952868 0.7092374873560066 0.9670655487060595 1.0046648286755337 0.9159769440095202 0.8977074105320327 0.9486329238301833 0.9518014113710405 0.9196156007772059 1.0 16.986701572897715 -5.266173023564131 24.9996230196981 0.947684915828125 0.7547436460568854 0.8055587552874524 0.03848336458579121 145.15371221805157 766598.9639721187 0.010105503707055449 0.02218211714711151 5.417849994534867e-06 5.266173023564131 -0.1929412697712396 IHAESLLLDS(ph)PAVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IHAESLLLDSPAVAK 15 0 Q9H4L5-5;Q9H4L5;Q9H4L5-6;Q9H4L5-2 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 IHAESLLLDS(1)PAVAK;IHAESLLLDS(1)PAVAK 161.2 1.1144e-05 18746100.0 116455.0 123337.0 141363.0 137158.0 178306.0 146720.0 156003.0 141040.0 130162.0 105017.0 True False 136168.53140890598 135581.0822541637 144733.63004216287 129473.48193223597 143368.2192803311 139025.74491420164 141225.26647608745 137337.84944423233 132065.37300768882 124055.7507858852 1.0976398155368623 1.0929044513879143 1.1666821499630984 1.0436717452599318 1.1556757213760962 1.1206715048152343 1.1384016104165624 1.1070655618478458 1.0645646991055486 1.0 16.92062908945735 -8.540722274765594 2.0990751652265645 1.0004925785074048 1.1167202130168232 0.548531005050131 0.032893951535465246 0.2429672909277258 2.4708391921499833 0.030023669262302627 0.008332876761698523 2.8792390591646973e-09 8.540722274765594 0.11622763450941842 IHAESLLLDS(ph)PAVAK ddPTM_PC-9_Lapatinib_30min_R1 3 IHAESLLLDSPAVAK 15 0 Q9H4L5-5;Q9H4L5;Q9H4L5-6;Q9H4L5-2 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 IHAESLLLDS(1)PAVAK;IHAESLLLDS(1)PAVAK;IHAESLLLDS(1)PAVAK 180.62 2.0447999999999998e-05 14911600.0 81196.0 71608.0 92949.0 72778.0 85976.0 90094.0 75789.0 69734.0 91565.0 57404.0 True False 80038.1301504772 71442.19607558237 85307.09201351574 78130.33690029077 80919.06071531949 86240.88963937176 79712.98358157497 72974.09621648314 81251.98547780415 67326.20491397798 1.1888109578245367 1.0611350538302782 1.2670711519015776 1.1604743947786322 1.2018954702512783 1.2809409018310312 1.1839815371061453 1.0838884548701566 1.2068404209270223 1.0 16.038880523925346 -10.587977516435192 5.535089266022748 0.9999987916182049 1.1807206468980136 0.4096528468884094 0.06541735984860098 9.834069391970923e-07 1.6604381114298073e-07 0.06384798312592276 0.015485307122244994 2.5823938785344983e-11 10.587977516435192 0.18072185527980866 IHDENLR ddPTM_PC-9_AZD4547_30min_R2 1 IHDENLR 7 0 O95232;J3KPP4;D6RDI2 O95232 LUC7L3 Luc7-like protein 3 0 177.71 0.00012138 4988300.0 5040.9 2489.6 5067.3 6262.5 5771.4 5256.1 5105.9 6616.4 2498.2 5817.9 False True 6643.801342766423 3294.314513218519 5000.104291084996 4818.777379660499 4970.140731615587 4927.43523610006 5560.315208561054 5593.987409746588 2630.2497518236187 5614.217091830938 1.1833887493295545 0.5867807495388746 0.8906147035818194 0.8583168945625815 0.8852776175768968 0.8776709477924907 0.9903990383007605 0.9963967046956937 0.46849804857934835 1.0 12.454869136053038 -11.61529350724712 2.7770325267451206 1.2497488880002652 0.8616907950223387 0.04559774246630033 0.19236341042805324 58915691.190027215 34698744.623247035 95015094.42507853 0.046590700839866765 2.424970684355488e-12 11.61529350724712 -0.3880580929779265 IHDPQLLTER ddPTM_PC-9_AZD4547_30min_R2 1 IHDPQLLTER 10 0 P14868;P14868-2;H7BZ35 P14868 DARS Aspartate--tRNA ligase, cytoplasmic 0 86.463 0.010458 0.0 14799.0 18272.0 20639.0 25301.0 25636.0 19535.0 18163.0 26655.0 16510.0 23988.0 False True 19504.774161677517 24178.066671565244 20365.313374716956 19468.245346553333 22076.88390957086 18313.473361849025 19779.47181360669 22536.082220965374 17382.684894166967 23148.18742137894 0.8426048142181326 1.044490708124954 0.8797800451498068 0.8410267720820798 0.9537197668090998 0.7911407069797298 0.8544717326480168 0.9735571002052521 0.7509307133962836 1.0 14.498611609727549 -5.4702501277384155 24.98802748998377 0.8764704939097167 0.948194727718249 0.07529847982334015 0.08709566911355077 708.967526798384 336615.33176502894 0.021132260008106637 0.043989811235056936 3.3864905828752197e-06 5.4702501277384155 0.07172423380853232 IHDPQLLTER ddPTM_PC-9_Lapatinib_30min_R1 2 IHDPQLLTER 10 0 P14868;P14868-2;H7BZ35 P14868 DARS Aspartate--tRNA ligase, cytoplasmic 0 ; 92.866 0.0060084 2919000.0 40418.0 45403.0 47592.0 41456.0 42741.0 42720.0 44839.0 41139.0 43115.0 38010.0 False True 39841.63190824657 45297.87214305203 43679.1694704327 44504.81253316195 40227.05841203912 40892.96518518392 47160.54402108799 43050.468125303196 38258.93467892234 44579.97785485858 0.8937113436431283 1.016103513791118 0.9797934313166622 0.9983139219597338 0.9023570748062842 0.917294425724511 1.0578862146282597 0.9656906574845081 0.8582089206837205 1.0 15.44410827948732 IHEAAVQELR ddPTM_PC-9_AZD4547_30min_R2 1 IHEAAVQELR 10 0 Q7Z406;Q7Z406-6;Q7Z406-2;Q7Z406-4;Q7Z406-5;A0A0C4DFM8 Q7Z406 MYH14 Myosin-14 0 65.842 0.044375 0.0 6289.0 7738.3 46950.0 59656.0 49714.0 28848.0 16673.0 51627.0 22539.0 24856.0 False True 8288.77118067369 10239.554144295817 46327.412323414974 45903.230876012225 42812.06922610414 27044.129999622277 18156.86470011916 43649.23342043818 23730.36552571953 23985.79900557758 0.34556994239575867 0.4269006899421922 1.9314517024278468 1.9137670112777163 1.7848923530189158 1.1275059043617235 0.756983942702806 1.8197948465376586 0.9893506370249058 1.0 14.549892878383606 -5.239873283234074 22.242418511195353 1.441935016940686 0.3862335089965843 0.4992889956605633 0.4115969017680406 164.88954303759434 170056.83721166657 0.1099402639172518 0.28988431640328627 5.7560786147565634e-06 5.239873283234074 -1.0557015079441017 IHEGCEEPATHNALAK ddPTM_PC-9_Lapatinib_30min_R1 1 IHEGCEEPATHNALAK 16 0 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 111.72 0.00017985 8737200.0 71222.0 72430.0 69263.0 78243.0 81675.0 78150.0 72400.0 77035.0 76439.0 67637.0 False True 70206.36121948472 72262.29278508599 63568.463502911865 83997.25123099671 76871.03707922815 74807.70667654782 76148.51774407935 80614.32733009405 67829.63488164551 79327.96532936273 0.8850140165324307 0.9109308739365658 0.801337375022556 1.0588605277123586 0.9690282205029004 0.943018094135565 0.9599202176422577 1.0162157442887947 0.8550532539190037 1.0 16.275541925550627 -5.754664928861739 24.998899645125256 0.9706029363560987 0.8702777855883362 0.42671915565461105 0.05620143807527646 156.8007952376474 578615.1425501539 0.014876684833681415 0.025044043072517553 1.7592804277709879e-06 5.754664928861739 -0.1003251507677625 IHEKDPNSATATAPPS(ph)PLKR ddPTM_PC-9_AZD4547_30min_R2 1 IHEKDPNSATATAPPSPLKR 20 2 Q92766;Q92766-2;Q92766-5;Q92766-3;C9JU34;Q92766-6 Q92766 RREB1 Ras-responsive element-binding protein 1 1 IHEKDPNSAT(0.001)AT(0.021)APPS(0.978)PLKR 61.806999999999995 0.0035623000000000004 36960000.0 80177.0 83456.0 118270.0 146540.0 126730.0 133120.0 109610.0 115830.0 98171.0 123810.0 True False 105671.61821479941 110431.51992897055 116701.66252375477 112757.46702043104 109135.72701903243 124795.98535599402 119365.07765729398 97931.13500860696 103360.11863993134 119475.44958483128 0.8844630305389165 0.9243030288876272 0.9767836231567638 0.9437710208436565 0.9134573454067036 1.0445324607662179 0.9990761957546858 0.8196758024256089 0.8651159631464074 1.0 16.86635467087732 -11.42765518759564 0.004109740838321084 1.3355618485082286 0.5557206226339072 0.013316846209921906 0.06545515208599746 672849.8361475476 392.6886315588411 38501.5543458525 36043.174024433625 3.735466211289108e-12 11.42765518759564 -0.7798412258743214 IHEKDPNSATATAPPS(ph)PLKR ddPTM_PC-9_Lapatinib_30min_R1 2 IHEKDPNSATATAPPSPLKR 20 2 Q92766;Q92766-2;Q92766-5;Q92766-3;C9JU34;Q92766-6 Q92766 RREB1 Ras-responsive element-binding protein 1 1 IHEKDPNSATATAPPS(1)PLKR;IHEKDPNSATAT(0.001)APPS(0.999)PLKR 90.545 0.00021437 54064000.0 122164.0 101588.0 110615.0 89200.0 75522.0 111927.0 73914.0 83385.0 100514.0 66574.0 True False 120421.91895786635 101352.77922754812 101520.66168624778 95760.06556247694 71079.94444196475 107140.1431245806 77740.90525602034 87259.37151190852 89193.05486065647 78081.22719572124 1.542264681061075 1.2980428570044573 1.3001929571595028 1.2264159901385936 0.9103333412497883 1.3721626436021457 0.9956414371043653 1.117546107378423 1.1423111298837803 1.0 16.252688107338415 -1.522878745282658 0.4394001801014617 1.0819248201376646 10.635936930303277 0.5666500858466492 0.12174430391788112 61.76808868491197 0.7614391270862223 0.07538976951822036 525.7978891846144 0.02999999999983971 1.522878745282658 9.554012110165612 IHFPLATYAPVISAEK ddPTM_PC-9_AZD4547_30min_R2 2 IHFPLATYAPVISAEK 16 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;Q6PEY2;C9JDS9;P68363;P68363-2;P68366-2;P68366;Q71U36-2;Q71U36 Q9BQE3;P68363;P68366-2;Q71U36-2 TUBA1C;TUBA1B;TUBA3E;TUBA4A;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain;Tubulin alpha-1A chain 0 ; 87.99 0.0034474 23061400.0 123822.0 126906.0 179287.0 228735.0 190903.0 177966.0 158260.0 211373.0 157824.0 171628.0 False True 163194.8203424038 167925.8827179103 176909.5372359551 176003.67967052205 164399.41367564414 166837.7578866046 172344.8334097557 178710.15971833136 166166.25443591797 165619.35595949736 0.985360795523885 1.013926673878487 1.0681694552611276 1.0626999401782735 0.9926340597281905 1.007356639687726 1.0406080401127937 1.0790415086630054 1.0033021410646854 1.0 17.33751176511783 IHFPLATYAPVISAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IHFPLATYAPVISAEK 16 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;Q6PEY2;C9JDS9;P68363;P68363-2;P68366-2;P68366;Q71U36-2;Q71U36 Q9BQE3;P68363;P68366-2;Q71U36-2 TUBA1C;TUBA1B;TUBA3E;TUBA4A;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain;Tubulin alpha-1A chain 0 ;;; 130.47 1.1479000000000001e-05 42117100.0 224113.0 233841.0 246724.0 301898.0 321371.0 286099.0 282178.0 257460.0 258280.0 230984.0 False True 262050.90446648214 257055.18907866997 252606.8358659806 284983.6338265216 258400.65953102676 271095.4647914953 255448.0570481941 250701.94780141924 262056.85638224537 272859.57073166256 0.9603874394576031 0.9420786978055644 0.9257759776892742 1.0444333437245716 0.947009697472349 0.9935347477992548 0.9361887375371143 0.9187947746497274 0.960409252567355 1.0 18.057799122526873 -5.890942424526944 0.0017370751910837962 1.9184184334262997 9.208147347196629e-08 0.02598527313916965 0.03652686878123868 1249344.3457345427 511.01717909007806 279845.7641446177 284524.6265917038 1.285457064809448e-06 5.890942424526944 -1.9184183413448261 IHFPLATYAPVISAEK ddPTM_PC-9_Lapatinib_30min_R1 4 IHFPLATYAPVISAEK 16 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;Q6PEY2;C9JDS9;P68363;P68363-2;P68366-2;P68366;Q71U36-2;Q71U36 Q9BQE3;P68363;P68366-2;Q71U36-2 TUBA1C;TUBA1B;TUBA3E;TUBA4A;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain;Tubulin alpha-1A chain 0 ;;; 136.81 3.7967e-06 50410900.0 248198.0 258973.0 261170.0 232569.0 253974.0 236404.0 246541.0 219606.0 244010.0 241419.0 False True 244658.6510060611 258373.36392975334 239697.6107453539 249672.9000874408 239035.74865209538 226293.55200463973 259305.68664562202 229809.6964711181 216527.02426078718 283147.9524794028 0.8640664672433342 0.9125030277185152 0.846545449636583 0.8817754036402679 0.8442079363773033 0.7992060335350689 0.9157957328491889 0.8116240801276332 0.7647133675689853 1.0 18.11119657177602 -5.73449624626661 1.4532264216986388 0.8480810574316323 0.8852770578751985 0.00902689772708365 0.0640076638655793 1.5466836542991362 6.538924138715518 0.020331778738591554 0.049143611264865356 1.842908417694622e-06 5.73449624626661 0.03719600044356619 IHFS(ph)PSEPK ddPTM_PC-9_AZD4547_30min_R2 2 IHFSPSEPK 9 0 Q8IZT6-2;Q8IZT6 Q8IZT6-2 ASPM Abnormal spindle-like microcephaly-associated protein 1 IHFS(0.997)PS(0.003)EPK;IHFS(1)PSEPK 110.84 0.0012894 5437300.0 59940.0 63289.0 66257.0 83387.0 83915.0 73124.0 56031.0 81597.0 65500.0 75880.0 True False 78999.67317054878 83745.9315661499 65378.38888844525 64163.415466307364 72264.85072833663 68551.5447203404 61017.65045357025 68988.0585625255 68962.19627909982 73223.46429607448 1.0788846707814663 1.1437034886457773 0.8928611820944696 0.8762685033156397 0.9869083827574484 0.9361964143509591 0.8333073426688637 0.942157807278506 0.9418046106130067 1.0 16.160018410560603 -5.262121040430462 24.99998416402755 0.9215482535385354 1.1112940912249252 0.6927681580446603 0.049230756493215726 29.83615784304312 1094291.5896251083 0.012709304860708762 0.02926880979903051 5.468635275660327e-06 5.262121040430462 0.18974583768638975 IHFS(ph)PSEPK ddPTM_PC-9_Lapatinib_30min_R1 1 IHFSPSEPK 9 0 Q8IZT6-2;Q8IZT6 Q8IZT6-2 ASPM Abnormal spindle-like microcephaly-associated protein 1 IHFS(0.994)PS(0.006)EPK 120.06 0.0009632999999999999 3039900.0 57247.0 46404.0 51510.0 42469.0 48697.0 45898.0 42983.0 37671.0 45266.0 28902.0 True False 56430.64728218597 46296.55438905328 47275.04663435004 45592.31193243093 45832.738201985645 43935.04953346373 45208.44942256575 39421.33218474675 40167.66640788818 33897.67219050574 1.6647351760629567 1.36577385399403 1.3946399141705992 1.3449983136364358 1.3520910210118424 1.2961081600691542 1.3336741581691263 1.1629510121874418 1.1849682828409254 1.0 15.048898584046126 -1.522878745281636 0.09301241579678222 0.7877270304262363 2.9176173997143984 0.8381819202369065 0.06649181338761068 56.913640826605906 0.380479217015437 1.093353308796182 15.455469380298538 0.029999999999910314 1.522878745281636 2.1298903692881623 IHGVGFK ddPTM_PC-9_AZD4547_30min_R2 1 IHGVGFK 7 0 H7C2W9;C9JU56;B7Z4E3;B7Z4C8;P62899-3;P62899;P62899-2;B8ZZK4 H7C2W9 RPL31 60S ribosomal protein L31 0 74.335 0.026694 0.0 57729.0 64541.0 79222.0 92416.0 87098.0 79546.0 66431.0 81030.0 68452.0 80409.0 False True 76085.62116220572 85402.61608195554 78171.46451726467 71110.91901296677 75005.94612091596 74571.97604513132 72343.2303061005 68508.6753841614 72070.23297247228 77593.90538459497 0.9805618209972365 1.1006356189787925 1.0074433569209724 0.9164497992529799 0.9666473900127625 0.9610545528738962 0.9323313467408368 0.8829130979372344 0.9288130635422389 1.0 16.24365571989069 -5.602434820801952 4.781692472847716 0.9382002449041515 1.043802067172598 0.5123065983109933 0.04016816722601193 0.1433773746887553 5.914485186648062 0.010815297567270933 0.0194161266605885 2.497843238960985e-06 5.602434820801952 0.1056018222684465 IHGVGFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IHGVGFK 7 0 H7C2W9;C9JU56;B7Z4E3;B7Z4C8;P62899-3;P62899;P62899-2;B8ZZK4 H7C2W9 RPL31 60S ribosomal protein L31 0 72.82300000000001 0.031772 3226800.0 43968.0 49424.0 47288.0 58715.0 56690.0 47129.0 49277.0 46783.0 45997.0 39601.0 False True 51410.91399241583 54330.48808816313 48415.52526073867 55425.38890659836 45582.00145257008 44657.47227413716 44609.12582541472 45554.995820685835 46669.61910722532 46780.34781865648 1.0989852874055082 1.1613955565010907 1.0349543669153751 1.1848007013854256 0.9743835515988086 0.9546203556940486 0.9535868779415988 0.973806265769534 0.9976330079489704 1.0 15.513614967926095 -6.2801414769166914 24.543788139196185 0.9722051669586672 1.1169112567823718 0.7605952668282895 0.039633832387121315 289.579624914147 380030.3336641215 0.01158307760697877 0.013156932609879693 5.246365254299578e-07 6.2801414769166914 0.1447060898237046 IHGVGFK ddPTM_PC-9_Lapatinib_30min_R1 1 IHGVGFK 7 0 H7C2W9;C9JU56;B7Z4E3;B7Z4C8;P62899-3;P62899;P62899-2;B8ZZK4 H7C2W9 RPL31 60S ribosomal protein L31 0 91.584 0.012723 7154200.0 115070.0 112430.0 118880.0 113150.0 118530.0 109600.0 115280.0 110440.0 107460.0 100940.0 False True 113429.08069874639 112169.67524267836 109106.14529007029 121471.42845733468 111558.29843894615 104912.66349007867 121248.6343306278 115571.4455810421 95356.72319603387 118387.34450590464 0.9581182952633003 0.9474802877860297 0.9216031134529633 1.0260507908535461 0.9423160803592661 0.8861814067030289 1.0241688825496078 0.9762145275188423 0.8054638238065885 1.0 16.853155340923784 IHIDLPNEQAR ddPTM_PC-9_AZD4547_30min_R2 1 IHIDLPNEQAR 11 0 P62333;A0A087X2I1 P62333 PSMC6 26S protease regulatory subunit 10B 0 139.31 9.226799999999999e-05 2919600.0 6210.7 4467.7 8966.1 11846.0 9081.2 8145.1 6538.1 8044.1 6959.5 6347.2 False True 8185.573409414866 5911.796654364713 8847.203655654337 9115.087718875568 7820.432132922249 7635.785609398337 7119.978234022015 6801.069180028798 7327.364961899159 6124.986459937318 1.3364231028028486 0.9651934241868043 1.444444606289771 1.488180876561293 1.2768080687320054 1.2466616309020349 1.1624479956964477 1.110381096270766 1.196307128158802 1.0 12.580490939519683 -7.254045143157649 1.8607923850939745 1.1133053697243418 1.3005911657329927 0.2934085717976036 0.13784980333937008 0.5409197005014456 3.656423696930848 0.07651857377000597 0.04821085968998705 5.57127834733352e-08 7.254045143157649 0.18728579600865092 IHIDLPNEQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IHIDLPNEQAR 11 0 P62333;A0A087X2I1 P62333 PSMC6 26S protease regulatory subunit 10B 0 99.34299999999999 0.0038618000000000003 2382600.0 4328.0 4963.9 4801.5 8443.5 9197.4 6157.9 9331.1 5325.6 6634.6 6248.8 False True 5060.644918103527 5456.683186727766 4915.985969790152 7970.438069196342 7395.235494088334 5834.968883636597 8447.190656686233 5185.808642939627 6731.61847356995 7381.65797452642 0.6855702249504725 0.7392218937206783 0.6659731440761509 1.0797625813471392 1.0018393590720092 0.790468605260859 1.1443486931847684 0.7025262699566258 0.9119385504991276 1.0 12.8497291772326 -5.744817356247667 24.999233704361643 0.9388264700524079 0.7011516771325836 0.46413777663823574 0.12301045685634691 226.70048464942087 340950.8465114982 0.03295333945687719 0.056876184478053815 1.7996275943962476e-06 5.744817356247667 -0.2376747929198243 IHIDLPNEQAR ddPTM_PC-9_Lapatinib_30min_R1 2 IHIDLPNEQAR 11 0 P62333;A0A087X2I1 P62333 PSMC6 26S protease regulatory subunit 10B 0 ; 144.55 0.00015106 7157700.0 14843.7 14876.8 15788.3 16735.4 17999.699999999997 17284.4 14045.8 15555.7 13564.8 15361.5 False True 14632.026115998806 14842.35368362787 14490.24691860045 17966.177143657835 16940.99303477177 16545.18650390434 14773.022797372776 16278.474610874806 12036.989380323452 18016.714807087883 0.8121361897920746 0.823810214156734 0.8042668751630514 0.9971949567958879 0.9402931231451298 0.9183242717143619 0.8199620716403293 0.9035206909347734 0.6681012331719892 1.0 14.13704835165524 IHIDPEIQDGS(ph)PTTSR ddPTM_PC-9_AZD4547_30min_R2 6 IHIDPEIQDGSPTTSR 16 0 P50479;P50479-2;C9J542 P50479 PDLIM4 PDZ and LIM domain protein 4 1 IHIDPEIQDGS(0.597)PT(0.05)T(0.014)S(0.338)R;IHIDPEIQDGS(0.566)PT(0.06)T(0.02)S(0.354)R;IHIDPEIQDGS(0.7)PT(0.249)T(0.014)S(0.037)R;IHIDPEIQDGS(0.97)PT(0.02)T(0.006)S(0.003)R;IHIDPEIQDGS(0.904)PT(0.054)T(0.017)S(0.025)R;IHIDPEIQDGS(0.961)PT(0.025)T(0.008)S(0.005)R 156.29 1.4802999999999999e-05 247334800.0 278189.91000000003 302940.95 489441.2 546144.2 525481.4 443433.7 385882.1 491257.8 402368.6 425281.9 True False 366648.51467041037 400860.68775434024 482950.8898928016 420239.09253377665 452527.37807921425 415705.7206396794 420224.85934731923 415345.1949912043 423636.98274422274 410392.91012673517 0.8934085010318139 0.9767729360396328 1.176801250644558 1.023992087007548 1.1026686058964015 1.012945668362798 1.02395740515485 1.012067179384117 1.032271689619096 1.0 18.646646281859965 -5.004998843106024 12.576647135248505 1.0494450874338455 0.914153180336106 0.47193499946362794 0.05123401857499555 0.2891949656957376 745.2344693594719 0.012763180360397374 0.041897846296128353 9.885557280144678e-06 5.004998843106024 -0.13529190709773942 IHIDPEIQDGS(ph)PTTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 12 IHIDPEIQDGSPTTSR 16 0 P50479;P50479-2;C9J542 P50479 PDLIM4 PDZ and LIM domain protein 4 1 IHIDPEIQDGS(0.37)PT(0.13)T(0.13)S(0.37)R;IHIDPEIQDGS(0.983)PT(0.013)T(0.003)SR;IHIDPEIQDGS(0.56)PT(0.147)T(0.147)S(0.147)R;IHIDPEIQDGS(0.993)PT(0.005)T(0.002)SR;IHIDPEIQDGS(0.992)PT(0.003)T(0.003)S(0.002)R;IHIDPEIQDGS(0.415)PT(0.25)T(0.085)S(0.25)R;IHIDPEIQDGS(0.959)PT(0.03)T(0.01)S(0.001)R;IHIDPEIQDGS(0.708)PT(0.114)T(0.114)S(0.064)R;IHIDPEIQDGS(0.368)PT(0.238)T(0.238)S(0.156)R;IHIDPEIQDGS(0.983)PT(0.013)T(0.004)S(0.001)R;IHIDPEIQDGS(0.929)PT(0.021)T(0.007)S(0.043)R;IHIDPEIQDGS(0.602)PT(0.092)T(0.082)S(0.225)R 168.55 2.6276e-05 751200500.0 759023.1000000001 763248.4 940142.1000000001 969446.9 1049735.6 803566.8 929866.0 739524.8999999999 761415.3 635322.4 True False 887510.7194404298 839018.6570190507 962558.6531727671 915131.9331822546 844047.4447700562 761426.3424094963 841782.3608331486 720113.1549664015 772549.5583062755 750501.321910649 1.1825571701605777 1.1179442760780909 1.2825542408403174 1.2193608544918801 1.124644847555038 1.0145569636986569 1.1216267530217183 0.9595095091013507 1.029378011406423 1.0 19.517495087405038 -6.56403728960161 3.0593701841716996 1.0280508127653865 1.1997919562766095 0.7023209780145291 0.05388459416646495 0.15208261371879256 2.9174442223720205 0.019258436455507583 0.019974473414108004 2.728743476064808e-07 6.56403728960161 0.17174114351122305 IHIDPEIQDGS(ph)PTTSR ddPTM_PC-9_Lapatinib_30min_R1 8 IHIDPEIQDGSPTTSR 16 0 P50479;P50479-2;C9J542 P50479 PDLIM4 PDZ and LIM domain protein 4 1 IHIDPEIQDGS(0.532)PT(0.146)T(0.177)S(0.146)R;IHIDPEIQDGS(0.58)PT(0.181)T(0.058)S(0.181)R;IHIDPEIQDGS(0.766)PT(0.078)T(0.078)S(0.078)R;IHIDPEIQDGS(0.318)PT(0.296)T(0.089)S(0.296)R;IHIDPEIQDGS(0.979)PT(0.012)T(0.004)S(0.006)R;IHIDPEIQDGS(0.983)PT(0.013)TS(0.004)R;IHIDPEIQDGS(0.948)PT(0.032)T(0.01)S(0.01)R;IHIDPEIQDGS(0.857)PT(0.063)T(0.017)S(0.063)R 208.62 2.0095e-17 1072605000.0 831468.0 889866.0 977553.0 868764.0 833902.0 841222.0 762008.0 696602.0 810796.0 626749.0 True False 819611.1138474438 887805.5699502036 897182.3658037022 932655.8026717476 784853.5238744115 805244.8960442594 801461.0457062203 728968.6719906288 719475.6164196103 735081.7295594504 1.114993178158099 1.207764435231282 1.2205205621712323 1.2687783754749387 1.0677091979211486 1.095449476790641 1.0903019534801286 0.9916838396017742 0.9787695537621468 1.0 19.48754513836534 -7.03261690217996 0.9311466193467062 0.9883111398395311 1.2005529619418163 0.7248584097820814 0.05039581616883958 0.30919501543984573 0.5513917742918586 0.03626792825281692 0.025524788421740847 9.276477548763846e-08 7.03261690217996 0.21224182210228515 IHIDPEIQDGSPTTS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 IHIDPEIQDGSPTTSR 16 0 P50479;P50479-2;C9J542 P50479 PDLIM4 PDZ and LIM domain protein 4 1 IHIDPEIQDGS(0.358)PT(0.097)T(0.03)S(0.514)R 122.13 3.5931e-05 433450000.0 256190.0 292980.0 401400.0 487700.0 488110.0 434390.0 386480.0 497780.0 366520.0 401680.0 True False 337653.0909169656 387680.0554638348 396077.1737298993 375268.29988988844 420344.3518918961 407227.52463033627 420875.9712890337 420859.53884645045 385893.49893459014 387617.30546187644 0.8710991128598489 1.000161886482038 1.0218253110705215 0.9681412429270329 1.0844313346408072 1.0505917018980686 1.0858028404782571 1.0857604470083277 0.9955528132954945 1.0 18.56427345681699 -3.59649378600461 0.778589771187026 1.049840020786261 3.289384819382576e-14 0.6168796346790237 0.03907975210379591 9.07487651389125 1.0210584858548257 0.014403038676350389 12.64587176923713 0.00025322478670651506 3.59649378600461 -1.0498400207862282 IHIDPEIQDGSPTTS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IHIDPEIQDGSPTTSR 16 0 P50479;P50479-2;C9J542 P50479 PDLIM4 PDZ and LIM domain protein 4 1 IHIDPEIQDGS(0.075)PT(0.016)T(0.025)S(0.884)R 115.57 9.8635e-05 88994000.0 15061.0 18877.0 20522.0 18380.0 21811.0 19658.0 17560.0 15395.0 17151.0 13469.0 True False 17610.52983169067 20750.983806253156 21011.322310118394 17350.228188763995 17537.291121573577 18627.099874068794 15896.589676609416 14990.89756235082 17401.800928495806 15910.823079454663 1.1068270788851147 1.3042055525743668 1.320567905581824 1.0904670425986953 1.102224004000091 1.1707188107774014 0.9991054263645464 0.9421824054915345 1.093708404750375 1.0 13.957720848903705 -6.589196199633062 0.8686486483037905 1.0046505048423566 1.2405069030642146 0.5244278213933677 0.08128398834121876 0.4698683640396635 0.7801734172838813 0.04933576223851207 0.05560083444613644 2.5751575246609305e-07 6.589196199633062 0.235856398221858 IHIDPEIQDGSPTTS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 IHIDPEIQDGSPTTSR 16 0 P50479;P50479-2;C9J542 P50479 PDLIM4 PDZ and LIM domain protein 4 1 IHIDPEIQDGS(0.237)PT(0.039)T(0.039)S(0.685)R 73.688 0.0079878 2931300.0 17946.0 16699.0 17822.0 12397.0 16275.0 15897.0 12253.0 13607.0 14930.0 14039.0 True False 17690.086749106656 16660.33449148351 16356.743954909472 13308.716735179678 15317.736497881104 15217.12236771697 12887.400385610543 14239.230894795703 13248.426180130127 16465.62244420837 1.0743648962586885 1.0118253681532476 0.9933875266684987 0.808272920156802 0.9302859062743162 0.9241753489294571 0.7826852844025685 0.8647854609228102 0.8046113182189562 1.0 14.007169430213295 -5.614110349433358 5.0270096837321985 0.8689475269885572 1.0342268278442484 0.5470964651030469 0.06450364934879288 0.1470206049139921 6.17983066448838 0.017373732522167788 0.030893465436538113 2.4315860913923395e-06 5.614110349433358 0.1652793008556912 IHLDEK ddPTM_PC-9_AZD4547_30min_R2 3 IHLDEK 6 0 P37837 P37837 TALDO1 Transaldolase 0 ;; 127.66 0.009325299999999998 17495900.0 275899.0 274357.0 326876.0 446995.0 389214.0 353707.0 306236.0 391848.0 297656.0 340763.0 False True 363629.1429442977 363037.53490644816 322541.4106630161 343947.2087539076 335178.35442267475 331589.6453749441 333490.4107422589 331296.89537125634 313389.4884832326 328832.9910901852 1.1058170949902328 1.1040179809904842 0.9808669428018444 1.0459632034292363 1.0192966141002235 1.0083831439042041 1.0141634804848287 1.0074928743399576 0.9530354221583653 1.0 18.3269955231356 -1.5228787452835244 0.43791769745163156 0.9938333279499358 3.642904697199213 0.6533904947179989 0.027416930538955078 50.56038387472246 0.6252364921169329 0.017450196756603344 118.8151568870074 0.029999999999779862 1.5228787452835244 2.6490713692492776 IHLDEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IHLDEK 6 0 P37837 P37837 TALDO1 Transaldolase 0 ; 103.29 0.028935000000000002 20681000.0 183293.0 200198.0 169476.0 221270.0 236508.0 196669.0 218217.0 182550.0 176240.0 183366.0 False True 214320.88469823278 220072.33437751082 173516.95058130872 208872.95926701927 190165.95518688357 186355.33142401226 197545.90600573312 177758.25592771344 178817.17658667703 216608.8042755429 0.989437550403539 1.015989793736925 0.801061393426012 0.9642865624303846 0.877923479716817 0.8603312873051737 0.9119938899364389 0.8206418779801369 0.8255305096426642 1.0 17.72473235831805 -5.240903552689104 24.750544277009233 0.879303002343689 1.0027137061188953 0.38906668477397266 0.06002280247958184 681.6181792010799 821508.3837091057 0.014517217039206061 0.03830656410993648 5.742439750819739e-06 5.240903552689104 0.12341070377520635 IHLDEK ddPTM_PC-9_Lapatinib_30min_R1 1 IHLDEK 6 0 P37837 P37837 TALDO1 Transaldolase 0 127.66 0.009325299999999998 14124000.0 104550.0 96468.0 99340.0 88320.0 92316.0 85968.0 84067.0 83521.0 81353.0 73612.0 False True 103059.09782787817 96244.63427297636 91172.64866348909 94815.34742688322 86886.15438023905 82291.34904119588 88419.57791700981 87401.69056840101 72190.1684549315 86335.73611817541 1.1937015013900154 1.1147716878354723 1.0560244547946283 1.0982167024915501 1.0063753236702613 0.9531551214036836 1.0241364919386575 1.0123466191191852 0.8361562859221862 1.0 16.39767022341364 -4.644989214959141 0.390101683746185 0.9465579698448078 1.384317944081607 0.6701969109105297 0.052820865755622955 3.9947681730988864 0.4439946745300616 0.044549821902380715 0.8406373312340641 2.2647005472776026e-05 4.644989214959141 0.43775997423679913 IHLGS(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 1 IHLGSSPK 8 0 Q5JW53;Q9H410-4;Q9H410 Q5JW53 DSN1 Kinetochore-associated protein DSN1 homolog 1 IHLGS(0.921)S(0.079)PK 117.53 0.0020078 7449100.0 71674.0 77272.0 97559.0 128040.0 127920.0 118100.0 104560.0 100780.0 96959.0 119850.0 True False 94464.84108818688 102248.6628636816 96265.30391608183 98522.35619828023 110160.51605992756 110715.18833040011 113865.63744044001 85206.76669401217 102084.05479427826 115654.0879795006 0.8167877395300591 0.8840903477774597 0.8323553935520602 0.8518709361639086 0.9524999763039351 0.9572959353587579 0.9845362099143647 0.7367380451706546 0.8826670684772716 1.0 16.81945673568562 -6.156191778007817 8.081979349280257 0.910918592371618 0.8474904907843062 0.19460567109562377 0.07133733749820732 0.6328429472510732 43.75115567996781 0.022297239245123796 0.028849154035923596 6.979241430607218e-07 6.156191778007817 -0.06342810158731182 IHLGS(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IHLGSSPK 8 0 Q5JW53;Q9H410-4;Q9H410 Q5JW53 DSN1 Kinetochore-associated protein DSN1 homolog 1 IHLGS(0.638)S(0.362)PK 106.88 0.0021643 25900000.0 250090.0 234600.0 226230.0 357840.0 343910.0 284550.0 321870.0 315610.0 287370.0 238010.0 True False 292425.29749734583 257889.53758261347 231624.1811820522 337791.3849329333 276523.3042785921 269627.6970783536 291380.14346299914 307325.57191643695 291572.2425993727 281159.32891387626 1.040069695097759 0.9172362822846589 0.8238182317365059 1.2014233574885378 0.9835110410414152 0.9589854198326992 1.0363523934582077 1.0930655337087387 1.0370356328766388 1.0 18.10102839097408 -5.742546638601837 24.999866975963084 1.0417931661640185 0.9260609673596519 0.3117097733441696 0.07980790647378498 309.67526981375215 409775.4943774828 0.021849834743266194 0.03776539068170025 1.8090616258710376e-06 5.742546638601837 -0.11573219880436658 IHLGS(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 1 IHLGSSPK 8 0 Q5JW53;Q9H410-4;Q9H410 Q5JW53 DSN1 Kinetochore-associated protein DSN1 homolog 1 IHLGS(0.748)S(0.252)PK 86.67 0.0069715 57796000.0 118790.0 84258.0 106980.0 100600.0 107410.0 100260.0 87433.0 86654.0 105150.0 83430.0 True False 117096.03281658185 84062.90577779614 98184.51735474229 107998.4595917622 101092.35497618504 95972.11351747523 91959.85292704534 90680.2611859799 93306.89972141208 97850.7643365128 1.1966797971437788 0.8590929907169693 1.003410837109884 1.1037058353509746 1.0331279031048166 0.980800856980771 0.9397969811537866 0.926720008789372 0.9535633201650404 1.0 16.578295499693198 -6.927585129266869 3.4619946404073962 0.9496810485089712 1.0306564258669868 0.19060803181408803 0.08142816688141422 0.435454413560235 10.495744810132482 0.030473081833938823 0.02608618649890559 1.1814487053651512e-07 6.927585129266869 0.08097537735801563 IHLGSS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 IHLGSSPK 8 0 Q5JW53;Q9H410-4;Q9H410 Q5JW53 DSN1 Kinetochore-associated protein DSN1 homolog 1 IHLGS(0.223)S(0.777)PK;IHLGS(0.111)S(0.889)PK;IHLGS(0.045)S(0.955)PK 109.44 0.0021411 126924700.0 175739.0 151967.0 219807.0 295705.0 243164.0 240951.0 203698.0 238990.0 198754.0 248148.0 True False 231620.34640172 201087.36087334462 216892.2155606577 227534.780846708 209404.8759161677 225884.29587974862 221826.72738468577 202059.58694385763 209259.73067566715 239460.41405037287 0.9672594416920884 0.8397519968834761 0.9057539486047672 0.9501978928293501 0.8744864020493897 0.9433053758615468 0.9263607442774333 0.8438120669972299 0.8738802674568469 1.0 17.869427653682152 -4.377186687662891 14.627872515512903 0.9036333108158567 9.57405178127474 0.12459274368571349 0.04789978645025886 249307.87064054536 57756.44389829429 0.8950093701731524 72106334.17401375 4.195785833953881e-05 4.377186687662891 8.670418470458884 IHLGSS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IHLGSSPK 8 0 Q5JW53;Q9H410-4;Q9H410 Q5JW53 DSN1 Kinetochore-associated protein DSN1 homolog 1 IHLGS(0.205)S(0.795)PK;IHLGS(0.183)S(0.817)PK;IHLGS(0.178)S(0.822)PK;IHLGS(0.485)S(0.515)PK 106.88 0.0021643 79918000.0 389444.0 454437.0 428135.0 544557.0 556540.0 509442.0 592475.0 524711.0 483552.0 393971.0 True False 455369.1773303846 499550.5020904938 438343.3621110293 514047.2367676152 447489.9821558184 482725.9646986142 536351.4788524592 510937.8922272592 490623.03320949327 465394.8236272796 0.9784577614792634 1.0733907571145838 0.9418741676037312 1.104540082249174 0.9615276308148183 1.037239651563496 1.1524655015974279 1.0978589925969044 1.0542081869015762 1.0 18.828095638835457 -7.0137479838085905 24.521456084383832 1.0857973055864985 1.0148971724792675 0.2049885740041162 0.05823661333404499 697.731257131692 1244499.3804643785 0.020317000619584667 0.01644049499481694 9.688399000424835e-08 7.0137479838085905 -0.07090013310723098 IHLGSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 IHLGSSPK 8 0 Q5JW53;Q9H410-4;Q9H410 Q5JW53 DSN1 Kinetochore-associated protein DSN1 homolog 1 IHLGS(0.225)S(0.775)PK;IHLGS(0.067)S(0.933)PK;IHLGS(0.184)S(0.816)PK 104.05 0.0038644 56580600.0 319533.0 255025.0 289931.0 266344.0 301794.0 284392.0 239565.0 264862.0 275815.0 212767.0 True False 314976.4008248241 254434.50528118905 266093.9923460244 285931.82625753724 284043.0702698326 272229.2171101319 251968.50349945272 277168.45544626896 244749.81023928968 249543.49245579317 1.2622104376479482 1.0195998412030813 1.0663231075567443 1.1458196062082857 1.1382507613182944 1.0909089010139488 1.0097177891508797 1.1107019971493328 0.9807901934475303 1.0 17.928931756460273 -7.685994682897875 0.6814152455604722 0.9955244404830949 1.1221295862639071 0.3372359546179313 0.06661030339936522 0.9290255126588223 0.8455285077655382 0.06130711082812006 0.032068477091973836 2.0606551418815033e-08 7.685994682897875 0.12660514578081228 IHLPLNYPPGS(ph)PDLGR ddPTM_PC-9_AZD4547_30min_R2 1 IHLPLNYPPGSPDLGR 16 0 Q08174-2;Q08174 Q08174-2 PCDH1 Protocadherin-1 1 IHLPLNYPPGS(1)PDLGR 102.07 0.00087972 11844000.0 42157.0 69927.0 96565.0 148390.0 93124.0 61861.0 60705.0 111520.0 55795.0 63461.0 True False 55562.04907992701 92529.53525298505 95284.48500554994 114180.97810264622 80195.34003724746 57992.82189082893 66107.62739883248 94287.14647465986 58744.20979224995 61239.24970602509 0.9072947390219328 1.510951484500004 1.5559381518055286 1.8645064831911615 1.309541518261896 0.946987792456955 1.079497670467514 1.5396522153239791 0.9592575035495633 1.0 15.902168986815175 -6.522684947823553 24.999192151897926 1.136214666288818 1.4848131391452546 0.27154343734397435 0.2711254828748786 9.874365985138697 1273995.2215052664 0.09085111876637188 0.09178301173070592 3.0013390041382847e-07 6.522684947823553 0.34859847285643664 IHLPLNYPPGS(ph)PDLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IHLPLNYPPGSPDLGR 16 0 Q08174-2;Q08174 Q08174-2 PCDH1 Protocadherin-1 1 IHLPLNYPPGS(1)PDLGR;IHLPLNYPPGS(1)PDLGR;IHLPLNYPPGS(1)PDLGR 123.43 2.3486999999999997e-05 25174000.0 101854.0 110180.0 143795.0 100350.0 218161.0 113899.0 106467.0 110764.0 113335.0 92716.0 True False 119095.87049180146 121117.94224574762 147223.6181455744 94727.7148390895 175413.91813184263 107925.93593226989 96381.67500567071 107856.56236415888 114992.30996624539 109524.67686054781 1.0873884671984941 1.10585071526813 1.3442049989613458 0.864898373173942 1.6015926561937108 0.9854029158167386 0.8799996290186601 0.9847695099935071 1.0499214721506025 1.0 16.740896432604885 -6.9534418457903415 24.999972979481196 0.9710141857119466 1.1956877993801096 0.26819607331943507 0.1820924488575931 162.4779852355427 87244.00648698684 0.06116577640837079 0.053943125291237314 1.1131614407232504e-07 6.9534418457903415 0.22467361366816296 IHLPLNYPPGS(ph)PDLGR ddPTM_PC-9_Lapatinib_30min_R1 3 IHLPLNYPPGSPDLGR 16 0 Q08174-2;Q08174 Q08174-2 PCDH1 Protocadherin-1 1 IHLPLNYPPGS(1)PDLGR;IHLPLNYPPGS(1)PDLGR;IHLPLNYPPGS(1)PDLGR 103.73 0.00075069 21822700.0 126507.0 132994.0 61846.4 40203.6 70747.3 44403.9 35594.3 33655.4 77538.0 22558.0 True False 124702.98698145778 132686.0605641272 56761.62772600787 43160.30685927805 66586.08290854348 42504.848707546545 37437.1986897525 35219.15274907822 68804.85392866243 26457.12024335438 4.713399864929792 5.015136165375212 2.1454197283721954 1.6313304873049912 2.5167547448883396 1.606556129940979 1.4150141188989056 1.3311786175188407 2.6006176521023727 1.0 14.69136841785802 -5.301201231197893 4.580078372312646 1.7707093585084248 4.894557016722003 0.8688374205901426 0.48049682761696016 0.05925405156510938 2.946644300995024 0.12453269003503353 0.2887371691810845 4.998028966660495e-06 5.301201231197893 3.1238476582135783 IHMS(ph)GPK ddPTM_PC-9_AZD4547_30min_R2 1 IHMSGPK 7 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 IHMS(1)GPK 72.23 0.027306 12253000.0 29819.0 34675.0 37930.0 50342.0 57508.0 61358.0 50822.0 51408.0 47870.0 49045.0 True False 39300.8217262695 45883.01564341751 37427.02341697827 38736.429676146734 49524.00686033706 57521.2745603447 55345.059544740376 43464.07483831886 50400.31047145808 47327.94947813619 0.8303935023516088 0.9694697562296422 0.7908017108213871 0.8184683702394834 1.046400856289271 1.2153764360088632 1.1693948323349146 0.9183595595747858 1.0649164188856568 1.0 15.53040479704495 -6.3243887983057965 5.585349643126192 1.0792780486576632 0.8564357568495975 0.5883596868512699 0.08876669021138614 0.1645410739632386 10.430216379093048 0.029621893847325064 0.03391520359643972 4.7381761428980837e-07 6.3243887983057965 -0.2228422918080657 IHMS(ph)GPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IHMSGPK 7 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 IHMS(1)GPK 88.819 0.011798000000000001 4122000.0 45218.0 43285.0 50225.0 57314.0 70841.0 50084.0 48216.0 50339.0 43893.0 39100.0 True False 52872.51430379045 47582.04873940077 51422.5544793732 54102.8823944951 56960.21458637356 47457.506872156955 43648.63142638949 49017.654588579266 44534.85208760225 46188.52048457029 1.144711147902064 1.0301704458209697 1.1133189359583706 1.1713491107074685 1.233211499065047 1.027474064427125 0.9450103828497977 1.0612518884417195 0.9641974157297274 1.0 15.495246713920874 -6.95045239315808 10.638259003581057 0.996077776356362 1.1328249255480185 0.6164622924728338 0.05523528133590746 0.38095179252837974 79.87764608556449 0.020631496785591407 0.018188360394270214 1.1208502856710395e-07 6.95045239315808 0.13674714919165654 IHNVGS(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 4 IHNVGSPLK 9 0 P52701-2;P52701;P52701-3;A0A087WWJ1;A0A494C0M1;P52701-4 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 IHNVGS(1)PLK;IHNVGS(1)PLK;IHNVGS(1)PLK;IHNVGS(1)PLK 110.98 0.0012840999999999998 59885500.0 291537.0 274795.0 296639.0 304185.0 311520.0 331622.0 329384.0 362655.0 302117.0 330349.0 True False 384239.7016536916 363617.1098408914 292705.37303952064 234059.84786140162 268270.82522661594 310885.62391620653 358698.53789864114 306615.0027328537 318086.2878359206 318783.58206040994 1.2053308993211502 1.1406393876708036 0.9181946295592242 0.7342280501040576 0.8415453000831713 0.9752247023100872 1.125210199283937 0.9618280864751363 0.997812640726406 1.0 18.28221780423585 -5.181374681267761 4.361436206291971 0.9393028032676813 1.1873718071209722 0.4676463238581181 0.09819594423694285 0.21487022663480757 7.485296063362375 0.02899991209861322 0.08408851078969434 6.586054477682211e-06 5.181374681267761 0.2480690038532909 IHNVGS(ph)PLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IHNVGSPLK 9 0 P52701-2;P52701;P52701-3;A0A087WWJ1;A0A494C0M1;P52701-4 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 IHNVGS(1)PLK;IHNVGS(1)PLK;IHNVGS(1)PLK;IHNVGS(1)PLK 114.86 0.0020136 47897300.0 312415.0 349085.0 317380.0 368172.0 362094.0 268845.0 356565.0 340298.0 286436.0 252403.0 True False 365300.6890224836 383739.85177760606 324947.542870353 347544.5164697282 291144.2800135281 254746.2949254263 322788.5818929523 331365.53807553416 290624.5846163268 298161.66587895155 1.2251765764241112 1.2870194115879328 1.0898367565543319 1.1656244119954213 0.9764644933655812 0.854389829673305 1.082595849273256 1.111361975721127 0.9747214946616085 1.0 18.18573525921652 -5.697552572123505 1.382151709296401 1.006943321900371 1.2557706336067216 0.5921369229151274 0.07856780457718963 0.3408845947933491 1.2837304649646495 0.02778586201483035 0.07312959808378208 2.0065381802819648e-06 5.697552572123505 0.24882731170635064 IHNVGS(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 2 IHNVGSPLK 9 0 P52701-2;P52701;P52701-3;A0A087WWJ1;A0A494C0M1;P52701-4 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 IHNVGS(1)PLK;IHNVGS(1)PLK 92.611 0.0067512 14557700.0 81554.0 108398.0 100870.0 114174.0 128500.0 117496.0 108850.0 110176.0 110059.0 92673.0 True False 80391.02500482819 108147.01109095324 92576.8579694602 122570.73683329887 120941.88264072017 112470.9699765535 114485.72039285948 115295.17917726262 97662.9964473504 108691.40457098969 0.7396263331229872 0.9949913842572446 0.8517403775842772 1.127694846865689 1.1127088026701257 1.034773360602726 1.0533097887982978 1.0607571006404632 0.8985346802061399 1.0 16.729878329492742 -4.083615879748457 0.9796242120506106 1.037366395421497 1.1455358240480562e-09 0.5125438207248068 0.08120032578639887 5.349823272143428 1.5441193630980825 0.026311869834972072 8.13987366964354 8.248673625442697e-05 4.083615879748457 -1.037366394275961 IHPMAYQLQLQAAS(ph)NFKSPVK ddPTM_PC-9_AZD4547_30min_R2 2 IHPMAYQLQLQAASNFKSPVK 21 1 Q5SRQ6;P67870 Q5SRQ6 CSNK2B Casein kinase II subunit beta 1 IHPMAYQLQLQAAS(0.5)NFKS(0.5)PVK;IHPMAYQLQLQAAS(0.614)NFKS(0.386)PVK 56.247 0.0076006 234460000.0 187971.0 156895.0 212508.0 273990.0 269993.0 202645.0 217098.0 231330.0 190578.0 229034.0 True False 247741.86796031377 207608.24050105247 209690.0050697395 210825.8386033022 232509.13236841754 189973.57611527474 236419.30142544644 195583.26393456807 200651.5640073016 221015.5893725245 1.12092485721784 0.9393375421637169 0.9487566269196713 0.9538957826542844 1.0520033135604772 0.859548309033857 1.0696951382328004 0.8849297214275237 0.9078615883022665 1.0 17.75378860838483 -4.757723355744662 24.930302564356 0.9567785238777277 1.1209250996018079 0.36962064375141346 0.06408720943874391 109.2669112800685 732945.2680961962 0.015043672688477935 0.10937270227762108 1.746934590558982e-05 4.757723355744662 0.1641465757240802 IHPMAYQLQLQAAS(ph)NFKSPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IHPMAYQLQLQAASNFKSPVK 21 1 Q5SRQ6;P67870 Q5SRQ6 CSNK2B Casein kinase II subunit beta 1 IHPMAYQLQLQAAS(0.5)NFKS(0.5)PVK;IHPMAYQLQLQAAS(0.5)NFKS(0.5)PVK;IHPMAYQLQLQAAS(0.635)NFKS(0.365)PVK 63.336999999999996 0.0024525 118051800.0 238660.0 205699.0 186197.0 312877.0 292993.0 290598.0 298964.0 342185.0 273484.0 217469.0 True False 279060.4242501354 226119.43730266852 190636.6426360544 295347.51605092065 235583.1249178488 275358.52931145846 270643.9656080789 333203.0063249761 277483.18611910305 256894.408216343 1.0862845407484514 0.880203811646389 0.7420817134933907 1.149684487496491 0.9170426345732409 1.0718743596768596 1.0535222136098688 1.2970426590382225 1.080144904849082 1.0 17.97081596208173 -6.895639995737601 1.291382349889769 1.138145020305617 0.9373549616690282 0.232778706993918 0.12770649985998195 0.5612826111429284 1.9428328228574412 0.06605968954485746 0.05272019419316771 1.2716277721297788e-07 6.895639995737601 -0.20079005863658872 IHPMAYQLQLQAAS(ph)NFKSPVK ddPTM_PC-9_Lapatinib_30min_R1 4 IHPMAYQLQLQAASNFKSPVK 21 1 Q5SRQ6;P67870 Q5SRQ6 CSNK2B Casein kinase II subunit beta 1 IHPMAYQLQLQAAS(0.775)NFKS(0.225)PVK;IHPMAYQLQLQAAS(0.5)NFKS(0.5)PVK;IHPMAYQLQLQAAS(0.5)NFKS(0.5)PVK;IHPMAYQLQLQAAS(0.564)NFKS(0.436)PVK 54.292 0.0079627 56336400.0 95359.0 78090.0 85675.0 83541.0 78476.0 80304.0 64063.5 61802.0 84237.0 74675.2 True False 93999.16317330115 77909.18740283517 78631.1322150637 89684.8838246065 73860.19596975224 76869.58511776701 67380.39456488703 64673.546539293275 74749.34200506505 87582.70882155038 1.07326165675949 0.8895498717854801 0.8977928779900437 1.0240021692790902 0.8433193830558754 0.877679922807465 0.7693344436534211 0.7384282515292547 0.8534714558482851 1.0 16.418358450748805 -6.366079961239784 6.419485787158283 0.8303566062286352 0.9597587203622853 0.33386225988517026 0.08341546039126281 0.2737544782970259 14.397497360363749 0.025754208586015948 0.029223501494887564 4.3044735028003504e-07 6.366079961239784 0.1294021141336501 IHPMAYQLQLQAASNFKS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 2 IHPMAYQLQLQAASNFKSPVK 21 1 Q5SRQ6;P67870 Q5SRQ6 CSNK2B Casein kinase II subunit beta 1 IHPMAYQLQLQAAS(0.289)NFKS(0.711)PVK;IHPMAYQLQLQAAS(0.025)NFKS(0.975)PVK 121.27 8.208799999999999e-07 42233000.0 55180.7 42335.6 60892.0 74459.0 68420.0 52247.2 48028.3 63945.1 46749.2 64154.1 True False 72727.01477013847 56019.754782219636 60084.53229387396 57293.62793008243 58921.06401516768 48980.17432460703 52302.725656854396 54063.8541072164 49220.267271616605 61908.08448598832 1.1747579556689207 0.9048859328687291 0.9705441994005309 0.9254627793087301 0.9517507205137853 0.7911757362754898 0.8448448387817925 0.8732923099801722 0.7950539526506695 1.0 15.917840200721688 -1.5228787452832246 0.7427880669652209 0.8711962116117653 47.295660968168846 0.5872287372836822 0.06891517246868925 251.77328237973487 1.120165436935863 0.025474696608587886 19539.25309675166 0.029999999999800568 1.5228787452832246 46.42446475655708 IHPMAYQLQLQAASNFKS(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IHPMAYQLQLQAASNFKSPVK 21 1 Q5SRQ6;P67870 Q5SRQ6 CSNK2B Casein kinase II subunit beta 1 IHPMAYQLQLQAAS(0.263)NFKS(0.737)PVK;IHPMAYQLQLQAAS(0.008)NFKS(0.992)PVK;IHPMAYQLQLQAAS(0.034)NFKS(0.966)PVK 79.17699999999999 0.0011792999999999999 225697000.0 138318.0 103284.0 101613.0 173078.0 184488.0 155591.0 183555.0 199984.0 150927.0 111210.0 True False 161732.5054949728 113537.35293982358 104035.83928944822 163381.0007864466 148338.90075818938 147431.53405769862 166167.34157688165 194734.6319005634 153134.02184916844 131371.49266212442 1.2311080754097403 0.8642465015742142 0.7919209653575222 1.2436564240512036 1.1291559359815115 1.1222490592908094 1.2648660543444459 1.482320311312921 1.1656564049478775 1.0 17.003292722266472 -5.780915171053917 24.978893464048618 1.2175960554871552 0.9526072983036866 0.31868202821311775 0.1584744428024454 250.33765634168375 321072.4781960478 0.04566067144789585 0.06783590416609299 1.656093409760392e-06 5.780915171053917 -0.2649887571834686 IHPMAYQLQLQAASNFKS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 2 IHPMAYQLQLQAASNFKSPVK 21 1 Q5SRQ6;P67870 Q5SRQ6 CSNK2B Casein kinase II subunit beta 1 IHPMAYQLQLQAAS(0.291)NFKS(0.709)PVK;IHPMAYQLQLQAAS(0.012)NFKS(0.988)PVK 75.3 0.00069093 44719000.0 133022.0 108647.0 109128.0 100620.0 124594.0 100991.0 90263.0 84260.0 108235.0 88660.0 True False 131125.08188675295 108395.43454675158 100155.91708626198 108019.93045848035 117265.6258812287 96671.85035151937 94936.37647974907 88175.02720625291 96044.43453492195 103984.76286797569 1.261002845707654 1.0424165190853578 0.9631787804663746 1.0388053737798866 1.1277193181669805 0.9296732298582903 0.912983535869434 0.8479610355817648 0.923639501461044 1.0 16.666012616790617 -6.834127925531041 6.594453927756906 0.9110198859782844 1.0743996712896442 0.5045281068823658 0.08036018534492945 0.19115182279582402 13.787842018575592 0.029234927138399022 0.025875146951404686 1.4651162136058149e-07 6.834127925531041 0.16337978531135977 IHQDSES(ph)GDELSSSSTEQIR ddPTM_PC-9_AZD4547_30min_R2 3 IHQDSESGDELSSSSTEQIR 20 0 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 IHQDS(0.015)ES(0.985)GDELSSSSTEQIR;IHQDS(0.014)ES(0.977)GDELS(0.008)SSSTEQIR;IHQDS(0.034)ES(0.966)GDELSSSSTEQIR 174.5 1.6811e-09 37248400.0 47411.9 56017.9 136375.0 191511.0 159215.0 122782.0 94078.0 169504.0 112781.0 125013.0 True False 62487.89797121686 74124.59068526009 134566.57839415804 147361.09776545502 137110.74550094857 115104.42213025558 102450.75974676489 143311.05161442538 118742.37341302505 120636.33292099547 0.5179857216991176 0.6144466504448884 1.1154730514088609 1.221531641399955 1.1365626107910805 0.9541439079189955 0.8492529345521446 1.1879592834463855 0.984300256298318 1.0 16.880304954068635 -5.211103074380023 5.191634436487212 1.060828056233308 0.5508803943696985 0.763084237424706 0.1093758087301471 0.09913676256944066 6.142300911479595 0.030239570652464142 0.0825041530351444 6.150308854746367e-06 5.211103074380023 -0.5099476618636094 IHQDSES(ph)GDELSSSSTEQIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IHQDSESGDELSSSSTEQIR 20 0 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 IHQDSES(1)GDELSSSSTEQIR;IHQDS(0.425)ES(0.575)GDELSSSSTEQIR 110.25 4.1256999999999995e-05 17984000.0 24514.6 30940.0 60210.0 54085.0 78578.0 63814.0 48903.0 51088.0 51310.0 33563.0 True False 28664.437594579635 34011.51872466347 61645.634747696604 51054.79279593581 63181.20497689282 60467.481501873335 44270.553812940234 49746.99413221038 52060.31168101682 39647.706215438186 0.7229784603129994 0.8578432895928775 1.5548348349013132 1.2877111356332611 1.59356520232414 1.5251192886999414 1.116598109670768 1.2547256545408847 1.313072473805442 1.0 15.274949781989756 -5.14448099821792 5.3058707286067115 1.3458940450917976 0.7581679421485007 0.5906946271101192 0.18054957880194786 0.14329537235968307 5.587865567426169 0.04654644234869832 0.13084302223574848 7.169997459418756e-06 5.14448099821792 -0.5877261029432969 IHQDSES(ph)GDELSSSSTEQIR ddPTM_PC-9_Lapatinib_30min_R1 3 IHQDSESGDELSSSSTEQIR 20 0 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 IHQDS(0.025)ES(0.975)GDELSSSSTEQIR;IHQDS(0.095)ES(0.902)GDELS(0.003)SSSTEQIR;IHQDS(0.083)ES(0.917)GDELSSSSTEQIR 228.65 4.4462e-36 30003500.0 71793.0 53233.0 83202.0 61041.0 73339.0 77152.0 52761.0 52395.0 80206.0 58531.0 True False 70769.21865477641 53109.742259125735 76361.45272900785 65530.15876680676 69025.34421002163 73852.38881009613 55492.70641844432 54829.462977351446 71172.3556733769 68648.0053623449 1.0308998532620883 0.7736531014819218 1.1123622940819482 0.9545821239949914 1.0054967197617035 1.0758125952863586 0.8083658968026392 0.7987043860625663 1.0367723766729668 1.0 16.06693018155825 -7.262727632597616 24.99751341614576 0.894186035634544 0.9865688299232995 0.10744262627941648 0.1097622510156761 241.05767186876585 4677454.789839346 0.04355644915869283 0.03118772346000263 5.46100240003981e-08 7.262727632597616 0.09238279428875551 IHQETFGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IHQETFGK 8 0 Q15393;J3QL37;Q15393-2 Q15393 SF3B3 Splicing factor 3B subunit 3 0 82.279 0.014011000000000001 2504600.0 27834.0 28788.0 27807.0 31796.0 37324.0 31705.0 27579.0 29240.0 32377.0 23273.0 False True 32545.746453441203 31645.882386736022 28470.024338634743 30014.57320402283 30010.630132575836 30042.33398653736 24966.51746533095 28472.48098234091 32850.45237373382 27492.210671033376 1.1838170034006172 1.1510854025310915 1.0355669349148273 1.091748261468369 1.0916048364272117 1.0927580304842808 0.9081305888448042 1.0356562927236832 1.1949003580256297 1.0 14.746735299347037 -3.967998895000345 0.6847715028749378 1.0482650411921586 1.536415208074072 0.2685083623953587 0.07121229442689644 11.649016675690053 1.8261505435036045 0.030448683111786473 5.709020786088028 0.00010764679525437572 3.967998895000345 0.4881501668819135 IHRAS(ph)DPGLPAEEPK ddPTM_PC-9_AZD4547_30min_R2 4 IHRASDPGLPAEEPK 15 1 F8VPD4;P27708 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 IHRAS(1)DPGLPAEEPK;IHRAS(1)DPGLPAEEPK;IHRAS(1)DPGLPAEEPK;IHRAS(1)DPGLPAEEPK 85.49600000000001 0.0027239 159506400.0 216746.0 223307.0 238337.0 236342.0 222882.0 262246.0 256088.0 267416.0 243063.0 253294.0 True False 285666.71940313233 295486.62074360845 235176.49565337066 181857.00334750043 191938.68152336407 245847.71616337166 278879.33589180786 226093.00180835373 255910.81395705056 244426.25415669373 1.168723549721466 1.208898863025498 0.9621572627898092 0.7440158340393247 0.7852621322761769 1.0058155046051913 1.140954914413684 0.9249947498005384 1.046985786530912 1.0 17.899039729754648 -5.281484051262209 7.371423136971808 0.9436447778359838 1.1892072092997983 0.42207778161857357 0.11092307479472466 0.1681745120200067 47.12470910033211 0.03240710492764571 0.071329913556377 5.230171727595694e-06 5.281484051262209 0.2455624314638145 IHRAS(ph)DPGLPAEEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IHRASDPGLPAEEPK 15 1 F8VPD4;P27708 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 IHRAS(1)DPGLPAEEPK;IHRAS(1)DPGLPAEEPK;IHRAS(1)DPGLPAEEPK;IHRAS(1)DPGLPAEEPK 71.842 0.012619 104133400.0 192166.0 224364.0 183807.0 216730.0 226655.0 185011.0 249937.0 195851.0 203495.0 175906.0 True False 224695.90834849357 246637.37514998062 188189.6559719295 204587.32074814057 182243.57980653178 175308.69746674856 226261.1579728206 190710.1187712878 206470.7294002826 207796.3653288697 1.0813274235710415 1.186918619869212 0.9056445990962856 0.9845567819453901 0.8770296800817632 0.8436562265624599 1.0888600366744987 0.9177740836297098 0.9936205047355421 1.0 17.66481089399234 -5.263382317676468 24.996659516967036 0.9480465172403874 1.134123028341138 0.5153018421496061 0.07082896785742941 121.31000846011423 1560722.5479670232 0.0181939620804789 0.041163453166327316 5.452776314948642e-06 5.263382317676468 0.18607651110075074 IHRAS(ph)DPGLPAEEPK ddPTM_PC-9_Lapatinib_30min_R1 4 IHRASDPGLPAEEPK 15 1 F8VPD4;P27708 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 IHRAS(1)DPGLPAEEPK;IHRAS(1)DPGLPAEEPK;IHRAS(1)DPGLPAEEPK;IHRAS(1)DPGLPAEEPK 78.08800000000001 0.0057824 213771400.0 229328.0 266726.0 269763.0 266894.0 277720.0 284297.0 286761.0 247205.0 269977.0 262200.0 True False 226057.740666395 266108.41233459685 247584.12745529326 286522.27509228425 261385.05561852796 272138.2800386758 301608.08144765056 258691.0467662211 239569.3472761551 307520.9206404606 0.7350971120780799 0.8653343381659507 0.8050968595556375 0.9317163674443891 0.8499748734952813 0.8849423300109309 0.980772562788588 0.8412144651084432 0.779034306925247 1.0 18.23032503473447 -3.673617566829306 0.847430866893661 0.8882922263680777 3.1027945263994167e-10 0.3164609585695476 0.06669080748966205 16.698100354523387 2.2193899249045104 0.02289249343708787 21.415926712286158 0.00021202273536761887 3.673617566829306 -0.8882922260577982 IHRAS(ph)DPGLPAEEPKEK ddPTM_PC-9_AZD4547_30min_R2 3 IHRASDPGLPAEEPKEK 17 2 F8VPD4;P27708 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 IHRAS(1)DPGLPAEEPKEK;IHRAS(1)DPGLPAEEPKEK;IHRAS(1)DPGLPAEEPKEK 66.965 0.0062083 105436300.0 131176.0 97362.0 141924.0 227044.0 181041.0 139747.0 131820.0 142488.0 131340.0 172441.0 True False 172887.23936970104 128832.36248231893 140041.9950285056 174702.5135948326 155906.5821451325 131008.59799837814 143551.72463082304 120469.75364850566 138282.36426407582 166403.89307695575 1.0389615060853594 0.7742148341609931 0.8415788383252624 1.049870350773819 0.9369166746178912 0.7872928666265725 0.8626704698815886 0.723959947215855 0.8310043816109834 1.0 17.344329660662915 -6.753157380717302 24.955784121156857 0.8250883368669946 0.9216828255255415 0.14667338978690037 0.10113299325016385 326.402272795522 983532.3265855975 0.03363713774010048 0.033096516345246636 1.7653979554419237e-07 6.753157380717302 0.09659448865854692 IHRAS(ph)DPGLPAEEPKEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IHRASDPGLPAEEPKEK 17 2 F8VPD4;P27708 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 IHRAS(1)DPGLPAEEPKEK;IHRAS(1)DPGLPAEEPKEK;IHRAS(1)DPGLPAEEPKEK;IHRAS(1)DPGLPAEEPKEK 69.331 0.0051852 93511500.0 457546.0 251768.0 342964.0 648697.0 609811.0 689841.0 692987.0 949027.0 724120.0 545859.0 True False 534999.5008545739 276761.863163254 351141.5624582138 612352.6101940504 490322.91211489163 653664.5235643248 627342.254568596 924116.0468272229 734708.8850995481 644818.9156825325 0.8296895265367392 0.429208660652123 0.5445584084432992 0.9496505069890561 0.7604040455232166 1.0137179720796952 0.9728967921242856 1.4331404125281562 1.1394034313057773 1.0 19.29853454020268 -6.64902909225625 0.884748826639175 1.1967867981986002 0.6012266982706229 0.607933552495433 0.17080865781311858 0.36796564440835433 0.6313174080181446 0.10143304295014363 0.10648940955859929 2.243731617011126e-07 6.64902909225625 -0.5955600999279773 IHRAS(ph)DPGLPAEEPKEK ddPTM_PC-9_Lapatinib_30min_R1 3 IHRASDPGLPAEEPKEK 17 2 F8VPD4;P27708 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 IHRAS(1)DPGLPAEEPKEK;IHRAS(1)DPGLPAEEPKEK;IHRAS(1)DPGLPAEEPKEK 64.26 0.0073782 128819000.0 330033.0 175331.0 208507.0 200792.0 174390.0 190636.0 130574.0 151998.0 238969.0 153062.0 True False 325326.6688993602 174925.0318418043 191364.3593202953 215558.91350247638 164132.72306393148 182482.94267422095 137334.48281651136 159060.38197597986 212053.79476487052 179518.562757705 1.8122174325696414 0.9744119446739302 1.0659864717086585 1.2007611368492004 0.9142938788199877 1.0165129436810219 0.7650154987140287 0.8860386331783561 1.181236032125982 1.0 17.453773505191833 -4.760533674807464 24.97167583824808 0.9956680192901617 1.8122184026457597 0.7935933650443523 0.12417303704562008 9.99550473096452 275439.06665006763 0.032358928706607025 0.1905524482425861 1.7356666756049093e-05 4.760533674807464 0.816550383355598 IHS(ph)PIIR ddPTM_PC-9_AZD4547_30min_R2 6 IHSPIIR 7 0 O60885 O60885 BRD4 Bromodomain-containing protein 4 1 IHS(1)PIIR;IHS(1)PIIR;IHS(1)PIIR;IHS(1)PIIR;IHS(1)PIIR;IHS(1)PIIR 90.709 0.008923899999999999 164141200.0 36246.9 37793.2 44039.200000000004 63325.8 48063.50000000001 43134.6 30358.800000000003 52157.7 38906.4 43037.7 True False 47772.66021764372 50009.11281369301 43455.21143329791 48727.01518385705 41390.712661400335 40437.38664315401 33060.67438721152 44097.92592971097 40962.912875010166 41530.96322265633 1.1502902054432094 1.2041404516814 1.0463328577361732 1.1732695657122412 0.996622987998037 0.9736684031709203 0.7960488228978992 1.061808407700361 0.9863222448128466 1.0 15.341899711953491 -6.376753443139897 3.805547909811891 0.9589890996533456 1.1410385740885238 0.5748721927332392 0.07366485247925988 0.1804765078737933 4.647192141149062 0.024127928441645106 0.027627172436719395 4.1999735644289833e-07 6.376753443139897 0.18204947443517827 IHS(ph)PIIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 IHSPIIR 7 0 O60885 O60885 BRD4 Bromodomain-containing protein 4 1 IHS(1)PIIR;IHS(1)PIIR;IHS(1)PIIR;IHS(1)PIIR;IHS(1)PIIR;IHS(1)PIIR 94.309 0.0076447 159173800.0 61698.3 64455.3 55332.899999999994 68990.7 73089.7 66616.1 64615.00000000001 69410.1 63953.3 47369.4 True False 72142.60359302825 70853.99621376216 56652.24618719184 65125.3747498673 58768.29796380158 63122.63444505827 58494.19942791108 67588.15842107992 64888.49602474318 55957.09724403591 1.289248498334453 1.2662200096756093 1.012422891418479 1.1638447660329374 1.050238501606073 1.1280541263563504 1.0453401321517903 1.207856764376456 1.1596115456410527 1.0 15.772033504663757 -5.168832148705518 7.122430359610282 1.1036575703140115 1.2815363913026179 0.5456632798544572 0.06611318896239182 0.19308757859756723 12.809534405988623 0.016240426191349917 0.04375314613178343 6.7790346117488975e-06 5.168832148705518 0.1778788209886064 IHS(ph)PIIR ddPTM_PC-9_Lapatinib_30min_R1 6 IHSPIIR 7 0 O60885 O60885 BRD4 Bromodomain-containing protein 4 1 IHS(1)PIIR;IHS(1)PIIR;IHS(1)PIIR;IHS(1)PIIR;IHS(1)PIIR;IHS(1)PIIR 88.37 0.0098137 132896700.0 51919.6 46132.299999999996 47454.3 43102.8 50336.3 52678.200000000004 56075.8 47347.0 57891.50000000001 43519.7 True False 51179.21698311148 46025.48349371004 43552.7906328953 46272.72369872572 47375.61779897343 50425.2761848819 58979.130543003375 49546.91446872142 51371.149645479156 51042.02215864483 1.002687879881409 0.9017174780156089 0.8532732205931794 0.9065613340103268 0.9281689046669082 0.9879168977309322 1.1555014485846395 0.9707082982473454 1.006448167077146 1.0 15.639397865792882 -6.849629787855459 3.6320296096021507 1.03507690479619 0.9124059284616336 0.46731797527214847 0.05750295363770137 0.20345390604377517 5.225896473871138 0.02156516883574947 0.019144335166135184 1.4137421685057513e-07 6.849629787855459 -0.12267097633455648 IHS(ph)PIPDMSK ddPTM_PC-9_AZD4547_30min_R2 1 IHSPIPDMSK 10 0 Q6NZY4-2;Q6NZY4 Q6NZY4-2 ZCCHC8 Zinc finger CCHC domain-containing protein 8 1 IHS(0.997)PIPDMS(0.003)K 68.536 0.03587 6347300.0 42676.0 39605.0 49860.0 53758.0 52362.0 57306.0 41865.0 48334.0 42266.0 46602.0 True False 56246.08028405635 52406.541732012935 49198.82382205473 41364.923652820595 45092.44013391127 53722.64676089691 45590.90389674859 40865.09090482617 44500.09447225083 44970.478164544846 1.2507334273443704 1.1653543362438772 1.0940249210168183 0.9198239676587004 1.002712045198189 1.194620314338849 1.013796289421999 0.9087092815714064 0.9895401669830393 1.0 15.456690603604189 -5.262338585250016 2.16429172165686 1.0089730493940117 1.2358394899834997 0.5424112948222664 0.07499491378516156 0.2916578181776451 2.5135055409437204 0.022790230635430692 0.08467922029773785 5.465896637683818e-06 5.262338585250016 0.22686644058948802 IHS(ph)PIPDMSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IHSPIPDMSK 10 0 Q6NZY4-2;Q6NZY4 Q6NZY4-2 ZCCHC8 Zinc finger CCHC domain-containing protein 8 1 IHS(1)PIPDMSK 70.942 0.030348000000000003 4522400.0 26608.0 23359.0 21311.0 28561.0 30561.0 30689.0 38083.0 29590.0 27848.0 24932.0 True False 31112.208868044956 25677.927145747057 21819.135062417557 26960.81976601134 24572.791433974133 29079.614815103123 34475.50254295652 28813.293853196537 28255.224316760028 29451.9742383966 1.0563709113762534 0.871857585433804 0.7408377749418206 0.9154163842389371 0.8343342702622133 0.9873570640704951 1.1705667764034213 0.9783145136543202 0.9593660543110089 1.0 14.846076724249682 -6.9054199944113375 5.500387212118694 1.032276271243893 0.8777605381724687 0.3605685512869148 0.09087788116601112 0.22459758801584015 10.55681228201822 0.033385758493431734 0.02936785359113507 1.2433116572192774e-07 6.9054199944113375 -0.1545157330714244 IHSSSEIQNNIS(ph)LNGK ddPTM_PC-9_AZD4547_30min_R2 1 IHSSSEIQNNISLNGK 16 0 Q9HCD6;Q9HCD6-2;Q9HCD6-3;Q9HCD6-4;J3KRP9 Q9HCD6 TANC2 Protein TANC2 1 IHSS(0.004)S(0.004)EIQNNIS(0.991)LNGK 72.209 0.016669999999999997 15654000.0 40780.0 33680.0 51576.0 140160.0 69507.0 66248.0 49489.0 56474.0 52742.0 82936.0 True False 53747.191723306314 44566.401351702996 50892.06854084028 107848.27745041362 59857.1528281534 62105.50208731891 53893.42512710356 47747.24094341773 55529.83444507294 80032.43588375367 0.6715676104295212 0.5568542411533651 0.635893034853525 1.3475571030608413 0.7479111708544687 0.7760041463379491 0.6733947871508401 0.5965986217484387 0.6938416134894292 1.0 16.288297199608216 -11.869836360925877 2.2531850180790993 2.524604396949793 0.7480317669605021 0.11612575684846982 0.21133458359846763 11361099.767166292 1741770.9396826108 87880074.79260188 0.05693821755127757 1.349471257988443e-12 11.869836360925877 -1.776572629989291 IHT(ph)REKLCEY(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 IHTREKLCEYK 11 2 A0A0M3HEQ9;Q8N859 A0A0M3HEQ9 ZNF713 Zinc finger protein 713 2 IHT(1)REKLCEY(1)K 93.345 0.0056457 0.0 23000.0 16596.0 22698.0 17892.0 15273.0 14834.0 14555.0 9466.8 14892.0 11154.0 True False 22672.015782316557 16557.572981655205 20831.858056813762 19207.837365962325 14374.672167873303 14199.584399742938 15308.586681838047 9906.662088252519 13214.706140287872 13081.954038229227 1.733075633507228 1.2656804123657077 1.5924118060602483 1.4682697485277434 1.0988168989025937 1.085432983348487 1.170206426127317 0.7572769373216269 1.0101477272944626 1.0 13.675290430378631 -6.420597807205177 1.1635244435265402 0.9621123370431136 1.536287660799961 0.7314033278445417 0.14726795547832192 0.2489852936444109 0.7041882538341161 0.06462097071912325 0.08126097695678988 3.7966642488986196e-07 6.420597807205177 0.5741753237568473 IHTDFEK ddPTM_PC-9_AZD4547_30min_R2 2 IHTDFEK 7 0 J3KQ32;Q9NTK5;Q9NTK5-2 J3KQ32 OLA1 Obg-like ATPase 1 0 ; 130.04 0.0036912 12377000.0 88347.0 90233.0 114970.0 142878.0 134211.0 112219.0 107798.0 125937.0 95337.0 117690.0 False True 116439.50826824289 119399.05264751235 113445.42267993648 109939.68454309508 115578.11930049179 105201.92819008652 117391.81316760332 106476.33039436204 100376.31918565686 113569.7089220479 1.0252690561016122 1.0513283320067819 0.9989056391594988 0.9680370372222721 1.0176843843090453 0.9263203118913964 1.0336542576522658 0.9375416332839718 0.88383002948923 1.0 16.793218567947378 -5.599488490485042 0.5155186377877127 0.9505768219300713 1.0638243984723808 0.31439504234560955 0.042292001718063243 2.4942340243993115 0.9153685784556248 0.029926963206576403 0.15613524334292114 2.5148466596672007e-06 5.599488490485042 0.11324757654230944 IHTDFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IHTDFEK 7 0 J3KQ32;Q9NTK5;Q9NTK5-2 J3KQ32 OLA1 Obg-like ATPase 1 0 ; 126.28 0.0038263000000000004 13014300.0 89771.0 90726.0 102303.0 115888.0 123206.0 102369.0 100529.0 104400.0 99250.0 84219.0 False True 104967.4572419297 99732.67769275446 104742.29150628806 109395.1710739654 99064.66874167121 97000.58942967492 91006.16535306783 101659.61062094336 100701.34348744748 99487.2380227628 1.0550846453081049 1.0024670467777534 1.0528213828021127 1.0995899901144672 0.9957525277664768 0.9750053510127707 0.9147521547662777 1.02183569110325 1.0122036302224702 1.0 16.602223851717078 -6.457759672480802 9.0585105749088 0.9821346544026011 1.0489193774208634 0.4616814375913415 0.03488520724737601 0.42493857108190153 56.59007663130299 0.01149959100946231 0.013015326583145418 3.4853012938990483e-07 6.457759672480802 0.06678472301826233 IHTDFEK ddPTM_PC-9_Lapatinib_30min_R1 3 IHTDFEK 7 0 J3KQ32;Q9NTK5;Q9NTK5-2 J3KQ32 OLA1 Obg-like ATPase 1 0 ;; 173.59 5.9575e-05 15164100.0 208765.0 177057.0 177631.0 167481.0 179937.0 176107.0 158001.0 149959.0 180105.0 150509.0 False True 205787.9728171873 176647.0353948493 163026.86485548882 179798.1114402377 169353.45942975313 168575.3141354677 166181.51867516967 156926.64259224467 159819.67831027025 176524.2801093637 1.1657771536566732 1.0006954017057006 0.9235379107876112 1.018546068160401 0.9593777089748335 0.9549695601705821 0.9414088451300509 0.8889804988584147 0.9053693815448827 1.0 17.429507107702307 IIALDGDTK ddPTM_PC-9_Lapatinib_30min_R1 2 IIALDGDTK 9 0 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 ; 124.08 0.006774 58963000.0 563630.0 543530.0 566020.0 488080.0 507110.0 446570.0 513990.0 459020.0 450940.0 502000.0 False True 555592.5328429163 542271.4896793847 519484.0205003847 523975.031387151 477282.78681661974 427471.242105515 540601.8872276152 480347.74493489665 400150.38859128434 588770.0311270453 0.9436494785228464 0.9210242726542122 0.8823207585922287 0.8899485430400367 0.8106438194603545 0.7260411017986662 0.9181885263296693 0.815849516007799 0.6796378338505132 1.0 19.16734471335085 -5.942190445010363 1.7930880322158356 0.816289710176366 0.9238314030476632 0.1871182124763785 0.08550801382353125 0.5493159496421876 3.5798498585164746 0.02717654878455641 0.04695895408057165 1.1423772744040938e-06 5.942190445010363 0.10754169287129722 IIAPPERK ddPTM_PC-9_AZD4547_30min_R2 1 IIAPPERK 8 1 P60709;P63267-2;Q562R1;A0A2R8YFE2;P63261;P68133;P68032;P63267;P62736;A6NL76 P60709;P63261;P68133 ACTB;ACTG2;ACTBL2;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 0 84.568 0.008782 35275000.0 67312.0 60415.0 84322.0 109640.0 92881.0 73671.0 84110.0 116040.0 60089.0 79017.0 False True 88715.81582342318 79942.96727028313 83203.83518498404 84364.19192111412 79986.07639276209 69064.34072386904 91595.62705733949 98108.68433392694 63265.181865875165 76250.6388809029 1.1634763606635459 1.0484235731473324 1.0911886956769168 1.1064063614323798 1.0489889339510141 0.9057542564560245 1.2012440603993386 1.2866604893260563 0.829700351293975 1.0 16.218461805065765 -8.276514213862914 0.010132227976755377 1.4851977681104192e-05 2.1152337727409294 0.05988935201655854 0.12461198565256035 4952.416614279672 42.427909389662815 4459.6638471923025 4390.565670384297 5.290366822810093e-09 8.276514213862914 2.1152189207632484 IIAPPERK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IIAPPERK 8 1 P60709;P63267-2;Q562R1;A0A2R8YFE2;P63261;P68133;P68032;P63267;P62736;A6NL76 P60709;P63261;P68133 ACTB;ACTG2;ACTBL2;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 0 ; 96.492 0.0038621000000000003 58923000.0 96525.0 72230.0 93312.0 119242.0 123908.0 112470.0 109921.0 128043.0 99260.0 86517.0 False True 112864.77604434906 79400.51704856004 95536.91196773072 112561.25732778007 99629.1168810203 106571.87520788053 99508.4871208762 124682.00692277255 100711.48971852908 102201.84723180486 1.1043320556463085 0.7768990404691127 0.9347865479480293 1.1013622588687555 0.97482696819609 1.0427587963861746 0.973646659195701 1.2199584479131795 0.9854175090407564 1.0 16.641061746720958 -5.67757487099896 7.355794953952102 1.045868464595497 0.9206223252058022 0.17290145392384026 0.10193864872572247 0.3297355798086129 24.528288639836074 0.026517549666001415 0.04604497349042438 2.100995532819919e-06 5.67757487099896 -0.12524613938969476 IIAPPERK ddPTM_PC-9_Lapatinib_30min_R1 2 IIAPPERK 8 1 P60709;P63267-2;Q562R1;A0A2R8YFE2;P63261;P68133;P68032;P63267;P62736;A6NL76 P60709;P63261;P68133 ACTB;ACTG2;ACTBL2;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 0 ; 78.77 0.013704 88046000.0 59650.0 55733.0 61830.0 67867.0 62053.0 60489.0 52367.0 47284.0 62982.0 49785.0 False True 58799.38006152972 55603.95366272533 56746.57607070208 72858.16557767532 58403.16454089193 57902.02647674601 55078.30702630112 49480.98725872859 55888.303930137714 58390.27091565735 1.0070064608274094 0.9522811384630027 0.9718498506826673 1.2477792008007007 1.0002208180409575 0.9916382570031814 0.9432788401660228 0.8474183538247683 0.9571509611741033 1.0 15.833440384424811 -7.053958985296036 2.319643623515194 0.9237151310882743 1.0387454530309403 0.23207141866199832 0.08416980023756507 0.4453585393936262 4.752313198286633 0.038562301899986606 0.029373164360276115 8.831633022864805e-08 7.053958985296036 0.11503032194266605 IIAPSRGS(ph)PLPVLSWANR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IIAPSRGSPLPVLSWANR 18 1 I3L1Q9;I3L413;C9J2U0;P24864-2;P24864-3;P24864 I3L1Q9 CCNE1 G1/S-specific cyclin-E1 1 IIAPS(0.27)RGS(0.73)PLPVLSWANR 53.861000000000004 0.021357 3268000.0 7332.5 7608.6 7511.0 8408.3 8422.7 9735.5 7026.6 7770.0 10528.0 8310.8 True False 8573.747426523585 8363.931524514368 7690.090725626123 7937.210211076397 6772.332397857854 9224.953241631747 6360.989579821402 7566.045732995512 10681.952082980804 9817.482251743395 0.8733142782102868 0.8519426172661627 0.7833057935256783 0.8084771642614278 0.6898237474944473 0.9396455226586811 0.6479247343372394 0.7706706810345318 1.0880541272263462 1.0 13.26113736942084 -8.258540045836051 24.988145346303178 1.0440270810664787 0.7938811017391575 0.5927713006789694 0.08234051835865511 156.90094685213205 1352294.1991972192 0.05986733781448172 0.020392272678211584 5.513913568222065e-09 8.258540045836051 -0.2501459793273212 IIDVVYNASNNELVR ddPTM_PC-9_Lapatinib_30min_R1 2 IIDVVYNASNNELVR 15 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 0 ; 122.46 0.00022927 10293800.0 31069.0 30210.0 35664.0 27106.4 29919.0 33935.0 29880.0 29143.0 29519.0 31311.0 False True 30625.9503626432 30140.050601096875 32731.84358702118 29099.89508029962 28159.2232430172 32483.679156348695 31427.040196037146 30497.090171752145 26194.259371149466 36723.064630715024 0.8339704398479799 0.8207389798259881 0.8913156871892548 0.7924146683542469 0.7667993814292106 0.8845579605896909 0.8557847911677746 0.8304614682469748 0.7132917591316901 1.0 15.164398839800196 -6.79912634866156 24.99971237667824 0.8461583170894397 0.8233433608860304 0.04767016954330139 0.07213054532047365 897.5632677322081 595394.1958041411 0.025045002973913526 0.02208809356360898 1.5880846622244522e-07 6.79912634866156 -0.02281495620340923 IIEDGDGAGAET(ph)PVIENR ddPTM_PC-9_AZD4547_30min_R2 2 IIEDGDGAGAETPVIENR 18 0 A0A5H1ZRS1;Q15154-5 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 IIEDGDGAGAET(1)PVIENR;IIEDGDGAGAET(1)PVIENR 121.03 0.00017716 3489500.0 6316.2 6819.5 10755.8 13287.699999999999 12474.5 14476.599999999999 9712.0 12474.599999999999 10215.5 10564.3 True False 8324.620214878543 9023.770012409097 10613.17106428512 10224.42605791853 10742.63100054382 13571.375913495971 10576.349185362998 10546.93720779047 10755.470474643405 10194.447072522666 0.816583788768308 0.8851652226172303 1.0410737324725585 1.0029407171553881 1.0537727965157315 1.3312517900137244 1.0374617779780997 1.0345766801043952 1.0550322541408723 1.0 13.315495907982708 -5.130259426950154 1.160796574399741 1.0900263286688998 0.7611040460693326 0.5005827322152577 0.08942461746306309 0.8056249337986389 1.3668988592404006 0.030254161701438104 0.2782495562876161 7.408675499146006e-06 5.130259426950154 -0.32892228259956724 IIEDGDGAGAET(ph)PVIENR ddPTM_PC-9_Lapatinib_30min_R1 2 IIEDGDGAGAETPVIENR 18 0 A0A5H1ZRS1;Q15154-5 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 IIEDGDGAGAET(1)PVIENR;IIEDGDGAGAET(1)PVIENR 169.72 1.9620000000000002e-07 5345300.0 26430.8 24731.1 28636.0 20291.2 19679.9 25374.7 22287.7 18177.6 22325.6 17234.0 True False 26053.891945184914 24673.83665742424 26281.65861815663 21783.482537458895 18522.366974172073 24289.48323231475 23441.648051446366 19022.19765659135 19811.055829009587 20212.87393713847 1.288975136648646 1.2206990818900494 1.3002435329034323 1.0777033788072383 0.916364839150344 1.201683803493478 1.15973849757087 0.9410931723885434 0.9801206840067115 1.0 14.302986843280054 -4.757925882000453 0.3635036749907668 0.9903790080846409 1.5530630811309076 0.5171636215633568 0.09511692883775537 5.82504253846412 0.6066377810047577 0.09566351268302985 1.4558590487975138 1.746120125593854e-05 4.757925882000453 0.5626840730462668 IIEDQQESLNK ddPTM_PC-9_Lapatinib_30min_R1 2 IIEDQQESLNK 11 0 P05455 P05455 SSB Lupus La protein 0 ; 166.86 0.00057385 10029600.0 33357.0 37916.0 41737.0 29874.0 38355.0 36256.0 34093.0 28774.0 34061.0 30131.0 False True 32881.32306307539 37828.20783155209 38305.544969479066 32071.033616742592 36099.03430883132 34705.41539686394 35858.16872166983 30110.945084651383 30224.69150176908 35339.1032029662 0.930451541857901 1.0704348555278835 1.0839421914437228 0.9075225659391011 1.021503972568306 0.9820683676531702 1.0146881350022503 0.8520574195590794 0.8552761321694252 1.0 15.108977808769778 -7.752930425078332 24.994934101360247 0.8902500784009708 1.0037425836380334 0.3285476475301522 0.06414176494524022 180.28805666107021 529597.6842524791 0.030246331270237587 0.017100240655279347 1.7663207664542085e-08 7.752930425078332 0.11349250523706256 IIEQLS(ph)PQAATSR ddPTM_PC-9_AZD4547_30min_R2 2 IIEQLSPQAATSR 13 0 P0DP91;D6R9X7;Q03468 P0DP91;Q03468 ERCC6 DNA excision repair protein ERCC-6 1 IIEQLS(0.939)PQAAT(0.001)S(0.06)R;IIEQLS(1)PQAATSR 173.19 0.00019655 49964000.0 82352.0 72422.0 123814.0 137289.0 114195.0 107258.0 82394.0 108295.0 82498.0 108364.0 True False 108538.22297198899 95830.99521060081 122172.14546136947 105639.14214390588 98340.99539918241 100551.14030433582 89726.90638167206 91560.49612153228 86858.67585699496 104570.20934343475 1.0379459279413155 0.9164273057527105 1.1683264882843023 1.0102221541601824 0.9404303196544818 0.9615658315658592 0.8580541910075596 0.8755887235610736 0.8306254372287745 1.0 16.674112379999123 -6.636953705785017 1.529152318935795 0.8848461841033944 1.0333832096987512 0.4100606604424918 0.0729217157471884 0.37061321750166254 1.793250522018247 0.030584842314690615 0.030738434620952902 2.3069930927013085e-07 6.636953705785017 0.14853702559535675 IIEQLS(ph)PQAATSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IIEQLSPQAATSR 13 0 P0DP91;D6R9X7;Q03468 P0DP91;Q03468 ERCC6 DNA excision repair protein ERCC-6 1 IIEQLS(0.994)PQAAT(0.004)S(0.002)R;IIEQLS(1)PQAATSR;IIEQLS(0.988)PQAAT(0.005)S(0.007)R;IIEQLS(1)PQAATSR 163.9 5.5877e-05 38019600.0 125824.0 124619.0 133692.0 137052.0 139740.0 121095.0 138316.0 128696.0 122385.0 88350.0 True False 147123.51806272168 136990.35074172073 136879.72430973314 129373.42076857902 112358.95013198351 114744.56502443597 125213.70715887874 125317.86636468355 124174.64909532748 104367.15562178506 1.4096725850791691 1.3125810502890247 1.311521076666782 1.239598990676855 1.0765738460781649 1.0994317545670929 1.199742451664001 1.2007404591806787 1.1897866561135628 1.0 16.671308241165143 -5.876009566373068 2.30735188735989 1.1402401781788287 1.3507102276004235 0.6936218069374962 0.06453556067640148 0.18273509142624303 1.9789862653509291 0.020141458755248406 0.03423645930623902 1.3304251118651518e-06 5.876009566373068 0.21047004942159475 IIEQLS(ph)PQAATSR ddPTM_PC-9_Lapatinib_30min_R1 2 IIEQLSPQAATSR 13 0 P0DP91;D6R9X7;Q03468 P0DP91;Q03468 ERCC6 DNA excision repair protein ERCC-6 1 IIEQLS(0.955)PQAAT(0.004)S(0.041)R;IIEQLS(0.998)PQAAT(0.001)S(0.002)R 133.9 4.4211e-05 44590000.0 127775.0 127129.0 131758.0 81223.0 108978.0 116759.0 105861.0 93071.0 109762.0 83555.0 True False 125952.90506893504 126834.64061128246 120925.3658405883 87196.4103719853 102568.1282989915 111765.48974852262 111341.964598149 97395.41843238982 97399.44771489914 97997.37041996101 1.2852682120874521 1.2942657549660905 1.2339654148103254 0.8897831645717744 1.0466416380301107 1.140494783375914 1.1361729822035087 0.9938574679607058 0.9938985841916012 1.0 16.580455417216278 -5.606562863698127 7.197245607598936 1.0387342705618816 1.283497913367061 0.7226082961761848 0.06917373057822843 0.12289288957813539 8.837582318214261 0.02031666417253236 0.03538959503424489 2.4742132954769223e-06 5.606562863698127 0.24476364280517937 IIFEDDR ddPTM_PC-9_AZD4547_30min_R2 3 IIFEDDR 7 0 D6RC06;D6REP8;D6RE99;D6RD60;P49773 D6RC06 HINT1 Histidine triad nucleotide-binding protein 1 0 ;; 143.02 0.0093071 53306000.0 160435.0 145243.0 194736.0 252109.0 230286.0 207910.0 162850.0 223436.0 173006.0 177352.0 False True 211449.99274469475 192189.95936833107 192153.6734017578 193989.16509522233 198314.76392570767 194909.35483296786 177343.33451774737 188909.10024849436 182150.74396125088 171142.96046174766 1.2355167409410108 1.1229790512551503 1.1227670298756243 1.1334919331290934 1.1587667023560295 1.1388686645778354 1.0362292088396212 1.1038087674702672 1.064319230366262 1.0 17.38484242634756 -1.5228787452929249 0.06560656701972127 0.8446798162824952 1.7092392483431225 0.7005543240991714 0.0343870099486116 171.09897973942407 0.8365353986917644 2.057491913433891 13.844617446892965 0.0299999999991305 1.5228787452929249 0.8645594320606272 IIFEDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IIFEDDR 7 0 D6RC06;D6REP8;D6RE99;D6RD60;P49773 D6RC06 HINT1 Histidine triad nucleotide-binding protein 1 0 ; 110.63 0.043476999999999995 25869000.0 95017.0 101265.0 112040.0 125275.0 127234.0 122536.0 124220.0 99233.0 104125.0 96779.0 False True 111101.50142870651 111317.91996292968 114711.4585140662 118256.24789702987 102303.41105691106 116109.99644770047 112452.98232508077 96628.23889605473 105647.6311398533 114324.26659785751 0.9718103140736755 0.9737033376693083 1.003386786792787 1.03439323440406 0.8948529835469619 1.0156198670936973 0.9836317841481625 0.8452119726772477 0.9241050415960699 1.0 16.802772138571605 -7.686839603512053 24.99967166145862 0.9134927468001496 0.9828523816614103 0.22632860145896794 0.049356217183945277 45.80362301324028 15348.128303492736 0.022361133215950697 0.012910200036741589 2.0566500312212133e-08 7.686839603512053 0.06935963486126073 IIFEDDR ddPTM_PC-9_Lapatinib_30min_R1 4 IIFEDDR 7 0 D6RC06;D6REP8;D6RE99;D6RD60;P49773 D6RC06 HINT1 Histidine triad nucleotide-binding protein 1 0 ;;; 138.24 0.014481 86608000.0 251717.0 226649.0 258399.0 216032.0 246168.0 249349.0 223298.0 226261.0 242514.0 196099.0 False True 248127.46942075575 226124.20816577342 237154.43166898494 231919.71394162552 231688.88222490886 238684.92453090905 234859.27783449457 236773.91206639045 215199.51953436577 229994.45086450753 1.0788411132881228 0.9831724518387875 1.0311311024138379 1.0083709109932055 1.0073672706190617 1.0377855797552316 1.021151931934449 1.0294766294421458 0.9356726596031761 1.0 17.811239527750665 -8.24400641766302 24.94834815595558 0.9678363275922461 1.0226956761429868 0.40418118360851607 0.02751505901143697 646.4306667833132 925112.4571649765 0.01715690637161502 0.006451319788187237 5.701558469028484e-09 8.24400641766302 0.054859348550740705 IIGEDS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 2 IIGEDSPSR 9 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 IIGEDS(0.893)PS(0.107)R;IIGEDS(0.533)PS(0.467)R 101.35 0.0035269 16991700.0 27206.0 38063.0 55154.0 45789.0 55268.0 48082.0 49199.0 56511.0 48372.0 41233.0 True False 35856.94208004588 50366.12038746648 54422.62192301662 35233.053482997944 47594.99219512256 45075.4249390543 53577.61568890799 47778.52344359316 50928.84516660477 39789.44522034845 0.9011671784181733 1.265816100439347 1.3677652860358234 0.8854874273285833 1.1961712944613345 1.1328487916690677 1.3465283416796228 1.200783855592917 1.2799586645294465 1.0 15.280098163390553 -7.110650822052718 19.057999698545657 1.225867264137647 1.134621585663163 0.0512090850957877 0.16157396258703008 13.056187927263899 2221.420852546697 0.06068132418977962 0.04700360944867521 7.750847247188747e-08 7.110650822052718 -0.09124567847448395 IIGEDS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IIGEDSPSR 9 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 IIGEDS(0.61)PS(0.39)R 110.84 0.0022751 4804200.0 14445.0 21429.0 25656.0 23582.0 25400.0 18456.0 24651.0 14195.0 17281.0 12494.0 True False 16890.25319824525 23556.329500672713 26267.73634092184 22260.776993875552 20423.05233542564 17488.13487006887 22315.87882221519 13822.39629084573 17533.701932559965 14759.063297550425 1.1443987235320374 1.5960585726725882 1.779769881824514 1.5082784418690172 1.3837634491895752 1.1849081826874062 1.5120118650022305 0.936536148140231 1.1879955779761477 1.0 13.849313541404312 -7.402024052820282 0.7854781206337923 1.0187184367783213 1.5221295545346276 0.4345823023047203 0.19605688902247084 0.6100878421064609 0.7179145022110899 0.16956086751831842 0.09405600260765837 3.96256087533125e-08 7.402024052820282 0.5034111177563063 IIGEDS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 1 IIGEDSPSR 9 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 IIGEDS(0.994)PS(0.006)R 129.0 0.001312 10879000.0 23068.0 31048.0 25332.0 26108.0 32448.0 27124.0 32803.0 25076.0 29969.0 26836.0 True False 22739.046089846892 30976.11026358345 23249.30074434781 28028.069413734866 30539.472435222517 25963.96974913223 34501.3788336883 26241.122504438674 26593.575632439366 31474.56684327772 0.7224577927655724 0.984163194932078 0.7386694425411402 0.8904989718618177 0.9702904757129353 0.8249190490345879 1.096166914877084 0.8337246588682825 0.8449226883679631 1.0 14.941898903090081 -5.989363633787027 24.863669196810992 0.9238941627489257 0.8291002223441606 0.1913747683726864 0.10265504515981123 382.84670095771463 894936.613314711 0.027708290807467045 0.041052735685386005 1.0247935096395755e-06 5.989363633787027 -0.09479394040476508 IIGS(ph)PETK ddPTM_PC-9_AZD4547_30min_R2 1 IIGSPETK 8 0 E9PMS6;H0YDG6 E9PMS6 LMO7 1 IIGS(0.932)PET(0.068)K 68.893 0.042352999999999995 6614600.0 65075.0 50473.0 55217.0 60975.0 67208.0 60982.0 48023.0 67892.0 60844.0 70500.0 True False 85767.49635591354 66787.41019668958 54484.78650185313 46918.15580435909 57877.32929452475 57168.785899783856 52296.95396712188 57400.85140295556 64060.089624512104 68031.81645852992 1.260696844809292 0.9817084663232696 0.8008721409792925 0.689650199667371 0.8507391439387035 0.8403242611437866 0.7687131799428063 0.8437353931001582 0.9416195680084647 1.0 16.053921989322646 -4.8463151348292834 2.5344562618088537 0.8294392862110254 1.3198695991701985 0.7055478396095253 0.0821021664428541 0.2238619183018439 2.0740057106398795 0.021346201152927714 0.22615271506730322 1.4245735126566957e-05 4.8463151348292834 0.49043031295917316 IIGS(ph)PETK ddPTM_PC-9_Lapatinib_30min_R1 1 IIGSPETK 8 0 E9PMS6;H0YDG6 E9PMS6 LMO7 1 IIGS(0.999)PET(0.001)K 82.029 0.017048 6663100.0 74010.0 59741.0 63766.0 63515.0 51436.0 54921.0 54602.0 48701.0 55595.0 47999.0 True False 72954.60382822836 59602.673384976086 58523.405623878156 68186.10497982887 48410.63560706683 52572.156857104084 57429.02439036214 50963.826251741455 49333.30565869623 56295.563195352755 1.2959210226757412 1.0587454854683171 1.03957403216297 1.2112163216702252 0.8599369623335285 0.9338596840158082 1.0201341123647014 0.9052902814896887 0.8763267095757331 1.0 15.780733603661462 -1.522878745280341 0.38441975140092094 0.9254339370445155 5.8655808772175355 0.5665195068617341 0.08877830207084227 52.52891334409458 0.7129267565632226 0.06818150266997838 194.04003724925963 0.029999999999999766 1.522878745280341 4.94014694017302 IIIAEVVNK ddPTM_PC-9_Lapatinib_30min_R1 1 IIIAEVVNK 9 0 E9PDF6;O43795-2;O43795;H7C2Y7 E9PDF6 MYO1B Unconventional myosin-Ib 0 109.11 0.011015 1802000.0 10155.0 8675.3 9687.1 9509.0 9338.7 9119.3 9341.2 8369.6 9574.1 12973.0 False True 10010.187837801082 8655.212875858844 8890.664031287371 10208.323581094104 8789.416026590621 8729.28879712659 9824.84162915737 8758.48217072699 8495.764038257466 15215.365764564076 0.6578999146451263 0.5688468492828781 0.5843214135537471 0.670921996819087 0.5776670875083916 0.573715343567798 0.6457183994905333 0.5756340206506972 0.5583673879233144 1.0 13.893241394991186 -10.891414940058139 3.7976890748388015 1.0015875181249505 0.6010618338682773 0.9039603434996013 0.03897152772530099 8387192.548235609 4811827.91990116 105829.18458829365 0.009247318866346934 1.2840592388043552e-11 10.891414940058139 -0.40052568425667323 IIIDKEY(ph)Y(ph)YT(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 IIIDKEYYYTK 11 1 E7EM64;Q7L5N1 E7EM64 COPS6 COP9 signalosome complex subunit 6 3 IIIDKEY(0.993)Y(0.902)Y(0.11)T(0.995)K 56.551 0.036749000000000004 0.0 14626.0 9969.0 16329.0 23529.0 20955.0 18108.0 14308.0 13917.0 15583.0 15845.0 True False 19276.763760301063 13191.284295579786 16112.466790820936 18104.752569426244 18045.759959629315 16975.703897433435 15581.38428173124 11766.44743084507 16406.685566674987 15290.271372842652 1.260720839431202 0.8627240141080218 1.0537724542573261 1.1840700618029871 1.180211882418303 1.1102290785750417 1.019039093668778 0.7695381686778748 1.0730146749269094 1.0 13.900326391531362 -7.524526250778837 24.97633822045453 0.9316235710436487 1.098551326812088 0.25763470093201923 0.12205545783980225 73.23008158653406 1110107.5367160148 0.056678186840460616 0.03303296682625005 2.9886409941347527e-08 7.524526250778837 0.1669277557684392 IIIEELSLVAAS(ph)PTLSPR ddPTM_PC-9_AZD4547_30min_R2 1 IIIEELSLVAASPTLSPR 18 0 Q16513-3;Q16513-2;Q16513;Q16513-4;B1AL79;H0Y5V5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 IIIEELS(0.001)LVAAS(0.495)PT(0.495)LS(0.008)PR 279.12 9.121899999999996e-197 0.0 780.27 2504.5 3691.6 4448.1 3629.2 3389.9 3537.4 3508.9 3151.1 2829.5 True False 1028.3796293757769 3314.0306468331373 3642.6469719514107 3422.6592674599374 3125.348224551977 3177.929017114515 3852.2217471481763 2966.680131500487 3317.6607129018516 2730.440066232771 0.3766351227019048 1.213734990127637 1.3340878699371068 1.2535192805686561 1.1446316889365262 1.1638889483112336 1.4108428142365872 1.0865208755867912 1.2150644703508462 1.0 11.414917774344532 -4.761443230617474 13.05645366060969 1.2144266108132709 0.37599197114355565 0.8314271698714154 0.11144093634333384 0.020037862803405422 301.3652571334392 0.026587195514336175 0.14845140418444874 1.7320354212738493e-05 4.761443230617474 -0.8384346396697152 IIIEELSLVAAS(ph)PTLSPR ddPTM_PC-9_Lapatinib_30min_R1 2 IIIEELSLVAASPTLSPR 18 0 Q16513-3;Q16513-2;Q16513;Q16513-4;B1AL79;H0Y5V5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 IIIEELS(0.018)LVAAS(0.923)PT(0.058)LS(0.001)PR;IIIEELSLVAAS(0.999)PT(0.001)LSPR 284.46 1.1391999999999999e-105 14188800.0 75073.0 71284.0 69413.0 68608.0 61218.0 60564.0 49380.0 55659.0 66459.0 43282.0 True False 74002.44525329799 71118.94627767587 63706.131081928565 73653.6611895789 57617.27759921875 57973.818901579536 51936.65478180435 58245.120333169245 58973.687575704564 50763.2360303602 1.4577960555753184 1.4009931564477378 1.2549659175358234 1.4509252551497802 1.1350197919762113 1.1420434045399876 1.0231155230281685 1.1473878516793987 1.1617401132668905 1.0 15.631496419889691 -6.329924007641075 5.6700138294624365 1.1046202480085074 1.3818289486460589 0.7955848950367673 0.07190260967268655 0.10192331105137784 6.24735820668453 0.022429771980379903 0.02562478162412873 4.678169922158916e-07 6.329924007641075 0.27720870063755143 IILDLIS(ph)ESPIKGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IILDLISESPIKGR 14 1 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 IILDLIS(0.893)ES(0.107)PIKGR 95.195 0.015724000000000002 5256400.0 24460.0 17926.0 22102.0 26649.0 34923.0 32371.0 35079.0 32852.0 27438.0 21912.0 True False 28600.59489297879 19705.5748111932 22628.995502301783 25155.942927223692 28080.088846853123 30673.407774111354 31756.063170033136 31989.66980957126 27839.228842403823 25884.472144703435 1.104932514485567 0.7612894209714615 0.8742305184280994 0.9718545847330011 1.0848237000884318 1.1850119099449299 1.2268383528358395 1.2358633249593654 1.0755185072646103 1.0 14.659799277544176 -6.279696623985538 2.214497244525801 1.163245753671752 0.90071781908651 0.49195503372654537 0.1037177666644321 0.23001791958260806 2.2156288378149576 0.03421656497828259 0.04338583453003899 5.251741920979394e-07 6.279696623985538 -0.26252793458524193 IILDLISES(ph)PIK ddPTM_PC-9_Lapatinib_30min_R1 1 IILDLISESPIK 12 0 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 IILDLISES(1)PIK 156.6 0.00037887 804180.0 3038.1 7382.8 5161.0 4556.2 6026.1 4493.4 6916.3 7136.9 5133.2 5765.6 True False 2994.776136880696 7365.705580197879 4736.68250203612 4891.278147037644 5671.656645768441 4301.227756627001 7274.392172284192 7468.506428534392 4555.044961007637 6762.176277820915 0.442871645730855 1.0892507496967305 0.7004671732045556 0.723328991449161 0.8387324454067782 0.6360715219351033 1.075747196378669 1.104453081625534 0.6736063618967771 1.0 12.723271909858662 -7.264165670159647 24.99386088537628 0.972156082575459 0.756543043052775 0.2526234234601701 0.1878140537166093 360.24925924649983 3302635.3686266956 0.0728379762133076 0.05162070814169775 5.4429498122421265e-08 7.264165670159647 -0.21561303952268407 IILDLISES(ph)PIKGR ddPTM_PC-9_AZD4547_30min_R2 2 IILDLISESPIKGR 14 1 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 IILDLIS(0.013)ES(0.987)PIKGR;IILDLIS(0.069)ES(0.931)PIKGR 88.95100000000001 0.0026021 28007800.0 18729.7 15633.4 26586.3 32754.2 30209.0 28788.2 19824.7 24779.0 21913.0 21329.4 True False 24685.354998038478 20686.590822200527 26233.74829082018 25203.22523734544 26015.001795296677 26988.069303075612 21589.059894467246 20949.974914774015 23071.276443723862 20582.664198164086 1.1993274903761166 1.0050492308981902 1.2745555210078272 1.22448799604832 1.2639278154096854 1.3112038870790532 1.0488953075565857 1.0178456351944318 1.120908169204925 1.0 14.329142114779929 -7.289379079786763 23.404436458898996 1.0483993210049085 1.2092580087514815 0.49244563579896694 0.08259001978671708 322.42090759922104 270082.34878885775 0.03666446505015871 0.024727587548791338 5.135951574245594e-08 7.289379079786763 0.16085868774657297 IILDLISES(ph)PIKGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IILDLISESPIKGR 14 1 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 IILDLIS(0.01)ES(0.99)PIKGR;IILDLIS(0.272)ES(0.728)PIKGR 80.508 0.0054326999999999995 49618300.0 6179.4 6517.700000000001 6769.700000000001 10133.8 8791.7 6952.5 9112.0 7311.4 8830.7 5829.299999999999 True False 7225.450371286717 7164.734182021309 6931.115322230219 9566.036040222878 7069.029496746523 6587.898660823241 8248.845394832859 7119.483497068644 8959.832281456938 6886.105945286588 1.0492795824950099 1.0404623801824362 1.0065362597237468 1.3891793295411976 1.0265641500309972 0.9566943513746743 1.1978969624304199 1.0338910777203185 1.301146446576207 1.0 12.749472662137409 IILDLISESPIK ddPTM_PC-9_Lapatinib_30min_R1 2 IILDLISESPIK 12 0 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 ; 213.8 3.9950999999999993e-60 0.0 16524.7 14415.1 18147.9 13831.599999999999 14645.8 14617.4 14556.5 13148.1 12023.900000000001 13707.0 False True 16289.054747741153 14381.722721611097 16655.849714919852 14848.822004864991 13784.36283875066 13992.247876823667 15310.164344498493 13759.008725498883 10669.641764719809 16076.236686570557 1.0132380522456712 0.8945951096642544 1.0360540243123866 0.9236503725569741 0.857437166887793 0.8703683672754227 0.9523475327585833 0.8558600494475556 0.6636902636319605 1.0 13.972642102667598 -6.053093501698653 4.232231679293565 0.8646780639904064 0.9740240508504299 0.2507830222267896 0.08856404120127961 0.32339798097609046 12.016079299364508 0.02628999796743937 0.03590675074387206 8.84925068831126e-07 6.053093501698653 0.1093459868600235 IILDLISESPIKGR ddPTM_PC-9_AZD4547_30min_R2 1 IILDLISESPIKGR 14 1 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 141.34 0.00017203 1104600.0 2592.4 2346.2 2467.8 4107.2 4245.4 2891.0 2072.1 3632.2 2178.4 3552.2 False True 3416.7292747302386 3104.563267558359 2435.075359568126 3160.348495607441 3655.999490938216 2710.225312982113 2256.5128858104063 3070.926949652616 2293.5457767082567 3427.838559205531 0.9967590992739556 0.9056912144304434 0.7103821599266047 0.9219653846066524 1.066561166108583 0.7906513875059101 0.6582903035939351 0.8958785242104177 0.6690938727405619 1.0 11.743083449153875 -6.9406501340564315 24.99954618631008 0.7867550338869028 0.9099667006034646 0.1699265003527588 0.1264039841398867 130.87251016018942 55125.682886944676 0.04427573445784798 0.03904752211301408 1.1464361340210179e-07 6.9406501340564315 0.12321166671656181 IILDLISESPIKGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IILDLISESPIKGR 14 1 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 ; 218.02 1.9809000000000003e-15 5312700.0 25339.5 20194.4 27995.7 26952.6 30510.8 26621.1 28321.0 25124.0 26271.1 19239.4 False True 29628.976872061972 22199.166571859863 28663.223662283486 25442.533203508177 24532.42776361042 25225.0426522318 25638.229853716137 24464.521621078406 26655.26513746171 22727.35092099339 1.3036704970614728 0.9767599685960038 1.261177502029376 1.119467609399508 1.0794231078180638 1.1098980580676157 1.1280782323836056 1.0764352478264583 1.1728276309070442 1.0 14.472141914304832 -14.522878745280336 0.09470710610057353 0.6253739784122693 1.2195341439290583 0.199245128883073 0.0872234266855964 351.41965123457584 2.2818139648523967 26.96889036213191 1.6432691166988156 3.0000000000000132e-15 14.522878745280336 0.5941601655167891 IILLAEGR ddPTM_PC-9_Lapatinib_30min_R1 1 IILLAEGR 8 0 P23526;P23526-2 P23526 AHCY Adenosylhomocysteinase 0 99.375 0.024045 3018900.0 22445.0 21922.0 29136.0 22053.0 24039.0 26008.0 21366.0 26596.0 24272.0 21434.0 False True 22124.930184091114 21871.240955883655 26740.550548212428 23674.851186651416 22625.073282492416 24895.698467609145 22472.226935359107 27831.747253471473 21538.23176450894 25138.83834099025 0.8801094897060222 0.870017964204074 1.0637146468542462 0.9417639298013337 0.9000047247847964 0.9903281181857695 0.8939246368722183 1.107121453901483 0.8567711631046083 1.0 14.617630364295385 -5.1790241967424295 24.999878523621298 0.9676452753101483 0.875062808005811 0.21000428256863868 0.07298500412456746 140.76412436383305 42697.14285083872 0.017368788991722527 0.045953495507342415 6.621796092983698e-06 5.1790241967424295 -0.09258246730433728 IILNSHS(ph)PAGSAAISQQDFHPK ddPTM_PC-9_AZD4547_30min_R2 2 IILNSHSPAGSAAISQQDFHPK 22 0 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 IILNS(0.365)HS(0.63)PAGS(0.005)AAISQQDFHPK;IILNS(0.1)HS(0.894)PAGS(0.005)AAISQQDFHPK 93.5 0.00016233 18825900.0 91009.0 89758.0 146948.0 216494.0 164289.0 149382.0 127410.0 144005.0 123849.0 145663.0 True False 119947.96889520303 118770.51818664353 144999.37350588234 166584.65309895732 141480.30818456438 140041.11992524858 138749.2431741251 121752.33615569747 130395.40529725532 140563.38270636636 0.8533372389434561 0.8449605857505036 1.0315586514361472 1.1851212591187334 1.0065232172173422 0.9962845033246761 0.987093797137545 0.8661739196333604 0.9276626870146423 1.0 17.100861290268085 -10.510348491538464 17.850574736690312 0.999999999075224 0.9709959856563383 0.008712753141166707 0.09709389531191115 0.0 0.0 0.10469135952638862 0.025391384318636124 3.0878166770054785e-11 10.510348491538464 -0.0290040134188857 IILNSHS(ph)PAGSAAISQQDFHPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IILNSHSPAGSAAISQQDFHPK 22 0 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 IILNS(0.355)HS(0.644)PAGS(0.001)AAISQQDFHPK 57.537 0.0092527 6613100.0 18071.0 25052.0 29100.0 25951.0 31640.0 28098.0 25284.0 25738.0 29088.0 21596.0 True False 21130.06338148078 27538.99699709987 29793.854362364553 24497.04960427717 25440.36912964043 26624.491416297944 22888.91647969205 25062.40477166519 29513.356970910503 25511.18384615805 0.8282666735069193 1.0794872226694885 1.1678742367281976 0.960247464484734 0.9972241697231826 1.0436399806788095 0.897211067025378 0.9824085359111846 1.1568791612685265 1.0 14.638842228288054 -8.225510967592779 24.924536386538477 1.0784397407297122 1.000492066889795 0.10796052452444416 0.09524189364555118 1217.4371426486032 844572.4790814627 0.06480186425503334 0.024490245130753662 5.949617315153786e-09 8.225510967592779 -0.07794767383991719 IILNSHS(ph)PAGSAAISQQDFHPK ddPTM_PC-9_Lapatinib_30min_R1 2 IILNSHSPAGSAAISQQDFHPK 22 0 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 IILNS(0.093)HS(0.899)PAGS(0.008)AAISQQDFHPK;IILNS(0.116)HS(0.881)PAGS(0.003)AAISQQDFHPK 97.08 0.00012178 12642000.0 171838.0 131299.0 193085.0 142765.0 172656.0 164458.0 149778.0 152907.0 197006.0 115437.0 True False 169387.55860877014 130994.9852324865 177210.29662965424 153264.4143500786 162500.71353475653 157424.51471032263 157532.77197061738 160011.61743444778 174817.1097148504 135390.13163986616 1.251107126916282 0.9675371731001 1.3088863603517908 1.1320205726496928 1.2002404574581826 1.162747334710238 1.163546929621503 1.1818558376180184 1.2912101317683837 1.0 17.046763061554515 -10.665877031841879 3.8187565723004484 0.9999117717479737 1.1792438361831092 0.26889588969924894 0.09084267950627324 60753444.245673336 86879293.36285709 67407.30353127558 0.021219469063910153 2.1583554494357563e-11 10.665877031841879 0.1793320644351355 IILS(ph)PFATTTK ddPTM_PC-9_AZD4547_30min_R2 2 IILSPFATTTK 11 0 Q9P0V3 Q9P0V3 SH3BP4 SH3 domain-binding protein 4 1 IILS(0.876)PFAT(0.095)T(0.024)T(0.006)K;IILS(0.998)PFAT(0.001)TTK 89.663 0.009159700000000002 18669900.0 151914.0 176595.0 150302.0 128433.0 135517.0 161648.0 172359.0 213315.0 180873.0 161273.0 True False 200219.49199250486 233675.88024655532 148308.89727441783 98824.75612006978 116702.80374369283 151540.12500620252 187698.61709637355 180352.06824105125 190433.57752045212 155626.88135768077 1.2865353995775053 1.5015136087543435 0.9529773775621458 0.6350108365465386 0.7498884686603219 0.9737400356813322 1.206080951175662 1.1588747822205858 1.2236547816104746 1.0 17.24773175231787 -5.268351989603855 24.87751436772412 0.9794384438333746 1.3940245115868628 0.43782993769687384 0.18406322141236028 468.4745146609081 1685979.4454520624 0.05559139561826212 0.1199469166852658 5.3907353385183435e-06 5.268351989603855 0.41458606775348816 IILS(ph)PFATTTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IILSPFATTTK 11 0 Q9P0V3 Q9P0V3 SH3BP4 SH3 domain-binding protein 4 1 IILS(1)PFATTTK 90.697 0.0085961 5802700.0 54475.0 66260.0 56936.0 55165.0 60218.0 43082.0 59131.0 39673.0 45195.0 42251.0 True False 63696.541569706416 72837.85490291528 58293.5701709824 52074.283897343055 48418.71517852998 40822.70407847352 53529.6836086328 38631.62578701813 45855.891374460254 49910.771841268026 1.2762083057397204 1.4593614207081909 1.1679556941410225 1.0433475976479722 0.9701055181538114 0.8179137002389499 1.072507629793305 0.7740137922506762 0.9187574081261742 1.0 15.60706359400716 -5.701560663739352 1.6160552805430808 0.915631897275812 1.3753558070930714 0.7740729002875407 0.09378969301909462 0.16348812790672487 0.8582800403886808 0.028393029639121582 0.06697624894871372 1.9881050856789335e-06 5.701560663739352 0.4597239098172594 IINEPT(ph)AAAIAYGLDR ddPTM_PC-9_AZD4547_30min_R2 2 IINEPTAAAIAYGLDR 16 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;P17066 A0A0G2JIW1;P17066 HSPA1B;HSPA1A;HSPA6 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 6 1 IINEPT(1)AAAIAYGLDR;IINEPT(1)AAAIAYGLDR 114.56 0.001492 1147800.0 8306.1 9028.599999999999 11214.8 14623.9 11778.2 12388.8 9472.2 12881.1 8968.1 9209.9 True False 10947.267022387306 11946.918386104086 11066.084424379858 11252.585792002734 10143.00023653095 11614.12637754161 10315.207449917161 10890.621973231191 9442.135457260983 8887.464204275384 1.2317649636350758 1.3442437698209717 1.2451340641188104 1.2661188313523208 1.1412704460347172 1.3067986672682792 1.160646863135038 1.2253913740650761 1.06241051893281 1.0 13.117556128714153 -8.367466875655666 0.536933257925021 0.9886204743655351 1.2717034326042476 0.6806591768152299 0.05767842606480933 0.5044238758831454 0.3607947599290015 0.05983232708543697 0.029514435097017983 4.290749142303201e-09 8.367466875655666 0.28308295823871243 IINEPTAAAIAYGLDK ddPTM_PC-9_Lapatinib_30min_R1 2 IINEPTAAAIAYGLDK 16 0 P11142;E9PKE3;P11142-2;E9PN89;E9PLF4;E9PI65;P54652;P11021 P11142;P11021 HSPA8;HSPA2;HSPA5 Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2;78 kDa glucose-regulated protein 0 ; 140.27 9.2175e-05 16752500.0 37178.0 32820.0 36524.0 34336.0 32967.0 30777.0 39561.0 28888.0 34769.0 37856.0 False True 36647.83490238979 32744.00730645479 33521.13770671718 36861.18398153824 31027.945875615755 29460.739454691135 41609.275006540345 30230.241940828866 30852.949086198576 44399.35916005073 0.8254136004594512 0.7374882864506952 0.7549914760228913 0.8302188292551952 0.6988376963677848 0.6635397449880102 0.9371593598129944 0.6808711322128534 0.6948962703488563 1.0 15.438251233077782 -10.664751300158494 5.0772436960606235 1.0000106370593695 0.7580398739076425 0.4488286361767364 0.080400107517992 9.504989345366423e-06 1.606573307841879e-06 0.07643378246668542 0.01853710047123805 2.163957364678408e-11 10.664751300158494 -0.24197076315172705 IINEPTAAAIAYGLDKK ddPTM_PC-9_AZD4547_30min_R2 2 IINEPTAAAIAYGLDKK 17 1 P11142;E9PKE3;P11142-2;E9PN89;E9PI65;P54652 P11142 HSPA8;HSPA2 Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2 0 ; 188.16 1.3031999999999999e-08 13155200.0 63555.0 59518.0 78019.0 102155.0 96815.0 93858.0 66508.0 85410.0 61090.0 85810.0 False True 83764.1679738777 78756.02956207407 76984.41708329103 78604.74302901681 83373.9083985452 87989.04442264808 72427.08315693184 72211.84702654855 64319.09268229318 82805.81801853144 1.0115734616030456 0.9510929478946629 0.9296981652432005 0.9492659442290099 1.0068605128674246 1.0625949544143947 0.8746617676154482 0.872062480083078 0.7767460574799099 1.0 16.33744451601323 -7.367490054791228 9.071325827463564 0.8694941953978333 0.9803971283057284 0.39836954297574667 0.06202989757352172 0.35467270818770386 27.905912701753817 0.025916208573486726 0.01744002437071272 4.290520142842816e-08 7.367490054791228 0.1109029329078951 IINEPTAAAIAYGLDKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IINEPTAAAIAYGLDKK 17 1 P11142;E9PKE3;P11142-2;E9PN89;E9PI65;P54652 P11142 HSPA8;HSPA2 Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2 0 ; 133.52 1.3785e-05 16485800.0 54269.0 45883.0 63467.0 75618.0 77678.0 71922.0 66886.0 85165.0 62973.0 56708.0 False True 63455.66983839188 50437.96100981688 64980.293979937895 71381.36861686385 62457.55351618877 68150.28370855504 60550.073867294865 82929.50898977637 63893.86099178862 66988.711499719 0.9472591488591039 0.7529322460550455 0.9700185676837578 1.0655730946125646 0.9323593799300165 1.017339820140307 0.9038847368716573 1.2379624437189578 0.9538004174338633 1.0 16.03163038205283 -5.465103186096364 6.9593644700568005 1.017777218884993 0.8513283513938679 0.3118532613512771 0.09713378038814983 0.27525152245266715 27.843395570154847 0.02461494883392842 0.05112462913286781 3.426863563880434e-06 5.465103186096364 -0.16644886749112509 IINEPTAAAIAYGLDKK ddPTM_PC-9_Lapatinib_30min_R1 4 IINEPTAAAIAYGLDKK 17 1 P11142;E9PKE3;P11142-2;E9PN89;E9PI65;P54652 P11142 HSPA8;HSPA2 Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2 0 ;;; 148.41 2.0227e-05 26648500.0 116390.0 111296.0 112804.0 99753.0 104799.0 98531.0 105788.0 94797.0 106462.0 93823.0 False True 114730.25725668833 111038.30095000584 103529.69055603247 107089.16838625318 98634.92886276139 94317.05881697926 111265.1850153407 99201.61469346279 94471.12846543973 110040.18053871111 1.0426214923950192 1.0090705086670009 0.940835338957043 0.9731824126604391 0.896353753509724 0.8571147225971644 1.0111323379390371 0.9015035617700081 0.8585148443318454 1.0 16.747670886180032 -5.076990261486897 1.0618132533486608 0.9200782532019381 1.07450596666418 0.37998567567806174 0.050507494532755305 1.2078138891249706 1.5532294064580203 0.016768875720684254 0.18845573317557746 8.375480628889593e-06 5.076990261486897 0.15442771346224193 IINEPTAAAIAYGLDKR ddPTM_PC-9_AZD4547_30min_R2 2 IINEPTAAAIAYGLDKR 17 1 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 ; 171.52 7.1207e-06 8055900.0 38408.0 37201.0 51671.0 67455.0 56212.0 47321.0 44192.0 52201.0 42695.0 52247.0 False True 50620.94506397125 49225.49574479518 50985.80877876836 51904.29191936114 48407.934089748655 44362.0103893554 48125.00238875222 44134.53490964603 44951.77053643 50417.84843274914 1.004028268510764 0.9763505836718835 1.0112650651242447 1.029482485524838 0.9601348648250738 0.8798870195448455 0.9545231279146059 0.8753752149601498 0.8915844672822527 1.0 15.621646932461603 -6.525016831921486 5.5480454221156394 0.9147681095657086 1.0029759448195819 0.5375394810137998 0.03694947045172979 0.12002472969542347 12.766464030269955 0.011587400630403076 0.012160785840965518 2.985266916890437e-07 6.525016831921486 0.08820783525387321 IINEPTAAAIAYGLDKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IINEPTAAAIAYGLDKR 17 1 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 ; 203.06 2.4712e-17 7509900.0 33366.0 31688.0 39624.0 44137.0 46412.0 45184.0 41452.0 43003.0 41588.0 36289.0 False True 39014.204791460776 34833.77522130369 40568.78643485682 41664.14698408468 37317.90177132972 42814.471498114 37525.366473508744 41874.2168154448 42196.14582323383 42867.90843643405 0.9101028301698536 0.8125839699633668 0.9463672923304283 0.9719192865652787 0.8705323663426672 0.9987534512349887 0.8753719936943645 0.9768196849990307 0.9843294754117444 1.0 15.387610408041025 -1.5228787454504409 0.1347527600921046 1.020584655401585 0.5029425281020462 0.32602654429863354 0.05012565781154017 92.2831440326323 0.8384148127917483 0.23747969878160816 9.129608015821502 0.02999999998824968 1.5228787454504409 -0.5176421272995387 IINEPTAAAIAYGLDKR ddPTM_PC-9_Lapatinib_30min_R1 2 IINEPTAAAIAYGLDKR 17 1 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 ; 138.77 4.6111000000000006e-05 9220300.0 64570.0 56467.0 55502.0 51275.0 58787.0 58945.0 56607.0 44893.0 65906.0 51296.0 False True 63649.21995931223 56336.25413082216 50938.83980391564 55045.93454838578 55329.26423968886 56424.05975750626 59537.8334798218 46978.892669953966 58482.9722590527 60162.445252376376 1.057956000496807 0.9364023336235144 0.8466883217633776 0.9149550740079253 0.9196644851715596 0.9378618093199519 0.9896179124712371 0.7808674077804099 0.9720843628233788 1.0 15.87657558489254 -4.780864690551949 4.2946326765474465 0.913975976939966 1.0686837153350264 0.29510480344181267 0.06277275124677115 0.2339624920191028 8.828336964762036 0.01500030670894104 0.10959408875213054 1.6562859180444653e-05 4.780864690551949 0.15470773839506036 IINEPTAAAIAYGLDR ddPTM_PC-9_AZD4547_30min_R2 2 IINEPTAAAIAYGLDR 16 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;P17066 A0A0G2JIW1;P17066 HSPA1B;HSPA1A;HSPA6 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 6 0 ; 145.61 0.00013662 10655500.0 13544.400000000001 17404.2 18175.0 26617.0 25708.0 19078.6 18745.7 25576.0 17738.4 22718.6 False True 17851.237458978656 23029.767292319153 17933.98762466597 20480.86187855067 22138.887952381312 17885.612125998112 20414.03098476721 21623.81687801204 18676.015610338658 21923.22872900366 0.8142613334760358 1.0504733393513148 0.8180358763004619 0.9342082834475568 1.009837019265887 0.8158292898863058 0.9311598778222009 0.9863427118928195 0.8518825325044822 1.0 14.420172665452721 -10.76390133904674 3.804466307173853 1.0001000382241891 0.9171169762020571 0.0914709190802141 0.0815925977385098 19287196.00293915 18189643.364573948 14729.269417807895 0.018353384945801073 1.7222597853281563e-11 10.76390133904674 -0.08298306202213201 IINEPTAAAIAYGLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IINEPTAAAIAYGLDR 16 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;P17066 A0A0G2JIW1;P17066 HSPA1B;HSPA1A;HSPA6 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 6 0 ; 131.86 3.9971e-05 11297800.0 17050.0 16346.1 21839.6 21233.2 19988.6 18690.7 20591.6 17857.3 17223.0 16206.5 False True 19936.228247149968 17968.832780388544 22360.33889114423 20043.57264296321 16071.977319365706 17710.52678890312 18641.014577726117 17388.564796373317 17474.853792285183 19144.610159416578 1.0413493970961858 0.9385844177950153 1.1679704472930177 1.046956426694563 0.839504026748774 0.9250920567944769 0.9736951769977537 0.9082746867958802 0.9127819081596655 1.0 14.2246506625214 -6.224698022454343 20.347595502101314 0.9242553703645562 1.0493674217199984 0.45906237152492657 0.06493205027901466 58.86895917448631 32601.1137352265 0.019262771740842347 0.02486468311568839 5.96076468718124e-07 6.224698022454343 0.12511205135544223 IINEPTAAAIAYGLDR ddPTM_PC-9_Lapatinib_30min_R1 2 IINEPTAAAIAYGLDR 16 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;P17066 A0A0G2JIW1;P17066 HSPA1B;HSPA1A;HSPA6 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 6 0 ; 156.2 0.00013432 30083000.0 52726.0 53971.0 38291.3 41753.0 52066.0 46728.0 52999.0 41136.0 44536.0 37746.2 False True 51974.1175712358 53846.03346546833 35143.13712269247 44823.6549039249 49003.58024569449 44729.552368288256 55743.02889390138 43047.328734351155 39519.88669512898 44270.58037635004 1.1740103050241713 1.2162938232956537 0.7938259861049037 1.0124930489474748 1.1069107255678285 1.01036742658525 1.2591438472236538 0.9723687462057227 0.8926896001625734 1.0 15.434060666484067 IIPELVGS(ph)PTQSTSSR ddPTM_PC-9_AZD4547_30min_R2 3 IIPELVGSPTQSTSSR 16 0 Q9NSI6-3;Q9NSI6-2;Q9NSI6;H7C409 Q9NSI6-3 BRWD1 Bromodomain and WD repeat-containing protein 1 1 IIPELVGS(0.634)PT(0.27)QS(0.011)T(0.001)S(0.001)S(0.082)R;IIPELVGS(0.485)PT(0.485)QS(0.004)T(0.002)S(0.001)S(0.023)R;IIPELVGS(0.661)PT(0.247)QS(0.012)T(0.012)S(0.006)S(0.063)R 163.34 3.1438e-05 29909500.0 21748.0 18835.8 24975.5 35690.0 28297.2 29055.5 20294.2 30491.5 21256.0 27323.0 True False 28663.411613498403 24924.10399585531 24644.308551298196 27462.2219050033 24368.62222522656 27238.654991820058 22100.34448492523 25779.739299964975 22379.54876501594 26366.43008647394 1.0871176537548335 0.9452968761456049 0.9346850700103235 1.0415601131793533 0.9242291104751317 1.0330808874195514 0.838200105681458 0.9777485695035393 0.8487894907129166 1.0 14.686414628598342 -7.245661628691194 24.926796158722354 0.9143302470499799 0.9883491025541992 0.24324234228210728 0.06699615857261562 1152.1069186636716 1820181.9694105582 0.024000455394887536 0.018528790092045822 5.679869680233925e-08 7.245661628691194 0.07401885550421927 IIPELVGS(ph)PTQSTSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IIPELVGSPTQSTSSR 16 0 Q9NSI6-3;Q9NSI6-2;Q9NSI6;H7C409 Q9NSI6-3 BRWD1 Bromodomain and WD repeat-containing protein 1 1 IIPELVGS(0.716)PT(0.282)QS(0.001)TSS(0.001)R;IIPELVGS(0.972)PT(0.027)QS(0.001)TSSR;IIPELVGS(0.716)PT(0.281)QS(0.002)TSSR 199.33 4.0389e-12 31216700.0 45522.5 47617.2 57405.3 54152.9 61825.1 50879.4 52336.4 47235.0 45416.1 44006.7 True False 53228.56013964135 52344.320924888336 58774.06006281257 51118.8885790706 49710.91547019387 48211.19469593531 47378.71730927686 45995.1312996194 46080.224543680146 51984.76635315449 1.0239261205491863 1.0069165372272955 1.1306016009293096 0.9833436247803516 0.9562592843543166 0.9274100487134305 0.9113961768609905 0.8847809565432119 0.886417844616973 1.0 15.665801296522506 -6.230916335865624 2.0987490229284194 0.9159644340419918 1.0487123485088554 0.6062189776148191 0.04473249703193738 0.20746060687835277 1.7941090053090503 0.014976940270352925 0.01980162116808338 5.87602539606473e-07 6.230916335865624 0.13274791446686363 IIPELVGS(ph)PTQSTSSR ddPTM_PC-9_Lapatinib_30min_R1 3 IIPELVGSPTQSTSSR 16 0 Q9NSI6-3;Q9NSI6-2;Q9NSI6;H7C409 Q9NSI6-3 BRWD1 Bromodomain and WD repeat-containing protein 1 1 IIPELVGS(0.493)PT(0.493)QS(0.004)T(0.001)SS(0.009)R;IIPELVGS(0.878)PT(0.121)QSTSSR;IIPELVGS(0.931)PT(0.066)QS(0.001)TSS(0.001)R 191.15 1.672e-08 33797600.0 68279.4 57872.9 65653.8 57753.4 64213.9 58185.8 51165.7 55241.2 69441.7 48402.1 True False 67305.72323509159 57738.89885575038 60255.99799499686 62000.77769569459 60436.964651384806 55697.32897172459 53814.80959030718 57807.907819915345 61620.44449248111 56768.33849325574 1.1856208059196187 1.0170968604728488 1.0614367021179503 1.0921717869734813 1.064624511752531 0.9811336820848053 0.9479722503539637 1.0183124846393576 1.0854720452986628 1.0 15.79279889670181 -6.640093642580899 5.296295277994978 1.0043562458565045 1.0814807244346698 0.3688189124924691 0.05105679109469976 0.252393083738106 10.70704974371936 0.017364891600419045 0.01730091759549693 2.2903737491093028e-07 6.640093642580899 0.07712447857816529 IIPELVGSPT(ph)QSTSSR ddPTM_PC-9_AZD4547_30min_R2 1 IIPELVGSPTQSTSSR 16 0 Q9NSI6-3;Q9NSI6-2;Q9NSI6;H7C409 Q9NSI6-3 BRWD1 Bromodomain and WD repeat-containing protein 1 1 IIPELVGS(0.362)PT(0.484)QS(0.002)T(0.001)S(0.005)S(0.145)R 172.42 4.5916000000000006e-05 12652000.0 25873.0 27178.0 35706.0 47724.0 49936.0 42709.0 33802.0 43193.0 35510.0 39537.0 True False 34100.075808168294 35962.757005242966 35232.51511011404 36721.9691284499 43003.248358103076 40038.39947843409 36810.31251684926 36518.51432639875 37386.986104898206 38152.821664126204 0.8937759861738203 0.9425975704192153 0.923457651973405 0.9624968095866501 1.1271315326734421 1.0494217133114647 0.9648123234738557 0.9571641816661718 0.9799271580495424 1.0 15.21950213779684 -6.006029650810558 23.396529987049746 1.0134725960926807 0.9256704079510213 0.4402692559191438 0.04729126676232807 128.5638338748861 498870.500503763 0.015110244089254597 0.021549441148649623 9.862121511631658e-07 6.006029650810558 -0.08780218814165941 IIPELVGSPTQSTSS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IIPELVGSPTQSTSSR 16 0 Q9NSI6-3;Q9NSI6-2;Q9NSI6;H7C409 Q9NSI6-3 BRWD1 Bromodomain and WD repeat-containing protein 1 1 IIPELVGS(0.149)PT(0.104)QS(0.033)T(0.01)S(0.01)S(0.694)R 125.39 3.1936999999999996e-05 9124200.0 8693.4 11259.0 17707.0 14962.0 19011.0 14628.0 14808.0 14175.0 17499.0 11687.0 True False 10165.020917523378 12376.719111861228 18129.20203417145 14123.727647458485 15285.931021605384 13860.881928877736 13405.279039364024 13802.92126965397 17754.88977014449 13805.760585758911 0.7362883670465012 0.8964894787925132 1.313162134136406 1.0230314773115483 1.1072139725045873 1.0039926335659974 0.9709917071278205 0.9997943383062958 1.2860493748138175 1.0 13.752982750494338 -5.0183083241243525 9.690082607380786 1.0809767132479953 0.7755349264823013 0.49279080500561756 0.11520653969000105 0.23741706177091668 125.88546298944593 0.028853746743763755 0.0846658974586192 9.587197539224495e-06 5.0183083241243525 -0.305441786765694 IIPELVGSPTQSTSS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 IIPELVGSPTQSTSSR 16 0 Q9NSI6-3;Q9NSI6-2;Q9NSI6;H7C409 Q9NSI6-3 BRWD1 Bromodomain and WD repeat-containing protein 1 1 IIPELVGS(0.337)PT(0.151)QS(0.007)T(0.006)S(0.007)S(0.492)R 133.87 3.5042000000000003e-06 7118100.0 8194.8 7516.4 7420.9 8677.6 8924.2 6816.6 5601.1 6379.6 9433.2 7817.7 True False 8077.940649257727 7498.996237606238 6810.782247502391 9315.779651625002 8399.296101652266 6525.0699082707115 5891.097551607218 6676.019505874819 8370.733680000241 9168.979028569533 0.8810076480803097 0.8178660038637005 0.7428070482308599 1.0160105746341064 0.9160557653672214 0.711646289945621 0.6425031111153383 0.7281093658381238 0.9129406506349239 1.0 13.162545382449315 -6.755584257776315 24.99892812203191 0.7722631693267868 0.8721069305079541 0.07275505596972254 0.11683124454348265 294.8842964114071 1259032.0295638482 0.039895118033225256 0.038887061958027845 1.755560263682088e-07 6.755584257776315 0.09984376118116722 IIPGFMCQGGDFTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IIPGFMCQGGDFTR 14 0 P62937;F8WE65;C9J5S7;P0DN26;A0A0H2UH34;A0A0B4J2A2;A0A075B767;A0A075B759;Q9Y536;F5H284 P62937 PPIA;PPIAL4C;PPIAL4E;PPIAL4A;PPIAL4D Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase;Peptidyl-prolyl cis-trans isomerase A-like 4A/B/C;Peptidyl-prolyl cis-trans isomerase A-like 4D 0 93.44200000000001 0.021833 0.0 8104.5 5268.5 5881.0 7953.1 6238.6 6037.7 6944.9 9563.0 5788.9 4328.5 False True 9476.431778828566 5791.521861696499 6021.2253438167 7507.513591298089 5016.191114164816 5721.0723832366075 6287.0287952781755 9311.981382836047 5873.5517109771645 5113.222785612852 1.8533187729454186 1.1326558815297834 1.177579306882287 1.4682547399307706 0.9810233828025144 1.1188779803090276 1.2295628527996234 1.8211569832312613 1.148698571770364 1.0 12.320017170983581 -4.754519938433812 24.971892619734714 1.2509338777851873 1.8533198224791099 0.382994286669721 0.23577965456642627 268.91209981932275 970402.5623502847 0.05965440965625484 0.5761199688752001 1.759867866517794e-05 4.754519938433812 0.6023859446939226 IIPS(ph)PDDSKFLLK ddPTM_PC-9_Lapatinib_30min_R1 1 IIPSPDDSKFLLK 13 1 A0A3B3ITL0;Q9Y2H2;A0A3B3ISJ5;A0A3B3ITR9;A0A3B3ISI3;Q9Y2H2-3;Q9Y2H2-2 A0A3B3ITL0 INPP5F Phosphatidylinositide phosphatase SAC2 1 IIPS(0.997)PDDS(0.003)KFLLK 54.898 0.037518 796840.0 10868.0 5949.0 5890.9 4414.5 7252.5 6636.6 6954.7 6518.7 9035.4 5213.7 True False 10713.020327052885 5935.2254560054735 5406.572941531597 4739.157056340301 6825.922208963606 6352.768088670217 7314.780336391547 6821.582599684337 8017.738105019948 6114.881098181438 1.7519588942193711 0.9706199287784363 0.8841664874137143 0.7750203119648106 1.1162804475451913 1.0389029625710182 1.1962260948241428 1.1155707674697177 1.3111846291507483 1.0 12.57810873096475 -7.258528742495862 23.252384676728852 1.1653762682798658 1.0616788296321717 0.008373711499575998 0.25573498045138243 430.90560983150084 3442445.245631742 0.1027130329050334 0.07592477615798852 5.514057080181141e-08 7.258528742495862 -0.1036974386476941 IIPTLEEGLQLPS(ph)PTATSQLPLESDAVECLNYQHYK ddPTM_PC-9_Lapatinib_30min_R1 1 IIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYK 36 0 P61978;P61978-2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 IIPTLEEGLQLPS(0.405)PT(0.405)AT(0.095)S(0.095)QLPLESDAVECLNYQHYK 137.51 2.0016e-22 41629000.0 67741.0 63080.0 84717.0 63927.0 86092.0 86736.0 82719.0 96942.0 104770.0 78620.0 True False 66775.000917822 62933.942135623634 77751.8952770768 68628.40483422058 81028.23782338432 83026.50347149148 87001.78507282457 101446.27922417036 92969.69932298962 92209.36224543514 0.7241672569005076 0.6825114131915515 0.8432104222792836 0.7442672106499474 0.8787419829204561 0.9004129456019715 0.9435244204514778 1.100173309453645 1.0082457687488464 1.0 16.492625618049452 -6.720641673455616 0.7536551022187871 1.0457373679486632 0.7187998856081511 0.8487760998151741 0.05021996595987059 0.23626891744882947 0.29588777306712766 0.034360392823957996 0.03529339993076615 1.9026474638307824e-07 6.720641673455616 -0.3269374823405121 IIPTLEEGLQLPSPT(ph)ATSQLPLESDAVECLNYQHYK ddPTM_PC-9_Lapatinib_30min_R1 1 IIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYK 36 0 P61978;P61978-2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 IIPTLEEGLQLPS(0.172)PT(0.749)AT(0.064)S(0.015)QLPLESDAVECLNYQHYK 126.37 6.5727e-22 12067000.0 12996.0 16861.0 18679.0 17136.0 22332.0 21865.0 19968.0 18749.0 22686.0 19273.0 True False 12810.674656825478 16821.959390436758 17143.28472302514 18396.238604020262 21018.475666401275 20929.884919804445 21001.845335825634 19620.146986589607 20130.863785829355 22604.312370341744 0.5667358708789512 0.7441924848157827 0.7584077074389659 0.8138375679216531 0.9298436210773133 0.925924424370712 0.9291079061259724 0.867982474544656 0.8905762518236252 1.0 14.464310410677395 -4.067667157772751 0.5143678012709403 0.9303995072048644 4.98772882826022e-13 0.8855905289472138 0.04051310397709217 2.8394858643793564 0.3320191508900256 0.024172828322746313 1.8612198784106166 8.55722285101577e-05 4.067667157772751 -0.9303995072043656 IIS(ph)IFSGTEK ddPTM_PC-9_AZD4547_30min_R2 2 IISIFSGTEK 10 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 IIS(0.629)IFS(0.371)GTEK;IIS(0.826)IFS(0.174)GTEK 158.56 0.00016698 49160000.0 61222.0 71015.0 70562.0 131413.0 89945.0 82163.0 146167.0 232530.0 180218.0 116186.0 True False 80689.32250329219 93969.20997598545 69626.3017756083 101117.76316061085 77457.68931371329 77025.33462142825 159175.57983700122 196597.83150782532 189743.95555766125 112118.36350426612 0.7196798096345917 0.8381250585450251 0.621007117830069 0.9018840446842885 0.690856402936759 0.6870001685183126 1.4197101604229585 1.7534846689083607 1.6923539519058488 1.0 16.77466306628955 -7.3191604050619725 4.656224754142677 1.5457244201318188 0.7457303643841526 0.7452547604440889 0.20590775038871958 0.09733823118230679 4.443835962740822 0.08404227877742874 0.05635333587447257 4.795562935780686e-08 7.3191604050619725 -0.7999940557476661 IIS(ph)NASCTTNCLAPLAK ddPTM_PC-9_AZD4547_30min_R2 3 IISNASCTTNCLAPLAK 17 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 IIS(0.501)NAS(0.001)CT(0.313)T(0.186)NCLAPLAK;IIS(0.996)NASCTT(0.003)NCLAPLAK;IIS(1)NASCTTNCLAPLAK 244.18 3.4277e-47 110565000.0 257782.0 242302.0 325290.0 432535.0 360294.0 343949.0 242797.0 369513.0 300866.0 317502.0 True False 339751.3138013088 320621.38302613853 320976.44205928996 332820.73834913445 310273.3972271381 322441.81465751876 264405.46263988735 312413.25641401554 316769.16252988717 306386.35162008734 1.108898330505901 1.0464610493606528 1.0476199098362384 1.0862779513162688 1.012686745302123 1.052402670525415 0.862980551326074 1.0196709310387344 1.033887968099422 1.0 18.224992506397534 -6.731595294815362 2.0087481083413414 0.9821857516802113 1.066522450104442 0.35083154812651984 0.05070710209681155 0.3723836356230748 3.094028787687418 0.02024059045806493 0.01897593118420784 1.8552596754870035e-07 6.731595294815362 0.08433669842423064 IIS(ph)NASCTTNCLAPLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IISNASCTTNCLAPLAK 17 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 IIS(0.997)NASCT(0.001)T(0.003)NCLAPLAK 249.89 1.1062999999999999e-47 17205000.0 46821.0 51411.0 51318.0 51659.0 58216.0 56224.0 60819.0 50809.0 51333.0 48009.0 True False 54746.87054309732 56514.74431653764 52541.61574459875 48764.713710737735 46808.992707052705 53275.51446330471 55057.78402857109 49475.31758658543 52083.64801250511 56712.65166096513 0.9653378732911401 0.9965103493024695 0.9264531670763462 0.8598559983098463 0.8253712590778217 0.9393938195976441 0.9708201330051179 0.8723858986942573 0.9183779366175162 1.0 15.791382992185504 -5.398559051323368 4.7939955426312295 0.9060727076355938 0.9800160610042148 0.2209221273183073 0.04961450630970622 0.30146564170255863 10.348474058034695 0.013502831128254983 0.029151893858303874 3.994302468067537e-06 5.398559051323368 0.07394335336862101 IIS(ph)NASCTTNCLAPLAK ddPTM_PC-9_Lapatinib_30min_R1 3 IISNASCTTNCLAPLAK 17 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 IIS(0.869)NAS(0.044)CT(0.055)T(0.033)NCLAPLAK;IIS(0.661)NAS(0.203)CT(0.135)T(0.002)NCLAPLAK;IIS(0.742)NAS(0.243)CT(0.013)T(0.003)NCLAPLAK 173.77 6.6565e-06 98970600.0 361748.0 365505.0 413602.0 351433.0 421392.0 402556.0 379389.0 373518.0 388413.0 295554.0 True False 356589.4071835409 364658.69562906015 379597.24010989035 377278.55516612023 396606.5510485475 385339.61828386935 399031.90605536615 390873.0098744994 344665.8377697847 346640.11509904935 1.0287020793356494 1.0519806558593547 1.0950759118038713 1.088386885223357 1.1441449900719676 1.1116417330226247 1.1511417423264654 1.1276046621517273 0.9943045330206501 1.0 18.403079095194542 -1.7708637479996643 20.428140397555616 1.0874701668487898 0.0902418706303284 0.0 0.055284621803880406 0.0 0.0 0.012722135434208505 0.0 0.016948694515309698 1.7708637479996643 -0.9972282962184614 IIS(ph)PGSSTPSSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IISPGSSTPSSTR 13 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 IIS(0.584)PGS(0.166)S(0.166)T(0.055)PS(0.014)S(0.014)T(0.001)R 71.268 0.026289999999999997 11562000.0 64545.0 44973.0 47611.0 52245.0 65250.0 46427.0 38025.0 61249.0 37681.0 33308.0 True False 75471.19367814055 49437.622223797356 48746.226805722974 49317.88203057537 52464.730901044226 43992.28638993752 34422.99672284015 59641.27864867983 38232.01333955163 39346.47673401707 1.9181182139465054 1.2564688461941997 1.2388968683333044 1.2534256209003207 1.3334035282423582 1.1180743497651953 0.874868592569044 1.5157971843795826 0.9716756495886726 1.0 15.263946835461827 -2.622196157909651 1.2737452351379293 1.168894214267426 199.99996941875787 0.6115346728276336 0.1787185840149823 259.374669133535 2.1197584027216902 0.05038561625968919 148932.58342579028 0.002386733023052993 2.622196157909651 198.83107520449045 IIS(ph)PGSSTPSSTR ddPTM_PC-9_Lapatinib_30min_R1 2 IISPGSSTPSSTR 13 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 IIS(0.817)PGS(0.091)S(0.091)T(0.002)PSSTR;IIS(0.302)PGS(0.224)S(0.168)T(0.302)PS(0.004)STR 74.78 0.019098 35361000.0 157291.0 197041.0 121981.0 150553.0 160769.0 142835.0 163028.0 176829.0 134032.0 144430.0 True False 155048.00149636317 196584.76367066285 111952.19304027648 161625.1698500856 151312.88350401504 136726.28001464752 171468.7921378696 185045.12088600223 118935.90474046889 169394.53305912245 0.9153069977898755 1.1605142156627357 0.6608961400259753 0.9541345103131211 0.8932571835196328 0.8071469459225524 1.0122451359042572 1.0923913395801113 0.7021236316933417 1.0 17.370027789155543 -7.293749807433092 24.953584748181044 0.959389282318452 0.9019349383960481 0.027934717415240007 0.15008156622387306 2956.112014909248 2283014.3832732984 0.06191516021602706 0.04174668094657857 5.084522723086416e-08 7.293749807433092 -0.057454343922403894 IIS(ph)PVESDSSVR ddPTM_PC-9_AZD4547_30min_R2 4 IISPVESDSSVR 12 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5 Q8NEV8-2 EXPH5 Exophilin-5 1 IIS(1)PVESDSSVR;IIS(0.99)PVES(0.004)DS(0.001)S(0.005)VR;IIS(1)PVESDSSVR;IIS(0.972)PVES(0.028)DSSVR 215.02 9.3576e-11 54100000.0 61058.0 64572.2 99240.0 133216.0 112251.0 86287.0 86930.0 112129.0 100013.0 90926.0 True False 80473.17391470422 85443.90087180643 97924.01275773579 102505.1093666832 96666.88624329973 80891.46024949425 94666.60159427582 94802.03951808783 105299.48299941374 87742.7084157203 0.9171494175154314 0.9738005859926018 1.1160359023085658 1.1682464699063018 1.1017084836872955 0.921916609483204 1.0789113227021723 1.0804549030891637 1.2000938300252868 1.0 16.4209916192736 -5.097741791508439 3.979654164517885 1.0836974786448585 0.9271912009513783 0.36314658882379736 0.07457604574543736 0.24684305514508315 6.786768788270931 0.02022284531089068 0.0650733842904543 7.984692737020982e-06 5.097741791508439 -0.15650627769348024 IIS(ph)PVESDSSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IISPVESDSSVR 12 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5 Q8NEV8-2 EXPH5 Exophilin-5 1 IIS(0.911)PVES(0.013)DS(0.038)S(0.038)VR;IIS(0.851)PVES(0.122)DS(0.006)S(0.021)VR;IIS(1)PVESDSSVR 158.86 8.5614e-05 30411900.0 52680.2 61181.5 67181.0 70061.0 73028.0 73847.0 77054.0 71358.0 63338.0 53021.0 True False 61597.9173786223 67255.19498555257 68782.84982536128 66135.70931082673 58718.6876358844 69974.33331978635 69754.88729734972 69484.92811005053 64264.19842627643 62633.28758599495 0.9834693300115996 1.073793147026041 1.0981836093295125 1.0559194936082987 0.9374996890473642 1.1172067764080276 1.1137031119686458 1.1093929568146705 1.0260390425465413 1.0 15.934641986729893 IIS(ph)PVESDSSVR ddPTM_PC-9_Lapatinib_30min_R1 3 IISPVESDSSVR 12 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5 Q8NEV8-2 EXPH5 Exophilin-5 1 IIS(1)PVESDSSVR;IIS(1)PVESDSSVR;IIS(0.988)PVES(0.011)DS(0.001)SVR 174.46 0.00088038 38981800.0 83720.0 82786.0 95762.0 71895.0 90106.0 88308.0 84071.0 75628.0 100113.0 71822.0 True False 82526.13744763235 82594.31410335677 87888.8180120097 77182.39813468921 84806.142235212 84531.27269600242 88423.78501743778 79141.95297358789 88837.2197033737 84236.3370032004 0.9796976030011482 0.9805069527206383 1.043359922080545 0.9162601423629901 1.0067643638396806 1.0035012882004926 1.0497107087417428 0.9395227260485108 1.0546187413158588 1.0 16.36215508203113 -6.468596735436492 24.99997348444653 1.007864753785394 0.9816478400344745 0.10693837979244558 0.04096044844969583 812.5830636698844 374240.1036566213 0.012201021407880427 0.013834480980700488 3.399407784265026e-07 6.468596735436492 -0.0262169137509195 IISGS(ph)PLGSLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IISGSPLGSLAR 12 0 Q9BXL7 Q9BXL7 CARD11 Caspase recruitment domain-containing protein 11 1 IIS(0.01)GS(0.99)PLGSLAR;IIS(0.314)GS(0.682)PLGS(0.004)LAR 131.79 0.00010607 7073100.0 30173.0 22979.0 27459.0 31341.0 34878.0 25556.0 27861.0 27482.0 27455.0 25681.0 True False 35280.69295608541 25260.203257079593 28113.726698837396 29585.06537889294 28043.90627381793 24215.79837123321 25221.804383827726 26760.62661958592 27856.477435242978 30336.762009315848 1.1629683136668105 0.8326598352626645 0.926721404552147 0.9752215931880905 0.9244198924462069 0.7982327963609628 0.831394081414575 0.882118751215711 0.9182416180965121 1.0 14.88877948746808 -4.75338849901181 24.9987779469013 0.8939105740992471 1.1629688049162772 0.625892204151969 0.0611711439848721 202.34141227323684 628240.3953413081 0.015847640690414153 0.1717886216039181 1.764458714364586e-05 4.75338849901181 0.26905823081703006 IISIFS(ph)GTEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IISIFSGTEK 10 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 IIS(0.007)IFS(0.927)GT(0.066)EK;IIS(0.002)IFS(0.957)GT(0.041)EK 182.41 0.00012776 33335000.0 251040.0 163607.0 123349.0 163024.0 261050.0 222740.0 249970.0 484520.0 276090.0 220320.0 True False 293536.11373398965 179848.82171900503 126290.10796368748 153890.29381093883 209899.1264631047 211059.12228863974 226291.03197392123 471801.863391376 280127.29393903597 260262.2719478397 1.1278473500485637 0.6910291698177803 0.485241702604509 0.5912892892973003 0.8064907944289809 0.8109478208617922 0.869473052241983 1.8127939169221263 1.076326936833847 1.0 17.989606665861125 -7.547381060473444 22.868950209958985 1.3349644165075425 0.7413753706594729 0.47370160661280947 0.25622675514359344 68.01772908522506 63481.50553541364 0.11783395425039768 0.06803846079169389 2.8354300618051758e-08 7.547381060473444 -0.5935890458480696 IISIFS(ph)GTEK ddPTM_PC-9_Lapatinib_30min_R1 1 IISIFSGTEK 10 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 IIS(0.002)IFS(0.993)GT(0.005)EK 162.49 0.00063314 15418000.0 37543.0 37563.0 39309.0 35566.0 66918.0 63594.0 89789.0 46703.0 64702.0 97105.0 True False 37007.629935457 37476.02518136382 36077.16575712804 38181.642284697955 62982.014805849925 60874.23286485453 94437.83507904885 48872.9918776838 57414.57941773474 113889.46986572052 0.32494338571502906 0.3290561034795342 0.3167734980210569 0.33525173424474963 0.5530099918816711 0.5345027326637597 0.8292060292351365 0.4291265200839611 0.5041254427246737 1.0 16.797274837156294 -6.416134840759329 1.806943831331513 0.6393676932044703 0.31762856067553963 0.5087155909627157 0.15445069369199071 0.31973278459498927 2.0774015142527684 0.055680981985839234 0.06558133110857417 3.8358812966822784e-07 6.416134840759329 -0.32173913252893066 IISIFSGT(ph)EK ddPTM_PC-9_Lapatinib_30min_R1 1 IISIFSGTEK 10 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 IISIFS(0.066)GT(0.934)EK 169.89 0.0032961999999999996 12989000.0 49635.0 59981.0 50878.0 41065.0 116060.0 77691.0 136620.0 71547.0 103540.0 139570.0 True False 48927.19579805581 59842.11767972168 46695.00723475952 44085.05708882421 109233.57898273917 74368.33703656659 143693.51511320594 74871.33481516484 91878.23487546368 163694.48853466514 0.2988933606502862 0.36557197627975774 0.2852570520410102 0.26931302014782516 0.6673015075862317 0.45431179572559527 0.8778152300636337 0.4573845795627355 0.5612787314828066 1.0 17.3206462226535 -6.262829444113479 24.827735737060078 0.6421893666885464 0.30770965143363616 0.5425886550342939 0.1629662995817562 93.30822504304146 1666562.3421289925 0.04721720804870606 0.05650605338321567 5.459722329050846e-07 6.262829444113479 -0.33447971525491027 IISNAS(ph)CTTNCLAPLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IISNASCTTNCLAPLAK 17 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 IIS(0.141)NAS(0.854)CT(0.005)TNCLAPLAK 169.58 1.6028e-05 50659000.0 216000.0 207620.0 225980.0 250460.0 263340.0 260770.0 259980.0 221630.0 214930.0 204410.0 True False 252564.5338055366 228231.14148722164 231368.22023392303 236427.53820227538 211740.4174020076 247094.76214065103 235352.81230779766 215812.44733639585 218072.94464238844 241467.9148913304 1.0459548380131583 0.9451820611029593 0.9581737612553923 0.9791261017376848 0.8768884159922393 1.0233026704680532 0.9746752996716571 0.8937520640517376 0.9031135450874681 1.0 17.8814719777738 -4.760058123743565 24.894345793284362 0.9490174966483367 1.045954962515447 0.28896667367616 0.044883122972275875 43.679150498787145 786926.0418325347 0.01118143942707489 0.0677606468109279 1.7375682659720784e-05 4.760058123743565 0.09693746586711027 IISNASCT(ph)TNCLAPLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IISNASCTTNCLAPLAK 17 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 IIS(0.01)NAS(0.005)CT(0.779)T(0.206)NCLAPLAK 124.38 9.9409e-05 38975000.0 215760.0 187760.0 217570.0 232660.0 303750.0 205790.0 283050.0 182000.0 219860.0 202000.0 True False 252283.90654575205 206399.5719373893 222757.69393881987 219624.81449389717 244232.3679876197 194998.01012740954 256237.45489546165 177222.69284493948 223075.03656574507 238621.00096887935 1.0572577665896834 0.8649681758912229 0.9335209098710957 0.9203918079387337 1.023515813763065 0.8171871265967949 1.0738260834337872 0.7426952871933206 0.9348508122084286 1.0 17.864361494252677 -7.7563529868626295 24.999980044318693 0.8790798041343706 0.9473687014107574 0.07211970639309018 0.09739349967508955 294.5306447227111 1447659.0885287032 0.043812448817426686 0.02429728421307841 1.752455557997751e-08 7.7563529868626295 0.06828889727638676 IISNASCT(ph)TNCLAPLAK ddPTM_PC-9_Lapatinib_30min_R1 1 IISNASCTTNCLAPLAK 17 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 IISNASCT(0.5)T(0.5)NCLAPLAK 235.37 6.506899999999999e-37 17845000.0 42309.0 59361.0 56688.0 41303.0 58641.0 54572.0 55560.0 57590.0 55805.0 39817.0 True False 41705.66590147963 59223.55325162894 52027.33146200805 44340.56040276891 55191.85167264187 52238.08277354536 58436.624942832146 60265.84164263132 49519.653247298185 46699.31539718246 0.8930680363677428 1.2681888963023666 1.1140919523018757 0.9494905872955076 1.1818556911001696 1.1186048945098042 1.251337936023744 1.2905080327209117 1.0603935587947804 1.0 15.511113780012666 IISNASCTT(ph)NCLAPLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IISNASCTTNCLAPLAK 17 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 IIS(0.002)NASCT(0.087)T(0.912)NCLAPLAK 145.79 0.00023672 13080000.0 52510.0 55119.0 55485.0 57749.0 69863.0 59814.0 62115.0 55986.0 53210.0 42936.0 True False 61398.90588022551 60590.85005121935 56807.97282803426 54513.51075478413 56173.84666574175 56677.24854347092 56231.01752634365 54516.42682207033 53988.095586569994 50719.956918811 1.2105472798115469 1.1946155661805666 1.120031961363227 1.0747941060369115 1.1075294633167958 1.1174545876329496 1.1086566500116388 1.0748515995259313 1.064434965372514 1.0 15.630265899611862 -1.5228787452803376 0.16283564777908985 1.0082887457800593 1.7696480971740263 0.8124964996519135 0.025253212925717264 30.908794161550507 0.3242867669549422 0.08315853978929955 5.667514782051906 0.029999999999999995 1.5228787452803376 0.7613593513939669 IISNASCTT(ph)NCLAPLAK ddPTM_PC-9_Lapatinib_30min_R1 1 IISNASCTTNCLAPLAK 17 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 IISNASCT(0.24)T(0.76)NCLAPLAK 117.13 0.00031865 16448000.0 40189.0 62396.0 62267.0 48322.0 58033.0 65284.0 63104.0 62569.0 53471.0 38245.0 True False 39615.89749024003 62251.52589559882 57147.64761757085 51875.76107746654 54619.61303726783 62491.95550443699 66371.21634975665 65476.18415936445 47448.53290540781 44855.5972917408 0.8831873808875677 1.3878206880339794 1.2740360416088667 1.1565058590139061 1.2176766409333906 1.39318076845548 1.479664085578401 1.459710451150775 1.0578062888518138 1.0 15.453000402178628 -4.752842038705557 24.983530787288885 1.2893742612628525 0.8831866111369626 0.34716815295047365 0.15687038890639518 359.8908491406729 1045749.1913720351 0.03898070761588505 0.44564394521006506 1.7666802795949495e-05 4.752842038705557 -0.40618765012588987 IISNASCTTNCLAPLAK ddPTM_PC-9_AZD4547_30min_R2 2 IISNASCTTNCLAPLAK 17 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 195.2 1.9033e-11 64645000.0 90034.0 84055.0 109263.0 157003.0 121591.0 121238.0 113202.0 145611.0 95149.0 123160.0 False True 118662.93917646317 111224.13496488688 107814.10122882402 120808.38402216948 104710.1884634355 113656.9686943361 123276.75869866798 123110.16575790655 100178.38188946656 118848.20588698628 0.9984411484452758 0.9358503490633322 0.9071580039781612 1.016493123480948 0.8810413895772669 0.9563204412392513 1.0372622605333466 1.0358605318364924 0.8429103421613868 1.0 16.858760599193943 -7.016869220799104 24.74069433483923 0.9841101898703238 0.9456907689296585 0.04996454907692982 0.06264970040314954 1834.3113086955955 2690228.792483538 0.02311229974484095 0.018370332137340416 9.619018925219558e-08 7.016869220799104 -0.038419420940665305 IISNASCTTNCLAPLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IISNASCTTNCLAPLAK 17 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 114.69 0.0025675 2916200.0 27200.0 30072.9 34632.0 33927.0 43138.0 37429.0 37998.0 33031.0 33052.0 31228.0 False True 31804.42277551199 33058.33876712776 35457.75822259139 32026.180182818054 34685.418568724046 35466.15735001127 34398.55435830324 32163.971249237416 33535.32297175926 36889.389199288016 0.8621563941786771 0.8961476317359519 0.9611912528840607 0.8681678086292677 0.9402546185121843 0.9614189369851585 0.9324782845406167 0.8719030579627541 0.9090777510733767 1.0 15.170918281174933 -4.977168671827646 4.633366852320418 0.9255734234680246 0.8668455033805379 0.2346808365507015 0.03854340208490172 0.28977996185494603 15.726413856458139 0.009619908342735963 0.039417844311447764 1.0539774718168315e-05 4.977168671827646 -0.05872792008748673 IISNASCTTNCLAPLAK ddPTM_PC-9_Lapatinib_30min_R1 2 IISNASCTTNCLAPLAK 17 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 143.93 0.00019446 240470000.0 308069.0 329120.0 321720.0 319280.0 331510.0 319100.0 307800.0 274870.0 296259.0 293446.0 False True 303675.8795670651 328357.94286107237 295269.4234751129 342760.916286857 312011.2335737371 305452.83685843146 323736.37792303367 287641.4636622695 262891.19167442585 344167.7501077835 0.882348446279358 0.9540636586613361 0.857922984889325 0.9959123601194885 0.9065673163044013 0.8875115020590174 0.9406354250845662 0.8357594910394378 0.7638460942145098 1.0 18.392752391863233 -7.765620266546961 24.99877866646679 0.8498520814725705 0.9183408822379665 0.09645610544995409 0.06630639226117245 179.96361431484794 1076025.1954039584 0.03250173066535398 0.016499277411766714 1.7154565933084474e-08 7.765620266546961 0.06848880076539599 IISPGSST(ph)PSSTR ddPTM_PC-9_AZD4547_30min_R2 1 IISPGSSTPSSTR 13 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 IIS(0.001)PGS(0.146)S(0.146)T(0.699)PS(0.004)S(0.003)T(0.001)R 96.23 0.008108 4691400.0 14632.0 18565.0 31450.0 25656.0 23265.0 24598.0 21502.0 28067.0 17598.0 22101.0 True False 19284.671635493305 24565.773191637956 31032.952450935045 19741.405581248673 20035.056333131764 23059.883171474907 23415.636345106588 23729.890065497486 18528.194352970946 21327.250717020856 0.9042267984453614 1.1518490365958187 1.4550845236778813 0.9256423081993147 0.9394111129918018 1.0812403097540966 1.0979209958093208 1.1126558401903688 0.8687568125311136 1.0 14.380410380269629 IISPGSSTPS(ph)STRSPPPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IISPGSSTPSSTRSPPPGR 19 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 IISPGSST(0.002)PS(0.33)S(0.33)T(0.33)RS(0.007)PPPGR;IISPGSS(0.006)T(0.004)PS(0.31)S(0.263)T(0.224)RS(0.192)PPPGR 74.726 0.0020101 16576700.0 54230.0 45989.0 37462.0 53913.0 50994.0 40827.0 46311.0 43510.0 45215.0 38833.0 True False 63410.06790867705 50554.48398928728 38355.236155426166 50892.42939830429 41002.09176349191 38685.96024817411 41924.08681739515 42367.908602655705 45876.183836623975 45873.115498141146 1.3822925960031323 1.1020503717768162 0.836115788930455 1.1094173318218714 0.8938152841429177 0.8433253296201721 0.9139140946093793 0.9235890813732179 1.0000668875102445 1.0 15.48536127173244 -4.865232173583996 2.826126564520915 0.9373884083276882 1.4227188645050997 0.750455047948108 0.07810515119241716 0.16439990322967682 2.0732992333612303 0.019971779195884685 0.1705409129842001 1.3638538261789817e-05 4.865232173583996 0.48533045617741144 IISPGSSTPSST(ph)RSPPPGR ddPTM_PC-9_Lapatinib_30min_R1 1 IISPGSSTPSSTRSPPPGR 19 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 IISPGS(0.001)S(0.001)T(0.003)PS(0.042)S(0.139)T(0.407)RS(0.407)PPPGR 57.188 0.019463 14627000.0 22266.0 23267.0 16294.0 17927.0 15936.0 22763.0 22048.0 22066.0 17244.0 18378.0 True False 21948.48275691569 23213.12669102021 14954.3702166589 19245.41138271889 14998.675811381469 21789.479553144705 23189.537558307464 23091.26691589344 15301.799132629867 21554.612812854288 1.0182731161761587 1.0769447306971274 0.6937897862744593 0.8928674131061967 0.6958452903610902 1.0108963562616329 1.075850341625166 1.071291194900182 0.7099083275346287 1.0 14.395709027058107 IISPGSSTPSST(ph)RSPPPGRDESYPR ddPTM_PC-9_AZD4547_30min_R2 1 IISPGSSTPSSTRSPPPGRDESYPR 25 2 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 IISPGS(0.001)S(0.002)T(0.014)PS(0.074)S(0.199)T(0.471)RS(0.199)PPPGRDES(0.021)Y(0.019)PR 48.706 0.015021000000000001 29133000.0 15831.0 9115.8 21139.0 47679.0 24569.0 16521.0 16522.0 17663.0 17118.0 19846.0 True False 20864.928694744027 12062.304080815149 20858.68304802276 36687.34318320683 21158.018441810196 15487.939258311135 17992.42599264492 14933.58920536153 18022.822532910373 19151.19758065226 1.0894842793446549 0.6298459420105009 1.0891581563074422 1.9156683559189365 1.104788269908789 0.8087190993193043 0.9394935181924078 0.7797731260654099 0.9410807056326419 1.0 14.225146990480178 -6.650729923768245 6.053783895425907 0.8844205683937326 1.1789488197120896 0.17289382511166895 0.29967011964413803 0.42014582760252045 20.840203566906133 0.10977613516172112 0.10940911018238504 2.2349616541983847e-07 6.650729923768245 0.294528251318357 IISPGSSTPSST(ph)RSPPPGRDESYPR ddPTM_PC-9_Lapatinib_30min_R1 1 IISPGSSTPSSTRSPPPGRDESYPR 25 2 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 IIS(0.004)PGS(0.012)S(0.012)T(0.017)PS(0.049)S(0.152)T(0.372)RS(0.372)PPPGRDES(0.005)Y(0.005)PR 42.831 0.032302 29506000.0 33581.0 14896.0 17522.0 17070.0 17460.0 20500.0 11282.0 12331.0 25681.0 14142.0 True False 33102.128781998836 14861.50922720752 16081.40879687598 18325.384743850715 16433.037127680745 19623.262787834043 11866.12675675004 12903.943276528687 22788.535347081168 16586.425856969494 1.9957360957357528 0.8960043203619316 0.9695523879316466 1.1048422910322493 0.9907521529586016 1.1830917014341877 0.7154119193053264 0.7779821516584626 1.3739268208590938 1.0 14.017715418709317 -4.758067304351052 24.9978255194623 0.99301008155239 1.995737492395805 0.7311507270848241 0.18084448856968885 48.52489112817092 359666.77901689155 0.044396128532868236 0.31306505027197495 1.7455516168497303e-05 4.758067304351052 1.002727410843415 IISPGSSTPSSTRS(ph)PPPGR ddPTM_PC-9_AZD4547_30min_R2 1 IISPGSSTPSSTRSPPPGR 19 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 IISPGSSTPS(0.008)S(0.052)T(0.052)RS(0.888)PPPGR 75.877 0.010643999999999999 0.0 10877.0 11483.0 13683.0 12325.0 15053.0 16336.0 15123.0 14661.0 14725.0 13863.0 True False 14335.659744345336 15194.655187696113 13501.554479686629 9483.661669351794 12963.150783693642 15314.50733755648 16468.917702867042 12395.479326264249 15503.333438316697 13377.660589568803 1.0716118598137803 1.1358230451402025 1.0092612523160016 0.7089177966397694 0.9690147763056289 1.1447821713684327 1.2310760609152125 0.9265804916540933 1.158897202879058 1.0 13.707538227149456 -6.74824384146241 24.304106708109288 1.0963540165420191 0.9743270852565923 0.15830517980457937 0.13028818238974327 329.0347408426926 606028.3131087275 0.046382417597209354 0.046100851119572996 1.7854848048628247e-07 6.74824384146241 -0.12202693128542685 IISPGSSTPSSTRS(ph)PPPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IISPGSSTPSSTRSPPPGR 19 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 IISPGSS(0.001)T(0.001)PS(0.224)S(0.224)T(0.224)RS(0.325)PPPGR 63.93600000000001 0.0056061999999999996 5282700.0 15271.0 13300.0 15873.0 18493.0 15466.0 15951.0 17397.0 15977.0 12902.0 10522.0 True False 17856.078684001594 14620.336103362131 16251.47251868773 17456.897165114933 12435.548323609959 15114.501479869346 15749.03021662722 15557.620679030802 13090.667341814056 12429.555307893834 1.436582262332543 1.176255766292537 1.3074862387366868 1.4044667514394749 1.0004821584978443 1.2160130515908596 1.2670630466260715 1.2516634983031436 1.0531887117071967 1.0 13.601487061573588 -1.5228790301202444 0.028252356440580207 1.4894154374776157e-06 2.9396676967763056 0.4172123443702259 0.11255953681586628 1680.243273269797 3.657386381413361 124.68137453221232 286.695739948298 0.02999998032396275 1.5228790301202444 2.939666207360868 IISPGSSTPSSTRS(ph)PPPGR ddPTM_PC-9_Lapatinib_30min_R1 1 IISPGSSTPSSTRSPPPGR 19 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 IISPGSST(0.001)PS(0.088)S(0.278)T(0.278)RS(0.355)PPPGR 65.652 0.0049209 15643000.0 23511.0 20644.0 28397.0 25977.0 23618.0 25957.0 22432.0 23190.0 22362.0 21423.0 True False 23175.728828610652 20596.20008636358 26062.308275589938 27887.43523673168 22228.835674774567 24846.879618722352 23593.41919938104 24267.492059257176 19843.356077700602 25125.937005646836 0.9223826686902108 0.8197186867791145 1.03726711842558 1.1099062785385565 0.8846967844335051 0.9888936525287886 0.9390065410925221 0.9658343111265171 0.7897558635620626 1.0 14.61688977835618 -10.566950401789253 9.645224464091212 0.9999999984440995 0.9446385026016215 0.03588472638859719 0.09056209019129861 6.308001269353568e-11 0.0 0.08946462080928724 0.02169835772661901 2.7105011645635167e-11 10.566950401789253 -0.05536149584247796 IISPGSSTPSSTRS(ph)PPPGRDESYPR ddPTM_PC-9_AZD4547_30min_R2 1 IISPGSSTPSSTRSPPPGRDESYPR 25 2 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 IIS(0.016)PGS(0.045)S(0.045)T(0.045)PS(0.052)S(0.052)T(0.052)RS(0.664)PPPGRDES(0.015)Y(0.015)PR 57.227 0.014426 12167000.0 3558.7 1852.7 2982.6 14523.0 10966.0 6255.9 2904.4 5707.5 8260.0 5794.8 True False 4690.292574441638 2451.549043476846 2943.048775203781 11174.946728113282 9443.560186938439 5864.7175840487 3162.885973431664 4825.537020302379 8696.606736875785 5591.925815799845 0.838761587499844 0.4384087207577139 0.5263032579738937 1.9984075426284722 1.6887849549534257 1.0487831522153046 0.5656165831984054 0.862947252745726 1.5552078162953706 1.0 12.449129506268214 IISPGSSTPSSTRS(ph)PPPGRDESYPR ddPTM_PC-9_Lapatinib_30min_R1 1 IISPGSSTPSSTRSPPPGRDESYPR 25 2 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 IISPGS(0.001)S(0.002)T(0.015)PS(0.055)S(0.055)T(0.071)RS(0.78)PPPGRDES(0.012)Y(0.011)PR 55.843999999999994 0.0019091999999999998 14460000.0 39132.0 14269.0 22880.0 31093.0 27130.0 22353.0 18535.0 15642.0 28924.0 22180.0 True False 38573.970504070065 14235.961007184747 20998.8947193541 33379.682943207394 25534.266739632214 21397.014297388017 19494.651607548487 16368.78442392845 25666.274536777222 26013.783447007743 1.482828154645343 0.5472468484326624 0.8072218622919887 1.2831537177667602 0.9815668217446207 0.82252604051139 0.7493970128282464 0.6292350536888659 0.9866413545365892 1.0 14.666988619787066 -6.761112156742498 5.574520837127353 0.8077007109522872 0.9978645810083216 0.1043798530563892 0.2569701946245754 0.4002216140245061 40.194129888433196 0.0888713600749712 0.08333680342882825 1.7333562999145994e-07 6.761112156742498 0.1901638700560344 IISPVES(ph)DSSVR ddPTM_PC-9_Lapatinib_30min_R1 1 IISPVESDSSVR 12 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5 Q8NEV8-2 EXPH5 Exophilin-5 1 IIS(0.395)PVES(0.565)DS(0.039)S(0.001)VR 75.788 0.019363 5101500.0 8641.8 10717.0 9093.4 10002.0 7410.3 7159.3 8797.3 7157.3 9437.7 8726.5 True False 8518.566347287973 10692.185444950517 8345.77575353909 10737.580445693897 6974.440723210347 6853.113428143426 9252.781148480506 7489.854287008251 8374.726842613134 10234.863897669655 0.832308708006126 1.0446827189744057 0.8154261587630213 1.0491180491553682 0.6814395181941145 0.6695852037371782 0.9040453533131245 0.7317981325294998 0.8182548323402669 1.0 13.321204297205098 -6.263756627911 24.999662012570784 0.7860398931977722 0.9346225537722804 0.23372022100701684 0.1175097872640305 275.46286331971953 2971831.667878318 0.03403992338538733 0.04048437426962385 5.448078694425473e-07 6.263756627911 0.1485826605745082 IISSIEQK ddPTM_PC-9_Lapatinib_30min_R1 2 IISSIEQK 8 0 I3L3T1;B4DJF2;K7EIT4;P62258;P62258-2 I3L3T1;P62258 YWHAE 14-3-3 protein epsilon 0 ; 113.26 0.017125 16794000.0 115978.0 113900.0 137066.0 109917.0 115882.0 104867.0 116475.0 102870.0 130278.0 106758.0 False True 114324.13245223978 113636.27154799527 125796.96257006093 118000.66285236324 109066.0485927778 100382.0828669168 122505.50558344809 107649.71574539843 115604.7197518415 125210.97805390653 0.9130519881652894 0.9075583731889064 1.0046799771494648 0.9424146723106095 0.8710581954389182 0.8017035281339289 0.9783926895827484 0.8597466246054917 0.9232794244452808 1.0 16.934001532630667 -1.65975790375863 19.43628491787202 0.9158692344971459 0.03089537876368409 0.0 0.061565152236220576 0.0 0.0 0.014163510271937794 0.0 0.021889815255170846 1.65975790375863 -0.8849738557334618 IISVT(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 2 IISVTPVK 8 0 Q29RF7 Q29RF7 PDS5A Sister chromatid cohesion protein PDS5 homolog A 1 IIS(0.025)VT(0.975)PVK;IIS(0.055)VT(0.945)PVK 118.03 0.0086083 187242000.0 473050.0 547830.0 647820.0 649680.0 646020.0 611280.0 657380.0 766310.0 584650.0 701910.0 True False 623470.05994875 724905.3341004592 639229.483521931 499906.3134559417 556331.2741169056 573056.5649670379 715885.5464861972 647894.39755198 615553.4054133692 677336.3445447749 0.9204733585760447 1.0702294951965918 0.9437401206509083 0.7380473785028019 0.8213515760634482 0.8460443169518366 1.0569129388255853 0.9565327518153743 0.9087854363212581 1.0 19.36951288446825 -7.246172484156875 24.806112658480355 0.9769355190496376 0.8905921516804968 0.20105664079445162 0.08833171320722935 1464.452841216549 2379489.8091329336 0.03843102347781038 0.029652300085297147 5.6731924446119876e-08 7.246172484156875 -0.08634336736914083 IISVT(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IISVTPVK 8 0 Q29RF7 Q29RF7 PDS5A Sister chromatid cohesion protein PDS5 homolog A 1 IIS(0.078)VT(0.922)PVK;IIS(0.001)VT(0.999)PVK;IIS(0.014)VT(0.986)PVK;IIS(0.001)VT(0.999)PVK 119.22 0.0084814 182421000.0 700950.0 843210.0 866120.0 870340.0 947340.0 780150.0 935770.0 733390.0 671830.0 636460.0 True False 819606.9906064374 926918.3162192449 886771.5855783933 821577.6714803509 761715.5275370904 739237.5606244168 847127.091211889 714139.289590937 681654.2427725114 751845.1597854118 1.0901273752169476 1.2328579949677427 1.1794603902637235 1.0927485011871885 1.0131281921858695 0.9832311227958249 1.126730790491053 0.949848888825411 0.906641791731513 1.0 19.520076048293056 -6.061812673996536 2.327895069613648 0.9983705345336343 1.1743110921517734 0.6081693537263853 0.061923795600486095 0.21135815941728653 2.2693084879931598 0.020400738790642203 0.029987722964458813 8.673359066069702e-07 6.061812673996536 0.1759405576181391 IISVT(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 2 IISVTPVK 8 0 Q29RF7 Q29RF7 PDS5A Sister chromatid cohesion protein PDS5 homolog A 1 IIS(0.061)VT(0.939)PVK;IIS(0.001)VT(0.999)PVK 134.84 0.0086433 156014000.0 245100.0 322340.0 352930.0 312261.0 318640.0 296111.0 302954.0 294333.0 324266.0 254823.0 True False 241604.82905416487 321593.6415345113 323913.4577491972 335225.7156121602 299898.2216703433 283447.0227984547 318639.4757546933 308008.7856954437 287743.74840764096 298868.8160196954 0.8083975848395074 1.076036121190102 1.0837981093613036 1.121648354206579 1.0034443394408201 0.9483994569034447 1.066151631335452 1.0305818780208436 0.9627760843027486 1.0 18.189152848466087 -4.755145830342194 24.981562252036973 1.0353916195055028 0.8083972052771861 0.6212693859891893 0.05245813744398823 147.32599294735493 584738.6712722618 0.013932864712803396 0.12702511957384624 1.75733342555714e-05 4.755145830342194 -0.2269944142283168 IISVT(ph)PVKNIDPVK ddPTM_PC-9_AZD4547_30min_R2 2 IISVTPVKNIDPVK 14 1 Q29RF7 Q29RF7 PDS5A Sister chromatid cohesion protein PDS5 homolog A 1 IIS(0.009)VT(0.991)PVKNIDPVK;IIS(0.061)VT(0.939)PVKNIDPVK 73.082 0.015355 78948000.0 183871.0 114119.0 250500.0 336120.0 330830.0 229210.0 196398.0 237550.0 216270.0 270610.0 True False 242338.15324561222 151005.73503132418 247178.20632620784 258632.72700223344 284899.9650414784 214877.4624658006 213877.04152665962 200842.10585594893 227701.59067604423 261136.02626727396 0.928015014663576 0.5782646584227681 0.9465496195964159 0.9904138111434752 1.0910021459462738 0.8228564458810923 0.8190254120959758 0.7691091448653128 0.8719654424203828 1.0 17.994441979700547 -5.30929013965653 24.99658025841389 0.9080419177160736 0.7531389040686176 0.2181692725912746 0.12130364701023283 554.4057860412912 289612.8912989079 0.03306858185112415 0.06883799916978217 4.9058002424153455e-06 5.30929013965653 -0.15490301364745596 IISVT(ph)PVKNIDPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IISVTPVKNIDPVK 14 1 Q29RF7 Q29RF7 PDS5A Sister chromatid cohesion protein PDS5 homolog A 1 IIS(0.007)VT(0.993)PVKNIDPVK;IIS(0.001)VT(0.999)PVKNIDPVK 123.95 0.00040839 9525900.0 46538.0 25932.0 32514.8 53886.0 54491.0 72534.0 55921.0 66640.0 69506.0 52603.0 True False 54415.96423260209 28506.357581382483 33290.07614506568 50866.94212076914 43813.879716916475 68730.18935119067 50623.75804702022 64890.77061091638 70522.3937575667 62139.50749488109 0.8757063972076824 0.45874772315713597 0.5357312519383589 0.8185926179887963 0.705088943946422 1.1060626664421584 0.8146791001069729 1.0442755861279063 1.1349042919816539 1.0 15.923223186546563 -6.511367652759536 1.2813066521114242 1.0228421286449356 0.6193924570134122 0.5673196365538182 0.14452033057222324 0.3138052347712636 1.0703002237520216 0.06210411362871688 0.07047013422652045 3.0805789765243143e-07 6.511367652759536 -0.40344967163152345 IISVT(ph)PVKNIDPVK ddPTM_PC-9_Lapatinib_30min_R1 1 IISVTPVKNIDPVK 14 1 Q29RF7 Q29RF7 PDS5A Sister chromatid cohesion protein PDS5 homolog A 1 IIS(0.026)VT(0.974)PVKNIDPVK 79.875 0.008837000000000001 27542000.0 119070.0 77671.0 98940.0 88135.0 75021.0 69160.0 49259.0 48735.0 84931.0 49839.0 True False 117372.03996523611 77491.15757159199 90805.53511944452 94616.74190974106 70608.41227696091 66202.18801983423 51809.38999386192 50999.406015864544 75365.17641692114 58453.60474370689 2.0079521268168214 1.3256865493814507 1.5534633923363064 1.6186639356904244 1.2079394005989443 1.1325595454737383 0.886333532739736 0.8724766631497629 1.2893161464953955 1.0 15.835004375829246 -6.448799116834308 1.8211241254492743 1.0076967008884568 1.6142524859801832 0.6779167540372669 0.19220991197537088 0.20992540623134714 1.3907609215549015 0.0700780559306169 0.08052225129733513 3.557958540927035e-07 6.448799116834308 0.6065557850917265 IITEGFEAAK ddPTM_PC-9_Lapatinib_30min_R1 1 IITEGFEAAK 10 0 P40227-2;P40227 P40227-2 CCT6A T-complex protein 1 subunit zeta 0 110.76 0.0078035 6961600.0 46050.0 39485.0 40399.0 37066.0 39817.0 35661.0 29843.0 25375.0 37550.0 37958.0 False True 45393.318555464255 39393.574908451155 37077.55016464975 39791.95728855129 37475.042343233916 34135.862159851225 31388.124517079523 26554.015135991845 33320.72358097031 44518.98972414423 1.0196394580545893 0.8848712684754978 0.8328479687970385 0.893819862829697 0.8417765671557876 0.7667708178323314 0.7050502428642631 0.5964649085823854 0.7484609104437808 1.0 15.44213323331412 -6.629605162412329 1.7701006324147532 0.7290640221120769 0.9043388799191137 0.27432497802491496 0.10532889669495211 0.3979061640337544 2.5593179413199767 0.040938944816946016 0.04125654407334014 2.3463610333542435e-07 6.629605162412329 0.17527485780703678 IIVEKPFGR ddPTM_PC-9_AZD4547_30min_R2 2 IIVEKPFGR 9 1 P11413;P11413-2;P11413-3;E7EUI8;E7EM57;E9PD92 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ; 136.27 0.0013109000000000003 23162000.0 91174.0 80366.0 102516.0 133878.0 111245.0 87714.0 90082.0 113559.0 86884.0 91554.0 False True 120165.43546298999 106342.73785721386 101156.57085723564 103014.49549448118 95800.5519784758 82229.22971390974 98099.12348804275 96011.06587621884 91476.5108627986 88348.72232686871 1.3601264658747096 1.203670353757598 1.1449692558425577 1.1659987012981659 1.0843456414008699 0.9307347921759599 1.1103626731023901 1.086728402488961 1.0354027591294173 1.0 16.430921650647576 -1.5228787453740276 0.4374374332981019 1.0340405905798427 7.7947725103119465 0.7781166764628981 0.05301019815929563 40.74916295842646 0.504406295525591 0.03612009791267996 244.04149934966102 0.029999999993528124 1.5228787453740276 6.760731919732104 IIVEKPFGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IIVEKPFGR 9 1 P11413;P11413-2;P11413-3;E7EUI8;E7EM57;E9PD92 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ; 112.41 0.0028127 23763000.0 100951.0 107760.0 122289.0 116269.0 138256.0 104087.0 111583.0 96820.0 107646.0 93349.0 False True 118040.01042686413 118457.70063897021 125204.83354361498 109754.82487918389 111165.72927900036 98628.49448530869 101013.05044903827 94278.57758926954 109220.11910377609 110272.43474972264 1.0704398673591546 1.0742276699324276 1.1354137035949494 0.9953060810554012 1.0081007962806403 0.894407516340404 0.9160317415526399 0.8549605148670817 0.9904571287617353 1.0 16.750712674069845 -6.241752970298592 1.6257516272943826 0.9230765941375847 1.0891766781880796 0.6425033723353337 0.04925274502650629 0.21379450023263277 1.1210910150112634 0.01714420582766964 0.02350189703106513 5.731219340042802e-07 6.241752970298592 0.16610008405049492 IIVEKPFGR ddPTM_PC-9_Lapatinib_30min_R1 2 IIVEKPFGR 9 1 P11413;P11413-2;P11413-3;E7EUI8;E7EM57;E9PD92 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ; 148.99 0.00038333 45848000.0 191662.0 214755.0 217710.0 167001.0 189846.0 189317.0 159416.0 162141.0 188468.0 160409.0 False True 188928.86473349403 214257.74799200767 199810.72418490247 179282.8106390046 178679.63153159653 181220.3532294819 167669.78045152148 169674.66278482167 167240.74918397635 188135.4819184425 1.004217082322597 1.138848163074785 1.0620576307425158 0.9529452329291316 0.94973914388491 0.9632438888271042 0.891218279198429 0.9018748672745119 0.8889378413821796 1.0 17.521412437919693 -5.788832712820898 3.359677541858123 0.928681282494978 1.0789320705991647 0.6555046905944616 0.04428908149265228 0.13184239777382145 3.081378979737086 0.012685186140635398 0.02129798600025086 1.6261750263049823e-06 5.788832712820898 0.15025078810418668 IIYCSPGLVPTANLNHS(ph)VGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IIYCSPGLVPTANLNHSVGK 20 0 A0A499FJD3;A0A3B3ISA1;Q96S15 A0A499FJD3 WDR24 WD repeat-containing protein 24 1 IIYCSPGLVPT(0.008)ANLNHS(0.992)VGK 123.55 4.0368000000000004e-05 0.0 7281.1 9381.1 12020.0 12945.0 11481.0 9094.9 10164.0 9245.1 9298.5 6857.6 True False 8513.646421719866 10312.393610469959 12306.60238610385 12219.733618256249 9231.380467048106 8617.947433343594 9201.192339012421 9002.425920993153 9434.472971466283 8100.828595268265 1.0509599507750023 1.2730047907066544 1.5191782224959307 1.5084547802176504 1.1395600287654772 1.0638353017834965 1.1358334805882553 1.1112969266195207 1.1646306128458273 1.0 12.983853766627982 -6.4153203101592915 7.333502468998986 1.1043375381919824 1.3456005781006355 0.44641387944215694 0.12884497723031724 0.2711515310410361 16.383912967663278 0.043121679978042844 0.04885076067798268 3.8430823426176333e-07 6.4153203101592915 0.24126303990865305 IIYGGS(ph)VTGATCK ddPTM_PC-9_AZD4547_30min_R2 2 IIYGGSVTGATCK 13 0 P60174;P60174-3;P60174-4 P60174 TPI1 Triosephosphate isomerase 1 IIYGGS(0.976)VT(0.024)GATCK;IIY(0.041)GGS(0.669)VT(0.274)GAT(0.016)CK 198.48 6.8071e-07 68366000.0 88215.0 72786.0 109859.0 131514.0 121434.0 112560.0 85737.0 106289.0 88182.0 94565.0 True False 116265.53501401327 96312.6510921928 108402.19787940451 101195.47917104526 104574.98520341811 105521.60540618021 93367.42690542286 89864.47732823806 92843.12049287898 91254.30813334582 1.2740826969409451 1.0554312783946096 1.18791320757154 1.1089391968560305 1.1459731309409236 1.1563465612164439 1.0231563727269646 0.9847696965377584 1.0174108202892898 1.0 16.477605049946156 -7.31149489987013 4.406230549589924 1.0019191528790174 1.149645646072974 0.6522261758478785 0.05313432133615711 0.1340285834699192 5.676753389414169 0.02129621955537757 0.014329391560000236 4.880958331590439e-08 7.31149489987013 0.1477264931939566 IIYGGS(ph)VTGATCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IIYGGSVTGATCK 13 0 P60174;P60174-3;P60174-4 P60174 TPI1 Triosephosphate isomerase 1 IIYGGS(0.875)VT(0.123)GAT(0.002)CK;IIYGGS(0.922)VT(0.078)GATCK;IIYGGS(0.998)VT(0.002)GATCK;IIYGGS(0.569)VT(0.431)GATCK 183.81 5.545e-05 62895900.0 152052.0 162867.0 164784.0 166252.0 177291.0 171175.0 166995.0 149237.0 157711.0 137414.0 True False 177791.40043610882 179035.35940949508 168713.07550680017 156937.43943625636 142552.10124409213 162198.28166363435 151176.0246608992 145319.68687967185 160017.22501510158 162326.07043137433 1.0952732359234476 1.1029365704086629 1.0393467608650457 0.96680366264767 0.878183651370764 0.9992127649773053 0.9313108132239979 0.8952331963281759 0.9857764965902451 1.0 17.308535197437777 -5.630786985188403 2.4378317342421187 0.9431949370642814 1.0981184386370995 0.7088815168454414 0.03888442482956739 0.142974811200951 1.710695508332403 0.010955446188264847 0.02274359009419834 2.3399846839895357e-06 5.630786985188403 0.1549235015728181 IIYGGS(ph)VTGATCK ddPTM_PC-9_Lapatinib_30min_R1 1 IIYGGSVTGATCK 13 0 P60174;P60174-3;P60174-4 P60174 TPI1 Triosephosphate isomerase 1 IIYGGS(0.573)VT(0.173)GAT(0.254)CK 162.41 0.00032711 28697000.0 53129.0 54167.0 58435.0 46552.0 53648.0 50645.0 49526.0 54736.0 51796.0 38714.0 True False 52371.37071733467 54041.57963951053 53630.699865623086 49975.5893729196 50492.53011602612 48479.0314092612 52090.213947420874 57279.2343835921 45962.18904393972 45405.66331683755 1.1534105415857687 1.1901946958116691 1.181145609334937 1.1006466093049545 1.1120315490975823 1.0676868889895497 1.1472184336112214 1.2614997821725806 1.0122567469881185 1.0 15.470584631461184 -14.522878745258039 0.18301782266053987 0.41546766759602216 1.1671915099468155 0.3334381933373004 0.06306147232470134 170.4123640010863 1.6443164981437195 36.14620380375455 0.19278565864295186 3.0000000001540344e-15 14.522878745258039 0.7517238423507934 IIYGGSVT(ph)GATCK ddPTM_PC-9_Lapatinib_30min_R1 1 IIYGGSVTGATCK 13 0 P60174;P60174-3;P60174-4 P60174 TPI1 Triosephosphate isomerase 1 IIYGGS(0.246)VT(0.754)GATCK 159.52 0.00065747 24169000.0 42664.0 48000.0 55704.0 45165.0 38405.0 36256.0 36911.0 50948.0 44887.0 27112.0 True False 42055.60353638064 47888.85894911121 51124.232143658206 48486.584766023276 36146.0934071351 34705.41539686394 38822.07097308992 53315.2300748182 39831.35337893511 31798.27307553082 1.3225750793599846 1.5060207463267024 1.6077675671953067 1.524818176473059 1.1367313351035402 1.0914245347358251 1.2208861431208982 1.6766706150418262 1.2526263072313149 1.0 14.956660796221987 -6.246908098190462 24.453509537914496 1.256199905270711 1.499809525176653 0.32507239389477127 0.18134181115092268 845.2633576205031 1422423.6139669556 0.05710231423743425 0.0733654075153486 5.663591245964303e-07 6.246908098190462 0.2436096199059421 IIYGGSVTGATCK ddPTM_PC-9_Lapatinib_30min_R1 2 IIYGGSVTGATCK 13 0 P60174;P60174-3;P60174-4 P60174 TPI1 Triosephosphate isomerase 0 ; 121.29 0.00091933 35949000.0 106053.0 100362.0 102510.0 101166.0 104457.0 107893.0 100016.0 95817.0 86286.0 91531.0 False True 104540.66477226179 100129.61795522283 94082.02350004329 108606.08511988274 98313.04463036357 103278.66790086732 105194.3390979535 100269.00761715611 76567.56204813863 107352.01139260885 0.9738118868582222 0.932722327754324 0.8763880832746167 1.0116818838418171 0.9158006762519998 0.9620561977470132 0.9799009607117254 0.9340207632482198 0.7132382621888189 1.0 16.711989696830116 -8.031117201782985 24.85322891430142 0.8456225584616163 0.9489163385070967 0.20009106522354259 0.07325929426145351 828.5914500462178 661788.7650810515 0.04503959198488758 0.0170666176165666 9.308566340082512e-09 8.031117201782985 0.1032937800454804 IKDNGDLVLS(ph)SPSNVTLPQVK ddPTM_PC-9_AZD4547_30min_R2 1 IKDNGDLVLSSPSNVTLPQVK 21 1 A0A494C0P1;P04150-7;P04150-5;P04150-2;P04150-6;P04150-10;P04150;P04150-3;P04150-9;P04150-8;P04150-13;P04150-12;P04150-11 A0A494C0P1 NR3C1 Glucocorticoid receptor 1 IKDNGDLVLS(0.914)S(0.083)PS(0.002)NVTLPQVK 110.36 1.7129e-05 16515000.0 66836.0 59578.0 68806.0 88036.0 87786.0 72285.0 74419.0 91240.0 80216.0 81805.0 True False 88088.45772483823 78835.42338871019 67893.58748295832 67740.66034264141 75598.42919666025 67765.0075229721 81042.1468312941 77140.95448662098 84456.05399579032 78941.03184950413 1.11587669505984 0.9986621854526139 0.8600544722089897 0.8581172396097445 0.9576569678083721 0.8584256619822453 1.0266162594098796 0.9771971898427312 1.0698625545812503 1.0 16.268487756576683 -7.3077251916547965 24.896940925801392 1.0165188077938647 0.9373122365646074 0.19205466565785057 0.07700212549621924 743.2545860886332 399790.6706345866 0.03419494124890695 0.02305430449404024 4.923509818676308e-08 7.3077251916547965 -0.07920657122925734 IKDNGDLVLSS(ph)PSNVTLPQVK ddPTM_PC-9_AZD4547_30min_R2 1 IKDNGDLVLSSPSNVTLPQVK 21 1 A0A494C0P1;P04150-7;P04150-5;P04150-2;P04150-6;P04150-10;P04150;P04150-3;P04150-9;P04150-8;P04150-13;P04150-12;P04150-11 A0A494C0P1 NR3C1 Glucocorticoid receptor 1 IKDNGDLVLS(0.122)S(0.598)PS(0.277)NVT(0.003)LPQVK 87.06200000000001 0.00021085 18037000.0 108540.0 101750.0 113280.0 161590.0 148240.0 128690.0 123370.0 171560.0 132130.0 135070.0 True False 143053.4622277503 134638.69767030227 111777.83318416278 124337.92204061324 127659.43480865931 120642.99395630191 134349.6910006419 145049.3440566055 139114.12205125878 130341.24041210863 1.0975303117835045 1.032970817560168 0.8575784059653515 0.9539415280036134 0.9794247346812868 0.9255934159814413 1.0307535096018687 1.1128430541093002 1.067307028929695 1.0 16.991934104194435 -7.4940058421831095 7.1471565780395885 1.0685729462175926 0.9715282236405381 0.26481095020558343 0.06464263857868434 0.25386930828067106 49.06266321768651 0.02944111600530442 0.019055655629750094 3.206226193663875e-08 7.4940058421831095 -0.09704472257705443 IKDNGDLVLSS(ph)PSNVTLPQVK ddPTM_PC-9_Lapatinib_30min_R1 1 IKDNGDLVLSSPSNVTLPQVK 21 1 A0A494C0P1;P04150-7;P04150-5;P04150-2;P04150-6;P04150-10;P04150;P04150-3;P04150-9;P04150-8;P04150-13;P04150-12;P04150-11 A0A494C0P1 NR3C1 Glucocorticoid receptor 1 IKDNGDLVLS(0.313)S(0.681)PS(0.006)NVTLPQVK 115.79 1.5658000000000001e-06 13707000.0 121390.0 93075.0 110820.0 84433.0 95120.0 99009.0 92824.0 83313.0 94613.0 86475.0 True False 119658.95633980042 92859.49055601099 101708.8073775708 90642.48448023113 89525.22861311516 94774.61587125178 97629.9725286798 87184.02612905978 83956.68762094113 101422.08852930527 1.179811597995497 0.9155746238570095 1.0028269862356727 0.8937154203252338 0.8826995175439265 0.9344573479559855 0.9626105510583155 0.8596157641130464 0.8277948998918748 1.0 16.630012362885644 IKDNGDLVLSSPS(ph)NVTLPQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IKDNGDLVLSSPSNVTLPQVK 21 1 A0A494C0P1;P04150-7;P04150-5;P04150-2;P04150-6;P04150-10;P04150;P04150-3;P04150-9;P04150-8;P04150-13;P04150-12;P04150-11 A0A494C0P1 NR3C1 Glucocorticoid receptor 1 IKDNGDLVLS(0.076)S(0.305)PS(0.605)NVT(0.014)LPQVK 79.467 0.00046371 15072000.0 34459.0 34375.0 34848.0 31477.0 39161.0 43181.0 42593.0 42681.0 36660.0 29679.0 True False 40292.22810372677 37787.52282353934 35678.90848177595 29713.4457398109 31487.68316959069 40916.51234419394 38558.28269338409 41560.66897425757 37196.08314609387 35059.56776116528 1.1492505662992683 1.0778091470196547 1.0176653838070617 0.8475131793474031 0.898119548537872 1.1670569535519566 1.099793441723325 1.1854301586767826 1.0609395814427343 1.0 15.097520589204592 -6.774983947417248 24.994347103938466 1.114055249408372 0.9952256066761584 0.23606468083551935 0.09286156022514061 341.9073645701565 630931.8339762344 0.03535595216535307 0.031349372363911956 1.6788660719583945e-07 6.774983947417248 -0.11882964273221353 IKDNGDLVLSSPS(ph)NVTLPQVK ddPTM_PC-9_Lapatinib_30min_R1 1 IKDNGDLVLSSPSNVTLPQVK 21 1 A0A494C0P1;P04150-7;P04150-5;P04150-2;P04150-6;P04150-10;P04150;P04150-3;P04150-9;P04150-8;P04150-13;P04150-12;P04150-11 A0A494C0P1 NR3C1 Glucocorticoid receptor 1 IKDNGDLVLS(0.274)S(0.274)PS(0.358)NVT(0.094)LPQVK 79.568 0.00045821 13015000.0 153630.0 115790.0 137060.0 104290.0 119100.0 113540.0 113110.0 98496.0 124070.0 99888.0 True False 151439.20802770872 115521.89536911612 125791.45586689972 111959.83450124138 112094.7721596092 108684.15887466725 118966.2823485196 103072.48373732629 110095.93008497973 117153.50770760606 1.2926561994684236 0.9860728682357327 1.0737318781854353 0.955667795971358 0.9568195980898622 0.9277072535115486 1.0154734986291483 0.8798070647152669 0.9397578633305563 1.0 16.83804062519448 -1.7017193984227177 0.9883219345194268 0.9544223391719825 199.999999999385 0.7799172295989435 0.05108397643802892 461.3807093111082 0.9980527942186499 0.01583454726210998 207429.60664087508 0.0198737856581981 1.7017193984227177 199.04557766021304 IKDNGDLVLSSPSNVT(ph)LPQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IKDNGDLVLSSPSNVTLPQVK 21 1 A0A494C0P1;P04150-7;P04150-5;P04150-2;P04150-6;P04150-10;P04150;P04150-3;P04150-9;P04150-8;P04150-13;P04150-12;P04150-11 A0A494C0P1 NR3C1 Glucocorticoid receptor 1 IKDNGDLVLS(0.04)S(0.04)PS(0.08)NVT(0.841)LPQVK 74.953 0.0010817000000000001 12630000.0 76159.0 69502.0 68491.0 78874.0 89405.0 90782.0 90506.0 84505.0 78370.0 65372.0 True False 89051.21449118448 76401.69923728368 70124.08519356391 74454.94549295813 71886.73204916265 86021.23210742255 81932.61647330383 82286.83329044863 79516.01298852656 77223.42611553273 1.1531632170522503 0.9893590984033825 0.9080675220062419 0.96414973069917 0.9308928088947266 1.113926646801808 1.0609813704810993 1.0655682793371615 1.0296877125027313 1.0 16.236750942249827 -6.76005207033397 24.999987978294282 1.058565101098483 0.9832485312349791 0.18544989470381223 0.06711928587891317 59.75034944431114 1076736.5407948997 0.023519578963960258 0.02231041348511034 1.7375924852199751e-07 6.76005207033397 -0.07531656986350377 IKDPDASKPEDWDER ddPTM_PC-9_AZD4547_30min_R2 1 IKDPDASKPEDWDER 15 2 P27797;K7EJB9 P27797 CALR Calreticulin 0 73.722 0.03565 8563900.0 31771.0 32142.0 36632.0 50533.0 42186.0 40499.0 28932.0 42519.0 35170.0 38863.0 False True 41873.51712214724 42531.27292893224 36146.23574507638 38883.39757706729 36329.20208336542 37966.591127797474 31506.89195128938 35948.66553941952 37029.014399021966 37502.41819897659 1.1165551218585135 1.1340941456967935 0.9638374665147 1.0368237421588025 0.9687162542589536 1.0123771466244689 0.8401296093527424 0.9585692674186148 0.9873767126844224 1.0 15.194696004789716 -5.107343836044919 0.7910405651769269 0.9524616691256472 1.199819655059228 0.5461245625941757 0.05337246969349594 1.2951146574243217 0.8516083124954485 0.02176757982989553 0.2595251342764615 7.810092255706156e-06 5.107343836044919 0.24735798593358072 IKEEVLS(ph)ESEAENQQAGAAALAPEIVIK ddPTM_PC-9_AZD4547_30min_R2 3 IKEEVLSESEAENQQAGAAALAPEIVIK 28 1 Q9UJX5;Q9UJX5-3 Q9UJX5 ANAPC4 Anaphase-promoting complex subunit 4 1 IKEEVLS(0.724)ES(0.276)EAENQQAGAAALAPEIVIK;IKEEVLS(0.5)ES(0.5)EAENQQAGAAALAPEIVIK;IKEEVLS(0.84)ES(0.16)EAENQQAGAAALAPEIVIK 82.581 2.3512e-06 36982000.0 124804.0 111168.0 150141.0 176561.0 154664.0 151764.0 125283.0 166226.0 121809.0 143757.0 True False 164489.0759155348 147100.8819912742 148150.0322396135 135857.58929025746 133191.57329497047 142274.17308869533 136432.94429467004 140539.59119347946 128247.57506199784 138724.11118622543 1.1857280937610195 1.060384389803757 1.067947244158116 0.979336527216095 0.9601184116881599 1.0255908066169135 0.9834840038118559 1.0130869824411193 0.9244793422380359 1.0 17.081859034021043 -1.5228892816348227 0.628176046931484 0.9818417058743193 16.560643138631143 0.7933726367890774 0.03135219003710646 83.43951467287681 0.5843252319946617 0.013273914878839816 1798.163021845441 0.029999272183245603 1.5228892816348227 15.578801432756823 IKEEVLS(ph)ESEAENQQAGAAALAPEIVIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IKEEVLSESEAENQQAGAAALAPEIVIK 28 1 Q9UJX5;Q9UJX5-3 Q9UJX5 ANAPC4 Anaphase-promoting complex subunit 4 1 IKEEVLS(0.931)ES(0.069)EAENQQAGAAALAPEIVIK;IKEEVLS(0.5)ES(0.5)EAENQQAGAAALAPEIVIK 70.666 6.488199999999999e-05 10622300.0 33370.1 31950.7 32363.8 40309.8 37561.5 37808.8 39692.8 34012.6 36393.5 26979.8 True False 39018.99884048207 35122.55434117991 33135.47573239498 38051.37259213488 30201.593712483875 35826.03996941157 35932.8106330138 33119.80528932858 36925.68608776233 31871.024168020725 1.2242781604625557 1.1020215150921242 1.0396740173051295 1.1939174716046776 0.9476191776349644 1.1240944056438353 1.1274444913843924 1.039182334233265 1.1585974110243196 1.0 14.959957760082967 -1.5228787452803376 0.011354565614854109 7.835574558748238e-13 2.353051232996963 0.1593040424360641 0.07638816742980907 20380.65352035791 17.94956904128719 1571.0141742583983 2197.27707786226 0.029999999999999995 1.5228787452803376 2.3530512329961795 IKEEVLS(ph)ESEAENQQAGAAALAPEIVIK ddPTM_PC-9_Lapatinib_30min_R1 3 IKEEVLSESEAENQQAGAAALAPEIVIK 28 1 Q9UJX5;Q9UJX5-3 Q9UJX5 ANAPC4 Anaphase-promoting complex subunit 4 1 IKEEVLS(0.725)ES(0.275)EAENQQAGAAALAPEIVIK;IKEEVLS(0.5)ES(0.5)EAENQQAGAAALAPEIVIK;IKEEVLS(0.5)ES(0.5)EAENQQAGAAALAPEIVIK 72.697 3.5007e-05 10752500.0 103774.5 81850.3 96596.4 85505.5 86739.8 87858.6 77991.9 89349.2 85979.3 74276.9 True False 102294.6566000873 81660.78065921724 88654.61686488701 91793.85970798615 81637.9355010081 84101.09248639978 82029.93896470242 93500.69001729092 76295.40583183272 87115.56319725199 1.1742408915897833 0.9373845230652562 1.0176668050018824 1.0537021898158576 0.9371222833761502 0.9653968751366885 0.941622093161076 1.0732949037542392 0.8757953577029668 1.0 16.41064285889904 -4.753439793924524 24.99920603885897 0.9810862561051314 1.1742412434072684 0.5177482726883129 0.0567483998546561 236.32007835269468 738456.9803281868 0.013414824571420127 0.14448079397083802 1.764250324862196e-05 4.753439793924524 0.19315498730213698 IKEEVLSES(ph)EAENQQAGAAALAPEIVIK ddPTM_PC-9_AZD4547_30min_R2 1 IKEEVLSESEAENQQAGAAALAPEIVIK 28 1 Q9UJX5;Q9UJX5-3 Q9UJX5 ANAPC4 Anaphase-promoting complex subunit 4 1 IKEEVLS(0.471)ES(0.529)EAENQQAGAAALAPEIVIK 54.326 0.0016760000000000002 1199300.0 3349.1 3590.8 3182.5 6292.8 5484.1 4329.8 2244.1 4586.8 4201.4 4354.3 True False 4414.044134392473 4751.455878078832 3140.2979705914413 4842.09218279083 4722.727377456604 4059.056921532323 2443.8205526022557 3878.015454178354 4423.477426671905 4201.857282345773 1.050498348180032 1.1307989678855144 0.7473595030905729 1.1523695017284434 1.123961872122426 0.9660149426270546 0.5816048448075664 0.9229288844416373 1.0527433773767796 1.0 12.036811445828528 -7.00582032730399 24.832867237872065 0.8673128634631159 1.0367734866045828 0.16404417848360597 0.1582613141289097 407.3284386317336 1737902.7474709917 0.05802423653349282 0.04958086748506882 9.866876053818594e-08 7.00582032730399 0.16946062314146693 IKEEVLSES(ph)EAENQQAGAAALAPEIVIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IKEEVLSESEAENQQAGAAALAPEIVIK 28 1 Q9UJX5;Q9UJX5-3 Q9UJX5 ANAPC4 Anaphase-promoting complex subunit 4 1 IKEEVLS(0.451)ES(0.549)EAENQQAGAAALAPEIVIK;IKEEVLS(0.449)ES(0.551)EAENQQAGAAALAPEIVIK;IKEEVLS(0.462)ES(0.538)EAENQQAGAAALAPEIVIK 67.87100000000001 0.00076571 11082500.0 60194.0 60339.0 63726.0 79448.0 81934.0 73524.0 73329.0 70799.0 63156.0 61855.0 True False 70383.65531430773 66329.05715344107 65245.46952220082 74996.78613389118 65879.62086814028 69668.27200839523 66382.74626401425 68940.60126774127 64079.537020586606 73068.82185608947 0.9632515418536481 0.9077614154512781 0.8929317301803921 1.0263855941402595 0.9016105528277372 0.9534610007207767 0.9084961899995653 0.9435022971017814 0.8769750954352672 1.0 16.156968325416067 IKGEHPGLSIGDVAK ddPTM_PC-9_AZD4547_30min_R2 2 IKGEHPGLSIGDVAK 15 1 Q5T7C4;P09429;B2RPK0 Q5T7C4 HMGB1;HMGB1P1 High mobility group protein B1;Putative high mobility group protein B1-like 1 0 ; 84.759 0.0027055 14724200.0 143610.0 141599.0 193990.0 254260.0 224200.0 220050.0 157260.0 226340.0 170536.0 198584.0 False True 189274.99272643484 187368.10763063515 191417.56584918583 195644.28527784083 193073.69997370016 206290.23871384078 171255.83534701262 191364.35377577602 179550.1848038558 191631.63460426504 0.9877022294221053 0.9777514449405266 0.9988829153624803 1.020939395950268 1.007525194743619 1.0764936548177286 0.8936720479406748 0.9986052364003418 0.9369548257240595 1.0 17.547976215674943 -10.063351539532874 5.0671730907717345 0.9999999947061973 0.9902779628735104 0.004363528613978485 0.0459931870396749 42199255.164267965 48142384.341279685 0.2559890456063435 0.011408317809576131 8.642680540545682e-11 10.063351539532874 -0.009722031832686828 IKGEHPGLSIGDVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IKGEHPGLSIGDVAK 15 1 Q5T7C4;P09429;B2RPK0 Q5T7C4 HMGB1;HMGB1P1 High mobility group protein B1;Putative high mobility group protein B1-like 1 0 65.038 0.015645 6291000.0 88017.0 74037.0 89732.0 124020.0 114540.0 119290.0 103110.0 100570.0 111770.0 97700.0 False True 102916.53968500873 81386.90406651291 91871.55119050496 117071.56147826479 92096.70923226986 113034.2224019567 93342.67434824575 97930.14406272289 113404.42480193415 115412.23660722552 0.891729878134651 0.7051843587737696 0.7960295536353312 1.0143773738367652 0.7979804563158777 0.9793954759462659 0.8087762363180987 0.8485247920114551 0.982603128885506 1.0 16.816436668581908 -1.5229226695078886 0.03877417904181062 1.372550425088707 0.07536794988279139 0.24482355675264766 0.08834169783428897 1185.2030289763625 3.5158620788315704 32.87109870685986 102.75002502518464 0.029996965975284704 1.5229226695078886 -1.2971824752059158 IKGEHPGLSIGDVAK ddPTM_PC-9_Lapatinib_30min_R1 2 IKGEHPGLSIGDVAK 15 1 Q5T7C4;P09429;B2RPK0 Q5T7C4 HMGB1;HMGB1P1 High mobility group protein B1;Putative high mobility group protein B1-like 1 0 ; 72.315 0.0089616 22675400.0 218182.0 211859.0 235121.0 226978.0 241096.0 209754.0 200504.0 217277.0 206688.0 192292.0 False True 215070.68467032138 211368.45350207778 215790.25897330666 243670.7192964119 226915.20729297324 200783.31038045557 210885.11604639326 227372.48262868528 183408.6209188707 225529.41598701605 0.9536258661828096 0.9372101310023633 0.956816466840538 1.0804387455623095 1.0061446144392843 0.8902754858018825 0.9350670072170724 1.008172178487685 0.813235914774992 1.0 17.782956092089705 -6.74779804583726 24.96309350729394 0.9302181786043972 0.9876207156759648 0.171640556619039 0.06313019575534405 441.5208584175087 807963.6842228852 0.02113812404472247 0.021026638078710552 1.7873185144951258e-07 6.74779804583726 0.057402537071567616 IKGS(ph)SPGIQDTLEAEDGAFETDEAPEDR ddPTM_PC-9_AZD4547_30min_R2 6 IKGSSPGIQDTLEAEDGAFETDEAPEDR 28 1 Q9UNX4 Q9UNX4 WDR3 WD repeat-containing protein 3 1 IKGS(0.594)S(0.406)PGIQDTLEAEDGAFETDEAPEDR;IKGS(0.5)S(0.5)PGIQDTLEAEDGAFETDEAPEDR;IKGS(0.498)S(0.498)PGIQDT(0.004)LEAEDGAFETDEAPEDR;IKGS(0.5)S(0.5)PGIQDTLEAEDGAFETDEAPEDR;IKGS(0.5)S(0.5)PGIQDTLEAEDGAFETDEAPEDR;IKGS(0.498)S(0.498)PGIQDT(0.004)LEAEDGAFETDEAPEDR 137.41 1.2385999999999998e-11 41875500.0 119557.0 108388.0 138961.0 186058.0 162212.0 150978.0 122990.0 158651.0 133083.0 148598.0 True False 157573.63905991506 143422.30135713745 137118.28634449563 143165.2026674447 139691.6637829346 141537.3217929485 133935.87173679925 134135.1333872961 140117.49568567058 143395.6292497114 1.098873374902619 1.00018600362902 0.9562236105935676 0.9983930710895977 0.9741696069388094 0.9870406966621917 0.9340303636700197 0.9354199572827362 0.9771392365221102 1.0 17.12964152528371 -4.76738539731607 2.6361618217871463 0.9684566414720945 1.1283276406833045 0.7554165132551188 0.021926300906055372 0.24940468470199417 2.207673414211524 0.005941451267996027 0.0909336505460337 1.7084985033197012e-05 4.76738539731607 0.15987099921120995 IKGS(ph)SPGIQDTLEAEDGAFETDEAPEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 IKGSSPGIQDTLEAEDGAFETDEAPEDR 28 1 Q9UNX4 Q9UNX4 WDR3 WD repeat-containing protein 3 1 IKGS(0.491)S(0.491)PGIQDT(0.018)LEAEDGAFETDEAPEDR;IKGS(0.497)S(0.497)PGIQDT(0.006)LEAEDGAFETDEAPEDR;IKGS(0.5)S(0.5)PGIQDTLEAEDGAFETDEAPEDR;IKGS(0.499)S(0.499)PGIQDT(0.002)LEAEDGAFETDEAPEDR;IKGS(0.5)S(0.5)PGIQDTLEAEDGAFETDEAPEDR;IKGS(0.491)S(0.491)PGIQDT(0.018)LEAEDGAFETDEAPEDR;IKGS(0.499)S(0.499)PGIQDT(0.001)LEAEDGAFETDEAPEDR;IKGS(0.513)S(0.487)PGIQDTLEAEDGAFETDEAPEDR 152.4 1.9459e-12 47388400.0 139855.6 130456.70000000001 148581.5 165856.40000000002 180023.3 168711.8 166926.59999999998 169646.3 153727.40000000002 132488.8 True False 163530.39080598907 143407.57901770523 152124.24645847687 156564.00362170386 144749.0266730721 159864.25620785033 151114.1040040721 165193.2643801131 155975.37240133176 156507.9706592365 1.0448694089966983 0.9162956903322537 0.9719904092916501 1.0003580198646198 0.9248668043126886 1.0214448218482204 0.9655361536384085 1.055494258115371 0.9965969895612258 1.0 17.25587660723516 -7.738018875998245 24.98801197152293 1.0195342477492932 0.9758092112999798 0.1684767774873578 0.03989047818219606 341.06239386761524 363889.4566608082 0.017730603778852588 0.010228439224871783 1.828020762067187e-08 7.738018875998245 -0.04372503644931347 IKGS(ph)SPGIQDTLEAEDGAFETDEAPEDR ddPTM_PC-9_Lapatinib_30min_R1 6 IKGSSPGIQDTLEAEDGAFETDEAPEDR 28 1 Q9UNX4 Q9UNX4 WDR3 WD repeat-containing protein 3 1 IKGS(0.499)S(0.499)PGIQDT(0.002)LEAEDGAFETDEAPEDR;IKGS(0.5)S(0.5)PGIQDTLEAEDGAFETDEAPEDR;IKGS(0.5)S(0.5)PGIQDTLEAEDGAFETDEAPEDR;IKGS(0.498)S(0.498)PGIQDT(0.005)LEAEDGAFETDEAPEDR;IKGS(0.5)S(0.5)PGIQDTLEAEDGAFETDEAPEDR;IKGS(0.5)S(0.5)PGIQDTLEAEDGAFETDEAPEDR 136.26 2.0783e-12 45557900.0 143549.3 119513.6 127040.4 114750.1 117683.9 123040.0 106545.7 115615.5 135933.7 100112.2 True False 141502.26065828258 119236.87360209355 116595.62870212574 123189.20514911195 110761.9643774496 117777.86602024893 112062.11501388618 120987.41820513357 120623.41526068035 117416.46037887856 1.205131377676385 1.015503901389472 0.9930092282282725 1.04916469762081 0.9433256974366603 1.0030779810616346 0.9543986818567429 1.0304127531585627 1.0273126516627533 1.0 16.841275145596512 -4.7606363084523 4.58779135179846 0.9995907493275963 1.2218295960071592 0.7985206375261512 0.030726123636334854 0.08455980581571489 4.040170418919682 0.007628984736537648 0.062100713888281575 1.735256546632022e-05 4.7606363084523 0.22223884667956295 IKGSS(ph)PGIQDTLEAEDGAFETDEAPEDR ddPTM_PC-9_AZD4547_30min_R2 1 IKGSSPGIQDTLEAEDGAFETDEAPEDR 28 1 Q9UNX4 Q9UNX4 WDR3 WD repeat-containing protein 3 1 IKGS(0.229)S(0.756)PGIQDT(0.015)LEAEDGAFETDEAPEDR 113.68 2.5447e-12 17940000.0 36898.0 30980.0 45417.0 62218.0 48670.0 38352.0 34804.0 46531.0 40799.0 48372.0 True False 48630.79647392242 40993.67915308071 44814.740905059385 47874.60135851765 41913.01060535236 35953.84337720164 37901.48857571809 39340.70312600791 42955.55184719069 46678.51100329091 1.0418240734048665 0.8782130850358657 0.9600722032864304 1.025624004054937 0.8979080460042402 0.7702440074548831 0.8119686716880489 0.8428011579725482 0.9202425468147915 1.0 15.510470920834 -6.515049265721223 24.57077346320348 0.8532606096405204 0.9674386007240935 0.32057242503900285 0.07187447757445957 325.73537705929164 1022239.7313103613 0.0227783277915184 0.02379185483309135 3.054574587155193e-07 6.515049265721223 0.11417799108357307 IKIEHAPS(ph)PSSGGTLK ddPTM_PC-9_AZD4547_30min_R2 1 IKIEHAPSPSSGGTLK 16 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YCQ1;A0A2R8Y7Y0 Q14004 CDK13 Cyclin-dependent kinase 13 1 IKIEHAPS(0.725)PS(0.054)S(0.029)GGT(0.191)LK 59.63399999999999 0.022986000000000003 6983000.0 22699.0 21895.0 24799.0 33801.0 30097.0 31299.0 24712.0 29138.0 26672.0 26004.0 True False 29916.809831469585 28972.130569938738 24470.149056621263 26008.701670244227 25918.551062035953 29341.868582160896 26911.3201265126 24635.39162462913 28081.827468032814 25093.60787500159 1.1922083895027664 1.1545621783147793 0.9751546759841807 1.0364672070991536 1.0328746344943158 1.1692965287542987 1.0724372621332712 0.9817397222171094 1.1190828998331526 1.0 14.615032291076595 -5.0869209044819295 6.321182261657484 1.0521227494336647 1.1834689196534265 0.4361411426160834 0.05740099270502312 0.19893370224598358 11.682177789700814 0.014904091755623333 0.041114415383781876 8.186138639222385e-06 5.0869209044819295 0.1313461702197618 IKIEHAPS(ph)PSSGGTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IKIEHAPSPSSGGTLK 16 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YCQ1;A0A2R8Y7Y0 Q14004 CDK13 Cyclin-dependent kinase 13 1 IKIEHAPS(0.993)PS(0.005)S(0.002)GGTLK 78.418 0.017228999999999998 0.0 30764.0 26455.0 27082.0 25268.0 30900.0 18649.0 29961.0 23397.0 22381.0 17951.0 True False 35971.73758330333 29081.277564995886 27727.73758905693 23852.3158799613 24845.366817506005 17671.013610311787 27122.877181144348 22782.85354117064 22708.279784307895 21205.374199962185 1.696350049949483 1.3714107230914956 1.3075806787274886 1.1248240967143053 1.1716542506262544 0.8333271294190743 1.279056758224654 1.0743905448841957 1.0708738063367158 1.0 14.372142321180634 -3.935492540983503 0.6456965787550142 1.0640979327164606 3.168079019302332 0.7597242820255893 0.11030953920639412 4.19418957681814 0.589818986985005 0.04729301277250111 8.350345121132094 0.00011601321412699008 3.935492540983503 2.103981086585871 IKIEHAPS(ph)PSSGGTLK ddPTM_PC-9_Lapatinib_30min_R1 1 IKIEHAPSPSSGGTLK 16 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YCQ1;A0A2R8Y7Y0 Q14004 CDK13 Cyclin-dependent kinase 13 1 IKIEHAPS(0.994)PS(0.004)S(0.001)GGTLK 52.861999999999995 0.033236 5433900.0 43092.0 52431.0 50802.0 52762.0 44144.0 49083.0 48107.0 43716.0 52663.0 42699.0 True False 42477.50017789505 52309.59924085105 46625.255661391 56642.29348887235 41547.536710443244 46983.8345080614 50597.7450706412 45747.204953104214 46731.53837402498 50079.46525715883 0.8482019518333996 1.0445319048883699 0.9310254297239315 1.1310482889146938 0.829632195493622 0.9381856269191111 1.0103491483150029 0.9134922810815093 0.9331477110240257 1.0 15.611931536968465 -6.2903774510737875 24.991148516866712 0.9368224263449133 0.9885701246978693 0.08487925868259716 0.0823974330584666 1868.2897520373006 1613464.631040552 0.024637813863481017 0.027940543073036495 5.124158430254612e-07 6.2903774510737875 0.051747698352956006 IKNENTEGS(ph)PQEDGVELEGLK ddPTM_PC-9_AZD4547_30min_R2 4 IKNENTEGSPQEDGVELEGLK 21 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 IKNENT(0.001)EGS(0.999)PQEDGVELEGLK;IKNENT(0.021)EGS(0.979)PQEDGVELEGLK;IKNENTEGS(1)PQEDGVELEGLK;IKNENTEGS(1)PQEDGVELEGLK 125.05 2.8644e-06 143208000.0 324858.0 298929.0 316036.0 360832.0 333557.0 354079.0 341471.0 344823.0 329570.0 354925.0 True False 428156.08653383516 395551.95337479917 311845.1561457461 277647.7571988277 287248.3681629238 331938.3841561376 371861.2574830207 291538.5285942579 346990.39736950997 342499.18378076144 1.2500937427281693 1.1548989664979685 0.9104989760949697 0.8106523178652418 0.8386833655837134 0.9691654750588137 1.085728886644747 0.8512094112927167 1.0131130636259367 1.0 18.385741024387784 -5.148959053275817 3.6027698870994525 0.9281420373114243 1.23172752134089 0.6332459740119366 0.08252490139680468 0.15395705774273982 3.565887205235901 0.02284301622786853 0.07346204008638131 7.096446724627558e-06 5.148959053275817 0.3035854840294657 IKNENTEGS(ph)PQEDGVELEGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IKNENTEGSPQEDGVELEGLK 21 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 IKNENTEGS(1)PQEDGVELEGLK;IKNENT(0.001)EGS(0.999)PQEDGVELEGLK;IKNENT(0.01)EGS(0.99)PQEDGVELEGLK;IKNENT(0.024)EGS(0.976)PQEDGVELEGLK 102.07 7.118e-05 48571100.0 170233.0 163229.0 150017.0 181607.0 186081.0 169897.0 191585.0 160640.0 139005.0 133808.0 True False 199050.0846449905 179433.29637712045 153593.9742226405 171432.14856783827 149619.76384363545 160987.30223342494 173436.68184471593 156423.37021214908 141037.6851533766 158066.33117645493 1.2592819936004207 1.1351772071992539 0.9717058217235284 1.0845582819054782 0.9465631468134078 1.0184794006113118 1.0972398774227419 0.9896058765198279 0.8922689867200836 1.0 17.270170574469496 -4.962748666024401 2.4153534045563054 1.00442961107081 1.275431789059947 0.6738323922172891 0.057742728552546765 0.22698549449600733 2.171605818167138 0.015532746867053315 0.11025602360598395 1.0895604590171575e-05 4.962748666024401 0.27100217798913695 IKNENTEGS(ph)PQEDGVELEGLK ddPTM_PC-9_Lapatinib_30min_R1 4 IKNENTEGSPQEDGVELEGLK 21 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 IKNENTEGS(1)PQEDGVELEGLK;IKNENT(0.005)EGS(0.995)PQEDGVELEGLK;IKNENTEGS(1)PQEDGVELEGLK;IKNENT(0.001)EGS(0.999)PQEDGVELEGLK 151.42 2.5003e-05 158422000.0 334043.0 368814.0 352498.0 349253.0 358293.0 374694.0 358761.0 327530.0 337827.0 289491.0 True False 329279.48556401586 367960.0338428641 323516.97512162954 374938.2306938539 337218.910171141 358669.21107437497 377335.88914894505 342748.2395070511 299777.3657839799 339529.13362748944 0.9698121691238465 1.0837362611909684 0.9528401043681057 1.1042888328552483 0.993195801987104 1.0563724156522156 1.1113505492666642 1.0094810888396206 0.8829208927705074 1.0 18.37317584606911 -8.01394862049352 24.00206703888822 0.9430405847760324 1.0402161948324897 0.3093515107920427 0.05742943207509707 418.91997623405007 720849.9920405174 0.03358295674582708 0.013837233638394732 9.683924158133764e-09 8.01394862049352 0.09717561005645736 IKPNLSSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 IKPNLSSSPR 10 1 Q96JN0-3;A0A1P0AZG4 Q96JN0-3 LCOR Ligand-dependent corepressor 1 IKPNLS(0.001)S(0.14)S(0.859)PR 64.827 0.023781 33558000.0 135730.0 113910.0 205710.0 249130.0 224490.0 170380.0 164200.0 195990.0 159020.0 190480.0 True False 178889.3166406167 150729.1798685419 202982.15099147367 191696.92752013076 193323.43847946526 159726.11166582265 178813.4819024512 165704.2489021573 167425.47255423566 183811.3531775994 0.9732223475215537 0.82002105562493 1.1042960485435922 1.0429003660884444 1.0517491718407364 0.8689676067587323 0.9728097792179395 0.9014908276207132 0.9108549045524319 1.0 17.48786635241946 -6.759714386867091 24.999550192675628 0.9272918773743078 0.9968769068248698 0.15867704618590406 0.0775896146269788 93.5001771879671 1355063.7983659536 0.027562127155832176 0.026201134834716797 1.7389440668142546e-07 6.759714386867091 0.069585029450562 IKQSS(ph)QDNELK ddPTM_PC-9_Lapatinib_30min_R1 1 IKQSSQDNELK 11 1 Q13427;E9PG73 Q13427 PPIG Peptidyl-prolyl cis-trans isomerase G 1 IKQS(0.238)S(0.762)QDNELK 63.16 0.024538 11728000.0 29157.0 24435.0 27143.0 30883.0 26850.0 28325.0 21977.0 18721.0 23824.0 20632.0 True False 28741.21583326105 24378.422258781913 24911.407315009954 33154.238842667924 25270.73578913105 27113.605778799963 23114.861525713142 19590.846004370578 21140.690242158096 24198.213709588075 1.1877412183475715 1.0074471839680643 1.029472985650147 1.3701110024303653 1.0443223657917364 1.1204796397040133 0.9552300761999769 0.8095988505386281 0.873646728468288 1.0 14.562612932527207 -7.361235868801193 3.094253368223473 0.8804316314684968 1.1258141254079308 0.5022927558339619 0.10652816900357415 0.2177663658514675 3.9999622429188157 0.05024315956747166 0.03199521653423993 4.352754079282097e-08 7.361235868801193 0.245382493939434 IKTEPS(ph)SPLSDPSDIIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IKTEPSSPLSDPSDIIR 17 1 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 IKT(0.001)EPS(0.499)S(0.499)PLSDPSDIIR 158.45 4.6503e-17 0.0 9155.3 5015.0 6823.3 10810.0 13758.0 10828.0 10891.0 15056.0 13023.0 9348.0 True False 10705.111464582533 5512.856057019632 6985.993349509355 10204.350746492866 11062.218662629364 10260.16061839541 9859.325635988225 14660.795953150628 13213.436737904543 11042.718401272714 0.9694271895359325 0.4992299773201004 0.6326334780667949 0.924079594868305 1.001765893202022 0.929133592432538 0.8928350137817426 1.327643739557908 1.1965746347730506 1.0 13.430807745621623 -6.559992735428535 0.7630798174883534 1.1530437519936145 0.6819859182139334 0.4843363503942496 0.16306603301493047 0.5607996553228419 0.7267396806929106 0.10889757252875258 0.13292274165971432 2.7542747745166473e-07 6.559992735428535 -0.47105783377968113 IKTEPSS(ph)PLSDPSDIIR ddPTM_PC-9_AZD4547_30min_R2 2 IKTEPSSPLSDPSDIIR 17 1 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 IKTEPS(0.005)S(0.978)PLS(0.014)DPS(0.003)DIIR;IKTEPS(0.003)S(0.96)PLS(0.022)DPS(0.015)DIIR 137.39 2.7986999999999998e-05 26825000.0 76255.0 62456.0 98039.0 159165.0 153096.0 106941.0 91921.0 106333.0 89656.0 110050.0 True False 100502.50379746764 82643.68060635278 96738.93880245532 122471.96832473668 131841.26302932025 100253.96236444829 100101.79092542744 89901.67813925774 94395.03312364842 106197.18299661286 0.9463763629273777 0.778209725289876 0.9109369577678985 1.153250631221008 1.2414760854205078 0.9440359860359562 0.9426030719536146 0.8465542644584568 0.8888656973759759 1.0 16.696385971928045 -10.679283237950651 14.761499129100399 1.000000000005625 0.9639409726323321 0.0074616196923918965 0.13066957324412615 0.0 0.0 0.142815370614994 0.03463781517690312 2.0927471639283017e-11 10.679283237950651 -0.03605902737329292 IKTEPSS(ph)PLSDPSDIIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IKTEPSSPLSDPSDIIR 17 1 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 IKTEPS(0.286)S(0.698)PLS(0.013)DPS(0.003)DIIR;IKTEPS(0.037)S(0.954)PLS(0.009)DPSDIIR 92.098 0.00099266 20336000.0 64717.0 34919.0 58530.0 81398.0 94635.0 92061.0 99819.0 101109.0 95662.0 76495.0 True False 75672.30988098563 38385.527548368584 59925.577176261075 76837.53395587667 76091.95109303157 87233.15909587183 90363.42169302268 98454.99588384086 97060.8757752762 90362.93796591327 0.8374264005175525 0.42479282339014235 0.6631654362418608 0.8503213340059986 0.8420703532429966 0.9653643524602746 1.0000053531582782 1.0895506288317018 1.0741226210671628 1.0 16.463443557318385 -6.306267425880365 0.9512689581290978 1.053149864338436 0.608852408353519 0.7124579688738439 0.10394602862284687 0.2880720919449897 0.5566245373499652 0.04978077529533073 0.0751055894107813 4.940063985726979e-07 6.306267425880365 -0.4442974559849171 IKTEPSS(ph)PLSDPSDIIR ddPTM_PC-9_Lapatinib_30min_R1 1 IKTEPSSPLSDPSDIIR 17 1 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 IKTEPS(0.047)S(0.866)PLS(0.047)DPS(0.04)DIIR 101.62 0.00049229 14900000.0 96140.0 51766.0 72261.0 43575.0 63549.0 66624.0 49600.0 42880.0 64963.0 51585.0 True False 94769.02597008322 51646.139007493555 66319.97951552633 46779.65086193877 59811.172762141105 63774.64682812951 52168.045305336105 44872.361341136195 57646.18284928292 60501.39851730808 1.5663939725785339 0.8536354575790304 1.0961726694062068 0.7731994963481079 0.9885915735490062 1.054102027242974 0.8622618085499628 0.7416747784482904 0.9528074434972219 1.0 15.884680870873302 -4.757778186551953 24.999252605306122 0.921354292832988 1.5663948866826678 0.7519791311883912 0.11054009973931224 51.550671742489406 351944.70979993657 0.027427299409851696 0.1981301413606217 1.7467140494479962e-05 4.757778186551953 0.6450405938496798 ILAHNNFVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ILAHNNFVGR 10 0 O00425;Q9NZI8-2;Q9NZI8 O00425;Q9NZI8 IGF2BP3;IGF2BP1 Insulin-like growth factor 2 mRNA-binding protein 3;Insulin-like growth factor 2 mRNA-binding protein 1 0 138.06 3.88e-06 0.0 11846.0 10106.0 13295.0 11478.0 12849.0 14562.0 12201.0 13754.0 11039.0 8919.9 False True 13851.293830835104 11109.256891772755 13612.003221568273 10834.924872178075 10331.330687318268 13798.343085064085 11045.23295240954 13392.97207356761 11200.424491263782 10537.007260110457 1.3145377514611207 1.054308554368055 1.291828209428944 1.0282734560879951 0.9804805512879534 1.3095125346738579 1.0482324515636479 1.271041363354552 1.0629606884361558 1.0 13.363177547844584 -14.522878745271548 0.23652041041807367 0.1751857275095219 1.164143649661289 0.12818087419307334 0.12474744699183068 379.68388728493267 3.784465598083992 150.5552710004193 0.19460271353874817 3.000000000060716e-15 14.522878745271548 0.988957922151767 ILAHNNFVGR ddPTM_PC-9_Lapatinib_30min_R1 1 ILAHNNFVGR 10 0 O00425;Q9NZI8-2;Q9NZI8 O00425;Q9NZI8 IGF2BP3;IGF2BP1 Insulin-like growth factor 2 mRNA-binding protein 3;Insulin-like growth factor 2 mRNA-binding protein 1 0 149.57 0.00013163 3596500.0 16585.0 18293.0 21728.0 16214.0 13882.0 17260.0 17112.0 16378.0 20111.0 16757.0 False True 16348.494858683498 18250.64368241858 19941.607712505498 17406.43164831841 13065.488053062087 16521.83003502515 17997.975630340963 17138.981670828554 17845.887401781456 19653.42512270101 0.8318394761531872 0.9286240728257527 1.01466322475626 0.8856691156704704 0.6647944554952195 0.84065906740812 0.9157678887000774 0.8720608018106673 0.9080293786129051 1.0 14.262493141240736 -10.124953870016023 9.692736473296415 0.9999908858516292 0.8737812136173624 0.16563813789482185 0.08512768706787179 0.0 0.0 0.08983168006159568 0.021787382671803007 7.499738659860625e-11 10.124953870016023 -0.12620967223426682 ILAT(ph)PPQEDAPSVDIANIR ddPTM_PC-9_AZD4547_30min_R2 5 ILATPPQEDAPSVDIANIR 19 0 P29401;P29401-2;A0A0B4J1R6;E9PFF2 P29401 TKT Transketolase 1 ILAT(0.999)PPQEDAPS(0.001)VDIANIR;ILAT(0.999)PPQEDAPS(0.001)VDIANIR;ILAT(0.868)PPQEDAPS(0.132)VDIANIR;ILAT(1)PPQEDAPSVDIANIR;ILAT(0.994)PPQEDAPS(0.006)VDIANIR 179.67 1.3891e-08 17522500.0 153980.3 144671.30000000002 191389.5 263079.4 225184.6 199993.9 168639.1 221650.0 171474.5 198354.9 True False 202942.8324107949 191433.46852353407 188851.55017832218 202430.5088662126 193921.60525913318 187488.2498173689 183647.65320277456 187399.08551029742 180538.29199787002 191410.55532553254 1.0602489087691604 1.0001197070765642 0.9866308044357416 1.0575723398426926 1.0131186596754296 0.9795084158159775 0.9594437093108288 0.9790425882814414 0.9431992488127312 1.0 17.546310863800542 -6.774461985764032 3.502024003483921 0.9689132754662816 1.0228823222006633 0.5159933438814184 0.025065717096167055 0.19602064994115032 5.074467054990368 0.008983910670365563 0.008307347691066062 1.6808850488408902e-07 6.774461985764032 0.05396904673438174 ILAT(ph)PPQEDAPSVDIANIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ILATPPQEDAPSVDIANIR 19 0 P29401;P29401-2;A0A0B4J1R6;E9PFF2 P29401 TKT Transketolase 1 ILAT(1)PPQEDAPSVDIANIR;ILAT(0.998)PPQEDAPS(0.002)VDIANIR;ILAT(1)PPQEDAPSVDIANIR;ILAT(1)PPQEDAPSVDIANIR;ILAT(0.631)PPQEDAPS(0.369)VDIANIR 130.95 2.8278e-06 14187100.0 98963.1 93553.1 107936.3 120664.1 122860.0 108469.4 106844.70000000001 89765.7 99146.9 84340.90000000001 True False 115715.598219679 102840.43349710113 110509.91074269741 113903.6816752903 98786.46495788965 102781.0737145345 96723.59652735962 87409.44548962079 100596.7358449933 99631.23752780288 1.1614389331196218 1.0322107408171328 1.1091893816119542 1.1432527036864777 0.9915210069565031 1.0316149459234876 0.9708159702459597 0.8773297176523427 1.0096907189065176 1.0 16.604310523056384 -6.625204513822618 1.4402858548822604 0.9584741895053207 1.1054641056351977 0.5903909536091019 0.051959603196698664 0.2787284137271927 1.2001261281368294 0.02214096775466226 0.02251131644701659 2.3702572638261e-07 6.625204513822618 0.146989916129877 ILAT(ph)PPQEDAPSVDIANIR ddPTM_PC-9_Lapatinib_30min_R1 5 ILATPPQEDAPSVDIANIR 19 0 P29401;P29401-2;A0A0B4J1R6;E9PFF2 P29401 TKT Transketolase 1 ILAT(1)PPQEDAPSVDIANIR;ILAT(1)PPQEDAPSVDIANIR;ILAT(0.957)PPQEDAPS(0.043)VDIANIR;ILAT(0.984)PPQEDAPS(0.016)VDIANIR;ILAT(0.923)PPQEDAPS(0.077)VDIANIR 188.9 9.856700000000001e-11 20121700.0 170489.0 159902.0 182549.0 148284.0 166662.0 171941.0 142397.0 159442.0 176477.0 130039.0 True False 168057.79559614646 159531.75674334978 167540.52587951795 159189.30002092302 156859.2688300989 164587.4842440473 149769.619906128 166850.25739163806 156600.30187480405 152516.06788392455 1.101902231862221 1.0459996704397378 1.0985106566412928 1.0437542891682552 1.028477005776728 1.079148489254981 0.9819924024012553 1.0939847827615308 1.0267790407105688 1.0 17.21860171603251 -1.522878745299237 0.09414497304618594 0.9779623212377929 1.2767720170146146 0.3080212932217895 0.03328854081902731 192.03136030105122 1.2972823715492106 0.5086193385303335 7.404501477028748 0.029999999998694477 1.522878745299237 0.2988096957768217 ILATDVSSKNT(ph)PDSK ddPTM_PC-9_Lapatinib_30min_R1 2 ILATDVSSKNTPDSK 15 1 H0Y8J2;Q03188;Q03188-2 H0Y8J2 CENPC Centromere protein C 1 ILAT(0.004)DVS(0.007)S(0.078)KNT(0.891)PDS(0.02)K;ILAT(0.001)DVS(0.003)S(0.015)KNT(0.793)PDS(0.188)K 78.501 0.0085289 20609700.0 122273.0 92087.0 80877.0 81788.0 92849.0 90547.0 75389.0 86679.0 82666.0 59508.0 True False 120529.36459787788 91873.77820930826 74227.60525424842 87802.96235676987 87387.80436815754 86674.51588536633 79292.27353879 90706.42277724663 73355.28456842854 69793.87851057423 1.7269331805312538 1.3163586860327412 1.063526011711793 1.258032426776041 1.2520840829173538 1.2418641539205273 1.1360920933313186 1.2996329293192097 1.0510274845567544 1.0 16.09081288547262 -4.79993241088074 3.1871756973463783 1.1817865416588342 1.7947537078582891 0.7497279593583264 0.09776693977282387 0.15126640274190456 2.3919775957963 0.023357794623174263 0.22854074769584865 1.5851398681052718e-05 4.79993241088074 0.6129671661994549 ILATPPQEDAPS(ph)VDIANIR ddPTM_PC-9_AZD4547_30min_R2 1 ILATPPQEDAPSVDIANIR 19 0 P29401;P29401-2;A0A0B4J1R6;E9PFF2 P29401 TKT Transketolase 1 ILAT(0.006)PPQEDAPS(0.994)VDIANIR 116.6 6.681e-05 9403200.0 21613.0 22881.0 32248.0 37229.0 34708.0 26819.0 23200.0 34393.0 25378.0 29662.0 True False 28485.484421672834 30276.835787657845 31820.37044953111 28646.429232316274 29889.393303689558 25142.00369037263 25264.755055644724 29078.35212251595 26719.42926978616 28623.542408410143 0.9951767679636765 1.0577599150956918 1.1116852692621888 1.0007995804145962 1.044224117239503 0.8783679997268762 0.8826564753991266 1.015889358054165 0.9334773763688831 1.0 14.804914608524998 -6.7379631926587376 24.637613727796605 0.9393574788395347 1.0443990435514028 0.49329562215583866 0.050530851393281576 168.67825503699558 177022.66000894672 0.017147550115008212 0.01713698627625664 1.8282551579225227e-07 6.7379631926587376 0.1050415647118681 ILATPPQEDAPS(ph)VDIANIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ILATPPQEDAPSVDIANIR 19 0 P29401;P29401-2;A0A0B4J1R6;E9PFF2 P29401 TKT Transketolase 1 ILAT(0.254)PPQEDAPS(0.746)VDIANIR 134.04 5.3747e-05 4957000.0 72607.0 68258.0 82472.0 95698.0 92142.0 94040.0 90875.0 83181.0 73172.0 64828.0 True False 84897.9310463821 75034.20313859345 84438.44525680158 90336.3513171023 74087.43654688157 89108.37685204143 82266.6621219749 80997.58688755448 74242.0020721762 76580.80322183429 1.108605910027547 0.9798043371422895 1.1026058973579291 1.1796213609228128 0.9674413616721922 1.163586344137944 1.0742465299517714 1.0576748150959705 0.969459694188853 1.0 16.224695171600672 -8.12848741076177 3.6511667590009345 0.9851042552644357 1.0809273564317758 0.26119007155130514 0.0644487094938995 0.3365102830191122 7.698547280942622 0.04889764283157671 0.01645053961685524 7.4389662651591365e-09 8.12848741076177 0.09582310116734016 ILATPPQEDAPSVDIANIR ddPTM_PC-9_Lapatinib_30min_R1 4 ILATPPQEDAPSVDIANIR 19 0 P29401;P29401-2;A0A0B4J1R6;E9PFF2 P29401 TKT Transketolase 0 ;;; 217.39 3.43e-27 63588900.0 253424.0 266198.0 231971.0 251807.0 255098.0 287683.0 258335.0 217646.0 224873.0 231563.0 False True 249810.1272877306 265581.6348861567 212899.2398139553 270325.7267835273 240093.63718196444 275379.46871182736 271710.32225713733 227758.62771578613 199545.43472233115 271588.3560116982 0.9198116257862339 0.977882994640305 0.7839041516374327 0.9953509449126879 0.8840350915914187 1.0139590399080507 1.0004490849579497 0.8386170565647366 0.7347348673289074 1.0 18.05106210172091 -7.787597512273389 24.47451589307867 0.8400068206441409 0.9377427266389469 0.14252842605167693 0.08844503498666499 293.11716886003694 274246.04264863674 0.046705181003649676 0.022449060559449913 1.630806702587397e-08 7.787597512273389 0.09773590599480597 ILCKS(ph)PQSDPADTPTNTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ILCKSPQSDPADTPTNTK 18 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ILCKS(0.879)PQS(0.12)DPADTPTNTK 52.019 0.027364999999999997 5684700.0 23484.0 21988.0 16924.0 35566.0 40951.0 30976.0 38765.0 49355.0 34637.0 22842.0 True False 27459.377369857477 24170.823326370424 17327.532344627416 33573.35232652776 32926.945519213215 29351.564029868514 35092.8985657041 48059.48354594509 35143.500598233855 26983.073782827483 1.0176519395404509 0.8957772387574752 0.6421630272402461 1.2442375022483336 1.2202814914351425 1.0877768880633747 1.3005522961597449 1.7810974365911942 1.3024276211481813 1.0 14.719767082122216 -6.330041928984254 1.0161106082294127 1.3786766029501896 0.865816612761874 0.37362041816231595 0.22724339487583006 0.522187407673049 1.1427441293296576 0.10892843627032961 0.15628426078488866 4.676899859524713e-07 6.330041928984254 -0.5128599901883155 ILCKS(ph)PQSDPADTPTNTK ddPTM_PC-9_Lapatinib_30min_R1 1 ILCKSPQSDPADTPTNTK 18 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 ILCKS(0.867)PQS(0.124)DPADT(0.008)PT(0.001)NTK 59.57899999999999 0.013444 6270200.0 38576.0 45651.0 36542.0 15328.0 21510.0 30493.0 48722.0 40980.0 25441.0 16862.0 True False 38025.899166028015 45545.2979142891 33537.657816199164 16455.272252709052 20244.824090287108 29188.885472654805 51244.5867614231 42884.08040484517 22575.56667439322 19776.574232797324 1.922774830383219 2.3029922866396704 1.695827468469264 0.8320587812129641 1.023676995417803 1.4759323393961818 2.591176113628389 2.1684281564663777 1.1415307023677572 1.0 14.271504918619462 ILDAVVAQEPLHR ddPTM_PC-9_Lapatinib_30min_R1 1 ILDAVVAQEPLHR 13 0 K7EJ74;K7EP67;Q15029-2;Q15029-3;Q15029 K7EJ74 EFTUD2 116 kDa U5 small nuclear ribonucleoprotein component 0 76.72800000000001 0.014196 2768200.0 14999.0 14218.0 19729.0 14190.0 19043.0 17775.0 16836.0 15040.0 14510.0 14767.0 False True 14785.111509520268 14185.079094551318 18106.957776142353 15233.579936452345 17922.928179978488 17014.80468554878 17707.68570081932 15738.813306219397 12875.731002926197 17319.456274209337 0.8536706508238945 0.8190256593490486 1.0454691815646486 0.8795645599531261 1.034843582628387 0.9824098641529401 1.022415797613006 0.9087359936152443 0.7434258211731302 1.0 14.080106018458496 -5.234578027539537 24.898681818586653 0.9528058705753235 0.836348118354123 0.2222588372296147 0.08660975310464888 1086.2613754165852 1006888.1837307721 0.022240200795189395 0.058807162497652075 5.826690801226105e-06 5.234578027539537 -0.11645775222120047 ILDEIEEHNIK ddPTM_PC-9_AZD4547_30min_R2 1 ILDEIEEHNIK 11 0 Q15019-2;Q15019-3;Q15019;B5MCX3;H7C2Y0;C9J2Q4 Q15019-2 SEPT2 Septin-2 0 77.305 0.016492 2042900.0 8882.0 6850.5 12015.0 18358.0 12911.0 13027.0 9388.3 11101.0 10297.0 10126.0 False True 11706.29124292316 9064.790156171059 11855.67324953846 14125.846728272645 11118.530510082279 12212.41963065306 10223.840512452993 9385.595525602583 10841.278398257868 9771.49182211452 1.1980045069914367 0.9276771982406947 1.2132920402908274 1.4456182316300457 1.1378539441561202 1.2498009365380947 1.0462926949715838 0.9605079445864562 1.1094803736848289 1.0 13.254363121171576 -7.352375192504699 5.877344267655601 1.022849789636955 1.1925005610269652 0.30281322451499526 0.12372542906075937 0.3304373374400403 17.21915886218855 0.056241730930608066 0.037566265541639686 4.4424731076082246e-08 7.352375192504699 0.16965077139001017 ILDEIEEHNIK ddPTM_PC-9_Lapatinib_30min_R1 4 ILDEIEEHNIK 11 0 Q15019-2;Q15019-3;Q15019;B5MCX3;H7C2Y0;C9J2Q4 Q15019-2 SEPT2 Septin-2 0 ;;; 124.1 0.00065543 5070500.0 48794.9 43923.6 51804.2 50663.3 50503.1 51221.6 48066.7 45641.2 51121.3 48166.2 False True 48099.075778111226 43821.89760285795 47545.058645994905 54389.248089814384 47532.606950914866 49030.97157138145 50555.35853383058 47761.856773392356 45363.480862845696 56491.663492572734 0.8514367041861862 0.7757232641701098 0.8416296442084045 0.962783616682933 0.8414092277024952 0.8679328690299202 0.8949171507487537 0.8454673454548186 0.8030119500518847 1.0 15.785750363443674 -12.032061173818665 2.307877941419715 3.1648752951290553 0.8553764254836693 0.4568388490590519 0.04779317163848161 5589048.816785402 751717.5650344854 62657602.62539558 0.012431449269571617 9.288355437195712e-13 12.032061173818665 -2.309498869645386 ILDLIESGK ddPTM_PC-9_Lapatinib_30min_R1 2 ILDLIESGK 9 0 P00352 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ; 120.12 0.0078156 41004000.0 525490.0 407200.0 427840.0 394170.0 415330.0 318770.0 439590.0 400980.0 341870.0 478610.0 False True 517996.4162369358 406257.15341829363 392664.6467101606 423158.57671257324 390901.10597019736 305136.9501891636 462349.8192696106 419610.9946494582 303365.00054930244 561337.1007922612 0.922790272557871 0.7237311641167304 0.6995166472267034 0.753840385955845 0.6963749686569558 0.5435894932982316 0.8236580454366161 0.7475205078325069 0.5404328346035537 1.0 19.09850788980318 -9.893216042162875 11.735030271345614 0.9999999999791092 0.7159586521036344 0.37938403579053304 0.10864822441336898 0.0 0.0 0.1035313471444847 0.02511003999054117 1.2787450272104672e-10 9.893216042162875 -0.28404134787547475 ILDPNTGEPAPVLSSPPPADVSTFLAFPS(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ILDPNTGEPAPVLSSPPPADVSTFLAFPSPEK 32 0 P46060 P46060 RANGAP1 Ran GTPase-activating protein 1 1 ILDPNTGEPAPVLSSPPPADVS(0.161)T(0.188)FLAFPS(0.651)PEK 105.05 9.4811e-16 3429400.0 44334.0 42517.0 35710.0 48537.0 51449.0 40397.0 48165.0 50593.0 43944.0 40933.0 True False 51838.87056358634 46737.80677493593 36561.46183092916 45817.629249077145 41367.937779736756 38278.510205145845 43602.46251559754 49264.98735771454 44586.59786611972 48353.82887455029 1.072073748246032 0.9665792319403086 0.7561234070167354 0.947549145858685 0.8555255859274804 0.7916334878972261 0.9017375362087716 1.0188435642920475 0.9220903267411499 1.0 15.561342512883758 -7.6673277687469374 7.323439527900475 0.9774245364597535 0.8913859941977288 0.15159510837627743 0.08735789147284287 0.4304230970195256 28.64220287425398 0.04314618479867909 0.02468584206115673 2.1511576100834155e-08 7.6673277687469374 -0.08603854226202468 ILDSVGIEADDDR ddPTM_PC-9_Lapatinib_30min_R1 2 ILDSVGIEADDDR 13 0 P05387 P05387 RPLP2 60S acidic ribosomal protein P2 0 ; 169.58 0.0011560000000000001 11507600.0 20414.2 30191.0 38287.0 32635.0 37776.0 33905.0 34548.0 35735.0 29424.0 32022.0 False True 20123.08976449421 30121.094594429516 35139.19065209396 35035.08676716857 35554.089950473535 32454.962186415276 36336.72639533775 37395.378557031254 26109.959271543805 37556.96003336706 0.5358018792419854 0.8020109872489352 0.9356239328442701 0.9328520395698171 0.9466711341622406 0.8641530666374762 0.9675097868159401 0.9956976955485148 0.695209602916389 1.0 15.196792671447465 -4.785720400764133 2.3160558773140427 0.9184697417221923 0.44318170194237877 0.6577758822178325 0.08338656759536871 0.3407683255617654 2.215655916597186 0.02093355226200479 0.3333126930909889 1.6378706448808223e-05 4.785720400764133 -0.47528803977981354 ILDSVGIEADDDRLNK ddPTM_PC-9_AZD4547_30min_R2 2 ILDSVGIEADDDRLNK 16 1 P05387 P05387 RPLP2 60S acidic ribosomal protein P2 0 ; 122.12 8.251299999999999e-05 48194000.0 156875.0 154902.0 197573.0 261970.0 251380.0 254170.0 216220.0 206613.0 205724.0 203265.0 False True 206757.98679729423 204971.04222629167 194953.0529280949 201576.86389615337 216480.22613465096 238276.70972004975 235463.16112635747 174685.70834441253 216598.1506461301 196148.7542190512 1.054087687788193 1.0449775377996442 0.993904109685953 1.0276734343723657 1.1036533318630941 1.2147755445540669 1.2004315911351724 0.8905777099625646 1.10425453125357 1.0 17.58158864702896 -3.24273186525211 18.68372755747015 1.066083324850567 0.6334083080139752 0.0 0.09245058912934771 0.0 0.0 0.02225557513819983 0.0 0.0005718315782809394 3.24273186525211 -0.4326750168365918 ILDSVGIEADDDRLNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ILDSVGIEADDDRLNK 16 1 P05387 P05387 RPLP2 60S acidic ribosomal protein P2 0 141.59 3.1236e-05 27194000.0 94590.0 69452.0 81398.0 117410.0 110150.0 93876.0 102990.0 99709.0 77454.0 82034.0 False True 110602.21876234087 76346.73556772228 83338.83702363414 110831.89834835609 88566.89821839123 88952.97730074695 93234.04161697043 97091.74440041813 78586.61822142813 96906.11481921317 1.1413337431665584 0.7878422915845279 0.8599956481498617 1.1437038679666673 0.9139454035859401 0.9179294564300355 0.9621068989393156 1.001915561072191 0.8109562370551986 1.0 16.564300082764817 -9.686163281980035 9.653621508907177 0.9999999999998826 0.9472537192088168 0.0172170551157671 0.1153432202997725 0.0 0.0 0.10760188092344283 0.026097289444852286 2.0598553225163618e-10 9.686163281980035 -0.0527462807910658 ILDSVGIEADDDRLNK ddPTM_PC-9_Lapatinib_30min_R1 2 ILDSVGIEADDDRLNK 16 1 P05387 P05387 RPLP2 60S acidic ribosomal protein P2 0 ; 190.24 3.2006e-08 70696000.0 226830.0 195846.0 218430.0 209203.0 225500.0 220916.0 231520.0 190413.0 220017.0 203009.0 False True 223595.36260447215 195392.5306197422 200471.52856418336 224588.48650075018 212236.5333500576 211467.93766034875 243506.97276394002 199260.28311683206 195236.3685782782 238098.8351575109 0.9390863355402633 0.8206362307084915 0.841967699806529 0.9432573928897083 0.891379973403295 0.8881519202748519 1.0227138347940739 0.8368805457826547 0.8199803600430147 1.0 17.861201037016528 -5.752194438633476 24.993261526309162 0.9102590995528137 0.8625707033289959 0.09273422632244566 0.06648746286294506 500.32257747500097 1352584.7972030067 0.01820218417937759 0.03098689734361229 1.7693166375611918e-06 5.752194438633476 -0.04768839622381782 ILEGPQQS(ph)LSGSPLQPIPAS(ph)PPPQIPPGLRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ILEGPQQSLSGSPLQPIPASPPPQIPPGLRPR 32 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 2 ILEGPQQS(0.47)LS(0.337)GS(0.193)PLQPIPAS(1)PPPQIPPGLRPR 89.434 5.7781e-09 2023300.0 1053.8 1224.4 1334.8 1397.7 1819.7 1488.0 2249.5 2126.9 2782.3 2508.3 True False 1232.187526501269 1345.9503402222997 1366.6266942571897 1319.39140040454 1463.1428478257496 1409.966660525708 2036.4110750303466 2071.0711286368287 2822.9858739055367 2963.0349343081266 0.41585318898340523 0.4542472060109481 0.4612253059973791 0.44528378154698334 0.4937987166079079 0.47585218932119594 0.6872720437586916 0.6989695277151456 0.9527345902064798 1.0 11.532859920497557 -7.873062718989175 0.9189201850906471 1.0129160114563558 0.4436273729005326 0.9651664772228504 0.03852819023462138 0.08570117290218085 0.13375965738771767 0.0325102345588385 0.013047000025998932 1.3394832309020495e-08 7.873062718989175 -0.5692886385558231 down ILEGPQQS(ph)LSGSPLQPIPASPPPQIPPGLRPR ddPTM_PC-9_Lapatinib_30min_R1 2 ILEGPQQSLSGSPLQPIPASPPPQIPPGLRPR 32 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 ILEGPQQS(0.561)LS(0.142)GS(0.296)PLQPIPAS(0.001)PPPQIPPGLRPR;ILEGPQQS(0.64)LS(0.194)GS(0.159)PLQPIPAS(0.007)PPPQIPPGLRPR 75.005 3.5850000000000004e-07 93953000.0 67020.0 52295.0 56836.0 41676.0 48779.0 53181.0 49280.0 30135.6 52945.0 35702.0 True False 66064.28251003711 52173.914140495195 52163.163473304565 44740.99206706047 45909.91512320384 50906.57260096597 51831.47727110812 31535.809991416576 46981.77656443336 41873.04313007532 1.577728236871001 1.2460024454974774 1.2457457011486792 1.0684915335165894 1.0964074185052253 1.215736158531127 1.237824466449637 0.7531291645905233 1.1220053058596235 1.0 15.353734149529537 -1.5228787452803576 0.48665381750018927 1.041136809333496 15.636349945675716 0.5909629803118038 0.12843500674908145 75.50112515095708 0.8316452810507483 0.07510597389518892 1118.7606143713074 0.029999999999998615 1.5228787452803576 14.59521313634222 ILEGPQQSLSGS(ph)PLQPIPAS(ph)PPPQIPPGLRPR ddPTM_PC-9_AZD4547_30min_R2 1 ILEGPQQSLSGSPLQPIPASPPPQIPPGLRPR 32 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 2 ILEGPQQS(0.012)LS(0.212)GS(0.776)PLQPIPAS(1)PPPQIPPGLRPR 109.54 2.6284000000000003e-15 3510900.0 1824.6 2595.2 3118.3 4525.2 3954.1 3443.2 2365.6 3425.9 1927.9 2287.3 True False 2404.7848459623488 3434.0476480979705 3076.9493045389745 3481.985053643065 3405.1414677342045 3227.8961596886916 2576.133817225567 2896.505874350229 2029.8048581141425 2207.2223231999365 1.0895073054879196 1.5558231773949418 1.3940368725875085 1.57754160831204 1.5427269976128077 1.4624245712634085 1.1671383485696167 1.3122855110268181 0.9196195765052876 1.0 11.10801623753468 -7.867934050400386 1.225620574359482 0.9692305590256908 1.4477504442268998 0.5640246812680124 0.15249150066008427 0.33794664861093343 0.9151962072945057 0.131089510391964 0.04814291173831835 1.3553952196756823e-08 7.867934050400386 0.478519885201209 ILEGPQQSLSGS(ph)PLQPIPAS(ph)PPPQIPPGLRPR ddPTM_PC-9_Lapatinib_30min_R1 1 ILEGPQQSLSGSPLQPIPASPPPQIPPGLRPR 32 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 2 ILEGPQQS(0.037)LS(0.238)GS(0.726)PLQPIPAS(1)PPPQIPPGLRPR 75.33800000000001 2.3549e-06 2149100.0 3965.9 3950.0 5457.6 3035.3 4126.5 3704.3 5658.6 2358.4 5031.0 3857.1 True False 3909.3455387430113 3940.854017687276 5008.897194945228 3258.526087463973 3883.787383011143 3545.875724145058 5951.574620257557 2467.9798737624883 4464.355801221347 4523.79459573731 0.8641739707692999 0.871139025940893 1.1072335599996121 0.7203081436399484 0.8585242545430257 0.7838277466192369 1.3156155732326171 0.5455552460511848 0.9868608546966364 1.0 12.14331770947199 ILEGPQQSLSGS(ph)PLQPIPASPPPQIPPGLRPR ddPTM_PC-9_AZD4547_30min_R2 1 ILEGPQQSLSGSPLQPIPASPPPQIPPGLRPR 32 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 ILEGPQQS(0.05)LS(0.172)GS(0.673)PLQPIPAS(0.105)PPPQIPPGLRPR 74.382 3.8336999999999997e-07 41076000.0 21526.0 20042.0 22600.0 35440.0 35476.0 20910.0 28492.0 25963.0 20619.0 33367.0 True False 28370.82023138526 26520.184557328714 22300.309233422337 27269.85554254182 30550.7697603345 19602.49439448495 31027.732803682316 21951.01492038734 21708.87824547721 32198.831486124353 0.8811133485887921 0.823638105275877 0.6925813206306058 0.8469206577975785 0.9488161014010691 0.6087952105632274 0.9636291558298721 0.6817332774901111 0.6742132320805604 1.0 14.974720712617207 ILEGPQQSLSGS(ph)PLQPIPASPPPQIPPGLRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ILEGPQQSLSGSPLQPIPASPPPQIPPGLRPR 32 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 ILEGPQQS(0.25)LS(0.207)GS(0.531)PLQPIPAS(0.011)PPPQIPPGLRPR 40.044000000000004 0.031017000000000003 33751000.0 0.0 4338.5 3122.5 3124.3 3040.0 2787.9 3171.5 0.0 4159.3 2746.3 True False 0.0 4769.197607852379 3196.9522421471925 2949.255600117267 2444.333822822595 2641.697616182541 2871.072560328403 0.0 4220.121893877476 3244.1824503011603 0.0 1.4700768778925029 0.9854415684452077 0.9090905475564375 0.7534514042499938 0.8142876230457723 0.884991089222457 0.0 1.300827545468572 1.0 11.663639242547392 -6.267266795763274 18.28298956693752 0.7479972692977399 0.8963818442512078 0.0 0.4574426339223018 62.30346835332519 195473.1946970102 0.13462935391716163 0.1580614313191897 5.404222287948332e-07 6.267266795763274 0.1483845749534679 ILEGPQQSLSGSPLQPIPAS(ph)PPPQIPPGLRPR ddPTM_PC-9_AZD4547_30min_R2 2 ILEGPQQSLSGSPLQPIPASPPPQIPPGLRPR 32 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 ILEGPQQSLSGSPLQPIPAS(1)PPPQIPPGLRPR;ILEGPQQSLSGSPLQPIPAS(1)PPPQIPPGLRPR 145.6 2.6543e-15 57157000.0 28967.2 24490.0 40826.6 57388.5 57642.0 37606.3 30876.2 36994.3 34584.0 34547.3 True False 38178.167044810136 32405.913571947927 40285.21260837344 44158.46796848648 49639.403273345415 35254.77211608411 33624.12198487492 31277.680979443234 36412.03963536468 33337.80954237972 1.145191227884281 0.9720468746080289 1.2083941075121338 1.3245761666599996 1.4889821483394932 1.0575011555953462 1.0085882199948148 0.9382044414070574 1.0922145196455375 1.0 15.024871694846698 -6.978748943612337 24.997880864980687 1.0086652875220943 1.2234536376698537 0.40491886391652254 0.1274003959051053 272.66391479134273 320736.9608508518 0.050211301556998426 0.04427861709455054 1.0501493221698003e-07 6.978748943612337 0.21478835014775943 ILEGPQQSLSGSPLQPIPAS(ph)PPPQIPPGLRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ILEGPQQSLSGSPLQPIPASPPPQIPPGLRPR 32 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 ILEGPQQSLSGSPLQPIPAS(1)PPPQIPPGLRPR;ILEGPQQSLSGSPLQPIPAS(1)PPPQIPPGLRPR 98.225 3.2083e-13 35845000.0 19810.0 15374.2 21770.6 22477.9 30899.0 32591.0 26867.1 28893.0 26868.4 22984.9 True False 23163.441734665175 16900.44897145189 22289.693669460277 21218.53613733506 24844.562760327437 30881.8705868235 24322.05378704061 28134.589364663992 27261.299519981145 27151.88042163171 0.8531063548810794 0.6224411977738169 0.820926334505445 0.7814757507708527 0.9150218097061871 1.137375021813227 0.8957778764988742 1.0361930344334223 1.0040298902562292 1.0 14.728764495848688 -6.368929199134808 3.0179658235732725 1.0108814296273116 0.7594227841739347 0.6765691459060462 0.07942811712732623 0.14848696900669225 2.596592276660962 0.025075065989283142 0.029168251754957804 4.2763259528027967e-07 6.368929199134808 -0.2514586454533769 ILEGPQQSLSGSPLQPIPAS(ph)PPPQIPPGLRPR ddPTM_PC-9_Lapatinib_30min_R1 1 ILEGPQQSLSGSPLQPIPASPPPQIPPGLRPR 32 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 ILEGPQQSLSGSPLQPIPAS(1)PPPQIPPGLRPR 77.80199999999999 2.4677e-07 18825000.0 24844.0 21007.0 24433.0 23669.0 24274.0 24446.0 25946.0 26131.0 28092.0 20502.0 True False 24489.720004168375 20958.35958216623 22424.21305410745 25409.697217469395 22846.251044520173 23400.50156640933 27289.356925246975 27345.14165590554 24927.983138125623 24045.743382802204 1.018463834296914 0.8716037282987846 0.932564766125946 1.0567232966331457 0.9501162297548297 0.9731660690991838 1.1348934608012426 1.1372134028288392 1.036690059495287 1.0 14.553493907888418 -7.208821484440537 8.289753210909863 1.088540748733524 0.9642588042616363 0.43944566884641556 0.060328900018883115 0.2997550509260623 44.313073243435234 0.023350881430429182 0.01802345048805266 6.182704863072248e-08 7.208821484440537 -0.12428194447188756 ILEINGT(ph)PIR ddPTM_PC-9_AZD4547_30min_R2 1 ILEINGTPIR 10 0 E9PC47;P53667-4;P53667-2;P53667;P53667-3 E9PC47 LIMK1 LIM domain kinase 1 1 ILEINGT(1)PIR 90.79299999999999 0.020743 3154300.0 7828.4 5172.8 8498.5 11541.0 11294.0 10283.0 7909.3 13060.0 7219.6 9317.0 True False 10317.668359164565 6844.806440382699 8385.80433717874 8880.400756672545 9726.02304863057 9640.002384432744 8613.212377655647 11041.877088944213 7601.213316894477 8990.814665874093 1.1475788059926018 0.7613110374038883 0.932707952373687 0.9877192542272459 1.0817732775147801 1.0722056612981619 0.9580013266593417 1.2281286512172491 0.8454421094615547 1.0 13.134236130231262 -5.955371349332019 3.7396735285440097 1.0406560244862066 0.9296947512237749 0.07288134380177635 0.12664727493717007 0.4528377176321224 13.347168453932007 0.03502187512614788 0.05253941525730382 1.1082268057953927e-06 5.955371349332019 -0.11096127326243177 ILEINGT(ph)PIR ddPTM_PC-9_Lapatinib_30min_R1 1 ILEINGTPIR 10 0 E9PC47;P53667-4;P53667-2;P53667;P53667-3 E9PC47 LIMK1 LIM domain kinase 1 1 ILEINGT(1)PIR 103.44 0.0069188999999999995 1536000.0 7665.2 7602.5 9498.6 7171.2 6987.4 6635.4 5085.1 5547.3 6672.5 3492.5 True False 7555.892842374476 7584.896878346207 8717.661773656326 7698.593970421915 6576.414869756958 6351.619409872875 5348.381596414611 5805.047809414287 5920.972785460034 4096.173971536272 1.8446220533793964 1.8517028161041431 2.128244999903352 1.879459716290945 1.6055018452476693 1.5506224720945379 1.3057017679375316 1.4171878073911741 1.4454886014617614 1.0 12.000061275034819 -6.651856810701215 1.245008664694225 1.316011846374606 1.9478702288066747 0.7984282863117301 0.14102345686657444 0.2019812271426913 0.6591842828129535 0.06637573762574436 0.06630055587472979 2.2291699978305415e-07 6.651856810701215 0.6318583824320687 ILELDQFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ILELDQFK 8 0 P12956;B1AHC9;P12956-2 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 127.56 0.016691 1495300.0 17022.0 16857.0 16999.0 19326.0 17694.0 14947.0 17010.0 17906.0 14625.0 17906.0 False True 19903.488400175185 18530.45155596809 17404.3206290665 18243.226875737368 14226.98771744178 14163.15300731033 15398.689658264597 17435.98647297524 14838.862957218304 21152.216056181987 0.9409646888680562 0.8760524905168197 0.8228131077537798 0.8624735501605075 0.6726003402978561 0.6695824669004825 0.7279941551922711 0.8243101539178618 0.7015275807416627 1.0 14.368521197778039 -5.532465122188467 1.3223081069866685 0.7556372333064678 0.9231004830751655 0.22782902766561097 0.09538349972891484 0.687419577558452 2.1950675300954563 0.030315531766121298 0.1069825411284854 2.9345051620464486e-06 5.532465122188467 0.16746324976869764 ILELDQFK ddPTM_PC-9_Lapatinib_30min_R1 2 ILELDQFK 8 0 P12956;B1AHC9;P12956-2 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 ; 125.31 0.01514 10021900.0 153845.0 138835.0 146967.0 136315.0 142921.0 128383.0 142786.0 133496.0 136723.0 147016.0 False True 151651.14208828218 138513.53608749685 134883.94056902573 146340.0598335093 134514.66777349706 122892.35836539014 150178.7604227362 139698.71151110795 121323.8159829828 172427.51971349397 0.879506602775857 0.8033145539508503 0.7822645758237968 0.8487047779650738 0.7801229641127297 0.7127189358728144 0.8709674689531789 0.8101880241810107 0.7036221142922822 1.0 17.395630523722986 -10.630493908122665 4.285518852281725 1.000028748074489 0.799485628110785 0.536050106295034 0.05608429924993565 39361328.41920579 0.9275855015234433 11670.770822949047 0.013381720585841772 2.341564320216068e-11 10.630493908122665 -0.2005431199637039 ILELT(ph)PEPDRPR ddPTM_PC-9_AZD4547_30min_R2 5 ILELTPEPDRPR 12 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YF61 Q14004 CDK13 Cyclin-dependent kinase 13 1 ILELT(1)PEPDRPR;ILELT(1)PEPDRPR;ILELT(1)PEPDRPR;ILELT(1)PEPDRPR;ILELT(1)PEPDRPR 111.83 0.00073964 107336850.0 41170.899999999994 39475.0 52963.8 74518.5 63066.4 57263.0 47651.4 53357.899999999994 48610.1 51978.6 True False 54262.389792081194 52234.521774301495 52261.46540606786 57339.41112434821 54310.71896530497 53682.33555769448 51892.28228700642 45112.66259756329 51179.530646513995 50158.84503505448 1.0818109897498411 1.0413820680638954 1.0419192341758252 1.1431565277126188 1.0827745121991719 1.0702466438407332 1.0345589546717133 0.8993959602944492 1.0203490652694691 1.0 15.614216508363585 -7.54825464538981 7.406385986084078 0.968862775575806 1.0750460391495815 0.5812398204126504 0.03930960804949146 0.12625178192317804 26.703054081457054 0.0184350859549549 0.010741273164918868 2.8297323164504296e-08 7.54825464538981 0.1061832635737755 ILELT(ph)PEPDRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ILELTPEPDRPR 12 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YF61 Q14004 CDK13 Cyclin-dependent kinase 13 1 ILELT(1)PEPDRPR;ILELT(1)PEPDRPR;ILELT(1)PEPDRPR;ILELT(1)PEPDRPR;ILELT(1)PEPDRPR 128.35 0.00014937 72966900.0 45795.0 47533.7 49772.8 57544.0 64446.0 55435.0 53646.6 50445.0 47773.9 47725.1 True False 53547.18900752102 52252.531596720626 50959.572316395155 54319.99624016514 51818.26892948193 52527.89101225985 48564.805680250254 49120.872200895574 48472.50290816078 56377.28283831628 0.9498008118108201 0.9268366435213812 0.9039025960605709 0.9635085890171188 0.9191338482574782 0.9317208699628883 0.8614250853402898 0.8712883936206844 0.8597878519114601 1.0 15.782826326947852 -7.23563165118925 22.608620660434507 0.8873993719596525 0.9317314624373346 0.1244654500500465 0.040827585782367885 341.8888044519028 299508.19040392176 0.014659247635634148 0.011348266704107738 5.812572044144026e-08 7.23563165118925 0.04433209047768216 ILELT(ph)PEPDRPR ddPTM_PC-9_Lapatinib_30min_R1 5 ILELTPEPDRPR 12 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YF61 Q14004 CDK13 Cyclin-dependent kinase 13 1 ILELT(1)PEPDRPR;ILELT(1)PEPDRPR;ILELT(1)PEPDRPR;ILELT(1)PEPDRPR;ILELT(1)PEPDRPR 116.9 0.00047244 101263370.0 114218.9 116533.5 111751.0 101287.0 111785.9 113387.2 113349.0 99897.2 107711.8 97861.94 True False 112590.11754081919 116263.673840547 102563.26415133449 108735.98386352704 105210.87314153537 108537.89377447305 119217.65659908362 104538.78860465824 95580.16282846229 114777.24593616149 0.9809445820249184 1.012950545138644 0.8935853384074022 0.9473653334041962 0.9166527065830897 0.9456394679032573 1.0386872034322192 0.9107971510555514 0.8327448707178727 1.0 16.808477137105783 -5.244893291420107 24.77131529722537 0.9362699299900619 0.9969475698121748 0.1722383592501654 0.05370942123589448 1331.5462554440348 1993463.2498589305 0.01392348461317891 0.03659937223470191 5.689927183587794e-06 5.244893291420107 0.06067763982211294 ILENSEDSS(ph)PECLF ddPTM_PC-9_AZD4547_30min_R2 1 ILENSEDSSPECLF 14 0 A0A0B4J1V9;Q9NRZ9-6;Q9NRZ9-5;Q9NRZ9-3;Q9NRZ9-2;Q9NRZ9;A0A087WSW7;F6XU50 A0A0B4J1V9 HELLS Lymphoid-specific helicase 1 ILENS(0.001)EDS(0.109)S(0.891)PECLF 138.31 2.5166999999999998e-05 0.0 606.66 736.59 522.26 2100.4 1149.9 2246.5 888.09 922.92 620.14 0.0 True False 799.5652606881062 974.6783126974734 515.3344911613777 1616.1852308565135 990.2562337188143 2106.025999866591 967.1282895417044 780.3039205917601 652.9193343590977 0.0 0.0 ILEQQNS(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 1 ILEQQNSSR 9 0 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181;Q5JXL7 G3V1Q4 SEPT7;DKFZp586I031 Septin-7 1 ILEQQNS(0.5)S(0.5)R 94.538 0.0057152 4585800.0 18978.0 14071.0 21188.0 18823.0 14960.0 11954.0 9792.2 13163.0 18441.0 18944.0 True False 18707.370239861044 14038.419464019662 19446.004428045217 20207.306211687268 14080.082212491634 11442.755286135027 10299.192202397418 13774.601033894021 16363.98038766108 22218.445158706687 0.8419747694419667 0.6318362677380447 0.8752189583538413 0.909483362465113 0.6337114101332202 0.5150115232816362 0.46354243642298704 0.619962420209958 0.7365042995030896 1.0 14.439470240366942 -4.745667595366566 23.962781558960955 0.6928981995753833 0.8419754721555747 0.04652069418989635 0.16527613664885504 1746.403909524262 2653138.6113165086 0.04371910579151212 1.009852284323874 1.7961078237514008e-05 4.745667595366566 0.14907727258019132 ILEQQNSS(ph)RTLEK ddPTM_PC-9_AZD4547_30min_R2 1 ILEQQNSSRTLEK 13 1 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181;Q5JXL7 G3V1Q4 SEPT7;DKFZp586I031 Septin-7 1 ILEQQNS(0.018)S(0.73)RT(0.252)LEK 59.79600000000001 0.028301999999999997 285100000.0 46173.0 41360.0 53116.0 88453.0 75689.0 66138.0 36828.0 48375.0 60063.0 61872.0 True False 60855.05354193776 54728.81116111747 52411.647134622144 68061.5274352271 65180.888837240884 62002.38040470811 40105.62065471054 40899.755296912415 63237.8075589552 59705.88011237113 1.0192472404293145 0.9166402213335365 0.8778305760836174 1.139946807703529 1.0916996569611797 1.0384635531377275 0.6717197800154462 0.6850205577731352 1.0591554372858538 1.0 15.865585401344573 -7.230429593673412 24.512341080821944 0.8277256103541865 1.0126182725472157 0.24738016464605495 0.13360339031819723 682.9251899274124 539833.210247951 0.05250168116439423 0.04066258386023606 5.882614733384712e-08 7.230429593673412 0.18489266219302924 ILEQQNSS(ph)RTLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ILEQQNSSRTLEK 13 1 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181;Q5JXL7 G3V1Q4 SEPT7;DKFZp586I031 Septin-7 1 ILEQQNS(0.109)S(0.575)RT(0.317)LEK 57.803999999999995 0.03205 120390000.0 52428.0 35852.0 62241.0 74625.0 71929.0 62530.0 60976.0 51676.0 56364.0 58674.0 True False 61303.02489979937 39411.1496223864 63725.061490306995 70444.00318751443 57835.02879664692 59250.81672222616 55199.91185198951 50319.559755247894 57188.21686978823 69311.13173687148 0.8844614618691613 0.5686121209505635 0.9194058716603979 1.0163447259084402 0.8344262652672917 0.8548528243221063 0.7964075967125608 0.7259953559303861 0.825094258839894 1.0 16.08079945502702 -5.294670985347772 24.998143396745935 0.8623431254384352 0.7265365524153182 0.21419844605787952 0.10998347263722227 900.2007022148152 677165.420312115 0.029229695442134714 0.06085209754231661 5.073749419681901e-06 5.294670985347772 -0.13580657302311694 ILEQQNSS(ph)RTLEK ddPTM_PC-9_Lapatinib_30min_R1 1 ILEQQNSSRTLEK 13 1 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181;Q5JXL7 G3V1Q4 SEPT7;DKFZp586I031 Septin-7 1 ILEQQNS(0.015)S(0.611)RT(0.374)LEK 61.423 0.025240000000000002 136430000.0 112140.0 61760.0 79869.0 80328.0 68554.0 63044.0 42307.0 44027.0 67505.0 43278.0 True False 110540.86303604246 61616.99851452311 73302.47912325572 86235.58908635257 64521.78850234973 60347.755082741955 44497.44945025915 46072.65514846552 59901.87604083622 50758.544635689825 2.177778417987145 1.2139236646118965 1.4441406791579794 1.6989373849327782 1.2711512704992445 1.1889181519264773 0.8766494344869707 0.9076827454203736 1.1801338369878607 1.0 15.631363083933875 -6.627158332054855 1.7085796876691743 0.9886110486831133 1.5962498000700391 0.5726388806916464 0.2453306877967006 0.27671790968219917 1.6602792913292104 0.09717461449923294 0.09817907059746733 2.3596178233312634e-07 6.627158332054855 0.6076387513869258 ILEQQNSSRT(ph)LEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ILEQQNSSRTLEK 13 1 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181;Q5JXL7 G3V1Q4 SEPT7;DKFZp586I031 Septin-7 1 ILEQQNS(0.002)S(0.004)RT(0.993)LEK 187.08 0.00037495 40658000.0 34576.0 28868.0 37352.0 54803.0 49664.0 46856.0 47130.0 36669.0 38416.0 33355.0 True False 40429.03389287143 31733.824258034452 38242.61333824882 51732.56558372322 39932.69571600702 44398.78887472622 42665.505208348644 35706.477604017055 38977.76132406826 39401.997461965286 1.026065593042524 0.8053861809586452 0.9705754987463359 1.312942716512294 1.0134688160049252 1.1268156878996891 1.08282594681992 0.9062098346279142 0.9892331311805566 1.0 15.265981147693706 -5.530384288206224 24.94725494702311 1.0656664124258375 0.9087895691990616 0.21963206210579045 0.11310627481303695 226.8278743290474 753938.1697005397 0.03125244591775013 0.0542657156123458 2.94859898561854e-06 5.530384288206224 -0.15687684322677586 ILEQQNSSRT(ph)LEK ddPTM_PC-9_Lapatinib_30min_R1 1 ILEQQNSSRTLEK 13 1 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181;Q5JXL7 G3V1Q4 SEPT7;DKFZp586I031 Septin-7 1 ILEQQNS(0.057)S(0.078)RT(0.865)LEK 158.65 0.0025906999999999996 51610000.0 51483.0 28931.0 47503.0 40397.0 36459.0 31481.0 22357.0 22719.0 36177.0 19628.0 True False 50748.84297917408 28864.012047015338 43597.48670688274 43367.93014044151 34314.55330115192 30134.631015795298 23514.53606635884 23774.607679787132 32102.36529930127 23020.673647333984 2.2044899187844265 1.2538300350892673 1.8938406136491035 1.8838688565251405 1.4905972703855206 1.3090247260981078 1.0214529959718208 1.0327503027931793 1.394501559385037 1.0 14.49064243080622 -6.683721953549532 2.08325929839551 1.1211992325138684 1.7730074127078634 0.6137906728260962 0.24685255560350516 0.22043998623183053 1.9635635435564862 0.09239783025727698 0.08954265775495268 2.071467130657482e-07 6.683721953549532 0.651808180193995 ILESITVSSLMAT(ph)PQDPK ddPTM_PC-9_AZD4547_30min_R2 2 ILESITVSSLMATPQDPK 18 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 ILESIT(0.008)VS(0.003)SLMAT(0.988)PQDPK;ILES(0.002)IT(0.2)VS(0.025)S(0.086)LMAT(0.687)PQDPK 199.05 3.0423e-54 3996600.0 29513.6 30248.6 37430.9 42389.2 43542.7 46580.7 34818.7 44658.1 38042.4 46511.1 True False 38898.3108789841 40025.86840638727 36934.54180908443 32617.024846611526 37497.54770671206 43668.00146538425 37917.4968472404 37757.216786047444 40053.24359890114 44882.76054587703 0.8666648487279229 0.8917871342934606 0.822911544652689 0.7267161032412869 0.8354554677710576 0.9729348403324901 0.8448120477902186 0.841240964834456 0.8923970609597558 1.0 15.4538737922022 -6.5539200618281175 24.925840072322565 0.8971443789631364 0.8250692872916974 0.2934796957727712 0.0617003573288443 298.37629344102754 239590.94667517397 0.021242595593282357 0.021242767432898678 2.793057896572058e-07 6.5539200618281175 -0.072075091671439 ILEVHIDK ddPTM_PC-9_Lapatinib_30min_R1 1 ILEVHIDK 8 0 P31689;P31689-2 P31689 DNAJA1 DnaJ homolog subfamily A member 1 0 98.03299999999999 0.0047256 2226500.0 37375.0 40347.0 42782.0 36101.0 39831.0 35934.0 37153.0 35071.0 38327.0 38223.0 False True 36842.02564626442 40253.57900041231 39264.62910329575 38755.98796940566 37488.21889075897 34397.18658624528 39076.600548974835 36700.52669298008 34010.209658797576 44829.79462105395 0.8218200854518717 0.897920218923054 0.875860115693134 0.8645140647422065 0.8362344554028569 0.7672840546561621 0.8716658391877358 0.8186637258370122 0.7586519176874603 1.0 15.452170269527707 ILEVHVDK ddPTM_PC-9_AZD4547_30min_R2 1 ILEVHVDK 8 0 O60884 O60884 DNAJA2 DnaJ homolog subfamily A member 2 0 76.827 0.019631 0.0 36914.0 39916.0 52018.0 63074.0 62564.0 51378.0 47274.0 58592.0 44640.0 50457.0 False True 48651.88414110175 52818.06640007648 51328.2073320426 48533.263783585826 53878.06853324973 48165.32553801277 51481.29441812711 49537.95271021586 46999.5792656338 48690.515787915494 0.9992065878500442 1.0847711416765358 1.0541725940143307 0.9967703771096896 1.1065413389320007 0.989213705350949 1.0573166783109793 1.0174045583331177 0.9652717475894687 1.0 15.571353162981023 -8.031491715047775 4.678968166415911 0.9838257417939914 1.0420196999506468 0.2832955400964786 0.036967031231060044 0.24497028783359012 12.962654821604099 0.02362172124169689 0.009071858063798873 9.300542570507436e-09 8.031491715047775 0.0581939581566554 ILEVHVDK ddPTM_PC-9_Lapatinib_30min_R1 1 ILEVHVDK 8 0 O60884 O60884 DNAJA2 DnaJ homolog subfamily A member 2 0 80.755 0.015819999999999997 1953500.0 61746.0 55669.0 56353.0 53037.0 59676.0 57895.0 49660.0 48743.0 48733.0 47543.0 False True 60865.49071717039 55540.101850793195 51719.873868870665 56937.51790624543 56165.975007530156 55418.965809836685 52231.151811753865 51007.777725069995 43244.17635875966 55760.74420293458 1.0915473167943688 0.9960430522351283 0.9275319870309183 1.0211039813067797 1.0072673134189312 0.993870627123375 0.9367011247494262 0.9147614231874897 0.7755308322532002 1.0 15.76696219561085 -7.506195863858388 2.0038208203706276 0.8817866141912869 1.0039298961833711 0.38246365796164594 0.06314960591301741 0.3380659341207556 2.6751138737096785 0.03646390275350693 0.018944132119710994 3.117483303233536e-08 7.506195863858388 0.12214328199208424 ILGETS(ph)LMR ddPTM_PC-9_AZD4547_30min_R2 1 ILGETSLMR 9 0 H0Y820;O96017-13;O96017-4;O96017-12;O96017;O96017-9 H0Y820 CHEK2 Serine/threonine-protein kinase Chk2 1 ILGET(0.231)S(0.769)LMR 65.157 0.045696 4494600.0 40591.0 42394.0 59179.0 83064.0 74618.0 76928.0 58267.0 74389.0 67039.0 69460.0 True False 53498.093654750504 56097.03144014536 58394.24779312829 63914.87812600712 64258.5787004352 72117.67999899256 63452.65012186428 62893.88933916312 70582.54467716902 67028.22654197848 0.7981427588755564 0.8369165400044244 0.8711889125778541 0.9535516814841948 0.9586793805471088 1.0759300032177737 0.9466556612851023 0.9383194600825951 1.0530271844946477 1.0 16.032481142531218 -5.6613188809249 1.3356452982994327 0.995566890155434 0.8041057319071001 0.7620438945567058 0.04104875480562806 0.2375892183972175 0.8211294270332529 0.013935476020350631 0.03966016711727363 2.181127829628976e-06 5.6613188809249 -0.19146115824833387 ILGPGLNK ddPTM_PC-9_Lapatinib_30min_R1 1 ILGPGLNK 8 0 P62906 P62906 RPL10A 60S ribosomal protein L10a 0 125.86 0.016002000000000002 5177900.0 67078.0 59054.0 62198.0 65941.0 73312.0 65914.0 75228.0 45522.0 60400.0 60436.0 False True 66121.45541940145 58917.264091266974 57084.32053122313 70790.52111272745 68999.9322969377 63095.01187303872 79122.937746569 47637.11830623136 53597.115959803086 70882.28207409185 0.9328347435299275 0.8311987476599852 0.8053397670175745 0.9987054457238201 0.9734440014898705 0.8901379869102796 1.116258329040018 0.6720596023761934 0.75614264088985 1.0 16.11313743214407 -11.573862946945912 2.3842046828197674 1.1472411486241296 0.8886914028551404 0.07274830730435888 0.12156271695246429 23914975.192325246 8454277.796674112 19187838.333023157 0.033457762051683285 2.6677003947709837e-12 11.573862946945912 -0.25854974576898926 ILGPQGNTIK ddPTM_PC-9_Lapatinib_30min_R1 2 ILGPQGNTIK 10 0 Q07666;Q07666-2 Q07666 KHDRBS1 KH domain-containing, RNA-binding, signal transduction-associated protein 1 0 ; 99.815 0.017664 0.0 53685.0 50790.0 42826.0 38762.0 45583.0 40241.0 39545.0 36360.0 40267.0 44015.0 False True 52919.44205537676 50672.39887552828 39305.011593140654 41612.68678624141 42901.8975596261 38519.98623635269 41592.44660482894 38049.418338705946 35731.706429691905 51622.9341036991 1.0251149605148995 0.9815869584967525 0.7613866254518882 0.8060891444614653 0.8310627496191061 0.7461797146007727 0.8056970671461424 0.7370642331618161 0.6921672905673044 1.0 15.655724522076982 -5.202291908578013 4.870383007515795 0.7879267418760169 1.0117654769477193 0.5197641573480938 0.07893246507059652 0.1474782660726709 7.301490516193756 0.019106311383976185 0.05311436360738606 6.276363547817939e-06 5.202291908578013 0.2238387350717025 ILGQS(ph)SPEKK ddPTM_PC-9_Lapatinib_30min_R1 1 ILGQSSPEKK 10 1 P29374;P29374-3;P29374-2;H7C485 P29374 ARID4A AT-rich interactive domain-containing protein 4A 1 ILGQS(0.886)S(0.114)PEKK 142.76 0.00018730000000000003 14826000.0 93782.0 79831.0 69840.0 75524.0 76625.0 80804.0 72184.0 77759.0 66581.0 69759.0 True False 92444.65148248743 79646.1562243019 64098.02479019615 81078.28690067853 72118.06815054623 77348.201283324 75921.33432097544 81371.96701318576 59081.94665098759 81816.75020197548 1.1298988441153623 0.9734700538420901 0.7834340111525048 0.9909741794990152 0.8814584785207581 0.9453834464505095 0.9279436562018606 0.9945636659034768 0.7221253167002599 1.0 16.32010861341918 -4.837040127513407 3.757976482353084 0.9083310935971977 1.1404803606187828 0.3756720340434604 0.08716103233288695 0.2343777099617506 5.600457160089575 0.020529337386301277 0.13477590441100185 1.4553246067212321e-05 4.837040127513407 0.23214926702158512 ILGQSS(ph)PEKK ddPTM_PC-9_AZD4547_30min_R2 2 ILGQSSPEKK 10 1 P29374;P29374-3;P29374-2;H7C485 P29374 ARID4A AT-rich interactive domain-containing protein 4A 1 ILGQS(0.083)S(0.917)PEKK;ILGQS(0.225)S(0.775)PEKK 158.34 0.00062281 21399800.0 164982.0 141967.0 147215.0 180452.0 173141.0 177408.0 152558.0 158285.0 150877.0 169850.0 True False 217442.8441612188 187855.05643400276 145262.83291142786 138851.5793556081 149103.36078120617 166314.64971481496 166135.36645599347 133825.69027745258 158852.05019849975 163903.6031983168 1.326650786914804 1.1461313404239544 0.8862699176641385 0.8471539163638961 0.9097015432955252 1.0147101495601711 1.0136163160182412 0.8164902275853501 0.96917973185919 1.0 17.322488044915694 -5.019923273766496 2.9178661452547234 0.9280100713008297 1.3223082394324692 0.785086201163492 0.06670538584124132 0.12586185560096025 2.0054715080390966 0.018441687685823015 0.08981971288987274 9.551613182068655e-06 5.019923273766496 0.39429816813163954 ILGQSS(ph)PEKK ddPTM_PC-9_Lapatinib_30min_R1 1 ILGQSSPEKK 10 1 P29374;P29374-3;P29374-2;H7C485 P29374 ARID4A AT-rich interactive domain-containing protein 4A 1 ILGQS(0.204)S(0.796)PEKK 115.14 0.0016884 13821000.0 73375.0 57255.0 55005.0 57163.0 54128.0 53236.0 52511.0 55307.0 51627.0 43967.0 True False 72328.65904467306 57122.429565236715 50482.70122544019 61366.95771017793 50944.297459742476 50959.22037917721 55229.76264170369 57876.76512813009 45812.223603588616 51566.637367655036 1.4026250835203948 1.1077400521187857 0.9789798948012317 1.190051569053252 0.9879313459305974 0.9882207369050047 1.0710367295802448 1.1223684165303565 0.8884082023219949 1.0 15.654150350795737 -4.774917518278254 3.275375129115503 1.0370409946482977 1.4565214416938883 0.6624968100961182 0.07979630758133287 0.19758867014974113 3.2620356021744126 0.019544257159634714 0.21479197081293408 1.6791228888467938e-05 4.774917518278254 0.4194804470455906 ILGSAS(ph)PEEEQEKPILDRPTR ddPTM_PC-9_AZD4547_30min_R2 2 ILGSASPEEEQEKPILDRPTR 21 2 Q7Z422-4;Q7Z422-5;Q7Z422;Q7Z422-2;Q7Z422-3 Q7Z422-4 SZRD1 SUZ domain-containing protein 1 1 ILGS(0.246)AS(0.753)PEEEQEKPILDRPT(0.001)R;ILGS(0.018)AS(0.982)PEEEQEKPILDRPTR 77.027 0.00355 116837000.0 110020.0 102328.0 125587.0 177169.0 152221.0 168204.0 113561.0 151701.0 142013.0 132360.0 True False 145004.07144183828 135403.5248668963 123921.63432291205 136325.42428376386 131087.74167572116 157686.17728981117 123667.70900319271 128259.09619218449 149519.51725471445 127726.11668724843 1.135273467969725 1.0601083660786998 0.9702137474855509 1.0673261492602315 1.0263190103610842 1.2345648750593683 0.9682257020778829 1.0041728310447355 1.1706260327387044 1.0 16.962694023461665 -4.766183331889554 6.335467756457986 1.0553091948117512 1.1375304058020685 0.07863334463618254 0.08180413024568689 0.3339016385542943 59.17863749626451 0.020008423758459886 0.11871012922828797 1.7132339349315332e-05 4.766183331889554 0.08222121099031732 ILGSAS(ph)PEEEQEKPILDRPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ILGSASPEEEQEKPILDRPTR 21 2 Q7Z422-4;Q7Z422-5;Q7Z422;Q7Z422-2;Q7Z422-3 Q7Z422-4 SZRD1 SUZ domain-containing protein 1 1 ILGS(0.088)AS(0.91)PEEEQEKPILDRPT(0.002)R;ILGS(0.254)AS(0.746)PEEEQEKPILDRPTR;ILGS(0.258)AS(0.741)PEEEQEKPILDRPT(0.001)R 64.331 0.0036122 113390000.0 76213.0 83849.0 96935.0 109500.0 98881.0 98970.0 112802.0 95264.0 86599.0 73627.0 True False 89114.35562463592 92172.97458126419 99246.29802803486 103365.0700037896 79505.97787319771 93779.83897327252 102116.57794424238 92763.4209405513 87865.34654578783 86974.99226898886 1.0245974538178815 1.0597641020329092 1.1410900471378524 1.188445865957779 0.9141245753412474 1.0782391182426116 1.1740912563513073 1.0665527931714034 1.0102368997521192 1.0 16.40831302515671 ILGSAS(ph)PEEEQEKPILDRPTR ddPTM_PC-9_Lapatinib_30min_R1 4 ILGSASPEEEQEKPILDRPTR 21 2 Q7Z422-4;Q7Z422-5;Q7Z422;Q7Z422-2;Q7Z422-3 Q7Z422-4 SZRD1 SUZ domain-containing protein 1 1 ILGS(0.253)AS(0.744)PEEEQEKPILDRPT(0.003)R;ILGS(0.218)AS(0.781)PEEEQEKPILDRPT(0.001)R;ILGS(0.07)AS(0.93)PEEEQEKPILDRPTR;ILGS(0.073)AS(0.921)PEEEQEKPILDRPT(0.006)R 77.027 0.00050548 190325000.0 230833.0 203820.0 186134.0 191649.0 229515.0 215531.0 187047.0 206178.0 239828.0 203722.0 True False 227541.27909041248 203348.06731266377 170830.78101801794 205743.50678232228 216015.37894385122 206313.2415573007 196731.3784319998 215757.78256979404 212816.04513919947 238935.07625749827 0.9523142547944414 0.8510599217902913 0.7149673614011995 0.8610854044744535 0.9040756272681091 0.8634698797214634 0.823367508502536 0.9029975253079784 0.890685656005774 1.0 17.866259134962505 -8.947626455687606 0.662086919818218 1.002779245473985 0.8476759294113551 0.35192925300019406 0.05840433650541485 1.7370204501423478 1.3770504328862077 0.07013427207375664 0.02416774195889192 1.1281673955782792e-09 8.947626455687606 -0.15510331606262995 ILIPS(ph)DIESSK ddPTM_PC-9_AZD4547_30min_R2 1 ILIPSDIESSK 11 0 P30414;A0A087WYW3 P30414 NKTR NK-tumor recognition protein;Putative peptidyl-prolyl cis-trans isomerase 1 ILIPS(0.984)DIES(0.014)S(0.002)K 102.73 0.0079691 0.0 14206.0 15546.0 17127.0 20642.0 19987.0 22061.0 18834.0 17720.0 17097.0 19549.0 True False 18723.212496843775 20570.940481400663 16899.884789416996 15883.305815720885 17212.15005073305 20681.522182531433 20510.189513707457 14981.781165091235 18000.712515782714 18864.59546025249 0.992505380584142 1.0904522455699315 0.8958519585020988 0.841963764830624 0.9124049379695882 1.0963141100007783 1.087231876078245 0.7941745263850314 0.9542061240438487 1.0 14.203393542313677 -5.261136081148849 24.9992111519266 0.9456618256407326 1.0414788113378093 0.13758589355488626 0.0937279920719271 54.85489300715717 4520925.293975314 0.026131071515211296 0.06112474676957918 5.481051955926946e-06 5.261136081148849 0.09581698569707664 ILIPS(ph)DIESSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ILIPSDIESSK 11 0 P30414;A0A087WYW3 P30414 NKTR NK-tumor recognition protein;Putative peptidyl-prolyl cis-trans isomerase 1 ILIPS(0.997)DIES(0.003)SK;ILIPS(0.993)DIES(0.005)S(0.002)K 98.902 0.0047841 5079700.0 34770.0 34521.0 35623.0 40541.0 50048.0 38144.0 38640.0 37664.0 36682.0 28361.0 True False 40655.87426119674 37948.01673865896 36472.38742097984 38269.61920569538 40241.453672574135 36143.6614913257 34979.73947062575 36675.359908306695 37218.40485447394 33502.62479444751 1.2135131056338833 1.1326878706216534 1.0886426853046007 1.1422871921377908 1.201143310993456 1.07883073977284 1.0440895209029426 1.0947010908346801 1.110910117724336 1.0 15.031986508838951 -6.88347839984511 7.864977216493925 1.0691492500582647 1.1497490880416905 0.5189544215155557 0.04313641415020072 0.22781721477776512 14.752020374888941 0.015542902154474013 0.013712389356678975 1.3077405793427885e-07 6.88347839984511 0.08059983798342585 ILIPS(ph)DIESSK ddPTM_PC-9_Lapatinib_30min_R1 1 ILIPSDIESSK 11 0 P30414;A0A087WYW3 P30414 NKTR NK-tumor recognition protein;Putative peptidyl-prolyl cis-trans isomerase 1 ILIPS(0.999)DIES(0.001)SK 111.79 0.0017679000000000002 1496500.0 12581.0 10087.0 12388.0 11287.0 12324.0 10120.0 11198.0 10866.0 11086.0 9360.9 True False 12401.592632927164 10063.644171243435 11369.506459062863 12117.083632328226 11599.126549916235 9687.191190872218 11777.777647765188 11370.874028283246 9837.377939244654 10978.919092384793 1.1295822957224604 0.9166334214288717 1.035576122147488 1.103668178111713 1.0564907576340217 0.882344710745838 1.0727629513122563 1.03570068534072 0.8960242676410708 1.0 13.422448403216933 ILIVT(ph)QTPHYMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ILIVTQTPHYMR 12 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50 Q6PKG0 LARP1 La-related protein 1 1 ILIVT(0.581)QT(0.418)PHY(0.001)MR 94.67299999999999 0.0048311000000000005 2709800.0 14846.0 13571.0 13312.0 15405.0 15956.0 15897.0 15076.0 15903.0 14574.0 14568.0 True False 17359.13457813422 14918.239192385525 13629.40856604114 14541.907793683868 12829.536341104389 15063.333334930909 13647.892139212052 15485.563100621324 14787.117178700813 17209.063079775442 1.0087204920839152 0.8668827072821788 0.7919901567482074 0.8450144976674479 0.7455104488623793 0.8753139706155035 0.7930642171479646 0.8998492845796108 0.8592633492103957 1.0 14.070880933815635 -9.073184875415777 1.0741748133930926 1.000026416442432 0.8449716884980595 0.2914929945903624 0.06801534166663743 2.830587995714441 4.363910058471243 0.06691689394365796 0.020614730114039248 8.449190938221816e-10 9.073184875415777 -0.15505472794437247 ILIVTQT(ph)PHYMR ddPTM_PC-9_AZD4547_30min_R2 4 ILIVTQTPHYMR 12 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50 Q6PKG0 LARP1 La-related protein 1 1 ILIVT(0.003)QT(0.996)PHYMR;ILIVT(0.061)QT(0.939)PHYMR;ILIVT(0.006)QT(0.994)PHYMR;ILIVT(0.099)QT(0.901)PHYMR 112.02 0.0010023999999999999 97117400.0 309380.0 312093.0 309658.0 398350.0 368345.0 388357.0 375258.0 381347.0 367613.0 365664.0 True False 407756.4044962365 412970.9589387482 305551.73259305744 306516.56194614945 317206.6548475143 364072.9753973683 408655.2350289281 322418.58363228315 387044.2726831863 352862.21465945913 1.155568342418739 1.1703462195216876 0.8659236378934475 0.8686579327910272 0.8989533071815146 1.031770930046246 1.1581155988133038 0.9137237432561132 1.0968708368412743 1.0 18.42874542554626 -5.238627802724678 24.249536649175074 0.9776167679987839 1.1629573730529823 0.38848489670771724 0.09217477288503655 591.7928987428915 629093.5750570418 0.02516250482000051 0.06645583073335541 5.772609732918569e-06 5.238627802724678 0.18534060505419836 ILIVTQT(ph)PHYMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ILIVTQTPHYMR 12 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50 Q6PKG0 LARP1 La-related protein 1 1 ILIVT(0.003)QT(0.997)PHYMR;ILIVT(0.011)QT(0.989)PHYMR;ILIVT(0.011)QT(0.989)PHYMR 99.834 0.0032191000000000003 129238100.0 73819.0 65103.0 73753.0 85765.0 78534.0 80590.0 79408.0 78784.0 77311.0 63129.0 True False 86315.09870829123 71565.99558926198 75511.55122981008 80959.86510388179 63145.826461036064 76363.71852941324 71885.89937586564 76716.00347854788 78441.52711695754 74573.78797111097 1.1574455456349986 0.9596668955181118 1.0125749715042287 1.0856343402489452 0.846756322549929 1.0240021407923607 0.963956657313873 1.0287261189986323 1.0518645927888883 1.0 16.186381004543364 -4.753402468979762 24.994813487224352 0.9962873947706898 1.157445840442494 0.3791710286375116 0.06157681006906958 317.46932235791934 987252.6582612885 0.015018626898738225 0.16187227084508488 1.764401957863469e-05 4.753402468979762 0.16115844567180426 ILIVTQT(ph)PHYMR ddPTM_PC-9_Lapatinib_30min_R1 6 ILIVTQTPHYMR 12 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50 Q6PKG0 LARP1 La-related protein 1 1 ILIVT(0.002)QT(0.997)PHY(0.002)MR;ILIVT(0.001)QT(0.998)PHYMR;ILIVT(0.045)QT(0.954)PHY(0.001)MR;ILIVT(0.006)QT(0.984)PHY(0.01)MR;ILIVT(0.028)QT(0.972)PHYMR;ILIVT(0.001)QT(0.999)PHYMR 145.52 0.00019286 85760900.0 289216.0 235940.0 265373.0 203585.0 226667.0 233874.0 216352.0 184191.0 239176.0 165946.0 True False 285091.726804281 235393.69542611003 243555.0563094038 218557.32003965112 213334.8927044679 223871.75420692182 227553.64794153356 192749.1862823047 212237.48024506395 194629.5449908542 1.4647916215273364 1.2094448221474874 1.2513776175187001 1.122940096530161 1.0961074420355486 1.1502454790070118 1.1691629241193906 0.9903387807404171 1.0904689740452158 1.0 17.570371203961834 -1.5228787452803376 0.40785736344965884 1.0600969423566695 7.380823116871623 0.7957007870096489 0.05862757149577151 33.582427571365265 0.43974314314597884 0.04108664686253712 171.61340410779178 0.029999999999999995 1.5228787452803376 6.320726174514953 ILIVTQT(ph)PPYVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ILIVTQTPPYVK 12 0 A0A3B3ISF0;Q659C4;H0Y9K3;D6R9W6;Q659C4-9;Q659C4-2;D6RJB0;Q659C4-4 A0A3B3ISF0 LARP1B La-related protein 1B 1 ILIVT(0.176)QT(0.822)PPY(0.001)VK 116.98 0.0015937000000000002 1740000.0 16180.0 14617.0 16478.0 18299.0 21757.0 15465.0 17861.0 15027.0 14906.0 12275.0 True False 18918.954430433223 16068.079159612344 16870.898013162998 17273.76635615844 17493.872033931333 14653.988175423443 16169.076777558135 14632.557172422585 15123.972050618526 14500.360331153463 1.3047230550393 1.1081158531688828 1.1634812948004145 1.1912646280276513 1.2064439527303625 1.0105947604584637 1.115081033042986 1.0091167969795276 1.043006636057537 1.0 13.823801130928215 -6.758568855406884 24.999999804651885 1.0410997101239943 1.188052689833984 0.676940693584908 0.0548395049903368 47.52507434340506 413906.72386375023 0.017968951751402083 0.017224322768099997 1.7435369057368574e-07 6.758568855406884 0.14695297970998977 ILKS(ph)PEIQR ddPTM_PC-9_AZD4547_30min_R2 1 ILKSPEIQR 9 1 P36578;H3BM89 P36578 RPL4 60S ribosomal protein L4 1 ILKS(1)PEIQR 56.434 0.040935 131440000.0 394680.0 394470.0 464330.0 622850.0 488530.0 439180.0 408930.0 476490.0 413060.0 466540.0 True False 520180.03014601447 521974.7132187131 458172.680812168 479261.5554365736 420706.0421416226 411718.00517311797 445323.97779762006 402859.4191509214 434893.5083212969 450206.5766037247 1.155425214065411 1.1594115686989603 1.0176943310525095 1.0645369933332256 0.9344733373629308 0.9145090866487171 0.9891547590376444 0.894832372707699 0.9659865735459781 1.0 18.780227606227278 -5.525183688910549 1.0070653902092348 0.9443943212280517 1.186826262696566 0.7785978057541787 0.04130588469948116 0.3246176142567581 0.543703631192479 0.014744281605883737 0.06592805286511247 2.984120190431167e-06 5.525183688910549 0.24243194146851432 ILKS(ph)PEIQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ILKSPEIQR 9 1 P36578;H3BM89 P36578 RPL4 60S ribosomal protein L4 1 ILKS(1)PEIQR 92.943 0.032039 13103000.0 34368.0 35979.0 31923.0 35161.0 39702.0 36663.0 29978.0 34848.0 33267.0 27317.0 True False 40185.82360105867 39550.75734307263 32684.16538865166 33191.043163500064 31922.67810319169 34740.3277384772 27138.26681807501 33933.27692450805 33753.46694001921 32269.355858746992 1.2453246286341915 1.225644463316795 1.0128545959119983 1.0285623087361144 0.9892567500549804 1.076573325186484 0.8409918976030276 1.0515635041816316 1.045991345094356 1.0 14.977877159460876 -5.2554296208060265 4.533744369368533 1.003399830685535 1.2411947279169822 0.6973914630181353 0.0606139656320947 0.09926967477607321 5.585499640559591 0.01575907106564445 0.040328032922925916 5.553546073092997e-06 5.2554296208060265 0.2377948972314472 ILLAELEQLK ddPTM_PC-9_Lapatinib_30min_R1 2 ILLAELEQLK 10 0 P08670;B0YJC4;A0A1B0GTT5 P08670 VIM Vimentin 0 ; 180.8 0.0072803 16300100.0 115958.0 109288.0 113625.0 111569.0 109905.0 94522.0 112138.0 108133.0 103268.0 115289.0 False True 114304.4176559074 109034.95035063464 104283.19110518371 119774.15644327378 103440.60398154377 90479.51440154386 117943.95694455209 113157.25393892446 91636.87037975073 135216.55003706395 0.8453433963858391 0.8063728169425065 0.771230970444068 0.885795092467917 0.7649995799566685 0.6691452664392242 0.8722597708063303 0.8368594961778506 0.677704543967675 1.0 17.044912217736858 -10.763494475664906 4.513249509379202 1.0000770174607514 0.7939939939401393 0.4389032372061781 0.07046253856485582 5.428131711403313e-05 9.133169612536586e-06 0.0678196823927366 0.016442552583421453 1.7238740189988058e-11 10.763494475664906 -0.20608302352061214 ILLDQGQTHSVETPYGSVTFTVYGTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ILLDQGQTHSVETPYGSVTFTVYGTPK 27 0 Q9UN36-3;Q9UN36;G3V5B5;G3V5P9;G3V2S0;G3V552;G3V3P6;G3V4T9;G3V2T2;G3V3P1;G3V3D5;G3V3L1;G3V358;G3V383;G3V5S0;G3V2I9 Q9UN36-3 NDRG2 Protein NDRG2 0 33.075 0.046395 8257700.0 32019.0 41382.0 14039.0 23137.0 23909.0 15481.0 30812.0 20365.0 22802.0 23370.0 False True 37439.184295923485 45490.1314758896 14373.74300320399 21840.70890116609 19224.20308219259 14669.149107257057 27893.26430043789 19830.440328501096 23135.436112854128 27606.79600318177 1.3561582550763407 1.647787431422564 0.5206595869200964 0.7911352298415535 0.6963576316489947 0.5313600718303707 1.0103767310492353 0.7183173420854624 0.838034088062508 1.0 14.752735840508985 -5.257440765517383 24.999993915147737 0.7523667470031473 1.5019728990454542 0.7529910510857715 0.16914069841474103 145.45833800454952 909420.2009854818 0.04147967707069406 0.10160532565166422 5.527887990141913e-06 5.257440765517383 0.7496061520423069 ILLLFGET(ph)ELSPTATPR ddPTM_PC-9_AZD4547_30min_R2 1 ILLLFGETELSPTATPR 17 0 Q8NCF5;H3BSZ7;Q8NCF5-3;Q8NCF5-2 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 ILLLFGET(0.508)ELS(0.488)PT(0.003)ATPR 142.57 0.00026891 573820.0 4076.0 5399.5 7781.1 10119.0 7453.6 6174.4 5807.7 5938.9 4313.7 7674.6 True False 5372.083213933212 7144.78278202257 7677.917529919579 7786.220886991546 6418.796298501218 5788.313791932462 6324.574048994304 5021.1794673453915 4541.713375406908 7405.914589966435 0.7253774194494943 0.9647400999874279 1.0367277986599595 1.0513516990245 0.8667121691083813 0.78157987397998 0.8539896014413755 0.6779958648386395 0.6132548951563714 1.0 12.854462196129179 -6.604429544652259 3.324131065264578 0.7687503815218989 0.9535351067804574 0.2492852207788422 0.12754648092304066 0.3137852821191622 6.948502577839815 0.04500420572163519 0.0455061450252807 2.486396898271104e-07 6.604429544652259 0.1847847252585585 ILLLFGETELS(ph)PTATPR ddPTM_PC-9_AZD4547_30min_R2 2 ILLLFGETELSPTATPR 17 0 Q8NCF5;H3BSZ7;Q8NCF5-3;Q8NCF5-2 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 ILLLFGET(0.431)ELS(0.563)PT(0.006)ATPR;ILLLFGET(0.004)ELS(0.553)PT(0.442)ATPR 236.75 2.1581e-37 604910.0 9542.3 6692.77 13110.8 20222.3 18310.3 13060.5 9342.199999999999 14367.7 11364.699999999999 13315.6 True False 12576.552907829953 8856.077018249322 12936.942225555464 15560.361166420515 15768.23090378433 12243.824870357275 10173.637701760528 12147.502101900749 11965.414840505116 12849.42489695321 0.97876387532426 0.6892197191135947 1.006810991877388 1.210977245379294 1.227154602656436 0.9528694839300138 0.7917582135658733 0.9453732131452127 0.9312023640328289 1.0 13.649416169561539 -10.620772295455373 14.519067106409967 0.9999999988651946 0.9713691940218387 0.003249230512818002 0.15448263038620855 0.0 0.0 0.16659517674887617 0.04040526562186974 2.3945709226306454e-11 10.620772295455373 -0.028630804843355895 ILLLFGETELS(ph)PTATPR ddPTM_PC-9_Lapatinib_30min_R1 2 ILLLFGETELSPTATPR 17 0 Q8NCF5;H3BSZ7;Q8NCF5-3;Q8NCF5-2 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 ILLLFGET(0.007)ELS(0.938)PT(0.055)ATPR;ILLLFGET(0.001)ELS(0.497)PT(0.497)AT(0.005)PR 220.52 3.6440999999999993e-81 0.0 8746.7 8790.1 9117.8 7610.0 9853.6 9358.2 7390.6 7193.5 11288.0 5075.5 True False 8621.970454051669 8769.747063512135 8368.169679725816 8169.664786215806 9274.030620922962 8957.97160102969 7773.249105516469 7527.736271162846 10016.626572090352 5952.793412321357 1.4483906725547588 1.4732154227559993 1.4057550968264756 1.372408585405613 1.5579291903070516 1.5048349540382304 1.3058153655100901 1.2645720672216847 1.6826766659426635 1.0 12.539351112138961 -11.47252994561025 2.7747609746681454 0.6816485986675221 1.4391566101616033 0.5737104997350515 0.11523821903237534 3405955.6249306495 4112220.5512675163 7014000.084436455 0.028910106820614446 3.368759865612494e-12 11.47252994561025 0.7575080114940812 ILLVDS(ph)PGMGNADDEQQEEGTSSK ddPTM_PC-9_AZD4547_30min_R2 1 ILLVDSPGMGNADDEQQEEGTSSK 24 0 Q9UKN8 Q9UKN8 GTF3C4 General transcription factor 3C polypeptide 4 1 ILLVDS(1)PGMGNADDEQQEEGTSSK 88.014 0.00025694 0.0 6559.4 6044.4 8661.3 11923.0 10867.0 7972.2 7162.3 10143.0 8091.8 7729.6 True False 8645.152756004298 7998.134095315722 8546.445502807115 9174.336558513707 9358.30462807405 7473.697073730889 7799.7308247863875 8575.632412952615 8519.516028262886 7458.989056707134 1.1590247271150724 1.072281248103426 1.145791398516953 1.2299705079020233 1.2546344493774324 1.0019718512672344 1.0456820308340389 1.1497043832289033 1.1421810601266567 1.0 12.86476439480648 -6.766050472322275 24.9999969847133 1.0758752874224429 1.168508338888905 0.3843992390656389 0.06560380311590128 159.07956389419235 862475.2014802995 0.024996751025283974 0.02277131225760924 1.713758128420082e-07 6.766050472322275 0.09263305146646217 ILNDLSS(ph)DAPGVPR ddPTM_PC-9_AZD4547_30min_R2 1 ILNDLSSDAPGVPR 14 0 C9JBT4;C9J896;P16220;P16220-1;C9J4L5;H7C3I0;E7EWP8;P16220-3 C9JBT4 CREB1 Cyclic AMP-responsive element-binding protein 1 1 ILNDLS(0.228)S(0.772)DAPGVPR 96.435 0.0029504 2129900.0 19450.0 20042.0 27999.0 37569.0 24125.0 29801.0 17549.0 31628.0 22838.0 23202.0 True False 25634.69541486775 26520.184557328714 27627.71496577839 28908.0474852639 20775.660177812315 27937.538758969193 19110.827003082297 26740.619339136872 24045.17005529894 22389.705042139172 1.1449322519712186 1.1844811938082997 1.2339472500321407 1.2911312333439275 0.9279112939947579 1.2477850291635626 0.8535542101655305 1.1943265571747792 1.0739386700291071 1.0 14.450547902065729 -6.248837564479439 24.987537805172774 1.0594106493484936 1.2129931564071643 0.33145309927808975 0.11361633857415455 943.1874730771751 1870201.0731453986 0.03190727297225923 0.04088832974188795 5.638485079175987e-07 6.248837564479439 0.15358250705867071 ILNDLSS(ph)DAPGVPR ddPTM_PC-9_Lapatinib_30min_R1 1 ILNDLSSDAPGVPR 14 0 C9JBT4;C9J896;P16220;P16220-1;C9J4L5;H7C3I0;E7EWP8;P16220-3 C9JBT4 CREB1 Cyclic AMP-responsive element-binding protein 1 1 ILNDLS(0.364)S(0.636)DAPGVPR 81.327 0.010551000000000001 1928400.0 14974.0 15889.0 16319.0 9640.1 14560.0 16526.0 16041.0 12667.0 14700.0 10427.0 True False 14760.468014104717 15852.209996717247 14977.314813161676 10349.06511243088 13703.609426061372 15819.22150398758 16871.52449078419 13255.555063156999 13044.331202137502 12229.29305689583 1.2069763922928982 1.2962490900304766 1.2247081449010084 0.8462521148428338 1.1205561402696296 1.2935515920985692 1.3795993286194665 1.0839183427436536 1.066646382701745 1.0 13.578053387438546 -7.981340700407055 24.983969364510042 1.0473094374309537 1.1910183369180616 0.19730902509205206 0.13600728006527035 436.6271389032471 584623.863179389 0.0823444369420897 0.03954689755363846 1.0439009662930677e-08 7.981340700407055 0.14370889948710786 ILNPEEIEK ddPTM_PC-9_Lapatinib_30min_R1 2 ILNPEEIEK 9 0 O14818;H0Y586;O14818-2 O14818 PSMA7 Proteasome subunit alpha type-7 0 ; 103.88 0.012627 10576300.0 87573.0 78771.0 78814.0 73088.0 77856.0 73576.0 76444.0 66421.0 66470.0 69233.0 False True 86324.1929610787 78588.61058917567 72334.21715083803 78463.13533442048 73276.66315078526 70429.32599403297 80401.89627663535 69507.16214178194 58983.44863986945 81199.83180282645 1.0631080267591624 0.9678420366683582 0.8908173273866336 0.9662967717094372 0.9024238292601316 0.8673580280936177 0.9901731874503301 0.8560013068815556 0.7263986553949527 1.0 16.309189118567296 -1.5228787453035628 0.5600583128464697 0.8857559497800622 9.133912499799667 0.31957535626278977 0.07453769165867956 172.7160023180177 1.5317830967392416 0.03634263477307516 1720.2474533340267 0.029999999998395657 1.5228787453035628 8.248156550019605 ILNS(ph)LTLPNKK ddPTM_PC-9_AZD4547_30min_R2 1 ILNSLTLPNKK 11 1 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 ILNS(0.899)LT(0.101)LPNKK 57.106 0.035638 6954100.0 37177.0 24842.0 56524.0 59219.0 64055.0 50732.0 58628.0 37942.0 43669.0 45866.0 True False 48998.51267036188 32871.69068821275 55774.454827874484 45566.97447442954 55162.06891978316 47559.7200201344 63845.77842251464 32078.93572042275 45977.254187969564 44260.24530052389 1.107054701971611 0.7426911094824786 1.2601478922940876 1.0295237670969297 1.2463118662184691 1.0745471403786244 1.4425084630463836 0.7247798900030733 1.038793478793154 1.0 15.433723826460373 -7.789572131572557 24.99999591256874 0.9113402887828438 1.1177533095923347 0.20287338042401715 0.18751449612590415 363.8995882170441 323372.048797481 0.1006894977467002 0.048384347933999344 1.623408697626797e-08 7.789572131572557 0.20641302080949087 ILPEAHQR ddPTM_PC-9_Lapatinib_30min_R1 1 ILPEAHQR 8 0 P26640;A0A140T936 P26640 VARS Valine--tRNA ligase 0 114.28 0.0017835999999999998 0.0 14185.0 10281.0 11575.0 9790.6 9649.5 11209.0 11180.0 7720.7 10673.0 8071.2 False True 13982.719298789585 10257.194976162755 10623.348180792113 10510.63338448417 9081.935381646928 10729.617199455204 11758.84569583987 8079.431907801078 9470.89434832746 9466.296165802018 1.4771056233486142 1.083548918870502 1.122228588111374 1.1103216295360512 0.9593969196163931 1.133454628032563 1.242180203311188 0.853494520590732 1.0004857425169154 1.0 13.20858434409837 -2.4714717213745585 1.3006908782012732 1.050017792907797 199.99999955097306 0.5990932750600086 0.1030379144902493 501.6826919639493 2.4207154018177124 0.030873376194682296 296116.87549421005 0.0033769783676330933 2.4714717213745585 198.94998175806526 ILPNGEKTT(ph)RS(ph)WLLY(ph)S(ph)TSK ddPTM_PC-9_Lapatinib_30min_R1 1 ILPNGEKTTRSWLLYSTSK 19 2 Q9UJ78-5;Q9UJ78 Q9UJ78-5 ZMYM5 Zinc finger MYM-type protein 5 4 ILPNGEKT(0.118)T(0.896)RS(0.933)WLLY(0.928)S(0.569)T(0.492)S(0.065)K 51.606 0.04056 0.0 3321.1 3951.4 2864.8 3269.1 3126.6 3572.6 2488.2 3826.9 4033.1 2368.7 True False 3273.7405049848485 3942.25077607329 2629.2672024477984 3509.5205193979123 2942.6995351321075 3419.8082261373625 2617.026821143898 4004.711744785308 3578.8498075742 2778.126638905644 1.1783985867089328 1.4190320631410152 0.9464173323227323 1.2632687330554442 1.059238802839921 1.2309763630805861 0.9420113484008755 1.4415151882215271 1.2882241426488663 1.0 11.439896649696633 -14.489560693339705 21.87914551695706 0.003698799505810202 1.183603015779479 0.0 0.1747309814816269 0.0 0.0 0.0 0.03827115418663925 3.2392115077915237e-15 14.489560693339705 1.1799042162736688 ILPPLS(ph)PPQHR ddPTM_PC-9_Lapatinib_30min_R1 1 ILPPLSPPQHR 11 0 A0A087WV20;A0A087WTU9;Q8TCU4-3;Q8TCU4-2;Q8TCU4 A0A087WV20 ALMS1 Alstrom syndrome protein 1 1 ILPPLS(1)PPQHR 72.321 0.029463999999999997 0.0 13327.0 11742.0 14220.0 12509.0 11269.0 9838.4 10164.0 9492.7 11234.0 5845.3 True False 13136.954536127518 11714.812120426328 13050.886490787376 13428.953588800727 10606.179575706436 9417.63456643056 10690.242187166048 9933.765496805117 9968.708620735564 6855.652316627334 1.9162224000575188 1.7087815395792239 1.9036680811736109 1.9588148535816 1.5470708089998633 1.373703643574446 1.5593326051903922 1.4489891024246215 1.4540860825975654 1.0 12.743078229906455 -6.428382759343657 3.92744146073065 1.4103115191784248 1.8608228020420545 0.7028349764931625 0.15330426285096743 0.1402387578395466 3.904984835258921 0.04752071130158572 0.05344967610881158 3.7292134392901275e-07 6.428382759343657 0.45051128286362974 ILPTS(ph)ETK ddPTM_PC-9_Lapatinib_30min_R1 1 ILPTSETK 8 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 ILPT(0.214)S(0.723)ET(0.063)K 82.831 0.038826 0.0 54695.0 47133.0 61279.0 58276.0 50976.0 51749.0 45490.0 39555.0 51014.0 38011.0 True False 53915.03927016545 47023.86643434288 56240.877163780526 62561.81144303711 47977.691902672 49535.815902810915 47845.249615720546 41392.86970262688 45268.26611876482 44581.15070352622 1.2093684981061055 1.0547925679859909 1.2615393787790243 1.4033242851689938 1.0761878315284743 1.1111381182651439 1.073217017970246 0.9284836539527196 1.0154126890938293 1.0 15.444146234658682 -7.020765633447286 1.3909025983363519 0.9865131313018617 1.2141374196084047 0.5258236890208297 0.09195019225849484 0.36443919874326663 1.4295189110986024 0.05222563880811685 0.03762843277805368 9.533104782166952e-08 7.020765633447286 0.22762428830654302 ILS(ph)DVTHSAVFGVPASK ddPTM_PC-9_AZD4547_30min_R2 2 ILSDVTHSAVFGVPASK 17 0 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 1 ILS(0.896)DVT(0.087)HS(0.016)AVFGVPASK;ILS(0.548)DVT(0.452)HSAVFGVPASK 178.85 3.0714999999999997e-06 86600700.0 20680.2 25731.4 26562.1 38970.4 37182.4 32757.6 30474.0 32277.9 30609.4 34216.6 True False 27256.073425118175 34048.57184504782 26209.869198632165 29986.376366678098 32020.265574942536 30709.26209358104 33186.126964039555 27290.09222735317 32227.350393671386 33018.68724872247 0.8254741692122465 1.0311909613052592 0.7937889535461848 0.9081637964828025 0.9697619209916177 0.9300570268664821 1.005071059126482 0.8265044585747138 0.9760336669628893 1.0 15.010995142519997 -6.012406241811139 24.243767315056765 0.9437201280492795 0.8903755153316512 0.1395922323688955 0.07479975433273374 959.0231366523612 1874091.8793083616 0.020779945920643656 0.028339829306566318 9.718377352950677e-07 6.012406241811139 -0.05334461271762836 ILS(ph)DVTHSAVFGVPASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ILSDVTHSAVFGVPASK 17 0 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 1 ILS(1)DVTHSAVFGVPASK 206.81 2.4194000000000002e-17 10672000.0 17734.0 17550.0 19020.0 24355.0 24948.0 18393.0 23006.0 20319.0 16079.0 12820.0 True False 20736.015937534165 19292.248016090645 19473.508933751677 22990.468309975357 20059.618490716493 17428.43870097404 20826.705130983846 19785.64777976007 16314.124956520556 15144.164516935838 1.3692413281924476 1.2739063944079565 1.2858754216499892 1.518107405942727 1.3245774283740555 1.1508352726546043 1.375229720179887 1.306486584825041 1.0772548685849486 1.0 13.886474368344901 -8.326643838154308 3.1236726533512966 1.0046174099955099 1.326625610870538 0.6381287422590731 0.08743785155187808 0.16309746939850706 2.9517007236323485 0.08542595756121711 0.023496444547763316 4.713637300068252e-09 8.326643838154308 0.32200820087502824 ILS(ph)DVTHSAVFGVPASK ddPTM_PC-9_Lapatinib_30min_R1 4 ILSDVTHSAVFGVPASK 17 0 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 1 ILS(0.89)DVT(0.11)HSAVFGVPASK;ILS(0.55)DVT(0.366)HS(0.084)AVFGVPASK;ILS(0.935)DVT(0.049)HS(0.017)AVFGVPASK;ILS(0.777)DVT(0.195)HS(0.028)AVFGVPASK 122.75 5.4088e-05 138327510.0 46486.7 47263.200000000004 51531.8 42755.2 45465.899999999994 42448.6 39860.399999999994 37403.4 44516.0 37035.5 True False 45823.79113338328 47153.764964242386 47295.054322500495 45899.5600351661 42791.685151398604 40633.172330519636 41924.1764735649 39141.2985118249 39502.1393057383 43437.03682829824 1.054947447601447 1.0855658766650211 1.0888186159993503 1.0566917862422784 0.9851428245565959 0.9354499131959215 0.9651711888010799 0.9011042504244957 0.9094114651946875 1.0 15.406638068812127 -6.373789027344209 2.017887607498998 0.9365360830228184 1.0780911406489833 0.8299524463187237 0.027662279085205313 0.12233193471299328 0.9815954847454932 0.009694222160389131 0.011628227848968798 4.228739891581631e-07 6.373789027344209 0.14155505762616483 ILS(ph)PDSFIK ddPTM_PC-9_AZD4547_30min_R2 1 ILSPDSFIK 9 0 Q8IZT6-2;Q8IZT6 Q8IZT6-2 ASPM Abnormal spindle-like microcephaly-associated protein 1 ILS(0.998)PDS(0.002)FIK 84.31 0.013306 2212600.0 19296.0 26344.0 22813.0 25973.0 20002.0 21429.0 20229.0 30046.0 21505.0 18013.0 True False 25431.726618266737 34859.18281500189 22510.484714250597 19985.326128849847 17225.06755965191 20089.041242439875 22029.34181123438 25403.081088393385 22641.710396672355 17382.370352730497 1.4630758695273003 2.0054332123654275 1.2950181279916495 1.1497468828070658 0.99095044059662 1.1557135669522887 1.267338191754378 1.461427904992426 1.3025674828701195 1.0 14.08533720870722 -5.405405666278262 6.074173925636125 1.2039754086406906 1.729735394872893 0.5889009659913894 0.1790070631588602 0.15470127938987507 7.085247610398555 0.047982287837419785 0.10126357637159865 3.9318263939279124e-06 5.405405666278262 0.5257599862322024 ILS(ph)PSMASK ddPTM_PC-9_AZD4547_30min_R2 1 ILSPSMASK 9 0 A0A494BZT8;Q9Y6A5;E7EMT0;C9JA91;Q8IX09;C9JWI7 A0A494BZT8 TACC3;ERIC-1s Transforming acidic coiled-coil-containing protein 3 1 ILS(0.955)PS(0.045)MASK 133.91 0.001145 34825000.0 171870.0 172390.0 196130.0 304810.0 278180.0 235020.0 189880.0 268890.0 199780.0 210940.0 True False 226521.08488191845 228111.69622981243 193529.18805093472 234540.76376755547 239559.50873632415 220324.1622473386 206778.9521536993 227339.22897750494 210339.96294104654 203555.0548051395 1.1128246611157067 1.1206388190564989 0.9507461666142244 1.1522227438276007 1.1768782109864637 1.0823811890019235 1.0158379626172684 1.1168439378483317 1.0333320542808537 1.0 17.63505952225598 -8.466708113521362 4.394878378232226 1.0002994645233299 1.0892705415087591 0.19476237385331074 0.06213670179598038 0.32688446541958266 12.894637283708631 0.061587972905376286 0.016095022152752554 3.4142230222189708e-09 8.466708113521362 0.08897107698542928 ILS(ph)PSMASK ddPTM_PC-9_Lapatinib_30min_R1 2 ILSPSMASK 9 0 A0A494BZT8;Q9Y6A5;E7EMT0;C9JA91;Q8IX09;C9JWI7 A0A494BZT8 TACC3;ERIC-1s Transforming acidic coiled-coil-containing protein 3 1 ILS(0.333)PS(0.333)MAS(0.333)K;ILS(0.97)PS(0.029)MAS(0.001)K 105.13 0.0026565 39962300.0 290740.0 239260.0 276120.0 220810.0 298850.0 324400.0 306580.0 273490.0 342180.0 294180.0 True False 286593.994284814 238706.00817009117 253418.47945402333 237049.10400056661 281272.2305617065 310526.1682133346 322453.2122925395 286197.3438243319 303640.0850848581 345028.6210297893 0.8306383204657964 0.6918440779134134 0.7344853847128917 0.6870418555221832 0.8152141979474272 0.9000011862393414 0.9345694607309093 0.8294887043577234 0.8800431807036734 1.0 18.396356516632196 -6.553930081511479 3.372986669109096 0.8994230467024918 0.733185114039038 0.6849179389900214 0.05502801702504949 0.14285094285640393 3.3990935517404273 0.01838305545836742 0.019125985834218033 2.792993458191945e-07 6.553930081511479 -0.16623793266345388 ILSDVT(ph)HSAVFGVPASK ddPTM_PC-9_Lapatinib_30min_R1 3 ILSDVTHSAVFGVPASK 17 0 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 1 ILS(0.022)DVT(0.972)HS(0.005)AVFGVPASK;ILS(0.157)DVT(0.838)HS(0.004)AVFGVPASK;ILS(0.13)DVT(0.87)HSAVFGVPASK 120.71 0.00017137 8541020.0 72456.0 73557.0 82690.0 69677.0 73354.0 66519.0 64941.0 61900.0 72843.0 54087.0 True False 71422.76415319693 73386.68328582878 75891.54739263077 74801.2790156582 69039.46193951287 63674.137433362586 68303.32722124654 64776.099977059894 64638.65426920421 63435.865883602695 1.1259050878922225 1.1568642165377652 1.1963507762609056 1.179163836951634 1.0883348241228725 1.0037561014804637 1.07673043111881 1.0211273870828275 1.0189606994221296 1.0 15.953011133195906 -6.474064524311094 3.427035191943785 1.0290841778279283 1.165723107013941 0.8625577144482774 0.02632457142172315 0.08897400612418806 2.1048900713387786 0.009023944094210427 0.009908191413094503 3.356877364987817e-07 6.474064524311094 0.13663892918601284 ILSDVTHSAVFGVPASK ddPTM_PC-9_AZD4547_30min_R2 1 ILSDVTHSAVFGVPASK 17 0 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 0 116.86 0.00011245 1672300.0 15936.0 14254.0 19545.0 26176.0 21367.0 19938.0 17565.0 21830.0 17273.0 21536.0 False True 21003.31651060837 18861.326747837717 19285.820529523855 20141.527615168583 18400.56087126698 18691.273708141598 19128.250972086196 18456.67510349557 18186.015516471594 20782.03119504823 1.0106479156673034 0.9075785985891427 0.9280045991904353 0.9691799336711486 0.8854072394834684 0.8993959027737001 0.9204225897150957 0.8881073717131787 0.8750836405637197 1.0 14.343049046872082 -4.758360480699676 24.968842347271 0.9159392857081491 1.0106480471806774 0.3499408197365349 0.03712954778169961 91.57238090057471 742490.544155703 0.008968402596416663 0.06184761911593913 1.74437365632716e-05 4.758360480699676 0.09470876147252827 ILSDVTHSAVFGVPASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ILSDVTHSAVFGVPASK 17 0 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 0 ; 157.37 2.3429000000000002e-05 8102000.0 84202.0 87519.0 80119.0 93784.0 112552.0 82279.0 91246.0 96955.0 87688.0 78802.0 False True 98455.73553469323 96207.3079270792 82029.34081299968 88529.58653183056 90498.24356129258 77964.14439609855 82602.51831616745 94410.03398231379 88970.27111060235 93088.17880371143 1.0576609919751465 1.033507252622751 0.8812004044677816 0.9510293108054756 0.9721776140031693 0.8375300215132162 0.8873577652684089 1.0142000326527998 0.9557633660253229 1.0 16.506310352230635 -5.138171724655056 5.869670106166253 0.9344974303683256 1.0512736445846327 0.40763054846394475 0.0523146887921355 0.21654425412407333 9.32235916385922 0.013882088614847077 0.03834474421849596 7.2749208955173666e-06 5.138171724655056 0.11677621421630713 ILSDVTHSAVFGVPASK ddPTM_PC-9_Lapatinib_30min_R1 1 ILSDVTHSAVFGVPASK 17 0 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 0 82.94200000000001 0.0034658000000000002 1669600.0 14620.0 13181.0 14267.0 16568.0 15469.0 15448.0 11632.0 14957.0 14280.0 11881.0 False True 14411.516119020367 13150.480204338228 13094.022332212613 17786.4659892278 14559.14383322413 14787.325051046848 12234.248044186883 15651.95682321301 12671.63602493358 13934.615019562612 1.0342242034522116 0.9437275580183917 0.9396759303238803 1.276423206831163 1.044818519405434 1.0611936555324368 0.8779753173669593 1.1232428596871493 0.9093639118945192 1.0 13.766385524291845 ILSHGGFR ddPTM_PC-9_AZD4547_30min_R2 1 ILSHGGFR 8 0 B4DY09;Q12905 B4DY09 ILF2 Interleukin enhancer-binding factor 2 0 77.923 0.018828 0.0 7821.4 8391.0 8593.3 10488.0 9704.9 9841.9 6268.2 9443.3 9815.3 8075.6 False True 10308.44250477361 11103.226655051656 8479.34722723753 8070.153637984723 8357.542153767912 9226.484437163146 6826.057656887602 7984.054970446164 10334.116719667902 7792.875702021334 1.3228034038961742 1.4247919612232074 1.0880896284587391 1.0355809519573715 1.0724593171170578 1.1839640191835679 0.8759356517282886 1.0245325699696763 1.3260979790794578 1.0 12.927940089902796 -5.270147972602516 22.579368386889062 1.0718732655921137 1.37379768896907 0.5223654786235719 0.11391851576102872 113.58994905309517 294515.96764629555 0.02959590535595434 0.06344380023007014 5.368488503288358e-06 5.270147972602516 0.30192442337695624 ILSPS(ph)MASK ddPTM_PC-9_AZD4547_30min_R2 1 ILSPSMASK 9 0 A0A494BZT8;Q9Y6A5;E7EMT0;C9JA91;Q8IX09;C9JWI7 A0A494BZT8 TACC3;ERIC-1s Transforming acidic coiled-coil-containing protein 3 1 ILS(0.362)PS(0.54)MAS(0.098)K 89.9 0.008988600000000001 37786000.0 134090.0 129080.0 162220.0 210600.0 208670.0 155240.0 145820.0 202720.0 141750.0 151010.0 True False 176727.8307547358 170802.58570302316 160068.85680733479 162049.42373756508 179699.7724063878 145532.81825919877 158797.69750922878 171394.28204217248 149242.61561163943 145723.18586386708 1.2127639792327414 1.1721030163489903 1.0984446699982888 1.112035965841083 1.2331584115534042 0.9986936354462759 1.0897215605591808 1.1761634294921814 1.024151474090473 1.0 17.152870915803348 -1.5228787469106535 0.06433357665036799 0.8508959459970946 1.6928017202316377 0.3996694721738121 0.0631082942243536 332.5295900512463 1.5966102703106773 3.9742986701912124 25.806107096611456 0.029999999887381765 1.5228787469106535 0.841905774234543 ILSPS(ph)MASK ddPTM_PC-9_Lapatinib_30min_R1 1 ILSPSMASK 9 0 A0A494BZT8;Q9Y6A5;E7EMT0;C9JA91;Q8IX09;C9JWI7 A0A494BZT8 TACC3;ERIC-1s Transforming acidic coiled-coil-containing protein 3 1 ILS(0.327)PS(0.52)MAS(0.153)K 104.07 0.0027276999999999996 29366000.0 256710.0 187180.0 269320.0 211680.0 286650.0 280840.0 290350.0 245930.0 309890.0 241190.0 True False 253049.26832515193 186746.59621030508 247177.5492052638 227247.6533437793 269789.81057558337 268829.12787001557 305382.9023065387 257356.80561160517 274986.9249136321 282879.37013452663 0.8945483306358161 0.6601633626428662 0.8737913587962091 0.8033376673445963 0.9537274154961588 0.9503313293654843 1.079551690748287 0.9097758012159604 0.9720996083343186 1.0 18.109827441945626 -6.286352210639809 1.869938882380847 0.9844728951520981 0.792454832075313 0.574076986245597 0.07136871727335263 0.23922815727462698 1.646714265431908 0.024070595357291752 0.031067406187065983 5.171872255863538e-07 6.286352210639809 -0.19201806307678515 ILSPSMAS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 ILSPSMASK 9 0 A0A494BZT8;Q9Y6A5;E7EMT0;C9JA91;Q8IX09;C9JWI7 A0A494BZT8 TACC3;ERIC-1s Transforming acidic coiled-coil-containing protein 3 1 ILS(0.148)PS(0.049)MAS(0.803)K 65.719 0.044363 18892000.0 161100.0 123630.0 168780.0 208470.0 201490.0 176650.0 135830.0 204370.0 149860.0 176060.0 True False 212326.44891183503 163590.97978358195 166541.8669211072 160410.46232939293 173516.59147056603 165604.04757464209 147918.60686242336 172789.31245540013 157781.2936547462 169896.19298849322 1.2497422406999759 0.9628878487857682 0.9802566142985134 0.9441674913825601 1.0213094738521775 0.9747366592602705 0.8706410912482403 1.0170287480608988 0.9286923437150382 1.0 17.374293999600752 -4.761076375336884 24.99736039141562 0.9658531345142285 1.2497425591844433 0.7996468151297107 0.0425112385682733 3.571574847537215 245617.24733330228 0.010196894481699607 0.05803492747202886 1.7334991165574065e-05 4.761076375336884 0.28388942467021483 ILSPSMAS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ILSPSMASK 9 0 A0A494BZT8;Q9Y6A5;E7EMT0;C9JA91;Q8IX09;C9JWI7 A0A494BZT8 TACC3;ERIC-1s Transforming acidic coiled-coil-containing protein 3 1 ILS(0.104)PS(0.104)MAS(0.793)K 66.19 0.043247 19383000.0 184150.0 176310.0 167810.0 195100.0 225490.0 214480.0 218360.0 233990.0 229990.0 173080.0 True False 215322.9578717106 193812.89160780256 171811.2268229687 184169.17952273434 181306.85319350893 203232.29122953906 197675.36001050315 227848.01043289775 233353.16865166757 204458.03389947428 1.053140117632053 0.9479348300057233 0.840325144217336 0.9007676343659093 0.8867680557011124 0.9940049180432896 0.9668260827925893 1.1143998897344558 1.141325504315473 1.0 17.641445227148054 -7.571366484996033 2.2112379850212633 1.0966015377273037 0.9280904462597266 0.49202633100919835 0.06590610771069866 0.2517114908575944 2.4541267403117777 0.040289431008165656 0.020296546430958372 2.68307933899166e-08 7.571366484996033 -0.16851109146757715 ILSQS(ph)TDSLNMR ddPTM_PC-9_AZD4547_30min_R2 3 ILSQSTDSLNMR 12 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF5;V9GYG5;V9GZ14 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 ILS(0.026)QS(0.653)T(0.182)DS(0.138)LNMR;ILSQS(0.756)T(0.065)DS(0.179)LNMR;ILS(0.005)QS(0.764)T(0.072)DS(0.159)LNMR 179.67 0.00030365 51228100.0 91797.0 114052.0 144711.0 196472.0 161270.0 184787.0 126423.0 157473.0 144550.0 133363.0 True False 120986.53650378488 150917.0785915806 142792.03758751234 151178.41586214074 138880.4442228306 173232.23967832117 137674.4020861972 133139.16621954893 152190.61789532614 128694.00196253807 0.9401101423437218 1.1726815258687153 1.1095469517614203 1.1747122131313295 1.0791524243939337 1.3460785820363865 1.069781030869436 1.0345405705722386 1.1825773973493168 1.0 16.973585289918105 -11.078450569245499 2.9277503546336536 0.9936674168194448 1.1268834064524067 0.11450968172736153 0.10236422265062084 416883693.6981194 459876745.315258 20806628.18861956 0.024883129144781108 8.347365513482375e-12 11.078450569245499 0.13321598963296188 ILSQS(ph)TDSLNMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ILSQSTDSLNMR 12 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF5;V9GYG5;V9GZ14 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 ILS(0.016)QS(0.479)T(0.479)DS(0.026)LNMR;ILS(0.004)QS(0.772)T(0.18)DS(0.043)LNMR;ILS(0.028)QS(0.682)T(0.246)DS(0.043)LNMR;ILS(0.001)QS(0.827)T(0.145)DS(0.026)LNMR 84.734 0.0088484 119803200.0 117872.9 109797.9 189356.0 151567.5 191963.0 164137.0 172309.0 137810.3 146123.6 125964.0 True False 137826.4538741046 120697.9098829583 193870.9651766291 143075.6643634651 154349.22816792532 155529.3667733253 155986.6441108711 134192.92564708283 148260.38121130835 148800.2760695245 0.926251331749596 0.811140362579463 1.3028938540816017 0.9615282185136225 1.037291275560592 1.0452222998609004 1.0482953945461022 0.9018325045605653 0.996371681071587 1.0 17.183017677520958 -10.336398473946353 13.63814030284578 0.9999999999285678 1.0059024905080864 0.0 0.12235170594240725 0.0 0.0 0.11778619857893362 0.028567349292995307 4.608945005006609e-11 10.336398473946353 0.005902490579518638 ILSQS(ph)TDSLNMR ddPTM_PC-9_Lapatinib_30min_R1 7 ILSQSTDSLNMR 12 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF5;V9GYG5;V9GZ14 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 ILS(0.002)QS(0.719)T(0.191)DS(0.089)LNMR;ILS(0.007)QS(0.696)T(0.224)DS(0.072)LNMR;ILS(0.002)QS(0.392)T(0.392)DS(0.213)LNMR;ILS(0.003)QS(0.437)T(0.437)DS(0.122)LNMR;ILSQS(0.512)T(0.044)DS(0.444)LNMR;ILSQS(0.934)T(0.062)DS(0.004)LNMR;ILSQS(0.459)T(0.315)DS(0.225)LNMR 232.13 1.9544e-16 233315400.0 591945.0 552553.0 586366.0 478389.0 535929.0 544579.0 522650.0 480591.0 565337.0 406136.0 True False 583503.7557505812 551273.5974772545 538157.250918217 513571.32291892066 504406.7098969533 521288.62564565305 549710.2596539092 502921.01234370196 501662.79379747016 476336.0664577961 1.2249833612006793 1.1573207159741659 1.1297848070169139 1.078170138864393 1.0589303338877958 1.094371521187006 1.1540387099842129 1.0558113226311014 1.0531698712801922 1.0 18.86162026296634 -1.5228787452803376 0.4281881408526097 1.0638234946745924 4.221435983179122 0.6718884267159955 0.03579497175602701 53.365603497964024 0.6731229488341708 0.02496424314727711 145.18402977622327 0.029999999999999995 1.5228787452803376 3.1576124885045296 ILSQST(ph)DSLNMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ILSQSTDSLNMR 12 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF5;V9GYG5;V9GZ14 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 ILS(0.015)QS(0.245)T(0.569)DS(0.171)LNMR 106.79 0.0062255 31047000.0 43068.0 57036.0 74202.0 76930.0 93841.0 70752.0 88337.0 60055.0 58358.0 55914.0 True False 50358.56176822612 62698.157142207725 75971.25709265203 72619.86151042502 75453.52969325511 67041.64056822233 79969.07985550388 58478.6198835322 59211.3753475108 66050.76558501956 0.7624220752355297 0.9492419442361133 1.1501949511071596 1.0994552578947752 1.142356625619009 1.0150017183665696 1.2107214677560227 0.8853586989579916 0.896452521376074 1.0 16.011287663191272 -4.875835763643151 3.2896165929685743 1.055467230304753 0.749727187207287 0.4278968925002792 0.10119369128764419 0.27006777387831626 4.9241830746934 0.027032493150269465 0.18470890259775055 1.3309576486601553e-05 4.875835763643151 -0.30574004309746594 ILSQSTDS(ph)LNMR ddPTM_PC-9_Lapatinib_30min_R1 1 ILSQSTDSLNMR 12 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF5;V9GYG5;V9GZ14 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 ILSQS(0.341)T(0.023)DS(0.636)LNMR 190.34 0.00016591 9076400.0 26739.0 19721.0 26089.0 22258.0 19603.0 22702.0 21642.0 17230.0 25249.0 21805.0 True False 26357.69695666795 19675.337236154628 23944.0631264523 23894.927570511358 18449.990080980853 21731.088380946763 22762.516864880723 18030.568701207456 22405.191736242843 25573.965196663816 1.0306456880650785 0.7693502780992806 0.936267135046225 0.9343458234481569 0.7214364272063567 0.8497348070130961 0.8900659983634508 0.7050361006809999 0.8760937759923774 1.0 14.64238824470696 -4.7459546464691655 24.97437071694081 0.8463711713261683 1.0306461970097895 0.2488525435897765 0.09151128302313878 1195.9740979713795 1928805.658956744 0.022015345333993 0.5311637854568696 1.7949210613052396e-05 4.7459546464691655 0.1842750256836212 ILTFDQLALDSPK ddPTM_PC-9_Lapatinib_30min_R1 2 ILTFDQLALDSPK 13 0 F8VUA6;G3V203;H0YHA7;J3QQ67;Q07020-2;Q07020 F8VUA6 RPL18 60S ribosomal protein L18 0 ; 165.35 0.00091251 30129700.0 142034.0 123177.0 143326.0 134019.0 135402.0 125523.0 144344.0 121083.0 135829.0 144099.0 False True 140008.56911415473 122891.79122447221 131542.28953435944 143875.20433427827 127437.92057057431 120154.67389840446 151817.4260393838 126708.95821522357 120530.50767722017 169006.32015015176 0.8284220909003029 0.7271431690559879 0.7783276354250668 0.8513007336438896 0.7540423367442917 0.7109478142098733 0.898294370911711 0.7497291113293895 0.7131715995599229 1.0 17.366717672889777 -11.165574363055685 3.08538398024649 1.017415061260838 0.779527110377627 0.5563540649723061 0.059191991584478305 79528494.55637357 89555104.29363148 11120390.59323599 0.014584826128115234 6.830077584168306e-12 11.165574363055685 -0.2378879508832109 ILTTNTWSSELSK ddPTM_PC-9_Lapatinib_30min_R1 2 ILTTNTWSSELSK 13 0 O60701;O60701-2;O60701-3 O60701 UGDH UDP-glucose 6-dehydrogenase 0 ; 182.02 0.00034512 11065100.0 49684.0 43319.0 45270.0 39670.0 48053.0 47825.0 34301.0 32234.0 41829.0 40894.0 False True 48975.49704907028 43218.69751701143 41548.075347253485 42587.46413524061 45226.61701583295 45779.63623552015 36076.937943918 33731.70931600241 37117.77754110268 47962.47341217018 1.0211211717167834 0.9010940104278475 0.8662621502066014 0.8879330256649005 0.9429583963940645 0.9544886445306604 0.7521909396516591 0.7032937819141579 0.7738920639502357 1.0 15.549618439624776 -7.261545996299763 24.99975101655574 0.782618674447675 0.9236281737964971 0.31825740373122324 0.08393615947029318 9.895715999888568 2319960.958317437 0.032576276775796026 0.023556101436203472 5.475881026188455e-08 7.261545996299763 0.14100949934882212 ILVHAPHPPLS(ph)VVR ddPTM_PC-9_Lapatinib_30min_R1 1 ILVHAPHPPLSVVR 14 0 F2Z2E2;Q86VI3 F2Z2E2 IQGAP3 Ras GTPase-activating-like protein IQGAP3 1 ILVHAPHPPLS(1)VVR 64.22399999999999 0.04173 31837000.0 57292.0 82819.0 80783.0 78162.0 70986.0 70962.0 73631.0 80414.0 83981.0 75141.0 True False 56475.00557393398 82627.23769388403 74141.33357139767 83910.29422078827 66810.74304384564 67927.12068050135 77443.25290074998 84150.32800574001 74522.17542086463 88129.02173091115 0.6408218821079394 0.9375712571299611 0.8412817039746249 0.9521300994012605 0.7581014940554123 0.7707690309771814 0.8787485822458285 0.9548537627330134 0.8456031163991244 1.0 16.42732957023307 -14.522878744747961 0.09242088747434385 1.501261611382488 0.7268600408104743 0.2756852998935121 0.0894048354737065 308.85364026046983 1.9662970220608458 30.147042173246692 1.960417699474134 3.000000003677524e-15 14.522878744747961 -0.7744015705720136 ILVSIGESFGT(ph)SEK ddPTM_PC-9_AZD4547_30min_R2 2 ILVSIGESFGTSEK 14 0 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 ILVSIGES(0.011)FGT(0.851)S(0.138)EK;ILVSIGES(0.003)FGT(0.884)S(0.113)EK 230.67 1.4189e-20 7110000.0 35618.0 39780.0 45601.0 52220.0 55209.0 54417.0 44525.0 47296.0 49173.0 48581.0 True False 46943.78309957634 52638.107059701426 44996.30094483592 40181.485790957486 47544.18332670841 51014.29638759861 48487.63874364576 39987.48995395907 51772.18439133089 46880.19397690558 1.0013564176526677 1.122821869841928 0.9598147347044316 0.8571100582636655 1.0141635367406954 1.0881844135015653 1.034288355708 0.8529719389313526 1.1043508995896056 1.0 15.516690918783603 ILVSIGESFGT(ph)SEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ILVSIGESFGTSEK 14 0 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 ILVSIGES(0.001)FGT(0.887)S(0.113)EK;ILVSIGESFGT(0.957)S(0.042)EK 218.2 3.5925e-15 5396700.0 34349.0 31882.0 36123.0 41654.0 40504.0 31873.0 41117.0 35808.0 32786.0 26932.0 True False 40163.60727632576 35047.03425920238 36984.30931724036 39320.26142409006 32567.53196039684 30201.523770790267 37222.10009869871 34868.077941712116 33265.43322498183 31814.558406405315 1.262428563781024 1.1016036687199864 1.1624963906396453 1.2359203897098128 1.023667578357458 0.9492988519592247 1.1699706663602372 1.0959786867477634 1.0456041162050016 1.0 14.95739947632969 -1.522878745282285 0.2391188400888245 1.027435683692953 2.208469057234701 0.39298575361558774 0.07591982028365554 61.33271934194509 0.8180399369646643 0.11143891170037971 28.7101166192043 0.029999999999865478 1.522878745282285 1.181033373541748 ILVSIGESFGT(ph)SEK ddPTM_PC-9_Lapatinib_30min_R1 1 ILVSIGESFGTSEK 14 0 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 ILVSIGES(0.008)FGT(0.947)S(0.045)EK 155.06 0.00076934 2638100.0 12519.0 12592.0 11655.0 13813.0 11489.0 10312.0 9717.8 10053.0 10704.0 9437.5 True False 12340.47676429657 12562.843997650178 10696.770889601044 14828.854098817206 10813.239608243077 9870.979798446086 10220.94013443942 10520.099080280823 9498.402801882983 11068.759300321704 1.1148925032580577 1.1349821291429698 0.9663929442652305 1.3397033666082356 0.9769152363742157 0.891787374774623 0.9234043181463306 0.950431642322827 0.8581271436272826 1.0 13.434205898725159 -6.5045585785760185 24.79059661348074 0.9229883125900255 1.130369172754434 0.5551070028102962 0.09101340234079013 500.68251015509577 677517.660453519 0.027185727009616554 0.030256447391531063 3.129258361982523e-07 6.5045585785760185 0.2073808601644086 ILVSIGESFGTS(ph)EK ddPTM_PC-9_Lapatinib_30min_R1 1 ILVSIGESFGTSEK 14 0 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 ILVSIGESFGT(0.251)S(0.749)EK 240.46 2.3139e-27 2815100.0 19587.0 14492.0 14797.0 16865.0 15578.0 14374.0 12823.0 13477.0 12835.0 8153.1 True False 19307.685788184124 14458.444664385832 13580.44777807178 18105.30835999076 14661.732667526381 13759.257527430562 13486.912196579126 14103.190620207375 11389.387141458159 9562.352471677132 2.0191355469662757 1.5120175403710023 1.4201994559702649 1.8933947910430127 1.5332767444991362 1.4388988032164995 1.4104178063427597 1.4748662174898715 1.1910653968458649 1.0 13.2231498695747 -4.992490863605336 0.05940624501715425 9.856968255821179e-12 3.4336654732359344 0.6550454109635147 0.16493081587462677 104.35710684975386 1.0517583365556071 19.857124075873347 44.032936172635814 1.017440770188791e-05 4.992490863605336 3.4336654732260774 ILYSQCGDVMR ddPTM_PC-9_Lapatinib_30min_R1 1 ILYSQCGDVMR 11 0 F8W1R7;G3V1V0;P60660-2;P60660;J3KND3;G8JLA2;B7Z6Z4;F8VPF3;F8W1I5;P14649 F8W1R7 MYL6;MYL6B Myosin light polypeptide 6;Myosin light chain 6B 0 91.63600000000001 0.037246 7500800.0 27043.0 26326.0 29534.0 23805.0 26527.0 21531.0 24705.0 17922.0 24539.0 17852.0 False True 26657.361860921184 26265.043764464634 27105.82852453686 25555.699111152073 24966.734014088615 20610.169321212437 25984.10401750661 18754.721547477675 21775.159412874313 20937.694413705227 1.273175610179506 1.2544382034381145 1.2945947146307641 1.2205593703967725 1.1924299553128492 0.9843571557583531 1.2410203102638724 0.8957395774771343 1.0399979569202664 1.0 14.353814965989848 -6.7273317015123855 0.7323409283679031 0.9927326503951294 1.2897279351250412 0.6250286923610733 0.08388557522265318 0.43930664804547076 0.5194698856541728 0.05725491366746827 0.059181896335261455 1.8735629884623694e-07 6.7273317015123855 0.2969952847299119 IMADIR ddPTM_PC-9_AZD4547_30min_R2 1 IMADIR 6 0 P05783;F8VZY9;CON__P05784 P05783 KRT18 Keratin, type I cytoskeletal 18 0 111.69 0.019981 0.0 31462.0 30018.0 42472.0 55264.0 51728.0 43196.0 38148.0 51944.0 38750.0 42675.0 False True 41466.26154974649 39720.731466016055 41908.7935292882 42523.73862028867 44546.460090274646 40494.94729144769 41543.0980975317 43917.24835437351 40798.245890307124 41180.96123925907 1.0069279662713513 0.9645411440311176 1.0176739995407214 1.032606751776097 1.081724630745315 0.9833414780236507 1.0087937932329611 1.0664454406301194 0.9907064979195509 1.0 15.329689885064228 -5.425895907065075 6.058136913519947 1.0262251823532098 0.9860982216214913 0.18079020018373515 0.031199647831716536 0.34511675668750447 17.714654637109156 0.008105405770972017 0.017071778785668765 3.7506288761123605e-06 5.425895907065075 -0.04012696073171851 IMADIR ddPTM_PC-9_Lapatinib_30min_R1 1 IMADIR 6 0 P05783;F8VZY9;CON__P05784 P05783 KRT18 Keratin, type I cytoskeletal 18 0 111.69 0.019981 0.0 47489.0 46533.0 46702.0 47085.0 46514.0 48509.0 43611.0 39945.0 43878.0 42758.0 False True 46811.79815158397 46425.25569747898 42862.34183493332 50547.78797095548 43778.13797004252 46434.383150002 45868.96418973819 41800.990526391906 38935.99758417613 50148.66332854629 0.933460536024639 0.9257526046771455 0.8547055692017748 1.0079588291275952 0.8729671952217826 0.9259346125696237 0.9146597565169409 0.8335414695409716 0.7764114734043662 1.0 15.613923627047376 -7.731710445679975 11.706498815517616 0.8537450176056076 0.9190073601320536 0.09283504075755578 0.06501320939862174 1.1802382411314014 461.99650121994995 0.02902930236860768 0.016633816661135736 1.8547678284913344e-08 7.731710445679975 0.06526234252644603 IMAT(ph)PEQVGK ddPTM_PC-9_AZD4547_30min_R2 6 IMATPEQVGK 10 0 P12956;B1AHC9;P12956-2 P12956 XRCC6 X-ray repair cross-complementing protein 6 1 IMAT(1)PEQVGK;IMAT(1)PEQVGK;IMAT(1)PEQVGK;IMAT(1)PEQVGK;IMAT(1)PEQVGK;IMAT(1)PEQVGK 115.29 0.0043425 236159800.0 1097552.0 1052497.0 1377881.0 1849516.0 1506092.0 1427979.0 1300459.0 1450572.0 1299316.0 1347970.0 True False 1446550.7055002009 1392696.0725493876 1359609.3976485496 1423138.6609373519 1296997.1228402813 1338687.2473908279 1416197.3316771004 1226419.428228481 1367995.1911538127 1300777.980590134 1.1120657999176256 1.0706639359912538 1.0452278697335615 1.0940673060069064 0.997093387337217 1.0291435336132422 1.0887310154455438 0.9428353235746517 1.0516746220851492 1.0 20.310943310292025 -1.5228787842774005 0.23311895267912106 0.9996955812388004 1.6081631801164948 0.3621735211907975 0.03952740820563503 54.79132524071704 0.7219965652887643 0.05479742597808947 12.77626113466113 0.029999997306178444 1.5228787842774005 0.6084675988776944 IMAT(ph)PEQVGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 IMATPEQVGK 10 0 P12956;B1AHC9;P12956-2 P12956 XRCC6 X-ray repair cross-complementing protein 6 1 IMAT(1)PEQVGK;IMAT(1)PEQVGK;IMAT(1)PEQVGK;IMAT(1)PEQVGK;IMAT(1)PEQVGK 105.03 0.009622499999999999 126590000.0 499553.0 538709.0 562641.0 597388.0 688078.0 582469.0 608802.0 552518.0 534754.0 452780.0 True False 584117.4562785062 592188.469316249 576056.4952678742 563918.2871180264 553254.0553092521 551923.3002619285 551131.867215215 538014.9879412109 542573.7655948242 534865.4297954933 1.0920830245129967 1.1071728257753979 1.0770120168135198 1.0543180690022191 1.0343799103277058 1.0318918918969158 1.0304122056008391 1.0058885057254903 1.0144117293246606 1.0 19.02881643475886 -5.849072835439688 0.5319620578167851 1.005864786524904 1.123730371538374 0.9441612881609902 0.008247263287647426 0.33731115397280365 0.15612265706369818 0.006048291671311558 0.021953898000910386 1.4155563573783101e-06 5.849072835439688 0.11786558501347 IMAT(ph)PEQVGK ddPTM_PC-9_Lapatinib_30min_R1 7 IMATPEQVGK 10 0 P12956;B1AHC9;P12956-2 P12956 XRCC6 X-ray repair cross-complementing protein 6 1 IMAT(1)PEQVGK;IMAT(1)PEQVGK;IMAT(1)PEQVGK;IMAT(1)PEQVGK;IMAT(1)PEQVGK;IMAT(1)PEQVGK;IMAT(1)PEQVGK 112.94 0.005268600000000001 212868500.0 1758326.0 1408313.0 1554497.0 1378365.0 1407387.0 1451689.0 1336291.0 1202807.0 1509858.0 1066630.0 True False 1733251.9488025038 1405052.1377749897 1426692.257191947 1479734.5601908474 1324607.2636893035 1389603.645522341 1405477.6094579212 1258693.8042828334 1339801.892530403 1250995.57430486 1.3854980660228304 1.1231471690503254 1.1404454871750576 1.1828455596360448 1.0588424858539944 1.1107982106927126 1.1234872755156644 1.006153682823579 1.0709885151071696 1.0 20.25464525495922 -1.5228787452803376 0.660849338170876 1.0715096579439856 27.9322957324494 0.7347817525934215 0.053635129019887304 125.86069336517434 0.7792803658424619 0.022230174113933975 4957.787429863055 0.029999999999999995 1.5228787452803376 26.860786074505416 IMDQT(ph)LKALMAAEDKY(ph)SQK ddPTM_PC-9_Lapatinib_30min_R1 1 IMDQTLKALMAAEDKYSQK 19 2 P09493-3;P09493-4;P09493-10;P09493-8;H7BYY1;B7Z596;F5H7S3;H0YL42 P09493-3 TPM1 Tropomyosin alpha-1 chain 2 IMDQT(1)LKALMAAEDKY(0.837)S(0.164)QK 48.053000000000004 0.027464999999999996 19531000.0 49511.0 34546.0 38996.0 32989.0 43926.0 42500.0 43203.0 40083.0 41975.0 40393.0 True False 48804.96406079461 34466.010859499904 35789.89940891311 35415.12110807795 41342.35904183872 40682.37407233889 45439.83994609748 41945.40251018567 37247.33348365455 47374.87622971069 1.0301866293887447 0.7275166417824831 0.7554615918229635 0.7475506835386242 0.8726642121739469 0.858733094627598 0.9591548002314428 0.8853933951574109 0.7862254521373345 1.0 15.531834553693002 -6.443631599830798 6.130826394612798 0.891688215443966 0.8045979181734618 0.13869880022701064 0.09542242510945292 0.4536558534205269 28.066338629085113 0.029670526389212 0.03348215742062852 3.6005463017763367e-07 6.443631599830798 -0.08709029727050421 IMDY(ph)YET(ph)NSQCS(ph)KPGIVFIT(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 IMDYYETNSQCSKPGIVFITK 21 1 A0A087X089;Q16627;Q16627-2 A0A087X089 CCL14 C-C motif chemokine;C-C motif chemokine 14;HCC-1(3-74);HCC-1(4-74);HCC-1(9-74) 4 IMDY(0.675)Y(0.59)ET(0.632)NS(0.342)QCS(0.763)KPGIVFIT(0.999)K 40.968 0.045979 0.0 7207.8 7408.0 8556.2 14717.0 9132.6 8326.5 9088.9 9008.2 9134.7 10563.0 True False 9499.730468446465 9802.491128664358 8442.739197478233 11324.223025383402 7864.69613015083 7805.84263872209 9897.794492467643 7616.189677842825 9617.54159314034 10193.192585126977 0.9319681139261166 0.9616703546803681 0.8282723128175903 1.1109593908690323 0.7715635768156007 0.7657897732759115 0.9710200616546426 0.7471839283166011 0.9435259378080841 1.0 13.315318364846053 -6.303101342007187 24.99900637161187 0.8540622055754448 0.9491827852317044 0.14651966785653803 0.10499766635828557 890.1208126756984 534109.1728836178 0.031015085646905312 0.03516812123361483 4.976209522796836e-07 6.303101342007187 0.09512057965625964 IMNKMKNFK ddPTM_PC-9_Lapatinib_30min_R1 1 IMNKMKNFK 9 2 Q07002;Q07002-3;A0A0A0MSJ6;D6R9B0 Q07002 CDK18 Cyclin-dependent kinase 18 0 60.973 0.041858 0.0 10068.0 10714.0 11310.0 9679.4 11080.0 10082.0 8524.6 9959.6 10581.0 6232.4 False True 9924.428473754926 10689.1923912662 10380.135457862534 10391.25536553184 10428.296184118135 9650.816362289896 8965.96207681186 10422.35937530736 9389.256357130405 7309.6620358490045 1.357713725351766 1.4623374293972635 1.4200568243723048 1.4215780859046125 1.4266454636307828 1.3202821573636503 1.2265905089510036 1.4258332771327398 1.2844993805571832 1.0 12.835588988996278 -13.3966851551799 0.1816085139956496 2.609251093364396e-10 1.461028381993799 0.7925228458268492 0.060231273559510703 37.67714937672646 0.524991197321259 13.97045645714425 0.1959146059200312 4.011574341217962e-14 13.3966851551799 1.461028381732874 IMNT(ph)FSVVPSPK ddPTM_PC-9_AZD4547_30min_R2 1 IMNTFSVVPSPK 12 0 P04350;M0R2D3;M0R042;M0QYM7;P68371;A0A0B4J269;Q13509;Q13509-2;G3V2A3;Q5JP53;P07437;Q5ST81 P04350;P68371;A0A0B4J269;Q5JP53 TUBB4A;TUBB4B;TUBB3;TUBB Tubulin beta-4A chain;Tubulin beta-4B chain;Tubulin beta-3 chain;Tubulin beta chain 1 IMNT(0.962)FS(0.037)VVPS(0.001)PK 108.71 0.0015862 0.0 27181.0 30847.0 32249.0 46447.0 42201.0 36314.0 30467.0 42682.0 24411.0 31457.0 True False 35823.992600078156 40817.68950403749 31821.357188877733 35739.36174899659 36342.11959228428 34043.27983937477 33178.50397760033 36086.47763478689 25701.315623955772 30355.700004765604 1.1801405533212568 1.3446466231261158 1.0482827667911474 1.1773525810106766 1.1972090772599169 1.121478991887199 1.0929909035993757 1.1887875301548507 0.8466718151754323 1.0 14.889679821779781 -8.253381485775448 24.995663959619616 0.9233359027698187 1.1678209406015025 0.5915039517381809 0.08161156222949603 363.95791335660755 1129009.5102201109 0.05695726262958565 0.02067744967914355 5.579798479782888e-09 8.253381485775448 0.24448503783168385 IMNT(ph)FSVVPSPK ddPTM_PC-9_Lapatinib_30min_R1 2 IMNTFSVVPSPK 12 0 P04350;M0R2D3;M0R042;M0QYM7;P68371;A0A0B4J269;Q13509;Q13509-2;G3V2A3;Q5JP53;P07437;Q5ST81 P04350;P68371;A0A0B4J269;Q5JP53 TUBB4A;TUBB4B;TUBB3;TUBB Tubulin beta-4A chain;Tubulin beta-4B chain;Tubulin beta-3 chain;Tubulin beta chain 1 IMNT(0.852)FS(0.148)VVPSPK;IMNT(0.538)FS(0.459)VVPS(0.002)PK 105.14 0.0069777 11612600.0 65310.0 69082.0 80218.0 54660.0 73675.0 64749.0 66400.0 64796.0 72680.0 47951.0 True False 64378.66742361282 68922.04487338544 73622.78569043454 58679.87874041472 69341.58135062312 61979.83620729101 69837.86710230484 67806.65870942781 64494.01304567032 56239.26645930873 1.1447280783826235 1.2255146486174955 1.3090993237563553 1.043396943714973 1.232974498356845 1.1020740509148674 1.2417990400503394 1.2056817767793704 1.1467790585841693 1.0 15.779290156704933 -8.671354828119934 3.6090103360054235 1.000025888736041 1.188690552383421 0.3819062062993398 0.07176095728615718 0.8642622839263493 19.400346935163054 0.06676194176387822 0.017564239716636797 2.1313028803909143e-09 8.671354828119934 0.1886646636473801 IMNTFS(ph)VVPSPK ddPTM_PC-9_AZD4547_30min_R2 2 IMNTFSVVPSPK 12 0 P04350;M0R2D3;M0R042;M0QYM7;P68371;A0A0B4J269;Q13509;Q13509-2;G3V2A3;Q5JP53;P07437;Q5ST81 P04350;P68371;A0A0B4J269;Q5JP53 TUBB4A;TUBB4B;TUBB3;TUBB Tubulin beta-4A chain;Tubulin beta-4B chain;Tubulin beta-3 chain;Tubulin beta chain 1 IMNT(0.126)FS(0.84)VVPS(0.034)PK;IMNTFS(0.998)VVPS(0.001)PK 109.66 0.0012854000000000001 16723600.0 164662.0 191755.0 225670.0 300290.0 249120.0 239550.0 158521.0 237450.0 189259.0 216350.0 True False 217021.0908176321 253736.05377659746 222677.46834984154 231062.7799342519 214533.98812421193 224570.9006312223 172629.06190413143 200757.55855817834 199262.84436009362 208775.6523518152 1.0394942531513311 1.2153527047733417 1.0665873431189183 1.1067515648083326 1.0275814526623688 1.075656562925211 0.8268639564024838 0.9615946893073274 0.9544352615615771 1.0 17.671593947458383 -7.126730230128508 7.1169575226276764 0.932876573737706 1.093060650765114 0.5835479837228603 0.06331258376520507 0.17943465875067768 9.599938901959648 0.02405227949108505 0.01861694581753226 7.469125725939785e-08 7.126730230128508 0.1601840770274079 IMNTFS(ph)VVPSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IMNTFSVVPSPK 12 0 P04350;M0R2D3;M0R042;M0QYM7;P68371;A0A0B4J269;Q13509;Q13509-2;G3V2A3;Q5JP53;P07437;Q5ST81 P04350;P68371;A0A0B4J269;Q5JP53 TUBB4A;TUBB4B;TUBB3;TUBB Tubulin beta-4A chain;Tubulin beta-4B chain;Tubulin beta-3 chain;Tubulin beta chain 1 IMNT(0.235)FS(0.765)VVPS(0.001)PK 83.53 0.0096177 9262200.0 30510.0 33242.0 34537.0 41331.0 45479.0 40970.0 37108.0 37982.0 32913.0 29088.0 True False 35674.74040003199 36542.046071275494 35360.49306230187 39015.35806690992 36567.716423733196 38821.46107643702 33592.861601345234 36985.012745255524 33394.29035972144 34361.424139518705 1.0382206585844866 1.063461337426026 1.0290753060387317 1.1354406589347026 1.0642084063587183 1.1297977906506174 0.9776329835732985 1.0763527319206616 0.9718540833502597 1.0 15.068502211032905 -7.271958811086884 24.994907657780495 1.012822679073765 1.0760362820990725 0.4006157095856374 0.04179688385838192 816.7538388710207 1940656.4585916898 0.016921884196057082 0.011552831016005629 5.346150604074959e-08 7.271958811086884 0.06321360302530743 IMNTFSVVPSPK ddPTM_PC-9_Lapatinib_30min_R1 2 IMNTFSVVPSPK 12 0 P04350;M0R2D3;M0R042;M0QYM7;P68371;A0A0B4J269;Q13509;Q13509-2;G3V2A3;Q5JP53;P07437;Q5ST81 P04350;P68371;A0A0B4J269;Q5JP53 TUBB4A;TUBB4B;TUBB3;TUBB Tubulin beta-4A chain;Tubulin beta-4B chain;Tubulin beta-3 chain;Tubulin beta chain 0 ; 106.67 0.021946 22961200.0 135527.0 117902.0 141241.0 120590.0 128291.0 122547.0 137395.0 115850.0 118706.0 126345.0 False True 133594.36012739202 117629.00516287729 129628.71018602684 129458.59087644734 120745.17560981057 117305.95048100967 144508.64082110187 121232.81393121778 105336.0802504038 148183.56490587007 0.9015464043684907 0.7938060151110429 0.8747846650090397 0.8736366341212178 0.8148351383401455 0.7916259171894358 0.975200191147361 0.8181259103074482 0.7108486040089259 1.0 17.177025921111344 IMPDS(ph)NDSPPAEREPGEVVDSLVGK ddPTM_PC-9_AZD4547_30min_R2 1 IMPDSNDSPPAEREPGEVVDSLVGK 25 1 Q9Y657 Q9Y657 SPIN1 Spindlin-1 1 IMPDS(0.5)NDS(0.5)PPAEREPGEVVDSLVGK 56.247 0.0087213 5545500.0 12961.0 15179.0 17222.0 28792.0 24101.0 21105.0 17867.0 21036.0 19751.0 21779.0 True False 17082.3283944525 20085.314908476834 16993.6250273451 22154.44923196568 20754.992163542174 19785.30101365876 19457.12838703468 17785.369559190698 20794.997537534342 21016.52383901169 0.8128046543426757 0.955691581649373 0.8085840054957553 1.0541443200441039 0.9875559023236731 0.9414164380948916 0.9258014568002726 0.8462564834902336 0.9894594223490879 1.0 14.35923644490361 -3.7036760621453113 1.0083047016900346 0.9467283544432986 2.539653629023941e-18 0.24308057974651787 0.06927952768431199 22.266295936887808 3.4277676463029176 0.02208816696164108 37.711085605015846 0.00019784448009329422 3.7036760621453113 -0.9467283544432986 IMPDS(ph)NDSPPAEREPGEVVDSLVGK ddPTM_PC-9_Lapatinib_30min_R1 1 IMPDSNDSPPAEREPGEVVDSLVGK 25 1 Q9Y657 Q9Y657 SPIN1 Spindlin-1 1 IMPDS(0.5)NDS(0.5)PPAEREPGEVVDS(0.001)LVGK 53.443999999999996 0.015648 3261200.0 21751.0 16265.0 18688.0 15554.0 18235.0 17082.0 16673.0 15853.0 18973.0 11135.0 True False 21440.826751355118 16227.339391818612 17151.54477776614 16697.89304662295 17162.45315138937 16351.442680086891 17536.246358384444 16589.588254221817 16836.06094545271 13059.669913545142 1.6417587039560062 1.2425535636998029 1.3133214615154258 1.2785846163925123 1.314156733286875 1.252056352751122 1.342778682346046 1.270291543664173 1.2891643553709422 1.0 13.672830812413146 -14.522878745280336 0.10484460682351572 0.04000048185386976 1.508072518471252 0.5399613613191147 0.09962782153319831 148.32405139928184 1.042649359554157 31.252027210175388 1.4290399870089805 3.0000000000000132e-15 14.522878745280336 1.4680720366173823 IMPDSNDS(ph)PPAEREPGEVVDSLVGK ddPTM_PC-9_Lapatinib_30min_R1 1 IMPDSNDSPPAEREPGEVVDSLVGK 25 1 Q9Y657 Q9Y657 SPIN1 Spindlin-1 1 IMPDS(0.472)NDS(0.527)PPAEREPGEVVDS(0.001)LVGK 50.538999999999994 0.035771 3476900.0 17521.0 14426.0 18023.0 16545.0 19030.0 18315.0 14736.0 15462.0 16575.0 12969.0 True False 17271.14732704211 14392.597483330796 16541.218510791907 17761.774492502056 17910.692814419497 17531.710144350265 15498.95797619825 16180.420966806152 14708.148957512192 15210.674369893753 1.1354623014760357 0.9462169219674991 1.0874743688900261 1.1677177527156624 1.1775081353309258 1.1525925621713724 1.0189527169732258 1.063754346015835 0.9669623186874474 1.0 13.892796496355054 -7.282738387138056 22.65265557991146 1.0177301501822384 1.1081742341434748 0.3521745249820233 0.06537610947628107 349.8120166736192 372040.5428361601 0.030190372179008017 0.02039037014151831 5.2150876601934655e-08 7.282738387138056 0.09044408396123638 IMRSYNCTPVS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 IMRSYNCTPVSSPR 14 1 Q8N122-3;Q8N122;Q8N122-2 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 1 IMRSYNCT(0.003)PVS(0.995)S(0.002)PR 88.155 0.028125999999999998 15599000.0 21826.0 16034.0 23970.0 20430.0 24869.0 22789.0 17186.0 14152.0 9152.1 10030.0 True False 28766.21399099762 21216.676938040542 23652.142138280215 15720.179140353532 21416.368620187135 21364.000227447013 18715.520706306477 11965.133580607842 9635.861321617534 9678.852752894401 2.972068562815491 2.1920652663814755 2.4436927332329947 1.6241779415078412 2.2126970176070406 2.2072864184299363 1.9336507315611053 1.2362140313612833 0.9955582100095478 1.0 13.240620337761309 -7.7319618132406935 1.8873466203239708 0.9777161091240849 2.2536870473120154 0.7521873362674595 0.30948047718916366 0.18193557785851908 1.2633306577333476 0.22654771267269488 0.0943297994055377 1.8536946083957593e-08 7.7319618132406935 1.2759709381879305 up IMRSYNCTPVS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IMRSYNCTPVSSPR 14 1 Q8N122-3;Q8N122;Q8N122-2 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 1 IMRSYNCTPVS(0.999)SPR 88.596 0.040391 0.0 18474.0 14879.0 13602.0 17688.0 8981.5 22687.0 15718.0 7953.4 17203.0 15645.0 True False 21601.28332186796 16356.088788114681 13926.323265872263 16696.99870526973 7221.639549237218 21497.253781819054 14229.07725153456 7744.631677323872 17454.561330121473 18481.314654248134 1.1688174637999935 0.8850067808544699 0.7535353153392226 0.9034529749447093 0.3907535629548542 1.1631885601210559 0.7699169413937688 0.4190519896561408 0.944443707423668 1.0 14.173779764967081 -4.719982322265894 2.038391682052308 0.7731427514508504 1.327105186191551 0.19211996597113734 0.22854454553476794 1.3893495893936254 5.587178156233081 0.05913753200349506 1.5280075353217735 1.9055382803428868e-05 4.719982322265894 0.5539624347407006 IMRSYNCTPVS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 IMRSYNCTPVSSPR 14 1 Q8N122-3;Q8N122;Q8N122-2 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 1 IMRSYNCTPVS(0.999)SPR 97.734 0.012685 13976000.0 15140.0 19129.0 25864.0 17658.0 15430.0 21642.0 24129.0 22653.0 23781.0 10284.0 True False 14924.100823664041 19084.707975782265 23737.56175792719 18956.628225361204 14522.437736547192 20716.422109966068 25378.281555896254 23705.5410788423 21102.533354968153 12061.575697431359 1.2373259678536268 1.5822731999971245 1.9680315701191806 1.571654375920239 1.2040249218549364 1.7175552041992201 2.104060215059698 1.9653768026254352 1.7495668795132764 1.0 13.55813076957165 -6.986997442027749 24.993270496777534 1.8031431861771532 1.5366734502897488 0.04408985885841077 0.3397671248519683 508.8558332533423 978108.9167516306 0.11861551352630237 0.1045489381143359 1.0303921893809548e-07 6.986997442027749 -0.2664697358874044 IMS(ph)CSPDTQCSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IMSCSPDTQCSR 12 0 Q9C0C9;K7EQ12 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 1 IMS(0.828)CS(0.168)PDT(0.004)QCSR 82.831 0.01029 9786000.0 21069.0 23834.0 27977.0 27046.0 35342.0 28476.0 32106.0 26032.0 26378.0 22718.0 True False 24635.56556828168 26200.082006581433 28644.077783363336 25530.700304315083 28416.988804669785 26982.668430866976 29064.687252689197 25348.687583183928 26763.728347726807 26836.593564410956 0.9179840768223227 0.9762819541048747 1.0673514771766472 0.9513390826983471 1.0588895619880256 1.0054431225075353 1.0830244599759116 0.9445568239629266 0.9972848559743894 1.0 14.711913937837927 -4.904089703672261 3.819160740599726 1.013619759438621 0.9187158137474708 0.31113122668405435 0.043654790263665776 0.27338172784935133 6.996321426809358 0.010616440038927236 0.057860122590038164 1.2471258933625495e-05 4.904089703672261 -0.09490394569115013 IMS(ph)CSPDTQCSR ddPTM_PC-9_Lapatinib_30min_R1 1 IMSCSPDTQCSR 12 0 Q9C0C9;K7EQ12 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 1 IMS(0.899)CS(0.101)PDTQCSR 169.09 0.00099556 6867000.0 19396.0 30526.0 33429.0 35533.0 31509.0 31577.0 20196.0 24697.0 32002.0 24172.0 True False 19119.409483209223 30455.318922511862 30680.596659671668 38146.215354613174 29655.702569077475 30226.52531958222 21241.650060213065 25844.512780831148 28397.597764000282 28350.097992834573 0.6744036471422996 1.0742579771755774 1.0822042543706947 1.3455408642416173 1.0460529122888003 1.0661876839798545 0.7492619625364909 0.9116198747307079 1.0016754711457334 1.0 14.791066101437664 -7.141362351405337 23.58295756901188 0.908163541643684 1.0642789834711694 0.1281572591745901 0.16562249471368617 21.019535476408045 4053.7226474857284 0.06534859375145188 0.05061880579640182 7.221670157720607e-08 7.141362351405337 0.1561154418274855 IMS(ph)SPLSK ddPTM_PC-9_Lapatinib_30min_R1 1 IMSSPLSK 8 0 J3QRI7;J3QQQ9;J3QQV1;E5RIT6;J3QRC4;Q9UNX3;P61254;E5RHH1;J3KSS0 J3QRI7 RPL26;RPL26L1 60S ribosomal protein L26-like 1;60S ribosomal protein L26 1 IMS(0.68)S(0.319)PLSK 78.939 0.021419 2961200.0 48253.0 33311.0 72231.0 45067.0 46241.0 44991.0 45119.0 43746.0 64985.0 39353.0 True False 47564.903371483524 33233.87042612174 66292.44599972312 48381.37751910485 43521.19529330385 43066.839809143465 47455.041051037515 45778.59886262458 57665.70497761263 46155.11361542357 1.0305446059088206 0.7200474188631624 1.4362968868864465 1.0482343933162226 0.9429333368331358 0.9330892383450204 1.0281643209990832 0.9918424043772005 1.2493892975347933 1.0 15.494202875284419 IMSCS(ph)PDTQCSR ddPTM_PC-9_AZD4547_30min_R2 3 IMSCSPDTQCSR 12 0 Q9C0C9;K7EQ12 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 1 IMS(0.077)CS(0.846)PDT(0.077)QCSR;IMS(0.22)CS(0.558)PDT(0.22)QCS(0.002)R;IMS(0.001)CS(0.991)PDT(0.005)QCS(0.003)R 105.03 0.0018398 30417200.0 36870.0 35391.0 48721.0 69139.0 58075.0 47860.0 43818.0 59797.0 44719.0 50750.0 True False 48593.89305635855 46830.448641274364 48074.92770626414 53200.071736901795 50012.288697469485 44867.3066341487 47717.71711328625 50556.74764836119 47082.75504435209 48973.25794709779 0.9922536317443076 0.9562453184524063 0.9816567188198089 1.086308609371464 1.0212162881116482 0.9161593186758282 0.9743627259765358 1.0323337627031866 0.9613972404125559 1.0 15.579706554109029 IMSCS(ph)PDTQCSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IMSCSPDTQCSR 12 0 Q9C0C9;K7EQ12 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 1 IMS(0.231)CS(0.752)PDT(0.017)QCSR;IMS(0.02)CS(0.969)PDT(0.012)QCSR;IMS(0.076)CS(0.92)PDT(0.004)QCSR 99.669 0.0028826999999999998 16622300.0 53864.5 49991.0 62163.0 57972.0 68281.0 62674.0 63403.0 56876.0 57097.0 44798.4 True False 62982.69597763106 54953.776100990675 63645.20167449033 54724.01678775984 54901.82820925982 59387.265108728636 57397.00884203113 55383.06526510333 57931.935608088424 52919.99529606074 1.1901493117161968 1.0384312355575989 1.2026683169268526 1.034089600378959 1.037449604863185 1.1222084351384911 1.0845996588042714 1.046543276416843 1.0947078752367305 1.0 15.69152531292813 -1.5228787807912278 0.05285523221728861 0.865523224460614 1.5036336052137247 0.2870839801728272 0.054789040571163114 613.4268936607626 2.449961982740446 6.682407383596521 31.34748637908684 0.029999997546994703 1.5228787807912278 0.6381103807531107 IMSCS(ph)PDTQCSR ddPTM_PC-9_Lapatinib_30min_R1 4 IMSCSPDTQCSR 12 0 Q9C0C9;K7EQ12 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 1 IMS(0.004)CS(0.933)PDT(0.063)QCSR;IMS(0.102)CS(0.728)PDT(0.17)QCSR;IMS(0.072)CS(0.925)PDT(0.002)QCS(0.001)R;IMS(0.02)CS(0.959)PDT(0.02)QCSR 101.45 0.0023916999999999996 25827600.0 65763.0 91869.0 114116.0 100248.0 104351.0 91869.0 80609.0 83545.4 104214.0 67902.0 True False 64825.20756054277 91656.2829749146 104733.82298049857 107620.57233752438 98213.27934195944 87939.97702709878 84782.53959713377 87427.22428147755 92476.32189792919 79638.77022627246 0.8139905648512542 1.1509002802843082 1.3151110028811992 1.351359043236718 1.2332345045373305 1.1042357482070684 1.0645887594226613 1.0977972667467901 1.161197261524534 1.0 16.281183322830913 -6.8710530305000885 6.459390707452055 1.0886252260895204 1.1892090236132822 0.0820364702090336 0.14148477056100178 0.5725994899618427 30.56192977254728 0.053640157548202706 0.04734718016826403 1.345696024797165e-07 6.8710530305000885 0.10058379752376179 IMSS(ph)IGEGIDFSQER ddPTM_PC-9_AZD4547_30min_R2 2 IMSSIGEGIDFSQER 15 0 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 IMS(0.247)S(0.753)IGEGIDFSQER;IMS(0.094)S(0.906)IGEGIDFSQER 93.71600000000001 0.0028084 10244400.0 16236.5 15450.2 32672.0 48070.0 43467.0 42964.0 38174.0 40798.0 37297.0 37357.0 True False 21399.369259820065 20444.175004871773 32238.747932494436 36988.204174096616 37432.35734503498 40277.454288122964 41571.41204716303 34493.606544773815 39268.443276665384 36049.14280058583 0.5936165910572583 0.567119587779478 0.8942999868493552 1.0260494785883099 1.0383702478613908 1.1172929828297726 1.1531872554397453 0.9568495632637695 1.0893031075353956 1.0 15.137677334104396 -5.421579933801162 2.181092702490853 1.0611538105728768 0.5609829469771487 0.9186145331647494 0.05569330251593483 0.08136700926612835 0.7396578689072125 0.016206928931883562 0.0458750800405362 3.7880880591225197e-06 5.421579933801162 -0.5001708635957282 IMSS(ph)IGEGIDFSQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IMSSIGEGIDFSQER 15 0 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 IMS(0.091)S(0.909)IGEGIDFSQER 69.878 0.021889 1972500.0 4824.9 4890.8 7434.0 8259.1 9640.8 9352.8 9635.7 11068.0 8762.6 8168.8 True False 5641.66027388117 5376.326301828839 7611.254753602001 7796.369403363472 7751.754447061866 8862.32270333659 8722.936739573197 10777.476727515359 8890.736447789483 9649.73877581478 0.5846438338850073 0.5571473411594903 0.7887524139698114 0.8079357985216737 0.8033123618320273 0.9184002706423828 0.9039557383082292 1.1168672000248379 0.9213447798268289 1.0 13.236274172956014 -5.3297926520579875 0.4272521646420394 1.0250079494872841 0.3416287265672677 0.8402993971283699 0.06558263758437563 1.2314179725451666 0.24864878877828073 0.053511202668711066 0.40937674295793586 4.679585083307614e-06 5.3297926520579875 -0.6833792229200164 INAWNS(ph)PTLPIYEPGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 INAWNSPTLPIYEPGLK 17 0 O60701;O60701-2;E7ER83;E7ETF4;E7EV97;E7ER95 O60701 UGDH UDP-glucose 6-dehydrogenase 1 INAWNS(0.88)PT(0.116)LPIY(0.004)EPGLK 95.34700000000001 0.012404 0.0 5548.3 5553.2 7795.2 7308.4 6871.5 8995.1 7545.8 8209.4 7102.8 6503.8 True False 6487.517606079896 6104.484996179746 7981.067131460631 6898.934042152492 5525.078902475482 8523.381121031454 6831.007197138917 7993.9119485782985 7206.6650128225765 7682.887455947532 0.8444113809135304 0.7945560873020597 1.0388108868212393 0.8979610962297567 0.7191409394131328 1.1093981487953821 0.8891197790292826 1.0404827604743832 0.9380151738710817 1.0 12.907432904915579 -6.770125022594964 24.99976162551835 0.9912905986185928 0.8675538386653033 0.3440097220340492 0.09373715979538023 250.03617857489382 719671.1712258485 0.03279635194317427 0.029359409975017674 1.6977548406544754e-07 6.770125022594964 -0.12373675995328948 INAWNSPTLPIYEPGLK ddPTM_PC-9_Lapatinib_30min_R1 1 INAWNSPTLPIYEPGLK 17 0 O60701;O60701-2;E7ER83;E7ETF4;E7EV97;E7ER95 O60701 UGDH UDP-glucose 6-dehydrogenase 0 88.163 0.012773 2443700.0 32328.0 31895.0 34658.0 32849.0 32652.0 33209.0 28904.0 26633.0 28115.0 32774.0 False True 31866.996791770893 31821.149087122943 31808.553023748864 35264.82504105167 30731.473556301928 31788.72848396002 30400.50769164181 27870.46640854664 24948.392635924884 38438.942231390036 0.8290289727522118 0.827836231693627 0.827508541527278 0.9174244397457348 0.7994880132577106 0.8269928004938879 0.7908778422840191 0.7250580996941961 0.6490395205399672 1.0 15.23028101590761 -7.208107159089791 2.1166118015493818 0.7655609167975216 0.8424013869849516 0.03978691362697018 0.08854210747888573 0.6923620724111026 6.06963536400821 0.0410120494718533 0.027544032653451827 6.192882512303333e-08 7.208107159089791 0.07684047018743001 INHEGEVNR ddPTM_PC-9_AZD4547_30min_R2 2 INHEGEVNR 9 0 Q09028-3;Q09028;Q09028-4;Q09028-2;E9PC52;Q16576;Q16576-2;Q5JP01 Q09028-3;E9PC52 RBBP4;RBBP7 Histone-binding protein RBBP4;Histone-binding protein RBBP7 0 ; 182.16 0.00080415 44174000.0 242990.0 214665.0 305700.0 401320.0 329340.0 305950.0 251770.0 333050.0 233840.0 282490.0 False True 320255.7654940216 284051.2632471296 301646.2182591685 308801.8743321914 283616.825822206 286818.89813451265 274177.0422568819 281584.77522763127 246200.30500617836 272600.11108326464 1.1748189104596538 1.0420071441583796 1.1065520738802335 1.1328017186239117 1.040413463865304 1.0521598725501067 1.0057847781769083 1.0329591360350632 0.9031555564222695 1.0 18.056426624471506 -7.073143643472846 0.7822215930852664 0.9660605911851259 1.1120965928561661 0.6234691649641217 0.044288993734056 0.44028939140780576 0.5527098683896415 0.03297613727870587 0.02359819879633315 8.449993142972426e-08 7.073143643472846 0.14603600167104025 INHEGEVNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 INHEGEVNR 9 0 Q09028-3;Q09028;Q09028-4;Q09028-2;E9PC52;Q16576;Q16576-2;Q5JP01 Q09028-3;E9PC52 RBBP4;RBBP7 Histone-binding protein RBBP4;Histone-binding protein RBBP7 0 ;;; 172.59 0.00032205 37248000.0 230000.2 246320.4 286842.4 295566.4 303866.8 272728.6 284581.3 268656.3 278826.5 230674.1 False True 268934.6911489825 270773.4614371878 293681.8106718596 279006.7728471975 244326.2818660752 258426.23210473894 257623.69907380885 261604.3567898793 282903.8100745869 272493.48831482866 0.9869398818010122 0.9936878239246084 1.0777571694944532 1.0239025327638054 0.8966316346752106 0.9483758078143983 0.9454306620940615 0.9600389293986781 1.0382039285567461 1.0 18.0558622291405 -6.135721146528549 21.92340580440482 0.9609187029022811 1.0227451831949355 0.29991041907652105 0.041455183086737325 7.462223355754125 1274.1688336802129 0.012647253586387271 0.01632758715563522 7.316086868246885e-07 6.135721146528549 0.06182648029265436 INHEGEVNR ddPTM_PC-9_Lapatinib_30min_R1 3 INHEGEVNR 9 0 Q09028-3;Q09028;Q09028-4;Q09028-2;E9PC52;Q16576;Q16576-2;Q5JP01 Q09028-3;E9PC52 RBBP4;RBBP7 Histone-binding protein RBBP4;Histone-binding protein RBBP7 0 ;; 167.93 4.8396e-16 27026600.0 369279.0 322036.0 357573.0 314813.0 321766.0 323305.0 285661.0 292584.0 346741.0 269417.0 False True 364013.013742525 321290.3454278324 328174.7282116959 337965.39820538176 302840.3564962954 309477.99881076533 300451.1288299924 306178.5207704054 307687.37723539904 315985.36947441276 1.1519932531939627 1.0167886758878855 1.0385757060763858 1.069560273526363 0.9583999316171449 0.9794061013822529 0.9508387344950213 0.968964231729085 0.9737393150422882 1.0 18.26949823576529 -1.5228787456336446 0.4380310420159638 0.9682801915838352 4.401594443688011 0.706991847691349 0.0319151355192994 47.24138289786254 0.584049042618212 0.02110006880997197 143.9295986261397 0.029999999975594417 1.5228787456336446 3.433314252104176 INHSS(ph)SLAR ddPTM_PC-9_AZD4547_30min_R2 1 INHSSSLAR 9 0 H0Y9X0;A0A286YEZ9;A0A2C9F2R7;O94915 H0Y9X0 FRYL Protein furry homolog-like 1 INHS(0.009)S(0.747)S(0.244)LAR 61.419 0.037362 2663000.0 6726.9 4419.1 18981.0 39416.0 26413.0 21339.0 11303.0 26105.0 13304.0 18619.0 True False 8865.914271787859 5847.487654789513 18729.299538034928 30329.25017112944 22746.010871567127 20004.668956667352 12308.945103187607 22071.07208322271 14007.222279345693 17967.15447718253 0.49345121861378594 0.3254542984096651 1.0424187960213893 1.6880385934036584 1.265977364443186 1.113402179631303 0.68508038481104 1.2284122180422041 0.7796015945170522 1.0 14.133074321690588 -5.29972516107711 6.1597438551072115 1.1235681561366748 0.4085089374321871 0.5230164238451509 0.2635337042964993 0.14183139695270808 15.920663890753115 0.07340930434177069 0.16002240758185085 5.015045053401471e-06 5.29972516107711 -0.7150592187044877 INHSS(ph)SLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 INHSSSLAR 9 0 H0Y9X0;A0A286YEZ9;A0A2C9F2R7;O94915 H0Y9X0 FRYL Protein furry homolog-like 1 INHS(0.006)S(0.497)S(0.497)LAR 59.265 0.042464 1545400.0 7580.3 6610.9 15200.0 13697.0 19694.0 13962.0 11862.0 9855.4 14759.0 7231.2 True False 8863.495072250495 7267.186462083965 15562.425646321011 12929.601496273151 15835.102074561908 13229.808141303727 10738.345486556998 9596.706192659458 14974.822453715205 8542.159317852294 1.0376176259937742 0.8507434937318766 1.8218374379645477 1.5136221434376111 1.8537586909047765 1.5487662602656795 1.2570996497472116 1.123452026070652 1.7530488365417467 1.0 13.060385090267054 -5.245920175723302 24.988680893586185 1.4968376435533035 0.9441804767592434 0.37862746138722303 0.27619555268784124 827.1234544329865 1331811.0921297157 0.07063169165486799 0.18542415084747166 5.676489309370448e-06 5.245920175723302 -0.5526571667940601 INISEGNCPER ddPTM_PC-9_Lapatinib_30min_R1 1 INISEGNCPER 11 0 Q15366-2;Q15366;Q15366-6;Q15366-3;Q15366-5;H3BRU6;F8VZX2;Q15366-8;Q15366-4;P57721-5;P57721-3;P57721;P57721-4;J3QT27;E9PFP8;F8W1G6;F8VTZ0;P57721-2;Q15366-7;F8W0G4;F8VXH9;Q15365 Q15366-2;Q15365 PCBP2;PCBP3;PCBP1 Poly(rC)-binding protein 2;Poly(rC)-binding protein 3;Poly(rC)-binding protein 1 0 105.13 0.011962 24045000.0 124250.0 70495.0 81943.0 98372.0 93217.0 78699.0 77501.0 58777.0 62484.0 58619.0 False True 122478.17221534035 70331.77315869983 75205.96284912735 105606.60503937224 87734.15933167323 75333.2272263294 81513.62256469452 61507.99399598792 55446.39393431018 68751.21604509234 1.7814691762689658 1.0229895150155721 1.0938855655993267 1.536068903422847 1.27611065488835 1.0957366510713071 1.1856317204808655 0.8946459064178042 0.806478737742532 1.0 16.069097611135327 -7.391722764122978 1.1789985708096984 0.8792884122967123 1.3190376424539159 0.42186830155000543 0.21360117833569092 0.5094276251582853 1.3488398388651288 0.1538494080784762 0.07870416502631808 4.057674781921705e-08 7.391722764122978 0.4397492301572036 INITEMY(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 INITEMYK 8 0 Q6ZMP0-3;Q6ZMP0-2;Q6ZMP0-4;Q6ZMP0 Q6ZMP0-3 THSD4 Thrombospondin type-1 domain-containing protein 4 1 INIT(0.006)EMY(0.994)K 52.482 0.035283 0.0 32168.0 30439.0 23742.0 38361.0 28500.0 30257.0 34459.0 38469.0 34796.0 29587.0 True False 42396.75486403424 40277.81148291233 23427.165567252792 29517.46412154192 24543.26694580937 28365.025006883334 37525.78424407165 32524.499979678007 36635.24552255807 28551.168135581902 1.4849394134314693 1.410723767645643 0.8205326470708104 1.0338443590598934 0.8596239155350816 0.9934803673245653 1.314334463160025 1.139165298779644 1.2831434899121128 1.0 14.801262152420769 -5.125869445271363 6.683753430123719 1.0603448464413703 1.465752749348082 0.5212445616448452 0.1509281284315981 0.19248272841185624 9.453451011117172 0.04152207394223657 0.1128535726450456 7.483944440763436e-06 5.125869445271363 0.4054079029067117 INLCIHS(ph)EEEDMNLGLVR ddPTM_PC-9_AZD4547_30min_R2 1 INLCIHSEEEDMNLGLVR 18 0 P41002 P41002 CCNF Cyclin-F 1 INLCIHS(1)EEEDMNLGLVR 60.45399999999999 0.018113999999999998 3288100.0 13176.0 11985.0 13660.0 19067.0 14375.0 12176.0 11709.0 15047.0 12588.0 14378.0 True False 17365.693922174683 15858.91687055107 13478.859474714562 14671.397732213441 12379.279380561751 11414.632795181667 12751.078316661391 12721.831895661839 13253.375981088668 13874.630596322593 1.2516148665447988 1.1430154309660974 0.9714751957639197 1.057426187339505 0.8922240700118403 0.822698140749568 0.9190211031665957 0.9169131968842256 0.9552237004855044 1.0 13.760161740637564 -4.89493279830774 0.8931683686205346 0.9148503599899174 1.40798967423377 0.7808097444328705 0.056550146262412504 0.8667851541726783 0.6082268171054045 0.020974100394281922 0.4046198644531741 1.2737001550928802e-05 4.89493279830774 0.4931393142438527 INNYLTVPAHKLDS(ph)PTMSR ddPTM_PC-9_AZD4547_30min_R2 1 INNYLTVPAHKLDSPTMSR 19 1 P19634 P19634 SLC9A1 Sodium/hydrogen exchanger 1 1 INNYLTVPAHKLDS(0.721)PT(0.214)MS(0.065)R 73.168 0.0024039 6071400.0 41191.0 62087.0 128530.0 138120.0 120260.0 81722.0 79990.0 140070.0 83011.0 91988.0 True False 54288.881173975235 82155.40857254092 126825.60821998991 106278.56793272776 103563.97483870314 76611.91042114301 87108.95503883706 118425.3999883933 87398.79198968473 88767.52811896829 0.6115849153895108 0.9255119559309385 1.428738761881657 1.197268530337927 1.1666876056287645 0.863062338724426 0.9813155427972673 1.3341072180096853 0.984580666395834 1.0 16.43774440309332 -4.905729815178456 3.937297187394836 1.1249090684890355 0.6193012482436903 0.4712718981766365 0.1647902864751973 0.20224583412058547 5.490732262762139 0.04315818793112648 0.22854158712072128 1.2424250090574533e-05 4.905729815178456 -0.5056078202453452 INNYLTVPAHKLDS(ph)PTMSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 INNYLTVPAHKLDSPTMSR 19 1 P19634 P19634 SLC9A1 Sodium/hydrogen exchanger 1 1 INNYLTVPAHKLDS(0.464)PT(0.237)MS(0.298)R;INNYLTVPAHKLDS(0.724)PT(0.212)MS(0.064)R 56.424 0.013581000000000001 11969000.0 79270.0 39366.0 67372.0 68869.0 160958.0 73766.0 66459.0 90156.0 68605.0 62444.0 True False 92688.84534613346 43273.99631916948 68978.40398973266 65010.49320631056 129419.43534667089 69897.58110237865 60163.5223985072 87789.50052817816 69608.21833709141 73764.60289356794 1.2565490995711124 0.586649891976072 0.9351152352742806 0.8813237061699045 1.7544924024522321 0.9475761864160124 0.8156150787568774 1.1901304566750832 0.9436534002294623 1.0 16.17064106195085 -4.4827607525281215 24.999389358192143 1.0156212024252227 3.6820106954593914 0.06248121434182197 0.2889590808044443 1837.7663919065292 1836352.433156397 0.07149156807158968 154854.72040783748 3.2903284109080764e-05 4.4827607525281215 2.6663894930341687 INNYLTVPAHKLDS(ph)PTMSR ddPTM_PC-9_Lapatinib_30min_R1 1 INNYLTVPAHKLDSPTMSR 19 1 P19634 P19634 SLC9A1 Sodium/hydrogen exchanger 1 1 INNYLTVPAHKLDS(0.453)PT(0.453)MS(0.094)R 68.329 0.0040323 4816800.0 83745.0 56524.0 29692.0 19345.0 26509.0 23678.0 18924.0 17375.0 40714.0 12585.0 True False 82550.7809430477 56393.1221508242 27250.8383744345 20767.695833028218 24949.792738699245 22665.347136113887 19903.792124156866 18182.30593055598 36128.36058257321 14760.300481541582 5.592757481209896 3.820594453435845 1.8462251773609146 1.4069968195430136 1.6903309502337083 1.5355613637038026 1.3484679494870344 1.2318384678749439 2.447671077411557 1.0 13.849434470786335 -5.003310025298526 1.8156399601552855 1.5171708269438746 6.053136570868522 0.9292249057355955 0.36433839126677 0.12406624622828175 0.5862891629394991 0.09841727439654498 0.8361869662148262 9.924073559487989e-06 5.003310025298526 4.535965743924647 INPPSSGGTSS(ph)SPIK ddPTM_PC-9_AZD4547_30min_R2 3 INPPSSGGTSSSPIK 15 0 A0A0C4DG88;P14859-4;P14859-5;P14859-3;P14859;P14859-2;P14859-6;A0A0A0MT46 A0A0C4DG88 POU2F1 POU domain protein;POU domain, class 2, transcription factor 1 1 INPPSS(0.007)GGT(0.025)S(0.153)S(0.546)S(0.269)PIK;INPPSSGGT(0.017)S(0.009)S(0.487)S(0.487)PIK;INPPSSGGT(0.001)S(0.004)S(0.802)S(0.191)PIK 123.72 3.126e-05 163463100.0 59590.0 51884.3 75699.0 92342.0 78679.0 85045.0 66477.0 84610.0 69814.0 78461.0 True False 78538.380451001 68654.88532221396 74695.18179915208 71053.97856967816 67755.77894839762 79727.12270583314 72393.32421698696 71535.46864437734 73504.22551189423 75714.10427166983 1.037301850249689 0.9067648093131144 0.9865425011321305 0.9384510224769923 0.894889791012822 1.0530022572777749 0.9561405356818649 0.9448103405899233 0.9708128520962708 1.0 16.208274454759326 -6.737661895327026 24.999820367035884 0.9797031571848762 0.9513116164530735 0.101378984230871 0.04648144670136508 643.5682600938172 676651.1215394188 0.015044126208405298 0.015036163726457684 1.8295239733161694e-07 6.737661895327026 -0.028391540731802722 INPPSSGGTSSS(ph)PIK ddPTM_PC-9_AZD4547_30min_R2 4 INPPSSGGTSSSPIK 15 0 A0A0C4DG88;P14859-4;P14859-5;P14859-3;P14859;P14859-2;P14859-6;A0A0A0MT46 A0A0C4DG88 POU2F1 POU domain protein;POU domain, class 2, transcription factor 1 1 INPPSSGGT(0.001)S(0.001)S(0.029)S(0.968)PIK;INPPSSGGTS(0.003)S(0.323)S(0.674)PIK;INPPS(0.016)S(0.018)GGT(0.001)S(0.009)S(0.059)S(0.897)PIK;INPPSSGGT(0.009)S(0.009)S(0.079)S(0.904)PIK 188.0 2.8484e-07 169823100.0 125793.2 106517.0 144814.0 149918.0 148543.0 143553.0 124448.0 142691.0 119661.0 130172.0 True False 165792.8209388971 140946.53719653632 142893.67174021344 115356.72131001075 127920.36848881979 134576.60821671452 135523.63091227913 120641.38466298167 125986.03616722689 125614.71790127293 1.3198518749148662 1.1220543225461324 1.1375551697096586 0.918337621875452 1.0183549398197032 1.0713442697255047 1.0788833759018122 0.9604080371999079 1.0029560092332954 1.0 16.93864598483833 -4.495318116040234 1.0574672175163335 1.0141474000059252 1.6338967941783022 0.7438335129785962 0.05459638065507894 1.5502339413318758 0.9500562379168647 0.017888827923741885 1.2483631742078756 3.196552811363908e-05 4.495318116040234 0.6197493941723771 INPPSSGGTSSS(ph)PIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 INPPSSGGTSSSPIK 15 0 A0A0C4DG88;P14859-4;P14859-5;P14859-3;P14859;P14859-2;P14859-6;A0A0A0MT46 A0A0C4DG88 POU2F1 POU domain protein;POU domain, class 2, transcription factor 1 1 INPPS(0.002)S(0.002)GGT(0.011)S(0.112)S(0.2)S(0.674)PIK;INPPS(0.012)S(0.023)GGT(0.007)S(0.07)S(0.216)S(0.672)PIK;INPPSSGGTS(0.001)S(0.171)S(0.828)PIK;INPPSSGGT(0.003)S(0.013)S(0.055)S(0.928)PIK;INPPSSGGTSS(0.239)S(0.76)PIK;INPPS(0.01)S(0.01)GGT(0.062)S(0.062)S(0.201)S(0.654)PIK 153.94 4.7267e-05 310986500.0 205371.0 198385.0 198323.0 242301.0 248544.0 207439.0 226849.0 199548.0 194552.0 185529.0 True False 240136.25403785502 218079.35171921007 203051.77246416576 228725.66052044037 199843.5873880327 196560.53366451117 205360.22047546555 194310.07643858306 197396.95494377692 219163.93905324384 1.0956923619606789 0.9950512509552483 0.9264834960592501 1.0436281694356369 0.9118452070688625 0.8968653078313154 0.9370164697832667 0.8865969341396863 0.9006817261840743 1.0 17.741650913114455 -1.5228787452807393 0.546179970136357 0.9203860697436291 8.272532082736534 0.5299003741129782 0.04604204113048787 101.27701072364361 0.9388593393603762 0.022879073128208912 872.2037447184747 0.02999999999997225 1.5228787452807393 7.352146012992905 INPPSSGGTSSS(ph)PIK ddPTM_PC-9_Lapatinib_30min_R1 4 INPPSSGGTSSSPIK 15 0 A0A0C4DG88;P14859-4;P14859-5;P14859-3;P14859;P14859-2;P14859-6;A0A0A0MT46 A0A0C4DG88 POU2F1 POU domain protein;POU domain, class 2, transcription factor 1 1 INPPSSGGTS(0.005)S(0.205)S(0.79)PIK;INPPSSGGT(0.002)S(0.035)S(0.162)S(0.802)PIK;INPPSSGGTSS(0.028)S(0.972)PIK;INPPS(0.001)S(0.001)GGT(0.006)S(0.006)S(0.022)S(0.963)PIK 236.75 5.529099999999999e-32 344449300.0 646902.0 705459.0 697907.0 598729.0 739214.0 657330.0 641174.0 658834.0 685535.0 547077.0 True False 637677.0588527016 703825.5530287719 640527.7804589256 642761.5279613932 695734.8858706404 629217.5282110703 674370.8524315243 689445.8328317651 608322.8292964178 641638.5305157198 0.9938260072071511 1.0969190900413492 0.9982688850435752 1.0017502026332035 1.084309705203396 0.9806417449795822 1.0510136476522003 1.074508153800583 0.9480771499296896 1.0 19.29140125294238 -8.26913771153652 24.97540130116815 0.9740385745325436 1.0352205197580029 0.2654732378028668 0.040663780069309235 833.1893848663627 2703043.4419794767 0.034771093548609605 0.0096520939616251 5.380991282465506e-09 8.26913771153652 0.06118194522545928 INPY(ph)MSSPCHIEMILTEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 INPYMSSPCHIEMILTEK 18 0 A0A087WXM6;J3QQT2;J3KRX5;A0A0A6YYL6;P18621;P18621-3;J3QLC8;A0A0A0MRF8;P18621-2 A0A087WXM6 RPL17;RPL17-C18orf32 60S ribosomal protein L17 1 INPY(0.629)MS(0.186)S(0.186)PCHIEMILTEK 53.778999999999996 0.015191 18485000.0 44316.0 32332.0 54748.0 48163.0 68162.0 50004.0 54530.0 61116.0 45672.0 33831.0 True False 51817.823519102545 35541.70728525597 56053.39995294619 45464.583256552796 54806.145405011055 47381.70221298895 49364.52363698816 59511.769757754664 46339.8665970649 39964.29249395133 1.2966030495083898 0.8893365819158509 1.4025870709816761 1.1376301297823286 1.3713778471946192 1.1856009266311986 1.2352157527737935 1.4891235661625157 1.159531764614087 1.0 15.286423928324126 -5.275195839208401 24.996771141793598 1.2629338998099309 1.0929697798099896 0.11972473893956881 0.1635951854603418 1213.8519781259204 2205681.8526687967 0.03948673293400763 0.08288984642917054 5.306451030565381e-06 5.275195839208401 -0.16996411999994132 INPYMS(ph)SPCHIEMILTEK ddPTM_PC-9_AZD4547_30min_R2 4 INPYMSSPCHIEMILTEK 18 0 A0A087WXM6;J3QQT2;J3KRX5;A0A0A6YYL6;P18621;P18621-3;J3QLC8;A0A0A0MRF8;P18621-2 A0A087WXM6 RPL17;RPL17-C18orf32 60S ribosomal protein L17 1 INPY(0.04)MS(0.568)S(0.393)PCHIEMILTEK;INPY(0.024)MS(0.787)S(0.188)PCHIEMILTEK;INPY(0.057)MS(0.472)S(0.472)PCHIEMILTEK;INPY(0.013)MS(0.558)S(0.428)PCHIEMILT(0.001)EK 78.531 0.0025151999999999996 26047600.0 142169.0 136112.0 212346.0 270164.0 226988.0 217084.0 171994.0 214650.0 177121.0 216825.0 True False 187375.78470109732 180107.5421847684 209530.15329558836 207881.8637921913 195474.6342980837 203509.70316271533 187301.13280347222 181480.77466629952 186483.2544603118 209234.022746394 0.8955321043949417 0.8607947207661877 1.001415307822826 0.9935375760765178 0.934239239547635 0.9726415450578181 0.8951753177851675 0.8673578621879611 0.8912664011929947 1.0 17.6747579362347 -9.742913250406717 12.41102400248746 0.9999999999991199 0.9253247586394194 0.18373757223345177 0.048209911843317986 0.0 0.0 0.05148857898147745 0.01248781468550523 1.807535142062091e-10 9.742913250406717 -0.0746752413597005 INPYMS(ph)SPCHIEMILTEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 INPYMSSPCHIEMILTEK 18 0 A0A087WXM6;J3QQT2;J3KRX5;A0A0A6YYL6;P18621;P18621-3;J3QLC8;A0A0A0MRF8;P18621-2 A0A087WXM6 RPL17;RPL17-C18orf32 60S ribosomal protein L17 1 INPY(0.116)MS(0.682)S(0.202)PCHIEMILT(0.001)EK 53.278 0.025061 15277000.0 45331.0 40033.0 57171.0 63970.0 78739.0 60174.0 61081.0 54463.0 52490.0 44853.0 True False 53004.64297193874 44007.21167112004 58534.17346222491 60385.96829353822 63310.658182640866 57018.36950972711 55294.965491855364 53033.40395831846 53257.566948676154 52984.49384384735 1.000380283487293 0.8305677468735552 1.1047415803335452 1.1396913306656102 1.194890308270683 1.0761331358145678 1.0436065626071147 1.0009231024196485 1.0051538305835965 1.0 15.693282589645985 -5.274269298491674 24.98319986371274 1.0768094326804265 0.9154740119506551 0.4284162572684187 0.07140828150629555 629.5549649949638 1225908.169258907 0.02005538480314351 0.0421719815107315 5.31778410422038e-06 5.274269298491674 -0.16133542072977136 INPYMS(ph)SPCHIEMILTEK ddPTM_PC-9_Lapatinib_30min_R1 2 INPYMSSPCHIEMILTEK 18 0 A0A087WXM6;J3QQT2;J3KRX5;A0A0A6YYL6;P18621;P18621-3;J3QLC8;A0A0A0MRF8;P18621-2 A0A087WXM6 RPL17;RPL17-C18orf32 60S ribosomal protein L17 1 INPY(0.045)MS(0.58)S(0.375)PCHIEMILTEK;INPY(0.003)MS(0.552)S(0.445)PCHIEMILTEK 89.87299999999999 0.0007913 22800200.0 117745.0 101719.0 142518.0 118125.0 130363.0 126338.0 119663.0 103387.0 135238.0 108001.0 True False 116065.93470821135 101483.4759050967 130800.72017538914 126812.30655344861 122695.30464351915 120934.81824826225 125858.56462444425 108190.7374527994 120006.07232072593 126668.82894771323 0.9162943691231362 0.8011716595800169 1.0326196370646283 1.0011326986041262 0.968630606778292 0.9547322672271812 0.9936032855912527 0.8541228205201038 0.9474001876993938 1.0 16.95070201978912 -5.258255956189243 24.999661826382965 0.9653195065887895 0.8587330166726513 0.4152928190245697 0.052201614880089495 274.2593763788007 2153753.2505761124 0.013813348824915347 0.03347347828926757 5.517521622832541e-06 5.258255956189243 -0.10658648991613817 INRLST(ph)PIAGLDNINVFLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 INRLSTPIAGLDNINVFLK 19 1 Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 Q8WWI1-3 LMO7 LIM domain only protein 7 1 INRLS(0.261)T(0.739)PIAGLDNINVFLK 106.69 0.00015615 1037600.0 8953.2 8694.2 9765.5 9643.3 12265.0 12846.0 13962.0 9080.1 9244.4 10295.0 True False 10468.799926239484 9557.30271803391 9998.346555864991 9103.017165000425 9861.761295039194 12172.333145909444 12639.418283873621 8841.756996161197 9379.581861313425 12161.402004824835 0.8608217968689926 0.7858717863484991 0.8221376574755372 0.7485170839175412 0.810906611846784 1.0008988388904727 1.0393060174196316 0.7270343495473117 0.7712582692022047 1.0 13.570021936358414 -6.5618387288540445 24.685759100133602 0.8996466793631542 0.8012172920010249 0.21635331459620244 0.09649314738179941 254.09033896975882 160994.47256380573 0.034303289975058215 0.034303338394447595 2.742592418598466e-07 6.5618387288540445 -0.09842938736212936 INSAPS(ph)SPIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 INSAPSSPIK 10 0 A0AVK6 A0AVK6 E2F8 Transcription factor E2F8 1 INSAPS(0.702)S(0.297)PIK;INS(0.001)APS(0.616)S(0.383)PIK 108.98 0.0019491 14188100.0 190685.0 209931.0 206533.0 202814.0 293340.0 243737.0 316380.0 278640.0 260649.0 236555.0 True False 222964.20429957734 230771.56229435484 211457.53000076435 191450.9891118601 235862.1327588091 230955.00264553414 286410.1960071572 271325.99524348427 264460.49852553813 279440.5489316507 0.7978949553026855 0.8258342004288004 0.7567174155977108 0.6851224342487523 0.8440512075307275 0.8264906561646649 1.0249414306626317 0.9709614309047496 0.9463927104946512 1.0 18.09218185630811 -7.072277115026336 2.5541274675793617 0.9835796459872788 0.777151695581912 0.8143256129512965 0.04593034888930068 0.1261912453160205 1.6209720828724468 0.02042139788552582 0.015542796207716163 8.466869869218609e-08 7.072277115026336 -0.20642795040536677 INSAPSS(ph)PIK ddPTM_PC-9_AZD4547_30min_R2 1 INSAPSSPIK 10 0 A0AVK6 A0AVK6 E2F8 Transcription factor E2F8 1 INSAPS(0.225)S(0.775)PIK 145.14 0.00013651 11701000.0 202860.0 216470.0 224700.0 242800.0 245610.0 252560.0 238030.0 266050.0 254960.0 238390.0 True False 267365.26024987514 286439.69419843063 221720.33118362838 186826.2112226058 211511.29103720142 236767.38327456263 259214.20887479006 224938.08572079637 268436.66508884396 230044.03866026894 1.162235117271274 1.24515156257297 0.9638168955600146 0.8121323739169455 0.9194382617737082 1.0292263370676724 1.1268025478269397 0.9778044544461633 1.1668925074179974 1.0 17.81155054549783 -5.263188523033157 24.973355989559888 0.9947765720461782 1.203693349499929 0.419675248270576 0.09591022873699272 143.28284369441283 2045756.4475848598 0.02708569596555946 0.06152820454389535 5.455210042958651e-06 5.263188523033157 0.2089167774537507 INSAPSS(ph)PIK ddPTM_PC-9_Lapatinib_30min_R1 2 INSAPSSPIK 10 0 A0AVK6 A0AVK6 E2F8 Transcription factor E2F8 1 INSAPS(0.218)S(0.782)PIK;INSAPS(0.226)S(0.774)PIK 140.45 0.00012306 21298000.0 129324.0 169057.0 180131.0 223420.0 317660.0 309490.0 291290.0 312680.0 313280.0 309860.0 True False 127479.81604488268 168665.5589033309 165321.32450576787 239851.0521072715 298975.8633435894 296253.8341564273 306371.57090708386 327208.2542944596 277995.1074153497 363418.88813750364 0.3507792803456304 0.46410785022135226 0.4549057022133002 0.6599851024158138 0.8226756316266878 0.8151855718746691 0.8430259981180854 0.9003611671682201 0.7649440259972594 1.0 18.47127387781226 -5.931520152243711 1.3222911567952358 0.8635116470725419 0.3872510293435063 0.9107178418554536 0.06136937780280179 0.11577874247565902 0.41063230604425405 0.02065439527599278 0.0412451262619387 1.1707922736570078e-06 5.931520152243711 -0.4762606177290356 INSAPSS(ph)PIKTNK ddPTM_PC-9_AZD4547_30min_R2 1 INSAPSSPIKTNK 13 1 A0AVK6 A0AVK6 E2F8 Transcription factor E2F8 1 INS(0.071)APS(0.221)S(0.708)PIKTNK 55.097 0.037143 19259000.0 66225.0 41638.0 59330.0 98648.0 92354.0 67732.0 69663.0 77985.0 60520.0 89111.0 True False 87283.17243442773 55096.66922453113 58543.245434466655 75906.227696407 79532.24124608014 63496.70733272381 75862.87204488709 65934.21016702244 63718.963645971235 85991.25101327765 1.015023870520858 0.6407241268768589 0.6808046719244399 0.8827203558730242 0.9248875938995214 0.7384089263094855 0.882216169098102 0.7667548662228642 0.7409935649864261 1.0 16.39190226306372 -10.564077205868 4.601566077347409 1.0000071210680999 0.8039446809334242 0.21161803267220214 0.1108868417992534 155378356.34957275 0.6030792704275751 12499.79994345822 0.026578141590617617 2.728492687140055e-11 10.564077205868 -0.19606244013467566 INSAPSS(ph)PIKTNK ddPTM_PC-9_Lapatinib_30min_R1 1 INSAPSSPIKTNK 13 1 A0AVK6 A0AVK6 E2F8 Transcription factor E2F8 1 INS(0.001)APS(0.086)S(0.913)PIKTNK 87.99 0.0032203 8775500.0 58570.0 26708.0 36934.0 44965.0 51436.0 50026.0 43616.0 38212.0 68663.0 45712.0 True False 57734.78105957745 26646.159266934636 33897.429089362915 48271.8760988428 48410.63560706683 47886.504596301726 45874.22306527299 39987.469019764336 60929.449886555565 53613.258292588675 1.076875065949098 0.4970068993291929 0.6322583287956738 0.9003719907378908 0.9029601473365212 0.8931840018930803 0.8556507201058231 0.7458503790524531 1.1364623570169816 1.0 15.710302195674364 -7.3442842041721885 0.43835305696009796 1.0183889766989198 0.7337647294169077 0.18134473279371988 0.16785294135705983 1.8649785638874865 0.8304074701298636 0.1789241017532205 0.17906720618549968 4.52601298738695e-08 7.3442842041721885 -0.2846242472820121 INSS(ph)PNVNTTASGVEDLNIIQVTIPDDDNER ddPTM_PC-9_AZD4547_30min_R2 1 INSSPNVNTTASGVEDLNIIQVTIPDDDNER 31 0 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347 A0A494C1K3 GTF2I General transcription factor II-I 1 INS(0.067)S(0.407)PNVNT(0.407)T(0.11)AS(0.009)GVEDLNIIQVTIPDDDNER 80.245 3.7943000000000006e-07 2395000.0 4497.1 5245.9 7770.3 8040.8 6922.5 6762.5 6690.1 8054.2 5742.7 8379.9 True False 5927.084254509094 6941.534585834282 7667.260744976172 6187.117789121621 5961.430366047913 6339.639805963861 7285.505939559003 6809.608457103712 6046.24739804559 8086.522251643051 0.7329583806320208 0.8584079001852587 0.9481530510125422 0.7651147918209832 0.7372057085277476 0.7839760540664744 0.9009442765187106 0.8420935780792675 0.747694399383751 1.0 12.981303664814483 -11.31530171171639 6.650843935048012 1.0076096034535031 0.8172217582616621 0.3918068818359751 0.06973142809989351 0.00845060453849514 0.00026374841546307904 0.07251582132764128 0.017113428098529258 4.838361216689465e-12 11.31530171171639 -0.19038784519184104 INSS(ph)PNVNTTASGVEDLNIIQVTIPDDDNER ddPTM_PC-9_Lapatinib_30min_R1 1 INSSPNVNTTASGVEDLNIIQVTIPDDDNER 31 0 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347 A0A494C1K3 GTF2I General transcription factor II-I 1 INS(0.188)S(0.645)PNVNT(0.095)T(0.035)AS(0.035)GVEDLNIIQVT(0.001)IPDDDNER 46.15 0.010506 3319500.0 1240.6 2678.3 3552.2 2469.6 2799.8 1497.5 3140.1 1510.2 4134.4 2719.2 True False 1222.9088165018231 2672.0985609042627 3260.15182788853 2651.2226223440935 2635.121268618589 1433.4554158429985 3302.679013372699 1580.369405256152 3668.7403348379116 3189.210096893752 0.3834519455751504 0.8378559203443043 1.022244295245357 0.8313101181155638 0.8262614216558395 0.44947036171720545 1.0355790032740284 0.49553631063548015 1.150360190572335 1.0 11.638983426392302 -8.284340208134138 24.853046202597668 1.0751801817978313 0.7549282924741275 0.27559114522597505 0.21861149223600954 1156.2019982977772 1254751.0854526204 0.20275539968693698 0.05249725565778723 5.195888129231381e-09 8.284340208134138 -0.32025188932370374 INSSGES(ph)GDESDEFLQSR ddPTM_PC-9_AZD4547_30min_R2 2 INSSGESGDESDEFLQSR 18 0 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 INS(0.049)S(0.025)GES(0.926)GDESDEFLQSR;INSSGES(1)GDESDEFLQSR 184.6 4.4992e-25 1509200.0 4055.05 5007.1 7212.0 8311.5 8613.9 6869.8 6160.6 7556.6 6347.900000000001 8052.3 True False 5344.471549720281 6625.547155822805 7116.364167762915 6395.41208639493 7418.008671737102 6440.230320001561 6708.881465336421 6388.901103393252 6683.4370345053 7770.391427929371 0.687799527126841 0.8526658170666132 0.915830847617835 0.823048896019278 0.9546505784862153 0.8288167178880116 0.8633904131550528 0.8222109738808545 0.860115876593141 1.0 12.92377155985992 INSSGES(ph)GDESDEFLQSR ddPTM_PC-9_Lapatinib_30min_R1 2 INSSGESGDESDEFLQSR 18 0 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 INS(0.045)S(0.154)GES(0.798)GDES(0.002)DEFLQSR;INSSGES(0.997)GDES(0.003)DEFLQSR 261.94 2.9390999999999997e-66 4301900.0 14111.599999999999 12373.1 12876.5 11541.7 10420.0 7825.5 3983.1000000000004 5317.4 6585.9 2253.1 True False 13910.365996249497 12344.450847151003 11817.843874727401 12390.515119982523 9807.116086508215 7490.8216071314755 4189.325428542022 5564.465816123071 5844.126589398463 2642.545332932962 5.2640027865899945 4.671424438138169 4.472144234366179 4.688856219632109 3.7112385412224103 2.8346993763082997 1.5853372036165934 2.1057219896194055 2.211552065565537 1.0 11.367712505952765 -6.729988877730677 1.2722995749496457 1.739619363768397 4.838636163777356 0.9328425773112718 0.3687456664872949 0.10478446296871896 0.35679416830736754 0.17643228808160086 0.16379523806658872 1.8621348252720977e-07 6.729988877730677 3.0990168000089593 INSSPNVNT(ph)TASGVEDLNIIQVTIPDDDNER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 INSSPNVNTTASGVEDLNIIQVTIPDDDNER 31 0 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347 A0A494C1K3 GTF2I General transcription factor II-I 1 INS(0.009)S(0.091)PNVNT(0.828)T(0.071)AS(0.002)GVEDLNIIQVTIPDDDNER 105.53 7.460200000000001e-15 2001500.0 3923.4 4470.4 3289.0 6734.3 6686.5 5295.8 4328.4 3956.9 3344.5 2729.6 True False 4587.554129317786 4914.191768155643 3367.4222336019616 6356.999003895178 5376.328324441874 5018.078925276913 3918.3826170977363 3853.0355676821027 3393.40698532763 3224.454872498288 1.4227378923629894 1.5240380040884733 1.0443384592921605 1.9714957272668587 1.6673603871144669 1.5562565220176072 1.2152077706275348 1.1949416940348725 1.0523971088168584 1.0 11.654839563269725 -7.439263987315695 2.449497896406817 1.090016702088522 1.5358244221176771 0.4671752663970645 0.22014831976503751 0.29726645994576145 3.496388733416253 0.1201919990261848 0.06946545982152091 3.636938964039727e-08 7.439263987315695 0.44580772002915503 INVYYNEATGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 INVYYNEATGGK 12 0 P68371 P68371 TUBB4B Tubulin beta-4B chain 0 106.16 0.0078549 6379900.0 27340.0 38090.0 35625.0 32826.0 39613.0 39933.0 40533.0 36820.0 31751.0 27224.0 False True 31968.122010385952 41871.32347195969 36474.43510856488 30986.865643327903 31851.117014299823 37838.84318197118 36693.4208064926 35853.51401401478 32215.298308009464 32159.495694934594 0.9940492324144627 1.301989430094042 1.134173105653206 0.9635370509932657 0.990410960309824 1.1765993951183484 1.1409824692080646 1.114865554924172 1.0017351830888213 1.0 14.972957162803807 -8.352712672774121 0.012802666316925797 9.767489052839095e-07 2.13299845383866 0.07591647296811976 0.0998768845384515 2189.0455588435784 21.9832859167278 1851.1236821563602 1806.8324660205221 4.439022304709854e-09 8.352712672774121 2.132997477089755 INVYYNEATGGK ddPTM_PC-9_Lapatinib_30min_R1 2 INVYYNEATGGK 12 0 P68371 P68371 TUBB4B Tubulin beta-4B chain 0 ; 186.46 0.001726 39112000.0 145904.0 136145.0 158388.0 133657.0 164313.0 149360.0 151396.0 138070.0 140644.0 147055.0 False True 143823.38220448326 135829.7646172238 145365.95003536067 143486.58164668156 154648.4323917873 142972.22097516546 159234.54409368284 144485.23624931587 124803.19167302217 172473.26081152965 0.833887998219309 0.7875410018811665 0.8428318068051689 0.8319352285191424 0.8966516413276349 0.8289529652448475 0.9232419178743687 0.8377254281010102 0.7236089297888384 1.0 17.39601318714049 -5.705655264701141 2.020566518302291 0.8605257118974305 0.812113181960881 0.08492596700185673 0.06841057374719323 0.9257925150881304 7.677458538509917 0.020178767075958847 0.042014905762141896 1.969448983267695e-06 5.705655264701141 -0.04841252993654954 IPAKLSPT(ph)QLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IPAKLSPTQLR 11 1 Q9UNS1-2;Q9UNS1 Q9UNS1-2 TIMELESS Protein timeless homolog 1 IPAKLS(0.014)PT(0.986)QLR 65.278 0.032505 21904000.0 74511.0 82960.0 90922.0 91087.0 96482.0 87081.0 92091.0 100630.0 96011.0 61221.0 True False 87124.24064066798 91195.72053646053 93089.9253036053 85983.69069803854 77577.04470183233 82514.31906266074 83367.47379889755 97988.56912629858 97414.9792400334 72319.8826748307 1.2047066092792431 1.2610048186402705 1.2871968518279018 1.1889357050625196 1.0726931769322583 1.1409631212161517 1.1527600808444303 1.3549326340431314 1.347001345093947 1.0 16.142104716807843 -11.820203779847885 2.209864184768522 1.7201488025860365e-05 1.220266748711044 0.376589296489644 0.08612997829990067 4486208.158850922 289399.90143268224 22695550.34779238 0.025495067499505066 1.5128512211539446e-12 11.820203779847885 1.2202495472230181 IPALS(ph)PSSGK ddPTM_PC-9_AZD4547_30min_R2 1 IPALSPSSGK 10 0 Q5T5P2;Q5T5P2-2;Q5T5P2-7;Q5T5P2-10;Q5T5P2-9 Q5T5P2;Q5T5P2-9 KIAA1217 Sickle tail protein homolog 1 IPALS(0.7)PS(0.222)S(0.078)GK 67.385 0.043733999999999995 5461300.0 29536.0 28739.0 36194.0 53534.0 38477.0 37471.0 35501.0 37848.0 37997.0 39908.0 True False 38927.83361303517 38028.31972822424 35714.04391126051 41192.56339205512 33135.13271136516 35127.93244647275 38660.520225450186 31999.46126051766 40005.44384758707 38510.833067049796 1.0108281362093452 0.9874707114752498 0.9273765604883203 1.0696357391266051 0.8604106967427787 0.9121571684858854 1.0038868844550772 0.8309210347333845 1.0388101389013076 1.0 15.232976711427584 -6.263133878005182 24.998114831666424 0.9342761462786984 0.9929129048661013 0.13860760632899372 0.06874027364145098 295.89244661846766 4365153.791152627 0.01985671651018878 0.023723916194044632 5.455896487002521e-07 6.263133878005182 0.058636758587402915 IPALS(ph)PSSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IPALSPSSGK 10 0 Q5T5P2;Q5T5P2-2;Q5T5P2-7;Q5T5P2-10;Q5T5P2-9 Q5T5P2;Q5T5P2-9 KIAA1217 Sickle tail protein homolog 1 IPALS(0.958)PS(0.021)S(0.021)GK 77.062 0.022281 3353600.0 24400.0 22615.0 25399.0 39421.0 29923.0 31123.0 33748.0 33219.0 27240.0 25237.0 True False 28530.438078032796 24860.067742671785 26004.608486243895 37212.36917460641 24059.802954052808 29490.85509108979 30551.14512563867 32347.036448439892 27638.333466983015 29812.268324017925 0.957003263486917 0.8338871592217472 0.8722787613344258 1.2482233411480022 0.8070436872684824 0.9892187595578162 1.0247843201191598 1.0850243294764612 0.9270791865480593 1.0 14.86361852929354 IPAVTLAVTS(ph)VAGSPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IPAVTLAVTSVAGSPAR 17 0 Q9Y4B5 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 IPAVT(0.001)LAVT(0.191)S(0.568)VAGS(0.24)PAR 94.61 0.012896000000000001 0.0 647.2 557.45 713.46 738.22 1026.7 2068.5 1140.1 879.87 1032.5 749.78 True False 756.7581772173295 612.7899519412948 730.4715922121175 696.8599267415323 825.5255052276178 1960.0242186138637 1032.1014743907974 856.7743447993262 1047.5983592019077 885.7091787447862 0.8544093200996244 0.6918636123989723 0.8247307465497093 0.7867818731754725 0.9320502993968519 2.2129433290863947 1.1652825771247806 0.9673314507291592 1.182779160860169 1.0 9.790689259596627 -6.541118673710848 24.99993685552941 1.3257009390574808 0.7942986648000602 0.3598608781770426 0.3290833299753125 271.06280967402483 371520.4783169317 0.11227994468741133 0.11229809442760982 2.8766122548572635e-07 6.541118673710848 -0.5314022742574206 IPAVTLAVTSVAGS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 1 IPAVTLAVTSVAGSPAR 17 0 Q9Y4B5 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 IPAVTLAVT(0.044)S(0.035)VAGS(0.921)PAR 65.652 0.021196 2324300.0 2913.8 1146.1 3178.8 3426.5 3356.4 3533.9 1531.7 3541.9 2969.2 3174.3 True False 3840.327789194946 1516.5544117929571 3136.647035008977 2636.573363897276 2890.4217956812154 3312.924674350568 1668.0183327039235 2994.5807397650483 3126.145850258061 3063.1687231817255 1.253710825698815 0.49509333270343203 1.0239876802316423 0.8607339660868099 0.9436051542988213 1.0815351597444556 0.5445401423958607 0.9776088130903104 1.0205594705246666 1.0 11.580809119242968 -7.978233949712146 24.995408490563676 1.006548405137692 0.8763115755773493 0.054530881405423615 0.21604746172485922 638.9160411033818 733709.6496032603 0.11142483401576524 0.053520308234941014 1.051395346012342e-08 7.978233949712146 -0.13023682956034277 IPCDS(ph)PQSDPVDTPTSTK ddPTM_PC-9_AZD4547_30min_R2 2 IPCDSPQSDPVDTPTSTK 18 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IPCDS(0.996)PQS(0.004)DPVDTPTSTK;IPCDS(1)PQSDPVDTPTSTK 140.96 4.1666000000000004e-05 16921000.0 45250.0 81178.0 71705.0 102766.0 85328.0 53742.0 40463.0 58801.0 44235.0 60084.0 True False 59638.558741530396 107417.20097768851 70754.14484878533 79074.88641887273 73481.68006849206 50381.50424430464 44064.128612782435 49714.65656255811 46573.17179245764 57980.47744814626 1.0285972342133094 1.8526442986564753 1.2203098001747736 1.3638191663666768 1.2673521037181696 0.8689391060872581 0.7599821621370806 0.8574378609941505 0.8032560931239221 1.0 15.823279593066676 -6.697194189463802 3.074841533143923 0.8358970848681654 1.3861528848398539 0.5954804891986225 0.20207962036084703 0.1629167816620998 3.123203855641557 0.06915357050450525 0.06676487354373296 2.0081946721509146e-07 6.697194189463802 0.5502557999716885 IPCDS(ph)PQSDPVDTPTSTK ddPTM_PC-9_Lapatinib_30min_R1 1 IPCDSPQSDPVDTPTSTK 18 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IPCDS(0.631)PQS(0.369)DPVDTPTSTK 89.507 0.0014333 5730900.0 13126.0 24258.0 14718.0 8573.9 8673.0 12887.0 21839.0 20115.0 11295.0 8566.3 True False 12938.820832986397 24201.832091407065 13507.942853122973 9204.453207691948 8162.871191774063 12335.853051064267 22969.716560952307 21049.616333417765 10022.838158377077 10046.973541122743 1.2878326771765831 2.4088679035878626 1.3444787923282884 0.9161418779513731 0.8124706567966006 1.227817810067184 2.2862324128690257 2.095120112266712 0.9975977459633114 1.0 13.294473362070724 IPCES(ph)PPLEVVDTTASTK ddPTM_PC-9_AZD4547_30min_R2 2 IPCESPPLEVVDTTASTK 18 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IPCES(1)PPLEVVDTTASTK;IPCES(0.997)PPLEVVDT(0.002)T(0.002)ASTK 105.02 0.00035221 29761000.0 46331.0 100274.0 73873.0 90585.0 58588.0 66092.0 50380.0 75719.0 48099.0 64620.0 True False 61063.29425533362 132685.6095350553 72893.39575223932 69702.02777429874 50454.06750249405 61959.25679197979 54863.722401007835 64018.368399522784 50641.41494394531 62357.67346879718 0.9792426634692962 2.127815265613608 1.1689563079789058 1.1177778755517003 0.8091075996884408 0.9936107834905555 0.8798231131644255 1.0266317654002373 0.8121120004466731 1.0 15.92827948241449 -5.493394704631554 9.159792175188851 0.9577496327788795 1.5779426165205621 0.43577998084275216 0.27269941687386084 0.30357312156291405 89.54935077666592 0.06642760769778037 0.13426629762403194 3.2107411590072023e-06 5.493394704631554 0.6201929837416826 IPCES(ph)PPLEVVDTTASTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 IPCESPPLEVVDTTASTK 18 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IPCES(1)PPLEVVDTTASTK;IPCES(1)PPLEVVDTTASTK;IPCES(1)PPLEVVDTTASTK;IPCES(1)PPLEVVDTTASTK;IPCES(1)PPLEVVDTTASTK 161.99 2.7968e-06 20657800.0 104143.2 145928.3 118342.4 139133.2 175074.0 92758.9 136733.0 119133.3 109695.9 67205.5 True False 121772.58683804017 160415.09721746307 121164.13163205142 131338.01787992037 140769.50647922506 87894.45999128908 123780.66037880609 116006.17710716545 111299.99501324628 79389.32515155479 1.533866002835714 2.02061293393324 1.5262018086279008 1.6543536253670774 1.773154088543958 1.1071319704947478 1.5591600022107244 1.4612314298642648 1.4019516452718774 1.0 16.27665741227962 -9.596917087763705 0.07890878427330705 1.5478469710312706e-12 2.4630404832415547 0.5056166728607467 0.19764279552806657 43.35793887872316 1.029157870731873 20.4857412979002 11.405035324587512 2.529780917093906e-10 9.596917087763705 2.463040483240007 IPCES(ph)PPLEVVDTTASTK ddPTM_PC-9_Lapatinib_30min_R1 3 IPCESPPLEVVDTTASTK 18 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IPCES(1)PPLEVVDTTASTK;IPCES(0.999)PPLEVVDTTASTK;IPCES(1)PPLEVVDTTASTK 118.72 9.658799999999999e-05 13210300.0 32044.6 83072.4 64830.4 32761.5 43072.1 58765.4 96703.5 84155.2 46900.8 34908.7 True False 31587.63812774007 82880.05096175314 59500.29476458099 35170.88999916022 40538.68376100673 56252.14083083821 101710.3340561405 88065.35781566189 41618.33801668099 40942.62228208111 0.7715098927985536 2.024297574071759 1.4532604764453938 0.8590287587552267 0.9901340339587588 1.3739261848759854 2.4842164079132494 2.1509457115111177 1.0165039681616976 1.0 15.321315886214643 -7.021069997114418 24.583312030658842 1.7831490740560205 1.2497668929901589 0.1141281128755155 0.5401814183612603 1137.4645870218608 1327127.7870631563 0.20696446939169286 0.16215447467395272 9.526426101320407e-08 7.021069997114418 -0.5333821810658617 IPCES(ph)PPLEVVDTTASTKR ddPTM_PC-9_AZD4547_30min_R2 1 IPCESPPLEVVDTTASTKR 19 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IPCES(1)PPLEVVDTTASTKR 116.45 3.1039e-05 17570000.0 25454.0 34723.0 41811.0 74788.0 59541.0 33722.0 26530.0 36965.0 17792.0 37419.0 True False 33547.84252390972 45946.53070472631 41256.55882117793 57546.782063081744 51274.759902471465 31613.358009125845 28891.11860457994 31252.908621196228 18732.448796912093 36108.972199457196 0.9290722078324352 1.2724408341209168 1.1425569964519267 1.5936975925320525 1.420000536687728 0.8754986941888384 0.8001091375570707 0.8655164275671638 0.5187754637113068 1.0 15.14006973575821 -6.857554227538818 5.555338999719264 0.7933207493222748 1.28113618893098 0.5790371373618872 0.1963814108513055 0.15455802965056167 7.288309949937593 0.07204904307753812 0.06370398988980908 1.388179966066663e-07 6.857554227538818 0.4878154396087052 IPCES(ph)PPLEVVDTTASTKR ddPTM_PC-9_Lapatinib_30min_R1 1 IPCESPPLEVVDTTASTKR 19 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IPCES(1)PPLEVVDTTASTKR 105.02 0.00011378 12490000.0 51732.0 51459.0 49599.0 23752.0 22260.0 33283.0 42090.0 30033.0 29916.0 11949.0 True False 50994.29219351306 51339.84984713154 45521.16167767673 25498.801314349275 20950.71056484384 31859.56367646246 44269.21425204833 31428.442820856853 26546.545050554127 14014.368728958307 3.6387148918197103 3.6633722745603574 3.2481778207829657 1.819475554518581 1.4949450075159478 2.273349894856848 3.158844690633374 2.242587121024961 1.894237661643668 1.0 13.774619139823335 -1.5228787453843637 0.34605315720835 1.8713207973321966 26.162470517093574 0.5416627242746064 0.5986706806416463 54.1415943827474 0.7643040723344975 0.5651355301969457 854.8222820469542 0.029999999992814125 1.5228787453843637 24.29114971976138 IPCKS(ph)PPPELTDTATSTK ddPTM_PC-9_AZD4547_30min_R2 1 IPCKSPPPELTDTATSTK 18 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IPCKS(0.998)PPPELT(0.002)DTATSTK 77.795 0.0022509 19347000.0 34486.0 47905.0 42772.0 48784.0 40711.0 44174.0 27037.0 41030.0 33557.0 43739.0 True False 45451.83064663903 63389.35441666663 42204.81533327168 37537.60250528665 35058.98037301214 41411.79279684255 29443.2406223908 34689.75627560344 35330.75451202671 42207.71092311548 1.0768608307006498 1.5018429815380205 0.9999313966623522 0.8893541413241817 0.8306297500206706 0.9811428265389053 0.6975796596982925 0.8218819622507706 0.837068718945321 1.0 15.365218968394458 -5.473914797242232 4.660589650640303 0.8586935832700916 1.289089461338819 0.641459017128635 0.12496367371629719 0.1129195705276001 5.331239598437257 0.03175735931387511 0.06630394779904325 3.3580348792551342e-06 5.473914797242232 0.4303958780687275 IPCKS(ph)PPPELTDTATSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IPCKSPPPELTDTATSTK 18 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IPCKS(1)PPPELTDTATSTK 76.76100000000001 0.0024715999999999996 8900300.0 34255.0 39118.0 32651.0 39257.0 38578.0 28199.0 36927.0 27405.0 26209.0 22984.0 True False 40053.69493291039 43001.37651814434 33429.523669607064 37057.55756291122 31018.917834490167 26720.194798497625 33429.00723167176 26685.64778799767 26592.257042443372 27150.81725875612 1.475229808045395 1.5837967641388924 1.2312529435490958 1.3648781622203354 1.1424671875940156 0.9841396133252814 1.2312339224665854 0.982867201884745 0.9794274989592583 1.0 14.728708004371322 -5.688897022251506 0.5640397469320888 1.0008339683878515 1.655723315232887 0.7840752448480475 0.09723105755627276 0.7340078867786902 0.3527830692373292 0.06263395635749738 0.28094033672150864 2.0469299370369475e-06 5.688897022251506 0.6548893468450354 IPCKS(ph)PPPELTDTATSTK ddPTM_PC-9_Lapatinib_30min_R1 1 IPCKSPPPELTDTATSTK 18 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IPCKS(1)PPPELTDTATSTK 129.2 1.9853e-05 12345000.0 28770.0 34428.0 32181.0 23287.0 27004.0 23798.0 30516.0 29662.0 19405.0 15968.0 True False 28359.73452422815 34348.28408125 29535.202402252355 24999.60366315474 25415.677811906677 22780.215015847538 32095.96916406526 31040.204806454793 17219.40455629104 18728.047523977428 1.5142921058866026 1.8340557945121647 1.5770572113531098 1.3348750653877757 1.357091697859433 1.2163689240259636 1.7137915270117159 1.6574180926609765 0.9194447277136135 1.0 14.192912880075253 -10.721917390024908 0.076686816556557 5.834744498333686e-11 2.1774420684929363 0.3808605876910244 0.22624406610695846 114.65589726498992 1.596175530644385 34.926600729514284 13.378355198746833 1.8970667402834413e-11 10.721917390024908 2.1774420684345888 IPCKS(ph)SPELEDTATSSK ddPTM_PC-9_AZD4547_30min_R2 2 IPCKSSPELEDTATSSK 17 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IPCKS(0.968)S(0.032)PELEDTATSSK;IPCKS(0.5)S(0.5)PELEDTATSSK 124.2 1.9352e-05 92546000.0 63877.0 92275.0 88270.0 113206.0 93766.0 76526.0 57458.0 54929.0 44672.0 75483.0 True False 84188.55727586162 122101.08921402588 87099.4821254065 87108.10571526499 80748.20941897412 71740.81712254221 62571.650689104994 46440.98519284967 47033.27072030451 72840.36314523725 1.1557954084879707 1.6762833673765065 1.195758482858437 1.1958768731229295 1.1085640698683685 0.9849047152537853 0.8590244198033808 0.6375721260511902 0.6457034079652283 1.0 16.152450494430468 -6.597831718646861 0.8772427742603768 0.7342449409116367 1.3908489864554547 0.6751513578942329 0.16380392767677307 0.31829214565595115 0.5383113745626331 0.09384804846719882 0.10445941497878371 2.524458765663552e-07 6.597831718646861 0.656604045543818 IPCKS(ph)SPELEDTATSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IPCKSSPELEDTATSSK 17 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IPCKS(0.836)S(0.164)PELEDTATSSK;IPCKS(0.5)S(0.5)PELEDTATSSK 100.67 0.00053633 59331000.0 133107.0 129385.0 122163.0 224580.0 192459.0 159312.0 212943.0 194444.0 153027.0 116898.0 True False 155639.38611691463 142229.4877243243 125075.82922575773 211997.5106981838 154748.04052849163 150957.39826725234 192771.49746618693 189340.05103044747 155264.73037635887 138090.682035941 1.127081015331695 1.0299716507106982 0.9057514046690285 1.535205037534734 1.1206262308720818 1.0931758467813384 1.3959775896828008 1.3711283646290324 1.1243679014920642 1.0 17.075256448384145 -5.725753957525502 24.999993854570786 1.2459318994081172 1.0218384251447443 0.2664187650665386 0.16148741340510755 228.36007857525664 159979.70259655072 0.04308859539657174 0.07462827590112055 1.8803818148270732e-06 5.725753957525502 -0.2240934742633729 IPCKS(ph)SPELEDTATSSK ddPTM_PC-9_Lapatinib_30min_R1 2 IPCKSSPELEDTATSSK 17 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IPCKS(0.499)S(0.499)PELEDT(0.001)ATSSK;IPCKS(0.499)S(0.499)PELEDT(0.001)ATSSK 71.697 0.0061426 57216000.0 108753.0 132907.0 92646.0 48866.0 51168.0 56076.0 124657.0 111652.0 61137.0 26291.0 True False 107202.16227714227 132599.26200728177 85029.00350390187 52459.768652197345 48158.39884015857 53677.76019954056 131111.12950861442 116839.75952566527 54251.107258849006 30835.364319444547 3.4765978817880026 4.300233350045606 2.7575157738701734 1.7012858388417553 1.5617911415364807 1.740785665557769 4.251972772247634 3.7891480157407127 1.7593794805478808 1.0 14.912298271389977 -8.493151613986832 6.08353661804606 1.001419653977668 2.898487937049459 0.3063015167957627 0.9750846524548428 0.22083635826832232 26.820227373843544 1.0611705770246649 0.2750134903183758 3.2125388323586134e-09 8.493151613986832 1.897068283071791 IPCKSS(ph)PELEDTATSSK ddPTM_PC-9_AZD4547_30min_R2 2 IPCKSSPELEDTATSSK 17 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IPCKS(0.161)S(0.838)PELEDTATSSK;IPCKS(0.382)S(0.618)PELEDTATSSK 90.22 0.0011432 98391000.0 79379.0 121138.0 103541.0 131742.0 104075.0 98117.0 70348.0 79534.0 72977.0 87295.0 True False 104619.87081423064 160293.48951729786 102167.97868751243 101370.91729361014 89625.98271526718 91981.72847937234 76608.83571786602 67243.84780950133 76834.41523450174 84238.8286205301 1.2419435612704308 1.9028456608694135 1.2128371246441187 1.2033752006483234 1.0639509616047078 1.0919160437726598 0.9094242758641049 0.7982524081906942 0.912102132623627 1.0 16.362197754717663 -5.9308830422827645 0.9251919943036855 0.9095046421906301 1.5866586778030771 0.6191729999653057 0.18000590571000802 0.3977901878160913 0.6743556404478221 0.07612645718042911 0.18775213942819335 1.1725110862445227e-06 5.9308830422827645 0.677154035612447 IPCKSS(ph)PELEDTATSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IPCKSSPELEDTATSSK 17 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 IPCKS(0.108)S(0.892)PELEDTATSSK 141.31 4.6082e-05 18885000.0 31940.0 26604.0 18593.0 35634.0 38112.0 26323.0 41414.0 33616.0 27459.0 17777.0 True False 37346.81115624458 29245.06930028918 19036.32763434516 33637.54250698673 30644.227189281166 24942.57554100687 37490.96610860495 32733.615619096152 27860.535927675708 20999.82937734544 1.7784340284466416 1.392633662625787 0.9064991573160829 1.6018007528801552 1.4592607701060694 1.1877513427759017 1.7852986057615359 1.5587562656299052 1.3267029663456018 1.0 14.358089985657152 IPDWFLNR ddPTM_PC-9_Lapatinib_30min_R1 2 IPDWFLNR 8 0 P62269;J3JS69 P62269 RPS18 40S ribosomal protein S18 0 ; 133.6 0.016172 11149500.0 21070.8 20996.7 19033.8 19153.0 18534.6 19605.2 18253.2 18750.2 19734.1 16584.9 False True 20770.32652808853 20948.083431183393 17468.914436592746 20561.575512534997 17444.431268425622 18766.731297953364 19198.261382406465 19621.402742970422 17511.437848714406 19451.577867009848 1.0677964877756936 1.0769349188227881 0.8980718456892011 1.0570646583590384 0.8968131730851319 0.96479223568706 0.9869770726912076 1.0087306478231053 0.9002579620244614 1.0 14.247599567592815 -5.236944026172597 24.472607746542902 0.9661607349076986 1.0723657546960033 0.42352268771546153 0.050483783983764165 540.9105374663424 540405.5980190501 0.012001210667415173 0.031716319058386164 5.795033806177536e-06 5.236944026172597 0.10620501978830466 IPEISIQDMTAQVT(ph)SPSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IPEISIQDMTAQVTSPSGK 19 0 Q60FE5;P21333-2;P21333 Q60FE5 FLNA Filamin-A 1 IPEISIQDMT(0.076)AQVT(0.916)S(0.007)PS(0.001)GK 86.699 0.0059878 0.0 13256.0 17529.0 24327.0 20362.0 25442.0 18446.0 20958.0 16926.0 16327.0 12988.0 True False 15499.978982065695 19269.163274874794 24907.047940661272 19221.183154494684 20456.82273692517 17478.65928767287 18972.706517219824 16481.710434579407 16565.751487350655 15342.621587048576 1.010256226038316 1.255923778446103 1.6233893144888925 1.252796534506214 1.3333329392803202 1.139222471759808 1.2366013467499957 1.0742434297207974 1.0797210498455219 1.0 13.905257396124886 -7.603833011123609 0.9206767262641782 1.0178719973619434 1.3054441552599116 0.319244210095044 0.1462663608683461 0.716723413581131 1.1134928178360208 0.13120001697993064 0.05986378813904251 2.4898144831030723e-08 7.603833011123609 0.2875721578979682 IPEISIQDMTAQVTS(ph)PSGK ddPTM_PC-9_AZD4547_30min_R2 1 IPEISIQDMTAQVTSPSGK 19 0 Q60FE5;P21333-2;P21333 Q60FE5 FLNA Filamin-A 1 IPEISIQDMTAQVT(0.44)S(0.552)PS(0.008)GK 123.55 2.5879e-05 3860900.0 11284.0 8709.1 10799.0 11498.0 11602.0 12305.0 13707.0 13383.0 12101.0 12089.0 True False 14872.077278219422 11524.14625926711 10655.798204058743 8847.31374232917 9991.262565097559 11535.566404788962 14926.896446022514 11314.96486074582 12740.634155318867 11665.767789605221 1.2748477036780368 0.9878600763453991 0.9134245080339752 0.7583996100293172 0.8564599214807165 0.9888390213859499 1.279546851543121 0.9699288606471335 1.0921385017342284 1.0 13.509993641848293 -7.01450325724391 24.361357046451747 1.0902255314248233 0.9438979160268166 0.14272737727814166 0.14591170060299527 901.1149796181357 1513615.9353320533 0.05700289990482065 0.045917609947544374 9.671564728706678e-08 7.01450325724391 -0.14632761539800665 IPEISIQDMTAQVTS(ph)PSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IPEISIQDMTAQVTSPSGK 19 0 Q60FE5;P21333-2;P21333 Q60FE5 FLNA Filamin-A 1 IPEISIQDMT(0.002)AQVT(0.066)S(0.681)PS(0.25)GK 64.89 0.0096617 6562000.0 16988.0 32340.0 22559.0 21600.0 28185.0 15195.0 19053.0 18550.0 14401.0 13767.0 True False 19863.732871705797 35550.501472385804 23096.892115483908 20389.82202814485 22662.351577715424 14398.147450731278 17248.161908225484 18063.08215534964 14611.587380984667 16262.848120487972 1.2214178429595872 2.185994802939788 1.4202243016945102 1.2537669833156535 1.3935044716531138 0.8853398460133475 1.0605867914671239 1.1106961106396689 0.8984642341077365 1.0 13.989292318972227 -6.049251702515719 1.111076095976699 1.008389150798564 1.705286173164585 0.5088783255306035 0.2527098094239524 0.39207524478234945 0.9896884054327437 0.0977388176605602 0.18599149969852904 8.927879038363474e-07 6.049251702515719 0.6968970223660209 IPEISIQDMTAQVTS(ph)PSGK ddPTM_PC-9_Lapatinib_30min_R1 1 IPEISIQDMTAQVTSPSGK 19 0 Q60FE5;P21333-2;P21333 Q60FE5 FLNA Filamin-A 1 IPEISIQDMTAQVT(0.011)S(0.753)PS(0.236)GK 147.6 3.4286e-14 0.0 3678.0 8253.8 10350.0 9808.7 12317.0 8730.8 12023.0 10332.0 9737.3 11914.0 True False 3625.551045537406 8234.688833211962 9499.062952155366 10530.064518864 11592.538276153713 8357.404036488857 12645.492111009191 10812.0624388204 8640.582735685275 13973.319025592884 0.2594624111062672 0.5893151668640562 0.6798000485609269 0.7535836331781748 0.8296195238168796 0.5980972753274882 0.9049741215990484 0.7737648026941578 0.6183629472611041 1.0 13.77038711848156 -4.70518047964578 1.3028854101154064 0.7717587261923851 1.604865613698761e-16 0.6576415172902854 0.1141953972411796 0.9728123109433848 1.283129086931934 0.03205320947608814 1.0534758708417158 1.971603227200713e-05 4.70518047964578 -0.771758726192385 IPEISIQDMTAQVTSPS(ph)GK ddPTM_PC-9_AZD4547_30min_R2 1 IPEISIQDMTAQVTSPSGK 19 0 Q60FE5;P21333-2;P21333 Q60FE5 FLNA Filamin-A 1 IPEISIQDMTAQVT(0.225)S(0.144)PS(0.63)GK 107.37 0.0002037 4059300.0 15531.0 16967.0 19556.0 22334.0 18581.0 21123.0 20466.0 24848.0 20154.0 19913.0 True False 20469.53493513167 22451.250942231127 19296.674662336583 17185.241356860286 16001.348881406464 19802.175470813272 22287.434352104538 21008.312550236282 21219.29929479354 19215.851931045476 1.0652421245014239 1.1683713541713174 1.0042060446542331 0.8943262790808406 0.8327160793508404 1.0305124925957887 1.1598462785871366 1.0932803096955006 1.1042601374603256 1.0 14.230009318971172 -9.1846007117201 11.801507752969203 1.0000000040381054 1.0365159450596577 0.012507140431521013 0.1020123226470188 7936591.575441903 0.12069017798885603 0.11242733199745464 0.028106832999363632 6.537313138955958e-10 9.1846007117201 0.03651594102155231 IPEPES(ph)PAKPNVPTASTAPPADSR ddPTM_PC-9_AZD4547_30min_R2 4 IPEPESPAKPNVPTASTAPPADSR 24 1 Q9BZL4-3;K7EL81;K7ER83;Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-3;Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 IPEPES(1)PAKPNVPTASTAPPADSR;IPEPES(0.998)PAKPNVPT(0.001)AS(0.001)T(0.001)APPADSR;IPEPES(0.999)PAKPNVPTASTAPPADSR;IPEPES(0.997)PAKPNVPT(0.002)AS(0.001)T(0.001)APPADSR 77.1 0.00010658 38520400.0 71964.0 77106.0 70920.0 71830.0 81511.0 87786.0 95951.0 91476.0 97085.0 89128.0 True False 94847.0550558122 102029.0066099884 69979.5544616952 55270.703262437346 70194.60463227621 82296.72754252754 104490.45311828297 77340.48610936162 102216.71489704428 86007.65584845177 1.1027745625684269 1.1862781935339193 0.8136433178111655 0.642625388602918 0.8161436786041621 0.9568535118261681 1.2148971168612999 0.8992279274026258 1.188460653748701 1.0 16.392177464515356 -7.014340683304461 23.601452737922564 1.0699097156775843 0.9049969616789415 0.1795335644928907 0.1650483747109968 628.3263155919982 1034079.1624577584 0.06762223252286031 0.0545474767194857 9.675185863159906e-08 7.014340683304461 -0.1649127539986428 IPEPES(ph)PAKPNVPTASTAPPADSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IPEPESPAKPNVPTASTAPPADSR 24 1 Q9BZL4-3;K7EL81;K7ER83;Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-3;Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 IPEPES(0.987)PAKPNVPT(0.004)AS(0.004)T(0.004)APPADS(0.001)R;IPEPES(0.997)PAKPNVPT(0.001)AS(0.001)T(0.001)APPADS(0.001)R;IPEPES(0.999)PAKPNVPTASTAPPADSR;IPEPES(0.973)PAKPNVPT(0.01)AS(0.012)T(0.005)APPADSR 73.796 0.00016126 35478100.0 48268.1 47225.1 43722.3 47093.1 66393.0 44590.5 50734.4 40635.1 31884.4 38249.6 True False 56438.93599156951 51913.295828187 44764.80544974611 44454.62628489016 53383.76825613833 42252.09568291102 45928.47034675246 39568.47168144732 32350.64903064146 45183.949696333024 1.2490925731565672 1.1489322243203566 0.9907236031952973 0.9838587946307391 1.181476356425538 0.9351129320671154 1.0164775469037817 0.8757196293678275 0.7159765635377141 1.0 15.463522767107687 -7.275691845742327 1.0878651409340407 0.8486838048235308 1.1038311548777455 0.46335346047365844 0.10795205813575942 0.4781055383632078 1.0974027360358065 0.07777925843897632 0.043658927677403904 5.300394006943966e-08 7.275691845742327 0.25514735005421474 IPEPES(ph)PAKPNVPTASTAPPADSR ddPTM_PC-9_Lapatinib_30min_R1 2 IPEPESPAKPNVPTASTAPPADSR 24 1 Q9BZL4-3;K7EL81;K7ER83;Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-3;Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 IPEPES(0.984)PAKPNVPT(0.002)AS(0.006)T(0.006)APPADS(0.001)R;IPEPES(0.99)PAKPNVPT(0.003)AS(0.003)T(0.004)APPADSR 56.247 0.0033989000000000003 21866500.0 23540.2 34439.0 33187.2 32775.5 45791.0 42250.0 44657.9 41499.0 37081.0 38187.0 True False 23204.512431256037 34359.25861142585 30458.676522296664 35185.91960586284 43097.663408569795 40443.06598956038 46970.0675492171 43427.1950395478 32904.54729975925 44787.572069020905 0.5181015929038573 0.7671605542375848 0.6800698299822466 0.7856179288227273 0.9622683574397193 0.9029975084881734 1.0487299350996926 0.9696260152844037 0.7346803092842575 1.0 15.45081083947104 -5.905423167789105 1.4226573740821669 0.9432085366718856 0.6366086912543004 0.6350716092545099 0.09615260913873162 0.27765531115688535 1.1412001543340458 0.03309931710811521 0.06557030298447913 1.2433025724085765e-06 5.905423167789105 -0.3065998454175852 IPESETESTASAPNS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 IPESETESTASAPNSPR 17 0 G5E9C8;Q07889 G5E9C8 SOS1 Son of sevenless homolog 1 1 IPESET(0.018)ES(0.005)T(0.006)AS(0.125)APNS(0.846)PR;IPESETESTAS(0.019)APNS(0.98)PR 184.97 3.3964e-08 7970000.0 1368.3 3939.6 3413.1 9047.900000000001 5858.9 5473.3 3010.7 3435.4 4081.5 3832.1 True False 1803.3909375919557 5212.9986569230705 3367.8400639200786 6962.046443661514 5045.49286697553 5131.053685764437 3278.646467501276 2904.5378676385117 4297.239757452604 3697.93934540046 0.48767455849026686 1.409703667370061 0.910734262883202 1.882682703360451 1.3644066047895493 1.3875440364230154 0.8866144523379744 0.7854476767584655 1.162063342871635 1.0 11.852505846124691 -7.268672501715981 24.36016130877717 0.9406519876940602 1.2679893072206987 0.1300017810112194 0.35179489573080625 767.3630161129169 2584357.9237248427 0.14503876891211007 0.10016365739471511 5.386758408956046e-08 7.268672501715981 0.32733731952663847 IPESETESTASAPNS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IPESETESTASAPNSPR 17 0 G5E9C8;Q07889 G5E9C8 SOS1 Son of sevenless homolog 1 1 IPESETESTASAPNS(1)PR 116.87 0.00013388 5309800.0 1546.4 1255.8 2453.1 1914.7 2024.4 1502.1 1690.7 1759.6 1392.1 1334.3 True False 1808.1749772077844 1380.4675247069297 2511.591207433557 1807.4255665411545 1627.733352276994 1423.3272317040773 1530.5446563920018 1713.412364450308 1412.456828905545 1576.1980276870106 1.1471750030427255 0.8758211217487023 1.593449023102248 1.1466995484022133 1.032695970737642 0.9030129505952603 0.9710357642294459 1.0870539959783176 0.8961163534624217 1.0 10.622233085709242 -6.282436193129413 3.8155725591221303 0.9780097530914966 1.199632130128095 0.27112306098822003 0.1702825101428287 0.3240538170864707 10.57727228439467 0.054617242859131096 0.06599088895096256 5.21871772398499e-07 6.282436193129413 0.22162237703659837 IPESETESTASAPNS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 IPESETESTASAPNSPR 17 0 G5E9C8;Q07889 G5E9C8 SOS1 Son of sevenless homolog 1 1 IPESETESTAS(0.003)APNS(0.996)PR 116.61 0.0001374 4822400.0 6712.5 5382.1 7409.3 4323.5 6266.1 2503.5 4440.1 4832.5 5819.1 4465.6 True False 6616.778519078262 5369.6380781252365 6800.135954725096 4641.464612773202 5897.5403176265945 2396.4311409435377 4669.986652423846 5057.035591908597 5163.69168016043 5237.473009962027 1.2633532443017277 1.0252345105954384 1.298362004308333 0.8862030608930724 1.1260278203647207 0.45755484302933186 0.8916488244504966 0.965548764125328 0.98591279999701 1.0 12.354655188916698 -5.975762668915218 2.027520994972545 0.8752431564746749 1.1770817641270392 0.32058260147126616 0.18324222624614966 0.3882839998615724 3.2169420971333267 0.05853524299739484 0.09469215708981087 1.057395191411016e-06 5.975762668915218 0.30183860765236437 IPGGNIYIS(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 2 IPGGNIYISPLK 12 0 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 IPGGNIYIS(1)PLK;IPGGNIYIS(1)PLK 115.24 0.00073184 30019000.0 51290.0 65932.0 58234.0 38477.0 49972.0 58233.0 70245.0 65356.0 53335.0 46472.0 True False 67599.15310172577 87243.22962946798 57461.77911058034 29606.722113724052 43034.25037950829 54591.681304353944 76496.66891740348 55256.73193147302 56154.17921443944 44845.02942497593 1.5073945533878317 1.945438117627343 1.2813410950417987 0.6602007511948453 0.9596214102502261 1.217340739973954 1.7058003952339817 1.2321707141237466 1.2521829048720616 1.0 15.452660466782342 -5.400192466149136 5.872538467781425 1.1607406775028646 1.7189825731868207 0.41586704011551134 0.2699841280392974 0.23348235110454796 10.148280101358793 0.07790711046682927 0.16484571761926864 3.979307806119905e-06 5.400192466149136 0.5582418956839561 IPGGNIYIS(ph)PLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IPGGNIYISPLK 12 0 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 IPGGNIY(0.007)IS(0.993)PLK;IPGGNIY(0.003)IS(0.997)PLK 71.933 0.026226 27321000.0 61350.0 103692.0 64525.0 70974.0 79997.0 43713.0 72183.0 54560.0 42008.0 51757.0 True False 71735.34328226706 113985.8564834455 66063.5207124252 66997.55688081266 64322.16211326949 41420.6133276615 65345.30368033591 53127.85781109847 42622.2875286719 61140.13439181345 1.173293843656848 1.8643376828872 1.0805262593807936 1.095803232152913 1.0520448270699598 0.6774701060063035 1.0687791960281579 0.868952257622322 0.6971245312535483 1.0 15.899832102958332 -5.63769853091577 1.7836682046610333 0.8955847520945556 1.514791009084902 0.5295244601475744 0.2146914129995032 0.2573735130130005 1.636668993112159 0.06252701088607009 0.15057957859749224 2.3030399367720826e-06 5.63769853091577 0.6192062569903464 IPGGNIYIS(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 2 IPGGNIYISPLK 12 0 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 IPGGNIYIS(1)PLK;IPGGNIYIS(1)PLK 154.72 0.00028172 27265000.0 43097.0 113294.0 80641.0 93812.0 115084.0 96332.0 113879.0 120077.0 88307.0 76802.0 True False 42482.428876978156 113031.67470376288 74011.00826326187 100711.24742765825 108314.98538384934 92212.10492085989 119775.09740577366 125656.21578264034 78360.9357460651 90077.12336776752 0.4716228415013942 1.2548321979852348 0.821640450939904 1.118055768904538 1.2024694099257605 1.0237017066406044 1.3296949650218628 1.394984776207942 0.8699315965734442 1.0 16.45887313492804 -4.754305695806947 24.98459754720213 1.1230149988384617 0.47162169994792136 0.535398241019013 0.17896125586388706 194.72723113821087 681942.1328245075 0.04432844280753329 0.4379633869848811 1.7607362444146025e-05 4.754305695806947 -0.6513932988905403 IPGGNIYIS(ph)PLKSPYK ddPTM_PC-9_AZD4547_30min_R2 2 IPGGNIYISPLKSPYK 16 1 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 IPGGNIY(0.091)IS(0.901)PLKS(0.008)PYK;IPGGNIY(0.001)IS(0.999)PLKS(0.001)PYK 56.9 0.028170999999999998 85291000.0 158993.0 115653.0 205385.0 255830.0 209988.0 191640.0 182178.0 226993.0 145056.0 170639.0 True False 209549.4667401577 153035.57053231884 202661.46070382485 196852.34603409882 180834.79085672312 179656.72050497791 198391.4890744502 191916.44763022344 152723.36402230684 164664.98054846935 1.2725806424789667 0.9293753293662378 1.2307502179807515 1.1954718324346754 1.09819823410172 1.09104388745302 1.2048189506575346 1.1654964339775487 0.9274793190003902 1.0 17.329174242852638 -8.25862266808043 24.935775076279675 0.9637396478686912 1.1437621711164072 0.3917940809824424 0.09191406577839209 228.2142143826347 2020384.7578384334 0.0658447961575378 0.022345146671558718 5.512864674899749e-09 8.25862266808043 0.18002252324771606 IPGGNIYIS(ph)PLKSPYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IPGGNIYISPLKSPYK 16 1 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 IPGGNIY(0.01)IS(0.989)PLKS(0.002)PYK;IPGGNIY(0.006)IS(0.747)PLKS(0.239)PY(0.008)K;IPGGNIY(0.002)IS(0.994)PLKS(0.004)PYK 102.03 0.0054667000000000006 74213000.0 160265.0 172326.0 174058.0 207073.0 205030.0 197763.0 199799.0 162989.0 192452.0 149743.0 True False 187394.69912196428 189433.386417142 178208.2028386408 195471.37114972353 164855.8433201697 187391.9601381357 180872.59230050605 158710.7114511205 195266.24641658596 176890.22053506406 1.0593841680739946 1.0709093235574976 1.0074508488914202 1.1050434023907851 0.9319669726314301 1.0593686839855 1.0225132387386706 0.8972271670590183 1.103883786372912 1.0 17.43249476454792 -6.247270417604127 24.996982737953093 1.0011994278091547 1.0576230950421348 0.18790091928074404 0.05910362974559073 1433.4049617853914 2528823.146982152 0.016645069548785574 0.021400744190225647 5.658868244847604e-07 6.247270417604127 0.05642366723298009 IPGGNIYIS(ph)PLKSPYK ddPTM_PC-9_Lapatinib_30min_R1 2 IPGGNIYISPLKSPYK 16 1 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 IPGGNIY(0.035)IS(0.929)PLKS(0.036)PYK;IPGGNIY(0.014)IS(0.971)PLKS(0.015)PYK 65.92399999999999 0.013028999999999999 68581000.0 145794.0 136868.0 159250.0 123579.0 140786.0 130275.0 130483.0 121606.0 151064.0 97972.0 True False 143714.95082465484 136551.09055514453 146157.07972277718 132667.41190745903 132505.24427592565 124703.44193585753 137238.77128177747 127256.25870452888 134049.5815455578 114906.32966051558 1.2507139619658267 1.1883687431195236 1.2719671766959246 1.1545700946102586 1.1531587917515518 1.085261728438172 1.1943534502167275 1.1074782310121687 1.1665987586723892 1.0 16.810098746035443 -8.595047933928406 0.02432940000464507 2.630653804691025e-10 2.214576207345194 0.6586948232315405 0.0440060412742579 162.97225384112065 2.438948029395884 114.57893783532255 106.51401962424119 2.540692268915902e-09 8.595047933928406 2.2145762070821284 IPGTPGAGGRLS(ph)PENNQVLTK ddPTM_PC-9_AZD4547_30min_R2 2 IPGTPGAGGRLSPENNQVLTK 21 1 Q16514-2;Q16514 Q16514-2 TAF12 Transcription initiation factor TFIID subunit 12 1 IPGT(0.017)PGAGGRLS(0.983)PENNQVLTK;IPGT(0.04)PGAGGRLS(0.951)PENNQVLT(0.01)K 91.73299999999999 0.00019421 157039000.0 101627.0 87042.0 141505.0 165836.0 134297.0 131219.0 117206.0 145244.0 109072.0 119485.0 True False 133942.2720270831 115176.62430091827 139628.55124227534 127605.07234065914 115652.17968496014 123013.85518650977 127637.10694189223 122799.87717508501 114837.3232450988 115301.86651840355 1.1616661210398038 0.9989137884644279 1.2109825752039232 1.1067043075169287 1.0030382263282847 1.066885202303948 1.1069821399770647 1.065029395300246 0.9959710689225434 1.0 16.815056342110353 -7.629862353783066 0.3228574790600406 0.9892527469804122 1.124908058459809 0.2718124952849734 0.06089237029713024 2.2393017748022874 0.7266839404756605 0.09446728875343442 0.1070232365332689 2.34497191794138e-08 7.629862353783066 0.1356553114793968 IPGTPGAGGRLS(ph)PENNQVLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IPGTPGAGGRLSPENNQVLTK 21 1 Q16514-2;Q16514 Q16514-2 TAF12 Transcription initiation factor TFIID subunit 12 1 IPGT(0.005)PGAGGRLS(0.995)PENNQVLTK;IPGT(0.002)PGAGGRLS(0.997)PENNQVLT(0.001)K;IPGT(0.002)PGAGGRLS(0.998)PENNQVLTK;IPGT(0.022)PGAGGRLS(0.964)PENNQVLT(0.013)K 66.60600000000001 0.0018594000000000002 136473700.0 141458.0 107934.0 138177.0 160938.0 166244.0 157619.0 150999.0 158876.0 157849.0 124054.0 True False 165404.04547714628 118648.97420904407 141471.6637191903 151921.16562803596 133669.68159253945 149353.1821676085 136695.28158191007 154705.67334303688 160157.2430040309 146544.0081890766 1.1286987951341945 0.809647393129569 0.9653868859425372 1.0366931238295432 0.9121470283525601 1.0191694905390292 0.9327933858990719 1.0556942945318502 1.0928951990816984 1.0 17.16097445554768 -7.776505406479298 24.060991520244936 1.05572115530325 0.9675635521342411 0.1553104256735871 0.08192411491079592 255.45999138127553 407969.86291718425 0.04206859407368635 0.020350459912334397 1.6729948093596646e-08 7.776505406479298 -0.08815760316900889 IPGTPGAGGRLS(ph)PENNQVLTK ddPTM_PC-9_Lapatinib_30min_R1 2 IPGTPGAGGRLSPENNQVLTK 21 1 Q16514-2;Q16514 Q16514-2 TAF12 Transcription initiation factor TFIID subunit 12 1 IPGT(0.012)PGAGGRLS(0.98)PENNQVLT(0.008)K;IPGTPGAGGRLS(0.978)PENNQVLT(0.022)K 57.735 0.0065673 125437000.0 328210.0 266140.0 298580.0 256710.0 295120.0 286320.0 237100.0 222910.0 305900.0 235250.0 True False 323529.6652136574 265523.76918159233 274031.9049521303 275589.3097594557 277761.6218282438 274074.76104451896 249375.87786079 233267.212372963 271446.32073019457 275912.64904907875 1.1725800405624343 0.9623472142241711 0.9931835524633236 0.9988281099444427 1.006701297622771 0.9933388773189848 0.9038218389778555 0.8454386313092515 0.9838125278624332 1.0 18.073852072128616 -7.110895661194855 3.6680108113574494 0.9207692046936801 1.018625702356947 0.293274915021873 0.06661034307376432 0.2988325104762425 7.26468150722123 0.026189431840306795 0.02005759020858318 7.746478838100278e-08 7.110895661194855 0.09785649766326687 IPMPPS(ph)SPQPR ddPTM_PC-9_AZD4547_30min_R2 2 IPMPPSSPQPR 11 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 IPMPPS(0.5)S(0.5)PQPR;IPMPPS(0.5)S(0.5)PQPR 86.11399999999999 0.009769700000000001 18159900.0 61181.0 63299.0 76841.0 108164.0 99482.0 89387.0 72057.0 91369.0 84441.0 88196.0 True False 80635.28535614528 83759.16387058927 75822.03813298252 83228.46091714139 85670.64148431596 83797.61675943676 78469.93340709466 77250.02050074613 88904.37887028193 85108.28488477321 0.9474434300411075 0.9841481823301869 0.8908890390123217 0.9779125619770521 1.0066075423832606 0.9845999936773377 0.9220011132092945 0.9076674568795945 1.044603107566416 1.0 16.377011957763806 IPMPPS(ph)SPQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IPMPPSSPQPR 11 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 IPMPPS(0.5)S(0.5)PQPR 67.87899999999999 0.033993999999999996 6642500.0 21632.0 27895.0 33810.0 28366.0 41459.0 36138.0 35525.0 34174.0 34366.0 33181.0 True False 25293.87034852481 30664.231248367407 34616.15862513902 26776.74498381281 33335.40656592173 34242.85966268686 32159.814821272772 33276.96871034604 34868.53773591552 39196.452639348514 0.6453101912373778 0.782321592479627 0.8831451902968527 0.6831420493632168 0.8504699869818576 0.8736213957359793 0.8204776875392085 0.8489790904429951 0.8895840155930771 1.0 15.258435472890007 -1.9855264580358205 0.0632052894625627 1.2338920756107155 1.6465435477542616e-15 0.6138291007173506 0.06086984158781598 205.9345156746363 1.058093441087241 4.26885188542067 23.521647568899713 0.010338881126573427 1.9855264580358205 -1.233892075610714 IPMPPS(ph)SPQPR ddPTM_PC-9_Lapatinib_30min_R1 4 IPMPPSSPQPR 11 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 IPMPPS(0.5)S(0.5)PQPR;IPMPPS(0.81)S(0.19)PQPR;IPMPPS(0.77)S(0.23)PQPR;IPMPPS(0.5)S(0.5)PQPR 98.182 0.0044751999999999995 30156200.0 119536.0 109789.0 116133.0 98942.0 133025.0 148070.0 148285.0 135134.0 150210.0 125108.0 True False 117831.39471978211 109534.79031591625 106584.99302634403 106218.52474083612 125200.73103721239 141737.39126802856 155962.47173592265 141412.81897092127 133291.76801857658 146732.75110406856 0.8030340454545932 0.7464917647337637 0.7263885684985885 0.7238910464201807 0.8532568911518272 0.9659560677595617 1.0629015714788037 0.9637440714965251 0.908398207050864 1.0 17.16283139440442 -6.584700550295632 2.714403976056885 0.9845912965628111 0.7488546123889505 0.8727448740789367 0.041491021888354664 0.0948828170585472 1.4195784985530986 0.015652130823739216 0.016089465616590845 2.6019530133198473e-07 6.584700550295632 -0.23573668417386062 IPMPPSS(ph)PQPR ddPTM_PC-9_AZD4547_30min_R2 1 IPMPPSSPQPR 11 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 IPMPPS(0.226)S(0.774)PQPR 67.87899999999999 0.033993999999999996 10949000.0 22343.0 36737.0 47710.0 51636.0 49545.0 60517.0 46859.0 54809.0 46358.0 47692.0 True False 29447.60923672958 48611.516818809774 47077.3342268398 39732.117968247425 42666.53195895176 56732.86242329246 51029.36022208865 46339.52843552401 48808.38923826726 46022.317596315 0.6398549828591736 1.0562596444013521 1.022924022205463 0.8633228408173163 0.9270835148547162 1.2327250209545086 1.1087959687231086 1.006892543786939 1.060537404187036 1.0 15.49004601631703 -6.614855368053525 11.609556899726675 1.0838347484553699 0.9135526946403789 0.3550283199094888 0.12084910961321596 0.5758169833124233 68.92213588931442 0.03990283777056353 0.039896060037667117 2.4274183572248877e-07 6.614855368053525 -0.17028205381499095 IPMPPSS(ph)PQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IPMPPSSPQPR 11 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 IPMPPS(0.168)S(0.832)PQPR 91.12299999999999 0.007365100000000001 9088800.0 19334.0 16228.0 21410.0 23535.0 32439.0 44096.0 34133.0 34278.0 30102.0 30062.0 True False 22606.864336093713 17839.00859288427 21920.49559787715 22216.410251499485 26082.81081530995 41783.528133428525 30899.67513848002 33378.23882054313 30542.18480261095 35512.00262933895 0.636597844735926 0.5023374428944826 0.617270048852922 0.6256028555580516 0.734478736317763 1.176602980393683 0.8701191949380978 0.9399142923290681 0.8600524482214899 1.0 15.116019100143468 -6.5523184908523975 6.259030943399898 0.9605544737011147 0.6002313640258833 0.7988640232784918 0.08892985083982939 0.07802971122639552 9.559625517716835 0.02975054528661995 0.030190469609504663 2.80337702097628e-07 6.5523184908523975 -0.3603231096752314 IPMTPTSSFVSPPPPT(ph)ASPHSNR ddPTM_PC-9_AZD4547_30min_R2 2 IPMTPTSSFVSPPPPTASPHSNR 23 0 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 IPMTPTSSFVSPPPPT(0.575)AS(0.386)PHS(0.039)NR;IPMTPTSSFVSPPPPT(0.578)AS(0.402)PHS(0.02)NR 107.31 3.9218e-06 31504000.0 22263.9 22742.3 35658.2 38267.1 36952.0 36519.9 32375.4 47270.0 35062.2 33596.6 True False 29343.357082111776 30093.303725084166 35185.348969346014 29445.211315801404 31821.85263794906 34236.30487982549 35256.747880539675 39965.507656538495 36915.516311100015 32420.393260009183 0.9050894863236296 0.9282214279061353 1.0852844592957922 0.9082311580755039 0.9815381443013393 1.0560114001472107 1.0874867432292734 1.2327274174627694 1.1386510957791374 1.0 14.98461397043032 -7.021007998709329 1.8852567072656827 1.137640919731248 0.9618730939403024 0.49731136239097296 0.07227852012178997 0.2709279903992735 1.9304451483694995 0.032977177178126704 0.024966694082648254 9.527786158628959e-08 7.021007998709329 -0.17576782579094563 IPMTPTSSFVSPPPPT(ph)ASPHSNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IPMTPTSSFVSPPPPTASPHSNR 23 0 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 IPMTPTSSFVS(0.001)PPPPT(0.557)AS(0.395)PHS(0.046)NR;IPMTPTSSFVSPPPPT(0.59)AS(0.397)PHS(0.013)NR 104.01 2.8158999999999996e-06 57236000.0 18136.7 22362.3 26592.0 21468.2 25109.0 22288.6 25643.0 16439.4 17277.9 13781.5 True False 21206.88509384663 24582.2813567079 27226.0541307216 20265.406354843486 20189.071696464656 21119.746579162176 23213.909400757148 16007.883168984086 17530.556600924592 16279.976855706032 1.3026360714028746 1.5099702889376012 1.672364424841245 1.2448055998151242 1.240116732069463 1.2972835751765723 1.4259178379986956 0.9832866048193073 1.0768170468731495 1.0 13.990811028159637 -7.460416556742928 0.5556223571844994 0.9697308605453927 1.4691966209321523 0.5557180487412641 0.13969985824711487 0.6569294140002883 0.42565136889382377 0.14067327196788762 0.10011924889075957 3.464044347000556e-08 7.460416556742928 0.4994657603867596 IPMTPTSSFVSPPPPT(ph)ASPHSNR ddPTM_PC-9_Lapatinib_30min_R1 1 IPMTPTSSFVSPPPPTASPHSNR 23 0 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 IPMTPTSSFVSPPPPT(0.633)AS(0.335)PHS(0.032)NR 116.05 6.291800000000001e-08 12828000.0 11325.0 15379.0 18279.0 12497.0 19803.0 16469.0 13842.0 13949.0 18656.0 18351.0 True False 11163.503423249356 15343.390870382935 16776.171178980472 13416.071068769907 18638.226474195988 15764.65926111409 14558.671030573836 14597.121463328092 16554.764823610705 21522.94589882952 0.5186791564558297 0.7128852594113222 0.7794551572000564 0.6233380473023218 0.8659700471211791 0.7324582487554093 0.6764255738507237 0.6782120594431232 0.7691681659856331 1.0 14.393587936196901 -14.522878745280336 0.2192480392912999 2.4516267289166946 0.6738594138942635 0.5295559848635103 0.0859230552899325 128.60061401619373 1.2830712149976187 82.50998354631547 0.16783001156363156 3.0000000000000132e-15 14.522878745280336 -1.7777673150224311 IPMTPTSSFVSPPPPTAS(ph)PHSNR ddPTM_PC-9_AZD4547_30min_R2 2 IPMTPTSSFVSPPPPTASPHSNR 23 0 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 IPMTPTSSFVSPPPPT(0.21)AS(0.763)PHS(0.027)NR;IPMTPTSSFVSPPPPT(0.334)AS(0.611)PHS(0.056)NR 98.15100000000001 5.1342e-06 57718000.0 18309.8 16928.2 23411.0 26877.0 26275.0 28054.5 24329.5 24948.4 25715.0 27360.0 True False 24131.93553250105 22399.909601006493 23100.554843524325 20680.922895510623 22627.16978951373 26300.2476800611 26494.77836751329 21093.198037198756 27074.242401787018 26402.13472773588 0.9140145591011644 0.848412820857058 0.8749502675348751 0.783304952753876 0.8570204653089476 0.9961409541794457 1.0035089450429964 0.7989201727328511 1.0254565655763084 1.0 14.688366962035026 -6.742455542770073 22.285295289369905 0.954656766887905 0.8522096803799885 0.3965453505624341 0.06674757048497507 77.07006586198192 90472.06878340154 0.021936107773395438 0.021881557814809768 1.8094411270281362e-07 6.742455542770073 -0.10244708650791656 IPMTPTSSFVSPPPPTAS(ph)PHSNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IPMTPTSSFVSPPPPTASPHSNR 23 0 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 IPMTPTSS(0.001)FVS(0.006)PPPPT(0.265)AS(0.686)PHS(0.042)NR;IPMTPTSSFVSPPPPT(0.244)AS(0.666)PHS(0.09)NR 82.94200000000001 5.4359e-05 13187400.0 11031.9 20313.6 20730.7 21680.0 22313.6 14865.9 17734.699999999997 16181.1 13779.9 14641.199999999999 True False 12899.382780043034 22330.1999600945 21224.99850961756 20465.33988750835 17941.410259517867 14086.306034078709 16054.74082789095 15756.363270292617 13981.404968490433 17295.533660324574 0.745821611138477 1.291096325713227 1.2271953514974248 1.1832731090833708 1.0373435484488642 0.8144476088871582 0.9282593496793935 0.9110076381417032 0.8083823976223035 1.0 14.078111908855881 -6.564215114896263 4.8173930423133635 0.8901447284802768 1.1312104682073563 0.3349820401545427 0.1458502822819298 0.2111797089477878 11.309768364384468 0.04795529798435802 0.048821322138957825 2.7276263992797076e-07 6.564215114896263 0.24106573972707945 IPMTPTSSFVSPPPPTAS(ph)PHSNR ddPTM_PC-9_Lapatinib_30min_R1 3 IPMTPTSSFVSPPPPTASPHSNR 23 0 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 IPMTPTSSFVSPPPPT(0.222)AS(0.758)PHS(0.02)NR;IPMTPTSSFVSPPPPT(0.049)AS(0.902)PHS(0.049)NR;IPMTPTSSFVSPPPPT(0.255)AS(0.683)PHS(0.062)NR 125.53 1.3153e-07 41655000.0 27141.0 33295.9 42140.8 36258.1 48971.5 43016.3 35518.3 45856.5 40020.4 37575.9 True False 26753.964362950162 33218.80538924399 38676.14609219217 38924.641627475874 46091.0926516734 41176.59312489295 37357.26378162337 47987.160397383625 35512.881118505036 44070.84424826051 0.6070672077947803 0.7537592246274054 0.8775903151371721 0.8832288623336786 1.0458409281209229 0.9343273047581384 0.8476639015849549 1.0888641054176695 0.8058134969789407 1.0 15.427536913585092 -4.888843232573887 1.1063252938271846 0.950629627774472 0.47777747028611206 0.6464403204065448 0.08093638811561482 0.8508099376896272 0.9785498033177653 0.02455382674211469 0.45200697534061146 1.2916854496045151e-05 4.888843232573887 -0.47285215748835996 IPNSYEVLFPES(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 1 IPNSYEVLFPESPAR 15 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 IPNSYEVLFPES(1)PAR 100.69 0.0094762 0.0 925.71 831.24 823.64 2586.4 2422.0 907.74 1131.7 2659.9 1079.4 1116.2 True False 1220.066524035847 1099.9220742158427 812.717995443184 1990.1454394816635 2085.7471067631695 850.9788743017576 1232.4191076066015 2248.87357342134 1136.454880361226 1077.1221777448382 1.1327095005974996 1.0211674190190203 0.7545272135652846 1.8476506013908418 1.9364071688971078 0.7900486053341182 1.1441776365490006 2.0878537457373576 1.0550844684496352 1.0 10.072966188424749 -5.746491754962084 24.98077797365281 1.4392564717667051 0.9746380061581743 0.18472778051950656 0.4194401989642702 398.6735998320159 666266.0745813657 0.11616364073853756 0.20016709985613207 1.7927025863242968e-06 5.746491754962084 -0.4646184656085308 IPNY(ph)QLSPTKLPSINK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IPNYQLSPTKLPSINK 16 1 A0A0C4DG07;O60934 A0A0C4DG07 NBN Nibrin 1 IPNY(0.997)QLS(0.003)PTKLPSINK;IPNY(0.987)QLS(0.012)PTKLPSINK 104.95 0.0055317 295280000.0 161876.0 138566.0 155712.0 197744.0 178458.0 171676.0 181552.0 180332.0 156116.0 142825.0 True False 189278.40960326363 152321.916729209 159424.7646210481 186665.04477469783 143490.43597147168 162673.00834167426 164354.08023734615 175598.47607754753 158398.90115754493 168718.04189792194 1.1218622944769663 0.9028193725800058 0.9449182958008931 1.1063727546555704 0.8504747587000002 0.9641707935426073 0.9741345880293224 1.0407806663841463 0.9388379534026342 1.0 17.36425473119747 -11.04436422665828 14.416325682897078 1.0000000021878892 0.9799054610935388 0.0030094113884098217 0.08107873083043969 6.304923461319236e-09 1.9320837402957866e-10 0.07476879024088941 0.01813409297742255 9.028919341622924e-12 11.04436422665828 -0.020094541094350382 IPNYQLS(ph)PTKLPSINK ddPTM_PC-9_AZD4547_30min_R2 1 IPNYQLSPTKLPSINK 16 1 A0A0C4DG07;O60934 A0A0C4DG07 NBN Nibrin 1 IPNYQLS(0.911)PT(0.084)KLPS(0.005)INK 89.23200000000001 0.018366 11388000.0 24512.0 21590.0 22871.0 30535.0 24633.0 29745.0 26826.0 27577.0 23236.0 30865.0 True False 32306.306118726912 28568.545284538828 22567.71559635407 23495.627511047238 21213.133146530614 27885.040447821833 29213.462031151954 23315.608306417664 24464.20752276583 29784.42574457484 1.0846711095180819 0.9591773072792085 0.7577018872175074 0.7888561529619857 0.7122223315114455 0.9362289099329378 0.9808301251694642 0.782812081265812 0.8213758335502549 1.0 14.862270523172118 -4.977667044319422 3.7637504697491777 0.840891631525827 1.0747993760566867 0.39597410680868417 0.09199997534921285 0.22372774630665654 6.770562876711676 0.02439692393795155 0.11064926050523052 1.0527686788696617e-05 4.977667044319422 0.23390774453085972 IPNYQLS(ph)PTKLPSINK ddPTM_PC-9_Lapatinib_30min_R1 1 IPNYQLSPTKLPSINK 16 1 A0A0C4DG07;O60934 A0A0C4DG07 NBN Nibrin 1 IPNY(0.008)QLS(0.866)PT(0.126)KLPSINK 108.14 0.004000699999999999 10257000.0 39109.0 36179.0 42708.0 35380.0 35504.0 34564.0 32245.0 30034.0 34023.0 32519.0 True False 38551.298488287786 36095.229748331134 39196.71309764747 37981.963224220155 33415.72452354967 33085.77829261929 33914.48832400326 31429.48928450755 30190.971461926823 38139.8658211562 1.0107874702302535 0.9463911047193326 1.0277097796160846 0.9958599068576571 0.8761363944026764 0.8674854402415488 0.8892136244797924 0.8240587272090926 0.7915856758253166 1.0 15.219012147702136 -6.280912696346321 5.308537568222692 0.8655590511273663 0.9945042335358554 0.5376168917538521 0.0543709968737577 0.1335546691664243 12.076640487241438 0.01637912813321628 0.019418362071742908 5.237057034680724e-07 6.280912696346321 0.12894518240848907 IPNYQLSPT(ph)K ddPTM_PC-9_AZD4547_30min_R2 2 IPNYQLSPTK 10 0 A0A0C4DG07;O60934 A0A0C4DG07 NBN Nibrin 1 IPNYQLS(0.13)PT(0.87)K;IPNYQLS(0.292)PT(0.708)K 120.55 0.0017032 42964000.0 99152.0 106336.0 99960.0 86138.0 82557.0 89628.0 104889.0 105854.0 108243.0 89898.0 True False 130680.27351028121 140707.03248618438 98634.46508729627 66280.21491883363 71095.38558755029 84023.54699133908 114223.91780308283 89496.69658293255 113964.50399753591 86750.69838282155 1.5063887201645705 1.6219700257081426 1.1369875623598202 0.7640309087351221 0.8195367520133839 0.968563349433248 1.316691622458472 1.0316539030958944 1.3137012856613874 1.0 16.404587751642396 -5.341885964321834 4.581791018739516 1.027976037429581 1.5643564736639275 0.6000512089715004 0.1711127887235947 0.14615757578401964 5.523382190404664 0.04928717531608076 0.10960166468275828 4.5510754516917315e-06 5.341885964321834 0.5363804362343465 IPNYQLSPT(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IPNYQLSPTK 10 0 A0A0C4DG07;O60934 A0A0C4DG07 NBN Nibrin 1 IPNYQLS(0.082)PT(0.918)K;IPNYQLS(0.26)PT(0.74)K;IPNYQLS(0.034)PT(0.966)K;IPNYQLS(0.065)PT(0.935)K 137.4 0.00028653 46160200.0 101084.0 156442.0 116080.0 103555.0 100250.0 68032.0 104278.0 79053.0 68324.0 66985.0 True False 118195.52469999438 171972.52787084057 118847.78743585128 97753.14907983974 80606.73215064654 64464.282156508685 94400.03293265837 76977.94251357699 69323.10924369116 79128.85024703179 1.4937096183124186 2.1733227177440435 1.50195266410192 1.2353667312827734 1.018676903544042 0.8146748241034478 1.1929913380259107 0.9728176546640082 0.8760788135714324 1.0 16.27191617437044 -5.746987752473853 2.060121556488928 0.9852512381144038 1.837696156408444 0.7675948575649779 0.18647193570035575 0.13549945412935227 1.172481606682609 0.0537801639839531 0.10643534784231184 1.79065635157133e-06 5.746987752473853 0.8524449182940401 IPS(ph)LGWSPSK ddPTM_PC-9_AZD4547_30min_R2 1 IPSLGWSPSK 10 0 Q8IVF2-3;Q8IVF2 Q8IVF2-3 AHNAK2 Protein AHNAK2 1 IPS(0.593)LGWS(0.406)PS(0.001)K 80.165 0.018029 6975100.0 19717.0 15800.0 27231.0 35401.0 33984.0 23447.0 32194.0 29038.0 25873.0 34987.0 True False 25986.595860922756 20907.04101415995 26869.899147580683 27239.846389997816 29265.90820653984 21980.85538342842 35059.20363195806 24550.844326857747 27240.593959223625 33762.11577921398 0.7696969002434881 0.6192455813753118 0.7958594574846946 0.8068169236825001 0.8668268421897221 0.6510508857670934 1.0384184409894905 0.7271713801174968 0.8068390659330242 1.0 15.04311769616961 -14.522878745179883 0.03224905130996025 2.1293665076902437 0.047749578678507314 0.3094294136664878 0.10571382198457685 1566.4080425335578 3.7828824716905673 196.9783576117993 74.40366284410447 3.000000000693918e-15 14.522878745179883 -2.0816169290117363 IPS(ph)PNILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IPSPNILK 8 0 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 IPS(1)PNILK 90.149 0.009692000000000001 52043000.0 122620.0 142090.0 160750.0 177390.0 195130.0 172630.0 177060.0 175330.0 165580.0 126840.0 True False 143377.1441446059 156195.75615990386 164582.88964777006 167451.41340613924 156895.67725242508 163576.97890225338 160287.59499660926 170727.77327749046 168001.29425341586 149835.08793511268 0.9568996562854261 1.042451126184447 1.0984268899621432 1.1175714294548649 1.0471224024667043 1.0917134374632713 1.0697600755974004 1.1394378688617017 1.1212413365163854 1.0 17.19301598383 -4.841248999051533 2.437328750476944 1.0898825122433293 0.9362732842829933 0.5096115558965288 0.03831760498299023 0.357110949023317 2.958770368303041 0.009764282517695344 0.11097581943453916 1.441288763921085e-05 4.841248999051533 -0.15360922796033605 IPS(ph)PNILK ddPTM_PC-9_Lapatinib_30min_R1 1 IPSPNILK 8 0 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 IPS(1)PNILK 85.807 0.012949 61168000.0 124310.0 103030.0 119530.0 111920.0 102820.0 109910.0 97811.0 95510.0 111810.0 77794.0 True False 122537.31660433767 102791.44036514455 109702.70479914306 120150.97015417521 96772.32975189772 105209.40551272394 102875.17498710148 99947.74327639716 99216.78038850296 91240.58924601071 1.343013209548023 1.1265977260185096 1.202345422204072 1.3168587702805585 1.0606280664296441 1.1530987072984513 1.1275154603585538 1.095430708003315 1.0874193295813352 1.0 16.47738814338004 -1.5228789425206273 0.10294753358062696 0.9113142318224292 1.9756696178987811 0.5646449744055906 0.06801647722649738 95.47633910756802 0.6962157067397995 0.7882707283412493 14.368370328935544 0.029999986375126568 1.5228789425206273 1.064355386076352 IPSAS(ph)PQTQR ddPTM_PC-9_AZD4547_30min_R2 1 IPSASPQTQR 10 0 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 IPS(0.173)AS(0.799)PQT(0.028)QR 80.87100000000001 0.017062 12506000.0 4621.6 5577.5 8518.2 22698.0 22390.0 7841.1 8367.0 18582.0 9104.5 9061.6 True False 6091.17266474822 7380.317801042855 8405.243102306997 17465.326780604224 19281.53497953235 7350.794777455563 9111.646790973253 15710.578871880647 9585.745282794858 8744.356142136381 0.6965833236590994 0.8440092879428089 0.9612192099318436 1.997325646018024 2.2050262667848717 0.8406330503894196 1.0420031667130998 1.796653591929561 1.0962208225490817 1.0 13.094136445282002 -5.543508532185429 23.9209475833925 1.452940604507877 0.8033756079088403 0.28672740431036126 0.4323628724984765 175.97774402150117 204050.9944158305 0.12365639195231223 0.21421571638518283 2.860826156047056e-06 5.543508532185429 -0.6495649965990367 IPSAS(ph)PQTQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IPSASPQTQR 10 0 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 IPS(0.017)AS(0.983)PQTQR 114.76 0.0011805 7889800.0 6860.4 0.0 3060.6 6810.6 18247.0 7499.9 6068.8 8028.2 5379.2 6967.1 True False 8021.730220923615 0.0 3133.5763113901367 6429.024162263112 14671.631337185498 7106.592041180615 5493.919329692895 7817.468256581024 5457.860623553417 8230.180078466748 0.9746725034500135 0.0 0.38074213219085606 0.7811523078436474 1.782662250072998 0.8634795318481714 0.6675333075720977 0.9498538527771059 0.6631520296661839 1.0 13.006708282194614 -5.888561576898698 4.811346887543874 0.9879203206906932 0.41140181767451295 0.2940015828781313 0.3676580934955658 0.2536129042982188 9.612215230509602 0.10752436553496426 0.16333096121756505 1.2925234260243325e-06 5.888561576898698 -0.5765185030161804 IPSAS(ph)PQTQR ddPTM_PC-9_Lapatinib_30min_R1 2 IPSASPQTQR 10 0 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 IPS(0.018)AS(0.981)PQT(0.001)QR;IPS(0.001)AS(0.997)PQT(0.002)QR 110.98 0.0016618 31102000.0 26907.2 51476.0 62182.0 54528.0 57736.0 44763.3 30002.1 35489.6 57386.0 39650.5 True False 26523.498393823847 51356.81048467603 57069.63598946135 58538.171020075606 54340.0819933434 42848.87800734887 31555.461936597272 37138.57637715451 50922.58437863013 46504.03609402976 0.5703483099874198 1.104351682095595 1.2271974818286366 1.25877613938096 1.1685024904821033 0.9214012719392727 0.678553187787681 0.798609744368455 1.0950142967304213 1.0 15.505068312977661 -6.902554185236865 5.990265634811406 0.8661220477693417 1.0865404713803695 0.1306544309652954 0.20815771560862942 0.36697087576664833 18.888175558779096 0.07709194175743564 0.06790567075570249 1.2515431131136275e-07 6.902554185236865 0.22041842361102781 IPSIVS(ph)SPLNSPLDR ddPTM_PC-9_AZD4547_30min_R2 2 IPSIVSSPLNSPLDR 15 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 IPSIVS(0.61)S(0.39)PLNSPLDR;IPS(0.063)IVS(0.867)S(0.07)PLNSPLDR 158.65 0.00012298 24233000.0 35797.0 39727.0 41460.0 50484.0 46474.0 42473.0 34108.0 48475.0 40232.0 38476.0 True False 47179.701376145014 52567.97584617291 40910.213310517225 38845.69377002485 40021.88729963316 39817.156595741704 37143.54592404874 40984.30259468384 42358.58138474413 37128.96695118293 1.2706979280672357 1.415821127350221 1.1018408716920638 1.0462368592452107 1.0779154548591088 1.0724014123014303 1.0003926576488105 1.103836329423598 1.140849984876689 1.0 15.18025755482455 -5.338741870667162 5.624169279781644 1.067043653074471 1.3421664828958997 0.81588386948314 0.052436437641043776 0.07562481279231724 4.129900161486373 0.013343053549169474 0.02865023716415092 4.584142710440659e-06 5.338741870667162 0.27512282982142877 IPSIVS(ph)SPLNSPLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IPSIVSSPLNSPLDR 15 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 IPSIVS(0.812)S(0.188)PLNSPLDR;IPSIVS(0.912)S(0.081)PLNS(0.006)PLDR;IPS(0.004)IVS(0.498)S(0.498)PLNSPLDR 179.55 2.887e-05 15719700.0 46233.7 48150.1 43666.3 49466.0 54968.3 40523.6 48327.1 46448.9 45751.0 35178.6 True False 54060.152252801076 52930.123715074966 44707.470197364935 46694.58039093577 44197.656208243185 38398.47107827932 43749.20723009517 45229.66559167763 46420.021822611605 41556.201706355634 1.3008925270601206 1.2736997497771745 1.0758314851120607 1.1236489013334023 1.0635634247940318 0.9240130113336761 1.052772039640094 1.0883974890505976 1.117041979693541 1.0 15.342776175518557 -5.216953994412189 1.4239451334977988 1.0462420421723542 1.340104437508144 0.7343823147728528 0.05564873298947448 0.33090570089796373 1.0194114076667136 0.01788861304769849 0.11012166353065818 6.068006056526854e-06 5.216953994412189 0.29386239533578973 IPSIVS(ph)SPLNSPLDR ddPTM_PC-9_Lapatinib_30min_R1 1 IPSIVSSPLNSPLDR 15 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 IPSIVS(0.561)S(0.438)PLNS(0.001)PLDR 158.65 0.00025144 8479600.0 14766.0 13597.0 14695.0 14595.0 14827.0 17385.0 17619.0 19939.0 20618.0 16934.0 True False 14555.434132247243 13565.516981897183 13486.83382434039 15668.364987492738 13954.905011003566 16641.484076414377 18531.2256095709 20865.43873089819 18295.78372283476 19861.01933686334 0.7328644056668034 0.6830221929605951 0.6790605051830322 0.7889003440226875 0.7026278346702154 0.8378967763012396 0.9330450414081086 1.0505723989790685 0.9211905699561249 1.0 14.277652048463024 -7.101538245290352 1.824540163582674 0.9908684036908547 0.7142867973662407 0.8892746131126579 0.04315513064126633 0.10436762465183481 0.6880556245139781 0.02034321802618485 0.014402655270042931 7.915197479234e-08 7.101538245290352 -0.27658160632461404 IPSIVSS(ph)PLNSPLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IPSIVSSPLNSPLDR 15 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 IPSIVS(0.421)S(0.578)PLNSPLDR 127.05 2.1878000000000003e-05 2310300.0 4348.9 4236.1 3197.9 3332.1 5859.6 3600.4 3569.1 3981.7 3830.9 2676.2 True False 5085.082875309709 4656.632012590403 3274.150064103288 3145.413239813954 4711.453443490552 3411.5886858580366 3231.009009953682 3877.1845939598766 3886.9196651492375 3161.3738752124577 1.6085041111968985 1.47297731821658 1.0356731577290115 0.9949513610131193 1.4903183329348928 1.0791474910979213 1.0220268584134309 1.2264239368712166 1.2295033167780638 1.0 11.626335948192606 -5.1191285509652955 4.389004284948523 1.1454392420110864 1.5799602068361318 0.5612436075041584 0.14512605058401712 0.16121335869669173 4.913981065339344 0.037953603206790386 0.11419750419995897 7.601012540196935e-06 5.1191285509652955 0.43452096482504543 IPSIVSS(ph)PLNSPLDR ddPTM_PC-9_Lapatinib_30min_R1 1 IPSIVSSPLNSPLDR 15 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 IPSIVS(0.314)S(0.686)PLNSPLDR 139.0 5.6964e-05 6833500.0 20798.0 24778.0 21479.0 22739.0 23352.0 21417.0 23137.0 19206.0 24435.0 18189.0 True False 20501.416706113923 24720.628063355776 19713.079531337706 24411.30191508033 21978.48127179845 20501.04483546544 24334.920649789554 20098.380874950122 21682.872988042844 21332.94441468096 0.9610214280596544 1.1588005660551701 0.9240674493002246 1.144300638512933 1.0302600918358575 0.961003996305216 1.1407202014290483 0.9421287790502454 1.016403200915907 1.0 14.38079548256004 -7.807880555423236 24.999995903451655 0.9844495978266484 1.045345189976618 0.10417895277305289 0.07998403701375426 285.3335666176561 153595.64143221846 0.04041843111709795 0.019416478938980863 1.5563936297121793e-08 7.807880555423236 0.060895592149969535 IPSKEEEADMS(ph)SPTQR ddPTM_PC-9_AZD4547_30min_R2 2 IPSKEEEADMSSPTQR 16 1 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 IPSKEEEADMS(0.727)S(0.273)PTQR;IPS(0.015)KEEEADMS(0.89)S(0.092)PT(0.003)QR 188.0 9.590400000000001e-08 44876000.0 74526.0 62424.0 88522.0 113766.0 91206.0 78149.0 71088.0 96223.0 83035.0 88005.0 True False 98223.71776290139 82601.33723214694 87348.14044075264 87539.00636717872 78543.62123015772 73262.33067597348 77414.69428429622 81353.94633456947 87424.06058068776 84923.97173663719 1.1566076780712615 0.9726504253511232 1.0285451640395857 1.0307926557963065 0.9248698526928774 0.8626813981707271 0.9115764689429688 0.9579621003461903 1.0294391417749955 1.0 16.373884224541648 -1.5228787730835596 0.7380775005410742 0.9504001927905986 31.807807655026682 0.5070293592060886 0.054580912894530494 311.36498957053647 1.413372361333069 0.022320022546926478 15949.044186877145 0.029999998079421525 1.5228787730835596 30.857407462236083 IPSKEEEADMS(ph)SPTQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IPSKEEEADMSSPTQR 16 1 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 IPSKEEEADMS(0.499)S(0.499)PT(0.001)QR;IPSKEEEADMS(0.664)S(0.335)PTQR 114.06 0.00043289 55387000.0 45277.0 47361.0 53359.0 73123.0 80714.0 81557.0 93624.0 88197.0 98335.0 70361.0 True False 52941.50183848733 52062.687082055185 54631.2809251344 69026.1553779645 64898.67111029703 77280.00734710704 84755.25694093858 85881.92220244589 99772.96334345703 83116.8923226303 0.6369523734475923 0.6263791345803245 0.6572825258321153 0.8304708399109708 0.7808120503156374 0.9297749854161228 1.0197115721308339 1.0332667620570162 1.2003933322744282 1.0 16.342854093529965 -6.618411486146937 0.7196895925565069 1.1029882693142774 0.6152586962860217 0.893099103635576 0.060914809835691024 0.20447333296059828 0.23567266109958898 0.041055564429189444 0.048196416048220725 2.40762316836041e-07 6.618411486146937 -0.4877295730282557 IPSKEEEADMS(ph)SPTQR ddPTM_PC-9_Lapatinib_30min_R1 2 IPSKEEEADMSSPTQR 16 1 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 IPSKEEEADMS(0.712)S(0.288)PTQR;IPS(0.011)KEEEADMS(0.865)S(0.124)PTQR 174.4 2.8024e-05 32228000.0 99272.0 88888.0 103912.0 85152.0 131305.0 137338.0 141972.0 125755.0 169299.0 119042.0 True False 97856.36307574494 88682.1852972625 95368.75647191954 91414.36213874487 123581.89805556241 131464.3738905147 149322.61548566882 131598.03639119814 150230.76382249512 139618.25108650542 0.7008851802270075 0.6351761650582224 0.6830679780742308 0.6547450739954181 0.8851414273839663 0.9415987728499857 1.0695064171313156 0.9425561154584434 1.0760109273207723 1.0 17.09112801935774 -6.483977122228482 1.8779414714462919 1.0133930430848566 0.6613556725635026 0.9278039079083299 0.044439682189126035 0.07718052827942994 0.5457604861930081 0.015378794360613204 0.01718166345672292 3.2811257697734295e-07 6.483977122228482 -0.352037370521354 IPSKEEEADMSS(ph)PTQR ddPTM_PC-9_AZD4547_30min_R2 2 IPSKEEEADMSSPTQR 16 1 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 IPS(0.001)KEEEADMS(0.076)S(0.864)PT(0.059)QR;IPSKEEEADMS(0.104)S(0.566)PT(0.331)QR 101.04 0.0021411 187911000.0 115263.0 101835.0 145636.0 200741.0 195394.0 153855.0 143546.0 173823.0 153667.0 160344.0 True False 151914.23638066332 134751.17225803656 143704.77148312808 154463.26386753342 168266.91584594635 144234.42252814345 156321.3159145508 146962.64940517192 161789.52390260188 154730.40536491494 0.9817995113655265 0.8708771358818617 0.9287429393351352 0.9982735035382897 1.087484489225676 0.932165996644177 1.010281822411593 0.9497981282901469 1.0456220516002577 1.0 17.239397196491865 -5.750847197337667 5.572451441202807 1.0023654744543256 0.9205538329710458 0.34424184789132106 0.048075896894698204 0.1760724740845436 17.2253241188439 0.01300759971772774 0.021545698066540317 1.7748138235545897e-06 5.750847197337667 -0.0818116414832798 IPSKEEEADMSS(ph)PTQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IPSKEEEADMSSPTQR 16 1 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 IPS(0.001)KEEEADMS(0.373)S(0.616)PT(0.01)QR;IPSKEEEADMS(0.257)S(0.445)PT(0.298)QR 88.95100000000001 0.008407799999999998 75289100.0 42299.0 39792.0 44673.0 62598.0 73087.0 72155.0 69947.0 74392.0 69202.0 58619.0 True False 49459.38525666841 43742.28678383353 45738.17374329594 59090.83700545423 58766.12700941945 68371.0647783821 63321.11378757396 72439.28882483933 70213.94833267844 69246.1606722514 0.7142545489383063 0.631692592905907 0.6605156632405806 0.8533445960294713 0.8486553830408745 0.9873625355489208 0.9144350123218926 1.046112710388397 1.0139760479286017 1.0 16.07944646323613 -6.200995630725443 0.9516626688849018 1.0054696809541956 0.6454679231813808 0.8932266407908922 0.04734881332082347 0.1679548337773876 0.32035264561904503 0.02188163258542108 0.03737443100252383 6.295125161156168e-07 6.200995630725443 -0.36000175777281485 IPSKEEEADMSS(ph)PTQR ddPTM_PC-9_Lapatinib_30min_R1 4 IPSKEEEADMSSPTQR 16 1 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 IPSKEEEADMS(0.238)S(0.762)PTQR;IPSKEEEADMS(0.288)S(0.544)PT(0.168)QR;IPSKEEEADMS(0.091)S(0.909)PTQR;IPSKEEEADMS(0.125)S(0.751)PT(0.125)QR 223.68 7.279999999999999e-28 97198700.0 121582.0 97699.0 109066.3 105698.4 143501.0 178772.0 138050.0 156372.0 179170.0 129134.0 True False 119848.21838459192 97472.7839681089 100099.28982209295 113471.81293552618 135060.5533138211 171126.33829788642 145197.55351616224 163637.61398405186 158989.98785625695 151454.639839761 0.7913142741047177 0.6435774042395472 0.6609192688186906 0.7492131839313695 0.8917557986781729 1.129885082945878 0.9586867306923132 1.0804397551450418 1.0497531671823879 1.0 17.20852625046563 -6.399506230497295 2.4883653646577897 1.0432493714466686 0.6966922863879952 0.8748382342404436 0.059051681426763994 0.09004928020624553 1.090287642725162 0.01940277044719134 0.022459407458532612 3.985600544301284e-07 6.399506230497295 -0.34655708505867344 IPSKEEEADMSSPT(ph)QR ddPTM_PC-9_AZD4547_30min_R2 1 IPSKEEEADMSSPTQR 16 1 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 IPSKEEEADMS(0.083)S(0.16)PT(0.757)QR 82.367 0.0046321999999999995 20708000.0 42991.0 39696.0 51670.0 66658.0 44077.0 42340.0 56396.0 48917.0 47501.0 37666.0 True False 56661.24373164932 52526.955702411 50984.82203942176 51291.02795583387 37957.6693744014 39692.473106766745 61415.134746471536 41358.00165083338 50011.8058847865 36347.32480463811 1.5588834676608454 1.4451395249784182 1.4027118175397553 1.4111362591749494 1.0443043491761406 1.0920328612933234 1.6896741390616632 1.1378554507966396 1.3759418651466953 1.0 15.14956156396641 -1.5228787454611732 0.03197813155921414 6.298672467631078e-13 3.2745471157045367 0.2784215563598863 0.18823404192959628 1804.8094458084443 4.436636125706882 140.7026125789572 360.79698849979684 0.029999999987508318 1.5228787454611732 3.274547115703907 IPSKEEEADMSSPT(ph)QR ddPTM_PC-9_Lapatinib_30min_R1 1 IPSKEEEADMSSPTQR 16 1 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 IPSKEEEADMS(0.033)S(0.355)PT(0.612)QR 68.625 0.016513999999999997 35923000.0 39396.0 28245.0 54588.0 37855.0 53255.0 61718.0 55983.0 46593.0 58800.0 51676.0 True False 38834.20581565843 28179.600437867626 50099.98535577366 40638.98298057809 50122.64560335843 59078.46501168498 58881.52581307722 48757.880876109055 52177.32480855001 60608.12774605825 0.6407425416335201 0.46494754888217665 0.8266215641190466 0.6705203491988929 0.8269954454519219 0.9747614257153364 0.9715120397677468 0.8044775954868546 0.8608964960469918 1.0 15.887223656294852 -5.812999549223655 0.942203215146661 0.9137070955532167 0.5480272855271795 0.6529781936941977 0.09486653350187527 0.42950425955664956 0.7244512050219447 0.03981378229037619 0.11543827243554587 1.5381562368328462e-06 5.812999549223655 -0.3656798100260372 IPSLGWS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 1 IPSLGWSPSK 10 0 Q8IVF2-3;Q8IVF2 Q8IVF2-3 AHNAK2 Protein AHNAK2 1 IPSLGWS(0.971)PS(0.029)K 96.82 0.0053835 6218000.0 22143.0 22380.0 30672.0 36567.0 37365.0 34705.0 29738.0 32410.0 29962.0 34430.0 True False 29184.013396988015 29613.897335246827 30265.269239271234 28137.043104518245 32177.514716848 32534.890863730285 32384.624389860473 27401.779207709184 31545.730151364674 33224.61617967639 0.8783852682951375 0.8913239862605771 0.9109290856995543 0.8468733830469279 0.9684841667646139 0.9792405332174157 0.9747177880017244 0.8247432885160294 0.9494686102848436 1.0 15.019964912719043 -6.269069648036055 24.984147599227686 0.9434332384596965 0.8846277311402787 0.32332036205137415 0.0473422910932449 848.1465591910509 2777122.2953728097 0.015285905866893183 0.017652189599760153 5.381834668276424e-07 6.269069648036055 -0.058805507319417805 IPSLGWS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IPSLGWSPSK 10 0 Q8IVF2-3;Q8IVF2 Q8IVF2-3 AHNAK2 Protein AHNAK2 1 IPSLGWS(0.96)PS(0.04)K;IPS(0.046)LGWS(0.934)PS(0.02)K 129.74 0.00023622 10489700.0 24346.0 29664.0 36999.0 36054.0 42840.0 35096.0 34806.0 36771.0 31682.0 20775.0 True False 28467.296944581412 32608.845877453707 37881.19647948889 34034.011268645096 34445.80952951317 33255.503977023014 31508.923706381982 35805.80021209495 32145.289313544625 24541.343045190475 1.159973066354261 1.3287311056044373 1.543566560710813 1.3868031267064236 1.4035829035959684 1.355080849315633 1.2839119541404638 1.4589992139453039 1.3098423038361116 1.0 14.582926583383866 -9.894534909166971 10.62939129988478 1.000000034924524 1.3662396754868753 0.5463026590900435 0.09792975640750422 0.0 0.0 0.09598689856968272 0.023280242439897098 1.2748676202733684e-10 9.894534909166971 0.36623964056235137 IPSLGWS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 2 IPSLGWSPSK 10 0 Q8IVF2-3;Q8IVF2 Q8IVF2-3 AHNAK2 Protein AHNAK2 1 IPSLGWS(0.933)PS(0.067)K;IPSLGWS(0.991)PS(0.009)K 136.53 0.00011552 9741200.0 37660.0 55141.0 58853.0 62852.0 56039.0 45973.0 45741.0 42152.0 58616.0 45523.0 True False 37122.96149400183 55013.32440235294 54014.33351914976 67474.34574812574 52742.896196912996 44006.841958297286 48109.24516756812 44110.535803441526 52014.04882615594 53391.58989441539 0.6952960488236891 1.0303743438085402 1.0116637025787372 1.2637635605450168 0.9878502644557838 0.8242279738311422 0.9010641050904576 0.8261701120096325 0.974199287359983 1.0 15.704324889755037 -6.580031129265317 9.033873828567675 0.8949908458189413 1.0184157223225119 0.09332418678928378 0.13852009356010836 0.6403268066136638 94.23039722589054 0.04675056649724292 0.04675989175578235 2.630079466875545e-07 6.580031129265317 0.12342487650357059 IPSTENSSQEISVEERT(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 2 IPSTENSSQEISVEERTPTK 20 1 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 IPSTENSSQEISVEERT(0.655)PT(0.345)K;IPSTENSS(0.001)QEIS(0.01)VEERT(0.731)PT(0.258)K 77.89399999999999 0.0013620999999999998 59726000.0 44728.0 32226.0 48135.0 67219.0 49448.0 49367.0 49191.0 52723.0 46574.0 47713.0 True False 58950.573599804855 42642.42428622269 47496.69844914973 51722.69807319751 42582.99873460987 46280.07368591764 53568.90370440604 44575.87180401269 49035.80655729453 46042.582392706914 1.2803489842729272 0.9261518809374427 1.031581983044312 1.1233665747078148 0.9248612158938105 1.0051580793445754 1.1634643610452937 0.9681444759943233 1.0650099105879374 1.0 15.490681131800454 -4.74697088870314 24.998379625296415 1.0262435094815228 1.2803496400169643 0.5213817927643554 0.07389135775714567 629.2176413763913 1087088.8744824957 0.018028145046333925 0.3857835515765909 1.790725884585651e-05 4.74697088870314 0.2541061305354415 IPSTENSSQEISVEERT(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IPSTENSSQEISVEERTPTK 20 1 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 IPSTENS(0.001)S(0.002)QEIS(0.004)VEERT(0.693)PT(0.299)K;IPSTENSSQEIS(0.001)VEERT(0.899)PT(0.1)K 61.806999999999995 0.0080322 39938000.0 20548.9 21862.7 25756.2 32701.0 29455.5 29044.0 32572.0 34643.0 26600.0 21230.8 True False 24027.422910724938 24033.084370449265 26370.32548893243 30868.86898807242 23683.90622307597 27520.881510960135 29486.544359141335 33733.65795729259 26988.974677744052 25079.775977079666 0.9580397740667034 0.9582655121167363 1.0514577766975348 1.230827142008102 0.9443428140953342 1.0973336259507018 1.1757100376849061 1.3450541977775912 1.0761250300803802 1.0 14.614236840998824 -4.867662793291917 0.605000751187613 1.1512397704390556 0.8066953353995198 0.22811704953197287 0.11031251023972569 4.628549073956866 1.3804967760426052 0.058541000155000036 1.1001244998362882 1.3562420539008283e-05 4.867662793291917 -0.3445444350395358 IPSTENSSQEISVEERT(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 3 IPSTENSSQEISVEERTPTK 20 1 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 IPSTENSS(0.001)QEIS(0.002)VEERT(0.797)PT(0.2)K;IPSTENSS(0.001)QEIS(0.002)VEERT(0.965)PT(0.032)K;IPSTENSSQEIS(0.041)VEERT(0.722)PT(0.237)K 67.655 0.0039222 67995100.0 73562.0 62300.0 89909.0 68878.0 78366.0 69990.0 58454.0 61379.0 85134.0 54358.0 True False 72512.99239038152 62155.74817770055 82517.02907877645 73943.51789027243 73756.665953484 66996.6908546587 61480.46210238134 64230.892415055874 75545.31241923629 63753.70787251787 1.1373925503341507 0.9749354233950972 1.294309489320649 1.159830860945847 1.1569000206382989 1.0508673627050131 0.9643433167105806 1.0074848123891427 1.184955588313341 1.0 15.960221630128538 -6.8090414524036165 5.848385620476199 1.036028899263355 1.1444409696986992 0.24646499784546272 0.09009914284358907 0.2914329984106819 22.744929351614594 0.032612033494754236 0.029152080174695623 1.5522388452803183e-07 6.8090414524036165 0.10841207043534418 IPTYNT(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 1 IPTYNTPLK 9 0 Q02241;H7BYN4 Q02241 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 IPT(0.001)YNT(0.999)PLK 89.561 0.022619 11252000.0 57276.0 50000.0 62969.0 56278.0 59291.0 76746.0 51997.0 51353.0 76627.0 47861.0 True False 56459.233736867965 49884.22807199086 57791.93188736919 60416.87185790447 55803.619950590975 73463.75248366395 54689.150236725 53739.04785334343 67996.4603419178 56133.71007922621 1.0057990761198985 0.8886679323633707 1.0295405702883809 1.0763028449862493 0.9941195739927157 1.308727899509553 0.9742657337193215 0.9573400328874931 1.211330237141794 1.0 15.77657979491582 IPVEGPLS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 1 IPVEGPLSPSR 11 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 IPVEGPLS(0.725)PS(0.275)R 136.01 7.726e-05 15740000.0 6581.7 6716.4 9199.0 6177.8 9232.2 8656.9 8106.7 9081.8 11691.0 6236.8 True False 6487.8437510640415 6700.848588454388 8442.693729166886 6632.136020536668 8689.180147203559 8286.664567219535 8526.425259612257 9503.773582740918 10374.23646831221 7314.822569986376 0.8869447876541078 0.916064405437365 1.154189817782909 0.9066707985165826 1.1878866594599768 1.1328592714224877 1.1656366477838078 1.2992486819483604 1.4182485452044988 1.0 12.83660715510852 -6.193903717875294 0.6900725288198652 1.2515080807818404 0.903754762562405 0.44779633209359615 0.12504758835329707 0.7484122678830052 0.7473970667160614 0.07591737160602287 0.15244891894477203 6.398766790013225e-07 6.193903717875294 -0.34775331821943545 IPVEGPLS(ph)PSRGDFPK ddPTM_PC-9_AZD4547_30min_R2 1 IPVEGPLSPSRGDFPK 16 1 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 IPVEGPLS(0.982)PS(0.018)RGDFPK 70.837 0.0089924 10659000.0 33803.0 24123.0 37258.0 59705.0 55035.0 34849.0 28571.0 41190.0 23384.0 43267.0 True False 44551.6508539216 31920.287999024094 36763.93457605525 45940.9346830547 47394.34022324978 32669.8865209663 31113.76365063904 34825.031952037694 24620.030500617846 41752.23549944986 1.067048274684804 0.7645168604072634 0.8805261355775709 1.1003227523867563 1.1351329972229693 0.7824703547046425 0.7451999462651289 0.8340878406976929 0.5896697555497896 1.0 15.34956582402544 -6.852712311533593 11.194678268522226 0.7765383125673436 0.9770331027653831 0.3369083873136547 0.13854227970141433 0.5304717889449603 61.42536031896201 0.04992123219396228 0.04403381486763528 1.403743274332311e-07 6.852712311533593 0.2004947901980395 IPVEGPLS(ph)PSRGDFPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IPVEGPLSPSRGDFPK 16 1 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 IPVEGPLS(0.917)PS(0.083)RGDFPK;IPVEGPLS(0.774)PS(0.226)RGDFPK 56.818999999999996 0.028325 16612600.0 60254.0 32152.0 47969.0 74747.0 79011.0 87368.0 79633.0 87113.0 77947.0 65290.0 True False 70453.81212925368 35343.83807483454 49112.762883445575 70559.16792304354 63529.361735209284 82786.26827742609 72089.58574700673 84826.37605385305 79086.8274137638 77126.56016464437 0.913483137052318 0.4582576741317776 0.636781450885442 0.9148491488848819 0.823702776314557 1.0733820891363464 0.9346920904175544 1.0998335187355905 1.0254162411098693 1.0 16.234940147850786 -6.162385920390556 1.3254361070573124 1.0249725720794365 0.6510703025810741 0.5673614285531386 0.12585972139413518 0.2953279405027755 1.0503447378245856 0.046633015206169776 0.07266975159379525 6.880406217135925e-07 6.162385920390556 -0.37390226949836236 IPVEGPLS(ph)PSRGDFPK ddPTM_PC-9_Lapatinib_30min_R1 1 IPVEGPLSPSRGDFPK 16 1 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 IPVEGPLS(0.761)PS(0.239)RGDFPK 125.61 0.00015035 2925500.0 24914.0 14744.0 15139.0 14717.0 14016.0 17736.0 13069.0 12719.0 17917.0 11950.0 True False 24558.721791331955 14709.861173868667 13894.329858229969 15799.337274472808 13191.60643651623 16977.472624635342 13745.648872891881 13309.971172992326 15898.998785625701 14015.541577625896 1.7522492195761425 1.0495392627104163 0.9913516207187151 1.1272726913167967 0.9412127503923945 1.2113319011330828 0.9807433267391632 0.9496579992484966 1.1343834769115533 1.0 13.774739872493466 -4.761488670402262 8.349199805353974 1.0419829021905749 1.7594788824019054 0.8640964083671352 0.08440753180324362 0.028266749173661093 20.274174106105406 0.019786897731632808 0.11461384354152143 1.731854209670004e-05 4.761488670402262 0.7174959802113305 IPVEGPLSPS(ph)R ddPTM_PC-9_AZD4547_30min_R2 4 IPVEGPLSPSR 11 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 IPVEGPLS(0.316)PS(0.684)R;IPVEGPLS(0.285)PS(0.715)R;IPVEGPLS(0.232)PS(0.768)R;IPVEGPLS(0.234)PS(0.766)R 104.94 0.0026206999999999997 58680000.0 37499.1 42528.5 75923.3 76488.8 73958.0 78470.8 56487.7 92198.0 72816.5 71720.1 True False 49423.03377026569 56275.00593485455 74916.50743459699 58855.48890017984 63690.208308005946 73564.0084711023 61514.9958688251 77950.91759927105 76665.43153216901 69209.20112889932 0.7141107390940303 0.8131145139219949 1.082464559807128 0.8503997725759597 0.9202563715391762 1.0629223755103359 0.8888268447753922 1.1263085879880428 1.1077346694030286 1.0 16.078676231581966 -3.646240836457161 0.4530645721010907 1.0395085493657765 2.09215813859791e-21 0.5245714876768265 0.09179963476707831 11.379253338484295 0.8179227740220317 0.06180959182610548 7.890140288077306 0.00022581831555155965 3.646240836457161 -1.0395085493657765 IPVEGPLSPS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 IPVEGPLSPSR 11 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 IPVEGPLS(0.042)PS(0.958)R 101.38 0.0037575000000000004 15079000.0 6610.9 8952.8 12577.0 6550.2 9990.3 12691.0 9028.0 10954.0 13005.0 8027.8 True False 6516.6273537094185 8932.070341658391 11542.96760862397 7031.923558826646 9402.690195685502 12148.235514165945 9495.425665656738 11462.962829543045 11540.239951278794 9415.39453362889 0.6921247251439153 0.9486666023134543 1.2259674905173696 0.7468538396039358 0.9986506844829484 1.2902524127667925 1.0085000295783677 1.2174702598601546 1.2256777886535302 1.0 13.20080583407241 -6.547701065042704 12.34530748956096 1.1523179811845294 0.9225638795027371 0.34848581532173717 0.15787598994630345 1.0772952190916472 532.4310260849273 0.051698429819422444 0.05181935273813767 2.833341579426513e-07 6.547701065042704 -0.22975410168179233 IPYQS(ph)PVSSSESAPGTIMNGHGGGR ddPTM_PC-9_AZD4547_30min_R2 1 IPYQSPVSSSESAPGTIMNGHGGGR 25 0 Q5T6F2;H0YDN2 Q5T6F2 UBAP2 Ubiquitin-associated protein 2 1 IPY(0.011)QS(0.7)PVS(0.183)S(0.074)S(0.03)ES(0.001)APGTIMNGHGGGR 70.083 0.00034365 7532300.0 1813.5 3437.7 5979.8 8694.0 7268.0 7425.0 5977.0 6656.5 4786.6 5374.6 True False 2390.155276856693 4548.869297112508 5900.503944868091 6689.732620961019 6258.963654812022 6960.713576233889 6508.941421016745 5627.890876152924 5039.609903962426 5186.436889900921 0.4608472690588072 0.8770702109515898 1.1376796961238664 1.2898513493892751 1.2067945272793223 1.3420993495144724 1.2549928899532194 1.0851170072292995 0.9716902009885827 1.0 12.340528024278957 -4.860056251970698 1.8849749919903562 1.183037440560091 0.3048196060048536 0.7813389156678392 0.1147723534386815 0.3106210039456931 1.339005469256923 0.03336533063804071 0.46061584983517895 1.3802054819798179e-05 4.860056251970698 -0.8782178345552374 down IPYQS(ph)PVSSSESAPGTIMNGHGGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IPYQSPVSSSESAPGTIMNGHGGGR 25 0 Q5T6F2;H0YDN2 Q5T6F2 UBAP2 Ubiquitin-associated protein 2 1 IPY(0.009)QS(0.859)PVS(0.082)S(0.037)S(0.011)ES(0.002)APGTIMNGHGGGR;IPY(0.001)QS(0.984)PVS(0.006)S(0.006)S(0.003)ES(0.001)APGTIMNGHGGGR 78.268 7.9519e-05 10666800.0 11142.3 10762.2 19936.1 22418.9 21641.0 21139.2 20214.1 16928.2 17680.9 13918.9 True False 13028.471319543649 11830.600091098038 20411.452232080283 21162.841716054474 17400.601401218366 20030.62313856524 18299.274110589442 16483.852686910508 17939.44971352349 16442.28638804822 0.7923758905582592 0.7195228091695093 1.2413998728861226 1.287098473813082 1.0582835616989825 1.2182383073637106 1.1129397505137153 1.0025280120952342 1.091055665260979 1.0 14.005123306996467 -5.254682491386597 24.997676319632458 1.1326328243359993 0.7559493054711052 0.7140351910090998 0.09372034922872635 277.18715388749007 1025470.5116068273 0.025047306977626888 0.06317112089853939 5.563108222472676e-06 5.254682491386597 -0.37668351886489415 IPYQS(ph)PVSSSESAPGTIMNGHGGGR ddPTM_PC-9_Lapatinib_30min_R1 3 IPYQSPVSSSESAPGTIMNGHGGGR 25 0 Q5T6F2;H0YDN2 Q5T6F2 UBAP2 Ubiquitin-associated protein 2 1 IPY(0.015)QS(0.931)PVS(0.05)S(0.003)S(0.001)ES(0.001)APGTIMNGHGGGR;IPY(0.037)QS(0.951)PVS(0.009)S(0.003)SESAPGTIMNGHGGGR;IPY(0.001)QS(0.802)PVS(0.118)S(0.051)S(0.022)ES(0.007)APGTIMNGHGGGR 76.749 9.871700000000001e-05 10390300.0 31118.0 28898.7 34136.4 21419.2 31702.5 32564.0 25889.8 24172.8 34145.3 20720.8 True False 30674.251613657696 28831.786835680847 31329.83696231464 22994.439420356597 29837.82127951311 31171.313630391585 27230.247164235698 25295.95653514498 30299.496748050737 24302.362671269515 1.2621921591978005 1.1863779347580086 1.2891683572541313 0.9461812306644919 1.2277745041961565 1.2826453975704433 1.1204773598588238 1.0408846611877 1.2467716475925648 1.0 14.56880895874783 -14.522878743720185 0.11686983671032554 0.45682931171851476 1.2593711050040186 0.21302899441208256 0.10573282733122315 263.427575897706 2.0046455180548306 34.182973136529434 1.1151299452555783 3.0000000107771556e-15 14.522878743720185 0.8025417932855039 IPYQSPVS(ph)SSESAPGTIMNGHGGGR ddPTM_PC-9_AZD4547_30min_R2 1 IPYQSPVSSSESAPGTIMNGHGGGR 25 0 Q5T6F2;H0YDN2 Q5T6F2 UBAP2 Ubiquitin-associated protein 2 1 IPY(0.002)QS(0.191)PVS(0.537)S(0.221)S(0.039)ES(0.01)APGTIMNGHGGGR 76.711 9.9194e-05 6797600.0 4930.6 4963.6 11316.0 15926.0 14536.0 12321.0 7181.4 15553.0 9035.3 12767.0 True False 6498.428237148944 6567.986631511671 11165.942446256942 12254.506754247208 12517.927309624043 11550.565922259639 7820.530687784784 13149.641222385093 9512.887512069467 12320.031215972362 0.527468487963247 0.5331144472261218 0.9063242008494917 0.9946814695047035 1.0160629539148502 0.9375435597342362 0.6347817266603855 1.0673383039271183 0.7721480039544413 1.0 13.588718291026376 -5.26319228080127 6.752894617485716 0.9161106590235079 0.5281476935118194 0.619390113856653 0.1210016986970085 0.07994899529238181 23.231680947596267 0.031173461950888933 0.07343107584567225 5.455162841516956e-06 5.26319228080127 -0.3879629655116884 IQAAAS(ph)TPTNATAASDANTGDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IQAAASTPTNATAASDANTGDR 22 0 P49841;P49841-2 P49841 GSK3B Glycogen synthase kinase-3 beta 1 IQAAAS(0.677)T(0.285)PT(0.038)NATAASDANTGDR 216.31 2.2032999999999997e-93 0.0 10807.0 11429.0 12970.0 12734.0 15808.0 12341.0 16744.0 10122.0 11808.0 11351.0 True False 12636.411652020519 12563.595588370355 13279.253988998908 12020.555264185026 12710.535878677501 11693.816234911132 15157.887103937815 9856.308225145509 11980.669661458714 13408.846445533445 0.9423936431332445 0.9369631936202352 0.990335301618902 0.8964645328002196 0.9479216523440348 0.8720971100990124 1.1304393085198603 0.735060116109294 0.8934899590448764 1.0 13.710897508000453 -7.782975163113892 24.999963982366115 0.8607064571198756 0.9536011050337535 0.1466878218080887 0.08901004101106062 407.27707941370306 472783.67077413737 0.04544842329066124 0.021864238617159287 1.6482566510518378e-08 7.782975163113892 0.09289464791387791 IQAAAST(ph)PTNATAASDANTGDR ddPTM_PC-9_AZD4547_30min_R2 2 IQAAASTPTNATAASDANTGDR 22 0 P49841;P49841-2 P49841 GSK3B Glycogen synthase kinase-3 beta 1 IQAAAS(0.051)T(0.948)PT(0.002)NATAASDANTGDR;IQAAAS(0.018)T(0.923)PT(0.056)NAT(0.004)AASDANTGDR 157.02 1.3752e-05 10572000.0 26478.0 27515.0 32554.0 44794.0 41911.0 48480.0 36107.0 52283.0 41825.0 40775.0 True False 34897.45322338657 36408.68566484879 32122.312689594255 34467.43536040119 36092.38108651988 45448.537936137254 39320.453051472585 44203.86369381853 44035.78411257016 39347.47966094407 0.8869044097384832 0.9253117602088172 0.8163753553312986 0.8759756827478137 0.9172730095428409 1.1550558848435988 0.9993131298445448 1.1234230012880562 1.119151327912869 1.0 15.263983608748374 -6.642330506106199 5.594675716561723 1.081408967787632 0.8780581099760131 0.7717991758168214 0.053302374267211364 0.09546364934360915 4.305890196666352 0.01733076532345884 0.017270935259856516 2.2786073498109512e-07 6.642330506106199 -0.20335085781161888 IQAAAST(ph)PTNATAASDANTGDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IQAAASTPTNATAASDANTGDR 22 0 P49841;P49841-2 P49841 GSK3B Glycogen synthase kinase-3 beta 1 IQAAAS(0.005)T(0.978)PT(0.016)NAT(0.001)AASDANTGDR 238.49 9.041799999999998e-126 0.0 8374.0 14311.0 14922.0 18306.0 19202.0 14879.0 16906.0 10305.0 14354.0 13177.0 True False 9791.552805960937 15731.701501895897 15277.797072000134 17280.37416885275 15439.505942710355 14098.719047017488 15304.541291159398 10034.504669050035 14563.90009489994 15565.885790925386 0.6290392295997203 1.0106525072326549 0.9814923016399618 1.1101439648829288 0.9918809729229346 0.9057447315485748 0.9832104318844259 0.6446471986130053 0.9356293814895145 1.0 13.926100056569446 IQAAAST(ph)PTNATAASDANTGDR ddPTM_PC-9_Lapatinib_30min_R1 2 IQAAASTPTNATAASDANTGDR 22 0 P49841;P49841-2 P49841 GSK3B Glycogen synthase kinase-3 beta 1 IQAAAS(0.097)T(0.864)PT(0.038)NAT(0.001)AASDANTGDR;IQAAAS(0.001)T(0.371)PT(0.371)NAT(0.253)AAS(0.003)DANTGDR 275.65 7.619299999999999e-101 11549900.0 17841.2 28791.0 32805.0 29730.0 50767.0 47717.0 45877.0 49107.0 40657.0 38328.0 True False 17586.781216324624 28724.336208413766 30107.89953096202 31916.44337637268 47780.98487176221 45676.255143759845 48252.28658211499 51388.690493917304 36077.78052280983 44952.94373115025 0.39122646386643245 0.6389867675897979 0.6697648036361783 0.7099967371937893 1.0629111445409583 1.0160904126086936 1.0733954792971312 1.1431663029958012 0.8025676969806461 1.0 15.456127972870382 -5.8798584243895515 1.2323759689564324 1.0339078113800286 0.5014670380678836 0.7878153834721265 0.10710114122110086 0.21050064548227423 0.6438047897565634 0.03844555095041505 0.0851795881146138 1.3186865469785927e-06 5.8798584243895515 -0.532440773312145 IQASTMAFK ddPTM_PC-9_Lapatinib_30min_R1 1 IQASTMAFK 9 0 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 0 93.111 0.029991000000000004 4651000.0 35332.0 35407.0 39614.0 31634.0 34586.0 32064.0 34655.0 34799.0 26990.0 36198.0 False True 34828.15920090475 35325.01726689957 36357.0898344621 33960.469887930456 32551.719478692226 30692.697464834662 36449.26633178269 36415.88857999527 23950.1019827001 42454.776069196836 0.8203590367344891 0.8320622680784724 0.8563721965039659 0.79992106971848 0.7667386921470587 0.7229504029136505 0.8585433655891672 0.8577571701389071 0.5641321000884316 1.0 15.373639242485657 -5.919059047112234 6.034316757522334 0.7871192950645363 0.835464568466253 0.02720911529627712 0.10504859194692213 0.7860819605500683 45.81170949381308 0.02849230913997165 0.042633559642919025 1.2048721136170864e-06 5.919059047112234 0.04834527340171679 IQDPTEDAEAEDT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 IQDPTEDAEAEDTPR 15 0 O96028;O96028-3;H0Y9L4;O96028-5 O96028;O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 IQDPTEDAEAEDT(1)PR;IQDPTEDAEAEDT(1)PR 164.82 0.00072581 76522000.0 67557.0 68329.0 92991.0 94871.0 98884.0 85409.0 86066.0 104536.0 88248.0 86518.0 True False 89038.7207271066 90415.01300357823 91757.87858076004 72999.95669233872 85155.6634620848 80068.36172829117 93725.70726806545 88382.3631983058 92912.60911813738 83489.03115402984 1.0664720801806655 1.0829567879015216 1.0990411232761212 0.8743658380423686 1.0199622906748094 0.9590285169386163 1.1226110301262193 1.058610478246516 1.1128720483858756 1.0 16.349299047325722 -7.269639616627064 24.952546709503906 1.078407591607794 1.0173548154330028 0.1390588847390023 0.06850168162448242 1246.8143761760173 3793919.54172554 0.029522011683553395 0.0202850653813332 5.374776174901771e-08 7.269639616627064 -0.06105277617479121 IQDPTEDAEAEDT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IQDPTEDAEAEDTPR 15 0 O96028;O96028-3;H0Y9L4;O96028-5 O96028;O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 IQDPTEDAEAEDT(1)PR;IQDPTEDAEAEDT(1)PR 98.572 0.0054526 46583300.0 81302.0 89510.0 71245.0 78881.0 97350.0 70246.0 82210.0 74373.0 70668.0 61161.0 True False 95064.82281230444 98395.96124901828 72943.75099816713 74461.55330565236 78274.96633282224 66562.17609898443 74422.47365114246 72420.78755470738 71701.38580927892 72249.00514979038 1.3157942121861903 1.3619005693575805 1.0096159919010148 1.0306239255651315 1.0834054554874288 0.9212884794881852 1.0300830232450389 1.0023776438798133 0.9924203891890815 1.0 16.14069010176006 -5.26385083203202 24.970832877092068 1.00990082213915 1.3388474125734338 0.9178032642472238 0.039515844753946705 46.69531534922763 483540.8084795355 0.010204155808870886 0.023017116962250138 5.446897063465901e-06 5.26385083203202 0.32894659043428387 IQDPTEDAEAEDT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 IQDPTEDAEAEDTPR 15 0 O96028;O96028-3;H0Y9L4;O96028-5 O96028;O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 IQDPTEDAEAEDT(1)PR;IQDPTEDAEAEDT(1)PR 218.64 1.4825e-17 94634000.0 82482.0 79866.0 91493.0 95199.0 85617.0 72863.0 78584.0 73121.0 98606.0 78980.0 True False 81305.79155465355 79681.07518395231 83970.79871319338 102200.2520345546 80581.17638949835 69746.81934194894 82652.69500553497 76518.46860133426 87499.95391278717 92631.58776576516 0.8777328934515208 0.8601933433921004 0.9065028543559884 1.1032980703405997 0.8699103441178365 0.7529485462163914 0.8922733270483981 0.8260515710345409 0.9446016852701024 1.0 16.499216622085704 -3.376711128238662 15.445430299883775 0.8975476654146124 0.4212298728476657 0.0 0.09150092551587624 0.0 0.0 0.02171726949203149 0.0 0.0004200382803165099 3.376711128238662 -0.4763177925669467 IQEAGTEVVK ddPTM_PC-9_Lapatinib_30min_R1 2 IQEAGTEVVK 10 0 P40926;G3XAL0;P40926-2 P40926 MDH2 Malate dehydrogenase, mitochondrial;Malate dehydrogenase 0 ; 112.13 0.0068914 4246100.0 47001.0 63792.0 41369.0 51791.0 51465.0 41198.0 57468.0 56905.0 56139.0 50995.0 False True 46330.7571210722 63644.293543368774 37967.800508958026 55599.88290971131 48437.929884083016 39436.05757722861 60443.41184691646 59549.014041915856 49816.034650122296 59809.417803433724 0.7746398280173913 1.0641182589761788 0.6348130763242148 0.9296175243243926 0.8098712821996763 0.6593620039378572 1.0106002376676928 0.9956461077355125 0.8329128836171734 1.0 15.868085053747473 -7.2990663008342755 24.99686248732023 0.9594269937636424 0.8207129002535641 0.25029317712624555 0.12470848501935528 884.756335723781 587770.892134271 0.05089542518688171 0.03431460845741469 5.022659060921046e-08 7.2990663008342755 -0.13871409351007824 IQEQES(ph)SGEEDSDLSPEER ddPTM_PC-9_AZD4547_30min_R2 1 IQEQESSGEEDSDLSPEER 19 0 E7EMN6;Q6NXS1;P41236 E7EMN6 PPP1R2;PPP1R2P3 Protein phosphatase inhibitor 2-like protein 3;Protein phosphatase inhibitor 2 1 IQEQES(0.5)S(0.5)GEEDSDLSPEER 239.13 2.0023999999999995e-118 0.0 13272.0 9687.6 14553.0 16363.0 16271.0 15917.0 10075.0 13134.0 12859.0 12449.0 True False 17492.219925250643 12818.927248656704 14360.01771123872 12590.763155829905 14012.052507904018 14921.707473793242 10971.655482138829 11104.442089295044 13538.700487831202 12013.164299180693 1.4560876293387268 1.067073331339601 1.1953568063843165 1.0480804925550387 1.1663914817896606 1.2421129938937832 0.9133027076710425 0.9243561323849018 1.1269887059444073 1.0 13.552328590330792 -2.550559255655907 1.378481012814659 1.0711687304563038 199.95187245874536 0.5270249724452315 0.10626670912185664 640.6712339795001 3.1049383364563408 0.03187667209849079 400979.897167956 0.002814755940282123 2.550559255655907 198.88070372828906 IQEQESS(ph)GEEDSDLSPEER ddPTM_PC-9_AZD4547_30min_R2 2 IQEQESSGEEDSDLSPEER 19 0 E7EMN6;Q6NXS1;P41236 E7EMN6 PPP1R2;PPP1R2P3 Protein phosphatase inhibitor 2-like protein 3;Protein phosphatase inhibitor 2 1 IQEQES(0.001)S(0.999)GEEDSDLSPEER;IQEQES(0.115)S(0.883)GEEDS(0.001)DLSPEER 200.73 3.3477999999999995e-59 23299000.0 28746.0 31294.0 41221.0 47701.0 37909.0 47253.0 31019.0 40637.0 39244.0 33070.8 True False 37886.630046055965 41409.17351247607 40674.38260667704 36704.27142310345 32645.98970697151 44298.262440105056 33779.63090823464 34357.48539536188 41318.35772178611 31913.001357968093 1.187184797226738 1.2975643703326247 1.2745395567916833 1.1501353636842766 1.0229683300790637 1.3880945243354428 1.0584911938970756 1.0765983747493384 1.2947186401654345 1.0 14.961856677312204 -14.522878744983307 0.09383989193945398 0.42556971094959034 1.3294402452636527 0.2068259058548787 0.11350719631784038 324.81064828687835 2.0935071358074366 37.57151033696487 2.346481077361643 3.0000000020518113e-15 14.522878744983307 0.9038705343140623 IQEQESS(ph)GEEDSDLSPEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IQEQESSGEEDSDLSPEER 19 0 E7EMN6;Q6NXS1;P41236 E7EMN6 PPP1R2;PPP1R2P3 Protein phosphatase inhibitor 2-like protein 3;Protein phosphatase inhibitor 2 1 IQEQES(0.086)S(0.914)GEEDSDLSPEER 298.0 2.0340999999999993e-121 17083000.0 16782.0 19057.0 18363.0 17553.0 19740.0 19431.0 22489.0 20190.0 17336.0 12401.0 True False 19622.86114039126 20948.85301667461 18800.843562065314 16569.562317593827 15872.088704775664 18412.004153679474 20358.679113739716 19660.033893073287 17589.506203510187 14649.20313373802 1.3395173076137226 1.43003362199464 1.2834038404973587 1.131089668586348 1.083477958485077 1.2568604575681999 1.3897465225840455 1.3420548349005426 1.2007141987812613 1.0 13.83853456868353 -8.591394052363693 6.049289550678707 1.0000068800499595 1.277869144603699 0.4131550047571101 0.10168799799540544 0.8090550323432261 70.13466673073295 0.11230217801616298 0.029103510671713597 2.5621582351887116e-09 8.591394052363693 0.2778622645537394 IQEQESS(ph)GEEDSDLSPEER ddPTM_PC-9_Lapatinib_30min_R1 1 IQEQESSGEEDSDLSPEER 19 0 E7EMN6;Q6NXS1;P41236 E7EMN6 PPP1R2;PPP1R2P3 Protein phosphatase inhibitor 2-like protein 3;Protein phosphatase inhibitor 2 1 IQEQES(0.016)S(0.546)GEEDS(0.438)DLSPEER 298.96 1.5705999999999995e-121 30477000.0 13086.0 13578.0 17355.0 13942.0 15929.0 18061.0 16711.0 19769.0 14559.0 15766.0 True False 12899.391240321504 13546.560975229833 15928.138892237339 14967.341189148587 14992.087537618927 17288.573132247344 17576.21381244902 20687.53991028268 12919.212106933326 18491.13209312552 0.6975987827763738 0.7325977072148038 0.8613933864092058 0.8094334686361913 0.8107717505945761 0.9349656389440182 0.9505212403400307 1.1187816844363858 0.6986706947886833 1.0 14.174545933936763 -5.264426357022861 0.4501544375797339 0.9613723113901925 0.5840843003878861 0.38263137540485925 0.10363725822320047 3.454657765432677 0.7497891455240613 0.07870539544146118 0.6658263464045335 5.439683641922551e-06 5.264426357022861 -0.37728801100230647 IQEQESSGEEDS(ph)DLSPEER ddPTM_PC-9_Lapatinib_30min_R1 1 IQEQESSGEEDSDLSPEER 19 0 E7EMN6;Q6NXS1;P41236 E7EMN6 PPP1R2;PPP1R2P3 Protein phosphatase inhibitor 2-like protein 3;Protein phosphatase inhibitor 2 1 IQEQES(0.013)S(0.095)GEEDS(0.891)DLSPEER 186.17 6.674600000000001e-11 15845000.0 27381.0 33517.0 37369.0 35717.0 42135.0 32542.0 32931.0 42279.0 38979.0 38039.0 True False 26990.54191893958 33439.393445778354 34296.66506851147 38343.74732841919 39656.70214059727 31150.254519107108 34636.006047379495 44243.43668707779 34588.77455293317 44613.99046621853 0.6049793268184936 0.7495270675484292 0.7687423767770947 0.8594556758479801 0.8888848929715245 0.6982171779207671 0.7763485329474324 0.9916942247203526 0.775289862921444 1.0 15.44520857425027 -1.825913515940447 0.1084642660914769 1.0519751239286317 8.55074021147978e-18 0.474873581890611 0.08573923942048994 102.51001888610364 0.8346842621757601 0.8847799727100187 16.013594013866076 0.01493091709640199 1.825913515940447 -1.0519751239286317 IQEQSTSPDT(ph)SLGSTTPSSHTLELVALDSEVLR ddPTM_PC-9_AZD4547_30min_R2 1 IQEQSTSPDTSLGSTTPSSHTLELVALDSEVLR 33 0 A0A494C0H4;H0Y9M2;Q17R98-2;Q17R98;A0A5F9ZGW8 A0A494C0H4 ZNF827 Zinc finger protein 827 1 IQEQS(0.009)T(0.015)S(0.023)PDT(0.416)S(0.416)LGS(0.034)T(0.034)T(0.034)PS(0.008)S(0.008)HT(0.002)LELVALDSEVLR 47.23 0.02391 2913600.0 1069.0 971.09 2188.5 3818.9 2859.2 2532.4 2419.1 3247.6 2192.5 3032.8 True False 1408.9197634186949 1284.975851800037 2159.479060059503 2938.511606416843 2462.2494333844984 2374.048627670669 2634.3952135823356 2745.758042423831 2308.3910739225375 2926.6225951124766 0.4814149134813698 0.43906441983533323 0.7378741159402924 1.004062365719523 0.841327965381156 0.8111905619929887 0.9001485938029157 0.9382002472779738 0.7887559802817079 1.0 11.515020998545047 -5.411103240638844 3.434209176296 0.8890330490581008 0.4596137752663417 0.856711556838627 0.07061722851702334 0.07986810661449478 1.7212541901240197 0.018649137657987643 0.042935510077622197 3.880581057139737e-06 5.411103240638844 -0.4294192737917591 IQES(ph)FTSEEER ddPTM_PC-9_AZD4547_30min_R2 1 IQESFTSEEER 11 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q5VWV2;Q8TEW0-6;Q8TEW0-3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 IQES(0.995)FT(0.003)S(0.002)EEER 150.49 0.00033729 4424800.0 5361.3 2414.4 1902.0 6147.9 7296.2 3925.6 5779.3 5325.6 2356.8 4722.9 True False 7066.08187803242 3194.80758383467 1876.7782372552774 4730.596639108149 6283.248571579455 3680.1316114294646 6293.646504012394 4502.650890113424 2481.375636497439 4557.552708538878 1.5504114444565054 0.7009919112617141 0.4117951798426837 1.0379686076356422 1.3786452891279504 0.807479769687467 1.3809267619046577 0.9879536624288313 0.5444535247718401 1.0 12.15404362593098 -4.747971016374119 24.960835486991773 0.9298566801283075 1.5504129932069897 0.28359041025893106 0.30151908961968593 979.2385935534469 1814709.3174342348 0.07908412040086728 1.5203514866867345 1.7866068041250393e-05 4.747971016374119 0.6205563130786822 IQES(ph)PGK ddPTM_PC-9_Lapatinib_30min_R1 1 IQESPGK 7 0 P49736;H0Y8E6 P49736 MCM2 DNA replication licensing factor MCM2 1 IQES(1)PGK 103.55 0.010520999999999999 13559000.0 83335.0 126180.0 113060.0 111510.0 134120.0 117380.0 112570.0 96051.0 118610.0 82774.0 True False 82146.62761823261 125887.83796247604 103764.6432242208 119710.81738645544 126231.32529006542 112359.93102614452 118398.3237907597 100513.88011141495 105250.89278132857 97081.37561057803 0.8461625837250897 1.2967249090850257 1.068841912999372 1.2330976630023327 1.3002630473265686 1.1573788517053287 1.2195781430383745 1.0353569825236686 1.0841512300311944 1.0 16.566906930688873 -7.772995601410044 24.883178158379486 1.0448155204674736 1.1700941422240514 0.15801022100699647 0.12585227755506184 378.8569384934748 815751.5158609311 0.06516452077041149 0.03172665063361657 1.686570107099594e-08 7.772995601410044 0.12527862175657778 IQESFT(ph)SEEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IQESFTSEEER 11 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q5VWV2;Q8TEW0-6;Q8TEW0-3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 IQES(0.297)FT(0.666)S(0.037)EEER 120.53 0.0020965999999999997 3444300.0 10332.0 9683.5 9519.5 10351.0 9532.4 1959.4 6497.2 9084.0 5287.7 2266.4 True False 12081.003533698151 10644.813883977984 9746.480982904795 9771.067028394786 7664.594648905957 1856.645614673437 5881.738180345486 8845.554625293598 5365.022609154406 2677.2803791874717 4.512416266750745 3.975980239771742 3.6404408961689536 3.6496241127200166 2.8628285287146826 0.6934819487366918 2.196907812147242 3.303932861891042 2.003907641075171 1.0 11.386552518329534 -1.5228787452921881 0.20646010178044308 1.3075795080815857 18.24676158421355 0.6396325878467337 0.7271816528363567 37.744794432076354 0.46508682093428655 1.4025925936836168 208.82976630653954 0.02999999999918139 1.5228787452921881 16.939182076131967 IQEVADELQK ddPTM_PC-9_Lapatinib_30min_R1 2 IQEVADELQK 10 0 C9JPM4;C9JAK5;P18085 C9JPM4 ARF4 ADP-ribosylation factor 4 0 ; 124.1 0.0019529 7602400.0 37772.0 36714.0 40218.0 34557.0 38019.0 38097.0 43633.0 35321.0 33532.0 31985.0 False True 37233.364353463556 36628.990988701415 36911.431285969535 37098.43705877262 35782.797168229896 36467.680118444565 45892.1032420913 36962.14260564996 29755.273052386034 37513.564632666465 0.9925306943782433 0.9764198989718302 0.9839489168093454 0.9889339342192943 0.9538628898270725 0.9721198312007078 1.223346906418189 0.9853007296849543 0.7931870336437028 1.0 15.195124737550904 IQFKPDDGIS(ph)PER ddPTM_PC-9_AZD4547_30min_R2 1 IQFKPDDGISPER 13 1 Q96I24 Q96I24 FUBP3 Far upstream element-binding protein 3 1 IQFKPDDGIS(1)PER 88.10799999999999 0.032659 3800500.0 9069.1 11938.0 11401.0 14282.0 14423.0 13132.0 10101.0 11862.0 12386.0 12293.0 True False 11952.885151001396 15796.72503968617 11249.815290718932 10989.505554700401 12420.615409102056 12310.853964054346 10999.969431770145 10029.000461642892 13040.698673479832 11862.62581169799 1.007608715029551 1.331638145755949 0.9483410729878412 0.9263973869818446 1.0470376126046075 1.0377849018818708 0.9272794747451985 0.8454283748673148 1.0993096200185393 1.0 13.534135767697858 -5.291349514042779 24.99702643287719 0.9742379511002244 1.1696234916648751 0.3673019310489646 0.09994925727338473 582.6142298157392 486911.64440276945 0.02501116786831782 0.05207482446958676 5.112702069109705e-06 5.291349514042779 0.19538554056465074 IQFKPDDGIS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 1 IQFKPDDGISPER 13 1 Q96I24 Q96I24 FUBP3 Far upstream element-binding protein 3 1 IQFKPDDGIS(1)PER 96.414 0.01977 0.0 17030.0 13357.0 15272.0 15990.0 16332.0 16423.0 13074.0 15438.0 13508.0 12026.0 True False 16787.149077080485 13326.07268715164 14016.395111624808 17165.957941076318 15371.38386994741 15720.626573882846 13750.9077484267 16155.305839189838 11986.586794453975 14104.67807636227 1.1901830716160555 0.9447980744406015 0.9937408734705251 1.217040037932123 1.0898074941326017 1.1145682651367073 0.9749182274121913 1.145386357045906 0.8498305831270294 1.0 13.783886117934061 -8.259644558105187 24.97837553143021 0.9249152908858167 1.0782066726831374 0.3216514874580456 0.09201061877111927 184.00433495797327 2560869.521778527 0.06887224859240564 0.022947227073210424 5.499908215586612e-09 8.259644558105187 0.1532913817973207 IQIISTDSAVAS(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 2 IQIISTDSAVASPQR 15 0 C9JKS0;P49116;P49116-2;C9JMI6;C9J2Y1 C9JKS0 NR2C2 Nuclear receptor subfamily 2 group C member 2 1 IQIISTDSAVAS(1)PQR;IQIISTDSAVAS(1)PQR 175.7 5.9196999999999996e-05 23594000.0 71915.0 71804.0 89538.0 110739.0 111965.0 99226.0 79715.0 94377.0 88013.0 81122.0 True False 94782.47407507554 95013.23879624942 88350.66761691016 85209.8344504948 96420.59240658043 93021.38253405863 86809.48057158261 79793.20321770967 92665.18749789937 78281.94347161523 1.2107833540111756 1.2137312205425879 1.1286212847915025 1.08849922053087 1.2317092311529314 1.1882865755343424 1.108933640655708 1.019305342701953 1.1837364197721976 1.0 16.25639195311836 -14.522878151184425 0.06830881245148777 0.45099699728423165 1.349970739603391 0.44187776115473243 0.058322694870704066 317.13717249241705 1.557885284887809 27.35313203908486 3.5605115115390764 3.0000041038719805e-15 14.522878151184425 0.8989737423191595 IQIISTDSAVAS(ph)PQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IQIISTDSAVASPQR 15 0 C9JKS0;P49116;P49116-2;C9JMI6;C9J2Y1 C9JKS0 NR2C2 Nuclear receptor subfamily 2 group C member 2 1 IQIISTDS(0.001)AVAS(0.998)PQR;IQIISTDSAVAS(1)PQR;IQIISTDSAVAS(1)PQR 171.15 0.0001325 24930300.0 87415.0 67354.0 76328.0 90730.0 95652.0 82701.0 96713.0 85541.0 84264.0 62988.0 True False 102212.6329750507 74040.45999292134 78147.94899555208 85646.69225062898 76909.67724362719 78364.01397321017 87551.64449851504 83295.6393881814 85496.20158817408 74407.2257872663 1.3736922979400057 0.9950708309513707 1.0502736551283431 1.1510534271966655 1.0336318338694082 1.05317747226938 1.1766551376183443 1.1194563230502301 1.1490308996684229 1.0 16.18315510977073 -4.749973006486634 24.99982275376648 1.0865405209880665 1.3736929282594668 0.6670916899828621 0.061931219807699944 325.68114248201596 710028.9664508988 0.01564374740232103 0.24287625529648582 1.7783899421843528e-05 4.749973006486634 0.28715240727140023 IQIISTDSAVAS(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 2 IQIISTDSAVASPQR 15 0 C9JKS0;P49116;P49116-2;C9JMI6;C9J2Y1 C9JKS0 NR2C2 Nuclear receptor subfamily 2 group C member 2 1 IQIIST(0.002)DSAVAS(0.997)PQR;IQIISTDSAVAS(1)PQR 149.31 2.6559e-05 23173000.0 95350.0 95788.0 85370.0 84591.0 82575.0 79965.0 78820.0 64206.0 81086.0 69769.0 True False 93990.29151495139 95566.20877119702 78351.20813772995 90812.10432730372 77718.10084869625 76545.08335751953 82900.913930778 67189.24515552689 71953.24080656617 81828.47868865108 1.1486256743520156 1.1678844615310102 0.9575053745756195 1.1097860522720262 0.9497683703054728 0.9354332939362795 1.0131058924632759 0.82109854945703 0.8793178360353102 1.0 16.320315409910684 -5.404775674356825 0.5344128978319439 0.9059263014815881 1.246593194707187 0.5740235017867508 0.07075867627284921 1.6295880342960316 0.5673862757961156 0.045850785584228365 0.3207685970218094 3.93753407945275e-06 5.404775674356825 0.34066689322559895 IQIVTAVDASGS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 IQIVTAVDASGSPK 14 0 C9JKS0;P49116;P49116-2;C9JMI6 C9JKS0 NR2C2 Nuclear receptor subfamily 2 group C member 2 1 IQIVTAVDAS(0.087)GS(0.913)PK;IQIVT(0.001)AVDAS(0.051)GS(0.949)PK 135.18 3.5605e-05 25544700.0 131969.0 123041.0 96254.0 113033.0 119655.0 114533.0 123117.0 113227.0 108080.0 119968.0 True False 173932.3968742766 162811.59705210457 94977.60906875365 86974.98819244157 103042.96864564293 107371.23340428251 134074.17449076756 95730.36884761766 113792.88815030688 115767.95683541718 1.5024226187350749 1.4063614967617293 0.8204136245038827 0.7512872349996687 0.8900819489466772 0.9274693649204506 1.1581285370819459 0.8269159399929102 0.9829394183062402 1.0 16.820876462549855 -5.210994958072486 5.9169122045131655 0.9152680401757214 1.4661950295363357 0.7938420996508693 0.10908332169306616 0.09263639817914537 7.683498732482031 0.029523850498995245 0.07950127888449429 6.151840146270105e-06 5.210994958072486 0.5509269893606143 IQIVTAVDASGS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IQIVTAVDASGSPK 14 0 C9JKS0;P49116;P49116-2;C9JMI6 C9JKS0 NR2C2 Nuclear receptor subfamily 2 group C member 2 1 IQIVTAVDAS(0.242)GS(0.758)PK 129.42 2.2639e-05 8739500.0 59133.0 62303.0 36279.0 60314.0 58592.0 41013.0 56608.0 49700.0 45278.0 41644.0 True False 69143.04897001277 68488.03009381743 37144.02894887367 56934.80212062628 47111.318206191296 38862.20608073985 51245.68043357094 48395.4276615028 45940.105092439684 49193.727546277405 1.4055257127032847 1.3922106233846487 0.7550561992671042 1.1573589756349874 0.957669210203127 0.7899829514683857 1.0417116772735553 0.9837723237373376 0.9338610303360936 1.0 15.586186755789422 -5.2435452889223635 24.835554956574523 0.9567404426865532 1.3988683076077255 0.7278749756795643 0.10916391553001063 368.29119451263824 511156.3910135392 0.026846136393739107 0.07069301325458383 5.707615531417829e-06 5.2435452889223635 0.4421278649211723 IQIVTAVDASGS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 IQIVTAVDASGSPK 14 0 C9JKS0;P49116;P49116-2;C9JMI6 C9JKS0 NR2C2 Nuclear receptor subfamily 2 group C member 2 1 IQIVTAVDAS(0.044)GS(0.956)PK 145.82 0.00018898 7830100.0 68248.0 71870.0 53875.0 52193.0 57011.0 56129.0 57199.0 53886.0 53036.0 48368.0 True False 67274.77100484974 71703.58943067951 49445.605463514075 56031.44733074396 53657.725067938525 53728.49351308964 60160.4843431435 56389.74028051456 47062.52718616085 56728.34435369118 1.1859110603581775 1.2639817052234124 0.8716208101408616 0.9877151883967883 0.945871515893221 0.947119012994668 1.0605013248413093 0.9940311306978133 0.8296122110092677 1.0 15.7917821383657 -5.25509292408179 24.993630941577223 0.95873756148743 1.2249464094671405 0.7367137151867447 0.064617747177978 244.1113689795949 961353.5607091556 0.0164014134640319 0.041182296463668756 5.5578532560348796e-06 5.25509292408179 0.26620884797971056 IQNTGDY(ph)YDLYGGEK ddPTM_PC-9_AZD4547_30min_R2 2 IQNTGDYYDLYGGEK 15 0 Q06124;Q06124-1;A0A1W2PPU4;Q06124-3 Q06124 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 1 IQNT(0.001)GDY(0.792)Y(0.184)DLY(0.024)GGEK;IQNT(0.051)GDY(0.679)Y(0.266)DLY(0.003)GGEK 162.88 0.00021584 13538900.0 38580.0 36583.0 60634.0 69703.0 67460.0 53097.0 49957.0 52430.0 56317.0 52183.0 True False 50847.637486148975 48407.73933044387 59829.953542448166 53634.05025061491 58094.343444361446 49776.83619626817 54403.07622046739 44328.1482215425 59293.80164656584 50356.089053269025 1.0097614497496017 0.9613085575259012 1.1881374162945268 1.0650956271420982 1.153670678890621 0.9884968656642874 1.080367384427279 0.8802937053878451 1.1774902054812493 1.0 15.619878618870173 -6.805959013252327 24.999888519424758 1.0212878744194085 1.0749152581961314 0.06789168712353111 0.09250242498249227 385.989247698984 216748.5262906665 0.031835761770719735 0.02807664143845728 1.5632951724024628e-07 6.805959013252327 0.05362738377672294 IQNTGDY(ph)YDLYGGEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IQNTGDYYDLYGGEK 15 0 Q06124;Q06124-1;A0A1W2PPU4;Q06124-3 Q06124 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 1 IQNT(0.003)GDY(0.771)Y(0.226)DLYGGEK 176.43 7.7474e-05 4209000.0 13271.0 13856.0 12848.0 21986.0 23184.0 12134.0 19572.0 13291.0 14797.0 10366.0 True False 15517.518185802197 15231.53210888614 13154.345046311331 20754.195699573727 18641.26162773654 11497.671679313804 17717.998470990875 12942.125332978547 15013.378131826266 12245.273742789146 1.267225095309933 1.2438702824308445 1.074238544814689 1.6948739681540574 1.5223229810369727 0.9389477051163857 1.446925470443194 1.0569078000889736 1.226054921039815 1.0 13.579937405223497 -8.205916101131194 0.7490343413446371 1.0166319098573482 1.3223123470911544 0.16639391540186887 0.21199147393594442 1.1943769459469245 1.4562178202549079 0.20823142824122587 0.08500857483669604 6.224205154174989e-09 8.205916101131194 0.3056804372338062 IQNTGDY(ph)YDLYGGEK ddPTM_PC-9_Lapatinib_30min_R1 3 IQNTGDYYDLYGGEK 15 0 Q06124;Q06124-1;A0A1W2PPU4;Q06124-3 Q06124 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 1 IQNT(0.001)GDY(0.915)Y(0.084)DLYGGEK;IQNT(0.015)GDY(0.492)Y(0.492)DLY(0.001)GGEK;IQNTGDY(0.782)Y(0.216)DLY(0.001)GGEK 134.68 2.7889e-05 9230600.0 86097.5 91156.0 91345.8 82896.4 89263.9 87226.0 75859.0 80213.8 99233.5 79170.5 True False 84869.73386165207 90944.93388260812 83835.70092898498 88992.87779028364 84013.57290157958 83495.54731373723 79786.60783906233 83940.82598287372 88056.77825491916 92855.01543694001 0.9140026897016572 0.9794294196673838 0.9028666952935864 0.9584067954920622 0.9047822835012627 0.8992034185858382 0.8592600783449038 0.903998837196682 0.9483254926032569 1.0 16.502692217018527 -3.8708110055042697 15.78466119239417 0.9227435317801634 0.9284292883362947 0.0 0.04103401469329704 0.0 0.0 0.009326076126298481 0.0 0.00013464461675149816 3.8708110055042697 0.005685756556131238 IQNTGDYY(ph)DLYGGEK ddPTM_PC-9_Lapatinib_30min_R1 1 IQNTGDYYDLYGGEK 15 0 Q06124;Q06124-1;A0A1W2PPU4;Q06124-3 Q06124 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 1 IQNT(0.001)GDY(0.336)Y(0.636)DLY(0.026)GGEK 150.12 6.706e-10 0.0 20897.0 22834.0 22931.0 25795.0 23977.0 24644.0 20085.0 17440.0 21617.0 18375.0 True False 20599.004947959533 22781.129275916788 21045.70169621977 27692.050349597466 22566.720000595706 23590.03356796985 21124.90302334023 18250.326067850157 19182.265822898407 21551.09426685155 0.9558217644494992 1.0570752925041582 0.9765490993462388 1.2849486901549831 1.0471264113630798 1.094609548632269 0.9802241483316763 0.8468398793058777 0.8900831477686627 1.0 14.395473504236445 -7.485147534169431 3.9754429292535503 0.9016476406414986 1.0725306165074917 0.37665218158866387 0.0908060110165264 0.22271265180776176 7.572511866704263 0.042923547607614125 0.02627988311602791 3.2722951286406604e-08 7.485147534169431 0.1708829758659931 IQNWHEEHR ddPTM_PC-9_AZD4547_30min_R2 4 IQNWHEEHR 9 0 A0A2R8Y7M3;A0A2R8Y5S7;P35241;P35241-5;P35241-4 A0A2R8Y7M3 RDX Radixin 0 ;;; 90.709 0.0035183 34102100.0 23005.38 20486.469999999998 28685.6 45726.0 37315.6 30775.37 25289.43 29957.800000000003 25709.54 33880.799999999996 False True 30320.6122983697 27108.32079274414 28305.21020116193 35184.577159657645 32134.97305414191 28850.98124883786 27540.140277882474 25328.51037175904 27068.493797333827 32694.6435045129 0.9273877628971391 0.8291364543859403 0.8657445736410894 1.076157235199737 0.9828818916378844 0.8824375541778122 0.8423441067366604 0.7746990839114946 0.8279183039141416 1.0 14.99676667207774 -6.9850777399913335 5.576949929497221 0.844701730963738 0.9344028857286856 0.1479413663630248 0.08223467612430246 0.294757068074719 29.84353315488025 0.03185695177122507 0.027066508426052883 1.0349568897658856e-07 6.9850777399913335 0.08970115476494755 IQNWHEEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IQNWHEEHR 9 0 A0A2R8Y7M3;A0A2R8Y5S7;P35241;P35241-5;P35241-4 A0A2R8Y7M3 RDX Radixin 0 ;;; 94.309 0.0024349 25966300.0 15644.9 15537.5 19489.600000000002 17230.4 26594.5 19554.5 20759.899999999998 20207.3 16578.8 13753.199999999999 False True 18293.27256913998 17079.960316239783 19954.30597871961 16265.036549710503 21383.498635215623 18529.027596270145 18793.37198333962 19676.879786404144 16821.233585991857 16246.546289728703 1.1259791615344885 1.0512979196715782 1.2282183316299664 1.0011381040408256 1.3161873455366064 1.1404902473324106 1.1567610523610827 1.2111423212971821 1.0353728900908914 1.0 13.987845440444236 -8.409343520323008 5.194800237247883 1.0016497572991734 1.152593486971252 0.30071577503354596 0.08374065179803247 0.2551975029325435 9.172340506935852 0.07680976942740982 0.01998712099713699 3.896336704547825e-09 8.409343520323008 0.15094372967207859 IQNWHEEHR ddPTM_PC-9_Lapatinib_30min_R1 2 IQNWHEEHR 9 0 A0A2R8Y7M3;A0A2R8Y5S7;P35241;P35241-5;P35241-4 A0A2R8Y7M3 RDX Radixin 0 ; 91.265 0.0033375 18063700.0 11599.9 11095.9 8307.3 9702.599999999999 9191.0 10194.8 6720.799999999999 6793.0 12115.2 5851.4 False True 11434.483298838863 11070.208125280065 7624.305861105341 10416.161570924769 8650.40345020125 9758.792169239532 7068.770138873039 7108.627579065716 10750.658597288191 6862.806693499593 1.6661526121185275 1.6130729918075204 1.1109603113733386 1.517769920693073 1.2604760466872622 1.4219826675991032 1.0300115469620517 1.0358192932636385 1.5665104785001662 1.0 12.744583003141173 -1.5228787452803376 0.3423270289335051 1.1681041504392526 6.939305546606194 0.3736114791240833 0.19872023575073613 65.4371798372418 0.9259718152077745 0.17009894726634803 241.93183716347005 0.029999999999999995 1.5228787452803376 5.7712013961669415 IQPAGNTS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 IQPAGNTSPR 10 0 H0Y5S9;H0Y682;P49674 H0Y5S9 CSNK1E Casein kinase I isoform epsilon 1 IQPAGNT(0.229)S(0.771)PR 86.189 0.011425 95934000.0 135130.0 145330.0 190140.0 266290.0 218350.0 183820.0 182500.0 239230.0 189560.0 180930.0 True False 178098.5291213922 192305.08041695348 187618.61936473107 204900.9546394881 188035.87149535044 172325.70634118732 198742.14645065382 202262.50045850917 199579.75460558987 174595.69577080553 1.020062541262099 1.1014308203187055 1.0745890300240903 1.1735739173574173 1.0769788491360521 0.9869985945552858 1.1382992322533867 1.1584621233963424 1.1430966480845055 1.0 17.413658467730308 IQPAGNTS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IQPAGNTSPR 10 0 H0Y5S9;H0Y682;P49674 H0Y5S9 CSNK1E Casein kinase I isoform epsilon 1 IQPAGNT(0.236)S(0.764)PR;IQPAGNT(0.053)S(0.947)PR;IQPAGNT(0.084)S(0.916)PR;IQPAGNT(0.232)S(0.768)PR 98.898 0.0045817 139738000.0 422729.0 454831.0 560401.0 573220.0 635951.0 529655.0 559053.0 485643.0 507915.0 416065.0 True False 494288.67042167054 499983.6158066386 573763.085172627 541104.3418043153 511340.9667624521 501878.9593956616 506095.4526467851 472895.38583129173 515342.2959942234 491494.29093127104 1.0056854770074841 1.017272479115235 1.1673850454813526 1.100937186430069 1.0403802774465112 1.021128767222736 1.0297076934257938 0.9621584513937312 1.0485214284336157 1.0 18.906815133132923 -6.591050215267669 2.930926231717438 1.0104527321248846 1.0753080818563567 0.26831990304756625 0.04671345432364465 0.37255893292798076 6.496412863995292 0.0175910902154088 0.017977191156616345 2.564187535380572e-07 6.591050215267669 0.06485534973147211 IQPAGNTS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 IQPAGNTSPR 10 0 H0Y5S9;H0Y682;P49674 H0Y5S9 CSNK1E Casein kinase I isoform epsilon 1 IQPAGNT(0.233)S(0.767)PR;IQPAGNT(0.077)S(0.923)PR;IQPAGNT(0.035)S(0.965)PR 91.70100000000001 0.007903199999999999 123817700.0 447662.0 371965.0 427387.0 356702.0 354843.0 356387.0 323451.0 340844.0 387403.0 254709.0 True False 441278.2577888434 371103.73789596074 392248.8906215295 382935.055002989 333971.8323881794 341145.15878867405 340197.7101221021 356680.85655219696 343769.59460555646 298735.11127159133 1.477155651073304 1.242250153710845 1.3130324351626725 1.2818548625670196 1.1179530620508582 1.1419653931423084 1.1387938587935704 1.193970320508877 1.1507505533657294 1.0 18.188507286509605 -1.5228787452803376 0.2414683403917462 1.0690838265119706 3.203132190146609 0.7642621286218777 0.060262553725259856 26.082808432979604 0.3494381718357494 0.08343086466529691 22.349863934975158 0.029999999999999995 1.5228787452803376 2.134048363634639 IQPEEKPVEVS(ph)PAVTK ddPTM_PC-9_AZD4547_30min_R2 2 IQPEEKPVEVSPAVTK 16 1 Q8N0X7 Q8N0X7 SPG20 Spartin 1 IQPEEKPVEVS(0.99)PAVT(0.01)K;IQPEEKPVEVS(0.999)PAVT(0.001)K 94.911 0.0011960999999999999 33317000.0 62120.0 67296.0 76654.0 88255.0 89545.0 81719.0 73609.0 95531.0 77199.0 76704.0 True False 81872.86782373197 89048.1159549942 75637.51787516617 67909.17327615763 77113.22240921049 76609.09801161714 80160.05840047216 80768.87903399151 81279.58153511795 74018.61630688046 1.1061118392741613 1.2030502648928423 1.0218715459577596 0.917460723591574 1.0418084835509465 1.034997705090792 1.082971587419702 1.0911968240411916 1.0980964734349208 1.0 16.175600545910896 -5.271637673597856 24.87823205697433 1.0369159019877259 1.154581053290208 0.4332718923020139 0.05421753691477353 584.2778211168078 1425317.2904871965 0.015431497780130553 0.03270547621609324 5.350105257813497e-06 5.271637673597856 0.11766515130248223 IQPEEKPVEVS(ph)PAVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IQPEEKPVEVSPAVTK 16 1 Q8N0X7 Q8N0X7 SPG20 Spartin 1 IQPEEKPVEVS(0.862)PAVT(0.138)K;IQPEEKPVEVS(0.989)PAVT(0.011)K;IQPEEKPVEVS(0.994)PAVT(0.006)K 73.722 0.006622800000000001 20804600.0 76222.0 80088.0 84743.0 89747.0 86744.0 65320.0 81399.0 64751.0 58017.0 51535.0 True False 89124.87914687792 88038.60735684718 86763.59450961734 84718.76655369991 69747.13589701432 61894.504210711864 73688.29744227378 63051.35485935552 58865.38886761943 60877.887549164465 1.4639942799411598 1.4461508258766034 1.4252070497608478 1.3916180400524205 1.145689160792367 1.0166992762474945 1.2104279634007296 1.0357020816209461 0.9669420414773795 1.0 15.893630678022644 -6.294975712308241 2.389370616498521 1.0571134635293284 1.4451162214478028 0.8979461468081744 0.06183296611699664 0.09359125623441969 1.0513273356380084 0.02144790363920602 0.026683377799557054 5.070190622577358e-07 6.294975712308241 0.3880027579184744 IQPEEKPVEVS(ph)PAVTK ddPTM_PC-9_Lapatinib_30min_R1 2 IQPEEKPVEVSPAVTK 16 1 Q8N0X7 Q8N0X7 SPG20 Spartin 1 IQPEEKPVEVS(0.999)PAVT(0.001)K;IQPEEKPVEVS(0.98)PAVT(0.02)K 101.17 0.00079063 23018000.0 129843.0 134932.0 143732.0 123742.0 99970.0 102177.0 106046.0 85554.0 110422.0 83277.0 True False 127991.41500971008 134619.57324419764 131914.9097815647 132842.39947121128 94089.96114858214 97807.12789622051 111536.54299293701 89529.15117023214 97985.11156479092 97671.31849037236 1.3104298886097911 1.378291757753504 1.3506002767288106 1.3600963059007523 0.9633325586554538 1.001390473763918 1.1419579945972713 0.9166370696537407 1.0032127453511288 1.0 16.57564735170623 -6.2578502095603366 24.985447192734643 1.006978897982245 1.3519390693413609 0.9026883157374692 0.05555712662035578 90.04042598888118 626801.9997331962 0.016890038555755098 0.020950115933298548 5.522678865200674e-07 6.2578502095603366 0.34496017135911594 IQPQPPDEDGDHS(ph)DKEDEQPQVVVLK ddPTM_PC-9_AZD4547_30min_R2 2 IQPQPPDEDGDHSDKEDEQPQVVVLK 26 1 Q96AT1 Q96AT1 KIAA1143 Uncharacterized protein KIAA1143 1 IQPQPPDEDGDHS(1)DKEDEQPQVVVLK;IQPQPPDEDGDHS(1)DKEDEQPQVVVLK 43.888000000000005 0.021294 27172000.0 160555.0 141386.0 138206.0 148059.0 152413.0 150814.0 143183.0 151641.0 148092.0 146016.0 True False 211608.1502485395 187086.25954607717 136373.29813780385 113926.28503874714 131253.08578988258 141383.5767388739 155926.00961777527 128208.36781352128 155919.84078418987 140904.02428381113 1.5017892592074942 1.3277566804567984 0.9678453034323461 0.8085381919914154 0.9315070059710326 1.003403397862483 1.1066114712501511 0.9098985530411959 1.1065676908569597 1.0 17.104353290707415 -5.133129789363472 3.1467370073832823 0.9727662331972051 1.477311196880944 0.8131380708329053 0.08518934443913179 0.10701579958298803 1.9385081546458074 0.02379697660014341 0.08484794058904593 7.359871141007838e-06 5.133129789363472 0.5045449636837389 IQPQPPDEDGDHS(ph)DKEDEQPQVVVLK ddPTM_PC-9_Lapatinib_30min_R1 6 IQPQPPDEDGDHSDKEDEQPQVVVLK 26 1 Q96AT1 Q96AT1 KIAA1143 Uncharacterized protein KIAA1143 1 IQPQPPDEDGDHS(1)DKEDEQPQVVVLK;IQPQPPDEDGDHS(1)DKEDEQPQVVVLK;IQPQPPDEDGDHS(1)DKEDEQPQVVVLK;IQPQPPDEDGDHS(1)DKEDEQPQVVVLK;IQPQPPDEDGDHS(1)DKEDEQPQVVVLK;IQPQPPDEDGDHS(1)DKEDEQPQVVVLK 96.34100000000001 1.9639000000000002e-09 73130300.0 223431.0 225409.8 200942.0 218084.0 231148.0 215152.0 203279.0 221365.0 208849.0 195687.0 True False 220244.83296777226 224887.87745723635 184421.32441855114 234122.6248668978 217552.32909445316 205950.45050380848 213803.79196821398 231650.42603266315 185326.22634253182 229511.2372134632 0.9596254878053205 0.9798556279319484 0.8035394112185672 1.0200922085969395 0.9478940192026967 0.897343646456224 0.9315613238116089 1.009320627805297 0.8074821459402621 1.0 17.808205266312285 IQPS(ph)SPPPNHPNNHLFR ddPTM_PC-9_AZD4547_30min_R2 1 IQPSSPPPNHPNNHLFR 17 0 H0Y4E8;Q9Y2K2-7;Q9Y2K2;Q9Y2K2-8 H0Y4E8 SIK3 Serine/threonine-protein kinase SIK3 1 IQPS(0.5)S(0.5)PPPNHPNNHLFR 58.81399999999999 0.023204 12683000.0 6718.2 4047.7 15788.0 25155.0 17827.0 17263.0 14555.0 20681.0 15849.0 20699.0 True False 8854.447852759098 5356.039867912358 15578.640804304061 19355.903390875817 15352.02876641909 16183.541881013565 15850.366803228846 17485.226652102247 16686.745783625214 19974.334310285263 0.443291261436419 0.26814610112710513 0.779932916026255 0.9690387219016856 0.7685877550629541 0.8102168327422192 0.7935366734633611 0.8753847002099432 0.8354093570484004 1.0 14.285859802439694 -5.330613023291962 5.218471758829022 0.8507020513999716 0.35645695980944225 0.8573136507882273 0.08157059539520733 0.06279500027102937 3.256563304395615 0.020390151411868687 0.044455943227065586 4.670753809719677e-06 5.330613023291962 -0.4942450915905293 IQPS(ph)SPPPNHPNNHLFR ddPTM_PC-9_Lapatinib_30min_R1 2 IQPSSPPPNHPNNHLFR 17 0 H0Y4E8;Q9Y2K2-7;Q9Y2K2;Q9Y2K2-8 H0Y4E8 SIK3 Serine/threonine-protein kinase SIK3 1 IQPS(0.5)S(0.5)PPPNHPNNHLFR;IQPS(0.733)S(0.267)PPPNHPNNHLFR 57.788000000000004 0.025149 22912000.0 39562.0 36308.0 45576.0 28859.0 48255.0 48809.0 48116.0 44389.0 60564.0 45786.0 True False 38997.83862521774 36223.93105675688 41828.91720844764 30981.387130801824 45416.7357729802 46721.55284933617 50607.21104660386 46451.47499001149 53742.644552806494 53700.04909398992 0.7262160702490373 0.67456048305198 0.7789362936193127 0.5769340559926833 0.8457484963093492 0.8700467436735588 0.942405303168853 0.865017365416344 1.0007932107984114 1.0 15.712635786710294 -6.559578790850193 2.719187407478373 0.9301281998113528 0.6946065611866786 0.7572760355840148 0.06523524302945176 0.13301849659333143 1.9978776443165094 0.0217308877285948 0.022684077246100748 2.756901242679334e-07 6.559578790850193 -0.23552163862467412 IQQALTS(ph)PLPMTPILEGSHR ddPTM_PC-9_Lapatinib_30min_R1 1 IQQALTSPLPMTPILEGSHR 20 0 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 IQQALT(0.223)S(0.768)PLPMT(0.008)PILEGSHR 63.488 0.005631000000000001 3645300.0 14220.0 10448.0 10235.0 4882.0 8419.8 12735.0 10076.0 12635.0 11651.0 13237.0 True False 14017.220192371378 10423.808297923213 9393.517808242526 5241.038565874581 7924.5639179637055 12190.353736734947 10597.685977753361 13222.06822633525 10338.741689530885 15524.99781280619 0.9028806548886543 0.6714209189340349 0.6050575930190498 0.3375870727370652 0.5104389716194953 0.7852080807817843 0.6826207710645594 0.851663129731889 0.6659415875088054 1.0 13.922305444745358 -8.56224501128602 0.6063914621815852 0.9903558608284736 0.6152002723007912 0.3152071902537791 0.1525820588845387 1.156624179649991 0.9852705791737073 0.17316425646845518 0.0734414890144606 2.74002792347299e-09 8.56224501128602 -0.3751555885276824 IQQALTSPLPMT(ph)PILEGSHR ddPTM_PC-9_AZD4547_30min_R2 2 IQQALTSPLPMTPILEGSHR 20 0 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 IQQALT(0.012)S(0.023)PLPMT(0.961)PILEGS(0.004)HR;IQQALT(0.016)S(0.04)PLPMT(0.927)PILEGS(0.017)HR 70.704 0.0040691 12780500.0 30858.0 31679.0 35726.0 54453.0 45667.0 46864.0 39202.0 55878.0 49352.0 52960.0 True False 40670.20211372697 41918.617233390716 35252.249897046284 41899.70214046358 39326.925319799186 43933.58667159933 42690.902055663115 47243.339048700225 51960.64596589514 51105.886519769396 0.7958026928658097 0.8202307031143125 0.6897884431260102 0.8198605873758874 0.7695185035991161 0.8596580484834053 0.8353421682480531 0.9244206933075114 1.01672526404165 1.0 15.641201853956344 -7.7666827564266265 1.0286631053570574 1.0187110628131955 0.779954931977501 0.822362746151242 0.04062820603284097 0.20761712915248776 0.39758246787079315 0.0350779402841286 0.01413108994827612 1.7112649039742958e-08 7.7666827564266265 -0.23875613083569447 IQQFDDGGS(ph)DEEDIWEEK ddPTM_PC-9_AZD4547_30min_R2 1 IQQFDDGGSDEEDIWEEK 18 0 H0YEN2;E9PQP7;H7BXH2;E9PKF6;Q5H9R7-4;Q5H9R7-6;Q5H9R7-2;Q5H9R7;Q5H9R7-5;Q5H9R7-3 H0YEN2 PPP6R3 Serine/threonine-protein phosphatase 6 regulatory subunit 3 1 IQQFDDGGS(1)DEEDIWEEK 106.63 0.0012577 0.0 10542.0 10376.0 10070.0 9202.9 10516.0 12700.0 10792.0 10966.0 11621.0 10147.0 True False 13894.13671277819 13729.83908626099 9936.465220378888 7081.313588387643 9056.034919373033 11905.866992346188 11752.46709312578 9271.456673611194 12235.262335258298 9791.756618506424 1.4189626288829795 1.402183450956245 1.0147786150647335 0.7231913398464129 0.924863155019307 1.215907161115922 1.2002409323485035 0.946863472493601 1.2495472275254111 1.0 13.25735198386529 -5.259034080690186 22.31868114926097 1.029901467138003 1.4105732610177677 0.5012146126921199 0.15004030875561086 39.51411048871701 366617.58511130675 0.04196137788299129 0.10043150925503887 5.507644741893628e-06 5.259034080690186 0.3806717938797648 IQQFDDGGS(ph)DEEDIWEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 IQQFDDGGSDEEDIWEEK 18 0 H0YEN2;E9PQP7;H7BXH2;E9PKF6;Q5H9R7-4;Q5H9R7-6;Q5H9R7-2;Q5H9R7;Q5H9R7-5;Q5H9R7-3 H0YEN2 PPP6R3 Serine/threonine-protein phosphatase 6 regulatory subunit 3 1 IQQFDDGGS(1)DEEDIWEEK;IQQFDDGGS(1)DEEDIWEEK;IQQFDDGGS(1)DEEDIWEEK 101.5 0.0018482 1669800.0 34391.7 31481.1 31561.3 37713.0 37921.2 36715.0 34557.1 34947.7 33131.2 27760.0 True False 40213.53554296233 34606.33555665816 32313.841088896806 35600.06287719569 30490.8130796119 34789.6007669364 31283.60131626192 34030.35990514895 33615.68112192758 32792.66825196093 1.2262965378109372 1.055307097634203 0.985398346990703 1.085610435956729 0.9298057982149291 1.0608957008204434 0.9539815752684665 1.0377429382591947 1.0250974658006804 1.0 15.001085674304422 -4.769572471456322 3.0085793266581424 1.0108921379182858 1.26504627292846 0.6811761584662743 0.044334219779740315 0.21160819480834628 2.7141825230604515 0.010412413761306232 0.13313695754041838 1.6999162620649688e-05 4.769572471456322 0.25415413501017414 IQQFDDGGS(ph)DEEDIWEEK ddPTM_PC-9_Lapatinib_30min_R1 2 IQQFDDGGSDEEDIWEEK 18 0 H0YEN2;E9PQP7;H7BXH2;E9PKF6;Q5H9R7-4;Q5H9R7-6;Q5H9R7-2;Q5H9R7;Q5H9R7-5;Q5H9R7-3 H0YEN2 PPP6R3 Serine/threonine-protein phosphatase 6 regulatory subunit 3 1 IQQFDDGGS(1)DEEDIWEEK;IQQFDDGGS(1)DEEDIWEEK 122.73 0.00011239 0.0 14498.699999999999 14842.0 15330.6 14768.0 17897.0 13823.5 12136.3 13275.8 16183.1 13457.599999999999 True False 14291.945879264062 14807.634260889767 14070.177245827346 15854.087984603817 16844.33364685581 13232.301129152389 12764.658230628032 13892.642133690659 14360.388862402137 15783.728228875165 0.9054860595684866 0.9381582124431346 0.8914356001193049 1.0044577399400436 1.0671961277209743 0.8383507962931642 0.8087226316578382 0.8801876167808754 0.9098223597217586 1.0 13.94615039998423 -6.806516391658114 24.999999640796503 0.8750100151546664 0.9585703781676137 0.22513896149950974 0.06651773644422031 185.04883166328398 102627.96704212531 0.024238767621455878 0.0213766756607627 1.5612901087920595e-07 6.806516391658114 0.08356036301294734 IQQNQS(ph)IR ddPTM_PC-9_AZD4547_30min_R2 2 IQQNQSIR 8 0 E9PF63;O75116;Q14DU5 E9PF63 ROCK2 Rho-associated protein kinase 2 1 IQQNQS(1)IR;IQQNQS(1)IR 102.06 0.010971 0.0 43295.0 40396.0 64439.0 67904.0 72289.0 61935.0 56556.0 94446.0 58855.0 71666.0 True False 57061.90940805652 53453.21701316492 63584.496756305394 52249.78190634198 62252.920148968995 58062.194659130815 61589.37443651054 79851.54085317181 61965.955145136075 69156.9951534327 0.8251068352732526 0.7729256728776727 0.9194224910326991 0.7555241778567716 0.9001680887212317 0.8395708131955878 0.890573315105254 1.1546415612189633 0.8960186168826092 1.0 16.07758756531075 -7.539782772127867 23.178364438289808 1.019719793958772 0.8381807696047742 0.5419827550307574 0.07456579617079914 72.78845672869565 99802.79366699884 0.032468277713912065 0.018754388421795817 2.8854744151597785e-08 7.539782772127867 -0.18153902435399794 IQQNQS(ph)IR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IQQNQSIR 8 0 E9PF63;O75116;Q14DU5 E9PF63 ROCK2 Rho-associated protein kinase 2 1 IQQNQS(1)IR 112.85 0.0037234 15371000.0 14194.0 22421.0 31095.0 22002.0 31764.0 36159.0 17858.0 24398.0 22002.0 19104.0 True False 16596.763855721216 24646.808704773102 31836.422728444177 20769.29927144644 25540.0722197819 34262.758385718465 16166.360959276259 23757.57835181783 22323.73762630545 22567.40397281922 0.7354307954832022 1.0921419554707477 1.4107259641733187 0.9203229266627894 1.1317239789983395 1.5182410181953336 0.7163589121171161 1.0527386482039356 0.989202730327013 1.0 14.461952848103603 -7.3005974352052965 24.99998218096325 0.9439700931180044 1.135485751534639 0.1546661361527375 0.2234532725070902 1129.5649186378773 721152.5820561132 0.09412354440439365 0.06345928421459442 5.0049825172197016e-08 7.3005974352052965 0.19151565841663465 IQQNQS(ph)IR ddPTM_PC-9_Lapatinib_30min_R1 1 IQQNQSIR 8 0 E9PF63;O75116;Q14DU5 E9PF63 ROCK2 Rho-associated protein kinase 2 1 IQQNQS(1)IR 96.665 0.0164 0.0 29354.0 10345.0 40943.0 31625.0 34642.0 11681.0 28954.0 7252.1 25526.0 25748.0 True False 28935.406577135695 10321.046788094907 37576.824584550464 33950.80799790736 32604.425668792468 11181.43085974095 30453.096446989963 7589.059041092669 22650.993079303527 30198.507492946563 0.9581733992613414 0.34177340686474605 1.2443272103208163 1.124254501843749 1.0796701021203732 0.3702643537053143 1.0084305144584667 0.25130576545431055 0.7500699524502692 1.0 14.882189628247703 -6.742973958923767 24.992814673090585 0.649996643446597 0.9419417115404934 0.15474437763499072 0.316592207224029 453.3892343623839 613657.7834720133 0.10440000756045503 0.10421578205783942 1.8072824906623203e-07 6.742973958923767 0.2919450680938964 IQQNTFTR ddPTM_PC-9_Lapatinib_30min_R1 1 IQQNTFTR 8 0 Q60FE5;P21333-2;P21333;A0A087WWY3;F8WE98;O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;O75369-5;O75369-4;Q14315-2;Q14315 Q60FE5;O75369-2;Q14315-2 FLNA;FLNB;FLNC Filamin-A;Filamin-B;Filamin-C 0 127.46 0.016649 10743000.0 35726.0 44547.0 41986.0 41861.0 56357.0 54859.0 50092.0 36467.0 34659.0 42017.0 False True 35216.54068865399 44443.8541584595 38534.07315064687 44939.59758420237 53042.192062125054 52512.80845257501 52685.51865796159 38161.38994932863 30755.338444549932 49279.58246586671 0.7146274161930365 0.9018715649476807 0.7819480446559653 0.911931378788154 1.0763523026775743 1.0656098494533264 1.0691145505231094 0.7743854156183436 0.6240990062335143 1.0 15.58870241202351 -4.31066451714123 0.9463413705494361 0.9302971638074131 0.41610119214397934 0.1508628752415918 0.14181044142841837 9.692982441765915 3.7292639681232873 0.052028243820591215 6.320375364704946 4.890299782891414e-05 4.31066451714123 -0.5141959716634338 IQRPNTTQEGEEMETDMDVADVAMES(ph)SPGSSISMEHR ddPTM_PC-9_AZD4547_30min_R2 1 IQRPNTTQEGEEMETDMDVADVAMESSPGSSISMEHR 37 1 A0A087X1S3 A0A087X1S3 HUWE1 1 IQRPNTTQEGEEMET(0.033)DMDVADVAMES(0.45)S(0.45)PGS(0.035)S(0.025)IS(0.007)MEHR 49.281000000000006 0.030166000000000002 5384100.0 1826.9 2852.7 6299.3 6855.8 9997.6 4954.1 4733.1 5765.2 5109.9 5914.8 True False 2407.816198119377 3774.7794874110205 6215.7671661105005 5275.301231054124 8609.605811137684 4644.31934384112 5154.336730770352 4874.320811116476 5379.998881932395 5707.724652325002 0.42185219939412627 0.6613457581338283 1.0890096395204611 0.9242389134705835 1.5084129553500134 0.8136901526862002 0.9030457922791998 0.8539866773585434 0.9425820637197153 1.0 12.47870002376679 -5.047805275565973 3.1045137629591504 1.0035885077930315 0.4369160671949882 0.5154491558946549 0.1857486590559595 0.2137267391245884 3.909246220041118 0.05027799997924217 0.21425192213648378 8.957663098860091e-06 5.047805275565973 -0.5666724405980433 IQRPNTTQEGEEMETDMDVADVAMESS(ph)PGSSISMEHR ddPTM_PC-9_AZD4547_30min_R2 1 IQRPNTTQEGEEMETDMDVADVAMESSPGSSISMEHR 37 1 A0A087X1S3 A0A087X1S3 HUWE1 1 IQRPNTTQEGEEMET(0.001)DMDVADVAMES(0.301)S(0.669)PGS(0.017)S(0.008)IS(0.005)MEHR 59.406000000000006 0.0011269 8374400.0 6209.8 5442.2 13989.0 21571.0 14353.0 16041.0 10836.0 16873.0 15908.0 14524.0 True False 8184.387228136027 7201.284721978561 13803.496719749766 16598.139218627803 12360.333700814112 15037.953734190953 11800.383007886474 14265.665552967512 16748.864403174324 14015.519180761541 0.5839517696476317 0.5138079174308029 0.9848723077413495 1.1842685957300323 0.8819033773490584 1.0729501733216462 0.8419511868018644 1.0178478134830236 1.1950227592114262 1.0 13.774737567061972 -5.282551489450862 6.772586982899506 1.0200397326172912 0.5476957688434747 0.7572074148905996 0.10726900456878401 0.07114059804039163 14.951297510480844 0.027759824662428274 0.06155855874001083 5.217332444827649e-06 5.282551489450862 -0.4723439637738165 IQRPNTTQEGEEMETDMDVADVAMESSPGSS(ph)ISMEHR ddPTM_PC-9_Lapatinib_30min_R1 1 IQRPNTTQEGEEMETDMDVADVAMESSPGSSISMEHR 37 1 A0A087X1S3 A0A087X1S3 HUWE1 1 IQRPNTTQEGEEMET(0.003)DMDVADVAMES(0.169)S(0.169)PGS(0.061)S(0.421)IS(0.178)MEHR 46.184 0.0015072 4357000.0 2518.9 3002.2 9388.0 6606.4 5871.0 7251.4 8082.7 4434.2 7082.9 2358.4 True False 2482.9800240903146 2995.248590354618 8616.154878727984 7092.256694304353 5525.679322830105 6941.27452583901 8501.182657045163 4640.2291198429575 6285.149215756446 2766.0462976295316 0.8976639422912764 1.0828627824926538 3.1149713170426416 2.56404120942673 1.9976814298320116 2.5094571019247214 3.073405772105324 1.677567408694344 2.272250186536192 1.0 11.4336095889457 -5.1551757417691055 7.101078624150275 2.335926608122382 0.954208137014885 0.42313589586134703 0.5982273522909558 0.2171898370304891 12.663967994811793 0.14646216086678815 0.3950188258595682 6.995588549676425e-06 5.1551757417691055 -1.3817184711074968 IQS(ph)TPVK ddPTM_PC-9_AZD4547_30min_R2 1 IQSTPVK 7 0 P62820;E7END7;P62820-2;P62820-3 P62820 RAB1A Ras-related protein Rab-1A 1 IQS(0.743)T(0.257)PVK 99.01299999999999 0.011978 60679000.0 433980.0 483300.0 515190.0 359430.0 461410.0 419820.0 465500.0 554090.0 477050.0 416170.0 True False 571976.6126552343 639517.2735533856 508358.24398083356 276568.9666381434 397351.1860163477 393568.5890336045 506928.5982070105 468468.1222215247 502265.88908312237 401600.0149722897 1.4242445003262776 1.5924234305556793 1.2658322336365206 0.6886677199382739 0.9894202470180806 0.9800014301811235 1.26227235883442 1.1665042449110687 1.2506620277834866 1.0 18.615399797511472 -5.522131230235177 24.99998881763358 1.0525108434847152 1.4885324975675305 0.5711677121091263 0.15986300350367794 19.501214876746925 652202.1099543576 0.04682877119890944 0.08237486753063553 3.0051680974319955e-06 5.522131230235177 0.43602165408281524 IQS(ph)TPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IQSTPVK 7 0 P62820;E7END7;P62820-2;P62820-3 P62820 RAB1A Ras-related protein Rab-1A 1 IQS(0.741)T(0.259)PVK 93.598 0.013808 34118000.0 189840.0 209380.0 205600.0 165030.0 234620.0 145570.0 201360.0 126840.0 142860.0 127520.0 True False 221976.16248908764 230165.8626557869 210502.28374234223 155783.9041344789 188647.89523376236 137936.05293866078 182285.72307984516 123510.58439808906 144949.05723543285 150638.36655223576 1.4735698983572993 1.5279365272191396 1.397401528974678 1.0341582141390178 1.252323027336773 0.915676770106437 1.2100882879437973 0.8199145226077594 0.9622320033931723 1.0 17.200729735716635 -5.689643938935377 0.7181961317791251 0.9668731374536773 1.6201048727774157 0.7242212688436758 0.12393800300249896 0.5675638922231402 0.47938727525012403 0.06090121759755212 0.25104179257373954 2.0434125721645866e-06 5.689643938935377 0.6532317353237383 IQS(ph)TPVK ddPTM_PC-9_Lapatinib_30min_R1 1 IQSTPVK 7 0 P62820;E7END7;P62820-2;P62820-3 P62820 RAB1A Ras-related protein Rab-1A 1 IQS(0.724)T(0.276)PVK 86.13600000000001 0.018816 49016000.0 296310.0 479760.0 378110.0 290740.0 340600.0 312340.0 274470.0 223610.0 388620.0 216240.0 True False 292084.5650634016 478649.14519636566 347023.25534680765 312121.9894802075 320566.57764536457 298981.9463001016 288680.71360797546 233999.73692843935 344849.5232499781 253616.79587831107 1.1516767414865847 1.8872927699395283 1.3682976087802732 1.2306834348225424 1.263980078824026 1.178872815834947 1.1382555031824018 0.9226507894245133 1.359726677626831 1.0 17.952290766160047 -5.706010397345827 2.721015132639873 1.1503630234219175 1.5372725715218025 0.3450370206748371 0.20307016034353761 0.26375669338369 3.9579101373346095 0.05591587833820741 0.10470648143385336 1.9678391775508447e-06 5.706010397345827 0.386909548099885 IQSSLSSAS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 3 IQSSLSSASPSK 12 0 Q5W0B1 Q5W0B1 RNF219 RING finger protein 219 1 IQSSLS(0.001)S(0.001)AS(0.917)PS(0.082)K;IQSSLS(0.002)S(0.024)AS(0.913)PS(0.062)K;IQSSLSSAS(0.901)PS(0.099)K 175.01 7.0282e-05 89455500.0 113823.0 81811.0 111955.0 130193.0 120826.0 110404.0 106146.0 119214.0 107866.0 112200.0 True False 150016.34633452384 108254.80584869874 110470.40354990246 100179.01531179863 104051.39550857402 103500.42042700715 115592.78836795107 100792.21556519101 113567.57654719641 108271.9121510219 1.3855518329192817 0.9998420060938862 1.0203052791366058 0.9252539584972419 0.9610192841467421 0.9559304751415189 1.0676156546188795 0.9309174795454068 1.0489107866570964 1.0 16.72429950264528 -4.760657920222221 5.929377353218778 0.9862266715738259 1.4011246587769053 0.8744059071336939 0.04498478694022214 0.042619027842438366 5.604280844634793 0.010831577099789649 0.07198179491871076 1.735170197314418e-05 4.760657920222221 0.41489798720307935 IQSSLSSAS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IQSSLSSASPSK 12 0 Q5W0B1 Q5W0B1 RNF219 RING finger protein 219 1 IQSSLS(0.001)S(0.002)AS(0.915)PS(0.082)K;IQSSLS(0.001)S(0.001)AS(0.567)PS(0.432)K;IQSSLS(0.042)S(0.018)AS(0.47)PS(0.47)K;IQSSLS(0.001)SAS(0.524)PS(0.475)K 150.12 5.7271e-05 81561900.0 86575.0 74835.0 80007.0 100140.0 101307.0 86526.0 89643.0 94179.0 75943.0 66165.0 True False 101230.43756580689 82264.12423271462 81914.67030823724 94529.48045826024 81456.62058838428 81988.42423968251 81151.36608088276 91706.90104089901 77053.52270495919 78160.19073814817 1.2951662043014778 1.0525066975375663 1.0480357012263097 1.2094325713066945 1.0421753045777458 1.048979326500874 1.0382698060801259 1.1733198214438212 0.985841026963502 1.0 16.254146367539533 -4.758116483207731 24.9891890309106 1.073621657081748 1.29516651362372 0.5062176670083184 0.06742127099477484 77.93804496859804 586022.8462029104 0.016112524999082726 0.1130514561360132 1.745353964390134e-05 4.758116483207731 0.22154485654197198 IQSSLSSAS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 2 IQSSLSSASPSK 12 0 Q5W0B1 Q5W0B1 RNF219 RING finger protein 219 1 IQSSLS(0.002)S(0.008)AS(0.986)PS(0.003)K;IQSSLS(0.027)S(0.077)AS(0.885)PS(0.011)K 174.24 0.00039749 93464000.0 243723.0 247794.0 251725.0 257113.0 262174.0 227454.0 167476.0 179220.0 209716.0 212897.0 True False 240247.4653266761 247220.24821741757 231029.14218659975 276021.9477238244 246753.44077391605 217726.32264117076 176147.08781363838 187547.21547477646 186095.57567261698 249695.96278257956 0.9621599910923243 0.9900850837251314 0.9252418005162792 1.1054321609683693 0.988215580356717 0.8719657307024781 0.705446278949319 0.7511023141294497 0.7452886846819304 1.0 17.929812969629097 -6.920674291415057 3.4392119055914594 0.7799219403742578 0.9963693988472537 0.5242251812887917 0.08646628133202942 0.1689613761362802 3.992773797741221 0.03141957628387786 0.026981594168636252 1.2003992311378084e-07 6.920674291415057 0.21644745847299596 IQSSLSSASPS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IQSSLSSASPSK 12 0 Q5W0B1 Q5W0B1 RNF219 RING finger protein 219 1 IQSSLSSAS(0.464)PS(0.535)K 145.49 0.00011076 7647200.0 38672.0 39226.0 29124.0 37902.0 45792.0 50798.0 46360.0 43196.0 38215.0 29913.0 True False 45218.40579318378 43120.09804439723 29818.426613385058 35778.47381994195 36819.386320622456 48134.0634552318 41968.44518266586 42062.15076994517 38773.82207932289 35335.9901088223 1.2796699810569099 1.220288377702242 0.8438542834530713 1.012522182334695 1.0419797551230863 1.3621823898805716 1.1876968793974063 1.1903487249234757 1.0972898158481845 1.0 15.10885071320398 IQST(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IQSTPVK 7 0 P62820;E7END7;P62820-2;P62820-3 P62820 RAB1A Ras-related protein Rab-1A 1 IQS(0.365)T(0.635)PVK 89.08 0.041175 34632000.0 325820.0 315860.0 293960.0 250170.0 354640.0 216440.0 243230.0 191650.0 210170.0 196080.0 True False 380974.89076166594 347216.4933539825 300969.1212495076 236153.78596208373 285150.8378045407 205089.50537915612 220189.49356729578 186619.39056995988 213243.3386474234 231627.75183157416 1.6447722164081966 1.4990280335944268 1.2993655504127775 1.0195401202779908 1.231073718713487 0.8854271725103343 0.9506179282325565 0.8056866635983168 0.9206294883114058 1.0 17.821448590593 -5.076314331184434 0.5818477634092574 0.8910581252565832 2.0151099841533124 0.8780672403123657 0.09304360425992361 0.8727455375087582 0.2849066014148042 0.05085415079973706 0.6309291313452638 8.38852626777862e-06 5.076314331184434 1.1240518588967292 IQST(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 1 IQSTPVK 7 0 P62820;E7END7;P62820-2;P62820-3 P62820 RAB1A Ras-related protein Rab-1A 1 IQS(0.456)T(0.544)PVK 99.788 0.028678 45058000.0 303800.0 488410.0 360250.0 305940.0 305230.0 306880.0 267560.0 246660.0 398350.0 165210.0 True False 299467.7562899035 487279.1166528215 330631.63560521434 328439.8481859223 287276.9715052686 293755.45777221996 281412.9476188652 258120.7240766006 353483.628188536 193766.32837151273 1.5455097839069691 2.514777055167964 1.7063420584162927 1.6950305605017033 1.482594906553969 1.5160294373179004 1.4523315272780806 1.3321237298861321 1.824277887491337 1.0 17.56395836349739 -5.786129329293212 1.855932302860135 1.458761289205258 2.0292088621985447 0.3584284944686599 0.29801990204675505 0.34546255145319543 2.428529223616735 0.08696333130232499 0.1728567249061088 1.6363291636181447e-06 5.786129329293212 0.5704475729932867 IQTLTS(ph)SVR ddPTM_PC-9_AZD4547_30min_R2 1 IQTLTSSVR 9 0 E7EWU0;H0Y4R2;P16435 E7EWU0 POR NADPH--cytochrome P450 reductase 1 IQT(0.1)LT(0.326)S(0.572)S(0.002)VR 72.848 0.031181999999999998 1823900.0 26112.0 27012.0 37091.0 40350.0 35690.0 27428.0 33487.0 34042.0 33293.0 22614.0 True False 34415.07283665947 35743.100751549915 36599.14910517115 31047.9309012856 30735.059554243395 25712.922824100096 36467.27812708515 28781.591107338354 35052.80001099341 21822.29074316589 1.577060503945365 1.6379169892025942 1.6771451510714082 1.422762223576776 1.408424986907881 1.1782870610021838 1.6711022026184692 1.3189078748000787 1.6062841625355455 1.0 14.413514932647278 -13.087017120424058 0.15359787291830435 3.1353685012608496e-19 1.648858092123797 0.47527100578814974 0.15743368333264177 75.12066574583193 1.0174345255324804 25.422094651113383 0.8164999123221974 8.18432523879446e-14 13.087017120424058 1.648858092123797 IQVLQQQADDAEER ddPTM_PC-9_AZD4547_30min_R2 1 IQVLQQQADDAEER 14 0 A0A087WWU8;P06753-5;P06753-2;P06753-4;P06753-3;P06753-6;D6R904;Q5VU61 A0A087WWU8 TPM3 Tropomyosin alpha-3 chain 0 219.89 4.304100000000001e-15 11490000.0 17635.0 18661.0 17131.0 24741.0 23531.0 22698.0 18647.0 26979.0 18740.0 22226.0 False True 23242.563169213 24692.80331425562 16903.83174680345 19037.344694639592 20264.126824625986 21278.69047183257 20306.54687597446 22810.01546574471 19730.558141531754 21447.8745050679 1.0836767607774391 1.1512937241599852 0.7881355209724517 0.8876098510433411 0.9448081589547623 0.992111850841194 0.9467859797098424 1.0635093682758612 0.919930696949464 1.0 14.388547062568636 -5.230283574376552 24.997815727020235 0.9451249599603858 1.1174853006718342 0.49310797978974086 0.07078929150528274 590.0017781763546 473385.31058061525 0.018812471111624256 0.049762125576916796 5.8845929295676735e-06 5.230283574376552 0.17236034071144835 IQVLQQQADDAEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IQVLQQQADDAEER 14 0 A0A087WWU8;P06753-5;P06753-2;P06753-4;P06753-3;P06753-6;D6R904;Q5VU61 A0A087WWU8 TPM3 Tropomyosin alpha-3 chain 0 ; 193.28 7.672399999999999e-07 7204900.0 18441.1 24295.0 23468.0 20213.3 28337.0 17220.4 25713.0 13379.1 14886.3 16135.3 False True 21562.81400167258 26706.847039938562 24027.566122885615 19080.814333402785 22784.568268856543 16317.331909218345 23277.278494001042 13027.912801328215 15103.983975387266 19060.502163035468 1.131282576777537 1.4011617748315075 1.2605946012001146 1.0010656681651708 1.1953813217493952 0.8560809033071004 1.2212311247047456 0.6835031254629581 0.7924231925368063 1.0 14.218298508166537 -6.5718652917183595 0.68306662087909 0.8502952370216831 1.2879098672515277 0.4455213289093106 0.16103884562913298 0.6622405063504017 0.6873942714508807 0.11227357265022861 0.14274819764857366 2.6799994708605694e-07 6.5718652917183595 0.4376146302298446 IQVLQQQADDAEER ddPTM_PC-9_Lapatinib_30min_R1 2 IQVLQQQADDAEER 14 0 A0A087WWU8;P06753-5;P06753-2;P06753-4;P06753-3;P06753-6;D6R904;Q5VU61 A0A087WWU8 TPM3 Tropomyosin alpha-3 chain 0 ; 164.13 0.00076916 29288000.0 55978.0 62169.0 69647.0 56290.0 61468.0 59972.0 58513.0 60974.0 60475.0 55320.0 False True 55179.74345489205 62025.05150015198 63920.89250519459 60429.75437793531 57852.57309073768 57407.13736156016 61542.516833692156 63807.07463653071 53663.66867001807 64881.98829073344 0.8504632010910942 0.9559671818659495 0.9851870170619276 0.9313795087035888 0.8916584496686931 0.8847931278604042 0.948530069052797 0.9834327880121971 0.8270965499631955 1.0 15.98553041077585 -10.772832836022362 4.980754312168049 1.000014285977205 0.9222491712392813 0.18441467100080444 0.051148367098720726 8.035512349503715e-06 1.2100764522714717e-06 0.04904458126994733 0.011892873290029509 1.687202320256272e-11 10.772832836022362 -0.07776511473792369 IQVWHAEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IQVWHAEHR 9 0 P15311;E7EQR4 P15311 EZR Ezrin 0 125.75 0.001189 4492500.0 17940.0 17900.0 21844.0 24095.0 25893.0 19710.0 20398.0 21155.0 25294.0 19462.0 False True 20976.887668848725 19676.993703021224 22364.843803831314 22745.035267043997 20819.452524455748 18676.372902528026 18465.75377126873 20599.703665575285 25663.876898453313 22990.306538892753 0.9124231394375746 0.855882181028496 0.9727945021523161 0.9893315353828002 0.9055752470823054 0.8123585856035962 0.8031973710324468 0.8960169204671856 1.116291201034561 1.0 14.488738081760049 -8.247167960733435 23.738016136190502 1.058145582997625 0.8927292460522841 0.5273129696854035 0.06237071200171854 299.0774570769529 497466.9983766214 0.04700702334058872 0.017548903205565347 5.660203417990083e-09 8.247167960733435 -0.16541633694534086 IQVWHEEHR ddPTM_PC-9_AZD4547_30min_R2 3 IQVWHEEHR 9 0 P26038 P26038 MSN Moesin 0 ;; 94.309 0.0024349 57601000.0 25895.699999999997 29232.899999999998 35521.3 59845.6 45222.9 45072.4 34584.9 43329.3 36318.2 36892.1 False True 34129.993935978986 38681.863244483306 35050.2643527949 46049.12152530303 38944.48093907517 42254.01570282082 37662.889100171014 36633.75229326115 38237.905906925174 35600.518808081295 0.9586937235372958 1.0865533576354103 0.9845436394269206 1.293495799135655 1.093930151664947 1.1868932565451598 1.0579309055356116 1.0290229895454588 1.074082827642534 1.0 15.11961064535888 -10.56691719670668 12.061646679203259 1.00000041479034 1.08905323680871 0.0702809997096383 0.0917124126460698 0.0 0.0 0.08947131046793154 0.021699980207159582 2.7107084107052562e-11 10.56691719670668 0.08905282201836995 IQVWHEEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IQVWHEEHR 9 0 P26038 P26038 MSN Moesin 0 ;;; 93.178 0.0027161 71347000.0 73423.5 60993.7 79626.40000000001 72436.6 92748.7 73821.6 92647.9 82516.8 79467.8 55312.299999999996 False True 85852.64836977232 67048.75144267964 81524.99536080378 68378.21214462575 74575.25803711396 69950.26534050051 83871.62019929061 80350.82143377651 80629.86623669277 65339.982138074105 1.3139374324950317 1.0261519707947673 1.2477045859689413 1.0464987884467334 1.1413418797624433 1.0705583786766901 1.2836186582061826 1.2297343648484942 1.2340050241567044 1.0 15.995678439937372 -7.255470800137587 24.944816426592343 1.2059840412928988 1.1363762007739846 0.0282527904256189 0.10877122446141502 1211.6876220264164 5064085.812856848 0.03935740986413416 0.029694086435708606 5.553019516844134e-08 7.255470800137587 -0.06960784051891422 IQVWHEEHR ddPTM_PC-9_Lapatinib_30min_R1 3 IQVWHEEHR 9 0 P26038 P26038 MSN Moesin 0 ;; 82.287 0.006728100000000001 58599000.0 47029.0 50288.0 56423.0 48488.0 52443.0 47998.6 42377.0 40438.0 54084.0 35288.5 False True 46358.35783593765 50171.56122568554 51784.11873907849 52053.969271226284 49358.405846905 45945.81176820151 44571.073707746546 42316.897106176875 47992.490390231644 41388.07020602941 1.1200898617685286 1.212222772792546 1.2511846645977367 1.2577046721942369 1.1925756770296208 1.1101221086048154 1.0769063038182785 1.0224418992121105 1.1595730400408981 1.0 15.33692736140837 -6.842303919874801 2.545136226879421 1.0678633375489919 1.2148086290955713 0.6263357673889738 0.05232395288640903 0.18762609739110925 2.477746827335126 0.020381489419506727 0.0179717352371379 1.4377920572585163e-07 6.842303919874801 0.14694529154657943 IQYQLVDISQDNALRDEMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IQYQLVDISQDNALRDEMR 19 1 Q5T123;Q9H299 Q5T123 SH3BGRL3 SH3 domain-binding glutamic acid-rich-like protein 3 0 100.69 0.0026261999999999995 10636000.0 17595.0 13335.0 20434.0 20202.0 21097.0 17471.0 18995.0 16543.0 13169.0 13866.0 False True 20573.485982909315 14658.810672055195 20921.224056376548 19070.147435767685 16963.194296081678 16554.790004062277 17195.65608810911 16108.763778757373 13361.571711699677 16379.796036804402 1.256028215289247 0.8949324301180395 1.2772579102552823 1.1642481623652838 1.035616942846322 1.010683525415376 1.0498089261594907 0.9834532580602324 0.8157349262272278 1.0 13.999629772027586 -7.142829709139788 0.9053637757061123 0.9250014084859193 1.134121332607041 0.360793523171857 0.11156981408760559 0.6848904363759062 1.124774174426903 0.08082926204115548 0.05179275394906301 7.197311358789037e-08 7.142829709139788 0.20911992412112168 IRAAGS(ph)AAGSVCRAGAPGR ddPTM_PC-9_Lapatinib_30min_R1 1 IRAAGSAAGSVCRAGAPGR 19 2 A0A087WTW0;A0A087WWG9 A0A087WTW0 UHRF1 1 IRAAGS(1)AAGSVCRAGAPGR 84.859 0.017464 4704300.0 38180.0 33781.0 45122.0 41299.0 37945.0 37384.0 27978.0 32522.0 39781.0 28627.0 True False 37635.54619864549 33702.782169998434 41412.24333595693 44336.2662294253 35713.149702740324 35785.17346636037 29426.563942594606 34033.09084739809 35300.4448674988 33575.13880692021 1.1209349398397241 1.003801722572534 1.2334198698062095 1.3205087992156597 1.063678393352746 1.065823544979199 0.8764390852355751 1.0136396171915003 1.0513864163153657 1.0 15.035105743629314 -6.704358274276634 2.682740735098368 0.989071732111711 1.162777877321839 0.4294015277968366 0.09005733648601565 0.2819841231239096 4.142522861307811 0.03557098112598078 0.03412046454820386 1.9753393976839117e-07 6.704358274276634 0.17370614521012795 IRAENGTGSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 IRAENGTGSSPR 12 1 M0R102;M0R050;Q9NQT4 M0R102 EXOSC5 Exosome complex component RRP46 1 IRAENGTGSS(1)PR 157.33 0.0020119 29973000.0 29423.0 24222.0 38237.0 64962.0 53582.0 32108.0 28228.0 37933.0 25347.0 34531.0 True False 38778.90196358121 32051.287812973555 37729.95239638801 49986.01455289508 46143.06419264417 30100.28168427176 30740.237315118095 32071.326463623343 26686.790673073916 33322.08020041841 1.1637599372650895 0.9618633536741533 1.1322808230896177 1.500086856890388 1.3847594122309559 0.9033134037020235 0.9225185561714153 0.9624647162100234 0.8008740904698628 1.0 15.024190846313862 -6.779799788736581 24.96725852915912 0.9157808603714949 1.2234712240685985 0.5399387214818571 0.14336198975824407 219.8889964862202 299012.36818125244 0.05716885146678839 0.05051011140589247 1.6603521591399424e-07 6.779799788736581 0.3076903636971037 IRAENGTGSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 IRAENGTGSSPR 12 1 M0R102;M0R050;Q9NQT4 M0R102 EXOSC5 Exosome complex component RRP46 1 IRAENGT(0.012)GS(0.335)S(0.653)PR 89.189 0.036811 3549200.0 39484.0 19282.0 42653.0 25982.0 34103.0 26043.0 18686.0 17578.0 43182.0 17985.0 True False 38920.9509195212 19237.353713682554 39146.234985341325 27892.802953411203 32097.12858907768 24929.201599198135 19653.469648699793 18394.738051643937 38318.388433381064 21093.683286493884 1.8451472125990425 0.9119959493276396 1.8558273798680929 1.322329655497897 1.5216464641634786 1.1818325543533739 0.931722989378709 0.8720495990106166 1.8165811969840289 1.0 14.364523413760736 -6.818021903833824 5.788623346717531 1.1341415201766811 1.4700147794461227 0.1807864357839143 0.34927835891645465 0.3511095650172168 24.183142260076735 0.11854379075390602 0.1056033320145535 1.520470842180806e-07 6.818021903833824 0.33587325926944156 IRDIDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IRDIDLK 7 1 B4DJK0;B4DUA4;Q13243-3;Q13243;G3V5K8;Q13243-2 B4DJK0 SRSF5 Serine/arginine-rich splicing factor 5 0 82.241 0.029514 3307300.0 23436.0 18403.0 22357.0 27871.0 26596.0 26504.0 26237.0 20724.0 24878.0 22079.0 False True 27403.25191790071 20229.928218810022 22890.075669394646 26309.47822900116 21384.704720983464 25114.08358237458 23751.641420569555 20180.016958893048 25241.793685447985 26081.747922732164 1.0506677696250855 0.7756354473918579 0.8776281304921385 1.0087314050785114 0.819910720107264 0.9628987925493218 0.9106614131435666 0.7737218003439362 0.9677953241564727 1.0 14.670752937575362 -8.508196270251267 24.164991878786363 1.0000000668263196 0.8948921683357058 0.13894823453021388 0.08770613886738618 728.9523061810372 1199738.0293233872 0.08006795125489119 0.02067345608742159 3.103156864748218e-09 8.508196270251267 -0.10510789849061375 IRDT(ph)SQEPCGR ddPTM_PC-9_Lapatinib_30min_R1 1 IRDTSQEPCGR 11 1 Q12955;A0A087WTF3;A0A087WZ65;Q12955-7;Q12955-6;Q12955-5;Q12955-4 Q12955;Q12955-6 ANK3 Ankyrin-3 1 IRDT(0.646)S(0.354)QEPCGR 74.53699999999999 0.016382 6271400.0 8156.8 7177.8 9202.4 7712.7 11674.0 7981.7 11349.0 9076.7 8954.1 8517.1 True False 8040.482536226078 7161.180245102713 8445.814194291263 8279.917686812963 10987.358271967067 7640.341297251461 11936.595688916515 9498.436618122454 7945.594967146901 9989.269386677623 0.8049119735372658 0.7168872885391755 0.8454886806391648 0.8288812090557526 1.0999161046372985 0.7648548659065243 1.194941814747331 0.9508639971998576 0.7954130236735525 1.0 13.286163448088924 -6.068677662796308 7.7185986022943185 0.9667206541833746 0.7907100703357002 0.3163809740342317 0.1224542103519731 0.35819141504858676 36.376895334316444 0.0353471865673905 0.045913934129694 8.537335274972015e-07 6.068677662796308 -0.17601058384767443 IREEFPDR ddPTM_PC-9_AZD4547_30min_R2 1 IREEFPDR 8 1 P04350;K7ESM5;Q9BUF5;M0R042;M0QYM7;K7ES63 P04350 TUBB4A;TUBB6 Tubulin beta-4A chain;Tubulin beta-6 chain 0 96.03399999999999 0.015350999999999998 0.0 17203.0 18698.0 17864.0 28406.0 21843.0 17691.0 18113.0 25372.0 20269.0 22510.0 False True 22673.19615537122 24741.762840681182 17627.111687869747 21857.435568325127 18810.476487625056 16584.77897335404 19725.021910469535 21451.34039055838 21340.37796001636 21721.93175151075 1.0437928087953923 1.13902221605868 0.8114891386970585 1.0062381107888783 0.865967019085068 0.7635038707918128 0.9080694174033426 0.9875429421265192 0.982434628933596 1.0 14.406864788603283 -5.2511561348640186 24.98108500474513 0.9109663113139457 1.0914075257572442 0.4266311121671935 0.08135352286925125 652.5958525818229 1585343.2766946997 0.02135283950670773 0.055136265036519395 5.60846307790229e-06 5.2511561348640186 0.18044121444329853 IREEFPDR ddPTM_PC-9_Lapatinib_30min_R1 2 IREEFPDR 8 1 P04350;K7ESM5;Q9BUF5;M0R042;M0QYM7;K7ES63 P04350 TUBB4A;TUBB6 Tubulin beta-4A chain;Tubulin beta-6 chain 0 ; 96.03399999999999 0.015350999999999998 7090300.0 65051.0 69213.0 70426.0 60713.0 67256.0 65034.0 54566.0 52642.0 71817.0 48186.0 False True 64123.36081110763 69052.74155093408 64635.8461322217 65178.036552630816 63300.13431038353 62252.647421658534 57391.1604865115 55087.93949906924 63728.21319346319 56514.88589619095 1.1346278028215835 1.2218504993139898 1.1436959503191368 1.1532897133040794 1.1200612600838658 1.101526552420312 1.0155051996730584 0.9747509638479535 1.1276358818192078 1.0 15.786343299821084 -6.817988952494636 1.428170683864172 1.0272272956109416 1.1675663350587127 0.6417997088645182 0.04429939108930349 0.2487267132274178 1.0557746183220924 0.020461420416073666 0.017628828421736114 1.5205862096405962e-07 6.817988952494636 0.14033903944777104 IREHLEK ddPTM_PC-9_AZD4547_30min_R2 1 IREHLEK 7 1 P05783;F8VZY9;CON__P05784 P05783 KRT18 Keratin, type I cytoskeletal 18 0 81.296 0.031305 22607000.0 69027.0 55677.0 71591.0 100520.0 118250.0 110250.0 111240.0 116610.0 99806.0 128760.0 False True 90976.15014920714 73673.50142692302 70641.65656327164 77346.66701851872 101833.02864357732 103356.05007135165 121140.14449956531 98590.6039312239 105081.54140201259 124252.15159149405 0.7321897366277487 0.5929354178842766 0.568534674518325 0.6224976069051319 0.8195675273163521 0.8318250327862098 0.9749540989667516 0.7934720056628229 0.845712046480217 1.0 16.92291130862681 -6.372259586101456 2.696180633434017 0.880148923342697 0.6195204370273334 0.7490335953694403 0.07118790333027578 0.14280246640687586 2.018030829822765 0.023790103889011743 0.02783709915777538 4.2436583656439406e-07 6.372259586101456 -0.2606284863153636 IREHLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IREHLEK 7 1 P05783;F8VZY9;CON__P05784 P05783 KRT18 Keratin, type I cytoskeletal 18 0 76.47800000000001 0.040441000000000005 8350100.0 42971.0 47293.0 62181.0 67764.0 68016.0 73933.0 90335.0 83941.0 77058.0 72712.0 False True 50245.14158406346 51987.9364914515 63663.63086275566 63967.40277385222 54688.753056941314 70055.82332839195 81777.81483123658 81737.63769284128 78184.82747058666 85894.11001212476 0.5849660887920125 0.6052561285530861 0.7411873858844215 0.7447239719326811 0.6366996881302045 0.8156068363535395 0.9520770960860165 0.9516093441250307 0.9102466683635251 1.0 16.390271584863846 -7.007387986880272 2.665637589258168 0.9502150780576809 0.667551774521342 0.8685634803131881 0.05322389037660384 0.1068777138557109 1.5285434104308644 0.023758256175696556 0.018947792050040806 9.831324095577539e-08 7.007387986880272 -0.28266330353633895 IRETTDFK ddPTM_PC-9_Lapatinib_30min_R1 2 IRETTDFK 8 1 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 100.02 0.011739 0.0 49823.0 69532.0 59695.0 56578.0 59827.0 58896.0 55477.0 53897.0 60487.0 51628.0 False True 49112.51488358081 69371.00292603343 54787.10752936374 60738.934858675144 56308.09348440757 56377.15537328166 58349.32760895425 56401.25138067203 53674.31710365249 60551.831010014226 0.8110822425082149 1.1456466595462764 0.9047968759244109 1.0030899783795137 0.9299156201419438 0.9310561618517837 0.9636261469831404 0.9314541020459685 0.8864193899400942 1.0 15.885882965383633 -6.28459004098035 23.831712789358697 0.9376775306443509 0.9745922067835677 0.01794137354039027 0.0830700220769342 1581.3463260285216 1627861.0072459946 0.024075643038428896 0.02732135774892275 5.192899994978763e-07 6.28459004098035 0.03691467613921684 IRIDS(ph)LSAQLSQLQK ddPTM_PC-9_AZD4547_30min_R2 2 IRIDSLSAQLSQLQK 15 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 IRIDS(0.98)LS(0.02)AQLSQLQK;IRIDS(0.483)LS(0.483)AQLS(0.033)QLQK 92.671 0.0016599 17219600.0 105825.0 68154.0 140844.0 203764.0 160644.0 130921.0 110215.0 136513.0 111728.0 121638.0 True False 139475.14870325872 90183.44767588972 138976.31653416515 156789.35792241778 138341.35351728424 122734.4891736186 120023.92148525384 115418.05260666482 117633.71398276731 117379.49064372556 1.1882412160621714 0.7683066878320145 1.1839914773185638 1.3357474722591058 1.1785819887154128 1.0456212452492806 1.0225289002961748 0.9832897721202917 1.00216582417974 1.0 16.84082082725093 -6.959016411760466 4.8061288009152925 1.0042112961905125 1.1249980423312302 0.16956302127669654 0.1352469612758588 0.43240686396743183 23.06448106629777 0.05385042815605901 0.04632958109078193 1.0989643093635334e-07 6.959016411760466 0.12078674614071772 IRIDS(ph)LSAQLSQLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IRIDSLSAQLSQLQK 15 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 IRIDS(0.94)LS(0.06)AQLSQLQK 111.93 0.00017535 3446400.0 30904.0 22683.0 32117.0 46864.0 47184.0 45787.0 47501.0 53208.0 42293.0 28389.0 True False 36135.43681817729 24934.818333275434 32882.79108440077 44238.36201513796 37938.633913178084 43385.84911659315 43001.361402541224 51811.34637853604 42911.455114504846 33535.700972799656 1.0775214404340687 0.743530554303896 0.9805309008173573 1.319142308998374 1.1312909172213095 1.2937212540087595 1.2822562271001592 1.5449608887125845 1.2795753143585618 1.0 15.033410137541077 -5.683933208589269 4.575758223262403 1.2838504339689685 0.9007945609544608 0.49711928535118866 0.1519704377679389 0.15440216206042504 5.95341427557554 0.04140754562371222 0.0728546351826494 2.0704597463293436e-06 5.683933208589269 -0.3830558730145077 IRIDS(ph)LSAQLSQLQK ddPTM_PC-9_Lapatinib_30min_R1 1 IRIDSLSAQLSQLQK 15 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 IRIDS(0.599)LS(0.4)AQLS(0.001)QLQK 68.525 0.013028999999999999 4148500.0 57590.0 34033.0 42042.0 31148.0 32471.0 34433.0 25445.0 24918.0 38927.0 26497.0 True False 56768.75603928743 33954.19867948127 38585.46904681315 33438.72782668201 30561.11962044225 32960.38085724339 26762.417596658823 26075.781247631312 34542.63134051746 31076.971144966807 1.8267145718440336 1.0925839111248283 1.2416097072916457 1.0759970033983737 0.9834008429547966 1.0606046742293809 0.8611655708601201 0.8390708710316037 1.1115185961779916 1.0 14.923558280750935 -1.7836696834771857 0.8748355359972045 0.981594930738689 199.99999999999594 0.8213499761515246 0.11169578576632186 184.41281376770362 0.7680392083199151 0.03799291530040633 72732.03593389296 0.016456228783294394 1.7836696834771857 199.01840506925726 IRIDSLS(ph)AQLSQLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IRIDSLSAQLSQLQK 15 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 IRIDS(0.489)LS(0.511)AQLSQLQK 100.45 0.0008801999999999999 4454500.0 38019.0 26128.0 32008.0 40542.0 39353.0 49612.0 46422.0 43987.0 39045.0 36782.0 True False 44454.86579052168 28721.815166063603 32771.19211101597 38270.563178937424 31642.062147874207 47010.259383065495 42024.57209382474 42832.387858078975 39615.95925911715 43450.285433848185 1.0231202245656807 0.6610270767908244 0.7542227118601825 0.8807896840448438 0.7282360019486717 1.0819321188266362 0.9671874804552423 0.9857792056001579 0.9117537172323371 1.0 15.407078033980257 -6.757479579276203 24.99998330521965 0.9870577681650625 0.8021236945125633 0.45138271424750886 0.09895748054224915 91.75218604249808 579272.5068350856 0.032208876464218605 0.031077349254928163 1.7479154482642814e-07 6.757479579276203 -0.18493407365249925 IRLDETDDPDDYGDR ddPTM_PC-9_AZD4547_30min_R2 2 IRLDETDDPDDYGDR 15 1 P07384 P07384 CAPN1 Calpain-1 catalytic subunit 0 ; 169.4 7.031399999999999e-05 19630500.0 27348.0 34585.0 39432.0 37641.0 32254.0 40479.0 35261.0 46212.0 36998.0 30993.0 False True 36044.09512626237 45763.92490346338 38909.10591558888 28963.44899765281 27776.088844566166 37947.84173095915 38399.16069039178 39070.99724611712 38953.638747086 29907.944503534993 1.2051679152340982 1.530159483145165 1.3009622212917369 0.968419912449331 0.9287194190588106 1.2688214573379952 1.283911727395815 1.306375208817814 1.3024512180194077 1.0 14.86824114067678 -14.522877948380732 0.02174697289532084 7.276728854024576e-07 2.0466142283629374 0.0924686864308607 0.17018374666664193 9222.096622106494 15.11436114235992 984.4515146705555 509.87938791441957 3.0000055047925107e-15 14.522877948380732 2.046613500690052 IRLDETDDPDDYGDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IRLDETDDPDDYGDR 15 1 P07384 P07384 CAPN1 Calpain-1 catalytic subunit 0 ; 214.58 1.5467e-17 14761200.0 50017.0 69834.0 68819.0 62740.0 72179.0 50217.0 56551.0 32477.0 43561.0 53400.0 False True 58483.89021921997 76766.65800317237 70459.90595751081 59224.881205824444 58036.04309128686 47583.53211802387 51194.07988621522 31624.513162225903 44197.99721568455 63080.997285832564 0.9271237414687312 1.2169537785734006 1.1169751428983112 0.9388704008191994 0.920024184594197 0.7543243475117143 0.8115610419766297 0.5013318514754758 0.7006546997888226 1.0 15.944917848301076 -6.433155319415472 1.2389368131310035 0.7120695870907082 1.0961211168955347 0.5092468328476573 0.13774872748719377 0.32469746300986574 1.0324194887257672 0.05811434239701754 0.07128623755590845 3.6884566242869127e-07 6.433155319415472 0.3840515298048265 IRLDETDDPDDYGDR ddPTM_PC-9_Lapatinib_30min_R1 2 IRLDETDDPDDYGDR 15 1 P07384 P07384 CAPN1 Calpain-1 catalytic subunit 0 ; 229.9 1.3585000000000001e-24 23340000.0 58374.0 80439.0 72218.0 59675.0 69141.0 77735.0 69495.0 78047.0 68683.0 60844.0 False True 57541.57605551943 80252.74843765746 66280.5148095418 64063.69856996435 65074.262316436136 74410.45525913555 73093.11105835345 81673.3485445816 60947.197275946266 71360.80433046608 0.8063470779988559 1.1246054355835664 0.9288084044372892 0.8977435045895863 0.9119048324495127 1.0427356580027711 1.024275325147194 1.1445127239087576 0.8540710526986881 1.0 16.12284425597688 -6.765942558881189 24.99705442078623 1.0228482765953661 0.9421880600867266 0.13063973781844163 0.0995026957902095 237.6577519540609 1319224.3317618272 0.03344893790035982 0.03048790616618828 1.7141840157455402e-07 6.765942558881189 -0.08066021650863953 IRMEPDET(ph)VK ddPTM_PC-9_Lapatinib_30min_R1 1 IRMEPDETVK 10 1 A0A494C0B4;P54725-2;P54725-3;P54725;K7ENJ0;K7ELW1 A0A494C0B4 RAD23A UV excision repair protein RAD23 homolog A 1 IRMEPDET(1)VK 78.548 0.014593 7679200.0 34963.0 37477.0 47195.0 40064.0 43430.0 43085.0 37150.0 33045.0 45868.0 37663.0 True False 34464.421208571075 37390.22430908 43314.809277968365 43010.440209586086 40875.53278666522 41242.35498604045 39073.445223653944 34580.391336703484 40701.86282854712 44172.99936720707 0.780214649271849 0.84644975085929 0.9805720666123522 0.973681679435967 0.9253510826120219 0.9336553002252717 0.8845549494803174 0.7828400115925817 0.9214194963352017 1.0 15.430877174917862 -13.144780693365789 0.00888186588236281 1.9256540302989604 3.05367174785303e-06 0.13277059699922 0.06922248741315681 43843.09843652239 37.24583574079895 4487.888513353274 3627.815596336739 7.165051340393185e-14 13.144780693365789 -1.9256509766272125 IRPLS(ph)DGNSPWSTILIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IRPLSDGNSPWSTILIK 17 1 Q5TCX8;Q5TCX8-3 Q5TCX8 MLK4 Mitogen-activated protein kinase kinase kinase MLK4 1 IRPLS(0.998)DGNS(0.002)PWSTILIK 87.49600000000001 0.0053453 0.0 8145.8 8592.4 10566.0 8513.5 10195.0 8082.5 8659.8 8311.7 9965.8 8241.1 True False 9524.723053116375 9445.396686806675 10817.93351177814 8036.516196139402 8197.362935419862 7658.639471571931 7839.481052477351 8093.526681974104 10111.530971558705 9735.146193488294 0.9783852100225605 0.9702367585526934 1.1112245565468866 0.825515717628865 0.842037990236137 0.7866999960097867 0.8052761506263844 0.8313718685999552 1.0386624679886338 1.0 13.248986928840006 -5.776003137752925 24.99997857062299 0.8605865914352212 1.0149776497004297 0.3602470836193552 0.08642763979121257 227.33866461115815 390246.4347243396 0.024327587515613463 0.036262288779504444 1.6749307747031609e-06 5.776003137752925 0.1543910582652085 IRPVS(ph)LPVDR ddPTM_PC-9_AZD4547_30min_R2 4 IRPVSLPVDR 10 1 Q52LW3 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 IRPVS(1)LPVDR;IRPVS(1)LPVDR;IRPVS(1)LPVDR;IRPVS(1)LPVDR 82.925 0.0067223 143776000.0 136662.0 123002.0 176226.0 242826.0 191516.0 170210.0 111675.0 132917.0 104677.0 147896.0 True False 180117.67325381277 162759.9910647911 173889.12809597718 186846.21732430198 164927.30920679387 159566.74179269676 121613.85865685908 112377.7317788055 110210.01251766903 142718.20605603894 1.262051130204711 1.1404290704220503 1.2184088694871826 1.3091967905687938 1.1556150666722536 1.1180545650219438 0.8521257519808431 0.7874099239635893 0.7722211171460114 1.0 17.122809860486463 -7.150868691360117 2.323315880585049 0.8269033830172238 1.2182707408347089 0.8443280020224075 0.07390979180512021 0.10818956930497034 1.142615758235729 0.032896171542164794 0.023442138231807415 7.065311411802228e-08 7.150868691360117 0.3913673578174851 IRPVS(ph)LPVDR ddPTM_PC-9_Lapatinib_30min_R1 2 IRPVSLPVDR 10 1 Q52LW3 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 IRPVS(1)LPVDR;IRPVS(1)LPVDR 68.277 0.019537 63961000.0 134742.0 115938.0 131947.0 101075.0 135236.0 143615.0 120133.0 117195.0 115448.0 88735.0 True False 132820.5543713433 115669.55268420973 121098.82699014926 108508.39267631562 127281.68436420575 137472.92123291644 126352.89892471665 122640.30754138187 102445.03051866454 104072.72651804474 1.2762282570574732 1.1114300216219881 1.1635981014598713 1.0426208316691097 1.2230071088042158 1.3209312932632795 1.2140827203446893 1.1784096722028108 0.9843600138687826 1.0 16.667232517402404 -8.248739664080825 6.795879053839303 0.9911232763470508 1.1891884904780199 0.5351268464838992 0.0742249254730381 0.11473064226253292 30.319268668479463 0.06051756755385152 0.020314708179692925 5.639756272301061e-09 8.248739664080825 0.19806521413096911 IRQEVGPPLPPLLAPLIAT(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 2 IRQEVGPPLPPLLAPLIATPPR 22 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 IRQEVGPPLPPLLAPLIAT(1)PPR;IRQEVGPPLPPLLAPLIAT(1)PPR 132.8 4.7081e-06 22570000.0 72078.0 64152.0 95353.0 133433.0 112386.0 99077.0 74911.0 112075.0 94367.0 95721.0 True False 94997.30468446485 84887.87943926526 94088.55691745659 102672.08336929965 96783.14382356947 92881.69952761299 81577.93387816401 94756.38397729101 99355.04696595111 92369.83692520505 1.028445083879355 0.9189999924759186 1.0186069397702113 1.1115325823562585 1.0477786585456248 1.0055414475054494 0.8831663732850411 1.0258368654912582 1.0756221973889835 1.0 16.49513420064234 -5.469603613648114 24.81293081609387 1.0208037780048842 0.9724927011631812 0.08693791358481007 0.06131205533734042 774.9237620304798 360918.90927112824 0.017257033680116274 0.03592297602793862 3.391535648880665e-06 5.469603613648114 -0.04831107684170299 IRQEVGPPLPPLLAPLIAT(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IRQEVGPPLPPLLAPLIATPPR 22 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 IRQEVGPPLPPLLAPLIAT(1)PPR;IRQEVGPPLPPLLAPLIAT(1)PPR 123.88 6.638800000000001e-07 26003000.0 64534.0 56373.0 73971.0 92211.0 95117.0 84163.0 85277.0 93520.0 77693.0 64038.0 True False 75458.33159540042 61969.3388838221 75734.74917657972 87044.71662209577 76479.50665309756 79749.34411950628 77198.94520798516 91065.19909263046 78829.11314428442 75647.58247547105 0.9974982560727305 0.8191846567458496 1.0011522734535097 1.150660917026929 1.0109973663453986 1.0542219792068734 1.020507763523271 1.2038084511446034 1.0420572682523594 1.0 16.207006357478853 -5.518104620610229 23.321089086602864 1.0726196391471121 0.9087981640435803 0.43918832058900337 0.0722899224967658 65.75980524747881 321227.919751512 0.018646515682012636 0.033547436436542316 3.0331604143319893e-06 5.518104620610229 -0.16382147510353184 IRQEVGPPLPPLLAPLIAT(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 3 IRQEVGPPLPPLLAPLIATPPR 22 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 IRQEVGPPLPPLLAPLIAT(1)PPR;IRQEVGPPLPPLLAPLIAT(1)PPR;IRQEVGPPLPPLLAPLIAT(1)PPR 142.01 4.6077e-06 21480500.0 70487.4 51530.3 67318.8 54211.75 54509.67 56195.39 41642.12 40553.23 53515.1 40494.41 True False 69482.23675019389 51410.984756362166 61784.10812208283 58198.66294009659 51303.51838073456 53792.04416755229 43798.145217142 42437.48111264465 47487.66589901422 47493.8148130904 1.462974432010523 1.0824774754078526 1.300887460087828 1.2253945733593858 1.0802147307525636 1.13261157014336 0.9221862970895783 0.8935370064429504 0.9998705323187791 1.0 15.53545202100344 -6.628470575096616 0.9664144560154431 0.9423118433918884 1.277955507554329 0.6572349416080359 0.09846540608540064 0.33034406663019195 0.6694752239660466 0.052443163099807615 0.05517774140680378 2.3524988776549486e-07 6.628470575096616 0.3356436641624405 IRQEVGPPLPPLLAPLIATPPR ddPTM_PC-9_AZD4547_30min_R2 1 IRQEVGPPLPPLLAPLIATPPR 22 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 0 81.37899999999999 0.00055557 1981300.0 6049.3 6587.9 7719.7 13292.0 10297.0 9270.3 8300.6 9383.4 8611.0 9275.5 False True 7972.851566743416 8717.309841593942 7617.331734037621 10227.734759352872 8867.439289157868 8690.626675523372 9039.337319607095 7933.411139081098 9066.159880295081 8950.767568242472 0.8907450121966383 0.9739175746807632 0.8510255322754763 1.142665663181905 0.9906903761661453 0.9709364710081305 1.0098952129735632 0.8863386384011379 1.0128918901281745 1.0 13.12779568987862 IRQEVGPPLPPLLAPLIATPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IRQEVGPPLPPLLAPLIATPPR 22 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 0 72.771 0.0016480999999999998 1113800.0 5574.0 5594.9 6189.3 8363.3 8058.6 7965.4 10557.0 8418.0 6863.8 4400.8 False True 6517.568108481759 6150.324696594042 6336.876385050959 7894.731415184432 6479.575179144136 7547.6804017147 9556.964533938823 8197.036419608261 6964.170089966155 5198.630203286367 1.253708737421179 1.1830663955874474 1.2189511731465412 1.518617617808956 1.246400479697134 1.4518594526964732 1.838362060816961 1.576768513833975 1.33961636385748 1.0 12.343915819596763 -5.752074583325972 24.461040519219317 1.4595109957997827 1.215024399172832 0.15629841514380405 0.20839961509384755 238.86428453841734 623909.7704626907 0.05746240772765914 0.09775553972744419 1.7698049957221096e-06 5.752074583325972 -0.24448659662695071 IRQEVGPPLPPLLAPLIATPPR ddPTM_PC-9_Lapatinib_30min_R1 1 IRQEVGPPLPPLLAPLIATPPR 22 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 0 86.959 0.000286 2237300.0 9046.2 7689.3 6956.4 7279.9 7361.5 6464.4 6185.0 6120.8 7779.4 5052.8 False True 8917.1995291301 7671.4958982791795 6384.471644480536 7815.288131034494 6928.511043265857 6187.932681252413 6505.229036562576 6405.194713078967 6903.202051286289 5926.169747567205 1.5047155091685929 1.2945116702788442 1.0773352631523037 1.3187756112188322 1.1691381344771856 1.0441706776611768 1.0977122346576529 1.0808321370997531 1.1648674177988527 1.0 12.532884235710867 -1.5228787452805037 0.5365008043936613 1.0933866848743379 17.308824409581295 0.7026883781439159 0.08012286842907314 73.28695251063829 0.7001198258511592 0.04157947731272378 1361.9759696657084 0.029999999999988522 1.5228787452805037 16.215437724706955 IRS(ph)IEALLEAGQAR ddPTM_PC-9_AZD4547_30min_R2 2 IRSIEALLEAGQAR 14 1 Q9P2E9;A0A087WVV2;Q9P2E9-3;F8W7S5 Q9P2E9 RRBP1 Ribosome-binding protein 1 1 IRS(1)IEALLEAGQAR;IRS(1)IEALLEAGQAR 97.273 0.001294 1878400.0 5938.200000000001 6499.0 7262.2 11563.3 9857.1 9404.099999999999 6912.6 7485.299999999999 7338.2 5649.9 True False 7826.424077766983 8599.674655128201 7165.898482962813 8897.559836204106 8488.611810931146 8816.06014037187 7527.808008519383 6328.618880082242 7726.082270767778 5452.098720695719 1.435488328202591 1.5773145527399464 1.3143376248419074 1.6319513442465192 1.556943893680625 1.6170030280095316 1.380717480397859 1.160767477679618 1.4170840746958973 1.0 12.412595969800204 -8.364398080922276 0.7095634159633403 1.022410649590915 1.5223058847853965 0.5880778414881895 0.1255423108301555 0.47831165585306706 0.551406630438026 0.12333547472325497 0.05023355272052691 4.321175639243521e-09 8.364398080922276 0.4998952351944814 IRSS(ph)VGPVR ddPTM_PC-9_Lapatinib_30min_R1 1 IRSSVGPVR 9 1 Q9NTI2 Q9NTI2 ATP8A2 Phospholipid-transporting ATPase IB 1 IRS(0.061)S(0.939)VGPVR 64.945 0.024755000000000003 2038200.0 13197.0 12286.0 21231.0 16298.0 17690.0 17344.0 18446.0 15500.0 19534.0 18485.0 True False 13008.8083599666 12257.552521849595 19485.469134030005 17496.60928853419 16649.50897987815 16602.237550838705 19401.04362302883 16220.18658553196 17333.875217860816 21680.10762028575 0.6000343073848238 0.5653824573444639 0.8987717900347387 0.8070351676743004 0.7679624691668713 0.765782063521873 0.8948776437288329 0.7481598740015005 0.7995290208634283 1.0 14.404084297812599 -5.252707893666403 24.961535531090345 0.8225061184573934 0.5827083478203895 0.6442061664725219 0.07459614188436389 372.41258279391684 1064645.7252252712 0.018082363005387007 0.046291753313761105 5.588459479678869e-06 5.252707893666403 -0.23979777063700392 IRT(ph)LPLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IRTLPLAR 8 1 Q8TEH3;Q8TEH3-7;Q8TEH3-6 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 IRT(1)LPLAR 64.84100000000001 0.0385 1876500.0 7673.1 5697.5 6234.2 8631.5 9903.4 10749.0 11604.0 9359.7 9180.6 7415.5 True False 8972.004279366945 6263.11014653427 6382.846971335156 8147.905038700569 7962.899862151745 10185.303517466959 10504.785114315247 9114.01779242189 9314.848907011166 8759.871448934302 1.0242164319041978 0.714977403840352 0.7286461917328333 0.9301397955664997 0.9090201732492873 1.1627229436918358 1.199193980819573 1.0404282580574482 1.0633545208182686 1.0 13.09669398310203 -6.513470920033007 2.384254795780396 1.1010720645759409 0.8283737932890307 0.5587110018623802 0.10188957724312923 0.2111727376263442 2.4081111749570865 0.03677106558256567 0.03970867610893869 3.0656959487904003e-07 6.513470920033007 -0.27269827128691015 IRT(ph)LPLAR ddPTM_PC-9_Lapatinib_30min_R1 2 IRTLPLAR 8 1 Q8TEH3;Q8TEH3-7;Q8TEH3-6 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 IRT(1)LPLAR;IRT(1)LPLAR 84.198 0.010204000000000001 11579200.0 37115.0 26154.0 30546.0 25196.0 28592.0 28533.0 25755.0 22271.7 26569.0 23842.0 True False 36585.733293942605 26093.44201989697 28034.625790969825 27048.997891392057 26910.274774034817 27312.710103671656 27088.467879817155 23306.52448883822 23576.51943602661 27963.057932531938 1.3083595285685523 0.9331397904640509 1.0025593716756789 0.9673118711356503 0.962350928820545 0.9767426069627502 0.9687233758616474 0.8334755285016109 0.8431309441517814 1.0 14.77123451647414 -4.760509117200914 24.998033687401243 0.9429208201912288 1.3083599574878968 0.791552889516709 0.05623957180034296 10.95421269183433 294206.19273951126 0.015242051297286592 0.08975355861499294 1.7357648233507894e-05 4.760509117200914 0.365439137296668 IRT(ph)PSGEFLER ddPTM_PC-9_AZD4547_30min_R2 1 IRTPSGEFLER 11 1 B3KT28;B1ANM7;Q9UNN5-2;Q9UNN5 B3KT28 FAF1 FAS-associated factor 1 1 IRT(0.999)PS(0.001)GEFLER 106.55 0.0017444000000000003 7909200.0 7386.3 7211.3 8269.5 13274.0 11093.0 8941.4 7850.3 11952.0 8624.2 7927.1 True False 9734.989755415816 9542.211700342505 8159.8410268046855 10213.884381255639 9552.92842911802 8382.292844516862 8548.961491953783 10105.093029637157 9080.05760534675 7649.574641821452 1.2726184410559334 1.2474172940510577 1.066705197200577 1.335222526676803 1.248818251526121 1.0957854831155607 1.1175734458770086 1.3210006441915074 1.1870016347973935 1.0 12.901163812964636 -6.729988890350767 24.998088127871327 1.1626660271032299 1.2312050305826463 0.15745150928037577 0.09939650051796257 503.06908357200433 399858.1815445738 0.03333179625722722 0.03332864465464063 1.8621347711606375e-07 6.729988890350767 0.06853900347941644 IRT(ph)PSGEFLER ddPTM_PC-9_Lapatinib_30min_R1 1 IRTPSGEFLER 11 1 B3KT28;B1ANM7;Q9UNN5-2;Q9UNN5 B3KT28 FAF1 FAS-associated factor 1 1 IRT(0.826)PS(0.174)GEFLER 63.211999999999996 0.037327 4756800.0 11911.0 6487.2 9935.2 8558.6 9227.9 8603.5 7299.6 6734.0 9047.2 6099.8 True False 11741.14695579012 6472.179286972379 9118.366206981063 9188.027994652643 8685.133064749432 8235.548360738061 7677.5375707828925 7046.886223675626 8028.209064760439 7154.1423025274025 1.6411676563439657 0.904675782684096 1.2745575669860163 1.2842948331355826 1.2140006023756564 1.1511580301986195 1.0731597508300312 0.9850078354167088 1.122176317617312 1.0 12.804563099823403 -7.028808922939781 1.713662958688926 1.0378315543305825 1.249523122992832 0.2718864904389806 0.16920700190481233 0.5458960446237289 3.219152703787705 0.07777276109964705 0.05762450107398993 9.35817316244273e-08 7.028808922939781 0.21169156866224959 IRT(ph)SPTFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IRTSPTFR 8 1 P62750;H7BY10;K7EJV9;K7ERT8;A8MUS3 P62750 RPL23A 60S ribosomal protein L23a 1 IRT(0.979)S(0.021)PTFR;IRT(0.877)S(0.123)PTFR 73.84100000000001 0.020797 148593000.0 16385.0 16318.099999999999 13031.5 18869.2 24969.0 14046.9 14744.3 16780.300000000003 16826.5 16011.5 True False 19158.656881498675 17938.05312543411 13342.220382238966 17812.019898771792 20076.503691466256 13310.25583584581 13347.61316451209 16339.8349051975 17072.55572988948 18914.25820303574 1.0129213990757358 0.9483878739984131 0.7054054269015709 0.9417244761897646 1.061448113690442 0.7037154559785755 0.7056905442038323 0.8638898089365701 0.9026288816946219 1.0 14.207186576090733 -6.769634370978871 24.99968259057671 0.818584687893327 0.9225099859711305 0.13473934273534072 0.1198410879017616 382.6070608047646 1167176.1952826036 0.043714206654666035 0.039207039920654996 1.6996739921052913e-07 6.769634370978871 0.1039252980778036 IRTPS(ph)GEFLER ddPTM_PC-9_Lapatinib_30min_R1 2 IRTPSGEFLER 11 1 B3KT28;B1ANM7;Q9UNN5-2;Q9UNN5 B3KT28 FAF1 FAS-associated factor 1 1 IRT(0.088)PS(0.912)GEFLER;IRT(0.05)PS(0.95)GEFLER 101.45 0.0017587 8221600.0 24519.4 17394.4 21505.1 16647.5 20356.3 18443.2 14730.9 14843.2 21309.4 14161.2 True False 24169.74885969273 17354.124335508757 19737.03369008661 17871.81268443202 19158.982456025642 17654.427329199058 15493.593923152739 15532.86925976568 18909.310974069987 16608.94455138711 1.455224850977913 1.0448661732728473 1.1883376230814289 1.0760354235115706 1.1535340127573346 1.0629469726132978 0.9328463873918332 0.9352110973522662 1.1385016618946302 1.0 14.019672776819641 -2.240562343026731 1.1863698231267477 1.048656906964846 199.99965720037713 0.6477615291646266 0.08567832428028542 517.3550569583114 1.9224480586328159 0.026715121818594107 278711.2498174241 0.0057469531534018745 2.240562343026731 198.95100029341228 IRTS(ph)PTFR ddPTM_PC-9_Lapatinib_30min_R1 1 IRTSPTFR 8 1 P62750;H7BY10;K7EJV9;K7ERT8;A8MUS3 P62750 RPL23A 60S ribosomal protein L23a 1 IRT(0.241)S(0.758)PT(0.001)FR 57.148999999999994 0.039032 85088000.0 15320.0 7519.2 11503.0 8726.7 15199.0 13523.0 10875.0 10821.0 12230.0 5989.8 True False 15101.533990656075 7501.789754378273 10557.267742864075 9368.490629417809 14305.024702383715 12944.652813652678 11438.054288216335 11323.783164002669 10852.52861239059 7025.128949093191 2.1496450954975557 1.0678508264743822 1.5027863288156176 1.3335684935188414 2.0362650715799626 1.8426213821062434 1.6281628951014155 1.6118968414756787 1.5448155743520469 1.0 12.778308991491722 -8.95201779449456 1.7666712456246791 1.0000770460136807 1.631667084661596 0.291790871837303 0.3000136600793604 3.389000394552248 12.432125339399397 0.2897354375185568 0.08141720949884282 1.1168174871027981e-09 8.95201779449456 0.6315900386479152 IRVDVADQAQDKDRDDR ddPTM_PC-9_AZD4547_30min_R2 1 IRVDVADQAQDKDRDDR 17 3 E7EX17;P23588-2;P23588;F8VP89;F8W0K0;F8VSC7 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 50.023999999999994 0.026762 22797000.0 28787.0 21794.0 31761.0 48071.0 39095.0 42214.0 30363.0 31117.0 27568.0 49188.0 False True 37940.667193202986 28838.484295101396 31339.828387731275 36988.97363954647 33667.33407882168 39574.35190668522 33065.24817907503 26308.582647525054 29025.188198812542 47465.94309166199 0.7993239936249735 0.6075615992588853 0.6602592584584404 0.7792739642424605 0.7092945359540488 0.8337420333198218 0.6966099486366968 0.5542622970056714 0.6114950279774636 1.0 15.5346051276177 -5.717335566687581 24.999460826192667 0.7228312229021291 0.6808996188488041 0.02018832635557133 0.12402435102620718 725.3079543996103 411122.11331049213 0.03365031312245864 0.058283646584767736 1.9171868138532726e-06 5.717335566687581 -0.04193160405332497 IRVDVADQAQDKDRDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IRVDVADQAQDKDRDDR 17 3 E7EX17;P23588-2;P23588;F8VP89;F8W0K0;F8VSC7 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 ; 43.297 0.041147 28499000.0 54150.0 35863.0 43836.0 59071.0 76522.0 72609.0 67799.0 79207.0 63628.0 50292.0 False True 63316.52548874904 39423.241629689925 44881.21648895574 55761.44338076596 61528.06341777327 68801.2562191608 61376.58789774723 77127.90017675371 64558.4391276503 59409.54148874707 1.0657635777367849 0.6635843442278913 0.7554546856325565 0.9385940706397792 1.0356596242949876 1.158084282340281 1.0331099409237614 1.2982409600209206 1.0866678568774766 1.0 15.858407033690574 -6.221726154595039 2.047616508103669 1.127083115783108 0.8147468048605789 0.5041086568662543 0.12293554382806028 0.24247287649927757 1.9964691034171633 0.04058371022033011 0.05420899283432646 6.001693951889113e-07 6.221726154595039 -0.3123363109225291 IS(ph)APNVDFNLEGPK ddPTM_PC-9_AZD4547_30min_R2 4 ISAPNVDFNLEGPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 IS(1)APNVDFNLEGPK;IS(1)APNVDFNLEGPK;IS(1)APNVDFNLEGPK;IS(1)APNVDFNLEGPK 157.84 1.5159000000000002e-05 411565000.0 431043.0 523148.0 553035.0 705970.0 771938.0 808318.0 496208.0 526489.0 475054.0 616525.0 True False 568105.7077486308 692245.3602832755 545701.3945533502 543219.5236277723 664767.7333197959 757773.7476786852 540369.5507177322 445132.22256363975 500164.38459803694 594940.6474056044 0.9548947617312846 1.1635536474133916 0.917236697363048 0.9130650695941257 1.1173681546532264 1.273696377921323 0.9082747213090182 0.7481960167031051 0.8406962724418573 1.0 19.182386223589056 -7.508942174828213 24.84817148607648 0.8423147323911141 1.0546932900631767 0.35349316457168056 0.12098730437196657 636.7489011577737 1135296.080204761 0.05413844452934353 0.034813689296909325 3.0978317399336555e-08 7.508942174828213 0.2123785576720626 IS(ph)APNVDFNLEGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 ISAPNVDFNLEGPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 IS(1)APNVDFNLEGPK;IS(1)APNVDFNLEGPK;IS(1)APNVDFNLEGPK;IS(1)APNVDFNLEGPK;IS(1)APNVDFNLEGPK;IS(1)APNVDFNLEGPK 178.52 1.649e-05 300531200.0 351271.4 386456.0 412484.0 500816.0 627752.0 430907.0 578011.0 409963.0 435319.0 438596.0 True False 410734.71009360295 424820.7976812728 422319.1829142815 472756.9031873788 504748.50195543695 408309.4783515801 523257.6136427501 399201.90564170334 441684.7168323638 518109.9828759754 0.7927558311338776 0.81994327791782 0.8151149309458023 0.9124643778588355 0.9742111108410415 0.7880749104371548 1.0099354016268915 0.7704964560338609 0.8524921955385172 1.0 18.982898855953607 -11.501806067174066 0.017508468592829923 1.9203521398719205 3.244064005149184e-06 0.22519625021601875 0.07745171165407133 4024.937470643507 9.811935329223576 619.492951115864 465.07333940451394 3.1491542450289682e-12 11.501806067174066 -1.9203488958079153 IS(ph)APNVDFNLEGPK ddPTM_PC-9_Lapatinib_30min_R1 4 ISAPNVDFNLEGPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 IS(1)APNVDFNLEGPK;IS(1)APNVDFNLEGPK;IS(1)APNVDFNLEGPK;IS(1)APNVDFNLEGPK 177.07 1.5422e-05 302893000.0 826935.0 779462.0 761183.0 742071.0 939033.0 1065358.0 856534.0 819405.0 956975.0 612231.0 True False 815142.7552586925 777657.2036290041 698601.471991349 796645.37681629 883800.9251499109 1019795.1218107959 900881.1394669513 857477.5476850196 849190.3981064993 718054.3126034705 1.1352104443230842 1.0830061041057322 0.9729089565083304 1.10945002743298 1.2308274034947133 1.4202200361603496 1.2546142034863632 1.19416809095685 1.182626972920147 1.0 19.45373344600634 -6.179910087586121 4.070919702248462 1.2359969814384448 1.0632594225448053 0.28922249812922574 0.1042944991712443 0.2580730876790552 8.008121559801179 0.03194069617660979 0.041657142966511136 6.608302461824171e-07 6.179910087586121 -0.1727375588936395 IS(ph)ASSATR ddPTM_PC-9_AZD4547_30min_R2 2 ISASSATR 8 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;A0A1B0GV30;P49023-4;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 IS(0.949)AS(0.048)S(0.003)ATR;IS(0.919)AS(0.076)S(0.004)ATR 96.665 0.0060501999999999995 316160000.0 190916.0 187331.0 278790.0 385980.0 356000.0 276680.0 197793.0 299290.0 233557.0 247540.0 True False 251623.3167005091 247882.08229263287 275093.0624418503 296998.27433155465 306575.54500730365 259379.15586160196 215396.19382418707 253041.60750000918 245902.34620393434 238873.6999453118 1.0533738823408196 1.0377119052846064 1.151625576632466 1.243327643016163 1.2834210927259537 1.0858422501974254 0.901715818332032 1.059311291104634 1.0294241109851427 1.0 17.865888495886303 -7.0033631177893065 24.976522536513947 1.0013016343237817 1.1555154436363577 0.4645883578965587 0.07903895473653685 140.63543684002468 1044449.5305165171 0.031503825418712564 0.02722727161589315 9.922860415870343e-08 7.0033631177893065 0.154213809312576 IS(ph)ASSATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISASSATR 8 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;A0A1B0GV30;P49023-4;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 IS(0.992)AS(0.008)SATR 106.88 0.003819 91355000.0 71281.0 71195.0 85278.0 73519.0 103790.0 107510.0 135470.0 112330.0 87843.0 85281.0 True False 83347.46543607606 78262.76908863659 87311.35093861607 69399.96878181407 83453.0945627489 101871.98633946155 122637.30088213415 109381.45652347326 89127.53769237123 100741.77021597538 0.8273377096450805 0.7768651366841465 0.8666847004120883 0.6888897091348588 0.8283862233494396 1.0112189424611375 1.2173431201299918 1.0857607156294322 0.8847128405754141 1.0 16.620302461541883 -6.774429707284993 3.948311974925071 1.0609060284504443 0.7910775939448824 0.6534237155961341 0.08841605573957914 0.1308963983532459 4.507074398527337 0.03212890965520438 0.029726853513181533 1.681009983491e-07 6.774429707284993 -0.26982843450556193 IS(ph)ASSATR ddPTM_PC-9_Lapatinib_30min_R1 2 ISASSATR 8 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;A0A1B0GV30;P49023-4;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 IS(0.839)AS(0.042)S(0.119)ATR;IS(0.988)AS(0.009)S(0.003)ATR 102.06 0.0043946 247780000.0 188063.0 159379.0 130599.0 147466.0 198150.0 259220.0 216600.0 253980.0 268040.0 188049.0 True False 185381.18713346936 159009.9677177166 119861.65434671853 158311.1415721553 186495.2065778888 248133.76487133367 227814.48816806043 265780.8379995753 237850.51261366907 220553.0190904575 0.8405289027462245 0.7209602859823031 0.5434595946181926 0.717791768278745 0.8455799306079766 1.1250526784653272 1.0329239160159704 1.205065517106198 1.0784278247223502 1.0 17.75076598366322 -6.582664555124472 2.71474146643851 1.0998870949791588 0.6966547592866426 0.8156219688612931 0.08597380000527383 0.11113513679935307 1.6632963421514042 0.031337522350436645 0.032252712154578825 2.614179742065253e-07 6.582664555124472 -0.40323233569251626 IS(ph)DAELEAELEK ddPTM_PC-9_AZD4547_30min_R2 5 ISDAELEAELEK 12 0 Q8WUX9 Q8WUX9 CHMP7 Charged multivesicular body protein 7 1 IS(1)DAELEAELEK;IS(1)DAELEAELEK;IS(1)DAELEAELEK;IS(1)DAELEAELEK;IS(1)DAELEAELEK 188.13 0.00028475 23778000.0 44611.200000000004 54530.799999999996 64808.5 63962.1 65676.6 73975.59999999999 58781.5 71078.0 68521.9 71943.8 True False 58796.63362939584 72156.81469208567 63949.09694487835 49216.62604959407 56558.537750636664 69349.89403771695 64012.939625145715 60094.52830995224 72143.82774376866 69425.06945998855 0.8469078113530999 1.0393481094559291 0.921123989393109 0.7089172028550706 0.8146702364227781 0.9989171718104665 0.9220435805546874 0.8656027106258246 1.0391610452092814 1.0 16.083169095014973 -6.765847429952857 24.999971232636202 0.9540512358662819 0.8701272974905216 0.226874332874344 0.09003068440527574 228.54349147210795 1296160.6492113846 0.03395589590589297 0.030977627578766456 1.7145595359419558e-07 6.765847429952857 -0.08392393837576029 IS(ph)DAELEAELEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 ISDAELEAELEK 12 0 Q8WUX9 Q8WUX9 CHMP7 Charged multivesicular body protein 7 1 IS(1)DAELEAELEK;IS(1)DAELEAELEK;IS(1)DAELEAELEK;IS(1)DAELEAELEK;IS(1)DAELEAELEK;IS(1)DAELEAELEK;IS(1)DAELEAELEK 183.06 0.00030098 26457990.0 34379.0 40904.700000000004 44342.600000000006 50712.399999999994 54010.100000000006 42723.700000000004 57838.299999999996 46355.29999999999 43265.3 38060.4 True False 40198.68568379874 44965.448286255436 45399.895754246994 47871.14863981909 43427.20861974694 40483.19396122462 52359.437510970296 45138.52249250023 43897.973162594004 44960.44923403939 0.8940899472455552 1.0001111877728361 1.009774068713595 1.0647391086025007 0.9658980139119331 0.9004179150989208 1.164566600267178 1.0039606645728536 0.976368650902158 1.0 15.456368830243585 -7.216791465226804 24.99913603544734 1.0365546909620906 0.9793460879849607 0.17459631971070133 0.06688512172179843 916.3212884293434 513064.4981003564 0.026195470708147046 0.020290744213096148 6.070277355580977e-08 7.216791465226804 -0.05720860297712993 IS(ph)DAELEAELEK ddPTM_PC-9_Lapatinib_30min_R1 6 ISDAELEAELEK 12 0 Q8WUX9 Q8WUX9 CHMP7 Charged multivesicular body protein 7 1 IS(1)DAELEAELEK;IS(1)DAELEAELEK;IS(1)DAELEAELEK;IS(1)DAELEAELEK;IS(1)DAELEAELEK;IS(1)DAELEAELEK 177.93 8.5802e-05 21796500.0 45894.6 59254.3 60866.200000000004 56556.799999999996 70897.5 74350.29999999999 71301.3 70804.7 73683.3 56493.3 True False 45240.134587961125 59117.10030892335 55862.01598632645 60716.17573995407 66727.44843984801 71170.51098801442 74992.93243405978 74094.54484726531 65384.3108344529 66258.09163240937 0.6827865619635873 0.8922246151745021 0.8430972672174306 0.9163586551330052 1.007083765859762 1.07414067074039 1.1318305521099232 1.1182716408183242 0.986812466576851 1.0 16.015809031019877 -5.791645616565202 0.8668031061400573 1.077708635360454 0.7411901308799841 0.7764965121817948 0.06143615995165288 0.35606927419371104 0.493202708278966 0.02728935004130231 0.08622890683300033 1.6156764078117823e-06 5.791645616565202 -0.3365185044804698 IS(ph)DAELEAELEKLSLSEGGLVPSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISDAELEAELEKLSLSEGGLVPSSK 25 1 Q8WUX9 Q8WUX9 CHMP7 Charged multivesicular body protein 7 1 IS(0.973)DAELEAELEKLS(0.023)LS(0.004)EGGLVPSSK 70.572 0.00021600000000000002 3320900.0 5486.8 1660.8 1759.9 7018.7 7383.4 10902.0 6967.2 8745.7 9682.0 6187.2 True False 6415.606870760265 1825.6732481551746 1801.8626904579162 6625.464993932419 5936.675772180383 10330.279928125858 6307.216377840156 8516.134641835115 9823.580933455565 7308.890382151746 0.8777812411070124 0.24978801879604798 0.24653026605215628 0.906493961123258 0.8122540442907311 1.4133855329602865 0.8629512891919039 1.1651747661493803 1.3440591416509233 1.0 12.835436681034242 -6.122520651797657 1.9202767600878983 1.1335946404309991 0.44870950293105066 0.5713578977815472 0.24488155955866464 0.23249520653137795 1.6951653329457903 0.08032010414408078 0.1169310599083515 7.541875314761046e-07 6.122520651797657 -0.6848851374999485 IS(ph)DAELEAELEKLSLSEGGLVPSSK ddPTM_PC-9_Lapatinib_30min_R1 1 ISDAELEAELEKLSLSEGGLVPSSK 25 1 Q8WUX9 Q8WUX9 CHMP7 Charged multivesicular body protein 7 1 IS(0.832)DAELEAELEKLS(0.076)LS(0.09)EGGLVPS(0.001)SK 53.895 0.0038821 2691100.0 10457.0 3957.3 6014.6 5528.4 5867.0 7207.9 5128.6 4973.2 7323.5 5738.8 True False 10307.881262421062 3948.137114985788 5520.102805027406 5934.976978201768 5521.914594965802 6899.634919435564 5394.133813567471 5204.273027559197 6498.650310126127 6730.743933529663 1.5314624006228559 0.5865825760088527 0.8201326420291575 0.8817713222807769 0.8204018232602797 1.0250924693575936 0.8014171786711753 0.7732091844459797 0.9655173892075517 1.0 12.716550256050255 -4.747416809390424 24.999829260083185 0.8482624622113363 1.5314641209842133 0.7381510956876923 0.12125848697623469 363.2516945042199 647578.4308619668 0.029437655442247433 0.6026605237071649 1.788888164003145e-05 4.747416809390424 0.683201658772877 IS(ph)DAHLADTMIGK ddPTM_PC-9_AZD4547_30min_R2 2 ISDAHLADTMIGK 13 0 Q9Y657 Q9Y657 SPIN1 Spindlin-1 1 IS(0.997)DAHLADT(0.003)MIGK;IS(1)DAHLADTMIGK 111.12 0.00052962 23278000.0 132387.0 126245.0 157947.0 199771.0 192074.0 182315.0 141476.0 202904.0 153330.0 162906.0 True False 174483.31217933705 167051.22739446972 155852.51957926343 153716.88238118266 165407.8405385754 170914.81422910205 154067.08992467198 171549.8490700714 161434.71077060097 157202.71052472744 1.1099255960468406 1.0626485181894694 0.991411147168155 0.9778259030527563 1.052194583582306 1.0872256188115645 0.9800536479963413 1.0912652109970278 1.02692065697689 1.0 17.262266567522325 IS(ph)DAHLADTMIGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISDAHLADTMIGK 13 0 Q9Y657 Q9Y657 SPIN1 Spindlin-1 1 IS(1)DAHLADTMIGK 78.902 0.010039 5315200.0 29175.0 32940.0 40006.0 41083.0 44172.0 35380.0 41241.0 35510.0 31582.0 27211.0 True False 34113.751267483894 36210.065507123945 40959.894763599885 38781.25270288309 35516.81369135517 33524.61051706961 37334.35392101648 34577.90012595504 32043.827002726044 32144.13889784254 1.0612743858499676 1.1264904504738282 1.274257023769551 1.2064797512894652 1.1049234762278544 1.0429462933698226 1.1614669174890326 1.0757139967521685 0.9968793099284664 1.0 14.972268082767503 -7.830207060436226 0.7092321061372902 0.9906850217608324 1.1602634364103215 0.4239604174085366 0.06437044647937513 0.7097079847524803 0.7053799425636724 0.0658066219776905 0.03138454371119486 1.478403355424654e-08 7.830207060436226 0.16957841464948908 IS(ph)DAHLADTMIGK ddPTM_PC-9_Lapatinib_30min_R1 1 ISDAHLADTMIGK 13 0 Q9Y657 Q9Y657 SPIN1 Spindlin-1 1 IS(1)DAHLADTMIGK 118.76 0.00020985 6683600.0 45488.0 46806.0 51790.0 40267.0 41721.0 43686.0 41316.0 37048.0 43866.0 37643.0 True False 44839.33277852243 46697.62358275206 47532.026115181296 43228.36950677425 39267.052806641965 41817.65161703989 43455.140319259415 38769.385330373436 38925.34915054176 44149.54239385537 1.0156239532114169 1.057714781416428 1.0766142419133362 0.9791351656861267 0.8894101881361076 0.947181994413151 0.9842715906678887 0.8781378747828034 0.881670500756069 1.0 15.430110864092796 -5.961656560687672 4.508131009445008 0.9277605058793065 1.0496821482123448 0.6291931963759173 0.04110936739044372 0.12805338686423434 5.943327909761727 0.012113579916547743 0.017958528619914767 1.092303786909439e-06 5.961656560687672 0.12192164233303837 IS(ph)DSESEDPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISDSESEDPPR 11 0 Q96ST2-3;Q96ST2;B8ZZB6 Q96ST2-3 IWS1 Protein IWS1 homolog 1 IS(0.717)DS(0.195)ES(0.088)EDPPR 88.155 0.027819999999999998 0.0 13845.0 25849.0 35962.0 23607.0 30946.0 21045.0 23121.0 13949.0 19443.0 17239.0 True False 16188.68504878543 28415.11788991037 36819.47046664449 22284.37632492664 24882.353447719743 19941.363152394857 20930.811498455947 13582.853530187185 19727.31709245781 20364.294236151083 0.7949543873731194 1.3953401753284094 1.8080405851375818 1.0942866993822449 1.2218618116186966 0.97923173379584 1.0278191453990668 0.666993580660146 0.9687208829185694 1.0 14.31375419538115 -6.746904998328378 1.4683682991090186 0.8825001260219916 1.3218630694625215 0.3011491361186527 0.2550504327850855 0.4683752451825804 2.104292044918798 0.11819899110440744 0.10837408714945765 1.7909975908949335e-07 6.746904998328378 0.43936294344052995 IS(ph)EDETERNGDDGTHDK ddPTM_PC-9_Lapatinib_30min_R1 1 ISEDETERNGDDGTHDK 17 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-3;Q9UKV3-2;G3V3B0;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 IS(0.994)EDET(0.006)ERNGDDGTHDK 55.126999999999995 0.025135 16992000.0 18885.0 22793.0 24936.0 23761.0 24619.0 23952.0 23815.0 25338.0 23863.0 26118.0 True False 18615.69643691514 22740.22420889776 22885.858335743596 25508.463204372383 23170.958822816294 22927.628794839067 25048.024172310063 26515.295980916704 21175.29765146989 30632.461499952562 0.6077114121874916 0.7423570648716223 0.7471113066045652 0.8327265245860795 0.7564184426658686 0.7484749077338945 0.8176954428670008 0.8655946888550816 0.6912698691061011 1.0 14.90277368024705 -14.522878745280336 0.09267061636628338 1.6967533327269961 0.5917563217993519 0.5741474997155905 0.06575265716432196 156.472723912178 0.998354807444865 21.851907310604233 1.4109253250833476 3.0000000000000132e-15 14.522878745280336 -1.1049970109276441 IS(ph)FVEEDVHPK ddPTM_PC-9_AZD4547_30min_R2 5 ISFVEEDVHPK 11 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 IS(1)FVEEDVHPK;IS(1)FVEEDVHPK;IS(1)FVEEDVHPK;IS(1)FVEEDVHPK;IS(1)FVEEDVHPK 116.51 0.00071047 22915550.0 89931.3 127535.4 124325.1 116260.7 102001.2 124780.9 118390.3 131379.5 103825.4 100384.7 True False 118527.58271275563 168758.72395932244 122676.46794142279 89458.59182490938 87840.09404887346 116978.33059726364 128926.80734759921 111077.81707557007 109313.39868024485 96870.26220772475 1.2235703714581652 1.7421107377354148 1.2663996684385992 0.9234886928774687 0.9067808019401522 1.2075773093957354 1.3309224565856308 1.1466658037673028 1.1284515617996111 1.0 16.56376622630428 -5.517292115802925 24.402362940790287 1.1043651472443765 1.4881942655431348 0.46371968920003837 0.16777896028328837 147.7088778748899 645189.7011912689 0.046315757882268715 0.08364038253562225 3.0388403487734324e-06 5.517292115802925 0.3838291182987583 IS(ph)FVEEDVHPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ISFVEEDVHPK 11 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 IS(1)FVEEDVHPK;IS(1)FVEEDVHPK;IS(1)FVEEDVHPK 113.69 0.00086791 9180600.0 69743.0 77043.0 68790.0 77851.0 103849.0 80664.0 124903.0 91455.0 82506.0 79482.0 True False 81549.11241296068 84691.31988055121 70430.21448752789 73489.26086634732 83500.53393628419 76433.83783914357 113071.2836205891 89054.40315458213 83712.49416398311 93891.45742083434 0.8685466671099418 0.9020130500366305 0.7501237750719967 0.7827044428222945 0.8893304697787722 0.8140659431513206 1.2042765841176388 0.9484824881930219 0.891587972575314 1.0 16.518706281866862 -7.150372030698037 23.318264319540784 1.0071950335798185 0.8338382526831687 0.5005069415759429 0.08640184473908162 12.81853518984021 2673.831006052235 0.0335620277412666 0.02599705134037893 7.073395948085336e-08 7.150372030698037 -0.17335678089664985 IS(ph)FVEEDVHPK ddPTM_PC-9_Lapatinib_30min_R1 4 ISFVEEDVHPK 11 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 IS(1)FVEEDVHPK;IS(1)FVEEDVHPK;IS(1)FVEEDVHPK;IS(1)FVEEDVHPK 131.79 7.9783e-05 17337000.0 72406.0 105012.0 94881.0 74453.0 96904.0 141133.0 185477.0 154418.0 132147.0 101234.0 True False 71373.47716236579 104768.851165918 87080.25043125139 79928.52198792713 91204.2972405943 135097.0705870917 195080.09151406895 161592.82401062423 117263.21329039906 118732.16201417433 0.6011301062120402 0.882396558679784 0.7334175420881807 0.6731834124134386 0.7681515748842025 1.1378304605534237 1.6430265246141154 1.3609861158877337 0.9876280470358156 1.0 16.857351257718264 -6.828026654451199 3.8522467558810107 1.2902993543695866 0.7333796817778063 0.634168627802354 0.18769501830184818 0.1386832957298868 4.0911926927772475 0.06861768803459999 0.06149405672230701 1.4858444470604468e-07 6.828026654451199 -0.5569196725917803 IS(ph)HIPDY(ph)AFQNLT(ph)SLVVLDLNY(ph)NK ddPTM_PC-9_Lapatinib_30min_R1 1 ISHIPDYAFQNLTSLVVLDLNYNK 24 0 Q5T508 Q5T508 LGR6 4 IS(0.983)HIPDY(0.983)AFQNLT(0.982)S(0.057)LVVLDLNY(0.995)NK 43.799 0.043648 0.0 3097.0 5696.5 4472.9 4175.1 5960.5 6282.4 3094.1 4210.7 6061.7 4703.4 True False 3052.836212079756 5683.310104241917 4105.155427893309 4482.150781725314 5609.915108793876 6013.716396989685 3254.2973584524266 4406.3444939160945 5378.967513469174 5516.376423113445 0.5534133238784191 1.0302614738959845 0.7441760882547529 0.8125172102007475 1.0169565451132936 1.090157004477142 0.5899338821072874 0.7987751661495849 0.9750907300182541 1.0 12.429505190612964 -4.744389877012554 24.75189514037922 0.8820662448767621 0.5534122155859313 0.3180948592393523 0.14904711981519675 1228.6492242144384 1783603.5257198866 0.037823917714542715 1.0693677968357336 1.8013998530809963e-05 4.744389877012554 -0.32865402929083076 IS(ph)IPDVDLDLKGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISIPDVDLDLKGPK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 IS(1)IPDVDLDLKGPK 79.089 0.006221 1383600.0 15785.0 14255.0 13236.0 12479.0 15569.0 12228.0 11155.0 13855.0 11685.0 10867.0 True False 18457.08873203885 15670.142191987014 13551.596437809527 11779.84208746387 12518.366213001638 11586.742153836265 10098.31764479374 13491.320930585951 11855.871019151846 12837.101076875328 1.4377925842842612 1.2206916575748639 1.0556586223521514 0.9176403626426222 0.9751708067136858 0.9025980308520394 0.7866509412303986 1.0509632081100562 0.9235629561653087 1.0 13.648031823893815 -4.954661223225607 1.2233829054449448 0.9288611180414497 1.577904150958642 0.8532461791627418 0.0671196647672203 0.38963664544189075 0.6219826818297347 0.020877394711433947 0.29755712622369557 1.1100403783286775e-05 4.954661223225607 0.6490430329171923 IS(ph)IPDVDLDLKGPK ddPTM_PC-9_Lapatinib_30min_R1 1 ISIPDVDLDLKGPK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 IS(1)IPDVDLDLKGPK 75.102 0.023286 0.0 5669.0 4909.6 4792.4 4396.0 4390.1 4090.7 4018.0 4682.9 4954.5 4007.7 True False 5588.159020432722 4898.232122844924 4398.387371198974 4719.2965046261115 4131.882949268684 3915.75029688745 4226.032379775007 4900.4846297669465 4396.47203680206 4700.425605075421 1.1888623477837295 1.0420826823758076 0.935742364787071 1.0040147214606086 0.8790444305313891 0.8330629236338312 0.8990744104559012 1.0425618957729075 0.9353348837294311 1.0 12.198575677735846 -4.650801475618037 1.3356329151592212 0.9334603096280215 1.3632215447454021 0.6244071978081587 0.0595738756854516 1.2131708138840736 1.550212580933642 0.018755116193322367 0.7711535730915847 2.2345934651594503e-05 4.650801475618037 0.4297612351173806 IS(ph)LGAPK ddPTM_PC-9_AZD4547_30min_R2 1 ISLGAPK 7 0 P56715 P56715 RP1 Oxygen-regulated protein 1 1 IS(1)LGAPK 75.043 0.033296 3603800.0 40444.0 45627.0 39552.0 39508.0 36965.0 42005.0 36236.0 48109.0 46918.0 39674.0 True False 53304.35071254043 60375.035465384586 39027.51463718229 30400.04099251528 31833.047812345387 39378.42070972453 39460.93380156648 40674.859484840534 49397.98969500458 38285.025335825754 1.3923028715527617 1.5769882593988462 1.019393726263562 0.7940452102579129 0.8314751664159711 1.0285593483172026 1.030714579797871 1.062422164489949 1.2902692178390622 1.0 15.224492591589438 -5.270287862211148 23.52630444301349 0.9970661930167795 1.4846455707283983 0.6709248581022653 0.13362740880143897 151.22683089509962 402083.7011552925 0.037727908826052974 0.08067156505082179 5.366759550125985e-06 5.270287862211148 0.48757937771161886 IS(ph)MAMQEGAASLSRPK ddPTM_PC-9_AZD4547_30min_R2 1 ISMAMQEGAASLSRPK 16 1 A7KAX9;A7KAX9-2;G3V174 A7KAX9 ARHGAP32 Rho GTPase-activating protein 32 1 IS(1)MAMQEGAASLSRPK 113.52 0.0058931999999999995 0.0 14162.0 11413.0 15158.0 20364.0 18669.0 17376.0 16504.0 17408.0 14434.0 17434.0 True False 18665.221412100622 15102.029056620739 14956.995015938735 15669.394420663688 16077.131600397033 16289.475973150185 17972.824027515544 14717.993596044473 15196.951772404977 16823.640966496605 1.1094638461003434 0.8976671034941625 0.8890462561418663 0.9313913945184911 0.955627359880884 0.9682491444979014 1.0683076311071709 0.8748399722363656 0.9033093254111227 1.0 14.03820234648987 -9.052305937923206 0.0017657360021448747 0.5870164469215815 1.319547390447512 0.0 0.07494360617460047 3348766.66473389 2454.594876901635 511434.84691859316 506860.0632164937 8.865312767423057e-10 9.052305937923206 0.7325309435259304 IS(ph)MAMQEGAASLSRPK ddPTM_PC-9_Lapatinib_30min_R1 1 ISMAMQEGAASLSRPK 16 1 A7KAX9;A7KAX9-2;G3V174 A7KAX9 ARHGAP32 Rho GTPase-activating protein 32 1 IS(1)MAMQEGAASLSRPK 115.1 0.004646 0.0 4384.4 4665.5 6697.5 5508.3 8893.7 7841.6 10434.0 10131.0 10472.0 7758.1 True False 4321.877651999512 4654.697321397463 6146.857403097637 5913.398757150138 8370.590051686953 7506.233047662414 10974.221466045901 10601.723245033827 9292.53308495129 9099.07724798155 0.4749797736861982 0.5115570727163588 0.6755473368973975 0.6498899389453924 0.9199383435879505 0.8249444249225957 1.2060807010381536 1.165142679427808 1.0212610390809305 1.0 13.151504531373334 -6.315158473820819 0.8376041041643794 1.1098860977242218 0.4862431754211453 0.8597482708553195 0.09240890630184236 0.21924649676826136 0.3335918321282226 0.05025479218215699 0.07890857968699616 4.839957255801022e-07 6.315158473820819 -0.6236429223030764 down IS(ph)MPDLDLHLK ddPTM_PC-9_AZD4547_30min_R2 1 ISMPDLDLHLK 11 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 IS(1)MPDLDLHLK 80.96 0.016635 0.0 5661.7 5280.5 9011.3 12120.0 10160.0 9354.5 8027.4 9584.2 8131.1 9436.9 True False 7462.002829324259 6987.3183591944035 8891.804274121178 9325.921252133372 8749.459374365733 8769.561636212788 8741.82304886563 8103.182113006059 8560.893346030345 9106.51700336881 0.8194134844928979 0.7672876860175583 0.9764220800149823 1.0240931026300613 0.9607909776184475 0.9629984365008739 0.9599524215055804 0.8898223228494953 0.9400842652425049 1.0 13.152683652323951 -5.2638700408492936 24.99804422761344 0.962148149193179 0.7933505761044749 0.7881068333731267 0.035436512948362975 91.5390673219462 941441.5977027678 0.009987290360148796 0.022505902046785327 5.446656152883474e-06 5.2638700408492936 -0.16879757308870413 IS(ph)MSEVDLNVAAPK ddPTM_PC-9_AZD4547_30min_R2 5 ISMSEVDLNVAAPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 IS(0.993)MS(0.007)EVDLNVAAPK;IS(0.733)MS(0.267)EVDLNVAAPK;IS(0.771)MS(0.229)EVDLNVAAPK;IS(0.986)MS(0.014)EVDLNVAAPK;IS(0.931)MS(0.069)EVDLNVAAPK 182.57 1.5708e-05 57417900.0 137124.9 148820.0 185641.0 208224.0 239481.0 231103.0 168723.0 204562.0 171652.0 196843.0 True False 180727.7658248942 196923.15466628378 183179.27904432543 160221.17382873085 206233.19689296008 216652.09287654964 183739.02014023945 172951.64326712163 180725.17428549647 189951.58648434622 0.9514412023075566 1.0367018160309605 0.9643471920115873 0.8434842624593429 1.085714527106388 1.1405647980434415 0.9672939486366504 0.9105038103031293 0.9514275591501307 1.0 17.535272235945094 -7.512842453876386 24.731515904214415 0.9463591714118643 1.0043694938167642 0.07785849223959163 0.077902140351226 1115.8836298867634 2749790.741583282 0.037382579818649044 0.023281667322282058 3.07013551906821e-08 7.512842453876386 0.058010322404899894 IS(ph)MSEVDLNVAAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ISMSEVDLNVAAPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 IS(1)MSEVDLNVAAPK;IS(0.999)MS(0.001)EVDLNVAAPK 160.79 0.00026524 10353600.0 61112.0 56760.0 59017.0 64054.0 90681.0 65031.0 85024.0 67622.0 63516.0 62699.0 True False 71457.0545829813 62394.75768622818 60424.18910321889 60465.26204586992 72912.70900900521 61620.6598794673 76969.91119954656 65846.99415143133 64444.80133953354 74065.83237498919 0.9647775808580689 0.8424229592172634 0.8158173231254084 0.8163718695516617 0.9844311023179243 0.8319714759632618 1.0392094266875214 0.8890333375051189 0.870101628146901 1.0 16.176520539741787 -6.2543080563182025 24.980160634869247 0.9302227579614238 0.855457821033395 0.2140122939324811 0.0706185085185115 908.7218634255956 3183138.588335665 0.02066916774261158 0.026090510040310575 5.56790662795826e-07 6.2543080563182025 -0.07476493692802888 IS(ph)MSEVDLNVAAPK ddPTM_PC-9_Lapatinib_30min_R1 6 ISMSEVDLNVAAPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 IS(0.967)MS(0.033)EVDLNVAAPK;IS(0.992)MS(0.008)EVDLNVAAPK;IS(0.831)MS(0.169)EVDLNVAAPK;IS(0.831)MS(0.169)EVDLNVAAPK;IS(0.999)MS(0.001)EVDLNVAAPK;IS(0.878)MS(0.122)EVDLNVAAPK 218.12 1.4957e-15 62753100.0 332150.0 386786.0 381185.0 326281.0 443824.0 499599.0 436755.0 383054.0 493506.0 377714.0 True False 327413.4800911498 385890.42078106065 349845.4407166509 350276.79318150936 417719.14491155616 478232.3153921512 459368.03684137267 400852.08724737825 437922.1574314332 443001.3616277305 0.7390800761607744 0.8710817938869855 0.789716400489618 0.7906901050924064 0.9429297087862681 1.079527867894064 1.0369449772197217 0.9048552035472709 0.9885345630143559 1.0 18.756951607552445 -6.3739701804460065 3.916919573611736 0.9992140724949459 0.8022888005740504 0.7785177372200532 0.05144114863283378 0.11827606113068947 3.1915286297024386 0.01725922654390055 0.019758757961106686 4.226976365599232e-07 6.3739701804460065 -0.19692527192089548 IS(ph)PDLNIK ddPTM_PC-9_AZD4547_30min_R2 1 ISPDLNIK 8 0 E9PEI0;Q69YH5 E9PEI0 CDCA2 Cell division cycle-associated protein 2 1 IS(1)PDLNIK 77.744 0.023109 7558400.0 79384.0 82851.0 72830.0 66623.0 73740.0 89791.0 77776.0 91328.0 67617.0 78887.0 True False 104626.4607102241 109630.96551039032 71864.22661372335 51264.096665089215 63502.4738450521 84176.35457557153 84697.91332792347 77215.35610865986 71191.0965771585 76125.19014133392 1.3743999918551895 1.4401404490005165 0.9440268914967612 0.6734183070007755 0.8341847649530135 1.1057621586138549 1.1126134880014544 1.0143206994334193 0.9351844828891095 1.0 16.21608630605764 -5.263502320656115 24.828509565233446 0.9499582665343025 1.407270253081043 0.6885859884910119 0.12233988921895342 95.28647987825141 1146837.599328776 0.03645329193940483 0.08249790305005922 5.451269827906385e-06 5.263502320656115 0.45731198654674055 IS(ph)PDLNIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISPDLNIK 8 0 E9PEI0;Q69YH5 E9PEI0 CDCA2 Cell division cycle-associated protein 2 1 IS(1)PDLNIK 75.509 0.026271 1718300.0 22960.0 29054.0 22686.0 21374.0 22952.0 20158.0 21216.0 17996.0 19760.0 17474.0 True False 26846.67451932922 31938.289108803252 23226.92027713411 20176.48407544295 18454.720362310592 19100.878993869115 19206.26688946159 17523.62406833812 20048.952617752722 20641.897875892104 1.3005913836384075 1.5472554559096199 1.125231818158595 0.977452954992442 0.8940418402061789 0.9253450970793359 0.9304506303120895 0.8489347333126839 0.9712746733994897 1.0 14.333288001970573 -5.514166051829771 2.8370334886279767 0.9260131556901542 1.4233796745333378 0.8774391276812746 0.0721058737839943 0.07359029764185421 1.1859901866127605 0.018901982000271066 0.04182546754915231 3.0607929204492867e-06 5.514166051829771 0.4973665188431836 IS(ph)PDLNIK ddPTM_PC-9_Lapatinib_30min_R1 2 ISPDLNIK 8 0 E9PEI0;Q69YH5 E9PEI0 CDCA2 Cell division cycle-associated protein 2 1 IS(1)PDLNIK;IS(1)PDLNIK 94.465 0.006725 17148400.0 63885.0 81688.0 79880.0 77903.0 88960.0 78470.0 79895.0 84837.0 77051.0 69757.0 True False 62973.98818492586 81498.85645489582 73312.5747457169 83632.24649678983 83727.54770208932 75114.02102250436 84031.57217076267 88778.83673269508 68372.70499699983 81814.40450464009 0.7697176134962188 0.9961431235531836 0.8960839498814539 1.0222190945855585 1.0233839408724257 0.9181026431384008 1.02709996704794 1.085124768312162 0.8357049765377451 1.0 16.32006725056356 -4.758896217930548 24.979262635105577 0.9807375644666142 0.7697173322821718 0.44198756712188647 0.07022662579140979 61.86081386904797 607478.7813887515 0.016763395946590598 0.11061614893918563 1.7422231575720395e-05 4.758896217930548 -0.21102023218444244 IS(ph)PGATLPESR ddPTM_PC-9_AZD4547_30min_R2 4 ISPGATLPESR 11 0 Q8NC74 Q8NC74 RBBP8NL RBBP8 N-terminal-like protein 1 IS(0.987)PGAT(0.013)LPESR;IS(1)PGATLPESR;IS(1)PGATLPESR;IS(0.999)PGAT(0.001)LPESR 147.58 0.00014423 70376000.0 101794.0 115708.0 166066.0 205694.0 170887.0 169825.0 134421.0 170549.0 137069.0 142057.0 True False 134162.37455326723 153108.34820673527 163863.856334403 158274.42624062073 147162.289774334 159205.8159035584 146384.2085920183 144194.57087613703 144314.18750809037 137083.62766878583 0.9786899926329877 1.1168974064260067 1.1953568717215606 1.1545830011373421 1.0735219973161179 1.1613773184367648 1.0678460373524985 1.051873030560092 1.052745612019946 1.0 17.064696750211013 -7.907147446022695 1.1630252764700981 1.014240821812432 1.1174827254960538 0.27783848567700975 0.056981729702396955 0.6456042261948219 1.5754832921674513 0.05262579115067834 0.01918025538133371 1.238376077787345e-08 7.907147446022695 0.10324190368362185 IS(ph)PGATLPESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ISPGATLPESR 11 0 Q8NC74 Q8NC74 RBBP8NL RBBP8 N-terminal-like protein 1 IS(0.658)PGAT(0.341)LPES(0.001)R;IS(0.998)PGAT(0.002)LPESR;IS(1)PGATLPESR;IS(0.997)PGAT(0.003)LPESR;IS(1)PGATLPESR 132.86 8.6964e-05 47620200.0 128125.6 149640.9 147002.0 165509.8 156967.0 152161.0 149540.0 128587.3 128757.7 114530.4 True False 149814.73348404933 164496.25960974421 150507.0851881892 156236.82249601185 126210.44314703759 144181.4092958686 135374.4886241559 125212.01962450608 130640.53777686328 135293.85489785258 1.107328441466614 1.215844280096384 1.112445833565927 1.1547961480879623 0.9328616088463663 1.065690747038926 1.0005959895692542 0.925481942391557 0.9656058501363378 1.0 17.04573678744137 -6.251658642383181 24.808485597159983 0.9831238546751571 1.1499667435803578 0.757347672718012 0.04599147301234786 307.87309639222053 780908.6631895932 0.013793438062718953 0.017574716811912774 5.601977467017059e-07 6.251658642383181 0.16684288890520071 IS(ph)PGATLPESR ddPTM_PC-9_Lapatinib_30min_R1 3 ISPGATLPESR 11 0 Q8NC74 Q8NC74 RBBP8NL RBBP8 N-terminal-like protein 1 IS(1)PGATLPESR;IS(1)PGATLPESR;IS(0.999)PGAT(0.001)LPESR 160.86 0.00096748 47693000.0 129504.0 126124.0 148472.0 125601.0 140215.0 148273.0 120637.0 117685.0 146569.0 108994.0 True False 127657.24921187523 125831.96762703557 136265.2052784939 134838.11653265342 131967.82937329644 141931.7094312448 126882.99357862562 123153.0747302146 130060.85578000627 127833.46767462433 0.9986214997844098 0.9843429104756573 1.0659587646118693 1.0547951094924382 1.0323417785176205 1.1102859995357774 0.9925647476103991 0.9633867951049973 1.0174241389668888 1.0 16.96390606758529 -7.472965339083671 24.99575767178871 0.9898382406482229 1.0408053248061424 0.3066464989144223 0.0350128645264402 453.8766294372209 227293.67891519208 0.015358837323155359 0.010354741235894607 3.365384273377504e-08 7.472965339083671 0.05096708415791951 IS(ph)PPIKEEETKGDSVEK ddPTM_PC-9_AZD4547_30min_R2 1 ISPPIKEEETKGDSVEK 17 2 Q6PJT7;Q6PJT7-2;Q6PJT7-9;Q6PJT7-5;H0YJA2;Q6PJT7-11;Q6PJT7-3;Q6PJT7-4;G3V256;Q6PJT7-10;G3V5I6;A0A087WTC9 Q6PJT7 ZC3H14 Zinc finger CCCH domain-containing protein 14 1 IS(0.999)PPIKEEET(0.001)KGDSVEK 72.21 0.034654000000000004 16938000.0 53095.0 61607.0 48495.0 52859.0 56585.0 61733.0 65096.0 55304.0 63922.0 57302.0 True False 69978.10555539351 81520.25795945256 47851.92461392987 40673.17421340906 48729.149478197294 57872.82575106355 70889.41789233823 46758.03755949239 67300.78642065062 55295.87442137139 1.2655212760022394 1.4742556983228692 0.8653796529065377 0.7355553129238377 0.8812438538699352 1.0466029582976664 1.282001932949632 0.8455972176727312 1.2171032129413155 1.0 15.754884225762455 -5.260618527099851 24.999498135727904 0.9789804861313798 1.369888505419264 0.46389408615939143 0.1657795638541711 62.915676953723086 1916048.6136315628 0.044948105112560505 0.10561685748740535 5.487587686201551e-06 5.260618527099851 0.3909080192878842 IS(ph)PSSLSNNYNNMNNR ddPTM_PC-9_AZD4547_30min_R2 2 ISPSSLSNNYNNMNNR 16 0 Q9Y4E8 Q9Y4E8 USP15 Ubiquitin carboxyl-terminal hydrolase 15 1 IS(0.934)PS(0.066)SLSNNYNNMNNR;IS(0.965)PS(0.018)S(0.006)LS(0.011)NNY(0.001)NNMNNR 123.63 3.3698e-05 15914600.0 31792.0 26550.0 38979.0 49509.0 42729.0 36830.0 35715.0 40872.0 29747.0 32740.0 True False 41901.19468532008 35131.768286452316 38462.11299157383 38095.46495642502 36796.815906227705 34527.01427780393 38893.56581087721 34556.17154512465 31319.365690295894 31593.78256528043 1.3262481185575683 1.1119836067068432 1.217395002073644 1.205789932804359 1.1646853563734112 1.0928420554412164 1.2310512592315799 1.0937649353547079 0.9913142127120257 1.0 14.947353053623281 -8.034324819587873 3.203943749240906 0.9978251896029169 1.1861785961866704 0.6195239576661808 0.06187897209396468 0.16878598911844372 3.3863667152847974 0.04473286866617962 0.0159397284493475 9.24006827865668e-09 8.034324819587873 0.18835340658375355 IS(ph)PSSLSNNYNNMNNR ddPTM_PC-9_Lapatinib_30min_R1 2 ISPSSLSNNYNNMNNR 16 0 Q9Y4E8 Q9Y4E8 USP15 Ubiquitin carboxyl-terminal hydrolase 15 1 IS(0.347)PS(0.241)S(0.241)LS(0.17)NNY(0.001)NNMNNR;IS(0.722)PS(0.142)S(0.038)LS(0.083)NNY(0.014)NNMNNR 80.488 0.007066199999999999 11210900.0 42967.0 40814.0 53666.0 40977.0 40219.0 47330.0 40006.0 31144.0 43406.0 33828.0 True False 42354.28270081721 40719.49769060467 49253.788636750745 43990.5852752648 37853.39749359634 45305.806231618764 42077.31492913863 32591.06393676176 38517.15919455652 39675.124727023314 1.0675273988986123 1.0263231173378018 1.2414274429036203 1.1087699302253777 0.9540838939773725 1.1419196925866324 1.060546506624569 0.8214483044728402 0.9708138149423867 1.0 15.27594713802957 -7.617933140246446 7.396044253597533 0.9230772970751223 1.0896569763153288 0.430031301352494 0.08221296684468427 0.20964978572149115 14.111772194972398 0.03925705180945881 0.022508517537846592 2.4102764628421554e-08 7.617933140246446 0.16657967924020645 IS(ph)SKSPGHMVILDQTK ddPTM_PC-9_AZD4547_30min_R2 2 ISSKSPGHMVILDQTK 16 1 Q9NWH9;Q9NWH9-3 Q9NWH9 SLTM SAFB-like transcription modulator 1 IS(0.488)S(0.411)KS(0.1)PGHMVILDQTK;IS(0.716)S(0.235)KS(0.049)PGHMVILDQTK 72.676 0.0066818 24062000.0 78784.0 60959.0 162746.0 395941.0 294166.0 184321.0 114944.0 180474.0 131489.0 216299.0 True False 103835.67319099933 80662.80463178323 160587.88170365273 304662.9196774705 253326.12857477044 172795.37873198773 125173.79332396667 152585.89017994783 138439.2400998861 208726.43784629117 0.49747254953617925 0.38645226481172623 0.7693701064448372 1.4596278402538936 1.2136753311591657 0.8278557355500719 0.5997026280693117 0.7310328856966075 0.6632568520229074 1.0 17.67125382210306 -5.396041648191511 4.778779148834587 0.9236034862424944 0.4487287872733367 0.3748754582683461 0.24648264504846623 0.26036926506548597 8.88587613729779 0.07491777554444633 0.1619164576166986 4.017522815583674e-06 5.396041648191511 -0.47487469896915774 IS(ph)TPLTGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISTPLTGVR 9 0 Q08999;F5H837;Q08999-2 Q08999 RBL2 Retinoblastoma-like protein 2 1 IS(0.951)T(0.049)PLTGVR 125.68 0.0014187000000000002 3302600.0 28177.0 29299.0 36337.0 42144.0 42540.0 44424.0 39541.0 45897.0 40432.0 34793.0 True False 32946.80957888239 32207.611089654656 37203.4118888399 39782.80831269149 34204.59237594513 42094.3272360175 35795.39022795065 44692.25238189125 41023.241510170985 41100.69547876354 0.8016119726223561 0.7836269122573879 0.9051771863097222 0.9679351614195193 0.8322144425419375 1.0241755460748192 0.870919331436761 1.0873843340432876 0.9981155071054071 1.0 15.326875185993488 -4.1399770885943115 0.30100551912965257 1.0266113675389419 0.46694731833249065 0.5447800519450636 0.06614528996019368 8.50535877445897 0.4663079323090734 0.07084940708633007 1.8736916994800938 7.244741790362928e-05 4.1399770885943115 -0.5596640492064513 IS(ph)TYGLPAGGIQPHPQTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ISTYGLPAGGIQPHPQTK 18 0 Q9Y5K6 Q9Y5K6 CD2AP CD2-associated protein 1 IS(0.824)T(0.175)Y(0.001)GLPAGGIQPHPQTK;IS(0.491)T(0.488)Y(0.022)GLPAGGIQPHPQTK 77.045 0.0028959 15134600.0 118632.0 116673.0 107796.0 111776.0 162549.0 133989.0 142385.0 163167.0 116241.0 111531.0 True False 138714.0545111961 128255.52437500516 110366.26545860671 105513.5531026816 130698.69031776003 126962.38096584605 128897.26202187003 158884.03913972716 117940.80471863326 131750.68742108977 1.0528526053746545 0.973471386643216 0.8376902437394039 0.8008577045632302 0.9920152439131689 0.963656307614246 0.9783422352089908 1.2059446690544862 0.8951817028603533 1.0 17.007450963710383 -7.057336467186581 1.7880819743001755 1.0384025950509594 0.9199973409110344 0.15019562270709752 0.09918067080299324 0.5957708977116447 3.8010969074756216 0.04861240398022704 0.03548454554699444 8.763216328643174e-08 7.057336467186581 -0.11840525413992509 IS(ph)YTPPES(ph)PVPSYASSTPLHVPVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ISYTPPESPVPSYASSTPLHVPVPR 25 0 P41212 P41212 ETV6 Transcription factor ETV6 2 IS(0.717)Y(0.183)T(0.19)PPES(0.904)PVPS(0.004)Y(0.001)ASSTPLHVPVPR;IS(0.516)Y(0.322)T(0.366)PPES(0.786)PVPS(0.004)Y(0.004)AS(0.001)STPLHVPVPR;IS(0.376)Y(0.314)T(0.376)PPES(0.935)PVPSYASSTPLHVPVPR;IS(0.388)Y(0.31)T(0.347)PPES(0.946)PVPS(0.004)Y(0.004)ASSTPLHVPVPR 82.56 0.00018528 4149400.0 10326.15 9076.86 15260.399999999998 18678.399999999998 24152.600000000002 17299.5 19810.800000000003 15866.4 13520.400000000001 12732.9 True False 12074.163244240917 9977.950673922078 15624.265811389274 17631.90980418985 19420.071410889817 16392.28376597077 17934.17760622859 15449.923811840414 13718.110271916195 15041.273976419063 0.8027354107883528 0.6633713799485998 1.0387594718295934 1.1722351332627976 1.2911187869681524 1.0898201702641512 1.1923310242433502 1.0271685653796354 0.9120311413396727 1.0 13.876639146141024 -5.358813579222931 4.608906897190241 1.1098827397243862 0.7344032537214461 0.644099101878171 0.10639971654607856 0.12807720868320768 4.48621308161384 0.029674803778951105 0.0653136682905433 4.377099517052957e-06 5.358813579222931 -0.3754794860029401 IS(ph)YTPPESPVPSYASSTPLHVPVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISYTPPESPVPSYASSTPLHVPVPR 25 0 P41212 P41212 ETV6 Transcription factor ETV6 1 IS(0.534)Y(0.006)T(0.439)PPES(0.021)PVPSYASSTPLHVPVPR 106.43 3.3009e-07 25889000.0 10717.0 11141.0 12173.0 14871.0 18433.0 17008.0 14609.0 15732.0 14391.0 12080.0 True False 12531.176429601543 12247.00485169606 12463.250486359575 14037.826082432504 14821.185972397669 16116.070539127191 13225.129759999267 15319.051669431845 14601.44114990281 14270.008374772624 0.8781477978495729 0.8582338937759174 0.8733877485589185 0.9837293513610976 1.0386248965767566 1.1293665789025147 0.9267779956863545 1.073513852767864 1.0232258290553014 1.0 13.80069856105124 -5.866905537821049 2.89297145305904 1.034386907191304 0.8658299510356431 0.6877640505580784 0.04876194162307481 0.14196047066236558 2.3905950558485096 0.014208965920592776 0.023189163069542235 1.3586089216813928e-06 5.866905537821049 -0.16855695615566102 ISAAASDS(ph)GVESFDEGSSH ddPTM_PC-9_AZD4547_30min_R2 3 ISAAASDSGVESFDEGSSH 19 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 ISAAASDS(0.999)GVES(0.001)FDEGSSH;ISAAAS(0.005)DS(0.676)GVES(0.317)FDEGS(0.002)SH;ISAAAS(0.003)DS(0.978)GVES(0.02)FDEGSSH 316.54 1.0167999999999997e-156 7590000.0 10885.6 10415.22 29848.8 47433.5 34505.5 26441.7 17271.0 32616.8 24857.9 27252.4 True False 14346.994365454218 13781.736184272091 29452.985409140547 36498.43941526966 29715.006933285087 24788.296319017332 18808.085541639666 27576.623019500417 26171.83784559135 26298.301770984977 0.5455483205871231 0.5240542261735522 1.1199576940605398 1.3878629781158927 1.1299211330090437 0.942581636444919 0.7151825127503367 1.048608509387698 0.9951911752137108 1.0 14.682682019155143 -5.2569654316697685 24.843168472889914 1.0443597794039532 0.5348012020295768 0.6184030888252852 0.15949329633236145 245.43428140849394 1362846.2553780698 0.04675497732305408 0.11512910646265714 5.533941557127634e-06 5.2569654316697685 -0.5095585773743764 ISAAASDS(ph)GVESFDEGSSH ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISAAASDSGVESFDEGSSH 19 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 ISAAASDS(1)GVESFDEGSSH 265.64 2.799399999999999e-178 0.0 3018.5 3814.8 4983.9 5773.2 7169.8 6055.5 4686.4 5477.1 5049.7 5070.0 True False 3529.4724319074594 4193.508132865105 5102.735077546002 5449.746320966937 5764.929158839951 5737.938919901495 4242.470265402188 5333.331928467147 5123.542309406173 5989.150865902084 0.5893109909789944 0.7001840873202783 0.8519964168205053 0.909936390481307 0.9625620205464034 0.9580554987467741 0.7083592249371712 0.8904988449750535 0.8554705707241301 1.0 12.5481357587295 -5.1116926919466295 2.055661157677752 0.890864929947697 0.5820156545891144 0.6490260595515687 0.07541252995680375 0.2646262571998438 1.8815625264381357 0.021639020879805352 0.11789550665007867 7.732275296384057e-06 5.1116926919466295 -0.30884927535858253 ISAAASDS(ph)GVESFDEGSSH ddPTM_PC-9_Lapatinib_30min_R1 2 ISAAASDSGVESFDEGSSH 19 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 ISAAASDS(1)GVESFDEGSSH;ISAAAS(0.006)DS(0.994)GVESFDEGSSH 259.96 7.049999999999998e-66 4273600.0 12933.3 9801.1 21885.3 12382.2 15323.8 20141.1 10112.2 15120.900000000001 22158.9 7217.8 True False 12748.868770323252 9778.406155127786 20085.97511370106 13292.828293808328 14422.484211749948 19279.712104197286 10635.760236625392 15823.472215559375 19663.13133843843 8465.38711288604 1.5059995013006415 1.155104429925368 2.3727178504484603 1.5702564001561066 1.7037004946644434 2.2774755421225388 1.2563820289370589 1.8691965298873143 2.322768123445548 1.0 13.047360327156458 -5.223986928371778 24.999346541605583 1.814089613531718 1.3305518714980729 0.15398138622080548 0.43538107300308126 977.1807390449305 652260.9172124421 0.1041913070138549 0.2756498098605638 5.970532567425105e-06 5.223986928371778 -0.4835377420336451 ISAAASDSGVES(ph)FDEGSSH ddPTM_PC-9_AZD4547_30min_R2 2 ISAAASDSGVESFDEGSSH 19 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 ISAAASDS(0.001)GVES(0.999)FDEGSSH;ISAAASDSGVES(1)FDEGSSH 132.81 2.6680999999999997e-05 10312900.0 10164.0 10622.7 27524.0 44269.0 33790.0 27480.0 16512.6 41245.0 19278.2 26190.0 True False 13395.940575666624 14056.280036779548 27159.013776137872 34063.46599923202 29098.841757856095 25761.67125587979 17982.189410855142 34871.532965811944 20297.206294774664 25273.096071615586 0.5300474677778679 0.5561756263240841 1.0746215540501338 1.3478153172332918 1.1513762174368987 1.019331829502794 0.7115150973153258 1.3797887234313344 0.8031151481108251 1.0 14.625314791499724 -5.257725940339737 7.471702892447165 1.0743931633094077 0.5408622264113813 0.5243226415727238 0.19698316650110226 0.09074594237151073 42.477789656960006 0.05073637235952325 0.12126574081168165 5.524259353153249e-06 5.257725940339737 -0.5335309368980264 ISAAASDSGVES(ph)FDEGSSH ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISAAASDSGVESFDEGSSH 19 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 ISAAASDS(0.249)GVES(0.751)FDEGSSH 223.14 4.9067e-35 2882700.0 4824.8 6578.5 13714.0 13071.0 17271.0 13038.0 10726.0 11133.0 12070.0 7987.2 True False 5641.5433458562575 7231.570004208102 14040.993770634626 12338.67424675376 13886.871530910877 12354.264327912755 9709.95563048478 10840.770546388552 12246.500915803414 9435.216133359583 0.5979241244839912 0.7664445521963011 1.4881475497938668 1.3077256601604046 1.471812763441827 1.3093779891519868 1.0291185165492727 1.1489689682952176 1.297956585488712 1.0 13.203839850813683 -5.124714660807639 5.046839571458383 1.2638874123473005 0.6375547679261183 0.6902534473681511 0.15527731502288172 0.11906531603863645 4.290644055206268 0.041686705637543606 0.1193066299463869 7.503870650439417e-06 5.124714660807639 -0.6263326444211822 ISAAASDSGVES(ph)FDEGSSH ddPTM_PC-9_Lapatinib_30min_R1 2 ISAAASDSGVESFDEGSSH 19 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 ISAAASDSGVES(1)FDEGSSH;ISAAASDSGVES(1)FDEGSSH 262.42 2.9675999999999995e-67 6372000.0 17479.0 11384.0 27991.0 17879.1 17577.4 23185.0 13919.5 17403.8 25208.0 17055.8 True False 17229.746254743968 11357.641047430876 25689.688028384626 19193.988656929185 16543.531890498038 22193.431596874754 14640.183601363431 18212.44408369555 22368.809587991986 20003.872304575052 0.8613205479622754 0.5677721230420617 1.2842357538199831 0.959513656390386 0.8270164715415822 1.1094567721170132 0.7318674793787351 0.9104459279881633 1.118223974209036 1.0 14.28799168024225 -5.236787971294353 24.9999955034947 0.9771636300489744 0.7145463598790895 0.3166985241547827 0.1621039395559908 957.4450370569424 970980.7467022839 0.04039729860547653 0.10678186236239098 5.797116507733435e-06 5.236787971294353 -0.2626172701698849 ISAAASDSGVESFDEGS(ph)SH ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISAAASDSGVESFDEGSSH 19 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 ISAAASDSGVES(0.012)FDEGS(0.616)S(0.372)H 176.43 1.1313e-36 0.0 1771.2 1710.2 1583.0 3605.5 4243.1 4014.1 1052.9 3930.2 4050.6 1296.3 True False 2071.029177205399 1879.9773536819484 1620.7447235609304 3403.495524188714 3411.6950143482118 3803.5935295808104 953.1616896641265 3827.0364143911124 4109.832362017671 1531.308928494846 1.3524568025872183 1.227693066173013 1.0584048021936323 2.222605420014156 2.227959983033361 2.4838838583142318 0.6224489859149506 2.4991929082218456 2.6838688690056203 1.0 10.580549648262325 -5.758590718692224 24.99826318936984 2.0022236005544873 1.2143355878516684 0.226585829178914 0.6320554959441724 107.8100603199009 946059.2508172501 0.17409527573304395 0.2852250296666232 1.7434491346806535e-06 5.758590718692224 -0.7878880127028189 ISAPELLLHS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 2 ISAPELLLHSPAR 13 0 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 ISAPELLLHS(1)PAR;ISAPELLLHS(1)PAR 155.92 0.00011126 15647500.0 60942.0 54540.0 90697.0 127312.0 115507.0 97650.0 84379.0 102290.0 92476.0 107331.0 True False 80320.28832765389 72168.98841216994 89494.29851963303 97962.18535079245 99470.84684595077 91543.93006319723 91888.56753621766 86483.43089036025 97364.09256650419 103573.37435901359 0.7754916630334149 0.6967909354967284 0.8640666491121681 0.9458240204787456 0.9603901336762252 0.8838558232725042 0.8871832949818435 0.8349967491701591 0.940049440013547 1.0 16.660293651040732 -5.4130617471279034 4.281638393947079 0.9131026676175787 0.7377838192293441 0.7008916505090488 0.04755949435358297 0.12322989981899883 3.736650747086411 0.012809822627303263 0.027997350362399413 3.863120480686684e-06 5.4130617471279034 -0.17531884838823464 ISAPELLLHS(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ISAPELLLHSPAR 13 0 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 ISAPELLLHS(1)PAR;ISAPELLLHS(1)PAR 156.06 3.6852e-05 12360100.0 46015.0 57048.0 77552.0 76208.0 84094.0 80966.0 80121.0 73138.0 64663.0 56954.0 True False 53804.43066232295 62711.34842290249 79401.13379759787 71938.31282966949 67616.38437383018 76720.0004275031 72531.35885419254 71218.2049961164 65608.5740446227 67279.30935238408 0.7997173452021525 0.932104521086025 1.180171653988363 1.069248681684339 1.0050100844478147 1.1403208678268704 1.0780633682533833 1.0585454232757034 0.9751671751115831 1.0 16.037875275407004 -4.997549203457865 4.345508190603849 1.0669850156934793 0.8175520611896226 0.6610795020812676 0.05998098452400689 0.10723706642953765 5.06660991811995 0.015236326597505852 0.059520724828932156 1.0056591202478062e-05 4.997549203457865 -0.2494329545038566 ISAPELLLHS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 2 ISAPELLLHSPAR 13 0 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 ISAPELLLHS(1)PAR;ISAPELLLHS(1)PAR 151.39 3.7996e-05 11231900.0 61337.0 65380.0 70218.0 60591.0 66456.0 67019.0 52810.0 53484.0 68899.0 48114.0 True False 60462.32313217183 65228.61662693523 64444.94708931844 65047.06426565075 62547.18873752306 64152.75359891956 55544.24339868549 55969.061892941376 61138.86908136545 56430.4407921249 1.071448712493658 1.155911875067936 1.1420245205370076 1.1526945980320666 1.1083944739671743 1.1368465795835558 0.9842957563152142 0.9918239359340976 1.0834377372061503 1.0 15.784185998423384 -7.254412719521081 24.99737570968055 1.0142080176470536 1.1300449018002743 0.7241050242899305 0.034153406744089544 279.72723257561404 995132.7783040626 0.013042747250947244 0.009888991966252756 5.5665649467945616e-08 7.254412719521081 0.11583688415322069 ISAS(ph)SATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISASSATR 8 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;A0A1B0GV30;P49023-4;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 IS(0.25)AS(0.715)S(0.035)ATR 93.598 0.007104899999999999 87515000.0 129320.0 109600.0 111330.0 95247.0 110080.0 148810.0 172910.0 136170.0 129170.0 115050.0 True False 151211.32181357403 120480.36367883376 113984.52942137602 89910.61938494055 88510.61421589208 141006.14163496692 156530.71304000792 132595.681784041 131058.86688436857 135907.65426470098 1.1126034264344435 0.8864869630093077 0.8386910217681609 0.6615567009185946 0.651255550651357 1.0375143504451623 1.15174317360478 0.975630714115561 0.9643229264270234 1.0 17.05226718483761 -6.800363626139888 24.975665043353555 1.0321882147717536 0.824361946509241 0.3638749850575579 0.1291439815586834 185.6250791101882 119104.70155207142 0.049632315301741385 0.04377231016541417 1.5835667482644475e-07 6.800363626139888 -0.2078262682625126 ISCMSKPPAPNPT(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 1 ISCMSKPPAPNPTPPR 16 1 J3QR49;P46734;P46734-3 J3QR49 MAP2K3 Dual specificity mitogen-activated protein kinase kinase 3 1 ISCMSKPPAPNPT(1)PPR 62.916000000000004 0.025604000000000002 5996200.0 33233.0 25838.0 33159.0 45094.0 34088.0 34256.0 29538.0 42306.0 30031.0 34779.0 True False 43800.40271065812 34189.6282103712 32719.289994294286 34698.274995354994 29355.469601710545 32113.96690470953 32166.824777311827 35768.579795166435 31618.377350498376 33561.39779590371 1.3050827911584815 1.01871883937278 0.9749084407410408 1.0338745485621592 0.8746795881455656 0.9568721511542394 0.9584471115573711 1.0657654967973986 0.9421054969992196 1.0 15.034515183265905 -4.749639305492408 3.368843663379902 0.9759274744291085 1.3622389945819178 0.7999052103036388 0.04909724406434791 0.15428419865693682 2.627522416573894 0.012597265467646512 0.1621843526339793 1.779756937555499e-05 4.749639305492408 0.38631152015280923 ISDEDWDIIHR ddPTM_PC-9_AZD4547_30min_R2 2 ISDEDWDIIHR 11 0 E7ER27;A0A2R8YD50;P51659-3;P51659;P51659-2;A0A2R8YDT8;A0A2R8YF45 E7ER27 HSD17B4 Peroxisomal multifunctional enzyme type 2;(3R)-hydroxyacyl-CoA dehydrogenase;Enoyl-CoA hydratase 2 0 ; 155.97 0.00033171 7664800.0 39234.0 33263.0 56065.0 74272.0 58685.0 51046.0 49486.0 57427.0 46522.0 53746.0 False True 51709.59588210393 44014.61425658243 55321.541467779774 57149.73789096119 50537.600726835924 47854.08555049634 53890.158132915305 48552.9766911791 48981.05794345463 51864.36889900919 0.9970158122003444 0.8486484110563095 1.0666579511552994 1.101907515779161 0.9744185034863383 0.9226774868056004 1.0390593634302339 0.936152848706632 0.944406708945616 1.0 15.662456119166318 -9.417044355039861 13.588613873298437 0.9999999999807829 0.9818339966210633 0.006255726688146557 0.0706388242599563 0.0 0.0 0.07096378909333374 0.01721124694269821 3.827856469423997e-10 9.417044355039861 -0.01816600335971963 ISDEDWDIIHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ISDEDWDIIHR 11 0 E7ER27;A0A2R8YD50;P51659-3;P51659;P51659-2;A0A2R8YDT8;A0A2R8YF45 E7ER27 HSD17B4 Peroxisomal multifunctional enzyme type 2;(3R)-hydroxyacyl-CoA dehydrogenase;Enoyl-CoA hydratase 2 0 ;; 171.92 1.0420000000000001e-18 7108200.0 43030.0 41100.0 46726.0 53469.0 59967.0 49788.0 49011.0 49408.0 42748.0 34990.9 False True 50314.129118760306 45180.13637956265 47840.12504934181 50473.30527883692 48216.896826711396 47177.02963323521 44368.323271087975 48111.092352103224 43373.10862872941 41334.47318218802 1.217243749472579 1.093037672947331 1.1573904628826195 1.2210946794064146 1.16650565773968 1.1413482742430325 1.0733975748409275 1.163945942652909 1.0493204652096517 1.0 15.335057878963674 -8.397506742912269 0.5922556347305142 0.9972092953310958 1.1687473680069664 0.6037332058774367 0.043259341641799946 0.5973044411279848 0.5030279277906196 0.04517754000943154 0.0205777016232178 4.003992516317443e-09 8.397506742912269 0.17153807267587062 ISDEDWDIIHR ddPTM_PC-9_Lapatinib_30min_R1 1 ISDEDWDIIHR 11 0 E7ER27;A0A2R8YD50;P51659-3;P51659;P51659-2;A0A2R8YDT8;A0A2R8YF45 E7ER27 HSD17B4 Peroxisomal multifunctional enzyme type 2;(3R)-hydroxyacyl-CoA dehydrogenase;Enoyl-CoA hydratase 2 0 143.0 0.00012299 2681200.0 25526.0 25163.0 25397.0 19105.0 20388.0 23212.0 21208.0 17879.0 25780.0 17637.0 False True 25161.9945591049 25104.7366195101 23308.95669525506 20510.045432411705 19188.81792435022 22219.276869814814 22306.046468459037 18709.72361049844 22876.384924564958 20685.531950174718 1.216405486680867 1.2136374679645623 1.126824137343888 0.9915164609648083 0.9276444024050415 1.0741457808933523 1.0783404807856842 0.9044835615329878 1.1059123342666435 1.0 14.336334438017408 -5.549731719844898 3.031280065941836 1.0097604235263922 1.2126304593228048 0.6491817605727384 0.060698087775778266 0.15131637988244245 2.8283467671747435 0.016950311932054818 0.03528606474313527 2.82012449103637e-06 5.549731719844898 0.2028700357964126 ISDYFEFAGGSAPGTS(ph)PGR ddPTM_PC-9_AZD4547_30min_R2 1 ISDYFEFAGGSAPGTSPGR 19 0 Q86UE8-2;Q86UE8 Q86UE8-2 TLK2 Serine/threonine-protein kinase tousled-like 2 1 ISDYFEFAGGSAPGT(0.052)S(0.948)PGR 205.98 3.867199999999999e-72 0.0 17155.0 20228.0 25784.0 35563.0 30609.0 26508.0 20027.0 24871.0 24444.0 33218.0 True False 22609.933153833234 26766.305419900465 25442.087313033677 27364.499792872848 26359.46869979926 24850.45056953644 21809.364202560228 21027.758428723697 25736.059936584956 32055.047930772314 0.7053470393387892 0.8350106191607112 0.7936998680513497 0.8536720909596077 0.8223188047238765 0.7752429702555652 0.6803722224861688 0.6559889872614227 0.8028707363709403 1.0 14.96826394548049 -6.992917933200681 16.45535893711796 0.7520931026313947 0.8055056037796288 0.0 0.09594813033140405 8.270758601142884 19204.287210187304 0.03258852567304306 0.028494530467555824 1.016440747251785e-07 6.992917933200681 0.05341250114823404 ISDYFEYQGGNGS(ph)SPVR ddPTM_PC-9_AZD4547_30min_R2 3 ISDYFEYQGGNGSSPVR 17 0 Q9UKI8-5;Q9UKI8;Q9UKI8-2;B3KRP1;Q9UKI8-4;C9JWT6 Q9UKI8-5 TLK1 Serine/threonine-protein kinase tousled-like 1 1 ISDYFEYQGGNGS(0.5)S(0.5)PVR;ISDYFEYQGGNGS(0.5)S(0.5)PVR;ISDYFEYQGGNGS(0.743)S(0.257)PVR 201.9 5.78e-13 133942900.0 74261.0 59871.0 100164.0 124203.0 107780.0 107141.0 88013.0 115065.0 87841.0 99825.0 True False 97874.45327524394 79223.12990878298 98835.75991400496 95569.91726722111 92816.60741822212 100441.45633283183 95845.98649622666 97284.34818065609 92484.09592904421 96330.15713436522 1.0160312843539192 0.8224125472802805 1.0260105750283872 0.9921079764659401 0.9635259629936838 1.0426792535252694 0.9949738414994671 1.009905423957317 0.9600741728267259 1.0 16.555699898669538 -5.308452517923872 24.999997864188835 0.9989651530808968 0.9192213375178543 0.29318885644966763 0.04933422809124583 398.010910711195 211648.02693044153 0.011838370713413014 0.024643599444603752 4.915271166687888e-06 5.308452517923872 -0.07974381556304255 ISDYFEYQGGNGS(ph)SPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ISDYFEYQGGNGSSPVR 17 0 Q9UKI8-5;Q9UKI8;Q9UKI8-2;B3KRP1;Q9UKI8-4;C9JWT6 Q9UKI8-5 TLK1 Serine/threonine-protein kinase tousled-like 1 1 ISDYFEYQGGNGS(0.651)S(0.349)PVR;ISDYFEYQGGNGS(0.5)S(0.5)PVR;ISDYFEYQGGNGS(0.5)S(0.5)PVR;IS(0.001)DYFEYQGGNGS(0.731)S(0.268)PVR 149.52 2.7731999999999998e-05 87166000.0 94470.0 89324.0 111241.0 112722.0 128176.0 110801.0 108334.0 112013.0 115168.0 82416.0 True False 110461.9051324491 98191.49639824945 113893.40732384202 106406.55178965488 103060.83291911501 104990.4005059873 98071.81924976106 109072.77743758385 116852.11412355003 97357.368395303 1.134602413285632 1.0085676925814142 1.169848869182631 1.0929481100763654 1.0585827720882313 1.0784022024885849 1.007338436383748 1.1203340767666647 1.2002390373689225 1.0 16.57100255156209 -11.409565067544603 2.515146904585502 0.9519639949128065 1.092606264127448 0.1877795741062641 0.05981329112166914 99882457.05357742 53733803.21115661 28463061.045721147 0.01528059365050845 3.8943495680166206e-12 11.409565067544603 0.14064226921464162 ISDYFEYQGGNGS(ph)SPVR ddPTM_PC-9_Lapatinib_30min_R1 2 ISDYFEYQGGNGSSPVR 17 0 Q9UKI8-5;Q9UKI8;Q9UKI8-2;B3KRP1;Q9UKI8-4;C9JWT6 Q9UKI8-5 TLK1 Serine/threonine-protein kinase tousled-like 1 1 ISDYFEYQGGNGS(0.75)S(0.25)PVR;ISDYFEYQGGNGS(0.957)S(0.043)PVR 149.19 6.4897e-05 113426000.0 194693.0 160606.0 181150.0 167732.0 154825.0 180428.0 149602.0 147024.0 200204.0 137351.0 True False 191916.64211767624 160234.1266746036 166256.54625922145 180067.57081754968 145718.49789766155 172711.5150382108 157347.65955179202 153855.27177750008 177654.91727841727 161091.93734129658 1.1913485260970762 0.9946750242076016 1.032060008732671 1.1177938125857316 0.9045672943204838 1.0721301009143398 0.9767568889461441 0.9550774192474663 1.102816939261396 1.0 17.297524763336583 -4.757081479441146 24.929045785682646 1.0164380565402142 1.1913487949865422 0.40715410905853033 0.06299094073462115 123.37201922191117 705646.890705185 0.014912209861034918 0.11408693199516538 1.7495184248257213e-05 4.757081479441146 0.17491073844632798 ISDYFEYQGGNGSS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 3 ISDYFEYQGGNGSSPVR 17 0 Q9UKI8-5;Q9UKI8;Q9UKI8-2;B3KRP1;Q9UKI8-4;C9JWT6 Q9UKI8-5 TLK1 Serine/threonine-protein kinase tousled-like 1 1 IS(0.001)DYFEY(0.018)QGGNGS(0.374)S(0.606)PVR;ISDYFEYQGGNGS(0.245)S(0.755)PVR;ISDYFEYQGGNGS(0.024)S(0.976)PVR 199.31 1.9545e-12 16423500.0 37531.7 33175.2 57579.0 82366.0 69927.0 54843.0 49649.0 75458.0 44907.0 50830.0 True False 49465.999892143576 43898.43462360503 56815.46483854973 63377.791242014704 60218.843077881174 51413.65854025524 54067.66481714249 63797.69995233943 47280.69234054248 49050.4571714479 1.0084717400134153 0.8949648414114713 1.15830652994651 1.2920937927344476 1.2276917800663099 1.0481789876197718 1.102286664284448 1.3006545429198537 0.9639195038545819 1.0 15.581978962597573 -5.270516735475052 24.553993463412635 1.15179647929595 0.9517182893764876 0.2962448489002285 0.11207773505092496 497.9068266690558 1346826.85333689 0.028772524304666428 0.061338972964868586 5.363932012076019e-06 5.270516735475052 -0.20007818991946247 ISDYFEYQGGNGSS(ph)PVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISDYFEYQGGNGSSPVR 17 0 Q9UKI8-5;Q9UKI8;Q9UKI8-2;B3KRP1;Q9UKI8-4;C9JWT6 Q9UKI8-5 TLK1 Serine/threonine-protein kinase tousled-like 1 1 ISDYFEYQGGNGS(0.032)S(0.968)PVR 180.02 2.2452e-06 11663000.0 15496.0 10529.0 13128.0 17415.0 17028.0 14627.0 15197.0 12458.0 12120.0 10355.0 True False 18119.166740049022 11574.249536263145 13441.021308217256 16439.29401019179 13691.485636520785 13859.934370638126 13757.430143247913 12130.990700342092 12297.232071212706 12232.279529865098 1.481258394709759 0.9462054482980565 1.0988157420210203 1.343927268016993 1.1192914291316707 1.1330622666690302 1.1246824526580808 0.9917195458724019 1.0053099294525625 1.0 13.578405659946672 -7.521900217114225 1.2640812077476369 0.9876917992940628 1.1852033235443316 0.2780157648091982 0.1357684018723542 0.6803173213655275 2.046841477048618 0.09991509350861512 0.046264602176774465 3.006767053816861e-08 7.521900217114225 0.19751152425026874 ISDYFEYQGGNGSS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 3 ISDYFEYQGGNGSSPVR 17 0 Q9UKI8-5;Q9UKI8;Q9UKI8-2;B3KRP1;Q9UKI8-4;C9JWT6 Q9UKI8-5 TLK1 Serine/threonine-protein kinase tousled-like 1 1 ISDYFEYQGGNGS(0.035)S(0.965)PVR;ISDYFEYQGGNGS(0.326)S(0.674)PVR;ISDYFEYQGGNGS(0.171)S(0.829)PVR 238.88 1.3854e-37 18862700.0 76660.0 73922.0 79009.0 69494.0 64765.0 65685.0 61220.0 57911.0 76303.0 54808.0 True False 75566.8143422777 73750.83815075422 72513.18500355988 74604.82058518793 60955.6500328891 62875.8056692136 64389.67204823942 60601.756474499445 67708.95263378891 64281.48977293056 1.175561030231435 1.1473106552333092 1.1280570076970393 1.1605956994575537 0.9482613151656918 0.9781323658072887 1.0016829459878887 0.9427559424738056 1.053319592824709 1.0 15.9721157445163 -6.2558212448007025 24.999980534585738 0.9847513855989728 1.1507100688252816 0.8725037645412512 0.030983492322911945 147.49720584451384 656343.5391698392 0.008870542511184137 0.011131184851868385 5.548540433655285e-07 6.2558212448007025 0.1659586832263088 ISEAVKR ddPTM_PC-9_AZD4547_30min_R2 2 ISEAVKR 7 1 P30838;A8MYB8;C9JMC5;E9PNN6;C9JKT2;I3L3W9;I3L4E5;I3L1H6 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 0 ; 97.068 0.0085973 3931100.0 81226.0 78030.0 99986.0 156285.0 134346.0 113402.0 88937.0 104599.0 94358.0 101237.0 False True 107054.17839424418 103251.67154018363 98660.1203103083 120255.90782918019 115694.37688076135 106310.95501307398 96852.22070620146 88435.62799590173 99345.57124432514 97692.7234441445 1.0958255090047937 1.0569023761449075 1.009902445464292 1.230960747019568 1.1842681092508311 1.0882177429914413 0.9913964652810238 0.9052427333184596 1.0169188424880553 1.0 16.575963487884366 -7.25640298608627 3.731146812632269 0.9677067306361425 1.114407221650073 0.5114933755104967 0.06380605856730606 0.20090612694121532 6.280824583989812 0.029562532679701155 0.020757003354866844 5.541113090456358e-08 7.25640298608627 0.14670049101393057 ISEAVKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ISEAVKR 7 1 P30838;A8MYB8;C9JMC5;E9PNN6;C9JKT2;I3L3W9;I3L4E5;I3L1H6 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 0 ; 90.777 0.0099351 9551700.0 84884.0 58422.0 72479.0 97967.0 112516.0 117711.0 96522.0 84844.0 88931.0 88456.0 False True 99253.18466457928 64221.750062452804 74207.174238138 92478.2266032995 90469.29750286431 111538.02794162757 87378.73740123564 82616.93489964875 90231.44763407747 104492.37258268947 0.9498605707898519 0.6146070615023242 0.7101683348171137 0.8850237038126142 0.8657980986245856 1.0674274608260288 0.83622120200294 0.7906503877521807 0.8635218571831481 1.0 16.673038111109108 -5.778395815505151 15.319502993689147 0.8952573120178079 0.7438537801270128 0.26406080636424645 0.10830484404882638 3.3873349664556973 3060.1498426193775 0.030636904832176657 0.04600681164441103 1.6657283775433633e-06 5.778395815505151 -0.15140353189079514 ISEAVKR ddPTM_PC-9_Lapatinib_30min_R1 2 ISEAVKR 7 1 P30838;A8MYB8;C9JMC5;E9PNN6;C9JKT2;I3L3W9;I3L4E5;I3L1H6 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 0 ; 82.305 0.014348 13907900.0 115470.0 87725.0 95926.0 83789.0 88458.0 76878.0 69799.0 64738.0 92649.0 72785.0 False True 113823.37662539555 87521.87815230791 88039.33456506833 89951.12257191025 83255.0743551194 73590.10715137093 73412.85069087012 67745.96381768826 82213.893982778 85365.7902700838 1.333360544842102 1.0252570482321148 1.031318684996951 1.053713932563843 0.9752744523504506 0.8620561810362619 0.8599797466713952 0.7935961654352498 0.9630777589320768 1.0 16.38137041548945 -1.5228787472897718 0.4988365856345128 0.890668937195973 13.723076389951547 0.7283512614538123 0.07330157869193761 56.47753972143504 0.6020544768214543 0.0419787745768932 759.0162684877896 0.0299999998611932 1.5228787472897718 12.832407452755575 ISEEQQQLQQALAPAQASSNSSTPT(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISEEQQQLQQALAPAQASSNSSTPTR 26 0 Q13439-3;Q13439-4;Q13439;Q86W71;C9J0Y3;Q13439-5;E7EVX2;C9JHJ5 Q13439-3;Q13439-5 GOLGA4 Golgin subfamily A member 4 1 ISEEQQQLQQALAPAQAS(0.141)S(0.141)NS(0.164)S(0.164)T(0.164)PT(0.228)R 74.529 0.0064548 0.0 1693.5 2654.6 2229.4 4532.8 5056.6 5556.8 4762.7 5980.3 5118.1 4557.4 True False 1980.1761018503512 2918.1311443597824 2282.557351046584 4278.841911535877 4065.795529106822 5265.391625812671 4311.542577038022 5823.323461651618 5192.942530006086 5383.620543641447 0.36781494642840723 0.5420387861113958 0.42398184131727024 0.7947889114491149 0.7552158433433616 0.9780391435706933 0.8008630144132932 1.0816742031585977 0.9645818251695749 1.0 12.39436101201392 -5.958677058279555 0.7076350320443393 0.9971341461367458 0.3453841629499263 0.85258636161499 0.09137631991694846 0.320329622681489 0.30676860948398504 0.04824760703529866 0.13242480352455177 1.099823364963124e-06 5.958677058279555 -0.6517499831868194 down ISEGLPT(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 1 ISEGLPTPTK 10 0 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 ISEGLPT(0.883)PT(0.117)K 91.961 0.018918 18483000.0 101110.0 94569.0 111050.0 86746.0 102110.0 104420.0 93014.0 119460.0 91711.0 79937.0 True False 133260.87678135134 125136.57985241091 109577.40444121907 66748.04991234 87933.78904689792 97890.60089297571 101292.06580800592 101000.20191770849 96558.65622828269 77138.42996092918 1.7275549534628631 1.6222339489641275 1.4205293586701249 0.8653021580313218 1.1399478715270277 1.269025062378863 1.3131206567117146 1.309337018770869 1.251758122082468 1.0 16.235162161883345 -5.4315918660033 3.525396990050145 1.1841749498130894 1.6724464069713638 0.679172939020258 0.139737363747981 0.1488680277685686 3.4309465677307123 0.04037400654965287 0.09087812895924308 3.701758940739006e-06 5.4315918660033 0.48827145715827447 ISEGLPT(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ISEGLPTPTK 10 0 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 ISEGLPT(0.951)PT(0.049)K;ISEGLPT(0.956)PT(0.044)K;ISEGLPT(0.996)PT(0.004)K 96.334 0.013621000000000001 68524000.0 359740.0 460100.0 411090.0 366770.0 429020.0 338560.0 415360.0 279402.0 307189.0 308483.0 True False 420636.87681112776 505775.68730503076 420891.94466750615 346221.06598438334 344956.6107458387 320805.317599183 376014.0938540137 272067.9935508893 311681.05798050895 364408.5259499162 1.1543003164227268 1.3879359325817306 1.155000266720853 0.9500904653146548 0.9466205815207767 0.8803452574632517 1.031847684885651 0.7466016137840912 0.8553067115211952 1.0 18.47519718824683 -5.690299299332191 2.728787780807418 0.904849479737888 1.274125686951084 0.7234680243904537 0.0915333001378496 0.12949392673567714 1.9481916312814491 0.026085460290417896 0.04944668738701833 2.040331340840028e-06 5.690299299332191 0.369276207213196 ISEGLPT(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 2 ISEGLPTPTK 10 0 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 ISEGLPT(0.805)PT(0.195)K;ISEGLPT(0.851)PT(0.149)K 105.65 0.0059415 51574000.0 265540.0 326150.0 318420.0 289910.0 311660.0 320960.0 320890.0 338500.0 314760.0 288000.0 True False 261753.3509059278 325394.8197135962 292240.73673674447 311230.94851141004 293328.77154713514 307233.2889943032 337504.1140731712 354227.945755004 279308.41423025884 337780.416264122 0.7749216304513461 0.9633324018973288 0.8651796334700218 0.9214002160150337 0.8684007639974349 0.9095651322605602 0.9991820064821795 1.0486929635317317 0.8268934514304644 1.0 18.365726160842392 -7.096478964427101 4.7391631963162055 0.9721490604547844 0.8852319357019232 0.26704983328678045 0.06984333900116582 0.31575192695782067 11.647803548799237 0.025941148970647393 0.020084603915633086 8.007944150030631e-08 7.096478964427101 -0.08691712475286129 ISEGLPTPT(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 ISEGLPTPTK 10 0 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 IS(0.001)EGLPT(0.299)PT(0.701)K 94.402 0.015444 22334000.0 131070.0 122680.0 151130.0 131760.0 135990.0 136210.0 135920.0 163560.0 123920.0 127060.0 True False 172747.5335746388 162333.9108618446 149125.91745341205 101384.7676717073 117110.135858267 127692.76716751793 148016.6166880704 138285.56023489416 130470.15821230608 122611.66807405422 1.408899628298865 1.3239678850449959 1.2162457276361653 0.826876995185104 0.9551304349561214 1.0414405837003609 1.2071984584588824 1.127833610022933 1.0640925146985647 1.0 16.903736750949918 -5.537982133475831 7.405459894052237 1.0397462144416818 1.34374775524771 0.6585847103388844 0.09754859760910949 0.09922446334338424 28.42618222684073 0.029992594855148994 0.05385629322935112 2.897462784527906e-06 5.537982133475831 0.30400154080602815 ISEGLPTPTKMT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 ISEGLPTPTKMTPR 14 1 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 ISEGLPT(0.001)PT(0.08)KMT(0.92)PR;ISEGLPT(0.036)PT(0.162)KMT(0.802)PR;ISEGLPT(0.002)PT(0.207)KMT(0.792)PR 107.51 0.00055774 98045000.0 234773.0 205220.0 359360.0 485790.0 387120.0 288093.0 285505.0 372150.0 221664.0 318867.0 True False 309425.9304182383 271553.35170417133 354594.6515983475 373798.6208806825 333375.07017760427 270078.49916740146 310914.3919035286 314642.7686562467 233380.70650397483 307703.5633855609 1.0055974880944725 0.8825161097140356 1.1523904620955945 1.2148010792202062 1.0834293451450099 0.8777230143057713 1.010434810967543 1.0225515921698665 0.7584595509267551 1.0 18.231181625449544 -6.747610114672002 24.953823975860214 0.940030831848454 1.0703284224519283 0.2718889303245491 0.10929539232012411 355.4072078841515 641303.2812890526 0.03855506291192958 0.03836117505940577 1.7880921037315466e-07 6.747610114672002 0.13029759060347423 ISEGLPTPTKMT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 ISEGLPTPTKMTPR 14 1 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 ISEGLPT(0.001)PT(0.086)KMT(0.914)PR;ISEGLPTPT(0.069)KMT(0.93)PR 89.50200000000001 0.0038196999999999997 51379000.0 188984.0 127490.0 162602.0 155141.0 128656.0 142316.0 125869.0 99290.0 147515.0 98484.0 True False 186289.0535045786 127194.80473796214 149233.491221871 166550.58667520445 121088.70702742811 136229.4764347996 132385.88093825305 103903.37587596587 130900.30729818456 115506.82817831864 1.612796892119545 1.1011886201359429 1.2919884787372515 1.441911177909628 1.0483250984997372 1.1794062618054881 1.146130345938308 0.89954314835449 1.1332689968432132 1.0 16.817618613418603 -1.5228787452808157 0.20765044085123172 0.9605815629135085 3.444868999056472 0.5064960842465556 0.14156539329701517 45.20870300035684 0.558994127667608 0.24325313870383863 36.960017743134706 0.029999999999966973 1.5228787452808157 2.484287436142963 ISEIEDAAFLAR ddPTM_PC-9_Lapatinib_30min_R1 1 ISEIEDAAFLAR 12 0 B0QZ43;E5RHW4;O94905;O75477 B0QZ43 ERLIN1;ERLIN2 Erlin-2;Erlin-1 0 118.28 0.0027281 859090.0 4077.8 3538.5 6642.4 5008.2 6351.7 4660.4 4190.0 3861.8 4966.7 3908.2 False True 4019.649824223066 3530.3068206547914 6096.287512405486 5376.51973486544 5978.105493922668 4461.085555923014 4406.937698172544 4041.233326194024 4407.297944330362 4583.727162650838 0.8769391548816449 0.7701825818561945 1.3299848128133158 1.172958063183699 1.304201860580515 0.973244130294854 0.9614310672941417 0.881647877980791 0.9615096597026852 1.0 12.162305457726116 -6.974512505375991 24.992948106692264 0.9450062174516953 1.0956685681163714 0.1472364010027296 0.16301175439482882 458.5935974687411 449693.85697376943 0.06308510009393019 0.055634182665598955 1.060443402791178e-07 6.974512505375991 0.15066235066467604 ISELDSMMSESDNSKS(ph)PCNNGFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISELDSMMSESDNSKSPCNNGFK 23 1 Q5W0B1 Q5W0B1 RNF219 RING finger protein 219 1 ISELDS(0.01)MMS(0.011)ES(0.073)DNS(0.084)KS(0.823)PCNNGFK 54.637 0.0049457 4494600.0 22409.0 22040.0 21145.0 23691.0 24812.0 23088.0 29268.0 21408.0 23391.0 21313.0 True False 26202.40110207531 24227.98554271439 21649.17699285905 22363.67007725831 19950.26671443231 21877.224635898892 26495.523158029886 20846.06268365095 23733.049123575598 25176.87818638484 1.0407327273897307 0.9623109490920286 0.8598832957998144 0.8882622345669584 0.7924043071082982 0.8689411162869932 1.0523752373857909 0.8279844120993559 0.9426525778088708 1.0 14.619811786346009 -10.226242625738054 15.227067063790415 0.9999999967038742 0.910553003673904 0.08685638318049016 0.08145066462920461 0.0 0.0 0.08074884770245765 0.01958447224847923 5.939602402746882e-11 10.226242625738054 -0.08944699302997017 ISEQFTAMFR ddPTM_PC-9_Lapatinib_30min_R1 1 ISEQFTAMFR 10 0 P04350;P68371;A0A0B4J269;Q13509;Q13509-2;Q5JP53;P07437;Q5ST81;Q9BVA1;Q13885 P04350;P68371;A0A0B4J269;Q5JP53 TUBB4A;TUBB4B;TUBB3;TUBB;TUBB2B;TUBB2A Tubulin beta-4A chain;Tubulin beta-4B chain;Tubulin beta-3 chain;Tubulin beta chain;Tubulin beta-2B chain;Tubulin beta-2A chain 0 94.363 0.024515000000000002 0.0 16478.0 13306.0 17231.0 12111.0 12841.0 16523.0 11941.0 11192.0 14578.0 12609.0 False True 16243.02069830489 13275.190774518196 15814.333693583498 13001.683341111646 12085.717626377338 15816.349806994242 12559.246552238277 11712.021178404762 12936.072126854464 14788.448849563603 1.0983586489386417 0.8976729682443969 1.0693706861656533 0.8791783014819243 0.8172403846623832 1.0695070164482443 0.8492605735731974 0.7919709022593249 0.8747416485966477 1.0 13.852183116611124 -1.522878745281091 0.47784563089369164 0.8866554656032528 5.865541968779159 0.2378356890787423 0.09438082532919985 144.2661926208607 1.6257440913838328 0.05505909271754554 712.590587478282 0.029999999999947954 1.522878745281091 4.9788865031759055 ISES(ph)PEPGQR ddPTM_PC-9_AZD4547_30min_R2 2 ISESPEPGQR 10 0 O14867;H7C4B6 O14867 BACH1 Transcription regulator protein BACH1 1 IS(0.012)ES(0.988)PEPGQR;IS(0.194)ES(0.806)PEPGQR 89.266 0.009459 19277500.0 65738.0 69158.0 95937.0 107543.0 105318.0 102288.0 67393.0 98325.0 73948.0 82291.0 True False 86641.31656465691 91511.97104159958 94664.81269587777 82750.62287278699 90696.41362100889 95891.91519000827 73390.84644245986 83131.13053372428 77856.74031216584 79410.01713743088 1.091062811568359 1.152398328830788 1.1921016530199986 1.042067812799671 1.1421281204869307 1.207554394857427 0.924201367636605 1.0468594962000002 0.980439787305714 1.0 16.27703338645115 -7.262188785437313 24.999939306690898 0.9917801203303699 1.136847058261425 0.6647896407683707 0.05215212234972439 43.32812508440154 1445375.6686868337 0.020840485084133158 0.014992011885907989 5.4677822971943756e-08 7.262188785437313 0.14506693793105507 ISES(ph)PEPGQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ISESPEPGQR 10 0 O14867;H7C4B6 O14867 BACH1 Transcription regulator protein BACH1 1 IS(0.013)ES(0.987)PEPGQR;IS(0.001)ES(0.999)PEPGQR 78.903 0.019759 12565300.0 62017.0 61089.0 60997.0 75459.0 78839.0 80626.0 69160.0 64383.0 56677.0 50209.0 True False 72515.2532084164 67153.51219686387 62451.39981241072 71231.27687137864 63391.06390049689 76397.8306260388 62608.66412496054 62693.01446942726 57505.79390265038 59311.49424577469 1.2226172031331404 1.132217507766597 1.052939242326705 1.2009691844250425 1.0687821088745009 1.2880779956320412 1.0555907403971827 1.0570128988765692 0.9695556423575866 1.0 15.856024097886602 -7.503840194769004 22.70572144654089 1.0192308041621227 1.1539744594588148 0.5063995934616015 0.06863544106727199 201.3620105945729 240150.31604046462 0.0284386457307361 0.018770806021617677 3.134438876391045e-08 7.503840194769004 0.13474365529669208 ISES(ph)PEPGQR ddPTM_PC-9_Lapatinib_30min_R1 2 ISESPEPGQR 10 0 O14867;H7C4B6 O14867 BACH1 Transcription regulator protein BACH1 1 IS(0.076)ES(0.924)PEPGQR;IS(0.01)ES(0.99)PEPGQR 93.839 0.0065373 19429700.0 120705.0 103417.0 118510.0 102285.0 102521.0 116474.0 79492.0 117023.0 108150.0 82284.0 True False 118983.72456541375 103177.54429042153 108766.56526182903 109807.38011275769 96490.91634404109 111492.67853415533 83607.70680265673 122460.31579346467 95969.00813001166 96506.679763462 1.2329066221845266 1.0691233450711373 1.1270366520578268 1.1378215516469505 0.9998366598098749 1.1552845751964946 0.8663411383292776 1.2689309806700952 0.9944286588786582 1.0 16.558341182325016 -1.5228787452803376 0.6621819689753381 1.0625216721156483 15.244986527034985 0.1747111838368247 0.10592299088136072 447.5361418180583 2.757351443793893 0.04100908191861179 9329.420059726499 0.029999999999999995 1.5228787452803376 14.182464854919337 ISFPGS(ph)SESPLSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISFPGSSESPLSSK 14 0 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 ISFPGS(0.753)S(0.123)ES(0.123)PLS(0.001)SK 121.56 7.047399999999999e-05 4167900.0 40709.0 38772.0 40462.0 42683.0 54661.0 50911.0 49339.0 46447.0 48433.0 38848.0 True False 47600.22966059993 42621.02792477868 41426.767532989536 40291.60989015308 43950.56943727169 48241.137536306655 44665.252736573566 45227.81546466441 49141.24099876607 45890.83487940118 1.0372491541217532 0.928748148443684 0.9027242071724563 0.877988164652864 0.9577199794418991 1.051215077326049 0.9732935313543895 0.9855522477096101 1.070829090991846 1.0 15.48591843309448 -6.57151405568391 7.146455683060799 1.0121183349475706 0.9317309426150728 0.3922621139263752 0.04713327863469772 0.2264554514487295 26.75638904977859 0.015977480448291462 0.016024967198131367 2.6821677994301196e-07 6.57151405568391 -0.08038739233249781 ISFPGSSES(ph)PLSSK ddPTM_PC-9_AZD4547_30min_R2 2 ISFPGSSESPLSSK 14 0 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 ISFPGS(0.113)S(0.077)ES(0.81)PLS(0.001)SK;ISFPGS(0.05)S(0.114)ES(0.75)PLS(0.086)SK 199.38 6.1999e-08 18903000.0 71400.0 70688.0 97824.0 112542.0 110981.0 111942.0 83080.0 100446.0 82860.0 92715.0 True False 94103.71478774076 93536.51362081894 96526.78984293375 86597.18065656706 95573.20382150434 104942.24904387545 90473.95905271379 84924.37871945542 87239.81043795723 89469.07607024946 1.0518015712362143 1.0454619375679681 1.0788843931633172 0.9679006921740485 1.0682261181110446 1.1729443697560566 1.0112316235575667 0.949203707577961 0.9750833949537844 1.0 16.44910149757635 -7.517543430270549 24.60738459604308 0.9733296367239397 1.062512765352187 0.41554090013145983 0.04811357505865117 201.4094819974733 928950.2202978246 0.02300240032036878 0.013803931389256662 3.037082362772466e-08 7.517543430270549 0.0891831286282474 ISFPGSSES(ph)PLSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISFPGSSESPLSSK 14 0 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 ISFPGS(0.01)S(0.052)ES(0.937)PLS(0.001)SK 154.13 7.3538e-09 0.0 18596.0 19501.0 19028.0 16769.0 20043.0 18345.0 24187.0 21627.0 17221.0 12716.0 True False 21743.935512258115 21436.930402380836 19481.69968409186 15829.48729583153 16115.718029879366 17382.955905473198 21895.8322612843 21059.314165700638 17472.82454606882 15021.310140199388 1.4475392165739207 1.427101244984766 1.2969374510120637 1.0538020417719312 1.0728570197582947 1.1572196927719156 1.457651300513902 1.4019625431567784 1.16320243593858 1.0 13.874723027976774 -5.390686611485958 3.6574994426172 1.2070683873781847 1.4379036807526435 0.3345457445049126 0.13826231872663516 0.31808243946514675 7.535748442540535 0.04104013632027368 0.09406614404621552 4.0673672602921455e-06 5.390686611485958 0.23083529337445885 ISFPGSSES(ph)PLSSK ddPTM_PC-9_Lapatinib_30min_R1 1 ISFPGSSESPLSSK 14 0 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 ISFPGS(0.026)S(0.057)ES(0.909)PLS(0.008)S(0.001)K 128.85 2.4416999999999997e-05 5167400.0 28168.0 21929.0 26922.0 24642.0 23570.0 23933.0 20006.0 20938.0 25314.0 17238.0 True False 27766.31915462146 21878.224747813736 24708.577081925294 26454.254883302237 22183.658940402926 22909.44138054791 21041.81278989019 21910.855917926983 22462.8707517625 20217.56533180881 1.3733760073937291 1.0821394361165815 1.2221341529709642 1.3084787633494663 1.0972468037731926 1.1331454111590726 1.0407688781786484 1.0837534370893847 1.1110571615871616 1.0 14.303321652991674 -6.37007426776937 6.355421381195077 1.0812056191428774 1.2326433293860604 0.5293095593151305 0.0776182743842339 0.2139081596999564 10.838661486042929 0.023680605048358068 0.026866953866685108 4.265065765885657e-07 6.37007426776937 0.15143771024318298 ISFPPSCPDAVVATPPGAS(ph)PPVKDR ddPTM_PC-9_AZD4547_30min_R2 3 ISFPPSCPDAVVATPPGASPPVKDR 25 1 Q8N4X5-2;Q8N4X5;Q8N4X5-4;Q8N4X5-3 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 ISFPPSCPDAVVAT(0.021)PPGAS(0.979)PPVKDR;ISFPPSCPDAVVAT(0.328)PPGAS(0.672)PPVKDR;ISFPPSCPDAVVAT(0.263)PPGAS(0.737)PPVKDR 116.65 3.6249e-09 57393000.0 213839.5 190143.8 263959.8 341766.0 334827.0 289033.0 234978.0 284305.0 227281.9 278435.4 True False 281836.01286208775 251604.0648853311 260459.52058373048 262977.12893206376 288342.0505847192 270959.7208188034 255890.58678729658 240372.19492896498 239295.55722880465 268687.46139514016 1.04893623021586 0.9364190780578121 0.96937728032158 0.978747305760284 1.0731503773474358 1.0084568867183632 0.9523726394175719 0.8946163459986178 0.8906093197884256 1.0 18.03556947235981 -7.45791284321191 3.977054424582168 0.9196277450921577 0.9997313675377909 0.3454250292610186 0.046104361533718954 0.250698528608191 7.779366274729899 0.0216795639425008 0.0135744415164772 3.4840722844598526e-08 7.45791284321191 0.08010362244563318 ISFPPSCPDAVVATPPGAS(ph)PPVKDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ISFPPSCPDAVVATPPGASPPVKDR 25 1 Q8N4X5-2;Q8N4X5;Q8N4X5-4;Q8N4X5-3 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 ISFPPSCPDAVVAT(0.007)PPGAS(0.993)PPVKDR;ISFPPSCPDAVVAT(0.001)PPGAS(0.999)PPVKDR;ISFPPSCPDAVVAT(0.002)PPGAS(0.998)PPVKDR;ISFPPS(0.001)CPDAVVAT(0.096)PPGAS(0.904)PPVKDR 155.63 7.8238e-10 53137800.0 192577.2 175864.8 201193.7 253773.8 270039.2 224986.3 243943.9 210164.4 218808.4 197691.7 True False 225176.7163869236 193323.4950940275 205990.92083935626 239555.67673175992 217126.95725261702 213187.62236225477 220835.7677911072 204647.80718758822 222008.05890517693 233531.64028336352 0.9642235892048624 0.8278257064415421 0.8820685736177342 1.0257953759117477 0.9297539168104103 0.9128853893355793 0.9456353217197835 0.8763172602190944 0.9506551601992601 1.0 17.833258502690704 ISFPPSCPDAVVATPPGAS(ph)PPVKDR ddPTM_PC-9_Lapatinib_30min_R1 2 ISFPPSCPDAVVATPPGASPPVKDR 25 1 Q8N4X5-2;Q8N4X5;Q8N4X5-4;Q8N4X5-3 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 ISFPPSCPDAVVAT(0.008)PPGAS(0.992)PPVKDR;ISFPPSCPDAVVAT(0.231)PPGAS(0.769)PPVKDR 133.91 1.8114999999999998e-07 43808000.0 202932.0 164414.0 184756.0 158587.0 177630.0 169431.0 152859.0 160410.0 183136.0 134423.0 True False 200038.15246682882 164033.30948456578 169566.07485878456 170250.01701072347 167182.15263401665 162184.83109295156 160773.29107516858 167863.23420549548 162509.29517242548 157657.83644261115 1.2688119853759663 1.0404386688655045 1.0755321694428308 1.0798703118870718 1.0604113084786142 1.0287140477916445 1.019760861260401 1.064731306690227 1.0307720747619185 1.0 17.266437355944987 -4.76028110825343 24.999975106680672 1.0478034953044078 1.2688122490183036 0.8824085597794757 0.024541702473768374 9.34211771747242 201551.9925378942 0.006216798540205663 0.03720983570065905 1.7366763565079254e-05 4.76028110825343 0.22100875371389583 ISGLIYEETR ddPTM_PC-9_AZD4547_30min_R2 2 ISGLIYEETR 10 0 P62805 P62805 HIST1H4A Histone H4 0 ; 110.38 0.0080524 24022800.0 51676.0 47440.0 52007.0 53461.0 42055.0 39400.0 34316.0 52656.0 25807.0 27801.0 False True 68107.89307242699 62774.05226023719 51317.35319922984 41136.392414216345 36216.38917214082 36936.31177153068 37370.05752109935 44519.22511450586 27171.105333965283 26827.695451965836 2.5387157534411435 2.339897303986927 1.9128498491833554 1.533355426964265 1.3499627367168066 1.3767977886011122 1.3929656234546604 1.6594502198005106 1.0128005732961414 1.0 14.711435509331716 -5.436764187214682 1.1808036563389104 1.3252480595770226 2.634142905856032 0.8654329129233362 0.17945362452639857 0.22151959263623092 0.5108582095893496 0.058286140847426185 0.27007625696130455 3.6579335581223655e-06 5.436764187214682 1.3088948462790095 up ISGLIYEETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ISGLIYEETR 10 0 P62805 P62805 HIST1H4A Histone H4 0 ;;;; 122.96 0.0022804 35214600.0 60921.1 81831.0 51158.2 104481.0 96652.0 88806.0 106532.0 95033.0 63804.7 57658.4 False True 71233.83898342802 89954.64087776124 52378.00550655392 98627.26830197219 77713.73442218718 84148.85702597178 96440.51773511137 92538.48444578687 64737.72303086676 68111.41149635673 1.045842942004488 1.3206985276259162 0.7690048459699828 1.4480285481566881 1.1409796495899087 1.235459010131847 1.4159230533677893 1.3586340733921913 0.9504680876321228 1.0 16.05560890950458 -4.716966442114635 22.904917198630862 1.196425480029207 1.0458377205493197 0.032738217246153556 0.2096671128501451 14279.225467739261 7352706.992825078 0.05046829524187187 21.798652062508104 1.918817001714276e-05 4.716966442114635 -0.15058775947988723 ISGLIYEETR ddPTM_PC-9_Lapatinib_30min_R1 2 ISGLIYEETR 10 0 P62805 P62805 HIST1H4A Histone H4 0 ; 118.03 0.0041792999999999995 13665400.0 46756.0 36584.0 20606.0 19698.1 20091.2 22126.0 50678.0 15585.7 22664.0 16940.7 False True 46089.25086599972 36499.29199571427 18911.854221460242 21146.763984935293 18909.47511681899 21179.722558225163 53301.85887064158 16309.868520395188 20111.34165749961 19868.87742293615 2.3196706026680403 1.8370082626600923 0.9518330512034291 1.0643159920310334 0.9517133109387624 1.065974796028275 2.6826809454826677 0.8208751895347379 1.0122032175951503 1.0 14.27822274322342 -5.028458922609516 3.6789755615200406 1.224728906955166 2.2672552577193907 0.34138043305223253 0.5097472887037348 0.26490462753105 7.48233955914412 0.13674822269327216 0.5340370357773475 9.365718005874014e-06 5.028458922609516 1.0425263507642248 ISHSLYSGIEGLDES(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 3 ISHSLYSGIEGLDESPSR 18 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3;B1AP52 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 ISHSLYSGIEGLDES(0.866)PS(0.134)R;ISHSLYSGIEGLDES(0.997)PS(0.003)R;ISHSLYSGIEGLDES(0.851)PS(0.149)R 212.34 1.3524999999999997e-67 30677000.0 27635.2 28880.7 65752.1 99145.0 72341.8 69325.6 49224.0 76930.0 57699.7 69936.0 True False 36422.61875213128 38215.8214821297 64880.18419234113 76288.65202498039 62298.38978036323 64990.65927280278 53604.84064047657 65042.2361755343 60749.58834572782 67487.56192686185 0.539693800045755 0.5662646625691599 0.9613650625377991 1.1304105504308561 0.9231092071140121 0.963002032037177 0.7942921496937411 0.9637662751252206 0.9001597718341617 1.0 16.042334015047437 -5.2546749177341185 7.864513658100919 0.9531550482728003 0.5515154812264729 0.8033391186915526 0.07947116460828607 0.055809173553933784 30.470642051645854 0.021706851227389207 0.05246266066597732 5.5632052382477174e-06 5.2546749177341185 -0.4016395670463274 ISHSLYSGIEGLDES(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ISHSLYSGIEGLDESPSR 18 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3;B1AP52 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 ISHSLYSGIEGLDES(0.825)PS(0.175)R;ISHSLYSGIEGLDES(0.862)PS(0.138)R 166.93 5.933500000000001e-25 9831900.0 21075.1 24222.0 33594.0 35001.0 31401.0 34219.0 32758.0 28588.0 29517.0 23493.0 True False 24642.698177801194 26626.600082378758 34395.00836595445 33040.00744477304 25248.199463964578 32424.495400893302 29654.925092617956 27837.595291489786 29948.63028432222 27752.094929514344 0.8879581249772136 0.959444688770554 1.239366197518133 1.1905410214504204 0.9097763440234246 1.1683620816102738 1.0685652801324181 1.003080861541898 1.0791484520497174 1.0 14.760309060213787 -5.015732934070361 23.235570630008134 1.0838552570185618 0.9058295695869797 0.32778111005772415 0.0933498309226781 277.3167448621652 409573.23605107056 0.023927789021405015 0.06827986394565283 9.644219048739359e-06 5.015732934070361 -0.1780256874315821 ISHSLYSGIEGLDES(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 1 ISHSLYSGIEGLDESPSR 18 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3;B1AP52 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 ISHSLYSGIEGLDES(0.868)PS(0.132)R 181.64 2.6102e-09 12105000.0 17275.0 13816.0 26257.0 16268.0 22309.0 19114.0 14466.0 15331.0 25698.0 15505.0 True False 17028.655332152997 13784.00990085251 24098.25081495105 17464.402988457132 20996.828481181532 18296.538776910227 15214.978697318391 16043.334228567126 22803.620628063236 18185.01859088616 0.93641121382671 0.7579871217597041 1.3251705349934833 0.9603731170893506 1.1546223269578935 1.0061325307679343 0.8366765544547602 0.8822280905782308 1.2539784061310664 1.0 14.150462780237978 -5.162732624916779 22.346045773374676 1.0394343909868529 0.8471981234207948 0.2218157545268341 0.15218652110945868 29.25709407260497 6616.413438568963 0.03856126449512282 0.10202422988990718 6.874915666021436e-06 5.162732624916779 -0.19223626756605805 ISINQT(ph)PGK ddPTM_PC-9_AZD4547_30min_R2 2 ISINQTPGK 9 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;H0YDG6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 ISINQT(1)PGK;IS(0.063)INQT(0.937)PGK 109.16 0.0058376999999999995 157181000.0 207410.0 192816.0 216940.0 232250.0 216290.0 189783.0 209168.0 208780.0 199355.0 198736.0 True False 273362.0656039964 255140.0012776118 214063.23385392208 178708.35072673048 186261.8669371616 177915.83900853802 227783.54678789212 176517.84828711904 209892.49830870118 191778.31313053053 1.4254065600104497 1.3303902673497563 1.1162014638653315 0.931848590226653 0.9712352971338617 0.9277161536374696 1.1877440314789673 0.9204265352306821 1.0944537726006671 1.0 17.549080059714576 -5.286769234960685 2.408163984497958 1.0046353158038093 1.4117774333035453 0.7758462423794656 0.07962537134016613 0.13412561870149922 1.475259710338951 0.021527772146190345 0.07023317898703983 5.166908431956717e-06 5.286769234960685 0.40714211749973606 ISINQT(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISINQTPGK 9 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;H0YDG6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 IS(0.164)INQT(0.836)PGK 89.9 0.021978 16259000.0 76400.0 81559.0 76561.0 83414.0 90158.0 73390.0 81605.0 86792.0 78386.0 70643.0 True False 89333.01103121758 89655.63851534671 78386.50459920932 78740.58401183673 72492.1871046184 69541.29920428878 73874.7836309631 84513.80196372543 79532.2469582573 83450.0166903197 1.0704972218607156 1.0743633383328834 0.9393228151181694 0.9435658270032525 0.8686899054033093 0.8333287632805909 0.8852578652573554 1.0127475741239622 0.9530524991193098 1.0 16.34862471768183 -5.2956224296143635 3.806678506280918 0.9216654332424877 1.0757688217721582 0.5371533040690109 0.052851299423743496 0.17018154234340505 5.356109906065316 0.015448385502058815 0.03851455137724363 5.0626461108028485e-06 5.2956224296143635 0.15410338852967043 ISINQT(ph)PGK ddPTM_PC-9_Lapatinib_30min_R1 4 ISINQTPGK 9 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;H0YDG6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 IS(0.005)INQT(0.995)PGK;IS(0.005)INQT(0.995)PGK;IS(0.009)INQT(0.991)PGK;ISINQT(1)PGK 119.74 0.004203 185498000.0 498115.0 462410.0 483179.0 490521.0 480631.0 471088.0 435315.0 444186.0 458648.0 374874.0 True False 491011.7887568957 461339.318055386 443453.88774487755 526595.5506700865 452361.22953690303 450940.6643997645 457853.4806873465 464824.5031407161 406990.2324624459 439670.47141179285 1.1167722662389508 1.049284289149585 1.0086051181034197 1.1977050652939576 1.0288642493646658 1.0256332724637676 1.0413559937677133 1.0572111009596643 0.9256710625928326 1.0 18.746063117794087 -7.60633295339141 0.8368913426974972 0.9765544713365417 1.0798181824771214 0.32231227706680665 0.05636195763973652 0.806185349239547 1.0449878919632603 0.04975680369014045 0.023633128997296395 2.4755234611786868e-08 7.60633295339141 0.10326371114057964 ISKPGAVS(ph)TPVK ddPTM_PC-9_AZD4547_30min_R2 1 ISKPGAVSTPVK 12 1 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 ISKPGAVS(0.5)T(0.5)PVK 93.181 0.0025747 67224000.0 96639.0 103860.0 117540.0 95480.0 103250.0 125630.0 96303.0 133310.0 114480.0 119960.0 True False 127368.19178392841 137430.71390700337 115981.34280072847 73468.56115129498 88915.5197247304 117774.33624003545 104873.78043636859 112710.0026590469 120531.17908444781 115760.23691298235 1.1002758389279372 1.18720138772963 1.0019100331309128 0.6346614615735603 0.7681007062171851 1.0173988873966033 0.9059568573205566 0.9736504145527248 1.0412139979901027 1.0 16.82078025401787 -5.519199030005765 24.997290085978047 0.8971009779739698 1.1314429332024605 0.385993750467006 0.11889598984903331 151.93307645904363 1032121.6091116078 0.03479179105730825 0.061990181832698145 3.025526561360983e-06 5.519199030005765 0.23434195522849066 ISKPGAVST(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 1 ISKPGAVSTPVK 12 1 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 ISKPGAVS(0.021)T(0.979)PVK 115.04 0.00053427 63484000.0 114380.0 110920.0 120650.0 108280.0 119520.0 155710.0 129290.0 142270.0 135120.0 143240.0 True False 150750.460748204 146772.7208411785 119050.10216869041 83317.71890932352 102926.71106537321 145973.42908489978 140796.55953208255 120285.44053936373 142262.16734705272 138225.21119886308 1.0906147976964997 1.061837558924169 0.8612763267723595 0.6027678900736512 0.744630521253418 1.0560550265673996 1.0186026001401445 0.8702134689909093 1.0292056428286567 1.0 17.076661250469655 -8.269865182645916 23.740979688866926 1.014602854702993 0.9087721497550366 0.07037251583125415 0.1466291031717007 1109.7401935200505 3126785.299880207 0.1489245004365387 0.041165560517781245 5.37198532185978e-09 8.269865182645916 -0.10583070494795643 ISKPGAVST(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISKPGAVSTPVK 12 1 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 ISKPGAVS(0.176)T(0.824)PVK 85.734 0.0068512 50054000.0 156930.0 207010.0 172860.0 155670.0 184000.0 131680.0 167520.0 109810.0 104850.0 106990.0 True False 183495.14949121684 227560.58471857058 176981.63797520092 146948.31458894923 147946.5208550518 124774.46899060837 151651.29286022874 106927.60385331235 106383.23289328812 126386.44006762601 1.4518578843824819 1.8005142371033553 1.400321410117278 1.1626905110257169 1.1705885597844954 0.987245696008566 1.1999016095325115 0.8460369941276789 0.8417297997820438 1.0 16.947482160288878 -5.842814733165539 0.9066707807070047 0.9616035612787522 1.6836753216132512 0.7737677946416665 0.13481752660713858 0.3223277895002851 0.5057487916885237 0.058822825211785786 0.1670786915976367 1.4361019332315663e-06 5.842814733165539 0.7220717603344989 ISKPGAVST(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 2 ISKPGAVSTPVK 12 1 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 ISKPGAVS(0.209)T(0.791)PVK;ISKPGAVS(0.264)T(0.736)PVK 101.01 0.0020578000000000003 117544000.0 258100.0 382340.0 362030.0 314750.0 373610.0 303710.0 299440.0 270720.0 278256.0 270900.0 True False 254419.44667025623 381454.71522089874 332265.29087621387 337897.7649752198 351634.99434552126 290721.031282589 314943.53802882746 283298.6395119498 246915.8791144197 317724.7040484398 0.8007543745527193 1.2005824865375994 1.0457647348238845 1.0634922644343843 1.1067285290221296 0.9150092126241028 0.9912466170109696 0.8916481340675307 0.777137805050171 1.0 18.277417742714732 -7.212297394093987 1.4322972799746503 0.8848023766382539 1.0503309053843628 0.22100582522240286 0.11228380810771864 0.5546917967775326 2.2337451574556764 0.0629133359221868 0.038655675500576664 6.133418600292194e-08 7.212297394093987 0.1655285287461089 ISLEQPPNGS(ph)DTPNPEK ddPTM_PC-9_AZD4547_30min_R2 2 ISLEQPPNGSDTPNPEK 17 0 Q9UHI6;E9PJ60 Q9UHI6 DDX20 Probable ATP-dependent RNA helicase DDX20 1 ISLEQPPNGS(0.911)DT(0.089)PNPEK;ISLEQPPNGS(0.662)DT(0.338)PNPEK 131.25 2.4718000000000003e-05 3934500.0 26426.8 26967.5 33289.0 35427.0 36214.0 36041.0 33996.0 43106.0 35406.0 36392.0 True False 34829.972688412694 35684.216996794836 32847.56610935379 27259.852491693815 31186.3111991418 33787.35057253143 37021.57814102146 36444.958177337605 37277.4888772184 35117.92715686272 0.9918003569184534 1.0161253777138566 0.9353503685633889 0.7762375145301453 0.888045329664265 0.9621111867341159 1.054207384611729 1.0377878516162806 1.061494566883446 1.0 15.09992007155342 -7.09936903178494 3.7826887027387044 1.0410642126589025 0.9196807899124166 0.4380123586361535 0.06228474446021406 0.2575859251382636 6.676904926931303 0.028266650774075808 0.021774553537199204 7.954831195983351e-08 7.09936903178494 -0.12138342274648584 ISLEQPPNGS(ph)DTPNPEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISLEQPPNGSDTPNPEK 17 0 Q9UHI6;E9PJ60 Q9UHI6 DDX20 Probable ATP-dependent RNA helicase DDX20 1 ISLEQPPNGS(0.954)DT(0.046)PNPEK 115.66 0.0014044 0.0 8218.0 10600.0 9635.4 7546.3 8867.0 6213.8 7276.3 9254.2 6642.9 5069.2 True False 9609.145087101375 11652.297947040497 9865.144478457994 7123.5052764347 7129.575002292089 5887.937389230277 6587.036188149954 9011.287055635406 6740.03984536789 5988.20583223488 1.6046784890684211 1.945874653191689 1.6474290889189738 1.1895892486007134 1.19060286203142 0.9832556786099683 1.1000016319899248 1.5048392303295746 1.1255524666646963 1.0 12.547908096579606 -5.705947439972103 3.7109082020548887 1.1655585037817557 1.7800024345971408 0.7448345803478369 0.15561639724018525 0.11110630485371192 3.095432886484005 0.044605491019959524 0.07891246788123128 1.9681244654648402e-06 5.705947439972103 0.6144439308153851 ISLEQPPNGS(ph)DTPNPEK ddPTM_PC-9_Lapatinib_30min_R1 2 ISLEQPPNGSDTPNPEK 17 0 Q9UHI6;E9PJ60 Q9UHI6 DDX20 Probable ATP-dependent RNA helicase DDX20 1 ISLEQPPNGS(0.944)DT(0.056)PNPEK;ISLEQPPNGS(0.997)DT(0.003)PNPEK 173.34 9.6798e-25 3726400.0 38464.0 50763.0 58064.0 57517.0 64365.0 58649.0 54127.0 56274.0 58496.0 49138.0 True False 37915.4963065663 50645.461392369434 53290.20205352169 61746.99205108735 60579.17724645886 56140.71898749652 56929.43121455497 58888.69547833717 51907.56448981196 57631.43782773066 0.6578960674189949 0.8787818472229793 0.9246724368185016 1.0714116180071496 1.0511481151579014 0.9741335823567315 0.9878190335060857 1.0218154829724124 0.9006814066477353 1.0 15.814568393045699 -4.682755065347107 1.4246527141093508 1.0001276104870354 0.4607552408219336 0.8257532780156467 0.04722894022416287 0.6033335590700091 0.94402368265528 0.013981415581000361 0.4987418425518812 2.0760840632101497e-05 4.682755065347107 -0.5393723696651018 ISLGLPVGAVINCADNTGAK ddPTM_PC-9_Lapatinib_30min_R1 2 ISLGLPVGAVINCADNTGAK 20 0 P62829;C9JD32;J3KT29;B9ZVP7 P62829 RPL23 60S ribosomal protein L23 0 ; 196.45 7.9069e-15 3607700.0 35576.0 34814.4 37224.0 32600.0 35059.0 37464.0 38771.0 36845.0 30185.5 36721.0 False True 35068.67971616064 34733.789395790365 34163.58640879529 34997.51275041201 32996.898548646015 35861.75205284948 40778.37267204005 38556.953209285515 26785.6911225933 43068.17592234314 0.8142596932684933 0.8064838747389573 0.7932443312759785 0.812607267452342 0.7661550052210988 0.8326740402823729 0.9468330570945965 0.8952539173892138 0.6219369766411972 1.0 15.394334601584825 -6.997763178424101 24.650904188688923 0.8619166305555789 0.7994707419093205 0.10407392446149988 0.09304224702715362 155.2863893476577 1711306.167351057 0.03234812959440817 0.028349795866505115 1.0051637584981046e-07 6.997763178424101 -0.06244588864625833 ISLPGQMAGT(ph)PITPLK ddPTM_PC-9_AZD4547_30min_R2 3 ISLPGQMAGTPITPLK 16 0 Q9H8Y8-2;Q9H8Y8;Q9H8Y8-3 Q9H8Y8-2 GORASP2 Golgi reassembly-stacking protein 2 1 ISLPGQMAGT(1)PITPLK;ISLPGQMAGT(0.941)PIT(0.059)PLK;ISLPGQMAGT(0.998)PIT(0.002)PLK 145.82 0.00011347 42012000.0 158092.0 208724.0 197973.0 259180.0 334639.0 464823.0 321492.0 451130.0 393238.0 345896.0 True False 208361.96748212224 276189.9511797165 195347.74866673976 199430.05529108303 288180.1511396044 435757.54432939715 350104.165187472 381418.22443609516 414023.7578687114 333786.28632254887 0.624237651515662 0.8274454718395018 0.5852479765390022 0.5974782771583584 0.8633672590764446 1.3054986444479328 1.0488872057767964 1.1427019025806169 1.2403857642869915 1.0 18.348565156935784 -6.555173053644137 4.639900456265384 1.1486566166242984 0.6702911283068345 0.834185297024992 0.10294022623108041 0.075530549436092 3.88512471054139 0.033776276165746535 0.03464941694850073 2.7850112020217104e-07 6.555173053644137 -0.47836548831746395 ISLPGQMAGT(ph)PITPLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISLPGQMAGTPITPLK 16 0 Q9H8Y8-2;Q9H8Y8;Q9H8Y8-3 Q9H8Y8-2 GORASP2 Golgi reassembly-stacking protein 2 1 IS(0.001)LPGQMAGT(0.945)PIT(0.054)PLK 109.67 0.0025106 21413000.0 47875.0 70558.0 50525.0 66195.0 96363.0 66789.0 113440.0 60621.0 70173.0 88705.0 True False 55979.29192564839 77562.531938423 51729.70761712956 62486.308757085484 77481.36189758351 63286.46726468518 102694.14196552221 59029.762983258785 71199.14737072696 104786.51431160627 0.5342222927578388 0.7401957441562886 0.49366760557851597 0.5963201387849241 0.7394211211871716 0.6039562216612019 0.9800320455372538 0.5633335870656075 0.6794686113806618 1.0 16.677093533032973 -6.598882459791043 1.5114997731827147 0.7621080348010171 0.5966937054702599 0.2522577501319354 0.144756125947325 0.6573039754558408 3.0983247318285705 0.05912069091485437 0.061326927704168296 2.518358420004489e-07 6.598882459791043 -0.16541432933075717 ISLPGQMAGT(ph)PITPLK ddPTM_PC-9_Lapatinib_30min_R1 3 ISLPGQMAGTPITPLK 16 0 Q9H8Y8-2;Q9H8Y8;Q9H8Y8-3 Q9H8Y8-2 GORASP2 Golgi reassembly-stacking protein 2 1 ISLPGQMAGT(1)PITPLK;IS(0.001)LPGQMAGT(0.999)PITPLK;ISLPGQMAGT(0.971)PIT(0.029)PLK 138.98 6.5541e-05 40701000.0 96703.0 160645.0 171419.0 125146.0 368701.0 350488.0 412187.0 369608.0 323903.0 311425.0 True False 95323.99748684163 160273.03637249934 157325.59151647534 134349.6543148179 347014.732074056 335498.4452674327 433528.0260135194 386781.3370003423 287421.6332902003 365254.3963022721 0.26097974029025717 0.43879837722709525 0.4307288101366973 0.3678248795221473 0.9500631219969723 0.9185336266008572 1.1869207609885861 1.0589368421461935 0.7869080733865828 1.0 18.478542112244 -6.283156771151031 5.019222894062234 0.9976592182058549 0.3804544768641814 0.888387122950601 0.1057317867292975 0.060239444052376766 4.432090940794991 0.033926600749010855 0.04024454884569304 5.210066047568217e-07 6.283156771151031 -0.6172047413416735 down ISLPGQMAGTPIT(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 1 ISLPGQMAGTPITPLK 16 0 Q9H8Y8-2;Q9H8Y8;Q9H8Y8-3 Q9H8Y8-2 GORASP2 Golgi reassembly-stacking protein 2 1 ISLPGQMAGT(0.365)PIT(0.635)PLK 138.66 3.9827e-05 15194000.0 20161.0 31513.0 33911.0 23202.0 56404.0 63858.0 61715.0 62685.0 53693.0 50064.0 True False 19873.500442925415 31440.03358465293 31122.96848024549 24908.352479603054 53086.42761453064 61126.94220026857 64910.30072618584 65597.57394284329 47645.52892764414 58717.49569391322 0.3384596057455077 0.5354457511019509 0.5300459107194478 0.42420665570355903 0.9040989740308986 1.0410345584034355 1.1054677989768997 1.1171725423167744 0.8114366657599666 1.0 15.841502817978915 -6.356992999329756 3.612068358016747 1.0241520883675892 0.46583313133030396 0.8852119664892444 0.09561039762836082 0.07699679449807284 1.873853509980474 0.03108120408546795 0.035960648477147666 4.3954870074707293e-07 6.356992999329756 -0.5583189570372853 down ISMPDIDLNLT(ph)GPK ddPTM_PC-9_AZD4547_30min_R2 2 ISMPDIDLNLTGPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ISMPDIDLNLT(1)GPK;ISMPDIDLNLT(1)GPK 126.48 0.00012130000000000001 8110000.0 36023.0 47784.0 45730.0 56538.0 55257.0 49841.0 48023.0 58886.0 47215.0 53312.0 True False 47477.564675053014 63229.243532950546 45123.5903205488 43504.03760339246 47585.51935524872 46724.4343909863 52296.95396712188 49786.52176566376 49710.68850866708 51445.56310690991 0.922869958219508 1.2290514422313303 0.8771133523560951 0.8456324506155365 0.9249683836944389 0.9082305950055878 1.016549354478688 0.9677515175060196 0.9662774689697232 1.0 15.650759037627314 -5.28998797203678 24.953573484201836 0.9350964867621708 1.0759608376271463 0.29585935487536574 0.084823010392423 708.1820779377498 619002.2338435436 0.021638800324362484 0.0450573956765206 5.1287558809375045e-06 5.28998797203678 0.1408643508649755 ISMPDIDLNLT(ph)GPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISMPDIDLNLTGPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ISMPDIDLNLT(1)GPK 131.24 6.488e-05 4315700.0 78688.0 73920.0 68241.0 73783.0 78530.0 63570.0 73676.0 64425.0 51721.0 45663.0 True False 92008.3242411578 81258.2890797392 69868.12424543369 69649.17771771332 63142.61023232194 60236.277291410785 66696.87591195208 62733.91201392995 52477.321778481244 53941.340431890916 1.7057107499457154 1.5064195370217033 1.295261179756049 1.2912022052113428 1.1705791833639918 1.1166996742965292 1.2364704951328926 1.163002467340258 0.9728590605704688 1.0 15.719103752261523 -1.52287874528034 0.34510443279056474 1.0561819950785307 8.579594877438245 0.9101373821841093 0.0634587639726086 17.312406685490668 0.24454915513066525 0.056643607717899266 84.34772996604937 0.02999999999999983 1.52287874528034 7.523412882359715 ISMPDIDLNLT(ph)GPK ddPTM_PC-9_Lapatinib_30min_R1 1 ISMPDIDLNLTGPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ISMPDIDLNLT(1)GPK 95.98100000000001 0.011701000000000001 2423500.0 22640.0 16761.0 18118.0 15520.0 13636.0 14653.0 13287.0 12566.0 13375.0 12023.0 True False 22317.149448332475 16722.19093429278 16628.407977502502 16661.392573202284 12833.95728940749 14026.325347811331 13974.935846209692 13149.86223443837 11868.56665500606 14101.159530359511 1.5826464057997573 1.1858734665252344 1.1792227399244635 1.181561880590787 0.9101348908064077 0.9946930475903727 0.9910487017838453 0.9325376545189055 0.8416730999641041 1.0 13.783526179047195 -1.522878745281273 0.43937773464172636 0.9250488241937121 14.037835701461397 0.8619814287528267 0.07550046940559334 28.99549682877964 0.35746139941441724 0.04858761560497787 338.7388777202799 0.029999999999935377 1.522878745281273 13.112786877267684 ISMPDLDLHLKS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 ISMPDLDLHLKSPK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ISMPDLDLHLKS(1)PK;ISMPDLDLHLKS(1)PK;ISMPDLDLHLKS(1)PK 58.04 0.02733 195018000.0 127890.0 133134.0 140137.0 178228.0 157193.0 155723.0 159359.0 162662.0 159105.0 178375.0 True False 168556.35972274753 176166.96192273241 138278.69181611083 137140.28819515082 135369.46529868813 145985.61619284473 173541.64228071042 137526.32550090685 167514.96548070497 172130.14554312482 0.9792378853274023 1.0234521173898399 0.8033380287909362 0.7967244073513678 0.7864367096858882 0.8481118500900242 1.0082001716383373 0.798967113325606 0.973187845465084 1.0 17.39314025639962 -9.495967482161776 13.19105568812368 0.9999999823670193 0.8858293760400745 0.11122885758561862 0.09157639801182002 0.0 0.0 0.09297345179672549 0.0225493742433042 3.191776830730019e-10 9.495967482161776 -0.11417060632694476 ISMPDLDLHLKS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISMPDLDLHLKSPK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ISMPDLDLHLKS(1)PK 53.001000000000005 0.040934 70594000.0 21623.0 24823.0 20111.0 29219.0 39232.0 37162.0 53877.0 58785.0 45107.0 43206.0 True False 25283.34682628294 27287.263390508127 20590.522511392224 27581.954159276123 31544.771229268452 35213.1593000379 48773.38052429875 57241.95603785602 45766.6045409399 51038.9057814922 0.49537399830878087 0.5346365282071364 0.4034279770719299 0.5404103739480625 0.6180534387691999 0.6899277866730236 0.9556117980488724 1.1215357218456117 0.8967003473169257 1.0 15.639309779174631 -7.035632315103035 1.501159307808162 1.0212187796557333 0.49577520401290276 0.9174021324597208 0.06768468594074732 0.1022579081417884 0.4645250534033099 0.03480316242260795 0.025067107116554983 9.212291780446757e-08 7.035632315103035 -0.5254435756428305 down ISMPDLDLHLKS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 5 ISMPDLDLHLKSPK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ISMPDLDLHLKS(1)PK;ISMPDLDLHLKS(1)PK;ISMPDLDLHLKS(1)PK;ISMPDLDLHLKS(1)PK;ISMPDLDLHLKS(1)PK 77.279 0.018591 34590000.0 132252.0 123242.0 108705.0 115570.0 148455.0 165210.0 176773.0 178148.0 180124.0 135415.0 True False 130366.06222795365 122956.64072096601 99767.69451343488 124069.4033302185 139723.1687737597 158144.3534233201 185925.4409830682 186425.40644124785 159836.53833019175 158821.30232085436 0.8208348648633116 0.7741822974890752 0.6281757740021672 0.7811886788308202 0.8797508062960461 0.9957376693954652 1.1706580809132106 1.1738060557180614 1.0063923163612296 1.0 17.277044905126175 -6.671759077995461 1.8524176914774875 1.10058712076691 0.7435720412456789 0.8123388171719218 0.07299095906452203 0.13769159526272606 0.9721963760855827 0.02992310170768222 0.029226558852072274 2.129319944624871e-07 6.671759077995461 -0.3570150795212311 ISMPDVDLHLK ddPTM_PC-9_AZD4547_30min_R2 3 ISMPDVDLHLK 11 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ;; 117.09 0.0010041 7351300.0 59500.0 71646.0 82059.0 90527.0 89275.0 78019.0 78163.0 95325.0 82287.0 78199.0 False True 78419.76232311736 94804.16838610776 80970.84404360184 69657.39877820776 76880.70724867118 73140.4595965243 85119.35557820524 80594.71160058258 86636.52282776 75461.2768119231 1.0392053465854796 1.2563287078006136 1.0730118474593344 0.9230879958713034 1.0188100506208744 0.9692449251662795 1.1279872164150306 1.068027404326246 1.148092458648555 1.0 16.203448890440193 -5.509383487822804 24.725727803061925 1.0363815234944374 1.1519928578768202 0.23099111447256304 0.08028356507519772 728.7838462274111 1335259.5380474634 0.021470797934359197 0.04178981585116332 3.094685443836022e-06 5.509383487822804 0.1156113343823828 ISMPDVDLHLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISMPDVDLHLK 11 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 61.435 0.040263 5564900.0 59665.0 51588.0 51160.0 47717.0 62297.0 48660.0 59849.0 47120.0 52294.0 46170.0 False True 69765.10606253384 56709.31570678541 52379.84842538043 45043.571190601266 50090.35005275636 46108.18393896569 54179.66945076297 45883.14992776688 53058.7008194717 54540.25551848111 1.2791488671866187 1.039769894139372 0.9603887610616597 0.8258775240856385 0.9184106230632364 0.8453972850079847 0.9933886252587145 0.8412712681960071 0.9728355746608597 1.0 15.735033838775527 -4.735501214693501 1.6359904111496166 0.9084309538863363 1.4421809988530554 0.7666468586561039 0.060617172131293445 0.4820594921582656 1.1561174899340347 0.015863282710663857 0.42642227094322505 1.8386488112753477e-05 4.735501214693501 0.5337500449667191 ISMPDVDLHLK ddPTM_PC-9_Lapatinib_30min_R1 1 ISMPDVDLHLK 11 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 71.555 0.019972999999999998 3542000.0 24150.0 25691.0 32486.0 28291.0 35403.0 36111.0 29414.0 24321.0 30544.0 29905.0 False True 23805.61657143239 25631.51406795035 29815.12647958639 30371.61451600939 33320.665144976025 34566.61670885246 30936.912996192652 25451.042448175664 27103.813077420946 35074.03940409224 0.6787246914210538 0.730783066434025 0.8500625244809336 0.8659286193441923 0.9500093434087994 0.9855328127623482 0.8820459097899944 0.7256376191789925 0.7727599540262428 1.0 15.098115971892705 -5.201102810126479 2.1735643297779323 0.8786327560963392 0.6775873366709488 0.4343637211669066 0.08127743357033297 0.38428723102919476 3.2694629898604957 0.024944145098627 0.10461185037150456 6.293571780849206e-06 5.201102810126479 -0.20104541942539034 ISMQDVDLS(ph)LGSPK ddPTM_PC-9_AZD4547_30min_R2 2 ISMQDVDLSLGSPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ISMQDVDLS(0.994)LGS(0.006)PK;ISMQDVDLS(0.889)LGS(0.111)PK 127.29 2.5767e-05 119067000.0 225228.0 217524.0 203361.0 228834.0 229208.0 197441.0 204634.0 188529.0 177313.0 197127.0 True False 296845.8189665727 287834.37908633763 200664.30026628327 176079.8567500568 197386.42561807315 185094.98305793863 222846.0295714143 159396.17501543372 186685.40318833626 190225.64373078942 1.5604931761286294 1.513120804541399 1.0548751279310524 0.9256368032022434 1.0376436202125188 0.973028554025493 1.1714825887869766 0.8379321099368385 0.9813892571315812 1.0 17.537352219002607 -5.273022166337673 3.846153775265885 0.9914511957044602 1.553928531368625 0.8813254231998195 0.07951122930318744 0.06286108161613806 2.127939865349247 0.020861194956195907 0.053995280221871014 5.333076748339288e-06 5.273022166337673 0.5624773356641649 ISMQDVDLS(ph)LGSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISMQDVDLSLGSPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ISMQDVDLS(0.999)LGS(0.001)PK 128.71 2.188e-05 38658000.0 32002.0 31236.0 24332.0 29368.0 44597.0 41492.0 46931.0 49333.0 36761.0 43335.0 True False 37419.30653168875 34336.90364846764 24912.167159623863 27722.606172340635 35858.53799224318 39316.08647750854 42485.355928983874 48038.06102263418 37298.56008002062 51191.29246032876 0.7309701461569317 0.6707567243995136 0.48664852873034636 0.5415492526160492 0.7004812003922765 0.7680229310087641 0.8299332540179242 0.9384029727294303 0.7286114158755718 1.0 15.643610811011932 -6.852728962892154 1.7090013585678103 0.8712138448597496 0.6055651111635325 0.6303607250469832 0.09139375313912088 0.24693844869652135 1.485954946896537 0.04145868976964091 0.035235423319808334 1.4036894542045616e-07 6.852728962892154 -0.2656487336962171 ISMQDVDLS(ph)LGSPK ddPTM_PC-9_Lapatinib_30min_R1 1 ISMQDVDLSLGSPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ISMQDVDLS(0.661)LGS(0.339)PK 109.1 0.00054781 22098000.0 56547.0 44674.0 39175.0 40617.0 46916.0 57149.0 61889.0 53697.0 56688.0 49969.0 True False 55740.62941055024 44570.56009776236 35954.182719873104 43604.10967434 44156.493120404906 54704.87049082576 65093.30959479728 56191.958650536115 50303.200488895964 58606.07507049279 0.9511066786762988 0.7605109204831039 0.613489005647052 0.7440203020231594 0.753445663564612 0.9334334439736056 1.1106921853494112 0.9588077444692735 0.8583274076687454 1.0 15.838762600848803 -6.822590622773296 4.327049008022478 0.9834316902482488 0.753927444351277 0.541878715533201 0.09588154629454834 0.16855195393520814 6.3090583397641735 0.03619463655014854 0.03245227993822328 1.5045595346515203e-07 6.822590622773296 -0.22950424589697183 ISMQDVDLSLGS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 6 ISMQDVDLSLGSPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ISMQDVDLS(0.383)LGS(0.617)PK;ISMQDVDLSLGS(1)PK;ISMQDVDLS(0.036)LGS(0.964)PK;ISMQDVDLS(0.026)LGS(0.974)PK;ISMQDVDLSLGS(1)PK;ISMQDVDLS(0.003)LGS(0.997)PK 202.18 1.3994e-08 97267200.0 683887.0 672786.0 578664.0 723635.0 697044.0 687625.0 602790.0 585699.0 616959.0 665094.0 True False 901348.8402667191 890250.9174526979 570990.5372676597 556812.1307993019 600271.472455253 644627.7000481914 656437.1422410369 495192.67757408274 649570.1931932388 641809.2614988593 1.4043874003340806 1.3870957788512377 0.8896576779434251 0.8675663693274572 0.9352801657199519 1.0043913958841135 1.0227916323737931 0.771557388277051 1.0120922712711482 1.0 19.29178508272601 -5.257542288666906 24.90588629729854 0.9325570539216331 1.3957416553471695 0.8561292270482004 0.07504586172402614 101.57584244599643 649153.3833286138 0.019303674303008857 0.04725595210739707 5.526595910615673e-06 5.257542288666906 0.4631846014255364 ISMQDVDLSLGS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ISMQDVDLSLGSPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ISMQDVDLS(0.09)LGS(0.91)PK;ISMQDVDLSLGS(1)PK 106.19 0.00079177 49418000.0 82467.0 81078.0 58678.0 76667.0 113011.0 95094.0 119032.0 114595.0 93183.0 93298.0 True False 96427.03430250562 89126.88801416491 60077.1060575542 72371.59654776778 90867.30580625136 90107.10323658053 107756.42724294838 111587.00267343922 94545.62509008359 110212.18885343839 0.8749216879335874 0.8086844925354583 0.5451040096612683 0.6566569206243466 0.8244760107894045 0.8175783837884404 0.9777178764341963 1.0124742447664212 0.8578508971980549 1.0 16.749924261195098 -6.920420051068653 1.7866680941574715 0.9629606097751676 0.7214237561848912 0.5474489475536675 0.09468250705747203 0.2867889672869121 1.8686113002551659 0.04554205707559573 0.03692258503002669 1.201102162621219e-07 6.920420051068653 -0.24153685359027643 ISMQDVDLSLGS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 7 ISMQDVDLSLGSPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 ISMQDVDLS(0.003)LGS(0.997)PK;ISMQDVDLS(0.168)LGS(0.832)PK;ISMQDVDLS(0.019)LGS(0.981)PK;ISMQDVDLSLGS(1)PK;ISMQDVDLS(0.007)LGS(0.993)PK;ISMQDVDLSLGS(1)PK;ISMQDVDLSLGS(1)PK 197.51 9.404600000000001e-08 87218000.0 407917.80000000005 401572.4 320527.7 347946.9 423360.2 489317.5 504306.2 476429.1 486587.6 480121.9 True False 402100.81736903783 400642.58378033433 294175.14977870276 373536.07574283297 398458.98539417743 468390.5311798047 530416.707446812 498565.73527594056 431782.9804934157 563110.330692783 0.7140711072985315 0.7114815018354077 0.5224112109908997 0.6633443845423316 0.7076037566278736 0.8317917566945602 0.9419409990121319 0.8853784207129808 0.7667822040526268 1.0 19.10305809292138 -6.745820268327132 2.408982744131433 0.8896140241244612 0.6497109059688353 0.6996315113208462 0.07404376019220854 0.17103751778802362 2.035914799856869 0.02877217889514833 0.02685904606834415 1.795476526517518e-07 6.745820268327132 -0.23990311815562593 ISMS(ph)EVDLNVAAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ISMSEVDLNVAAPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 IS(0.171)MS(0.829)EVDLNVAAPK;IS(0.375)MS(0.625)EVDLNVAAPK;IS(0.005)MS(0.995)EVDLNVAAPK;IS(0.001)MS(0.999)EVDLNVAAPK 155.57 0.000291 10438900.0 82661.9 86405.0 85137.0 98063.0 132315.0 97958.0 114005.0 99107.0 93674.0 88308.0 True False 96654.92702305516 94982.71736924836 87166.98896387067 92568.84803453577 106388.82558117516 92820.91003479653 103205.62107527639 96505.54626254624 95043.80503620276 104317.54135425655 0.9265452939963417 0.9105152991163045 0.8355928239130601 0.8873756688741075 1.0198555698306255 0.8897919643215315 0.9893410037799477 0.9251133127727655 0.9111008925472974 1.0 16.67062224683871 -6.110895025070075 24.544597504213314 0.9507776778489438 0.887568458272699 0.3454946461701295 0.04402408646388739 25.015811541329576 5508.881493466244 0.012674508048606495 0.01636273326774043 7.746490184619649e-07 6.110895025070075 -0.06320921957624481 ISMS(ph)EVDLNVAAPK ddPTM_PC-9_Lapatinib_30min_R1 2 ISMSEVDLNVAAPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 IS(0.404)MS(0.596)EVDLNVAAPK;IS(0.266)MS(0.734)EVDLNVAAPK 192.4 6.6666e-07 4185600.0 24273.0 24849.0 26580.0 20839.7 35812.0 35213.0 26844.0 27700.0 36218.0 29041.0 True False 23926.86256887696 24791.46366721802 24394.69500176713 22372.32105720127 33705.60856910096 33707.0220755122 28233.85097129922 28987.043123821622 32138.747447552098 34060.69815529987 0.7024771617945806 0.7278612891075003 0.7162124185047363 0.6568368315644793 0.9895748001235947 0.9896162997547765 0.8289275470093678 0.8510407799527508 0.9435727741403118 1.0 15.055820386347058 -6.258487093764519 24.997143624389285 0.9238890636041894 0.7038740518468221 0.8015798165573096 0.056640673741739825 127.55165158667278 1079985.9681582223 0.0182962954532164 0.02259123783778702 5.514585902221759e-07 6.258487093764519 -0.22001501175736737 ISNLS(ph)PEEEQGLWK ddPTM_PC-9_AZD4547_30min_R2 3 ISNLSPEEEQGLWK 14 0 F5GX09;Q5HYJ3-3;Q5HYJ3-2;Q5HYJ3 F5GX09 FAM76B Protein FAM76B 1 IS(0.001)NLS(0.999)PEEEQGLWK;ISNLS(1)PEEEQGLWK;ISNLS(1)PEEEQGLWK 179.81 5.4583e-05 22651500.0 83675.0 77543.0 100843.0 131333.0 111074.0 107293.0 99853.0 106538.0 99173.0 110410.0 True False 110281.90945187991 102607.25831398772 99505.7559303544 101056.20592462299 95653.29237680098 100583.95174880313 108739.72355910766 90075.00009968894 104415.08231430774 106544.57950618837 1.0350776169281748 0.9630453167073417 0.9339354136225659 0.9484875382022921 0.8977771822849533 0.944055082060378 1.0206030570780167 0.8454207667547946 0.9800130874630094 1.0 16.701097671795218 -4.770174653381219 2.7912022600753206 0.941770377781225 1.0539710898560752 0.23469212372315085 0.04734187095662761 0.6134676117374523 6.391531145762519 0.011578695729072459 0.1624170862480937 1.6975608338303654e-05 4.770174653381219 0.11220071207485027 ISNLS(ph)PEEEQGLWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ISNLSPEEEQGLWK 14 0 F5GX09;Q5HYJ3-3;Q5HYJ3-2;Q5HYJ3 F5GX09 FAM76B Protein FAM76B 1 ISNLS(1)PEEEQGLWK;IS(0.091)NLS(0.909)PEEEQGLWK;ISNLS(1)PEEEQGLWK 172.32 3.5674e-19 12672400.0 46941.2 49905.9 47466.0 57629.0 62793.0 53908.0 59891.0 52721.0 45738.0 42130.7 True False 54887.41802903909 54860.22793539701 48597.769455807436 54400.23396573885 50489.16241332211 51080.96958038972 54217.69090670926 51337.12961251691 46406.831722205156 49768.662403562324 1.1028509784725573 1.102304648868165 0.9764732887884269 1.0930620060595602 1.0144769815977255 1.0263681423902093 1.0893941747333054 1.0315151569924916 0.9324508532277425 1.0 15.602949992811533 -1.5228787452803376 0.19553076727807767 0.989904993034094 1.4860951100020987 0.31286707538976954 0.046229329517145194 74.24588557677845 0.884212977913949 0.09086599388794772 11.209567766553707 0.029999999999999995 1.5228787452803376 0.49619011696800475 ISNLS(ph)PEEEQGLWK ddPTM_PC-9_Lapatinib_30min_R1 3 ISNLSPEEEQGLWK 14 0 F5GX09;Q5HYJ3-3;Q5HYJ3-2;Q5HYJ3 F5GX09 FAM76B Protein FAM76B 1 IS(0.003)NLS(0.997)PEEEQGLWK;IS(0.004)NLS(0.996)PEEEQGLWK;IS(0.044)NLS(0.956)PEEEQGLWK 210.67 2.8926999999999997e-11 18454700.0 136225.0 101164.0 122084.0 109544.0 118507.0 108239.0 104692.0 108389.0 125834.0 96697.0 True False 134282.4065193945 100929.76097349756 112046.72477786824 117600.23118807162 111536.6512537264 103609.87028743266 110112.43949810971 113425.1486334986 111661.24982923605 113410.94760934633 1.1840338992840593 0.8899472502527597 0.9879709775798957 1.0369389698881242 0.9834734089157239 0.9135790897746986 0.9709154347021365 1.0001252174014204 0.9845720557230748 1.0 16.791200385434635 -4.746471338250208 24.996899945325364 0.974861576897511 1.1840344547224269 0.706747289473302 0.040553276653737716 471.06354395934915 786640.9589823266 0.010367950548036325 0.2361008527570655 1.7927868654345634e-05 4.746471338250208 0.2091728778249159 ISNYGWDQSDK ddPTM_PC-9_Lapatinib_30min_R1 2 ISNYGWDQSDK 11 0 Q9HB71;Q9HB71-3 Q9HB71 CACYBP Calcyclin-binding protein 0 ; 103.21 0.013812999999999999 8643300.0 28383.0 33294.0 32663.0 31248.0 32233.0 22287.0 33594.0 29099.0 24750.6 29525.0 False True 27978.253215195276 33216.90978857725 29977.574222826148 33546.0821602722 30337.118312516224 21333.836963534508 35333.33294329556 30451.045771122215 21962.92679262752 34628.35691041044 0.8079578620371699 0.959240135895421 0.8656943874173219 0.9687459975956043 0.8760773256150619 0.6160799664485624 1.0203583448879487 0.8793673303617711 0.6342468644830426 1.0 15.079666313909875 -6.533112996951694 24.98880128003798 0.8245578330550555 0.9046670988742286 0.060796311873235864 0.13029160807768492 590.8085975565293 1442556.4830773459 0.04194426628627719 0.04198877343627736 2.930130769705093e-07 6.533112996951694 0.0801092658191731 ISQQHSIYIS(ph)PHK ddPTM_PC-9_AZD4547_30min_R2 2 ISQQHSIYISPHK 13 0 P28749;P28749-2 P28749 RBL1 Retinoblastoma-like protein 1 1 IS(0.034)QQHS(0.003)IYIS(0.963)PHK;ISQQHSIYIS(1)PHK 88.319 0.0037754 13719600.0 28033.0 31667.0 65442.0 81869.0 70006.0 76125.0 56271.0 86548.0 56182.0 69248.0 True False 36946.910877377275 41902.738468063486 64574.19632095677 62995.366913441205 60286.87529152038 71364.89171593316 61279.00998862866 73173.99527518716 59151.665822173796 66823.64859745064 0.5529017294453272 0.6270645100582266 0.9663374819587495 0.9427106755712904 0.9021787429580785 1.0679586226403055 0.9170258026133356 1.095031426912819 0.8851906033821456 1.0 16.028071136088577 -5.221885103817719 3.6340389017045074 0.9755256725302719 0.5674031837524105 0.848287747614583 0.0649158419612818 0.07512036932327482 2.0849920468777703 0.01615189414474699 0.047049965815546026 5.999497769168069e-06 5.221885103817719 -0.4081224887778614 ISQRDPS(ph)PESNK ddPTM_PC-9_AZD4547_30min_R2 2 ISQRDPSPESNK 12 1 Q8NDX5-2;Q8NDX5;Q8NDX5-7;E7EX82;Q8NDX5-3 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 1 ISQRDPS(0.98)PES(0.02)NK;IS(0.035)QRDPS(0.554)PES(0.411)NK 123.1 0.0017882000000000002 18089700.0 52185.0 40478.0 58422.0 70996.0 68534.0 64387.0 50179.0 61175.0 50946.0 64598.0 True False 68778.74448456925 53561.72190956751 57647.286107743304 54628.969077265734 59019.23708295086 60360.870711511365 54644.83379039644 51721.809411651 53638.90155167964 62336.443682100944 1.1033472624027496 0.8592360864010442 0.9247766266829228 0.8763568444144608 0.9467854371663076 0.9683078973727717 0.8766113458295818 0.8297202464006173 0.8604742006974857 1.0 15.927788230557843 -7.281572977406707 22.434486997606758 0.8775114305477503 0.9383447899617146 0.09664291111122758 0.07487199885904255 468.00802057191726 521486.82993207907 0.030243739712602767 0.020435654607649196 5.22910090719022e-08 7.281572977406707 0.06083335941396428 ISQRDPS(ph)PESNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ISQRDPSPESNK 12 1 Q8NDX5-2;Q8NDX5;Q8NDX5-7;E7EX82;Q8NDX5-3 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 1 IS(0.002)QRDPS(0.993)PES(0.005)NK;IS(0.089)QRDPS(0.874)PES(0.037)NK 121.24 0.0022007 16662700.0 63978.0 46899.0 69321.0 84235.0 83426.0 73364.0 81235.0 81487.0 70053.0 67017.0 True False 74808.21177690085 51554.822775306835 70973.87554135655 79515.58604355471 67079.27417855186 69516.66269005915 73539.83270953123 79348.05259261324 71077.39259774452 79166.65159371993 0.9449460128844855 0.6512189379927815 0.8965122827929066 1.004407593889729 0.8473173088436277 0.8781053801140393 0.9289243795093759 1.0022913814749201 0.897819866912028 1.0 16.272605212477124 -5.285750869359704 0.2404287419388536 0.998604149811203 0.7000940451399658 0.20401490458868354 0.08882427484090526 12.473664428647998 0.7740890818307866 0.14791564436539595 1.1014245039739288 5.179038394423416e-06 5.285750869359704 -0.2985101046712373 ISQRDPS(ph)PESNK ddPTM_PC-9_Lapatinib_30min_R1 2 ISQRDPSPESNK 12 1 Q8NDX5-2;Q8NDX5;Q8NDX5-7;E7EX82;Q8NDX5-3 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 1 ISQRDPS(0.659)PES(0.341)NK;ISQRDPS(0.999)PES(0.001)NK 196.37 6.0413e-05 19119600.0 52736.0 58606.0 63515.0 62255.0 61960.0 61635.0 52835.0 48793.0 62738.0 47414.0 True False 51983.974969402036 58470.301407741914 58293.04187499016 66833.44037659196 58315.63461804689 58999.01472820253 55570.537776359524 51060.10090760395 55671.78577957161 55609.446724816284 0.9348047504706364 1.0514454800653312 1.0482579005587604 1.2018360964337171 1.0486641758300923 1.0609530970548862 0.999300317648379 0.91819113324891 1.001121015554494 1.0 15.7630423629547 -7.3664657043618345 3.527987491481368 0.9681619344643817 1.0634080418691538 0.2635574822537712 0.06407069394717599 0.32382863898563147 7.466260690759083 0.030243647332793173 0.019502155911327965 4.30065193946737e-08 7.3664657043618345 0.09524610740477213 ISQS(ph)APVK ddPTM_PC-9_AZD4547_30min_R2 1 ISQSAPVK 8 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8;H0YCI3;P46937-4 P46937-6 YAP1 Transcriptional coactivator YAP1 1 IS(0.006)QS(0.994)APVK 79.07 0.021233000000000002 3377100.0 26460.0 26300.0 29661.0 23189.0 26747.0 29578.0 26702.0 31335.0 25300.0 27034.0 True False 34873.72959780981 34800.960675468785 29267.675759846883 17843.13431647862 23033.640736826797 27728.482984221675 29078.4262713718 26492.895756666694 26637.306349026327 26087.54788850919 1.3367959973413477 1.334006585218291 1.1219021383277823 0.6839713104786672 0.8829362129114653 1.0629010860938475 1.1146477390533132 1.0155379827145827 1.021073596601208 1.0 14.67107372327002 -5.425246056735995 4.123728704747593 0.9715060181632255 1.3298795217775976 0.6216720278833234 0.11313106936379845 0.15979673525077903 4.718220712275966 0.033744015795052366 0.07381044219830726 3.7562452768861913e-06 5.425246056735995 0.35837350361437215 ISQS(ph)APVK ddPTM_PC-9_Lapatinib_30min_R1 2 ISQSAPVK 8 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8;H0YCI3;P46937-4 P46937-6 YAP1 Transcriptional coactivator YAP1 1 IS(0.19)QS(0.81)APVK;IS(0.013)QS(0.987)APVK 80.834 0.018738 5928200.0 40843.0 68341.0 68742.0 60700.0 70316.0 61551.0 68491.0 55686.0 60057.0 48769.0 True False 40260.57133031113 68182.76061335862 63090.29811179361 65164.08048926407 66180.15112657499 58918.60721238896 72037.12885096324 58273.374851737615 53292.74823175319 57198.65666939223 0.7038726724478322 1.19203429911745 1.1030031435258176 1.1392589316548452 1.1570228215165212 1.0300697716196034 1.2594199417538294 1.018789220672738 0.9317132837539323 1.0 15.803693644749558 -4.753221964001359 24.99887737427945 1.1000468174662321 0.7038719417965184 0.6045684254651602 0.09407404633397318 206.45308591783066 628019.1662357313 0.02316093182501814 0.25475143857207205 1.7651354452667193e-05 4.753221964001359 -0.39617487566971377 ISQSALPPLPGS(ph)PAIQINGEWETHK ddPTM_PC-9_AZD4547_30min_R2 1 ISQSALPPLPGSPAIQINGEWETHK 25 0 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 ISQSALPPLPGS(1)PAIQINGEWETHK 97.059 1.2875e-06 6038700.0 31890.0 36401.0 52784.0 51677.0 53904.0 54051.0 42937.0 54692.0 43276.0 55599.0 True False 42030.35664679346 48166.91138964785 52084.049671547094 39763.66605169112 46420.36005076873 50671.18242545699 46758.309820009395 46240.608097131466 45563.48101029498 53652.49593301854 0.7833811999960911 0.8977571416207913 0.9707665741510043 0.7411335737545804 0.8652041110766099 0.9444329018488997 0.8715029749666062 0.8618538111416045 0.8492332037483934 1.0 15.711357666774118 -6.539423790282559 24.925011473532365 0.8957812554517575 0.8533735484442805 0.12024348542846275 0.07098135212714729 689.0723721853919 1038076.3615455946 0.023584898987521436 0.02359098942499363 2.8878604946379437e-07 6.539423790282559 -0.04240770700747698 ISQSALPPLPGS(ph)PAIQINGEWETHK ddPTM_PC-9_Lapatinib_30min_R1 1 ISQSALPPLPGSPAIQINGEWETHK 25 0 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 ISQSALPPLPGS(1)PAIQINGEWETHK 96.12799999999999 1.4038e-06 4032400.0 13922.0 15589.0 15106.0 14148.0 17179.0 21385.0 18540.0 20236.0 22734.0 19153.0 True False 13723.469727017886 15552.904628285296 13864.042990846285 15188.491116344445 16168.564995213492 20470.413400869802 19499.91048308328 21176.238435149975 20173.45752036695 22463.570530231693 0.6109211226482765 0.6923611990958447 0.6171789552416843 0.6761387774888068 0.7197682564957195 0.9112715796146708 0.8680681664938399 0.942692454285074 0.8980521370463931 1.0 14.455299638403396 -6.6662303937619285 1.9988413632069484 0.9249675379870598 0.6473257665538555 0.9169216636098506 0.03963864446966251 0.08323322701031305 0.6824017727831929 0.014497269595255578 0.014215595992492355 2.1566000266392742e-07 6.6662303937619285 -0.27764177143320423 ISQTYQQQYGR ddPTM_PC-9_Lapatinib_30min_R1 2 ISQTYQQQYGR 11 0 P09525-2;P09525;Q6P452;B4E1S2 P09525-2 ANXA4 Annexin A4;Annexin 0 ; 155.26 0.0028747 12953200.0 20024.5 12115.2 22153.0 14610.0 16149.5 14243.9 15673.8 18681.8 15839.8 10279.3 False True 19738.94695795644 12087.147998755678 20331.665853052924 15684.468137531276 15199.618161138616 13634.721601152642 16485.31267150759 19549.824629263945 14055.754923511413 12056.063308693718 1.6372630478576315 1.002578344959382 1.6864265998330987 1.300960996631553 1.2607447200594954 1.1309430990894467 1.3673876994010064 1.621576142119826 1.1658660512653167 1.0 13.557471277485238 -8.519968347438528 24.439447929938765 0.9999999778930936 1.3612539323791575 0.2513154789481068 0.21098629535538385 228.2840216760959 1916956.4975770141 0.19454599285089683 0.050231559358619525 3.0201718307072134e-09 8.519968347438528 0.3612539544860639 ISQVS(ph)SGETEYNPTEAR ddPTM_PC-9_AZD4547_30min_R2 1 ISQVSSGETEYNPTEAR 17 0 H7C3Y7;H0Y764;A0A494C1V1;Q6ZNJ1-2;Q6ZNJ1-3;Q6ZNJ1 H7C3Y7 NBEAL2 Neurobeachin-like protein 2 1 IS(0.003)QVS(0.951)S(0.044)GET(0.002)EYNPTEAR 101.92 0.0075887 0.0 4030.5 5647.4 6604.8 9695.4 7458.9 6165.2 7164.7 7515.5 6176.8 6046.9 True False 5312.115160392003 7472.81160907385 6517.2160365003465 7460.275322436791 6423.360484985877 5779.689069386828 7802.344420136976 6354.152164009209 6503.293037812875 5835.199871533113 0.9103570190126706 1.280643640936755 1.116879657935015 1.278495250665118 1.1007952814644948 0.9904869064696322 1.337116909773825 1.0889347929636126 1.114493621639087 1.0 12.510566357686592 -8.704597769697376 1.843186781798581 1.0008272700437066 1.1470471865604432 0.09489245827154491 0.12568602356708697 1.5515274257398568 9.96849461442133 0.11452556126072652 0.03215819671518795 1.9742503801151492e-09 8.704597769697376 0.1462199165167366 ISREPEPAAGPQAEESATVSAPAPMS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 2 ISREPEPAAGPQAEESATVSAPAPMSPTR 29 1 Q9BWG6-2;Q9BWG6 Q9BWG6-2 SCNM1 Sodium channel modifier 1 1 ISREPEPAAGPQAEESATVSAPAPMS(0.743)PT(0.256)R;ISREPEPAAGPQAEESATVSAPAPMS(0.721)PT(0.279)R 118.84 3.3425e-13 50600000.0 69330.0 50449.0 78254.0 141296.0 116773.0 84522.0 68786.0 85504.0 62155.0 88298.0 True False 91375.49784641528 66755.65266603524 77216.30082974472 108722.39020143871 100561.08459870161 79236.8259785105 74907.82074386116 72291.32148645373 65440.3864080526 85206.71389581963 1.0723978624282833 0.7834553125432804 0.906223198845051 1.2759838424747982 1.1802014184193916 0.9299364141115878 0.8791304971043631 0.8484228317365077 0.7680191315447878 1.0 16.378679492190514 -6.990471026186082 24.335543105465284 0.8674433421434207 1.0365292857594506 0.2564845824352967 0.13720336877650002 234.76852576442536 599558.7760892792 0.05366071522649185 0.04725905591852 1.0221837529791495e-07 6.990471026186082 0.1690859436160299 ISREPEPAAGPQAEESATVSAPAPMS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 4 ISREPEPAAGPQAEESATVSAPAPMSPTR 29 1 Q9BWG6-2;Q9BWG6 Q9BWG6-2 SCNM1 Sodium channel modifier 1 1 ISREPEPAAGPQAEESATVS(0.001)APAPMS(0.733)PT(0.265)R;ISREPEPAAGPQAEESATVSAPAPMS(0.782)PT(0.218)R;ISREPEPAAGPQAEESATVSAPAPMS(0.79)PT(0.21)R;ISREPEPAAGPQAEESATVSAPAPMS(0.956)PT(0.044)R 155.83 3.319e-12 48717300.0 90092.0 57232.0 76305.0 67051.0 69300.0 62059.0 53721.6 43834.0 73694.0 51401.2 True False 88807.27155915047 57099.48282032358 70031.49744581788 71982.15421557912 65223.91024904209 59404.8812365948 56503.04158619239 45870.6876638844 65393.80568777689 60285.82893220618 1.4731035988410772 0.9471460180888319 1.1616577010920939 1.1940145054076627 1.0819111456921158 0.9853871513220455 0.937252461929856 0.7608867370052722 1.0847293111174574 1.0 15.879531294909716 -6.684618888915943 1.9148907593310152 0.9276956894427503 1.1752073991222753 0.3874987666753241 0.1413956233109696 0.35176033541589335 2.6537562716214604 0.054016262770367654 0.05228390871639107 2.0671934064443887e-07 6.684618888915943 0.24751170967952507 ISRPGDSDDSR ddPTM_PC-9_AZD4547_30min_R2 2 ISRPGDSDDSR 11 1 M0R1W6;B4DVF8;M0QYL7;P14866;M0QXS5;A0A3B3ITJ4;P14866-2 M0R1W6;P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 0 ; 84.507 0.015517 77524000.0 97873.0 99025.0 125397.0 187162.0 132818.0 121959.0 115076.0 144271.0 106829.0 125850.0 False True 128994.57811513408 131032.89471058174 123734.15384705566 144014.69252407478 114378.51330556169 114332.88445035796 125317.54106824867 121977.23196776937 112475.7628442739 121444.02980575868 1.0621730711789783 1.0789570711722904 1.0188574444125402 1.185852386110839 0.941820799989116 0.9414450807769266 1.031895444087992 1.0043905176966172 0.9261530848751568 1.0 16.88993204319747 -6.289757928484532 24.99874859747378 0.9757422866271397 1.081095348490665 0.5504631527814617 0.049556654185045006 579.6803789950667 511722.6809217851 0.015260874361884573 0.017306712148656027 5.131473276167407e-07 6.289757928484532 0.10535306186352522 ISRPGDSDDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ISRPGDSDDSR 11 1 M0R1W6;B4DVF8;M0QYL7;P14866;M0QXS5;A0A3B3ITJ4;P14866-2 M0R1W6;P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 0 ;;; 96.171 0.0076673999999999996 104143000.0 182673.0 192365.0 198574.0 232443.0 237547.0 185960.0 197210.0 191336.0 187992.0 144656.0 False True 213595.93094379074 211461.7259040045 203308.75725608872 219419.97230037363 191001.3705954074 176207.9302361296 178528.84112324254 186313.6327372496 190741.0273540773 170880.98770373405 1.2499689626918238 1.237479539096693 1.1897681537783273 1.2840514047167981 1.1177450058198235 1.0311734067316558 1.0447554378183255 1.0903122415249145 1.116221470376656 1.0 17.3826323654745 -6.440909975583489 4.344483663101012 1.0621222336008957 1.2356419515712405 0.8450408404792652 0.03707806069068801 0.08827002442209347 3.02581331117996 0.011946827329903117 0.013394623618872151 3.623180951450233e-07 6.440909975583489 0.1735197179703447 ISRPGDSDDSR ddPTM_PC-9_Lapatinib_30min_R1 4 ISRPGDSDDSR 11 1 M0R1W6;B4DVF8;M0QYL7;P14866;M0QXS5;A0A3B3ITJ4;P14866-2 M0R1W6;P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 0 ;;; 91.70100000000001 0.010433 150502000.0 233825.0 247287.0 293705.0 221110.0 256233.0 265413.0 210405.0 237548.0 266597.0 211648.0 False True 230490.61262174716 246714.42214476826 269557.7086340856 237371.16700133777 241161.8787134604 254061.90469792206 221298.74138042837 248585.34729160974 236570.03846913305 248231.07479676683 0.9285324684286839 0.9938901579778426 1.0859144402238095 0.9562508126578417 0.9715217118199477 1.0234895244518805 0.891502973838434 1.0014271883370482 0.953023462766775 1.0 17.921324204929107 ISS(ph)LLEEQFQQGK ddPTM_PC-9_AZD4547_30min_R2 2 ISSLLEEQFQQGK 13 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 1 IS(0.034)S(0.966)LLEEQFQQGK;IS(0.016)S(0.984)LLEEQFQQGK 165.51 0.00011151 7042200.0 78990.0 69706.0 91013.0 123804.0 112918.0 100631.0 84266.0 102206.0 86881.0 91302.0 True False 104107.17690593329 92237.10132487555 89806.10815316216 95262.90055273277 97241.28480655797 94338.52766195186 91765.5107551274 86412.41116023206 91473.35228892318 88105.54477016599 1.1816189001215474 1.0468932638177 1.0193014342903424 1.081236156035782 1.103690863727404 1.0707445020406532 1.0415406997880652 0.9807828938082085 1.038224694342933 1.0 16.426945195070864 -1.522878745280368 0.16844381695712599 0.9904298012143707 1.5031620134392472 0.4358195546170893 0.04090362861334063 68.82172577780187 0.7400170375894064 0.11700913620887286 8.868563758750822 0.029999999999997896 1.522878745280368 0.5127322122248764 ISS(ph)LLEEQFQQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ISSLLEEQFQQGK 13 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 1 IS(0.017)S(0.983)LLEEQFQQGK;IS(0.05)S(0.95)LLEEQFQQGK;IS(0.042)S(0.958)LLEEQFQQGK 180.48 4.3108e-12 2301000.0 61680.0 63439.0 63408.0 73175.0 82800.0 73405.0 73962.0 72915.0 71642.0 57556.0 True False 72121.20576446984 69736.80466625496 64919.88719617914 69075.24198655086 66575.93438477349 69555.51257788288 66955.78392149112 71001.05850982857 72689.6287166518 67990.44718695471 1.0607549846841968 1.0256853359781302 0.9548383615961167 1.0159551061138525 0.9791954184638364 1.0230189012674777 0.9847822259115526 1.0442799164799654 1.0691153202269086 1.0 16.05304443820436 -7.780340323827666 24.882226354776527 1.0425232425184565 1.0050532363385025 0.16563081949281078 0.03176398926603791 369.1765627593845 485996.5074863957 0.01716818717126435 0.008267631974104975 1.6582869237729973e-08 7.780340323827666 -0.037470006179953996 ISS(ph)LLEEQFQQGK ddPTM_PC-9_Lapatinib_30min_R1 2 ISSLLEEQFQQGK 13 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 1 IS(0.027)S(0.973)LLEEQFQQGK;IS(0.02)S(0.98)LLEEQFQQGK 161.87 5.4468e-05 4992300.0 100047.0 78005.0 91328.0 74167.0 83665.0 94601.0 82574.0 79806.0 100107.0 76171.0 True False 98620.31143362712 77824.38421511298 83819.36437627499 79621.48859385919 78743.98919171884 90555.13575570178 86849.27768231493 83514.0781061265 88831.89548655652 89337.05585852225 1.1039127099711705 0.8711321798913858 0.9382373704928748 0.8912481817170131 0.8814258365131372 1.0136346545727737 0.9721528972238904 0.9348201292684499 0.9943454553420059 1.0 16.446971090332347 -6.772229126884696 24.99501793139662 0.978239517451594 0.9310270259722061 0.10644180144529314 0.06440458922590664 497.9998023613988 1153636.019215519 0.022170198574370296 0.01974325219938911 1.6895493170242823e-07 6.772229126884696 -0.047212491479387886 ISS(ph)PTETER ddPTM_PC-9_AZD4547_30min_R2 3 ISSPTETER 9 0 P31949 P31949 S100A11 Protein S100-A11;Protein S100-A11, N-terminally processed 1 IS(0.031)S(0.968)PT(0.001)ETER;IS(0.039)S(0.959)PT(0.001)ETER;IS(0.15)S(0.848)PT(0.002)ETER 164.66 0.00052661 131255000.0 111777.0 113719.0 153856.0 212285.0 160427.0 151368.0 129779.0 153981.0 125343.0 146180.0 True False 147319.76089396747 150476.44285375028 151815.76891227535 163345.97302055566 138154.48022159172 141902.9350312961 141329.07958476394 130186.774581372 131968.37508719377 141062.2826937293 1.0443596834018647 1.0667376139124358 1.076232186330727 1.1579705779695066 0.9793863928995752 1.0059594409044976 1.0018913410866455 0.922902792265386 0.9355326779570129 1.0 17.105972765385722 -6.364026600939984 8.184129602311668 0.9728356027669676 1.0840560568765236 0.6829553025668198 0.037394069899714937 0.19282554922724696 13.85044037181351 0.012445027386320215 0.014110422777878821 4.32487339972852e-07 6.364026600939984 0.11122045410955606 ISS(ph)PTETER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ISSPTETER 9 0 P31949 P31949 S100A11 Protein S100-A11;Protein S100-A11, N-terminally processed 1 IS(0.135)S(0.862)PT(0.002)ETER;IS(0.158)S(0.84)PT(0.002)ETER 133.75 0.0011541 104979000.0 102893.0 112545.0 129509.0 133137.0 147933.0 120156.0 134121.0 131212.0 121303.0 102514.0 True False 120310.75267061585 123717.72381600668 132596.98572561747 125677.76552597777 118946.59059592588 113854.80783745088 121416.08792804828 127767.82403060561 123076.82689227033 121098.97669962268 0.993491076056225 1.0216248492576416 1.0949472021924247 1.0378103015495534 0.9822262238512912 0.9401797681565844 1.0026186119574914 1.0550693945789857 1.016332509543442 1.0 16.88582714858039 -4.755375016287261 23.655626043249587 1.0176649403749942 0.9934909999967009 0.029846817455759123 0.039488264061290385 510.33879483979916 1990312.194955615 0.01100942232694575 0.09386344328702705 1.7564062899702384e-05 4.755375016287261 -0.024173940378293346 ISS(ph)PTETER ddPTM_PC-9_Lapatinib_30min_R1 3 ISSPTETER 9 0 P31949 P31949 S100A11 Protein S100-A11;Protein S100-A11, N-terminally processed 1 IS(0.005)S(0.989)PT(0.005)ET(0.001)ER;IS(0.014)S(0.984)PT(0.002)ETER;IS(0.331)S(0.668)PT(0.001)ETER 157.75 0.00010645 183852000.0 192808.0 170249.0 179400.0 165016.0 172713.0 165651.0 145816.0 156487.0 164636.0 142426.0 True False 190058.522563343 169854.79890056778 164650.4245040264 177151.82711723848 162554.3609068228 158566.49288134134 153365.63899683254 163757.95730388016 146092.95998606196 167044.144329284 1.1377742292402189 1.016825819202278 0.9856701362692546 1.0605090518350038 0.9731221741385274 0.9492490354451985 0.9181144278515513 0.9803274335739302 0.8745769603158179 1.0 17.349869884854854 -1.5228787454166093 0.3986039492214731 0.9405167358449253 3.8290454312012843 0.6076683998072607 0.04347466869364844 49.57096260253295 0.6589969897233973 0.03128157253250646 112.32063319650479 0.02999999999058668 1.5228787454166093 2.888528695356359 ISS(ph)YPEDNFPDEEKASTIK ddPTM_PC-9_AZD4547_30min_R2 1 ISSYPEDNFPDEEKASTIK 19 1 Q9Y4K4 Q9Y4K4 MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 1 IS(0.186)S(0.691)Y(0.123)PEDNFPDEEKASTIK 62.468999999999994 0.007157800000000001 5823900.0 8895.3 9495.7 9155.7 16294.0 13953.0 10502.0 8446.5 12520.0 9760.6 8611.3 True False 11723.820366265973 12564.999326465739 9034.28943577189 12537.67003979053 12015.866796311524 9845.308279812572 9198.222136961343 10585.321680978672 10276.525389340162 8309.821008075725 1.410839096879755 1.5120661822023251 1.0871821940559376 1.5087773885389417 1.445983828608842 1.1847798250100232 1.1069097791663918 1.2738326939523184 1.2366722916598487 1.0 13.020601686622495 -6.773526918034345 23.376306524711968 1.1742077298894278 1.3890317494164335 0.43658170182125056 0.13157690745817407 108.91175511759059 210623.90794591923 0.046098301807580316 0.04101216475512603 1.6845080159381557e-07 6.773526918034345 0.2148240195270057 ISSIQSIVPALEIANAHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ISSIQSIVPALEIANAHR 18 0 P10809 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 ; 145.04 0.00014539 4807100.0 28558.0 28693.0 36270.0 33949.0 46499.0 32521.0 37959.0 34883.0 33737.0 31640.0 False True 33392.305353789394 31541.45141456915 37134.81435474096 32046.947594143043 37387.85474586442 30815.541510051436 34363.24872063878 33967.35821159362 34230.339800866604 37376.081537897786 0.8934137549954505 0.8438940123401496 0.9935448775465617 0.8574186023660285 1.00031499310474 0.8244722357747899 0.919391421109671 0.9087993394158277 0.915835432512059 1.0 15.189827706198951 -9.133072757404017 1.3748291248341569 1.0000362341039288 0.9051223240808517 0.21210891463098602 0.05454374269060414 5.9089189848022 11.845331542417993 0.04914384447096438 0.014364688702631738 7.360837709665847e-10 9.133072757404017 -0.09491391002307714 ISSIQSIVPALEIANAHR ddPTM_PC-9_Lapatinib_30min_R1 2 ISSIQSIVPALEIANAHR 18 0 P10809 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 ; 124.84 3.7495e-05 4360700.0 47743.0 41904.0 43499.0 35912.0 35634.0 37617.8 41560.0 28896.4 43997.0 29357.6 False True 47062.176065006075 41806.97386257411 39922.68013099578 38553.0882789201 33538.07817913949 36008.97438537482 43711.77344535821 30239.03223549458 39041.59455105062 34432.02204345692 1.366814182612004 1.2141887516745082 1.159463713185623 1.1196870236160383 0.9740374276250993 1.045799004773162 1.2695093361112875 0.87822411931921 1.1338745805220478 1.0 15.071463286173486 -4.352054738880638 0.7306608667714924 1.0521022757746297 1.7742976888739284 0.49983948805992884 0.09835467595648177 4.161127970203401 1.088100436202777 0.03857275511068064 2.852539456295396 4.445752292620267e-05 4.352054738880638 0.7221954130992987 ISSKS(ph)PGHMVILDQTK ddPTM_PC-9_AZD4547_30min_R2 1 ISSKSPGHMVILDQTK 16 1 Q9NWH9;Q9NWH9-3 Q9NWH9 SLTM SAFB-like transcription modulator 1 IS(0.032)S(0.106)KS(0.862)PGHMVILDQTK 74.703 0.0061076 12502000.0 23315.0 22419.0 57525.0 127360.0 90048.0 66305.0 37649.0 63344.0 37780.0 66983.0 True False 30728.685017873624 29665.503322560242 56762.18091383272 97999.11969238501 77546.3895416227 62158.93786830813 40999.68806422279 53555.640300312596 39776.973670601365 64637.945558038446 0.47539699401928426 0.45894873462405406 0.878155709062039 1.5161236769877153 1.199703809769043 0.9616477957594675 0.6342975122470307 0.8285479966597168 0.6153811561799346 1.0 15.980093723983034 -5.30395277557982 4.904618422355979 0.9692711595113356 0.46331791018875373 0.38405777757840454 0.24775814381816103 0.21034394709763166 12.267354482845759 0.0739245862660992 0.16757489224620697 4.966463229642758e-06 5.30395277557982 -0.5059532493225818 ISSKS(ph)PGHMVILDQTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISSKSPGHMVILDQTK 16 1 Q9NWH9;Q9NWH9-3 Q9NWH9 SLTM SAFB-like transcription modulator 1 IS(0.035)S(0.188)KS(0.777)PGHMVILDQTK 78.985 0.004399899999999999 25653000.0 42258.0 25163.0 69311.0 134640.0 140270.0 163680.0 111600.0 153470.0 142530.0 82074.0 True False 49411.44476645535 27661.016343526404 70963.63710343138 127096.55730876983 112785.10043662005 155096.3326578281 101028.44008596864 149441.57511490618 144614.2316097319 96953.36650257354 0.5096413518053937 0.28530227821219767 0.7319357714262321 1.3109040138941042 1.1632922559076508 1.5997003327750483 1.0420312747292477 1.5413758233030452 1.4915854583130257 1.0 16.56500337331468 -5.628396882627908 2.7412213033334085 1.3316924558823555 0.40009031704858294 0.7797212554778807 0.19895271391468114 0.10948294606790474 1.6505191070815473 0.05446190449017325 0.10866369650552538 2.3528980910141873e-06 5.628396882627908 -0.9316021388337725 ISSLLEEQFQQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISSLLEEQFQQGK 13 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 0 172.11 1.5605e-18 0.0 11870.0 8149.5 13202.0 10899.0 16464.0 11107.0 10539.0 10411.0 10827.0 9525.0 False True 13879.356556813507 8958.528501830804 13516.78574886382 10288.364365034755 13237.997387812908 10524.529367243986 9540.669624247537 10137.72228136632 10985.324392328386 11251.807100141488 1.2335224407321184 0.7961857523951111 1.2012991005412677 0.9143743999046501 1.1765218928830057 0.9353634730470666 0.8479233192797596 0.9009861430382006 0.9763164525092373 1.0 13.457869104106845 -6.966111763205649 24.554027051571374 0.9185678438691012 1.0494728781897338 0.19737435318554208 0.13066702921569495 241.85656957345688 175238.487818783 0.04258417460260318 0.037555488506533924 1.0811556862506804e-07 6.966111763205649 0.1309050343206326 ISSLLEEQFQQGK ddPTM_PC-9_Lapatinib_30min_R1 2 ISSLLEEQFQQGK 13 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 0 ; 168.85 0.001068 16917700.0 56724.0 46594.0 52181.0 52655.0 55637.0 44211.0 62255.0 45090.0 52935.0 52469.0 False True 55915.105358092405 46486.114455726834 47890.87960448494 56527.42435193083 52364.54104655063 42320.19859087469 65478.25928394557 47185.04600913784 46972.90286973802 61538.19673945212 0.9086243718650476 0.7554026103908339 0.7782301422846554 0.9185745983305863 0.8509274535335829 0.6877061862903633 1.0640262918521217 0.7667602970057055 0.7633129561566061 1.0 15.909194548388825 -11.213013382606459 2.8680653548662605 1.0216389325831705 0.832421244085437 0.19200071872725444 0.10301019588503217 121059871.8237085 118510243.55322951 19138720.865385022 0.0246521325011096 6.123315226891545e-12 11.213013382606459 -0.18921768849773346 ISSLPVSRPIS(ph)PSPSAILER ddPTM_PC-9_AZD4547_30min_R2 2 ISSLPVSRPISPSPSAILER 20 1 Q5T5P2;Q5T5P2-2;Q5T5P2-7;Q5T5P2-10;Q5T5P2-3;Q5T5P1;Q5T5P2-4;Q5T5P2-8;Q5T5P2-6;Q5T5P0;Q5T5P2-9 Q5T5P2;Q5T5P2-9 KIAA1217 Sickle tail protein homolog 1 ISSLPVS(0.007)RPIS(0.985)PS(0.007)PSAILER;ISSLPVS(0.065)RPIS(0.674)PS(0.13)PS(0.13)AILER 117.29 7.9728e-05 88704000.0 55608.0 62509.0 95852.0 105713.0 107092.0 101184.0 72590.0 122952.0 97069.0 95622.0 True False 73290.18728174639 82713.81181988123 94580.93985141582 81342.50109956885 92224.124342478 94856.94848453184 79050.36937453673 103952.59355588561 102199.86916970882 92274.30288507175 0.7942643291819803 0.896390535975133 1.0249976092392374 0.8815292942487083 0.9994562024201228 1.0279887847289053 0.8566888819847762 1.1265605949400588 1.107565876677491 1.0 16.493641312772986 -2.7845620467892855 0.33594260163142564 1.0441417895678424 5.942526402766362e-16 0.4374096701397262 0.07814126583839266 26.362921494358158 0.8120783834414064 0.07363218791818542 14.677587472817137 0.0016422450186325337 2.7845620467892855 -1.0441417895678418 ISSLPVSRPIS(ph)PSPSAILER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ISSLPVSRPISPSPSAILER 20 1 Q5T5P2;Q5T5P2-2;Q5T5P2-7;Q5T5P2-10;Q5T5P2-3;Q5T5P1;Q5T5P2-4;Q5T5P2-8;Q5T5P2-6;Q5T5P0;Q5T5P2-9 Q5T5P2;Q5T5P2-9 KIAA1217 Sickle tail protein homolog 1 ISSLPVS(0.001)RPIS(0.799)PS(0.158)PS(0.042)AILER;ISSLPVS(0.028)RPIS(0.828)PS(0.135)PS(0.008)AILER 72.21 0.0016026 88696000.0 39795.0 46661.0 48541.0 52652.0 61080.0 47911.0 52406.0 56864.0 47654.0 45519.0 True False 46531.50751292276 51293.195708194035 49698.40153276764 49702.079140087175 49111.81246644872 45398.462817504835 47441.72429341647 55371.380252388255 48350.84959748929 53771.23437179423 0.865360597660576 0.9539151612837058 0.924256288950603 0.9243246825324595 0.9133473136746585 0.8442890208471513 0.8822881759675967 1.0297583996218131 0.8991954557556482 1.0 15.714546970032567 -7.742086400733664 24.999746210236324 0.9733577294390101 0.9032106167880742 0.3924984895844792 0.042773187916723916 252.6521133676044 326371.02907056117 0.020111664068272677 0.01158909009571452 1.8109797713332187e-08 7.742086400733664 -0.07014711265093587 ISSLPVSRPIS(ph)PSPSAILER ddPTM_PC-9_Lapatinib_30min_R1 1 ISSLPVSRPISPSPSAILER 20 1 Q5T5P2;Q5T5P2-2;Q5T5P2-7;Q5T5P2-10;Q5T5P2-3;Q5T5P1;Q5T5P2-4;Q5T5P2-8;Q5T5P2-6;Q5T5P0;Q5T5P2-9 Q5T5P2;Q5T5P2-9 KIAA1217 Sickle tail protein homolog 1 ISS(0.002)LPVS(0.042)RPIS(0.629)PS(0.253)PS(0.073)AILER 62.707 0.0044946000000000005 49796000.0 23188.0 27498.0 29885.0 22165.0 23369.0 26912.0 23624.0 22451.0 26634.0 18438.0 True False 22857.334867841597 27434.33007047207 27427.97065943606 23795.088040272465 21994.481365221727 25761.036494936077 24847.13512688025 23494.15542140505 23634.198451546283 21624.983732909306 1.0569873785873363 1.2686404951473786 1.2683464181152497 1.1003517197592456 1.0170866085670212 1.1912626993440207 1.1490013326145265 1.0864357500371757 1.0929117331810667 1.0 14.400411427052111 -8.934187597727108 0.18359364621870386 0.9281038115079085 1.2211921789845541 0.2723909352299546 0.07683253177511237 9.526759524778006 0.9480695937568849 0.8516990451634069 0.4135829585947669 1.1636232824362761e-09 8.934187597727108 0.2930883674766456 ISSPTETER ddPTM_PC-9_AZD4547_30min_R2 1 ISSPTETER 9 0 P31949 P31949 S100A11 Protein S100-A11;Protein S100-A11, N-terminally processed 0 102.51 0.014525999999999999 5391600.0 17332.0 19423.0 30437.0 33591.0 32431.0 30927.0 18063.0 31501.0 19453.0 26625.0 False True 22843.215472004533 25701.104912533454 30033.385492817484 25847.11392577658 27928.515449808558 28993.129800967745 19670.572007332357 26633.244270967196 20481.2458659134 25692.866854019263 0.8890878391187029 1.0003206360178098 1.1689386654848606 1.0060034978826502 1.0870143689488494 1.1284505526650563 0.7656044037084633 1.0366007196585314 0.7971568911434815 1.0 14.64908025714969 -7.246688305623683 24.964100266196546 0.902890551850956 1.0500783546711416 0.3207214289659588 0.10454969261739104 944.6890250791367 1598754.7267571 0.038935269059974624 0.0300205796729209 5.6664582644439856e-08 7.246688305623683 0.14718780282018562 ISSPTETER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ISSPTETER 9 0 P31949 P31949 S100A11 Protein S100-A11;Protein S100-A11, N-terminally processed 0 ;;; 107.01 0.0074203 17433200.0 76039.0 68443.0 88977.0 88876.0 106834.0 90782.0 99448.0 72896.0 89357.0 61495.0 False True 88910.90086129257 75237.56871597096 91098.54912715178 83896.56585987954 85900.64461428572 86021.23210742255 90027.56549883 70982.55723969651 90663.6770781646 72643.55670584795 1.2239337512246984 1.0357087693355491 1.2540485799178687 1.154907188804065 1.1824950279089315 1.184155016744901 1.2393055844357164 0.9771349374745342 1.2480621983486389 1.0 16.148547219792142 -10.88864828029489 4.813014515824074 0.9998559707293928 1.1625590666825791 0.24456607206358016 0.08759764889567347 0.0001268129293034987 1.6710642383908776e-05 0.0794474097931783 0.01925181924246793 1.2922654098865439e-11 10.88864828029489 0.16270309595318633 ISSPTETER ddPTM_PC-9_Lapatinib_30min_R1 3 ISSPTETER 9 0 P31949 P31949 S100A11 Protein S100-A11;Protein S100-A11, N-terminally processed 0 ;; 107.01 0.011663 75333000.0 77873.0 64262.0 68814.0 66124.0 66334.0 58586.0 67141.0 75335.0 71345.0 64020.0 False True 76762.5167398407 64113.2052872455 63156.378549721616 70986.97954319755 62432.36453766177 56080.41335063638 70617.23245656399 78835.33912393883 63309.37480384353 75085.77169871201 1.0223310622398178 0.8538662363956936 0.8411231198787157 0.9454118661527352 0.8314806270910673 0.74688469042662 0.9404875365724626 1.049937123111317 0.8431607396655353 1.0 16.196251931170934 -10.569646297587546 4.794085009054902 1.0000018675300173 0.8950953001256403 0.10820789578201429 0.08836310497870395 2.7482076000842474e-06 5.464758716005345e-07 0.08814767857446078 0.02137837684187763 2.6937277632388436e-11 10.569646297587546 -0.10490656740437698 ISST(ph)PTTETIR ddPTM_PC-9_AZD4547_30min_R2 1 ISSTPTTETIR 11 0 A0A075B754;Q96QE3;Q96QE3-2 A0A075B754 ATAD5 ATPase family AAA domain-containing protein 5 1 IS(0.263)S(0.023)T(0.714)PTTETIR 132.17 0.00029775 4503000.0 15312.0 24379.0 32724.0 37786.0 41776.0 31837.0 22163.0 33483.0 21657.0 29528.0 True False 20180.897490614654 32259.034992671215 32290.058378518246 29075.02148788048 35976.12350625028 29846.227357112235 24135.464064579915 28308.971712796254 22801.744806358216 28494.233707623724 0.7082449627418894 1.1321250230372122 1.1332137831760303 1.02038264254502 1.2625755749530738 1.047447973627267 0.8470297644158928 0.9934982636582397 0.8002231272588157 1.0 14.798382374507375 -7.174981917364981 6.712647645281023 0.9100750879274314 1.0673975891220129 0.17994570291027678 0.14460322333923253 0.40268484455109227 26.40588040216867 0.054855452072145414 0.042357210416881896 6.683717458538789e-08 7.174981917364981 0.15732250119458147 ISST(ph)PTTETIR ddPTM_PC-9_Lapatinib_30min_R1 2 ISSTPTTETIR 11 0 A0A075B754;Q96QE3;Q96QE3-2 A0A075B754 ATAD5 ATPase family AAA domain-containing protein 5 1 ISS(0.003)T(0.996)PTTETIR;ISS(0.034)T(0.937)PT(0.025)T(0.003)ETIR 164.48 0.00041556 15571900.0 62100.0 61704.0 76225.0 49063.0 53197.0 63553.0 49525.0 50356.0 62316.0 41728.0 True False 61214.44261225472 61561.128179082465 69958.0747370089 52671.25668937004 50068.05704932606 60834.98633927885 52089.16217231392 52695.723593615985 55297.315863428594 48940.62920093501 1.2507898572559673 1.257873655982877 1.4294477999002178 1.0762276159776827 1.0230366439254834 1.243036457286017 1.0643337248169003 1.0767275462941788 1.1298856750777562 1.0 15.57874502896907 -5.780100893014383 24.999435191201137 1.0936198430037256 1.3072207629620076 0.6410344322326721 0.07706606894696195 148.1966325865456 198527.48320981298 0.021497809212503275 0.03194755426032362 1.6592014056991559e-06 5.780100893014383 0.213600919958282 ISSVPNS(ph)LSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISSVPNSLSK 10 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;X6R5W5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 IS(0.017)S(0.151)VPNS(0.814)LS(0.018)K 92.866 0.0071589 3016400.0 31582.0 32532.0 33622.0 42912.0 39592.0 39794.0 35631.0 34640.0 35026.0 33338.0 True False 36928.2088270669 35761.56196350203 34423.67599214507 40507.7797625811 31834.231813550075 37707.132586666696 32255.773733899234 33730.73670411386 35538.18898731815 39381.9154965372 0.9376945829441421 0.9080706591492863 0.8740985693083391 1.028588357164671 0.8083464557824572 0.9574732998952841 0.8190504023791184 0.856503201503232 0.9023986908519718 1.0 15.265245663723086 -6.280092404780633 24.952009105189262 0.8832171642874619 0.9305375742856344 0.0975795411031739 0.06581191153121728 1838.8658275973005 2459830.3318672157 0.01939480032991735 0.02203410485186433 5.246958089129084e-07 6.280092404780633 0.04732040999817255 IST(ph)PLT(ph)RKEST(ph)DMAIT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 ISTPLTRKESTDMAITPK 18 2 Q8WXI7 Q8WXI7 MUC16 Mucin-16 4 IS(0.221)T(0.871)PLT(0.871)RKES(0.188)T(0.854)DMAIT(0.995)PK 43.791000000000004 0.028385000000000004 6019200.0 3825.5 4502.5 3709.4 2845.0 3745.8 4923.3 3093.9 3242.2 5372.0 1531.6 True False 3770.94766848922 4492.074737882776 3404.4274506980782 3054.2307906417823 3525.4794085261487 4712.741935772844 3254.087003431035 3392.8444482330146 4766.948790332157 1796.3350192712815 2.0992452009419598 2.500688729936955 1.8952074163087635 1.7002567772022787 1.9625957133298713 2.623531738352827 1.8115145385024667 1.8887592858983446 2.6537080996539073 1.0 10.81084072470079 -10.681053755294519 4.573495116389664 0.999844571206358 2.1114434323590103 0.5121343798649554 0.32946620390629416 18378554.081571948 42921802.71725796 17320.204733968007 0.08027245197221025 2.0842328888293678e-11 10.681053755294519 1.1115988611526524 IST(ph)PLTGVR ddPTM_PC-9_AZD4547_30min_R2 2 ISTPLTGVR 9 0 Q08999;F5H837;Q08999-2 Q08999 RBL2 Retinoblastoma-like protein 2 1 IS(0.004)T(0.996)PLTGVR;IS(0.044)T(0.956)PLTGVR 125.68 0.0034689 30078000.0 105605.0 125938.0 162600.0 199558.0 205284.0 187788.0 165618.0 184387.0 166236.0 191673.0 True False 139185.19327954305 166644.99564818197 160443.81775904752 153552.9862403656 176783.86005977303 176045.58667391387 180357.68115542128 155894.22594174262 175022.89558247963 184962.586610721 0.7525045785203971 0.9009659666952491 0.8674393059647433 0.8301840337232027 0.955781724829783 0.9517902506652648 0.9751035842454379 0.8428419433268595 0.9462610725207861 1.0 17.496873952909056 -2.681874713084867 0.386125477021475 0.9454631671883122 8.903342263986957e-14 0.5195345183959743 0.051162013974615984 26.428110002106305 0.8350396730306114 0.040334236629861235 16.19067505554947 0.0020802967324192703 2.681874713084867 -0.9454631671882232 IST(ph)PLTGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ISTPLTGVR 9 0 Q08999;F5H837;Q08999-2 Q08999 RBL2 Retinoblastoma-like protein 2 1 IS(0.019)T(0.981)PLTGVR;IS(0.031)T(0.969)PLTGVR;IS(0.042)T(0.958)PLTGVR 136.52 0.0024385 22088700.0 127395.0 159301.0 168852.0 205222.0 208430.0 184209.0 207810.0 196682.0 170484.0 165651.0 True False 148960.45733405673 175115.35049636735 172878.07205477572 193724.07667870063 167589.6377272742 174548.75575858876 188124.7323858888 191519.30590180465 172977.00597595942 195682.21500740576 0.7612365657677127 0.8948966082060138 0.8834633850001801 0.989993273897523 0.8564377591542064 0.8920011241286431 0.9613787966309001 0.9787261754705529 0.8839689696348386 1.0 17.578153113965207 -3.915089983336977 1.0798605387971136 0.9321745364978302 7.937593730731483e-13 0.5385817551755456 0.047449823595467976 7.496818214475032 1.7918097511501792 0.014503081739624064 12.506772019355793 0.00012159340399543505 3.915089983336977 -0.9321745364970364 IST(ph)PLTGVR ddPTM_PC-9_Lapatinib_30min_R1 1 ISTPLTGVR 9 0 Q08999;F5H837;Q08999-2 Q08999 RBL2 Retinoblastoma-like protein 2 1 IS(0.029)T(0.971)PLTGVR 128.03 0.0032840000000000005 13815000.0 115270.0 107750.0 101300.0 96416.0 105540.0 94521.0 90238.0 79874.0 107690.0 77592.0 True False 113626.2286620712 107500.51149514006 92971.50502930807 103506.75427434717 99332.34469962353 90478.5571692127 94910.08210207503 83585.23763437298 95560.81817402641 91003.6738151591 1.2485894678588647 1.1812766121232456 1.0216236458557257 1.137390941871023 1.0915201610583447 0.9942297203625758 1.0429258306082279 0.9184820142991812 1.0500764877704114 1.0 16.473637167585238 -1.5228787452807726 0.33586311349015263 0.9864914822736094 3.8369202736553407 0.6918990249419454 0.051573930549262584 33.019510665931755 0.46889090707775627 0.04598378792610294 58.77461271197658 0.02999999999996995 1.5228787452807726 2.850428791381731 IST(ph)YGLPAGGIQPHPQTK ddPTM_PC-9_Lapatinib_30min_R1 1 ISTYGLPAGGIQPHPQTK 18 0 Q9Y5K6 Q9Y5K6 CD2AP CD2-associated protein 1 IS(0.467)T(0.531)Y(0.002)GLPAGGIQPHPQTK 77.28699999999999 0.010487 5778800.0 20601.0 25682.0 28088.0 30964.0 23411.0 24678.0 23541.0 21436.0 29085.0 25000.0 True False 20307.22596223929 25622.534906897363 25778.713062815455 33241.19585287599 22034.01100779689 23622.579467227737 24759.837793002367 22431.994815965376 25809.141021372052 29321.21668959394 0.6925778755097258 0.8738564698098209 0.8791829253103363 1.1336908766365499 0.751469873882032 0.8056479960332396 0.8444341875413921 0.7650431103674651 0.880220670738117 1.0 14.839657349174805 ISTLSCENK ddPTM_PC-9_Lapatinib_30min_R1 1 ISTLSCENK 9 0 Q14116-2;Q14116 Q14116-2 IL18 Interleukin-18 0 113.62 0.0017139 0.0 22417.0 12718.0 11362.0 7579.1 12443.0 10448.0 7563.9 9132.8 12187.0 10267.0 False True 22097.32946922567 12688.552252391599 10427.860218588332 8136.492297136431 11711.127203879238 10001.163395477572 7955.521731553057 9557.14322892557 10814.371725200659 12041.637270082438 1.8350768233259025 1.0537231746646636 0.8659835855126155 0.6756965115824926 0.9725527302649819 0.8305484687140973 0.6606677774058705 0.7936747316471975 0.8980815052508738 1.0 13.555743944474159 -4.695857768200148 2.127266430480463 0.8217193005676632 2.272968394868228 0.889661652211584 0.10524168843545674 0.26705022297680664 1.1275514361637056 0.027766953135675544 0.8110539831045916 2.014383854214266e-05 4.695857768200148 1.451249094300565 ISTPQTNTVPIKPLIS(ph)TPPVSSQPK ddPTM_PC-9_AZD4547_30min_R2 1 ISTPQTNTVPIKPLISTPPVSSQPK 25 1 Q9BTA9-2;Q9BTA9;A0A0A0MRT2;Q9BTA9-5 Q9BTA9-2 WAC WW domain-containing adapter protein with coiled-coil 1 ISTPQTNTVPIKPLIS(0.495)T(0.495)PPVS(0.009)S(0.002)QPK 85.376 4.8235000000000005e-06 5252200.0 15390.0 12659.0 15817.0 26151.0 22771.0 22866.0 11750.0 17895.0 15012.0 16876.0 True False 20283.699868113876 16750.774189762706 15607.256245355786 20122.290978922425 19609.639706071055 21436.185405274628 12795.727237233865 15129.738936191176 15805.503672394594 16285.176376654623 1.245531482065572 1.0285902837242544 0.9583719503173045 1.235620082553631 1.2041404558677158 1.3163004753208665 0.7857285018771423 0.9290497435373308 0.9705454400268175 1.0 13.991271724481116 -7.26618463317133 24.99978826066385 0.9154184032103474 1.154199407263552 0.5306641280006716 0.11183297597663144 360.422972587002 1898833.9423645576 0.04879021570547597 0.03412407061457295 5.417705165916934e-08 7.26618463317133 0.23878100405320457 ISVGRLS(ph)PQQESSASSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ISVGRLSPQQESSASSK 17 1 F5H212;P15822 F5H212 HIVEP1 Zinc finger protein 40 1 IS(0.011)VGRLS(0.988)PQQESSASSK;IS(0.059)VGRLS(0.939)PQQES(0.002)SASSK 66.436 0.0095 18978200.0 80777.0 77508.0 72262.0 91868.0 97367.0 90081.0 76791.0 84958.0 71965.0 59758.0 True False 94450.95068152681 85202.48200747297 73985.0001351611 86720.93380007449 78288.63530485774 85356.99378146268 69516.80056130505 82727.94252044162 73017.35198059597 70591.65235593225 1.3379903647146958 1.2069767339893251 1.0480700998769537 1.2284870931029679 1.1090353135540205 1.2091655448307352 0.9847736699913516 1.1719224548437628 1.0343624145873938 1.0 16.10720997074087 -1.5228787452803376 0.25842394295525856 1.0463942109635644 2.64148301261069 0.48272622196324366 0.07914800929276258 48.55574291337697 0.6685850822564423 0.09593207151232049 34.03844828453786 0.029999999999999995 1.5228787452803376 1.5950888016471254 ISVGRLS(ph)PQQESSASSK ddPTM_PC-9_Lapatinib_30min_R1 1 ISVGRLSPQQESSASSK 17 1 F5H212;P15822 F5H212 HIVEP1 Zinc finger protein 40 1 IS(0.008)VGRLS(0.988)PQQES(0.003)S(0.001)ASSK 81.37899999999999 0.002424 5557200.0 16656.0 21094.0 22662.0 17543.0 20066.0 16160.0 20117.0 16916.0 17526.0 16814.0 True False 16418.482385663683 21045.158139011502 20798.817837849747 18833.17074173244 18885.757331273882 15468.874470799912 21158.559826763038 17701.979114894108 15552.037323038232 19720.277496753297 0.8325685269067226 1.0671836713492664 1.0546919454492474 0.955015503449842 0.9576821286811604 0.7844146449433419 1.072934183114134 0.8976536520750543 0.7886317687770208 1.0 14.267392232501232 -6.304531019876875 2.997311043793555 0.9104842875026289 0.9916250292205143 0.08291229063739458 0.10115844563276757 0.6068824053757937 10.923573647664622 0.032663156846704074 0.03954189808694848 4.959854999170361e-07 6.304531019876875 0.08114074171788543 ISVSS(ph)PGR ddPTM_PC-9_AZD4547_30min_R2 3 ISVSSPGR 8 0 O75864-2;O75864 O75864-2 PPP1R37 Protein phosphatase 1 regulatory subunit 37 1 IS(0.002)VS(0.151)S(0.848)PGR;ISVS(0.075)S(0.924)PGR;IS(0.004)VS(0.053)S(0.942)PGR 114.89 0.0036576 86241000.0 222759.0 260439.0 347568.0 535250.0 448109.0 402353.0 336132.0 454378.0 376860.0 467785.0 True False 293591.72832496255 344620.81358777237 342959.02122310275 411856.382030065 385896.8002743751 377193.8033048396 366047.0968260328 384164.32066771097 396780.0502250613 451407.98953267257 0.6503910766597377 0.7634353435891701 0.7597539901279918 0.9123816848178651 0.8548736602422147 0.8355939904726445 0.8109007933266511 0.8510357139788849 0.8789832245455697 1.0 18.78407242765234 -3.71953523961094 0.5966829085990634 0.8732581415353167 5.169145889477993e-20 0.6448603986638156 0.053679897350256536 7.641589331017156 0.7890076385179846 0.024887734656893354 6.106602509030299 0.00019075009388822632 3.71953523961094 -0.8732581415353167 ISVSS(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ISVSSPGR 8 0 O75864-2;O75864 O75864-2 PPP1R37 Protein phosphatase 1 regulatory subunit 37 1 IS(0.026)VS(0.156)S(0.818)PGR;IS(0.002)VS(0.152)S(0.847)PGR;ISVS(0.025)S(0.974)PGR;IS(0.001)VS(0.022)S(0.977)PGR 109.44 0.003778 92455000.0 243559.0 320671.0 459174.0 506193.0 603145.0 503014.0 533806.0 487800.0 451549.0 392468.0 True False 284788.7281904757 352505.09763919085 470122.44958709256 477832.6473098477 484963.0669626113 476635.0603344611 483240.0312592345 474995.7668668229 458152.04987822066 463619.34162502177 0.6142727505549469 0.7603330275299411 1.014026826273634 1.030657275071845 1.0460371762376826 1.0280741495033796 1.0423206882729281 1.0245382886786516 0.9882073691584181 1.0 18.82258122948791 -5.104338541290394 2.389074671536562 1.0275775776880975 0.6123780014798588 0.9806839476044393 0.019278692197690954 0.04146172896739022 0.419737244746556 0.005526669070636611 0.02635561876730437 7.86432510722589e-06 5.104338541290394 -0.4151995762082388 ISVSS(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 1 ISVSSPGR 8 0 O75864-2;O75864 O75864-2 PPP1R37 Protein phosphatase 1 regulatory subunit 37 1 IS(0.004)VS(0.157)S(0.839)PGR 70.816 0.037106 38487000.0 345400.0 282830.0 239080.0 275940.0 268440.0 207710.0 427320.0 322590.0 253380.0 190130.0 True False 340474.5326613977 282175.1245120233 219423.7652754885 296233.5481088553 252650.88697334594 198826.72749565885 449444.5387071814 337578.70907269337 224841.67619031318 222993.71716769997 1.5268346435309994 1.2653949541538725 0.9839907960746412 1.3284389886468242 1.1329955398848417 0.8916247956265665 2.01550314697513 1.5138485216550788 1.008287045240936 1.0 17.76664353732368 ISVYYNEATGGK ddPTM_PC-9_Lapatinib_30min_R1 2 ISVYYNEATGGK 12 0 Q5JP53;P07437 Q5JP53 TUBB Tubulin beta chain 0 ; 193.22 8.488799999999999e-05 52205000.0 198942.0 172037.0 196203.0 178650.0 196774.0 185659.0 198766.0 165398.0 182498.0 188478.0 False True 196105.05059850565 171638.65889642137 180071.94670548214 191788.51695892957 185200.14019256868 177718.79736226727 209057.1309104927 173082.99489508523 161943.15345086335 221056.1711688518 0.887127690494162 0.7764481669471995 0.814598143781002 0.8676008271781456 0.8377967428518663 0.803953114824007 0.9457194965654511 0.7829819632715763 0.7325882493783198 1.0 17.75405348464114 -5.732589637651494 24.228623573336293 0.8450988751555891 0.8210970040722345 0.016805825339128888 0.07699640283706388 856.4304545724276 719238.8259694348 0.020352205522603313 0.03524161018745053 1.8510168080160002e-06 5.732589637651494 -0.02400187108335461 ISY(ph)IPDEEVS(ph)S(ph)PS(ph)PPQR ddPTM_PC-9_Lapatinib_30min_R1 1 ISYIPDEEVSSPSPPQR 17 0 F8W930;Q9Y6M1-5;Q9Y6M1-6;Q9Y6M1-3;Q9Y6M1-4;Q9Y6M1-1;Q9Y6M1 F8W930 IGF2BP2 Insulin-like growth factor 2 mRNA-binding protein 2 4 IS(0.24)Y(0.765)IPDEEVS(0.998)S(0.998)PS(0.999)PPQR 45.722 0.033895 1849500.0 4976.4 7460.0 3109.9 2444.4 4125.6 4095.5 3032.9 3367.2 5178.9 808.66 True False 4905.43562344001 7442.726828341037 2854.216026561158 2624.169330279358 3882.9403192416753 3920.3450120767943 3189.9287219063285 3523.6524045679507 4595.597745765298 948.4358035282806 5.172132478752147 7.847370165332554 3.0093929562160926 2.7668391687841947 4.094046539361684 4.133484836288023 3.363357551496326 3.7152249962091206 4.845449453372798 1.0 9.889406315477101 -5.271545108137639 24.97317208659045 3.4948691963949385 6.509751360936172 0.5424676901491737 1.1500130815018486 432.5700600311515 1068963.8028624011 0.2831911934467995 0.600387917963613 5.351245699971844e-06 5.271545108137639 3.0148821645412336 ISY(ph)TPPES(ph)PVPSYASSTPLHVPVPR ddPTM_PC-9_Lapatinib_30min_R1 1 ISYTPPESPVPSYASSTPLHVPVPR 25 0 P41212 P41212 ETV6 Transcription factor ETV6 2 IS(0.122)Y(0.463)T(0.465)PPES(0.95)PVPSYASSTPLHVPVPR 89.721 6.6611e-05 4620800.0 15124.0 11192.0 22886.0 14455.0 16986.0 20458.0 13337.0 15305.0 20093.0 12299.0 True False 14908.328986598084 11166.085611634437 21004.40142251477 15518.068920466427 15986.916875760891 19583.05902992727 14027.524601557807 16016.126173649463 17829.91475132985 14424.865762612622 1.0335159600055714 0.7740859287977209 1.4561245676861305 1.075786019491928 1.1082887798648984 1.3575903826213769 0.9724544292062203 1.1103137067078421 1.2360541196537629 1.0 13.816270272803973 -5.2357663309410745 24.97934192991772 1.1633668068681955 0.9038009561793103 0.31279419864078195 0.15460280765562245 872.0154022069743 848450.0909671085 0.037425314737916895 0.09894460561918313 5.810769777658244e-06 5.2357663309410745 -0.25956585068888516 ISYIPDEEVS(ph)SPSPPQR ddPTM_PC-9_AZD4547_30min_R2 4 ISYIPDEEVSSPSPPQR 17 0 F8W930;Q9Y6M1-5;Q9Y6M1-6;Q9Y6M1-3;Q9Y6M1-4;Q9Y6M1-1;Q9Y6M1 F8W930 IGF2BP2 Insulin-like growth factor 2 mRNA-binding protein 2 1 ISYIPDEEVS(0.619)S(0.359)PS(0.022)PPQR;ISYIPDEEVS(0.483)S(0.483)PS(0.034)PPQR;ISYIPDEEVS(0.675)S(0.272)PS(0.053)PPQR;ISYIPDEEVS(0.529)S(0.46)PS(0.011)PPQR 231.06 1.3516e-29 189899500.0 330517.0 280081.0 432258.0 519563.0 462172.0 430971.0 375461.0 510687.0 368234.0 384135.0 True False 435614.5308193247 370611.7059675271 426525.97648764006 399785.7775183309 398007.39546942426 404022.31524082174 408876.30163566535 431772.0585698039 387698.0974753898 370686.55057159375 1.175156018333044 0.999798091935218 1.150637852465763 1.078500897596275 1.0737033616561003 1.0899297927530003 1.1030243773484187 1.1647901924254256 1.0458919992580373 1.0 18.499840245985403 ISYIPDEEVS(ph)SPSPPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ISYIPDEEVSSPSPPQR 17 0 F8W930;Q9Y6M1-5;Q9Y6M1-6;Q9Y6M1-3;Q9Y6M1-4;Q9Y6M1-1;Q9Y6M1 F8W930 IGF2BP2 Insulin-like growth factor 2 mRNA-binding protein 2 1 ISY(0.001)IPDEEVS(0.643)S(0.354)PS(0.002)PPQR;ISYIPDEEVS(0.624)S(0.368)PS(0.008)PPQR 229.92 2.2630999999999999e-29 48103000.0 65603.0 78967.0 93574.0 83150.0 99254.0 87027.0 98336.0 92675.0 79506.0 72975.0 True False 76708.29218168798 86806.32188527807 95805.15904137096 78491.37507593734 79805.89120080063 82463.1509177224 89020.90218901273 90242.37944727927 80668.6248394254 86204.7898302177 0.8898379351398769 1.0069779423654428 1.1113670044328325 0.9105222021946563 0.9257709618917945 0.9565959279076657 1.032667701694319 1.046837184163591 0.9357789166739354 1.0 16.395480412115788 -7.250827538777657 24.488754253069363 1.0077240501123044 0.9708115472086766 0.07104452897586822 0.06393269990200703 1740.0858968006723 4015572.084133268 0.02594915794236184 0.019886745181099792 5.6127081615165235e-08 7.250827538777657 -0.0369125029036278 ISYIPDEEVS(ph)SPSPPQR ddPTM_PC-9_Lapatinib_30min_R1 2 ISYIPDEEVSSPSPPQR 17 0 F8W930;Q9Y6M1-5;Q9Y6M1-6;Q9Y6M1-3;Q9Y6M1-4;Q9Y6M1-1;Q9Y6M1 F8W930 IGF2BP2 Insulin-like growth factor 2 mRNA-binding protein 2 1 ISYIPDEEVS(0.897)S(0.094)PS(0.009)PPQR;ISYIPDEEVS(0.779)S(0.21)PS(0.011)PPQR 249.54 1.2475e-47 114313000.0 273096.0 328293.0 370994.0 320723.0 377812.0 361438.0 321340.0 289588.0 360014.0 278284.0 True False 269201.60096032766 327532.85772876185 340492.3053982532 344310.03932056326 355589.8409669716 345980.13929313014 337977.4128713043 303043.315672969 319465.43220451253 326385.01860987884 0.8247976641418664 1.003516825385466 1.0432228380103332 1.0549198636231212 1.0894796657073302 1.0600368263430404 1.035517544006153 0.9284841472310048 0.9787993136607868 1.0 18.316215312159002 -4.762760723209336 4.023412511816219 1.0263521392776922 0.8030064515602604 0.6509724523245759 0.0434112394319594 0.17110154334548755 5.220878602616521 0.012449270556651144 0.11478785857269475 1.7267890132901303e-05 4.762760723209336 -0.2233456877174318 ISYIPDEEVSS(ph)PSPPQR ddPTM_PC-9_AZD4547_30min_R2 2 ISYIPDEEVSSPSPPQR 17 0 F8W930;Q9Y6M1-5;Q9Y6M1-6;Q9Y6M1-3;Q9Y6M1-4;Q9Y6M1-1;Q9Y6M1 F8W930 IGF2BP2 Insulin-like growth factor 2 mRNA-binding protein 2 1 ISYIPDEEVS(0.045)S(0.499)PS(0.456)PPQR;ISYIPDEEVS(0.203)S(0.66)PS(0.137)PPQR 168.55 1.8553e-05 90989000.0 95708.0 104680.0 133729.0 175077.0 163210.0 153414.0 122498.0 164730.0 142230.0 151483.0 True False 126141.15314993155 138515.76287102918 131955.66608302362 134715.70256268585 140551.1087096684 143820.9983278584 133400.08468992973 139274.76361881915 149747.9874317002 146179.62627783662 0.8629188373363406 0.9475722875892355 0.9026953306900771 0.921576460365538 0.9614958820768198 0.983864865371216 0.9125764519084388 0.9527645347382834 1.0244107968033886 1.0 17.157382724741133 -1.5228787453757249 0.14792642014077356 1.018112924291557 0.5415792267655165 0.5653414389000192 0.030404483902243134 57.01104574719014 0.5567344072715606 0.11445883696407154 5.8092046955561925 0.029999999993410877 1.5228787453757249 -0.47653369752604047 ISYIPDEEVSS(ph)PSPPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 ISYIPDEEVSSPSPPQR 17 0 F8W930;Q9Y6M1-5;Q9Y6M1-6;Q9Y6M1-3;Q9Y6M1-4;Q9Y6M1-1;Q9Y6M1 F8W930 IGF2BP2 Insulin-like growth factor 2 mRNA-binding protein 2 1 ISYIPDEEVS(0.327)S(0.672)PS(0.001)PPQR;ISYIPDEEVS(0.409)S(0.547)PS(0.044)PPQR;ISYIPDEEVS(0.046)S(0.538)PS(0.417)PPQR;ISYIPDEEVS(0.03)S(0.941)PS(0.03)PPQR;ISYIPDEEVS(0.021)S(0.817)PS(0.162)PPQR 226.7 4.8301e-29 236485000.0 520249.0 598542.0 683367.0 609894.0 797335.0 569784.0 635049.0 585079.0 592012.0 448100.0 True False 608316.8803138712 657961.2941337266 699661.0609637802 575723.6164830253 641102.9304671875 539903.5239925947 574892.5613633894 569721.2961924422 600669.0555233314 529336.982842351 1.1492053267229247 1.2429913560936343 1.3217687099942452 1.0876315752426642 1.2111432815910448 1.0199618418752932 1.0860615826924112 1.0762922574070715 1.1347573946145848 1.0 19.013826927766026 -6.334081840398006 1.4188884059263271 1.0722748222903413 1.2284344208553954 0.4729989322057484 0.06964857093056061 0.3607546398190136 1.4650345991316684 0.02650774578390528 0.0346128895528095 4.6335959395057054e-07 6.334081840398006 0.15615959856505413 ISYIPDEEVSS(ph)PSPPQR ddPTM_PC-9_Lapatinib_30min_R1 2 ISYIPDEEVSSPSPPQR 17 0 F8W930;Q9Y6M1-5;Q9Y6M1-6;Q9Y6M1-3;Q9Y6M1-4;Q9Y6M1-1;Q9Y6M1 F8W930 IGF2BP2 Insulin-like growth factor 2 mRNA-binding protein 2 1 ISYIPDEEVS(0.359)S(0.627)PS(0.014)PPQR;ISYIPDEEVS(0.062)S(0.934)PS(0.004)PPQR 199.33 1.943e-12 110615000.0 231617.0 309577.0 322893.0 313498.0 335895.0 331310.0 267268.0 281013.0 349930.0 277966.0 True False 228314.09910664428 308860.1934768547 296345.98394302477 336553.68871867034 316138.3164949786 317140.6436213313 281105.8292876325 294069.889868393 310517.1984737396 326012.0527335872 0.7003241051741715 0.9473888799112934 0.9090031532827862 1.0323351112227057 0.9697135852622072 0.9727880946797218 0.8622559409401606 0.902021527739967 0.9524715294114914 1.0 18.314565776615694 -4.761331505970129 24.914501114087194 0.9466266057602999 0.7003238450719139 0.717910532219159 0.04687258272098131 1.399920873046157 321803.8707077318 0.012312389641598363 0.0690011740556719 1.7324810542434622e-05 4.761331505970129 -0.24630276068838597 ISYIPDEEVSSPS(ph)PPQR ddPTM_PC-9_AZD4547_30min_R2 3 ISYIPDEEVSSPSPPQR 17 0 F8W930;Q9Y6M1-5;Q9Y6M1-6;Q9Y6M1-3;Q9Y6M1-4;Q9Y6M1-1;Q9Y6M1 F8W930 IGF2BP2 Insulin-like growth factor 2 mRNA-binding protein 2 1 ISYIPDEEVSS(0.001)PS(0.999)PPQR;ISYIPDEEVSSPS(1)PPQR;ISYIPDEEVSSPS(1)PPQR 197.1 3.125e-12 117604000.0 293279.0 295716.0 394782.0 549386.0 445385.0 398960.0 366526.0 511001.0 393914.0 437174.0 True False 386535.62141784094 391300.4139584386 389546.9327340234 422733.54562908784 383550.98065471265 374012.9681312159 399146.1039450543 432037.5370848079 414735.4898486305 421868.67132541025 0.9162463289901065 0.927540821481402 0.9233843591896983 1.0020501031777505 0.9091715188276186 0.8865625573858253 0.9461382915470659 1.0241043396928469 0.9830914643309042 1.0 18.686434429020252 -7.637425548830405 5.4834502601779915 1.0020705944271635 0.9288751404999831 0.5650553043789321 0.029361282477727124 0.1627847853337883 7.15049846491802 0.01492082047583602 0.00841448509854611 2.3044880009264903e-08 7.637425548830405 -0.07319545392718041 ISYIPDEEVSSPS(ph)PPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ISYIPDEEVSSPSPPQR 17 0 F8W930;Q9Y6M1-5;Q9Y6M1-6;Q9Y6M1-3;Q9Y6M1-4;Q9Y6M1-1;Q9Y6M1 F8W930 IGF2BP2 Insulin-like growth factor 2 mRNA-binding protein 2 1 ISYIPDEEVS(0.007)S(0.455)PS(0.538)PPQR;ISYIPDEEVSS(0.001)PS(0.998)PPQR;ISYIPDEEVS(0.055)S(0.055)PS(0.889)PPQR 161.99 2.9156e-05 60521000.0 181831.0 229532.0 254217.0 265477.0 271678.0 201044.0 264122.0 202333.0 192371.0 190708.0 True False 212611.3969740481 252318.4200358589 260278.49740334152 250603.18437804622 218444.64615684096 190500.89872226512 239102.45208231363 197021.973139534 195184.06194482328 225281.8507563032 0.9437573255913932 1.120012194452372 1.1553460544182748 1.1123984623560916 0.96965044198408 0.8456113889455654 1.0613480459238624 0.8745576817577769 0.8663994071851 1.0 17.78137156573512 -6.3741565289077595 4.474609288341947 0.9281490262684263 1.090238235665727 0.4504790327182372 0.0799013837142761 0.20549070371484385 6.6844087800029 0.02544384179325148 0.029002240055563372 4.225163030159355e-07 6.3741565289077595 0.16208920939730065 ISYIPDEEVSSPS(ph)PPQR ddPTM_PC-9_Lapatinib_30min_R1 2 ISYIPDEEVSSPSPPQR 17 0 F8W930;Q9Y6M1-5;Q9Y6M1-6;Q9Y6M1-3;Q9Y6M1-4;Q9Y6M1-1;Q9Y6M1 F8W930 IGF2BP2 Insulin-like growth factor 2 mRNA-binding protein 2 1 ISYIPDEEVS(0.003)S(0.049)PS(0.948)PPQR;ISYIPDEEVSSPS(0.999)PPQR 218.83 1.401e-22 60410000.0 184145.0 246538.0 267423.0 231231.0 242358.0 231932.0 202826.0 207029.0 288773.0 202431.0 True False 181519.05853194295 245967.1564082501 245436.51322263185 248236.4991040036 228102.97893416087 222012.80901989894 213327.33784475984 216648.32313652197 256248.3438255002 237420.92862764737 0.7645453144386585 1.0359961012283208 1.0337610700173594 1.045554410636303 0.9607534611740145 0.9351021003210996 0.8985195158566915 0.9125072687938831 1.0792997285735508 1.0 17.857087588424626 -1.5229846226402526 0.0059827859471052215 1.866732823044696 4.1303470306002775e-05 0.048141516578468324 0.08660098072362012 209115.52325335538 97.1587514910541 13870.968968182508 16553.242849003833 0.029992687142524167 1.5229846226402526 -1.86669151957439 ISYT(ph)PPES(ph)PVPSYASSTPLHVPVPR ddPTM_PC-9_AZD4547_30min_R2 7 ISYTPPESPVPSYASSTPLHVPVPR 25 0 P41212 P41212 ETV6 Transcription factor ETV6 2 IS(0.069)Y(0.053)T(0.857)PPES(0.973)PVPS(0.023)Y(0.012)AS(0.004)S(0.004)T(0.004)PLHVPVPR;IS(0.138)Y(0.097)T(0.773)PPES(0.991)PVPSYASSTPLHVPVPR;IS(0.06)Y(0.175)T(0.771)PPES(0.992)PVPS(0.001)YASSTPLHVPVPR;IS(0.045)Y(0.027)T(0.93)PPES(0.997)PVPS(0.001)YASSTPLHVPVPR;IS(0.172)Y(0.071)T(0.758)PPES(0.997)PVPS(0.002)YASSTPLHVPVPR;IS(0.067)Y(0.07)T(0.884)PPES(0.98)PVPSYASSTPLHVPVPR;IS(0.086)Y(0.206)T(0.721)PPES(0.985)PVPS(0.001)Y(0.001)ASSTPLHVPVPR 98.11200000000001 1.101e-05 34723800.0 25410.3 24654.4 59270.0 89322.7 75270.3 63526.7 43773.600000000006 76281.9 50554.0 64112.0 True False 33490.24683292619 32623.452656930713 58484.04107366996 68730.73153695826 64820.31810495282 59554.3654065101 47669.365599300465 64494.28513867793 53226.18123196348 61867.45839417407 0.5413224933138662 0.527311990886679 0.9453118423105819 1.1109351074203897 1.0477288026277933 0.9626121219829876 0.7705079024838264 1.0424589406561304 0.8603259712536644 1.0 15.916893146692564 -5.272314685367423 6.241598419699137 0.9707200343450827 0.5317319291758138 0.7807069064032696 0.09186157856720849 0.06302281592805706 11.806762443831687 0.02514215999824263 0.05797525708413564 5.341771597928484e-06 5.272314685367423 -0.4389881051692689 ISYT(ph)PPES(ph)PVPSYASSTPLHVPVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 ISYTPPESPVPSYASSTPLHVPVPR 25 0 P41212 P41212 ETV6 Transcription factor ETV6 2 IS(0.166)Y(0.453)T(0.526)PPES(0.849)PVPS(0.005)Y(0.001)ASSTPLHVPVPR;IS(0.019)Y(0.016)T(0.965)PPES(0.999)PVPSYASSTPLHVPVPR;IS(0.15)Y(0.134)T(0.726)PPES(0.99)PVPSYASSTPLHVPVPR;IS(0.198)Y(0.289)T(0.723)PPES(0.79)PVPSYASSTPLHVPVPR;IS(0.066)Y(0.185)T(0.771)PPES(0.97)PVPS(0.005)Y(0.001)AS(0.001)STPLHVPVPR;IS(0.062)Y(0.169)T(0.77)PPES(0.999)PVPSYASSTPLHVPVPR 101.05 7.509299999999999e-06 18108500.0 24521.7 30154.300000000003 41542.5 50358.3 60308.8 50953.100000000006 46028.9 37602.299999999996 42559.299999999996 35725.1 True False 28672.73948434826 33147.819621173905 42533.030750808604 47536.88771481142 48491.7235703432 48281.02973819388 41668.70937162231 36615.27946793012 43181.64924821474 42201.77783026401 0.679420179871813 0.7854602655484038 1.0078492645944184 1.1264190789782667 1.1490445678705155 1.1440520333617386 0.9873685781488708 0.867624099041447 1.0232187236730117 1.0 15.365016156038301 -5.185080623335973 2.795269550489064 1.045335907820022 0.6937204901419476 0.7040043941533622 0.08083570585815397 0.17308634779690474 2.5613886683821128 0.025159222547825606 0.08919812169119384 6.530093153793358e-06 5.185080623335973 -0.35161541767807436 ISYT(ph)PPES(ph)PVPSYASSTPLHVPVPR ddPTM_PC-9_Lapatinib_30min_R1 5 ISYTPPESPVPSYASSTPLHVPVPR 25 0 P41212 P41212 ETV6 Transcription factor ETV6 2 IS(0.126)Y(0.163)T(0.72)PPES(0.99)PVPSYASSTPLHVPVPR;IS(0.057)Y(0.064)T(0.887)PPES(0.992)PVPSYASSTPLHVPVPR;IS(0.084)Y(0.101)T(0.826)PPES(0.989)PVPSYASSTPLHVPVPR;IS(0.165)Y(0.078)T(0.759)PPES(0.998)PVPSYASSTPLHVPVPR;IS(0.365)Y(0.324)T(0.634)PPES(0.67)PVPS(0.004)Y(0.002)AS(0.001)STPLHVPVPR 111.31 1.0695999999999999e-06 29440700.0 58281.1 40098.7 72316.8 47904.6 64006.8 65208.5 57377.5 56308.7 79250.0 44743.799999999996 True False 57450.00082655522 40005.8539238068 66371.19185492069 51427.66408906095 60242.04586621051 62419.684463437865 60348.22619973631 58925.00776701568 70324.03046050314 52477.70621263408 1.0947506088351866 0.7623399879885628 1.264750246247267 0.9799907008260141 1.1479550120219841 1.189451463646676 1.1499783537643913 1.1228579147163524 1.3400743960789303 1.0 15.67941704104547 -5.269550128820357 24.99960646371912 1.1491217023773717 0.9285452932613107 0.3302538837865404 0.1257943909312974 578.5580359897349 1783282.4437374868 0.03080492299784177 0.06595604164731463 5.375883779323012e-06 5.269550128820357 -0.2205764091160609 ISYT(ph)PPESPVPSYASSTPLHVPVPR ddPTM_PC-9_AZD4547_30min_R2 2 ISYTPPESPVPSYASSTPLHVPVPR 25 0 P41212 P41212 ETV6 Transcription factor ETV6 1 IS(0.217)Y(0.002)T(0.78)PPES(0.001)PVPSYASSTPLHVPVPR;IS(0.054)Y(0.002)T(0.942)PPES(0.001)PVPSYASSTPLHVPVPR 140.71 1.7575e-08 53938000.0 40415.0 39179.0 132897.0 200891.0 130504.0 106641.0 91098.0 127484.0 88197.0 120308.0 True False 53266.129315777885 51842.845562897 131134.6989466429 154578.6836850102 112385.7722630145 99972.72141187315 99205.54551978999 107784.27709088527 92858.91336225592 116096.05353890543 0.45881085266974775 0.44655131662613945 1.1295362327083565 1.3314723366820451 0.9680412799333652 0.861120756170845 0.854512642727729 0.9284060379775548 0.7998455634940044 1.0 16.824959405842534 -5.252069039577759 24.815858410095096 0.9843699141699109 0.45268098332649837 0.6813066550934268 0.14538704002666786 377.6253949628379 1000075.1335074741 0.04207568666267302 0.108105560992442 5.596686241801649e-06 5.252069039577759 -0.5316889308434125 ISYT(ph)PPESPVPSYASSTPLHVPVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISYTPPESPVPSYASSTPLHVPVPR 25 0 P41212 P41212 ETV6 Transcription factor ETV6 1 IS(0.08)Y(0.012)T(0.899)PPES(0.008)PVPSYASSTPLHVPVPR 112.01 3.0034e-07 15188000.0 14581.0 19723.0 29806.0 36305.0 37217.0 32100.0 30074.0 27611.0 29410.0 22691.0 True False 17049.275312122798 21680.969095233933 30516.68807988448 34270.94855239807 29924.596014469906 30416.619491179597 27225.173003095206 26886.240506272723 29840.06561174634 26804.698678142842 0.6360554735884856 0.8088495735605148 1.1384827878989916 1.2785425780720816 1.1163936731313118 1.1347495398626508 1.0156865902505081 1.0030420721795457 1.1132401065220183 1.0 14.710198296855104 -5.094261729474246 3.2419298021819416 1.105099231810461 0.6570370834694662 0.789390309304085 0.08008642079490685 0.11597613228483862 2.235732822745018 0.023178032555529367 0.0861475668553839 8.048932225735047e-06 5.094261729474246 -0.4480621483409949 ISYT(ph)PPESPVPSYASSTPLHVPVPR ddPTM_PC-9_Lapatinib_30min_R1 2 ISYTPPESPVPSYASSTPLHVPVPR 25 0 P41212 P41212 ETV6 Transcription factor ETV6 1 IS(0.05)Y(0.001)T(0.934)PPES(0.015)PVPSYASSTPLHVPVPR;IS(0.065)Y(0.034)T(0.899)PPES(0.002)PVPSYASSTPLHVPVPR 145.43 2.9236000000000003e-06 36277000.0 84475.0 60546.0 110364.0 62897.0 84373.0 104244.0 67218.0 88745.0 96289.0 60689.0 True False 83270.37100918211 60405.80945693515 101290.29793736002 67522.65519824118 79410.34602370024 99785.72712463287 70698.21913980009 92868.41667955041 85443.91885187871 71179.01278699053 1.1698725192828403 0.8486463508240114 1.4230360041727492 0.9486315214894688 1.1156427002063474 1.4018981609544159 0.993245289188974 1.3047162786236912 1.2004088776501745 1.0 16.11916430316436 -5.241475767669609 24.996302114652142 1.1759596848846208 1.009259496046616 0.12538029223989022 0.17335705989339742 1628.079407102675 2038500.4998958837 0.041379215436851934 0.10915745855703202 5.73487864557202e-06 5.241475767669609 -0.16670018883800486 ISYTPPES(ph)PVPSYASSTPLHVPVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ISYTPPESPVPSYASSTPLHVPVPR 25 0 P41212 P41212 ETV6 Transcription factor ETV6 1 IS(0.033)Y(0.038)T(0.105)PPES(0.804)PVPS(0.011)Y(0.004)AS(0.002)S(0.001)T(0.001)PLHVPVPR 46.295 0.024247 4133900.0 5850.4 6764.0 7296.2 10297.0 10532.0 10429.0 8722.3 8451.5 9229.6 4397.8 True False 6840.757169332916 7435.485218281316 7470.169078992591 9720.092473324423 8468.330204594597 9882.08488079476 7896.060600016535 8229.657080104445 9364.565439312279 5195.086327034353 1.3167744939549453 1.4312534480107297 1.4379297298909337 1.8710165455273957 1.630065348582724 1.9021983964674576 1.5199094111154163 1.5841232584102978 1.802581295055803 1.0 12.34293200733336 -10.833001965111604 4.308567863017901 0.9993472269307876 1.6136485858585938 0.4913028316469513 0.18638735084114946 0.0012275298947512564 0.00019654912295587678 0.18921044717854085 0.04584340015093972 1.468919631007394e-11 10.833001965111604 0.6143013589278062 IT(ph)ESSLVEITEHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ITESSLVEITEHK 13 0 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 IT(0.363)ES(0.363)S(0.275)LVEITEHK 80.102 0.02754 954340.0 8167.5 11652.0 8319.9 7242.0 9129.0 6075.8 7931.9 4149.0 5186.7 6051.7 True False 9550.096434521838 12808.733554614697 8518.277969396462 6836.254218880789 7340.237983074827 5757.174352165391 7180.533010016986 4040.093146228878 5262.545675227636 7148.825304769154 1.335897301637898 1.7917256344297128 1.191563313725643 0.9562765807579825 1.0267754029711673 0.8053315204561847 1.004435372791482 0.5651408411859826 0.7361413170520288 1.0 12.803490482327202 -5.605181269139895 2.202285519752235 0.8493828157271948 1.5683478177922232 0.7184199880803415 0.17264524723973432 0.15526311054296177 1.5093516473518727 0.05066668452070803 0.11297793533529472 2.4820968925464697e-06 5.605181269139895 0.7189650020650284 IT(ph)LFNHMRTDT(ph)RGK ddPTM_PC-9_AZD4547_30min_R2 1 ITLFNHMRTDTRGK 14 2 A0A087WVA2;Q5TYW1-2;Q5TYW1 A0A087WVA2 ZNF658 Zinc finger protein 658 2 IT(0.968)LFNHMRT(0.035)DT(0.997)RGK 84.41 0.026523 0.0 15883.0 14385.0 15130.0 24108.0 26132.0 18538.0 23625.0 23160.0 18441.0 24728.0 True False 20933.463613076852 19034.669935993086 14929.366314233617 18550.273064887064 22504.02287115405 17378.815929457756 25727.579232310625 19581.15416385513 19415.753611952354 23862.28024661741 0.8772616613638283 0.797688642462882 0.6256470949103837 0.777388953325894 0.9430793134006589 0.7282965311716714 1.0781693520659086 0.8205902353623917 0.8136587707163747 1.0 14.542444291119988 -6.163035889808985 6.468822735825049 0.8886614446099074 0.7595529459380154 0.24222059285352027 0.10982263414126085 0.36942861701883173 20.588492505597756 0.032270944529803634 0.04185991864839045 6.870116634784115e-07 6.163035889808985 -0.129108498671892 IT(ph)NVPRS(ph)LGS(ph)AMRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ITNVPRSLGSAMRK 14 2 Q96RW7-2;Q96RW7 Q96RW7-2 HMCN1 Hemicentin-1 3 IT(1)NVPRS(1)LGS(1)AMRK 58.699 0.037915 10186000.0 34717.0 32168.0 36196.0 44515.0 45773.0 44593.0 46779.0 46906.0 43271.0 33300.0 True False 40593.90240799447 35361.426449094215 37059.04991409442 42020.96886957719 36804.10923422982 42254.46457851004 42347.75446936855 45674.76720101511 43903.75651431066 39337.026397345035 1.0319514748764607 0.8989349141927224 0.9420907808271863 1.068229419405563 0.9356098466231254 1.0741651936701018 1.0765367478876522 1.1611138762664028 1.1160924079730097 1.0 15.263600283684784 -6.878990849179996 5.1028050834793115 1.0983647468722182 0.9747201293472874 0.4621376787590934 0.059081294804809725 0.1801236663584275 7.311123085402265 0.02111574332005793 0.01862062275371117 1.3213234748946823e-07 6.878990849179996 -0.12364461752493083 IT(ph)PDGITK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ITPDGITK 8 0 Q14694;Q14694-3;Q14694-2;H3BQC6 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 IT(1)PDGITK 85.29 0.032609 7818400.0 45915.0 71483.0 64363.0 56238.0 57589.0 47225.0 61884.0 38303.0 46253.0 39427.0 True False 53687.50263741296 78579.35982531097 65897.6580180368 53087.16718605602 46304.84885609558 44748.43786513883 56021.89951863883 37297.58683538317 46929.362622920875 46574.80299603974 1.1527156141052923 1.6871646205780533 1.4148778691267914 1.139825909528163 0.994203858683694 0.9607864121066448 1.2028370688632302 0.8008104046850093 1.0076126919293955 1.0 15.507262046360214 -5.87559832113908 2.882886772953832 0.995722864039241 1.4513988319040318 0.6102572017914791 0.15092602688312864 0.16032343811969046 2.6811492435332944 0.04336755772427225 0.07040595962856283 1.3316855241835657e-06 5.87559832113908 0.4556759678647908 IT(ph)PDGITK ddPTM_PC-9_Lapatinib_30min_R1 3 ITPDGITK 8 0 Q14694;Q14694-3;Q14694-2;H3BQC6 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 IT(1)PDGITK;IT(1)PDGITK;IT(1)PDGITK 94.40899999999999 0.016485 51254900.0 250994.0 364885.0 333654.0 342726.0 376259.0 327369.0 359696.0 352278.0 323434.0 252712.0 True False 247414.77953333716 364040.131200968 306222.25606168556 367931.21334042 354128.1853736556 313368.19100441196 378319.29887395515 368646.12193406577 287005.45700898947 296392.9324824264 0.834752628752397 1.2282348575317412 1.0331631510135348 1.241362978053585 1.1947929473475296 1.0572728181465394 1.276411335808037 1.2437750078805383 0.9683276001394078 1.0 18.177151521290682 -4.752524249207696 24.993533623568172 1.1492750108116663 0.8347520241846449 0.40746503560161473 0.10901927461342346 325.99190363789506 913849.7348342544 0.025734262418728227 0.3043091786290909 1.767973498650209e-05 4.752524249207696 -0.3145229866270214 IT(ph)PEPAVSNTEEPSTTSTASNYPDVLTRPSLHR ddPTM_PC-9_AZD4547_30min_R2 2 ITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHR 33 1 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 IT(0.88)PEPAVS(0.077)NT(0.038)EEPS(0.002)T(0.001)T(0.001)S(0.001)T(0.001)ASNYPDVLTRPSLHR;IT(0.993)PEPAVS(0.006)NT(0.001)EEPSTTSTASNYPDVLTRPSLHR 90.744 4.8353e-12 17925500.0 10894.900000000001 12909.8 33961.0 51570.0 39423.0 46772.0 32425.0 64940.0 37401.0 43771.0 True False 14359.251572002195 17082.640385101404 33510.65495027682 39681.33324855759 33949.7969405138 43847.33944614298 35310.762184451756 54905.01517274404 39377.9405043452 42238.59061285551 0.3399557457684654 0.40443206407323223 0.7933658406698281 0.93945684912319 0.8037625415034806 1.0380871807024223 0.8359834377074307 1.299878011460767 0.9322740160833005 1.0 15.366274076230503 -5.0396263146018 0.7463481721954547 1.0271280175332969 4.217446724304087e-15 0.7766672006171749 0.1283806786967897 0.9168170690912816 0.4963065763340821 0.05338678475513345 0.7421998337299462 9.127959098818666e-06 5.0396263146018 -1.0271280175332926 down IT(ph)PEPAVSNTEEPSTTSTASNYPDVLTRPSLHR ddPTM_PC-9_Lapatinib_30min_R1 2 ITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHR 33 1 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 IT(0.965)PEPAVS(0.033)NT(0.002)EEPSTTSTASNYPDVLTRPSLHR;IT(0.992)PEPAVS(0.007)NTEEPSTTSTASNYPDVLTRPSLHR 84.87799999999999 1.3955e-11 13393700.0 26636.0 23694.0 61387.0 30557.0 49848.0 65483.0 35801.0 49083.0 66452.0 35570.0 True False 26256.16575555585 23639.137998755035 56339.99782067261 32804.26371516378 46916.03864493868 62682.44473832861 37654.60060436166 51363.57536630101 58967.475989417806 41718.227105954255 0.6293691649185261 0.5666381253143216 1.3504887846164357 0.7863292855626115 1.1245932988902725 1.5025193802970171 0.9025934996884704 1.2312022568900134 1.4134703241260616 1.0 15.348390228687206 -5.251243957671389 24.792700650591893 1.1600295785808914 0.5980035434854231 0.5281637146147713 0.21392284278703874 476.41653688594124 1158518.68596222 0.05409307761486084 0.13958657617480758 5.607329052040321e-06 5.251243957671389 -0.5620260350954683 IT(ph)PPAAKPGSPQAK ddPTM_PC-9_Lapatinib_30min_R1 1 ITPPAAKPGSPQAK 14 1 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 IT(1)PPAAKPGSPQAK 96.34200000000001 0.030633999999999998 27960000.0 29659.0 29204.0 27447.0 23550.0 30639.0 28928.0 25234.0 24989.0 26857.0 25316.0 True False 29236.057221205516 29136.379932288408 25190.413608483883 25281.94556049701 28836.87425859165 27690.816874461623 26540.493049089742 26150.08016682956 23832.081843252166 29691.836868550392 0.984649664843483 0.9812926044716915 0.8483952582659371 0.8514779894697475 0.9712054658745509 0.9326070662806231 0.8938649759726198 0.8807161470878125 0.802647608120706 1.0 14.857778727140609 -7.404763311898447 4.0751964270399235 0.8821801099208023 0.9253840960966808 0.0527395492848689 0.06356540886321894 0.6580454688901478 18.588690025874826 0.029156359515371665 0.018811551508541368 3.937646165366861e-08 7.404763311898447 0.043203986175878506 IT(ph)PVTVK ddPTM_PC-9_AZD4547_30min_R2 1 ITPVTVK 7 0 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2;S4R349;S4R3C2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 IT(0.957)PVT(0.043)VK 93.598 0.033761 13780000.0 150320.0 182580.0 161430.0 158820.0 156130.0 176570.0 159770.0 197280.0 166000.0 149190.0 True False 198118.63314976415 241595.41445350135 159289.33272351182 122206.50274453963 134454.04449997246 165529.04998728834 173989.22048449822 166794.9090434084 174774.4211042834 143966.903509902 1.376140128874395 1.678131630002617 1.1064302200023073 0.8488513662873515 0.9339232922428226 1.1497715513198024 1.2085362416128598 1.158564260097018 1.2139902772324505 1.0 17.135377663673047 -5.296288012461467 10.724799250188703 1.0769973736776182 1.5270075928095055 0.6516305552329696 0.13150249193185423 0.4502620809244538 137.93667995192058 0.03721210472286471 0.07805115999463526 5.054893238491155e-06 5.296288012461467 0.4500102191318873 IT(ph)SPLMEPSSIEK ddPTM_PC-9_AZD4547_30min_R2 1 ITSPLMEPSSIEK 13 0 P28066 P28066 PSMA5 Proteasome subunit alpha type-5 1 IT(0.581)S(0.418)PLMEPSSIEK 86.699 0.018254 3871600.0 20221.0 18495.0 30159.0 36347.0 35956.0 37792.0 28840.0 37066.0 36613.0 29983.0 True False 26650.85737707153 24473.147060562544 29759.07195445945 27967.7607055521 30964.13004573761 35428.86026572811 31406.70412951697 31338.30139194536 38548.28843307907 28933.304296114933 0.9211135065776126 0.8458469454471785 1.028540385498085 0.9666286442543487 1.0701899004980004 1.2245010076669804 1.0854862551504065 1.0831221028616964 1.332315453449788 1.0 14.820443473622287 -6.0170424854703475 1.0568133190815774 1.1498097929783297 0.8890785266891654 0.5204891667144853 0.0931064980822553 0.42116410090624434 0.9588187840735429 0.03710180621712809 0.0754427536158644 9.61518211907162e-07 6.0170424854703475 -0.2607312662891643 IT(ph)SPLMEPSSIEK ddPTM_PC-9_Lapatinib_30min_R1 2 ITSPLMEPSSIEK 13 0 P28066 P28066 PSMA5 Proteasome subunit alpha type-5 1 IT(0.5)S(0.5)PLMEPSSIEK;IT(0.631)S(0.369)PLMEPSSIEK 172.33 0.00019889 13481400.0 69000.0 62479.0 73533.0 59275.0 77436.0 77085.0 75276.0 69535.0 83294.0 67017.0 True False 68016.04734694959 62334.33371419833 67487.40058558833 63634.281235603405 72881.36672503351 73788.25424391156 79173.42295170319 72765.84994999776 73912.5525952954 78600.79915546069 0.8653353156425798 0.7930496176115244 0.8586095982574973 0.809588221994337 0.927234423925958 0.9387723157619476 1.0072852159570278 0.9257647597968787 0.9403537036450148 1.0 16.26225636037632 -6.41234265165533 3.093010238481036 0.9596628112566365 0.8305300262362708 0.792487514603726 0.03160619173539791 0.11455472499331042 2.0886674989642606 0.010150122598970572 0.011531665860491548 3.8695222510760704e-07 6.41234265165533 -0.12913278502036574 ITAHS(ph)SPPLTK ddPTM_PC-9_AZD4547_30min_R2 1 ITAHSSPPLTK 11 0 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 ITAHS(0.571)S(0.429)PPLTK 73.92699999999999 0.013328999999999999 25971000.0 93070.0 85729.0 115130.0 174590.0 138470.0 114530.0 97176.0 131070.0 102870.0 123040.0 True False 122664.32402373984 113439.22272803287 113603.3009753943 134340.97288861088 119245.83066618352 107368.42099475636 105824.4757451436 110816.14318896766 108307.4981867327 118732.40705046128 1.033115785916877 0.9554192115369243 0.9568011278261452 1.1314600303817302 1.0043242079266872 0.9042890956394473 0.8912855249381763 0.933326847672437 0.912198285853853 1.0 16.857354235110954 -6.710462394773291 6.567300183782864 0.9217975514581174 1.01664104501158 0.40306539656547635 0.05334314028486277 0.20625545924377445 19.730484781807245 0.01834720476839008 0.01815592322741335 1.9477696985277974e-07 6.710462394773291 0.09484349355346255 ITAHS(ph)SPPLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ITAHSSPPLTK 11 0 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 ITAHS(0.559)S(0.439)PPLT(0.002)K 60.345 0.036255 21400000.0 82400.0 80374.0 75770.0 97216.0 95467.0 80012.0 94479.0 85501.0 85753.0 65166.0 True False 96348.69252581589 88352.99954673884 77576.64415932528 91769.30269852467 76760.92666559355 75816.02986692406 85529.26515127442 83256.68934579789 87006.9753962627 76980.07994622797 1.2516055139604592 1.147738474790557 1.0077495920180133 1.19211752914036 0.9971531170039379 0.9848785545544118 1.1110571099824553 1.081535501183608 1.130253118170814 1.0 16.232197548983038 -4.925574730525091 3.1915160606342448 1.0671193851442107 1.2547916134821075 0.45295592192066714 0.06471097339899776 0.2544752576471846 4.669420015227174 0.01652216066435827 0.10000223016566778 1.1869304443216408e-05 4.925574730525091 0.18767222833789687 ITAHS(ph)SPPLTK ddPTM_PC-9_Lapatinib_30min_R1 2 ITAHSSPPLTK 11 0 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 ITAHS(0.568)S(0.431)PPLTK;ITAHS(0.573)S(0.427)PPLTK 73.877 0.0134 30685000.0 209299.0 155115.0 200653.0 165761.0 174914.0 163640.0 164342.0 156168.0 181677.0 141245.0 True False 206314.35787926443 154755.84074773727 184156.08488297858 177951.61690248575 164625.90241415513 156641.49866347137 172850.82462841817 163424.13539931315 161214.6231163766 165659.01005286814 1.245415856423515 0.9341830589132988 1.1116575236336816 1.0742042756726276 0.9937636495691765 0.9455658259305127 1.0434133620215094 0.9865091874396584 0.9731714747355236 1.0 17.337857146947734 -4.749683092611549 24.99985501359281 1.0107037179815301 1.245416379783974 0.64755745213554 0.05271419987529531 357.15656781941806 759449.4952856402 0.013479819807833039 0.21589790710250822 1.7795775051569014e-05 4.749683092611549 0.23471266180244377 ITAHSS(ph)PPLTK ddPTM_PC-9_AZD4547_30min_R2 3 ITAHSSPPLTK 11 0 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 ITAHS(0.357)S(0.642)PPLTK;ITAHS(0.06)S(0.939)PPLT(0.001)K;ITAHS(0.292)S(0.702)PPLT(0.006)K 96.82 0.0056464 31006300.0 155388.0 150556.0 221094.0 276502.0 223428.0 213432.0 188059.0 238375.0 190300.0 225850.0 True False 204798.15172881613 199220.28271695343 218162.1490997467 212758.73581331526 192408.87884801038 200086.06330003444 204795.8866814437 201539.6210625634 200358.86949484993 217943.0602433896 0.93968650114441 0.9140932613062909 1.0010052573186428 0.976212482176378 0.8828401263758354 0.9180657694564203 0.9396761083043264 0.9247352076156611 0.9193175009614787 1.0 17.733591740474004 -3.7121990178095614 13.6960322123662 0.9389868015703275 0.9448787328292283 0.0 0.037088315733596666 0.0 0.0 0.008618688593508573 0.0 0.00019399966598379688 3.7121990178095614 0.005891931258900751 ITAHSS(ph)PPLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ITAHSSPPLTK 11 0 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 ITAHS(0.019)S(0.98)PPLTK 82.515 0.007854 20685000.0 139940.0 134900.0 154730.0 158510.0 168990.0 162410.0 155180.0 158140.0 139170.0 111190.0 True False 163629.078059013 148291.98047695908 158419.35001679295 149629.198596354 135877.62260486538 153892.93369353501 140480.22699409173 153988.99256318033 141205.0979662274 131347.86682044461 1.245768827617867 1.1290018183521582 1.2061052368163363 1.1391825555941488 1.0344867099411141 1.1716439514309738 1.0695280433151706 1.172375283214052 1.075046754731524 1.0 17.003033244740436 -1.5228787464397955 0.04712167347193844 0.749176340688436 1.7990665702428152 0.5011584145093757 0.052468067118180015 497.5222348709932 1.7811892641849214 9.775947716158065 38.903768863336104 0.029999999919907483 1.5228787464397955 1.0498902295543793 ITAHSS(ph)PPLTK ddPTM_PC-9_Lapatinib_30min_R1 1 ITAHSSPPLTK 11 0 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 ITAHS(0.028)S(0.972)PPLTK 89.26 0.0053157 21457000.0 275360.0 233960.0 259700.0 272660.0 269950.0 262810.0 219610.0 206660.0 273060.0 204370.0 True False 271433.31590516085 233418.27999445927 238348.46847099042 292712.3259670958 254072.07174212037 251570.22894003274 230980.3312400172 216262.17804942123 242305.10735072574 239695.0821940927 1.1324108672591295 0.973813387649936 0.9943819718336487 1.2211861974292508 1.0599803275746222 1.0495427216830595 0.9636423456238508 0.9022386945523699 1.0108889391169051 1.0 17.870840784062253 -7.1861907220258345 3.396928121190419 0.960185967567424 1.072723313279054 0.3412335063978721 0.07016450322688002 0.29851058482831794 6.708772935453498 0.030376765917661714 0.022309900581697868 6.513422918707561e-08 7.1861907220258345 0.11253734571162988 ITDLYTDLR ddPTM_PC-9_Lapatinib_30min_R1 2 ITDLYTDLR 9 0 A0A087WUZ3;Q01082;Q01082-2;F8W6C1;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 ; 136.27 0.004659600000000001 3684900.0 21309.7 25576.0 24937.0 24867.0 26030.0 25316.0 25945.0 23944.0 25026.0 23719.0 False True 21005.819770279624 25516.780343384762 22886.776119603703 26695.802133880235 24498.96657694901 24233.293694478372 27288.305150140015 25056.525651869513 22207.308344536938 27818.797546419144 0.7550944549356882 0.9172495792029408 0.822709036269963 0.9596317773740921 0.8806623124550735 0.8711121914612625 0.9809304339846489 0.9007048421147451 0.7982842647127816 1.0 14.76377244100725 -4.134894437803458 1.8403489306020286 0.901963900947118 1.2247454719496198e-12 0.3288577251459296 0.062196333613474666 10.474727221479892 6.31859873832773 0.01604254553339412 29.48587231077082 7.330026794727868e-05 4.134894437803458 -0.9019639009458932 ITEAEKNER ddPTM_PC-9_AZD4547_30min_R2 1 ITEAEKNER 9 1 P15311;E7EQR4 P15311 EZR Ezrin 0 85.86200000000001 0.015694999999999997 18203000.0 29186.0 26503.0 39256.0 57577.0 49872.0 38119.0 27535.0 44403.0 37014.0 39560.0 False True 38466.5408934874 35069.57645558742 38735.43979058525 44303.512205782456 42948.13365338264 35735.41290403497 29985.561657636972 37541.536629432594 38970.484474421355 38175.01644112687 1.0076365246053034 0.9186525566969007 1.0146803695637607 1.1605368205697275 1.1250324860924898 0.9360942374221572 0.7854760640085225 0.9834059059890329 1.0208373985777124 1.0 15.220341157908239 -6.830026610966589 13.087560447865084 0.9340622046558735 1.042956985025625 0.24705180208162092 0.08628678802028808 1.4317321923725181 270.18607307678354 0.033668454157018905 0.029695990669531887 1.4790177600352813e-07 6.830026610966589 0.10889478036975153 ITEAEKNER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ITEAEKNER 9 1 P15311;E7EQR4 P15311 EZR Ezrin 0 ; 90.601 0.01095 14152400.0 58767.0 46714.0 56511.0 69593.0 81342.0 74542.0 65099.0 69162.0 62515.0 53616.0 False True 68715.09239884232 51351.457197929194 57858.43655916098 65693.92983355028 65403.61901843278 70632.88629630867 58932.3514440545 67346.57078319644 63429.163608239425 63336.15637597751 1.0849267832252758 0.8107763422380027 0.9135135421811901 1.0372263426213695 1.0326426919591134 1.1152063898070503 0.9304693372016286 1.0633195103190698 1.0014684697901433 1.0 15.950741698043268 -5.76195289541241 24.999987508905047 1.0284431812911303 0.9238426170342652 0.2164184312277141 0.07668983078334458 17.28794827619418 841727.2396241375 0.02037244972908179 0.03243690063615596 1.7300039892878783e-06 5.76195289541241 -0.10460056425686515 ITEFCHR ddPTM_PC-9_AZD4547_30min_R2 4 ITEFCHR 7 0 P07237;H7BZ94;I3L398;H0Y3Z3 P07237 P4HB Protein disulfide-isomerase 0 ;;; 183.89 3.0885000000000002e-09 29855000.0 111355.0 115059.0 157225.0 206371.0 153689.0 149895.0 126728.0 167938.0 123270.0 141594.0 False True 146763.5736721129 152249.5716486223 155140.09377101014 158795.3543501662 132351.93521524535 140522.04195415214 138006.54649533384 141987.04093132593 129785.80053930731 136636.83715785918 1.0741142485796427 1.1142644605621648 1.135419239774804 1.1621708878309798 0.9686402142222935 1.0284345340327536 1.0100244514288061 1.0391563789440292 0.9498595198699108 1.0 17.059986959678497 -6.263063174210138 24.99996602476606 1.003298031489107 1.1219707308434894 0.778208863570705 0.031901685018520004 69.64841667604288 1072303.0006135304 0.009754151193588405 0.01165411752544402 5.456784787465297e-07 6.263063174210138 0.11867269935438252 ITEFCHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 ITEFCHR 7 0 P07237;H7BZ94;I3L398;H0Y3Z3 P07237 P4HB Protein disulfide-isomerase 0 ;;;;; 175.75 4.7942e-06 27415000.0 149354.0 158836.0 162735.0 168224.0 195217.0 159954.0 168432.0 151793.0 148518.0 130421.0 False True 174636.68232403768 174604.18836944553 166615.21957592407 158798.95466956697 156965.63022696017 151565.73065707594 152476.90161792043 147808.59458797763 150689.7947815485 154065.2948879319 1.133523824759298 1.13331291447859 1.0814584796473539 1.030725023342073 1.0188253645387042 0.9837759423192993 0.9896901292976664 0.9593892946201451 0.9780904576281195 1.0 17.233182387996393 -5.708260953192896 0.891491378219251 0.9778829453262761 1.155444085874011 0.9603792627696925 0.012025363503716708 0.13309617122470674 0.18785572746085455 0.004978929357480377 0.01766397210123688 1.957668022057763e-06 5.708260953192896 0.17756114054773486 ITEFCHR ddPTM_PC-9_Lapatinib_30min_R1 4 ITEFCHR 7 0 P07237;H7BZ94;I3L398;H0Y3Z3 P07237 P4HB Protein disulfide-isomerase 0 ;;; 193.98 3.0885000000000002e-09 36008000.0 84021.5 91787.0 95957.0 80518.2 92528.0 94792.0 84993.0 83143.0 97135.0 70930.4 False True 82823.33800234405 91574.47284087639 88067.78586473165 86439.77702884104 87085.68495704712 90737.9671309447 89393.52166605709 87006.1273084441 86194.63342310388 83190.62513118301 0.9955849937627013 1.1007787559772861 1.058626326294073 1.0390567073217019 1.0468208986255603 1.0907234677929192 1.0745624464907284 1.0458645691295676 1.0361099377145424 1.0 16.3441333377379 -8.559311799735962 1.7443433660687462 1.0005350895614211 1.0594214789682126 0.2821210384810775 0.027716989015311787 0.5025676053413352 3.4228621921494327 0.025732987596270598 0.007349162604201053 2.758596623274471e-09 8.559311799735962 0.05888638940679147 ITES(ph)SLVEITEHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ITESSLVEITEHK 13 0 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 IT(0.009)ES(0.814)S(0.177)LVEITEHK 111.81 0.0002975 1818400.0 10161.0 16023.0 13627.0 11872.0 11591.0 7767.8 10433.0 7012.8 9096.5 10556.0 True False 11881.056611102107 17613.65754768206 13951.919360685291 11206.85032954331 9319.826756689712 7360.442893569625 9444.71071162108 6828.721430675793 9229.519103612742 12469.719238749984 0.9527926317844758 1.41251436463358 1.1188639530334679 0.8987251529062278 0.7473966797687075 0.5902653261588162 0.7574116570541051 0.5476243129400509 0.7401545236825995 1.0 13.606141362165067 -5.92071938300249 2.1693240219709384 0.7015574166745214 1.1991685845175577 0.6058510608466723 0.1546953848174382 0.17927303361487076 1.7115121158169568 0.04562814606553577 0.07594322584768336 1.2002746034962824e-06 5.92071938300249 0.4976111678430363 ITESEEVVSR ddPTM_PC-9_AZD4547_30min_R2 1 ITESEEVVSR 10 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 120.31 0.0033036999999999997 6420800.0 34257.0 28184.0 50273.0 53676.0 40857.0 39745.0 38901.0 39401.0 48318.0 43290.0 False True 45150.01341013496 37293.926831840756 49606.34717220532 41301.82748593325 35184.71079315556 37259.73886699207 42363.113638777395 33312.48079490741 50871.99083684795 41774.43027645053 1.0808050070664244 0.8927453129831058 1.1874811180888774 0.98868679267701 0.8422547132375905 0.8919269184622843 1.0140919542991045 0.7974371062502947 1.217778207870042 1.0 15.350332532361483 -5.9946400482728 24.99084230532483 0.9465847277419736 1.0460006235582495 0.08993846436910824 0.12719623709601 323.8177405784882 1509779.4164224446 0.03421667704034578 0.05057130488740798 1.0124182185625004e-06 5.9946400482728 0.09941589581627597 ITESEEVVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ITESEEVVSR 10 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ; 98.044 0.022629 7579400.0 51283.0 51050.0 48840.0 54256.0 62564.0 54196.0 56233.0 51167.0 45878.0 43752.0 False True 59964.199014580154 56117.906622303555 50004.53082673144 51216.21222032528 50305.03331943186 51353.86635339468 50906.203148335866 49823.920465917814 46548.878957351204 51683.891259358556 1.1602106101816059 1.0857910512328561 0.9675070821544802 0.9909511643253334 0.9733213210861513 0.9936145499512072 0.9849529884056114 0.9640125627517655 0.9006457877515649 1.0 15.657427073599088 -5.051309928468244 2.2887762576301856 0.9715182927324327 1.1665470096801995 0.8424305294911312 0.02700031248039213 0.13686830170438016 1.2201674325395455 0.00745789782493125 0.04259976153005179 8.885667777035822e-06 5.051309928468244 0.1950287169477668 ITESEEVVSR ddPTM_PC-9_Lapatinib_30min_R1 3 ITESEEVVSR 10 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ;; 150.35 0.00073724 27421800.0 126109.0 121656.0 121922.0 127373.0 125173.0 121399.0 102363.0 119224.0 125810.0 115662.0 False True 124310.66253444196 121374.3130065225 111898.04379253018 136740.43532387202 117810.57023958654 116207.047764891 107662.85527399434 124763.58228861069 111639.95296196727 135654.02259007274 0.9163802160890665 0.8947343446887565 0.8248781838977989 1.0080087026765308 0.8684635220556151 0.8566428443928438 0.7936576683710755 0.9197190021089797 0.8229756171649064 1.0 17.04957230336661 -6.4561496040205215 24.99999845805691 0.8676350145043662 0.9080055332974665 0.04739667152235638 0.06706580255620212 518.5793310664036 194284.285701312 0.01997159220827039 0.02264564654700561 3.4982464008188393e-07 6.4561496040205215 0.040370518793100274 ITFITS(ph)FGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGR 44 1 F5H0Q6;A0A0A0MQS2;Q8N2M8-3;Q8N2M8;Q8N2M8-4 F5H0Q6 CLASRP CLK4-associating serine/arginine rich protein 1 IT(0.016)FIT(0.18)S(0.485)FGGS(0.317)DEEAAAAAAAAAAS(0.001)GVTTGKPPAPPQPGGPAPGR 48.13 0.0005157 1415000.0 0.0 698.96 548.71 624.19 790.1 698.43 606.24 956.4 409.36 0.0 True False 0.0 768.3481295342858 561.7933273942634 589.2186579512837 635.2855767803067 661.8031012842541 548.8125584024884 931.2955133895638 415.34611556696655 0.0 0.0 ITFITSFGGS(ph)DEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGR 44 1 F5H0Q6;A0A0A0MQS2;Q8N2M8-3;Q8N2M8;Q8N2M8-4 F5H0Q6 CLASRP CLK4-associating serine/arginine rich protein 1 IT(0.001)FIT(0.029)S(0.088)FGGS(0.882)DEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGR 88.84299999999999 4.0500000000000005e-17 1461400.0 1194.9 2263.6 3035.0 3672.1 2163.6 2814.9 2879.5 3267.2 3147.5 2407.9 True False 1397.1729696492378 2488.3152483887616 3107.365910301597 3466.3641421088296 1739.6581115325548 2667.281688651759 2606.732914225332 3181.4394618845454 3193.5262330150144 2844.4332090740872 0.4911955623328002 0.8748017849217672 1.0924376428979674 1.218648457292197 0.6116009706196771 0.9377199225992745 0.9164331600086575 1.1184792287389163 1.1227285009988204 1.0 11.473925489769679 -4.798299179186662 3.256508533394571 0.9946720459864117 0.43070712212443907 0.4864725987320264 0.15761863967347411 0.2860497895356561 4.787258742378368 0.042119864096457585 0.4032600067946812 1.5911122552050187e-05 4.798299179186662 -0.5639649238619726 ITGCAS(ph)PGK ddPTM_PC-9_AZD4547_30min_R2 1 ITGCASPGK 9 0 P50991;P50991-2 P50991 CCT4 T-complex protein 1 subunit delta 1 ITGCAS(1)PGK 67.214 0.046353 10139000.0 144420.0 116640.0 165250.0 190940.0 198430.0 179760.0 168540.0 167710.0 163700.0 183830.0 True False 190342.55587738857 154341.59898048194 163058.677027568 146921.73299359286 170881.41965112157 168519.57878300358 183539.7334947573 141794.273092407 172352.84779982656 177394.16765349757 1.072992186807308 0.8700488918099946 0.919188489590419 0.8282218910408247 0.9632865719965648 0.9499724878901958 1.0346435619758583 0.7993175591283953 0.9715812536547528 1.0 17.43659905208201 ITGCAS(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ITGCASPGK 9 0 P50991;P50991-2 P50991 CCT4 T-complex protein 1 subunit delta 1 IT(0.018)GCAS(0.982)PGK 76.332 0.024669999999999997 15511000.0 138430.0 150480.0 136080.0 192320.0 170860.0 165810.0 177730.0 161680.0 148870.0 124920.0 True False 161863.46488287236 165418.65991232582 139324.66328627354 181544.93390985264 137381.2095287727 157114.63170817716 160894.12774622976 157436.07131412037 151046.9421156297 147567.00713382434 1.0968811255762811 1.1209731980422448 0.9441450768187224 1.2302542244094894 0.9309751020713294 1.0647002657287366 1.0903123324871624 1.0668785277412725 1.0235820665431636 1.0 17.171010675746736 -7.9882006238927525 0.009301178939612591 2.3592826454943907e-05 2.092827289202486 0.07810524904752869 0.08030396373401574 3247.11347271166 30.837915204838126 3470.3519821418317 3463.455180429789 1.0275415119853954e-08 7.9882006238927525 2.092803696376031 ITHS(ph)PDSVK ddPTM_PC-9_AZD4547_30min_R2 1 ITHSPDSVK 9 0 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 ITHS(0.997)PDS(0.003)VK 138.25 0.00089903 9938700.0 27061.0 18083.0 43540.0 57092.0 42525.0 46665.0 31631.0 45414.0 35434.0 36442.0 True False 35665.835096233226 23927.976117661678 42962.63115146937 43930.32146260711 36621.13778493135 43747.030173057836 34446.09772263355 38396.30980990139 37306.968900055275 35166.17667208152 1.0142084943953655 0.6804258632033243 1.2217032164766854 1.2492208599259942 1.0413738782699378 1.2440087127182258 0.9795235360339971 1.0918534069808128 1.0608764566002233 1.0 15.101900870723481 -5.269582467739772 24.997319355073877 1.1168450222184623 0.847317172819833 0.4382003157798383 0.11931369460699642 462.1330100537754 1418639.694294604 0.030108774617642515 0.06442381523036483 5.3754834891811526e-06 5.269582467739772 -0.2695278493986293 ITHS(ph)PDSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ITHSPDSVK 9 0 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 ITHS(0.99)PDS(0.009)VK 110.39 0.0023052 5631400.0 21495.0 25613.0 30851.0 33879.0 41211.0 30678.0 38031.0 32740.0 24420.0 25593.0 True False 25133.67895439817 28155.68936958002 31586.604843069024 31980.86946719997 33136.000385638836 29069.191674467536 34428.428359403915 31880.60969089744 24777.096301898862 30232.808305923485 0.8313378863145092 0.9312958652294139 1.0447790533861947 1.057820006120106 1.0960278664931875 0.9615114606727433 1.1387770534257113 1.0545037486527873 0.8195433269440705 1.0 14.883827375744687 -4.97001716852586 2.6054077778919638 1.0294420064533012 0.8245432444998689 0.3440289872410994 0.08243611243591366 0.36536020860376395 4.275877675330652 0.02159987382702386 0.13787324933877498 1.0714769467825724e-05 4.97001716852586 -0.20489876195343226 ITHS(ph)PDSVK ddPTM_PC-9_Lapatinib_30min_R1 2 ITHSPDSVK 9 0 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 IT(0.002)HS(0.994)PDS(0.004)VK;IT(0.002)HS(0.996)PDS(0.001)VK 118.28 0.0018074000000000002 15895600.0 106904.0 94822.0 108933.0 91482.0 111820.0 96005.0 85799.0 82675.0 110379.0 87559.0 True False 105379.52935620726 94602.4454848464 99976.94923354033 98209.89145500564 105242.9674465784 91899.08994858572 90241.25240226884 86516.38231992621 97946.95467760102 102693.45648496608 1.0261562222480496 0.9212120102189356 0.9735474163164093 0.9563403045975298 1.0248264207757538 0.8948874942391231 0.8787439384268833 0.8424722010656236 0.9537799002017239 1.0 16.647984732067158 -6.784291388211834 24.99199090934644 0.901929141851275 0.9754081636205886 0.2915267135348305 0.04974983942303389 264.7398575383102 289529.490151629 0.016845759301526975 0.014866569513105611 1.643268808373007e-07 6.784291388211834 0.07347902176931354 ITITNDKGR ddPTM_PC-9_AZD4547_30min_R2 1 ITITNDKGR 9 1 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;P11142;E9PKE3;E9PNE6;A8K7Q2;P54652;E9PS65;E9PM13;P17066 A0A0G2JIW1;P11142;P17066 HSPA1B;HSPA1A;HSPA8;HSPA2;HSPA6 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2;Heat shock 70 kDa protein 6 0 89.029 0.012523999999999999 27119000.0 41763.0 24975.0 57638.0 107820.0 86033.0 85154.0 74959.0 95150.0 63579.0 102500.0 False True 55042.765275636135 33047.680337255995 56873.68245999985 82963.76480239435 74088.80298767773 79829.30691860232 81630.20578517565 80446.75382948236 66939.65614089885 98911.5061985717 0.5564849570193984 0.3341136092995135 0.5749956162412692 0.838767581153186 0.7490412979753773 0.807078063884089 0.8252852364951087 0.8133204813197357 0.6767630856466067 1.0 16.593850736429296 -5.6093358427812445 3.8390776832636417 0.8049243097866804 0.4451360395726155 0.732395493026334 0.09242379156111392 0.10245072897693264 2.8964534678457614 0.023882548546581145 0.04431651594043801 2.458465721150077e-06 5.6093358427812445 -0.3597882702140649 ITITNDKGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ITITNDKGR 9 1 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;P11142;E9PKE3;E9PNE6;A8K7Q2;P54652;E9PS65;E9PM13;P17066 A0A0G2JIW1;P11142;P17066 HSPA1B;HSPA1A;HSPA8;HSPA2;HSPA6 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2;Heat shock 70 kDa protein 6 0 ; 109.44 0.0030704 42875000.0 115754.0 56929.0 69238.0 117708.0 131312.0 164535.0 135472.0 141303.0 143490.0 114736.0 False True 135348.8659542873 62580.53488934608 70888.89650657724 111113.20237448496 105582.35623107925 155906.4949526865 122639.1114276554 137593.94597290413 145588.26979359018 135536.72855032358 0.9986139358825786 0.4617238113882208 0.5230235174243328 0.8198014188694958 0.7789944272697822 1.1502896419312632 0.9048404276787645 1.0151783021811445 1.074161014145583 1.0 17.048324329095273 -6.413541495642207 1.9527801183943894 1.0204275948292931 0.6563253282915416 0.49676506859187 0.15441091839534984 0.269022838237248 2.03247837720103 0.054836292723050135 0.06418271363859614 3.8588553953222033e-07 6.413541495642207 -0.3641022665377516 ITITNDKGR ddPTM_PC-9_Lapatinib_30min_R1 2 ITITNDKGR 9 1 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;P11142;E9PKE3;E9PNE6;A8K7Q2;P54652;E9PS65;E9PM13;P17066 A0A0G2JIW1;P11142;P17066 HSPA1B;HSPA1A;HSPA8;HSPA2;HSPA6 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2;Heat shock 70 kDa protein 6 0 ; 119.75 0.002228 44121000.0 242610.0 111518.0 113176.0 88971.0 100906.0 100344.0 75360.0 61859.0 125156.0 69325.0 False True 239150.33691077481 111259.78692264571 103871.1061519938 95514.22413855522 94970.9074688289 96052.52103328882 79261.77206068799 64733.194967382035 111059.61332889268 81307.73388024398 2.941298760865886 1.3683788935320387 1.277505855777297 1.1747249564135633 1.1680427302119754 1.181345444638293 0.974836811679324 0.7961505244104559 1.3659169679045473 1.0 16.311104965552197 ITITNDQNR ddPTM_PC-9_Lapatinib_30min_R1 1 ITITNDQNR 9 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 114.89 0.0092684 7075100.0 37174.0 37660.0 38387.0 38471.0 43908.0 49362.0 46825.0 33278.0 32534.0 27559.0 False True 36643.891943123315 37572.800583823504 35230.96903810511 41300.28567549387 41325.41776644938 47250.90232844212 49249.36938351537 34824.21736731179 28869.67832179193 32322.53642994078 1.1336948145313128 1.1624335443247993 1.089981571046207 1.2777550971289766 1.2785326379327433 1.4618562633801535 1.5236851690232776 1.0773974203043566 0.8931749024203922 1.0 14.980252793954639 -7.991060192321094 24.69017885054548 0.9594869582319657 1.2734092861423294 0.5173172029321296 0.13027489643203888 141.74703946853617 391480.37107059144 0.08094193705831124 0.0387908307939663 1.0207979934024417e-08 7.991060192321094 0.3139223279103637 ITKPGS(ph)IDSNNQLFAPGGR ddPTM_PC-9_AZD4547_30min_R2 2 ITKPGSIDSNNQLFAPGGR 19 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 ITKPGS(0.999)IDS(0.001)NNQLFAPGGR;IT(0.06)KPGS(0.935)IDS(0.005)NNQLFAPGGR 107.63 0.00095975 26166600.0 35694.3 30285.2 49347.0 67143.0 77012.0 52398.0 45502.0 66054.0 49061.0 57049.0 True False 47044.34491243778 40074.29864063525 48692.62653724296 51664.218699009114 66320.21312388322 49121.54477676812 49551.58985094597 55846.87206991743 51654.26429998338 55051.731874364144 0.8545479553631418 0.7279389271910733 0.8844885506666065 0.9384667282932022 1.2046889510258343 0.8922797358831589 0.9000913897500941 1.0144435091954584 0.9382859092946564 1.0 15.748500329846904 -5.626563582562433 2.864413176637979 0.9876174651696734 0.7930703377694345 0.4382717552481793 0.08811803728603194 0.23993147544106483 3.9387641423562596 0.025610914921854758 0.050479477267813995 2.362851442311933e-06 5.626563582562433 -0.19454712740023894 ITKPGS(ph)IDSNNQLFAPGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ITKPGSIDSNNQLFAPGGR 19 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 IT(0.001)KPGS(0.992)IDS(0.008)NNQLFAPGGR 100.47 0.00021042 21323000.0 32066.0 22329.0 31824.0 34250.0 33577.0 29160.0 26491.0 29790.0 23646.0 19475.0 True False 37494.14046763115 24545.67555277994 32582.804853192087 32331.083539998202 26997.827884511287 27630.798266753813 23981.580701768813 29008.044065114078 23991.778016163 23005.66333598483 1.6297787166599034 1.0669405699937486 1.416294952131502 1.4053532414093362 1.173529643124092 1.2010433197783292 1.04242074447197 1.260908831076411 1.0428639968244564 1.0 14.489701434675192 -6.413954734742567 3.1160576624755447 1.1240974711040173 1.3597645216095344 0.4242362806048464 0.147834623237766 0.28797341070551646 5.324105876464186 0.04673389373271468 0.05303892999625871 3.8551853705365537e-07 6.413954734742567 0.23566705050551717 ITKPGS(ph)IDSNNQLFAPGGR ddPTM_PC-9_Lapatinib_30min_R1 2 ITKPGSIDSNNQLFAPGGR 19 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 IT(0.003)KPGS(0.996)IDSNNQLFAPGGR;ITKPGS(0.991)IDS(0.009)NNQLFAPGGR 123.59 9.7233e-05 22577900.0 50823.0 30427.0 38336.0 45624.0 36011.0 29067.3 28846.6 23173.1 36477.0 49299.0 True False 50098.25470020328 30356.54815092931 35184.16206123943 48979.34115720237 33892.903780350025 27824.159338185767 30340.13580050218 24249.806823560706 32368.576140161218 57820.26646321164 0.8664480080194455 0.5250157082939729 0.608509164924473 0.8470964274847411 0.5861768866443137 0.48121810984542923 0.5247318571215199 0.4193997763567855 0.5598136798756512 1.0 15.819287637002741 -10.577121874727315 4.750796495877585 1.0000117472165644 0.5955110819557554 0.42503351764554886 0.1386685824850481 204780598.81606326 0.3043249932504278 29112.309573714367 0.03498540915249511 2.6477570024197225e-11 10.577121874727315 -0.40450066526080897 ITKPGSIDS(ph)NNQLFAPGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ITKPGSIDSNNQLFAPGGR 19 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 ITKPGS(0.359)IDS(0.641)NNQLFAPGGR;ITKPGS(0.174)IDS(0.826)NNQLFAPGGR 103.14 0.0014744 9986100.0 30703.0 30712.0 35331.0 49623.0 45345.0 43377.0 35359.0 38774.0 32890.0 22804.2 True False 35900.411488108264 33760.88439146299 36173.42503356366 46842.78418993666 36459.972761806115 41102.23375915567 32009.539543008672 37756.2235844489 33370.95402823316 26938.420942052137 1.3326843308794705 1.253261446321847 1.3428190580055586 1.7388838154508486 1.3534561970145174 1.5257848204084286 1.1882485470052286 1.4015752321068553 1.2387865680775496 1.0 14.717377665916207 -8.743567072386659 0.7893213698169855 0.9990042585661104 1.4122790675569459 0.4251837368646493 0.14264705675087877 0.9686824304438789 1.2313423325892674 0.14570042906283875 0.05192802569812005 1.8048159800473382e-09 8.743567072386659 0.41327480899083546 ITKPGSIDSNNQLFAPGGRLS(ph)WGK ddPTM_PC-9_AZD4547_30min_R2 2 ITKPGSIDSNNQLFAPGGRLSWGK 24 2 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 ITKPGSIDSNNQLFAPGGRLS(1)WGK;ITKPGSIDSNNQLFAPGGRLS(1)WGK 74.525 9.6511e-05 52918000.0 52992.0 47005.0 87012.0 157751.0 143003.0 111323.0 78956.0 98433.0 75965.0 107224.0 True False 69842.35369792646 62198.44701712584 85858.16402736912 121383.94417865445 123149.50186145864 104361.95521172852 85982.93104196072 83222.44161531738 79980.35481437886 103470.12039644578 0.6750002167807041 0.6011247186995867 0.8297870312550478 1.1731304043483457 1.1901938587643592 1.0086192498072455 0.8309928577691522 0.8043137603053963 0.7729802044100667 1.0 16.65885468777097 -5.472064831342563 4.839356176702207 0.9683554673325027 0.6477145475498852 0.4871933367492416 0.13478149040096146 0.19944150591526638 10.164748411687686 0.04196745881751489 0.08754477940373064 3.3723696227431056e-06 5.472064831342563 -0.32064091978261744 ITKPGSIDSNNQLFAPGGRLS(ph)WGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ITKPGSIDSNNQLFAPGGRLSWGK 24 2 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 ITKPGSIDS(0.001)NNQLFAPGGRLS(0.998)WGK 59.818999999999996 0.0129 6184100.0 8252.0 6668.9 10179.0 15335.0 15199.0 14031.0 14119.0 15674.0 14693.0 12697.0 True False 9648.900615570767 7330.944318775314 10421.705964072475 14475.82966674079 12220.86505693442 13295.189659836169 12781.546107292055 15262.57410797576 14907.857328574937 14998.865590603298 0.6433086927331189 0.4887665853455016 0.6948329459396991 0.9651283011569763 0.8147859571853702 0.8864130143392663 0.8521675209423584 1.0175818974961464 0.9939323236495047 1.0 13.872565769023929 -5.6045392459718935 3.7589756206266514 0.9231653599389121 0.5685094120904298 0.8119445633181075 0.07287003624917196 0.09211980577461726 2.5311571130729993 0.020950959883019604 0.03916665025559758 2.485768922126152e-06 5.6045392459718935 -0.3546559478484823 ITKPGSIDSNNQLFAPGGRLS(ph)WGK ddPTM_PC-9_Lapatinib_30min_R1 1 ITKPGSIDSNNQLFAPGGRLSWGK 24 2 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 IT(0.001)KPGS(0.002)IDS(0.034)NNQLFAPGGRLS(0.963)WGK 44.106 0.019056 5347300.0 16300.0 8043.8 11701.0 11972.0 12332.0 9319.2 8321.9 8257.7 10991.0 6862.4 True False 16067.559010946094 8025.175075309596 10738.988947166177 12852.460817421248 11606.656005644836 8920.639540116244 8752.767262630572 8641.38288821595 9753.077839638998 8048.556696426777 1.9963279898468527 0.9970949299360018 1.3342751194054256 1.596865289291831 1.442079175611412 1.1083526993201944 1.0874952606740578 1.0736562111878225 1.2117797274098792 1.0 12.974514380486188 -6.763092627987428 7.41899943985723 1.0995371827133704 1.4466269974048198 0.38474546807430954 0.23722883637647404 0.15089660480051642 51.81962164969424 0.07957185621534554 0.07444597776227123 1.7254698379380268e-07 6.763092627987428 0.3470898146914494 ITLDNAYMEK ddPTM_PC-9_Lapatinib_30min_R1 1 ITLDNAYMEK 10 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 106.16 0.010858 28642000.0 69747.0 66661.0 67793.0 61619.0 57094.0 69302.0 63519.0 52124.0 57297.0 56894.0 False True 68752.39498996665 66506.65055013954 62219.32122854777 66150.66681495815 53735.843171122826 66338.11501085239 66807.70301914615 54545.87132801729 50843.608495841676 66728.05209351036 1.0303372095085204 0.996682031972692 0.9324312530711341 0.9913471881699307 0.8052961458521117 0.9941563245078467 1.0011936647802064 0.817435390614709 0.7619525357130345 1.0 16.026005769268053 -4.364365984143832 0.4509210446643312 0.8870427351061455 1.1969280371116982 0.2115625975132801 0.08364316461398982 11.79564627066604 1.405835798207881 0.060306313663603874 2.109479659722273 4.32149500996596e-05 4.364365984143832 0.30988530200555264 ITLPVDFVTADKFDENAK ddPTM_PC-9_AZD4547_30min_R2 2 ITLPVDFVTADKFDENAK 18 1 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 ; 152.94 3.6386e-05 14928000.0 116655.0 103921.0 120209.0 160153.0 150475.0 141023.0 130495.0 139633.0 139836.0 135868.0 False True 153748.86342526437 137511.43096408344 118614.95011683469 123232.20018918462 129584.14363756742 132204.80951666436 142108.80219768808 118055.92829713247 147227.44547914804 131111.30267500068 1.1726591093856933 1.0488144664762231 0.9046889756778482 0.9399052383351966 0.9883521938515187 1.0083402942336273 1.0838791110934811 0.9004252561639943 1.1229195536566068 1.0 17.00043253536105 -4.851276757890159 3.6244044202621293 0.99090203724171 1.180377519864596 0.39325880206513086 0.0671266603999658 0.23984834146457348 5.2783718784976275 0.016527537764596093 0.10841952922498137 1.4083910031203884e-05 4.851276757890159 0.18947548262288605 ITLPVDFVTADKFDENAK ddPTM_PC-9_Lapatinib_30min_R1 2 ITLPVDFVTADKFDENAK 18 1 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 ; 172.57 5.033e-08 20827900.0 119629.0 116712.0 113356.0 98250.0 114564.0 81494.0 109863.0 104989.0 89362.0 107226.0 False True 117923.0685227284 116441.76053476396 104036.30724681406 105475.63275239186 107825.57076148996 78008.69159179264 115551.16857621248 109867.17222118791 79297.11053642262 125759.8712303361 0.9376843930346098 0.9259055324690536 0.8272615598998655 0.8387065899519526 0.8573925029233015 0.6202987553073702 0.9188238461581612 0.8736266278450633 0.630543827380243 1.0 16.940312119923874 -5.250573228661498 1.6248957954285785 0.8100122917152764 0.9519194612051601 0.13297215327555212 0.11110746134745401 0.9456514375967808 4.137866618636884 0.031649551171947184 0.15793387747046325 5.61599576133224e-06 5.250573228661498 0.1419071694898837 ITNDFYPEEDGK ddPTM_PC-9_Lapatinib_30min_R1 2 ITNDFYPEEDGK 12 0 P55884;P55884-2;C9JZG1 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 0 ; 116.54 0.0024048999999999997 3757700.0 36052.0 42935.0 38915.0 34206.0 39078.0 39577.0 37943.0 39591.0 35847.0 30559.0 False True 35537.89186887292 42835.58664541852 35715.55891624406 36721.62334787095 36779.50887030402 37884.38396849306 39907.50288347517 41430.54239405135 31809.5333743553 35841.08243269201 0.9915406973439356 1.1951532637403428 0.9964977755154666 1.0245679219323958 1.0261829825975353 1.0570100397954854 1.1134569654367923 1.155951204092569 0.8875159792981201 1.0 15.129326588281335 -8.269847067943786 24.99252932536502 0.9437579913144466 1.0697983839918042 0.3519855699619139 0.0685400966766966 758.1974337128606 2253775.7891717358 0.06127102394528799 0.016882434637398334 5.372209395495305e-09 8.269847067943786 0.12604039267735756 ITPGNYGNT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 ITPGNYGNTPR 11 0 Q5VYS8-5;Q5VYS8-3;Q5VYS8-2;Q5VYS8-4;Q5VYS8-6;Q5VYS8 Q5VYS8-5 ZCCHC6 Terminal uridylyltransferase 7 1 ITPGNYGNT(1)PR;IT(0.002)PGNYGNT(0.998)PR 99.161 0.011434999999999999 4058400.0 18849.3 21133.7 32489.0 42080.0 34876.0 30061.0 23661.0 29364.0 23750.0 31484.0 True False 24842.985310203952 27964.755232971667 32058.1746320645 32379.106129519147 30034.06940358062 28181.280917867625 25766.783162569398 24826.468517592497 25005.37651341404 30381.75474298379 0.8176942220870592 0.9204456908279699 1.0551785077347402 1.0657418046927198 0.988556113945872 0.927572523584263 0.8481005583958198 0.8171505802615234 0.8230392459207333 1.0 14.890917576772342 -7.060074077767488 3.344200103490152 0.8573629706226271 0.9762987694107864 0.2313427952415893 0.08124974725532204 0.3330024009115124 7.355732243709572 0.034500749223318944 0.026989591113811415 8.708150420495558e-08 7.060074077767488 0.1189357987881593 ITPGNYGNT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 ITPGNYGNTPR 11 0 Q5VYS8-5;Q5VYS8-3;Q5VYS8-2;Q5VYS8-4;Q5VYS8-6;Q5VYS8 Q5VYS8-5 ZCCHC6 Terminal uridylyltransferase 7 1 ITPGNYGNT(1)PR 100.02 0.010563 4315400.0 18454.0 14581.0 20370.0 16425.0 16754.0 11104.0 12143.0 9618.8 12729.0 9415.8 True False 18190.842575950865 14547.238590353963 18695.257230473897 17632.94929219379 15768.562659631347 10629.107804688252 12771.705123844675 10065.724563155802 11295.325977687633 11043.308484235142 1.647227604111501 1.3172898874572645 1.692903649043426 1.5967089316906866 1.4278839246537154 0.9624930626416729 1.156510763244267 0.9114772604174837 1.022820832526073 1.0 13.43088483597094 -6.6662339299665065 4.01963721243974 1.0132156306415496 1.5510823280411294 0.8510022945419856 0.110864125288416 0.08225534110244412 2.4792907233308163 0.03756717534020318 0.03704183639024145 2.156582466784942e-07 6.6662339299665065 0.5378666973995798 ITPHT(ph)SPAPR ddPTM_PC-9_AZD4547_30min_R2 1 ITPHTSPAPR 10 0 A0A0C4DFZ9;Q58A45-2;Q58A45-4;Q58A45-3;Q58A45 A0A0C4DFZ9 PAN3 PAB-dependent poly(A)-specific ribonuclease subunit PAN3 1 ITPHT(0.5)S(0.5)PAPR 143.55 0.00027102 11289000.0 13861.0 17803.0 24086.0 30829.0 27437.0 25809.0 17768.0 32148.0 24575.0 24120.0 True False 18268.509673289565 23557.471593360093 23766.60390248716 23721.850353301954 23627.846147093765 24195.159150036427 19349.31757882309 27180.26528754812 25873.984329143157 23275.56614155663 0.7848792833731605 1.012111647471386 1.0210967053580633 1.0191739358360234 1.0151351852579933 1.0395089426777868 0.8313145837632907 1.1677595776723115 1.111637163701349 1.0 14.506528639049213 -4.760738858977593 5.32137261761316 1.0241800884790273 0.771881279210688 0.4377235708135647 0.08148453626113834 0.15727223347330307 13.190178477074072 0.020643227126508512 0.147260672065203 1.7348468466024664e-05 4.760738858977593 -0.25229880926833925 ITPHT(ph)SPAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ITPHTSPAPR 10 0 A0A0C4DFZ9;Q58A45-2;Q58A45-4;Q58A45-3;Q58A45 A0A0C4DFZ9 PAN3 PAB-dependent poly(A)-specific ribonuclease subunit PAN3 1 IT(0.001)PHT(0.793)S(0.206)PAPR;ITPHT(0.796)S(0.204)PAPR 136.01 0.00024017 19404600.0 31609.0 40321.0 42056.0 50506.0 58738.0 55303.0 47711.0 44487.0 42822.0 40108.0 True False 36959.77939379259 44323.80240779431 43058.774538268175 47676.31256266128 47228.71055426105 52402.81332463255 43191.46868227293 43319.26338787276 43448.190738735204 47379.26290524671 0.7800834611485633 0.9355105945070741 0.9088105617932674 1.0062696133118119 0.9968223998907129 1.1060284629043806 0.9116112415815986 0.9143085124499826 0.9170296892466813 1.0 15.53196813382162 -3.986376122364381 1.1287424636162926 0.9750148879444372 6.80573637420736e-14 0.4933132306640988 0.058160869915419154 7.697169582396654 2.1924948459890286 0.019105939957620482 13.726450283586322 0.00010318673660728307 3.986376122364381 -0.9750148879443692 ITPHT(ph)SPAPR ddPTM_PC-9_Lapatinib_30min_R1 2 ITPHTSPAPR 10 0 A0A0C4DFZ9;Q58A45-2;Q58A45-4;Q58A45-3;Q58A45 A0A0C4DFZ9 PAN3 PAB-dependent poly(A)-specific ribonuclease subunit PAN3 1 IT(0.006)PHT(0.886)S(0.108)PAPR;ITPHT(0.5)S(0.5)PAPR 112.02 0.0031686999999999996 25473000.0 44117.0 45427.0 43435.0 41608.0 43354.0 46269.0 42757.0 38406.0 47344.0 32921.0 True False 43487.88348993304 45321.81657252657 39863.94196394866 44667.99112021912 40804.00295724347 44290.18272830701 44970.74824839223 40190.48296799617 42011.6201655781 38611.35098552486 1.1262978989322687 1.1737951513148923 1.0324410036544276 1.1568616476788096 1.0567877558218728 1.1470767429223365 1.164702790773922 1.040898128197154 1.0880639784225103 1.0 15.236737413653579 -8.51659933160787 1.0958259295450141 1.0031561319643365 1.1188271239595102 0.3503031934623678 0.04824332191883775 0.5908305689702915 1.557628132627021 0.044341898091664646 0.014295491765882719 3.0436917588097916e-09 8.51659933160787 0.11567099199517372 ITPHTS(ph)PAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ITPHTSPAPR 10 0 A0A0C4DFZ9;Q58A45-2;Q58A45-4;Q58A45-3;Q58A45 A0A0C4DFZ9 PAN3 PAB-dependent poly(A)-specific ribonuclease subunit PAN3 1 IT(0.268)PHT(0.132)S(0.6)PAPR 72.289 0.03095 3594000.0 23372.0 27688.0 36705.0 33072.0 44088.0 38228.0 41022.0 34373.0 36193.0 34125.0 True False 27328.417981958308 30436.68165638276 37580.18640448767 31219.083060870664 35449.272888356136 36223.25638345211 37136.09918643915 33470.74517120395 36722.254154571085 40311.592366648634 0.6779295080530776 0.755035459268144 0.9322426676347134 0.7744443031900531 0.8793816073037272 0.8985816301670345 0.921226302565098 0.8303007449265539 0.9109601481521442 1.0 15.298907152420737 -3.7305326581144818 0.6215135265194183 0.8994182658124696 2.7723741286135704e-29 0.6060194567465234 0.057990934917055474 7.953393644368466 0.8663893212948227 0.025389355425202587 6.861913755019466 0.0001859804704207065 3.7305326581144818 -0.8994182658124696 ITPLSLQTQGS(ph)SHETLNIVEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ITPLSLQTQGSSHETLNIVEEK 22 0 O43491;E9PMV8;Q6R5J7 O43491 EPB41L2 Band 4.1-like protein 2 1 ITPLS(0.002)LQT(0.035)QGS(0.529)S(0.41)HET(0.023)LNIVEEK 78.429 0.00036925 12124000.0 8781.7 9698.8 18700.0 22005.0 26244.0 18153.0 19570.0 19651.0 21248.0 14901.0 True False 10268.26836351888 10661.632766863806 19145.878920144914 20772.131191172568 21101.67659413032 17201.02472346989 17716.187925469603 19135.182071955576 21558.711802733305 17602.43334374891 0.5833436868071091 0.6056908473196994 1.0876836484055836 1.180071572238011 1.1987931544489605 0.9771958448902991 1.0064624350224334 1.0870759569585864 1.2247574742493983 1.0 14.103487258997193 -5.259866373473434 6.1772210055534496 1.09855918374182 0.5901719808575749 0.8592829902634559 0.08107646675811918 0.0485247688288288 9.206080890665225 0.02235558878738934 0.05373607228801085 5.497099861526337e-06 5.259866373473434 -0.5083872028842451 ITPLSLQTQGSS(ph)HETLNIVEEK ddPTM_PC-9_AZD4547_30min_R2 2 ITPLSLQTQGSSHETLNIVEEK 22 0 O43491;E9PMV8;Q6R5J7 O43491 EPB41L2 Band 4.1-like protein 2 1 ITPLSLQT(0.047)QGS(0.166)S(0.783)HET(0.004)LNIVEEK;ITPLS(0.002)LQT(0.001)QGS(0.043)S(0.942)HET(0.012)LNIVEEK 98.32600000000001 7.0073e-05 12686000.0 11032.0 10755.7 22235.0 35728.0 31891.0 27318.0 21483.0 28641.0 21000.0 28419.0 True False 14539.946520145051 14232.269685822796 21940.149371909087 27491.46159209744 27463.485128730073 25609.801141489213 23394.945381914476 24215.1915547053 22110.01712765029 27424.059460070377 0.5301894324330545 0.5189702022979158 0.8000328836747929 1.0024577736977707 1.0014376306584771 0.9338442829289101 0.8530810479016675 0.882990776400656 0.8062269978608613 1.0 14.74315452212649 -5.374565685831296 3.2536972225398024 0.9207689789133281 0.5190371758161311 0.8605206306304226 0.06361714832548682 0.08896825970709692 1.7496000301022558 0.018743666833433523 0.0453561983690194 4.22118429985416e-06 5.374565685831296 -0.401731803097197 ITPLSLQTQGSS(ph)HETLNIVEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ITPLSLQTQGSSHETLNIVEEK 22 0 O43491;E9PMV8;Q6R5J7 O43491 EPB41L2 Band 4.1-like protein 2 1 ITPLS(0.004)LQT(0.069)QGS(0.178)S(0.569)HET(0.179)LNIVEEK;IT(0.001)PLS(0.005)LQT(0.022)QGS(0.118)S(0.765)HET(0.089)LNIVEEK;ITPLS(0.001)LQT(0.001)QGS(0.079)S(0.754)HET(0.165)LNIVEEK 73.51899999999999 0.0006228 30448800.0 21898.3 26604.2 54318.0 69128.0 81344.0 68107.0 59921.0 62095.0 62849.0 49713.0 True False 25605.249678860073 29245.28915496743 55613.14712216211 65254.98227599982 65405.22713278988 64535.349024478826 54244.84908952809 60465.07204509092 63768.04772637356 58725.573372108505 0.43601532021858797 0.4979992101508774 0.9470004961854552 1.111185102655676 1.1137435256418262 1.0989309310878461 0.9237006294653137 1.029620803563045 1.0858650510283474 1.0 15.841701273730886 -5.2893713347499745 3.1736386922986504 1.051718590986328 0.4412131337131983 0.9451113593933053 0.05568390561902238 0.0526294607401982 1.0753682263631514 0.016256697756966417 0.04447405557268323 5.1360431676004295e-06 5.2893713347499745 -0.6105054572731297 down ITPLSLQTQGSS(ph)HETLNIVEEK ddPTM_PC-9_Lapatinib_30min_R1 4 ITPLSLQTQGSSHETLNIVEEK 22 0 O43491;E9PMV8;Q6R5J7 O43491 EPB41L2 Band 4.1-like protein 2 1 ITPLS(0.001)LQT(0.009)QGS(0.249)S(0.667)HET(0.074)LNIVEEK;ITPLSLQT(0.011)QGS(0.096)S(0.877)HET(0.016)LNIVEEK;IT(0.022)PLS(0.118)LQT(0.081)QGS(0.186)S(0.521)HET(0.073)LNIVEEK;ITPLSLQT(0.001)QGS(0.232)S(0.742)HET(0.026)LNIVEEK 88.27799999999999 0.00012132 38307400.0 130130.0 81293.5 166056.0 96546.0 134594.0 141283.0 86998.0 96959.0 157499.0 91610.0 True False 128274.3223370809 81105.2698954077 152403.51667469658 103646.31490801448 126677.44554198538 135240.65543675906 91502.33075551662 101464.06910623188 139759.80408200365 107444.66643734803 1.1938640287173197 0.7548561746682971 1.4184372452174205 0.9646483007925907 1.179001710762927 1.25870050064904 0.8516228286573208 0.9443378854491257 1.300760742400358 1.0 16.71323434347177 -7.251105957450286 24.742812599889465 1.0195418458148515 1.1193394086158028 0.061499134622964524 0.19700007935634148 2071.092957700307 4959126.395554395 0.07405419407853277 0.05665881627186178 5.6091111046257e-08 7.251105957450286 0.09979756280095131 ITPLSLQTQGSSHET(ph)LNIVEEK ddPTM_PC-9_AZD4547_30min_R2 1 ITPLSLQTQGSSHETLNIVEEK 22 0 O43491;E9PMV8;Q6R5J7 O43491 EPB41L2 Band 4.1-like protein 2 1 ITPLSLQTQGS(0.01)S(0.148)HET(0.842)LNIVEEK 89.882 0.00043222 22839000.0 18279.0 17575.0 66375.0 127590.0 98970.0 106340.0 62808.0 80499.0 66650.0 89546.0 True False 24091.34177318085 23255.775052143108 65494.8241313454 98176.09674584957 85229.72384655297 99690.54298945595 68397.7903247816 68059.72923299545 70172.98293132814 86411.0217956812 0.27879940860026875 0.2691297310096781 0.7579452571016677 1.136152480385973 0.9863293139627326 1.1536785576401836 0.7915401172608296 0.7876278722166096 0.8120837072989613 1.0 16.398927720593626 -5.357053374209284 3.430257600212252 0.9469753385954983 0.26414433087078426 0.8209484675272578 0.12469114991796477 0.09991550876485368 2.191192888212473 0.03695088814173563 0.08898833871099049 4.394875996821677e-06 5.357053374209284 -0.6828310077247141 down ITPPAAKPGS(ph)PQAK ddPTM_PC-9_AZD4547_30min_R2 2 ITPPAAKPGSPQAK 14 1 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 IT(0.316)PPAAKPGS(0.684)PQAK;IT(0.001)PPAAKPGS(0.999)PQAK 97.76700000000001 0.012646 295165000.0 309910.0 257628.0 339818.0 459885.0 380435.0 357366.0 340287.0 369068.0 306146.0 320923.0 True False 408454.9334715502 340901.2128098737 335311.79128686356 353865.61840242206 327618.16703610495 335019.8475265181 370571.8837767314 312037.0209389324 322328.2525505541 309687.5834513582 1.3189257667984777 1.1007907033619193 1.0827421220764897 1.142653555750332 1.0578989424920326 1.0817994179580621 1.1965991004445167 1.0075864762202944 1.0408174876057998 1.0 18.2404540154983 -4.759712478651551 4.572558018446936 1.0831815845780148 1.338455969297338 0.6228002514821847 0.05609973221650172 0.13633224576766098 6.42831649413791 0.013921749075457363 0.11485471178388129 1.7389517074533146e-05 4.759712478651551 0.25527438471932307 ITPPAAKPGS(ph)PQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ITPPAAKPGSPQAK 14 1 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 ITPPAAKPGS(1)PQAK 67.153 0.016502 246410000.0 91247.0 80484.0 98769.0 110400.0 120040.0 96124.0 107960.0 101520.0 93836.0 89123.0 True False 106693.3148896008 88473.91961977429 101124.02754351836 104214.64592162907 96519.02371435025 91083.088223369 97733.2472372868 98855.20756933115 95208.17397972883 105280.29440272044 1.0134215096461952 0.8403654275636991 0.9605218917482939 0.989877987261177 0.9167814761720138 0.8651484946931857 0.9283147220640883 0.9389716103109296 0.9043304306837944 1.0 16.683875902938247 -10.958141626706944 5.734059636311179 1.000042259734432 0.9268583018318112 0.1559914179218208 0.049643655563512114 2.6121924134596212e-05 2.5726945034326043e-06 0.046816371762151004 0.01134808473306255 1.1011801478282199e-11 10.958141626706944 -0.07318395790262089 ITPPAAKPGS(ph)PQAK ddPTM_PC-9_Lapatinib_30min_R1 1 ITPPAAKPGSPQAK 14 1 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 IT(0.001)PPAAKPGS(0.999)PQAK 52.071000000000005 0.043498 253880000.0 75728.0 66196.0 74246.0 66058.0 60857.0 57123.0 61128.0 54562.0 62468.0 52014.0 True False 74648.10483318561 66042.72722907003 68141.78047784821 70916.12568302805 57277.51090946545 54679.9824502168 64292.90873839887 57097.149708373894 55432.19602279766 61004.55059570151 1.2236481394298715 1.0825868985866034 1.1169950407379872 1.1624727170439138 0.9389055463921624 0.8963262890435856 1.053903489339516 0.9359490259468785 0.9086567392351794 1.0 15.896629243159154 -6.2627986822884845 24.982501457526936 0.9543700987056563 1.1397635999909346 0.7480430471163437 0.05419056528579246 62.75712779027482 1153402.479112412 0.016459353091258948 0.019700102348145676 5.460109064268713e-07 6.2627986822884845 0.18539350128527832 ITPSYVAFTPEGER ddPTM_PC-9_AZD4547_30min_R2 1 ITPSYVAFTPEGER 14 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 147.58 0.00094924 3492600.0 10173.0 12852.0 18077.0 25512.0 20492.0 16404.0 13499.0 15030.0 12323.0 15077.0 False True 13407.802388455006 17006.157665442017 17837.28716869802 19630.602556470847 17647.03951766758 15378.255286806845 14700.384848971915 12707.458855040702 12974.368622096885 14549.158819081642 0.9215517237237307 1.1688756633227448 1.226001268561582 1.3492603112370143 1.2129250726525151 1.0569858696323955 1.0103941424910377 0.873415364630875 0.8917607391212629 1.0 13.828648123568176 -7.173066124174991 1.985084950619471 0.919380776383097 1.1855064893222955 0.5091685961990933 0.10707584531798482 0.28008547788191346 2.163806777337291 0.0554614132656554 0.0377788341560152 6.713266312743597e-08 7.173066124174991 0.2661257129391985 ITPSYVAFTPEGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ITPSYVAFTPEGER 14 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 111.5 0.0037167000000000003 0.0 1524.4 4435.2 1925.3 4202.1 4429.4 2034.4 2608.8 1901.1 2421.9 2539.0 False True 1782.4508117275911 4875.497344784338 1971.206453740911 3966.669960392012 3561.4908667139507 1927.7124826434813 2361.6755779236137 1851.1981393819524 2457.3157057153508 2999.300601287059 0.5942888188542043 1.6255447495633366 0.657222037996134 1.3225316457742966 1.1874404536796495 0.64272066688356 0.787408763533129 0.6172099384061627 0.8192962401504097 1.0 11.550410406486304 -6.759614114943742 24.995166930167155 0.7502828297343401 1.0981323303274455 0.2041285356665694 0.29707457587549213 67.12506731544491 919213.6564520494 0.09341152930689496 0.0888973942107081 1.7393456086351935e-07 6.759614114943742 0.3478495005931054 ITPSYVAFTPEGER ddPTM_PC-9_Lapatinib_30min_R1 4 ITPSYVAFTPEGER 14 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 ;;; 236.22 3.1052999999999995e-26 33822700.0 29987.4 20314.800000000003 23984.0 27654.0 20087.199999999997 27834.0 27906.1 25151.799999999996 24806.600000000002 18167.4 False True 29559.774176984334 20267.7623287376 22012.128100917325 29687.767411039666 18905.71038895468 26643.604704223064 29350.94131240401 26320.444449160183 22012.61948292137 21307.610883461162 1.3872871218954186 0.9511982567913944 1.0330641112844334 1.393294047531304 0.8872749972935341 1.2504266597483094 1.377486264083508 1.2352602360309644 1.0330871726218462 1.0 14.37908121951146 -8.362901015047019 5.426452142552284 1.0050636036854075 1.1810039804418944 0.138617000464053 0.17182699173237398 0.49267971309168096 20.4217647812791 0.1643220507628898 0.04284780275218451 4.336096960014867e-09 8.362901015047019 0.17594037675648688 ITS(ph)PLMEPSSIEK ddPTM_PC-9_AZD4547_30min_R2 5 ITSPLMEPSSIEK 13 0 P28066 P28066 PSMA5 Proteasome subunit alpha type-5 1 IT(0.068)S(0.928)PLMEPS(0.003)S(0.001)IEK;IT(0.024)S(0.976)PLMEPSSIEK;IT(0.025)S(0.968)PLMEPS(0.005)S(0.001)IEK;IT(0.033)S(0.966)PLMEPS(0.001)SIEK;IT(0.177)S(0.821)PLMEPS(0.001)S(0.001)IEK 167.73 7.8255e-05 213484400.0 997820.0 946979.0 1259609.0 1664017.0 1397182.0 1395450.0 1217014.0 1506106.0 1290371.0 1399807.0 True False 1315106.0040546693 1253071.4425663396 1242905.761646101 1280403.589456372 1203207.3964168348 1308192.2909031103 1325325.888331483 1273371.9245728464 1358577.3767153933 1350800.18299809 0.9735755299764635 0.9276512235770932 0.9201255502405113 0.9478852650245624 0.8907367733296613 0.9684572946974201 0.9811413301632317 0.9426797098491708 1.0057574716195565 1.0 20.365382849229654 -6.975028597925784 24.927411456919376 0.9772152832735683 0.9317389374531885 0.47229161124879515 0.025269906026620156 202.80515595787574 202447.26845030542 0.008581593407674669 0.007568004171302738 1.0591839765082723e-07 6.975028597925784 -0.04547634582037985 ITS(ph)PLMEPSSIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 ITSPLMEPSSIEK 13 0 P28066 P28066 PSMA5 Proteasome subunit alpha type-5 1 IT(0.019)S(0.981)PLMEPSSIEK;IT(0.099)S(0.901)PLMEPSSIEK;IT(0.003)S(0.996)PLMEPSSIEK;IT(0.097)S(0.903)PLMEPSSIEK 138.02 5.4803000000000004e-05 162619000.0 391160.0 438350.0 455441.0 567692.0 544943.0 513813.0 537831.0 538203.0 476405.0 405095.0 True False 457375.66223784175 481866.49104577437 466300.4407096108 535886.0577222952 438165.3310560563 486867.74176390836 486883.75412075885 524075.74152321497 483371.5218552871 478535.5167697446 0.9557820604941968 1.006960767088961 0.9744322508332838 1.1198459444341426 0.9156380575757492 1.0174119259744998 1.0174453871415174 1.0951658197930225 1.0101058435916876 1.0 18.868266479536885 -7.354070484912243 3.3402424567539417 1.041125993746095 0.999171035129145 0.07535201645803324 0.05492958643595217 0.6043839738971932 12.853834162602082 0.0244062628075738 0.015750285740545374 4.4251654720130875e-08 7.354070484912243 -0.04195495861695009 ITS(ph)PLMEPSSIEK ddPTM_PC-9_Lapatinib_30min_R1 7 ITSPLMEPSSIEK 13 0 P28066 P28066 PSMA5 Proteasome subunit alpha type-5 1 IT(0.021)S(0.979)PLMEPSSIEK;IT(0.125)S(0.875)PLMEPSSIEK;IT(0.018)S(0.982)PLMEPSSIEK;IT(0.165)S(0.834)PLMEPSSIEK;IT(0.015)S(0.985)PLMEPSSIEK;IT(0.415)S(0.584)PLMEPS(0.001)SIEK;IT(0.032)S(0.968)PLMEPSSIEK 145.0 6.559300000000001e-05 157418500.0 801420.0 729482.0 811889.0 681936.0 930301.0 935054.0 858664.0 866277.0 974414.0 811417.0 True False 789991.6038375705 727792.9292482416 745138.6204021694 732087.8483118091 875582.5242221383 895063.9201373358 903121.4204447796 906527.3919196703 864665.2342856876 951669.3473048072 0.8301114311130026 0.764753988672012 0.7829805830275537 0.7692670257638665 0.9200490976218243 0.9405198587852158 0.9489865603031992 0.9525655044864249 0.9085773716832204 1.0 19.86010087794375 -6.331764474773579 4.273825116817699 0.9452938828872585 0.7846243189381326 0.8915926496586704 0.027135196948512408 0.06594210392727658 2.344513070896064 0.008246170409887626 0.00954599009933669 4.6583865719700006e-07 6.331764474773579 -0.1606695639491259 ITS(ph)PNIR ddPTM_PC-9_Lapatinib_30min_R1 1 ITSPNIR 7 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 IT(0.223)S(0.777)PNIR 88.177 0.017446 7591800.0 34082.0 41847.0 46819.0 47199.0 52639.0 41523.0 48961.0 36108.0 49357.0 42540.0 True False 33595.984430126686 41750.105842572026 42969.72254656638 50670.17191124838 49542.87751225581 39747.15808484064 51495.96101198713 37785.70949873474 43797.894907748334 49892.98231901301 0.6733609190830845 0.8367931500992288 0.8612378043833964 1.01557713241646 0.992982884756845 0.7966482707066792 1.032128339868015 0.7573351550150874 0.8778367792830458 1.0 15.606549287586027 -4.739052768776421 1.6922837714249712 0.9150399089358103 0.573052845588233 0.4123896512167129 0.08920239685936832 1.1048315048830686 2.9007630218804556 0.024676682668193874 0.641410093986874 1.8236741040684768e-05 4.739052768776421 -0.34198706334757734 ITS(ph)PSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ITSPSLK 7 0 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 IT(0.119)S(0.865)PS(0.017)LK 69.598 0.046141 3301900.0 49331.0 57187.0 50375.0 57244.0 67505.0 52327.0 55564.0 45844.0 46180.0 42167.0 True False 57681.76396833758 62864.14742428351 51576.13104825137 54036.804267552005 54277.87983869717 49582.880003581144 50300.57567147643 44640.64357573309 46855.29513602332 49811.54330621168 1.157999936154246 1.2620397452420256 1.0354252774541046 1.0848249357657107 1.0896646888659747 0.9954094314800718 1.0098176513475696 0.8961907343707265 0.9406513435647816 1.0 15.604192490132842 -5.884576439324989 0.5289346337207581 0.9409652014048348 1.2482616186894004 0.7017929556863407 0.05522040506392906 0.8333081935722553 0.38838248861955305 0.04048012001448105 0.14028043613500377 1.3044383567818876e-06 5.884576439324989 0.3072964172845657 ITSFPESEGYSYETSTK ddPTM_PC-9_Lapatinib_30min_R1 1 ITSFPESEGYSYETSTK 17 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 0 173.06 1.6641e-24 0.0 6997.6 8021.4 11487.0 8411.3 8741.2 10686.0 11564.0 9964.7 11701.0 7633.6 False True 6897.812940797326 8002.826941133347 10542.583201102292 9029.895061274246 8227.059801860416 10228.984690282656 12162.727336913444 10427.69633992583 10383.110163007546 8953.057588867367 0.7704421503302263 0.8938652367303457 1.1775399740767236 1.0085822604896928 0.9189106313903656 1.1425130005867308 1.3584998439010516 1.16470783711836 1.1597278426890016 1.0 13.128164750834936 -6.861838124006512 5.282734805120071 1.1926168259588539 0.9665628810629531 0.4058460330079945 0.1262411772818246 0.21692785201415832 9.449273756463793 0.046729453864023086 0.04130578697722299 1.374554221602574e-07 6.861838124006512 -0.2260539448959008 ITSFVIPEPS(ph)PTSQTIQEGSR ddPTM_PC-9_AZD4547_30min_R2 1 ITSFVIPEPSPTSQTIQEGSR 21 0 P41214-2;P41214 P41214-2 EIF2D Eukaryotic translation initiation factor 2D 1 ITSFVIPEPS(0.472)PT(0.472)S(0.042)QT(0.014)IQEGSR 132.67 6.684899999999999e-07 0.0 8684.0 9490.6 11996.0 18267.0 14757.0 11742.0 10672.0 14451.0 10686.0 13576.0 True False 11445.331361579005 12558.250851201668 11836.925201952841 14055.825372336662 12708.24527436172 11007.770883789677 11621.787325596577 12217.930000944318 11250.840144098616 13100.708372212792 0.8736421753998496 0.9585932679669673 0.9035332186356814 1.072905752344638 0.970042604819484 0.8402424182754628 0.8871113679812097 0.932615981808977 0.8587963203548724 1.0 13.677357201804428 -6.724916834889509 24.99940841624778 0.8985015131764705 0.9595102212641892 0.1405525097606909 0.06327967806188067 306.4267117898404 209745.98762609024 0.020863126816500672 0.020862557367077525 1.8840098329284977e-07 6.724916834889509 0.06100870808771863 ITSPLMEPS(ph)SIEK ddPTM_PC-9_AZD4547_30min_R2 1 ITSPLMEPSSIEK 13 0 P28066 P28066 PSMA5 Proteasome subunit alpha type-5 1 ITSPLMEPS(0.5)S(0.5)IEK 113.24 0.0011984 0.0 18812.0 20802.0 24740.0 22543.0 27784.0 23238.0 23052.0 25573.0 25180.0 24942.0 True False 24793.82468609215 27525.839694718685 24411.931435171166 17346.059635878093 23926.671186749758 21784.924186467768 25103.583342358717 21621.280459078902 26510.963394011156 24068.78817175394 1.030123515532414 1.1436321387805386 1.0142567735844683 0.7206868709840015 0.994095382617935 0.9051109690696264 1.0429932393446866 0.8983119675486062 1.1014664803574634 1.0 14.554875885607293 -5.52259866642936 24.999936070489596 0.9447480823943603 1.0848945167666872 0.22447545724963702 0.10004074587505525 12.580824161231508 1122966.412009183 0.02646627802443559 0.046500702959511565 3.0019353401499395e-06 5.52259866642936 0.140146434372327 ITSPLMEPS(ph)SIEK ddPTM_PC-9_Lapatinib_30min_R1 1 ITSPLMEPSSIEK 13 0 P28066 P28066 PSMA5 Proteasome subunit alpha type-5 1 ITSPLMEPS(0.568)S(0.432)IEK 90.412 0.023328 0.0 20714.0 22414.0 19727.0 19443.0 21623.0 18602.0 19308.0 16897.0 16448.0 19363.0 True False 20418.614561517632 22362.101760112047 18105.122208422126 20872.90307994665 20351.17765245366 17806.435823379936 20307.673765230425 17682.096305531188 14595.453034881482 22709.868750424303 0.8991075547777501 0.9846865257508035 0.7972358804620505 0.9191115681616023 0.8961380568116858 0.7840836078388717 0.8942224188262209 0.7786084763348015 0.6426920910588172 1.0 14.471031747696445 -6.745264983542182 1.085252046848567 0.8014836177578599 0.9069586513902844 0.11701973124588261 0.09683423900714838 0.9290502241214373 2.332892865951102 0.050984574707767086 0.04685943739527981 1.7977736739326362e-07 6.745264983542182 0.1054750336324245 ITSPLMEPSS(ph)IEK ddPTM_PC-9_AZD4547_30min_R2 1 ITSPLMEPSSIEK 13 0 P28066 P28066 PSMA5 Proteasome subunit alpha type-5 1 ITSPLMEPS(0.147)S(0.853)IEK 120.87 0.00018132 3620300.0 21339.0 19759.0 20162.0 24842.0 28703.0 24285.0 24515.0 27745.0 25168.0 22755.0 True False 28124.358121226905 26145.71034169535 19894.638706383223 19115.060705074025 24718.08389984445 22766.455110954896 26696.787508152192 23457.64776667361 26498.329098509665 21958.354376082963 1.2808044555406188 1.190695345101692 0.906016833759294 0.8705142643063519 1.1256801614772818 1.0368015162261939 1.2157918144007336 1.0682789504583128 1.206753868922511 1.0 14.422482318117318 -7.201576551308134 24.99377197896347 1.128397251556274 1.0602020004914547 0.03830366339767999 0.1281253659768922 853.9170464704146 356525.0507268992 0.0522413757926144 0.04046598110749727 6.286710310854721e-08 7.201576551308134 -0.06819525106481916 ITSVIPS(ph)PPPPPPLPPPQR ddPTM_PC-9_AZD4547_30min_R2 2 ITSVIPSPPPPPPLPPPQR 19 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 ITSVIPS(1)PPPPPPLPPPQR;ITS(0.005)VIPS(0.995)PPPPPPLPPPQR 127.61 3.3046e-05 13011900.0 83362.0 80098.0 109916.0 161127.0 118660.0 107508.0 85050.0 126141.0 87265.0 101298.0 True False 109869.38196268432 105988.1120982396 108458.44202216147 123981.65953733446 102186.10722069276 100785.50776481531 92619.28523631828 106648.8068818154 91877.64974497154 97751.58785271177 1.1239651894783658 1.0842597488844712 1.109531255753946 1.2683339704327372 1.0453651901252259 1.0310370396916204 0.9474964782758655 1.0910186650114533 0.9399095376681671 1.0 16.57683251694261 -6.504483037763578 22.310883041758604 1.0079611750558555 1.141610081896383 0.5609377699722354 0.060390251965725415 147.90764639091404 179387.16059354108 0.01883891622562694 0.020915696876344085 3.1298027098582084e-07 6.504483037763578 0.13364890684052755 ITSVIPS(ph)PPPPPPLPPPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ITSVIPSPPPPPPLPPPQR 19 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 IT(0.145)S(0.016)VIPS(0.839)PPPPPPLPPPQR;IT(0.01)S(0.155)VIPS(0.835)PPPPPPLPPPQR 179.9 5.304999999999999e-09 9918500.0 28879.0 23649.0 29619.0 29587.0 44624.0 29933.0 31442.0 26269.0 31123.0 25393.0 True False 33767.64431375038 25996.716429203847 30325.229290683023 27929.336312348212 35880.247536064315 28363.26078596506 28463.586139632887 25579.46658430619 31578.114996068718 29996.549889122605 1.1257176054768636 0.8666568830514344 1.010957240175131 0.9310849552893411 1.19614581239142 0.9455507680318325 0.9488953311245436 0.8527469551950657 1.0527249004566228 1.0 14.872508955467662 ITSVIPS(ph)PPPPPPLPPPQR ddPTM_PC-9_Lapatinib_30min_R1 1 ITSVIPSPPPPPPLPPPQR 19 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 IT(0.164)S(0.084)VIPS(0.752)PPPPPPLPPPQR 63.373999999999995 0.013143 3795200.0 23833.0 20688.0 21545.0 18352.0 20010.0 18698.0 16590.0 17065.0 22863.0 14123.0 True False 23493.137049563087 20640.09820706694 19773.653266105062 19701.667300477326 18833.051141173626 17898.33012716687 17448.949024506568 17857.902198845353 20287.928181936724 16564.141732285403 1.4183129696223429 1.24607109385191 1.193762622035765 1.1894167303625836 1.1369771791113004 1.0805467869355998 1.0534170321965173 1.0781060973438945 1.224810105457697 1.0 14.015775831947908 -1.522878745280667 0.4572620838021102 1.085024611103343 8.853504997844615 0.7597270134944244 0.056061052144750795 43.86407839486449 0.5197022477152983 0.03435241147512968 319.6013669823573 0.02999999999997725 1.522878745280667 7.768480386741272 ITVGNDHFCVS(ph)TPER ddPTM_PC-9_AZD4547_30min_R2 1 ITVGNDHFCVSTPER 15 0 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 IT(0.006)VGNDHFCVS(0.945)T(0.048)PER 72.48899999999999 0.011072 5119300.0 15873.0 17059.0 23522.0 31904.0 29998.0 22058.0 20230.0 28636.0 20255.0 23518.0 True False 20920.283821089775 22572.988143073082 23210.082910998237 24549.025711886392 25833.29550317156 20678.70977300567 22030.43080929711 24210.964189816732 21325.63794859795 22694.64197832208 0.9218159881558311 0.9946395349455082 1.0227120098730134 1.0817101999377483 1.138299318748783 0.9111714471088802 0.9707326879331507 1.0668141058556042 0.9396772140740619 1.0 14.470064108619553 -10.119587892326741 15.099307011141082 1.0000152480198368 1.0096704948394961 0.0 0.0701656509558267 0.0 0.0 0.07011700048339337 0.017005870537912672 7.592977407736498e-11 10.119587892326741 0.009655246819659347 ITVGNDHFCVS(ph)TPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 ITVGNDHFCVSTPER 15 0 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 ITVGNDHFCVS(0.573)T(0.427)PER;ITVGNDHFCVS(0.5)T(0.5)PER 87.66799999999999 0.0028849 9629300.0 35670.0 33719.0 49198.0 41643.0 39434.0 32580.0 36747.0 34813.0 29504.0 23745.7 True False 41708.22648538649 37066.3994788923 50371.06690445401 39309.87771842759 31707.190779337587 30871.447446187878 33266.058134758925 33899.19563742249 29935.440183915827 28050.607439142244 1.4868920958619312 1.3214116506856561 1.795721073553846 1.4013913175931438 1.130356654419287 1.1005625283932137 1.185930044721205 1.2085013029029466 1.0671940081462714 1.0 14.775744392449448 -6.1620769756405105 3.9065166149827744 1.1280479575767062 1.5235998710185423 0.7094167340919495 0.12250028967918286 0.13373410052386506 3.6799093908157716 0.03695322953706747 0.04859221965504091 6.885302483876241e-07 6.1620769756405105 0.39555191344183616 ITVGNDHFCVS(ph)TPER ddPTM_PC-9_Lapatinib_30min_R1 2 ITVGNDHFCVSTPER 15 0 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 ITVGNDHFCVS(0.622)T(0.378)PER;ITVGNDHFCVS(0.61)T(0.39)PER 94.845 0.0016739 6362200.0 38458.0 42296.0 53136.0 43194.0 44900.0 31955.0 34712.0 27438.0 34866.0 32541.0 True False 37909.58186766654 42198.06621065851 48767.36319089154 46370.63085096003 42259.07027679641 30588.359140743276 36509.21751287957 28712.869647343625 30939.0239247433 38165.668491843055 0.993290131306589 1.105655105181173 1.2777809250560968 1.2149828021712912 1.107253506795727 0.8014626849070065 0.9565984025848386 0.7523219370173032 0.8106506487985592 1.0 15.21998784066584 -6.690171196146171 5.370248406408685 0.854708275897054 1.154052511084776 0.6666475522941961 0.09739368252463906 0.12160461656386551 6.371560942491944 0.03372899617898683 0.033342634644608654 2.0409332630572608e-07 6.690171196146171 0.2993442351877219 ITVGNDHFCVST(ph)PER ddPTM_PC-9_AZD4547_30min_R2 1 ITVGNDHFCVSTPER 15 0 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 ITVGNDHFCVS(0.231)T(0.769)PER 75.564 0.031125999999999997 4215000.0 18424.0 16660.0 20352.0 23496.0 21780.0 26132.0 16154.0 24994.0 17209.0 22589.0 True False 24282.44875699349 22045.019195943343 20082.119182239425 18079.360209581326 18756.222950165895 24497.961908975623 17591.674705555382 21131.751604982517 18118.63260713018 21798.165985556487 1.113967513279929 1.0113244944804265 0.9212756337182624 0.829398226509549 0.8604495884008687 1.1238542694467062 0.8070254496278111 0.969427961002979 0.8311998642058065 1.0 14.411919136806311 -4.968441853804504 2.3875754664622115 0.9149408710715461 1.1240915358906265 0.31759965341571816 0.09108964039501312 0.450814072273397 4.2089965209800955 0.0237014065908524 0.16709245408526752 1.075370568424137e-05 4.968441853804504 0.2091506648190804 ITVGNDHFCVST(ph)PER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ITVGNDHFCVSTPER 15 0 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 ITVGNDHFCVS(0.298)T(0.702)PER 96.391 0.0055645 4716700.0 29197.0 30645.0 38947.0 29394.0 35589.0 25334.0 21245.0 19197.0 18851.0 14491.0 True False 34139.475432964115 33687.233074250566 39875.64418732001 27747.149476633782 28615.590927774152 24005.440442041876 19232.519799519774 18693.099090902815 19126.660212411778 17118.10358930712 1.9943491552586146 1.9679302031618389 2.32944286026102 1.6209242648797926 1.6716566048618244 1.402342281480114 1.1235193021926466 1.0920075926272301 1.1173352300753285 1.0 14.063235262722754 -6.608123898066882 0.9190750751543669 1.0464992175768644 2.0879665835906835 0.8953995788803003 0.14095172332394798 0.1670314663769987 0.3082497743750937 0.07996021336736014 0.08693312919386836 2.465335911469449e-07 6.608123898066882 1.0414673660138192 ITVGNDHFCVST(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 1 ITVGNDHFCVSTPER 15 0 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 ITVGNDHFCVS(0.242)T(0.758)PER 129.42 3.1879000000000004e-05 5045500.0 24418.0 28617.0 32835.0 34461.0 27362.0 22557.0 21147.0 17872.0 24878.0 17720.0 True False 24069.794842287214 28550.73909472324 30135.433046765345 36995.376898526025 25752.620955761784 21592.28969293525 22241.88818693433 18702.39836494369 22075.977663046036 20782.878389584188 1.1581550154453264 1.3737625058246068 1.450012480555552 1.7800891774965637 1.2391267693058483 1.0389460635903407 1.070202489279895 0.899894519630968 1.0622194505122022 1.0 14.343107858180375 -6.596838014208733 3.8846423516468933 1.0127569168773483 1.4440319014830636 0.6421037040677335 0.149416630618158 0.14897831235511946 4.447563561339599 0.05355878773106564 0.054116104338083074 2.530241565319351e-07 6.596838014208733 0.43127498460571534 ITVNGDS(ph)SAEAEELANEI ddPTM_PC-9_AZD4547_30min_R2 4 ITVNGDSSAEAEELANEI 18 0 A0A0B4J1W3;Q9BXJ9 A0A0B4J1W3 NAA15 N-alpha-acetyltransferase 15, NatA auxiliary subunit 1 ITVNGDS(0.889)S(0.111)AEAEELANEI;IT(0.006)VNGDS(0.761)S(0.233)AEAEELANEI;IT(0.001)VNGDS(0.762)S(0.237)AEAEELANEI;ITVNGDS(0.958)S(0.042)AEAEELANEI 135.79 7.6327e-05 7081700.0 17834.7 16465.3 25653.94 23764.35 19413.760000000002 24021.799999999996 18112.8 28058.620000000003 20620.589999999997 22296.07 True False 23505.76361519496 21787.386228509356 25313.75199361338 18285.8462630475 16718.494529890402 22519.713048562335 19724.804110856974 23722.805001944234 21710.552289631174 21515.491375695532 1.0925041499051094 1.0126371667774674 1.1765360851673814 0.8498921053554778 0.7770445135534323 1.046674354553724 0.9167721883005021 1.1025918296591701 1.0090660682821304 1.0 14.393088168810063 -5.757247390474152 24.999873619671348 0.9562169216750195 1.0857669169048785 0.29508647450883785 0.09639201475819643 153.30828260457784 914272.8987581613 0.028184613341711955 0.046672369566548924 1.7488501939725693e-06 5.757247390474152 0.129549995229859 ITVNGDS(ph)SAEAEELANEI ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ITVNGDSSAEAEELANEI 18 0 A0A0B4J1W3;Q9BXJ9 A0A0B4J1W3 NAA15 N-alpha-acetyltransferase 15, NatA auxiliary subunit 1 IT(0.001)VNGDS(0.671)S(0.328)AEAEELANEI;ITVNGDS(0.785)S(0.215)AEAEELANEI;IT(0.001)VNGDS(0.831)S(0.168)AEAEELANEI 140.96 4.1666000000000004e-05 9033800.0 11769.099999999999 15710.5 18817.5 16195.599999999999 20887.6 16054.5 15518.6 13121.599999999999 14116.3 11883.400000000001 True False 13761.376179679335 17270.13461292261 19266.180565766168 15288.213038843644 16794.82472289121 15212.573757667999 14048.565863065549 12777.171903484408 14322.724182084148 14037.766351057355 0.9803109579924586 1.2302622925207605 1.3724534291251398 1.0890773258732933 1.1964029250013972 1.083689055454478 1.0007693184042332 0.9101997842072649 1.0202993712746422 1.0 13.77702577597437 -7.055452980316883 2.079800093168403 0.971265679976181 1.1850780189951093 0.45368609739145305 0.0980758127331151 0.29087726612769765 2.50052760471932 0.04504123872713819 0.0337546778608496 8.801303954495481e-08 7.055452980316883 0.21381233901892838 ITVNGDS(ph)SAEAEELANEI ddPTM_PC-9_Lapatinib_30min_R1 3 ITVNGDSSAEAEELANEI 18 0 A0A0B4J1W3;Q9BXJ9 A0A0B4J1W3 NAA15 N-alpha-acetyltransferase 15, NatA auxiliary subunit 1 ITVNGDS(0.5)S(0.5)AEAEELANEI;ITVNGDS(0.886)S(0.113)AEAEELANEI;IT(0.003)VNGDS(0.801)S(0.196)AEAEELANEI 182.09 3.2939e-09 2522400.0 8954.699999999999 16615.83 17086.11 12670.39 16413.2 15821.84 14585.24 12100.16 14572.0 12169.849999999999 True False 8827.004335909136 16577.35706650855 15681.355990091915 13602.212747781994 15447.807845592755 15145.176785710446 15340.392361072587 12662.377607405842 12930.74791003726 14273.392357194192 0.6184237156109618 1.1614167572541432 1.0986425369430883 0.9529768682443662 1.0822800536136474 1.0610775915563513 1.0747544786254402 0.887131614582405 0.9059337532692289 1.0 13.801040640450031 -11.648312618090143 10.43004212252535 1.0919984655005344 0.9954762355854425 0.0 0.1483355099427109 1.145997661982712 0.01378204656987801 0.5186831753755675 0.033790454356040535 2.2474362519512797e-12 11.648312618090143 -0.09652222991509185 ITVNGDSS(ph)AEAEELANEI ddPTM_PC-9_AZD4547_30min_R2 1 ITVNGDSSAEAEELANEI 18 0 A0A0B4J1W3;Q9BXJ9 A0A0B4J1W3 NAA15 N-alpha-acetyltransferase 15, NatA auxiliary subunit 1 ITVNGDS(0.152)S(0.848)AEAEELANEI 81.788 0.002966 1647600.0 8033.7 5015.9 6118.5 7053.6 6235.8 8457.9 7301.6 9484.5 7911.6 7647.8 True False 10588.249488659292 6637.191583729427 6037.364692243121 5427.501497033661 5370.066807743089 7929.026175949985 7951.428254926532 8018.888457127973 8329.79102414848 7380.05284980915 1.4347118786463848 0.8993420126931837 0.8180652381641479 0.7354285406200062 0.727646118127997 1.0743860968631183 1.0774215871817445 1.0865624705296444 1.1286898879543785 1.0 12.849415432368431 -6.939904702150752 24.95057808286846 1.079742982364229 0.9050218865632562 0.1328753567370241 0.1889962726438353 138.27692815150453 57409.306967165154 0.0696458071594485 0.06142182225686403 1.1484055901054856e-07 6.939904702150752 -0.17472109580097284 ITVNGDSS(ph)AEAEELANEI ddPTM_PC-9_Lapatinib_30min_R1 2 ITVNGDSSAEAEELANEI 18 0 A0A0B4J1W3;Q9BXJ9 A0A0B4J1W3 NAA15 N-alpha-acetyltransferase 15, NatA auxiliary subunit 1 ITVNGDS(0.003)S(0.997)AEAEELANEI;ITVNGDS(0.028)S(0.972)AEAEELANEI 204.78 4.1931e-20 4942600.0 7109.8 11800.0 11735.400000000001 7499.0 11288.0 10108.8 11725.0 11322.2 13328.4 10406.8 True False 7008.412948222364 11772.677824989838 10770.560711954018 8050.501475930664 10624.062033061873 9676.47018876375 12332.063129134389 11848.270745723219 11827.215237725812 12205.601513810645 0.574196440895792 0.964530737110256 0.8824276869736508 0.6595743328849067 0.870425109409048 0.7927892925076095 1.010360949042999 0.9707240345604348 0.9689989652982944 1.0 13.575255775005092 -7.258077488151965 24.792138213835823 0.9850813281026829 0.8003994784965172 0.45442982153042033 0.10533524612161842 258.71397957975137 1907885.173040768 0.04056139186520727 0.0301050303453038 5.519789447198091e-08 7.258077488151965 -0.18468184960616574 ITVQAS(ph)PGLDR ddPTM_PC-9_Lapatinib_30min_R1 1 ITVQASPGLDR 11 0 Q16584;Q16584-2 Q16584 MAP3K11 Mitogen-activated protein kinase kinase kinase 11 1 IT(0.001)VQAS(0.999)PGLDR 65.895 0.043552999999999994 9466900.0 38226.0 34981.0 36712.0 24880.0 37131.0 29873.0 24201.0 28581.0 38236.0 26109.0 True False 37680.890230210134 34900.00364372622 33693.68107241817 26709.758197246956 34947.02758235472 28595.401427364206 25454.00936359755 29908.977600070273 33929.45903707003 30621.905861944313 1.2305207389798178 1.1397071038317883 1.1003129989466574 0.8722434951522982 1.1412427345283396 0.9338217404326042 0.8312353084211777 0.9767183576003334 1.1080126491811932 1.0 14.902276456378303 -5.379916726669209 2.1714564266815364 0.9780018497092796 1.2030264335784775 0.4437752814463545 0.0922263531752597 0.3083692153810458 2.7495217105631298 0.026667956515106714 0.08055129864368023 4.169493233080145e-06 5.379916726669209 0.22502458386919788 ITVQAS(ph)PNLDK ddPTM_PC-9_AZD4547_30min_R2 2 ITVQASPNLDK 11 0 Q5TCX8;Q5TCX8-2 Q5TCX8 MLK4 Mitogen-activated protein kinase kinase kinase MLK4 1 IT(0.031)VQAS(0.969)PNLDK;IT(0.003)VQAS(0.997)PNLDK 123.95 0.00053626 20909000.0 105684.0 145411.0 192200.0 238465.0 244590.0 237870.0 228764.0 265750.0 214943.0 217860.0 True False 139289.31363624075 192412.26208291203 189651.30241875115 183490.57849752365 210632.9004307194 222995.95129680212 249123.55282541015 224684.4438274831 226304.44816516835 210232.78771142327 0.6625480028711634 0.9152343180028957 0.9021014489855723 0.8727971525992063 1.0019031889537866 1.0607096719989189 1.1849890568324215 1.0687412095581255 1.0764469739886906 1.0 17.681628162670492 -4.608532250009488 0.46968916379637166 1.0962146000940551 0.3888946069268217 0.7536682815490897 0.06820086875058895 2.903498897032905 0.43978946047667716 0.048550366071503204 1.182606195434151 2.4630189316209634e-05 4.608532250009488 -0.7073199931672334 ITVQAS(ph)PNLDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 ITVQASPNLDK 11 0 Q5TCX8;Q5TCX8-2 Q5TCX8 MLK4 Mitogen-activated protein kinase kinase kinase MLK4 1 ITVQAS(1)PNLDK;ITVQAS(1)PNLDK;IT(0.045)VQAS(0.955)PNLDK 118.08 0.0010989 18691600.0 196391.0 192820.0 233689.0 277097.0 327311.0 271773.0 316863.0 259939.0 248005.0 229302.0 True False 229636.11740094033 211961.89529701372 239261.03203046782 261572.15345059443 263176.7591716728 257520.74545097674 286847.44275054045 253115.8766781362 251631.6039456361 270872.6374463669 0.8477641727337947 0.7825149756552373 0.8832971624084466 0.9656647342328405 0.9715885725954218 0.9507078598958382 1.0589753378369071 0.9344460889972818 0.9289664925843958 1.0 18.04725513961123 -5.600661426186816 2.811530660407221 0.9736388222064342 0.8155623800065719 0.7401731549539299 0.03801670523664522 0.1283796910531519 2.0373062092102403 0.010895319527671154 0.02210853103611398 2.5080637650780447e-06 5.600661426186816 -0.15807644219986228 ITVQAS(ph)PNLDK ddPTM_PC-9_Lapatinib_30min_R1 2 ITVQASPNLDK 11 0 Q5TCX8;Q5TCX8-2 Q5TCX8 MLK4 Mitogen-activated protein kinase kinase kinase MLK4 1 ITVQAS(1)PNLDK;ITVQAS(1)PNLDK 130.2 0.00022117 24014000.0 219414.0 257770.0 232281.0 221883.0 218700.0 211351.0 183493.0 190352.0 202798.0 153199.0 True False 216285.11612440067 257173.14940234204 213183.7528105891 238201.01599998935 205836.49598074332 202312.01041324463 192993.36970185573 199196.44883414023 179956.7536823863 179679.24302516377 1.2037290033223833 1.43129025407974 1.186468449117036 1.3257013553125316 1.1455774886135082 1.1259620588723829 1.074099414337066 1.1086224846029828 1.001544478107489 1.0 17.45506422933748 -6.689689708531324 0.7025931008243197 1.0213007254387478 1.3179696178154319 0.6965546277907997 0.0709219796951501 0.38411996616932886 0.41982662594571113 0.04788602314197091 0.0526441368663644 2.0431972315522484e-07 6.689689708531324 0.29666889237668403 ITVTSEVPFS(ph)KR ddPTM_PC-9_AZD4547_30min_R2 1 ITVTSEVPFSKR 12 1 K7ERI7;P35268;K7EP65;K7EKS7;K7ELC4;K7EMH1 K7ERI7 RPL22 60S ribosomal protein L22 1 ITVTSEVPFS(1)KR 74.85300000000001 0.039283 0.0 22480.0 31474.0 30487.0 40709.0 37810.0 36058.0 21374.0 25186.0 29718.0 30740.0 True False 29628.172386952552 41647.354992384186 30082.722460148074 31324.16899778033 32560.734148107105 33803.287559844015 23276.24459307544 21294.082416703593 31288.83280950055 29663.80195652779 0.998798887289382 1.4039789995031067 1.0141222795457645 1.0559728332762537 1.09765882997145 1.1395466976681758 0.7846682845033386 0.7178473766751142 1.0547816107778172 1.0 14.856415896839898 -7.252435682864803 24.704500605689958 0.8658115985467721 1.122816763240821 0.38929358693368044 0.13921993585100592 516.3951675447279 1416896.8645852718 0.05296316542602524 0.040410648136248804 5.5919633599842746e-08 7.252435682864803 0.2570051646940489 ITVTSEVPFS(ph)KR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 ITVTSEVPFSKR 12 1 K7ERI7;P35268;K7EP65;K7EKS7;K7ELC4;K7EMH1 K7ERI7 RPL22 60S ribosomal protein L22 1 ITVTSEVPFS(1)KR 60.937 0.026543999999999998 3582100.0 18665.0 19095.0 17919.0 23141.0 20645.0 17555.0 18773.0 22211.0 18726.0 14274.0 True False 21824.615849446003 20990.625405541356 18346.25691818592 21844.484794134263 16599.760451372542 16634.384896188712 16994.68553524993 21627.984784499793 18999.83232388855 16861.76320707818 1.2943258413381427 1.2448653884980412 1.088039055754536 1.2955041845780666 0.9844617225086131 0.9865151521761366 1.0078830622005148 1.2826644828828377 1.126799854235461 1.0 14.04146778398509 -5.141785061108294 0.9131447815685573 1.0851952626684007 1.3457812326927805 0.31374350320446986 0.10680839007140737 1.8899514905124595 1.7983134994185768 0.04173370117378746 0.438282124086386 7.2146445448332315e-06 5.141785061108294 0.2605859700243798 ITVTSEVPFSK ddPTM_PC-9_Lapatinib_30min_R1 2 ITVTSEVPFSK 11 0 K7ERI7;P35268;K7EP65;K7EKS7;K7ELC4;K7EMH1;K7EJT5 K7ERI7 RPL22 60S ribosomal protein L22 0 ; 156.16 0.00096944 14653100.0 89147.0 102120.0 111686.0 102799.0 100548.0 101516.0 109572.0 87691.0 93983.0 94839.0 False True 87875.74743244221 101883.54741423421 102503.60820042736 110359.1813874112 94633.96432497389 97174.39732535425 115245.10202008646 91765.44399173453 83397.64485513525 111231.7947849757 0.790023640293825 0.9159570571632619 0.9215315494870782 0.9921550002923951 0.8507815998825929 0.8736206901381384 1.0360805760877 0.8249929273291693 0.7497644447466916 1.0 16.76320970514356 -10.651975477886568 7.16912501852184 1.0000000624407452 0.8905835840189086 0.14494483475630537 0.08318901443895294 8.439557584440342e-08 1.0385819484336647e-08 0.08191373528995 0.019866987738059175 2.2285609797484328e-11 10.651975477886568 -0.10941647842183666 IVADKDYSVTANSK ddPTM_PC-9_AZD4547_30min_R2 1 IVADKDYSVTANSK 14 1 A0A5F9ZHM4;P07195;A0A3B3IS95;A8MW50;C9J7H8;F5H793 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain;L-lactate dehydrogenase 0 76.156 0.021564 17827000.0 66511.0 52417.0 62241.0 93284.0 79533.0 84696.0 70744.0 76424.0 62364.0 80835.0 False True 87660.11448525816 69359.77017969755 61415.64367245308 71778.81502343308 68491.21578951085 79399.94573100419 77040.07895071238 64614.42684881113 65660.43372137056 78004.99125425906 1.1237757107045625 0.8891709243786436 0.7873296655116258 0.92018233537734 0.878036324191899 1.0178828874193222 0.9876301209956998 0.8283370821515628 0.8417465685926284 1.0 16.25127881926003 -4.7593908823851265 24.95813778785782 0.9021983060052964 1.1237759992947767 0.443510550742518 0.07323136712276573 52.139557867290804 635086.0207510954 0.01912656949875398 0.12186176224676777 1.740239882897773e-05 4.7593908823851265 0.2215776932894803 IVADKDYSVTANSK ddPTM_PC-9_Lapatinib_30min_R1 2 IVADKDYSVTANSK 14 1 A0A5F9ZHM4;P07195;A0A3B3IS95;A8MW50;C9J7H8;F5H793 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain;L-lactate dehydrogenase 0 ; 117.48 0.00016786 64172000.0 345800.0 253092.0 257968.0 228762.0 251810.0 194677.0 231722.0 214690.0 229559.0 223845.0 False True 340868.8285880458 252505.9810239262 236758.8668252774 245585.92060766154 236999.03087750805 186351.1185242519 243719.4313355461 224665.281164378 203703.64805656366 262536.3099952865 1.298368323201334 0.9617945076948008 0.9018137979829459 0.9354360187818237 0.9027285821216998 0.709810839222954 0.9283265668658243 0.8557493672719463 0.7759065710195321 1.0 18.002157442463094 -1.8822361963515968 1.0066744788382944 0.8606551022474062 199.99987178094855 0.7222894766206985 0.07831099041685864 382.501470571227 1.1560162887399446 0.024216836645943717 174851.79466226662 0.013114864371276989 1.8822361963515968 199.13921667870116 IVAEEFLK ddPTM_PC-9_Lapatinib_30min_R1 2 IVAEEFLK 8 0 H7C0A3;F8WCF6;P59998;P59998-3;R4GN08;P59998-4 H7C0A3 ARPC4-TTLL3;ARPC4 Actin-related protein 2/3 complex subunit 4 0 ; 121.62 0.015501 5443000.0 61626.0 52885.0 55762.0 54551.0 60767.0 53087.0 52020.0 57876.0 56861.0 53972.0 False True 60747.20193917569 52762.548031744715 51177.46360754472 58562.86251680136 57192.80453251869 50816.59276184125 54713.341064185166 60565.130246725654 50456.71540712521 63300.98828683054 0.9596564537652542 0.8335185509690013 0.8084781137325772 0.9251492607262354 0.9035057126338322 0.802777241511305 0.8643362851819488 0.9567801686174611 0.7970920640053021 1.0 15.949940403458662 -11.543324301591033 2.99564166068333 1.1473734032231704 0.8720125554918241 0.29720857113313814 0.05887807496178118 10761516.3537862 109755.48187574263 10940228.568920279 0.013860789178878593 2.8620399948830957e-12 11.543324301591033 -0.2753608477313463 IVAHAVEVPAVQS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 IVAHAVEVPAVQSPR 15 0 Q96FF9;B5MBX0;H0YCL8 Q96FF9 CDCA5 Sororin 1 IVAHAVEVPAVQS(1)PR;IVAHAVEVPAVQS(1)PR;IVAHAVEVPAVQS(1)PR;IVAHAVEVPAVQS(1)PR 131.37 5.4941e-06 153165000.0 139282.0 122261.0 158263.0 195859.0 178233.0 129421.0 117238.0 141640.0 122594.0 120202.0 True False 183570.77875442719 161779.4773058362 156164.32921279268 150706.7335413852 153488.4244755246 121328.28441074272 127671.95487989971 119752.79256340412 129074.06855938864 115993.7645666412 1.5825917836209322 1.3947256381431608 1.346316586897846 1.2992658191966913 1.3232472025454594 1.045989712154197 1.1006794663220807 1.0324071557708885 1.1127673029806056 1.0 16.823687727457134 -5.178824607432828 0.35617921821415127 0.9952785689628374 1.847627340604209 0.890304123104429 0.06056259661401494 1.518755947048831 0.19096409734294875 0.06079721850609026 0.5441793891220319 6.624839980267599e-06 5.178824607432828 0.8523487716413716 IVAHAVEVPAVQS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 IVAHAVEVPAVQSPR 15 0 Q96FF9;B5MBX0;H0YCL8 Q96FF9 CDCA5 Sororin 1 IVAHAVEVPAVQS(1)PR;IVAHAVEVPAVQS(1)PR;IVAHAVEVPAVQS(1)PR;IVAHAVEVPAVQS(1)PR;IVAHAVEVPAVQS(1)PR 117.48 8.4487e-05 86537800.0 82726.0 82521.0 95675.0 94719.0 118177.0 117648.0 128270.0 112813.0 117904.0 102043.0 True False 96729.87788702235 90713.13951771006 97956.2548494579 89412.20151314147 95021.06519069293 111478.33177253272 116119.33700562046 109851.77828525381 119628.12294754639 120542.58812805646 0.802453965765717 0.7525401679723553 0.8126277722309699 0.7417478162834521 0.7882779577434396 0.9248045317734968 0.9633054906890083 0.9113109316066331 0.9924137585337175 1.0 16.879183420278657 -6.802401655876651 3.55639361865306 0.9577427671134726 0.7759424008396637 0.9001904275145796 0.029982755302979624 0.0664035657520093 1.737970500185011 0.01036226882575323 0.009419284554797614 1.576152895401518e-07 6.802401655876651 -0.1818003662738089 IVAHAVEVPAVQS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 5 IVAHAVEVPAVQSPR 15 0 Q96FF9;B5MBX0;H0YCL8 Q96FF9 CDCA5 Sororin 1 IVAHAVEVPAVQS(1)PR;IVAHAVEVPAVQS(1)PR;IVAHAVEVPAVQS(1)PR;IVAHAVEVPAVQS(1)PR;IVAHAVEVPAVQS(1)PR 159.44 1.6544e-05 131568000.0 160139.0 148940.0 155286.0 137796.2 193055.0 216834.0 224263.0 211378.0 229916.0 186887.0 True False 157855.38849410423 148595.1385808465 142518.9845012946 147930.192222648 181699.88446073362 207560.51528474197 235874.24081271354 221199.39355332783 204020.4389571868 219190.16893872575 0.7201754953628073 0.6779279349083673 0.6502070106124858 0.6748942844421167 0.8289600092033668 0.9469426310938479 1.076116880400105 1.0091665818057916 0.930791923492793 1.0 17.741823566798146 -6.587102488425452 2.08772098285904 1.0049110758731337 0.6771313166220566 0.9365143453463252 0.03840690048084249 0.07452497492757404 0.6600409780440932 0.015132282752068073 0.015648048523945236 2.5876021991975107e-07 6.587102488425452 -0.32777975925107705 IVDQIRPDR ddPTM_PC-9_AZD4547_30min_R2 2 IVDQIRPDR 9 1 P17844-2;P17844;J3KTA4;J3QSF1;J3KRZ1;A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 P17844-2;A0A1X7SBZ2 DDX5;DDX17 Probable ATP-dependent RNA helicase DDX5;Probable ATP-dependent RNA helicase DDX17 0 ; 120.87 0.0021401999999999997 15086400.0 38194.0 39997.0 49930.0 72709.0 53837.0 44420.0 44590.0 61113.0 43566.0 48892.0 False True 50338.897515447745 52925.248066035194 49267.89557631755 55947.06339285186 46362.66184426452 41642.41037795413 48558.4236177241 51669.39008703275 45868.809818248235 47180.30596156662 1.066947246091497 1.1217656814084342 1.044247055465293 1.185813916476648 0.9826698004466491 0.8826227284722635 1.029209595573206 1.0951474144555773 0.9722024663344333 1.0 15.525897153951403 -6.289967596928159 24.99250885053627 0.9946267754638022 1.1015953261460856 0.44735830046581404 0.0604225950774132 726.9866687631463 636883.9547289814 0.019621114389078043 0.0222524985086299 5.128996504325234e-07 6.289967596928159 0.10696855068228339 IVDQIRPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IVDQIRPDR 9 1 P17844-2;P17844;J3KTA4;J3QSF1;J3KRZ1;A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 P17844-2;A0A1X7SBZ2 DDX5;DDX17 Probable ATP-dependent RNA helicase DDX5;Probable ATP-dependent RNA helicase DDX17 0 74.301 0.035813 7140300.0 17991.0 18057.0 25262.0 20813.0 25400.0 18981.0 21442.0 23712.0 18409.0 14233.0 False True 21036.520961552793 19849.57962544436 25864.341886668517 19646.915086656423 20423.05233542564 17985.602945859195 19410.85853336329 23089.585124940742 18678.196798593613 16813.33023163399 1.25118109688781 1.1805858418279156 1.5383235522255552 1.1685320407072652 1.2146940584679662 1.069722815056567 1.1544921955343561 1.3732904074826346 1.1109159542617506 1.0 14.037317888348113 -5.905922438486656 22.462339466867473 1.1702079015361484 1.3164828559013535 0.26609067058440605 0.12570021656930197 11.786340852391557 2803.85028611485 0.03511638505111945 0.0520860242672334 1.2418740765444672e-06 5.905922438486656 0.1462749543652051 IVDQIRPDR ddPTM_PC-9_Lapatinib_30min_R1 2 IVDQIRPDR 9 1 P17844-2;P17844;J3KTA4;J3QSF1;J3KRZ1;A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 P17844-2;A0A1X7SBZ2 DDX5;DDX17 Probable ATP-dependent RNA helicase DDX5;Probable ATP-dependent RNA helicase DDX17 0 ; 101.72 0.0044168 17599500.0 42205.0 41450.0 49171.0 44539.0 48828.0 43303.0 39127.0 41807.0 50372.0 38507.0 False True 41603.14896055088 41354.02507168042 45128.35018554897 47814.54663774849 45956.03303954155 41451.0316342233 41152.80461011866 43749.505843957086 44698.574919324514 45162.88364264775 0.9211800842863945 0.915663964216612 0.9992353575699012 1.058713323446795 1.0175619741903466 0.9178118908926508 0.9112085254728436 0.9687048814271019 0.9897192409812205 1.0 15.462849984440926 -5.455891820645386 0.0035534140060372713 1.927681893497764 3.415079823520368e-05 0.04460166398038845 0.04767811840128702 235415.9646340025 164.9798506614967 43842.8338199316 45664.442952937636 3.5003234648655946e-06 5.455891820645386 -1.9276477426995289 IVDS(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 1 IVDSPEK 7 0 E9PQC4;Q9BZD4 E9PQC4 NUF2 Kinetochore protein Nuf2 1 IVDS(1)PEK 85.86200000000001 0.019 5705800.0 44095.0 46402.0 39736.0 32207.0 28601.0 41746.0 42638.0 52839.0 44429.0 34476.0 True False 58116.29276702281 61400.53905943353 39209.07467695881 24782.173743189713 24630.244839196286 39135.616020668014 46432.699399249126 44673.94666942749 46777.426236398824 33269.00573367771 1.7468599221825427 1.84557781951622 1.1785466325874614 0.7449027464654014 0.7403360664386631 1.1763386117984171 1.395674393486488 1.3428097920042357 1.4060361950957478 1.0 15.021891130515446 -9.510386329160804 15.585326436314125 0.9999502598868821 1.2692774994559621 0.057254346489152286 0.34233182641293025 0.0 0.0 0.37782195746773306 0.09163528460688747 3.0875476647184653e-10 9.510386329160804 0.26932723956908 IVDS(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 4 IVDSPEK 7 0 E9PQC4;Q9BZD4 E9PQC4 NUF2 Kinetochore protein Nuf2 1 IVDS(1)PEK;IVDS(1)PEK;IVDS(1)PEK;IVDS(1)PEK 89.04700000000001 0.016862000000000002 38150300.0 222183.0 377068.0 313107.0 297695.0 364370.0 327753.0 350845.0 338797.0 285985.0 279380.0 True False 219014.6296766275 376194.9222129885 287364.55108797166 319588.4833814087 342938.47297898284 313735.76821955974 369010.0374022308 354538.7454592558 253774.35774444157 327670.4607495504 0.6683990652548562 1.1480892154649454 0.876992544371017 0.9753350443929121 1.0465956320704244 0.9574734551960685 1.1261620487794828 1.0819978848512737 0.7744804251317909 1.0 18.321886095285187 -4.744887836022711 24.9813906755768 1.0008104705057772 0.6683980953332973 0.45988213903818465 0.10731993524075639 878.0573403115527 1325188.0482197031 0.025690726044579087 0.6951786931494977 1.799335564306264e-05 4.744887836022711 -0.3324123751724799 IVEGQGQSS(ph)EVITPPEEISR ddPTM_PC-9_Lapatinib_30min_R1 1 IVEGQGQSSEVITPPEEISR 20 0 A0A087WWA3;Q4R9M9;O60333-2;O60333;O60333-4 A0A087WWA3 KIF1B;KIF1Bbeta Kinesin-like protein;Kinesin-like protein KIF1B 1 IVEGQGQS(0.133)S(0.783)EVIT(0.084)PPEEISR 112.91 3.3771e-05 2421200.0 6386.7 5342.9 6590.6 6984.4 7655.4 7139.6 5459.4 3922.3 6125.1 5575.7 True False 6295.624486822662 5330.528843316798 6048.746308451704 7498.056075275383 7205.124423095482 6834.255951220487 5742.061018950644 4104.544377060133 5435.226737837584 6539.452315846751 0.962714334894188 0.815133834740193 0.9249622164526008 1.1465877741941313 1.101793250427966 1.045080783701007 0.8780645139098536 0.62765873636142 0.8311440278670816 1.0 12.674954098627278 -7.499369613299106 6.96117559461158 0.788191796362314 0.9964083256318536 0.30553076005285706 0.12151658025215012 0.2016586191451645 41.2576228270641 0.05658216409729698 0.036214317447371455 3.1668710992651944e-08 7.499369613299106 0.2082165292695396 IVEGQGQSSEVIT(ph)PPEEISR ddPTM_PC-9_AZD4547_30min_R2 1 IVEGQGQSSEVITPPEEISR 20 0 A0A087WWA3;Q4R9M9;O60333-2;O60333;O60333-4 A0A087WWA3 KIF1B;KIF1Bbeta Kinesin-like protein;Kinesin-like protein KIF1B 1 IVEGQGQSSEVIT(1)PPEEISR 127.67 5.8243000000000005e-05 3255900.0 10760.0 8288.5 15509.0 19499.0 15665.0 13249.0 16325.0 15564.0 13109.0 14998.0 True False 14181.45617809651 10967.595534548407 15303.340526599419 15003.806806546922 13490.185147582586 12420.537935558637 17777.89337428449 13158.941425139947 13801.91497744608 14472.924585035911 0.9798611258404013 0.7578009178523744 1.0573772036663622 1.0366810604444046 0.932098075155493 0.8581912980048751 1.2283552829858386 0.9092109440510359 0.9536369029184597 1.0 13.82106886036849 -5.2758042587312515 24.970077781511854 0.9961138903385652 0.8688310046243792 0.1839396420696645 0.10792706795375444 1136.1180594635066 1974882.964313796 0.027818291725307472 0.058325793213978475 5.299022227998087e-06 5.2758042587312515 -0.127282885714186 IVEGQGQSSEVIT(ph)PPEEISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IVEGQGQSSEVITPPEEISR 20 0 A0A087WWA3;Q4R9M9;O60333-2;O60333;O60333-4 A0A087WWA3 KIF1B;KIF1Bbeta Kinesin-like protein;Kinesin-like protein KIF1B 1 IVEGQGQS(0.003)S(0.004)EVIT(0.993)PPEEISR 153.17 3.1366e-15 0.0 3569.3 2710.7 2839.6 2482.7 3429.8 2588.2 3749.1 3098.5 4095.3 2875.9 True False 4173.511993111578 2979.800381607801 2907.3068332429693 2343.6023680219996 2757.7553110253098 2452.4702357342994 3393.9581068665384 3017.167658132121 4155.18601495358 3397.277904388128 1.228487074231054 0.8771141088454707 0.8557753928484089 0.6898471170094335 0.8117544070984678 0.7218927343466786 0.9990228066072248 0.8881132904184748 1.2230927618804728 1.0 11.730163523156987 -8.183450116338461 7.310662683586618 1.1103019460347108 0.8716191021882095 0.2637257407830391 0.15100088180375248 0.3234670143801547 26.224146664598837 0.10558327350440623 0.03932072912985054 6.554655691866523e-09 8.183450116338461 -0.2386828438465013 IVENIQVFDFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IVENIQVFDFK 11 0 O60218 O60218 AKR1B10 Aldo-keto reductase family 1 member B10 0 ; 174.77 0.0021971 9947400.0 62512.0 64507.0 61848.0 84040.0 72338.0 62952.0 72950.0 63015.0 58806.0 55880.0 False True 73094.04693172086 70910.82864808885 63322.6908798462 79331.51126135602 58163.88818267797 59650.68629933764 66039.64788773679 61360.92301991146 59665.926499978064 66010.6016541633 1.107307691492777 1.074233939263247 0.9592806199767826 1.2017995484571162 0.8811294962497825 0.9036531224462103 1.0004400237665712 0.9295616383166448 0.9038839974914079 1.0 16.01041012713562 -6.281175441174393 24.999897908019765 0.934482978966901 1.0758128688086166 0.5473592456712658 0.06621725272059217 648.1414705876396 821006.1830552663 0.020090928603835795 0.022809935804802946 5.23388961360173e-07 6.281175441174393 0.14132988984171557 IVENIQVFDFK ddPTM_PC-9_Lapatinib_30min_R1 2 IVENIQVFDFK 11 0 O60218 O60218 AKR1B10 Aldo-keto reductase family 1 member B10 0 ; 194.17 0.000346 63472000.0 147055.0 123218.0 150102.0 120767.0 144675.0 123607.0 145074.0 119033.0 117239.0 131731.0 False True 144957.968733416 122932.69629149161 137761.1929704757 129648.60804690214 136165.5009419938 118320.61675199034 152585.22186746614 124563.70773133096 104034.30923859843 154500.52782947608 0.9382360744644684 0.7956781638129662 0.8916551607029086 0.8391466998093153 0.8813270922432134 0.7658266182920883 0.9876032400088375 0.8062348360959212 0.673358924400713 1.0 17.237252241341004 -4.738690765594448 24.01346823625251 0.8466964404375918 0.9382366803121127 0.07530752097542659 0.09352010919077787 3158.8000937773886 3334148.5466634147 0.022188364510296172 1.1046072745547597 1.825194848805175e-05 4.738690765594448 0.09154023987452087 IVEPEVVGES(ph)DSEVEGDAWR ddPTM_PC-9_AZD4547_30min_R2 2 IVEPEVVGESDSEVEGDAWR 20 0 P55081 P55081 MFAP1 Microfibrillar-associated protein 1 1 IVEPEVVGES(0.966)DS(0.034)EVEGDAWR;IVEPEVVGES(0.894)DS(0.106)EVEGDAWR 127.91 2.4877e-05 2969400.0 11427.2 10418.8 14336.8 18498.0 17410.4 15684.1 10764.0 17478.3 12160.699999999999 14861.300000000001 True False 15060.811899474384 13786.473349261367 14146.684664501294 14233.571891251075 14993.266485379629 14703.370747610767 11721.975147368958 14777.43034637777 12803.489775438897 14341.01041042767 1.0501918252931 0.9613320787520601 0.9864496475237841 0.9925083019883679 1.0454818772377215 1.0252674202732337 0.8173744256433735 1.0304316030363363 0.8927885420213622 1.0 13.80785905371198 IVEPEVVGES(ph)DSEVEGDAWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IVEPEVVGESDSEVEGDAWR 20 0 P55081 P55081 MFAP1 Microfibrillar-associated protein 1 1 IVEPEVVGES(0.915)DS(0.085)EVEGDAWR 99.09200000000001 0.00037372 1903400.0 8275.9 9028.9 11102.0 12865.0 13047.0 12288.0 12039.0 10508.0 11760.0 7737.4 True False 9676.84641352425 9925.229522078678 11366.713784569467 12144.21575889275 10490.534008673167 11643.5956482123 10898.57876518797 10232.176134146313 11931.967752265795 9140.129370775296 1.0587209459490865 1.0858959561134514 1.2436053499322959 1.3286700074205446 1.1477445868781313 1.2738983416844845 1.1923878014281888 1.1194782610914387 1.305448453543463 1.0 13.157998870214039 -11.83627943801963 2.259225475166881 3.2386698525214746e-05 1.1958596875548069 0.3076510276976514 0.08779422679080602 2316637.7144342335 467105.418130069 11809431.541502994 0.022509855554017546 1.4578759175919594e-12 11.83627943801963 1.1958273008562816 IVEPEVVGES(ph)DSEVEGDAWR ddPTM_PC-9_Lapatinib_30min_R1 2 IVEPEVVGESDSEVEGDAWR 20 0 P55081 P55081 MFAP1 Microfibrillar-associated protein 1 1 IVEPEVVGES(0.778)DS(0.222)EVEGDAWR;IVEPEVVGES(0.889)DS(0.111)EVEGDAWR 187.73 9.018100000000002e-21 1394300.0 5806.6 4426.57 5167.7 4908.2 5771.4 6413.2 5605.3 5938.9 6880.6 5303.9 True False 5723.796819199972 4416.320549132652 4742.8316538988665 5269.1654012752215 5431.937599008972 6138.922385899382 5895.515007056459 6214.842975020376 6105.634372069887 6220.672047997486 0.9201251528832058 0.7099426742090225 0.7624307498135423 0.8470411815024766 0.8732075179493802 0.986858387410984 0.9477295960256096 0.9990629512483323 0.9815071948754105 1.0 12.602854734461419 -6.489810386756341 1.6044215479306283 0.9847958365290468 0.7920379654810878 0.7059836847731612 0.05289926711404441 0.1989898188454154 1.0377030568861876 0.020343681121124384 0.022938703963911917 3.2373496896977027e-07 6.489810386756341 -0.19275787104795894 IVEPEVVGESDS(ph)EVEGDAWR ddPTM_PC-9_Lapatinib_30min_R1 1 IVEPEVVGESDSEVEGDAWR 20 0 P55081 P55081 MFAP1 Microfibrillar-associated protein 1 1 IVEPEVVGES(0.153)DS(0.847)EVEGDAWR 191.07 4.106e-12 1446400.0 4314.9 3775.2 3063.5 3046.1 4343.3 3125.4 2565.8 2817.1 4255.9 3690.6 True False 4253.368734744248 3766.4587563475948 2811.630855451979 3270.120355491718 4087.8356332563462 2991.7339276632456 2698.6445694441813 2947.9927503291665 3776.5557253861903 4328.515292584615 0.9826391839323974 0.8701502713413289 0.649560106734223 0.7554831470952444 0.9443967173361756 0.6911686168207669 0.6234573259028003 0.6810632632809482 0.8724829347041899 1.0 12.079656541175398 -6.797928768045305 24.997086743515844 0.7443148483844209 0.8267716290584577 0.03192012886524864 0.13406412467375012 493.79783569850537 338273.41721194435 0.04814942100824786 0.042464980179271555 1.5924698987820308e-07 6.797928768045305 0.08245678067403683 IVEVLLMK ddPTM_PC-9_Lapatinib_30min_R1 2 IVEVLLMK 8 0 P38159;P38159-2;H0Y6E7;H3BT71;H3BR27;P38159-3;O75526 P38159;O75526 RBMX;RBMXL2 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA-binding motif protein, X-linked-like-2 0 ; 143.11 0.0085139 3198300.0 30197.6 23941.3 31816.5 29233.2 33748.2 29399.4 26698.7 27946.5 24123.4 27327.3 False True 29766.97668643839 23885.86539079909 29200.670185241648 31383.107047096433 31763.19722751403 28142.056195348683 28081.028048257594 29244.996413714136 21406.36866133633 32050.787393661605 0.9287440062182415 0.7452505018807364 0.9110749706890634 0.9791680516810887 0.9910270483337813 0.8780457044532417 0.8761415968773025 0.9124579703616784 0.6678890099770115 1.0 14.968072179606477 -9.939223323207393 9.507623390737056 0.9999927181946725 0.8812518360498034 0.13070319445042722 0.09476992310012212 0.0 0.0 0.09288072930399605 0.022526885735575135 1.1502087756993e-10 9.939223323207393 -0.11874088214486911 IVEYS(ph)PPSAPR ddPTM_PC-9_AZD4547_30min_R2 3 IVEYSPPSAPR 11 0 O95696-2;O95696 O95696-2 BRD1 Bromodomain-containing protein 1 1 IVEYS(0.886)PPS(0.113)APR;IVEYS(0.967)PPS(0.033)APR;IVEY(0.001)S(0.863)PPS(0.136)APR 103.46 0.0028951999999999997 42137400.0 99035.0 101951.0 99630.0 152503.0 142130.0 121214.0 106135.0 128610.0 111047.0 111369.0 True False 130526.06994403242 134904.66698953297 98308.84110291436 117345.78949786277 122397.70284238194 113634.46941813007 115580.80938926115 108736.27966379155 116916.71771305642 107470.00520808522 1.2145348806051108 1.2552773839391587 0.9147560839191097 1.0918934010532138 1.138901059931964 1.057359857739926 1.0754703990706211 1.0117825848547652 1.0879009216262745 1.0 16.71357453540724 -5.234110834506007 24.99124294117075 1.0539142872267566 1.2349061967920039 0.6141468732208337 0.05930735144982295 486.1903137899997 444606.8204127391 0.014941228832881228 0.03951087030117915 5.832962246499923e-06 5.234110834506007 0.18099190956524724 IVEYS(ph)PPSAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IVEYSPPSAPR 11 0 O95696-2;O95696 O95696-2 BRD1 Bromodomain-containing protein 1 1 IVEYS(0.967)PPS(0.033)APR;IVEYS(0.872)PPS(0.128)APR 98.156 0.005092800000000001 36454000.0 69046.0 70258.0 74523.0 85914.0 90705.0 72061.0 80850.0 59083.0 59574.0 62777.0 True False 80734.12407933816 77232.74992105401 76299.91095005127 81100.51711694617 72932.00638129057 68281.99430385954 73191.30269668977 57532.133853613064 60445.15704706486 74157.9731575414 1.0886775978602645 1.0414625242923043 1.0288834457214673 1.0936183078339534 0.9834681730898122 0.9207640311150506 0.9869647130349958 0.7758051009753414 0.8150864225840557 1.0 16.178314193152545 -6.875835713742794 1.1393042185007327 0.8637465428279864 1.0618460595401342 0.5660893494464221 0.06695729539320185 0.3343632197406706 0.9100024967582135 0.037057835548591676 0.02993868479102119 1.3309578015869553e-07 6.875835713742794 0.19809951671214787 IVEYS(ph)PPSAPR ddPTM_PC-9_Lapatinib_30min_R1 3 IVEYSPPSAPR 11 0 O95696-2;O95696 O95696-2 BRD1 Bromodomain-containing protein 1 1 IVEYS(0.985)PPS(0.015)APR;IVEYS(0.993)PPS(0.007)APR;IVEYS(0.612)PPS(0.388)APR 137.4 9.098299999999999e-05 40509000.0 127714.0 124843.0 128057.0 117534.0 130693.0 134051.0 114840.0 107179.0 136208.0 91326.0 True False 125892.77494012071 124553.93370383114 117528.64777431492 126177.84244193009 123005.89469232404 128317.95121814348 120785.85328356437 112158.92761617615 120866.82070617308 107111.5774157544 1.1753423670670722 1.1628428663726433 1.097254382858415 1.178003774066083 1.148390282918491 1.1979839557406236 1.1276638454752017 1.0471223589662062 1.1284197621049648 1.0 16.70875490016072 -8.472196604988957 0.659095394746359 1.0034262726235823 1.1592458960358185 0.6132512113681032 0.03684997214121596 0.5287846081199483 0.5343065037138132 0.03741024366320908 0.015542642588953109 3.3713465334588086e-09 8.472196604988957 0.1558196234122362 IVGCSVHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IVGCSVHK 8 0 B4DY08;B2R5W2;G3V4W0;G3V576;G3V555;G3V575;G3V5X6;G3V3K6;G3V251;B4DSU6;G3V4M8;G3V2H6;B3KT61;E5RG71;Q86SE5;Q86SE5-3;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4 B4DY08;P07910-2 HNRNPC;RALYL RNA-binding Raly-like protein;Heterogeneous nuclear ribonucleoproteins C1/C2 0 76.47800000000001 0.019887000000000002 0.0 20607.0 20050.0 31059.0 39758.0 56161.0 42626.0 49446.0 24618.0 39975.0 24483.0 False True 24095.35809319764 22040.431494166223 31799.56435191343 37530.48815717512 45156.65520511181 40390.61752121564 44762.11692196066 23971.803584927093 40559.55874973 28921.574092678635 0.8331274783310384 0.7620757924011355 1.0995101528710827 1.2976640910660457 1.5613484612009072 1.3965566808979577 1.5477068011070665 0.8288554249540465 1.402398037525816 1.0 14.819858454449164 -5.470712890165342 2.7597783473765207 1.3091930387318338 0.7948350418925216 0.44758938861669073 0.21637178852892008 0.2420308611274844 3.606882523959941 0.06134301403826313 0.1439310480283888 3.3828840301111173e-06 5.470712890165342 -0.5143579968393122 IVHFT(ph)GSDQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IVHFTGSDQR 10 0 Q5JU07;H0Y577;H7C3U8;A0A3B3ITA5;A4D256;O60729-2;O60729-5;O60729-3;O60729-4;O60729 Q5JU07 CDC14B;CDC14C Dual specificity protein phosphatase CDC14C;Dual specificity protein phosphatase CDC14B 1 IVHFT(1)GSDQR 84.31 0.030869999999999998 4303500.0 640.29 0.0 2221.1 690.96 367.35 598.19 0.0 0.0 454.83 0.0 True False 748.6784506960505 0.0 2274.0594475686567 652.2477513225447 295.3704045440396 566.8198633466891 0.0 0.0 461.48102829617795 0.0 0.0 IVILPDYLEIAR ddPTM_PC-9_Lapatinib_30min_R1 1 IVILPDYLEIAR 12 0 P45974-2;P45974 P45974-2 USP5 Ubiquitin carboxyl-terminal hydrolase 5 0 128.35 0.00095566 6796700.0 7227.0 7406.1 9458.8 7938.5 10017.0 9629.0 8979.4 10635.0 7960.5 6596.8 False True 7123.941654730512 7388.951630479425 8681.133976023884 8522.323772059679 9427.81975417973 9217.190116295316 9444.309395458362 11129.140924976282 7063.9046622187525 7737.048090316527 0.9207570602600542 0.9550091383983034 1.1220214576265783 1.1014955151598425 1.2185292949102031 1.1913057807965926 1.2206605523466496 1.4384220952310227 0.9129973834671827 1.0 12.917567525738695 -5.285145028617827 1.2578076002553127 1.1868660073143644 0.8839306915458498 0.2762462505697192 0.13435794601841622 0.7871819712949122 1.884385183310193 0.04108943900996113 0.24491129076348117 5.186268193875789e-06 5.285145028617827 -0.3029353157685146 IVLDNSVFSEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IVLDNSVFSEHR 12 0 A0A087WVQ6;Q00610-2;Q00610;A0A087WX41;P53675-2;P53675 A0A087WVQ6 CLTC;CLTCL1 Clathrin heavy chain;Clathrin heavy chain 1;Clathrin heavy chain 2 0 120.84 0.00039815 2247200.0 9437.3 12830.0 17310.0 20907.0 20938.0 20552.0 19656.0 17455.0 18508.0 15670.0 False True 11034.848494828646 14103.677609483926 17722.736048540577 19735.648571408532 16835.349204690632 19474.216940271748 17794.04138288353 16996.82474510125 18778.644486304027 18510.846956348243 0.5961287736239576 0.7619142248187142 0.9574243734138062 1.0661666977177533 0.9094856245309184 1.052043538915064 0.9612764572493596 0.9182089174624307 1.0144670598048429 1.0 14.17608328619874 -5.049154754938173 2.2017467360369722 0.9860232456316779 0.5836722665665592 0.8740564383366134 0.04854128072368414 0.12336983806143094 0.9979182284438041 0.013044531648937614 0.07814253490840385 8.929872231681611e-06 5.049154754938173 -0.40235097906511863 IVLDNSVFSEHR ddPTM_PC-9_Lapatinib_30min_R1 1 IVLDNSVFSEHR 12 0 A0A087WVQ6;Q00610-2;Q00610;A0A087WX41;P53675-2;P53675 A0A087WVQ6 CLTC;CLTCL1 Clathrin heavy chain;Clathrin heavy chain 1;Clathrin heavy chain 2 0 92.792 0.0047576 3289900.0 22021.0 21213.0 26769.0 26136.0 30681.0 35468.0 30269.0 26735.0 31756.0 22830.0 False True 21706.97650184318 21163.882601822836 24568.156151328214 28058.128627140126 28876.403901166846 33951.116319946224 31836.180712645528 27977.20570091595 28179.30487449516 26776.135080937165 0.8106837090651334 0.7904009498700998 0.917539296730659 1.047878214773261 1.0784380872699186 1.2679617957304514 1.1889759525194052 1.0448560113828327 1.0524037464449811 1.0 14.708660113850057 -5.677048701848628 1.7374844579447182 1.119296281356338 0.793989963560438 0.7370125165084653 0.0731245229328051 0.19007008838242193 1.154270218075643 0.024388233575908903 0.05678970958232287 2.1035425349627476e-06 5.677048701848628 -0.3253063177959 IVLLDSSLEYK ddPTM_PC-9_Lapatinib_30min_R1 2 IVLLDSSLEYK 11 0 P49368-2;P49368;B4DUR8;Q5SZX6 P49368-2 CCT3 T-complex protein 1 subunit gamma 0 ; 119.16 0.0045747 6765500.0 77411.0 62373.0 71831.0 64907.0 59995.0 54614.0 67236.0 62546.0 63744.0 64894.0 False True 76307.1049445614 62228.5791506857 65925.33245567848 69680.47730340455 56466.212054708245 52278.28653145214 70717.15109172542 65452.11549539888 56564.479465922 76110.84143418023 1.00257865379863 0.8176046668003303 0.8661753202753637 0.9155131646214083 0.7418944658960257 0.6868704319431522 0.9291337444072378 0.8599578491324539 0.7431855751435662 1.0 16.215814349300743 -4.758099332198334 24.97525492171104 0.8337672006620167 1.0025788914297171 0.21880015281914855 0.09145068810266582 142.7795652274094 1067461.5725377274 0.02253344998192538 0.15858539641099118 1.7454228926740106e-05 4.758099332198334 0.16881169076770042 IVLNFT(ph)T(ph)MDLYK ddPTM_PC-9_Lapatinib_30min_R1 1 IVLNFTTMDLYK 12 0 E9PD25;O43897 E9PD25 TLL1 Metalloendopeptidase;Tolloid-like protein 1 2 IVLNFT(0.969)T(0.733)MDLY(0.298)K 63.76 0.040088 0.0 25162.0 27392.0 34317.0 28349.0 33575.0 31124.0 24604.0 24784.0 29661.0 20377.0 True False 24803.18526585433 27328.575506959456 31495.588727450784 30433.88002949171 31600.184510989737 29792.89907358764 25877.87473170341 25935.555118440276 26320.265835823164 23899.13729935423 1.0378276401853437 1.143496318074121 1.3178546293510691 1.2734300677168815 1.3222311799448758 1.2466098127480385 1.0827953497887408 1.0852088422095918 1.1013061059963178 1.0 14.544670920918364 -7.270325339689805 15.122188057815556 1.074423549188626 1.2309714617638383 0.45577942822018436 0.08326385655098663 3.3380159714283963 5675.201980894741 0.03721431276176179 0.025912849182164813 5.36629644514366e-08 7.270325339689805 0.15654791257521228 IVLTNPVCTEVGEK ddPTM_PC-9_Lapatinib_30min_R1 1 IVLTNPVCTEVGEK 14 0 Q2VIR3;P41091 Q2VIR3 EIF2S3L;EIF2S3 Putative eukaryotic translation initiation factor 2 subunit 3-like protein;Eukaryotic translation initiation factor 2 subunit 3 0 179.93 1.4911000000000002e-26 0.0 13582.0 13324.0 13972.0 13340.0 15282.0 11785.0 13646.0 10766.0 14095.0 13631.0 False True 13388.318189366244 13293.149096624114 12823.276093479682 14321.068100935458 14383.14280556799 11280.983022176788 14352.523109609203 11266.227663215297 12507.472673069946 15987.100187834196 0.8374450670894298 0.8314921993633271 0.8021014407126748 0.8957889756538494 0.8996717751548977 0.705630345067916 0.8977564999893559 0.7047073910119503 0.7823478007967847 1.0 13.964620659579499 IVNHWAS(ph)PELR ddPTM_PC-9_AZD4547_30min_R2 3 IVNHWASPELR 11 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0 O15027 SEC16A Protein transport protein Sec16A 1 IVNHWAS(1)PELR;IVNHWAS(1)PELR;IVNHWAS(1)PELR 134.02 3.2597e-05 22707300.0 93131.3 89786.2 112497.0 146709.0 118778.7 104827.1 82781.6 120798.0 84343.3 102968.1 True False 122745.11614862103 118807.83328516262 111005.21627576611 112887.506681455 102288.32777460395 98272.24486561985 90149.00203079147 102131.44476189015 88801.51464774043 99363.21816005063 1.235317438600949 1.1956922841789537 1.117166073435373 1.136109606470474 1.0294385555210346 0.9890203506424935 0.9072673339301749 1.0278596713461974 0.8937061046543622 1.0 16.600424279641253 -6.054966803764946 0.8406501166674302 0.9518499606288336 1.2286277708155575 0.8507355252147146 0.04220343346076044 0.24359730927267056 0.35173618297688103 0.019940934292246845 0.043685875190762044 8.811162204520368e-07 6.054966803764946 0.27677781018672387 IVNHWAS(ph)PELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IVNHWASPELR 11 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0 O15027 SEC16A Protein transport protein Sec16A 1 IVNHWAS(1)PELR;IVNHWAS(1)PELR;IVNHWAS(1)PELR;IVNHWAS(1)PELR 104.59 0.0026634000000000002 25673800.0 109309.0 105412.0 117468.0 121134.0 128414.0 116993.0 111021.0 105118.0 92999.0 75257.0 True False 127812.8547488395 115876.60671636158 120268.88261987096 114347.25470172666 103252.19852761218 110857.68112559414 100504.2871575658 102358.76388172754 94358.93443817757 88900.49836591573 1.4377068418982304 1.3034415874634562 1.3528482385424039 1.2862386241196502 1.161435542269118 1.246986048034313 1.130525576402156 1.1513857150768425 1.0613993866467974 1.0 16.439903886208768 -4.552315818484861 0.18014623268179852 0.9478576596368004 1.8573267495815076 0.9029778577632656 0.04017511946137398 5.344065972954431 0.16075764126689826 0.11010957531674864 1.1289874561606887 2.8033942711995825e-05 4.552315818484861 0.9094690899447072 IVNHWAS(ph)PELR ddPTM_PC-9_Lapatinib_30min_R1 2 IVNHWASPELR 11 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0 O15027 SEC16A Protein transport protein Sec16A 1 IVNHWAS(1)PELR;IVNHWAS(1)PELR 97.631 0.0030096999999999997 15791500.0 113678.0 102686.0 121781.0 96433.0 102536.0 88143.0 82031.0 82678.0 102245.0 78095.0 True False 112056.93087400807 102448.23687600903 111768.63626825438 103525.00451105791 96505.03407353231 84373.32936136858 86278.16379923443 86519.52171087824 90729.09141241823 91593.61669495371 1.2234141954150148 1.1185084787863098 1.2202666550496875 1.130264403204438 1.0536218303829592 0.9211704090948629 0.9419669941255618 0.9446020894559235 0.990561293311359 1.0 16.482959437659574 -6.383899120181599 2.188915322310821 0.9554427139132259 1.1788381877097054 0.8785100166433645 0.03744728227353937 0.09559567978264388 0.9004097291524558 0.012455068063575233 0.01471596443029567 4.131434576113667e-07 6.383899120181599 0.2233954737964795 IVNQPS(ph)SLFGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IVNQPSSLFGSK 12 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 IVNQPS(0.652)S(0.14)LFGS(0.207)K 88.163 0.02913 0.0 14589.0 11929.0 13677.0 13615.0 12898.0 17244.0 13904.0 16006.0 15193.0 9008.5 True False 17058.62955411561 13113.232283985486 14003.111550311338 12852.195690425557 10370.729489067711 16339.694283672921 12586.912463757257 15585.859459758827 15415.168882667873 10641.669738753239 1.603003097530273 1.2322532653152805 1.3158754118554257 1.207723600331474 0.9745396863145586 1.5354445951436992 1.1827948783187778 1.4646065741920724 1.448566743857049 1.0 13.377436915240247 -4.756997439427813 24.911386207268343 1.2739499595684263 1.6030036106353887 0.24611955961082155 0.17779399995007913 193.22899388103096 1083528.6208367022 0.04326671654138777 0.3331616917316723 1.7498570056380136e-05 4.756997439427813 0.3290536510669624 IVPQSQVPNPES(ph)PGK ddPTM_PC-9_AZD4547_30min_R2 4 IVPQSQVPNPESPGK 15 0 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 IVPQSQVPNPES(1)PGK;IVPQSQVPNPES(1)PGK;IVPQSQVPNPES(1)PGK;IVPQSQVPNPES(1)PGK 179.9 7.698e-06 53014600.0 204534.0 204095.0 202874.0 168210.0 178554.0 214511.0 209568.0 198382.0 199477.0 198095.0 True False 269571.5574285127 270064.7174547453 200183.75820448346 129431.7833185937 153764.8591663874 201097.5932594629 228219.14601298954 167726.62026484893 210020.94697963304 191159.75434542508 1.410189913413457 1.4127697452819448 1.047206609413988 0.6770869933464702 0.8043788280274455 1.0519870877008985 1.1938660770645178 0.8774159646688363 1.0986671734267133 1.0 17.54441929316404 -5.3135925665719785 4.236562091734889 0.9543875100735257 1.4171288328023905 0.6173061053615388 0.1404633267438379 0.1389185485022243 5.28519104620592 0.04050931204875499 0.09456698388162202 4.85743987259631e-06 5.3135925665719785 0.4627413227288648 IVPQSQVPNPES(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IVPQSQVPNPESPGK 15 0 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 IVPQSQVPNPES(1)PGK;IVPQSQVPNPES(1)PGK;IVPQSQVPNPES(1)PGK;IVPQSQVPNPES(1)PGK 191.36 9.7301e-08 34040500.0 114340.0 144539.0 114048.0 141020.0 121379.0 99550.0 131802.0 108762.0 94564.0 82222.0 True False 133695.5036820603 158887.87669502728 116767.33684944833 133119.10659300836 97595.656276442 94329.42275224077 119316.76039615434 105907.11274286457 95946.81960248828 97128.197731006 1.376484963226915 1.6358573556060731 1.2021981214233215 1.3705505682467025 1.004812799540774 0.9711847327125707 1.2284461483224365 1.090384823531592 0.9878369190810117 1.0 16.567602571393827 -5.827598437329845 1.3254617619113649 1.057799184989838 1.4925460874369623 0.6553298450199432 0.12269319472236959 0.2750414473118683 0.9725242610937858 0.04189286375647101 0.09497617375168789 1.4873102216482884e-06 5.827598437329845 0.4347469024471242 IVPQSQVPNPES(ph)PGK ddPTM_PC-9_Lapatinib_30min_R1 3 IVPQSQVPNPESPGK 15 0 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 IVPQSQVPNPES(1)PGK;IVPQSQVPNPES(1)PGK;IVPQSQVPNPES(1)PGK 229.69 1.1238e-24 50072000.0 181820.0 238940.0 166836.0 159349.0 191945.0 170461.0 173380.0 162503.0 162030.0 150609.0 True False 179227.21345829577 238386.74911042964 153119.38808558384 171068.0570326811 180655.17247838955 163170.78039399895 182356.76804514445 170053.48262636748 143780.47514845862 176641.56497612238 1.0146378259416062 1.3495507081963054 0.866836681990911 0.9684473586712466 1.0227217614541046 0.9237394404655306 1.0323548031845995 0.962703668580804 0.8139673987144205 1.0 17.430465333443664 -5.274335550506568 24.999410585544013 0.9529385831548585 1.1820942828439491 0.47157821957669266 0.09868624802598892 546.4494704298073 1059300.385350676 0.024289808008249404 0.05108668235779411 5.3169729333333024e-06 5.274335550506568 0.22915569968909066 IVPQSQVPNPES(ph)PGKSFQPITMSCK ddPTM_PC-9_AZD4547_30min_R2 1 IVPQSQVPNPESPGKSFQPITMSCK 25 1 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 IVPQS(0.006)QVPNPES(0.753)PGKS(0.198)FQPIT(0.032)MS(0.012)CK 48.5 0.043256 0.0 10335.0 7291.7 12544.0 20982.0 17095.0 11421.0 10965.0 10458.0 11849.0 10736.0 True False 13621.315018645664 9648.599428034815 12377.658363895996 16144.92406866851 14721.65433117934 10706.843064534312 11940.863757980373 8841.95640093251 12475.313949787062 10360.135907784072 1.3147814989966793 0.9313197735934482 1.1947389951319136 1.5583699106242463 1.4209904640457707 1.0334655027536601 1.1525779067250097 0.8534594989520475 1.204165086329973 1.0 13.338755308461948 -6.784860826162002 24.82358826013182 1.046064972026526 1.2747239248329099 0.312500988037796 0.17421132290824964 308.49723990954226 326963.1465144522 0.06639314879294221 0.05858816743489754 1.6411156001984045e-07 6.784860826162002 0.22865895280638382 IVRGDQPAASGDS(ph)DDDEPPPLPR ddPTM_PC-9_AZD4547_30min_R2 2 IVRGDQPAASGDSDDDEPPPLPR 23 1 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 IVRGDQPAASGDS(1)DDDEPPPLPR;IVRGDQPAAS(0.009)GDS(0.991)DDDEPPPLPR 117.94 1.1188e-08 6860500.0 7940.4 5566.6 13775.900000000001 15342.8 14216.0 5405.7 9438.8 13568.4 11161.7 13003.8 True False 10465.282029419837 7365.894589203972 13593.22256498684 11805.754503897015 12242.353786021968 5067.680724450846 10278.83491462153 11471.715550813988 11751.684674937822 12548.540920048677 0.8339839743997297 0.586992116145994 1.0832512442358206 0.9408069495183364 0.9755997820003505 0.40384621261857334 0.8191259031716698 0.914187205022836 0.9364980956600519 1.0 13.615232004300395 -7.852727611719514 3.7430106319251975 0.9549653550801755 0.804635874836278 0.11826652427439288 0.18351805183894201 0.5816173046935968 15.43527501503102 0.11654359698672395 0.05227739505781918 1.40369382135592e-08 7.852727611719514 -0.15032948024389758 IVRGDQPAASGDS(ph)DDDEPPPLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IVRGDQPAASGDSDDDEPPPLPR 23 1 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 IVRGDQPAAS(0.053)GDS(0.947)DDDEPPPLPR;IVRGDQPAAS(0.004)GDS(0.996)DDDEPPPLPR 88.186 0.00028339 0.0 6970.0 5855.4 7602.5 8036.9 10516.4 7942.2 6976.1 9448.4 7216.1 6251.5 True False 8149.883336224942 6436.685415009522 7783.772432641806 7586.618548981355 8455.786912609063 7525.69705055597 6315.273305409738 9200.389511407306 7321.621810980031 7384.847463153227 1.1035953520893789 0.871607091023265 1.054019391934501 1.0273223092060964 1.1450184929071723 1.0190727822213679 0.8551663845353421 1.2458469260621488 0.99143846200092 1.0 12.850352406542452 IVRGDQPAASGDS(ph)DDDEPPPLPR ddPTM_PC-9_Lapatinib_30min_R1 3 IVRGDQPAASGDSDDDEPPPLPR 23 1 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 IVRGDQPAAS(0.001)GDS(0.999)DDDEPPPLPR;IVRGDQPAAS(0.003)GDS(0.997)DDDEPPPLPR;IVRGDQPAAS(0.217)GDS(0.783)DDDEPPPLPR 129.8 3.4879e-07 14700800.0 82757.0 49532.0 29552.9 28125.5 28854.2 27986.2 27662.0 21010.3 46423.0 13049.9 True False 81576.87000422501 49417.31169723703 27123.174639492994 30193.94309391758 27157.052685539853 26789.295465018593 29094.203008794506 21986.515239871107 41194.35288413804 15305.557827101278 5.3298854524451444 3.228716800490256 1.7721127805917973 1.972743720614593 1.7743262279178968 1.7502985364952375 1.9008913845190223 1.4365053197172584 2.6914636728362775 1.0 13.901768005905833 -4.814144142816882 1.846544662626374 1.79548317188684 6.334878262810777 0.879568186957272 0.40697790680947094 0.22593843480832482 0.8528770042486635 0.10259459579887183 1.763604848630345 1.5341077262485348e-05 4.814144142816882 4.539395090923938 IVT(ph)ENIPCGTT(ph)GT(ph)T(ph)CSKAIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IVTENIPCGTTGTTCSKAIK 20 1 Q9HC84 Q9HC84 MUC5B Mucin-5B 4 IVT(0.962)ENIPCGT(0.273)T(0.825)GT(0.95)T(0.955)CS(0.035)KAIK 50.188 0.043878 0.0 932.28 606.66 2287.0 1047.7 2744.8 1175.2 2089.8 910.44 783.6 843.54 True False 1090.096590630673 666.8851955237343 2341.5307534957974 989.0007656892298 2206.9761437116645 1113.570443178637 1891.8390151582216 886.5419146909178 795.0586675744449 996.467124541034 1.093961420084746 0.6692495709087213 2.3498324187807906 0.9925071699126621 2.2148007589594916 1.117518496851103 1.8985463429409073 0.8896850612098749 0.7978774693050146 1.0 9.960678398206843 -7.799069233420701 21.263149047695943 0.8828278505630575 1.4751208761633938 0.2096685076627105 0.5165302915950198 55.468290354952536 31339.88237857557 0.2723329000407844 0.13084153792267664 1.5882935292637145e-08 7.799069233420701 0.5922930256003364 IVVELPHS(ph)VNSK ddPTM_PC-9_Lapatinib_30min_R1 2 IVVELPHSVNSK 12 0 Q8N4Q0;Q8N4Q0-2 Q8N4Q0 ZADH2 Zinc-binding alcohol dehydrogenase domain-containing protein 2 1 IVVELPHS(0.666)VNS(0.334)K;IVVELPHS(0.897)VNS(0.103)K 128.69 0.00019746 7482300.0 19036.4 21374.1 25449.0 26263.0 26929.0 24676.0 22498.0 27875.0 27304.0 22687.0 True False 18764.937445151783 21324.609584670798 23356.68145598085 28194.46863079972 25345.089164451016 23620.665002565514 23662.836356440555 29170.174262690547 24228.735996133484 26608.417721472706 0.7052256034754251 0.8014234370449644 0.8777929488506286 1.059607111025136 0.9525214700759077 0.8877140027572512 0.8892988904539372 1.0962761697457317 0.9105665827164595 1.0 14.699595102113438 -5.234928893789075 2.0585939838038967 0.966881484036169 0.7172708622287919 0.6254773749154132 0.06760304278560073 0.24518802928374375 1.8655188154100744 0.019285443719933834 0.07911649687698544 5.8219853222808975e-06 5.234928893789075 -0.24961062180737714 IVYLYTK ddPTM_PC-9_Lapatinib_30min_R1 1 IVYLYTK 7 0 P49207 P49207 RPL34 60S ribosomal protein L34 0 107.43 0.045654 7249900.0 68219.0 62832.0 71114.0 67938.0 73144.0 71013.0 71508.0 64610.0 60486.0 62500.0 False True 67246.18455016745 62686.51636438658 65267.28142797838 72934.3871545242 68841.81372663692 67975.93952938824 75210.33434866882 67612.01647040133 53673.429734182915 73303.0417239849 0.917372362300818 0.8551693748320327 0.8903761684779145 0.9949708148421884 0.939139933453972 0.9273276787796157 1.0260192835089386 0.9223630408815429 0.7322128587280827 1.0 16.16158544406217 -3.2774161897259333 18.25785817867039 0.9213950233944127 0.8959706573766137 0.0 0.08002716391800427 0.0 0.0 0.018367757545415975 0.0 0.0005279390787869316 3.2774161897259333 -0.02542436601779896 IWDMTPVVGCSLATGFS(ph)PH ddPTM_PC-9_AZD4547_30min_R2 2 IWDMTPVVGCSLATGFSPH 19 0 Q8IWB7 Q8IWB7 WDFY1 WD repeat and FYVE domain-containing protein 1 1 IWDMTPVVGCSLATGFS(1)PH;IWDMTPVVGCSLATGFS(1)PH 140.93 5.6101000000000004e-05 6999600.0 19550.5 14862.599999999999 24788.0 30353.0 23567.0 25181.0 21387.0 28951.0 15151.400000000001 22632.7 True False 25767.15232433788 19666.64479601605 24459.29492380851 23355.584799175278 20295.128846031213 23606.42808931254 23290.401567891106 24477.28817779662 15952.272071803845 21840.33606185774 1.1797965128081516 0.9004735430954356 1.1199138536391184 1.069378453382125 0.9292498425184448 1.0808637752849934 1.0663939191194856 1.1207377079029517 0.7304041488474672 1.0 14.414707435030907 -8.24856704286001 24.999267441537054 0.8652020559721129 1.0522232082875753 0.36946014669724603 0.10067670804069476 688.6312559150659 1337392.3558748984 0.06417542674121458 0.023910765335081248 5.641998380267619e-09 8.24856704286001 0.18702115231546246 IWDMTPVVGCSLATGFS(ph)PH ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IWDMTPVVGCSLATGFSPH 19 0 Q8IWB7 Q8IWB7 WDFY1 WD repeat and FYVE domain-containing protein 1 1 IWDMT(0.087)PVVGCS(0.271)LAT(0.015)GFS(0.627)PH 67.846 0.0078097999999999996 2440900.0 7223.8 6267.3 8991.4 8734.9 9000.6 7667.0 10392.0 9688.3 6440.6 5905.5 True False 8446.646663446454 6889.476124857253 9205.789076074387 8245.511871927889 7236.99704134772 7264.929023017884 9407.594528435367 9433.992390602367 6534.781590581895 6976.1204020877185 1.2107942777075145 0.9875798764590509 1.319614419687969 1.1819623797577066 1.0373956618039348 1.0413996038319142 1.3485424542873414 1.352326486191249 0.9367357806247516 1.0 12.768209224718994 -5.234012048491793 24.96393713062219 1.1648413724213225 1.0991871669324915 0.013948052701092672 0.15124220828804893 3416.093861940697 3109265.2911241897 0.03851298482880394 0.10185472797035923 5.834289181688466e-06 5.234012048491793 -0.06565420548883094 IWGEDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IWGEDLR 7 0 P43490;A0A0C4DFS8 P43490 NAMPT Nicotinamide phosphoribosyltransferase 0 110.34 0.043677999999999995 4545600.0 45487.0 39885.0 39746.0 46531.0 60981.0 46694.0 50796.0 48086.0 35431.0 35062.0 False True 53187.05069079826 43844.51920921793 40693.69537754441 43924.01892553741 49032.21080577133 44245.2844399109 45984.23514880708 46823.79345132846 35949.11134613345 41418.463049360704 1.2841386853831895 1.058574268122068 0.9825013383294173 1.0604936951231314 1.1838249706981374 1.068250272521733 1.1102351889302384 1.1305053351575582 0.8679489459396618 1.0 15.337986398771672 -8.25325100592625 24.767002060201552 0.9339744689723853 1.1033150372414073 0.41823347926491206 0.0826715690539314 477.10867380063735 1443101.5622244328 0.05809159263388835 0.021121795274804532 5.581475131625584e-09 8.25325100592625 0.169340568269022 IWGEDLR ddPTM_PC-9_Lapatinib_30min_R1 2 IWGEDLR 7 0 P43490;A0A0C4DFS8 P43490 NAMPT Nicotinamide phosphoribosyltransferase 0 ; 120.65 0.027485000000000002 18934400.0 166864.0 147373.0 173197.0 154248.0 151710.0 161135.0 157071.0 136587.0 161937.0 142188.0 False True 164484.4887608898 147031.76687306984 158957.4112197536 165591.91247624365 142786.71607333602 154243.63167403103 165203.36782569444 142933.33065535812 143697.94978779202 166765.006346399 0.9863249632793335 0.8816703821403641 0.9531820536112491 0.9929655873503904 0.8562150969295319 0.9249160543528001 0.9906356941727885 0.8570942656786252 0.8616792751430549 1.0 17.34745706257791 -6.250062586821952 24.937307392415416 0.9122133563932113 0.9483772358734194 0.09963242053905375 0.055359347185124544 1931.0946821048035 4232849.651764624 0.01651588027507809 0.0211320677748441 5.62260291186992e-07 6.250062586821952 0.03616387948020805 IWHHTFYNELR ddPTM_PC-9_AZD4547_30min_R2 2 IWHHTFYNELR 11 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;Q6S8J3;A5A3E0;P0CG38;P0CG39;Q9BYX7;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;A6NL76 P60709;P63261;P68133 ACTB;POTEE;POTEF;POTEI;POTEJ;POTEKP;ACTG1;ACTA1;ACTC1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;POTE ankyrin domain family member J;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1 0 ; 66.92 0.017245 33558000.0 29759.7 19309.0 127036.0 252218.0 173754.0 164178.0 60129.0 155293.0 92868.0 125900.0 False True 39222.66555978613 25550.25664192497 125351.41963615222 194073.0368292554 149631.25631235642 153911.92370625286 65480.3645146923 131296.03512813261 97776.81288622036 121492.27932097774 0.32284080749000865 0.21030354179480173 1.031764490194301 1.5974104520380443 1.231611236110211 1.2668453054504287 0.5389672897789315 1.0806944759119528 0.8047985718326836 1.0 16.89050510975551 -5.277974032516184 7.542645579875438 1.0856727580177454 0.26513466990148543 0.5915617133241299 0.2664645242225769 0.1100569876872257 37.24312983174725 0.07482175086485794 0.16583523407399303 5.272613866730297e-06 5.277974032516184 -0.8205380881162601 IWHHTFYNELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IWHHTFYNELR 11 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;Q6S8J3;A5A3E0;P0CG38;P0CG39;Q9BYX7;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;A6NL76 P60709;P63261;P68133 ACTB;POTEE;POTEF;POTEI;POTEJ;POTEKP;ACTG1;ACTA1;ACTC1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;POTE ankyrin domain family member J;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1 0 57.174 0.032579000000000004 10453000.0 11053.0 16530.0 55913.0 48651.0 56973.0 54384.0 50735.0 41118.0 43468.0 26295.0 False True 12924.054593299043 18170.98915703579 57246.17797123334 45925.24219867011 45809.54963410254 51532.007302439575 45929.013510408855 40038.696068122175 44103.63726662324 31062.075348894527 0.4160718319086493 0.5849895395892304 1.8429605017769903 1.4784988344413552 1.474774274402527 1.6590007822601447 1.4786202465394325 1.2889897284196472 1.4198548155988828 1.0 14.922866603206854 -5.17645457683792 6.195196038102219 1.474146847871871 0.4722829530625527 0.7675644752416447 0.21028012572460958 0.09842925343131667 5.800066013574512 0.051713621332105185 0.14097094973969063 6.661091864785416e-06 5.17645457683792 -1.0018638948093181 IWTHPGWS(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 1 IWTHPGWSPLK 11 0 O43172-2;O43172 O43172-2 PRPF4 U4/U6 small nuclear ribonucleoprotein Prp4 1 IWTHPGWS(1)PLK 80.312 0.017235 0.0 13771.0 12527.0 12282.0 10390.0 11473.0 10045.0 10552.0 8954.4 12697.0 9307.0 True False 13574.623014707899 12497.994501156578 11272.221369891035 11154.115260023944 10798.18069678586 9615.398766038685 11098.330928667463 9370.454113644353 11266.930154662574 10915.702549202022 1.2435867461137673 1.1449555761365289 1.0326610970830343 1.0218412612241208 0.9892336886346583 0.8808776826500834 1.0167307948015487 0.8584380227848337 1.0321763628018819 1.0 13.414117366646991 -4.847030099131857 0.8249548767108398 0.9532654289569683 1.3987914289826113 0.7445271223129992 0.053655461665483455 1.0367142058657428 0.57959080422322 0.019059501650299307 0.4161971678894741 1.4222302148866886e-05 4.847030099131857 0.445526000025643 IWYEHR ddPTM_PC-9_AZD4547_30min_R2 2 IWYEHR 6 0 O75874;H0YL11;P48735-2;P48735 O75874 IDH1;IDH2 Isocitrate dehydrogenase [NADP] cytoplasmic;Isocitrate dehydrogenase [NADP], mitochondrial 0 ; 126.04 0.010484 37385000.0 26443.0 31299.0 37574.0 53397.0 45828.0 41203.0 31292.0 41933.0 34833.0 35074.0 False True 34851.32395143179 41415.78966469572 37075.744209584525 41087.14662542621 39465.5732488615 38626.569896507084 34076.927379363595 35453.21837447914 36674.20126702111 33846.069935694715 1.0297007604619086 1.2236513646453775 1.095422431024517 1.213941432594362 1.1660311913271901 1.1412423944610113 1.006820805018352 1.047484048867059 1.0835586328545577 1.0 15.046700703351124 -7.212341876326791 7.3810399626098215 1.0385060144670033 1.1507269895830474 0.4765597100549799 0.056506853360491105 0.22563813243424302 29.885780128183185 0.020605638389358184 0.015846832809980782 6.132790422422537e-08 7.212341876326791 0.11222097511604412 IWYEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IWYEHR 6 0 O75874;H0YL11;P48735-2;P48735 O75874 IDH1;IDH2 Isocitrate dehydrogenase [NADP] cytoplasmic;Isocitrate dehydrogenase [NADP], mitochondrial 0 ;;; 156.93 0.011928 9295000.0 33710.5 33073.0 37939.7 44222.3 46029.8 37997.6 36933.3 31916.6 31060.700000000004 29129.6 False True 39417.021837275635 36356.26886815758 38844.3263351135 41744.66790163099 37010.591117684075 36004.938965048146 33434.7104500637 31078.823068433005 31514.90397642875 34410.56589021329 1.1454918225708757 1.0565437657768268 1.1288488093757625 1.2131351758299211 1.0755589209362655 1.0463338231612258 0.971640819762655 0.9031767500595546 0.9158496281920171 1.0 15.070563997293956 -7.057359989737517 1.688514449997918 0.9329524254814004 1.1285045415434274 0.776128603190896 0.045052138661060226 0.17320263933850855 0.9873462590618846 0.02292396220077825 0.016562283661951244 8.762741702257676e-08 7.057359989737517 0.19555211606202694 IWYEHR ddPTM_PC-9_Lapatinib_30min_R1 2 IWYEHR 6 0 O75874;H0YL11;P48735-2;P48735 O75874 IDH1;IDH2 Isocitrate dehydrogenase [NADP] cytoplasmic;Isocitrate dehydrogenase [NADP], mitochondrial 0 ; 110.54 0.024037 15252700.0 29149.0 24671.0 29069.0 23788.0 23518.0 26967.0 20114.2 22772.0 29052.0 18385.300000000003 False True 28733.329914728078 24613.875815281714 26679.05902958497 25537.448874441736 22134.717478166996 25813.684273147344 21155.614856463533 23830.070253273163 25779.85782887748 21563.174608127654 1.3325185385225156 1.1414773688288078 1.237250985276028 1.1843084025677781 1.0265055067459277 1.1971189188171567 0.9810992695152363 1.1051281031825 1.1955502052633966 1.0 14.39628197202969 -1.5228787452808774 0.324883286187577 1.068777274401524 3.3616270674156716 0.4486383221437995 0.07920522626440317 55.91764603203775 0.7972691524769545 0.07184137049518396 76.57231356461921 0.02999999999996271 1.5228787452808774 2.2928497930141476 IY(ph)LY(ph)DT(ph)S(ph)NGKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IYLYDTSNGKK 11 1 Q5SZR4;F6TB26;Q9Y2W6-3;Q9Y2W6 Q5SZR4 TDRKH Tudor and KH domain-containing protein 4 IY(1)LY(1)DT(1)S(1)NGKK 44.188 0.044835 0.0 6527.7 7014.0 21988.0 9651.8 18386.0 18176.0 12403.0 11033.0 12738.0 10157.0 True False 7632.710682048147 7710.303566088868 22512.277309954367 9111.040937557791 14783.395285005337 17222.818562980687 11228.09805005619 10743.395440429791 12924.269152071573 11998.383697232235 0.6361449070685118 0.6426118517836253 1.8762758283140635 0.7593556905218416 1.2321155630666774 1.4354282207989078 0.9358008823010274 0.8954035569730995 1.077167515075628 1.0 13.550552452963146 -5.07913009809041 24.999999221969762 1.1470549686954676 0.6376136998831413 0.31621011489448725 0.3011538843050208 107.5480831936713 33977.28490082076 0.0744845616574758 0.19706783886762771 8.334314828827305e-06 5.07913009809041 -0.5094412688123263 IYEDGDDDMKR ddPTM_PC-9_Lapatinib_30min_R1 1 IYEDGDDDMKR 11 1 Q9HB71;Q9HB71-3 Q9HB71 CACYBP Calcyclin-binding protein 0 61.765 0.036662 9205800.0 36377.0 33260.0 58303.0 34246.0 52131.0 47031.0 28953.0 35410.0 71429.0 28974.0 False True 35858.257309275206 33182.98851348829 53509.55239608836 36764.56508130706 49064.75707348938 45019.59376461573 30452.04467188299 37055.27787056043 63383.913839284316 33982.1172945718 1.0552096268293176 0.9764838437182619 1.5746385645203989 1.0818797652487568 1.4438404955222386 1.3248024946287567 0.8961196975430166 1.0904346409421501 1.8652137914140232 1.0 15.052488123631806 -5.1569072389125346 18.83678669198933 1.2741433648823421 1.0157806600092572 0.1306742022375521 0.27620955669542574 10.257839885739497 1837.7675309507017 0.06870880591224746 0.18179143462932554 6.967753226664266e-06 5.1569072389125346 -0.258362704873085 IYGADDIELLPEAQHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IYGADDIELLPEAQHK 16 0 V9GZ78;V9GYY3;A0A384N5Y3;F5H2F4;P11586 V9GZ78 MTHFD1 C-1-tetrahydrofolate synthase, cytoplasmic;Methylenetetrahydrofolate dehydrogenase;Methenyltetrahydrofolate cyclohydrolase;Formyltetrahydrofolate synthetase;C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed 0 ; 128.71 4.7166e-05 0.0 40391.0 36831.0 42824.0 46097.0 48447.0 49339.0 45752.0 43483.0 44443.0 35563.0 False True 47228.3985413862 40487.33827240082 43845.08657092441 43514.33453849042 38954.15812969944 46751.5759836545 41418.03934420466 42341.61732404682 45092.894797104454 42010.290383446874 1.1242102377848688 0.9637481174934669 1.043674922756556 1.035801803351404 0.927252770074838 1.1128601006308638 0.9859022388601347 1.0078868043418832 1.0733773650579717 1.0 15.35845513760218 -4.742043524315587 24.951550029956987 1.0176528478637246 1.1242106071993947 0.2881459116362878 0.05066475481537109 1713.9613648846625 2204787.0724873855 0.011877906223545518 0.4409959356233109 1.8111585720367576e-05 4.742043524315587 0.10655775933567013 IYGADDIELLPEAQHK ddPTM_PC-9_Lapatinib_30min_R1 2 IYGADDIELLPEAQHK 16 0 V9GZ78;V9GYY3;A0A384N5Y3;F5H2F4;P11586 V9GZ78 MTHFD1 C-1-tetrahydrofolate synthase, cytoplasmic;Methylenetetrahydrofolate dehydrogenase;Methenyltetrahydrofolate cyclohydrolase;Formyltetrahydrofolate synthetase;C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed 0 ; 198.16 4.4656e-12 9206000.0 70963.0 63266.0 72858.0 69665.0 78735.0 69699.0 66416.0 62674.0 65665.0 71406.0 False True 69951.05460697967 63119.51146405146 66867.89648001308 74788.39649562741 74103.96209896584 66718.13624630464 69854.69550401624 65586.06284268579 58269.116216895236 83748.43195748556 0.8352521112573181 0.7536799195965094 0.7984375936012533 0.8930124988321374 0.8848399948142829 0.7966493782256573 0.8341015332618718 0.7831318307664578 0.6957636681063502 1.0 16.353774558325583 -5.547169189081515 24.817395527939567 0.83279498674092 0.7898641351266973 0.0592817334380048 0.07759764000585012 650.85083563445 664967.082719048 0.020903299121529013 0.0362072915859881 2.8368136692430985e-06 5.547169189081515 -0.04293085161422272 IYHLPDAES(ph)DEDEDFK ddPTM_PC-9_AZD4547_30min_R2 2 IYHLPDAESDEDEDFK 16 0 Q15019-2;Q15019-3;Q15019;B5MCX3;H7C2Y0 Q15019-2 SEPT2 Septin-2 1 IYHLPDAES(1)DEDEDFK;IYHLPDAES(1)DEDEDFK 122.49 0.00026081 0.0 18037.7 27384.5 19872.4 18772.7 21298.5 26929.1 23180.0 25866.7 24822.1 20549.6 True False 23773.31339253265 36236.00409191538 19608.878991604513 14444.944050323782 18341.570913870906 25245.219119967674 25242.975094389858 21869.595872633487 26134.14553067849 19830.164758811432 1.1988459844726758 1.8273173487282348 0.9888409516563098 0.7284328812197712 0.924932855422743 1.27307157691416 1.2729584146885755 1.1028448900262335 1.3178985575027014 1.0 14.27540904378957 -5.2815005767318315 24.922934516394054 1.0760421619605796 1.513081717831129 0.38337905300944675 0.2216642567291947 717.7766605221603 891725.4706447931 0.06068961452225242 0.12658424006031382 5.229972716548541e-06 5.2815005767318315 0.43703955587054955 IYHLPDAES(ph)DEDEDFK ddPTM_PC-9_Lapatinib_30min_R1 1 IYHLPDAESDEDEDFK 16 0 Q15019-2;Q15019-3;Q15019;B5MCX3;H7C2Y0 Q15019-2 SEPT2 Septin-2 1 IYHLPDAES(1)DEDEDFK 141.22 1.9841e-07 0.0 15572.0 19025.0 18076.0 16013.0 19401.0 19741.0 21351.0 21180.0 14280.0 16910.0 True False 15349.940424444934 18980.948781392526 16589.861055377824 17190.649437802076 18259.871323833577 18896.723448518624 22456.450308754647 22164.100121391413 12671.63602493358 19832.870968841333 0.7739646190690516 0.9570449387389638 0.8364830831321154 0.8667756405418887 0.9206872445507746 0.9527981842975001 1.132284395135486 1.1175437059118967 0.6389209129047178 1.0 14.275605914035339 -6.594319613613335 2.477450732864337 0.986774059959187 0.8648894122727312 0.12445653702516246 0.13334209339021638 0.588787177359341 7.3371272608014735 0.04824843957893328 0.049423831532752226 2.5449566341077763e-07 6.594319613613335 -0.1218846476864558 IYHLPDAES(ph)DEDEDFKEQTR ddPTM_PC-9_AZD4547_30min_R2 12 IYHLPDAESDEDEDFKEQTR 20 1 Q15019-2;Q15019-3;Q15019;B5MCX3;H7C2Y0 Q15019-2 SEPT2 Septin-2 1 IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(0.999)DEDEDFKEQT(0.001)R;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IY(0.001)HLPDAES(0.998)DEDEDFKEQTR;IYHLPDAES(0.991)DEDEDFKEQT(0.009)R;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(0.996)DEDEDFKEQT(0.004)R 113.7 1.0466e-05 2493838700.0 1210775.3 1233712.0 1244104.3 1518302.0 1353901.0 1335256.0 1314257.8 1300324.0 1227344.3 1281090.0 True False 1595776.6597092575 1632485.277446917 1227606.6640986905 1168280.931432063 1165935.2161823944 1251762.231238754 1431224.1981452834 1099388.8042729145 1292219.2140249508 1236239.4290334485 1.290831389318259 1.3205251661672632 0.9930169150635266 0.9450280455344167 0.9431305852248854 1.012556469111685 1.1577241143847705 0.88930087364425 1.0452823164160603 1.0 20.237526754012322 -5.262713157137689 24.779022864075728 0.9966377794972645 1.3056783043444284 0.7664097371300098 0.06788341313646785 42.040645758706006 817845.9596350315 0.017836894440464653 0.040730934108901634 5.461184423625477e-06 5.262713157137689 0.30904052484716393 IYHLPDAES(ph)DEDEDFKEQTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 11 IYHLPDAESDEDEDFKEQTR 20 1 Q15019-2;Q15019-3;Q15019;B5MCX3;H7C2Y0 Q15019-2 SEPT2 Septin-2 1 IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IY(0.001)HLPDAES(0.991)DEDEDFKEQT(0.008)R;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(0.997)DEDEDFKEQT(0.002)R 102.15 0.00011297 350010300.0 727353.4 738930.7 606910.6 855433.8 839239.3 715786.5 812798.7 735809.5 682803.6 651468.4 True False 850479.9647355169 812286.8564731312 621381.6504252689 807506.6175397977 674796.3836947221 678249.3958698828 735804.522983005 716495.2802796105 692788.3109124992 769574.463898984 1.105130178601083 1.0555013121897892 0.8074353809468824 1.04928977690948 0.876843522426567 0.8813304334886445 0.9561186831162687 0.9310278782504655 0.9002225819741286 1.0 19.553701402680005 -5.06930123486337 7.698487663827663 0.9251169747224668 1.0932367784943149 0.4915417698180292 0.06394781643588641 0.18972040173280708 18.980444899857336 0.015185099583650616 0.04106134769554588 8.525085928187524e-06 5.06930123486337 0.1681198037718481 IYHLPDAES(ph)DEDEDFKEQTR ddPTM_PC-9_Lapatinib_30min_R1 12 IYHLPDAESDEDEDFKEQTR 20 1 Q15019-2;Q15019-3;Q15019;B5MCX3;H7C2Y0 Q15019-2 SEPT2 Septin-2 1 IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(0.999)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(0.999)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(0.994)DEDEDFKEQT(0.006)R 131.61 5.2998000000000005e-06 2269110600.0 1845893.0 1643814.0 1515372.0 1421759.0 1536006.0 1556771.0 1325336.0 1389947.0 1390581.0 1381305.0 True False 1819570.2273246807 1640007.8496786323 1390783.9636650789 1526319.899708987 1445661.1469839867 1490191.533340449 1393955.4131611479 1454529.0118709938 1233959.124312897 1620061.7287767841 1.1231487016846784 1.0123119511729397 0.8584759080230728 0.942136878241932 0.8923494218183419 0.9198362672671784 0.8604335183040487 0.8978232039153381 0.7616741401851329 1.0 20.627617354102895 -4.983938493648593 2.5981934275749192 0.8894735259377614 1.1307898707047281 0.6123963629138892 0.05902120118092323 0.207905026839688 2.442977855991558 0.014862357062561397 0.09086149148817485 1.0376753647410047e-05 4.983938493648593 0.24131634476696673 IYHPNIDEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IYHPNIDEK 9 0 A0A1B0GUS4;P68036-2;P68036;P68036-3 A0A1B0GUS4 UBE2L3 Ubiquitin-conjugating enzyme E2 L3 0 66.435 0.040666 4187300.0 47444.0 44676.0 45998.0 67603.0 72144.0 63248.0 62397.0 64432.0 54394.0 41410.0 False True 55475.332138286394 49111.138026602 47094.766768386406 63815.42308188316 58007.901090037274 59931.16353825945 56486.304444840454 62740.728271347056 55189.40934666204 48917.30519862037 1.1340635366776293 1.0039624592400298 0.9627424605089373 1.3045572077769108 1.185835991056868 1.225152597734466 1.154730503151951 1.2825875836086849 1.1282185133170124 1.0 15.578057309096039 -5.752570508710777 24.99999930315736 1.1954814152926125 1.030626778470076 0.36141396411105087 0.0899304388651827 178.8638566045713 504184.6190482139 0.022995844552240133 0.0390925663325911 1.7677851904323596e-06 5.752570508710777 -0.16485463682253654 IYHPNIDEK ddPTM_PC-9_Lapatinib_30min_R1 2 IYHPNIDEK 9 0 A0A1B0GUS4;P68036-2;P68036;P68036-3 A0A1B0GUS4 UBE2L3 Ubiquitin-conjugating enzyme E2 L3 0 ; 86.882 0.0095009 8341800.0 116989.0 105829.0 110858.0 104720.0 112035.0 113593.0 102456.0 98971.0 108449.0 98480.0 False True 115320.71540684513 105583.95945261435 101743.68316425514 112421.45813567913 105445.32156928485 108734.8921882163 107760.67035894195 103569.55397139894 96234.33160140201 115502.13678364866 0.9984292812076425 0.9141299234176731 0.8808813931714096 0.9733279510340137 0.912929617629485 0.9414102216298531 0.9329755566409343 0.8966895059733736 0.8331822620880348 1.0 16.817560016109816 -7.757927230289506 21.55892336116278 0.8987018754383169 0.9340358315962899 0.04162573315765272 0.048960376028705496 37.85860135446339 232423.4548772683 0.023044667479191008 0.012565542986482672 1.746114704684554e-08 7.757927230289506 0.03533395615797297 IYHPNVDK ddPTM_PC-9_AZD4547_30min_R2 1 IYHPNVDK 8 0 F8VSD4;F8VV71;P61088;Q5JXB2;F8VQQ8 F8VSD4 UBE2N;UBE2NL Ubiquitin-conjugating enzyme E2 N;Putative ubiquitin-conjugating enzyme E2 N-like 0 93.649 0.0059308 6620000.0 78706.0 73194.0 99084.0 110120.0 97022.0 101080.0 84962.0 117810.0 85764.0 100050.0 False True 103732.87081350056 96852.52911331796 97770.08141966457 84733.5353370401 83552.17002162518 94759.45162097277 92523.45340679678 99605.17150448076 90297.30994932391 96547.27995285005 1.0744256167979012 1.0031616546899818 1.0126653124501455 0.8776377271158823 0.8654015945599796 0.981482354212875 0.9583227352648531 1.0316724774962491 0.935265188138098 1.0 16.558947993942233 -5.1034816144720105 1.7897806370255125 0.9513659039798137 1.0715265269839218 0.3432714253768616 0.050812212010863424 0.6056496845649455 3.0293046606543186 0.015442507390398937 0.09946097958638432 7.879857895268695e-06 5.1034816144720105 0.12016062300410812 IYIDSNNNPER ddPTM_PC-9_AZD4547_30min_R2 1 IYIDSNNNPER 11 0 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 118.03 0.0029212 0.0 5781.3 5970.5 11585.0 14942.0 19556.0 10236.0 8713.3 10120.0 15316.0 5775.7 False True 7619.633141489712 7900.34736550899 11431.375330495475 11497.352751598743 16840.986961131508 9595.941301862646 9488.766820101257 8556.18653446519 16125.57249176629 5573.494500986258 1.3671195226157271 1.4174854508443462 2.0510247796014935 2.062862491308501 3.021620808659883 1.7217100151735318 1.702480700110527 1.5351565401116176 2.893260680334894 1.0 12.444366444981261 -5.251858107112722 6.886273643581876 2.0365451621332302 1.3879000880401626 0.15096577054750926 0.5694605419020267 0.24989542901348688 70.53885988102527 0.14439661840743015 0.3542004697959755 5.599405156281762e-06 5.251858107112722 -0.6486450740930676 IYIDSNNNPER ddPTM_PC-9_Lapatinib_30min_R1 2 IYIDSNNNPER 11 0 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 ; 101.66 0.01677 22549000.0 44802.0 49310.0 39481.0 40515.0 43270.0 40969.0 37204.0 39386.0 46828.0 33951.0 False True 44163.115264319415 49195.82572459735 36235.02458106725 43494.60825407801 40724.9436720931 39216.851373403566 39130.2410794299 41216.01734566207 41553.737519298964 39819.38511313613 1.109085816841263 1.2354742692490246 0.909984533365222 1.0922973353430676 1.0227416509919494 0.9848683313913406 0.9826932527524418 1.0350741787839712 1.043555479353464 1.0 15.281183322830909 -5.252901311465225 24.99988855675926 1.011832821870172 1.172280045680152 0.601776169242844 0.05311906611678884 402.61194109136903 1178861.3471729953 0.012861494028791328 0.03292254450909568 5.585971152253297e-06 5.252901311465225 0.1604472238099801 IYIQT(ph)TTLT(ph)VSLSLSASVSLGMLYVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IYIQTTTLTVSLSLSASVSLGMLYVPK 27 0 O15303 O15303 GRM6 Metabotropic glutamate receptor 6 2 IY(0.053)IQT(0.53)T(0.205)T(0.205)LT(0.322)VS(0.126)LS(0.116)LS(0.058)AS(0.058)VS(0.137)LGMLY(0.19)VPK 42.321999999999996 0.027637000000000002 10037000.0 30699.0 27911.0 18896.0 25301.0 27668.0 22070.0 26357.0 23297.0 23249.0 24981.0 True False 35895.73436711186 30681.81962262711 19346.55230347906 23883.466996948733 22246.65401639986 20912.610347985465 23860.274151844802 22685.4784352119 23588.972642213204 29509.857550512803 1.2163980902201301 1.0397142571802738 0.6555962620410165 0.8093386068050912 0.7538719554413191 0.7086652421886076 0.8085526712896712 0.7687423904497189 0.7993590820231964 1.0 14.848909336182983 -5.051205721630504 3.97588521667322 0.77800528108014 1.1910737165086762 0.7266048498520068 0.08622215920243617 0.09264712084979305 2.9749367329859258 0.020608373621310693 0.07175890068021837 8.88780010538904e-06 5.051205721630504 0.4130684354285362 IYISNTFS(ph)PSKAEGDSAGTAGTPGGTPAGDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IYISNTFSPSKAEGDSAGTAGTPGGTPAGDK 31 1 Q92925-3;J3KMX2;B9EGA3;Q92925-2;Q92925 Q92925-3 SMARCD2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 1 IY(0.008)IS(0.023)NT(0.117)FS(0.563)PS(0.254)KAEGDS(0.019)AGT(0.01)AGT(0.005)PGGTPAGDK 55.707 0.00080066 9231300.0 34802.0 40607.0 32146.0 36993.0 38115.0 33239.0 42975.0 35917.0 34443.0 27134.0 True False 40693.29122916794 44638.19459768617 32912.48255438389 34920.40214292418 30646.639360816873 31495.88832608471 38904.096887943604 34974.21680720718 34946.66371524582 32053.17940737418 1.2695555318236544 1.3926292312648607 1.0268086711801205 1.0894520540102914 0.9561185482200958 0.9826135474984656 1.2137359727563655 1.0911309721481477 1.0902713665654635 1.0 14.968179846775755 -5.265071266640258 24.999677624897803 1.0601230121682752 1.331092391791935 0.6852597892536516 0.07446502592246466 165.2332158665304 1137372.9794500063 0.02025807299062164 0.045007849846658114 5.4316119278318715e-06 5.265071266640258 0.27096937962365986 IYISNTFS(ph)PSKAEGDSAGTAGTPGGTPAGDK ddPTM_PC-9_Lapatinib_30min_R1 2 IYISNTFSPSKAEGDSAGTAGTPGGTPAGDK 31 1 Q92925-3;J3KMX2;B9EGA3;Q92925-2;Q92925 Q92925-3 SMARCD2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 1 IY(0.004)IS(0.037)NT(0.223)FS(0.531)PS(0.171)KAEGDS(0.007)AGT(0.003)AGT(0.02)PGGT(0.004)PAGDK;IY(0.001)IS(0.01)NT(0.222)FS(0.542)PS(0.222)KAEGDS(0.002)AGTAGTPGGTPAGDK 79.82 3.5187e-07 21077000.0 72637.0 98662.0 90617.0 102265.0 110889.0 109779.0 107748.0 103451.0 105682.0 87190.0 True False 71601.18306000561 98433.554200775 83166.82005173541 109785.90924603964 104366.72703616197 105084.00807734787 113326.66422498699 108257.71112644284 93778.98027920377 102260.67532662784 0.7001829670233094 0.9625748498762722 0.8132825231800465 1.0735887367785872 1.020594932536943 1.0276091737288269 1.1082135323575129 1.0586445941282907 0.917058096669781 1.0 16.641891933123297 -3.9686747645572376 0.6928257794273488 1.0345885274331577 5.4880501931499275e-12 0.6016043758598402 0.07591474039062898 5.576451372791143 0.8879210709474399 0.03047420792222818 5.871354220442714 0.0001074794005218509 3.9686747645572376 -1.0345885274276696 IYISNTFSPS(ph)KAEGDSAGTAGTPGGTPAGDK ddPTM_PC-9_AZD4547_30min_R2 1 IYISNTFSPSKAEGDSAGTAGTPGGTPAGDK 31 1 Q92925-3;J3KMX2;B9EGA3;Q92925-2;Q92925 Q92925-3 SMARCD2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 1 IY(0.004)IS(0.019)NT(0.105)FS(0.392)PS(0.469)KAEGDS(0.009)AGT(0.001)AGT(0.001)PGGTPAGDK 66.083 5.1011000000000003e-05 16098000.0 59155.0 55346.0 59732.0 63954.0 59857.0 67099.0 66575.0 60812.0 61890.0 63475.0 True False 77965.05949956304 73235.51214998092 58939.9146518045 49210.3933794503 51546.88875702851 62903.2889227903 72500.04602713553 51414.90272074085 65161.379049060844 61252.75957028636 1.2728415837346827 1.1956279629482582 0.9622409678403482 0.8033987974530735 0.84154394216116 1.0269462039601658 1.1836208937483563 0.8393891651810926 1.0638113206032687 1.0 15.902487221683996 -5.196605748482706 3.817843704586824 0.9584786756893677 1.253392752111334 0.4932856226827489 0.10996038990512391 0.1974202294763047 5.689081078491435 0.03048995783288987 0.09065961188267303 6.359079456554709e-06 5.196605748482706 0.2949140764219662 IYISNTFSPSKAEGDSAGTAGT(ph)PGGTPAGDK ddPTM_PC-9_AZD4547_30min_R2 1 IYISNTFSPSKAEGDSAGTAGTPGGTPAGDK 31 1 Q92925-3;J3KMX2;B9EGA3;Q92925-2;Q92925 Q92925-3 SMARCD2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 1 IY(0.001)IS(0.009)NT(0.06)FS(0.171)PS(0.202)KAEGDS(0.083)AGT(0.098)AGT(0.342)PGGT(0.034)PAGDK 48.693999999999996 0.0095763 13513000.0 18101.0 16299.0 19265.0 18623.0 21798.0 17007.0 20766.0 19546.0 20886.0 19702.0 True False 23856.74147581086 21567.333005683104 19009.533512472615 14329.755072481823 18771.723960868523 15943.549601482797 22614.13377092752 16525.614822396896 21989.991320385918 19012.23897682208 1.2548096783811071 1.1343920635531646 0.9998576988037673 0.753712126696456 0.9873494638770969 0.8385940036268039 1.1894513738490522 0.8692092942100802 1.1566229178580194 1.0 14.214640820560135 -5.098551981219836 2.6531161553000846 0.9643766802847238 1.244738119058555 0.34485359689884965 0.12643460385469504 0.32329377795915376 4.132499995099336 0.03285482665969574 0.14372194499780064 7.969810932722888e-06 5.098551981219836 0.28036143877383113 IYISNTFSPSKAEGDSAGTAGT(ph)PGGTPAGDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IYISNTFSPSKAEGDSAGTAGTPGGTPAGDK 31 1 Q92925-3;J3KMX2;B9EGA3;Q92925-2;Q92925 Q92925-3 SMARCD2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 1 IY(0.001)IS(0.004)NT(0.082)FS(0.207)PS(0.172)KAEGDS(0.207)AGT(0.069)AGT(0.249)PGGT(0.007)PAGDK 53.482 0.0024492 10070000.0 52724.0 53063.0 42892.0 57599.0 60817.0 40568.0 54794.0 50962.0 46584.0 43407.0 True False 61649.131853532876 58330.743958850006 43914.70794881585 54371.91476847756 48900.34542848745 38440.54266411756 49603.51564579363 49624.30149870234 47265.20287173042 51276.34549037704 1.2022918416661048 1.1375760772537282 0.8564320941526002 1.0603703179018766 0.9536628431849635 0.7496739928810184 0.9673761882094865 0.9677815574437781 0.921774015283531 1.0 15.646005823043005 -5.138754278449661 4.837430030251934 0.9336322742810907 1.1868932203446754 0.58432465206481 0.07995320357813376 0.15010522379204985 5.177191286905661 0.020917773854061652 0.06026150009171325 7.265169006385512e-06 5.138754278449661 0.2532609460635846 IYKPLLFMDLLDER ddPTM_PC-9_AZD4547_30min_R2 1 IYKPLLFMDLLDER 14 1 A0A0J9YXV4;A0A0J9YWM9;H3BSH7;Q969X6-2;Q969X6 A0A0J9YXV4 CIRH1A Cirhin 0 26.124000000000002 0.045538999999999996 4750600.0 37016.0 45335.0 50691.0 57253.0 58606.0 57679.0 49301.0 56984.0 47360.0 53672.0 False True 48786.31801936994 59988.652175755764 50018.80421908901 44054.205400032355 50469.56851319665 54072.32301193196 53688.69349130779 48178.43216205183 49863.35291264374 51792.95961648539 0.9419488359155584 1.1582395101565452 0.9657452400763815 0.850582892467303 0.9744484363688013 1.0440091358424914 1.0366021538228336 0.9302119924947662 0.9627438416701821 1.0 15.660468380613853 IYLEENPEKSETIQDTDTQSLVGS(ph)PSTR ddPTM_PC-9_Lapatinib_30min_R1 1 IYLEENPEKSETIQDTDTQSLVGSPSTR 28 1 Q9NZN5-2;Q9NZN5;E9PMR6 Q9NZN5-2 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 IYLEENPEKSETIQDTDTQS(0.001)LVGS(0.414)PS(0.414)T(0.17)R 87.566 1.1118e-05 0.0 13948.0 9475.5 8607.5 8743.3 10307.0 12281.0 9348.5 9250.7 9210.0 9850.2 True False 13749.098962250062 9453.560061922988 7899.824575910853 9386.311448793782 9700.762524341668 11755.77025840927 9832.519587438199 9680.52129334068 8172.672814400438 11552.79394543353 1.1901102908257672 0.8182921037607266 0.6838020840000713 0.812471121109531 0.8396897382711552 1.0175694566989113 0.8510945173850951 0.837937674562879 0.7074195950349178 1.0 13.495954176972027 -4.7597150834092945 24.996586852699647 0.8358560273228104 1.1901107324508031 0.5209900160541918 0.10034238022364986 36.902496485234714 534806.1144165564 0.025638473448151483 0.1595798974679283 1.738941277815059e-05 4.7597150834092945 0.35425470512799273 IYNISGNGS(ph)PLADSK ddPTM_PC-9_AZD4547_30min_R2 3 IYNISGNGSPLADSK 15 0 Q53HL2 Q53HL2 CDCA8 Borealin 1 IYNISGNGS(0.953)PLADS(0.047)K;IYNISGNGS(1)PLADSK;IYNISGNGS(0.97)PLADS(0.03)K 219.72 4.5e-18 125776000.0 476968.0 553684.0 541602.0 560058.0 515718.0 575670.0 489919.0 566531.0 499778.0 536827.0 True False 628633.902449288 732651.5251192497 534420.0036035392 430945.28090984386 444119.45764066343 539673.2638963737 533520.841901138 478986.6515372626 526195.2447629914 518032.850127423 1.213502005316188 1.4142954929190994 1.0316334253167254 0.831887940704614 0.8573191015423467 1.0417742113528663 1.0298977019891795 0.9246260182524023 1.0157565193666014 1.0 18.982684061177274 -5.386017653811459 5.005632424542688 0.9551183169188104 1.310503144271126 0.7490842808565483 0.08114242833088285 0.10165256104296751 3.6707656197557426 0.022075648290055053 0.047528724278666265 4.111330084534565e-06 5.386017653811459 0.35538482735231547 IYNISGNGS(ph)PLADSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 IYNISGNGSPLADSK 15 0 Q53HL2 Q53HL2 CDCA8 Borealin 1 IYNISGNGS(0.861)PLADS(0.139)K;IY(0.001)NIS(0.006)GNGS(0.993)PLADSK;IYNISGNGS(1)PLADSK;IYNISGNGS(0.836)PLADS(0.164)K 239.8 2.6864e-32 78560100.0 349346.0 317301.0 326406.0 333698.0 398853.0 339562.0 343393.0 324867.0 282634.0 231249.0 True False 408483.37790198607 348800.54631074576 334188.75694164785 315001.9829235131 320700.6178402169 321754.7709552627 310864.3290899742 316339.585475039 286766.9875590045 273172.61313392327 1.4953306380743465 1.2768503486099676 1.2233611309264423 1.153124316928077 1.1739852474998764 1.1778441742896166 1.1379776527509093 1.1580208639727478 1.0497647779150414 1.0 18.059453328209813 -1.5228787452803376 0.4770038106622042 1.1053389547990358 11.173058003937763 0.8543798348686056 0.048697706185391536 35.64681248749145 0.4025534649101349 0.02781899296004728 355.24269733075096 0.029999999999999995 1.5228787452803376 10.067719049138727 IYNISGNGS(ph)PLADSK ddPTM_PC-9_Lapatinib_30min_R1 2 IYNISGNGSPLADSK 15 0 Q53HL2 Q53HL2 CDCA8 Borealin 1 IYNIS(0.026)GNGS(0.959)PLADS(0.015)K;IYNISGNGS(0.57)PLADS(0.43)K 214.24 1.2432e-17 38600000.0 125859.0 138973.0 146665.0 118100.0 138544.0 138218.0 116146.0 129006.0 132291.0 92671.0 True False 124064.22758028623 138651.21655697539 134606.7698432721 126785.46797005058 130395.1143079839 132306.73834189496 122159.47157325728 135000.0897195574 117390.99449401164 108689.05887365434 1.1414601328410134 1.2756685722907084 1.2384574053561896 1.1664970631260356 1.1997078239453869 1.2172958319171299 1.1239353145495687 1.2420761677262138 1.0800626641773838 1.0 16.72984719398167 -8.467385978294862 3.738406207870604 1.0008004687889804 1.2009035208765937 0.6893425467907137 0.044617928153108506 0.10909004835055493 3.177278320479954 0.042108077241362236 0.011089625767123554 3.4088981185874344e-09 8.467385978294862 0.20010305208761325 IYNISGNGSPLADS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 IYNISGNGSPLADSK 15 0 Q53HL2 Q53HL2 CDCA8 Borealin 1 IYNISGNGS(0.113)PLADS(0.887)K 247.02 3.0293999999999996e-40 34829000.0 38670.0 41371.0 46239.0 48876.0 48571.0 47628.0 43679.0 53113.0 38924.0 49497.0 True False 50966.25561403271 54743.366696000725 45625.840647974095 37608.39332667249 41827.75504648797 44649.81363082396 47566.34638256495 44905.606265321105 40981.44317507904 47764.125095714255 1.0670404935064073 1.1461189038070059 0.9552324167258321 0.7873774145618547 0.8757148793716952 0.9347981050914355 0.9958592623071609 0.9401534347239695 0.857996311938229 1.0 15.543639818290693 -5.371938983081556 4.908413373230859 0.9108451990525079 1.1050547790583465 0.5935134103741789 0.06285257817721454 0.14593675001777948 5.298094465839513 0.01746100324961826 0.03782795188018065 4.246792257622701e-06 5.371938983081556 0.19420958000583854 IYNISGNGSPLADS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IYNISGNGSPLADSK 15 0 Q53HL2 Q53HL2 CDCA8 Borealin 1 IYNISGNGS(0.147)PLADS(0.853)K;IYNISGNGS(0.168)PLADS(0.832)K 226.67 2.2281e-24 48321800.0 279428.0 311423.0 272730.0 319068.0 336324.0 260307.0 297354.0 261695.0 238013.0 197676.0 True False 326729.64144543273 342339.017317094 279232.91753428464 301191.6543924125 270423.72652203526 246656.04267571584 269186.4764634689 254825.78353877232 241493.4898486431 233513.0939976451 1.3991919504468031 1.466037777395671 1.1957912627250813 1.2898276890436384 1.158066650107263 1.0562835618896955 1.152768231772834 1.0912697835323193 1.0341753677036991 1.0 17.833143924225375 -4.634734002504831 0.33683699121828253 1.0132178665096703 1.8482725600195433 0.8441013964710756 0.05857115504084212 2.7181282933185003 0.23038654146555063 0.05690699765409619 0.9497342445925275 2.318814446926176e-05 4.634734002504831 0.835054693509873 IYNISGNGSPLADS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 2 IYNISGNGSPLADSK 15 0 Q53HL2 Q53HL2 CDCA8 Borealin 1 IYNISGNGS(0.118)PLADS(0.882)K;IYNISGNGS(0.499)PLADS(0.501)K 252.1 2.7052999999999994e-41 102996000.0 402100.0 428410.0 427720.0 407880.0 405620.0 406850.0 410610.0 386270.0 444890.0 309360.0 True False 396365.98026389064 427418.0429664315 392554.51264694723 437876.85584779247 381762.2290796028 389449.97391367273 431869.3766698394 404217.5143479624 394781.8033006095 362832.4638037115 1.092421488718607 1.1780038601994005 1.0819167296433403 1.2068293207762113 1.0521721928557421 1.0733603322892324 1.1902721496924158 1.1140610465513354 1.0880553497389975 1.0 18.468944018708164 -8.666466192652335 2.23232925238798 1.0002355964610283 1.1249078962847572 0.36150485664678667 0.04975631423471447 0.5975897058189262 5.972791550776963 0.046372610016715526 0.012692809602781645 2.1554294249191664e-09 8.666466192652335 0.12467229982372885 IYPSREEYEAHQDR ddPTM_PC-9_Lapatinib_30min_R1 2 IYPSREEYEAHQDR 14 1 Q06587;Q06587-2 Q06587 RING1 E3 ubiquitin-protein ligase RING1 0 ; 58.595 0.028281 7140700.0 25128.8 19343.2 28823.0 20978.0 20927.0 20831.2 15438.6 15936.8 24432.0 16442.1 False True 24770.45870394247 19298.41200884268 26453.284199997488 22520.792100556526 19696.115004065003 19940.298135898964 16237.935166350031 16677.28190814876 21680.21087963425 19284.095077278882 1.2845020004660623 1.000742421747374 1.371766945453695 1.167842826448788 1.0213657900531499 1.0340282007525072 0.8420377052321252 0.8648205602241845 1.1242534737955399 1.0 14.235123827400844 -6.386220567068615 2.2277365036297923 0.9564663340338049 1.206901628063992 0.4815073083928446 0.11543497139276676 0.2708254764590977 2.6407288239475175 0.039909626267475226 0.04700581811244654 4.109409616847084e-07 6.386220567068615 0.25043529403018705 IYPVGY(ph)FTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IYPVGYFTK 9 0 Q2L6G8;G8JLG2;Q15517 Q2L6G8 CDSN Corneodesmosin 1 IYPVGY(0.584)FT(0.416)K 92.46700000000001 0.010159 5748500.0 17234.0 15696.0 15567.0 18166.0 20594.0 16021.0 20329.0 19362.0 17858.0 15095.0 True False 20151.37581298432 17254.195148749783 15938.17631817626 17148.217914966637 16558.753535265976 15180.83055664139 18403.289950785464 18853.76801573476 18119.13946598321 17831.604008045742 1.1300932773009023 0.9676187930690122 0.8938161878754624 0.9616755681221523 0.9286182851410648 0.8513440826631017 1.0320602645999637 1.057323166621904 1.01612504729287 1.0 14.122148863239785 IYPVGYFT(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 IYPVGYFTK 9 0 Q2L6G8;G8JLG2;Q15517 Q2L6G8 CDSN Corneodesmosin 1 IYPVGY(0.351)FT(0.649)K 97.071 0.011984 5434300.0 27915.0 24436.0 32491.0 38228.0 31675.0 35374.0 31784.0 31618.0 23332.0 29266.0 True False 36791.38933192976 32334.459127975493 32060.148110757724 29415.125216712404 27277.473000298676 33162.05818797275 34612.71442623327 26732.164609359737 24565.281886777953 28241.40624787713 1.3027463650006919 1.1449309161227066 1.1352178368656003 1.0415602168862785 0.965868086060661 1.1742353725911046 1.2256016617031975 0.9465592603544365 0.8698321064881284 1.0 14.785524307263614 -1.5228787452803376 0.39135614872622904 1.0129802659738532 5.106031945841311 0.42748272795438247 0.09860776473590753 82.22193792564313 1.1051049327464804 0.0808053367467589 257.67296297956403 0.029999999999999995 1.5228787452803376 4.093051679867457 IYQY(ph)IQSR ddPTM_PC-9_AZD4547_30min_R2 5 IYQYIQSR 8 0 A0A2R8Y6L5;A0A2R8Y6I6;Q13627-5;Q13627-2;Q13627;A0A2R8Y443;A0A2R8YDF3;Q13627-4;Q13627-3;Q9Y463-2;Q9Y463-3;Q9Y463 A0A2R8Y6L5 DYRK1A;DYRK1B Dual specificity tyrosine-phosphorylation-regulated kinase 1A;Dual specificity tyrosine-phosphorylation-regulated kinase 1B 1 IYQY(1)IQSR;IYQY(1)IQSR;IYQY(1)IQSR;IYQY(1)IQSR;IYQY(1)IQSR 158.07 5.3496000000000004e-05 174294000.0 76181.5 76133.8 106120.0 140015.0 118559.0 100973.0 88687.0 117482.0 86927.0 91504.0 True False 100405.63232636258 100742.56197239572 104712.77946242387 107736.70496018603 102099.12932730585 94659.14234788752 96579.97119051569 99327.85636779033 91521.78375501225 88300.4728116498 1.137090540166572 1.1409062575155813 1.1858688422403185 1.2201147007445234 1.1562693389546104 1.0720117269337974 1.0937650514796966 1.1248847622782565 1.0364812422945198 1.0 16.43013354246505 -6.717104624873839 4.814911590011774 1.074651255312093 1.1717501960812555 0.6390784656722814 0.038322346171088706 0.14311643803646065 7.3177096839168625 0.01333193142541387 0.012963673073198094 1.9182065743170983e-07 6.717104624873839 0.09709894076916248 IYQY(ph)IQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 IYQYIQSR 8 0 A0A2R8Y6L5;A0A2R8Y6I6;Q13627-5;Q13627-2;Q13627;A0A2R8Y443;A0A2R8YDF3;Q13627-4;Q13627-3;Q9Y463-2;Q9Y463-3;Q9Y463 A0A2R8Y6L5 DYRK1A;DYRK1B Dual specificity tyrosine-phosphorylation-regulated kinase 1A;Dual specificity tyrosine-phosphorylation-regulated kinase 1B 1 IY(0.004)QY(0.993)IQS(0.004)R;IYQY(1)IQSR;IYQY(1)IQSR;IYQY(0.999)IQSR;IY(0.001)QY(0.997)IQS(0.002)R 166.68 0.0005752000000000001 210673000.0 113837.0 120006.0 140547.0 137136.0 159841.0 128465.0 139008.0 121925.0 119411.0 98685.0 True False 133107.35571676315 131919.4025879759 143898.17350746557 129452.71452091064 128521.30347821952 121728.06925029236 125840.15590923236 118724.59794021613 121157.15997158256 116575.80930996987 1.1418094071544178 1.1316190157188453 1.2343742184525328 1.1104594965899113 1.1024697511341062 1.0441966474075497 1.0794705750198053 1.0184325431062007 1.0392993253808864 1.0 16.830908919842066 -6.497110914994255 1.292101091529065 1.0337689919623225 1.1647637523857621 0.7375324590727215 0.03391948043643486 0.22972214694601606 0.7948133053611279 0.014704460980930254 0.016885565503762384 3.183384409495934e-07 6.497110914994255 0.1309947604234396 IYQY(ph)IQSR ddPTM_PC-9_Lapatinib_30min_R1 6 IYQYIQSR 8 0 A0A2R8Y6L5;A0A2R8Y6I6;Q13627-5;Q13627-2;Q13627;A0A2R8Y443;A0A2R8YDF3;Q13627-4;Q13627-3;Q9Y463-2;Q9Y463-3;Q9Y463 A0A2R8Y6L5 DYRK1A;DYRK1B Dual specificity tyrosine-phosphorylation-regulated kinase 1A;Dual specificity tyrosine-phosphorylation-regulated kinase 1B 1 IYQY(1)IQSR;IYQY(1)IQSR;IY(0.002)QY(0.998)IQSR;IYQY(1)IQSR;IYQY(1)IQSR;IYQY(1)IQSR 171.53 5.3496000000000004e-05 261759200.0 153891.0 166270.0 175614.0 148227.0 151762.0 148409.0 130062.0 131699.0 166140.0 129328.0 True False 151696.48611984664 165885.01203059856 161175.69480964355 159128.10805077688 142835.65753557172 142061.89302827636 136795.97396174644 137818.21633083717 147427.56366823986 151682.17248127196 1.0000943659913393 1.0936355229951642 1.0625882539330305 1.0490890620018265 0.9416772927168319 0.9365760702419831 0.9018592740596229 0.9085986446288106 0.971950501872213 1.0 17.21069200706036 -6.259167230412419 4.710709621154788 0.9357498336911902 1.0562431551659108 0.6982834248412395 0.03452112966021222 0.09753337946465593 6.201842049161615 0.010385759708577616 0.012722884126209255 5.505956419816002e-07 6.259167230412419 0.12049332147472058 IYS(ph)S(ph)Y(ph)PKVQET(ph)LPVTY(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 IYSSYPKVQETLPVTYK 17 1 Q9NR99 Q9NR99 MXRA5 Matrix-remodeling-associated protein 5 5 IY(0.163)S(0.883)S(0.972)Y(0.97)PKVQET(0.993)LPVT(0.186)Y(0.833)K 54.501000000000005 0.014431 11764000.0 15968.0 19858.0 23372.0 21398.0 38487.0 24339.0 31985.0 34678.0 27788.0 29709.0 True False 18671.06701762409 21829.37100305003 23929.277118803588 20199.13943325202 30945.748631241197 23062.61999363925 28955.149248653317 33767.73924437817 28194.34693026887 35095.00652368539 0.5320149179919117 0.6220078913026424 0.6818427887355961 0.575555938980087 0.8817707046259163 0.6571481893891212 0.8250504022306329 0.9621807370683503 0.8033720384477117 1.0 15.098978151503646 -5.883345689910913 0.22765135870214256 1.0321646379677683 0.3233021944268719 0.7094861291716547 0.08363863694700331 3.6705061242953523 0.2715229131452854 0.1611957635624979 0.7454398798592591 1.3081402544308712e-06 5.883345689910913 -0.7088624435408963 IYS(ph)S(ph)YPKVQET(ph)LPVT(ph)Y(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 IYSSYPKVQETLPVTYK 17 1 Q9NR99 Q9NR99 MXRA5 Matrix-remodeling-associated protein 5 5 IY(0.174)S(0.698)S(0.668)Y(0.627)PKVQET(0.929)LPVT(0.929)Y(0.974)K 46.318999999999996 0.026927999999999997 9028600.0 14498.0 15706.0 9920.8 11916.0 18495.0 20811.0 20215.0 17670.0 19291.0 20353.0 True False 14291.255861392425 15669.633721973769 9105.150119395452 12792.342390610716 17407.16046256903 19920.96204281044 21261.633787245355 18491.012707506445 17118.244436764257 23870.988931332216 0.5986872141117802 0.6564300191772265 0.38143162587806967 0.5358949487769206 0.72921823694204 0.8345260475012365 0.890689273427549 0.7746228177097345 0.7171150087667904 1.0 14.542970715419287 -6.42613404031639 3.016154566863669 0.8306046757856637 0.5394648178670395 0.6862947824428303 0.09543757345870821 0.16467294019094264 2.8854456201661476 0.03273533831920348 0.036956321694382815 3.748572887229428e-07 6.42613404031639 -0.2911398579186242 IYSQS(ph)TLSLSTVANEAHNNLGVK ddPTM_PC-9_AZD4547_30min_R2 1 IYSQSTLSLSTVANEAHNNLGVK 23 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 IYS(0.062)QS(0.697)T(0.239)LS(0.002)LSTVANEAHNNLGVK 145.66 3.1729e-06 21391000.0 31659.0 29308.0 73421.0 86072.0 64084.0 67312.0 59176.0 52486.0 48232.0 64104.0 True False 41725.90345189193 38781.23785082279 72447.38956757089 66229.43019914386 55187.042770359614 63102.969999118635 64442.549360897974 44375.49470829449 50781.44505242042 61859.73847173907 0.6745244076800392 0.6269221113590739 1.1711557687989393 1.0706387035470755 0.892131847527485 1.0200975878348977 1.0417526965513906 0.7173566491647497 0.8209127019769116 1.0 15.916713113618032 -5.237549477222004 24.86140333091742 0.962289836817055 0.6507231511659433 0.5114785060411897 0.12348178625906654 641.4529673949507 667535.6757723346 0.03403233365976466 0.08992921297337525 5.786960563479534e-06 5.237549477222004 -0.3115666856511118 IYSQS(ph)TLSLSTVANEAHNNLGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IYSQSTLSLSTVANEAHNNLGVK 23 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 IYS(0.054)QS(0.711)T(0.231)LS(0.004)LSTVANEAHNNLGVK;IYS(0.062)QS(0.712)T(0.226)LSLSTVANEAHNNLGVK 215.83 8.1973e-38 34383000.0 56992.0 60660.0 69738.0 88030.0 73029.0 76849.0 78350.0 68672.0 83880.0 67619.0 True False 66639.61995669037 66681.92391202606 71400.81840283773 83097.96449711063 58719.49169306288 72818.90315506725 70928.12079512245 66869.43276399834 85106.58631463053 79877.78942829059 0.8342697066812966 0.834799315169945 0.8938757433558803 1.0403137729757896 0.73511663396466 0.9116289230868065 0.8879579830986358 0.8371467618546159 1.0654599598181675 1.0 16.28550678713139 -8.262409810466687 24.999999406260688 1.0327299355252215 0.8743006357760589 0.42656291358395204 0.07455293867649405 83.80461690331924 2158788.557457133 0.0586579839314222 0.018576987451112893 5.465000292539033e-09 8.262409810466687 -0.15842929974916264 IYSQS(ph)TLSLSTVANEAHNNLGVK ddPTM_PC-9_Lapatinib_30min_R1 2 IYSQSTLSLSTVANEAHNNLGVK 23 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 IYS(0.063)QS(0.695)T(0.239)LS(0.003)LSTVANEAHNNLGVK;IY(0.002)S(0.252)QS(0.537)T(0.204)LS(0.004)LSTVANEAHNNLGVK 150.06 1.5852e-06 24725000.0 88401.0 67989.0 78412.0 66271.0 53792.0 74146.0 58158.0 58918.0 59780.0 32383.0 True False 87140.38552924186 67831.57564773173 71965.26803907313 71144.79041357529 50628.06031914105 70974.94842276804 61169.13667072048 61655.545370733715 53046.946888692546 37980.358402364815 2.2943539554333467 1.785964601205771 1.8948022363736374 1.8731995538290003 1.3330063866903568 1.8687277163332099 1.6105465889155968 1.6233534375203469 1.3966942156446218 1.0 15.212965899119922 -1.5228787452803556 0.05831054819158125 6.787045977283808e-14 5.104479236976355 0.728651966835068 0.17874287642097567 197.11728274178577 0.8636269472068124 15.73555733777011 86.21550446848883 0.029999999999998753 1.5228787452803556 5.104479236976288 up IYVDDGLISLQVK ddPTM_PC-9_AZD4547_30min_R2 1 IYVDDGLISLQVK 13 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 134.2 0.00032993 0.0 4716.8 4509.0 6596.7 8714.6 7706.2 8183.8 6191.2 8273.2 5241.6 6413.4 False True 6216.644284465203 5966.446071699189 6509.223447792788 6705.583609227844 6636.327148694605 7672.065692280527 6742.2048060563675 6994.767039223069 5518.660275061517 6188.868818087033 1.0044879714200754 0.9640608400459529 1.0517630344287658 1.083490991056509 1.072300503332672 1.2396555683744397 1.0894082592851546 1.1302173700597418 0.8917074246158159 1.0 12.595460026950015 -5.450126327169682 3.3516931840022512 1.0851135069196567 0.9845987586435325 0.13101958676758874 0.08468030361519276 0.42213423664244676 9.109130338153676 0.023237631444775857 0.05219191701648174 3.547101964582747e-06 5.450126327169682 -0.10051474827612417 IYVDDGLISLQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 IYVDDGLISLQVK 13 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ; 186.81 0.00017481 3702100.0 23055.0 19844.3 20549.9 24287.0 25649.0 23720.0 21513.0 21174.6 20876.1 22343.0 False True 26957.756142993698 21814.31095759016 21039.88755192974 22926.278129516384 20623.262572887103 22476.08144332647 19475.132899367796 20618.78918634322 21181.37346879898 26393.609032909317 1.0213743830705746 0.8264997382658287 0.797158415345768 0.8686299058582844 0.7813733448568038 0.851572871875983 0.7378730538550032 0.781203857366923 0.8025190280870126 1.0 14.687901016226625 -4.761944852280323 5.664301840844998 0.816851639948194 1.0304110887547666 0.4131450118008906 0.06840384283149069 0.1266181563234029 13.737919435022059 0.015746451761031087 0.10578082953544636 1.7300360292516044e-05 4.761944852280323 0.21355944880657263 IYVDDGLISLQVK ddPTM_PC-9_Lapatinib_30min_R1 3 IYVDDGLISLQVK 13 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ;; 177.57 0.00010082 8937600.0 50991.5 45475.24 56007.9 44870.1 50521.1 49767.4 48088.0 46483.99 49603.71 45764.1 False True 50264.35185930413 45369.94487577041 51403.146658746125 48169.996836265724 47549.54822630425 47638.964315475714 50577.76134360889 48643.805873548525 44016.81782957687 53674.36370816981 0.9364685184270449 0.8452814666317995 0.9576852543278872 0.8974488658713943 0.8858893695476953 0.8875552689267289 0.942307609245313 0.9062763396325911 0.8200715348746097 1.0 15.711945563062299 -12.030190521092354 2.379977710317057 2.631577917489266 0.8988057911567453 0.3676263148947906 0.04024012518740978 7223500.233801004 2294084.842361224 60393901.3084326 0.009757431754739808 9.328449802983561e-13 12.030190521092354 -1.7327721263325206 KAALEEVER ddPTM_PC-9_AZD4547_30min_R2 1 KAALEEVER 9 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 62.303000000000004 0.03938 2275500.0 11391.0 9573.6 12942.0 16690.0 18578.0 12172.0 13532.0 15352.0 13702.0 13757.0 False True 15013.10105248116 12668.078978048214 12770.38062384743 12842.37835792953 15998.765379622699 11410.882915813996 14736.321785042443 12979.701153864595 14426.25974681259 13275.371617304918 1.1308987413136558 0.9542541891283046 0.9619603120714741 0.9673837183728277 1.2051463296716862 0.8595528053572155 1.1100496626273817 0.9777278955374096 1.0866934774170425 1.0 13.696464626487646 KAALPAATTPGPGLETAGPADAPAGAVVGGGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 KAALPAATTPGPGLETAGPADAPAGAVVGGGSPR 34 1 M0QXP1;Q10586 M0QXP1 DBP D site-binding protein 1 KAALPAATTPGPGLETAGPADAPAGAVVGGGS(1)PR 148.39 1.3637e-21 9125500.0 14773.0 12759.0 24608.0 27987.0 26525.0 23001.0 17694.0 24920.0 21466.0 19989.0 True False 19470.506702511124 16883.097234156136 24281.681841418438 21535.02954483967 22842.461604827844 21562.743833933444 19268.73172218008 21069.18660463168 22600.64893629244 19289.19119417808 1.0093998502325887 0.875262060715736 1.2588232236895036 1.1164298869793685 1.1842104407012266 1.1178666651633156 0.9989393297110262 1.0922794218033798 1.171674266109915 1.0 14.235505031251058 -5.246201032784976 24.985391711769854 1.1189426988173825 0.9423309504054248 0.4307862533733743 0.080541995389194 740.9946015827758 1214959.4048859233 0.020336826470246323 0.05336552868119773 5.672819525901812e-06 5.246201032784976 -0.1766117484119577 KAALPAATTPGPGLETAGPADAPAGAVVGGGS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KAALPAATTPGPGLETAGPADAPAGAVVGGGSPR 34 1 M0QXP1;Q10586 M0QXP1 DBP D site-binding protein 1 KAALPAATTPGPGLET(0.003)AGPADAPAGAVVGGGS(0.997)PR 94.443 6.1594e-16 5010000.0 11455.0 10587.0 11378.0 13967.0 16661.0 14995.0 16338.0 10293.0 14711.0 11873.0 True False 13394.10525343712 11638.007392954496 11649.294671305286 13184.474271624958 13396.39665198924 14208.635802811148 14790.34636312328 10022.819656334983 14926.120544522286 14025.48091338371 0.9549836712305455 0.8297759959053536 0.8305807653403908 0.9400372331649443 0.9551470452044057 1.0130587243716302 1.0545339909884803 0.714615043735918 1.0642145275944974 1.0 13.77576261915063 -5.892724274252764 5.7925955086044425 0.958308119908211 0.8681119380306175 0.15612815724940732 0.0975100952424742 0.40692367209552194 19.34790228035611 0.02738849494675848 0.04114649085143065 1.2801938182106891e-06 5.892724274252764 -0.09019618187759348 KAALPAATTPGPGLETAGPADAPAGAVVGGGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 KAALPAATTPGPGLETAGPADAPAGAVVGGGSPR 34 1 M0QXP1;Q10586 M0QXP1 DBP D site-binding protein 1 KAALPAATTPGPGLETAGPADAPAGAVVGGGS(1)PR;KAALPAATTPGPGLET(0.001)AGPADAPAGAVVGGGS(0.999)PR 126.06 8.0595e-23 12550700.0 41191.0 39665.0 37857.0 34591.0 39376.0 40950.0 31702.9 33329.0 38639.7 26940.9 True False 40603.60878649576 39573.15812951035 34744.54359224598 37134.937532193304 37059.98109619458 39198.663959112404 33344.321038518945 34877.58701349646 34287.69009192058 31597.598668507242 1.285021979438097 1.252410303221941 1.0995944330059246 1.1752455596951747 1.172873340312775 1.2405583212303095 1.055280225194854 1.103804987822012 1.0851359450328897 1.0 14.94752730122161 -1.5228787454004429 0.08992440413118155 0.886285828047505 1.9247061306619841 0.6546485602047147 0.05201544591988536 104.9358433514251 0.6812270672060518 1.0309138956339585 13.441283453947014 0.02999999999170342 1.5228787454004429 1.0384203026144792 KAALS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 KAALSSPR 8 1 Q68E01-4;Q68E01-3;Q68E01-2;Q68E01 Q68E01-4 INTS3 Integrator complex subunit 3 1 KAALS(0.855)S(0.145)PR 53.597 0.044527 17265000.0 173510.0 124330.0 132900.0 121400.0 124590.0 115620.0 120800.0 126400.0 153860.0 96738.0 True False 171035.71558216293 124042.12152381247 121973.47500883574 130328.16097852799 117261.8611533644 110675.20212338411 127054.4329210605 132273.0054458866 136530.6665823725 113459.03440471731 1.5074666947372835 1.093276724719377 1.075044183557448 1.1486803290925003 1.0335171788531365 0.9754639875445876 1.1198264958597068 1.1658217094820178 1.2033476866668622 1.0 16.791811965526783 -4.761442346827129 11.619392955836267 1.0925588844958454 1.5081681146883974 0.7666443670844064 0.06899694878473192 0.03107954165275696 188.50898692049958 0.01810516949439692 0.10145707647807745 1.7320389459738023e-05 4.761442346827129 0.415609230192552 KAAS(ph)EELLEK ddPTM_PC-9_AZD4547_30min_R2 1 KAASEELLEK 10 1 Q6ZV73-2;Q6ZV73;F8VY01 Q6ZV73-2 FGD6 FYVE, RhoGEF and PH domain-containing protein 6 1 KAAS(1)EELLEK 59.607 0.032925 3334600.0 35619.0 36770.0 40644.0 57284.0 57690.0 58840.0 56716.0 49610.0 55330.0 59003.0 True False 46945.101078775035 48655.1834234596 40105.034003682165 44078.05882897757 49680.73930188571 55160.725498397616 61763.61412654942 41943.91442438914 58254.63084156623 56937.32292911546 0.8245048882473749 0.8545393587266692 0.7043716132142571 0.7741505318726151 0.8725513730903035 0.9687973136192295 1.0847649827766312 0.7366681864654495 1.0231361055399595 1.0 15.797087041795699 -6.513118724091322 3.392768060201938 0.953038637974855 0.7890916314218978 0.4384948167250702 0.09204628177920679 0.24975846062299117 6.039983625878701 0.03117001544560811 0.033347167244271246 3.0681831173885694e-07 6.513118724091322 -0.16394700655295724 KAAS(ph)EELLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KAASEELLEK 10 1 Q6ZV73-2;Q6ZV73;F8VY01 Q6ZV73-2 FGD6 FYVE, RhoGEF and PH domain-containing protein 6 1 KAAS(1)EELLEK 58.885 0.034365 3406300.0 13769.0 16537.0 15230.0 17469.0 21268.0 23534.0 22055.0 21702.0 17248.0 16533.0 True False 16099.819749853841 18178.68407077441 15593.140960096634 16490.268565262144 17100.688073615464 22299.835610760765 19965.790735627605 21132.345495169702 17500.21936998983 19530.302024844015 0.824350782152455 0.9307938017368985 0.79840756892858 0.8443427318371872 0.875597727667606 1.1418070023901163 1.0222981042602217 1.0820286070480511 0.8960547229494061 1.0 14.25342663939246 -6.640301962186159 7.517649842988234 1.0327426184796533 0.8528245857859208 0.6316719714354261 0.06647807111577245 0.14539926775361478 8.980829713635343 0.021378239601601835 0.021349216279756795 2.2892753806975305e-07 6.640301962186159 -0.17991803269373252 KAAS(ph)EELLEK ddPTM_PC-9_Lapatinib_30min_R1 3 KAASEELLEK 10 1 Q6ZV73-2;Q6ZV73;F8VY01 Q6ZV73-2 FGD6 FYVE, RhoGEF and PH domain-containing protein 6 1 KAAS(1)EELLEK;KAAS(1)EELLEK;KAAS(1)EELLEK 74.649 0.011729999999999999 12233700.0 105656.0 72254.0 85531.0 94608.0 86834.0 76583.0 76102.0 74265.0 77053.0 79692.0 True False 104149.32606506278 72086.7003022726 78498.97133920799 101565.78792303642 81726.59484221245 73307.72361369237 80042.18919005425 77715.62301771184 68374.47973593888 93466.6560170849 1.1142939151051385 0.7712557972449102 0.8398607020332369 1.0866526336886502 0.8743930544308072 0.7843195288841013 0.8563715939021423 0.8314796562691416 0.7315387395847415 1.0 16.512164158683667 -6.516181549927671 24.791340406947285 0.8309828973731621 0.9380219562995561 0.16927363542497154 0.11484236566215736 521.1762132946734 1929272.0703100986 0.03656141169962412 0.037908755530100105 3.0466211316917124e-07 6.516181549927671 0.10703905892639398 KAAS(ph)LTEDR ddPTM_PC-9_AZD4547_30min_R2 1 KAASLTEDR 9 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 KAAS(0.852)LT(0.148)EDR 78.548 0.031497000000000004 12171000.0 35327.0 61911.0 51900.0 62714.0 51847.0 68064.0 51499.0 59847.0 51116.0 49134.0 True False 46560.25115275234 81922.52001440871 51211.7720891424 48256.25622164127 44648.93899436418 63807.94732024014 56082.311233217595 50599.02129724687 53817.887404617766 47413.833615225674 0.9819971852645294 1.7278189458213626 1.0801019066447546 1.0177674434269974 0.9416859087307882 1.345766466345171 1.18282591718566 1.067178446439698 1.135067200879863 1.0 15.533020425515605 KAAS(ph)LTEDR ddPTM_PC-9_Lapatinib_30min_R1 2 KAASLTEDR 9 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 KAAS(0.532)LT(0.468)EDR;KAAS(0.994)LT(0.006)EDR 88.441 0.0083797 0.0 151357.0 174831.0 149390.0 119072.0 156829.0 162765.0 167378.0 182373.0 136459.0 136163.0 True False 149198.6214245256 174426.18956108444 137107.73086207645 127828.95209254771 147604.62655767705 155803.92037374686 176044.01385315636 190846.71536536937 121089.55044302595 159698.59312420746 0.934251319975528 1.092221203385445 0.8585406306957213 0.8004388115875714 0.9242700494103653 0.9756123540335044 1.1023516889484184 1.1950431849887124 0.7582380537870307 1.0 17.284992077720275 -6.9686486773370016 4.385038174413239 1.0315503165553912 0.922192682956481 0.10136323959978244 0.12471011054170712 0.4310111102784552 19.20065135719806 0.047206740690402 0.04009120303153469 1.0748585679316296e-07 6.9686486773370016 -0.10935763359891015 KAAS(ph)LTEDRDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KAASLTEDRDR 11 2 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 KAAS(0.65)LT(0.35)EDRDR 83.87700000000001 0.034710000000000005 43721000.0 48985.0 52004.0 56642.0 68239.0 81559.0 67213.0 61055.0 54241.0 46866.0 44244.0 True False 57277.19300214904 57166.61343753716 57992.5600959812 64415.790063823035 65578.09942618026 63688.23195827581 55271.428400079065 52817.23122309 47551.32658823882 52265.08696468871 1.0958977843248707 1.093782039933465 1.1095850684255455 1.232482213362499 1.254720947283338 1.2185616758143882 1.0575210261760686 1.0105643038300947 0.9098105322270947 1.0 15.673559928653772 -7.589561006069009 2.5433764819973126 0.9646563512518211 1.1676901860012687 0.6856828330502647 0.059237238266121206 0.1870288161667397 2.433098637684658 0.038338407138825255 0.019710210305183825 2.5729953061044805e-08 7.589561006069009 0.20303383474944758 KAAS(ph)LTEDRDR ddPTM_PC-9_Lapatinib_30min_R1 1 KAASLTEDRDR 11 2 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 KAAS(0.928)LT(0.072)EDRDR 93.649 0.019644 16786000.0 73568.0 48123.0 63376.0 45883.0 54229.0 58983.0 55200.0 50199.0 57467.0 39450.0 True False 72518.90682928127 48011.574150168286 58165.46991843461 49257.38888120103 51039.35683831609 56460.434586088544 58057.985904325644 52531.428800459296 50994.461305662284 46268.879936179226 1.5673365538415864 1.0376644996894855 1.257118607553606 1.0645900430082593 1.1031033582121936 1.2202680217019948 1.2547955771656385 1.1353512095585259 1.1021330400909048 1.0 15.497754554526177 -4.7526839565541525 24.99978250208731 1.1425093700082658 1.5673373599211098 0.7018357476489578 0.08508645366323363 188.5151444894754 538236.3105902505 0.02057779429562781 0.23945738005447711 1.767323464037737e-05 4.7526839565541525 0.424827989912844 KAAS(ph)PSPQSVR ddPTM_PC-9_AZD4547_30min_R2 2 KAASPSPQSVR 11 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 KAAS(0.725)PS(0.089)PQS(0.186)VR;KAAS(0.944)PS(0.056)PQSVR 110.51 0.0028315000000000002 52554000.0 11932.5 7765.700000000001 12777.4 15904.5 16586.699999999997 12613.400000000001 11604.5 16015.6 9665.9 13275.0 True False 15726.786788581472 10275.810658459615 12607.963327395144 12237.963247075511 14283.92301228268 11824.68210403617 12637.278019104704 13540.757021875577 10176.819740674051 12810.246290595525 1.2276724765336546 0.8021555889993675 0.9842092838332949 0.9553261482614781 1.1150389062206427 0.92306438422789 0.9864976622957043 1.0570255024539494 0.794428109328798 1.0 13.645010592840643 -8.245366585837644 24.870869251721953 0.8972140156508611 0.9973087250681656 0.11824228449928642 0.11716306587018052 1462.6468419770154 2263294.0771298986 0.07454163719213543 0.02797204784611815 5.683729674766506e-09 8.245366585837644 0.10009470941730447 KAAS(ph)PSPQSVR ddPTM_PC-9_Lapatinib_30min_R1 1 KAASPSPQSVR 11 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 KAAS(0.714)PS(0.017)PQS(0.269)VR 94.67299999999999 0.009601 24260000.0 6858.2 5650.8 6938.4 6622.6 5269.3 4948.4 4605.5 5141.4 5522.9 4195.0 True False 6760.4008103601545 5637.71591978412 6367.951534998528 7109.648096345966 4959.370133842391 4736.768467283806 4843.950255115431 5380.288213603484 4900.852843284709 4920.100160513862 1.3740372329440727 1.1458538923718393 1.2942727438974435 1.4450210085973991 1.0079815394092357 0.9627382192945217 0.9845226920359123 1.0935322530185156 0.9960880232919602 1.0 12.264471970065179 -6.2801828155129495 24.768343264552133 1.00876903839718 1.3012629412254524 0.789345731991687 0.0776486789400136 344.010748183502 454588.7060233653 0.02474729769889707 0.028109855975450244 5.245865899454816e-07 6.2801828155129495 0.2924939028282725 KAAS(ph)TCTTHIIVVSMIFVPSIY(ph)LYAR ddPTM_PC-9_AZD4547_30min_R2 1 KAASTCTTHIIVVSMIFVPSIYLYAR 26 1 P58180 P58180 OR4D2 Olfactory receptor 4D2 2 KAAS(0.316)T(0.316)CT(0.316)T(0.051)HIIVVS(0.113)MIFVPS(0.11)IY(0.679)LY(0.098)AR 40.937 0.04374 5820300.0 8084.8 7924.7 9401.8 13905.0 13968.0 8781.4 2934.6 11247.0 7960.2 10211.0 True False 10655.598225713256 10486.204299045145 9277.125988973012 10699.417080108455 12028.78430523037 8232.297669810141 3195.7737149265113 9509.034580348822 8380.95992092961 9853.515997986508 1.081400611506659 1.0642093950208151 0.9415041281577787 1.0858476387814056 1.220760620644282 0.8354680371445431 0.32432826166614476 0.9650397464511066 0.8505552660230314 1.0 13.266422893266343 -6.925483275200132 7.135697609190484 0.7540461423412356 1.0687447990005092 0.36946405434546115 0.18411869370177006 0.23341357723521444 18.586750907576338 0.06586915835945911 0.05802342509310919 1.1871804188075277e-07 6.925483275200132 0.31469865665927366 KAAS(ph)TDLGAGETVVGK ddPTM_PC-9_AZD4547_30min_R2 2 KAASTDLGAGETVVGK 16 1 H7C207;Q15032-2;Q15032-4;Q15032;Q15032-3 H7C207 R3HDM1 R3H domain-containing protein 1 1 KAAS(0.5)T(0.5)DLGAGETVVGK;KAAS(0.913)T(0.086)DLGAGETVVGK 89.47 0.0017179000000000003 10050600.0 67626.0 77907.0 104911.0 145390.0 171180.0 134870.0 93645.0 140487.0 111415.0 128262.0 True False 89129.6612918173 103088.91419557961 103519.81159237037 111872.58175310817 147414.61178188273 126436.55757934904 101979.22358559686 118777.96222009983 117304.16944176944 123771.58641991447 0.7201140735922297 0.8328964439854099 0.8363778358723077 0.903863196627075 1.191021429439836 1.0215313646412614 0.8239308110636668 0.9596545189065203 0.9477471593827415 1.0 16.9173206352257 -5.811874995821154 3.040720803957524 0.9855490211151552 0.7928706757374643 0.4791454310412425 0.09025307175419894 0.245101558331722 4.606615409994363 0.028591360026077053 0.048039779800698464 1.542144268713427e-06 5.811874995821154 -0.1926783453776909 KAAS(ph)TDLGAGETVVGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KAASTDLGAGETVVGK 16 1 H7C207;Q15032-2;Q15032-4;Q15032;Q15032-3 H7C207 R3HDM1 R3H domain-containing protein 1 1 KAAS(0.5)T(0.5)DLGAGETVVGK;KAAS(0.844)T(0.156)DLGAGETVVGK 123.61 1.762e-05 10823100.0 86864.0 84621.0 88715.0 125049.0 116482.0 109557.0 93634.0 88614.0 95561.0 114477.0 True False 101568.35955779676 93021.61363929391 90830.30205351087 118042.90994432809 93658.18827303352 103811.63805592402 84764.30966854478 86287.9763942941 96958.39884134951 135230.77390056683 0.7510743052648539 0.6878731146483811 0.671668877087822 0.8728997589788496 0.6925804354406712 0.7676628260092275 0.6268122796581104 0.6380794393570532 0.7169847220769555 1.0 17.045063971483636 -8.61212755908889 20.173609627197507 1.0000000001831002 0.7125160950806282 0.616487396289771 0.06768306967824021 21097.56112671684 4768838.572974602 0.0674074997978202 0.01740454162873131 2.4427129842706423e-09 8.61212755908889 -0.287483905102472 KAAS(ph)TDLGAGETVVGK ddPTM_PC-9_Lapatinib_30min_R1 2 KAASTDLGAGETVVGK 16 1 H7C207;Q15032-2;Q15032-4;Q15032;Q15032-3 H7C207 R3HDM1 R3H domain-containing protein 1 1 KAAS(0.91)T(0.09)DLGAGETVVGK;KAAS(0.81)T(0.19)DLGAGETVVGK 71.89399999999999 0.0078937 15632800.0 169930.0 77969.0 113719.0 114125.0 109612.0 114794.0 96820.0 103326.0 146236.0 158524.0 True False 167506.76703865486 77788.46757090125 104369.46278803449 122518.13320983971 103164.83766548337 109884.52821788401 101832.86585610162 108126.90317010827 129765.3617466516 185924.66218004737 0.9009389344832757 0.4183870319235636 0.5613535157964373 0.6589665500706653 0.5548744123336349 0.5910164199275137 0.5477103718359203 0.5815629938614566 0.6979459326433428 1.0 17.504358625248123 -8.695299382935731 2.54598129432045 0.9998353911247398 0.5928803054105518 0.5141837899167626 0.11600703874630584 0.5294022496054824 6.20467591272544 0.10429667831660867 0.028123438521854286 2.0169754728365285e-09 8.695299382935731 -0.40695508571418804 KACEHFISDLSINS(ph)LY(ph)CLS(ph)DEK ddPTM_PC-9_Lapatinib_30min_R1 1 KACEHFISDLSINSLYCLSDEK 22 1 I3VM54;Q9Y2K7;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 3 KACEHFIS(0.032)DLS(0.087)INS(0.928)LY(0.977)CLS(0.977)DEK 42.172 0.036376 6115500.0 12369.0 10235.0 28616.0 11431.0 24102.0 27748.0 21037.0 18677.0 31377.0 17136.0 True False 12192.61579180321 10211.301486336522 26263.30294095439 12271.673872698148 22684.36774635518 26561.282723747256 22126.192925168456 19544.80160374067 27842.99184554207 20097.934767715276 0.6066601336267179 0.5080771534167606 1.3067662545677567 0.6105937756555464 1.1286914804199022 1.3215926427632012 1.1009187352280252 0.9724781092999096 1.3853658182963269 1.0 14.29475963948825 -4.805386764903932 0.6711467440020186 1.149460069313562 0.13091865750858095 0.4238756438933352 0.23041647666389237 2.9700681912659737 1.0339032000940682 0.10228388283259382 2.314300542780137 1.5653564067888793e-05 4.805386764903932 -1.018541411804981 KADGYNQPDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KADGYNQPDSK 11 1 O43390-4;O43390;O43390-2;B4DT28;O43390-3;O60506-2;O60506 O43390-4;O60506-2 HNRNPR;SYNCRIP Heterogeneous nuclear ribonucleoprotein R;Heterogeneous nuclear ribonucleoprotein Q 0 62.088 0.035792000000000004 2207500.0 14833.0 27384.0 19124.0 22166.0 22279.0 16007.0 21766.0 19549.0 18008.0 20254.0 False True 17343.933934895926 30102.502545448788 19579.98868817389 20924.11088314161 17913.589881139687 15167.564741286978 19704.166907806422 19035.859463877627 18271.33293221109 23925.889869424223 0.7249023559646314 1.2581560272045675 0.8183598936144849 0.8745384601089091 0.748711541301213 0.6339394197693006 0.8235500127828935 0.7956176162210064 0.763663672779866 1.0 14.54628496304156 -5.488446949687289 24.99269851673411 0.7928760700385035 1.0032114552180116 0.19346105380160084 0.1486724228691859 774.5764138756153 562233.6265344209 0.03635938483811362 0.07562270648526255 3.2475290924143566e-06 5.488446949687289 0.21033538517950812 KADGYNQPDSK ddPTM_PC-9_Lapatinib_30min_R1 2 KADGYNQPDSK 11 1 O43390-4;O43390;O43390-2;B4DT28;O43390-3;O60506-2;O60506 O43390-4;O60506-2 HNRNPR;SYNCRIP Heterogeneous nuclear ribonucleoprotein R;Heterogeneous nuclear ribonucleoprotein Q 0 ; 120.84 0.00052328 5536000.0 66335.0 53979.0 49453.0 52123.0 57719.0 51986.0 56404.0 59940.0 45519.0 60637.0 False True 65389.05073565078 53854.01494195985 45387.16523410043 55956.29929723081 54324.08189992007 49762.67996528491 59324.32313310843 62725.03122172813 40392.17088368005 71118.02465627629 0.9194441360215716 0.7572484641164332 0.6381949646867046 0.7868089639395316 0.7638581381088159 0.6997196590568304 0.8341671948824714 0.8819850034486656 0.567959685029235 1.0 16.117927632595485 -7.287248952174975 24.216817409538468 0.8111933875887652 0.7564515076192203 0.053357938871291366 0.12045605142677007 1967.313937262178 1845897.5611725382 0.04894387165484887 0.0330130275187314 5.161204269048265e-08 7.287248952174975 -0.05474187996954494 KADSLSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 KADSLSSPR 9 1 H7C1J4;Q6BDS2 H7C1J4 UHRF1BP1 UHRF1-binding protein 1 1 KADS(0.001)LS(0.232)S(0.767)PR 54.722 0.043051 3652800.0 41541.0 35442.0 42963.0 34985.0 42846.0 44295.0 34787.0 29946.0 41033.0 30065.0 True False 40948.61772231358 35359.93622655001 39430.747981975954 37557.91360653879 40325.882518477054 42400.60610668824 36588.100645901744 31337.40048324776 36411.43144335432 35261.69519090566 1.161277627199121 1.0027860553814125 1.118231774408439 1.0651193427656123 1.1436172396180628 1.20245512523243 1.0376160433528498 0.888709414382607 1.0326058133684166 1.0 15.105814212821423 -7.521840549080699 24.99756052067152 0.9690270882386708 1.1104286314851968 0.5225960112474448 0.06108128091822485 31.13189984353972 749652.2405667613 0.028066317165110138 0.016469142160227247 3.007180184100346e-08 7.521840549080699 0.14140154324652598 KADTTTPTPTAILAPGS(ph)PASPPGSLEPK ddPTM_PC-9_AZD4547_30min_R2 3 KADTTTPTPTAILAPGSPASPPGSLEPK 28 1 H0Y6K2;A0A140T9E9;A0A0G2JK44;P25440-4;P25440-3;P25440;P25440-2;H0YDJ7;U3KPW0;E9PIQ3;U3KQA6;A0A0G2JHL0;A0A140T9F7;A0A140T9V2 H0Y6K2 BRD2 Bromodomain-containing protein 2 1 KADTTTPTPTAILAPGS(0.629)PAS(0.37)PPGS(0.002)LEPK;KADTTTPTPTAILAPGS(0.617)PAS(0.383)PPGS(0.001)LEPK;KADTTTPTPTAILAPGS(1)PASPPGSLEPK 182.48 2.3086999999999997e-19 60532000.0 309368.0 297480.0 355286.0 431707.0 396449.0 397683.0 336911.0 379097.0 333115.0 388103.0 True False 407740.5887458517 393634.5924615377 350574.6755002517 332183.6209566614 341408.8995578667 372815.81914308807 366895.426316911 320516.2694324264 350722.77883224864 374515.6320993602 1.088714472237775 1.051049832699921 0.9360748803330139 0.8869686402529975 0.9116011997792652 0.9954613030523084 0.9796531703103182 0.8558154639253945 0.9364703333376502 1.0 18.51466641176318 -5.196987748184379 3.6087717449235575 0.9329055055262225 1.0802253544333635 0.5947713524165483 0.04391123779664725 0.16004114285466606 4.10758705158877 0.01195396563915742 0.036274121190748035 6.353488553289154e-06 5.196987748184379 0.147319848907141 KADTTTPTPTAILAPGS(ph)PASPPGSLEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KADTTTPTPTAILAPGSPASPPGSLEPK 28 1 H0Y6K2;A0A140T9E9;A0A0G2JK44;P25440-4;P25440-3;P25440;P25440-2;H0YDJ7;U3KPW0;E9PIQ3;U3KQA6;A0A0G2JHL0;A0A140T9F7;A0A140T9V2 H0Y6K2 BRD2 Bromodomain-containing protein 2 1 KADTTTPTPTAILAPGS(0.937)PAS(0.063)PPGSLEPK;KADTTTPTPTAILAPGS(0.951)PAS(0.049)PPGSLEPK 133.29 7.3305e-13 44837000.0 263450.0 277690.0 220459.0 288390.0 310190.0 238885.0 268150.0 250743.0 252650.0 222796.0 True False 308046.88162531727 305257.22801072436 225715.5786554134 272232.44327299536 249410.4962175459 226357.45006699188 242748.8907621193 244161.26193416963 256344.52828315922 263187.1511478345 1.1704480263638883 1.159848521021677 0.8576238531060623 1.034368289202994 0.94765453073904 0.8600626933335547 0.9223432439745706 0.9277096578207276 0.9740009235449655 1.0 18.005729532553346 -5.2473983258451575 24.535437335786057 0.9379795733175245 1.1651483440912946 0.7461419748488349 0.05240485409968593 289.0016187051559 505000.6613929125 0.013203890264312736 0.03453393694765111 5.657201842590476e-06 5.2473983258451575 0.22716877077377018 KADTTTPTPTAILAPGS(ph)PASPPGSLEPK ddPTM_PC-9_Lapatinib_30min_R1 1 KADTTTPTPTAILAPGSPASPPGSLEPK 28 1 H0Y6K2;A0A140T9E9;A0A0G2JK44;P25440-4;P25440-3;P25440;P25440-2;H0YDJ7;U3KPW0;E9PIQ3;U3KQA6;A0A0G2JHL0;A0A140T9F7;A0A140T9V2 H0Y6K2 BRD2 Bromodomain-containing protein 2 1 KADTTTPTPTAILAPGS(0.827)PAS(0.173)PPGSLEPK 149.44 5.2274999999999995e-11 19819000.0 209460.0 189120.0 186390.0 161150.0 206290.0 188830.0 177890.0 165830.0 187900.0 144120.0 True False 206473.06198974073 188682.1042594982 171065.733686207 173001.50858064054 194156.42778174454 180754.18108422926 187100.27377754494 173535.06719217845 166736.7233252816 169030.94997217128 1.2215103921721662 1.1162577284844122 1.0120379357411806 1.0234901277495214 1.1486442442269291 1.0693555299428186 1.1068994986323424 1.0266467012150657 0.9864271800681036 1.0 17.366927906052148 -4.879136920828999 3.079323285007633 1.0535882770580793 1.2309139505432234 0.5543555825635129 0.04810000972766516 0.24433722892677043 3.8575307483207926 0.012926954698215755 0.0944222158421093 1.3208791325137537e-05 4.879136920828999 0.17732567348514405 KADTTTPTPTAILAPGSPAS(ph)PPGSLEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KADTTTPTPTAILAPGSPASPPGSLEPK 28 1 H0Y6K2;A0A140T9E9;A0A0G2JK44;P25440-4;P25440-3;P25440;P25440-2;H0YDJ7;U3KPW0;E9PIQ3;U3KQA6;A0A0G2JHL0;A0A140T9F7;A0A140T9V2 H0Y6K2 BRD2 Bromodomain-containing protein 2 1 KADTTTPTPTAILAPGS(0.217)PAS(0.782)PPGS(0.001)LEPK;KADTTTPTPTAILAPGS(0.305)PAS(0.693)PPGS(0.002)LEPK 154.45 4.2835e-11 32854000.0 116297.0 134319.0 122989.0 122334.0 144894.0 128084.0 135021.0 131470.0 117157.0 90595.0 True False 135983.78512954843 147653.3026366539 125921.5241983798 115480.02259217904 116503.06083028195 121367.04956100462 122230.83341261267 128019.05180397966 118870.19948573138 107019.15635037434 1.270649010578495 1.3796904000368477 1.1766260218508942 1.0790593621772193 1.0886187557754414 1.1340684574606077 1.1421397587216648 1.1962255746518213 1.1107375869844969 1.0 16.707509535531067 -5.423707618754204 4.44696539275312 1.1176792922797723 1.3229075716202707 0.7118880087771491 0.05439890047357209 0.11545378531773572 3.8043684051267808 0.014225429567641432 0.030783115195176267 3.7695749368706393e-06 5.423707618754204 0.20522827934049848 KADVSEQVSNGPVES(ph)VTLENSPLVWK ddPTM_PC-9_AZD4547_30min_R2 1 KADVSEQVSNGPVESVTLENSPLVWK 26 1 F5GYK2;Q9NRL3;Q9NRL3-3;M0R2A7;M0QYS2;M0R0P4;Q9NRL3-2;M0QXN2;M0R0W8 F5GYK2 STRN4 Striatin-4 1 KADVSEQVSNGPVES(0.641)VT(0.162)LENS(0.197)PLVWK 97.352 0.00048364 0.0 20532.0 13764.0 18588.0 19862.0 20763.0 22857.0 21122.0 22319.0 19356.0 17326.0 True False 27060.748907869656 18212.943830309985 18341.51097481656 15283.122764841004 17880.415845468073 21427.748176697394 23001.81708126413 18870.111389597685 20379.118643942817 16719.422013623956 1.6185217937449623 1.0893285554649568 1.0970182438047698 0.9140939652332136 1.0694398305693864 1.2816081895197584 1.3757543210836423 1.128634194066112 1.218888944087704 1.0 14.029237354211583 -3.8386181843188996 0.014010934278355721 3.0353216255168264e-07 2.4693659626308 0.0822732265395586 0.1856428145202541 17600.515300669398 29.84553474144723 2300.574515325663 2997.2426033791185 0.00014500461203544035 3.8386181843188996 2.4693656590986377 KAEAGAGS(ph)ATEFQFR ddPTM_PC-9_AZD4547_30min_R2 2 KAEAGAGSATEFQFR 15 1 P46783;Q9NQ39 P46783 RPS10;RPS10P5 40S ribosomal protein S10;Putative 40S ribosomal protein S10-like 1 KAEAGAGS(0.656)AT(0.344)EFQFR;KAEAGAGS(0.868)AT(0.132)EFQFR 75.743 0.0067199 16178000.0 34524.0 32658.0 42956.0 57126.0 49447.0 47972.0 32958.0 44619.0 38668.0 51048.0 True False 45501.913856189945 43214.05983800226 42386.3753730482 43956.48328790189 42582.13756734862 44972.30325644339 35891.19815189392 37724.15879261884 40711.91153771344 49260.82505780192 0.9236937018979823 0.8772500214378367 0.8604479385660442 0.8923212966149877 0.8644219319790801 0.9129425502653185 0.7285951485745462 0.7658044449794308 0.826456144206734 1.0 15.588153170943594 -7.2289742975290086 24.951004136342814 0.810697585217719 0.8858033441443012 0.12020725497402118 0.06944628799488418 962.558941711141 739774.7723534461 0.02515018931111958 0.01947970756724577 5.9023601056048284e-08 7.2289742975290086 0.07510575892658222 KAEAGAGS(ph)ATEFQFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KAEAGAGSATEFQFR 15 1 P46783;Q9NQ39 P46783 RPS10;RPS10P5 40S ribosomal protein S10;Putative 40S ribosomal protein S10-like 1 KAEAGAGS(0.884)AT(0.116)EFQFR;KAEAGAGS(0.842)AT(0.158)EFQFR;KAEAGAGS(0.996)AT(0.004)EFQFR 89.913 0.00201 28482600.0 52219.0 49235.0 63975.0 79768.0 78490.0 79118.0 66694.0 83533.0 79300.0 50108.0 True False 61058.64532773752 54122.72541722068 65500.40662653855 75298.8575713453 63110.44794517943 74968.91280072111 60376.26149725443 81340.3472605295 80459.61247913931 59192.18374529021 1.031532230513388 0.9143559502740445 1.1065718897683052 1.2721081198045285 1.0661956351661208 1.2665339924494037 1.0200039545264865 1.3741737863658656 1.35929454512719 1.0 15.853119061883447 -5.484574728564433 4.686871432785695 1.1999832005063344 0.9767803127519062 0.320492345145165 0.12760324847143636 0.22425260192288496 11.506829357165056 0.033819259796208076 0.06975397018055829 3.2766139162606403e-06 5.484574728564433 -0.2232028877544282 KAEAGAGS(ph)ATEFQFR ddPTM_PC-9_Lapatinib_30min_R1 3 KAEAGAGSATEFQFR 15 1 P46783;Q9NQ39 P46783 RPS10;RPS10P5 40S ribosomal protein S10;Putative 40S ribosomal protein S10-like 1 KAEAGAGS(0.696)AT(0.304)EFQFR;KAEAGAGS(0.553)AT(0.447)EFQFR;KAEAGAGS(0.845)AT(0.155)EFQFR 70.907 0.010434 30579000.0 81836.0 55362.0 74678.0 59494.0 52870.0 66132.0 49169.0 47063.0 65704.0 46639.0 True False 80669.00363311579 55233.81269043113 68538.26310541638 63869.38722616604 49760.290546419295 63303.68852122153 51714.73023423527 49249.71879192845 58303.72362620694 54700.48900743888 1.4747400817960763 1.0097498887609526 1.2529734989406704 1.167620041156858 0.9096863931079711 1.1572782925690603 0.9454162325167227 0.9003524408206083 1.0658720732510827 1.0 15.73926610992475 -1.522878745280435 0.4362099796255954 0.9862602457448127 9.123104359155105 0.5282903700609087 0.11688223670055731 68.61144337684226 0.8514789575627731 0.07439666979537611 492.7447009578319 0.02999999999999326 1.522878745280435 8.136844113410293 KAEGEPQEES(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 6 KAEGEPQEESPLK 13 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 KAEGEPQEES(1)PLK;KAEGEPQEES(1)PLK;KAEGEPQEES(1)PLK;KAEGEPQEES(1)PLK;KAEGEPQEES(1)PLK;KAEGEPQEES(1)PLK 106.31 0.00051913 575368600.0 510213.0 623781.0 557231.0 456803.0 527962.0 561625.0 632025.0 602071.0 580557.0 514229.0 True False 672450.1209103317 825406.0095477024 549841.7528517331 351494.1258859965 454663.5895874886 526506.499966649 688274.0006053387 509034.761165217 611244.057789394 496225.99922912713 1.3551287557583918 1.6633671166564166 1.1080470465189178 0.7083347636601721 0.9162429826204098 1.0610215925496886 1.3870172092444826 1.025812355571832 1.2317856354542973 1.0 18.92063780010708 -5.344164158993356 6.263959294010172 1.0478021301076583 1.5068448371678003 0.4986149400033114 0.18268234574919678 0.1834910104844937 11.21914071680274 0.05137430235557926 0.10890886198680697 4.527264214744323e-06 5.344164158993356 0.45904270706014194 KAEGEPQEES(ph)PLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 KAEGEPQEESPLK 13 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 KAEGEPQEES(1)PLK;KAEGEPQEES(1)PLK;KAEGEPQEES(1)PLK;KAEGEPQEES(1)PLK;KAEGEPQEES(1)PLK;KAEGEPQEES(1)PLK;KAEGEPQEES(1)PLK 138.77 2.7941999999999998e-05 509486000.0 1414885.0 2107031.0 1351101.0 1539442.0 1598589.0 1133364.0 1656336.0 1168550.0 1098974.0 1126837.0 True False 1654397.0852474398 2316203.1127972375 1383316.3719190739 1453192.0556783031 1285356.9610171542 1073928.3966667056 1499435.8632458132 1137876.8006810714 1115044.4156954521 1331123.6280632152 1.242857575636748 1.7400360597364746 1.0392095390356786 1.0917032986580648 0.9656180191822967 0.8067833625861419 1.1264437289175704 0.8548242828028544 0.8376715672291398 1.0 20.34421313705105 -5.393031023430958 5.64392305396795 0.9583728400510308 1.4874995567262324 0.6691478181047542 0.14875124656448002 0.11813233870217497 4.872835788204804 0.03782189909315618 0.08032829461977717 4.04546992219138e-06 5.393031023430958 0.5291267166752015 KAEGEPQEES(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 8 KAEGEPQEESPLK 13 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 KAEGEPQEES(1)PLK;KAEGEPQEES(1)PLK;KAEGEPQEES(1)PLK;KAEGEPQEES(1)PLK;KAEGEPQEES(1)PLK;KAEGEPQEES(1)PLK;KAEGEPQEES(1)PLK;KAEGEPQEES(1)PLK 124.99 6.7837e-05 1035891300.0 730137.0 1101689.0 887394.0 1011080.0 1114658.0 950084.0 1148608.0 1205769.0 888852.0 1000640.0 True False 719725.1124892739 1099138.1068080722 814435.8907599006 1085438.1960640072 1049096.0079419464 909451.1220739763 1208077.3020578916 1261793.4296161463 788740.1277334924 1173599.290731011 0.6132630772475773 0.936553145088765 0.693964198165632 0.9248797307877632 0.8939132941095133 0.7749247373074823 1.0293780096828493 1.0751484255160046 0.6720693629954414 1.0 20.162508473550396 -3.380208714177356 0.4260063018481522 0.9313804394068101 1.0429534255970871e-13 0.2435203719075688 0.13383557635075816 25.841539104623358 1.4345825617623094 0.09106226050803379 15.691237802856616 0.00041666909161650897 3.380208714177356 -0.9313804394067059 KAEGEPQEES(ph)PLKSK ddPTM_PC-9_AZD4547_30min_R2 2 KAEGEPQEESPLKSK 15 2 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 KAEGEPQEES(0.999)PLKS(0.001)K;KAEGEPQEES(0.861)PLKS(0.139)K 96.14299999999999 0.0092188 96685000.0 49278.0 33534.0 43136.0 59744.0 50096.0 51519.0 44843.0 43384.0 41908.0 45843.0 True False 64947.378953925654 44373.20970688861 42563.9884554383 45970.9438355987 43141.0351199041 48297.50878572306 48833.940127598114 36679.99966514208 44123.17132312232 44238.05052352323 1.468133839202304 1.0030552698811515 0.9621578697914196 1.039172008973452 0.9752019948746206 1.0917639501325054 1.1038899668879183 0.8291504537623733 0.9974031586147807 1.0 15.433000190031317 -4.761469146126092 9.266192927539842 1.0000289549584145 1.4710142126466847 0.7912545061398975 0.07210518423136839 0.03568587581799207 47.20309179148645 0.018485025968273738 0.10536720446297203 1.73193206919011e-05 4.761469146126092 0.47098525768827026 KAEGEPQEES(ph)PLKSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KAEGEPQEESPLKSK 15 2 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 KAEGEPQEES(0.994)PLKS(0.006)K;KAEGEPQEES(0.993)PLKS(0.007)K 73.984 0.021764 174628000.0 201824.0 148229.0 139613.0 234412.0 216167.0 199872.0 226200.0 222009.0 201331.0 196288.0 True False 235988.81699429845 162944.1955086663 142941.90340525063 221278.65561395753 173810.6281177931 189390.36046545338 204772.69845381862 216181.4989879793 204275.08499416834 231873.4605850475 1.017748285633325 0.7027289587067727 0.6164651316480517 0.9543078153732736 0.7495925910591312 0.8167832575043146 0.8831226218694884 0.9323253227968596 0.8809765657473486 1.0 17.82297817810582 -7.8446099171366095 0.7163369272185832 0.9822275007350183 0.7921249634880974 0.21559353472118392 0.11114113629072313 0.9915794452643538 1.0046519182308304 0.10401344139524529 0.04896548754374993 1.4301779661770006e-08 7.8446099171366095 -0.19010253724692094 KAEGEPQEES(ph)PLKSK ddPTM_PC-9_Lapatinib_30min_R1 1 KAEGEPQEESPLKSK 15 2 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 KAEGEPQEES(0.999)PLKS(0.001)K 76.068 0.040279 48640000.0 171710.0 98755.0 94116.0 130360.0 112810.0 124480.0 81875.0 91680.0 107560.0 97279.0 True False 169261.3839122421 98526.33886498935 86378.14577826633 139947.10926821225 106174.73759299346 119156.28057705278 86114.0868825483 95939.78749429487 95445.46014298702 114093.54553388039 1.4835316329264172 0.8635575168073962 0.7570817908592044 1.226599704771683 0.9305937254922505 1.044373544703885 0.7547673839005774 0.8408870724926791 0.836554422919956 1.0 16.79985765265718 -7.245327453956965 23.710594351242648 0.8447928117862659 1.031593043954781 0.18185336565268362 0.19710648057611904 747.9131512231743 1100643.0517384268 0.07464815920663428 0.05759920884716232 5.6842418273756444e-08 7.245327453956965 0.18680023216851505 KAEPSEVDMNS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 6 KAEPSEVDMNSPK 13 1 Q9NR30 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 KAEPSEVDMNS(1)PK;KAEPSEVDMNS(1)PK;KAEPSEVDMNS(1)PK;KAEPSEVDMNS(1)PK;KAEPS(0.004)EVDMNS(0.996)PK;KAEPSEVDMNS(1)PK 106.17 0.00052606 196244200.0 662026.0 524850.0 490054.0 537339.0 514033.0 495742.0 573170.0 495810.0 539606.0 579643.0 True False 872536.4970037643 694497.4984988517 483555.56376440433 413463.7953547929 442668.39080544654 464743.1743716279 624181.0196225825 419193.9570803553 568128.4715325179 559349.8749995977 1.5599118476684952 1.2416155425070063 0.8644957036322787 0.7391863551504151 0.7913980329498866 0.8308631058011092 1.115904458945363 0.7494306798238881 1.0156942853217346 1.0 19.093391449864086 -5.008098055691466 2.4872437969064447 0.8759804504037051 1.5765171716107884 0.7692181640910571 0.11826121062791309 0.15572961097709473 1.6648925191271529 0.03182551492052923 0.18873649933551456 9.81526307446231e-06 5.008098055691466 0.7005367212070833 KAEPSEVDMNS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 KAEPSEVDMNSPK 13 1 Q9NR30 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 KAEPSEVDMNS(1)PK;KAEPSEVDMNS(1)PK;KAEPSEVDMNS(1)PK;KAEPSEVDMNS(1)PK;KAEPSEVDMNS(1)PK 82.87700000000001 0.0037305 132973000.0 651723.0 651983.0 428243.0 675925.0 636488.0 550368.0 704181.0 805371.0 542991.0 479348.0 True False 762046.8317840061 716707.5634344628 438453.9372406221 638055.1136284162 511772.74546733836 521505.73321250855 637475.8778510543 784230.8646111093 550931.2161369531 566249.9978833195 1.345778074406337 1.2657087260283686 0.7743115918403397 1.1268081519002366 0.9037929313560781 0.9209814307495487 1.1257852189562594 1.3849551744681976 0.9729469637022004 1.0 19.111079614202794 -5.02435972195233 23.784969818840786 1.037702883399013 1.3257609358486602 0.3426392006821447 0.1559579007273049 406.2995746018841 396717.15195548115 0.04132421508856762 0.11081337823717725 9.454537267046209e-06 5.02435972195233 0.2880580524496472 KAEPSEVDMNS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 7 KAEPSEVDMNSPK 13 1 Q9NR30 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 KAEPS(0.001)EVDMNS(0.999)PK;KAEPS(0.001)EVDMNS(0.999)PK;KAEPSEVDMNS(1)PK;KAEPSEVDMNS(1)PK;KAEPSEVDMNS(1)PK;KAEPSEVDMNS(1)PK;KAEPSEVDMNS(1)PK 135.86 5.0763e-05 223593200.0 1146804.0 981637.0 768345.0 999191.0 921081.0 802508.0 848820.0 751022.0 746817.0 820714.0 True False 1130450.3646619031 979364.0798380987 705174.6399974716 1072674.839343464 866904.8264949201 768186.6035775178 892767.7462918418 785917.2238606036 662702.6051283485 962573.3213673368 1.1744044215313352 1.0174436150452526 0.7325931691060895 1.1143824740745234 0.900611732375338 0.7980551574879591 0.927480251606874 0.8164751779575681 0.688469740868133 1.0 19.87653691263216 -1.522878856491629 0.765624318474449 0.8618613563496982 63.32200393131076 0.3672593312643513 0.12143535432221243 447.0253420315478 1.8058189236128936 0.04471335060131723 48248.77619995561 0.029999992317797135 1.522878856491629 62.46014257496106 KAIS(ph)SANLLVR ddPTM_PC-9_AZD4547_30min_R2 1 KAISSANLLVR 11 1 B7WPE2;Q32P44;G3V1D0;H0Y3M3;Q32P44-2 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 KAIS(0.935)S(0.065)ANLLVR 66.78399999999999 0.01895 36531000.0 48683.0 48897.0 56314.0 108870.0 74773.0 55573.0 59524.0 55930.0 42631.0 58429.0 True False 64163.18133069444 64701.999017049304 55567.23956508604 83771.70352473279 64392.05962592992 52098.01152485471 64821.52068673261 47287.30364354135 44884.38762708858 56383.418494403486 1.137979623159301 1.147535937777017 0.9855244866112817 1.4857507005015635 1.142038942394409 0.9239952616570395 1.14965573953567 0.8386739383004066 0.7960565149405356 1.0 15.782983329884402 -7.30003054115957 1.2127739953757632 0.8767626889361312 1.1749829816073973 0.376634349716677 0.14898291495606905 0.512499267681378 1.4589428141971346 0.10262405419705414 0.0568202757958796 5.011519895665924e-08 7.30003054115957 0.29822029267126615 KAIS(ph)SANLLVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KAISSANLLVR 11 1 B7WPE2;Q32P44;G3V1D0;H0Y3M3;Q32P44-2 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 KAIS(0.643)S(0.357)ANLLVR 56.793 0.036248 28318000.0 83476.0 40424.0 63951.0 87047.0 78630.0 79150.0 74867.0 86478.0 73454.0 56020.0 True False 97606.83807384702 44437.02756709102 65475.83437551808 82170.03880018168 63223.015950177825 74999.23466438832 67775.05576985874 84208.04413101498 74528.12578868453 66175.98254592401 1.4749586529540533 0.6714978132172522 0.98941990517602 1.2416897436038568 0.9553770645763072 1.133330126414689 1.0241639513674772 1.2724864957248998 1.1262110953466298 1.0 16.014020089800667 KALSSMGANYSS(ph)Y(ph)LAK ddPTM_PC-9_AZD4547_30min_R2 1 KALSSMGANYSSYLAK 16 1 A0A286YFB1;C9JCA5;H9KVA2;C9JZN9;F8WA37;P45378-5;P45378-7;P45378-4;P45378-6;P45378-2;P45378-3;P45378 A0A286YFB1 TNNT3 Troponin T, fast skeletal muscle 2 KALSSMGANY(0.019)S(0.184)S(0.815)Y(0.983)LAK 55.589 0.037636 0.0 17294.0 19071.0 19629.0 22400.0 21663.0 23721.0 22521.0 24741.0 22477.0 21017.0 True False 22793.132262453637 25235.327796268633 19368.706634639235 17236.026076550126 18655.46638059889 22237.722120113693 24525.325371042018 20917.846941620894 23665.08833229504 20281.20122707694 1.1238551408889468 1.2442718512440751 0.9550078625905325 0.8498523279547527 0.9198403078656124 1.09646967510113 1.2092639433160817 1.0313909273625264 1.1668484557364558 1.0 14.307855483223255 -6.970830191571476 24.85325824781485 1.111402508812475 1.0171961788147283 0.1086948107963589 0.11651287372365227 461.11993602565104 392882.0257802057 0.0455260303598618 0.04014967475523825 1.0694729596521578e-07 6.970830191571476 -0.0942063299977467 KALSSTLLQS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KALSSTLLQSK 11 1 A0A1B0GTH6 A0A1B0GTH6 1 KALSSTLLQS(1)K 74.92 0.025343 0.0 3553.1 3246.5 3354.9 4278.2 5069.6 4117.3 4889.4 4740.6 3655.8 3560.2 True False 4154.569653076165 3568.791064628959 3434.8935395291032 4038.506324111539 4076.2482724281044 3901.381539907595 4426.2406358094595 4616.164273080888 3709.259158905892 4205.636077472304 0.9878576216640144 0.8485734378553016 0.8167357984035468 0.9602605288993016 0.9692346644691223 0.9276555241680412 1.0524545049246734 1.0976138182301598 0.8819734020199038 1.0 12.038108300699145 -6.389342013824092 1.3140815136165072 1.0064460390454406 0.8858565663416351 0.2768730808465637 0.07098891559615766 0.526235833747332 1.859257981869179 0.029636686117120545 0.03742892812508671 4.079979548930239e-07 6.389342013824092 -0.12058947270380549 KALVVPEPEPDSDS(ph)NQER ddPTM_PC-9_AZD4547_30min_R2 1 KALVVPEPEPDSDSNQER 18 1 Q5VTR2;C9J0A5;C9JXC9 Q5VTR2 RNF20 E3 ubiquitin-protein ligase BRE1A 1 KALVVPEPEPDS(0.197)DS(0.803)NQER 130.49 1.8939e-05 6116300.0 18361.0 19384.0 27398.0 36570.0 31975.0 25449.0 23261.0 27197.0 24217.0 17618.0 True False 24199.416067474904 25649.49892522002 27034.68461846481 28139.35150086777 27535.823178675626 23857.670006946293 25331.183937472077 22994.328574886353 25497.061180014633 17001.199182501838 1.4233946563241078 1.5086876313771609 1.5901633954321144 1.6551392168753405 1.6196400549801422 1.4032933648293084 1.4899645410627103 1.3525121568220217 1.499721337672286 1.0 14.053348890243734 -9.88504454373673 0.39111476688787383 0.8756596124946464 1.5558386621191895 0.7646502869989693 0.08579121024707749 3.5051632080614112 0.5670418081129 0.6941240785402897 0.06440613094683756 1.3030331250361266e-10 9.88504454373673 0.6801790496245431 KALVVPEPEPDSDS(ph)NQER ddPTM_PC-9_Lapatinib_30min_R1 4 KALVVPEPEPDSDSNQER 18 1 Q5VTR2;C9J0A5;C9JXC9 Q5VTR2 RNF20 E3 ubiquitin-protein ligase BRE1A 1 KALVVPEPEPDS(0.46)DS(0.54)NQER;KALVVPEPEPDS(0.111)DS(0.889)NQER;KALVVPEPEPDS(0.08)DS(0.92)NQER;KALVVPEPEPDS(0.077)DS(0.923)NQER 179.17 5.4372e-09 49027700.0 223872.0 166036.0 205422.0 162000.0 164077.0 173647.0 139234.0 151182.0 181016.0 115413.0 True False 220679.54422690335 165651.55384322148 188532.9961118509 173914.02041615776 154426.3134477936 166220.52260092762 146442.85524280567 158206.4676370254 160628.0718970152 135361.98327184445 1.6302918950568088 1.2237671895701112 1.3928061007589132 1.2848069761721066 1.1408396191836423 1.2279705023759193 1.0818610344139814 1.1687658810325117 1.1866557213071371 1.0 17.046463085976384 -1.5228787452803376 0.3121839723070594 1.0923183400595438 5.196733595308843 0.7153356413627596 0.08896946931097383 30.885738474967106 0.4410153952464257 0.08308037017469451 71.76481347509325 0.029999999999999995 1.5228787452803376 4.104415255249299 KANLQIDQINTDLNLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KANLQIDQINTDLNLER 17 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 98.421 0.010069 0.0 9634.2 7776.8 8324.4 9562.3 15094.0 15688.0 12233.0 13645.0 11449.0 9711.0 False True 11265.079775876387 8548.829308919294 8522.885266462801 9026.555332394884 12136.43905318562 14865.293662854387 11074.201680749606 13286.833208072554 11616.419965619996 11471.52742776629 0.9820034731041827 0.745221537650449 0.7429599345099903 0.7868660376077324 1.057961908700139 1.295842576889425 0.9653641810544796 1.1582444702099917 1.0126306229720552 1.0 13.485769877769126 -6.299069230548655 5.452289387225558 1.096512735049558 0.8037249035908871 0.5930461474151953 0.10818845635023981 0.12650559727967994 10.272113406080958 0.032906760166854655 0.03824002466870691 5.022625178595908e-07 6.299069230548655 -0.29278783145867093 KANNSQEPS(ph)PQLASSVASTR ddPTM_PC-9_AZD4547_30min_R2 2 KANNSQEPSPQLASSVASTR 20 1 Q96HC4;Q96HC4-7;Q96HC4-4;H0Y8Y3 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 1 KANNSQEPS(0.991)PQLAS(0.003)S(0.002)VAS(0.002)T(0.002)R;KANNS(0.001)QEPS(0.999)PQLASSVASTR 83.73299999999999 0.00038480000000000003 20024700.0 54354.0 46809.0 74428.0 91773.0 79001.0 66037.0 54063.0 75900.0 60552.0 62765.0 True False 71637.44136656667 61939.093850114776 73441.03608960875 70616.15272871587 68033.07480652235 61907.69595067443 58874.502266091455 64171.3990084889 63752.65510064192 60567.61645417915 1.1827680460359886 1.0226437406030857 1.212546248128629 1.1659060874904772 1.1232582490346303 1.0221253464301188 0.9720458838037885 1.0595001547904084 1.052586494779307 1.0 15.88625901700244 -6.722170286316345 4.613946943530537 1.021330109700002 1.1418602040733168 0.5754638230017466 0.05180984314706234 0.15675746490907522 7.444651473655719 0.01798574831974066 0.017394840724814727 1.895962371003583e-07 6.722170286316345 0.12053009437331474 KANNSQEPS(ph)PQLASSVASTR ddPTM_PC-9_Lapatinib_30min_R1 2 KANNSQEPSPQLASSVASTR 20 1 Q96HC4;Q96HC4-7;Q96HC4-4;H0Y8Y3 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 1 KANNSQEPS(1)PQLASSVASTR;KANNSQEPS(1)PQLASSVASTR 107.23 5.3673e-05 17129700.0 91639.0 71900.0 82529.0 68562.0 70721.0 63613.0 60765.0 52157.0 74986.0 52691.0 True False 90332.2110554656 71733.51996752273 75743.78419115285 73604.27819612728 66561.32982283561 60892.4202791457 63911.114374571545 54580.404628489705 66540.28704241382 61798.56914365576 1.4617201062613776 1.1607634442275254 1.2256559535396412 1.1910353138602319 1.0770691092880877 0.9853370575230691 1.0341843712595513 0.883198517130925 1.076728603339271 1.0 15.915285814552082 -1.522878745292563 0.32495921747914386 0.9623641880231889 5.550852002486629 0.782876436640333 0.07116378252279543 25.48794059606411 0.36339676385455993 0.06547059299288382 69.86957654754157 0.0299999999991555 1.522878745292563 4.58848781446344 KAPAGPSLEETSVSS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 KAPAGPSLEETSVSSPK 17 1 A0A087WXZ7;K7EIX2;Q6AI08 A0A087WXZ7 HEATR6 HEAT repeat-containing protein 6 1 KAPAGPSLEETSVS(0.006)S(0.994)PK;KAPAGPSLEETSVS(0.045)S(0.955)PK 130.47 1.2875999999999998e-05 12847600.0 67362.0 74014.0 57044.0 69431.0 73808.0 79118.0 85433.0 73755.0 79928.0 77105.0 True False 88781.71478335827 97937.57807734402 56287.55928811256 53424.75564825674 63561.03321881754 74170.73895279109 93036.37149434909 62357.859471292475 84152.83090375403 74405.5774189353 1.193213168462885 1.3162666224053807 0.7564965052443512 0.7180208460375552 0.8542509234347 0.9968438056085236 1.250395127915135 0.8380804455046561 1.131001650990994 1.0 16.18312314890761 -5.247380469097557 24.954169641476806 0.9390306786915724 1.254739935558595 0.38497614103828104 0.15747191337868513 844.6026524508668 1499139.8364040696 0.042909829833991366 0.11232415825696576 5.6574344527350995e-06 5.247380469097557 0.31570925686702267 KAPAGPSLEETSVSS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KAPAGPSLEETSVSSPK 17 1 A0A087WXZ7;K7EIX2;Q6AI08 A0A087WXZ7 HEATR6 HEAT repeat-containing protein 6 1 KAPAGPSLEET(0.001)S(0.005)VS(0.17)S(0.825)PK 91.926 0.0009779 5242500.0 31983.0 37374.0 21256.0 33185.0 42283.0 23974.0 36782.0 28088.0 22936.0 27517.0 True False 37397.090206955865 41084.24372383881 21762.823653828902 31325.75203722162 33997.94968105522 22716.761236185044 33297.742681380834 27350.719761696 23271.39560935105 32505.614275547832 1.150480956610859 1.2639122391464603 0.6695096874449736 0.963702816740376 1.0459100816510332 0.6988565434763557 1.024368972052587 0.841415256141473 0.7159192689632334 1.0 14.988401297320495 -5.2449017060297365 24.842668067998105 0.8733321949459579 1.207196655216185 0.5011727797743969 0.1345448181674958 598.6149096414225 899227.4954972106 0.033095675416633545 0.08700650281124324 5.689816940298421e-06 5.2449017060297365 0.3338644602702271 KAPAGPSLEETSVSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 KAPAGPSLEETSVSSPK 17 1 A0A087WXZ7;K7EIX2;Q6AI08 A0A087WXZ7 HEATR6 HEAT repeat-containing protein 6 1 KAPAGPSLEETSVS(0.002)S(0.998)PK;KAPAGPSLEETSVS(0.003)S(0.996)PK 198.6 1.0665e-12 17817100.0 172916.0 189746.0 136254.0 160077.0 138283.0 121931.0 121098.0 124042.0 104187.0 103953.0 True False 170450.18613108902 189306.6547949598 125051.72207565028 171849.59658121748 130149.46581483842 116716.29536504357 127367.86190293518 129805.44415758394 92452.36292225176 121921.1375413342 1.3980363829307474 1.5526975765853586 1.025677127013802 1.4095143799241237 1.0674889394852851 0.9573097636615631 1.0446741596366291 1.0646672658674692 0.7582964265807328 1.0 16.895588742990803 -5.661379946029903 0.5112083811013586 0.9239823369549252 1.601091390325021 0.6135162525414489 0.14444133220616634 1.3085895744853804 0.4903857155051723 0.10132377276061338 0.48421104767306683 2.1808211680384884e-06 5.661379946029903 0.6771090533700959 KAPAGQEEPGT(ph)PPS(ph)SPLSAEQLDR ddPTM_PC-9_AZD4547_30min_R2 1 KAPAGQEEPGTPPSSPLSAEQLDR 24 1 P13051;Q68DM5;F5GYA2;P13051-2 P13051 UNG;DKFZp781L1143 Uracil-DNA glycosylase 2 KAPAGQEEPGT(1)PPS(0.805)S(0.151)PLS(0.044)AEQLDR 106.36 0.0007682 0.0 7836.3 9219.9 11649.0 17685.0 12226.0 9926.1 8317.1 12654.0 10914.0 12599.0 True False 10328.08039483436 12200.052370028692 11494.52664867861 13607.9964805263 10528.630936121594 9305.419397852555 9057.305787642363 10698.615059992353 11490.891758627406 12157.912844837147 0.8494945248123057 1.003466016390259 0.9454358486834981 1.11927077074787 0.8659899993108252 0.765379676315421 0.7449720937495077 0.879971356640833 0.9451368754882141 1.0 13.569607961386112 -6.490410571397464 24.696738338480714 0.8479273800457753 0.980447786647402 0.24241287359298946 0.09444191386657992 702.7060691762363 534509.8461979356 0.029568126686583138 0.03349709691002706 3.232878839466435e-07 6.490410571397464 0.13252040660162667 KAPAGQEEPGT(ph)PPS(ph)SPLSAEQLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KAPAGQEEPGTPPSSPLSAEQLDR 24 1 P13051;Q68DM5;F5GYA2;P13051-2 P13051 UNG;DKFZp781L1143 Uracil-DNA glycosylase 2 KAPAGQEEPGT(1)PPS(0.512)S(0.463)PLS(0.026)AEQLDR 79.458 0.00054735 4622200.0 6731.9 8797.3 9517.5 9451.0 10650.0 10297.0 10643.0 9071.9 9474.8 7698.9 True False 7871.477708914303 9670.637804669748 9744.433295319745 8921.491110555417 8563.208951664687 9757.00719316749 9634.817991352733 8833.772237472585 9613.351025439446 9094.649625541138 0.8655064277361805 1.0633326409311055 1.0714468062577995 0.9809603973638051 0.9415655692349082 1.0728293661546022 1.0593940820209942 0.971315289889133 1.0570336869758679 1.0 13.150802343294089 -6.771858681747529 24.990341288287098 1.0320266499745174 0.9935652923922624 0.12149303840382764 0.06160009302448754 598.4289425391662 1435304.1196020753 0.02204042151202534 0.01964331612184378 1.6909910860653085e-07 6.771858681747529 -0.038461357582254996 KAPAGQEEPGT(ph)PPS(ph)SPLSAEQLDR ddPTM_PC-9_Lapatinib_30min_R1 2 KAPAGQEEPGTPPSSPLSAEQLDR 24 1 P13051;Q68DM5;F5GYA2;P13051-2 P13051 UNG;DKFZp781L1143 Uracil-DNA glycosylase 2 KAPAGQEEPGT(1)PPS(0.665)S(0.312)PLS(0.023)AEQLDR;KAPAGQEEPGT(1)PPS(0.575)S(0.355)PLS(0.069)AEQLDR 101.51 1.0375999999999999e-05 16567700.0 60461.0 58507.0 57404.0 47124.0 45404.0 48741.0 43407.0 47665.0 47961.0 37379.0 True False 59598.81505281053 58371.53063615935 52684.46470584798 50589.65616105569 42733.42598769856 46656.46105082042 45654.40206791781 49879.6899096375 42559.12712828007 43839.910345613236 1.359464802344747 1.33147011880238 1.2017466342998524 1.1539634949576911 0.9747607978850396 1.064246269734651 1.041389038161802 1.1377689761774028 0.9707849946034088 1.0 15.419957227481296 -5.589902131845017 1.3867565811262652 1.0405363283701938 1.366345284241234 0.8566935025686023 0.050383238616734986 0.16645372875416148 0.6081342619440968 0.01606790350879035 0.04960175864345956 2.570975086098582e-06 5.589902131845017 0.3258089558710402 KAPAGQEEPGT(ph)PPSS(ph)PLSAEQLDR ddPTM_PC-9_AZD4547_30min_R2 3 KAPAGQEEPGTPPSSPLSAEQLDR 24 1 P13051;Q68DM5;F5GYA2;P13051-2 P13051 UNG;DKFZp781L1143 Uracil-DNA glycosylase 2 KAPAGQEEPGT(1)PPS(0.132)S(0.822)PLS(0.046)AEQLDR;KAPAGQEEPGT(0.999)PPS(0.121)S(0.871)PLS(0.009)AEQLDR;KAPAGQEEPGT(1)PPS(0.213)S(0.64)PLS(0.148)AEQLDR 94.016 2.3654e-05 22861200.0 58132.7 53451.7 80695.0 106793.0 94267.0 82255.0 65620.0 85480.0 68058.0 66655.0 True False 76617.689364724 70728.91672003627 79624.93157482367 82173.52378540249 81179.65421686372 77111.58184688479 71460.05287721584 72271.03013498876 71655.40693683925 64321.42873820307 1.1911689598278108 1.0996166924076352 1.2379223088919236 1.2775450638675934 1.2620934548465321 1.1988474659158983 1.1109836065375343 1.1235918037384034 1.114020760149568 1.0 15.973011832251421 -8.179339548484194 0.783229616740078 1.0110035477499477 1.2114598972694146 0.6132355536937831 0.05122914035157974 0.46360095644758703 0.6041242958616998 0.055228515986113676 0.02206368706813711 6.616989591732765e-09 8.179339548484194 0.2004563495194669 KAPAGQEEPGT(ph)PPSS(ph)PLSAEQLDR ddPTM_PC-9_Lapatinib_30min_R1 1 KAPAGQEEPGTPPSSPLSAEQLDR 24 1 P13051;Q68DM5;F5GYA2;P13051-2 P13051 UNG;DKFZp781L1143 Uracil-DNA glycosylase 2 KAPAGQEEPGT(1)PPS(0.282)S(0.715)PLS(0.003)AEQLDR 95.713 2.0646999999999997e-05 6698900.0 60743.0 46811.0 61427.0 51793.0 48632.0 46105.0 46036.0 43504.0 51468.0 38237.0 True False 59876.79368109807 46702.61200555927 56376.70917507706 55602.02999638311 45771.56137419069 44133.19662600435 48419.51882412201 45525.35465916016 45671.13185793286 44846.21450240011 1.3351582590743205 1.041394742538633 1.257111883368882 1.2398377569506422 1.0206337788385922 0.9841008235743599 1.079679062354988 1.0151437565978665 1.0183943586919382 1.0 15.452698591023866 -6.267251415337762 24.473761200757934 1.021638938290159 1.2085010423965719 0.6420269924927596 0.07253365277192236 233.61373523262856 983716.9995861866 0.021472024044803938 0.0250090842694708 5.404413680456534e-07 6.267251415337762 0.1868621041064129 KAPAGQEEPGT(ph)PPSSPLSAEQLDR ddPTM_PC-9_AZD4547_30min_R2 4 KAPAGQEEPGTPPSSPLSAEQLDR 24 1 P13051;Q68DM5;F5GYA2;P13051-2 P13051 UNG;DKFZp781L1143 Uracil-DNA glycosylase 1 KAPAGQEEPGT(0.999)PPS(0.001)SPLSAEQLDR;KAPAGQEEPGT(0.998)PPS(0.001)SPLSAEQLDR;KAPAGQEEPGT(0.998)PPS(0.001)SPLSAEQLDR;KAPAGQEEPGT(0.995)PPS(0.004)S(0.001)PLSAEQLDR 122.35 4.8263e-09 205916000.0 189025.0 159911.0 210458.0 312189.0 289050.0 243436.0 193269.0 253085.0 204259.0 230325.0 True False 249131.01803575188 211599.10351995775 207667.18940918587 240218.64932196907 248920.3968661823 228213.90843691237 210469.56658833605 213976.52856473537 215055.7137369869 222261.3918554739 1.120892008980804 0.9520281581677067 0.9343376628551937 1.0807934176807996 1.1199443807498672 1.0267816040012434 0.946946137749351 0.9627246854634754 0.967580162895891 1.0 17.76189783973352 -7.191565440674523 6.354997797056528 0.9663412520759982 1.036406464183311 0.24877945410110913 0.05933104380674815 0.3843251337566427 28.260891190168596 0.02477941637576354 0.019069639929776658 6.433311188045293e-08 7.191565440674523 0.07006521210731287 KAPAGQEEPGT(ph)PPSSPLSAEQLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 KAPAGQEEPGTPPSSPLSAEQLDR 24 1 P13051;Q68DM5;F5GYA2;P13051-2 P13051 UNG;DKFZp781L1143 Uracil-DNA glycosylase 1 KAPAGQEEPGT(0.899)PPS(0.074)S(0.027)PLSAEQLDR;KAPAGQEEPGT(0.699)PPS(0.223)S(0.073)PLS(0.006)AEQLDR;KAPAGQEEPGT(0.998)PPS(0.001)SPLSAEQLDR;KAPAGQEEPGT(0.899)PPS(0.072)S(0.026)PLS(0.003)AEQLDR 123.88 1.9131e-08 145848000.0 113929.0 108719.0 119105.0 134606.0 147741.0 136085.0 126708.0 135892.0 119878.0 96777.0 True False 133214.92949968032 119511.90382115995 121944.91490822815 127064.4622185401 118792.21161764224 128948.46303604898 114705.30095352062 132324.97898947535 121630.98896310561 114321.9040136895 1.1652616412313117 1.0453981225404447 1.066680230357481 1.1114620886940856 1.0391028092343304 1.1279418773554368 1.0033536612527483 1.1574770393399856 1.0639342478807987 1.0 16.802742324046797 -11.325306034040347 1.5139153271070016 0.9572982256192598 1.0850963532712905 0.21015560020708557 0.05035510679089477 60339.197183158576 20958.906443841497 9393.717682964254 0.012782190844182003 4.728179611847772e-12 11.325306034040347 0.1277981276520307 KAPAGQEEPGT(ph)PPSSPLSAEQLDR ddPTM_PC-9_Lapatinib_30min_R1 4 KAPAGQEEPGTPPSSPLSAEQLDR 24 1 P13051;Q68DM5;F5GYA2;P13051-2 P13051 UNG;DKFZp781L1143 Uracil-DNA glycosylase 1 KAPAGQEEPGT(0.996)PPS(0.001)S(0.002)PLSAEQLDR;KAPAGQEEPGT(0.712)PPS(0.216)S(0.067)PLS(0.005)AEQLDR;KAPAGQEEPGT(0.967)PPS(0.023)S(0.008)PLS(0.002)AEQLDR;KAPAGQEEPGT(0.986)PPS(0.01)S(0.004)PLS(0.001)AEQLDR 105.58 1.2655e-06 206640000.0 255156.0 182894.0 243602.0 205015.0 220166.0 200863.0 185260.0 188385.0 211551.0 162089.0 True False 251517.42865012004 182470.52017997368 223573.9838909137 220092.48700999146 207216.26874301018 192272.55772452237 194851.85631585837 197138.0548332541 187723.89864921014 190105.8676799839 1.3230387453032946 0.9598363396501615 1.1760498853579238 1.1577364217946484 1.0900045920298957 1.0113972812674346 1.0249649771140346 1.036990900065788 0.9874703024170539 1.0 17.536443536366313 -6.589419325030673 3.0579623721611355 1.0148533384158707 1.1412853724249135 0.38951881005099376 0.08317317084465918 0.29460165340807143 5.594022430518826 0.02767404876530881 0.028274566663757023 2.573834838107407e-07 6.589419325030673 0.1264320340090428 KAPAGQEEPGTPPSS(ph)PLSAEQLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KAPAGQEEPGTPPSSPLSAEQLDR 24 1 P13051;Q68DM5;F5GYA2;P13051-2 P13051 UNG;DKFZp781L1143 Uracil-DNA glycosylase 1 KAPAGQEEPGTPPS(0.278)S(0.683)PLS(0.039)AEQLDR 107.24 5.4596e-07 9659400.0 6904.6 9063.0 9404.4 13853.0 22518.0 26669.0 25972.0 32357.0 30708.0 23215.0 True False 8073.41240793383 9962.714744719631 9628.636562385616 13076.861322031977 18105.75954681554 25270.430691908674 23511.744139003407 31507.663035075388 31157.046406171605 27423.695730161126 0.2943954924009214 0.363288553182219 0.3511064539633092 0.47684533298149834 0.660223177976062 0.9214815880602027 0.8573514077150705 1.1489211135179944 1.1361359428993543 1.0 14.743135387292822 -6.598949462712448 0.8936302237163416 1.095281478346986 0.3023036828100746 0.9536424915294788 0.06815968357301762 0.10963383827485022 0.1919792076122871 0.03934672062023947 0.04351878553332685 2.5179699178185525e-07 6.598949462712448 -0.7929777955369114 down KAPAGQEEPGTPPSS(ph)PLSAEQLDR ddPTM_PC-9_Lapatinib_30min_R1 2 KAPAGQEEPGTPPSSPLSAEQLDR 24 1 P13051;Q68DM5;F5GYA2;P13051-2 P13051 UNG;DKFZp781L1143 Uracil-DNA glycosylase 1 KAPAGQEEPGTPPS(0.047)S(0.728)PLS(0.225)AEQLDR;KAPAGQEEPGTPPS(0.309)S(0.661)PLS(0.031)AEQLDR 116.6 8.130800000000001e-09 29215000.0 46338.0 38276.0 50395.0 47495.0 80417.0 91808.0 81049.0 68972.0 119543.0 108100.0 True False 45677.21162265152 38187.374273670444 46251.717630325584 50987.94073867539 75687.03016590507 87881.58585490094 85245.32064419727 72176.69091466507 106078.80849640304 126784.940965804 0.3602731623700596 0.30119802858898054 0.3648045049987478 0.40216085877602514 0.5969717664365134 0.6931547641655965 0.6723615596207861 0.5692844147329164 0.8366830294539023 1.0 16.952023872247366 -6.613515184515033 0.20650789091708133 1.0839604976762465 1.7625771287433052e-20 0.8888538981499086 0.07211999173944639 1.8746734958566322 0.17609203825113362 0.22678726092833723 0.6048153435893294 2.434920664779132e-07 6.613515184515033 -1.0839604976762465 down KAPAPPVLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 KAPAPPVLSPK 11 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 KAPAPPVLS(1)PK;KAPAPPVLS(1)PK 106.3 0.0011236 31216000.0 203109.0 192634.0 159150.0 210680.0 204587.0 199147.0 175380.0 180853.0 168324.0 196344.0 True False 267693.43707035336 254899.1733368156 157039.56701323745 162110.9809735527 176183.62647867764 186694.30660824923 190988.48024392172 152906.32443850135 177221.26299974346 189470.05632246195 1.412853525597532 1.345326951837703 0.8288358068885008 0.8556021152896771 0.9298758331439353 0.9853499293340123 1.0080140574765837 0.8070210533862289 0.9353523529761764 1.0 17.531610338619338 -5.2288585220449235 7.745395800776791 0.9155826756223069 1.3822068480031302 0.8799346689226625 0.06801483321215221 0.08157651163969398 16.734715725313364 0.01799179127080178 0.04696231474049813 5.903933783649497e-06 5.2288585220449235 0.4666241723808233 KAPAPPVLS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KAPAPPVLSPK 11 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 KAPAPPVLS(1)PK;KAPAPPVLS(1)PK 90.49799999999999 0.0039905 20184600.0 142864.0 136451.0 102284.0 129382.0 139756.0 148567.0 196571.0 172709.0 153429.0 146884.0 True False 167048.05350738013 149996.9535067572 104722.83847422991 122133.14600210362 112371.81504684065 140775.88498274403 177950.37182920205 168175.57175031156 155672.60886584912 173512.90646689554 0.9627413712838195 0.8644714480382188 0.6035449500940147 0.7038850797269387 0.64762799111016 0.8113280323017504 1.02557426679469 0.9692395521159558 0.8971817257614196 1.0 17.404683453685628 -7.110453701859456 4.776552727045439 0.9689302165879803 0.7491851575199885 0.5064137845379558 0.10113145312574039 0.2073238662361427 7.355199667247336 0.042854194640743276 0.03308577618753041 7.754366046892625e-08 7.110453701859456 -0.2197450590679918 KAPAPPVLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 KAPAPPVLSPK 11 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 KAPAPPVLS(1)PK;KAPAPPVLS(1)PK 81.992 0.0066199 22012000.0 261070.0 228460.0 167236.0 167715.0 223180.0 234210.0 287630.0 254450.0 222310.0 245350.0 True False 257347.09392562555 227931.01490654022 153486.5016296282 180049.32058083883 210052.99118876207 224193.38427017632 302522.0740156013 266272.6759153941 197271.10677191743 287758.42059167416 0.8943164665571961 0.7920915552631965 0.5333866557720087 0.6256960967836515 0.7299629694827413 0.7791027758951461 1.051305721631259 0.925334088809279 0.6855441671048189 1.0 18.134498620580942 -7.034631535510403 5.936363307335425 0.9110975562158143 0.7083765188208699 0.36108827974909596 0.12580077193852163 0.22957797228966645 23.693012399236363 0.05045349858178269 0.040122509070777176 9.233544881165604e-08 7.034631535510403 -0.2027210373949444 KAPAPVT(ph)PPAPVQNK ddPTM_PC-9_AZD4547_30min_R2 1 KAPAPVTPPAPVQNK 15 1 P0DP91;Q03468 P0DP91;Q03468 ERCC6 DNA excision repair protein ERCC-6 1 KAPAPVT(1)PPAPVQNK 83.792 0.005440100000000001 15570000.0 147310.0 140190.0 191180.0 242780.0 247320.0 165370.0 159550.0 207080.0 182830.0 207510.0 True False 194151.51576165418 185503.67593513196 188644.82828520692 186810.82191360876 212983.88705394955 155029.3877578178 173749.64091069496 175080.54422500523 192494.02054515717 200245.13806112864 0.9695691872548023 0.9263829211099419 0.9420694560265404 0.9329106500282728 1.06361577172941 0.774198011791388 0.8676846918383335 0.8743310620183875 0.9612918566162375 1.0 17.611407688954685 -6.75705102955133 24.999994786872307 0.8859082966333646 0.9613892527130593 0.2140009258438661 0.06676215597666567 169.51849880196013 965730.771819437 0.022131905859376074 0.02141049362336495 1.7496410939202988e-07 6.75705102955133 0.07548095607969474 KAPAPVT(ph)PPAPVQNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KAPAPVTPPAPVQNK 15 1 P0DP91;Q03468 P0DP91;Q03468 ERCC6 DNA excision repair protein ERCC-6 1 KAPAPVT(1)PPAPVQNK 105.06 0.00092217 8109500.0 114470.0 100720.0 105370.0 140980.0 177360.0 141970.0 143990.0 148500.0 134440.0 102840.0 True False 133847.5101144432 110718.81596470955 107882.42041795005 133081.34766332654 142607.5811894128 134524.8432760986 130350.22480267574 144602.0323487556 136405.93066450808 121484.07791900774 1.101769980125939 0.9113854083703439 0.8880375294108436 1.095463289864624 1.1738787801022608 1.1073454693032696 1.072981966324665 1.1902961674134809 1.122829699176287 1.0 16.890407716559814 -5.87535690784304 6.632736656815848 1.1198598498639731 0.9623285509071473 0.4446186954355248 0.07231257248258016 0.1740745125073022 9.435876375086007 0.020022900129151953 0.029958587850388428 1.33242598019847e-06 5.87535690784304 -0.15753129895682583 KAPAPVT(ph)PPAPVQNK ddPTM_PC-9_Lapatinib_30min_R1 1 KAPAPVTPPAPVQNK 15 1 P0DP91;Q03468 P0DP91;Q03468 ERCC6 DNA excision repair protein ERCC-6 1 KAPAPVT(1)PPAPVQNK 97.713 0.0020348 13163000.0 139880.0 128100.0 137020.0 110980.0 110880.0 112180.0 130430.0 108060.0 135620.0 95017.0 True False 137885.2855491499 127803.39232044043 125754.74451249528 119141.8394184272 104358.25639846739 107382.32290435232 137183.02720110872 113080.86209242478 120345.04745808776 111440.56184780593 1.2372989086097705 1.1468301146487503 1.1284467919700385 1.0691065931733086 0.9364476871624999 0.9635838255284827 1.2309972681980839 1.0147190593570319 1.0799034522317166 1.0 16.76591491111568 -5.276414460098778 1.4415417626715672 1.0434738435977575 1.229588800142069 0.395924955534388 0.07744639285033962 0.6434008520437596 2.1406600076193487 0.024782449024416647 0.13183766761467244 5.291582114827111e-06 5.276414460098778 0.18611495654431143 KAPDFVFYAPR ddPTM_PC-9_Lapatinib_30min_R1 2 KAPDFVFYAPR 11 1 P15311;E7EQR4;A0A2R8Y7M3;A0A2R8Y5S7;P35241;P35241-5;P35241-4;P26038 P15311;A0A2R8Y7M3;P26038 EZR;RDX;MSN Ezrin;Radixin;Moesin 0 ; 111.5 0.001142 15062100.0 73780.0 57908.0 63163.0 68979.0 60693.0 61463.0 60252.0 49203.0 67424.0 55258.0 False True 72727.8836704049 57773.91758385695 57969.9819562309 74051.94576719828 57123.15706702909 58834.37076725094 63371.55374469981 51489.15100438252 59829.999113804064 64809.27167334325 1.1221833202658664 0.8914452530041312 0.8944705049057753 1.1426134541434236 0.8814040891393701 0.9078079300719891 0.9778161690214644 0.7944719895002393 0.9231703669710083 1.0 15.9839126006887 KAPLNIPGT(ph)PVLEDFPQNDDEKER ddPTM_PC-9_AZD4547_30min_R2 1 KAPLNIPGTPVLEDFPQNDDEKER 24 2 C9J470;E9PHA2;Q15003;C9JZP1 C9J470 NCAPH Condensin complex subunit 2 1 KAPLNIPGT(1)PVLEDFPQNDDEKER 65.16 0.00063202 3499800.0 17483.0 20953.0 16622.0 28747.0 25033.0 24103.0 19354.0 27389.0 17872.0 24075.0 True False 23042.23033100941 27725.64749175275 16401.58141937814 22119.823286722614 21557.60005103321 22595.835599725993 21076.46850633398 23156.659386607425 18816.67743358886 23232.141577859686 0.991825495457928 1.193417636459972 0.7059866334065779 0.9521215774529751 0.927921344607235 0.972610963306969 0.9072116074920932 0.9967509585373655 0.8099415790200426 1.0 14.50383452987995 -5.237637715822653 24.987496583523082 0.9133660600876469 1.09262154851824 0.36446424053307414 0.09682084274163089 809.1829361062757 849494.6435879491 0.023174666987430703 0.061244159391415635 5.785784906287282e-06 5.237637715822653 0.17925548843059314 KAPLNIPGT(ph)PVLEDFPQNDDEKER ddPTM_PC-9_Lapatinib_30min_R1 1 KAPLNIPGTPVLEDFPQNDDEKER 24 2 C9J470;E9PHA2;Q15003;C9JZP1 C9J470 NCAPH Condensin complex subunit 2 1 KAPLNIPGT(1)PVLEDFPQNDDEKER 56.882 0.0031811 4461100.0 57777.0 50621.0 56091.0 50541.0 43682.0 46698.0 42609.0 42847.0 49994.0 40140.0 True False 56953.08938499582 50503.79018464494 51479.41449752143 54257.9537398335 41112.7106421163 44700.835398354844 44815.0855325618 44837.82804066376 44363.149259841 47078.14551681199 1.2097564328369181 1.072765072417936 1.0934885801552594 1.1525083060134038 0.8732865364765614 0.9495028937023828 0.9519297126212836 0.9524127925695758 0.9423300083899557 1.0 15.522769870987972 -6.253185207450469 24.999308736615486 0.943111560680416 1.125129210339868 0.807737359591603 0.04469013825216277 261.0065074144802 790506.9720290898 0.012959505766759409 0.016445417220074792 5.582320825949538e-07 6.253185207450469 0.182017649659452 KAPPPPIS(ph)PTQLSDVSSPR ddPTM_PC-9_AZD4547_30min_R2 2 KAPPPPISPTQLSDVSSPR 19 1 Q9P0K7-3;Q9P0K7;Q9P0K7-2 Q9P0K7-3 RAI14 Ankycorbin 1 KAPPPPIS(0.992)PT(0.008)QLSDVSSPR;KAPPPPIS(0.998)PT(0.002)QLSDVSSPR 144.33 2.0279e-05 116302000.0 225490.0 190521.0 271258.0 371006.0 305633.0 262148.0 260299.0 307248.0 264882.0 274183.0 True False 297191.1295166339 252103.18740878292 267660.94168317155 285476.29868556035 263201.13355959905 245755.84411886334 283465.1067340202 259769.88145665632 278883.12175267935 264583.9366248103 1.123239503152687 0.9528287719381637 1.0116295989001198 1.078963078134166 0.9947736696231408 0.9288388677478714 1.0713617400590125 0.9818051873081757 1.0540440410339267 1.0 18.013365950054926 -4.742567899454026 24.82837895429364 1.0090658482172319 1.1232399120161516 0.3569863319571226 0.046286708133850434 1345.2485398452543 1769784.1091960028 0.011324146621586133 0.39230265046845786 1.8089730655692385e-05 4.742567899454026 0.1141740637989197 KAPPPPIS(ph)PTQLSDVSSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 KAPPPPISPTQLSDVSSPR 19 1 Q9P0K7-3;Q9P0K7;Q9P0K7-2 Q9P0K7-3 RAI14 Ankycorbin 1 KAPPPPIS(0.483)PT(0.221)QLS(0.144)DVS(0.076)S(0.076)PR;KAPPPPIS(0.994)PT(0.003)QLS(0.003)DVSSPR;KAPPPPIS(0.972)PT(0.027)QLS(0.001)DVSSPR;KAPPPPIS(0.945)PT(0.035)QLS(0.018)DVSS(0.001)PR 167.36 3.4269e-08 101893700.0 226623.0 203943.0 225192.0 233910.0 246797.0 215553.0 200557.0 185868.0 179968.0 153373.0 True False 264985.79789172206 224189.11322766828 230561.4313254163 220804.78104645194 198438.8994970878 204249.0212206302 181558.78905306084 180989.1619434243 182599.69153399373 181178.3108000001 1.4625690940690783 1.2373948749039123 1.2725664032706954 1.2187153090868303 1.0952685154247928 1.1273370433732408 1.0021000209759146 0.9989560071746966 1.007845203588208 1.0 17.46705073239186 -4.723650500769058 0.35018481072011287 0.9676023280861797 1.7755272738918575 0.9083520972540922 0.04442984139247186 1.8823433644876248 0.17950539343082264 0.0423866238931434 0.6544938280667335 1.8895113248998132e-05 4.723650500769058 0.8079249458056778 KAPPPPIS(ph)PTQLSDVSSPR ddPTM_PC-9_Lapatinib_30min_R1 3 KAPPPPISPTQLSDVSSPR 19 1 Q9P0K7-3;Q9P0K7;Q9P0K7-2 Q9P0K7-3 RAI14 Ankycorbin 1 KAPPPPIS(0.882)PT(0.118)QLSDVSSPR;KAPPPPIS(0.953)PT(0.043)QLS(0.002)DVS(0.001)S(0.001)PR;KAPPPPIS(0.598)PT(0.117)QLS(0.07)DVS(0.092)S(0.123)PR 206.43 8.3709e-21 82986500.0 262407.0 210578.0 228963.0 182297.0 188386.0 150014.0 142271.0 140565.0 168256.0 137791.0 True False 258665.02806044972 210090.41957887402 210138.54596273883 195703.72950496507 177305.50586112612 143598.2509197141 149637.09624265082 147096.16305776162 149305.23746577182 161607.99075503333 1.6005707815063193 1.3000001955183684 1.3002979925743183 1.2109780499753526 1.097133285506205 0.8885591006287645 0.9259263452478158 0.9102035262645591 0.9238728652476713 1.0 17.302139008774333 -5.550171899489846 0.6313000185447052 0.9051725069892785 1.644300793603422 0.9064801784808947 0.06787229345722368 0.44467365957164817 0.2517928440346791 0.03875825453403708 0.21033360480424804 2.81726759883589e-06 5.550171899489846 0.7391282866141434 KAPPPPISPT(ph)QLSDVSSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KAPPPPISPTQLSDVSSPR 19 1 Q9P0K7-3;Q9P0K7;Q9P0K7-2 Q9P0K7-3 RAI14 Ankycorbin 1 KAPPPPIS(0.101)PT(0.532)QLS(0.061)DVS(0.109)S(0.198)PR 136.96 9.2434e-05 19213000.0 27621.0 22859.0 28952.0 24969.0 31053.0 21953.0 14576.0 18982.0 15724.0 14422.0 True False 32296.689760382968 25128.29045013195 29642.32548107145 23570.06788059022 24968.38756582569 20801.746033952197 13195.255758898576 18483.742613091472 15953.933753114563 17036.594435510815 1.8957245171643133 1.4749597136476365 1.739920827092382 1.3834964475917284 1.4655738657358637 1.2210037700136454 0.7745242635696362 1.0849435128046627 0.9364508742346082 1.0 14.056349353491523 -6.623743329357323 1.0357326262590714 0.9392944885457858 1.680604988945796 0.8144255067098599 0.14698137195220817 0.20819314276140213 0.48024070414484293 0.07453759872551889 0.07789358090363384 2.3782454286677306e-07 6.623743329357323 0.7413105004000101 KAPPPPISPTQLS(ph)DVSSPR ddPTM_PC-9_Lapatinib_30min_R1 1 KAPPPPISPTQLSDVSSPR 19 1 Q9P0K7-3;Q9P0K7;Q9P0K7-2 Q9P0K7-3 RAI14 Ankycorbin 1 KAPPPPISPT(0.02)QLS(0.7)DVS(0.14)S(0.14)PR 103.71 0.0015512 0.0 26914.0 28878.0 33279.0 22060.0 25165.0 21658.0 18392.0 19380.0 18648.0 17081.0 True False 26530.201424576866 28811.13476525904 30542.929080654936 23682.365990002712 23684.844176293584 20731.73782726388 19344.24776725285 20280.46555016836 16547.66586785444 20033.428090998157 1.3242966358063288 1.4381530027906242 1.5245982336083124 1.182142461211827 1.182266163769353 1.0348572262866735 0.9655984826653315 1.012331262430378 0.8260027087071526 1.0 14.290121693696026 -6.381384625615525 1.0828226965140284 0.9454691557021516 1.4322626118918376 0.8501048275144576 0.08208300200203762 0.17852518159501568 0.4410349363684775 0.03739530287444654 0.04980405612921589 4.155424293063295e-07 6.381384625615525 0.48679345618968595 KAPPPPISPTQLSDVS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 2 KAPPPPISPTQLSDVSSPR 19 1 Q9P0K7-3;Q9P0K7;Q9P0K7-2 Q9P0K7-3 RAI14 Ankycorbin 1 KAPPPPISPT(0.074)QLS(0.074)DVS(0.426)S(0.426)PR;KAPPPPIS(0.001)PT(0.177)QLS(0.177)DVS(0.323)S(0.323)PR 102.6 0.00023746 17156000.0 34222.0 33216.0 47225.0 51314.0 49607.0 43520.0 47176.0 37785.0 36623.0 32230.0 True False 45103.88413818019 43952.42242571755 46598.76564373315 39484.35009339704 42719.92432914968 40798.68752022884 51374.57260797826 31946.19646292167 38558.817012663654 31101.637510048484 1.4502093056549767 1.4131867626428727 1.4982737043564918 1.2695264061463074 1.3735586853054762 1.3117858346541202 1.6518285441202216 1.0271548066432297 1.2397680668809115 1.0 14.924702920208672 -7.781649018577946 24.999921658031983 1.1000959448102046 1.4142861585172852 0.6387860025925622 0.11521307343177617 162.697952873813 201259.31486034906 0.06067936030508132 0.02920511131205383 1.6532973948772025e-08 7.781649018577946 0.31419021370708067 KAPPPPISPTQLSDVSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 KAPPPPISPTQLSDVSSPR 19 1 Q9P0K7-3;Q9P0K7;Q9P0K7-2 Q9P0K7-3 RAI14 Ankycorbin 1 KAPPPPIS(0.03)PT(0.07)QLS(0.166)DVS(0.166)S(0.568)PR 54.047 0.015853 6484300.0 12384.0 13551.0 16964.0 35391.0 27827.0 20455.0 20486.0 30282.0 24600.0 26272.0 True False 16321.854396798059 17931.09574575199 16739.046275919307 27232.151735499356 23963.701378983787 19175.945616412697 22309.214313359396 25602.61271113388 25900.305778104645 25352.22527657445 0.6438036195536457 0.7072789686166283 0.6602594483643315 1.0741523254237555 0.9452306895176708 0.7563811620959104 0.8799706562237436 1.0098763493866074 1.0216186348752834 1.0 14.62982476403957 -3.908154811823839 0.38563005714285326 0.9849484791797981 1.1190682051409438e-13 0.5484200829935097 0.10441585542906652 9.716867245546522 0.6795875929739859 0.09176752868003228 5.059059251982173 0.00012355069369950804 3.908154811823839 -0.9849484791796862 KAPPPPISPTQLSDVSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 KAPPPPISPTQLSDVSSPR 19 1 Q9P0K7-3;Q9P0K7;Q9P0K7-2 Q9P0K7-3 RAI14 Ankycorbin 1 KAPPPPIS(0.003)PT(0.252)QLS(0.252)DVS(0.093)S(0.4)PR 92.39 0.00040387 7897000.0 37663.0 27016.0 39256.0 42818.0 36431.0 23883.0 16433.0 25655.0 24014.0 16711.0 True False 37125.91871345171 26953.446111858095 36028.52321254213 45966.97855666078 34288.20020610179 22861.579763992217 17283.820332713472 26847.024958182097 21309.29044136938 19599.47408399216 1.894230353036577 1.3752127223593351 1.8382392842861213 2.3453169385909307 1.7494449115911035 1.1664384292160357 0.8818512302240806 1.3697829259668433 1.0872378692433236 1.0 14.258527322328913 -6.749162117557876 4.6195615622799355 1.1040228033548163 1.8504408800636802 0.6946156153830295 0.24616781434940233 0.12293205745130333 6.488816253820521 0.09141826380371068 0.08654039034399878 1.781713548386305e-07 6.749162117557876 0.746418076708864 KAPSTSHSGFPPVANGPRS(ph)PPSLR ddPTM_PC-9_Lapatinib_30min_R1 1 KAPSTSHSGFPPVANGPRSPPSLR 24 2 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 KAPSTSHSGFPPVANGPRS(0.71)PPS(0.289)LR 70.538 0.0002295 10844000.0 23823.0 15463.0 36013.0 13168.0 22070.0 28245.0 15441.0 21652.0 35201.0 14049.0 True False 23483.279651396864 15427.19637354389 33052.15015420012 14136.418647160288 20771.885991289455 27037.027192310852 16240.459426606756 22658.03096451213 31236.292697036883 16477.350930884197 1.425185380216741 0.9362667845246921 2.005914075195733 0.8579303012029561 1.2606326149402953 1.6408600694201523 0.9856232045265586 1.3751015596835547 1.8957108353193701 1.0 14.008196698158214 -8.010254372771414 24.910837353478744 1.510372331055554 1.299984499997601 0.01797692384727012 0.3830467001196363 1558.5110691551092 3786053.0786649007 0.21626272980780334 0.09354021284738348 9.766650060980723e-09 8.010254372771414 -0.210387831057953 KAQCPIVER ddPTM_PC-9_AZD4547_30min_R2 1 KAQCPIVER 9 1 M0R0F0;M0R0R2;P46782 M0R0F0 RPS5 40S ribosomal protein S5;40S ribosomal protein S5, N-terminally processed 0 71.45100000000001 0.022112 4718000.0 18665.0 32272.0 20888.0 43194.0 31100.0 28781.0 23685.0 29293.0 26847.0 23517.0 False True 24600.081743882096 42703.29288664369 20611.011472023263 33236.29064064761 26782.30182507619 26981.319520213823 25792.91911607523 24766.439936174804 28266.077610763226 22693.6769880177 1.0840059879618 1.88172647866589 0.9082270573828081 1.4645617216723594 1.180165816197053 1.1889355583257841 1.1365685309478024 1.0913365846024654 1.2455486004179825 1.0 14.470002763024098 -5.852026589160238 0.2828172870608258 1.0318456186665825 1.5527411280119934 0.13094376515886585 0.24460614131453753 8.361788275583173 0.9036758218140163 0.3123692240002833 1.4621251509131505 1.4059614431870102e-06 5.852026589160238 0.5208955093454108 KAQCPIVER ddPTM_PC-9_Lapatinib_30min_R1 2 KAQCPIVER 9 1 M0R0F0;M0R0R2;P46782 M0R0F0 RPS5 40S ribosomal protein S5;40S ribosomal protein S5, N-terminally processed 0 ; 76.17 0.01576 15237800.0 136860.0 96464.0 87269.0 89465.0 95297.0 107635.0 73677.0 79509.0 87375.0 82329.0 False True 134908.35130294997 96240.64353473058 80094.07968808172 96044.55454649133 89691.81782111064 103031.70195943989 77491.63455567032 83203.2784018748 77533.90740046014 96559.45795350296 1.3971531547734397 0.9966982579901608 0.8294793838491725 0.9946674989905228 0.9288765670608947 1.0670285867703768 0.8025276466753312 0.8616792198848127 0.8029654375006502 1.0 16.559129956947395 -4.774477400708887 3.4948588174696282 0.9110364334309281 1.4603183271076239 0.7443575487098356 0.08508366626363165 0.14873329492319382 2.9664757516523257 0.02186515204992101 0.22036523616696993 1.6808253881922307e-05 4.774477400708887 0.5492818936766958 KAS(ph)DVHEVR ddPTM_PC-9_AZD4547_30min_R2 1 KASDVHEVR 9 1 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 1 KAS(1)DVHEVR 54.343 0.043778 21161000.0 23335.0 22290.0 25809.0 25573.0 25129.0 23408.0 27408.0 21686.0 25075.0 23292.0 True False 30755.044601847767 29494.806595292746 25466.755796698966 19677.539948911453 21640.27210811382 21944.294059593667 29847.258903668586 18334.92699470476 26400.41330837291 22476.554169533036 1.3683167077067455 1.3122477036659361 1.133036479017729 0.8754696027020171 0.9627931374573067 0.9763193189701272 1.3279285907679985 0.8157356708866768 1.1745756537787568 1.0 14.456133255696585 -5.348901243581872 3.0771947225622176 1.0194084352540873 1.350452713870679 0.45857440129507243 0.13779680305511605 0.21972268495836578 3.9715155997220726 0.036620431854843184 0.0934251068005926 4.478151235445078e-06 5.348901243581872 0.3310442786165917 KAS(ph)DVHEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KASDVHEVR 9 1 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 1 KAS(1)DVHEVR;KAS(1)DVHEVR 58.674 0.035480000000000005 23392000.0 41825.0 53500.0 46022.0 50525.0 56222.0 48357.0 48802.0 45480.0 45985.0 36746.0 True False 48905.146418595155 58811.12643081758 47119.33901940691 47694.24805426013 45205.70269300392 45821.07379236673 44179.12126411692 44286.19819004322 46657.44362992707 43407.758918824045 1.1266452734878956 1.3548528626137797 1.085504992495093 1.098749376659877 1.041419870985327 1.0555963941390243 1.0177701490356916 1.02023691830905 1.0748641439236748 1.0 15.405665319759224 -5.428736553703271 5.9827522147897545 1.0475076460173685 1.2400189189311572 0.6413751812798747 0.05790139772358146 0.12653717423516053 6.529191046020335 0.014332868030656457 0.03019419340230207 3.7261767039119236e-06 5.428736553703271 0.19251127291378878 KAS(ph)ERQY(ph)QRR ddPTM_PC-9_AZD4547_30min_R2 1 KASERQYQRR 10 3 Q8WVI0 Q8WVI0 SMIM4 Small integral membrane protein 4 2 KAS(1)ERQY(1)QRR 78.548 0.015475999999999998 5792800.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KAS(ph)ESTTPAPPTPR ddPTM_PC-9_Lapatinib_30min_R1 1 KASESTTPAPPTPR 14 1 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 KAS(0.419)ES(0.249)T(0.249)T(0.082)PAPPTPR 72.446 0.033446 2245700.0 2374.7 4459.0 3660.5 2705.9 4822.7 6320.7 8142.6 8174.7 5906.4 9264.6 True False 2340.836342533356 4448.675459460142 3359.547819938619 2904.9009126177866 4539.0382677930065 6050.3783952713475 8564.183985952213 8554.52640520956 5241.159034850675 10865.973765696473 0.2154281238855279 0.4094134180136221 0.30918055688157486 0.2673392164619856 0.41772954414105096 0.5568187928423125 0.7881653472226359 0.787276556125685 0.48234600486491547 1.0 13.407529848499477 -6.867849285614601 1.9364784175587142 0.7477991641196579 0.3104773925236937 0.7279214469075592 0.1277835620735601 0.17929180548649057 1.3782457614537598 0.052181880333790474 0.044361625457155225 1.3556597890012302e-07 6.867849285614601 -0.43732177159596414 KAS(ph)GPPVSELITK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KASGPPVSELITK 13 1 P10412;P16402;P16403 P10412;P16402;P16403 HIST1H1E;HIST1H1D;HIST1H1C Histone H1.4;Histone H1.3;Histone H1.2 1 KAS(0.998)GPPVS(0.002)ELITK 54.004 0.03823 20735000.0 58829.0 58151.0 71789.0 50401.0 81597.0 64787.0 58519.0 74726.0 59906.0 49119.0 True False 68787.58777428647 63923.84697342945 73500.72202129866 47577.195372246664 65608.65359896558 61389.455669004725 52975.6566791291 72764.52167874154 60782.01191898251 58023.88587420995 1.1855046717038422 1.1016815921637864 1.2667321554547546 0.8199587920634844 1.1307180243184447 1.0580031782444044 0.9129973954859743 1.2540442712935125 1.0475343214818793 1.0 15.824359295969986 -5.683386637676586 24.999999989403488 1.0426653619585895 1.1763427579862469 0.2625422101413567 0.11608463382694496 52.30205520251589 16749.381010740737 0.030834100884914856 0.053406219336524424 2.0730671142022215e-06 5.683386637676586 0.13367739602765738 KAS(ph)GSENEGDYNPGR ddPTM_PC-9_AZD4547_30min_R2 2 KASGSENEGDYNPGR 15 1 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 KAS(0.83)GS(0.17)ENEGDYNPGR;KAS(0.912)GS(0.088)ENEGDYNPGR 82.837 0.010851999999999999 15863600.0 9166.8 9273.599999999999 10862.8 14103.0 13370.1 14115.4 10133.7 12734.5 9632.0 11428.8 True False 12081.65171871515 12271.109844867951 10718.752174372574 10851.771239177962 11513.892399725122 13232.761806595545 11035.579668421855 10766.675634698322 10141.127855882267 11028.681190655987 1.0954756520617612 1.1126543267262643 0.9718979077438561 0.9839591018708645 1.0439953971541247 1.1998498803108895 1.0006255034166471 0.9762432559770022 0.9195231669652671 1.0 13.428972663365894 -7.5118085806873705 24.2001511453824 0.9664167555191355 1.0640199535233466 0.35175624471813505 0.06365935080670672 447.3073582981125 977853.6432637136 0.030330971555945337 0.0190490007914837 3.077452931722057e-08 7.5118085806873705 0.09760319800421102 KAS(ph)GSENEGDYNPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KASGSENEGDYNPGR 15 1 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 KAS(0.958)GS(0.042)ENEGDYNPGR;KAS(0.741)GS(0.258)ENEGDYNPGR 88.385 0.0022303 22223000.0 13676.7 13177.599999999999 18045.5 17781.5 28097.0 20647.6 23231.0 20470.3 16839.3 17783.9 True False 15991.895182861936 14485.785040275558 18475.77315793985 16785.260203400805 22591.59454600212 19564.803507977576 21030.391502124923 19932.976315075666 17085.542905674265 21007.980292725053 0.7612295403951725 0.6895372538640425 0.8794645130325978 0.798994475885597 1.07538155649477 0.9313034016293684 1.0010667950506233 0.9488287801744724 0.8132882203621875 1.0 14.358649847522686 -5.6959612395881365 1.529991610782542 0.9556664505821076 0.7287131342505194 0.5481499956143647 0.0781063033176316 0.30230972499665515 1.4134800536418888 0.02462585695815769 0.06059486899478061 2.0139039810533942e-06 5.6959612395881365 -0.22695331633158822 KAS(ph)GSENEGDYNPGR ddPTM_PC-9_Lapatinib_30min_R1 2 KASGSENEGDYNPGR 15 1 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 KAS(0.638)GS(0.358)ENEGDY(0.004)NPGR;KAS(0.818)GS(0.182)ENEGDYNPGR 110.57 0.00075298 11866100.0 12543.599999999999 12607.7 13717.9 13476.5 14034.900000000001 18355.8 14560.7 14512.8 21885.2 13767.3 True False 12364.725963785479 12578.50764526478 12590.06721462532 14467.606766286111 13209.394775675059 17570.76522345971 15314.581799947722 15187.117669581174 19420.258314627194 16146.959461225859 0.7657618756941353 0.7790016241429168 0.779717521732695 0.8959957322632522 0.8180731986969525 1.0881779486505108 0.9484498822656396 0.9405558802603313 1.2027192092270744 1.0 13.978974904642659 -6.46592667032841 0.7349748446361702 1.0526758440870208 0.7530029611681943 0.6503590138278367 0.08153277335500513 0.4475414183586862 0.5368245988519632 0.05102314558004615 0.07067621555939683 3.4203718986830976e-07 6.46592667032841 -0.29967288291882643 KAS(ph)GSENEGDYNPGRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KASGSENEGDYNPGRK 16 2 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 KAS(0.993)GS(0.007)ENEGDYNPGRK 83.25299999999999 0.022869 0.0 9306.8 12291.0 7673.8 11490.0 10709.0 11457.0 14284.0 16917.0 11766.0 15066.0 True False 10882.25742232114 13511.169251610832 7856.7724950485635 10846.2525510826 8610.648325199729 10856.174751104201 12930.916112795509 16472.946675043124 11938.055490914914 17797.34653760961 0.6114539265347559 0.7591676221541697 0.44145752168423075 0.6094308793820552 0.4838164108904427 0.6099883894581013 0.7265642709979102 0.9255844201399492 0.6707772681555221 1.0 14.119374540831453 -7.436174338414157 2.8538891539971116 0.848547500164993 0.5828056119050324 0.5559447057752602 0.1117160865132303 0.2131254042752771 3.3747574299680583 0.0538973222417927 0.032249748379100614 3.662905054872672e-08 7.436174338414157 -0.2657418882599606 KAS(ph)ISYFK ddPTM_PC-9_AZD4547_30min_R2 1 KASISYFK 8 1 D6RAY8;Q9H4L7;Q9H4L7-2 D6RAY8 SMARCAD1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 1 KAS(0.996)IS(0.004)YFK 60.691 0.031544 4410800.0 36730.0 37630.0 40000.0 54309.0 55746.0 62175.0 42089.0 47776.0 39225.0 45279.0 True False 48409.375968539454 49793.161605242974 39469.57386446428 41788.899115685774 48006.63014600312 58287.187421190894 45834.83946280306 40393.31698326177 41298.35342057536 43693.79599185498 1.107923330295301 1.139593401647341 0.9033221529166715 0.9564034931521102 1.0987058701640868 1.3339923002353993 1.0490010863635466 0.9244634407775315 0.9451765973428777 1.0 15.41514082798958 -7.642297988476414 5.631706850452193 0.9526089150754989 1.086704366079007 0.22907771527246035 0.10887381783288728 0.3482630975020697 15.713323601745701 0.058503336529741296 0.033040068709109936 2.2787779660340388e-08 7.642297988476414 0.13409545100350806 KAS(ph)PEAASTPR ddPTM_PC-9_AZD4547_30min_R2 3 KASPEAASTPR 11 1 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BVD2;H3BT57;H3BUJ5;P29590-14;P29590-10;H3BT29;P29590-2 P29590;P29590-2 PML Protein PML 1 KAS(0.998)PEAAS(0.001)T(0.001)PR;KAS(1)PEAASTPR;KAS(1)PEAASTPR 105.03 0.003833 24098900.0 36412.0 43343.0 42570.0 49388.0 41081.0 52157.0 42893.0 52577.0 43676.0 44324.0 True False 47990.258583350376 57352.77713143892 42005.49398525613 38002.35963699366 35377.612259677015 48895.61454486613 46710.39390524867 44452.43274926643 45984.6241936788 42772.23025117563 1.1219957037903425 1.3408881602535219 0.9820739703911412 0.8884820691796667 0.8271163802290771 1.1431626141010542 1.092072908776245 1.039282555251947 1.0751046630872112 1.0 15.384386814456551 -5.275668184549256 24.625965935884608 1.0047143470054707 1.2314419329931234 0.4425620538365175 0.10123831327069777 546.6822300356072 946150.2627843453 0.028535615873038163 0.05987938007109053 5.300682790402251e-06 5.275668184549256 0.22672758598765275 KAS(ph)PEAASTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KASPEAASTPR 11 1 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BVD2;H3BT57;H3BUJ5;P29590-14;P29590-10;H3BT29;P29590-2 P29590;P29590-2 PML Protein PML 1 KAS(0.998)PEAAS(0.002)TPR;KAS(0.992)PEAAS(0.007)T(0.001)PR 104.81 0.0038738 10227300.0 42807.0 52332.0 42689.0 53740.0 51244.0 37555.6 53842.0 43828.0 40648.0 33090.6 True False 50053.37962321108 57527.175109860684 43706.86765893406 50729.12202743077 41203.106058131976 35586.11822314469 48741.69597767677 42677.561439604564 41242.400101539126 39089.66383495452 1.2804760827452464 1.4716722904743706 1.1181182791306272 1.2977630670251017 1.0540665233679392 0.9103715594331382 1.2469203159043611 1.0917863509852366 1.0550717518491322 1.0 15.254499557276437 -5.734921746315593 1.2275358700492396 1.070198627517758 1.3691040978262552 0.49050684387687693 0.1138032495782316 0.4392402442641897 1.2919422461373107 0.039725300121313804 0.10778144895822288 1.8411037122681414e-06 5.734921746315593 0.29890547030849723 KAS(ph)PEAASTPRDPIDVDLPEEAER ddPTM_PC-9_AZD4547_30min_R2 1 KASPEAASTPRDPIDVDLPEEAER 24 2 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;H3BVD2;H3BT29;P29590-2 P29590;P29590-2 PML Protein PML 1 KAS(0.709)PEAAS(0.23)T(0.061)PRDPIDVDLPEEAER 53.964 0.027364999999999997 16983000.0 12795.0 10316.0 16873.0 20894.0 18973.0 12899.0 15770.0 16073.0 15948.0 14006.0 True False 16863.54384746699 13650.44525962494 16649.252995377654 16077.211109082067 16338.92644781899 12092.423490887672 17173.499449461957 13589.287170796348 16790.978721512707 13515.654203094618 1.2477045945438454 1.0099729583566484 1.2318495830979124 1.1895251881629925 1.2088890557793304 0.8946976083569025 1.2706376762384035 1.0054479765903503 1.2423356257271034 1.0 13.722343724401565 KAS(ph)PEPEGEAAGK ddPTM_PC-9_AZD4547_30min_R2 3 KASPEPEGEAAGK 13 1 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 KAS(1)PEPEGEAAGK;KAS(1)PEPEGEAAGK;KAS(1)PEPEGEAAGK 120.54 0.00030993 240710000.0 233396.0 190709.0 229500.0 277598.0 263693.0 240995.0 250750.0 258274.0 231197.0 230430.0 True False 307611.07306161895 252351.9547322424 226456.68004736377 213602.06994634643 227083.7786225022 225925.54455279247 273066.2642328845 218363.6878460937 243417.60142196974 222362.71583743297 1.3833752295349286 1.1348663096772673 1.0184111989931075 0.9606020017425432 1.0212313596157043 1.016022599391007 1.228021807543133 0.9820157440680707 1.0946871219180907 1.0 17.762555382166767 -4.7917416155898644 2.6669647481764005 1.0424218598971513 1.4469902199998865 0.6763149051384192 0.07165305946886678 0.2724452231818428 2.6211627177989487 0.01892616578905076 0.2471602344520324 1.6153193085978568e-05 4.7917416155898644 0.4045683601027352 KAS(ph)PEPEGEAAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 KASPEPEGEAAGK 13 1 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 KAS(1)PEPEGEAAGK;KAS(1)PEPEGEAAGK;KAS(1)PEPEGEAAGK;KAS(1)PEPEGEAAGK;KAS(1)PEPEGEAAGK;KAS(1)PEPEGEAAGK;KAS(1)PEPEGEAAGK 139.49 0.00010087 235736500.0 349703.0 386116.8 335396.0 420663.0 429715.0 381515.0 429293.0 396013.0 331731.9 332264.9 True False 408900.8109509141 424447.92414696695 343393.11263641383 397094.6159178474 345515.4304849376 361507.68178122723 388627.25922782946 385618.07836045616 336582.8514624034 392501.89616249857 1.0417804727792355 1.0813907609028275 0.8748826846284754 1.0117011403008545 0.8802898377384953 0.9210342301927644 0.9901283612320054 0.9824616954227593 0.8575317845676235 1.0 18.5823400980656 -5.247397793036691 24.795120741498202 0.9407037303684049 1.061585635472245 0.45173897796798135 0.05367905104352945 615.455918208792 1086788.3187414284 0.01303839544330373 0.03411095230649583 5.657208783058325e-06 5.247397793036691 0.12088190510384011 KAS(ph)PEPEGEAAGK ddPTM_PC-9_Lapatinib_30min_R1 5 KASPEPEGEAAGK 13 1 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 KAS(1)PEPEGEAAGK;KAS(1)PEPEGEAAGK;KAS(1)PEPEGEAAGK;KAS(1)PEPEGEAAGK;KAS(1)PEPEGEAAGK 174.39 6.6511e-05 420444000.0 251584.0 279625.0 262416.0 253276.0 279452.0 243736.0 236918.0 240795.0 246915.0 211915.0 True False 247996.3660251454 278977.5454926093 240841.16943505337 271902.76194396726 263015.1827837707 233311.97945636662 249184.45479132293 251983.2147653654 219104.83256978108 248544.22539101142 0.9977957268369276 1.122446297248387 0.9690073026486954 1.0939814092087958 1.0582228670571343 0.9387141426815234 1.002575917421957 1.0138365289676063 0.8815526984184964 1.0 17.9231430589222 -6.750690480147645 24.975857746086422 0.970403144004752 1.0505442268607226 0.358073952816911 0.054076291009271776 234.3620833853826 544556.6009221295 0.017078676781376624 0.016915251868379905 1.7754543889718817e-07 6.750690480147645 0.08014108285597055 KAS(ph)PEPPDSAEGALK ddPTM_PC-9_AZD4547_30min_R2 3 KASPEPPDSAEGALK 15 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 KAS(0.803)PEPPDS(0.197)AEGALK;KAS(0.999)PEPPDS(0.001)AEGALK;KAS(1)PEPPDSAEGALK 163.56 0.00048394 228823000.0 193661.0 190041.0 218304.0 255036.0 226390.0 226472.0 231933.0 243742.0 221450.0 237043.0 True False 255241.16960096144 251468.03679569458 215409.1463227004 196241.3904669214 194959.65627585206 212310.6700386318 252574.5876862432 206077.27453395448 233155.3949008645 228744.1967202735 1.1158366999495535 1.0993417118389657 0.9417032187536533 0.8579076246769264 0.8523042729440876 0.9281576235932318 1.1041792155064436 0.9009071158467993 1.01928441570907 1.0 17.80337561687574 -5.249418746958676 6.506786066372321 0.9447253150676114 1.109062107350086 0.4279147098587588 0.0724065194467244 0.14370321912533598 30.620958713719396 0.01985267448166099 0.04923617383363305 5.630944580315694e-06 5.249418746958676 0.16433679228247455 KAS(ph)PEPPDSAEGALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 KASPEPPDSAEGALK 15 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 KAS(0.992)PEPPDS(0.008)AEGALK;KAS(0.987)PEPPDS(0.013)AEGALK;KAS(0.999)PEPPDS(0.001)AEGALK;KAS(1)PEPPDSAEGALK 216.34 1.3804e-17 151345600.0 233102.0 225465.0 210866.0 260277.0 305150.0 207482.0 281081.0 226540.0 191022.0 202403.0 True False 272561.56462563964 247847.67515372476 215893.84515375845 245694.52351941986 245358.04803760312 196601.2786688137 254454.9728297862 220593.56503897093 193815.3353718808 239097.06167873307 1.1399620000009525 1.0365985822391646 0.9029548236098692 1.0275932367983325 1.026185961110985 0.8222655572948045 1.0642329564538482 0.9226109408879952 0.8106136228152572 1.0 17.86723687496913 -1.5228790822471578 0.7324701586578687 0.941281224706531 32.47338955989107 0.3479618300517747 0.08205664512445014 391.81835097206937 1.8204464610734543 0.030965897806465272 20337.15463857822 0.029999976723165712 1.5228790822471578 31.532108335184535 KAS(ph)PEPPDSAEGALK ddPTM_PC-9_Lapatinib_30min_R1 3 KASPEPPDSAEGALK 15 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 KAS(0.998)PEPPDS(0.002)AEGALK;KAS(0.889)PEPPDS(0.111)AEGALK;KAS(1)PEPPDSAEGALK 160.47 0.0004178 408830000.0 381762.0 518951.4 570851.7 546297.7 631375.3 620597.2 548049.8 621833.4 588080.7 468801.2 True False 376318.0038734237 517749.799917578 523918.4767772869 586474.2552537045 594239.0461856 594055.7044387311 576425.1370157332 650726.049878435 521844.85880169144 549832.8627816674 0.6844225388231395 0.9416494265152187 0.9528686119755072 1.0666409648318658 1.0807630580305378 1.0804296080691418 1.0483642867389418 1.1834979207796663 0.9490972514113081 1.0 19.068633611835637 -4.23157360279248 0.9366194683946608 1.0677242950960415 1.6437112747194351e-21 0.7609736959519788 0.062080025364964826 2.2275075678480927 0.753627009269302 0.019427826952505098 3.0927493750080464 5.867139268564716e-05 4.23157360279248 -1.0677242950960415 KAS(ph)PEPPDSAEGALKLGEEQQR ddPTM_PC-9_AZD4547_30min_R2 1 KASPEPPDSAEGALKLGEEQQR 22 2 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 KAS(0.947)PEPPDS(0.053)AEGALKLGEEQQR 40.641999999999996 0.035717 13979000.0 30819.0 9873.7 29119.0 108190.0 80176.0 30546.0 15745.0 32021.0 16759.0 43244.0 True False 40618.800924977375 13065.180434272854 28732.86303398339 83248.4670188375 69044.94633849857 28635.953791197353 17146.274497893366 27072.89021937846 17644.8465258234 41730.04072244917 0.9733707473505054 0.313088130471061 0.6885414568629022 1.9949289667012713 1.6545621605721323 0.68621916718601 0.4108856402018636 0.6487626120339316 0.42283319690917875 1.0 15.348798708011932 -6.974913805442779 24.851604254818177 0.5852363665468332 1.1105409043354582 0.21881814079763107 0.4630085209873882 361.83680823892036 358451.92918668315 0.1837268041210245 0.1620260959245065 1.059463976448233e-07 6.974913805442779 0.525304537788625 KAS(ph)PPSGLWSPAYASH ddPTM_PC-9_AZD4547_30min_R2 1 KASPPSGLWSPAYASH 16 1 Q8TEM1 Q8TEM1 NUP210 Nuclear pore membrane glycoprotein 210 1 KAS(0.746)PPS(0.253)GLWSPAYASH 82.94200000000001 0.01487 0.0 10771.0 11834.0 16022.0 19746.0 17896.0 11977.0 12743.0 18356.0 13344.0 15924.0 True False 14195.953949282286 15659.109073517013 15809.53781141118 15193.864772658877 15411.44930744577 11228.076296640176 13877.102313537962 15519.501978917311 14049.336597684069 15366.50560688837 0.9238244733349553 1.0190416399221875 1.0288310313259648 0.9887651207993506 1.002924783402757 0.7306850746604971 0.9030746917059171 1.0099564843135422 0.9142831140077904 1.0 13.907501508353114 KAS(ph)PPSGLWSPAYASH ddPTM_PC-9_Lapatinib_30min_R1 1 KASPPSGLWSPAYASH 16 1 Q8TEM1 Q8TEM1 NUP210 Nuclear pore membrane glycoprotein 210 1 KAS(0.987)PPS(0.012)GLWSPAYASH 88.28299999999999 0.0018503 5245100.0 80510.0 61202.0 59656.0 54787.0 56241.0 53334.0 47360.0 45889.0 53428.0 37467.0 True False 79361.91263627438 61060.290529239675 54751.31395881935 58816.21874407433 52933.01495406027 51053.02914762637 49812.069065740296 48021.170466030715 47410.37601821789 43943.12102836061 1.806014474598987 1.3895301266797082 1.2459587001907124 1.3384624798524145 1.2045802327034905 1.161797977769423 1.1335578333999512 1.0928029084469935 1.0789032483063625 1.0 15.423349719320523 -1.5228787452803376 0.45730670922276434 1.0904249267130068 16.92070001294619 0.9108378648743995 0.06515475292887828 25.90170499756485 0.30685322527523856 0.04131200769885184 384.62232070296756 0.029999999999999995 1.5228787452803376 15.830275086233184 KAS(ph)SEGGTAAGAGLDSLHK ddPTM_PC-9_AZD4547_30min_R2 3 KASSEGGTAAGAGLDSLHK 19 1 C9JEY1;C9K057;A0A1W2PNV4;O15143 C9JEY1 ARPC1B Actin-related protein 2/3 complex subunit 1B 1 KAS(0.932)S(0.067)EGGT(0.001)AAGAGLDSLHK;KAS(0.499)S(0.167)EGGT(0.335)AAGAGLDSLHK;KAS(0.766)S(0.227)EGGT(0.007)AAGAGLDSLHK 131.75 1.8749e-05 29294300.0 47642.0 46182.0 94304.0 161801.0 124053.0 149477.0 66773.0 136182.0 87540.0 92511.0 True False 62791.16498483959 61109.42836176803 93053.46734286094 124500.2792505306 106830.38226064891 140130.17956023093 72715.66764355903 115138.20105104167 92167.18568354804 89272.21804815691 0.7033673673366958 0.6845290696015105 1.0423563946026777 1.3946139344646988 1.196681169084658 1.5696952828554036 0.8145386015202778 1.2897428065350818 1.0324285393450119 1.0 16.44592365097448 -5.374014405288108 3.585051227617861 1.199645178046789 0.6903654119591652 0.4797200390620938 0.20075988862827632 0.1861395535043843 4.312793515916589 0.05253303528777834 0.12263125622620463 4.2265459483307786e-06 5.374014405288108 -0.5092797660876237 KAS(ph)SEGGTAAGAGLDSLHK ddPTM_PC-9_Lapatinib_30min_R1 2 KASSEGGTAAGAGLDSLHK 19 1 C9JEY1;C9K057;A0A1W2PNV4;O15143 C9JEY1 ARPC1B Actin-related protein 2/3 complex subunit 1B 1 KAS(0.744)S(0.252)EGGT(0.004)AAGAGLDSLHK;KAS(0.424)S(0.424)EGGT(0.151)AAGAGLDSLHK 105.32 0.00011118 13100900.0 54002.0 40898.0 73221.0 32032.0 45997.0 75448.0 58299.0 58398.0 75382.0 53108.0 True False 53231.92157724606 40803.30319376561 67201.05202123373 34387.74013561953 43291.546893581406 72221.26491787817 61317.43696080217 61111.384272380354 66891.68535234901 62287.64703803817 0.854614423703276 0.655078577118953 1.0788824946332458 0.552079614030362 0.6950262042671781 1.159479742006849 0.9844237160436723 0.9811156333303216 1.0739157526932943 1.0 15.926658454130312 -6.75448928071279 24.999695658489454 1.0351464989484018 0.7662824585279523 0.4910082212156228 0.1387577986826428 144.06292055516585 518197.7633626359 0.04582681286511094 0.044872291409320454 1.7599921035153237e-07 6.75448928071279 -0.26886404042044953 KAS(ph)SPSPLTIGTPESQR ddPTM_PC-9_AZD4547_30min_R2 2 KASSPSPLTIGTPESQR 17 1 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 KAS(0.499)S(0.499)PS(0.002)PLTIGTPESQR;KAS(0.662)S(0.261)PS(0.073)PLT(0.004)IGT(0.001)PESQR 70.89699999999999 0.006464 18056600.0 27141.0 27405.0 37162.0 51377.0 54740.0 38249.0 30086.0 33788.0 40724.0 41307.0 True False 35771.27343212984 36263.130316016024 36669.207598780566 39532.826416737305 47140.295881179125 35857.28398348417 32763.595715695155 28566.840970999016 42876.5875003062 39860.854502872266 0.8974035774760488 0.9097429236847645 0.9199302939212776 0.9917706709947394 1.18262130777408 0.8995613473589833 0.8219491559904794 0.7166640386231702 1.0756565064910144 1.0 15.282685017319055 -6.977665802758143 24.999651722085765 0.8772129932202437 0.9804016291573323 0.08060649436994216 0.1182567971333038 476.88241321096865 533793.8890927165 0.042621582671175835 0.03758635224125116 1.0527716885295832e-07 6.977665802758143 0.1031886359370886 KAS(ph)SPSPLTIGTPESQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KASSPSPLTIGTPESQR 17 1 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 KAS(0.847)S(0.115)PS(0.037)PLT(0.001)IGTPESQR 63.125 0.012163 6025400.0 32266.0 34513.0 25643.0 27557.0 31325.0 24573.0 26193.0 28828.0 21524.0 18849.0 True False 37727.99651745111 37939.22255152911 26254.42637161906 26013.07063099943 25187.091118394026 23284.348621705787 23711.809419101963 28071.295545790817 21838.74778059259 22266.174491398106 1.6944085537471303 1.703894962566912 1.1791170675394511 1.1682774982765374 1.1311817900342214 1.0457273938413185 1.0649251593830065 1.2607147921451596 0.9808037653270596 1.0 14.442566092306059 -5.2956209679311605 3.76148162298766 1.1065108796403103 1.7129343536914683 0.9018838409303446 0.0788120897490379 0.057983558167068884 1.7708329598203973 0.02051441768621662 0.05139004293413099 5.062663149926171e-06 5.2956209679311605 0.606423474051158 KAS(ph)VVDPSTESSPAPQEGSEQPASPASPLSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KASVVDPSTESSPAPQEGSEQPASPASPLSSR 32 1 Q66K14;Q66K14-2 Q66K14 TBC1D9B TBC1 domain family member 9B 1 KAS(0.595)VVDPS(0.046)T(0.046)ES(0.192)S(0.12)PAPQEGSEQPASPASPLSSR 131.03 8.147300000000001e-14 0.0 13896.0 11701.0 9938.8 9175.9 9545.9 5363.7 5065.1 6215.4 4212.8 3431.3 True False 16248.318341489496 12862.597950784984 10175.7786851089 8661.804071669183 7675.449420816517 5082.4181297457935 4585.297059851619 6052.252335760656 4274.40423016542 4053.3675278441456 4.00859735266381 3.173311539707869 2.5104505365495604 2.136940213826629 1.8935981916495095 1.2538754738702331 1.1312315077163482 1.493141762789927 1.0545316211280837 1.0 11.984905278344106 -3.915337758894884 0.39060293035409194 1.009431163517098 9.10971602012981 0.976742923691263 0.14589478750276771 1.583130647494863 0.1132114416382567 0.12260931651539375 6.867068615973298 0.00012152405178844205 3.915337758894884 8.100284856612712 up KAS(ph)VVDPSTESSPAPQEGSEQPASPASPLSSR ddPTM_PC-9_Lapatinib_30min_R1 1 KASVVDPSTESSPAPQEGSEQPASPASPLSSR 32 1 Q66K14;Q66K14-2 Q66K14 TBC1D9B TBC1 domain family member 9B 1 KAS(0.637)VVDPS(0.057)T(0.057)ES(0.125)S(0.125)PAPQEGSEQPASPASPLSSR 92.42399999999999 2.6660000000000004e-10 9935100.0 39131.0 30574.0 36389.0 29964.0 27370.0 22962.0 17513.0 17099.0 23120.0 32311.0 True False 38572.98476425348 30503.207781460944 33397.2368856021 32167.652516973783 25760.150411490373 21979.968787036367 18419.737448232874 17893.481962968446 20515.98213560675 37895.91329829877 1.0178666090093968 0.8049207718350543 0.8812886134374117 0.8488422554634105 0.6797606435479892 0.5800089475089414 0.4860613149296965 0.47217444852481555 0.5413771657675752 1.0 15.209754655856845 -6.357394242965364 2.0506205391948384 0.5742262230361289 0.8925922642111679 0.41738419147922623 0.14976046362904397 0.28024666665312586 2.3184354085725 0.05002447638128355 0.060590334894426695 4.391427902899366e-07 6.357394242965364 0.31836604117503897 KASDVHEVR ddPTM_PC-9_AZD4547_30min_R2 4 KASDVHEVR 9 1 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ;;; 84.81700000000001 0.0051244 36292900.0 265527.0 196374.0 322163.0 242695.0 278280.0 304892.0 224910.0 281711.0 487157.0 582540.0 False True 349959.0626952998 259848.05519712938 317890.9081224355 186745.41735037207 239645.6254624509 285827.05504176527 244926.55429159754 238179.03802477472 512907.12446927367 562145.4519113757 0.6225418377136885 0.4622434537424584 0.5654958286001612 0.33220124207251106 0.42630537105231603 0.5084574714069321 0.4356996102322128 0.42369646007973844 0.9124099869976985 1.0 19.10058394225149 -8.315167547091509 4.78656986521688 0.9829383742144077 0.468255978850356 0.8611271758436345 0.07789769602173328 0.07186235644405667 3.4619444409372835 0.07292463372914064 0.019673817208373412 4.839856140577567e-09 8.315167547091509 -0.5146823953640516 KASDVHEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 KASDVHEVR 9 1 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ;;;; 84.81700000000001 0.0051244 39593800.0 91946.0 218464.0 215414.0 202483.0 462407.0 375352.0 155182.0 282942.0 404475.0 416337.0 False True 107510.64178372135 240151.66214172237 220550.28672214466 191138.53396874297 371801.6677664243 355667.88035056816 140482.03753961305 275515.07230182935 410389.6816834781 491815.6023781212 0.21859949392387157 0.48829614388094833 0.44844101255775043 0.38863861383110504 0.7559777810395146 0.7231732353157861 0.2856396520572494 0.5601999427622995 0.8344381099320215 1.0 18.9077579782128 -12.374303794372858 0.08584460746788179 2.1648171717341853 1.4379638706299195e-13 0.5609194724563612 0.15843121248872963 114.05785329779805 1.0904141143087618 30.442508433812286 5.513227726469781 4.2237305571673724e-13 12.374303794372858 -2.1648171717340414 KASDVHEVR ddPTM_PC-9_Lapatinib_30min_R1 4 KASDVHEVR 9 1 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ;;; 84.81700000000001 0.0051244 40805200.0 220971.0 241654.0 212510.0 229232.0 326544.0 221304.0 370276.0 530589.0 412634.0 290508.0 False True 217819.91301888163 241094.46501017731 195038.24811232262 246090.48597553506 307337.32393020496 211839.34380482094 389447.0795056177 555242.1019503752 366158.813691347 340721.92072242295 0.6392894022111765 0.7075989255372581 0.5724264752287983 0.7222619708581016 0.9020180541321393 0.6217367622126103 1.1430056471854941 1.6296048718353997 1.0746558745471702 1.0 18.37823524224148 -7.363080239460784 4.511528906306228 1.2833865246475589 0.700519550226338 0.6682650126496976 0.17782118235581387 0.12400812215401964 4.203100137235156 0.07458547440740666 0.04914817695737441 4.334307911025281e-08 7.363080239460784 -0.5828669744212208 KASESTTPAPPT(ph)PRPR ddPTM_PC-9_Lapatinib_30min_R1 1 KASESTTPAPPTPRPR 16 2 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 KASESTTPAPPT(1)PRPR 59.983000000000004 0.022336 3135200.0 19353.0 11563.0 14074.0 14190.0 12673.0 14933.0 8819.1 8740.6 14257.0 11793.0 True False 19077.022671094466 11536.226583928608 12916.890047211082 15233.579936452345 11927.599056076633 14294.3504005232 9275.709845812287 9146.720185129081 12651.226527134319 13831.404336815242 1.3792542106745365 0.834060396399697 0.9338813133262265 1.1013762280020194 0.8623563280793387 1.0334706478412845 0.6706267577705759 0.6613009035375481 0.9146740431454508 1.0 13.755660023883243 -7.246874191744013 24.38016760454932 0.7834255005079664 1.0074941799148225 0.2589734979211197 0.172054047217804 740.8052629214473 1240009.9559485954 0.06376300125868778 0.0491506656688201 5.6640334338292376e-08 7.246874191744013 0.22406867940685604 KASGPPVSELITK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KASGPPVSELITK 13 1 P10412;P16402;P16403 P10412;P16402;P16403 HIST1H1E;HIST1H1D;HIST1H1C Histone H1.4;Histone H1.3;Histone H1.2 0 87.083 0.0046035 3998900.0 45748.0 48289.0 51851.0 73841.0 75432.0 71778.0 70488.0 65040.0 63842.0 53407.0 False True 53492.232835813345 53082.812789116855 53087.32448601255 69703.92816575206 60651.64109314281 68013.83532205263 63810.866351073244 63332.76891557634 64775.56847280211 63089.26633042064 0.8478816753971387 0.8413921396882874 0.841463652596237 1.1048460731923575 0.9613622826978027 1.078057160561042 1.0114377621206327 1.003859651559116 1.0267288279047295 1.0 15.945106953234287 -5.745686099974046 24.9999894851939 1.0255663335527718 0.8433603560100699 0.8289398673920031 0.038100443283347316 85.47428228362995 135644.06756153674 0.009589588919573882 0.0165373937388412 1.7960312960413037e-06 5.745686099974046 -0.18220597754270196 KASGS(ph)ENEGDYNPGR ddPTM_PC-9_Lapatinib_30min_R1 1 KASGSENEGDYNPGR 15 1 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 KAS(0.057)GS(0.943)ENEGDYNPGR 91.065 0.0018442 10401000.0 6798.8 7579.5 8586.8 7801.3 7623.7 9754.9 7777.2 8844.1 8640.5 7021.0 True False 6701.847865252777 7561.950133433088 7880.826450006538 8375.033626373897 7175.288954770889 9337.705666782555 8179.865361868138 9255.029172974402 7667.315901501302 8234.570495105561 0.8138673254708549 0.9183174930529451 0.9570415912634083 1.0170577362051638 0.8713616525641156 1.1339638991897236 0.9933566500803 1.1239237284416204 0.9311130320711417 1.0 13.007477687407778 -3.3761275405827624 0.5235874274479502 1.0290432427647842 8.77928474005401e-18 0.4156385871494158 0.07345533057260413 15.411738710986683 1.0212276797218507 0.03786301445320422 13.40638016626941 0.00042060309045530126 3.3761275405827624 -1.0290432427647842 KASPEPPDS(ph)AEGALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KASPEPPDSAEGALK 15 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 KAS(0.008)PEPPDS(0.992)AEGALK;KAS(0.009)PEPPDS(0.991)AEGALK;KAS(0.382)PEPPDS(0.618)AEGALK 168.68 0.00013486 53437200.0 90985.0 90015.0 79476.0 108152.0 103773.0 95486.0 101682.0 93575.0 80800.0 76373.0 True False 106386.96346433675 98951.09431158986 81371.0092544083 102092.5940735147 83439.42559071368 90478.54606650387 92049.94484607036 91118.75540090806 81981.54714141811 90218.82033166479 1.1792103141366093 1.0967899374855852 0.9019294306362029 1.1316108290731273 0.9248560919326088 1.002878842062934 1.0202964803538102 1.0099750258974227 0.908696731347577 1.0 16.461140801576747 -5.028838066641733 5.299229717259426 0.9924010411705636 1.1632842580266678 0.4895594679609664 0.06383065679961501 0.12735588215821808 10.403524479303767 0.015317353792062753 0.04866576233587852 9.357545195314247e-06 5.028838066641733 0.1708832168561042 KASPEPPDS(ph)AEGALK ddPTM_PC-9_Lapatinib_30min_R1 1 KASPEPPDSAEGALK 15 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 KAS(0.463)PEPPDS(0.537)AEGALK 122.13 2.5177e-05 360590000.0 290670.0 349070.0 384830.0 331720.0 367880.0 382170.0 346110.0 343710.0 316070.0 302000.0 True False 286524.99249765003 348261.7498617973 353190.7628867588 356115.79538548144 346242.02167990827 365825.4799817824 364029.8822707639 359680.0213750437 280470.86823534704 354200.297610295 0.8089349287134028 0.9832339278409317 0.9971498196632038 1.0054079507784432 0.977531707386811 1.03282092773473 1.0277514861697936 1.015470692152771 0.7918425538533342 1.0 18.43420589872516 -4.761511009835851 7.570159158017924 0.9861053325263105 0.8061694030278751 0.3799298544926206 0.06578621252175083 0.10298509854207136 43.4303404484626 0.01604930924867402 0.09507601494928851 1.7317651280705585e-05 4.761511009835851 -0.1799359294984354 KASS(ph)PSPLTIGTPESQR ddPTM_PC-9_AZD4547_30min_R2 2 KASSPSPLTIGTPESQR 17 1 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 KAS(0.288)S(0.698)PS(0.013)PLT(0.001)IGTPESQR;KAS(0.066)S(0.826)PS(0.086)PLT(0.022)IGTPESQR 155.24 3.592e-14 11679000.0 36600.2 32281.5 42740.0 71343.0 65867.0 50476.6 38231.6 53930.0 44980.5 51295.6 True False 48238.30226854722 42715.86357586107 42173.23967418008 54895.97358836228 56722.50399717985 47320.290222508746 41634.13833557702 45596.357688113414 47358.07740048925 49499.75665716548 0.9745159476771759 0.8629509811878562 0.8519888282738692 1.1090150193781942 1.1459148049966992 0.9559701586059971 0.8410978386001854 0.9211430675086557 0.9567335396917309 1.0 15.59513381241112 -5.712045076641131 24.99999653326838 0.9855739686229611 0.8931317964605237 0.1908403400917319 0.08781513830106627 219.51699326806653 111102.51782143294 0.027179940301447034 0.04707693852631101 1.9406844380635236e-06 5.712045076641131 -0.09244217216243744 KASS(ph)PSPLTIGTPESQR ddPTM_PC-9_Lapatinib_30min_R1 1 KASSPSPLTIGTPESQR 17 1 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 KAS(0.188)S(0.809)PS(0.003)PLTIGTPESQR 63.54600000000001 0.011517 12386000.0 52746.0 27493.0 44707.0 34729.0 33951.0 39847.0 24632.0 32513.0 41722.0 25637.0 True False 51993.83236756825 27429.341647664885 41031.36303401064 37283.08651254783 31954.068930234185 38142.8366978938 25907.324434698367 34023.672674541966 37022.82900786264 30068.321290844793 1.7291897297704923 0.9122338883619876 1.3646043833682153 1.2399457273293069 1.0627154280130553 1.2685389493129946 0.861615258933216 1.1315454675848997 1.231290189091313 1.0 14.875956704296144 -4.748246124399175 24.99989766592119 1.1295760435363842 1.729191172079141 0.5845056712811514 0.1540717828851945 470.4961430642633 891490.9888696696 0.037390651445182846 0.6969420745801279 1.7854754192077895e-05 4.748246124399175 0.5996151285427569 KASSPS(ph)PLTIGTPESQR ddPTM_PC-9_AZD4547_30min_R2 2 KASSPSPLTIGTPESQR 17 1 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 KAS(0.178)S(0.119)PS(0.657)PLT(0.032)IGT(0.014)PESQR;KAS(0.015)S(0.179)PS(0.781)PLT(0.025)IGTPESQR 110.33 0.00018314 83467000.0 33598.0 35769.0 52047.0 73310.0 72628.0 56536.0 41122.0 60604.0 43636.0 64021.0 True False 44281.46511818649 47330.629749081454 51356.82277309434 56409.51212820939 62544.85585053481 53000.7949826208 44781.778336130315 51239.044341376335 45942.5098753404 61779.64427647578 0.716764650181837 0.7661201404344089 0.8312903606770976 0.9130760267211313 1.0123861440612147 0.8579006176440909 0.7248630007599793 0.8293839328707003 0.7436512529877777 1.0 15.914843943586515 -5.196015067509533 2.5497359198995606 0.8614274624938244 0.7244016722221303 0.24577210538191208 0.08871458105518261 0.4916042040948258 5.991408323078943 0.02577828456405126 0.09565745860100283 6.367734281654577e-06 5.196015067509533 -0.13702579027169415 KASSPS(ph)PLTIGTPESQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KASSPSPLTIGTPESQR 17 1 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 KAS(0.17)S(0.089)PS(0.542)PLT(0.199)IGT(0.001)PESQR;KAS(0.045)S(0.206)PS(0.389)PLT(0.226)IGT(0.131)PES(0.003)QR 95.926 0.00073453 86477000.0 63390.0 42992.0 65566.0 85225.0 101693.0 90467.0 83567.0 81316.0 77295.0 68806.0 True False 74120.67499043021 47259.961635770276 67129.3421004397 80450.11955317807 81766.9866593085 85722.75126194849 75650.92878731336 79181.54116142385 78425.29314722677 81279.98313200388 0.9119179425769997 0.5814464990601325 0.8259025102332681 0.9897900621180241 1.0059916784986742 1.054660052312379 0.9307448878828065 0.9741825491379345 0.9648783147488981 1.0 16.310612482257746 -5.641487301902851 3.926887512198156 0.9887113695651149 0.7377173756671953 0.6089820856958768 0.08038287781960764 0.12854307849626 3.650226585024806 0.021053764821413214 0.03826595647484412 2.283035676125969e-06 5.641487301902851 -0.25099399389791954 KASSPS(ph)PLTIGTPESQR ddPTM_PC-9_Lapatinib_30min_R1 2 KASSPSPLTIGTPESQR 17 1 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 KAS(0.023)S(0.227)PS(0.722)PLT(0.014)IGT(0.014)PESQR;KAS(0.039)S(0.434)PS(0.476)PLT(0.045)IGT(0.006)PESQR 82.76100000000001 0.0019465999999999997 91141000.0 267430.0 161497.0 238946.0 140465.0 142158.0 161936.0 110490.0 118115.0 159401.0 110468.0 True False 263616.39915934426 161123.06361884574 219300.78223823328 150795.26467750402 133796.54593338142 155010.3747712535 116210.6315682779 123603.054100007 141447.58081305574 129562.24661064224 2.0346698676162878 1.243595783755197 1.6926287400470248 1.1638827561447804 1.0326815830499143 1.1964162310112407 0.8969482592989582 0.954005177692359 1.0917345485535694 1.0 16.983285864245772 -1.5228787452837256 0.391131966414872 0.965659053214008 15.71187435034092 0.7358724170600976 0.17543487785679707 35.351454439926144 0.47529812596722215 0.1255316443702628 398.8342547177783 0.029999999999765964 1.5228787452837256 14.746215297126913 up KASSPSPLT(ph)IGTPESQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KASSPSPLTIGTPESQR 17 1 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 KAS(0.003)S(0.051)PS(0.133)PLT(0.813)IGTPESQR 120.99 0.00026559 5036300.0 22715.0 17264.0 23426.0 29328.0 29964.0 28271.0 22182.0 29336.0 22950.0 21003.0 True False 26560.200858299795 18977.85582619878 23984.56468359973 27684.847242658903 24092.769298373772 26788.41899174885 20080.76037622724 28565.961084061317 23285.60033286564 24810.677640343485 1.0705149308421746 0.7649067913945152 0.9667033295616057 1.1158440589160639 0.971064541147302 1.0797133145686215 0.8093596098953321 1.1513575525084225 0.938531412580284 1.0 14.598673518851225 -5.517104367630455 24.88159303009672 1.0112174586355087 0.9047344067658077 0.09193275695557335 0.11405285547090754 442.7515476183927 1907798.3895855567 0.028677325965246647 0.05181277378971387 3.0401543421275453e-06 5.517104367630455 -0.10648305186970097 KASTAPGAEAS(ph)PSPCITER ddPTM_PC-9_AZD4547_30min_R2 1 KASTAPGAEASPSPCITER 19 1 Q66PJ3 Q66PJ3 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 KASTAPGAEAS(0.899)PS(0.097)PCIT(0.004)ER 89.079 0.00049422 10060000.0 25255.0 23930.0 38332.0 52118.0 49825.0 33186.0 27364.0 38145.0 22625.0 32158.0 True False 33285.564663366866 31664.90452334479 37823.69263431614 40103.0003150732 42907.65879210359 31110.874173858327 29799.34298890787 32250.566734898697 23820.911310147054 31032.158208133416 1.0726152025946696 1.0203900196360025 1.2188547242067969 1.292304584363789 1.3826836826598043 1.0025365933364017 0.9602729784065605 1.039262771174128 0.7676201941991802 1.0 14.921476415697294 -6.949190915077999 11.069710807222627 0.9502274304857887 1.1940658546709342 0.5282962455053017 0.11602080038153226 0.5239873013484679 112.08215600419045 0.04427904735866568 0.03904102928866708 1.1241107082775743e-07 6.949190915077999 0.24383842418514545 KASTAPGAEASPS(ph)PCITER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KASTAPGAEASPSPCITER 19 1 Q66PJ3 Q66PJ3 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 KASTAPGAEAS(0.038)PS(0.959)PCIT(0.003)ER 102.73 0.00014979 5314200.0 21036.0 17657.0 19940.0 26521.0 32151.0 30053.0 29073.0 30766.0 25564.0 21991.0 True False 24596.97932006141 19409.87026895226 20415.4452228711 25035.1143522421 25851.242347884632 28476.967774717134 26318.99496970761 29958.42509927154 25937.825137663487 25977.794219339794 0.946846337775268 0.7471716076071662 0.7858806275273492 0.9637120896740381 0.9951284596995942 1.0962042248189328 1.0131343233950865 1.153232058361917 0.9984614135696498 1.0 14.664991315958048 -6.0335020415816585 2.221503274693827 1.05434764688642 0.8191415103068017 0.6619402912184709 0.06826076156852613 0.1677649387637846 1.6510649966379822 0.0210063255954546 0.031803905206139044 9.257590331956145e-07 6.0335020415816585 -0.2352061365796182 KASTAPGAEASPS(ph)PCITER ddPTM_PC-9_Lapatinib_30min_R1 1 KASTAPGAEASPSPCITER 19 1 Q66PJ3 Q66PJ3 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 KASTAPGAEAS(0.006)PS(0.974)PCIT(0.02)ER 157.38 6.237000000000001e-06 11793000.0 38329.0 26752.0 35581.0 27963.0 29792.0 29753.0 20936.0 20909.0 29910.0 25743.0 True False 37782.42143132224 26690.057387637993 32655.667526631914 30019.492301833452 28039.6931333256 28480.53354763054 22019.96363936526 21880.508472057285 26541.22083373691 30192.64324960867 1.2513783943647245 0.883992076049318 1.0815769674970463 0.9942651278874876 0.9286928905666126 0.9432938120778703 0.7293155308504056 0.7246966849231022 0.8790625124907178 1.0 14.881909444323247 -6.521485398719328 1.1960787669850244 0.8175143568640952 1.057820268695269 0.4072096718946896 0.11452317032163452 0.43864196921643805 1.316770270773449 0.050697078810719845 0.05751101955350322 3.0096403533612315e-07 6.521485398719328 0.24030591183117367 KASVVDPS(ph)TESSPAPQEGSEQPASPASPLSSR ddPTM_PC-9_Lapatinib_30min_R1 1 KASVVDPSTESSPAPQEGSEQPASPASPLSSR 32 1 Q66K14;Q66K14-2 Q66K14 TBC1D9B TBC1 domain family member 9B 1 KAS(0.374)VVDPS(0.395)T(0.126)ES(0.074)S(0.031)PAPQEGSEQPASPASPLSSR 67.311 2.6228e-05 7234600.0 34617.0 34241.0 35477.0 30309.0 23411.0 22201.0 15081.0 16048.0 23002.0 25609.0 True False 34123.35523201967 34161.71706826076 32560.218005180268 32538.02496786005 22034.01100779689 21251.5149830587 15861.820388100272 16793.64866610433 20411.27253820184 30035.481528152453 1.1361014871706194 1.137378704457951 1.0840584651410154 1.0833195711332926 0.7335993926764339 0.7075470044700137 0.5281027498504688 0.5591269995243304 0.6795720094938454 1.0 14.874380172853115 -6.29692333093769 2.586378890015271 0.6579104502508185 1.1222546230275428 0.7269969059056858 0.12198488846082602 0.136887293199271 1.8096175971444035 0.039052992000229096 0.04814658951242761 5.047503968396166e-07 6.29692333093769 0.46434417277672424 KASVVDPSTES(ph)SPAPQEGSEQPASPASPLSSR ddPTM_PC-9_AZD4547_30min_R2 2 KASVVDPSTESSPAPQEGSEQPASPASPLSSR 32 1 Q66K14;Q66K14-2 Q66K14 TBC1D9B TBC1 domain family member 9B 1 KAS(0.171)VVDPS(0.083)T(0.083)ES(0.331)S(0.331)PAPQEGSEQPASPASPLSSR;KAS(0.039)VVDPS(0.134)T(0.029)ES(0.399)S(0.399)PAPQEGSEQPASPASPLSSR 128.47 2.0718000000000002e-16 21645000.0 70192.0 57705.0 61927.0 73541.0 81172.0 54649.0 44115.0 74508.0 51143.0 59343.0 True False 92511.59591570188 76357.01276722149 61105.80751761703 56587.258647123825 69902.66893071013 51231.789390923346 48041.149537921 62994.5006235111 53846.31456949615 57265.4196326034 1.6154879595614013 1.333387815144002 1.0670629484539245 0.9881575828863136 1.2206785417654018 0.8946374569436513 0.838920763108655 1.100044337885999 0.9402937220220662 1.0 15.80537659384545 -4.275827595228679 0.8405319441311122 0.9816543387740524 2.668900479069998 0.7986830208617619 0.09974476331634947 2.1745443417903307 0.6571951543727497 0.036498740552270925 4.156792421184293 5.29873749655111e-05 4.275827595228679 1.6872461402959458 KASVVDPSTES(ph)SPAPQEGSEQPASPASPLSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KASVVDPSTESSPAPQEGSEQPASPASPLSSR 32 1 Q66K14;Q66K14-2 Q66K14 TBC1D9B TBC1 domain family member 9B 1 KAS(0.036)VVDPS(0.042)T(0.042)ES(0.44)S(0.44)PAPQEGSEQPASPASPLSSR 102.06 9.6788e-14 9332500.0 44020.0 41529.0 30827.0 31782.0 31806.0 28582.0 17254.0 25545.0 17422.0 17352.0 True False 51471.71656536903 45651.724664400455 31562.032592048523 30001.35757863424 25573.84262128143 27083.109604264657 15619.576211857582 24874.470817164773 17676.763790814173 20497.780241643566 2.5110873449993574 2.2271545565530944 1.539778074502266 1.4636393416728646 1.247639613645836 1.3212703661073626 0.7620130583761768 1.2135202214057044 0.8623745392148279 1.0 14.323180064511071 -4.266765920052018 0.4814764707814843 0.957839367291138 4.698906211443395 0.9214727893504908 0.14987140767407117 1.778520129507086 0.21958518416999304 0.09051194196551388 4.182672323549198 5.410458621378485e-05 4.266765920052018 3.7410668441522574 up KASVVDPSTESSPAPQEGSEQPASPAS(ph)PLSSR ddPTM_PC-9_AZD4547_30min_R2 2 KASVVDPSTESSPAPQEGSEQPASPASPLSSR 32 1 Q66K14;Q66K14-2 Q66K14 TBC1D9B TBC1 domain family member 9B 1 KASVVDPSTESSPAPQEGSEQPAS(0.072)PAS(0.726)PLS(0.04)S(0.161)R;KASVVDPSTESSPAPQEGSEQPASPAS(0.796)PLS(0.102)S(0.102)R 188.06 9.5707e-30 60515000.0 135011.0 130401.0 213388.0 329640.0 282230.0 245981.0 194877.0 256384.0 190675.0 217771.0 True False 177941.68959674565 172550.57311946014 210558.33569475744 253646.59088723155 243047.23614441397 230599.76918459125 212220.675473228 216765.74391821408 200753.69122927228 210146.90357433373 0.8467490435032922 0.821095006324588 1.0019578309907295 1.206996565607311 1.1565587311089864 1.0973265142734918 1.0098682010708797 1.0314962544358361 0.9553016857003612 1.0 17.68103867358259 -5.370752461804523 4.050759680735726 1.0714144321731123 0.8339566700521541 0.6146762608773085 0.07180081856670183 0.151523342840241 4.255808473277855 0.021114984598859132 0.04760769477180025 4.258410639096354e-06 5.370752461804523 -0.23745776212095815 KASVVDPSTESSPAPQEGSEQPASPAS(ph)PLSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KASVVDPSTESSPAPQEGSEQPASPASPLSSR 32 1 Q66K14;Q66K14-2 Q66K14 TBC1D9B TBC1 domain family member 9B 1 KASVVDPSTESSPAPQEGS(0.003)EQPAS(0.113)PAS(0.739)PLS(0.072)S(0.072)R;KASVVDPSTESSPAPQEGSEQPAS(0.008)PAS(0.574)PLS(0.082)S(0.337)R 151.44 6.3448e-18 47312000.0 60756.0 58270.0 86413.0 105656.0 123742.0 128235.0 105725.0 99608.0 114508.0 88445.0 True False 71040.79081430157 64054.66050698581 88473.4136431274 99736.43686137386 99495.64338937937 121510.13085518415 95709.96261728552 96993.39554340005 116182.46287214705 104479.37836976523 0.6799503588438244 0.6130842421390428 0.8468026420487421 0.9546040416549425 0.9522993431034036 1.1630058749502223 0.9160655826124494 0.9283496615009388 1.1120133435419495 1.0 16.67285869272854 -5.531895435665888 1.845052976430344 1.0082034132386206 0.6349342220473848 0.7776434848297271 0.07628449283974836 0.16359892695093953 1.0843403058475187 0.022785777685214965 0.061833548556458305 2.9383570299602948e-06 5.531895435665888 -0.3732691911912358 KASVVDPSTESSPAPQEGSEQPASPAS(ph)PLSSR ddPTM_PC-9_Lapatinib_30min_R1 2 KASVVDPSTESSPAPQEGSEQPASPASPLSSR 32 1 Q66K14;Q66K14-2 Q66K14 TBC1D9B TBC1 domain family member 9B 1 KASVVDPSTESSPAPQEGSEQPASPAS(0.869)PLS(0.065)S(0.065)R;KASVVDPSTESSPAPQEGS(0.001)EQPAS(0.106)PAS(0.534)PLS(0.075)S(0.284)R 179.06 9.700799999999999e-24 69297000.0 194646.0 129430.0 166089.0 133694.0 153537.0 161943.0 126711.0 136824.0 169824.0 96416.0 True False 191870.31234629493 129130.31278715572 152433.80354208063 143526.30275010996 144506.25552535625 155017.07539757132 133271.47557831532 143181.34254056972 150696.63279400006 113081.37713375561 1.6967454519000569 1.1419237725980027 1.3480009476872388 1.269230233907952 1.2778961415939467 1.3708453091636217 1.1785448581925062 1.2661796855481438 1.3326388182888165 1.0 16.787001832332457 -14.522878744293294 0.05984598024826908 2.8208374394626207e-06 1.7420319695567597 0.3834544735950055 0.13525622308141794 470.2120352040382 2.048285869887299 70.92340241151231 11.819723578263112 3.000000006818255e-15 14.522878744293294 1.7420291487193202 KAVPMAPAPAS(ph)PGSSNDSSAR ddPTM_PC-9_AZD4547_30min_R2 7 KAVPMAPAPASPGSSNDSSAR 21 1 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 KAVPMAPAPAS(0.817)PGS(0.077)S(0.024)NDS(0.041)S(0.041)AR;KAVPMAPAPAS(0.569)PGS(0.092)S(0.026)NDS(0.156)S(0.156)AR;KAVPMAPAPAS(0.851)PGS(0.032)S(0.011)NDS(0.053)S(0.053)AR;KAVPMAPAPAS(0.785)PGS(0.005)S(0.008)NDS(0.101)S(0.101)AR;KAVPMAPAPAS(0.948)PGS(0.027)S(0.008)NDS(0.008)S(0.008)AR;KAVPMAPAPAS(0.919)PGS(0.032)S(0.012)NDS(0.019)S(0.019)AR;KAVPMAPAPAS(0.925)PGS(0.022)S(0.032)NDS(0.011)S(0.011)AR 161.22 2.9258e-16 87221600.0 227029.0 175402.0 324360.0 579214.0 458192.0 320779.0 241296.0 337436.0 255024.0 325459.0 True False 299219.49950344505 232097.2663269422 320058.774466941 445685.16106709384 394579.94976962334 300720.63842030015 262770.87654770905 285293.0197078851 268504.04799818515 314064.7794720094 0.9527317899398923 0.7390108076338039 1.019085218676887 1.4190867305030457 1.2563648506940899 0.9575115010535636 0.8366773153916425 0.9083890915355297 0.8549320571685283 1.0 18.260702636687675 -6.989163007503388 24.89187775020116 0.8930409275508515 1.0774948876827997 0.1924357529486871 0.17278118974074805 389.45043376582873 894538.3305591606 0.07008192561150632 0.06174899962700274 1.025267031682182e-07 6.989163007503388 0.18445396013194815 KAVPMAPAPAS(ph)PGSSNDSSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KAVPMAPAPASPGSSNDSSAR 21 1 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 KAVPMAPAPAS(0.903)PGS(0.046)S(0.017)NDS(0.017)S(0.017)AR;KAVPMAPAPAS(0.399)PGS(0.174)S(0.078)NDS(0.174)S(0.174)AR;KAVPMAPAPAS(0.408)PGS(0.148)S(0.148)NDS(0.148)S(0.148)AR 109.18 1.7749000000000002e-05 42418700.0 71116.0 41696.3 65948.0 93633.0 100463.0 109783.0 91422.0 111537.0 96678.0 78911.0 True False 83154.53419497445 45835.63310275329 67520.45042918267 88387.04657228176 80777.99632967956 104025.78621807377 82761.84632203785 108609.27193322017 98091.73285319321 93216.93964086765 0.8920538961624341 0.49170926742866683 0.7243366998457085 0.948186530396795 0.8665591966534086 1.115953673429409 0.8878412726366084 1.165123767757811 1.0522951432551468 1.0 16.508304528798128 -5.993086726379026 1.3938690368272002 1.0373729689089057 0.671098186194895 0.5565186626983434 0.12445407685386158 0.2912605645024869 1.147432064116868 0.04283716140110387 0.07777353752072237 1.0160457734842648e-06 5.993086726379026 -0.3662747827140107 KAVPMAPAPAS(ph)PGSSNDSSAR ddPTM_PC-9_Lapatinib_30min_R1 5 KAVPMAPAPASPGSSNDSSAR 21 1 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 KAVPMAPAPAS(0.984)PGS(0.002)S(0.001)NDS(0.007)S(0.007)AR;KAVPMAPAPAS(0.997)PGS(0.001)SNDS(0.001)S(0.001)AR;KAVPMAPAPAS(0.615)PGS(0.183)S(0.067)NDS(0.067)S(0.067)AR;KAVPMAPAPAS(0.532)PGS(0.287)S(0.084)NDS(0.048)S(0.048)AR;KAVPMAPAPAS(0.478)PGS(0.252)S(0.09)NDS(0.09)S(0.09)AR 188.08 1.5186e-15 56587300.0 344734.0 162939.0 226487.0 194624.0 190900.0 189616.0 146504.0 134589.0 237844.0 139208.0 True False 339818.02994352655 162561.72475644198 207866.11312510312 208937.2982066318 179671.63732384052 181506.56569648485 154089.26027042267 140842.49628130076 211055.50411164592 163269.91731699964 2.0813266493162166 0.9956624430746623 1.2731439847643025 1.279704808087615 1.100457697758221 1.1116963166219869 0.9437700637236676 0.8626359258077254 1.2926784528338269 1.0 17.316899471487062 -4.757792220640665 24.99993594694167 1.0984580227948424 2.081328040038965 0.8130661430075486 0.1417984226245262 45.29708046810341 310448.67523824016 0.03690683775404731 0.26635028759441753 1.7466576058483713e-05 4.757792220640665 0.9828700172441227 KAVPMAPAPASPGS(ph)SNDSSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KAVPMAPAPASPGSSNDSSAR 21 1 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 KAVPMAPAPAS(0.266)PGS(0.393)S(0.178)NDS(0.082)S(0.082)AR 45.323 0.027681 12261000.0 36388.0 23149.0 35583.0 48870.0 48129.0 55851.0 51394.0 57825.0 51571.0 45012.0 True False 42547.769704240076 25447.07973358873 36431.43366927895 46131.9723386777 38698.46794691735 52922.07523993367 46525.58825966197 56307.155020651895 52325.128312253364 53172.319285204045 0.800186455588361 0.4785775771242264 0.6851578821279011 0.8675937585350838 0.7277934923121879 0.9952937158161539 0.8749964057446781 1.0589561594752586 0.9840670675204791 1.0 15.698387775221423 -6.397758655880791 0.7711167680803226 1.0097730737334798 0.6225909856253611 0.6421145750166927 0.10163833713489143 0.40860039881600263 0.5354979979652444 0.05904597052688041 0.08684982219525618 4.00167066972984e-07 6.397758655880791 -0.3871820881081187 KAVPVES(ph)PVQKV ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KAVPVESPVQKV 12 2 Q8TB61-5;Q8TB61-4;Q8TB61-3;Q8TB61-2;Q8TB61 Q8TB61-5 SLC35B2 Adenosine 3-phospho 5-phosphosulfate transporter 1 1 KAVPVES(1)PVQKV 95.06700000000001 0.0099896 0.0 38510.0 29097.0 32595.0 31439.0 52860.0 36103.0 35657.0 26634.0 34022.0 27330.0 True False 45028.98239282967 31985.55786462616 33372.18841722589 29677.574756613216 42502.46245868501 34209.69512430084 32279.31082567551 25934.88572105566 34519.50738669956 32284.712655839034 1.394746264984511 0.9907338561627629 1.0336839225728767 0.919245435850138 1.3164887949218897 1.0596252006013642 0.9998326814854724 0.8033178426435541 1.0692214533449267 1.0 14.978563566249367 -7.272219930416851 3.4941691041050693 0.9469071597268547 1.111304777560715 0.200398386226862 0.14864184693180527 0.401178590768209 10.544716057866577 0.0642298702919109 0.04416618519170295 5.3429371999476104e-08 7.272219930416851 0.1643976178338603 KAVVLPGGTAT(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 1 KAVVLPGGTATSPK 14 1 Q8N1G0;Q8N1G0-2;F8WCX2;H0Y5I5 Q8N1G0 ZNF687 Zinc finger protein 687 1 KAVVLPGGT(0.056)AT(0.589)S(0.356)PK 83.633 0.026720999999999998 5515300.0 50494.0 41772.0 41946.0 56115.0 45346.0 39967.0 48942.0 43869.0 43467.0 51435.0 True False 66550.04165955438 55273.982104018345 41389.76863297048 43178.5537181076 39050.490628935884 37467.85717189765 53297.74318678295 37090.05405933338 45764.57688036077 49634.276305595566 1.3408081393150442 1.1136252247076075 0.833894874947625 0.8699341852444784 0.7867645815666601 0.7548786838597197 1.0738092131862993 0.7472669457487788 0.9220357439804449 1.0 15.599049136805919 -4.986627939507629 2.4432280244054287 0.8635767712385892 1.3611756901285066 0.6890043497099301 0.10030308603833993 0.1904173956957136 1.9168136218530023 0.025739146510949582 0.16654686620957349 1.0312692314300862e-05 4.986627939507629 0.49759891888991736 KAVVLPGGTATS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 KAVVLPGGTATSPK 14 1 Q8N1G0;Q8N1G0-2;F8WCX2;H0Y5I5 Q8N1G0 ZNF687 Zinc finger protein 687 1 KAVVLPGGT(0.003)AT(0.218)S(0.779)PK 95.18299999999999 0.0047902000000000005 5618000.0 52785.0 57600.0 56825.0 74844.0 67218.0 60214.0 64371.0 72347.0 62747.0 68270.0 True False 69569.53200379397 76218.07357060854 56071.46337120457 57589.87212827304 57885.940967137394 56448.809061191576 70099.89429684951 61167.43351867126 66063.67831946065 65879.88807977077 1.0560056191892067 1.1569247579522262 0.8511165547717742 0.8741646928504228 0.878658763005883 0.8568443375744725 1.0640560623292035 0.9284689956456298 1.0027897776551675 1.0 16.007550483689357 -5.256365284831571 24.99156584935127 0.9275175137470519 1.1064651980694025 0.48897388127652863 0.07121878952331782 342.57665262568037 1687287.5495606356 0.018889429262642525 0.04691395552867048 5.541594137286437e-06 5.256365284831571 0.17894768432235053 KAVVLPGGTATS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KAVVLPGGTATSPK 14 1 Q8N1G0;Q8N1G0-2;F8WCX2;H0Y5I5 Q8N1G0 ZNF687 Zinc finger protein 687 1 KAVVLPGGTAT(0.039)S(0.961)PK 135.86 6.7992e-05 3946100.0 64832.0 65567.0 57928.0 78648.0 76480.0 69370.0 77835.0 78348.0 61699.0 66130.0 True False 75806.77710963215 72076.05844279284 59309.22321316339 74241.60754025614 61494.29301627368 65732.11508109437 70461.90532339952 76291.4480165678 62601.23115195977 78118.84551520793 0.9704031928489565 0.9226462317439306 0.7592178663420884 0.9503674439966349 0.787188963312344 0.8414373592899277 0.9019834440548948 0.9766074692145268 0.8013588877190045 1.0 16.25338300796269 -10.69410995426421 6.174964829646337 1.0000009258246958 0.8786200398098284 0.19143978214518964 0.07458276334125921 9.327621805656648e-07 1.252549208351161e-07 0.07085952460401874 0.017185828102319417 2.0225070574370476e-11 10.69410995426421 -0.1213808860148674 KAVVLPGGTATS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 KAVVLPGGTATSPK 14 1 Q8N1G0;Q8N1G0-2;F8WCX2;H0Y5I5 Q8N1G0 ZNF687 Zinc finger protein 687 1 KAVVLPGGTAT(0.021)S(0.979)PK;KAVVLPGGT(0.002)AT(0.494)S(0.504)PK 154.31 0.00013351 83292000.0 857450.0 677870.0 606440.0 629390.0 631180.0 567840.0 610940.0 574350.0 610920.0 548710.0 True False 845222.6057629271 676300.4336632091 556580.8441260955 675677.4401834902 594055.2333476249 543554.8068996918 642571.4838476211 601036.397767759 542111.7563271997 643553.7923898845 1.3133674539064257 1.05088407785108 0.8648552004630281 1.0499160259382703 0.9230855918687961 0.8446144103683407 0.9984736185943129 0.9339334254185125 0.8423720949790813 1.0 19.295701217708938 -4.8196726081198715 2.754492242088583 0.932994629637758 1.3680520540456425 0.7521295784412851 0.0663549131053165 0.18700381100326158 2.063148023834839 0.016713170175675567 0.1805753536692333 1.5147026732219212e-05 4.8196726081198715 0.4350574244078844 KAVVQSPQVT(ph)EVL ddPTM_PC-9_AZD4547_30min_R2 1 KAVVQSPQVTEVL 13 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 KAVVQSPQVT(1)EVL 96.14299999999999 0.011381 10369000.0 51444.0 40657.0 56492.0 69086.0 61859.0 58278.0 41170.0 67260.0 52216.0 54636.0 True False 67802.12189832682 53798.58015903171 55742.87916878292 53159.290068059854 53270.94561406393 54633.86744724025 44834.05024314198 56866.51248104034 54976.03115892324 52723.21026990411 1.286001393906588 1.0203965176555543 1.0572739953318533 1.0082711161919642 1.0103888845416622 1.0362393937613998 0.8503664707369785 1.0785859243002383 1.0427292055526651 1.0 15.68615059700212 KAVVQSPQVT(ph)EVL ddPTM_PC-9_Lapatinib_30min_R1 1 KAVVQSPQVTEVL 13 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 KAVVQSPQVT(1)EVL 96.14299999999999 0.011381 7661600.0 61930.0 51065.0 54789.0 49088.0 46148.0 48269.0 42586.0 38383.0 50231.0 35056.0 True False 61046.86684342894 50946.762129924224 50284.45991165611 52698.09527276762 43433.66537045882 46204.6473905347 44790.89470510169 40166.41430403055 44573.45582412034 41115.382890816174 1.484769508423204 1.2391168109808375 1.2230084308150273 1.2817123803202777 1.0563847960700974 1.1237800585059199 1.0893950525535907 0.9769193785862178 1.0841065482106111 1.0 15.327390643728215 -1.5228787452853336 0.28063567845507953 0.9981622259248502 4.4036440292148376 0.8311532406689187 0.0598665259221771 20.100140979194958 0.2834578548387935 0.06554952882382523 33.58953653278108 0.029999999999654886 1.5228787452853336 3.4054818032899874 KAWENS(ph)PNVR ddPTM_PC-9_AZD4547_30min_R2 1 KAWENSPNVR 10 1 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3;H7C5N8;A0A2R8Y7F4;A0A2R8YET2 E7EPN9 PRRC2C Protein PRRC2C 1 KAWENS(1)PNVR 63.966 0.024233 5831200.0 18590.0 17693.0 20412.0 27973.0 28933.0 19779.0 15284.0 29248.0 21305.0 26789.0 True False 24501.233303978996 23411.91624452734 20141.32354303614 21524.257028541815 24916.15236993343 18542.21600327678 16644.246390968703 24728.393652177674 22431.13880498046 25851.125263937 0.9477820811985643 0.9056439905611219 0.7791275365151634 0.8326236018270632 0.9638324102158956 0.7172692025574476 0.6438499763949489 0.9565693330446405 0.8677045419091481 1.0 14.657939459987865 -8.564538497497233 1.614928101183089 0.9947371130870187 0.8342630843858372 0.17881299867942346 0.10087577238489222 0.7775172922956192 4.491069206380533 0.1008695841387531 0.029221954274513882 2.7255961211224666e-09 8.564538497497233 -0.16047402870118155 KAYGQALAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KAYGQALAK 9 1 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 63.534 0.036124 6451700.0 31989.0 32509.0 42959.0 46643.0 46276.0 51359.0 36720.0 37825.0 42233.0 32858.0 False True 37404.10588845047 35736.27867550372 43983.305482914766 44029.743928646276 37208.54999504556 48665.64362764777 33241.61577022199 36832.13382890027 42850.57772801371 38814.89529621512 0.9636534016902985 0.9206846599168439 1.1331553298613077 1.134351737719093 0.9586152354937256 1.2537878372788809 0.8564138977199152 0.9489175108632021 1.1039725188230023 1.0 15.244322775419572 -10.076370668488984 11.573257601025787 1.0000124177358876 1.0301936057927 0.006107925885531773 0.11629110164322269 0.0 0.0 0.11233249728319976 0.027244632440473038 8.387438166668053e-11 10.076370668488984 0.030181188056812358 KAYGQALAK ddPTM_PC-9_Lapatinib_30min_R1 1 KAYGQALAK 9 1 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 86.67 0.0072664 10112000.0 89437.0 78732.0 86248.0 82319.0 68874.0 81619.0 79747.0 61237.0 80333.0 75547.0 False True 88161.61197926303 78549.7008912798 79157.02236690791 88373.01386813378 64822.9667314939 78128.34563318187 83875.90945493229 64082.294576659384 71285.0515960076 88605.19828995023 0.9949936762261328 0.8865134597886122 0.8933677018347811 0.99737956207652 0.7315932697240659 0.8817580361088514 0.9466251537574365 0.7232340293055664 0.8045244858290993 1.0 16.43510372084821 -6.242413210345502 24.99728068368947 0.8407410953640254 0.9354745914698965 0.2159812465206209 0.08765555591286422 1325.7614786297631 1741834.2240172313 0.025587698816622928 0.03297952781165213 5.722513022496783e-07 6.242413210345502 0.09473349610587112 KAYS(ph)FCGTVEYMAPEVVNR ddPTM_PC-9_AZD4547_30min_R2 2 KAYSFCGTVEYMAPEVVNR 19 1 B4DG22;B1AXG1;B7ZB17;P51812;Q9UK32-2;Q9UK32;E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2 B4DG22;E9PGT3 RPS6KA3;RPS6KA6;RPS6KA1 Ribosomal protein S6 kinase alpha-3;Ribosomal protein S6 kinase alpha-6;Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 KAY(0.01)S(0.961)FCGT(0.029)VEYMAPEVVNR;KAY(0.047)S(0.885)FCGT(0.068)VEYMAPEVVNR 75.404 0.0018558 70481000.0 166643.0 123015.0 196732.0 293290.0 233187.0 165636.0 157024.0 213514.0 142228.0 176736.0 True False 219632.00761027282 162777.19306056242 194123.20513759454 225676.52178532988 200813.01015061236 155278.75473576787 170998.8318042053 180520.31736361695 149745.88171578306 170548.5264342518 1.2877977441508015 0.9544333009720531 1.1382285687025917 1.3232393530666504 1.1774537977496264 0.9104667040065539 1.002640335741201 1.058468936307165 0.8780250691495223 1.0 17.37982276433283 -6.750779324373485 24.925008624248562 0.975619527201297 1.1699644604692998 0.49811695271943024 0.10336970520060629 194.14248655347183 453937.37946926797 0.03531271879829482 0.03496302253542874 1.7750912189479803e-07 6.750779324373485 0.19434493326800284 KAYS(ph)FCGTVEYMAPEVVNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KAYSFCGTVEYMAPEVVNR 19 1 B4DG22;B1AXG1;B7ZB17;P51812;Q9UK32-2;Q9UK32;E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2 B4DG22;E9PGT3 RPS6KA3;RPS6KA6;RPS6KA1 Ribosomal protein S6 kinase alpha-3;Ribosomal protein S6 kinase alpha-6;Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 KAY(0.393)S(0.599)FCGT(0.008)VEYMAPEVVNR 52.227 0.021491 5622600.0 21171.0 12695.0 19445.0 24838.0 28824.0 29592.0 28763.0 28454.0 28853.0 21445.0 True False 24754.83215368987 13955.275701667835 19908.642545573148 23446.407385882474 23176.14411481531 28040.14342626127 26038.360413913244 27707.11264950505 29274.920540486804 25332.808741473393 0.977184662242474 0.5508775534558501 0.7858837426495027 0.9255352466107474 0.914866738676027 1.106870687432128 1.0278513006449523 1.093724463491669 1.1556128986423688 1.0 14.628719422361716 -6.233891553403543 1.268501970012152 1.0822234979952474 0.7482556559051557 0.5769709279388316 0.10975504518902345 0.2953879095745523 0.9681308118381725 0.042140136020303684 0.0621420437449696 5.835908130932178e-07 6.233891553403543 -0.33396784209009167 KAYS(ph)FCGTVEYMAPEVVNR ddPTM_PC-9_Lapatinib_30min_R1 2 KAYSFCGTVEYMAPEVVNR 19 1 B4DG22;B1AXG1;B7ZB17;P51812;Q9UK32-2;Q9UK32;E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2 B4DG22;E9PGT3 RPS6KA3;RPS6KA6;RPS6KA1 Ribosomal protein S6 kinase alpha-3;Ribosomal protein S6 kinase alpha-6;Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 KAY(0.067)S(0.927)FCGT(0.006)VEYMAPEVVNR;KAY(0.097)S(0.885)FCGT(0.018)VEYMAPEVVNR 75.764 0.0018043 46316000.0 174633.0 129238.0 170269.0 156494.0 168395.0 155108.0 140654.0 128944.0 179996.0 125565.0 True False 172142.70139623 128938.75735135932 156270.14007734688 168003.09080868048 158490.33717730799 148474.3924144078 147936.37589469226 134935.20897321502 159722.95503809137 147268.74294515452 1.168901818224516 0.8755337675380199 1.0611222514172247 1.1407925908028413 1.076198071686757 1.008186730226266 1.0045334327990183 0.9162515159341537 1.0845679255751848 1.0 17.168091732487355 -6.8755964141181645 5.252905543480372 0.9960308376927449 1.0578671672105926 0.12077348294184287 0.0819279049827807 0.5010129809389711 21.074808322991213 0.029441478615988517 0.025977357614083804 1.3316913717313214e-07 6.8755964141181645 0.06183632951784768 KCLCRLLT(ph)NAPR ddPTM_PC-9_Lapatinib_30min_R1 1 KCLCRLLTNAPR 12 2 B4DPR9;Q99551 B4DPR9 MTERF1 Transcription termination factor 1, mitochondrial 1 KCLCRLLT(1)NAPR 57.174 0.034703 6449700.0 34304.0 33180.0 34393.0 34001.0 38927.0 32608.0 27340.0 32113.0 33974.0 28237.0 True False 33814.81866941685 33103.17374857312 31565.34030081928 36501.54696401102 36637.39039342659 31213.431852960613 28755.531424352605 33605.08721427021 30147.490357919705 33117.72782656256 1.021048872872709 0.9995605351289298 0.953125180149039 1.102175461890668 1.106277296114531 0.9424991960929585 0.8682821350228264 1.0147159669364985 0.9103127640821865 1.0 15.015316073950709 -6.8004564647508445 24.459559749961468 0.9431516217892836 1.0334123963324127 0.3762723948789778 0.05728869755841717 145.66055479299453 91312.44703581162 0.02105905456135279 0.01857268639903858 1.5832282672779772e-07 6.8004564647508445 0.09026077454312909 KCS(ph)LPAEEDSVLEK ddPTM_PC-9_AZD4547_30min_R2 5 KCSLPAEEDSVLEK 14 1 E7EVA0;P27816;P27816-6 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 KCS(1)LPAEEDSVLEK;KCS(1)LPAEEDSVLEK;KCS(1)LPAEEDSVLEK;KCS(0.984)LPAEEDS(0.016)VLEK;KCS(0.997)LPAEEDS(0.003)VLEK 101.45 0.00078201 599960000.0 383621.0 336650.0 411148.0 480424.0 479067.0 424564.0 398331.0 412729.0 385600.0 443215.0 True False 505604.4981875059 445465.5289504395 405695.9088806691 369669.66927680885 412556.81634835317 398015.9459636582 433781.6873306036 348951.21661890246 405982.02878199785 427698.17775414564 1.182152565723914 1.0415417977452948 0.9485565522186439 0.8643236948493772 0.9645980221723175 0.9306000508434485 1.0142238379606914 0.8158819344315528 0.9492255284177739 1.0 18.706233534934533 -4.895739290976081 1.9601709678941004 0.9295697887710642 1.2238765530649565 0.6547034154440834 0.055858829868713135 0.34277032406322905 1.7336003364398134 0.01484845692932264 0.1702929373569945 1.2713370658124614e-05 4.895739290976081 0.29430676429389224 KCS(ph)LPAEEDSVLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 KCSLPAEEDSVLEK 14 1 E7EVA0;P27816;P27816-6 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 KCS(0.997)LPAEEDS(0.003)VLEK;KCS(1)LPAEEDSVLEK;KCS(1)LPAEEDSVLEK;KCS(1)LPAEEDSVLEK;KCS(1)LPAEEDSVLEK;KCS(1)LPAEEDSVLEK 119.51 4.5916000000000006e-05 478100000.0 654622.0 646431.0 576732.0 691597.0 710925.0 639120.0 688949.0 687933.0 592091.0 506319.0 True False 765436.5752261478 710604.3975663527 590483.4781482904 652849.0622777275 571624.349667814 605603.4220935425 623686.7631611833 669875.4876752654 600749.2107488775 598110.6266810007 1.279757524914182 1.188081879617481 0.9872479300776942 1.0915189149881488 0.9557167590213824 1.0125274407079512 1.0427615483478503 1.119985932021469 1.0044115318306894 1.0 19.190052824751966 -5.0773306987538165 3.4348699607137623 1.0310718015820066 1.2691789810590952 0.7646414171054492 0.04704241919809953 0.11061232931761437 2.4307570052771736 0.012354913268769807 0.04529275528590602 8.368917781355692e-06 5.0773306987538165 0.2381071794770886 KCS(ph)LPAEEDSVLEK ddPTM_PC-9_Lapatinib_30min_R1 5 KCSLPAEEDSVLEK 14 1 E7EVA0;P27816;P27816-6 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 KCS(1)LPAEEDSVLEK;KCS(1)LPAEEDSVLEK;KCS(1)LPAEEDSVLEK;KCS(1)LPAEEDSVLEK;KCS(0.998)LPAEEDS(0.002)VLEK 102.15 0.0014222000000000002 591006000.0 415962.0 375024.0 409345.0 365857.0 405358.0 367104.0 333237.0 337726.0 375827.0 325087.0 True False 410030.30560191185 374155.6549694052 375690.23421739554 392763.34424317407 381515.6394044911 351403.8176812211 350490.3813188364 353417.9828893794 333497.4056262406 381277.85479880124 1.0754107547585818 0.9813201848999219 0.9853450167349629 1.0301236730636603 1.0006236517612999 0.9216475944207551 0.9192518708011216 0.9269302647432188 0.8746833875317144 1.0 18.540483213998748 -6.723742398295332 4.756260860897447 0.9229650028934608 1.0131325573581835 0.5637628406917461 0.03780232526302062 0.14269745402349635 7.365869465908451 0.01245919997831489 0.012055882862230385 1.8891115430611508e-07 6.723742398295332 0.09016755446472269 KCS(ph)QTQCPR ddPTM_PC-9_AZD4547_30min_R2 1 KCSQTQCPR 9 1 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BVD2;H3BT57;H3BUJ5;H3BRN3;P29590-2 P29590;P29590-2 PML Protein PML 1 KCS(0.972)QT(0.028)QCPR 84.18799999999999 0.019685 4806700.0 2544.7 2003.6 2204.4 4264.4 2263.9 2600.8 2132.3 2358.0 2961.6 3276.4 True False 3353.8616669518765 2651.2245174665113 2175.168215670626 3281.308464323231 1949.5965627585222 2438.171564857792 2322.070569187556 1993.625281449498 3118.1441297737683 3161.694233258545 1.0607798918921003 0.83854551448325 0.6879755141371868 1.0378323209772906 0.6166303313743292 0.7711598228602052 0.7344386894726231 0.630556003954501 0.9862257067661181 1.0 11.626482136390129 -4.784238165999236 3.9448655251117097 0.7907199480538659 1.084837206640016 0.2023804954230506 0.14606720169298804 0.3290328864079291 9.483979606935991 0.034665247902571444 0.2760137745344392 1.6434702011253764e-05 4.784238165999236 0.2941172585861501 KDAPT(ph)SPASVASSSSTPSSK ddPTM_PC-9_AZD4547_30min_R2 1 KDAPTSPASVASSSSTPSSK 20 1 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 KDAPT(0.923)S(0.077)PASVASSSSTPSSK 74.703 0.0020914 6921700.0 44611.0 39580.0 68187.0 89807.0 72612.0 58967.0 56744.0 70842.0 59110.0 62202.0 True False 58796.370033556086 52373.46097091463 67282.79582740567 69103.3836543187 62531.07717435478 55279.78416832107 61794.106072306204 59894.99668721171 62234.43392454327 60024.326912815326 0.9795423465382155 0.8725372472228886 1.120925452860691 1.151256285717133 1.0417622385867065 0.9209563357305839 1.0294843649319294 0.9978453698316107 1.0368201881703414 1.0 15.873259700329374 -5.251698667415428 24.993488753891796 1.0370876904363 0.9260397994218631 0.3193718322952853 0.0650153635351389 882.5075577260677 2264395.9996071164 0.018082180154726273 0.046609682459986174 5.601461206722997e-06 5.251698667415428 -0.1110478910144369 KDAPT(ph)SPASVASSSSTPSSK ddPTM_PC-9_Lapatinib_30min_R1 1 KDAPTSPASVASSSSTPSSK 20 1 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 KDAPT(0.499)S(0.499)PAS(0.002)VASSSSTPSSK 64.843 0.005691300000000001 5320700.0 51582.0 43433.0 54019.0 50864.0 51248.0 51134.0 46250.0 43057.0 53556.0 44330.0 True False 50846.43122101969 43332.43355701557 49577.76633937013 54604.708237329956 48233.6933974446 48947.11801917589 48644.59869701201 45057.58540730642 47523.959310318096 51992.381433987975 0.9779592666971171 0.8334381377016267 0.9535582901182637 1.0502444152641617 0.9277069460394772 0.9414286606840947 0.9356101289334771 0.8666189961795401 0.9140562136138503 1.0 15.66601261679062 -9.788920480716403 14.168964169576538 0.9999999999931698 0.9326608453122196 0.11402436632864776 0.05565740197258567 0.0 0.0 0.05607910552487099 0.013601180909953062 1.6258464208431636e-10 9.788920480716403 -0.0673391546809502 KDAPTSPAS(ph)VASSSSTPSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KDAPTSPASVASSSSTPSSK 20 1 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 KDAPT(0.041)S(0.091)PAS(0.862)VAS(0.003)S(0.002)S(0.001)STPSSK 72.158 0.0015677 4677000.0 15005.0 23360.0 21565.0 25474.0 25429.0 21011.0 23562.0 21202.0 22167.0 18654.0 True False 17545.050137741076 25679.0264191383 22079.19138571793 24046.774367822298 20446.369993603883 19909.146172248416 21330.03678589244 20645.469965375905 22491.15043915611 22035.82253501726 0.7962058194042964 1.1653309686230955 1.0019681067331048 1.0912583058612593 0.9278696069144879 0.9034900394850552 0.9679709823400849 0.9369048935009374 1.0206630772876883 1.0 14.427563128901019 -6.285477006563142 24.764788552708783 0.9539530843263384 1.0236849212415424 0.06911516335491874 0.09334488900162308 1523.5243446192 1569609.1681223111 0.02752591476230511 0.031230881347206862 5.182305286567835e-07 6.285477006563142 0.06973183691520402 KDAS(ph)SSPASTASSASSTSLK ddPTM_PC-9_AZD4547_30min_R2 1 KDASSSPASTASSASSTSLK 20 1 A0A669KBK8;Q04724 A0A669KBK8 TLE1 Transducin-like enhancer protein 1 1 KDAS(0.461)S(0.461)S(0.075)PAS(0.002)T(0.001)ASSASSTSLK 87.352 0.00033685 9692700.0 49997.0 41276.0 52113.0 79486.0 62894.0 59728.0 61577.0 56068.0 52807.0 66177.0 True False 65895.00599779666 54617.659803827 51421.94756997071 61161.73074645812 54162.253729464384 55993.19871801995 67057.2337095446 47403.978914465835 55598.270212372816 63860.16337271118 1.0318640372591814 0.8552696535562937 0.8052273100188218 0.9577446645335994 0.8481383521265635 0.8768095125473332 1.0500636103633834 0.742309076752575 0.8706252423421008 1.0 15.962628623292074 -4.754454565541972 24.82789679665633 0.8843392104897496 1.0318643159474723 0.19319714744114247 0.08663828526842884 362.5465787964683 1288567.863728084 0.020848753504724385 0.2024394701120683 1.7601327934643402e-05 4.754454565541972 0.14752510545772268 KDAS(ph)SSPASTASSASSTSLK ddPTM_PC-9_Lapatinib_30min_R1 3 KDASSSPASTASSASSTSLK 20 1 A0A669KBK8;Q04724 A0A669KBK8 TLE1 Transducin-like enhancer protein 1 1 KDAS(0.433)S(0.433)S(0.134)PASTASSASSTSLK;KDAS(0.333)S(0.333)S(0.333)PASTASSASSTSLK;KDAS(0.64)S(0.177)S(0.177)PAS(0.005)T(0.001)ASSASSTSLK 97.62299999999999 0.00020094 19647400.0 128623.0 112610.0 137296.0 114186.0 125606.0 128095.0 98660.0 101735.0 126589.0 86442.0 True False 126788.81243343055 112349.258463738 126008.05285788636 122583.61935332957 118218.10203089721 122616.6754540294 103768.13205291239 106461.9795018772 112331.21377873373 101383.38452327515 1.2505876878111417 1.1081624369912937 1.242886627334462 1.209109559024313 1.1660500641873641 1.2094356094994996 1.0235220745573923 1.0500929713728004 1.1079844523531883 1.0 16.629461706363415 -7.258709391408767 24.999498771544015 1.049574285317345 1.1947683965153582 0.7282841009632011 0.04552541681934728 130.76008337552568 1197426.3819826453 0.01723384129739276 0.012748924795864914 5.5117639327499054e-08 7.258709391408767 0.14519411119801306 KDASS(ph)SPASTASSASSTSLK ddPTM_PC-9_AZD4547_30min_R2 1 KDASSSPASTASSASSTSLK 20 1 A0A669KBK8;Q04724 A0A669KBK8 TLE1 Transducin-like enhancer protein 1 1 KDAS(0.075)S(0.628)S(0.296)PASTASSASSTSLK 85.777 0.00035137 10125000.0 27393.0 26065.0 47368.0 61191.0 54683.0 49982.0 37320.0 41329.0 40125.0 43894.0 True False 36103.40419020425 34490.00152114423 46739.869370298635 47084.36034152586 47091.20934728749 46856.61763869664 40641.40770158023 34942.55269593994 42245.925583188946 42357.284420293785 0.8523540799255479 0.8142637563568579 1.1034670897812588 1.1116000703521798 1.11176176640648 1.1062233634658407 0.959490398353029 0.8249478967825101 0.9973709637284611 1.0 15.370322478819295 -5.250763466080273 24.810819074208368 1.0270931480708148 0.8333088867379865 0.44690065326751316 0.08612809771489398 673.4593149637641 1565111.1669011633 0.025478693616674444 0.06589931667780444 5.613536281365632e-06 5.250763466080273 -0.19378426133282822 KDASS(ph)SPASTASSASSTSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KDASSSPASTASSASSTSLK 20 1 A0A669KBK8;Q04724 A0A669KBK8 TLE1 Transducin-like enhancer protein 1 1 KDAS(0.365)S(0.574)S(0.061)PASTASSASSTSLK 124.31 4.3694e-06 11331000.0 74224.0 71744.0 74781.0 100290.0 109410.0 92092.0 91668.0 95380.0 93403.0 72229.0 True False 86788.65720917644 78866.27018042217 76564.06264852191 94671.07644456677 87971.89590625666 87262.53340129934 82984.54342115222 92876.3760634635 94768.84217388443 85323.54593555062 1.017171242211763 0.924320119559893 0.8973380303058993 1.109553938558494 1.0310389112602807 1.0227251158456698 0.972586670083248 1.0885198809437424 1.1106997621203922 1.0 16.380656303002567 -5.755929880766625 24.999871597413854 1.0466768096615955 0.9440808299332468 0.45241215779258737 0.0511929908444756 126.07570201974225 572072.7597110688 0.014476406659172493 0.024182238180838308 1.754163698358962e-06 5.755929880766625 -0.10259597972834866 KDASS(ph)SPASTASSASSTSLK ddPTM_PC-9_Lapatinib_30min_R1 1 KDASSSPASTASSASSTSLK 20 1 A0A669KBK8;Q04724 A0A669KBK8 TLE1 Transducin-like enhancer protein 1 1 KDAS(0.072)S(0.556)S(0.372)PASTASSASSTSLK 95.834 0.00023699 7505800.0 86489.0 73930.0 91268.0 79966.0 86757.0 75283.0 65639.0 66710.0 85702.0 64708.0 True False 85255.65099985979 73758.81962724564 83764.29734466833 85846.96639875614 81654.12383082461 72063.32158324448 69037.46624590631 69809.59013682813 76049.3382779312 75892.69158200978 1.123371028522982 0.9718830376116221 1.1037202080802797 1.1311624954820552 1.0759155081828797 0.9495423087659598 0.9096721279321646 0.9198460178657883 1.0020640550843047 1.0 16.21167334126323 -6.759491760418446 7.576400674120022 0.948065528168406 1.0794032471746908 0.610994779989164 0.04964851977833988 0.08527408978171216 32.46182499955384 0.01728422699592367 0.016289014692837115 1.7398357064756567e-07 6.759491760418446 0.13133771900628488 KDASSS(ph)PASTASSASSTSLK ddPTM_PC-9_AZD4547_30min_R2 1 KDASSSPASTASSASSTSLK 20 1 A0A669KBK8;Q04724 A0A669KBK8 TLE1 Transducin-like enhancer protein 1 1 KDAS(0.003)S(0.003)S(0.993)PASTASSASSTSLK 107.41 5.248e-05 4476600.0 19990.0 18925.0 20673.0 32378.0 27650.0 25995.0 21627.0 25288.0 22418.0 24594.0 True False 26346.404182169987 25042.136151454237 20398.862512501768 24913.75233511339 23811.27477374137 24369.528540632997 23551.761102949516 21380.320660430407 23602.96971274591 23732.971545830995 1.1101182222922301 1.0551622708978983 0.8595157362873548 1.0497527579722656 1.0032993436055473 1.0268216305561544 0.992364612137526 0.9008699403335415 0.9945223111722847 1.0 14.5346051276177 -7.532170230130663 24.975559100264597 0.957941121297818 1.0125385971646903 0.10884318382737246 0.0654164136852747 459.3135687056629 1234619.3940016418 0.031173798885943262 0.018029438160359897 2.936498408944632e-08 7.532170230130663 0.05459747586687225 KDDDSDDES(ph)QSSHTGK ddPTM_PC-9_Lapatinib_30min_R1 1 KDDDSDDESQSSHTGK 16 1 O94874-3;O94874;O94874-2 O94874-3 UFL1 E3 UFM1-protein ligase 1 1 KDDDS(0.002)DDES(0.663)QS(0.264)S(0.069)HT(0.001)GK 88.574 0.012123 0.0 4011.7 4495.6 6326.5 4821.2 6771.0 5579.2 5271.2 5127.4 7972.6 5806.1 True False 3954.4924223443227 4485.19071440884 5806.359590996225 5175.767131051731 6372.743092298185 5340.590621750424 5544.116943820314 5365.6377224939715 7074.641832800104 6809.676648858055 0.5807166222800709 0.6586495872988304 0.8526630397303695 0.7600606310609004 0.9358363724020374 0.7842649360812178 0.8141527461146091 0.7879430990888179 1.0389100977337127 1.0 12.733370579497912 -3.522453635835399 0.29464077127826466 0.938904595245716 7.7338251762910485e-50 0.6267520615904201 0.08287448452736819 12.630950089593265 0.4999670282219772 0.09328919995383671 4.893450193641909 0.00030029379897044295 3.522453635835399 -0.938904595245716 KDDEENYLDLFSHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KDDEENYLDLFSHK 14 1 Q07666;Q07666-3;Q07666-2 Q07666 KHDRBS1 KH domain-containing, RNA-binding, signal transduction-associated protein 1 0 ; 113.35 8.636200000000001e-05 9848800.0 88929.0 98176.0 90398.0 108601.0 116476.0 97158.0 108860.0 106908.0 92870.0 77592.0 False True 103982.92327218752 107922.26445741973 92553.4311563239 102516.43805919249 93653.36392996195 92062.86344311618 98547.9927218511 104101.77827838913 94228.04805722137 91658.81538206618 1.1344563295821588 1.1774346418024473 1.0097602807818173 1.1184569387228922 1.0217605752330727 1.004408174591454 1.0751610994651022 1.1357530407136105 1.0280303936336699 1.0 16.483986019686043 -5.25317069998499 24.970152633898685 1.0548404045775976 1.1559454941441936 0.4575030530418649 0.04618069868331506 560.3172486442604 1692063.2035842398 0.011792215059970813 0.03012651268769118 5.582507304670102e-06 5.25317069998499 0.10110508956659592 KDDEVQVVR ddPTM_PC-9_AZD4547_30min_R2 1 KDDEVQVVR 9 1 J3QRI7;J3QQQ9;J3QQV1;E5RIT6;J3QRC4;Q9UNX3;P61254 J3QRI7 RPL26;RPL26L1 60S ribosomal protein L26-like 1;60S ribosomal protein L26 0 65.157 0.032836000000000004 4081200.0 28540.0 32966.0 34928.0 42009.0 33846.0 42187.0 27551.0 40810.0 32956.0 35171.0 False True 37615.12633112216 43621.61481473399 34464.83189845023 32324.474082580105 29147.067124486468 39549.04022095342 30002.98562664085 34503.752220506365 34697.98687899254 33939.67399521924 1.1082936841532613 1.2852691166355505 1.0154732748259447 0.9524096809867222 0.8587904270557266 1.16527460536375 0.8840092462546072 1.0166200248525246 1.0223429631021241 1.0 15.050685086806592 -5.375982258699135 5.879202384415999 0.9844939023102327 1.195097920199036 0.4697843259140567 0.08845835486223799 0.17453707012371555 7.745968131826486 0.022307290821895472 0.04731298097862464 4.207438157779515e-06 5.375982258699135 0.21060401788880323 KDDEVQVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KDDEVQVVR 9 1 J3QRI7;J3QQQ9;J3QQV1;E5RIT6;J3QRC4;Q9UNX3;P61254 J3QRI7 RPL26;RPL26L1 60S ribosomal protein L26-like 1;60S ribosomal protein L26 0 68.557 0.027042 4712100.0 32806.0 37133.0 29077.0 43475.0 46470.0 34650.0 41358.0 39429.0 29554.0 30043.0 False True 38359.40785196491 40819.31883655233 29770.305955136562 41039.23669785173 37364.537087686185 32832.89300216113 37440.27083400983 38394.030528478776 29986.171339325105 35489.55807974284 1.0808646240613562 1.1501782790541897 0.8388469050035655 1.1563749710728746 1.0528318499692326 0.9251423454861751 1.0549658226198213 1.081840197677575 0.844929409150377 1.0 15.11510698944752 -1.5228787452803376 0.30733517129240856 0.985511703851784 1.996104331205296 0.1032275452616318 0.10296351285337937 143.34097900569836 2.045975276410899 0.10073170377437118 80.30108207800356 0.029999999999999995 1.5228787452803376 1.010592627353512 KDDEVQVVR ddPTM_PC-9_Lapatinib_30min_R1 3 KDDEVQVVR 9 1 J3QRI7;J3QQQ9;J3QQV1;E5RIT6;J3QRC4;Q9UNX3;P61254 J3QRI7 RPL26;RPL26L1 60S ribosomal protein L26-like 1;60S ribosomal protein L26 0 ;; 69.27600000000001 0.025818999999999998 22532000.0 149572.0 156511.0 164043.0 180420.0 179791.0 157181.0 158368.0 170881.0 150719.0 137429.0 False True 147439.07585185437 156148.60839550747 150556.01776429234 193688.688663477 169216.04686270596 150458.735036807 166567.52013942474 178820.75509176007 133743.43907856903 161183.41953736803 0.9147285513301371 0.9687634673819951 0.9340664082969657 1.2016663327990327 1.0498353202109332 0.933462855352348 1.0334035635768881 1.1094240065449354 0.8297592858027346 1.0 17.298343820154486 -3.0131147771112845 11.017886802846292 1.004330835792394 0.9526389123439029 0.0 0.10131569682165167 0.0 0.0 0.023098280891743893 0.0 0.0009702535108159425 3.0131147771112845 -0.05169192344849105 KDDPVTNLNNAFEVAEK ddPTM_PC-9_AZD4547_30min_R2 1 KDDPVTNLNNAFEVAEK 17 1 O43707;K7EJH8 O43707 ACTN4 Alpha-actinin-4 0 109.77 0.00027605 13670000.0 53961.0 46230.0 58612.0 73159.0 77682.0 58574.0 48983.0 64089.0 52786.0 57120.0 False True 71119.47554147457 61172.94342307687 57834.766583599536 56293.32284528268 66897.19518892512 54911.3585204477 53342.39210735543 54185.51766870944 55576.1601952452 55120.246185974895 1.2902604843512222 1.109808965959264 1.0492472473447576 1.0212821375171266 1.2136592235675976 0.9962103277836892 0.9677458973492061 0.9830420112038017 1.0082712622097523 1.0 15.750294711178228 -1.5228787452803376 0.5754254141192098 1.012115669617836 14.729013333645955 0.6047142019445395 0.06453128854499837 114.86146545734375 0.968322411073189 0.032691844123701706 1965.4326005888533 0.029999999999999995 1.5228787452803376 13.716897664028119 KDDPVTNLNNAFEVAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KDDPVTNLNNAFEVAEK 17 1 O43707;K7EJH8 O43707 ACTN4 Alpha-actinin-4 0 188.71 1.1578e-08 11144000.0 55030.0 52183.0 54630.0 74087.0 80472.0 56864.0 65452.0 57725.0 50150.0 58377.0 False True 64345.492107956765 57363.38337456737 55932.58638542874 69936.14558329477 64704.089273085476 53881.95173664911 59251.912728555835 56209.779914693136 50883.34887552121 68960.28798792236 0.9330803856159384 0.8318321319164725 0.8110840023641537 1.014151008121418 0.9382804388000481 0.7813475452145145 0.8592178840513711 0.8151036133221726 0.7378645066626298 1.0 16.07347817888771 -6.756154792062354 24.99957490354754 0.8284326336349487 0.9023528345716494 0.13348612819160022 0.08307667313352281 256.626713110453 1214012.9524421515 0.027880558212789636 0.027100812896348858 1.7532554918194275e-07 6.756154792062354 0.07392020093670071 KDDPVTNLNNAFEVAEK ddPTM_PC-9_Lapatinib_30min_R1 2 KDDPVTNLNNAFEVAEK 17 1 O43707;K7EJH8 O43707 ACTN4 Alpha-actinin-4 0 ; 208.85 1.0206e-17 42204000.0 241727.0 221670.0 243162.0 239962.0 244210.0 198657.0 250593.0 209196.0 232233.0 228250.0 False True 238279.92865269678 221156.73673436412 223170.15899246442 257609.60596976528 229846.04793533284 190160.90320208538 263567.47937903414 218916.0098675452 206076.47401809515 267702.7083759922 0.8900915874113208 0.8261281257705708 0.8336492385389647 0.962297346681861 0.858586935222601 0.7103435910517638 0.984552905639079 0.817757919580233 0.7697959997052322 1.0 18.0302722093843 -10.664277693067527 4.995904473308487 1.000007622050644 0.8515566768024616 0.25062729211790213 0.07760247687336691 6.489065903622463e-06 1.1151335879424763e-06 0.0740079291600712 0.017948637938789234 2.16631849201687e-11 10.664277693067527 -0.14845094524818236 KDDS(ph)DDDGGGWITPSNIK ddPTM_PC-9_AZD4547_30min_R2 2 KDDSDDDGGGWITPSNIK 18 1 Q9ULX3 Q9ULX3 NOB1 RNA-binding protein NOB1 1 KDDS(1)DDDGGGWITPSNIK;KDDS(1)DDDGGGWITPSNIK 58.98 0.013806 6659500.0 18299.2 22114.6 23819.7 25352.0 21079.7 23049.3 24721.0 28724.0 22712.0 23360.0 True False 24117.96495299475 29262.711975426686 23503.83521448451 19507.48808449547 18153.14751710799 21608.023627298015 26921.121109077296 24285.36581185555 23912.50995253302 22542.17351023062 1.0699041484198037 1.2981317867217192 1.0426605581674475 0.8653774258122059 0.8052971249142991 0.9585599018431543 1.1942557844681356 1.0773302672359342 1.060789898617384 1.0 14.460339006029145 -5.471393923361161 8.972189751364901 0.9934193460570129 1.18128737829804 0.29893046910633647 0.11446469333597793 0.5682901014601197 94.50450190114478 0.033496975093867495 0.06942106015574714 3.377583362060186e-06 5.471393923361161 0.1878680322410271 KDDS(ph)DDDGGGWITPSNIK ddPTM_PC-9_Lapatinib_30min_R1 1 KDDSDDDGGGWITPSNIK 18 1 Q9ULX3 Q9ULX3 NOB1 RNA-binding protein NOB1 1 KDDS(1)DDDGGGWITPSNIK 80.844 0.0172 0.0 12873.0 16312.0 13947.0 16511.0 15636.0 14823.0 17028.0 18500.0 11613.0 14882.0 True False 12689.428659380917 16274.230566206288 12800.331496976894 17725.274019081367 14716.321221558768 14189.054844100683 17909.62652135612 19359.5775375704 10305.02164968863 17454.333870981478 0.7270073297083881 0.9323890952528897 0.7333612151339647 1.01552280081856 0.8431327904197613 0.8129244546932008 1.0260847909602315 1.1091559082501834 0.5903990221489425 1.0 14.091297678326702 -3.276539649517757 0.5749060954229614 0.91607471229619 2.723000706244627e-12 0.08728192155777403 0.14922966765732223 50.58967555709814 3.2438978523268536 0.07005942156751722 45.208246099174616 0.0005290056986950719 3.276539649517757 -0.9160747122934669 KDELSDWSLAGEDDRDSR ddPTM_PC-9_AZD4547_30min_R2 1 KDELSDWSLAGEDDRDSR 18 2 B4DXZ6;P51114;P51114-3;P51114-2;E7EU85;E9PFF5;H7C4S4 B4DXZ6 FXR1 Fragile X mental retardation syndrome-related protein 1 0 77.24 0.020343 5877400.0 19636.0 19870.0 22936.0 24010.0 25315.0 27122.0 20944.0 28142.0 22589.0 21388.0 False True 25879.839545827417 26292.588920972055 22631.853653883834 18474.86545080216 21800.44921870753 25426.057052473487 22807.975426095836 23793.30053882603 23783.008423642503 20639.212630000533 1.2539160291516773 1.2739143392880186 1.0965463682944405 0.8951342176662136 1.0562636089624398 1.2319296045002677 1.1050797254224154 1.1528201664166593 1.152321498402136 1.0 14.333100313660383 -5.267067186312378 14.955247790102291 1.0896948693250228 1.2639179118447517 0.3998932142215684 0.08697004322788869 1.9304345098112017 5140.387179204876 0.024598457196355186 0.05478973815424671 5.40670673531981e-06 5.267067186312378 0.17422304251972887 KDEWGLVAPIS(ph)PGPLTPMR ddPTM_PC-9_AZD4547_30min_R2 6 KDEWGLVAPISPGPLTPMR 19 1 A0A669KB77;P11137-3;P11137;E7EV03 A0A669KB77 MAP2 Microtubule-associated protein 2 1 KDEWGLVAPIS(0.999)PGPLT(0.001)PMR;KDEWGLVAPIS(0.624)PGPLT(0.376)PMR;KDEWGLVAPIS(0.991)PGPLT(0.009)PMR;KDEWGLVAPIS(0.974)PGPLT(0.026)PMR;KDEWGLVAPIS(1)PGPLTPMR;KDEWGLVAPIS(0.989)PGPLT(0.011)PMR 121.5 1.4143e-05 102470500.0 321020.0 320563.0 466080.0 590511.0 522668.0 485484.0 409686.0 482396.0 393180.0 426370.0 True False 423097.68236919487 424178.7207988702 459899.4746687375 454377.8122540036 450104.57010639686 455126.6087332434 446147.26033305394 407852.7825572998 413962.69210712117 411442.91607692855 1.0283265693413643 1.0309540016957308 1.1177722515041404 1.104352012148989 1.0939660218192688 1.1061719401389505 1.084347895905046 0.9912742852547801 1.0061242421043932 1.0 18.65033275829041 -7.758887297314329 24.964680602005416 0.9990244334068923 1.0827264815405446 0.6326715409265536 0.02850557991234543 45.04854303661838 440683.3826629697 0.015732394628540904 0.008535996670487024 1.7422589440358845e-08 7.758887297314329 0.08370204813365234 KDEWGLVAPIS(ph)PGPLTPMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KDEWGLVAPISPGPLTPMR 19 1 A0A669KB77;P11137-3;P11137;E7EV03 A0A669KB77 MAP2 Microtubule-associated protein 2 1 KDEWGLVAPIS(0.944)PGPLT(0.056)PMR;KDEWGLVAPIS(0.967)PGPLT(0.033)PMR;KDEWGLVAPIS(0.983)PGPLT(0.017)PMR 90.601 0.00045269 45720300.0 64016.0 69287.9 105687.0 143383.0 206067.0 206593.0 197314.0 177235.0 174559.0 148156.0 True False 74852.64442636682 76166.34480422155 108206.97890017925 135349.71536395812 165689.65061433715 195758.8993938088 178622.98949034844 172582.76904600536 177111.5951418164 175015.50999774932 0.4276914910417335 0.43519768508060247 0.618270797265744 0.7733584032963633 0.9467140976046517 1.1185231491559018 1.0206123416870054 0.9860998550826995 1.011976567928717 1.0 17.417123254810477 -5.827652254838088 1.296072572827005 1.0289760939952628 0.41253399361629334 0.9713382652838862 0.04095446428560721 0.07395067920483353 0.24949113173343154 0.015677131598315484 0.0360386472731884 1.4871259264886844e-06 5.827652254838088 -0.6164421003789695 down KDEWGLVAPIS(ph)PGPLTPMR ddPTM_PC-9_Lapatinib_30min_R1 6 KDEWGLVAPISPGPLTPMR 19 1 A0A669KB77;P11137-3;P11137;E7EV03 A0A669KB77 MAP2 Microtubule-associated protein 2 1 KDEWGLVAPIS(0.966)PGPLT(0.034)PMR;KDEWGLVAPIS(0.678)PGPLT(0.322)PMR;KDEWGLVAPIS(0.993)PGPLT(0.007)PMR;KDEWGLVAPIS(0.996)PGPLT(0.004)PMR;KDEWGLVAPIS(0.985)PGPLT(0.015)PMR;KDEWGLVAPIS(0.993)PGPLT(0.007)PMR 99.37799999999999 0.00018732 58856500.0 188510.6 209674.5 254548.7 231409.4 344774.0 355667.0 324532.8 345827.0 371461.0 260559.7 True False 185822.40427538982 209189.0115776124 233620.688472397 248428.01923512874 324495.0711717637 340455.9515102716 341335.5204328141 361895.38492353325 329623.15052225813 305597.0969710231 0.6080633818750236 0.6845255195518034 0.7644728657044445 0.8129266334577938 1.061839508254663 1.1140680159751448 1.116946213874472 1.184223896465379 1.0786200320270491 1.0 18.221271312949867 -6.063129825898279 1.3654879779263913 1.1185612162274445 0.6529359314115961 0.9262475528056983 0.05302693192897332 0.098685631240169 0.37246086149943164 0.018844030483915426 0.0320722820906563 8.64709388080762e-07 6.063129825898279 -0.4656252848158484 KDEWGLVAPISPGPLT(ph)PMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KDEWGLVAPISPGPLTPMR 19 1 A0A669KB77;P11137-3;P11137;E7EV03 A0A669KB77 MAP2 Microtubule-associated protein 2 1 KDEWGLVAPIS(0.444)PGPLT(0.556)PMR 100.07 0.00021562 33736000.0 19323.0 25883.0 37382.0 41657.0 65475.0 54932.0 55962.0 53601.0 60698.0 48175.0 True False 22594.0022533536 28452.493185212184 38273.32865202448 39323.09334381618 52645.64376622021 52051.26921774071 50660.874230205976 52194.030544953996 61585.593420665726 56908.7461469098 0.3970216141298779 0.499966966619896 0.672538603349685 0.6909850595250105 0.9250888014702625 0.914644456993842 0.8902124481784407 0.917153057813209 1.0821815202479186 1.0 15.796362772909243 -5.047264753343388 0.46869438134073166 1.008546609486504 0.040388476315337034 0.941200939990975 0.051485246940964874 0.8556988510587673 0.174954904448313 0.03765244869725231 0.44746396076978157 8.9688187328317e-06 5.047264753343388 -0.9681581331711671 down KDKS(ph)PVREPIDNLTPEER ddPTM_PC-9_AZD4547_30min_R2 1 KDKSPVREPIDNLTPEER 18 3 G3XAC6;Q14498-2;Q14498;Q5QP23;Q5QP22;H0Y4X3;Q14498-3 G3XAC6 RBM39 RNA-binding protein 39 1 KDKS(1)PVREPIDNLTPEER 59.501999999999995 0.02369 54648000.0 93678.0 127800.0 134720.0 209180.0 154110.0 146920.0 113550.0 189230.0 139420.0 141500.0 True False 123465.65537655442 169108.85073478761 132933.52477551578 160956.78279878382 132714.4866322343 137733.06917444922 123655.73002450237 159988.85157281146 146789.45656842884 136546.12806924817 0.9042047337581034 1.2384741561403012 0.9735429825450613 1.1787722220666412 0.9719388495946902 1.0086926017015958 0.9055967516104994 1.1716835463227087 1.0750173486719876 1.0 17.059028879755736 -4.500688999216198 18.877713684442057 1.0565903761277669 0.5044144699294132 0.17016971284623617 0.10195812707326012 14820764.598941168 314954043.1496796 0.024534768008811315 251120997.40505236 3.157264749533781e-05 4.500688999216198 -0.5521759061983537 KDLYANTVLSGGT(ph)TMYPGIADR ddPTM_PC-9_AZD4547_30min_R2 1 KDLYANTVLSGGTTMYPGIADR 22 1 P60709;A0A2R8Y793;P63261 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 KDLYANTVLS(0.011)GGT(0.456)T(0.456)MY(0.076)PGIADR 66.556 0.00125 3114000.0 14707.0 15373.0 14743.0 18841.0 20062.0 16672.0 16073.0 23073.0 14449.0 15471.0 True False 19383.5200753964 20342.02161460006 14547.498187094925 14497.498540548253 17276.737595327293 15629.497204440591 17503.46586247318 19507.598014794006 15212.744641781866 14929.364999005911 1.2983485953144742 1.3625510271839798 0.974421764627202 0.9710726840367012 1.1572319115031138 1.0468963151132884 1.1724186436354571 1.3066595944363972 1.0189813594077728 1.0 13.86586518318214 -5.248073647598793 24.703039655072324 1.092761641138596 1.3304498525986945 0.4881006699279574 0.10162646982961754 615.1348153591601 1136908.9943026123 0.02729670286266111 0.07126940790712473 5.648411810000253e-06 5.248073647598793 0.23768821146009844 KDLYANTVLSGGTT(ph)MYPGIADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KDLYANTVLSGGTTMYPGIADR 22 1 P60709;A0A2R8Y793;P63261 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 KDLYANTVLS(0.001)GGT(0.168)T(0.452)MY(0.379)PGIADR;KDLYANTVLSGGT(0.221)T(0.603)MY(0.176)PGIADR 84.37100000000001 0.00077279 0.0 19260.8 20436.5 22173.0 26663.0 30972.0 24781.0 25438.0 32489.0 26002.4 16422.0 True False 22521.27302185961 22465.3006598767 22701.688411570776 25169.158552612327 24903.25893436231 23481.44073554274 23028.328484828617 31636.19817494094 26382.635908292177 19399.178603519533 1.1609395161593927 1.1580542206978233 1.170239672284479 1.2974342402335513 1.2837274940004002 1.2104347929083232 1.1870775023768614 1.6308009128387158 1.3599872678890466 1.0 14.24370794692491 -5.886871782465354 0.7530063915132926 1.3235720264110813 1.1336247382816107 0.07619603128775243 0.15230336232851083 1.8699551146658075 1.9836691411204335 0.07959703196680963 0.23537235555345273 1.2975622960720216e-06 5.886871782465354 -0.1899472881294706 KDLYANTVLSGGTTMYPGIADR ddPTM_PC-9_AZD4547_30min_R2 1 KDLYANTVLSGGTTMYPGIADR 22 1 P60709;A0A2R8Y793;P63261 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 93.416 0.00017491 8182600.0 80585.0 78331.0 102090.0 127040.0 115410.0 92187.0 91987.0 107710.0 90488.0 93464.0 False True 106209.35372787263 103649.96390380783 100736.21989557886 97752.8907484342 99387.31362160922 86422.53231680443 100173.6647975685 91065.8944295699 95271.01094508659 90191.8538082276 1.1775936433649825 1.1492164705273253 1.1169104042341944 1.083832814394562 1.1019544385120819 0.958207739033308 1.110673088176732 1.0096909042716955 1.0563150320389094 1.0 16.46070951368197 -5.422503827802659 0.5947726883533968 1.0280956016528808 1.2193137348962129 0.6148177076422652 0.041039718245437964 1.3000576092708098 0.5834817279276229 0.022880332463079557 0.15508783551321983 3.780038056215593e-06 5.422503827802659 0.19121813324333203 KDLYANTVLSGGTTMYPGIADR ddPTM_PC-9_Lapatinib_30min_R1 3 KDLYANTVLSGGTTMYPGIADR 22 1 P60709;A0A2R8Y793;P63261 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ;; 153.6 5.493999999999999e-06 37269600.0 200858.0 179250.0 202186.0 189618.0 206056.0 210782.0 182315.0 170062.0 192353.0 182607.0 False True 197993.728087154 178834.95763808727 185563.0475405296 203563.140267105 193936.19120168267 201767.34521684053 191754.3786258537 177963.70136185442 170688.17957311243 214170.3766414676 0.9244683190645262 0.835012574766427 0.866427236345444 0.9504729060073529 0.9055229497324085 0.9420880160033038 0.89533567448901 0.8309445225460613 0.7969738030523865 1.0 17.708399419380406 -10.12952245053942 8.716986050290647 0.9999983429235981 0.8843394679275303 0.3471786867193196 0.04808978853571976 0.0 0.0 0.04993346513621217 0.012110644177041162 7.421258330885966e-11 10.12952245053942 -0.11565887499606786 KDMS(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 1 KDMSPQK 7 1 J3QT87;A0A1W2PPJ5;Q96SW2-2;Q96SW2 J3QT87 CRBN Protein cereblon 1 KDMS(1)PQK 57.59 0.039681 6336700.0 3690.1 9647.7 48477.0 84725.0 55246.0 30902.0 15250.0 64033.0 16117.0 28521.0 True False 4863.475041151851 12766.130353943729 47834.163305690876 65192.96023820125 47576.04651537491 28969.69305491981 16607.220456835443 54138.17118195746 16968.911716492377 27522.488471116747 0.1767091317435117 0.46384360801317226 1.7380028465045976 2.368716052206452 1.7286244507034023 1.052582621128966 0.6034054832746594 1.9670521885683532 0.6165471459566697 1.0 14.74832329808631 -5.1537289639187716 5.000542539921118 1.4245617193113445 0.2541172225026511 0.374640532384629 0.5514176744614986 0.23054955012475958 8.633963270504342 0.14842709724411446 0.4216788825455517 7.0189320182608e-06 5.1537289639187716 -1.1704444968086933 KDNDFIYHDR ddPTM_PC-9_AZD4547_30min_R2 2 KDNDFIYHDR 10 1 Q8WUM4;Q8WUM4-2 Q8WUM4 PDCD6IP Programmed cell death 6-interacting protein 0 ; 87.667 0.0041586 28357000.0 111097.0 105537.0 153630.0 183318.0 154625.0 143531.0 131310.0 167199.0 133588.0 139888.0 False True 146423.5350388468 139649.77136148093 151592.7658199413 141056.8673348667 133157.9877717813 134555.983880192 142996.33561882348 141362.23640079508 140649.18895469283 134990.5636985935 1.0846945966221817 1.0345150619067751 1.1229878716442516 1.0449387236415875 0.9864244145916454 0.9967806652072969 1.0593061596372413 1.0472008748435797 1.041918672691329 1.0 17.042499035927328 -5.992306761359648 24.973900671227074 1.0240701433639359 1.0774195308638757 0.4380054585382277 0.029676016604224524 192.89276638115945 626162.0445271601 0.008677903639671084 0.012846658795160143 1.01787216604142e-06 5.992306761359648 0.05334938749993978 KDNDFIYHDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KDNDFIYHDR 10 1 Q8WUM4;Q8WUM4-2 Q8WUM4 PDCD6IP Programmed cell death 6-interacting protein 0 ; 92.866 0.0028406 19672000.0 174014.0 178154.0 197843.0 211410.0 226280.0 195044.0 211682.0 187805.0 178970.0 152274.0 False True 203471.1332668365 195839.95174123102 202560.3274437554 199565.38310046736 181942.0583645714 184815.54928466128 191629.94851503582 182875.317745846 181587.09767202503 179880.07079967935 1.1311488391253135 1.0887251204127284 1.126085433162485 1.1094357602444478 1.0114631240455112 1.0274376058617314 1.065320619805857 1.0166513551659775 1.0094898054284551 1.0 17.456675831392303 -6.254372665660844 24.15195592786585 1.0250248548126084 1.1129282971082715 0.8404225130728865 0.019632313911941517 139.26735367753147 475974.34521666344 0.005914940867045201 0.007462621801523464 5.567078360401257e-07 6.254372665660844 0.08790344229566305 KDNDFIYHDR ddPTM_PC-9_Lapatinib_30min_R1 2 KDNDFIYHDR 10 1 Q8WUM4;Q8WUM4-2 Q8WUM4 PDCD6IP Programmed cell death 6-interacting protein 0 ; 71.555 0.013040000000000001 27416000.0 337310.0 379900.0 429840.0 385260.0 447740.0 405110.0 367160.0 385710.0 433770.0 334900.0 False True 332499.8975449212 379020.3648909867 394500.2144303838 413593.3055896853 421404.8134907084 387784.3896575337 386169.74827232247 403631.49470358255 384914.25479940017 392787.01877379965 0.8465144764277536 0.9649513521964407 1.0043616402139064 1.052970912533817 1.072858300679711 0.9872637615879387 0.9831530315789586 1.0276090486993108 0.9799566594665561 1.0 18.58338772521943 -4.747186253728589 1.9888167445396423 1.0161507900224958 0.7864826618324918 0.754983254839733 0.02881333150798448 0.43165022159326066 1.7325079111695134 0.00838530152574546 0.18907569100442898 1.7898380903953883e-05 4.747186253728589 -0.22966812819000393 KDPSGASNPS(ph)ADSPLHR ddPTM_PC-9_Lapatinib_30min_R1 1 KDPSGASNPSADSPLHR 17 1 P55317-2;P55317 P55317-2 FOXA1 Hepatocyte nuclear factor 3-alpha 1 KDPSGAS(0.001)NPS(0.728)ADS(0.271)PLHR 120.25 4.0335e-05 11030000.0 41492.0 45176.0 45377.0 28092.0 40838.0 43743.0 33200.0 39448.0 38968.0 25902.0 True False 40900.316471299106 45071.39774760519 41646.27822028543 30157.979392164838 38435.989130597176 41872.21385991337 34918.933551152375 41280.89809200419 34579.01348876833 30379.12618775448 1.3463295888933637 1.4836304859147995 1.370884664782512 0.9927204359262057 1.265210490026877 1.3783218648596824 1.1494383786860811 1.358857323178838 1.1382491147064917 1.0 14.890792752920603 -9.864975358223298 0.03758825603987456 2.7542717811052116e-13 2.231117883864719 0.36215382957929976 0.12835479568774577 337.13559831530137 3.2197780138101844 111.47460039726715 80.06710735247117 1.364660564943007e-10 9.864975358223298 2.2311178838644437 KDPSGASNPSADS(ph)PLHR ddPTM_PC-9_AZD4547_30min_R2 2 KDPSGASNPSADSPLHR 17 1 P55317-2;P55317 P55317-2 FOXA1 Hepatocyte nuclear factor 3-alpha 1 KDPSGASNPS(0.258)ADS(0.742)PLHR;KDPSGASNPS(0.352)ADS(0.648)PLHR 132.67 1.0793e-05 20304000.0 33792.0 35171.0 47709.0 73091.0 66134.0 52774.0 34507.0 54507.0 42803.0 50597.0 True False 44537.15308273582 46539.33794360884 47076.3474874932 56240.99919469315 56952.435655935355 49474.03343732894 37578.056151083314 46084.1955962544 45065.479195943626 48825.614430528185 0.9121677955759425 0.953174649954024 0.9641731709178194 1.1518748888396682 1.1664458567535378 1.0132803040855403 0.7696381620461014 0.9438528553865015 0.9229884707352799 1.0 15.575350578915964 -7.0289514346413045 24.691667572954373 0.902586385403424 1.034622901807859 0.2761369487593385 0.0932745218707899 822.9362165669522 701851.1126217864 0.038601995522447814 0.02996013046858757 9.35510282550626e-08 7.0289514346413045 0.13203651640443503 KDPSGASNPSADS(ph)PLHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KDPSGASNPSADSPLHR 17 1 P55317-2;P55317 P55317-2 FOXA1 Hepatocyte nuclear factor 3-alpha 1 KDPSGASNPS(0.071)ADS(0.929)PLHR;KDPSGASNPS(0.247)ADS(0.753)PLHR 101.0 0.00050622 18067400.0 33914.0 37143.0 44174.0 47636.0 55751.0 41489.0 48826.0 39426.0 37594.0 35978.0 True False 39654.97036796742 40830.311570464626 45227.275690827904 44967.109357995716 44826.991761902136 39313.24380278974 44200.84781037197 38391.10927530002 38143.74112913945 42500.5265983087 0.933046565346451 0.9607013098065815 1.0641580072240262 1.0580365223000594 1.0547396785357952 0.9250060399099667 1.0400070622214581 0.9033090257481136 0.8974886708970183 1.0 15.375193096471833 -7.766386656076419 24.999966417975084 0.9252991236921578 1.0065279672740302 0.25697826467224005 0.05513820043279699 163.1345709747135 824343.3542371176 0.030101858863640783 0.01517170802024412 1.7124320358005623e-08 7.766386656076419 0.08122884358187232 KDPSGASNPSADS(ph)PLHR ddPTM_PC-9_Lapatinib_30min_R1 1 KDPSGASNPSADSPLHR 17 1 P55317-2;P55317 P55317-2 FOXA1 Hepatocyte nuclear factor 3-alpha 1 KDPSGASNPS(0.006)ADS(0.994)PLHR 146.72 4.04e-05 14228000.0 47974.0 37772.0 48311.0 41486.0 36545.0 41354.0 37664.0 34311.0 46495.0 29166.0 True False 47289.88196264588 37684.541254704774 44339.056065852936 44537.01883323903 34395.49495023441 39585.38582088238 39614.05762863265 35905.2143184637 41258.24348594444 34207.30423874785 1.382449830965602 1.1016518867341243 1.2961867955566193 1.3019739445819978 1.0055014774088333 1.1572202692325162 1.1580584471710687 1.0496358926112794 1.2061237915149636 1.0 15.06201679424773 -1.5228787455411363 0.14676828392439126 0.9997886236558284 2.0732860097971484 0.3883668686740741 0.09737790431870195 79.39093497681252 0.7706463697187622 0.364170095468696 18.049685900650644 0.02999999998198466 1.5228787455411363 1.07349738614132 KDQGELER ddPTM_PC-9_AZD4547_30min_R2 1 KDQGELER 8 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 69.812 0.025214 2885400.0 24825.0 15801.0 21747.0 32231.0 31197.0 31304.0 25290.0 24125.0 27088.0 38210.0 False True 32718.833607922475 20908.364244603894 21458.62057076263 24800.640913986044 26865.83504941808 29346.555931370473 27540.76100677824 20397.03558734908 28519.81637875197 36872.27953021885 0.8873558680066851 0.5670483222353623 0.581971628664187 0.6726093756601232 0.7286187724683542 0.795897522617753 0.7469231996955078 0.5531807592918846 0.7734758127817516 1.0 15.17024898950664 -8.541611653583049 22.63301141142103 1.000000004798748 0.6881419240447676 0.4616345070056408 0.1003905604087094 974.1602585723539 1176975.7222864912 0.09767746769577204 0.025220213699106753 2.8733487840190995e-09 8.541611653583049 -0.31185808075398047 KDQGELER ddPTM_PC-9_Lapatinib_30min_R1 1 KDQGELER 8 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 60.019 0.045211 3142100.0 22683.0 20640.0 23257.0 24965.0 21189.0 20642.0 19337.0 21529.0 24373.0 20081.0 False True 22359.53626044725 20592.20934811781 21344.899234616176 26801.009380798638 19942.704679176823 19759.18977885222 20338.17524333235 22529.315935478557 21627.8560809318 23551.974093749417 0.9493699411966221 0.8743305026640159 0.9062891776991642 1.1379517179373724 0.8467529982749735 0.8389610866673046 0.8635443959973617 0.9565786649475694 0.9183033233155488 1.0 14.523560369149752 -9.205351728253305 1.4976030399055622 0.9999902486546921 0.9198967330645501 0.07616891057708819 0.08192561021787163 19.198575198609866 38.96453164083774 0.08266790676951376 0.02372048374725253 6.232298869762028e-10 9.205351728253305 -0.080093515590142 KDS(ph)FFS(ph)NIS(ph)RS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 KDSFFSNISRSR 12 2 Q92609;Q92609-2;C9J3F6 Q92609 TBC1D5 TBC1 domain family member 5 4 KDS(1)FFS(1)NIS(1)RS(1)R 51.265 0.039398 3625600.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KDS(ph)FQENEDGYR ddPTM_PC-9_Lapatinib_30min_R1 1 KDSFQENEDGYR 12 1 Q5VYS8-5;Q5VYS8-3;Q5VYS8-2;Q5VYS8-4;Q5VYS8-6;Q5VYS8 Q5VYS8-5 ZCCHC6 Terminal uridylyltransferase 7 1 KDS(0.992)FQENEDGY(0.008)R 100.18 0.0045727 3177000.0 7184.1 8353.9 8280.0 7955.9 9387.7 11364.0 11645.0 12697.0 11878.0 13378.0 True False 7081.653416597412 8334.55705781209 7599.250361724295 8541.003426104382 8835.533942928327 10877.988210777856 12247.921120577392 13286.948972677372 10540.174559114916 15690.369474935496 0.4513375818147536 0.5311893433182747 0.48432577536581783 0.5443468644730238 0.56311828456574 0.6932907620916667 0.7806011923519566 0.8468219307328959 0.6717607622913065 1.0 13.937591704664966 -7.212178321028266 0.2864409895787217 1.014652235174567 0.3605853049108974 0.858862533952398 0.06285685620756143 0.7465749799569041 0.16746606026299063 0.1072384221942416 0.17620013666939885 6.13510046620211e-08 7.212178321028266 -0.6540669302636697 down KDS(ph)ISEDEMVLR ddPTM_PC-9_AZD4547_30min_R2 2 KDSISEDEMVLR 12 1 Q8N5D0-5;Q8N5D0-3;Q8N5D0-6;Q8N5D0-2;Q8N5D0-4;Q8N5D0 Q8N5D0-5 WDTC1 WD and tetratricopeptide repeats protein 1 1 KDS(0.967)IS(0.033)EDEMVLR;KDS(0.665)IS(0.335)EDEMVLR 72.898 0.023027000000000002 19204400.0 106654.0 93503.0 108135.0 129312.0 143425.0 145245.0 113007.0 128378.0 122318.0 141970.0 True False 140567.7534589875 123726.01619917706 106701.05924584613 99501.11625048443 123512.9144457092 136162.80718923788 123064.40407643311 108540.12993296159 128783.4797628537 136999.67351230464 1.026044441239945 0.9031117595186429 0.7788417045845205 0.7262872509075557 0.9015562685601282 0.993891472135577 0.8982824624423654 0.7922656102039035 0.9400276399292806 1.0 17.063812929500422 -6.498664151686923 24.63352166718544 0.9144109836600817 0.850790782070521 0.09735088713360074 0.09143718666650358 1706.56167119662 1736087.513266744 0.030542181279174137 0.03443827944577689 3.1720194987772676e-07 6.498664151686923 -0.06362020158956072 KDS(ph)LESDSSTAIIPHELIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KDSLESDSSTAIIPHELIR 19 1 Q9UMX1-2;Q9UMX1-3;Q9UMX1 Q9UMX1-2 SUFU Suppressor of fused homolog 1 KDS(0.786)LES(0.212)DS(0.001)STAIIPHELIR 63.184 0.006220300000000001 3840100.0 13929.0 14047.0 13999.0 14860.0 17981.0 13115.0 15697.0 11768.0 13912.0 13300.0 True False 16286.90458970979 15441.493326611126 14332.789251503142 14027.442376770023 14457.752127688525 12427.226312362005 14210.0665235614 11459.102469226656 14115.436681081776 15711.184717257927 1.0366439503330047 0.9828344332079197 0.9122666119353374 0.8928316119510453 0.920220364528426 0.7909795814895701 0.9044554423672693 0.7293595406996535 0.8984323547273106 1.0 13.939504352114712 -4.9627790122052495 0.7945252651215898 0.855569691845703 1.115910869479013 0.3649052790834705 0.06979701389070012 1.9725479119073694 1.1406131330095448 0.02629245103707211 0.43363146839774913 1.0894843290063675e-05 4.9627790122052495 0.26034117763331 KDS(ph)LESDSSTAIIPHELIR ddPTM_PC-9_Lapatinib_30min_R1 2 KDSLESDSSTAIIPHELIR 19 1 Q9UMX1-2;Q9UMX1-3;Q9UMX1 Q9UMX1-2 SUFU Suppressor of fused homolog 1 KDS(0.999)LES(0.001)DSSTAIIPHELIR;KDS(0.922)LES(0.077)DSSTAIIPHELIR 119.28 2.3404e-05 10750900.0 43789.0 56993.0 54069.0 46339.0 52789.0 56331.0 55269.0 52882.0 56505.0 50818.0 True False 43164.56083008091 56861.03621013946 49623.65553237572 49746.92464237243 49684.054807167195 53921.854443974626 58130.558386706056 55339.09077523233 50140.81187597142 59601.82358927135 0.7242154389022883 0.9540150415863241 0.8325861952537346 0.8346544056300846 0.833599574898084 0.9047014201370989 0.9753150975261413 0.9284798256607986 0.8412630496258345 1.0 15.863068851897129 -6.880541058212595 4.324553160827921 0.9314544419289333 0.8422692373440048 0.35202960816301754 0.06443108754757657 0.2761475501801741 9.08742981630921 0.022612168106010876 0.019900902915666947 1.3166154339772568e-07 6.880541058212595 -0.08918520458492851 KDS(ph)LPDADLASCGSLSQSSASFFTPR ddPTM_PC-9_AZD4547_30min_R2 2 KDSLPDADLASCGSLSQSSASFFTPR 26 1 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 KDS(1)LPDADLASCGSLSQSSASFFTPR;KDS(1)LPDADLASCGSLSQSSASFFTPR 107.95 3.0239999999999996e-10 41353000.0 129243.0 114967.0 153987.0 169187.0 164881.0 146208.0 138878.0 165874.0 156583.0 150884.0 True False 170339.5855785995 152127.83444778027 151945.0317666815 130183.55106309307 141990.11920322798 137065.59064700402 151237.8729576654 140241.98470532373 164859.6577094698 145601.59708551544 1.1699019034698832 1.0448225671482971 1.0435670680002254 0.8941079882979102 0.9751961657387154 0.9413742252188483 1.0387102613224746 0.9631898791807628 1.132265449070889 1.0 17.15166665479977 -4.705916937214983 1.6277969159061128 0.9913597153437923 1.2564344386095219 0.41808616507096275 0.061150624420461284 1.1789173377211897 2.64021042894257 0.016954001607710514 0.5263502315283589 1.968262701922649e-05 4.705916937214983 0.26507472326572956 KDS(ph)LPDADLASCGSLSQSSASFFTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 KDSLPDADLASCGSLSQSSASFFTPR 26 1 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 KDS(0.999)LPDADLAS(0.001)CGSLSQSSASFFTPR;KDS(0.998)LPDADLAS(0.001)CGS(0.001)LSQSSASFFTPR;KDS(1)LPDADLASCGSLSQSSASFFTPR;KDS(1)LPDADLASCGSLSQSSASFFTPR;KDS(1)LPDADLASCGSLSQSSASFFTPR;KDS(1)LPDADLASCGSLSQSSASFFTPR 119.35 1.3127e-10 38948800.0 137514.3 139384.2 135326.1 155818.9 178314.1 143854.6 164025.0 168526.59999999998 137171.3 110801.7 True False 160792.7549587716 153221.34221791313 138552.78745109247 147088.87220468975 143374.73214347757 136310.61153445014 148487.36456183714 164102.95531869296 139177.17075989587 130889.17110422536 1.2284649188490497 1.1706189360455568 1.058550423096229 1.1237665496984832 1.0953903285804303 1.0414200837585545 1.1344511032436637 1.2537550198711236 1.0633207436929284 1.0 16.997986217705623 -10.426080974439607 0.012750542504989124 4.919474307141223e-07 2.1302076335527733 0.23953388290465083 0.06783931741448802 6131.077531677421 15.449968038565482 1386.3647057852688 1198.2878589292181 3.749030948449858e-11 10.426080974439607 2.1302071416053425 KDS(ph)LPDADLASCGSLSQSSASFFTPR ddPTM_PC-9_Lapatinib_30min_R1 5 KDSLPDADLASCGSLSQSSASFFTPR 26 1 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 KDS(1)LPDADLASCGSLSQSSASFFTPR;KDS(0.987)LPDADLAS(0.01)CGS(0.001)LSQSSASFFTPR;KDS(0.957)LPDADLAS(0.037)CGS(0.005)LSQSSASFFTPR;KDS(0.823)LPDADLAS(0.166)CGS(0.008)LS(0.001)QS(0.001)SASFFTPR;KDS(0.999)LPDADLASCGSLSQSSASFFTPR 84.646 6.4443e-07 46930300.0 117198.0 116733.0 138553.0 127816.0 158189.0 130589.0 107546.0 108316.0 135918.0 111881.0 True False 115526.73502851912 116462.71191055393 127161.7071700468 137216.01502167678 148884.6340315399 125004.01288782732 113114.20565338056 113348.75678699887 120609.48356000855 131219.48177793858 0.8804084078309642 0.8875413188084572 0.9690764316935901 1.0456984981383028 1.1346229387149682 0.9526330327944015 0.8620229566582392 0.8638104285369596 0.9191431175144769 1.0 17.00162240306574 -7.007057050131718 24.95740654386929 0.9009568407935873 0.987080739972086 0.15650518152733484 0.07736405575779237 570.6921883754037 2018269.2999693311 0.031000090645268777 0.026290911926398326 9.838818518136934e-08 7.007057050131718 0.08612389917849872 KDS(ph)LSQLEEYLR ddPTM_PC-9_AZD4547_30min_R2 3 KDSLSQLEEYLR 12 1 O60303 O60303 KIAA0556 Uncharacterized protein KIAA0556 1 KDS(0.987)LS(0.013)QLEEYLR;KDS(0.997)LS(0.003)QLEEYLR;KDS(0.962)LS(0.038)QLEEYLR 111.81 0.00047165 13508500.0 20151.4 18061.7 19095.2 31834.1 30692.1 25461.8 20539.9 24887.4 18154.2 26867.2 True False 26559.126024841444 23899.79130920588 18841.985171417975 24495.24007694216 26431.03169920967 23869.669620922836 22367.911308941257 21041.624185558212 19113.793949466144 25926.587505739233 1.024397291736222 0.9218255701378096 0.7267437400794464 0.94479229368384 1.0194566366807345 0.9206637632368291 0.8627402778707298 0.8115847942156035 0.7372275254209611 1.0 14.662144708666558 -7.40106777729917 3.5693275607880244 0.831729389159268 0.9219796236584297 0.1099777672603579 0.09816857703628812 0.5171844818758845 11.955073614974832 0.04642752001756831 0.029491627993744426 3.9712956740184623e-08 7.40106777729917 0.0902502344991617 KDS(ph)LSQLEEYLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KDSLSQLEEYLR 12 1 O60303 O60303 KIAA0556 Uncharacterized protein KIAA0556 1 KDS(0.985)LS(0.015)QLEEYLR;KDS(0.96)LS(0.04)QLEEYLR 86.49799999999999 0.004166899999999999 8959800.0 10593.9 15144.8 13651.2 15461.3 18124.3 14463.7 13618.4 17053.6 13422.0 10068.9 True False 12387.23803093737 16648.27565550368 13976.696380464295 14595.053487210922 14572.973521376185 13705.198110111358 12328.36656332219 16605.961069782777 13618.271358070695 11894.31186463146 1.0414421760515342 1.3996838022221743 1.175073979859646 1.2270616117448796 1.2252052651074257 1.1522480885056234 1.0364926280419315 1.396126254193967 1.144939826116847 1.0 13.53798418782355 -6.755825139218938 24.00900904902354 1.1638774522792836 1.222623342749804 0.05457268822184447 0.12805484183737045 308.6526825381697 1319933.212606199 0.04157445369392333 0.04041795475211205 1.7545868121359594e-07 6.755825139218938 0.05874589047052048 KDS(ph)LSQLEEYLR ddPTM_PC-9_Lapatinib_30min_R1 2 KDSLSQLEEYLR 12 1 O60303 O60303 KIAA0556 Uncharacterized protein KIAA0556 1 KDS(0.995)LS(0.005)QLEEYLR;KDS(0.983)LS(0.017)QLEEYLR 132.24 0.00013639 5951200.0 13970.7 13539.9 12266.6 14880.0 10531.3 14164.900000000001 11129.7 8435.6 13708.0 13517.6 True False 13771.475256087395 13508.549193438976 11258.08749844532 15974.324838224875 9911.86963933243 13559.10024699466 11705.941407959659 8827.548771671833 12164.060688360605 15854.099148930192 0.8686381437835697 0.852054037668265 0.7101057835383221 1.007583255798094 0.6251928631341546 0.8552425539681077 0.7383542450439107 0.55679914000459 0.7672501965639225 1.0 13.952568283462705 -6.27680212569309 24.991983194996404 0.7389456584224563 0.8483788383959112 0.11572522797891782 0.13171269453980375 1623.9638400357858 2641843.555150432 0.03937587634849803 0.044806230310774575 5.286860781433689e-07 6.27680212569309 0.10943317997345492 KDS(ph)LSVNEFK ddPTM_PC-9_AZD4547_30min_R2 2 KDSLSVNEFK 10 1 Q99584 Q99584 S100A13 Protein S100-A13 1 KDS(0.929)LS(0.071)VNEFK;KDS(0.952)LS(0.048)VNEFK 71.513 0.015115 16414900.0 77946.0 67904.0 78734.0 84450.0 90757.0 85364.0 80179.0 73237.0 85770.0 86948.0 True False 102731.20662248229 89852.64006490621 77689.93571611821 64981.357239493605 78156.95712985343 80026.1755854049 87314.77567269575 61919.90446883666 90303.62709707448 83903.97698491167 1.2243901935775499 1.0708984638602326 0.9259386564011034 0.7744729102790814 0.9315047979657541 0.9537828653795026 1.0406512159536543 0.7379853338772205 1.076273501473162 1.0 16.35645157448665 -4.980972484330892 2.4727048210914995 0.9201376836154754 1.2351650391828164 0.459780370709827 0.10069706974173445 0.3012393824428212 3.112664333525942 0.0259306913422957 0.1687285767409223 1.0447864118336873e-05 4.980972484330892 0.31502735556734096 KDS(ph)LTQAQEQGNLLN ddPTM_PC-9_AZD4547_30min_R2 3 KDSLTQAQEQGNLLN 15 1 Q5JTD0-4;Q5JTD0-2;Q5JTD0 Q5JTD0-4 TJAP1 Tight junction-associated protein 1 1 KDS(0.778)LT(0.222)QAQEQGNLLN;KDS(0.776)LT(0.224)QAQEQGNLLN;KDS(0.745)LT(0.255)QAQEQGNLLN 81.71300000000001 0.012544 307742000.0 215550.0 201998.0 228749.0 351746.0 328235.0 259047.0 241984.0 292866.0 250154.0 279797.0 True False 284090.4162814779 267289.90321381524 225715.6387980587 270656.3941215266 282665.2359985177 242848.75013907897 263520.1072148769 247610.2890911745 263376.6297404872 270001.39219357836 1.0521813016349129 0.9899575000049663 0.8359795368619105 1.0024259205577675 1.046902883359431 0.8994351775970392 0.975995364594066 0.9170704161171491 0.9754639692807898 1.0 18.042607320622523 -6.787519364409839 24.999822251752416 0.9498100862076223 0.978372578090675 0.05434697432198177 0.06213294831402727 876.8066423531658 840485.3420326122 0.022701212647008827 0.020026740194782098 1.631100179783045e-07 6.787519364409839 0.02856249188305271 KDS(ph)LTQAQEQGNLLN ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KDSLTQAQEQGNLLN 15 1 Q5JTD0-4;Q5JTD0-2;Q5JTD0 Q5JTD0-4 TJAP1 Tight junction-associated protein 1 1 KDS(0.787)LT(0.213)QAQEQGNLLN;KDS(0.864)LT(0.136)QAQEQGNLLN 97.291 0.0036414 115072000.0 97739.0 86569.0 89109.0 100336.0 127169.0 99194.0 104696.0 108395.0 86401.0 68905.0 True False 114284.28226675601 95162.99820541043 91233.69650776421 94714.49921370122 102251.14734030486 93992.09201894287 94778.43694660028 105549.74610399568 87664.4511703672 81396.93104832016 1.4040367467775012 1.169122680422905 1.1208493407890845 1.1636126570604397 1.2562039627710888 1.1547375411874654 1.1643981625097928 1.2967288169788311 1.0769994647381291 1.0 16.312686780369773 -14.52287874486605 0.16043042237066046 0.2592417425398343 1.2513646532373648 0.38367067559872403 0.08506187902573674 155.71112232367267 1.4282835410165116 36.66462738543647 0.3600502157482234 3.0000000028617963e-15 14.52287874486605 0.9921229106975304 KDS(ph)LTQAQEQGNLLN ddPTM_PC-9_Lapatinib_30min_R1 2 KDSLTQAQEQGNLLN 15 1 Q5JTD0-4;Q5JTD0-2;Q5JTD0 Q5JTD0-4 TJAP1 Tight junction-associated protein 1 1 KDS(0.861)LT(0.139)QAQEQGNLLN;KDS(0.792)LT(0.208)QAQEQGNLLN 108.34 0.0010947 172554000.0 171571.0 137068.0 170157.0 152803.0 151693.0 126861.0 123706.0 119606.0 138822.0 114149.0 True False 169124.36607773238 136750.62746743296 156167.3482850147 164040.64235586542 142770.71597991278 121435.45075743482 130110.8913818932 125163.33140317023 123186.4044995329 133879.5025560182 1.2632581003725116 1.0214455899267583 1.166476908738668 1.2252857175595429 1.066412059009364 0.9070503582624494 0.9718507232087441 0.9348954023099919 0.9201289379454404 1.0 17.030575570092125 -6.561860288794237 4.272825615823182 0.9453851652734918 1.1579818450084998 0.7292983862608959 0.06371360651344467 0.11116001872305396 4.510947200310693 0.0209517762437208 0.021477914243038007 2.7424562698254824e-07 6.561860288794237 0.21259667973500795 KDS(ph)QNSSQHSVSSHR ddPTM_PC-9_AZD4547_30min_R2 1 KDSQNSSQHSVSSHR 15 1 Q96QZ7-7;Q96QZ7-6;Q96QZ7-2;Q96QZ7;A0A087WT53;Q96QZ7-4;Q96QZ7-3;Q96QZ7-5;A0A087WXD2;H7C5T8;H7C4U7;H7C535 Q96QZ7-7 MAGI1 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 1 KDS(0.829)QNS(0.085)S(0.085)QHSVSSHR 65.092 0.012694 1013600.0 0.0 0.0 2312.6 9165.7 3864.5 3055.4 711.79 4286.3 2095.7 3642.6 True False 0.0 0.0 2281.9334129740023 7052.689473653369 3327.9808811256244 2864.345354993269 775.1379310800587 3623.950824375312 2206.474423543654 3515.0736827211513 0.0 0.0 0.6491850865576938 2.006412983125183 0.9467741451579782 0.8148749111784966 0.22051825965707642 1.0309743554422093 0.6277178297541516 1.0 11.779339215946314 -5.352666060881381 4.309685252493054 0.9390681606763912 2.582903525415892e-07 0.4341290660712527 0.4248196311227562 0.2109775738858903 6.8483378180190755 0.12054521049506461 0.2702916885116819 4.439498760995225e-06 5.352666060881381 -0.9390679023860387 KDS(ph)QNSSQHSVSSHR ddPTM_PC-9_Lapatinib_30min_R1 1 KDSQNSSQHSVSSHR 15 1 Q96QZ7-7;Q96QZ7-6;Q96QZ7-2;Q96QZ7;A0A087WT53;Q96QZ7-4;Q96QZ7-3;Q96QZ7-5;A0A087WXD2;H7C5T8;H7C4U7;H7C535 Q96QZ7-7 MAGI1 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 1 KDS(0.755)QNS(0.122)S(0.122)QHSVSSHR 46.408 0.045191 347840.0 590.04 0.0 931.31 0.0 531.32 962.28 0.0 0.0 2070.9 849.75 True False 581.6259213999164 0.0 854.7412867605615 0.0 500.0688022153114 921.1255275842409 0.0 0.0 1837.6534344562288 996.6281552792971 0.5835937087658539 0.0 0.8576330923753875 0.0 0.5017606612520104 0.9242419278493119 0.0 0.0 1.8438706800744968 1.0 9.960911521279664 -8.25949886861366 24.999992214968337 1.4219353702255069 0.3628441211062516 0.5450120396542812 0.3886765466460989 119.91707823496749 1544970.7438201953 0.2840805600942962 0.0950439001792728 5.501753537779912e-09 8.25949886861366 -1.0590912491192552 KDS(ph)SSEVFSDAAK ddPTM_PC-9_AZD4547_30min_R2 5 KDSSSEVFSDAAK 13 1 Q5T5U3;E7ESW5;A0A1B0GV73;Q5T5U3-3;A0A1B0GTZ9 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 KDS(0.877)S(0.109)S(0.014)EVFSDAAK;KDS(0.994)S(0.005)S(0.001)EVFSDAAK;KDS(0.811)S(0.158)S(0.031)EVFSDAAK;KDS(0.678)S(0.161)S(0.161)EVFSDAAK;KDS(0.442)S(0.442)S(0.117)EVFSDAAK 151.49 4.4338e-05 57989500.0 193043.0 203640.0 223274.0 230799.0 251985.0 253527.0 228524.0 256204.0 235508.0 253206.0 True False 254426.65845616005 269462.64760275534 220313.24087536018 177591.85635900398 217001.23232771142 237673.9166116974 248862.19329035128 216613.55878222585 247956.47208088863 244341.33500990798 1.0412755518661756 1.1028123734849393 0.9016617710893104 0.7268187200164176 0.8881069276261099 0.9727126873644191 1.0185022246860522 0.8865203211459994 1.0147954379918325 1.0 17.898538418146053 -9.997413920657218 18.559373198836617 0.9999999996370769 0.9457868550800422 0.019650302033695888 0.10063964321625753 0.0 0.0 0.10678295769443891 0.02589867138764905 1.0059724320205784e-10 9.997413920657218 -0.05421314455703463 KDS(ph)SSEVFSDAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KDSSSEVFSDAAK 13 1 Q5T5U3;E7ESW5;A0A1B0GV73;Q5T5U3-3;A0A1B0GTZ9 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 KDS(0.954)S(0.025)S(0.017)EVFS(0.004)DAAK;KDS(0.805)S(0.146)S(0.049)EVFSDAAK 98.552 0.0044181 0.0 37377.0 36441.6 34080.0 47176.0 54040.0 52777.0 67271.0 64500.0 55623.0 44516.0 True False 43704.18787059967 40059.28121385574 34892.59644911974 44532.8816666556 43451.24992938589 50009.281211401445 60898.60388013624 62806.94334339902 56436.381146622494 52586.39841153788 0.8310930048598009 0.7617802782452281 0.663528925788993 0.8468517147370322 0.8262830549705861 0.9509927038553188 1.158067593896573 1.194357195788078 1.0732125198032179 1.0 15.682402071048724 -6.917365396715006 2.0085049192639355 1.123336382409574 0.7718469707538288 0.8273886119584445 0.06883501138906603 0.12348075166965258 1.014303128135919 0.029753309391326477 0.02450459264284353 1.2095800166614826e-07 6.917365396715006 -0.3514894116557451 KDS(ph)SSEVFSDAAK ddPTM_PC-9_Lapatinib_30min_R1 4 KDSSSEVFSDAAK 13 1 Q5T5U3;E7ESW5;A0A1B0GV73;Q5T5U3-3;A0A1B0GTZ9 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 KDS(0.817)S(0.169)S(0.014)EVFSDAAK;KDS(0.476)S(0.476)S(0.048)EVFSDAAK;KDS(0.754)S(0.214)S(0.031)EVFSDAAK;KDS(0.659)S(0.219)S(0.122)EVFSDAAK 130.87 3.4498e-05 56257600.0 152165.0 197419.0 195951.0 180101.0 286695.0 335736.0 358966.0 362112.0 333982.0 326255.0 True False 149995.0991963567 196961.88843488717 179840.66517273424 193346.22833932366 269832.1637640566 321377.3539188417 377551.5030458728 378937.0454748478 296365.4301736252 382647.7420425379 0.39199264157602726 0.5147342236583522 0.4699901382215444 0.5052851672592122 0.705171190410579 0.8398778265444855 0.9866816436196334 0.990302578167892 0.7745124238592241 1.0 18.545657360956724 -6.532277292310772 1.5667144181839887 0.9374239566616388 0.4596589808835871 0.9084945873410386 0.0675344003030392 0.10488654864699465 0.5255294469602033 0.026819328700975656 0.02929915718001225 2.9357745932241696e-07 6.532277292310772 -0.4777649757780517 KDS(ph)SSVVEWTQAPK ddPTM_PC-9_AZD4547_30min_R2 1 KDSSSVVEWTQAPK 14 1 Q8TC07-2;Q8TC07-3;Q8TC07;F8WCB5 Q8TC07-2 TBC1D15 TBC1 domain family member 15 1 KDS(0.482)S(0.482)S(0.034)VVEWT(0.002)QAPK 203.06 1.8629e-10 20533000.0 94874.0 72183.0 88313.0 114700.0 136470.0 94291.0 87885.0 142330.0 120650.0 115630.0 True False 125041.95849820905 95514.74313450055 87141.91191731095 88257.68709733478 117523.4961436705 88394.96886419784 95706.59474419535 120336.168918027 127027.31268814325 111581.82889503271 1.1206301217363854 0.8560062519171755 0.7809686647033462 0.790968278359737 1.0532494162129862 0.7921986020443595 0.8577256323180406 1.0784566816092402 1.1384229309204137 1.0 16.76774257779124 -7.767000023375193 24.853622692664594 1.0813299416342375 0.8857166139288984 0.35103039707134287 0.11112840643848115 135.07360317822224 603704.1954768403 0.05887512516737915 0.029552943541057648 1.7100152230515023e-08 7.767000023375193 -0.195613327705339 KDS(ph)SSVVEWTQAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KDSSSVVEWTQAPK 14 1 Q8TC07-2;Q8TC07-3;Q8TC07;F8WCB5 Q8TC07-2 TBC1D15 TBC1 domain family member 15 1 KDS(0.881)S(0.112)S(0.007)VVEWTQAPK;KDS(0.926)S(0.069)S(0.005)VVEWTQAPK;KDS(0.81)S(0.095)S(0.095)VVEWTQAPK 145.33 0.00027064 17784400.0 169516.0 176405.0 121118.0 147479.0 168822.0 128626.0 87711.0 159908.0 102330.0 86361.0 True False 198211.71070638613 193917.32257997006 124005.91246257261 139216.2297633688 135742.54099886728 121880.62612686807 79402.3791073514 155710.58443653118 103826.38266065973 102017.56566670025 1.9429174712319646 1.9008228760673809 1.2155349096224282 1.364629991448724 1.3305800830648056 1.19470235670063 0.7783206606474564 1.5263115074246176 1.0177304465376975 1.0 16.638458055245287 -4.996868190283042 0.8918376142119212 1.1419292718734562 2.34145846266478 0.6645351617652356 0.20748813588877354 1.0114777208688124 0.7872286390797315 0.07432146573035597 1.109545341724419 1.007237322105102e-05 4.996868190283042 1.199529190791324 KDSETGENIR ddPTM_PC-9_AZD4547_30min_R2 2 KDSETGENIR 10 1 P38646 P38646 HSPA9 Stress-70 protein, mitochondrial 0 ; 73.84100000000001 0.017024 18168500.0 33660.0 34302.0 45904.0 62873.0 52017.0 49342.0 42273.0 51452.0 46098.0 37713.0 False True 44363.179828506356 45389.45068783006 45295.2829668592 48378.60122816681 44795.33742877777 46256.63693986971 46035.21510634786 43501.27564933824 48534.64616906777 36392.67934894383 1.2190138407545925 1.2472137666101062 1.2446262209098309 1.329349805885365 1.2308886905321468 1.2710423570726224 1.2649581160251635 1.1953303913744597 1.3336376171620439 1.0 15.151360650600855 -10.815129961476007 4.356213037637544 0.9997864576011001 1.2585762284543058 0.776056483008865 0.04182675056359766 8.216032213010914e-05 1.3348549938771296e-05 0.038357731887512195 0.009295483442931636 1.5306293563521234e-11 10.815129961476007 0.25878977085320576 KDSETGENIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KDSETGENIR 10 1 P38646 P38646 HSPA9 Stress-70 protein, mitochondrial 0 ; 64.82 0.031905 9065200.0 32952.0 30210.0 41502.0 38916.0 50008.0 39108.0 38270.0 37142.0 37932.0 33941.0 False True 38530.12276833347 33209.049149065424 42491.56507721147 36735.66268737428 40209.291385431694 37057.10763430068 34644.78854919377 36167.061855201966 38486.68373970628 40094.234623191835 0.9609891080461322 0.8282749243417707 1.0597923984969384 0.916233045289887 1.0028696585262487 0.9242502814323738 0.8640840478634321 0.9020514344544125 0.9599056847301508 1.0 15.29110717786245 -6.970587210952811 24.9847571526688 0.9191791777360738 0.9517948890540313 0.01866361340969247 0.06511370117661479 691.5662742938724 587450.6015251413 0.02243033543282236 0.019781439210772765 1.0700714795961272e-07 6.970587210952811 0.032615711317957485 KDSETGENIR ddPTM_PC-9_Lapatinib_30min_R1 1 KDSETGENIR 10 1 P38646 P38646 HSPA9 Stress-70 protein, mitochondrial 0 60.167 0.043907 8821500.0 20295.0 19939.0 21394.0 14401.0 16651.0 16157.0 12552.0 11630.0 19498.0 14797.0 False True 20005.58957835282 19892.832470548517 19635.067903228202 15460.097580327709 15671.620917125556 15466.00277380656 13201.881142592316 12170.372257402378 17301.929916957622 17354.64173423685 1.1527515165516922 1.1462542860394738 1.1314015122820182 0.8908335773839902 0.903021863379002 0.8911738433237474 0.7607118225061332 0.7012747623244182 0.9969626675049569 1.0 14.083033962314692 -5.778394122759934 3.7435745897703825 0.8584059677717164 1.1497066068066384 0.6570607174820233 0.08755704201688398 0.12766769649701593 3.8393005280792925 0.025463166645511126 0.04238668587309185 1.6657348700486939e-06 5.778394122759934 0.291300639034922 KDSNELSDS(ph)AGEEDSADLKR ddPTM_PC-9_Lapatinib_30min_R1 1 KDSNELSDSAGEEDSADLKR 20 2 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 KDS(0.057)NELS(0.004)DS(0.939)AGEEDSADLKR 69.084 0.037469 0.0 5649.3 5429.4 6294.9 6624.5 6596.0 5110.3 5368.0 5015.6 7110.9 5683.9 True False 5568.7399460452625 5416.828557881344 5777.357621016694 7111.687828684186 6208.036248234951 4891.744381691139 5645.9287741742755 5248.643086348008 6309.99556090337 6666.354541679319 0.8353501019527899 0.8125623268330989 0.8666442183498573 1.0668031206892101 0.9312490371493334 0.7337960126643462 0.8469289682801677 0.7873333249128128 0.9465436501242284 1.0 12.702682332071346 KDSQNSS(ph)QHSVSSHR ddPTM_PC-9_AZD4547_30min_R2 1 KDSQNSSQHSVSSHR 15 1 Q96QZ7-7;Q96QZ7-6;Q96QZ7-2;Q96QZ7;A0A087WT53;Q96QZ7-4;Q96QZ7-3;Q96QZ7-5;A0A087WXD2;H7C5T8;H7C4U7;H7C535 Q96QZ7-7 MAGI1 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 1 KDS(0.29)QNS(0.283)S(0.427)QHSVSSHR 58.32 0.0217 1243300.0 0.0 0.0 635.45 5447.9 2477.5 2626.0 0.0 2449.0 921.13 2795.8 True False 0.0 0.0 627.0235178043458 4191.970824215955 2133.5418897629042 2461.7958048741 0.0 2070.5633224214694 969.819051275834 2697.9198929752893 0.0 0.0 0.23240998349764155 1.5537788335119964 0.7908099478113176 0.9124792071417698 0.0 0.7674665685266268 0.35946917986742344 1.0 11.397631796875979 -5.538991910280248 24.996145153749172 0.7464983735672898 0.0290509546699847 0.4158131910493935 0.38139965495488437 229.26795927688877 355659.0896751858 0.10707253832763766 0.18552025570433864 2.8907337283361582e-06 5.538991910280248 -0.717447418897305 KDSS(ph)SVVEWTQAPK ddPTM_PC-9_AZD4547_30min_R2 1 KDSSSVVEWTQAPK 14 1 Q8TC07-2;Q8TC07-3;Q8TC07;F8WCB5 Q8TC07-2 TBC1D15 TBC1 domain family member 15 1 KDS(0.28)S(0.541)S(0.174)VVEWT(0.004)QAPK 104.16 0.0016057000000000003 21259000.0 49407.0 43208.0 45678.0 63229.0 69449.0 48741.0 47594.0 79559.0 60182.0 63056.0 True False 65117.39827055893 57174.14102150781 45072.27987452502 48652.53092831193 59807.20512700058 45693.21756487757 51829.773798205 67264.98463394443 63363.09765601195 60848.42863275265 1.0701574343615579 0.9396157354626066 0.7407303834673578 0.7995692250649825 0.9828882433096783 0.7509350461727857 0.8517849180793272 1.1054514659683088 1.041326770136275 1.0 15.892932386399599 -7.755333582718067 24.985002119161067 1.0550418498819023 0.8700300431067212 0.38372189853852934 0.09979409268091839 143.65366572970424 587839.8507824147 0.050286437954980424 0.028076574711912754 1.7565738667094726e-08 7.755333582718067 -0.18501180677518114 KDSS(ph)SVVEWTQAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KDSSSVVEWTQAPK 14 1 Q8TC07-2;Q8TC07-3;Q8TC07;F8WCB5 Q8TC07-2 TBC1D15 TBC1 domain family member 15 1 KDS(0.353)S(0.613)S(0.034)VVEWTQAPK 101.28 0.00080188 12161000.0 54376.0 47661.0 36606.0 47758.0 53749.0 44210.0 30689.0 51773.0 31717.0 25403.0 True False 63580.78282504561 52392.469099424234 37478.82586902807 45082.27409352507 43217.269290424905 41891.54977274301 27781.915750880773 50414.01360802785 32180.801122331137 30008.36280996265 2.118768798807546 1.745928940916102 1.248946039021671 1.5023236815357999 1.4401741795815983 1.3959958441596552 0.9258057804358888 1.6799988032432949 1.0723944297170136 1.0 14.873076990375736 -1.5228787452852146 0.5921417430908223 1.2572787497116182 53.639940229813824 0.6025665886272125 0.22200377728871368 112.6903307381134 0.8974118721310715 0.09785859646391079 7619.181265521337 0.029999999999663105 1.5228787452852146 52.38266148010221 KDSS(ph)SVVEWTQAPK ddPTM_PC-9_Lapatinib_30min_R1 2 KDSSSVVEWTQAPK 14 1 Q8TC07-2;Q8TC07-3;Q8TC07;F8WCB5 Q8TC07-2 TBC1D15 TBC1 domain family member 15 1 KDS(0.297)S(0.517)S(0.138)VVEWT(0.048)QAPK;KDS(0.062)S(0.898)S(0.04)VVEWTQAPK 140.49 3.6343e-05 26685000.0 194493.0 161350.0 182651.0 171656.0 117289.0 91660.0 101620.0 93429.0 134193.0 151798.0 True False 191719.49415435246 160976.40398831415 167634.13983324904 184280.15486762996 110390.29161904613 87739.91546989606 106881.38636952123 97770.05241933335 119078.77122506377 178036.08204187918 1.0768575221131553 0.904178535845604 0.9415739658538245 1.0350719514501672 0.6200444895944136 0.4928209746227572 0.6003355339193528 0.5491586385075304 0.6688462802560047 1.0 17.441810131963166 -6.266765174831077 24.50421729157684 0.621796624975377 0.9799141804213121 0.5822631027910888 0.13684749543499689 213.0063192435555 980050.0140680115 0.03969159323713193 0.04635031969009551 5.410467905379761e-07 6.266765174831077 0.35811755544593504 KDWDDDQND ddPTM_PC-9_AZD4547_30min_R2 1 KDWDDDQND 9 1 P50990-2;P50990;P50990-3;H7C2U0 P50990-2 CCT8 T-complex protein 1 subunit theta 0 82.287 0.036126 22250000.0 176230.0 180260.0 226400.0 316470.0 267750.0 255140.0 197920.0 247700.0 186440.0 252970.0 False True 232267.47418828524 238525.51982357446 223397.788072868 243512.7309127598 230577.53420141982 239186.05546670858 215534.49657815514 209423.65657974553 196294.8377751965 244113.59729807492 0.9514729075278631 0.9771087004724397 0.9151386507982515 0.9975385787929649 0.9445501469542195 0.9798145540194979 0.8829270428348026 0.8578942709366114 0.8041126751965015 1.0 17.897193130916627 -7.318584408813039 6.100247725986613 0.8734677518674467 0.9604670827040753 0.333300981798787 0.05053662835627459 0.22382687427853248 18.117987126946044 0.020123011612952667 0.013542444123594132 4.801927416406217e-08 7.318584408813039 0.08699933083662859 KDWDDDQND ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KDWDDDQND 9 1 P50990-2;P50990;P50990-3;H7C2U0 P50990-2 CCT8 T-complex protein 1 subunit theta 0 85.67 0.027681 14099000.0 129670.0 144470.0 139470.0 172410.0 172950.0 162720.0 161350.0 165080.0 155180.0 123410.0 False True 151620.5699007587 158812.02683103233 142795.49374292052 162750.42666076144 139061.68903196297 154186.67674781126 146065.7599271601 160746.82491671774 157449.21392828284 145783.25608697743 1.0400410442904267 1.089370831011496 0.9795054492247426 1.1163862780212634 0.9538934220881702 1.0576432498929793 1.0019378346167143 1.1026425752269706 1.0800226181966004 1.0 17.153465503103945 -7.760439410157595 24.999994671057586 1.0684994392903262 1.0351205245857542 0.04700251002140543 0.05182797338597055 70.40011060469135 1760251.3236984634 0.024358096321094057 0.013004124128734695 1.7360434470716356e-08 7.760439410157595 -0.033378914704571994 KDWDDDQND ddPTM_PC-9_Lapatinib_30min_R1 1 KDWDDDQND 9 1 P50990-2;P50990;P50990-3;H7C2U0 P50990-2 CCT8 T-complex protein 1 subunit theta 0 86.67 0.025937 32900000.0 236110.0 244040.0 265090.0 222500.0 241660.0 232670.0 209960.0 198240.0 236470.0 175150.0 False True 232743.0281027284 243474.94037377276 243295.32347699237 238863.39223824177 227446.0339218401 222719.24648026095 220830.70145782974 207450.95411070017 209836.25846050732 205424.44412729537 1.1329860430753047 1.1852286684193174 1.1843542987816462 1.1627797911441604 1.1072004351190972 1.0841905763768236 1.0749971961515328 1.0098649894953544 1.021476579147894 1.0 17.648248337314783 -7.0219053608217505 0.7971160029999307 1.0034249058527678 1.1744575320460027 0.9185511172379379 0.0190358741526228 0.16822205914828192 0.22188371104542964 0.014707111143798796 0.01092940637692024 9.508119670449943e-08 7.0219053608217505 0.1710326261932349 KDYDT(ph)LSK ddPTM_PC-9_AZD4547_30min_R2 1 KDYDTLSK 8 1 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 KDY(0.117)DT(0.883)LSK 147.19 0.0038217 7005600.0 15681.0 24041.0 16929.0 25898.0 24761.0 28123.0 16975.0 21475.0 26637.0 24066.0 True False 20667.231814937866 31811.783102621495 16704.510398787905 19927.61622011138 21323.362555971427 26364.464364232426 18485.74211506764 18156.532196407115 28044.977439486713 23223.456665120302 0.8899291829359032 1.369812580501857 0.7192947475332855 0.8580814005195445 0.9181821148958131 1.1352515150696605 0.7959944284621369 0.7818186783398492 1.2076142601806532 1.0 14.50329510379743 -5.268122455688567 24.994913630128732 0.9192157072991605 1.1298708816581529 0.16558137001886353 0.1814617536555208 783.7659793011085 2931318.372602277 0.04568934509814258 0.09879405442403143 5.393585210396573e-06 5.268122455688567 0.2106551743589924 KEAESSPFVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KEAESSPFVER 11 1 P14625 P14625 HSP90B1 Endoplasmin 0 92.11200000000001 0.020943 0.0 6747.4 11181.0 11035.0 12728.0 12279.0 6099.0 9887.8 9354.8 6985.8 7408.0 False True 7889.60155277535 12290.975787345262 11298.116250470543 12014.891424732754 9873.018095539037 5779.15770332412 8951.156002527257 9109.24641222991 7087.954109164825 8751.011758304263 0.9015645014176242 1.404520543088261 1.2910640006567478 1.372971692482442 1.128214470306253 0.6603988044970909 1.0228709833503615 1.0409363698529717 0.8099582431070006 1.0 13.095234110099033 -6.531815803452457 24.804147404644176 0.9141618151767643 1.2566958252512783 0.4818512680044561 0.1652825968173854 150.8345580990425 418626.81642918434 0.05321679274148577 0.053292386123326194 2.938895856349321e-07 6.531815803452457 0.342534010074514 KEAESSPFVER ddPTM_PC-9_Lapatinib_30min_R1 1 KEAESSPFVER 11 1 P14625 P14625 HSP90B1 Endoplasmin 0 67.214 0.025477 3274200.0 33674.0 22786.0 23771.0 19742.0 18136.0 21892.0 16618.0 14534.0 20199.0 15614.0 False True 33193.80258494472 22733.240416967667 21816.64013871355 21193.89253738141 17069.276136747885 20955.730192744526 17478.398727501524 15209.302698975574 17923.975915100375 18312.859095652784 1.812595314121347 1.241381277397816 1.1913290013732762 1.1573229732550359 0.9320923645833048 1.144317776011236 0.9544330918622451 0.8305258408604285 0.9787644748140543 1.0 14.160569429074128 -1.5228787452805728 0.6131586001802664 0.9651060332081397 56.70648018708677 0.8802935312680603 0.09036637333172236 58.433748131184444 0.43206939523599464 0.04069225655846623 4380.413273900467 0.02999999999998375 1.5228787452805728 55.74137415387863 KEDEVEEWQHR ddPTM_PC-9_AZD4547_30min_R2 2 KEDEVEEWQHR 11 1 P15311;E7EQR4 P15311 EZR Ezrin 0 ; 123.51 0.00022347 13801100.0 113825.0 116111.0 155995.0 183766.0 176554.0 163604.0 148345.0 181650.0 154051.0 162063.0 False True 150018.9822929213 153641.61007564072 153926.40437467754 141401.58785639764 152042.52464387438 153373.81601699267 161547.41761765568 153580.1664017391 162193.82135865037 156389.2236981377 0.9592667496226451 0.9824309274160704 0.9842519883069828 0.9041645230577449 0.9722058914835889 0.9807185712043346 1.0329830521409475 0.9820380379800295 1.0371163531811929 1.0 17.254781578815525 -6.972357001999593 2.9979609116432546 1.0114927023073348 0.9598717285097157 0.4818811251468945 0.02556679171647699 0.239401314085001 4.406790552225398 0.010161259566638771 0.008374112920392454 1.0657197101722903e-07 6.972357001999593 -0.051620973797619096 KEDEVEEWQHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KEDEVEEWQHR 11 1 P15311;E7EQR4 P15311 EZR Ezrin 0 ;; 132.32 4.5286999999999995e-05 12647800.0 122363.0 151781.0 138886.0 147251.0 168719.0 127362.0 138681.0 130111.0 107439.0 98464.0 False True 143076.63912058744 166848.81459431638 142197.56896808793 139001.0038641832 135659.72310947572 120682.91251201292 125544.13171650728 126695.72411400017 109010.09212038151 116314.74375940487 1.230081711881162 1.4344597185326773 1.222524027239584 1.195041998731515 1.1663157973342195 1.0375547296191747 1.0793483926353589 1.0892490497685159 0.9371992629401058 1.0 16.827674455172343 -6.21946699990822 0.6672352773679456 1.0060106104261588 1.3553017192399446 0.7684990851853638 0.06505688926023039 0.39865341811009797 0.373126213246224 0.04049081063787751 0.08000169734834549 6.032995482145168e-07 6.21946699990822 0.3492911088137858 KEDEVEEWQHR ddPTM_PC-9_Lapatinib_30min_R1 2 KEDEVEEWQHR 11 1 P15311;E7EQR4 P15311 EZR Ezrin 0 ; 136.5 3.2573e-05 16184800.0 168728.0 209725.0 244023.0 239750.0 261480.0 239036.0 233790.0 206090.0 252698.0 202267.0 False True 166321.90777907462 209239.39464796515 223960.3708960204 257382.01478255395 246100.26048945967 228812.98750013148 245894.50225674457 215665.69376853414 224236.49021209148 237228.58144616385 0.7011040017402766 0.8820159585005548 0.9440699325972469 1.0849536477161952 1.0373971761295093 0.9645253792998708 1.0365298344649392 0.9091050178432099 0.9452338704094103 1.0 17.855918311582847 -4.809785043431461 1.7174748019509718 0.9943194860102093 0.6122736734460442 0.7694786942226852 0.049045333911448684 0.43817697559869806 1.358982111362447 0.014731800315620826 0.2739351544758204 1.5495834044130245e-05 4.809785043431461 -0.38204581256416503 KEDGTFYEFGEDIPEAPER ddPTM_PC-9_Lapatinib_30min_R1 1 KEDGTFYEFGEDIPEAPER 19 1 O43776 O43776 NARS Asparagine--tRNA ligase, cytoplasmic 0 146.78 0.0001025 5058400.0 21559.0 25314.0 24275.0 22865.0 20856.0 19805.0 21911.0 19317.0 21402.0 19840.0 False True 21251.564706563593 25255.386988287522 22279.203204209807 24546.568375404004 19629.291084473633 18957.986317709918 23045.444368653607 20214.538340175553 18991.481386948773 23269.317564861754 0.9132869774683421 1.0853514254506917 0.9574497894967454 1.0548899127351712 0.8435696934281902 0.814720339987012 0.9903790390249256 0.8687207213459872 0.8161597921387775 1.0 14.506141280012232 -6.264107585603235 24.99897585923287 0.8837234416410115 1.0054096817444054 0.3568819943390885 0.07462242306502732 247.92399669023277 2322847.6424896913 0.02199381382005392 0.02609374896777175 5.443677826254057e-07 6.264107585603235 0.1216862401033939 KEDLEAEEEYSSLCELLGSPEQRPGMQDPLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 KEDLEAEEEYSSLCELLGSPEQRPGMQDPLSPK 33 2 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4;A8MXE8;Q7Z5J4-4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 KEDLEAEEEYS(0.002)S(0.014)LCELLGS(0.007)PEQRPGMQDPLS(0.977)PK 50.218999999999994 0.018374 3045500.0 9660.8 10589.0 11780.0 15252.0 14723.0 12928.0 12638.0 11019.0 12415.0 10099.0 True False 12732.73344287684 14011.687170818965 11623.78950308474 11735.887041051003 12678.965587479004 12119.610116303274 13762.75751694992 9316.266741430036 13071.231554275171 9745.437083896368 1.3065328248762453 1.4377689835966687 1.1927417316450808 1.2042442981283734 1.301015591022601 1.2436189379673956 1.4122257830479337 0.9559619195350915 1.3412668351093702 1.0 13.25051117662332 -14.522878743559705 0.10219423204002007 0.13947173081251513 1.437915000245125 0.31496026493071594 0.12524369905793495 213.5199730987184 1.4718724438818804 38.72617794300322 1.9084090800040214 3.0000000118857095e-15 14.522878743559705 1.29844326943261 KEEAS(ph)SPGAGEGPAEEGTR ddPTM_PC-9_Lapatinib_30min_R1 1 KEEASSPGAGEGPAEEGTR 19 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 KEEAS(0.5)S(0.5)PGAGEGPAEEGTR 122.87 1.3717000000000001e-05 8364100.0 20971.0 18984.0 25426.0 23138.0 25902.0 26615.0 26050.0 19434.0 28470.0 24945.0 True False 20671.949694389594 18940.043714373478 23335.5724271983 24839.645706105315 24378.495285291334 25476.738492595283 27398.74153637107 20336.974587305034 25263.40879760917 29256.710012876803 0.7065712339251822 0.647374352961675 0.7976143734865464 0.8490238887138233 0.8332616782461728 0.8707998432285163 0.9364942785539461 0.6951217200551288 0.863508193043235 1.0 14.83647992363378 -5.435270206766212 3.2513791753940016 0.8527211925693416 0.677009821204973 0.48685532365990203 0.07520700714911838 0.21359992753029294 4.272417563390709 0.020033605255030847 0.04598280593245958 3.6705385804649898e-06 5.435270206766212 -0.17571137136436865 KEEASS(ph)PGAGEGPAEEGTR ddPTM_PC-9_AZD4547_30min_R2 2 KEEASSPGAGEGPAEEGTR 19 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 KEEAS(0.051)S(0.949)PGAGEGPAEEGTR;KEEAS(0.037)S(0.963)PGAGEGPAEEGTR 108.57 8.2946e-05 26425000.0 53450.0 50847.0 63046.0 93455.0 91315.0 76902.0 61908.0 83218.0 64839.0 65883.0 True False 70445.98817093477 67282.29838272092 62209.96884647539 71910.39361535686 78637.48846163433 72093.30578310274 67417.69206831277 70358.5702593998 68266.25716855803 63576.45622322455 1.1080515076774722 1.058289536404557 0.9785063928075629 1.1310852772741982 1.2368963785198832 1.1339623197929516 1.060419156292719 1.1066765032068229 1.0737663157705273 1.0 15.956204981875194 -4.3676797408797 18.520364857035396 1.0927262445600798 12.584609829346263 0.0016089824888486648 0.0695592633839005 1869.9945265896256 223757.53485683646 0.017987245535712095 2478.0869278135738 4.288646588582316e-05 4.3676797408797 11.491883584786184 KEEASS(ph)PGAGEGPAEEGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KEEASSPGAGEGPAEEGTR 19 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 KEEAS(0.064)S(0.936)PGAGEGPAEEGTR 108.79 8.1072e-05 9453400.0 19147.0 16379.0 18449.0 16944.0 24102.0 25203.0 21352.0 22516.0 22281.0 18265.0 True False 22388.20892951205 18004.998874960023 18888.89412822213 15994.682613189183 19379.38611765468 23881.310312654197 19329.383984906864 21924.978857673996 22606.817473489304 21576.29991433956 1.0376296685898816 0.834480376452032 0.8754464019879801 0.7413079479192423 0.8981793076010769 1.1068306617661878 0.8958618512741658 1.01616027514999 1.0477615514819973 1.0 14.397159860088179 -6.567389336821696 11.195564576043328 1.0066047960918525 0.8635113163037489 0.39626964373518825 0.08388957087654066 0.6344682136226348 157.1478295003597 0.027380669065693492 0.027389966642892092 2.7077630848839766e-07 6.567389336821696 -0.1430934797881036 KEEASS(ph)PGAGEGPAEEGTR ddPTM_PC-9_Lapatinib_30min_R1 1 KEEASSPGAGEGPAEEGTR 19 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 KEEAS(0.268)S(0.732)PGAGEGPAEEGTR 93.416 0.00037588 10079000.0 27927.0 26296.0 27605.0 24135.0 22631.0 30718.0 24297.0 22515.0 22875.0 28096.0 True False 27528.755858815428 26235.113227621434 25335.423458381545 25909.968411999824 21299.889074257895 29404.26274715542 25554.97977386596 23561.129095048527 20298.57661557112 32952.35616443324 0.835410849574644 0.7961528789233595 0.7688501341742311 0.7862857600442381 0.6463844032266104 0.8923265638556246 0.7755129753498006 0.7150059005637652 0.6159977306108437 1.0 15.008094004273351 -4.844218359642266 1.6166081612169907 0.7641100458591286 0.8559436154199448 0.022086128897195523 0.10530906830797118 3.432087636314346 9.628818975692857 0.028578247186271402 0.4825465930131386 1.431467988144077e-05 4.844218359642266 0.09183356956081623 KEEELQAALAR ddPTM_PC-9_AZD4547_30min_R2 2 KEEELQAALAR 11 1 P35579;Q7Z406;Q7Z406-6;Q7Z406-2;Q7Z406-4;Q7Z406-5;A0A0C4DFM8;P35749-4;P35749-3;P35749;P35749-2 P35579;Q7Z406;P35749-4 MYH9;MYH14;MYH11 Myosin-9;Myosin-14;Myosin-11 0 ; 96.756 0.0035898 23028000.0 86075.0 79833.0 107110.0 149097.0 156328.0 113603.0 100452.0 140995.0 99235.0 117519.0 False True 113445.05952877876 105637.45603059683 105689.65141556913 114724.99017568715 134624.55561770123 106499.38645129952 109392.03339869053 119207.46249277893 104480.35950773227 113404.69557999985 1.0003559283729166 0.9315086601160733 0.9319689178215002 1.0116423274092379 1.1871162382578075 0.9391091427618262 0.9646164370814907 1.051168665310561 0.9213054095632924 1.0 16.791120851487072 -5.778219688048452 20.748224831208354 1.0152870366554023 0.9523009979794501 0.11139486582447977 0.07170625017869992 66.02765545113934 81640.81572417312 0.020720453695293517 0.030908413269316717 1.6664040481147464e-06 5.778219688048452 -0.0629860386759522 KEEELQAALAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KEEELQAALAR 11 1 P35579;Q7Z406;Q7Z406-6;Q7Z406-2;Q7Z406-4;Q7Z406-5;A0A0C4DFM8;P35749-4;P35749-3;P35749;P35749-2 P35579;Q7Z406;P35749-4 MYH9;MYH14;MYH11 Myosin-9;Myosin-14;Myosin-11 0 73.632 0.015349000000000002 9060700.0 51338.0 57369.0 72432.0 69105.0 89361.0 52137.0 61572.0 56532.0 55655.0 44090.0 False True 60028.50942828069 63064.21518148736 74159.05357988973 65233.27089143293 71851.35353330604 49402.843938057034 55739.45441732321 55048.094900605145 56468.84908608444 52083.167983752035 1.1525510400405616 1.2108367755425513 1.4238583490740144 1.2524827773875664 1.3795503675145284 0.9485376149444066 1.0702009223922746 1.0569267775297013 1.0842053444924964 1.0 15.668529583341908 -6.762046614741453 24.99990844559412 1.0379212205174502 1.2858342198460495 0.7080858305862099 0.08081316413397299 9.541759796445563 392822.7167904982 0.028292818244767984 0.026460760651826443 1.7296307003628507e-07 6.762046614741453 0.24791299932859934 KEEELQAALAR ddPTM_PC-9_Lapatinib_30min_R1 2 KEEELQAALAR 11 1 P35579;Q7Z406;Q7Z406-6;Q7Z406-2;Q7Z406-4;Q7Z406-5;A0A0C4DFM8;P35749-4;P35749-3;P35749;P35749-2 P35579;Q7Z406;P35749-4 MYH9;MYH14;MYH11 Myosin-9;Myosin-14;Myosin-11 0 ; 125.23 0.00029853 30804000.0 181133.0 213730.0 257060.0 205250.0 227840.0 208210.0 211820.0 185874.0 236870.0 173754.0 False True 178550.0102042757 213235.1213165324 235925.5190802953 220344.7696939284 214438.8991506745 199305.34366121606 222787.00315678 194510.38460639768 210191.2062483207 203787.1473873484 0.8761593284629319 1.046361971548803 1.1577055869566684 1.0812495906579824 1.0522690066566356 0.9780074269472276 1.0932338276138565 0.9544781753909244 1.031425234334331 1.0 17.636703539751892 -7.766995165114014 24.999871114224067 0.9947137948961629 1.0450212994160222 0.07421257673387183 0.07238012526254342 377.9978470833161 1700866.8491846707 0.03943559179537857 0.019765407993749623 1.710034352345996e-08 7.766995165114014 0.050307504519859325 KEEPEPETEAVSS(ph)SQEIPTMPQPIEK ddPTM_PC-9_AZD4547_30min_R2 1 KEEPEPETEAVSSSQEIPTMPQPIEK 26 1 A0A0A0MRY2;B0QZE2;B7Z2J6;E7ENI9;J3QKD2;Q15326-4;Q15326-5;Q15326-2;Q15326-6;Q15326-3;Q15326 A0A0A0MRY2 ZMYND11 Zinc finger MYND domain-containing protein 11 1 KEEPEPETEAVS(0.004)S(0.415)S(0.415)QEIPT(0.167)MPQPIEK 106.99 2.857e-10 14657000.0 131310.0 102720.0 149300.0 185650.0 172080.0 150950.0 147710.0 163680.0 148990.0 149650.0 True False 173063.84858232844 135922.23120091844 147320.18444911286 142851.26076390746 148189.6623170129 141511.07263737425 160855.90384781387 138387.01699221964 156865.30723088677 144410.79904991502 1.1984134823775168 0.9412193000465114 1.020146591656156 0.9892006809998433 1.0261674562564518 0.9799202938310833 1.1138772509126182 0.9582871772933458 1.0862436068695036 1.0 17.139819105534592 -4.7470848312141705 24.99483223317658 1.0135245826377004 1.1984139580721733 0.5463575568500323 0.05073998434681549 555.8433498338147 967806.4710875673 0.01169969762437116 0.24909146164759205 1.790256127200926e-05 4.7470848312141705 0.18488937543447292 KEEPEPETEAVSS(ph)SQEIPTMPQPIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KEEPEPETEAVSSSQEIPTMPQPIEK 26 1 A0A0A0MRY2;B0QZE2;B7Z2J6;E7ENI9;J3QKD2;Q15326-4;Q15326-5;Q15326-2;Q15326-6;Q15326-3;Q15326 A0A0A0MRY2 ZMYND11 Zinc finger MYND domain-containing protein 11 1 KEEPEPETEAVS(0.011)S(0.446)S(0.446)QEIPT(0.096)MPQPIEK 78.202 0.00022272 0.0 6777.1 6766.0 10094.0 11072.0 11920.0 9014.7 10736.0 10762.0 8901.6 7937.3 True False 7924.329176173609 7437.683765063776 10334.67924170817 10451.671735908327 9584.361568435968 8541.95326252763 9719.008358091043 10479.508903281552 9031.769059827308 9376.26965836777 0.8451473202993486 0.7932455055221327 1.1022165123509515 1.1146940219003645 1.022193464741331 0.9110183019218563 1.0365538441417796 1.1176629176752833 0.9632582454331381 1.0 13.194798346443964 -5.254862317102936 24.897701421139832 1.0358898036330644 0.8191963879486511 0.641677258656445 0.06402142882993726 307.2889860303425 1163245.208928435 0.017313608744707103 0.04354088909844786 5.560805216381868e-06 5.254862317102936 -0.21669341568441325 KEEPEPETEAVSS(ph)SQEIPTMPQPIEK ddPTM_PC-9_Lapatinib_30min_R1 3 KEEPEPETEAVSSSQEIPTMPQPIEK 26 1 A0A0A0MRY2;B0QZE2;B7Z2J6;E7ENI9;J3QKD2;Q15326-4;Q15326-5;Q15326-2;Q15326-6;Q15326-3;Q15326 A0A0A0MRY2 ZMYND11 Zinc finger MYND domain-containing protein 11 1 KEEPEPETEAVS(0.002)S(0.479)S(0.479)QEIPT(0.04)MPQPIEK;KEEPEPETEAVS(0.002)S(0.478)S(0.478)QEIPT(0.042)MPQPIEK;KEEPEPETEAVS(0.021)S(0.487)S(0.487)QEIPT(0.006)MPQPIEK 104.33 1.7282e-07 25280000.0 156433.0 136827.0 153485.0 136033.0 154239.0 136976.0 125125.0 118370.0 148885.0 116876.9 True False 154202.23673370085 136510.18548812566 140866.05576923318 146037.32061278517 145166.96526554137 131117.85578665134 131603.36025867306 123869.90233093002 132116.0034714449 137078.9164363201 1.1249157838604258 0.9958510691287915 1.0276274384957833 1.0653521665428882 1.0590028652070542 0.9565136579377765 0.9600554460160857 0.9036393455041183 0.9637952130502818 1.0 17.064647167422542 -6.774969517034878 9.601164821019161 0.9508810962138057 1.0504174287374926 0.6234533869602097 0.037775829292474514 0.1388607254627635 86.58086632050755 0.012888992574121986 0.011712400026734395 1.678921856875942e-07 6.774969517034878 0.09953633252368688 KEEPEPETEAVSSS(ph)QEIPTMPQPIEK ddPTM_PC-9_AZD4547_30min_R2 1 KEEPEPETEAVSSSQEIPTMPQPIEK 26 1 A0A0A0MRY2;B0QZE2;B7Z2J6;E7ENI9;J3QKD2;Q15326-4;Q15326-5;Q15326-2;Q15326-6;Q15326-3;Q15326 A0A0A0MRY2 ZMYND11 Zinc finger MYND domain-containing protein 11 1 KEEPEPET(0.001)EAVS(0.023)S(0.395)S(0.53)QEIPT(0.051)MPQPIEK 76.79899999999999 2.4276e-05 17655000.0 50181.0 41541.0 48007.0 67986.0 59298.0 63175.0 51811.0 67586.0 55063.0 63424.0 True False 66137.51417035876 54968.31587146951 47370.395812783405 52312.87807322931 51065.496257986124 59224.65726310788 56422.07862879353 57142.13667177514 57973.51776665758 61203.54506476313 1.0806157404832466 0.8981230713564753 0.7739812418162699 0.8547360780796918 0.8343552028554991 0.9676671049109775 0.921875988867801 0.933640961668309 0.9472248332235058 1.0 15.901327599448253 -6.775977400068713 24.9781805936974 0.947921482231122 0.880681904860147 0.14994115866559066 0.0764636981193593 488.2759152538699 838915.4430063869 0.02823104138907078 0.025006775096516075 1.6750300394153803e-07 6.775977400068713 -0.06723957737097508 KEEPS(ph)QNDISPK ddPTM_PC-9_Lapatinib_30min_R1 1 KEEPSQNDISPK 12 1 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 KEEPS(0.812)QNDIS(0.188)PK 109.95 0.0018371 3563900.0 20459.0 18474.0 12174.0 16436.0 14817.0 16871.0 15936.0 14524.0 14227.0 13806.0 True False 20167.250908278897 18431.22458803918 11173.100712998981 17644.758268888698 13945.493191342819 16149.466658221856 16761.088104553153 15198.83806246879 12624.605443048316 16192.348704661348 1.2454802744257403 1.1382675190741982 0.6900234744686878 1.0896972755909857 0.8612396784246797 0.9973517093028544 1.0351239594863764 0.9386432036319381 0.7796648697056546 1.0 13.983024643683239 -5.018283392376049 22.50751016684468 0.9308525908412508 1.21867751013463 0.4755216554740702 0.11479942458861465 142.72621194087895 175706.9339886134 0.02776055281497103 0.0771799192326258 9.587747931796817e-06 5.018283392376049 0.2878249192933793 KEEPSQNDIS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 KEEPSQNDISPK 12 1 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 KEEPSQNDIS(1)PK;KEEPSQNDIS(1)PK;KEEPSQNDIS(1)PK;KEEPSQNDIS(1)PK 165.49 3.5497000000000005e-18 72087000.0 366179.0 354123.0 270616.5 305725.0 291643.0 333485.0 326595.0 286737.0 279107.7 333454.0 True False 482616.30500364344 468586.33449730166 267027.9483923198 235244.8246541644 251153.40357462096 312632.1302316977 355661.32230165065 242428.38521076555 293860.76321233745 321779.87695549836 1.4998337048602592 1.4562325616219514 0.8298466359015026 0.7310737603604044 0.7805130822688302 0.9715714145634229 1.1052938600969073 0.7533982158999116 0.9132353644755042 1.0 18.295714581964127 -5.257138241465714 23.822807352487168 0.87845167779106 1.4780333051262708 0.8161794483471767 0.11241714082082128 74.96360927021362 415193.916401833 0.030818071462244034 0.07559593558366669 5.531739988578679e-06 5.257138241465714 0.5995816273352108 KEEPSQNDIS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 KEEPSQNDISPK 12 1 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 KEEPSQNDIS(1)PK;KEEPSQNDIS(1)PK;KEEPSQNDIS(1)PK;KEEPS(0.001)QNDIS(0.999)PK 144.15 4.2823999999999995e-05 59426000.0 317710.0 319403.0 220418.0 337639.0 309071.0 254371.0 322519.0 362335.0 273923.0 223814.0 True False 371492.02794146695 351111.21897911036 225673.60105991978 318722.1814704077 248510.7562347378 241031.33696544688 291967.66548464634 352824.09017566656 277928.6056635971 264389.70648935024 1.405092629642262 1.3280063873941073 0.8535642482322209 1.205501476220467 0.9399411177331443 0.9116517438062808 1.1043079905094828 1.3344849724317027 1.0512081175701604 1.0 18.012306483786766 -5.097391187837309 6.822532953977405 1.061059753239756 1.3865657032819456 0.4706856387306755 0.13486336775091898 0.20272314133281907 11.912531290899725 0.035586328549387945 0.0968285120214267 7.991141340452663e-06 5.097391187837309 0.3255059500421895 KEEPSQNDIS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 KEEPSQNDISPK 12 1 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 KEEPS(0.006)QNDIS(0.994)PK;KEEPS(0.001)QNDIS(0.999)PK;KEEPSQNDIS(1)PK 154.13 6.6448e-05 42923300.0 149373.0 134781.0 95314.2 106632.0 116758.0 97445.0 116864.0 114325.0 93782.0 86702.0 True False 147242.91362834667 134468.92287542025 87477.83439945184 114474.07299392413 109890.52399506007 93277.5045053897 122914.64610005653 119636.95686393196 83219.28359175919 101688.32517684695 1.4479824834588964 1.3223634339690846 0.8602544515048159 1.1257346681129952 1.0806601820213737 0.9172882368076185 1.2087390158732059 1.1765063162941312 0.8183759880697404 1.0 16.633794527513125 -5.085130138181843 5.360812497116179 1.0390308889360447 1.4208810271048433 0.5793772482704712 0.12462497989614385 0.13833493402084004 6.433968663630549 0.03134251408888723 0.0898692752353324 8.219962983647183e-06 5.085130138181843 0.38185013816879865 KEES(ph)DEEETASK ddPTM_PC-9_AZD4547_30min_R2 3 KEESDEEETASK 12 1 Q9BY89;A0A1B0GVJ7;Q9BY89-2 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 KEES(0.995)DEEET(0.005)ASK;KEES(1)DEEETASK;KEES(0.994)DEEET(0.006)ASK 186.42 9.768599999999999e-36 19133100.0 76830.0 81558.0 78234.0 98153.0 101022.0 90370.0 87652.0 84097.0 82791.0 91470.0 True False 101260.34183672434 107920.02854638339 77196.56604281256 75525.34229873329 86996.83906665086 84719.14961404148 95452.85819557618 71101.74100681022 87167.16323882354 88267.66314130121 1.1471963597203667 1.2226451307952058 0.8745735787661474 0.8556399887672377 0.9856026088215797 0.9597982613227318 1.0814023482503747 0.8055242257064025 0.9875322415558238 1.0 16.429597382880033 -5.257388281331212 24.99821993503611 0.9406495408785656 1.1849207663296342 0.6053421708007297 0.07785695183772005 217.6848101321779 1343261.4320826265 0.019973262314547775 0.04892967491930427 5.528556071929744e-06 5.257388281331212 0.2442712254510686 KEES(ph)DEEETASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KEESDEEETASK 12 1 Q9BY89;A0A1B0GVJ7;Q9BY89-2 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 KEES(1)DEEETASK;KEES(1)DEEETASK;KEES(0.979)DEEET(0.02)AS(0.001)K 113.65 0.00073837 3556000.0 67177.0 69313.0 55663.0 76338.0 75722.0 64613.0 76035.0 66642.0 61341.0 53898.0 True False 78548.73929377091 76193.93656634139 56990.21702310302 72061.02935113515 60884.81767492525 61224.58053531427 68832.4143542708 64892.718113035575 62237.99607922926 63669.28074366678 1.233699177630245 1.196714265912615 0.8950975471600858 1.1318021581122244 0.9562667736117233 0.9616031439369498 1.0810930098518132 1.019215504794131 0.9775200120416015 1.0 15.958309846089305 -5.14286043882518 6.44612512660104 1.0080979703022577 1.223461991820041 0.6458696044375687 0.0629793125507756 0.13416260865913301 6.501776913651386 0.015298040303014052 0.041688208306979495 7.196802111496363e-06 5.14286043882518 0.21536402151778322 KEES(ph)DEEETASK ddPTM_PC-9_Lapatinib_30min_R1 2 KEESDEEETASK 12 1 Q9BY89;A0A1B0GVJ7;Q9BY89-2 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 KEES(1)DEEETASK;KEES(0.999)DEEET(0.001)ASK 78.249 0.026577999999999997 13546000.0 72783.0 69573.0 59384.0 80486.0 76227.0 66338.0 67877.0 64672.0 62994.0 58409.0 True False 71745.10107323238 69411.90799305227 54501.676748869 86405.20893342518 71743.47772804808 63500.87838143096 71391.33893528834 67676.89721674335 55898.9523637721 68504.91782489969 1.0472985495233302 1.0132397818572803 0.795587798355976 1.261299358890979 1.0472748527547502 0.9269535735192153 1.0421345094926822 0.9879129756746402 0.8159845181721295 1.0 16.063919939402524 -8.021260680790743 21.158575982297453 0.9059774817857625 1.016991753785763 0.12355975024208621 0.11671913388341965 226.43488343412167 225338.9772726963 0.0760051692662312 0.029618480036141002 9.52224429543368e-09 8.021260680790743 0.11101427200000036 KEES(ph)PPPPK ddPTM_PC-9_Lapatinib_30min_R1 2 KEESPPPPK 9 1 E9PGM9;P78332;P78332-2 E9PGM9 RBM6 RNA-binding protein 6 1 KEES(1)PPPPK;KEES(1)PPPPK 88.18700000000001 0.0085475 100320000.0 279055.0 239854.0 231721.0 220721.0 255382.0 209261.0 244031.0 223466.0 225792.0 230756.0 True False 275075.62452758005 239298.63279958582 212669.79384892707 236953.55864367168 240360.93286033007 200311.39484121648 256665.73112714637 233849.04616274103 200360.92726483193 270641.86713695683 1.0163823780759669 0.8841892621088446 0.7857978371886811 0.8755244011221761 0.8881143756619767 0.7401345437062403 0.9483592979990124 0.8640534764135477 0.7403175620401716 1.0 18.04602550975531 -4.792949309786334 3.8287382735772795 0.8506645567594553 1.0307186479556467 0.26730251437829256 0.07921936117437926 0.29714479922148146 7.795658684125759 0.018783491655479864 0.14726991955107338 1.6108336383412345e-05 4.792949309786334 0.18005409119619142 KEESEES(ph)DDDMGFGLFD ddPTM_PC-9_AZD4547_30min_R2 4 KEESEESDDDMGFGLFD 17 1 P05387;H0YDD8;P05386-2;P05386 P05387;P05386 RPLP2;RPLP1 60S acidic ribosomal protein P2;60S acidic ribosomal protein P1 1 KEES(0.045)EES(0.955)DDDMGFGLFD;KEES(0.043)EES(0.957)DDDMGFGLFD;KEES(0.053)EES(0.947)DDDMGFGLFD;KEES(0.102)EES(0.898)DDDMGFGLFD 72.433 0.011565 30238900.0 184598.5 158140.4 186965.7 206733.8 216909.6 210030.7 206260.4 209076.0 196905.3 218756.4 True False 243296.98311267226 209256.1916959278 184486.41265678167 159074.5164153704 186795.4461722362 196897.44712672167 224617.17602066006 176768.10828852231 207313.3121678631 211097.8050202665 1.1525320364620297 0.9912760186011318 0.8739380906356179 0.7535583631487708 0.8848763072373153 0.9327309069263817 1.0640431623582993 0.8373753970182288 0.9820723249489018 1.0 17.68755205216101 -4.850665728820125 2.9297339126430706 0.9098499349242977 1.1749259799297553 0.42369479184896 0.08343015779230689 0.3317211963508038 4.484500704333637 0.02245994249477012 0.19437867464249767 1.4103739284192534e-05 4.850665728820125 0.26507604500545767 KEESEES(ph)DDDMGFGLFD ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KEESEESDDDMGFGLFD 17 1 P05387;H0YDD8;P05386-2;P05386 P05387;P05386 RPLP2;RPLP1 60S acidic ribosomal protein P2;60S acidic ribosomal protein P1 1 KEES(0.01)EES(0.99)DDDMGFGLFD;KEES(0.021)EES(0.979)DDDMGFGLFD 63.614 0.023947 22057500.0 109609.0 118945.0 109054.0 140485.0 143565.0 133909.0 140033.0 149910.0 122432.0 98916.0 True False 128163.6388235698 130753.07351988034 111654.26094959836 132614.08090851494 115434.46883997573 126886.57630667827 126768.06048887515 145975.02134277427 124222.336381412 116848.68778137496 1.0968342157454538 1.1189947957697277 0.9555456981982081 1.134921439226063 0.9878970062201704 1.0859050171285132 1.0848907497023796 1.2492653885501477 1.063104248237971 1.0 16.834282007086152 -7.3682270786807225 3.6533211939179746 1.1237446555466761 1.060577244909312 0.024712632161349224 0.07908917712665993 0.5436011267506392 13.247396623121977 0.03400370642201411 0.021988010326211754 4.2832450466646307e-08 7.3682270786807225 -0.06316741063736409 KEESEES(ph)DDDMGFGLFD ddPTM_PC-9_Lapatinib_30min_R1 5 KEESEESDDDMGFGLFD 17 1 P05387;H0YDD8;P05386-2;P05386 P05387;P05386 RPLP2;RPLP1 60S acidic ribosomal protein P2;60S acidic ribosomal protein P1 1 KEES(0.012)EES(0.988)DDDMGFGLFD;KEES(0.087)EES(0.913)DDDMGFGLFD;KEES(0.253)EES(0.747)DDDMGFGLFD;KEES(0.082)EES(0.918)DDDMGFGLFD;KEES(0.078)EES(0.922)DDDMGFGLFD 89.484 0.0024508000000000004 27364800.0 322808.8 301891.8 318183.0 305059.0 327315.0 311286.5 293695.3 277134.0 316123.0 307253.4 True False 318205.48731611576 301192.7880852768 292023.22196189844 327494.0565069915 308062.97522604937 297973.5020392734 308901.40557186055 290010.6573674076 280517.8988172325 360361.74080057896 0.8830168447105152 0.8358067851935321 0.8103613366755866 0.9087925254757382 0.854871481477632 0.8268733006375649 0.8571981167745659 0.8047764913198622 0.7784341872531598 1.0 18.45908632441391 -6.552556991765393 22.604758682882174 0.8414202895521631 0.8577352891613057 0.0 0.06073651737942385 445.1908486912078 339077.54575103807 0.01919513152433673 0.01919573381019634 2.801837916863379e-07 6.552556991765393 0.016314999609142622 KEET(ph)PGTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KEETPGTPK 9 1 Q99442 Q99442 SEC62 Translocation protein SEC62 1 KEET(0.595)PGT(0.405)PK 87.184 0.0378 5870700.0 29361.0 35696.0 21834.0 22544.0 31651.0 14472.0 21476.0 15282.0 12084.0 16451.0 True False 34331.23739381647 39239.6629733545 22354.60536590612 21280.932768634128 25449.2137586046 13713.062843500029 19441.637807224593 14880.863692617422 12260.705639318006 19433.43607395566 1.766606649650937 2.0191829599266176 1.1503166645792176 1.095067937941991 1.3095581070560742 0.7056427278898983 1.0004220423623347 0.7657350782428274 0.630907760864255 1.0 14.246253389509357 -5.292151151610206 0.6874663291382057 0.8149593237114865 2.2663711790756405 0.7613067918470615 0.20861571275785679 0.8156227711248536 0.4582492570240591 0.09912028741044229 0.8337696961393302 5.1032735501435e-06 5.292151151610206 1.451411855364154 KEFETSNGDSLLGLPEGALIS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 KEFETSNGDSLLGLPEGALISK 22 1 Q96L73-2;Q96L73-3;Q96L73 Q96L73-2 NSD1 Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific 1 KEFETSNGDS(0.002)LLGLPEGALIS(0.998)K 53.865 0.0074765 955730.0 772.9 795.41 1020.5 3506.8 955.01 1068.5 796.12 3138.8 2210.6 1132.8 True False 1018.6661226813002 1052.5107274096817 1006.967503217145 2698.36143951991 822.4233461725406 1001.6865260883386 866.9731377112021 2653.770582448551 2327.4478029706556 1093.141016797485 0.9318707349081368 0.9628316120578518 0.9211688956354435 2.468447709907685 0.7523488127652085 0.9163378838559406 0.7931027419052717 2.4276562142212508 2.1291377482012805 1.0 10.0942638074574 -7.75569322376633 24.99997830517581 1.9587977612722136 1.1253638369331707 0.2512592337822315 0.5805854128125394 172.79870098905673 751810.3981646698 0.28373680011512503 0.15806516719612854 1.755119842784102e-08 7.75569322376633 -0.833433924339043 KEFSPFGTITSAK ddPTM_PC-9_Lapatinib_30min_R1 1 KEFSPFGTITSAK 13 1 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YAR2;H0YAP2;H0YB86 A0A087WTT1 PABPC1 Polyadenylate-binding protein;Polyadenylate-binding protein 1 0 132.51 3.4965e-05 3958900.0 46035.0 46382.0 48676.0 38873.0 48202.0 42376.0 41763.0 36286.0 45254.0 41833.0 False True 45378.53245821492 46274.605328701575 44674.04717479368 41731.850096526556 45366.8531287782 40563.67726328076 43925.28379207163 37971.980028555656 40157.0179742538 49063.7783110313 0.924888665739226 0.9431520955306734 0.9105301041348736 0.8505633184622419 0.9246506219146621 0.8267540466642087 0.895269082491261 0.7739310207183573 0.8184656656420825 1.0 15.582370717005881 -5.704481900772586 0.895249518919925 0.8544574769109586 0.9443454026231477 0.1261041622164868 0.060464869812056656 1.300717302184885 1.8497717747564462 0.024619313682926865 0.0876474829611271 1.974777176555479e-06 5.704481900772586 0.08988792571218907 KEGDLIAAQAR ddPTM_PC-9_Lapatinib_30min_R1 1 KEGDLIAAQAR 11 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 103.21 0.0018971 3875300.0 36408.0 30811.0 44855.0 33460.0 35456.0 39932.0 36896.0 35948.0 46462.0 35666.0 False True 35888.81524359049 30739.6590225222 41167.195045307126 35920.7600192879 33370.54778917805 38224.20144603849 38806.29434648548 37618.275314626015 41228.96029344986 41830.82057804229 0.8579514995799328 0.7348567060780532 0.9841354885329812 0.858715165586384 0.797750255147871 0.9137808180149118 0.9276962251812858 0.8992956579573409 0.985612037338126 1.0 15.3522786785656 -7.717588716627987 0.44212880492612655 1.0089708832670217 0.8312547643981559 0.4166899511036739 0.06223667990374485 1.0313189811781287 0.5070844150933441 0.06918456313975131 0.055232823847402496 1.9160696126811418e-08 7.717588716627987 -0.17771611886886574 KEGITGPPADSSKPIGPDDAIDALSSDFT(ph)CGSPTAAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGK 38 2 P20810-6;P20810-7;P20810-10;P20810-9;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;H0YA91 P20810-6 CAST Calpastatin 1 KEGITGPPADSSKPIGPDDAIDALS(0.038)S(0.146)DFT(0.335)CGS(0.335)PT(0.146)AAGK 77.493 1.4751e-09 97050000.0 60507.0 60451.0 47651.0 78163.0 78535.0 69086.0 74680.0 76450.0 73001.0 59164.0 True False 70749.64003227587 66452.17577325898 48787.18055742385 73783.78051786499 63146.6305182147 65463.008541047704 67605.76976362128 74443.26850547049 74068.50152067652 69889.9648580336 1.0123004093075239 0.9508114063047856 0.6980570194379764 1.0557135157778492 0.9035149845401047 0.9366581979833828 0.9673172665195615 1.065149605622008 1.059787362479445 1.0 16.09279770083134 -7.558277580737728 2.849480948419772 1.046961122219344 0.9220793350667938 0.24522853081616747 0.08976380897477883 0.37325665516637474 6.152431820311519 0.048222382812085345 0.02611103720450622 2.765173710665107e-08 7.558277580737728 -0.12488178715255016 KEGITGPPADSSKPIGPDDAIDALSSDFT(ph)CGSPTAAGK ddPTM_PC-9_Lapatinib_30min_R1 1 KEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGK 38 2 P20810-6;P20810-7;P20810-10;P20810-9;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;H0YA91 P20810-6 CAST Calpastatin 1 KEGITGPPADSSKPIGPDDAIDALS(0.041)S(0.041)DFT(0.383)CGS(0.383)PT(0.152)AAGK 61.099 3.91e-05 38843000.0 65047.0 83700.0 100580.0 75230.0 108760.0 103580.0 92944.0 100520.0 91377.0 98118.0 True False 64119.41785184112 83506.19779251267 92310.7006500279 80762.665159923 102362.950630387 99150.12485677328 97756.18554151531 105190.52616630141 81085.16001753192 115077.5655659828 0.5571843437640027 0.7256514106968326 0.8021607008804778 0.7018106853643472 0.8895126528523447 0.8615938681803527 0.8494808267860358 0.9140836934544605 0.704613098293599 1.0 16.812247081135574 -3.9081007305123387 0.5295912144636074 0.868486259377611 5.77776764733202e-16 0.5743940892180242 0.08003293134328861 7.3250036514119925 0.7813393799494945 0.04195122624201964 4.810570990855695 0.00012356608003269524 3.9081007305123387 -0.8684862593776105 KEGITGPPADSSKPIGPDDAIDALSSDFT(ph)CGSPTAAGKK ddPTM_PC-9_AZD4547_30min_R2 1 KEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKK 39 3 P20810-6;P20810-7;P20810-10;P20810-9;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;H0YA91 P20810-6 CAST Calpastatin 1 KEGITGPPADSSKPIGPDDAIDALS(0.028)S(0.061)DFT(0.414)CGS(0.414)PT(0.082)AAGKK 42.903999999999996 0.006672399999999999 10706000.0 27784.0 18404.0 22341.0 41268.0 31635.0 29832.0 20453.0 28966.0 28091.0 29544.0 True False 36618.73405689903 24352.733090164533 22044.743742649927 31754.30018424422 27243.02630984841 27966.6003240686 22273.277377288876 24489.97027246234 29575.832911086898 28509.673552493732 1.2844318960536116 0.8541919305152621 0.7732373259925202 1.1138079194690282 0.9555713172122755 0.9809512645795403 0.7812533291999283 0.8590056363630375 1.0373964071047705 1.0 14.799163899467379 KEGITGPPADSSKPIGPDDAIDALSSDFTCGS(ph)PTAAGK ddPTM_PC-9_AZD4547_30min_R2 2 KEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGK 38 2 P20810-6;P20810-7;P20810-10;P20810-9;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;H0YA91 P20810-6 CAST Calpastatin 1 KEGITGPPADSSKPIGPDDAIDALS(0.006)S(0.023)DFT(0.087)CGS(0.803)PT(0.081)AAGK;KEGITGPPADSSKPIGPDDAIDALS(0.141)S(0.118)DFT(0.1)CGS(0.535)PT(0.105)AAGK 81.068 4.4427e-10 278210000.0 158571.0 152619.0 187219.0 225276.0 209955.0 199003.0 163393.0 202242.0 185948.0 201247.0 True False 208993.27951830282 201950.10712278972 184736.35373327855 173342.09867950456 180806.37233710193 186559.31095101283 177934.660465817 170990.14595882548 195776.83165963416 194201.4037848196 1.0761677075716354 1.0399003466862469 0.9512616805693713 0.8925893186208494 0.9310250534411187 0.9606486220754902 0.916237766555866 0.8804784240812553 1.0081123403029577 1.0 17.567194103752506 -5.212750526062656 3.0151417542884915 0.9346710729199816 1.0695546954454855 0.5821748662636703 0.039411378117900894 0.1657613451512824 2.955220531656226 0.010123926415642992 0.032621340670458965 6.127022482528662e-06 5.212750526062656 0.1348836225255039 KEGITGPPADSSKPIGPDDAIDALSSDFTCGS(ph)PTAAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGK 38 2 P20810-6;P20810-7;P20810-10;P20810-9;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;H0YA91 P20810-6 CAST Calpastatin 1 KEGITGPPADSSKPIGPDDAIDALS(0.081)S(0.081)DFT(0.107)CGS(0.618)PT(0.113)AAGK 60.254 3.3513e-05 106810000.0 112630.0 107060.0 101630.0 130080.0 145910.0 141800.0 137780.0 158060.0 129760.0 106050.0 True False 131696.03445609985 117688.20926510928 104053.24463392141 122792.0393250498 117319.9829236992 134363.75837536648 124728.48095918249 153911.0924784133 131657.4945181982 125276.02550866168 1.051246907948834 0.939431218281843 0.8305918407886199 0.980171895033179 0.936491898169196 1.0725416761092605 0.995629295012705 1.22857579376009 1.0509392677778981 1.0 16.934750822144075 -6.896080298319414 1.694368365843817 1.0918951259240615 0.9391051367287437 0.34229514834752306 0.08061518656230389 0.36934717361409813 2.1749135122073304 0.036113745060932234 0.02964797823975856 1.270339205760623e-07 6.896080298319414 -0.15278998919531772 KEGITGPPADSSKPIGPDDAIDALSSDFTCGS(ph)PTAAGK ddPTM_PC-9_Lapatinib_30min_R1 1 KEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGK 38 2 P20810-6;P20810-7;P20810-10;P20810-9;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;H0YA91 P20810-6 CAST Calpastatin 1 KEGITGPPADSSKPIGPDDAIDALS(0.009)S(0.028)DFT(0.077)CGS(0.614)PT(0.273)AAGK 66.959 1.1458e-06 45644000.0 85751.0 93155.0 129530.0 110350.0 121080.0 120460.0 123470.0 117750.0 132640.0 106670.0 True False 84528.17501519252 92939.30532092624 118880.54340025956 118465.50711680892 113958.31245243897 115308.20660597502 129862.67245665015 123221.09486750916 117700.68643887891 125107.76737115918 0.675642902046373 0.7428739819583043 0.9502251210955974 0.9469076909138299 0.9108811934462635 0.9216710443236378 1.0380064738217614 0.9849196213529029 0.9407943960001655 1.0 16.932811837081886 -5.1931739118150535 2.884828513372191 0.9623025050260844 0.6822975893228378 0.8891290604182444 0.03601718105706971 0.08742028904993734 1.3920490035589317 0.010482149249005021 0.03588096837320077 6.409528576968828e-06 5.1931739118150535 -0.2800049157032466 KEGSYSSLS(ph)PPTLTPVMPVNAGGK ddPTM_PC-9_AZD4547_30min_R2 1 KEGSYSSLSPPTLTPVMPVNAGGK 24 1 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 KEGS(0.011)Y(0.009)S(0.011)S(0.011)LS(0.831)PPT(0.091)LT(0.036)PVMPVNAGGK 46.35 0.017705000000000002 8254100.0 23496.0 27874.0 31585.0 45466.0 40117.0 31883.0 25445.0 43503.0 34897.0 29157.0 True False 30967.239252839732 36883.72539422119 31166.162262727616 34984.51614269767 34547.44701982578 29889.350969840416 27709.55570650347 36780.61094949005 36741.5841763625 28136.22230470009 1.100618232166396 1.3108982789086028 1.1076882292588859 1.2433977725877432 1.2278637354260136 1.0623086015654444 0.9848356828583434 1.3072334498631657 1.3058463847232578 1.0 14.780141018424759 -6.71066038879886 24.999549387844485 1.1420451212477443 1.201854625802088 0.0693114698896411 0.11780347217446256 369.694730792799 182006.75995285725 0.04028812660269282 0.04028807043526745 1.94688191642348e-07 6.71066038879886 0.05980950455434364 KEGSYSSLS(ph)PPTLTPVMPVNAGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KEGSYSSLSPPTLTPVMPVNAGGK 24 1 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 KEGS(0.047)YS(0.047)S(0.052)LS(0.825)PPT(0.025)LT(0.003)PVMPVNAGGK 75.10300000000001 0.00010604 8592500.0 28995.0 32747.0 39131.0 44857.0 45277.0 38194.0 34951.0 43161.0 40229.0 34420.0 True False 33903.28082264597 35997.90574261651 40064.03144514392 42343.807718356176 36405.296873664025 36191.0394033057 31640.18825667289 42028.069482859646 40817.27301920922 40660.07353142992 0.8338224178674688 0.8853379400504626 0.9853408507531284 1.0414100133297777 0.8953573791627064 0.8900878985211452 0.7781635769107812 1.0336446993971191 1.0038661879855624 1.0 15.311325203766364 KEGSYSSLS(ph)PPTLTPVMPVNAGGK ddPTM_PC-9_Lapatinib_30min_R1 1 KEGSYSSLSPPTLTPVMPVNAGGK 24 1 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 KEGS(0.001)YS(0.002)S(0.004)LS(0.84)PPT(0.104)LT(0.05)PVMPVNAGGK 81.765 4.0423e-05 4489400.0 23692.0 16497.0 22056.0 16501.0 20485.0 19585.0 19997.0 17302.0 18974.0 14012.0 True False 23354.1477354193 16458.802210072663 20242.640818622112 17714.538585722352 19280.11257505957 18747.395204864864 21032.346813927546 18105.914084056396 16836.94831492224 16433.955530183604 1.4210910874454814 1.001511911106454 1.2317570642955218 1.0779229962735843 1.1731875834547891 1.1407719322613632 1.279810376467081 1.1017380478365035 1.0245219590620454 1.0 14.004392147540056 -14.522878347206857 0.0573491123713234 0.3625082145999201 1.4353124206398862 0.25475410967730383 0.11096995902246114 699.3287087058375 2.9287906584159757 62.97805647481654 11.293365431188132 3.0000027497954438e-15 14.522878347206857 1.072804206039966 KEGSYSSLSPPT(ph)LTPVMPVNAGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KEGSYSSLSPPTLTPVMPVNAGGK 24 1 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 KEGS(0.006)Y(0.005)S(0.006)S(0.004)LS(0.166)PPT(0.579)LT(0.235)PVMPVNAGGK 59.547 0.0022115 8915200.0 16957.0 13831.0 17108.0 17001.0 21044.0 19029.0 18586.0 15617.0 14767.0 13747.0 True False 19827.48518398371 15204.050274105393 17515.919602451308 16048.489087985663 16920.579265618006 18031.08574136001 16825.39952901269 15207.070297579265 14982.93943858069 16239.222278807885 1.220962731069855 0.9362548287762902 1.0786181321817059 0.9882547829232482 1.0419574887954632 1.1103417042878032 1.0360963868922322 0.936440799718865 0.9226389774917584 1.0 13.98719492085492 -7.70011604056619 5.177086481960805 0.947045622348637 1.0546363076393124 0.3052934989115841 0.07318365417737752 0.23605333043590196 12.438111031383468 0.03446999627533708 0.01896761824686115 1.9947292655074774e-08 7.70011604056619 0.10759068529067539 KEIT(ph)GIGPSTTT(ph)ET(ph)ETIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KEITGIGPSTTTETETIAK 19 1 O75436;S4R3Q6;O75436-2 O75436 VPS26A Vacuolar protein sorting-associated protein 26A 3 KEIT(0.987)GIGPS(0.09)T(0.09)T(0.091)T(0.734)ET(0.504)ET(0.504)IAK 45.342 0.029162999999999998 9154500.0 2651.3 1242.7 48588.0 7980.3 23968.0 25256.0 9591.4 11779.0 19022.0 6689.1 True False 3100.11272443805 1366.0670432818138 49746.522191016105 7533.18966348168 19271.642455727615 23931.53089935303 8682.833156277427 11469.813730882122 19300.160763911565 7901.7808791135385 0.39233088994310816 0.1728809067450458 6.295608920580055 0.9533533995347631 2.4388986167241837 3.0286249727084043 1.0988450944303472 1.4515479366429689 2.4425077155615527 1.0 12.947962124776788 -7.2792388169446145 24.215730096688365 1.535854291221758 2.2593562467879025 0.041758830751908005 1.6663552378862037 2305.103287952964 3136024.1844106917 0.7085942959393697 0.4790459635684734 5.257280909384649e-08 7.2792388169446145 0.7235019555661444 KEKPELSEPSHLNGPSS(ph)DPEAAFLSR ddPTM_PC-9_AZD4547_30min_R2 1 KEKPELSEPSHLNGPSSDPEAAFLSR 26 2 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 KEKPELSEPSHLNGPS(0.3)S(0.679)DPEAAFLS(0.022)R 60.516999999999996 0.0007406000000000001 5765900.0 8544.1 8374.0 12632.0 19664.0 19319.0 15257.0 13282.0 15712.0 10723.0 15202.0 True False 11260.946071679777 11080.731737504779 12464.491426397826 15130.768605771504 16636.89032021374 14302.977378128006 14464.072269356613 13284.071425841606 11289.795888561632 14669.782607128673 0.7676286945252756 0.7553439634558851 0.849671175109357 1.03142418745993 1.134092492422428 0.9749958647088321 0.9859772742867985 0.9055397603088071 0.7695953096861462 1.0 13.84055987128732 -5.556232491707695 4.149320717234746 0.9747126908189098 0.7674745774498754 0.48829825875186783 0.08762985396055085 0.18601386712120685 7.123470342436936 0.026607944586451895 0.050670284509746505 2.778225596696399e-06 5.556232491707695 -0.20723811336903442 KEKT(ph)PELPEPSVK ddPTM_PC-9_AZD4547_30min_R2 1 KEKTPELPEPSVK 13 2 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 KEKT(1)PELPEPSVK 61.11 0.025842 69624000.0 303400.0 281000.0 232810.0 304450.0 341530.0 284240.0 305310.0 258590.0 305040.0 333750.0 True False 399874.8888879634 371827.7547455031 229722.78728464848 234263.75620561084 294114.4547369224 266466.4278664951 332481.9985361598 218630.85730705087 321163.7916484977 322065.514085593 1.2415948662597 1.1545096835381299 0.7132796814240618 0.7273792006906777 0.9132131255094817 0.8273671542358251 1.032342750139335 0.6788397010707174 0.9972001894097371 1.0 18.296994663498765 -5.136874298959977 5.366085132696414 0.8524523316420047 1.2193296612438624 0.5566387800723525 0.12082726285018633 0.14636434021271913 5.683638483272727 0.029818190321859405 0.0837751919256906 7.2966867305438365e-06 5.136874298959977 0.3668773296018577 KEKT(ph)PELPEPSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KEKTPELPEPSVK 13 2 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 KEKT(1)PELPEPSVK;KEKT(1)PELPEPSVK;KEKT(1)PELPEPSVK 62.891000000000005 0.022489 74175300.0 164039.0 152702.0 116367.0 197362.0 173936.0 168735.0 178504.0 201257.0 154207.0 135078.0 True False 191807.56278206658 167861.2453876397 119141.63060430522 186304.44699623706 139854.48941002373 159886.23955900894 161594.80886295458 195974.21699941767 156461.98564401787 159566.5721231405 1.202053539346857 1.051982524623629 0.7466578307664677 1.1675656405808006 0.8764648356429905 1.0020033483931818 1.0127109125227611 1.2281658645156626 0.9805436286697519 1.0 17.283798924973773 -7.553340262005437 24.99782053576514 1.0867005403579646 0.9998985721588051 0.03360019682673665 0.13779024520281044 575.2464533570133 472061.45983156405 0.06319448733532487 0.03648584126080532 2.7967892263774892e-08 7.553340262005437 -0.08680196819915953 KEKT(ph)PELPEPSVK ddPTM_PC-9_Lapatinib_30min_R1 1 KEKTPELPEPSVK 13 2 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 KEKT(1)PELPEPSVK 67.118 0.016933 67738000.0 77342.0 86556.0 69089.0 76067.0 91446.0 69014.0 79525.0 81595.0 66425.0 56846.0 True False 76239.08889721433 86355.58489998487 63408.76911125231 81661.22093207327 86067.32606975331 66062.43209949165 83642.4153811866 85386.20157719242 58943.51701374034 66671.75535746629 1.1434990497618065 1.2952349077503966 0.9510589419954641 1.2248248226590057 1.2909113553152458 0.9908608487251055 1.2545404711894965 1.2806952677244965 0.8840852726572093 1.0 16.024788090947784 -8.268338159769332 24.99677817406037 0.9420426130725249 1.1767436121887114 0.39143788901754284 0.11813291999890377 598.4800446171361 2168479.047615435 0.10257059642055145 0.028833411311068587 5.390907005826712e-09 8.268338159769332 0.23470099911618647 KELEEDFIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KELEEDFIK 9 1 Q14019;H3BT58 Q14019 COTL1 Coactosin-like protein 0 ; 70.41199999999999 0.023883 4950800.0 28996.0 32255.0 32433.0 30011.0 36927.0 27749.0 34500.0 31554.0 30054.0 28078.0 False True 33904.45010289507 35457.063234131245 33206.325722837435 28329.58096697478 29691.419432687504 26293.79359067734 31231.91024163011 30725.740934226567 30493.482893418022 33168.3191346743 1.0221937977993951 1.069003921789461 1.0011458701904314 0.8541156653717469 0.8951740759647954 0.7927381994823397 0.9416187210095956 0.926358095189266 0.9193556890719858 1.0 15.0175182823141 -5.607136628390089 4.92927494251728 0.8980813823147 1.0435336167645943 0.5536982751775372 0.052762206373626205 0.13886476797308775 5.8616239036791775 0.014477155703757169 0.025850014716064122 2.4709466666249646e-06 5.607136628390089 0.1454522344498943 KELQAEATVS(ph)GSPEAPGTNVVSEPR ddPTM_PC-9_AZD4547_30min_R2 1 KELQAEATVSGSPEAPGTNVVSEPR 25 1 K7EJ02;Q9BZV1-2;Q9BZV1 K7EJ02 UBXN6 UBX domain-containing protein 6 1 KELQAEATVS(0.718)GS(0.282)PEAPGTNVVSEPR 128.68 7.6132e-08 7905700.0 17698.0 16026.0 19313.0 23736.0 21601.0 19556.0 16585.0 19055.0 21590.0 21767.0 True False 23325.595858731587 21206.091094489086 19056.897001109974 18264.031917544355 18602.074010400996 18333.160228529283 18061.03287059776 16110.487590339362 22731.203323141435 21004.94395535916 1.1104812232922117 1.0095761807104755 0.9072576933130944 0.869511099689676 0.8856045533820576 0.8728021492221977 0.8598467536491429 0.7669855070586353 1.082183478872927 1.0 14.358441316031662 -4.9971293333288775 1.959685564483859 0.8907436350583129 1.1303204815490642 0.3875332326974592 0.08112940520557571 0.4527471339203781 2.5980478580275324 0.021202500393258494 0.16908316583767752 1.006631848244475e-05 4.9971293333288775 0.23957684649075128 KELQAEATVSGS(ph)PEAPGTNVVSEPR ddPTM_PC-9_AZD4547_30min_R2 1 KELQAEATVSGSPEAPGTNVVSEPR 25 1 K7EJ02;Q9BZV1-2;Q9BZV1 K7EJ02 UBXN6 UBX domain-containing protein 6 1 KELQAEATVS(0.044)GS(0.956)PEAPGTNVVSEPR 87.025 4.0404e-06 5438700.0 9797.3 10553.0 18174.0 17846.0 17366.0 18437.0 15291.0 20252.0 13473.0 14800.0 True False 12912.637603500461 13964.050874837334 17933.00088531935 13731.880417951497 14955.030658979851 17284.131475424147 16651.869377407904 17122.518744662946 14185.155274325349 14281.856504769401 0.9041287874015754 0.977747596761952 1.2556491433260555 0.9614912748469192 1.047134919328285 1.2102160156595987 1.1659457138395868 1.1989000686951945 0.993229085419549 1.0 13.80189590766544 -6.576200855244177 14.753338394327955 1.1293014290107195 1.0336931713737127 0.11994827946930575 0.11061776526216384 4.1308744430212165 1140.3979118747502 0.03680640129691247 0.03680603019967643 2.6533781271526387e-07 6.576200855244177 -0.09560825763700675 KELS(ph)PAGSISK ddPTM_PC-9_AZD4547_30min_R2 1 KELSPAGSISK 11 1 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;O95453-4 O95453 PARN Poly(A)-specific ribonuclease PARN 1 KELS(0.998)PAGS(0.002)ISK 68.413 0.017087 61445000.0 282620.0 318130.0 360110.0 450050.0 350500.0 328610.0 344840.0 343390.0 276550.0 349620.0 True False 372487.281138813 420959.30112877843 355334.7061083063 346297.92570318707 301839.1250703922 308061.96475235285 375530.0919564022 290326.9658171941 291167.86841198517 337379.91021604615 1.1040588661615487 1.2477307877022406 1.053218331467225 1.0264331550785881 0.8946564864431469 0.9131010929343152 1.1130778110526083 0.8605342435217289 0.8630266936330963 1.0 18.364014543217607 -5.674701380904557 1.959922692483007 0.943021017227026 1.1746869264120394 0.5549722272443645 0.08027515553632815 0.24444022796711118 1.898378034333099 0.024514252960978665 0.053576092995167204 2.1149427659186554e-06 5.674701380904557 0.2316659091850134 KELS(ph)PAGSISK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KELSPAGSISK 11 1 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;O95453-4 O95453 PARN Poly(A)-specific ribonuclease PARN 1 KELS(0.807)PAGS(0.192)IS(0.001)K;KELS(1)PAGSISK 101.61 0.0053809 19830800.0 97358.0 99263.0 91307.0 112867.0 132715.0 103199.0 118905.0 104964.0 97423.0 84733.0 True False 113838.78649184896 109117.17463368669 93484.10516372601 106543.42790975118 106710.44845259881 97787.06276854337 107641.45760234888 102208.80621855105 98847.62706879167 100094.42215394098 1.1373139885534254 1.0901424103919508 0.9339591872557236 1.064429222098829 1.0660978519710385 0.9769481721783759 1.0753991609722355 1.0211238950094366 0.9875438105508837 1.0 16.61100205545327 -5.014985257438277 19.76827636070276 1.0201533907262241 1.1255219748802117 0.4731766012047671 0.04246057802780452 32.685921649074075 43127.538291490164 0.010476196713796232 0.03042366992892109 9.660836731123216e-06 5.014985257438277 0.10536858415398753 KELS(ph)PAGSISK ddPTM_PC-9_Lapatinib_30min_R1 2 KELSPAGSISK 11 1 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;O95453-4 O95453 PARN Poly(A)-specific ribonuclease PARN 1 KELS(0.997)PAGS(0.002)IS(0.001)K;KELS(0.999)PAGS(0.001)ISK 82.34899999999999 0.006437999999999999 93167000.0 661730.0 484560.0 570390.0 486760.0 574760.0 498760.0 507290.0 540550.0 494690.0 462040.0 True False 652293.6088535787 483438.0310912784 523494.7359690736 522557.9541837583 540953.7468216368 477429.197466347 533554.9940109669 565665.9263747924 438972.80288336106 541902.9983703997 1.2037091708574108 0.8921117479420929 0.9660303366899924 0.9643016476291597 0.998248299877252 0.8810233545524991 0.9845950209086556 1.0438508885831081 0.8100578963457143 1.0 19.0476751040707 -4.753038389368761 24.991375412160313 0.9518345962539944 1.2037096419888955 0.575435121695137 0.06561480880544418 221.55688491085692 659039.4856670658 0.015374341710792645 0.1723033595775822 1.7658817190463697e-05 4.753038389368761 0.25187504573490116 KELSDIAHR ddPTM_PC-9_AZD4547_30min_R2 1 KELSDIAHR 9 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 59.757 0.028914 8507700.0 33923.0 32911.0 62556.0 84997.0 76054.0 58343.0 55782.0 68167.0 53665.0 54786.0 False True 44709.80835776651 43548.8371403176 61726.466566635696 65402.254840559384 65495.2148875996 54694.802986964845 60746.48993594718 57633.3564718269 56501.62234073108 52867.95881556059 0.8456881892063346 0.8237283624330112 1.1675591028959451 1.2370868160188848 1.2388451598082588 1.034554845928089 1.1490227974919984 1.0901377273310524 1.0687309214612803 1.0 15.690106006182893 -5.258610830786899 24.986375664196167 1.1324092700041741 0.8347082428562341 0.6993007292191198 0.07549049628039635 126.91853570808995 1121137.0826652118 0.020226397867922307 0.048809340672757294 5.513014937657916e-06 5.258610830786899 -0.29770102714794 KELSDIAHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KELSDIAHR 9 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ; 59.931000000000004 0.028627 10843000.0 94388.0 110366.0 147681.0 150460.0 173425.0 163311.0 150121.0 141316.0 136924.0 115469.0 False True 110366.0241520228 121322.40709651637 151202.27512331167 142030.2139979016 139443.616191779 154746.68366741535 135900.45209808016 137606.60473667845 138926.25446524157 136402.61564789896 0.8091195585054956 0.8894434063470624 1.1084998216868187 1.04125726125758 1.022294297872776 1.134484723275898 0.9963185196454366 1.0088267302137914 1.018501396071883 1.0 17.057511784092675 -5.083792295380423 4.2963705723527585 1.0421481863107545 0.8235994258349185 0.7596458676339553 0.044141519280582284 0.09510703530633446 3.1051077205349658 0.011524715750518034 0.03617428615039623 8.245323595653416e-06 5.083792295380423 -0.21854876047583593 KELSDIAHR ddPTM_PC-9_Lapatinib_30min_R1 3 KELSDIAHR 9 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ;; 62.463 0.024428000000000002 14107900.0 215652.0 162327.0 214471.0 174102.0 199731.0 202318.0 172196.0 178762.0 202636.0 157001.0 False True 212576.76293426685 161951.14180484106 196838.02226200106 186906.04186724618 187983.21526625424 193665.33076629293 181111.46631850128 187067.93512276514 179812.99982832215 184138.41365931786 1.1544400688036989 0.8795076409448905 1.0689677311230632 1.0150301512483366 1.020879954000526 1.0517378037404037 0.9835615650169722 1.0159093445263807 0.9765099864550896 1.0 17.490431097402833 -7.280644127276419 24.285631340337744 0.9953210037981898 1.0252761636222207 0.07066876086710949 0.06450051799847378 2065.965646288716 2612530.1097892006 0.02525113438708948 0.01706055151793886 5.240296648769059e-08 7.280644127276419 0.029955159824030964 KEMEAFLVS(ph)VGATTVHFSDK ddPTM_PC-9_Lapatinib_30min_R1 1 KEMEAFLVSVGATTVHFSDK 20 1 A0A096LNL1;Q7L775 A0A096LNL1 EPM2AIP1 EPM2A-interacting protein 1 1 KEMEAFLVS(0.985)VGAT(0.011)T(0.003)VHFS(0.001)DK 45.395 0.030851 7259100.0 13421.0 15585.0 17622.0 14395.0 13624.0 18619.0 15678.0 13082.0 14605.0 11907.0 True False 13229.614078890028 15548.91389003954 16173.187182887135 15453.656320312299 12822.663105814578 17822.708773008875 16489.730126956838 13689.837478188978 12960.031102531855 13965.1090849198 0.9473333862587586 1.1134115598731704 1.1581139169440304 1.1065904481190127 0.9181928352898516 1.2762312606820019 1.1807806173718502 0.9802886175068927 0.9280293496974343 1.0 13.769539222458983 -7.878013884723178 7.194039520146258 0.9612753007453766 1.102618942495877 0.26364090520201133 0.10013082410812627 0.3024968162818396 17.663357120120747 0.0565610324071822 0.026978948941225583 1.32429919567059e-08 7.878013884723178 0.1413436417505004 KENPLQFK ddPTM_PC-9_AZD4547_30min_R2 2 KENPLQFK 8 1 P15311;E7EQR4;E9PQ82;A0A2R8Y7M3;A0A2R8Y5S7;P35241;P35241-5;E9PNV3;A0A2R8Y5P0;P35241-3 P15311;A0A2R8Y7M3 EZR;RDX Ezrin;Radixin 0 ; 102.07 0.0027796999999999995 11966500.0 65971.0 62765.0 82425.0 87742.0 89764.0 84955.0 76480.0 95541.0 75838.0 78934.0 False True 86948.40571795564 83052.55881352843 81331.9906444617 67514.43750038667 77301.81803942558 79642.75042006081 83286.57183860819 80777.33376376866 79846.64185365438 76170.54468563966 1.1414964416599205 1.0903500710975778 1.067761704739327 0.8863588645587707 1.0148518480267503 1.0455846252478718 1.0934222957487936 1.0604799282602153 1.0482614005608886 1.0 16.216945591817158 -5.220430852384407 2.767320049829463 1.0256433470270971 1.1275851737083218 0.3316319119506054 0.05334854207922152 0.3641321899218695 5.3885641312495975 0.01572716566636347 0.0526244520064957 6.0196209863324744e-06 5.220430852384407 0.10194182668122465 KENPLQFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KENPLQFK 8 1 P15311;E7EQR4;E9PQ82;A0A2R8Y7M3;A0A2R8Y5S7;P35241;P35241-5;E9PNV3;A0A2R8Y5P0;P35241-3 P15311;A0A2R8Y7M3 EZR;RDX Ezrin;Radixin 0 83.647 0.009338899999999999 4332300.0 38915.0 35760.0 43238.0 48133.0 43545.0 47049.0 43816.0 41837.0 44955.0 37368.0 False True 45502.54089371502 39310.01647039322 44268.95790102815 45436.26405929148 35012.66984039802 44581.66761496914 39665.4312796309 40738.823079965674 45612.38182849564 44142.52259507478 1.030809709520135 0.8905249215362978 1.0028642519394095 1.0293082811801302 0.7931732892017498 1.0099483444551345 0.8985764507272765 0.9228929541174687 1.0332980343444365 1.0 15.429881456638991 -8.26424909999199 24.95084582754634 1.016649022624174 0.9452896712540992 0.13021841838316717 0.07158566248160299 484.68099357169973 4303921.720035912 0.05755869487522827 0.017307781369200494 5.441904298669435e-09 8.26424909999199 -0.07135935137007476 KENPS(ph)PLFSIK ddPTM_PC-9_AZD4547_30min_R2 1 KENPSPLFSIK 11 1 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 KENPS(0.994)PLFS(0.006)IK 85.469 0.0052473 6674400.0 49287.0 48200.0 51552.0 54110.0 46611.0 66300.0 45367.0 53254.0 57161.0 51825.0 True False 64959.24076671401 63779.70739762719 50868.38679652157 41635.775491166394 40139.8672144253 62154.25051909854 49404.575112475635 45024.81795517879 60182.41376350566 50010.62252430234 1.2989088615153208 1.2753232049177925 1.0171516415697965 0.8325386365853327 0.8026268258292444 1.242820972462302 0.9878816263178448 0.9003050888498593 1.20339261392438 1.0 15.609946943145905 -5.268654521482794 4.761563936209835 0.9888168342291879 1.292636877611446 0.4290118142157482 0.13334233665039183 0.1658485084111368 11.006952773887214 0.035958976763414766 0.08807780001315468 5.386981430848641e-06 5.268654521482794 0.3038200433822582 KENPS(ph)PLFSIK ddPTM_PC-9_Lapatinib_30min_R1 1 KENPSPLFSIK 11 1 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 KENPS(0.982)PLFS(0.018)IK 85.619 0.0052096 8360000.0 34467.0 53350.0 56543.0 45444.0 51483.0 56071.0 55958.0 53836.0 51788.0 49530.0 True False 33975.49425952632 53226.47135281426 51894.252802291856 48786.10335673998 48454.87115947237 53672.974037885 58855.23143540318 56337.41709798056 45955.09008818347 58091.19450542347 0.5848647897290927 0.9162571333912745 0.8933239063873432 0.8398192492355316 0.8341173145432319 0.9239433703308342 1.0131523707936214 0.9698099269196612 0.7910853009554321 1.0 15.826031875259769 -4.760422203180106 24.999999838158818 0.9068341392651014 0.5848644097031863 0.6647118023138783 0.06905792544051476 15.997052049181066 392981.2072330302 0.017813780050502655 0.10571565759912095 1.7361122313954984e-05 4.760422203180106 -0.32196972956191505 KENQWCEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KENQWCEEK 9 1 E5RJR5;P63208 E5RJR5 SKP1 S-phase kinase-associated protein 1 0 ; 73.84100000000001 0.018039 10165100.0 39994.0 40799.0 33689.0 45208.0 56327.0 37718.0 46933.0 48661.0 34879.0 29121.0 False True 46764.194282493634 44849.255088802376 34492.27352624398 42675.142326313544 45290.128696752756 35740.00168125581 42487.1664745051 47383.70031059134 35389.039390414866 34400.406778290846 1.359408177463914 1.3037419986878036 1.0026705134199492 1.2405417936291572 1.3165579403943013 1.0389412518171253 1.2350774439480636 1.3774168606777608 1.0287389802828704 1.0 15.070138004173137 -14.522878718804446 0.18163949200043786 0.11661635625306542 1.2555676460889509 0.22692411241324795 0.12963459350205725 227.2464755845182 2.187533117325366 72.29672536379631 0.4001423197329834 3.0000001828889875e-15 14.522878718804446 1.1389512898358856 KENQWCEEK ddPTM_PC-9_Lapatinib_30min_R1 3 KENQWCEEK 9 1 E5RJR5;P63208 E5RJR5 SKP1 S-phase kinase-associated protein 1 0 ;; 76.22800000000001 0.015706 11295100.0 81754.0 57178.0 66113.0 65006.0 60482.0 57663.0 55708.0 56422.0 65680.0 51614.0 False True 80588.17296815266 57045.607854005866 60677.44434356023 69786.75809365895 56924.56767218711 55196.887909018275 58592.28765866259 59043.57209863768 58282.42675893818 60535.411128668005 1.3312567217370097 0.9423510436355249 1.0023462831464105 1.152825375965932 0.9403515497927973 0.9118115641718745 0.9679010444667617 0.975355928006181 0.9627823727018041 1.0 15.885491695731819 -4.757145577479173 24.99737343505729 0.9849302151135166 1.3312572327599403 0.7369723252663366 0.06223985447574652 69.91838329087955 406993.53186645685 0.016504894524319136 0.1254683292496607 1.7492602303790624e-05 4.757145577479173 0.3463270176464237 KENSES(ph)EK ddPTM_PC-9_Lapatinib_30min_R1 1 KENSESEK 8 1 Q13427;E9PG73 Q13427 PPIG Peptidyl-prolyl cis-trans isomerase G 1 KENS(0.286)ES(0.714)EK 60.398 0.032072 4762800.0 11191.0 7608.1 11895.0 12837.0 9720.4 12749.0 7567.4 5116.0 12642.0 6105.5 True False 11031.414287821939 7590.483911890271 10917.039016027837 13781.075802976653 9148.665183041694 12203.754989370542 7959.202944427422 5353.708036876228 11218.124833838247 7160.827539932633 1.5405222687328843 1.0600009383778122 1.5245499148176023 1.9245088261274201 1.2775988713628148 1.7042380816066058 1.1114920587100607 0.7476381754791701 1.5665961470626037 1.0 12.805910606616502 -7.334611192697222 8.271609348965699 1.0833678986240285 1.4943111653463241 0.31573156985659856 0.28662496864052783 0.43212517788750693 45.1422739501317 0.11960445809918652 0.08046863097691348 4.6279515886382117e-08 7.334611192697222 0.41094326672229564 KEPAITSQNS(ph)PEAR ddPTM_PC-9_AZD4547_30min_R2 1 KEPAITSQNSPEAR 14 1 A0A1W2PRL9;A0A1W2PPZ5;P23193-2;P23193;E5RIS7 A0A1W2PRL9 TCEA1 Transcription elongation factor A protein 1 1 KEPAIT(0.005)S(0.005)QNS(0.991)PEAR 57.93600000000001 0.029913 7877600.0 17214.0 19628.0 30718.0 42867.0 30475.0 36815.0 23206.0 43843.0 17889.0 27907.0 True False 22687.693926556985 25972.367153539966 30310.65924921535 32984.675438547965 26244.072286790895 34512.95223017518 25271.289044021196 37068.07176191278 18834.57601888268 26929.984424229715 0.842469626760875 0.9644404818211424 1.125535714084704 1.224830839815513 0.9745297982117775 1.2815808463343499 0.9384071169860707 1.3764609432362511 0.6993905277545072 1.0 14.716925774963002 -4.998010607753603 3.047278637673249 1.0943550925817238 0.8456244647035808 0.13606875380325634 0.18353843072075213 0.4619538515810616 8.180442891035543 0.04356817197621214 0.21781358924982613 1.004591252580894e-05 4.998010607753603 -0.24873062787814304 KEPAITSQNS(ph)PEAR ddPTM_PC-9_Lapatinib_30min_R1 1 KEPAITSQNSPEAR 14 1 A0A1W2PRL9;A0A1W2PPZ5;P23193-2;P23193;E5RIS7 A0A1W2PRL9 TCEA1 Transcription elongation factor A protein 1 1 KEPAIT(0.002)S(0.015)QNS(0.984)PEAR 59.57899999999999 0.027070999999999998 6920500.0 30286.0 32447.0 35602.0 28509.0 29848.0 33566.0 28380.0 29640.0 31617.0 25684.0 True False 29854.116086227812 32371.870965037735 32674.940987694248 30605.64696323607 28092.399323425827 32130.460426167698 29849.37753559352 31017.18260613982 28055.96051823004 30123.44517822122 0.9910591537455308 1.0746403930066435 1.0847013279648943 1.0160075244435678 0.9325759107970888 1.0666263515368926 0.9909018493400666 1.0296691637570312 0.9313662614697891 1.0 14.878599158101729 -5.989296955454651 22.0112312592252 0.9949636167537586 1.0522127577906253 0.2557655495652117 0.04429108761159024 70.17091138463435 144302.03361974005 0.0121721369661433 0.018019681398968413 1.0249508608630537e-06 5.989296955454651 0.057249141036866735 KEPAVLELEGK ddPTM_PC-9_Lapatinib_30min_R1 1 KEPAVLELEGK 11 1 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 0 98.368 0.012245 0.0 52614.0 43378.0 45860.0 45762.0 48609.0 41747.0 52028.0 46712.0 44513.0 50993.0 False True 51863.7147117741 43277.56090613639 42089.567824719365 49127.49013755689 45749.91418897098 39961.57812701015 54721.75526504089 48882.41005053993 39499.477197329725 59807.07210609855 0.8671836437631852 0.7236194547253778 0.7037556988252477 0.8214327905971397 0.7649582662700828 0.6681747947152098 0.9149713125558756 0.8173349460047447 0.6604482681790059 1.0 15.868028470814536 -11.27177441864947 2.875919380612918 1.0432427246030478 0.7717613173444342 0.42273164546936226 0.08016743891842486 44094626.90567556 38744270.03358318 13599659.608085942 0.020204171456070213 5.348420950773622e-12 11.27177441864947 -0.2714814072586136 KEPVVGGTLS(ph)PLALANK ddPTM_PC-9_AZD4547_30min_R2 1 KEPVVGGTLSPLALANK 17 1 J3KTM2;O15534-4;O15534;J3KRL7 J3KTM2 PER1 Period circadian protein homolog 1 1 KEPVVGGT(0.161)LS(0.839)PLALANK 116.13 0.00054971 0.0 4766.3 7387.9 5514.3 10038.0 7373.7 6611.1 6239.1 9343.5 7485.3 7768.8 True False 6281.884254801245 9775.894196741288 5441.176779020384 7723.894185554028 6349.989034326828 6197.70687189763 6794.367813261772 7899.676767270307 7880.9576764571775 7496.816676638683 0.8379402252660962 1.3040060359491765 0.725798297292768 1.0302898575101824 0.8470247183867309 0.8267118083880464 0.9063003813917636 1.0537374872573586 1.0512405486738847 1.0 12.872062408304732 -7.764255099744165 24.962867830350127 1.0393667887646432 0.9295401767551218 0.10210758287100907 0.14835642920660141 177.0965175139388 1569993.3165259128 0.0751257731476658 0.03862036095024431 1.720857465538946e-08 7.764255099744165 -0.10982661200952137 KEQDY(ph)TK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KEQDYTK 7 1 Q15075 Q15075 EEA1 Early endosome antigen 1 1 KEQDY(0.972)T(0.028)K 60.358000000000004 0.033418 0.0 28147.0 27635.0 26637.0 28385.0 31073.0 26373.0 27831.0 21607.0 27816.0 22977.0 True False 32911.731171409396 30378.42016664755 27272.127101385042 26794.680475411624 24984.468709396886 24989.953452986898 25194.64620100892 21039.839144508875 28222.75637729807 27142.54821416808 1.2125512649630248 1.1192176919774386 1.0047740133385605 0.9871836742809994 0.9204909027795444 0.920692974580126 0.9282343721824033 0.7751607910390055 1.0397975958118086 1.0 14.72826855068823 -4.9802558938367225 0.8809323838191762 0.9170206536424919 1.3271837601063114 0.6630715851989066 0.06583284247376295 0.9657699646088638 0.718164132928121 0.02312500371314414 0.3607336797547746 1.046511743493457e-05 4.9802558938367225 0.4101631064638196 KEQSEVS(ph)VSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KEQSEVSVSPR 11 1 Q7L4I2;E9PI52 Q7L4I2 RSRC2 Arginine/serine-rich coiled-coil protein 2 1 KEQSEVS(0.993)VS(0.007)PR 101.38 0.0055198 5473400.0 7059.7 5722.0 7665.5 8320.0 9559.6 8190.4 9349.7 8120.5 6587.5 8354.5 True False 8254.767774569193 6290.0423446194045 7848.274591570635 7853.8573738039395 7686.46500416279 7760.881005624837 8464.028730033886 7907.345479380954 6683.829725174397 9869.104715814388 0.8364251887348647 0.6373468035596132 0.7952367329727946 0.7958024157164744 0.7788411639655514 0.7863814630711836 0.8576288299455381 0.8012221682793694 0.6772478271979562 1.0 13.268703499978178 -11.13436485941576 2.742009845454733 1.0193508624911274 0.7750252156912181 0.5298281637455807 0.06385850260240292 26108957.658876076 24686390.76146272 3618073.0896509844 0.015724176256767756 7.338970476129497e-12 11.13436485941576 -0.2443256467999093 KEQSEVSVS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 KEQSEVSVSPR 11 1 Q7L4I2;E9PI52 Q7L4I2 RSRC2 Arginine/serine-rich coiled-coil protein 2 1 KEQSEVSVS(1)PR;KEQSEVSVS(1)PR 149.69 0.00046463 18788400.0 22087.0 20444.6 33671.0 37475.0 33439.0 29726.0 26504.0 39000.0 26906.0 30589.0 True False 29110.206561860366 27052.917134056624 33224.50053975942 28835.7177329784 28796.57204915508 27867.22852082542 28862.80465494862 32973.44613084413 28328.196230312322 29518.088420566964 0.9861819690728211 0.9164860796069466 1.1255640970507421 0.9768829648496777 0.9755568056734607 0.9440729400826886 0.9778006029292273 1.117058993151793 0.959689388645317 1.0 14.849311675627154 KEQSEVSVS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KEQSEVSVSPR 11 1 Q7L4I2;E9PI52 Q7L4I2 RSRC2 Arginine/serine-rich coiled-coil protein 2 1 KEQSEVSVS(1)PR 126.09 0.00062935 4645400.0 6977.9 7420.6 7659.6 8170.9 7775.0 6760.3 6110.0 7742.2 8231.7 6246.7 True False 8159.1206501928355 8157.268126963091 7842.233913194764 7713.110963415215 6251.544563304499 6405.777967172011 5531.216567430728 7538.975453538972 8352.073039653596 7379.177261150007 1.1056951691822183 1.1054441217870707 1.0627517995105855 1.0452535141042494 0.8471872055734067 0.8680883708943052 0.7495709035953848 1.0216552857769488 1.131843394469693 1.0 12.849244257123058 -6.078189869945201 4.931429418046511 0.9250024090364584 1.0877303050830847 0.33477743568646856 0.0996261150250659 0.265565693806807 11.550220524865457 0.032322961246213394 0.042881537779126296 8.352377793681649e-07 6.078189869945201 0.1627278960466263 KEQSEVSVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 KEQSEVSVSPR 11 1 Q7L4I2;E9PI52 Q7L4I2 RSRC2 Arginine/serine-rich coiled-coil protein 2 1 KEQSEVS(0.004)VS(0.996)PR;KEQSEVSVS(1)PR 148.89 0.00043338 19629100.0 36443.0 34163.0 33741.0 30092.0 36154.0 28925.0 31257.0 33307.0 32097.0 24157.0 True False 35923.31613717232 34083.897672468476 30966.945224026505 32305.066063969254 34027.492801498825 27687.94517746828 32875.33451832442 34854.564813181496 28481.897863605966 28332.505262820814 1.267918802235696 1.2029962531126712 1.0929829514463276 1.1402121261179614 1.2010054347771084 0.9772501556296063 1.1603398362892006 1.2301970648151337 1.005272834131657 1.0 14.790170555231112 -1.5228787452803376 0.10351944381954038 0.9619745553453046 1.715379390845477 0.35650853393761806 0.07923649736074177 161.00054675886898 1.1795278171433359 0.9329119326757503 17.250692663574508 0.029999999999999995 1.5228787452803376 0.7534048355001725 KES(ph)APPSLRR ddPTM_PC-9_AZD4547_30min_R2 1 KESAPPSLRR 10 2 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;F8VWY3;H0YI41;C9JEB6 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 KES(0.99)APPS(0.01)LRR 59.975 0.022449 2601300.0 13492.0 9676.8 15606.0 21280.0 20587.0 18640.0 10632.0 15722.0 11985.0 13299.0 True False 17782.175348966357 12804.636359862216 15399.054243220753 16374.224772722626 17728.850407486938 17474.437853333307 11578.227403086841 13292.52615561875 12618.502632137557 12833.406057900553 1.3856162010878805 0.9977582180515028 1.1999195049034332 1.2759063882843682 1.381461034389435 1.3616367918613177 0.9021944253029387 1.0357753892962462 0.9832543734069182 1.0 13.647616500148185 -7.264385430258724 24.99848308300515 0.9832873231935157 1.257360890664682 0.6145915760944483 0.11107255692808102 201.47589595769458 1709594.7767896475 0.04810021619747303 0.03403239461484615 5.440196287486727e-08 7.264385430258724 0.2740735674711663 KES(ph)APPSLRR ddPTM_PC-9_Lapatinib_30min_R1 1 KESAPPSLRR 10 2 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;F8VWY3;H0YI41;C9JEB6 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 KES(0.998)APPS(0.002)LRR 56.295 0.027568000000000002 2722500.0 25551.0 17955.0 20005.0 12597.0 14127.0 15076.0 12813.0 12113.0 16826.0 10071.0 True False 25186.638054520452 17913.426300651914 18360.266121533143 13523.425402360122 13296.077634750623 14431.234623872488 13476.394445509508 12675.814200680556 14930.878694365012 11811.758931236025 2.1323359375304176 1.516575677249907 1.55440576026147 1.1449120728833722 1.1256644935064954 1.2217684688526191 1.140930366422513 1.073152125307904 1.2640690333495141 1.0 13.5279361971567 -1.5228787452820816 0.5827290122628087 1.118574211693379 57.285282084424146 0.8981880362134127 0.10240469380275403 43.36460806236555 0.35665975648753634 0.04581303836878627 3084.4775540624787 0.02999999999987953 1.5228787452820816 56.16670787273077 up KES(ph)APQVLLPEEEK ddPTM_PC-9_AZD4547_30min_R2 2 KESAPQVLLPEEEK 14 1 B1ALK7;A0A2R8YG42;Q14155-1;Q14155-5 B1ALK7 ARHGEF7 Rho guanine nucleotide exchange factor 7 1 KES(1)APQVLLPEEEK;KES(1)APQVLLPEEEK 115.91 6.9794e-05 20555100.0 270900.0 252390.0 186221.0 158595.0 177482.0 204413.0 191953.0 198829.0 210588.0 183831.0 True False 357040.5649299576 333970.1317445465 183751.5878653599 122033.37301832435 152841.68786232083 191631.02279578458 209036.44513776575 168104.54668588724 221719.25175607737 177395.13264380148 2.012685238928585 1.8826341330071215 1.035832185059563 0.6879183842284999 0.8615889601053347 1.0802496096697753 1.1783662946237543 0.947627729016843 1.249860965471223 1.0 17.436606900045433 -5.248232002758718 4.609892170804511 0.992145834544201 1.973471378406462 0.8649347605877472 0.14931735211914943 0.064533593153317 3.7725621833170337 0.0420702511041533 0.10911000020777635 5.646352626331858e-06 5.248232002758718 0.9813255438622609 KES(ph)APQVLLPEEEK ddPTM_PC-9_Lapatinib_30min_R1 2 KESAPQVLLPEEEK 14 1 B1ALK7;A0A2R8YG42;Q14155-1;Q14155-5 B1ALK7 ARHGEF7 Rho guanine nucleotide exchange factor 7 1 KES(1)APQVLLPEEEK;KES(1)APQVLLPEEEK 116.09 6.8578e-05 20692400.0 246870.0 222060.0 197532.0 190554.0 212779.0 195319.0 186887.0 165790.0 186966.0 221860.0 True False 243349.58852958662 221545.83371332558 181291.68145557074 204567.97682950908 200263.75755960957 186965.66168082706 196563.09441488588 173493.20864615095 165907.92024073747 260208.20539013174 0.9352110482631826 0.8514175538052713 0.6967177733067987 0.7861703535551428 0.769628910277264 0.7185233125162533 0.7554069792694571 0.6667476468931159 0.6375968044204859 1.0 17.989306931069777 -5.029145818517209 3.492881014849488 0.7427182857236118 0.9276419947664695 0.27165021953505364 0.09431551949867116 0.2661999170966906 6.580280368237704 0.023012535166541972 0.09331694898060945 9.350916554852685e-06 5.029145818517209 0.1849237090428577 KES(ph)GELY(ph)Y(ph)SIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KESGELYYSIEK 12 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 3 KES(0.629)GELY(0.909)Y(0.833)S(0.629)IEK 53.754 0.023938 22970000.0 147630.0 163070.0 192200.0 238530.0 245850.0 215170.0 207850.0 248580.0 195440.0 185560.0 True False 172620.8431745899 179258.51190791416 196782.77692255905 225165.93742469387 197677.45734899212 203886.10641486326 188160.94329631346 242055.0383922808 198297.94026384575 219200.55910784844 0.7875018379385569 0.8177830961631696 0.8977293567291511 1.0272142477242059 0.9018109176068899 0.9301349743115831 0.8583962744535554 1.104262869481039 0.9046415806187865 1.0 17.741891952575997 -5.359690042027571 2.9278310875917497 0.9575359469851692 0.7972634259218784 0.4627905962124603 0.06746498322998241 0.23215759667936486 3.7875664950443455 0.018121184469014586 0.04679009605855969 4.368274868019826e-06 5.359690042027571 -0.16027252106329082 KES(ph)KEETPEVTK ddPTM_PC-9_AZD4547_30min_R2 4 KESKEETPEVTK 12 2 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 KES(0.999)KEET(0.001)PEVTK;KES(0.992)KEET(0.007)PEVT(0.001)K;KES(1)KEETPEVTK;KES(0.955)KEET(0.044)PEVTK 78.324 0.005306399999999999 201536800.0 459977.0 376418.0 342178.0 331055.0 358165.0 340169.0 377274.0 330487.0 394536.0 362277.0 True False 606240.1178840417 498087.75724481395 337640.49614486657 254735.38449876377 308439.9721279232 318898.17865507136 410850.6551234195 279417.8279857503 415390.36749879277 349593.792498537 1.7341272382191362 1.4247614458054154 0.9658080417611521 0.7286610631103521 0.8822810322903946 0.9121963418626946 1.1752229700278183 0.7992642717960148 1.1882086478996365 1.0 18.41532004253881 -5.08702540285292 2.63499333990713 0.9424465736604357 1.720851243963682 0.7755260304682785 0.13865455783938122 0.13476972340168364 1.6937685868096015 0.037259382754044286 0.1683702311970571 8.184169157038815e-06 5.08702540285292 0.7784046703032463 KES(ph)KEETPEVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KESKEETPEVTK 12 2 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 KES(0.996)KEET(0.004)PEVTK 50.207 0.034736 6617700.0 41199.0 46347.0 42839.0 51170.0 48625.0 44371.0 49133.0 59459.0 43744.0 35626.0 True False 48173.17698265873 50948.023863347706 43860.444227812186 48303.110795378336 39097.28030748316 42044.106649318695 44478.766547884465 57898.26425201802 44383.67324448258 42084.7117847392 1.1446716619817114 1.2106064578496776 1.0421942403254596 1.1477590969957423 0.9290138544244624 0.9990351570986586 1.0568865666798601 1.3757552754112754 1.0546269978395584 1.0 15.361008616687528 -10.840585065541475 11.660708834309036 0.9999999988143945 1.1071440757236575 0.06875392050921014 0.11782809368970172 3.773037418872264e-09 1.5250746301668458e-10 0.1193427068195808 0.028944857776358898 1.4434938385257394e-11 10.840585065541475 0.10714407690926298 KES(ph)KEETPEVTK ddPTM_PC-9_Lapatinib_30min_R1 5 KESKEETPEVTK 12 2 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 KES(0.867)KEET(0.131)PEVT(0.002)K;KES(0.998)KEET(0.002)PEVTK;KES(0.993)KEET(0.007)PEVTK;KES(0.99)KEET(0.009)PEVTK;KES(0.993)KEET(0.007)PEVTK 56.122 0.024894 334169000.0 1066355.0 839057.0 612561.0 812848.0 742636.0 669508.0 597855.0 619314.0 672900.0 820249.0 True False 1051148.5821544454 837114.2150680078 562198.5991338398 872627.5535014399 698955.6105585517 640874.7035393758 628809.006573018 648089.589356912 597110.9160488663 962027.9467369084 1.0926383019535184 0.8701558181416724 0.5843890513168093 0.9070708979518686 0.7265439771571411 0.6661705678230568 0.6536286276358895 0.6736702312600789 0.6206793867830972 1.0 19.875719279069465 -4.905610615320789 3.3116070236972908 0.7183907578813054 1.1005331404952658 0.44746753180225374 0.12374800313405403 0.22610972232458837 4.36005323882208 0.03012087553504756 0.18681812010644994 1.2427660615372504e-05 4.905610615320789 0.3821423826139605 KES(ph)LSPGK ddPTM_PC-9_Lapatinib_30min_R1 1 KESLSPGK 8 1 E7ETM8;E7EUA0;Q0ZGT2-4;Q0ZGT2-2;Q0ZGT2;H7BXY5 E7ETM8 NEXN Nexilin 1 KES(0.995)LS(0.005)PGK 73.885 0.042207 5329600.0 11992.0 14186.0 13127.0 16935.0 18634.0 13344.0 17097.0 13961.0 12951.0 12568.0 True False 11820.991880936535 14153.153188585235 12047.748731685357 18180.4563935039 17537.98475585356 12773.308226383284 17982.199003736507 14609.679027136246 11492.321999924003 14740.362054192652 0.8019471867432354 0.9601631992858415 0.8173305843772388 1.2333792295374977 1.189793350487288 0.86655322165239 1.2199292620917521 0.9911343407593415 0.7796499134602465 1.0 13.847484340032189 -5.726530883095665 24.999970426345246 1.0461972509050477 0.8698485066442785 0.24381776644432362 0.14486232771088273 274.7558384538285 196766.3831287278 0.03989634533883781 0.06909880877477877 1.8770209368763821e-06 5.726530883095665 -0.17634874426076919 KES(ph)PTSSSFGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KESPTSSSFGK 11 1 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 KES(0.786)PT(0.014)S(0.154)S(0.037)S(0.009)FGK 73.46600000000001 0.028883 0.0 11457.0 9436.9 10839.0 11826.0 12312.0 10582.0 13087.0 9770.0 9307.4 10009.0 True False 13396.443813935333 10373.733065700611 11097.442867136402 11163.427560409302 9899.55198243151 10027.061291453667 11847.304618325035 9513.547852170677 9443.503117129141 11823.552468799595 1.1330303518579834 0.8773786975678572 0.9385878648926136 0.94416864896297 0.8372739080369285 0.8480582564261823 1.0020088843508006 0.8046268562071646 0.7987026861891964 1.0 13.529375947983894 -4.759407100812808 24.966295425992282 0.8914731702005281 1.1330306646764803 0.5046686714751307 0.07082552181640024 43.688419716144224 536568.4865895266 0.01754456774588267 0.11157999371490701 1.7401748960538914e-05 4.759407100812808 0.2415574944759522 KES(ph)SDSSCK ddPTM_PC-9_Lapatinib_30min_R1 1 KESSDSSCK 9 1 Q5M9Q1 Q5M9Q1 NKAPL NKAP-like protein 1 KES(0.712)S(0.143)DS(0.143)S(0.003)CK 77.533 0.033669 13000000.0 24271.0 86369.0 117070.0 116640.0 115330.0 95900.0 94090.0 87935.0 113920.0 88022.0 True False 23924.891089243727 86169.01788699543 107444.95650326852 125218.09469963337 108546.51614750405 91798.5805538187 98961.51981409432 92020.78112250043 101089.12996921789 103236.48541805727 0.23174840747783712 0.8346760114706835 1.0407653463615019 1.212924812313799 1.0514356015505928 0.8892067584641161 0.9585905546217364 0.8913591038077407 0.9791996459377356 1.0 16.65559340672089 -4.767946247762962 2.84675130408647 1.0012505245105219 0.0786467124701621 0.8747035207960691 0.08746666976460199 0.16158654466226408 1.7692526643145332 0.025720568999146827 0.35705712984565163 1.706293562352553e-05 4.767946247762962 -0.9226038120403598 down KESPTS(ph)SSFGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KESPTSSSFGK 11 1 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 KES(0.24)PT(0.011)S(0.416)S(0.27)S(0.063)FGK 70.563 0.035952 0.0 11049.0 9453.5 10491.0 10920.0 12685.0 10386.0 14774.0 14695.0 9613.3 8629.0 True False 12919.377472302645 10391.981003995028 10741.145227339055 10308.187803117667 10199.465310034422 9841.339876491937 13374.499765502707 14309.271820639507 9753.876325923196 10193.369392873587 1.2674295391801333 1.0194843925954744 1.053738446371661 1.0112640291760988 1.0005980276909319 0.9654648524139857 1.312078396261507 1.40378232840688 0.9568844167211629 1.0 13.315343389139949 -7.254948853921599 24.93634990652111 1.2018348133691927 1.0472283084698304 0.11286949324095108 0.14598911510587073 811.9191215761779 3119370.4843785455 0.05588106803457953 0.04219951741064516 5.559697289680375e-08 7.254948853921599 -0.15460650489936234 KESPTSS(ph)SFGK ddPTM_PC-9_Lapatinib_30min_R1 1 KESPTSSSFGK 11 1 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 KES(0.007)PT(0.01)S(0.376)S(0.606)S(0.001)FGK 146.36 0.00033471 4594800.0 10175.0 16947.0 17655.0 11557.0 19451.0 18770.0 15336.0 14999.0 15576.0 11148.0 True False 10029.902634133521 16907.76026272058 16203.47405027082 12406.940333021825 18306.930422137353 17967.250855007085 16130.023040375701 15695.908296541538 13821.66685744856 13074.916946223726 0.7671102367522372 1.2931447543614303 1.2392793099118444 0.9489115979895517 1.4001565361701764 1.3741770543480472 1.2336616061667869 1.2004595028096758 1.057113166706616 1.0 13.674514161841802 -4.754586998575862 24.999008347301515 1.2074173874063268 0.7671094834927601 0.44037105843861435 0.1437001498068925 221.7320906810001 808856.2520767902 0.03597456915313702 0.34485855118536307 1.7595961433370874e-05 4.754586998575862 -0.44030790391356667 KESYS(ph)VYVYK ddPTM_PC-9_AZD4547_30min_R2 1 KESYSVYVYK 10 1 U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 U3KQK0 HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 1 KES(0.007)YS(0.993)VYVYK 94.71700000000001 0.0028399000000000002 25416000.0 119630.0 171790.0 161800.0 204750.0 139700.0 138290.0 102940.0 139590.0 112170.0 119860.0 True False 157669.85154142094 227317.75796345173 159654.4262817581 157548.05085596617 120305.06639752886 129642.70443870498 112101.46057879609 118019.57295909057 118099.07720040626 115663.73788254481 1.3631744436751028 1.9653329740587346 1.380332584823476 1.3621213851479916 1.0401277755669394 1.1208586788916994 0.9692014336648348 1.0203679659647356 1.0210553399228244 1.0 16.81957710571956 -5.922941840387836 1.4527329680315357 1.0199041105648368 1.6592996386937884 0.7255452583838783 0.1531552035340376 0.193788261250685 0.8307179114968994 0.04935397867835492 0.09486319574464884 1.1941480110205966e-06 5.922941840387836 0.6393955281289516 KESYS(ph)VYVYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KESYSVYVYK 10 1 U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 U3KQK0 HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 1 KES(0.005)YS(0.995)VYVYK;KES(0.336)YS(0.662)VYVY(0.002)K 127.02 0.00048019 14400600.0 37029.0 35186.0 30759.0 43289.0 42400.0 39773.0 42646.0 35279.0 35295.0 29407.0 True False 43297.27834391301 38679.03354382706 31492.41121415708 40863.65767483159 34092.02437094674 37687.2338636351 38606.26214969735 34352.963631190316 35811.12260342017 34738.25631431609 1.2463860578422192 1.1134419987536026 0.9065628087146863 1.1763301331273541 0.9813971105077307 1.0848913521345542 1.1113471499658205 0.988908692490504 1.0308842873227906 1.0 15.08423771938292 -4.8770247001410265 3.875811123167038 1.040575230448192 1.248134644847964 0.4443017570167319 0.07206112568388048 0.20380556632528551 5.13212588293422 0.01719544019960012 0.09781827131106231 1.3273189654098376e-05 4.8770247001410265 0.2075594143997721 KESYS(ph)VYVYK ddPTM_PC-9_Lapatinib_30min_R1 2 KESYSVYVYK 10 1 U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 U3KQK0 HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 1 KES(0.028)YS(0.972)VYVYK;KES(0.037)YS(0.963)VYVYK 122.46 0.00078882 27150500.0 109116.0 127756.0 119848.0 76244.0 100143.0 105171.0 134515.0 133003.0 91986.0 81666.2 True False 107559.9858305761 127460.1888313054 109994.56006665871 81851.2381025281 94252.78562871313 100673.08149557524 141479.52851304994 139182.8049313234 81625.56802447754 95782.09385662856 1.1229654886390068 1.3307308673173734 1.1483833317666252 0.8545567841213322 0.9840334642276188 1.0510636951230963 1.4770978876785006 1.4531192556685928 0.8522007061847988 1.0 16.547468353686277 KESYSVYVYK ddPTM_PC-9_AZD4547_30min_R2 1 KESYSVYVYK 10 1 U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 U3KQK0 HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 0 85.92399999999999 0.007336700000000001 17062000.0 74520.0 83917.0 127920.0 136420.0 119460.0 108570.0 81940.0 123450.0 90337.0 108210.0 False True 98215.80988770927 111041.5291636242 126223.69721855695 104970.47666798958 102875.04102969762 101781.10073693101 89232.50126118674 104373.63909878755 95112.02939335928 104421.60083656044 0.940569854329619 1.0633961582089246 1.2087891413972949 1.0052563437740074 0.9851892731535167 0.9747130854298786 0.8545406366720282 0.9995406914145287 0.9108463060456964 1.0 16.67206065565785 -6.237169901358854 2.482257419472225 0.9460305772155186 1.0718235373607767 0.32221177179749994 0.0740084478222657 0.33192434720641995 4.035456873887616 0.024682751021272962 0.03185826076147905 5.792020611070611e-07 6.237169901358854 0.1257929601452581 KESYSVYVYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KESYSVYVYK 10 1 U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 U3KQK0 HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 0 ; 122.7 0.00032709 37489000.0 257230.0 239200.0 272300.0 315090.0 372150.0 301100.0 319030.0 276950.0 266510.0 273820.0 False True 300773.95847591676 262946.19518227206 278792.6647035012 297436.5288355633 299229.87900112825 285309.7859437438 288809.16882281954 269680.35595278116 270407.2045626155 323461.39844207297 0.9298604406107545 0.8129136782587729 0.8619039738475277 0.919542579943522 0.9250868278018521 0.8820520387221366 0.8928705873833687 0.8337327336482063 0.835979829015181 1.0 18.303234027152058 -5.7030063251364025 24.70944325787143 0.8917307356003416 0.8626946047462262 0.05269264228782322 0.05212032845706985 227.3782375439529 96147.87068324082 0.014018890777121729 0.02428141128353302 1.98149816672911e-06 5.7030063251364025 -0.029036130854115383 KESYSVYVYK ddPTM_PC-9_Lapatinib_30min_R1 1 KESYSVYVYK 10 1 U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 U3KQK0 HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 0 100.09 0.0026093 48517000.0 307510.0 267040.0 320010.0 219010.0 288890.0 248390.0 270900.0 270860.0 266420.0 331600.0 False True 303124.85100957315 266421.68528688856 293700.0130743225 235116.72599594243 271898.05817959295 237766.93872537088 284925.87647612026 283445.1444230439 236412.97407302557 388916.61817077355 0.7794083277677551 0.6850354879150539 0.7551747581672085 0.6045427606096855 0.6991165856024242 0.6113571074532157 0.7326143012768076 0.7288069760459115 0.6078757322969842 1.0 18.569101356008467 -11.383198847968046 2.874844403831547 1.123335344006617 0.6890718847915897 0.7075747464781315 0.05991648010201191 36657117.4149937 23217442.595238313 30841446.880590722 0.014329241990385074 4.138101625094606e-12 11.383198847968046 -0.4342634592150273 KET(ph)ESEAEDNLDDLEK ddPTM_PC-9_AZD4547_30min_R2 6 KETESEAEDNLDDLEK 16 1 A9Z1X7;Q8IYB3;Q8IYB3-2 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 KET(0.824)ES(0.176)EAEDNLDDLEK;KET(0.681)ES(0.319)EAEDNLDDLEK;KET(0.989)ES(0.011)EAEDNLDDLEK;KET(0.5)ES(0.5)EAEDNLDDLEK;KET(0.5)ES(0.5)EAEDNLDDLEK;KET(0.5)ES(0.5)EAEDNLDDLEK 121.35 6.4929e-05 79882300.0 181066.2 179279.1 150464.2 193065.1 203203.9 198872.8 194888.3 177330.1 190273.4 193123.9 True False 238641.48518907584 237227.56308111927 148468.94639643817 148556.9240210605 174992.5460396333 186437.25237759558 212232.98115133672 149927.8076853125 200330.86347315484 186362.69104334037 1.280521781763591 1.2729348441633621 0.796666680252596 0.7971387577061344 0.9389891563592907 1.0004000872376213 1.138816894965205 0.8044947561443261 1.074951549323604 1.0 17.507753542400046 -5.24452836376126 24.197448731651654 0.94050762330279 1.2767284559154577 0.587599651877539 0.11149154066541643 377.51968129465774 540177.7642289688 0.029370096137226083 0.0772064658214192 5.694710307752622e-06 5.24452836376126 0.33622083261266766 KET(ph)ESEAEDNLDDLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KETESEAEDNLDDLEK 16 1 A9Z1X7;Q8IYB3;Q8IYB3-2 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 KET(0.5)ES(0.5)EAEDNLDDLEK;KET(0.628)ES(0.372)EAEDNLDDLEK;KET(0.989)ES(0.011)EAEDNLDDLEK 117.35 0.00012233 93507000.0 81302.0 83479.0 52765.0 88253.0 87035.0 80133.0 93331.0 87918.0 71025.0 73011.0 True False 95064.82281230444 91766.24342650885 54023.117712376865 83308.47053008646 69981.11653597507 75930.68441391578 84490.01202207473 85610.24565682113 72063.6062589012 86247.31634524182 1.1022351400682053 1.063989551387027 0.6263744775098415 0.965925365104795 0.8114005107804825 0.8803831542997893 0.9796248231523782 0.9926134433462191 0.8355460704474067 1.0 16.396191946407086 -9.984898702788042 16.10383074262705 1.0000206659871589 0.9145467333949315 0.033963887279109706 0.13100384506792084 0.0 0.0 0.12806497478753864 0.031060318705357918 1.035383637039885e-10 9.984898702788042 -0.08547393259222735 KET(ph)ESEAEDNLDDLEK ddPTM_PC-9_Lapatinib_30min_R1 5 KETESEAEDNLDDLEK 16 1 A9Z1X7;Q8IYB3;Q8IYB3-2 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 KET(0.935)ES(0.065)EAEDNLDDLEK;KET(0.99)ES(0.01)EAEDNLDDLEK;KET(0.764)ES(0.236)EAEDNLDDLEK;KET(0.5)ES(0.5)EAEDNLDDLEK;KET(0.5)ES(0.5)EAEDNLDDLEK 103.45 0.0011565999999999998 273171500.0 293352.0 296476.0 233637.4 262215.6 266858.0 250020.0 239728.1 247435.8 241593.0 226120.0 True False 289168.7466858319 295789.5280374309 214428.63483844468 281499.8099495994 251161.93710301394 239327.22742508625 252140.04801939774 258932.57057679832 214382.25225292533 265204.5407140397 1.0903612204650446 1.1153260319036915 0.8085405863003499 1.0614441562413905 0.9470499125949454 0.9024250745508313 0.9507380504893809 0.9763504421140201 0.8083656926677052 1.0 18.016745951280775 -5.23214655098432 24.98748769144017 0.9358124732631782 1.1028437003316238 0.4555069094814288 0.07467456158242732 606.1111476708339 517025.54321111797 0.01797399005400333 0.04753760861345829 5.859404078373892e-06 5.23214655098432 0.16703122706844564 KET(ph)PPPLVPPAAR ddPTM_PC-9_AZD4547_30min_R2 1 KETPPPLVPPAAR 13 1 Q9BQA1-2;Q9BQA1 Q9BQA1-2 WDR77 Methylosome protein 50 1 KET(1)PPPLVPPAAR 74.96600000000001 0.016036 92348000.0 444170.0 472730.0 555010.0 619870.0 537990.0 570390.0 504730.0 627980.0 451520.0 427120.0 True False 585406.8206900684 625530.7277610025 547650.2047629076 476968.54839603207 463299.3748833678 534723.4231310516 549649.9922084302 530940.1205448068 475386.42540365114 412166.65880521084 1.4203158071714155 1.517664552427146 1.3287105908819423 1.15722254143183 1.1240583511203466 1.2973475940075028 1.3335624812588096 1.2881685337768383 1.1533839898202873 1.0 18.652868280813642 -1.5228787452803376 0.08697476086988068 0.8670426844996835 2.4172368840508263 0.5591712789412895 0.09675945492436712 154.61568380165056 0.9748504451220729 2.374180705855596 28.63397921271986 0.029999999999999995 1.5228787452803376 1.5501941995511428 KET(ph)PPPLVPPAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KETPPPLVPPAAR 13 1 Q9BQA1-2;Q9BQA1 Q9BQA1-2 WDR77 Methylosome protein 50 1 KET(1)PPPLVPPAAR;KET(1)PPPLVPPAAR;KET(1)PPPLVPPAAR 83.243 0.015580000000000002 209111000.0 673451.0 755704.0 702600.0 746162.0 865243.0 687658.0 699715.0 682433.0 655468.0 526124.0 True False 787452.9530364455 830725.2988462521 719352.6486253378 704356.9622298423 695704.8453488451 651596.0039272767 633432.9297020937 664519.8568475322 665052.9794763749 621506.116404709 1.2670075679893649 1.3366325397597614 1.157434544307708 1.133306565516055 1.119385355969401 1.0484144672567854 1.0191901784754411 1.069208877125215 1.0700666685688887 1.0 19.245409063724743 -5.606001519630684 0.8631686832568122 1.0436284496752275 1.3386375493444655 0.8707466609084046 0.036811087127226444 0.2944830569286045 0.3613607305789362 0.015316858247789082 0.06592601471764675 2.4774133889530536e-06 5.606001519630684 0.29500909966923805 KET(ph)PPPLVPPAAR ddPTM_PC-9_Lapatinib_30min_R1 2 KETPPPLVPPAAR 13 1 Q9BQA1-2;Q9BQA1 Q9BQA1-2 WDR77 Methylosome protein 50 1 KET(1)PPPLVPPAAR;KET(1)PPPLVPPAAR 88.95100000000001 0.005389100000000001 384930000.0 4328600.0 4335200.0 4154900.0 4081500.0 4455100.0 4439900.0 4183200.0 3826800.0 4089100.0 3582200.0 True False 4266873.370231987 4325162.110753898 3813300.160377803 4381667.125484875 4193059.777063604 4250015.826912413 4399785.627445198 4004607.098420238 3628542.4978680597 4201378.497018525 1.0155889009428547 1.0294626189530922 0.9076307128919426 1.0429117796919012 0.9980200022538258 1.0115765170713382 1.0472242933045595 0.9531650388704744 0.8636552265983715 1.0 22.002431331624237 -7.970563384886828 8.910625938732043 0.9240336311306819 1.0053480323900852 0.30421083242317226 0.04786399900200635 0.267924070121862 74.87339022048084 0.025455050998773283 0.012076963522330158 1.0701301869804453e-08 7.970563384886828 0.08131440125940326 KET(ph)PSAPAK ddPTM_PC-9_AZD4547_30min_R2 1 KETPSAPAK 9 1 P49454 P49454 CENPF Centromere protein F 1 KET(0.948)PS(0.052)APAK 68.676 0.03601 11010000.0 80375.0 69520.0 74625.0 82096.0 79402.0 80561.0 68008.0 77175.0 70281.0 77919.0 True False 105932.57809614387 91990.98046230376 73635.42374089123 63170.03557055623 68378.40287828607 75523.50793467741 74060.58025104691 65249.377055074205 73995.91017849479 75191.0795266978 1.4088450220817859 1.2234294419145944 0.9793106337134819 0.8401267273749767 0.9093951477848808 1.0044211149789595 0.9849649814477064 0.867780825409035 0.984104905053549 1.0 16.198273894032567 -5.0896665186901595 2.2989252425735547 0.9367030261850694 1.4117609532130138 0.8899721861457812 0.05401347332544261 0.10824002162404217 0.9950623808990279 0.015373861478994623 0.07896553983541994 8.134549032882794e-06 5.0896665186901595 0.47505792702794436 KET(ph)QSPEQVK ddPTM_PC-9_AZD4547_30min_R2 1 KETQSPEQVK 10 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 KET(0.677)QS(0.323)PEQVK 111.79 0.0052651 189890000.0 28549.0 28860.0 35637.0 31732.0 33950.0 38858.0 29952.0 36799.0 34621.0 36464.0 True False 37626.9881439105 38188.430611940246 35164.430095197866 24416.677654512874 29236.628519657126 36428.20311721166 32617.66997528755 31112.560106895708 36450.99537982766 35187.40645877779 1.0693311025349563 1.0852868811652308 0.9993470287840952 0.6939038739077609 0.8308833034883651 1.0352625209785629 0.9269699946058628 0.884195888189265 1.0359102601815844 1.0 15.102771561527062 -5.527815782663612 24.999423392357667 0.9073823138936055 1.068561025499176 0.31022704510400245 0.09699360488808362 152.35557789297124 771472.9763951347 0.02762601349226251 0.04806131849095989 2.966089266880375e-06 5.527815782663612 0.1611787116055705 KET(ph)SFGSSENITMTSLSK ddPTM_PC-9_AZD4547_30min_R2 1 KETSFGSSENITMTSLSK 18 1 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 KET(0.359)S(0.283)FGS(0.179)S(0.179)ENITMTSLSK 69.398 0.0050989 9206300.0 42483.0 51698.0 93482.0 110990.0 98966.0 88321.0 77934.0 105530.0 94555.0 91507.0 True False 55991.710298705766 68408.36749050896 92242.36759994623 85402.97027840624 85226.27917750782 82798.27390795341 84869.97502183712 89222.76333815338 99552.98426214162 88303.36778256294 0.6340835203089764 0.7746971515169934 1.044607583111469 0.9671541688953631 0.9651532134920142 0.9376570337819368 0.9611182127370254 1.0104117835896627 1.1273973661715777 1.0 16.430180841098718 -5.066069998498043 3.1602250358815898 0.9956759920913255 0.6456080237662962 0.8423447413439042 0.052869931783136086 0.09743387449185206 1.8267635189106257 0.014647404267687522 0.05882984055234837 8.588750790123502e-06 5.066069998498043 -0.3500679683250293 KET(ph)SFGSSENITMTSLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KETSFGSSENITMTSLSK 18 1 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 KET(0.236)S(0.236)FGS(0.166)S(0.197)ENIT(0.12)MT(0.036)S(0.009)LS(0.001)K 50.028999999999996 0.033145 15982000.0 74996.0 71834.0 93675.0 130410.0 135750.0 132630.0 137340.0 128480.0 125500.0 115060.0 True False 87691.34156148131 78965.20478563276 95908.5672644156 123103.55049492462 109150.76198952876 125674.64931822903 124330.16094450651 125107.53613581242 127335.20007732643 135919.4671855414 0.6451713163484912 0.5809705292461061 0.7056278931221266 0.9057094840349691 0.8030546635422642 0.9246258238098642 0.9147340224250988 0.9204534032275906 0.9368429902944165 1.0 17.0523925766104 -5.6532749493509495 2.4925328942654823 0.9111830769333938 0.6112821824582623 0.8711388803387664 0.048507314827456044 0.09231681235458954 1.1568783544476837 0.014043353569595544 0.028293521252637992 2.2219027713506105e-06 5.6532749493509495 -0.2999008944751316 KET(ph)SFGSSENITMTSLSK ddPTM_PC-9_Lapatinib_30min_R1 1 KETSFGSSENITMTSLSK 18 1 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 KET(0.264)S(0.264)FGS(0.2)S(0.264)ENIT(0.006)MT(0.001)S(0.001)LSK 49.593 0.034539999999999994 8880500.0 68266.0 46757.0 55779.0 46870.0 52702.0 55919.0 49730.0 46115.0 67022.0 35324.0 True False 67292.51432154872 46648.737039241496 51193.06593316658 50316.97615373652 49602.17197611858 53527.474723555686 52304.77606924121 48257.671251084284 59473.27658705166 41429.706333728645 1.6242575744922603 1.125973152294926 1.2356608449210613 1.2145144295356154 1.197261008237864 1.292007099745673 1.2624944924279848 1.164808431475578 1.4355225235722568 1.0 15.338377973644631 -11.804421634824724 2.0246971788404617 4.958000007535206e-05 1.2691240716643757 0.26552820524050147 0.1396481877687655 1759130.7042532626 256458.20861477504 8039697.632007879 0.03291961261952847 1.5688389573406168e-12 11.804421634824724 1.2690744916643004 KET(ph)SPESSLIQDEIAVK ddPTM_PC-9_AZD4547_30min_R2 1 KETSPESSLIQDEIAVK 17 1 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 KET(0.45)S(0.45)PES(0.087)S(0.013)LIQDEIAVK 74.12 0.008336 4057900.0 25778.0 25281.0 24971.0 30743.0 26080.0 27498.0 29210.0 28962.0 21966.0 30160.0 True False 33974.86778429104 33452.58885309987 24639.86822423844 23655.67632461521 22459.242173568735 25778.545713034273 31809.633412732015 24486.588380551468 23127.077915522215 29104.107579989548 1.1673564527245759 1.149411256165783 0.8466113642728395 0.8127951100922816 0.7716863371206931 0.8857356523365191 1.0929602746040783 0.8413447590946632 0.7946327799936795 1.0 14.828935160417792 -5.256168823218006 22.859528882886984 0.8764935976810371 1.158384004174121 0.5882875065124034 0.09285996557354755 92.49970071900117 401178.0328134641 0.025267132107603264 0.06250204499829295 5.54410155301058e-06 5.256168823218006 0.28189040649308383 KETES(ph)EAEDNLDDLEK ddPTM_PC-9_AZD4547_30min_R2 4 KETESEAEDNLDDLEK 16 1 A9Z1X7;Q8IYB3;Q8IYB3-2 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 KET(0.343)ES(0.657)EAEDNLDDLEK;KET(0.291)ES(0.709)EAEDNLDDLEK;KET(0.113)ES(0.887)EAEDNLDDLEK;KET(0.032)ES(0.968)EAEDNLDDLEK 106.86 0.00044542 545441000.0 307275.0 299309.0 253860.0 320679.0 320245.0 344971.0 303522.0 309961.0 338256.0 354632.0 True False 404982.05828295666 396054.78094349406 250493.6505308228 246751.41099116128 275784.5095810785 323399.90883595747 330534.8699999735 262063.64964519473 356135.5215966895 342216.4416215803 1.1834091207423107 1.1573224800854183 0.7319743298827714 0.721039029632646 0.805877439068338 0.9450156962171036 0.9658649608819083 0.7657833399336852 1.0406733233188743 1.0 18.384549549506964 -2.396076114249635 10.093264352173474 0.9178852142205015 1.0065214541778968 0.0 0.16176619711801035 0.0 0.0 0.039478534430561665 0.0 0.0040172039934795465 2.396076114249635 0.08863623995739534 KETES(ph)EAEDNLDDLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 KETESEAEDNLDDLEK 16 1 A9Z1X7;Q8IYB3;Q8IYB3-2 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 KET(0.333)ES(0.667)EAEDNLDDLEK;KET(0.172)ES(0.828)EAEDNLDDLEK;KET(0.021)ES(0.979)EAEDNLDDLEK;KET(0.344)ES(0.656)EAEDNLDDLEK;KET(0.276)ES(0.724)EAEDNLDDLEK;KET(0.411)ES(0.589)EAEDNLDDLEK 116.04 7.6133e-05 324433500.0 310097.0 316930.0 228074.0 344709.0 309081.0 289690.0 344871.0 321610.0 274870.0 270982.0 True False 362590.2974050716 348392.7158825982 233512.1491354614 325396.07229165646 248518.79680652314 274498.1464299012 312202.32223018014 313168.0782739625 278889.4537470496 320108.8915076686 1.1327092343399818 1.088356884564239 0.7294772351859753 1.0165168195081553 0.7763570566129356 0.8575149073087376 0.9753003759431685 0.9783173369505113 0.8712330745750887 1.0 18.28820322490938 -5.086746945532835 8.627104443987763 0.9007505029558028 1.1218197719798573 0.4638241320115857 0.09083346560674692 0.2507457264362104 22.801573891498247 0.022269674690955123 0.059510798943578934 8.18941829709981e-06 5.086746945532835 0.22106926902405444 KETES(ph)EAEDNLDDLEK ddPTM_PC-9_Lapatinib_30min_R1 6 KETESEAEDNLDDLEK 16 1 A9Z1X7;Q8IYB3;Q8IYB3-2 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 KET(0.381)ES(0.619)EAEDNLDDLEK;KET(0.015)ES(0.985)EAEDNLDDLEK;KET(0.154)ES(0.846)EAEDNLDDLEK;KET(0.18)ES(0.82)EAEDNLDDLEK;KET(0.135)ES(0.865)EAEDNLDDLEK;KET(0.007)ES(0.993)EAEDNLDDLEK 131.86 3.9804e-06 383119400.0 329210.0 287762.0 245415.7 291184.0 287045.0 262930.0 269033.0 271252.0 261599.0 244166.6 True False 324515.40503027977 287095.70476904465 225238.56847799808 312598.64272134926 270161.5774521834 251685.09681976636 282962.2123514211 283855.35817411065 232134.96586040605 286370.4714784562 1.1332013505264393 1.0025325002499184 0.7865286086067114 1.091588253172486 0.9433988639171123 0.8788793604325952 0.9880984268055322 0.991217274283341 0.8106106913256581 1.0 18.127523214078572 -4.858859062370151 4.023832361360677 0.9391182474983417 1.1362647464709867 0.31837992861328823 0.08725063238787477 0.2534660416788266 6.800404319853707 0.021056400677120408 0.11992720152296554 1.3840154480204802e-05 4.858859062370151 0.19714649897264502 KETQS(ph)PEQVK ddPTM_PC-9_AZD4547_30min_R2 5 KETQSPEQVK 10 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 KET(0.007)QS(0.993)PEQVK;KET(0.475)QS(0.525)PEQVK;KET(0.226)QS(0.774)PEQVK;KET(0.008)QS(0.992)PEQVK;KET(0.01)QS(0.99)PEQVK 72.681 0.01372 979280000.0 213207.0 233802.0 247945.0 252072.0 230019.0 283933.0 272663.0 262540.0 251220.0 242411.0 True False 281002.3910189054 309373.92425269773 244657.08729561503 193960.6948735779 198084.83226695211 266178.6246250258 296929.47878177895 221970.47556902046 264498.9763242051 233924.26467416578 1.201253710940654 1.322538834026586 1.045881613163983 0.829160220483098 0.846790445372845 1.1378837718942378 1.2693402251167634 0.9488988920333006 1.1307034637583535 1.0 17.835681992858376 -5.309174979001517 7.284686874668019 1.0229531873627815 1.2615773992362527 0.34637483779402156 0.12958282958901038 0.27364273337516 36.55538123522514 0.037185884673760376 0.07885270737526479 4.907101272253939e-06 5.309174979001517 0.23862421187347116 KETQS(ph)PEQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KETQSPEQVK 10 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 KET(0.123)QS(0.877)PEQVK;KET(0.03)QS(0.97)PEQVK 127.3 0.00046646 357738000.0 71757.0 100480.0 74029.0 87680.0 85210.0 62835.0 84010.0 72262.0 70014.0 59175.0 True False 83904.04283464738 110454.99035081423 75794.13211654595 82767.57386239537 68513.71218510314 59539.82198530435 76051.96462027075 70365.19906791786 71037.8222965252 69902.95907095775 1.200293148527193 1.5801189508829312 1.0842764472904236 1.1840353393105847 0.9801260647000023 0.8517496652018137 1.0879648820455685 1.006612595562527 1.0162348381334683 1.0 16.093065907348137 -5.632915781358808 1.6822855123986253 0.9966965049063435 1.3841456762050197 0.575178228556509 0.121894909997882 0.24997661182170522 1.4055969741798988 0.03600937809909021 0.09056801199868102 2.328542766267045e-06 5.632915781358808 0.3874491712986762 KETQS(ph)PEQVK ddPTM_PC-9_Lapatinib_30min_R1 4 KETQSPEQVK 10 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 KET(0.114)QS(0.886)PEQVK;KET(0.133)QS(0.867)PEQVK;KET(0.003)QS(0.997)PEQVK;KET(0.004)QS(0.996)PEQVK 122.1 0.00083346 788140000.0 239621.0 292922.0 277024.0 254903.0 305889.0 273578.0 297752.0 303308.0 270102.0 252193.0 True False 236203.96059889 292243.75710607384 254248.1560635637 273649.41695148067 287897.2104209129 261877.70668146614 313168.14164827496 317400.79696029186 239680.26845984647 295784.22402395017 0.7985684881549469 0.9880302374828833 0.8595730786608038 0.9251656941964653 0.9733352458906035 0.8853673908594308 1.0587722948432747 1.0730822375928724 0.8103213389786439 1.0 18.17418558120319 -2.3001303321057978 0.36739635359931944 0.9805390920335175 1.4570161067685576e-16 0.1974838103775306 0.08271373236586531 63.53555330287698 1.5166563944120666 0.06623101460660055 39.95446109974946 0.005010368495219006 2.3001303321057978 -0.9805390920335174 KETQS(ph)PEQVKSEK ddPTM_PC-9_Lapatinib_30min_R1 1 KETQSPEQVKSEK 13 2 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 KET(0.224)QS(0.776)PEQVKSEK 80.545 0.035526 37660000.0 171810.0 81141.0 94510.0 91874.0 64076.0 78500.0 50905.0 48190.0 70287.0 49441.0 True False 169359.95789390468 80953.12299978822 86739.75261915 98630.72044267949 60307.17565826297 75142.73799243763 53540.61181992207 50429.08332624425 62370.537905077406 57986.81097400853 2.9206634241330676 1.3960609600702805 1.4958531287059296 1.700916446101663 1.0400153870385198 1.2958591226221927 0.9233239579931481 0.8696647130473878 1.075598689726769 1.0 15.823437177959558 -1.5228787452803376 0.6676256925254526 1.0643142217169395 169.57367695449244 0.8199031815152189 0.24446400859449524 101.97459888038607 0.6152044366883117 0.10318688467214364 25494.221534886838 0.029999999999999995 1.5228787452803376 168.50936273277551 up KETSFGSS(ph)ENITMTSLSK ddPTM_PC-9_AZD4547_30min_R2 2 KETSFGSSENITMTSLSK 18 1 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 KET(0.246)S(0.246)FGS(0.193)S(0.314)ENIT(0.001)MTSLSK;KETS(0.002)FGS(0.435)S(0.562)ENIT(0.001)MTSLSK 83.039 0.0011004 14066100.0 90613.0 108190.0 170281.0 236317.0 203501.0 191487.0 168842.0 197054.0 157933.0 181122.0 True False 119426.04913251448 143160.30172923845 168022.96268037098 181837.7667112541 175248.39883295295 179513.28761916462 183868.61090970563 166603.83215044547 166281.01595339034 174780.97390924656 0.6832897566672524 0.8190840142793411 0.9613343999765981 1.040375062823896 1.0026743467166461 1.02707567994429 1.0519944293546375 0.953214920503607 0.9513679448870118 1.0 17.415188620712854 -5.044300235549628 1.83981197966142 1.0054496687442467 0.6578812215388138 0.9144987021750195 0.03178906873205413 0.1425432945438813 0.7267220718894055 0.009733493227108325 0.07188064372939393 9.030249805514502e-06 5.044300235549628 -0.3475684472054329 KETTSGTSTEPVKNS(ph)SPAPPQPAPGK ddPTM_PC-9_AZD4547_30min_R2 1 KETTSGTSTEPVKNSSPAPPQPAPGK 26 2 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 KETTSGTSTEPVKNS(0.5)S(0.5)PAPPQPAPGK 79.237 1.3887000000000001e-05 19953000.0 59323.0 52021.0 77350.0 97854.0 93032.0 74881.0 70398.0 90872.0 68583.0 76557.0 True False 78186.48000494589 68835.77092389959 76324.28846040776 75295.27212922937 80116.11264921166 70198.67923258865 76663.28562100348 76829.82043082207 72208.15736503049 73876.76273213717 1.0583365744981938 0.9317648524135358 1.0331298454040934 1.0192010226847033 1.0844561900972456 0.9502132556500271 1.0377185299655007 1.0399727544829234 0.9774136642511433 1.0 16.172833028590183 -4.423936700957232 23.07356522187629 1.0110706816211372 10.125966821846825 0.104582192280951 0.04328045204940884 2038.2211147780108 488159.0304481673 0.010090192684416839 26523.286500764876 3.767587081035996e-05 4.423936700957232 9.114896140225689 KETTSGTSTEPVKNS(ph)SPAPPQPAPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KETTSGTSTEPVKNSSPAPPQPAPGK 26 2 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 KET(0.029)T(0.029)S(0.029)GT(0.074)S(0.074)T(0.074)EPVKNS(0.345)S(0.345)PAPPQPAPGK 43.888000000000005 0.016155000000000003 5064700.0 10440.0 8283.8 10251.0 15516.0 18497.0 13468.0 13839.0 12926.0 11413.0 10675.0 True False 12207.285800600923 9106.160918273024 10495.422717133997 14646.68882355072 14872.645631825517 12761.714370941017 12528.06973431651 12586.70619622908 11579.893533725304 12610.2929967465 0.9680414090101194 0.7221212798641907 0.8322901553391228 1.1614867971211784 1.1794052394867203 1.0120077601871411 0.9934796707379278 0.9981295596760912 0.9182890149113075 1.0 13.622314176234013 -5.737368641317298 24.336484963168015 1.0404756569406892 0.8289477145436129 0.48410042768869077 0.09278757579937058 145.34742269616737 146950.37462617893 0.026639008266921015 0.04610520679090357 1.830759762494033e-06 5.737368641317298 -0.21152794239707629 KETTSGTSTEPVKNS(ph)SPAPPQPAPGK ddPTM_PC-9_Lapatinib_30min_R1 2 KETTSGTSTEPVKNSSPAPPQPAPGK 26 2 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 KETTSGTSTEPVKNS(0.5)S(0.5)PAPPQPAPGK;KET(0.001)T(0.001)S(0.001)GT(0.001)S(0.001)T(0.004)EPVKNS(0.495)S(0.495)PAPPQPAPGK 71.428 6.6956e-05 30832000.0 154570.0 112914.0 128642.0 123861.0 122198.0 121987.0 106095.0 95407.0 128255.0 81425.0 True False 152365.80345533384 112652.55457041571 118065.5513324802 132970.1511281834 115010.55389051154 116769.90037558584 111588.07997317796 99839.95752037733 113809.5713149758 95499.20275800752 1.5954667584128925 1.1796177488085877 1.2362988163540507 1.3923692270513115 1.2043090472906384 1.2227316773677965 1.1684713248961798 1.0454533088969251 1.1917332085312404 1.0 16.543201068908623 -1.5228787452808534 0.15174560514135832 0.9711492586771066 2.6760867643585997 0.592563597219345 0.1019343980128264 51.04071161760382 0.5081539011340093 0.3501070356536539 19.19857600594755 0.029999999999964364 1.5228787452808534 1.7049375056814933 KEVLAS(ph)PDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KEVLASPDR 9 1 Q9C0C2;E9PKK0 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 KEVLAS(1)PDR 54.608000000000004 0.043269999999999996 13160000.0 51382.0 68740.0 74503.0 59356.0 69864.0 57233.0 67760.0 51509.0 58218.0 49779.0 True False 60079.95775924109 75564.05291316622 76279.43407420086 56030.4757547484 56174.65072292032 54231.60072706171 61341.28226008279 50156.94332829675 59069.32811236477 58803.538649652844 1.0217065016646882 1.2850256064243222 1.2971912205601794 0.9528419044400346 0.9552937121285294 0.922250632741162 1.0431563077444987 0.8529579083178672 1.0045199569416303 1.0 15.843615354997036 -5.773352929086922 24.996473802577437 0.9569466138635818 1.2096795514842544 0.6248168373247663 0.08500305140105367 125.04778053343962 262369.5653664228 0.023293983153578546 0.03485675326720475 1.6851830060780833e-06 5.773352929086922 0.2527329376206726 KEVLAS(ph)PDR ddPTM_PC-9_Lapatinib_30min_R1 2 KEVLASPDR 9 1 Q9C0C2;E9PKK0 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 KEVLAS(1)PDR;KEVLAS(1)PDR 87.641 0.015768 53462000.0 146950.0 197355.0 181029.0 185086.0 230862.0 188008.0 215800.0 234931.0 209151.0 184360.0 True False 144854.46605267047 196898.03662295488 166145.4944121482 198697.8418687959 217283.15105215544 179967.33610805369 226973.0680824905 245846.7519177809 185594.21192233075 216226.38035574128 0.6699204131075595 0.9106106123545753 0.768386790449904 0.9189343203261925 1.0048873347214875 0.8323098033272662 1.04970109433025 1.136987778796035 0.8583328806456748 1.0 17.722183021962003 -3.4303401983844664 0.3604906410338342 1.0165208504642125 1.3111965070141902e-13 0.47244701102189923 0.09591130618554844 14.669670230128926 0.7062259930998336 0.08153376992683418 7.8749986708321655 0.00037124430623774904 3.4303401983844664 -1.0165208504640812 KEVS(ph)PEVVR ddPTM_PC-9_AZD4547_30min_R2 1 KEVSPEVVR 9 1 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 KEVS(1)PEVVR 64.64 0.024427 37148000.0 181720.0 150610.0 208280.0 285260.0 245000.0 201880.0 207720.0 209840.0 183680.0 211060.0 True False 239503.1799891917 199291.73716092596 205518.07111226543 219497.71422306643 210985.97900783533 189256.41168620833 226206.67759303964 177414.04964349585 193388.94980984784 203670.85364166377 1.175932519095594 0.9784990517669142 1.009069621094885 1.0777080289025953 1.035916407455343 0.9292267808686262 1.1106482520617562 0.871082172393877 0.9495170582929564 1.0 17.635880012348736 KEVS(ph)PEVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KEVSPEVVR 9 1 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 KEVS(1)PEVVR 61.343999999999994 0.030366000000000004 23050000.0 70434.0 63065.0 69957.0 75562.0 76129.0 72089.0 64618.0 76467.0 67355.0 50918.0 True False 82357.08506508885 69325.67641793474 71625.04019339995 71328.50611530941 61212.06894659917 68308.52593456842 58496.9152461929 74459.82227348357 68339.93945185894 60149.030333333794 1.3692171695650368 1.1525651541470547 1.1907929320966344 1.1858629427610257 1.0176734123122888 1.1356546490611128 0.9725329722194155 1.2379222384939916 1.1361769104694253 1.0 15.876253859352019 -1.5228788053413795 0.7073017142500471 1.0989399648957692 34.5973485124173 0.489599211092686 0.08133537988430127 266.6537709778923 1.3742383484836904 0.031408935847523266 14143.426828647527 0.02999999585113049 1.5228788053413795 33.49840854752153 KEVS(ph)PEVVR ddPTM_PC-9_Lapatinib_30min_R1 1 KEVSPEVVR 9 1 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 KEVS(1)PEVVR 61.48 0.030105 5729700.0 32578.0 36020.0 38026.0 28030.0 39893.0 30371.0 29772.0 35110.0 37986.0 33271.0 True False 32113.43174592649 35936.59790306221 34899.64906460484 30091.419705338914 37546.57217265569 29072.103128258917 31313.44848448522 36741.338775356584 33707.61666968675 39021.84801917918 0.8229602998336415 0.9209353151444654 0.8943617700384593 0.771142865672303 0.962193593553068 0.7450211767000379 0.8024593932377243 0.941558143461024 0.8638139498959533 1.0 15.251994483097933 -8.885816151281922 1.0532331201848761 0.9989742012612364 0.8530702260821034 0.2824553862246436 0.06874071006558535 1.6408311105920483 3.0583081644937935 0.06532209667351453 0.02066677820606561 1.3007200918487468e-09 8.885816151281922 -0.145903975179133 KEVVEEAENGR ddPTM_PC-9_AZD4547_30min_R2 1 KEVVEEAENGR 11 1 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 0 113.67 0.0009708999999999999 8532600.0 32533.0 34820.0 37910.0 44255.0 43705.0 50930.0 43830.0 52994.0 46400.0 39294.0 False True 42877.817271562584 46074.88405778797 37407.28863004605 34052.6934829342 37637.31515321402 47745.33904883394 47730.78509003918 44804.994980973155 48852.609272522546 37918.329020162775 1.130793955840265 1.2151085042088223 0.986522602569196 0.8980536422063047 0.992588970183804 1.2591625285873154 1.2587787047435215 1.1816183924441515 1.2883639795030406 1.0 15.210607768694869 -6.762200584077621 24.999999143453635 1.212760505536127 1.0427159793830787 0.322756367462932 0.1096805015664283 24.317793873221262 798647.0776597426 0.03957305462491765 0.03698048744016638 1.7290176074033533e-07 6.762200584077621 -0.17004452615304833 KEVVEEAENGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KEVVEEAENGR 11 1 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 0 85.92399999999999 0.0070861000000000006 6273100.0 27794.0 27480.0 38783.0 35125.0 32798.0 27693.0 31914.0 25906.0 22392.0 23820.0 False True 32498.9752434772 30208.032791006888 39707.73380534653 33157.06012678648 26371.467342412998 26240.730329259703 28890.874882648823 25225.99494967591 22719.440638497937 28138.37744098376 1.1549697672383268 1.0735527609708106 1.4111593281676544 1.17835721680572 0.9372063971251858 0.9325601799284944 1.026742744610748 0.8964978525355217 0.8074182914828237 1.0 14.780251519590275 -6.23934616603629 4.972123946564513 0.9318549943194192 1.2127916022088152 0.65593650178975 0.09634467867714777 0.12273584434741783 8.727169930994249 0.030286165197277146 0.03797345762787678 5.763069194215356e-07 6.23934616603629 0.280936607889396 KEVVEEAENGR ddPTM_PC-9_Lapatinib_30min_R1 1 KEVVEEAENGR 11 1 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 0 80.737 0.010020000000000001 15150000.0 71662.0 87394.0 98516.0 91308.0 102820.0 96585.0 108070.0 89992.0 100690.0 80802.0 False True 70640.08673879877 87191.6445624712 90416.39476275753 98023.09491455904 96772.32975189772 92454.28470063164 113665.33580942884 94173.35685194813 89349.2318872943 94768.51803810257 0.745396131554967 0.9200486233984897 0.9540762759042488 1.0343423844102737 1.0211442761296479 0.9755801463884824 1.1993997390961482 0.9937198428499732 0.942815543990786 1.0 16.532120257095848 -4.033826235067536 0.8621247430959633 1.0310431088244878 1.4598781442567642e-07 0.6209596680800156 0.06575196783575524 4.752672266501165 1.0830117308538023 0.023310218838131717 6.3093635387082685 9.250682276033558e-05 4.033826235067536 -1.0310429628366733 KEYEEDDILAS(ph)DDPSSIEQYENTR ddPTM_PC-9_AZD4547_30min_R2 3 KEYEEDDILASDDPSSIEQYENTR 24 1 Q96RS0 Q96RS0 TGS1 Trimethylguanosine synthase 1 KEYEEDDILAS(0.984)DDPS(0.012)S(0.003)IEQYENT(0.002)R;KEYEEDDILAS(0.996)DDPS(0.002)S(0.002)IEQYENTR;KEYEEDDILAS(0.998)DDPS(0.001)SIEQYENTR 96.38 7.5517e-05 2440600.0 20452.4 18334.0 23794.9 33216.8 28786.4 28547.1 20973.0 29556.6 23219.399999999998 25473.199999999997 True False 26955.837763652507 24260.106959089135 23479.364078688537 25559.17995444422 24789.905249433235 26762.045324189436 22839.55636991539 24989.30661310018 24446.73008065539 24581.391021438645 1.0965952960165268 0.9869297851342382 0.9551682432540545 1.0397776078722638 1.0084826049027387 1.0887115908472769 0.9291401105004955 1.0165944877287771 0.9945218339895489 1.0 14.585278937365349 -7.268947781341257 24.99991934891017 0.9864469891569325 1.0235160741335187 0.17926108979611977 0.04531367710533293 1279.2557854516951 4259378.098724044 0.018839468547945687 0.012957292767909169 5.3833450683844944e-08 7.268947781341257 0.03706908497658623 KEYEEDDILAS(ph)DDPSSIEQYENTR ddPTM_PC-9_Lapatinib_30min_R1 2 KEYEEDDILASDDPSSIEQYENTR 24 1 Q96RS0 Q96RS0 TGS1 Trimethylguanosine synthase 1 KEYEEDDILAS(1)DDPSSIEQYENTR;KEYEEDDILAS(0.997)DDPS(0.002)S(0.001)IEQYENTR 111.38 3.4851999999999997e-06 2620800.0 26660.0 22373.0 23678.0 22792.5 22015.4 20617.8 18790.4 16573.3 23751.0 19252.300000000003 True False 26279.823511154787 22321.196693093014 21731.286239723177 24468.736483551096 20720.49745594173 19736.024756439256 19763.27496986667 17343.356021806256 21075.912270882174 22580.034402922774 1.1638522352186103 0.9885368770830457 0.9624115646568839 1.0836447831268072 0.9176468505849422 0.874047594625658 0.8752544224338515 0.7680836845652157 0.9333870752718647 1.0 14.462760063751075 -6.413785869682597 4.200877516067083 0.8762440942506685 1.0385265425842398 0.49946149017107644 0.07522614115563968 0.1926904593968888 5.767121586142547 0.023705713043142704 0.02679499763891354 3.856684658960501e-07 6.413785869682597 0.1622824483335713 KFAETQPK ddPTM_PC-9_AZD4547_30min_R2 1 KFAETQPK 8 1 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 0 86.13600000000001 0.0080378 6648700.0 63149.0 60119.0 74563.0 75226.0 80758.0 60165.0 50471.0 79455.0 60408.0 67247.0 False True 83229.06841920227 79551.29105887859 73574.24590140136 57883.8079301143 69546.14568455011 56402.87303893765 54962.82122471748 67177.05544426212 63601.04355462379 64892.70299839374 1.2825643650760303 1.2258896206072305 1.1337830372580182 0.8919925547183182 1.0717097989626285 0.8691712693849996 0.8469799944390967 1.035201992524875 0.9800954593646389 1.0 15.985768639901847 -5.525121755863514 2.704523064364165 0.9541527618847289 1.2554294530090488 0.7475892544364726 0.07040092340557161 0.13396563456063634 1.9575328650651387 0.020300378473153333 0.04518201110093787 2.9845457745506085e-06 5.525121755863514 0.30127669112432 KFAETQPK ddPTM_PC-9_Lapatinib_30min_R1 2 KFAETQPK 8 1 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 0 ; 72.643 0.020325 26600000.0 184242.0 147089.0 157349.0 152998.0 169020.0 175288.0 173259.0 161904.0 165789.0 146190.0 False True 181614.67529415534 146748.42445762138 144412.37260470464 164249.98330636608 159078.57590610543 167791.3408562857 182229.50325720196 169426.65089961048 147116.0969844336 171458.74671406922 1.0592324904661907 0.8558818215459392 0.8422572506349408 0.9579562807622481 0.9277950466498545 0.9786105641848682 1.0628183557243331 0.9881481939335091 0.8580262004934032 1.0 17.387501977538825 -6.7374420269184885 4.378979502980689 0.982527867882059 0.9205375285149129 0.09505043815699177 0.07295918610642452 0.4420805653445262 19.506223406993364 0.025999272256069156 0.024809252108603335 1.830450433085252e-07 6.7374420269184885 -0.06199033936714615 KFDQLLAEEK ddPTM_PC-9_AZD4547_30min_R2 2 KFDQLLAEEK 10 1 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580;Q7Z406;Q7Z406-6;Q7Z406-2;A0A0C4DFM8;A1L2Z2;P35749-4;P35749-3;P35749;P35749-2 P35579;Q7Z406;P35749-4 MYH9;MYH10;MYH14;MYH11 Myosin-9;Myosin-10;Myosin-14;Myosin-11 0 ; 146.36 8.9916e-05 18447100.0 152584.0 144582.0 162844.0 221380.0 197951.0 191144.0 158882.0 201725.0 157152.0 178526.0 False True 201102.5380556387 191315.30404489062 160684.58215962045 170344.2612869046 170468.92053297942 179191.73546338716 173022.19020478186 170553.03642934668 165458.73388783343 172275.8590790855 1.1673286038487838 1.1105171964753624 0.9327167661132143 0.988787762821173 0.9895113653429726 1.0401441990843698 1.0043321863532473 0.9899996281606239 0.9604290164176597 1.0 17.394361026104228 -5.09089265115255 4.649667476367145 0.9907562921758006 1.1560210215997277 0.8367592553843469 0.02707151256247639 0.07782492387171379 2.7963417649544025 0.007331797392655598 0.022009456426303538 8.11161535867295e-06 5.09089265115255 0.16526472942392711 KFDQLLAEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KFDQLLAEEK 10 1 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580;Q7Z406;Q7Z406-6;Q7Z406-2;A0A0C4DFM8;A1L2Z2;P35749-4;P35749-3;P35749;P35749-2 P35579;Q7Z406;P35749-4 MYH9;MYH10;MYH14;MYH11 Myosin-9;Myosin-10;Myosin-14;Myosin-11 0 ; 142.97 8.093e-05 16169000.0 173795.0 204416.0 188976.0 225191.0 224032.0 210505.0 208876.0 197641.0 181648.0 165448.0 False True 203215.060892283 224709.0695417193 193481.90453547085 212574.27834907197 180134.5378271682 199465.74722712635 189089.7531487165 192453.133167949 184304.25835574625 195442.41271435295 1.039769505860993 1.1497456791537912 0.9899688703610743 1.0876568468265788 0.9216757781763684 1.020585780010062 0.9674960031581215 0.984705062197667 0.9430105563888758 1.0 17.57638405317072 -5.900117536951481 1.3228431372529559 0.9747228602744532 1.0856094202247233 0.4208634048170059 0.04919683591857564 0.39722087665808464 1.4081021703181722 0.016186714367942705 0.03355059799000873 1.2585847437917695e-06 5.900117536951481 0.11088655995027008 KFDQLLAEEK ddPTM_PC-9_Lapatinib_30min_R1 2 KFDQLLAEEK 10 1 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580;Q7Z406;Q7Z406-6;Q7Z406-2;A0A0C4DFM8;A1L2Z2;P35749-4;P35749-3;P35749;P35749-2 P35579;Q7Z406;P35749-4 MYH9;MYH10;MYH14;MYH11 Myosin-9;Myosin-10;Myosin-14;Myosin-11 0 ; 128.36 0.00017852 17067800.0 159739.0 150587.0 158396.0 129862.0 154011.0 132842.0 145776.0 132472.0 134221.0 118040.0 False True 157461.09256745505 150238.3250535376 145373.29230624155 139412.48468693276 144952.37577727597 127160.65732982685 153323.56799255405 138627.1327328124 119103.61757021079 138443.05672158694 1.1373708172603696 1.0851994214175096 1.0500583831993215 1.0070023588636545 1.0470180246654006 0.9185051265196396 1.107484706155342 1.0013296153348856 0.8603076267647837 1.0 17.078933175057365 -1.5228788144032819 0.3287205335466401 0.970840514453824 2.7129637375458606 0.4145106615175347 0.061220482342939635 60.11625532481732 0.8561676377937772 0.055948724609216155 63.541891205105344 0.029999995225156544 1.5228788144032819 1.7421232230920367 KFEEFQTDMAAHEER ddPTM_PC-9_AZD4547_30min_R2 1 KFEEFQTDMAAHEER 15 1 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 70.47 0.008381200000000002 5204100.0 14284.0 16388.0 19770.0 18684.0 19101.0 18962.0 21228.0 21928.0 16693.0 18614.0 False True 18826.014874342996 21685.100515193233 19507.836882511485 14376.69246492244 16449.155857259826 17776.303142430574 23117.250875914917 18539.531455311528 17575.35790056506 17962.329525660643 1.0480831479819201 1.2072543532961195 1.086041588015795 0.800380175877754 0.9157584952308593 0.9896435268619075 1.2869851231094525 1.032134024087817 0.9784564900369541 1.0 14.132686844170763 -5.532653681672767 24.991414826639325 1.0046544838089841 1.1324136125843969 0.1628009862472558 0.11989257539331317 373.1240887077426 953957.1751122475 0.03566221775262031 0.06186795718783659 2.9332313519937992e-06 5.532653681672767 0.12775912877541273 KFELLPTPPLS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 1 KFELLPTPPLSPSR 14 1 H0YBT0;A0A087WUS5;P01106;P01106-2;H0YBG3;A0A0B4J1R1;P04198 H0YBT0 MYC;MYCN Myc proto-oncogene protein;N-myc proto-oncogene protein 1 KFELLPT(0.122)PPLS(0.439)PS(0.439)R 65.28699999999999 0.018006 3180700.0 21159.0 20022.0 23100.0 23201.0 32785.0 30046.0 26407.0 38642.0 40098.0 37954.0 True False 20857.268779914633 19975.640289148007 21200.807168578634 24907.27893626714 30856.650757789976 28761.002620646894 27774.225249556654 40437.448389556535 35581.74098934078 44514.29832947391 0.4685521183674274 0.4487466058949803 0.47626960244684136 0.5595343489841212 0.6931851543385802 0.6461070644710936 0.6239394147917349 0.90841482191312 0.7993328508961651 1.0 15.441981194633309 -7.179317322273497 0.3221070042285281 1.0268092988997917 0.35826899048218014 0.8838150345420573 0.061391629945268006 0.5531143454138758 0.14544312958840697 0.08607856889723037 0.1333666023622897 6.617328242980727e-08 7.179317322273497 -0.6685403084176116 down KFELLPTPPLS(ph)PSRR ddPTM_PC-9_AZD4547_30min_R2 2 KFELLPTPPLSPSRR 15 2 H0YBT0;A0A087WUS5;P01106;P01106-2;H0YBG3;A0A0B4J1R1 H0YBT0 MYC Myc proto-oncogene protein 1 KFELLPTPPLS(0.5)PS(0.5)RR;KFELLPTPPLS(0.741)PS(0.259)RR 96.455 0.004485 11759300.0 42601.0 30737.0 50626.0 63351.0 63436.0 51695.0 42824.0 54090.0 44972.0 54109.0 True False 56147.23184415326 40672.13415520471 49954.66616155924 48746.405713193184 54629.006385065426 48462.50347790045 46635.253038919414 45731.633364547655 47349.12810784232 52214.660379497785 1.075315465734593 0.7789408924543101 0.9567172475792654 0.9335769946391067 1.0462388529968423 0.9281397815416869 0.8931448122035638 0.8758389508266206 0.9068167400440293 1.0 15.67216731062239 -9.732591141792124 9.959993005828247 1.000001535160357 0.9293172572441565 0.059166330883481555 0.07940033193846459 0.0 0.0 0.0745950826664211 0.018091964999137376 1.8510103971936617e-10 9.732591141792124 -0.07068427791620058 KFELLPTPPLS(ph)PSRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KFELLPTPPLSPSRR 15 2 H0YBT0;A0A087WUS5;P01106;P01106-2;H0YBG3;A0A0B4J1R1 H0YBT0 MYC Myc proto-oncogene protein 1 KFELLPTPPLS(0.5)PS(0.5)RR 57.745 0.019633 3548400.0 20736.0 19924.0 21721.0 27558.0 32706.0 40813.0 35087.0 36501.0 33497.0 29159.0 True False 24246.195245331484 21901.923046871216 22238.91101735122 26014.014604241467 26297.494081985475 38672.694432819735 31763.305352118157 35542.88742600632 33986.83025490197 34445.295877483 0.7039043976156205 0.6358465644996412 0.6456298443901267 0.7552269168123742 0.7634567627324761 1.1227278920864256 0.9221376836214646 1.0318647734200714 0.9866900367408159 1.0 15.072019350066162 -6.617913803944449 4.923171671294 1.0080647156344853 0.6874273014699356 0.8857549496568383 0.056440423852091415 0.06783038167363951 2.7581491805516385 0.019357686786788685 0.01934607427170425 2.4103837791288365e-07 6.617913803944449 -0.3206374141645497 KFELLPTPPLSPS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 KFELLPTPPLSPSR 14 1 H0YBT0;A0A087WUS5;P01106;P01106-2;H0YBG3;A0A0B4J1R1;P04198 H0YBT0 MYC;MYCN Myc proto-oncogene protein;N-myc proto-oncogene protein 1 KFELLPTPPLS(0.383)PS(0.617)R;KFELLPTPPLS(0.251)PS(0.749)R 84.436 0.0033407 11761100.0 67541.0 51856.0 103269.0 118546.0 106389.0 96028.0 88941.0 121072.0 86331.0 105050.0 True False 89017.6330599272 68617.43790065058 101899.58558523419 91217.05121744247 91618.7237578146 90023.35397960764 96856.57669845263 102363.1043577834 90894.28041177028 101372.23147473126 0.878126403699778 0.6768859371291893 1.0052021554900306 0.8998228596771084 0.9037852124292254 0.8880474728628961 0.9554547166360421 1.0097745987104874 0.8966388436899232 1.0 16.629302988709533 -1.959066463410668 0.24667743435195466 0.9860137281954638 4.807183387100708e-07 0.29823219990764005 0.07738173026816109 46.96176242417966 0.7688483498147785 0.09995421071862758 18.318001633917163 0.010988376630210198 1.959066463410668 -0.9860132474771252 KFGDPVVQSDMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KFGDPVVQSDMK 12 1 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 75.102 0.018658 6682100.0 45698.0 40996.0 55201.0 64012.0 64059.0 47788.0 58582.0 54582.0 56265.0 52786.0 False True 53433.76882335834 45065.81194687474 56517.20119095828 60425.6151697041 51507.09880137915 45281.91315403395 53032.68886304857 53149.28033440939 57087.76918207783 62355.683946253936 0.8569189758132452 0.7227217968728912 0.9063680744753276 0.969047428327249 0.826020910070917 0.7261874185048418 0.8504868442908732 0.8523566252632271 0.9155182907027903 1.0 15.928233452472444 -8.511654393318361 1.813893832281408 0.999317592589289 0.8359793333998905 0.35353731887397655 0.06950181248996617 0.43719884825839134 3.2349754106512556 0.07120220148349704 0.020268822313767986 3.078545712386033e-09 8.511654393318361 -0.16333825918939848 KFGDPVVQSDMK ddPTM_PC-9_Lapatinib_30min_R1 3 KFGDPVVQSDMK 12 1 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 ;; 92.19 0.0048018 21046600.0 242287.0 222845.0 227392.0 213290.0 233781.0 221607.0 219804.0 204612.0 221651.0 205572.0 False True 238831.94295000544 222329.01609405648 208696.70751850324 228976.05811458192 220030.46121113028 212129.38520114808 231184.375610768 214119.02049282962 196686.3302914953 241104.8462925285 0.9905729669997367 0.9221258697733035 0.8655848720074876 0.9496949631479786 0.9125924451314056 0.8798221539843086 0.9588541216225734 0.8880743120071612 0.8157709532427194 1.0 17.879301124348338 -4.789537231828899 4.070315831033666 0.9064340715598178 0.9970366762467693 0.19451535160644517 0.04937080550456792 0.3368560860317556 10.609708225223399 0.011879656049819585 0.08756360964862435 1.6235391593901172e-05 4.789537231828899 0.09060260468695147 KFGYVDFESAEDLEK ddPTM_PC-9_AZD4547_30min_R2 1 KFGYVDFESAEDLEK 15 1 P19338 P19338 NCL Nucleolin 0 122.63 2.9795e-05 3946900.0 23875.0 20872.0 25358.0 35004.0 31848.0 25034.0 21636.0 33182.0 22617.0 27944.0 False True 31466.753369149992 27618.465825794075 25021.73635137714 26934.36860640894 27426.454936496026 23468.620022550742 23561.562085514208 28054.484346504363 23812.48844647936 26965.689065491617 1.1669182008561558 1.0242076795707709 0.9279101413135339 0.9988385070002622 1.0170871165163013 0.8703141227191511 0.873760801301617 1.0403770613229422 0.8830661952915769 1.0 14.71883727965663 -4.804075044410906 2.2784890948619516 0.9509882568317418 1.2154191240061216 0.5525752003552367 0.059111501373059545 0.4363443187567271 2.8194763693143474 0.01571238266306158 0.23119305143097924 1.570091475142629e-05 4.804075044410906 0.2644308671743798 KFGYVDFESAEDLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KFGYVDFESAEDLEK 15 1 P19338 P19338 NCL Nucleolin 0 ; 161.14 0.00018765 6100500.0 37065.0 38888.0 39130.0 51604.0 46629.0 38523.0 46750.0 50151.0 42331.0 37217.0 False True 43339.372432880555 42748.54363816139 40063.00760135137 48712.79518242532 37492.38217907724 36502.7860641343 42321.50155931041 48834.589389376815 42950.01079261591 43964.147490390074 0.9857889873186763 0.9723501097685473 0.9112654262227776 1.1080118224303843 0.8527944773015906 0.8302853153723333 0.9626366931955471 1.1107821299173684 0.9769326427176636 1.0 15.42403987324265 -7.545482502129035 24.16962979739151 1.033656415166569 0.9424513404518404 0.19195790722213812 0.07878655297261025 264.21244229288016 282510.6968681337 0.038212162488739945 0.022063986324622673 2.8478525388003695e-08 7.545482502129035 -0.0912050747147286 KFGYVDFESAEDLEK ddPTM_PC-9_Lapatinib_30min_R1 1 KFGYVDFESAEDLEK 15 1 P19338 P19338 NCL Nucleolin 0 142.19 5.5747e-05 2809200.0 33897.0 28147.0 30772.0 27568.0 24707.0 25250.0 26521.0 26339.0 26506.0 24127.0 False True 33413.622564051526 28081.827350846517 28242.04494335507 29595.442684152087 23253.782835830938 24170.11636062487 27894.12761175037 27562.80609524688 23520.615159446024 28297.319802793303 1.1808052068858188 0.992384704507403 0.9980466397586963 1.045874411089302 0.8217662661301052 0.8541486094467142 0.9857515766916154 0.9740429937299604 0.8311958631899916 1.0 14.788377793372273 -1.52287874528221 0.6615120044211819 0.9205605297649132 24.977362032285995 0.5214472859282722 0.0716525796960933 194.2120575920911 1.1996204590805863 0.030451939803192 6859.42255726038 0.029999999999870665 1.52287874528221 24.056801502521083 KFPVFK ddPTM_PC-9_Lapatinib_30min_R1 1 KFPVFK 6 1 P04080;A0A1W2PS52 P04080 CSTB Cystatin-B 0 72.021 0.043318 2716400.0 19881.0 26167.0 27451.0 22075.0 24892.0 23272.0 25105.0 22821.0 26555.0 22599.0 False True 19597.493294271124 26106.41191919568 25194.084743924333 23698.46914004126 23427.90149955494 22276.710809681663 26404.814060291577 23881.346972156436 23564.096263453153 26505.207038725344 0.7393827660217206 0.9849540839674633 0.9505334067798301 0.8941061696072281 0.8838980757752876 0.8404654518311948 0.9962123299664444 0.9010058641407582 0.8890364911703919 1.0 14.693988189451806 -14.52287874161133 0.1676454871224543 1.3633439457716818 0.8798352231199652 0.17918962217132028 0.06908793039163287 261.2062828309774 2.4420176210286 31.73377662508539 0.2562093056607652 3.000000025344612e-15 14.52287874161133 -0.4835087226517166 KFPVFNPATEEELCQVEEGDKEDVDK ddPTM_PC-9_Lapatinib_30min_R1 2 KFPVFNPATEEELCQVEEGDKEDVDK 26 2 P00352;Q5SYQ7;Q5SYQ9;Q5SYQ8 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ; 107.57 2.843e-09 20843000.0 77378.0 66289.0 64667.0 60202.0 59780.0 33259.0 74808.0 57473.0 42768.0 66714.0 False True 76274.57553061275 66135.511893284 59350.32888183874 64629.455907984804 56263.85793200203 31836.590100515736 78681.19220164481 60143.405395501846 37951.017472994354 78245.42600918289 0.9748119400827489 0.8452316674143013 0.7585149945362094 0.8259838204523275 0.7190689705670322 0.4068811651275231 1.0055692225691348 0.7686507501210794 0.4850253798674496 1.0 16.255718798473424 -4.5389299920796 0.9696841785313118 0.7276567184501658 1.2084255528415642 0.13698333145967545 0.17968705956010217 5.883387989937114 3.2291302021756922 0.05891944496808605 3.3109349062187166 2.8911458951917843e-05 4.5389299920796 0.4807688343913984 KFPVTENSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KFPVTENSK 9 1 P43490;A0A0C4DFS8 P43490 NAMPT Nicotinamide phosphoribosyltransferase 0 86.344 0.023566 0.0 47175.0 38161.0 42470.0 44646.0 50977.0 31086.0 42007.0 47478.0 42777.0 34905.0 False True 55160.79575127859 41949.37188273702 43482.64586837191 42144.62936428495 40988.42279145641 29455.795436224576 38027.79285565671 46231.75280709919 43402.532698866824 41233.000192172025 1.3377827345619813 1.0173737464464445 1.0545593496887227 1.022109212714674 0.9940684063838254 0.714374294835249 0.9222659684821137 1.121231843223384 1.0526164115291974 1.0 15.331511817852665 -2.0142477070610565 1.0929995884286272 0.9717779876781014 199.982321162326 0.5044440222333856 0.1037954938116035 796.8256707704537 2.3307852408535186 0.03480085826337836 395835.4645985035 0.009677257403950515 2.0142477070610565 199.0105431746479 KFS(ph)AACNFSNILVNQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KFSAACNFSNILVNQER 17 1 Q7L9B9 Q7L9B9 EEPD1 Endonuclease/exonuclease/phosphatase family domain-containing protein 1 1 KFS(0.997)AACNFS(0.003)NILVNQER 53.519 0.027852 4441800.0 15832.0 17353.0 15763.0 13479.0 24670.0 10748.0 12638.0 15016.0 11460.0 10732.0 True False 18512.044903746526 19075.691158018282 16138.849701510397 12723.815329507608 19836.090595076803 10184.35595922736 11440.837148803525 14621.845910767126 11627.580819810035 12677.626645534747 1.4602137625078864 1.5046736815472501 1.273018219636145 1.0036433226237287 1.5646533179823037 0.8033330089283269 0.902443136139615 1.1533582995928628 0.917173312080889 1.0 13.62999706609932 -5.540276116415419 0.5376664623010673 0.9660272099259997 1.6509767536615407 0.47552752766531703 0.18995964132573848 1.8478965150677469 0.7178689912783703 0.12799356379646676 0.7253684793366776 2.882198471895612e-06 5.540276116415419 0.6849495437355411 KFS(ph)AACNFSNILVNQER ddPTM_PC-9_Lapatinib_30min_R1 1 KFSAACNFSNILVNQER 17 1 Q7L9B9 Q7L9B9 EEPD1 Endonuclease/exonuclease/phosphatase family domain-containing protein 1 1 KFS(1)AACNFSNILVNQER 95.307 0.00076238 5151500.0 34706.0 31066.0 16001.0 8545.6 14686.0 9562.0 9941.7 11326.0 21464.0 7889.2 True False 34211.086075699095 30994.06858568934 14685.459545646178 9174.071931285918 13822.19835378691 9153.055550110694 10456.432580888299 11852.247307595802 19046.498294059827 9252.837708301779 3.6973615180783317 3.3496825041987948 1.587130349478644 0.9914873923547594 1.4938334367829056 0.9892160479480193 1.13007845922842 1.2809310701474637 2.058449407036615 1.0 13.175680171356303 -5.262115347918359 3.286255559613605 1.2777543778131113 3.6409563454347125 0.8950050084678849 0.304980968713413 0.06715673469126723 1.5113056832095242 0.08110833593027185 0.22889401684644722 5.468706956231493e-06 5.262115347918359 2.363201967621601 KFS(ph)EPNTYIDGLPSQDR ddPTM_PC-9_AZD4547_30min_R2 2 KFSEPNTYIDGLPSQDR 17 1 Q8N4X5-2;Q8N4X5;Q8N4X5-4;Q8N4X5-3 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 KFS(1)EPNTYIDGLPSQDR;KFS(0.956)EPNT(0.044)YIDGLPSQDR 173.49 1.0064e-05 13286700.0 32865.0 32534.0 35301.0 35758.5 34461.0 37802.0 34361.0 44367.0 38031.0 28100.0 True False 43315.38636553363 43049.9792629544 34832.885674736346 27514.93028831775 29676.684990159196 35438.234964147305 37419.06243392279 37511.09960223493 40041.24101817468 27116.227552974324 1.5973972146720112 1.5876094555871338 1.2845771266186177 1.0147034735773817 1.094425282137154 1.30690137095638 1.3799508932730713 1.3833450663058922 1.4766523455355294 1.0 14.726868862257415 -5.277072096834163 5.119563386669805 1.2485353816830644 1.5967306979850386 0.4593221535839488 0.15213465146874708 0.16351930862790243 13.571941977812491 0.04336238894128245 0.1023137966730169 5.283575323381746e-06 5.277072096834163 0.3481953163019742 KFS(ph)EPNTYIDGLPSQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KFSEPNTYIDGLPSQDR 17 1 Q8N4X5-2;Q8N4X5;Q8N4X5-4;Q8N4X5-3 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 KFS(0.999)EPNT(0.001)YIDGLPSQDR;KFS(1)EPNTYIDGLPSQDR 122.44 0.00019688 6402600.0 18217.6 26287.9 20276.4 15645.9 16727.0 9033.6 15066.6 9165.8 9927.4 9746.2 True False 21301.479865998783 28897.588981321318 20759.866274675212 14769.310947692195 13449.464425774207 8559.862113256075 13639.382575262156 8925.207461967853 10072.569444204379 11513.108909123246 1.850193551901434 2.509972693685041 1.8031503426693574 1.2828256089880867 1.1681870233257803 0.7434883297658244 1.1846828413526083 0.7752213179270213 0.8748783255426906 1.0 13.490989839617777 -5.793550109091482 1.7265578171938532 0.9397714530508448 2.201489115912626 0.8557430071447134 0.20464037911431204 0.11713018117065857 0.7117263730667573 0.062188836616582435 0.1268112422119545 1.6086067654132242e-06 5.793550109091482 1.2617176628617814 KFS(ph)EPNTYIDGLPSQDR ddPTM_PC-9_Lapatinib_30min_R1 3 KFSEPNTYIDGLPSQDR 17 1 Q8N4X5-2;Q8N4X5;Q8N4X5-4;Q8N4X5-3 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 KFS(0.993)EPNT(0.005)Y(0.002)IDGLPSQDR;KFS(1)EPNTYIDGLPSQDR;KFS(0.997)EPNT(0.002)YIDGLPS(0.001)QDR 114.58 0.00024238 64978200.0 191301.0 184900.0 181176.0 161693.0 186071.0 155037.0 156420.0 157396.0 180241.0 184408.0 True False 188573.01265969308 184471.8754102222 166280.408639585 173584.44261203601 175126.66960966127 148406.42891889895 164518.66223106187 164709.19276234767 159940.3605581271 216282.6770917852 0.8718821830546659 0.8529202518236665 0.7688105717732518 0.8025813483821957 0.8097119564288623 0.6861688181153722 0.7606649984327875 0.7615459313574569 0.7394968598906895 1.0 17.722558593390943 -5.188979567658423 4.352452809440438 0.7787689293339397 0.8670353476124261 0.10218633018349166 0.078362664961997 0.3907327324626771 14.11329389712368 0.01893597896148015 0.05458503879269574 6.4717306271619125e-06 5.188979567658423 0.08826641827848636 KFS(ph)NSLK ddPTM_PC-9_AZD4547_30min_R2 1 KFSNSLK 7 1 Q9BV36;H7C052;H7C3K9;Q9BV36-5;H7C190;H7C371;Q9BV36-2;Q9BV36-3 Q9BV36;Q9BV36-2 MLPH Melanophilin 1 KFS(0.992)NS(0.008)LK 56.547 0.041612 30745000.0 142840.0 148280.0 153530.0 210960.0 219050.0 183530.0 153680.0 209120.0 126290.0 165960.0 True False 188260.1487434301 196208.61022655942 151494.0918852802 162326.43129950954 188638.6885782293 172053.84008703093 167357.2222823916 176805.30909954128 132965.43157385496 160149.79091429253 1.1755254107336388 1.2251568304048834 0.9459524799901575 1.0135912783450456 1.1778890718576285 1.0743307194144829 1.0450043133178755 1.1039996249146669 0.8302566666790977 1.0 17.289062389020778 -1.5228787452803376 0.2328937426024192 0.9836678662581838 2.1219087595033375 0.2790541514263307 0.09622150920858019 75.98331049693203 1.000775012311952 0.14250849598678586 33.101755740816145 0.029999999999999995 1.5228787452803376 1.1382408932451535 KFSEPNT(ph)YIDGLPSQDR ddPTM_PC-9_AZD4547_30min_R2 1 KFSEPNTYIDGLPSQDR 17 1 Q8N4X5-2;Q8N4X5;Q8N4X5-4;Q8N4X5-3 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 KFS(0.044)EPNT(0.546)Y(0.379)IDGLPS(0.032)QDR 80.87100000000001 0.018635 9258200.0 17445.0 20144.0 13888.0 10608.0 13982.0 15113.0 15482.0 18041.0 17413.0 17992.0 True False 22992.14712145852 26655.154062610003 13703.836045741997 8162.489491966238 12040.840646887957 14167.981720891969 16859.868007391888 15253.177990937404 18333.415630655938 17362.10555633858 1.3242718198464423 1.535248934878103 0.7892957453388469 0.4701324655284258 0.6935126968221933 0.8160290049451694 0.9710727741334727 0.8785327298836029 1.055944255791185 1.0 14.083654298039582 -5.26592593455138 24.940189123002078 0.8161727940365489 1.4297604015993195 0.670939969226524 0.16641306450620108 197.9446712525981 1100355.5480848805 0.04717165808232837 0.10386923179357732 5.4209333219871645e-06 5.26592593455138 0.6135876075627706 KFSEPNT(ph)YIDGLPSQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KFSEPNTYIDGLPSQDR 17 1 Q8N4X5-2;Q8N4X5;Q8N4X5-4;Q8N4X5-3 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 KFS(0.042)EPNT(0.753)Y(0.013)IDGLPS(0.192)QDR 138.98 0.00025552 6826800.0 17351.0 27023.0 22142.0 16066.0 15419.0 9523.6 15021.0 7970.8 9372.2 8641.1 True False 20288.181602128992 29705.664851214657 22669.949254002604 15165.874106674766 12397.757636217633 9024.165650660374 13598.102137377567 7761.574945760698 9509.250694539578 10207.663027090035 1.9875442153886105 2.910133766404615 2.2208755514204386 1.4857342044330983 1.2145539682604456 0.8840579500627336 1.3321464571557342 0.7603674734522796 0.9315796053712837 1.0 13.317364988650219 -5.877408499898714 1.957112769931868 1.0090847790862334 2.4887366510062416 0.8480546265700823 0.2570264301366956 0.11171724163130484 0.8719246202281514 0.07843705939667964 0.13969567596774748 1.3261464898489933e-06 5.877408499898714 1.4796518719200082 KFSGFSAKPNNSGEAPS(ph)SPTPK ddPTM_PC-9_AZD4547_30min_R2 2 KFSGFSAKPNNSGEAPSSPTPK 22 2 P49916-4;P49916-3;P49916-2;P49916;K7ENR9;K7ERZ5 P49916-4 LIG3 DNA ligase 3 1 KFS(0.001)GFSAKPNNS(0.001)GEAPS(0.473)S(0.473)PT(0.052)PK;KFSGFSAKPNNS(0.001)GEAPS(0.474)S(0.474)PT(0.051)PK 42.395 0.029586 39602000.0 186805.0 148757.0 166356.0 217600.0 221920.0 196464.0 224780.0 199430.0 192400.0 234470.0 True False 246205.1042146209 196839.79114831617 164150.01074492058 167435.68188648677 191110.2386180361 184179.07502238578 244784.98454344008 168612.6759454933 202569.8712076152 226261.27666711318 1.0881451207262922 0.8699667660671633 0.7254887498333452 0.7400103294423926 0.8446440391088527 0.8140105887113824 1.0818686615278843 0.7452122538562559 0.8952918245292412 1.0 17.787630171102506 KFSGFSAKPNNSGEAPS(ph)SPTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KFSGFSAKPNNSGEAPSSPTPK 22 2 P49916-4;P49916-3;P49916-2;P49916;K7ENR9;K7ERZ5 P49916-4 LIG3 DNA ligase 3 1 KFSGFSAKPNNS(0.002)GEAPS(0.408)S(0.408)PT(0.183)PK;KFS(0.001)GFSAKPNNS(0.001)GEAPS(0.41)S(0.41)PT(0.177)PK 44.303999999999995 0.023009 33623000.0 111770.0 90194.0 98496.0 141069.0 135706.0 127521.0 133047.0 125045.0 126793.0 114554.0 True False 130690.45344187386 99147.86424861962 100844.51818815996 133165.3612818687 109115.38347367237 120833.57427210933 120443.82498313543 121762.70124612909 128647.1077562108 135321.733391035 0.9657757860980226 0.732682487609844 0.7452204140539103 0.984064850078922 0.8063404210051393 0.8929354601373625 0.8900552924125843 0.8998015189051355 0.9506758783857967 1.0 17.046034036866345 -8.026234982703826 0.4441575820084893 1.005052198669001 0.8270827899088723 0.28252289931853414 0.07720620856934166 1.2600053249033014 0.6670847070306182 0.08900835911661421 0.06015620593082211 9.413801083587829e-09 8.026234982703826 -0.1779694087601288 KFSGFSAKPNNSGEAPS(ph)SPTPK ddPTM_PC-9_Lapatinib_30min_R1 1 KFSGFSAKPNNSGEAPSSPTPK 22 2 P49916-4;P49916-3;P49916-2;P49916;K7ENR9;K7ERZ5 P49916-4 LIG3 DNA ligase 3 1 KFSGFSAKPNNS(0.002)GEAPS(0.487)S(0.487)PT(0.025)PK 46.099 0.019669 23727000.0 142990.0 113430.0 141560.0 119670.0 130020.0 139100.0 106730.0 107750.0 125030.0 112290.0 True False 140950.93637884522 113167.35980411869 129921.48323740247 128470.9310074174 122372.47922915535 133151.0172579374 112255.9571660991 112756.4583607142 110947.8047757315 131699.1768829801 1.0702491823778495 0.8592867661175464 0.9865018621402837 0.9754877292936225 0.9291818075513723 1.0110239138111494 0.8523664294868216 0.8561667660300014 0.8424335474344915 1.0 17.006886803246474 -7.27009250701327 24.965539138411955 0.8757555799107827 0.9657114526286995 0.27083399619579074 0.06606634010544608 781.368063462665 2254351.893638478 0.025644581485031227 0.017599324874732803 5.3691741794963717e-08 7.27009250701327 0.08995587271791683 KFSGFSAKPNNSGEAPSS(ph)PTPK ddPTM_PC-9_Lapatinib_30min_R1 1 KFSGFSAKPNNSGEAPSSPTPK 22 2 P49916-4;P49916-3;P49916-2;P49916;K7ENR9;K7ERZ5 P49916-4 LIG3 DNA ligase 3 1 KFSGFSAKPNNSGEAPS(0.132)S(0.828)PT(0.04)PK 65.47 0.00094526 24586000.0 138770.0 128360.0 125750.0 128710.0 122460.0 113880.0 100050.0 100430.0 125580.0 104980.0 True False 136791.11435269864 128062.79030641477 115411.32040903738 138175.76276397298 115257.14356562342 109009.61786724578 105230.09945159027 105096.34443774047 111435.85798397471 123125.65312294285 1.1109879288608575 1.04009836340557 0.9373458534575033 1.1222337446283623 0.936093662386809 0.8853526060763146 0.8546561726378532 0.8535698432624772 0.905058005034128 1.0 16.909771851836133 -6.461090004376937 5.391298465318808 0.8896794575513366 1.0432359346757094 0.5833201309912843 0.06090631795143757 0.15068945812940354 8.894554213224033 0.01896696666443219 0.021225372601413103 3.458676918312077e-07 6.461090004376937 0.15355647712437281 KFSKEEPVSS(ph)GPEEAVGK ddPTM_PC-9_AZD4547_30min_R2 1 KFSKEEPVSSGPEEAVGK 18 2 O00567 O00567 NOP56 Nucleolar protein 56 1 KFSKEEPVS(0.256)S(0.744)GPEEAVGK 75.773 0.015983 8389400.0 14230.0 7095.0 16642.0 35952.0 27460.0 13320.0 8995.9 10937.0 8155.2 20700.0 True False 18754.843997612752 9388.319999712967 16421.316206310374 27663.82185286297 23647.65299410266 12487.098294334743 9796.517672632515 9246.937957257487 8586.267222829225 19975.29930058963 0.9389017764083838 0.4699964620523029 0.8220811092340253 1.3849014944194797 1.1838447393579044 0.6251269683837052 0.49043158378825097 0.4629186185452819 0.42984423380208253 1.0 14.285929499535815 -6.907562989514741 7.194642801026838 0.5520902443592257 0.9476495400911653 0.30332123662634514 0.26807138504227285 0.29157063452106385 19.404598355000047 0.10269986172512433 0.0905461224088977 1.2371917362188814e-07 6.907562989514741 0.3955592957319396 KGAANAS(ph)GSSPDAPAK ddPTM_PC-9_AZD4547_30min_R2 1 KGAANASGSSPDAPAK 16 1 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 KGAANAS(0.561)GS(0.38)S(0.06)PDAPAK 66.777 0.011978 3265200.0 41901.0 48914.0 48752.0 47520.0 45095.0 54360.0 59064.0 66093.0 50818.0 49747.0 True False 55224.64640505779 64724.493934596205 48105.51662600907 36564.998176681336 38834.33764636051 50960.86060660936 64320.58157787073 55879.84551604829 53504.13573299678 48005.37267180833 1.1503847034498507 1.348276043539734 1.002086098880752 0.7616855393803562 0.8089581537436203 1.0615657742104496 1.33986214454791 1.1640331572483413 1.1145447427058026 1.0 15.550908258158497 -7.01342001349362 24.80975027037053 1.1729129556248443 1.0098371658447158 0.12505744423103737 0.17249428730385685 1235.5806345549845 2284232.7284759525 0.07231051885051772 0.05861576218177231 9.695718244625545e-08 7.01342001349362 -0.1630757897801285 KGAANAS(ph)GSSPDAPAKDAR ddPTM_PC-9_AZD4547_30min_R2 1 KGAANASGSSPDAPAKDAR 19 2 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 KGAANAS(0.402)GS(0.299)S(0.299)PDAPAKDAR 78.324 0.008817700000000001 7436600.0 9428.5 5037.0 12474.0 21156.0 18623.0 9532.7 6752.3 8459.9 8029.8 15862.0 True False 12426.566875016997 6665.111746096433 12308.58660963319 16278.811056941717 16037.517906379222 8936.6187620424 7353.241619061632 7152.616844162258 8454.238834838403 15306.676208017052 0.8118396643491052 0.43543821372568803 0.8041318992026775 1.0635105123877577 1.0477465968725062 0.5838379698240262 0.48039440562610747 0.4672873945302371 0.552323621401908 1.0 13.901873420139886 -6.891521191861415 12.701807994131718 0.5737024046224661 0.8216751712414893 0.18771088877200492 0.21480123349648886 0.7891193333348631 87.43615059198075 0.07983757824285662 0.07041456745498816 1.2837451272344887e-07 6.891521191861415 0.24797276661902312 KGAANASGS(ph)SPDAPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KGAANASGSSPDAPAK 16 1 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 KGAANAS(0.03)GS(0.485)S(0.485)PDAPAK;KGAANAS(0.026)GS(0.487)S(0.487)PDAPAK;KGAANAS(0.023)GS(0.488)S(0.488)PDAPAK 65.423 0.013059000000000001 22054900.0 176133.0 187622.0 191046.0 193948.0 239703.0 179708.0 211846.0 200634.0 191611.0 173164.0 True False 205948.8381146788 206247.87220939936 195601.2611859895 183081.7223478996 192734.91787238288 170283.79612214648 191778.41324777858 195367.57008929487 194412.94838260172 204557.2624345305 1.006802866168556 1.0082647262421687 0.9562176324519037 0.8950145312317902 0.9422052073759473 0.8324505035681468 0.9375292324766916 0.9550752085950659 0.9504084385408926 1.0 17.642145232842374 -5.409038240494322 3.4106889386758126 0.9251410009835972 1.0077745730425258 0.34416155109792546 0.04146641436478666 0.25298796626036196 5.38283424209807 0.01132090976001253 0.02616015263608808 3.899076530193797e-06 5.409038240494322 0.08263357205892863 KGAANASGS(ph)SPDAPAKDAR ddPTM_PC-9_Lapatinib_30min_R1 1 KGAANASGSSPDAPAKDAR 19 2 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 KGAANAS(0.208)GS(0.396)S(0.396)PDAPAKDAR 64.76100000000001 0.031105 8911100.0 21981.0 4640.1 11565.0 7401.4 5837.4 6455.8 3885.8 4208.1 7604.2 4697.8 True False 21667.54690917829 4629.356133536893 10614.170342190997 7945.723646346606 5494.055608769963 6179.700483204833 4086.987710634578 4403.623688424327 6747.734920224078 5509.8084705749725 3.932540854168237 0.8402027326829746 1.9264136673490144 1.4421052362855429 0.9971409420328969 1.1215817239759616 0.7417658404028122 0.799233532697515 1.2246768569652156 1.0 12.427786454029437 -4.757769210488408 24.99560493942223 1.1346124780559155 3.93254482855417 0.8638891377608384 0.3347069350146377 38.807480048809445 264258.3686550993 0.08960084151823396 0.6474179323907787 1.74675015116925e-05 4.757769210488408 2.7979323504982547 KGAANASGSS(ph)PDAPAK ddPTM_PC-9_AZD4547_30min_R2 3 KGAANASGSSPDAPAK 16 1 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 KGAANAS(0.003)GS(0.212)S(0.785)PDAPAK;KGAANAS(0.003)GS(0.015)S(0.982)PDAPAK;KGAANAS(0.02)GS(0.094)S(0.886)PDAPAK 159.69 7.799e-05 46911000.0 243553.0 223786.9 269797.0 245304.0 262404.2 300977.0 229843.5 316206.0 219924.0 292106.0 True False 320997.7877828937 296121.6390336523 266219.31549777207 188752.9527090204 225973.9062561952 282156.86061065993 250299.12623414086 267343.62839101837 231548.7336562552 281879.45785014733 1.1387768027904412 1.0505257860651782 0.9444438325807321 0.6696229450298049 0.8016685854998606 1.0009841183980852 0.8879651186472935 0.9484324626917067 0.8214459309033831 1.0 18.104718818831245 -5.243490168311457 2.9234689170654247 0.8732094840875669 1.1150522026216347 0.452975827239848 0.09537448746495067 0.24408534204196106 4.136288255294826 0.026837569226217446 0.0832705052670639 5.708339987366103e-06 5.243490168311457 0.2418427185340678 KGAANASGSS(ph)PDAPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 KGAANASGSSPDAPAK 16 1 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 KGAANAS(0.001)GS(0.034)S(0.964)PDAPAK;KGAANAS(0.005)GS(0.286)S(0.709)PDAPAK;KGAANAS(0.026)GS(0.264)S(0.709)PDAPAK;KGAANAS(0.045)GS(0.022)S(0.934)PDAPAK 199.33 1.1827e-50 62790300.0 114493.0 105169.0 118883.0 130835.0 135545.0 99306.6 115544.0 112431.0 102756.0 83454.5 True False 133874.4035601726 115609.4832822928 121717.62158628824 123504.73912279317 108985.9302679238 94098.78707672202 104598.83585388152 109479.8053804915 104258.61210474715 98584.14022454146 1.3579710007639343 1.1726986005961337 1.2346572309608472 1.2527850711229105 1.1055117995621868 0.9545022846717197 1.0610107834347453 1.1105214807486619 1.0575596832034153 1.0 16.58906795049557 -6.37199289724543 3.7200356074958076 1.0439316267415215 1.247710955029488 0.7585383114748305 0.057830212868918415 0.12633189724720562 3.1573522955812336 0.01877340540272598 0.02155393058889582 4.246265085273217e-07 6.37199289724543 0.20377932828796652 KGAANASGSS(ph)PDAPAK ddPTM_PC-9_Lapatinib_30min_R1 3 KGAANASGSSPDAPAK 16 1 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 KGAANAS(0.014)GS(0.173)S(0.813)PDAPAK;KGAANASGS(0.044)S(0.955)PDAPAK;KGAANAS(0.044)GS(0.179)S(0.777)PDAPAK 97.223 0.0010166 120070400.0 65081.0 82840.0 93755.0 83493.0 84856.0 80791.0 80729.0 82262.0 86663.0 64816.0 True False 64152.93300560631 82648.18906967461 86046.82580476587 89633.35374448319 79864.93691331487 77335.75726301954 84908.75260996926 86084.19283219543 76902.10033815254 76019.35923810877 0.8439025749304951 1.087199233169053 1.1319067493748396 1.1790858886843876 1.0505868204329498 1.0173166156371765 1.116935915547736 1.1323982955783864 1.0116120565720481 1.0 16.21407924442443 -4.761458959780889 11.033941765820751 1.0878279742592756 0.8433340906431837 0.6027712305884938 0.05743353479758778 0.04434247293843786 185.40851000956448 0.014429019157789751 0.08102403845190619 1.7319726920060978e-05 4.761458959780889 -0.24449388361609192 KGAANASGSS(ph)PDAPAKDAR ddPTM_PC-9_AZD4547_30min_R2 1 KGAANASGSSPDAPAKDAR 19 2 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 KGAANASGS(0.259)S(0.741)PDAPAKDAR 105.57 0.00066876 6889700.0 7712.2 5368.4 12766.0 23884.0 18214.0 9412.2 5928.1 10588.0 6760.2 12219.0 True False 10164.519176274709 7103.630315216223 12596.714498843778 18377.912804121574 15685.300496525335 8823.653646091403 6455.689415748602 8951.867888035327 7117.53037077817 11791.216529174142 0.8620416011465302 0.6024510106858127 1.0683133896894057 1.5586104078956105 1.3302529435971553 0.7483242822536321 0.5474998614244564 0.7591979899517898 0.6036298589859483 1.0 13.525424951986336 -6.888767179061968 7.9192607515077675 0.6994351979320333 1.0822074416865268 0.30726384951139074 0.263391941533416 0.3250334847947165 21.450517902513457 0.10465120491129974 0.09231922266264113 1.2919116689578997e-07 6.888767179061968 0.3827722437544935 KGAANASGSS(ph)PDAPAKDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KGAANASGSSPDAPAKDAR 19 2 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 KGAANAS(0.008)GS(0.246)S(0.746)PDAPAKDAR;KGAANAS(0.002)GS(0.217)S(0.781)PDAPAKDAR 123.61 7.1832e-05 10198700.0 25953.0 7325.4 14873.800000000001 31977.0 31380.0 41260.0 27074.0 44565.0 37938.0 30283.0 True False 30346.33030488466 8052.6173001179695 15228.447801200624 30185.43236083277 25231.314263214823 39096.25296592121 24509.354721214335 43395.21597052058 38492.7714783554 35773.06817990391 0.8483010222179431 0.22510278569400585 0.4256958817347249 0.8438032826546848 0.7053159135337717 1.0928962751896174 0.685134263517907 1.213069445211818 1.0760265595551943 1.0 15.126586240071656 -6.305292820963232 1.0571642013583806 1.0279922684212146 0.47686009683607244 0.497918086811451 0.20879553915707502 0.4135822416351908 0.9713834910464537 0.0929580848754196 0.13522481018082697 4.951162484914542e-07 6.305292820963232 -0.5511321715851422 KGAANASGSS(ph)PDAPAKDAR ddPTM_PC-9_Lapatinib_30min_R1 1 KGAANASGSSPDAPAKDAR 19 2 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 1 KGAANAS(0.004)GS(0.072)S(0.924)PDAPAKDAR 96.46700000000001 0.0018455 8816200.0 29456.0 8762.2 12175.0 10339.0 7302.6 8774.0 5617.5 3088.6 10759.0 5883.7 True False 29035.952038431158 8741.91166424797 11174.018496859091 11099.364549892935 6873.075425463995 8398.756473192969 5908.3466633614025 3232.107631488647 9547.208122707307 6900.689705462553 4.20768840184865 1.2668170918231425 1.6192611135686612 1.608442782336196 0.9959983304311308 1.2170894260822296 0.8561965420187468 0.4683745784033914 1.3835150586686693 1.0 12.752524847266418 -3.1780857930793056 1.3380166579616466 1.084346629845107 199.99999999998883 0.8690852733247334 0.3521789780536525 32.4105756555823 1.1711501469700178 0.10594184927649174 18875.73848364125 0.000663611963652827 3.1780857930793056 198.91565337014373 up KGAGDGS(ph)DEEVDGK ddPTM_PC-9_AZD4547_30min_R2 11 KGAGDGSDEEVDGK 14 1 P35579;P35579-2 P35579 MYH9 Myosin-9 1 KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK 184.92 1.1867999999999998e-28 1304116000.0 1443789.0 1825830.0 1347149.0 1081547.8 1229870.0 1584613.0 1722959.0 1655198.0 1758913.0 1396579.0 True False 1902883.8693232127 2415993.8414483354 1329284.9240484817 832213.6644569393 1059123.779601493 1485526.8986096603 1876299.0131861453 1399425.181766179 1851885.5502879417 1347685.194295567 1.4119646616121262 1.7926989564585754 0.9863467593730574 0.6175133985143586 0.7858836648829516 1.1022803432860617 1.3922383514548322 1.0383917458540133 1.3741232434151058 1.0 20.36205210614876 -5.270640730174547 24.812709843450346 1.0295228384903456 1.6023318123679313 0.47698499325202437 0.23664557098993924 474.7442721349436 1280215.6681177095 0.06773267282378695 0.14418782916955125 5.362400783315315e-06 5.270640730174547 0.5728089738775857 KGAGDGS(ph)DEEVDGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 20 KGAGDGSDEEVDGK 14 1 P35579;P35579-2 P35579 MYH9 Myosin-9 1 KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK 159.44 9.0364e-09 1325085500.0 1366394.2 2239669.0 1333760.7 1519002.4 1589147.0 1107557.6 1636982.0 1100377.0 1045461.8999999999 1129256.2 True False 1597697.7505443953 2462008.536863232 1365562.6134036216 1433897.620200226 1277765.053137188 1049475.3297122773 1481915.2142366413 1071493.2696958042 1060749.802467904 1333981.4098728367 1.1976911662484844 1.8456093305662526 1.0236743955328398 1.0749007516805755 0.9578582157745306 0.7867241042079588 1.1108964512315855 0.8032295366079694 0.7951758507406945 1.0 20.347307130845813 -5.403150088616475 6.152241618654782 0.9357553436206614 1.517869235972346 0.6238967106336213 0.18037375035452538 0.1320942389487626 6.0917128299517955 0.045220514442132674 0.09538294187884745 3.952300082092493e-06 5.403150088616475 0.5821138923516846 KGAGDGS(ph)DEEVDGK ddPTM_PC-9_Lapatinib_30min_R1 19 KGAGDGSDEEVDGK 14 1 P35579;P35579-2 P35579 MYH9 Myosin-9 1 KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK 181.86 1.9185e-05 1438266200.0 865286.1 1468723.8 1075396.1 1225343.0 1516590.5 1391055.9 1529761.0 1612520.2 1258557.5 1255240.8 True False 852946.9615399622 1465323.060279219 986981.1838069938 1315458.81184442 1427387.6285216433 1331563.681866683 1608964.539401941 1687443.775286411 1116805.5011519834 1472207.4997767704 0.5793659940390834 0.9953237301816522 0.6704090177211086 0.893528128367694 0.96955600941992 0.9044673947582709 1.092892503024137 1.1461996868935096 0.7585924547465787 1.0 20.489549595203762 -6.035739328767636 3.266659365830257 0.9875787424510297 0.77219338839815 0.3445051177672708 0.13960172857627812 0.2904021647903116 6.305802236382899 0.04092605900438491 0.0583780346475419 9.210022077067491e-07 6.035739328767636 -0.21538535405287973 KGAGDGS(ph)DEEVDGKADGAEAKPAE ddPTM_PC-9_AZD4547_30min_R2 2 KGAGDGSDEEVDGKADGAEAKPAE 24 3 P35579;P35579-2 P35579 MYH9 Myosin-9 1 KGAGDGS(1)DEEVDGKADGAEAKPAE;KGAGDGS(1)DEEVDGKADGAEAKPAE 61.111999999999995 0.0053536 145700000.0 207483.0 178900.0 187610.0 239340.0 253335.0 227248.0 186932.0 153720.0 205576.0 261420.0 True False 273458.2780855023 236725.92641982384 185122.1688178035 184163.8607661386 218163.80813040806 213038.14663596006 203568.58586473204 129966.10613418878 216442.3276682779 252267.76537005475 1.084000080963031 0.9383914987020542 0.7338320397227346 0.7300332664222332 0.8648104834574517 0.8444921463646048 0.8069544103905417 0.5151910944449833 0.8579864627205775 1.0 17.94459634578545 -4.996924618308861 3.0074456942825587 0.7797927124799153 1.0817311938558185 0.3689377510495363 0.11933754446132627 0.2744840331456459 4.699972203614571 0.030835899868167 0.15655395314797896 1.0071064599280337e-05 4.996924618308861 0.3019384813759032 KGAGDGS(ph)DEEVDGKADGAEAKPAE ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 KGAGDGSDEEVDGKADGAEAKPAE 24 3 P35579;P35579-2 P35579 MYH9 Myosin-9 1 KGAGDGS(1)DEEVDGKADGAEAKPAE;KGAGDGS(1)DEEVDGKADGAEAKPAE;KGAGDGS(1)DEEVDGKADGAEAKPAE;KGAGDGS(1)DEEVDGKADGAEAKPAE;KGAGDGS(1)DEEVDGKADGAEAKPAE 70.358 0.0009593999999999999 382975400.0 408012.0 302850.0 270915.0 471195.0 468503.0 396558.0 475116.0 507971.0 404951.0 375807.0 True False 477080.372995668 332914.94653407723 277374.64105085935 444795.4717848021 376703.20032692555 375761.80037953885 430109.5729380393 494637.29948976304 410872.6422829755 443937.8342134247 1.074655810404098 0.749913435794317 0.6248051408871597 1.0019318866410585 0.8485494393474563 0.8464288722886593 0.9688509061186765 1.1142039749015047 0.9255184186113927 1.0 18.75999814076171 -7.360007073985767 3.8405858012627854 1.0187760112717656 0.84808201325408 0.24768303468359254 0.1237464159461925 0.3259587275474621 8.732511626126227 0.05580373749286555 0.03638242487882142 4.365087221299421e-08 7.360007073985767 -0.1706939980176857 KGAGDGS(ph)DEEVDGKADGAEAKPAE ddPTM_PC-9_Lapatinib_30min_R1 15 KGAGDGSDEEVDGKADGAEAKPAE 24 3 P35579;P35579-2 P35579 MYH9 Myosin-9 1 KGAGDGS(1)DEEVDGKADGAEAKPAE;KGAGDGS(1)DEEVDGKADGAEAKPAE;KGAGDGS(1)DEEVDGKADGAEAKPAE;KGAGDGS(1)DEEVDGKADGAEAKPAE;KGAGDGS(1)DEEVDGKADGAEAKPAE;KGAGDGS(1)DEEVDGKADGAEAKPAE;KGAGDGS(1)DEEVDGKADGAEAKPAE;KGAGDGS(1)DEEVDGKADGAEAKPAE;KGAGDGS(1)DEEVDGKADGAEAKPAE;KGAGDGS(1)DEEVDGKADGAEAKPAE;KGAGDGS(1)DEEVDGKADGAEAKPAE;KGAGDGS(1)DEEVDGKADGAEAKPAE;KGAGDGS(1)DEEVDGKADGAEAKPAE;KGAGDGS(1)DEEVDGKADGAEAKPAE;KGAGDGS(1)DEEVDGKADGAEAKPAE 89.631 1.8488e-05 2578558300.0 1170688.0 951549.0 788672.0 812823.0 845413.0 821844.0 712616.0 735906.0 794835.0 715857.0 True False 1153993.7744421144 949345.7467534946 723830.4325219609 872600.7149180407 795687.4694859092 786695.6479319361 749511.7696231323 770098.8793169336 705312.3123163915 839591.9286305056 1.3744698288422605 1.1307228123333835 0.8621217139409997 1.0393152734821751 0.9477073830185447 0.9369976307599206 0.8927095938686466 0.9172299697700463 0.8400656179089963 1.0 19.67932877186641 -4.917409137255207 2.529360089019229 0.9299508795676412 1.409633014696756 0.8523130187005082 0.05805014106703928 0.1311646950033229 1.342749410344994 0.01519893485580675 0.12073062705796038 1.2094581983531549e-05 4.917409137255207 0.47968213512911473 KGAGSVFR ddPTM_PC-9_Lapatinib_30min_R1 1 KGAGSVFR 8 1 E9PKU4;P62917;E9PKZ0;E9PP36;G3V1A1 E9PKU4 RPL8 60S ribosomal protein L8 0 67.169 0.029776 2740700.0 23459.0 14353.0 16854.0 14020.0 17965.0 17025.0 16233.0 11064.0 20359.0 14251.0 False True 23124.47035814627 14319.7665103457 15468.329178321415 15051.077569348963 16908.334020548944 16296.88043721339 17073.46531132099 11578.073831117788 18065.955030225683 16714.26636173612 1.383516922470794 0.8567391592566613 0.925456663400613 0.9004928630194211 1.0116108990136174 0.9750281636364101 1.0214905603279831 0.6927060739933767 1.0808703558526491 1.0 14.028792411769901 -4.755314230831944 24.99944916426231 0.9349990363675934 1.3835176579771127 0.6233589360973548 0.10323193975249936 127.11130798577102 518747.5334683533 0.02441895125781224 0.2191646393684488 1.7566521402685815e-05 4.755314230831944 0.4485186216095193 KGDIFLVR ddPTM_PC-9_Lapatinib_30min_R1 1 KGDIFLVR 8 1 P55072;C9JUP7;C9IZA5 P55072 VCP Transitional endoplasmic reticulum ATPase 0 75.043 0.01704 7326500.0 52894.0 56436.0 55191.0 54516.0 58888.0 72432.0 57630.0 58366.0 57576.0 58085.0 False True 52139.72186042835 56305.32590941751 50653.40902342095 58525.28850004481 55424.3236182625 69334.25220723877 60613.79941424438 61077.897435558596 51091.18457784143 68124.91485660244 0.7653546719313828 0.8265012298060962 0.7435372085241115 0.859087877368154 0.8135690699199598 1.0177517631131265 0.8897449566260983 0.8965574131596751 0.749963279739642 1.0 16.055894901228626 -6.2534898618814205 2.0130874564680643 0.9005765462830391 0.787583299933614 0.3211937154888178 0.07572288956635242 0.4229956063727883 3.366756699367037 0.025657487576195546 0.03356372700801213 5.578406241541946e-07 6.2534898618814205 -0.11299324634942509 KGDIVDIK ddPTM_PC-9_Lapatinib_30min_R1 1 KGDIVDIK 8 1 P46778;M0R181;G3V1B3 P46778 RPL21 60S ribosomal protein L21 0 64.73 0.033988 11914000.0 74833.0 66295.0 82018.0 72718.0 77871.0 59543.0 65178.0 57288.0 73578.0 68780.0 False True 73765.86769730863 66141.49800065262 75274.79663863566 78065.92430013684 73290.78088027646 56996.48469151234 68552.59792159671 59949.80962012614 65290.87082931111 80668.53135641098 0.9144317673442585 0.8199169724365651 0.933137065630405 0.9677370219525225 0.9085423974865983 0.7065516594034614 0.8498059499647581 0.7431622791699894 0.8093722512542338 1.0 16.29971837015215 -6.648657739900235 24.999995360779895 0.8074685328083441 0.9084572777806604 0.2153277090568928 0.08073551976383873 9.80618896255298 2126.2762965748734 0.025442784762079798 0.02544277217863469 2.2456509859814509e-07 6.648657739900235 0.10098874497231636 KGDRS(ph)PEPGQTWTR ddPTM_PC-9_AZD4547_30min_R2 3 KGDRSPEPGQTWTR 14 2 Q09666;E9PJZ0;E9PKR9;E9PJC6;E9PLK4;Q09666-2 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 KGDRS(1)PEPGQTWTR;KGDRS(1)PEPGQTWTR;KGDRS(1)PEPGQTWTR 82.20200000000001 0.0030438 713013600.0 95456.2 121048.0 165111.0 213498.0 184696.0 151975.0 135839.0 178225.0 157739.0 198928.0 True False 125809.28598769665 160174.3987773439 162921.52025838918 164279.3346112188 159054.14848502522 142471.97922533928 147928.40784498834 150684.42145306928 166076.761509449 191963.59126897092 0.6553809769656697 0.834399886554084 0.848710524643763 0.8557838156978311 0.8285641429898316 0.7421822976093098 0.7706065867340312 0.7849635467693293 0.8651471896915575 1.0 17.55047318290086 -8.61811624616846 2.7437465506358603 0.9998002599688287 0.7949547007246105 0.5606560399879865 0.05687442414318624 0.312418293697644 5.356172160643471 0.0564147094493686 0.015130463509638434 2.4092604635878533e-09 8.61811624616846 -0.2048455592442182 KGDRS(ph)PEPGQTWTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 KGDRSPEPGQTWTR 14 2 Q09666;E9PJZ0;E9PKR9;E9PJC6;E9PLK4;Q09666-2 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 KGDRS(1)PEPGQTWTR;KGDRS(1)PEPGQTWTR;KGDRS(0.999)PEPGQT(0.001)WTR;KGDRS(1)PEPGQTWTR;KGDRS(1)PEPGQTWTR;KGDRS(1)PEPGQTWTR;KGDRS(1)PEPGQTWTR 101.2 0.0066051999999999994 910934000.0 314505.0 300898.0 417334.0 496867.0 575530.0 538994.0 517932.0 550776.0 485642.0 458410.0 True False 367744.4847431026 330769.1648743957 427284.825308008 469029.1528545486 462759.0279766734 510728.20579529187 468869.73145704303 536318.7135954109 492743.59550560033 541516.1042284364 0.6791016589748015 0.6108205504722387 0.7890528498996581 0.8661407282112713 0.8545618945830287 0.9431449993957026 0.8658463299537482 0.9904021494606687 0.9099334103972251 1.0 19.046644717432052 -5.561974619832158 0.8375291102309836 0.9410123530436953 0.5909779385918682 0.8457313236765079 0.047317470931514706 0.3455044415682243 0.38269449501722147 0.019300184698756075 0.09139352356733711 2.7417343941935292e-06 5.561974619832158 -0.35003441445182715 KGDRS(ph)PEPGQTWTR ddPTM_PC-9_Lapatinib_30min_R1 4 KGDRSPEPGQTWTR 14 2 Q09666;E9PJZ0;E9PKR9;E9PJC6;E9PLK4;Q09666-2 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 KGDRS(0.999)PEPGQTWTR;KGDRS(0.997)PEPGQT(0.002)WT(0.001)R;KGDRS(1)PEPGQTWTR;KGDRS(1)PEPGQTWTR 71.513 0.007966500000000001 947398000.0 168412.0 150633.0 167545.0 165878.0 177542.0 139515.0 132655.9 118363.0 161807.0 128118.4 True False 166010.4139970218 150284.21854336388 153770.0968424029 178077.22147278683 167099.32862100218 133548.2686753496 139524.17341169636 123862.57708537544 143582.59175675266 150263.494732963 1.1047953748982282 1.0001379164675872 1.0233363540204596 1.1850996929710191 1.1120420759410563 0.8887605663150691 0.9285300708575176 0.8243025180899373 0.9555387488619033 1.0 17.197135035490277 -6.763303672424744 24.998673572114015 0.9090142483596249 1.0824893565505511 0.6263041321703521 0.06371087119657515 32.81521998583182 440021.6181100582 0.022617910498319203 0.020967595724859987 1.7246315534066406e-07 6.763303672424744 0.17347510819092626 KGDS(ph)SAEELK ddPTM_PC-9_AZD4547_30min_R2 1 KGDSSAEELK 10 1 P26373;P26373-2 P26373 RPL13 60S ribosomal protein L13 1 KGDS(0.606)S(0.394)AEELK 56.138999999999996 0.039842 24878000.0 50124.0 53625.0 46232.0 51612.0 46145.0 54091.0 57384.0 53977.0 57149.0 54237.0 True False 66062.38935603248 70958.23255597016 45618.933472547855 39713.65079745111 39738.563270679755 50708.68121913368 62491.06483246196 45636.09491806601 60169.779468004155 52338.179138458 1.2622217746870363 1.3557642570685111 0.8716186581857439 0.7587893092801463 0.7592652997261025 0.9688659799376366 1.1939862230809561 0.8719465535348113 1.149634558528069 1.0 15.675576112998973 -5.259551482990785 24.864715871057363 0.9383990354453529 1.3089930480272332 0.5212992592400818 0.13866051875405133 121.27058168754114 1597172.545686125 0.038467298378517686 0.09168984220873372 5.501087045771232e-06 5.259551482990785 0.3705940125818803 KGDS(ph)SAEELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGDSSAEELK 10 1 P26373;P26373-2 P26373 RPL13 60S ribosomal protein L13 1 KGDS(0.587)S(0.413)AEELK 54.523999999999994 0.043063 10597000.0 15959.0 25156.0 17053.0 26579.0 28188.0 21274.0 27651.0 23171.0 24589.0 23257.0 True False 18660.543495382204 27653.321429787797 17459.608193862634 25089.864800280633 22664.763749251102 20158.353989263378 25031.697104096085 22562.785801703867 24948.567607182278 27473.309997689306 0.6792244362601989 1.0065522294952312 0.6355116363966011 0.9132450659345693 0.8249739019855039 0.7337431853300106 0.9111278221008471 0.8212620104239916 0.9081019946006005 1.0 14.745743117031799 -8.626564075551377 0.7395107891680315 1.0015382340046608 0.8092619829842306 0.24491389312879996 0.10564863655356578 1.1975498697222178 1.4374920693421542 0.09671935321936674 0.03635246523913275 2.3628487601250195e-09 8.626564075551377 -0.19227625102043022 KGDS(ph)SAEELK ddPTM_PC-9_Lapatinib_30min_R1 1 KGDSSAEELK 10 1 P26373;P26373-2 P26373 RPL13 60S ribosomal protein L13 1 KGDS(0.5)S(0.5)AEELK 79.089 0.019532 0.0 13510.0 17620.0 14544.0 18783.0 20051.0 15154.0 15209.0 19684.0 15917.0 14493.0 True False 13317.34492256943 17579.201972569575 13348.248461463547 20164.3644782512 18871.639601782736 14505.898745699378 15996.447601791471 20598.590499974922 14124.25984655936 16998.095739291388 0.7834609903853029 1.0341865490223678 0.7852790492648446 1.1862719676087554 1.1102208089204144 0.8533837535794522 0.9410729205869461 1.2118175362644257 0.8309318916183589 1.0 14.053085512891226 -4.025298142541913 1.2008728196590412 1.006305812750252 2.1437197778569136e-10 0.1550417434521647 0.14015909495256312 15.361843244277019 5.012637970456444 0.041067211058554695 29.95304449614345 9.434130022496544e-05 4.025298142541913 -1.00630581253588 KGDSS(ph)AEELK ddPTM_PC-9_AZD4547_30min_R2 1 KGDSSAEELK 10 1 P26373;P26373-2 P26373 RPL13 60S ribosomal protein L13 1 KGDS(0.183)S(0.817)AEELK 92.039 0.011293000000000001 18871000.0 21389.0 21873.0 24932.0 22171.0 20961.0 25539.0 25765.0 27024.0 20658.0 21608.0 True False 28190.257081162268 28943.01950017218 24601.3853897206 17059.818488535388 18050.926963196856 23942.042292718852 28058.03508658132 22848.061749741835 21749.93970585715 20851.510496963325 1.3519527559055116 1.3880538536710445 1.179837086301416 0.8181574419282414 0.8656891770898647 1.1482162069844106 1.3456116328199583 1.0957509170891613 1.0430870084459667 1.0 14.347864276770732 -5.43662805225649 4.4109169778321125 1.0547706330954771 1.3635256051320446 0.4616444603425769 0.138728105290264 0.2264615636384661 7.746548093386099 0.04227794256364222 0.09106564904183612 3.65908036221209e-06 5.43662805225649 0.30875497203656743 KGDVEGSQS(ph)QDEGEGSGESER ddPTM_PC-9_AZD4547_30min_R2 1 KGDVEGSQSQDEGEGSGESER 21 1 Q9UQE7 Q9UQE7 SMC3 Structural maintenance of chromosomes protein 3 1 KGDVEGS(0.003)QS(0.997)QDEGEGSGESER 97.395 0.000133 10093000.0 6639.9 6728.2 8890.9 14887.0 11229.0 10671.0 9135.8 11333.0 8741.5 12808.0 True False 8751.250081500277 8902.959072877911 8773.000856789138 11455.032151857216 9670.047176648899 10003.740683096541 9948.868501610308 9581.745256432221 9203.557843874052 12359.59581845179 0.7080530957521629 0.7203276873817003 0.7098129247634312 0.926812844053999 0.7823918612461719 0.8093906006345156 0.804950958570791 0.7752474593163895 0.7446487716154884 1.0 13.593343944778022 KGDVEGSQS(ph)QDEGEGSGESER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGDVEGSQSQDEGEGSGESER 21 1 Q9UQE7 Q9UQE7 SMC3 Structural maintenance of chromosomes protein 3 1 KGDVEGS(0.009)QS(0.991)QDEGEGSGESER 96.41 0.00014644 7309000.0 15482.0 12558.0 15049.0 16150.0 19828.0 17533.0 16864.0 18211.0 17322.0 14014.0 True False 18102.79681656164 13804.675247069292 15407.825233650314 15245.167859006448 15942.845736488967 16613.538614917503 15266.519835213052 17732.980546149454 17575.30147999559 16554.627265237046 1.093518840776052 0.8338862014765889 0.9307261943616879 0.920900701341653 0.9630446811670139 1.0035586032072232 0.9221904903453259 1.071179692664348 1.0616549197034384 1.0 14.014946907732396 -7.763060968615132 24.99995811692244 1.0498129971747792 0.9482920547622672 0.2922246113623064 0.06501522842794248 48.96989158825474 754919.0216525261 0.03217467328267629 0.01673998132480775 1.725595626511056e-08 7.763060968615132 -0.10152094241251197 KGDVEGSQS(ph)QDEGEGSGESER ddPTM_PC-9_Lapatinib_30min_R1 1 KGDVEGSQSQDEGEGSGESER 21 1 Q9UQE7 Q9UQE7 SMC3 Structural maintenance of chromosomes protein 3 1 KGDVEGS(0.012)QS(0.984)QDEGEGS(0.003)GESER 117.94 1.2372e-06 5030800.0 14684.0 12250.0 11809.0 10597.0 15669.0 11477.0 11233.0 11648.0 13476.0 9780.3 True False 14474.603467284194 12221.63587763775 10838.109604058238 11376.3387305557 14747.38022643926 10986.155464193727 11814.589776508874 12189.208603114601 11958.190971428914 11470.811823569418 1.2618639107602476 1.0654551801229613 0.944842420114403 0.991764044736607 1.2856439852092578 0.9577487307062389 1.0299698014601795 1.0626282420629611 1.0424886359706524 1.0 13.48567987834796 -4.769950479535074 4.894993426616755 1.043080780635229 1.2750847113784458 0.35156571743106835 0.08992287865169597 0.19790705194008715 11.983610393530917 0.022640597707622705 0.15679775448140384 1.698437305877906e-05 4.769950479535074 0.2320039307432169 KGEQGGPPPKAS(ph)PSTAGETPSGVK ddPTM_PC-9_AZD4547_30min_R2 2 KGEQGGPPPKASPSTAGETPSGVK 24 2 A0A087WW69;F8W8L6;A0A087WTA5;E7ERK9;Q9UI10-3;Q9UI10;Q9UI10-2 A0A087WW69 EIF2B4 Translation initiation factor eIF-2B subunit delta 1 KGEQGGPPPKAS(0.484)PS(0.359)T(0.13)AGET(0.024)PS(0.003)GVK;KGEQGGPPPKAS(0.567)PS(0.164)T(0.206)AGET(0.054)PS(0.009)GVK 53.96 0.0031176 75367000.0 204740.0 177581.0 193947.0 251708.0 227209.0 242284.0 197507.0 224803.0 180103.0 220650.0 True False 269843.0611434457 234980.58546427483 191375.1360572813 193680.60944983375 195664.95226282073 227133.94317902435 215084.74037824257 190064.86180902924 189622.87689243833 212925.1106606332 1.2673144107156538 1.1035832492241573 0.89879082586131 0.9096184515246211 0.9189378916171036 1.0667315962607982 1.0101426727496292 0.8926371399752877 0.8905613635897802 1.0 17.699986574012478 -4.965308671995186 2.912323849167857 0.9490758421230939 1.271446898568764 0.7565303314587095 0.05734275837336715 0.15206179799882988 2.3506452214519924 0.016406301233113277 0.09508469900306414 1.083156793686376e-05 4.965308671995186 0.32237105644567 KGEQGGPPPKAS(ph)PSTAGETPSGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KGEQGGPPPKASPSTAGETPSGVK 24 2 A0A087WW69;F8W8L6;A0A087WTA5;E7ERK9;Q9UI10-3;Q9UI10;Q9UI10-2 A0A087WW69 EIF2B4 Translation initiation factor eIF-2B subunit delta 1 KGEQGGPPPKAS(0.801)PS(0.137)T(0.058)AGET(0.003)PS(0.001)GVK;KGEQGGPPPKAS(0.942)PS(0.04)T(0.012)AGET(0.005)PSGVK 76.015 8.2451e-05 42652000.0 149662.0 141638.0 126267.0 152481.0 165170.0 152370.0 166957.0 140770.0 140123.0 117484.0 True False 174996.82064076036 155698.884587068 129277.68415026409 143937.98392007174 132806.12418276593 144379.44896794515 151141.6242959951 137074.9366581438 142172.03378832818 138782.91919716744 1.260939182235706 1.1218879490916907 0.9315100510791291 1.0371448068157476 0.9569342174888946 1.040325782186688 1.0890506207126958 0.9876931358058758 1.024420257267725 1.0 17.08247049259853 -4.937783172438686 3.3785826085970623 1.0112498444605666 1.260205537460986 0.7713942406092874 0.043013832869979306 0.11683331572659135 2.4988067567061347 0.01105017405925298 0.061262432977011325 1.1540292791864668e-05 4.937783172438686 0.2489556930004193 KGEQGGPPPKAS(ph)PSTAGETPSGVK ddPTM_PC-9_Lapatinib_30min_R1 2 KGEQGGPPPKASPSTAGETPSGVK 24 2 A0A087WW69;F8W8L6;A0A087WTA5;E7ERK9;Q9UI10-3;Q9UI10;Q9UI10-2 A0A087WW69 EIF2B4 Translation initiation factor eIF-2B subunit delta 1 KGEQGGPPPKAS(0.872)PS(0.077)T(0.031)AGET(0.015)PS(0.006)GVK;KGEQGGPPPKAS(0.94)PS(0.039)T(0.018)AGET(0.003)PS(0.001)GVK 50.891000000000005 0.0079919 62795000.0 101278.0 72041.0 81560.0 67850.0 74405.0 75877.0 58886.0 60855.0 73227.0 57282.0 True False 99833.75714788945 71874.19349068568 74854.45163070447 72839.91534096492 70028.64418585833 72631.91758792603 61934.82894858912 63682.54546209985 64979.40414550492 67183.11737653278 1.4859947118613703 1.0698252224269589 1.1141854464891399 1.0841996945858912 1.0423547897216139 1.0811037121253997 0.9218808439845201 0.9478950657378145 0.9671984076196258 1.0 16.035811119440407 -1.522878745280785 0.8697166381314644 1.0016117328412386 186.2057344415167 0.8426501274153018 0.059947434824272915 302.5313466343554 0.7662584741061773 0.02184109672823837 111009.54000667368 0.02999999999996909 1.522878745280785 185.20412270867547 KGESGQSWPR ddPTM_PC-9_Lapatinib_30min_R1 2 KGESGQSWPR 10 1 A0A087WYT3;Q15185-4;Q15185;Q15185-3;B4DDC6 A0A087WYT3 PTGES3 Prostaglandin E synthase 3 0 ; 68.847 0.025262 47806000.0 81330.0 84025.0 94375.0 71101.0 91472.0 72927.0 78963.0 80167.0 79651.0 69544.0 False True 80170.2192859047 83830.44527498046 86615.85179803488 76330.00472598277 86091.79680087125 69808.08221114014 83051.31777107372 83891.85148402186 70679.86561778598 81564.58773844474 0.9829047324187871 1.027779917723629 1.0619296216611571 0.9358228471742193 1.0555045907538212 0.8558626255182642 1.0182276411105824 1.0285327715140302 0.8665508841218805 1.0 16.31565530401332 -5.764458073377702 24.987681282800608 0.9683179896019158 1.0245622714555112 0.1452060464649353 0.06474779124920571 153.7892411234703 1273030.0338466468 0.017440897632112578 0.02717091460956582 1.7200533865157155e-06 5.764458073377702 0.05624428185359531 KGGEFDEFVNDDT(ph)DDDLPISK ddPTM_PC-9_AZD4547_30min_R2 3 KGGEFDEFVNDDTDDDLPISK 21 1 Q6PD62 Q6PD62 CTR9 RNA polymerase-associated protein CTR9 homolog 1 KGGEFDEFVNDDT(1)DDDLPISK;KGGEFDEFVNDDT(0.98)DDDLPIS(0.02)K;KGGEFDEFVNDDT(1)DDDLPISK 101.3 0.00065967 8859800.0 73127.0 73478.0 84332.0 103021.0 91808.0 84882.0 74048.0 89390.0 79635.0 86891.0 True False 96379.86486390917 97228.32655939527 83213.70257845 79271.10010858346 79062.04392143391 79574.3151216006 80638.1285500166 75576.82947785009 83844.34352192542 83848.97253756218 1.1494459854082706 1.1595649131638373 0.9924236405064165 0.9454033568875522 0.9429101100316543 0.9490195611634162 0.9617068177417772 0.9013447295850121 0.9999447934125288 1.0 16.35550548505588 -5.329316049113475 3.464514451946899 0.9530980825873386 1.1584464742186409 0.8872886808921542 0.027662286833518165 0.062295074459245904 1.4593227355314038 0.006995836027205332 0.01729403337441646 4.68472336702847e-06 5.329316049113475 0.20534839163130225 KGGEFDEFVNDDT(ph)DDDLPISK ddPTM_PC-9_Lapatinib_30min_R1 4 KGGEFDEFVNDDTDDDLPISK 21 1 Q6PD62 Q6PD62 CTR9 RNA polymerase-associated protein CTR9 homolog 1 KGGEFDEFVNDDT(0.997)DDDLPIS(0.003)K;KGGEFDEFVNDDT(0.999)DDDLPIS(0.001)K;KGGEFDEFVNDDT(0.998)DDDLPIS(0.002)K;KGGEFDEFVNDDT(1)DDDLPISK 125.23 5.691e-06 9285600.0 54394.0 45183.1 52683.0 45116.3 48975.5 45666.1 40103.8 44132.1 48686.6 37218.7 True False 53618.331585362066 45078.481307991395 48351.60710226098 48434.30320556483 46094.85737953768 43713.067355878426 42180.17853459957 46182.63847815195 43203.002415373296 43651.9027041996 1.2283160243597726 1.0326807885891889 1.1076632198579797 1.1095576642734781 1.055964448832675 1.0014011909651064 0.9662849938163532 1.057975382908312 0.9897163637546751 1.0 15.413756919133535 -1.5228787452866999 0.3221332652333917 0.9963255815654795 2.8144344443206246 0.6242845195784018 0.045178852216946064 41.03393979732941 0.5854177586551399 0.04325375629733631 44.05102382585846 0.029999999999560507 1.5228787452866999 1.8181088627551452 KGGS(ph)GMK ddPTM_PC-9_Lapatinib_30min_R1 1 KGGSGMK 7 1 A0A0J9YVW5;A0A0G2JMG3;O95255-3;O95255 A0A0J9YVW5 ABCC6 Multidrug resistance-associated protein 6 1 KGGS(1)GMK 71.223 0.015623 6648800.0 38070.0 75231.0 58899.0 62527.0 49162.0 55661.0 75703.0 66191.0 61509.0 49918.0 True False 37527.11481881702 75056.80724167878 54056.55157671489 67125.44416395744 46270.38781621084 53280.508782128316 79622.5309223761 69266.4755021256 54581.20870151533 58546.25978844599 0.640982275459088 1.2820085777109047 0.9233134921350324 1.1465368480670142 0.7903218409409344 0.910058285100616 1.3599934685851525 1.183106756134663 0.9322749036188106 1.0 15.837289387047628 KGGSYSQAASSDS(ph)AQGSDVSLTACKV ddPTM_PC-9_AZD4547_30min_R2 1 KGGSYSQAASSDSAQGSDVSLTACKV 26 2 Q53Z42;A0A140T9I0;A0A140T9X5;A0A140T913 Q53Z42 HLA-A 1 KGGSYSQAASSDS(0.995)AQGS(0.004)DVSLTACKV 109.59 1.3360999999999998e-09 5269400.0 9665.8 17456.0 17708.0 21040.0 15949.0 13715.0 14290.0 17838.0 12538.0 10876.0 True False 12739.323338870365 23098.310629314936 17473.180349798335 16189.553064759573 13734.75664977944 12857.398881891966 15561.782316601855 15081.546976461468 13200.733083165685 10495.234550396757 1.2138197843695426 2.200837963020249 1.6648680185177744 1.5425622921545428 1.3086660030156465 1.2250701801996327 1.4827474547496953 1.4369899885554565 1.2577835225861294 1.0 13.357446788286525 -5.993182420244712 2.4672952857777113 1.3141017466809273 1.7455321494736222 0.3400549518388678 0.25466924946012914 0.31404138035795165 3.847870284839588 0.07571906007516313 0.11592333425408878 1.0158219193007556e-06 5.993182420244712 0.43143040279269496 KGGSYSQAASSDS(ph)AQGSDVSLTACKV ddPTM_PC-9_Lapatinib_30min_R1 1 KGGSYSQAASSDSAQGSDVSLTACKV 26 2 Q53Z42;A0A140T9I0;A0A140T9X5;A0A140T913 Q53Z42 HLA-A 1 KGGSYS(0.001)QAAS(0.018)S(0.145)DS(0.807)AQGS(0.021)DVS(0.003)LT(0.004)ACKV 63.108999999999995 0.018559 0.0 17669.0 22112.0 10554.0 7566.6 10248.0 11759.0 4645.2 6886.0 14890.0 4555.8 True False 17417.036819902238 22060.801022557232 9686.290859618137 8123.073005437651 9645.232788343199 11256.09498156783 4885.705726861842 7205.9486985789135 13212.931401348804 5343.2639597780835 3.259625006552288 4.12871256007975 1.8128041085996485 1.520245502858335 1.8051200279358433 2.106595344399815 0.9143672788092533 1.3486042899662758 2.4728202650683877 1.0 12.383505573403628 -5.307310540910188 6.649679962704789 1.623616496861111 3.692448607888525 0.7433156048873912 0.48715211045366885 0.09285227306198113 10.810149661624372 0.12492673270287265 0.2675141845095266 4.9282128761764575e-06 5.307310540910188 2.068832111027414 KGGSYSQAASSDSAQGSDVS(ph)LTACK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGGSYSQAASSDSAQGSDVSLTACK 25 1 Q53Z42;A0A140T9I0;A0A140T9X5;A0A140T913 Q53Z42 HLA-A 1 KGGSYSQAASSDSAQGS(0.209)DVS(0.582)LT(0.209)ACK 70.889 0.0046037 0.0 3348.9 4728.7 4472.2 3643.2 6988.4 3712.4 5425.5 2942.0 3047.5 3092.3 True False 3915.8026262100016 5198.134085110413 4578.83420891295 3439.0833154137654 5619.073186649153 3517.7152086933047 4911.557362781573 2864.775617306664 3092.063922196429 3652.9095113666676 1.0719681432089396 1.423012004249081 1.2534759469582002 0.9414641410394797 1.5382459294883772 0.9629899666956758 1.3445603696172606 0.7842448898316295 0.8464660601569599 1.0 11.83483030085326 -7.766022196083679 24.999885083010163 0.8615165356110679 1.2202437572824314 0.41232232891880716 0.1870983254283666 105.66657498034482 576410.004574314 0.09238327958022396 0.04672731889225122 1.7138697121802337e-08 7.766022196083679 0.3587272216713635 KGGSYSQAASSDSAQGSDVS(ph)LTACKV ddPTM_PC-9_AZD4547_30min_R2 1 KGGSYSQAASSDSAQGSDVSLTACKV 26 2 Q53Z42;A0A140T9I0;A0A140T9X5;A0A140T913 Q53Z42 HLA-A 1 KGGSYSQAASSDSAQGS(0.01)DVS(0.904)LT(0.086)ACKV 132.9 3.2077999999999995e-10 4263600.0 14176.0 24992.0 22540.0 24971.0 25646.0 20105.0 26988.0 28515.0 19701.0 21947.0 True False 18683.673120882533 33070.17525480289 22241.104872625623 19214.321748104154 22085.49558218341 18847.83117174173 29389.87971731637 24108.661959513327 20742.354639611356 21178.642210146892 0.8821940960847341 1.5614870361688555 1.0501667034145228 0.9072499340348829 1.0428192403950256 0.8899452091745311 1.3877131227626762 1.138347856311706 0.979399643933429 1.0 14.370322478819295 KGHAVGDIPGVR ddPTM_PC-9_AZD4547_30min_R2 1 KGHAVGDIPGVR 12 1 D6RD47;P62266 D6RD47 RPS23 40S ribosomal protein S23 0 57.225 0.029082999999999998 4159500.0 40764.0 32739.0 49673.0 68395.0 52361.0 43436.0 43653.0 51832.0 39969.0 52252.0 False True 53726.104056126926 43321.241503960926 49014.30356423836 52627.58944221635 45091.57896664998 40719.940053507795 47538.032432933585 43822.55538086957 42081.67974166928 50422.67338427099 1.0655147863081458 0.8591619324467372 0.9720687197741491 1.0437286623250162 0.8942718808859507 0.8075720171197845 0.9427907971210974 0.8691041636546729 0.8345785123483035 1.0 15.621784990724551 -6.420760867876741 8.435828024321413 0.8820714998223381 0.9749393429071666 0.2810300341691949 0.07205631624975689 0.4243064905279195 31.817178681945094 0.021728732177492403 0.024623072598390985 3.795239016847559e-07 6.420760867876741 0.09286784308482843 KGHAVGDIPGVR ddPTM_PC-9_Lapatinib_30min_R1 2 KGHAVGDIPGVR 12 1 D6RD47;P62266 D6RD47 RPS23 40S ribosomal protein S23 0 ; 77.67399999999999 0.0068671999999999995 9902100.0 112410.0 96643.0 119713.0 101383.0 98427.0 113845.0 90877.0 91341.0 118158.0 96728.0 False True 110807.01278653089 96419.2290712284 109870.65924554336 108839.04402377366 92637.71737492741 108976.11473565699 95582.16639542386 95585.03631671453 104849.80178109944 113447.3059180415 0.9767267004699252 0.8499032065237864 0.9684730576583102 0.9593797150405933 0.816570447621315 0.9605879474509984 0.8425247794291028 0.8425500768239368 0.9242158809557521 1.0 16.791662823554326 KGKGAS(ph)S(ph)STNDAS(ph)DPTTK ddPTM_PC-9_AZD4547_30min_R2 1 KGKGASSSTNDASDPTTK 18 2 J3QQJ4;O75976-2;O75976 J3QQJ4 CPD Carboxypeptidase D 3 KGKGAS(0.619)S(0.619)S(0.619)T(0.145)NDAS(0.987)DPT(0.008)T(0.002)K 51.265 0.045788 0.0 441.08 494.75 2818.8 3054.6 3408.5 2532.3 953.56 2643.1 1102.0 2406.6 True False 581.3342649660605 654.6682621364324 2781.4208702288 2350.409163099554 2935.2886099926777 2373.9548806864764 1038.424992709508 2234.669627395747 1160.2494702224112 2322.3456665120284 0.25032202283615107 0.28189957747318906 1.1976773786678643 1.0120841169306525 1.2639326919843241 1.0222228821999444 0.44714488789652773 0.9622467747241246 0.49960240069042355 1.0 11.181367008910067 -5.2443610712604505 23.76969095985888 0.9257987259409102 0.266110429799009 0.527608025330917 0.2496159221006435 349.79578443359253 486843.5716938666 0.06673647802663926 0.17540222608629874 5.696904362434733e-06 5.2443610712604505 -0.6596882961419012 KGKNSIDASEEK ddPTM_PC-9_Lapatinib_30min_R1 1 KGKNSIDASEEK 12 2 A0A0B4J1V9;Q9NRZ9-6;Q9NRZ9-5;Q9NRZ9-3;Q9NRZ9-2;Q9NRZ9;Q9NRZ9-4;B1ALG6;Q9NRZ9-9;Q9NRZ9-8;Q9NRZ9-7 A0A0B4J1V9 HELLS Lymphoid-specific helicase 0 40.015 0.0419 1817800.0 7627.7 10988.0 6731.6 10689.0 8761.9 8660.7 10836.0 9390.5 5986.7 10042.0 False True 7518.927599251136 10962.557961100705 6178.153832727444 11475.104717458706 8246.542268558187 8290.302050077777 11397.035059044792 9826.816911705671 5312.414803254188 11777.74631987609 0.6384012182841988 0.9307857091980597 0.524561632160578 0.9743039462561146 0.7001799872902124 0.7038954503619327 0.9676753726484318 0.8343546078184724 0.4510552918166502 1.0 13.523775884405858 -5.770079043729438 24.9999773434799 0.7958540894090839 0.7212031187433154 0.06162973966002083 0.18178829489917428 767.4444872659377 2220702.4962143246 0.049524647025159206 0.07478230197131727 1.6979345918994822e-06 5.770079043729438 -0.07465097066576842 KGLAS(ph)PTAITPVASPICGK ddPTM_PC-9_AZD4547_30min_R2 2 KGLASPTAITPVASPICGK 19 1 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425;A0A0J9YWY6 O95425-2 SVIL Supervillin 1 KGLAS(0.974)PT(0.026)AITPVASPICGK;KGLAS(0.989)PT(0.011)AITPVASPICGK 117.22 2.8976e-05 43874000.0 150088.0 138073.0 209447.0 301430.0 284120.0 247947.0 183162.0 259520.0 193253.0 221731.0 True False 197812.86197566404 182702.3970853231 206669.59592976145 231939.97054707602 244674.8422681877 232442.8348938002 199463.06316818963 219417.147176325 203467.95904618117 213968.26517966375 0.9244962649464189 0.8538761434174011 0.9658890104858597 1.0839923871529353 1.1435099595855507 1.0863425690656687 0.9322086291661315 1.0254658418251228 0.9509258715320904 1.0 17.707037312825058 -5.512563234779297 4.915958089432514 1.0354139371704485 0.8919477977866985 0.4583471211295983 0.06195414704143771 0.16758587182343013 11.40150310333617 0.01837251946038941 0.03616279053413794 3.0721100228515878e-06 5.512563234779297 -0.14346613938374997 KGLAS(ph)PTAITPVASPICGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGLASPTAITPVASPICGK 19 1 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425;A0A0J9YWY6 O95425-2 SVIL Supervillin 1 KGLAS(0.922)PT(0.075)AIT(0.003)PVASPICGK 63.522 0.0058726 12609000.0 72232.0 54574.0 68504.0 97901.0 131860.0 132160.0 142410.0 133560.0 131680.0 108860.0 True False 84459.45095296988 59991.746052998904 70137.3951628668 92415.92436932435 106022.97956493002 125229.29694561654 128919.89384088528 130054.19151851744 133605.57088591476 128595.4562647141 0.6567840995805472 0.4665152859639592 0.5454111459310722 0.7186562189186989 0.8244690959117671 0.9738236527411334 1.0025229318795164 1.0113435987256076 1.0389602771880784 1.0 16.972480142451253 -6.31496008039335 1.2787531224690483 1.0172838251443082 0.5401482551712103 0.9396031099286972 0.04982672552481458 0.0939534364717836 0.3137779172518927 0.01997909532028989 0.027196524313974523 4.842168739262115e-07 6.31496008039335 -0.4771355699730978 KGLAS(ph)PTAITPVASPICGK ddPTM_PC-9_Lapatinib_30min_R1 2 KGLASPTAITPVASPICGK 19 1 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425;A0A0J9YWY6 O95425-2 SVIL Supervillin 1 KGLAS(0.976)PT(0.024)AITPVASPICGK;KGLAS(0.989)PT(0.011)AITPVASPICGK 129.9 1.7139e-05 27969000.0 193847.0 127351.0 154703.0 134650.0 184981.0 201542.0 180262.0 194527.0 225960.0 171018.0 True False 191082.70623281415 127056.12658392216 141983.91651084946 144552.61017923255 174100.78126663863 192922.51847734852 189595.08433125983 203565.43457572724 200510.00533571388 200578.2334328392 0.9526592340678657 0.6334492253191826 0.7078730033704819 0.7206794461455558 0.8679943894556925 0.9618317759386684 0.9452425673832804 1.0148929477130342 0.999659842965223 1.0 17.613805528929653 -6.559137468198174 2.2352512367731645 0.9869598863350098 0.7413370801384016 0.6559876302771555 0.07849092269914804 0.18194699286340607 1.8382766993348305 0.028231851466174733 0.029671966460619793 2.759704182652545e-07 6.559137468198174 -0.24562280619660815 KGLGGSDGEPASGS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 KGLGGSDGEPASGSPK 16 1 Q9H6A9;Q9H6A9-3 Q9H6A9 PCNXL3 Pecanex-like protein 3 1 KGLGGSDGEPAS(0.064)GS(0.936)PK 74.325 0.006081800000000001 2643000.0 36043.0 37784.0 14018.0 11386.0 16515.0 12300.0 11700.0 9377.5 15724.0 7503.1 True False 35529.02021052332 37696.513469442056 12865.49415104482 12223.364422582554 15543.620169739257 11773.957672700431 12305.768751460337 9813.212884246832 13952.997538939459 8800.000837747684 4.0373882759330275 4.283694304634895 1.4619878325304432 1.3890185521517588 1.7663203056827854 1.3379496081632096 1.3983826795418732 1.1151377215957714 1.5855677512083803 1.0 13.103287945754564 -5.2637971527789995 24.87844959456123 1.3989250017586723 4.160541497326938 0.9650286325347783 0.2115698336073502 26.916162428108002 284014.2144204519 0.0532567692791949 0.11998835438306034 5.44757034725868e-06 5.2637971527789995 2.7616164955682656 KGLVGPELHDR ddPTM_PC-9_AZD4547_30min_R2 2 KGLVGPELHDR 11 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 90.434 0.0034678000000000005 13425500.0 103614.0 93831.0 134578.0 200918.0 166739.0 140217.0 118109.0 154689.0 128894.0 146949.0 False True 136561.09669491532 124160.03578478738 132793.4077882968 154599.45925215632 143590.16797464242 131449.20882407896 128620.4721925492 130785.36944959324 135707.0736976838 141804.3602377945 0.9630246662790436 0.8755727650164 0.9364550396448527 1.0902306458906164 1.0125934613988827 0.9269757897687294 0.9070276257857165 0.9222944148563325 0.9570021222909787 1.0 17.113542368063122 -5.531923061762591 24.99940801794795 0.9709211136859944 0.9159774787220932 0.14859638314797663 0.05406918980863741 384.05705435614567 1061568.8022564857 0.016301664194735214 0.028286250632002366 2.938170122787727e-06 5.531923061762591 -0.0549436349639012 KGLVGPELHDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGLVGPELHDR 11 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 88.338 0.0039212 3227100.0 54817.0 41916.0 53885.0 70758.0 78964.0 74548.0 61887.0 61779.0 65318.0 53265.0 False True 64096.43541489857 46077.14346680653 55169.82276000049 66793.65866053112 63491.57104781693 70638.57164574631 56024.615336920695 60157.366710261245 66273.15218048435 62921.52285449201 1.0186726656810832 0.7322954273271701 0.8768036795228626 1.061539130497422 1.0090596693701004 1.1226456137926004 0.8903887381505271 0.9560697831388639 1.053266818314984 1.0 15.941265967468288 -5.692696955638566 7.0503130581338755 1.0105474211378402 0.859509506741674 0.3378774999745441 0.08729325667277166 0.23298113557771916 19.55586241308949 0.02338084902028406 0.040556526087074246 2.029098100736675e-06 5.692696955638566 -0.1510379143961662 KGLVGPELHDR ddPTM_PC-9_Lapatinib_30min_R1 1 KGLVGPELHDR 11 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 81.92 0.0057618 4162300.0 89309.0 69287.0 74106.0 70249.0 74822.0 78700.0 71841.0 72214.0 79272.0 63605.0 False True 88035.43728273506 69126.57020848047 68013.29073743238 75415.34580379415 70421.11706571186 75334.18445866041 75560.57545928737 75569.32607016813 70343.55258883287 74599.03950166487 1.1801148898273728 0.9266415582594428 0.911718048808316 1.0109425846174742 0.9439949567197877 1.0098546169214302 1.0128893879069454 1.0130066898311956 0.9429552050366945 1.0 16.18686943476045 -4.7529622596952406 24.99786734622555 0.975575481162716 1.1801152728903535 0.7257869640157397 0.03788086202385995 178.07306280206438 525072.799630312 0.009861489495881923 0.1115542567008713 1.7661912965059525e-05 4.7529622596952406 0.20453979172763748 KGNAEGSS(ph)DEEGKLVIDEPAK ddPTM_PC-9_Lapatinib_30min_R1 1 KGNAEGSSDEEGKLVIDEPAK 21 2 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 KGNAEGS(0.198)S(0.802)DEEGKLVIDEPAK 58.01 0.0043227 8113100.0 15455.0 37499.0 29091.0 30854.0 39040.0 29667.0 35343.0 44300.0 21740.0 28436.0 True False 15234.608865900122 37412.17336943169 26699.250274507427 33123.10608592674 36743.743955593134 28398.211567154747 37172.88760537285 46358.33972510104 19291.412267650983 33351.12471141172 0.45679445589093765 1.121766467942546 0.8005502214853873 0.9931630903767703 1.1017242828701534 0.8514918706006265 1.1145917244779886 1.3900082868641204 0.5784336340852115 1.0 15.025447794279124 -4.753787964581138 24.995536808560146 1.0033349493534252 0.4567934768627793 0.3762724375752887 0.20746917819367502 286.7343531867957 936623.2131418828 0.049230834047545885 0.5125591462252371 1.7628365052962222e-05 4.753787964581138 -0.5465414724906459 KGNS(ph)PNSEPPTPK ddPTM_PC-9_AZD4547_30min_R2 4 KGNSPNSEPPTPK 13 1 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 KGNS(0.995)PNS(0.005)EPPTPK;KGNS(1)PNSEPPTPK;KGNS(0.977)PNS(0.023)EPPTPK;KGNS(1)PNSEPPTPK 94.454 0.0017254999999999998 105405700.0 229660.0 234015.0 273762.0 310339.0 319237.0 308850.0 247811.0 299892.0 249180.0 283366.0 True False 302687.10277524503 309655.772337256 270131.7370070869 238795.13823975416 274916.4529817314 289537.56067607284 269865.69892648194 253550.58223259257 262351.1460889475 273445.4425898979 1.1069378224350317 1.1324225022892953 0.9878816573009017 0.8732825677328592 1.0053795388868105 1.0588494653037945 0.9869087462950161 0.9272437669142549 0.9594277513061749 1.0 18.06089349189159 -5.292560562039896 6.129328876072057 0.9726911687385298 1.1200721490632939 0.6037061493300742 0.04695373808397735 0.117920560104474 14.834212383481798 0.013305134465807361 0.029336723467295805 5.098464949059127e-06 5.292560562039896 0.1473809803247641 KGNS(ph)PNSEPPTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 KGNSPNSEPPTPK 13 1 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 KGNS(0.894)PNS(0.106)EPPTPK;KGNS(0.987)PNS(0.013)EPPTPK;KGNS(1)PNSEPPTPK;KGNS(0.975)PNS(0.025)EPPTPK 96.135 0.004906300000000001 142062300.0 201523.0 174941.0 169205.0 238633.0 236243.0 212774.0 210598.0 203676.0 180937.0 173268.0 True False 235636.8636393194 192307.98633520884 173239.4889135359 225263.1666686243 189952.88003456514 201615.75687278016 190648.6328425162 198329.72081256058 183582.86132582618 204680.116811267 1.1512445239446352 0.9395538234548383 0.8463913916625222 1.1005620388439423 0.928047545574338 0.9850285411879433 0.9314467658737509 0.9689740454635266 0.8969257209048089 1.0 17.643011436245985 -4.758751162973161 24.99637171496651 0.9547262397801495 1.1512447859891957 0.45754747072845037 0.06403144289900062 65.348616024215 607525.0737723096 0.01531030889213986 0.10242343602888826 1.7428051597047168e-05 4.758751162973161 0.19651854620904619 KGNS(ph)PNSEPPTPK ddPTM_PC-9_Lapatinib_30min_R1 5 KGNSPNSEPPTPK 13 1 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 KGNS(0.72)PNS(0.279)EPPT(0.001)PK;KGNS(0.998)PNS(0.002)EPPTPK;KGNS(0.994)PNS(0.006)EPPTPK;KGNS(0.947)PNS(0.052)EPPT(0.001)PK;KGNS(0.76)PNS(0.239)EPPT(0.001)PK 106.76 0.0015911 190611900.0 238155.0 222464.0 248039.0 224904.1 232954.0 244537.0 212857.0 215928.0 232529.0 189297.8 True False 234758.8660277219 221948.89827614717 227646.190878229 241444.2977720841 219252.10372518565 234078.7225535891 223877.69394269996 225960.80316391934 206339.1353810771 222017.6725065369 1.057388195170859 0.9996902308288647 1.0253516682169812 1.0875003554727167 0.9875434745796201 1.0543247296977996 1.0083778080148476 1.0177604359728 0.9293815805361252 1.0 17.760314993457136 -8.100558488216148 5.568817895685522 0.965164923144492 1.0302034628255463 0.3995977900802741 0.03220261562320336 0.21776662290931417 9.662260860170845 0.021309763589104223 0.007826312381738733 7.933074116252351e-09 8.100558488216148 0.06503853968105433 KGNSPNS(ph)EPPTPK ddPTM_PC-9_AZD4547_30min_R2 1 KGNSPNSEPPTPK 13 1 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 KGNS(0.318)PNS(0.666)EPPT(0.016)PK 104.59 0.0013048 0.0 6884.4 7218.0 7748.1 9268.3 9952.4 9134.7 7288.7 9301.1 6725.1 7996.5 True False 9073.495995584344 9551.077344316864 7645.355131481396 7131.636628807569 8570.681050928886 8563.505764959424 7937.380179917141 7863.828713015243 7080.57505643624 7716.544968945169 1.1758495585913324 1.2377401262812144 0.9907743896069714 0.9242007475506806 1.1106889268994276 1.1097590695606394 1.028618405239743 1.0190867473283458 0.9175835927778097 1.0 12.913739319732755 -5.262185183806549 24.99972025458104 1.0176603375149689 1.2067948540021256 0.6068690032300779 0.06241684694849159 44.54220166331429 1493145.895831585 0.017343143218825734 0.03993808426286073 5.467827642036199e-06 5.262185183806549 0.18913451648715673 KGNSPNS(ph)EPPTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KGNSPNSEPPTPK 13 1 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 KGNS(0.323)PNS(0.67)EPPT(0.007)PK;KGNS(0.179)PNS(0.821)EPPTPK 101.3 0.0029943 36237700.0 105904.0 103016.0 88041.0 101845.0 135246.0 127931.0 131478.0 131630.0 113669.0 103628.0 True False 123831.455500655 113242.74767097372 90140.23133735167 96138.9548359448 108745.51717153467 121222.07315034582 119023.45202171165 128174.85197351356 115331.19408437934 122414.9360812036 1.0115714590457472 0.9250729632849252 0.7363499440751037 0.7853531432812356 0.88833536701272 0.9902555769006284 0.9722951776305939 1.0470523947215815 0.9421333521578994 1.0 16.901420069196625 -6.702026186343464 4.07106501509769 0.9929895761767694 0.8574869219250849 0.40315272545257197 0.0736994582829224 0.23353452857162918 7.800880365709765 0.027747266362921994 0.02697549210210762 1.9859751668242756e-07 6.702026186343464 -0.1355026542516845 KGNSPNS(ph)EPPTPK ddPTM_PC-9_Lapatinib_30min_R1 1 KGNSPNSEPPTPK 13 1 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 KGNS(0.099)PNS(0.901)EPPTPK 136.3 8.0369e-05 9688600.0 49854.0 44916.0 45808.0 42384.0 45456.0 40576.0 39102.0 40371.0 47952.0 33670.0 True False 49143.07281789612 44811.99976163083 42041.84306399353 45501.0607488792 42782.36744993446 38840.65906727582 41126.510232444605 42246.784041581326 42551.14080305428 39489.814637545125 1.2444493160819527 1.1347736162586495 1.0646249786146642 1.1522226975869079 1.0833772668372803 0.9835614429637732 1.0414460186739742 1.0698146960004973 1.0775219178314042 1.0 15.269192975453002 -1.522878745280368 0.485256739282506 1.0420471376439089 6.6091015864739955 0.6866861058954442 0.04057127805139293 63.61946222885349 0.7033497208746805 0.024594873588629034 358.2725103047032 0.029999999999997896 1.522878745280368 5.567054448830087 KGPAAPPPT(ph)PVKPPR ddPTM_PC-9_AZD4547_30min_R2 2 KGPAAPPPTPVKPPR 15 2 E9PIE3;Q969G5 E9PIE3 PRKCDBP Protein kinase C delta-binding protein 1 KGPAAPPPT(1)PVKPPR;KGPAAPPPT(1)PVKPPR 69.111 0.012473 68819000.0 298040.0 241472.0 337390.0 434120.0 419340.0 377080.0 316880.0 483020.0 344080.0 431960.0 True False 392810.52038288955 319523.10175767285 332915.9881532903 334040.3410871404 361121.87933528813 353501.1279900714 345081.70612209936 408380.357695393 362267.36634675815 416837.2118783919 0.9423595331442916 0.7665416921819602 0.7986714685406139 0.8013688115364165 0.8663379109268244 0.8480555908074777 0.8278572456788563 0.9797118540715455 0.8690859549565504 1.0 18.669124550028393 -8.118615466017278 0.6423697185917543 0.9920714734742444 0.8222524148458251 0.4333164499608336 0.056807022328799965 0.6181515020412982 0.5704404185181641 0.05354063777788499 0.02501170552926109 7.609997848428996e-09 8.118615466017278 -0.16981905862841928 KGPAAPPPT(ph)PVKPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KGPAAPPPTPVKPPR 15 2 E9PIE3;Q969G5 E9PIE3 PRKCDBP Protein kinase C delta-binding protein 1 KGPAAPPPT(1)PVKPPR;KGPAAPPPT(1)PVKPPR;KGPAAPPPT(1)PVKPPR 69.289 0.012302 37208800.0 171054.0 139193.0 149678.0 169196.0 170512.0 148325.0 155205.0 153786.0 127290.0 104153.0 True False 200010.06372950075 153011.16114551018 153246.89117697615 159716.49666083342 137101.3976306336 140546.57588876048 140502.85881310765 149749.28044973608 129151.37544097917 123035.11442530551 1.6256339880183284 1.2436381423321479 1.2455540996795038 1.2981375065717287 1.1143273875188513 1.1423289728729122 1.1419736509320417 1.2171263557498353 1.0497115075175294 1.0 16.908710596321853 -1.5228787452803376 0.6224191466412332 1.128399518206011 34.483733427466326 0.7775106357473229 0.077659968819132 89.69493931804182 0.6414847127693114 0.03301289090430523 4094.5541446557736 0.029999999999999995 1.5228787452803376 33.35533390926032 KGPAS(ph)PTRPAAPRPAEAPLLDL ddPTM_PC-9_Lapatinib_30min_R1 1 KGPASPTRPAAPRPAEAPLLDL 22 3 A0A0D9SFE4 A0A0D9SFE4 DNM1 1 KGPAS(0.821)PT(0.179)RPAAPRPAEAPLLDL 49.768 0.033147 37742000.0 81323.0 65869.0 65817.0 58958.0 64337.0 50669.0 46769.0 52577.0 63407.0 43463.0 True False 80163.31910718826 65716.4843774794 60405.78032096717 63293.967998122396 60552.82415140873 48502.00498520798 49190.46997752546 55019.91936177507 56265.43595468932 50975.52163919286 1.5725845764676623 1.2891772808647994 1.1849958250260217 1.2416541501256246 1.1878804219014072 0.9514763836750402 0.9649821795978454 1.0793399967774464 1.1037736181090743 1.0 15.637517013154266 -1.522878745281005 0.41928010060917575 1.0208108493738706 10.854637874494168 0.8338849263124781 0.07195761975129986 33.055575071962956 0.4241272038524617 0.054154654594816186 272.49432902505987 0.02999999999995389 1.522878745281005 9.833827025120298 KGPDEAEESQYDS(ph)GIESLR ddPTM_PC-9_Lapatinib_30min_R1 1 KGPDEAEESQYDSGIESLR 19 1 H3BNC2;Q7LC14;O00221 H3BNC2 NFKBIE NF-kappa-B inhibitor epsilon 1 KGPDEAEES(0.001)QY(0.002)DS(0.995)GIES(0.002)LR 84.948 0.00060692 3448500.0 13409.0 11411.0 15340.0 8190.3 13088.0 14460.0 14702.0 14027.0 13140.0 10175.0 True False 13217.785201090559 11384.578530589744 14078.804414112392 8792.641984039865 12318.189571998033 13841.57950790636 15463.197622561524 14678.745628081086 11660.034829665767 11933.735192664722 1.1075983326004335 0.9539828349457153 1.1797483509409672 0.7367887624525484 1.0322157625526684 1.159869838272792 1.2957550484333058 1.2300210613943932 0.9770649877360116 1.0 13.542758048778964 -6.697155469871991 5.022874175456891 1.1572557846790492 0.9918099461657788 0.1688284938839517 0.14049689584405484 0.30701559060630146 15.029357979192104 0.047311509212424954 0.046542742635146295 2.0083737210394483e-07 6.697155469871991 -0.16544583851327044 KGPEADSEWR ddPTM_PC-9_Lapatinib_30min_R1 1 KGPEADSEWR 10 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 64.73 0.032053 5100500.0 45577.0 40246.0 45874.0 44610.0 40539.0 45648.0 36329.0 32034.0 42454.0 37538.0 False True 44927.06362220182 40152.81285970686 42102.41679876089 47890.76821459753 38154.57572274053 43695.741450685295 38209.937860837796 33522.416585866515 37672.383459560915 44026.393283759055 1.0204575090364039 0.912016857726996 0.9562994753488494 1.0877740519404302 0.8666296027663799 0.9924896906511819 0.8678870788839544 0.761416370625859 0.855677257429532 1.0 15.426081040659046 -7.330680712324555 5.478903266078784 0.8494201760005083 0.9694729442652762 0.2701062531848627 0.07861338004580176 0.25579933744034106 14.607266284221817 0.03233173109994706 0.021645470218121483 4.6700258838926244e-08 7.330680712324555 0.12005276826476785 KGPGQPS(ph)SPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGPGQPSSPQR 11 1 O95400 O95400 CD2BP2 CD2 antigen cytoplasmic tail-binding protein 2 1 KGPGQPS(0.5)S(0.5)PQR 73.273 0.029352999999999997 0.0 6167.3 9272.8 8820.6 6386.7 7251.8 5309.0 9246.7 6396.4 7925.2 5927.0 True False 7211.302080272614 10193.342302199724 9030.916556311784 6028.873904960772 5830.861847481874 5030.586694039644 8370.785635689319 6228.501277546011 8041.09105699463 7001.518181893818 1.0299626299509306 1.4558760025161515 1.2898511896557041 0.8610809467797513 0.8327996437345112 0.718499411606032 1.1955672210259307 0.8895929590889505 1.1484782083104754 1.0 12.77345206900641 -5.754345481807034 24.985243563820884 0.9406047611239416 1.2782946556927834 0.4198263377398851 0.16581963882924894 145.95178109903523 514047.07384348416 0.04522258057265944 0.07625256814880908 1.7605749496097951e-06 5.754345481807034 0.3376898945688418 KGPGQPSS(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 1 KGPGQPSSPQR 11 1 O95400 O95400 CD2BP2 CD2 antigen cytoplasmic tail-binding protein 2 1 KGPGQPS(0.131)S(0.869)PQR 89.44 0.013634 24926000.0 3975.7 9812.0 7623.0 10379.0 11386.0 8223.4 9375.4 10701.0 8753.7 7587.7 True False 3919.0057889459104 9789.280916847478 6996.2663656309505 11142.30628332903 10716.297865737286 7871.704351681683 9860.812337815483 11198.207525921136 7767.7661254524555 8899.223835025277 0.44037613409852827 1.1000151359626602 0.7861659056259797 1.25205371725515 1.2041834281727388 0.8845383032956743 1.1080530752587228 1.2583353035629459 0.872858832348989 1.0 13.119463798472575 -4.759139537519612 24.99688022740479 1.0591231801611083 0.4403753302955351 0.5781026405085495 0.1565860732575781 43.6001510224063 473781.2633518593 0.038322989531506244 0.2491019327429422 1.741247325941991e-05 4.759139537519612 -0.6187478498655732 KGPGQPSS(ph)PQRLDR ddPTM_PC-9_AZD4547_30min_R2 1 KGPGQPSSPQRLDR 14 2 O95400 O95400 CD2BP2 CD2 antigen cytoplasmic tail-binding protein 2 1 KGPGQPS(0.149)S(0.851)PQRLDR 85.28 0.019556999999999998 42379000.0 15208.0 8977.3 16904.0 18222.0 18869.0 14020.0 14400.0 16758.0 13355.0 13472.0 True False 20043.827653949043 11879.036664330253 16679.84191512261 14021.199427093583 16249.365052648327 13143.327183676653 15681.572103503631 14168.436160530411 14060.918035227132 13000.349380557653 1.5417914601529932 0.913747493747795 1.2830302807144347 1.0785248162686025 1.2499175658270891 1.010997996971745 1.2062423589135085 1.089850414460373 1.0815800117076535 1.0 13.66626277532816 -4.743743067425272 24.999591381551927 1.114382395713917 1.5417927740816153 0.5858982129092158 0.11056211933912846 769.6452016233994 1087221.1446987905 0.025036595068689882 0.7739892333496029 1.8040847381837764e-05 4.743743067425272 0.42741037836769835 KGPGQPSS(ph)PQRLDR ddPTM_PC-9_Lapatinib_30min_R1 1 KGPGQPSSPQRLDR 14 2 O95400 O95400 CD2BP2 CD2 antigen cytoplasmic tail-binding protein 2 1 KGPGQPS(0.188)S(0.812)PQRLDR 103.13 0.0036253 152190000.0 34145.0 17288.0 19981.0 18942.0 20637.0 19751.0 17588.0 14348.0 21004.0 16329.0 True False 33658.08603857388 17247.970698171564 18338.239308890483 20335.057868659645 19423.172233903057 18906.295771829773 18498.62058125506 15014.660459949202 18638.30833807457 19151.44589297517 1.7574697089017077 0.9006093218527271 0.9575381102487424 1.061802747547047 1.0141882937949638 0.9871993935854566 0.9659124791220297 0.7839961820040251 0.9732063282444475 1.0 14.225165696184243 -4.758870538710754 24.999878312562842 0.9594998322154843 1.7574707618847845 0.9190257436396118 0.07096956640495378 18.997482294762325 184845.31266154596 0.01898013784561668 0.12583561264776189 1.742326175814175e-05 4.758870538710754 0.7979709296693002 KGPQT(ph)KKS(ph)S(ph)AT(ph)S(ph)PPICPDPSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGPQTKKSSATSPPICPDPSAK 22 3 E9PAV3 E9PAV3 NACA Nascent polypeptide-associated complex subunit alpha, muscle-specific form 5 KGPQT(1)KKS(1)S(1)AT(0.999)S(0.999)PPICPDPS(0.003)AK 44.382 0.041756 0.0 4857.9 6213.8 6545.1 5523.6 5361.6 5245.6 7558.0 6258.9 4808.0 5444.1 True False 5680.246522101457 6830.664998426441 6701.160006429972 5214.130599752819 4311.0329685676425 4970.511501648964 6842.051524818562 6094.610506852715 4878.307904157649 6431.072234528109 0.8832503064737003 1.0621347030986432 1.0419973158522111 0.8107715804774217 0.6703443549307251 0.7728900127979489 1.063905251768737 0.9476818615301896 0.7585528083429471 1.0 12.650843578743062 -3.4471019670887992 9.483975669102234 0.9001168388140487 0.7538276323084172 0.0 0.13517953581663256 0.0 0.0 0.03350033781677041 0.0 0.000357188964659642 3.4471019670887992 -0.14628920650563149 KGPS(ph)STGASGQAK ddPTM_PC-9_Lapatinib_30min_R1 1 KGPSSTGASGQAK 13 1 Q9NWH9;H7BXE3 Q9NWH9 SLTM SAFB-like transcription modulator 1 KGPS(0.616)S(0.331)T(0.029)GAS(0.025)GQAK 87.863 0.012019 0.0 7715.8 12123.0 8141.9 7331.9 9336.8 7539.9 10514.0 8194.1 11139.0 6833.1 True False 7605.771277095572 12094.929938334906 7472.504410642878 7871.1123845014 8787.627780855077 7217.436053365364 11058.363474602897 8574.827800032743 9884.408521129904 8014.192230466567 0.9490377892586166 1.5091888977101275 0.9324089310255846 0.9821466915378898 1.0965082354087086 0.9005818485271325 1.3798475450293892 1.069955343401282 1.2333630435708252 1.0 12.968341399698422 -10.369605114423813 15.156722234812417 1.000009771440216 1.1185221314426113 0.03247998264129881 0.1914164483284751 0.0 0.0 0.17901411398640385 0.04341730002601782 4.26967565879279e-11 10.369605114423813 0.11851236000239518 KGPS(ph)TPYTK ddPTM_PC-9_Lapatinib_30min_R1 1 KGPSTPYTK 9 1 F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 F8VXC8 SMARCC2 SWI/SNF complex subunit SMARCC2 1 KGPS(0.903)T(0.041)PYT(0.056)K 84.18799999999999 0.019685 20239000.0 76481.0 62863.0 75727.0 64218.0 61799.0 62060.0 59336.0 47110.0 70093.0 50399.0 True False 75390.3669151025 62717.444585791236 69501.01837467325 68940.80594496812 58164.10432150874 59405.838468925875 62408.12774672224 49298.90258351039 62198.38822798803 59110.399997553795 1.2754162874591006 1.0610221651077765 1.1757832526518084 1.1663058606915389 0.9839910459735645 1.0049980793800128 1.0557892984873205 0.8340140243603589 1.0522410308602552 1.0 15.851124362827049 -6.262167527743933 24.035688925107518 0.9843950836282699 1.1623134462407771 0.5823902510272048 0.0749882535626584 27.656203871349962 912917.8259957273 0.02198938962431231 0.026431288675123777 5.468049938827146e-07 6.262167527743933 0.17791836261250726 KGPSS(ph)TGASGQAK ddPTM_PC-9_AZD4547_30min_R2 1 KGPSSTGASGQAK 13 1 Q9NWH9;H7BXE3 Q9NWH9 SLTM SAFB-like transcription modulator 1 KGPS(0.11)S(0.39)T(0.39)GAS(0.11)GQAK 101.62 0.0028725 3613200.0 17701.0 12468.0 17700.0 13143.0 16076.0 20387.0 16123.0 12356.0 18515.0 21878.0 True False 23329.54979632773 16498.037174971283 17465.28643502545 10113.084407325821 13844.124891959003 19112.197667162334 17557.91576561034 10446.664112633585 19493.665100878337 21112.057879144922 1.1050343803468494 0.7814509257891199 0.8272659413404766 0.47901935781048643 0.6557449288557803 0.9052740275992657 0.8316534497072661 0.4948197931454655 0.9233427272920998 1.0 14.365779590510092 -4.630337497409364 2.2661869885504666 0.7407414071560526 1.3154572844151236 0.26016550666899174 0.16731878390172192 1.4675449098511095 6.012902922050676 0.043208288258328 1.97438338956986 2.3424077840873834e-05 4.630337497409364 0.5747158772590709 KGPSS(ph)TGASGQAK ddPTM_PC-9_Lapatinib_30min_R1 1 KGPSSTGASGQAK 13 1 Q9NWH9;H7BXE3 Q9NWH9 SLTM SAFB-like transcription modulator 1 KGPS(0.205)S(0.737)T(0.058)GASGQAK 114.21 0.00045288 1768100.0 5248.4 9041.2 6670.0 6480.0 8306.6 5831.5 8004.0 10701.0 11359.0 7911.3 True False 5173.556853561319 9020.26565688967 6121.618346944567 6956.560816646316 7818.022119403944 5582.10033889045 8418.40795612722 11198.207525921136 10079.629804427208 9278.757663855378 0.5575699938489046 0.9721415283888011 0.6597454711842317 0.7497297664907249 0.8425720772790944 0.6015999707196852 0.9072774891966864 1.2068649631343227 1.086312432071759 1.0 13.17971593999594 -7.54439806382595 5.156815889228097 1.1054471146460372 0.7442515589504035 0.649017890841311 0.1209380765185166 0.10633659983701219 7.9468834863254845 0.05390729809947673 0.03149973520281074 2.8549725449263525e-08 7.54439806382595 -0.36119555569563366 KGPSTPY(ph)TK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGPSTPYTK 9 1 F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 F8VXC8 SMARCC2 SWI/SNF complex subunit SMARCC2 1 KGPS(0.114)T(0.114)PY(0.658)T(0.114)K 69.423 0.037216 24147000.0 80807.0 72308.0 100850.0 97059.0 109590.0 104400.0 84692.0 102050.0 87551.0 73288.0 True False 94486.02908899992 79486.26037307575 103254.64647575494 91621.09889952354 88116.62619839748 98925.08021430369 76669.36064301866 99371.29563091275 88831.26774478097 86574.53425251128 1.0913836257370237 0.9181251861111812 1.1926676518361958 1.0582915598747893 1.017812304267077 1.14265795442537 0.8855879076334124 1.1478120730176526 1.0260669434927308 1.0 16.40165510068521 KGQAVDYEGSR ddPTM_PC-9_AZD4547_30min_R2 1 KGQAVDYEGSR 11 1 A0A499FI48;P13667 A0A499FI48 PDIA4 Protein disulfide-isomerase A4 0 80.87100000000001 0.009926299999999999 5168400.0 8623.4 6311.2 9415.4 14477.0 13145.0 10206.0 7080.1 10694.0 7682.9 11847.0 False True 11365.46182213731 8351.171977757363 9290.54564408693 11139.551317420372 11320.043649216286 9567.817206605137 7710.215184028891 9041.488023672999 8089.002409048781 11432.240135946162 0.9941587726451894 0.7304930510949418 0.8126618697305749 0.9743979469425686 0.9901859578354116 0.8369153457965988 0.6744273294072801 0.7908763213645268 0.7075605754304175 1.0 13.48082050544327 -7.002453191326481 24.898676033834924 0.7729151136860467 0.8925173529042902 0.1598099224521743 0.11183226222456417 154.1857593016111 1564925.7001724227 0.03974593377543716 0.03446278192054103 9.943672420273549e-08 7.002453191326481 0.11960223921824353 KGQAVDYEGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGQAVDYEGSR 11 1 A0A499FI48;P13667 A0A499FI48 PDIA4 Protein disulfide-isomerase A4 0 59.265 0.043386 2065800.0 11845.0 11140.0 12843.0 17588.0 16329.0 15265.0 14996.0 13499.0 11863.0 9876.0 False True 13850.124550586015 12245.905578304817 13149.225827348724 16602.601381065346 13129.449668707293 14464.476527503324 13575.470318361902 13144.665553372774 12036.47393240893 11666.440621627018 1.1871765347959622 1.0496693872168343 1.127098337343178 1.423107691499991 1.1254032051873797 1.239836295972686 1.1636342873246157 1.126707449143096 1.031717755464846 1.0 13.51007684798158 -8.150414075761873 1.7269342132535364 0.9997181539187457 1.1902901956177345 0.35798951073955354 0.0921929843694556 0.43039470947026864 2.3017506011442714 0.08790619559263653 0.027150629999376154 7.072711189238589e-09 8.150414075761873 0.19057204169898878 KGQAVDYEGSR ddPTM_PC-9_Lapatinib_30min_R1 1 KGQAVDYEGSR 11 1 A0A499FI48;P13667 A0A499FI48 PDIA4 Protein disulfide-isomerase A4 0 67.214 0.025477 3930900.0 13289.0 13646.0 15971.0 14157.0 14086.0 16218.0 13989.0 12998.0 18614.0 11015.0 False True 13099.496423095863 13614.403525407743 14657.926029842843 15198.153006367573 13257.489174141523 15524.393946004522 14713.281971297303 13601.934531531906 16517.495305890297 12918.928073435092 1.0139770380819806 1.0538338357500991 1.1346085330394875 1.1764252359001208 1.0262065938274405 1.2016781777682464 1.1388934041324916 1.0528686632679118 1.2785499858811706 1.0 13.65719874932624 -5.115623840966185 3.2520038963433078 1.129455999134025 1.0195108042200218 0.183315651793015 0.07949241229799585 0.39303391579043734 7.54615307019681 0.019445966231976326 0.06959327967632926 7.662600066223713e-06 5.115623840966185 -0.10994519491400312 KGQGGAGAGDDEEED ddPTM_PC-9_AZD4547_30min_R2 1 KGQGGAGAGDDEEED 15 1 P46781 P46781 RPS9 40S ribosomal protein S9 0 76.165 0.032133 4281500.0 7023.2 7586.2 7045.3 9089.5 8620.9 7671.2 8599.6 8095.9 6758.3 7828.2 False True 9256.431508364996 10038.290793773433 6951.87471868276 6994.056206375107 7424.036842565896 7191.518651313866 9364.94774036735 6844.86468027438 7115.529940657094 7554.137100718634 1.225345977303539 1.3288467842102678 0.9202738348528808 0.9258577271134983 0.9827776149124482 0.9519973698425103 1.2397111166378554 0.906108082102881 0.9419381520068235 1.0 12.883051252280783 -5.2597499591687455 24.997532103555695 0.9861586973052349 1.2770964005489835 0.6119988144543249 0.09346424293765124 96.102772512904 1421957.0392254698 0.024788638353112732 0.058986440034967044 5.4985735777761316e-06 5.2597499591687455 0.2909377032437487 KGQGGAGAGDDEEED ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGQGGAGAGDDEEED 15 1 P46781 P46781 RPS9 40S ribosomal protein S9 0 76.165 0.032133 18823000.0 109200.0 113080.0 90215.0 124990.0 136170.0 112700.0 130990.0 127920.0 119380.0 92004.0 False True 127685.40320168772 124305.83508031513 92366.06774229262 117987.21552304763 109488.46600452396 106789.81360298887 118581.67891452553 124562.23554244377 121125.70665522886 108683.59689673678 1.1748360088137777 1.1437405333430533 0.8498620802001254 1.0856027854428711 1.0074056171379009 0.9825752611449983 1.0910724552776183 1.1460996792440878 1.1144801066007566 1.0 16.729774692065675 -7.490970264563842 21.853250147508668 1.101891136569879 1.037180181695198 0.05206219306989246 0.09170602932839178 354.9560521650573 243100.992608844 0.039412846606834646 0.02651998981931867 3.228715179016893e-08 7.490970264563842 -0.06471095487468093 KGQGGAGAGDDEEED ddPTM_PC-9_Lapatinib_30min_R1 2 KGQGGAGAGDDEEED 15 1 P46781 P46781 RPS9 40S ribosomal protein S9 0 ; 103.43 0.0029069000000000005 60053000.0 341850.0 338430.0 317470.0 294890.0 338790.0 310280.0 291830.0 301300.0 319540.0 281530.0 False True 336975.1563123874 337646.3861280766 291368.8420696389 316577.19432420295 318863.0382867678 297010.04769800697 306939.5294648435 315299.4979497285 283550.0402946274 330192.08538485586 1.0205428028949437 1.0225756493664357 0.8824222474322287 0.9587667552819019 0.9656895255836205 0.8995068653805753 0.9295786999470012 0.9548972004650891 0.8587426920428309 1.0 18.33294601409178 -5.241071724828742 24.50574763305414 0.9306161084872054 1.0215592633288741 0.4512050999094074 0.039856824181754 533.0582751617543 641356.3348622067 0.00957459009023065 0.02526105685073663 5.740216532551676e-06 5.241071724828742 0.0909431548416687 KGQMVILFQNEGTS(ph)SIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGQMVILFQNEGTSSIR 17 1 A0A0C4DG31;Q9GZR2-2 A0A0C4DG31 REXO4 RNA exonuclease 4 1 KGQMVILFQNEGT(0.048)S(0.919)S(0.034)IR 65.374 0.020749 3768000.0 15168.0 17005.0 15806.0 17295.0 20592.0 18470.0 19003.0 16450.0 18435.0 19244.0 True False 17735.64281834432 18693.144017870167 16182.874984588803 16326.017221146538 16557.14542090884 17501.40068542328 17202.89827019412 16018.204930215727 18704.576999406447 22732.784864579815 0.7801790640256491 0.8222989013104217 0.7118738456810677 0.7181705769179328 0.7283377518214541 0.7698749092854167 0.756743987710812 0.7046301201386838 0.8228018305205641 1.0 14.47248681092102 -8.608549887942196 4.453304003754472 0.9999657165374125 0.7498532942362365 0.8327709004764388 0.034080882792264545 0.18968178455464133 8.90526575674681 0.034920335352826584 0.009111402634074487 2.462918903456126e-09 8.608549887942196 -0.25011242230117603 KGRS(ph)PDELPSAGGDGGK ddPTM_PC-9_AZD4547_30min_R2 4 KGRSPDELPSAGGDGGK 17 2 B4E2I7;A0A2R8Y5N1;A0A140T8Z0;A0A0G2JH68;O60610-2;O60610-3;O60610 B4E2I7 DIAPH1 Protein diaphanous homolog 1 1 KGRS(1)PDELPSAGGDGGK;KGRS(0.996)PDELPS(0.004)AGGDGGK;KGRS(1)PDELPSAGGDGGK;KGRS(1)PDELPSAGGDGGK 82.34899999999999 0.015276 12112200.0 79429.0 63821.6 90181.0 137079.0 115765.0 96120.0 84533.0 94830.0 78322.0 98466.0 True False 104685.76977416614 84450.68410058918 88985.14101678134 105477.55439943812 99693.02799935524 90109.60120506409 92056.27323788017 80176.20247661418 82461.94102246795 95018.73531071763 1.101738193334574 0.8887792899413971 0.9365010039945698 1.110071124968349 1.049193379319903 0.9483350931834617 0.9688223373722034 0.8437936183262451 0.8678492799637026 1.0 16.535924384308117 -7.340966388838164 2.0641231911516806 0.8956965140190104 1.0076724946236213 0.2548068842415707 0.07656958789857582 0.4548597972617086 3.781805420871541 0.04144957224787665 0.024921602792964348 4.5607221118154446e-08 7.340966388838164 0.11197598060461089 KGRS(ph)PDELPSAGGDGGK ddPTM_PC-9_Lapatinib_30min_R1 2 KGRSPDELPSAGGDGGK 17 2 B4E2I7;A0A2R8Y5N1;A0A140T8Z0;A0A0G2JH68;O60610-2;O60610-3;O60610 B4E2I7 DIAPH1 Protein diaphanous homolog 1 1 KGRS(1)PDELPSAGGDGGK;KGRS(0.988)PDELPS(0.012)AGGDGGK 107.13 0.0017170999999999998 10979900.0 86684.0 53349.0 64629.0 57004.0 64809.0 55374.0 47072.0 47680.0 60175.0 46602.7 True False 85447.87026410137 53225.47366825279 59315.453095154495 61196.26431976951 60997.06203939642 53005.78310309864 49509.15783493507 49895.386864397675 53397.45782915812 54657.914600805576 1.5633210832899576 0.9737926164396387 1.0852125173154754 1.1196231097859626 1.1159785821484198 0.969773243092546 0.9058003437658666 0.9128666402443076 0.9769391719231659 1.0 15.738142796372337 -4.759227084160734 24.999976334988528 1.0090378832232685 1.5633217971605693 0.8395936167863819 0.0729868937526979 25.851058490531997 292060.9531196671 0.021214870601358925 0.13715462168973386 1.7408963544298152e-05 4.759227084160734 0.5542839139373008 KGS(ph)DALRPPVPQGEDEVPK ddPTM_PC-9_Lapatinib_30min_R1 1 KGSDALRPPVPQGEDEVPK 19 2 Q8N3D4;E9PIH6 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 KGS(1)DALRPPVPQGEDEVPK 47.0 0.026282999999999997 5620500.0 58547.0 64309.0 38512.0 54201.0 62634.0 57908.0 56862.0 57876.0 61862.0 48456.0 True False 57712.10904379515 64160.0964616332 35345.69202061907 58187.122349235586 58949.99126318188 55431.409830141194 59806.036132097186 60565.130246725654 54894.45012426055 56831.55503643851 1.0154941037033398 1.128951977831609 0.6219377949091237 1.023852370605167 1.0372757040588647 0.9753632430891678 1.05233854843056 1.0656954610496456 0.9659149760914345 1.0 15.794404570790622 KGS(ph)FGLHAQPEFLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGSFGLHAQPEFLR 14 1 Q9BZ71;Q9BZ71-3;Q9BZ71-2 Q9BZ71 PITPNM3 Membrane-associated phosphatidylinositol transfer protein 3 1 KGS(1)FGLHAQPEFLR 48.31399999999999 0.04218 4520700.0 44854.0 35498.0 31079.0 38997.0 24970.0 38668.0 35049.0 25425.0 33326.0 38192.0 True False 52446.89629311822 39022.00684189089 31820.041227763864 36812.12451997985 20077.307748644806 36640.18200887642 31728.90498721432 24757.62069001428 33813.32970340221 45115.90727229436 1.1624923328390164 0.8649278979668059 0.7052953858539497 0.8159455665559926 0.44501615865706556 0.8121344382533813 0.7032753391329672 0.5487559086552586 0.7494768862637269 1.0 15.461348577920575 -4.626047652579135 1.4597933667884337 0.6974388789036927 1.494308111324167 0.45831282907103355 0.14390886737756114 1.3845507508927317 2.0666811035367623 0.038648383269991565 1.790766243582118 2.365660113274426e-05 4.626047652579135 0.7968692324204742 KGS(ph)FSALVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGSFSALVGR 10 1 A0A087WWN2;Q13619 A0A087WWN2 CUL4A Cullin-4A 1 KGS(0.974)FS(0.026)ALVGR 79.283 0.028260000000000004 24182000.0 80861.0 75522.0 59567.0 53730.0 66540.0 45750.0 39479.0 69372.0 33673.0 33992.0 True False 94549.17022245114 83019.3250524897 60987.303189105456 50719.6822950103 53501.964661386715 43350.78946172794 35739.26331679175 67551.05850570982 34165.403921942685 40154.48051947608 2.354635622208886 2.0674984205616345 1.5188168891769092 1.2631138951084127 1.3324033574643488 1.0796003061402215 0.890044220580993 1.6822794774532226 0.8508491077445637 1.0 15.293273355152085 -5.170741398201079 1.1217737636521632 1.1485574957719042 2.5925610752559995 0.7846496150278908 0.22246337964714707 0.4146470668176329 0.6722382974201534 0.07060156885849977 0.6050719403132271 6.749297968030045e-06 5.170741398201079 1.4440035794840953 up KGS(ph)GDYMPMSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGSGDYMPMSPK 12 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 KGS(0.974)GDY(0.021)MPMS(0.005)PK 46.324 0.042851 14624000.0 75796.0 87838.0 68426.0 77604.0 79796.0 59305.0 50118.0 60669.0 54459.0 39695.0 True False 88626.76576076123 96557.97613888147 70057.53534705014 73256.09947556256 64160.546620378904 56194.941399514224 45370.46021710197 59076.50303411903 55255.35984869414 46891.3892745529 1.8900435054684412 2.0591835224485813 1.4940383816921603 1.5622505668715023 1.3682799254403337 1.198406408274412 0.9675648539959913 1.2598582372601779 1.1783690076907194 1.0 15.517035402686162 -5.697336244040845 0.6954899426010496 1.098638935762033 2.123800669200894 0.8667304350856557 0.12472014925976307 0.3978953630371952 0.3135178968699222 0.06564455220036165 0.27099882526050173 2.007537913646397e-06 5.697336244040845 1.025161733438861 KGS(ph)GDYMPMSPK ddPTM_PC-9_Lapatinib_30min_R1 1 KGSGDYMPMSPK 12 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 KGS(0.995)GDYMPMS(0.005)PK 67.902 0.016405 5965500.0 113020.0 89837.0 99875.0 96951.0 74429.0 61962.0 52808.0 54646.0 61725.0 48704.0 True False 111408.31407467024 89628.98794606904 91663.66302864911 104081.09995905514 70051.23255304419 59312.02970047674 55542.139848471576 57185.052655030944 54772.880506934554 57122.421505999315 1.950342985074075 1.569068425025639 1.6046879773649316 1.8220708649076434 1.2263351361196586 1.0383318517799085 0.9723351773985672 1.0010964372199287 0.958868322856061 1.0 15.801769518241539 -6.441518446680065 2.964926009912343 0.9950707441151238 1.716455647774297 0.916362882965559 0.1056934206839025 0.07249381986646383 1.2407571900786811 0.03569605271280268 0.03998246990729868 3.6181082247308066e-07 6.441518446680065 0.7213849036591732 KGS(ph)ITEYTAAEEK ddPTM_PC-9_AZD4547_30min_R2 1 KGSITEYTAAEEK 13 1 J3KN59;Q12982;Q12982-2 J3KN59 BNIP2 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 1 KGS(0.928)IT(0.072)EYTAAEEK 133.23 6.824600000000001e-05 22122000.0 25417.0 34034.0 23861.0 25339.0 22931.0 34191.0 28299.0 32069.0 30760.0 27334.0 True False 33499.077293557515 45034.824928855705 23544.587549499556 19497.48503364748 19747.42646787209 32053.031364984923 30817.556177572875 27113.47292230871 32385.91080221538 26377.044979822087 1.2700087261171082 1.7073491349507288 0.8926165750375259 0.739183826261155 0.7486595440459111 1.2151865908218624 1.1683475613416017 1.0279192738629355 1.2278066336464133 1.0 14.686995328075593 -5.269579108627507 24.997842385015463 0.998516305905511 1.4886789379924565 0.5083092605537041 0.19124835984899322 452.2261563424728 1388830.1525664798 0.053682273309983125 0.11487242267790303 5.37552506678138e-06 5.269579108627507 0.49016263208694555 KGS(ph)ITEYTAAEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGSITEYTAAEEK 13 1 J3KN59;Q12982;Q12982-2 J3KN59 BNIP2 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 1 KGS(0.979)IT(0.021)EYTAAEEK 83.292 0.014038 23595000.0 38806.0 57555.0 46561.0 49431.0 50226.0 34797.0 48182.0 37995.0 39694.0 31276.0 True False 45375.08934656315 63268.68003225618 47671.19082357581 46661.54132746423 40384.57585035778 32972.18406338243 43617.85215252821 36997.67150903016 40274.449656329816 36946.09121932021 1.228143163432541 1.7124593683450635 1.2902905084218252 1.2629628679924745 1.0930676160199455 0.8924403901796327 1.1805809684603155 1.0013960959876311 1.0900868894966922 1.0 15.173134119379716 -5.931570729426111 1.6959891988032012 1.0398768467383803 1.4644167678475357 0.6080294745168231 0.135335668368837 0.2253872766243368 1.316120554026678 0.0423636062969561 0.07544934954229801 1.1706559331578327e-06 5.931570729426111 0.4245399211091554 KGS(ph)ITEYTAAEEK ddPTM_PC-9_Lapatinib_30min_R1 2 KGSITEYTAAEEK 13 1 J3KN59;Q12982;Q12982-2 J3KN59 BNIP2 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 1 KGS(0.993)IT(0.007)EYTAAEEK;KGS(0.744)IT(0.249)EY(0.005)T(0.002)AAEEK 85.976 0.011493999999999999 84706000.0 463074.0 636686.0 488849.0 482046.0 624675.0 522312.0 595808.0 598587.0 543083.0 549370.0 True False 456470.4798426287 635211.7926848703 448657.72223170934 517497.27089831524 587932.8446583034 499973.9333287398 626656.0229290661 626399.5372692776 481915.27362247853 644327.8725104876 0.7084444105515533 0.9858517996589247 0.6963189726429329 0.8031582878480739 0.9124746417806624 0.7759619824930076 0.9725732032783763 0.9721751362837122 0.7479348545714737 1.0 19.2974354790408 -7.258850005875266 24.979322776348667 0.9208520596769056 0.8202015449072869 0.20945469348053525 0.10368818083406449 398.5829300226035 3845097.332090107 0.03935775791816825 0.029066883641991288 5.5099796404741815e-08 7.258850005875266 -0.10065051476961873 KGS(ph)LAALYDLAVLK ddPTM_PC-9_AZD4547_30min_R2 1 KGSLAALYDLAVLK 14 1 Q6P4R8-3;Q6P4R8;Q6P4R8-2;E9PQ59 Q6P4R8-3 NFRKB Nuclear factor related to kappa-B-binding protein 1 KGS(1)LAALYDLAVLK 131.48 7.435e-06 2980500.0 48924.0 44343.0 47621.0 53434.0 50600.0 48030.0 42015.0 47534.0 46592.0 44691.0 True False 64480.814317583005 58676.00757537305 46989.51442499138 41115.61684707052 43575.063419577375 45026.67650727462 45754.25360616007 40188.712522654976 49054.7580005468 43126.38169288171 1.4951593847305298 1.3605594828990233 1.0895770194592351 0.9533750626210528 1.0104038806197766 1.0440633955318948 1.0609342080212611 0.9318823176229594 1.1374651912577123 1.0 15.396283058461792 -5.1972958486747824 2.4173388425533333 1.0182738938735858 1.485852635337136 0.8991429386825995 0.05475870507292641 0.08455733307921212 0.9153962269431519 0.014334903881274123 0.0553254886655553 6.348982811614097e-06 5.1972958486747824 0.46757874146355016 KGS(ph)LAALYDLAVLK ddPTM_PC-9_Lapatinib_30min_R1 1 KGSLAALYDLAVLK 14 1 Q6P4R8-3;Q6P4R8;Q6P4R8-2;E9PQ59 Q6P4R8-3 NFRKB Nuclear factor related to kappa-B-binding protein 1 KGS(1)LAALYDLAVLK 115.12 7.5015e-05 2380900.0 52453.0 43015.0 48087.0 40637.0 46567.0 37935.0 36333.0 34011.0 42403.0 41052.0 True False 51705.01060129788 42915.40141033375 44133.47248118796 43625.58054105808 43828.02061424453 36312.608480804105 38214.144961265636 35591.275223259865 37627.12761661473 48147.78350164839 1.0738814300668214 0.891326625842797 0.9166252166037301 0.9060766118042488 0.9102811682441007 0.7541906571786613 0.7936844062605153 0.7392090068287642 0.7814924152287618 1.0 15.555181764227049 -6.647718100225702 5.112005778193927 0.7965605867004054 0.9370161102762475 0.35883198753294565 0.08311806507939418 0.21323980839303147 8.695188193159538 0.026670378284176333 0.02653636786243651 2.2505149370705812e-07 6.647718100225702 0.14045552357584212 KGS(ph)LSSVTPSPTPENEK ddPTM_PC-9_Lapatinib_30min_R1 1 KGSLSSVTPSPTPENEK 17 1 Q92870;Q92870-4 Q92870 APBB2 Amyloid beta A4 precursor protein-binding family B member 2 1 KGS(0.805)LS(0.156)S(0.039)VTPSPTPENEK 57.985 0.020040000000000002 6605200.0 14609.0 22161.0 20947.0 21210.0 20142.0 21209.0 19459.0 17454.0 20401.0 17649.0 True False 14400.672981037518 22109.687566067776 19224.818517758296 22769.85415448584 18957.287160695632 20301.94051059376 20466.49180638176 18264.976558959675 18103.22454794608 20699.60613418574 0.6956979223510235 1.0681211721006258 0.9287528657856051 1.1000138846546 0.9158283997195175 0.9807887347704056 0.9887382239887653 0.8823828067334464 0.8745685512367459 1.0 14.337315696372455 -10.415925529826723 14.867825057714109 0.9999965631228223 0.9461547352542675 0.024063754059271636 0.10709989936753628 0.0 0.0 0.09864183711889862 0.023924159620364233 3.837730469157416e-11 10.415925529826723 -0.05384182786855474 KGS(ph)PTPGFSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGSPTPGFSTR 11 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 KGS(0.91)PT(0.089)PGFS(0.001)TR 87.831 0.014922999999999999 148510000.0 35964.0 39982.0 33063.0 39911.0 54367.0 35876.0 38292.0 43662.0 36183.0 35050.0 True False 42051.99487862182 43951.14872816727 33851.34731212575 37674.91606320784 43714.17662677503 33994.59940391152 34664.704549927555 42515.91876371299 36712.1079234892 41404.28754435269 1.0156434845926356 1.0615120156598845 0.8175807221864124 0.9099278914738019 1.0557886445926152 0.8210405593260399 0.8372249978409695 1.0268482151315732 0.8866740644712899 1.0 15.337492550624146 -5.2342311722686725 24.6682856833482 0.9184316183343991 1.038577788662777 0.25710782139586374 0.08102948632661527 864.1247050943501 783454.0886599405 0.02055907346285877 0.05436203717419557 5.831346226916158e-06 5.2342311722686725 0.12014617032837782 KGS(ph)PTPGFSTR ddPTM_PC-9_Lapatinib_30min_R1 1 KGSPTPGFSTR 11 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 KGS(0.969)PT(0.031)PGFSTR 80.312 0.023957 106260000.0 58677.0 47478.0 53243.0 44579.0 53280.0 39902.0 36819.0 41352.0 46002.0 29238.0 True False 57840.25521995604 47368.0676080396 48865.56606392349 47857.48837118455 50146.175152510325 38195.48447610507 38725.307663249405 43273.36488289791 40820.77033746461 34291.749342813906 1.68671054491062 1.3813254942027604 1.424994845711003 1.3955977542222833 1.4623393706515246 1.1138389031794675 1.1292893598431888 1.2619176831807262 1.1903962649843325 1.0 15.065573882651465 -1.5228787452803378 0.15744373162737255 0.9657835790341361 3.4121833217930724 0.7607733990004304 0.0946296282196817 33.750017511093894 0.3454121212184046 0.31054011773578394 19.06588678344966 0.02999999999999998 1.5228787452803378 2.446399742758936 KGS(ph)QITQQSTNQSR ddPTM_PC-9_AZD4547_30min_R2 1 KGSQITQQSTNQSR 14 1 P50750;P50750-2 P50750 CDK9 Cyclin-dependent kinase 9 1 KGS(1)QITQQSTNQSR 93.495 0.0017105999999999998 8478400.0 6455.0 8576.3 7535.6 8074.5 7429.5 8945.7 8638.8 10983.0 9576.0 8612.3 True False 8507.555727659194 11348.421256312655 7435.6730203264315 6213.048774781427 6398.042167504939 8386.323964837113 9407.636464426882 9285.829714232335 10082.167810208543 8310.785998380097 1.0236764283567703 1.3655051710541748 0.894701538672246 0.7475885886115281 0.7698480226481609 1.0090891483033901 1.1319791492959363 1.117322683563539 1.2131425128951359 1.0 13.020769211999594 -7.167976223743 4.518203530269574 1.1252623867942546 0.9611760417280932 0.15978921635924537 0.16681015833787124 0.4714852106758048 16.515471068606153 0.07419247295895003 0.056486455628279794 6.79240817897811e-08 7.167976223743 -0.16408634506616138 KGS(ph)QITQQSTNQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGSQITQQSTNQSR 14 1 P50750;P50750-2 P50750 CDK9 Cyclin-dependent kinase 9 1 KGS(1)QITQQSTNQSR 164.63 4.8606e-14 0.0 4718.0 4139.8 3973.8 4037.7 4821.3 2415.3 3694.5 2931.4 4680.7 4358.1 True False 5516.664215252409 4550.7719850149315 4068.5504627204223 3811.4807594000213 3876.6008749916414 2288.637416107355 3344.530214136305 2854.453856075039 4749.146382485589 5148.189031299382 1.0715737479165612 0.8839558837773164 0.7902876988364075 0.7403536925756626 0.7530028232108648 0.4445519389814853 0.6496517889694037 0.5544578566794752 0.9224887341183982 1.0 12.329849312096258 -4.793043585986164 1.0023460457933864 0.6868441236361671 1.2620196164002373 0.31653117853877477 0.15406914635313668 2.032228656155687 1.650888084741756 0.05004991577659036 1.2629405512787992 1.6104839981815254e-05 4.793043585986164 0.5751754927640702 KGS(ph)QITQQSTNQSR ddPTM_PC-9_Lapatinib_30min_R1 2 KGSQITQQSTNQSR 14 1 P50750;P50750-2 P50750 CDK9 Cyclin-dependent kinase 9 1 KGS(0.983)QIT(0.016)QQSTNQSR;KGS(0.982)QIT(0.015)QQST(0.003)NQSR 124.04 5.779899999999999e-05 4841200.0 4966.3 14405.6 10756.599999999999 11204.099999999999 11416.900000000001 12329.2 14427.099999999999 12257.7 11725.2 12472.6 True False 4895.479651292123 14372.244718277434 9872.233869676758 12028.08688978194 10745.380388489022 11801.90885676895 15174.06464565755 12827.23749093388 10404.584504170247 14628.472291305163 0.33465419722617834 0.9824843245469983 0.6748643107144273 0.8222380745070124 0.7345524655281903 0.8067765807495662 1.0372966051059669 0.8768678803567276 0.7112557139923968 1.0 13.836491490595154 -4.751395430548517 24.975844309923183 0.840362616826151 0.3346531550606443 0.6253586710223058 0.11937712653103245 275.8847153388299 685983.0419298057 0.029456229748767694 0.3908727993029515 1.7725747944223467e-05 4.751395430548517 -0.5057094617655067 KGS(ph)SGNASEVSVACLTER ddPTM_PC-9_AZD4547_30min_R2 3 KGSSGNASEVSVACLTER 18 1 Q69YQ0-2;Q69YQ0;F8WAN1;A0A494C1J1;C9J8U1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 KGS(0.949)S(0.051)GNASEVSVACLTER;KGS(0.817)S(0.183)GNASEVSVACLTER;KGS(0.5)S(0.5)GNASEVSVACLTER 210.71 1.6682e-20 152794000.0 125500.0 124730.0 140790.0 173827.0 178902.0 155135.0 139313.0 161844.0 143141.0 142912.0 True False 165406.38943783546 165046.53327190957 138923.03260944813 133753.8707503784 154064.5453733052 145434.3839257976 151711.5871149581 136834.72860513694 150707.1410318566 137908.69437902764 1.1993905836221848 1.1967812037890548 1.007355143451889 0.9698726490932462 1.1171488938172012 1.0545700876993758 1.1000871830313659 0.9922124868288651 1.0928037692652919 1.0 17.07335388808424 -5.252417306964319 24.32853559582211 1.0441443548544804 1.1980859336477678 0.634952823819492 0.04738615800538978 279.84199783308713 754603.7407280685 0.01210540377962064 0.03101441567096731 5.59219997256045e-06 5.252417306964319 0.1539415787932874 KGS(ph)SGNASEVSVACLTER ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 KGSSGNASEVSVACLTER 18 1 Q69YQ0-2;Q69YQ0;F8WAN1;A0A494C1J1;C9J8U1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 KGS(0.799)S(0.2)GNAS(0.001)EVSVACLTER;KGS(0.5)S(0.5)GNASEVSVACLTER;KGS(0.98)S(0.02)GNASEVSVACLTER;KGS(0.755)S(0.245)GNASEVSVACLTER;KGS(0.841)S(0.159)GNASEVSVACLTER 152.13 6.330100000000001e-05 132573700.0 133042.0 129765.0 124649.0 168525.0 172378.0 132423.0 143492.0 154139.0 133571.0 113703.0 True False 155563.38290072334 142647.21161299132 127621.1048939648 159083.0906154215 138601.76832582703 125478.50476263155 129899.39896788406 150093.01457377026 135524.22318349415 134316.45382754752 1.1581856017465688 1.0620233601174422 0.950152429260982 1.1843901925796263 1.0319046131442804 0.9342005479368652 0.967114566132496 1.1174581393168606 1.0089919687538602 1.0 17.035276520835808 -6.510808901374071 24.91478154492818 1.007442972140434 1.0807953346741472 0.22183751312842992 0.07300210343156596 1014.218553096528 2093572.220707172 0.023992442491712406 0.025771517812061634 3.0845449157484375e-07 6.510808901374071 0.07335236253371313 KGS(ph)SGNASEVSVACLTER ddPTM_PC-9_Lapatinib_30min_R1 3 KGSSGNASEVSVACLTER 18 1 Q69YQ0-2;Q69YQ0;F8WAN1;A0A494C1J1;C9J8U1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 KGS(0.903)S(0.093)GNAS(0.004)EVSVACLTER;KGS(0.809)S(0.191)GNASEVSVACLTER;KGS(0.946)S(0.054)GNASEVSVACLTER 131.64 1.8623e-05 232176000.0 159326.0 184203.0 230196.0 195614.0 202818.0 190315.0 197138.0 192788.0 224380.0 159952.0 True False 157053.98202318983 183776.4892708983 211270.1734622565 210000.10610917473 190888.6439955298 182175.67109593365 207344.84103635803 201745.6342871954 199107.9615738513 187599.49007735698 0.8371770198225398 0.9796214754907796 1.1261766936314106 1.1194065933898905 1.0175328510584785 0.971088306374464 1.1052526899239385 1.0754060909440917 1.0613459636364084 1.0 17.51729638084091 -4.876038349043951 3.2187366016166084 1.0612280240969516 0.8264250100498658 0.6576787463415059 0.04901808251570101 0.17743589768245666 3.084973909847096 0.013210559480144502 0.0925442527750832 1.3303369414627607e-05 4.876038349043951 -0.2348030140470858 KGS(ph)SSSVCSVASSSDISLGSTK ddPTM_PC-9_AZD4547_30min_R2 2 KGSSSSVCSVASSSDISLGSTK 22 1 A0A087X2H1;Q9ULT8;H0YJP0 A0A087X2H1 HECTD1 E3 ubiquitin-protein ligase HECTD1 1 KGS(0.242)S(0.242)S(0.242)S(0.242)VCS(0.031)VASSSDISLGSTK;KGS(0.308)S(0.308)S(0.308)S(0.072)VCS(0.003)VASSSDISLGSTK 101.75 3.4648000000000004e-05 48165000.0 182812.0 175884.0 193097.0 215129.0 196672.0 193041.0 162529.0 184238.0 146103.0 188053.0 True False 240942.41327418052 232735.063400918 190536.4076126615 165534.33275991736 169367.48760583228 180970.11575350372 176993.76613960674 155768.25046806337 153825.70630481397 181469.3217088783 1.3277308307831326 1.282503627661554 1.0499648415412555 0.9121890752723228 0.9333119560425737 0.9972490889883006 0.9753371229521017 0.8583723628942318 0.8476678308832193 1.0 17.469366148501415 -5.347607155075519 2.29788207120961 0.930372580254715 1.329418534531241 0.8993084108935984 0.04939919868815282 0.09502894419164798 0.9494706330939398 0.014996027747549106 0.04572320947589772 4.4915149019771515e-06 5.347607155075519 0.399045954276526 KGS(ph)SSSVCSVASSSDISLGSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KGSSSSVCSVASSSDISLGSTK 22 1 A0A087X2H1;Q9ULT8;H0YJP0 A0A087X2H1 HECTD1 E3 ubiquitin-protein ligase HECTD1 1 KGS(0.249)S(0.249)S(0.249)S(0.249)VCS(0.004)VASSSDISLGSTK;KGS(0.23)S(0.23)S(0.23)S(0.23)VCS(0.07)VAS(0.008)S(0.002)SDISLGSTK 80.406 0.00023018 21996000.0 89316.0 97531.0 67363.0 90985.0 111152.0 130028.0 150328.0 180889.0 140092.0 121246.0 True False 104435.43472858907 107213.23312007604 68969.1893956001 85887.40542734977 89372.56351130841 123209.10277878812 136087.84355952992 176140.85541773794 142140.58047197422 143226.94001719222 0.729160552589151 0.7485549374105648 0.4815378265242656 0.5996595711466034 0.6239926895078579 0.8602369272428688 0.9501553516621569 1.2298025455029264 0.9924151172601495 1.0 17.127943353727098 -7.081513641345644 1.9096141794252603 1.0771450729415786 0.6303186400987996 0.795442691031881 0.0973697305755173 0.14847055043943572 1.0739364831635954 0.047096122312865016 0.03414180694575133 8.288698807635899e-08 7.081513641345644 -0.446826432842779 KGS(ph)SSSVCSVASSSDISLGSTK ddPTM_PC-9_Lapatinib_30min_R1 2 KGSSSSVCSVASSSDISLGSTK 22 1 A0A087X2H1;Q9ULT8;H0YJP0 A0A087X2H1 HECTD1 E3 ubiquitin-protein ligase HECTD1 1 KGS(0.247)S(0.247)S(0.247)S(0.247)VCS(0.011)VASSSDISLGSTK;KGS(0.249)S(0.249)S(0.249)S(0.249)VCS(0.003)VASSSDISLGSTK 110.78 6.954199999999999e-06 25635000.0 96785.0 95466.0 92346.0 96637.0 135389.0 175971.0 178209.0 169409.0 202964.0 197205.0 True False 95404.82815180477 95244.95434241334 84753.6683458686 103744.00735158165 127425.68520501541 168445.1305384365 187435.79003666624 177280.36059796 180104.0570143289 231291.62149085503 0.41248717760222436 0.41179595580888434 0.3664363966129212 0.4485420037391348 0.5509308308863824 0.7282802958995063 0.8103872886899071 0.7664798208220848 0.778688202596435 1.0 17.81935347991577 -6.684295409102419 1.2604904783590232 0.8341031860720258 0.39207652800713544 0.9132630760065484 0.060596062498683816 0.11933946938151094 0.3991097672451219 0.0279754835726191 0.027098308457460363 2.0687337079282908e-07 6.684295409102419 -0.4420266580648904 KGS(ph)VSHDTVQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGSVSHDTVQPR 12 1 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;F2Z3L2;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 KGS(0.994)VS(0.005)HDT(0.001)VQPR 58.723 0.030751999999999998 3084900.0 8274.4 9301.2 13203.0 10739.0 14679.0 13558.0 12349.0 15099.0 13236.0 10175.0 True False 9675.092493150603 10224.561666510668 13517.809592656326 10137.328646307755 11802.755324083193 12846.99461250507 11179.213320982326 14702.667248712905 13429.55145994813 12019.64695474431 0.8049398230728998 0.8506540753657412 1.1246428155130357 0.8433965393889061 0.9819552411582682 1.0688329416725668 0.9300783428226854 1.2232195591160497 1.1172999931289422 1.0 13.553106900879769 -3.0691739305378185 0.32727186017285026 1.0927910090654394 4.4553363052559806e-11 0.38697872921446497 0.10317508954327415 22.52642928702492 0.79655548657658 0.09954881099508373 12.203443674873547 0.000852758524475432 3.0691739305378185 -1.0927910090208859 KGS(ph)VVNVNPTNTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGSVVNVNPTNTR 13 1 Q8N4C8;Q8N4C8-4;Q8N4C8-3;Q8N4C8-2;Q8N4C8-5;C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6;E7EN19 Q8N4C8;Q8N4C8-3;C9J840;O95819-6;E7EN19 MINK1;MAP4K4 Misshapen-like kinase 1 1 KGS(1)VVNVNPTNTR 65.265 0.018404 3327300.0 29938.0 27910.0 16714.0 15262.0 21131.0 11783.0 7423.6 17529.0 10872.0 8727.4 True False 35005.91209754699 30680.720349235893 17112.525148197972 14406.919620071607 16990.532240152734 11165.078737213991 6720.382865790306 17068.88232351072 11030.982432196739 10309.608533939614 3.3954647242236433 2.975934561262324 1.6598617776672029 1.3974264466631776 1.6480288445695364 1.0829779521170118 0.6518562604648427 1.6556285592531788 1.0699710271134286 1.0 13.331701932734013 -5.185271069380097 1.3230747031391104 1.187864521861362 3.7491426935394685 0.8829928243821763 0.2850696694931248 0.22571687932802129 0.5622029239325717 0.08973667335019313 0.6404810690285583 6.52723021672354e-06 5.185271069380097 2.5612781716781066 up KGS(ph)VVNVNPTNTR ddPTM_PC-9_Lapatinib_30min_R1 1 KGSVVNVNPTNTR 13 1 Q8N4C8;Q8N4C8-4;Q8N4C8-3;Q8N4C8-2;Q8N4C8-5;C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6;E7EN19 Q8N4C8;Q8N4C8-3;C9J840;O95819-6;E7EN19 MINK1;MAP4K4 Misshapen-like kinase 1 1 KGS(1)VVNVNPTNTR 53.773 0.038857 1567700.0 13836.0 12853.0 14430.0 19789.0 11660.0 8254.1 9347.8 7468.4 10696.0 12245.0 True False 13638.696102788344 12823.239668185974 13243.621101410808 21244.349074168804 10974.181724442009 7901.091384246881 9831.783344863326 7815.409128734643 9491.30384612672 14361.531934563109 0.9496686122992802 0.8928880099012967 0.9221593602795336 1.4792536876265405 0.7641372643562523 0.5501565863758419 0.6845915456415701 0.5441904919575974 0.660883803299878 1.0 13.809922028189334 -6.50532314251788 24.69899018517292 0.6590301350774717 1.0493967338922208 0.4523723304009044 0.19425907769255585 555.4449241019591 781457.0690109617 0.060342108129934326 0.06693879826520117 3.1237542318108555e-07 6.50532314251788 0.3903665988147491 KGSDDAPYS(ph)PTAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGSDDAPYSPTAR 13 1 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 KGSDDAPY(0.001)S(0.737)PT(0.262)AR 69.069 0.014379 5191500.0 35662.0 30704.0 36168.0 42289.0 49450.0 34830.0 42251.0 39421.0 32194.0 27552.0 True False 41698.87224339369 33752.090204333166 37030.38228790382 39919.68443278785 39760.627479795185 33003.45348528928 38248.67940924969 38386.24052000208 32664.77634493581 32546.959498487995 1.2811910201728938 1.037027443558934 1.1377524309029268 1.2265257660901432 1.2216387672600357 1.0140257029791828 1.175184410421704 1.179410953019601 1.003619903310885 1.0 14.990235154235641 -8.268003343965653 23.557569929478785 1.0018098692465247 1.1543474684283754 0.3939066276878781 0.07786244599620672 266.101858721883 954989.1349945739 0.06784314843300845 0.019257149143223427 5.395064684258621e-09 8.268003343965653 0.15253759918185072 KGSDDAPYS(ph)PTAR ddPTM_PC-9_Lapatinib_30min_R1 1 KGSDDAPYSPTAR 13 1 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 KGSDDAPY(0.003)S(0.806)PT(0.191)AR 64.89 0.018801 8703900.0 38765.0 32202.0 30925.0 24438.0 28360.0 30265.0 24569.0 29338.0 27546.0 22918.0 True False 38212.20399136962 32127.438247484977 28382.465873952136 26235.252042778175 26691.920557905254 28970.63650116084 25841.06260295973 30701.150583634626 24443.479407760533 26879.34576368456 1.4216195709270707 1.1952462879840948 1.0559210080290857 0.9760375968013109 0.993027166381686 1.0778028883538426 0.9613724541566928 1.1421836994676235 0.909377766209808 1.0 14.714210403269751 -4.8432132363654254 1.6410371463547124 1.01419203694457 1.537525494198015 0.8170827250404791 0.06077682973822129 0.3314418078985227 0.9653032591386099 0.016037525299053182 0.2686469582402096 1.4347847883995651e-05 4.8432132363654254 0.5233334572534449 KGSDDAPYSPT(ph)AR ddPTM_PC-9_AZD4547_30min_R2 1 KGSDDAPYSPTAR 13 1 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 KGSDDAPYS(0.118)PT(0.882)AR 65.477 0.033666 8097300.0 26491.0 28320.0 39352.0 45899.0 46847.0 44247.0 37471.0 32715.0 27493.0 35656.0 True False 34914.58695296977 37473.886172215825 38830.16676785998 35317.69468248098 40343.1026880818 41480.22809530251 40805.84640905447 27659.648465911952 28946.22385192808 34407.694292841734 1.0147319566319644 1.0891135527210258 1.1285314975592045 1.0264475841331968 1.1725023578948413 1.2055509370162059 1.185951202128177 0.8038797435975341 0.8412718273293345 1.0 15.07044359787442 -7.761994986583102 24.999998505936603 0.8669318038760315 1.1188705169387363 0.668454441181736 0.07589239115657259 8.502899198112479 382525.8778439207 0.03995041551050407 0.021019737118165457 1.7298363280173383e-08 7.761994986583102 0.25193871306270477 KGSDDAPYSPT(ph)AR ddPTM_PC-9_Lapatinib_30min_R1 1 KGSDDAPYSPTAR 13 1 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 KGSDDAPY(0.001)S(0.398)PT(0.601)AR 63.614 0.037993 8389600.0 43649.0 37756.0 47341.0 36476.0 41534.0 43457.0 35016.0 32550.0 45796.0 34332.0 True False 43026.55725575375 37668.57830172174 43448.80572154466 39158.566720368945 39091.05177898581 41598.44541321482 36828.95714539615 34062.39182961712 40637.972226740785 40266.240455485575 1.0685516395134955 0.9354878398286138 1.0790380534675796 0.9724912551411109 0.9708145418294282 1.0330849104028472 0.9146361003359786 0.8459292808146113 1.0092318470026065 1.0 15.297283157782333 -7.266896842423053 24.972028792477015 0.9296100773456911 1.0061925645800547 0.2212817878022908 0.05985476048380759 600.1203848232906 2745989.127720077 0.023390078577560237 0.016281481575495492 5.408827830885474e-08 7.266896842423053 0.07658248723436356 KGSDS(ph)DPSQEAHSQTEK ddPTM_PC-9_AZD4547_30min_R2 1 KGSDSDPSQEAHSQTEK 17 1 Q8WYA1-6;Q8WYA1-4;Q8WYA1-3;Q8WYA1-9 Q8WYA1-6 ARNTL2 Aryl hydrocarbon receptor nuclear translocator-like protein 2 1 KGS(0.166)DS(0.828)DPS(0.005)QEAHSQTEK 85.945 0.010877 0.0 3741.9 2974.9 3835.1 6514.2 5406.9 5533.6 4021.0 5798.8 4639.7 4439.8 True False 4931.7463636449165 3936.478247659775 3784.244068190177 5012.451833386732 4656.245264887602 5187.583117232037 4378.861210290839 4902.728703167666 4884.945069864719 4284.363953369946 1.1511035050525433 0.9188010847125779 0.8832685806754605 1.1699407165080116 1.086799654643053 1.210817562114826 1.022056309396069 1.144330583612378 1.1401797613441254 1.0 12.064865325772432 -5.771984151796051 24.99973622092414 1.1160990805140703 0.9778320469545622 0.29561000634928836 0.08881376703554285 225.85981931818105 535472.8135533199 0.024239416491846154 0.03638288751029912 1.6905026200657218e-06 5.771984151796051 -0.1382670335595081 KGSGDYMPMS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 KGSGDYMPMSPK 12 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 KGS(0.002)GDY(0.001)MPMS(0.997)PK;KGS(0.002)GDY(0.014)MPMS(0.985)PK 57.498999999999995 0.026862999999999998 17405600.0 97166.0 93077.0 109054.0 151013.0 156509.0 132235.0 117812.0 132198.0 125811.0 137809.0 True False 128062.76682164703 123162.32003006118 107607.87270538234 116199.28597759227 134780.4268919886 123966.32454589766 128297.03976791471 111769.83670782892 132461.11261175282 132984.3488557951 0.9629912686982066 0.9261414676971897 0.8091769718109431 0.873781666620001 1.0135059354852436 0.9321873258959491 0.964752926730023 0.840473617154973 0.9960654298904777 1.0 17.020896937029406 -6.220946835551505 24.99468516857053 0.9489185263516565 0.8893994577312294 0.21564393819165595 0.058940596282573185 913.9864781342792 564172.9958800005 0.017770175850516566 0.022940913655824888 6.012473350717407e-07 6.220946835551505 -0.05951906862042711 KGSGDYMPMS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 KGSGDYMPMSPK 12 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 KGSGDYMPMS(1)PK;KGS(0.001)GDYMPMS(0.999)PK 77.372 0.0065655 6463600.0 80532.0 68184.0 72894.0 66974.0 87337.0 99336.0 83693.0 85537.0 98178.0 73027.0 True False 79383.59891223996 68026.12413721262 66900.9366989771 71899.49137871455 82200.00937114844 95087.630843526 88026.21402700599 89511.3612881708 87120.15977982698 85649.61964763884 0.926841231039003 0.7942373173059145 0.7811002194079375 0.8394607200184647 0.9597241611733707 1.1101932645435553 1.027747868456911 1.0450876682981092 1.0171692546708078 1.0 16.386159219160724 -6.400928637632444 3.1686528728406405 1.0419444784629808 0.8276754552787113 0.8133852328791861 0.046002037097376366 0.10245065989449594 1.943809496422828 0.015151924814728362 0.01729636344205092 3.972568205226293e-07 6.400928637632444 -0.21426902318426944 KGSIT(ph)EYTAAEEK ddPTM_PC-9_AZD4547_30min_R2 1 KGSITEYTAAEEK 13 1 J3KN59;Q12982;Q12982-2 J3KN59 BNIP2 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 1 KGS(0.327)IT(0.673)EYTAAEEK 140.93 0.00025552 22342000.0 30615.0 29063.0 30102.0 27808.0 24086.0 32974.0 42929.0 36307.0 35656.0 31065.0 True False 40349.93316844096 38457.0463920589 29702.827811702595 21397.29522931723 20742.07465462331 30912.130567371903 46749.59783550747 30696.587401860434 37540.70336683328 29977.42380545009 1.3460106989282075 1.2828669548671212 0.9908399068735996 0.7137803224247397 0.6919231882378187 1.0311803565238944 1.5594935088120578 1.0239901734411079 1.2522991838947861 1.0 14.871588786090795 -7.026500891617553 24.95433827597385 1.2230009161545958 0.9893426648314197 0.13931123077414753 0.24107760668707132 1436.4736747661666 1352639.0431569885 0.0999866225929713 0.07771119188491116 9.408038985404142e-08 7.026500891617553 -0.23365825132317608 KGSLAALYDLAVLK ddPTM_PC-9_AZD4547_30min_R2 1 KGSLAALYDLAVLK 14 1 Q6P4R8-3;Q6P4R8;Q6P4R8-2;E9PQ59 Q6P4R8-3 NFRKB Nuclear factor related to kappa-B-binding protein 0 144.29 0.00011018 911310.0 11218.0 9237.9 10840.0 12229.0 11934.0 10309.0 9035.8 12491.0 11446.0 11944.0 False True 14785.090651104709 12223.87051801951 10696.254517269826 9409.792986166585 10277.170095834705 9664.376600322583 9839.968695335981 10560.80296462497 12051.012192527876 11525.84419547066 1.2827772439362701 1.0605618391773122 0.9280235213897097 0.8164081369297336 0.8916631113123454 0.8384962035249807 0.8537308442190134 0.9162715359951747 1.045564384538843 1.0 13.492584802396307 -4.866485414482956 1.9092610941387693 0.8981757571355518 1.3609663121026594 0.7446997101788874 0.06729547231279234 0.3198526680905583 1.4414609258819946 0.018910907722719653 0.2509535989397956 1.3599238347356278e-05 4.866485414482956 0.46279055496710764 KGSLAALYDLAVLK ddPTM_PC-9_Lapatinib_30min_R1 1 KGSLAALYDLAVLK 14 1 Q6P4R8-3;Q6P4R8;Q6P4R8-2;E9PQ59 Q6P4R8-3 NFRKB Nuclear factor related to kappa-B-binding protein 0 161.82 6.7062e-13 0.0 14701.0 10480.0 10462.0 10984.0 12016.0 8504.6 10970.0 8976.7 9457.2 11279.0 False True 14491.361044166777 10455.734203889275 9601.854744487868 11791.800001549856 11309.24250436494 8140.878083190894 11537.97292337776 9393.790253054507 8392.03054726904 13228.56012167719 1.09546019452414 0.7903909501651522 0.7258427717128213 0.8913895309155405 0.854911071223305 0.6154016770011662 0.8722017224286471 0.7101143409902355 0.6343873006645149 1.0 13.69136841785802 -4.762092547016287 6.295242024515556 0.7791588434125565 1.1053066657161088 0.39124688373804206 0.11452023404355048 0.12275252244837527 21.13009100618013 0.027353218164214113 0.17236613847790896 1.7294477791540084e-05 4.762092547016287 0.3261478223035523 KGTDVNVFNTILTTR ddPTM_PC-9_Lapatinib_30min_R1 2 KGTDVNVFNTILTTR 15 1 P04083 P04083 ANXA1 Annexin A1 0 ; 96.435 0.0016737000000000002 13187700.0 88663.0 94708.0 99889.0 98162.0 104266.0 92556.0 102713.0 93001.0 93014.0 89088.0 False True 87398.6493611972 94488.70944484226 91676.51200269036 105381.16093883288 98133.27887484302 88597.59563857403 108030.97656143112 97322.16597684257 82537.78383915771 104486.74209770179 0.8364568327671071 0.9043129065742069 0.8773985116405195 1.0085601179936756 0.9391935943708736 0.8479314586699392 1.0339204227500485 0.9314307635875958 0.789935471066555 1.0 16.672960370586722 -4.733710537939809 1.3793926469823936 0.9313687535307158 0.7937918584762576 0.13730866915554718 0.07120762606908328 2.995845145729948 4.731373012303235 0.02062567505294356 0.5964917989840889 1.8462455522003246e-05 4.733710537939809 -0.13757689505445825 KGTVEGFEPADNK ddPTM_PC-9_Lapatinib_30min_R1 1 KGTVEGFEPADNK 13 1 H0YLA2;P37108 H0YLA2 SRP14 Signal recognition particle 14 kDa protein 0 149.35 7.6658e-05 5142400.0 39289.0 49677.0 44346.0 47447.0 44776.0 32008.0 44508.0 48050.0 33324.0 41143.0 False True 38728.73165527981 49561.975958645766 40700.04306051034 50936.41065855208 42142.36371300303 30639.09245429229 46812.406460683465 50282.57841514909 29570.700202723147 48254.51273039855 0.8025929485944668 1.0270951493293925 0.8434453226769572 1.0555781786283385 0.8733351831455737 0.6349477120507903 0.9701145822822368 1.0420285185777647 0.6128069382429947 1.0 15.558376248133873 -6.505443310963521 24.847942958940767 0.8500066372947134 0.9365992926772063 0.059994593943320296 0.1500970374491372 2062.544330106815 2939421.083372495 0.046184988750300734 0.05123721347069538 3.122890014607948e-07 6.505443310963521 0.08659265538249294 KGVAINMVTEEDKR ddPTM_PC-9_Lapatinib_30min_R1 1 KGVAINMVTEEDKR 14 2 P60842 P60842 EIF4A1 Eukaryotic initiation factor 4A-I 0 96.06700000000001 0.012320999999999999 7886100.0 29653.0 24846.0 30358.0 22446.0 24410.0 21014.0 20796.0 20595.0 19784.0 17950.0 False True 29230.142782305782 24788.470613533704 27862.08242526886 24096.753717660984 22974.251791906478 20115.28020602657 21872.715124390517 21551.91888574393 17555.7175852441 21052.63358312845 1.3884316499827736 1.1774522420510443 1.3234487892097972 1.1445956926249878 1.0912768562275272 0.9554757188263101 1.0389538695015943 1.0237160496165005 0.8338965059133138 1.0 14.36171309833577 -6.167893082189616 0.908771845811838 0.9596385278989961 1.3185643504164022 0.7841730913746437 0.07380381850860057 0.2773627389231291 0.4814518317555746 0.03422567329656565 0.06218866548628975 6.79370864548281e-07 6.167893082189616 0.3589258225174061 KGVDLLLEGVQGESSPT(ph)RR ddPTM_PC-9_AZD4547_30min_R2 1 KGVDLLLEGVQGESSPTRR 19 2 F5H7T0;F6RJM5;Q96S38-2;Q96S38 F5H7T0 RPS6KC1 Ribosomal protein S6 kinase delta-1 1 KGVDLLLEGVQGES(0.158)S(0.158)PT(0.683)RR 54.292 0.015811000000000002 5180300.0 23499.0 19057.0 24850.0 40093.0 40980.0 24938.0 23983.0 30148.0 29278.0 29980.0 True False 30971.193190435868 25216.80257005357 24520.472763298432 30850.17828067519 35290.63436629013 23378.6229177267 26117.44053877274 25489.319332120238 30825.575307778367 28930.40932520179 1.0705411334590527 0.8716365636792691 0.8475674328582077 1.0663581677636707 1.219845663764869 0.8080985877154933 0.9027677501963782 0.8810562977384507 1.0655077486555182 1.0 14.820299115096986 -4.7203845791107595 23.031396184040826 0.9598190402851277 1.070544214599327 0.06728658690094524 0.12025104485472587 10136.63518023522 5685544.142426503 0.03138614688515661 9.772007017222547 1.903774129581795e-05 4.7203845791107595 0.11072517431419926 KGVEGLIDIENPNR ddPTM_PC-9_Lapatinib_30min_R1 1 KGVEGLIDIENPNR 14 1 Q13442 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 0 82.48299999999999 0.005815399999999999 2854300.0 14536.0 15746.0 16383.0 16225.0 17134.0 15375.0 14177.0 18099.0 21060.0 17801.0 False True 14328.713974424076 15709.541104431359 15036.052980208824 17418.240625013328 16126.211806740084 14717.447090875532 14911.015691406246 18939.94561364793 18688.001028368417 20877.879131658465 0.6863108021684314 0.7524490876379285 0.7201906326494962 0.8342916689560165 0.7724066082117927 0.7049301798360603 0.7142016484229817 0.9071776636989951 0.8951101263935667 1.0 14.349687543485704 -7.818792911660214 5.584492829360543 0.9306705376510772 0.7438059680004752 0.7838159376553608 0.046590599342440475 0.09825785943044692 6.212515571386746 0.02687332791823007 0.012823026501551186 1.517773928014641e-08 7.818792911660214 -0.18686456965060205 KGVNLPGAAVDLPAVSEK ddPTM_PC-9_AZD4547_30min_R2 2 KGVNLPGAAVDLPAVSEK 18 1 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ; 132.13 2.5521e-05 19073900.0 154308.0 169549.0 207495.0 196810.0 192497.0 224450.0 194282.0 226530.0 201465.0 201836.0 False True 203374.73419421178 224352.3985385955 204743.48072517535 151438.4951841888 165772.11429008658 210415.1060182762 211572.72162589495 191524.99364154148 212114.0286010509 194769.7830740969 1.044180113487323 1.1518850357462502 1.0512076231418512 0.7775256140557314 0.8511182364824084 1.080327259687029 1.0862707668848492 0.9833403858578977 1.0890499812301773 1.0 17.57141034697726 -9.863505755666733 15.540389138078119 1.0000035475677056 1.0095997050463696 0.00046968995541962766 0.10955803729862851 0.0 0.0 0.11717092897860344 0.028418124495913372 1.3692862412403247e-10 9.863505755666733 0.009596157478664047 KGVNLPGAAVDLPAVSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KGVNLPGAAVDLPAVSEK 18 1 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ; 180.62 4.8039999999999995e-09 32607000.0 192817.0 224587.0 217059.0 215522.0 232332.0 189669.0 225488.0 176470.0 186233.0 180069.0 False True 225457.10979065768 246882.51311622484 222234.50976084181 203447.0010717518 186808.21240921735 179722.4237468082 204128.14424825198 171837.8494854202 188956.3053067787 212714.08427458003 1.0599068254438122 1.1606307779673808 1.0447569116954778 0.9564340874068973 0.8782127100153729 0.8449013818700183 0.9596362410340212 0.8078348458751086 0.8883112086873672 1.0 17.698556034958635 -5.7808328405825415 2.1367776924805524 0.8881135427785708 1.1105652824145291 0.7000205936762477 0.05672397173443193 0.15178946168682816 1.414908637628577 0.01634237426975504 0.03087369638406619 1.6564073899775276e-06 5.7808328405825415 0.22245173963595832 KGVNLPGAAVDLPAVSEK ddPTM_PC-9_Lapatinib_30min_R1 2 KGVNLPGAAVDLPAVSEK 18 1 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ; 197.1 8.425799999999999e-15 64855000.0 375630.0 386030.0 411350.0 396380.0 379710.0 334670.0 413280.0 376530.0 346490.0 380000.0 False True 370273.4473178951 385136.1712526134 377530.3908569193 425531.10748491687 357376.20433858305 320356.9442538745 434677.61620542913 394024.9583903445 307464.6474985461 445682.49368182855 0.8308009683284356 0.8641492019822548 0.8470837338440247 0.9547853315250526 0.8018627821484792 0.7188008252407966 0.9753078085129909 0.8840934162238775 0.6898737371498469 1.0 18.76565676773103 -11.14559312989236 5.173009066544347 1.001726950032637 0.845481073951316 0.23652511898887796 0.08545406473075494 0.001713167755938555 0.00012494708823508873 0.08328384488563381 0.019984466956323915 7.151660177863563e-12 11.14559312989236 -0.1562458760813209 KGVNLPGAAVDLPAVSEKDIQDLK ddPTM_PC-9_AZD4547_30min_R2 1 KGVNLPGAAVDLPAVSEKDIQDLK 24 2 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 123.83 7.5807e-08 3346300.0 42542.0 28196.0 60613.0 87971.0 73089.0 50805.0 35656.0 50891.0 41674.0 61473.0 False True 56069.47107142952 37309.80559716799 59809.23201616935 67690.64508840143 62941.853957974155 47628.15531859431 38829.314925175364 43026.965308840736 43876.8025608428 59320.84898092498 0.9451899633037794 0.6289492857589616 1.008232907040852 1.1410936669191605 1.0610410174374534 0.8028906554238538 0.6545643832181363 0.7253261888189825 0.7396523029357129 1.0 15.856251624877489 -6.930211686351498 7.136042037267397 0.7530373505765079 0.951044777094804 0.2398782489739094 0.1506530267880496 0.319709888562481 27.0712719240606 0.05696957989425133 0.050167110898893794 1.1743250190607381e-07 6.930211686351498 0.19800742651829606 KGVNLPGAAVDLPAVSEKDIQDLK ddPTM_PC-9_Lapatinib_30min_R1 2 KGVNLPGAAVDLPAVSEKDIQDLK 24 2 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ; 109.37 3.2632e-06 5323200.0 105804.0 75740.0 86561.0 77688.0 85136.0 82976.0 60028.0 54026.0 85673.0 60293.0 False True 104295.21555792255 75564.6286834516 79444.28871512272 83401.43467957074 80128.467863816 79427.30990650324 63135.95612074025 56536.245191609676 76023.6045633147 70714.56471462747 1.4748760171092286 1.0685864925902724 1.1234501553636727 1.179409574479343 1.133125377879067 1.1232100519466752 0.8928281801002225 0.7994993028630638 1.075077034980165 1.0 16.109719769654905 -7.1323141413970665 3.476167739965731 0.9253294837292966 1.1807822554696692 0.48559810836702244 0.12259275298830682 0.21688672195117714 4.803415142179151 0.049025930409030374 0.03709121357648242 7.373706694725388e-08 7.1323141413970665 0.2554527717403726 KGVSASAVPFTPS(ph)SPLLSCSQEGSR ddPTM_PC-9_AZD4547_30min_R2 1 KGVSASAVPFTPSSPLLSCSQEGSR 25 1 J3QRU8;Q9Y2X7;Q9Y2X7-3;J3QL89 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 KGVSASAVPFT(0.001)PS(0.499)S(0.499)PLLS(0.001)CSQEGSR 173.09 2.4197e-12 16319000.0 84084.0 77428.0 125600.0 182420.0 147490.0 124830.0 109360.0 149120.0 111860.0 141050.0 True False 110820.96294415096 102455.08681293517 123934.46193441785 140365.88736090515 127013.55936271699 117024.36036650186 119092.82814160798 126076.93043670426 117772.69123328384 136111.88243227854 0.8141902159004312 0.7527269844637623 0.9105337441503722 1.0312537366511199 0.9331555562455147 0.8597659386918439 0.8749627586765744 0.926274239866111 0.8652638485980882 1.0 17.05443349262206 -5.299432761737372 7.792162407889434 0.9226790770148858 0.7835369416008093 0.5214885104900682 0.05426186796281841 0.19960930344339733 37.21774768083771 0.014883507289362856 0.031634065953494266 5.018422691565594e-06 5.299432761737372 -0.1391421354140765 KGVSASAVPFTPS(ph)SPLLSCSQEGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGVSASAVPFTPSSPLLSCSQEGSR 25 1 J3QRU8;Q9Y2X7;Q9Y2X7-3;J3QL89 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 KGVSASAVPFT(0.024)PS(0.704)S(0.253)PLLS(0.017)CS(0.003)QEGSR 107.95 2.1218000000000004e-07 8259300.0 34902.0 30515.0 45599.0 53155.0 90006.0 81320.0 76320.0 78762.0 83190.0 58995.0 True False 40810.219254077914 33544.32753339066 46686.253095170505 50176.89768083516 72369.97041347699 77055.43604432157 69090.41709104972 76694.58095523708 84406.4963699824 69690.32649583704 0.5855937445854227 0.481334056246593 0.6699100928729228 0.7199980284757667 1.0384507298555994 1.1056833841770635 0.991391783695788 1.1005054045745994 1.2111651733332665 1.0 16.08867079339023 -6.093984971308003 1.6004545098013876 1.090352704556956 0.5465052728780512 0.9152563883137437 0.06982980863031785 0.09838325213742424 0.5041917119809451 0.02431193627669891 0.037956549347918464 8.054063116751274e-07 6.093984971308003 -0.5438474316789049 KGVSASAVPFTPSS(ph)PLLSCSQEGSR ddPTM_PC-9_AZD4547_30min_R2 1 KGVSASAVPFTPSSPLLSCSQEGSR 25 1 J3QRU8;Q9Y2X7;Q9Y2X7-3;J3QL89 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 KGVSASAVPFTPS(0.028)S(0.968)PLLS(0.002)CS(0.001)QEGSR 139.64 5.983500000000001e-07 16143000.0 34077.0 36936.0 53892.0 83438.0 64431.0 56658.0 54804.0 69048.0 49274.0 59414.0 True False 44912.77715436755 48874.83967715263 53177.356867592716 64202.65820424959 55485.86781001558 53115.16630333467 59681.44983058421 58378.21816519295 51878.523045135305 57333.933944214135 0.7833541859881382 0.852459203736269 0.9275023220861529 1.1198020750977722 0.9677666260264519 0.9264176143052678 1.0409446156032867 1.0182140688618175 0.9048484811039316 1.0 15.807101651906994 -5.276977371211158 2.6650811865937407 0.9961583108499005 0.8018745864728555 0.5951904506594241 0.05858575972864268 0.19212041583253178 2.6461290559769464 0.016072590453522183 0.049711324277102606 5.284727869801084e-06 5.276977371211158 -0.194283724377045 KGVSASAVPFTPSS(ph)PLLSCSQEGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KGVSASAVPFTPSSPLLSCSQEGSR 25 1 J3QRU8;Q9Y2X7;Q9Y2X7-3;J3QL89 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 KGVSASAVPFTPS(0.267)S(0.732)PLLS(0.001)CSQEGSR 133.07 1.4169e-07 8612300.0 15614.0 15718.0 16089.0 25087.0 36082.0 37644.0 37797.0 28115.0 30877.0 24257.0 True False 18257.141809442797 17278.37916335684 16472.622777872286 23681.45672315137 29011.99111680424 35669.88237152536 34216.59453341723 27377.011040304853 31328.517711455006 28654.602081693665 0.6371451872684211 0.6029879289231288 0.5748683136799173 0.8264451432840015 1.0124723084303062 1.244822115129405 1.194104682935971 0.9554141063363425 1.093315399115928 1.0 14.806479241646713 -6.093553957716732 2.2267665644819257 1.1008613709597697 0.6037804086906102 0.8712711007190779 0.08298147760640028 0.1063112135360744 1.040021050339512 0.028523950177271933 0.04128401615911893 8.062060302936904e-07 6.093553957716732 -0.49708096226915943 KGVSASAVPFTPSS(ph)PLLSCSQEGSR ddPTM_PC-9_Lapatinib_30min_R1 2 KGVSASAVPFTPSSPLLSCSQEGSR 25 1 J3QRU8;Q9Y2X7;Q9Y2X7-3;J3QL89 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 KGVSASAVPFTPS(0.096)S(0.873)PLLS(0.023)CS(0.008)QEGSR;KGVSASAVPFT(0.023)PS(0.211)S(0.751)PLLS(0.011)CS(0.003)QEGS(0.001)R 128.37 2.9993e-09 18816500.0 77774.0 69935.0 73842.0 61860.4 73305.0 86009.0 82828.0 75213.0 87848.0 74710.0 True False 76664.92849799519 69773.06980429367 67770.99579836283 66409.82017624509 68993.34402317513 82330.59556677153 87116.42855948348 78707.67055855598 77953.63315954928 87623.5239551823 0.8749354629609257 0.796282398320127 0.773433807946669 0.7578994450190385 0.7873838086957545 0.9395946642009285 0.9942127938616325 0.8982481758986708 0.8896427539186967 1.0 16.41903061624219 -6.763456689048728 24.721784372151735 0.941097286025055 0.794301119590715 0.7367436654068953 0.04369308884720701 25.218396097342275 309043.1630624977 0.015605089973257796 0.014452242067790277 1.7240240144569093e-07 6.763456689048728 -0.14679616643434001 KGVSQTGT(ph)PVCEEDGDAGLGIR ddPTM_PC-9_Lapatinib_30min_R1 1 KGVSQTGTPVCEEDGDAGLGIR 22 1 Q12888;Q12888-3;Q12888-2 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 KGVS(0.015)QT(0.027)GT(0.958)PVCEEDGDAGLGIR 55.621 0.010952 4337400.0 10451.0 12790.0 14413.0 10759.0 13183.0 12772.0 13071.0 12084.0 16207.0 12122.0 True False 10301.966823521323 12760.385540815254 13228.018775788914 11550.252750971862 12407.601858775217 12225.771332986165 13747.752423105807 12645.466754810848 14381.596992723986 14217.271548450299 0.7246092746005298 0.8975270323373793 0.930418943656653 0.8124099417817517 0.8727132921736774 0.8599238814087918 0.9669754408400767 0.8894439915364225 1.0115581561281777 1.0 13.795357001946448 -7.598918069807228 0.5000087201114078 1.0116251891966914 0.8331810052819242 0.5151974793201719 0.057686043584519446 0.808450063260765 0.45640693447195235 0.05820078113289499 0.043111629407428124 2.5181519354385498e-08 7.598918069807228 -0.17844418391476724 KGWDAEGS(ph)PFR ddPTM_PC-9_Lapatinib_30min_R1 1 KGWDAEGSPFR 11 1 Q8IVD9 Q8IVD9 NUDCD3 NudC domain-containing protein 3 1 KGWDAEGS(1)PFR 53.49100000000001 0.043072000000000006 6213000.0 58854.0 64457.0 68700.0 67091.0 53754.0 54277.0 49112.0 42612.0 56512.0 41521.0 True False 58014.731167498205 64307.75377672627 63051.75118966889 72025.0959490152 50592.295404430195 51955.699235866785 51654.77905313845 44591.90908275409 50147.02346225813 48697.84952674519 1.1913201862360703 1.3205460693168396 1.2947543228790923 1.4790200521987842 1.0389020438498946 1.0668992520364244 1.0607199199785875 0.9156853847984379 1.029758479062141 1.0 15.571570444555194 -6.347854514429537 7.537783648070788 1.0174670578196578 1.3189640278667183 0.7916872383840825 0.07610384897036356 0.12858925369181845 9.925172658719147 0.024138856256345417 0.027385981928129088 4.4889574163723846e-07 6.347854514429537 0.30149697004706044 KGWS(ph)MSEQSEESVGGR ddPTM_PC-9_AZD4547_30min_R2 1 KGWSMSEQSEESVGGR 16 1 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 KGWS(0.794)MS(0.205)EQSEESVGGR 128.88 1.8646e-05 4976000.0 28479.0 30142.0 38406.0 54684.0 71110.0 49057.0 50513.0 57582.0 52534.0 50084.0 True False 37534.72960000096 39884.81204106386 37896.71134596539 42077.44865937801 61237.60394794749 45989.45803492335 55008.55914335269 48684.025002724775 55310.8399897134 48330.57440438314 0.776624943166347 0.8252501140860986 0.7841146481910737 0.8706175992719419 1.2670572345275872 0.951560344599433 1.1381730885938721 1.0073131884463924 1.1444275320819943 1.0 15.560648520713402 -6.066725960913426 7.248435556108265 1.080961168123301 0.8027438851644992 0.7132387979638662 0.08499713457307981 0.13458026059235859 12.798157053687593 0.023185984224031373 0.03018710988556687 8.575788053216562e-07 6.066725960913426 -0.27821728295880166 KGWS(ph)MSEQSEESVGGR ddPTM_PC-9_Lapatinib_30min_R1 1 KGWSMSEQSEESVGGR 16 1 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 KGWS(0.966)MS(0.034)EQSEESVGGR 146.1 2.8641e-05 3124600.0 22657.0 16889.0 21494.0 25036.0 24509.0 18076.0 16632.0 20408.0 25266.0 38802.0 True False 22333.907025215078 16849.894558157062 19726.846289239373 26877.230957647713 23067.428806547967 17302.93161721406 17493.123578998995 21356.23018306687 22420.277017224904 45508.87399958496 0.490759385200758 0.3702551409712034 0.4334725198742399 0.5905931875592623 0.5068775994492489 0.380210057875127 0.3843892859040751 0.4692761720112354 0.49265725663591187 1.0 15.473860270507027 -9.053815112588849 1.9703405416704107 0.9999895790384453 0.4516776238312032 0.8672765728338405 0.06382318202096471 2.031692075976614 7.1310007806167555 0.066839841797009 0.018474129214046488 8.834559243424474e-10 9.053815112588849 -0.5483119552072422 KGWSMS(ph)EQSEESVGGR ddPTM_PC-9_Lapatinib_30min_R1 1 KGWSMSEQSEESVGGR 16 1 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 KGWS(0.333)MS(0.661)EQS(0.006)EESVGGR 70.72800000000001 0.018515 4004100.0 23540.0 20465.0 23742.0 23384.0 25357.0 21549.0 22597.0 22139.0 30346.0 39706.0 True False 23204.315283292697 20417.614549865855 21790.024406770324 25103.73736673726 23865.5511137801 20627.399503172477 23766.962092029822 23167.658762393054 26928.11392245337 46569.12919508068 0.4982767701343207 0.4384366833301806 0.4679070616822294 0.5390639206839429 0.5124757865625096 0.4429414906334871 0.5103587398525039 0.4974896280611656 0.578239584632343 1.0 15.507086284733575 -9.0377301887097 1.2635564250922693 1.0003685351214051 0.4847650320024322 0.9642298729673331 0.029449321013911553 0.3972203389452677 0.8075604589209795 0.029673417262538873 0.008868756188456435 9.167898812818492e-10 9.0377301887097 -0.515603503118973 down KHAS(ph)FLS(ph)AT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KHASFLSATPR 11 1 H0YAZ7;Q8N412 H0YAZ7 STPG2 Sperm-tail PG-rich repeat-containing protein 2 3 KHAS(1)FLS(1)AT(1)PR 75.509 0.022303 906320.0 0.0 0.0 29795.0 728.0 2157.8 966.99 0.0 500.34 498.53 0.0 True False 0.0 0.0 30505.42579816673 687.2125202078448 1734.9945798969081 916.2793421113947 0.0 487.2066051540507 505.8200581239002 0.0 0.0 KHEAFESDLAAHQDR ddPTM_PC-9_AZD4547_30min_R2 4 KHEAFESDLAAHQDR 15 1 O43707;O43707-2;P12814-4;P12814-3;P12814;P12814-2;H9KV75;P35609-2;P35609;A0A494C1A0;H7C5W8;A0A494C060;F6THM6 O43707;P12814-4 ACTN4;ACTN1;ACTN2 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2 0 ;;; 145.1 4.3493e-05 85391000.0 204717.0 215720.0 362922.0 401353.0 341460.0 406998.0 305554.0 469863.0 338790.0 329205.0 False True 269812.74762187595 285447.27136548 358109.4171509774 308827.2666920367 294054.173028634 381548.3507205449 332747.71406346816 397256.46972761047 356697.74774650723 317679.6331522032 0.8493234046660026 0.8985381547224325 1.1272658986589925 0.9721342965164994 0.9256311778972306 1.2010475677480452 1.0474316869537736 1.2504939828398796 1.1228222099325142 1.0 18.277213074427813 -6.755475413746844 24.999797268707034 1.1352070055991281 0.9620342693220935 0.4437999822966865 0.09446116146373759 137.69198152763255 577178.2393819249 0.031844317464193576 0.031041428158023632 1.7560003019690378e-07 6.755475413746844 -0.17317273627703467 KHEAFESDLAAHQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 KHEAFESDLAAHQDR 15 1 O43707;O43707-2;P12814-4;P12814-3;P12814;P12814-2;H9KV75;P35609-2;P35609;A0A494C1A0;H7C5W8;A0A494C060;F6THM6 O43707;P12814-4 ACTN4;ACTN1;ACTN2 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2 0 ;;;; 126.48 9.3119e-06 78945600.0 138693.0 164084.0 239516.0 235100.0 255850.0 198460.0 241875.0 172087.0 194326.0 164906.0 False True 162170.98558838508 180373.1751266223 245226.96980948775 221928.10920448415 205718.02913459248 188052.408231137 218962.84897664614 167569.89859124803 197167.65012132694 194802.1524048219 0.8324907275735568 0.9259300931736395 1.2588514386631473 1.139248752977284 1.056035709025874 0.9653507721020549 1.1240268460772211 0.8602055804959381 1.0121430779244638 1.0 17.57165009254807 -7.755585562176265 24.999349790516586 0.9521307487646066 1.048123828731951 0.09697307092609875 0.11880963042972947 329.56311206837876 1407452.2951463198 0.06124358586328611 0.03414725435584599 1.75555499087901e-08 7.755585562176265 0.09599307996734441 KHEAFESDLAAHQDR ddPTM_PC-9_Lapatinib_30min_R1 4 KHEAFESDLAAHQDR 15 1 O43707;O43707-2;P12814-4;P12814-3;P12814;P12814-2;H9KV75;P35609-2;P35609;A0A494C1A0;H7C5W8;A0A494C060;F6THM6 O43707;P12814-4 ACTN4;ACTN1;ACTN2 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2 0 ;;; 121.79 2.3929e-05 73447300.0 172251.0 145753.0 189805.0 152478.0 193306.0 190493.0 162772.0 163268.0 199737.0 146560.0 False True 169794.66915303492 145415.51788353763 174199.9655684881 163691.74077169708 181936.1211342184 182346.0584508717 171199.5377104874 170854.027319138 177240.51573614567 171892.70072107535 0.9877945278697736 0.8459667994832347 1.0134227040341677 0.9522902373691499 1.0584284287291534 1.060813272965899 0.9959674668692726 0.9939574315978502 1.0311113560531464 1.0 17.3911487577223 -5.616356280301085 1.8552687701389308 1.0199643110895094 0.9205317531446611 0.3677121431035899 0.04643481954787827 0.3397342252115642 2.332044039505046 0.013494104838760073 0.03259837005302687 2.4190437319762423e-06 5.616356280301085 -0.09943255794484829 KHEEEEAKAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KHEEEEAKAER 11 2 P25789;H0YN18;P25789-2 P25789 PSMA4 Proteasome subunit alpha type-4 0 ; 40.496 0.041406 4894700.0 14728.2 12992.5 11653.6 15760.099999999999 23083.0 22332.0 17196.5 21663.3 25281.0 20156.0 False True 17221.393364790292 14282.309535558834 11931.466020524114 14877.112691933597 18560.05185270197 21160.870606760825 15567.523028121523 21094.661329163664 25650.68679804691 23810.123245191797 0.7232803118004847 0.5998418986950433 0.5011089567935583 0.6248230023310725 0.7795025528248778 0.8887341904470839 0.6538195064263357 0.8859534707962299 1.0773017230486952 1.0 14.53928746780855 -7.41418597382498 0.5877885884970806 1.0379685895168616 0.5987987188516687 0.6706389045421821 0.1015109907186388 0.5160156462313608 0.3651225794421929 0.100990629002366 0.06969975050870539 3.8531332324679524e-08 7.41418597382498 -0.43916987066519286 KHGTDREIS(ph)GK ddPTM_PC-9_Lapatinib_30min_R1 1 KHGTDREISGK 11 2 H0YIV1 H0YIV1 NR2C1 1 KHGTDREIS(1)GK 45.973 0.043263 5755100.0 49216.0 47753.0 35900.0 40549.0 53792.0 57168.0 47689.0 48742.0 59781.0 60755.0 True False 48514.17081489098 47642.4308624356 32948.44057800752 43531.10872749864 50628.06031914105 54723.05790511688 50158.10307593089 51006.73126141926 53047.83425816202 71256.42079905118 0.6808392881773396 0.6686054439471648 0.4623925845352907 0.6109078766425816 0.7105052394073544 0.7679737108805997 0.7039099426194976 0.7158194404019019 0.7444639186658164 1.0 16.12073239845228 -10.503471267247935 0.2009759712927913 1.2653197266551113 0.5673489027061512 0.7063828177521427 0.0690304089821751 11.24354826042356 0.5062067118285201 1.8650937781600812 0.22981972426238412 3.13710267277148e-11 10.503471267247935 -0.69797082394896 KHLEINPDHSIIETLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KHLEINPDHSIIETLR 16 1 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 70.47 0.0041972 2698800.0 41574.0 32858.0 34438.0 46442.0 52350.0 52413.0 49034.0 56414.0 46877.0 35234.0 False True 48611.657076071184 36119.92508904309 35259.1325268423 43840.005306995496 42092.39329761936 49664.370012186824 44389.14454458235 54933.19227557386 47562.48744242885 41621.64528780944 1.1679417461738122 0.8678158885665735 0.8471345205848781 1.0532982298956786 1.0113101730254714 1.1932341854523711 1.0664918274526616 1.3198227003213454 1.1427344381400373 1.0 15.345046374936205 -6.538860602555717 1.7996104528196335 1.1621752825302223 0.9605800445201903 0.2890790986213888 0.11670180785522366 0.3842778401497367 2.5219811623622492 0.044053355982933834 0.047438417611613944 2.891607865751016e-07 6.538860602555717 -0.20159523801003199 KHNGVGGS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KHNGVGGSPPK 11 1 Q96ST3 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 KHNGVGGS(1)PPK 52.966 0.044396 16372000.0 45168.0 39434.0 40477.0 47496.0 48475.0 41039.0 53438.0 40085.0 35847.0 38509.0 True False 52814.05029133547 43348.74690977311 41442.12518987732 44834.95310410959 38976.67173069915 38886.842594969436 48375.96578238351 39032.811223568235 36371.19455913874 45490.376862923746 1.1609939053809153 0.9529212527826706 0.9110086143000082 0.9855920349750202 0.8568113614039216 0.8548366770437459 1.0634329526034685 0.8580454574202779 0.7995360132701503 1.0 15.473273766168884 -4.739480391333934 2.9644734551631613 0.9147354137782816 1.21774337719591 0.4794659917274722 0.07607889713962777 0.4120025640271656 4.71093610125097 0.01948102368650199 0.3163243457656776 1.821879330220168e-05 4.739480391333934 0.3030079634176285 KHPDASVNFSEFSK ddPTM_PC-9_AZD4547_30min_R2 2 KHPDASVNFSEFSK 14 1 Q5T7C4;P09429 Q5T7C4 HMGB1 High mobility group protein B1 0 ; 70.563 0.010757 16767600.0 187491.0 183402.0 265160.0 327160.0 293750.0 277616.0 222422.0 292589.0 236789.0 237734.0 False True 247109.23794493402 242683.10987841518 261643.8051475336 251738.31657161342 252967.88299408738 260256.62763363554 242217.12711149178 247376.09307634717 249305.18312567574 229411.0050205981 1.0771463989826768 1.0578529563419394 1.1405024145377918 1.0973245008407972 1.1026841670972767 1.1344557233000567 1.0558217426829366 1.078309617510006 1.0867184994167625 1.0 17.80757507463023 -9.392844271579973 0.5996616303072517 0.9951973358245263 1.0981689912771964 0.5332444732183452 0.026351263368517112 2.8029257419146942 1.2984972107511144 0.06061156268057342 0.011353926561499953 4.0472098969957487e-10 9.392844271579973 0.10297165545267006 KHPDASVNFSEFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KHPDASVNFSEFSK 14 1 Q5T7C4;P09429 Q5T7C4 HMGB1 High mobility group protein B1 0 55.98 0.028819 6208800.0 44015.0 62275.0 75985.0 82297.0 81786.0 72978.0 83689.0 68782.0 70986.0 56927.0 False True 51465.87016412357 68457.25043886293 77796.77057471736 77686.165900474 65760.62040571353 69150.90520957342 75761.37206410985 66976.54538055316 72024.035957682 67247.41446611591 0.7653211736498179 1.0179908176745833 1.1568737800903406 1.1552290376846814 0.9778906881073989 1.028305783331144 1.12660646755845 0.9959720520452242 1.071030559754426 1.0 16.03719117943254 -4.778774830599023 3.987885198056259 1.0662287991259738 0.7375269912581849 0.6727613754245967 0.06207931972834409 0.13742174202254728 4.105959445873482 0.01607156726987019 0.1311644625089184 1.6642753063769777e-05 4.778774830599023 -0.3287018078677889 KHPDASVNFSEFSK ddPTM_PC-9_Lapatinib_30min_R1 2 KHPDASVNFSEFSK 14 1 Q5T7C4;P09429 Q5T7C4 HMGB1 High mobility group protein B1 0 ; 79.61399999999999 0.007385899999999999 18463500.0 159799.0 178944.0 204898.0 177269.0 221281.0 177914.0 207671.0 196576.0 194825.0 182699.0 False True 157520.23695645237 178529.6661622865 188052.07736915303 190305.95361204824 208265.6866351847 170305.03295779045 218423.18823799284 205709.63859596956 172881.7569017984 214278.27871888535 0.7351199472864226 0.8331673524244707 0.8776068134085637 0.8881252675251945 0.9719402632891753 0.7947843989414157 1.0193435822981631 0.9600116251906377 0.806809527943821 1.0 17.70912608659402 -3.6017597089078692 0.6461865283353632 0.9262181357867562 1.9417481242519319e-19 0.4112935554601319 0.07023369489716362 13.154855984176951 1.2953769697081745 0.029418661763729786 12.721666622621786 0.00025017291622853277 3.6017597089078692 -0.9262181357867562 KHS(ph)EEAEFTPPLK ddPTM_PC-9_AZD4547_30min_R2 1 KHSEEAEFTPPLK 13 1 Q3B726 Q3B726 TWISTNB DNA-directed RNA polymerase I subunit RPA43 1 KHS(0.996)EEAEFT(0.004)PPLK 51.265 0.045668 8018000.0 48581.0 67106.0 62654.0 74842.0 65043.0 67977.0 58280.0 61535.0 56094.0 63844.0 True False 64028.74745242628 88796.70217064659 61823.167022603615 57588.33319737337 56012.90217390457 63726.387443993386 63466.80709667993 52026.17968362804 59059.01432182931 61608.84099260123 1.0392785584152713 1.441298046514305 1.0034788193796427 0.9347413823981742 0.9091698735353796 1.0343708210911882 1.0301574591267157 0.8444596399707633 0.9586126499104546 1.0 15.910849774965808 -5.430915379755228 7.730870947005537 0.9572915597407607 1.2391730738046884 0.5300116527274672 0.10464113817371042 0.1939586190917145 14.489778940482694 0.02577190822094144 0.053845116876253256 3.7075295422111898e-06 5.430915379755228 0.2818815140639277 KHS(ph)EEAEFTPPLK ddPTM_PC-9_Lapatinib_30min_R1 1 KHSEEAEFTPPLK 13 1 Q3B726 Q3B726 TWISTNB DNA-directed RNA polymerase I subunit RPA43 1 KHS(0.997)EEAEFT(0.003)PPLK 57.973 0.030831 10108000.0 40929.0 30814.0 37896.0 40024.0 60168.0 62869.0 57311.0 73549.0 64756.0 56107.0 True False 40345.34495454066 30742.652076206527 34780.337162790325 42967.49847615002 56629.03653483934 60180.239424796986 60278.28315512336 76966.3550438251 57462.497369089535 65805.02019212188 0.613104362505321 0.46717791418422827 0.5285362281061072 0.6529516798369444 0.8605579995189928 0.9145235310178008 0.916013443642098 1.169612209207094 0.8732236112278998 1.0 16.005910029315533 -6.316731663472554 1.3109985828770032 0.9973616024241113 0.5177495010722031 0.8552886485737049 0.08098624836861243 0.14668440154521495 0.5131692536559292 0.03172547701388759 0.042843725177016845 4.82245669609845e-07 6.316731663472554 -0.47961210135190824 KHS(ph)PS(ph)PPPPTPTESR ddPTM_PC-9_AZD4547_30min_R2 1 KHSPSPPPPTPTESR 15 1 Q92922 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 2 KHS(1)PS(1)PPPPTPTESR 71.376 0.038745999999999996 0.0 14464.0 17754.0 15592.0 21770.0 19807.0 21422.0 18186.0 18487.0 17740.0 19474.0 True False 19063.2511301104 23492.63330160733 15385.239892368172 16751.26284314715 17057.13994370689 20082.478953546466 19804.518769049802 15630.258938997833 18677.700183072193 18792.221187424275 1.0144224538431623 1.2501254145161171 0.8187025758649515 0.8913934481761564 0.9076702415104342 1.068659141101725 1.0538679047851436 0.8317408987000205 0.9939059356948864 1.0 14.197847978861608 -5.259932636594252 24.999089615709167 0.9446840036446592 1.1322739272892708 0.37344007439731175 0.09663796019887166 136.69595241372593 2267934.916687492 0.025210250063286543 0.05976122979858885 5.4962611973929165e-06 5.259932636594252 0.18758992364461158 KHS(ph)PS(ph)PPPPTPTESR ddPTM_PC-9_Lapatinib_30min_R1 2 KHSPSPPPPTPTESR 15 1 Q92922 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 2 KHS(1)PS(0.999)PPPPT(0.001)PTESR;KHS(1)PS(0.999)PPPPT(0.001)PT(0.001)ESR 64.83 0.02652 23600500.0 61412.0 53114.0 65424.0 63586.0 71830.0 59531.0 56344.0 53012.0 69127.0 51321.0 True False 60536.2536184185 52991.017796314445 60045.09126394329 68262.32655667778 67605.10062321357 56984.99790353895 59261.21662669067 55475.13104982065 61341.189320419 60191.766469065995 1.0057231606507104 0.8803698729052555 0.9975632015186316 1.1340807981064893 1.1231619304271037 0.9467241326573281 0.9845402469978423 0.9216398571444263 1.0190960146009955 1.0 15.877278536191756 -10.378401966214453 14.863345718711052 0.999999943965677 1.0007875789642184 0.0 0.07554080842935534 0.0 0.0 0.08035362312521575 0.019488616208608145 4.1840612528125294e-11 10.378401966214453 0.0007876349985413977 KHS(ph)PSPPPPTPTESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KHSPSPPPPTPTESR 15 1 Q92922 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 1 KHS(0.83)PS(0.17)PPPPTPTESR;KHS(0.99)PS(0.01)PPPPTPTESR 113.14 0.00011246 9123400.0 11432.9 9302.6 16472.7 13619.6 13599.099999999999 15847.8 17163.8 14536.6 12154.6 10890.0 True False 13368.264159932021 10226.100649258386 16865.471641062635 12856.537967338967 10934.45397695617 15016.71346954256 15537.920608849021 14155.029652800846 12332.338030755935 12864.270794807426 1.0391777639917241 0.7949226825500347 1.3110320755895675 0.9993988911154156 0.8499863032555088 1.1673194469447854 1.2078353181993646 1.1003367294253807 0.9586503757161111 1.0 13.651082060443066 KHS(ph)PSPPPPTPTESR ddPTM_PC-9_Lapatinib_30min_R1 2 KHSPSPPPPTPTESR 15 1 Q92922 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 1 KHS(0.993)PS(0.007)PPPPTPTESR;KHS(0.499)PS(0.499)PPPPT(0.001)PTESR 60.333999999999996 0.023521 7802100.0 32459.0 32507.0 40345.0 29187.0 40499.0 38736.0 32424.0 37360.0 39570.0 27270.3 True False 31996.12870774843 32431.732038724112 37027.9898362037 31333.50934497775 38116.92844409748 37079.35157802633 34102.75606814956 39095.881989385445 35113.209909427285 31983.93501960932 1.000381244150591 1.0140006856204606 1.1577058862051175 0.979663988366885 1.1917523100496556 1.1593117468283067 1.0662464154970674 1.2223599743251041 1.0978389584614718 1.0 14.965059825685891 -4.832444397158321 0.8257253683305166 1.1247381055858225 0.9205353649573377 0.1892080456482833 0.07638177390526935 3.3907333813660365 1.8709242931070307 0.027686927737745805 0.6273046389923035 1.47080671113731e-05 4.832444397158321 -0.20420274062848487 KHSGS(ph)DS(ph)SGRSSSES(ph)PGS(ph)S(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KHSGSDSSGRSSSESPGSSK 20 2 Q8TF01 Q8TF01 PNISR Arginine/serine-rich protein PNISR 5 KHS(0.296)GS(0.737)DS(0.729)S(0.234)GRS(0.096)S(0.219)S(0.21)ES(0.636)PGS(0.922)S(0.922)K 51.486999999999995 0.012675 357610000.0 12911.0 22254.0 9357.9 14206.0 11450.0 9267.9 13781.0 8311.7 10590.0 11763.0 True False 15096.5772961263 24463.230048437672 9581.027826033374 13410.083876473413 9206.45469451274 8781.875008794499 12475.563914200135 8093.526681974104 10744.858715688326 13895.53878414323 1.086433389207882 1.7605096447468211 0.6895038742194495 0.9650639737536634 0.6625475152513413 0.6319924074348133 0.8978107368126318 0.5824550460187956 0.7732595966663578 1.0 13.762334154076543 -5.276140369062062 24.99894009212662 0.7624203012048527 1.423471522104992 0.6218992338446359 0.2019496123298226 393.4920903289254 669130.7128732196 0.04888097012562616 0.10244046942641255 5.294922781272079e-06 5.276140369062062 0.6610512209001393 KHSPS(ph)PPPPTPTESR ddPTM_PC-9_AZD4547_30min_R2 1 KHSPSPPPPTPTESR 15 1 Q92922 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 1 KHS(0.15)PS(0.846)PPPPT(0.003)PT(0.001)ESR 62.94 0.015087 6644800.0 9692.9 6591.7 18324.0 21521.0 15161.0 16500.0 12366.0 15678.0 14928.0 12356.0 True False 12775.040575155355 8722.338117280897 18081.01178731109 16559.665946135512 13056.156847909328 15468.25239163088 13466.550043883735 13255.325344599338 15717.063603883991 11923.420200873692 1.0714241685635855 0.7315298773620144 1.5164282968058276 1.3888352223737026 1.095000983606418 1.2972999467466089 1.1294200671462513 1.1117049572427256 1.318167383108105 1.0 13.541510507889402 -5.249433575952741 24.999477563161108 1.2354582826167415 0.9014770341838947 0.39070116384325315 0.16511384665595458 747.8097187339557 1557144.449027052 0.04149834361441776 0.10800451609606132 5.630752314879026e-06 5.249433575952741 -0.3339812484328468 KHSPS(ph)PPPPTPTESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KHSPSPPPPTPTESR 15 1 Q92922 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 1 KHS(0.251)PS(0.748)PPPPT(0.001)PTESR;KHS(0.268)PS(0.732)PPPPTPTESR 68.26100000000001 0.012906 12047400.0 28279.6 28303.6 31529.5 32888.8 37964.0 35514.2 38766.6 34717.8 33066.0 22098.8 True False 33066.777732440016 31113.39435602408 32281.282856294616 31046.14716292826 30525.22672685428 33651.77283282401 35094.347002121096 33806.49453654976 33549.52769527388 26105.13750599546 1.26667701807147 1.1918494721155326 1.2365873517762818 1.1892734583680327 1.16931874884182 1.2890862124398061 1.3443463760365608 1.2950130804247082 1.2851695451735774 1.0 14.672046137495787 -6.773384011626438 24.988961854468634 1.2675128206787303 1.2099349087810816 0.0 0.09237619744803574 586.9072052559811 1227843.059361048 0.03057238990595745 0.027175669899748754 1.6850624015224426e-07 6.773384011626438 -0.057577911897648715 KHSPS(ph)PPPPTPTESR ddPTM_PC-9_Lapatinib_30min_R1 1 KHSPSPPPPTPTESR 15 1 Q92922 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 1 KHS(0.197)PS(0.803)PPPPTPTESR 72.321 0.0072902 6623100.0 10551.0 10572.0 13250.0 8409.2 14208.0 13479.0 14457.0 9543.0 16819.0 7731.8 True False 10400.540805183566 10547.521183541749 12160.63614647909 9027.64062026886 13372.313374002744 12902.53459108366 15205.51272135572 9986.402618434293 14924.667108078273 9068.231328024092 1.1469205437053815 1.1631288177382637 1.341015210860177 0.9955238561647857 1.474633022723791 1.4228281264958684 1.6767892405176326 1.1012514190691984 1.6458189660375877 1.0 13.146605478953886 -6.279792549200842 24.877907248463696 1.4082415621077802 1.1745649357346872 0.20651871061796878 0.21324681234203818 1138.0526918663054 1542638.2805246993 0.061963569976984385 0.07038593462149897 5.250582065481026e-07 6.279792549200842 -0.23367662637309294 KHT(ph)ILADIVIS(ph)AAGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KHTILADIVISAAGVR 16 1 B8ZZU9 B8ZZU9 MTHFD2 2 KHT(1)ILADIVIS(1)AAGVR 83.37 0.033011 0.0 23995.0 25830.0 16030.0 22805.0 29005.0 28030.0 29302.0 26735.0 22388.0 24995.0 True False 28056.879577147414 28394.231695476996 16412.215994113543 21527.30978480756 23321.678464134668 26560.057456005114 26526.302431891203 26033.234578074014 22715.382146065185 29526.395639688883 0.9502304283775779 0.9616558702922056 0.5558489493398415 0.7290869514689735 0.7898586318739854 0.8995360551324298 0.898392839938614 0.8816936173232258 0.7693245875067647 1.0 14.849717633409684 -6.754643803737481 23.732012891465104 0.8829329864459008 0.7892574247099539 0.1287048602486891 0.11868515446898945 199.63526610248837 697178.8880335499 0.04233475611981231 0.041364909144967724 1.7593660054679243e-07 6.754643803737481 -0.09367556173594693 KIAELEEEQSQGST(ph)TNSDWMK ddPTM_PC-9_Lapatinib_30min_R1 1 KIAELEEEQSQGSTTNSDWMK 21 1 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 KIAELEEEQSQGS(0.008)T(0.508)T(0.337)NS(0.148)DWMK 102.07 6.972699999999999e-05 14532000.0 93001.0 56067.0 54434.0 66178.0 59639.0 51175.0 49901.0 41186.0 65529.0 56019.0 True False 91674.78868570525 55937.18030624622 49958.64664131643 71044.95088333628 56131.15127478534 48986.36454475159 52484.62961253176 43099.651916885145 58148.43396903865 65701.80950937445 1.395316040308219 0.8513796001046974 0.760384638024136 1.0813241128952387 0.8543318927430218 0.7455862313466743 0.7988308085341723 0.6559888112478183 0.8850355021156903 1.0 16.003645484256133 -4.761781857033073 6.764964368941142 0.8364724823861027 1.4088240112778 0.6614778938136876 0.11722370745478726 0.06904039162430417 16.614735651931365 0.02971085429938053 0.18202974833283297 1.730685451671565e-05 4.761781857033073 0.5723515288916974 KIAELEEEQSQGSTTNS(ph)DWMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KIAELEEEQSQGSTTNSDWMK 21 1 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 KIAELEEEQS(0.001)QGS(0.209)T(0.209)T(0.259)NS(0.322)DWMK 76.539 0.0032495 0.0 2793.0 3455.1 8776.2 9244.5 12419.0 9362.4 8357.5 9433.1 10604.0 7726.8 True False 3265.7997357354784 3798.0994940395876 8985.457891923845 8726.560636073384 9985.586100537437 8871.419262436753 7565.817096939824 9185.491120195618 10759.063439202933 9127.607674684852 0.3577936138505467 0.41611116838133866 0.9844263921251506 0.9560621958233634 1.09399817087145 0.9719325784609882 0.8288937656603484 1.0063415790395225 1.1787385942367872 1.0 13.156021067310755 -5.251239006264281 4.828979228575909 0.9991776153987662 0.373420966809745 0.892268862089817 0.0856561481558883 0.05378717841587503 3.7134694922010185 0.023460061166743252 0.059857103310070894 5.6073929817662435e-06 5.251239006264281 -0.6257566485890211 down KICTLPSPPS(ph)PLASLAPVADSSTR ddPTM_PC-9_AZD4547_30min_R2 3 KICTLPSPPSPLASLAPVADSSTR 24 1 Q9UER7-3;Q9UER7;Q9UER7-2 Q9UER7-3 DAXX Death domain-associated protein 6 1 KICTLPS(0.001)PPS(0.996)PLAS(0.002)LAPVADSSTR;KICTLPS(0.002)PPS(0.993)PLAS(0.005)LAPVADSSTR;KICTLPSPPS(0.999)PLAS(0.001)LAPVADSSTR 122.82 2.1571e-09 41367000.0 66415.9 54514.6 88889.0 120608.0 105182.0 85279.0 74405.5 94349.0 73178.4 85496.0 True False 87534.77466346104 72135.37835889391 87710.27378095919 92803.68897502488 90579.29487347808 79946.49064884195 81027.44535744708 79769.5299743337 77046.46082733537 82502.81106295723 1.0609914199973618 0.8743384307699283 1.0631186095468697 1.1248548719656004 1.0978934378897436 0.9690153537657695 0.9821173886501356 0.9668704489773349 0.9338646748477677 1.0 16.332155655726048 -6.802501704527479 23.666957732598487 0.9690367763287225 1.0403278850353943 0.24697429539413818 0.06428771108341273 146.50825325988933 84440.96543374009 0.024760532420445396 0.02183712908491839 1.5757898380410013e-07 6.802501704527479 0.07129110870667177 KICTLPSPPS(ph)PLASLAPVADSSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KICTLPSPPSPLASLAPVADSSTR 24 1 Q9UER7-3;Q9UER7;Q9UER7-2 Q9UER7-3 DAXX Death domain-associated protein 6 1 KICTLPS(0.002)PPS(0.964)PLAS(0.025)LAPVADS(0.003)S(0.003)T(0.003)R;KICTLPS(0.001)PPS(0.999)PLASLAPVADSSTR 77.876 9.305e-05 32184000.0 33556.0 27345.0 40411.0 45122.0 50773.0 50218.0 49705.0 47500.0 50398.0 41607.0 True False 39236.36803878971 30059.63088319081 41374.55149957095 42593.96062749775 40824.395127030155 47584.47967626345 44996.58256696306 46253.175330410166 51134.97540635132 49150.019739169235 0.7982981135513356 0.6115893959496281 0.8418013201040129 0.8666112618781564 0.8306079090848437 0.9681477226008486 0.915494699814003 0.9410611750690615 1.040385653509722 1.0 15.584904375517052 -5.979812452870197 0.4849554974372261 1.0050325937712135 0.6522841418277249 0.711565555720066 0.06255313398005491 0.8738305974232645 0.3470946309594485 0.04935666042013126 0.157073938414955 1.0475808410732218e-06 5.979812452870197 -0.3527484519434886 KICTLPSPPS(ph)PLASLAPVADSSTR ddPTM_PC-9_Lapatinib_30min_R1 2 KICTLPSPPSPLASLAPVADSSTR 24 1 Q9UER7-3;Q9UER7;Q9UER7-2 Q9UER7-3 DAXX Death domain-associated protein 6 1 KICTLPSPPS(1)PLASLAPVADSSTR;KICT(0.001)LPS(0.009)PPS(0.979)PLAS(0.01)LAPVADSSTR 104.65 7.5999e-07 38697000.0 57187.0 44492.0 49951.0 44817.0 48392.0 41201.0 39639.0 34258.0 52302.0 39122.0 True False 56371.502893188626 44388.981507580334 45844.221596436015 48112.99168512928 45545.67770233259 39438.92927422197 41691.31346488343 35849.75174497769 46411.197995523515 45884.185573211755 1.2285606072977704 0.9674135206509069 0.9991290250382242 1.0485746032990233 0.9926225590222355 0.859532075845481 0.9086205398232846 0.781309536109705 1.011485709416611 1.0 15.485709380107417 -6.564428651881656 3.808208692318783 0.8986369997486737 1.0480971466843971 0.37189919719950626 0.08953974043182833 0.23710996327399597 7.3150888271467664 0.02941436588532575 0.030256727578047635 2.7262855902780824e-07 6.564428651881656 0.1494601469357234 KIDAGTMAEPS(ph)ASPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KIDAGTMAEPSASPSK 16 1 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 KIDAGTMAEPS(0.456)AS(0.456)PS(0.088)K 66.673 0.0097939 17729000.0 140230.0 132000.0 127230.0 188860.0 165810.0 167520.0 198400.0 200820.0 173510.0 156870.0 True False 163968.16933125182 145104.08764239118 130263.64572246191 178278.78649238104 133320.72077704407 158734.95629789447 179606.11570838917 195548.68778637846 176047.25550133013 185309.28921776364 0.8848351317054964 0.7830373115935604 0.7029525949418779 0.9620607107443988 0.719449744477591 0.8565947069785547 0.9692234882911215 1.055255721997736 0.9500185136129395 1.0 17.49957567729416 -7.238748467927426 3.224868993376973 1.0027527714743871 0.809952802164776 0.5774762627091663 0.07442951666252498 0.17606042305142885 3.7812347058456917 0.031207119169716933 0.021904196279642768 5.771006082870115e-08 7.238748467927426 -0.19279996930961107 KIDAGTMAEPS(ph)ASPSK ddPTM_PC-9_Lapatinib_30min_R1 1 KIDAGTMAEPSASPSK 16 1 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 KIDAGTMAEPS(0.631)AS(0.278)PS(0.092)K 83.395 0.0020667 13252000.0 122440.0 110290.0 114560.0 108150.0 126240.0 116470.0 101630.0 98098.0 117740.0 95729.0 True False 120693.98314725394 110034.6302811973 105141.31901438825 116103.71177782404 118814.81139738936 111488.84960483084 106891.90412059084 102655.99120435554 104478.88134283457 112275.6300991254 1.0749793436090822 0.9800401937985156 0.9364571717082466 1.034095392520344 1.0582422142052614 0.9929924196942834 0.9520490245854654 0.9143212210318756 0.9305570696917286 1.0 16.7766852930881 -7.22351170979553 3.5279220425578877 0.9409270647043528 1.0121035832534708 0.3547726747576121 0.042146229983775346 0.2745253824124538 7.150461440222106 0.018523268656178524 0.013314662047483663 5.977069286186818e-08 7.22351170979553 0.071176518549118 KIDAGTMAEPSAS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 2 KIDAGTMAEPSASPSK 16 1 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 KIDAGTMAEPS(0.041)AS(0.621)PS(0.338)K;KIDAGTMAEPS(0.248)AS(0.658)PS(0.094)K 130.01 7.0187e-06 12218500.0 94213.0 83064.0 96009.0 127291.0 118708.0 121289.0 116342.0 107746.0 118738.0 127981.0 True False 124170.77424786284 109912.81359494824 94735.85792883378 97946.02657634567 102227.44324923289 113704.77965627382 126696.21261568167 91096.3314567673 125014.24827156878 123500.42414438486 1.0054279174190872 0.8899792397996036 0.7670893325684266 0.7930825116992033 0.8277497341200899 0.920683312984748 1.025876740856862 0.7376195838021268 1.0122576431431045 1.0 16.9141564709832 -6.8128429664328065 7.6346930537917554 0.928714050855529 0.8500674418382533 0.14724553477566216 0.09717416611380535 0.5155260630836314 65.02352882253182 0.03475118091349598 0.030802263086878497 1.5387109116675924e-07 6.8128429664328065 -0.07864660901727571 KIDAGTMAEPSAS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 2 KIDAGTMAEPSASPSK 16 1 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 KIDAGTMAEPS(0.127)AS(0.788)PS(0.085)K;KIDAGTMAEPS(0.28)AS(0.718)PS(0.002)K 125.73 0.00010065 7119700.0 143461.0 114585.0 112755.0 115731.0 121324.0 116074.0 104221.0 110493.0 123577.0 88020.0 True False 141415.21983247457 114319.6854725817 103484.719146887 124242.24380729822 114187.96085216131 111109.78560170977 109617.05342273063 115626.90815452785 109658.4569364997 103234.13972072209 1.369849356182395 1.1073825556337196 1.002427292239203 1.2034995801137982 1.106106576381345 1.0762891607591594 1.06182948508387 1.120045253123935 1.0622305492461819 1.0 16.6555606260199 -4.7651707237779695 5.164120803101655 1.0860169700417426 1.385619632353715 0.7067917298591078 0.055693749706436826 0.08636116189728153 6.44654592774878 0.01344444953530744 0.09318430155212545 1.7172331997370016e-05 4.7651707237779695 0.2996026623119725 KIDAGTMAEPSASPS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 KIDAGTMAEPSASPSK 16 1 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 KIDAGTMAEPS(0.077)AS(0.267)PS(0.657)K 77.74600000000001 0.0038554 12269000.0 78290.0 69687.0 68179.0 76043.0 71670.0 63887.0 57338.0 66989.0 74825.0 69036.0 True False 77173.57024337222 69525.64403305648 62573.58579855086 81635.4558920117 67454.51150864142 61154.701937870916 60306.68108301134 70101.55349536767 66397.42055781893 80968.78061531234 0.9531274851479931 0.8586722376785825 0.772811265317701 1.0082337324538302 0.83309284141405 0.7552874265010939 0.7448139965146825 0.8657849724627134 0.820037303924301 1.0 16.30507813034339 -6.497194391888343 24.821436769170155 0.8198194438973128 0.8907090145162198 0.08789222802836538 0.08775104992111932 1456.1404282931558 1407219.4593119249 0.026782754275495514 0.030246719729547317 3.182772581538874e-07 6.497194391888343 0.070889570618907 KIDTHPSPS(ph)HSSTVK ddPTM_PC-9_AZD4547_30min_R2 1 KIDTHPSPSHSSTVK 15 1 A0A0C4DG98;Q8NI27;Q8NI27-2;H0Y7U4;H7C477;H0Y594 A0A0C4DG98 THOC2 THO complex subunit 2 1 KIDT(0.036)HPS(0.092)PS(0.675)HS(0.139)S(0.026)T(0.032)VK 51.695 0.033234 6702200.0 15832.0 13289.0 47026.0 139440.0 74824.0 65953.0 20471.0 93454.0 35985.0 71949.0 True False 20866.246673942733 17584.409369441237 46402.404513757465 107294.26232652464 64435.979156254034 61828.948483953376 22292.879342418255 79012.8316592798 37887.093635166464 69430.08740957126 0.30053608532640597 0.2532678558462702 0.6683327969908428 1.5453568665928774 0.9280699702442148 0.8905209656329767 0.32108384382280175 1.138020051641005 0.5456869643799923 1.0 16.08327336728177 -5.410423611320419 4.452267651684757 0.904119324223149 0.2867706273506274 0.3940713997967126 0.3091612113392767 0.22822126100226012 7.263506194070043 0.0842729190740893 0.1832275702825073 3.886658549374259e-06 5.410423611320419 -0.6173486968725216 KIDTHPSPS(ph)HSSTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KIDTHPSPSHSSTVK 15 1 A0A0C4DG98;Q8NI27;Q8NI27-2;H0Y7U4;H7C477;H0Y594 A0A0C4DG98 THOC2 THO complex subunit 2 1 KIDT(0.012)HPS(0.039)PS(0.781)HS(0.07)S(0.049)T(0.049)VK 46.318999999999996 0.045394 3915200.0 20010.0 17712.0 66753.0 45201.0 60719.0 60638.0 43335.0 48647.0 50673.0 35458.0 True False 23397.29778448509 19470.330305469928 68344.64468216216 42668.53451361923 48821.547824988535 57458.03653290183 39229.99508176933 47370.06779575711 51413.99676110245 41886.254714626426 0.5585913074322899 0.46483817753872864 1.6316723743337365 1.0186762890194534 1.1655744386222324 1.3717635277817721 0.9365839784207408 1.130921542603707 1.2274670321180325 1.0 15.354189270051382 -5.237187927066606 24.99547455688144 1.1811249099967918 0.511714518530584 0.6638017949229749 0.19173859410634636 435.41008770959706 448766.7155099163 0.0466526909455949 0.12330161693435898 5.791780214039329e-06 5.237187927066606 -0.6694103914662077 KIEISQHAK ddPTM_PC-9_Lapatinib_30min_R1 1 KIEISQHAK 9 1 G5E9R3;M0R0A1;C9J4Z3;Q6P4E4;E9PEL3;M0R2L6;P61513 G5E9R3 RPL37A 60S ribosomal protein L37a 0 50.473 0.045757 4516000.0 48172.0 43902.0 80900.0 64574.0 79962.0 91689.0 70925.0 60623.0 102610.0 52000.0 False True 47485.0584463371 43800.34761633086 74248.71428303077 69322.9873725493 75258.79237134063 87767.6752074984 74597.14946130967 63439.76589514218 91052.98126879796 60988.130714355386 0.77859507891361 0.7181782275222469 1.2174289228634139 1.136663586185829 1.2339908026337691 1.439094364419332 1.2231420866249143 1.0401985624427366 1.4929623223780148 1.0 15.896240877541173 -5.2647334394222725 23.184762862942165 1.229411873283766 0.7483865715601762 0.6288197761562553 0.1457697810878982 56.41762300830103 397098.7907837745 0.036709579612913205 0.08202885356689164 5.435838691672124e-06 5.2647334394222725 -0.4810253017235898 KIESFGS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 KIESFGSPK 9 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 KIES(0.001)FGS(0.999)PK 62.891000000000005 0.027402 32382000.0 256370.0 244270.0 206010.0 242300.0 220500.0 234270.0 244210.0 236480.0 224190.0 226800.0 True False 337890.3271727325 323225.5005398009 203278.17279545736 186441.47849768304 189887.38110705136 219621.05986590078 265944.2169025432 199937.44976979573 236040.22570704366 218859.80103254702 1.5438665555694453 1.4768609813902438 0.9288054354267986 0.8518763044564635 0.8676210990377939 1.0034782944595684 1.2151350574562305 0.9135412205737256 1.0784996815013175 1.0 17.739647466978717 -5.240718092106503 7.496646473381353 0.9794432199536498 1.5136513057260133 0.8106304286834715 0.10208043302437565 0.08312537437700887 22.65294623986737 0.02826741811326812 0.07184158564151664 5.744892518920269e-06 5.240718092106503 0.5342080857723635 KIESFGS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 KIESFGSPK 9 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 KIES(0.007)FGS(0.993)PK 56.413999999999994 0.039811 31099000.0 231880.0 201330.0 160080.0 176000.0 160260.0 166630.0 174090.0 161110.0 162610.0 132820.0 True False 228573.34867841617 200863.83275467835 146918.8403266696 188943.62711878863 150833.8218832827 159503.62333350198 183103.528371088 168595.7587609714 144295.14944078782 155777.76002847496 1.4673041173312207 1.2894256068257883 0.9431310368040596 1.2129050198452667 0.9682628756230123 1.0239178128145248 1.1754150806740198 1.0822838814099869 0.9262885113665249 1.0 17.249129752849875 -5.032959002090637 3.6295671716211357 1.0526500819462878 1.4487472542475255 0.7019988877639207 0.09080234194876229 0.11822787460354353 3.1994525381777192 0.022920925560644307 0.08926530784624849 9.269173213335385e-06 5.032959002090637 0.39609717230123764 KIFPGLS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 2 KIFPGLSPVR 10 1 Q5VZK9-2;Q5VZK9;A0A0U1RR91;Q5VZK9-3 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 KIFPGLS(1)PVR;KIFPGLS(1)PVR 104.94 0.0011611 7787200.0 63493.0 50866.0 60083.0 51705.0 56716.0 53126.0 48174.0 46406.0 49105.0 41598.0 True False 62587.578176809846 50748.22290219772 55143.20766708707 55507.558182823734 53380.07638794622 50853.92482275472 50668.2140028077 48562.19217343202 43574.27780142601 48788.15887414915 1.2828436165885415 1.0401749947790533 1.130258016280774 1.1377260274569394 1.0941195080888806 1.0423415434457015 1.0385350702310414 0.9953684109847224 0.8931322437033843 1.0 15.574243420647937 -7.027301421454477 0.7094287396670014 0.9489694983992603 1.1541781423158137 0.6141397175658256 0.06158476112220221 0.4894118769333828 0.5137343044136321 0.047880308781420695 0.0375848845219648 9.390713232472158e-08 7.027301421454477 0.20520864391655347 KIHSQEEALR ddPTM_PC-9_Lapatinib_30min_R1 1 KIHSQEEALR 10 1 F2Z2Y4;O00764-3;O00764-2;O00764 F2Z2Y4 PDXK Pyridoxal kinase 0 75.652 0.0096076 1111800.0 6135.0 6900.9 7880.6 5829.6 7351.6 6523.9 6083.3 5798.0 7552.0 4797.8 False True 6047.513774978788 6884.921390040028 7232.68748799571 6258.328230975515 6919.193341801708 6244.888004953686 6398.263508184497 6067.396246639636 6701.414233914449 5627.09333733335 1.0747136065535166 1.2235306893456928 1.285332773851454 1.1121777898109833 1.2296212141881189 1.1097893051678267 1.1370459177804577 1.0782469532511687 1.1909193312030992 1.0 12.45817417842741 -10.14174802318077 0.2451094493299725 0.9126367943636055 1.1996219299157798 0.3495774974247845 0.06646739250663503 12.802361446918402 0.8921814118157192 0.9716665547871742 0.12276263492239761 7.215259857455617e-11 10.14174802318077 0.2869851355521743 KIIPTLEEGLQLPS(ph)PTATSQLPLESDAVECLNYQHYK ddPTM_PC-9_AZD4547_30min_R2 1 KIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYK 37 1 P61978;P61978-2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 KIIPTLEEGLQLPS(0.775)PT(0.177)AT(0.039)S(0.009)QLPLESDAVECLNYQHYK 102.8 3.6256000000000003e-19 3394800.0 13549.0 8037.5 16169.0 27084.0 21033.0 16018.0 14087.0 17943.0 14529.0 18654.0 True False 17857.30016329271 10635.464693120928 15954.588495363081 20840.20224362873 18112.931006007315 15016.39192782686 15340.715709864979 15170.321639121436 15296.97327845863 18000.929137835716 0.9920210243902847 0.5908286517703413 0.8863202767588546 1.1577292529764598 1.006222004837305 0.8342009355652799 0.8522179934379444 0.8427521447898656 0.8497879837939195 1.0 14.135783754323986 -5.507551665094782 24.98430161210826 0.9310835946919337 0.7782122304830924 0.15531621477222723 0.1313802747888617 1161.0778723905194 1892642.4227650615 0.03578143930390503 0.07081289361272804 3.107766170699599e-06 5.507551665094782 -0.1528713642088413 KIIPTLEEGLQLPSPTATSQLPLES(ph)DAVECLNYQHYK ddPTM_PC-9_Lapatinib_30min_R1 1 KIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYK 37 1 P61978;P61978-2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 KIIPTLEEGLQLPS(0.039)PT(0.127)AT(0.127)S(0.127)QLPLES(0.559)DAVECLNY(0.02)QHY(0.002)K 68.35300000000001 1.3835e-06 1092500.0 11494.0 7643.5 10132.0 7424.2 8867.9 11482.0 6808.8 7707.9 10703.0 8828.7 True False 11330.09345225855 7625.801945365236 9298.986070651034 7970.2004344051775 8346.307556962203 10990.941625849293 7161.326348285737 8066.037173072377 9497.51543241345 10354.729031496712 1.0941950694986806 0.7364559634703424 0.8980424347528215 0.7697159829254493 0.8060382392986479 1.0614417424557772 0.6915995895694251 0.7789713423245882 0.9172152553219098 1.0 13.338002180328457 -4.745629043758044 24.97099224230776 0.8432578495903597 1.0941957760623684 0.29478477988460006 0.1122393498573933 1102.0951235563919 1740562.961656548 0.026795788774412632 0.6655567332405689 1.7962672683723823e-05 4.745629043758044 0.25093792647200874 KINS(ph)APPTETK ddPTM_PC-9_AZD4547_30min_R2 1 KINSAPPTETK 11 1 Q9NRL2;Q9NRL2-2 Q9NRL2 BAZ1A Bromodomain adjacent to zinc finger domain protein 1A 1 KINS(0.99)APPT(0.005)ET(0.005)K 71.529 0.013524000000000001 3090700.0 29343.0 25692.0 30277.0 36884.0 31925.0 27997.0 26448.0 26613.0 27215.0 27549.0 True False 38673.46362768454 33996.4365655568 29875.50719735965 28380.963652119408 27492.764815612787 26246.343164150872 28801.820763435 22500.572355901408 28653.529339476318 26584.517895262994 1.4547363160787519 1.2788058335116363 1.1237934543354298 1.067574885650889 1.0341645059702824 0.9872792603407572 1.0834057956931054 0.8463788000425131 1.077827683479714 1.0 14.69829868323107 -4.228020575041211 0.6503423644781228 0.9881467499301925 2.1897335117220194 0.8512839850513048 0.06113850603787636 2.0612239831167556 0.3930557966849456 0.025449752940539937 2.1620917745757215 5.9153360914361474e-05 4.228020575041211 1.2015867617918268 KINS(ph)APPTETK ddPTM_PC-9_Lapatinib_30min_R1 1 KINSAPPTETK 11 1 Q9NRL2;Q9NRL2-2 Q9NRL2 BAZ1A Bromodomain adjacent to zinc finger domain protein 1A 1 KINS(0.871)APPT(0.007)ET(0.123)K 55.176 0.0394 3971200.0 52055.0 36475.0 38482.0 31151.0 31680.0 29838.0 30756.0 22762.0 29170.0 19327.0 True False 51312.686154282135 36390.54437851734 35318.15850481574 33441.948456689686 29816.644685276406 28561.89829577524 32348.39518973624 23819.605616766352 25884.567426282392 22667.64619839128 2.263697152548807 1.6053958165757842 1.5580867195343056 1.4753163237152984 1.3153833628915774 1.260029296636996 1.4270734114436636 1.0508195428979663 1.1419168624627385 1.0 14.468346969383667 -1.5228787452803376 0.3680388590680513 1.122035537437363 14.794686829875658 0.8792366424245517 0.12007410793482404 21.556301490542193 0.2984531145665048 0.09567848264148876 207.99353940125079 0.029999999999999995 1.5228787452803376 13.672651292438296 up KIPEPS(ph)PVTR ddPTM_PC-9_AZD4547_30min_R2 1 KIPEPSPVTR 10 1 H0YHT2;A0A1B0GV47;Q7Z4S6-6;Q7Z4S6-3;Q7Z4S6-5;Q7Z4S6-2;Q7Z4S6;Q7Z4S6-4;H0YI78 H0YHT2 KIF21A Kinesin-like protein KIF21A 1 KIPEPS(0.989)PVT(0.011)R 56.286 0.03955 60101000.0 19413.0 19699.0 27076.0 29947.0 30017.0 26349.0 25141.0 26881.0 28297.0 31923.0 True False 25585.930184515582 26066.316515059283 26716.954548855876 23043.181826537795 25849.657681135428 24701.392864671634 27378.50029542949 22727.159113928752 29792.721650529547 30805.38548660496 0.8305667914995272 0.84616102357796 0.8672819419991726 0.7480244594425742 0.8391278756234224 0.8018530680426801 0.888756945026201 0.7377657755268524 0.9671270519722681 1.0 14.910894968639266 -8.400612824925167 5.871165960443493 0.9981366370645984 0.8226501006898809 0.6769843679192156 0.045386744859304606 0.12051988160036106 4.917919744198707 0.04115934297741854 0.010680440952859568 3.975458050346672e-09 8.400612824925167 -0.17548653637471756 KIPEPS(ph)PVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 KIPEPSPVTR 10 1 H0YHT2;A0A1B0GV47;Q7Z4S6-6;Q7Z4S6-3;Q7Z4S6-5;Q7Z4S6-2;Q7Z4S6;Q7Z4S6-4;H0YI78 H0YHT2 KIF21A Kinesin-like protein KIF21A 1 KIPEPS(0.984)PVT(0.016)R;KIPEPS(0.971)PVT(0.029)R;KIPEPS(0.994)PVT(0.006)R;KIPEPS(0.982)PVT(0.018)R 70.438 0.0164 116785500.0 206976.0 236589.0 287963.0 331837.0 378948.0 267820.0 309502.0 297756.0 287555.0 238190.0 True False 242012.94883766092 260075.9923577708 294829.130025759 313245.2487200693 304695.8597009798 253775.04772983523 280183.7299595661 289940.22049856005 291759.9478743872 281371.9614889973 0.8601175026713689 0.924313819264258 1.047826970624747 1.1132781214674028 1.082893469870112 0.9019201713876485 0.9957770080460642 1.030451715814967 1.0369190530940524 1.0 18.102119046663823 -5.075920654542648 3.476832081297538 1.026533397478026 0.8684404792003644 0.5139600574689918 0.05364542321114464 0.2062825515172998 4.654362895300487 0.015470146000700053 0.056340743789032595 8.396133695907346e-06 5.075920654542648 -0.1580929182776616 KIPEPS(ph)PVTR ddPTM_PC-9_Lapatinib_30min_R1 3 KIPEPSPVTR 10 1 H0YHT2;A0A1B0GV47;Q7Z4S6-6;Q7Z4S6-3;Q7Z4S6-5;Q7Z4S6-2;Q7Z4S6;Q7Z4S6-4;H0YI78 H0YHT2 KIF21A Kinesin-like protein KIF21A 1 KIPEPS(0.775)PVT(0.225)R;KIPEPS(0.997)PVT(0.003)R;KIPEPS(0.859)PVT(0.141)R 68.033 0.019274 162602000.0 332132.0 318747.0 323889.0 325210.0 288129.0 302914.0 294688.0 328799.0 306061.0 237587.0 True False 327395.73677445005 318008.9609052566 297260.09666769527 349127.0282687578 271181.8187034091 289959.0743470222 309945.50272054196 344076.20187976235 271589.1872147894 278653.5963852224 1.1749201913110947 1.141234008929236 1.066772869698586 1.2529069525666914 0.9731861430150573 1.0405717999281467 1.1122967969595494 1.2347811273323637 0.9746480603083016 1.0 18.08811324781925 -14.522843676899189 0.01778240273526762 5.304588664267842e-07 1.9082658779454624 0.18125461340261273 0.08836006463890714 8247.48794372847 11.072230380823022 775.584636606293 452.7425732412502 3.0002422535756095e-15 14.522843676899189 1.908265347486596 KIQALQQQADEAEDR ddPTM_PC-9_AZD4547_30min_R2 2 KIQALQQQADEAEDR 15 1 A0A2R8YGX3;A0A2R8Y5V9;P67936;A0A590UJB9;A0A590UK79 A0A2R8YGX3 TPM4 Tropomyosin alpha-4 chain 0 ; 137.39 2.8973e-06 0.0 37037.0 36970.0 49342.0 72808.0 63364.0 51691.0 41475.0 54482.0 50009.0 53131.0 False True 48813.9955825428 48919.82951224642 48687.69284050992 56023.24047238665 54567.00234225491 48458.753598532836 45166.19465227866 46063.05877181151 52652.37364460303 51270.899861817794 0.9520799462093177 0.9541441567066731 0.9496165070581952 1.092690797769828 1.0642879779625591 0.9451512208511245 0.8809323568341464 0.8984250109898181 1.0269445979397378 1.0 15.645852598423517 -6.961128946637364 24.556166720605546 0.9388152792812535 1.0022175128989803 0.14674498260773827 0.06010158087266415 231.31385676845775 146127.8972038643 0.022789625904656417 0.020098524621906977 1.0936316072401427e-07 6.961128946637364 0.06340223361772679 KIQALQQQADEAEDR ddPTM_PC-9_Lapatinib_30min_R1 1 KIQALQQQADEAEDR 15 1 A0A2R8YGX3;A0A2R8Y5V9;P67936;A0A590UJB9;A0A590UK79 A0A2R8YGX3 TPM4 Tropomyosin alpha-4 chain 0 104.09 0.005998699999999999 0.0 25400.0 23675.0 28079.0 24568.0 27284.0 27667.0 23122.0 24762.0 29560.0 22662.0 False True 25037.791342210476 23620.18199208767 25770.453008074463 26374.81267644547 25679.208762407867 26483.746904927033 24319.14402318511 25912.53291812532 26230.641519400302 26579.0965047831 0.9420106261965956 0.8886751281345115 0.9695759599441945 0.9923141169113529 0.966143027389464 0.9964126094414493 0.9149725619457645 0.97492151072412 0.9868898859929234 1.0 14.698004443899322 -5.323428830216788 8.565195823105494 0.9732478110764212 0.9154458168140864 0.4600594081269249 0.025856105532583645 0.2910350395248842 38.01051123159432 0.006643218850498166 0.013902857713970432 4.748661030023174e-06 5.323428830216788 -0.05780199426233479 KIQSSLSS(ph)ASPSK ddPTM_PC-9_Lapatinib_30min_R1 1 KIQSSLSSASPSK 13 1 Q5W0B1 Q5W0B1 RNF219 RING finger protein 219 1 KIQSSLS(0.004)S(0.427)AS(0.427)PS(0.142)K 75.548 0.0083603 16620000.0 95015.0 66948.0 73056.0 71711.0 67171.0 57199.0 53439.0 53842.0 62586.0 50457.0 True False 93660.06867638283 66792.98601927301 67049.61768431513 76984.86616088325 63220.13384326714 54752.73210738141 56205.809940964864 56343.69587988462 55536.90562020257 59178.42522027361 1.5826725420245948 1.1286712306158289 1.1330078053740602 1.3008941328589025 1.0682969951962984 0.9252144156182104 0.9497685977914402 0.9520986013088794 0.9384654190016616 1.0 15.85278368545725 -1.5228787452805108 0.37973136235406707 0.9413420787913583 8.816055245965691 0.7478506986958616 0.09882073332554497 36.67637795534241 0.5008479407612898 0.0806349727319941 212.47393121193446 0.029999999999988033 1.5228787452805108 7.874713167174333 KIQSSLSSAS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 1 KIQSSLSSASPSK 13 1 Q5W0B1 Q5W0B1 RNF219 RING finger protein 219 1 KIQSSLSS(0.002)AS(0.859)PS(0.139)K 126.42 0.00060391 0.0 92155.0 85286.0 96685.0 142380.0 144440.0 123160.0 97326.0 107180.0 96623.0 115070.0 True False 121458.37305692244 112853.03164136986 95402.89372714314 109556.49074907179 124386.99921588456 115458.7857305006 105987.82545455496 90617.79375138137 101730.29452023593 111041.43432458206 1.0938112768058357 1.0163146065953397 0.8591648181369276 0.9866271218077959 1.1201854512459957 1.039781109031844 0.9544889806155147 0.8160718951675198 0.9161471583919836 1.0 16.76073858290868 -7.52250586684959 24.99098658213895 0.8967217881162388 1.0135089735947578 0.279561964858019 0.07785840933030036 17.897816647817066 1199843.371788851 0.038273130100072834 0.022410948403576894 3.002576859015484e-08 7.52250586684959 0.11678718547851896 KIQSSLSSASPS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 KIQSSLSSASPSK 13 1 Q5W0B1 Q5W0B1 RNF219 RING finger protein 219 1 KIQSSLSS(0.001)AS(0.027)PS(0.972)K 86.22200000000001 0.0035310000000000003 17700000.0 130030.0 101750.0 97298.0 97128.0 115950.0 95085.0 66879.0 89971.0 95314.0 74385.0 True False 128175.7483554183 101514.40412650126 89298.53402114131 104271.11712950951 109130.04896647089 91018.43620396106 70341.6673785397 94151.38111528367 84578.73361908385 87242.34813821796 1.4691918671463267 1.1635909199242562 1.0235686673594082 1.19518925561601 1.2508839032344277 1.043282742226982 0.8062789331059438 1.079193569688424 0.9694687892293529 1.0 16.412740980359985 -6.9107091899051625 4.890408113416198 0.9644852364644797 1.2037932165100245 0.5020527586731349 0.12119494289788012 0.19558220422059924 8.048829377449149 0.044814610592602465 0.03928579977680108 1.2282614181096348e-07 6.9107091899051625 0.23930798004554477 KIQVLQQQADDAEER ddPTM_PC-9_AZD4547_30min_R2 1 KIQVLQQQADDAEER 15 1 A0A087WWU8;P06753-5;P06753-2;P06753-4;P06753-3;P06753-6;D6R904;Q5VU61 A0A087WWU8 TPM3 Tropomyosin alpha-3 chain 0 116.58 8.994e-05 9598400.0 42269.0 38380.0 53665.0 62225.0 59531.0 56374.0 44178.0 66500.0 42210.0 53561.0 False True 55709.66275018227 50785.584438193604 52953.36703591188 47879.98761666659 51266.14822985888 52848.92486823025 48109.756415873846 56223.95301797777 44441.134426577104 51685.84569269962 1.0778514311520881 0.9825820542850636 1.0245235678399915 0.9263655644011144 0.9918798375606337 1.02250285663208 0.9308110522542754 1.0878017427103672 0.8598318133518361 1.0 15.657481628275773 KIQVLQQQADDAEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KIQVLQQQADDAEER 15 1 A0A087WWU8;P06753-5;P06753-2;P06753-4;P06753-3;P06753-6;D6R904;Q5VU61 A0A087WWU8 TPM3 Tropomyosin alpha-3 chain 0 147.56 7.8017e-05 6400800.0 51916.0 45673.0 54974.0 62890.0 68887.0 58829.0 55873.0 56438.0 48373.0 42594.0 False True 60704.353412260265 50207.11359765856 56284.78865005596 59366.47719213102 55389.086859467134 55743.90367746431 50580.304954510124 54956.562301003934 49080.363612274916 50315.955026081494 1.2064633053430844 0.9978368406528999 1.1186270561868596 1.1798738026806437 1.1008255101340312 1.1078772856158492 1.0052537992827841 1.0922293390340492 0.9754433476783636 1.0 15.618728326043772 -7.442354286709084 1.0781862016894275 1.0058795299060062 1.1188635630889796 0.4031025681248186 0.05907461518889011 0.5931554079760514 1.295347841350124 0.044887993214216375 0.022056907724834467 3.611151536268186e-08 7.442354286709084 0.11298403318297345 KIQVLQQQADDAEER ddPTM_PC-9_Lapatinib_30min_R1 1 KIQVLQQQADDAEER 15 1 A0A087WWU8;P06753-5;P06753-2;P06753-4;P06753-3;P06753-6;D6R904;Q5VU61 A0A087WWU8 TPM3 Tropomyosin alpha-3 chain 0 188.63 1.5807e-07 5553600.0 44407.0 49373.0 55161.0 42821.0 45429.0 44255.0 39314.0 40208.0 48272.0 35640.0 False True 43773.74803675358 49258.67985196805 50625.87550761762 45970.1991866685 42756.95553685043 42362.3168134437 41349.48655512061 42076.21046652058 42835.09903330488 41800.326512685104 1.0472106724685417 1.1784281119674884 1.211135886516442 1.099756940241076 1.022885683055012 1.0134446390170673 0.9892144393315282 1.0066000430343947 1.0247551300898512 1.0 15.351226591147277 -6.1695182915471065 3.0408473989480136 1.0076531613229145 1.1495393008343164 0.702752075282838 0.04038061549084243 0.14193852187382577 2.539432724927643 0.012813227545191692 0.017016422559008357 6.768332855608872e-07 6.1695182915471065 0.14188613951140194 KIS(ph)ENSYSLDDLEIGPGQLSSSTFDSEK ddPTM_PC-9_AZD4547_30min_R2 2 KISENSYSLDDLEIGPGQLSSSTFDSEK 28 1 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VRN8 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 KIS(0.287)ENS(0.269)Y(0.174)S(0.269)LDDLEIGPGQLSSSTFDSEK;KIS(0.325)ENS(0.325)Y(0.024)S(0.325)LDDLEIGPGQLSSSTFDSEK 96.77 6.264400000000001e-10 35884000.0 127254.0 135797.0 144288.0 126424.0 149204.0 187302.0 178828.0 172970.0 173239.0 156782.0 True False 167718.12495236954 179690.72459492923 142374.64684389552 97278.90003132928 128489.60004851027 175589.976330742 194743.34556426 146241.46095518235 182396.05986557194 151293.10990072685 1.1085641974206242 1.187699325586181 0.941051756668342 0.6429830155197432 0.8492759527041289 1.160594665850665 1.287192428604605 0.9666101850318286 1.205580743136642 1.0 17.206986761142836 -6.773732838389799 24.989805143856444 1.1321085781234528 0.9422475993780595 0.23194743555670838 0.16162155282649962 369.50753121196544 751120.352288855 0.06286957927416867 0.05584027023326536 1.683709497233145e-07 6.773732838389799 -0.18986097874539332 KIS(ph)ENSYSLDDLEIGPGQLSSSTFDSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KISENSYSLDDLEIGPGQLSSSTFDSEK 28 1 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VRN8 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 KIS(0.941)ENS(0.029)Y(0.001)S(0.029)LDDLEIGPGQLSSSTFDSEK 118.53 1.1866e-12 8324100.0 23786.0 36376.0 30488.0 43268.0 76569.0 72119.0 114710.0 110580.0 89568.0 94006.0 True False 27812.500005085607 39987.16887939107 31214.949546383865 40843.83423674866 61565.85410516551 68336.9526817565 103843.8383715184 107677.39216919467 90877.76255399152 111048.5436489137 0.2504535322229566 0.36008728764433673 0.2810928313033236 0.3678016198562565 0.5544048763017502 0.6153790985121577 0.935121118740887 0.969642542180678 0.8183606877484746 1.0 16.76083094715721 -6.8142380158342455 1.1069441356386922 0.950379840899154 0.29709925577998064 0.9462693315249281 0.0652329855365715 0.100216447997547 0.2599074564458921 0.03535927367657604 0.03032863139980814 1.5337761637620695e-07 6.8142380158342455 -0.6532805851191733 down KIS(ph)ENSYSLDDLEIGPGQLSSSTFDSEK ddPTM_PC-9_Lapatinib_30min_R1 2 KISENSYSLDDLEIGPGQLSSSTFDSEK 28 1 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VRN8 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 KIS(0.518)ENS(0.261)Y(0.101)S(0.121)LDDLEIGPGQLSSSTFDSEK;KIS(0.259)ENS(0.259)Y(0.223)S(0.259)LDDLEIGPGQLSSSTFDSEK 94.595 7.6599e-10 17133300.0 31055.0 34042.0 43842.0 47893.0 94784.0 122031.0 136160.0 142720.0 120287.0 141772.0 True False 30612.150005210493 33963.17784053425 40237.479995014095 51415.210986364495 89208.99147251381 116812.01859815496 143209.69856400345 149351.29222497554 106739.01138173555 166277.1013006842 0.18410322146435282 0.20425649457959666 0.24199050669190683 0.30921402035622886 0.5365079783968228 0.7025141627103545 0.8612713202465129 0.8982072158865628 0.6419345210301446 1.0 17.34322997730979 -6.504904507452155 1.2271174987763422 0.8497090476784802 0.19497614522689102 0.9171194439719396 0.08433547924548922 0.11564249800236584 0.36360403351556053 0.03644436581950551 0.04184722723938365 3.1267668041449784e-07 6.504904507452155 -0.6547329024515892 down KIS(ph)ENSYSLDDLEIGPGQLSSSTFDSEKNESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KISENSYSLDDLEIGPGQLSSSTFDSEKNESR 32 2 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VRN8 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 KIS(0.257)ENS(0.257)Y(0.23)S(0.257)LDDLEIGPGQLSSSTFDSEKNESR 46.63 0.004721100000000001 10181000.0 14988.0 19974.0 16494.0 21693.0 30549.0 38963.0 50719.0 54342.0 47335.0 38688.0 True False 17525.172373506382 21956.88671643272 16887.279513843343 20477.611539654914 24563.142747831404 36919.71168955859 45914.52914623881 52915.58008010837 48027.18482597799 45701.82814596051 0.3834676441724661 0.48043782069959584 0.3695099342614804 0.4480698556358491 0.5374652118812995 0.8078388368107732 1.004654102667381 1.1578438374742666 1.0508810429331372 1.0 15.479964256087921 -6.911053605264153 1.5869141370614201 1.0818205394546534 0.4173984314695314 0.9730401300185723 0.04840049553630026 0.05329679529159113 0.27539462171917956 0.02228486388619371 0.017939097535995808 1.2272877368465288e-07 6.911053605264153 -0.664422107985122 down KIS(ph)GTTALQEALK ddPTM_PC-9_AZD4547_30min_R2 2 KISGTTALQEALK 13 1 J3KP58;P30622-2;P30622-1;P30622;F5H0N7;Q9UDT6-2;Q9UDT6 J3KP58;Q9UDT6-2 CLIP1;CLIP2 CAP-Gly domain-containing linker protein 1;CAP-Gly domain-containing linker protein 2 1 KIS(0.748)GT(0.21)T(0.041)ALQEALK;KIS(0.604)GT(0.366)T(0.03)ALQEALK 91.51799999999999 0.0023261999999999996 170557000.0 184070.0 148945.0 137415.0 142058.0 141387.0 122145.0 126431.0 136969.0 149379.0 136135.0 True False 242600.43110615495 197088.55847177538 135592.78731463407 109308.7228742214 121757.8555672684 114507.25384095489 137683.11407069908 115803.58828450207 157274.86897672724 131368.9550862694 1.8467105180736223 1.5002673831298134 1.0321524383412422 0.8320742355181167 0.9268388828038602 0.871646225440086 1.048064316110935 0.8815141157852279 1.1971996646654117 1.0 17.003264854854862 -5.087077853368424 2.218617936640677 0.9547268641042569 1.8616878435165556 0.8929412977792766 0.10054771836211059 0.10572215587814757 0.8914745679775691 0.027184747542055528 0.14578047431271526 8.183180800085853e-06 5.087077853368424 0.9069609794122987 KIS(ph)GTTALQEALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KISGTTALQEALK 13 1 J3KP58;P30622-2;P30622-1;P30622;F5H0N7;Q9UDT6-2;Q9UDT6 J3KP58;Q9UDT6-2 CLIP1;CLIP2 CAP-Gly domain-containing linker protein 1;CAP-Gly domain-containing linker protein 2 1 KIS(0.851)GT(0.074)T(0.074)ALQEALK 86.49799999999999 0.011114 18377000.0 28246.0 31255.0 28259.0 26583.0 28998.0 21597.0 19299.0 20930.0 20304.0 13773.0 True False 33027.48991607028 34357.78984290103 28932.801732854285 25093.640693248806 23316.050063884744 20464.415300654397 17470.85900733971 20380.609677168097 20600.907588605838 16269.935872991995 2.029970503503688 2.1117348040648873 1.778298449281695 1.5423318745161199 1.4330757198981503 1.2578055291923562 1.0738124073581163 1.2526545793582258 1.2661947625007688 1.0 13.98992094427232 -5.829208736072659 0.8242946947050187 1.1549481713805771 2.1826397111164195 0.9404682702098212 0.08926512417811182 0.17870259494839155 0.22533494433558174 0.04171945476357749 0.12815016938913218 1.481805709878784e-06 5.829208736072659 1.0276915397358424 up KIS(ph)GTTALQEALK ddPTM_PC-9_Lapatinib_30min_R1 2 KISGTTALQEALK 13 1 J3KP58;P30622-2;P30622-1;P30622;F5H0N7;Q9UDT6-2;Q9UDT6 J3KP58;Q9UDT6-2 CLIP1;CLIP2 CAP-Gly domain-containing linker protein 1;CAP-Gly domain-containing linker protein 2 1 KIS(0.951)GT(0.024)T(0.024)ALQEALK;KIS(0.998)GT(0.002)TALQEALK 147.64 0.00016299999999999998 47911000.0 47859.0 49622.0 60677.0 53525.0 60832.0 51851.0 47973.0 49711.0 46342.0 60950.0 True False 47176.52188373432 49507.10330776658 55688.37127999337 57461.40705416576 57253.98136031358 49633.453600584544 50456.80720630823 52020.754538927715 41122.47595710588 71485.12628922988 0.6599487800141446 0.6925511064701781 0.7790203944618828 0.8038232571860621 0.8009215949156069 0.6943186111159243 0.7058364421454505 0.7277143825479299 0.5752591915515926 1.0 16.125355475132928 -5.069913752372144 4.567776718209971 0.7495524522516791 0.666009994480964 0.09382812779606275 0.10250673070179366 0.5183555503426411 20.381052453772664 0.02530039356888866 0.07844015879935584 8.513070846202272e-06 5.069913752372144 -0.08354245777071512 KIS(ph)TEDINK ddPTM_PC-9_AZD4547_30min_R2 2 KISTEDINK 9 1 E5RGN0;A0A087WZU2;Q00536;Q00536-3;Q00536-2;E5RJM2;E5RIY8;E5RIU4 E5RGN0 CDK16 Cyclin-dependent kinase 16 1 KIS(0.882)T(0.118)EDINK;KIS(0.892)T(0.108)EDINK 87.719 0.0048928 13912700.0 92811.0 66200.0 70428.0 84327.0 66139.0 82063.0 71294.0 67513.0 71919.0 69533.0 True False 122322.9674112745 87597.85538844224 69494.07870316229 64886.71298916256 56956.74149224157 76931.58763723646 77639.02788522145 57080.41714440209 75720.49151445142 67098.6708341979 1.8230311553195577 1.3055080570060504 1.035699781220458 0.9670342524295135 0.8488505179630573 1.1465441368777018 1.157087419467205 0.850693708753917 1.1284946567951877 1.0 16.03399656773491 -4.784785008160516 1.8852433333979737 1.0108220625133864 2.078698205074123 0.8494861563881179 0.10420025482086344 0.29459206995942544 1.1117118270991981 0.02892902819221443 0.5607893343382075 1.641402126902806e-05 4.784785008160516 1.0678761425607368 KIS(ph)TEDINK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KISTEDINK 9 1 E5RGN0;A0A087WZU2;Q00536;Q00536-3;Q00536-2;E5RJM2;E5RIY8;E5RIU4 E5RGN0 CDK16 Cyclin-dependent kinase 16 1 KIS(0.791)T(0.209)EDINK 62.338 0.028461 4820100.0 24277.0 38391.0 28067.0 38346.0 28237.0 22129.0 27607.0 28476.0 21119.0 23584.0 True False 28386.616607393564 42202.204762719986 28736.22372469024 36197.597939409345 22704.162551000547 20968.516284121913 24991.86510262849 27728.535172815973 21427.82542177732 27859.592509158734 1.0189171502799825 1.5148177328453807 1.0314660458599068 1.2992866973021777 0.8149495561909831 0.7526497839919444 0.8970649909689996 0.9952957913401039 0.7691363545512379 1.0 14.765886535933868 -6.263711729898121 24.994478262456823 0.8666149914031804 1.22426762534351 0.5532368315058886 0.15159996716418672 143.94640314386177 1583320.2707272086 0.04396831563198499 0.052276813891926996 5.448641954061465e-07 6.263711729898121 0.35765263394032965 KIS(ph)TEDINK ddPTM_PC-9_Lapatinib_30min_R1 2 KISTEDINK 9 1 E5RGN0;A0A087WZU2;Q00536;Q00536-3;Q00536-2;E5RJM2;E5RIY8;E5RIU4 E5RGN0 CDK16 Cyclin-dependent kinase 16 1 KIS(0.88)T(0.12)EDINK;KIS(0.871)T(0.129)EDINK 88.803 0.0045092 18730800.0 123814.0 87812.0 106377.0 89090.0 97823.0 81997.0 83862.0 84089.0 82581.0 94186.0 True False 122048.38965529298 87608.67670915328 97631.09368709484 95641.97579552756 92069.24346741768 78490.17945434278 88203.96402008247 87996.08192198706 73279.8581635181 110465.92460504393 1.1048510216309744 0.7930832699982944 0.8838118545258341 0.8658052348494125 0.8334628420175624 0.7105374778238074 0.7984721472747718 0.7965902809993691 0.6633707039118207 1.0 16.753241884915163 -2.70876213534213 1.5568319560084571 0.805639824574421 199.9999964899953 0.4685993559919356 0.08984208623437377 807.1493057294248 3.8413712202475314 0.024418894730638928 572415.970571423 0.0019554101477451324 2.70876213534213 199.19435666542088 KIS(ph)VVSATK ddPTM_PC-9_AZD4547_30min_R2 1 KISVVSATK 9 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-3;Q9UKV3-2 S4R3H4 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 KIS(0.982)VVS(0.017)AT(0.001)K 54.199 0.044052 18462000.0 110900.0 95763.0 93862.0 138700.0 145980.0 106730.0 87936.0 146120.0 126730.0 100000.0 True False 146163.89313670134 126716.51700246832 92617.32855165869 106724.85789363855 125713.19679821919 100056.15622780383 95762.13364539557 123540.51150356253 133428.68907557716 96499.03043763124 1.514666960629923 1.3131377219833011 0.9597747058351912 1.1059681885883446 1.3027405169575201 1.0368617775125897 0.9923636870868673 1.280225417222286 1.382694608126805 1.0 16.55822682669858 -4.9702998091907995 4.21851289740751 1.1383952006606048 1.4930347017899601 0.42959691997174243 0.1386901384306269 0.20215218397752246 8.157545097338398 0.03654613476957391 0.15936765322494156 1.0707798519656589e-05 4.9702998091907995 0.3546395011293553 KIS(ph)VVSATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KISVVSATK 9 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-3;Q9UKV3-2 S4R3H4 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 KIS(0.998)VVS(0.002)ATK 60.157 0.032639 17564000.0 82434.0 79632.0 61364.0 61739.0 67985.0 71347.0 52450.0 81292.0 63485.0 51036.0 True False 96388.44805428517 87537.33869044593 62827.150484265905 58279.96399053861 54663.827284406005 67605.43772078474 47481.55629488404 79158.17113599379 64413.34802317978 60288.42279924631 1.5987886824514863 1.4519759288103364 1.0421097047682484 0.9666858292943631 0.9067052138091325 1.1213668326654236 0.7875733696499624 1.3129912421093122 1.0684198562909666 1.0 15.879593367185718 -5.18722414223962 3.1655976962960395 1.022522583286532 1.5749803257389687 0.7061124282475122 0.13044667656642414 0.1363473591182672 2.622967043065763 0.03458113667529484 0.11319225699678108 6.497942407036023e-06 5.18722414223962 0.5524577424524368 KIS(ph)VVSATK ddPTM_PC-9_Lapatinib_30min_R1 1 KISVVSATK 9 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-3;Q9UKV3-2 S4R3H4 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 KIS(0.998)VVS(0.002)ATK 56.413999999999994 0.039811 13806000.0 149840.0 118660.0 131100.0 107650.0 136400.0 97285.0 115670.0 115070.0 113980.0 140690.0 True False 147703.254122709 118385.25006044851 120321.46406063475 115566.9401098725 128377.22017271779 93124.34733241142 121658.8266223433 120416.57228368819 101142.3721373899 165008.07904235905 0.8951274081846154 0.7174512347971638 0.7291852905562712 0.7003714047250101 0.778005664436359 0.5643623504550075 0.7372901213589208 0.7297616758072566 0.6129540609428327 1.0 17.332177137144292 -10.560273315539591 4.214229678916263 1.0000239726911602 0.7161751581935167 0.5027839758593681 0.08402364465589046 31213461184.98994 62282362508.87725 10984453.585616741 0.020459632143308603 2.75249592359328e-11 10.560273315539591 -0.28384881449764343 KISENS(ph)YSLDDLEIGPGQLSSSTFDSEKNESR ddPTM_PC-9_AZD4547_30min_R2 1 KISENSYSLDDLEIGPGQLSSSTFDSEKNESR 32 2 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VRN8 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 KIS(0.117)ENS(0.41)Y(0.356)S(0.117)LDDLEIGPGQLSSSTFDSEKNESR 59.555 0.00025636 20075000.0 59359.0 49051.0 64231.0 73361.0 74672.0 86664.0 74251.0 62924.0 62747.0 67537.0 True False 78233.92725609962 64905.77650541515 63379.254972210154 56448.7548661515 64305.081732543025 81244.88637989685 80859.19515675324 53200.5416496727 66063.67831946065 65172.55018666299 1.2004122446033962 0.9959066557855453 0.9724838876288161 0.8661431032616437 0.986689665332484 1.2466120498154594 1.2406940487239118 0.8163028989551453 1.0136733660144548 1.0 15.991976827928175 -8.061756557575801 0.005386968563970453 0.00010176213040380806 2.047183432837126 0.013919943194036888 0.14051433453165563 35176.74858772339 188.8119445789906 35920.1156784094 35812.82645781971 8.674479847781801e-09 8.061756557575801 2.047081670706722 KISENSY(ph)SLDDLEIGPGQLSSSTFDSEKNESR ddPTM_PC-9_AZD4547_30min_R2 1 KISENSYSLDDLEIGPGQLSSSTFDSEKNESR 32 2 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VRN8 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 KIS(0.117)ENS(0.074)Y(0.591)S(0.218)LDDLEIGPGQLSSSTFDSEKNESR 49.958999999999996 0.017853 2108500.0 4541.1 5865.0 7280.8 8753.3 6671.2 8485.3 6167.9 6387.6 6642.0 6803.2 True False 5985.0753392522365 7760.746553673932 7184.25183480979 6735.361922136881 5745.0190332941565 7954.712849618511 6716.831151194442 5400.543192445639 6993.08256008825 6565.022038732916 0.9116611191768957 1.1821356437017836 1.0943225768966935 1.0259465821133544 0.8750951633367213 1.2116810579898392 1.0231239303639605 0.8226237719512625 1.0652032116312518 1.0 12.680584138905507 -7.537211993488117 24.97808396517087 0.9509228470803075 1.0547846526665408 0.1036193729789463 0.11310681608134565 464.2147841655879 808962.243605544 0.05186202823033193 0.02996011876841799 2.9026054509618533e-08 7.537211993488117 0.10386180558623326 KISENSYS(ph)LDDLEIGPGQLSSSTFDSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KISENSYSLDDLEIGPGQLSSSTFDSEK 28 1 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VRN8 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 KIS(0.234)ENS(0.339)Y(0.006)S(0.421)LDDLEIGPGQLSSSTFDSEK 112.98 1.4702999999999998e-11 9189900.0 22258.0 29453.0 23137.0 37108.0 49592.0 54844.0 70907.0 75635.0 69234.0 60572.0 True False 26025.839784461237 32376.899191904133 23688.673827561142 35028.9590657592 39874.80359915073 51967.884092655884 64190.1756377759 73649.66139190683 70246.41627214036 71553.22411231183 0.3637270033228746 0.45248693673236157 0.33106368191569924 0.48955109291479054 0.5572747293198442 0.7262829136963238 0.8970969014201415 1.0292989911440522 0.9817365624486707 1.0 16.126729154272855 -6.917952187416373 1.0637247986587064 1.0204617141912389 0.3887350999261989 0.9773541685534143 0.0395156858871643 0.06485661549794702 0.1535435301979212 0.022813993170972744 0.01770347115488121 1.2079468137223763e-07 6.917952187416373 -0.63172661426504 down KISPPS(ph)YAR ddPTM_PC-9_AZD4547_30min_R2 1 KISPPSYAR 9 1 F5H0Q6;A0A0A0MQS2;Q8N2M8-3;Q8N2M8;Q8N2M8-4 F5H0Q6 CLASRP CLK4-associating serine/arginine rich protein 1 KIS(0.024)PPS(0.907)Y(0.068)AR 56.086999999999996 0.040437 205780000.0 53754.0 45910.0 65429.0 81333.0 77490.0 55523.0 56030.0 61862.0 59026.0 63115.0 True False 70846.65384734201 60749.50968101793 64561.36870945083 62582.93343232378 66731.85107476376 52051.13803275881 61016.561455507544 52302.64934734048 62145.99385603268 60905.36306071083 1.1632252118211928 0.9974410565529748 1.0600276472384815 1.0275438859126533 1.0956646134470138 0.8546232288423259 1.0018257570303928 0.8587527718241312 1.0203698119997278 1.0 15.894281650709411 -6.744849241851956 24.999998019922494 0.9417058111382952 1.062040004945883 0.4520686221973865 0.06663435764820501 215.27430132534496 324400.4521684971 0.0204055998296954 0.02035102662620565 1.7994954718174385e-07 6.744849241851956 0.1203341938075877 KIT(ph)TYIS(ph)FPLELDMT(ph)PFMASSK ddPTM_PC-9_Lapatinib_30min_R1 1 KITTYISFPLELDMTPFMASSK 22 1 A6NNY8 A6NNY8 USP27X Ubiquitin carboxyl-terminal hydrolase 27 3 KIT(0.473)T(0.473)Y(0.068)IS(0.984)FPLELDMT(0.369)PFMAS(0.317)S(0.317)K 46.702 0.03977 0.0 14540.0 12340.0 14893.0 13171.0 15924.0 14707.0 13196.0 12492.0 15201.0 11196.0 True False 14332.656933690556 12311.427488167348 13668.555028642502 14139.639277167998 14987.381627788549 14078.015893691474 13879.224311476117 13072.423924288078 13488.903306373617 13131.21368226775 1.091495217463807 0.9375696554837554 1.0409209201355372 1.0767960692210816 1.1413553987037275 1.0721031760150455 1.0569643177932952 0.9955228999084021 1.027239646902471 1.0 13.680712646310909 -7.750210415747177 23.16495387798612 1.0085359611305262 1.0584753882401219 0.19108498222807413 0.0489912641901932 165.43163213771126 341283.95666426077 0.02552276659647445 0.0145303071154885 1.7774180420586013e-08 7.750210415747177 0.04993942710959565 KIY(ph)S(ph)SY(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 KIYSSYPK 8 1 Q9NR99 Q9NR99 MXRA5 Matrix-remodeling-associated protein 5 3 KIY(0.678)S(0.678)S(0.678)Y(0.965)PK 70.977 0.009592299999999998 1787300.0 14204.0 8049.4 4575.8 9317.9 7450.8 7711.0 7288.5 7108.4 8305.8 6633.7 True False 14001.448355305409 8030.762108853661 4199.595387098798 10003.169449603192 7012.558592836408 7381.218505218939 7665.862867095608 7438.682214490027 7370.313340048553 7780.326206150368 1.799596570158874 1.0321883550981863 0.539771119593804 1.2857005200753229 0.9013193543598419 0.9487029604727969 0.9852881054056221 0.9560887316793645 0.947301327060336 1.0 12.925614929093289 -4.76990088800998 4.9392762383325115 0.9459484023171697 1.8499191283164054 0.6924048827913893 0.16962796809926492 0.08947250918802015 5.602896400120193 0.04050457991645478 0.2781817678044196 1.6986312593102336e-05 4.76990088800998 0.9039707259992357 KKAEPSEVDMNS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 KKAEPSEVDMNSPK 14 2 Q9NR30 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 KKAEPSEVDMNS(1)PK;KKAEPS(0.001)EVDMNS(0.999)PK 69.188 0.0096809 202709000.0 668060.0 493090.0 466610.0 513340.0 493050.0 493810.0 585140.0 468040.0 502630.0 586990.0 True False 880489.1834887695 652471.6995995014 460422.44652244257 394997.39402393944 424598.5181625031 462931.982637045 637216.3264336197 395715.1724892383 529197.9956605178 566439.6587658509 1.554427148351802 1.1518820928271436 0.812835823546683 0.6973335780982445 0.7495917907436268 0.8172661915051521 1.1249500570316278 0.698600753611454 0.9342530796899451 1.0 19.11156275239626 -4.9086717622564136 2.3913349962967243 0.8430004207258484 1.623134321133278 0.7385994674302727 0.1296370504311345 0.20839893049364194 1.822128151392673 0.03493177631917041 0.3055937305242671 1.2340371603897276e-05 4.9086717622564136 0.7801339004074297 KKAEPSEVDMNS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KKAEPSEVDMNSPK 14 2 Q9NR30 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 KKAEPSEVDMNS(1)PK;KKAEPSEVDMNS(1)PK 71.607 0.0078976 40949000.0 476320.0 397590.0 312607.0 468460.0 397520.0 419430.0 511090.0 562480.0 428660.0 362732.0 True False 556951.5682511722 437060.1076192295 320060.7364486489 442213.70496781124 319628.8096211975 397434.35243568406 462675.8552288332 547715.4959968235 434928.34155495284 428492.4402150673 1.2997932191560466 1.019994909128063 0.746946051809001 1.0320221863094177 0.7459380367615602 0.9275177695928668 1.0797760049082983 1.2782384112119136 1.0150198713812904 1.0 18.708910225891408 -7.354732846413499 4.917399521929156 1.1211318317355161 0.9485584439282153 0.12474044840860721 0.16393159516544747 0.401901991528509 15.982124208319176 0.07208268260435838 0.04781295980160753 4.4184216026802667e-08 7.354732846413499 -0.1725733878073008 KKAEPSEVDMNS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 KKAEPSEVDMNSPK 14 2 Q9NR30 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 KKAEPSEVDMNS(1)PK;KKAEPSEVDMNS(1)PK 76.58800000000001 0.01192 163510000.0 420250.0 289820.0 221212.0 280793.0 252923.0 224588.0 226061.0 216762.0 211582.0 221224.0 True False 414257.1579355887 289148.939596488 203024.8032630138 301443.45391798904 238046.56640575003 214982.89478019887 237765.33245503186 226833.55384858625 187751.40710276586 259462.2736375496 1.5965988123355326 1.1144161173905713 0.7824829421892181 1.1618007107233022 0.9174611902857377 0.8285709200271433 0.9163772795237783 0.8742448397929968 0.7236173662959621 1.0 17.98516525736381 -4.8129853189306395 2.719354983085557 0.903969628596824 1.704335309339843 0.7705346620706683 0.11508544771209488 0.1905121389105029 2.0087602478523405 0.02977784689352629 0.3383836635785483 1.5382066375942465e-05 4.8129853189306395 0.8003656807430191 KKEEPSQNDIS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 KKEEPSQNDISPK 13 2 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 KKEEPS(0.002)QNDIS(0.998)PK;KKEEPS(0.001)QNDIS(0.999)PK;KKEEPS(0.003)QNDIS(0.997)PK;KKEEPS(0.014)QNDIS(0.986)PK 79.837 0.026208 263297400.0 283321.0 265027.0 196975.0 251702.0 234321.0 209379.0 248752.0 195563.0 211985.0 230421.0 True False 373411.1845571073 350691.79486454214 194362.9827988214 193675.99265713483 201789.5738248769 196286.49803074438 270890.44610352354 165343.23194067346 223190.09432404523 222354.03092469356 1.6793542397419972 1.5771775910971173 0.8741149507860637 0.8710253277249048 0.9075147996449796 0.8827656382682008 1.2182843952816318 0.7436034833866879 1.0037600550611778 1.0 17.76249903312827 -5.2318217039793415 5.987475587687721 0.9326135376709843 1.6393605516236118 0.8435238812853317 0.1190293379712113 0.06287237605559738 7.403322974416241 0.02977849830755215 0.07772278531446444 5.863788481092389e-06 5.2318217039793415 0.7067470139526275 KKEEPSQNDIS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KKEEPSQNDISPK 13 2 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 KKEEPSQNDIS(1)PK;KKEEPS(0.001)QNDIS(0.999)PK;KKEEPSQNDIS(1)PK 69.729 0.0095405 312119900.0 892521.0 847634.0 573834.0 935911.0 817049.0 686125.0 929723.0 922953.0 667760.0 729617.0 True False 1043607.1772067192 931781.5017020488 587516.3788375638 883474.9409343993 656954.1136853234 650143.3971459691 841652.906828379 898726.4616995383 677524.7267221953 861890.7864550059 1.2108345901910853 1.0810899899910829 0.6816598901747681 1.02504279523415 0.7622243142746706 0.7543222498293978 0.9765192064416118 1.0427382167479005 0.7860911583808475 1.0 19.717145545813857 -5.040163577869876 7.260621820330208 0.8798657127283371 1.1806047250591265 0.4481731989779725 0.12248140487297254 0.17273928778507783 27.29333277294126 0.030719906807128168 0.08635802568251914 9.116673933652838e-06 5.040163577869876 0.30073901233078937 KKEEPSQNDIS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 5 KKEEPSQNDISPK 13 2 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 KKEEPS(0.001)QNDIS(0.999)PK;KKEEPS(0.001)QNDIS(0.999)PK;KKEEPSQNDIS(1)PK;KKEEPS(0.002)QNDIS(0.998)PK;KKEEPS(0.001)QNDIS(0.999)PK 77.506 0.019536 1584520000.0 724632.0 571397.0 410380.0 454467.0 488519.0 439917.0 515408.0 436132.0 413631.0 395133.0 True False 714298.6147987657 570073.9653530275 376640.14051261055 487890.01923746837 459785.27288530755 421102.7754066139 542093.3043292882 456396.28489814297 367043.52105247235 463431.2125683729 1.541326081253927 1.230115602688114 0.8127207022272858 1.0527776420874693 0.9921327273947319 0.9086629557660317 1.169738441493752 0.9848199096663305 0.7920129484121015 1.0 18.82199568890531 -4.941794241070489 3.249635172280119 0.9735414655357132 1.54306894468652 0.744063191011277 0.1062508982771067 0.13041528761881852 2.564136408381433 0.027187361444711802 0.15392061876319127 1.143419933054242e-05 4.941794241070489 0.5695274791508068 KKEPAITSQNS(ph)PEAR ddPTM_PC-9_AZD4547_30min_R2 3 KKEPAITSQNSPEAR 15 2 A0A1W2PRL9;A0A1W2PPZ5;P23193-2;P23193;E5RIS7 A0A1W2PRL9 TCEA1 Transcription elongation factor A protein 1 1 KKEPAITS(0.004)QNS(0.996)PEAR;KKEPAIT(0.001)S(0.005)QNS(0.994)PEAR;KKEPAIT(0.03)S(0.433)QNS(0.536)PEAR 118.15 0.00033003 541841000.0 191547.0 170990.0 226449.0 261621.0 250995.0 216726.0 198764.0 248737.0 210486.0 232049.0 True False 252454.9615748936 226259.17360830423 223446.1383008518 201308.32045415693 216148.6767390672 203174.0889593085 216453.61094311107 210300.41205763546 221611.86024431454 223925.03514021842 1.127408382081129 1.0104237494776955 0.9978613519517068 0.8989987221754849 0.9652724922147191 0.907330834321781 0.9666342613614916 0.939155427288193 0.9896698692289793 1.0 17.772656307020085 -4.631198868192303 1.346651407947145 0.9504286935374686 1.2505497064093736 0.7164910954994648 0.03255060899217691 0.895527891317456 1.127275765865536 0.009041932675269678 0.4051613641313364 2.3377665046815358e-05 4.631198868192303 0.30012101287190496 KKEPAITSQNS(ph)PEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KKEPAITSQNSPEAR 15 2 A0A1W2PRL9;A0A1W2PPZ5;P23193-2;P23193;E5RIS7 A0A1W2PRL9 TCEA1 Transcription elongation factor A protein 1 1 KKEPAITSQNS(1)PEAR;KKEPAITS(0.001)QNS(0.999)PEAR;KKEPAITS(0.006)QNS(0.993)PEAR 94.325 0.0066476 444194000.0 343387.0 348877.0 365430.0 412433.0 404639.0 364186.0 413800.0 364652.0 338976.0 306533.0 True False 401515.6368976005 383511.2029122316 374143.23710099235 389325.71613582614 325352.89267536614 345087.44504718774 374601.868347437 355080.2713807311 343932.88272041245 362105.00638610765 1.1088375742296968 1.059115991628403 1.0332451374672476 1.0751735249986945 0.8985042651645826 0.9530037943723586 1.0345117072145755 0.9806002820135379 0.9498153205694193 1.0 18.466048597780812 -6.23355651250542 24.89955878206451 0.9708710898861529 1.0658198600201405 0.6289601089367387 0.03746584379089876 505.1821876693259 451130.4603924783 0.011596732337268722 0.014968128356580944 5.840412038724474e-07 6.23355651250542 0.09494877013398761 KKEPAITSQNS(ph)PEAR ddPTM_PC-9_Lapatinib_30min_R1 6 KKEPAITSQNSPEAR 15 2 A0A1W2PRL9;A0A1W2PPZ5;P23193-2;P23193;E5RIS7 A0A1W2PRL9 TCEA1 Transcription elongation factor A protein 1 1 KKEPAITS(0.001)QNS(0.998)PEAR;KKEPAIT(0.013)S(0.383)QNS(0.604)PEAR;KKEPAITSQNS(1)PEAR;KKEPAITSQNS(1)PEAR;KKEPAITS(0.01)QNS(0.99)PEAR;KKEPAITS(0.001)QNS(0.999)PEAR 196.45 1.3695e-08 584933100.0 394837.0 326463.0 411366.0 332841.0 353365.0 347866.0 313751.0 310585.0 334156.0 312458.0 True False 389206.55197576125 325707.09498132655 377545.07539868006 357319.23746502685 332580.7654423197 332988.58209525223 329995.4915845665 325015.9129462866 296519.8324613238 366465.94897588604 1.0620537953483138 0.88877860519248 1.0302323488819505 0.9750407601677037 0.9075352467855177 0.9086480832006668 0.9004806381241184 0.8868925308192088 0.8091333813959213 1.0 18.48331962770491 -6.27805965854209 3.4055034837412417 0.895174490974167 0.9862353050630303 0.33501224069318924 0.05989014444623015 0.2823282925548585 6.935456160397077 0.018220720106619417 0.022269838181665152 5.271574414269346e-07 6.27805965854209 0.09106081408886324 KKEQSEVSVS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KKEQSEVSVSPR 12 2 Q7L4I2;E9PI52 Q7L4I2 RSRC2 Arginine/serine-rich coiled-coil protein 2 1 KKEQS(0.007)EVS(0.134)VS(0.859)PR 48.214 0.038386 16993000.0 75594.0 63629.0 66703.0 81037.0 97428.0 82275.0 87600.0 83406.0 86850.0 71353.0 True False 88390.57115044325 69945.66661058861 68293.45249253607 76496.75961549897 78337.68279275014 77960.35416314017 79301.89383092176 81216.68087596179 88120.01694594251 84288.73406996274 1.048664120131118 0.8298341098886495 0.810232271798625 0.9075561575287613 0.9293968364470511 0.9249202164838568 0.9408362185757623 0.9635532170710852 1.0454542699953195 1.0 16.363052194731686 -7.642077733816799 0.9956901843259046 1.0211384335416986 0.8945979501080358 0.3309337384980704 0.06199964409702637 0.6301900076406218 1.1384670384531879 0.05380389440610736 0.023417331796688614 2.2799339529994815e-08 7.642077733816799 -0.12654048343366286 KKGDDS(ph)DEEDLCISNK ddPTM_PC-9_AZD4547_30min_R2 1 KKGDDSDEEDLCISNK 16 2 H3BRG5;Q9Y3M8-5;Q9Y3M8-3;Q9Y3M8-4;Q9Y3M8-2;Q9Y3M8 H3BRG5 STARD13 StAR-related lipid transfer protein 13 1 KKGDDS(1)DEEDLCISNK 58.071000000000005 0.017583 7101800.0 77804.0 80358.0 81052.0 81860.0 89060.0 84485.0 78719.0 71820.0 82609.0 92213.0 True False 102544.0535762656 106332.15201366226 79977.197521564 62988.44172439249 76695.55628750108 79202.13959435966 85724.83850109023 60721.86925941596 86975.54309038393 88984.6509374528 1.1523791181508787 1.19494936366501 0.8987752008802044 0.7078573783322136 0.8618964673065953 0.8900651827024725 0.9633665761227306 0.6823858791343385 0.9774218606703187 1.0 16.441268884997783 -5.3023794157252695 5.169011819510202 0.857098065289359 1.1752691758737324 0.5854864816327696 0.10091796434874237 0.11266397865333498 7.667610569457421 0.025556557756958875 0.05733926967715408 4.984488338457727e-06 5.3023794157252695 0.3181711105843734 KKGDDS(ph)DEEDLCISNK ddPTM_PC-9_Lapatinib_30min_R1 1 KKGDDSDEEDLCISNK 16 2 H3BRG5;Q9Y3M8-5;Q9Y3M8-3;Q9Y3M8-4;Q9Y3M8-2;Q9Y3M8 H3BRG5 STARD13 StAR-related lipid transfer protein 13 1 KKGDDS(0.999)DEEDLCIS(0.001)NK 46.361999999999995 0.038232 8654500.0 79546.0 82301.0 68381.0 72116.0 69413.0 79513.0 72370.0 73829.0 73025.0 71026.0 True False 78411.6594530502 82110.43709105832 62758.97813829333 77419.65121192372 65330.26381120869 76112.41434385601 76116.96449087051 77259.36486601553 64800.15551265925 83302.749463804 0.9412853712244033 0.9856869985634299 0.7533842345211286 0.9293769018460003 0.7842509908943095 0.9136843001433913 0.9137389219541212 0.9274527595224887 0.7778873558166969 1.0 16.346076493055442 KKLGAGEGGEASVS(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 2 KKLGAGEGGEASVSPEK 17 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 KKLGAGEGGEAS(0.015)VS(0.985)PEK;KKLGAGEGGEAS(0.016)VS(0.984)PEK 75.608 0.0028323 43792000.0 341710.0 252260.0 288290.0 337920.0 355170.0 338250.0 295790.0 280100.0 268700.0 338890.0 True False 450366.67199046 333798.1117868349 284467.08623466024 260017.76481195624 305860.77618046023 317099.1740284327 322114.73697884294 236816.98105767847 282902.9334380779 327025.56425008824 1.377160446227526 1.0207095355137663 0.8698619231404123 0.7950992009086827 0.9352809370785382 0.9696464395851804 0.9849833535720472 0.7241543382112353 0.8650789551783538 1.0 18.319043892959073 -4.777434837582306 2.4791480512919413 0.8878368558630927 1.4899126863777596 0.7585278939237395 0.08226338735181661 0.265880482964556 2.038046977357577 0.02244569917573005 0.34729598302510734 1.669418271296156e-05 4.777434837582306 0.602075830514667 KKLGAGEGGEASVS(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KKLGAGEGGEASVSPEK 17 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 KKLGAGEGGEAS(0.049)VS(0.951)PEK;KKLGAGEGGEAS(0.172)VS(0.828)PEK 60.968 0.010787 58660000.0 429880.0 246530.0 317010.0 473560.0 441440.0 511010.0 545090.0 480820.0 487940.0 453360.0 True False 502650.19348298246 271003.86913998943 324568.7206671195 447027.9685022343 354943.0009035553 484211.7360183083 493455.1290901502 468198.9844709 495075.1994082117 535550.5792042142 0.9385671736736443 0.5060285240334905 0.6060468110209178 0.8347072823009221 0.6627627990449988 0.904138198744568 0.9213978067643686 0.8742385923036563 0.9244228624378567 1.0 19.030663308835685 -6.770399999020196 22.41828375581674 0.916764532874022 0.6995066835056672 0.4656399934061942 0.11485814078861341 49.35895692313385 123487.26914541854 0.03962468571603734 0.03555215280193963 1.6966802361743147e-07 6.770399999020196 -0.2172578493683548 KKLGAGEGGEASVS(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 1 KKLGAGEGGEASVSPEK 17 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 KKLGAGEGGEAS(0.019)VS(0.981)PEK 48.919 0.029135 29845000.0 283970.0 176510.0 144600.0 168050.0 147170.0 140020.0 121810.0 109000.0 144550.0 115170.0 True False 279920.53572627925 176101.3019397418 132711.54617214197 180408.9575983663 138513.74994735248 134031.67100256207 128116.72577909249 114064.53792406338 128269.25682101873 135076.98104562124 2.0723037601183742 1.303710673547441 0.9824882459234089 1.3356010491338604 1.0254430390369067 0.9922613754396382 0.9484719364272882 0.8444409775899487 0.9496011520845047 1.0 17.04342231519346 -1.9736266321801528 0.8879850513511829 0.9806871500896411 199.99999999998974 0.8808301848105098 0.11826174649927526 111.84404331386092 0.6473491207288586 0.042377862284532705 44558.6066967414 0.01062608701198762 1.9736266321801528 199.0193128499001 up KKPAPLPPS(ph)SSPGPPSQDSR ddPTM_PC-9_AZD4547_30min_R2 1 KKPAPLPPSSSPGPPSQDSR 20 2 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 KKPAPLPPS(0.501)S(0.13)S(0.349)PGPPS(0.019)QDS(0.001)R 69.876 0.012495000000000001 15778000.0 16805.0 15710.0 21386.0 34554.0 29832.0 22103.0 17438.0 23445.0 19174.0 22247.0 True False 22148.64043428548 20787.950274205883 21102.40766663584 26588.10915397826 25690.34173780298 20720.895915891957 18989.948218117792 19822.113962503605 20187.498495503183 21468.13930145979 1.0316981888029495 0.9683163492791546 0.9829639807303152 1.2384915516255441 1.196672956936519 0.9651929133179687 0.8845642350022629 0.923327060820578 0.9403469118597751 1.0 14.389909534095647 -6.9767990141958744 22.09855090988131 0.9298427593692309 1.080303600422954 0.4165806102981764 0.08370714533039458 67.51277020800521 64303.558344285564 0.03319073847557638 0.029267646444057056 1.0548749657791725e-07 6.9767990141958744 0.15046084105372315 KKPAPLPPS(ph)SSPGPPSQDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KKPAPLPPSSSPGPPSQDSR 20 2 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 KKPAPLPPS(0.332)S(0.332)S(0.332)PGPPS(0.003)QDS(0.001)R 44.089 0.029418 30680000.0 134830.0 157070.0 143420.0 178400.0 196810.0 178090.0 177490.0 165410.0 130850.0 126060.0 True False 157654.05598611306 172662.8715605334 146839.67672337865 168404.826380604 158246.49331240606 168750.64689047265 160676.86228367887 161068.1627663823 132763.43370612062 148913.68010958936 1.0586942440082834 1.1594829396027713 0.9860724455625273 1.1308888898365188 1.0626726382421579 1.1332111782227445 1.0789932944067508 1.081620994443547 0.8915462542354513 1.0 17.184116769120365 -8.244057618673517 22.63014924129924 0.9457731821115782 1.0875410741048734 0.540835980974371 0.05184217077310263 140.3152321252134 182685.0291872973 0.032403118403364205 0.012156761886335937 5.700886325219082e-09 8.244057618673517 0.1417678919932952 KKPAPLPPS(ph)SSPGPPSQDSR ddPTM_PC-9_Lapatinib_30min_R1 1 KKPAPLPPSSSPGPPSQDSR 20 2 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 KKPAPLPPS(0.55)S(0.328)S(0.116)PGPPS(0.005)QDSR 110.1 0.00021088 7641200.0 31608.0 20773.0 25094.0 23277.0 23577.0 18078.0 15183.0 19643.0 21131.0 14887.0 True False 31157.2641238027 20724.90139478933 23030.868185641222 24988.868229795728 22190.247214165454 17304.846081876294 15969.10144901045 20555.68549029705 18751.00426070529 17460.198114319388 1.7844736880877732 1.1869797386658807 1.3190496485119054 1.4311904175532784 1.2709046637888306 0.9911025045978323 0.9146002436200271 1.1772882160735052 1.073928493705194 1.0 14.091782308329206 -6.5928143999118225 3.5788448151322045 1.0357567161002357 1.4020356894074315 0.5938322234315536 0.15528660314248155 0.18020277918033323 4.647411572037999 0.05299575173545181 0.053787769280047006 2.5537924582220076e-07 6.5928143999118225 0.36627897330719583 KKPAPLPPSS(ph)SPGPPSQDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KKPAPLPPSSSPGPPSQDSR 20 2 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 KKPAPLPPS(0.054)S(0.47)S(0.47)PGPPS(0.005)QDS(0.001)R 56.335 0.0067062 33731000.0 111450.0 110450.0 133120.0 138690.0 154180.0 151400.0 149350.0 136300.0 112430.0 92924.0 True False 130316.28376216229 121414.7460613796 136294.08566041169 130919.64893904653 123969.53579039074 143460.31747553256 135202.48679963648 132722.26942178738 114074.07605333702 109770.38561402092 1.187171594899791 1.106079252452506 1.241628922937872 1.1926682065178444 1.129353195736211 1.3069127586011544 1.2316845389888758 1.2090899442448058 1.039206297903051 1.0 16.744129364021383 -8.324828778512813 4.124200313986036 1.0051850392179094 1.2010646781547387 0.6489832287601782 0.05346880916683113 0.14213866919722998 4.6032185693891945 0.052100341611990016 0.014068903681048784 4.733378365893342e-09 8.324828778512813 0.19587963893682936 KKPCSETSQIEDTPS(ph)SKPTLLANGGHGVEGSDTTGSPTEFLEEK ddPTM_PC-9_AZD4547_30min_R2 1 KKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEK 44 3 P27816;P27816-6;P27816-2;P27816-5;H7C456 P27816 MAP4 Microtubule-associated protein 4 1 KKPCS(0.024)ET(0.024)S(0.116)QIEDT(0.107)PS(0.255)S(0.097)KPT(0.255)LLANGGHGVEGS(0.087)DT(0.005)T(0.006)GS(0.012)PT(0.013)EFLEEK 43.055 0.012453 9506300.0 18304.0 14298.0 21373.0 28291.0 28972.0 22337.0 22199.0 29239.0 21061.0 25832.0 True False 24124.291253148553 18919.548887370816 21089.580055129874 21768.94704159284 24949.737893122427 20940.263858900522 24174.66799483868 24720.784395378243 22174.241463116326 24927.629542648854 0.9677731776250179 0.758979061968216 0.8460323120193826 0.8732858856213424 1.000886901437449 0.8400423242440153 0.9697940974884144 0.9917021734089589 0.8895447288791846 1.0 14.605458077875745 -6.07189385606097 6.373813671261248 0.943762588883917 0.84947170692723 0.28492149058977834 0.06731269068656738 0.28899994505463833 20.742662649511214 0.019201210893653703 0.02510107851036926 8.474345064456744e-07 6.07189385606097 -0.094290881956687 KKPGDASSLPDAGLS(ph)PGSQVDSK ddPTM_PC-9_AZD4547_30min_R2 2 KKPGDASSLPDAGLSPGSQVDSK 23 2 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 KKPGDAS(0.001)S(0.001)LPDAGLS(0.72)PGS(0.273)QVDS(0.005)K;KKPGDASSLPDAGLS(0.737)PGS(0.233)QVDS(0.03)K 94.031 3.0126999999999998e-05 49523000.0 106290.0 109278.0 118506.0 204519.0 203836.0 209095.0 157906.0 196773.0 166764.0 183745.0 True False 140088.0090306575 144599.97645223883 116934.53300955516 157370.30433705138 175536.88986547355 196020.25659564004 171959.32809554457 166366.2542437076 175578.80458454633 177312.1434776256 0.7900643818472294 0.8155108477975475 0.6594840641826132 0.8875325809645372 0.9899879750064832 1.1055094859894645 0.9698113435600282 0.9382676842136353 0.9902243644508308 1.0 17.435931819105548 -6.02522100511221 3.7852690752259965 0.9979584793769174 0.7606981333665785 0.7919784394119296 0.05584029794451833 0.10352035537734083 3.2118717434762867 0.017545876250187727 0.024813802672934225 9.435805818996716e-07 6.02522100511221 -0.23726034601033885 KKPGDASSLPDAGLS(ph)PGSQVDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KKPGDASSLPDAGLSPGSQVDSK 23 2 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 KKPGDASSLPDAGLS(0.747)PGS(0.252)QVDS(0.001)K;KKPGDAS(0.001)S(0.001)LPDAGLS(0.848)PGS(0.148)QVDS(0.002)K 112.01 1.4682e-06 24861200.0 128780.0 132121.0 117956.0 169665.0 215605.0 201260.0 247943.0 186994.0 217614.0 211375.0 True False 150579.91047906026 145237.09972273005 120768.51839062109 160159.2201113514 173358.74798344282 190705.57130201906 224456.04408813076 182085.60563652034 220796.1930647591 249695.61425642043 0.6030538859382004 0.5816565907864982 0.48366295399405784 0.6414178342230663 0.694280308045039 0.7637521863166463 0.8989186484374116 0.7292302917644793 0.8842613985122558 1.0 17.929810955910867 -7.002919600576617 0.41465819280435184 0.9742082597274484 0.5028113336899307 0.8219902228498687 0.0645755021257406 0.5484700384537792 0.20725748520498896 0.0715985253142773 0.09653227674855745 9.932999175517439e-08 7.002919600576617 -0.4713969260375177 KKPGDASSLPDAGLS(ph)PGSQVDSK ddPTM_PC-9_Lapatinib_30min_R1 1 KKPGDASSLPDAGLSPGSQVDSK 23 2 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 KKPGDASSLPDAGLS(0.974)PGS(0.023)QVDS(0.003)K 68.42 0.00042046 21247000.0 195290.0 143830.0 129850.0 116790.0 208140.0 187610.0 188340.0 188330.0 206440.0 161670.0 True False 192505.12878819995 143496.97047188922 119174.23423549521 125379.1262000187 195897.61441898462 179586.35764027032 198091.32364530262 197080.49933246686 183188.55329042644 189614.4440882659 1.0152450659222376 0.7567829084006442 0.6285082067905089 0.6612319372761205 1.0331365596167024 0.9471132777030029 1.0447058745856443 1.0393749288462724 0.9661107526447289 1.0 17.532709341736258 -6.270921292580557 24.971650405165654 1.006125923147027 0.755042532855079 0.5763865696802902 0.10048108393802738 487.5887967830767 1284115.9385286777 0.03266988866155892 0.03752894407917499 5.358937690254595e-07 6.270921292580557 -0.2510833902919479 KKS(ph)EPDDELLFDFLNSSQK ddPTM_PC-9_AZD4547_30min_R2 1 KKSEPDDELLFDFLNSSQK 19 2 Q8TBA6-2;Q8TBA6 Q8TBA6-2 GOLGA5 Golgin subfamily A member 5 1 KKS(1)EPDDELLFDFLNSSQK 68.845 0.0026079999999999996 2163700.0 14599.0 17981.0 15051.0 10370.0 10914.0 14032.0 20934.0 14597.0 19322.0 14067.0 True False 19241.178321935968 23793.00661238039 14851.413905851297 7979.35671490289 9398.779489353114 13154.576821779652 22797.08544546839 12341.36905569056 20343.32147335519 13574.518611661573 1.4174482994488136 1.7527698250706538 1.094065604145459 0.5878187612522774 0.6923839996269795 0.969063964484077 1.67940286485621 0.9091570322860922 1.4986403610569796 1.0 13.728613416703743 KKS(ph)IFET(ph)Y(ph)MSK ddPTM_PC-9_AZD4547_30min_R2 1 KKSIFETYMSK 11 2 C9JGP4;Q8IYB7-4;Q8IYB7-5;Q8IYB7-3;Q8IYB7-2;Q8IYB7 C9JGP4 DIS3L2 DIS3-like exonuclease 2 3 KKS(1)IFET(0.926)Y(0.837)MS(0.238)K 59.708999999999996 0.021703999999999998 5549800.0 18499.0 16494.0 30785.0 43009.0 36308.0 34969.0 23686.0 37557.0 21672.0 33280.0 True False 24381.297196896598 21825.362942250278 30376.77078543832 33093.9395324261 31267.2609216999 32782.38290199635 25794.008114137967 31753.428624002885 22817.537675735097 32114.877329643623 0.7591901082677172 0.6796028743383798 0.9458784622975674 1.0304862507408288 0.9736067368639353 1.0207849329611665 0.8031794065216254 0.9887451319856949 0.7104974258977903 1.0 14.97095416529022 -5.266475011404112 24.678389700718025 0.9370120605357909 0.7193964838322351 0.433850915000094 0.09808364914845986 282.8749202869251 1386308.9311965846 0.025143239248908152 0.05511489108803368 5.4140839874238765e-06 5.266475011404112 -0.2176155767035558 KKS(ph)IPLSIK ddPTM_PC-9_AZD4547_30min_R2 1 KKSIPLSIK 9 2 Q9C0C9;K7ES11 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 1 KKS(0.971)IPLS(0.029)IK 48.284 0.040481 6759600.0 52571.0 46453.0 51337.0 75378.0 66152.0 40456.0 44362.0 57224.0 47168.0 57781.0 True False 69287.48445527068 61468.02381207416 50656.23783700007 58000.76667849084 56967.936666638 37926.27992459505 48310.132059418625 48381.34567670318 49661.20418461951 55758.10477716761 1.242644181185355 1.102405184999127 0.9084999936680649 1.0402212720515849 1.0216978660645906 0.680193132032807 0.8664234957856951 0.8677006844126965 0.8906544507401422 1.0 15.766893904259202 -3.7734588924633496 0.5799377617120496 0.8708361649575881 2.252130631602988 0.5718258755806077 0.09594565940017921 7.940932306419854 0.837624111012597 0.04829672366351383 9.556582315660918 0.00016847718889534196 3.7734588924633496 1.3812944666453997 KKS(ph)IPLSIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KKSIPLSIK 9 2 Q9C0C9;K7ES11 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 1 KKS(1)IPLSIK 47.261 0.042172 7276200.0 57294.0 52920.0 34329.0 47823.0 45787.0 40905.0 31409.0 49812.0 31578.0 31007.0 True False 66992.74259191853 58173.54786390407 35147.53355345751 45143.63235425792 36815.36603472967 38759.86979086297 28433.712138532188 48504.48778017661 32039.768510293303 36628.32364872305 1.828987404239398 1.5882121284557376 0.9595725398337425 1.2324787993903108 1.0051064959401474 1.0581939310841004 0.7762766434855244 1.3242344434146003 0.8747265863861144 1.0 15.160672054960772 -5.1270021754059725 3.276447888888765 1.0376627982102056 1.7988145226430128 0.7660124783165532 0.15232727768282997 0.10970804017811421 2.134528764583753 0.03794056919534244 0.132784718435602 7.464450194147812e-06 5.1270021754059725 0.7611517244328072 KKS(ph)MEELTVIQCTSQELPAQTGLLSQTGDVPLPAGR ddPTM_PC-9_Lapatinib_30min_R1 1 KKSMEELTVIQCTSQELPAQTGLLSQTGDVPLPAGR 36 2 A0A096LNZ0;A0A096LP25;Q6ZSR9 A0A096LNZ0;A0A096LP25 AAK1 Uncharacterized protein FLJ45252 1 KKS(0.456)MEELT(0.456)VIQCT(0.042)S(0.042)QELPAQT(0.005)GLLSQTGDVPLPAGR 57.981 0.00011526 5527100.0 11950.0 10339.0 11645.0 8664.5 12543.0 12153.0 8632.0 9567.8 11877.0 10356.0 True False 11779.590808638392 10315.060680726265 10687.593050999925 9301.716233924688 11805.2454004868 11633.244520026683 9078.922723299616 10012.354916971148 10539.287189645389 12146.020801497392 0.9698312724103167 0.8492543236427356 0.8799254690624547 0.7658241646332393 0.9719434532033255 0.9577823642943627 0.7474812427606203 0.8243321068359112 0.8677152264012324 1.0 13.568196124638105 -7.231844189774066 24.992877555298453 0.8452430610460804 0.8932104654630354 0.036639302301296195 0.08308093923435998 2076.51175467276 1753598.629977239 0.031683597439026656 0.024538042450279334 5.8634848886308184e-08 7.231844189774066 0.04796740441695502 KKS(ph)PIINESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KKSPIINESR 10 2 Q13523 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 KKS(0.999)PIINES(0.001)R 45.891000000000005 0.044974 6910200.0 33762.0 34139.0 33906.0 37875.0 38746.0 41707.0 50777.0 46982.0 39663.0 35795.0 True False 39477.239770104236 37528.09430320901 34714.44762922107 35752.986542406776 31153.999440488264 39519.811499022646 45967.03496635514 45748.77228154378 40242.99633997604 42284.350146935896 0.9336134913489955 0.8875173479739159 0.8209762597412562 0.8455370939405956 0.7367737551181407 0.9346202876878414 1.0870933290123204 1.0819315449467521 0.9517231836396619 1.0 15.367836186084883 -7.010069638855192 6.764264479267113 1.0339993433624262 0.8446788133837523 0.6852578022635492 0.05918370834494875 0.08651735883733465 20.270869156099455 0.02272353912392474 0.01871415957986253 9.770805341263371e-08 7.010069638855192 -0.18932052997867388 KKS(ph)PIINESR ddPTM_PC-9_Lapatinib_30min_R1 1 KKSPIINESR 10 2 Q13523 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 KKS(0.999)PIINES(0.001)R 63.426 0.017649 203070000.0 221600.0 165100.0 168390.0 167920.0 159060.0 157460.0 144000.0 169170.0 157220.0 140900.0 True False 218439.9433635372 164717.72109371342 154545.62420419723 180269.39696469862 149704.40352399208 150725.80285718787 151455.61540258882 177030.25578544784 139512.2280000039 165254.37726255137 1.3218405889272522 0.9967525449084758 0.9351983697149493 1.0908600422625527 0.9059028027205964 0.9120835729374906 0.9164998707535628 1.0712591019854638 0.8442271261495901 1.0 17.334328960822354 -4.761659462013753 4.252384447452334 0.9616844296629561 1.3565871572842532 0.6905230142887888 0.07230759533367594 0.1236113936652502 4.532938733344795 0.01746367333605895 0.1525341945692461 1.7311732707437194e-05 4.761659462013753 0.3949027276212971 KKS(ph)PNELVDDLFK ddPTM_PC-9_AZD4547_30min_R2 1 KKSPNELVDDLFK 13 2 Q9UNZ2-4;Q9UNZ2;Q9UNZ2-5;F2Z2K0 Q9UNZ2-4 NSFL1C NSFL1 cofactor p47 1 KKS(1)PNELVDDLFK 110.31 0.00022089 116310000.0 88980.0 84113.0 96433.0 103950.0 106780.0 103240.0 89125.0 93015.0 87570.0 97460.0 True False 117273.78910102464 111300.88233063511 95154.2354117972 79985.93351149047 91955.44015696578 96784.38647951346 97056.9523419971 78641.66902206319 92198.77142230186 94047.95506451526 1.2469573529863234 1.1834481914496136 1.0117629388807343 0.8504803050382277 0.9777505538944036 1.029096128811318 1.0319942871210512 0.8361869109021708 0.9803378644336828 1.0 16.521108954341443 -5.2593411256686595 3.0364729788699294 0.9565011037487322 1.2328783789407252 0.719156926103723 0.06371079343401058 0.1347395742444782 2.5045036079014174 0.017748997886534643 0.05239316392506661 5.503752228695957e-06 5.2593411256686595 0.27637727519199295 KKS(ph)PNELVDDLFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 KKSPNELVDDLFK 13 2 Q9UNZ2-4;Q9UNZ2;Q9UNZ2-5;F2Z2K0 Q9UNZ2-4 NSFL1C NSFL1 cofactor p47 1 KKS(1)PNELVDDLFK;KKS(1)PNELVDDLFK;KKS(1)PNELVDDLFK;KKS(1)PNELVDDLFK;KKS(1)PNELVDDLFK 124.38 4.938e-05 101077500.0 535315.1 511684.0 477439.7 647988.0 655071.0 600548.0 668626.0 575589.0 540044.4 500142.5 True False 625933.3734748324 562480.6059182525 488823.67314814456 611683.3331654412 526714.5400165207 569054.2056756677 605288.9048469611 560480.3986369559 547941.5276863716 590814.3761241491 1.0594416770645805 0.95204285584286 0.8273726789705385 1.0353223582306785 0.8915059641437043 0.9631691926807332 1.0244992832059499 0.9486573470229522 0.9274343174940474 1.0 19.172345405669304 -6.994753107026109 24.958337374562994 0.9741499099787398 0.9483234880735057 0.021367215291682173 0.06619873274002536 632.2205535651618 3007316.654556933 0.023382470187903053 0.020552532852511296 1.0121546926629429e-07 6.994753107026109 -0.025826421905234098 KKS(ph)PNELVDDLFK ddPTM_PC-9_Lapatinib_30min_R1 3 KKSPNELVDDLFK 13 2 Q9UNZ2-4;Q9UNZ2;Q9UNZ2-5;F2Z2K0 Q9UNZ2-4 NSFL1C NSFL1 cofactor p47 1 KKS(1)PNELVDDLFK;KKS(1)PNELVDDLFK;KKS(1)PNELVDDLFK 100.19 0.00074098 76914100.0 450378.0 358627.0 347824.0 344732.0 402269.0 368949.0 318829.0 345788.0 356098.0 309718.0 True False 443955.5271307908 357796.62121547677 319227.2533594678 370084.7412722406 378608.32831128343 353169.9113321264 335336.40557772166 361854.5728411572 315990.4933618204 363252.3436267056 1.2221683766671563 0.9849809023755801 0.8788030110757387 1.0188089568186138 1.0422736011315548 0.9722439993258782 0.9231500125497564 0.9961520667104496 0.8698925111039241 1.0 18.470612580285895 -4.766014586155576 5.107812486002964 0.9642218991890668 1.2367808827437103 0.6710261709517888 0.05416909749486801 0.09696853736481656 6.9327092851129954 0.013586838304714764 0.09418672713897473 1.71389974373739e-05 4.766014586155576 0.2725589835546436 KKS(ph)PVPVETLK ddPTM_PC-9_Lapatinib_30min_R1 1 KKSPVPVETLK 11 2 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 KKS(1)PVPVETLK 52.693000000000005 0.031441000000000004 6157800.0 62367.0 60965.0 58883.0 60933.0 67956.0 62850.0 63552.0 66153.0 72762.0 52591.0 True False 61477.6351432929 60823.83928817847 54041.86703495307 65414.21608652931 63958.96168663651 60162.05201050587 66842.4115976757 69226.70988339985 64566.77734217212 61681.28427689737 0.9966983642446506 0.9860987818465372 0.8761469166619537 1.060519683618684 1.0369265561902743 0.9753696395235316 1.0836741222444264 1.1223292558668174 1.0467806904331192 1.0 15.912545183722985 -6.363334881678759 1.0119122475537887 1.0637877278305066 0.9626182778682691 0.29430861280377196 0.054393231860138475 0.636145829349898 1.385794031996937 0.026660566318864102 0.03692494973859749 4.331767297868691e-07 6.363334881678759 -0.10116944996223742 KKSMEELT(ph)VIQCTSQELPAQTGLLSQTGDVPLPAGR ddPTM_PC-9_AZD4547_30min_R2 1 KKSMEELTVIQCTSQELPAQTGLLSQTGDVPLPAGR 36 2 A0A096LNZ0;A0A096LP25;Q6ZSR9 A0A096LNZ0;A0A096LP25 AAK1 Uncharacterized protein FLJ45252 1 KKS(0.447)MEELT(0.528)VIQCT(0.02)S(0.004)QELPAQTGLLSQTGDVPLPAGR 62.666000000000004 4.7883e-05 7498400.0 17673.0 17413.0 19159.0 32510.0 30469.0 22341.0 22385.0 24717.0 23071.0 24727.0 True False 23292.646378763908 23041.41172022578 18904.939141731786 25015.321774493066 26238.90528322338 20944.013738268208 24377.22163450895 20897.55559015575 24290.485959620015 23861.315256313053 0.9761677480289486 0.9656387953773693 0.7922840354213104 1.048363072436868 1.09964203571223 0.8777392827382804 1.0216210369233274 0.875792275726579 1.0179860455593879 1.0 14.542385947371487 -5.812429400421553 24.999999790529248 0.9874259854314512 0.9167863898985339 0.17108252044123273 0.08029574686102431 204.0334812358069 100034.85380117722 0.022919630933432675 0.03399535996647252 1.5401768792306352e-06 5.812429400421553 -0.07063959553291732 KKT(ph)LCGTPNYIAPEVLSK ddPTM_PC-9_Lapatinib_30min_R1 1 KKTLCGTPNYIAPEVLSK 18 2 P53350 P53350 PLK1 Serine/threonine-protein kinase PLK1 1 KKT(0.885)LCGT(0.113)PNY(0.002)IAPEVLSK 73.809 0.0031538 10383000.0 180650.0 205650.0 220570.0 192930.0 182490.0 176360.0 161820.0 147760.0 172380.0 128700.0 True False 178073.89787284774 205173.83006009847 202435.58602482223 207118.71579561353 171756.29698914418 168817.49391523981 170198.24780865916 154625.4690244004 152964.7491581269 150945.62351802934 1.1797221656550918 1.3592565672206585 1.3411159681661309 1.3721412450946266 1.1378686773825486 1.1183993943029147 1.127546753870146 1.0243786167535458 1.0133765099844474 1.0 17.203669402733418 -6.57052192774249 1.7454825052423166 1.0504703296643307 1.3187121026222905 0.7753747093512167 0.06465845328937207 0.16999528535366024 1.0559507146977851 0.025947315320128478 0.027338426277410982 2.6883021059392756e-07 6.57052192774249 0.2682417729579598 KKT(ph)TPTPSTNSVLSTSTNR ddPTM_PC-9_AZD4547_30min_R2 1 KKTTPTPSTNSVLSTSTNR 19 2 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 KKT(0.452)T(0.452)PT(0.09)PS(0.004)T(0.001)NSVLSTSTNR 57.36600000000001 0.012559 10182000.0 18222.0 19645.0 31074.0 49070.0 44656.0 38778.0 33190.0 50609.0 33600.0 41555.0 True False 24016.216958854504 25994.862071086834 30661.938456609092 37757.6696239426 38456.28521866889 36353.20552985829 36143.84570245037 42788.541929125386 35376.02740424048 40100.17209835759 0.5989055832465655 0.648248142360255 0.7646335876415088 0.9415837301478581 0.95900549065833 0.906559838214441 0.9013389172943411 1.067041353941668 0.8821914109862237 1.0 15.291320807873392 -5.521120009426585 1.869198572872136 0.954043919136636 0.6073587133067374 0.871517029571555 0.0513107850767386 0.11542038919948043 0.7835135882087014 0.014978996735791946 0.04089996319868698 3.0121735494814745e-06 5.521120009426585 -0.3466852058298986 KKT(ph)TPTPSTNSVLSTSTNR ddPTM_PC-9_Lapatinib_30min_R1 1 KKTTPTPSTNSVLSTSTNR 19 2 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 KKT(0.49)T(0.49)PT(0.013)PS(0.005)T(0.002)NSVLSTSTNR 69.975 0.0034717 6803300.0 54076.0 28812.0 39448.0 36615.0 30615.0 30163.0 23674.0 25190.0 30592.0 22002.0 True False 53304.8663236761 28745.28758420401 36204.73771368357 39307.789244059386 28814.285891405856 28872.99880338724 24899.723882228365 26360.41936061614 27146.406811958524 25805.016384177838 2.0656784529832577 1.113941845889661 1.4030116150549026 1.523261549570675 1.1166156789992636 1.1188909308769326 0.9649179644580832 1.0215230623445308 1.0519817700485226 1.0 14.655363926170816 -1.5228787452803376 0.40025198589494204 1.014819278157876 14.467961162145789 0.6678703806385435 0.1868024762692476 47.62114852245613 0.6314273515162485 0.13697836459262608 505.2904971760376 0.029999999999999995 1.5228787452803376 13.453141883987913 KKTEFLDLDNSPLSPPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 KKTEFLDLDNSPLSPPSPR 19 2 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 KKTEFLDLDNSPLS(0.001)PPS(0.999)PR;KKTEFLDLDNSPLSPPS(1)PR 107.95 6.1633e-05 71837000.0 415720.0 348760.0 517490.0 790720.0 700470.0 595700.0 522830.0 609680.0 432940.0 593300.0 True False 547910.3124868296 461489.84962648223 510627.744478041 608431.72050222 603221.8314923196 558450.7848299706 569360.857144083 515467.9650526428 455824.3245354724 572528.7475864643 0.9570005258191567 0.8060553318447774 0.891881406183757 1.0627094675457036 1.0536096816714342 0.9754109067608564 0.9944668447554194 0.9003355154228233 0.7961597150484273 1.0 19.12698860949648 -5.548144115775392 24.821166085274875 0.9702496553000018 0.8733880014490422 0.18784192363224106 0.07982226603398464 313.8215529765054 308302.5908805324 0.023111527695841044 0.040032341220790135 2.830452585849973e-06 5.548144115775392 -0.09686165385095968 KKTEFLDLDNSPLSPPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KKTEFLDLDNSPLSPPSPR 19 2 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 KKTEFLDLDNSPLSPPS(1)PR;KKTEFLDLDNSPLSPPS(1)PR 104.97 0.00029130000000000003 44303000.0 156225.0 128715.0 156543.0 196535.0 208411.0 194755.0 187498.0 194155.0 199675.0 162665.0 True False 182670.80691560148 141492.9745521999 160275.57881263387 185523.78112506671 167574.36064088173 184541.70495341695 169736.8320720334 189058.63697422727 202594.8691270131 192154.87684456806 0.9506436157920772 0.7363486000235737 0.8340958160654908 0.9654908799173223 0.8720796650736622 0.9603800225309435 0.8833334592352378 0.9838867484334248 1.054331133582885 1.0 17.5519100665554 -7.069750296966926 0.5250799357821239 1.0249923014106814 0.8354713494853059 0.4339573963137421 0.06633936810505019 0.8765076476783034 0.5156869617318801 0.0618572157657219 0.06071403494114645 8.516275513533956e-08 7.069750296966926 -0.18952095192537555 KKTEFLDLDNSPLSPPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 KKTEFLDLDNSPLSPPSPR 19 2 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 KKTEFLDLDNSPLSPPS(1)PR;KKTEFLDLDNSPLSPPS(1)PR;KKTEFLDLDNSPLS(0.001)PPS(0.999)PR 93.38799999999999 0.00026267 35894200.0 433339.0 309443.0 361386.0 305457.0 312093.0 322260.0 249067.0 273502.0 361545.0 253059.0 True False 427159.5063953609 308726.5037456212 331674.23807030084 327921.3267546811 293736.303338446 308477.691024751 261962.47056580946 286209.9013881401 320823.99486236786 296799.9109700786 1.4392170974688208 1.0401839499768075 1.1175011373360486 1.1048565536387238 0.9896778687647874 1.0393456319326513 0.8826231440218282 0.9643193640209478 1.0809437031627385 1.0 18.17913113363594 -1.7849782236841898 0.9804896946117241 1.0048681116223377 199.99975762036834 0.7608047147720431 0.0690273750021933 404.6478541952182 1.0880521330988269 0.022881608644700346 180132.54169662064 0.016406720374193332 1.7849782236841898 198.994889508746 KLCQPQSTGSLLGDPAAS(ph)SPPGER ddPTM_PC-9_AZD4547_30min_R2 2 KLCQPQSTGSLLGDPAASSPPGER 24 1 U3KQ90;P55199 U3KQ90 ELL RNA polymerase II elongation factor ELL 1 KLCQPQSTGSLLGDPAAS(0.736)S(0.264)PPGER;KLCQPQSTGSLLGDPAAS(0.5)S(0.5)PPGER 171.36 7.572800000000001e-11 102301000.0 99959.0 68362.0 131010.0 192404.0 145666.0 109371.0 99280.0 128718.0 97934.0 112765.0 True False 131743.88272363823 90458.6796082279 129272.72179958665 148048.23041216756 125442.79027818517 102532.01408030676 108115.72766915553 108827.5907453844 103110.59130377628 108817.13167299445 1.2106906394072285 0.8312907923364917 1.1879813390786953 1.360523183583502 1.152785304570905 0.9422414697386524 0.9935542869669942 1.0000961160456001 0.9475584378903972 1.0 16.731546180234616 -6.755627957521057 24.989029864362326 0.9777500770105987 1.1449783098306214 0.32341869108234134 0.1242997821033911 195.2047524931812 839376.47908895 0.04474404665796294 0.04359900776170571 1.7553836239158061e-07 6.755627957521057 0.16722823282002275 KLCQPQSTGSLLGDPAAS(ph)SPPGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KLCQPQSTGSLLGDPAASSPPGER 24 1 U3KQ90;P55199 U3KQ90 ELL RNA polymerase II elongation factor ELL 1 KLCQPQSTGSLLGDPAAS(0.727)S(0.273)PPGER;KLCQPQSTGSLLGDPAAS(0.76)S(0.24)PPGER 159.89 6.7541e-08 51832000.0 169846.0 138144.0 166774.0 207521.0 213824.0 223570.0 199012.0 218760.0 201426.0 157855.0 True False 198597.5731885889 151858.02335810987 170750.52465391683 195894.27116215997 171926.7221484274 211845.5956275083 180160.1426378922 213017.78179537927 204371.4741894465 186472.86192050783 1.0650213180792483 0.8143706370680682 0.9156856547131597 1.0505242915490214 0.9219932615273456 1.1360666289222112 0.9661467131592225 1.1423527241523614 1.095985078389416 1.0 17.508606159493574 -6.412538623153209 1.1094476159990678 1.0723262493399868 0.9284986185063548 0.25033907060939253 0.08761611366482769 0.6075556036561612 1.573337464440395 0.0386174346788929 0.049493547680686534 3.867776557687667e-07 6.412538623153209 -0.14382763083363193 KLCQPQSTGSLLGDPAAS(ph)SPPGER ddPTM_PC-9_Lapatinib_30min_R1 1 KLCQPQSTGSLLGDPAASSPPGER 24 1 U3KQ90;P55199 U3KQ90 ELL RNA polymerase II elongation factor ELL 1 KLCQPQSTGSLLGDPAAS(0.749)S(0.251)PPGER 127.92 1.4895e-07 32410000.0 37882.0 27044.0 32513.0 29285.0 32871.0 25513.0 25508.0 23544.0 27088.0 22233.0 True False 37341.79573329203 26981.381279578414 29839.906643809398 31438.71659189618 30937.59240687251 24421.868463707804 26828.679428397445 24637.940191597718 24037.06419071434 26075.944426389684 1.4320400106199391 1.0347230703664332 1.144346151221678 1.205659748226768 1.186441875354002 0.9365669777617757 1.0288670273911908 0.9448532252071891 0.9218099178945967 1.0 14.670431885203197 -6.756313751644008 24.977107561466973 0.9668757199522775 1.18857568046494 0.5931518150569592 0.09673306664563287 92.84010506982473 452408.02720175934 0.03147816943039667 0.030564102899887965 1.752613886242255e-07 6.756313751644008 0.2216999605126626 KLCQPQSTGSLLGDPAASS(ph)PPGER ddPTM_PC-9_Lapatinib_30min_R1 1 KLCQPQSTGSLLGDPAASSPPGER 24 1 U3KQ90;P55199 U3KQ90 ELL RNA polymerase II elongation factor ELL 1 KLCQPQSTGSLLGDPAAS(0.371)S(0.629)PPGER 140.71 1.5546000000000001e-06 28515000.0 36081.0 19517.0 25343.0 17230.0 24936.0 20193.0 22087.0 20356.0 24393.0 21155.0 True False 35566.47832355496 19471.809585620907 23259.39636680903 18497.151677595048 23469.31350606226 19329.392462182102 23230.556787478996 21301.81407323152 21645.603470322447 24811.613562734372 1.4334609167448014 0.7847861057640546 0.9374398931371121 0.7455037791406164 0.9459003319845279 0.7790461677677323 0.9362775511855451 0.8585420702031902 0.8723980572884993 1.0 14.598727939981705 -4.756274461793091 24.999347029578377 0.8681997250283604 1.4334617936608103 0.8176833837344034 0.07931515889392111 58.04161294195301 280903.1331697506 0.017618200866822642 0.14476106915375314 1.752772449282051e-05 4.756274461793091 0.5652620686324499 KLDEAVAEAHLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLDEAVAEAHLGK 13 1 P23526;P23526-2 P23526 AHCY Adenosylhomocysteinase 0 62.528 0.019477 4997100.0 84428.0 80513.0 84501.0 103230.0 109560.0 104160.0 104250.0 98888.0 90755.0 86731.0 False True 98719.99287099011 88505.79854811978 86515.82431182693 97446.35777617546 88092.50448304051 98697.66623679962 94374.68529536056 96292.2947804968 92082.12018340822 102454.64373778182 0.9635482518845118 0.8638534606068015 0.8444304831438578 0.9511170428309295 0.8598195383754476 0.963330334634732 0.9211362399238752 0.9398529072722493 0.8987598494713367 1.0 16.644625850153858 -6.77029894764707 24.999765581806372 0.9393891939968034 0.8948726267936061 0.22983767554158196 0.04341206774958557 314.7315211511457 888098.1758602563 0.014691689783089932 0.013150133829062311 1.6970750646213044e-07 6.77029894764707 -0.0445165672031973 KLDELYGTWR ddPTM_PC-9_AZD4547_30min_R2 1 KLDELYGTWR 10 1 P36578;H3BM89 P36578 RPL4 60S ribosomal protein L4 0 60.641000000000005 0.042601 4806900.0 17530.0 17590.0 23734.0 30090.0 31814.0 24256.0 22881.0 27380.0 22170.0 28337.0 False True 23104.175353348677 23275.62350880211 23419.271652479885 23153.215385865773 27397.175249613305 22739.26848553931 24917.36467362962 23149.050129808005 23341.860939047943 27344.930255111514 0.8449162289975077 0.8511860623397004 0.8564392534189106 0.846709615634796 1.001910591616595 0.8315716395469218 0.9112242906149627 0.8465572928451999 0.8536083552337718 1.0 14.738985761971914 -12.067980550226215 2.0870607303267916 2.745507445406863 0.8728814308950585 0.3909996084242794 0.048060028886164285 4477775.966142 182735.39904891228 37211533.33202772 0.013185074857053666 8.551050076990075e-13 12.067980550226215 -1.8726260145118043 KLDELYGTWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLDELYGTWR 10 1 P36578;H3BM89 P36578 RPL4 60S ribosomal protein L4 0 80.834 0.010828 5789300.0 23363.0 21825.0 21457.0 27023.0 32455.0 30836.0 29029.0 30896.0 27152.0 23189.0 False True 27317.894459716423 23991.641763599884 21968.616256125642 25508.988919748062 26095.67573016688 29218.905876324436 26279.162968240027 30085.012737017936 27549.046633462644 27392.982135977018 0.9972588717837341 0.8758316872732915 0.8019797241160102 0.9312235080183335 0.9526409209712768 1.0666566250904574 0.9593392511188427 1.0982744626955128 1.0056972437944482 1.0 14.741518713084206 -6.435723983181625 2.3777240527735235 1.0277836751402316 0.8905565379514647 0.5001407851025252 0.058180704002766925 0.23826814859084788 2.654517552666643 0.020184203889670863 0.022909864263889634 3.666705388813679e-07 6.435723983181625 -0.1372271371887669 KLDFNS(ph)PGGSSPVENSDCSTNSR ddPTM_PC-9_AZD4547_30min_R2 2 KLDFNSPGGSSPVENSDCSTNSR 23 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 KLDFNS(0.973)PGGS(0.004)S(0.023)PVENSDCSTNSR;KLDFNS(1)PGGSSPVENSDCSTNSR 117.6 1.1397999999999999e-08 14690200.0 36306.0 31162.0 43500.0 53617.0 52453.0 49093.0 47345.0 57355.0 46496.0 45904.0 True False 47850.552788287365 41234.507093876746 42923.16157760493 41256.4290243923 45170.80635468559 46023.20694923241 51558.613280581914 48492.10263678373 48953.68363653469 44296.914932090156 1.0802231455993074 0.9308663404007194 0.9689876065502242 0.93136122656941 1.0197280425495807 1.0389709310408808 1.1639323722571737 1.0947060920862108 1.1051262534102801 1.0 15.434918605030429 -6.815700547204714 2.442010464338371 1.0983363793353496 0.9754047274446259 0.4365117326367727 0.05543791833438681 0.23407437905705455 2.856236563536233 0.020740050008499034 0.01854944671695916 1.52861970198752e-07 6.815700547204714 -0.12293165189072364 KLDFNS(ph)PGGSSPVENSDCSTNSR ddPTM_PC-9_Lapatinib_30min_R1 1 KLDFNSPGGSSPVENSDCSTNSR 23 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 KLDFNS(0.999)PGGS(0.001)SPVENSDCSTNSR 76.796 0.00015229 7647300.0 4440.2 4833.3 5704.5 5184.1 6835.2 5910.5 5360.4 3755.6 5779.4 4923.2 True False 4376.881933767045 4822.1087908070685 5235.498030006794 5565.356007650643 6433.16697452024 5657.721693048443 5637.935283361359 3930.098886491862 5128.463112219966 5774.168560248356 0.7580107660692864 0.8351174269494589 0.9067102865770179 0.9638367757333479 1.1141287108950522 0.9798331368430117 0.9764064253640118 0.6806345962167101 0.8881734328863069 1.0 12.495397508184176 -5.089917709512386 2.054933807819277 0.9392773603486303 0.7550884727533143 0.24970534461828076 0.10385551658844752 0.6806157648596043 4.767250953776641 0.03198104687385232 0.1844380628405093 8.129845465737139e-06 5.089917709512386 -0.18418888759531604 KLDFNSPGGSS(ph)PVENSDCSTNSR ddPTM_PC-9_AZD4547_30min_R2 1 KLDFNSPGGSSPVENSDCSTNSR 23 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 KLDFNSPGGS(0.065)S(0.934)PVENS(0.001)DCSTNSR 143.21 1.3845000000000001e-08 14891000.0 25273.0 26678.0 34236.0 38981.0 39965.0 30379.0 28576.0 29418.0 30895.0 31712.0 True False 33309.2882889436 35301.14178327589 33782.00827059499 29994.532700446434 34416.54959611479 28479.396327597224 31119.208640952755 24872.124058389025 32528.046626607436 30601.772532381565 1.088475782038346 1.1535652631206783 1.1039232526432325 0.9801567104881728 1.124658696148943 0.9306453179292629 1.0169086972992711 0.8127674314313115 1.0629464875666128 1.0 14.901327599448253 -6.315617594856061 0.8626776257106745 0.9530491538521283 1.123280104607941 0.35133726789766007 0.07839606737256417 0.6225256448616407 1.0021816659485272 0.03956289299158573 0.06133269986985798 4.834843324782191e-07 6.315617594856061 0.17023095075581274 KLDFNSPGGSS(ph)PVENSDCSTNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLDFNSPGGSSPVENSDCSTNSR 23 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 KLDFNSPGGS(0.218)S(0.782)PVENSDCSTNSR 74.471 0.0001963 6366200.0 9037.9 7555.9 12196.0 10514.0 13444.0 10238.0 13463.0 7592.7 11254.0 10325.0 True False 10567.837963338223 8305.999816796539 12486.798893587564 9924.934666847912 10809.74470856151 9701.101257031054 12187.68717632077 7393.3996701306305 11418.56845952374 12196.840767344967 0.8664405943243818 0.6809960034105295 1.023773215685402 0.8137299532039715 0.8862741520331086 0.7953782001486939 0.9992495113120846 0.6061733371091669 0.9361906642329115 1.0 13.574219888032967 -12.44777240153955 1.1956078364489056 3.0151806777187926 0.842059153435164 0.12236438776889114 0.12397575412936158 227632.29271305498 6347.970679297129 1235645.9229929862 0.033525784838691924 3.5663798588323645e-13 12.44777240153955 -2.1731215242836286 KLDFNSPGGSS(ph)PVENSDCSTNSR ddPTM_PC-9_Lapatinib_30min_R1 2 KLDFNSPGGSSPVENSDCSTNSR 23 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 KLDFNSPGGS(0.25)S(0.75)PVENSDCSTNSR;KLDFNSPGGS(0.002)S(0.998)PVENSDCSTNSR 231.41 9.166799999999999e-48 18550600.0 71369.0 93322.0 97567.0 93502.0 115894.0 105599.0 102665.0 105730.0 117570.0 97523.0 True False 70351.26497252838 93105.9186426866 89545.41787951143 100378.44899352822 109077.34277637057 101082.77693329199 107980.49135629695 110642.6017863418 104328.02853301408 114379.72060877061 0.6150676413449279 0.8140072221469237 0.7828784456100962 0.8775895627238595 0.9536423257184153 0.883747367062033 0.9440527637380592 0.9673270855835413 0.9121199805152718 1.0 16.80347176107567 -3.8382126055288848 0.4803211056486788 0.956853510318143 2.7657279576226032e-15 0.8684651236205827 0.03911784690252951 3.6433139138697284 0.3246191239252739 0.023104237978663664 2.392427770125939 0.00014514009214675015 3.8382126055288848 -0.9568535103181403 KLDPAVGSPPAPPPPPVPS(ph)PPFPCPADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLDPAVGSPPAPPPPPVPSPPFPCPADR 28 1 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 KLDPAVGSPPAPPPPPVPS(1)PPFPCPADR 113.8 2.0588e-12 3243300.0 18083.0 17745.0 24592.0 24554.0 28148.0 26307.0 30098.0 27441.0 26150.0 20897.0 True False 21144.094744469978 19506.606327380527 25178.36654567936 23178.318985142072 22632.601462108705 24927.414609173265 27246.89954935024 26720.702826142824 26532.394279060405 24685.46067943901 0.856540415390396 0.7902062910913367 1.0199674566596564 0.938946179134819 0.9168393393994803 1.0098014751628996 1.103763057257615 1.0824469987873877 1.0748186806641102 1.0 14.591373948417825 -5.663974183192515 0.5243102621206834 1.0733977434041135 0.7730310231708513 0.6366861063232192 0.058632611382207496 1.2204866128365426 0.4861746524770702 0.04308747340032857 0.20402973585805653 2.167832968678898e-06 5.663974183192515 -0.3003667202332623 KLDPEEEDDS(ph)FNNYEVQSEAK ddPTM_PC-9_Lapatinib_30min_R1 2 KLDPEEEDDSFNNYEVQSEAK 21 1 A0A087WWW8;Q9Y6J0-2;Q9Y6J0 A0A087WWW8 CABIN1 Calcineurin-binding protein cabin-1 1 KLDPEEEDDS(0.918)FNNY(0.082)EVQSEAK;KLDPEEEDDS(0.989)FNNY(0.011)EVQSEAK 78.708 0.0072295 5031700.0 50622.0 47907.0 49952.0 40420.0 44412.0 42984.0 41781.0 35619.0 43419.0 29410.0 True False 49900.12099706218 47796.07428489728 45845.13938029612 43392.62163716726 41799.77347735149 41145.67452059799 43944.21574399694 37273.98877355244 38528.69499766044 34493.479313638294 1.4466537441275833 1.385655353880155 1.3290958260093384 1.257994916738085 1.2118166769225966 1.1928537027672212 1.2739861741526881 1.0806097127701109 1.1169848842249632 1.0 15.07403603851242 -1.5228787452803376 0.13777228696526775 0.9349694845572831 2.7288667036142455 0.9048461587378862 0.04062030610785907 22.10209013556332 0.2043178477110964 0.18959195330595996 7.779961063110829 0.029999999999999995 1.5228787452803376 1.7938972190569624 KLDPGSEETQTLVR ddPTM_PC-9_AZD4547_30min_R2 1 KLDPGSEETQTLVR 14 1 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 0 59.294 0.038048 6770200.0 18900.0 20064.0 30437.0 42521.0 36029.0 22758.0 29491.0 37086.0 23770.0 34774.0 False True 24909.806855578434 26549.29562709528 30033.385492817484 32718.440392901244 31026.995255809346 21334.93866234761 32115.641868362894 31355.21085149964 25026.433672583215 33556.57284438185 0.7423227327503712 0.7911801884601648 0.8950075334598947 0.9750233000441543 0.9246175227636211 0.6357901553680138 0.9570596502002379 0.9343984857127395 0.7457982610036775 1.0 15.034307759424609 KLDPGSEETQTLVR ddPTM_PC-9_Lapatinib_30min_R1 2 KLDPGSEETQTLVR 14 1 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 0 ; 86.49799999999999 0.0040992 32371000.0 85883.0 80052.0 88156.0 77886.0 86229.0 78265.0 69315.0 67953.0 79830.0 66636.0 False True 84658.2926709866 79866.64451238026 80908.15397200074 83613.99626007963 81157.17975273666 74917.78839462594 72903.7915391003 71110.34445462271 70838.70475283239 78153.94381311111 1.0832248321777502 1.021914450067481 1.0352408339811456 1.0698627884988772 1.0384271834932242 0.9585925513084309 0.9328229387045975 0.9098753176764605 0.9063996171738743 1.0 16.254031056050877 -6.821186226085111 2.916005794533955 0.9308206083854651 1.0501873792811642 0.7798520396290264 0.028895352133820155 0.11374989052786291 1.967800663677173 0.0106142342654157 0.00952558418185682 1.5094327684784676e-07 6.821186226085111 0.11936677089569914 KLDVEEPDSANS(ph)SFYSTR ddPTM_PC-9_AZD4547_30min_R2 1 KLDVEEPDSANSSFYSTR 18 1 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 KLDVEEPDS(0.02)ANS(0.484)S(0.484)FYS(0.012)T(0.001)R 112.56 8.0577e-05 15059000.0 63949.0 70534.0 105450.0 115510.0 82722.0 106700.0 110480.0 112990.0 81591.0 112670.0 True False 84283.4517781687 93332.73613245298 104051.66410019396 88880.95411171002 71237.47818565782 100028.03213254648 120312.50597188048 95529.99175189942 85903.73368867228 108725.45759407902 0.7751951901902928 0.8584257835998815 0.9570128873466375 0.8174806165777894 0.6552051355959275 0.9200056210018086 1.1065716220856123 0.8786349937339956 0.7900976973524407 1.0 16.730330255138718 -6.975952255897466 24.999550014428664 0.9450804472367732 0.819904421509518 0.27284044142799146 0.10341348055309611 347.54175986843126 361296.3329413844 0.03865090848228077 0.03408544648984229 1.0569336966836918e-07 6.975952255897466 -0.12517602572725517 KLDVEEPDSANS(ph)SFYSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLDVEEPDSANSSFYSTR 18 1 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 KLDVEEPDS(0.008)ANS(0.451)S(0.451)FY(0.001)S(0.044)T(0.044)R 54.828 0.018961000000000002 9642300.0 55446.0 50419.0 59125.0 58852.0 60051.0 61600.0 55456.0 48617.0 55270.0 41123.0 True False 64831.912691582285 55424.26511243728 60534.76423281119 55554.713240758334 48284.43762971043 58369.58755939758 50202.806213328724 47340.85526396949 56078.219189432835 48578.274370511084 1.3345865725304107 1.1409270055521359 1.2461283365297589 1.1436123238350808 0.9939512725676599 1.2015574516749448 1.0334415304756852 0.9745273144718216 1.1543888686065495 1.0 15.568023622069061 -1.5228787571508247 0.2897561272550674 1.0257777384261924 3.2659911858496256 0.5306842727583665 0.0780118520433375 42.20768021610193 0.5988548510497764 0.08127190798711703 48.431358274856365 0.02999999918001581 1.5228787571508247 2.240213447423433 KLDVEEPDSANS(ph)SFYSTR ddPTM_PC-9_Lapatinib_30min_R1 1 KLDVEEPDSANSSFYSTR 18 1 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 KLDVEEPDS(0.022)ANS(0.475)S(0.475)FYS(0.016)T(0.011)R 72.058 0.0038554 17013000.0 77514.0 84694.0 89369.0 63244.0 72921.0 77799.0 63420.0 50857.0 49285.0 50062.0 True False 76408.63614567315 84497.89624658371 82021.42579431641 67895.1747357994 68631.93014820198 74471.71812832693 66703.57728355678 53220.00188260641 43734.004305941984 58715.149996578024 1.3013444766832125 1.439115735061706 1.3969380270525869 1.1563484848417556 1.168896445844078 1.268356090935086 1.1360539364617877 0.9064100472485913 0.7448504229060275 1.0 15.8414451827976 -7.609678421725565 1.9628278272992672 0.8517047126919749 1.292896748305996 0.7641918681449769 0.10046424303304383 0.17164517014915823 1.3077959159963148 0.0704457092198939 0.03316425751891966 2.4565272058440723e-08 7.609678421725565 0.4411920356140212 KLDVEEPDSANSS(ph)FYSTR ddPTM_PC-9_AZD4547_30min_R2 1 KLDVEEPDSANSSFYSTR 18 1 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 KLDVEEPDSANS(0.242)S(0.756)FYS(0.001)T(0.001)R 161.97 1.3017e-06 13667000.0 60676.0 53863.0 78132.0 73688.0 62935.0 82825.0 67073.0 86705.0 63276.0 74411.0 True False 79969.70586079774 71273.16140162651 77095.91862945817 56700.37006825115 54197.56158717592 77645.93965677741 73042.36706238199 73306.7345326882 66620.64017948572 71805.8935389458 1.1136927892614283 0.992580941325793 1.073671182542185 0.7896339321715733 0.7547787363411954 1.081331013792957 1.0172196662766344 1.0209013622667111 0.9277879140011297 1.0 16.13181463906396 KLDVEEPDSANSS(ph)FYSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLDVEEPDSANSSFYSTR 18 1 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 KLDVEEPDSANS(0.245)S(0.752)FYS(0.001)T(0.001)R 137.39 4.6985e-05 8158000.0 55511.0 44073.0 40540.0 46990.0 44326.0 49645.0 42422.0 44043.0 42889.0 32771.0 True False 64907.91590777375 48448.276171690166 41506.62734880617 44357.302643635485 35640.638496853404 47041.52880497232 38403.48105131689 42886.91791741587 43516.170486983654 38712.12288490675 1.6766819040316783 1.2515014047596804 1.0721868049501608 1.1458245980338553 0.9206583323475948 1.2151627267982525 0.9920272563065718 1.107842058802123 1.1240967233018866 1.0 15.240497803468765 -4.689546150166693 1.8392942337408749 1.0731604297471005 1.977262882675409 0.8378857675838672 0.08057839975183805 0.38838912229460104 1.13004384208445 0.020375886885980334 0.659914767758533 2.043872732968158e-05 4.689546150166693 0.9041024529283086 KLDVEEPDSANSS(ph)FYSTR ddPTM_PC-9_Lapatinib_30min_R1 1 KLDVEEPDSANSSFYSTR 18 1 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 KLDVEEPDSANS(0.203)S(0.659)FYS(0.069)T(0.069)R 126.26 2.0093e-05 15229000.0 130090.0 92286.0 110300.0 90701.0 83147.0 108680.0 78233.0 78220.0 73618.0 51673.0 True False 128234.89274441586 92072.31743703476 101231.55977031252 97371.454109666 78256.45693329156 104032.00974545388 82283.5219429912 81854.38675614895 65326.3656080925 60604.60920005546 2.1159264029096074 1.5192296205244813 1.6703607383416619 1.606667469601914 1.2912624628098408 1.716569269542599 1.3577106267837447 1.3506297266260407 1.0779108465570753 1.0 15.887139899603952 -1.5228787456144874 0.11923029539129512 0.785593151668007 4.309825853930873 0.710944539733312 0.16767940453051905 54.1533933676605 0.44609099520470774 1.1695396129797155 31.660612036601858 0.029999999976917744 1.5228787456144874 3.5242327022628657 up KLEAAEER ddPTM_PC-9_AZD4547_30min_R2 1 KLEAAEER 8 1 P16949;A2A2D0;P16949-2;E5RIR6;E7EVN3;Q9H169-3;Q9H169;Q9H169-4;Q9H169-2;E5RGX5;Q93045;Q93045-2 P16949;E5RGX5 STMN1;STMN4;STMN2 Stathmin;Stathmin-4;Stathmin-2 0 70.256 0.024447 1993900.0 24774.0 24919.0 36943.0 47478.0 36059.0 31589.0 28580.0 34066.0 29357.0 29930.0 False True 32651.61666878836 32973.57943239568 36453.11168187261 36532.68062778779 31052.830273647025 29613.73483631682 31123.56463320371 28801.882458803484 30908.75108649665 28882.159809982983 1.1305115989802978 1.141659060448745 1.2621324693755334 1.2648874207517002 1.0751560990571682 1.025329650938396 1.0776051665791972 0.9972205211899786 1.0701675806050068 1.0 14.817891010647228 -6.417524762347502 5.163805560210989 1.037859922620122 1.199338288882887 0.7345252158496386 0.0472479576802871 0.12767748174026164 5.100215451270347 0.015928400331900964 0.01800756680092843 3.8236245171904435e-07 6.417524762347502 0.16147836626276502 KLEAAEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLEAAEER 8 1 P16949;A2A2D0;P16949-2;E5RIR6;E7EVN3;Q9H169-3;Q9H169;Q9H169-4;Q9H169-2;E5RGX5;Q93045;Q93045-2 P16949;E5RGX5 STMN1;STMN4;STMN2 Stathmin;Stathmin-4;Stathmin-2 0 61.691 0.041054 3625600.0 34633.0 37790.0 40673.0 44810.0 46067.0 43637.0 52702.0 40190.0 42140.0 34883.0 False True 40495.68286707008 41541.54145459061 41642.798573211454 42299.44097598013 37040.50204472649 41348.59890145183 47709.68503056205 39135.055084824904 42756.217778952436 41207.01176632394 0.982737673304542 1.0081182709914447 1.010575549844739 1.0265107602524326 0.8988883313057295 1.0034359961826593 1.1578050187456774 0.9497183466433174 1.0375956893310707 1.0 15.330602226176419 -7.012804149636431 24.987390404954002 1.0390226054852596 0.9864010327741741 0.14471489757061884 0.05826323132691038 1214.833486206984 2370752.9236892774 0.021581194425817442 0.017559020294146004 9.70947729184795e-08 7.012804149636431 -0.052621572711085474 KLEAAEER ddPTM_PC-9_Lapatinib_30min_R1 1 KLEAAEER 8 1 P16949;A2A2D0;P16949-2;E5RIR6;E7EVN3;Q9H169-3;Q9H169;Q9H169-4;Q9H169-2;E5RGX5;Q93045;Q93045-2 P16949;E5RGX5 STMN1;STMN4;STMN2 Stathmin;Stathmin-4;Stathmin-2 0 65.465 0.032718000000000004 13267000.0 163850.0 138140.0 170890.0 134640.0 162980.0 152480.0 153730.0 167160.0 154650.0 137700.0 False True 161513.46895358976 137820.1453172963 156840.08385447634 144541.87474587336 153393.83683100832 145958.7858482406 161689.38719333318 174926.8638475823 137231.6884633037 161501.26152628334 1.0000755871947442 0.8533688468734772 0.9711384441969302 0.894989137421382 0.9497996200236765 0.9037625122481578 1.001164855712407 1.083130015173993 0.8497251796449286 1.0 17.301185908647682 -7.268334452952891 24.563885638174977 0.9904325171009943 0.9267590223091802 0.13802829060445942 0.06587723895739046 757.1396299219251 2697314.6764183072 0.025481302544446624 0.017617567933779464 5.39095301881752e-08 7.268334452952891 -0.06367349479181417 KLEEVLS(ph)TEGAEENGNSDK ddPTM_PC-9_AZD4547_30min_R2 2 KLEEVLSTEGAEENGNSDK 19 1 O15355 O15355 PPM1G Protein phosphatase 1G 1 KLEEVLS(0.755)T(0.245)EGAEENGNSDK;KLEEVLS(0.969)T(0.031)EGAEENGNSDK 113.67 3.8678000000000005e-05 22037000.0 125994.0 153116.0 133740.0 161855.0 153532.0 174633.0 132843.0 167117.0 144402.0 140930.0 True False 166057.47116199744 202607.7526534252 131966.5202158362 124541.83038482226 132216.73195522814 163713.170903495 144665.7696490091 141292.90761662272 152034.79491747438 135996.08359575373 1.2210459799386628 1.489805789229002 0.9703700042429505 0.9157751244882972 0.9722098494265492 1.2038079816337202 1.0637495273689341 1.0389483570469111 1.117935097082615 1.0 17.05320557989522 -5.268924247470306 24.999658175469264 1.0372456608386402 1.3554258900653617 0.6308076874130005 0.09793847017331196 324.45428098472144 1083688.1437706535 0.026335945152490305 0.05660692776815387 5.3836367929770915e-06 5.268924247470306 0.3181802292267215 KLEEVLS(ph)TEGAEENGNSDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLEEVLSTEGAEENGNSDK 19 1 O15355 O15355 PPM1G Protein phosphatase 1G 1 KLEEVLS(0.897)T(0.103)EGAEENGNSDK 99.943 0.00021706 7072500.0 54455.0 76058.0 38583.0 55244.0 62166.0 51654.0 59301.0 40858.0 42993.0 45735.0 True False 63673.15596472443 83608.5355901893 39502.96504684232 52148.85778346452 49985.018562364996 48945.173308329926 53683.5799779394 39785.5207926294 43621.69129023497 54026.39346193923 1.1785564773925026 1.5475498220900168 0.7311790129887451 0.9652478065226137 0.9251962857298383 0.9059492994440033 0.9936547035248366 0.7364089705646869 0.8074144597670727 1.0 15.721376757457065 -5.263813701644844 24.999999809572106 0.8829145917995871 1.3630531600924998 0.7061722613161325 0.12382869356213484 96.6607982440882 1017785.1581257442 0.03082198426817519 0.0694428440905629 5.447362770609601e-06 5.263813701644844 0.4801385682929127 KLEEVLS(ph)TEGAEENGNSDK ddPTM_PC-9_Lapatinib_30min_R1 2 KLEEVLSTEGAEENGNSDK 19 1 O15355 O15355 PPM1G Protein phosphatase 1G 1 KLEEVLS(0.5)T(0.5)EGAEENGNSDK;KLEEVLS(0.726)T(0.274)EGAEENGNSDK 68.771 0.0037639 20808600.0 175974.0 185435.0 173044.0 137796.0 185280.0 198080.0 204608.0 203979.0 200963.0 158172.0 True False 173464.57849032045 185005.63665059285 158816.990289157 147929.97751398067 174382.19467449537 189608.58014703236 215201.60108536715 213456.6090019504 178328.4307057932 185511.81944905783 0.9350594426030866 0.9972714256160697 0.8561017338993253 0.7974153773776271 0.9400058454085796 1.0220835562399275 1.160042533809886 1.1506361677432972 0.9612779996196565 1.0 17.50115158213098 -6.805846947421425 3.1121238037476484 1.080970750039312 0.8985873373472196 0.5171911483998558 0.07503657364492872 0.1988460610753156 3.9383444509807046 0.029148544198153645 0.026421889554585878 1.5636986188772668e-07 6.805846947421425 -0.18238341269209235 KLEEVLS(ph)TEGAEENGNSDKK ddPTM_PC-9_AZD4547_30min_R2 2 KLEEVLSTEGAEENGNSDKK 20 2 O15355 O15355 PPM1G Protein phosphatase 1G 1 KLEEVLS(0.915)T(0.085)EGAEENGNSDKK;KLEEVLS(0.982)T(0.018)EGAEENGNSDKK 83.727 0.002363 41085000.0 50004.0 54687.0 46532.0 66597.0 58675.0 55011.0 45719.0 49351.0 49252.0 40461.0 True False 65904.23185218764 72363.5032874283 45914.95527653132 51244.0905633933 50528.989054223326 51571.15347369732 49787.90243056129 41724.936923161265 51855.36017004914 39044.4727053699 1.6879273117478582 1.8533610079327807 1.175965561707189 1.3124544144847818 1.294139363477021 1.3208310908141572 1.2751587863988187 1.0686515665871117 1.3281101415135086 1.0 15.252830708583646 -5.262938361915867 24.999999208652714 1.2356131331551752 1.7706441917095272 0.7904192747575376 0.11284648931858199 50.62080841755072 844270.3605849005 0.028029735405287325 0.06381972682134512 5.458353243279599e-06 5.262938361915867 0.5350310585543521 KLEEVLS(ph)TEGAEENGNSDKK ddPTM_PC-9_Lapatinib_30min_R1 2 KLEEVLSTEGAEENGNSDKK 20 2 O15355 O15355 PPM1G Protein phosphatase 1G 1 KLEEVLS(0.913)T(0.087)EGAEENGNSDKK;KLEEVLS(0.967)T(0.033)EGAEENGNSDKK 78.736 0.0048869 110291000.0 199900.0 161535.0 132283.0 101484.0 167746.0 163249.0 169075.0 171098.0 164090.0 139193.0 True False 197049.3893428295 161160.97563218043 121407.20236714643 108947.47190069997 157879.51008132493 156267.22082200597 177828.8762096713 179047.8377039577 145608.4562556969 163252.32458698592 1.2070234824609523 0.9871894690621011 0.7436782457725856 0.6673563281645607 0.9670888943281283 0.9572128373506984 1.0892884781859171 1.096755211032572 0.8919227130399124 1.0 17.316744009217643 -6.792885751999947 2.79674926143574 1.0246768095423637 0.8918791608342276 0.09471176733018694 0.14613596424221348 0.5895626613667649 9.443230548478713 0.059641517002809716 0.054344660638292935 1.6110693966032217e-07 6.792885751999947 -0.13279764870813615 KLEEVLST(ph)EGAEENGNSDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLEEVLSTEGAEENGNSDK 19 1 O15355 O15355 PPM1G Protein phosphatase 1G 1 KLEEVLS(0.421)T(0.579)EGAEENGNSDK 74.819 0.0035919000000000003 7686600.0 44626.0 54089.0 34686.0 49922.0 47847.0 31730.0 54792.0 28912.0 41880.0 33709.0 True False 52180.30039632347 59458.5984582522 35513.045787387535 47125.03218930774 38471.72382256343 30066.022942527383 49601.705100272404 28153.09063479616 42492.4157708241 39820.17485970281 1.3103985750983944 1.49317773384323 0.8918355058085392 1.1834461389318833 0.9661364862939367 0.7550449752784378 1.2456425737715255 0.7070057008535766 1.0671077141307468 1.0 15.281211935833184 -5.262092103027357 24.99995574701762 0.9752118930257382 1.4017881773448355 0.5169684534290656 0.16422536904417223 40.598971099027295 1555056.939986015 0.040376763430743055 0.0930261698799507 5.4689996675239545e-06 5.262092103027357 0.42657628431909733 KLEGNSPQGS(ph)NQGVK ddPTM_PC-9_AZD4547_30min_R2 1 KLEGNSPQGSNQGVK 15 1 P61006 P61006 RAB8A Ras-related protein Rab-8A 1 KLEGNS(0.004)PQGS(0.996)NQGVK 96.455 0.0012107 3045000.0 9151.2 9363.6 14810.0 14544.0 15018.0 11583.0 10297.0 11226.0 12140.0 12971.0 True False 12061.091243215315 12390.200584822029 14613.609723317912 11191.10550256005 12933.009929549657 10858.713178924865 11213.41305206784 9491.279647816822 12781.695615698796 12516.889238065127 0.9635853616517046 0.9898785831820078 1.1675113077518051 0.8940804132489059 1.0332447370564777 0.8675249075387214 0.8958626092149731 0.7582778330380108 1.0211559256135596 1.0 13.611588440346635 -6.760615734424248 24.999980372114692 0.8926627581005739 1.0109095378702808 0.2160690815884344 0.09385475318662047 29.76343015543107 903413.9412099086 0.030958495482129682 0.02926243819286798 1.7353387536689835e-07 6.760615734424248 0.11824677976970688 KLEGNSPQGS(ph)NQGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KLEGNSPQGSNQGVK 15 1 P61006 P61006 RAB8A Ras-related protein Rab-8A 1 KLEGNS(0.001)PQGS(0.999)NQGVK;KLEGNS(0.283)PQGS(0.717)NQGVK 82.265 0.0036551 9116600.0 38690.0 33614.0 33167.0 32011.0 55324.0 37660.0 39230.0 39494.0 36522.0 29932.0 True False 45239.45283766758 36950.97577281314 33957.82706654795 30217.52745106226 44483.65934665703 35685.04330335899 35513.850399395655 38457.32434735194 37056.06515716423 35358.43465841838 1.2794529303886097 1.0450399213025001 0.9603883032322823 0.8546059163246318 1.2580777338248499 1.0092370787365397 1.0043954361237615 1.0876421628635575 1.048012037725818 1.0 15.109766786616893 -4.76396046344088 5.489770920544714 1.029684426047969 1.2912317295493367 0.37668149839175924 0.09657216399502311 0.1637336580415958 15.61991884817101 0.024311778099833942 0.1627446491494811 1.722025334651096e-05 4.76396046344088 0.2615473035013678 KLENCNYAVELGK ddPTM_PC-9_AZD4547_30min_R2 1 KLENCNYAVELGK 13 1 A0A0A0MSQ0;P13797-3;P13797-2;P13797;P13796 A0A0A0MSQ0;P13796 PLS3;LCP1 Plastin-3;Plastin-2 0 101.61 0.0012397999999999999 8543900.0 81793.0 58691.0 74043.0 67318.0 97162.0 78948.0 66241.0 78146.0 70539.0 71497.0 False True 107801.47259991152 77661.71798494065 73061.14144116329 51798.87515273223 83672.73343820091 74011.36907966498 72136.32067417934 66070.33131643446 74267.5475317773 68993.9117919932 1.5624780476995936 1.1256314646874879 1.058950558730924 0.7507745800658244 1.2127553180411377 1.0727231890083098 1.0455461764751077 0.9576255295630588 1.0764362478197111 1.0 16.074181439773234 -4.724431092504472 2.4940934497885716 1.0213248113726996 1.7335577600724048 0.6817034156226079 0.11049189140390764 0.3807883994307736 2.6071468047906143 0.02878821780600366 0.6208225628866224 1.8861182073974412e-05 4.724431092504472 0.7122329486997052 KLENS(ph)PLGEALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KLENSPLGEALR 12 1 D6RI08;D6RDK1;D6RIV2;D6R9T5;D6RG39;D6RIT9;D6RDK6;D6RBN5;Q9NX40-3;Q9NX40-2;Q9NX40-4;Q9NX40 D6RI08 OCIAD1 OCIA domain-containing protein 1 1 KLENS(1)PLGEALR;KLENS(1)PLGEALR 58.885 0.030444 22743700.0 178709.0 145620.0 163339.0 178983.0 200757.0 183469.0 180591.0 174393.0 154879.0 151242.0 True False 208960.90403635942 160076.19123094677 167233.62122660686 168955.16278071553 161420.10699618247 173847.56266128426 163484.11311438354 169815.3685346573 157143.8123727191 178660.97736898682 1.1695945422082543 0.8959773621989258 0.9360388803942389 0.9456746810008435 0.9034995183240437 0.9730583881349677 0.9150521592453922 0.9504894187606464 0.8795642713191448 1.0 17.44686503380784 -4.756142183592962 24.999980773855764 0.9319336530348712 1.1695949136960497 0.8071942139469805 0.03464558000365163 63.56447984761384 299958.5552909467 0.007826729605981497 0.06524794450953468 1.7533063932009073e-05 4.756142183592962 0.23766126066117854 KLENS(ph)PLGEALR ddPTM_PC-9_Lapatinib_30min_R1 1 KLENSPLGEALR 12 1 D6RI08;D6RDK1;D6RIV2;D6R9T5;D6RG39;D6RIT9;D6RDK6;D6RBN5;Q9NX40-3;Q9NX40-2;Q9NX40-4;Q9NX40 D6RI08 OCIAD1 OCIA domain-containing protein 1 1 KLENS(1)PLGEALR 62.468999999999994 0.02363 5971200.0 59130.0 56508.0 33496.0 33563.0 35764.0 33580.0 33871.0 37898.0 55460.0 25261.0 True False 58286.79535688601 56377.159197841174 30742.08817829916 36031.334982885826 33660.431834729316 32143.861678803296 35624.674647924185 39658.87943345098 49213.51078030928 29627.33019183329 1.9673320201140716 1.9028767976326606 1.0376260020477022 1.2161519363907378 1.1361277447809908 1.0849395295045412 1.202426084876998 1.3385910636113565 1.6610848990326803 1.0 14.854641006100348 -5.250473617433559 23.681166273445307 1.2146099387794733 1.9351047361344007 0.726287293306467 0.1781274590814897 183.71442702607155 396736.8743996461 0.0468668500316916 0.12112038818024154 5.617284012546311e-06 5.250473617433559 0.7204947973549274 KLEVNEAELLR ddPTM_PC-9_Lapatinib_30min_R1 2 KLEVNEAELLR 11 1 Q6NZI2 Q6NZI2 PTRF Polymerase I and transcript release factor 0 ; 84.68700000000001 0.0075126 6568400.0 31266.0 24203.4 30701.7 25409.6 26512.4 28596.4 27310.1 25330.8 33067.1 26315.2 False True 30820.141106517836 24147.358514352454 28177.524737989213 27278.306747940773 24952.992757383912 27373.39863346427 28724.083348654414 26507.761442631814 29342.734986000083 30863.747257200088 0.9985871401058704 0.7823858299876146 0.9129651206373129 0.8838300327118289 0.8084887602740047 0.8869110547514101 0.9306738779735659 0.8588640005937036 0.9507184834516433 1.0 14.913625613887717 -8.47028169470917 3.481316067128698 0.9996033769321894 0.8798960160236836 0.3085889931950083 0.05743757521862472 0.23593661645024103 6.096070328047393 0.051903091053440015 0.013728645268407724 3.3862444425979506e-09 8.47028169470917 -0.11970736090850576 KLFAPQQILQCS(ph)PAN ddPTM_PC-9_AZD4547_30min_R2 1 KLFAPQQILQCSPAN 15 1 K7ERV3;P04183 K7ERV3 TK1 Thymidine kinase;Thymidine kinase, cytosolic 1 KLFAPQQILQCS(1)PAN 70.281 0.035311 27506000.0 22880.0 31058.0 35942.0 51961.0 36366.0 32523.0 26229.0 42636.0 34494.0 39231.0 True False 30155.36406643571 41096.89112770758 35465.38559591438 39982.194239447344 31317.208622852755 30489.33166866732 28563.330187694202 36047.58587781206 36317.282419103314 37857.53463098705 0.7965485433843603 1.0855670219494182 0.9368118114824451 1.0561225031996992 0.8272384593480389 0.8053702378102369 0.7544952534842198 0.9521905277029445 0.9593145135599238 1.0 15.208292842058075 KLFAPQQILQCS(ph)PAN ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KLFAPQQILQCSPAN 15 1 K7ERV3;P04183 K7ERV3 TK1 Thymidine kinase;Thymidine kinase, cytosolic 1 KLFAPQQILQCS(1)PAN;KLFAPQQILQCS(1)PAN 80.53399999999999 0.01432 29462000.0 78624.0 81332.0 81328.0 72583.0 92382.0 76663.0 72774.0 66192.0 57432.0 54489.4 True False 91933.49030521544 89406.10345553761 83267.16795815773 68516.40982726104 74280.41026973605 72642.65732250156 65880.31988186653 64454.53013622124 58271.834349330726 64367.89688214692 1.4282506460252877 1.3889859353216696 1.2936133071213132 1.0644500309324967 1.1539977825551493 1.1285541526314764 1.023496542111493 1.0013459077936466 0.9052934330916909 1.0 15.974053711419216 -4.892870137096886 0.3958449215280723 0.9549232560484853 1.8042644103295593 0.8920139464856852 0.055201487370036 1.6568728499426182 0.219359939948312 0.049351962193295205 0.6666301962657654 1.2797639224499384e-05 4.892870137096886 0.849341154281074 KLFAPQQILQCS(ph)PAN ddPTM_PC-9_Lapatinib_30min_R1 1 KLFAPQQILQCSPAN 15 1 K7ERV3;P04183 K7ERV3 TK1 Thymidine kinase;Thymidine kinase, cytosolic 1 KLFAPQQILQCS(1)PAN 75.961 0.021206 14299000.0 73574.0 88873.0 104310.0 81508.0 84612.0 70404.0 71795.0 65573.0 76272.0 57003.0 True False 72524.82126818091 88667.22002884082 95734.03444824404 87502.37022271706 79635.28851359246 67392.98503973997 75512.193804367 68619.76096600558 67681.44418023339 66855.89259827702 1.084793253811856 1.3262439043574434 1.431946096711171 1.3088206113483576 1.1911483852605804 1.0080335841851702 1.1294770119681727 1.0263831399025254 1.0123482246646072 1.0 16.028767102884643 -6.554213543822308 3.183387287508335 1.0427526693391689 1.2992877408088521 0.6481922437716885 0.08777430311724455 0.16327631980787236 3.420366793645128 0.03142546360345844 0.032752632543757175 2.791171077073855e-07 6.554213543822308 0.25653507146968324 KLFTCIMS(ph)S(ph)REK ddPTM_PC-9_AZD4547_30min_R2 1 KLFTCIMSSREK 12 2 A0A087X172 A0A087X172 OR4C3 2 KLFTCIMS(1)S(1)REK 100.02 0.00386 4537100.0 2110.0 741.6 24987.0 52545.0 30356.0 8734.2 4416.2 33128.0 4896.5 11100.0 True False 2780.936109273571 981.3076972215839 24655.65605378424 40431.562062157405 26141.593382701372 8188.049093271658 4809.233244686997 28008.828805707817 5155.3189935971295 10711.392378577051 0.25962414698162734 0.09161345813306347 2.3018161581958227 3.7746317783130743 2.4405411041598066 0.7644243440888117 0.4489830149725013 2.6148634851362464 0.48129307669727855 1.0 13.386858408386596 -6.775059809963951 24.996889679898803 1.1245336847657033 1.820707955289398 0.08621928544298307 1.1444049143162864 746.3485898628585 1369727.5570159536 0.44992986239628174 0.39890361131311397 1.678572833296938e-07 6.775059809963951 0.6961742705236948 KLFTCIMS(ph)S(ph)REK ddPTM_PC-9_Lapatinib_30min_R1 1 KLFTCIMSSREK 12 2 A0A087X172 A0A087X172 OR4C3 2 KLFT(0.035)CIMS(0.965)S(1)REK 68.46300000000001 0.042044 1906000.0 1049.4 1184.6 8055.8 1076.3 3490.5 3967.6 1224.5 1504.9 6098.0 0.0 True False 1034.4353635636098 1181.857131481607 7393.483220287263 1155.4546924315478 3285.1956525870364 3797.9149969273326 1287.8986184754856 1574.8231479075519 5411.1790252132305 0.0 0.0 KLGAGEGGEAS(ph)VSPEKTSTTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLGAGEGGEASVSPEKTSTTSK 22 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 KLGAGEGGEAS(0.461)VS(0.373)PEKT(0.041)S(0.041)T(0.053)T(0.022)S(0.009)K 46.861999999999995 0.018249 25712000.0 82654.0 33413.0 55796.0 124880.0 100490.0 111290.0 113170.0 135730.0 128540.0 96388.0 True False 96645.68970908698 36730.02182117585 57126.388247508374 117883.37846642238 80799.70587350102 105453.756485152 102449.71832015316 132167.23131782224 130419.65432621124 113862.38139301204 0.8487938555887108 0.3225825893663422 0.501714328723976 1.035314535180248 0.7096259966196339 0.9261509832748317 0.8997679221773304 1.160762928904749 1.1454147781790145 1.0 16.796931653070544 -6.44943514860567 0.6736042638802626 1.0994896486624268 0.5326295017235624 0.5137430281940478 0.1802124093651611 0.6239597371627066 0.6252512267913726 0.12537403143353407 0.18513444479447055 3.55275166289072e-07 6.44943514860567 -0.5668601469388644 KLGAGEGGEASVS(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 3 KLGAGEGGEASVSPEK 16 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 KLGAGEGGEAS(0.009)VS(0.991)PEK;KLGAGEGGEAS(0.002)VS(0.998)PEK;KLGAGEGGEAS(0.08)VS(0.92)PEK 126.55 1.2726e-05 284773000.0 552590.0 543910.0 496790.0 408330.0 458010.0 548560.0 603730.0 534380.0 538590.0 509520.0 True False 728302.125413973 719718.2707602374 490202.24000318063 314195.82713561185 394423.2173280747 514258.45648200175 657460.8004200162 451803.8498307826 567058.7678467229 491681.85988581716 1.4812466857799187 1.4637885378308992 0.996990696620412 0.6390226135423773 0.8021919243058331 1.0459170826465463 1.33716708721509 0.9188946892116472 1.1533042280193344 1.0 18.90736560377566 -5.263142348042682 6.424787690715916 0.9786387628252855 1.4759596447241266 0.5457886469017323 0.1772504183594473 0.10723822967699534 24.496430198800297 0.050925508434270586 0.12055628025588244 5.4557900817886955e-06 5.263142348042682 0.49732088189884105 KLGAGEGGEASVS(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KLGAGEGGEASVSPEK 16 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 KLGAGEGGEAS(0.178)VS(0.822)PEK;KLGAGEGGEAS(0.025)VS(0.975)PEK;KLGAGEGGEAS(0.003)VS(0.997)PEK 128.38 9.7094e-06 123760100.0 275124.0 345837.0 285296.0 299136.0 279263.0 229679.0 309171.0 255612.0 219737.0 215267.0 True False 321697.0592533073 380169.4118028905 292098.53863110446 282376.3797319967 224543.41985621932 217634.2289132284 279884.0846757983 248902.45584330082 222950.23792343753 254293.203047365 1.26506353845953 1.4950042205102887 1.1486682897171174 1.1104362065052948 0.8830099159763839 0.8558397405246083 1.1006353348094275 0.9788010566563979 0.8767447782782873 1.0 17.9561333754703 -5.6630033917968925 1.8762264248039588 0.9552979528145875 1.3786450950924518 0.7479236904678437 0.09510458599444842 0.16268555874958157 1.153840135704607 0.028629577917911514 0.06490056222765869 2.1726842103489764e-06 5.6630033917968925 0.4233471422778643 KLGAGEGGEASVS(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 4 KLGAGEGGEASVSPEK 16 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 KLGAGEGGEAS(0.071)VS(0.929)PEK;KLGAGEGGEASVS(1)PEK;KLGAGEGGEAS(0.007)VS(0.993)PEK;KLGAGEGGEAS(0.016)VS(0.984)PEK 118.46 5.7413999999999996e-05 331405000.0 282761.0 365048.0 327582.0 337134.0 379199.0 337469.0 377741.0 338498.0 301294.0 302234.0 True False 278728.77628798294 364202.75378448266 300649.4724630876 361927.95900605555 356895.26035391825 323036.2375486622 397298.5806790924 354225.85282770277 267359.09695352474 354474.74419850844 0.7863149091713366 1.0274434490614273 0.8481548470903802 1.0210260813486143 1.0068284587125742 0.9113096005727266 1.1208092739509878 0.9992978586630524 0.7542401858785226 1.0 18.435323315674367 -4.749448622752636 24.627752671094058 0.9679611029046409 0.7863144100573326 0.23005413765535954 0.09822185906684641 690.1510295540929 1417391.156888799 0.023884753448889556 0.3833635871937257 1.7805385349651846e-05 4.749448622752636 -0.18164669284730828 KLGAGEGGEASVS(ph)PEKTSTTSK ddPTM_PC-9_AZD4547_30min_R2 4 KLGAGEGGEASVSPEKTSTTSK 22 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 KLGAGEGGEAS(0.102)VS(0.884)PEKT(0.004)S(0.004)T(0.005)T(0.002)S(0.001)K;KLGAGEGGEAS(0.007)VS(0.77)PEKT(0.136)S(0.054)T(0.022)T(0.009)S(0.004)K;KLGAGEGGEAS(0.254)VS(0.738)PEKT(0.002)S(0.002)T(0.001)T(0.001)S(0.001)K;KLGAGEGGEAS(0.254)VS(0.744)PEKT(0.001)STTSK 62.847 0.0014983 307278000.0 436042.0 259271.0 417682.0 727792.0 565947.0 442295.0 379096.0 386283.0 341105.0 460164.0 True False 574694.2857629699 343075.28042925766 412143.2637714291 560010.7986743108 487375.02800631436 414638.2237306895 412834.8095937365 326591.83825027855 359135.1139203408 444053.7984230214 1.2941996843713421 0.772598459122811 0.928138133791633 1.2611327741437866 1.097558515966175 0.9337567321869645 0.9296954807274397 0.7354780871374409 0.8087648730756176 1.0 18.76037494834617 -7.15502263828722 2.16580013414306 0.8373061610600593 1.0539179546124384 0.26484092769443734 0.1560668012253791 0.45259702488500836 4.160634999056042 0.07450573936136812 0.05230186759650747 6.998055165813851e-08 7.15502263828722 0.21661179355237914 KLGAGEGGEASVS(ph)PEKTSTTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLGAGEGGEASVSPEKTSTTSK 22 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 KLGAGEGGEAS(0.118)VS(0.638)PEKT(0.032)S(0.091)T(0.042)T(0.054)S(0.025)K 43.476000000000006 0.034480000000000004 89226000.0 213450.0 91212.0 147550.0 273440.0 253840.0 292790.0 278160.0 366290.0 270580.0 223740.0 True False 249582.86917033218 100266.92456089244 151068.1515864913 258120.0433044414 204101.8742056871 277435.5769726627 251810.67109599547 356675.2756163356 274536.7206129321 264302.29087513394 0.9443083839490602 0.37936456861156076 0.5715733718625292 0.9766091790191359 0.7722289259388686 1.0496903982710215 0.9527373760636831 1.3494974804620292 1.0387224405203257 1.0 18.011829404220954 -6.449794126845424 0.9478305081019206 1.124297722257175 0.6206073597942658 0.48328833042030417 0.1845919065564511 0.4396144879645382 0.8550457141102893 0.09411245949243383 0.12082014374330977 3.549816250068086e-07 6.449794126845424 -0.5036903624629092 KLGAGEGGEASVS(ph)PEKTSTTSK ddPTM_PC-9_Lapatinib_30min_R1 2 KLGAGEGGEASVSPEKTSTTSK 22 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 KLGAGEGGEAS(0.115)VS(0.594)PEKT(0.087)S(0.087)T(0.04)T(0.052)S(0.024)K;KLGAGEGGEAS(0.062)VS(0.935)PEKT(0.001)S(0.001)T(0.001)T(0.001)SK 64.295 0.001032 210046000.0 477200.0 199703.0 272987.0 228353.0 207911.0 198172.0 149086.0 141255.0 231003.0 167368.0 True False 470395.0404922372 199240.59997321613 250543.06262029306 245146.84138327747 195682.0837487532 189696.64552149503 156804.94359659954 147818.2229767299 204985.0095705695 196297.33579615786 2.396339403101793 1.0149939079158703 1.2763446921178079 1.2488546540328325 0.996865713714813 0.9663740200655743 0.7988134070216387 0.753032242527375 1.0442577263678874 1.0 17.582681066702158 -2.9434131898381692 1.3604442569133584 0.9794240527913864 199.99999841329986 0.8533470958999492 0.16993304732828524 78.37816428673634 1.343238511562857 0.05292807288163024 47598.072973205846 0.0011391654643803865 2.9434131898381692 199.02057436050848 up KLGDVS(ph)PTQIDVSQFGSFK ddPTM_PC-9_AZD4547_30min_R2 1 KLGDVSPTQIDVSQFGSFK 19 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 KLGDVS(0.929)PT(0.07)QIDVSQFGSFK 71.678 0.0028160999999999998 1403000.0 6265.4 6525.2 8063.3 7779.7 9504.2 5974.6 6265.9 7284.8 9337.6 7802.4 True False 8257.666871584188 8634.343292759271 7956.375373533374 5986.210360166834 8184.705884433733 5601.007317517443 6823.552961343286 6159.1015480505985 9831.166472911787 7529.240350865727 1.096746349800708 1.1467748259313408 1.0567301617112719 0.7950616637545018 1.087055998085204 0.7439007199276655 0.9062737598167789 0.8180242974103507 1.305731523337727 1.0 12.878288598785915 -5.535322663661398 23.947203234593644 0.9375072827024016 1.1167586043702489 0.16972167299753926 0.1536836639017916 198.10739873852128 381238.0013524554 0.04014492295247804 0.0696039263958445 2.915260285857233e-06 5.535322663661398 0.1792513216678473 KLGDVS(ph)PTQIDVSQFGSFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLGDVSPTQIDVSQFGSFK 19 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 KLGDVS(0.827)PT(0.173)QIDVSQFGSFK 65.47 0.0048405 99235000.0 28510.0 43155.0 37437.0 35083.0 45553.0 27072.0 36618.0 28181.0 30296.0 29421.0 True False 33336.17990183261 47439.14319854079 38329.640060613136 33117.41325062064 36627.2166549466 25652.29666246773 33149.27794863802 27441.27861023763 30739.021685599022 34754.79440349216 0.959182192672761 1.3649668775993136 1.1028590650146897 0.9528876179251113 1.053875221637516 0.7380937537610692 0.9538044611567945 0.7895681468189129 0.884454136851702 1.0 15.084924390048377 -6.004860517048407 1.4111328093360067 0.87500478731985 1.1724143714814572 0.4187305257758692 0.12641259224167387 0.354184134775319 1.4289633931738968 0.04287607822912813 0.0764557777738525 9.888706405943912e-07 6.004860517048407 0.29740958416160723 KLGDVS(ph)PTQIDVSQFGSFK ddPTM_PC-9_Lapatinib_30min_R1 4 KLGDVSPTQIDVSQFGSFK 19 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 KLGDVS(0.987)PT(0.013)QIDVSQFGSFK;KLGDVS(0.869)PT(0.131)QIDVSQFGSFK;KLGDVS(0.908)PT(0.091)QIDVS(0.001)QFGSFK;KLGDVS(0.852)PT(0.148)QIDVSQFGSFK 142.56 9.852e-05 349405870.0 571770.3 826402.8999999999 907450.1 822382.7 922884.7 870933.1 825307.7 957138.3 903090.0 786904.6 True False 563616.7506721687 824489.4148590933 832843.0556366862 882863.4671462665 868602.4364071301 833685.3215572162 868038.0944444108 1001610.4396231517 801374.4942407039 922920.0116255297 0.6106886226028149 0.8933487241293299 0.9024000402481338 0.9565980323595844 0.9411459557337687 0.9033126501275606 0.9405344813312088 1.0852624572079927 0.8683033027198652 1.0 19.81584609107084 -4.346515675908317 1.4417883311591038 0.9540656924144875 5.097383944451939e-16 0.7617087385585495 0.05663310261847954 1.7058772581845263 1.3976127233760447 0.015689085753850262 3.1912539727396796 4.5028172802498984e-05 4.346515675908317 -0.9540656924144869 KLGDVS(ph)PTQIDVSQFGSFKEDTK ddPTM_PC-9_AZD4547_30min_R2 4 KLGDVSPTQIDVSQFGSFKEDTK 23 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 KLGDVS(0.79)PT(0.21)QIDVSQFGSFKEDTK;KLGDVS(0.885)PT(0.112)QIDVS(0.003)QFGSFKEDTK;KLGDVS(0.844)PT(0.156)QIDVSQFGSFKEDTK;KLGDVS(0.835)PT(0.165)QIDVSQFGSFKEDTK 100.59 1.5312000000000002e-05 244396400.0 208104.0 160500.9 212752.0 320234.0 306765.0 261081.0 173724.4 229926.0 221762.0 238102.0 True False 274276.7431678996 212379.67715883447 209930.7694703128 246408.99886597993 264175.97489934054 244755.56379753776 189185.53505124387 194396.21987385844 233483.8865839042 229766.12145260847 1.1937214304436605 0.92432981771266 0.9136715549842848 1.0724339920444026 1.1497603442543616 1.065237826404364 0.823383072557393 0.8460612846004566 1.0161806497310901 1.0 17.809806565651904 -7.242937827100512 24.60928176805197 0.9085780219561519 1.0462573094841072 0.29563933717294 0.09851505133788686 864.8950208211135 1150415.287176909 0.03941756492618105 0.03047196017899348 5.7156045449061164e-08 7.242937827100512 0.13767928752795533 KLGDVS(ph)PTQIDVSQFGSFKEDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 KLGDVSPTQIDVSQFGSFKEDTK 23 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 KLGDVS(0.5)PT(0.5)QIDVSQFGSFKEDTK;KLGDVS(0.845)PT(0.155)QIDVSQFGSFKEDTK;KLGDVS(0.963)PT(0.036)QIDVS(0.001)QFGSFKEDTK;KLGDVS(0.978)PT(0.022)QIDVSQFGSFKEDTK;KLGDVS(0.749)PT(0.248)QIDVS(0.002)QFGSFKEDTK 104.95 7.1629e-06 238253900.0 208488.7 131886.4 164337.0 256081.4 281570.3 295788.4 253373.1 281806.1 253443.7 216359.2 True False 243781.71907047337 144979.21018514704 168255.41733154273 241733.98938510052 226398.62098431133 280276.7355982811 229371.76570561092 274408.98847324355 257149.8346441268 255583.41026151457 0.9538245022281938 0.567248124738626 0.6583190088878723 0.9458125202170077 0.8858110968652418 1.0966155248945937 0.8974438734928698 1.0736572776475066 1.0061288186937072 1.0 17.963434669445533 -5.84645847160035 4.862649970826858 0.9902694215214723 0.7110517871726735 0.5398653393144828 0.11015225015244375 0.1464441935863296 6.028691626292239 0.030665303483263937 0.047021027805553194 1.424103416712382e-06 5.84645847160035 -0.27921763434879887 KLGDVS(ph)PTQIDVSQFGSFKEDTK ddPTM_PC-9_Lapatinib_30min_R1 8 KLGDVSPTQIDVSQFGSFKEDTK 23 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 KLGDVS(0.912)PT(0.088)QIDVSQFGSFKEDTK;KLGDVS(0.5)PT(0.5)QIDVSQFGSFKEDTK;KLGDVS(0.805)PT(0.195)QIDVSQFGSFKEDTK;KLGDVS(0.991)PT(0.009)QIDVSQFGSFKEDTK;KLGDVS(0.787)PT(0.213)QIDVSQFGSFKEDTK;KLGDVS(0.964)PT(0.035)QIDVS(0.001)QFGSFKEDTK;KLGDVS(0.533)PT(0.465)QIDVS(0.002)QFGSFKEDTK;KLGDVS(0.548)PT(0.451)QIDVSQFGSFKEDTK 99.171 1.8515e-05 308102500.0 561738.0 316595.2 388460.3 350249.6 323241.2 344502.2 260755.9 257832.4 367206.4 252605.7 True False 553727.5131098662 315862.1432659515 356522.5936341221 376008.1239824134 304228.7881326506 329768.64397985156 274256.5646135826 269812.2345674527 325847.7483771829 296268.2586690622 1.8690072152764474 1.06613561872916 1.2033776255200028 1.2691475140521964 1.0268693295034363 1.1130745003237419 0.925703502108651 0.9107024687002955 1.0998402253451038 1.0 18.17654454280919 -2.855100390046872 1.4325035125507186 1.0562038684593704 199.99999998173965 0.8131704380980521 0.11355084528066184 152.84616518954934 1.6769554253028078 0.034498219060894404 98670.02148679346 0.0013960456185612338 2.855100390046872 198.94379611328029 KLGDVSPT(ph)QIDVSQFGSFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLGDVSPTQIDVSQFGSFK 19 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 KLGDVS(0.19)PT(0.81)QIDVSQFGSFK 97.04899999999999 0.00053121 513210000.0 1000300.0 1255700.0 1273500.0 1292000.0 1375400.0 1036600.0 1320800.0 978900.0 1086300.0 932130.0 True False 1169631.0331744351 1380357.5973678092 1303865.069775643 1219613.4287205152 1105900.2433915138 982238.871169993 1195684.2622360897 953204.9122302857 1102185.0824223065 1101117.7902629795 1.0622215384378566 1.2535966720128453 1.1841286021400503 1.1076139532985254 1.0043432711475784 0.8920379634729226 1.08588224875608 0.8656702495040356 1.0009692806426025 1.0 20.07053737640871 -6.179063805662698 2.5084543642951798 0.9663768672225359 1.1735466021063607 0.6005948337840956 0.07203710539057899 0.18339243230932445 2.260728300265726 0.022176438013375013 0.029763441677963923 6.621192193453952e-07 6.179063805662698 0.20716973488382484 KLGDVSPT(ph)QIDVSQFGSFKEDTK ddPTM_PC-9_AZD4547_30min_R2 2 KLGDVSPTQIDVSQFGSFKEDTK 23 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 KLGDVS(0.254)PT(0.745)QIDVS(0.001)QFGSFKEDTK;KLGDVS(0.2)PT(0.8)QIDVS(0.001)QFGSFKEDTK 66.972 0.00072699 478576100.0 66881.0 53364.0 80147.0 117380.0 102481.0 84925.0 67633.0 74329.0 65527.0 85508.0 True False 88147.76678877987 70612.86941010338 79084.19841288049 90319.85450292214 88253.28210082413 79614.62632480313 73652.20597751805 62843.160960500405 68990.62344397811 82514.39094660975 1.0682714345648525 0.8557642927497683 0.9584291601213085 1.0945951786926822 1.069550184984431 0.9648574680302386 0.8925983108228248 0.7616024337035044 0.8361041347153361 1.0 16.332358134504545 -7.278560930808868 3.109520309759168 0.8472195011402734 1.0029579599293859 0.354769187590826 0.08524461764880126 0.27378618835205154 5.423262440932244 0.03929750226557467 0.02656559823279023 5.2654933569677004e-08 7.278560930808868 0.1557384587891124 KLGDVSPT(ph)QIDVSQFGSFKEDTK ddPTM_PC-9_Lapatinib_30min_R1 3 KLGDVSPTQIDVSQFGSFKEDTK 23 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 KLGDVS(0.28)PT(0.703)QIDVS(0.017)QFGSFKEDTK;KLGDVS(0.176)PT(0.824)QIDVSQFGSFKEDTK;KLGDVS(0.28)PT(0.719)QIDVS(0.001)QFGSFKEDTK 104.01 2.3381999999999997e-05 59021200.0 319366.0 180184.3 222981.0 186902.4 186688.0 197926.6 164778.0 148057.9 218863.3 154363.1 True False 314811.7822754477 179767.09432384078 204648.3629115512 200647.82598412875 175707.37888272997 189461.74070743957 173309.3985750539 154937.21054593762 194212.61042127776 181044.55615909872 1.7388635646066968 0.9929439367724743 1.1303756779723875 1.1082787035463415 0.9705200896972648 1.0464923371733088 0.9572748402484563 0.8557960196813738 1.07273377637827 1.0 17.465985271409153 -4.76039276077282 24.999967301647047 1.0147494520897828 1.7388644212441988 0.8909917733635785 0.07596430604085602 8.324009439065945 198736.5046864633 0.020226566194254836 0.12017863269492315 1.7362299327668636e-05 4.76039276077282 0.724114969154416 KLGEMWSEQSAK ddPTM_PC-9_AZD4547_30min_R2 1 KLGEMWSEQSAK 12 1 P26583 P26583 HMGB2 High mobility group protein B2 0 63.727 0.029314999999999997 1512600.0 5792.9 4765.9 23014.0 37368.0 24692.0 12370.0 7947.3 31232.0 10045.0 14648.0 False True 7634.921700194723 6306.383972745881 22708.819322919535 28753.38492984488 21263.942014944754 11596.50194451357 8654.594304039883 26405.812039962155 10575.958192726064 14135.1779785042 0.5401362269230273 0.44614818308875864 1.6065464019946218 2.034172118212522 1.5043278582895443 0.820400136605901 0.6122734582614517 1.868091939140652 0.7482012754851229 1.0 13.787002428059102 -5.2496551975505605 24.47826870139393 1.3007608921309808 0.4931420222525724 0.316127294907095 0.4582203087694659 687.0966758805292 1427237.6345071055 0.12317057981916146 0.3199919499978941 5.627879660427438e-06 5.2496551975505605 -0.8076188698784084 KLGPGRPLPTFPTSECTS(ph)DVEPDTR ddPTM_PC-9_AZD4547_30min_R2 2 KLGPGRPLPTFPTSECTSDVEPDTR 25 2 H0YHZ9;Q8TDD1;Q8TDD1-2 H0YHZ9 DDX54 ATP-dependent RNA helicase DDX54 1 KLGPGRPLPTFPTSECT(0.215)S(0.785)DVEPDTR;KLGPGRPLPTFPT(0.001)S(0.003)ECT(0.243)S(0.708)DVEPDT(0.044)R 83.944 3.6595e-06 45016000.0 37425.0 34322.0 60207.0 100802.0 79485.0 55777.0 47850.0 55671.0 43911.0 65752.0 True False 49325.37151164143 45415.915296708714 59408.61584144505 77563.65627537522 68449.87976097046 52289.25537260578 52108.55730226727 47068.32614231342 46232.045813916746 63450.04249335115 0.7773891013045447 0.7157743874082951 0.93630537517245 1.2224366324656601 1.0787995889544635 0.8241011876088988 0.8212533081869513 0.7418170940901363 0.7286369558974108 1.0 15.953333509808525 -6.966006272928177 23.571864441147863 0.8044494988673646 0.9484768271064238 0.1399515587769179 0.14959956654892959 199.66301462540423 138448.6212508058 0.05917879147244161 0.052190360767505516 1.0814183312318411e-07 6.966006272928177 0.14402732823905917 KLGPGRPLPTFPTSECTS(ph)DVEPDTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KLGPGRPLPTFPTSECTSDVEPDTR 25 2 H0YHZ9;Q8TDD1;Q8TDD1-2 H0YHZ9 DDX54 ATP-dependent RNA helicase DDX54 1 KLGPGRPLPTFPT(0.001)S(0.002)ECT(0.245)S(0.677)DVEPDT(0.074)R;KLGPGRPLPTFPT(0.004)S(0.004)ECT(0.377)S(0.587)DVEPDT(0.027)R 52.053999999999995 0.0053058 18216200.0 65385.0 48760.0 71435.0 106301.0 93578.0 98469.0 74912.0 106626.0 91173.0 63564.0 True False 76453.3890873843 53600.57055638629 73138.28131874625 100345.29960249204 75242.06265529357 93305.11229523242 67815.79304408682 103827.18047958547 92506.2326426301 75087.65002765278 1.0181885977151843 0.713840032770324 0.9740387572631634 1.3363755499810894 1.0020564317512124 1.2426159596267914 0.9031550863439204 1.3827464362161912 1.2319766647186656 1.0 16.196288020857338 -5.5388091056356705 13.337099775047113 1.1591704321033487 0.8604851927295999 0.3606919497160068 0.1598721139161227 0.9981743356648176 834.0283471560144 0.04128716962844409 0.07200362764512533 2.891950761491433e-06 5.5388091056356705 -0.2986852393737488 KLGPGRPLPTFPTSECTS(ph)DVEPDTR ddPTM_PC-9_Lapatinib_30min_R1 2 KLGPGRPLPTFPTSECTSDVEPDTR 25 2 H0YHZ9;Q8TDD1;Q8TDD1-2 H0YHZ9 DDX54 ATP-dependent RNA helicase DDX54 1 KLGPGRPLPT(0.001)FPT(0.026)S(0.028)ECT(0.196)S(0.743)DVEPDT(0.006)R;KLGPGRPLPT(0.004)FPT(0.014)S(0.011)ECT(0.251)S(0.712)DVEPDT(0.008)R 54.622 0.0021466 28972000.0 57151.0 38715.0 59649.0 46857.0 48438.0 40760.0 33236.0 36315.0 50710.0 35397.0 True False 56336.016259790194 38625.357796142525 54744.88947179858 50303.0200903698 45588.97207277203 39016.78981620075 34956.79745500305 38002.32747442537 44998.5058000267 41515.324286462266 1.3569932844812393 0.930387958181935 1.3186670322999343 1.211673543563602 1.0981239543788928 0.939816573441141 0.8420215439916993 0.9153807209165304 1.0839011033499326 1.0 15.341356347123217 -6.602346522521821 3.225696953677929 0.9435031932613206 1.1910306788686416 0.4807988251171297 0.12110395975957418 0.21821939672305812 4.570459674365328 0.04131706933320232 0.041854309859292574 2.4983511378493386e-07 6.602346522521821 0.24752748560732096 KLIDLES(ph)PTPESQK ddPTM_PC-9_AZD4547_30min_R2 2 KLIDLESPTPESQK 14 1 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 KLIDLES(0.985)PT(0.015)PESQK;KLIDLES(0.637)PT(0.357)PES(0.006)QK 62.361999999999995 0.022259 13943200.0 87491.0 70221.0 114232.0 160851.0 121088.0 128615.0 98921.0 134251.0 95940.0 108459.0 True False 115311.31807414869 92918.56500350167 112717.20904213702 123769.2870731769 104277.02133102331 120572.68371815768 107724.77736463054 113505.59273107583 101011.19253460807 104661.88342235019 1.101750840932453 0.8877975626383504 1.076965227037627 1.1825631550477755 0.9963228056027444 1.1520209628905818 1.0292646553083744 1.0844978995174197 0.9651191936513295 1.0 16.6753766004707 -10.48206969267466 8.64867598115276 1.000005123854848 1.0540688200393393 0.034920254861548816 0.08326895083764146 0.0 1.362720316742343e-10 0.07909267025126072 0.019182789929337717 3.2955682285847186e-11 10.48206969267466 0.05406369618449136 KLIDLES(ph)PTPESQK ddPTM_PC-9_Lapatinib_30min_R1 2 KLIDLESPTPESQK 14 1 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 KLIDLES(0.905)PT(0.095)PESQK;KLIDLES(0.684)PT(0.316)PESQK 136.81 2.8113000000000003e-05 10468500.0 147185.0 114780.0 121218.0 103870.0 133791.0 117478.0 111936.0 114889.0 128263.0 103987.0 True False 145086.11490957707 114514.23396206222 111251.92395501165 111508.94630016254 125921.67642322642 112453.73979459345 117731.49837294548 120227.16236291509 113816.67027073223 121961.01439603225 1.1896105950582938 0.9389413045566446 0.9121925109097075 0.9142999248765699 1.0324748203088332 0.9220466093323335 0.9653207539800164 0.9857835551655303 0.9332217416718618 1.0 16.896060529389068 -4.759131930937813 24.999234543272273 0.9545300463788835 1.1896109000508317 0.773176609080497 0.03794639457371228 28.150077124797857 304913.0200193899 0.009360272677664235 0.06095240389387525 1.741277823810974e-05 4.759131930937813 0.2350808536719482 KLLDFCK ddPTM_PC-9_AZD4547_30min_R2 1 KLLDFCK 7 1 B4DK69;P52895;H0Y804;Q04828 B4DK69;Q04828 AKR1C2;AKR1C1 Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 69.598 0.029197000000000004 5822700.0 37746.0 27132.0 44085.0 61855.0 52971.0 43388.0 44256.0 61442.0 39400.0 49669.0 False True 49748.44283442662 35901.88840482203 43500.40409537273 47595.285400223554 45616.890996016424 40674.94150109579 48194.69826476783 51947.55069670061 41482.60356330579 47930.10342806702 1.0379373144706132 0.7490467542742358 0.9075800172360918 0.99301445221486 0.9517377959444164 0.8486303719778177 1.0055204311648922 1.0838188733446597 0.865481202759398 1.0 15.548644432692187 -7.288919256320381 24.00694399063921 0.9956900569687228 0.9120554084622267 0.1399402767351131 0.08912134967674579 846.8896075822441 739854.2602271679 0.03680579068061869 0.024822934115112223 5.141392310480712e-08 7.288919256320381 -0.08363464850649616 KLLDS(ph)WFT(ph)S(ph)T(ph)QEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLLDSWFTSTQEK 13 1 Q8N5M9 Q8N5M9 JAGN1 Protein jagunal homolog 1 4 KLLDS(1)WFT(1)S(1)T(1)QEK 46.318000000000005 0.04483 1798200.0 498.29 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 582.640655323892 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KLLEGEEER ddPTM_PC-9_AZD4547_30min_R2 2 KLLEGEEER 9 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8;P20700;E9PBF6;Q03252 P02545;P02545-2;P20700;Q03252 LMNA;LMNB1;LMNB2 Prelamin-A/C;Lamin-A/C;Lamin-B1;Lamin-B2 0 ; 64.82 0.033411 9457200.0 41354.0 44332.0 52041.0 72169.0 66897.0 56030.0 42261.0 63399.0 45608.0 57555.0 False True 54503.711783364575 58661.45204048983 51350.90233701464 55531.55204993504 57609.50627627404 52526.435242610794 46022.14712959493 53602.141314086824 48018.74576942261 55540.01696837855 0.9813412879293143 1.0562015505664764 0.9245748406279932 0.9998475888394429 1.0372612293055967 0.9457403528075348 0.8286304117587401 0.9651084792538857 0.8645792419682166 1.0 15.761239997473076 -6.987816691209856 11.980352555281225 0.9081747156019822 0.9980867201262069 0.34707138891122025 0.055227451048450386 0.5335097526358242 517.3384934678885 0.01857385975106205 0.01621067028841478 1.0284502990337016e-07 6.987816691209856 0.08991200452422476 KLLEGEEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLLEGEEER 9 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8;P20700;E9PBF6;Q03252 P02545;P02545-2;P20700;Q03252 LMNA;LMNB1;LMNB2 Prelamin-A/C;Lamin-A/C;Lamin-B1;Lamin-B2 0 63.32 0.036689 3968000.0 30923.0 26378.0 30131.0 33903.0 40083.0 38886.0 28011.0 29556.0 28772.0 22020.0 False True 36157.6531429102 28996.633513871166 30849.437312453847 32003.524825008994 32229.023888223077 36846.749705109345 25357.595297921773 28780.186317170574 29192.73606872376 26012.051689775904 1.3900346490977507 1.114738424315386 1.18596709249887 1.2303345082767174 1.2390035308476173 1.4165260835458067 0.9748402625191089 1.1064173891551465 1.1222773357857823 1.0 14.666892575290529 -7.277380045002632 24.99480962553022 1.0597518636731547 1.2499934820830825 0.5499595988326338 0.09333413173125758 723.5423353907853 1134503.0239313266 0.03926647251159544 0.02657081363669548 5.27983019032113e-08 7.277380045002632 0.19024161840992782 KLLEGEEER ddPTM_PC-9_Lapatinib_30min_R1 1 KLLEGEEER 9 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8;P20700;E9PBF6;Q03252 P02545;P02545-2;P20700;Q03252 LMNA;LMNB1;LMNB2 Prelamin-A/C;Lamin-A/C;Lamin-B1;Lamin-B2 0 68.626 0.026926 3796600.0 49303.0 38959.0 39299.0 34010.0 40164.0 36652.0 31376.0 31401.0 34836.0 31056.0 False True 48599.930178937146 38868.79282913382 36067.98791852695 36511.20885403414 37801.632485462185 35084.47939998504 33000.49575605295 32860.00509498639 30912.40284065727 36423.988220481166 1.3342836013660213 1.0671207280722197 0.9902262130165627 1.0023945931737352 1.0378224442815511 0.9632245427824149 0.906009950263953 0.9021528586073188 0.8486825400211189 1.0 15.152601277451657 -1.5228787452806043 0.6822199307674146 0.9346948432637766 43.572220099620836 0.837196068515408 0.051065055740091174 106.03259710495084 0.6041126762939555 0.02229268492602436 6873.92879651141 0.029999999999981576 1.5228787452806043 42.63752525635706 KLLLDPSS(ph)PPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLLLDPSSPPTK 12 1 F5GX19;F5H3Y3;Q6IAA8;H0YFI1;F5H479 F5GX19 LAMTOR1 Ragulator complex protein LAMTOR1 1 KLLLDPS(0.245)S(0.661)PPT(0.094)K 55.782 0.036345 12219000.0 59242.0 53193.0 52076.0 55277.0 76734.0 57508.0 57357.0 59949.0 52612.0 41587.0 True False 69270.50051716475 58473.64949970991 53317.689339329816 52180.008900451954 61698.52353962805 54492.17924295193 51923.72973128058 58375.40227121597 53381.350967874845 49126.39389748916 1.4100465151525228 1.1902695243971182 1.0853165703671743 1.062158338129493 1.2559139526579712 1.1092240834256921 1.05694160738988 1.1882696375603405 1.0866124446110252 1.0 15.584210722095564 -4.789155920722796 2.809193116884186 1.1149174782886562 1.4614151677396512 0.6429661392977308 0.06822331195523232 0.26414549969073453 2.9118141915297215 0.017147239827870687 0.2124845886998334 1.6249652547970323e-05 4.789155920722796 0.346497689450995 KLMQVNDT(ph)LT(ph)S(ph)EDAGLRNSK ddPTM_PC-9_Lapatinib_30min_R1 1 KLMQVNDTLTSEDAGLRNSK 20 2 Q9HC58 Q9HC58 SLC24A3 Sodium/potassium/calcium exchanger 3 3 KLMQVNDT(0.999)LT(0.845)S(0.845)EDAGLRNS(0.311)K 46.578 0.041802 0.0 10524.0 27982.0 35257.0 36231.0 32502.0 28415.0 22106.0 20895.0 33877.0 25332.0 True False 10373.92583013477 27917.209398208957 32358.305555955718 38895.548603072944 30590.2962613906 27199.756688600224 23250.540514511285 21865.857980947763 30061.415519374998 29710.60244723174 0.34916578512871427 0.9396379439895914 1.0891164396086042 1.3091470855279477 1.0296087504695086 0.9154899075812762 0.7825671174391697 0.7359614474254828 1.0118076727917695 1.0 14.858690238806306 -10.183113606201799 14.856613425620738 1.0002868025842522 0.9202657394466969 0.010578211522855097 0.2407399828470576 0.0 0.0 0.24498095726239932 0.05941660959163521 6.559736490574146e-11 10.183113606201799 -0.0800210631375553 KLNLTLS(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 1 KLNLTLSPAK 10 1 A0A087WTW5;Q9UKL3 A0A087WTW5 CASP8AP2 CASP8-associated protein 2 1 KLNLT(0.02)LS(0.98)PAK 53.376999999999995 0.045752 5488400.0 51671.0 40885.0 39474.0 39043.0 40590.0 40305.0 32298.0 33945.0 39108.0 32515.0 True False 50934.16206469911 40790.33329446693 36228.60009404645 41914.352463629955 38202.5760030104 38581.249105543975 33970.23240467228 35522.20862231498 34703.24521450297 38135.17442648585 1.3356215837660896 1.0696249304719845 0.950004835139413 1.0990995345892367 1.0017674385272441 1.01169719781715 0.8907847653917924 0.9314814775737306 0.910006201267056 1.0 15.218834678065612 -1.522878746071299 0.8977669708615729 0.9642812852651907 181.47052515603247 0.7851688337681868 0.05689300043719581 423.4149991237578 0.9441317914617593 0.020492883148530358 156566.23646819583 0.029999999945362326 1.522878746071299 180.50624387076726 KLNSSSSSSSNSS(ph)NEREDFDSTSSSSSTPPLQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPR 34 2 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 KLNSSSS(0.001)S(0.001)S(0.007)S(0.007)NS(0.048)S(0.436)NEREDFDS(0.021)T(0.01)S(0.019)S(0.069)S(0.095)S(0.095)S(0.095)T(0.095)PPLQPR 53.995 0.00041597 12615000.0 11707.0 8045.4 12985.0 14709.0 15199.0 13969.0 15780.0 13643.0 12504.0 10903.0 True False 13688.763876210245 8844.094141803738 13294.61164588673 13884.902417221407 12220.86505693442 13236.441048980929 14285.20416269344 13284.885705953386 12686.847344756072 12879.627591899494 1.0628229565286227 0.6866731261209864 1.032220190453972 1.0780515444370589 0.9488523615869612 1.0277037091744678 1.109131771145151 1.031465049060019 0.9850321567321815 1.0 13.652803258787136 -5.406418026816419 19.051845131652886 1.0298001074380934 0.8708641999060803 0.29259441292903055 0.0942653380991821 3.7106303542465415 596.2032405066693 0.02287583123850328 0.04761997873343673 3.922671798661397e-06 5.406418026816419 -0.15893590753201303 KLNSSSSSSSNSS(ph)NEREDFDSTSSSSSTPPLQPR ddPTM_PC-9_Lapatinib_30min_R1 1 KLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPR 34 2 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 KLNSSSSS(0.001)S(0.002)S(0.002)NS(0.111)S(0.45)NEREDFDS(0.054)T(0.054)S(0.054)S(0.054)S(0.054)S(0.054)S(0.054)T(0.054)PPLQPR 60.527 0.00013076 20316000.0 48016.0 38560.0 50947.0 40840.0 46600.0 45004.0 32736.0 36162.0 48501.0 31702.0 True False 47331.28303494403 38470.716689119356 46758.33432110719 43843.509838246195 43859.07961912501 43079.283829447966 34430.90990152184 37842.218535871434 43038.30664182796 37181.64845974027 1.2729743030676446 1.0346694749366714 1.257564854117117 1.1791706837774902 1.179589432851934 1.1586168342184604 0.9260189186825084 1.0177660244635582 1.1575147532371837 1.0 15.182303113550038 -7.114339735602861 7.1904520244907015 1.0272182586802685 1.1790835821063497 0.4761569855766876 0.07994683920931193 0.23866610920444747 13.486776914004254 0.02982413730201895 0.02309237322419935 7.685290077854922e-08 7.114339735602861 0.15186532342608117 KLNSSSSSSSNSSNEREDFDSTS(ph)SSSSTPPLQPR ddPTM_PC-9_AZD4547_30min_R2 1 KLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPR 34 2 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 KLNSSSSSS(0.001)SNS(0.001)S(0.004)NEREDFDS(0.107)T(0.107)S(0.13)S(0.13)S(0.13)S(0.13)S(0.13)T(0.13)PPLQPR 45.983000000000004 0.0037059 23032000.0 20651.0 17571.0 32628.0 54041.0 39064.0 36782.0 25784.0 34954.0 28820.0 30130.0 True False 27217.588432515902 23250.48213036738 32195.331401243522 41582.68237512702 33640.637893722735 34482.0157253919 28078.726049773435 29552.662463013483 30343.366362803892 29075.157870858257 0.936111458221722 0.7996683021855957 1.1073140701159385 1.4301790745151872 1.1570233958193024 1.1859614272276364 0.9657291002335868 1.0164231126199257 1.043618283951495 1.0 14.827499404743591 -5.277773496215082 18.33432925614437 1.1240743368282426 0.8678903974294017 0.36397138782551486 0.12912577640060124 24.302720985026877 27280.658426943217 0.03682028386150114 0.07759950985083404 5.275049068374377e-06 5.277773496215082 -0.256183939398841 KLNSSSSSSSNSSNEREDFDSTSSSSS(ph)TPPLQPR ddPTM_PC-9_Lapatinib_30min_R1 2 KLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPR 34 2 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 KLNSSSSSS(0.001)SNS(0.002)S(0.002)NEREDFDS(0.035)T(0.035)S(0.095)S(0.095)S(0.095)S(0.095)S(0.273)T(0.273)PPLQPR;KLNSSSSSS(0.001)S(0.001)NS(0.001)S(0.001)NEREDFDS(0.004)T(0.004)S(0.009)S(0.045)S(0.122)S(0.122)S(0.346)T(0.346)PPLQPR 47.376000000000005 0.0031336 30402000.0 51221.0 35090.0 46099.0 39711.0 46576.0 41600.0 27690.0 31305.5 48187.0 30963.7 True False 50490.579147219025 35008.75126092318 42308.91816728602 42631.4794120126 43836.49125193918 39820.86497433638 29123.652711789462 32760.067816346505 42759.67262839458 36315.73428846317 1.3903224080824639 0.9640105575958243 1.1650299517894307 1.1739120865182622 1.207093622387947 1.0965182380185747 0.8019568730306935 0.9020901947383662 1.1774420500146277 1.0 15.14830713057302 -7.014181679810284 20.863026721072206 0.9603593264721505 1.1653836794100134 0.36148721047050136 0.13043928288610768 83.0938571286035 122241.25689343418 0.04752813123849504 0.038452494136316795 9.67872878178816e-08 7.014181679810284 0.20502435293786292 KLNSSSSSSSNSSNEREDFDSTSSSSST(ph)PPLQPR ddPTM_PC-9_AZD4547_30min_R2 1 KLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPR 34 2 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 KLNSSSSSSSNSSNEREDFDS(0.002)T(0.002)S(0.006)S(0.021)S(0.038)S(0.115)S(0.362)T(0.452)PPLQPR 54.153 0.0005182 22376000.0 33481.0 30162.0 42277.0 52888.0 56290.0 51575.0 39013.0 50595.0 39071.0 41187.0 True False 44127.26155193766 39911.27664994255 41716.379356698926 40695.4887114546 48475.10513612664 48350.007096870446 42485.08142180468 42776.70530743741 41136.21329497263 39745.055666347114 1.1102578877327136 1.0041821801682913 1.0495992182499563 1.0239132397520387 1.2196512075128738 1.2165036955227944 1.0689400407049272 1.0762774033213207 1.0350020299456628 1.0 15.278487778076999 -4.365943874224002 20.535350345963856 1.0838685869701155 45.18359883349212 0.010070604974685038 0.07539914895251845 3400.6412993370022 446147.8337764501 0.019692195845345154 18535.74479381983 4.3058225292458104e-05 4.365943874224002 44.09973024652201 KLNSSSSSSSNSSNEREDFDSTSSSSST(ph)PPLQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPR 34 2 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 KLNSSSSSSSNSSNEREDFDS(0.01)T(0.008)S(0.022)S(0.067)S(0.212)S(0.212)S(0.212)T(0.257)PPLQPR 56.653999999999996 0.00038614 19761000.0 42579.0 30512.0 46454.0 57010.0 59564.0 52343.0 53021.0 46568.0 54197.0 42727.0 True False 49786.78372641635 33541.02971321693 47561.63953777604 53815.91452891376 47892.86178375168 49598.04093541475 47998.467041202064 45345.63934287451 54989.52859434943 50473.0668732541 0.986402983029323 0.6645332212017905 0.9423172096360002 1.0662303256517793 0.9488795658884425 0.9826635076478177 0.9509718749949126 0.8984126020466444 1.0894826092584562 1.0 15.623226130707447 -5.504297710970201 24.838853530373896 0.984592180321929 0.819957351734729 0.3474302427709569 0.08921959064274995 668.5803806313138 893746.8753061384 0.021781053277123 0.04408633294675075 3.131138577803926e-06 5.504297710970201 -0.16463482858720002 KLNVTEQEK ddPTM_PC-9_AZD4547_30min_R2 1 KLNVTEQEK 9 1 P06733;K7EM90;A0A2R8YEM5;A0A2R8Y879;A0A2R8Y6I8 P06733 ENO1 Alpha-enolase;Enolase 0 89.561 0.0058537 22036000.0 121090.0 136000.0 132150.0 186840.0 158020.0 174530.0 144570.0 161830.0 138490.0 124640.0 False True 159594.10117153425 179959.34037504788 130397.60465472401 143766.92464922453 136081.65062374747 163616.61150977763 157436.44993080024 136822.89198344917 145810.29866706146 120276.39153746332 1.3268946559793022 1.4962149934386308 1.084149623944348 1.195304604764805 1.1314078256277016 1.360338545397871 1.308955547454734 1.1375706423719238 1.2122935914787976 1.0 16.875993965210796 -14.522878745279929 0.07836604585771445 0.21689642931611552 1.4943434242344051 0.3459652860694883 0.11357166482506315 335.12493342905185 1.8578870496127198 46.18451906766126 4.492804570312997 3.0000000000028236e-15 14.522878745279929 1.2774469949182896 KLNVTEQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KLNVTEQEK 9 1 P06733;K7EM90;A0A2R8YEM5;A0A2R8Y879;A0A2R8Y6I8 P06733 ENO1 Alpha-enolase;Enolase 0 ; 89.561 0.0058537 60124000.0 147878.0 170965.0 151021.0 157250.0 168808.0 118235.0 154671.0 134614.0 127122.0 123642.0 False True 172910.8246763665 187937.27533167755 154621.9133903316 148439.79231137884 135731.28419836768 112034.54845917824 140019.44315893287 131080.5251353225 128980.9187588039 146057.31585046675 1.1838559655128287 1.2867364721674568 1.0586386069742189 1.0163119282799313 0.9293015102189688 0.7670587933703987 0.9586609362470043 0.8974594964453717 0.8830842741958531 1.0 17.15617509742315 -5.665746125937298 1.4876403177604862 0.8977037289575368 1.2427339881842885 0.779946108939876 0.06713892556639808 0.17973042676530893 0.7858021486518998 0.021175643076213117 0.055359008766293925 2.1590061232772935e-06 5.665746125937298 0.3450302592267517 KLNVTEQEK ddPTM_PC-9_Lapatinib_30min_R1 2 KLNVTEQEK 9 1 P06733;K7EM90;A0A2R8YEM5;A0A2R8Y879;A0A2R8Y6I8 P06733 ENO1 Alpha-enolase;Enolase 0 ; 83.045 0.0094222 112559000.0 384760.0 337470.0 350580.0 287930.0 294170.0 262869.0 344210.0 294120.0 288508.0 312060.0 False True 379273.2518436573 336688.6089490944 321756.66567793454 309105.3327063224 276867.49896047235 251626.7056475682 362031.50956753513 307785.8889378496 256013.1909160738 365999.1552061872 1.0362681073129583 0.9199163554337152 0.879118602054345 0.8445520387395063 0.7564703224642632 0.6875062471273006 0.9891594131237355 0.8409469927996339 0.6994912072183546 1.0 18.481480792942712 -4.820326558529707 1.2179078123421563 0.8230915098452086 1.120121629545282 0.2852861664361692 0.09926244723761608 1.7914083409563037 2.3812400016299127 0.030317294585048105 0.6652669020922611 1.5124235859133844e-05 4.820326558529707 0.2970301197000734 KLPPPPGS(ph)PLGHSPTASPPPTAR ddPTM_PC-9_AZD4547_30min_R2 2 KLPPPPGSPLGHSPTASPPPTAR 23 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785;O95785-2 B9EGQ5 WIZ Protein Wiz 1 KLPPPPGS(0.999)PLGHS(0.001)PTASPPPTAR;KLPPPPGS(0.867)PLGHS(0.128)PT(0.005)AS(0.001)PPPTAR 104.54 9.7787e-07 55751000.0 128621.0 148128.0 207750.0 258964.0 223707.0 185840.0 155995.0 228396.0 170315.0 185972.0 True False 169519.80251700248 196007.47919908148 204995.09925856147 199263.85075391654 192649.14451390054 174219.3954218592 169878.25279764232 193102.64621795595 179317.50319503644 179461.17688547092 0.9446043175409863 1.0921998986118882 1.1422810371369951 1.110345168866709 1.0734864657487784 0.9707915575135398 0.9466016870381706 1.0760134841932458 0.9991994163142808 1.0 17.453312251784737 -6.7072279960530325 8.310482242429227 1.0000957781273425 1.0799323273974701 0.29064492875125325 0.057267611627192544 0.3520996388291182 48.46738189974792 0.01980507366409588 0.019731047300725984 1.9623298218513887e-07 6.7072279960530325 0.07983654927012762 KLPPPPGS(ph)PLGHSPTASPPPTAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLPPPPGSPLGHSPTASPPPTAR 23 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785;O95785-2 B9EGQ5 WIZ Protein Wiz 1 KLPPPPGS(0.998)PLGHS(0.002)PTASPPPTAR 84.03 1.3669e-05 12277000.0 26575.0 26649.0 32151.0 32408.0 35112.0 39759.0 37732.0 38492.0 45606.0 34120.0 True False 31073.62261982466 29294.536602894535 32917.60177334649 30592.284828153603 28232.05565360099 37673.96804828065 34157.751803976484 37481.625785645214 46272.90147192461 40305.68590622861 0.7709488604689076 0.7268090331237242 0.8166987121849126 0.7590066795867638 0.7004484607775443 0.9347060396374183 0.8474673246708833 0.9299339520693536 1.1480489769998894 1.0 15.29869575304445 -7.605083217586717 1.0208662354919948 1.064684343552937 0.7618539115064934 0.7359565910686395 0.06822552537728406 0.27233445067359735 0.5191946983375749 0.05602642715710236 0.02478103747525245 2.4826573439017693e-08 7.605083217586717 -0.30283043204644355 KLPPPPGS(ph)PLGHSPTASPPPTAR ddPTM_PC-9_Lapatinib_30min_R1 1 KLPPPPGSPLGHSPTASPPPTAR 23 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785;O95785-2 B9EGQ5 WIZ Protein Wiz 1 KLPPPPGS(0.991)PLGHS(0.008)PT(0.001)ASPPPTAR 76.237 0.00013029 13845000.0 77950.0 65927.0 89311.0 74648.0 85213.0 81534.0 89482.0 98083.0 107860.0 93540.0 True False 76838.41870572069 65774.35008204277 81968.19433042992 80137.86293842824 80200.93887520391 78046.98088503706 94114.94012121148 102640.2942495955 95711.670983847 109708.26436578449 0.7003886092804221 0.5995386989510728 0.7471469428878681 0.730463319255841 0.7310382616919492 0.7114047545663127 0.8578655460942993 0.9355748615927122 0.8724198813749284 1.0 16.743312683044294 -7.508610109473076 0.6205431737611717 0.9911699029523949 0.6702674372293401 0.8392214755303101 0.046762886079745186 0.2917836816629687 0.2256687851102819 0.04426924592219305 0.027469735067664647 3.100201274914774e-08 7.508610109473076 -0.3209024657230548 KLQLERPVS(ph)PETQADLQR ddPTM_PC-9_Lapatinib_30min_R1 1 KLQLERPVSPETQADLQR 18 2 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 KLQLERPVS(0.87)PET(0.13)QADLQR 41.348 0.04338 14066000.0 81127.0 57886.0 62602.0 45829.0 54223.0 54906.0 42941.0 39381.0 60923.0 46948.0 True False 79970.1141031302 57751.96852350527 57455.105210708265 49199.417541062336 51033.709746519635 52557.79837213733 45164.27486807331 41210.78502740869 54061.210192368926 55062.899245722205 1.452341144374867 1.048836318367162 1.0434449692579875 0.8935130226526276 0.926825692900368 0.9545047407982337 0.8202305996733743 0.7484310777662206 0.981808276224556 1.0 15.748792954199715 -1.5228787452803645 0.7799189956545579 0.887417788679618 121.94501133010495 0.8105399260402362 0.07809332604319144 176.53658530358248 0.6700058765000052 0.028168981570916386 37680.94415060332 0.02999999999999814 1.5228787452803645 121.05759354142533 KLS(ph)EADNR ddPTM_PC-9_Lapatinib_30min_R1 1 KLSEADNR 8 1 C9J365;C9JA28;Q9UNL2;Q9UNL2-2 C9J365 SSR3 Translocon-associated protein subunit gamma 1 KLS(1)EADNR 90.65299999999999 0.010459 0.0 40596.0 36563.0 18674.0 14088.0 20652.0 18611.0 20109.0 16699.0 25036.0 10793.0 True False 40017.09359560538 36478.34061992403 17138.695803724564 15124.078516190315 19437.28996339421 17815.050914359977 21150.14562590734 17474.89650269667 22216.182039232295 12658.555669231491 3.1612685239338085 2.8817142787142833 1.3539219048017241 1.1947712607490952 1.5355061407708184 1.4073525748014142 1.6708182338144568 1.3804810721946748 1.7550329294859477 1.0 13.627825183390863 -5.22407587737558 4.908947311285403 1.4290093725402364 3.0701710291313775 0.9027636875391302 0.2115797513590264 0.051340469368217734 3.1313484556445403 0.052772262235085764 0.14239675360059945 5.9693098520449736e-06 5.22407587737558 1.641161656591141 KLS(ph)FLSWGTNK ddPTM_PC-9_AZD4547_30min_R2 1 KLSFLSWGTNK 11 1 Q8IUC4-2;A8MT19;Q8IUC4 Q8IUC4-2 RHPN2;RHPN2P1 Rhophilin-2;Putative rhophilin-2-like protein RHPN2P1 1 KLS(0.943)FLS(0.046)WGT(0.01)NK 53.038000000000004 0.044212 5442300.0 24259.0 25434.0 35838.0 40381.0 34133.0 29217.0 28314.0 35834.0 30056.0 29512.0 True False 31972.857381453807 33655.0431110218 35362.764703866764 31071.784330230847 29394.222128467056 27390.056371289655 30833.891148514016 30296.678683401773 31644.69879945987 28478.793862753704 1.1226900105228772 1.181758022239766 1.2417226963434127 1.0910498695967743 1.0321442077261076 0.961770238700735 1.0826965248988458 1.0638329287893618 1.111167100403319 1.0 14.797600425956585 -5.95057503500638 5.5070479475434855 1.0444934077125743 1.181408912545868 0.6359343564349311 0.047346126500117394 0.12784092136577865 8.699777955970434 0.01412329681747894 0.021013065412126754 1.1205338097568371e-06 5.95057503500638 0.13691550483329373 KLS(ph)FLSWGTNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KLSFLSWGTNK 11 1 Q8IUC4-2;A8MT19;Q8IUC4 Q8IUC4-2 RHPN2;RHPN2P1 Rhophilin-2;Putative rhophilin-2-like protein RHPN2P1 1 KLS(0.972)FLS(0.028)WGTNK;KLS(0.827)FLS(0.16)WGT(0.014)NK 88.78 0.0044198 13877700.0 77140.0 69730.0 65879.0 69146.0 73448.0 67115.0 59935.0 50602.0 59667.0 55111.0 True False 90198.27841555123 76652.3335704842 67449.80520749874 65271.973794356716 59056.39165087963 63595.37125079492 54257.52290817686 49273.75111725081 60539.51699612614 65102.18804156403 1.3854876637627722 1.1774156272834648 1.036060495607857 1.0026079884240493 0.9071337450774388 0.9768545906658759 0.833420880931629 0.7568678196467425 0.9299152427484483 1.0 15.990418411783159 -3.8470943160629236 0.5589604812172029 0.8724220010189636 2.595472673495866 0.8421165844289058 0.06676284310155722 3.6572636168406767 0.3956056204863537 0.03422436373772329 5.153608562060003 0.00014220199324367313 3.8470943160629236 1.7230506724769026 KLS(ph)FLSWGTNK ddPTM_PC-9_Lapatinib_30min_R1 2 KLSFLSWGTNK 11 1 Q8IUC4-2;A8MT19;Q8IUC4 Q8IUC4-2 RHPN2;RHPN2P1 Rhophilin-2;Putative rhophilin-2-like protein RHPN2P1 1 KLS(0.962)FLS(0.037)WGT(0.001)NK;KLS(0.813)FLS(0.167)WGT(0.02)NK 66.059 0.019778999999999998 6986200.0 56174.0 49449.0 55059.0 44629.0 48537.0 45035.0 44695.0 49593.0 47676.0 46266.0 True False 55372.94845895003 49334.50387863751 50532.26155388623 47911.165537979665 45682.149087413534 43108.95803171252 47009.088405685434 51897.27182814751 42306.226829463085 54263.01645443008 1.0204546683366205 0.9091736343125797 0.9312468206835327 0.8829432764434562 0.8418652716399809 0.7944445563197781 0.8663191152516102 0.9564022647309091 0.7796512172335964 1.0 15.727681628107069 -3.790901636033923 0.858433554904327 0.8695098427556699 1.63937525985112 0.29824678270186766 0.06442790229084823 12.732424387416476 2.03717610893448 0.021599728182772764 13.80180647471379 0.00016184465603648573 3.790901636033923 0.7698654170954501 KLS(ph)FTESLTSGASLLTLNK ddPTM_PC-9_AZD4547_30min_R2 1 KLSFTESLTSGASLLTLNK 19 1 P19838;P19838-2;P19838-3 P19838 NFKB1 Nuclear factor NF-kappa-B p105 subunit;Nuclear factor NF-kappa-B p50 subunit 1 KLS(0.439)FT(0.439)ES(0.116)LT(0.005)S(0.002)GASLLTLNK 75.226 0.0018812999999999998 1152700.0 7153.1 4375.7 8384.9 8541.1 7973.5 7055.6 6558.0 7209.2 8198.9 4541.2 True False 9427.637006277146 5790.059453522765 8273.710747403664 6572.081353679567 6866.51715762846 6614.412216629745 7141.649295470614 6095.18379093542 8632.277115613904 4382.213970233704 2.151341096147884 1.3212635195022164 1.8880207136399656 1.49971712890347 1.5669059530797553 1.5093768267725636 1.6296897741599208 1.3908914152383034 1.969843821924 1.0 12.097444213138704 -11.565892659894036 2.8039532310300452 0.161798365126068 1.6349122374210725 0.37595596581982726 0.25289375276557247 16258131.836257508 27927272.409327514 90218275.96872303 0.057560855572636044 2.7171107462072153e-12 11.565892659894036 1.4731138722950046 KLS(ph)FTESLTSGASLLTLNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLSFTESLTSGASLLTLNK 19 1 P19838;P19838-2;P19838-3 P19838 NFKB1 Nuclear factor NF-kappa-B p105 subunit;Nuclear factor NF-kappa-B p50 subunit 1 KLS(0.41)FT(0.41)ES(0.178)LT(0.002)SGASLLTLNK 81.839 0.010761 0.0 7845.9 8258.2 8298.8 7631.3 10071.0 8842.2 7140.1 6349.6 7849.6 5263.2 True False 9174.055906411375 9078.019519457528 8496.67486537426 7203.743002008413 8097.659845278415 8378.499466196523 6463.738038152557 6182.929727957311 7964.385550015779 6217.376496531724 1.4755509677641354 1.4601045190880066 1.3666013100725056 1.1586467388659702 1.3024239162282645 1.3475940327677358 1.0396246779905098 0.9944595974534229 1.2809881393637008 1.0 12.602090229346185 -1.522878753921566 0.18062456920098668 0.9820748993943756 3.2879852891422443 0.6304128193687581 0.1055961134800007 37.023595907936084 0.4181787814546149 0.2473898683124391 23.45088786711025 0.029999999403085092 1.522878753921566 2.3059103897478685 KLS(ph)GDQITLPTTVDYSSVPK ddPTM_PC-9_AZD4547_30min_R2 2 KLSGDQITLPTTVDYSSVPK 20 1 E9PJ38;E9PND3;E9PN10;O00559;O00559-2 E9PJ38 EBAG9 Receptor-binding cancer antigen expressed on SiSo cells 1 KLS(1)GDQITLPTTVDYSSVPK;KLS(1)GDQITLPTTVDYSSVPK 121.5 4.5479e-06 361080000.0 801730.0 835650.0 993040.0 1201250.0 1033390.0 771980.0 999650.0 1019600.0 941760.0 846140.0 True False 1056663.462980048 1105757.5204735922 979871.6407591896 924320.3716274932 889921.6361098231 723707.9685631045 1088616.913421345 862044.2480771443 991539.5109588542 816516.8961449732 1.2941109583511137 1.3542371574846923 1.2000629079269078 1.1320284687206024 1.0898998420135777 0.886335570004677 1.3332448092146523 1.0557580034744163 1.2143527165698793 1.0 19.639123214151958 -5.530053023299025 2.3521081690755428 1.1025966288766615 1.3257308240912802 0.3801876458848843 0.11331992235032443 0.314027727376195 3.4390470711684813 0.031941497373023375 0.07519288935964107 2.9508489335849132e-06 5.530053023299025 0.22313419521461864 KLS(ph)GDQITLPTTVDYSSVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KLSGDQITLPTTVDYSSVPK 20 1 E9PJ38;E9PND3;E9PN10;O00559;O00559-2 E9PJ38 EBAG9 Receptor-binding cancer antigen expressed on SiSo cells 1 KLS(1)GDQITLPTTVDYSSVPK;KLS(0.999)GDQIT(0.001)LPTTVDYSSVPK 116.92 7.8432e-06 255280000.0 351290.0 354530.0 293070.0 346200.0 385620.0 288760.0 333100.0 240990.0 310390.0 304200.0 True False 410756.45870623493 389725.39539285545 300057.900274165 326803.53639554296 310060.52919633227 273616.91726707254 301546.35656484123 234664.26785001086 314928.8665498105 359349.0519541244 1.1430570262327375 1.0845315808502787 0.8350040125122447 0.909432026099414 0.8628394245378879 0.7614237905433608 0.8391461030022073 0.6530259828818716 0.87638708057595 1.0 18.455026354338017 -5.035975531669817 1.1231194973712768 0.8154660719555753 1.2499164717490039 0.580833732780089 0.0899811252485806 0.7244324353369145 1.0246811100109916 0.027939444179596602 0.33612718301698424 9.205014317224648e-06 5.035975531669817 0.4344503997934286 KLS(ph)GDQITLPTTVDYSSVPK ddPTM_PC-9_Lapatinib_30min_R1 2 KLSGDQITLPTTVDYSSVPK 20 1 E9PJ38;E9PND3;E9PN10;O00559;O00559-2 E9PJ38 EBAG9 Receptor-binding cancer antigen expressed on SiSo cells 1 KLS(1)GDQITLPTTVDYSSVPK;KLS(0.998)GDQIT(0.002)LPTTVDYSSVPK 131.26 1.7934e-05 279300000.0 214001.0 185027.0 146872.0 117338.0 130983.0 136426.0 129320.0 126397.0 166195.0 73026.0 True False 210949.30649702295 184598.5813495249 134796.75110231552 125967.42794809355 123278.8374624861 130591.37800453875 136015.55683238027 132269.86605493425 147476.36898906413 85648.44679897137 2.462967098424445 2.155305650583519 1.573837660111945 1.470749705990073 1.4393587049142689 1.5247372589377435 1.588067990907382 1.5443346727044533 1.7218802500319865 1.0 16.386139463386577 -5.142613197445979 2.326773239218929 1.4958768110761964 2.4636687881542567 0.7835436443932975 0.17758083409031464 0.14428098357365246 1.3980631871497144 0.04553122706013187 0.2039153134645981 7.200900376467082e-06 5.142613197445979 0.9677919770780603 KLS(ph)GDQPAAR ddPTM_PC-9_AZD4547_30min_R2 4 KLSGDQPAAR 10 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 KLS(1)GDQPAAR;KLS(1)GDQPAAR;KLS(1)GDQPAAR;KLS(1)GDQPAAR 84.352 0.0057756 1680728600.0 467188.0 464220.0 596059.0 761079.0 655279.0 679553.0 535637.0 677576.0 536945.0 568298.0 True False 615744.0658859254 614270.0366831219 588154.8682019679 585623.9951033349 564304.8217888778 637060.4434842377 583307.6553336378 572872.1983475086 565326.8165050565 548402.0599964499 1.1227967777690542 1.120108915504618 1.0724884370525074 1.0678734414439035 1.0289983626110575 1.1616667586703846 1.0636496429962607 1.044620799475511 1.0308619491850854 1.0 19.06487446484841 -6.656308348231662 0.012989359218550267 6.44958238872672e-08 2.1542305396859365 0.4515932044696179 0.03512103709805909 1563.3485506610248 7.394141685949918 589.2282393321792 636.2910659446404 2.2064376103752796e-07 6.656308348231662 2.1542304751901127 KLS(ph)GDQPAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 KLSGDQPAAR 10 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 KLS(1)GDQPAAR;KLS(1)GDQPAAR;KLS(1)GDQPAAR;KLS(1)GDQPAAR;KLS(1)GDQPAAR;KLS(1)GDQPAAR 84.169 0.012909 1263075700.0 404253.0 413214.0 423457.0 456651.0 471749.0 413010.0 489341.0 441793.0 422504.0 335482.0 True False 472685.048539304 454235.15508381074 433553.820849616 431066.3249525169 379313.1699285328 391351.0285374477 442987.07795795635 430196.4018683773 428682.32170096214 396302.23092594923 1.1927388029961083 1.1461836942540111 1.0939979314187294 1.087721166608985 0.957131048801512 0.9875064988230493 1.11780112093472 1.0855260664650694 1.081705547554849 1.0 18.596241563208125 -5.304297324542719 1.4979657271280102 1.0452247582853726 1.1930148714318145 0.5298695064988168 0.047806422600905 0.4747365201107938 1.768475655366503 0.016001483214960328 0.07722399156924194 4.962524632177736e-06 5.304297324542719 0.14779011314644186 KLS(ph)GDQPAAR ddPTM_PC-9_Lapatinib_30min_R1 5 KLSGDQPAAR 10 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 KLS(1)GDQPAAR;KLS(1)GDQPAAR;KLS(1)GDQPAAR;KLS(1)GDQPAAR;KLS(1)GDQPAAR 65.809 0.021932 1821924000.0 682571.0 651152.0 725291.0 634629.0 754569.0 694555.0 681299.0 675321.0 755916.0 555728.0 True False 672837.412371808 649644.2975506586 665660.3736842246 681301.7337202841 710186.7349597334 664850.5017367849 716573.3285983909 706698.8790405197 670776.7799316308 651784.8443389854 1.0322998735175766 0.9967158690372777 1.0212885117930461 1.0452862468921529 1.0896030202727052 1.0200459668727804 1.099401642769266 1.0842517821309976 1.0291383510334706 1.0 19.31403628056178 -5.810012331304378 3.4185604510502126 1.059110098717066 1.0137352868221614 0.20664160743232485 0.031291241125975304 0.295693254578542 7.050024417238979 0.00869680036173864 0.014324354694909988 1.5487726426272516e-06 5.810012331304378 -0.045374811894904665 KLS(ph)LGQYDNDAGGQLPFSK ddPTM_PC-9_AZD4547_30min_R2 1 KLSLGQYDNDAGGQLPFSK 19 1 Q68CZ2;Q68CZ2-2;E9PCX8 Q68CZ2 TNS3 Tensin-3 1 KLS(0.825)LGQY(0.174)DNDAGGQLPFSK 49.865 0.028811 83502000.0 22982.0 27786.0 24804.0 42266.0 36758.0 30861.0 22793.0 31507.0 29242.0 34775.0 True False 30289.797944703903 36767.28111515496 24475.082753354305 32522.22670319051 31654.7861892653 28931.25679140125 24821.53284410822 26638.317108833468 30787.67242127381 33557.53783468623 0.9026227756613099 1.095648950655463 0.7293467975488958 0.969148179565618 0.9432988303613212 0.8621388414705714 0.7396708592384221 0.7938102384048923 0.9174592180434231 1.0 15.03434924657873 -6.86374903711824 5.261340123346909 0.8399306417932579 0.9283137912184272 0.06933402560930169 0.10680202065245525 0.44557523243976116 19.199606665727377 0.03749485367932077 0.033134676363451715 1.3685194144163714e-07 6.86374903711824 0.08838314942516923 KLS(ph)LGQYDNDAGGQLPFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KLSLGQYDNDAGGQLPFSK 19 1 Q68CZ2;Q68CZ2-2;E9PCX8 Q68CZ2 TNS3 Tensin-3 1 KLS(0.893)LGQY(0.107)DNDAGGQLPFSK;KLS(0.977)LGQY(0.023)DNDAGGQLPFSK 75.896 0.0017855 116735000.0 494790.0 455000.0 388152.0 451120.0 537520.0 552480.0 467540.0 564850.0 484340.0 413426.0 True False 578548.1744520436 500169.3930097582 397407.01575465675 425845.20895077265 432196.8146196052 523506.9762145449 423251.22650352947 550023.2860080468 491422.55621874245 488376.8611215848 1.1846346960897685 1.0241463771667871 0.8137302304658524 0.8719602480199314 0.8849657897940558 1.0719323905155578 0.8666488120086389 1.1262271614279342 1.0062363624070212 1.0 18.897635322722934 -7.765643968360634 24.997851107098835 1.049673793579301 0.9546457974898788 0.10834216650049622 0.10999499432616533 240.32007309475796 1428751.2163064873 0.05995546971341684 0.030418578689364 1.7153629740598715e-08 7.765643968360634 -0.09502799608942225 KLS(ph)LGQYDNDAGGQLPFSK ddPTM_PC-9_Lapatinib_30min_R1 2 KLSLGQYDNDAGGQLPFSK 19 1 Q68CZ2;Q68CZ2-2;E9PCX8 Q68CZ2 TNS3 Tensin-3 1 KLS(0.953)LGQY(0.047)DNDAGGQLPFSK;KLS(0.946)LGQY(0.054)DNDAGGQLPFSK 72.793 0.0024522 121519000.0 941890.0 781920.0 862010.0 808350.0 808670.0 912070.0 863540.0 889500.0 1048360.0 919590.0 True False 928458.4758785275 780109.5122810203 791138.8652548252 867798.7555765518 761105.6205063914 873062.8922390154 908249.8758663299 930829.4172793998 930282.6570797866 1078539.9062233467 0.8608475871139997 0.7233014817343933 0.733527670779568 0.8046051430913358 0.7056814644638468 0.8094859422459046 0.8421105891637237 0.8630458751765847 0.8625389303742104 1.0 20.040648126856766 -8.382241767631937 0.5866906231714466 0.9984766595541154 0.7611079771205951 0.6962878938843157 0.04559892391152773 0.4447840065260639 0.36882228104181225 0.04660900731934723 0.021479488575383048 4.147231059282125e-09 8.382241767631937 -0.23736868243352027 KLS(ph)LSEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KLSLSEGK 8 1 K7EPU6;K7EMM8;Q49A26-4;Q49A26-2;Q49A26-3;Q49A26 K7EPU6 GLYR1 Putative oxidoreductase GLYR1 1 KLS(0.959)LS(0.041)EGK;KLS(0.986)LS(0.014)EGK 66.56 0.022334 60116000.0 329650.0 355110.0 303920.0 371890.0 340340.0 298160.0 323720.0 321290.0 294190.0 231770.0 True False 385453.23411571834 390362.9739597688 311166.6054230188 351054.20898364705 273652.8201511324 282523.9647193182 293054.8980701593 312856.4779348941 298491.97219720087 273788.0663096891 1.4078525748442292 1.4257852039402574 1.1365236243388703 1.2822115065693191 0.9995060187962915 1.0319075207600454 1.0703713350993063 1.1426958163363252 1.0902300316463338 1.0 18.06270003918076 -5.39423770203685 1.040726680217517 1.0671414798760224 1.478725585959434 0.7567980025601533 0.07454792679275928 0.4008324038509083 0.6588020579423784 0.026252497160545046 0.1469623619669899 4.034245265198977e-06 5.39423770203685 0.41158410608341156 KLS(ph)MGSDDAAYTQALLVHQK ddPTM_PC-9_AZD4547_30min_R2 4 KLSMGSDDAAYTQALLVHQK 20 1 A0A1B0GV57;Q9NYJ8 A0A1B0GV57 TAB2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 1 KLS(0.683)MGS(0.317)DDAAYTQALLVHQK;KLS(0.503)MGS(0.496)DDAAY(0.001)TQALLVHQK;KLS(0.918)MGS(0.082)DDAAYTQALLVHQK;KLS(0.5)MGS(0.5)DDAAYTQALLVHQK 147.0 1.0421e-14 31898800.0 159034.0 136660.0 163511.0 226281.0 210236.0 165788.0 153833.0 200360.0 165997.0 192247.0 True False 209603.50388730524 180832.67246804433 161342.73730381037 174115.41145659986 181048.36033751487 155421.25015173916 167523.83898599097 169398.96581476767 174771.2625304078 185516.49104543257 1.1298375832042544 0.9747525486764345 0.869694852433889 0.9385441179671697 0.9759151831584424 0.8377759264198074 0.9030131932851444 0.913120795138812 0.9420793889833046 1.0 17.501187911913547 -4.810267766932078 3.1447963513481287 0.9181398710363705 1.154462360592023 0.6553951734875869 0.0450553105489547 0.18578661770938165 2.866982257973531 0.011221003353216678 0.10590418841972866 1.5478619808309833e-05 4.810267766932078 0.2363224895556525 KLS(ph)MGSDDAAYTQALLVHQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLSMGSDDAAYTQALLVHQK 20 1 A0A1B0GV57;Q9NYJ8 A0A1B0GV57 TAB2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 1 KLS(0.738)MGS(0.234)DDAAY(0.025)T(0.003)QALLVHQK 84.156 0.00029747 14995000.0 57295.0 67649.0 62670.0 66113.0 71934.0 55406.0 55976.0 70914.0 45032.0 41861.0 True False 66993.91187216753 74364.7456433342 64164.29047729855 62408.90295123803 57839.049082539685 52500.411823311435 50673.5480488547 69052.58263959376 45690.507807825954 49450.06792850634 1.3547789655016378 1.5038350554108213 1.2975571756557678 1.2620589933560304 1.1696454930286835 1.0616853327525295 1.0247417277993882 1.3964102686254798 0.9239725994691077 1.0 15.593684882334683 -5.9059508015559 1.2794727621228428 1.1029087004725444 1.4307598178685186 0.5367021058222841 0.12461358286250246 0.37011907743608985 1.2261069412904584 0.043649856654872525 0.09153709675907012 1.2417929744081816e-06 5.9059508015559 0.32785111739597417 KLS(ph)MGSDDAAYTQALLVHQK ddPTM_PC-9_Lapatinib_30min_R1 3 KLSMGSDDAAYTQALLVHQK 20 1 A0A1B0GV57;Q9NYJ8 A0A1B0GV57 TAB2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 1 KLS(0.769)MGS(0.23)DDAAYT(0.001)QALLVHQK;KLS(0.989)MGS(0.011)DDAAYTQALLVHQK;KLS(0.916)MGS(0.084)DDAAYTQALLVHQK 109.38 3.184e-05 21295200.0 221767.0 165658.0 222989.0 193932.0 193188.0 159004.0 131353.0 128016.0 180222.0 155866.0 True False 218604.5619129131 165274.42907899732 204655.70518243205 208194.40621818716 181825.06166222144 152203.76957642764 138153.815624835 133964.0907053846 159923.5005382057 182807.23042161018 1.1958201073816566 0.9040913135537539 1.119516469400212 1.1388740245012534 0.9946272980717253 0.8325916279427161 0.7557349635799933 0.7328161495386252 0.8748204333568891 1.0 17.479963607672552 -6.663495351019047 3.247878494674812 0.8151518303492369 1.077811569938022 0.5833882936194561 0.09906022275893597 0.16590921161284003 3.4770485607722073 0.03398648296178896 0.033414568324547936 2.1702244349896153e-07 6.663495351019047 0.2626597395887851 KLS(ph)NPDIFSSTGK ddPTM_PC-9_AZD4547_30min_R2 2 KLSNPDIFSSTGK 13 1 Q6P0Q8;Q6P0Q8-2 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 KLS(0.983)NPDIFS(0.015)S(0.002)TGK;KLS(0.99)NPDIFS(0.002)S(0.006)T(0.002)GK 121.32 0.00029234 21414000.0 111412.0 113807.0 111522.0 142051.0 135565.0 136534.0 127485.0 145697.0 135240.0 131607.0 True False 146838.6984864394 150592.88713281666 110043.14541281966 109303.33661607238 116744.1397722333 127996.50739629862 138830.91802883075 123182.87643398985 142388.51030206788 126999.47898805338 1.1562149676240188 1.1857756294179969 0.8664850146603454 0.8606597246462275 0.9192489662356428 1.0078506495947044 1.0931613195191954 0.9699478880978516 1.1211739720244216 1.0 16.954463052828793 -10.358788307201763 15.18230607822838 0.999999988138826 1.0130789290480346 0.0 0.11127572806519354 0.0 0.0 0.1170143516330159 0.02838014891153477 4.377354232170942e-11 10.358788307201763 0.013078940909208692 KLS(ph)NPDIFSSTGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KLSNPDIFSSTGK 13 1 Q6P0Q8;Q6P0Q8-2 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 KLS(0.651)NPDIFS(0.315)S(0.027)T(0.008)GK;KLS(1)NPDIFSSTGK 97.2 0.0045115 13862400.0 62758.0 80868.0 63402.0 72945.0 79871.0 62882.0 73101.0 73052.0 58855.0 50654.0 True False 73381.68987299933 88896.04060200689 64913.744133424 68858.12814088083 64220.85090877088 59584.357222565595 66176.34407459127 71134.46240499208 59715.64303227916 59837.169223156605 1.2263563070527252 1.4856324548121285 1.0848398240788235 1.150758450555732 1.07326017828928 0.9957750006580663 1.1059404202059318 1.1888005954911298 0.9979690518041683 1.0 15.868754305371356 -5.280318639137686 24.228084741621437 1.0823773018857208 1.3559943557955585 0.6377144828795328 0.08465760840981265 280.3902063542383 359829.60269696394 0.021144236942898936 0.04415105062828153 5.244225535266184e-06 5.280318639137686 0.2736170539098377 KLS(ph)NPDIFSSTGK ddPTM_PC-9_Lapatinib_30min_R1 2 KLSNPDIFSSTGK 13 1 Q6P0Q8;Q6P0Q8-2 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 KLS(0.988)NPDIFS(0.01)S(0.001)TGK;KLS(0.997)NPDIFS(0.002)S(0.001)TGK 126.07 0.00019663 9572500.0 110533.0 93248.0 95075.0 85948.0 107135.0 93461.0 92831.0 97921.0 98135.0 94712.0 True False 108956.77915073013 93032.08998513993 87258.30050011327 92268.9026341229 100833.52993551409 89463.89089823207 97637.33495442859 102470.76713818545 87082.00289263709 111082.84300419272 0.9808605559961916 0.8375018812007586 0.785524552129259 0.8306314471141173 0.9077327083869128 0.8053799171745661 0.8789596333138805 0.9224715929742434 0.7839374698876789 1.0 16.761276480865035 -10.750647176996898 4.0492692298107995 1.000105444620371 0.8578588531384628 0.3259936924420961 0.060698655756186874 42784091.9059488 7.985470547058052 42327.182046383976 0.014382797338761369 1.7756314269158125e-11 10.750647176996898 -0.1422465914819082 KLS(ph)PIIEDSR ddPTM_PC-9_AZD4547_30min_R2 2 KLSPIIEDSR 10 1 O60566-3;O60566 O60566-3 BUB1B Mitotic checkpoint serine/threonine-protein kinase BUB1 beta 1 KLS(1)PIIEDSR;KLS(1)PIIEDSR 64.53399999999999 0.023456 55240000.0 116801.0 103918.0 143167.0 164234.0 155846.0 124118.0 147457.0 167601.0 126642.0 134920.0 True False 153941.28838827604 137507.46127275165 141268.51203634392 126372.38869000599 134209.47299777542 116356.88183905678 160580.38733793976 141702.11653783591 133336.03757523274 130196.49186645208 1.1823766230673862 1.0561533517646446 1.0850408487292336 0.9706282164624787 1.0308224981625436 0.8937021279990311 1.2333695404224385 1.088371234174156 1.0241139040213236 1.0 16.990331050167256 -4.415719306179292 1.7348679329140775 1.0424284967096427 1.3986844434600458 0.20215432918861054 0.08366576624855543 5.249997480200652 6.869481860461895 0.0233982662548466 4.235309020819837 3.839553238597044e-05 4.415719306179292 0.3562559467504032 KLS(ph)PIIEDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLSPIIEDSR 10 1 O60566-3;O60566 O60566-3 BUB1B Mitotic checkpoint serine/threonine-protein kinase BUB1 beta 1 KLS(0.974)PIIEDS(0.026)R 55.105 0.041905 25183000.0 35905.0 37553.0 37072.0 47128.0 41429.0 42457.0 40905.0 50088.0 37659.0 29553.0 True False 41983.007343924946 41281.01366086904 37955.9370763429 44487.57095103753 33311.28485056492 40230.480178723126 37030.182273445804 48773.24307262283 38209.69163117157 34910.724958580715 1.2025819398976971 1.1824736870931856 1.087228555733951 1.2743238934115266 0.9541848497871808 1.1523816886201577 1.0607107792055217 1.397084796448343 1.0944972261820647 1.0 15.091382695858323 -8.529268697590362 24.397415006991313 0.9999999814814549 1.1604936236420955 0.1683131686191034 0.11364011738771307 1031.3205570106506 3937680.7118405593 0.10681529630559712 0.02757959096996763 2.9561829130308902e-09 8.529268697590362 0.16049364216064066 KLS(ph)PIIEDSR ddPTM_PC-9_Lapatinib_30min_R1 1 KLSPIIEDSR 10 1 O60566-3;O60566 O60566-3 BUB1B Mitotic checkpoint serine/threonine-protein kinase BUB1 beta 1 KLS(1)PIIEDSR 59.79600000000001 0.03255 22385000.0 56738.0 48954.0 52360.0 52849.0 48789.0 46020.0 37110.0 44469.0 55589.0 41926.0 True False 55928.90571552514 48840.650020724825 48055.16291544492 56735.69175909586 45919.32694286458 44051.831877859615 39031.37421937545 46535.192082065856 49327.98144187902 49172.85323711658 1.1373939487674263 0.9932441744881096 0.9772701755523105 1.1538010919462105 0.9338349093032459 0.8958567375669078 0.793758581206629 0.9463594039920432 1.0031547529693752 1.0 15.58557444899741 -6.415977497346537 7.876538612518304 0.9159716908829826 1.0537144381501296 0.43112333832268646 0.07580283729984467 0.2867233043425302 18.94619962787813 0.024160087957142883 0.027375437899435348 3.8372712751987427e-07 6.415977497346537 0.13774274726714697 KLS(ph)PPPLPPR ddPTM_PC-9_Lapatinib_30min_R1 1 KLSPPPLPPR 10 1 F5GWN5;O00750 F5GWN5 PIK3C2B Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 1 KLS(1)PPPLPPR 59.227 0.033683 15175000.0 25621.0 22411.0 25196.0 28091.0 29185.0 27041.0 26565.0 25656.0 28814.0 21089.0 True False 25255.639841684042 22359.108706427727 23124.482139372627 30156.905848828963 27468.395679917656 25884.519465649762 27940.405716456706 26848.071421832792 25568.663895128582 24734.20555067384 1.0210815055265035 0.9039752120042761 0.9349191382758053 1.2192389113547815 1.1105428724461024 1.04650700879069 1.129626163218148 1.0854632612649797 1.033737018265865 1.0 14.594219941204477 -5.725826590154249 24.99912519119026 1.0936452703903672 0.9483900812677858 0.4947716219949395 0.0628009082720801 137.2044304444686 96312.48348571082 0.016755661161632355 0.029020396501666938 1.880067360787661e-06 5.725826590154249 -0.1452551891225814 KLS(ph)PQDPSEDVSSVDPLK ddPTM_PC-9_AZD4547_30min_R2 4 KLSPQDPSEDVSSVDPLK 18 1 H7C0Y9;F8WDN8;H7BZZ1;Q53T59 H7C0Y9 HS1BP3 HCLS1-binding protein 3 1 KLS(0.997)PQDPS(0.003)EDVSSVDPLK;KLS(1)PQDPSEDVSSVDPLK;KLS(1)PQDPSEDVSSVDPLK;KLS(1)PQDPSEDVSSVDPLK 140.12 1.9347e-05 91809000.0 318952.0 359878.0 358611.0 283876.0 334686.0 414947.0 414897.0 416687.0 423391.0 345780.0 True False 420372.10138626647 476201.525702143 353855.58382773516 218432.77404047977 288220.6260008821 389000.2984939419 451822.0292380111 352297.598664694 445770.5838901424 333674.34744724096 1.259827447336909 1.427144547806264 1.0604818336647386 0.6546286093359854 0.8637781963339397 1.165808224306032 1.354080805715672 1.0558126549431484 1.335945023345331 1.0 18.348081252256968 -5.2738123778249975 22.25121569852638 1.05591831214729 1.3434859651333364 0.24376271829272644 0.19861724647021337 235.2178153553377 423011.9541506762 0.057640176023928034 0.1218131347670832 5.323381882238357e-06 5.2738123778249975 0.2875676529860465 KLS(ph)PQDPSEDVSSVDPLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 KLSPQDPSEDVSSVDPLK 18 1 H7C0Y9;F8WDN8;H7BZZ1;Q53T59 H7C0Y9 HS1BP3 HCLS1-binding protein 3 1 KLS(0.999)PQDPSEDVSSVDPLK;KLS(0.988)PQDPS(0.009)EDVSS(0.002)VDPLK;KLS(1)PQDPSEDVSSVDPLK;KLS(1)PQDPSEDVSSVDPLK 212.24 1.5922000000000001e-21 76937000.0 427000.0 574183.0 426256.0 481154.0 507397.0 365869.0 501721.0 354341.0 332508.0 339003.0 True False 499282.6663655754 631184.0935967494 436419.5596248829 454196.50130231533 407976.20022984094 346682.1855644359 454194.35473451944 345039.924205323 337370.3004566661 400461.56035372923 1.2467680191940447 1.5761415228947868 1.0897913878160785 1.1341825190440795 1.0187649468015707 0.8657065243870353 1.1341771588097689 0.861605603046015 0.8424536431378473 1.0 18.61130424179349 -5.665919426283645 1.2709591224294559 0.9483036909431075 1.4193489673088333 0.6374703267130141 0.12630394705419 0.3026835954630585 0.9389478517081696 0.04171455061000365 0.12239370368694513 2.1581447679459118e-06 5.665919426283645 0.4710452763657258 KLS(ph)PQDPSEDVSSVDPLK ddPTM_PC-9_Lapatinib_30min_R1 4 KLSPQDPSEDVSSVDPLK 18 1 H7C0Y9;F8WDN8;H7BZZ1;Q53T59 H7C0Y9 HS1BP3 HCLS1-binding protein 3 1 KLS(0.992)PQDPS(0.008)EDVSSVDPLK;KLS(1)PQDPSEDVSSVDPLK;KLS(0.999)PQDPS(0.001)EDVSSVDPLK;KLS(0.998)PQDPS(0.002)EDVSSVDPLK 135.33 3.1553e-05 100893000.0 305710.0 551488.0 507334.0 497796.0 617520.0 571658.0 629020.0 626400.0 536981.0 512623.0 True False 301350.5193396526 550211.063419321 465622.95688587305 534405.578438776 581198.6876910323 547209.5199398851 661587.5777815026 655504.8307856268 476500.545119388 601229.2025227875 0.5012240225111669 0.9151436109733329 0.7744516649093159 0.8888549927321955 0.9666840620054612 0.9101512661789661 1.1003916227046997 1.0902744378268654 0.7925439135690152 1.0 19.19755555905973 -4.245011431634404 0.6706480146337229 0.9851566480967848 3.817596470746681e-17 0.594156328568094 0.10607219423357425 4.387996559868604 0.892851983225078 0.04520255737248541 3.8806249475793066 5.688379575171688e-05 4.245011431634404 -0.9851566480967848 KLS(ph)PTEPK ddPTM_PC-9_Lapatinib_30min_R1 1 KLSPTEPK 8 1 O14828-2;O14828 O14828-2 SCAMP3 Secretory carrier-associated membrane protein 3 1 KLS(0.894)PT(0.106)EPK 97.734 0.008406100000000001 60231000.0 134800.0 121160.0 99390.0 101810.0 97139.0 91652.0 69440.0 76190.0 87280.0 63467.0 True False 132877.7272807078 120879.46146404816 91218.53785649482 109297.44702820363 91425.47500262196 87732.25761124716 73035.26342747048 79730.06554526961 77449.60730085445 74437.18638553827 1.7850987353617038 1.6239122854263706 1.22544311903515 1.4683178171473452 1.2282231427863881 1.1786079226161061 0.9811663628605372 1.0711053092780471 1.0404693011865562 1.0 16.183735904259443 -1.5228787452803376 0.28277076287438263 0.9651186743656014 7.527437934795438 0.8825625230592216 0.0899921462022715 16.31969884173101 0.2305159079091506 0.10000583924242866 53.089237218907456 0.029999999999999995 1.5228787452803376 6.562319260429837 KLS(ph)QRPTVAELLAR ddPTM_PC-9_Lapatinib_30min_R1 1 KLSQRPTVAELLAR 14 2 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 KLS(0.976)QRPT(0.024)VAELLAR 44.968 0.043261 4597700.0 12166.0 8351.1 10970.0 9712.2 8070.1 7237.6 7557.6 7900.4 8670.6 6945.1 True False 11992.510609028843 8331.76354104005 10068.088945424575 10426.467586949439 7595.432584427058 6928.064719669643 7948.895548379197 8267.481425828171 7694.02572253425 8145.551281235954 1.472277344402057 1.0228606086162706 1.2360230262888858 1.2800198816460453 0.9324639084801852 0.8505335588063995 0.975857283802292 1.014968924801087 0.9445678330278473 1.0 12.991796626603932 -6.264799392448233 24.976068006215133 0.9498267053259559 1.2351733071308455 0.6392623418035057 0.10996984321140499 192.1521585958916 1428326.3239556372 0.03288086867651723 0.03881456497049088 5.435013254544645e-07 6.264799392448233 0.2853466018048896 KLS(ph)SAMSAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLSSAMSAAK 10 1 A0A5K1VW95;P40925;P40925-3;B9A041;P40925-2;B8ZZ51 A0A5K1VW95 MDH1 Malate dehydrogenase, cytoplasmic 1 KLS(0.88)S(0.118)AMS(0.003)AAK 49.62 0.044788999999999995 48735000.0 114570.0 102240.0 95569.0 129700.0 128640.0 114010.0 121150.0 115560.0 106090.0 99195.0 True False 133964.4381393531 112389.7115193793 97847.72740745085 122433.3294930732 103433.9154499665 108031.11489686566 109673.7949499565 112526.67244594113 107641.36554743844 117178.26827281232 1.1432532679819054 0.95913442975378 0.835033055614404 1.0448467219879554 0.8827056157644653 0.9219381416812679 0.9359567824864586 0.9603032550708002 0.9186120185428049 1.0 16.83834550868385 -4.772449773382005 4.72924275964003 0.9349371912423908 1.1566386424152388 0.5545226825145564 0.05492197112686562 0.12251087791227054 6.5147494089626505 0.012816058732813853 0.08979741291988852 1.6886911471182554e-05 4.772449773382005 0.221701451172848 KLS(ph)SIGIQVDCIQPVPK ddPTM_PC-9_AZD4547_30min_R2 2 KLSSIGIQVDCIQPVPK 17 1 Q9Y2H0-3;Q9Y2H0 Q9Y2H0-3 DLGAP4 Disks large-associated protein 4 1 KLS(0.785)S(0.215)IGIQVDCIQPVPK;KLS(0.5)S(0.5)IGIQVDCIQPVPK 87.208 0.0013452 22553100.0 228100.0 242770.0 250500.0 240520.0 289500.0 205148.0 258110.0 320040.0 290370.0 257650.0 True False 300631.05522526207 321240.65487389953 247178.20632620784 185071.82999695698 249307.92213374804 192320.06312959333 281081.28997467546 270585.1717875732 305718.36539789615 248629.75192255672 1.2091515713650502 1.2920443043918561 0.9941618185871778 0.7443671908364499 1.002727630969131 0.7735199091921117 1.1305215397641821 1.0883056822252517 1.229612960773582 1.0 17.92363941918952 -5.268404565634779 23.359250392570797 0.9867532667473365 1.2505979517322288 0.3433864462254449 0.14074930471067787 224.64050400688 753387.8334100005 0.03905298078690898 0.08449257777526001 5.390082771367179e-06 5.268404565634779 0.2638446849848922 KLS(ph)SIGIQVDCIQPVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLSSIGIQVDCIQPVPK 17 1 Q9Y2H0-3;Q9Y2H0 Q9Y2H0-3 DLGAP4 Disks large-associated protein 4 1 KLS(0.5)S(0.5)IGIQVDCIQPVPK 55.988 0.023101 9961500.0 143310.0 152040.0 122500.0 113500.0 139610.0 81974.0 84971.0 95146.0 63706.0 71726.0 True False 167569.5524984789 167133.52640264534 125420.86458383694 107140.96297196501 112254.42269877046 77675.13913302036 76921.93174323329 92648.51831552002 64637.57973008884 84729.35601729638 1.9777036009133813 1.9725574967019368 1.48025277754069 1.2645081705813226 1.324858679155489 0.9167441225112583 0.907854554300291 1.093464209696189 0.7628711319001873 1.0 16.370574283498378 -5.437467546877177 0.6754502916547654 0.9195211152250168 2.3155996603904097 0.9141486087951705 0.11933796981354806 0.40634506839694545 0.2467452144815861 0.05956689574740047 0.38561892929913055 3.6520141630431747e-06 5.437467546877177 1.396078545165393 KLS(ph)SIGIQVDCIQPVPK ddPTM_PC-9_Lapatinib_30min_R1 2 KLSSIGIQVDCIQPVPK 17 1 Q9Y2H0-3;Q9Y2H0 Q9Y2H0-3 DLGAP4 Disks large-associated protein 4 1 KLS(0.5)S(0.5)IGIQVDCIQPVPK;KLS(0.5)S(0.5)IGIQVDCIQPVPK 72.585 0.0054174 17392100.0 151977.0 264970.0 220370.0 220190.0 214800.0 171105.0 171783.0 139302.0 205988.0 184215.0 True False 149809.78011083155 264356.47824470873 202252.02925279975 236383.50713230786 202165.88631304813 163787.23801523613 180677.08319932566 145774.47946695346 182787.46229019752 216056.3172989421 0.69338301227985 1.2235535695026083 0.9361079175155878 1.0940828302892918 0.9357092115632298 0.758076598096482 0.8362499438020845 0.6747059344960298 0.8460176706487468 1.0 17.72104788913031 -6.600802730758497 4.864312431512523 0.8045797374771164 1.001911299626797 0.2108954256952198 0.14744485357235806 0.2609088976201198 11.25283923740411 0.04628985782553766 0.04643755910698398 2.5072478596449154e-07 6.600802730758497 0.1973315621496805 KLS(ph)SSDAPAQDTGSSAAAVETDASR ddPTM_PC-9_AZD4547_30min_R2 4 KLSSSDAPAQDTGSSAAAVETDASR 25 1 H0YHT2;A0A1B0GV47;Q7Z4S6-6;Q7Z4S6-3;Q7Z4S6-5;Q7Z4S6-2;Q7Z4S6;Q7Z4S6-4;H0YIM6 H0YHT2 KIF21A Kinesin-like protein KIF21A 1 KLS(0.621)S(0.189)S(0.189)DAPAQDTGSSAAAVETDASR;KLS(0.735)S(0.035)S(0.231)DAPAQDTGSSAAAVETDASR;KLS(0.516)S(0.242)S(0.242)DAPAQDTGSSAAAVETDASR;KLS(0.595)S(0.202)S(0.202)DAPAQDTGSSAAAVETDASR 201.95 2.5052000000000003e-26 347529000.0 248534.0 234488.0 299254.0 414094.0 358259.0 302285.0 234271.0 298812.0 258564.0 264083.0 True False 327562.6421716585 310281.6603372366 295285.6964309101 318631.0259885245 308520.92185048136 283383.0711638867 255120.66515693694 252637.4714166609 272231.16517113225 254837.53455060895 1.2853783205417366 1.217566560139581 1.15872136713153 1.2503300447887773 1.210657301305869 1.112014647542467 1.001111023958175 0.9913668010568862 1.0682538019809207 1.0 17.959218259573944 -6.959247984823438 2.5059637604093936 1.0145400778004512 1.2234789000557291 0.8827098676200951 0.03599843839767482 0.09506041285815149 1.2080619881523351 0.015043963207978104 0.012316382214391014 1.0983784794610644e-07 6.959247984823438 0.20893882225527793 KLS(ph)SSDAPAQDTGSSAAAVETDASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KLSSSDAPAQDTGSSAAAVETDASR 25 1 H0YHT2;A0A1B0GV47;Q7Z4S6-6;Q7Z4S6-3;Q7Z4S6-5;Q7Z4S6-2;Q7Z4S6;Q7Z4S6-4;H0YIM6 H0YHT2 KIF21A Kinesin-like protein KIF21A 1 KLS(0.614)S(0.193)S(0.193)DAPAQDTGSSAAAVETDASR;KLS(0.61)S(0.161)S(0.229)DAPAQDTGSSAAAVETDASR;KLS(0.643)S(0.178)S(0.178)DAPAQDTGSSAAAVETDASR 172.37 1.5088e-11 162214000.0 129047.0 142952.0 131509.0 123426.0 172468.0 174078.0 187694.0 202239.0 175072.0 147250.0 True False 150892.10830556948 157143.32982314454 134644.6733106596 116510.841372491 138674.13347189702 164949.04323319503 169914.26553311697 196930.44053993298 177632.09679631607 173945.25936964108 0.8674689316189832 0.9034067981652105 0.7740634829520356 0.6698132607621143 0.7972285877432772 0.9482813376515844 0.9768260782091331 1.1321403138756856 1.0211953889403809 1.0 17.408273835331343 -7.027837713841881 2.118741885946415 1.048421695181821 0.7991650600065123 0.7120153753389038 0.06923948460117932 0.18721136606323954 1.678237959940459 0.033729531318794505 0.025850887497285393 9.379124183958362e-08 7.027837713841881 -0.24925663517530872 KLS(ph)SSDAPAQDTGSSAAAVETDASR ddPTM_PC-9_Lapatinib_30min_R1 4 KLSSSDAPAQDTGSSAAAVETDASR 25 1 H0YHT2;A0A1B0GV47;Q7Z4S6-6;Q7Z4S6-3;Q7Z4S6-5;Q7Z4S6-2;Q7Z4S6;Q7Z4S6-4;H0YIM6 H0YHT2 KIF21A Kinesin-like protein KIF21A 1 KLS(0.665)S(0.115)S(0.22)DAPAQDTGSSAAAVETDASR;KLS(0.615)S(0.193)S(0.193)DAPAQDTGSSAAAVETDASR;KLS(0.889)S(0.055)S(0.055)DAPAQDTGSSAAAVETDASR;KLS(0.732)S(0.036)S(0.232)DAPAQDTGSSAAAVETDASR 193.73 2.2288000000000005e-25 272202000.0 258145.0 233760.0 222794.0 202788.0 259089.0 344602.0 335649.0 341214.0 380367.0 347008.0 True False 254463.80496200427 233218.7430821714 204476.7373297106 217701.7060009376 243849.89440857226 329864.1757664967 353027.2628768301 357068.04810294806 337526.0630179211 406987.87044090347 0.6252368275406713 0.5730361025981383 0.5024148191644978 0.5349095681035754 0.5991576460114194 0.8105012451824274 0.8674147032794466 0.8773432184013847 0.8293270820387545 1.0 18.6346262725757 -6.80379323180561 2.5694753465631703 0.8818943697313605 0.5549082759833938 0.9061727776032132 0.05049756399692694 0.08041989592885919 1.0862882862711942 0.01932263283755226 0.017445234161169616 1.5711106342109846e-07 6.80379323180561 -0.3269860937479667 KLS(ph)TTGSSDSITPVAPTSAVSSSGSPASVMTNMR ddPTM_PC-9_AZD4547_30min_R2 1 KLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMR 34 1 Q15714-4;Q15714 Q15714-4 TSC22D1 TSC22 domain family protein 1 1 KLS(0.202)T(0.17)T(0.17)GS(0.202)S(0.202)DS(0.04)IT(0.014)PVAPTSAVSSSGSPASVMTNMR 53.047 0.013356 0.0 6092.4 8130.0 5491.1 8754.6 11485.0 8155.7 5899.6 9176.9 5703.7 9736.0 True False 8029.65647020773 10757.863509184837 5418.284426178998 6736.3622272216835 9890.505995530553 7645.722789722659 6424.652970960415 7758.820969183167 6005.185937665665 9395.145603407767 0.8546601414346625 1.1450448948106553 0.57671106493695 0.717004558692342 1.0527251426463375 0.8137950290998615 0.6838268657198981 0.8258329670131903 0.6391796562990455 1.0 13.197699804975494 -6.996839925743755 24.996575068805907 0.7692837929569066 0.8671858929756415 0.044575056367053056 0.17302460561413058 302.97584320242623 2396548.5010380982 0.061818828008154546 0.05425118168256049 1.0073028767609268e-07 6.996839925743755 0.0979021000187349 KLSASS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 KLSASSPR 8 1 A0A0A0MRY2;B0QZE2;B7Z2J6;E7ENI9;J3QKD2;Q15326-4;Q15326-5;Q15326-2;Q15326-6;Q15326-3;Q15326 A0A0A0MRY2 ZMYND11 Zinc finger MYND domain-containing protein 11 1 KLS(0.005)AS(0.239)S(0.756)PR;KLSAS(0.033)S(0.967)PR 58.782 0.034982 30526000.0 199902.0 173470.0 237119.0 299000.0 261642.0 220758.0 203924.0 235204.0 193577.0 196669.0 True False 263466.6777800968 229540.7851092613 233974.6471291978 230070.16950395028 225317.52456966534 206953.96736191772 222072.84094686623 198858.6262502322 203809.08502472207 189783.67817138473 1.3882472945970223 1.2094864390918476 1.2328491542771465 1.2122758485910716 1.1872334161749762 1.0904729498130357 1.1701366686882455 1.047817326370144 1.0739020709708853 1.0 17.533996397071185 -1.5228787454592303 0.164837741471421 0.9712197700344731 2.435510952528604 0.8503650439513973 0.041273945354167355 22.006549562058744 0.2329540422281753 0.11129913250123202 7.880724493571224 0.029999999987642526 1.5228787454592303 1.4642911824941307 KLSASS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 KLSASSPR 8 1 A0A0A0MRY2;B0QZE2;B7Z2J6;E7ENI9;J3QKD2;Q15326-4;Q15326-5;Q15326-2;Q15326-6;Q15326-3;Q15326 A0A0A0MRY2 ZMYND11 Zinc finger MYND domain-containing protein 11 1 KLS(0.071)AS(0.223)S(0.705)PR 53.597 0.044527 15448000.0 134050.0 123350.0 146600.0 123850.0 122620.0 120040.0 121750.0 105980.0 129610.0 90259.0 True False 132138.4224182409 123064.39065360112 134547.1138923649 132958.34215148832 115407.73268019535 114906.16902690723 128053.6192726749 110904.21769901157 115011.95694619331 105860.14788744246 1.2482357625150802 1.1625185975032961 1.2709892870679182 1.2559810731877916 1.090190548410196 1.0854525647279758 1.209648973935215 1.0476484296709305 1.0864518824258744 1.0 16.691800048979736 -7.231745208699848 0.33395978994258446 0.994710586984803 1.2667151395593632 0.6124707921900945 0.05698993311673761 1.1716380653230365 0.3336681307081794 0.07917456156564345 0.1146215602229187 5.86482140152554e-08 7.231745208699848 0.27200455257456024 KLSDAS(ph)DER ddPTM_PC-9_Lapatinib_30min_R1 1 KLSDASDER 9 1 Q658Y4;E7ER68 Q658Y4 FAM91A1 Protein FAM91A1 1 KLS(0.003)DAS(0.997)DER 58.511 0.035792000000000004 11129000.0 53057.0 55444.0 44026.0 50121.0 64148.0 60571.0 62647.0 65576.0 52093.0 55998.0 True False 52300.39745053786 55315.62282446922 40406.3522252746 53807.065538754585 60374.94075982039 57980.51952789733 65890.55512587473 68622.90035695769 46225.73777639111 65677.17968735514 0.796325263957814 0.8422350516235575 0.6152266649941739 0.8192657753407473 0.9192681696629615 0.8828107388883563 1.0032488520295075 1.0448515098185571 0.7038325640114382 1.0 16.003104555714685 -6.15876534084775 3.5826881583046877 0.9303810604066819 0.7553495845758237 0.3672409982342856 0.10328194059249551 0.26426206269080255 6.277730830152326 0.031337263713491846 0.0414341212015976 6.938005809372581e-07 6.15876534084775 -0.1750314758308582 KLSFLS(ph)WGTNK ddPTM_PC-9_AZD4547_30min_R2 1 KLSFLSWGTNK 11 1 Q8IUC4-2;A8MT19;Q8IUC4 Q8IUC4-2 RHPN2;RHPN2P1 Rhophilin-2;Putative rhophilin-2-like protein RHPN2P1 1 KLS(0.277)FLS(0.723)WGTNK 73.758 0.010976 6973800.0 42707.0 38610.0 50431.0 62710.0 45155.0 42727.0 31549.0 44337.0 42773.0 41327.0 True False 56286.93763921629 51089.92744029848 49762.251988969976 48253.17835984187 38886.007682035895 40055.27393558862 34356.79988148862 37485.7354129035 45033.89345718984 39880.15430895983 1.411402202788628 1.2810865034396361 1.2477948706880995 1.2099546552908118 0.975071645429903 1.0043911471673883 0.8615011771348569 0.9399596381321329 1.1292306721860434 1.0 15.283383371540834 -6.011473743547784 1.4484522273271048 0.9694886134602192 1.3382993454061702 0.8081279589522647 0.07348363446847585 0.17294304515525166 0.7342645439728301 0.026469718804021984 0.0463564706068784 9.739266649299472e-07 6.011473743547784 0.36881073194595104 KLSGDQPAAR ddPTM_PC-9_Lapatinib_30min_R1 1 KLSGDQPAAR 10 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 0 68.536 0.025775 1550300.0 14508.0 9658.0 9674.9 10645.0 7505.9 7326.8 8011.9 10649.0 12829.0 9754.6 False True 14301.113259558644 9635.637494385745 8879.46706819401 11427.868810679014 7064.417719167172 7013.449843605001 8426.716979472221 11143.791416085802 11384.062924640953 11440.669612812515 1.2500241457495365 0.842226707044726 0.7761317622746321 0.9988811142558329 0.6174828885239081 0.6130279154072041 0.7365580219216418 0.9740506275616738 0.9950521525323861 1.0 13.481883873869634 -4.7620046694943285 5.781614770746099 0.8230975510192043 1.267690157815306 0.41568117279414396 0.14513928374170684 0.1437988811083976 17.015888478179544 0.038448776360930505 0.2546581291867221 1.7297977604886797e-05 4.7620046694943285 0.4445926067961016 KLSLGQY(ph)DNDAGGQLPFSK ddPTM_PC-9_AZD4547_30min_R2 1 KLSLGQYDNDAGGQLPFSK 19 1 Q68CZ2;Q68CZ2-2;E9PCX8 Q68CZ2 TNS3 Tensin-3 1 KLS(0.453)LGQY(0.547)DNDAGGQLPFSK 88.28299999999999 0.0076479 116020000.0 449730.0 431410.0 575000.0 763770.0 741520.0 548820.0 488800.0 683930.0 572080.0 591230.0 True False 592734.7850348818 570854.8458176418 567375.1243016741 587694.6266288699 638572.7475668959 514502.19864090113 532302.2530689278 578244.3336479033 602318.9808755327 570531.2176564052 1.0389173575281 1.000567240058425 0.9944681495822516 1.0300832074412467 1.1192599594987769 0.9017949986231134 0.9329940879580401 1.013519183092525 1.0557160804446486 1.0 19.12194630280161 -6.768341425851069 24.999999160665396 0.9786616705506691 1.0319447967330275 0.22996358599032085 0.05066246723953518 288.5060125257786 1044994.4858620199 0.018991650205721147 0.017114896129230218 1.7047416588166732e-07 6.768341425851069 0.05328312618235842 KLSMGS(ph)DDAAYTQALLVHQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLSMGSDDAAYTQALLVHQK 20 1 A0A1B0GV57;Q9NYJ8 A0A1B0GV57 TAB2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 1 KLS(0.154)MGS(0.822)DDAAY(0.008)T(0.016)QALLVHQK 68.375 0.0019054000000000002 14652000.0 22657.0 28280.0 28805.0 26438.0 26323.0 21917.0 21127.0 28545.0 17932.0 16411.0 True False 26492.38260385204 31087.45150399106 29491.820443570818 24956.76457315246 21165.19711123658 20767.633937326584 19125.697613765795 27795.72399592751 18194.221575988973 19386.18439059549 1.3665599207187913 1.6035879406507667 1.5212803019596635 1.2873479417259304 1.0917670380512896 1.0712594865960965 0.9865632776630321 1.4337903444997464 0.9385148314598332 1.0 14.242741258163997 -5.978178470670211 2.801159368689096 1.1035446924830372 1.5087227348865349 0.6357805616294594 0.1388472925974634 0.17042512518147257 2.7196633694359 0.04126016477660563 0.06263039533176261 1.0515296653159388e-06 5.978178470670211 0.40517804240349764 KLSS(ph)GET(ph)VT(ph)Y(ph)QK ddPTM_PC-9_AZD4547_30min_R2 1 KLSSGETVTYQK 12 1 E2QRF0;Q70EL2-3;Q70EL2 E2QRF0 USP45 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 45 4 KLS(0.039)S(0.963)GET(1)VT(0.999)Y(0.999)QK 45.14 0.044610000000000004 0.0 23657.0 29531.0 32560.0 40277.0 36896.0 29368.0 41411.0 40052.0 29195.0 30247.0 True False 31179.43390383169 39076.31823982012 32128.23312567393 30991.75992344684 31773.62727131868 27531.61431741911 45096.4987762631 33862.883703399224 30738.188097226193 29188.061736470292 1.0682255706233892 1.338777428683951 1.100731984732303 1.061795750716905 1.0885829815694046 0.9432491463802318 1.5450323212080683 1.1601621241292557 1.0531082322201282 1.0 14.833090789909104 KLSS(ph)SDAPAQDTGSSAAAVETDASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLSSSDAPAQDTGSSAAAVETDASR 25 1 H0YHT2;A0A1B0GV47;Q7Z4S6-6;Q7Z4S6-3;Q7Z4S6-5;Q7Z4S6-2;Q7Z4S6;Q7Z4S6-4;H0YIM6 H0YHT2 KIF21A Kinesin-like protein KIF21A 1 KLS(0.273)S(0.363)S(0.363)DAPAQDTGSSAAAVETDASR 65.741 0.00038091 40122000.0 15302.0 15510.0 11131.0 14747.0 21966.0 19164.0 19963.0 19487.0 14098.0 16584.0 True False 17892.326371723695 17049.730297980957 11396.405254552572 13920.773400419075 17661.91998425038 18159.0061037061 18071.960120396016 18975.48689818321 14304.156579204357 19590.547921128233 0.9133142392830667 0.8703039019951542 0.5817297862435817 0.7105862202764448 0.9015531395730977 0.9269269127547868 0.9224836483978871 0.968604194970898 0.7301560240577779 1.0 14.257870127948213 -6.279385491777091 20.844750494115484 0.9083594664377732 0.7628454837641507 0.28920273950437425 0.1068159824053475 126.0839402546177 146447.66171690883 0.03455141254881448 0.039331796822785405 5.255505660954543e-07 6.279385491777091 -0.14551398267362248 KLSSERPS(ph)SDGEGVVENGITTCNGK ddPTM_PC-9_AZD4547_30min_R2 1 KLSSERPSSDGEGVVENGITTCNGK 25 2 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 KLS(0.012)S(0.012)ERPS(0.585)S(0.392)DGEGVVENGITTCNGK 82.146 0.00012371 10637000.0 32254.0 21275.0 35262.0 46398.0 45594.0 37014.0 33214.0 35774.0 35062.0 42068.0 True False 42510.10107512312 28151.72769469954 34794.40284021851 35701.65794195414 39264.06010972746 34699.50872871668 36169.98165595624 30245.9503047389 36915.30573950831 40595.21212450266 1.0471703151777514 0.6934740877411891 0.857106072841953 0.8794548931647325 0.9672091376024186 0.8547685037904404 0.8909913204795051 0.7450620090856207 0.9093512216734245 1.0 15.309021962832835 -8.535203374352545 23.327847006219624 1.0000000088122547 0.8625976965867849 0.1552605746137864 0.09413280787481304 1400.6375785317198 2651104.796639774 0.0868905834589858 0.02243505221603216 2.9160611414142014e-09 8.535203374352545 -0.13740231222546984 KLSSERPS(ph)SDGEGVVENGITTCNGK ddPTM_PC-9_Lapatinib_30min_R1 2 KLSSERPSSDGEGVVENGITTCNGK 25 2 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 KLS(0.052)S(0.052)ERPS(0.447)S(0.447)DGEGVVENGIT(0.001)T(0.001)CNGK;KLS(0.015)S(0.015)ERPS(0.485)S(0.485)DGEGVVENGITTCNGK 67.992 0.0062561000000000005 11512000.0 54888.0 39094.8 50246.0 46387.7 45025.0 46014.3 31381.3 31408.3 38693.0 28923.7 True False 54105.287054773595 39004.27839257738 46114.96783516895 49799.206202830916 42376.71802255586 44046.37565357227 33006.07016411985 32867.644279636355 34334.98688464669 33923.12300659231 1.5949382680438728 1.1497844224129259 1.3593962981004841 1.4680018167299453 1.249198607519737 1.2984174730909268 0.9729667329775549 0.968886156892134 1.0121410955581638 1.0 15.049981371936523 -7.1865003243197005 2.9908803376681705 0.9813525860557971 1.3543059779891562 0.7166096387116702 0.11261836531300436 0.1460162318109832 2.5557402163299114 0.04699381004888685 0.03393920299206134 6.508781247815574e-08 7.1865003243197005 0.3729533919333591 KLSSERPSS(ph)DGEGVVENGITTCNGK ddPTM_PC-9_Lapatinib_30min_R1 1 KLSSERPSSDGEGVVENGITTCNGK 25 2 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 KLS(0.06)S(0.06)ERPS(0.393)S(0.486)DGEGVVENGITTCNGK 64.954 0.0025071 9690000.0 20674.0 18597.0 19445.0 18792.0 19885.0 17037.0 15856.0 14045.0 19166.0 13172.0 True False 20379.18496885274 18553.939789096275 17846.30715987063 20174.02636827431 18715.40339541419 16308.367225186763 16676.946095996147 14697.581973793322 17007.323253072616 15448.762649413251 1.319146745362597 1.2009984365835902 1.155193303494014 1.3058668079828728 1.2114499924772295 1.0556422928671352 1.0795004411974407 0.9513759973748798 1.1008857886569032 1.0 13.915203671333341 -6.7608515180754445 3.5767312473959785 1.0333276248398384 1.238664966519154 0.7507052599958803 0.05825026397021502 0.11761347075820668 3.205176873025421 0.02067195493823566 0.019290287604924506 1.7343968732758377e-07 6.7608515180754445 0.2053373416793156 KLSSWDQAET(ph)PGHTPSLR ddPTM_PC-9_Lapatinib_30min_R1 1 KLSSWDQAETPGHTPSLR 18 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 KLSSWDQAET(0.98)PGHT(0.015)PS(0.005)LR 110.16 0.00019682 6233600.0 37778.0 19592.0 33876.0 24088.0 23903.0 22894.0 22017.0 18889.0 29024.0 16311.0 True False 37239.2787923633 19546.6359277289 31090.846045141552 25859.511875212393 22497.07253510613 21914.876988520613 23156.932529991627 19766.651897684736 25755.01148373054 19130.334616958662 1.9466088564572948 1.0217613188219508 1.6252118254941623 1.3517542893519723 1.1759894944630462 1.145556386091308 1.2104823566161496 1.0332622138329977 1.3462917402866144 1.0 14.22357448825725 KLSSWDQAETPGHTPS(ph)LR ddPTM_PC-9_AZD4547_30min_R2 1 KLSSWDQAETPGHTPSLR 18 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 KLSSWDQAET(0.001)PGHT(0.273)PS(0.726)LR 97.662 0.0035153 0.0 13145.0 9124.7 18921.0 26235.0 19636.0 17135.0 9843.4 16309.0 15609.0 17585.0 True False 17324.836567014732 12074.080831766163 18670.09517723823 20186.926076709486 16909.880342032033 16063.545741248172 10719.443530807475 13788.81879353684 16434.059873594928 16969.354502457434 1.0209484729961777 0.7115226940434088 1.1002242409712462 1.1896107228937962 0.9964952019585195 0.9466209064653528 0.6316942420676713 0.8125717917873658 0.9684552156191335 1.0 14.050644066774435 -7.014052029056334 23.952897996336592 0.8306464717363217 1.0000439279915005 0.1821152629716365 0.1473927786299234 618.7635419978501 1054735.0368223644 0.057508658214682554 0.04646336326214898 9.681618622349856e-08 7.014052029056334 0.16939745625517888 KLSVPT(ph)SDEEDEVPAPKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLSVPTSDEEDEVPAPKPR 19 2 Q5STZ8;Q8NE71-2;Q8NE71;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 KLS(0.005)VPT(0.498)S(0.498)DEEDEVPAPKPR 61.495 0.0081914 22271000.0 28566.0 24670.0 26588.0 39699.0 30835.0 36119.0 31580.0 32051.0 28117.0 24821.0 True False 33401.659595782185 27119.074561649926 27221.958755551517 37474.79373589455 24793.103100899585 34224.85605613444 28588.5137805994 31209.695210841586 28528.157932862014 29320.850817072103 1.1391777068192723 0.9249074909470161 0.9284163998304407 1.2780936668479894 0.8455792519657639 1.1672531697547799 0.9750233360879726 1.0644198357528458 0.9729648744111974 1.0 14.839639346996666 -8.272752114379962 23.249092010929413 0.9864824356418235 1.0362628632424467 0.028902831125266704 0.12309822433825154 1527.7222989103575 3139579.2013946143 0.10629835172475398 0.02869599475799859 5.336393980638244e-09 8.272752114379962 0.04978042760062318 KLSVPT(ph)SDEEDEVPAPKPR ddPTM_PC-9_Lapatinib_30min_R1 1 KLSVPTSDEEDEVPAPKPR 19 2 Q5STZ8;Q8NE71-2;Q8NE71;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 KLS(0.002)VPT(0.499)S(0.499)DEEDEVPAPKPR 74.726 0.0020112000000000003 29971000.0 62315.0 55658.0 60248.0 50876.0 55042.0 66169.0 45564.0 52258.0 53581.0 46784.0 True False 61426.376672828555 55529.12732061736 55294.642004005436 54617.59075736078 51804.53777673559 63339.10611747272 47923.08097363576 54686.09745720834 47546.14354705643 54870.55206423848 1.1194780143803726 1.0120023442739898 1.0077289169474815 0.9953898530748961 0.9441227731058105 1.1543369573413418 0.8733843413408868 0.9966383679388866 0.8665147653588913 1.0 15.74374447069043 -7.289330214999996 24.995841448797215 0.9338542415665158 1.0299282388205644 0.343517247212079 0.0702671027051731 917.5938907396072 822346.3987353684 0.028246201271382082 0.019047634054609117 5.13652948004071e-08 7.289330214999996 0.09607399725404864 KLSVPTS(ph)DEEDEVPAPKPR ddPTM_PC-9_AZD4547_30min_R2 3 KLSVPTSDEEDEVPAPKPR 19 2 Q5STZ8;Q8NE71-2;Q8NE71;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 KLS(0.002)VPT(0.319)S(0.678)DEEDEVPAPKPR;KLS(0.005)VPT(0.165)S(0.83)DEEDEVPAPKPR;KLS(0.002)VPT(0.187)S(0.811)DEEDEVPAPKPR 85.176 0.00041891 117751000.0 171473.0 140152.0 211502.0 279880.0 255486.0 199864.0 190265.0 207306.0 176611.0 218131.0 True False 225997.8471400313 185453.39317826243 208697.34528704808 215357.9901028951 220016.1789093708 187366.47248490335 207198.2164078554 175271.62111796846 185946.29690149732 210494.300083909 1.0736530492746936 0.8810376010387713 0.9914631664793555 1.0231060414322255 1.045235803637752 0.8901261098766748 0.9843412212362059 0.8326668277863116 0.8833792498294436 1.0 17.68342164192319 -6.772877953646699 24.999170554575493 0.9117842576310425 0.9966163249932292 0.2903412615332174 0.06554940290012125 293.9754098979643 642483.414305275 0.022949818180692444 0.020411453384201535 1.68702705068759e-07 6.772877953646699 0.08483206736218663 KLSVPTS(ph)DEEDEVPAPKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLSVPTSDEEDEVPAPKPR 19 2 Q5STZ8;Q8NE71-2;Q8NE71;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 KLS(0.019)VPT(0.154)S(0.827)DEEDEVPAPKPR 71.637 0.0019730999999999998 15533000.0 45030.0 40892.0 42209.0 55739.0 48781.0 48135.0 51333.0 53450.0 51686.0 38601.0 True False 52652.68961695973 44951.487514186774 43215.4226385239 52616.1245382762 39222.71322733853 45610.71586317539 46470.36662126376 52046.994134956236 52441.80996969473 45599.05573465212 1.154688156775741 0.985798648458125 0.947726261920884 1.1538862744100993 0.8601650318283234 1.0002557098680098 1.0191080905640226 1.1414050860576075 1.150063507342381 1.0 15.476716328916666 -7.717745066694853 9.00075942914018 1.1092062712386912 1.0118766193021622 0.1326485187648928 0.09120832529915601 0.4919509772144965 94.96593336052736 0.04223877637897277 0.024174153885113927 1.9153799338902623e-08 7.717745066694853 -0.09732965193652898 KLSVPTS(ph)DEEDEVPAPKPR ddPTM_PC-9_Lapatinib_30min_R1 3 KLSVPTSDEEDEVPAPKPR 19 2 Q5STZ8;Q8NE71-2;Q8NE71;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 KLS(0.004)VPT(0.161)S(0.836)DEEDEVPAPKPR;KLS(0.006)VPT(0.183)S(0.811)DEEDEVPAPKPR;KLS(0.009)VPT(0.39)S(0.601)DEEDEVPAPKPR 79.347 0.00090042 116376000.0 175941.0 141600.0 166753.0 113848.0 150428.0 150173.0 111752.0 129585.0 147188.0 120278.0 True False 173432.04907637247 141272.13389987807 153043.21202519484 122220.76170579458 141580.12079282705 143750.45086036096 117537.97175326452 135605.9921733008 130610.13748164735 141067.89203963947 1.2294225607882396 1.0014478266973834 1.084890472327965 0.8663967394611034 1.003631079658039 1.0190160835462665 0.8332014468624572 0.9612817644939083 0.925867223173268 1.0 17.10603013305677 -1.5228791873119667 0.7582323861171457 0.9440822234299029 52.238453377719715 0.5872969012099395 0.06808563527970413 267.832105488516 1.1165044956545171 0.02436541443101598 23490.19597740671 0.029999969465552345 1.5228791873119667 51.29437115428981 KLT(ph)ATPTPLGGMTGFHMQTEDR ddPTM_PC-9_AZD4547_30min_R2 1 KLTATPTPLGGMTGFHMQTEDR 22 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 KLT(0.508)AT(0.405)PT(0.087)PLGGMT(0.001)GFHMQTEDR 51.526 0.0092689 4173000.0 21390.0 23584.0 31756.0 44008.0 34619.0 27296.0 22262.0 30689.0 19862.0 24362.0 True False 28191.575060360996 31207.066789743574 31334.89469099822 33862.63551682224 29812.749417437717 25589.176804967057 24243.274872791502 25946.72021306346 20911.864770923337 23509.09379521569 1.199177446222884 1.327446606899603 1.3328839879559777 1.4404058196285554 1.2681369038352672 1.0884799315477947 1.0312296630389566 1.1036886593367479 0.8895223675180151 1.0 14.520931308062044 -6.794360207301839 2.6725515729320155 1.0175680799049975 1.3291030447959422 0.8014820898289678 0.073584278071669 0.12154745422617876 1.777117219533885 0.028254454151217485 0.02568865678991639 1.6056089957093698e-07 6.794360207301839 0.3115349648909447 KLT(ph)ATPTPLGGMTGFHMQTEDR ddPTM_PC-9_Lapatinib_30min_R1 1 KLTATPTPLGGMTGFHMQTEDR 22 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 KLT(0.556)AT(0.413)PT(0.031)PLGGMTGFHMQTEDR 67.76 0.006381100000000001 3263000.0 25098.0 20613.0 22348.0 15580.0 16329.0 18750.0 18342.0 14630.0 23940.0 15298.0 True False 24740.097917590476 20565.271864958937 20510.63370577471 16725.805173356403 15368.560324049191 17948.1062083848 19291.65901190473 15309.76320944081 21243.62510062394 17942.23891669633 1.3788746227522548 1.1461931791478777 1.1431479538870892 0.9322027897974337 0.8565575564679291 1.0003270100078208 1.075209125320067 0.8532805343035622 1.1840007927246734 1.0 14.131072307291266 -4.84809928526838 1.2084336941767868 0.9831548886280806 1.513153479955168 0.5852992081252759 0.09958801464397743 0.9293261527415246 1.2579276731855453 0.030087927740843325 0.6038345975599659 1.418733144085449e-05 4.84809928526838 0.5299985913270874 KLTATEGPGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 KLTATEGPGSPR 12 1 Q8NC74 Q8NC74 RBBP8NL RBBP8 N-terminal-like protein 1 KLTAT(0.008)EGPGS(0.992)PR;KLTATEGPGS(1)PR 63.727 0.021238 28037000.0 57732.0 44828.0 71337.0 92426.0 78199.0 72696.0 62324.0 76070.0 64657.0 68971.0 True False 76089.5750998017 59317.774340681135 70391.02476923217 71118.61366746532 67342.4186629948 68150.30762799995 67870.715262414 64315.12941470027 68074.63702011837 66556.34628313864 1.1432354591117062 0.8912414465832641 1.0576155197850006 1.0685474434687001 1.0118106299963059 1.0239490512006235 1.0197482141475116 0.966326023082698 1.0228121106666634 1.0 16.022288616155265 -7.5442014331233995 23.12258080892216 0.9953488145552299 1.027587964364883 0.06379064640991194 0.06035263334662871 332.01649379168816 360032.20513685496 0.027024127277143095 0.015605697040978582 2.8562654518908184e-08 7.5442014331233995 0.032239149809653145 KLTATEGPGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 KLTATEGPGSPR 12 1 Q8NC74 Q8NC74 RBBP8NL RBBP8 N-terminal-like protein 1 KLTATEGPGS(0.999)PR;KLTATEGPGS(1)PR 100.68 0.0013556 39715000.0 118211.0 111093.0 111566.0 110143.0 105616.0 114173.0 100694.0 102464.0 103707.0 86986.0 True False 116525.2894627575 110835.77098403362 102393.47413721409 118243.28364627685 99403.87452904515 109290.08694026225 105907.442620474 107224.85150322251 92026.42557687571 102021.41419844053 1.1421650089667026 1.0863971241218868 1.0036468808210193 1.159004553850659 0.9743432328402737 1.0712465397478566 1.0380903210621528 1.051003383413808 0.902030483501006 1.0 16.638512478744765 -3.367926453924869 0.19990269502651087 0.9685197750941232 1.3677565329299985 0.35491247303228546 0.059044711169450884 30.669889185981 0.6997726132749565 0.1149959647024044 3.3162490404425586 0.00042862109956174596 3.367926453924869 0.3992367578358753 KLTS(ph)DEEGEPSGK ddPTM_PC-9_AZD4547_30min_R2 1 KLTSDEEGEPSGK 13 1 Q8WVC0-2;Q8WVC0 Q8WVC0-2 LEO1 RNA polymerase-associated protein LEO1 1 KLT(0.264)S(0.736)DEEGEPSGK 62.236999999999995 0.023035 23325000.0 43393.0 35835.0 47763.0 53177.0 57736.0 46377.0 44631.0 51587.0 47834.0 51656.0 True False 57191.0713695299 47417.96295838113 47129.63141221023 40917.86422646009 49720.35299590354 43477.038858585765 48603.072538296554 43615.41450132964 50362.40758495355 49847.53916286275 1.1473198542996121 0.9512598566492187 0.9454755882377157 0.8208602653938951 0.9974484965738496 0.8722003049445797 0.975034542417425 0.8749762823562582 1.0103288633849832 1.0 15.605234664009116 -4.7514356607257335 3.7976809421449107 0.930424038331326 1.1769778319673547 0.517257567383944 0.06034443645451289 0.21263602139066853 5.263835580576136 0.013988851774100874 0.15377622616293413 1.7724106023860866e-05 4.7514356607257335 0.2465537936360287 KLTS(ph)DEEGEPSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLTSDEEGEPSGK 13 1 Q8WVC0-2;Q8WVC0 Q8WVC0-2 LEO1 RNA polymerase-associated protein LEO1 1 KLT(0.228)S(0.772)DEEGEPSGK 105.0 0.00058559 12923000.0 73018.0 66491.0 58477.0 90752.0 84259.0 81053.0 77710.0 73448.0 73988.0 66862.0 True False 85378.50522876217 73091.78705628961 59871.313455257456 85667.45966195386 67749.05380829233 76802.43799434829 70348.74622832098 71520.06782458881 75069.93452845573 78983.55132069935 1.0809656415941236 0.9254051740407667 0.7580225560149875 1.0846240543694425 0.8577615551016282 0.9723852208481356 0.8906759072237939 0.9055058506320345 0.9504502301200279 1.0 16.269264616397813 KLTS(ph)DEEGEPSGK ddPTM_PC-9_Lapatinib_30min_R1 5 KLTSDEEGEPSGK 13 1 Q8WVC0-2;Q8WVC0 Q8WVC0-2 LEO1 RNA polymerase-associated protein LEO1 1 KLT(0.086)S(0.902)DEEGEPS(0.012)GK;KLT(0.005)S(0.994)DEEGEPS(0.001)GK;KLT(0.102)S(0.898)DEEGEPSGK;KLT(0.099)S(0.901)DEEGEPSGK;KLT(0.169)S(0.831)DEEGEPSGK 128.74 0.00032554 49341600.0 174309.0 150183.0 153993.0 149651.0 161439.0 167265.0 151133.0 157505.0 156955.0 136538.0 True False 171823.3216956442 149835.26049071585 141332.28997017047 160656.83376110138 151943.47542128604 160111.46586375925 158957.9272405518 164823.25730027165 139277.07509057783 160138.41137455084 1.0729675673737222 0.9356609648153887 0.8825633322888763 1.0032373393872254 0.9488259195097327 0.9998317361177728 0.9926283511628077 1.029254979398811 0.8697293416057437 1.0 17.28895987381452 -6.753709665424343 24.675445338725687 0.9810135351186386 0.9639570616310764 0.0023125990312926614 0.060532400459865916 917.3905519567215 2928571.092231302 0.020027833386328894 0.019653275253360334 1.7631543565723797e-07 6.753709665424343 -0.01705647348756223 KLVIIEGDLER ddPTM_PC-9_AZD4547_30min_R2 2 KLVIIEGDLER 11 1 A0A087WWU8;P06753-5;P06753-2;P06753-4;P06753-3;P06753-6;P06753-7;J3KN67;A0A494C0P6;A0A2R2Y2Q3;P06753 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 ; 80.245 0.010366 13885100.0 70936.0 75884.0 85757.0 100244.0 100812.0 86846.0 80847.0 102807.0 82538.0 84312.0 False True 93492.1724395404 100412.01900750095 84619.80614737154 77134.29455436114 86815.99394178734 81415.50589112578 88042.22637860799 86920.54041983814 86900.79017533333 81360.26254257545 1.1491134556088285 1.2341653759408138 1.0400630910340336 0.9480585748355608 1.0670564625618917 1.0006789966849163 1.0821281007117682 1.0683414446254156 1.068098694124279 1.0 16.31203671420529 -5.272679059249857 24.114365842995376 1.0353406910171017 1.1916394117930937 0.6750145425371799 0.04366333872002062 222.9928804505572 478424.94274680066 0.011521092990802858 0.024355242238443178 5.33729172114417e-06 5.272679059249857 0.15629872077599205 KLVIIEGDLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KLVIIEGDLER 11 1 A0A087WWU8;P06753-5;P06753-2;P06753-4;P06753-3;P06753-6;P06753-7;J3KN67;A0A494C0P6;A0A2R2Y2Q3;P06753 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 97.163 0.0034830999999999994 4288700.0 27165.0 25947.0 26317.0 25926.0 29519.0 23171.0 27881.0 27932.0 23914.0 18666.0 False True 31763.497966793482 28522.84668225094 26944.497087778294 24473.450273226066 23734.963853914553 21955.871969785756 25239.909839040294 27198.814596400345 24263.697009156822 22049.9980400253 1.4405215777859106 1.2935532524980764 1.2219727656604988 1.1099071405268017 1.0764156899619988 0.9957312436006259 1.1446672146285295 1.2335064405461116 1.1003945199955665 1.0 14.428490907094336 -5.089874795096898 1.2295006480317558 1.099860818817463 1.489515851594683 0.7421010686369565 0.06652722136594691 0.5043015983415351 0.9491941392067963 0.02244165040771772 0.21799170456537098 8.130648848738275e-06 5.089874795096898 0.3896550327772199 KLVIIEGDLER ddPTM_PC-9_Lapatinib_30min_R1 2 KLVIIEGDLER 11 1 A0A087WWU8;P06753-5;P06753-2;P06753-4;P06753-3;P06753-6;P06753-7;J3KN67;A0A494C0P6;A0A2R2Y2Q3;P06753 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 ; 83.226 0.008269799999999999 13457700.0 77861.0 75720.0 85472.0 68130.0 80453.0 90120.0 90077.0 76509.0 81896.0 68658.0 False True 76750.6878620414 75544.67499222301 78444.82209146106 73140.50747501766 75720.91271668379 86265.77767998076 94740.74630985412 80063.8874498363 72672.01007688802 80525.44381896545 0.9531234380351841 0.9381466454510945 0.974161934056744 0.9082906471083804 0.9403352421989373 1.0712859636504524 1.1765318117692964 0.9942681921733111 0.9024726425633463 1.0 16.297157086646592 -6.749383051283283 24.68350804455484 1.0377797374007365 0.9423762479336675 0.2904457431899037 0.06656808462400135 250.29140247705453 512432.76555655163 0.023726306928453712 0.023549066920476446 1.7808073878913935e-07 6.749383051283283 -0.095403489467069 KLYDIDVAK ddPTM_PC-9_Lapatinib_30min_R1 2 KLYDIDVAK 9 1 P62750;H7BY10;K7EJV9;K7ERT8;A8MUS3;K7EMA7 P62750 RPL23A 60S ribosomal protein L23a 0 ; 92.611 0.004362899999999999 11501700.0 271980.0 217070.0 222407.0 211221.0 216193.0 212127.0 220765.0 207019.0 217994.0 202902.0 False True 268101.5153249766 216567.38775174052 204121.55497584704 226754.89695260022 203476.95279179173 203054.82270218898 232195.13148855898 216637.8585000154 193441.22014141228 237973.34035007906 1.1266031519773452 0.9100489467986265 0.857749673453198 0.9528584026220098 0.855040957497423 0.8532671029598443 0.9757190916721182 0.9103450755505749 0.8128692897147377 1.0 17.860440434948828 -4.762588663702393 5.755650042550158 0.8990092947618402 1.1360671483399276 0.5820386870449596 0.05679980918749267 0.09492658053657124 11.027410846443857 0.013543684591889519 0.08926572119572172 1.727473270956843e-05 4.762588663702393 0.2370578535780874 KLYGDADYLEER ddPTM_PC-9_AZD4547_30min_R2 2 KLYGDADYLEER 12 1 B4E1E0;P17812-2;P17812;A0A3B3IRI2 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 0 ; 90.861 0.0042512 7960500.0 44037.0 40070.0 67886.0 93104.0 75598.0 66096.0 55466.0 71067.0 52048.0 59495.0 False True 58039.84997349779 53021.84388844236 66985.78728407554 71640.31124246091 65102.52261646651 61963.00667134756 60402.366548120306 60085.22810719741 54799.15102190203 57412.0981588686 1.0109341381827242 0.9235308513150365 1.1667538625520182 1.2478260425915901 1.133951287345696 1.0792674132878033 1.052084290335064 1.0465603946563984 0.9544878654367217 1.0 15.809067160260222 -7.8279633894489224 1.5732395703290407 0.9804640551342025 1.0971409207947007 0.21759273795310663 0.08321179841748665 0.7120847690963051 3.271721076648018 0.07723071087470923 0.028725165676476483 1.486060910320635e-08 7.8279633894489224 0.11667686566049817 KMANS(ph)SPVLSK ddPTM_PC-9_Lapatinib_30min_R1 1 KMANSSPVLSK 11 1 Q9NXE8 Q9NXE8 CWC25 Pre-mRNA-splicing factor CWC25 homolog 1 KMANS(0.675)S(0.324)PVLS(0.001)K 59.708999999999996 0.024822 7581000.0 97281.0 68349.0 67877.0 63360.0 66402.0 63154.0 52837.0 58768.0 66654.0 48856.0 True False 95893.75510084927 68190.74208985001 62296.41507279715 68019.70576276396 62496.36491135486 60453.05063916444 55572.64132657344 61498.575823131774 59146.72462226348 57300.69450347207 1.6735181995924797 1.190050882990922 1.087184293534564 1.1870659919949553 1.090673777218668 1.0550142744866968 0.9698423694185081 1.0732605661420969 1.0322165400400085 1.0 15.806265004581245 -2.0897960846460863 1.0303389498042785 1.053247400512245 199.99999999999753 0.9194284571129182 0.05432342577016496 142.82059657376817 0.6350191937131477 0.018166743775236905 66533.31838269862 0.008132122560837927 2.0897960846460863 198.94675259948528 KMANSSPVLS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 KMANSSPVLSK 11 1 Q9NXE8 Q9NXE8 CWC25 Pre-mRNA-splicing factor CWC25 homolog 1 KMANS(0.03)S(0.03)PVLS(0.941)K 55.31399999999999 0.03913 10745000.0 108590.0 60741.0 115590.0 199640.0 160080.0 105700.0 96313.0 108250.0 91672.0 104980.0 True False 143119.36118768563 80374.34039500581 114057.20107483582 153616.08240725315 137855.65518193555 99090.56229062927 104884.67041699628 91522.44983753537 96517.59476790282 101304.68215342515 1.4127615638824322 0.7933921580572111 1.1258828185463043 1.5163769249539996 1.3608024056889516 0.9781439533126157 1.035338823314694 0.90343751040969 0.9527456452775566 1.0 16.628341329359905 -6.78524095594612 22.933014538394023 0.971735478592311 1.2257387710756855 0.3408221558913257 0.18560593813342088 124.51561963286288 119969.9038189412 0.07052903137776455 0.06225266186260388 1.6396797910686946e-07 6.78524095594612 0.2540032924833745 KMDQFTDS(ph)SR ddPTM_PC-9_AZD4547_30min_R2 1 KMDQFTDSSR 10 1 A0A1B0GU26 A0A1B0GU26 1 KMDQFT(0.009)DS(0.495)S(0.495)R 63.816 0.01992 1933600.0 9809.3 7850.1 14163.0 19743.0 16089.0 17155.0 9584.7 18718.0 11740.0 12470.0 True False 12928.453353884945 10387.491307927661 13975.189366060195 15191.556376309338 13855.32006635534 16082.295138086522 10437.719731975776 15825.563196849753 12360.552432314971 12033.429095572597 1.0743781553208012 0.8632195549105351 1.1613638352846587 1.2624461619089686 1.151402476909351 1.3364681846177666 0.8673936289545328 1.3151332900338755 1.027184548489402 1.0 13.554760196978798 -5.282969326982262 23.74821114618729 1.153465028146902 0.9687988640672166 0.17477705588201298 0.14669677070723194 546.7456316555322 603077.2763537389 0.03603926079840851 0.07515941700407135 5.212315229455325e-06 5.282969326982262 -0.1846661640796855 KMDQFTDS(ph)SR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KMDQFTDSSR 10 1 A0A1B0GU26 A0A1B0GU26 1 KMDQFT(0.085)DS(0.457)S(0.457)R;KMDQFT(0.009)DS(0.495)S(0.495)R 63.816 0.01992 2422350.0 13423.300000000001 11847.2 16889.2 18665.8 18546.4 17491.3 17984.3 15675.699999999999 14630.800000000001 12827.400000000001 True False 15695.599567740075 13023.311720582848 17291.90258064768 17620.015741340103 14912.36605644639 16574.025436326152 16280.696908943442 15264.229484777057 14844.747771245771 15152.906078357477 1.035814482487799 0.8594596741534433 1.1411608104233733 1.1628142912141677 0.9841258158225739 1.0937852680284494 1.074427362299616 1.0073466703907432 0.9796634186526213 1.0 13.887306884981975 -10.519334678405368 14.790147518178898 1.0000164707526242 1.0393798021397274 0.017535614792549503 0.0835540951435079 0.0 0.0 0.08354044460194465 0.0202615339473458 3.024581709961814e-11 10.519334678405368 0.03936333138710313 KMDQFTDS(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 1 KMDQFTDSSR 10 1 A0A1B0GU26 A0A1B0GU26 1 KMDQFT(0.009)DS(0.495)S(0.495)R 63.816 0.01992 2442800.0 18429.0 12520.0 16089.0 14679.0 19164.0 14049.0 13633.0 15361.0 18441.0 12513.0 True False 18166.199080535313 12491.0107092265 14766.224525336014 15758.54262770853 18036.81119787364 13448.157019818555 14338.85003321869 16074.72813808751 16363.98038766108 14675.855377475544 1.237828979182824 0.8511265877147893 1.006157675006744 1.0737733660073192 1.2290126015793588 0.9163457034646678 0.9770367494371682 1.0953179712276908 1.115027367520701 1.0 13.841156972348374 -6.853165206262235 19.076192322360956 1.024006079458527 1.0635405893102428 0.05165691296430097 0.11577198353430544 16.904096597339148 3491.615255848338 0.042097799389638604 0.03712687037638413 1.4022801736416298e-07 6.853165206262235 0.03953450985171569 KMEES(ph)DEEAVQAK ddPTM_PC-9_AZD4547_30min_R2 1 KMEESDEEAVQAK 13 1 I3VM54;Q9Y2K7;Q9Y2K7-3;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 1 KMEES(1)DEEAVQAK 69.52199999999999 0.011287 14375000.0 107180.0 99930.0 124120.0 143640.0 131170.0 132200.0 116950.0 135690.0 115890.0 123220.0 True False 141261.01051750744 132230.41826234208 122474.08770143267 110526.01721587755 112959.30965901127 123933.5131014305 127358.32343782991 114722.2283460063 122015.7088058758 118906.10530524908 1.1880046878574495 1.112057433240182 1.0300067215810667 0.9295234835262779 0.9499874659003293 1.0422804849530252 1.0710831299274564 0.964813606933789 1.0261517564017753 1.0 16.85946326746381 -5.114285601975706 2.288931365276245 0.9984205686699325 1.1856730022868063 0.6963289010863677 0.0409347179835893 0.21109106829923918 1.9436274673935243 0.012168683381857323 0.05909842212215596 7.686248088086987e-06 5.114285601975706 0.18725243361687383 KMEES(ph)DEEAVQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KMEESDEEAVQAK 13 1 I3VM54;Q9Y2K7;Q9Y2K7-3;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 1 KMEES(1)DEEAVQAK;KMEES(1)DEEAVQAK 51.875 0.03574 21666800.0 94465.0 92311.0 84767.0 114492.0 113794.0 97637.0 99626.0 105635.0 95632.0 82837.0 True False 110456.05873120343 101475.02601785406 86788.16676063764 108077.38442807224 91496.88257706395 92516.74383988489 90188.70405022161 102862.19317953444 97030.43708203088 97854.69236266898 1.128776311736092 1.0369970368080808 0.8869085852212729 1.104468082404428 0.9350280540248216 0.9454502549249187 0.9216594715352464 1.05117282264101 0.9915767424051241 1.0 16.578353412680933 -4.900075847057071 3.910507369802336 0.9798838549327885 1.1273460590688096 0.3633038893414563 0.060600235676168214 0.243053164999301 6.433113941316143 0.014950225579195028 0.08049815289467802 1.2587055668410403e-05 4.900075847057071 0.14746220413602107 KMEES(ph)DEEAVQAK ddPTM_PC-9_Lapatinib_30min_R1 3 KMEESDEEAVQAK 13 1 I3VM54;Q9Y2K7;Q9Y2K7-3;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 1 KMEES(1)DEEAVQAK;KMEES(1)DEEAVQAK;KMEES(1)DEEAVQAK 79.013 0.0065796000000000006 28253500.0 220872.0 172552.0 199952.0 191636.0 187065.0 170390.0 171691.0 177899.0 186427.0 163141.0 True False 217722.32477703548 172152.46644556298 183512.71839704015 205729.55071895555 176062.2044839404 163102.81689848995 180580.319889485 186164.83699222934 165429.628096659 191339.70447828143 1.1378836680588094 0.8997216072584854 0.9590937693638504 1.0752057513620101 0.9201550977827755 0.8524253622279604 0.9437681550824297 0.972954554831355 0.8645859914319903 1.0 17.54577674963852 -4.753504779133616 24.978529782433977 0.9433541721450689 1.1378840250853923 0.4691764350437303 0.062154776221928235 271.957020079915 856065.798024722 0.015940052521698535 0.17008676732671607 1.7639863528255336e-05 4.753504779133616 0.19452985294032343 KMEVEELS(ph)PLALGR ddPTM_PC-9_AZD4547_30min_R2 2 KMEVEELSPLALGR 14 1 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4;P30305-3 G8JLH2 CDC25B M-phase inducer phosphatase 2 1 KMEVEELS(1)PLALGR;KMEVEELS(1)PLALGR 52.644 0.033025 12002800.0 47577.0 43404.0 79263.0 88037.0 74535.0 56066.0 45502.0 67027.0 45799.0 62410.0 True False 62705.49633692359 57433.4941885189 78211.92083047578 67741.42980809121 64187.10181775092 52560.1841569198 49551.58985094597 56669.51727723303 48219.84163948839 60225.04489612555 1.0411863776121089 0.953648009521264 1.298661063107109 1.1248049698415286 1.0657875295644694 0.872729679945845 0.8227738133929355 0.9409626406252583 0.8006609496540286 1.0 15.878075943503333 -6.704058418280674 4.35384988468359 0.8788545064446889 1.1058537926177534 0.5419445059022396 0.09646571029788299 0.16551407060205625 6.366022576662854 0.03392205849126174 0.03304897507572632 1.9767037297562266e-07 6.704058418280674 0.22699928617306453 KMPEHSTLMK ddPTM_PC-9_AZD4547_30min_R2 1 KMPEHSTLMK 10 1 A0A0D9SEP3;A0A0D9SFZ2;P49336-2;P49336 A0A0D9SEP3 CDK8 Cyclin-dependent kinase 8 0 68.016 0.014941 2865900.0 17463.0 16186.0 16449.0 23390.0 21511.0 19323.0 25087.0 24259.0 18115.0 23766.0 False True 23015.87074703525 21417.807965518532 16230.87551241432 17997.79687189765 18524.568956887902 18114.729755362623 27319.694400041346 20510.328966362747 19072.52191749453 22933.95957380739 1.0035716106049741 0.9338905432614245 0.707722339013426 0.7847662246885935 0.807735310480123 0.789864903051946 1.1912332151855212 0.8943213185823942 0.8316279557445909 1.0 14.48519783888754 KMPLDLS(ph)PLATPIIR ddPTM_PC-9_AZD4547_30min_R2 1 KMPLDLSPLATPIIR 15 1 B8ZZU6;E9PBF9;P15336-5;P15336;E9PEK8;H7C2N6;P15336-3;P15336-7;P15336-4;C9JCI8 B8ZZU6 ATF2 Cyclic AMP-dependent transcription factor ATF-2 1 KMPLDLS(1)PLATPIIR 98.292 0.00085045 11422000.0 50539.0 44049.0 69330.0 137250.0 113660.0 95688.0 63342.0 76746.0 69728.0 85963.0 True False 66609.3507234962 58286.97782485642 68410.63890058265 105609.13299136182 97880.27091441036 89704.61423335601 68979.3152902866 64886.66914763492 73413.67972746669 82953.46153510099 0.8029725281001212 0.7026467219839021 0.8246869706773517 1.2731130327415487 1.1799419711134445 1.0813848219630755 0.8315423372790615 0.7822056843303486 0.8849983878780318 1.0 16.340014563688122 -5.539351643623655 24.93676049799321 1.0027859350178716 0.7555238351925623 0.35159601686722963 0.14406520674114914 274.21959430624565 415113.51515957207 0.045334025053865024 0.07854647112856963 2.888340276909228e-06 5.539351643623655 -0.24726209982530933 KMPLDLS(ph)PLATPIIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KMPLDLSPLATPIIR 15 1 B8ZZU6;E9PBF9;P15336-5;P15336;E9PEK8;H7C2N6;P15336-3;P15336-7;P15336-4;C9JCI8 B8ZZU6 ATF2 Cyclic AMP-dependent transcription factor ATF-2 1 KMPLDLS(0.999)PLAT(0.001)PIIR;KMPLDLS(0.997)PLAT(0.003)PIIR 69.747 0.009352899999999999 30826000.0 72799.0 58021.0 79253.0 106806.0 103871.0 120007.0 109749.0 103571.0 108753.0 84595.0 True False 85122.43285420956 63780.94143256952 81142.69208867641 100822.00608972413 83518.22319421227 113713.62165975053 99352.78020604832 100852.37099254564 110343.30688453776 99931.40384634859 0.8518086365032073 0.6382472273744608 0.8119839106177161 1.0089121358161335 0.8357555280883203 1.1379167837429067 0.9942097917368403 1.0092159932788805 1.1041905010580877 1.0 16.60865050154935 -5.869217082284422 1.1744636545528937 1.0346870739346223 0.7294930829116723 0.6035163815617122 0.09087538914592976 0.3271101558924869 0.9033874912254815 0.032649966255095995 0.07557669860106361 1.351396898019217e-06 5.869217082284422 -0.3051939910229501 KMPLDLS(ph)PLATPIIR ddPTM_PC-9_Lapatinib_30min_R1 2 KMPLDLSPLATPIIR 15 1 B8ZZU6;E9PBF9;P15336-5;P15336;E9PEK8;H7C2N6;P15336-3;P15336-7;P15336-4;C9JCI8 B8ZZU6 ATF2 Cyclic AMP-dependent transcription factor ATF-2 1 KMPLDLS(1)PLATPIIR;KMPLDLS(0.998)PLAT(0.002)PIIR 65.423 0.012634000000000001 7812300.0 54179.0 31093.9 42004.1 30223.0 41468.8 44518.0 32915.8 34493.9 41468.7 31198.9 True False 53406.39752478822 31021.90398495353 38550.6850385149 32445.700240972463 39029.68671479768 42614.06891652665 34620.01906575369 36096.61252017297 36798.05832122989 36591.5882950789 1.4595266292928502 0.8477878504422717 1.0535395383124015 0.886698330209842 1.0666300243667388 1.16458647744071 0.9461196050462132 0.9864729628319385 1.0056425543621115 1.0 15.159224418230064 -4.749562804955849 24.999942221560442 0.9992649726952397 1.4595276625658524 0.7251681235245746 0.08570933557974925 291.70942124480274 614004.448900262 0.021265008626569704 0.3439429901143665 1.7800704675647385e-05 4.749562804955849 0.4602626898706127 KMPS(ph)KT(ph)S(ph)LK ddPTM_PC-9_AZD4547_30min_R2 1 KMPSKTSLK 9 2 Q14008-2;Q14008;Q14008-3 Q14008-2 CKAP5 Cytoskeleton-associated protein 5 3 KMPS(1)KT(1)S(1)LK 57.836000000000006 0.045624 0.0 524.74 0.0 0.0 798.06 1042.5 728.95 608.33 834.71 610.57 721.05 True False 691.5964047299589 0.0 0.0 614.0795969040888 897.7668698598695 683.3686412654137 662.4701915086365 705.7247492276132 642.8434836966401 695.8062589705393 0.9939496746597121 0.0 0.0 0.8825439394762461 1.2902540876653446 0.9821248838383154 0.9520900149544154 1.0142546723735262 0.9238828702802145 1.0 9.442541846233455 -5.888478961581162 6.090534139901583 1.026858597428091 0.3029213931197222 0.5630440275272706 0.2743203270516349 0.14378853119877213 7.153140832014368 0.0772553444953647 0.11586240089418394 1.2927693245905935e-06 5.888478961581162 -0.7239372043083688 KMS(ph)GGSTMSSGGGNTNNSNSK ddPTM_PC-9_AZD4547_30min_R2 3 KMSGGSTMSSGGGNTNNSNSK 21 1 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 KMS(0.863)GGS(0.087)T(0.043)MS(0.003)S(0.003)GGGNTNNSNSK;KMS(0.801)GGS(0.189)T(0.01)MSSGGGNTNNSNSK;KMS(0.544)GGS(0.106)T(0.35)MSSGGGNTNNSNSK 117.83 1.2522e-06 21988100.0 72851.0 75505.0 86489.0 116972.0 120929.0 96175.0 93878.0 113546.0 87085.0 87245.0 True False 96016.10260506577 99910.51466924994 85342.0993490913 90005.91259938492 104140.09573648346 90161.16204636979 102232.96013421637 96000.07472750843 91688.13531244895 84190.57910531125 1.1404613630815197 1.1867184634075878 1.0136775427371707 1.0690734468853036 1.2369566386545223 1.0709174708679714 1.2143040375852088 1.1402709869405347 1.0890545745950893 1.0 16.3613711848309 -8.612002961665725 3.1339523003251344 1.0001495555919966 1.1332698159657046 0.28208329640801 0.06528552623840199 0.5077325029561758 11.817733388495919 0.06325855244854275 0.016791024477506983 2.443413889807045e-09 8.612002961665725 0.13312026037370805 KMS(ph)GGSTMSSGGGNTNNSNSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KMSGGSTMSSGGGNTNNSNSK 21 1 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 KMS(0.33)GGS(0.33)T(0.33)MS(0.006)S(0.005)GGGNTNNSNSK 65.423 0.0014121 13157000.0 8123.2 7000.7 8562.1 9364.0 11390.0 9397.1 10587.0 9870.0 8917.6 5637.9 True False 9498.297319486728 7695.683229985507 8766.252935945076 8839.365438497605 9158.211263799138 8904.299533350899 9584.122716757622 9610.922958129428 9048.003029558291 6660.006640408154 1.426169346717743 1.1555068403826518 1.316252882205511 1.327230724496078 1.3751054253059847 1.336980578866991 1.4390560301558895 1.4430800864097078 1.3585576588860262 1.0 12.701307900408946 -4.4592985235885445 22.88314731090427 1.3257262393464124 4.2892710955377 0.05409128424793597 0.1286167438292715 1687.0363334282313 615318.8341390645 0.02981471478864493 3410.4057673418415 3.4729735552302734e-05 4.4592985235885445 2.9635448561912874 KMS(ph)GGSTMSSGGGNTNNSNSK ddPTM_PC-9_Lapatinib_30min_R1 5 KMSGGSTMSSGGGNTNNSNSK 21 1 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 KMS(0.994)GGS(0.002)T(0.004)MSSGGGNTNNSNSK;KMS(0.697)GGS(0.151)T(0.151)MSSGGGNTNNSNSK;KMS(0.596)GGS(0.036)T(0.345)MS(0.008)S(0.012)GGGNT(0.003)NNSNSK;KMS(0.567)GGS(0.208)T(0.208)MS(0.015)S(0.001)GGGNTNNSNSK;KMS(0.351)GGS(0.312)T(0.312)MS(0.023)S(0.001)GGGNTNNSNSK 108.45 2.0405e-05 25292900.0 99393.7 73377.79999999999 91632.0 77011.40000000001 91942.90000000001 83222.0 81009.59999999999 80777.0 88703.8 68886.7 True False 97976.32761142767 73207.89821241851 84098.37066974874 82675.07525849956 86534.99938869642 79662.78905995739 85203.8807049829 84530.19431093641 78713.04395157586 80793.67430924195 1.2126732500915631 0.9061092819248635 1.040902909649311 1.0232864882720454 1.0710615667444365 0.986002799613296 1.0545860357688481 1.0462476800769418 0.9742476081765713 1.0 16.301954722032256 KMS(ph)IQDSLALQPK ddPTM_PC-9_AZD4547_30min_R2 1 KMSIQDSLALQPK 13 1 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 KMS(0.655)IQDS(0.345)LALQPK 81.311 0.017301 4932200.0 20207.0 21070.0 24063.0 27163.0 34030.0 23868.0 26340.0 32349.0 30256.0 28403.0 True False 26632.4056682896 27880.465453693057 23743.908897515106 20900.990014166553 29305.52190055766 22375.53018687549 28684.208972658704 27350.205356068625 31855.270391151786 27408.619615200354 0.9716799328894229 1.0172152353937236 0.8662934956544524 0.7625699618442375 1.0692082385756236 0.8163683724687252 1.0465397154386764 0.9978687631864783 1.1622354879005068 1.0 14.742342050856056 -7.373441417381545 9.248963763515214 1.0523826986855795 0.9193981295126866 0.3238091789442763 0.09516733104291958 0.4551384524095814 34.69547186373092 0.03973194623830584 0.026740941791776426 4.2321259363278606e-08 7.373441417381545 -0.13298456917289292 KMS(ph)IQDSLALQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KMSIQDSLALQPK 13 1 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 KMS(0.999)IQDS(0.001)LALQPK;KMS(0.996)IQDS(0.004)LALQPK 58.751999999999995 0.023878 44113000.0 478000.0 450090.0 386140.0 458670.0 572210.0 420520.0 352730.0 596190.0 391370.0 330690.0 True False 558915.9590696589 494771.9606588179 395347.04204410495 432972.2069282035 460089.5581438537 398467.19091684866 319316.86085594835 580540.6442155198 397093.04585070314 390641.4792594011 1.4307644956938048 1.2665627869237872 1.012045732556678 1.108362091370981 1.1777795819740289 1.020032976713799 0.8174166795121866 1.4861213543327239 1.0165153137437768 1.0 18.575485620652415 -4.993884023258249 3.2916687166555127 1.0906465130031058 1.4233897408555567 0.3234256926483654 0.1628649573821667 0.3029692170428366 6.527536434967967 0.04176905115787149 0.19796296897531276 1.0141821831938125e-05 4.993884023258249 0.3327432278524509 KMS(ph)PTGNEMK ddPTM_PC-9_AZD4547_30min_R2 2 KMSPTGNEMK 10 1 O95171-2;O95171;O95171-3;F2Z2X8 O95171-2 SCEL Sciellin 1 KMS(0.996)PT(0.004)GNEMK;KMS(0.963)PT(0.037)GNEMK 86.803 0.0050577 35721000.0 136713.0 127130.0 132218.0 172887.0 158048.0 137546.0 138432.0 162676.0 140517.0 161440.0 True False 180184.89019294665 168222.28633735154 130464.70293029361 133030.57322752324 136105.76330706233 128945.22687631888 150752.17982168187 137538.16212259492 147944.441748859 155788.03473851163 1.156602883497342 1.07981519004146 0.8374500849778166 0.8539203504994044 0.8736599286043645 0.8276966013002982 0.9676749570319545 0.8828544653859399 0.9496521475296996 1.0 17.249224906255485 -5.124061660150825 4.235627147279608 0.8927274060433482 1.1407717049479253 0.7204414166906496 0.0552122379811796 0.10638321079234905 3.081566718797626 0.014051193667471411 0.042766768480096744 7.515161878704113e-06 5.124061660150825 0.24804429890457713 KMS(ph)PTGNEMK ddPTM_PC-9_Lapatinib_30min_R1 2 KMSPTGNEMK 10 1 O95171-2;O95171;O95171-3;F2Z2X8 O95171-2 SCEL Sciellin 1 KMS(0.994)PT(0.006)GNEMK;KMS(0.971)PT(0.029)GNEMK 78.529 0.0092929 32148800.0 157673.0 132164.0 108679.0 132117.0 127027.0 116988.0 108678.0 125040.0 112471.0 96244.0 True False 155424.55410631275 131857.9823781319 99743.83213307173 141833.32490939245 119555.5216046909 111984.69595234789 114304.8150744619 130849.81488096257 99803.33160786451 112879.64716293091 1.3769050312672608 1.168128938140705 0.8836299070735144 1.2565004274390554 1.0591415247083826 0.9920716335222838 1.012625552500832 1.1591975893767055 0.8841570125020679 1.0 16.784425857942765 -4.888482978460558 3.571515104713667 1.042461626433658 1.3824762133523802 0.4910417659676468 0.10804372232071874 0.20707789647947167 4.541806209692572 0.026265549856126037 0.1581082077696242 1.2927573675553002e-05 4.888482978460558 0.34001458691872233 KMSEMEEEMK ddPTM_PC-9_AZD4547_30min_R2 2 KMSEMEEEMK 10 1 O60237;O60237-6;E1CKY7;O60237-4;O60237-3 O60237 PPP1R12B;sm-M20 Protein phosphatase 1 regulatory subunit 12B 0 ; 54.066 0.034035 21187300.0 132828.0 150571.0 115294.0 96670.0 93825.0 92713.0 156831.0 108012.0 106694.0 92646.0 False True 175064.54100596672 199240.13117361252 113765.12622823856 74384.22503661155 80799.01828738842 86915.64145365308 170788.6551780953 91321.22726883952 112333.62701988182 89402.49173924775 1.9581617648483647 2.2285746996260283 1.2725050948249532 0.8320151216093771 0.9037669612503384 0.9721836580030918 1.910334397347887 1.0214617679246343 1.256493245708579 1.0 16.448027420910613 -5.319959716925274 5.2795902832722925 1.1416630840059414 2.093737917269814 0.6253174984300657 0.29413323479272563 0.12647472586102898 7.477634925062181 0.08138252690174953 0.17837364411413337 4.7867448981512024e-06 5.319959716925274 0.9520748332638724 KMSGGS(ph)TMSSGGGNTNNSNSK ddPTM_PC-9_AZD4547_30min_R2 3 KMSGGSTMSSGGGNTNNSNSK 21 1 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 KMS(0.133)GGS(0.394)T(0.394)MS(0.07)S(0.007)GGGNTNNSNSK;KMS(0.032)GGS(0.474)T(0.474)MS(0.019)S(0.002)GGGNTNNSNSK;KMS(0.267)GGS(0.335)T(0.335)MS(0.058)S(0.004)GGGNTNNSNSK 69.765 0.00096438 18562600.0 57163.8 53614.4 74349.6 99785.0 89297.0 94801.5 69771.7 91815.0 75847.7 74778.5 True False 75340.69931909606 70944.20631326432 73363.6757248344 76781.1099128818 76899.652928419 88873.54721849642 75981.24613430741 77627.1014488065 79856.85457585151 72160.52747580399 1.044070795413163 0.9831442312703783 1.016673218601871 1.0640319936495355 1.0656747617900115 1.2316088910006435 1.0529474879432463 1.0757557374401885 1.1066556380512624 1.0 16.138922263929125 -5.968212349533276 2.2604361141612226 1.0976195288710213 1.0105786715881522 0.24418726567212434 0.057303629715432854 0.3872764956474815 3.991936152983744 0.01785989512163294 0.028341451156517785 1.0759390015313038e-06 5.968212349533276 -0.08704085728286914 KMSGGS(ph)TMSSGGGNTNNSNSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KMSGGSTMSSGGGNTNNSNSK 21 1 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 KMS(0.05)GGS(0.323)T(0.323)MS(0.271)S(0.033)GGGNTNNSNSK;KMS(0.012)GGS(0.487)T(0.487)MS(0.012)S(0.002)GGGNTNNSNSK;KMS(0.087)GGS(0.404)T(0.404)MS(0.087)S(0.019)GGGNTNNSNSK 87.156 0.00014606 17382100.0 32455.8 33165.6 34029.7 39995.6 44605.4 41152.5 41943.4 39909.9 36314.3 34211.0 True False 37949.9259087302 36458.061584185496 34841.09710635593 37754.7761994847 35865.29207254311 38994.390455164124 37970.21750808085 38862.30741303443 36845.327937594026 40413.18348587303 0.9390481678335513 0.9021328794087677 0.8621220626812313 0.9342193052591957 0.8874651531740949 0.9648928169391836 0.9395502712958471 0.9616245012378021 0.9117155531801597 1.0 15.302538381612314 -6.764249165447496 24.999311887849483 0.9521577659822634 0.9040798290971122 0.4265909325846211 0.02916619526809598 75.19184501286877 668995.2651123315 0.009672185798897195 0.008908853762522068 1.7208809798798408e-07 6.764249165447496 -0.04807793688515127 KMSGGS(ph)TMSSGGGNTNNSNSK ddPTM_PC-9_Lapatinib_30min_R1 1 KMSGGSTMSSGGGNTNNSNSK 21 1 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 KMS(0.076)GGS(0.452)T(0.452)MS(0.019)S(0.001)GGGNTNNSNSK 81.016 0.00026355 5172300.0 11375.0 8800.6 7548.6 6768.6 7645.6 7056.9 7044.1 10433.0 8482.1 6032.5 True False 11212.790414080479 8780.222751407251 6927.983246438651 7266.385423387691 7195.900839827943 6755.0928374373725 7408.809030953995 10917.755267539034 7526.7565775272515 7075.209587199018 1.5847997541115209 1.2409841211337493 0.9791912396451492 1.0270205191567134 1.017058328964175 0.9547551566047141 1.0471504680735606 1.5430999086291703 1.0638210055494617 1.0 12.788557169841107 -4.832269748418056 3.061970212737601 1.0891163368140855 1.63428501544487 0.47755784821598257 0.16037036370967178 0.30836934045380937 4.549990152480281 0.04400248512423786 0.3883001994494466 1.471398305567192e-05 4.832269748418056 0.5451686786307846 KMSGGST(ph)MSSGGGNTNNSNSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KMSGGSTMSSGGGNTNNSNSK 21 1 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 KMS(0.166)GGS(0.22)T(0.599)MS(0.011)S(0.002)GGGNT(0.001)NNSNSK;KMS(0.046)GGS(0.319)T(0.507)MS(0.109)S(0.019)GGGNTNNSNSK 68.88 0.00077909 24713000.0 66907.0 61027.6 69044.0 80925.0 94354.0 80379.0 79761.0 70763.0 72329.0 68862.0 True False 78233.03362651398 67086.01681064232 70690.270810828 76391.03461239007 75866.0110258562 76163.78374085756 72205.46066036707 68905.54622959612 73386.67479197553 81346.13548870807 0.9617301812373591 0.8246982651063339 0.8690058892919476 0.9390862166155903 0.9326320244971862 0.9362925882499988 0.8876323408183312 0.847066007692045 0.9021531797556945 1.0 16.31178618895423 -6.830222645867506 0.008065388341872815 1.8082967973891821 4.993131169771856e-07 0.13687806776581757 0.04764915312969807 9274.115186058247 30.83747939266629 3384.5810772692566 3527.152164757389 1.4783503012381028e-07 6.830222645867506 -1.808296298076065 KMSGGST(ph)MSSGGGNTNNSNSK ddPTM_PC-9_Lapatinib_30min_R1 1 KMSGGSTMSSGGGNTNNSNSK 21 1 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 KMS(0.331)GGS(0.289)T(0.371)MS(0.008)SGGGNTNNSNSK 73.21300000000001 0.0008592000000000001 5959500.0 16664.0 10960.0 14066.0 11263.0 12783.0 13101.0 14254.0 11530.0 11731.0 9540.2 True False 16426.368304196665 10934.622793380393 12909.547776330177 12091.318592266573 12031.129072344964 12540.700769922627 14992.002374642352 12065.725892334427 10409.731247093536 11189.21085848256 1.4680542275904835 0.977247004429346 1.1537496200228836 1.0806229988149811 1.0752437526212266 1.1207850963337151 1.3398623517115051 1.0783357329607726 0.9303364981456133 1.0 13.44982067049289 -4.7497407600875645 24.972350249459936 1.0974109013026814 1.468055063509444 0.53170624603069 0.10746270997889258 446.894589731398 953899.292721525 0.027261916016329105 0.43267388667203305 1.7793412209436202e-05 4.7497407600875645 0.37064416220676266 KMTVS(ph)TDNLLVNK ddPTM_PC-9_Lapatinib_30min_R1 1 KMTVSTDNLLVNK 13 1 Q86YC2 Q86YC2 PALB2 Partner and localizer of BRCA2 1 KMT(0.245)VS(0.377)T(0.377)DNLLVNK 89.959 0.0056251999999999995 2691000.0 7074.6 9704.8 11354.0 9280.0 13657.0 12220.0 9922.5 11000.0 10919.0 9676.6 True False 6973.71490667725 9682.32913186114 10420.517947707442 9962.482157172497 12853.722110695071 11697.379086211318 10436.238498834626 11511.10015747429 9689.187237832615 11349.187416740982 0.6144682126220287 0.8531297242989317 0.9181730431498842 0.8778145774980347 1.1325676137601515 1.0306798766012732 0.9195582129025659 1.01426646109434 0.8537340059729976 1.0 13.470301386157725 -4.288567692047321 1.0004635410832308 0.9825873284169829 1.3828968140295433e-12 0.6773348188532581 0.07550740525736253 2.676142589765252 1.0928045025358948 0.024871293152316405 3.578914983321593 5.145555986803279e-05 4.288567692047321 -0.9825873284156 KNES(ph)PFWK ddPTM_PC-9_AZD4547_30min_R2 1 KNESPFWK 8 1 P46013 P46013 MKI67 Antigen KI-67 1 KNES(1)PFWK 63.408 0.026650999999999998 8379300.0 42659.0 46787.0 50582.0 62692.0 59312.0 64433.0 51564.0 62506.0 53393.0 46302.0 True False 56223.67463767833 61909.98278034822 49911.249630308346 48239.327981744675 51077.55259964369 60403.99432423952 56153.096107295874 52847.13394498825 56215.24497603008 44680.98107323196 1.2583357233255004 1.3856003447837903 1.1170580509077004 1.0796389609861206 1.14316094617367 1.3518949869349914 1.2567561131941387 1.182765746758604 1.2581470600185234 1.0 15.447373243390984 -10.912586405415173 3.2922847874544354 0.9978279132176283 1.2240279101706115 0.34697091103335953 0.09295196109713184 36755734.63202202 61935543.396798626 800828.1298863537 0.025095016742782653 1.2229637790811471e-11 10.912586405415173 0.2261999969529832 KNES(ph)PFWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KNESPFWK 8 1 P46013 P46013 MKI67 Antigen KI-67 1 KNES(1)PFWK 58.511 0.035469 5345600.0 52458.0 53618.0 53875.0 66940.0 62257.0 49747.0 56610.0 48659.0 54356.0 48030.0 True False 61338.10330727232 58940.840690982775 55159.58432207531 63189.56882240808 50058.187765613926 47138.17974541156 51247.490979092225 47381.75280847213 55150.85366855094 56737.45879472923 1.0810865451198262 1.0388346948041005 0.972189898769303 1.1137186995107056 0.8822775786754871 0.8308123195286741 0.9032390957885655 0.8351053045906556 0.9720360206487485 1.0 15.792013914963574 -6.275645825588217 24.936079292733893 0.8919783746470347 1.0448938643452756 0.5829494191857111 0.060534282002274134 507.1535187862464 890186.9265414176 0.01799697967978353 0.02050511914738993 5.300955694654622e-07 6.275645825588217 0.15291548969824098 KNES(ph)PFWK ddPTM_PC-9_Lapatinib_30min_R1 1 KNESPFWK 8 1 P46013 P46013 MKI67 Antigen KI-67 1 KNES(1)PFWK 55.353 0.041157 5435700.0 75235.0 66458.0 69819.0 55192.0 59446.0 53841.0 42550.0 43247.0 46772.0 33692.0 True False 74162.13510359074 66304.12058416729 64078.751329133884 59251.00379511474 55949.50315533271 51538.345939501116 44753.03080125101 45256.413500935545 41504.04482900513 39515.617308231944 1.8767803758475308 1.6779219230457203 1.6216057269029407 1.4994325745424075 1.415883313144579 1.3042525829088991 1.1325403435347068 1.145279172736286 1.0503200419536138 1.0 15.270135325502823 -5.94161131571576 0.38461987723777125 0.972503537672748 2.065244535953132 0.9842126235065036 0.03518257237285401 0.2789372207786351 0.06174885194984713 0.03471045819690038 0.13028272830130594 1.143901644337912e-06 5.94161131571576 1.092740998280384 KNGNGGPGPYVGQAGTAT(ph)LPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KNGNGGPGPYVGQAGTATLPR 21 1 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 KNGNGGPGPYVGQAGT(0.101)AT(0.899)LPR 108.49 4.6187e-05 6220500.0 27694.0 26006.0 25031.0 28219.0 24231.0 25743.0 25430.0 25169.0 23131.0 24422.0 True False 32382.04721856723 28587.70381233349 25627.833970596115 26637.980917232373 19483.109493688913 24392.991762038524 23021.086302743603 24508.34041875984 23469.247115447288 28849.51527555439 1.1224468386824553 0.9909249267892294 0.8883280611758436 0.9233424084530127 0.6753357658732626 0.845525185745769 0.7979713379188211 0.8495234732601196 0.8135057692055552 1.0 14.816259458717306 -4.916432330487037 1.1288981447660769 0.8266489275018339 1.2193746836693595 0.5590894304880476 0.07897121661140218 0.9115026824449365 1.1383937193035694 0.024042652075980143 0.4036319555424084 1.2121815499009234e-05 4.916432330487037 0.3927257561675256 KNGNGGPGPYVGQAGTAT(ph)LPR ddPTM_PC-9_Lapatinib_30min_R1 1 KNGNGGPGPYVGQAGTATLPR 21 1 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 KNGNGGPGPYVGQAGT(0.031)AT(0.969)LPR 130.57 2.1615999999999998e-05 5246500.0 70130.0 38541.0 24543.0 29577.0 18450.0 22440.0 17059.0 14963.0 23980.0 12357.0 True False 69129.93333973298 38451.76068245198 22525.16927871973 31752.191245979626 17364.807274095638 21480.293510194922 17942.23154967195 15658.235605117085 21279.119879405276 14492.890985332479 4.769920191195523 2.653146340600165 1.554221949334768 2.1908804308342904 1.1981603457632906 1.482126204629155 1.238002243157033 1.0804080166589256 1.4682453556671886 1.0 13.823057786327405 -2.19107213997464 0.7507218615072877 1.280904668529897 199.99999999999997 0.9340810835581553 0.27852131225628807 27.097556923809506 0.3563784293187529 0.10179673364556316 8797.430392413024 0.0064406227245616034 2.19107213997464 198.71909533147007 up KNGSTAVAESVAS(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 5 KNGSTAVAESVASPQK 16 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 KNGSTAVAESVAS(1)PQK;KNGSTAVAESVAS(1)PQK;KNGSTAVAESVAS(1)PQK;KNGSTAVAESVAS(1)PQK;KNGSTAVAES(0.001)VAS(0.999)PQK 182.77 2.9445e-07 332458000.0 284624.0 263044.0 320960.0 394205.0 405149.0 374938.0 360565.0 373669.0 338595.0 349895.0 True False 375128.5114530244 348067.8288942208 316703.8606884616 303327.12765653763 348901.054730797 351493.0675886849 392654.5864930411 315927.0421093952 356492.44044460723 337645.28254974924 1.1110136312884877 1.0308683310063302 0.9379780410283027 0.8983603305988582 1.0333360860132537 1.041012819531679 1.1629203983775094 0.9356773467221358 1.055819402399265 1.0 18.36514887530965 -6.494866121828481 24.7450331618107 1.042179834454526 0.9897002378108982 0.0743310033778859 0.07437574703224045 1650.533741927344 1458004.4518309846 0.024168348907558368 0.02734446257762458 3.1998813719215574e-07 6.494866121828481 -0.05247959664362789 KNGSTAVAESVAS(ph)PQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 KNGSTAVAESVASPQK 16 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 KNGSTAVAES(0.002)VAS(0.998)PQK;KNGSTAVAES(0.003)VAS(0.997)PQK;KNGSTAVAESVAS(1)PQK;KNGSTAVAES(0.002)VAS(0.998)PQK;KNGSTAVAESVAS(1)PQK;KNGSTAVAESVAS(1)PQK;KNGSTAVAESVAS(1)PQK;KNGSTAVAESVAS(1)PQK 162.09 1.4035999999999999e-05 311300100.0 1031925.0 985609.0 1028920.0 1196120.0 1218665.0 1181668.0 1233300.0 1054773.0 1070761.0 997922.0 True False 1206609.5210522108 1083453.74785704 1053453.3550008307 1129105.2742733594 979876.3415098995 1119699.249872373 1116472.8956812283 1027086.3263743728 1086418.853944208 1178837.3590537955 1.0235589428729226 0.9190867082179038 0.8936375717226969 0.9578125986604684 0.8312226737506913 0.9498335298527608 0.9470966347532245 0.8712705942733042 0.9216019882642946 1.0 20.168933256706993 -4.539239704094909 0.0008306268530728744 1.688659638768139 0.15889819313591708 0.0 0.054779111068296686 6726510.427235419 929.8476147881014 852164.3191534475 860356.4154116863 2.8890848434058113e-05 4.539239704094909 -1.529761445632222 KNGSTAVAESVAS(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 4 KNGSTAVAESVASPQK 16 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 KNGSTAVAESVAS(1)PQK;KNGSTAVAESVAS(1)PQK;KNGSTAVAESVAS(1)PQK;KNGSTAVAESVAS(1)PQK 180.04 1.7431999999999999e-06 317230000.0 419481.0 288542.0 269726.0 272940.0 292624.0 290497.0 243097.0 256204.0 286537.0 219139.0 True False 413499.12401660695 287873.8987269679 247550.16945246916 293012.9181011492 275412.4316409196 278073.1204915817 255683.37317724392 268108.1731586865 254264.18569162427 257016.88416563658 1.6088403116354182 1.1200583170304301 0.9631669540158827 1.1400531877598932 1.0715733035788724 1.0819254983745552 0.9948115821545277 1.0431539314199376 0.9892898146246364 1.0 17.971503611684447 -4.767054242063843 3.8149616700145 1.041919123778454 1.674708134859534 0.9205179222063767 0.05022071454392273 0.06535134557046858 1.6890227176043582 0.012555864260559997 0.11916748228559074 1.709801752699779e-05 4.767054242063843 0.6327890110810801 KNLS(ph)CTNVLQSNS(ph)T(ph)KKCGIDT(ph)IDLK ddPTM_PC-9_Lapatinib_30min_R1 1 KNLSCTNVLQSNSTKKCGIDTIDLK 25 3 Q6ZU52-2;Q6ZU52 Q6ZU52-2 KIAA0408 Uncharacterized protein KIAA0408 4 KNLS(0.498)CT(0.498)NVLQS(0.088)NS(0.963)T(0.963)KKCGIDT(0.992)IDLK 45.395 0.018614 10211000.0 59985.0 48796.0 57434.0 50785.0 59853.0 44273.0 41177.0 45945.0 60473.0 45454.0 True False 59129.60290009827 48683.015860017316 52711.99822165131 54519.898313793696 56332.56421552551 42379.546995403754 43308.943579391635 48079.77243046876 53661.89393107902 53310.663336352074 1.10915151302907 0.9131947121509703 0.9887702557568339 1.02268279743233 1.0566847360369052 0.7949544114283327 0.8123880077451531 0.9018790880000846 1.0065883741215325 1.0 15.702136512980504 -6.745741565128777 24.999286123121685 0.8913560252908204 1.0108944382031941 0.3385790759334394 0.07914978599819995 281.95709295112897 449025.17027988855 0.02676018723099323 0.026671459114104335 1.7958019337147163e-07 6.745741565128777 0.11953841291237377 KNPALCFLYDQS(ph)NSK ddPTM_PC-9_AZD4547_30min_R2 1 KNPALCFLYDQSNSK 15 1 P60608 P60608 ERVFC1-1 Endogenous retrovirus group FC1 member 1 Env polyprotein;Surface protein;Truncated transmembrane protein 1 KNPALCFLY(0.002)DQS(0.499)NS(0.499)K 50.387 0.045239 7532500.0 10669.0 8382.9 14389.0 80097.0 43556.0 26174.0 17063.0 21697.0 14438.0 29824.0 True False 14061.520071014087 11092.508488455782 14198.192458394422 61631.874136314094 37509.001231286755 24537.335642336162 18581.573944589054 18344.22719745962 15201.163204238812 28779.87083771909 0.4885887136291441 0.38542593019277444 0.49333760177221425 2.1414923813882774 1.3033067953219306 0.8525867187067903 0.6456447997756793 0.6373978292292248 0.5281873323877488 1.0 14.812772496916045 -7.005025258447397 24.015233361739302 0.6835227339316028 0.9806301644042208 0.05729165791736124 0.4912634118175955 434.6346521275183 2077089.9642506365 0.1975501904962289 0.16929341904727835 9.884956023532361e-08 7.005025258447397 0.297107430472618 KNPDLGFSDY(ph)AAAQLR ddPTM_PC-9_Lapatinib_30min_R1 1 KNPDLGFSDYAAAQLR 16 1 O95926-2;O95926 O95926-2 SYF2 Pre-mRNA-splicing factor SYF2 1 KNPDLGFSDY(1)AAAQLR 61.409 0.045125 0.0 26726.0 10994.0 18226.0 11129.0 11832.0 14859.0 9620.6 9053.3 13608.0 7333.0 True False 26344.88233905185 10968.54406846935 16727.52863439457 11947.463785255679 11136.065022607021 14223.515208020783 10118.707594042668 9473.949368696552 12075.323741407283 8600.49927939169 3.063180576292684 1.2753380602858617 1.9449485536818394 1.389159326352588 1.294816110186881 1.653801104559456 1.1765256022157773 1.10155806784355 1.4040259000244188 1.0 13.070204698778475 -3.165866702617734 1.5219958433132337 1.3556792609871153 199.9999999914751 0.7658222352793232 0.2772914680343133 77.82214279234773 1.9881613421542546 0.07612521677080397 52540.437453750106 0.0006825481555213349 3.165866702617734 198.644320730488 up KNQKPSQVNGAPGS(ph)PTEPAGQK ddPTM_PC-9_AZD4547_30min_R2 2 KNQKPSQVNGAPGSPTEPAGQK 22 2 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 KNQKPS(0.001)QVNGAPGS(0.5)PT(0.5)EPAGQK;KNQKPSQVNGAPGS(0.992)PT(0.008)EPAGQK 99.40899999999999 3.4673000000000005e-05 102977000.0 317516.0 307708.0 370190.0 451970.0 410430.0 339010.0 361200.0 384170.0 317225.0 398650.0 True False 418479.48325692257 407168.59344209684 365281.03872215084 347775.2993668912 353448.87903749273 317811.65110828925 393346.1002628822 324805.3538483691 333992.8658723267 384693.3848396172 1.0878260447119235 1.0584236940072411 0.9495381337904744 0.9040324400480203 0.9187807562244653 0.8261427506500751 1.0224924986086579 0.8443226908718068 0.8682053787110791 1.0 18.55334949580221 -5.293846920533994 2.20436009493665 0.906571808151715 1.0890039587055773 0.5425218217411245 0.05847873570547568 0.23787149850361786 2.153656546431156 0.015734513156587065 0.05426818596354775 5.083385894076914e-06 5.293846920533994 0.1824321505538623 KNQKPSQVNGAPGS(ph)PTEPAGQK ddPTM_PC-9_Lapatinib_30min_R1 1 KNQKPSQVNGAPGSPTEPAGQK 22 2 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 KNQKPSQVNGAPGS(0.765)PT(0.235)EPAGQK 107.58 8.3859e-05 15095000.0 35860.0 25839.0 30219.0 25628.0 25594.0 24602.0 20946.0 25244.0 24875.0 16459.0 True False 35348.6298240814 25779.171383043416 27734.51046871333 27512.768612501815 24088.611239740043 23549.829810063082 22030.481390434867 26416.928397752832 22073.315554637455 19303.91621976106 1.8311636572425476 1.3354373842885703 1.436729736752692 1.4252428522424638 1.2478613647877823 1.2199508919312216 1.1412441465054988 1.3684750854186942 1.1434630830008168 1.0 14.236605938839999 -1.5228787452803376 0.3318014497328594 1.1474902505467617 7.06864877674287 0.7236621356215556 0.11384996033054108 33.22806422576974 0.47269754522837415 0.10114216322797863 120.87468112146257 0.029999999999999995 1.5228787452803376 5.921158526196108 KNQKPSQVNGAPGSPT(ph)EPAGQK ddPTM_PC-9_Lapatinib_30min_R1 2 KNQKPSQVNGAPGSPTEPAGQK 22 2 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 KNQKPSQVNGAPGS(0.232)PT(0.768)EPAGQK;KNQKPSQVNGAPGS(0.133)PT(0.867)EPAGQK 75.215 0.00042226 70535000.0 182470.0 132951.0 136077.0 120985.0 124415.0 125615.0 124231.0 105809.0 147310.0 95946.0 True False 179867.94433910036 132643.16012798503 124889.27433241018 129882.64049412853 117097.15430930136 120242.73927286695 130663.07331304865 110725.27241474543 130718.39655693033 112530.13825999142 1.5983979680495068 1.1787345344011233 1.1098295644484504 1.1542031539501498 1.040584825718051 1.0685380923913574 1.1611384766200377 0.9839610448084939 1.1616301070822153 1.0 16.77995191583625 -4.077213229188778 1.3475308872942344 1.081943334572507 3.6819736138069574 0.8634737187308383 0.06096873856757511 2.372182092705368 0.9653449871682628 0.016486867354540077 13.412712017507092 8.371181743114126e-05 4.077213229188778 2.6000302792344505 KNQS(ph)SEDILR ddPTM_PC-9_AZD4547_30min_R2 2 KNQSSEDILR 10 1 Q13625-2;Q13625;Q13625-3;H0Y847 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 KNQS(0.753)S(0.247)EDILR;KNQS(0.913)S(0.087)EDILR 78.705 0.0091824 27163000.0 71620.0 65404.0 102521.0 123642.0 118243.0 113447.0 95077.0 126843.0 97683.0 89283.0 True False 94393.6702114567 86544.56395507073 101161.50455396858 95138.24714985765 101827.00047274858 106353.14115596036 103538.66881144555 107242.32891217104 102846.32395620298 86157.2293456303 1.0955977917161763 1.0044956716039066 1.1741499270844329 1.1042398632411785 1.1818741299613649 1.2344076285149757 1.201740928739566 1.2447281525495124 1.1937050986588986 1.0 16.394684235819803 -5.628173020744353 1.2198266230994153 1.1907609043281508 1.0492934165516266 0.23246012583737652 0.07360557980430366 0.6297774893239955 1.7537767880034716 0.023952469528270008 0.07701163297291827 2.354111230938017e-06 5.628173020744353 -0.1414674877765243 KNQS(ph)SEDILR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KNQSSEDILR 10 1 Q13625-2;Q13625;Q13625-3;H0Y847 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 KNQS(0.979)S(0.021)EDILR;KNQS(0.918)S(0.082)EDILR 73.273 0.013012000000000001 19702800.0 86377.0 74523.0 109563.0 128621.0 157397.0 153944.0 143608.0 142616.0 153655.0 126525.0 True False 100998.92007648539 81921.15093465077 112175.3974399911 121414.78236490797 126556.18773381851 145870.90563707644 130004.41060811665 138872.4811141423 155901.9136882993 149462.98092865123 0.6757453882490072 0.5481032856808687 0.7505229505193662 0.81234016350087 0.8467393527647648 0.9759667894400585 0.8698101014737324 0.929142990801418 1.0430804518927788 1.0 17.189428675622246 -5.838442974685855 0.6830891788749474 0.9762038267322332 0.556383226414811 0.8449799843751657 0.057717964741762676 0.3949941792975216 0.32675886729075 0.03187288506756736 0.10634416139974782 1.4506312378608386e-06 5.838442974685855 -0.4198206003174222 KNQS(ph)SEDILR ddPTM_PC-9_Lapatinib_30min_R1 3 KNQSSEDILR 10 1 Q13625-2;Q13625;Q13625-3;H0Y847 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 KNQS(0.649)S(0.351)EDILR;KNQS(0.976)S(0.024)EDILR;KNQS(0.75)S(0.25)EDILR 86.699 0.0050881 43599000.0 267915.0 179438.0 225597.0 176211.0 190591.0 181899.0 164615.0 145961.0 186240.0 147827.0 True False 264094.4829704061 179022.5223356375 207049.2854896033 189170.14476266407 179380.81209632318 174119.60379727941 173137.95923261886 152742.8809168277 165263.69000585642 173378.69998290375 1.5232233428699578 1.0325519937183187 1.1942025491598431 1.0910806505142643 1.0346185091594946 1.004273326622294 0.9986114744757653 0.8809783493121655 0.9531948850819189 1.0 17.4035671451041 -1.5228787452803376 0.5631335967054686 0.9714292093881693 24.099109877369052 0.7660208677709215 0.08203322564294384 70.1180519119835 0.6156425746212039 0.039687308671234725 1971.2047382511496 0.029999999999999995 1.5228787452803376 23.127680667980883 KNQSS(ph)EDILR ddPTM_PC-9_AZD4547_30min_R2 1 KNQSSEDILR 10 1 Q13625-2;Q13625;Q13625-3;H0Y847 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 KNQS(0.405)S(0.595)EDILR 62.891000000000005 0.026376 10349000.0 40855.0 41474.0 62876.0 88533.0 77175.0 72314.0 60657.0 72173.0 62721.0 74888.0 True False 53846.04016320934 54879.65943172595 62042.22315755145 68123.08467121485 66460.58338746807 67792.19414838747 66055.3554918208 61020.321220549005 66036.30401254076 72266.19391413334 0.7451069061031383 0.7594098493264214 0.8585234643915244 0.9426687774944764 0.9196635354345145 0.938090004144097 0.9140561016719344 0.8443826624251628 0.9137924724665182 1.0 16.14103329258503 -5.380600704920884 2.6565342541421586 0.9179195852125303 0.7464852337018454 0.774856216825804 0.036728755559559886 0.13096496653455356 1.7617163704727554 0.010254857486082207 0.02718212024342333 4.162931790833535e-06 5.380600704920884 -0.17143435151068487 KNS(ph)APQLPLLQSSGPFVEGSIVR ddPTM_PC-9_AZD4547_30min_R2 2 KNSAPQLPLLQSSGPFVEGSIVR 23 1 Q8IY18 Q8IY18 SMC5 Structural maintenance of chromosomes protein 5 1 KNS(1)APQLPLLQSSGPFVEGSIVR;KNS(0.999)APQLPLLQS(0.001)SGPFVEGSIVR 75.773 0.00017164 8590700.0 64202.0 59890.0 59434.0 75113.0 60615.0 54655.0 48400.0 55856.0 53967.0 52746.0 True False 84616.90051544161 79248.27128721774 58645.866326514275 57796.85833428171 52199.6535410609 51237.41420997489 52707.506236776106 47224.73864319048 56819.58544418588 50899.378594632886 1.6624348440348953 1.5569595047192604 1.1521921867371918 1.135512061838337 1.0255459886216591 1.0066412523035724 1.0355235700723049 0.9278057993456549 1.1163119671205035 1.0 15.635360422806924 -5.227657135689063 1.4108093488050866 1.019775996529651 1.7442927239988728 0.946256527406178 0.05432639379490529 0.11737449207414853 0.3564345812355082 0.015719811378224473 0.0952854443742669 5.920288412534148e-06 5.227657135689063 0.7245167274692219 KNS(ph)APQLPLLQSSGPFVEGSIVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KNSAPQLPLLQSSGPFVEGSIVR 23 1 Q8IY18 Q8IY18 SMC5 Structural maintenance of chromosomes protein 5 1 KNS(1)APQLPLLQSSGPFVEGSIVR;KNS(1)APQLPLLQSSGPFVEGSIVR;KNS(1)APQLPLLQSSGPFVEGSIVR 96.287 4.081e-06 5998300.0 74635.0 86372.0 70232.0 72363.0 68701.0 53923.1 56423.0 80384.0 54490.4 43999.8 True False 87269.23139155656 94946.44134733797 71906.59723634335 68308.73571401123 55239.53222425493 51095.277709807684 51078.20497285499 78274.00517388833 55287.219014291135 51976.615437774824 1.6790095056503482 1.8267145820798125 1.3834413154975094 1.314220542039503 1.062776630586622 0.9830435721806039 0.9827151026023349 1.5059465591328494 1.0636940968285957 1.0 15.665575072418546 -5.56858831850897 1.681354143389755 1.1193927432015494 1.7702995026248756 0.7152646644814148 0.15738787947911748 0.21727821834754632 1.1973707261572752 0.04988606246109559 0.13723553594767054 2.7002979175179066e-06 5.56858831850897 0.6509067594233262 KNS(ph)GAEAAQLSER ddPTM_PC-9_AZD4547_30min_R2 2 KNSGAEAAQLSER 13 1 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 KNS(1)GAEAAQLSER;KNS(1)GAEAAQLSER 61.495 0.024390000000000002 24116000.0 82801.0 85084.0 81134.0 103434.0 115456.0 75021.0 84480.0 113111.0 78343.0 81224.0 True False 109129.99563220917 112585.73909169514 80058.11014798615 79588.88933936988 99426.92731562712 70329.92501045705 91998.55634055451 95632.29398220268 82484.05103959562 78380.37248266161 1.3923127968848277 1.4364021951618058 1.0214050739003018 1.0154186158910588 1.268518178292929 0.8972900074698499 1.173744821905578 1.2201051226613824 1.052355946099156 1.0 16.25820480854484 -5.256409954648971 24.992968763071698 1.090056785088681 1.4143575340561183 0.6089199108949778 0.10663545443649347 265.8784421225225 1321231.4139024725 0.026858493257849655 0.06653034813686065 5.541024180083733e-06 5.256409954648971 0.3243007489674372 KNS(ph)ITEISDNEDDLLEYHR ddPTM_PC-9_AZD4547_30min_R2 3 KNSITEISDNEDDLLEYHR 19 1 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 KNS(0.908)IT(0.092)EISDNEDDLLEYHR;KNS(0.45)IT(0.45)EIS(0.1)DNEDDLLEYHR;KNS(1)ITEISDNEDDLLEYHR 179.74 2.5493000000000003e-09 12996200.0 28250.2 37363.0 44402.0 54217.0 48334.0 45828.0 44961.0 56888.0 47540.0 49021.0 True False 37233.17595933664 49439.859076712535 43813.200468248564 41718.10829429994 41623.65840557021 42962.36791537333 48962.44189900184 48097.26675619128 50052.86734516643 47304.78971083115 0.7870910363821263 1.04513431681935 0.9261895198366533 0.8819003012024371 0.8799036769851625 0.9082033379283038 1.0350419523753034 1.0167525751663722 1.0580930102666974 1.0 15.529698646459169 -7.260120343874664 24.642047413543857 1.0288679374514067 0.9099270133760845 0.49171511206142104 0.060988846073818825 87.61272168013964 1636794.1435215937 0.023855304353421397 0.017430600204247106 5.493886160723364e-08 7.260120343874664 -0.1189409240753222 KNS(ph)ITEISDNEDDLLEYHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KNSITEISDNEDDLLEYHR 19 1 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 KNS(0.485)IT(0.485)EIS(0.03)DNEDDLLEYHR 61.523999999999994 0.0063405 3676100.0 6953.3 14683.0 9769.3 10190.0 11992.0 7772.0 9411.4 10845.0 9363.2 6340.7 True False 8130.356356064978 16140.631203433544 10002.23716227657 9619.087336425737 9642.253685292293 7364.422638175946 8519.884059364575 10560.330241227328 9500.119086565914 7490.218717046413 1.0854631437613063 2.154894511518111 1.3353731766888524 1.2842198205153068 1.2873127006756464 0.9832052863043669 1.1374679940887207 1.409882760458501 1.2683366728591414 1.0 12.870792131168704 -5.505996071113193 24.493634727313697 1.213412919571115 1.6514176270011482 0.27566945918024055 0.2702209323185126 619.9377189757244 899412.790169993 0.06707560871680304 0.13427642708534449 3.1189177995562027e-06 5.505996071113193 0.4380047074300333 KNS(ph)ITEISDNEDDLLEYHR ddPTM_PC-9_Lapatinib_30min_R1 2 KNSITEISDNEDDLLEYHR 19 1 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 KNS(0.992)IT(0.008)EISDNEDDLLEYHR;KNS(0.46)IT(0.46)EIS(0.079)DNEDDLLEYHR 117.3 2.8756e-05 6984500.0 23475.0 27615.0 33575.0 25957.0 30908.0 30678.0 30553.0 31055.0 34736.0 30967.0 True False 23140.242195212242 27551.05916416055 30814.593103247957 27865.96437001363 29090.052207466008 29365.973453910876 32134.88484302284 32497.928671851307 30823.665893703972 36319.604689066226 0.6371281403891067 0.7585726606890799 0.8484286480277822 0.7672430525765742 0.8009462783669387 0.8085433116718725 0.8847806885050384 0.8947764974334809 0.8486784522460188 1.0 15.148460879638975 -1.7825733548458575 0.10091732154339784 1.085494986572917 9.313699516849785e-18 0.7874013541661261 0.04227683967156895 58.01008428599425 0.4393727652036225 0.5633116153046567 8.689720798999836 0.016497823200248136 1.7825733548458575 -1.085494986572917 KNS(ph)LISSLEEEVSILNR ddPTM_PC-9_AZD4547_30min_R2 2 KNSLISSLEEEVSILNR 17 1 A0A087WY61;Q14980-2;Q14980;H0YFY6;Q14980-4;Q14980-3 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 KNS(0.994)LIS(0.005)SLEEEVSILNR;KNS(0.996)LIS(0.004)S(0.001)LEEEVSILNR 112.3 0.00012345 7781500.0 2955.9100000000003 1350.95 4938.7 3734.9 5431.2 4427.9 2209.03 6039.7 5062.4 6057.4 True False 3895.8278932525304 1787.618168232873 4873.209611110744 2873.8765086297794 4677.171629336139 4151.022713024384 2405.6293905418493 5106.403143498952 5329.988128905567 5845.332269729064 0.6664852763678916 0.30581976964600005 0.8336924893641027 0.49165323304418174 0.8001549635694071 0.7101431572198353 0.4115470737223552 0.8735864631585157 0.9118366386984902 1.0 12.513069319729663 -7.909761142867025 7.077407858340168 0.9352006758395057 0.608190776074064 0.47461255742852126 0.1581616627632228 0.1912098757496361 12.517240175352313 0.08510074464731071 0.04050393804738404 1.2309455910527815e-08 7.909761142867025 -0.3270098997654417 KNS(ph)LISSLEEEVSILNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KNSLISSLEEEVSILNR 17 1 A0A087WY61;Q14980-2;Q14980;H0YFY6;Q14980-4;Q14980-3 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 KNS(0.935)LIS(0.048)S(0.015)LEEEVS(0.003)ILNR;KNS(0.987)LIS(0.012)S(0.001)LEEEVSILNR;KNS(0.995)LIS(0.004)S(0.001)LEEEVSILNR 120.15 4.0932e-05 37083800.0 18535.600000000002 18604.5 19960.1 24648.199999999997 20085.0 17980.2 20814.5 19422.3 19318.7 16653.600000000002 True False 21673.310985212498 20451.43180714292 20436.024483100784 23267.241264542583 16149.488431378895 17037.28665966689 18842.799876069854 18912.48520462789 19601.199440110293 19672.76585017495 1.1016910967310556 1.0395809091054191 1.0387977287351817 1.1827132718267812 0.8209058428474753 0.8660341300974401 0.957811424157335 0.9613536474058985 0.9963621581932253 1.0 14.26391218402994 -6.25932363240571 24.99989796901086 0.9296300416999903 1.0833376871027327 0.5881174420260575 0.0641731345055781 146.07762779696824 1726067.4279866433 0.020264965000788275 0.02488697438086786 5.503973922795283e-07 6.25932363240571 0.1537076454027424 KNS(ph)LISSLEEEVSILNR ddPTM_PC-9_Lapatinib_30min_R1 2 KNSLISSLEEEVSILNR 17 1 A0A087WY61;Q14980-2;Q14980;H0YFY6;Q14980-4;Q14980-3 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 KNS(1)LISSLEEEVSILNR;KNS(0.924)LIS(0.056)S(0.02)LEEEVSILNR 127.58 1.5606e-05 3283920.0 6603.799999999999 4666.91 7318.1 4978.01 5527.63 5490.39 4440.3 4846.9 5241.4 5748.2 True False 6509.628601011402 4656.104056629096 6716.434066682921 5344.109461554557 5202.5056711387115 5255.578818424206 4670.197007445239 5072.104668478376 4651.058337611121 6741.768711004949 0.9655668831215446 0.6906353890528295 0.9962421368326277 0.7926865620339484 0.7716826094384377 0.7795548977889502 0.6927257827492401 0.7523403554617513 0.6898869624552604 1.0 12.718911418479337 -5.981701268961457 24.986656207546922 0.7657982514377546 0.8697414655802482 0.13754604837877715 0.11118519307020332 433.95998889874653 592561.8060872649 0.02925370111496976 0.043382187805959885 1.043034637866099e-06 5.981701268961457 0.10394321414249363 KNS(ph)LVAVPSTVSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KNSLVAVPSTVSAK 14 1 G3V292;H0YK26;Q13362-4 G3V292 PPP2R5C 1 KNS(1)LVAVPSTVSAK 115.53 0.00023171 3444300.0 23402.0 19833.0 14729.0 16649.0 17790.0 10898.0 5253.1 16576.0 7385.2 7579.1 True False 27363.4963894313 21801.88916826926 15080.195220043559 15716.210506786278 14304.177206583541 10326.489695167458 4755.4883388494845 16140.897563723767 7493.194578574262 8953.130833877412 3.056304760552767 2.4351134338140037 1.6843488048875797 1.7553871152332885 1.5976732019215565 1.153394258027979 0.5311536742940662 1.8028215898117825 0.8369356728510039 1.0 13.128176553482184 -1.5228792870549461 0.38298237517024364 1.0108766683154415 32.093091270542516 0.7941874261565123 0.3262811960661612 29.78816708726602 0.4050684674246154 0.24784569953310007 688.8929690462791 0.02999996257555922 1.5228792870549461 31.082214602227076 up KNS(ph)PGNGSALGPR ddPTM_PC-9_AZD4547_30min_R2 1 KNSPGNGSALGPR 13 1 Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5;Q9UKE5-8;Q9UKE5-5;Q9UKE5-7;Q9UKE5-3 Q9UKE5-6 TNIK TRAF2 and NCK-interacting protein kinase 1 KNS(0.999)PGNGS(0.001)ALGPR 58.658 0.029577 20600000.0 8518.9 8637.7 9466.6 16207.0 16155.0 9864.4 8882.9 9018.4 10068.0 11226.0 True False 11227.732995872337 11429.667605570223 9341.066698633442 12470.726545653926 13912.157105598255 9247.577508606277 9673.46089154253 7624.813502215506 10600.173925770632 10832.981156928465 1.0364398158942056 1.0550805396961422 0.8622803421622461 1.1511814121155381 1.2842408663011877 0.8536502902242926 0.8929638805247678 0.7038518198971382 0.9785094031102477 1.0 13.403142696223705 KNS(ph)PGNGSALGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KNSPGNGSALGPR 13 1 Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5;Q9UKE5-8;Q9UKE5-5;Q9UKE5-7;Q9UKE5-3 Q9UKE5-6 TNIK TRAF2 and NCK-interacting protein kinase 1 KNS(0.999)PGNGS(0.001)ALGPR 59.63399999999999 0.027793 13589000.0 9914.0 12843.0 9119.6 12460.0 12118.0 11948.0 9956.5 12296.0 9312.7 3866.9 True False 11592.244389574484 14117.968163569907 9337.045850275592 11761.906595865034 9743.564889790858 11321.4258467481 9013.348241182328 11973.243028688908 9448.880619602516 4567.938359636441 2.537740984424558 3.0906652086902384 2.044039370754276 2.5748829493402257 2.1330333561169903 2.478454163652323 1.9731764160450915 2.6211481167276194 2.0685219185739068 1.0 12.15732746757676 -10.858467144214531 0.25260998996476924 6.985702400410379e-16 2.6270715977416725 0.6763817974955868 0.30172471309295684 11.798437771488878 0.6009164424637651 8.613359942735197 0.47641673642668875 1.3852649817470155e-11 10.858467144214531 2.6270715977416716 KNS(ph)STDQGSDEEGSLQK ddPTM_PC-9_Lapatinib_30min_R1 2 KNSSTDQGSDEEGSLQK 17 1 Q12789;Q12789-3 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 1 KNS(0.333)S(0.333)T(0.333)DQGSDEEGSLQK;KNS(0.752)S(0.177)T(0.066)DQGS(0.004)DEEGSLQK 78.67399999999999 0.0031549 9501600.0 30037.6 38751.0 38217.0 35813.0 44582.0 39532.0 42860.0 41397.0 45946.0 31855.0 True False 29609.258315778778 38661.27444035436 35074.945781886134 38446.80748866582 41959.77441158434 37841.30851359295 45079.08108440937 43320.45574717852 40771.07764717075 37361.094305880564 0.7925158206920705 1.0348003761300202 0.9388093800123356 1.029059994171915 1.1230874039195353 1.0128533228652459 1.2065781776984517 1.1595071437819198 1.0912709706351793 1.0 15.189249091731556 -3.5785510105171006 0.507076253810997 1.1154025356403134 2.4386302205381774e-10 0.5806709518242475 0.07254965986389554 9.556179040818147 0.7343589735810359 0.04044043817112048 8.268781593129916 0.0002639058330777114 3.5785510105171006 -1.1154025353964505 KNS(ph)TGSGHSAQELPTIR ddPTM_PC-9_AZD4547_30min_R2 2 KNSTGSGHSAQELPTIR 17 1 I3L280;O94763-2;O94763-4;O94763-3;O94763 I3L280 URI1 Unconventional prefoldin RPB5 interactor 1 1 KNS(0.992)T(0.007)GSGHSAQELPTIR;KNS(0.959)T(0.04)GS(0.001)GHSAQELPTIR 93.583 0.00084883 55860000.0 10630.6 18032.9 44534.0 79960.0 65150.0 69892.0 39805.0 75136.0 44945.0 64126.0 True False 14010.909669783718 23861.682272420567 43943.45006200132 61526.457369685224 56105.047070859 65521.64219126461 43347.56788749733 63525.457653515565 47320.70094296391 61880.968258435314 0.2264171047109273 0.3856061555592718 0.7101286760491367 0.9942710836832815 0.9066607819797815 1.0588334997866329 0.7004991858961159 1.0265750430441283 0.7647052441929653 1.0 15.917208150523763 -5.299974734173491 2.101746001522302 0.9189660778952442 0.23910313971552016 0.8320338767119737 0.11014395324388253 0.1241202961815451 1.0121986885456993 0.02924447541447446 0.10372875182894645 5.012163919025247e-06 5.299974734173491 -0.6798629381797241 down KNS(ph)TGSGHSAQELPTIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KNSTGSGHSAQELPTIR 17 1 I3L280;O94763-2;O94763-4;O94763-3;O94763 I3L280 URI1 Unconventional prefoldin RPB5 interactor 1 1 KNS(0.88)T(0.097)GS(0.021)GHS(0.002)AQELPTIR;KNS(0.776)T(0.199)GS(0.025)GHSAQELPTIR 73.672 0.0047433 29005000.0 11871.2 15019.4 22043.0 18722.9 23666.0 27909.0 26874.0 29084.0 23935.0 21676.6 True False 13880.759693112428 16510.42677224339 22568.588718543015 17673.916613460806 19028.817187802495 26445.402909013454 24328.30016908893 28320.57581704523 24285.004094428714 25606.395988128825 0.5420817400288418 0.6447774524731109 0.8813652936167142 0.690214922148922 0.7431275059803142 1.0327655216014622 0.9500868525335457 1.1059961671363165 0.9483960220597732 1.0 14.644216592424627 -6.715903150889381 5.028485631156376 1.0112443577383465 0.7028697806492791 0.7492071544910076 0.08900199659226961 0.10472807867289645 5.880614732785393 0.03136589223459772 0.030590043367158374 1.923520632568949e-07 6.715903150889381 -0.30837457708906746 KNS(ph)TGSGHSAQELPTIR ddPTM_PC-9_Lapatinib_30min_R1 2 KNSTGSGHSAQELPTIR 17 1 I3L280;O94763-2;O94763-4;O94763-3;O94763 I3L280 URI1 Unconventional prefoldin RPB5 interactor 1 1 KNS(0.782)T(0.209)GS(0.009)GHSAQELPTIR;KNS(0.787)T(0.207)GS(0.004)GHS(0.002)AQELPTIR 66.467 0.0092111 45890000.0 22939.8 17340.9 32195.0 20797.4 29129.3 33526.1 24704.4 29730.7 47067.0 32979.8 True False 22612.674245355895 17300.748211471717 29548.05137629392 22326.910174092594 27415.971844407253 32092.26685615622 25983.47295244245 31112.096859256457 41765.81882251739 38680.31448717881 0.5846041984185836 0.4472752727283621 0.7639041142255469 0.5772163559190605 0.708783581723326 0.8296795742649327 0.6717492682500055 0.8043392943345651 1.0797693704471125 1.0 15.239311904127618 -7.276071922459232 0.3881953743348231 1.0466964792718878 0.5126514363937152 0.6904694742676565 0.10218012971677991 0.7477258535187329 0.2721861194252471 0.11663581068878824 0.14043576538150754 5.2957573487202766e-08 7.276071922459232 -0.5340450428781726 KNSLISSLEEEVSILNR ddPTM_PC-9_AZD4547_30min_R2 3 KNSLISSLEEEVSILNR 17 1 A0A087WY61;Q14980-2;Q14980;H0YFY6;Q14980-4;Q14980-3 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 0 ;; 149.86 1.7095e-05 1512980.0 14600.28 12060.660000000002 12724.9 20438.899999999998 21964.0 17069.8 12673.2 20608.5 13955.2 15580.98 False True 19242.8653353103 15959.032485939144 12556.159511698037 15727.027382857153 18914.67772623708 16002.422707555199 13801.090248758483 17423.92986121799 14692.843381894552 15035.494632681211 1.2798292178219353 1.061423842435521 0.8351011934390186 1.0459933488767854 1.258001694545124 1.0643096950580042 0.9179006468307586 1.1588531196935328 0.9772105102520624 1.0 13.876084709541722 -7.564609484558135 0.011661056872952182 1.5132279776533136e-05 2.0969467921940748 0.0628619943136276 0.1294247635955436 3691.091177902183 34.931434703674014 3105.7005689476764 3169.206245509753 2.7251506486283818e-08 7.564609484558135 2.0969316599142984 KNSLISSLEEEVSILNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KNSLISSLEEEVSILNR 17 1 A0A087WY61;Q14980-2;Q14980;H0YFY6;Q14980-4;Q14980-3 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 0 161.2 1.9118e-05 8362200.0 29873.0 26553.0 29619.0 29995.0 31733.0 31787.0 34806.0 34230.0 27531.0 24111.0 False True 34929.908881355484 29189.006357336428 30325.229290683023 28314.477395102054 25515.146447246523 30120.033762184612 31508.923706381982 33331.498769682934 27933.588791465103 28482.13343742901 1.2263796515837297 1.0248181169946526 1.0647105968133679 0.9941136417082214 0.8958298894041589 1.0575062373172932 1.106269787535487 1.170259904964888 0.9807407458725318 1.0 14.797769594123489 -4.759276852409717 24.984624503579585 1.0366073915191467 1.2263798972517865 0.4012917512105183 0.07082837996147597 65.25419515985085 753728.3936577269 0.01904530267416861 0.12228558906853629 1.7406968667488512e-05 4.759276852409717 0.18977250573263982 KNSSQSLMVPQS(ph)GSPEPESIR ddPTM_PC-9_Lapatinib_30min_R1 2 KNSSQSLMVPQSGSPEPESIR 21 1 F5H1U9;O75970-5;O75970-3;O75970-2;O75970;A0A075B6R8;B7ZB24;H0YGQ3 F5H1U9 MPDZ Multiple PDZ domain protein 1 KNSSQSLMVPQS(0.709)GS(0.286)PEPES(0.005)IR;KNSSQSLMVPQS(0.791)GS(0.172)PEPES(0.036)IR 119.52 8.349299999999999e-07 14317200.0 120682.0 88184.0 104425.0 80511.0 89939.0 81588.0 71536.0 69399.0 97259.0 71716.0 True False 118961.05254963157 87979.8153660087 95839.57959215676 86432.04751682279 84648.96484687732 78098.67143091722 75239.78405166374 72623.53089350548 86304.66723732586 84112.01504443689 1.4143169972421148 1.0459839217920106 1.139427934778689 1.0275826523851581 1.0063837467472008 0.9285079116183012 0.894518862874871 0.8634144700390072 1.0260682399741652 1.0 16.36002427761511 -1.5228787455009591 0.561185272967996 0.9393340114507868 21.860213307554467 0.7815259578520208 0.06894947126192962 63.593535979996716 0.5618902453835123 0.033417820947705866 1610.4569125388352 0.029999999984760002 1.5228787455009591 20.92087929610368 KNSSQSLMVPQSGS(ph)PEPESIR ddPTM_PC-9_AZD4547_30min_R2 2 KNSSQSLMVPQSGSPEPESIR 21 1 F5H1U9;O75970-5;O75970-3;O75970-2;O75970;A0A075B6R8;B7ZB24;H0YGQ3 F5H1U9 MPDZ Multiple PDZ domain protein 1 KNSSQSLMVPQS(0.251)GS(0.726)PEPES(0.023)IR;KNSSQSLMVPQS(0.236)GS(0.756)PEPES(0.008)IR 104.89 3.3249e-05 14325300.0 54091.0 47192.0 72435.0 105657.0 83884.0 77615.0 62375.0 82660.0 64097.0 81352.0 True False 71290.81283730654 62445.89111014152 71474.46457181178 81299.41103437748 72238.15454323783 72761.72178038963 67926.25416361379 69886.79633783533 67485.03656338107 78503.89124162159 0.9081182054770455 0.7954496283240753 0.9104576020547258 1.0356099519213864 0.9201856545034324 0.9268549702388823 0.8652597099237841 0.890233531516746 0.8596393821507986 1.0 16.26047654611238 -5.497678714635253 24.32477859404866 0.9246904165096722 0.8520763069243875 0.21292631265288997 0.05770429176205074 836.8322819655673 807764.6250926945 0.015571565323086681 0.032174497474298874 3.17922514998468e-06 5.497678714635253 -0.07261410958528469 KNSSQSLMVPQSGS(ph)PEPESIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KNSSQSLMVPQSGSPEPESIR 21 1 F5H1U9;O75970-5;O75970-3;O75970-2;O75970;A0A075B6R8;B7ZB24;H0YGQ3 F5H1U9 MPDZ Multiple PDZ domain protein 1 KNSSQSLMVPQS(0.221)GS(0.772)PEPES(0.006)IR;KNSSQSLMVPQS(0.251)GS(0.726)PEPES(0.023)IR 97.839 0.00010308 12433500.0 74586.0 67371.0 91069.0 94982.0 114124.0 96249.0 93317.0 95697.0 86622.0 67778.0 True False 87211.93665935057 74059.14764057213 93240.43034110556 89660.46647579897 91762.22144598862 91201.53300331911 84477.33820342614 93185.05514935283 87888.68287727617 80065.61486964731 1.0892558160121295 0.9249806894151235 1.1645502316182523 1.1198373561705957 1.1460877630851176 1.1390849012001205 1.0551013483248888 1.1638586089804586 1.0977082112010927 1.0 16.288895172648743 -5.272817091993782 24.999526570897753 1.1172376871933862 1.007118246233443 0.3118131983746373 0.06099880380026892 662.5263663989526 1455729.3363223223 0.014679919380841245 0.031021554684735813 5.335595627853354e-06 5.272817091993782 -0.1101194409599433 KNSSTDQGS(ph)DEEGSLQK ddPTM_PC-9_AZD4547_30min_R2 1 KNSSTDQGSDEEGSLQK 17 1 Q12789;Q12789-3 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 1 KNSSTDQGS(0.999)DEEGS(0.001)LQK 94.45 0.00080096 5723700.0 26114.0 28177.0 32130.0 33425.0 33074.0 37793.0 36258.0 41943.0 29863.0 31898.0 True False 34417.708795056904 37284.66421873322 31703.935206630948 25719.38266110213 28482.245998796476 35429.79773557005 39484.89175894683 35461.673104256304 31441.49721347719 30781.260728995585 1.118138373151033 1.211278009273074 1.029975201008132 0.8355532571437132 0.9253112226156005 1.1510184084888895 1.2827574577461192 1.1520539531004923 1.0214492996337758 1.0 14.909764701866042 -6.796695152414375 24.69578523448986 1.1410406609631527 1.0243096384165842 0.13170968591687304 0.11988404650247117 310.40670422315657 217429.84541919857 0.04698171564055393 0.041435899167466685 1.596999747915504e-07 6.796695152414375 -0.11673102254656853 KNT(ph)EDPEEPLIAS(ph)QST(ph)EPEIGHLSPSK ddPTM_PC-9_Lapatinib_30min_R1 1 KNTEDPEEPLIASQSTEPEIGHLSPSK 27 1 Q8N5R6-6 Q8N5R6-6 3 KNT(0.999)EDPEEPLIAS(0.876)QS(0.128)T(0.333)EPEIGHLS(0.332)PS(0.332)K 48.685 0.014497999999999999 2304000.0 1140.2 1228.0 2609.8 2546.8 1078.6 2346.5 638.16 2328.3 3310.6 1118.9 True False 1123.9405389129288 1225.1566414480944 2395.232318119331 2734.1001678757443 1015.158868609189 2246.1456649586626 671.2008022591385 2436.4813178770364 2937.7253658364925 1312.3003741594657 0.8564659136311058 0.9335946751008227 1.8252165169529027 2.083440820190993 0.7735720332011662 1.711609406800123 0.5114688797441254 1.8566491070595126 2.238607428362671 1.0 10.357882262782455 KNTFTAWS(ph)DEESDYEIDDRDVNK ddPTM_PC-9_Lapatinib_30min_R1 1 KNTFTAWSDEESDYEIDDRDVNK 23 2 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50 Q6PKG0 LARP1 La-related protein 1 1 KNT(0.004)FT(0.01)AWS(0.548)DEES(0.093)DY(0.344)EIDDRDVNK 59.163000000000004 0.017519999999999997 3587600.0 8318.2 7818.8 7633.9 7328.3 7598.1 8602.2 8355.3 6404.0 8220.3 5429.3 True False 8199.580942628945 7800.696048985638 7006.270209706172 7867.247628492159 7151.19469643935 8234.303958707607 8787.896551203123 6701.553218951399 7294.443250403462 6367.7472709124895 1.287673739830123 1.2250322943278196 1.1002745416279975 1.235483648107283 1.1230336871417 1.2931266911803243 1.3800636516065483 1.0524213562249425 1.145529641812901 1.0 12.636567362654727 -7.8057053303547175 24.999778802128265 1.0742312512619587 1.2273470407872087 0.4607564386027657 0.08334170737839786 142.85733585260368 80678.68326466414 0.04711979384985617 0.022635788516430014 1.5642086012279258e-08 7.8057053303547175 0.15311578952524996 KNWSTSWIVLS(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 1 KNWSTSWIVLSSR 13 1 B8ZZK0;Q53QZ3 B8ZZK0 ARHGAP15 Rho GTPase-activating protein 15 1 KNWS(0.041)T(0.03)S(0.004)WIVLS(0.462)S(0.462)R 52.576 0.042109 73740000.0 219850.0 219070.0 277330.0 257740.0 287990.0 294420.0 268100.0 296460.0 306600.0 249510.0 True False 216714.89868444778 218562.75687462074 254528.9979247585 276695.0593954353 271050.99441012496 281828.3429265416 281980.90617662517 310234.6138804393 272067.47935886803 292637.4710488229 0.7405575844669994 0.7468720806371247 0.8697758254010249 0.9455216326321799 0.9262347485394428 0.9630630756767373 0.963584414415542 1.0601329104182988 0.9297082782453275 1.0 18.158754987027116 -5.336604778073891 0.845248846439505 0.9865480591102173 0.6685210054982018 0.8665068942418693 0.03560661073614065 0.39874627693887066 0.37704879250915724 0.01411328909587555 0.10170840755648881 4.606756124851881e-06 5.336604778073891 -0.31802705361201544 KPAATS(ph)PLSPMANGGR ddPTM_PC-9_Lapatinib_30min_R1 1 KPAATSPLSPMANGGR 16 1 Q86UU1-3;Q86UU1-2;Q86UU1;A0A087WXY7 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 KPAAT(0.117)S(0.743)PLS(0.14)PMANGGR 58.93 0.019188999999999998 7656600.0 25147.0 18845.0 24127.0 18884.0 42182.0 45929.0 48672.0 45041.0 41862.0 36502.0 True False 24788.399168605 18801.36556033334 22143.371192913284 20272.792355177313 39700.93769300283 43964.723735728294 51191.998006074995 47133.76929025453 37147.06073359728 42811.32206414231 0.5790150355895489 0.4391680670866479 0.517231660347626 0.473538105756311 0.9273466872506453 1.0269415102354909 1.1957584007654865 1.100965048910101 0.8676924454222994 1.0 15.385704767897437 -6.358123842302241 3.234370073195474 1.0502932152545317 0.4951230451354435 0.8978193268358989 0.08597803649801063 0.0755132609881104 1.509194846722452 0.028971424438641688 0.03373894673224 4.38405665312091e-07 6.358123842302241 -0.5551701701190882 KPAATSPLS(ph)PMANGGR ddPTM_PC-9_AZD4547_30min_R2 2 KPAATSPLSPMANGGR 16 1 Q86UU1-3;Q86UU1-2;Q86UU1;A0A087WXY7 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 KPAAT(0.046)S(0.353)PLS(0.602)PMANGGR;KPAAT(0.004)S(0.023)PLS(0.974)PMANGGR 85.177 0.0017839000000000002 25489000.0 112068.0 112182.0 158664.0 201199.0 167811.0 174619.0 148259.0 168375.0 131476.0 154316.0 True False 147703.29284079166 148442.63766142336 156560.01169078404 154815.67904356276 144513.33927870973 163700.0463257085 161453.76378426023 142356.51262258692 138425.5529464261 148913.4438101349 0.99187346059308 0.9968383905665911 1.0513490769201372 1.039635341728805 0.9704519322175148 1.0992966258602317 1.0842121413169001 0.9559681717125011 0.9295705572622383 1.0 17.184114479818795 -7.789067461069456 24.895347444182278 0.9570769197453368 1.0330208539613204 0.38702003130863005 0.041121858605732343 221.9481409641842 199991.5681569512 0.023436224589947884 0.01126230178276706 1.625296270984e-08 7.789067461069456 0.07594393421598356 KPAATSPLS(ph)PMANGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPAATSPLSPMANGGR 16 1 Q86UU1-3;Q86UU1-2;Q86UU1;A0A087WXY7 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 KPAAT(0.031)S(0.099)PLS(0.87)PMANGGR 46.41 0.044407999999999996 7154200.0 31947.0 33973.0 33079.0 40122.0 77618.0 65344.0 90314.0 83959.0 75653.0 59256.0 True False 37354.996117988296 37345.614920264794 33867.728812806075 37874.09441727907 62409.31008547503 61917.2456084623 81758.80410326319 81755.16521191364 76759.28200358554 69998.64372976201 0.5336531413694477 0.5335191216624414 0.4838340717508245 0.5410689750432374 0.8915788472475767 0.8845492185177344 1.1680055462060472 1.1679535610366831 1.0965824180811812 1.0 16.095039348702734 -6.545841292623106 1.3614047930690512 1.1149247030267857 0.5032819631861957 0.9283304305224497 0.0715460992885435 0.09830499604023346 0.3772002198796177 0.030666832733959 0.033514924718906804 2.845500769418861e-07 6.545841292623106 -0.61164273984059 KPAATSPLS(ph)PMANGGR ddPTM_PC-9_Lapatinib_30min_R1 1 KPAATSPLSPMANGGR 16 1 Q86UU1-3;Q86UU1-2;Q86UU1;A0A087WXY7 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 KPAATS(0.001)PLS(0.999)PMANGGR 68.134 0.010895 8200900.0 32035.0 26601.0 21655.0 24520.0 56974.0 57093.0 49800.0 58430.0 60713.0 53790.0 True False 31578.17502550049 26539.407018860555 19874.609490717354 26323.282596322148 53622.90133519373 54651.26548028336 52378.40032672856 61144.87110920214 53874.862603766975 63087.52982933029 0.50054543442941 0.42067595752531756 0.31503229789601567 0.4172501707949909 0.8499762390484923 0.8662768320162569 0.8302496621507773 0.969206930032233 0.8539700753780312 1.0 15.945067243214886 -6.277433896562833 4.572619903965455 0.892775567425478 0.4034341777113674 0.9312162908921298 0.06419814708888306 0.047779502643521286 2.67215952150431 0.020176754525690007 0.024219510804106965 5.279175543582672e-07 6.277433896562833 -0.4893413897141106 KPALPVS(ph)PAAR ddPTM_PC-9_AZD4547_30min_R2 2 KPALPVSPAAR 11 1 Q9BWU0;A0A087X0M4;A0A087WWF4 Q9BWU0 SLC4A1AP Kanadaptin 1 KPALPVS(1)PAAR;KPALPVS(1)PAAR 89.62899999999999 0.013483000000000002 38899000.0 82769.0 111043.0 113793.0 113259.0 108674.0 125163.0 105182.0 152984.0 141561.0 99511.0 True False 109087.8202978504 146935.4781857825 112284.03046897471 87148.88738410668 93586.49094978577 117336.53782386007 114542.99423546671 129343.83802259118 149043.62545749068 96027.15017879121 1.136010181440788 1.5301451507433679 1.169294624071579 0.9075442437044705 0.974583654472082 1.2219100286262092 1.192818843652042 1.3469507090626789 1.552098809347034 1.0 16.551154742576024 -7.676623727565262 3.9886025600915898 1.337496599013425 1.1582930709522472 0.08372689459489036 0.19996026419327234 0.49454554134288264 14.866223645276936 0.10939021329524619 0.05824820863140327 2.1056019417585773e-08 7.676623727565262 -0.1792035280611779 KPALPVS(ph)PAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPALPVSPAAR 11 1 Q9BWU0;A0A087X0M4;A0A087WWF4 Q9BWU0 SLC4A1AP Kanadaptin 1 KPALPVS(1)PAAR 71.176 0.044632 10926000.0 28566.0 46792.0 37164.0 46050.0 39286.0 32091.0 46908.0 28659.0 34246.0 29766.0 True False 33401.659595782185 51437.20052244521 38050.13070525484 43469.967796114346 31588.190316910688 30408.091467023183 42464.53465548944 27906.7316167205 34746.78296293321 35162.340172473654 0.9499270933602482 1.4628491809743682 1.0821273703233738 1.2362649238614727 0.8983529014840446 0.8647914592108898 1.2076708901397926 0.7936539911688498 0.9881817533331938 1.0 15.101743469452632 -6.258938003516794 24.977991563140886 0.9562034636052048 1.195605883000543 0.32332397989115236 0.1583064684202659 246.7799733305493 2464267.2677071155 0.045323102244834344 0.05579563238034683 5.508863310162489e-07 6.258938003516794 0.23940241939533813 KPALPVS(ph)PAAR ddPTM_PC-9_Lapatinib_30min_R1 2 KPALPVSPAAR 11 1 Q9BWU0;A0A087X0M4;A0A087WWF4 Q9BWU0 SLC4A1AP Kanadaptin 1 KPALPVS(1)PAAR;KPALPVS(1)PAAR 99.669 0.0065611 34380000.0 72205.0 129064.0 133010.0 125355.0 141044.0 120346.0 132389.0 141826.0 114463.0 113713.0 True False 71175.34345922472 128765.16023766872 122074.43123344769 134574.02487202108 132748.06922317302 115199.08212022821 139243.45463564794 148415.7537212683 101570.97159117457 133368.1405369515 0.5336757577384428 0.9654866576024019 0.9153192864650104 1.0090417721219969 0.9953506788706655 0.8637676258844644 1.0440533554343783 1.112827644771336 0.7615834725013123 1.0 17.025054545915303 -4.761411710009956 10.0715895521321 0.9670651536700854 0.5319599103539105 0.6574119926720798 0.09294700165707565 0.04246885861184416 94.93815754456757 0.022179319241129276 0.1254882266890058 1.732161135028592e-05 4.761411710009956 -0.43510524331617484 KPALVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPALVAK 7 1 P29692-2;P29692;E9PRY8;A0A087X1X7;E9PK01;P29692-3;E9PI39;E9PQ49;P29692-4;E9PL71;E9PQZ1;H0YE72;H0YE58;P24534 P29692-2;P24534 EEF1D;EEF1B2 Elongation factor 1-delta;Elongation factor 1-beta 0 80.462 0.042768 0.0 56869.0 75572.0 57772.0 68591.0 91409.0 83931.0 67317.0 74856.0 84177.0 70256.0 False True 66495.79848605114 83074.28872205142 59149.5035815301 64748.068645022424 73498.06263499691 79529.51060791881 60940.24642712514 72891.10931648791 85407.92937776154 82992.85665380981 0.8012231554268187 1.000981193701782 0.7127059600835517 0.7801643569772236 0.8855950451444421 0.9582693476820814 0.7342830321087358 0.8782817251434112 1.0290997661886225 1.0 16.340699545965336 -8.186488468367175 4.592498254810624 1.0147730810127833 0.8424718785524349 0.38627060232578414 0.08680777630788866 0.22105812998230784 8.471115517575026 0.06525134120722642 0.022439041825526564 6.508958935670274e-09 8.186488468367175 -0.1723012024603484 KPALVAK ddPTM_PC-9_Lapatinib_30min_R1 1 KPALVAK 7 1 P29692-2;P29692;E9PRY8;A0A087X1X7;E9PK01;P29692-3;E9PI39;E9PQ49;P29692-4;E9PL71;E9PQZ1;H0YE72;H0YE58;P24534 P29692-2;P24534 EEF1D;EEF1B2 Elongation factor 1-delta;Elongation factor 1-beta 0 94.006 0.015674 0.0 83443.0 68632.0 56677.0 57698.0 85702.0 61758.0 76823.0 101390.0 88440.0 84407.0 False True 82253.08751842797 68473.08682073753 52017.23583954685 61941.3033948856 80661.17685661485 59116.75430492952 80800.5190421741 106100.94954239279 78478.95588551307 98996.63748474217 0.8308674881114544 0.6916708340855611 0.5254444712585717 0.6256909827309265 0.8147870362672341 0.597159214766672 0.8161945808980376 1.0717631652766546 0.7927436514963311 1.0 16.59509190306016 -7.517912774604104 5.935405093833344 0.9498208138927507 0.6795085292282486 0.5643989683062867 0.10815256050455474 0.11420215124603172 16.142751396361145 0.04909898962827021 0.03001036601808368 3.0345005839157734e-08 7.517912774604104 -0.2703122846645022 KPATPAEDDEDDDIDLFGS(ph)DNEEEDKEAAQLR ddPTM_PC-9_AZD4547_30min_R2 3 KPATPAEDDEDDDIDLFGSDNEEEDKEAAQLR 32 2 P29692-2;P29692;E9PRY8;A0A087X1X7;E9PK01;P29692-3;E9PI39;E9PQ49;P29692-4;E9PL71;E9PQZ1;H0YE72 P29692-2 EEF1D Elongation factor 1-delta 1 KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLR;KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLR;KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLR 110.36 2.1122e-16 54748700.0 309586.0 345816.0 300441.0 225555.0 283732.0 358353.0 398347.0 366288.0 388961.0 321806.0 True False 408027.9082111687 457594.2591995408 296456.9560353376 173556.7795400119 244340.70937082105 335945.1302604903 433799.11129960854 309686.60606088734 409520.6843803801 310539.66989012255 1.3139316737070668 1.4735452619030933 0.9546508378148022 0.55888762811341 0.7868260742895602 1.081810676166935 1.3969201147573145 0.9972529634312517 1.3187387122723475 1.0 18.24441805173305 -7.0056827924414495 24.820826182716814 1.1867656602331695 1.0059622492791676 0.07497083160465956 0.26389136712208816 679.1027430643302 2966137.740029261 0.10658615666505843 0.09116289409818276 9.870001247433793e-08 7.0056827924414495 -0.180803410954002 KPATPAEDDEDDDIDLFGS(ph)DNEEEDKEAAQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KPATPAEDDEDDDIDLFGSDNEEEDKEAAQLR 32 2 P29692-2;P29692;E9PRY8;A0A087X1X7;E9PK01;P29692-3;E9PI39;E9PQ49;P29692-4;E9PL71;E9PQZ1;H0YE72 P29692-2 EEF1D Elongation factor 1-delta 1 KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLR;KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLR 106.06 4.7324999999999995e-16 12744900.0 62476.0 75638.0 53026.0 62940.0 64496.0 46402.0 67618.0 48671.0 46104.0 48203.0 True False 73051.9528427532 83146.84076587275 54290.34094222485 59413.675854233166 51858.47178840992 43968.597433947514 61212.733528073775 47393.43782118719 46778.18377980119 56941.822325261914 1.2829226368181077 1.4602068808216757 0.9534352559373438 1.0434101584394608 0.9107272944688181 0.772167023085264 1.075004821208841 0.8323133311481913 0.8215083723979856 1.0 15.797201044346322 -5.275445569017191 16.81058384383506 0.9235444654104772 1.3715639747466724 0.7576155205559871 0.10078476264272548 4.238093897745063 5087.855483170891 0.026347948059391838 0.0560323069900678 5.303400570279823e-06 5.275445569017191 0.44801950933619517 KPATPAEDDEDDDIDLFGS(ph)DNEEEDKEAAQLR ddPTM_PC-9_Lapatinib_30min_R1 2 KPATPAEDDEDDDIDLFGSDNEEEDKEAAQLR 32 2 P29692-2;P29692;E9PRY8;A0A087X1X7;E9PK01;P29692-3;E9PI39;E9PQ49;P29692-4;E9PL71;E9PQZ1;H0YE72 P29692-2 EEF1D Elongation factor 1-delta 1 KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLR;KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLR 111.3 1.5348e-16 69309000.0 153057.0 251898.0 180348.0 207857.0 256191.0 239662.0 225871.0 242375.0 219927.0 222218.0 True False 150874.3791127839 251314.74565756644 165520.4836034119 223143.49717062528 241122.3490708854 229412.21493940885 237565.49518470914 253636.62733343904 195156.5053260203 260628.08521312737 0.5788876474667229 0.9642657868282116 0.6350830666160108 0.8561759450757226 0.9251587328883176 0.8802282944748956 0.9115114934387869 0.9731745798847001 0.7487930748769152 1.0 17.99163303115367 -3.336734951005712 0.39895503174231395 0.9190602866444253 2.219200711126756e-14 0.335854016148898 0.11262136829541079 22.070870153544615 1.1152341407629398 0.08154389655369973 12.295344289281298 0.00046053755291654123 3.336734951005712 -0.9190602866444031 KPDS(ph)PPKVLEPENK ddPTM_PC-9_Lapatinib_30min_R1 2 KPDSPPKVLEPENK 14 2 Q96T23-3;Q96T23-2;Q96T23;H0YCN2 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 KPDS(1)PPKVLEPENK;KPDS(1)PPKVLEPENK 51.135 0.031291 18787200.0 67348.0 98454.0 97372.0 119969.0 130980.0 104358.0 105261.0 101935.0 98619.0 105874.0 True False 66387.60516988952 98226.03581199558 89366.4500267895 128791.92046485226 123276.013916588 99894.85161037966 110710.8995339713 106671.27223201301 87511.48971589108 124174.17983176265 0.5346329265861449 0.7910343031464117 0.7196862515852137 1.0371876072734763 0.9927668866716773 0.8044736171861345 0.8915774574389613 0.8590455147482073 0.7047478778153075 1.0 16.922005692268485 -4.537900435487854 1.2372973031291716 0.8842666802579866 0.21655707970673363 0.5008952228170287 0.10481087461807534 2.124036128328208 1.903966169401981 0.03201190170850912 2.0935823255858854 2.8980078965571336e-05 4.537900435487854 -0.667709600551253 KPEDWDEEMDGEWEPPVIQNPEYK ddPTM_PC-9_AZD4547_30min_R2 1 KPEDWDEEMDGEWEPPVIQNPEYK 24 1 P27797;K7EJB9;K7EL50 P27797 CALR Calreticulin 0 69.133 0.00081652 3449700.0 8280.9 9736.2 9877.4 8655.3 10454.0 8795.2 8626.8 7812.2 8396.5 10241.0 False True 10914.053946579868 12883.236248231915 9746.419222221488 6659.954308051975 9002.642549175136 8245.234753628602 9394.568487673963 6605.003996496938 8840.321848205509 9882.465707117799 1.1043857140550535 1.30364593513872 0.9862335484960677 0.6739162578884715 0.9109712915766583 0.8343297106196899 0.9506300113854754 0.6683558731440591 0.8945461699743931 1.0 13.270655328457856 -5.484996234257414 5.345779793489167 0.8388177497918978 1.1959197091473794 0.6177937989050888 0.11115133979020937 0.11113406892477393 8.188761442613378 0.027874870701028256 0.05702396698158178 3.2734353324356635e-06 5.484996234257414 0.3571019593554816 KPEEES(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 KPEEESPR 8 1 P49321;P49321-3;P49321-4;P49321-2;H0YF33;Q5T624 P49321 NASP Nuclear autoantigenic sperm protein 1 KPEEES(1)PR;KPEEES(1)PR 93.839 0.008365799999999998 5896400.0 34039.0 47332.0 30758.0 38439.0 52219.0 28447.0 66310.0 70106.0 35836.0 43253.0 True False 33553.59761801192 47222.40566206943 28229.195969313492 41265.93228874501 49147.58108650406 27230.38812319585 69743.20734267814 73363.38069453574 31799.77231019047 50729.223419000264 0.6614254143193656 0.9308718422916489 0.5564681275751691 0.8134548393912364 0.9688218698040663 0.536779124298538 1.3748132268186137 1.446175907101665 0.6268531266000043 1.0 15.6305294548986 -7.2610323883646215 24.9999939959548 1.149141888123985 0.7578672893302586 0.3419701810721859 0.2470730128795048 40.464331998607726 2485690.5067552403 0.09644943647047155 0.07002928087790145 5.4823607761316593e-08 7.2610323883646215 -0.3912745987937264 KPEKPLFSSAS(ph)PQDSSPR ddPTM_PC-9_AZD4547_30min_R2 2 KPEKPLFSSASPQDSSPR 18 2 Q5VW31;A0A1B0GWB8;A0A2R8Y7V8;Q5VW30;Q5VW27;A0A1B0GWI9;A0A1B0GU97;A0A0A0MRX8;A0A1B0GWJ4;A0A1B0GVN4;U3KQE8;A0A1B0GW37;Q5VW26;O00712-4;O00712;O00712-5;O00712-6 Q5VW31 NFIB Nuclear factor 1;Nuclear factor 1 B-type 1 KPEKPLFS(0.021)S(0.111)AS(0.771)PQDS(0.028)S(0.069)PR;KPEKPLFS(0.019)S(0.082)AS(0.525)PQDS(0.187)S(0.187)PR 62.19 0.006848899999999999 33475000.0 90919.0 93569.0 119807.0 154330.0 140293.0 130744.0 111862.0 142410.0 99617.0 123074.0 True False 119829.35076731938 123813.34940847674 118218.28089949692 118751.6028747313 120815.73858345379 122568.55701159949 121817.50129459164 120403.80675624376 104882.5512478637 118765.21672080991 1.0089599806735587 1.0425051444105378 0.9953948147747778 0.9998853717742071 1.0172653401329126 1.0320240251801196 1.0257001558036722 1.0137968849859955 0.8831083219796482 1.0 16.85775284414337 -8.146845911861874 9.2206750997626 0.9417926021387225 1.0175307995993268 0.5138406439731132 0.029343918585905696 0.23291459352678665 16.947867318598806 0.018341880153800373 0.006909442327647066 7.131059960036274e-09 8.146845911861874 0.07573819746060428 KPEKPLFSSAS(ph)PQDSSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPEKPLFSSASPQDSSPR 18 2 Q5VW31;A0A1B0GWB8;A0A2R8Y7V8;Q5VW30;Q5VW27;A0A1B0GWI9;A0A1B0GU97;A0A0A0MRX8;A0A1B0GWJ4;A0A1B0GVN4;U3KQE8;A0A1B0GW37;Q5VW26;O00712-4;O00712;O00712-5;O00712-6 Q5VW31 NFIB Nuclear factor 1;Nuclear factor 1 B-type 1 KPEKPLFS(0.05)S(0.132)AS(0.366)PQDS(0.319)S(0.133)PR 50.776 0.021287 11736000.0 27994.0 24375.0 35554.0 37715.0 39374.0 35447.0 38437.0 33268.0 29914.0 19918.0 True False 32732.831293297146 26794.788911236985 36401.74219929588 35601.95082367977 31658.94734862397 33588.09691912283 34795.969100218485 32394.75025035969 30351.43565827203 23528.975729198766 1.3911711104651558 1.1387996324032688 1.5471027136180173 1.513110950235662 1.3455301970215452 1.4275205731731446 1.4788560921943454 1.3768023998664234 1.289959920380503 1.0 14.522150897622536 -10.420505550339561 5.944903269353271 0.9999998916813276 1.3927730390173771 0.5234410601001775 0.11157019617859701 19615085.881329954 34382240.89129828 19.91404881166178 0.02770481043289612 3.797470857235265e-11 10.420505550339561 0.3927731473360495 KPEKPLFSSAS(ph)PQDSSPR ddPTM_PC-9_Lapatinib_30min_R1 1 KPEKPLFSSASPQDSSPR 18 2 Q5VW31;A0A1B0GWB8;A0A2R8Y7V8;Q5VW30;Q5VW27;A0A1B0GWI9;A0A1B0GU97;A0A0A0MRX8;A0A1B0GWJ4;A0A1B0GVN4;U3KQE8;A0A1B0GW37;Q5VW26;O00712-4;O00712;O00712-5;O00712-6 Q5VW31 NFIB Nuclear factor 1;Nuclear factor 1 B-type 1 KPEKPLFS(0.001)S(0.066)AS(0.35)PQDS(0.239)S(0.345)PR 56.746 0.011562000000000001 13003000.0 64907.0 57338.0 67786.0 51529.0 82458.0 76549.0 60710.0 71575.0 75866.0 65784.0 True False 63981.41427751396 57205.23738383625 62212.89674152696 55318.61455570492 77607.98255866543 73275.17771443463 63853.26674368856 74900.63579738383 67321.17217560291 77154.67674832974 0.8292616465261653 0.7414357728493061 0.8063399312067463 0.7169832975407089 1.005875286235912 0.9497179017864383 0.8276007292723297 0.9707854268083016 0.8725481722280729 1.0 16.235465988284922 -6.2574785017883885 24.999251408439598 0.9313843308930785 0.7735598300727471 0.6496346373641659 0.05898169770684609 221.05285546763312 1395183.1809535744 0.01721720747659914 0.021403323760698006 5.527407687431586e-07 6.2574785017883885 -0.1578245008203314 KPEKPLFSSASPQDSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 KPEKPLFSSASPQDSSPR 18 2 Q5VW31;A0A1B0GWB8;A0A2R8Y7V8;Q5VW30;Q5VW27;A0A1B0GWI9;A0A1B0GU97;A0A0A0MRX8;A0A1B0GWJ4;A0A1B0GVN4;U3KQE8;A0A1B0GW37;Q5VW26;O00712-4;O00712;O00712-5;O00712-6 Q5VW31 NFIB Nuclear factor 1;Nuclear factor 1 B-type 1 KPEKPLFS(0.021)S(0.031)AS(0.327)PQDS(0.175)S(0.447)PR 50.873000000000005 0.021074000000000002 12511000.0 63232.0 55513.0 69995.0 48508.0 70594.0 62249.0 58944.0 51999.0 61920.0 54206.0 True False 62330.30008467138 55384.46305920856 64240.281288513565 52075.44013794434 66441.79971314396 59586.75537950644 61995.831904793 54415.06337168234 54945.917553493455 63575.434875045146 0.9804148443054926 0.8711613718107379 1.0104575991461977 0.8191126059978423 1.045086043748384 0.9372606809001262 0.9751538786426426 0.8559133489001353 0.8642633378991014 1.0 15.956181804965425 -10.74922537651481 5.2181321766645805 1.0000065070287096 0.9291357849565088 0.08383095532690754 0.07064489564176415 5.110573180134836e-06 7.577090113221098e-07 0.0653639797500996 0.01585163814192749 1.7814540444387602e-11 10.74922537651481 -0.0708707220722008 KPENEVAQNGGAETSHTEPVS(ph)PIPK ddPTM_PC-9_AZD4547_30min_R2 2 KPENEVAQNGGAETSHTEPVSPIPK 25 1 O95104-2;O95104-3;O95104 O95104-2 SCAF4 Splicing factor, arginine/serine-rich 15 1 KPENEVAQNGGAET(0.001)S(0.002)HT(0.005)EPVS(0.992)PIPK;KPENEVAQNGGAET(0.003)S(0.009)HT(0.043)EPVS(0.945)PIPK 45.445 0.017109 18278100.0 67343.0 97377.0 65473.0 55117.0 64315.0 95224.0 71833.0 90733.0 83827.0 63921.0 True False 88756.6731785832 128852.21093897813 64604.78524070177 42410.6271991613 55385.97240770986 89269.6282267065 78225.99784104017 76712.29968692006 88257.92408378769 61683.14524603817 1.4389128962953446 2.0889371063200466 1.0473652888971523 0.6875561716251051 0.8979109639560287 1.4472288640702895 1.2681908085104419 1.2436509095140085 1.4308272337888992 1.0 15.912588710223472 -5.275485819676255 24.976472867535946 1.129025994031475 1.763925008640317 0.47772028234739905 0.26603281199442264 607.7805209361649 1080716.1648170091 0.07415878098043283 0.15558900086151115 5.302909070881636e-06 5.275485819676255 0.634899014608842 KPENEVAQNGGAETSHTEPVS(ph)PIPK ddPTM_PC-9_Lapatinib_30min_R1 2 KPENEVAQNGGAETSHTEPVSPIPK 25 1 O95104-2;O95104-3;O95104 O95104-2 SCAF4 Splicing factor, arginine/serine-rich 15 1 KPENEVAQNGGAET(0.002)S(0.002)HT(0.007)EPVS(0.988)PIPK;KPENEVAQNGGAETSHT(0.004)EPVS(0.995)PIPK 72.822 0.00010416 17957400.0 125930.0 268537.0 224733.0 220024.0 318240.0 306393.0 381100.0 403090.0 279508.0 287103.0 True False 124134.21510726614 267915.2190753638 206256.3202344669 236205.29893854778 299521.7488839132 293289.28562696755 400831.4932633788 421819.03295239265 248026.8656902753 336728.37100929866 0.3686479245428304 0.7956419539949172 0.6125302706636834 0.7014713320132595 0.8895055322666648 0.8709966574775739 1.190370422491991 1.2526982258371815 0.7365784621796128 1.0 18.361225754824424 -6.387538436746493 1.139761145787986 1.0564353269202895 0.5904436470202205 0.568322745799346 0.16462629765401826 0.3530028365201631 0.9585405423112738 0.07248486764800412 0.09465735588796423 4.096958485369233e-07 6.387538436746493 -0.46599167990006907 KPES(ph)PYGNLCDAPDSPRPVK ddPTM_PC-9_Lapatinib_30min_R1 1 KPESPYGNLCDAPDSPRPVK 20 2 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 KPES(0.818)PY(0.182)GNLCDAPDSPRPVK 43.955 0.029841000000000003 13987000.0 50407.0 46748.0 51806.0 40989.0 45576.0 32310.0 26887.0 20640.0 31460.0 22317.0 True False 49688.186936488324 46639.75787818858 47546.71065694311 44003.46779529562 42895.30928586356 30928.17661828866 28279.07730089863 21599.00975002449 27916.643511513324 26174.46371446672 1.898345940475773 1.7818801709549685 1.8165304617364089 1.6811602436375703 1.6388228524489372 1.1816164394304112 1.0804071330511609 0.8251939747704033 1.0665602862412686 1.0 14.675872357797973 -6.785009036462472 1.4274181639443617 0.9568262128960076 1.8154094942648706 0.9580483414622503 0.07813041529835274 0.06985667965139226 0.29676100032550856 0.03467311679752429 0.03073518808095659 1.6405556374361322e-07 6.785009036462472 0.8585832813688631 KPESPYGNLCDAPDS(ph)PRPVK ddPTM_PC-9_AZD4547_30min_R2 1 KPESPYGNLCDAPDSPRPVK 20 2 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 KPESPYGNLCDAPDS(1)PRPVK 82.709 0.002878 9648000.0 35381.0 31189.0 43071.0 56470.0 48960.0 43519.0 29950.0 40116.0 38111.0 46247.0 True False 46631.42202948255 41270.23431586295 42499.85039790853 43451.71395280293 42162.74911111676 40797.75005038692 32615.49197916207 33916.99397397288 40125.46965485144 44627.90660649123 1.044893780043447 0.9247629444008045 0.9523155717935204 0.9736444582969253 0.9447619733295779 0.914175751287711 0.7308317700570358 0.7599951813343531 0.8991116255723072 1.0 15.44565851418613 -7.031990397665921 5.732514593957356 0.8261419148824176 0.9622997835601671 0.3434505384652825 0.07605593012803558 0.18626752127193322 17.986859247262075 0.028024031690295822 0.022366953226906832 9.289869266315361e-08 7.031990397665921 0.13615786867774948 KPESPYGNLCDAPDS(ph)PRPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KPESPYGNLCDAPDSPRPVK 20 2 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 KPESPYGNLCDAPDS(1)PRPVK;KPESPYGNLCDAPDS(1)PRPVK 67.994 0.0016909000000000002 29294000.0 46888.0 41966.0 52343.0 59261.0 87048.0 95810.0 100489.0 111362.0 90781.0 79645.0 True False 54825.21231978701 46132.107136368075 53591.055631932926 55940.79829675422 69991.56927929648 90785.5549361344 90969.95444264276 108438.86549779246 92108.50038422126 94084.00803052682 0.5827261557776985 0.49032888906475897 0.5696085525453443 0.5945834947699451 0.7439263137746723 0.9649414054158685 0.9669013506857227 1.1525748930956259 0.9790027265243145 1.0 16.521661900635685 -6.6046608877935835 1.4253798448235817 1.0439527488609999 0.5386211724826876 0.9438412052520776 0.05260379897317923 0.0801231006887238 0.33754717933683676 0.021591818925241812 0.022351147138440473 2.485072779000807e-07 6.6046608877935835 -0.5053315763783123 KPFSQHVR ddPTM_PC-9_AZD4547_30min_R2 1 KPFSQHVR 8 1 Q02878;F8VZ45;U3KQR5;F8VR69 Q02878 RPL6 60S ribosomal protein L6 0 80.219 0.0077804 3172000.0 6244.0 6951.6 21494.0 45220.0 28679.0 23370.0 13157.0 30625.0 16357.0 23743.0 False True 8229.462116731838 9198.56875405281 21208.97551606989 34795.22764203557 24697.415885574293 21908.670205600803 14327.94751151369 25892.609942489784 17221.59762652266 22911.764796806754 0.3591806301136083 0.4014779671330612 0.9256805708404364 1.5186620476692845 1.077935990728065 0.9562192349606455 0.6253532907037609 1.1301010713106865 0.7516486739128388 1.0 14.483800967198693 -5.2805884216909025 4.681389070200351 1.0131695282178346 0.36992330431678966 0.5527275138622405 0.2231356469284763 0.1377672575181289 8.2784966954918 0.06225825389257103 0.14900037518849915 5.240968848227026e-06 5.2805884216909025 -0.6432462239010449 KPGDGEVS(ph)PSTEDAPFQHSPLGK ddPTM_PC-9_Lapatinib_30min_R1 1 KPGDGEVSPSTEDAPFQHSPLGK 23 1 O60318 O60318 MCM3AP Germinal-center associated nuclear protein 1 KPGDGEVS(0.914)PS(0.043)T(0.043)EDAPFQHSPLGK 70.501 0.00036387 9323300.0 69379.0 54618.0 77430.0 59648.0 79282.0 77423.0 77383.0 70509.0 92367.0 67139.0 True False 68389.64273744947 54491.53537671991 71064.00428844344 64034.71289989493 74618.78863440925 74111.798771828 81389.51310207299 73785.10554575939 81963.6557923697 78743.88669290571 0.8685073293900656 0.692009725011824 0.9024701125763179 0.8132023397527318 0.9476137357229524 0.9411752694003733 1.0335978641679828 0.9370264619209725 1.0408891310130628 1.0 16.264880303301084 -6.307737424325386 0.9925737976684988 1.0008744783126131 0.790757229274571 0.6577258806901944 0.05900179628111195 0.3107691135936779 0.6498644374294705 0.025924060781499995 0.03844260560251517 4.923371141285588e-07 6.307737424325386 -0.21011724903804208 KPGDLSDELR ddPTM_PC-9_AZD4547_30min_R2 2 KPGDLSDELR 10 1 E9PPJ0;Q13435;H0YEX5 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 0 ; 110.54 0.0010914000000000002 6631800.0 35675.0 39448.0 46848.0 58520.0 50269.0 48719.0 46986.0 52067.0 42082.0 44683.0 False True 47018.90791390269 52198.7945523153 46226.76491006059 45029.118124987195 43290.01705610147 45672.5932283554 51167.66297605708 44021.241530632324 44306.36860789431 43118.66177044672 1.0904537845868207 1.2105847540030115 1.0720825510810297 1.0443069491514203 1.0039740399775623 1.0592303043054812 1.1866709418873267 1.0209324622593976 1.0275450765093463 1.0 15.396024782892658 -1.5228787452803376 0.23126902603968055 1.0273845389682537 1.6965027050313124 0.22226666703414322 0.06111171301033415 83.98230604833473 1.102292810499053 0.09425751403162419 21.309131596101384 0.029999999999999995 1.5228787452803376 0.6691181660630587 KPGDLSDELR ddPTM_PC-9_Lapatinib_30min_R1 2 KPGDLSDELR 10 1 E9PPJ0;Q13435;H0YEX5 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 0 ; 80.916 0.010757 7366400.0 59044.0 50511.0 60545.0 57196.0 56156.0 57493.0 49085.0 53316.0 59836.0 48487.0 False True 58202.02173265653 50394.04488288661 55567.22381045863 61402.38464026272 52853.014486943866 55034.15841272894 51626.38112525047 55793.25599962721 53096.63957898637 56867.91334513363 1.0234597738697768 0.8861595567441193 0.9771278835785469 1.0797369030864417 0.9293995748740914 0.9677541371832028 0.9078297072714433 0.9811025711637372 0.9336836267710535 1.0 15.795327247988398 KPGMFFNPEESELDLTYGNR ddPTM_PC-9_Lapatinib_30min_R1 1 KPGMFFNPEESELDLTYGNR 20 1 P11413;P11413-2;P11413-3 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 69.612 0.0042332 8009800.0 43601.0 36608.0 38750.0 33266.0 39465.0 35483.0 35266.0 27777.0 40923.0 25502.0 False True 42979.24174455584 36523.23642518881 35564.12457932567 35712.49261212288 37143.746291175295 33965.474804912934 37091.90092213675 29067.620824923946 36313.82080170567 29909.98672072099 1.4369528862004057 1.2211050698958117 1.1890384610130105 1.1939989457562026 1.241850979005715 1.135589765453904 1.240117599130871 0.9718366342431883 1.2141035414284633 1.0 14.86833964948668 -1.5228787452803376 0.1599111518464643 1.0046281644450736 2.31316530834727 0.541017736795584 0.08410068657012809 50.91059773388084 0.5270749688723392 0.24347286399771273 15.684314912626107 0.029999999999999995 1.5228787452803376 1.3085371439021964 KPGPPLS(ph)PEIR ddPTM_PC-9_AZD4547_30min_R2 2 KPGPPLSPEIR 11 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 KPGPPLS(1)PEIR;KPGPPLS(1)PEIR 78.508 0.0083953 75127000.0 66893.0 60552.0 71503.0 85734.0 73183.0 82963.0 67793.0 83382.0 77661.0 65993.0 True False 88163.58253916442 80124.24984110198 70554.82350076972 65969.35087709593 63022.80368053221 77775.31049496199 73826.44566755703 70497.2278277448 81766.0019119262 63682.6051567059 1.3844217321546028 1.2581810942554499 1.1079135868759316 1.0359084826188087 0.9896392197751632 1.221295992894413 1.1592874614015845 1.1070091692114346 1.2839613221023527 1.0 15.958611735057003 -5.010005842803561 2.625300482112407 1.1153308740586572 1.3872605722610325 0.49688615704006256 0.08813581229472064 0.2787784544565133 3.4145682741945844 0.024002486455523258 0.13372190815087462 9.772240737321092e-06 5.010005842803561 0.27192969820237534 KPGPPLS(ph)PEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KPGPPLSPEIR 11 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 KPGPPLS(1)PEIR;KPGPPLS(1)PEIR 55.213 0.039327 40233700.0 63709.0 82215.0 78193.0 78836.0 76419.0 86766.0 88198.0 73768.0 75356.0 54267.0 True False 74493.67538989308 90376.76185999399 80057.41766860384 74419.07450976054 61445.245528381594 82215.83821718654 79843.2469417767 71831.66816365664 76457.93894045398 64105.177522664395 1.16205395989358 1.4098200075655554 1.2488448010349793 1.1608902336078808 0.9585067525420644 1.28251478888923 1.2455038739039153 1.1205283401369655 1.1926952220578793 1.0 15.968153261894548 -14.522878742359785 0.03636615907208276 0.07026885127903898 1.774732440417581 0.24843650815079654 0.10902857481730903 1534.5629718778262 4.165907301934673 167.1326810382987 55.81319227572092 3.0000000201744643e-15 14.522878742359785 1.704463589138542 KPGPPLS(ph)PEIR ddPTM_PC-9_Lapatinib_30min_R1 3 KPGPPLSPEIR 11 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 KPGPPLS(1)PEIR;KPGPPLS(1)PEIR;KPGPPLS(1)PEIR 56.793 0.036248 86087400.0 138761.0 123937.0 134178.0 118521.0 128704.0 146116.0 133167.0 142285.0 128034.0 113667.3 True False 136782.2426943488 123650.03149116664 123146.4027820584 127237.42971446595 121133.88376179969 139866.9592930322 140061.7356688647 148896.08053693 113613.46266220896 133314.54135284328 1.0260114261078808 0.9275059587378574 0.92372821098433 0.9544152380024843 0.9086321907014999 1.0491500617539287 1.0506110904898487 1.116878016651215 0.8522210818811465 1.0 17.02447462615747 -6.766642882869385 24.999983725997197 1.0233793702174292 0.945918247522674 0.1747384855596561 0.06978411952137345 198.00018234110274 951275.633394887 0.023582674515901986 0.021424895232253834 1.7114220262828042e-07 6.766642882869385 -0.07746112269475525 KPGPSGPSES(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPGPSGPSESPK 12 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 KPGPS(0.007)GPS(0.014)ES(0.979)PK 70.27199999999999 0.039691000000000004 0.0 7678.8 7696.0 3970.6 7872.3 5442.2 3493.4 7367.5 6855.7 4633.3 5700.8 True False 8978.669176786814 8460.008018907893 4065.274162584353 7431.240553340958 4375.839977159582 3310.1999542207723 6669.597063919129 6675.745139214588 4701.053247157576 6734.309912492032 1.3332723461585179 1.2562546317054284 0.603666034888495 1.1034895408594327 0.6497829820754867 0.49154256297002413 0.990390574622522 0.9913035227011445 0.6980749784676825 1.0 12.717314400084735 -5.170186961002973 6.445316466729115 0.8152613109339775 1.3082698567906434 0.49739701287554994 0.19275006694164426 0.195319799274723 11.451878101674094 0.049390061784924666 0.13421279307298029 6.757919886240219e-06 5.170186961002973 0.493008545856666 KPGPSGPSES(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 KPGPSGPSESPK 12 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 KPGPS(0.087)GPS(0.315)ES(0.598)PK;KPGPS(0.001)GPS(0.067)ES(0.931)PK 77.13 0.008206200000000002 68841000.0 290899.0 278011.0 216376.0 273762.0 265117.0 225677.0 244524.0 224791.0 211162.0 232470.0 True False 286750.7269156574 277367.2826104455 198586.40051551387 293895.37072326016 249523.33930007677 216025.32078878148 257184.25625487923 235235.61049989169 187378.71192556186 272652.1297531961 1.0517091033736774 1.0172936586320362 0.7283508135266491 1.0779133505734704 0.9151710625768614 0.7923111438165804 0.9432688330279381 0.8627682854075861 0.6872446296134804 1.0 18.05670189918567 -1.5228787961607326 0.5794595973147202 0.8664049317983088 11.556709388618437 0.1904717762081849 0.11650208035042484 256.7244110259871 2.1350339457087855 0.053937068065960006 3452.318226329479 0.029999996485307028 1.5228787961607326 10.690304456820128 KPIDSLRDS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 KPIDSLRDSR 10 2 Q9UQ35;Q9UQ35-2;I3L4U6 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 KPIDS(0.075)LRDS(0.925)R 74.53699999999999 0.0082292 22067000.0 48861.0 57524.0 54111.0 43772.0 44121.0 68987.0 62393.0 75319.0 69914.0 50925.0 True False 64397.78162806441 76117.50805686941 53393.452784500696 33681.041670658575 37995.56073389667 64673.23198432963 67945.85612874318 63680.1792084371 73609.51130774006 49142.131250363615 1.3104393315783982 1.5489256595135197 1.0865107276784138 0.6853801577930009 0.7731769006989402 1.316044508831739 1.3826395884741045 1.2958367410645404 1.497890088094122 1.0 15.584672807002377 -6.939276187166553 24.999542093933815 1.3231219155363967 1.0811662150454668 0.14839974667362787 0.25732006669490043 144.39877829664792 59446.87718770998 0.10147960915742793 0.0894965931878469 1.1500687764781601e-07 6.939276187166553 -0.24195570049092985 KPIDSLRDS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 KPIDSLRDSR 10 2 Q9UQ35;Q9UQ35-2;I3L4U6 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 KPIDS(0.015)LRDS(0.985)R 96.37100000000001 0.015623 49346000.0 81462.0 80680.0 59895.0 66555.0 68561.0 60443.0 53869.0 67696.0 64069.0 45867.0 True False 80300.33694169899 80493.19041696454 54970.66430138607 71449.67672097165 64528.376776112294 57857.993789514796 56658.0732369587 70841.40329639809 56852.874543520236 53795.04983606421 1.4927086634626674 1.4962936304039243 1.0218535807458946 1.3281831123627248 1.1995225763849457 1.0755263535554305 1.0532209452285908 1.3168758744955378 1.056842120544074 1.0 15.715185803157894 -5.248333842956595 24.738661774041677 1.147478664340416 1.4945012324164006 0.6276285544328868 0.11129814727415996 429.20986884176205 810193.9610260318 0.027561992676756613 0.07193330317605146 5.645028736028287e-06 5.248333842956595 0.34702256807598464 KPIET(ph)GSPK ddPTM_PC-9_Lapatinib_30min_R1 1 KPIETGSPK 9 1 Q5T757;Q05519-2;Q05519 Q5T757 SRSF11 Serine/arginine-rich splicing factor 11 1 KPIET(0.993)GS(0.007)PK 103.21 0.0099834 192620000.0 145630.0 145940.0 110170.0 130460.0 134250.0 104950.0 132060.0 128870.0 116510.0 128460.0 True False 143553.28949472902 145602.08489652668 101112.247868498 140054.46360180184 126353.67894565535 100461.53315039909 138897.4206254572 134857.7706630648 103387.41689530881 150664.13983780958 0.9528032991079668 0.9664017267364867 0.6711102454595078 0.9295806138910753 0.8386446773709755 0.6667912700297911 0.9219009963152526 0.8950887106131532 0.6862111780985555 1.0 17.200976550732022 KPIETGS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 KPIETGSPK 9 1 Q5T757;Q05519-2;Q05519 Q5T757 SRSF11 Serine/arginine-rich splicing factor 11 1 KPIET(0.16)GS(0.84)PK;KPIET(0.137)GS(0.863)PK;KPIET(0.124)GS(0.876)PK;KPIET(0.186)GS(0.814)PK 87.21600000000001 0.0091989 1765219000.0 1076383.0 1003830.0 726801.0 1007615.0 1054977.0 928270.0 1073812.0 828317.0 859103.0 1055634.0 True False 1418650.4038427535 1328298.4165344418 717163.1438566635 775324.9292465658 908511.6537785655 870225.1301563135 1169379.187750519 700319.6404810867 904513.4306864635 1018676.5749699811 1.3926406464039471 1.3039451865019913 0.7040145630891701 0.7611100012478578 0.8918548596303375 0.8542702870947609 1.1479396076080173 0.6874798711276188 0.8879299405830728 1.0 19.958264644624457 -5.181927564410916 5.992178954506139 0.8628883594805093 1.3627074319872725 0.6853377495432933 0.13067430052696463 0.1253463928094098 7.4266916226596 0.0335151790187322 0.09158642670368244 6.577675366673076e-06 5.181927564410916 0.49981907250676316 KPIETGS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 KPIETGSPK 9 1 Q5T757;Q05519-2;Q05519 Q5T757 SRSF11 Serine/arginine-rich splicing factor 11 1 KPIET(0.008)GS(0.992)PK;KPIET(0.081)GS(0.919)PK;KPIET(0.123)GS(0.877)PK;KPIET(0.112)GS(0.888)PK;KPIET(0.059)GS(0.941)PK;KPIET(0.002)GS(0.998)PK 118.61 0.0026259 884415000.0 529378.0 589447.0 405334.0 576995.0 551951.0 434710.0 544436.0 536832.0 428272.0 431282.0 True False 618991.2397079027 647963.4026404895 414998.69979775604 544667.8407930294 443800.1637634062 411913.04233678087 492863.0807047003 522740.7288205199 434534.66778897657 509470.0125735653 1.2149709000164617 1.2718381585744978 0.8145694340308832 1.0690871441906145 0.8711016405491057 0.8085128313166466 0.9674035145170257 1.0260480811813009 0.8529151020958895 1.0 18.95863770623594 -5.251906241452195 24.99296496618659 0.9275380871562382 1.2434045737373567 0.6854177605388263 0.08595341167885201 363.643660618444 953357.3206773648 0.021548947638418612 0.05544475073025514 5.598784589490542e-06 5.251906241452195 0.3158664865811185 KPIETGS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 KPIETGSPK 9 1 Q5T757;Q05519-2;Q05519 Q5T757 SRSF11 Serine/arginine-rich splicing factor 11 1 KPIET(0.237)GS(0.763)PK;KPIET(0.018)GS(0.982)PK;KPIET(0.154)GS(0.846)PK 89.44 0.0042835 856680000.0 1045297.0 1007037.0 712318.0 986108.0 841719.0 707210.0 837917.0 816499.0 644231.0 739177.0 True False 1030390.8730960062 1004705.2676986667 653753.963666995 1058629.6718798573 792210.7433032255 676964.2768870296 881300.2423006304 854436.5243161474 571670.9207268191 866942.7595585596 1.188533916149981 1.1589061176429394 0.7540912666481941 1.2211067688239339 0.913798211668107 0.7808638683731951 1.016561050408197 0.9855743241355631 0.6594102256738489 1.0 19.725577216180163 -1.5228787585106873 0.4724322909718286 0.8952455535982237 9.27977247379319 0.26940064143420905 0.1556906573405716 130.55103469101195 1.4913241876572547 0.09017959111010167 1070.3387197202755 0.02999999908607983 1.5228787585106873 8.384526920194967 KPISDNSFS(ph)SDEEQSTGPIK ddPTM_PC-9_AZD4547_30min_R2 2 KPISDNSFSSDEEQSTGPIK 20 1 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 KPIS(0.001)DNSFS(0.983)S(0.015)DEEQSTGPIK;KPIS(0.001)DNS(0.147)FS(0.819)S(0.033)DEEQSTGPIK 99.6 0.00016109 17348500.0 63642.0 64267.0 73018.0 104953.0 87377.0 76900.0 63686.0 76351.0 66732.0 71634.0 True False 83878.83216416526 85040.05094031747 72049.73361088634 80757.70735768604 75246.21178680661 72091.43084341916 69353.9306238702 64552.70732143796 70259.31728392182 69126.11546369278 1.213417412529438 1.2302159664241974 1.042293974246667 1.1682662451950239 1.0885352269841968 1.0428971794499846 1.0032956453382234 0.9338396478439915 1.0163932518502972 1.0 16.076943235344586 -5.899414135304033 0.4858736747674143 0.9686618299010443 1.265554827150471 0.7408473375836737 0.04784969058211643 0.8894054689198603 0.34016950764064213 0.03863561420350434 0.1359822109295888 1.260624852366337e-06 5.899414135304033 0.29689299724942675 KPISDNSFS(ph)SDEEQSTGPIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPISDNSFSSDEEQSTGPIK 20 1 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 KPIS(0.099)DNS(0.057)FS(0.597)S(0.247)DEEQSTGPIK 72.399 0.0015180999999999999 4719200.0 46558.0 43706.0 39880.0 51726.0 51661.0 42752.0 60092.0 48722.0 49482.0 39837.0 True False 54439.34983758408 48044.8428371087 40830.8904457422 48827.959917954664 41538.39790159149 40510.00985940529 54399.65073159526 47443.09912522618 50205.58063925308 47059.13275048152 1.1568285825885103 1.020946201704431 0.8676507206844863 1.0375873303244214 0.8826851553307994 0.8608320530299357 1.1559849821295025 1.0081592318494381 1.0668615782924593 1.0 15.522187113029034 -10.31634269606167 9.418460081795484 0.9999999998863498 1.0001897994957343 0.0 0.10292736229878544 0.0 0.0 0.10193080518787231 0.024721851730889456 4.826777770453501e-11 10.31634269606167 0.00018979960938447782 KPKVY(ph)Y(ph)NCSCIERK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPKVYYNCSCIERK 14 3 Q6ZQN7 Q6ZQN7 SLCO4C1 Solute carrier organic anion transporter family member 4C1 2 KPKVY(0.988)Y(0.988)NCS(0.023)CIERK 47.201 0.044804000000000004 0.0 6639.5 10171.0 8021.0 4092.4 8559.7 5431.1 7548.5 5694.5 6236.7 6113.5 True False 7763.436213897495 11180.709662202726 8212.251059811895 3863.116095739813 6882.488231320587 5146.2835550948785 6833.451433592606 5545.025408821482 6327.899938822794 7221.829155560629 1.0749958281580008 1.5481825201574946 1.13714280453293 0.5349221108014317 0.9530117762507913 0.7126011214392087 0.9462216962486599 0.7678145369240631 0.8762184486115222 1.0 12.818148575989788 -5.5471076159421475 9.773587164067752 0.8236848001082018 1.3194973263413097 0.5921583049332528 0.16628961688634608 0.17520460597295434 67.57975302401341 0.04114684834947858 0.07193776683075778 2.837215893801588e-06 5.5471076159421475 0.4958125262331079 KPLAAPGDGEGLGQTAQPS(ph)PPAR ddPTM_PC-9_AZD4547_30min_R2 2 KPLAAPGDGEGLGQTAQPSPPAR 23 1 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 KPLAAPGDGEGLGQTAQPS(1)PPAR;KPLAAPGDGEGLGQT(0.002)AQPS(0.998)PPAR 156.49 2.4122e-08 38549000.0 70347.0 70921.0 80309.0 100899.0 85959.0 93549.0 69258.0 100001.0 71590.0 88152.0 True False 92715.8826915015 93844.82631425555 79244.05018703155 77638.29442401041 74025.07661034497 87699.36624149537 75421.827829476 84548.14324437275 75374.1012461184 85065.82531138045 1.089931031082321 1.103202443175504 0.93156152775761 0.9126849018371147 0.8702093506925818 1.030958859453546 0.8866290023449142 0.9939143355735074 0.8860679476183786 1.0 16.376292033714577 -5.261742668467554 24.99879126625203 0.9368026477478273 1.0965667509236814 0.6010104468736241 0.05132671372987537 15.625619204502378 1288074.1297768569 0.012510000520402553 0.028917058911180595 5.47340181076639e-06 5.261742668467554 0.1597641031758541 KPLAAPGDGEGLGQTAQPS(ph)PPAR ddPTM_PC-9_Lapatinib_30min_R1 2 KPLAAPGDGEGLGQTAQPSPPAR 23 1 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 KPLAAPGDGEGLGQTAQPS(1)PPAR;KPLAAPGDGEGLGQT(0.002)AQPS(0.998)PPAR 142.96 3.8306999999999995e-07 28678000.0 82860.0 79387.0 91194.0 85411.0 99104.0 89252.0 78267.0 77782.0 102522.0 82886.0 True False 81678.40120533701 79203.18427902262 83696.38133902015 91692.40986274375 93274.8975659607 85434.90001657378 82319.28229662789 81396.03567715127 90974.89275547904 97212.7346613472 0.840202690417814 0.8147408315889567 0.8609610832427154 0.9432139748168364 0.9594925797622661 0.8788447348405228 0.8467952535580597 0.8372980758200519 0.9358330785817468 1.0 16.568857695740164 -14.522878745280336 0.19325892297440295 1.518265284286901 0.8587409529216986 0.40332282995015833 0.04608028386134472 169.22035721518316 1.6572998582908924 33.885653017275075 0.13737047327758395 3.0000000000000132e-15 14.522878745280336 -0.6595243313652025 KPLFLQQPS(ph)E ddPTM_PC-9_Lapatinib_30min_R1 1 KPLFLQQPSE 10 1 C9J2N3 C9J2N3 HIVEP1 1 KPLFLQQPS(1)E 63.966 0.019387 19414000.0 68357.0 60360.0 47625.0 47700.0 54464.0 52838.0 53874.0 53401.0 50355.0 46393.0 True False 67382.21664486162 60220.240128507365 43709.456337816344 51208.017122535355 51260.5346003439 50578.24191139389 56663.332112493496 55882.20540993498 44683.48963834246 54411.96823521326 1.2383712412971404 1.106746219291057 0.8033059224924219 0.9411167944003093 0.94208197686865 0.9295425905703897 1.0413762624345437 1.0270204740318554 0.8212070080829218 1.0 15.731636395262473 -5.027360798739476 5.200668021604464 0.9426718811317516 1.2134104436164708 0.6328277106407987 0.0744285430773545 0.10173964435440602 7.930132386899311 0.019197103466645216 0.061766570037618325 9.389429410173299e-06 5.027360798739476 0.27073856248471917 KPLPDHVSIVEPKDEILPTTPIS(ph)EQK ddPTM_PC-9_AZD4547_30min_R2 1 KPLPDHVSIVEPKDEILPTTPISEQK 26 2 P23396;P23396-2;E9PL09;E9PPU1;H0YEU2;E9PSF4 P23396 RPS3 40S ribosomal protein S3 1 KPLPDHVS(0.001)IVEPKDEILPT(0.326)T(0.326)PIS(0.347)EQK 59.81399999999999 0.00085181 5125400.0 11745.0 10683.0 32817.0 154750.0 66640.0 36799.0 16718.0 33104.0 22809.0 49267.0 True False 15479.66568882374 14136.07083254879 32381.8251377531 119074.77836366667 57388.18629013105 34497.9527127045 18205.86961294262 27988.537454242647 24014.637174503598 47542.17732570773 0.32559858549964515 0.29733747227653623 0.6811178401844694 2.5046134834737313 1.2071005056619324 0.7256283715481041 0.3829414351012078 0.5887096264543243 0.5051227883397347 1.0 15.536920356558646 -6.941319438531723 6.011701201181787 0.5804156018378378 1.0270548089632232 0.08400038204554428 0.5984308216407561 0.5287604322539156 38.629774203565866 0.23816499418896891 0.20870412207370428 1.1446706870615082e-07 6.941319438531723 0.4466392071253854 KPLSLAGDEETECQS(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPLSLAGDEETECQSSPK 18 1 F5H1K3;Q86TN4-2;Q86TN4;Q86TN4-4 F5H1K3 TRPT1 tRNA 2-phosphotransferase 1 1 KPLSLAGDEETECQS(0.611)S(0.389)PK 108.37 0.00012547 8548500.0 47349.0 48313.0 40719.0 53970.0 45838.0 37329.0 54072.0 44302.0 38033.0 35201.0 True False 55364.25051462196 53109.195350506394 41689.895387667435 50946.23587310079 36856.37295083625 35371.40152605118 48949.908712621 43139.11944184904 38589.160673633065 41582.66264903731 1.331426296144211 1.2771956379694684 1.0025787848059462 1.2251797414488141 0.8863398975171092 0.8506285858746007 1.177171099546081 1.037430426376214 0.9280108154528304 1.0 15.343694520323218 -5.059181949245516 1.0160440358139557 0.997994998774255 1.4429255869147517 0.5222604262096608 0.11130834211586316 1.0692579280171886 1.2114203040006548 0.03882718533357688 0.4690741033028008 8.726057104750164e-06 5.059181949245516 0.4449305881404967 KPLSLAGDEETECQS(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 1 KPLSLAGDEETECQSSPK 18 1 F5H1K3;Q86TN4-2;Q86TN4;Q86TN4-4 F5H1K3 TRPT1 tRNA 2-phosphotransferase 1 1 KPLSLAGDEETECQS(0.5)S(0.5)PK 128.67 1.9435e-05 10339000.0 65057.0 76886.0 61199.0 66374.0 72445.0 55316.0 65292.0 66619.0 55629.0 53241.0 True False 64129.275250007384 76707.97519086182 56167.454454971594 71255.36537717337 68183.92753234998 52950.26362789405 68672.50028379043 69714.36194461622 49363.476220660385 62443.63591082679 1.026994573819945 1.228435437366353 0.8994904546426804 1.141114932495767 1.0919275685631225 0.8479689379957015 1.0997517886668038 1.1164366220470001 0.7905285382669637 1.0 15.930266923236196 -6.327853989000285 0.41820663742836434 0.963891088607915 1.1183673733881458 0.10740697599839866 0.1253343612190018 4.226684463949784 1.3522619309246224 0.1193166082447195 0.28464647744473953 4.7005211485695445e-07 6.327853989000285 0.1544762847802309 KPLSLAGDEETECQSS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 KPLSLAGDEETECQSSPK 18 1 F5H1K3;Q86TN4-2;Q86TN4;Q86TN4-4 F5H1K3 TRPT1 tRNA 2-phosphotransferase 1 1 KPLSLAGDEETECQS(0.179)S(0.821)PK;KPLSLAGDEETECQS(0.033)S(0.967)PK;KPLSLAGDEETECQS(0.047)S(0.953)PK;KPLSLAGDEETECQS(0.109)S(0.891)PK 172.57 1.7787e-08 48487000.0 256181.0 264720.0 220523.0 246884.0 257182.0 265562.0 269545.0 243534.0 257296.0 253337.0 True False 337641.2291041768 350285.56311825477 217598.72093283155 189968.70811977674 221476.71858446155 248956.36615916865 293533.98282214423 205901.41615458927 270896.14127980516 244467.74873978115 1.3811279027385013 1.4328497927598183 0.8900917280685977 0.777070632421069 0.9059547516028711 1.018360775368228 1.2007063685713024 0.8422436792419475 1.1081058449478962 1.0 17.899284625494964 -5.257711093216346 24.946608734198065 0.9632834794935324 1.4069888986472603 0.6862213852042128 0.11875682364822746 173.4326537067306 1160455.1555980442 0.03220248921636206 0.07862918615864621 5.524448212937757e-06 5.257711093216346 0.44370541915372785 KPLSLAGDEETECQSS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KPLSLAGDEETECQSSPK 18 1 F5H1K3;Q86TN4-2;Q86TN4;Q86TN4-4 F5H1K3 TRPT1 tRNA 2-phosphotransferase 1 1 KPLSLAGDEET(0.004)ECQS(0.397)S(0.598)PK;KPLSLAGDEETECQS(0.264)S(0.736)PK;KPLSLAGDEETECQS(0.225)S(0.775)PK 165.9 6.2248e-08 30177400.0 153734.0 154626.0 123321.0 164106.0 152199.0 128030.0 165232.0 136677.0 110254.0 147080.0 True False 179758.12981509388 169976.2473923664 126261.44033749684 154911.67285883013 122376.69851966301 121315.88141606616 149580.0287839141 133089.37357125207 111866.25616992448 173744.43971536067 1.0346122736910903 0.9783118681140671 0.7267078045452646 0.8916065061570685 0.7043488627328068 0.6982432451640677 0.8609198028378102 0.7660065196289887 0.6438551723047424 1.0 17.406607282929457 -5.164405664695744 4.645019113154003 0.7786048973093526 1.0203719468109762 0.4316506855021456 0.10116574409799542 0.18757016895727865 6.650666050485977 0.02473557217525429 0.07127468963623904 6.8484822628812615e-06 5.164405664695744 0.24176704950162364 KPLSLAGDEETECQSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 KPLSLAGDEETECQSSPK 18 1 F5H1K3;Q86TN4-2;Q86TN4;Q86TN4-4 F5H1K3 TRPT1 tRNA 2-phosphotransferase 1 1 KPLSLAGDEETECQS(0.286)S(0.714)PK 128.67 1.9435e-05 23879000.0 33399.0 35901.0 23265.0 34583.0 31100.0 29524.0 30766.0 29460.0 28453.0 24217.0 True False 32922.72413537354 35817.873440250856 21352.24150549707 37126.349185506086 29270.75914495252 28261.32734380549 32358.91294080585 30828.819149017534 25248.323516627097 28402.876182875843 1.1591334597030254 1.2610650136145554 0.7517633555143399 1.307133437700568 1.0305561646816574 0.9950163906585033 1.139282963192126 1.0854118769705547 0.8889354498488913 1.0 14.793749409443837 KPLTS(ph)SSAAPQRPISTQR ddPTM_PC-9_Lapatinib_30min_R1 1 KPLTSSSAAPQRPISTQR 18 2 Q15691 Q15691 MAPRE1 Microtubule-associated protein RP/EB family member 1 1 KPLT(0.364)S(0.521)S(0.057)S(0.057)AAPQRPISTQR 65.16 0.042808 21096000.0 10629.0 7754.9 8663.6 5736.6 17487.0 20756.0 22790.0 23703.0 24241.0 22039.0 True False 10477.42851088012 7736.944005509633 7951.312250463118 6158.4887007366115 16458.449040764786 19868.314264599194 23969.954687673595 24804.327912055756 21510.723310953406 25848.41178487843 0.4053412874290991 0.29931989902899253 0.3076131839989764 0.23825404639906683 0.6367296055842447 0.768647390406491 0.9273279490887811 0.9596074265021779 0.8321874276057992 1.0 14.657788018678778 -6.602480569178875 1.8362088931615246 0.9190391027456936 0.30831850193541144 0.9416120593342077 0.06880259891909273 0.07337765508384726 0.5055399583988377 0.026410001740650002 0.027125491470474532 2.4975801311844244e-07 6.602480569178875 -0.6107206008102821 down KPNAGGS(ph)PAPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPNAGGSPAPVR 12 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 KPNAGGS(1)PAPVR 60.657 0.027075 6960700.0 18743.0 31958.0 27489.0 28331.0 36124.0 24391.0 28648.0 27358.0 20164.0 17626.0 True False 21915.819708875773 35130.57903693585 28144.44201261303 26743.705920341283 29045.761518303763 23111.89302209849 25934.254046441165 26639.88148819705 20458.860353459822 20821.454272660765 1.0525595101035736 1.6872298436456201 1.3517039513213822 1.2844302597756883 1.3949919702026663 1.1100037835707348 1.245554403012746 1.2794438438037474 0.9825855622545521 1.0 14.345783216615418 -7.699441491480062 0.5078131960103778 0.9866855785717071 1.3915452087461253 0.34588554439844266 0.1649496251329853 0.9602500774855818 0.5651422769699769 0.16171256839449585 0.11183866877796027 1.997829899647398e-08 7.699441491480062 0.4048596301744182 KPNEGADGQWK ddPTM_PC-9_AZD4547_30min_R2 2 KPNEGADGQWK 11 1 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 ; 111.94 0.0011074000000000001 10535100.0 58409.0 48543.0 69158.0 81865.0 72295.0 76793.0 56520.0 75676.0 73713.0 58822.0 False True 76981.84701732706 64233.57543989662 68240.9197329655 62992.28905164185 62258.0871525365 71991.12157033406 61550.17050625174 63982.01306148107 77609.31869192794 56762.6596840234 1.356205777633683 1.1316167317997612 1.2022149792281986 1.1097487221757487 1.0968141292022626 1.2682830926366353 1.0843426091884811 1.1271849032030057 1.3672600812567652 1.0 15.792654569776898 -11.859090687890696 2.1875738012802914 6.870808920036851e-05 1.183859357632236 0.24809999766831892 0.09985867920515093 4236283.938594121 753688.0876300615 20780675.480926696 0.023995194484079437 1.383277497527752e-12 11.859090687890696 1.1837906495430357 KPNEGADGQWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPNEGADGQWK 11 1 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 83.226 0.008269799999999999 4438300.0 30662.0 28507.0 35455.0 31441.0 33584.0 26854.0 32509.0 34494.0 23659.0 27299.0 False True 35852.47099789515 31336.98656380034 36300.38166383627 29679.462703097324 27003.45628476121 25445.728966234794 29429.512175221847 33588.56904941406 24004.96811656943 32248.092601234894 1.1117702817723314 0.9717469790011808 1.1256598060762886 0.9203478503395514 0.8373659992444685 0.7890615200373242 0.9125969879562702 1.0415676196652894 0.7443841226023457 1.0 14.976926210593282 -5.885045569792213 5.838795660792107 0.8854302396649413 1.0588641212602243 0.4396959310202506 0.09207896893449624 0.1985106796546803 9.37865482102391 0.025688207577586206 0.03860553204456819 1.3030300465196814e-06 5.885045569792213 0.17343388159528306 KPNEGADGQWK ddPTM_PC-9_Lapatinib_30min_R1 1 KPNEGADGQWK 11 1 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 100.38 0.0026406999999999997 6082500.0 46349.0 49059.0 50367.0 57689.0 57179.0 51546.0 60913.0 53227.0 51830.0 49560.0 False True 45688.054760634404 48945.406899675974 46226.01968224244 61931.64150486253 53815.843638239254 49341.497739594786 64066.777090401934 55700.12073471677 45992.3596059039 58126.37996545101 0.786012388657101 0.8420515251210897 0.7952674794081126 1.0654653109598995 0.925841995841237 0.8488658294034868 1.1021979543278244 0.9582588966975693 0.7912476165424495 1.0 15.826905441765957 -5.733781759034939 24.999001108632942 0.9546165855597625 0.8112044541554531 0.37535108849693755 0.08756793997228955 242.55830719815157 219240.2933414537 0.023842686986770112 0.04128464764380408 1.8459428063577065e-06 5.733781759034939 -0.14341213140430942 KPNIFYSGPAS(ph)PARPR ddPTM_PC-9_Lapatinib_30min_R1 2 KPNIFYSGPASPARPR 16 2 Q6PL18;Q6PL18-2 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 KPNIFYS(0.011)GPAS(0.988)PARPR;KPNIFYS(0.002)GPAS(0.998)PARPR 78.55199999999999 0.0030919 55766000.0 105021.0 79675.0 93551.0 75336.0 79527.0 72392.0 73749.0 66216.0 80859.0 68175.0 True False 103523.38128150735 79490.51743271752 85859.59789730328 80876.46075352881 74849.37821609773 69295.96291399426 77567.36236337163 69292.63709339239 71751.80793698214 79958.9579125226 1.2947064842286327 0.9941414884331338 1.073795859011021 1.0114746723188912 0.9360974701294269 0.8666441474863396 0.9700897108768296 0.8666025533899595 0.8973579672646644 1.0 16.28697204942798 -1.5228787452973431 0.5729427758693013 0.9171535576204185 18.85632229729807 0.7526558159891695 0.059423404665342495 72.23618873384603 0.6140116947580052 0.027797770040144214 1608.1942268536736 0.029999999998825296 1.5228787452973431 17.93916873967765 KPPAPPS(ph)PVQSQS(ph)PSTNWSPAVPVKK ddPTM_PC-9_AZD4547_30min_R2 1 KPPAPPSPVQSQSPSTNWSPAVPVKK 26 2 A9Z1X7;Q8IYB3;Q8IYB3-2 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 2 KPPAPPS(0.997)PVQS(0.302)QS(0.31)PS(0.183)T(0.208)NWSPAVPVKK 70.109 0.0018969000000000002 10826000.0 52291.0 45553.0 72503.0 90631.0 77122.0 74991.0 59934.0 80864.0 51504.0 63253.0 True False 68918.45027963245 60277.1164125334 71541.56284738138 69737.42318499179 66414.9415226214 70301.80091519936 65268.00989245743 68368.32686986114 54226.396292500045 61038.53172271483 1.1290974460643062 0.9875256614356259 1.1720721457124756 1.1425147561182203 1.0880822268846582 1.1517610094975024 1.069291938229383 1.1200847225559751 0.888396145222482 1.0 15.897432638218694 -8.252199045957893 24.98803128757862 0.9441980705726577 1.1064179198334871 0.5836654085087574 0.0551799038939548 387.70862400410164 1048462.1330352955 0.03717628484685562 0.013613994269763546 5.5950111202984324e-09 8.252199045957893 0.16221984926082944 KPPAPPS(ph)PVQSQSPSTNWSPAVPVK ddPTM_PC-9_AZD4547_30min_R2 2 KPPAPPSPVQSQSPSTNWSPAVPVK 25 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 KPPAPPS(0.571)PVQS(0.228)QS(0.076)PS(0.034)T(0.038)NWS(0.052)PAVPVK;KPPAPPS(0.761)PVQS(0.103)QS(0.103)PS(0.015)T(0.015)NWS(0.003)PAVPVK 49.902 0.012095 19775100.0 139110.0 145419.0 176556.0 188334.0 191230.0 180557.0 170046.0 212985.0 168063.0 176707.0 True False 183344.0863322496 192422.8479264635 174214.7520803591 144916.50603129438 164681.0153700745 169266.74224701204 185179.76457724886 180073.06215840593 176946.4670725852 170520.54171542474 1.0752023450536863 1.128443799149962 1.0216643128609073 0.8498477929605691 0.9657547044678313 0.9926472232858308 1.085967489396605 1.056019763641867 1.0376841716107401 1.0 17.379586018060984 -10.325546383518876 15.160121210816339 0.999993324884346 1.0217658792072815 0.008769886988963194 0.07302409768400409 0.0 0.0 0.07934182735118185 0.019243219688143715 4.725563642386964e-11 10.325546383518876 0.021772554322935456 KPPAPPS(ph)PVQSQSPSTNWSPAVPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPPAPPSPVQSQSPSTNWSPAVPVK 25 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 KPPAPPS(0.991)PVQS(0.009)QSPSTNWSPAVPVK 89.024 3.2574e-06 5741000.0 30454.0 43308.0 40545.0 42417.0 43442.0 33422.0 41918.0 36189.0 34453.0 28293.0 True False 35609.26070608243 47607.33202739907 41511.74656776877 40040.51300776946 34929.85195100632 31669.291483931596 37947.22357996093 35239.07709541499 34956.80994632766 33422.29693273522 1.065434275141192 1.424418319399539 1.2420375132000698 1.1980179904557093 1.0451062660745658 0.9475498212366531 1.1353864653986068 1.0543583275062207 1.0459128532273159 1.0 15.028523264941217 -6.140892425650131 2.9734639517264267 1.0402509845580983 1.2588489868311052 0.5191442254753116 0.09205654854080232 0.20441077625685736 3.465665134351301 0.027931519588178823 0.03777210580137516 7.229488552025239e-07 6.140892425650131 0.21859800227300696 KPPAPPS(ph)PVQSQSPSTNWSPAVPVK ddPTM_PC-9_Lapatinib_30min_R1 1 KPPAPPSPVQSQSPSTNWSPAVPVK 25 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 KPPAPPS(0.939)PVQS(0.011)QS(0.013)PS(0.016)T(0.018)NWS(0.003)PAVPVK 50.631 0.010574 8048200.0 41228.0 45454.0 55370.0 46673.0 58000.0 56499.0 60772.0 60016.0 54618.0 51819.0 True False 40640.08115971078 45348.754055685415 50817.692334380954 50105.4881165638 54588.55403238737 54082.66947560172 63918.47680032026 62804.56245917975 48466.345686962326 60775.84510552269 0.6686880468572509 0.746164104784527 0.8361494973232904 0.8244309565678211 0.8981948986082782 0.88987112201731 1.0517085643044723 1.033380323221087 0.7974606622550806 1.0 15.891210429030433 -5.150515821816744 0.5236297001294982 0.9739546645682294 0.5433334669976261 0.6543624609360453 0.07004148273686904 1.914766137054144 0.529978993141206 0.04578086292987662 0.4821716626523997 7.071054395976528e-06 5.150515821816744 -0.43062119757060335 KPPAPPS(ph)PVQSQSPSTNWSPAVPVKK ddPTM_PC-9_AZD4547_30min_R2 2 KPPAPPSPVQSQSPSTNWSPAVPVKK 26 2 A9Z1X7;Q8IYB3;Q8IYB3-2 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 KPPAPPS(0.997)PVQS(0.003)QSPSTNWSPAVPVKK;KPPAPPS(0.3)PVQS(0.058)QS(0.286)PS(0.286)T(0.07)NWSPAVPVKK 98.95700000000001 9.895e-10 25199000.0 68937.0 47832.0 67904.0 91241.0 93337.0 74278.0 67326.0 74271.0 68181.0 75738.0 True False 90857.53202132347 63292.75859425939 67003.54859231462 70206.79710939784 80378.76866389526 69633.38491791247 73317.88357225577 62794.12352779298 71784.90846572981 73086.4356728532 1.2431517720745966 0.8659987042953919 0.9167713266553786 0.9605995485079463 1.0997768316912282 0.9527538766509678 1.0031667695554147 0.8591761651761172 0.9821919458085322 1.0 16.15731605654321 KPPAPPS(ph)PVQSQSPSTNWSPAVPVKK ddPTM_PC-9_Lapatinib_30min_R1 1 KPPAPPSPVQSQSPSTNWSPAVPVKK 26 2 A9Z1X7;Q8IYB3;Q8IYB3-2 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 KPPAPPS(0.981)PVQS(0.003)QS(0.011)PS(0.003)T(0.003)NWSPAVPVKK 61.963 0.00051176 8576900.0 40855.0 26594.0 33445.0 33641.0 36630.0 35483.0 29648.0 26824.0 34377.0 26340.0 True False 40272.400208110565 26532.423226930507 30695.281201433467 36115.071363086194 34475.49541735083 33965.474804912934 31183.02837122187 28070.3409658264 30505.100254141576 30892.83390415615 1.3036162474784336 0.8588536522497855 0.9936052256217225 1.169043651842749 1.1159706333290675 1.0994612831664954 1.0093935851908582 0.9086359980089095 0.9874490747201277 1.0 14.914984599881869 -7.466259649613881 4.412720321983124 0.9600974795307602 1.0792647690656036 0.20664615065374392 0.11008844674475977 0.3709883539255053 14.859893869667255 0.049895195810699705 0.03156424186665451 3.4177504596823885e-08 7.466259649613881 0.11916728953484346 KPPAPPSPVQS(ph)QSPSTNWSPAVPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPPAPPSPVQSQSPSTNWSPAVPVK 25 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 KPPAPPS(0.012)PVQS(0.626)QS(0.33)PS(0.023)T(0.009)NWSPAVPVK 67.895 0.00030464 6430000.0 55332.0 66511.0 59844.0 69882.0 84152.0 56293.0 64906.0 63225.0 59589.0 55980.0 True False 64698.614743184895 73113.77252411428 61270.907919633806 65966.73810050091 67663.01969018641 53340.89598183715 58757.63380125347 61565.4107424249 60460.3763936876 66128.73086256383 0.9783737552388362 1.1056279406914304 0.926539903615781 0.9975503421893944 1.023201546553363 0.8066221033743444 0.8885341217778729 0.9309933812335983 0.9142830295555371 1.0 16.012989593299075 -6.726576114063239 24.997617722340557 0.9025514792877575 1.006866654192597 0.39146837903302356 0.061002781464019676 178.69834765662424 128129.61051677087 0.019828196165377777 0.019827395480054688 1.8768254587946633e-07 6.726576114063239 0.10431517490483955 KPPAPPSPVQSQS(ph)PSTNWSPAVPVKK ddPTM_PC-9_Lapatinib_30min_R1 1 KPPAPPSPVQSQSPSTNWSPAVPVKK 26 2 A9Z1X7;Q8IYB3;Q8IYB3-2 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 KPPAPPS(0.141)PVQS(0.04)QS(0.536)PS(0.141)T(0.141)NWS(0.001)PAVPVKK 48.5 0.0092194 8125300.0 55533.0 40610.0 45164.0 46402.0 53504.0 41826.0 40132.0 41677.0 47577.0 34964.0 True False 54741.08923649506 40515.970040070984 41450.79025808163 49814.55787253428 50356.999912911284 40037.19948116811 42209.83859261591 43613.465569368724 42218.37725197934 41007.48081339848 1.3349049527229033 0.9880141192880373 1.0108104530171067 1.214767571292949 1.2279954514167086 0.9763389188268949 1.029320449717179 1.0635490087242518 1.029528671709705 1.0 15.323599497765901 -6.773401073993369 24.989322426671535 1.0243175358524332 1.1412816639660992 0.3197608289686942 0.09767688259470729 334.32320306622137 698434.6887244479 0.035524355818833196 0.031566844439063546 1.6849962008465835e-07 6.773401073993369 0.11696412811366597 KPPLS(ph)PAQTNPVVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPPLSPAQTNPVVQR 15 1 Q8IY33-4;Q8IY33-2;Q8IY33 Q8IY33-4 MICALL2 MICAL-like protein 2 1 KPPLS(0.988)PAQT(0.012)NPVVQR 55.336999999999996 0.03246 23198000.0 23863.0 24191.0 69488.0 48478.0 77019.0 67348.0 49013.0 63375.0 60931.0 42706.0 True False 27902.53458426628 26592.522607250623 71144.85745470738 45761.93482779655 61927.679835517585 63816.15232062194 44370.133816609174 61711.47340136304 61822.000604873014 50448.25973948999 0.5530921131541962 0.5271246767395322 1.4102539477494893 0.9071063117758039 1.2275483863131498 1.2649822342765136 0.8795176294629848 1.22326267982355 1.225453582028715 1.0 15.622516882607325 -5.245378038296677 24.81337536834622 1.1398854082591832 0.5401082358849297 0.6966596848928535 0.1589306347848056 380.5117935558773 587855.1049342176 0.03845274860586853 0.10103883663514326 5.683579795305178e-06 5.245378038296677 -0.5997771723742534 KPPLS(ph)PAQTNPVVQR ddPTM_PC-9_Lapatinib_30min_R1 2 KPPLSPAQTNPVVQR 15 1 Q8IY33-4;Q8IY33-2;Q8IY33 Q8IY33-4 MICALL2 MICAL-like protein 2 1 KPPLS(0.992)PAQT(0.008)NPVVQR;KPPLS(1)PAQTNPVVQR 105.2 0.00049116 54562000.0 229010.0 208020.0 260550.0 212880.0 212415.0 240350.0 194997.0 207986.0 273110.0 160103.0 True False 225744.2754047098 207538.3424707111 239128.58475208475 228535.90534686204 199921.1673239579 230070.7907832153 205092.9905323512 217649.7888502222 242349.4758242026 187776.5902261627 1.2021960518764234 1.1052407662784103 1.273473889711558 1.2170628142283755 1.0646756716754096 1.2252368120334514 1.0922180996328255 1.1590890461269931 1.290626672538419 1.0 17.518657690411693 KPQS(ph)SSTEPAR ddPTM_PC-9_Lapatinib_30min_R1 1 KPQSSSTEPAR 11 1 Q7Z4V5-2;Q7Z4V5;Q7Z4V5-4;Q7Z4V5-3;A0A087WT54 Q7Z4V5-2 HDGFRP2 Hepatoma-derived growth factor-related protein 2 1 KPQS(0.332)S(0.332)S(0.332)T(0.004)EPAR 72.705 0.039029 1005100.0 3433.1 3240.8 3353.0 3633.3 3553.6 4652.2 3344.7 2710.1 3160.5 2980.1 True False 3384.1433644465674 3233.296126714158 3077.329282954293 3900.505002333495 3344.584234646407 4453.236250807882 3517.87220025721 2836.0211397064622 2804.5312084595616 3495.2063142663524 0.9682242077194527 0.925065886244495 0.8804428140317742 1.1159584446883262 0.9569060976443214 1.2740982506901375 1.006484849234319 0.8114030717244645 0.8023936089301315 1.0 11.771161901860507 -7.721938177164949 8.613716295149585 0.8553005318974064 1.0208247630923115 0.2483315877640908 0.11609288295814621 0.3453331607745837 68.935302107659 0.05749119052399649 0.032774270745295396 1.8969759409527926e-08 7.721938177164949 0.1655242311949051 KPRPLS(ph)MDLTAR ddPTM_PC-9_AZD4547_30min_R2 2 KPRPLSMDLTAR 12 2 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 KPRPLS(0.983)MDLT(0.017)AR;KPRPLS(0.99)MDLT(0.01)AR 65.528 0.01324 14711700.0 51335.0 50241.0 75338.0 94583.0 88559.0 82704.0 55046.0 79324.0 52894.0 59918.0 True False 67658.46216566768 66480.42073369682 74338.9688950252 72778.350642783 76264.11148961168 77532.50580590541 59944.98736176813 67066.29848418156 55689.86885475877 57820.28905761977 1.1701508807443672 1.149776692874139 1.2856900251907084 1.2586991837805765 1.318985303127974 1.3409221411647008 1.0367465873792334 1.1599094293241574 0.9631544525704816 1.0 15.819288200764138 -7.274275065799456 24.833770080180642 1.053278384461874 1.2539010855777817 0.672165017834558 0.07300860436606023 492.12207471436477 952126.1942615226 0.03212230893740528 0.021810554072091533 5.3177134860217065e-08 7.274275065799456 0.20062270111590763 KPRPLS(ph)MDLTAR ddPTM_PC-9_Lapatinib_30min_R1 2 KPRPLSMDLTAR 12 2 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 KPRPLS(0.997)MDLT(0.003)AR;KPRPLS(1)MDLTAR 65.528 0.01324 14962600.0 124210.0 94346.0 105131.0 103646.0 106176.0 111015.0 107298.0 104062.0 117395.0 95530.0 True False 122438.74262267565 94127.54763360093 96487.53499739555 111268.47259292012 99930.93643004762 106267.14723860461 112853.36542685384 108897.10041700794 104172.73887584577 112042.23321427652 1.0927909870246535 0.8401077427079267 0.8611711158315346 0.9930940271435271 0.8919041825856281 0.9484561686250284 1.007239522002619 0.9719290422277318 0.9297631427661689 1.0 16.773683118897722 -7.005361997188514 24.44739654724316 0.9753157078651151 0.9285968690131632 0.0684353674062147 0.06968317772619861 463.49138363706766 2113243.2021458503 0.024599571639590062 0.021052862038906623 9.877294499719905e-08 7.005361997188514 -0.04671883885195194 KPRPS(ph)EGDEDCLPASK ddPTM_PC-9_AZD4547_30min_R2 3 KPRPSEGDEDCLPASK 16 2 Q5VU10;P78346;P78346-2 Q5VU10 RPP30 Ribonuclease P protein subunit p30 1 KPRPS(1)EGDEDCLPASK;KPRPS(1)EGDEDCLPASK;KPRPS(1)EGDEDCLPASK 96.633 0.006462600000000001 97972000.0 50739.0 48928.0 56687.0 73943.0 56665.0 59212.0 55854.0 63944.0 54668.0 56903.0 True False 66872.94656323791 64743.01916081129 55935.29334137216 56896.583757961846 48798.04285909783 55509.464279590735 60824.8977964647 54062.92408694094 57557.63887306603 54910.84328992524 1.217845921800065 1.1790570911281197 1.0186566075126164 1.0361629934829455 0.8886777171031182 1.0109016899723215 1.107702853429398 0.9845582556707908 1.0482016924993467 1.0 15.744803447102818 -5.219506579993508 3.2009908859469767 1.0096217148696331 1.2125747674356737 0.673868136797322 0.05223555411826923 0.1496329721392909 3.073511581199714 0.01452559269396527 0.04483382187895065 6.032445681019608e-06 5.219506579993508 0.20295305256604057 KPRPS(ph)EGDEDCLPASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPRPSEGDEDCLPASK 16 2 Q5VU10;P78346;P78346-2 Q5VU10 RPP30 Ribonuclease P protein subunit p30 1 KPRPS(1)EGDEDCLPASK 73.44800000000001 0.040803 13606000.0 28048.0 44350.0 44629.0 37353.0 54609.0 49360.0 78695.0 54390.0 48424.0 43254.0 True False 32795.97242674855 48752.774901060955 45693.124616425004 35260.23251005991 43908.75846398657 46771.47470668616 71240.43989753873 52962.32013096857 49132.10939079242 51095.607801524406 0.6418550211623102 0.9541480569217624 0.8942671705543697 0.6900834343144451 0.8593450661071611 0.9153717260466909 1.394257607704068 1.0365337141441826 0.9615720705709385 1.0 15.640911661410977 -7.014593167087861 21.55185813227934 1.1088038992889035 0.821615339372189 0.48948344548072686 0.13932101612131936 95.14673873992147 140516.83701915978 0.05201443589890833 0.041963286636191914 9.66956267962089e-08 7.014593167087861 -0.28718855991671455 KPS(ph)EDEVLNK ddPTM_PC-9_AZD4547_30min_R2 2 KPSEDEVLNK 10 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 KPS(1)EDEVLNK;KPS(1)EDEVLNK 98.25299999999999 0.0022145 73880000.0 252104.0 208079.0 241490.0 279700.0 290530.0 307470.0 264340.0 316410.0 269410.0 284650.0 True False 332267.82791104546 275336.467543379 238287.68481323688 215219.48632192262 250194.92441284235 288243.85229422676 287865.7479055665 267516.1048784711 283650.4625885842 274684.4901407168 1.2096344709554936 1.0023735501131796 0.8674959576027231 0.783515247663488 0.9108447451280238 1.0493634065271167 1.0479869022022217 0.9739032034223214 1.0326409854567118 1.0 18.067415926427635 -6.763090628330309 24.999358315244933 1.0208483526419825 0.943054257760012 0.08412244578779082 0.10540881373907304 114.18787071714922 1728743.3730607112 0.03958860498107526 0.03675834267812965 1.7254777826762912e-07 6.763090628330309 -0.07779409488197053 KPS(ph)EDEVLNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 KPSEDEVLNK 10 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 KPS(1)EDEVLNK;KPS(1)EDEVLNK;KPS(1)EDEVLNK;KPS(1)EDEVLNK 138.89 0.00017638 81976000.0 190532.0 198714.0 199129.0 257093.0 302962.0 283411.0 345686.0 328665.0 285145.0 250248.0 True False 222785.30442146555 218441.0126649254 203876.9905609383 242688.9127167518 243598.77093091427 268548.4282434489 312940.1195300917 320037.8919993527 289314.70618365926 295615.9814379226 0.7536307859196341 0.7389350589315029 0.6896683649146728 0.8209600561386255 0.8240378945211676 0.9084367730634425 1.0586035234221838 1.0826136342245034 0.9786842537280531 1.0 18.17336474026051 -6.778633959353132 1.3576513816256572 1.039901417109712 0.7395359250881912 0.9019575868965628 0.04157532466715589 0.11888604867660015 0.4582967902259492 0.020248541619698936 0.018009088982242523 1.6648152316433618e-07 6.778633959353132 -0.30036549202152085 KPS(ph)EDEVLNK ddPTM_PC-9_Lapatinib_30min_R1 3 KPSEDEVLNK 10 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 KPS(1)EDEVLNK;KPS(1)EDEVLNK;KPS(1)EDEVLNK 136.01 0.00016824 171554000.0 182929.0 197694.0 212685.0 178547.0 239104.0 234738.0 284895.0 235159.0 255603.0 238231.0 True False 180320.39891493027 197236.25168928315 195198.8602878416 191677.94199533158 225040.3728165507 224698.80294100428 299645.4690980592 246085.34563013606 226814.29852108503 279408.91092714656 0.6453638086079053 0.7059053737219955 0.6986135826524803 0.6860122726912956 0.8054158762145851 0.8041934031216081 1.0724263163396002 0.8807354955629911 0.8117647277907499 1.0 18.092018506441896 -6.673819987408317 1.6717807670624336 0.9286712789598363 0.6855731395757617 0.7005931142021682 0.07253783699081319 0.21333023918270405 1.231719505875011 0.030305449836708482 0.02954937227429302 2.1192393658841554e-07 6.673819987408317 -0.24309813938407454 KPS(ph)GLNGEASK ddPTM_PC-9_AZD4547_30min_R2 2 KPSGLNGEASK 11 1 P16070;P16070-5;P16070-7;P16070-3;P16070-4;P16070-8;P16070-17;H0Y2P0;H0YD13;H0YE40;P16070-10;P16070-16;P16070-11;P16070-13;P16070-14;P16070-12;P16070-18;P16070-6;J3KN83 P16070 CD44 CD44 antigen 1 KPS(0.996)GLNGEAS(0.004)K;KPS(0.991)GLNGEAS(0.009)K 101.72 0.0053111 42076000.0 176067.0 279240.0 162799.0 97448.0 106216.0 74936.0 141256.0 166953.0 122826.0 80475.0 True False 232052.6435788952 369498.8691641792 160640.17888902285 74982.86915659183 91469.74182161737 70250.24007389409 153827.5103508684 141154.25004827717 129318.33160575124 77657.59474468375 2.988151311430888 4.75805193785601 2.0685701046647456 0.9655574500229415 1.1778595786071415 0.9046151932062414 1.9808430953419278 1.8176490079605543 1.6652374057027315 1.0 16.24483940351417 -5.431484072959544 4.942107706911748 1.3983892084662382 3.8445153405938375 0.7760185524624779 0.5319606819481765 0.09369294282467114 3.738616463522579 0.13999778534078375 0.2985631728432634 3.7026778411708335e-06 5.431484072959544 2.446126132127599 KPS(ph)GLNGEASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPSGLNGEASK 11 1 P16070;P16070-5;P16070-7;P16070-3;P16070-4;P16070-8;P16070-17;H0Y2P0;H0YD13;H0YE40;P16070-10;P16070-16;P16070-11;P16070-13;P16070-14;P16070-12;P16070-18;P16070-6;J3KN83 P16070 CD44 CD44 antigen 1 KPS(1)GLNGEASK 82.20200000000001 0.02087 13633000.0 74374.0 86336.0 50517.0 38139.0 71552.0 21527.0 26694.0 28910.0 33472.0 22736.0 True False 86964.04924654128 94906.86750525344 51721.516866789345 36002.19547830632 57531.89924032975 20398.086223882354 24165.351072176076 28151.14313267699 33961.46467719734 26857.856821923026 3.237937033589214 3.533672404857883 1.9257499661913113 1.34047164362419 2.142088239645715 0.7594830205227764 0.8997497913702048 1.0481529974386603 1.2644890060429512 1.0 14.713056566081578 -5.380160392201734 0.9944866278689389 1.0848954548465453 3.8672809814012132 0.8285154089284252 0.3869300325194652 0.3493374061379617 0.5080340446201296 0.14237726731943923 0.8487596503978638 4.167154550742378e-06 5.380160392201734 2.782385526554668 up KPS(ph)GLNGEASK ddPTM_PC-9_Lapatinib_30min_R1 2 KPSGLNGEASK 11 1 P16070;P16070-5;P16070-7;P16070-3;P16070-4;P16070-8;P16070-17;H0Y2P0;H0YD13;H0YE40;P16070-10;P16070-16;P16070-11;P16070-13;P16070-14;P16070-12;P16070-18;P16070-6;J3KN83 P16070 CD44 CD44 antigen 1 KPS(1)GLNGEASK;KPS(1)GLNGEASK 89.507 0.013581000000000001 54293900.0 149868.0 250392.0 77446.0 47633.2 89230.0 45832.7 41653.5 59793.0 94503.0 36376.9 True False 147730.85483757508 249812.23270803838 71078.68883020538 51136.30442769709 83981.66683292978 43872.542262242016 43810.11441785921 62571.20106507824 83859.07697929254 42664.598695827604 3.4626097362547665 5.8552579971288665 1.6659875166517515 1.1985652271633338 1.9684157217009706 1.0283125495923753 1.0268493260700382 1.4665836074346437 1.9655423827411638 1.0 15.38075185760708 -5.322647463486551 7.45053217312807 1.407765442280909 4.651025029764392 0.8063476593951033 0.6360846199281118 0.09114286126570391 9.870980458556923 0.15500888715011202 0.32633992367369746 4.7572123373699655e-06 5.322647463486551 3.2432595874834824 KPS(ph)ISITTESLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPSISITTESLK 12 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-3;Q9UKV3-2;G3V3B0;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 KPS(0.823)IS(0.17)IT(0.005)T(0.002)ES(0.001)LK 65.51100000000001 0.019004 5876400.0 27369.0 27156.0 34005.0 33243.0 35079.0 27117.0 35316.0 35986.0 31457.0 30219.0 True False 32002.03113760984 29851.868212248275 34815.80816468064 31380.502485260156 28205.5217667085 25694.936783249766 31970.61281430173 35041.40563031871 31916.9991142028 35697.46548652762 0.8964790833592248 0.8362461537644599 0.9753019630432945 0.8790680810967741 0.7901267325926372 0.7197972302248503 0.8955989557961078 0.9816216684499209 0.8940970648532014 1.0 15.123534026357856 -7.526774564442346 19.27998945022129 0.9504384998742154 0.8494665743821812 0.3396654973081281 0.0678485040398418 9.01258700230095 44575.353048408775 0.034231247119950875 0.020004219442865546 2.9732089781013574e-08 7.526774564442346 -0.10097192549203415 KPS(ph)LVASK ddPTM_PC-9_AZD4547_30min_R2 1 KPSLVASK 8 1 P56211;H3BQ52;H3BMD8;P56211-2 P56211;P56211-2 ARPP19 cAMP-regulated phosphoprotein 19 1 KPS(0.987)LVAS(0.013)K 57.567 0.037169 80710000.0 164920.0 185630.0 138830.0 122600.0 199310.0 124150.0 148480.0 336220.0 264210.0 155070.0 True False 217361.1294508993 245631.26730750047 136989.02349008954 94336.46415111814 171639.24684102728 116386.88087399835 161694.4323561261 284264.92456698493 278175.6012045946 149641.04649963463 1.4525501828232001 1.6414698577244995 0.9154508518518282 0.6304183668706733 1.1470064588291045 0.7777737699414079 1.0805486605342667 1.8996453928680526 1.8589525248025702 1.0 17.19114643481639 -7.745908963480493 24.81214276724931 1.659474151412078 1.0787603933409473 0.2740485851373111 0.36217055833086675 246.52151566940864 393856.0724838057 0.17919649731545648 0.10297894533291882 1.7951098771311118e-08 7.745908963480493 -0.5807137580711308 KPS(ph)PAASPATK ddPTM_PC-9_AZD4547_30min_R2 2 KPSPAASPATK 11 1 H0Y6J8;Q8N3F8 H0Y6J8;Q8N3F8 MICALL1 MICAL-like protein 1 1 KPS(0.999)PAAS(0.001)PATK;KPS(0.987)PAAS(0.01)PAT(0.002)K 91.712 0.011815 92521000.0 80076.0 116174.0 212143.0 243610.0 244900.0 238220.0 240140.0 275930.0 229890.0 253330.0 True False 105538.50231572996 153724.97359360877 209329.84520822647 187449.4782369813 210899.86228170982 223324.06574147363 261511.99478717824 233291.35874061033 242041.51607026343 244460.99380765052 0.43171919033746103 0.6288323188056919 0.8562913941720031 0.7667868616474346 0.8627137564844082 0.9135366025599647 1.0697493727483738 0.9543091317225487 0.9901028065880694 1.0 17.89924476157927 -4.595916067945454 0.5164268916259116 0.9991783216911918 9.941438054567932e-17 0.9022425230847585 0.05733473892945893 1.6059592736697204 0.2854508448365532 0.03651428592836695 1.0130206919287537 2.5356186185717948e-05 4.595916067945454 -0.9991783216911917 down KPS(ph)PAASPATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 KPSPAASPATK 11 1 H0Y6J8;Q8N3F8 H0Y6J8;Q8N3F8 MICALL1 MICAL-like protein 1 1 KPS(0.999)PAASPATK;KPS(0.999)PAAS(0.001)PATK;KPS(0.999)PAAS(0.001)PATK;KPS(0.998)PAAS(0.001)PAT(0.001)K 93.71600000000001 0.003186 144508000.0 165129.0 219698.0 287254.0 345681.0 389905.0 314927.0 328595.0 303638.0 270986.0 247604.0 True False 193082.0782535852 241508.16550650063 294103.2247768621 326313.6142829231 313505.91420646233 298411.6737227014 297468.10277821537 295667.82423105475 274948.6575948549 292492.64516781486 0.6601262679367756 0.825689703643446 1.0055063935304192 1.1156301523264074 1.0718420424779957 1.020236503900775 1.0170105392138866 1.0108555859974468 0.9400190471015287 1.0 18.158040822506102 -5.030333463531032 2.253712260045029 1.02936693265953 0.6479235224965574 0.8776023037607494 0.04394533298298401 0.13125439452390228 1.111314444065871 0.01315222768364222 0.08112367067339718 9.325379969028348e-06 5.030333463531032 -0.3814434101629727 KPS(ph)PAASPATK ddPTM_PC-9_Lapatinib_30min_R1 3 KPSPAASPATK 11 1 H0Y6J8;Q8N3F8 H0Y6J8;Q8N3F8 MICALL1 MICAL-like protein 1 1 KPS(0.974)PAAS(0.004)PAT(0.022)K;KPS(1)PAASPATK;KPS(1)PAASPATK 91.07600000000001 0.013338999999999998 94065000.0 247466.0 306384.0 296835.0 307493.0 271017.0 235782.0 224039.0 219273.0 260544.0 140885.0 True False 243937.08946029327 305674.5866721768 272430.372116235 330107.0609865781 255076.31289992313 225698.15349468694 235638.64318875395 229461.2240754416 231198.79107004835 165236.78453253754 1.4762880441567687 1.8499185126177822 1.6487271456349932 1.997781921988292 1.543701746687614 1.3659074408473717 1.4260665012054459 1.3886812474873433 1.3991968660254457 1.0 17.33417536552357 -6.566629055672266 3.8861935872499993 1.3492766126739164 1.7478866181890254 0.5773562888449142 0.17075707439677343 0.1638300325581347 5.263998824777248 0.05480681663630148 0.056251659282901066 2.712507479130183e-07 6.566629055672266 0.39861000551510894 KPS(ph)PAASPATKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPSPAASPATKK 12 2 H0Y6J8;Q8N3F8 H0Y6J8;Q8N3F8 MICALL1 MICAL-like protein 1 1 KPS(0.999)PAASPATKK 50.354 0.034468 10022000.0 42145.0 44775.0 82631.0 86879.0 115240.0 95462.0 75922.0 91892.0 95172.0 75109.0 True False 49279.31609830706 49219.96609233378 84601.2364198125 82011.45129551814 92659.54925726166 90455.80466875344 68730.11853232021 89479.93236762201 96563.71045226547 88725.66713748296 0.555412178777392 0.554743262916987 0.9535147962169781 0.9243261160092383 1.044337588509569 1.0194998537299198 0.7746362552092274 1.0085010939277614 1.0883402015184314 1.0 16.437063896649924 -5.268632471648112 5.563216952389218 0.9730483887713371 0.5508436101043512 0.8154878723436033 0.08023306052601199 0.06232980087122138 7.432962508321758 0.021812910550583788 0.05175985297751525 5.387254943569531e-06 5.268632471648112 -0.4222047786669859 KPS(ph)PEPEGEVGPPK ddPTM_PC-9_AZD4547_30min_R2 3 KPSPEPEGEVGPPK 14 1 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 KPS(1)PEPEGEVGPPK;KPS(1)PEPEGEVGPPK;KPS(1)PEPEGEVGPPK 93.75299999999999 0.0016640999999999997 177437700.0 242003.0 231987.0 284712.0 359190.0 344548.0 313694.0 284325.0 319152.0 344580.0 300219.0 True False 318954.9200248962 306972.2609969572 280936.5328524841 276384.2949301805 296713.4575313935 294078.6645903186 309629.3741894909 269834.39178336336 362793.79532598756 289708.4241895518 1.1009514856779203 1.0595903859395885 0.969721655966316 0.9540084852670575 1.024179598371839 1.0150849614159216 1.0687620667423365 0.9313998808913297 1.252272164128086 1.0 18.144242110580464 -8.247512237513698 24.981040195842144 1.1261361156599303 1.0154147610208817 0.25609254134129233 0.07545105181381234 898.2955495263545 1611275.09003577 0.048970992168625126 0.018287903835349596 5.6557182022903025e-09 8.247512237513698 -0.11072135463904864 KPS(ph)PEPEGEVGPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 KPSPEPEGEVGPPK 14 1 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 KPS(1)PEPEGEVGPPK;KPS(1)PEPEGEVGPPK;KPS(1)PEPEGEVGPPK;KPS(1)PEPEGEVGPPK;KPS(1)PEPEGEVGPPK;KPS(1)PEPEGEVGPPK 114.03 8.2245e-05 146775000.0 512354.0 519818.0 454653.0 591685.0 617238.0 523189.0 543880.0 532156.0 457378.0 401739.0 True False 599085.4127472297 571422.0956825188 465493.6518011035 558534.8077186531 496294.6447800564 495752.0478184039 492359.74904979067 518187.4688658886 464066.28797583457 474571.1005358256 1.2623723022131317 1.204081106155308 0.980872310335642 1.1769254535053364 1.0457751098195893 1.0446317680504849 1.0374836320498244 1.0919069203346283 0.9778646180769746 1.0 18.856264723339734 -1.5228787560628625 0.5550554333221954 1.036033965854671 12.160520649129317 0.6054993044176651 0.059264786980520165 92.17660757375012 0.830779152790052 0.02797045550478194 1224.8728788161563 0.029999999255169576 1.5228787560628625 11.124486683274647 KPS(ph)PEPEGEVGPPK ddPTM_PC-9_Lapatinib_30min_R1 4 KPSPEPEGEVGPPK 14 1 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 KPS(1)PEPEGEVGPPK;KPS(1)PEPEGEVGPPK;KPS(1)PEPEGEVGPPK;KPS(1)PEPEGEVGPPK 155.26 0.00010474 53118100.0 119544.0 178286.0 187288.0 195527.0 197038.0 199108.0 193607.0 195671.0 194701.0 169593.0 True False 117839.28063831503 177873.1897208596 171889.9035925868 209906.70783895094 185448.61223161267 190592.6149834177 203631.0231336733 204762.58899210475 172771.7230875764 198906.92408153214 0.592434281423067 0.8942533827929953 0.8641725489763693 1.055301160621789 0.932338645765781 0.9582000016514941 1.0237502996638004 1.0294392210709185 0.8686058762678222 1.0 17.6017339726508 -4.355357490857149 1.2348856461145108 0.9771486545115888 3.1942293342687997e-12 0.7787732468474076 0.06000295549177644 1.5977391819457263 1.0337737863232064 0.017113314373306595 2.571407592016847 4.412071168213582e-05 4.355357490857149 -0.9771486545083946 KPS(ph)PQAEEMLK ddPTM_PC-9_AZD4547_30min_R2 1 KPSPQAEEMLK 11 1 Q15013;Q15013-3 Q15013 MAD2L1BP MAD2L1-binding protein 1 KPS(1)PQAEEMLK 52.693000000000005 0.036611000000000005 5935000.0 24541.0 26244.0 27711.0 38415.0 44552.0 35880.0 31817.0 39495.0 26265.0 29158.0 True False 32344.52751548943 34726.85977060845 27343.53403395425 29559.015255833638 38366.723823498214 33636.41792798279 34648.651362303804 33391.95525481254 27653.31427893975 28137.187295004467 1.1495295239134276 1.2341979817141824 0.9717934400219483 1.0505319862259865 1.3635593146266585 1.1954435095207496 1.2314184427544184 1.1867552682048292 0.9828030779696795 1.0 14.7801904978054 -8.262382610436358 24.999999882476136 0.9914015142473718 1.1732211051031756 0.34437616334379173 0.10017266941444068 102.77749851511638 2723870.8835159424 0.08567297459114906 0.027043503871966915 5.465342578326547e-09 8.262382610436358 0.1818195908558038 KPS(ph)PQAEEMLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPSPQAEEMLK 11 1 Q15013;Q15013-3 Q15013 MAD2L1BP MAD2L1-binding protein 1 KPS(1)PQAEEMLK 48.177 0.045861 5939000.0 35256.0 32751.0 31953.0 35205.0 47084.0 37827.0 36059.0 36542.0 34467.0 30857.0 True False 41224.144462259224 36002.302836181465 32714.880702427334 33232.57798614997 37858.22819532207 35843.28552937231 32643.230475447555 35582.81121944941 34971.014669842276 36451.1298361224 1.1309428445042833 0.9876868837273691 0.8974997715985057 0.9117022746772884 1.0386023249629224 0.98332440422333 0.8955341198532264 0.976178554119535 0.9593945325444108 1.0 15.15367591244758 -4.785074182667878 3.8880657504842238 0.9560936046270891 1.1469122901299098 0.5831878078626485 0.04364248831285371 0.17038110014889657 4.6986025869020365 0.011367233361133985 0.09178064224297082 1.6403095648668448e-05 4.785074182667878 0.19081868550282066 KPS(ph)PQPS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 KPSPQPSSPR 10 1 G3V5E1;O75909-1;O75909;O75909-4 G3V5E1 CCNK Cyclin-K 2 KPS(0.998)PQPS(0.569)S(0.433)PR 69.456 0.033013 0.0 53184.0 44515.0 62843.0 42964.0 50711.0 50078.0 38623.0 47627.0 52713.0 37811.0 True False 52425.586407248906 44411.928252493424 57676.29112099518 46123.71588370251 47728.27868166199 47936.280677519644 40622.709956209575 49839.92429091168 46775.90684750166 44346.58097000943 1.182178766897568 1.0014735585259253 1.3005803347049532 1.040073775132629 1.0762561089870608 1.0809464817578123 0.9160280018809517 1.1238729841341606 1.0547804548705824 1.0 15.436535259549194 KPS(ph)PSESPEPWKPFPAVSPEPR ddPTM_PC-9_AZD4547_30min_R2 1 KPSPSESPEPWKPFPAVSPEPR 22 2 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 KPS(0.519)PS(0.135)ES(0.346)PEPWKPFPAVSPEPR 61.56100000000001 0.0019657 18258000.0 21047.0 19978.0 28887.0 32379.0 28876.0 29744.0 17610.0 25353.0 18161.0 28202.0 True False 27739.50819520419 26435.497808916945 28503.939505569495 24914.521800563234 24867.065836041813 27884.10297797992 19177.255884909635 21435.276403981814 19120.95338358366 27214.65656402073 1.0192856239044863 0.9713698847063947 1.0473745806240768 0.9154817640984527 0.9137379991382084 1.0245987456201904 0.7046664667546465 0.7876372187007653 0.7025976366302049 1.0 14.732096209604356 -7.2560854559841275 24.947263013637308 0.7810284301528841 0.9783413683359452 0.50811214666925 0.08759569943095184 318.7156818081241 1485099.6228197045 0.03240621526161675 0.024351560443488206 5.5451659017291674e-08 7.2560854559841275 0.19731293818306106 KPS(ph)PSESPEPWKPFPAVSPEPR ddPTM_PC-9_Lapatinib_30min_R1 1 KPSPSESPEPWKPFPAVSPEPR 22 2 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 KPS(0.451)PS(0.451)ES(0.097)PEPWKPFPAVSPEPR 70.11399999999999 0.00060257 14409000.0 19973.0 17404.0 19303.0 20050.0 18990.0 17589.0 14351.0 18445.0 14711.0 16616.0 True False 19688.181357400375 17363.702107298566 17715.98185173479 21524.543884839284 17873.045535776477 16836.759471961606 15094.024560017706 19302.022036783037 13054.09226630237 19488.0534605717 1.0102692604591614 0.8909921220417868 0.9090688245276947 1.1044994272202617 0.9171283100150195 0.8639528573762278 0.7745270501518271 0.9904540787429056 0.6698510086045 1.0 14.25030237558264 -6.606057746357909 4.260061416531173 0.8545375901345228 0.9719078375359347 0.21815892408748516 0.10496528127244047 0.33580773064007563 11.474256344180306 0.03398238523354396 0.03413137485189028 2.477092666871895e-07 6.606057746357909 0.11737024740141189 KPS(ph)VGVPPPAS(ph)PSYPR ddPTM_PC-9_AZD4547_30min_R2 1 KPSVGVPPPASPSYPR 16 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 2 KPS(1)VGVPPPAS(0.703)PS(0.295)Y(0.003)PR 74.308 0.028994 0.0 18671.0 16684.0 18662.0 33154.0 40449.0 30339.0 21711.0 34279.0 29789.0 24931.0 True False 24607.98961907434 22076.77672659775 18414.529686465805 25510.85752419389 34833.35455056294 28441.897533920535 23643.236940219955 28981.968203056553 31363.58572455116 24058.173278405793 1.0228536196121778 0.9176414381558008 0.7654167867763415 1.0603821507550617 1.4478802753419673 1.1822135124219717 0.9827527911872562 1.2046620442737552 1.3036561571656224 1.0 14.554239483317192 -5.997157046194782 24.331117719046574 1.1927902299240272 0.9050978958578164 0.4585622618780316 0.13872034950158763 56.7866743533147 485982.63163552736 0.0400064939794032 0.05893994819428018 1.0065676158755485e-06 5.997157046194782 -0.28769233406621075 KPS(ph)VGVPPPASPSYPR ddPTM_PC-9_AZD4547_30min_R2 2 KPSVGVPPPASPSYPR 16 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 KPS(1)VGVPPPASPSYPR;KPS(1)VGVPPPASPSYPR 74.793 0.018904 49342200.0 112594.0 104925.0 128397.0 168230.0 218850.0 158756.0 102179.0 228307.0 151925.0 152530.0 True False 148396.5498993122 138839.95432979317 126694.37188689067 129447.17262759064 188466.4551259782 148828.96222337862 111272.73305304829 193027.39912293915 159955.44533896513 147189.97112651903 1.0081974251612296 0.943270477378187 0.8607541051692231 0.8794564713673506 1.280430002693454 1.0111352090384662 0.7559803986740535 1.3114167877444582 1.086727880403437 1.0 17.16731985032264 KPS(ph)VGVPPPASPSYPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KPSVGVPPPASPSYPR 16 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 KPS(1)VGVPPPASPSYPR;KPS(1)VGVPPPASPSYPR 99.796 0.00085458 51784000.0 344800.0 303510.0 276430.0 238510.0 332500.0 186275.0 141974.0 203673.0 122134.0 124514.0 True False 403167.8298895788 333640.46697228926 283021.13956661324 225147.05795985291 267349.0118712209 176506.4110816038 128525.1949172521 198326.7995593818 123919.97869517282 147087.40254771864 2.741008562978611 2.2683143572682805 1.9241698110400345 1.5307025214943875 1.8176200493069863 1.2000103885466393 0.8738015131891086 1.3483602002900275 0.8424921274612232 1.0 17.166314165215894 -3.890605164761338 0.3376346750228748 0.9021702399475268 5.64655828391278 0.8973117998128769 0.1914596862624054 3.640407512122753 0.20899463756191983 0.1824492601410688 7.913936558224798 0.00012864556990178482 3.890605164761338 4.7443880439652535 up KPS(ph)VGVPPPASPSYPR ddPTM_PC-9_Lapatinib_30min_R1 2 KPSVGVPPPASPSYPR 16 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 KPS(1)VGVPPPASPSYPR;KPS(1)VGVPPPASPSYPR 117.13 0.00021698 8778100.0 48143.0 39920.0 36372.0 44394.0 27058.0 24892.0 20983.1 23357.0 33660.0 40581.0 True False 47456.471991655075 39827.56769267751 33381.634559980215 47658.88285404268 25466.50163807478 23827.427186086108 22069.502246903172 24442.251488920636 29868.85634448628 47595.371779216424 0.9970816534808117 0.8367949698434566 0.701363038297708 1.0013343960232282 0.5350625635662183 0.5006248779107317 0.46369009048355225 0.5135426108719648 0.6275580004509846 1.0 15.538533670817825 -6.273468684240033 24.882797867489124 0.5699645863465196 0.8677057279638689 0.39217637507790004 0.164915570612743 650.029428442869 1344592.882471785 0.048772841926912995 0.05572159784550471 5.32759638744896e-07 6.273468684240033 0.2977411416173493 KPS(ph)VPDSASPADDSFVDPGER ddPTM_PC-9_AZD4547_30min_R2 2 KPSVPDSASPADDSFVDPGER 21 1 P16333-2;P16333;C9K098;C9JVV5;H7C5C7;C9J869;C9JAB9 P16333-2 NCK1 Cytoplasmic protein NCK1 1 KPS(0.997)VPDS(0.003)ASPADDSFVDPGER;KPS(0.996)VPDS(0.004)ASPADDSFVDPGER 79.408 0.00045364 15887900.0 51788.0 54474.0 58421.0 76605.0 79763.0 56624.0 56183.0 76305.0 69478.0 70681.0 True False 68255.50674268232 72081.65520287018 57646.29936839669 58944.90078545184 68689.28425959978 53083.29232870951 61183.17815910725 64513.815564463155 73150.46523785175 68206.47970362197 1.00071880324675 1.0568153570758532 0.8451733562395759 0.8642126238091378 1.007078573151345 0.7782734508418065 0.897028822260977 0.9458605083387301 1.0724855696366813 1.0 16.057621183200958 -8.119347608469479 4.93436162556091 1.034367827458392 0.9193465622096404 0.23919693873777237 0.0805579455134108 0.33739644633031307 11.897550216612768 0.06024052030705489 0.02167955790699187 7.597179567295705e-09 8.119347608469479 -0.11502126524875167 KPS(ph)VPDSASPADDSFVDPGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KPSVPDSASPADDSFVDPGER 21 1 P16333-2;P16333;C9K098;C9JVV5;H7C5C7;C9J869;C9JAB9 P16333-2 NCK1 Cytoplasmic protein NCK1 1 KPS(0.995)VPDS(0.005)ASPADDSFVDPGER;KPS(0.991)VPDS(0.007)AS(0.002)PADDSFVDPGER 67.285 0.0017182000000000002 4216000.0 20353.9 21681.0 19547.0 22900.0 25818.0 17975.8 19624.8 23965.0 19901.7 15287.0 True False 23799.413262150487 23833.346395262724 20013.074612410324 21616.987242801715 20759.14823606375 17033.117403412663 17765.796872751973 23335.944143016404 20192.724712182662 18058.412088174573 1.317912845600382 1.3197919218417786 1.1082411075066643 1.1970591399316584 1.1495555719241635 0.9432234307337954 0.9837961824110649 1.2922478471015615 1.1181893852896252 1.0 14.140383418922294 -5.220566313917938 1.0593027947427194 1.0892845670109248 1.382105647578782 0.43266151143994114 0.09953307831691581 1.0340275225059754 1.5249170455495573 0.03627318003444855 0.28968822796965715 6.017743688861178e-06 5.220566313917938 0.2928210805678573 KPS(ph)VPDSASPADDSFVDPGER ddPTM_PC-9_Lapatinib_30min_R1 2 KPSVPDSASPADDSFVDPGER 21 1 P16333-2;P16333;C9K098;C9JVV5;H7C5C7;C9J869;C9JAB9 P16333-2 NCK1 Cytoplasmic protein NCK1 1 KPS(0.856)VPDS(0.138)AS(0.006)PADDSFVDPGER;KPS(0.941)VPDS(0.052)AS(0.007)PADDSFVDPGER 53.625 0.010298 14198200.0 51232.0 54306.0 61218.0 54024.0 63776.0 65721.0 63034.0 58041.0 72788.0 70106.0 True False 50501.42228520184 54180.2577935507 56184.892348313726 57997.10517878093 60024.82106844025 62910.266033133754 66297.59209226917 60737.79674908777 64589.84894837989 82223.72868962667 0.6141952340282653 0.6589370082943717 0.6833172521328627 0.7053572746342484 0.730018232267457 0.7651108388747943 0.8063072929047702 0.7386893992409084 0.7855378243936112 1.0 16.327267176409457 -14.522878744940444 0.06790419596841775 1.9811001591612953 0.3598325912444101 0.9330717359879458 0.025979989096615568 83.1168998949496 0.4061290677992289 12.86653908948213 1.6946470149066246 3.000000002347902e-15 14.522878744940444 -1.6212675679168853 KPS(ph)VSEEVQATPNK ddPTM_PC-9_AZD4547_30min_R2 3 KPSVSEEVQATPNK 14 1 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 KPS(0.592)VS(0.098)EEVQAT(0.31)PNK;KPS(0.98)VS(0.02)EEVQATPNK;KPS(0.959)VS(0.028)EEVQAT(0.012)PNK 142.19 9.2509e-06 57931300.0 88448.0 80774.0 103654.0 132240.0 117746.0 114268.0 96230.0 116803.0 87730.0 100815.0 True False 116572.62416731213 106882.615878339 102279.4802336796 101754.11108763352 101399.00034390434 107122.80389617445 104794.28357778872 98753.78021592252 92367.22869565521 97285.49753569772 1.1982528446702678 1.0986490133241056 1.0513332698550408 1.0459329875996788 1.0422827956109 1.101117911812776 1.0771829947144562 1.015092513451823 0.9494449947358514 1.0 16.56993713632631 -1.5228787452803862 0.6757338068506054 1.0320330933889525 18.34380388648915 0.6388797570001434 0.0384675036189261 182.488527934364 1.0665172307166302 0.017000083227907792 4751.791666192087 0.029999999999996637 1.5228787452803862 17.311770793100198 KPS(ph)VSEEVQATPNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KPSVSEEVQATPNK 14 1 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 KPS(0.442)VS(0.386)EEVQAT(0.172)PNK;KPS(0.946)VS(0.052)EEVQAT(0.002)PNK;KPS(0.999)VS(0.001)EEVQATPNK 157.74 0.00058468 43173300.0 87717.0 98134.0 92085.0 109726.0 129274.0 121810.0 148992.0 136708.0 131357.0 124931.0 True False 102565.75561027873 107876.09497498818 94280.65563430722 103578.40795649184 103943.68770117383 115422.06916575032 134878.39915133233 133119.55985409935 133277.8476219711 147580.00134674794 0.6949841081061818 0.7309668924688983 0.6388443879519233 0.7018458260691314 0.7043209564482384 0.7820983067655579 0.913934123326287 0.9020162531461635 0.9030888088205591 1.0 17.171137708622005 -7.098469553063294 1.7678495011322568 0.9310238363696575 0.6901539389427374 0.919090561236054 0.033026598989518596 0.09509251178922927 0.589409526095737 0.015965600983523193 0.011262310127188037 7.971323729217166e-08 7.098469553063294 -0.2408698974269201 KPS(ph)VSEEVQATPNK ddPTM_PC-9_Lapatinib_30min_R1 4 KPSVSEEVQATPNK 14 1 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 KPS(0.993)VS(0.004)EEVQAT(0.003)PNK;KPS(0.909)VS(0.091)EEVQATPNK;KPS(0.959)VS(0.008)EEVQAT(0.033)PNK;KPS(0.915)VS(0.085)EEVQATPNK 190.24 8.0454e-37 88673800.0 148609.0 132366.0 155454.0 118621.0 190743.0 210792.0 194368.0 200977.0 215072.0 178614.0 True False 146489.80840844713 132059.51465954294 142673.17218979326 127344.78404805585 179523.87175516677 201776.91754015195 204431.42399007184 210315.1251226098 190848.32655143653 209487.19191180536 0.6992781137193328 0.6303942186362417 0.6810591658981187 0.6078881619725388 0.8569682476375299 0.9631945308861677 0.9758659807523602 1.00395219012317 0.9110262293829599 1.0 17.67650251439872 -6.46010968959883 3.0252936599218114 0.9704181303148414 0.6547905246870303 0.9469123871813275 0.03523272707558494 0.052554308213274344 0.9478668901845472 0.01153199356780884 0.01277609381824182 3.466492863112167e-07 6.46010968959883 -0.3156276056278111 KPSAPS(ph)PPDQTPEEDLVIVK ddPTM_PC-9_AZD4547_30min_R2 2 KPSAPSPPDQTPEEDLVIVK 20 1 Q15776;Q15776-2 Q15776 ZKSCAN8 Zinc finger protein with KRAB and SCAN domains 8 1 KPS(0.013)APS(0.519)PPDQT(0.468)PEEDLVIVK;KPS(0.285)APS(0.715)PPDQTPEEDLVIVK 90.45299999999999 0.00030825 8495000.0 65772.0 72867.0 77952.0 95083.0 76435.0 88271.0 75284.0 99779.0 67026.0 82945.0 True False 86686.12785741317 96419.83275815149 76918.30554706803 73163.08336770597 65823.31961413818 82751.40041585741 81984.13015556731 84360.44824332028 70568.85752370903 80041.12079649324 1.0830199151985271 1.204628718322193 0.9609848635507608 0.9140687016830403 0.8223687894313197 1.033861090304509 1.0242751393251255 1.0539638551265298 0.8816575382937515 1.0 16.288453748644947 -5.273712337877577 24.315047273824838 0.9615027564091503 1.143824311594275 0.49379524444125455 0.07388188278031427 392.9933989997019 778595.4426947478 0.020350436002144614 0.04288240242748607 5.324608267115841e-06 5.273712337877577 0.18232155518512472 KPSAPS(ph)PPDQTPEEDLVIVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KPSAPSPPDQTPEEDLVIVK 20 1 Q15776;Q15776-2 Q15776 ZKSCAN8 Zinc finger protein with KRAB and SCAN domains 8 1 KPS(0.002)APS(0.986)PPDQT(0.013)PEEDLVIVK;KPS(0.029)APS(0.97)PPDQT(0.001)PEEDLVIVK 102.84 9.5802e-05 9088600.0 94008.0 105130.0 96290.0 107124.0 120012.0 107993.0 122762.0 80703.0 89956.0 90370.0 True False 109921.69765736513 115566.6116200345 98585.91878185849 101122.18958069399 96496.51011335052 102329.65696918861 111133.09464008706 78584.63176189648 91271.43631996775 106753.36563147356 1.0296789895770506 1.0825570785185865 0.9234923713992292 0.9472505993842001 0.9039200735503644 0.9585614126906672 1.0410266129101062 0.7361325921393506 0.8549747896010002 1.0 16.703922029090954 -4.9177301577987595 0.5731754002783489 0.8969673631672462 1.1583069110164266 0.25607703240219426 0.08287802344276513 4.626752933980872 1.2899248913927999 0.04767226387354311 0.7890006877057584 1.208564524859789e-05 4.9177301577987595 0.26133954784918034 KPSAPS(ph)PPDQTPEEDLVIVK ddPTM_PC-9_Lapatinib_30min_R1 1 KPSAPSPPDQTPEEDLVIVK 20 1 Q15776;Q15776-2 Q15776 ZKSCAN8 Zinc finger protein with KRAB and SCAN domains 8 1 KPS(0.234)APS(0.766)PPDQTPEEDLVIVK 75.764 0.0010419000000000001 4442000.0 24710.0 22721.0 28215.0 20687.0 14609.0 23521.0 27614.0 24661.0 22015.0 18660.0 True False 24357.630868740966 22668.390920474085 25895.271613049626 22208.390989808995 13749.727342399088 22515.061660129013 29043.717803660285 25806.84008940668 19535.438871772596 21885.356137112907 1.1129647932681161 1.0357789372242985 1.183223679377863 1.014760319670937 0.6282615305072635 1.0287729164227883 1.3270845409916963 1.1791830083881418 0.8926260440717548 1.0 14.417678240477114 -9.95863753725729 15.557745949897404 1.0000174375378725 1.047206830657399 0.0054370484540593456 0.1787477282188103 0.0 0.0 0.18616302327251794 0.04515116520805355 1.0999234540116518e-10 9.95863753725729 0.04718939311952641 KPSDS(ph)LSVASSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPSDSLSVASSSR 13 1 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 KPS(0.069)DS(0.692)LS(0.035)VAS(0.161)S(0.035)S(0.008)R 70.72800000000001 0.043414 0.0 11209.0 9991.5 9378.1 16114.0 15021.0 11176.0 11941.0 11214.0 11672.0 10436.0 True False 13106.46231215859 10983.390088476905 9601.70947064231 15211.184822292866 12077.742879150728 10589.910885776428 10809.862034646536 10919.644382215145 11842.680918745438 12327.964188669452 1.063148960491356 0.8909329975643232 0.7788560482246677 1.2338764608250048 0.9797029496769061 0.859015383538309 0.8768570275846361 0.8857621757411752 0.9606355710888556 1.0 13.58964695565625 -6.67210044853171 8.824486716407591 0.9069624083906834 0.9861659141906262 0.08682267077482486 0.1159925841639083 0.7370024687974946 65.40225949807113 0.039612417767486585 0.0395714714061577 2.1276468828725039e-07 6.67210044853171 0.07920350579994273 KPSDSLSVAS(ph)SSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPSDSLSVASSSR 13 1 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 KPS(0.002)DS(0.003)LS(0.038)VAS(0.447)S(0.062)S(0.447)R 61.523999999999994 0.024338 9419900.0 40629.0 35365.0 30262.0 40863.0 47764.0 38892.0 46347.0 53299.0 26096.0 35826.0 True False 47506.68724067193 38875.803480857285 30983.560849274094 38573.57858963347 38404.98707674294 36852.43505454696 41956.67663677771 51899.95772495854 26477.604631218364 42320.97020154005 1.1225330377455092 0.9185943350477018 0.7321089450862025 0.9114530788386744 0.9074694387640809 0.8707842679184588 0.9913921263376642 1.2263413971324768 0.6256379403668504 1.0 15.369085080935848 -7.271406539531078 23.360959451508307 0.9797046573726055 0.9026570509628389 0.015911830305028962 0.16295518724124752 1064.253055888483 2494368.3371675117 0.06609835278926413 0.045249613700602064 5.352953372989936e-08 7.271406539531078 -0.0770476064097666 KPSGDSQPSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 KPSGDSQPSSPR 12 1 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 KPSGDS(0.023)QPS(0.134)S(0.843)PR 87.863 0.0038266999999999997 5065500.0 18535.0 17535.0 20344.0 29939.0 28430.0 21030.0 19162.0 26586.0 23710.0 27160.0 True False 24428.74444805008 23202.84583438575 20074.22526746655 23037.026102939028 24482.98523752144 19714.990775514976 20867.380878287247 22477.744585503122 24963.26219507565 26209.136666860606 0.9320697876682947 0.8852960755370445 0.7659247049083013 0.8789692844811458 0.9341393251033046 0.7522182445804494 0.7961872664303518 0.8576301032427545 0.9524641163262633 1.0 14.67778221139386 -8.363172185591376 2.9880039942364265 0.9970066750270358 0.8466801972767807 0.42607112875953435 0.05964496510889147 0.24650153400365737 4.057785067206628 0.059227844320035763 0.01611746820329784 4.3333903754027854e-09 8.363172185591376 -0.1503264777502551 KPSGDSQPSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 KPSGDSQPSSPR 12 1 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 KPSGDSQPS(0.032)S(0.968)PR 141.34 3.4123000000000005e-05 0.0 2867.6 3474.0 3281.1 896.36 4920.9 5695.5 6182.9 5281.7 6424.9 6352.9 True False 2826.707498146565 3465.9561664419216 3011.3406234122676 962.2813045693039 4631.462336861636 5451.916741858965 6503.020308837951 5527.107063793817 5701.260104803622 7450.990300292854 0.3793733965853457 0.46516718271740276 0.40415307255116273 0.12914810861201662 0.6215901712661739 0.7317036423527061 0.8727726176992012 0.7417949616142406 0.7651681018266175 1.0 12.863216469481715 -6.55614373452144 3.1996966609098783 0.8095444893843611 0.3567492325781329 0.8005592940523886 0.11167263465257286 0.11267675422888239 2.3850263450515374 0.03840860130005262 0.03997496268982327 2.7787934433912097e-07 6.55614373452144 -0.4527952568062282 KPSGLNGEAS(ph)KSQEMVHLVNK ddPTM_PC-9_Lapatinib_30min_R1 1 KPSGLNGEASKSQEMVHLVNK 21 2 P16070;P16070-5;P16070-7;P16070-3;P16070-4;P16070-8;P16070-17;H0Y2P0;H0YD13;H0YE40;P16070-10;P16070-16;P16070-11;P16070-13;P16070-14;P16070-12;P16070-18;P16070-6 P16070 CD44 CD44 antigen 1 KPS(0.047)GLNGEAS(0.581)KS(0.372)QEMVHLVNK 44.577 0.025261000000000002 33137000.0 78716.0 71199.0 29170.0 25334.0 37633.0 18872.0 17078.0 14003.0 44117.0 11335.0 True False 77593.49540525368 71034.14308995352 26771.75519945625 27197.14687174657 35419.5009293247 18064.888552780685 17962.215276704224 14653.630500464782 39148.07888739457 13294.239647061884 5.836625295257285 5.343227215379146 2.013786114151552 2.0457843091280004 2.664274292449109 1.3588508280556795 1.35112768789857 1.1022541258087921 2.9447399721011167 1.0 13.698513645366141 -5.247796372975593 3.8320055295793796 1.7951831133057499 5.745656457756296 0.86286667810487 0.6047222726872545 0.07125328506466604 2.383934319444147 0.1607548094899107 0.43835120796039345 5.65201918099984e-06 5.247796372975593 3.9504733444505464 KPSGLNGEASKS(ph)QEMVHLVNK ddPTM_PC-9_Lapatinib_30min_R1 1 KPSGLNGEASKSQEMVHLVNK 21 2 P16070;P16070-5;P16070-7;P16070-3;P16070-4;P16070-8;P16070-17;H0Y2P0;H0YD13;H0YE40;P16070-10;P16070-16;P16070-11;P16070-13;P16070-14;P16070-12;P16070-18;P16070-6 P16070 CD44 CD44 antigen 1 KPS(0.002)GLNGEAS(0.012)KS(0.986)QEMVHLVNK 42.716 0.022658 28503000.0 162800.0 170570.0 74683.0 59815.0 99271.0 59362.0 62020.0 63570.0 118150.0 45973.0 True False 160478.44214613634 170175.0556447895 68542.85202471688 64213.99463699061 93432.07495429525 56823.225639580676 65231.09213380939 66523.69427369461 104842.70282534325 53919.37179482806 2.976266911209255 3.1561023428153643 1.271210137342355 1.190926238557364 1.732810896050856 1.0538554836247398 1.209789542467673 1.2337624133832277 1.944434798392806 1.0 15.718516067579499 -5.261998029083622 24.99769659093743 1.333268290169957 3.0661847700691207 0.8596545756891797 0.28066519252626504 14.9569641679315 669313.104563169 0.07074111115000697 0.16320879895922877 5.470184453689088e-06 5.261998029083622 1.7329164798991636 KPSGS(ph)PDLWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPSGSPDLWK 10 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 KPS(0.109)GS(0.891)PDLWK 96.866 0.0078826 6776600.0 36897.0 41916.0 36140.0 42760.0 39679.0 32018.0 42284.0 32288.0 26881.0 24431.0 True False 43142.9333510318 46077.14346680653 37001.71466171322 40364.295829790455 31904.184788084807 30338.919715532356 38278.553410350396 31440.474211963854 27274.0837711443 28860.146904310404 1.494896526136123 1.5965664907937347 1.282104168921844 1.3986171298304046 1.105475481253346 1.051239268328225 1.3263464506008216 1.089407975510619 0.9450431372222426 1.0 14.816791023023075 -4.969556149603889 0.34507857942747544 0.998433155595352 1.9678402578530405 0.727074125080908 0.11036464866938309 3.1650186308171913 0.3343599150438898 0.11236784549584494 1.2738870875350132 1.0726149612962681e-05 4.969556149603889 0.9694071022576886 KPSLVSDLPWEGAAPQS(ph)PSFSGSEDSGSPK ddPTM_PC-9_AZD4547_30min_R2 3 KPSLVSDLPWEGAAPQSPSFSGSEDSGSPK 30 1 Q13425;Q13425-2;H7BY41;H0YCS0 Q13425 SNTB2 Beta-2-syntrophin 1 KPSLVSDLPWEGAAPQS(0.998)PS(0.001)FSGSEDSGSPK;KPSLVSDLPWEGAAPQS(0.963)PS(0.035)FS(0.002)GSEDSGSPK;KPSLVSDLPWEGAAPQS(0.997)PS(0.002)FSGSEDSGSPK 181.02 1.7894e-23 40390700.0 92749.0 94751.0 113278.0 133630.0 118576.0 119107.0 103537.0 123081.0 107921.0 112098.0 True False 122241.25270095462 125377.40779320685 111775.85970546964 102823.66806291927 102113.7691707473 111659.22046121063 112751.59242225406 104061.65957001092 113625.48373491186 108173.48313997558 1.1300482258001756 1.1590401284478336 1.0333018449709401 0.9505441174512824 0.9439815212256125 1.0322235840064846 1.0423219179912553 0.961988618184329 1.0504005273444088 1.0 16.72298736518249 -5.366366410439829 4.058029234634482 0.9966352183234164 1.14458202401893 0.7193784406271759 0.0361160164051286 0.11501858480250354 3.267608776321539 0.010015871985848931 0.022629495209344996 4.301635321564354e-06 5.366366410439829 0.14794680569551355 KPSLVSDLPWEGAAPQS(ph)PSFSGSEDSGSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KPSLVSDLPWEGAAPQSPSFSGSEDSGSPK 30 1 Q13425;Q13425-2;H7BY41;H0YCS0 Q13425 SNTB2 Beta-2-syntrophin 1 KPSLVSDLPWEGAAPQS(0.997)PS(0.002)FSGSEDSGSPK;KPSLVSDLPWEGAAPQS(0.998)PS(0.002)FSGSEDSGSPK 126.28 1.5099000000000003e-17 16059600.0 39391.0 46996.0 45945.0 68233.0 89485.0 88282.0 111599.0 86649.0 94657.0 73013.0 True False 46059.118292286475 51661.45229425616 47040.50304738279 64410.12622437064 71951.05662344738 83652.33650842114 101027.5348132082 84374.55556220432 96041.17955154952 86249.67892940981 0.5340207507321053 0.5989755896545187 0.5453991670610463 0.7467868521236637 0.8342182546828377 0.9698857728721003 1.171338097338231 0.9782593582900155 1.1135250674979724 1.0 16.39623146580228 -6.3535959302770815 1.1755732760823192 1.0683936607908666 0.5513897695129868 0.922202807318952 0.06190302427040096 0.11363078467983102 0.32571976906925304 0.025749906925967386 0.034513622677755665 4.430003503855094e-07 6.3535959302770815 -0.5170038912778798 KPSLVSDLPWEGAAPQS(ph)PSFSGSEDSGSPK ddPTM_PC-9_Lapatinib_30min_R1 2 KPSLVSDLPWEGAAPQSPSFSGSEDSGSPK 30 1 Q13425;Q13425-2;H7BY41;H0YCS0 Q13425 SNTB2 Beta-2-syntrophin 1 KPSLVSDLPWEGAAPQS(0.998)PS(0.001)FSGSEDSGSPK;KPSLVSDLPWEGAAPQS(0.615)PS(0.366)FS(0.018)GS(0.001)EDSGSPK 147.23 1.1712e-15 12385800.0 76172.0 90125.0 68796.0 67887.0 79585.0 87364.0 87506.0 92075.0 98210.0 75648.0 True False 75085.77331176608 89916.32109976347 63139.85844023965 72879.63644439328 74903.96677013017 83627.64537543082 92036.63250985357 96353.1406363132 87148.55560285192 88723.65600537612 0.8462880892466417 1.0134424701154683 0.7116462653028383 0.8214228282024043 0.8442389565821254 0.9425631127099122 1.037340396616171 1.0859915492039098 0.9822471201769598 1.0 16.437031194915527 -6.9954319406434085 2.7604487339086035 1.0330944682308145 0.8474633342242295 0.5702824787483773 0.07311819417359443 0.20660068670415987 3.1868489109671048 0.030540673980027862 0.024624883364224227 1.0105738576347907e-07 6.9954319406434085 -0.18563113400658504 KPSLVSDLPWEGAAPQSPSFSGSEDSGS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KPSLVSDLPWEGAAPQSPSFSGSEDSGSPK 30 1 Q13425;Q13425-2;H7BY41;H0YCS0 Q13425 SNTB2 Beta-2-syntrophin 1 KPSLVSDLPWEGAAPQS(0.004)PS(0.016)FS(0.043)GS(0.167)EDS(0.285)GS(0.485)PK;KPSLVSDLPWEGAAPQSPSFS(0.004)GS(0.079)EDS(0.149)GS(0.767)PK 121.09 1.3627999999999999e-17 13035800.0 151412.0 183548.0 118887.0 149990.0 163541.0 100465.0 137465.0 118384.0 102076.0 112897.0 True False 177043.06107668427 201769.43241352704 121721.71696145818 141586.54657414107 131496.31503889136 95196.43854147536 124443.32003958504 115276.5454382162 103568.66839118033 133364.33240783974 1.3275143202102282 1.5129189999354442 0.9127006806379278 1.0616522725218396 0.9859931262338133 0.7138073338106351 0.9331079591732708 0.8643731300336771 0.7765844624367655 1.0 17.025013351313653 -5.268388844281856 24.935793614606194 0.9036996501445357 1.420216670776769 0.7893305306829378 0.10625077529494376 199.52527751636205 715930.7610162605 0.028634049591183045 0.06172627536485774 5.390277894563208e-06 5.268388844281856 0.5165170206322333 KPSLVSDLPWEGAAPQSPSFSGSEDSGS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 KPSLVSDLPWEGAAPQSPSFSGSEDSGSPK 30 1 Q13425;Q13425-2;H7BY41;H0YCS0 Q13425 SNTB2 Beta-2-syntrophin 1 KPSLVSDLPWEGAAPQSPS(0.002)FS(0.005)GS(0.136)EDS(0.072)GS(0.785)PK 121.36 1.2713e-17 5556900.0 43820.0 62748.0 38522.0 48674.0 50524.0 40784.0 41962.0 43786.0 39166.0 34384.0 True False 43195.1187643962 62602.71086122563 35354.86985922022 52253.64833170413 47552.27765400586 39039.76339214748 44134.5870383571 45820.45740865177 34754.712643735875 40327.22858619992 1.0711154790135435 1.552368289514654 0.876699716263635 1.2957411199237594 1.1791605652335448 0.9680745432009921 1.0944116068878602 1.1362163732801527 0.8618175327731057 1.0 15.299466642165777 -6.499813505238666 0.4473118105939097 0.9714674694490606 1.2806871759951712 0.19680777694737717 0.1759099771254166 2.223604670270702 0.8821870967042622 0.1584930417892421 0.3012324924297274 3.163635897228875e-07 6.499813505238666 0.30921970654611064 KPSPAAS(ph)PATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPSPAASPATK 11 1 H0Y6J8;Q8N3F8 H0Y6J8;Q8N3F8 MICALL1 MICAL-like protein 1 1 KPS(0.113)PAAS(0.56)PAT(0.328)K 92.8 0.003415 13935000.0 99412.0 146900.0 179880.0 190640.0 223350.0 209020.0 208380.0 196040.0 189140.0 163320.0 True False 116240.48812349998 161483.26117172153 184169.02139869853 179959.0588632188 179586.1708313903 198058.62324131973 188640.73785944597 190894.15772154945 191905.8146822748 192928.62315959163 0.6025051452699437 0.837010385121246 0.9545966709478505 0.9327753234125122 0.9308425462759646 1.026590145089485 0.9777747581985349 0.9894548283985872 0.9946985135716707 1.0 17.557707673951313 -4.327348829921398 1.0487229893341676 0.9834150779757242 1.2853933142925625e-16 0.9526030294862194 0.02580164715440314 0.8230262599199155 0.3855185034173149 0.008551536508366717 1.1367027832209395 4.705991843110543e-05 4.327348829921398 -0.9834150779757241 KPSPAASPAT(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 KPSPAASPATK 11 1 H0Y6J8;Q8N3F8 H0Y6J8;Q8N3F8 MICALL1 MICAL-like protein 1 1 KPS(0.002)PAAS(0.298)PAT(0.7)K 74.789 0.019056 35158000.0 48964.0 55906.0 92473.0 114180.0 121300.0 126530.0 106020.0 120120.0 102880.0 107680.0 True False 64533.533485531334 73976.52119858394 91246.74759921507 87857.56506341495 104459.58879040972 118618.05909776095 115455.57461204534 101558.2140829998 108318.02676631736 103910.15597524108 0.6210512618314988 0.7119277274130019 0.8781311772927821 0.8455147068044916 1.0052875756947142 1.1415444234923904 1.1111096266620484 0.977365620615547 1.042420019003018 1.0 16.664977141759444 -5.49834645405632 0.883783133054632 1.05790163266007 0.5822572377359768 0.8636884590526329 0.059039932596446416 0.3558124384320998 0.42729376402457386 0.026007725429672238 0.13380302684699177 3.1743407618969615e-06 5.49834645405632 -0.4756443949240933 KPSPAASPAT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 2 KPSPAASPATK 11 1 H0Y6J8;Q8N3F8 H0Y6J8;Q8N3F8 MICALL1 MICAL-like protein 1 1 KPSPAAS(0.001)PAT(0.999)K;KPSPAAS(0.013)PAT(0.987)K 121.18 0.00067322 50841000.0 249920.0 180138.0 215630.0 188612.0 224086.0 195783.0 192546.0 198214.0 212750.0 159801.0 True False 246356.09497028563 179720.9015286461 197901.73375587026 202483.15567118782 210905.70205002694 187409.81748246404 202515.08974518656 207423.74605578277 188787.85464318062 187422.38992855186 1.3144432480249566 0.9589083865442027 1.0559129772665543 1.0803573455037967 1.1252961939628838 0.9999329191880831 1.0805277310911907 1.1067180721303134 1.0072854940925111 1.0 17.515933785541613 -4.748364866763503 24.999821174247884 1.0529238353315395 1.3144438741618116 0.7108851443361455 0.051172104930616635 356.5116411894677 681647.1043899456 0.012517997805557277 0.23083212751291296 1.7849873112518006e-05 4.748364866763503 0.2615200388302721 KPSPQPS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 2 KPSPQPSSPR 10 1 G3V5E1;O75909-1;O75909;O75909-4 G3V5E1 CCNK Cyclin-K 1 KPSPQPS(0.5)S(0.5)PR;KPSPQPS(0.5)S(0.5)PR 80.17 0.0082619 48032200.0 56503.0 72349.0 89320.0 99331.0 83710.0 78026.0 61050.0 91745.0 61909.0 64537.0 True False 74469.77866458984 95734.39938819353 88135.5584393488 76431.77259865188 72088.31143977899 73147.02188541746 66483.33173047897 77567.91834036639 65181.38335027157 62277.57927353401 1.195771889872366 1.5372209470074507 1.4152052707803884 1.2272759071599457 1.1575323299442088 1.1745321950319065 1.0675323688878875 1.2455191618748465 1.0466267974865167 1.0 15.926425247570428 -5.9603973453022885 2.6594314070852603 1.1281951681043247 1.3986407713546734 0.5723455753777065 0.1025552557613843 0.19112203135432784 2.7410700111365505 0.029908080108810953 0.046345690823058304 1.095475463590659e-06 5.9603973453022885 0.2704456032503486 KPSPQPS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPSPQPSSPR 10 1 G3V5E1;O75909-1;O75909;O75909-4 G3V5E1 CCNK Cyclin-K 1 KPS(0.163)PQPS(0.418)S(0.418)PR 54.871 0.042372 29591000.0 33963.0 26046.0 32493.0 36285.0 36992.0 28940.0 38877.0 35780.0 26397.0 29957.0 True False 39712.26510017331 28631.674747982717 33267.75635038871 34252.069087557225 29743.683149293895 27422.335454041662 35194.28911489433 34840.812912043664 26783.006186782317 35387.96696051846 1.1221968513896086 0.8090793907411075 0.9400866793931614 0.9679015786855308 0.8405027387551887 0.7749056475789109 0.9945270140598862 0.9845384153013016 0.7568393577586274 1.0 15.110971260831429 -4.74706972416607 24.97102086720392 0.8971126470333847 1.1221974380312976 0.3638963321043721 0.08952216096458593 847.588773872921 1472822.0462682564 0.021965638206364 0.4670120396519195 1.7903184028156308e-05 4.74706972416607 0.2250847909979129 KPSPQPS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 2 KPSPQPSSPR 10 1 G3V5E1;O75909-1;O75909;O75909-4 G3V5E1 CCNK Cyclin-K 1 KPS(0.001)PQPS(0.5)S(0.5)PR;KPSPQPS(0.906)S(0.094)PR 78.28699999999999 0.0094445 84006000.0 38371.0 32054.0 38032.0 31610.0 31476.0 32239.0 29691.0 27816.0 32389.0 21347.1 True False 37823.8225036204 31979.78093239191 34905.15576776551 33934.70484786883 29624.643564196977 30860.213122779594 31228.254700821257 29108.43290730046 28741.009748709635 25036.917791777236 1.510721999336624 1.277305026056158 1.3941474768603208 1.3553866785876436 1.1832384405530327 1.2325883473130577 1.2472883028388349 1.1626204610880821 1.1479452058651132 1.0 14.6117693475622 -1.522878745281884 0.09799717625097516 0.8442173672089975 2.58004307449744 0.8207734443733228 0.05772375408474375 54.488903948858194 0.3810169242666469 0.7904789211172083 12.70883467402393 0.02999999999989318 1.522878745281884 1.7358257072884427 KPSPQPSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 KPSPQPSSPR 10 1 G3V5E1;O75909-1;O75909;O75909-4 G3V5E1 CCNK Cyclin-K 1 KPS(0.078)PQPS(0.153)S(0.769)PR;KPSPQPS(0.011)S(0.989)PR 78.28699999999999 0.0094445 40665300.0 80328.0 79824.0 104378.0 137000.0 119253.0 103494.0 85310.0 101138.0 86560.0 88776.0 True False 105870.63307380467 105625.5469566015 102993.87952062629 105416.76662890035 102696.77940661782 97022.50381936025 92902.42473263147 85509.44602003359 91135.38488425771 85667.97926131138 1.235825030387019 1.2329641467836416 1.2022447641313687 1.230527059677101 1.1987767225530535 1.1325410574167318 1.084447485906642 0.9981494457713982 1.0638208776498534 1.0 16.386468438106917 -7.118837151965412 1.2346250219115977 1.0185715589197524 1.2270060837509897 0.9455269118777317 0.021131273836209587 0.09164629527894644 0.27939601689217475 0.012046444836496266 0.007825610226309822 7.606114310509246e-08 7.118837151965412 0.20843452483123737 KPSPS(ph)ESPEPWKPFPAVSPEPR ddPTM_PC-9_AZD4547_30min_R2 1 KPSPSESPEPWKPFPAVSPEPR 22 2 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 KPS(0.351)PS(0.606)ES(0.043)PEPWKPFPAVSPEPR 66.308 0.00088344 14346000.0 17485.0 19047.0 18047.0 27489.0 25422.0 24660.0 16076.0 31145.0 19408.0 27790.0 True False 23044.866289406837 25203.57026561421 17807.68498829967 21151.835750816354 21892.59411566196 23118.00630167377 17506.732856661412 26332.255890901048 20433.867257782706 26817.080558617687 0.8593353866031235 0.9398327387100691 0.6640426406362552 0.788744908476594 0.8163675411202342 0.8620627532941793 0.6528202359087747 0.9819210496587467 0.7619721025604432 1.0 14.71086456634969 -10.05579500524838 0.6299961601416472 1.0223586782614595 0.8102227968347747 0.23194735098015018 0.10042502454742532 18.94226791426536 5.745579055250124 1.064063130416216 0.03826939053309949 8.794375290963835e-11 10.05579500524838 -0.21213588142668482 KPSPS(ph)ESPEPWKPFPAVSPEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPSPSESPEPWKPFPAVSPEPR 22 2 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 KPS(0.226)PS(0.732)ES(0.042)PEPWKPFPAVSPEPR 55.336999999999996 0.004227399999999999 10251000.0 16939.0 19254.0 16975.0 23745.0 26215.0 21380.0 14238.0 22113.0 18078.0 17675.0 True False 19806.438139499915 21165.40987474697 17379.748378045988 22414.64463232868 21078.358935952092 20258.795162661056 12889.273565806656 21532.55718066019 18342.35654978411 20879.337584776975 0.9486142967457307 1.0137012148401954 0.8323898355241633 1.0735323638174752 1.009531976307535 0.9702795924632995 0.61732195829834 1.0312854559312972 0.8784932220817883 1.0 14.34978832142292 -7.0476457249499385 24.99998919019223 0.8714421010641721 0.9766377470074654 0.1265431346816882 0.11838110839430727 776.7191538830857 407546.65707050834 0.04407655205717081 0.034142430000318365 8.960954559577261e-08 7.0476457249499385 0.10519564594329334 KPSPSES(ph)PEPWKPFPAVSPEPR ddPTM_PC-9_AZD4547_30min_R2 1 KPSPSESPEPWKPFPAVSPEPR 22 2 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 KPS(0.015)PS(0.107)ES(0.878)PEPWKPFPAVSPEPR 52.464 0.007821 8473000.0 18760.0 17519.0 19381.0 26443.0 20893.0 16636.0 19044.0 24967.0 17014.0 20685.0 True False 24725.289767759346 23181.674147282803 19123.995276679558 20346.97489027746 17992.36758943141 15595.74829013158 20738.87910688355 21108.923834584235 17913.325305230588 19960.82444602399 1.2386908083190118 1.1613585505933537 0.9580764225642432 1.019345415581288 0.9013839903298845 0.7813178424720882 1.0389790844042286 1.0575176336861645 0.8974241196133937 1.0 14.284883689384264 -5.1485465370270465 2.2823913780767353 0.9524793387321726 1.2445249802467597 0.6146290276845348 0.077968301712137 0.24182277772453697 2.2481394382029194 0.022660685747626214 0.10195565035499965 7.103190513566956e-06 5.1485465370270465 0.2920456415145871 KPSPSES(ph)PEPWKPFPAVSPEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPSPSESPEPWKPFPAVSPEPR 22 2 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 KPS(0.013)PS(0.096)ES(0.831)PEPWKPFPAVS(0.06)PEPR 47.485 0.017089 5730200.0 37471.0 32404.0 32798.0 38090.0 38957.0 32063.0 44530.0 41395.0 27466.0 32620.0 True False 43814.10021401506 35620.854969424574 33580.02870710766 35955.94078944618 31323.65550516445 30381.559836314373 40311.79603071854 40308.42511162796 27867.638289433 38533.74778022209 1.1370318938066848 0.9244067089603832 0.8714446593316577 0.9331026142206961 0.8128888911563825 0.7884403045765529 1.046142624398685 1.0460551447403397 0.7232008277102079 1.0 15.233834888438045 -4.763860914284034 4.523247215081693 0.9028681277800177 1.1559794890199042 0.315715927014691 0.10288100363060834 0.2514561190995999 11.455139814085735 0.025947471110513192 0.20717967696535694 1.722420103237773e-05 4.763860914284034 0.25311136123988653 KPSPSES(ph)PEPWKPFPAVSPEPR ddPTM_PC-9_Lapatinib_30min_R1 1 KPSPSESPEPWKPFPAVSPEPR 22 2 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 KPS(0.004)PS(0.096)ES(0.896)PEPWKPFPAVS(0.004)PEPR 59.792 0.0026085 7747800.0 25762.0 17822.0 17596.0 18385.0 16922.0 21404.0 16751.0 15764.0 21829.0 14900.0 True False 25394.6291558278 17780.734253980427 16149.32480252424 19737.094230562114 15926.681229932045 20488.60081516098 17618.284816727522 16496.452989311343 19370.388150439434 17475.445146997972 1.453160645821387 1.0174696040309392 0.9241152180491642 1.1294186823019303 0.9113748517397863 1.1724222555029233 1.0081737356918823 0.9439789859742254 1.1084346056710885 1.0 14.093041584974879 -4.76099352554636 24.999999914979796 1.0229889585126104 1.4531611307984844 0.7025096975315563 0.08379338127853597 5.567108962146927 311817.8073268947 0.019525076080504782 0.11163196798305118 1.733829845462885e-05 4.76099352554636 0.430172172285874 KPSQTAS(ph)YER ddPTM_PC-9_AZD4547_30min_R2 1 KPSQTASYER 10 1 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 KPS(0.001)QT(0.005)AS(0.994)YER 89.46 0.013713 17900000.0 22456.0 18853.0 33744.0 48976.0 45135.0 41650.0 35282.0 49974.0 42036.0 47217.0 True False 29596.540886183582 24946.863559491 33296.5325120621 37685.33987165711 38868.78433681075 39045.618915843974 38422.02964970935 42251.66658827705 44257.93714180513 45563.94720173629 0.6495605122871303 0.5475132224396124 0.7307648822574634 0.8270868128435774 0.8530600776249163 0.8569410973761306 0.8432550735693332 0.9273047921244842 0.9713367664537765 1.0 15.47560511258541 -4.477284000010496 0.29125899188388066 0.9983163171286754 0.15015677928649865 0.8746937767247449 0.04764010845851207 3.261960305547034 0.19850465019797275 0.05816745709608287 1.0195989822360352 3.332084451079061e-05 4.477284000010496 -0.8481595378421768 KPSQTAS(ph)YER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPSQTASYER 10 1 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 KPSQT(0.001)AS(0.999)YER 98.368 0.007031100000000001 4783200.0 8870.9 7696.5 16839.0 15634.0 18766.0 15414.0 14193.0 15539.0 17320.0 14479.0 True False 10372.568161738578 8460.55765560351 17240.505622263117 14758.077666111869 15088.937012858169 14605.66270520381 12848.536291578448 15131.117714931443 17573.272233779222 17103.928084299074 0.6064436257341554 0.49465582490200394 1.0079851562337554 0.862847270719021 0.8821913269566065 0.8539361621036865 0.7512038303863686 0.8846574681766456 1.0274407228074698 1.0 14.0620400717334 -5.255564806339523 24.99939667137999 0.8944864970195291 0.5505496936022222 0.7405516493388798 0.08447676195462246 236.37849574608856 1005907.4911563046 0.02192309405819157 0.05482359172290887 5.551817655428547e-06 5.255564806339523 -0.3439368034173069 KPSQTAS(ph)YER ddPTM_PC-9_Lapatinib_30min_R1 1 KPSQTASYER 10 1 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 KPS(0.02)QT(0.011)AS(0.967)Y(0.002)ER 92.906 0.010479 16456000.0 25783.0 27399.0 28255.0 25614.0 28856.0 25387.0 22441.0 17906.0 25200.0 18684.0 True False 25415.32969197688 27335.559298889555 25931.982967454096 27497.739005799172 27158.746813078786 24301.257189987446 23602.88517534371 18737.978129066792 22361.71063223572 21913.504505134926 1.1598021524134299 1.2474298345334993 1.1833790876022379 1.2548307368798866 1.2393611805320668 1.1089626118128666 1.0770931308505636 0.8550881546434519 1.0204534207203493 1.0 14.419532604538187 -7.248813472659289 1.8535950612933871 0.9568273700113115 1.2171290247092528 0.7912943240873169 0.05603163042876875 0.14119164222924127 0.947249123715792 0.02766029422965022 0.01748606330670605 5.638797874161819e-08 7.248813472659289 0.2603016546979413 KPSVGVPPPAS(ph)PSYPR ddPTM_PC-9_AZD4547_30min_R2 3 KPSVGVPPPASPSYPR 16 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 KPSVGVPPPAS(0.5)PS(0.5)YPR;KPSVGVPPPAS(0.806)PS(0.194)YPR;KPSVGVPPPAS(0.966)PS(0.034)YPR 130.89 5.5824e-06 153115400.0 133721.0 193984.0 278319.0 404392.0 304847.0 284578.0 285737.0 348234.0 280383.0 306713.0 True False 176241.49643041333 256685.5344361267 274628.3082095957 311165.6721941187 262524.25609225093 266783.29267306253 311167.03945408476 294422.4369212407 295203.472966761 295975.0712261718 0.5954606099097344 0.867253898690604 0.927876483218197 1.0513239203052305 0.8869809710819897 0.9013708200755796 1.051328539815787 0.9947541720371962 0.9973930295676111 1.0 18.175116143085255 -4.504245017610839 1.4148185594712075 0.9789204198584217 0.18530976272059033 0.829074124235351 0.052545630034696526 0.9704764558691045 1.0714016646059041 0.015743811268395403 1.3205114404317786 3.1315185048506236e-05 4.504245017610839 -0.7936106571378314 KPSVGVPPPAS(ph)PSYPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KPSVGVPPPASPSYPR 16 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 KPSVGVPPPAS(0.797)PS(0.203)YPR;KPSVGVPPPAS(0.859)PS(0.14)YPR;KPSVGVPPPAS(0.775)PS(0.224)YPR 108.37 0.0003678 119234800.0 197944.3 246035.0 348159.0 358415.0 534480.0 448869.0 432296.0 389869.0 414210.0 358452.0 True False 231452.36041186677 270459.72881133086 356460.43096036057 338334.1695471086 429752.48079678294 425329.51945128595 391345.79332799296 379635.351850351 420267.03764166695 423436.5100955283 0.5466046382246315 0.6387255760026798 0.8418273400183234 0.7990198329161072 1.0149159804378458 1.0044705860515677 0.9242136282478438 0.8965579084446552 0.9925148815033773 1.0 18.691786143080563 -5.200990596404212 0.9473685461229279 0.9648219288300567 0.4510595113005038 0.8877506782810966 0.05172729228080836 0.379761172281487 0.41802129054358117 0.01941484500340448 0.1748760966070858 6.29519813437424e-06 5.200990596404212 -0.5137624175295529 KPSVGVPPPAS(ph)PSYPR ddPTM_PC-9_Lapatinib_30min_R1 2 KPSVGVPPPASPSYPR 16 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 KPS(0.044)VGVPPPAS(0.605)PS(0.35)Y(0.001)PR;KPSVGVPPPAS(0.752)PS(0.242)Y(0.006)PR 119.72 4.767e-05 123218000.0 181325.0 156086.0 139742.0 112546.0 123727.0 117704.0 111624.0 107038.0 144806.0 82644.0 True False 178739.2722490675 155724.59245689533 128252.95217971907 120823.0082824501 116449.6211166412 112670.07430142524 117403.34453957323 112011.37624143019 128496.42340521922 96928.90528379192 1.8440244602551557 1.6065856928948006 1.3231651776548543 1.2465116358087422 1.2013921004853592 1.1623991210005495 1.211231512373275 1.1556034385561178 1.325677031314888 1.0 16.564639337150957 -4.972248201416505 1.1420437052281696 1.1831782016516237 2.045635383400637 0.8951378702430206 0.07530674707218708 0.3302137217041007 0.45321647656618336 0.022299113451132058 0.31619311886556783 1.0659867304916446e-05 4.972248201416505 0.8624571817490132 KPSVSEEVQAT(ph)PNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPSVSEEVQATPNK 14 1 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 KPS(0.431)VS(0.03)EEVQAT(0.539)PNK 121.6 0.00023808 28543000.0 43941.0 41219.0 36654.0 51127.0 58951.0 49755.0 57566.0 73221.0 52690.0 54956.0 True False 51379.343425690175 45310.94991311906 37527.9703710691 48262.51994597047 47399.974733294366 47145.76021132839 52112.93173825161 71299.02633406226 53460.49157031332 64919.08776854332 0.7914366204416406 0.6979603606672147 0.5780729776251317 0.7434257258518684 0.7301392604635785 0.7262233933325996 0.8027366608115377 1.0982752343696727 0.8234941895812916 1.0 15.986355107084051 -7.561448603476167 5.252919176949522 0.9706276539615426 0.7106364861269489 0.6787105547102112 0.08071660928358533 0.10771178506348536 7.324886516498272 0.03797630512734164 0.02185150878114987 2.7450571876912803e-08 7.561448603476167 -0.25999116783459375 KPSVSEEVQAT(ph)PNK ddPTM_PC-9_Lapatinib_30min_R1 1 KPSVSEEVQATPNK 14 1 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 KPSVSEEVQAT(1)PNK 76.357 0.013922 2326800.0 15170.0 22137.0 25024.0 26119.0 19091.0 16413.0 12197.0 12741.0 15282.0 12805.0 True False 14953.673018162719 22085.743136593213 22966.623315433433 28039.87839042979 17968.10491435012 15711.054250571715 12828.500979620658 13332.993373307276 13560.780233405803 15018.327188410001 0.9956949819086923 1.4705860952102112 1.5292397766614994 1.8670440481592934 1.1964118699062922 1.0461254474930008 0.8541897388892097 0.8877815222721118 0.9029487813976366 1.0 13.874436507222823 -6.649183218988744 2.9507955409369186 0.9174373945436773 1.4745187126359627 0.589695540975258 0.20568042225810754 0.18316907852416547 3.2090139873093775 0.07588943307529092 0.07511840525844321 2.242935480563284e-07 6.649183218988744 0.5570813180922853 KPT(ph)SPVKPIPQNTEYR ddPTM_PC-9_AZD4547_30min_R2 1 KPTSPVKPIPQNTEYR 16 2 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 KPT(0.594)S(0.406)PVKPIPQNTEYR 51.643 0.040838 8972600.0 23000.0 23996.0 27407.0 33358.0 23137.0 24533.0 26798.0 30341.0 15440.0 21821.0 True False 30313.521570280624 31752.23773264444 27043.565272584314 25667.828475962455 19924.826923690944 22998.94763175032 29182.97008539515 25652.495616819007 16256.126878615272 21057.053431795488 1.4395899059888484 1.507914572924033 1.28429959871543 1.2189658234520524 0.9462305344965826 1.0922206046655434 1.3858999873804654 1.2182376655835687 0.7720038765760565 1.0 14.362015949970576 -1.5228787452899437 0.2794229662389475 1.0163193415403993 4.930236038931441 0.48136038605892073 0.1597334138926567 50.14273385530152 0.7064420163350729 0.19063461612476537 95.74725513278398 0.02999999999933643 1.5228787452899437 3.9139166973910418 KPTAEAS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 3 KPTAEASPVK 10 1 H3BMJ2;Q6ZRI6-2;Q6ZRI6 H3BMJ2 C15orf39 Uncharacterized protein C15orf39 1 KPT(0.029)AEAS(0.971)PVK;KPTAEAS(1)PVK;KPTAEAS(1)PVK 81.494 0.012877000000000001 69058600.0 113479.0 93773.0 126497.0 142064.0 125419.0 129663.0 119125.0 132504.0 118570.0 130864.0 True False 149562.96149016847 124083.28841903934 124819.56712832849 109313.33966692054 108006.73673952518 121555.15211248705 129726.89422429675 112028.55143900942 124837.36813454743 126282.49119190148 1.1843523205674609 0.9825850539365731 0.9884154640143271 0.865625461100587 0.8552787937592703 0.9625653640912842 1.0272753807743709 0.8871265555631819 0.9885564258060286 1.0 16.946295100722615 -4.531589020020026 1.7390546132611941 0.9394679882190335 1.4224794057811283 0.6102766081344748 0.056452488376071294 1.3528783324234386 2.393417058348394 0.015974981906108375 1.3353480661011894 2.940430913701601e-05 4.531589020020026 0.48301141756209476 KPTAEAS(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPTAEASPVK 10 1 H3BMJ2;Q6ZRI6-2;Q6ZRI6 H3BMJ2 C15orf39 Uncharacterized protein C15orf39 1 KPT(0.06)AEAS(0.94)PVK 69.045 0.018065 16975000.0 41976.0 39416.0 27636.0 47601.0 52215.0 40423.0 42591.0 43545.0 42573.0 45765.0 True False 49081.707736209246 43328.959988730945 28294.94705011363 44934.070294524194 41983.84557851377 38303.14671937546 38556.472147862856 42401.989889741264 43195.54958479692 54061.8322244593 0.9078809525438746 0.8014704312801211 0.5233812078849983 0.8311606996219152 0.7765893949764976 0.7085062629831826 0.7131921091349671 0.7843239517612437 0.7990026939052552 1.0 15.722322787025972 -8.88778461479928 1.3891884735501965 0.9997893680438098 0.7483583202223673 0.37117576729154267 0.09497428129983956 1.5210090608049402 4.412695249833192 0.09220543405013053 0.027144961134894934 1.2948378476837884e-09 8.88778461479928 -0.25143104782144254 KPTAEAS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 4 KPTAEASPVK 10 1 H3BMJ2;Q6ZRI6-2;Q6ZRI6 H3BMJ2 C15orf39 Uncharacterized protein C15orf39 1 KPTAEAS(1)PVK;KPT(0.003)AEAS(0.997)PVK;KPT(0.003)AEAS(0.997)PVK;KPT(0.001)AEAS(0.999)PVK 78.486 0.012054 66232200.0 248775.0 238171.0 219363.0 239790.0 249565.0 257306.0 207417.0 210238.0 225360.0 214832.0 True False 245227.42288025233 237619.52968268248 201327.82090566785 257424.95651599116 234886.07736366833 246301.6221895817 218156.03736082447 220006.42499155278 199977.5836539936 251965.4249543534 0.973258227491642 0.9430640323994062 0.7990295531307156 1.0216677806592982 0.9322155109425065 0.9775215080966059 0.8658173533148292 0.8731611689635974 0.7936707335548994 1.0 17.9428662531258 -7.281140797901916 24.240591337059545 0.8725923997606307 0.9380112150118295 0.12758359028390187 0.07189187184682502 1074.365480668947 1321890.9044254292 0.02941102679980602 0.019863845091756007 5.2343071328279147e-08 7.281140797901916 0.06541881525119875 KPVAGALDVS(ph)FNK ddPTM_PC-9_Lapatinib_30min_R1 1 KPVAGALDVSFNK 13 1 H7C3S9;E9PGT6;Q99627-2;Q99627 H7C3S9 COPS8 COP9 signalosome complex subunit 8 1 KPVAGALDVS(1)FNK 73.833 0.009337799999999999 3360200.0 23781.0 26857.0 24242.0 21113.0 20633.0 23016.0 19999.0 18636.0 21277.0 18381.0 True False 23441.878579098702 26794.814266589154 22248.916336826132 22665.72045090332 19419.407506038766 22031.659332916504 21034.45036414147 19501.89659406282 18880.560203257133 21558.131358857052 1.087379893409348 1.2429098710162854 1.032042896783133 1.0513768597847986 0.9007927070664405 1.02196516786066 0.9757084236106378 0.9046190631940166 0.875797623132125 1.0 14.395944511436479 -5.715181286844353 1.5297000136138823 0.9470344816186078 1.1643286615703528 0.6265085051585966 0.06258970632178727 0.2504916269606538 1.1753873588507675 0.019819078299356693 0.04754600046492278 1.926720477487505e-06 5.715181286844353 0.21729417995174494 KPVIPVLS(ph)STILPSTYQIR ddPTM_PC-9_AZD4547_30min_R2 1 KPVIPVLSSTILPSTYQIR 19 1 Q99570 Q99570 PIK3R4 Phosphoinositide 3-kinase regulatory subunit 4 1 KPVIPVLS(0.845)S(0.097)T(0.058)ILPSTYQIR 143.84 0.00010269 16394000.0 23242.0 29291.0 33281.0 46411.0 39083.0 33492.0 29880.0 39958.0 28485.0 29500.0 True False 30632.472536367954 38758.742933275884 32839.6721945809 35711.66099280213 33657.00007168658 31397.73994548491 32539.262114770023 33783.409243494076 29990.65894671993 28467.21397910116 1.0760614845856145 1.3615221693886208 1.1535962816273386 1.2544838781560916 1.182307481736549 1.102943897795378 1.1430434372207376 1.1867479995863217 1.053515773223793 1.0 14.797013686285693 -8.267512577219309 0.3862707070426065 0.9876898985214997 1.2275808535329245 0.4035563827675198 0.07629119452499898 1.1770951914115493 0.5148343681489458 0.10587316266832185 0.06864452159210535 5.401164727015213e-09 8.267512577219309 0.23989095501142477 KPVTVS(ph)PTTPTSPT(ph)EGEAS ddPTM_PC-9_Lapatinib_30min_R1 1 KPVTVSPTTPTSPTEGEAS 19 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 2 KPVT(0.094)VS(0.513)PT(0.247)T(0.14)PT(0.006)S(0.016)PT(0.811)EGEAS(0.173) 86.016 0.0070179000000000005 0.0 17175.0 20403.0 15811.0 12702.0 17647.0 18152.0 17691.0 17006.0 21254.0 19457.0 True False 16930.081350490746 20355.758107056587 14511.080612224983 13636.147452629864 16609.038155336882 17375.6812743787 18606.95341727219 17796.16084345526 18860.15070545785 22820.116525177164 0.7418928528174686 0.8920093849914535 0.63588985604938 0.5975494225713206 0.7278244235524532 0.7614194807116046 0.8153750396823505 0.7798453098966857 0.8264703944280771 1.0 14.478018537953696 -8.762557730553793 0.6141481230445383 1.003097811682813 0.7232734269119979 0.5361960124586633 0.07549487592514598 1.0025148065702787 0.7936338909861447 0.0918342597335387 0.03562746102341436 1.7275963167073495e-09 8.762557730553793 -0.27982438477081517 KPVTVS(ph)PTTPTSPTEGEAS ddPTM_PC-9_AZD4547_30min_R2 1 KPVTVSPTTPTSPTEGEAS 19 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 KPVT(0.024)VS(0.688)PT(0.227)T(0.061)PTSPTEGEAS 79.837 0.003913000000000001 6445800.0 17881.0 15814.0 20119.0 26955.0 28742.0 22360.0 14634.0 24265.0 20215.0 25258.0 True False 23566.786052095144 20925.566240375032 19852.208914478928 20740.941200598587 24751.669423033443 20961.82566526462 15936.397650185569 20515.40180422903 21283.52363025957 24373.72510793685 0.9668930763652971 0.8585296727401348 0.8144921970919589 0.8509549159494165 1.0155062188246935 0.8600173166980861 0.6538351269497241 0.8417015336547211 0.8732158722561857 1.0 14.573039138778507 -7.002434553833143 24.998288981493566 0.8187008269171189 0.8959314250681606 0.056939791981434396 0.09640478433400451 216.00000424204634 2217934.682068795 0.034500045465542875 0.029919541815209106 9.94409915630826e-08 7.002434553833143 0.07723059815104172 KPVTVSPT(ph)TPTSPTEGEAS ddPTM_PC-9_AZD4547_30min_R2 1 KPVTVSPTTPTSPTEGEAS 19 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 KPVT(0.002)VS(0.027)PT(0.938)T(0.033)PTSPTEGEAS 102.15 0.0012175999999999999 6418500.0 18157.0 15059.0 22877.0 27588.0 25910.0 21775.0 21307.0 21430.0 19284.0 23259.0 True False 23930.548310938513 19926.527255204728 22573.63603243374 21228.012830351105 22312.84373915513 20413.405807743173 23203.281722871656 18118.48591240999 20303.312870933736 22444.70948948861 1.0661999578183783 0.8878050867415679 1.0057441840806853 0.9457913830558906 0.9941248626811038 0.9094974393543946 1.0337973736634152 0.8072497405633745 0.9045923664301495 1.0 14.454087802566708 -7.751221508503263 24.999943392501486 0.8919407721521246 0.9719939834391891 0.19251239905931017 0.06709165302725645 276.5489452106633 676632.7482458545 0.029438025761558503 0.016750270303041513 1.7732848001561636e-08 7.751221508503263 0.08005321128706444 KPVTVSPT(ph)TPTSPTEGEAS ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPVTVSPTTPTSPTEGEAS 19 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 KPVT(0.012)VS(0.174)PT(0.784)T(0.031)PTSPTEGEAS 103.6 0.0058747 0.0 8005.5 7036.9 6684.1 8965.9 9523.1 8355.7 7995.1 9323.3 9200.1 5331.2 True False 9360.673034167688 7735.476926748049 6843.474293590414 8463.569690839991 7657.116917145354 7917.512382630826 7237.746248488613 9078.573253852903 9334.634057620799 6297.704358244018 1.4863627286527172 1.2283010580866522 1.086661726924662 1.343913465826757 1.2158584273842252 1.2572061075344694 1.1492673896344516 1.4415686633445384 1.4822280511471269 1.0 12.620610317316983 -7.762519316993393 24.99990973771687 1.3464237388896263 1.2474866798292412 0.007238376145345726 0.1583790719330131 81.60805515129334 1888990.023926544 0.07767483388811156 0.040613861646190165 1.7277491302088706e-08 7.762519316993393 -0.09893705906038508 KPVTVSPT(ph)TPTSPTEGEAS ddPTM_PC-9_Lapatinib_30min_R1 1 KPVTVSPTTPTSPTEGEAS 19 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 KPVT(0.002)VS(0.05)PT(0.918)T(0.03)PTSPTEGEAS 122.96 0.00010018 11230000.0 35321.0 34880.0 33761.0 30329.0 36271.0 33447.0 30956.0 31545.0 35771.0 23645.0 True False 34817.31606292189 34799.23750302081 30985.300901228715 32559.495834578083 34137.611091529674 32016.54977876512 32558.75021112871 33010.69586068423 31742.093294670784 27732.006745017923 1.2554921244268358 1.2548402220936472 1.1173118911344289 1.1740764429327648 1.230982359315289 1.1544981246089203 1.174049556185757 1.190346452898315 1.1446013837557312 1.0 14.759264396083159 -14.522878745262027 0.16899530434226523 0.2680303085698348 1.2326117634060483 0.7020675592337522 0.03906898146872583 79.51397913512568 0.7457969646783459 19.474599715789736 0.1515899462799965 3.000000000126487e-15 14.522878745262027 0.9645814548362135 KPVTVSPTT(ph)PTSPTEGEAS ddPTM_PC-9_AZD4547_30min_R2 1 KPVTVSPTTPTSPTEGEAS 19 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 KPVTVS(0.001)PT(0.003)T(0.946)PT(0.048)S(0.003)PTEGEAS 117.13 0.00021722 51426000.0 45144.0 41157.0 44294.0 77165.0 67011.0 66336.0 55774.0 81786.0 61491.0 52702.0 True False 59498.85294646737 54460.19538099882 43706.632618814525 59375.80143736565 57707.67934405732 62187.99943340753 60737.77795144522 69147.8529553132 64741.288723635495 50856.91902124033 1.1699264149607205 1.0708512514935007 0.8594038620499308 1.1675068521663183 1.1347065542833175 1.2228031235520735 1.1942874071093093 1.359654778269869 1.2730084710124965 1.0 15.634156443869756 -6.349852282402124 1.7401018891512032 1.231212444677356 1.0428582187778077 0.25225248578334103 0.11610090030546584 0.43331807801121397 2.600393489699599 0.042330667532782716 0.0526445472503364 4.4683554952722756e-07 6.349852282402124 -0.1883542258995483 KPVTVSPTT(ph)PTSPTEGEAS ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPVTVSPTTPTSPTEGEAS 19 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 KPVTVS(0.003)PT(0.045)T(0.755)PT(0.185)S(0.009)PT(0.003)EGEAS(0.001) 72.428 0.019126 35416000.0 16785.0 19907.0 20139.0 21879.0 33554.0 33002.0 32872.0 32682.0 33778.0 26878.0 True False 19626.36898113856 21883.235399220302 20619.19013758281 20653.190562675063 26979.334569404393 31271.317023299354 29758.126187329428 31824.132129441365 34271.9393483022 31750.76863386908 0.6181383892610014 0.6892190753415993 0.6494075899500579 0.650478443556291 0.8497222502079865 0.9848995274382654 0.9372411273088341 1.0023106053405595 1.079405029324038 1.0 14.954503897130275 -6.490064701487358 2.0247737867059517 1.0023662681295702 0.6492042207502671 0.9519517055445491 0.0369165019690591 0.06806636459809536 0.5584393516020159 0.014104737387033583 0.015606584085839481 3.2354545131742435e-07 6.490064701487358 -0.3531620473793031 KPVTVSPTTPT(ph)SPTEGEAS ddPTM_PC-9_AZD4547_30min_R2 3 KPVTVSPTTPTSPTEGEAS 19 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 KPVTVS(0.001)PT(0.004)T(0.285)PT(0.607)S(0.103)PTEGEAS;KPVTVSPT(0.004)T(0.026)PT(0.867)S(0.1)PT(0.002)EGEAS(0.001);KPVTVSPT(0.001)T(0.026)PT(0.849)S(0.122)PT(0.001)EGEAS(0.001) 128.74 0.00011999999999999999 311429000.0 54697.8 46564.6 71015.0 98680.0 87346.0 81727.0 74569.0 102607.0 76539.0 77534.0 True False 72090.56261508242 61615.69632961722 70073.29469962335 75930.85059080202 75219.51560170756 76616.59777035238 81205.49654070562 86751.4458242953 80584.69528253458 74819.55825951273 0.9635256381096938 0.8235239256011413 0.9365638655145905 1.0148529656835816 1.0053456255489717 1.0240183122253488 1.0853511893112648 1.1594755147229905 1.0770538767821294 1.0 16.19112782767968 -6.130434994300288 0.8899071124295403 1.0880748189110283 0.8848493681484382 0.6211493745430804 0.05336644532909934 0.3854663750949872 0.6372221386437628 0.025790716645421576 0.0496480642633172 7.405681082451893e-07 6.130434994300288 -0.20322545076259013 KPVTVSPTTPT(ph)SPTEGEAS ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KPVTVSPTTPTSPTEGEAS 19 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 KPVTVS(0.001)PT(0.006)T(0.024)PT(0.824)S(0.137)PT(0.008)EGEAS;KPVTVS(0.003)PT(0.012)T(0.053)PT(0.704)S(0.145)PT(0.067)EGEAS(0.016) 112.57 0.00035882 42819600.0 41632.0 39816.0 35515.0 41324.0 55304.0 54118.0 58629.0 62894.0 56958.0 43560.0 True False 48679.47533051895 43768.669345223076 36361.81229138753 39008.75025421562 44467.5782030858 51279.956810705815 53075.236682798044 61243.09914170137 57790.90299605058 51457.0831792297 0.9460208842573511 0.8505858987920636 0.7066434792803165 0.7580831995149161 0.8641682632534996 0.996557784515167 1.0314466620257539 1.1901782098372362 1.1230893674007834 1.0 15.651082060443066 -6.93630861086816 1.757475273390622 1.1079346953818645 0.8095651869642507 0.7322845732751992 0.07536421934686603 0.1848735877172227 1.1633891705538697 0.0362533574843505 0.02897694068790809 1.157954218235842e-07 6.93630861086816 -0.2983695084176138 KPVTVSPTTPT(ph)SPTEGEAS ddPTM_PC-9_Lapatinib_30min_R1 3 KPVTVSPTTPTSPTEGEAS 19 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 KPVTVSPT(0.005)T(0.072)PT(0.921)S(0.001)PTEGEAS;KPVTVS(0.004)PT(0.025)T(0.328)PT(0.639)S(0.003)PTEGEAS(0.001);KPVTVS(0.001)PT(0.025)T(0.103)PT(0.432)S(0.432)PT(0.005)EGEAS(0.001) 118.71 0.00018554 233297000.0 173024.0 155496.0 153552.0 117929.0 203092.0 201967.0 211680.0 181218.0 222893.0 179892.0 True False 170556.64603128418 155135.95856564541 140927.54728786115 126601.89205961148 191146.52785423494 193329.3422180723 222639.75464180537 189638.0498488347 197788.44317265533 210986.09250897687 0.8083786187188023 0.7352899744282663 0.6679470936306623 0.6000485176729121 0.9059674293276093 0.9163132030128796 1.0552342668383825 0.898817773217759 0.9374477759203014 1.0 17.68678837891619 -6.407483199539805 5.026502660283561 0.9563704430917356 0.7036944588650397 0.7851587793811713 0.06433043058289621 0.10990329234121235 4.106928670156463 0.021387286880372613 0.024211142903477468 3.9130626431701974e-07 6.407483199539805 -0.2526759842266959 KPVTVSPTTPTS(ph)PTEGEAS ddPTM_PC-9_AZD4547_30min_R2 2 KPVTVSPTTPTSPTEGEAS 19 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 KPVTVSPTTPT(0.042)S(0.773)PT(0.145)EGEAS(0.04);KPVTVSPTT(0.001)PT(0.065)S(0.419)PT(0.419)EGEAS(0.097) 69.805 0.010981 14462500.0 36872.0 32550.0 47299.0 63092.0 59554.0 49482.0 40446.0 54645.0 45542.0 54241.0 True False 48596.529014755964 43071.15095005736 46671.784355382406 48547.11416168309 51285.95507686774 46387.88271773813 44045.615645715836 46200.870867178885 47949.25714416426 52342.03909967545 0.9284416474912857 0.8228787355425063 0.8916692042987641 0.9274975716791306 0.9798234069407079 0.8862452345312959 0.8414959830250278 0.8826723540364585 0.9160754523310417 1.0 15.67568250840018 KPVTVSPTTPTS(ph)PTEGEAS ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KPVTVSPTTPTSPTEGEAS 19 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 KPVTVSPT(0.012)T(0.14)PT(0.046)S(0.799)PT(0.003)EGEAS;KPVTVSPT(0.001)T(0.022)PT(0.127)S(0.798)PT(0.042)EGEAS(0.01) 104.78 0.00037131 54082100.0 38244.0 36740.0 36752.0 42708.0 54782.0 54233.0 55814.0 53820.0 49399.0 43525.0 True False 44717.95384656912 40387.304393798855 37628.30706273618 40315.20922120416 44047.86035587745 51388.9260082599 50526.89386163317 52407.28202700368 50121.366921273635 51415.73795628958 0.8697328021351266 0.7855047111865553 0.7318441504180179 0.7841025107035828 0.856699954269336 0.999478526437713 0.9827126064900197 1.0192848359301396 0.9748253922540927 1.0 15.649922404264624 -6.628401257862307 2.918750731421739 0.99723842797656 0.7891160291386996 0.8906474616754639 0.033751271494882176 0.08233196055363558 1.413897100639368 0.012595460637110941 0.012607532623403053 2.3528743872158693e-07 6.628401257862307 -0.20812239883786043 KPVTVSPTTPTSPT(ph)EGEAS ddPTM_PC-9_AZD4547_30min_R2 1 KPVTVSPTTPTSPTEGEAS 19 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 KPVTVSPTTPT(0.012)S(0.388)PT(0.554)EGEAS(0.046) 96.82 0.0021747 6431000.0 40747.0 35619.0 41746.0 75986.0 50415.0 57861.0 45282.0 53385.0 39187.0 53418.0 True False 53703.698409748904 47132.14518249134 41192.42076364815 58468.601671997174 43415.74747624489 54242.94252316085 49312.01027714247 45135.5749152593 41258.34481815392 51547.85207917377 1.0418222339752181 0.9143377130457303 0.7991103237508242 1.134258738505605 0.8422416400505194 1.052283273410648 0.9566258978434794 0.8756053471623672 0.8003892141768408 1.0 15.653624693480673 -7.75366807777448 9.193790498667635 0.8784079635254127 0.9602174886162415 0.08428514253012542 0.10406513536646775 0.2990722280533186 245.42072470544886 0.04956451229332487 0.026874168529906237 1.763323202735506e-08 7.75366807777448 0.08180952509082873 KPVTVSPTTPTSPT(ph)EGEAS ddPTM_PC-9_Lapatinib_30min_R1 1 KPVTVSPTTPTSPTEGEAS 19 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 KPVTVS(0.001)PT(0.01)T(0.07)PT(0.138)S(0.07)PT(0.639)EGEAS(0.07) 99.45100000000001 0.0017026 124870000.0 44175.0 36376.0 37805.0 34223.0 51396.0 48503.0 52042.0 49567.0 50873.0 47719.0 True False 43545.05639929715 36291.7736069348 34696.81883152015 36739.873584581306 48372.988328423795 46428.63975601537 54736.48011653835 51870.063773229835 45143.14702356063 55967.16556842933 0.7780464841667916 0.6484475895525202 0.6199495450434669 0.6564540692999826 0.8643101332205154 0.8295692534089207 0.9780105810363711 0.9267945454520098 0.8066005588288279 1.0 15.772293064500857 -6.364024368163419 2.919844824608846 0.905494105598397 0.6682312135827927 0.7269626151872894 0.06775212142143376 0.14387895204772516 2.370401926197063 0.022572630328882053 0.026388193616045386 4.324895634643299e-07 6.364024368163419 -0.23726289201560435 KPVTVSPTTPTSPTEGEAS(ph) ddPTM_PC-9_Lapatinib_30min_R1 1 KPVTVSPTTPTSPTEGEAS 19 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 KPVTVSPTTPT(0.005)S(0.063)PT(0.383)EGEAS(0.548) 93.766 0.0011739 4799600.0 17315.0 12245.0 11341.0 11393.0 17477.0 15789.0 15383.0 14889.0 15626.0 14968.0 True False 17068.084924817897 12216.64745483056 10408.586757525993 12230.879225933864 16449.037221104034 15113.74127595667 16179.456470402925 15580.797294966796 13866.035330925208 17555.198856393676 0.9722524401141506 0.6958991210960397 0.5929062292413249 0.6967098080737107 0.936989512660133 0.8609268057622819 0.9216333351023421 0.8875318031098353 0.7898535040447656 1.0 14.099610717978777 -6.258353583339398 24.96644682782959 0.8930448431124954 0.7258648620469436 0.36325649097495916 0.10297138554530631 297.3924241773577 2406130.3914696174 0.031528531386148057 0.03896310528493781 5.516281451946295e-07 6.258353583339398 -0.16717998106555187 KPVVDCVVSVPCFYTDAER ddPTM_PC-9_Lapatinib_30min_R1 1 KPVVDCVVSVPCFYTDAER 19 1 A0A087WYC1;P34932;A0A087WTS8 A0A087WYC1 HSPA4 Heat shock 70 kDa protein 4 0 108.75 0.00011233 3232000.0 19840.0 18576.0 23484.0 19404.0 24596.0 23019.0 20126.0 23580.0 21416.0 19940.0 False True 19557.07796178961 18532.988413306033 21553.236170861506 20831.034889846458 23149.311637596533 22034.531029909856 21168.025802725697 24675.61288302219 19003.90455952222 23386.602431620107 0.8362513545510678 0.792461772397016 0.9216061304279164 0.8907251470475093 0.989853558475739 0.9421860697523908 0.9051347182481385 1.0551174739969609 0.8125979228957083 1.0 14.51339466402355 -5.45565838022011 1.71799744090709 0.9478841754083777 0.8092441800405789 0.3728110916111884 0.06415880447665342 0.3967434007699082 2.1949667235707753 0.01786601213791524 0.05743758147146299 3.5022054520391875e-06 5.45565838022011 -0.1386399953677988 KPYCNAHYPK ddPTM_PC-9_AZD4547_30min_R2 1 KPYCNAHYPK 10 1 Q14847;Q14847-2;C9J9W2;F6S2S5;O76041-2 Q14847 LASP1 LIM and SH3 domain protein 1 0 73.233 0.011304 5309900.0 71930.0 65393.0 95014.0 117130.0 93490.0 84681.0 74866.0 99875.0 66143.0 83648.0 False True 94802.243763056 86530.00842018751 93754.05227895535 90127.4881404605 80510.52725486727 79385.88368337518 81528.92896534035 84441.61364918105 69639.18394638922 80719.50898046973 1.1744650699745165 1.0719838303417286 1.161479467146404 1.1165514914401553 0.997411013418664 0.9834782778793015 1.0100275632879092 1.046111587096149 0.862730519870216 1.0 16.3006297780572 -6.257438232366351 4.032656574669235 0.9856415999789799 1.1310551081600009 0.6708134284046254 0.050876635074255924 0.1340927415595892 5.210809030120191 0.015304982439411722 0.018878523798449613 5.527920233277825e-07 6.257438232366351 0.14541350818102095 KPYCNAHYPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KPYCNAHYPK 10 1 Q14847;Q14847-2;C9J9W2;F6S2S5;O76041-2 Q14847 LASP1 LIM and SH3 domain protein 1 0 55.461000000000006 0.035656 5074700.0 71075.0 75404.0 81077.0 90216.0 88309.0 87792.0 88730.0 75130.0 82923.0 79029.0 False True 83106.59370476157 82889.6107923247 83010.18316623494 85161.49000421837 71005.48538146057 83188.03297101684 80324.8520504302 73157.91710681519 84135.59200009664 93356.33210678036 0.8902084286013379 0.8878841844120022 0.8891757130227486 0.912219750737542 0.7605856376217198 0.8910807772082018 0.8604113961820518 0.7836417247320475 0.9012306942807361 1.0 16.51046025941102 -3.895629504519076 20.69998815981476 0.8698420584523224 0.8748743570744327 0.0 0.06383085942019434 0.0 0.0 0.013878887860682317 0.0 0.00012716584911154786 3.895629504519076 0.005032298622110298 KPYCNAHYPK ddPTM_PC-9_Lapatinib_30min_R1 1 KPYCNAHYPK 10 1 Q14847;Q14847-2;C9J9W2;F6S2S5;O76041-2 Q14847 LASP1 LIM and SH3 domain protein 1 0 72.325 0.012243 9503700.0 118070.0 101810.0 107120.0 100460.0 98871.0 98451.0 94254.0 86834.0 99855.0 88979.0 False True 116386.30014861362 101574.26520018779 98313.0070951579 107848.1635247358 93055.60216786491 94240.48023049017 99134.01093163609 90868.62464310195 88608.2783802341 104358.90159293496 1.11525033679056 0.9733167334051771 0.9420663268250961 1.0334352113575433 0.8916882100852308 0.9030420864152733 0.9499334452399738 0.8707318997812613 0.8490725470248993 1.0 16.671194139009863 -1.5228787453297377 0.5301206748290709 0.9088384407512071 8.303253934195546 0.5338265504871323 0.05260839334603977 96.33343386332368 0.9383079539024866 0.027143294259121417 804.492195487375 0.029999999996587562 1.5228787453297377 7.394415493444338 KQALY(ph)LMFDT(ph)S(ph)QES(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 1 KQALYLMFDTSQESPVK 17 1 D6RAA5;Q4VXL8;E7EMZ9;E9PBC6;O95359-6;O95359-1;O95359-5;O95359-3;O95359;H0Y911;Q4VXL4;E9PGB3;O95359-2 D6RAA5 TACC2 Transforming acidic coiled-coil-containing protein 2 4 KQALY(1)LMFDT(1)S(1)QES(1)PVK 43.297 0.044686000000000003 0.0 6377.0 5102.9 15077.0 13500.0 12217.0 11319.0 9006.8 14184.0 10419.0 11757.0 True False 8404.753350159985 6752.312632351697 14877.069128863206 10387.783572920833 10520.880430770285 10611.221140658776 9808.38775151642 11992.188715894701 10969.727069189932 11345.391008552282 0.7408077292201202 0.5951590938788913 1.3112874750326988 0.9155950257765824 0.9273263850350797 0.9352891524549413 0.8645261978298279 1.05700973257377 0.9668884096564702 1.0 13.46981871058513 -5.224315139209321 24.98929338201823 0.9869113039215971 0.6679832767103082 0.5390549720040778 0.12148750553566531 433.1192888116057 291542.55704542686 0.0302928829708614 0.08014332737294556 5.966022141210758e-06 5.224315139209321 -0.3189280272112889 KQAS(ph)FLEAEGGAK ddPTM_PC-9_Lapatinib_30min_R1 1 KQASFLEAEGGAK 13 1 Q8WYP3;Q8WYP3-2 Q8WYP3 RIN2 Ras and Rab interactor 2 1 KQAS(1)FLEAEGGAK 56.906000000000006 0.032782 3453500.0 38791.0 22570.0 32245.0 28190.0 28304.0 22230.0 18110.0 24490.0 33966.0 20482.0 True False 38237.83322660182 22517.740551696654 29593.940569299484 30263.186639083277 26639.214367805016 21279.274720661004 19047.647187089442 25627.894805140506 30140.39140216345 24022.286409450513 1.591764937560599 0.937368748664908 1.231936879982292 1.259796262656229 1.1089375055209145 0.8858138795768253 0.7929156643306019 1.0668382837637944 1.2546845411977952 1.0 14.552085850934084 -6.506417658285488 4.7108070118701235 0.9908080276980719 1.2277806582347643 0.2905530753021742 0.18545917302484916 0.2784526606672139 16.23506837627268 0.06100329852317916 0.06556941500441038 3.115891609296376e-07 6.506417658285488 0.23697263053669249 KQDDS(ph)PPRPIIGPALPPGFIK ddPTM_PC-9_AZD4547_30min_R2 2 KQDDSPPRPIIGPALPPGFIK 21 2 A0A0A0MRI1;Q8IXQ4-4;Q8IXQ4 A0A0A0MRI1 GPALPP1 GPALPP motifs-containing protein 1 1 KQDDS(1)PPRPIIGPALPPGFIK;KQDDS(1)PPRPIIGPALPPGFIK 47.688 0.019045 75109000.0 278236.0 244406.0 295877.0 416120.0 422640.0 349210.0 280750.0 355730.0 296730.0 348630.0 True False 366709.260331678 323405.4598801762 291953.47765740287 320189.9629899121 363963.7312974349 327373.84349584393 305736.20611518325 300760.1023621844 312414.54201369866 336424.5698147141 1.0900192590976432 0.9613015483925321 0.867812591149916 0.9517436944818174 1.0818583538588993 0.9730973087849831 0.9087808488053282 0.8939897063042336 0.9286317648730622 1.0 18.359923547019868 -7.17654175459622 5.961994964793964 0.9242084830532883 0.9841807682668416 0.13875482408632 0.0654454250439743 0.47717390625276035 26.761294798488354 0.02678140955068303 0.020618932771334787 6.659754889986955e-08 7.17654175459622 0.059972285213553356 KQDDS(ph)PPRPIIGPALPPGFIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KQDDSPPRPIIGPALPPGFIK 21 2 A0A0A0MRI1;Q8IXQ4-4;Q8IXQ4 A0A0A0MRI1 GPALPP1 GPALPP motifs-containing protein 1 1 KQDDS(1)PPRPIIGPALPPGFIK 48.376000000000005 0.017671 20068000.0 102130.0 100730.0 99847.0 136550.0 131530.0 114950.0 133140.0 122710.0 124640.0 104540.0 True False 119418.59184055314 110729.80869862143 102227.73115185626 128899.54620107326 105757.64069600515 108921.81964209021 120528.01534987357 119488.992521992 126462.62420428668 123492.2744618152 0.9670126520949156 0.8966537314272236 0.8278066915308608 1.043786315887558 0.8563907431205849 0.8820132280887717 0.9759964003832629 0.9675827337599078 1.0240529195483392 1.0 16.91406126568605 -7.413692676726182 4.414545737115533 0.9929795975149692 0.9113597119656869 0.31561278364491097 0.057833350304261205 0.298447018412739 9.547345791201137 0.025418751973527002 0.01650245743489754 3.857512333328098e-08 7.413692676726182 -0.08161988554928234 KQDDS(ph)PPRPIIGPALPPGFIK ddPTM_PC-9_Lapatinib_30min_R1 2 KQDDSPPRPIIGPALPPGFIK 21 2 A0A0A0MRI1;Q8IXQ4-4;Q8IXQ4 A0A0A0MRI1 GPALPP1 GPALPP motifs-containing protein 1 1 KQDDS(1)PPRPIIGPALPPGFIK;KQDDS(1)PPRPIIGPALPPGFIK 46.876999999999995 0.020665 49585000.0 244241.0 211358.0 211283.0 188156.0 227238.0 198612.0 179121.0 166547.0 206496.0 183772.0 True False 240758.07855168675 210868.6135367964 193912.12731596522 201993.61991001602 213872.30760709717 190117.8277471853 188395.008934216 174285.38162971576 183238.24598072024 215536.74533920226 1.1170163963123423 0.9783418284661421 0.8996708519969291 0.9371655844210106 0.9922777077779212 0.8820668951272611 0.874073739202697 0.808610992781918 0.8501485242915213 1.0 17.71757431961911 -1.5228787453565986 0.6280555029894541 0.8867961009367895 17.857983543896456 0.5614894241492405 0.05675016527019955 148.69800259819667 1.0415743893879073 0.02580346746101428 3490.1728919808343 0.029999999994732074 1.5228787453565986 16.971187442959668 KQEAESWS(ph)PDACLGVK ddPTM_PC-9_AZD4547_30min_R2 2 KQEAESWSPDACLGVK 16 1 E9PFK9;Q9UJ41;Q9UJ41-4;Q9UJ41-3;A0A0A0MSJ3;Q3HKR1 E9PFK9 RABGEF1 Rab5 GDP/GTP exchange factor 1 KQEAES(0.004)WS(0.996)PDACLGVK;KQEAES(0.006)WS(0.994)PDACLGVK 89.507 0.011682 6803300.0 72218.0 68324.0 88471.0 108672.0 97181.0 97758.0 77492.0 95379.0 74816.0 86827.0 True False 95181.82177228374 90408.39685135841 87297.8167340755 83619.34936566318 83689.09561616482 91645.1768061243 84388.63787810439 80640.36714137884 78770.62102010877 83787.2131580821 1.1359946009029245 1.0790237966357 1.041899037379008 0.9979965464169072 0.9988289675927977 1.0937847596532004 1.0071780012409242 0.9624424074021166 0.9401269961263841 1.0 16.35444246928556 -1.5228787452803376 0.3635228460977168 0.9834308825052065 2.905842727857642 0.6118744927375092 0.036178714774044544 49.09605615040766 0.6829457338920704 0.03246659463211254 65.5193811819323 0.029999999999999995 1.5228787452803376 1.9224118453524355 KQEAESWS(ph)PDACLGVK ddPTM_PC-9_Lapatinib_30min_R1 2 KQEAESWSPDACLGVK 16 1 E9PFK9;Q9UJ41;Q9UJ41-4;Q9UJ41-3;A0A0A0MSJ3;Q3HKR1 E9PFK9 RABGEF1 Rab5 GDP/GTP exchange factor 1 KQEAES(0.002)WS(0.998)PDACLGVK;KQEAES(0.011)WS(0.989)PDACLGVK 62.792 0.016513 15569400.0 110235.0 88040.0 101933.0 97079.0 98138.0 92465.0 89607.0 92324.0 109585.0 79260.0 True False 108663.02868537704 87836.14878916138 93552.4622127588 104218.51350605031 92365.71578673157 88510.48749644261 94246.41200958175 96613.71008533267 97242.3833187917 92959.98539268872 1.1689226092964013 0.9448812671185045 1.0063734607698924 1.1211115520920367 0.9936072536646087 0.952135342131884 1.0138384984836089 1.0393042735238136 1.0460671105746515 1.0 16.50432222159334 -4.744339173534706 24.942772207122633 1.0149477126109634 1.1689230814468388 0.49319181375018795 0.04737164445323422 946.532740642728 1380560.0697218035 0.012317800195874045 0.35243349312710415 1.801610177119936e-05 4.744339173534706 0.15397536883587537 KQEGPATQVDSAVGTLPAT(ph)SPQSTSVQAK ddPTM_PC-9_AZD4547_30min_R2 3 KQEGPATQVDSAVGTLPATSPQSTSVQAK 29 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06 E7ETY2 TCOF1 Treacle protein 1 KQEGPATQVDSAVGTLPAT(0.422)S(0.422)PQS(0.047)T(0.047)S(0.062)VQAK;KQEGPATQVDSAVGTLPAT(0.623)S(0.365)PQS(0.001)T(0.008)S(0.002)VQAK;KQEGPATQVDSAVGTLPAT(0.457)S(0.457)PQS(0.029)T(0.043)S(0.013)VQAK 160.04 1.9257e-13 266887000.0 413478.0 360942.0 503793.0 610155.0 588441.0 536196.0 441150.0 538713.0 443577.0 526009.0 True False 544955.4031233258 477609.4428944883 497112.37564750126 469493.1915507786 506746.12438101927 502667.5793565387 480411.4953792098 455467.28424321685 467023.57463960664 507593.5850146797 1.0736057728301778 0.9409288395176936 0.9793511784297366 0.9249391745902399 0.9983304347046941 0.9902953744815381 0.946449107242591 0.8973070142918466 0.9200738315597512 1.0 18.953314310901114 -7.425222389807614 4.756028916331654 0.929839982526215 0.9800164617492177 0.17424073245504101 0.04457400082633283 0.3557244018849352 13.09572792997548 0.018928044750278535 0.012344314342641542 3.7564499794877014e-08 7.425222389807614 0.05017647922300272 KQEGPATQVDSAVGTLPAT(ph)SPQSTSVQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 KQEGPATQVDSAVGTLPATSPQSTSVQAK 29 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06 E7ETY2 TCOF1 Treacle protein 1 KQEGPATQVDSAVGTLPAT(0.462)S(0.462)PQS(0.033)T(0.033)S(0.009)VQAK;KQEGPATQVDSAVGTLPAT(0.556)S(0.341)PQS(0.034)T(0.055)S(0.014)VQAK;KQEGPATQVDSAVGTLPAT(0.442)S(0.442)PQS(0.015)T(0.076)S(0.025)VQAK;KQEGPATQVDSAVGT(0.001)LPAT(0.715)S(0.162)PQS(0.055)T(0.055)S(0.013)VQAK;KQEGPATQVDSAVGT(0.004)LPAT(0.444)S(0.444)PQS(0.026)T(0.057)S(0.024)VQAK;KQEGPATQVDSAVGTLPAT(0.873)S(0.126)PQSTSVQAK 173.86 5.238800000000001e-19 329655300.0 498335.0 493656.0 538195.0 594832.0 631234.0 574586.0 606158.0 598942.0 527344.0 440273.0 True False 582693.2729351002 542662.905221152 551027.6099159034 561505.4915113644 507548.22905118496 544453.6986591567 548738.3260361158 583220.4071315046 535055.4083631664 520091.0097008499 1.120367901129955 1.0433998955938215 1.0594830513083622 1.07962929763838 0.975883488820775 1.0468431264988025 1.0550813526881448 1.1213814433496283 1.0287726539840092 1.0 18.988404574143466 -7.634335231643919 0.00583814896673396 5.4916992988076545e-08 2.097781589349434 0.16075416851599877 0.04039472235580998 8480.907598861333 42.99035405405955 7689.841755941249 7753.451987983219 2.320944569048754e-08 7.634335231643919 2.097781534432441 KQEGPATQVDSAVGTLPAT(ph)SPQSTSVQAK ddPTM_PC-9_Lapatinib_30min_R1 2 KQEGPATQVDSAVGTLPATSPQSTSVQAK 29 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06 E7ETY2 TCOF1 Treacle protein 1 KQEGPATQVDSAVGTLPAT(0.493)S(0.493)PQS(0.004)T(0.007)S(0.002)VQAK;KQEGPATQVDSAVGTLPAT(0.81)S(0.167)PQS(0.006)T(0.006)S(0.009)VQAK 177.12 3.4045e-19 209014000.0 422050.0 364750.0 446330.0 363690.0 425380.0 384580.0 348148.0 328886.0 426530.0 340119.0 True False 416031.48960550915 363905.44378517236 409634.4702836241 390436.97583427385 400359.98472925724 368132.4098997668 366173.39993875346 344167.2442173717 378489.69983998046 398908.1159699198 1.0429256085551304 0.9122537978460512 1.026889285738456 0.97876418203463 1.0036396069701599 0.9228501380692047 0.9179392077507024 0.862773231325592 0.9488142373832299 1.0 18.605696950457634 -6.769890487318203 24.266074837344764 0.9211151551656221 0.9895180401513467 0.3062773074909928 0.045761055208138904 143.2971445598214 411452.7601638955 0.015139802613849606 0.01357563788425284 1.6986719394304218e-07 6.769890487318203 0.06840288498572455 KQEGPATQVDSAVGTLPATS(ph)PQSTSVQAK ddPTM_PC-9_AZD4547_30min_R2 1 KQEGPATQVDSAVGTLPATSPQSTSVQAK 29 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06 E7ETY2 TCOF1 Treacle protein 1 KQEGPATQVDSAVGTLPAT(0.352)S(0.593)PQS(0.018)T(0.018)S(0.02)VQAK 119.29 9.3196e-14 109630000.0 202280.0 190470.0 243690.0 318050.0 290360.0 296340.0 264290.0 295280.0 266680.0 251550.0 True False 266600.8323146248 252035.70265614198 240458.5113757828 244728.48632351664 250048.5259784286 277809.81295369106 287811.29800242925 249651.26085937544 280776.16036198975 242743.31106586056 1.0982829192862549 1.0382807318128746 0.9905875894991898 1.0081780842855748 1.0300944025212955 1.1444591891486409 1.1856610867614843 1.0284578378830824 1.1566792886243946 1.0 17.88907201632199 -6.744881540322097 24.42627035587902 1.109993189156803 1.0296287197470229 0.2564481023297459 0.05883235402629639 229.31880306904688 338292.227511476 0.019095328482735336 0.019040461044154095 1.7993616483589006e-07 6.744881540322097 -0.08036446940978004 KQEGPATQVDSAVGTLPATS(ph)PQSTSVQAK ddPTM_PC-9_Lapatinib_30min_R1 2 KQEGPATQVDSAVGTLPATSPQSTSVQAK 29 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06 E7ETY2 TCOF1 Treacle protein 1 KQEGPATQVDSAVGTLPAT(0.144)S(0.819)PQS(0.004)T(0.024)S(0.008)VQAK;KQEGPATQVDSAVGTLPAT(0.471)S(0.512)PQS(0.005)T(0.005)S(0.007)VQAK 166.65 5.5642e-15 161751000.0 192929.0 166505.0 203913.0 163531.0 189676.0 190221.0 177808.0 155753.0 196201.0 148356.0 True False 190177.7970811541 166119.4679025367 187148.06026694234 175557.615263424 178519.63059736404 182085.6912568088 187014.0282187743 162989.85298428164 174102.77729187612 173999.13692805593 1.0929812666817285 0.9547143212050686 1.0755688997717452 1.0089568164697993 1.0259799775396428 1.0464746806881946 1.0747985968234985 0.9367279393556628 1.0005956372292988 1.0 17.408720624460805 -7.760563866560123 24.999994929670827 0.9764963456280848 1.036543012662858 0.3165414351148651 0.04068620005882284 27.013306913653572 771447.653655722 0.019198346226594866 0.010250114859202396 1.7355460178491792e-08 7.760563866560123 0.06004666703477324 KQELANSSDATLPDRPLS(ph)PPLTAPPTMK ddPTM_PC-9_AZD4547_30min_R2 2 KQELANSSDATLPDRPLSPPLTAPPTMK 28 2 A0A1B0GV05;Q684P5-3;Q684P5-2;Q684P5 A0A1B0GV05 RAP1GAP2 Rap1 GTPase-activating protein 2 1 KQELANSSDATLPDRPLS(0.417)PPLT(0.417)APPT(0.166)MK;KQELANSSDAT(0.009)LPDRPLS(0.898)PPLT(0.087)APPT(0.006)MK 53.551 0.0035589 20061700.0 96405.0 90444.0 104428.0 138554.0 114711.0 117177.0 89836.0 124344.0 113729.0 117897.0 True False 127059.78465143073 119678.25427118251 103043.21648795686 106612.51593796094 98785.35770599106 109849.90366631093 97831.22996460793 105129.49194086377 119740.48275764471 113769.46191505398 1.1168180152447233 1.0519365412885606 0.9057194677152831 0.9370925566789023 0.868294145398606 0.9655482395471854 0.8599076440886542 0.9240572133439353 1.0524835113226518 1.0 16.79575383475172 -5.094248325749541 3.4582116361790796 0.9320563103188138 1.108250264451732 0.5326254376011432 0.05543436389371816 0.1704354045528886 3.706567935571759 0.014186117160199038 0.05022880397225713 8.049180645508006e-06 5.094248325749541 0.17619395413291827 KQELANSSDATLPDRPLS(ph)PPLTAPPTMK ddPTM_PC-9_Lapatinib_30min_R1 2 KQELANSSDATLPDRPLSPPLTAPPTMK 28 2 A0A1B0GV05;Q684P5-3;Q684P5-2;Q684P5 A0A1B0GV05 RAP1GAP2 Rap1 GTPase-activating protein 2 1 KQELANSSDAT(0.003)LPDRPLS(0.808)PPLT(0.167)APPT(0.022)MK;KQELANSSDATLPDRPLS(0.93)PPLT(0.047)APPT(0.022)MK 62.605 0.00026549 15559700.0 84798.0 73372.0 78940.0 75929.0 96253.0 91642.0 86014.0 73854.0 92190.0 80478.0 True False 83588.76496995117 73202.11164196237 72449.85791721195 81513.07195171862 90591.58778067896 87722.68528793589 90467.38405026564 77285.52645728223 81806.59139626229 94388.51506980567 0.8855819472118247 0.7755404520118285 0.7675706929347407 0.8635909982420539 0.9597734185528964 0.9293788044346284 0.9584575409768855 0.8188022282173334 0.8667006927247628 1.0 16.52632370672295 -5.992055031022882 6.008420644674297 0.9151959575415387 0.8069379214010131 0.4456591047516596 0.05624498840344489 0.15213623213228344 21.638883948060002 0.016741014764075208 0.024019797658941792 1.0184623268363065e-06 5.992055031022882 -0.10825803614052565 KQELEEICHDLEAR ddPTM_PC-9_AZD4547_30min_R2 2 KQELEEICHDLEAR 14 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 137.73 7.688e-06 29145000.0 168572.0 179508.0 225195.0 296790.0 265740.0 224383.0 190001.0 251475.0 186885.0 210420.0 False True 222174.38948458014 237530.45052973594 222208.76716020095 228369.65085979097 228846.58800629407 210352.2955388668 206910.72091929076 212615.31707061603 196763.35956671086 203053.2598468634 1.0941680505505664 1.1697938299974804 1.0943373542871662 1.1246785746361345 1.1270274024602374 1.0359464098114364 1.0189972870927388 1.0470913750952042 0.969023396694561 1.0 17.631498663123097 -6.834917427621875 3.7228101291750275 1.014248189029216 1.1238066756212772 0.8008118680694032 0.02704594368428431 0.09929013901848957 2.7152585013333606 0.00950887579046501 0.00849671372493662 1.4624552045261876e-07 6.834917427621875 0.10955848659206113 KQELEEICHDLEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 KQELEEICHDLEAR 14 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ;;; 116.58 5.657e-05 35112700.0 178108.0 185281.0 199223.0 223434.0 247912.0 212125.0 215880.0 212679.0 208378.0 162186.0 False True 208258.16660665063 203674.47320052944 203973.23187743445 210915.71736280125 199335.42325118306 201000.79157527967 195430.2835641479 207096.401602027 211425.13403755496 191589.03793633042 1.087004605534163 1.0630799934817527 1.0646393659809472 1.1008757058057441 1.0404322992499546 1.0491246980533249 1.0200494019344364 1.0809407669286906 1.103534608842373 1.0 17.547655491840118 -6.281243567620797 24.96592976151938 1.0516180096911876 1.076751315683932 0.1994214227022647 0.028927860559388802 1683.922083212919 2122814.33228813 0.00915262638930672 0.010386439514563514 5.233068653746532e-07 6.281243567620797 0.025133305992744326 KQELLEALTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KQELLEALTK 10 1 P12956;B1AHC9;P12956-2 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 ; 95.417 0.014980000000000002 0.0 51830.0 49518.0 47115.0 52957.0 61447.0 54445.0 58547.0 48789.0 54673.0 43467.0 False True 60603.79531083776 54433.81978693877 48238.40028463251 49989.99097891051 49406.90145098028 51589.80835505525 53001.00431642665 47508.34044621851 55472.489193845875 51347.22301541736 1.1802740586894263 1.0601122434721473 0.9394549004168852 0.9735675669140017 0.9622117526423097 1.0047244101120143 1.0322078041204437 0.9252368026203444 1.0803405897372458 1.0 15.6479986336933 -4.880633935693249 3.0713142035843553 0.987721720747783 1.1909697975982902 0.6487834887543207 0.042943710676176666 0.17310405895290404 2.7218002203742317 0.01049036800263889 0.07646254880779069 1.3163338949413984e-05 4.880633935693249 0.20324807685050728 KQELLEALTK ddPTM_PC-9_Lapatinib_30min_R1 1 KQELLEALTK 10 1 P12956;B1AHC9;P12956-2 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 87.719 0.024798 0.0 27093.0 22920.0 25024.0 21274.0 23835.0 23933.0 23854.0 22980.0 23845.0 23154.0 False True 26706.64885175229 22866.930148200605 22966.623315433433 22838.56092798358 22433.072161412972 22909.44138054791 25089.043401481602 24047.73469261447 21159.325001018296 27156.138049234323 0.9834479705226455 0.8420538335290038 0.8457249434288019 0.8410091628852772 0.8260774091198686 0.8436192708629219 0.9238811261010288 0.8855358832325757 0.7791728324055597 1.0 14.728990704000404 -7.228689080862708 24.576585029709168 0.8876088266753855 0.8591210532131334 0.0484540857771778 0.06580142558345661 2050.435160459597 1538697.1706783082 0.0247005892003329 0.019131221294652955 5.906237668998159e-08 7.228689080862708 -0.028487773462252175 KQEVQAWDGEVR ddPTM_PC-9_AZD4547_30min_R2 1 KQEVQAWDGEVR 12 1 P45974-2;P45974 P45974-2 USP5 Ubiquitin carboxyl-terminal hydrolase 5 0 79.744 0.009523299999999998 4322300.0 40887.0 47434.0 59619.0 78915.0 68682.0 57184.0 64298.0 64602.0 61136.0 61073.0 False True 53888.21549756801 62766.112877573614 58828.413105637446 60722.36597459619 59146.68983761682 53608.27544018302 70020.3974382691 54619.24530627673 64367.52414838229 58934.85285917443 0.914369220982609 1.0650083920215094 0.9981939421518312 1.0303303228684229 1.0035944261869725 0.9096192293595889 1.1880982821079356 0.9267732531171343 1.0921809595790337 1.0 15.846833446139584 KQEVQAWDGEVR ddPTM_PC-9_Lapatinib_30min_R1 1 KQEVQAWDGEVR 12 1 P45974-2;P45974 P45974-2 USP5 Ubiquitin carboxyl-terminal hydrolase 5 0 104.94 0.0034571 0.0 45723.0 39488.0 37302.0 39413.0 35222.0 40323.0 39538.0 35747.0 48114.0 34287.0 False True 45070.9816354287 39396.56796213548 34235.17354988399 42311.56349791377 33150.31120911635 38598.479287504015 41585.08417908023 37407.93612083942 42694.89465711864 40213.46226544431 1.1207933636233678 0.9796860489674675 0.8513361352449998 1.0521741007680498 0.8243585441684943 0.9598397430372948 1.0341085257613982 0.9302341557639096 1.0617065095090468 1.0 15.29539093300066 -7.152874770947959 9.867665478108842 1.000652601144282 0.9577025302345157 0.04789815550590937 0.08654976988619653 1.4253296250315648 120.22691273688208 0.03282480419659561 0.025423811905603038 7.032750804045126e-08 7.152874770947959 -0.042950070909766325 KQFS(ph)LENVQEGEILHDAK ddPTM_PC-9_AZD4547_30min_R2 2 KQFSLENVQEGEILHDAK 18 1 O75113 O75113 N4BP1 NEDD4-binding protein 1 1 KQFS(1)LENVQEGEILHDAK;KQFS(1)LENVQEGEILHDAK 86.772 0.00062705 8101800.0 30233.0 32184.0 38726.0 59942.0 55191.0 47383.0 43743.0 45041.0 44057.0 43966.0 True False 39846.46511453456 42586.84860757746 38212.46793688113 46123.29799466819 47528.6823160058 44420.13351955426 47636.04225858048 38080.94838921411 46385.76307585188 42426.76372220886 0.9391822901089294 1.0037732051970019 0.9006689312217867 1.0871274155309736 1.1202523630414514 1.0469837815204828 1.1227828398715396 0.8975690118282608 1.0933137247885496 1.0 15.37268701481284 -5.768273037225224 24.999892394804014 1.0538198122029296 0.9534646449130623 0.3388234862527111 0.06687174851813493 184.5361572380498 675099.5531917714 0.01872512675027019 0.02848485639463447 1.7050101266977028e-06 5.768273037225224 -0.10035516728986738 KQFS(ph)LENVQEGEILHDAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KQFSLENVQEGEILHDAK 18 1 O75113 O75113 N4BP1 NEDD4-binding protein 1 1 KQFS(1)LENVQEGEILHDAK 49.993 0.033007999999999996 3336500.0 11081.0 7498.7 10399.0 10898.0 13949.0 13690.0 14693.0 11164.0 7926.3 9792.8 True False 12956.794440273841 8243.12137881817 10646.951598427118 10287.420391792715 11215.793583734345 12972.072300132359 13301.172671891925 10870.956829235762 8042.207142413634 11568.157120237855 1.120039631689186 0.7125699705787435 0.9203671326179398 0.8892877478120901 0.9695402186501194 1.1213603139464998 1.1498091298070507 0.9397310838921457 0.6952021016678823 1.0 13.497871431958776 -4.473577911987347 22.311691930866086 0.9416560818733677 3.365697772663618 0.13564509427376714 0.1400793412308027 465.23450527738777 292213.9190449582 0.035886737100698285 20818.65900511876 3.3606407408647044e-05 4.473577911987347 2.4240416907902502 KQFS(ph)LENVQEGEILHDAK ddPTM_PC-9_Lapatinib_30min_R1 2 KQFSLENVQEGEILHDAK 18 1 O75113 O75113 N4BP1 NEDD4-binding protein 1 1 KQFS(1)LENVQEGEILHDAK;KQFS(1)LENVQEGEILHDAK 72.92699999999999 0.0027695999999999997 14552900.0 73970.0 47038.0 58701.0 52095.0 62300.0 65895.0 61112.0 60623.0 73256.0 73846.0 True False 72915.17423556332 46929.086401006134 53874.83037241275 55926.24008382556 58635.63648651259 63076.82445874758 64276.08033668752 63439.76589514218 65005.13786012143 86610.18270639029 0.8418776171243831 0.5418425978859366 0.6220380639889557 0.645723612816016 0.6770062670955008 0.7282841634519913 0.7421307556247089 0.7324746803756766 0.7505484439455548 1.0 16.40224903124971 -9.654406921440584 0.34489984035568055 1.0781043771708276 0.6472057909850377 0.6273797993450554 0.07297906277807625 3.570527598155746 0.5495774560907969 0.43978561808503064 0.06535876241466448 2.2161190069333406e-10 9.654406921440584 -0.4308985861857899 KQGGLGPMNIPLVSDPK ddPTM_PC-9_Lapatinib_30min_R1 1 KQGGLGPMNIPLVSDPK 17 1 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 126.07 5.4466e-05 0.0 62446.0 71892.0 72516.0 68552.0 69569.0 64379.0 70067.0 60807.0 63831.0 67768.0 False True 61555.5085888061 71725.53849103127 66554.014399855 73593.54276276834 65477.08819791654 61625.66024477891 73694.72641953602 63632.315206867264 56641.68060977139 79481.60850481612 0.7744622906703782 0.9024167960401195 0.8373511262774989 0.9259191421410276 0.8238017502369622 0.7753449056210879 0.9271921870462718 0.8005916891202765 0.7126388314894161 1.0 16.27833344889647 KQGGS(ph)PDEPDSK ddPTM_PC-9_AZD4547_30min_R2 3 KQGGSPDEPDSK 12 1 V9GZ50;Q9ULX6;Q9ULX6-2 V9GZ50 AKAP8L A-kinase anchor protein 8-like 1 KQGGS(1)PDEPDSK;KQGGS(0.712)PDEPDS(0.288)K;KQGGS(1)PDEPDSK 85.90899999999999 0.013822999999999998 19621500.0 80521.2 66583.7 65159.7 91457.1 87369.7 85656.3 79459.0 61733.8 80998.0 99925.0 True False 106125.2666549947 88105.57890977997 64295.63980340831 70373.07859310956 75239.9252657994 80300.19802019687 86530.69706752028 52194.2597115976 85279.38891930561 96426.65616480293 1.1005801805842552 0.9137056330066927 0.6667828415984948 0.7298093845838108 0.7802813895901018 0.8327593345449591 0.897373200618204 0.541284555407504 0.884396413928888 1.0 16.557144399456938 -4.922824499686007 3.443377149014538 0.7778393457446783 1.1009322836841129 0.3725759004622995 0.12243328175439776 0.24508417558879442 5.3083322140444675 0.029850656206351696 0.16998769899545668 1.194470697821458e-05 4.922824499686007 0.3230929379394346 KQGGS(ph)PDEPDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KQGGSPDEPDSK 12 1 V9GZ50;Q9ULX6;Q9ULX6-2 V9GZ50 AKAP8L A-kinase anchor protein 8-like 1 KQGGS(0.989)PDEPDS(0.011)K;KQGGS(1)PDEPDSK;KQGGS(1)PDEPDSK 91.59200000000001 0.0028975999999999997 25864300.0 80856.0 99289.0 73123.0 91362.0 130151.0 114516.0 87470.0 110846.0 110723.0 89671.0 True False 94543.32382120554 109145.7557418591 74866.52964052166 86243.28333960065 104648.84584677118 108510.57936610338 79184.20837204017 107936.40995104531 112342.11440766392 105927.64246475448 0.8925274047580464 1.0303802973636027 0.7067704699029072 0.8141716489942326 0.987927640149182 1.0243839742039793 0.7475311120833006 1.018963581550106 1.0605552223542003 1.0 16.69271959297337 -7.961878981251461 24.848684999568896 1.0334384500923761 0.8907572761030159 0.27470605432513906 0.1043453793874147 197.5887641177733 128795.40348057229 0.05873409188700566 0.028214852689020357 1.0917445151890746e-08 7.961878981251461 -0.1426811739893602 KQGGS(ph)PDEPDSK ddPTM_PC-9_Lapatinib_30min_R1 2 KQGGSPDEPDSK 12 1 V9GZ50;Q9ULX6;Q9ULX6-2 V9GZ50 AKAP8L A-kinase anchor protein 8-like 1 KQGGS(1)PDEPDSK;KQGGS(1)PDEPDSK 116.79 0.00097065 16953700.0 55455.0 58726.0 49128.0 58717.0 58349.0 52715.0 56380.0 63656.0 62130.0 49612.0 True False 54664.2015307985 58590.02355511467 45088.88547956414 63035.24405417 54917.02653854775 50460.502334666904 59299.08053054134 66613.6901476532 55132.265142095435 58187.368096165366 0.9394513503421535 1.0069199806096032 0.7748913029550749 1.083314920688501 0.9437963656955102 0.8672071617205922 1.0191057349859622 1.144813596613646 0.9474954263437245 1.0 15.828418371806723 -7.501041312985988 23.112406523962683 1.044084610186631 0.9392490844130076 0.200319692436409 0.08886945763411153 417.7354703437206 442127.91379637824 0.036326549123130464 0.024190925724022302 3.154704512579086e-08 7.501041312985988 -0.10483552577362343 KQIT(ph)MEELVR ddPTM_PC-9_Lapatinib_30min_R1 1 KQITMEELVR 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 KQIT(1)MEELVR 55.083999999999996 0.042268 20496000.0 225780.0 138360.0 204430.0 227260.0 163700.0 170350.0 139520.0 122100.0 238110.0 224820.0 True False 222560.33579701892 138039.63592081293 187622.55452262075 243973.45851713637 154071.4878465831 163064.5276052454 146743.6629233972 127773.21174796477 211291.54439054168 263679.83744618075 0.8440551919046345 0.5235122914886807 0.7115544227416177 0.9252639901484063 0.5843127382768899 0.6184186443096099 0.5565221229831379 0.48457710299538675 0.8013185476635771 1.0 18.008427732675628 -8.529012433091298 21.50841503051477 1.0000000176928516 0.6546915105416077 0.3984234275329398 0.13204335710880427 105.35092682520936 369427.8333613014 0.13062999324381938 0.033728519201587676 2.9579277850412803e-09 8.529012433091298 -0.34530850715124395 KQLVIYEEIS(ph)DPEEDDE ddPTM_PC-9_AZD4547_30min_R2 4 KQLVIYEEISDPEEDDE 17 1 Q16385;Q99909;Q7RTT5;Q7RTT3;Q16384 Q16385 SSX2;SSX3;SSX7;SSX9;SSX1 Protein SSX2;Protein SSX3;Protein SSX7;Protein SSX9;Protein SSX1 1 KQLVIYEEIS(1)DPEEDDE;KQLVIYEEIS(1)DPEEDDE;KQLVIYEEIS(1)DPEEDDE;KQLVIYEEIS(1)DPEEDDE 87.932 0.0071166 4652000.0 68550.0 56098.8 80856.0 114260.0 97141.0 73887.0 66900.6 85261.0 71711.0 82521.0 True False 90347.47407142355 74231.64002817449 79783.79660962803 87919.12229940263 83654.64892571456 69266.8342097231 72854.62379636483 72085.87155286937 75501.49705909197 79631.96490743737 1.1345629129764871 0.9321839554563282 1.0019066677855701 1.1040682268935356 1.0505159457380346 0.8698370596561006 0.9148917006010038 0.9052378857743943 0.9481305295788371 1.0 16.281060035903998 -6.7492462078536235 24.959173239651868 0.9209013193403021 1.039326244920755 0.4837070984334152 0.06012779106277676 193.40399917967227 395893.34335404995 0.019901070208981297 0.019760544383138547 1.7813685973876646e-07 6.7492462078536235 0.11842492558045292 KQLVIYEEIS(ph)DPEEDDE ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KQLVIYEEISDPEEDDE 17 1 Q16385;Q99909;Q7RTT5;Q7RTT3;Q16384 Q16385 SSX2;SSX3;SSX7;SSX9;SSX1 Protein SSX2;Protein SSX3;Protein SSX7;Protein SSX9;Protein SSX1 1 KQLVIYEEIS(1)DPEEDDE;KQLVIYEEIS(1)DPEEDDE 88.76799999999999 0.0068881 0.0 18894.4 21815.0 25091.8 29023.0 28228.0 27680.0 26185.6 29469.0 23593.6 19425.9 True False 22092.848738589462 23980.649029687596 25690.083673181427 27396.935403835556 22696.92603639351 26228.412072144904 23705.110400673322 28695.469974986467 23938.611765294067 22947.661894660203 0.9627494443662842 1.045014918721099 1.1195076775625394 1.1938878797151302 0.9890735771069976 1.1429666426385736 1.0330076549624156 1.250474671742647 1.0431830430125193 1.0 14.48605954648627 -4.912355173404892 2.8101082362159624 1.1040847559357216 0.955545808176225 0.20433348416647112 0.0801413550885376 0.47045945188567223 6.245732346734711 0.01964354773880944 0.14152310223638692 1.2236150967492011e-05 4.912355173404892 -0.1485389477594966 KQLVIYEEIS(ph)DPEEDDE ddPTM_PC-9_Lapatinib_30min_R1 4 KQLVIYEEISDPEEDDE 17 1 Q16385;Q99909;Q7RTT5;Q7RTT3;Q16384 Q16385 SSX2;SSX3;SSX7;SSX9;SSX1 Protein SSX2;Protein SSX3;Protein SSX7;Protein SSX9;Protein SSX1 1 KQLVIYEEIS(1)DPEEDDE;KQLVIYEEIS(1)DPEEDDE;KQLVIYEEIS(1)DPEEDDE;KQLVIYEEIS(1)DPEEDDE 100.68 0.0034888000000000007 3552900.0 69944.8 59869.4 65813.9 52986.8 55483.0 59449.8 53107.1 49941.7 73145.7 53842.4 True False 68947.37432569456 59730.77608266499 60402.93519100083 56883.62603078319 52219.599023774936 56907.27063825249 55856.725782964 52262.173703139466 64907.261007631896 63148.98709951166 1.091820747924993 0.9458706912992892 0.9565147117216064 0.9007844566238986 0.8269269456608396 0.9011588823836031 0.8845229092106206 0.8276011398375005 1.0278432638254278 1.0 15.946471973131066 -3.9145604919396098 1.0599454385528624 0.9005839052526463 1.9303489188899665 0.4066131962320201 0.06261860246261634 8.427745390584207 1.9813919005695932 0.018760992884833468 15.172646182738742 0.00012174174095956851 3.9145604919396098 1.0297650136373202 KQNS(ph)PVAPTAQPK ddPTM_PC-9_AZD4547_30min_R2 2 KQNSPVAPTAQPK 13 1 Q6P1N0;Q6P1N0-2 Q6P1N0 CC2D1A Coiled-coil and C2 domain-containing protein 1A 1 KQNS(1)PVAPTAQPK;KQNS(1)PVAPTAQPK 100.77 0.00099477 71099000.0 325200.0 336570.0 419540.0 395890.0 389360.0 466330.0 401350.0 460530.0 380990.0 407410.0 True False 428606.835419795 445359.6705149245 413976.62547743355 304623.67693952774 335304.0848428189 437170.31138116465 437069.37248202664 389365.6704266063 401128.3535934997 393146.69990595186 1.0901956840088596 1.1328078567655864 1.0529825776903752 0.7748346279198057 0.8528726933814528 1.111977568387943 1.1117208222441697 0.9903826498346545 1.0203019730025895 1.0 18.584708218817177 -5.52814680645343 24.98926892571753 0.980040082259365 1.106850176545603 0.22834496087481615 0.09803351516933233 219.17266874539192 1039651.4628701227 0.029994227151883567 0.052165380084120964 2.9638293440415385e-06 5.52814680645343 0.1268100942862379 KQNS(ph)PVAPTAQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KQNSPVAPTAQPK 13 1 Q6P1N0;Q6P1N0-2 Q6P1N0 CC2D1A Coiled-coil and C2 domain-containing protein 1A 1 KQNS(1)PVAPTAQPK;KQNS(1)PVAPTAQPK 111.78 0.00024227 43000000.0 291590.0 410470.0 329480.0 310390.0 372240.0 256310.0 337510.0 260760.0 261770.0 225980.0 True False 340950.42783498246 451218.7488982758 337336.0527598582 292999.85459795746 299302.24414719816 242868.65239203276 305538.6094392054 253915.3262980583 265597.8910298138 266948.38514330494 1.2772147981039528 1.6902846168410033 1.2636751954081584 1.097589912149749 1.121198931345941 0.9097962973690755 1.144560620867529 0.9511776074680124 0.9949409916348954 1.0 18.02620129613902 -5.629141248709691 2.5743405724227024 1.026777207014716 1.4867334418325888 0.7058596705266659 0.11734576360793218 0.1346082364107628 1.7940713507833757 0.03174294202420402 0.06466551214432463 2.3488687571689616e-06 5.629141248709691 0.45995623481787273 KQNS(ph)PVAPTAQPK ddPTM_PC-9_Lapatinib_30min_R1 2 KQNSPVAPTAQPK 13 1 Q6P1N0;Q6P1N0-2 Q6P1N0 CC2D1A Coiled-coil and C2 domain-containing protein 1A 1 KQNS(0.996)PVAPT(0.004)AQPK;KQNS(1)PVAPTAQPK 108.96 0.00038503 65660000.0 204461.0 277070.0 299140.0 242580.0 329230.0 309890.0 292120.0 299980.0 301720.0 239010.0 True False 201545.3486464444 276428.46143812983 274545.86391379253 260420.14242315726 309865.33869108406 296636.7270888728 307244.5442458624 313918.16593083023 267737.1163475459 280322.5600391941 0.7189765555018646 0.986108507996931 0.9793926820424517 0.9290017271058949 1.1053885161713681 1.0581978384022952 1.0960393063009417 1.1198462438661334 0.9551037073509582 1.0 18.096728329927267 -4.084808232809856 0.903049836583179 1.0509295583814438 3.361060598237739e-23 0.6824165845673928 0.06286975044391827 3.8751998976632587 1.0078902221797865 0.021476611857500577 5.422139033707792 8.226057998067185e-05 4.084808232809856 -1.0509295583814438 KQPPKEPSEVPT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 KQPPKEPSEVPTPK 14 2 P17096-2 P17096-2 HMGA1 High mobility group protein HMG-I/HMG-Y 1 KQPPKEPS(0.002)EVPT(0.998)PK 56.851000000000006 0.032736 27807000.0 118790.0 235230.0 128430.0 184950.0 164060.0 175170.0 141580.0 153290.0 150850.0 177290.0 True False 156562.7490145058 311263.4973266361 126726.9342853286 142312.63494901534 141283.10088173623 164216.5922086051 154180.34572319733 129602.55275377168 158823.62303362144 171083.13106287646 0.9151267459382998 1.8193698899059811 0.7407330781124992 0.8318332384080147 0.8258154968522985 0.9598643138478231 0.9012013327400057 0.7575413890814294 0.9283418069736553 1.0 17.384337990361715 -5.2887079960721 24.99584388285614 0.8611516805934712 1.3672485366939948 0.45791900728538704 0.21709756035563282 492.9008223801302 451817.94935923367 0.05162618383780113 0.10750901964384499 5.1438939219111934e-06 5.2887079960721 0.5060968561005236 KQPPKEPSEVPT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KQPPKEPSEVPTPK 14 2 P17096-2 P17096-2 HMGA1 High mobility group protein HMG-I/HMG-Y 1 KQPPKEPS(0.003)EVPT(0.997)PK 52.019 0.043672 1163000000.0 174570.0 229360.0 129040.0 185520.0 192320.0 172160.0 167820.0 188680.0 158550.0 137660.0 True False 204121.25308533513 252129.3450125665 132116.80298692497 175125.9158639554 154636.27658067163 163131.62652964093 151922.87468841643 183727.3499229847 160868.49380286894 162616.66828403954 1.2552295852526034 1.5504520395915187 0.812443179294259 1.0769247563113653 0.9509251309378157 1.003166700259176 0.9342392529101355 1.1298186825600898 0.9892497214484981 1.0 17.311115616340864 -5.258701634261992 24.999998830943312 0.9923348841221731 1.402840823591021 0.7203563842183002 0.10357217969364763 110.49516348945366 1008984.1102122543 0.02481424163150316 0.05989619921461582 5.511862381948414e-06 5.258701634261992 0.41050593946884795 KQPPKEPSEVPT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 KQPPKEPSEVPTPK 14 2 P17096-2 P17096-2 HMGA1 High mobility group protein HMG-I/HMG-Y 1 KQPPKEPS(0.076)EVPT(0.924)PK 60.489 0.026258 9357700.0 124130.0 89049.0 73904.0 80730.0 70132.0 86217.0 83762.0 70894.0 70615.0 79696.0 True False 122359.88343734595 88842.81251165416 67827.89839768973 86667.15350738514 66006.97364481707 82529.6998916432 88098.78650938625 74187.99405127113 62661.595091084324 93471.347411755 1.3090630104895429 0.9504817783388586 0.7256544414503611 0.9272055652049565 0.7061733405216324 0.882941159798283 0.9425218417072577 0.793697706361952 0.6703829229619511 1.0 16.51223657041058 -4.80198190147166 3.1342356380290246 0.8284115782707672 1.369945221196368 0.6565787677831783 0.10382101635612553 0.19139163760940683 2.8996048095137548 0.02547537270300256 0.2524257122657288 1.577677015497215e-05 4.80198190147166 0.5415336429256009 KQPPVS(ph)PGTALVGSQK ddPTM_PC-9_AZD4547_30min_R2 2 KQPPVSPGTALVGSQK 16 1 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 KQPPVS(0.944)PGT(0.056)ALVGSQK;KQPPVS(0.904)PGT(0.096)ALVGSQK 109.67 0.00096545 246670000.0 220351.0 259640.0 255240.0 210324.0 238017.0 265360.0 242720.0 311340.0 257820.0 229230.0 True False 290418.034414474 343563.5524630692 251855.35082914654 161837.0512734076 204972.44802248082 248766.99725110087 264321.6097890554 263229.55688146205 271447.8388500382 221204.72747218213 1.3128925305224133 1.5531474231547535 1.1385622437062015 0.7316166029668584 0.9266187498106585 1.124600726638561 1.1949184486678546 1.1899816061325579 1.227133985570785 1.0 17.755022692865637 -5.386456830860507 5.5732610996713525 1.05863895991493 1.4286865839144953 0.4916353106743858 0.15054824085939744 0.19573114630654193 7.9823449101531905 0.0440795075026926 0.09379690326901241 4.1071746341515184e-06 5.386456830860507 0.37004762399956537 KQPPVS(ph)PGTALVGSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KQPPVSPGTALVGSQK 16 1 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 KQPPVS(0.9)PGT(0.1)ALVGSQK;KQPPVS(0.839)PGT(0.161)ALVGSQK 116.27 7.4336e-05 665149000.0 526403.0 722887.0 635842.0 550884.0 580797.0 415689.0 573173.0 318282.0 323729.0 329661.0 True False 615512.630966833 794650.4439662497 651002.8847242135 520019.75547002454 466993.99713614944 393889.5370613382 518877.90402683784 309927.4347476543 328462.9241899031 389425.92970495933 1.5805640662735623 2.0405689075925184 1.6716988650895246 1.3353495897512704 1.1991856769526312 1.0114620188741943 1.332417449500487 0.795857212133934 0.8434541696767762 1.0 18.570989422725404 -6.010096888089955 1.124784305960856 0.9859651889313985 1.8549110346976807 0.7845660535385108 0.17429024661275244 0.22944596829294944 0.5911064761787648 0.0700283408432664 0.13883564169992268 9.7701923041948e-07 6.010096888089955 0.8689458457662822 KQPPVS(ph)PGTALVGSQK ddPTM_PC-9_Lapatinib_30min_R1 3 KQPPVSPGTALVGSQK 16 1 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 KQPPVS(0.987)PGT(0.013)ALVGSQK;KQPPVS(0.977)PGT(0.023)ALVGSQK;KQPPVS(0.788)PGT(0.212)ALVGSQK 123.92 5.4655e-05 874414000.0 1078141.0 1845940.0 1506349.0 1232374.0 1552727.0 1524959.0 1549618.0 1600662.0 1223846.0 1308140.0 True False 1062766.5116331538 1841665.8393442126 1382502.799895291 1323006.8950391507 1461398.6506387373 1459740.0584230532 1629849.6377008941 1675034.6000239232 1086003.575810285 1534250.2560130141 0.6926943681240871 1.200368604878102 0.9010934132010104 0.8623149253871973 0.9525164782676374 0.9514354341490631 1.0623101617961008 1.0917610040859689 0.7078399182623784 1.0 20.54910239353525 -6.8039474637310855 3.4677465629683195 0.9761932283109664 0.9320518965548829 0.0136749431804426 0.15134461032540822 1.4435156886763238 35.761686503349225 0.05399967979036394 0.0490433274707351 1.5705527814027125e-07 6.8039474637310855 -0.04414133175608359 KQPPVS(ph)PGTALVGSQKEPSEVPT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 KQPPVSPGTALVGSQKEPSEVPTPK 25 2 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 2 KQPPVS(0.97)PGT(0.036)ALVGS(0.048)QKEPS(0.374)EVPT(0.571)PK 68.938 0.003744 32336000.0 99547.0 90919.0 79808.0 105940.0 115190.0 95117.0 80340.0 92428.0 89579.0 102050.0 True False 131200.87529377046 120306.78873205105 78749.69377437909 81517.16975668403 99197.8568241329 89169.31895362154 87490.10436079731 78145.37638414513 94313.96306084697 98477.26056160254 1.3322961518786118 1.221670749632531 0.7996738874058864 0.8277765779815828 1.007317387368626 0.9054813105594218 0.8884295101412554 0.7935372687917249 0.9577232604053683 1.0 16.58750300906921 -5.14724001095872 4.534113883410589 0.8920925277282958 1.3057868231731558 0.8118026732047738 0.07363642127040479 0.0851092951979268 2.7515407592129835 0.019053524425026558 0.05576192217555737 7.124591838350094e-06 5.14724001095872 0.4136942954448599 KQPPVS(ph)PGTALVGSQKEPSEVPT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KQPPVSPGTALVGSQKEPSEVPTPK 25 2 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 2 KQPPVS(0.683)PGT(0.298)ALVGS(0.136)QKEPS(0.182)EVPT(0.701)PK 54.867 0.042091 13850000.0 64781.0 44296.0 38764.0 61932.0 54393.0 46638.0 54625.0 47097.0 49721.0 39161.0 True False 75747.14381692796 48693.414137934495 39688.28077328865 58462.15082625308 43735.08211341761 44192.221178493244 49450.524549247726 45860.753653396365 50448.07556210947 46260.579301694575 1.6374015405845395 1.0525898048179176 0.857928745648778 1.2637574303811527 0.9454071430492342 0.9552889705571507 1.0689560160228322 0.9913570981095872 1.0905197540460005 1.0 15.497495711897288 -4.763123498460274 5.844855267050145 1.0220988302871523 1.6615420199008815 0.7647681026656783 0.10200023581691066 0.06116481266069558 7.591884154202145 0.024270273023143336 0.15727445906690773 1.7253471926387718e-05 4.763123498460274 0.6394431896137291 KQPPVS(ph)PGTALVGSQKEPSEVPTPK ddPTM_PC-9_AZD4547_30min_R2 3 KQPPVSPGTALVGSQKEPSEVPTPK 25 2 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 KQPPVS(0.5)PGT(0.5)ALVGSQKEPSEVPTPK;KQPPVS(0.801)PGT(0.199)ALVGSQKEPSEVPTPK;KQPPVS(0.677)PGT(0.323)ALVGSQKEPSEVPTPK 92.913 1.0634e-05 75638000.0 204962.0 188513.0 266388.0 328317.0 271765.0 217810.0 182676.0 228112.0 189266.0 247539.0 True False 270135.6525255595 249446.1406773628 262855.5210651731 252628.58809708495 234035.1207553643 204190.30626794646 198933.81010969682 192862.53189228484 199270.21436580303 238872.73495500782 1.130876877080342 1.0442637613051422 1.1003998472855534 1.0575865351257776 0.9797481525023997 0.8548079223290432 0.8328024968909341 0.8073861252043306 0.8342107959844642 1.0 17.86588266774558 -6.522769862857319 2.0430856085263898 0.8492119730640186 1.0852672726153918 0.7782484700238762 0.05445134933652343 0.13509387065467213 1.1346979641999622 0.019045475438068695 0.020594600965818256 3.000752227424315e-07 6.522769862857319 0.23605529955137317 KQPPVS(ph)PGTALVGSQKEPSEVPTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KQPPVSPGTALVGSQKEPSEVPTPK 25 2 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 KQPPVS(0.829)PGT(0.17)ALVGSQKEPSEVPTPK;KQPPVS(0.587)PGT(0.401)ALVGS(0.011)QKEPS(0.001)EVPTPK 77.575 0.00015165 124026000.0 98576.0 82925.0 80469.0 137140.0 139157.0 146038.0 130847.0 145287.0 130372.0 107497.0 True False 115262.96983525237 91157.24596776739 82387.68614038196 129456.49041387918 111890.1847968828 138379.5101947939 118452.22490975562 141473.37019430092 132278.44386040754 126985.35515421603 0.9076871084486275 0.7178563690046181 0.6487967532974735 1.0194600019558326 0.8811266831596363 1.0897281031087431 0.932802249250731 1.1140920149610172 1.041682670413162 1.0 16.954302599271593 -5.775174969656286 24.99837947724165 1.0106010578647993 0.7540877155634774 0.6361833571363977 0.08771338211066014 136.97056002240532 249282.22266262866 0.024715248061324448 0.03687707696275442 1.6781277935539854e-06 5.775174969656286 -0.25651334230132183 KQPPVS(ph)PGTALVGSQKEPSEVPTPK ddPTM_PC-9_Lapatinib_30min_R1 2 KQPPVSPGTALVGSQKEPSEVPTPK 25 2 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 KQPPVS(0.794)PGT(0.204)ALVGS(0.002)QKEPSEVPTPK;KQPPVS(0.5)PGT(0.5)ALVGS(0.001)QKEPSEVPTPK 74.308 0.00052531 48555000.0 409810.0 245853.0 279490.0 251970.0 257460.0 271340.0 264250.0 268858.0 300020.0 246325.0 True False 403966.0342500494 245283.74248366366 256511.41106259936 270500.7143472798 242316.70898583543 259735.42072443382 277931.57201482 281350.1241943834 266228.58824933966 288901.9480425689 1.3982807557619032 0.849020728816691 0.8878839786320967 0.9363063010825468 0.8387506925018405 0.8990435076130484 0.9620273379875844 0.9738602529358065 0.9215188407456207 1.0 18.14022040634861 -4.756605934832302 24.999932988332286 0.9157220800611329 1.3982814899279965 0.8940826861669053 0.049508743488508936 44.97336824309498 232587.6758675035 0.012670674261512894 0.10114157464527192 1.7514351650889823e-05 4.756605934832302 0.48255940986686363 KQPPVSPGT(ph)ALVGS(ph)QKEPSEVPTPK ddPTM_PC-9_Lapatinib_30min_R1 1 KQPPVSPGTALVGSQKEPSEVPTPK 25 2 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 2 KQPPVS(0.039)PGT(0.917)ALVGS(0.64)QKEPS(0.142)EVPT(0.261)PK 69.08800000000001 0.0036696999999999997 29196000.0 70697.0 53775.0 44790.0 51593.0 40076.0 41799.0 30339.0 29149.0 33247.0 28436.0 True False 69688.84781575816 53650.487291426136 41107.53909439988 55387.32132920265 37718.8084724475 40011.35420822804 31909.80497013289 30503.36895365621 29502.372753569103 33351.12471141172 2.089550155168014 1.6086560125232778 1.232568300172922 1.660733237888401 1.1309606137373018 1.1997002966001142 0.9567834742081229 0.9146129018916984 0.8845990355304061 1.0 15.025447794279124 -1.522878745280539 0.29569376980203066 0.8743072467678784 10.570480374236817 0.8295944736717343 0.15503389235119014 21.14885207540832 0.300922321576819 0.1641673134805139 107.93233552047526 0.029999999999986083 1.522878745280539 9.696173127468938 up KQPPVSPGT(ph)ALVGSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KQPPVSPGTALVGSQK 16 1 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 KQPPVS(0.049)PGT(0.95)ALVGS(0.001)QK;KQPPVS(0.019)PGT(0.975)ALVGS(0.005)QK 88.57 0.0033672 696870000.0 274875.0 524990.0 351581.0 356130.0 357010.0 287602.0 341213.0 229057.0 232211.0 228586.0 True False 321405.9084712809 577107.5376619603 359964.0244183679 336177.1906890377 287056.45331772795 272519.64482561464 308890.83447180764 223044.49645595247 235606.6465749478 270026.8323142194 1.1902739654304937 2.1372229297213083 1.3330676115901408 1.2449769817609897 1.0630664029109962 1.009231721492383 1.1439264454739957 0.8260086397503065 0.8725304983794419 1.0 18.042743248095384 -5.82036671856462 1.6909866977326635 0.9826755829869602 1.6657345338438254 0.5445352365722781 0.23768622820055385 0.2546543748159489 1.4846630974761035 0.07311902839455152 0.1462392602432577 1.512283735700436e-06 5.82036671856462 0.6830589508568652 KQPPVSPGTALVGS(ph)QK ddPTM_PC-9_AZD4547_30min_R2 2 KQPPVSPGTALVGSQK 16 1 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 KQPPVSPGTALVGS(1)QK;KQPPVSPGTALVGS(1)QK 158.52 2.25e-05 17041600.0 157444.0 210788.0 157719.0 142183.0 159897.0 199622.0 210341.0 203198.0 189382.0 163747.0 True False 207507.9169613593 278921.09881599684 155627.5430082361 109404.90605545207 137698.0615731254 187139.60478315994 229060.9415154901 171798.41812551973 199392.34588898427 158014.2673707079 1.3132226628278905 1.7651640162444102 0.9848955135369362 0.6923735930679202 0.8714280290277847 1.1843209344136172 1.4496218938135743 1.0872335832970934 1.2618629267267474 1.0 17.269695302052362 -5.2723857145306905 24.94876582534044 1.0671495407872806 1.5391933455356246 0.4216156029192645 0.22147125909590223 635.5081628449893 1448444.4074276013 0.06364454289522536 0.13453241588057857 5.340898018923598e-06 5.2723857145306905 0.47204380474834395 KQPPVSPGTALVGS(ph)QK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KQPPVSPGTALVGSQK 16 1 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 KQPPVSPGT(0.002)ALVGS(0.998)QK 78.794 0.004339 5062500.0 92930.0 110780.0 105220.0 89581.0 94503.0 77634.0 99570.0 75690.0 82329.0 73442.0 True False 108661.21354883575 121777.50628048572 107728.843849072 84562.06699552052 75985.81554546187 73562.73637315373 90138.00877562664 73703.21770018419 83532.90587383427 86756.45323344777 1.252485659556019 1.403670871062489 1.2417386814925557 0.9747063629719567 0.8758520284479145 0.8479223577202741 1.0389775678482343 0.8495416185567268 0.9628437166404273 1.0 16.404683453685628 -5.730239054020482 3.195658653295576 0.9228221445965589 1.3280816888458387 0.8597238011177402 0.06801774143203394 0.07532404451049192 1.577376421030441 0.018589576887640392 0.032992355686448926 1.8610624473201252e-06 5.730239054020482 0.4052595442492798 KQPPVSPGTALVGS(ph)QK ddPTM_PC-9_Lapatinib_30min_R1 2 KQPPVSPGTALVGSQK 16 1 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 KQPPVSPGTALVGS(1)QK;KQPPVSPGTALVGS(1)QK 104.82 0.00055049 16216600.0 152818.0 182111.0 124112.0 136993.0 146378.0 139628.0 135872.0 143679.0 133398.0 121383.0 True False 150638.7872966113 181689.33316836692 113907.99044617468 147067.92221525122 137768.33383022068 133656.4359287655 142906.78733319795 150354.85086597706 118373.312496785 142363.8898173195 1.058124974597913 1.2762318689206202 0.8001185595050876 1.0330423143394574 0.967719651429897 0.9388366396863184 1.0038134495803333 1.0561305332336137 0.8314841119379426 1.0 17.119223731781034 -5.2526348393407405 24.999976203906012 0.9604635116497179 1.167178415062211 0.46153470354832904 0.0919315599333182 535.6649953437473 1520981.4573482787 0.021948775412881597 0.05621934727732247 5.589399614760706e-06 5.2526348393407405 0.2067149034124932 KQPPVSPGTALVGS(ph)QKEPSEVPT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 KQPPVSPGTALVGSQKEPSEVPTPK 25 2 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 2 KQPPVS(0.02)PGT(0.101)ALVGS(0.669)QKEPS(0.338)EVPT(0.872)PK 52.92 0.014509000000000001 133420000.0 41497.0 30539.0 27740.0 33064.0 33254.0 25794.0 26256.0 21498.0 29969.0 19376.0 True False 40905.24517038223 30468.28882181055 25459.3242794966 35495.636858270635 31298.06509987948 24690.850748750807 27615.407208405348 22496.875562307487 26593.575632439366 22725.115783102887 1.8000016176285913 1.3407319510541307 1.1203165925529284 1.561956260071651 1.3772455726342638 1.0865005478700147 1.2151932457452475 0.9899564770990031 1.1702283889885765 1.0 14.472000024432322 -1.5228787452803376 0.22943343887865544 1.0069039110757863 4.534228041545958 0.5819766673416642 0.15874822845026657 40.32592210502273 0.5271636798128827 0.24343092634890523 53.37382622819275 0.029999999999999995 1.5228787452803376 3.527324130470172 KQPPVSPGTALVGS(ph)QKEPSEVPTPK ddPTM_PC-9_Lapatinib_30min_R1 1 KQPPVSPGTALVGSQKEPSEVPTPK 25 2 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 KQPPVS(0.001)PGT(0.003)ALVGS(0.904)QKEPS(0.087)EVPT(0.005)PK 57.82899999999999 0.013396000000000002 13689000.0 74699.0 62316.0 56796.0 64306.0 51581.0 48624.0 57776.0 55176.0 54418.0 45699.0 True False 73633.77856188099 62171.711130683594 52126.45211890011 69035.27775852734 48547.10699214782 46544.46486808015 60767.35857986086 57739.67838989106 48288.87179305569 53598.01125991015 1.3738154985790871 1.1599630223068806 0.9725445197234263 1.2880193898194847 0.9057632149209934 0.868399102391587 1.1337614428487794 1.0772727762210603 0.9009452152784342 1.0 15.709891850406116 -1.522878908305831 0.6899958755414142 1.0058770936373178 43.716064495873816 0.4711681220042955 0.11784448143998415 251.87887301713423 1.3919157107612892 0.0477891046877735 16566.956721621023 0.02999998873859999 1.522878908305831 42.7101874022365 KQPPVSPGTALVGSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KQPPVSPGTALVGSQK 16 1 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 0 84.41 0.0031505 5795600.0 39375.0 49290.0 39048.0 37521.0 42280.0 32995.0 40317.0 38493.0 35760.0 28445.0 False True 46040.409808300916 54183.185453738326 39979.05241036464 35418.820014723264 33995.53750951954 31264.684115622156 36497.88189019717 37482.599536704794 36282.92234872659 33601.85332950391 1.3701747149725043 1.612505861578864 1.1897871232971924 1.0540734068267592 1.0117161448255583 0.9304452289889137 1.086186572279048 1.1154920286433552 1.0797893197417354 1.0 15.036253187420922 -5.456925837050434 3.6967325086840472 1.0431918466789685 1.4885532193929047 0.8501290824240528 0.07476197051155561 0.07992197730748923 2.1181522103433443 0.020606528139266122 0.044996713557027626 3.4919994203997506e-06 5.456925837050434 0.4453613727139363 KQPPVSPGTALVGSQK ddPTM_PC-9_Lapatinib_30min_R1 2 KQPPVSPGTALVGSQK 16 1 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 0 ; 193.54 6.5897e-12 13637400.0 84049.0 91484.0 92027.0 90762.0 89504.0 81504.0 96668.0 93188.0 80523.0 79537.0 False True 82850.44584730115 91272.17441876022 84460.89529449282 97436.94025315606 84239.55069163446 78018.26391510379 101672.99603984326 97517.85467951966 71453.65179521893 93284.86447360947 0.8881445700201425 0.978424259217114 0.9054083507661312 1.0445096404757197 0.90303556924249 0.8363442918135487 1.0899195342520631 1.0453770312021808 0.7659726172988476 1.0 16.50935540146017 -7.249707459363499 24.987373911418885 0.9790987234998014 0.9317717309896569 0.05844918850332892 0.09484223120383672 2614.9317269913417 5569455.156329059 0.03653080219285026 0.02805200061993618 5.6272024574924986e-08 7.249707459363499 -0.047326992510144494 KQPPVSPGTALVGSQKEPS(ph)EVPT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 KQPPVSPGTALVGSQKEPSEVPTPK 25 2 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 2 KQPPVS(0.003)PGT(0.01)ALVGS(0.471)QKEPS(0.539)EVPT(0.978)PK 47.273999999999994 0.043927999999999995 170000000.0 63752.0 50558.0 51197.0 74931.0 66056.0 58041.0 43649.0 41839.0 46246.0 62538.0 True False 84023.80987602322 66899.8847844239 50518.09432847448 57656.81562240967 56885.264609557315 54411.68709470589 47533.67644068264 35373.74391457405 48690.46914691981 60348.56365508573 1.3923083630664392 1.1085580290987767 0.8371051648752403 0.9553966512266904 0.9426117402673833 0.9016235648239903 0.7876521587548481 0.5861571804218577 0.8068206796967659 1.0 15.881031813622625 -1.5228787453455659 0.5920235135691201 0.8053006665800168 36.017001485927615 0.7014573141254299 0.11122523843048568 92.48306207049728 0.7367751057063061 0.05405242479234281 4202.231931772435 0.029999999995494186 1.5228787453455659 35.2117008193476 KQPPVSPGTALVGSQKEPS(ph)EVPT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KQPPVSPGTALVGSQKEPSEVPTPK 25 2 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 2 KQPPVS(0.005)PGT(0.012)ALVGS(0.018)QKEPS(0.97)EVPT(0.995)PK 49.433 0.032676 80333000.0 82604.0 64517.0 51295.0 78384.0 72658.0 67385.0 74940.0 69777.0 56212.0 56334.0 True False 96587.2256966321 70921.82138200112 52518.06733737077 73992.39860435665 58421.18647981723 63851.211975487204 67841.14068138445 67945.42768484277 57033.99415734394 66546.90826030135 1.4514156738706272 1.065741793812375 0.7891886897576652 1.111883339717781 0.8778948264778886 0.9594917877436198 1.0194484229984155 1.021015543187537 0.857049495586674 1.0 16.02208402027498 -4.796346110634201 3.643641711969187 0.9588262824764252 1.4978947786531343 0.73594742277153 0.08908002694282376 0.12102918812292472 2.7565179373140407 0.021086794423797666 0.17372178434705857 1.5982837699716015e-05 4.796346110634201 0.539068496176709 KQPPVSPGTALVGSQKEPS(ph)EVPTPK ddPTM_PC-9_AZD4547_30min_R2 1 KQPPVSPGTALVGSQKEPSEVPTPK 25 2 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 KQPPVSPGTALVGS(0.035)QKEPS(0.948)EVPT(0.016)PK 78.057 0.00036026 18036000.0 78391.0 82681.0 81340.0 98023.0 115400.0 110810.0 78528.0 83767.0 81752.0 108850.0 True False 103317.70736590741 109406.0163349214 80261.3784533882 75425.31179025318 99378.7019489967 103881.03318282527 85516.83987110626 70822.73492416451 86073.24381998413 105039.19463136126 0.9836110009078471 1.0415732595712073 0.7641088522724143 0.7180682606617554 0.9461106618131427 0.9889740067733707 0.8141421892202297 0.6742505516414077 0.8194392971315251 1.0 16.680568234224694 -7.493102518502481 23.451382449703406 0.7969462565507002 0.9000131701443326 0.07503914872534523 0.12059510551669686 683.4270564907357 538260.587951944 0.053253211377066415 0.03582201564521154 3.212902019255508e-08 7.493102518502481 0.1030669135936324 KQPPVSPGTALVGSQKEPS(ph)EVPTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KQPPVSPGTALVGSQKEPSEVPTPK 25 2 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 KQPPVSPGT(0.004)ALVGS(0.038)QKEPS(0.937)EVPT(0.022)PK 70.453 0.0001493 115660000.0 65034.0 59503.0 44260.0 83367.0 81424.0 82300.0 88423.0 84376.0 73462.0 69055.0 True False 76042.97171995028 65410.06459837269 45315.326256984736 78696.21726946053 65469.55170707467 77984.04311913019 80046.93331291774 82161.21940376163 74536.2427735503 81574.12486092091 0.9321947596691852 0.8018481927926656 0.5555110316444669 0.9647203375290013 0.8025774327177448 0.9559899447537855 0.9812784807608179 1.0071970682350766 0.9137240871493284 1.0 16.315823984507325 -6.623285215052856 1.4191059008104872 0.97940730842186 0.7868850745238875 0.3567715987630976 0.10570841558381633 0.4480820369459802 1.874817070395611 0.04632630637942831 0.04720510999829231 2.3807554377290452e-07 6.623285215052856 -0.19252223389797252 KQPPVSPGTALVGSQKEPSEVPT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KQPPVSPGTALVGSQKEPSEVPTPK 25 2 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 KQPPVSPGTALVGSQKEPS(0.04)EVPT(0.959)PK;KQPPVSPGTALVGSQKEPS(0.073)EVPT(0.927)PK;KQPPVSPGTALVGS(0.005)QKEPS(0.095)EVPT(0.901)PK 96.46700000000001 1.9932e-05 350994000.0 902544.0 517588.0 645953.0 1175105.0 1139374.0 1225174.0 1143392.0 1360872.0 1160243.0 865651.0 True False 1055326.8731434427 568970.7160200763 661354.9693103937 1109267.6765918098 916121.8437646931 1160923.7186444392 1035081.6323187795 1325150.551963074 1177209.3589108917 1022586.6738104552 1.0320170408743818 0.5564034136098469 0.6467471034469799 1.0847664114948379 0.8958867421486697 1.1352814860362888 1.0122189725607946 1.2958809124953463 1.151207412594443 1.0 19.963791699608116 -6.182819108529825 1.2213518773142502 1.1314270994660676 0.7370989416190685 0.44524827014531265 0.16076321332456145 0.39425143729773426 1.2017215827094436 0.06353038392104092 0.09991396918026171 6.564186195430106e-07 6.182819108529825 -0.39432815784699904 KQPPVSPGTALVGSQKEPSEVPT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 KQPPVSPGTALVGSQKEPSEVPTPK 25 2 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 KQPPVSPGTALVGS(0.003)QKEPS(0.367)EVPT(0.63)PK;KQPPVSPGT(0.002)ALVGS(0.032)QKEPS(0.264)EVPT(0.702)PK 66.89399999999999 0.0061547 474842000.0 656450.0 376461.0 404152.0 448447.0 405919.0 399668.0 312116.0 320025.0 407499.0 329851.0 True False 647088.9026218122 375589.3276841956 370924.18263183447 481427.2883553375 382043.6424874591 382575.1313116127 328275.83928468346 334894.52980870026 361602.1714652946 386865.30585117015 1.672646507285282 0.9708529609752277 0.9587941255567943 1.2444312815699892 0.9875365836874347 0.9889104179809604 0.8485533189966988 0.8656618330554992 0.9346978547732723 1.0 18.561471827873454 -4.761087849138984 24.999998832365893 0.9778812892663928 1.6726472848325096 0.8078939577297093 0.10166143272052147 3.855541727410114 273817.35326042044 0.02778593310429222 0.15814680349998528 1.733453319145983e-05 4.761087849138984 0.6947659955661167 KQQQEPT(ph)GEPSPK ddPTM_PC-9_AZD4547_30min_R2 1 KQQQEPTGEPSPK 13 1 F5H2U8;F5H2A4;F5H6H0;P52926-3;P52926-6;P52926-4;P52926-5;P52926-2;P52926 F5H2U8 HMGA2 High mobility group protein HMGI-C 1 KQQQEPT(0.935)GEPS(0.065)PK 154.13 0.00054655 36013000.0 36506.0 33303.0 35354.0 34651.0 37091.0 37686.0 37438.0 32010.0 31908.0 28101.0 True False 48114.1486280289 44067.543474339815 34885.182860106754 26662.747302613334 31941.554887263726 35329.48846248491 40769.909472983956 27063.59001662359 33594.59173852694 27117.192543278714 1.774304200231617 1.6250776478430997 1.2864599756936645 0.9832414347488189 1.177907883947993 1.3028446217689928 1.5034708850451857 0.9980233010268459 1.2388668806665872 1.0 14.726920202804418 -5.232366509521033 2.910081196389603 1.1881156796930077 1.7453009107856525 0.6534104619301686 0.15252194231784547 0.16930468076005056 2.824900272014056 0.042266230319639796 0.1341779039744477 5.856437198346755e-06 5.232366509521033 0.5571852310926448 KQQQEPT(ph)GEPSPK ddPTM_PC-9_Lapatinib_30min_R1 2 KQQQEPTGEPSPK 13 1 F5H2U8;F5H2A4;F5H6H0;P52926-3;P52926-6;P52926-4;P52926-5;P52926-2;P52926 F5H2U8 HMGA2 High mobility group protein HMGI-C 1 KQQQEPT(0.503)GEPS(0.497)PK;KQQQEPT(0.898)GEPS(0.102)PK 130.27 0.00028158 122716000.0 80425.0 75289.0 57919.0 75035.0 82996.0 72263.0 67248.0 60544.0 62508.0 60234.0 True False 79278.12475186138 75114.67294624221 53157.12339380547 80553.32420942203 78114.33845641419 69172.47994328062 70729.77239300887 63357.09526673849 55467.69080157898 70645.36664324006 1.1221985038624946 1.0632639692504138 0.7524502443627984 1.1402492199696164 1.105724864461282 0.9791509794634156 1.0011947811127524 0.8968329881659837 0.7851568112271463 1.0 16.10830732241551 -7.743516695863087 3.4185114512752284 0.8763283880532184 1.0226781121037258 0.21155937965121308 0.11438112284295514 0.36556837886426957 8.873825510509759 0.06640390414351557 0.03225125970992316 1.8050253440433463e-08 7.743516695863087 0.1463497240505074 KQQQEPTGEPS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 5 KQQQEPTGEPSPK 13 1 F5H2U8;F5H2A4;F5H6H0;P52926-3;P52926-6;P52926-4;P52926-5;P52926-2;P52926 F5H2U8 HMGA2 High mobility group protein HMGI-C 1 KQQQEPT(0.099)GEPS(0.901)PK;KQQQEPT(0.002)GEPS(0.998)PK;KQQQEPT(0.081)GEPS(0.919)PK;KQQQEPTGEPS(1)PK;KQQQEPTGEPS(1)PK 143.93 5.4388e-06 25963800.0 212068.8 183169.2 174642.9 214485.0 189162.7 205666.8 189064.1 168349.3 198419.4 204276.9 True False 279502.2670949358 242375.06183106755 172327.02103635616 165038.79701021675 162900.72429087915 192806.42248357993 205890.43863430677 142334.7839670592 208907.44440276644 197125.22790804922 1.4178919160226011 1.2295486701688203 0.8742007446999103 0.8372281861720943 0.8263819198568821 0.9780910567850614 1.044465190068651 0.7220526031982699 1.0597702111482816 1.0 17.588752897438 -5.090329705136513 3.0556758672035818 0.9081086384620862 1.4003791739702631 0.725254083505847 0.10258901476548521 0.1281709516699339 2.2046022371234906 0.026517218047709366 0.10417003742820388 8.122136704384723e-06 5.090329705136513 0.4922705355081769 KQQQEPTGEPS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 KQQQEPTGEPSPK 13 1 F5H2U8;F5H2A4;F5H6H0;P52926-3;P52926-6;P52926-4;P52926-5;P52926-2;P52926 F5H2U8 HMGA2 High mobility group protein HMGI-C 1 KQQQEPTGEPS(1)PK;KQQQEPT(0.101)GEPS(0.899)PK;KQQQEPTGEPS(1)PK;KQQQEPTGEPS(1)PK;KQQQEPT(0.001)GEPS(0.999)PK;KQQQEPTGEPS(1)PK;KQQQEPT(0.13)GEPS(0.87)PK 193.77 2.0434e-06 190600200.0 432647.3 382784.6 294019.4 460105.0 419840.3 370992.2 487146.8 487498.5 373417.8 331334.1 True False 505885.94271631405 420784.9253527089 301029.93757078383 434326.80853053596 337575.60706381133 351536.71593755734 441000.72846659063 474702.1809223575 378878.32888792816 391402.3494907066 1.2924959274633219 1.0750700037959275 0.7691061077238921 1.1096683734670545 0.8624772117568157 0.8981466677320091 1.1267196761604052 1.212824045486801 0.9680021833822032 1.0 18.57829289056611 -9.766944529360842 12.871016393755596 1.0000073533230953 1.0293394905035687 0.003425189118530181 0.15410485316845343 0.0 0.0 0.15323847009539052 0.03716578812419696 1.7102337422277912e-10 9.766944529360842 0.02933213718047334 KQQQEPTGEPS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 5 KQQQEPTGEPSPK 13 1 F5H2U8;F5H2A4;F5H6H0;P52926-3;P52926-6;P52926-4;P52926-5;P52926-2;P52926 F5H2U8 HMGA2 High mobility group protein HMGI-C 1 KQQQEPTGEPS(1)PK;KQQQEPTGEPS(1)PK;KQQQEPT(0.005)GEPS(0.995)PK;KQQQEPTGEPS(1)PK;KQQQEPT(0.014)GEPS(0.986)PK 142.57 0.00012063 1170134600.0 727920.0 655313.0 509253.0 640360.0 641750.0 534520.0 638520.0 525916.0 557388.0 574990.0 True False 717539.7273158196 653795.6630108091 467384.1841134282 687454.2105783375 604003.5267290443 511659.82562697784 671579.4412976454 550351.9773107496 494609.09388415085 674376.255373984 1.0640050292368297 0.9694820329168297 0.6930614480995246 1.0193926685587424 0.8956476772659892 0.7587156599148502 0.9958527393957731 0.8160903841514183 0.7334319527751745 1.0 19.3631942146651 -5.008280412583965 21.407558570885726 0.8628273335039874 1.0403751258442888 0.25368759529975093 0.11011246706095273 73.4746054076892 189988.70935733226 0.026590867530085802 0.0861362387354518 9.811142586586193e-06 5.008280412583965 0.17754779234030138 KQS(ph)AGPNSPTGGGGGGGSGGTR ddPTM_PC-9_AZD4547_30min_R2 2 KQSAGPNSPTGGGGGGGSGGTR 22 1 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 KQS(1)AGPNSPTGGGGGGGSGGTR;KQS(1)AGPNSPTGGGGGGGSGGTR 102.06 3.2705e-05 6404100.0 4472.6 4060.14 8051.3 7814.6 7203.1 5677.9 6149.5 5971.6 5162.5 5900.3 True False 5894.793764140751 5372.500854634896 7944.534501374032 6013.064704366456 6203.073899556477 5322.860015420661 6696.793586839965 5048.826433716637 5435.379210547364 5693.732292911548 1.0353127721651956 0.9435815697417719 1.3953122649030472 1.0560849009098061 1.0894565428162186 0.9348630637319202 1.1761693810538274 0.886734074238476 0.9546250035875725 1.0 12.475158946908337 -7.265099899563282 0.9419824498164934 0.9565033533377815 1.1080958047157992 0.1461908854102958 0.13058591857831403 1.1135084123381471 1.9194865254269926 0.10046099381603357 0.05762766136030877 5.4312538348649464e-08 7.265099899563282 0.1515924513780177 KQS(ph)AGPNSPTGGGGGGGSGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KQSAGPNSPTGGGGGGGSGGTR 22 1 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 KQS(0.936)AGPNS(0.062)PT(0.002)GGGGGGGSGGTR;KQS(0.998)AGPNS(0.002)PTGGGGGGGSGGTR 65.223 0.0013816 3827600.0 6013.3 5122.5 7143.0 4675.1 5135.799999999999 4057.69 3629.8999999999996 3750.6 3047.6 3647.9500000000003 True False 7031.232921911256 5631.027946576884 7313.316209978352 4413.169303878705 4129.476857648778 3844.897593245003 3286.049593799803 3652.1507240891847 3092.165384507247 4309.294457843691 1.6316436462384574 1.306716911936106 1.6971029205643633 1.0241048382864493 0.9582721482706728 0.8922336662899881 0.7625493281895838 0.8475054930260367 0.7175572276985969 1.0 12.073235967087314 -5.8998852530188195 4.392389553723949 0.8616198620893363 1.5189369379586362 0.8569185462688717 0.12443449171276 0.07494314686153294 2.5652707976221154 0.035474395067709864 0.054090338520714785 1.259258082325763e-06 5.8998852530188195 0.6573170758692999 KQS(ph)AGPNSPTGGGGGGGSGGTR ddPTM_PC-9_Lapatinib_30min_R1 2 KQSAGPNSPTGGGGGGGSGGTR 22 1 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 KQS(0.991)AGPNS(0.008)PT(0.001)GGGGGGGSGGTR;KQS(0.985)AGPNS(0.015)PTGGGGGGGSGGTR 52.96 0.0098911 4628300.0 8669.0 8373.9 7938.0 8419.74 8132.700000000001 8255.1 6328.7 4491.77 7207.200000000001 6947.8 True False 8545.378470300098 8354.510749040881 7285.36828156612 9038.955767029263 7654.350575503395 7902.0486165779885 6656.369119433076 4700.474032212574 6395.449240819415 8148.717972638427 1.0486776569018057 1.0252546200633597 0.8940508563468212 1.109248816486232 0.9393318803282912 0.9697290596031548 0.8168609027559519 0.5768360186222807 0.7848411568904339 1.0 12.992357384496012 -7.296118109325522 3.28615023401868 0.751256938992805 0.9996634224682482 0.43420494021066125 0.11154678750664661 0.2019835220510782 4.4870712000238475 0.04766851456442806 0.03194628177934604 5.056871182645142e-08 7.296118109325522 0.24840648347544325 KQS(ph)ESEDTLPSFSS ddPTM_PC-9_AZD4547_30min_R2 1 KQSESEDTLPSFSS 14 1 Q9HB20 Q9HB20 PLEKHA3 Pleckstrin homology domain-containing family A member 3 1 KQS(0.999)ES(0.001)EDTLPSFSS 129.77 3.1641e-05 3919600.0 27680.0 22981.0 30064.0 39717.0 36825.0 28783.0 29026.0 27197.0 25583.0 34220.0 True False 36481.664220233404 30409.158832051264 29665.331716531346 30560.859271533107 31712.48439576948 26983.19445989767 31609.257769187236 22994.328574886353 26935.265151270374 33021.96821575735 1.1047695274209963 0.9208766307739552 0.8983514102704426 0.9254705555966874 0.960345070547218 0.8171285940194774 0.9572190719420535 0.6963342834275388 0.8156771569544866 1.0 15.01113849163854 -1.522878745280543 0.601200432743536 0.8598257692110728 14.905250146304642 0.36280526174367866 0.08540332684499652 188.11956814844015 1.4514760070501989 0.038773546833094336 3472.1105941845562 0.02999999999998581 1.522878745280543 14.04542437709357 KQS(ph)ESEDTLPSFSS ddPTM_PC-9_Lapatinib_30min_R1 1 KQSESEDTLPSFSS 14 1 Q9HB20 Q9HB20 PLEKHA3 Pleckstrin homology domain-containing family A member 3 1 KQS(0.825)ES(0.175)EDTLPSFSS 90.229 0.0073647999999999995 3545000.0 23577.0 19331.0 19365.0 16732.0 24565.0 32808.0 26639.0 28135.0 32189.0 27732.0 True False 23240.787656507728 19286.240257193087 17772.884451061702 17962.52709631575 23120.134996648198 31404.878319183397 28018.237074371933 29442.254811867224 28563.535854803 32525.43924943277 0.7145418537864339 0.5929586410590729 0.5464302669293437 0.552260861369582 0.7108323678380886 0.9655481691836363 0.8614253249434767 0.9052069854023781 0.8781906259821268 1.0 14.989280919926781 -6.591976118399676 3.9304049106684107 0.9115697501450182 0.5991829863547645 0.8724957060565767 0.058097561041887194 0.07647138633005786 2.359710889691505 0.020041166070688232 0.020286120132763204 2.5587265859201074e-07 6.591976118399676 -0.31238676379025365 KQS(ph)LGELIGTLNAAK ddPTM_PC-9_AZD4547_30min_R2 16 KQSLGELIGTLNAAK 15 1 P60174;P60174-3 P60174 TPI1 Triosephosphate isomerase 1 KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(0.918)LGELIGT(0.082)LNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK 167.93 0.0002299 12978240200.0 1857141.3000000003 1700567.5 2205770.9 2676446.7 2569892.0 2253970.6 2099607.0 2300735.2 1918240.0999999999 2303104.0 True False 2447673.602461266 2250242.68796503 2176520.936640898 2059433.264004307 2213106.8553649117 2113029.4620676185 2286467.9555222895 1945209.4404753011 2019634.355521218 2222473.0299702985 1.1013288212968673 1.0124949358756008 0.9793238915794562 0.926640384937238 0.9957856970684985 0.9507559522987136 1.0287944666544935 0.8752454649590493 0.9087328972213483 1.0 21.083734481173735 -4.5266679869551325 1.1795714895741238 0.9536426702136723 1.2479593135010318 0.513241422845645 0.04330033232269543 2.141320216892609 1.7102000157178487 0.013431520535365815 0.894855783422848 2.9739387042195776e-05 4.5266679869551325 0.2943166432873595 KQS(ph)LGELIGTLNAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 17 KQSLGELIGTLNAAK 15 1 P60174;P60174-3 P60174 TPI1 Triosephosphate isomerase 1 KQS(0.848)LGELIGT(0.152)LNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK 143.33 9.0931e-06 18786457300.0 6025276.8 6590450.899999999 6603374.0 7270852.5 7744136.7 7337720.3 7481803.4 7131952.999999999 6682266.0 5485206.7 True False 7045237.157598658 7244707.310579359 6760823.479595347 6863490.206846839 6226728.70538545 6952917.330149667 6773072.818386191 6944746.790678844 6779981.498644747 6479631.2538376525 1.0872898289429693 1.1180740117408037 1.0433963314796895 1.059240863865801 0.9609696079074844 1.0730421312218508 1.0452867691158727 1.0717811737459164 1.0463529841500174 1.0 22.627480283144443 -5.2741251208334425 21.442349727052335 1.0396617654619158 1.102681894741027 0.3836423132439738 0.03295292248242681 105.24178684161123 177889.93942520954 0.008593779374365344 0.01817221310124204 5.319549802314986e-06 5.2741251208334425 0.06302012927911127 KQS(ph)LGELIGTLNAAK ddPTM_PC-9_Lapatinib_30min_R1 21 KQSLGELIGTLNAAK 15 1 P60174;P60174-3 P60174 TPI1 Triosephosphate isomerase 1 KQS(0.901)LGELIGT(0.099)LNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(0.999)LGELIGT(0.001)LNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(0.999)LGELIGT(0.001)LNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK 166.21 3.4488e-06 12375704600.0 1389540.7999999998 1358377.5000000002 1289639.4 1190360.0999999999 1252477.3 1192810.9000000001 1020679.9 1092610.4999999998 1272331.5 1099450.0 True False 1369725.6933814269 1355232.2603572118 1183610.2266840476 1277903.1526788843 1178809.0476791137 1141797.1583850153 1073525.7109968942 1143377.172600732 1129028.1282253356 1289488.4675749599 1.0622240739828894 1.050984397639392 0.9178912851465596 0.9910155730839043 0.9141679645231785 0.8854651957704623 0.8325205986648256 0.8866904988696735 0.8755627961129505 1.0 20.29836743989464 -5.2112233603712985 0.756956249652051 0.8874103981499144 1.123169144067329 0.5827932307493761 0.048382284853931104 1.096152300998156 0.7160987625368697 0.020455618542565262 0.19794641181180916 6.148605647389729e-06 5.2112233603712985 0.23575874591741464 KQS(ph)LPATSIPTPASFK ddPTM_PC-9_AZD4547_30min_R2 2 KQSLPATSIPTPASFK 16 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 KQS(1)LPATSIPTPASFK;KQS(0.993)LPAT(0.005)S(0.002)IPTPASFK 111.93 0.00018525 97007000.0 228847.0 150304.0 201260.0 223168.0 199799.0 150031.0 156130.0 170609.0 176639.0 184646.0 True False 301615.5856866958 198886.82864508202 198591.16089905228 171720.06551122933 172060.35763178134 140649.53785265275 170025.26753611246 144245.29925479955 185975.77692433447 178181.5997418679 1.6927426071134564 1.11620295773082 1.1145435958973977 0.9637362430239744 0.9656460480826617 0.7893606189214378 0.9542246100743762 0.809540937244744 1.0437428847521744 1.0 17.442988836370887 -1.6326790599431569 0.8363924405022775 0.917300135059892 199.99999999999997 0.871831073963987 0.08573025587995939 151.8688727244362 0.5528295087000069 0.028277557924888504 57320.20426621152 0.02329812333844523 1.6326790599431569 199.08269986494008 KQS(ph)LPATSIPTPASFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KQSLPATSIPTPASFK 16 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 KQS(0.999)LPATSIPTPASFK;KQS(1)LPATSIPTPASFK 104.35 0.00057456 70863000.0 150192.0 151277.0 135227.0 142185.0 126391.0 112712.0 98570.0 120783.0 111895.0 79177.0 True False 175616.53917278294 166294.78080513593 138451.3245312537 134218.83541998966 101625.59085538518 106801.18430186412 89232.73601499962 117612.57423016688 113531.2526904575 93531.16333521297 1.877625947443617 1.7779612150138695 1.4802694588011074 1.4350172780269315 1.0865425728873062 1.1418780702971882 0.9540428327101214 1.2574693827836485 1.2138334287959702 1.0 16.51315951137792 -5.5732053026393045 1.0375024925282634 1.107169501756617 1.928422568604948 0.8925591195786797 0.0981850319360663 0.21745148648860513 0.403581022386959 0.03716156962276998 0.14901578995718304 2.6717431055280265e-06 5.5732053026393045 0.8212530668483311 KQS(ph)LPATSIPTPASFK ddPTM_PC-9_Lapatinib_30min_R1 2 KQSLPATSIPTPASFK 16 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 KQS(1)LPATSIPTPASFK;KQS(1)LPATSIPTPASFK 148.38 3.7851999999999998e-06 86101000.0 303090.0 212202.0 263840.0 218260.0 213768.0 186854.0 168911.0 169091.0 225910.0 220258.0 True False 298767.88102010085 211710.65930665165 242148.0936518524 234311.56849401572 201194.58652405834 178862.68999794836 177656.38509212947 176947.58515704394 200465.6368622372 258329.3018246636 1.1565388785159347 0.8195379223776422 0.9373620876202657 0.9070266781158667 0.7788299085816273 0.6923825084285182 0.6877128681774961 0.684969083674232 0.7760081239189028 1.0 17.978851769458856 -1.5228787452803398 0.5472761060108445 0.7550898581833533 16.5196347994244 0.4788187194141853 0.10631690511165316 110.73916101009267 1.0230121309500249 0.05285134926636295 2049.913941305125 0.029999999999999843 1.5228787452803398 15.764544941241045 KQS(ph)LYLK ddPTM_PC-9_AZD4547_30min_R2 1 KQSLYLK 7 1 A0A494BZT8;Q9Y6A5;H0Y8F2;A0A494C117 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 KQS(1)LYLK 58.433 0.038118 16405000.0 64905.0 60312.0 100000.0 119110.0 139290.0 124180.0 125430.0 174120.0 128350.0 141960.0 True False 85543.43989213332 79806.67453455788 98673.93466116076 91651.02973115571 119951.98782041337 116415.00496925604 136593.02700989295 147213.75487955322 135134.3189682817 136990.02360926126 0.6244501434362124 0.582572894229084 0.720300150780395 0.6690343378038487 0.8756257182826266 0.8498064450394457 0.9971020035699777 1.0746312103679407 0.9864537242049639 1.0 17.063711306210074 -6.510613350252755 0.8232613354415184 1.0347312605953156 0.6027153777059374 0.9211941483933027 0.04734126755699418 0.15211496815627137 0.22804491038325744 0.027320002214618715 0.0342535909325937 3.085934116076355e-07 6.510613350252755 -0.4320158828893782 KQS(ph)LYLK ddPTM_PC-9_Lapatinib_30min_R1 1 KQSLYLK 7 1 A0A494BZT8;Q9Y6A5;H0Y8F2;A0A494C117 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 KQS(0.999)LY(0.001)LK 85.53299999999999 0.028235000000000003 5447500.0 20185.0 9379.5 16541.0 18723.0 11464.0 12276.0 9232.1 9700.3 18733.0 9637.4 True False 19897.158198524357 9357.782344024765 15181.06283010647 20099.951878097057 10789.710059091189 11750.984096753697 9710.092964987773 10151.011350686178 16623.09227276475 11303.2117489717 1.7603101348901549 0.8278870246658947 1.3430751513159571 1.7782513788548315 0.9545702848637488 1.039614611999349 0.8590560966772245 0.8980643357061463 1.470652115694198 1.0 13.464445144751739 -6.319490309553442 24.998008979671557 1.0231301939793143 1.3785404012085167 0.2926228015625373 0.29297426103937385 378.1418239342615 162835.13276354803 0.09074386166716768 0.10289390287683188 4.791921450405446e-07 6.319490309553442 0.35541020722920247 KQS(ph)PVPALPIVVQLMEMGFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KQSPVPALPIVVQLMEMGFSR 21 1 O95714 O95714 HERC2 E3 ubiquitin-protein ligase HERC2 1 KQS(1)PVPALPIVVQLMEMGFSR 51.966 0.031907 0.0 7406.4 9097.5 9568.6 8558.1 10940.0 8330.8 10125.0 7073.2 7176.2 6742.8 True False 8660.157236932057 10000.63967671707 9796.751713117583 8078.61740273456 8796.385533447106 7893.9181824647685 9165.88670134797 6887.53599467488 7281.138348963417 7965.216264024566 1.0872469685532882 1.2555390017325243 1.229941710103374 1.0142370445385365 1.1043498684620243 0.9910488203714166 1.1507392137921368 0.8647016937610218 0.9141168434872469 1.0 12.959497817636793 -6.63410369144077 0.6291321629341228 0.9387711345561865 1.1986443967819338 0.47744180080729337 0.08791748174464428 0.6988443797515315 0.610440013279076 0.06826573276530061 0.08522048296844621 2.3221822897146365e-07 6.63410369144077 0.25987326222574725 KQS(ph)SSEISLAVER ddPTM_PC-9_AZD4547_30min_R2 2 KQSSSEISLAVER 13 1 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 KQS(0.958)S(0.034)S(0.007)EISLAVER;KQS(0.883)S(0.089)S(0.028)EISLAVER 108.66 0.0012827 35579000.0 65796.0 49578.0 65012.0 68268.0 68349.0 61935.0 55782.0 86016.0 79680.0 69321.0 True False 86717.75935818181 65603.11894936848 64149.89840191383 52529.86733008593 58859.92113961847 58062.194659130815 60746.48993594718 72724.20365104335 83891.72213005599 66894.09288967031 1.29634405090457 0.9807012266026081 0.958977028176725 0.7852691480057056 0.8798971418402705 0.8679719262341129 0.9080994645691289 1.0871543436725983 1.254097611704223 1.0 16.029591198263063 -7.879162426838525 4.876527004248284 1.1397528018513925 0.9429083187013372 0.21380781147987704 0.13975004195429644 0.29683690847336525 11.2310792942925 0.08288191529976524 0.03839399088238159 1.3208015598807882e-08 7.879162426838525 -0.19684448315005532 KQS(ph)SSEISLAVER ddPTM_PC-9_Lapatinib_30min_R1 2 KQSSSEISLAVER 13 1 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 KQS(0.446)S(0.446)S(0.102)EIS(0.007)LAVER;KQS(0.785)S(0.174)S(0.041)EISLAVER 74.812 0.0087385 37556000.0 46777.0 66149.0 63304.0 48696.0 54210.0 58171.0 47428.0 51119.0 63043.0 74745.0 True False 46109.951402148814 65995.8360546825 58099.38948050658 52277.26628509397 51021.474380960695 55683.16193322408 49883.589773013744 53494.17535908443 55942.43346777925 87664.5736585478 0.5259815850099994 0.7528221868931376 0.6627465013039684 0.5963328640450946 0.5820078995614417 0.6351843123096584 0.5690279173353375 0.6102142875575194 0.6381418528957226 1.0 16.419706329030042 -8.832461046042178 4.203179393447812 0.9999997641422907 0.6201846805566731 0.7973784411716516 0.05766175360559459 4.7136528191415366 63.750059423449336 0.055897462545193045 0.014608344455501104 1.4707503281488752e-09 8.832461046042178 -0.37981508358561766 KQS(ph)TQDEDAVSLCSLDISEPSNK ddPTM_PC-9_AZD4547_30min_R2 1 KQSTQDEDAVSLCSLDISEPSNK 23 1 C9J5K8;C9J609;C9JNF2;E9PG37;Q9NR81-2 C9J5K8 ARHGEF3 1 KQS(0.498)T(0.498)QDEDAVS(0.004)LCS(0.001)LDISEPSNK 53.196999999999996 0.007231699999999999 3097600.0 10648.0 15007.0 10862.0 13354.0 11079.0 11147.0 10726.0 14475.0 14889.0 13468.0 True False 14033.84250784122 19857.71927212016 10717.962782895282 10275.441617243323 9540.872087460424 10449.976327849052 11680.59322098472 12238.221352409451 15676.002143504058 12996.48941934015 1.079817945833694 1.5279294762914803 0.824681376414297 0.7906320919210983 0.7341114803865879 0.8040614654214531 0.8987498734545009 0.9416559316547193 1.2061720390566786 1.0 13.66583435808941 -5.275851201920106 24.921806367973357 0.8846215435849674 1.3038737194642764 0.4970707050962161 0.16190476165018877 519.5120736161653 898372.1245978333 0.04283412770913777 0.08982894885337026 5.298449484000408e-06 5.275851201920106 0.4192521758793091 KQS(ph)TQDEDAVSLCSLDISEPSNKR ddPTM_PC-9_AZD4547_30min_R2 1 KQSTQDEDAVSLCSLDISEPSNKR 24 2 C9J5K8;C9J609;C9JNF2;E9PG37;Q9NR81-2 C9J5K8 ARHGEF3 1 KQS(0.617)T(0.337)QDEDAVS(0.043)LCS(0.003)LDISEPSNKR 60.379 0.034845 0.0 5689.9 6017.3 8187.9 8838.5 7556.1 6991.5 5985.3 6748.2 5841.6 7270.4 True False 7499.169842727814 7962.2745502851085 8079.3230961211775 6800.920378463761 6507.0659427800065 6554.320399762864 6517.980104937519 5705.420748209288 6150.375050137235 7015.865508937531 1.0688873430048795 1.1348955506832257 1.1515789585517147 0.9693629916080988 0.9274787172716804 0.9342140882565804 0.9290343574337687 0.813216949632392 0.876638105776437 1.0 12.776405376879085 -5.90982999690749 3.4619441352773026 0.9078119179798283 1.120165058776195 0.7730639387790388 0.04945984984136551 0.10906344561269751 2.5811147937342915 0.0151994115034734 0.02356633879476927 1.230750449592894e-06 5.90982999690749 0.2123531407963668 KQS(ph)TQDEDAVSLCSLDISEPSNKR ddPTM_PC-9_Lapatinib_30min_R1 2 KQSTQDEDAVSLCSLDISEPSNKR 24 2 C9J5K8;C9J609;C9JNF2;E9PG37;Q9NR81-2 C9J5K8 ARHGEF3 1 KQS(0.808)T(0.192)QDEDAVSLCSLDISEPSNKR;KQS(0.499)T(0.499)QDEDAVS(0.001)LCSLDISEPSNKR 77.668 6.6852e-05 12676900.0 17026.0 18738.8 21494.6 16814.9 44965.0 59593.0 69664.0 63275.0 60539.0 55809.0 True False 16783.20611781399 18695.41145990844 19727.396959555434 18051.523838862042 42320.24710459132 57044.34630806803 73270.86105143014 66214.98749674416 53720.46031606818 65455.511289181886 0.25640630998459285 0.28562012719314456 0.3013863396834525 0.2757831003582046 0.6465497904007018 0.8714979867172162 1.1193994150885187 1.0116029375159399 0.8207171444850786 1.0 15.998227050326909 -6.538643040914731 1.957841068615192 0.9884875761114259 0.27329433370736345 0.9505806908677695 0.07373936173749568 0.06775157716596977 0.5245841288440378 0.028583981144492482 0.03064098804612485 2.893056791723551e-07 6.538643040914731 -0.7151932424040625 down KQS(ph)VFSAPSLSAGASAAEPLDR ddPTM_PC-9_AZD4547_30min_R2 3 KQSVFSAPSLSAGASAAEPLDR 22 1 Q14573 Q14573 ITPR3 Inositol 1,4,5-trisphosphate receptor type 3 1 KQS(1)VFSAPSLSAGASAAEPLDR;KQS(0.998)VFS(0.002)APSLSAGASAAEPLDR;KQS(0.982)VFS(0.018)APSLSAGASAAEPLDR 114.73 7.657999999999999e-07 125191300.0 325882.0 360005.0 601585.0 472595.0 487228.0 254243.0 445484.0 400218.0 374512.0 284897.0 True False 429505.697233313 476369.57596852235 593607.589831344 363645.52426996425 419584.8023674663 238345.14501850898 485131.21298313915 338373.5041947222 394307.9397385982 274922.84274589736 1.562277230016466 1.7327391613246774 2.159178858702538 1.3227184785298853 1.5261911239411834 0.8669528608024907 1.7646086012268207 1.2307944324126983 1.434249463596027 1.0 18.068667256686382 -5.793291679262206 24.542091616900176 1.3260451595892606 1.809532412775462 0.4185151378986247 0.275598348113418 149.68414196426704 115330.47749569154 0.07474729611211026 0.11088038085709334 1.6095642624566246e-06 5.793291679262206 0.48348725318620134 KQS(ph)VFSAPSLSAGASAAEPLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KQSVFSAPSLSAGASAAEPLDR 22 1 Q14573 Q14573 ITPR3 Inositol 1,4,5-trisphosphate receptor type 3 1 KQS(1)VFSAPSLSAGASAAEPLDR;KQS(0.994)VFS(0.006)APSLSAGASAAEPLDR 91.691 9.0361e-05 55118000.0 69024.0 67709.0 61225.0 51085.0 88171.0 44279.8 46332.0 43298.0 39789.0 38061.0 True False 80708.39991385811 74430.70204680788 62684.836197105484 48222.8730698046 70894.52549081949 41957.68933786714 41943.0975453683 42161.473378023096 40370.838851607434 44961.15800928977 1.7950694218592487 1.6554445068214032 1.3941997709256886 1.0725451746558863 1.5767949187645796 0.9331985917533071 0.9328740495674536 0.9377310381843766 0.8979047835748827 1.0 15.456391573309912 -4.814426068147841 0.40658453535410993 0.8887097997871004 2.4873290512562076 0.760630103316114 0.16198855203051354 2.650071107746795 0.3522969858336071 0.13490036750456846 2.0740361372853813 1.5331121725508013e-05 4.814426068147841 1.598619251469107 KQS(ph)VFSAPSLSAGASAAEPLDR ddPTM_PC-9_Lapatinib_30min_R1 4 KQSVFSAPSLSAGASAAEPLDR 22 1 Q14573 Q14573 ITPR3 Inositol 1,4,5-trisphosphate receptor type 3 1 KQS(0.997)VFS(0.003)APSLSAGASAAEPLDR;KQS(1)VFSAPSLSAGASAAEPLDR;KQS(0.952)VFS(0.048)APSLSAGASAAEPLDR;KQS(0.735)VFS(0.265)APSLSAGASAAEPLDR 107.36 1.4119000000000002e-05 108214800.0 262542.0 266710.0 135174.0 90345.0 83002.0 112245.0 104426.0 94156.0 152869.0 32018.3 True False 258798.1029356933 266092.44938161416 124060.51550672935 96989.27268208501 78119.9855482107 107444.54300587486 109832.66731965792 98530.83149337707 135651.28343806506 37552.62049329699 6.891612343854614 7.085855684268711 3.303644695817532 2.582756447034029 2.0802805376033566 2.861172977929818 2.924767056915846 2.6238070792147377 3.6122987332476124 1.0 15.196625964806264 -5.310776731832478 3.7820471562028932 2.6265304075080973 7.069123874638749 0.8805221300944346 0.646903627703692 0.06321480417035114 1.8736830682330674 0.1641436470476448 0.40079767309600806 4.889036371511815e-06 5.310776731832478 4.442593467130652 KQSAGPNS(ph)PTGGGGGGGSGGTR ddPTM_PC-9_AZD4547_30min_R2 3 KQSAGPNSPTGGGGGGGSGGTR 22 1 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 KQS(0.002)AGPNS(0.954)PT(0.037)GGGGGGGS(0.002)GGT(0.005)R;KQS(0.002)AGPNS(0.979)PT(0.013)GGGGGGGS(0.006)GGT(0.001)R;KQSAGPNS(0.841)PT(0.157)GGGGGGGSGGT(0.001)R 101.75 3.4648000000000004e-05 23783400.0 9043.880000000001 6911.3 11725.1 17520.0 13355.5 9388.720000000001 9065.02 10445.18 6354.39 9816.72 True False 11919.645715609986 9145.24256716226 11569.617512955754 13481.034681301702 11501.319357710772 8801.641854203186 9871.789218729333 8831.117437358218 6690.270082655705 9473.039620777017 1.2582704382938374 0.965396845496581 1.2213205028278735 1.4230949326691333 1.214110762556632 0.9291254134416087 1.0420930993551158 0.9322369367049954 0.7062432282012288 1.0 13.209611703196032 -6.762817703086974 8.926152019486585 0.9249302640331999 1.214468339188906 0.5536292654709007 0.13220219403021394 0.09203778170604046 84.86589249181024 0.0482266244571428 0.045131960243250425 1.7265624716772732e-07 6.762817703086974 0.28953807515570607 KQSAGPNS(ph)PTGGGGGGGSGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KQSAGPNSPTGGGGGGGSGGTR 22 1 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 KQS(0.001)AGPNS(0.843)PT(0.116)GGGGGGGS(0.014)GGT(0.027)R;KQSAGPNS(0.548)PT(0.391)GGGGGGGS(0.017)GGT(0.043)R;KQSAGPNS(0.599)PT(0.338)GGGGGGGS(0.031)GGT(0.031)R 76.611 0.00036165 12079700.0 10500.2 9372.599999999999 11439.4 13539.199999999999 14487.5 17108.2 15832.6 13355.300000000001 12747.1 9595.6 True False 12277.67647159673 10303.049786644506 11712.158680166089 12780.642518678647 11648.778374388941 16211.015874735162 14332.821509902411 13004.737526110035 12933.502222356055 11335.206321272195 1.083145390001049 0.9089424131000867 1.0332550064118804 1.127517414014236 1.0276635505547245 1.430147402285284 1.2644517535604753 1.1472872356725186 1.141002806281913 1.0 13.468523030528214 -6.137671251935916 1.6479389010341545 1.20122524433789 1.0004113193434703 0.2597922699156394 0.119993948279057 0.45178528917745653 2.4416257603694342 0.04251030267903165 0.06335642223182876 7.283309208635985e-07 6.137671251935916 -0.20081392499441963 KQSAGPNS(ph)PTGGGGGGGSGGTR ddPTM_PC-9_Lapatinib_30min_R1 2 KQSAGPNSPTGGGGGGGSGGTR 22 1 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 KQS(0.01)AGPNS(0.654)PT(0.291)GGGGGGGS(0.022)GGT(0.022)R;KQSAGPNS(0.428)PT(0.428)GGGGGGGS(0.042)GGT(0.102)R 74.392 0.00043853 8690500.0 8566.5 7350.900000000001 8561.9 6399.54 5979.2 10245.8 7709.9 6703.9 9649.6 4336.9 True False 8444.340139096299 7333.8794426879485 7857.973631889765 6870.183519839625 5627.515211559487 9807.611018126343 8109.080897169569 7015.387667790175 8562.760433207213 5086.527386443994 1.6601385380527287 1.4418244286334383 1.544860183557037 1.35066283888478 1.1063570062666466 1.9281545685302743 1.5942273148437034 1.3792096522446236 1.683419705166173 1.0 12.312465337402259 -11.199895787816084 2.931301566426202 0.9421185106662705 1.5121134915325003 0.3534946170153356 0.211061853732002 154219388.52746162 145623069.93929392 66525087.45928791 0.05326135062677523 6.3110876554403505e-12 11.199895787816084 0.5699949808662298 KQSAGPNSPT(ph)GGGGGGGSGGTR ddPTM_PC-9_Lapatinib_30min_R1 1 KQSAGPNSPTGGGGGGGSGGTR 22 1 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 KQSAGPNS(0.331)PT(0.46)GGGGGGGS(0.104)GGT(0.104)R 78.942 0.00052023 8021600.0 7401.4 4382.2 4851.0 5202.1 5615.2 5392.9 4201.9 5423.5 5309.2 4228.1 True False 7295.854678749471 4372.0532851415655 4452.169505401515 5584.679787696882 5284.924975907957 5162.258238463915 4419.453821945398 5675.49560946017 4711.22198764547 4958.921451410884 1.4712583674165065 0.8816540709467486 0.8978100478148952 1.1261883944759723 1.0657408123301326 1.0410042363133578 0.8912127093055688 1.1445020182454009 0.9500497303309896 1.0 12.275810658116418 -4.752021089628157 24.99976287965006 1.0050295084692753 1.4712592846800714 0.7094391365349014 0.0904610523070299 212.5738026470268 564212.6166027503 0.022808153640334946 0.2840336321696359 1.7700230027391405e-05 4.752021089628157 0.4662297762107961 KQSEPFFK ddPTM_PC-9_Lapatinib_30min_R1 1 KQSEPFFK 8 1 P11413;P11413-2;P11413-3;E7EUI8;E7EM57;E9PD92 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 59.931000000000004 0.04543 7156100.0 147830.0 122740.0 116680.0 104640.0 132930.0 101130.0 102880.0 124930.0 132000.0 114890.0 False True 145721.91709129847 122455.80307112314 107087.02079782487 112335.57466880698 125111.31875043546 96804.90564554418 108206.62300429399 130734.70387938787 117132.76997837752 134748.58341869785 1.081435614343371 0.9087724706583524 0.7947172287895485 0.8336679452855694 0.9284796587559145 0.7184113048873167 0.8030260523635243 0.9702120835894962 0.8692690268543785 1.0 17.039910580768492 -11.160353284600221 7.771874777298143 1.0001933639759497 0.872978261791535 0.12145279170435663 0.09681870627745656 0.0003340188327282075 1.5580523848859483e-05 0.09652798259349848 0.023376168488891354 6.9126841750423595e-12 11.160353284600221 -0.12721510218441467 KQSFDDNDS(ph)EELEDKDSK ddPTM_PC-9_Lapatinib_30min_R1 2 KQSFDDNDSEELEDKDSK 18 2 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 KQS(0.003)FDDNDS(0.974)EELEDKDS(0.023)K;KQSFDDNDS(0.999)EELEDKDS(0.001)K 85.881 0.0050598 49148000.0 61650.0 57359.0 39399.0 56551.0 47250.0 45089.0 43791.0 40964.0 39890.0 41460.0 True False 60770.85969477467 57226.188759626486 36159.7663045381 60709.9491886058 44470.847897074156 43160.64857759263 46058.2837089914 42867.336986434275 35397.16813967787 48626.30575802255 1.2497527572254132 1.1768565978340868 0.7436256104767393 1.2485001326383847 0.9145430072021704 0.8875987576019349 0.9471886253952684 0.88156680459654 0.7279427788700135 1.0 15.56944937073477 -1.5228787452809331 0.44234136945104074 0.8838997891168998 9.026116022544596 0.3816486046749954 0.1421875992074714 89.27671219386781 1.093679526162175 0.08931947381175877 653.2755821383294 0.029999999999958858 1.5228787452809331 8.142216233427696 KQSLGELIGTLNAAK ddPTM_PC-9_AZD4547_30min_R2 4 KQSLGELIGTLNAAK 15 1 P60174;P60174-3 P60174 TPI1 Triosephosphate isomerase 0 ;;; 156.96 0.00010523 41776500.0 265144.6 221759.6 296990.0 345147.0 356198.0 291168.6 297182.5 320945.7 283159.3 320160.0 False True 349455.06744971516 293439.0539546649 293051.71855018154 265578.69161799294 306746.05612503213 272961.7814132004 323631.1667812125 271350.9166634886 298126.5225168315 308951.2958491203 1.1311008309231216 0.9497906559937818 0.9485369457498457 0.8596134574806612 0.9928621768100137 0.8835107186166464 1.047515162193271 0.8782967422671234 0.9649628485857681 1.0 18.23701989905487 -4.761003330083813 5.886208999154893 0.9428259307990895 1.1385765108430412 0.4874433578289106 0.05644619003189058 0.10884047332204634 13.880657286974008 0.012978836545618391 0.08619899091010534 1.7337907033404782e-05 4.761003330083813 0.19575058004395174 KQSLGELIGTLNAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KQSLGELIGTLNAAK 15 1 P60174;P60174-3 P60174 TPI1 Triosephosphate isomerase 0 ;; 118.2 7.3787e-05 26867000.0 243886.0 240919.0 263185.0 319514.0 302209.0 293299.0 313341.0 282196.0 264324.0 225236.0 False True 285171.0828319311 264835.8461417975 269460.3285346712 301612.66645836475 242993.315875458 277917.88411661924 283659.0720876125 274788.6540113779 268189.2384481216 266069.5038328046 1.071791688727806 0.9953634006406749 1.012744131337943 1.1335860070904447 0.9132700755820274 1.0445311473623826 1.066108922674058 1.032770197459579 1.0079668454474549 1.0 18.021443636467474 -6.239725071826667 24.9982146159709 1.0168675647252636 1.0463259189976089 0.12913409675937437 0.0515041794852908 2500.6600449713083 2878842.661832242 0.015404563177707916 0.01986516306173815 5.758043323349516e-07 6.239725071826667 0.029458354272345222 KQSLGELIGTLNAAK ddPTM_PC-9_Lapatinib_30min_R1 3 KQSLGELIGTLNAAK 15 1 P60174;P60174-3 P60174 TPI1 Triosephosphate isomerase 0 ;; 161.82 7.4172e-05 28841400.0 249813.0 208384.0 230809.0 214050.0 230986.0 215824.0 186753.0 200114.0 225649.0 190471.0 False True 246250.62080990674 207901.49965107485 211832.7749685048 229791.9510498675 217399.8576159489 206593.71063031704 196422.156550553 209412.02699207343 200234.03343068887 223393.65856334602 1.1023169699335014 0.9306508563765781 0.948248828238054 1.0286413344392547 0.9731693326214204 0.9247966659346101 0.879264692712193 0.9374125852041233 0.8963281890739528 1.0 17.76922870730789 -6.6839750128149165 3.795934175311675 0.9202317915848265 0.9941080260431718 0.3003660550838744 0.05291243908275708 0.2886439899474557 8.126942173040565 0.017914894221323363 0.017512859567112782 2.0702604580481825e-07 6.6839750128149165 0.07387623445834535 KQSTQDEDAVS(ph)LCSLDISEPSNK ddPTM_PC-9_Lapatinib_30min_R1 1 KQSTQDEDAVSLCSLDISEPSNK 23 1 C9J5K8;C9J609;C9JNF2;E9PG37;Q9NR81-2 C9J5K8 ARHGEF3 1 KQS(0.256)T(0.256)QDEDAVS(0.44)LCS(0.045)LDIS(0.002)EPS(0.001)NK 59.538999999999994 0.0027081999999999996 3638000.0 2910.3 5234.5 4339.4 4712.6 14635.0 21634.0 25274.0 24312.0 18974.0 18578.0 True False 2868.798588316344 5222.379836856721 3982.6312825684035 5059.180324772752 13774.198073517051 20708.764251317156 26582.564053368224 25441.62427531957 16836.94831492224 21789.182546371052 0.1316615977772942 0.2396776393856271 0.1827802063750071 0.2321877066294692 0.6321576334588613 0.9504149229667251 1.2199890471703585 1.1676263770417044 0.7727205129926457 1.0 14.411324452165791 -6.520232001260194 1.9821287742222116 1.057688775803317 0.1863858225031984 0.9192764226482185 0.11543650502202443 0.08576911727154905 0.678325110758371 0.04398400551180981 0.04772593999556592 3.0183388850392173e-07 6.520232001260194 -0.8713029533001186 down KQTDFEHR ddPTM_PC-9_AZD4547_30min_R2 3 KQTDFEHR 8 1 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 0 ;; 72.87899999999999 0.012490000000000001 8431140.0 27364.9 21414.6 32512.3 43051.9 40862.0 37685.0 26712.4 32985.6 31050.0 39724.0 False True 36066.36897472057 28336.45066467275 32081.16565884058 33126.94960022449 35189.01662946183 35328.550992643 29089.75185122432 27888.43345368133 32691.239610168646 38333.27485104457 0.9408632347449379 0.7392128842313245 0.8369012505062916 0.8641826123374323 0.9179757473422061 0.9216157797611261 0.7588642495132825 0.7275254608965761 0.8528162474299485 1.0 15.226309633872114 -10.188652535859458 24.45866699842702 0.9999999999433987 0.8366514819081651 0.3014299897085958 0.07291474813883148 0.0 0.0 0.07392769095103366 0.01793009873230181 6.476605795659698e-11 10.188652535859458 -0.16334851803523365 KQTDFEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KQTDFEHR 8 1 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 0 57.59 0.032137 2016300.0 11600.0 10955.0 14097.0 13283.0 15657.0 13525.0 15041.0 12170.0 14054.0 10267.0 False True 13563.650889556577 12042.540000927236 14433.12594317022 12538.796574067032 12589.123244714936 12815.72519059825 13616.207592590108 11850.550395180871 14259.513162444167 12128.325826472723 1.1183448633900437 0.9929268205049174 1.1900344820607283 1.033843974301743 1.0379934893599594 1.0566771847953762 1.1226782482104627 0.9770969682653523 1.175719828644417 1.0 13.566092796574964 KRDLQT(ph)ST(ph)HVET(ph)LLT(ph)FSALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KRDLQTSTHVETLLTFSALK 20 2 P78536;A0A3B3ISQ1;A6H8L4;P78536-2 P78536 ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 4 KRDLQT(0.534)S(0.534)T(0.935)HVET(0.698)LLT(0.65)FS(0.65)ALK 40.179 0.046431 0.0 976.69 853.61 692.57 2146.6 2256.3 621.95 853.22 857.33 933.09 887.64 True False 1142.0243264931914 938.350759488041 709.0834953863517 2026.3329613710991 1814.194211985074 589.3338471195998 772.396824822135 834.825995916222 946.7346760171505 1048.5621054456258 1.0891337008672894 0.894892877221854 0.6762436785611283 1.9324873089037802 1.7301733512618827 0.5620400013112626 0.7366247748328422 0.7961626608291661 0.9028885090357143 1.0 10.034196598232903 -6.783441438439584 24.999019315626256 0.7828709711702055 1.2484678537503977 0.294236159510767 0.3592210734872654 353.61957065456363 401784.2351809003 0.14049165119319598 0.123999882923979 1.6464879686979382e-07 6.783441438439584 0.46559688258019216 KRDS(ph)QGTYSSR ddPTM_PC-9_Lapatinib_30min_R1 1 KRDSQGTYSSR 11 2 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 KRDS(0.816)QGT(0.163)Y(0.001)S(0.02)SR 63.292 0.016447 16990000.0 17919.0 18360.0 17295.0 16137.0 20798.0 16450.0 24560.0 24328.0 23199.0 17504.0 True False 17663.471774057845 18317.488548035046 15873.07186063064 17323.76881145395 19574.702530441253 15746.471846822933 25831.596626997074 25458.367693730434 20586.084323699863 20529.543077386097 0.8603928352168093 0.8922501820419133 0.7731819359445609 0.8438458053426721 0.953489439908839 0.7670152125386629 1.2582645668062309 1.2400844771734634 1.0027541405135338 1.0 14.32541389753055 -7.258060058025112 24.9999999870012 1.145282839205391 0.8515133414426764 0.6729170896576665 0.09415188917268348 164.87978064602223 1219775.3692196913 0.036410052301874746 0.027030904085288854 5.520010984806734e-08 7.258060058025112 -0.29376949776271466 KREEGS(ph)DIEDEDMEELLNDTR ddPTM_PC-9_Lapatinib_30min_R1 4 KREEGSDIEDEDMEELLNDTR 21 2 Q8NHQ9-2;F5H5U2;Q8NHQ9 Q8NHQ9-2 DDX55 ATP-dependent RNA helicase DDX55 1 KREEGS(1)DIEDEDMEELLNDTR;KREEGS(1)DIEDEDMEELLNDTR;KREEGS(1)DIEDEDMEELLNDTR;KREEGS(1)DIEDEDMEELLNDTR 75.608 0.0017465999999999998 21943400.0 84075.3 76951.6 93814.8 76747.7 79710.7 69009.1 72948.4 73522.1 77153.9 74675.4 True False 82876.37080447823 76773.42329809214 86101.70927960036 82391.981880822 75022.27334326592 66057.74166106917 76725.31121273755 76938.20517162174 68464.01531541468 87582.9433912841 0.946261539010183 0.8765796207042331 0.9830876417904088 0.9407309082172421 0.85658543134475 0.7542306652786342 0.8760302890251224 0.8784610586549243 0.7817048921220423 1.0 16.41836231466376 -6.287158404533073 6.362016963819746 0.8471577582956287 0.9357984224743671 0.24457707534242357 0.06635575519551644 0.23411061881381212 35.764609805631736 0.019751023032278776 0.02302262863210276 5.162280459552586e-07 6.287158404533073 0.0886406641787384 KREPEDEGEDDD ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KREPEDEGEDDD 12 2 P39687 P39687 ANP32A Acidic leucine-rich nuclear phosphoprotein 32 family member A 0 ;; 82.494 0.025240000000000002 111520000.0 198816.0 221557.0 213909.0 243882.0 239365.0 229156.0 229970.0 210648.0 209946.0 187370.0 False True 232471.62200500676 243551.71474079782 219009.4018143998 230218.0822161126 192463.14654603027 217138.6559539173 208185.57676138193 205118.7132000046 213016.06307118962 221338.69777989612 1.0502981373649423 1.1003575840271311 0.9894763275068483 1.0401167284586013 0.8695413340572723 0.9810243673243464 0.9405746886990637 0.9267187132544666 0.9623986460922315 1.0 17.755896181402314 -5.749185641807293 1.5807382964247745 0.946318825537922 1.071072819495427 0.53305858874076 0.04325584101374981 0.27416589976320804 1.385215150822473 0.013107824045646591 0.029512478027374115 1.781617041659847e-06 5.749185641807293 0.12475399395750508 KREPEDEGEDDD ddPTM_PC-9_Lapatinib_30min_R1 1 KREPEDEGEDDD 12 2 P39687 P39687 ANP32A Acidic leucine-rich nuclear phosphoprotein 32 family member A 0 79.97399999999999 0.030994999999999998 46487000.0 51654.0 45389.0 55260.0 42820.0 50382.0 36051.0 40529.0 44562.0 48281.0 32298.0 False True 50917.404487816515 45283.90455919185 50716.73610976866 45969.12564333257 47418.62981482311 34509.18276898561 42627.39331007998 46632.513201579066 42843.08535853067 37880.66626562018 1.3441528227297377 1.195435799403843 1.3388554402433588 1.2135247390052728 1.2517897515931342 0.9109972492829549 1.1253073800543958 1.231037302105267 1.131001367771989 1.0 15.20917408547858 -6.5631391684286715 24.9936165466957 1.0952310235838272 1.2672197060947579 0.5165714836754983 0.09095325341670821 141.17352778770564 87639.46182751654 0.030527824922822248 0.030527836215416077 2.7343923576632836e-07 6.5631391684286715 0.1719886825109307 KRES(ph)ESESDETPPAAPQLIK ddPTM_PC-9_Lapatinib_30min_R1 1 KRESESESDETPPAAPQLIK 20 2 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 KRES(0.74)ES(0.101)ES(0.159)DETPPAAPQLIK 100.94 0.00082204 7265400.0 16624.0 25622.0 23899.0 23258.0 33457.0 21084.0 22624.0 32770.0 27622.0 26316.0 True False 16386.93871153177 25562.673833211004 21934.116472807847 24968.47090641357 31489.125038992832 20182.28646920453 23795.360019917825 34292.61383276661 24510.919487445037 30864.68553613414 0.5309284195475482 0.8282175369415015 0.710654137302937 0.8089656665117256 1.020231520004558 0.6538957426142109 0.7709574747508747 1.1110631207507136 0.7941412349317288 1.0 14.913669472132742 -3.2615133731045454 0.25369054465055607 0.959344218714289 1.9112063623358507e-28 0.35351846466860326 0.13537970003265687 26.790577664460702 0.7830746008947024 0.1809083934275992 9.194300311990089 0.0005476292377133159 3.2615133731045454 -0.959344218714289 KRESESES(ph)DETPPAAPQLIK ddPTM_PC-9_Lapatinib_30min_R1 1 KRESESESDETPPAAPQLIK 20 2 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 KRES(0.157)ES(0.047)ES(0.758)DET(0.039)PPAAPQLIK 57.93600000000001 0.0057866 7338400.0 23333.0 30478.0 32347.0 24932.0 33648.0 31655.0 28670.0 31683.0 27600.0 35206.0 True False 23000.26714125186 30407.430063562737 29687.554523030885 26765.582450713875 31668.890794513274 30301.18944140909 30154.39231661262 33155.107844478 24491.39735911531 41291.31019095376 0.5570243965349115 0.7364123328356992 0.7189782640884798 0.6482134455636085 0.7669626041910242 0.733839379309586 0.7302842214781294 0.8029560624535894 0.5931368427364887 1.0 15.333550576121247 -14.522878745280336 0.293628220641664 3.3141428533721173 0.6902514764052822 0.5902185051593754 0.07440322945432874 176.8390208009438 1.6543901422568736 251.43187844935588 0.07452231284160718 3.0000000000000132e-15 14.522878745280336 -2.623891376966835 KRIPFS(ph)KT(ph)Y(ph)SK ddPTM_PC-9_Lapatinib_30min_R1 1 KRIPFSKTYSK 11 3 F8VSD7;Q8NA57 F8VSD7 C12orf50 Uncharacterized protein C12orf50 3 KRIPFS(0.987)KT(0.993)Y(0.998)S(0.021)K 62.924 0.03935 0.0 17229.0 12941.0 20890.0 13451.0 16479.0 16704.0 16363.0 16556.0 17727.0 14643.0 True False 16983.31130058836 12911.035909592676 19172.504837731954 14440.231411220604 15509.737618960533 15989.608858925852 17210.19607522611 17325.252200649502 15730.398586414394 17174.02303942895 0.9888953369631132 0.7517770227715951 1.116366549277056 0.8408182158640422 0.9030928620133168 0.9310345527204743 1.0021062645434977 1.0088056922290922 0.9159413930154738 1.0 14.067940411852833 -7.133161936792856 5.0243980928323 0.9821085916795522 0.9173515880999171 0.09262825270970654 0.09167740766178488 0.558648548692246 20.474715120191828 0.03407004032598037 0.026239466685044097 7.359326367378429e-08 7.133161936792856 -0.0647570035796351 KRKPS(ph)PEPEGEVGPPK ddPTM_PC-9_AZD4547_30min_R2 1 KRKPSPEPEGEVGPPK 16 3 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 KRKPS(1)PEPEGEVGPPK 74.51899999999999 0.010814 34743000.0 77053.0 41576.0 65109.0 113190.0 91260.0 59238.0 55367.0 57303.0 49797.0 71870.0 True False 101554.25119803617 55014.62893700724 64245.61211853517 87095.7942680674 78590.1242622654 55533.83849548058 60294.555739908705 48448.1380419426 52429.167757409625 69353.85317552535 1.4642914062902304 0.7932454567127302 0.9263452451003421 1.2558176695336531 1.133176033685746 0.8007318404491794 0.8693757156839034 0.6985644751319992 0.7559661843837053 1.0 16.081688417870446 -6.765230409302901 24.939706344921593 0.8088658783188428 1.0941131164879319 0.3786663918926587 0.18401040916693048 106.85751570619541 702968.4571434631 0.06367247857250634 0.05829585326054957 1.7169972148773616e-07 6.765230409302901 0.28524723816908903 KRKPS(ph)PEPEGEVGPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KRKPSPEPEGEVGPPK 16 3 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 KRKPS(1)PEPEGEVGPPK;KRKPS(1)PEPEGEVGPPK 87.352 0.0035183 54498000.0 150112.0 55688.0 102878.0 185159.0 167842.0 219160.0 195799.0 186753.0 193995.0 175390.0 True False 175522.9967528554 61216.33661082937 105331.0016869875 174785.14152357777 134954.56496387805 207666.86379087003 177251.5012579978 181850.93163115985 196831.80987251727 207186.81861352353 0.8471726045481092 0.29546443649496557 0.5083865971390147 0.8436113006282204 0.6513665582925712 1.002316967751901 0.8555153384957097 0.8777147737876895 0.9500209095815019 1.0 17.660572695000766 -6.199966235195464 1.2350442863322642 0.921257658280303 0.5331353169093404 0.4855733028609366 0.15640612891512556 0.37726785551518716 1.1748992475684825 0.060707031164265915 0.09343419631889056 6.310064010085999e-07 6.199966235195464 -0.3881223413709627 KRKPS(ph)PEPEGEVGPPK ddPTM_PC-9_Lapatinib_30min_R1 1 KRKPSPEPEGEVGPPK 16 3 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 KRKPS(1)PEPEGEVGPPK 73.80199999999999 0.011470000000000001 14778000.0 132790.0 55319.0 72213.0 49230.0 55332.0 53258.0 32785.0 41727.0 57590.0 40559.0 True False 130896.39024929654 55190.91225428926 66275.92589024125 52850.53842646573 52077.48054689753 50980.27949046176 34482.44688176297 43665.7887519027 51103.60775041487 47569.56910852961 2.751683328277736 1.1602146769160682 1.3932420901066653 1.1110157064043953 1.0947646052475932 1.0716994172083132 0.7248845749073641 0.917935343334297 1.0742920044918292 1.0 15.537751336785849 -2.8147093866569377 1.2057970428917222 1.0096718527626303 199.99999999982694 0.900717358383122 0.16774631185908154 51.211251686907985 0.8496541280326003 0.051395351872018165 27423.312432167284 0.0015321123500257976 2.8147093866569377 198.9903281470643 up KRPAS(ph)PSHNGSSGGGYGASK ddPTM_PC-9_Lapatinib_30min_R1 1 KRPASPSHNGSSGGGYGASK 20 2 K7ELX9;K7EQ79;K7ENM4;K7ENP7;Q6PI98;Q6PI98-3;Q6PI98-4 K7ELX9 INO80C INO80 complex subunit C 1 KRPAS(0.465)PS(0.465)HNGS(0.053)S(0.017)GGGYGASK 42.638999999999996 0.033987 7164000.0 47203.0 25762.0 69710.0 36734.0 55468.0 62389.0 37867.0 42460.0 73186.0 35711.0 True False 46529.876564029975 25702.349671812557 63978.71288838172 39435.540901031716 52205.481294283796 59720.76790586232 39827.567975346035 44432.84660785078 64943.02199725413 41883.59876808356 1.1109331082477805 0.613661443328467 1.527536190064337 0.9415509187592225 1.2464421117047322 1.4258747973531627 0.9509108373394056 1.0608650620946596 1.550559739549947 1.0 15.354097787954942 -5.253811007274598 24.992298005263184 1.204887955311503 0.862297311068754 0.24820451972992885 0.24379600297664006 787.2239949707072 2579110.084106395 0.059110424822714905 0.15016544403839543 5.574282732412127e-06 5.253811007274598 -0.3425906442427491 KRPASPSHNGS(ph)SGGGYGASK ddPTM_PC-9_AZD4547_30min_R2 1 KRPASPSHNGSSGGGYGASK 20 2 K7ELX9;K7EQ79;K7ENM4;K7ENP7;Q6PI98;Q6PI98-3;Q6PI98-4 K7ELX9 INO80C INO80 complex subunit C 1 KRPAS(0.087)PS(0.344)HNGS(0.433)S(0.132)GGGY(0.003)GASK 41.615 0.037217 10542000.0 17363.0 21023.0 78690.0 128540.0 123850.0 97800.0 43546.0 113790.0 61428.0 89865.0 True False 22884.072827164455 27818.273622828146 77646.51918486746 98907.08892320334 106655.56530661356 91684.55053948458 47421.50964022005 96206.37013407059 64674.95867225252 86718.85370277708 0.2638880918052497 0.3207869158207899 0.8953822135494961 1.1405488506824664 1.229900543567702 1.0572620211716253 0.5468419797470343 1.1094054640506588 0.7458004333627553 1.0 16.40405806603541 -5.275168140083718 4.045696780292809 0.9789165335135056 0.2738091589353097 0.6736215949939325 0.1882927812955108 0.11964276128380566 4.663666869374303 0.052097709115516394 0.1318718609352228 5.306789484637986e-06 5.275168140083718 -0.705107374578196 KRPESPPS(ph)ILTPPVVPTADK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KRPESPPSILTPPVVPTADK 20 2 P55198;Q6P2C6 P55198 MLLT6 Protein AF-17 1 KRPES(0.009)PPS(0.897)ILT(0.094)PPVVPTADK;KRPES(0.002)PPS(0.892)ILT(0.106)PPVVPTADK 103.87 0.0012514000000000002 3655300.0 33137.0 44191.0 42508.0 42709.0 43488.0 39766.0 44811.0 40240.0 26242.9 26898.1 True False 38746.43961441693 48577.99043185535 43521.5519324877 40316.15319444619 34966.83858122007 37680.60095595787 40566.177676454725 39183.74263780431 26626.652765810886 31774.512604757547 1.2194188498304608 1.5288351086959504 1.3697000635021948 1.2688205070503493 1.100468133568933 1.185875025831742 1.2766892188420482 1.2331815479031893 0.8379877638728633 1.0 14.955582375178041 -7.053149895282928 0.3682683856413844 0.9580502295496208 1.431966878506589 0.5044266032224507 0.12790981265038484 1.3162666821530435 0.408425754338562 0.15372097609752094 0.22837598723580219 8.84810167862735e-08 7.053149895282928 0.4739166489569683 KRPESPPSILT(ph)PPVVPTADK ddPTM_PC-9_AZD4547_30min_R2 2 KRPESPPSILTPPVVPTADK 20 2 P55198;Q6P2C6 P55198 MLLT6 Protein AF-17 1 KRPES(0.1)PPS(0.147)ILT(0.741)PPVVPT(0.012)ADK;KRPES(0.036)PPS(0.39)ILT(0.573)PPVVPT(0.001)ADK 67.64399999999999 0.0025712 7365700.0 40104.0 48692.0 63287.0 75721.0 68030.0 76958.0 51928.0 72412.0 56071.0 66018.0 True False 52856.237784979756 64430.73677604278 62447.77302900877 58264.69332778797 58585.20878327764 72145.80409425012 56549.49140213447 61222.38926222265 59034.798588784746 63706.72991431526 0.8296805982047849 1.011364684118951 0.9802382434791462 0.914576739477183 0.9196078477434644 1.1324675460706477 0.8876533370680431 0.9610034818074319 0.9266650268846917 1.0 15.95915816492199 -4.750274859171277 24.72492591994423 0.9686336833269668 0.8296802512212385 0.290347030600392 0.06594625304539994 573.3999832465358 1269756.3876938217 0.01617222830218892 0.23955003682747383 1.77715431684087e-05 4.750274859171277 -0.1389534321057283 KRQS(ph)PEPSPVTLGR ddPTM_PC-9_Lapatinib_30min_R1 1 KRQSPEPSPVTLGR 14 2 Q9NRL2;Q9NRL2-2 Q9NRL2 BAZ1A Bromodomain adjacent to zinc finger domain protein 1A 1 KRQS(1)PEPSPVTLGR 79.88600000000001 0.003915 10700000.0 62121.0 44733.0 55397.0 42021.0 49086.0 44699.0 42789.0 39709.0 56036.0 37367.0 True False 61235.14314840384 44629.42348688731 50842.472498603944 45111.36451794669 46198.85798678907 42787.32796845827 45004.405051815054 41554.02510483154 49724.63559476036 43825.83616160226 1.397238444524069 1.0183359268337042 1.1601027373700006 1.0293326601140982 1.0541466411829907 0.9763037449116858 1.0268921027739657 0.9481627447245113 1.134596392215017 1.0 15.419493996254491 -2.656762744411435 1.4682802485999384 1.0320787270499967 199.99999999995615 0.7210130344221999 0.06557429207023119 384.8890477393196 1.9848148231337257 0.01769456702039186 256815.07020724958 0.0022041302531689336 2.656762744411435 198.96792127290615 KRS(ph)ESPPAELPSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KRSESPPAELPSLR 14 2 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 KRS(0.893)ES(0.107)PPAELPSLR 81.71300000000001 0.028386 14288000.0 59422.0 23904.0 42881.0 96625.0 79894.0 91102.0 90542.0 98044.0 76239.0 65638.0 True False 69480.97096200264 26277.03114396756 43903.44566709811 91211.41451247681 64239.34422387773 86324.45074409492 81965.2062926863 95470.44888620505 77353.85114498234 77537.64980987794 0.8960933318506525 0.3388938303959271 0.5662210006977154 1.1763500020458049 0.8284922793171109 1.1133230237924696 1.057102020678531 1.2312785997550644 0.9976295558951519 1.0 16.242609386768812 -5.7535665964401135 24.989986970855156 1.0601134375911472 0.5742516618454324 0.6218242046828026 0.16305059181209858 103.92659919404693 329882.7508734077 0.042875177761981104 0.07256558148421591 1.763735285567627e-06 5.7535665964401135 -0.48586177574571476 KRS(ph)ESPPAELPSLR ddPTM_PC-9_Lapatinib_30min_R1 1 KRSESPPAELPSLR 14 2 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 KRS(0.664)ES(0.336)PPAELPSLR 83.964 0.02101 27605000.0 136930.0 75950.0 102670.0 74148.0 55123.0 90097.0 58332.0 58666.0 80483.0 54197.0 True False 134977.35309011306 75774.14244135415 94228.86891766124 79601.09127047702 51880.77351598771 86243.76133636509 61352.14553933194 61391.836530762455 71418.15701643753 63564.8792370369 2.123458027612625 1.1920756139375055 1.482404592735505 1.2522810115573446 0.8161861414464657 1.3567832169515717 0.9651893667656702 0.9658137837693194 1.1235474348990002 1.0 15.955942249687475 -1.5228787453081074 0.7495512658395148 1.0626062682733446 173.44409997816285 0.7179667084376313 0.18816061203897583 199.56547144524268 0.862838254306041 0.06838383131835568 58083.40026932088 0.029999999998081728 1.5228787453081074 172.3814937098895 up KRS(ph)GNSDSIER ddPTM_PC-9_Lapatinib_30min_R1 1 KRSGNSDSIER 11 2 A0A5F9ZI51;A0A5F9ZGW5;C9J8U3;A0A0A0MRW7;Q7Z2E3-13;Q7Z2E3-4;Q7Z2E3-5;Q7Z2E3-9;Q7Z2E3-10;Q7Z2E3-11;Q7Z2E3-8;Q7Z2E3-7;Q7Z2E3 A0A5F9ZI51 APTX Aprataxin 1 KRS(0.89)GNS(0.108)DS(0.002)IER 46.3 0.042687 3411800.0 5729.4 4179.8 4420.4 3131.1 3982.2 4110.4 3355.0 3949.9 4805.1 4122.0 True False 5647.697705356717 4170.121929906145 4056.9717752374468 3361.3715390434077 3747.97482530643 3934.607773810395 3528.705483858925 4133.426773818883 4263.899038053806 4834.4822077802455 1.1682114986932302 0.8625788141685722 0.8391740006217143 0.6952909111205071 0.7752587897158306 0.813863326971881 0.7299034999405101 0.8549885171087944 0.8819763637131218 1.0 12.239145664277249 -4.711722403468067 2.660317137412585 0.8092991466314168 1.2825302293274483 0.6137761271097284 0.08075787097452028 0.3966501118936592 3.1083281761885875 0.020278431344578653 0.4550269233107995 1.942126868302917e-05 4.711722403468067 0.47323108269603154 KRS(ph)SITEPEGPNGPNIQK ddPTM_PC-9_AZD4547_30min_R2 1 KRSSITEPEGPNGPNIQK 18 2 Q13625-2;Q13625;Q13625-3 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 KRS(0.376)S(0.376)IT(0.249)EPEGPNGPNIQK 60.246 0.008532 7610500.0 29983.0 24077.0 34418.0 52185.0 47879.0 45042.0 34980.0 42534.0 32799.0 38503.0 True False 39516.970314857586 31859.419398603106 33961.59483167829 40154.55450021286 41231.82730169852 42225.51661962651 38093.15223476089 35961.34763408524 34532.688179514385 37155.021689401096 1.0635701048757633 0.8574727708392478 0.9140512718733315 1.0807302128871428 1.1097242156491698 1.136468630609677 1.0252490915818093 0.9678731433588057 0.9294218280422977 1.0 15.18126959103446 -4.466692109600125 23.0823041649646 1.0064150849413984 2.1959065066549153 0.04308168094270981 0.08463666011540898 878.611314304682 920811.5088354325 0.02303497805017106 82017.43416259356 3.414348839988694e-05 4.466692109600125 1.1894914217135168 KRS(ph)SITEPEGPNGPNIQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KRSSITEPEGPNGPNIQK 18 2 Q13625-2;Q13625;Q13625-3 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 KRS(0.333)S(0.333)IT(0.333)EPEGPNGPNIQK;KRS(0.48)S(0.48)IT(0.039)EPEGPNGPNIQK 79.317 0.011479000000000001 18896400.0 68695.0 45301.3 51196.0 79835.0 97493.0 104311.0 73976.0 102131.0 97864.0 66230.0 True False 80323.70671190438 49798.51367813826 52416.70680191123 75362.1037785621 78389.94650935642 98840.7475309793 66968.45774014012 99450.16946673956 99295.07585950191 78236.97472360841 1.0266719411846876 0.6365086821680402 0.6699735896880764 0.9632543186236111 1.0019552364631739 1.2633508373778364 0.8559694182542572 1.2711402737397766 1.2691579168326292 1.0 16.255562964619365 -6.143814163414581 2.1349918856777097 1.127577230437661 0.7681351293313923 0.4577548407643849 0.16116204924185246 0.2740645690135492 2.456243645507433 0.05269599544697031 0.07404504326107686 7.181015044397757e-07 6.143814163414581 -0.35944210110626873 KRS(ph)SITEPEGPNGPNIQK ddPTM_PC-9_Lapatinib_30min_R1 1 KRSSITEPEGPNGPNIQK 18 2 Q13625-2;Q13625;Q13625-3 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 KRS(0.333)S(0.333)IT(0.333)EPEGPNGPNIQK 90.725 0.006254399999999999 0.0 11429.0 9070.7 6948.8 6707.8 5165.4 5312.7 4430.9 5500.5 7932.0 4643.4 True False 11266.020364178084 9049.697351452145 6377.4964871436905 7201.113988564833 4861.581327567133 5085.488205508579 4660.310321439793 5756.073310562491 7038.614632337057 5446.005503058419 2.068675905276116 1.6617128547464617 1.171041138970968 1.322274460523546 0.8926875532602602 0.933801517947902 0.8557300059323503 1.0569349052860746 1.2924361953700276 1.0 12.410982724853396 -4.792594256145982 0.9680632686445156 1.0093874523753643 2.6535160736885093 0.8550707067880838 0.13883058760839895 0.7207281316674696 0.5408834123569056 0.049088187487576006 1.2439283144533329 1.6121510997044192e-05 4.792594256145982 1.644128621313145 up KRS(ph)SSEDAESLAPR ddPTM_PC-9_Lapatinib_30min_R1 1 KRSSSEDAESLAPR 14 2 H0YA82;Q4G0J3;Q4G0J3-3 H0YA82 LARP7 La-related protein 7 1 KRS(0.333)S(0.333)S(0.333)EDAESLAPR 65.043 0.012737 8670200.0 28482.0 19295.0 33375.0 25658.0 28271.0 39299.0 32077.0 29877.0 39999.0 25876.0 True False 28075.84145704088 19250.323612981265 30631.036331225652 27544.97491257887 26608.155362924525 37618.27338044344 33737.79010603361 31265.19449135088 35493.89141185702 30348.63212239729 0.9251106060994726 0.6343061372698419 1.0093053356635455 0.907618333554173 0.8767497413264866 1.2395376908167521 1.111674159479996 1.0302011097322956 1.169538424951368 1.0 14.889343872152098 -6.736542676357497 22.018221419346624 1.1121703943023638 0.8672494207906416 0.5479215526869476 0.10877739262266838 45.46617534473872 40208.81826441445 0.03573203221596381 0.03570354716901504 1.8342449144523852e-07 6.736542676357497 -0.24492097351172215 KRS(ph)VQEGENPDDGVR ddPTM_PC-9_Lapatinib_30min_R1 1 KRSVQEGENPDDGVR 15 2 H7C5M1;Q5TCT4;A2A2V2;P42696-2;P42696 H7C5M1 RBM34 RNA-binding protein 34 1 KRS(1)VQEGENPDDGVR 113.33 0.00063425 8639800.0 21980.0 13812.0 18840.0 20118.0 28052.0 38709.0 33037.0 35046.0 42100.0 35753.0 True False 21666.56116936166 13780.019162606746 17291.047924503106 21597.544831680625 26402.036512353967 37053.50630508624 34747.49420871753 36674.36510171311 37358.25466734618 41932.85841212205 0.5166964998288368 0.3286210309627542 0.4123508050551729 0.5150506225790026 0.6296264436082804 0.883638933957689 0.8286459717869518 0.8745973084227238 0.8909064652875313 1.0 15.355793556417206 -6.489826303641838 1.4356810861588476 0.8983979827832087 0.4092693766602029 0.9232956353999464 0.06187889625131582 0.09887731185337742 0.41696327327479243 0.024521751344863577 0.027972768329333954 3.237231043059943e-07 6.489826303641838 -0.4891286061230058 KRSS(ph)ITEPEGPNGPNIQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KRSSITEPEGPNGPNIQK 18 2 Q13625-2;Q13625;Q13625-3 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 KRS(0.198)S(0.604)IT(0.198)EPEGPNGPNIQK 68.458 0.033647 8153500.0 6191.3 2557.2 5722.3 8904.1 7589.7 10731.0 7678.2 10766.0 8408.3 7272.6 True False 7239.364806251004 2811.061916053959 5858.741333943597 8405.232144481693 6102.552768117321 10168.247469154148 6950.865310645922 10483.403907519905 8531.255480559217 8591.064810130072 0.8426621107216856 0.3272076253853099 0.6819575295294383 0.9783690765050154 0.7103371820593827 1.1835840718096267 0.8090807675493119 1.2202682832934166 0.9930381936473892 1.0 13.068621240366818 -5.979242726761616 1.0899410353809322 1.0316317216230224 0.5636307499399665 0.44492232875164583 0.18618776001836243 0.4515516822238546 1.087809782391339 0.07096823075176402 0.1488093050797613 1.0489560043056467e-06 5.979242726761616 -0.4680009716830559 KRSS(ph)ITEPEGPNGPNIQK ddPTM_PC-9_Lapatinib_30min_R1 1 KRSSITEPEGPNGPNIQK 18 2 Q13625-2;Q13625;Q13625-3 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 KRS(0.375)S(0.613)IT(0.012)EPEGPNGPNIQK 88.57 0.004296100000000001 4371900.0 17916.0 7515.2 9340.7 8082.1 8801.1 8219.3 6701.5 5752.2 9205.7 5718.7 True False 17660.514554607988 7497.799016132511 8572.743702144702 8676.484595095244 8283.436601628355 7867.77969912411 7048.470879308664 6019.468211438516 8168.857125681443 6707.16967531123 2.633080033686265 1.1178782376315228 1.278146240089998 1.2936134040313558 1.2350122335683988 1.1730402062266339 1.0508860250328462 0.8974677103511918 1.2179290999228205 1.0 12.711488383901846 -4.760746350517337 24.99800958194325 1.1475025743093907 2.6330817450810464 0.9320408958449615 0.12090204386779042 4.250116127828481 153195.84725193307 0.032665820876878617 0.18974261260819883 1.7348169209125306e-05 4.760746350517337 1.4855791707716557 KRYLTIGLS(ph)SVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KRYLTIGLSSVK 12 2 F8VWY2;Q9UBM8;Q9UBM8-2 F8VWY2 MGAT4C Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C 1 KRYLT(0.011)IGLS(0.494)S(0.494)VK 47.559 0.039585 12446000.0 18152.0 0.0 385030.0 75217.0 234710.0 223800.0 75945.0 89113.0 180120.0 56620.0 True False 21224.77508165784 0.0 394210.57543440716 71002.8353468041 188720.26037983276 212063.5340226166 68750.93980581434 86773.8781730283 182753.91424643833 66884.7577963265 0.3173335118636486 0.0 5.893877595173983 1.0615697460252114 2.8215735034058507 3.1705808768625565 1.0279014542471787 1.2973640188287285 2.732370128377376 1.0 16.029389855631905 -7.284515364627177 24.294195094538978 1.5391893772889669 2.25326508268701 0.04132024889948627 1.6339515361387267 2322.434836630306 2445026.0506804446 0.6974151220077738 0.4705907905131886 5.1937929839339584e-08 7.284515364627177 0.7140757053980431 KS(ph)APSTGGVK ddPTM_PC-9_AZD4547_30min_R2 1 KSAPSTGGVK 10 1 K7EMV3;A0A590UJJ6;B4DEB1;K7EK07;K7ES00;P84243;K7EP01 K7EMV3 H3F3B;H3F3A Histone H3;Histone H3.3 1 KS(1)APSTGGVK 54.199 0.043711 5471100.0 16955.0 19786.0 34105.0 51445.0 41291.0 37175.0 22018.0 32647.0 33378.0 34746.0 True False 22346.337314091666 26181.437563681582 33652.74541618889 39585.15006732685 35558.457384540896 34850.44137326529 23977.559345482136 27602.156303427397 35142.292937462444 33529.55311585928 0.6664668997190416 0.7808466004069085 1.0036741408364116 1.1806047617319215 1.0605109248450424 1.0393947468623206 0.7151171762602733 0.823218735067833 1.048099055064362 1.0 15.033145634472675 -5.098000174735238 3.427122263821175 0.9792628441977168 0.6831180063725966 0.42809270505105246 0.12318203459304443 0.26314382938419595 5.607090816233029 0.03653912098498525 0.12943789989675406 7.979943662006613e-06 5.098000174735238 -0.29614483782512024 KS(ph)ASPEVSEGHENQHGQESEAK ddPTM_PC-9_AZD4547_30min_R2 2 KSASPEVSEGHENQHGQESEAK 22 1 O60930 O60930 RNASEH1 Ribonuclease H1 1 KS(0.498)AS(0.498)PEVS(0.005)EGHENQHGQESEAK;KS(0.446)AS(0.446)PEVS(0.109)EGHENQHGQESEAK 62.193000000000005 0.0019917999999999997 7815900.0 24535.6 20169.8 43378.0 73017.0 56018.0 50966.0 35139.0 51001.0 46713.0 52460.0 True False 32337.41042781641 26689.293408063517 42802.779377318315 56184.05875140447 48240.86764106491 47779.087963142956 38266.30292673707 43119.96733638926 49182.153813520425 50623.391367581266 0.6387839604227894 0.5272126715942441 0.8455138666337713 1.1098438337219778 0.9529363074627573 0.9438144437265068 0.7559016077939505 0.851779506894176 0.9715302054025603 1.0 15.627516539414112 -5.374424370503183 4.569475644996238 0.9305040128046352 0.5851946281676752 0.7014127673608216 0.09158555869496082 0.1246164696812897 4.102007191853429 0.026153052808812024 0.05730154730675154 4.2225580569024775e-06 5.374424370503183 -0.34530938463696004 KS(ph)ASPEVSEGHENQHGQESEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KSASPEVSEGHENQHGQESEAK 22 1 O60930 O60930 RNASEH1 Ribonuclease H1 1 KS(0.474)AS(0.474)PEVS(0.052)EGHENQHGQESEAK;KS(0.49)AS(0.49)PEVS(0.02)EGHENQHGQESEAK 46.656000000000006 0.013606 9705900.0 28821.0 35991.0 60632.0 73230.0 81316.0 86987.0 70512.0 75553.0 71985.0 52546.0 True False 33699.82605930261 39563.94862376739 62077.69682814045 69127.16051486331 65382.71353179017 82425.24858813832 63832.59289732824 73569.81380502053 73037.64444275975 62072.1738460929 0.5429135790033851 0.6373862259418472 1.000088976778246 1.1136577991655836 1.053333715907964 1.3278936998808932 1.0283608409719995 1.1852301803934864 1.1766567838248356 1.0 15.921659051359626 -5.283656308055541 1.916998620988809 1.1385994872086318 0.5216969803294202 0.8514757752676887 0.08868845526935004 0.12814455576732184 0.843711019441153 0.024214911538827773 0.0960684950864744 5.204076738132444e-06 5.283656308055541 -0.6169025068792116 KS(ph)DASDMNSDTSPSCR ddPTM_PC-9_AZD4547_30min_R2 1 KSDASDMNSDTSPSCR 16 1 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 KS(0.99)DAS(0.009)DMNSDTSPSCR 52.568999999999996 0.030044 5869400.0 21487.0 17143.0 20073.0 21336.0 20532.0 23231.0 16778.0 21160.0 16294.0 14824.0 True False 28319.419042635647 22684.139500363555 19806.818904534794 16417.314837913986 17681.48620811783 21778.36189757436 18271.20949670721 17890.20820842722 17155.26757513972 14305.016272074436 1.979684503954005 1.5857472000676043 1.3846065273760444 1.1476613885412403 1.2360339807955882 1.5224283204828666 1.2772589103848409 1.2506248065828225 1.1992483789500754 1.0 13.804233518289031 -4.829121958140394 1.4603575720948136 1.2575429097509185 2.2251029328966547 0.7713409249637015 0.12621104374344339 0.5136559052166348 1.0846272745963164 0.036931709540884414 0.7119353936360717 1.482101824355374e-05 4.829121958140394 0.9675600231457362 KS(ph)DASDMNSDTSPSCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSDASDMNSDTSPSCR 16 1 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 KS(0.97)DAS(0.029)DMNS(0.001)DTSPSCR 48.623000000000005 0.039248000000000005 4884000.0 16584.0 15437.0 17146.0 19041.0 20019.0 14350.0 15884.0 13508.0 14278.0 11447.0 True False 19391.343651069514 16969.483340421146 17554.825666567103 17974.19450175491 16096.42065759393 13597.460738268763 14379.35252979864 13153.429312909057 14486.7887386778 13522.250485597857 1.434032276781343 1.254930409586395 1.2982177548969545 1.329230997525056 1.1903655145818919 1.0055619626889039 1.0633845708681153 0.9727248675742532 1.0713297135049558 1.0 13.723047656481665 -6.548658355304868 2.6057557614675053 1.0218650278980517 1.322088740650313 0.8883710090456887 0.05115819691844832 0.08595006422692385 1.181741829148694 0.01745090150174192 0.018366341817770197 2.827103086203888e-07 6.548658355304868 0.30022371275226134 KS(ph)FTPDHVVYAR ddPTM_PC-9_AZD4547_30min_R2 1 KSFTPDHVVYAR 12 1 Q6NZI2;Q6NZI2-3;Q6NZI2-2 Q6NZI2 PTRF Polymerase I and transcript release factor 1 KS(0.569)FT(0.43)PDHVVY(0.001)AR 56.551 0.034884 9682200.0 35394.0 27969.0 48068.0 70399.0 49546.0 52594.0 32074.0 58338.0 41274.0 49897.0 True False 46648.555759065755 37009.432286394935 47430.58691292673 54169.59820370771 42667.39312621304 49305.28886578388 34928.52386442883 49323.202573876544 43455.65937745896 48150.12121746482 0.9688149184169775 0.768625942170443 0.9850564383568551 1.1250147836400366 0.8861326212141891 1.0239909603363586 0.7254088459440825 1.0243629990278453 0.9025036340240177 1.0 15.555251809593578 -13.953136808677607 0.004985726558771801 1.9060345381548764 0.04639119670580619 0.010192256792412868 0.11541536655016112 444100.83736456174 183.55291774425774 36669.77448455859 31943.468218016995 1.1139435709170315e-14 13.953136808677607 -1.8596433414490703 KS(ph)FTPDHVVYAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSFTPDHVVYAR 12 1 Q6NZI2;Q6NZI2-3;Q6NZI2-2 Q6NZI2 PTRF Polymerase I and transcript release factor 1 KS(0.97)FT(0.029)PDHVVYAR 51.727 0.045821 13163000.0 47085.0 34262.0 53909.0 48560.0 54879.0 61752.0 53975.0 56723.0 45450.0 34557.0 True False 55055.56052885961 37663.30493033035 55194.39501102098 45839.34063364417 44125.85390219781 58513.61641181691 48862.09725484018 55234.08135298639 46114.62026704763 40821.91054693851 1.348676722652526 0.9226247479775284 1.3520777021829113 1.1229102219734777 1.0809355395421854 1.4333875026387077 1.1969576288855164 1.3530498845583487 1.129653650434204 1.0 15.317056084509291 -5.3280349328525665 24.99999619288903 1.221219726592495 1.1356236301637952 0.027379148934864928 0.16047871702023261 569.2869108582244 213708.60802044102 0.039602956916920215 0.08244015932386642 4.698563137859109e-06 5.3280349328525665 -0.0855960964286997 KS(ph)GSQDFPQCNTIENTGTK ddPTM_PC-9_AZD4547_30min_R2 2 KSGSQDFPQCNTIENTGTK 19 1 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 KS(0.598)GS(0.401)QDFPQCNT(0.001)IENTGTK;KS(0.596)GS(0.404)QDFPQCNTIENTGTK 87.46799999999999 0.00053818 14017500.0 111369.0 105393.0 106536.0 112925.0 150359.0 121466.0 107476.0 117248.0 110624.0 118557.0 True False 146782.02538089477 139459.22617755455 105123.26303061422 86891.88592385818 129484.24823526156 113870.71181829312 117041.15579139984 99130.01569100565 116471.35879662786 114406.35551594215 1.2829883857321298 1.218981459103654 0.9188585944944784 0.7595022630692058 1.1317924397759385 0.9953180599518844 1.0230301914922073 0.8664729790924265 1.0180497252217597 1.0 16.803807673551773 -5.196513813273362 5.0846667633094444 0.9613203414132901 1.262097102581506 0.5911083382766307 0.0956849747608938 0.14610237903121084 7.504788324485643 0.02513196777721308 0.06972341684687425 6.3604257439446256e-06 5.196513813273362 0.30077676116821583 KS(ph)GSQDFPQCNTIENTGTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSGSQDFPQCNTIENTGTK 19 1 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 KS(0.489)GS(0.489)QDFPQCNT(0.012)IENT(0.007)GT(0.003)K 52.731 0.035039999999999995 4763500.0 33587.0 40870.0 34620.0 42769.0 45136.0 41034.0 33534.0 38405.0 37086.0 26339.0 True False 39272.6157265118 44927.303499579706 35445.472097081154 40372.79158896884 36291.924811487064 38882.104803771465 30357.416754864495 37396.909443461074 37628.31259018108 31114.05220059074 1.2622147534279113 1.4439553938502008 1.139211050639305 1.2975742063003388 1.166415887506868 1.2496638031298681 0.9756818738733144 1.2019298933602434 1.20936714856661 1.0 14.925278678921643 -1.522878746066186 0.12119291037576001 0.9600382578877124 2.19769334481934 0.4194814856037118 0.09943359908646843 88.39002862481514 0.7378393377938127 0.6523234699969723 18.48639957287655 0.02999999994571552 1.522878746066186 1.2376550869316274 KS(ph)GSQDFPQCNTIENTGTK ddPTM_PC-9_Lapatinib_30min_R1 1 KSGSQDFPQCNTIENTGTK 19 1 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 KS(0.499)GS(0.499)QDFPQCNT(0.001)IENTGTK 84.12700000000001 0.00062932 7721800.0 32884.0 33108.0 36496.0 36294.0 34177.0 34381.0 27383.0 29328.0 36699.0 59901.0 True False 32415.068129812957 33031.34046014946 33495.43975863405 38963.18183323478 32166.7760545673 32910.60477602546 28800.757753951988 30690.685947127848 32565.57216239757 70254.8080369347 0.4613928788015697 0.47016483829525324 0.47677078188050365 0.5545980826358655 0.45785871392113725 0.46844629848997005 0.4099471418213927 0.43684819309438566 0.46353513833924415 1.0 16.100309342159576 -10.806536681471899 3.5214307705595598 1.0015994752024946 0.46686236003613146 0.9549772409700018 0.03474390976765679 21869582.377033994 33548056.180968717 372339.27571850305 0.009413274622572243 1.5612171685477935e-11 10.806536681471899 -0.5347371151663631 KS(ph)LSDSESDDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSLSDSESDDSK 12 1 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 KS(0.691)LS(0.298)DS(0.01)ES(0.002)DDSK 65.477 0.019041 35437000.0 170760.0 183310.0 174720.0 201650.0 217920.0 156960.0 202390.0 230580.0 169490.0 151660.0 True False 199666.29533626584 201507.80534641433 178885.98742929025 190352.2042581206 175220.1403518095 148728.74128771198 183218.15402329067 224527.51931970505 171968.47060642243 179154.7574601009 1.1144906122893947 1.1247694909318366 0.9984997884810818 1.0625015319535316 0.9780378865508628 0.8301690861926174 1.0226809302794804 1.2532601562071775 0.9598878257236406 1.0 17.450846829305377 -5.25693867207342 24.17150226933429 1.0164914705147028 1.1196300710829725 0.15523944696480563 0.09912710338034696 489.5189113349908 2628965.749220353 0.0272696646032452 0.06713685746679376 5.534282548346272e-06 5.25693867207342 0.10313860056826973 KS(ph)LSDSESDDSKSK ddPTM_PC-9_Lapatinib_30min_R1 1 KSLSDSESDDSKSK 14 2 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 KS(0.498)LS(0.498)DS(0.003)ESDDSKSK 82.755 0.024939 15103000.0 202350.0 39906.0 39824.0 46455.0 36073.0 34812.0 25303.0 19620.0 44451.0 24806.0 True False 199464.45189355485 39813.60010881732 36549.82444508553 49871.45566933712 33951.25706224669 33323.171910735546 26613.065531470147 20531.61682633142 39444.46029021865 29093.684048082683 6.855936551861326 1.3684619673128366 1.2562803797786557 1.7141677756215175 1.1669631458888454 1.1453747781017645 0.9147368716690243 0.7057070116111502 1.3557739963433095 1.0 14.828418371806723 -4.761142626706133 5.9988358614986375 1.1673281820051704 7.06780293553281 0.9781656703507375 0.2545360100511298 0.018784716780836572 2.6018036941635785 0.06956989387338407 0.4561031695378668 1.7332346924502722e-05 4.761142626706133 5.900474753527639 up KS(ph)MSEDGGLQESNPCADDFVSASTADVSHTNLGTIR ddPTM_PC-9_Lapatinib_30min_R1 1 KSMSEDGGLQESNPCADDFVSASTADVSHTNLGTIR 36 1 A0A1W2PRP5;H7C0I1;B8ZZW5;Q8NBF6-2;Q8NBF6 A0A1W2PRP5 AVL9 Late secretory pathway protein AVL9 homolog 1 KS(0.493)MS(0.493)EDGGLQES(0.013)NPCADDFVSASTADVSHTNLGTIR 85.242 1.838e-12 7115600.0 21623.0 20873.0 28862.0 24401.0 34353.0 31954.0 31264.0 28374.0 43487.0 23111.0 True False 21314.652054827453 20824.669850933296 26489.07777054186 26195.5309393498 32332.424080596607 30587.40190841216 32882.696944073126 29692.359624379602 38589.03612158871 27105.705556528195 0.7863529695021714 0.7682762511938317 0.9772509966693036 0.9664212903338653 1.1928272449196438 1.128448836892402 1.2131282425206449 1.0954283983664255 1.4236499411945707 1.0 14.726308940048336 -5.711497468791606 0.9580565493624621 1.1922289366130894 0.7356088250337225 0.6729402293478092 0.10824173973174181 0.39042196726226724 0.6515922850170625 0.040719313944241387 0.13694605685659303 1.943133017001723e-06 5.711497468791606 -0.4566201115793669 KS(ph)MSLDMGQPSQANTK ddPTM_PC-9_Lapatinib_30min_R1 1 KSMSLDMGQPSQANTK 16 1 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 KS(0.5)MS(0.5)LDMGQPSQANTK 54.271 0.037817 0.0 9352.0 12404.0 9907.1 7358.5 8206.9 6160.6 7461.1 6619.4 7668.0 6045.9 True False 9218.638765053238 12375.279300099482 9092.576480511922 7899.668637236404 7724.186277386203 5897.125499060021 7847.399250557324 6926.9614893077605 6804.349092380302 7090.925759344634 1.3000613852013103 1.7452275937018478 1.2822834125049825 1.114053214677362 1.0893057605640617 0.8316439487874503 1.1066819082424868 0.9768768880677116 0.9595854368399398 1.0 12.791758276192825 -5.685243294341307 2.118366401803148 0.996090315022689 1.525973465266171 0.7261224370493662 0.12715558893209367 0.1470317490336217 1.337638281899251 0.03589999544217677 0.07476844496010941 2.064223441642275e-06 5.685243294341307 0.529883150243482 KS(ph)PEIHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSPEIHR 7 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 KS(1)PEIHR 54.608000000000004 0.045205 5378000.0 7572.4 17004.0 9920.0 8430.1 16252.0 10753.0 7439.1 8933.2 11091.0 11394.0 True False 8854.257758282612 18692.044744478913 10156.530421809506 7957.788827752953 13067.537265958175 10189.093750425363 6734.414593580018 8698.712965507792 11253.184892889452 13459.642005145628 0.6578375379447406 1.3887475415269541 0.7545914236000228 0.5912333199286196 0.9708681152858634 0.7570107545601932 0.5003412862693858 0.646281153851066 0.8360686627911318 1.0 13.716352417709452 -5.476062226957938 24.988723625105173 0.7356050527809374 1.0353870185848117 0.18387119294479148 0.22076748021655127 548.0231814420821 292510.94146833755 0.05492897860647706 0.11433803507911795 3.3414715903341094e-06 5.476062226957938 0.2997819658038744 KS(ph)PGVEIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSPGVEIK 8 1 Q9Y597-3;Q9Y597-2;Q9Y597 Q9Y597-3 KCTD3 BTB/POZ domain-containing protein KCTD3 1 KS(1)PGVEIK 64.265 0.025206 6747500.0 34317.0 42185.0 46889.0 57999.0 62018.0 54314.0 66201.0 59331.0 57350.0 44034.0 True False 40126.19030835458 46372.84800904749 48007.01158752274 54749.50406529506 49866.0180999381 51465.67822566756 59929.962026265464 57773.624116390856 58188.63525445945 52017.01562704779 0.7714050839835144 0.8914938208207115 0.9229097634459458 1.0525306653084194 0.9586481942268288 0.9894008259656183 1.1521222681430248 1.1106677962960594 1.1186461690086378 1.0 15.666696009442294 -4.133736026302172 0.4380416494676535 1.0947492762657838 0.3258093041128218 0.7435785406826974 0.056369036625191334 4.5288150479218015 0.4403326144128624 0.041201429344738576 2.0330743289622024 7.349604574828189e-05 4.133736026302172 -0.768939972152962 KS(ph)PLGGGGGSGASSQAACLK ddPTM_PC-9_AZD4547_30min_R2 2 KSPLGGGGGSGASSQAACLK 20 1 J3QQY0;J3KSZ8;Q68DK7;Q68DK7-2 J3QQY0 MSL1 Male-specific lethal 1 homolog 1 KS(0.999)PLGGGGGS(0.001)GASSQAACLK;KS(1)PLGGGGGSGASSQAACLK 102.73 9.798e-05 27491000.0 93512.0 86393.0 124596.0 180328.0 155486.0 153121.0 123501.0 145746.0 118572.0 137814.0 True False 123246.87082956868 114317.84774280516 122943.77563041996 138756.16563982717 133899.45278372345 143546.31966417632 134492.349746861 123224.30460989743 124839.47385046445 132989.1738073166 0.9267436386072808 0.8596026614048773 0.9244645418171326 1.0433643707033338 1.0068447599932135 1.0793834983301391 1.011302994796571 0.9265739539703649 0.938719072210645 1.0 17.02094928008644 -5.5979655240105926 5.59164130469422 1.0014235942088923 0.8927596374634607 0.5081109750333175 0.04451109246595726 0.1675404509040208 9.0818592752093 0.013447798550141037 0.023773566509477748 2.5236811041754922e-06 5.5979655240105926 -0.10866395674543161 KS(ph)PLGGGGGSGASSQAACLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSPLGGGGGSGASSQAACLK 20 1 J3QQY0;J3KSZ8;Q68DK7;Q68DK7-2 J3QQY0 MSL1 Male-specific lethal 1 homolog 1 KS(1)PLGGGGGSGASSQAACLK 102.67 0.00078358 0.0 5053.0 6347.8 4994.0 5235.9 6295.6 6591.2 7206.4 7459.0 6908.1 4657.1 True False 5908.373098700808 6977.9676328512915 5113.075899850468 4942.549498016834 5062.022373342741 6245.545868855547 6523.757622182129 7263.209153463774 7009.117893658788 5501.395364416682 1.0739771834826632 1.268399591490035 0.9294143687476298 0.8984174324182383 0.9201342637695467 1.1352657744346226 1.1858368995579085 1.320248531934752 1.2740618387462452 1.0 12.425581872391176 -7.029135216118246 3.6124958919468426 1.2190910519538445 1.0202420615517296 0.29502585952922766 0.1269303223337184 0.2944583081986421 8.086049419389205 0.053152488791338826 0.04253554396895732 9.351144840871279e-08 7.029135216118246 -0.1988489904021149 KS(ph)PLGGGGGSGASSQAACLK ddPTM_PC-9_Lapatinib_30min_R1 2 KSPLGGGGGSGASSQAACLK 20 1 J3QQY0;J3KSZ8;Q68DK7;Q68DK7-2 J3QQY0 MSL1 Male-specific lethal 1 homolog 1 KS(1)PLGGGGGSGASSQAACLK;KS(1)PLGGGGGSGASSQAACLK 104.26 7.367e-05 23221000.0 82343.0 88947.0 91324.0 91534.0 93559.0 101453.0 85250.0 81255.0 92287.0 75245.0 True False 81168.77372014317 88741.04868638738 83815.6932408346 98265.715708473 88056.04356407115 97114.09168849398 89663.82786854634 85030.40393596128 81892.66623480715 88250.99799233973 0.9197490744205374 1.0055529195725377 0.949742157568687 1.1134799372694069 0.997790909647441 1.1004305208755099 1.0160092226529749 0.9635064290529836 0.9279517297007283 1.0 16.42932497283931 -10.736214150843345 4.745328642693184 0.9999992975396939 1.0037985529094766 0.0 0.06238478812246358 4.7393453076909186e-07 7.852955077342553e-08 0.0617367792113882 0.014970599839519615 1.835632968539106e-11 10.736214150843345 0.0037992553697827613 KS(ph)PLSSILFSALDSDTR ddPTM_PC-9_AZD4547_30min_R2 1 KSPLSSILFSALDSDTR 17 1 A0A1W2PRB5;A0A0J9YVS1;A0A3B3IT55;A0A0G2JNB1;A0A0G2JNT7;Q7Z3B3;A0A0G2JQF5;A0A0G2JQF4;A0A1W2PRR3;I3L233;A0A1W2PPV8 A0A1W2PRB5 KANSL1 KAT8 regulatory NSL complex subunit 1 1 KS(0.994)PLS(0.005)S(0.001)ILFSALDSDTR 70.12100000000001 0.006945300000000001 947290.0 2144.8 2477.6 2518.6 4034.3 2689.2 2480.1 3300.0 3839.0 3038.0 3360.4 True False 2826.8017853886054 3278.43574789131 2485.2017183759954 3104.254464313669 2315.850998970896 2325.018954938407 3593.6936070529136 3245.770761443861 3198.5824778000783 3242.7534188261543 0.8717288736717701 1.0110037133437275 0.766386276535209 0.9572897051905289 0.7141619173156902 0.7169891307307732 1.1082229028545119 1.0009304878379557 0.9863785692832403 1.0 11.66300360911515 -7.269789791658167 24.966930981236583 1.0239605296300618 0.8437054743464915 0.4746373860308619 0.09492590610398925 608.3854569343241 1819006.479553714 0.040977691337860826 0.028147716061723248 5.372917948110524e-08 7.269789791658167 -0.18025505528357033 KS(ph)PLSSILFSALDSDTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSPLSSILFSALDSDTR 17 1 A0A1W2PRB5;A0A0J9YVS1;A0A3B3IT55;A0A0G2JNB1;A0A0G2JNT7;Q7Z3B3;A0A0G2JQF5;A0A0G2JQF4;A0A1W2PRR3;I3L233;A0A1W2PPV8 A0A1W2PRB5 KANSL1 KAT8 regulatory NSL complex subunit 1 1 KS(0.993)PLS(0.006)S(0.001)ILFSALDSDTR 82.24799999999999 0.0020981 1085400.0 2581.4 4554.9 3213.1 4178.7 5054.8 5136.7 3788.3 2698.1 3208.9 2547.3 True False 3018.380035025981 5007.0803697145975 3289.7124897496083 3944.580986528188 4064.3482261854138 4867.322409356458 3429.4447990831127 2627.2777338732544 3255.824091857629 3009.1053255842935 1.0030822149569945 1.663976440818783 1.0932526893557066 1.3108816607349059 1.3506832717449724 1.617531419712384 1.1396891859932485 0.8731092632535561 1.0819907379697415 1.0 11.555118889850705 -7.516757881880778 21.582688008583514 0.9878093643968946 1.3455932902240872 0.4042763645123395 0.19486237543232718 44.011279844525106 155199.50049730163 0.08400604341533748 0.050879579932167 3.042580784341767e-08 7.516757881880778 0.35778392582719265 KS(ph)PLSSILFSALDSDTR ddPTM_PC-9_Lapatinib_30min_R1 1 KSPLSSILFSALDSDTR 17 1 A0A1W2PRB5;A0A0J9YVS1;A0A3B3IT55;A0A0G2JNB1;A0A0G2JNT7;Q7Z3B3;A0A0G2JQF5;A0A0G2JQF4;A0A1W2PRR3;I3L233;A0A1W2PPV8 A0A1W2PRB5 KANSL1 KAT8 regulatory NSL complex subunit 1 1 KS(0.926)PLS(0.065)S(0.008)ILFSALDSDTR 70.942 0.0064363 1027300.0 743.59 598.19 2126.0 753.32 1181.1 2074.4 965.26 1155.7 801.28 996.33 True False 732.986270242295 596.804927807684 1951.2084865973256 808.7216658018523 1111.630020131943 1985.6827476625822 1015.2364397465469 1209.398041090277 711.0314085475329 1168.5443129737243 0.6272644195896889 0.5107251142996265 1.6697770593156789 0.692076164183974 0.9512947072610834 1.6992789452797001 0.8688043991784634 1.0349612142757236 0.6084762046704865 1.0 10.190496729005556 KS(ph)PSSDSWTCADTSTER ddPTM_PC-9_AZD4547_30min_R2 3 KSPSSDSWTCADTSTER 17 1 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHH7;H0YIQ0 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 KS(0.929)PS(0.065)S(0.006)DSWTCADTSTER;KS(0.802)PS(0.126)S(0.071)DS(0.001)WTCADTSTER;KS(0.721)PS(0.243)S(0.025)DS(0.007)WT(0.004)CADTSTER 98.508 0.00061841 27909200.0 30888.9 30934.4 41933.6 64303.0 49546.4 41513.1 37400.2 47350.2 41635.4 42110.0 True False 40710.92767096701 40933.3398448373 41377.53306507248 49478.93682144654 42667.73759311752 38917.27929448556 40728.745346212236 40033.31458935118 43836.162243646264 40635.74171728648 1.0018502419422688 1.007323555938053 1.0182546525899991 1.2176211071938712 1.0500051380867652 0.9577105683278353 1.0022887149340796 0.9851749444583406 1.078758757465926 1.0 15.310461607318222 -6.544503084816673 23.635352046191827 1.003720966990415 1.0642720616871233 0.15344888085532393 0.06393795919706197 247.77077346595044 270809.72235787177 0.02241332896025977 0.022415944501872658 2.854282239596875e-07 6.544503084816673 0.060551094696708274 KS(ph)PSSDSWTCADTSTER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KSPSSDSWTCADTSTER 17 1 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHH7;H0YIQ0 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 KS(0.995)PS(0.004)S(0.001)DSWTCADTSTER;KS(0.988)PS(0.01)S(0.002)DSWTCADTSTER 88.76799999999999 0.0012238 16756400.0 34904.0 35637.0 36907.0 35600.0 35091.0 33281.0 33425.0 29115.5 34179.0 24269.5 True False 40812.557814576096 39174.805843271926 37787.00285057693 33605.44741675723 28215.17045285121 31535.68577214791 30258.742023956132 28351.248975422226 34678.80321468474 28669.368232743695 1.4235597200207395 1.3664342208465488 1.3180270504677483 1.1721725830838494 0.9841573844179189 1.0999783991099794 1.0554380472673686 0.988903862312594 1.209611698909974 1.0 14.807222492794434 -5.800676993098693 2.1184414918667867 1.0574023119546647 1.3907893908130373 0.8260413076636467 0.06460861702788331 0.11699067079210732 1.0721493867562384 0.01891792086508057 0.035193697150277745 1.5824245313388494e-06 5.800676993098693 0.3333870788583726 KS(ph)PSSDSWTCADTSTER ddPTM_PC-9_Lapatinib_30min_R1 3 KSPSSDSWTCADTSTER 17 1 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHH7;H0YIQ0 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 KS(0.981)PS(0.015)S(0.004)DSWTCADTSTER;KS(0.983)PS(0.015)S(0.002)DSWTCADTSTER;KS(0.442)PS(0.442)S(0.115)DSWTCADTSTER 73.252 0.0050037 31677000.0 37331.5 44886.0 39218.9 33026.3 39615.0 39181.0 46546.0 47459.0 41627.0 33837.6 True False 36799.14596424135 44782.06922478763 35994.47343133199 35455.16427450712 37284.92358608664 37505.31996537199 48955.92412867287 49664.11839759753 36938.528908257016 39686.38407423213 0.9272486476825327 1.128398826686356 0.9069728641441726 0.8933835899030094 0.9394890579183621 0.9450425086654272 1.2335697814419766 1.2514145482415924 0.9307607576231853 1.0 15.276356500319581 -7.238234052940758 24.346585070203478 1.1248874886083953 0.9586295632542774 0.29782139903881766 0.1088052410308435 644.7845718028809 676496.2973847446 0.04186829423102504 0.032407173516169695 5.7778457988229e-08 7.238234052940758 -0.16625792535411787 KS(ph)PVGKSPPSTGSTYGSSQK ddPTM_PC-9_AZD4547_30min_R2 1 KSPVGKSPPSTGSTYGSSQK 20 2 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 KS(0.601)PVGKS(0.392)PPS(0.004)T(0.002)GSTYGSSQK 58.56399999999999 0.0054256 13968000.0 80858.0 72562.0 81179.0 102750.0 95844.0 97664.0 78894.0 105670.0 84439.0 96897.0 True False 106569.16204911975 96016.2474727515 80102.51341858365 79062.57497167516 82537.71498786508 91557.0546409842 85915.41316207034 89341.12955503352 88902.27315436487 93504.66552315142 1.1397202637202484 1.02686049873071 0.8566686268585235 0.8455468454897531 0.8827122638862234 0.9791709764291389 0.918835575544602 0.9554724254151038 0.9507790082662024 1.0 16.512750731279 -4.97631966521899 3.5586247340541015 0.9199252453984574 1.132997398444093 0.6629268356703362 0.04860668252794224 0.14319512398899845 3.728796268870082 0.013352867002101912 0.06314840391605223 1.0560399181667202e-05 4.97631966521899 0.21307215304563565 KS(ph)PVGKSPPSTGSTYGSSQK ddPTM_PC-9_Lapatinib_30min_R1 1 KSPVGKSPPSTGSTYGSSQK 20 2 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 KS(0.478)PVGKS(0.478)PPS(0.027)T(0.012)GS(0.002)T(0.001)Y(0.001)GSSQK 46.208999999999996 0.024774 13466000.0 82552.0 110370.0 112910.0 90587.0 123640.0 123310.0 101980.0 103320.0 107700.0 99027.0 True False 81374.79334181723 110114.44504611257 103626.9756452043 97249.07016937353 116367.7382855927 118036.31874964951 107260.02540802765 108120.62438820407 95569.69186872174 116143.68500481694 0.7006389829842431 0.94808809485893 0.8922308228889626 0.8373168990233109 1.001929104288076 1.0162956233458071 0.9235114711882885 0.9309212496892955 0.8228574103254782 1.0 16.825551188119377 -4.758491842356624 24.96936658010878 0.9288017970913591 0.7006386689665088 0.5463954554162249 0.06277542649833397 65.18588660284803 552106.1727297755 0.01611012955659678 0.10998550789627638 1.743846112984688e-05 4.758491842356624 -0.2281631281248503 KS(ph)QMPNT(ph)T(ph)EK ddPTM_PC-9_Lapatinib_30min_R1 1 KSQMPNTTEK 10 1 O95661 O95661 DIRAS3 GTP-binding protein Di-Ras3 3 KS(1)QMPNT(1)T(1)EK 52.49 0.028173 6530900.0 40685.0 37625.0 44783.0 38549.0 36051.0 35195.0 37643.0 37945.0 40132.0 29829.0 True False 40104.824439284785 37537.8816241731 41101.11460737911 41384.02205569425 33930.551058993035 33689.79189355216 39591.97035138643 39708.063225032936 35611.91155130494 34984.90290535589 1.1463465983535737 1.0729737260018626 1.174824315464568 1.182910873517351 0.9698626619254832 0.9629808601925415 1.1316873011908584 1.1350056718023354 1.0179222634301797 1.0 15.094444867253113 -1.5228787452803378 0.13056296220081867 0.9942570553453811 1.4888132420175708 0.2110438365124877 0.07205368105884469 163.49460868013705 1.4487944910333863 0.42466042873917054 14.888974675681064 0.02999999999999998 1.5228787452803378 0.4945561866721897 KS(ph)SADTEFSDECTTAER ddPTM_PC-9_AZD4547_30min_R2 1 KSSADTEFSDECTTAER 17 1 Q9H6S0 Q9H6S0 YTHDC2 Probable ATP-dependent RNA helicase YTHDC2 1 KS(0.836)S(0.163)ADTEFSDECTTAER 77.631 0.0034634 11048000.0 13699.0 11642.0 17876.0 16227.0 14044.0 13725.0 11368.0 14315.0 13670.0 15787.0 True False 18054.997043098883 15405.048828281655 17638.9525600291 12486.115854650847 12094.233017085857 12866.77358031114 12379.729977265919 12102.945675975217 14392.568292141888 15234.301935188822 1.1851542079125204 1.0112080549420144 1.157844490352782 0.819605381839643 0.7938816670785614 0.8445922652084855 0.8126220702420703 0.7944535776870308 0.9447474753600188 1.0 13.895035774046152 -5.764792677008485 24.9999823545832 0.8448023463848603 1.1073828573902562 0.7041580202002307 0.07662776851444904 42.098898072339786 313865.34408568824 0.020140707894851367 0.031309489343690995 1.718728676031671e-06 5.764792677008485 0.2625805110053959 KS(ph)SADTEFSDECTTAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSSADTEFSDECTTAER 17 1 Q9H6S0 Q9H6S0 YTHDC2 Probable ATP-dependent RNA helicase YTHDC2 1 KS(0.496)S(0.496)ADT(0.007)EFSDECTTAER 74.703 0.004328800000000001 9669200.0 9436.9 12584.0 13442.0 13756.0 14058.0 15702.0 15946.0 18157.0 17116.0 13286.0 True False 11034.380782729011 13833.25635524129 13762.50825906888 12985.295917553727 11303.435816197387 14878.559478208792 14435.479440957515 17680.39798893173 17366.289119709294 15694.646628081873 0.7030665324433355 0.8813996697759309 0.8768918845515205 0.8273710281771874 0.7202096411634111 0.94800219659531 0.9197709118935259 1.1265241204791971 1.1065103618603562 1.0 13.937984925917512 -7.376755932416549 1.6838042235172561 1.0847489891465294 0.8161057188572421 0.699127381418198 0.0741439404989536 0.20737588230242052 1.1429070513272332 0.0432936761468141 0.024022414872674584 4.199949491209995e-08 7.376755932416549 -0.26864327028928725 KS(ph)SGTGTEPVAK ddPTM_PC-9_AZD4547_30min_R2 1 KSSGTGTEPVAK 12 1 B8ZZI9;Q6ULP2-7;Q6ULP2-8;Q6ULP2-6;Q6ULP2;Q6ULP2-9;A0A0U1RR74 B8ZZI9 AFTPH Aftiphilin 1 KS(0.48)S(0.48)GT(0.014)GT(0.026)EPVAK 102.15 0.0011446 51605000.0 30524.0 25227.0 36597.0 55996.0 40543.0 37505.0 39826.0 45171.0 38279.0 33079.0 True False 40229.99706135854 33381.13440912742 36111.699867945 43086.987329575924 34914.30427312103 35159.806421097914 43370.436846814955 38190.85987631693 40302.34979187265 31920.914278463973 1.260302155208018 1.0457449344315495 1.1312865149451066 1.3498042992661192 1.0937751960530968 1.101466145812093 1.3586840423325723 1.1964212410445614 1.2625687798379686 1.0 14.962214353356451 KS(ph)SGTGTEPVAK ddPTM_PC-9_Lapatinib_30min_R1 4 KSSGTGTEPVAK 12 1 B8ZZI9;Q6ULP2-7;Q6ULP2-8;Q6ULP2-6;Q6ULP2;Q6ULP2-9;A0A0U1RR74 B8ZZI9 AFTPH Aftiphilin 1 KS(0.874)S(0.125)GTGTEPVAK;KS(0.499)S(0.499)GT(0.001)GTEPVAK;KS(0.834)S(0.159)GT(0.005)GT(0.002)EPVAK;KS(0.621)S(0.367)GT(0.005)GT(0.008)EPVAK 115.04 0.00033978 96072500.0 276144.0 181259.0 203701.0 177301.0 197135.0 175260.0 167497.0 194621.0 189343.0 160934.0 True False 272206.13592139276 180839.30592201976 186953.49008859936 190340.3069987975 185539.90688232228 167764.53835101458 176169.1750908846 203663.80215889154 168017.197469818 188751.2274689242 1.4421423350277736 0.9580828074444865 0.9904756254863518 1.008418909647276 0.9829864916394749 0.8888129661495058 0.9333405533476009 1.0790065044341104 0.8901515488024054 1.0 17.5261265009014 -4.760474994711242 24.9999601172437 0.9711520745615466 1.442142888712357 0.8724642493382014 0.05413722782898313 7.703037660122829 199584.85197027764 0.013270102667695462 0.07852100047484803 1.7359012076397483e-05 4.760474994711242 0.47099081415081046 KS(ph)SISSISGR ddPTM_PC-9_Lapatinib_30min_R1 1 KSSISSISGR 10 1 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 KS(0.749)S(0.215)IS(0.018)S(0.018)ISGR 82.705 0.021372 8599000.0 17184.0 24475.0 20589.0 24317.0 28177.0 26333.0 25455.0 29835.0 26876.0 20259.0 True False 16938.953008840344 24418.329641239525 18896.25189583835 26105.353299134018 26519.68425811342 25206.798975221165 26772.935347728442 31221.243018022313 23848.941863173302 23760.741156579334 0.712896659965927 1.0276754197323557 0.7952719896789074 1.0986758841866118 1.116113511920908 1.0608591208966316 1.126771895341953 1.3139843918285004 1.003712035159709 1.0 14.536292217634461 -5.7868068709658385 12.186354576517296 1.1158167879437793 0.8635416673251645 0.5272742694394861 0.11089625609247343 0.6109169318421968 292.19995215256193 0.030031008514443954 0.0449290013505756 1.633778321116326e-06 5.7868068709658385 -0.2522751206186148 KS(ph)SLVTSK ddPTM_PC-9_AZD4547_30min_R2 1 KSSLVTSK 8 1 A6NMQ3;Q5T5H1;O43768-2;O43768;O43768-9;O43768-3;O43768-4;A0A1W2PRU0;O43768-6;O43768-5;O43768-7 A6NMQ3 ENSA Alpha-endosulfine 1 KS(0.862)S(0.136)LVTS(0.001)K 62.799 0.027747000000000004 451410000.0 189060.0 119120.0 148050.0 200590.0 193380.0 126620.0 148200.0 180440.0 223680.0 212040.0 True False 249177.147307707 157623.21048143881 146086.7602658483 154347.07458460677 166532.52498177634 118702.43138353362 161389.51289855785 152557.1440987056 235503.26814822957 204616.54413995327 1.217776149797913 0.7703346332231472 0.7139538050546301 0.7543235334823988 0.8138761490755689 0.5801213771958915 0.7887412700518045 0.7455758024842792 1.1509492995207193 1.0 17.642563272421903 -8.257189754191469 24.965506297816695 1.075474663864738 0.7858486256497945 0.32859405068162195 0.1578281159319886 364.95596882023256 2144059.6441961965 0.11470600025082363 0.039900406500584164 5.531083894343284e-09 8.257189754191469 -0.28962603821494337 KS(ph)SMCSLAQPATTTAR ddPTM_PC-9_AZD4547_30min_R2 1 KSSMCSLAQPATTTAR 16 1 H3BPV0 H3BPV0 MTSS1L 1 KS(0.808)S(0.189)MCS(0.003)LAQPATTTAR 57.788000000000004 0.020899 7711300.0 27449.0 16447.0 25965.0 38221.0 31267.0 35442.0 27594.0 30898.0 28101.0 33596.0 True False 36177.21102533186 21763.171111385356 25620.687134770393 29409.738958563496 26926.11675770603 33225.80613722313 30049.81254333882 26123.424065405678 29586.361490671476 32419.81426582655 1.1158981581046856 0.6712922823350573 0.7902786525762716 0.9071532217124406 0.8305450653395204 1.0248610884932234 0.9268965052342718 0.8057857411275227 0.9126012027113372 1.0 14.98458820518163 KS(ph)SMCSLAQPATTTAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSSMCSLAQPATTTAR 16 1 H3BPV0 H3BPV0 MTSS1L 1 KS(0.775)S(0.132)MCS(0.093)LAQPATTTAR 51.235 0.033155000000000004 7437300.0 42009.0 29656.0 29520.0 34100.0 34873.0 25472.0 20130.0 41077.0 23025.0 20169.0 True False 49120.293984429525 32600.051690323853 30223.868755223415 32189.48755369162 28039.885987925132 24136.203479106764 18223.14067142072 39998.77227467909 23361.697065979577 23825.48004228385 2.0616706944520806 1.3682851985549709 1.2685523524220348 1.3510530531415903 1.1768865071411716 1.0130416443350339 0.7648593287136092 1.6788233522972875 0.9805341602569526 1.0 14.540217661791504 -1.830398921115527 0.8695331530777541 1.1374108783499677 199.9999998823811 0.5866601124363203 0.23149715455300585 295.2946559849748 1.3772017296819072 0.07821809120648632 115451.51091822096 0.01477750377229359 1.830398921115527 198.86258900403115 KS(ph)SPPASSPQPEAPTSSWR ddPTM_PC-9_AZD4547_30min_R2 1 KSSPPASSPQPEAPTSSWR 19 1 P43250-2 P43250-2 1 KS(0.918)S(0.081)PPAS(0.001)SPQPEAPTSSWR 68.26100000000001 0.0039304000000000006 3883900.0 8470.2 6304.3 11555.0 14366.0 15465.0 9162.8 8342.9 15058.0 7603.1 9457.1 True False 11163.54740889526 8342.041687694209 11401.773150097124 11054.14065248746 13317.951695331301 8589.848667517288 9085.401937661143 12731.132098416687 8004.984343963713 9126.009807517208 1.2232670843395004 0.9140951920545566 1.249371126108734 1.2112786295037756 1.4593400594815424 0.9412491163927659 0.9955503149007559 1.395038178452306 0.8771614881862069 1.0 13.155768488878355 KS(ph)SPSTGSLDSGNESK ddPTM_PC-9_AZD4547_30min_R2 2 KSSPSTGSLDSGNESK 16 1 A0A0U1RQT1;A0A087X1H5;Q15057 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 KS(0.499)S(0.499)PS(0.002)T(0.001)GSLDSGNESK;KS(0.435)S(0.435)PS(0.123)T(0.007)GS(0.001)LDSGNESK 84.15899999999999 0.0023103999999999998 120937000.0 86588.0 87190.0 96569.0 127147.0 99099.0 105620.0 102540.0 111592.0 90171.0 102399.0 True False 114121.18285771583 115372.46240662056 95288.4319629363 97835.2235515679 85340.81442325465 99015.56470327571 111665.86135369849 94348.02052905536 94937.25497225508 98814.04217783005 1.1549085569471835 1.167571529955138 0.9643207570787469 0.9900943367492181 0.8636506769925635 1.0020394118184437 1.1300606562854674 0.9548037753506992 0.9607668392049165 1.0 16.59242845314894 -5.258896304163865 24.719772425746115 0.9834949338125686 1.1612400659877753 0.5697499218820147 0.06188020699160311 138.88304527152954 1349977.610460983 0.017040127997878712 0.04096875128715514 5.50939227627552e-06 5.258896304163865 0.1777451321752067 KS(ph)SPSTGSLDSGNESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 KSSPSTGSLDSGNESK 16 1 A0A0U1RQT1;A0A087X1H5;Q15057 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 KS(0.487)S(0.487)PS(0.024)T(0.001)GSLDSGNESK;KS(0.843)S(0.153)PS(0.004)TGSLDSGNESK;KS(0.74)S(0.13)PS(0.125)T(0.004)GSLDSGNESK;KS(0.444)S(0.444)PS(0.096)T(0.014)GS(0.001)LDSGNESK;KS(0.491)S(0.491)PS(0.016)T(0.001)GSLDSGNESK 123.63 1.7542999999999998e-05 135028600.0 162673.0 159639.0 164326.0 186249.0 196847.0 167579.0 180982.0 164711.0 144543.0 146908.0 True False 190210.32596179593 175486.90490260354 168244.15504982564 175814.07235740495 158276.24342801308 158790.86223403053 163838.07476378843 160387.51077573028 146656.66792651007 173541.25747691197 1.0960524818549366 1.0112114401726657 0.96947640864138 1.0130966832529456 0.912038127008906 0.9150035244797979 0.9440871706578797 0.9242039219236862 0.8450824320321717 1.0 17.40491916249362 -3.5209350079906083 0.4921286263239883 0.9173726806407616 1.6176288074652752 0.6088095792034478 0.041777245722629267 9.425756344420886 0.6702256199483103 0.023846245783106623 4.99847096860778 0.0003013456953168658 3.5209350079906083 0.7002561268245135 KS(ph)SPSTGSLDSGNESK ddPTM_PC-9_Lapatinib_30min_R1 1 KSSPSTGSLDSGNESK 16 1 A0A0U1RQT1;A0A087X1H5;Q15057 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 KS(0.94)S(0.057)PS(0.003)T(0.001)GSLDSGNESK 156.29 6.0962e-05 7227800.0 30848.0 34208.0 38600.0 35954.0 38445.0 29612.0 31325.0 36071.0 36205.0 24655.0 True False 30408.10186316962 34128.793477733234 35426.4570003089 38598.17709902803 36183.74068577813 28345.56378894351 32946.85522559785 37746.990343659585 32127.21164444818 28916.58389927752 1.0515800195862475 1.1802498385221063 1.22512593893202 1.3348110977933463 1.2513144986909115 0.9802528503255089 1.1393757762105856 1.3053751603280737 1.1110306720999252 1.0 14.819609507126474 KS(ph)SPSVKPAVDPAAAK ddPTM_PC-9_AZD4547_30min_R2 1 KSSPSVKPAVDPAAAK 16 2 H3BV90;Q6FI81-3;Q6FI81;H3BPG7;H3BT65 H3BV90 CIAPIN1 Anamorsin 1 KS(0.49)S(0.49)PS(0.02)VKPAVDPAAAK 43.12 0.044718 113150000.0 155080.0 179320.0 191430.0 232940.0 209300.0 226680.0 177710.0 207150.0 156300.0 179200.0 True False 204392.21413561373 237281.68320627615 188891.51312186013 179239.2818871245 180242.3077809795 212505.663765751 193525.8457301128 175139.72733344554 164561.69890722577 172926.26254423472 1.1819616704161984 1.3721552742492151 1.0923240365155147 1.0365070015971396 1.04230731138871 1.2288802211948102 1.119123508961565 1.0128000498978262 0.9516293042251504 1.0 17.399797464094092 -1.5228787452803492 0.2095247118101154 0.9804021581154201 2.4552794068071404 0.4223795534033491 0.09140924453560115 53.208384039126045 0.6614562563321098 0.16658463145540647 26.130781436161854 0.029999999999999197 1.5228787452803492 1.4748772486917203 KS(ph)SPSVKPAVDPAAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSSPSVKPAVDPAAAK 16 2 H3BV90;Q6FI81-3;Q6FI81;H3BPG7;H3BT65 H3BV90 CIAPIN1 Anamorsin 1 KS(0.486)S(0.486)PS(0.029)VKPAVDPAAAK 49.865 0.031217 44077000.0 130050.0 115130.0 110180.0 138140.0 120670.0 119400.0 131500.0 133630.0 102170.0 107870.0 True False 152064.89639541702 126559.34553233683 112807.10905997713 130400.46365592263 97025.57973684292 113138.45380831299 119043.36802244555 130122.35409268831 103664.04296334999 127425.97710155013 1.1933586844245367 0.9931989411505736 0.885275605695982 1.0233428585130804 0.7614270021215526 0.8878758976919524 0.9342158540214748 1.0211603399280929 0.8135236261970081 1.0 16.959299890298553 -4.767256614029758 2.3581734246102197 0.9142571797721779 1.2673522671510011 0.5135599594349944 0.08148503494843781 0.484422145732385 3.1748160382016413 0.020898441601488217 0.36215024655052136 1.709005207150777e-05 4.767256614029758 0.3530950873788232 KS(ph)SPSVKPAVDPAAAK ddPTM_PC-9_Lapatinib_30min_R1 1 KSSPSVKPAVDPAAAK 16 2 H3BV90;Q6FI81-3;Q6FI81;H3BPG7;H3BT65 H3BV90 CIAPIN1 Anamorsin 1 KS(0.478)S(0.478)PS(0.044)VKPAVDPAAAK 49.066 0.032817 101270000.0 903110.0 691800.0 847260.0 657660.0 778540.0 806570.0 691030.0 688560.0 778720.0 465130.0 True False 890231.4857899095 690198.1796040644 777601.5533181791 706026.510289446 732747.8078685325 772074.8813065022 726808.1521642419 720553.0113118623 691012.3533148643 545527.1007532323 1.6318739885896216 1.2651950355006722 1.4254132420635233 1.294209782272238 1.3431923122733898 1.415282357632583 1.3323043917721178 1.3208381587586837 1.266687488780584 1.0 19.057291343123396 -13.703498448916827 0.15158559863294693 2.3506380416137256e-11 1.4799742192027852 0.6461532655725641 0.08945616241794845 64.12303902733566 0.7200816443802904 19.882971311397633 0.43653710974672355 1.9792540901329026e-14 13.703498448916827 1.4799742191792788 KS(ph)SS(ph)S(ph)S(ph)EDR ddPTM_PC-9_AZD4547_30min_R2 1 KSSSSSEDR 9 1 H7C560;P15056;A0A2R8Y679;A0A2R8Y492;A0A2R8YDP5;A0A2R8Y8E0;A0A2U3TZI2 H7C560 BRAF Serine/threonine-protein kinase B-raf 4 KS(0.998)S(0.442)S(0.888)S(0.836)S(0.836)EDR 50.473 0.039932999999999996 0.0 2008.9 2733.1 3051.2 3236.4 4176.1 4006.0 2924.7 4429.9 2888.1 2733.5 True False 2647.688412284207 3616.521126316493 3010.7390943813357 2490.297981881556 3596.320599733141 3755.5041867195914 3184.9926341053524 3745.360743975036 3040.759069826991 2637.8009970126454 1.0037483552712123 1.3710363785639117 1.1413821959241994 0.944081067791642 1.3633782850965768 1.4237253647916441 1.207442349787725 1.419879948569555 1.152762878348557 1.0 11.365120012461349 -4.737969910731459 24.37264369917306 1.2365923170913622 1.0037470083421107 0.14065323505281524 0.16163040076136878 2987.019251965272 3101747.7139404044 0.04055363349012759 2.276917745239803 1.8282268769827024e-05 4.737969910731459 -0.23284530874925147 KS(ph)STPEEVK ddPTM_PC-9_Lapatinib_30min_R1 1 KSSTPEEVK 9 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 1 KS(0.775)S(0.133)T(0.092)PEEVK 58.674 0.035480000000000005 20126000.0 65450.0 100010.0 67369.0 68881.0 92403.0 64057.0 98222.0 100350.0 84639.0 68201.0 True False 64516.67099794002 99778.43298959623 61830.18087186042 73946.73852027996 86968.03721128764 61317.43143416029 103307.45455606298 105012.62734568612 75106.06453181748 79989.45197787984 0.8065647332573469 1.247394881730016 0.7729791784166598 0.9244561212987067 1.0872438185391948 0.7665689652570306 1.2915134683586964 1.3128309389433765 0.9389496074130773 1.0 16.287522147268035 -7.269952464523101 24.977744591196274 1.1618927401589947 0.9476225932012776 0.23305144860603333 0.17566134147244433 894.0335130357137 2623121.573689078 0.07024080210473027 0.048225207478958546 5.3709058012354836e-08 7.269952464523101 -0.21427014695771707 KS(ph)SVNGSSATSSG ddPTM_PC-9_AZD4547_30min_R2 1 KSSVNGSSATSSG 13 1 R4GMX3;P35226 R4GMX3 COMMD3-BMI1;BMI1 Polycomb complex protein BMI-1 1 KS(0.473)S(0.473)VNGS(0.008)S(0.046)AT(0.001)SSG 87.831 0.010142 45009000.0 27319.0 19674.0 27494.0 39656.0 27871.0 24396.0 21577.0 25853.0 29365.0 26763.0 True False 36005.873729499865 26033.235753960955 27129.411595739544 30513.921879092504 24001.592738479063 22870.51426340767 23497.31119981235 21858.0128928388 30917.173950164328 25826.035516023196 1.394169604822266 1.008022920816058 1.0504675244834887 1.1815178469866507 0.9293564520806069 0.8855603969574875 0.9098303603444655 0.8463557203457526 1.1971320155190852 1.0 14.65653857583749 -1.70473564913238 0.9601223067335624 0.9761844191496164 199.99999999066273 0.5035377641592165 0.11435851173603198 734.7564531932958 1.8328775006743196 0.038173216218308215 320422.7017307771 0.01973623696303549 1.70473564913238 199.02381557151313 KS(ph)SVNGSSATSSG ddPTM_PC-9_Lapatinib_30min_R1 2 KSSVNGSSATSSG 13 1 R4GMX3;P35226 R4GMX3 COMMD3-BMI1;BMI1 Polycomb complex protein BMI-1 1 KS(0.408)S(0.408)VNGS(0.014)S(0.036)AT(0.129)S(0.003)S(0.002)G;KS(0.352)S(0.352)VNGS(0.292)S(0.002)AT(0.001)SSG 82.515 0.015316999999999999 56047000.0 77321.0 86945.0 95593.0 96427.0 179296.0 239080.0 267670.0 273530.0 285850.0 212130.0 True False 76218.38836106515 86743.68419438468 87733.71253965121 103518.56325104249 168750.1617894986 228855.10572270042 281528.6428806316 286239.20237035904 253654.56286605503 248796.3878545429 0.306348452316059 0.3486533102124408 0.3526325815909519 0.4160774364279111 0.6782661245393853 0.9198489885492187 1.1315624206137003 1.1504958124139117 1.0195267103891894 1.0 17.92460601431784 -6.582669794920614 1.4879770378366675 1.0913015996224957 0.3330731360616998 0.9781717727949585 0.048985890115090434 0.05104909551726321 0.23305505386045514 0.020767123763676138 0.021849929526735364 2.6141482019769825e-07 6.582669794920614 -0.7582284635607959 down KS(ph)TGSPTQETQAPFIAK ddPTM_PC-9_AZD4547_30min_R2 1 KSTGSPTQETQAPFIAK 17 1 O15231-3;O15231-2 O15231-3 ZNF185 Zinc finger protein 185 1 KS(0.455)T(0.455)GS(0.086)PT(0.004)QETQAPFIAK 95.227 0.00076598 46766000.0 83688.0 58691.0 103400.0 158960.0 153420.0 106230.0 80454.0 107040.0 89223.0 125470.0 True False 110299.0431814631 77661.71798494065 102028.84843964019 122314.22790751829 132120.28122196734 99587.42130684514 87614.25013995005 90499.42753450126 93939.14562763546 121077.33349009547 0.9109801149567432 0.6414224342931507 0.8426750531963647 1.0102157388321078 1.0912057394522585 0.8225108567904803 0.723622230639207 0.7474514421966885 0.7758607075313564 1.0 16.885569282308396 -10.03387505612519 11.854192268187758 0.9999870567543124 0.8404981308548619 0.12289465333991634 0.12770323195309524 0.0 0.0 0.1372701834549678 0.033292909743102714 9.249642422368119e-11 10.03387505612519 -0.15948892589945052 KS(ph)TGSPTQETQAPFIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSTGSPTQETQAPFIAK 17 1 O15231-3;O15231-2 O15231-3 ZNF185 Zinc finger protein 185 1 KS(0.328)T(0.328)GS(0.328)PT(0.012)QET(0.004)QAPFIAK 68.88 0.007714699999999999 37916000.0 80324.0 43551.0 74100.0 94379.0 101570.0 104090.0 90322.0 112600.0 95058.0 75121.0 True False 93921.26672868468 47874.45546146798 75866.82502581495 89091.25061084627 81668.08762634569 98631.33716002751 81766.04628534845 109644.36930956163 96448.04341793219 88739.84264249133 1.0583889257846433 0.5394922284721771 0.8549353116554615 1.0039599796200975 0.9203091327912782 1.11146621656054 0.9214130186680811 1.2355709233257146 1.0868629078653553 1.0 16.437294374457657 -6.093508933351589 1.1530702491578935 1.0771709348780332 0.7853377550867372 0.3267273691353846 0.14617567407173826 0.5158502934692785 1.4043157850414614 0.05669379693233711 0.10060781301985905 8.062896159662337e-07 6.093508933351589 -0.29183317979129597 KS(ph)TGSPTQETQAPFIAK ddPTM_PC-9_Lapatinib_30min_R1 2 KSTGSPTQETQAPFIAK 17 1 O15231-3;O15231-2 O15231-3 ZNF185 Zinc finger protein 185 1 KS(0.615)T(0.168)GS(0.123)PT(0.088)QET(0.006)QAPFIAK;KS(0.689)T(0.071)GS(0.227)PT(0.013)QETQAPFIAK 116.98 6.0708e-05 65063000.0 273960.0 136197.0 192602.0 165354.0 180350.0 166494.0 128404.0 120372.0 188128.0 130178.0 True False 270053.2801618889 135881.64421441886 176767.00702522052 177514.68476477347 169742.16758174248 159373.4397364703 135052.13083440287 125964.92255959057 166939.04356433518 152679.09384871862 1.7687639699346787 0.8899819928788454 1.1577682482211304 1.1626653020397348 1.1117577613470166 1.043845858126357 0.8845489413777806 0.825030587910106 1.0933981814808644 1.0 17.22014300372514 -4.755251891204892 24.999648040805734 1.021643964880158 1.7687651998843994 0.7988701296996787 0.1128867916549513 97.49542770289948 393878.34941824136 0.030720640605332698 0.277686400042141 1.7569043122482274e-05 4.755251891204892 0.7471212350042413 KS(ph)VIT(ph)YS(ph)PTTGTCQMSLFAS(ph)PTSSEEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSVITYSPTTGTCQMSLFASPTSSEEQK 28 1 Q13352-4;Q13352-3;Q13352-2;Q13352;Q13352-5 Q13352-4 ITGB3BP Centromere protein R 4 KS(0.647)VIT(0.647)Y(0.398)S(0.418)PT(0.226)T(0.226)GT(0.227)CQMS(0.245)LFAS(0.937)PT(0.009)S(0.009)S(0.009)EEQK 40.756 0.028856 9211900.0 16968.0 16700.0 22873.0 19972.0 20267.0 29451.0 26416.0 21486.0 24498.0 22055.0 True False 19840.347266723806 18357.865633544938 23418.37906633555 18853.03359009764 16295.826837876819 27906.537714477567 23913.685244721783 20922.015266298786 24856.236904337347 26053.396912716056 0.7615263120272886 0.7046246481810935 0.898860871954305 0.7236305366727789 0.6254780093540587 1.0711285675326674 0.917872065774658 0.8030436620756827 0.9540497535738074 1.0 14.669183866818377 -6.758949642580453 24.999999978293587 0.9349498608883586 0.7483042991529757 0.5644449730579228 0.09015379943168636 57.352024086806736 575885.8254090636 0.031543715105932235 0.03015482176088276 1.742008851516132e-07 6.758949642580453 -0.18664556173538294 KS(ph)VSNGALR ddPTM_PC-9_Lapatinib_30min_R1 2 KSVSNGALR 9 1 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 KS(0.651)VS(0.349)NGALR;KS(0.999)VS(0.001)NGALR 56.434 0.039772 49221000.0 285409.0 246525.0 241084.0 205664.0 223217.0 202876.0 196911.0 182768.0 242834.0 185431.0 True False 281339.0153223999 245954.18650895072 221263.0041311525 220789.21663499184 210087.81492150697 194199.46640705466 207106.08808707743 191260.06850738774 215483.47776461605 217482.50127872394 1.293616790630148 1.1309148325167444 1.0173830208416792 1.0152045122565059 0.9659987064994254 0.8929429506522462 0.9522885145672103 0.8794273901709005 0.9908083477872734 1.0 17.73053980029931 -4.1416480916155125 0.7111922457668276 0.9369389367002229 1.9576931433287106 0.8883148825376256 0.03831991462469025 1.8631741503207448 0.3719064988611049 0.014943616695565392 1.883404068651799 7.216920286502737e-05 4.1416480916155125 1.0207542066284878 KS(ph)VSSPTSSNTPTPTK ddPTM_PC-9_AZD4547_30min_R2 2 KSVSSPTSSNTPTPTK 16 1 Q5M775;Q5M775-4;Q5M775-2;Q5M775-5;Q5M775-3 Q5M775 SPECC1 Cytospin-B 1 KS(0.719)VS(0.117)S(0.153)PT(0.007)S(0.003)SNTPTPTK;KS(0.639)VS(0.164)S(0.164)PT(0.028)S(0.002)SNTPTPT(0.002)K 103.4 0.00062763 25252000.0 59475.0 57682.0 63949.0 65391.0 110836.0 67384.0 64542.0 114574.0 82684.0 80474.0 True False 78386.81284314959 76326.57846701097 63100.99447646571 50316.11523087899 95448.33456862214 63170.46782773664 70286.11296557852 96869.22094859842 87054.50743726846 77656.62975437922 1.0094027141157151 0.9828726627517177 0.8125641645284937 0.6479307097156319 1.2291073520769116 0.8134587868098194 0.905088376715382 1.2474043910350843 1.121018356225526 1.0 16.24482147615779 -7.744278261113329 24.837278992767228 1.138158510387212 0.9110464074004664 0.27729617368244075 0.15355762921307958 261.3740586962311 378287.57491902856 0.07259866770536028 0.04178027180746134 1.801862881538431e-08 7.744278261113329 -0.22711210298674567 KS(ph)VSSPTSSNTPTPTK ddPTM_PC-9_Lapatinib_30min_R1 1 KSVSSPTSSNTPTPTK 16 1 Q5M775;Q5M775-4;Q5M775-2;Q5M775-5;Q5M775-3 Q5M775 SPECC1 Cytospin-B 1 KS(0.969)VS(0.011)S(0.019)PT(0.001)SSNTPTPTK 134.58 2.4823e-06 8924400.0 37577.0 41670.0 45177.0 63795.0 38396.0 20740.0 25878.0 25641.0 51127.0 50928.0 True False 37041.145089222155 41573.51567519718 41462.72144826309 68486.69711388132 36137.62276944044 19852.998547301362 27217.83621797355 26832.374467072583 45368.53886882208 59730.83694270561 0.6201343725478412 0.6960142834609013 0.6941593918738244 1.1465886068124982 0.6050078086818704 0.33237435742520316 0.4556747839324796 0.44922147152919445 0.759549693106427 1.0 15.866188316373915 -4.679018690902309 17.86958413117045 0.6593371707409803 0.6200895247729377 0.0 0.23697021202695842 29381.61178769143 6339528.73158442 0.06288242693255197 221.5916509626259 2.094022332649427e-05 4.679018690902309 -0.039247645968042644 KS(ph)WYS(ph)T(ph)HS(ph)LVGDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSWYSTHSLVGDK 13 1 Q8IYQ7 Q8IYQ7 THNSL1 Threonine synthase-like 1 4 KS(0.999)WY(0.539)S(0.821)T(0.821)HS(0.821)LVGDK 57.858999999999995 0.030402 1695100.0 3154.1 3414.0 3410.3 4444.1 3710.4 4158.6 4136.1 3052.8 3868.0 3222.2 True False 3688.0268336853796 3752.9193576600233 3491.614485634773 4195.1114849666 2983.3737553292626 3940.5156952030998 3744.298665229171 2972.6672347089698 3924.5621824629334 3806.359353078836 0.9689118897043335 0.9859603388798309 0.9173107848607418 1.1021322728168887 0.7837866787107507 1.0352453170286586 0.9836955258048702 0.7809738805413837 1.0310540383656859 1.0 11.894196055530864 -6.236713326998367 24.999205762552844 0.9322089998131691 0.9875868920905178 0.07893061840444171 0.09536526959581988 2255.248906883267 2280162.728378676 0.027061151447338793 0.034922525408307564 5.798112971855402e-07 6.236713326998367 0.055377892277348684 KS(ph)Y(ph)T(ph)LK ddPTM_PC-9_Lapatinib_30min_R1 1 KSYTLK 6 1 J3KTG8;J3QKW5;J3QLE6;J3KRI5;X6R3Y6;P55286;Q9HBT6 J3KTG8 CDH8;CDH20 Cadherin-8;Cadherin-20 3 KS(1)Y(1)T(1)LK 46.766000000000005 0.037394 0.0 5322.2 5290.4 5713.9 6041.1 5689.4 5136.1 6074.2 4857.9 6289.6 4396.6 True False 5246.304452028052 5278.150403841205 5244.125198291844 6485.382646518831 5354.76067779077 4916.440975833873 6388.692354711143 5083.615768635852 5581.199015575786 5156.5464518987455 1.0174066113757698 1.0235824408985363 1.0169839925248516 1.2576988701674123 1.0384393368199056 0.9534367665830955 1.23894789163757 0.985856680640191 1.0823521261057727 1.0 12.332189442401706 KSAEPSANTTLVS(ph)ETEEEGSVPAFGAAAK ddPTM_PC-9_AZD4547_30min_R2 5 KSAEPSANTTLVSETEEEGSVPAFGAAAK 29 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 1 KSAEPSANTTLVS(0.497)ET(0.497)EEEGS(0.005)VPAFGAAAK;KSAEPSANTTLVS(0.721)ET(0.272)EEEGS(0.006)VPAFGAAAK;KSAEPSANTTLVS(0.779)ET(0.219)EEEGS(0.002)VPAFGAAAK;KSAEPSANTT(0.001)LVS(0.884)ET(0.111)EEEGS(0.004)VPAFGAAAK;KSAEPSANTTLVS(0.932)ET(0.054)EEEGS(0.014)VPAFGAAAK 104.14 1.5197e-11 37099000.0 181224.6 198165.6 224652.5 202808.6 219502.9 252754.2 250273.0 292329.0 250002.8 233551.2 True False 238850.25309415156 262218.7548604822 221673.4610646639 156054.21063163492 189028.71123085293 236949.43991786364 272546.8121569555 247156.27010214224 263217.4376171684 225374.64357545317 1.0597920391793627 1.1634793990154175 0.9835776445296954 0.6924213307935395 0.8387310490302251 1.0513580239497322 1.2093055715281011 1.096646304930913 1.1679106107118296 1.0 17.781965684508926 -6.993907247634798 22.73515851287501 1.1270641173077158 0.9471785111078588 0.2860100642843857 0.1276547989272103 72.8330373384514 271770.73973016243 0.050786606493786475 0.04462085618956035 1.0141279501327835e-07 6.993907247634798 -0.17988560619985705 KSAEPSANTTLVS(ph)ETEEEGSVPAFGAAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 KSAEPSANTTLVSETEEEGSVPAFGAAAK 29 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 1 KSAEPSANTTLVS(0.749)ET(0.247)EEEGS(0.003)VPAFGAAAK;KSAEPSANT(0.002)T(0.003)LVS(0.885)ET(0.106)EEEGS(0.004)VPAFGAAAK;KSAEPSANT(0.001)T(0.003)LVS(0.492)ET(0.492)EEEGS(0.012)VPAFGAAAK;KSAEPSANTT(0.004)LVS(0.488)ET(0.488)EEEGS(0.02)VPAFGAAAK;KSAEPSANTTLVS(0.795)ET(0.204)EEEGSVPAFGAAAK 134.26 8.8788e-12 47722400.0 194964.4 227382.0 224703.2 223985.0 265181.0 186287.2 248997.0 192953.0 188988.0 176705.9 True False 227968.02219757426 249954.9822447133 230060.97647963115 211435.84661916769 213220.6866677368 176517.97129212692 225410.20157783097 187888.18820060306 191751.5919698307 208741.28086686533 1.092107997281916 1.1974391515022558 1.102134544371046 1.0129086385841473 1.0214591276927558 0.8456303926040851 1.0798544525632046 0.9001007726901785 0.9186088691873525 1.0 17.67135641184221 -5.881384194527813 1.6161438964620596 0.9536902668494313 1.148951738928836 0.5749051789169701 0.06598912032646048 0.25684818568079687 1.3659439932382054 0.021050592417804687 0.0402617772529488 1.3140618454058531e-06 5.881384194527813 0.1952614720794047 KSAEPSANTTLVS(ph)ETEEEGSVPAFGAAAK ddPTM_PC-9_Lapatinib_30min_R1 8 KSAEPSANTTLVSETEEEGSVPAFGAAAK 29 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 1 KSAEPSANTTLVS(0.837)ET(0.161)EEEGS(0.002)VPAFGAAAK;KSAEPSANTTLVS(0.53)ET(0.382)EEEGS(0.087)VPAFGAAAK;KSAEPSANTTLVS(0.823)ET(0.172)EEEGS(0.005)VPAFGAAAK;KSAEPSANTT(0.001)LVS(0.852)ET(0.138)EEEGS(0.009)VPAFGAAAK;KS(0.001)AEPSANT(0.002)T(0.001)LVS(0.484)ET(0.484)EEEGS(0.028)VPAFGAAAK;KSAEPSANTT(0.001)LVS(0.44)ET(0.44)EEEGS(0.119)VPAFGAAAK;KSAEPSANTTLVS(0.916)ET(0.083)EEEGS(0.001)VPAFGAAAK;KSAEPS(0.001)ANT(0.001)T(0.004)LVS(0.723)ET(0.122)EEEGS(0.149)VPAFGAAAK 119.87 8.3703e-14 109086500.0 239384.6 443266.3 454713.2 420124.7 530335.3 534898.7 528759.2 560303.4 516181.0 473934.8 True False 235970.93170624078 442239.9441165503 417328.4359397111 451022.0719329154 499142.0203333167 512022.3295107708 556135.7641373642 586337.1414521268 458043.26015309745 555853.7987015747 0.4245197788653204 0.7956047887944343 0.7507881333446914 0.8114041371786306 0.8979735705670597 0.9211456874214221 1.0005072654652145 1.0548405764640962 0.8240354949863543 1.0 19.084345947989014 -4.405461130370491 0.5561713079345832 0.9700714573822394 1.745177947121202e-14 0.7827586829323295 0.07943238094658049 2.719243030914141 0.4724167376361416 0.042090774051604225 1.8649665933800452 3.931324289328051e-05 4.405461130370491 -0.970071457382222 down KSAEPSANTTLVSET(ph)EEEGSVPAFGAAAK ddPTM_PC-9_AZD4547_30min_R2 2 KSAEPSANTTLVSETEEEGSVPAFGAAAK 29 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 1 KSAEPSANTTLVS(0.181)ET(0.784)EEEGS(0.035)VPAFGAAAK;KSAEPSANTTLVS(0.395)ET(0.604)EEEGS(0.002)VPAFGAAAK 112.74 3.1365e-12 36584000.0 192564.0 228532.0 259562.0 205124.0 245177.0 290836.0 250535.0 303107.0 259421.0 259535.0 True False 253795.3464199796 302400.49981316476 256120.03828520223 157835.83093420853 211138.40561307766 272649.9789437785 272832.12964939425 256268.77785594264 273133.46444153157 250448.75864630568 1.0133623651870447 1.2074346123640705 1.0226444709470721 0.6302120712728745 0.8430403358926456 1.088645758986677 1.089373056285335 1.0232383631729485 1.0905762357052133 1.0 17.934155935306904 -6.788095120324141 24.884447753979114 1.0617570147630786 0.9450206451633194 0.14370674192955846 0.14024101166924227 498.96022117960433 465800.2570373858 0.05634549222404173 0.049706149419248405 1.6289392189972068e-07 6.788095120324141 -0.1167363695997592 KSAEPSANTTLVSET(ph)EEEGSVPAFGAAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KSAEPSANTTLVSETEEEGSVPAFGAAAK 29 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 1 KSAEPSANTTLVS(0.081)ET(0.892)EEEGS(0.027)VPAFGAAAK;KSAEPSANT(0.001)TLVS(0.181)ET(0.523)EEEGS(0.295)VPAFGAAAK;KSAEPSANTTLVS(0.156)ET(0.755)EEEGS(0.09)VPAFGAAAK 100.71 6.3037e-11 20513700.0 74954.3 87249.6 90291.0 96907.0 103561.0 66500.2 95911.0 76067.5 81903.6 77640.7 True False 87642.58257509384 95911.16367548154 92443.87987052456 91477.61496673308 83268.96546885869 63012.81244508851 86825.61574449242 74070.80872517836 83101.28520361187 91716.34430655715 0.9555830341662226 1.0457368792949644 1.0079324527102351 0.9973970905444494 0.9078966905891547 0.6870401663030903 0.9466754960738761 0.8076075129815521 0.9060684421290289 1.0 16.484891231678056 -6.352461508859308 4.041515598308588 0.8569473965859594 1.005670730925367 0.35917038381452593 0.08193852828858107 0.22249481173876035 6.605413002318074 0.024919661808990582 0.028699603588224553 4.4415902504771526e-07 6.352461508859308 0.14872333433940754 KSAEPSANTTLVSETEEEGS(ph)VPAFGAAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSAEPSANTTLVSETEEEGSVPAFGAAAK 29 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 1 KSAEPSANTTLVS(0.087)ET(0.227)EEEGS(0.686)VPAFGAAAK 73.072 2.4156e-05 10220000.0 41406.0 45158.0 36499.0 47896.0 51637.0 37575.0 48272.0 34172.0 38227.0 37763.0 True False 48415.21799422239 49640.987801174975 37369.27458322831 45212.542400927094 41519.10052930604 35604.50085299294 43699.32670098464 33275.02120822684 38785.99755662111 44609.13296825648 1.0853207577173554 1.112798758866242 0.8377045707169427 1.013526589568553 0.9307309460340938 0.7981437540677787 0.9796049327405835 0.7459239620708408 0.869463156439757 1.0 15.445051487433352 -4.829293435994795 0.7243258224889993 0.8740312899346405 1.2581683200382117 0.38545909157513636 0.0910148341389291 2.6451594267051597 1.1010768218346525 0.03723692763829157 0.8248771260235893 1.4815167433011391e-05 4.829293435994795 0.38413703010357114 KSAS(ph)PEVSEGHENQHGQESEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSASPEVSEGHENQHGQESEAK 22 1 O60930 O60930 RNASEH1 Ribonuclease H1 1 KS(0.147)AS(0.852)PEVSEGHENQHGQESEAK 102.59 2.3416e-05 7561200.0 17368.0 18753.0 31586.0 47615.0 54364.0 55823.0 39352.0 46934.0 47058.0 36759.0 True False 20308.059366363686 20614.6739057406 32339.13003057206 44947.28591991281 43711.76445523933 52895.54360922491 35624.293676192145 45702.03223068358 47746.134225010515 43423.11571591609 0.4676785401403169 0.47473963039885236 0.7447445789505759 1.035100433924829 1.006647352097248 1.2181425201102474 0.8203992985960379 1.052481644331482 1.099555696034725 1.0 15.406175626152724 -5.513573248319755 2.2545569592442094 1.0362861815177078 0.4593592781906849 0.8530270310325102 0.09401994412301547 0.1071579837171746 1.0709038700142053 0.02698772248110752 0.06625619251072579 3.064973695866872e-06 5.513573248319755 -0.5769269033270229 down KSASPEVS(ph)EGHENQHGQESEAK ddPTM_PC-9_Lapatinib_30min_R1 1 KSASPEVSEGHENQHGQESEAK 22 1 O60930 O60930 RNASEH1 Ribonuclease H1 1 KS(0.101)AS(0.101)PEVS(0.798)EGHENQHGQES(0.001)EAK 55.972 0.0029186 4950900.0 53489.0 34427.0 62193.0 40736.0 56920.0 58687.0 40918.0 45729.0 61081.0 37162.0 True False 52726.237051318734 34347.28639668857 57079.73161192257 43731.86133131236 53572.077509025636 56177.093816078865 43036.53382668835 47853.736281922014 54201.41456855517 43585.402184747596 1.2097223934707642 0.7880456454456708 1.3096066286133117 1.0033602798006533 1.2291289015057616 1.2888969930335448 0.9874070599203666 1.097930359322647 1.2435680721450948 1.0 15.411557401660238 -5.272993124694961 24.998450843886122 1.1459435073350936 0.9988839935258632 0.13349305600257266 0.1488777719882066 1245.4569364584866 2694754.5832126616 0.03675965820833977 0.07755221557928678 5.333433387657937e-06 5.272993124694961 -0.14705951380923044 KSCLQCRPPS(ph)PPESSVPQQQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSCLQCRPPSPPESSVPQQQVK 22 2 P41002 P41002 CCNF Cyclin-F 1 KS(0.017)CLQCRPPS(0.95)PPES(0.017)S(0.017)VPQQQVK 55.453 0.0041855 5834000.0 16868.0 13444.0 15583.0 16942.0 19249.0 16265.0 13378.0 15946.0 14423.0 13504.0 True False 19723.41924181382 14778.631471699291 15954.5578188566 15992.794666705084 15477.296630102685 15412.03476710392 12110.73899166747 15527.434396183588 14633.909089364754 15952.168302394823 1.2364099267215503 0.9264340239866103 1.0001497925809508 1.0025467612640573 0.9702315281979035 0.9661404315042353 0.7591907734479796 0.9733745345360059 0.9173617537101734 1.0 13.961464915545983 -4.759310341488455 24.999250701906153 0.9443100676995833 1.2364103009108067 0.6176406251586483 0.06849752824251402 39.06482867122218 458590.0406220898 0.017678168484568407 0.11345413342514775 1.7405626442584977e-05 4.759310341488455 0.29210023321122347 KSCLQCRPPSPPES(ph)SVPQQQVK ddPTM_PC-9_AZD4547_30min_R2 1 KSCLQCRPPSPPESSVPQQQVK 22 2 P41002 P41002 CCNF Cyclin-F 1 KS(0.002)CLQCRPPS(0.075)PPES(0.512)S(0.411)VPQQQVK 52.298 0.0081301 11910000.0 18593.0 13310.0 16244.0 27191.0 18292.0 19813.0 16655.0 19343.0 16422.0 17744.0 True False 24505.187241575124 17612.197208763864 16028.593946358944 20922.535046762263 15752.471542903346 18574.089977901956 18137.262734989796 16353.983807920979 17290.033393822538 17122.787960853253 1.4311447001270927 1.0285823341987015 0.9360972046727498 1.2219117058855211 0.9199711857039418 1.0847585113105835 1.0592470558215095 0.9551005271635704 1.009767418328817 1.0 14.063630002423475 -4.7615305398189385 9.164271819443327 1.0255647586221153 1.4337797012300626 0.686280711684695 0.08259142403308412 0.04385808038882599 54.354336584858316 0.01951577680678175 0.11125341344977477 1.731687253299821e-05 4.7615305398189385 0.40821494260794733 KSDASDMNS(ph)DTSPSCR ddPTM_PC-9_AZD4547_30min_R2 2 KSDASDMNSDTSPSCR 16 1 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 KS(0.001)DAS(0.001)DMNS(0.325)DT(0.325)S(0.325)PS(0.023)CR;KS(0.002)DAS(0.001)DMNS(0.308)DT(0.308)S(0.308)PS(0.073)CR 53.553999999999995 0.027747000000000004 41798000.0 18701.8 17242.9 26791.0 36781.0 34358.0 26405.0 25098.0 29923.0 24516.0 29186.0 True False 24648.58337839453 22816.330221712575 26435.733835071587 28301.70871078526 29587.984762249784 24753.89117581899 27331.673378731513 25299.08791213458 25811.865709594047 28164.207023526997 0.8751740589679771 0.8101179700409435 0.938628728761597 1.0048821430386234 1.0505527365827638 0.8789131238504533 0.9704400111780166 0.8982709114089724 0.9164776302074502 1.0 14.781575231942453 -5.35811048334919 5.458398074727765 0.9573994416505611 0.8434017357550958 0.4451138988204075 0.05146779524006415 0.19857946770806564 8.830356420979784 0.014156359078068313 0.030336732854314177 4.384191509330713e-06 5.35811048334919 -0.11399770589546532 KSDASDMNSDT(ph)SPSCR ddPTM_PC-9_Lapatinib_30min_R1 2 KSDASDMNSDTSPSCR 16 1 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 KSDASDMNS(0.092)DT(0.423)S(0.338)PS(0.147)CR;KSDASDMNS(0.168)DT(0.355)S(0.355)PS(0.122)CR 62.684 0.030949 21788000.0 21765.9 18747.7 24763.2 19662.5 18296.6 22775.9 18823.5 18057.4 21694.3 14533.099999999999 True False 21455.514274622798 18704.29085250525 22727.26528471632 21108.54584217717 17220.42996049963 21801.82785021607 19798.08872590715 18896.41272577968 19250.859482893302 17045.126970861493 1.2587476943586766 1.0973394850317095 1.333358520800015 1.2383918217952883 1.0102846397059886 1.2790651479150679 1.1615101934853183 1.1086108515403226 1.1294054609157498 1.0 14.057071725847488 -9.021770001209463 0.28145967092610613 0.9543946982387229 1.2319390788663287 0.34127066861857713 0.08727037074577866 4.51005421054818 0.7760418767340944 0.38664417205612844 0.13908702815798035 9.51108359477599e-10 9.021770001209463 0.2775443806276058 KSDASDMNSDTS(ph)PSCR ddPTM_PC-9_AZD4547_30min_R2 2 KSDASDMNSDTSPSCR 16 1 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 KSDASDMNS(0.025)DT(0.197)S(0.581)PS(0.197)CR;KSDASDMNS(0.004)DT(0.096)S(0.655)PS(0.244)CR 75.608 0.0055816 8479100.0 19669.5 16292.4 31516.0 46909.0 40034.0 37184.0 22227.6 35461.0 25129.0 32020.0 True False 25923.991848984126 21558.599684753142 31098.077247811416 36094.85478682545 34475.97013714149 34858.878601842574 24205.813339433145 29981.317262714434 26457.26763812973 30898.989546129458 0.8389915731801488 0.6977121259116924 1.0064431783888834 1.168156477510018 1.1157636752383737 1.1281559401740744 0.7833852723014132 0.9703008966670247 0.8562502537059139 1.0 14.915272039665384 -5.2730341804095735 23.522170552276297 1.0089689297269375 0.7683518586930267 0.39234800474747755 0.11692916969356823 311.33905112238307 631610.3849998456 0.033312186622007245 0.07042479399859077 5.332929219222616e-06 5.2730341804095735 -0.24061707103391083 KSDASDMNSDTS(ph)PSCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSDASDMNSDTSPSCR 16 1 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 KSDASDMNS(0.021)DT(0.187)S(0.792)PSCR 103.04 0.0082043 0.0 4752.3 5063.2 4877.9 5851.7 6919.0 6614.4 6315.9 7962.8 6801.4 5364.0 True False 5556.770527796531 5565.841034476931 4994.207635538768 5523.848220467371 5563.271618457087 6267.52922001428 5717.612228843817 7753.784937284002 6900.857608015358 6336.450738599365 0.8769531646394243 0.8783846452986436 0.7881711452621043 0.8717574630254894 0.8779791476271803 0.9891230088533255 0.9023367283539653 1.2236795103685965 1.0890730304234564 1.0 12.629459248743272 -7.302332650808536 1.3471913202450487 1.1071881360479265 0.8566185717321995 0.6218422448473884 0.07493900682326385 0.2653671978286646 0.9344113560162778 0.04640089856056808 0.026063332539663156 4.9850250980583103e-08 7.302332650808536 -0.2505695643157271 KSDASDMNSDTS(ph)PSCR ddPTM_PC-9_Lapatinib_30min_R1 3 KSDASDMNSDTSPSCR 16 1 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 KSDASDMNS(0.011)DT(0.233)S(0.756)PSCR;KSDASDMNS(0.003)DT(0.244)S(0.735)PS(0.018)CR;KSDASDMNS(0.043)DT(0.233)S(0.668)PS(0.056)CR 140.68 3.1836e-05 21579600.0 98841.0 77577.4 101065.0 91182.0 96584.0 89255.4 78192.2 79247.6 105521.0 69475.5 True False 97431.50921478056 77397.77429664138 92755.82582218207 97887.82845423506 90903.11901145002 85438.15460649955 82240.60951862705 82929.73280358722 93636.11379460891 81484.24760471545 1.1957097485568762 0.949849530084664 1.1383283094438776 1.2013098400207889 1.1155913159120772 1.0485235750223125 1.009282308374261 1.0177394434060911 1.1491314769063443 1.0 16.314233566511767 -6.770804366329299 6.560189032605038 1.0435020969442432 1.1163815722220476 0.19918506959047 0.07524220199349405 0.27629083539473615 51.04589978719574 0.02653620537573271 0.024519048051992075 1.695101209161327e-07 6.770804366329299 0.07287947527780436 KSDGIYIINLK ddPTM_PC-9_Lapatinib_30min_R1 1 KSDGIYIINLK 11 1 C9J9K3;A0A0C4DG17;P08865;F8WD59 C9J9K3 RPSA 40S ribosomal protein SA 0 83.045 0.038139 0.0 36769.0 31161.0 38407.0 30466.0 33433.0 32274.0 38921.0 32054.0 35720.0 32722.0 False True 36244.66731739123 31088.84861902614 35249.32471530737 32706.571271596673 31466.53667180699 30893.716254368588 40936.13893808438 33543.34585888012 31696.83745172459 38377.95410067572 0.9444137439508029 0.8100705039531734 0.9184784739394624 0.8522228982242909 0.8199117803221553 0.804986012889745 1.0666576657707665 0.8740264207645588 0.8259126416321005 1.0 15.227990184165549 KSDIDEIVLVGGSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSDIDEIVLVGGSTR 15 1 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 121.32 4.2791000000000004e-05 4841800.0 44729.0 49150.0 45595.0 52160.0 69457.0 59535.0 48041.0 67002.0 48892.0 44007.0 False True 52300.73626198071 54029.2871789661 46682.157720000425 49237.64430500165 55847.39945124647 56412.87979462234 43490.20869327981 65243.26849448714 49606.95300542343 51985.12074077967 1.0060712664836318 1.0393221446648078 0.8979907530229253 0.947148791873003 1.074295849570607 1.0851735841092185 0.8365895485775792 1.255037356166168 0.9542529150366926 1.0 15.665811131548468 -6.2562995725029875 24.507820723410333 1.0396424120443297 0.972065127032042 0.07409770848690578 0.1056172554210471 881.3073217518182 4202272.69029178 0.030725219591604902 0.038441068055034916 5.542432689515208e-07 6.2562995725029875 -0.06757728501228777 KSDIDEIVLVGGSTR ddPTM_PC-9_Lapatinib_30min_R1 1 KSDIDEIVLVGGSTR 15 1 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 92.264 0.002307 10055000.0 70566.0 67978.0 79674.0 64534.0 71348.0 76565.0 72141.0 70238.0 74366.0 60454.0 False True 69559.71589978042 67820.60111755595 73123.51127053381 69280.04563911317 67151.45091556513 73290.49343173235 75876.10799137603 73501.5138964253 65990.1179713033 70903.39335010854 0.9810491799215691 0.9565212313981886 1.0313118712028735 0.9771047952108645 0.9470837394760928 1.033666937065152 1.0701336622453752 1.0366431058311651 0.9307046511223469 1.0 16.113567054295252 -6.780063717325312 24.999800159627473 1.0200138683620894 0.9802305659737811 0.16059737018205922 0.039537592454587475 435.3961548424765 584436.9604352583 0.014382350332322663 0.01270534795519433 1.6593434397295287e-07 6.780063717325312 -0.039783302388308295 KSDVEAIFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSDVEAIFSK 10 1 B4DY08;B2R5W2;G3V4W0;G3V576;G3V555;G3V575;G3V5X6;G3V3K6;G3V251;B4DSU6;B7ZW38;P0DMR1;A0A0G2JPF8;G3V4M8;G3V2H6;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;A0A0G2JNQ3;B2RXH8;O60812 B4DY08;P07910-2;A0A0G2JNQ3 HNRNPC;HNRNPCL3;HNRNPCL4;HNRNPCL2;HNRNPCL1 Heterogeneous nuclear ribonucleoprotein C-like 3;Heterogeneous nuclear ribonucleoprotein C-like 4;Heterogeneous nuclear ribonucleoproteins C1/C2;Heterogeneous nuclear ribonucleoprotein C-like 2;Heterogeneous nuclear ribonucleoprotein C-like 1 0 66.267 0.029518 4343200.0 44518.0 42901.0 44649.0 55058.0 54000.0 42238.0 50468.0 42993.0 38736.0 39480.0 False True 52054.018129420714 47159.92775716836 45713.60149227544 51973.278760444424 43419.087642243474 40022.964924250584 45687.305683321436 41864.47930484891 39302.44071868776 46637.41147649193 1.1161429522232185 1.0112038010715885 0.9801916539754325 1.1144117375948726 0.9309926573461161 0.8581729486514185 0.9796278188885033 0.8976587246046264 0.842723459008838 1.0 15.509200096182557 -6.384431193850807 6.360224734565748 0.9114447151345269 1.046467382732814 0.5591492564434819 0.05952386495083676 0.1843745781205642 8.824649121931829 0.018205848740696896 0.02064225667168257 4.126376069451354e-07 6.384431193850807 0.13502266759828707 KSDVEAIFSK ddPTM_PC-9_Lapatinib_30min_R1 2 KSDVEAIFSK 10 1 B4DY08;B2R5W2;G3V4W0;G3V576;G3V555;G3V575;G3V5X6;G3V3K6;G3V251;B4DSU6;B7ZW38;P0DMR1;A0A0G2JPF8;G3V4M8;G3V2H6;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;A0A0G2JNQ3;B2RXH8;O60812 B4DY08;P07910-2;A0A0G2JNQ3 HNRNPC;HNRNPCL3;HNRNPCL4;HNRNPCL2;HNRNPCL1 Heterogeneous nuclear ribonucleoprotein C-like 3;Heterogeneous nuclear ribonucleoprotein C-like 4;Heterogeneous nuclear ribonucleoproteins C1/C2;Heterogeneous nuclear ribonucleoprotein C-like 2;Heterogeneous nuclear ribonucleoprotein C-like 1 0 ; 119.39 0.00050239 19724900.0 302520.0 280380.0 284780.0 276690.0 267450.0 267400.0 260300.0 219070.0 264680.0 276070.0 False True 298206.00932462665 279730.7973364963 261366.48768259044 297038.7056107821 251719.11682693096 255963.9253398452 273777.06034231844 229248.7919543535 234868.95119603802 323788.3316598481 0.9209905983823511 0.8639310623162421 0.8072140411692347 0.9173854539107743 0.777418740003798 0.7905285654603051 0.8455433181882898 0.7080205478040142 0.725378057918334 1.0 18.304691470701783 -6.275564206109846 24.445567333596095 0.7942380027295037 0.8714077567366116 0.1353993385477128 0.08135795505746513 1043.2190785198736 1805475.3181762525 0.0243478915264829 0.027752859836210956 5.301952027593474e-07 6.275564206109846 0.0771697540071079 KSEAAVGAEVSMT(ph)S(ph)PGQS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSEAAVGAEVSMTSPGQSK 19 1 A0A0A0MTH5;Q9NR20-5;Q9NR20-2;Q9NR20;Q9NR20-3;Q9NR20-4 A0A0A0MTH5 DYRK4 Dual specificity tyrosine-phosphorylation-regulated kinase 4 3 KS(0.002)EAAVGAEVS(0.034)MT(0.988)S(0.988)PGQS(0.989)K 42.611999999999995 0.043197 0.0 4906.8 10176.0 7293.3 8665.3 6930.6 6306.6 9348.4 9347.6 5384.1 4266.7 True False 5737.424326282432 11186.206029158873 7467.199931994281 8179.811334281644 5572.598681728386 5975.870793865211 8462.851875445074 9102.235404600884 5462.832276783529 5040.218934821386 1.1383283941584879 2.219388914214951 1.4815229315547385 1.622907941115363 1.1056263138152482 1.1856371461524584 1.6790643392448148 1.805920640017485 1.0838482112438474 1.0 12.299270686903347 -12.732063938454134 0.13404792010898184 2.5654569187841916e-11 1.732234446519399 0.17286873220606458 0.3428376370142127 148.5880169184142 1.9797987911996326 45.390694398344955 2.7195943507643667 1.8532587596595247e-13 12.732063938454134 1.7322344464937445 KSEAPAEVTHFS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 KSEAPAEVTHFSPK 14 1 Q6PID6 Q6PID6 TTC33 Tetratricopeptide repeat protein 33 1 KSEAPAEVT(0.003)HFS(0.997)PK 57.498999999999995 0.024536000000000002 7564000.0 93575.0 74110.0 75989.0 62579.0 87898.0 80672.0 79128.0 77408.0 76328.0 67635.0 True False 92240.60334044675 73938.40284830474 69741.47774602268 67181.26841742435 82728.01245411686 77221.84661561706 83224.86066372239 81004.65827179738 67731.13687052733 79325.61963202753 1.1628097425312114 0.9320873028321394 0.8791797412933755 0.8469050570176708 1.0428914748838043 0.973479274083589 1.0491548764419678 1.0211664106446128 0.8538368459611886 1.0 16.275499264984035 -4.757270656037195 24.802952733915518 0.9565274859688038 1.1628100783201911 0.428882869030878 0.07178888178525349 117.44239409273416 698652.9487696451 0.018925533793302748 0.14175291202033738 1.7487565089355517e-05 4.757270656037195 0.20628259235138735 KSEEEIDFLR ddPTM_PC-9_AZD4547_30min_R2 1 KSEEEIDFLR 10 1 B0QY90;B0QY89;Q9Y262-2;Q9Y262 B0QY90 EIF3L Eukaryotic translation initiation factor 3 subunit L 0 79.48899999999999 0.011994 5575100.0 31318.0 22434.0 33777.0 45495.0 38857.0 39083.0 34890.0 36122.0 27155.0 36838.0 False True 41276.47254513259 29685.35177921928 33329.09491050027 35006.830640743196 33462.376270642635 36639.133831642976 37995.14240911402 30540.174900983362 28590.35786196875 35548.31283261454 1.1611373158408416 0.8350706239983304 0.9375717792131558 0.9847677105121414 0.9413210812059098 1.0306855913011894 1.0688311028436372 0.8591174226688937 0.8042676454601787 1.0 15.11749346890803 -7.786835825197034 24.979863466727622 0.873769307736393 0.9849066460175674 0.20463355415934636 0.09368392913412069 350.5540338888138 344798.68025093514 0.049901059487346515 0.023986055464470604 1.6336694014308525e-08 7.786835825197034 0.11113733828117434 KSEEEIDFLR ddPTM_PC-9_Lapatinib_30min_R1 1 KSEEEIDFLR 10 1 B0QY90;B0QY89;Q9Y262-2;Q9Y262 B0QY90 EIF3L Eukaryotic translation initiation factor 3 subunit L 0 97.59700000000001 0.0032169000000000004 9660900.0 28745.0 37067.0 39648.0 37180.0 32053.0 38058.0 40826.0 37035.0 37452.0 27059.0 False True 28335.091028812596 36981.173638889675 36388.29448570591 39914.34122884411 30167.70555862263 36430.348057531104 42939.77051684779 38755.781302914584 33233.761372956054 31736.11209614887 0.8928343504386291 1.165271080680903 1.1465895499569267 1.2576947392899982 0.9505797517737983 1.1479146515225434 1.3530255497824029 1.2211886946169925 1.0471906978482384 1.0 14.953837777944136 -6.993813779614794 24.986121204450743 1.1847388484715078 1.0953479151826178 0.045317363374091424 0.13361809441250008 420.90633157947985 1700024.8300430456 0.047194148812205496 0.04151313644546876 1.0143462322807585e-07 6.993813779614794 -0.08939093328889003 KSKS(ph)PPKVPIVIQDDSLPAGPPPQIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSKSPPKVPIVIQDDSLPAGPPPQIR 26 3 Q7Z422-4;Q7Z422-5;Q7Z422 Q7Z422-4 SZRD1 SUZ domain-containing protein 1 1 KS(0.254)KS(0.743)PPKVPIVIQDDS(0.003)LPAGPPPQIR 49.871 0.019132 4396700.0 15878.0 10715.0 14698.0 23307.0 19956.0 25085.0 19705.0 17414.0 18550.0 15450.0 True False 18565.831795205133 11778.714387031972 15048.456062475405 22001.184352313518 16045.765055344646 23769.49844038133 17838.39974815426 16956.900951658154 18821.258656847825 18250.9626978673 1.0172521911611065 0.6453749636126517 0.8245294405337795 1.2054807582771754 0.879173626124372 1.3023695699711715 0.9773950034010398 0.929096247270268 1.031247445322277 1.0 14.155684944517898 -5.660232927053017 8.984312300461697 1.0440501336948862 0.8079942002505006 0.31818448177803405 0.14493053356641308 0.2953186507933405 23.749397717771124 0.03781993066062398 0.06557810183251095 2.1865885668226094e-06 5.660232927053017 -0.23605593344438558 KSLGKDS(ph)ILS(ph)NAGS(ph)SPNGFSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSLGKDSILSNAGSSPNGFSEK 22 2 F5H269;Q9Y485 F5H269 DMXL1 DmX-like protein 1 3 KS(0.241)LGKDS(0.89)ILS(0.869)NAGS(0.754)S(0.145)PNGFS(0.101)EK 51.956 0.035199 0.0 13370.0 17990.0 9637.3 19127.0 14859.0 12637.0 14827.0 15928.0 11699.0 6678.1 True False 15633.27693046306 19775.928308231934 9867.089781663779 18055.376200570663 11947.485616223998 11974.29347383291 13422.479221815933 15509.906877110998 11870.075742666457 7888.786666189485 1.9817086697838655 2.506840296872204 1.2507740669364396 2.2887393162695244 1.5144896321546724 1.5178878553217163 1.7014630753476039 1.9660700096739638 1.5046769858209452 1.0 12.945587708439486 -8.799836236500088 0.08152780723044593 1.3303750384851861e-17 2.9789883925857157 0.3897070173996171 0.34407793115082946 31.686131142862784 1.3593576429916165 27.541713400861493 20.163300906101718 1.5854909357164143e-09 8.799836236500088 2.9789883925857157 KSLS(ph)DSESDDSK ddPTM_PC-9_AZD4547_30min_R2 2 KSLSDSESDDSK 12 1 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 KS(0.163)LS(0.781)DS(0.032)ES(0.023)DDS(0.001)K;KS(0.033)LS(0.94)DS(0.006)ES(0.001)DDS(0.02)K 130.47 0.00021312 18941000.0 51022.0 52316.0 45000.0 48927.0 54832.0 56594.0 50469.0 51939.0 49136.0 57889.0 True False 67245.93467647216 69226.12390486017 44403.2705975223 37647.636064614635 47219.523269214726 53055.16823345197 54960.64322859199 43913.02098948493 51733.228646867865 55862.32373004024 1.2037797604239353 1.239227430627514 0.7948697374657228 0.6739360905670566 0.8452839072253308 0.9497486801631435 0.9838588794514581 0.7860937042593967 0.9260844374622401 1.0 15.76958796684576 -5.256701789132268 24.989073248648275 0.8613766961254992 1.221503639142041 0.6810145128561246 0.09608691487539385 221.83738111714038 1170101.7727716137 0.026249173922838466 0.06485928116359659 5.537302008133603e-06 5.256701789132268 0.3601269430165419 KSLS(ph)DSESDDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 KSLSDSESDDSK 12 1 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 KS(0.1)LS(0.67)DS(0.217)ES(0.011)DDS(0.001)K;KS(0.01)LS(0.959)DS(0.025)ES(0.007)DDSK;KS(0.25)LS(0.736)DS(0.013)ES(0.001)DDSK;KS(0.143)LS(0.857)DSESDDSK;KSLS(0.998)DS(0.002)ESDDSK;KS(0.001)LS(0.992)DS(0.004)ES(0.002)DDSK;KSLS(0.999)DSESDDSK 177.39 2.0591e-05 127732000.0 368075.0 368290.9 310209.19999999995 411751.5 443156.1 346272.5 417831.1 379698.4 361532.8 310255.89999999997 True False 430382.82768737385 404852.38660223637 317605.76380294235 388682.3983713739 356322.84342768166 328113.36052210245 378251.1133727995 369731.7193237093 366819.53324713913 366502.83868564654 1.1742960279129457 1.1046364280672942 0.8665847308084734 1.0605167473334387 0.972223966137691 0.8952546225802328 1.032055071467617 1.008809974431964 1.0008640985227517 1.0 18.4834648469892 -5.04947290040097 7.083932510396203 0.9812861060437643 1.1581049818514892 0.5792214810993086 0.05591811620213702 0.13716998300904362 16.98746259995736 0.01389459899868052 0.038602889427419906 8.923332986746082e-06 5.04947290040097 0.17681887580772493 KSLS(ph)DSESDDSK ddPTM_PC-9_Lapatinib_30min_R1 4 KSLSDSESDDSK 12 1 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 KS(0.016)LS(0.983)DS(0.001)ESDDSK;KS(0.152)LS(0.801)DS(0.046)ES(0.001)DDSK;KS(0.014)LS(0.985)DS(0.001)ES(0.001)DDSK;KS(0.052)LS(0.813)DS(0.007)ES(0.117)DDS(0.011)K 143.97 9.6816e-05 195839000.0 71420.2 82267.5 74339.6 79070.2 93864.6 86207.0 77171.0 82189.0 76486.3 71428.0 True False 70401.73485113942 82077.01465825006 68227.6850471545 84885.28627845489 88343.66877290394 82520.12756833225 81166.53677939699 86007.8009856958 67871.60745755435 83774.23462817242 0.8403745514789107 0.9797405493770802 0.8144232573413477 1.0132624506235577 1.0545446241915872 0.9850299192179259 0.9688723166454513 1.0266617339738995 0.8101728145747789 1.0 16.354218980398066 -5.778961365857502 24.999497954921345 0.9837808475781497 0.8883355341536159 0.28078818810989026 0.0737971961598796 313.16294638589903 446804.29884578526 0.02026627875318787 0.03013648036310611 1.663560631481061e-06 5.778961365857502 -0.09544531342453377 KSLS(ph)DSESDDSKSK ddPTM_PC-9_Lapatinib_30min_R1 1 KSLSDSESDDSKSK 14 2 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 KS(0.017)LS(0.86)DS(0.121)ES(0.001)DDSKSK 80.382 0.032792 16039000.0 117400.0 26184.0 21954.0 25181.0 21714.0 22072.0 12086.0 13188.0 28446.0 14376.0 True False 115725.85447147694 26123.372556740153 20149.026864890722 27032.894741353513 20436.825211366544 21128.032012345033 12711.753942747822 13800.762625161005 25242.11193034037 16860.87244518409 6.8635745183240084 1.549348803964274 1.1950168611023337 1.60329157516845 1.2120858679055981 1.253080591234753 0.7539202958847265 0.8185082159910929 1.4970821950290112 1.0 14.041391568247935 -4.760210606260029 4.8261076065775566 1.176421455772803 7.271390440720546 0.9786427716782944 0.25115442858417836 0.025245725135376137 1.451080231078272 0.0678396153679024 0.5285091599720215 1.7369583059428347e-05 4.760210606260029 6.094968984947743 up KSMS(ph)EDGGLQESNPCADDFVSASTADVSHTNLGTIR ddPTM_PC-9_AZD4547_30min_R2 1 KSMSEDGGLQESNPCADDFVSASTADVSHTNLGTIR 36 1 A0A1W2PRP5;H7C0I1;B8ZZW5;Q8NBF6-2;Q8NBF6 A0A1W2PRP5 AVL9 Late secretory pathway protein AVL9 homolog 1 KS(0.179)MS(0.802)EDGGLQES(0.019)NPCADDFVSASTADVSHTNLGTIR 91.74799999999999 4.4967e-13 11443000.0 25847.0 23880.0 58240.0 71532.0 58483.0 59986.0 46407.0 63547.0 48115.0 49372.0 True False 34065.80834900188 31598.743001148083 57467.69954665999 55041.40255838325 50363.644940062084 56235.06593723448 50537.13309772864 53727.27131478848 50658.26067128067 47643.50130766725 0.7150147955964707 0.663233014658033 1.2062022724894013 1.1552761876786217 1.0570936970989806 1.1803302526841073 1.060735078460653 1.127693595981414 1.0632774519266546 1.0 15.539991819904994 -5.255765164407621 24.993532520719675 1.1118912318626226 0.6891238526924449 0.8810828982107732 0.06128116543373008 127.21031543683681 560326.2509678847 0.014971767951452133 0.03737262700302217 5.549256962261299e-06 5.255765164407621 -0.4227673791701777 KSMSLDMGQPS(ph)QANTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSMSLDMGQPSQANTK 16 1 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 KS(0.066)MS(0.066)LDMGQPS(0.765)QANT(0.104)K 43.05 0.045936000000000005 7189700.0 50097.0 35652.0 28735.0 39795.0 35167.0 28683.0 23954.0 29946.0 13494.0 22045.0 True False 58577.43263914796 39191.29494414037 29420.15137809434 37565.41516713073 28276.27879842178 27178.8129864643 21684.903708058202 29159.949230409733 13691.32422186008 26041.583991876018 2.2493805544786327 1.5049505036393547 1.1297373995096576 1.4425165219922764 1.0858125530014957 1.0436697320310107 0.8327029459814375 1.1197456053175001 0.5257485192195395 1.0 14.668529583341908 -1.5228787452804151 0.4754722012886479 0.8998669079025113 35.35479797284618 0.8079032245013036 0.19259545122287738 40.68888945131745 0.4612826364679336 0.11091538983899736 1382.0629412221786 0.029999999999994642 1.5228787452804151 34.454931064943665 up KSNLDEEVNVIPPHT(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 6 KSNLDEEVNVIPPHTPVR 18 1 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 KSNLDEEVNVIPPHT(1)PVR;KSNLDEEVNVIPPHT(1)PVR;KSNLDEEVNVIPPHT(1)PVR;KSNLDEEVNVIPPHT(1)PVR;KSNLDEEVNVIPPHT(1)PVR;KSNLDEEVNVIPPHT(1)PVR 145.72 0.00013641 274921000.0 947831.0 867926.0 1302073.0 1665783.0 1459908.0 1214835.0 1185691.0 1376519.0 1133960.0 1335000.0 True False 1249221.5418904624 1148466.106282013 1284806.6612606137 1281762.4654407983 1257224.9740464082 1138871.1754052648 1291215.2020121773 1163809.617809829 1193898.810574777 1288262.056342372 0.9696952073844717 0.8914848501730563 0.9973177855664175 0.9949547602760053 0.9759077882150127 0.8840368850408766 1.002292348560036 0.9033950911463715 0.9267515135581105 1.0 20.296994663498765 -7.784075642022909 24.995597728399034 0.9363050324728799 0.9573373772263969 0.0171927783265855 0.0452470248388223 949.49507781215 1048443.9755718837 0.02440045930977566 0.011735581289412864 1.6440853443239087e-08 7.784075642022909 0.021032344753517007 KSNLDEEVNVIPPHT(ph)PVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 KSNLDEEVNVIPPHTPVR 18 1 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 KSNLDEEVNVIPPHT(1)PVR;KSNLDEEVNVIPPHT(1)PVR;KSNLDEEVNVIPPHT(1)PVR;KSNLDEEVNVIPPHT(1)PVR;KSNLDEEVNVIPPHT(1)PVR;KSNLDEEVNVIPPHT(1)PVR 137.43 8.759299999999999e-05 153206600.0 1072832.0 993104.0 1186261.0 1412446.0 1451147.0 1335346.0 1336383.0 1338572.0 1279497.0 1037271.0 True False 1254441.268202136 1091692.801924314 1214545.9611598959 1333311.2298317137 1166805.1624958992 1265318.1050177168 1209791.1276649379 1303435.9033342681 1298207.2230544935 1225320.0212672797 1.0237662377414987 0.8909450453565896 0.9912071459533969 1.0881330645791167 0.9522452438907659 1.0326429692294339 0.9873266629673763 1.063751412456476 1.0594842167940997 1.0 20.22472716165325 -5.521190702426377 24.996198229949762 1.0256175873349587 0.9532857489440063 0.2512941449743348 0.04787326725046947 73.6641771673649 1090798.6419140794 0.012383004024565708 0.021868058423325076 3.0116832778728638e-06 5.521190702426377 -0.07233183839095236 KSNLDEEVNVIPPHT(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 7 KSNLDEEVNVIPPHTPVR 18 1 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 KSNLDEEVNVIPPHT(1)PVR;KSNLDEEVNVIPPHT(1)PVR;KSNLDEEVNVIPPHT(1)PVR;KSNLDEEVNVIPPHT(1)PVR;KSNLDEEVNVIPPHT(1)PVR;KSNLDEEVNVIPPHT(1)PVR;KSNLDEEVNVIPPHT(1)PVR 153.6 8.3422e-06 344860000.0 2157870.0 1843380.0 2139180.0 1823290.0 1861049.0 1832812.0 1563511.0 1457686.0 2069300.0 1392784.0 True False 2127098.378095107 1839111.766866933 1963304.8778735918 1957380.82891714 1751585.7567831103 1754426.9032534463 1644461.9492619236 1525415.4131043695 1836233.6433049752 1633524.8586319739 1.3021524385472074 1.125854777874107 1.2018824614140238 1.1982559179150694 1.072273707698583 1.0740129811815193 1.0066953928323499 0.9338183040458028 1.1240928680098348 1.0 20.639556978891818 -6.450775380861509 1.3455003121321656 1.0134901488283388 1.2099443317811465 0.663654459422234 0.060760311430433436 0.256982659165076 0.9546453688172707 0.02450289937776079 0.02916449129372535 3.5418047752034075e-07 6.450775380861509 0.1964541829528077 KSPS(ph)SDSWTCADTSTER ddPTM_PC-9_Lapatinib_30min_R1 2 KSPSSDSWTCADTSTER 17 1 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHH7;H0YIQ0 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 KS(0.019)PS(0.923)S(0.051)DS(0.007)WTCADTSTER;KS(0.161)PS(0.461)S(0.347)DS(0.028)WT(0.001)CADTS(0.001)T(0.002)ER 105.39 0.0010655999999999999 11344800.0 21730.0 22264.0 24908.0 16502.0 28894.0 25150.0 29289.0 25063.0 24402.0 18642.2 True False 21420.12621520606 22212.449075896075 22860.160387660475 17715.61212905824 27194.511727789668 24074.393127513475 30805.44110782237 26227.51847697984 21653.589795548254 21864.479430829913 0.9796769359622943 1.015914837861427 1.0455387451588078 0.8102462345423336 1.2437758609264744 1.101073236327204 1.408926345823962 1.1995491847840585 0.9903546921412502 1.0 14.416301379397769 -6.279048525957035 24.986408169180596 1.177029340561906 0.9725416902736437 0.3488394617134428 0.12817767346136286 881.5205159195172 1250826.1021090196 0.039741977167276545 0.0451608126589242 5.259584950584929e-07 6.279048525957035 -0.2044876502882622 KSPSLESLS(ph)RPPSLGFGDTR ddPTM_PC-9_AZD4547_30min_R2 1 KSPSLESLSRPPSLGFGDTR 20 2 Q5M775;Q5M775-4;J3KSG2 Q5M775 SPECC1 Cytospin-B 1 KS(0.007)PS(0.079)LES(0.226)LS(0.686)RPPS(0.002)LGFGDT(0.001)R 73.459 0.0079732 53658000.0 52521.0 50023.0 60316.0 96132.0 87818.0 77366.0 66382.0 91845.0 70340.0 76561.0 True False 69221.58549533528 66191.95649691924 59516.170430225684 73970.25262459443 75625.98654902074 72528.29178975231 72289.86940102615 77652.46563813795 74058.02879804384 73880.62269335469 0.9369383063085841 0.8959312209867579 0.805572127853478 1.001213172385021 1.0236241086233162 0.9816957294849112 0.9784685992844019 1.0510532099930787 1.0024012535117022 1.0 16.1729084054912 -5.8264120154624575 10.522196358474593 1.0064221363786399 0.8812225662884922 0.7224740402209359 0.03578421569485836 0.2289191948295623 35.78420599362523 0.010259206485291118 0.01523863583058045 1.4913788661041772e-06 5.8264120154624575 -0.1251995700901477 KSPVGKS(ph)PPSTGSTYGSSQK ddPTM_PC-9_AZD4547_30min_R2 1 KSPVGKSPPSTGSTYGSSQK 20 2 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 KS(0.06)PVGKS(0.817)PPS(0.092)T(0.028)GS(0.003)TYGSSQK 81.878 0.00037501 17191000.0 174980.0 177480.0 213230.0 220610.0 236760.0 228960.0 210090.0 232680.0 228730.0 185520.0 True False 230620.0001898999 234846.93918943714 210402.43087799323 169751.77289052348 203889.9607750821 214643.09500532155 228787.6030017412 196724.652454482 240820.20083845 179025.00126789344 1.2881999640083766 1.3118108505862351 1.1752684227782606 0.9482014896707445 1.1388909891416823 1.1989559753396068 1.2779645378099056 1.0988669239560722 1.3451763671716783 1.0 17.449801551795133 -11.782376986467824 2.4728567006986317 0.1620529370358168 1.1911754613714276 0.21714287487272776 0.11216939461711503 7536312.123172474 3097366.576994855 37157927.964392066 0.03030807631648556 1.6505284458542517e-12 11.782376986467824 1.0291225243356108 KSPVGKS(ph)PPSTGSTYGSSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSPVGKSPPSTGSTYGSSQK 20 2 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 KS(0.174)PVGKS(0.704)PPS(0.072)T(0.03)GS(0.01)T(0.004)Y(0.004)GS(0.003)SQK 45.571999999999996 0.026121 14927000.0 48440.0 57029.0 61269.0 69680.0 71466.0 49443.0 67865.0 47642.0 51850.0 51907.0 True False 56639.93526638972 62690.462228469114 62729.88532397642 65776.0555056079 57462.75032297359 46850.122040572984 61436.33589994862 46391.447980871584 52608.208159437214 61317.32820441407 0.9237182526539434 1.022393898499253 1.0230368341368903 1.072715616152252 0.9371372172546324 0.764060069355735 1.001940849332799 0.7565797359306987 0.8579664134101995 1.0 15.904007214996575 -6.521971440979774 24.988300415711148 0.8667421608730397 1.011304844194238 0.3601217652481121 0.08396190995008262 33.05287973460824 910355.7881550265 0.026197673964321346 0.026514354380674805 3.006273987425795e-07 6.521971440979774 0.14456268332119837 KSPVGKS(ph)PPSTGSTYGSSQK ddPTM_PC-9_Lapatinib_30min_R1 1 KSPVGKSPPSTGSTYGSSQK 20 2 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 KS(0.23)PVGKS(0.71)PPS(0.04)T(0.015)GS(0.002)T(0.002)YGSSQK 69.986 0.0014049000000000002 12227000.0 63017.0 81001.0 85233.0 92152.0 85820.0 91461.0 73391.0 91626.0 87583.0 73531.0 True False 62118.36602409755 80813.44716118641 78225.47174889452 98929.16549006058 80772.23632861172 87549.42623600436 77190.82687507913 95883.27845715801 77718.480250123 86240.73537610112 0.7202903100628207 0.9370681593652238 0.9070594239224474 1.1471280371001527 0.9365903012811644 1.0151748573826043 0.8950622526401847 1.111809611073064 0.9011806301417533 1.0 16.396081859575524 -4.443481511028116 1.4334420647544523 0.9961133635768005 0.3633409536701199 0.49638963536725755 0.08142168164676188 2.2195887063984876 2.2195763691720263 0.021752833877390392 2.5479230485924376 3.601790837675432e-05 4.443481511028116 -0.6327724099066805 KSS(ph)ADTEFSDECTTAER ddPTM_PC-9_AZD4547_30min_R2 2 KSSADTEFSDECTTAER 17 1 Q9H6S0 Q9H6S0 YTHDC2 Probable ATP-dependent RNA helicase YTHDC2 1 KS(0.325)S(0.675)ADTEFSDECTTAER;KS(0.304)S(0.695)ADTEFSDECTTAER 197.38 4.3678e-12 15742900.0 26275.0 32875.0 32490.0 43425.0 37070.0 35563.0 33723.0 39538.0 33215.0 28365.0 True False 34629.903446048855 43501.20084433597 32059.16137141113 33414.03715956201 31923.470374777335 33339.239988095054 36724.28166989255 33428.31059285425 34970.677090233556 27371.949983634047 1.265160263216702 1.5892620317641144 1.171241412854386 1.2207401072828419 1.1662841117956406 1.2180074860588634 1.341675755357231 1.2212615693380033 1.2776100026173824 1.0 14.740410595820045 -14.522878745280336 0.09224915075442995 0.2124123499823445 1.4705919182075196 0.348497606099497 0.11495384617375637 252.47985864097254 1.6049735361974564 39.96630610739694 2.611698169606045 3.0000000000000132e-15 14.522878745280336 1.258179568225175 KSS(ph)ADTEFSDECTTAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSSADTEFSDECTTAER 17 1 Q9H6S0 Q9H6S0 YTHDC2 Probable ATP-dependent RNA helicase YTHDC2 1 KS(0.221)S(0.779)ADTEFSDECTTAER 76.015 0.003941 7052400.0 10768.0 11091.0 12482.0 12929.0 15597.0 18194.0 15351.0 16463.0 18618.0 13470.0 True False 12590.809722305625 12192.041182134548 12779.61821824861 12204.630046383554 12540.879814001328 17239.874611293508 13896.84214838446 16030.863693990364 18890.253028204468 15912.004371538673 0.7912774172452108 0.766216555592587 0.8031432068424473 0.7670077107453296 0.7881395405114912 1.0834508468417692 0.8733558528453729 1.007469789454325 1.1871699244875082 1.0 13.957827957188464 -6.751216673302303 24.99669005827497 1.020947802547596 0.7824288739528672 0.7346838750170844 0.0741491277700627 113.64195004920352 277878.34791989706 0.02499989338942048 0.02473158308816285 1.773304543064386e-07 6.751216673302303 -0.23851892859472879 KSS(ph)ADTEFSDECTTAER ddPTM_PC-9_Lapatinib_30min_R1 1 KSSADTEFSDECTTAER 17 1 Q9H6S0 Q9H6S0 YTHDC2 Probable ATP-dependent RNA helicase YTHDC2 1 KS(0.046)S(0.949)ADT(0.005)EFSDECTTAER 56.766000000000005 0.021908 7338200.0 7617.0 9783.3 10458.0 7720.7 10779.0 10357.0 12747.0 15180.0 18402.0 13075.0 True False 7508.380183213275 9760.647369934162 9598.183609047424 8288.506033500189 10145.00041232937 9914.055253346205 13406.97728844999 15885.318217314523 16329.372978349274 15334.996328657619 0.4896238657182996 0.6364949270769458 0.6259006134295972 0.540496121150734 0.6615587115186113 0.6464987040667947 0.8742732636587204 1.0358866658238761 1.0648436183733148 1.0 13.904540200759659 -7.390146136752979 1.7297104583522078 1.0484400669607963 0.5904926607738414 0.9437171825907902 0.04843046412060965 0.07705136556396436 0.4485420372913672 0.027848410918253866 0.015382135318471329 4.0724322053446606e-08 7.390146136752979 -0.45794740618695484 KSS(ph)GTGTEPVAK ddPTM_PC-9_AZD4547_30min_R2 2 KSSGTGTEPVAK 12 1 B8ZZI9;Q6ULP2-7;Q6ULP2-8;Q6ULP2-6;Q6ULP2;Q6ULP2-9;A0A0U1RR74 B8ZZI9 AFTPH Aftiphilin 1 KS(0.41)S(0.574)GT(0.015)GT(0.002)EPVAK;KS(0.391)S(0.605)GT(0.003)GTEPVAK 79.02199999999999 0.0072604 8479000.0 38980.0 37837.0 42795.0 58445.0 45804.0 47724.0 40676.0 44897.0 46242.0 49970.0 True False 51374.82916563215 50067.07030713736 42227.510338243716 44971.40821624873 39444.90523459134 44739.81073564796 44296.0852001468 37959.20028042331 48686.25771508596 48220.565509684275 1.0654132447972722 1.0382928897232082 0.8757157841660534 0.9326188471849629 0.8180100091665143 0.9278159694469518 0.9186139716932745 0.7871994009029167 1.0096575434252872 1.0 15.557360949885016 -5.209046656221294 5.508960014822214 0.8997378881309587 1.0559481599945735 0.4195897655059079 0.06676201942761804 0.17336260792147892 11.99805066513261 0.015957058107722855 0.04333442906898451 6.179500102524023e-06 5.209046656221294 0.1562102718636148 KSS(ph)GTGTEPVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 KSSGTGTEPVAK 12 1 B8ZZI9;Q6ULP2-7;Q6ULP2-8;Q6ULP2-6;Q6ULP2;Q6ULP2-9;A0A0U1RR74 B8ZZI9 AFTPH Aftiphilin 1 KS(0.293)S(0.707)GTGTEPVAK;KS(0.228)S(0.756)GT(0.009)GT(0.006)EPVAK;KS(0.082)S(0.905)GT(0.01)GT(0.003)EPVAK;KS(0.226)S(0.771)GT(0.002)GT(0.001)EPVAK 162.94 0.00035003 29936200.0 78712.0 82688.0 84553.0 98777.0 93918.0 86289.0 90821.0 100292.0 80605.0 68910.0 True False 92036.38696713587 90896.71817404579 86569.06418903831 93242.84492935457 75515.442096004 81763.85293689702 82217.77739290126 97659.44126815762 81783.69563532161 81402.83750874025 1.130628732164943 1.1166283750770503 1.063464945920876 1.1454495664152131 0.9276757961649172 1.0044349243737112 1.0100111975098351 1.1997056153929755 1.0046786836704613 1.0 16.312791463825242 -6.2102281265765376 24.999957002126376 1.0326831518141575 1.1106148747221007 0.29053448124476544 0.0677943841230537 564.5695635372996 275607.36223715346 0.020996493566353115 0.027106344234731947 6.162712013626007e-07 6.2102281265765376 0.07793172290794326 KSS(ph)GTGTEPVAK ddPTM_PC-9_Lapatinib_30min_R1 1 KSSGTGTEPVAK 12 1 B8ZZI9;Q6ULP2-7;Q6ULP2-8;Q6ULP2-6;Q6ULP2;Q6ULP2-9;A0A0U1RR74 B8ZZI9 AFTPH Aftiphilin 1 KS(0.391)S(0.586)GT(0.012)GT(0.012)EPVAK 64.65 0.01994 6164600.0 34930.0 30696.0 33684.0 23827.0 21173.0 24643.0 23550.0 25145.0 30612.0 25311.0 True False 34431.89179462253 30624.925297956623 30914.63154400015 25579.317064541927 19927.645767719623 23589.076335638743 24769.303768965015 26313.328496335547 27164.154201349214 29685.972625212493 1.1598707655406006 1.031629506790917 1.0413885350599612 0.8616634323383173 0.6712815517048258 0.7946202953648346 0.8343773701363681 0.8863893000422517 0.915050166767267 1.0 14.85749376159938 -5.728801642121027 3.549356279887764 0.8345942952092754 1.0829283366725848 0.5935270866525 0.08567963187719496 0.15686142915150658 4.108946545664389 0.025213465528752626 0.04410049844184756 1.867232328133755e-06 5.728801642121027 0.2483340414633094 KSS(ph)INEQFVDTR ddPTM_PC-9_AZD4547_30min_R2 1 KSSINEQFVDTR 12 1 Q9Y2L6;E9PGA7;Q9Y2L6-2 Q9Y2L6 FRMD4B FERM domain-containing protein 4B 1 KS(0.077)S(0.923)INEQFVDTR 94.67299999999999 0.0071031 6264100.0 12466.0 12304.0 15557.0 20873.0 20224.0 13393.0 13644.0 17518.0 15692.0 11606.0 True False 16429.92869109211 16281.027382166081 15350.704015236775 16061.0523346353 17416.246691650827 12555.533592794685 14858.289568069691 14810.995623593013 16521.44708414708 11199.677472591462 1.4670001641833383 1.4537050215963818 1.3706380431761505 1.4340638267433052 1.555066807439137 1.121062068396287 1.3266712014191309 1.3224484062009276 1.475171684593541 1.0 13.45116956581512 -6.751726989208375 24.9999616381693 1.2740737177652002 1.4499904571229927 0.39064310002416613 0.12726770996783632 247.95754032299578 638248.8553070078 0.04129296080795284 0.040794352309605056 1.7712220527627665e-07 6.751726989208375 0.1759167393577925 KSS(ph)ISSISGR ddPTM_PC-9_Lapatinib_30min_R1 1 KSSISSISGR 10 1 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 KS(0.055)S(0.867)IS(0.012)S(0.012)IS(0.055)GR 63.602 0.024957 38515000.0 29830.0 34847.0 29816.0 31245.0 35373.0 36681.0 33918.0 43051.0 33612.0 40342.0 True False 29404.61872984797 34766.313912493315 27364.64357308835 33542.861530264534 33292.42968599377 35112.23913758735 35674.1080779514 45051.30662540237 29826.262609948713 47315.06094766394 0.6214642471320699 0.7347832427173449 0.578349536595903 0.7089256752171769 0.7036328183708596 0.742094344471534 0.753969399245014 0.952155734835351 0.6303756565576465 1.0 15.53001186323974 -14.522878744267043 0.07933289213380723 1.9694925013785085 0.42586727175502276 0.5369202146481835 0.08800777941027212 187.46110378135876 1.050300048959363 31.563237325907057 2.9860843484739754 3.0000000069995903e-15 14.522878744267043 -1.5436252296234858 KSS(ph)LGNDETDKEK ddPTM_PC-9_Lapatinib_30min_R1 1 KSSLGNDETDKEK 13 2 O75128-3;O75128;O75128-7;A0A0J9YWK3;A0A3B3IU00;H7C1N2;J3KR05;O75128-5;O75128-4;O75128-2 O75128-3 COBL Protein cordon-bleu 1 KS(0.055)S(0.945)LGNDETDKEK 101.3 0.0057253 17086000.0 24388.0 23090.0 22054.0 22482.0 24504.0 18052.0 15767.0 18301.0 20008.0 17666.0 True False 24040.22264778854 23036.53652364537 20240.805250901874 24135.40127775345 23062.722896717583 17279.95804126732 16583.33811147649 19151.331271085193 17754.488346419545 20719.54456153466 1.160267909190371 1.1118263944088882 0.97689431303806 1.164861573384207 1.1130902432832899 0.833993140628542 0.8003717486272869 0.9243123667225379 0.8568956857951563 1.0 14.338704670892605 -6.7571515641447935 24.96294769260639 0.8732126706436497 1.101911344123723 0.7149835900774614 0.07001228334572947 56.98096124785533 331733.82688458276 0.023465416073572738 0.022681648959961196 1.7492361173305673e-07 6.7571515641447935 0.22869867348007322 KSS(ph)PEMEDAR ddPTM_PC-9_AZD4547_30min_R2 2 KSSPEMEDAR 10 1 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 KS(0.13)S(0.87)PEMEDAR;KS(0.332)S(0.668)PEMEDAR 87.641 0.010098000000000001 11213400.0 18818.1 18700.3 21230.0 32050.0 22674.9 20122.4 18703.4 23088.0 18789.0 22034.5 True False 24801.864359204246 24744.806270702236 20948.47632856442 24661.367667563896 19526.88153226433 18864.143146991086 20367.966366713168 19520.28010945972 19782.148181496268 21263.078861779813 1.1664286494175293 1.1637452144891771 0.985204281315022 1.1598211071818239 0.9183468517987637 0.8871783465422408 0.9579029687617064 0.9180363876911185 0.9303520111122993 1.0 14.376062891612191 -6.268366846812726 24.893102617883358 0.92992836243198 1.1124676624740393 0.7169292350527363 0.05636967686788624 277.727183521007 997980.4880745368 0.017333392007728234 0.02007739980793799 5.390550924683295e-07 6.268366846812726 0.18253930004205932 KSS(ph)PEMEDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSSPEMEDAR 10 1 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 KS(0.005)S(0.995)PEMEDAR 94.54700000000001 0.006022100000000001 4698500.0 15374.0 14645.0 12001.0 14443.0 14840.0 14299.0 15576.0 12878.0 14621.0 12516.0 True False 17976.514549658874 16098.858814566809 12287.14935404595 13633.805534837782 11932.208529831361 13549.135268049125 14100.528519525536 12539.966145368886 14834.804464785559 14785.051723398514 1.2158574001611113 1.0888605001691736 0.831052172418211 0.9221344497064698 0.8070454370442072 0.9164077016116587 0.953701669992154 0.8481516588490116 1.0033650704994361 1.0 13.85185167007972 -5.050316280017538 3.6817317122771014 0.9038596874116194 1.2003777636630453 0.7095532050778668 0.06409362070424098 0.10689082032474898 2.880292087040191 0.015857000007531034 0.058403700153112297 8.90602110538578e-06 5.050316280017538 0.2965180762514259 KSS(ph)PEMEDAR ddPTM_PC-9_Lapatinib_30min_R1 1 KSSPEMEDAR 10 1 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 KS(0.335)S(0.665)PEMEDAR 96.82 0.0057228 0.0 23798.0 20679.0 24139.0 18727.0 20468.0 17977.0 19910.0 18679.0 21332.0 19692.0 True False 23458.636155981294 20631.11904601398 22154.38459923463 20104.24605144066 19264.11248163627 17208.16561643379 20940.842379621816 19546.894531042046 18929.365524081455 23095.735962059356 1.015712865548779 0.8932869288039083 0.9592413350944461 0.8704743630801381 0.8340982297893644 0.7450797690405968 0.9066973407568608 0.846342137057369 0.8196043440736321 1.0 14.495338898972863 -5.848897391924428 4.048952078103964 0.847991952241226 0.9502634460419844 0.28717976368330655 0.06772655382036624 0.2599285238984031 8.000188158612387 0.018667768977887425 0.029231603894166288 1.416128320329613e-06 5.848897391924428 0.1022714938007584 KSS(ph)PQSTDTAMDLLK ddPTM_PC-9_Lapatinib_30min_R1 1 KSSPQSTDTAMDLLK 15 1 Q9UGU5 Q9UGU5 HMGXB4 HMG domain-containing protein 4 1 KS(0.408)S(0.582)PQS(0.009)T(0.001)DTAMDLLK 64.675 0.033893 0.0 29327.0 22517.0 20238.0 21506.0 20558.0 27005.0 18299.0 19212.0 26197.0 22773.0 True False 28908.791602086887 22464.863269940346 18574.10976093915 23087.6229819129 19348.818858583094 25850.05910172967 19246.432682305338 20104.659656854194 23246.417993360294 26709.282706884904 1.0823499799429286 0.8410882282566703 0.6954177678515967 0.8644044557573072 0.7244230056988955 0.9678305248933641 0.7205896501797162 0.7527218112701984 0.8703497674749617 1.0 14.705053611639453 -4.770470990738049 4.791480482771455 0.8121555499486194 1.0995620572639224 0.3693503720994791 0.09947628636344645 0.16883994948485515 9.443190185830382 0.023124059928631258 0.1628111254032384 1.6964029119035686e-05 4.770470990738049 0.28740650731530304 KSS(ph)PSTGSLDSGNESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSSPSTGSLDSGNESK 16 1 A0A0U1RQT1;A0A087X1H5;Q15057 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 KS(0.381)S(0.536)PS(0.063)T(0.008)GS(0.011)LDSGNESK 54.058 0.032722 14988000.0 39431.0 41798.0 32229.0 42369.0 46330.0 40315.0 40269.0 40716.0 37263.0 31125.0 True False 46105.889502250466 45947.429206641405 32997.46158916315 39995.20229215134 37251.96908268778 38200.8104294986 36454.42879768704 39647.248142168006 37807.90088032995 36767.71611463558 1.2539775208908823 1.2496677537268026 0.8974574729167999 1.0877804367139097 1.0131706023442517 1.0389769739951993 0.991479282641006 1.078316858696214 1.0282907092311975 1.0 15.166151943568966 -5.23954218037039 24.604184035837434 1.0220050458373693 1.2518227386213423 0.779999604290577 0.04984020434662277 272.5925111161 306289.58370670443 0.011897230900864746 0.031417304667045926 5.760468679289966e-06 5.23954218037039 0.22981769278397302 KSS(ph)PSTGSLDSGNESK ddPTM_PC-9_Lapatinib_30min_R1 4 KSSPSTGSLDSGNESK 16 1 A0A0U1RQT1;A0A087X1H5;Q15057 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 KS(0.384)S(0.472)PS(0.066)T(0.066)GS(0.01)LDS(0.001)GNESK;KS(0.22)S(0.742)PS(0.037)T(0.001)GSLDSGNESK;KS(0.168)S(0.672)PS(0.125)T(0.033)GS(0.002)LDSGNESK;KS(0.1)S(0.881)PS(0.012)T(0.003)GS(0.003)LDSGNESK 123.42 1.9065e-05 164448000.0 139316.0 138817.0 142839.0 144070.0 156048.0 150979.0 133007.0 127817.0 131586.0 107846.0 True False 137329.3282925747 138495.57776539092 131095.32879448525 154665.388403431 146869.5634421722 144521.98011923887 139893.4516517508 133755.8444388994 116765.39901799081 126487.03740423766 1.085718593073584 1.0949389013103008 1.0364329142718398 1.2227765910046469 1.161143200569987 1.1425833277868913 1.1059904202251793 1.0574668138635541 0.9231412278621276 1.0 16.9486300172153 -8.001904139054577 2.8431207704966384 0.9628321401406283 1.1235429163796355 0.6135979367784876 0.05016870001222936 0.18965709898398114 2.96897126784086 0.04019475849393438 0.014431648686322626 9.956251554327723e-09 8.001904139054577 0.1607107762390072 KSS(ph)SLESLQTAVAEVR ddPTM_PC-9_AZD4547_30min_R2 1 KSSSLESLQTAVAEVR 16 1 R4GN62;A0A087WZG6;A0A087X1S9;Q8TEW8-5;Q8TEW8-2;Q8TEW8 R4GN62 PARD3B Partitioning defective 3 homolog B 1 KS(0.129)S(0.439)S(0.43)LES(0.002)LQTAVAEVR 62.739 0.01661 2644800.0 9382.7 7901.4 10633.0 20825.0 16140.0 11124.0 11026.0 16589.0 10249.0 13187.0 True False 12366.203427716173 10455.373029701484 10491.999472521224 16024.11799304269 13899.239596679417 10428.414521484958 12007.292639807707 14025.551227296743 10790.741216251805 12725.327143810411 0.9717788224981772 0.8216191938756536 0.8244974257989527 1.2592303374170468 1.0922500804578525 0.81950070152478 0.943574377625965 1.1021760830815859 0.8479735801134521 1.0 13.635415125256014 KSS(ph)SYSSSSTTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSSSYSSSSTTVK 13 1 P55085 P55085 F2RL1 Proteinase-activated receptor 2;Proteinase-activated receptor 2, alternate cleaved 1;Proteinase-activated receptor 2, alternate cleaved 2 1 KS(0.142)S(0.787)S(0.063)YS(0.002)S(0.003)S(0.003)STTVK 75.46300000000001 0.0084043 7707200.0 46682.0 41788.0 56660.0 34225.0 69241.0 39084.0 25180.0 35352.0 32568.0 25969.0 True False 54584.34058847241 45936.43647272908 58010.98928424662 32307.484208947088 55673.72310067748 37034.36623655028 22794.76811258685 34424.04745854021 33044.24538739732 30676.97412950912 1.7793260951368104 1.497423972742521 1.8910270954149966 1.0531509422198695 1.8148375020834675 1.2072366094583558 0.743057904484128 1.1221461188842177 1.077167690916786 1.0 14.9048685669653 -6.9542201040640395 5.8677569797976465 0.9920970235028499 1.583180543682589 0.6068750138382023 0.23715687133747704 0.13037306230711285 10.66065080764897 0.0816451122892682 0.07118768995213498 1.1111684351265964e-07 6.9542201040640395 0.5910835201797391 KSS(ph)T(ph)VGEIVNLMS(ph)VDAQR ddPTM_PC-9_Lapatinib_30min_R1 1 KSSTVGEIVNLMSVDAQR 18 1 A0A0A0MS99;I3L4X2;P33527-8;P33527-6;P33527-7;P33527-5;P33527-4;P33527-2;P33527-3;P33527;P33527-9 A0A0A0MS99 ABCC1 Multidrug resistance-associated protein 1 3 KS(0.449)S(0.776)T(0.776)VGEIVNLMS(1)VDAQR 43.751999999999995 0.043188 0.0 7598.6 5934.5 5735.9 6396.4 8201.0 5837.3 6046.2 5393.5 8692.1 4258.4 True False 7490.242570587418 5920.759029864595 5264.316443214295 6866.81259376489 7718.63330378636 5587.652286410914 6359.24265171619 5644.101699939784 7713.104166129216 4994.4587660386715 1.4997105635388526 1.185465594415271 1.0540314155781207 1.3748862320093327 1.5454393890027753 1.1187703309126988 1.273259616228645 1.1300727394765087 1.5443323345818356 1.0 12.286112630776117 -10.750720079353702 5.6419651253993885 0.9999872386022859 1.2899949989663422 0.21113394697146448 0.17404159110041548 2.7669749068065793e-05 3.7867223578877238e-06 0.1669019749985177 0.04047789472475581 1.775333387550726e-11 10.750720079353702 0.2900077603640563 KSS(ph)TPEEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KSSTPEEVK 9 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 1 KS(0.084)S(0.888)T(0.028)PEEVK;KS(0.005)S(0.664)T(0.33)PEEVK;KS(0.003)S(0.616)T(0.381)PEEVK 158.42 0.00016892 34768500.0 51232.0 64762.0 57322.0 60582.0 88384.0 70175.0 59677.0 65617.0 66231.0 62839.0 True False 59904.5657218761 71191.1433628525 58688.77387489557 57187.786949493995 71065.78966985288 66494.8994639729 54023.962535935105 63894.623276958286 67199.50307825817 74231.21326674965 0.8069996849790022 0.9590459353941493 0.7906212399357886 0.7704008116368763 0.957357242895629 0.8957808519850494 0.7277795978061163 0.860751434135303 0.9052728646206678 1.0 16.179738328609787 -8.579670827398541 2.526919854067784 0.9993227790769301 0.8471488813022763 0.30273290283290466 0.07222072549704239 0.43124829213952953 6.565822905366052 0.07053310761064154 0.019090832536392877 2.6322623537781537e-09 8.579670827398541 -0.15217389777465384 KSS(ph)TPEEVK ddPTM_PC-9_Lapatinib_30min_R1 1 KSSTPEEVK 9 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 1 KS(0.096)S(0.827)T(0.077)PEEVK 89.35600000000001 0.013821 8235300.0 38023.0 32209.0 38684.0 34018.0 40528.0 32747.0 34613.0 35673.0 36096.0 41944.0 True False 37480.785047435784 32134.422039415054 35503.550844558275 36519.79720072134 38144.22272111371 31346.487146985422 36405.091777290305 37330.49781068915 32030.488372269076 49193.96451313313 0.7618980380698872 0.6532187913181148 0.7217054204907601 0.7423633683959704 0.7753841980133658 0.6372018896467873 0.7400316713155203 0.7588430446731563 0.6511060592345229 1.0 15.586193705254349 -10.691629988632332 4.053545374267425 1.0001154680170172 0.7162942890165421 0.7586131440535159 0.04810165057963682 6240374.515228802 5486543.747351359 5784.615998381378 0.01121994532450078 2.03408928169485e-11 10.691629988632332 -0.2838211790004751 KSS(ph)TPLSEAK ddPTM_PC-9_AZD4547_30min_R2 1 KSSTPLSEAK 10 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 KS(0.074)S(0.463)T(0.463)PLSEAK 104.7 0.0037715000000000005 7933300.0 24961.0 21415.0 24222.0 27896.0 25301.0 22632.0 22303.0 25042.0 21756.0 23301.0 True False 32898.07877894674 28336.979956850326 23900.800453626343 21465.008188903666 21788.392877049926 21216.817462266044 24287.923793363992 21172.334307912774 22905.977744245716 22485.239082272423 1.463096685722319 1.2602481055756918 1.0629551398664008 0.9546266379629863 0.9690087260058579 0.9435886976622626 1.0801719165402526 0.9416103707167269 1.0187117717731988 1.0 14.456690603604189 -5.029167554216846 1.6614878984871533 0.9849372133735184 1.5189532464743887 0.9353718553041079 0.04054586925869743 0.13411710668305984 0.5160550883948941 0.011511299076274345 0.09919118056331609 9.350448569105707e-06 5.029167554216846 0.5340160331008703 KSS(ph)TSGSDFDTK ddPTM_PC-9_AZD4547_30min_R2 1 KSSTSGSDFDTK 12 1 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 KS(0.061)S(0.892)T(0.035)S(0.009)GS(0.003)DFDTK 86.756 0.013146000000000001 6752700.0 9512.0 10392.0 11762.0 14057.0 13476.0 12575.0 12183.0 16282.0 13219.0 13758.0 True False 12536.618138109112 13751.010773363932 11606.028194845725 10816.375828485048 11605.090012692182 11788.683262106559 13267.26339840171 13765.991023138558 13917.729352876626 13276.336607609283 0.9442829380300434 1.0357533994341928 0.8741890581618557 0.8147108760624284 0.8741183924216541 0.8879470000293544 0.9993165878904899 1.0368817415527587 1.0483109734427591 1.0 13.696569492563714 -7.382229068607827 3.8845528587230937 1.0299424323745636 0.9042617991846411 0.5181477303000481 0.055169850553432 0.2226129521957006 5.872687018999935 0.02817881864305136 0.018231153510014485 4.147352328511657e-08 7.382229068607827 -0.1256806331899225 KSS(ph)TSGSDFDTK ddPTM_PC-9_Lapatinib_30min_R1 1 KSSTSGSDFDTK 12 1 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 KS(0.012)S(0.983)T(0.005)SGSDFDTK 177.63 0.0013319 8773200.0 19724.0 20485.0 23897.0 20890.0 32926.0 32759.0 34894.0 40801.0 34150.0 32121.0 True False 19442.732143061396 20437.568241094654 21932.280905087606 22426.320286997154 30989.357415006663 31357.9739349588 36700.64058234672 42696.763411373504 30303.667384557535 37673.07205145787 0.516090965889494 0.5424980530703432 0.582173943105308 0.5952878028201393 0.8225864185611972 0.8323710339344442 0.9741876248429409 1.1333496602839752 0.804385353633109 1.0 15.201246062229329 -6.4756783805800415 1.1132675178383846 0.9885502988451484 0.528107274815567 0.842837169330622 0.08080172320000084 0.17421837265153253 0.4563091397145151 0.03672317339096944 0.04411139076164236 3.344426218583853e-07 6.4756783805800415 -0.4604430240295815 KSSADTEFS(ph)DECTTAER ddPTM_PC-9_AZD4547_30min_R2 1 KSSADTEFSDECTTAER 17 1 Q9H6S0 Q9H6S0 YTHDC2 Probable ATP-dependent RNA helicase YTHDC2 1 KS(0.016)S(0.27)ADT(0.018)EFS(0.696)DECTTAER 177.04 6.3881e-06 5185600.0 15760.0 13761.0 19376.0 18591.0 21713.0 16040.0 17021.0 17954.0 16423.0 18098.0 True False 20771.352171635783 18208.97413897817 19119.06157994651 14305.132178086767 18698.524743661725 15037.016264349048 18535.83602595384 15179.621841876286 17291.086251780984 17464.394528602475 1.189354268057636 1.042634149678436 1.094745171304627 0.8191026694145281 1.0706655024906842 0.861009881546253 1.0613500511338425 0.8691753852110772 0.99007647951736 1.0 14.09212900649498 -4.867925209964441 1.1491947711236479 0.955809372016322 1.2620274182489981 0.3856058737692616 0.08751666117211476 1.3614897405431436 1.6729269601916408 0.02524877301531299 0.4869455446528373 1.3554228101864412e-05 4.867925209964441 0.3062180462326761 KSSEAS(ph)PTAQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSSEASPTAQR 11 1 J3KNN7;Q7Z569 J3KNN7 BRAP BRCA1-associated protein 1 KSSEAS(0.998)PT(0.002)AQR 94.023 0.0099965 1859600.0 2701.1 2554.4 2115.4 3322.1 5026.4 4572.2 2638.5 2809.6 3036.0 2190.6 True False 3158.342880843213 2807.9839505585146 2165.8391586991743 3135.9735073935162 4041.5130023143065 4332.425783101913 2388.562178914234 2735.850977017271 3080.3957564522916 2587.73843921994 1.2205031362425016 1.0851111951658323 0.8369621619687556 1.2118587643420555 1.5617934722693994 1.6742131729541798 0.9230307602627156 1.0572362861533944 1.1903814194532196 1.0 11.337476086107475 KSSEAS(ph)PTAQR ddPTM_PC-9_Lapatinib_30min_R1 1 KSSEASPTAQR 11 1 J3KNN7;Q7Z569 J3KNN7 BRAP BRCA1-associated protein 1 KS(0.007)S(0.002)EAS(0.495)PT(0.495)AQR 94.54700000000001 0.009678 1277500.0 2982.7 1163.9 2095.8 2100.7 2160.8 1169.0 1817.9 900.41 2927.5 701.78 True False 2940.1661510398085 1161.2050610598035 1923.4914140219532 2255.192485729771 2033.7059922962521 1119.004595072097 1912.0219669469868 942.2463357083121 2597.7741220583366 823.0817379369287 3.572143586139325 1.410801634319318 2.336938514567489 2.7399374591671264 2.470843293636642 1.3595303400569971 2.3230037538428556 1.1447785709230678 3.1561557040127157 1.0 9.6848918975307 -6.727137282153783 24.585102851615996 1.8386366189965433 2.4488712084147926 0.17478215551724585 0.7630086607901793 311.17247043979364 223023.40578875956 0.23708387374833834 0.2370711955622628 1.8744019087682663e-07 6.727137282153783 0.6102345894182493 KSSEASPT(ph)AQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSSEASPTAQR 11 1 J3KNN7;Q7Z569 J3KNN7 BRAP BRCA1-associated protein 1 KSSEAS(0.236)PT(0.764)AQR 111.66 0.006083600000000001 5030700.0 2795.0 1099.8 3322.5 3716.8 3147.1 5148.5 2103.9 4189.1 3735.2 2884.0 True False 3268.138296233676 1208.9808756750124 3401.721000651419 3508.559746028185 2530.4483466463803 4878.503596583745 1904.6033610830625 4079.140563718337 3789.8202336958498 3406.846370268561 0.9592854919301952 0.3548680346216224 0.998495567730359 1.0298555804122176 0.7427538760566141 1.431970528274562 0.5590517311565544 1.197336222530275 1.1124130124473735 1.0 11.73422117607962 -5.373462015557081 11.174033771069466 1.0068343952599355 0.6573268687403946 0.22522290838277992 0.26108975929811795 0.64830616420115 60.41327735983663 0.06384308530351286 0.1329695021092935 4.231925215367084e-06 5.373462015557081 -0.34950752651954087 KSSEGGVGVGPGGGDEPPT(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 KSSEGGVGVGPGGGDEPPTSPR 22 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 KSSEGGVGVGPGGGDEPPT(0.5)S(0.5)PR 82.36 0.00030095 15572000.0 20508.0 21113.0 29753.0 39941.0 38019.0 33260.0 25250.0 29217.0 27055.0 27928.0 True False 27029.117407100683 27937.364362782206 29358.45577973514 30733.21953229858 32740.7181057097 31180.246942160153 27497.201084268527 24702.18398986854 28485.072066122797 26950.249220621605 1.002926436257915 1.0366273103480352 1.089357487546751 1.1403686578446313 1.2148577119894455 1.1569557923902933 1.020294872198377 0.9165846218211257 1.0569502282868237 1.0 14.718010993814518 -7.434469648571239 5.622229219808191 0.9860273983917776 1.1087119854413388 0.40857539089663963 0.06440591692016984 0.23830443804374865 11.817580032857032 0.03075148856308461 0.020308758799187643 3.677310920101515e-08 7.434469648571239 0.1226845870495612 KSSEGGVGVGPGGGDEPPT(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSSEGGVGVGPGGGDEPPTSPR 22 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 KSSEGGVGVGPGGGDEPPT(0.611)S(0.389)PR 115.83 1.2938999999999998e-06 10685000.0 35842.0 32869.0 40644.0 38066.0 39547.0 42765.0 47051.0 45836.0 40948.0 36796.0 True False 41909.34268823163 36132.01709634662 41613.10710322836 35933.28543163711 31798.04924051489 40522.32811652012 42593.98866025909 44632.853567256425 41546.78703399485 43466.82352302429 0.9641685150062168 0.8312550623168394 0.9573533037486849 0.8266830313147524 0.7315475726831413 0.932258785716318 0.979919515804902 1.026825747770929 0.9558275407906813 1.0 15.407627049469024 -6.995519622052127 24.998007412186062 0.9876230481673198 0.8606060046802713 0.4696521553998352 0.06443127930155866 117.56913814221753 655964.4791685471 0.023471877763389104 0.020621191195623105 1.0103698495274274e-07 6.995519622052127 -0.12701704348704856 KSSEGGVGVGPGGGDEPPT(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 2 KSSEGGVGVGPGGGDEPPTSPR 22 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 KSSEGGVGVGPGGGDEPPT(0.5)S(0.5)PR;KSSEGGVGVGPGGGDEPPT(0.5)S(0.5)PR 133.02 1.3712e-05 32107000.0 128500.0 117894.0 124784.0 107911.0 145114.0 144557.0 126341.0 126839.0 155278.0 106872.0 True False 126667.56643598613 117621.02368638551 114524.7412001694 115847.13492054313 136578.67982510102 138374.63408882567 132882.31878873915 132732.40298853477 137788.9564901707 125344.68280201135 1.0105539669047179 0.9383806401439001 0.9136784954896522 0.9242285538631894 1.0896248390594627 1.1039529639035095 1.0601352671547617 1.0589392387564833 1.0992804274579062 1.0 16.935541271902053 -6.262204369906045 24.99899440923859 1.0729412868419244 0.9437560040176982 0.7263508465299917 0.03659390810468301 34.285725211225554 1120414.035450701 0.011064065852141198 0.013292050274017147 5.467586091723413e-07 6.262204369906045 -0.12918528282422614 KSSEGGVGVGPGGGDEPPTS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 KSSEGGVGVGPGGGDEPPTSPR 22 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 KSSEGGVGVGPGGGDEPPT(0.159)S(0.841)PR 111.72 4.9809e-06 16062000.0 85922.0 73611.0 110600.0 138130.0 129570.0 122970.0 90958.0 122840.0 97061.0 109600.0 True False 113243.40871137619 97404.31620843855 109133.37173524387 106286.26258722635 111581.44204100063 115280.66646053609 99053.08579100581 103857.90058238182 102191.44630604124 105762.93735964362 1.0707286648657977 0.9209683338995982 1.0318678211833243 1.0049480965700033 1.0550145904285104 1.0899911570016982 0.9365576284457648 0.9819876714393456 0.9662311662027915 1.0 16.690474624997016 -7.285417066024803 24.986597090060485 0.969693093108436 1.024243413423518 0.27507769355197065 0.04550418286355936 1192.9821971700471 1243173.1084980266 0.01938296161298047 0.01307790055177703 5.183020588324941e-08 7.285417066024803 0.05455032031508211 KSSEGGVGVGPGGGDEPPTS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSSEGGVGVGPGGGDEPPTSPR 22 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 KSSEGGVGVGPGGGDEPPT(0.24)S(0.76)PR 157.17 2.5180000000000003e-06 12085000.0 24654.0 25677.0 31436.0 33916.0 34295.0 36731.0 37895.0 38941.0 39550.0 31306.0 True False 28827.435261304123 28226.042866618754 32185.553461693893 32015.796477155578 27575.14093871742 34804.76169877001 34305.31126395867 37918.8400114 40128.34392875104 36981.52998184034 0.7795089947727891 0.7632470284620204 0.8703142751935495 0.8657239571450082 0.7456462983618608 0.9411390419990946 0.9276336398414069 1.0253453556415846 1.0850915023920302 1.0 15.174517292002577 -7.293019521400271 1.246330012122777 1.0463325711991558 0.808442411956256 0.7854204273171699 0.05106556575350807 0.2121308001788128 0.6389262084197679 0.03413616035672603 0.01907968479595936 5.0930797730938664e-08 7.293019521400271 -0.2378901592428998 KSSGEIVYCGQVFEKS(ph)PLR ddPTM_PC-9_Lapatinib_30min_R1 1 KSSGEIVYCGQVFEKSPLR 19 2 M0R117;Q02543;M0R3D6;M0R1A7;M0R0P7 M0R117 RPL18A 60S ribosomal protein L18a 1 KSSGEIVY(0.002)CGQVFEKS(0.998)PLR 42.059 0.038585 7139200.0 17566.0 24904.0 24789.0 20170.0 25328.0 21683.0 18831.0 20518.0 25283.0 28045.0 True False 17315.505618790132 24846.336318097186 22750.944108307183 21653.369085147555 23838.2568367639 20755.66863554174 19805.977039209352 21471.3411846416 22435.36229820696 32892.54088238646 0.5264265135583479 0.7553790510419973 0.6916748751535344 0.6583063668621191 0.7247313888581037 0.6310144512629043 0.6021418992843816 0.6527723492513534 0.6820805476362822 1.0 15.00547283730714 -8.856567573546586 3.4431386571623124 0.9999986514796726 0.6599299035911853 0.7437004669230318 0.06031323676203646 3.1708987442979626 32.28719551151718 0.05687577039077012 0.014991252690586728 1.3913372944882016e-09 8.856567573546586 -0.3400687478884873 KSSPST(ph)GSLDSGNESK ddPTM_PC-9_Lapatinib_30min_R1 1 KSSPSTGSLDSGNESK 16 1 A0A0U1RQT1;A0A087X1H5;Q15057 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 KS(0.051)S(0.185)PS(0.261)T(0.491)GS(0.01)LDS(0.002)GNESK 86.911 0.0149 7915800.0 13249.0 19317.0 19417.0 18921.0 16688.0 17088.0 13344.0 15205.0 18547.0 16085.0 True False 13060.066830430975 19272.27267333295 17820.609211787505 20312.5134586057 15706.44464987035 16357.186074073576 14034.887027306542 15911.479808581515 16458.041551431594 18865.270818084733 0.6922809089976731 1.0215741326574572 0.9446251465790892 1.0767146496054327 0.832558663022942 0.8670528099916359 0.7439536470291399 0.8434270550374693 0.8723989022015254 1.0 14.203445190278094 KSSS(ph)GPVWSGASSACTSPAVGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KSSSGPVWSGASSACTSPAVGK 22 1 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 KS(0.308)S(0.308)S(0.382)GPVWS(0.002)GASSACTSPAVGK;KS(0.231)S(0.231)S(0.532)GPVWS(0.004)GAS(0.001)SACTSPAVGK 62.848 0.0021482 14173400.0 117561.0 105569.0 100793.0 140355.0 159730.0 135983.0 134241.0 169637.0 123594.0 114460.0 True False 137461.75536441014 116049.19263878462 103196.28737958132 132491.36438704975 128432.05313139886 128851.81209560984 121524.72065932406 165184.20849525902 125401.3284331238 135210.69193513837 1.016648560827953 0.8582841414231822 0.7632257915600742 0.9798882210484279 0.9498661037324528 0.9529705842894515 0.8987804064904898 1.2216800767094602 0.927451273552241 1.0 17.044849713275127 -7.656102577536519 20.19173107112938 1.056984742629458 0.9139527040491148 0.2875630283967625 0.09534860006208028 3.1944193783702977 597.6686697382466 0.04399311399151423 0.025399261500228157 2.207483278223261e-08 7.656102577536519 -0.1430320385803433 KSSSGPVWSGASSACTS(ph)PAVGK ddPTM_PC-9_AZD4547_30min_R2 2 KSSSGPVWSGASSACTSPAVGK 22 1 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 KSSSGPVWSGASSACT(0.01)S(0.99)PAVGK;KSSSGPVWSGAS(0.001)S(0.017)ACT(0.11)S(0.872)PAVGK 180.83 1.0643e-13 18696900.0 62949.0 60290.0 66203.0 89457.0 83677.0 71482.0 52449.0 74582.0 56515.0 71250.0 True False 82965.47257946071 79777.5634647915 65325.10496372823 68834.07074687244 72059.89292015761 67012.21923991252 57116.85939282373 63057.06562386201 59502.267522340786 68755.55918681218 1.2066729375880647 1.1603070996489462 0.9501065184596456 1.0011418939935743 1.0480591500153085 0.9746443783234614 0.830723509027604 0.9171195226924547 0.8654175491565743 1.0 16.069188745975957 -3.0409944114551113 0.43337196975912073 0.907345968682541 2.5948934645012023 0.6905286430183282 0.06276146803083761 12.515103704169915 0.5487488271305632 0.04398443259425893 14.978626930740699 0.0009099249815627094 3.0409944114551113 1.6875474958186611 KSSSGPVWSGASSACTS(ph)PAVGK ddPTM_PC-9_Lapatinib_30min_R1 1 KSSSGPVWSGASSACTSPAVGK 22 1 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 KSSSGPVWSGASS(0.001)ACT(0.071)S(0.928)PAVGK 123.71 2.9219e-07 6221600.0 33110.0 24266.0 35723.0 28329.0 26972.0 26208.0 24432.0 15574.0 25123.0 18806.0 True False 32637.845328369636 24209.813567898607 32785.99283476775 30412.409162773678 25385.559988992256 25087.14493383193 25696.969413305877 16297.624895682251 22293.38318308167 22056.592042580127 1.479732012332751 1.0976225847203276 1.4864487120890921 1.378835366046699 1.1509284816070213 1.1373989637837676 1.165047137096158 0.7389004096471375 1.0107356177257312 1.0 14.428922277319897 -7.023732693174659 1.0571565146321356 0.9203199783654102 1.346195042615554 0.5952538700507872 0.14027985109830843 0.3536084454615074 0.8103127040331867 0.08709929291452065 0.061124843830776286 9.468197464979348e-08 7.023732693174659 0.42587506425014376 KSSSQPS(ph)PSDPK ddPTM_PC-9_Lapatinib_30min_R1 2 KSSSQPSPSDPK 12 1 A0A0A0MT50;A0A087X1S4;A0A087WUP2;E7ESE9;J3KNW2;E7EUP4;B5MDK9;Q9H322;Q9NNX9;Q9H320;Q9H321-2;Q9H321 A0A0A0MT50 VCX3B;VCX;VCX3A;VCX2 Variable charge X-linked protein 2;Variable charge X-linked protein 3;Variable charge X-linked protein 1;Variable charge X-linked protein 3B 1 KS(0.008)S(0.008)S(0.009)QPS(0.708)PS(0.268)DPK;KS(0.005)S(0.005)S(0.005)QPS(0.866)PS(0.118)DPK 54.7 0.038403 6717800.0 78500.0 70693.0 65999.0 71700.0 74082.0 68328.0 60104.0 65972.0 62703.0 62814.0 True False 77380.57560486313 70529.31470186508 60572.816983507466 76973.05718418826 69724.6424108158 65405.770720347566 63215.89102886939 69037.29996262692 55640.72784813794 73671.31620560613 1.0503487597385255 0.9573510877018653 0.8222035400379896 1.0448171846063867 0.946428623810986 0.8878051063701563 0.8580801088505445 0.9370987721999383 0.7552563292455996 1.0 16.168815397473892 -6.735168468337505 4.517070704377879 0.8812482071096065 0.9614968529270848 0.17714905292806382 0.08243170172254123 0.36126090822906615 17.18570316675683 0.02791633801145595 0.026720208842046202 1.8400580811421755e-07 6.735168468337505 0.08024864581747826 KSSSQPSPS(ph)DPK ddPTM_PC-9_AZD4547_30min_R2 1 KSSSQPSPSDPK 12 1 A0A0A0MT50;A0A087X1S4;A0A087WUP2;E7ESE9;J3KNW2;E7EUP4;B5MDK9;Q9H322;Q9NNX9;Q9H320;Q9H321-2;Q9H321 A0A0A0MT50 VCX3B;VCX;VCX3A;VCX2 Variable charge X-linked protein 2;Variable charge X-linked protein 3;Variable charge X-linked protein 1;Variable charge X-linked protein 3B 1 KS(0.038)S(0.038)S(0.008)QPS(0.038)PS(0.877)DPK 64.244 0.020382 2818000.0 27315.0 24721.0 29058.0 28720.0 30194.0 31523.0 26553.0 25112.0 28265.0 29678.0 True False 36000.601812705034 32711.579804496712 28672.67193384009 22099.04771957676 26002.084286377823 29551.8618267503 28916.165560023026 21231.517416352766 29759.030195858828 28638.982253280155 1.2570489235378368 1.142204688532537 1.0011763574648704 0.7716422156393373 0.9079262683435506 1.0318754195032747 1.0096785320194512 0.7413502766468254 1.0391092090030674 1.0 14.80569260384733 -5.20087838043758 2.4776391862984553 0.9234581439541851 1.2398169383324267 0.5449098373339838 0.09903157501025486 0.22944667213011205 2.6290936448350966 0.02711133769588561 0.10187340848384119 6.2968249407144535e-06 5.20087838043758 0.31635879437824155 KSSSYSS(ph)SSTTVK ddPTM_PC-9_Lapatinib_30min_R1 1 KSSSYSSSSTTVK 13 1 P55085 P55085 F2RL1 Proteinase-activated receptor 2;Proteinase-activated receptor 2, alternate cleaved 1;Proteinase-activated receptor 2, alternate cleaved 2 1 KS(0.001)S(0.226)S(0.011)YS(0.005)S(0.334)S(0.334)S(0.071)T(0.015)T(0.002)VK 109.44 0.00066718 0.0 20128.0 17085.0 13968.0 8779.5 12342.0 8901.2 7185.5 8758.1 14843.0 5632.6 True False 19840.971028976855 17045.440732199277 12819.60495803925 9425.173717553444 11616.067825305596 8520.516425710657 7557.530031078479 9165.033299015962 13171.22503628075 6606.187405032271 3.0033920947902524 2.580223612671795 1.9405451544220347 1.42671909524907 1.7583618376398227 1.2897781887356303 1.1440078168720313 1.3873407969072278 1.9937710253644263 1.0 12.68960218139357 -5.190465355752877 1.213368066467826 1.4114081976780002 3.2417928838456103 0.8079654558746463 0.267763753415829 0.3391726481958563 0.6823508498123262 0.08538664666020784 0.6527473348038388 6.449627673518685e-06 5.190465355752877 1.83038468616761 KSST(ph)PEEVK ddPTM_PC-9_AZD4547_30min_R2 2 KSSTPEEVK 9 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 1 KS(0.015)S(0.241)T(0.745)PEEVK;KSS(0.374)T(0.626)PEEVK 147.33 8.0446e-11 129280000.0 222282.0 189167.0 157436.0 155197.0 163491.0 188457.0 184839.0 131216.0 233827.0 267962.0 True False 292963.0522471797 250311.5333876959 155348.29577314487 119418.72941974769 140793.09671008124 176672.7539981565 201289.31291941047 110939.58224371396 246186.61785271822 258580.7319412847 1.132965515441816 0.9680208247091416 0.6007728983009432 0.46182377365558624 0.5444840984596284 0.6832402115648476 0.7784389478993228 0.42903267157935315 0.9520686866514835 1.0 17.980255251640635 -5.107831068004085 3.5454765431973945 0.6521397053972277 1.1070824654222067 0.4017610280831261 0.18190363403824492 0.20680444654263413 4.63436539977423 0.04532162143333783 0.15456151534474719 7.801335080741173e-06 5.107831068004085 0.454942760024979 KSST(ph)PEEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KSSTPEEVK 9 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 1 KS(0.001)S(0.317)T(0.682)PEEVK;KS(0.008)S(0.348)T(0.643)PEEVK 136.38 0.0034272 33303100.0 59479.0 85183.0 63981.0 75398.0 103442.0 82693.0 63172.0 73127.0 87942.0 86746.0 True False 69547.61993620142 93639.40528516535 65506.549689293715 71173.6945036142 83173.28266461004 78356.43350729335 57187.89083432633 71207.49373446105 89227.9853800815 102472.36311904162 0.6786963608461757 0.9138015600985501 0.6392606522911459 0.6945647815395072 0.8116655079768978 0.7646591834353139 0.5580811166410933 0.6948946190666031 0.8707517096724491 1.0 16.64487534058391 -8.49205230019967 3.398029512369014 0.998468685558062 0.7222970253308262 0.49482488745153885 0.09174608743750794 0.18115039845193773 4.8949456275904595 0.09040728169608293 0.023931467532225147 3.2206809153035245e-09 8.49205230019967 -0.2761716602272358 KSST(ph)PEEVK ddPTM_PC-9_Lapatinib_30min_R1 2 KSSTPEEVK 9 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 1 KS(0.001)S(0.054)T(0.945)PEEVK;KS(0.005)S(0.066)T(0.93)PEEVK 103.21 0.0099834 56740000.0 108029.0 160324.0 122430.0 126151.0 158966.0 111247.0 173410.0 172901.0 150284.0 135179.0 True False 106488.48664990763 159952.77962827697 112364.27799346663 135428.56536739966 149615.93241918067 106489.22513942323 182388.3212983533 180934.61166613267 133357.43335932193 158544.5100353049 0.6716630340980878 1.0088824872753934 0.7087238654207907 0.8541990216958143 0.9436840946801879 0.6716676920298916 1.1503919073434887 1.1412228126085344 0.8411356112528003 1.0 17.2745283961424 -7.268603420585869 24.999317693712666 1.0449561493829376 0.8223613651653563 0.40630591904547175 0.13145451370608507 568.0716585391707 1982308.7179421717 0.052059308511736575 0.035911240119298415 5.387615322804929e-08 7.268603420585869 -0.22259478421758128 KSST(ph)PLSEAK ddPTM_PC-9_Lapatinib_30min_R1 1 KSSTPLSEAK 10 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 KSS(0.221)T(0.761)PLS(0.019)EAK 198.37 0.0022855 7420000.0 37495.0 35557.0 44722.0 35175.0 33067.0 32282.0 29661.0 27444.0 30712.0 22927.0 True False 36960.31442425911 35474.66995111558 41045.1297919123 37761.88684036019 31122.064072223326 30901.37411301749 31196.701447612377 28719.148429247707 27252.89114830252 26889.901401692798 1.3745053904114481 1.3192562301058623 1.526414291326795 1.4043148123251568 1.1573885529481376 1.1491813841709422 1.1601642185883378 1.0680272865351508 1.0134991103606974 1.0 14.714776844780703 -6.358893600738479 2.815461004334212 1.0897312499650915 1.4115043547885129 0.8392423772841197 0.06806229497627457 0.11539543367239177 1.7771449231505805 0.024125549463526935 0.028363235819197197 4.3762930829751054e-07 6.358893600738479 0.32177310482342136 KSST(ph)SGSDFDTK ddPTM_PC-9_Lapatinib_30min_R1 1 KSSTSGSDFDTK 12 1 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 KS(0.027)S(0.295)T(0.676)S(0.001)GSDFDTK 171.21 0.0037323 6744300.0 24953.0 24351.0 27573.0 28264.0 32915.0 41872.0 41719.0 41194.0 35593.0 35102.0 True False 24597.165644180226 24294.616755620988 25306.05437485798 30342.628845940028 30979.004413379804 40081.23216839939 43879.00568736524 43108.02362609055 31584.141529093897 41169.33392952506 0.5974632887256912 0.5901143991595604 0.6146821422512607 0.737020154318782 0.7524776686067017 0.9735700907139202 1.0658177215710771 1.0470906257527557 0.7671764032704684 1.0 15.329282487320985 -6.426521380099279 1.4549403453713858 0.9831163222563052 0.6047154915012883 0.7850347836266818 0.08376985098429854 0.18196913163623335 0.7812136511697778 0.03410690810220654 0.0409701705336559 3.745231089976538e-07 6.426521380099279 -0.37840083075501685 KSSTPEEVK ddPTM_PC-9_AZD4547_30min_R2 2 KSSTPEEVK 9 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 0 ; 63.693999999999996 0.0357 8177200.0 40184.0 33125.0 40517.0 46491.0 43351.0 40753.0 42290.0 36864.0 46392.0 52222.0 False True 52961.67612087638 43832.00845531954 39979.718106662476 35773.218228789796 37332.46194272922 38204.70846764442 46053.72807341445 31167.51585044712 48844.18640885487 50393.723675139714 1.0509577832011547 0.8697910227448185 0.7933471708578129 0.7098744768177844 0.7408157052134274 0.758124339331003 0.9138782513929156 0.6184801117569073 0.9692513838375221 1.0 15.620956442905644 -4.78961332680617 2.4117557463130805 0.7952033256736295 1.1075616227378942 0.27294527449603034 0.11370217231621386 0.625971269249125 4.572795738055088 0.027629926525318704 0.41194777014989303 1.623254715636184e-05 4.78961332680617 0.31235829706426466 KSSTPEEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KSSTPEEVK 9 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 0 ; 92.611 0.004362899999999999 9308100.0 59770.0 75493.0 63053.0 66208.0 104155.0 77956.0 58596.0 75396.0 77900.0 74637.0 False True 69887.8804886894 82987.44612414417 64556.42264983413 62498.58040923209 83746.57543292367 73867.85012630525 53045.36268169738 73416.93488866535 79039.14012767914 88168.0972738333 0.7926663118478215 0.9412412050404241 0.7321970717972306 0.7088570848378799 0.949851227625144 0.8378070119499776 0.6016389637733545 0.8326927444135076 0.8964596330370911 1.0 16.42796910527749 -8.482738692200602 2.549686957991888 0.9970581756438862 0.7986528272333894 0.29632180169960964 0.09850863446126343 0.3480287028357069 5.0894490196085655 0.0974603946512021 0.02649347672223098 3.2904955499553616e-09 8.482738692200602 -0.19840534841049684 KSSTPEEVK ddPTM_PC-9_Lapatinib_30min_R1 3 KSSTPEEVK 9 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 0 ;; 80.24 0.012008 22620300.0 157388.0 143738.0 130782.0 124221.0 146793.0 119157.0 151341.0 224329.0 182911.0 150081.0 False True 155143.6182585759 143405.18349223657 120029.60879311901 133356.6267291085 138158.92434614204 114060.9328785336 159176.6964627999 234752.14429327767 162309.6370417804 176022.30087963774 0.8813861509778896 0.8146989488013543 0.6819000103583127 0.7576121097308938 0.7848944347149155 0.6479913755730718 0.9042984648385168 1.3336500154818383 0.9220970083374043 1.0 17.425398694948797 -7.528515681310619 24.954650047534333 1.1005190424000246 0.7623685076803036 0.6118956687006063 0.11544677273066815 88.93801396867171 393719.2893742839 0.05094205074343069 0.029525253862537265 2.9613130376992207e-08 7.528515681310619 -0.338150534719721 KSSVNGS(ph)SATSSG ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSSVNGSSATSSG 13 1 R4GMX3;P35226 R4GMX3 COMMD3-BMI1;BMI1 Polycomb complex protein BMI-1 1 KS(0.014)S(0.014)VNGS(0.486)S(0.486)ATSSG 81.565 0.016881999999999998 18100000.0 8362.5 7189.1 10870.0 8269.3 17794.0 17438.0 17684.0 18678.0 21516.0 15026.0 True False 9778.106083096289 7902.7863368932885 11129.182024704567 7805.997930432323 14307.393435297783 16523.52058215544 16008.84349892716 18187.722290976864 21830.630795727116 17750.09485424945 0.5508762721206173 0.4452250200229959 0.6269928198180975 0.439772181192797 0.8060460269524999 0.9308975933838256 0.901901856321324 1.0246549351043408 1.2298881203162002 1.0 14.115539113766186 -6.689651161898252 1.0189831949022634 1.0763007950263757 0.4948187411670117 0.8624234628844142 0.09458360575761979 0.1778206716908609 0.3973691539213319 0.05134047540500167 0.050232328327263404 2.0433785874582953e-07 6.689651161898252 -0.5814820538593639 KSSVNGSSATS(ph)SG ddPTM_PC-9_AZD4547_30min_R2 1 KSSVNGSSATSSG 13 1 R4GMX3;P35226 R4GMX3 COMMD3-BMI1;BMI1 Polycomb complex protein BMI-1 1 KS(0.235)S(0.235)VNGS(0.169)S(0.028)AT(0.049)S(0.25)S(0.033)G 72.243 0.035314 40246000.0 18976.0 17036.0 18313.0 27154.0 20088.0 20584.0 16544.0 21877.0 19091.0 18514.0 True False 25009.973274680236 22542.553842862584 18070.157654498355 20894.06482511795 17299.127944119948 19296.879226019995 18016.383950025272 18496.41233344812 20100.11128495104 17865.83049522303 1.3998774521770714 1.2617691547499021 1.0114367568487768 1.1694986600653472 0.9682800891201444 1.0800997597721305 1.00842689371997 1.0352954114500132 1.1250588821116048 1.0 14.124915358879361 -5.047380096265698 2.638250267814895 1.0511143831767389 1.4026067318395634 0.7919596067239476 0.05935778101996248 0.12543967565660566 1.5722130287838894 0.014930407794748659 0.07437438967671856 8.966437048412221e-06 5.047380096265698 0.3514923486628245 KSTGSPT(ph)QETQAPFIAK ddPTM_PC-9_AZD4547_30min_R2 1 KSTGSPTQETQAPFIAK 17 1 O15231-3;O15231-2 O15231-3 ZNF185 Zinc finger protein 185 1 KS(0.051)T(0.004)GS(0.051)PT(0.895)QETQAPFIAK 119.37 8.481700000000001e-05 39067000.0 87992.0 50585.0 91439.0 191050.0 156140.0 105260.0 104020.0 132100.0 94894.0 118510.0 True False 115971.62565270146 66935.61200641014 90226.45911481878 147006.37419307613 134462.6561725849 98678.07556018564 113277.5784865587 111686.98035601301 99909.90311005949 114361.00097163669 1.0140836882099715 0.5853010330244592 0.7889617819731776 1.2854589671660535 1.1757736905952207 0.8628647416671295 0.9905262941398467 0.9766177228871328 0.8736361369802866 1.0 16.803235627102374 -5.567949833128813 24.998887204401406 1.0221093161226897 0.7715513768553268 0.31086830008379385 0.1540895210388232 139.17676843047929 77194.38143012264 0.04289105875449277 0.0742895389191057 2.704270725816291e-06 5.567949833128813 -0.2505579392673629 KSVAAEGALLPQT(ph)PPSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSVAAEGALLPQTPPSPR 18 1 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 KSVAAEGALLPQT(0.83)PPS(0.17)PR 65.833 0.012361 9675400.0 40724.0 35346.0 40102.0 44606.0 51122.0 43725.0 43000.0 50773.0 44903.0 41433.0 True False 47617.76886433638 38854.917286423915 41058.1837676819 42106.8704346032 41105.011082347635 41431.98402653667 38926.728706959286 49440.262548440296 45559.621426869955 48944.47491655245 0.9728936503154232 0.7938570666590937 0.8388726988630233 0.8602987468226603 0.8398294424943642 0.8465099298169171 0.7953242684353474 1.0101295934369128 0.9308429910535668 1.0 15.578858390341116 -7.76663259889064 24.999997280868946 0.9778647424200138 0.8470048167773784 0.5850813880250134 0.05037877555544319 87.65518000629388 421959.1557050237 0.025104267293655683 0.01263468956777888 1.711462552784663e-08 7.76663259889064 -0.13085992564263538 KSVAAEGALLPQTPPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 KSVAAEGALLPQTPPSPR 18 1 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 KSVAAEGALLPQT(0.043)PPS(0.957)PR;KSVAAEGALLPQT(0.365)PPS(0.635)PR 89.10700000000001 0.00067559 26892000.0 96372.0 106745.0 153300.0 196016.0 151292.0 136594.0 128384.0 153237.0 125571.0 118872.0 True False 127016.29133787335 141248.23373775344 151267.14183555945 150827.53961701124 130287.71729001394 128052.75558681392 139809.92728723705 129557.742685953 132208.42670172258 114710.32746182097 1.1072786047110552 1.2313471407774081 1.3186880831275256 1.3148558020393688 1.1357976232207827 1.1163140967358298 1.2188085447996824 1.1294339886622127 1.152541620506885 1.0 16.807635758617337 -6.287151316403349 23.420708224165573 1.136162178987169 1.2476102859222669 0.3681480277513395 0.07457189892280053 404.1965546705613 368176.40417295555 0.02353703454322798 0.026700673644098727 5.162364713932267e-07 6.287151316403349 0.11144810693509788 KSVAAEGALLPQTPPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSVAAEGALLPQTPPSPR 18 1 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 KSVAAEGALLPQT(0.006)PPS(0.994)PR 93.551 0.00046973 8173800.0 38468.0 36066.0 48581.0 47359.0 50692.0 47311.0 51454.0 41206.0 47096.0 49502.0 True False 44979.87262236749 39646.394128109656 49739.355284468504 44705.62876994964 40759.26649556678 44829.92787374451 46579.904625299605 40124.3861613659 47784.68990312155 58476.32074238364 0.7691980625888809 0.6779905716498669 0.8505896857566385 0.7645082351692314 0.6970217342354862 0.7666338665738212 0.7965601124343393 0.6861646843024402 0.8171630721029136 1.0 15.83556492111166 -8.547199494927277 18.58186299554202 1.0000000017731874 0.7525822017928859 0.6909748070431865 0.050216982597387126 87.30592752314129 66705.38357736828 0.047125587953783805 0.012167773221940677 2.8366157182178704e-09 8.547199494927277 -0.24741779998030144 KSVAAEGALLPQTPPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 KSVAAEGALLPQTPPSPR 18 1 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 KSVAAEGALLPQT(0.081)PPS(0.919)PR;KSVAAEGALLPQT(0.37)PPS(0.63)PR 102.46 0.00021219999999999998 19053700.0 130834.0 119423.0 110589.0 89940.0 96066.0 118647.0 101764.0 80601.0 118839.0 86199.0 True False 128968.2831679826 119146.4833808274 101496.79930588478 96554.48763104473 90415.5867530228 113572.74438966578 107032.84198492387 84346.01670841682 105454.10038985158 101098.38229705207 1.2756710862993026 1.1785201768189084 1.003940884114862 0.9550547242916682 0.8943326757431135 1.1233883451859887 1.0586998481383696 0.8342964030877106 1.0430839543999955 1.0 16.62540038690333 -5.137172035149748 2.5144137558710082 0.9837509209659528 1.2710352691625182 0.6116986474265876 0.07772546579920041 0.21176003841885122 2.436055236345054 0.02158733378157053 0.0912164959450522 7.291686107056219e-06 5.137172035149748 0.28728434819656534 KSVQPTSEER ddPTM_PC-9_AZD4547_30min_R2 1 KSVQPTSEER 10 1 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;Q9UHD8-8;Q9UHD8-3;Q9UHD8-9;K7EL40;Q9UHD8-4;K7ER52;K7EK18;K7EQD7;K7ER14;K7EIR4;K7EIE4;K7ELJ9;K7EJZ2;K7ENQ5;K7EN52;K7EKN4 Q9UHD8 SEPT9 Septin-9 0 67.207 0.027968 1798800.0 6299.2 4457.2 7893.5 12276.0 8608.3 6470.7 5134.9 7579.7 6089.9 5946.8 False True 8302.214568500513 5897.902734703404 7788.827032478723 9445.95786230935 7413.186135074069 6066.086106092477 5591.896152380608 6408.4315291784405 6411.79968122274 5738.604342065044 1.4467306114212695 1.0277590827216774 1.3572685217876344 1.6460374856424078 1.2918099407436103 1.0570664476076406 0.9744348658768758 1.116723012632782 1.117309941412592 1.0 12.486484193408083 -6.708093567476697 4.668993525130365 1.0544422299540195 1.357192978742755 0.5125123476006924 0.14771802113951754 0.19052775613938674 8.628429923598638 0.05376105956414515 0.05245320247871415 1.9584226916057416e-07 6.708093567476697 0.30275074878873554 KSVSS(ph)PTSSNTPTPTK ddPTM_PC-9_AZD4547_30min_R2 2 KSVSSPTSSNTPTPTK 16 1 Q5M775;Q5M775-4;Q5M775-2;Q5M775-5;Q5M775-3 Q5M775 SPECC1 Cytospin-B 1 KS(0.029)VS(0.112)S(0.486)PT(0.12)S(0.182)S(0.029)NT(0.039)PT(0.002)PTK;KS(0.02)VS(0.146)S(0.668)PT(0.034)S(0.052)S(0.079)NT(0.001)PTPTK 89.65899999999999 0.0016966999999999998 24653000.0 86331.0 76475.0 97657.0 157482.0 138297.0 137649.0 113626.0 140886.0 110329.0 129670.0 True False 113782.46220364748 101194.04819986591 96362.00437204976 121176.95797264583 119096.84872998596 129041.78627003601 123738.49387727125 119115.30593820762 116160.76569888233 125130.29276847647 0.909311883527473 0.8087094336708791 0.7700933342363746 0.9684062531273275 0.9517827066092305 1.0312593650587618 0.9888772026308577 0.9519302105254549 0.9283185000918195 1.0 16.933071567988314 -5.777856198608333 24.312430934858366 0.9743988964819799 0.8273053664301362 0.7147142425469678 0.04197367885011993 88.15823986398108 130557.38068297658 0.012215382413006697 0.018183575133550706 1.6677993544193183e-06 5.777856198608333 -0.14709353005184367 KSVSS(ph)PTSSNTPTPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KSVSSPTSSNTPTPTK 16 1 Q5M775;Q5M775-4;Q5M775-2;Q5M775-5;Q5M775-3 Q5M775 SPECC1 Cytospin-B 1 KS(0.041)VS(0.152)S(0.786)PT(0.015)S(0.003)S(0.003)NTPTPTK 65.855 0.012714 9228600.0 70460.0 61303.0 58613.0 56089.0 66580.0 45332.0 30349.0 61337.0 31228.0 25442.0 True False 82387.48635156528 67388.75670258718 60010.55621104032 52946.515172991516 53534.126948529134 42954.71011757489 27474.12301226761 59726.968741923534 31684.650422428243 30054.433201238822 2.7412756647218797 2.242223509968222 1.9967289287813528 1.7616873630080336 1.7812389470157266 1.4292304176877415 0.9141454383220624 1.9872931338283109 1.0542421549018675 1.0 14.875290191973892 -1.5228787452812989 0.2665034419782285 1.1133209153666532 12.49180756784216 0.753809531671649 0.27875604944187926 25.36922690687729 0.35290798663193934 0.3259164560409761 132.1870859310468 0.029999999999933597 1.5228787452812989 11.378486652475507 up KSVSS(ph)PTSSNTPTPTK ddPTM_PC-9_Lapatinib_30min_R1 3 KSVSSPTSSNTPTPTK 16 1 Q5M775;Q5M775-4;Q5M775-2;Q5M775-5;Q5M775-3 Q5M775 SPECC1 Cytospin-B 1 KS(0.031)VS(0.046)S(0.864)PT(0.023)S(0.035)SNTPTPTK;KS(0.184)VS(0.179)S(0.577)PT(0.043)S(0.014)S(0.001)NT(0.001)PTPTK;KS(0.025)VS(0.093)S(0.368)PT(0.36)S(0.119)S(0.033)NT(0.001)PT(0.001)PTK 103.41 0.00062693 28309500.0 141067.0 124727.0 151133.0 135999.0 140139.0 113697.0 119715.0 127671.0 155230.0 132641.0 True False 139055.3587114807 124438.20229470427 138707.42813025127 146000.82013936443 131896.29954387475 108834.44435065202 125913.25693000611 133603.0607458998 137746.36275563305 155567.82011697683 0.8938568311037601 0.7998968051434729 0.8916203108454714 0.938502705955392 0.8478379361792006 0.6995948408148653 0.8093785516524405 0.8588091074711919 0.8854425205164975 1.0 17.247184137852123 -8.691656407653007 1.9217010514176966 0.9996178916482994 0.8398521023946847 0.37499648984737133 0.06151643150488727 0.7492355573181761 5.334803513692262 0.06455323737500152 0.01801780519088455 2.033965547651378e-09 8.691656407653007 -0.15976578925361473 KSYES(ph)SEDCSEAAGSPAR ddPTM_PC-9_Lapatinib_30min_R1 1 KSYESSEDCSEAAGSPAR 18 1 Q6P6C2-3;Q6P6C2;K7ER58 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 KS(0.002)YES(0.965)S(0.031)EDCS(0.002)EAAGSPAR 108.17 0.0011888 0.0 4725.7 3256.2 4845.0 4091.1 5334.4 4700.7 4410.0 3333.1 4749.6 2171.6 True False 4658.310651412755 3248.660468960331 4446.662802240848 4391.973141509525 5020.641079833914 4499.662018866901 4638.328221704279 3487.9679940797796 4214.650032494714 2546.958166524887 1.8289702252034368 1.2755060179857052 1.7458719427292164 1.7243994028775147 1.971230287886574 1.7666807715991333 1.8211246194250974 1.3694641867003345 1.6547778789179148 1.0 11.314559548379915 -9.025154930825313 0.851933384652605 0.998969413819722 1.7133119555257454 0.5305882753822947 0.19650614215489023 1.4068712549125817 1.5978840226928805 0.20711634669369447 0.0670530012258991 9.43724150744458e-10 9.025154930825313 0.7143425417060234 KSYESSEDCS(ph)EAAGSPAR ddPTM_PC-9_AZD4547_30min_R2 1 KSYESSEDCSEAAGSPAR 18 1 Q6P6C2-3;Q6P6C2;K7ER58 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 KSYESSEDCS(0.652)EAAGS(0.348)PAR 101.53 0.00076374 4616100.0 6031.3 5256.3 7584.1 12032.0 10652.0 10011.0 6438.5 9175.6 6801.5 8808.6 True False 7949.127941166675 6955.2961824512 7483.529878637088 9258.208292546926 9173.15366690391 9385.010587431309 7011.514026972788 7757.7218543121335 7161.01340446255 8500.213595129177 0.9351680228037696 0.818249577450236 0.8803931565820096 1.0891736059258674 1.0791674308231907 1.104091148110577 0.8248632753170522 0.912650225490509 0.8424509954156894 1.0 13.053283378707947 -10.81295100268403 14.391586871357587 0.9999999922298379 0.9460944333371532 0.02507868285911763 0.10510987417768891 0.0 0.0 0.11257371637363754 0.02730313666334306 1.5383281854517862e-11 10.81295100268403 -0.05390555889268478 KSYESSEDCSEAAGS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 3 KSYESSEDCSEAAGSPAR 18 1 Q6P6C2-3;Q6P6C2;K7ER58 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 KSYESSEDCSEAAGS(1)PAR;KSYESSEDCS(0.004)EAAGS(0.996)PAR;KSYESSEDCSEAAGS(1)PAR 138.09 5.2306000000000004e-05 72384000.0 70130.0 72671.0 93238.0 123106.0 116075.0 90242.0 84060.0 104361.0 69598.0 98010.0 True False 92429.88120538164 96160.47959114035 92001.60319937313 94725.81366874016 99959.98985034456 84599.15347427581 91541.17715420222 88234.40542720593 73276.808192867 94578.6997319224 0.9772801007771151 1.0167244830358357 0.9727518295361017 1.001555465842042 1.0568974846733472 0.894484209595469 0.9678836504801837 0.9329204744546183 0.7747707295677111 1.0 16.52922768730835 -7.192530158764196 1.3380630716777684 0.8975320903209113 1.0009146370928557 0.2904306665840175 0.06291825370851331 0.5315756087153412 1.8753604981465968 0.03657745788797533 0.022556210184588428 6.419036441679158e-08 7.192530158764196 0.10338254677194436 KSYESSEDCSEAAGS(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 KSYESSEDCSEAAGSPAR 18 1 Q6P6C2-3;Q6P6C2;K7ER58 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 KSYESSEDCS(0.029)EAAGS(0.971)PAR;KSYESSEDCSEAAGS(1)PAR;KSYESSEDCSEAAGS(1)PAR;KSYESSEDCSEAAGS(1)PAR 165.9 6.2248e-08 67046000.0 78854.0 67991.0 92544.0 100244.0 107525.0 93946.0 94885.0 98653.0 99044.0 77566.0 True False 92202.42476250819 74740.69714313486 94750.5999350745 94627.65367543277 86456.24812467108 89019.30637751892 85896.80589208918 96063.46328149374 100492.33112716094 91628.10178788168 1.0062679785286404 0.8156962294838213 1.0340779530107627 1.0327361565832176 0.943556031803612 0.9715284354967639 0.9374504569672261 1.0484061265819944 1.0967413835528306 1.0 16.48350251163084 -7.778567086433965 17.739374424415292 1.0544336163317174 0.9623668920816603 0.2782199016632022 0.0627549269402007 10.727191720953423 11104.257444333954 0.03404800780590819 0.01654859998344741 1.6650716006070593e-08 7.778567086433965 -0.09206672425005713 KSYESSEDCSEAAGS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 6 KSYESSEDCSEAAGSPAR 18 1 Q6P6C2-3;Q6P6C2;K7ER58 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 KSYESSEDCSEAAGS(1)PAR;KSYESSEDCSEAAGS(1)PAR;KSYESSEDCSEAAGS(1)PAR;KSYESSEDCSEAAGS(1)PAR;KSYESSEDCSEAAGS(1)PAR;KSYESSEDCSEAAGS(1)PAR 129.75 4.408e-05 99210400.0 103747.0 102881.1 143779.7 107513.3 121528.3 109874.3 94395.6 87625.79999999999 122164.4 85251.8 True False 102267.54875513047 102642.88513394579 131958.68807169184 115420.18673585507 114380.24432783078 105175.23231850326 99282.94228678194 91697.21456171015 108404.95882383718 99987.460039117 1.022803746741056 1.0265575812585892 1.3197523771487654 1.1543466219734004 1.1439458936458937 1.0518842290558907 0.9929539389033442 0.9170871479867221 1.084185544681574 1.0 16.60945954969884 -6.948026884896448 2.902542431646424 0.9927408513053328 1.1393576856226069 0.3548879567672516 0.08568291746074673 0.3021680241258638 5.179999135887716 0.035652441080521464 0.02976943878690002 1.1271276794452758e-07 6.948026884896448 0.14661683431727401 KT(ph)ASFGNILDVPEIVISGNGQPR ddPTM_PC-9_AZD4547_30min_R2 1 KTASFGNILDVPEIVISGNGQPR 23 1 O43318-3;O43318 O43318-3 MAP3K7 Mitogen-activated protein kinase kinase kinase 7 1 KT(0.5)AS(0.5)FGNILDVPEIVISGNGQPR 81.904 0.00010295 1149600.0 5387.2 3998.9 6112.0 9069.1 6423.4 6198.3 5545.9 8081.4 4689.8 6710.9 True False 7100.217539278951 5291.466222248372 6030.95088649014 6978.359111198246 5531.621785954807 5810.7193211542835 6039.47435616811 6832.605322097533 4937.693253583543 6475.953433638986 1.0963972505418675 0.8170945446831257 0.9312838562369358 1.0775801868724906 0.8541787464408098 0.8972762668383036 0.9326000284060707 1.0550732632828916 0.7624658367577144 1.0 12.660876896414418 -4.7326148274360404 24.39416152976056 0.9290828414538637 1.0963985372970337 0.22582098984414345 0.09481371429816947 3845.908436860429 3254545.930072131 0.022635176552052064 2.2900933833662993 1.8509094491515847e-05 4.7326148274360404 0.16731569584317008 KT(ph)ASFGNILDVPEIVISGNGQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KTASFGNILDVPEIVISGNGQPR 23 1 O43318-3;O43318 O43318-3 MAP3K7 Mitogen-activated protein kinase kinase kinase 7 1 KT(0.5)AS(0.5)FGNILDVPEIVISGNGQPR;KT(0.5)AS(0.5)FGNILDVPEIVISGNGQPR;KT(0.5)AS(0.5)FGNILDVPEIVISGNGQPR 66.828 0.0013264000000000001 25206600.0 137062.6 127000.2 120914.0 173018.0 158858.3 151967.5 146541.0 137966.6 133272.6 123681.5 True False 160264.59107025305 139607.94054091795 123797.04832889875 163324.3623919243 127731.15648884854 143998.05677650592 132659.57561503517 134345.12293769603 135221.4596480115 146103.9768877848 1.096921483481208 0.9555382646985978 0.847321551171609 1.117863906725589 0.8742483210224489 0.9855861547636288 0.9079805932792944 0.9195172219088863 0.9255152565208296 1.0 17.15663592265488 KT(ph)ASFGNILDVPEIVISGNGQPR ddPTM_PC-9_Lapatinib_30min_R1 1 KTASFGNILDVPEIVISGNGQPR 23 1 O43318-3;O43318 O43318-3 MAP3K7 Mitogen-activated protein kinase kinase kinase 7 1 KT(0.5)AS(0.5)FGNILDVPEIVISGNGQPR 78.942 0.0025588 0.0 4211.0 3476.8 2551.3 2779.1 2782.9 3158.3 2803.7 1035.6 2990.5 2497.4 True False 4150.950367797176 3468.749683213956 2341.541962302802 2983.484284805828 2619.215293391909 3023.2268713568897 2948.8618673905416 1083.7177566436703 2653.6783986389255 2929.072262423676 1.417155329709227 1.1842485853673412 0.7994142009884321 1.0185765380664007 0.8942132725754693 1.0321448569709595 1.00675627065291 0.3699866918772917 0.9059791500135697 1.0 11.516228070694073 -1.5228790822081355 0.5964673359248716 0.8354969400268488 37.62289550156322 0.4509235447696329 0.18931989193240564 154.6109193689368 1.2130293935150849 0.08896857903802076 7404.763623336722 0.02999997672586128 1.5228790822081355 36.78739856153637 KT(ph)GSPGSPGAGGVQSTAK ddPTM_PC-9_AZD4547_30min_R2 1 KTGSPGSPGAGGVQSTAK 18 1 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 KT(0.476)GS(0.476)PGS(0.048)PGAGGVQSTAK 62.658 0.017112 2016600.0 7594.1 8934.9 10006.0 11538.0 12703.0 9577.0 8670.1 11349.0 9337.0 11725.0 True False 10008.865832907315 11822.931693507446 9873.313902195747 8878.092360323008 10939.407719740935 8978.148676039322 9441.722103790757 9595.272824075637 9830.534758136702 11314.511318812245 0.8846043413528538 1.0449352482285177 0.8726239803021568 0.7846642342883791 0.9668475651752066 0.7935074191946466 0.8344790011471669 0.8480501325869824 0.8688430707380012 1.0 13.465886654551866 -5.4178303949981474 8.914243505124107 0.8611724698184758 0.9643004689515945 0.1964283985446339 0.0739413250776019 0.4353956193013527 33.86868875251644 0.018019028942312623 0.03758294555050341 3.82093460646292e-06 5.4178303949981474 0.10312799913311865 KT(ph)GSPGSPGAGGVQSTAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KTGSPGSPGAGGVQSTAK 18 1 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 KT(0.485)GS(0.103)PGS(0.411)PGAGGVQSTAK 87.509 0.0013882 5745400.0 32417.0 20077.0 25267.0 28932.0 36627.0 34324.0 34559.0 29278.0 26191.0 24917.0 True False 37904.55783506514 22070.11187572943 25869.46110563111 27311.033838809577 29450.202279119476 32523.989016051368 31285.321334507105 28509.48352260523 26573.993826496022 29434.25485713654 1.2877702533677327 0.7498104498602036 0.8788896213337937 0.9278656440045 1.000541798053334 1.1049706939724244 1.0628881718377103 0.9685817990290625 0.9028254309639155 1.0 14.845208485116842 -4.734773597141802 24.878274754800387 0.9604018468000426 1.2877720166217344 0.5245765343634383 0.0948769738752259 2448.60819270053 2284340.912664918 0.026010429011069404 2.1991205764617416 1.8417318678927844e-05 4.734773597141802 0.32737016982169176 KT(ph)GSYGALAEITASK ddPTM_PC-9_Lapatinib_30min_R1 1 KTGSYGALAEITASK 15 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 KT(0.767)GS(0.229)Y(0.004)GALAEITASK 89.917 0.0037215000000000004 2060000.0 17939.0 13481.0 17975.0 12032.0 13611.0 15264.0 14114.0 10315.0 14284.0 10724.0 True False 17683.186570390313 13449.785572770177 16497.164885506543 12916.873417575378 12810.427740255584 14611.194302121889 14844.753859667619 10794.272556758859 12675.185502811715 12577.629111168208 1.4059236771967354 1.0693418810408033 1.3116275523546814 1.0269720392777317 1.018508943699148 1.1616811223307573 1.1802505645906138 0.8582120256014044 1.0077563418972884 1.0 13.618572378720554 -1.5228787452899768 0.2934054595091588 0.9867465898016828 3.8002981231489605 0.4626499500639787 0.11316941389734447 51.8382098031149 0.7368604368814655 0.1200125441140788 75.96999174625685 0.029999999999334146 1.5228787452899768 2.813551533347278 KT(ph)NPGPVGET(ph)LLCQLS(ph)SY(ph)AK ddPTM_PC-9_AZD4547_30min_R2 1 KTNPGPVGETLLCQLSSYAK 20 1 H0YID1;F8VUX5;H0YIQ8;F8VXI8;F8VX10;Q9H9L4-4;Q9H9L4 H0YID1 KANSL2 KAT8 regulatory NSL complex subunit 2 4 KT(1)NPGPVGET(0.99)LLCQLS(0.821)S(0.368)Y(0.821)AK 45.916000000000004 0.040951 0.0 1969.5 2145.7 5871.2 6311.0 5421.4 3789.1 4233.7 5471.0 3721.0 5770.0 True False 2595.760031855117 2839.255563549558 5793.344051826071 4856.096453978029 4668.732190175825 3552.16697800779 4610.491098236338 4625.582661073031 3917.6844634279432 5567.994056251317 0.4661930321101541 0.5099243165250615 1.0404723843628656 0.8721446906944839 0.8384944637169881 0.6379617043627569 0.8280344863263697 0.8307448992119131 0.703607874550345 1.0 12.44294195579461 -5.153128778521744 7.347518425897288 0.8304094580068384 0.47942192557374297 0.6111148871848848 0.1132738474464362 0.17499444093287977 10.467661485027023 0.029240341905385162 0.07866686139014244 7.028638733218292e-06 5.153128778521744 -0.35098753243309544 KT(ph)PADT(ph)GDS(ph)GK ddPTM_PC-9_AZD4547_30min_R2 2 KTPADTGDSGK 11 1 M0QYV0 M0QYV0 3 KT(1)PADT(1)GDS(1)GK;KT(1)PADT(1)GDS(1)GK 97.631 0.019542 45788000.0 0.0 0.0 0.0 1472.6 1450.8 0.0 0.0 1588.8 0.0 0.0 True False 0.0 0.0 0.0 1133.1148214432008 1249.3814626308863 0.0 0.0 1343.287466991927 0.0 0.0 0.0 KT(ph)PADT(ph)GDS(ph)GK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KTPADTGDSGK 11 1 M0QYV0 M0QYV0 3 KT(1)PADT(1)GDS(1)GK 86.756 0.039538 11321000.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KT(ph)PELGIVPPPPIPR ddPTM_PC-9_AZD4547_30min_R2 2 KTPELGIVPPPPIPR 15 1 Q8TEH3;Q8TEH3-7;Q8TEH3-6 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 KT(1)PELGIVPPPPIPR;KT(1)PELGIVPPPPIPR 88.781 0.0040244 17455400.0 22489.0 23659.0 31032.0 39040.0 33543.0 30777.0 30304.0 42384.0 35807.0 32468.0 True False 29640.034199740938 31306.30907303864 30620.49540405141 30039.93116198736 28886.133444325747 28852.509324680195 33000.997293373184 35834.52668742812 37699.684918560684 31331.305202490075 0.9460197718601674 0.9992021995480275 0.9773131124335613 0.9587832670181872 0.9219575519640338 0.9208843722982573 1.0532914948832202 1.1437291378649668 1.2032593176349538 1.0 14.935317250437413 -7.496805960028975 3.660223195197396 1.1281480520625395 0.9564562534007411 0.6603988158890366 0.05236411480721559 0.1308674226549057 3.73440685943677 0.024798019053483687 0.014815983282657057 3.185620518493183e-08 7.496805960028975 -0.1716917986617984 KT(ph)PELGIVPPPPIPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KTPELGIVPPPPIPR 15 1 Q8TEH3;Q8TEH3-7;Q8TEH3-6 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 KT(1)PELGIVPPPPIPR 71.637 0.018059 5278600.0 13023.0 16808.0 17970.0 16927.0 21848.0 13792.0 18748.0 16086.0 9972.5 12994.0 True False 15227.536684025465 18476.5871597978 18398.472951604497 15978.63506807443 17567.041237180285 13068.723240571628 16972.053716234255 15663.759544525836 10118.328946383552 15349.70933955259 0.9920407186335239 1.2037092527992033 1.1986202829389063 1.0409731360125007 1.144454324741782 0.8513987432254891 1.1056921887440088 1.0204596841559737 0.6591870062523594 1.0 13.905923716685212 -7.105305157728239 0.7687471319062663 0.8862777411071548 1.1332259794268589 0.3121890958553436 0.13078757091366608 0.8052171303891609 0.9694907613352217 0.10175806054655548 0.07140938829222047 7.846840813043336e-08 7.105305157728239 0.24694823831970403 KT(ph)PELGIVPPPPIPR ddPTM_PC-9_Lapatinib_30min_R1 2 KTPELGIVPPPPIPR 15 1 Q8TEH3;Q8TEH3-7;Q8TEH3-6 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 KT(1)PELGIVPPPPIPR;KT(1)PELGIVPPPPIPR 89.26 0.0038968 15338600.0 18228.3 26355.0 25042.0 24580.0 27461.0 22224.0 20178.8 24690.0 20333.2 15321.7 True False 17968.36109933918 26293.976616746386 22983.14342491542 26387.69519647628 25845.797970403266 21273.53132667432 21223.55952837331 25837.187535276393 18043.060897911728 17970.035430118063 0.9999068265176553 1.4632122857519394 1.2789704012711798 1.4684275553653103 1.43827195393757 1.183833577257146 1.181052736980267 1.4377927987817352 1.0040637353263797 1.0 14.13330563284946 -8.277228917462919 24.038256513386344 1.002031665213066 1.3122724262000918 0.4119965531783222 0.14532832492588152 532.1213786616267 810097.7691197969 0.13489296307047516 0.03536981181546007 5.281667806568118e-09 8.277228917462919 0.3102407609870257 KT(ph)PQGPPEIYSDTQFPSLQSTAK ddPTM_PC-9_AZD4547_30min_R2 2 KTPQGPPEIYSDTQFPSLQSTAK 23 1 D6R9V8;Q9UKY7;D6RFH2;D6RDN0;H0Y8K3;Q9UKY7-3;Q9UKY7-2 D6R9V8 CDV3 Protein CDV3 homolog 1 KT(0.896)PQGPPEIY(0.103)S(0.001)DTQFPSLQSTAK;KT(1)PQGPPEIYSDTQFPSLQSTAK 136.46 5.125800000000001e-07 26235000.0 59738.0 64485.0 76940.0 103742.0 93351.0 99157.0 89114.0 110954.0 96428.0 95584.0 True False 78733.44137240964 85328.51517709532 75919.72532829714 79825.88469792252 80390.82500555251 92956.69711496604 97044.97336330706 93808.60876927359 101524.98721833644 92237.63325350513 0.8535934693382614 0.9250943694812631 0.8230883929950805 0.8654372611505515 0.8715620964016613 1.007795775282792 1.0521190748313052 1.0170318281199908 1.1006894218470027 1.0 16.493067874572553 -6.818765587575453 3.5816285747376537 1.0425239528117545 0.8669230049009922 0.8607516196549276 0.03394868376792696 0.07942443270619842 2.0655569168817203 0.012002933561597982 0.010812288235439952 1.517869423329071e-07 6.818765587575453 -0.1756009479107623 KT(ph)PQGPPEIYSDTQFPSLQSTAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KTPQGPPEIYSDTQFPSLQSTAK 23 1 D6R9V8;Q9UKY7;D6RFH2;D6RDN0;H0Y8K3;Q9UKY7-3;Q9UKY7-2 D6R9V8 CDV3 Protein CDV3 homolog 1 KT(0.935)PQGPPEIY(0.034)S(0.023)DT(0.008)QFPSLQSTAK 104.18 1.0227e-05 7129100.0 39278.0 46258.0 42874.0 41446.0 55028.0 41205.0 46808.0 40351.0 37477.0 35727.0 True False 45926.98962413822 50850.188531528256 43896.278760550435 39123.914989744975 44245.65842180326 39044.13726274318 42374.00737942673 39291.82900541851 38025.03022548171 42204.0222852236 1.0882135667959332 1.204865929315269 1.0400970425020206 0.9270186316682658 1.048375392344878 0.9251283443761531 1.0040276989016435 0.9309972575570197 0.9009811900984369 1.0 15.365092882140916 -5.493728054029159 4.532330682898667 0.9638717326456586 1.1445824066657668 0.6829777951135739 0.049958546455450184 0.10491975270356385 5.1597456897610074 0.012953439795958017 0.026482706755443623 3.2082776509065877e-06 5.493728054029159 0.1807106740201082 KT(ph)PQGPPEIYSDTQFPSLQSTAK ddPTM_PC-9_Lapatinib_30min_R1 1 KTPQGPPEIYSDTQFPSLQSTAK 23 1 D6R9V8;Q9UKY7;D6RFH2;D6RDN0;H0Y8K3;Q9UKY7-3;Q9UKY7-2 D6R9V8 CDV3 Protein CDV3 homolog 1 KT(1)PQGPPEIYSDTQFPSLQSTAK 133.92 1.1923e-06 7924900.0 38771.0 38811.0 46906.0 46283.0 44829.0 40027.0 40290.0 35372.0 42547.0 33830.0 True False 38218.118430269395 38721.135514040725 43049.569742396096 49686.80621556192 42192.24635720505 38315.13851749432 42376.01905951596 37015.51225183463 37754.908820227516 39677.4704243585 0.9632196312294851 0.975897281250806 1.0849877596019182 1.2522674879258069 1.063380450062731 0.9656648497927472 1.0680121138342726 0.9329100836304913 0.9515452577100102 1.0 15.276032431419344 -6.711403104631736 6.991125542353529 0.9847640833326763 1.0745658492552081 0.21243108551807632 0.08076076705811673 0.3679592312028321 40.46187905987063 0.02976318488413854 0.029503178044971153 1.9435552697457663e-07 6.711403104631736 0.08980176592253186 KT(ph)QGNT(ph)MT(ph)FIY(ph)REK ddPTM_PC-9_Lapatinib_30min_R1 1 KTQGNTMTFIYREK 14 2 A0JD36 A0JD36 hDV102S1 4 KT(1)QGNT(1)MT(1)FIY(1)REK 52.784 0.041000999999999996 0.0 3506.3 3520.1 2497.0 3769.9 2219.9 2836.7 2158.8 2567.9 2772.9 1047.9 True False 3456.299519023329 3511.9494247242997 2291.7062986987394 4047.151022017738 2089.3298464913228 2715.3809536706754 2270.5721009104764 2687.214008579839 2460.5868020685093 1229.028118761019 2.8122216784654355 2.857501281797108 1.8646492002225339 3.292968614987966 1.6999853905682585 2.209372521442427 1.8474533383332483 2.186454457436511 2.0020589964605713 1.0 10.263302207966651 -7.839341242053591 0.10752220826514546 1.6644532646001652e-12 3.959310547049958 0.5535175130491334 0.4206303774058411 6.6281340362845595 0.7211976647170177 11.842215517786641 12.485681322629036 1.4476339443002022e-08 7.839341242053591 3.9593105470482937 KT(ph)QLEQEAGK ddPTM_PC-9_AZD4547_30min_R2 1 KTQLEQEAGK 10 1 Q9H4T2 Q9H4T2 ZSCAN16 Zinc finger and SCAN domain-containing protein 16 1 KT(1)QLEQEAGK 72.643 0.025491 11718000.0 52487.0 42250.0 53102.0 74998.0 59962.0 56631.0 82793.0 102970.0 103720.0 91144.0 True False 69176.7742025792 55906.48625621882 52397.83278376958 57708.36980754939 51637.3113194604 53089.8546176029 90161.41660870652 87058.35251520573 109202.42745142318 87953.07630207427 0.7865190975809875 0.6356399185425687 0.5957475848122648 0.6561267920788849 0.5871006847118387 0.6036156647354338 1.025108164483613 0.9898272598925861 1.2415987256246517 1.0 16.424446418737645 -7.303087046883175 5.0385532955455785 1.0695347766373704 0.6389312809870641 0.858486631440343 0.0835899445741918 0.07192236310043279 4.522822148108739 0.03521081355165383 0.02388575266809171 4.976373321108702e-08 7.303087046883175 -0.4306034956503063 KT(ph)SASDVTNIYPGDAGK ddPTM_PC-9_AZD4547_30min_R2 1 KTSASDVTNIYPGDAGK 17 1 Q15042-4;Q15042;Q15042-3 Q15042-4 RAB3GAP1 Rab3 GTPase-activating protein catalytic subunit 1 KT(0.333)S(0.333)AS(0.333)DVT(0.001)NIYPGDAGK 81.574 0.004254699999999999 28651000.0 104430.0 106980.0 124250.0 130500.0 136600.0 144720.0 112540.0 136130.0 119130.0 115550.0 True False 137636.567721061 141559.192892078 122602.36381649211 100415.24120490131 117635.44788763372 135670.6355222312 122555.84198113187 115094.23645620047 125426.96859128473 111504.62967068255 1.2343574264813617 1.2695364605950308 1.0995271154084416 0.9005477306320588 1.0549826337709736 1.2167264796351547 1.0991098965405108 1.032192446144339 1.1248588418411 1.0 16.76674408650412 -5.322154039486383 5.087971077867737 1.0659778132352555 1.2522064970134466 0.4769489246097315 0.07834302737171635 0.17730573108589553 9.48622989368488 0.02209069031370618 0.04868461483441588 4.7626203192818e-06 5.322154039486383 0.18622868377819102 KT(ph)SASDVTNIYPGDAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KTSASDVTNIYPGDAGK 17 1 Q15042-4;Q15042;Q15042-3 Q15042-4 RAB3GAP1 Rab3 GTPase-activating protein catalytic subunit 1 KT(0.327)S(0.327)AS(0.327)DVT(0.02)NIYPGDAGK 96.435 0.0013179 8591000.0 43936.0 44994.0 63390.0 62489.0 84247.0 105790.0 149480.0 123810.0 117500.0 112220.0 True False 51373.49702444463 49460.70696501322 64901.45800791371 58987.94392207148 67739.40512214991 100242.18616734853 135320.17225851782 120560.11868753874 119218.21521183917 132564.59766696856 0.38753557079776424 0.37310645402680886 0.4895836380913738 0.4449750910892678 0.5109916698297249 0.7561761430391767 1.0207866552612475 0.9094443072230513 0.8993216689069699 1.0 17.01633601919624 -6.8533954596622655 2.1396541336232175 0.9515158224742488 0.42606950845301406 0.962648165717079 0.048311009927278534 0.056545558979372544 0.5300765301415848 0.02047593633020402 0.017730289498733325 1.4015369125262645e-07 6.8533954596622655 -0.5254463140212348 down KT(ph)SASDVTNIYPGDAGK ddPTM_PC-9_Lapatinib_30min_R1 2 KTSASDVTNIYPGDAGK 17 1 Q15042-4;Q15042;Q15042-3 Q15042-4 RAB3GAP1 Rab3 GTPase-activating protein catalytic subunit 1 KT(0.371)S(0.371)AS(0.176)DVT(0.082)NIYPGDAGK;KT(0.333)S(0.333)AS(0.333)DVTNIYPGDAGK 112.57 0.00021355 28470000.0 129060.0 143923.0 145524.0 162496.0 277760.0 339800.0 390010.0 363680.0 342700.0 271620.0 True False 127219.58073329448 143589.75513610308 133559.5784588848 174446.49791076532 261422.70289717065 325267.5461124886 410202.80946641427 380577.90047911386 304101.51720901486 318569.1550890998 0.39934682533126215 0.45073338972802574 0.41924830551008574 0.5475938116544109 0.8206152376053294 1.021026489590668 1.2876413265800504 1.1946476750791237 0.954585565962786 1.0 18.28124706159435 -6.442412366272396 1.6469996544831287 1.1275761255138963 0.4242582915114637 0.9163972046655917 0.0912970922847137 0.09752357910743628 0.5314651576325429 0.03604050262037013 0.042053024403665845 3.6106686379366483e-07 6.442412366272396 -0.7033178340024326 down KT(ph)SDANETEDHLESLICK ddPTM_PC-9_AZD4547_30min_R2 1 KTSDANETEDHLESLICK 18 1 F2Z2T1;Q09161 F2Z2T1 NCBP1 Nuclear cap-binding protein subunit 1 1 KT(0.333)S(0.333)DANET(0.333)EDHLESLICK 65.298 0.039652999999999994 77323000.0 91526.0 99641.0 114370.0 126400.0 106540.0 140490.0 118170.0 144280.0 135280.0 113660.0 True False 120629.36414093511 131848.00466404506 112853.37907196967 97260.43286053285 91748.7600142643 131705.13809092224 128686.90107437636 121984.84122456925 142430.62462040648 109680.79799541128 1.099822086870501 1.2021065407416271 1.028925583461666 0.8867589827765653 0.8365070430842672 1.2008039738772907 1.1732856017309452 1.112180467812358 1.298592162197483 1.0 16.742951447200454 -6.827914122115027 24.999999999968743 1.1650037724925484 1.0155548890086636 0.27455794534629585 0.1182966414765142 82.56416105448068 31049.65928296508 0.04493806751196982 0.03963166308171158 1.4862295019446592e-07 6.827914122115027 -0.14944888348388474 KT(ph)SDANETEDHLESLICK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KTSDANETEDHLESLICK 18 1 F2Z2T1;Q09161 F2Z2T1 NCBP1 Nuclear cap-binding protein subunit 1 1 KT(0.494)S(0.494)DANET(0.012)EDHLESLICK 71.402 0.007690100000000001 23349000.0 42654.0 58509.0 47089.0 67191.0 83850.0 76213.0 107110.0 93530.0 85514.0 72220.0 True False 49874.47974509884 64317.38684748985 48211.780346026986 63426.50610616115 67420.19442226137 72216.2561146813 96963.76539075372 91074.93660322634 86764.48047340628 85312.91430679444 0.5846064473397876 0.7538997743787955 0.5651170252214363 0.7434572669510807 0.7902695033932504 0.8464868033341805 1.1365660894206657 1.067539860093292 1.0170146123644523 1.0 16.380476526674798 -6.811879946053315 1.4350388266600582 1.0625418767157067 0.6587522726868424 0.8547578577638111 0.07186599674726732 0.13947834797560182 0.597854326953841 0.03298326952899368 0.028576359315294134 1.542126690943119e-07 6.811879946053315 -0.4037896040288642 KT(ph)SDANETEDHLESLICK ddPTM_PC-9_Lapatinib_30min_R1 1 KTSDANETEDHLESLICK 18 1 F2Z2T1;Q09161 F2Z2T1 NCBP1 Nuclear cap-binding protein subunit 1 1 KT(0.499)S(0.499)DANET(0.001)EDHLESLICK 87.802 0.0013631 41998000.0 39853.0 61904.0 65775.0 53823.0 90567.0 118860.0 122830.0 132670.0 121500.0 104040.0 True False 39284.68891185487 61760.66509137042 60367.23339884242 57781.32296826458 85240.02712157276 113776.63487619295 129189.53638819416 138834.33253564683 107815.39054827933 122023.17537541412 0.3219444895692344 0.5061388125768631 0.494719410580144 0.47352744911362693 0.6985560477288428 0.9324182437159988 1.058729507658952 1.1377701990504003 0.8835648655804654 1.0 16.896795653568347 -6.593875401161773 1.7149277570346864 1.0335066974483191 0.44540326848794415 0.9229221111081047 0.07584110800919143 0.0890445813568181 0.5360375497857632 0.029879558138027545 0.030956638617384888 2.547561041552919e-07 6.593875401161773 -0.588103428960375 down KT(ph)SEDQAAILPGK ddPTM_PC-9_AZD4547_30min_R2 1 KTSEDQAAILPGK 13 1 H3BRS1;Q12968;I3L3K7;H3BR83;Q12968-5;Q12968-6;Q12968-4;Q12968-3;Q12968-2 H3BRS1 NFATC3 Nuclear factor of activated T-cells, cytoplasmic 3 1 KT(0.668)S(0.332)EDQAAILPGK 127.49 9.8841e-05 7701400.0 71301.0 101190.0 85072.0 80267.0 90374.0 101670.0 106310.0 129960.0 127780.0 90039.0 True False 93973.23484706864 133897.68862169897 83943.88969494261 61762.683262787876 77827.13006879213 95312.55882770386 115771.38405024075 109877.66818370495 134534.18993195993 86886.76201573857 1.08155986788927 1.5410597139923903 0.9661297963864405 0.7108411204413424 0.8957305838453804 1.0969744598197715 1.3324398488836546 1.26460769897032 1.5483853559601009 1.0 16.40684876569066 -7.183477837231695 4.523023893498937 1.308632325760265 1.0411421720131584 0.19937798384347838 0.2331549588695503 0.3814478083554969 14.446254917091883 0.09985863743967842 0.07563929526772839 6.554237323410656e-08 7.183477837231695 -0.2674901537471066 KT(ph)SLDVSNSAEPGFLAPGAR ddPTM_PC-9_AZD4547_30min_R2 3 KTSLDVSNSAEPGFLAPGAR 20 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 KT(0.5)S(0.5)LDVSNSAEPGFLAPGAR;KT(0.5)S(0.5)LDVSNSAEPGFLAPGAR;KT(0.896)S(0.104)LDVSNSAEPGFLAPGAR 142.22 2.5762e-05 95534000.0 169338.0 136345.0 149159.0 227696.0 197198.0 160500.0 146431.0 189722.0 138951.0 147938.0 True False 223183.96155079035 180415.8548782049 147181.05420124077 175204.2050681321 169820.46158525322 150463.90962768224 159463.07532556515 160404.82427784646 146295.6661859113 142758.73564882288 1.563364655314742 1.2637815406408197 1.030977568779374 1.227274844315818 1.1895626618815145 1.0539733974515828 1.1170109808049424 1.123607767670567 1.024775580429551 1.0 17.123219503679096 -4.836313665855273 2.636601548252748 1.1077037913270407 1.626539345789679 0.802902881740322 0.07072945832825861 0.17474160442323097 1.7662981889447 0.018269118344280827 0.1929018358853442 1.4577610232678189e-05 4.836313665855273 0.5188355544626384 KT(ph)SLDVSNSAEPGFLAPGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KTSLDVSNSAEPGFLAPGAR 20 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 KT(0.5)S(0.5)LDVSNSAEPGFLAPGAR;KT(0.499)S(0.499)LDVS(0.002)NSAEPGFLAPGAR 74.873 0.0020655 27202000.0 107086.0 98154.0 98829.0 104453.0 112284.0 97270.0 85421.0 107175.0 79107.0 61336.0 True False 125213.54475509125 107898.08044281235 101185.45817106942 98600.83705119521 90282.75623743847 92168.98996595145 77329.30448551566 104361.7698112991 80263.79021925949 72455.73126449127 1.7281385829647302 1.4891586705397104 1.3965142081266642 1.3608424803727983 1.2460402325921147 1.272073145318197 1.0672627704664794 1.4403521707667062 1.107763165432225 1.0 16.14481219134452 -1.5228787452803376 0.2987190823532111 1.1285360179725183 5.996297691997672 0.7378581822355776 0.1068399610038906 28.336685740283762 0.40364949307423037 0.10647891044254693 73.5996273918229 0.029999999999999995 1.5228787452803376 4.867761674025154 KT(ph)SLDVSNSAEPGFLAPGAR ddPTM_PC-9_Lapatinib_30min_R1 2 KTSLDVSNSAEPGFLAPGAR 20 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 KT(0.5)S(0.5)LDVSNSAEPGFLAPGAR;KT(0.486)S(0.486)LDVS(0.027)NS(0.001)AEPGFLAPGAR 108.47 8.400299999999999e-05 36564000.0 114949.0 90010.0 90329.0 92024.0 83303.0 76880.0 63272.0 52001.0 77417.0 72786.0 True False 113309.80618093497 89801.58737519791 82902.4983000235 98791.75194306472 78403.28131999941 73592.02161603318 66547.91456772633 54417.1562989837 68697.48222284896 85366.96311875124 1.3273261931938862 1.0519477804344264 0.9711309301784636 1.1572597681100438 0.9184265019587862 0.8620667636221483 0.7795511534731963 0.6374498320068589 0.8047314758905749 1.0 16.38139023667692 -6.509303762530273 1.296958799450895 0.7749097754957147 1.1288731519224524 0.5885839506722099 0.12089213070312349 0.2990121696019505 1.0431250148908975 0.05209815824472601 0.05913693411734338 3.095253600605503e-07 6.509303762530273 0.3539633764267377 KT(ph)SPASLDFPESQK ddPTM_PC-9_AZD4547_30min_R2 1 KTSPASLDFPESQK 14 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 KT(0.899)S(0.096)PAS(0.005)LDFPESQK 81.643 0.0086411 112670000.0 120700.0 101600.0 131190.0 163640.0 150190.0 131000.0 125350.0 132440.0 119620.0 122420.0 True False 159080.0892840379 134440.2131037121 129450.33488197683 125915.32621279744 129338.71096810942 122808.54929112994 136505.9071648738 111974.44116843579 125942.86899092987 118134.11306174785 1.3466058631251405 1.1380304098397147 1.0957913131689072 1.0658676223944088 1.0948464217148268 1.0395688942696746 1.15551641796746 0.9478586520551228 1.0661007707832915 1.0 16.85006609995569 -1.5228794238684051 0.8627629119984225 1.0520512062316227 114.23461084090006 0.7435325164968727 0.05170808635088258 350.58134450938456 0.9193476711285593 0.017064959611857982 77949.59439771369 0.02999995312483356 1.5228794238684051 113.18255963466844 KT(ph)SPASLDFPESQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KTSPASLDFPESQK 14 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 KT(0.497)S(0.497)PAS(0.007)LDFPESQK 69.975 0.024166 62877000.0 72550.0 60559.0 57791.0 75819.0 88691.0 76671.0 92356.0 89872.0 71327.0 70054.0 True False 84831.28207218365 66570.89729951185 59168.95661358795 71571.10723851447 71312.6352236708 72650.23778841832 83607.3710804634 87512.9552272553 72370.02243757328 82754.23565284116 1.0250989741244885 0.8044409663667325 0.7149961104324034 0.8648633713295284 0.8617400023224365 0.8779035564196411 1.0103092659957758 1.0575042417692944 0.8745174415140482 1.0 16.336545535565513 -7.141293479994582 3.78657593482425 0.990175653104114 0.8460473678869195 0.3559262950757922 0.08378190749476114 0.26264210251013853 6.674343522800406 0.03441543068651173 0.02610883903720149 7.222815477477928e-08 7.141293479994582 -0.14412828521719456 KT(ph)SPASLDFPESQK ddPTM_PC-9_Lapatinib_30min_R1 2 KTSPASLDFPESQK 14 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 KT(0.911)S(0.088)PAS(0.001)LDFPESQK;KT(0.69)S(0.199)PAS(0.111)LDFPESQK 106.6 0.0025640999999999997 81138000.0 178080.0 138450.0 160867.0 145747.0 174732.0 168102.0 151808.0 140352.0 165070.0 139593.0 True False 175540.54654412786 138129.42753134266 147641.1362245777 156465.72057773898 164454.60729632957 160912.66932490125 159667.87543775127 146873.26630016672 146478.07833583932 163721.46405401925 1.072190183238338 0.8436855138662052 0.9017824087858394 0.9556823931534947 1.0044779909985928 0.9828440654049413 0.9752409457141764 0.8970923094830527 0.8946785272303054 1.0 17.32088394746671 -4.728510574283966 24.50172236107853 0.9401116528946547 1.0721913954377325 0.3812343906625416 0.05070915457680959 4536.161088770559 3375023.6883824104 0.013511120293937482 2.241554173338845 1.868484182496671e-05 4.728510574283966 0.13207974254307775 KT(ph)SQSEEEEAPR ddPTM_PC-9_AZD4547_30min_R2 1 KTSQSEEEEAPR 12 1 Q7RTP6;A0A5F9ZHV5;J3KSK6;Q7RTP6-2;Q7RTP6-4;Q7RTP6-3;Q7RTP6-5 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 KT(0.976)S(0.023)QSEEEEAPR 64.22399999999999 0.037784 4975800.0 9871.7 11322.0 12376.0 15146.0 12624.0 14278.0 12501.0 15976.0 15015.0 14550.0 True False 13010.695255884319 14981.615086222728 12211.88615366525 11654.323703367329 10871.375506101667 13385.194402891244 13613.564782354095 13507.27629195809 15808.662246269967 14040.608928675321 0.926647506669914 1.0670203238568647 0.8697547389646864 0.8300440360222233 0.7742809134081723 0.9533200782734205 0.9695850693876198 0.9620149924104787 1.1259242620157113 1.0 13.777317884944773 -7.7351775620933365 1.5818376545267494 1.0531905954652452 0.9014482602710443 0.35115183740541767 0.08050578952819551 0.4950722843579457 2.346568449484053 0.06770696778648498 0.027100993133650917 1.840019552299611e-08 7.7351775620933365 -0.15174233519420088 KT(ph)SVTT(ph)PS(ph)S(ph)SKSAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KTSVTTPSSSKSAGR 15 2 A0A0B4J2F5 A0A0B4J2F5 DUSP10 4 KT(0.391)S(0.391)VT(0.391)T(0.81)PS(0.944)S(0.779)S(0.143)KS(0.15)AGR 45.864 0.033039 1518900.0 3355.9 2479.3 2029.1 2888.4 3114.5 4052.4 2225.1 3145.1 3536.7 2310.1 True False 3923.9875879537017 2725.428518877123 2077.4814394046025 2726.572312319147 2504.2360826253203 3839.885010157516 2014.3224196710503 3062.544457508904 3588.4175467209548 2728.9028432584605 1.4379359813588102 0.9987268420383963 0.761288165511959 0.9991459824430646 0.9176713963312538 1.4071167904140116 0.7381436919409847 1.1222621813285434 1.314967132518425 1.0 11.414105316121205 KT(ph)TLY(ph)DMDVEPS(ph)WK ddPTM_PC-9_Lapatinib_30min_R1 1 KTTLYDMDVEPSWK 14 1 O60336-4;O60336-3;O60336-6;O60336;O60336-2 O60336-4 MAPKBP1 Mitogen-activated protein kinase-binding protein 1 3 KT(0.789)T(0.342)LY(0.869)DMDVEPS(1)WK 42.633 0.046194 0.0 12021.0 9851.1 9180.0 8446.8 6620.3 8173.9 8519.9 8771.5 10447.0 8633.0 True False 11849.578335618591 9828.290383199781 8425.255835824764 9068.005849698773 6230.906970010587 7824.321351291542 8961.018733809131 9179.055911935067 9270.34884821296 10125.202547250576 1.1703053129377898 0.9706759284404223 0.8321073871369201 0.8955876000881704 0.6153859086702956 0.7727570203932541 0.8850211827359868 0.9065552880645902 0.9155716939934455 1.0 13.305663147891519 -4.823484613409561 1.9485988280492748 0.8396945158447433 1.2536394459921614 0.49341854907488425 0.0981756840288863 0.5972186899737205 2.6414655568917436 0.027946511979103972 0.43858607512614706 1.501465600137138e-05 4.823484613409561 0.41394493014741807 KTAEISSTALRS(ph)S(ph)PIMRK ddPTM_PC-9_AZD4547_30min_R2 1 KTAEISSTALRSSPIMRK 18 3 A0A087WWN8;A0A087WZV0;O43314-2;O43314;K7ENU7;H0Y9S9 A0A087WWN8 PPIP5K2 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 2 KT(0.001)AEIS(0.009)S(0.009)T(0.009)ALRS(0.986)S(0.986)PIMRK 51.591 0.04326 0.0 28463.0 26541.0 37567.0 54543.0 45960.0 37428.0 27532.0 36558.0 26284.0 33611.0 True False 37513.64193282166 35119.85921245691 37068.83703415825 41968.954030949695 39579.247327347315 35087.62124327031 29982.29466344875 30908.80111926664 27673.31858015051 32434.289120392204 1.1566044131127864 1.0828003376949682 1.142890380503274 1.2939686723259436 1.2202902668972913 1.081806390546414 0.9244011654504914 0.95296681251551 0.8532118116549575 1.0 14.98523219839581 -7.098690290872697 3.0792774016547146 0.9277511412871211 1.1775530515987311 0.7788694337246023 0.061788614048879684 0.13148283088846957 2.388158545565888 0.02774145015933127 0.02114181763757151 7.967273193186358e-08 7.098690290872697 0.24980191031161003 KTAPTLS(ph)PEHWK ddPTM_PC-9_AZD4547_30min_R2 1 KTAPTLSPEHWK 12 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 KTAPT(0.012)LS(0.988)PEHWK 69.331 0.014852 33669000.0 78073.0 67554.0 75413.0 91172.0 94795.0 78083.0 79077.0 83060.0 70429.0 88884.0 True False 102898.58998071814 89389.50940952913 74412.97434602109 70153.70399335834 81634.3505308069 73200.45766640679 86114.69980755272 70224.9855289208 74151.73315634685 85772.19821418381 1.1996729957155536 1.0421734696167217 0.8675652005583752 0.817907264288317 0.9517577050661079 0.8534287238810899 1.003993153964804 0.8187383207034092 0.8645194445312079 1.0 16.388222474846856 -4.964725543957118 2.6461626247071175 0.892451055770978 1.2098896884857662 0.6836595495796713 0.06503768493927546 0.17905271045613558 2.1699581007141324 0.016581923397487215 0.10601024082864505 1.0846121272222539e-05 4.964725543957118 0.3174386327147881 KTCS(ph)T(ph)S(ph)S(ph)AK ddPTM_PC-9_Lapatinib_30min_R1 1 KTCSTSSAK 9 1 H0YBF7;A0A0A0MRE5;Q9ULH1;Q9ULH1-2 H0YBF7 ASAP1 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 4 KT(0.171)CS(0.844)T(0.999)S(0.994)S(0.992)AK 53.013000000000005 0.046158 0.0 9024.9 6679.1 8184.3 5576.3 7970.7 7591.5 5271.3 7198.9 4772.1 4223.1 True False 8896.203271036033 6663.63495431268 7511.418446311607 5986.399703991487 7501.879096999134 7266.829241650839 5544.222121331015 7533.387174876516 4234.615845559209 4953.057208072965 1.796103476563152 1.3453579626440921 1.5165216412337779 1.2086272079059133 1.5145956894606134 1.4671401795655958 1.1193535403335364 1.520957028842284 0.8549499163177903 1.0 12.274103568934743 -1.5228787452803387 0.08738536852432731 0.6716671037954867 3.2697597825075846 0.47544772448547723 0.19636818481125712 151.47310708332085 0.9589976668227219 3.8733068144130556 47.225665200497396 0.02999999999999992 1.5228787452803387 2.598092678712098 KTDVISDT(ph)FPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KTDVISDTFPGK 12 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 KTDVIS(0.003)DT(0.997)FPGK 74.141 0.017963 6011400.0 45249.0 44946.0 54617.0 75351.0 64926.0 63650.0 58141.0 64436.0 56233.0 51617.0 True False 52908.76199151257 49407.94184223416 55919.27641612597 71129.3277612382 52204.21637519075 60312.08195057885 52633.4635756121 62744.62327558539 57055.30124261586 60974.753500052786 0.8677158816470946 0.8103016249535374 0.9170890115378254 1.1665373565007788 0.856161171281251 0.9891320339741372 0.8632009242245897 1.0290262719230356 0.9357200803208899 1.0 15.895924400263073 -5.519006482241693 24.99253882125464 0.9746338498280651 0.8451803655587943 0.30126154079032075 0.08386349642857399 184.780468883196 1192616.6612099828 0.02203466532393868 0.039307775410560436 3.0268682489917136e-06 5.519006482241693 -0.12945348426927084 KTDVISDT(ph)FPGK ddPTM_PC-9_Lapatinib_30min_R1 2 KTDVISDTFPGK 12 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 KTDVIS(0.001)DT(0.998)FPGK;KTDVIS(0.003)DT(0.997)FPGK 78.22800000000001 0.031101999999999998 5840500.0 210300.0 132184.0 177420.0 156983.0 130938.0 124132.0 99604.0 106491.0 130181.0 91977.0 True False 207301.08343570336 131877.9360693608 162833.21246100552 168528.05349993674 123236.48427401269 118823.16372582503 104761.00775388507 111438.96062450862 115518.64491329675 107875.10189835115 1.9216768261413983 1.2225057844545733 1.50946056685481 1.5622516274305616 1.1423997021123216 1.1014883104146687 0.9711324106335452 1.0330368978887792 1.0708554882492531 1.0 16.719002396605134 -6.368849384320093 3.053432291187732 1.0369163274139184 1.5304432622408493 0.6971936768952633 0.16227819514437314 0.15530169446114522 2.7747646672707 0.05173296361014271 0.06013461425968557 4.2771119299292743e-07 6.368849384320093 0.4935269348269309 KTEFLDLDNSPLSPPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 KTEFLDLDNSPLSPPSPR 18 1 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 KTEFLDLDNS(0.025)PLS(0.043)PPS(0.932)PR 98.06700000000001 0.00033644 3483500.0 23938.0 26085.0 33238.0 39646.0 38239.0 41386.0 25123.0 36113.0 25225.0 30161.0 True False 31549.786058668615 34516.46613002295 32797.24240267662 30506.227224594044 32930.17490318612 38798.12687757787 27358.898330300115 30532.565644183942 26558.342002141835 29105.072570293927 1.0839961309998547 1.1859261318335332 1.1268565753775546 1.0481412527289213 1.131423906387929 1.3330365964171194 0.9400044704998934 1.0490461953132866 0.9124987384243319 1.0 14.828982994341004 -7.309509457416737 24.999990726912273 0.9794744679147803 1.1463861524313554 0.5455723876171719 0.07864913249257761 334.12989201208234 173770.89715972936 0.03302735972217929 0.022267074042742682 4.903323449499906e-08 7.309509457416737 0.16691168451657512 KTESHHK ddPTM_PC-9_AZD4547_30min_R2 2 KTESHHK 7 1 A0A0U1RR32;A0A0U1RRH7;Q99878;Q96KK5;Q93077;Q7L7L0;Q6FI13;P20671;P0C0S8;P04908 A0A0U1RR32 HIST1H2AJ;HIST1H2AH;HIST1H2AC;HIST3H2A;HIST2H2AA3;HIST1H2AD;HIST1H2AG;HIST1H2AB Histone H2A type 1-J;Histone H2A type 1-H;Histone H2A type 1-C;Histone H2A type 3;Histone H2A type 2-A;Histone H2A type 1-D;Histone H2A type 1;Histone H2A type 1-B/E 0 ; 66.07300000000001 0.021902 3057000.0 11681.2 422.42 44080.0 31131.0 62196.0 67692.0 12402.2 42828.0 18174.9 67916.0 False True 15395.578615946188 558.9590041266737 43495.47039863964 23954.22891915543 53561.15898110735 63459.2085390471 13505.971773755055 36209.916689533144 19135.588109206252 65538.28151202164 0.23490970865817085 0.008528740626562573 0.6636651037403429 0.36549980204716725 0.8172499758218815 0.9682769684372456 0.20607760017750335 0.5525002464840519 0.2919757379615794 1.0 16.00005022382792 -5.264347482174704 24.96131615875272 0.589476468466344 0.1217192070070449 0.35524546327148676 0.26116326319052746 256.85639268500626 2204713.8385820757 0.0677534900755322 0.15166903152918915 5.440671665494316e-06 5.264347482174704 -0.46775726145929913 KTETQEKNPLPS(ph)KETIEQEK ddPTM_PC-9_Lapatinib_30min_R1 1 KTETQEKNPLPSKETIEQEK 20 3 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 1 KT(0.033)ET(0.033)QEKNPLPS(0.7)KET(0.234)IEQEK 49.425 0.046406 12543000.0 26743.0 21140.0 22283.0 23294.0 23132.0 18494.0 14441.0 16778.0 29200.0 32785.0 True False 26361.639915934436 21091.051628837737 20450.977754867454 25007.118466506046 21771.421239261806 17703.054731619653 15188.684319644319 17557.56713110034 25911.18851036836 38451.84356673346 0.6855754489426135 0.5485056026568417 0.531859485992515 0.6503490118258181 0.5661996726236894 0.46039547364994005 0.39500536023153854 0.4566118423068337 0.6738607595081701 1.0 15.230765149149383 -8.60793444778716 4.311823197533849 0.9999087609611059 0.5354009808929225 0.7417510513022645 0.08283883465944569 0.2409968340250478 10.783402023539281 0.08786461006021651 0.02295035352879733 2.4664115881904798e-09 8.60793444778716 -0.4645077800681834 KTEVQAHS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 1 KTEVQAHSPSR 11 1 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 KTEVQAHS(0.959)PS(0.041)R 72.523 0.009910299999999999 2827700.0 22655.0 18895.0 22320.0 21381.0 21730.0 22477.0 15162.0 20383.0 23870.0 14595.0 True False 22331.93554558182 18851.249788405345 20484.935757691583 22953.430064925124 20451.884122823758 21515.711106446142 15947.01417176424 21330.068591799863 21181.50923775661 17117.726303384934 1.3046087517572824 1.1012706626041577 1.1967089200182388 1.3409158236386927 1.1947780774354075 1.256925757843875 0.9316081989586904 1.2460807126926643 1.2374020277195392 1.0 14.063203465127623 KTGQIWPNDGEGAFHGDADGS(ph)FGTPPGYGCAADR ddPTM_PC-9_Lapatinib_30min_R1 1 KTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADR 34 1 P11274-2;P11274 P11274-2 BCR Breakpoint cluster region protein 1 KTGQIWPNDGEGAFHGDADGS(0.498)FGT(0.498)PPGY(0.004)GCAADR 46.06 0.0042153 4963400.0 8643.7 9149.2 10795.0 9075.9 11467.0 10168.0 9056.2 9409.7 14978.0 10884.0 True False 8520.439252939555 9128.015589525176 9907.476769905046 9743.371962314852 10792.533604989403 9733.138342765684 9525.085723673079 9846.909013798717 13291.019914667726 12765.284897981614 0.6674695724407034 0.7150655596388964 0.7761265689786186 0.7632710151150193 0.845459673735591 0.7624693393489903 0.7461710255428095 0.7713818447840254 1.041184746042702 1.0 13.639938115987672 -8.25046702664528 10.33442427585216 1.020718854786596 0.7583074668343439 0.8534202317011494 0.043865818827902414 0.11219286632909796 105.21498767362559 0.03429939211055693 0.011947144661456986 5.6173692602574716e-09 8.25046702664528 -0.26241138795225205 KTGS(ph)PGSPGAGGVQSTAK ddPTM_PC-9_AZD4547_30min_R2 1 KTGSPGSPGAGGVQSTAK 18 1 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 KT(0.002)GS(0.522)PGS(0.476)PGAGGVQSTAK 104.66 0.00016537 19498000.0 39826.0 40074.0 46674.0 69443.0 56600.0 48376.0 38735.0 59458.0 46976.0 47056.0 True False 52489.83956773898 53027.13681021811 46055.07226375018 53433.989233654924 48742.06698711619 45351.04107257791 42182.339960362 50270.132308916145 49459.05545659528 45408.5837627317 1.1559453129392485 1.167777816795493 1.0142371430123542 1.1767376298908034 1.073410860858435 0.9987327794574157 0.9289507944306867 1.1070623248588183 1.0892005730684764 1.0 15.47067742114883 -6.521504262559381 6.307867853099691 1.0262638157725594 1.123735918895748 0.37847708438840477 0.06260588569827906 0.1775490597982985 32.20080297146198 0.021216096080764916 0.022316154434516434 3.0095096306750525e-07 6.521504262559381 0.09747210312318866 KTGS(ph)PGSPGAGGVQSTAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KTGSPGSPGAGGVQSTAK 18 1 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 KT(0.171)GS(0.415)PGS(0.415)PGAGGVQSTAK;KT(0.183)GS(0.445)PGS(0.372)PGAGGVQSTAK;KT(0.187)GS(0.488)PGS(0.325)PGAGGVQSTAK 77.689 0.002209 15531500.0 116428.0 89847.0 86065.0 128811.0 144302.0 137942.0 133049.0 160061.0 127865.0 114028.0 True False 136136.96084218076 98766.41638186321 88117.11600333011 121594.13728089641 116027.05898057432 130708.07868698746 120445.63552865644 155859.568348648 129734.78372818617 134700.37375484838 1.010665056430704 0.733230455333523 0.6541712806506481 0.9027008158284325 0.8613714702213146 0.970361663026067 0.8941744716155335 1.1570834141285227 0.9631360337893385 1.0 17.039394328306948 -6.8499023976042475 1.1130736475211587 1.0300008047694376 0.8030806801891606 0.38427897777461273 0.10669757820093433 0.4793447404410922 1.2513947719034708 0.05976000089127474 0.049500611523551286 1.4128550309075718e-07 6.8499023976042475 -0.226920124580277 KTGS(ph)PGSPGAGGVQSTAK ddPTM_PC-9_Lapatinib_30min_R1 1 KTGSPGSPGAGGVQSTAK 18 1 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 KT(0.097)GS(0.569)PGS(0.334)PGAGGVQSTAK 115.83 5.8108e-05 6752400.0 65445.0 61264.0 63012.0 50335.0 63538.0 62916.0 62611.0 54478.0 65721.0 59409.0 True False 64511.74229885688 61122.146972048955 57831.39659335401 54036.803812637714 59800.81976051431 60225.22934435937 65852.69122202408 57009.24676171677 58318.80890718908 69677.76649248345 0.9258583554887072 0.8772116278819378 0.8299835012592234 0.7755243391515281 0.8582482299711109 0.8643392630970199 0.9451033598949816 0.818184187460525 0.8369787357274184 1.0 16.088410758913007 -7.009871014486159 22.445798516423995 0.8877446810058006 0.8502892254683397 0.10672480390411909 0.05983985605689393 360.4790322173571 819698.7505388792 0.022438818327355715 0.018647291067450673 9.775275036339148e-08 7.009871014486159 -0.03745545553746088 KTGS(ph)YGALAEITASK ddPTM_PC-9_AZD4547_30min_R2 3 KTGSYGALAEITASK 15 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 KT(0.031)GS(0.966)Y(0.003)GALAEITASK;KT(0.176)GS(0.817)Y(0.007)GALAEIT(0.001)ASK;KT(0.349)GS(0.65)Y(0.001)GALAEITASK 107.09 0.00040125 120072200.0 186062.0 201843.0 318123.0 412178.0 363385.0 350533.0 264793.0 382850.0 300535.0 352635.0 True False 245225.8456699801 267084.8024950053 313904.481162124 317156.7301866192 312935.26523168274 328614.1160967004 288359.06402798806 323689.32951778657 316420.66654563736 340289.3559837398 0.7206391894364684 0.7848755707415296 0.9224634142747723 0.9320207188666051 0.9196152031468063 0.9656902583588385 0.8473937223054572 0.9512179086002724 0.9298576666640054 1.0 18.376402499940042 -5.146160461967254 2.581863054117941 0.9308288320835014 0.7235948063235526 0.7980489945799805 0.03702141844804971 0.12489984732128061 1.5277850621121043 0.009543711130873487 0.03869516345781505 7.1423238464114265e-06 5.146160461967254 -0.20723402575994887 KTGS(ph)YGALAEITASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KTGSYGALAEITASK 15 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 KT(0.08)GS(0.919)Y(0.002)GALAEITASK;KT(0.022)GS(0.978)YGALAEITASK 95.227 0.00132 146583300.0 243024.0 218238.0 307653.0 386782.0 415062.0 370107.0 362939.0 314435.0 328901.0 280029.0 True False 284163.16325720627 239903.22635530465 314988.6143004995 365111.8585041624 333733.5806474968 350697.9373838629 328558.79046918766 306181.4144214219 333710.5549054396 330796.04099165497 0.8590283076101715 0.7252300409525055 0.9522139786081834 1.1037370864827645 1.0088802140649438 1.0601636474624858 0.9932367675388117 0.925589718376182 1.0088106069983411 1.0 18.335582442694836 -5.422670815005159 5.00266529576168 1.0131820637990454 0.795240253467772 0.7320860767669557 0.05293506631784758 0.1078493936709544 4.184809542847359 0.014291147416312159 0.030522046372408383 3.7785849024919485e-06 5.422670815005159 -0.21794181033127336 KTGS(ph)YGALAEITASK ddPTM_PC-9_Lapatinib_30min_R1 2 KTGSYGALAEITASK 15 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 KT(0.005)GS(0.995)YGALAEITASK;KT(0.04)GS(0.96)YGALAEITASK 116.87 0.00020202 97440000.0 320950.0 209300.0 314780.0 232860.0 217950.0 232450.0 199355.0 197340.0 247890.0 164648.0 True False 316373.19414497836 208815.37870935365 288900.0034859392 249985.30119818833 205130.6095061867 222508.6553674158 209676.62644849345 206509.13682508888 219970.01780257578 193107.18742033033 1.6383294602926342 1.081344415497243 1.4960603349118209 1.2945416715849793 1.0622629444635086 1.1522546536970073 1.0858043620722255 1.0694016084216842 1.1391083922928977 1.0 17.559042336616073 -1.522878750401413 0.2580512505925526 1.018909332168253 4.226031433357495 0.5488709970495446 0.13396583532605483 40.634409146952045 0.5592242137131525 0.16210213930665976 57.163341690970206 0.029999999646248644 1.522878750401413 3.207122101189242 KTGSPGS(ph)PGAGGVQSTAK ddPTM_PC-9_AZD4547_30min_R2 1 KTGSPGSPGAGGVQSTAK 18 1 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 KT(0.125)GS(0.125)PGS(0.751)PGAGGVQSTAK 84.602 0.00088429 8525300.0 39664.0 20681.0 36293.0 48350.0 41650.0 39857.0 31071.0 45874.0 31933.0 34864.0 True False 52276.32693754834 27365.728811002667 35811.73110657508 37203.654500053526 35867.61643133194 37364.735489286766 33836.25880749731 38785.22737964982 33620.91318748843 33643.421971775715 1.5538350106420276 0.8134050345401975 1.0644497202638425 1.1058225447834817 1.0661108272940296 1.1106104343557248 1.0057317842365552 1.1528324143776958 0.9993309603194893 1.0 15.038036833377673 -4.744287202680802 24.9902855582717 1.0456387300985763 1.5538365366457962 0.7510919280920627 0.08936403804659127 523.9617497349013 763358.267184746 0.021654636097806025 0.6299471795838614 1.8018257838700338e-05 4.744287202680802 0.5081978065472199 KTGSYGALAEIT(ph)ASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KTGSYGALAEITASK 15 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 KT(0.006)GS(0.101)YGALAEIT(0.812)AS(0.081)K 105.19 0.0036573 46316000.0 79621.0 83144.0 127850.0 138870.0 154750.0 136670.0 137270.0 137590.0 141380.0 113130.0 True False 93099.26271356764 91397.98684044684 130898.42887382531 131089.5641226146 124427.8483821699 129502.78460621556 124266.79185126313 133978.40828865566 143447.41503531777 133639.57346341285 0.6966444167756632 0.6839140867616531 0.9794885263507819 0.980918755764389 0.9310703795102663 0.969045180630348 0.9298652235318923 1.0025354377933238 1.0733902489937988 1.0 17.02798775758898 -5.262149713765353 24.94647065018808 0.9790134434896131 0.6902792261739421 0.9026510398311369 0.038469520502549814 16.44629390632962 577608.7618437656 0.010515486107589343 0.024191754594922007 5.46827423300153e-06 5.262149713765353 -0.28873421731567095 KTIMQVS(ph)S(ph)GS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KTIMQVSSGSR 11 1 K7EJ87 K7EJ87 POLR2E 3 KT(0.029)IMQVS(0.992)S(0.981)GS(0.998)R 52.821000000000005 0.037676999999999995 0.0 9339.7 9010.6 9733.0 11469.0 13259.0 14848.0 13706.0 14869.0 14909.0 10432.0 True False 10920.726742516514 9905.112819019167 9965.07163260805 10826.42911299969 10660.994130527892 14069.34474158987 12407.668457153113 14478.704505007754 15127.015919943093 12323.239020333434 0.8861896393064547 0.8037751116143782 0.8086406192532344 0.8785376227090947 0.8651129879845042 1.1416921085743243 1.0068512374612202 1.1749106287006026 1.2275194772237563 1.0 13.589093881069875 -6.736391232418604 7.035146893221481 1.1148915451597274 0.8443536262209143 0.780645367235552 0.06934632588759726 0.0792063227848767 14.388728797244124 0.02361477081707243 0.02303728261440481 1.8348846502205192e-07 6.736391232418604 -0.2705379189388132 KTKPPRPDS(ph)PATTPNISVK ddPTM_PC-9_Lapatinib_30min_R1 1 KTKPPRPDSPATTPNISVK 19 3 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 KTKPPRPDS(0.931)PAT(0.055)T(0.014)PNISVK 79.416 0.0023069 9318400.0 72210.0 50316.0 66898.0 41663.0 52635.0 47751.0 34611.0 45748.0 58744.0 38293.0 True False 71180.27215830793 50199.49639340581 61397.90467374776 44727.03600369372 49539.112784391524 45708.80104301771 36402.98822707636 47873.61909128494 52127.632118256166 44911.894027784794 1.5848868924181236 1.1177327850468706 1.367074491130654 0.9958839851203622 1.1030288046579397 1.017743785526834 0.8105422631375914 1.0659452273749104 1.1606643016659985 1.0 15.454809944394032 -1.5228787969963598 0.5544691612944319 1.0081904677087106 25.383431657236326 0.6187644103306342 0.12623711910874205 92.2162413947068 0.8326839250774029 0.0618023595545521 2681.585870640661 0.02999999642758396 1.5228787969963598 24.375241189527614 KTLEEEAK ddPTM_PC-9_Lapatinib_30min_R1 2 KTLEEEAK 8 1 P35579 P35579 MYH9 Myosin-9 0 ; 97.965 0.0035759 6541300.0 52492.0 41118.0 34868.0 38490.0 39858.0 32629.0 34665.0 34539.0 43775.0 36189.0 False True 51743.454454146166 41022.79379728237 32001.287634372304 41320.68299887602 37513.63080384303 31233.53373191398 36459.78408285233 36143.80803081861 38844.59852881425 42444.22043118858 1.2190930573936136 0.9665107140744721 0.7539610177610266 0.9735290830907342 0.883833662692919 0.7358724795652781 0.8590046822031203 0.8515601809536277 0.9151917065313966 1.0 15.373280496980666 -4.82553340233071 3.2810399779234207 0.8645944015556069 1.2507931786150233 0.6335378266548162 0.07937413199722598 0.1739401635694884 3.0307401049576224 0.019573832925038795 0.16168336924174725 1.4943991011579064e-05 4.82553340233071 0.3861987770594164 KTPESFLGPNAALVDLDSLVSRPGPT(ph)PPGAK ddPTM_PC-9_AZD4547_30min_R2 1 KTPESFLGPNAALVDLDSLVSRPGPTPPGAK 31 2 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 KTPESFLGPNAALVDLDS(0.012)LVS(0.048)RPGPT(0.94)PPGAK 78.645 4.5141999999999995e-07 864500.0 4017.2 3707.4 4723.2 6688.2 6991.5 5215.1 4648.4 4585.5 5432.5 5312.9 True False 5294.586037049189 4905.744547841556 4660.567281915945 5146.338821659938 6020.850907074608 4888.998972581463 5062.098594855988 3876.9163393073263 5719.650859331444 5126.8969881209 1.0327077078624416 0.9568642707681162 0.9090425051867733 1.0037921248630672 1.174365492621563 0.9535980504210149 0.9873610892875261 0.7561915810460406 1.1156164971880582 1.0 12.32387019542243 KTPLALAGS(ph)PTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KTPLALAGSPTPK 13 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 KTPLALAGS(0.831)PT(0.168)PK 111.09 0.0002768 30392000.0 64237.0 66527.0 70014.0 82746.0 84363.0 75537.0 106290.0 86330.0 84622.0 74261.0 True False 75111.05536141775 73131.36089837401 71683.39928957372 78110.00988615146 67832.6757548626 71575.70674471126 96221.44172703965 84063.92897419611 85859.43666090436 87723.93145024746 0.8562208067933766 0.8336534818876693 0.8171475913642663 0.8904070827064046 0.7732516615871672 0.8159199611944588 1.0968665008089789 0.9582781754585735 0.9787458820128172 1.0 16.42068284906982 -7.2449188404202305 24.98896032124657 1.0049958209210905 0.8306482433513747 0.796619688436474 0.043891285125799 351.04247732042955 530987.3274026648 0.01664221826270869 0.01285422260164993 5.689592462147774e-08 7.2449188404202305 -0.17434757756971586 KTPLALAGS(ph)PTPK ddPTM_PC-9_Lapatinib_30min_R1 1 KTPLALAGSPTPK 13 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 KTPLALAGS(0.555)PT(0.445)PK 103.66 0.00090698 36609000.0 227760.0 267180.0 267630.0 252710.0 306410.0 291720.0 297320.0 325650.0 332370.0 284570.0 True False 224512.10063393085 266561.3611254903 245626.4944816752 271295.13641584653 288387.5662252381 279243.81563253375 312713.7748020671 340780.8878437737 294934.9905887374 333757.54533431056 0.6726802248292147 0.7986676701450667 0.7359428960194495 0.8128509458688099 0.8640630609155897 0.8366666747648424 0.936948929465655 1.0210432471344675 0.8836803683144114 1.0 18.348440926947397 -6.372914331416865 0.4560058025935876 0.9942681685285404 0.6777815654521097 0.7978400956081921 0.0469205951410996 0.6124352449241597 0.24540981346909838 0.041736955371021206 0.08850437876417808 4.2372654176592213e-07 6.372914331416865 -0.31648660307643073 KTPLALAGSPT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 KTPLALAGSPTPK 13 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 KTPLALAGS(0.028)PT(0.972)PK;KTPLALAGS(0.079)PT(0.921)PK 118.23 0.00020922 102194000.0 522320.0 490470.0 607470.0 607790.0 671970.0 655710.0 653900.0 656100.0 646530.0 706080.0 True False 688406.8950690862 649004.8358363952 599414.5508861535 467673.40576189244 578678.5645465088 614708.3500434108 712095.8332278482 554714.8206781237 680704.2558828443 681360.3541140265 1.0103418711002379 0.9525133534960318 0.879732064342917 0.6863818872614162 0.849298849063452 0.9021780418127153 1.045108992515109 0.8141284084534386 0.9990370760094557 1.0 19.378058479125116 -7.008336329480635 23.774632031588542 0.9525884904899184 0.8702453951848917 0.1547355033172194 0.09636708137186793 461.1308775269469 1315116.491818669 0.037303411538236714 0.03135043097141861 9.809879449813843e-08 7.008336329480635 -0.0823430953050267 KTPLALAGSPT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KTPLALAGSPTPK 13 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 KTPLALAGS(0.121)PT(0.879)PK;KT(0.003)PLALAGS(0.053)PT(0.944)PK 109.87 0.00062726 33972300.0 129198.0 132600.0 152921.0 167017.0 201396.0 196754.0 221216.0 201833.0 173010.0 155681.0 True False 151068.6696231836 145763.65167712895 156567.2165961222 157659.57896642014 161933.89953328302 186435.87387437833 200260.81901485386 196535.0976097408 175539.9439472371 183904.73292988236 0.8214506892586706 0.7926041345151486 0.8513495770433315 0.8572894044359981 0.8805314412164901 1.0137633268278148 1.088937820274629 1.0686788451750941 0.9545156405200593 1.0 17.488599083531987 -6.684450527363177 2.539720699163546 1.0371395168618491 0.8305181181829349 0.8560642597588211 0.038223475337594105 0.10175061218210077 1.3391429207040613 0.014781931767305165 0.014336902708287334 2.0679949440553427e-07 6.684450527363177 -0.20662139867891427 KTPLALAGSPT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 KTPLALAGSPTPK 13 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 KTPLALAGS(0.33)PT(0.67)PK 124.84 0.00012629 38684000.0 205070.0 229830.0 207610.0 255260.0 298870.0 274610.0 256050.0 259960.0 272220.0 252290.0 True False 202145.66419476786 229297.84275571298 190541.1071977752 274032.671922398 281291.05420102767 262865.5704471759 269307.01613772765 272038.6906306377 241559.71699631787 295897.9903447055 0.6831599767179184 0.7749219333615383 0.6439418766440587 0.9261052148517953 0.950635230314807 0.8883655145509822 0.91013465763657 0.9193664692136875 0.8163614653648494 1.0 18.174740372626054 -5.770222302986718 24.9993224909639 0.9125586745011718 0.7080993254566494 0.7736695047909248 0.053267428775172106 81.78485354605628 232789.1263997311 0.0142865817579603 0.021559487178055666 1.6973745923049407e-06 5.770222302986718 -0.20445934904452234 KTPSKPPAQLS(ph)PSVPK ddPTM_PC-9_AZD4547_30min_R2 1 KTPSKPPAQLSPSVPK 16 2 P18887;F5H8D7;M0QYS5 P18887 XRCC1 DNA repair protein XRCC1 1 KTPS(0.001)KPPAQLS(0.653)PS(0.346)VPK 74.96600000000001 0.035766 14909000.0 46493.0 39642.0 47186.0 82839.0 63180.0 63566.0 46984.0 56277.0 60737.0 57717.0 True False 61276.806885524275 52455.50125843855 46560.2828092153 63741.74839979173 54408.54756618371 59591.207971297474 51165.48497993157 47580.68276680808 63947.433822956926 55696.34539768752 1.1001943924325859 0.941812265847814 0.8359665697410096 1.144451183370431 0.9768782346075211 1.069930307739216 0.9186506693499487 0.8542873401669117 1.1481441621771469 1.0 15.76529504554187 -4.748288360977893 24.63984925868801 0.9834539565170973 1.1001947291328416 0.09622652248111929 0.10257104292165069 1322.4034132042304 2477489.3392785895 0.025032625545896914 0.45443886040142784 1.7853017842451044e-05 4.748288360977893 0.11674077261574423 KTPSKPPAQLSPS(ph)VPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KTPSKPPAQLSPSVPK 16 2 P18887;F5H8D7;M0QYS5 P18887 XRCC1 DNA repair protein XRCC1 1 KTPSKPPAQLS(0.168)PS(0.832)VPK 53.453 0.024030000000000003 40404000.0 290860.0 322250.0 257250.0 377750.0 371420.0 343240.0 384230.0 382950.0 350340.0 331860.0 True False 340096.8532531409 354240.850323944 263383.8156260576 356585.89218202455 298642.91726077866 325239.8901605139 347832.9528156964 372897.96826906427 355463.05972183717 392023.5909976855 0.8675418037664697 0.9036212576452712 0.6718570557342113 0.9096031472864341 0.7617983308115298 0.8296436684659473 0.8872755640304055 0.9512130821516449 0.9067389511360703 1.0 18.58058094916324 -7.501420027193906 2.3217438134102273 0.9487267227814942 0.8213652315288346 0.4141171764981202 0.06864757670866754 0.31491951151420533 3.3668217798878914 0.03712877891569306 0.020133286766714883 3.1519547409241684e-08 7.501420027193906 -0.1273614912526596 KTQMAEVLPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KTQMAEVLPSPR 12 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 KTQMAEVLPS(1)PR 50.675 0.039452 6770100.0 75704.0 66504.0 70402.0 84617.0 83523.0 67709.0 69861.0 56574.0 62726.0 61184.0 True False 88519.1919778439 73106.07761037546 72080.6506810718 79876.18382201529 67157.26772487216 64158.2208451177 63243.260330160076 55088.99244510788 63643.2490840667 72276.17486772237 1.224735428235501 1.0114823832912014 0.9972947629421672 1.1051523405631554 0.9291757324980372 0.8876814657463279 0.8750222385994547 0.7622012723546875 0.8805564101938795 1.0 16.141232534819544 -6.444424776924548 2.402089782347283 0.8644730503115334 1.0752629517376597 0.5862962851572828 0.08010204892347064 0.21088089370088428 2.4009654418844497 0.027662756811901782 0.03120699158966402 3.593976417431829e-07 6.444424776924548 0.2107899014261263 KTQS(ph)FYMSSPGPSEYCPSER ddPTM_PC-9_AZD4547_30min_R2 2 KTQSFYMSSPGPSEYCPSER 20 1 J3KNG6;Q08AE8-3;Q08AE8-5;Q08AE8-2;Q08AE8 J3KNG6 SPIRE1 Protein spire homolog 1 1 KT(0.062)QS(0.49)FY(0.426)MS(0.015)S(0.006)PGPSEYCPSER;KT(0.166)QS(0.794)FY(0.039)MS(0.001)SPGPSEYCPSER 74.627 0.0064555 2434500.0 8390.9 8461.6 11848.4 12374.9 14184.099999999999 12293.7 10274.9 12512.5 10221.8 13305.2 True False 11059.031658437738 11196.646724393404 11691.282474392961 9522.057995299108 12214.88255038789 11524.972995575297 11189.346194881213 10578.980633645822 10762.103479781705 12839.388997787695 0.8613362879139558 0.872054482212717 0.9105793489400034 0.7416285928356728 0.9513601116449224 0.8976262809360415 0.8714858780903987 0.8239473572666616 0.8382099398683287 1.0 13.6482889285178 KTRYDTS(ph)LGLLT(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 KTRYDTSLGLLTK 13 2 A0A087X0B6;O00716-2 A0A087X0B6 E2F3 2 KT(0.016)RY(0.028)DT(0.41)S(0.549)LGLLT(0.996)K 83.85600000000001 0.021534 0.0 23070.0 21374.0 25489.0 29814.0 27714.0 30117.0 21896.0 25990.0 22439.0 30321.0 True False 30405.78011419018 28282.727508649023 25150.999205783246 22940.842921708278 23866.389478461795 28233.779229014985 23844.701581827467 21973.84269078562 23625.079729873567 29259.47101899412 1.0391773690799782 0.9666178684600608 0.8595848909727789 0.7840484507329598 0.8156808256365488 0.9649449646812378 0.8149395990907835 0.750999314940487 0.8074335901198307 1.0 14.836616066825835 -5.127558170349909 2.479722075106051 0.8387746630319488 1.0352164296531108 0.4173874889038677 0.07414334223746966 0.2957749563058424 3.287155875779281 0.020078929400380592 0.08769242545317948 7.454900127823546e-06 5.127558170349909 0.19644176662116197 KTS(ph)ASDVTNIYPGDAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KTSASDVTNIYPGDAGK 17 1 Q15042-4;Q15042;Q15042-3 Q15042-4 RAB3GAP1 Rab3 GTPase-activating protein catalytic subunit 1 KT(0.082)S(0.401)AS(0.401)DVT(0.115)NIYPGDAGK;KT(0.046)S(0.923)AS(0.029)DVT(0.002)NIYPGDAGK 140.96 2.4648e-08 10134000.0 45316.9 54448.3 57442.7 87584.3 145807.0 161804.0 198106.0 176013.0 175160.0 144743.0 True False 52988.15612042643 59853.567387721276 58812.351820652846 82677.23562313191 117237.16503430734 153318.71340033703 179339.96551676426 171392.84525118876 177721.3836298368 170983.76011504253 0.30990168940473967 0.3500541065856206 0.3439645483353641 0.4835385276794967 0.6856625737755854 0.8966858214907663 1.0488713395710765 1.0023925379572363 1.0394050494050489 1.0 17.383499780167284 -6.479603370935894 1.2277578398297182 1.0327660068967757 0.32289603749298573 0.9936459224755121 0.023952495377458232 0.03101546823937422 0.09739038162352487 0.010465878414602323 0.01230703765862775 3.3143367245527706e-07 6.479603370935894 -0.70986996940379 down KTS(ph)ATVGPK ddPTM_PC-9_Lapatinib_30min_R1 1 KTSATVGPK 9 1 P16104 P16104 H2AFX Histone H2AX 1 KT(0.052)S(0.856)AT(0.092)VGPK 64.945 0.024051 16195000.0 176860.0 173800.0 141220.0 138860.0 176350.0 125510.0 179600.0 170240.0 165100.0 138130.0 True False 174337.9439678482 173397.57677823983 129609.43672496463 149072.2276233806 165977.43971743993 120142.22987810016 188898.80921045085 178149.9718916752 146504.6994199252 162005.58645334464 1.076123038621604 1.07031850304851 0.8000306629073581 0.9201672046433493 1.0245167672982631 0.7415931296461771 1.1660018234300278 1.0996532637655672 0.9043188116362673 1.0 17.305684036988538 -7.297333513897986 24.99842513592634 1.0507978600594357 0.9415125886603566 0.15242527922332727 0.11905317245058435 1175.9936076815302 819014.6154902759 0.0505997364054675 0.034115533466424666 5.042738946534574e-08 7.297333513897986 -0.10928527139907906 KTS(ph)DANETEDHLESLICK ddPTM_PC-9_AZD4547_30min_R2 1 KTSDANETEDHLESLICK 18 1 F2Z2T1;Q09161 F2Z2T1 NCBP1 Nuclear cap-binding protein subunit 1 1 KT(0.393)S(0.435)DANET(0.166)EDHLES(0.006)LICK 58.758 0.014081 13091000.0 15916.0 17726.0 24356.0 26200.0 21392.0 26956.0 20350.0 25047.0 25501.0 24542.0 True False 20976.956926634204 23455.58284917717 24033.023526072317 20159.994785964886 18422.0900527984 25270.437058715255 22161.110576826293 21176.56167280134 26848.930798676676 23682.792050003427 0.8857467853597595 0.9904061480442623 1.0147884369093567 0.8512507623002993 0.7778681674822093 1.0670379153505085 0.9357473785200544 0.8941750460878736 1.1336894206556525 1.0 14.531551555078908 -8.253310649818284 24.900268824313606 1.0668447141199 0.9296053557436115 0.3047079257398966 0.08435476462255621 656.2783042761735 2010355.5472649822 0.06056317231560449 0.021983824194687158 5.580708651609007e-09 8.253310649818284 -0.13723935837628853 KTS(ph)DFNTFLAQEGCTK ddPTM_PC-9_Lapatinib_30min_R1 1 KTSDFNTFLAQEGCTK 16 1 E9PHZ2;Q9UHD1-2;Q9UHD1 E9PHZ2 CHORDC1 Cysteine and histidine-rich domain-containing protein 1 1 KT(0.035)S(0.965)DFNTFLAQEGCTK 102.48 0.0048714 0.0 22776.0 20879.0 22423.0 21644.0 26329.0 20714.0 20667.0 18553.0 21488.0 22001.0 True False 22451.21006339315 20830.655958301937 20579.467495283083 23235.771962267412 24780.379984805626 19828.11050669241 21737.036135592352 19415.040111056416 19067.795161328628 25803.84353551025 0.8700723220746811 0.8072695034612032 0.7975349667177457 0.900477168461018 0.960336778926125 0.7684169406548189 0.8423952852480556 0.752408844997769 0.7389517431807501 1.0 14.655298353594349 -10.043357976728592 9.796987131742263 0.9999995131043347 0.8277185340630395 0.3850033357495125 0.06579335083136252 0.0 0.0 0.06789573547232121 0.01646713464008095 9.049863385892525e-11 10.043357976728592 -0.17228097904129513 KTS(ph)FAALLK ddPTM_PC-9_Lapatinib_30min_R1 1 KTSFAALLK 9 1 A6NEL2 A6NEL2 SOWAHB Ankyrin repeat domain-containing protein SOWAHB 1 KT(0.12)S(0.88)FAALLK 53.251999999999995 0.046282 1376600.0 14131.0 11312.0 13567.0 11214.0 13812.0 14224.0 11364.0 12926.0 12249.0 11333.0 True False 13929.489348691975 11285.807759007212 12451.573630134479 12038.714968807371 12999.605315436791 13615.672677763478 11952.372315520954 13526.589148682977 10869.388632311715 13291.893949726724 1.047968739547336 0.8490744661139313 0.9367794896069328 0.905718554055638 0.9780100085514193 1.0243591115954858 0.8992226661398159 1.0176570171146362 0.8177456631404425 1.0 13.698259067098164 -4.719066559891115 24.026501948938826 0.9389827554367768 1.0479708391508802 0.2011036108475116 0.06648244502099862 10243.910064807746 5807888.279829149 0.01571529896149012 6.723605720661313 1.9095605772415512e-05 4.719066559891115 0.1089880837141034 KTS(ph)LDVSNSAEPGFLAPGAR ddPTM_PC-9_AZD4547_30min_R2 3 KTSLDVSNSAEPGFLAPGAR 20 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 KT(0.285)S(0.715)LDVSNSAEPGFLAPGAR;KT(0.097)S(0.903)LDVSNSAEPGFLAPGAR;KT(0.006)S(0.948)LDVS(0.044)NS(0.002)AEPGFLAPGAR 163.6 2.6839e-08 54917900.0 150961.0 121712.0 145890.0 173878.0 188763.0 122477.0 106112.0 162033.0 108363.0 149784.0 True False 198963.45781613654 161053.02379211615 143955.4032771672 133793.11348832064 162556.51573655527 114818.493828471 115555.76243381813 136994.52299792456 114090.84695255099 144540.1077507012 1.3765276705016938 1.1142445256087394 0.9959547250750465 0.9256469748803794 1.1246464269760217 0.7943711653135528 0.7994719544081532 0.9477959102826252 0.7893369441050352 1.0 17.141110349337126 -1.522878745280861 0.5587617704346621 0.8818163924663442 24.22054515365825 0.6988180638955154 0.09564928657927044 77.10949860778153 0.6867531806198943 0.04670715634951222 2167.0561527990553 0.029999999999963844 1.522878745280861 23.338728761191906 KTS(ph)LDVSNSAEPGFLAPGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KTSLDVSNSAEPGFLAPGAR 20 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 KT(0.414)S(0.586)LDVSNSAEPGFLAPGAR;KT(0.252)S(0.747)LDVS(0.001)NSAEPGFLAPGAR 103.73 7.7942e-05 78294000.0 135070.0 128924.0 141984.0 143467.0 152234.0 114166.0 81674.0 98712.0 104146.0 78175.0 True False 157934.68324589718 141722.7226909668 145369.43703731874 135429.00911628964 122404.84052091301 108178.93398224335 73937.24745144646 96120.9145940094 105668.93822512518 92347.50866704047 1.7102213749515613 1.5346675263536234 1.5741565650834086 1.4665150264592388 1.3254807009709861 1.1714331609343485 0.8006414955711222 1.040860939092293 1.1442532641147387 1.0 16.494785420538562 -6.527908397694752 1.3570646205719474 0.9975489216818375 1.5992484514155214 0.8777724175242021 0.09693836068369593 0.14146359648661141 0.5385115397275474 0.04299324990453551 0.04774859715417901 2.965456803949266e-07 6.527908397694752 0.6016995297336839 KTS(ph)LDVSNSAEPGFLAPGAR ddPTM_PC-9_Lapatinib_30min_R1 2 KTSLDVSNSAEPGFLAPGAR 20 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 KT(0.004)S(0.996)LDVSNSAEPGFLAPGAR;KT(0.04)S(0.957)LDVS(0.002)NSAEPGFLAPGAR 208.87 3.5566e-21 19002400.0 109733.0 91545.0 96781.0 79665.0 76788.0 63386.0 58516.0 56319.0 75242.0 79281.0 True False 108168.18729743238 91333.0331770082 88824.03976546365 85523.82985464955 72271.48081101649 60675.12853998283 61545.67215901307 58935.786342617735 66767.45362661433 92984.6152147079 1.163291228851833 0.982238115048537 0.9552552275488027 0.9197632281121896 0.7772412742058097 0.6525286833728329 0.6618909162219994 0.6338229846575257 0.7180483940536149 1.0 16.504704414162276 -5.855594006299018 1.0563545091188171 0.7043352726424748 1.094480903722301 0.6106633864074853 0.10767250602208885 0.3537747457495599 0.7777823172782135 0.04069172293505145 0.10277224825999748 1.3944597836872458e-06 5.855594006299018 0.39014563107982614 KTS(ph)LS(ph)SS(ph)S(ph)SLGPK ddPTM_PC-9_Lapatinib_30min_R1 1 KTSLSSSSSLGPK 13 1 A8MWA6 A8MWA6 FAM90A22P Putative protein FAM90A22P 4 KT(0.252)S(0.751)LS(0.612)S(0.612)S(0.765)S(0.742)S(0.265)LGPK 49.395 0.037331 7592500.0 23241.0 18943.0 22430.0 23238.0 20509.0 23231.0 15615.0 18134.0 26258.0 18650.0 True False 22909.579078122584 18899.138647354444 20585.89198230386 24947.000039695526 19302.70094224538 22237.464284105994 16423.468295218216 18976.57184142172 23300.54753100181 21873.62765043707 1.0473607507744522 0.8640148286960901 0.9411283903743567 1.140505838280421 0.882464548209482 1.0166335753485158 0.7508342263881432 0.8675548539404042 1.06523471567535 1.0 14.416904884767956 KTS(ph)PASLDFPESQK ddPTM_PC-9_AZD4547_30min_R2 3 KTSPASLDFPESQK 14 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 KT(0.001)S(0.999)PASLDFPESQK;KT(0.012)S(0.596)PAS(0.392)LDFPESQK;KT(0.081)S(0.581)PAS(0.338)LDFPESQK 231.41 5.5117e-21 25718000.0 133790.0 127654.0 170588.0 185228.0 171907.0 145224.0 155004.0 171841.0 135655.0 165316.0 True False 176332.4369951235 168915.65908997317 168325.89165978084 142526.5463440726 148040.6803808157 136143.1203225579 168799.0557174637 145286.92196334343 142825.44635482854 159528.33715827452 1.1053361436355784 1.0588442285484685 1.05514728391344 0.8934246346632839 0.9279898669910823 0.853410263955079 1.0581133027795013 0.9107279907217888 0.8952982830450094 1.0 17.283453188374033 -5.68106108471993 5.795609886705154 0.9321464067393598 1.0751679869318356 0.5650393935465048 0.05600008765970418 0.14875385221743304 8.155223117700476 0.015213597697126215 0.026524856931415725 2.084197714307861e-06 5.68106108471993 0.1430215801924758 KTS(ph)PASLDFPESQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 KTSPASLDFPESQK 14 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 KT(0.002)S(0.705)PAS(0.281)LDFPES(0.012)QK;KT(0.005)S(0.994)PASLDFPESQK;KT(0.105)S(0.895)PASLDFPESQK;KT(0.004)S(0.996)PASLDFPESQK 172.32 1.4636e-19 57370000.0 198931.0 209655.0 200651.0 250927.0 269108.0 265101.0 280844.0 271984.0 254760.0 214158.0 True False 232606.08923365356 230468.16283837552 205435.28081315514 236868.37370631058 216378.21920794138 251198.63687636168 254240.42318551836 264844.7081908692 258485.38304143166 252983.15012620494 0.9194528928808661 0.9110020280931855 0.812051240213707 0.9363009891692184 0.85530684197741 0.9929461181546951 1.0049697897219092 1.046886751385406 1.021749404703364 1.0 17.94868177224612 -6.869207261154631 4.7906883074401945 1.019255949124033 0.8869901602510554 0.767574982436665 0.03494488417964658 0.10020139189706125 3.7976480135102504 0.012454994109499 0.010998117699264726 1.3514274588367227e-07 6.869207261154631 -0.13226578887297757 KTS(ph)PASLDFPESQK ddPTM_PC-9_Lapatinib_30min_R1 1 KTSPASLDFPESQK 14 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 KT(0.003)S(0.989)PAS(0.009)LDFPESQK 108.36 0.0010182000000000001 7694000.0 53302.0 55448.0 61825.0 60768.0 62003.0 61238.0 59274.0 58609.0 69849.0 54400.0 True False 52541.903705610326 55319.61356271496 56741.9871514015 65237.081436105436 58356.10544258814 58618.993492750305 62342.91769009056 61332.18810267377 61981.87007742198 63802.9675165564 0.823502507026434 0.8670382541119257 0.8893314740678383 1.0224772291222488 0.9146299571010574 0.918750267807514 0.977116270868013 0.9612748511541962 0.9714574805840833 1.0 15.961335905763057 -5.563990161061763 5.874198599129302 0.9612905372666766 0.8525547157814876 0.6990204264117693 0.032680069953888495 0.10242097223994959 8.90885100509132 0.009049270651534895 0.01615647634151566 2.729039608479615e-06 5.563990161061763 -0.10873582148518901 KTS(ph)QSEEEEAPR ddPTM_PC-9_AZD4547_30min_R2 3 KTSQSEEEEAPR 12 1 Q7RTP6;A0A5F9ZHV5;J3KSK6;Q7RTP6-2;Q7RTP6-4;Q7RTP6-3;Q7RTP6-5 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 KT(0.079)S(0.918)QS(0.002)EEEEAPR;KT(0.084)S(0.914)QS(0.002)EEEEAPR;KT(0.202)S(0.797)QS(0.002)EEEEAPR 144.51 8.313899999999999e-05 11228900.0 47106.1 44268.0 57683.9 71990.0 67068.0 64875.0 55588.1 66477.0 61906.9 53745.6 True False 62084.859932252 58576.76529207805 56918.973796009326 55393.8177344126 57756.765877948834 60818.355994366866 60535.33321158123 56204.50713949039 65179.172348558764 51863.98290288742 1.1970708082428345 1.1294305221748966 1.0974663072557906 1.0680594631178753 1.1136199467382855 1.1726510882946657 1.1671940684719577 1.0836905303769357 1.2567328751168867 1.0 15.662445381992132 -6.676410533199172 24.999788651998273 1.1432411782847818 1.1173273514905504 0.004718028565180665 0.06908286916682972 108.04988713808171 31753.07347044908 0.02185604704744052 0.021856029792005616 2.1066358316435595e-07 6.676410533199172 -0.025913826794231376 KTS(ph)QSEEEEAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 KTSQSEEEEAPR 12 1 Q7RTP6;A0A5F9ZHV5;J3KSK6;Q7RTP6-2;Q7RTP6-4;Q7RTP6-3;Q7RTP6-5 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 KT(0.04)S(0.959)QSEEEEAPR;KT(0.213)S(0.778)QS(0.009)EEEEAPR;KT(0.001)S(0.998)QS(0.001)EEEEAPR;KT(0.104)S(0.888)QS(0.008)EEEEAPR 139.86 9.0382e-05 15532200.0 43402.7 53455.4 62280.9 73314.0 86054.0 80659.0 83643.0 70969.0 75575.0 64026.0 True False 50749.91986759975 58762.0988375687 63765.91285762858 69206.45426719495 69192.33644380762 76429.10004794561 75719.72951712078 69106.13894787124 76680.14140114683 75633.40697046282 0.6709987279486055 0.7769331197855085 0.8430919009443953 0.9150249478279116 0.9148382866162484 1.0105203918394623 1.0011413282848898 0.9136986117108187 1.013839577940642 1.0 16.20673598734296 -4.686376771736256 0.5864012903313998 0.9885815763924733 0.4256502465618681 0.918323566952495 0.030847135658461092 1.0989731627616541 0.265003351646254 0.016298952434848978 0.43147662178012813 2.0588429911169754e-05 4.686376771736256 -0.5629313298306052 KTS(ph)QSEEEEAPR ddPTM_PC-9_Lapatinib_30min_R1 2 KTSQSEEEEAPR 12 1 Q7RTP6;A0A5F9ZHV5;J3KSK6;Q7RTP6-2;Q7RTP6-4;Q7RTP6-3;Q7RTP6-5 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 KT(0.125)S(0.686)QS(0.19)EEEEAPR;KT(0.182)S(0.81)QS(0.008)EEEEAPR 108.71 0.0020553 4538900.0 28304.0 30353.0 29816.0 29697.0 36541.0 43010.0 44248.0 44996.0 42263.0 38440.0 True False 27900.379769682084 30282.719493382774 27364.64357308835 31881.01644628791 34391.73022237012 41170.56256120692 46538.944932873244 47086.67842597395 37502.895890880085 45084.30278191964 0.6188490904393246 0.6716909794494412 0.6069661031569177 0.7071422752282929 0.7628315866107258 0.9131906233607705 1.0322649361572684 1.0444140315031627 0.8318393227081253 1.0 15.460337590399106 -6.621596294506845 1.6865154309572374 0.9827225709530518 0.6430589246867008 0.8646632836385121 0.05937346029460208 0.12296148142653224 0.718816590282578 0.023952839421686703 0.024310700661077305 2.3900319436600707e-07 6.621596294506845 -0.33966364626635104 KTSAS(ph)DVTNIYPGDAGK ddPTM_PC-9_Lapatinib_30min_R1 1 KTSASDVTNIYPGDAGK 17 1 Q15042-4;Q15042;Q15042-3 Q15042-4 RAB3GAP1 Rab3 GTPase-activating protein catalytic subunit 1 KT(0.001)S(0.052)AS(0.947)DVTNIYPGDAGK 178.99 4.373e-06 4451700.0 12659.0 11029.0 18147.0 19373.0 36192.0 45009.0 46312.0 47189.0 54524.0 46004.0 True False 12478.480338623713 11003.463028119735 16655.02370944575 20797.755046433493 34063.25771620969 43084.06999110355 48709.80875364367 49381.57321191407 48382.93295682622 53955.73010352319 0.2312725694691118 0.20393502241574216 0.3086794243630894 0.38545961673634077 0.6313186319757619 0.7985077749562369 0.9027736008795668 0.9152238903480163 0.8967153787743283 1.0 15.719488561745672 -6.410025666467616 1.0181071276308493 0.9406318045481377 0.20632464093651343 0.9916876251861676 0.027286027746348047 0.04040801486033661 0.08937168653804008 0.01266626462559554 0.01664403277410348 3.890221534068393e-07 6.410025666467616 -0.7343071636116243 down KTSAVS(ph)SPLLDQQR ddPTM_PC-9_AZD4547_30min_R2 1 KTSAVSSPLLDQQR 14 1 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 KTS(0.273)AVS(0.509)S(0.217)PLLDQQR 154.81 0.00045069999999999995 8133200.0 17090.0 14142.0 20254.0 28122.0 26877.0 21478.0 17607.0 22793.0 17493.0 21564.0 True False 22524.26450591723 18713.124938117093 19985.4187262715 21638.907380568875 23145.59248079014 20134.977264693807 19173.98889072142 19270.865581034115 18417.6442673327 20809.050923570765 1.0824263244223027 0.899278155781743 0.9604195212782951 1.0398795918202168 1.1122848690121054 0.967606708189011 0.9214254393987146 0.9260809467867503 0.8850785331334223 1.0 14.344923546492863 -6.996920067457891 24.998701830377325 0.9294905502141327 1.013116712120569 0.2990935750405044 0.06173434168986047 128.92415107535146 1046418.163693171 0.022933549583338673 0.020125000639807857 1.0071170131715446e-07 6.996920067457891 0.08362616190643635 KTSAVS(ph)SPLLDQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KTSAVSSPLLDQQR 14 1 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 KTSAVS(0.629)S(0.37)PLLDQQR;KTS(0.008)AVS(0.666)S(0.325)PLLDQQR;KTS(0.021)AVS(0.521)S(0.457)PLLDQQR 191.93 1.4966e-06 19970500.0 101790.0 78561.0 109368.0 121140.0 135035.0 128221.0 116167.0 123804.0 126031.0 95692.0 True False 119021.03655585888 86360.01688843843 111975.74790044964 114352.9185411792 108575.86110685836 121496.8650398299 105162.82078375218 120554.27618118098 127873.96494777266 113040.20210254482 1.052908915076855 0.7639761366500092 0.9905834014598669 1.0116128281285586 0.9605066081566572 1.0748111094990223 0.9303134533354191 1.0664725817795313 1.1312255513465141 1.0 16.78647642459213 -6.1430127647019805 0.7457601273526104 1.0472980833181844 0.9095592434250321 0.19548663583176518 0.0861958782859006 1.1733680006696119 1.3590815595325703 0.0476446639221865 0.09848004387224021 7.194278324049922e-07 6.1430127647019805 -0.13773883989315228 KTSAVSS(ph)PLLDQQR ddPTM_PC-9_AZD4547_30min_R2 1 KTSAVSSPLLDQQR 14 1 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 KT(0.023)S(0.236)AVS(0.178)S(0.562)PLLDQQR 134.4 1.0687000000000001e-05 27049000.0 78296.0 65256.0 101630.0 165120.0 147570.0 100460.0 94117.0 122790.0 85990.0 117680.0 True False 103192.49934203018 86348.72584936836 100282.31979613761 127054.13507856944 127082.45274361745 94178.22031898401 102493.23067121182 103815.62693349604 90535.25584793578 113560.05901900401 0.9087041714619147 0.7603793674932672 0.8830773835663083 1.1188276597963658 1.1190770226911426 0.8293252146269448 0.9025464723830393 0.9141913788202835 0.7972455864326816 1.0 16.793095978403954 -5.528421400596198 24.993960516825755 0.9542571195812346 0.8313383911583563 0.17750137718790449 0.10578373141088573 242.17302791137186 1092047.2096807153 0.030965055777977136 0.05384516631142085 2.9619559770589154e-06 5.528421400596198 -0.12291872842287832 KTSAVSS(ph)PLLDQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KTSAVSSPLLDQQR 14 1 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 KTSAVS(0.085)S(0.915)PLLDQQR 163.0 0.00025747 21758000.0 72078.0 59867.0 74101.0 101220.0 94400.0 99848.0 90379.0 83312.0 84526.0 67160.0 True False 84279.38179460849 65810.20011278045 75867.84886960725 95548.97155966777 75902.99765607019 94611.7951076418 81817.64683270408 81125.1482763607 85762.03284251876 79335.57636173266 1.062315113340003 0.8295168842376226 0.9562903850812879 1.2043647496050158 0.956733424485233 1.192551935039292 1.0312857180195472 1.0225569914116266 1.0810034637107129 1.0 16.275680336663193 -5.550248969269006 24.98075812253083 1.0703566643184572 0.932662844731889 0.2686425676395974 0.09062210204295842 225.58048518362844 205885.87413120107 0.02289468696358209 0.03965585352531999 2.8167676916616404e-06 5.550248969269006 -0.13769381958656823 KTSAVSS(ph)PLLDQQR ddPTM_PC-9_Lapatinib_30min_R1 2 KTSAVSSPLLDQQR 14 1 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 KTSAVS(0.231)S(0.769)PLLDQQR;KT(0.001)S(0.001)AVS(0.035)S(0.963)PLLDQQR 165.24 0.00071761 38887400.0 147587.0 91037.0 129442.0 96223.0 99153.0 99780.0 76461.0 71742.0 115096.0 81256.0 True False 145482.38231585926 90826.20941979675 118799.77842056967 103299.56041051808 93321.01548229826 95512.64199854048 80419.77645345361 75075.39522704737 102132.67646538894 95300.99133318574 1.5265568624279289 0.9530457988863461 1.2465744244488375 1.0839295474835955 0.9792239742400454 1.0022208653067919 0.8438503663859561 0.7877713985636642 1.0716853522364596 1.0 16.54020360086234 -1.522878745280366 0.49267351931983067 0.9290178909310054 15.77625942541042 0.5742231899731427 0.1301471244781189 77.80361670321173 0.8434043345053579 0.07265070517864497 1191.076988241617 0.02999999999999803 1.522878745280366 14.847241534479414 KTSDANET(ph)EDHLESLICK ddPTM_PC-9_AZD4547_30min_R2 2 KTSDANETEDHLESLICK 18 1 F2Z2T1;Q09161 F2Z2T1 NCBP1 Nuclear cap-binding protein subunit 1 1 KT(0.24)S(0.24)DANET(0.521)EDHLESLICK;KT(0.051)S(0.051)DANET(0.898)EDHLES(0.001)LICK 79.237 0.0034966000000000003 109597000.0 151329.0 161510.0 207878.0 217739.0 183540.0 203206.0 207175.0 223018.0 189682.0 196891.0 True False 199448.47416126062 213714.9489998085 205121.40189492787 167542.63758401544 158058.63913101275 190499.4966965905 225613.1736488447 188555.69254380997 199708.20327652193 189997.9060189563 1.0497403805143064 1.1248279177270823 1.079598223963914 0.881813074125667 0.831896742668538 1.0026399800300123 1.187450842886316 0.9924093191058514 1.0511073909235442 1.0 17.53562399303138 -5.558093864418582 24.98611232263587 0.9929907334364673 1.0910165850056388 0.17813551042010356 0.09082595055171362 313.3598182132726 222336.19954999798 0.027569208862139802 0.04775156356647909 2.7663436886904887e-06 5.558093864418582 0.09802585156917154 KTSDANET(ph)EDHLESLICK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KTSDANETEDHLESLICK 18 1 F2Z2T1;Q09161 F2Z2T1 NCBP1 Nuclear cap-binding protein subunit 1 1 KT(0.102)S(0.102)DANET(0.688)EDHLES(0.108)LICK 56.48 0.031314 22995000.0 16335.0 23345.0 21281.0 27184.0 31726.0 33444.0 51082.0 38962.0 35443.0 32262.0 True False 19100.192869043676 25662.53731826986 21788.41974864193 25660.968611717097 25509.5180469966 31690.13776520282 46243.143158346356 37939.288783651384 35961.28682343168 38110.84521414851 0.5011747381019196 0.6733657355030986 0.5717117955849759 0.6733245738194901 0.669350624570412 0.8315254512759527 1.2133853998383315 0.9954984879098552 0.9435971997304636 1.0 15.217913983835421 -6.918766629820388 2.883277460317603 1.0382220068119385 0.6176992323540781 0.8468073148048534 0.08401431652272487 0.09729673712317326 1.636612018408338 0.03255443121266888 0.027655164736658598 1.2056836461023514e-07 6.918766629820388 -0.42052277445786046 KTSDANET(ph)EDHLESLICK ddPTM_PC-9_Lapatinib_30min_R1 1 KTSDANETEDHLESLICK 18 1 F2Z2T1;Q09161 F2Z2T1 NCBP1 Nuclear cap-binding protein subunit 1 1 KT(0.162)S(0.162)DANET(0.676)EDHLES(0.001)LICK 69.581 0.0092171 46435000.0 14469.0 26932.0 28328.0 21774.0 45619.0 59994.0 66570.0 65733.0 61831.0 55239.0 True False 14262.669406710364 26869.640608697155 25998.981189242248 23375.332595934702 42935.780110404805 57428.19647284465 70016.66887048834 68787.19515011425 54866.94167070504 64786.98754865917 0.2201471305638063 0.4147382310146206 0.4012994302245547 0.36080289392030046 0.6627222801207926 0.8864156005048452 1.0807211682423319 1.0617439975651077 0.8468821247398863 1.0 15.98341645679254 -6.565984326372668 1.790296197131878 1.003190240072572 0.3468268333983862 0.9345016069471357 0.07842448892347062 0.08145499569665349 0.5313335316989991 0.03069009402209792 0.03240536025774927 2.7165373065228266e-07 6.565984326372668 -0.6563634066741859 down KTSFDQDS(ph)DVDIFPSDFPTEPPSLPR ddPTM_PC-9_AZD4547_30min_R2 1 KTSFDQDSDVDIFPSDFPTEPPSLPR 26 1 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 KT(0.027)S(0.027)FDQDS(0.946)DVDIFPSDFPTEPPSLPR 69.084 0.00014568 6858500.0 59909.0 54674.0 67982.0 98442.0 77913.0 77860.0 69489.0 73467.0 64919.0 77102.0 True False 78958.81581538882 72346.301291657 67080.51426135036 75747.7178137388 67096.12482627535 72991.4018916593 75673.38638196983 62114.36325371089 68350.48580523478 74402.68244802224 1.0612361438789455 0.9723614648194729 0.9015873091432267 1.018077780551208 0.9017971209996191 0.9810318592028069 1.0170787381870983 0.8348403741639829 0.9186562037327682 1.0 16.183067015462008 -4.803876435043095 3.586356767206096 0.9449683196731664 1.0717245366869819 0.27133806000391236 0.05613420974954046 0.34620674356837355 7.542081546849312 0.014138535880869885 0.11425705009572197 1.5708096656850607e-05 4.803876435043095 0.12675621701381545 KTSFDQDS(ph)DVDIFPSDFPTEPPSLPR ddPTM_PC-9_Lapatinib_30min_R1 3 KTSFDQDSDVDIFPSDFPTEPPSLPR 26 1 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 KT(0.022)S(0.007)FDQDS(0.971)DVDIFPSDFPTEPPSLPR;KT(0.079)S(0.029)FDQDS(0.892)DVDIFPSDFPTEPPSLPR;KT(0.035)S(0.046)FDQDS(0.919)DVDIFPSDFPTEPPSLPR 106.58 3.7284e-10 10135700.0 100966.0 76194.0 92844.0 76154.0 72804.0 81851.0 74694.0 74918.0 81761.0 64068.8 True False 99526.20632510335 76017.57747434531 85210.72470820423 81754.61920229672 68521.81185817116 78350.42353400019 78561.28983945108 78398.96378160533 72552.21519850106 75143.00671369019 1.3244906036874198 1.0116387512145661 1.1339807712629073 1.0879870633044813 0.9118854149562168 1.0426841693004234 1.0454903693005688 1.0433301408915001 0.9655218545478148 1.0 16.197351223558744 -2.426955843883134 1.3511406791665646 1.0242524691117179 199.99782098652338 0.6720734539775264 0.06106003178958637 605.2533737032991 2.176708040680208 0.017725919804614312 372122.2050611869 0.003741486272326137 2.426955843883134 198.97356851741165 KTSLDVS(ph)NSAEPGFLAPGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KTSLDVSNSAEPGFLAPGAR 20 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 KT(0.001)S(0.028)LDVS(0.63)NS(0.34)AEPGFLAPGAR 175.01 4.1029999999999996e-09 7742300.0 81135.0 81851.0 67624.0 75044.0 81094.0 57964.0 58660.0 64484.0 48462.0 46529.0 True False 94869.55301070446 89976.62634558609 69236.41262544825 70839.52797593053 65204.21283814988 54924.265800209796 53103.30013837746 62791.363326445666 49170.66506890345 54964.339376638665 1.7260200720437766 1.63700005068793 1.2596605983201465 1.2888270609514365 1.1863003099399287 0.9992709168001771 0.966140969592874 1.1424018561593718 0.8945921233031742 1.0 15.746208287454094 -4.824026201344516 0.5292206546330119 0.9813283422618398 2.289659769024982 0.9122921628221303 0.07890590498695146 1.0795947231587806 0.238996306815323 0.04682228122738198 0.8745387253060158 1.499594361007787e-05 4.824026201344516 1.308331426763142 KTSPAS(ph)LDFPESQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KTSPASLDFPESQK 14 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 KT(0.025)S(0.41)PAS(0.56)LDFPES(0.005)QK 92.943 0.005799800000000001 21218000.0 86021.0 83839.0 83340.0 91143.0 104140.0 97830.0 100970.0 97247.0 69020.0 84378.0 True False 100582.65630780596 92161.9818473519 85327.14166870985 86036.55319959296 83734.51457524518 92699.62258012775 91405.3906405042 94694.36929171339 70029.28692698866 99675.06346411968 1.0091055155837747 0.9246242605155472 0.8560530457994171 0.863170287627294 0.8400748558879758 0.9300181947062125 0.917033683890331 0.9500306897301429 0.7025757947191807 1.0 16.604944998350852 -4.8502935434968055 2.94977006787855 0.8814939063324048 1.020825611447414 0.20633733419961864 0.07562202749081824 0.5155152441128985 7.084159936772503 0.018547725343622014 0.1593496141619936 1.411583120541358e-05 4.8502935434968055 0.13933170511500914 KTSSVSSISQVS(ph)PER ddPTM_PC-9_AZD4547_30min_R2 1 KTSSVSSISQVSPER 15 1 P42356 P42356 PI4KA Phosphatidylinositol 4-kinase alpha 1 KT(0.006)S(0.207)S(0.022)VS(0.017)S(0.017)IS(0.059)QVS(0.672)PER 75.566 0.021800999999999997 4048400.0 16473.0 20980.0 21325.0 25369.0 27019.0 17094.0 19016.0 31561.0 24007.0 25668.0 True False 21711.071340314487 27761.37471373897 21042.216566492516 19520.56899714285 23267.878231888542 16025.109477729582 20708.387161126742 26683.97264963004 25275.961008738133 24769.371132731158 0.8765289689419963 1.1207944911065613 0.8495256683641256 0.7880930400912622 0.9393810649129284 0.6469728033003395 0.8360481600504551 1.0772971387379657 1.0204522703984822 1.0 14.596269620147966 -7.759265264136687 24.98911350950305 1.036656048581091 0.8660307456011311 0.31288067697385524 0.11352754805676671 73.26453336013735 842130.9789955143 0.0603790074405755 0.03265831891269647 1.7407433143564485e-08 7.759265264136687 -0.17062530297995981 KTTLS(ph)LT(ph)CEMILLK ddPTM_PC-9_AZD4547_30min_R2 1 KTTLSLTCEMILLK 14 1 E5RHG9 E5RHG9 UQCRB 2 KT(0.001)T(0.183)LS(0.894)LT(0.923)CEMILLK 62.14 0.026728 23927000.0 9509.3 4921.7 10536.0 36199.0 25177.0 12095.0 9375.5 11117.0 7909.0 14523.0 True False 12533.059594272587 6512.543275910826 10396.285755899893 27853.879818974925 21681.60813665412 11338.697737986393 10209.901337249876 9399.12309324601 8327.053593456489 14014.554190457166 0.8942888531414461 0.46469856888814687 0.7418206540582621 1.9874966724193965 1.5470779763667137 0.8090658884966297 0.728521307099589 0.6706687180706818 0.594171850227428 1.0 13.774638231843777 -6.976356827286945 24.799086800592384 0.7277385242962621 1.1228155201216392 0.16936896474006924 0.40661966467708255 426.9541437911232 447826.30298234336 0.16314759188083486 0.14387548365986905 1.0559495579392101e-07 6.976356827286945 0.39507699582537714 KTTQSGQMS(ph)GEGK ddPTM_PC-9_AZD4547_30min_R2 1 KTTQSGQMSGEGK 13 1 F8WJN3;Q16630-3;Q16630;Q16630-2 F8WJN3 CPSF6 Cleavage and polyadenylation specificity factor subunit 6 1 KTTQS(0.001)GQMS(0.999)GEGK 57.803999999999995 0.044863 0.0 12483.0 10089.0 12448.0 20005.0 13542.0 16684.0 12965.0 12714.0 14110.0 15052.0 True False 16452.33433747014 13350.07194885189 12282.931386621294 15393.156324168976 11661.927051935107 15640.746842543595 14118.859883466985 10749.343438655185 14855.82579386408 14525.034061472239 1.1326881760029794 0.9191077895137647 0.8456387320427606 1.0597673133861654 0.8028846612393464 1.0768130922343784 0.9720362667456571 0.7400563326159695 1.0227739040742954 1.0 13.826253926329647 -4.7592192752798415 24.545684061369062 0.9317009465840497 1.1326885069471395 0.23090766943222207 0.10626904699532812 66.92904388469238 739753.6594277595 0.025139792161493372 0.16177421377003423 1.740927657094396e-05 4.7592192752798415 0.20098756036308985 KTTQSGQMS(ph)GEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KTTQSGQMSGEGK 13 1 F8WJN3;Q16630-3;Q16630;Q16630-2 F8WJN3 CPSF6 Cleavage and polyadenylation specificity factor subunit 6 1 KTTQSGQMS(1)GEGK 48.729 0.042678 1768100.0 12191.0 11889.0 9155.3 14563.0 15282.0 13474.0 12934.0 13255.0 10827.0 10583.0 True False 14254.695516774509 13069.261348336277 9373.597073668601 13747.082323883022 12287.601802754903 12767.399720378626 11708.797885949109 12907.070294833395 10985.324392328386 12501.614125018092 1.1402284036465475 1.0454059145996368 0.749790945387625 1.0996245913855647 0.9828812247664156 1.0212601023118004 0.936582889925997 1.032432305601555 0.8787124832420381 1.0 13.609826757622415 -7.67236770243885 1.3753599511508539 0.9564418082902671 0.9983507515146557 0.030596897783175203 0.10489659691710318 2.4121341452411564 8.529919993746933 0.08288276249177616 0.0343303836511432 2.1263379852368992e-08 7.67236770243885 0.04190894322438854 KTTQSGQMS(ph)GEGK ddPTM_PC-9_Lapatinib_30min_R1 1 KTTQSGQMSGEGK 13 1 F8WJN3;Q16630-3;Q16630;Q16630-2 F8WJN3 CPSF6 Cleavage and polyadenylation specificity factor subunit 6 1 KTTQSGQMS(1)GEGK 80.508 0.0047191 1795500.0 13427.0 15497.0 13329.0 12586.0 14225.0 10256.0 13261.0 11486.0 13395.0 13686.0 True False 13235.528517789764 15461.117648632835 12233.141071427906 13511.6164256652 13388.31346742604 9817.37478790371 13947.589693428663 12019.681491704529 11886.31404439672 16051.606864551306 0.8245609694702511 0.9632130776126521 0.7621131750020506 0.8417609862788583 0.8340793280324516 0.6116132092410386 0.8689217105254928 0.7488148440919667 0.7405061776492108 1.0 13.970430106771287 -6.546989077535289 24.9968425068313 0.7762776316329639 0.8485070711867914 0.04496789942429136 0.10441412535797641 547.6307597988881 567762.5770649615 0.03270174086469893 0.032702965116601 2.837990402731403e-07 6.546989077535289 0.07222943955382743 KTVFS(ph)PTLPAAR ddPTM_PC-9_AZD4547_30min_R2 1 KTVFSPTLPAAR 12 1 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 KT(0.133)VFS(0.637)PT(0.23)LPAAR 58.824 0.030561 8176200.0 31774.0 30674.0 58060.0 84729.0 65177.0 55638.0 42773.0 60946.0 45282.0 53236.0 True False 41877.47105974334 40588.770637236885 57290.08646426994 65196.03810000068 56128.2985869129 52158.94706457928 46579.714137719515 51528.1960997545 47675.51407496483 51372.223843777276 0.8151773064583023 0.7900917577690849 1.1151957649037905 1.2690912174302902 1.0925806668910971 1.0153141748972057 0.9067100984253327 1.0030361203838778 0.9280406902365347 1.0 15.648700907175256 -5.253080599235244 24.867046324480373 1.0455942316604876 0.8026344943274175 0.488487617846033 0.0975869865606228 530.8569602414325 1579269.256821911 0.028479037843000016 0.07263972952369525 5.583665597704675e-06 5.253080599235244 -0.24295973733307008 KTVFS(ph)PTLPAAR ddPTM_PC-9_Lapatinib_30min_R1 1 KTVFSPTLPAAR 12 1 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 KT(0.007)VFS(0.917)PT(0.076)LPAAR 52.372 0.044129 5880900.0 44135.0 32374.0 40918.0 29032.0 33231.0 28611.0 31762.0 30942.0 38303.0 30886.0 True False 43505.62680663227 32299.03999205264 37553.87998804766 31167.11012791294 31276.41791465973 27387.37422549853 33406.480947340424 32379.678279324526 33988.91279152878 36224.60394699191 1.2009966173900701 0.8916326604789491 1.0366953919772566 0.8603851176266912 0.8634026188506313 0.7560434412360987 0.922204173611524 0.8938587244930619 0.9382825231509873 1.0 15.144682296058107 -2.0992459339609746 1.1645001854437407 0.8906957782040307 199.9999467981653 0.5581280401444464 0.07630555060023032 757.6694537602285 2.067923272711704 0.022793943772530682 401716.5139732654 0.00795708625848388 2.0992459339609746 199.10925101996128 KVAGAAT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 KVAGAATPK 9 1 P16402 P16402 HIST1H1D Histone H1.3 1 KVAGAAT(1)PK 67.252 0.039264999999999994 301570000.0 1212000.0 1099000.0 815760.0 992370.0 937310.0 924260.0 1134900.0 837080.0 1474700.0 1739300.0 True False 1597390.7888339215 1454230.257883658 804942.4893918849 763594.4284636622 807180.6856482994 866465.8760902265 1235903.9014073783 707728.5201847963 1552649.6313402813 1678407.6364017187 0.9517299338905021 0.8664344860830906 0.4795870037374078 0.45495171250573335 0.4809205273748556 0.5162428109227466 0.7363550275885248 0.4216666469071074 0.9250730261624371 1.0 20.678661716325912 -8.404372304940736 5.843264180276247 0.9961990658887304 0.6093335598925946 0.39534521084187835 0.1735484989625385 0.23628084745193473 9.646181349813828 0.17904466752000023 0.04646107796637254 3.941192930091349e-09 8.404372304940736 -0.3868655059961358 KVAS(ph)PSPSGSVLFTDEGVPK ddPTM_PC-9_AZD4547_30min_R2 2 KVASPSPSGSVLFTDEGVPK 20 1 P56181-2 P56181-2 NDUFV3 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial 1 KVAS(0.892)PS(0.08)PS(0.025)GS(0.002)VLFTDEGVPK;KVAS(0.868)PS(0.126)PS(0.005)GS(0.001)VLFTDEGVPK 71.857 0.0016296 23858100.0 98629.0 109199.0 125715.0 148853.0 138104.0 136181.0 119351.0 140542.0 123591.0 121391.0 True False 129990.97038935695 144495.44124716803 124047.9369592783 114537.24060592482 118930.64344856363 127665.5805421022 129973.00778647629 118824.46323387441 130123.76794397274 117141.1380385445 1.1096953006089485 1.2335157713733564 1.058961343865903 0.9777712810698247 1.0152764898820628 1.089844120347326 1.1095419590657345 1.0143700601130923 1.1108289549069976 1.0 16.83788828999986 -5.354062404606315 7.166947011252506 1.0471727507856448 1.1710045322168516 0.48305026002437423 0.05160520899442583 0.1998159678001542 13.274057256541942 0.013565510293373604 0.028484378429720396 4.425247805602213e-06 5.354062404606315 0.12383178143120688 KVAS(ph)PSPSGSVLFTDEGVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KVASPSPSGSVLFTDEGVPK 20 1 P56181-2 P56181-2 NDUFV3 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial 1 KVAS(0.985)PS(0.011)PS(0.003)GS(0.001)VLFTDEGVPK 76.237 0.0010029 11852000.0 116680.0 96392.0 88293.0 119480.0 132070.0 104910.0 123030.0 107070.0 93748.0 99633.0 True False 136431.61946495352 105961.16072746487 90398.23997306703 112785.92295938614 106191.83157242787 99408.33491649997 111375.70773993507 104259.52595004265 95118.88714620848 117695.67420560612 1.1591897526039658 0.9002978354358048 0.7680676506015643 0.958284352595296 0.902257727730232 0.844621823082814 0.9463024745104012 0.8858399142852824 0.8081765773314865 1.0 16.844701770881088 -4.7642533768520305 5.858288418512067 0.8850932801467251 1.1696638836473507 0.5969308981861524 0.06623331180259333 0.08767972912852122 10.993837944275803 0.015756587597108997 0.10045730269692753 1.7208642923760273e-05 4.7642533768520305 0.2845706035006257 KVASGVLS(ph)PPPAAPPPSSSSVPEAGGPPIKK ddPTM_PC-9_AZD4547_30min_R2 1 KVASGVLSPPPAAPPPSSSSVPEAGGPPIKK 31 2 Q8IXM2-2;F8W038;F8W1H0;H0YIS7;Q8IXM2;Q8IXM2-3 Q8IXM2-2 BAP18;C17orf49;RNASEK-C17orf49 Chromatin complexes subunit BAP18 1 KVAS(0.013)GVLS(0.987)PPPAAPPPSSSSVPEAGGPPIKK 71.296 1.2209000000000001e-05 12587000.0 76002.0 70968.0 106880.0 141070.0 130920.0 114010.0 88779.0 131370.0 112100.0 136790.0 True False 100169.05506019434 93907.0181451205 105462.70136584865 108548.49100977342 112744.01784369715 106880.93667695993 96680.15901228794 111069.78508228196 118025.3771433142 132001.02373563577 0.7588505924075808 0.7114112867275347 0.7989536624887351 0.8223306754587619 0.8541147231516517 0.8096977860642586 0.7324197667278213 0.8414312399934586 0.8941247105756451 1.0 17.010189592903856 -14.5228787174322 0.11627421941888955 1.6748717812818108 0.6946610586320155 0.7167018756674866 0.04231990212934773 95.3051429646329 0.7226593597108653 15.018129446180925 0.4981556844865722 3.00000019236813e-15 14.5228787174322 -0.9802107226497953 KVASGVLS(ph)PPPAAPPPSSSSVPEAGGPPIKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KVASGVLSPPPAAPPPSSSSVPEAGGPPIKK 31 2 Q8IXM2-2;F8W038;F8W1H0;H0YIS7;Q8IXM2;Q8IXM2-3 Q8IXM2-2 BAP18;C17orf49;RNASEK-C17orf49 Chromatin complexes subunit BAP18 1 KVAS(0.152)GVLS(0.844)PPPAAPPPS(0.001)S(0.001)S(0.001)SVPEAGGPPIKK 40.532 0.020644 6293800.0 23940.0 19195.0 25090.0 31238.0 32670.0 33554.0 37335.0 32453.0 29819.0 28382.0 True False 27992.56916344695 21100.55274466436 25688.240754354858 29487.836134962443 26268.548023557294 31794.36917155887 33798.358518007575 31601.143136795785 30255.046462994367 33527.431928211634 0.8349153977371175 0.6293518927976501 0.7661857552752052 0.8795137127741037 0.7834941870824781 0.9483091111671311 1.0080807438629968 0.9425458891232592 0.9023967755053819 1.0 15.03305436204523 -6.355136499671031 0.9892684808200709 0.9648604144772962 0.7306582027546294 0.6399288763714187 0.06733027551390341 0.3407817394797669 0.7115625162963175 0.03258636729242006 0.04587439207113992 4.4143168263916864e-07 6.355136499671031 -0.23420221172266675 KVASGVLS(ph)PPPAAPPPSSSSVPEAGGPPIKK ddPTM_PC-9_Lapatinib_30min_R1 2 KVASGVLSPPPAAPPPSSSSVPEAGGPPIKK 31 2 Q8IXM2-2;F8W038;F8W1H0;H0YIS7;Q8IXM2;Q8IXM2-3 Q8IXM2-2 BAP18;C17orf49;RNASEK-C17orf49 Chromatin complexes subunit BAP18 1 KVAS(0.144)GVLS(0.855)PPPAAPPPSSSSVPEAGGPPIKK;KVAS(0.052)GVLS(0.948)PPPAAPPPSSSSVPEAGGPPIKK 57.711000000000006 0.00042311 15564000.0 137443.0 90925.0 113752.0 100149.0 110085.0 100924.0 84814.0 87141.0 102216.0 87903.0 True False 135483.03761604038 90714.4687489152 104399.7496554179 107514.2915472705 103610.01673543736 96607.71578533488 89205.25392191083 91189.88898386066 90703.35769780193 103096.91642661509 1.314132782162092 0.879895072453367 1.0126369757113944 1.0428468209696624 1.0049768734760123 0.9370572771116848 0.8652562754911063 0.8845064638647081 0.8797872995781114 1.0 16.653641657554488 -6.726176967226901 2.0255071998357717 0.8971909266676459 1.0463523098879637 0.30260234097545613 0.10623609692046845 0.42236033586106053 3.566722899711318 0.040664973960895114 0.038274572601180834 1.8785511848440558e-07 6.726176967226901 0.1491613832203178 KVDEGAGDSAAVASGGAQT(ph)LALAGSPAPSGHPK ddPTM_PC-9_AZD4547_30min_R2 1 KVDEGAGDSAAVASGGAQTLALAGSPAPSGHPK 33 1 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 KVDEGAGDSAAVAS(0.11)GGAQT(0.478)LALAGS(0.394)PAPS(0.019)GHPK 55.532 0.0030612 46098000.0 15088.0 16384.0 36224.0 47583.0 42798.0 40702.0 29796.0 43851.0 30628.0 44009.0 True False 19885.67015010409 21679.80759341751 35743.64609165886 36613.47450002164 36856.23644725437 38156.89750570665 32447.786277499577 37074.835545734524 32246.93355169873 42468.25830529708 0.468247838353751 0.5104943894229206 0.8416555686061782 0.8621374165338641 0.8678537316576809 0.8984803952025348 0.7640479636399959 0.873001084226479 0.7593184848759517 1.0 15.374097322097828 -5.248599017309345 4.551785645045949 0.8537628928847214 0.47949762453979716 0.841268202379388 0.0641990911398545 0.06395580092817466 3.5913840164610216 0.015755215499292693 0.04093531592571576 5.641583009688053e-06 5.248599017309345 -0.37426526834492424 KVDEGAGDSAAVASGGAQT(ph)LALAGSPAPSGHPK ddPTM_PC-9_Lapatinib_30min_R1 1 KVDEGAGDSAAVASGGAQTLALAGSPAPSGHPK 33 1 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 KVDEGAGDSAAVAS(0.186)GGAQT(0.599)LALAGS(0.208)PAPS(0.007)GHPK 59.536 0.0016807000000000002 6744000.0 27998.0 21955.0 26737.0 21572.0 31969.0 30760.0 27120.0 27519.0 26003.0 18805.0 True False 27598.74338579562 21904.164546411175 24538.78706780463 23158.47684208245 30088.646273472255 29444.466505062195 28524.140900820854 28797.633203048666 23074.26831627086 22055.41919391256 1.2513361520425355 0.9931420642622322 1.1125967206543732 1.0500129985502313 1.364229172383036 1.3350218486524645 1.2932939814036137 1.305694212830786 1.0461949561420945 1.0 14.428845560665662 -6.243874267928129 24.77272755174321 1.2483656344854122 1.0947858937195423 0.16233338895044025 0.12882490392117057 1057.200838082217 1491008.7952605186 0.036983330610969666 0.04763251425740544 5.703293637483885e-07 6.243874267928129 -0.1535797407658699 KVDEGAGDSAAVASGGAQTLALAGS(ph)PAPSGHPK ddPTM_PC-9_AZD4547_30min_R2 3 KVDEGAGDSAAVASGGAQTLALAGSPAPSGHPK 33 1 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 KVDEGAGDSAAVASGGAQT(0.003)LALAGS(0.991)PAPS(0.005)GHPK;KVDEGAGDSAAVAS(0.021)GGAQT(0.303)LALAGS(0.668)PAPS(0.008)GHPK;KVDEGAGDSAAVASGGAQT(0.006)LALAGS(0.973)PAPS(0.021)GHPK 117.97 4.4395e-24 59875100.0 109019.0 97885.0 203717.0 283770.0 259913.0 243378.0 154706.0 246505.0 172872.0 224938.0 True False 143684.7742639312 129524.41200449657 201015.57947367703 218351.21070279594 223828.56637495308 228159.53518608148 168474.53429476617 208413.3163713781 182009.66099481704 217062.98908579908 0.6619496712409896 0.596713481879212 0.9260702633843352 1.005934782444591 1.0311687281081334 1.051121318042369 0.7761550460736205 0.9601513240426169 0.8385108016865721 1.0 17.7277542307248 -5.285854157414719 6.975507171599168 0.9503057764572904 0.6288148679428229 0.7063650256288074 0.08236142080803555 0.09057818608024833 19.105060665884967 0.0224187902787953 0.0491663514065878 5.177806812585454e-06 5.285854157414719 -0.3214909085144675 KVDEGAGDSAAVASGGAQTLALAGS(ph)PAPSGHPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KVDEGAGDSAAVASGGAQTLALAGSPAPSGHPK 33 1 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 KVDEGAGDSAAVASGGAQT(0.007)LALAGS(0.987)PAPS(0.006)GHPK;KVDEGAGDSAAVASGGAQT(0.013)LALAGS(0.982)PAPS(0.005)GHPK 116.14 5.5654e-24 50366000.0 107856.0 136341.0 194006.0 210366.0 255580.0 228478.0 203283.0 193339.0 200035.0 155673.0 True False 126113.89054689804 149876.03343372178 198631.83881185195 198579.87503577385 205500.93369638102 216496.2114674684 184026.56259853076 188264.05610960312 202960.13344596 183895.2825932102 0.6857918744216576 0.8150074940489829 1.080135585920603 1.0798530132773827 1.1174888817075537 1.177279854135105 1.000713884573162 1.023756854742473 1.1036723214641815 1.0 17.4885249456675 -5.1240331345825 2.7618299238602493 1.0783706508265818 0.6945704881793426 0.8595885333977229 0.05320312383748086 0.09989633660667233 1.3977958561821375 0.014869761973997676 0.05954820148967355 7.515655509899206e-06 5.1240331345825 -0.38380016264723915 KVDEGAGDSAAVASGGAQTLALAGS(ph)PAPSGHPK ddPTM_PC-9_Lapatinib_30min_R1 2 KVDEGAGDSAAVASGGAQTLALAGSPAPSGHPK 33 1 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 KVDEGAGDSAAVASGGAQT(0.086)LALAGS(0.903)PAPS(0.011)GHPK;KVDEGAGDSAAVASGGAQT(0.034)LALAGS(0.961)PAPS(0.005)GHPK 98.03299999999999 4.0954e-16 74449000.0 137081.0 100897.0 173887.0 114865.0 139542.0 158709.0 115714.0 119319.0 181920.0 92966.0 True False 135126.1998024233 100663.37919559311 159590.6820832308 123312.55527840737 131334.4139101274 151921.38603874884 121705.10472704965 124862.99633542525 161430.2538974733 109035.0492305914 1.239291409101429 0.9232203764379143 1.4636640530672156 1.130944188575743 1.2045155648288512 1.3933261562294508 1.116201676303765 1.1451638460891629 1.4805354336666054 1.0 16.73443243717474 -5.2471092420324785 24.99719099032933 1.2426144456427812 1.081255941664342 0.12980879666251977 0.16625107065917638 1572.2432206198785 2742576.953239742 0.03957268398188875 0.1036362764766673 5.66096875642987e-06 5.2471092420324785 -0.16135850397843932 KVDLTLLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 KVDLTLLSPK 10 1 E7EVA0;P27816-4;B5MEG9 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 KVDLT(0.008)LLS(0.992)PK;KVDLT(0.056)LLS(0.944)PK 58.32 0.035492 21030000.0 309050.0 260020.0 266650.0 321610.0 325580.0 328960.0 277660.0 288840.0 282560.0 310110.0 True False 407321.4713606617 344066.3800317638 263114.0467739853 247467.78332496804 280378.8369198816 308390.07919702335 302371.20210130734 244206.41488289766 297495.54474232683 299253.1432901381 1.3611267934644447 1.1497502624330915 0.8792356995190709 0.8269513249023351 0.9369286278408206 1.0305324642756606 1.0104194688713635 0.8160529650514969 0.9941267165033344 1.0 18.191006875441104 -4.98501031661779 2.897172558349897 0.9329614559527177 1.3627923287955177 0.7735590073335229 0.07314216114493967 0.13595358382725994 2.106078263807845 0.020232232046289822 0.11048732785926774 1.035117577282756e-05 4.98501031661779 0.42983087284279997 KVDLTLLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 KVDLTLLSPK 10 1 E7EVA0;P27816-4;B5MEG9 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 KVDLTLLS(1)PK 85.163 0.0055381 11079000.0 173220.0 146920.0 127530.0 123610.0 150690.0 138240.0 145300.0 142690.0 138560.0 138300.0 True False 170749.8510353424 146579.81576673783 117044.9756800363 132700.6917508723 141826.71046793868 132327.7974531795 152822.9230416397 149319.89831545498 122953.91369851521 162204.97072683374 1.052679521905028 0.9036703074506272 0.7215868610904007 0.818104964084923 0.8743672270487093 0.8158060561290084 0.9421593084160524 0.9205630237246042 0.7580156954966536 1.0 17.307458505663213 -7.260253344940405 24.99933257483599 0.8985647569135672 0.8580170092255422 0.03644860550036633 0.09729364122620797 479.92031403831095 10115941.790455893 0.039940242023052075 0.02917983229596178 5.492203936172198e-08 7.260253344940405 -0.04054774768802494 KVDT(ph)TPNQGK ddPTM_PC-9_AZD4547_30min_R2 1 KVDTTPNQGK 10 1 Q9P2E9;A2A2S5 Q9P2E9 RRBP1 Ribosome-binding protein 1 1 KVDT(0.606)T(0.394)PNQGK 72.49600000000001 0.025817000000000003 6870400.0 65552.0 46588.0 57523.0 58940.0 57068.0 57828.0 48433.0 51978.0 53972.0 67266.0 True False 86396.17243369718 61646.659922005296 56760.20743513948 45352.29361392251 49145.09326538417 54212.006018377564 52743.4431728466 43945.994435615765 56824.84973397819 64911.03781417693 1.330993546598754 0.9497099722620876 0.8744307493223091 0.6986838470177305 0.7571145820541881 0.8351739217846453 0.8125496825953865 0.6770188232303646 0.8754266092101723 1.0 15.986176202084822 -4.604416059132653 1.558191023203137 0.7957642529412072 1.7303485642193837 0.751732021845027 0.08891355399664704 0.7576633029802942 1.2524849553211879 0.023670587357549084 1.23542609981691 2.4864741059633662e-05 4.604416059132653 0.9345843112781764 KVDTT(ph)PNQGK ddPTM_PC-9_AZD4547_30min_R2 1 KVDTTPNQGK 10 1 Q9P2E9;A2A2S5 Q9P2E9 RRBP1 Ribosome-binding protein 1 1 KVDT(0.317)T(0.683)PNQGK 69.352 0.032774 5936700.0 84793.0 62269.0 64618.0 81387.0 70481.0 86404.0 79998.0 69715.0 76815.0 77177.0 True False 111755.41019603502 82396.23651333705 63761.12309934882 62624.484566615436 60695.92974061728 81001.14422099861 87117.66702333924 58942.14864132811 80875.28407906945 74475.05672085048 1.5005750262791988 1.1063601713279247 0.8561406450261605 0.8408786421116308 0.8149833301654201 1.0876278285306904 1.1697563031052953 0.7914347599929563 1.0859378648371962 1.0 16.184469696793755 -4.814533226026314 3.003508249138943 0.9522234766391533 1.5684294249311777 0.6371707361349033 0.12389726231682238 0.22584664161221202 3.1045262076453426 0.033064336634653566 0.32583286660298627 1.5327339389131986e-05 4.814533226026314 0.6162059482920244 KVDTT(ph)PNQGK ddPTM_PC-9_Lapatinib_30min_R1 3 KVDTTPNQGK 10 1 Q9P2E9;A2A2S5 Q9P2E9 RRBP1 Ribosome-binding protein 1 1 KVDT(0.337)T(0.663)PNQGK;KVDT(0.316)T(0.684)PNQGK;KVDT(0.303)T(0.697)PNQGK 89.74700000000001 0.0077694 100929900.0 311094.0 285464.0 248994.0 206840.0 235129.0 238181.0 252897.0 223055.0 276090.0 171743.0 True False 306657.742512347 284803.0256468555 228522.67446463564 222051.70359801254 221299.17450140018 227994.55385702933 265990.76922547567 233418.949602312 244993.83684341086 201428.5487168375 1.522414496186624 1.4139158895853607 1.1345098593044338 1.1023844684010828 1.098648507925737 1.131887983651898 1.3205216982394976 1.158817610955663 1.2162815966460454 1.0 17.61990864722202 -5.1478282101020065 3.4245512970717873 1.1531186732422356 1.504053534029982 0.7294166204607743 0.07956132014357245 0.1288288569212299 2.736721305843839 0.02137468324383131 0.07076261017605774 7.1149489752974125e-06 5.1478282101020065 0.3509348607877465 KVDWLTEK ddPTM_PC-9_Lapatinib_30min_R1 1 KVDWLTEK 8 1 I3L3H2;P38919;P60842;P60842-2;J3KT12;J3QL43;J3QS69;Q14240-2;E7EQG2;Q14240;J3KSZ0;J3KTN0;J3QL52 I3L3H2;P60842 EIF4A3;EIF4A1;EIF4A2 Eukaryotic initiation factor 4A-III;Eukaryotic initiation factor 4A-III, N-terminally processed;Eukaryotic initiation factor 4A-I;Eukaryotic initiation factor 4A-II;Eukaryotic initiation factor 4A-II, N-terminally processed 0 63.426 0.036741 4189500.0 33006.0 40271.0 43112.0 46113.0 37422.0 36787.0 39612.0 38704.0 33387.0 36102.0 False True 32535.328387440917 40177.75497374285 39567.49777713258 49504.303848458534 35220.91153448275 35213.7057646854 41662.91553699543 40502.32913589864 29626.60447930372 42342.1825971088 0.7683904416788966 0.9488824739158879 0.9344699623451702 1.1691486081267521 0.8318161552892576 0.8316459758286021 0.9839576748658264 0.9565479777290511 0.6996947880841334 1.0 15.369808016889003 KVEAPETNIDKT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 KVEAPETNIDKTPK 14 2 O75152;E9PBY7;E9PQ61 O75152 ZC3H11A Zinc finger CCCH domain-containing protein 11A 1 KVEAPETNIDKT(1)PK;KVEAPETNIDKT(1)PK 75.102 0.008439299999999999 88044000.0 528080.0 496950.0 396390.0 486250.0 550130.0 544390.0 541620.0 461660.0 551640.0 588620.0 True False 695998.4552536418 657579.369113088 391133.6096033755 374152.5749876111 473753.9454350217 510349.2072412068 589823.1307430316 390321.05489142245 580798.5642046202 568012.5929619839 1.2253222267912356 1.1576844902047774 0.688600243110373 0.6587047182115071 0.8340553559993507 0.8984822054382932 1.0383979828111092 0.6871697207557262 1.0225100136881862 1.0 19.11556338938228 -5.154195549510792 6.019479782699178 0.8434601454383873 1.2056047348919736 0.5023821069063806 0.134679977402965 0.17945332036154843 8.492114465075748 0.034925758038031315 0.09588753390175345 7.011395256684341e-06 5.154195549510792 0.3621445894535863 KVEAPETNIDKT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 KVEAPETNIDKTPK 14 2 O75152;E9PBY7;E9PQ61 O75152 ZC3H11A Zinc finger CCCH domain-containing protein 11A 1 KVEAPETNIDKT(1)PK 61.211999999999996 0.024971 34244000.0 440370.0 353410.0 319220.0 385300.0 356430.0 312540.0 290200.0 294330.0 265090.0 305850.0 True False 434090.24304603145 352591.70085844625 292974.96382483444 413636.24732312135 335465.48816834146 299173.39276632434 305225.13604049437 308005.64630449197 235232.7726785465 358715.7649804921 1.2101231265083607 0.9829278088115839 0.8167328911255606 1.153103062937911 0.9351846807920051 0.8340123907924542 0.8508829715278705 0.8586342624814444 0.655763687139145 1.0 18.45248162525047 -6.588432662573877 3.960223859975824 0.8324774563095751 1.0233262562701404 0.35801312194704826 0.12530460659397147 0.2625533182713304 8.293908128820759 0.04222602809673464 0.04280095135301822 2.579688914582944e-07 6.588432662573877 0.19084879996056525 KVEEAEPEEFVVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KVEEAEPEEFVVEK 14 1 Q13185;S4R2Y4;C9JMM0;B8ZZ43 Q13185 CBX3 Chromobox protein homolog 3 0 115.91 9.630700000000001e-05 5970300.0 80475.0 69178.0 73515.0 106240.0 100760.0 88266.0 80399.0 77198.0 93132.0 77461.0 False True 94097.8280462987 76045.53465852511 75267.87640718992 100287.71723472724 81016.801311712 83637.17557658748 72783.02468164687 75171.63429804215 94493.87931156598 91504.06611906142 1.0283458652412494 0.8310618083307655 0.8225631887139789 1.0959919213233311 0.8853901771566761 0.9140268746938759 0.7954075460094256 0.8215114091239599 1.0326741020296775 1.0 16.481548232667087 KVEEAEPEEFVVEK ddPTM_PC-9_Lapatinib_30min_R1 2 KVEEAEPEEFVVEK 14 1 Q13185;S4R2Y4;C9JMM0;B8ZZ43 Q13185 CBX3 Chromobox protein homolog 3 0 ; 195.5 8.134800000000001e-08 16648500.0 241240.0 230201.0 249270.0 222520.0 230740.0 207256.0 217712.0 224301.0 229890.0 230302.0 False True 237799.8733620019 229667.98372800753 228775.98281002592 238884.86310495992 217168.326852294 198392.14401733346 228984.06208700265 234722.84331105862 203997.36735097918 270109.3938418749 0.880383573409567 0.8502776614368983 0.8469752923289813 0.8844004264613093 0.8040013853773142 0.734488131625198 0.8477456442001884 0.8689917813390379 0.7552398102466645 1.0 18.043184289083477 -11.12187528962743 2.7246800003647853 1.013650662482567 0.8310115123448722 0.5252906920505499 0.04839855206523818 21934358.23189004 20865610.164836355 2141856.3088755463 0.013356384657412537 7.553090882489683e-12 11.12187528962743 -0.18263915013769472 KVEEEGS(ph)PGDPDHEASTQGR ddPTM_PC-9_AZD4547_30min_R2 1 KVEEEGSPGDPDHEASTQGR 20 1 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 KVEEEGS(0.97)PGDPDHEAS(0.015)T(0.015)QGR 58.913000000000004 0.0074923 15941000.0 13126.0 8249.4 12271.0 20390.0 16430.0 14534.0 12444.0 14912.0 13074.0 15801.0 True False 17299.79496223928 10915.857224190575 12108.278522271035 15689.4005223597 14148.978102443796 13625.186682421998 13551.491892777718 12607.693043670448 13765.064948900004 15247.811799450095 1.1345755830264896 0.7158966393187152 0.7940994210531713 1.0289607931103615 0.9279349908394116 0.8935830833715683 0.8887499446488739 0.8268526139681982 0.9027567450298957 1.0 13.896314597136879 -4.732958340652772 24.874362485524518 0.8842713742829412 1.1345770794512597 0.41980706807067936 0.0874420347150461 3297.1492114491566 2879452.3921702225 0.022319509252886182 2.3561688593835215 1.84944601708423e-05 4.732958340652772 0.2503057051683185 KVEEEGS(ph)PGDPDHEASTQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KVEEEGSPGDPDHEASTQGR 20 1 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 KVEEEGS(1)PGDPDHEASTQGR 57.051 0.0090271 6569200.0 7246.8 8232.8 11000.0 14294.0 14152.0 12274.0 12629.0 9911.4 9586.4 10351.0 True False 8473.540109175745 9050.097975320288 11262.281717732301 13493.153521773258 11379.017190982027 11630.329832857886 11432.689693957876 9651.236251996355 9726.582964312987 12227.554361529088 0.6929873185299915 0.7401396638884825 0.921057587211898 1.1035038669896293 0.9306045063911743 0.9511574832535427 0.934993978021308 0.7893022567424876 0.7954642994608329 1.0 13.577848258204632 -5.227135921829204 4.387130631739903 0.9287294487328451 0.7079988345537711 0.49547690364853714 0.08589750598657163 0.18574479407913594 8.505900780499973 0.024642792851261863 0.06745159345578867 5.9273978484153265e-06 5.227135921829204 -0.22073061417907403 KVEEEGS(ph)PGDPDHEASTQGR ddPTM_PC-9_Lapatinib_30min_R1 2 KVEEEGSPGDPDHEASTQGR 20 1 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 KVEEEGS(0.924)PGDPDHEAS(0.056)T(0.02)QGR;KVEEEGS(1)PGDPDHEASTQGR 101.42 0.00012446 29274000.0 30953.0 24626.0 24346.0 18263.0 27022.0 25830.0 25420.1 27702.8 29646.0 22815.9 True False 30511.604543915004 24568.98001001692 22344.365858277724 19606.121943582028 25432.619087296036 24725.31111267091 26736.228396495455 28989.973222043544 26306.955293780164 26759.597914724232 1.1402116220560348 0.9181371143285398 0.835003796749238 0.7326762534348071 0.9504111073844634 0.9239791715654302 0.9991266864956921 1.0833486106340957 0.9830848496906971 1.0 14.70776881799551 -7.2408610387547725 2.4805552450236705 1.0276543323607035 0.9026431608895045 0.19154964771935268 0.09918329356670959 0.47451765714137434 5.752310241383465 0.04901503025187892 0.03305593103247817 5.74300191696827e-08 7.2408610387547725 -0.125011171471199 KVEEEQEADEEDVS(ph)EEEAESK ddPTM_PC-9_AZD4547_30min_R2 1 KVEEEQEADEEDVSEEEAESK 21 1 Q9H3N1 Q9H3N1 TMX1 Thioredoxin-related transmembrane protein 1 1 KVEEEQEADEEDVS(0.996)EEEAES(0.004)K 126.47 5.0756999999999995e-06 9737300.0 51316.0 66488.0 63612.0 36396.0 40549.0 38731.0 67879.0 49960.0 56845.0 39648.0 True False 67633.42056089231 87978.94575629539 62768.4633166576 28005.464512594568 34919.471276688564 36309.1444472882 73920.09950095289 42239.829966589015 59849.71064863246 38259.935587912 1.767734825519693 2.2995058513400064 1.6405794299478365 0.7319788724747025 0.9126902787500031 0.949012168717813 1.932049763416421 1.1040225059849407 1.5642919866164549 1.0 15.223546824402368 -5.532083092056163 8.23314743689926 1.185864280703332 2.019214355083644 0.501270145262878 0.3492725264489711 0.10685122590456567 55.812235070893585 0.09764453646180489 0.17586132768673676 2.937087655411796e-06 5.532083092056163 0.8333500743803122 KVEEEQEADEEDVS(ph)EEEAESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KVEEEQEADEEDVSEEEAESK 21 1 Q9H3N1 Q9H3N1 TMX1 Thioredoxin-related transmembrane protein 1 1 KVEEEQEADEEDVS(0.991)EEEAES(0.009)K 81.055 0.00036698 7433000.0 25518.0 33459.0 20932.0 20447.0 41333.0 15818.0 26620.0 13249.0 15784.0 16799.0 True False 29837.693396526294 36780.58839717244 21431.098265052075 19301.420880068414 33234.09536142317 14988.476234002459 24098.36088788969 12901.227788475879 16014.811139605721 19844.525719189176 1.5035730164956256 1.8534375130772967 1.0799501367940842 0.9726320070932412 1.674723590359562 0.755295261075903 1.2143581171399402 0.6501151990748111 0.807014053458571 1.0 14.276453462131572 -5.164212428118216 0.4022237418256733 0.828049684506904 2.1092947603849472 0.4306295280973116 0.2904331025968588 3.918202371055737 0.6294102853579072 0.24940551754080417 2.3510222208483915 6.851530129678417e-06 5.164212428118216 1.2812450758780431 KVEEEQEADEEDVS(ph)EEEAESK ddPTM_PC-9_Lapatinib_30min_R1 3 KVEEEQEADEEDVSEEEAESK 21 1 Q9H3N1 Q9H3N1 TMX1 Thioredoxin-related transmembrane protein 1 1 KVEEEQEADEEDVS(0.984)EEEAES(0.016)K;KVEEEQEADEEDVS(0.973)EEEAES(0.027)K;KVEEEQEADEEDVS(0.984)EEEAES(0.016)K 119.87 9.8221e-07 42251000.0 75842.5 155643.0 69072.0 62922.0 57111.1 63054.0 88008.0 72703.0 92139.0 41211.3 True False 74760.97204218888 155282.61819617727 63393.16678563049 67549.49378163877 53751.93738274274 60357.327406053046 92564.62361354881 76081.04679535037 81761.33555331624 48334.61829439448 1.5467376112673088 3.2126584149354063 1.3115478930549949 1.397538579289302 1.112079484218799 1.2487390929298572 1.9150792305787967 1.574048776633739 1.6915688679970058 1.0 15.560769228072603 -5.295608949298414 24.891617283526926 1.4285459945939778 2.379698528849828 0.4250142023429133 0.4522716619505868 458.64027936534194 334106.4167543665 0.11260639587739776 0.23442675761298187 5.062803255623091e-06 5.295608949298414 0.95115253425585 KVEGNFNPFAS(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 2 KVEGNFNPFASPQK 14 1 Q5TH58;Q9H6K1-2;Q9H6K1 Q5TH58 C6orf106 Uncharacterized protein C6orf106 1 KVEGNFNPFAS(1)PQK;KVEGNFNPFAS(1)PQK 80.541 0.0052606 147284000.0 251620.0 280920.0 291988.0 409460.0 413680.0 342280.0 326235.0 378820.0 334112.0 411770.0 True False 331629.92597886967 371721.8963099879 288116.0483384297 315065.3230939378 356247.67263657576 320877.1774913585 355269.28299906256 320282.0734175992 351772.4782168329 397354.057633033 0.8345955442215182 0.9354928914637708 0.7250864633286632 0.79290828177451 0.8965497288707189 0.8075346692135633 0.8940874672712242 0.8060370021775093 0.8852872431007213 1.0 18.6000655512102 -8.604585945607857 4.657484347949545 0.9999834749534839 0.8378420025575363 0.4279531239614015 0.05730183831246592 0.4622381244054453 24.14000201222726 0.05471835018570267 0.014257795968402851 2.4855016420488387e-09 8.604585945607857 -0.16214147239594767 KVEGNFNPFAS(ph)PQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KVEGNFNPFASPQK 14 1 Q5TH58;Q9H6K1-2;Q9H6K1 Q5TH58 C6orf106 Uncharacterized protein C6orf106 1 KVEGNFNPFAS(1)PQK 64.89 0.018427000000000002 54323000.0 115830.0 118860.0 112590.0 139270.0 153750.0 140410.0 149300.0 150660.0 113820.0 103210.0 True False 135437.73125321875 130659.63528162602 115274.57259995265 131467.15341943174 123623.79120361016 133046.6524223218 135157.2231616049 146705.33463746475 115484.40217371548 121921.15599008968 1.1108632472630735 1.0716731991308108 0.9454845770107585 1.0782964806380115 1.0139650514276528 1.09125156616081 1.1085625137329824 1.2032803777663463 0.9472056037846507 1.0 16.895588961295246 -6.7812148499408496 24.660659855076965 1.0851714556222662 1.0420167695373235 0.009040217163698405 0.07606806487237396 620.399162387368 773652.4976842636 0.026256048933333366 0.023187808882465927 1.6549510396438512e-07 6.7812148499408496 -0.04315468608494277 KVEGNFNPFAS(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 1 KVEGNFNPFASPQK 14 1 Q5TH58;Q9H6K1-2;Q9H6K1 Q5TH58 C6orf106 Uncharacterized protein C6orf106 1 KVEGNFNPFAS(1)PQK 120.79 3.742e-05 55420000.0 256600.0 246040.0 260600.0 260690.0 264810.0 241140.0 218280.0 203620.0 243210.0 219970.0 True False 252940.83694532278 245470.30949665242 239174.47394509078 279862.0122363472 249234.39643649137 230827.0043247951 229581.47034775736 213080.92855135555 215817.12868516083 257991.52140839933 0.980423060279251 0.9514665759425253 0.9270633106057727 1.0847721301403814 0.9660565396719163 0.8947077138996249 0.8898799041706917 0.8259222139864413 0.8365279893966878 1.0 17.976964128368095 -6.776271557469556 3.6335024239319673 0.8762079212418821 0.9842914197150838 0.3818013578219007 0.058452170137182916 0.22516634182852172 6.337176118895357 0.021099288447489605 0.019492593554149635 1.6738958881080956e-07 6.776271557469556 0.10808349847320176 KVELS(ph)ESEEDKGGK ddPTM_PC-9_Lapatinib_30min_R1 1 KVELSESEEDKGGK 14 2 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 KVELS(1)ESEEDKGGK 90.654 0.013626 54438000.0 108430.0 82789.0 69807.0 77780.0 85354.0 90344.0 75875.0 77631.0 67974.0 62788.0 True False 106883.76831637337 82597.307157041 64067.737922812456 83500.20066647376 80333.64553242049 86480.19772215022 79803.43624077368 81238.01966589871 60318.0523220473 73640.82214024896 1.4514200848112915 1.1216239139717155 0.8700030236055137 1.133884688406216 1.090884691366224 1.1743513340664322 1.083684754208583 1.103165571823477 0.8190844502954021 1.0 16.168218112851054 -4.787998189472151 4.028281335449543 1.0474660934394364 1.4839564786942139 0.5698142013200224 0.10787355339150342 0.16379031628001203 5.011570051033395 0.02711480915359012 0.20467327023100518 1.6293028250170457e-05 4.787998189472151 0.43649038525477746 KVEPVPVT(ph)KQPTPPSEAAASK ddPTM_PC-9_Lapatinib_30min_R1 1 KVEPVPVTKQPTPPSEAAASK 21 2 Q86UP2-2;Q86UP2-3;Q86UP2-4;Q86UP2 Q86UP2-2 KTN1 Kinectin 1 KVEPVPVT(0.941)KQPT(0.057)PPS(0.002)EAAASK 54.833999999999996 0.008550499999999999 4958700.0 87951.0 40272.0 20693.0 16971.0 12267.0 15556.0 12398.0 11567.0 26888.0 7307.9 True False 86696.80261176209 40178.75265830432 18991.701417289943 18219.10395359639 11545.479177849931 14890.70614280714 13039.907776120102 12104.44504740957 23859.590296807706 8571.060777835335 10.115061001079239 4.687722290128442 2.2157935767299963 2.1256533381154856 1.3470303708155247 1.7373235972511518 1.5213878554963878 1.412245853945118 2.783738316091321 1.0 13.065258051918962 -4.581579390982537 1.3835361478878427 1.6758647581582127 17.17470940099944 0.9693337245222198 0.4560519976078193 0.28954324455591446 0.35390853331456573 0.1264268814993428 7.150706038599907 2.6207199154684448e-05 4.581579390982537 15.498844642841227 KVEVVS(ph)PATPVPSETAPASVFPQNGAAR ddPTM_PC-9_AZD4547_30min_R2 1 KVEVVSPATPVPSETAPASVFPQNGAAR 28 1 E9PRM3;E9PRL6;Q92993-2;Q92993-4;Q92993;Q92993-3 E9PRM3 KAT5 Histone acetyltransferase KAT5 1 KVEVVS(0.976)PAT(0.024)PVPSETAPASVFPQNGAAR 67.61 0.00010673 5880100.0 19537.0 17744.0 23671.0 26390.0 26500.0 26024.0 25575.0 31661.0 24565.0 28454.0 True False 25749.35960515533 23479.400997167977 23357.107073643358 20306.193221435617 22820.93242329643 24396.71516604859 27851.125454660076 26768.519947401444 25863.455749558558 27457.834120723546 0.9377782490761439 0.8551075403084002 0.8506536593873147 0.7395409678766216 0.831126458225361 0.8885156439791948 1.014323465288899 0.9748955372702959 0.9419335711565958 1.0 14.74493020945811 -7.0657369174410025 3.8551988833973896 0.9800128193229389 0.8391875052013895 0.6506477049430492 0.04831642948074972 0.15770187857977522 4.58452604744589 0.020435273539999892 0.015991274570722896 8.595340437503703e-08 7.0657369174410025 -0.14082531412154942 KVEVVS(ph)PATPVPSETAPASVFPQNGAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KVEVVSPATPVPSETAPASVFPQNGAAR 28 1 E9PRM3;E9PRL6;Q92993-2;Q92993-4;Q92993;Q92993-3 E9PRM3 KAT5 Histone acetyltransferase KAT5 1 KVEVVS(0.924)PAT(0.076)PVPSETAPASVFPQNGAAR;KVEVVS(0.915)PAT(0.085)PVPSETAPASVFPQNGAAR 86.009 1.9245e-07 11681500.0 56179.0 65669.0 64554.0 72206.0 87592.0 85545.0 76087.0 67371.0 72991.0 50293.0 True False 65688.99511417234 72188.18432869829 66093.2121824083 68160.53191501049 70428.9763844331 81058.86960663428 68879.48853782356 65602.58263547492 74058.35528959444 59410.72278083108 1.1056757440319671 1.215069956226654 1.112479516975904 1.1472765979713437 1.185459006183932 1.364381138833544 1.159378060285905 1.1042212510607874 1.246548633363697 1.0 15.858435719777782 -10.680582688049052 4.007129661073379 0.9999240136096185 1.1826392718116838 0.3442366638226564 0.07547249659149889 10289967.919914665 9170942.19071299 5939.83900688823 0.018695541961214136 2.0864948252631867e-11 10.680582688049052 0.18271525820206536 KVEVVS(ph)PATPVPSETAPASVFPQNGAAR ddPTM_PC-9_Lapatinib_30min_R1 3 KVEVVSPATPVPSETAPASVFPQNGAAR 28 1 E9PRM3;E9PRL6;Q92993-2;Q92993-4;Q92993;Q92993-3 E9PRM3 KAT5 Histone acetyltransferase KAT5 1 KVEVVS(0.977)PAT(0.023)PVPSETAPASVFPQNGAAR;KVEVVS(0.852)PAT(0.146)PVPS(0.001)ETAPASVFPQNGAAR;KVEVVS(0.843)PAT(0.157)PVPSETAPASVFPQNGAAR 73.175 2.7176999999999997e-05 10079800.0 30483.7 26892.299999999996 29887.1 27260.1 35174.4 27866.800000000003 22994.5 22556.9 28101.800000000003 23892.0 True False 30048.99684797409 26830.03253160799 27429.8980055423 29264.8986910278 33105.51094753114 26675.001924683595 24185.042697047385 23604.97592201201 24936.679358927042 28021.700365911114 1.072347375626399 0.9574733931652196 0.9788805692502247 1.0443655562968284 1.1814240576137403 0.9519408735500647 0.8630826245815157 0.8423819973012014 0.889906002608712 1.0 14.774256881179651 -6.994036737154709 24.97372675544833 0.888822654374751 1.0408778774340661 0.5112814992425169 0.06836413956790756 127.33047520192201 533247.4972898122 0.025108210823661232 0.022082834859624454 1.0138256221692976e-07 6.994036737154709 0.15205522305931507 KVGDDIAK ddPTM_PC-9_AZD4547_30min_R2 2 KVGDDIAK 8 1 P30050 P30050 RPL12 60S ribosomal protein L12 0 ; 78.939 0.013553 23380000.0 169325.0 161157.0 196175.0 267580.0 208566.0 191001.0 195058.0 239360.0 197718.0 232480.0 False True 223166.82782120715 213247.84865309985 193573.5913215322 205893.56506978933 179610.2110112168 179057.67727599357 212417.78412258383 202372.41194561103 208168.96983070273 224340.945961405 0.9947663671686583 0.9505525072083204 0.862854484686153 0.9177707804852115 0.8006127024271193 0.7981497827275729 0.9468524937000471 0.9020752367712073 0.9279133995740374 1.0 17.77533343478197 -10.290437104475014 19.415834135191336 0.9999999999999958 0.8965738603603122 0.19485910108444637 0.06047973557173897 0.0 0.0 0.06270640260924217 0.015208536550612491 5.123454639395447e-11 10.290437104475014 -0.10342613963968361 KVGDDIAK ddPTM_PC-9_Lapatinib_30min_R1 2 KVGDDIAK 8 1 P30050 P30050 RPL12 60S ribosomal protein L12 0 ; 90.15 0.006132100000000001 38513000.0 184760.0 155186.0 157608.0 149019.0 186893.0 139151.0 146596.0 143548.0 156371.0 143731.0 False True 182125.2885191656 154826.67635159957 144650.07862447354 159978.35437281142 175900.32118577533 133199.83610682422 154186.02358026296 150217.76412773822 138758.85132037048 168574.71184048138 1.0803832112820506 0.9184454457090143 0.8580769739731353 0.9490056523080134 1.043456158194273 0.7901531294496197 0.914645037187819 0.8911049735021114 0.8231296960582972 1.0 17.363028605979927 -6.7592994664494155 24.997318952043372 0.8789280419725037 0.9596461189627419 0.22720208283700272 0.0779778466769684 95.65615453846459 1117406.7123489685 0.026335003417615185 0.02511524361730018 1.740606229716044e-07 6.7592994664494155 0.08071807699023814 KVIYSQPS(ph)AR ddPTM_PC-9_AZD4547_30min_R2 2 KVIYSQPSAR 10 1 A0A087WY82;Q9Y624-2;Q9Y624 A0A087WY82 F11R Junctional adhesion molecule A 1 KVIYSQPS(1)AR;KVIYS(0.001)QPS(0.999)AR 59.79600000000001 0.03255 35020000.0 48825.0 98399.0 91002.0 93212.0 149604.0 74625.0 99660.0 144819.0 90267.0 72459.0 True False 64350.33437691095 130204.55245267892 89795.25402034956 71723.41351104419 128834.06695301305 69958.68695305775 108529.54693299829 122440.55115955706 95038.32933626714 69922.23246480309 0.920312926354334 1.862133800121732 1.2842160619735645 1.025759776007549 1.8425336607761278 1.000521357613589 1.5521464791277801 1.7510961370003486 1.3592004429221678 1.0 16.09346362723813 -4.711006422075602 23.62178689275864 1.4215341946408733 0.9202949741531968 0.17123994029716194 0.3211481455963792 15801.86641402588 7399955.345007797 0.07614016344719846 73.31272621476535 1.9453313150652515e-05 4.711006422075602 -0.5012392204876764 KVIYSQPS(ph)AR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KVIYSQPSAR 10 1 A0A087WY82;Q9Y624-2;Q9Y624 A0A087WY82 F11R Junctional adhesion molecule A 1 KVIYS(0.001)QPS(0.999)AR 54.871 0.042372 14081000.0 88618.0 42172.0 50490.0 49823.0 124750.0 55558.0 25890.0 61132.0 33763.0 21693.0 True False 103619.27711471793 46358.55745496151 51693.873084391285 47031.5788383454 100306.13302536802 52644.4406757307 23437.511772631995 59527.349774708055 34256.72000167941 25625.769178306484 4.043557732598205 1.8090601352253803 2.0172613249069915 1.8353235959902432 3.9142681855685435 2.054355532098404 0.9146071522595716 2.322948800502776 1.3368074832532038 1.0 14.645307688482617 -1.522878745872191 0.08863767796658427 0.06366321871644016 8.120848068441083 0.33165598149948705 0.8366652896347966 219.69855171464212 1.4083996606227553 17.085322702524113 215.3334778278652 0.02999999995911621 1.522878745872191 8.057184849724642 KVIYSQPS(ph)AR ddPTM_PC-9_Lapatinib_30min_R1 2 KVIYSQPSAR 10 1 A0A087WY82;Q9Y624-2;Q9Y624 A0A087WY82 F11R Junctional adhesion molecule A 1 KVIYS(0.001)QPS(0.999)AR;KVIYSQPS(1)AR 62.528 0.0271 19865400.0 327860.0 206751.0 102908.0 55543.0 69996.0 29341.0 28509.0 35908.0 118813.0 31973.0 True False 323184.6562778391 206272.28076224323 94447.30147636781 59627.81750601636 65878.97289743081 28086.15382721165 29985.056524391668 37576.41676859881 105431.02878364388 37499.49044865545 8.618374607525551 5.500668896946015 2.51862892925667 1.5900967397852823 1.7567964820117419 0.7489742791483366 0.7996123724786982 1.0020513964062707 2.811532304098925 1.0 15.194583371632838 -4.908310999004395 1.2536861749037622 1.283682683649767 10.978028758036977 0.9444937277392359 0.5683038557608764 0.23961947037518438 0.3840904811223664 0.17591121676996474 2.8450076969438167 1.2350626862438723e-05 4.908310999004395 9.69434607438721 KVLMEMGPPYAGQQELASFHS(ph)TSK ddPTM_PC-9_Lapatinib_30min_R1 1 KVLMEMGPPYAGQQELASFHSTSK 24 1 P24298 P24298 GPT Alanine aminotransferase 1 1 KVLMEMGPPY(0.019)AGQQELAS(0.087)FHS(0.298)T(0.298)S(0.298)K 46.953 0.035533999999999996 0.0 7895.8 1212.4 5919.7 2073.0 6127.8 2657.7 4819.7 2387.9 6373.8 2265.5 True False 7783.204444087618 1209.5927622896338 5433.005116702811 2225.455335325279 5767.374851718333 2544.036366401293 5069.240483026784 2498.8505514575345 5655.915524910481 2657.0886564110024 2.9292227134794184 0.455232368468827 2.0447210534710987 0.8375540386865595 2.1705616927018436 0.9574525713558945 1.9078175923094478 0.9404468102441098 2.128613778566979 1.0 11.375630650251383 -1.5229063306178234 0.03425067461717188 7.447956285758837e-08 3.7982619579869494 0.05230328945364304 0.7365548727789254 4404.575602446328 11.579276065335334 384.2600591695504 1052.9512564959057 0.02999809453290957 1.5229063306178234 3.7982618835073865 KVPCS(ph)PDFQR ddPTM_PC-9_AZD4547_30min_R2 1 KVPCSPDFQR 10 1 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 KVPCS(1)PDFQR 53.946999999999996 0.044325 7134300.0 26243.0 24996.0 41165.0 61751.0 46268.0 54892.0 50303.0 55494.0 41254.0 47847.0 True False 34587.728111690216 33075.46817657861 40619.125203266834 47515.26099343961 39844.48684381435 51459.59456250917 54779.86955017659 46918.67742525808 43434.602218289794 46171.891093493374 0.7491078942738904 0.7163550678399582 0.8797370920116148 1.0290949724633554 0.8629598203619888 1.1145221333540083 1.1864333093754582 1.0161740468947338 0.9407152531469667 1.0 15.494727202587198 -5.523212610372714 1.1429559900405806 1.0419751037101634 0.693364936568461 0.6457495208243749 0.08493658476248091 0.41056772561399235 0.9283876407890278 0.031246646388543 0.12677707482687334 2.9976946278898185e-06 5.523212610372714 -0.34861016714170245 KVPCS(ph)PDFQR ddPTM_PC-9_Lapatinib_30min_R1 1 KVPCSPDFQR 10 1 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 KVPCS(1)PDFQR 62.298 0.027558999999999997 31810000.0 56940.0 57123.0 61564.0 53589.0 53208.0 54079.0 49575.0 58014.0 61620.0 46598.0 True False 56128.02515848285 56990.73520312667 56502.4455639124 57530.11382766346 50078.41005095286 51766.16723430618 52141.75092766202 60709.54223051942 54679.70671263357 54652.40221206792 1.027000147965849 1.042785548236019 1.0338510893750974 1.0526548056282896 0.9163075733914388 0.9471892385157696 0.9540614651362659 1.1108302613112586 1.0004996029352873 1.0 15.737997289596144 KVPPPS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 KVPPPSPK 8 1 A0A075B754;Q96QE3 A0A075B754 ATAD5 ATPase family AAA domain-containing protein 5 1 KVPPPS(1)PK 56.551 0.039 11700000.0 74622.0 97332.0 65199.0 88420.0 77356.0 71418.0 69813.0 74777.0 65638.0 77533.0 True False 98350.24376597744 128792.66556900112 64334.41865973021 68036.13507538219 66616.45466175546 66952.22117002978 76026.22175429839 63221.93285451617 69107.49067736712 74818.59326920865 1.314516077736163 1.7213991862368432 0.8598720698776735 0.9093479588767174 0.8903729908695202 0.8948607324001071 1.016140753685979 0.845002961055871 0.9236673353200839 1.0 16.19110922030299 -5.27024200547481 24.997116283093174 0.9133399753831806 1.5179576379690616 0.8406301304341925 0.1045826401427413 178.72710205091212 507538.1690663831 0.02492007328039554 0.05315162180520135 5.36732625101959e-06 5.27024200547481 0.604617662585881 KVPPPS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 KVPPPSPK 8 1 A0A075B754;Q96QE3 A0A075B754 ATAD5 ATPase family AAA domain-containing protein 5 1 KVPPPS(1)PK 60.255 0.032329000000000004 9679000.0 81818.0 90517.0 60892.0 52222.0 55149.0 61764.0 81898.0 62281.0 64128.0 41060.0 True False 80651.26031641637 90307.4134478477 55885.694809917324 56062.580087485156 51905.24424710568 59122.497698916224 86138.27771000846 65174.80262796881 56905.2293422227 48157.166290989066 1.6747509566713739 1.875264273279003 1.1604855333934876 1.1641586165748983 1.0778301184390482 1.2276988505027326 1.7886907462436434 1.353377028751046 1.18165651604942 1.0 15.555462881733957 -5.261017624536798 24.99609771124327 1.2669088369576311 1.7750076433546411 0.5051572360860963 0.2091688224861468 31.916095651287574 1891410.2702722868 0.05805075637518259 0.13580847151663544 5.482547151988918e-06 5.261017624536798 0.50809880639701 KVQAEDEANGLQT(ph)TPASR ddPTM_PC-9_Lapatinib_30min_R1 1 KVQAEDEANGLQTTPASR 18 1 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 KVQAEDEANGLQT(0.492)T(0.492)PAS(0.017)R 61.815 0.019049 6263400.0 33462.0 34313.0 36640.0 35042.0 37323.0 35290.0 33237.0 34217.0 31083.0 19393.0 True False 32984.825743820744 34233.55035668443 33627.60063449013 37619.10557668519 35127.734519841266 33780.72896500798 34957.84923010999 35806.84673529982 27582.105221499336 22745.05421045179 1.4501977194085376 1.5050986486967108 1.478457704402287 1.6539466219165346 1.5444119936939695 1.4851900836308 1.5369428846666007 1.5742695710457302 1.212663859417175 1.0 14.473265252695471 -8.45357500957553 3.1460765491641105 1.0031173493050312 1.5296371497256547 0.9067895872990419 0.0560526789337327 0.06280535037598019 1.2755594901918765 0.05610697628103857 0.014970269515898488 3.519046377387304e-09 8.45357500957553 0.5265198004206235 KVQAEDEANGLQTTPAS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 KVQAEDEANGLQTTPASR 18 1 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 KVQAEDEANGLQTT(0.001)PAS(0.999)R 147.02 6.272399999999999e-05 40733000.0 92566.0 74483.0 148780.0 163610.0 122110.0 140990.0 151800.0 121960.0 110650.0 113600.0 True False 122000.06250759149 98558.17315554916 146807.0799888748 125892.24224930191 105157.13427202763 132173.8730118812 165309.90592443416 103113.8843619935 116498.73310354787 109622.89857714919 1.1129067383830544 0.8990655641730453 1.3392008594404803 1.148411909220799 0.9592624865508488 1.2057140864493867 1.507986999706035 0.9406235895999882 1.0627226119327586 1.0 16.742189661541175 KVQAEDEANGLQTTPAS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 KVQAEDEANGLQTTPASR 18 1 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 KVQAEDEANGLQT(0.031)T(0.273)PAS(0.696)R;KVQAEDEANGLQT(0.001)T(0.001)PAS(0.997)R;KVQAEDEANGLQT(0.001)T(0.007)PAS(0.992)R;KVQAEDEANGLQT(0.007)T(0.061)PAS(0.932)R 179.19 5.4081999999999996e-09 68521500.0 171022.0 157543.0 158928.0 153628.0 149571.0 151700.0 155930.0 138728.0 144780.0 103848.0 True False 199972.64676152956 173182.82787458494 162717.44625779663 145020.72122869632 120263.63625440745 143744.58494741263 141159.1815645621 135086.5369944658 146897.13360314982 122674.82033968445 1.630103441014291 1.4117226941522694 1.3264127537112738 1.1821555623813955 0.980344914477148 1.1717529689416815 1.150677711805037 1.1011757475610198 1.1974513856746984 1.0 16.904479632981847 -5.147934737556044 1.0875145112715099 1.108294892996089 1.7029756758362775 0.8490428909314259 0.07217304721259966 0.3763740069812278 0.5522145641407946 0.024121009574314723 0.22370918609634818 7.11320397396203e-06 5.147934737556044 0.5946807828401885 KVQAEDEANGLQTTPAS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 KVQAEDEANGLQTTPASR 18 1 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 KVQAEDEANGLQT(0.001)T(0.001)PAS(0.998)R 87.729 0.00073943 42161000.0 78050.0 59881.0 56023.0 56156.0 53184.0 44947.0 42914.0 36160.0 60911.0 30613.0 True False 76936.9926873828 59742.34922357769 51417.00519503381 60285.89957092444 50055.82168376707 43024.721586574466 45135.876940185335 37840.12560857004 54050.561758734504 35904.416260741564 2.1428281169831154 1.6639276012656103 1.4320523921524926 1.6790664171538687 1.394141080591773 1.1983128001336802 1.2571121227094726 1.0539128483184674 1.5054014906192532 1.0 15.131873686706898 -1.5228787452803403 0.33206464239884886 1.150025073965797 10.792167531810671 0.7540007615232909 0.1600800141630648 28.93772840008479 0.41162016171577454 0.14296578948381575 171.60248717513647 0.02999999999999981 1.5228787452803403 9.642142457844875 up KVQVAALQAS(ph)PPLDQDDR ddPTM_PC-9_AZD4547_30min_R2 11 KVQVAALQASPPLDQDDR 18 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IU26;B1AN86;U3KQJ2 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR 113.07 0.00010451 254919200.0 916160.1 836683.0 1127133.0 1351535.0 1204902.0 1208936.5 1004031.0 1277793.0 982261.8 1133944.0 True False 1207479.9544861044 1107124.4175221764 1112186.4799643802 1039959.4867575981 1037622.1554224413 1133341.5095427174 1093387.8139342244 1080339.452612046 1034182.1534207903 1094244.9657056911 1.103482302710332 1.0117701723289896 1.016396250219089 0.9503900126119532 0.9482539905982267 1.0357292425940587 0.9992166728672918 0.9872921388450918 0.945110268571201 1.0 20.061504315907356 -4.397883560647381 1.3472249388962367 0.983524887316391 1.2796818998506787 0.6163659401434044 0.028184106115406816 2.262109938232064 1.8443227972376877 0.008535513450446033 1.1771367000048114 4.000519939309594e-05 4.397883560647381 0.2961570125342877 KVQVAALQAS(ph)PPLDQDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 KVQVAALQASPPLDQDDR 18 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IU26;B1AN86;U3KQJ2 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR 122.87 2.4421999999999998e-05 76939900.0 623630.0 629261.0 717607.0 707501.0 803027.0 688918.0 769314.0 708100.0 646962.0 562337.0 True False 729198.2417460483 691729.8734389278 734717.4724197021 667862.0127191887 645679.6239275525 652789.9273091736 696439.0085689707 689513.1252939677 656422.5953181444 664284.2466427577 1.0977202085272397 1.0413160886094743 1.1060287461774212 1.0053858963154896 0.9719929791964336 0.9826966853546875 1.0484051248975432 1.0379790410185321 0.9881652299232664 1.0 19.341441176058233 -5.775645211297723 24.973163232757862 1.0060395141145801 1.0776511176490375 0.6244441911957848 0.02720977818891586 159.9085061345922 281111.3256935362 0.008099745129642918 0.012078004558185732 1.6763117481426247e-06 5.775645211297723 0.07161160353445739 KVQVAALQAS(ph)PPLDQDDR ddPTM_PC-9_Lapatinib_30min_R1 4 KVQVAALQASPPLDQDDR 18 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IU26;B1AN86;U3KQJ2 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR 141.5 4.1592e-05 190902000.0 872903.0 912520.0 937944.0 863241.0 1022626.0 874134.0 803447.0 829256.0 982949.0 757146.0 True False 860455.2431491935 910407.1160050624 860829.8648885438 926726.6228275566 962477.1492400706 836749.326525879 845045.5543636358 867786.2611078651 872238.9327081544 888017.6772663719 0.9689618407124223 1.025212830005381 0.9693837036425653 1.0435902871667424 1.0838490875574807 0.9422665200783898 0.9516089330169426 0.9772173272262032 0.9822314972301115 1.0 19.760228870213425 -6.80249935027201 24.99998470910916 0.9680499502179716 1.0172881247127816 0.3175726440106704 0.03472220446030578 188.375587994775 114694.11606349483 0.012669927673387767 0.01117391997916312 1.5757983802216072e-07 6.80249935027201 0.04923817449481005 KVS(ph)GTLDTPEK ddPTM_PC-9_AZD4547_30min_R2 1 KVSGTLDTPEK 11 1 H7BZL0;Q9BYG3;C9J808 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 KVS(0.508)GT(0.009)LDT(0.483)PEK 96.70700000000001 0.008179800000000001 0.0 37198.0 52964.0 44469.0 29244.0 36602.0 41491.0 47469.0 43415.0 43878.0 45377.0 True False 49026.19023353473 70083.57723252963 43879.31200447156 22502.247615296073 31520.444096509298 38896.56121097919 51693.64904036205 36706.209327451215 46197.30150128759 43788.36504168387 1.1196168248543825 1.600506827916829 1.0020769663973779 0.5138864534877083 0.7198360584256512 0.8882853053305831 1.1805338927624456 0.8382639838804012 1.055013162910069 1.0 15.418259963382276 -5.452550198301141 6.944213567113227 0.8745750449708615 1.3515176166821985 0.45820116855370907 0.20336115906878371 0.21986298385189623 18.417133867187026 0.05523690528503159 0.1152848114254796 3.5273601296711347e-06 5.452550198301141 0.476942571711337 KVS(ph)GTLDTPEK ddPTM_PC-9_Lapatinib_30min_R1 1 KVSGTLDTPEK 11 1 H7BZL0;Q9BYG3;C9J808 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 KVS(0.816)GT(0.014)LDT(0.17)PEK 74.133 0.010624 19769000.0 27190.0 38051.0 33490.0 29920.0 39334.0 32015.0 35390.0 35695.0 28094.0 29412.0 True False 26802.265613964668 37962.89524734646 30736.581475138482 32120.416610194086 37020.451453619375 30645.793080610078 37222.32103540009 37353.52001100411 24929.75787706471 34495.82501097345 0.7769712887121445 1.1005069522259607 0.8910232315174629 0.9311392494592107 1.0731864346436943 0.8883913653568616 1.079038435044221 1.0828417641590424 0.7226891332250878 1.0 15.074134144325988 -4.7358711301168075 24.655374431850653 0.9766271815051651 0.7769701603984391 0.2138725388497139 0.11342533802695001 3278.633630008384 3161378.979334301 0.026759241313514478 1.945960178889519 1.837083387344507e-05 4.7358711301168075 -0.199657021106726 KVS(ph)IIETK ddPTM_PC-9_Lapatinib_30min_R1 1 KVSIIETK 8 1 H7C1A0;Q9HC62-2;Q9HC62 H7C1A0 SENP2 Sentrin-specific protease 2 1 KVS(1)IIETK 59.11600000000001 0.03438 9507300.0 83761.0 82642.0 74631.0 70111.0 66752.0 61741.0 66776.0 70975.0 72467.0 79063.0 True False 82566.55278011393 82450.64752650916 68495.12726399102 75267.19682343965 62825.77859948132 59100.48135530055 70233.33454252269 74272.75760697629 64305.003348659724 92728.93420517471 0.8904076541786278 0.8891577179575523 0.7386597058522933 0.8116905199934821 0.6775207667163649 0.6373467123490617 0.7574047425922354 0.8009663676564884 0.6934729046532189 1.0 16.50073195271601 -5.257729077357756 22.468674354877706 0.7512897888137733 0.8897827646111534 0.20810898150984647 0.09483573258706504 100.41463064495551 608053.062005356 0.023273240635366583 0.0565804336848383 5.524219450185873e-06 5.257729077357756 0.13849297579738007 KVS(ph)IVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KVSIVSK 7 1 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 KVS(1)IVSK 57.174 0.040451 4649700.0 68018.0 100100.0 61510.0 43292.0 48854.0 40661.0 46499.0 37888.0 29585.0 30824.0 True False 79532.1039832638 110037.26646214684 62976.631677973994 40866.48959455771 39281.409401373385 38528.665580400426 42094.278096393005 36893.480145654285 30017.624655678886 36412.14719735027 2.1842190067014613 3.0219933437529964 1.7295500684605831 1.1223312202124565 1.0787995881833607 1.0581267117146054 1.1560504209830347 1.013219021270436 0.8243849090520892 1.0 15.152132197498348 -5.528911638290959 3.048122346476013 1.0439806451072804 2.5987939375118922 0.8942474525824378 0.21444452090045965 0.06622707900436219 1.2522347272132275 0.0563911438310338 0.11984597158703482 2.9586143660444813e-06 5.528911638290959 1.5548132924046119 up KVS(ph)KQEEASGGPTAPK ddPTM_PC-9_Lapatinib_30min_R1 1 KVSKQEEASGGPTAPK 16 2 K7EM16;P50552 K7EM16 VASP Vasodilator-stimulated phosphoprotein 1 KVS(0.867)KQEEAS(0.131)GGPT(0.003)APK 43.163999999999994 0.044631 10698000.0 130810.0 112970.0 113970.0 127700.0 116670.0 96069.0 81588.0 70222.0 92046.0 113990.0 True False 128944.62541238402 112708.42490585583 104599.82653692267 137091.48399471174 109807.69998204532 91960.35281777712 85812.22742684998 73484.77047801438 81678.81019264963 133693.01961787263 0.9644828561800707 0.8430389651457054 0.7823880920327372 1.0254199088819502 0.8213420588143091 0.6878470774362215 0.6418601933902183 0.5496530087214115 0.6109429678984561 1.0 17.028564615817395 -6.688167704213045 3.4494569232586834 0.664028324111586 0.8938223587768704 0.3458175824945895 0.12939938709536053 0.23606783424200148 5.608244499469051 0.04388917980533017 0.042693306659202755 2.0503702688525727e-07 6.688167704213045 0.22979403466528447 KVS(ph)LVLEK ddPTM_PC-9_AZD4547_30min_R2 1 KVSLVLEK 8 1 Q9P2M7-2;Q9P2M7;H0Y4A8 Q9P2M7-2 CGN Cingulin 1 KVS(1)LVLEK 54.772 0.042203 24057000.0 86602.0 67131.0 96048.0 106500.0 101880.0 95105.0 86278.0 88727.0 99534.0 91700.0 True False 114139.63456649764 88829.78293174504 94774.34076335165 81948.07040859765 87735.72057680927 89158.06931551828 93956.57485736693 75016.2808936258 104795.16403731161 88489.61091130761 1.2898648032354763 1.0038442029175423 1.0710222339924533 0.9260756100592815 0.9914804650316074 1.0075540890882735 1.0617808564164533 0.8477411090530613 1.1842651691885833 1.0 16.433220465631543 -4.761194942846966 24.999999955363883 1.0058420305092666 1.2898651180531575 0.49742595442418625 0.08415362044602256 4.504242761721395 459758.2970630462 0.019231417835951968 0.10857894869591012 1.733025915473512e-05 4.761194942846966 0.28402308754389094 KVS(ph)LVLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KVSLVLEK 8 1 Q9P2M7-2;Q9P2M7;H0Y4A8 Q9P2M7-2 CGN Cingulin 1 KVS(1)LVLEK 58.674 0.035176 22951000.0 78677.0 83655.0 87362.0 94498.0 92646.0 81593.0 80293.0 91363.0 81289.0 62582.0 True False 91995.46215841734 91959.7155433652 89445.04140223018 89203.58342664945 74492.68136487578 77314.11944373258 72687.06576902037 88964.81805710024 82477.69784132097 73927.62120116058 1.244399057668761 1.2439155223612353 1.2099001692323625 1.2066340290312094 1.0076434241293608 1.0458082944851854 0.9832193243609908 1.2034043110223003 1.1156546971380998 1.0 16.173825871454387 -6.159074342637373 5.491307596035994 1.0653270630224458 1.2294289616601173 0.6419432009545143 0.06110004523449588 0.16434901890451453 7.228258018919554 0.019426831118599237 0.02528700364108437 6.933071153737538e-07 6.159074342637373 0.16410189863767144 KVS(ph)LVLEK ddPTM_PC-9_Lapatinib_30min_R1 2 KVSLVLEK 8 1 Q9P2M7-2;Q9P2M7;H0Y4A8 Q9P2M7-2 CGN Cingulin 1 KVS(1)LVLEK;KVS(1)LVLEK 54.65 0.042422 41596000.0 183118.0 174482.0 208940.0 171495.0 172785.0 153150.0 157564.0 161974.0 188568.0 163138.0 True False 180506.7037402712 174077.9976491421 191761.75973172404 184107.31439054958 162622.12600838006 146600.1315100869 165721.8929534271 169499.90335515872 167329.48613092964 191336.18593227866 0.9434007626981733 0.9098017544405066 1.0022242201461882 0.962219004698423 0.8499287534974611 0.766191354739215 0.8661293844964723 0.8858747890749288 0.8745313141663338 1.0 17.545750219674147 -6.259626500991858 24.93267908284223 0.8623081141310952 0.9546402323492953 0.30646243257791406 0.05790390478494809 174.44897211423705 2399213.37877855 0.01742404757411232 0.021348644890004875 5.500136895744257e-07 6.259626500991858 0.09233211821820009 KVS(ph)PASGVSK ddPTM_PC-9_Lapatinib_30min_R1 1 KVSPASGVSK 10 1 Q9UNY4-2;Q9UNY4 Q9UNY4-2 TTF2 Transcription termination factor 2 1 KVS(0.981)PAS(0.019)GVSK 77.279 0.032296 3865500.0 33666.0 22089.0 23272.0 20377.0 24909.0 22359.0 22920.0 24782.0 24100.0 18459.0 True False 33185.91666641172 22037.854277644117 21358.665992517857 21875.59255567932 23443.901592978225 21402.757691374696 24106.685451578698 25933.462191138915 21385.60421574924 21649.613554928572 1.5328641586240643 1.017932916988588 0.9865610736342922 1.010438015448978 1.0828785249906312 0.9885976780635108 1.1134926445876798 1.1978718292288002 0.9878053555778492 1.0 14.402053652660157 -4.759280662100857 24.999763104225302 1.0480179103927145 1.5328647806406395 0.8322375238231299 0.06596571977524235 23.229714135656025 268955.15089142596 0.017158104346961734 0.11040625407493888 1.7406815971826435e-05 4.759280662100857 0.48484687024792494 KVS(ph)VSESNVLLDEEVLTDPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KVSVSESNVLLDEEVLTDPK 20 1 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 KVS(0.333)VS(0.333)ES(0.333)NVLLDEEVLTDPK;KVS(0.474)VS(0.474)ES(0.053)NVLLDEEVLTDPK 104.38 7.2837e-05 9564800.0 111876.0 143670.0 105195.0 144712.0 149951.0 109864.0 150710.0 142918.0 115881.0 109265.0 True False 130814.39714827869 157932.60811804814 107703.24775425933 136604.25580263385 120569.17798226005 104102.53843548155 136433.65775408907 139166.55393413827 117575.54039968662 129073.87955873592 1.0134846616177733 1.2235830259226064 0.8344310105380249 1.0583415968408325 0.9341098167533909 0.806534511795696 1.0570198883036133 1.0781930039594851 0.9109166068428516 1.0 16.97783754910342 -5.256061459338763 24.999288253473864 0.9633156474587503 1.1185338325702248 0.288097488043216 0.09960615520050733 560.4357519388996 2605165.6164196744 0.025228962433566253 0.06281606585344945 5.545472304553656e-06 5.256061459338763 0.15521818511147445 KVS(ph)VSESNVLLDEEVLTDPK ddPTM_PC-9_Lapatinib_30min_R1 1 KVSVSESNVLLDEEVLTDPK 20 1 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 KVS(0.431)VS(0.431)ES(0.139)NVLLDEEVLTDPK 122.97 3.4867e-06 6448700.0 30069.0 73501.0 58745.0 58800.0 86029.0 76519.0 87117.0 102020.0 92922.0 81864.0 True False 29640.210546020724 73330.81295038782 53915.21286225768 63124.34815104986 80968.94335952161 73246.46074450115 91627.49199324535 106760.22164232089 82456.14584796054 96014.08332307648 0.308706905488904 0.7637505917089055 0.5615344228287752 0.6574488446517122 0.8433027797294103 0.7628720517805199 0.9543130426494751 1.1119225216480468 0.858792199999504 1.0 16.55095841507255 -5.426661995230576 0.3679482010930233 1.0379605593480956 0.19749568516018312 0.7175960818828967 0.11697720360453623 2.1119794409597286 0.3246504206378943 0.11229467297548877 0.7550775703350467 3.7440186616913207e-06 5.426661995230576 -0.8404648741879125 down KVS(ph)YSHIQSK ddPTM_PC-9_AZD4547_30min_R2 1 KVSYSHIQSK 10 1 E7EVA0;P27816-4;H0Y2V1;F8W9U4;P27816;P27816-6;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 KVS(0.653)Y(0.027)S(0.32)HIQSK 49.483000000000004 0.044402 16782000.0 119750.0 132810.0 179960.0 250910.0 246750.0 197200.0 156570.0 235390.0 182080.0 201690.0 True False 157828.00904526585 175738.2352588977 177573.61281622472 193066.5760208569 212493.0217150335 184869.05282603696 170504.42668371985 199015.88422408668 191704.37707631258 194628.89448965786 0.8109176669739162 0.902940109276714 0.912370248425064 0.9919728338749622 1.0917855864732608 0.9498540970023364 0.8760488884798144 1.022540279776711 0.984973878513703 1.0 17.57036638210183 -5.066661235439885 1.3545238483005861 0.985325214487216 0.7942658901189507 0.5131932318698644 0.053640232043051794 0.7242487043385263 1.7041351259308333 0.017436608350647264 0.16525106670033357 8.577066248843592e-06 5.066661235439885 -0.19105932436826534 KVSGTLDT(ph)PEKTVDSQGPTPVCTPTFLER ddPTM_PC-9_AZD4547_30min_R2 1 KVSGTLDTPEKTVDSQGPTPVCTPTFLER 29 2 H7BZL0;Q9BYG3;C9J808 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 KVS(0.044)GT(0.044)LDT(0.804)PEKT(0.088)VDS(0.017)QGPT(0.002)PVCTPTFLER 54.675 0.001227 14956000.0 7795.4 7847.3 12314.0 21523.0 12698.0 8886.5 10262.0 13101.0 9431.7 13308.0 True False 10274.175045607199 10383.786262684642 12150.708314175334 16561.20487703519 10935.101883434647 8330.82575019562 11175.298119871826 11076.541481030486 9930.240406802823 12842.09097063994 0.800039111161601 0.8085744203513614 0.9461627660133174 1.2896034543672075 0.8515047828608969 0.6487125631831965 0.8702086089735078 0.8625185342756162 0.7732572857103803 1.0 13.64859250314463 -6.502545681778336 24.994924775086613 0.8165019413777558 0.9643115311199226 0.14328823077918373 0.1503597468731684 1453.9963642630887 1787363.3903266187 0.04944233451504553 0.05537563091735696 3.143795718998405e-07 6.502545681778336 0.14780958974216685 KVSGTLDT(ph)PEKTVDSQGPTPVCTPTFLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KVSGTLDTPEKTVDSQGPTPVCTPTFLER 29 2 H7BZL0;Q9BYG3;C9J808 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 KVS(0.038)GT(0.038)LDT(0.536)PEKT(0.374)VDS(0.014)QGPTPVCTPTFLER 43.622 0.017646000000000002 7127500.0 8432.7 4866.6 5283.9 9799.8 13239.0 12555.0 9206.3 14355.0 9785.0 9172.6 True False 9860.189556583082 5349.723885761064 5409.8882153023405 9250.74897738027 10644.912986956699 11896.593698185668 8334.212616159979 13978.196460379744 9928.087113598702 10835.519769738356 0.9099876855119406 0.4937210211827469 0.49927353096721566 0.8537429836283384 0.9824090780292805 1.0979255218942703 0.7691566988263845 1.2900346967589238 0.9162538876377717 1.0 13.403480739371288 -5.994129241419335 3.544117557500217 1.0132335855380794 0.6216072370629493 0.5067593539434991 0.16468335317295715 0.17780268240211505 4.801700129802997 0.04780827670342324 0.06987184337525669 1.0136097013819196e-06 5.994129241419335 -0.3916263484751301 KVSGTLDTPEKT(ph)VDSQGPTPVCTPTFLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KVSGTLDTPEKTVDSQGPTPVCTPTFLER 29 2 H7BZL0;Q9BYG3;C9J808 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 KVS(0.009)GT(0.008)LDT(0.141)PEKT(0.555)VDS(0.28)QGPT(0.007)PVCTPTFLER 46.403999999999996 0.011387999999999999 6992900.0 8765.3 5469.7 6073.3 11350.0 12780.0 14154.0 8294.2 15678.0 14100.0 10305.0 True False 10249.092167433644 6012.695668012016 6218.11050511851 10714.09629719648 10275.850741997627 13411.739323307038 7508.513331192131 15266.469112214107 14306.185825420727 12173.21492566489 0.8419379950176841 0.4939283258143582 0.5108026550988446 0.880136953353864 0.8441361468393174 1.1017417670849594 0.6168061089073413 1.2541033084060385 1.1752183718747031 1.0 13.571422611265417 -6.4905145767353885 0.7290720022555968 1.0878955868538571 0.5946937145995377 0.44360067995489594 0.18979003724862972 0.6624442505089689 0.7831120579482016 0.1257055912139289 0.1697873269796692 3.232104718651595e-07 6.4905145767353885 -0.49320187225431944 KVSS(ph)SSPQSGCPSPTIPAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KVSSSSPQSGCPSPTIPAGK 20 1 E7EWD6;Q76L83;A0A5F9ZHC8 E7EWD6 ASXL2 Putative Polycomb group protein ASXL2 1 KVS(0.061)S(0.312)S(0.312)S(0.312)PQS(0.002)GCPSPTIPAGK 82.639 0.006402199999999999 0.0 22095.0 21557.0 25429.0 30362.0 36221.0 28904.0 28098.0 25088.0 24464.0 21885.0 True False 25835.247103857993 23697.036494750188 26035.323800019538 28660.915574932114 29123.75506462411 27388.22335741603 25436.35402809632 24429.46658293324 24821.73971865905 25852.577258435314 0.9993296546644429 0.9166218229564789 1.00706879394489 1.1086289497725215 1.126531980679855 1.0594001164228088 0.9839001262358403 0.9449528508792007 0.9601263143139852 1.0 14.658020490365207 -10.068275402308672 7.130852179155175 1.0000034052793716 1.013729013838292 0.002234886843290096 0.0648004906689125 0.0 0.0 0.07222939914222341 0.01751820246695793 8.545246551180363e-11 10.068275402308672 0.013725608558920355 KVSS(ph)SSPQSGCPSPTIPAGK ddPTM_PC-9_Lapatinib_30min_R1 1 KVSSSSPQSGCPSPTIPAGK 20 1 E7EWD6;Q76L83;A0A5F9ZHC8 E7EWD6 ASXL2 Putative Polycomb group protein ASXL2 1 KVS(0.092)S(0.303)S(0.303)S(0.303)PQSGCPSPTIPAGK 100.39 0.0011172 0.0 50094.0 39658.0 43702.0 29399.0 36293.0 29117.0 24626.0 28544.0 35789.0 24263.0 True False 49379.650373885466 39566.17433758024 40108.99025459843 31561.10053218905 34158.317094783364 27871.73378504214 25901.013784056577 29870.25844499512 31758.065945122387 28456.82722158469 1.735247924492112 1.3903930339630077 1.4094681020579658 1.1090871194610814 1.2003557820695505 0.9794392596199638 0.9101862826229092 1.0496693188036907 1.116008671586328 1.0 14.796487197884302 -4.596360304319592 0.5702994068170557 1.001929493026934 2.316648548862497 0.8764556196790446 0.08436990790524171 1.54929468791239 0.32927565003084336 0.045659193381515986 1.4123343870264333 2.533026280504815e-05 4.596360304319592 1.314719055835563 KVSVS(ph)ESNVLLDEEVLTDPK ddPTM_PC-9_AZD4547_30min_R2 1 KVSVSESNVLLDEEVLTDPK 20 1 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 KVS(0.449)VS(0.506)ES(0.045)NVLLDEEVLTDPK 143.36 0.00011833 7462500.0 40724.0 48232.0 43526.0 41361.0 40348.0 41825.0 53810.0 44628.0 49861.0 45623.0 True False 53673.38488817861 63822.05077183306 42948.816800616834 31825.860471079894 34746.376657176035 39209.67613817945 58598.9857562174 37731.76804941826 52496.55066675101 44025.75265656046 1.219136111241031 1.4496526900903006 0.975538502104787 0.7228919109992181 0.7892284529063772 0.8906077414291895 1.3310161035369676 0.8570385688521714 1.192405524018413 1.0 15.426060047878629 -5.27551401479438 22.563521137514503 0.9595343189992522 1.3343943405446892 0.3975472545173224 0.17915084603693407 189.06180282591686 303092.9279952626 0.04877056490882048 0.10260069923995588 5.302564808404032e-06 5.27551401479438 0.37486002154543696 KVSVS(ph)ESNVLLDEEVLTDPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KVSVSESNVLLDEEVLTDPK 20 1 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 KVS(0.363)VS(0.632)ES(0.005)NVLLDEEVLTDPK 128.51 1.2567999999999999e-05 7246000.0 40782.0 57201.0 40243.0 54929.0 53028.0 38724.0 62433.0 47572.0 45134.0 43408.0 True False 47685.587118784206 62879.53725176067 41202.54574242739 51851.50621222076 42637.54406468313 36693.24527029404 56518.89426422304 46323.285406700474 45793.999364860894 51277.52678246107 0.929950996292874 1.2262591664867102 0.8035205347797757 1.0111935864651727 0.8315054711115054 0.7155814169033708 1.1022156841533692 0.9033837689407606 0.8930617804391502 1.0 15.646039059120664 -5.271022797192326 24.979637540153334 0.9051880972140753 1.0781050901048395 0.230958948196887 0.12442348742748688 820.00783632549 2137392.8530358667 0.031538291986553994 0.06704421064424007 5.3576853295874885e-06 5.271022797192326 0.17291699289076412 KVSVS(ph)ESNVLLDEEVLTDPK ddPTM_PC-9_Lapatinib_30min_R1 1 KVSVSESNVLLDEEVLTDPK 20 1 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 KVS(0.264)VS(0.439)ES(0.297)NVLLDEEVLTDPK 155.8 8.7773e-06 6416900.0 36702.0 89072.0 86154.0 87229.0 105630.0 95387.0 113540.0 107310.0 112480.0 92213.0 True False 36178.622749677495 88865.7592565675 79070.75068405732 93644.11164741367 99417.05107657016 91307.52036795735 119418.54564451339 112296.01435441493 99811.31793309013 108151.89418390105 0.33451677404890856 0.8216754771345984 0.7311083294538118 0.8658573421578876 0.9192354126273721 0.8442526231921412 1.1041743331971103 1.0383175921400623 0.9228809045486652 1.0 16.72269940747401 -4.585904851888904 0.640630090341268 0.9899508559181354 2.201960400320688e-20 0.775258329924415 0.09633590483519637 2.0663403674755347 0.5383158225290638 0.04455365751239233 1.5874591265358644 2.594747774376225e-05 4.585904851888904 -0.9899508559181354 down KVSVSES(ph)NVLLDEEVLTDPK ddPTM_PC-9_AZD4547_30min_R2 1 KVSVSESNVLLDEEVLTDPK 20 1 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 KVS(0.18)VS(0.18)ES(0.641)NVLLDEEVLTDPK 99.273 0.00016768 8927500.0 65659.0 84053.0 77050.0 74087.0 68809.0 72139.0 81980.0 77739.0 82026.0 80414.0 True False 86537.19620795881 111221.48850399912 76028.26665642431 57007.38678273976 59256.05807979645 67628.13692605213 89276.06118369634 65726.22381450489 86361.72690060199 77598.73033611666 1.1151883005446797 1.43329005542032 0.9797617348519759 0.7346432929484016 0.7636214899796756 0.87151086922586 1.1504835297819909 0.847001278626772 1.1129270611326845 1.0 16.24374542690034 -5.394941221557046 5.9936317750654 0.9154680281245849 1.2705456504516064 0.4664106397739235 0.1466441372089933 0.18535073164366447 8.173413856872136 0.0392413833021793 0.0829589613690858 4.027715426904913e-06 5.394941221557046 0.35507762232702145 KVSYS(ph)HIQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KVSYSHIQSK 10 1 E7EVA0;P27816-4;H0Y2V1;F8W9U4;P27816;P27816-6;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 KVS(0.383)YS(0.616)HIQS(0.001)K 58.21 0.035711 7656400.0 88054.0 68040.0 70726.0 68427.0 98652.0 78950.0 70584.0 84510.0 60371.0 52571.0 True False 102959.8030542253 74794.56153930505 72412.37606984859 64593.25703332725 79321.84877930766 74809.72301646815 63897.772536093304 82291.70204574648 61253.811664288936 62101.706148192985 1.65792229296459 1.2043881912168914 1.1660287705631034 1.0401204900745995 1.277289364482553 1.2046323306794517 1.0289213694647033 1.3251117746970464 0.9863466797211542 1.0 15.922345284351477 -4.745291253555321 3.369511581368123 1.14289749649457 1.7505754126523974 0.6659759784267348 0.11144032236541407 0.21222638518372672 3.5749249697901684 0.026380384415733725 0.35269169409781276 1.7976649317964592e-05 4.745291253555321 0.6076779161578274 KVT(ph)S(ph)VS(ph)T(ph)LKSEDIK ddPTM_PC-9_AZD4547_30min_R2 1 KVTSVSTLKSEDIK 14 2 E9PMQ6;Q00613-2;Q00613;A0A087X1F9;E9PI02 E9PMQ6 HSF1 Heat shock factor protein 1 4 KVT(1)S(1)VS(1)T(1)LKS(0.001)EDIK 70.089 0.032866 0.0 27416.0 31651.0 20590.0 13992.0 19717.0 20749.0 31616.0 22304.0 20414.0 23447.0 True False 36133.717711774516 41881.566780960544 20316.963146732985 10766.360574245064 16979.634890193807 19451.56174993631 34429.76275169241 18857.429294931982 21493.042363993012 22626.127666711356 1.5969907994878052 1.85102671556913 0.8979425664880463 0.475837524336303 0.7504436967875444 0.8596946873306288 1.5216816266067097 0.8334359980950667 0.9499213776476036 1.0 14.465702076215146 -5.266649586131364 24.796035160835885 0.9038559002216702 1.7240087859177302 0.6231879056049097 0.2527885875555046 233.8000332055696 1112689.6741484688 0.07131653978481041 0.15599158181095277 5.411908108301936e-06 5.266649586131364 0.82015288569606 KVTAEADSS(ph)SPTGILATSESK ddPTM_PC-9_AZD4547_30min_R2 1 KVTAEADSSSPTGILATSESK 21 1 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 KVTAEADS(0.029)S(0.476)S(0.242)PT(0.253)GILATSESK 76.152 0.00062486 27525000.0 76269.0 60232.0 79885.0 106040.0 102330.0 86773.0 74919.0 84908.0 69098.0 92757.0 True False 100520.95550624907 79700.81609904316 78825.67270406835 81594.11630166853 88123.2458443745 81347.07059266577 81586.64586266577 71787.41959173638 72750.37921363715 89509.60566303333 1.123018638744415 0.8904163470352422 0.8806392578782485 0.9115682690954606 0.9845116084649294 0.9088082780623999 0.9114848094606267 0.8020079974655049 0.8127661682201155 1.0 16.449754892080676 -7.366247969092767 2.4411790626126555 0.8572159087005838 0.9455792437626673 0.13949052116383387 0.08288172771720563 0.532743765313276 6.192717102622956 0.040980295453376794 0.02502648687109282 4.302808629041625e-08 7.366247969092767 0.08836333506208349 KVTAEADSSS(ph)PTGILATSESK ddPTM_PC-9_AZD4547_30min_R2 2 KVTAEADSSSPTGILATSESK 21 1 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 KVTAEADS(0.016)S(0.451)S(0.513)PT(0.02)GILATSESK;KVTAEADS(0.002)S(0.036)S(0.947)PT(0.016)GILATSESK 106.67 3.3018e-05 33957200.0 184461.0 177405.0 233406.0 287130.0 264660.0 243889.0 210172.0 266020.0 204718.0 237255.0 True False 243115.76097284982 234747.69690614237 230310.88393522904 220936.6146142783 227916.5273641377 228638.58227530125 228876.9008428869 224912.72153146515 215538.97553991948 228948.77466480198 1.0618784107003383 1.0253284703088297 1.0059494062478442 0.9650045733494138 0.9954913613223064 0.9986451450113464 0.9996860702922726 0.9823713704550465 0.941428823349173 1.0 17.80466531815653 -4.9926913783344204 1.4695797655454925 0.9843232546304266 1.0748114994666853 0.6576848721932532 0.01797197621017387 0.4975700402995282 1.331630564148468 0.005417026508490877 0.05903298690144902 1.016971123946954e-05 4.9926913783344204 0.09048824483625872 KVTAEADSSS(ph)PTGILATSESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KVTAEADSSSPTGILATSESK 21 1 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 KVTAEADS(0.009)S(0.223)S(0.638)PT(0.13)GILATSESK;KVTAEADSS(0.273)S(0.675)PT(0.052)GILATSESK 110.55 1.5762e-05 38874000.0 316510.0 278710.0 281280.0 368200.0 394830.0 339620.0 374950.0 329380.0 326250.0 285840.0 True False 370088.8916425471 306378.4868697789 287986.7819603403 347570.9477205065 317465.89581087005 321809.7293331596 339432.02159707807 320734.1240069576 331020.789045639 337660.5292918043 1.0960383566855052 0.9073565320541459 0.8528884988848185 1.0293502425334935 0.9401924959269309 0.953056994870293 1.005246370693635 0.9498715312673723 0.9803360485749067 1.0 18.365214020311427 -7.197249502794391 24.989150562023994 0.9796864831456383 0.9575653107136417 0.018926150219751525 0.06331149923780835 1019.9800311265973 397079.19266629464 0.02424479653236184 0.01877992742081029 6.349660381583931e-08 7.197249502794391 -0.022121172431996627 KVTAEADSSS(ph)PTGILATSESK ddPTM_PC-9_Lapatinib_30min_R1 2 KVTAEADSSSPTGILATSESK 21 1 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 KVTAEADSS(0.03)S(0.968)PT(0.001)GILATSESK;KVTAEADS(0.003)S(0.105)S(0.772)PT(0.12)GILATSESK 142.45 8.086399999999999e-05 64930000.0 323029.0 269731.0 296901.0 247875.0 286417.0 277549.0 239690.0 255674.0 287889.0 236780.0 True False 318422.54722373723 269106.45444172266 272490.9458510031 266104.5543867598 269570.515177488 265678.87626831984 252099.9753878226 267553.5474238259 255463.90921443317 277707.10751048167 1.1466128831856377 0.9690297697244411 0.9812170393972302 0.9582201794266864 0.9707008135083954 0.9566873482281766 0.9077908651592845 0.9634378818112441 0.9199041087012547 1.0 18.083204575752397 KVTAEADSSSPT(ph)GILATSESK ddPTM_PC-9_AZD4547_30min_R2 1 KVTAEADSSSPTGILATSESK 21 1 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 KVTAEADS(0.004)S(0.112)S(0.075)PT(0.809)GILATSESK 99.059 0.00060847 0.0 27372.0 23345.0 32185.0 44611.0 38587.0 35482.0 21735.0 40588.0 28509.0 34217.0 True False 36075.72662703139 30890.81471364331 31758.20587069459 34326.62318307937 33229.8611101034 33263.30493089978 23669.372893725784 34316.05721945387 30015.92753772297 33019.07324484423 1.092572355363258 0.9355445709993319 0.9618139684054725 1.0395998376011146 1.0063838213657945 1.0073966850687939 0.7168394072786899 1.0392798418354203 0.9090481527191202 1.0 15.011012007861478 KVTGTEGSSSTLVDYTSTS(ph)STGGSPVR ddPTM_PC-9_Lapatinib_30min_R1 1 KVTGTEGSSSTLVDYTSTSSTGGSPVR 27 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 KVTGTEGSSSTLVDY(0.001)TS(0.001)T(0.011)S(0.539)S(0.072)T(0.048)GGS(0.328)PVR 148.95 2.6095e-10 15918000.0 170630.0 155830.0 174810.0 156470.0 166100.0 173930.0 156600.0 169850.0 178480.0 139150.0 True False 168196.78491029018 155469.18520916643 160437.79658611375 167977.32576861864 156330.3245651644 166491.41935063293 164707.9817503153 177741.8510679099 158377.7029222792 163201.8920942796 1.0306056060497453 0.9526187669402381 0.9830633366274388 1.0292608965071333 0.9578952949568403 1.020156183326925 1.0092283835481861 1.0890918529622853 0.9704403600344685 1.0 17.316298257844323 -6.9601755196688915 24.958412442049664 1.0231970332234703 0.9901662755165284 0.11146900704423734 0.03677503437164932 277.5900380473247 173967.55571492386 0.012405944229758362 0.010941004464595203 1.096035145141503e-07 6.9601755196688915 -0.03303075770694197 KVTGTEGSSSTLVDYTSTS(ph)STGGSPVRK ddPTM_PC-9_AZD4547_30min_R2 1 KVTGTEGSSSTLVDYTSTSSTGGSPVRK 28 2 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 KVTGTEGSSSTLVDY(0.005)T(0.026)S(0.04)T(0.063)S(0.268)S(0.268)T(0.063)GGS(0.268)PVRK 92.39 2.5501e-08 6974500.0 25986.0 25321.0 31337.0 44328.0 42426.0 42248.0 25782.0 35986.0 32128.0 26425.0 True False 34249.00745762228 33505.518070857215 30921.450904767924 34108.86446077296 36535.88222606697 39606.225881310354 28076.548053647937 30425.190576014265 33826.22048938804 25499.868793144014 1.3431052424407217 1.3139486458795282 1.212612157168494 1.3376094103646363 1.4327870673550342 1.55319332042834 1.1010467654326401 1.1931508676701306 1.326525276023486 1.0 14.638202203419173 -10.617541003779817 4.641490814251064 0.9999807035591385 1.311361308608591 0.3806723490173912 0.11963173808020144 66525838.36692251 0.42353112000578275 13899.917621161614 0.03202410944084215 2.4124537507605937e-11 10.617541003779817 0.3113806050494524 KVTGTEGSSSTLVDYTSTSSTGGS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 2 KVTGTEGSSSTLVDYTSTSSTGGSPVR 27 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 KVTGTEGSSSTLVDYTSTS(0.002)S(0.003)T(0.003)GGS(0.992)PVR;KVTGTEGSSSTLVDYTSTS(0.024)S(0.024)T(0.024)GGS(0.927)PVR 187.7 2.8328e-24 27880000.0 97459.0 101402.0 135159.0 164502.0 150928.0 160087.0 115254.0 160367.0 131319.0 129497.0 True False 128448.93472686895 134178.21347581325 133366.7033486781 126578.60543056478 129974.25240691665 150076.73458297004 125511.38272341745 135585.96501705362 138260.25424694814 124963.34944581911 1.027892860558776 1.0737405332912389 1.0672465482089408 1.0129258377909116 1.0400989808877534 1.2009660052209103 1.004385552084101 1.0850058486615726 1.1064064372481808 1.0 16.93114550271654 KVTGTEGSSSTLVDYTSTSSTGGS(ph)PVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KVTGTEGSSSTLVDYTSTSSTGGSPVR 27 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 KVTGTEGSSSTLVDYTST(0.002)S(0.019)S(0.019)T(0.019)GGS(0.941)PVR;KVTGTEGSSSTLVDY(0.001)T(0.05)S(0.036)T(0.143)S(0.075)S(0.075)T(0.075)GGS(0.546)PVR;KVTGTEGSSSTLVDYTST(0.005)S(0.008)S(0.005)T(0.005)GGS(0.977)PVR 135.06 8.310200000000001e-11 24813000.0 113401.0 119908.0 139533.0 140367.0 143744.0 131912.0 141860.0 104516.0 119256.0 106313.0 True False 132597.549528156 131811.67379563508 142859.99590184895 132502.69206595427 115578.39507493765 124994.3025021958 128421.99382254061 101772.56574385596 120999.89338981357 125586.7053267553 1.0558247322689107 1.0495670975099114 1.137540757440459 1.0550694177477205 0.9203075657906805 0.9952829177020118 1.0225763426822 0.8103769063696751 0.9634769307387464 1.0 16.93832422231018 -6.165765490880159 4.9625534606087225 0.9484124970669808 1.0801496132175363 0.5055157639802413 0.05953831289371968 0.19000962928370244 7.565904269914501 0.018270875783915674 0.023816993320653315 6.827072409760731e-07 6.165765490880159 0.1317371161505555 KVTGTEGSSSTLVDYTSTSSTGGS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 1 KVTGTEGSSSTLVDYTSTSSTGGSPVR 27 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 KVTGTEGSSSTLVDYTSTS(0.001)STGGS(0.998)PVR 207.55 1.9669e-38 20433000.0 81347.0 81760.0 87431.0 70485.0 87179.0 90109.0 78072.0 78430.0 81506.0 73246.0 True False 80186.97686278724 81570.6897433195 80242.76067342001 75668.702031067 82051.30262050853 86255.24812433853 82114.18615077024 82074.1441227916 72325.93598377003 85906.47350584007 0.9334218201534719 0.9495290216723211 0.9340711752993209 0.8808265424365594 0.9551236277313903 1.0040599340685863 0.9558556276342548 0.9553895157529898 0.841914852654884 1.0 16.390479229689454 KVTGTLDANR ddPTM_PC-9_Lapatinib_30min_R1 1 KVTGTLDANR 10 1 Q16658;C9JFC0;A0A0A0MSB2 Q16658 FSCN1 Fascin 0 61.958 0.038975 11402000.0 108180.0 78598.0 106210.0 83708.0 89766.0 91765.0 80029.0 79779.0 99377.0 60057.0 False True 106637.33336221793 78416.01116004687 97477.82378245603 89864.1655617023 84486.14036674632 87840.42486466297 84172.51003509558 83485.82358755825 88184.11577379725 70437.77242907768 1.513922568598955 1.113266482681608 1.383885668454442 1.2757951091111612 1.1994436713882972 1.2470642076750462 1.1949910840784626 1.1852422458648642 1.2519435628460283 1.0 16.104061664693322 -14.439845995848431 0.050473555602725435 3.3162790167044717e-12 1.7556554276896377 0.47875238890875593 0.09616700709556468 482.4765352062674 1.8181403439841388 65.46289094843081 14.652799107554122 3.6320682786144315e-15 14.439845995848431 1.7556554276863214 KVTS(ph)PLQSPTK ddPTM_PC-9_Lapatinib_30min_R1 1 KVTSPLQSPTK 11 1 H0YDE2;A0A1B0GTN9;E9PKC0;Q6IQ23-3;Q6IQ23;Q6IQ23-2;A0A1B0GUM1;A0A1B0GUN0 H0YDE2 PLEKHA7 Pleckstrin homology domain-containing family A member 7 1 KVT(0.12)S(0.878)PLQS(0.002)PTK 56.773999999999994 0.036286 14306000.0 110280.0 92752.0 98568.0 91532.0 89945.0 83732.0 73991.0 99999.0 107690.0 80866.0 True False 108707.38697712471 92537.23844266603 90464.11952348292 98263.56862180076 84654.61193867386 80150.97754882532 77821.89193925651 104645.31860429754 95560.81817402641 94843.5803528281 1.146175487816063 0.9756826777143773 0.9538243831258466 1.0360592488837932 0.8925708163246241 0.8450859536370859 0.8205288291495417 1.1033463542287834 1.0075623233383864 1.0 16.533262505251827 -2.5396112011054046 1.2759145651971806 0.9498270130532528 68.20779641558129 0.313145589952757 0.08249237244509125 654.297739741864 4.16111712478292 0.026029484904083352 127693.94345597184 0.002886614566873395 2.5396112011054046 67.25796940252803 KVVDYSQFQES(ph)DDADEDYGR ddPTM_PC-9_AZD4547_30min_R2 4 KVVDYSQFQESDDADEDYGR 20 1 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 KVVDYSQFQES(1)DDADEDYGR;KVVDYSQFQES(1)DDADEDYGR;KVVDYSQFQES(1)DDADEDYGR;KVVDYSQFQES(1)DDADEDYGR 128.51 3.869e-06 67476800.0 236432.0 234664.0 271095.0 316583.0 296995.0 285249.0 256228.0 339287.0 263381.0 260357.0 True False 311612.4579088957 310514.5488953694 267500.1031696736 243599.6805085924 255762.37075686455 267412.33493698906 279031.79562059266 286857.99018963386 277302.7819570318 251241.9806765032 1.240288175844804 1.2359182492482614 1.0647110106734279 0.9695819140283288 1.0179921765788884 1.0643616732241363 1.110609759042902 1.1417597863909117 1.1037278929673948 1.0 17.938718022478113 -5.261665480481755 7.198186467069217 1.0613512432287442 1.2388904314879539 0.6741902266548692 0.04976550408682908 0.07763721785209154 31.23949134169521 0.01471711137643881 0.03469403501805939 5.474374695353321e-06 5.261665480481755 0.17753918825920967 KVVDYSQFQES(ph)DDADEDYGR ddPTM_PC-9_Lapatinib_30min_R1 12 KVVDYSQFQESDDADEDYGR 20 1 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 KVVDYSQFQES(1)DDADEDYGR;KVVDYSQFQES(1)DDADEDYGR;KVVDYSQFQES(1)DDADEDYGR;KVVDYSQFQES(0.999)DDADEDY(0.001)GR;KVVDYSQFQES(1)DDADEDYGR;KVVDYS(0.001)QFQES(0.99)DDADEDY(0.009)GR;KVVDYSQFQES(1)DDADEDYGR;KVVDYSQFQES(1)DDADEDYGR;KVVDYSQFQES(1)DDADEDYGR;KVVDYSQFQES(1)DDADEDYGR;KVVDYSQFQES(1)DDADEDYGR;KVVDYSQFQES(1)DDADEDYGR 131.94 5.8487000000000004e-06 620189600.0 1300613.3 1725066.0 1837617.0 1569982.0 1882486.6 1853150.9 1620271.9 1743568.7 1815810.0 1575626.5999999999 True False 1282066.3158387295 1721071.7156647386 1686535.2236667518 1685443.713586422 1771762.4392990565 1773895.9559127418 1704161.6509307036 1824581.2670124788 1611294.356473013 1847971.558419528 0.6937695063527995 0.931330197060327 0.9126413315089956 0.9120506784357074 0.9587606644846585 0.9599151825853104 0.9221795882985249 0.9873427211038607 0.8719259499053479 1.0 20.817511122158848 -4.760694048638291 6.128730302285585 0.9387001708892158 0.6852095338144615 0.8060181417996967 0.03619111844001757 0.05180141242239473 7.873042915776382 0.00844003242384766 0.055046646916849726 1.735025856674561e-05 4.760694048638291 -0.2534906370747543 KVVDYSQFQES(ph)DDADEDYGRDSGPPTK ddPTM_PC-9_AZD4547_30min_R2 1 KVVDYSQFQESDDADEDYGRDSGPPTK 27 2 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 KVVDYS(0.001)QFQES(0.995)DDADEDY(0.003)GRDS(0.002)GPPTK 51.628 0.004407899999999999 9419700.0 42869.0 31404.0 51648.0 67889.0 61147.0 52126.0 39173.0 55215.0 46058.0 52398.0 True False 56500.45026940696 41554.72886130882 50963.11377379632 52238.23992459421 52657.794524049365 48866.55297976673 42659.3211118436 46682.79046447584 48492.53185072941 50563.56196870991 1.1174143606490965 0.8218315174675391 1.0079019710939998 1.0331202528200176 1.041417820932699 0.9664381043805156 0.8436771352904753 0.9232496415771579 0.9590410557060416 1.0 15.625810477826843 -7.006684846847306 24.426407975164746 0.9222334531538477 0.9967883781512805 0.15255442936722563 0.07884820740617823 422.4296724616923 1543561.5782267211 0.02811796141886549 0.02389726043499152 9.847254292495261e-08 7.006684846847306 0.07455492499743277 KVVDYSQFQES(ph)DDADEDYGRDSGPPTK ddPTM_PC-9_Lapatinib_30min_R1 2 KVVDYSQFQESDDADEDYGRDSGPPTK 27 2 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 KVVDYSQFQES(0.992)DDADEDY(0.006)GRDSGPPTK;KVVDYS(0.001)QFQES(0.964)DDADEDY(0.034)GRDSGPPTK 85.571 2.3799000000000003e-06 21925500.0 56686.0 38740.0 42721.0 39034.0 38427.0 37351.0 35998.0 34473.0 46412.0 35816.0 True False 55877.647245060776 38650.29991017852 39208.64428782891 41904.69057360682 36166.79941038876 35753.584799433644 37861.80030043324 36074.74142987377 41184.59181997319 42006.747878179835 1.3302064565223366 0.9200974096415399 0.9333891878879682 0.9975704545167605 0.8609759440381577 0.8511390813475861 0.9013266251944331 0.8587844394546094 0.9804280002681733 1.0 15.358333477641537 -4.761393082782565 8.242598460210546 0.9157910290052597 1.3346892700727369 0.8375927149729815 0.0537682219453064 0.033626642308902 22.398714160564502 0.013483853392324312 0.07844964599814484 1.7322354303573118e-05 4.761393082782565 0.4188982410674772 KVVDYSQFQES(ph)DDADEDYGRDSGPPTKK ddPTM_PC-9_Lapatinib_30min_R1 2 KVVDYSQFQESDDADEDYGRDSGPPTKK 28 3 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 KVVDY(0.001)S(0.004)QFQES(0.978)DDADEDY(0.008)GRDS(0.005)GPPT(0.004)KK;KVVDY(0.002)S(0.002)QFQES(0.993)DDADEDY(0.001)GRDSGPPT(0.001)KK 46.398999999999994 0.023469 43136000.0 132584.0 40615.0 52813.0 43926.0 30929.0 33804.0 22423.1 26071.3 55738.0 28363.0 True False 130693.32784707204 40520.95846287815 48470.91900407552 47156.4645728404 29109.817028753598 32358.28172097277 23584.058400929058 27282.667775959973 49460.19949283947 33265.50675867811 3.9287941348729802 1.2181073553706583 1.4570924578333897 1.4175784218449792 0.87507511128354 0.9727277553807694 0.7089643507317558 0.8201488699354514 1.4868313851835908 1.0 15.021739391103953 -3.2188673190483095 1.4031526266376135 1.0386053359613552 199.99968620358155 0.8970830933301872 0.2845890077689682 29.453467919205647 1.089958644125328 0.08408437459443145 18044.492534152123 0.0006041331694157035 3.2188673190483095 198.96108086762018 up KVVGCSCVVVK ddPTM_PC-9_Lapatinib_30min_R1 2 KVVGCSCVVVK 11 1 P25398 P25398 RPS12 40S ribosomal protein S12 0 ; 108.72 0.0013608 13365800.0 109342.0 94392.0 127111.0 106304.0 104727.0 90074.0 93457.0 73927.0 117131.0 91043.0 False True 107782.76302913282 94173.44112342734 116660.42424264943 114121.95077974831 98567.163761204 86221.7449927495 98295.746171387 77361.91830378197 103938.47333588898 106779.66124282824 1.0093941278201233 0.8819417483378879 1.0925341294851207 1.0687611240891928 0.9230893094617697 0.8074734831446237 0.9205474621974318 0.7245005032171136 0.9733920498166959 1.0 16.70427735162673 -6.4882986955592274 6.4145051430195315 0.869450929659924 1.0084452881567103 0.3012284874518889 0.09057932681235467 0.2264028618872502 28.96913432516496 0.027970045295849778 0.030912649321646935 3.248637883340231e-07 6.4882986955592274 0.13899435849678632 KVVNPLFEK ddPTM_PC-9_Lapatinib_30min_R1 1 KVVNPLFEK 9 1 P62424;Q5T8U3 P62424 RPL7A 60S ribosomal protein L7a 0 117.02 0.00052915 0.0 74060.0 68749.0 61237.0 60811.0 67012.0 65600.0 71358.0 56066.0 61362.0 68322.0 False True 73003.89081905923 68589.81591442584 56202.33024165584 65283.24379954922 63070.485910661024 62794.44092106897 75052.5680826244 58671.031038995825 54450.76538949401 80131.36666665728 0.9110526109301491 0.8559671295730703 0.7013774078689422 0.8147027377072508 0.787088608796993 0.7836437032490772 0.9366190944282725 0.7321855782525781 0.6795187409695211 1.0 16.290079462089068 -11.785982573059602 2.4249385968940884 1.866865422220801 0.8005309159153388 0.3608103863883264 0.079763010818216 11279577.052116675 1877100.5211548314 53723786.76875362 0.02013333122373102 1.6368822033037313e-12 11.785982573059602 -1.0663345063054623 KVVVS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KVVVSPTK 8 1 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 1 KVVVS(0.985)PT(0.015)K;KVVVS(0.99)PT(0.01)K 64.12100000000001 0.025384999999999998 1374100000.0 283543.0 327400.0 310221.0 344270.0 355530.0 300484.0 335754.0 356220.0 276817.0 220622.0 True False 331541.2296704772 359902.1082887791 317617.8451596942 324981.6680384 285866.44869345956 284726.0900681499 303948.95047154464 346869.60244628764 280864.92493868736 260619.02215720838 1.272129819712422 1.3809510346166598 1.218705536267815 1.2469606606165813 1.0968748417796674 1.0924992646791525 1.1662577349714678 1.3309450690711744 1.0776839027861382 1.0 17.991582862143055 -1.5228787452803376 0.1019535038275291 0.947815455782582 2.032728352117331 0.46560910797433075 0.08480154088066665 128.92035637336144 0.9323977587626388 1.1012127750309741 19.576555368749432 0.029999999999999995 1.5228787452803376 1.084912896334749 KVVVS(ph)PTKK ddPTM_PC-9_AZD4547_30min_R2 1 KVVVSPTKK 9 2 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 1 KVVVS(0.796)PT(0.204)KK 107.85 0.0053097000000000005 0.0 112780.0 97410.0 105300.0 134760.0 145260.0 117490.0 127080.0 121050.0 130730.0 131380.0 True False 148641.69403027152 128895.87754362806 103903.65319820229 103693.16402124528 125093.1563701149 110143.33172683096 138389.87381341963 102344.5039522741 137640.1209094155 126780.42618895952 1.1724340933254864 1.016685946074322 0.8195559545078306 0.8178956889346317 0.9866914012709672 0.8687723731317021 1.091571293561964 0.8072579263910584 1.0856575028724875 1.0 16.9519724973594 -10.16272271264909 15.26247569413526 1.0000101359954203 0.9531763860024659 0.002430674246232445 0.124300675989236 0.0 0.0 0.11887156391254518 0.028830589052575555 6.875072579786034e-11 10.16272271264909 -0.04683374999295442 KVVVS(ph)PTKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KVVVSPTKK 9 2 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 1 KVVVS(0.824)PT(0.176)KK 100.04 0.012452 0.0 35548.0 31219.0 31942.0 40025.0 42595.0 41606.0 41587.0 46103.0 41068.0 30911.0 True False 41565.574294996324 34318.21600081674 32703.618420709594 37782.52901280082 34248.815520765944 39424.108116822994 37647.57829619341 44892.84510016631 41668.54180697719 36514.919608658616 1.138317562806302 0.939840929916193 0.895623453952634 1.0347148348600395 0.9379403237860252 1.0796712286195076 1.031019065622322 1.2294384208235003 1.1411374378898131 1.0 15.156198433884427 -7.219911416352232 1.801545085202823 1.131323987608944 0.985884774797371 0.258517929826781 0.08622994800562665 0.4098088583108257 2.601702784046563 0.04389608335829512 0.028223486401161242 6.026825035241738e-08 7.219911416352232 -0.14543921281157302 KVVVSPT(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 KVVVSPTK 8 1 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 1 KVVVS(0.087)PT(0.913)K 72.531 0.027527999999999997 1362200000.0 204550.0 194850.0 204090.0 248180.0 215690.0 199400.0 245260.0 238060.0 206740.0 238140.0 True False 269592.6450956911 257831.45200057383 201383.63324996276 190965.9353427772 185745.16658040797 186931.48647825458 267087.6648684242 201273.29707458318 217667.85433192464 229802.7910841744 1.1731478274210434 1.1219683224218666 0.8763324078870653 0.8309991991038453 0.8082807249820192 0.8134430639259882 1.1622472625695512 0.8758522737039293 0.9471941280826095 1.0 17.810036794870115 -3.3359461478746284 8.663396184921643 0.9532643566764809 1.0489162885691672 0.0 0.13788939886987 0.0 0.0 0.033647927743724396 0.0 0.0004613747810716543 3.3359461478746284 0.09565193189268628 KVVVSPT(ph)KK ddPTM_PC-9_AZD4547_30min_R2 1 KVVVSPTKK 9 2 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 1 KVVVS(0.143)PT(0.857)KK 72.73100000000001 0.028589999999999997 0.0 8242400.0 6390700.0 8622900.0 8423600.0 7726800.0 8035000.0 7233000.0 8449000.0 7560700.0 8670200.0 True False 10863311.747429632 8456368.798050119 8508554.711897237 6481669.163322656 6654067.194276485 7532570.179803275 7876722.987822326 7143401.188705164 7960343.166525034 8366658.937003488 1.2984049940632956 1.0107223040549518 1.0169596700382015 0.7747022093438006 0.7953075707254339 0.9003080245674576 0.9414418643248016 0.853793759550998 0.9514363172279645 1.0 22.99622019481162 -4.553973430133705 1.2979983408099685 0.8864555795053842 1.6639921179044455 0.7253184268535365 0.0738090472563256 1.1647956557811727 1.1845382190850222 0.022152644003296286 1.3848726602817667 2.79271469255897e-05 4.553973430133705 0.7775365383990612 KVYEDSGIPLPAES(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 KVYEDSGIPLPAESPK 16 1 Q8IXM2-2;F8W038;F8W1H0;H0YIS7;Q8IXM2;Q8IXM2-3 Q8IXM2-2 BAP18;C17orf49;RNASEK-C17orf49 Chromatin complexes subunit BAP18 1 KVYEDSGIPLPAES(1)PK;KVYEDSGIPLPAES(1)PK;KVYEDSGIPLPAES(1)PK;KVYEDSGIPLPAES(1)PK 128.4 9.6753e-06 54227000.0 468776.0 493071.0 321503.0 279770.0 324302.0 390411.0 464078.0 354993.0 401715.0 354538.0 True False 617837.0168534716 652446.5582210675 317239.6601536716 215273.3489034121 279278.26515999506 365998.53845266724 505380.04296178743 300136.98877760937 422948.83478257345 342125.7325329686 1.8058770741365804 1.9070373730458732 0.9272604483882284 0.6292229096876467 0.8163030096927383 1.0697778730145595 1.4771763562481726 0.8772710154115255 1.2362380100766504 1.0 18.384167093016593 -5.260585528494111 24.999677525834535 0.9989107015703247 1.8564573019830748 0.7054706489305205 0.22026052724539696 41.12901754109921 1204157.846686048 0.062002116935664923 0.14576582631548266 5.48800466046616e-06 5.260585528494111 0.8575466004127501 KVYEDSGIPLPAES(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 KVYEDSGIPLPAESPK 16 1 Q8IXM2-2;F8W038;F8W1H0;H0YIS7;Q8IXM2;Q8IXM2-3 Q8IXM2-2 BAP18;C17orf49;RNASEK-C17orf49 Chromatin complexes subunit BAP18 1 KVYEDSGIPLPAES(1)PK;KVYEDSGIPLPAES(1)PK;KVYEDSGIPLPAES(1)PK;KVYEDSGIPLPAES(1)PK;KVYEDSGIPLPAES(1)PK 123.61 1.762e-05 58323800.0 414382.0 491366.0 330021.0 402747.0 399019.0 278624.0 427121.0 329209.0 280973.0 310177.0 True False 484528.68818243383 540145.5691552364 337889.95225161145 380182.39131339075 320834.0913318576 264012.46695048024 386661.00679174846 320567.61257576756 285081.69857630745 366409.63474021887 1.3223688523528054 1.4741576583765181 0.9221644853612334 1.0375884127144654 0.8756158706343137 0.7205390959155937 1.0552697585746829 0.874888600576912 0.7780409452890829 1.0 18.4830979140321 -5.268293195625115 24.073288104276223 0.9055793716740751 1.3982632740176701 0.7730379931497798 0.10624949094158796 125.71659796047426 441568.4955660063 0.027863326329120714 0.06023008738096805 5.3914651756372165e-06 5.268293195625115 0.49268390234359505 KVYEDSGIPLPAES(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 KVYEDSGIPLPAESPK 16 1 Q8IXM2-2;F8W038;F8W1H0;H0YIS7;Q8IXM2;Q8IXM2-3 Q8IXM2-2 BAP18;C17orf49;RNASEK-C17orf49 Chromatin complexes subunit BAP18 1 KVYEDSGIPLPAES(1)PK;KVYEDSGIPLPAES(1)PK;KVYEDSGIPLPAES(1)PK;KVYEDSGIPLPAES(1)PK 121.0 3.7792e-05 77487000.0 496550.0 611280.0 396215.0 496262.0 521160.0 423905.0 552982.0 467841.0 376169.0 452736.0 True False 489469.10594388115 609864.6187169302 363639.73213412886 532758.7629615023 490506.39343998267 405775.5713208189 581612.7021982941 489578.6007975384 333800.88598482043 530990.8143671997 0.9218033395308328 1.1485408075160908 0.6848324345638466 1.0033295276424123 0.9237568337684642 0.7641856701502376 1.0953347712642116 0.9220095480954531 0.6286377785699035 1.0 19.01832737843891 -5.238614326994812 24.98466487224427 0.884816973999184 1.0351720354416147 0.1511502197308804 0.14846150591809013 1537.338153712201 1682788.8725198347 0.03638138109918753 0.09611355228807258 5.7727888540898325e-06 5.238614326994812 0.15035506144243072 KVYEDSGIPLPAES(ph)PKKGPK ddPTM_PC-9_AZD4547_30min_R2 1 KVYEDSGIPLPAESPKKGPK 20 3 Q8IXM2-2;F8W038;F8W1H0;H0YIS7;Q8IXM2;Q8IXM2-3 Q8IXM2-2 BAP18;C17orf49;RNASEK-C17orf49 Chromatin complexes subunit BAP18 1 KVYEDSGIPLPAES(1)PKKGPK 63.691 0.010634999999999999 4952800.0 34768.0 20508.0 25698.0 42722.0 42166.0 30633.0 25108.0 30689.0 25897.0 35312.0 True False 45823.50078067465 27136.809944202058 25357.22772922508 32873.10294832027 36311.9787381403 28717.51366744414 27342.563359358963 25946.72021306346 27265.86255022667 34075.73762813629 1.344754478413352 0.7963674987858584 0.7441431791130958 0.9647070096342389 1.0656256112313047 0.8427554520120535 0.8024056194393939 0.7614426574184939 0.8001547273246196 1.0 15.05645726654138 -6.925692802642318 9.87451774599845 0.8213274711443889 0.9583429601444411 0.14488106167110626 0.16410393621360467 0.7682828519347435 96.03462721440086 0.05847943562066172 0.05157474904884489 1.186607796101002e-07 6.925692802642318 0.13701548900005223 KWDGS(ph)EEDEDNSK ddPTM_PC-9_AZD4547_30min_R2 5 KWDGSEEDEDNSK 13 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 KWDGS(0.999)EEDEDNS(0.001)K;KWDGS(0.587)EEDEDNS(0.413)K;KWDGS(0.991)EEDEDNS(0.009)K;KWDGS(1)EEDEDNSK;KWDGS(1)EEDEDNSK 197.88 1.1324e-06 55742400.0 183099.0 181564.0 187932.0 215616.0 209979.0 207624.0 198789.0 209166.0 184449.0 199781.0 True False 241320.6733042095 240251.0123224642 185439.8988874124 165909.0624339925 180827.04035137186 194641.2384581802 216480.8358946797 176844.20085651605 194198.59757990358 192786.7279986038 1.251749411432291 1.2462009953517348 0.961891416554128 0.8605834237468569 0.9379641546314404 1.009619492372887 1.122903210931862 0.9173048512851818 1.007323479141728 1.0 17.556646210083187 -5.25937000972925 24.425554896283966 0.9750408948830721 1.2489752483309124 0.7344271806553643 0.06536131681622706 66.8017780357 788466.1007683281 0.018253137511578643 0.04362068400225985 5.503386197274475e-06 5.25937000972925 0.27393435344784034 KWDGS(ph)EEDEDNSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 KWDGSEEDEDNSK 13 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 KWDGS(1)EEDEDNSK;KWDGS(0.998)EEDEDNS(0.002)K;KWDGS(0.97)EEDEDNS(0.03)K;KWDGS(1)EEDEDNSK;KWDGS(1)EEDEDNSK 181.51 7.853699999999999e-27 30426100.0 76398.0 72815.0 74974.0 92037.0 99582.0 85707.0 93938.0 96539.0 82090.0 73100.4 True False 89330.67247071932 80043.59198242973 76761.66450047845 86880.46527797989 80069.62195536846 81212.37404144942 85039.51258777537 94004.9535415257 83290.41095097778 86352.92385755187 1.0344834717823748 0.9269355154026975 0.8889295355777971 1.006109132115761 0.927236952479474 0.940470460217626 0.9847901934166919 1.0886134405430978 0.9645349251679535 1.0 16.397957406908468 -7.525642792437183 24.993996316049405 1.0232848807177968 0.9519569540555939 0.25700430945260677 0.04831789946142069 105.58273582645572 954701.0671534708 0.02183584003230082 0.01270229497263892 2.980967269373503e-08 7.525642792437183 -0.07132792666220289 KWDGS(ph)EEDEDNSK ddPTM_PC-9_Lapatinib_30min_R1 4 KWDGSEEDEDNSK 13 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 KWDGS(0.79)EEDEDNS(0.21)K;KWDGS(1)EEDEDNSK;KWDGS(1)EEDEDNSK;KWDGS(1)EEDEDNSK 217.79 2.0866999999999998e-14 78936500.0 163432.0 131906.0 127132.0 149200.0 141142.0 131828.0 123739.0 134503.0 152475.0 116601.0 True False 161101.42971024173 131600.5797612803 116679.69770371146 160172.66571660954 132840.3050558484 126190.02374607744 130145.59996042313 140752.50040734265 135301.6598670691 136755.32748893372 1.1780267187271232 0.9623067867094937 0.8532003823628239 1.1712352904830765 0.9713720664125344 0.9227430189605503 0.9516674951544726 1.0292286449954382 0.9893703035299868 1.0 17.061237510687953 KWDGS(ph)EEDEDNSKK ddPTM_PC-9_AZD4547_30min_R2 1 KWDGSEEDEDNSKK 14 2 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 KWDGS(0.998)EEDEDNS(0.002)KK 79.565 0.035493000000000004 7345100.0 12177.0 13600.0 11828.0 14912.0 11778.0 16261.0 15262.0 14130.0 14153.0 15007.0 True False 16049.032702665545 17995.934037504772 11671.152991722096 11474.268788103365 10142.828003078697 15244.1970994127 16620.288433588365 11946.533175098142 14901.09868607785 14481.609497775305 1.1082354281912539 1.2426749968827253 0.8059292714331955 0.7923338072239875 0.7003936962004713 1.0526590363974768 1.1476824061677404 0.8249451262260175 1.0289670280342105 1.0 13.821934333173516 -5.2560513776538675 24.998758815744274 0.913455184220861 1.1754552284779736 0.36359942473897766 0.13548858178236875 490.8744643890465 2277496.6780244587 0.03726128194988202 0.09276176237648476 5.545601038294532e-06 5.2560513776538675 0.26200004425711254 KWDGSEEDEDNS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 KWDGSEEDEDNSK 13 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 KWDGS(0.181)EEDEDNS(0.819)K 180.95 0.00013166 8879800.0 17640.0 18591.0 21133.0 22493.0 23596.0 22532.0 19481.0 21262.0 21851.0 20908.0 True False 23249.153065206545 24600.177183180247 20852.762611943093 17307.586363385803 20320.102696607642 21123.070478074347 21214.771260302387 17976.446452154054 23005.99925029936 20176.01728389992 1.1523162742212225 1.2192781576773688 1.0335420672237035 0.8578296756910954 1.0071414199680875 1.0469395510941675 1.051484589935962 0.8909809205258223 1.1402646481998064 1.0 14.300353796221659 -5.349856944890613 5.071503986582644 0.9959037839159985 1.184956135322719 0.4740713759739572 0.07712585591211472 0.16685645435461433 7.057326260518544 0.01997628798028194 0.04336417486701725 4.468307524263903e-06 5.349856944890613 0.1890523514067204 KWDGSEEDEDNS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KWDGSEEDEDNSK 13 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 KWDGS(0.029)EEDEDNS(0.971)K 135.04 7.2301e-05 5724600.0 15738.0 14321.0 12739.0 16828.0 16590.0 16712.0 15547.0 13681.0 16804.0 18320.0 True False 18402.132560331167 15742.694235808207 13042.746072926528 15885.18171711211 13339.30859231147 15835.593300205399 14074.275609467351 13321.888246217713 17049.72670995531 21641.27097895981 0.8503258694104513 0.727438524803541 0.6026793013038382 0.7340225873312194 0.6163828642633921 0.7317312054177023 0.6503442253068555 0.6155779047898615 0.7878338904647276 1.0 14.401497609823105 -8.585479051253815 5.245397707606416 0.9999707398232999 0.6886939563584344 0.6337148655475031 0.07142536405847016 0.25450794369321056 19.67480451111404 0.06844360399308114 0.017782001321532084 2.5972930221097064e-09 8.585479051253815 -0.3112767834648654 KWDGSEEDEDNS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 KWDGSEEDEDNSK 13 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 KWDGS(0.223)EEDEDNS(0.777)K 118.52 0.00035562 14700000.0 24104.0 19262.0 20515.0 17691.0 16128.0 14890.0 15433.0 19635.0 16928.0 17600.0 True False 23760.272539867754 19217.40002245375 18828.33589019008 18992.05515544597 15179.38274886798 14253.189410285311 16232.045225751055 20547.313781091612 15021.390380257397 20642.136549474122 1.1510568435064958 0.9309792121757536 0.912131156823965 0.9200624707586198 0.7353590900092505 0.6904900263654358 0.7863549001745452 0.9954063491366195 0.727705213278423 1.0 14.333304683150015 -3.8495853392112105 0.8454287323713766 0.8241626437620317 2.3335202414090643 0.4510683980116631 0.10345547220585138 8.858077443288362 1.5225023437299685 0.03677109727445907 18.068765929040534 0.00014138868678770686 3.8495853392112105 1.5093575976470326 KWPQGAVPQLPPS(ph)APATSEMTTTPERPR ddPTM_PC-9_AZD4547_30min_R2 1 KWPQGAVPQLPPSAPATSEMTTTPERPR 28 2 F8VPD4;P27708;H7BZB3 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 KWPQGAVPQLPPS(0.829)APAT(0.066)S(0.023)EMT(0.027)T(0.027)T(0.027)PERPR 56.946999999999996 0.0069946 18452000.0 37289.0 30525.0 52673.0 66959.0 48871.0 50959.0 43444.0 60469.0 51745.0 44690.0 True False 49146.12634061714 40391.60930109069 51974.52160407322 51522.63705623747 42086.10522486491 47772.52567424957 47310.43183782022 51124.90548938498 54480.13506048881 43125.416702577335 1.1396093092749173 0.9366079771393082 1.2051946526691075 1.1947162716495743 0.9759002565730498 1.1077580073885873 1.0970428915297363 1.1854935997947023 1.2632952728601199 1.0 15.396250776544138 -7.745386953973816 16.27763184374245 1.1682947919217979 1.0919469460819817 0.051169631409758054 0.10058593148522639 9.236414353335316 9367.99457340919 0.04720667424751242 0.026876802144661222 1.79726884494774e-08 7.745386953973816 -0.07634784583981613 KWPQGAVPQLPPS(ph)APATSEMTTTPERPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KWPQGAVPQLPPSAPATSEMTTTPERPR 28 2 F8VPD4;P27708;H7BZB3 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 KWPQGAVPQLPPS(0.187)APAT(0.163)S(0.163)EMT(0.163)T(0.163)T(0.163)PERPR 55.67 0.0080859 21034000.0 77279.0 77549.0 82276.0 99827.0 95838.0 88479.0 91714.0 77792.0 89183.0 70731.0 True False 90360.8083701762 85247.55221651336 84237.77187346751 94234.01683350075 77059.23187883962 83839.00548162234 83026.18596814119 75750.04242743713 90487.13265734029 83553.97039371205 1.081466361734695 1.0202693159262335 1.0081839495661709 1.1278221296901103 0.9222689420470532 1.003411388909075 0.9936833112408194 0.9066001540141986 1.0829782502370469 1.0 16.350420764762553 -6.26914371794429 24.997247328410825 0.9815260527927688 1.0529770389833157 0.305285237037073 0.054658529446400414 749.119155351649 2430565.9142822386 0.016168997894069462 0.01867664391447297 5.380916862444752e-07 6.26914371794429 0.0714509861905469 KWPQGAVPQLPPSAPAT(ph)SEMTTTPERPR ddPTM_PC-9_AZD4547_30min_R2 1 KWPQGAVPQLPPSAPATSEMTTTPERPR 28 2 F8VPD4;P27708;H7BZB3 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 KWPQGAVPQLPPS(0.041)APAT(0.192)S(0.192)EMT(0.192)T(0.192)T(0.192)PERPR 47.175 0.012251999999999999 9777200.0 20425.0 19063.0 27264.0 34597.0 30084.0 26732.0 21870.0 33511.0 23933.0 25973.0 True False 26919.72513360792 25224.741952717155 26902.461546018847 26621.196168321643 25907.35588763962 25060.44381412584 23816.387632196143 28332.64495617223 25198.04951981212 25063.693175565935 1.0740526124797678 1.006425580461072 1.073363823821682 1.0621417993687412 1.0336607500803654 0.9998703558403251 0.9502345670036464 1.1304257819351669 1.0053605964334564 1.0 14.613311393311411 -6.504873080545906 8.417659094520172 1.0206512153501581 1.0515182718039784 0.12116352064989266 0.046078733895838296 0.5826428081223717 231.9604929212975 0.014849778990669853 0.016127831978122526 3.126993074951456e-07 6.504873080545906 0.030867056453820263 KWPQGAVPQLPPSAPAT(ph)SEMTTTPERPR ddPTM_PC-9_Lapatinib_30min_R1 1 KWPQGAVPQLPPSAPATSEMTTTPERPR 28 2 F8VPD4;P27708;H7BZB3 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 KWPQGAVPQLPPS(0.001)APAT(0.235)S(0.235)EMT(0.176)T(0.176)T(0.176)PERPR 85.573 2.0914e-07 8697900.0 44681.0 44285.0 55705.0 46496.0 46815.0 43090.0 38085.0 40089.0 46640.0 32941.0 True False 44043.840746508096 44182.46080336229 51125.14992751834 49915.47094610911 44061.43374183128 41247.14114769605 40056.8549486638 41951.68129208972 41386.91205902675 38634.807958876525 1.1400041328894148 1.1435920905933006 1.323292456427808 1.2919818573768995 1.140459499338807 1.067616052125848 1.0368074041237871 1.0858519430650135 1.071233797850881 1.0 15.237613606350571 -6.5689232897988825 3.396349907066885 1.0569029231111093 1.225833895153873 0.6637636688531999 0.0576583257777592 0.16416653462652697 3.918725144450914 0.021631156539321163 0.02228912911715642 2.698215981009499e-07 6.5689232897988825 0.16893097204276364 KWPQGAVPQLPPSAPATS(ph)EMTTTPERPR ddPTM_PC-9_Lapatinib_30min_R1 1 KWPQGAVPQLPPSAPATSEMTTTPERPR 28 2 F8VPD4;P27708;H7BZB3 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 KWPQGAVPQLPPS(0.055)APAT(0.071)S(0.219)EMT(0.219)T(0.219)T(0.219)PERPR 66.378 8.672e-05 11427000.0 48485.0 55611.0 51706.0 43232.0 41073.0 47831.0 37095.0 38825.0 55218.0 32729.0 True False 47793.595008939956 55482.23614622968 47454.93227093193 46411.42549772431 38657.16689262493 45785.37962950681 39015.59759277103 40628.95123763089 48998.76736868225 38386.16404134877 1.2450734842235787 1.4453706832093298 1.2362509632328584 1.2090665128125566 1.0070599096847563 1.192757358619834 1.0163974069079746 1.0584269684740115 1.2764694934326288 1.0 15.228298777321488 -5.782041660131855 2.0891115356139536 1.0969699709355962 1.341862050715484 0.5065802275308071 0.09700484537958765 0.2411737183301789 2.149173714506658 0.028180973491322526 0.05361384603467784 1.6518033397441656e-06 5.782041660131855 0.2448920797798877 KWPQGAVPQLPPSAPATSEMTTT(ph)PERPR ddPTM_PC-9_AZD4547_30min_R2 1 KWPQGAVPQLPPSAPATSEMTTTPERPR 28 2 F8VPD4;P27708;H7BZB3 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 KWPQGAVPQLPPS(0.017)APAT(0.017)S(0.067)EMT(0.275)T(0.275)T(0.348)PERPR 63.115 0.00033196 12678000.0 27607.0 26995.0 32157.0 51726.0 46657.0 40553.0 36621.0 47303.0 31954.0 37003.0 True False 36385.45173872772 35720.60583400304 31730.577168989475 39801.36985873358 40179.48090844307 38017.21449926102 39880.19805572266 39993.408264803045 33643.02320461609 35707.53623283664 1.018985222096272 1.0003660180047478 0.8886240977838747 1.1146490085230876 1.125238119103105 1.0646832156484771 1.1168566152443988 1.1200271002742865 0.9421827085812203 1.0 15.123940973084403 -5.778193288061573 24.99344007742185 1.0782381452596246 0.9724291719738523 0.32802212765703287 0.06446683633085373 248.96628989529262 371406.4241981645 0.017958396658727154 0.026717630019236167 1.6665053489232888e-06 5.778193288061573 -0.10580897328577232 KWS(ph)LNTYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KWSLNTYK 8 1 P53367;P53367-2 P53367 ARFIP1 Arfaptin-1 1 KWS(0.642)LNT(0.338)Y(0.02)K;KWS(0.943)LNT(0.056)YK 92.943 0.011158 61530000.0 79932.0 79596.0 53995.0 72405.0 63705.0 58376.0 59868.0 65046.0 48533.0 42798.0 True False 93462.90887103746 87497.76484836184 55282.44557717784 68348.38259017715 51222.4625601689 55314.659794925254 54196.86963321485 63338.61142193385 49242.70330958468 50556.9386112184 1.8486663045356624 1.7306776725785846 1.0934690093143984 1.3519090448845115 1.0131638498538917 1.0941061961898764 1.0719966659767006 1.252817380993066 0.9740048480439024 1.0 15.625621485783372 -5.21710388004489 4.086954811086468 1.1169415304607386 1.8218144537807288 0.8565236139394303 0.11202123359860051 0.07149031357418621 2.599214690171338 0.0283707208803699 0.08029755580465527 6.065912200775896e-06 5.21710388004489 0.7048729233199902 KWS(ph)LNTYK ddPTM_PC-9_Lapatinib_30min_R1 2 KWSLNTYK 8 1 P53367;P53367-2 P53367 ARFIP1 Arfaptin-1 1 KWS(0.998)LNT(0.002)YK;KWS(0.957)LNT(0.042)Y(0.001)K 95.48299999999999 0.0094205 64884000.0 204520.0 212950.0 182120.0 169831.0 154591.0 177288.0 184050.0 223985.0 144857.0 161761.0 True False 201603.50729562543 212456.927358609 167146.79660353033 182320.938279608 145498.26131759994 169705.80551851323 193579.20843643352 234392.16079744417 128541.67924816544 189721.17331701636 1.0626305107166618 1.1198377263016508 0.8810128763236923 0.9609941531141447 0.766905763725582 0.8945011384414207 1.0203352902154497 1.2354559941803882 0.6775294343840975 1.0 17.533521170238693 -5.255594048531508 24.692633653626547 0.9352998673180583 1.0912341309083158 0.16973175460538936 0.1425556566354132 734.8048331108783 3104033.96260978 0.03662132485350715 0.09145875633003642 5.551443849499627e-06 5.255594048531508 0.15593426359025753 KWS(ph)NSQPADLAHMGR ddPTM_PC-9_AZD4547_30min_R2 1 KWSNSQPADLAHMGR 15 1 Q9BRG2;Q9BRG2-2;M0QZQ6 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 KWS(0.943)NS(0.057)QPADLAHMGR 62.556000000000004 0.019547 6964800.0 20526.0 13871.0 28317.0 51658.0 33618.0 18056.0 22008.0 22044.0 20242.0 29302.0 True False 27052.841032677403 18354.529487810938 27941.498078000892 39749.04620814402 28950.720988919977 16926.95546565376 23966.6693648547 18637.60632072636 21311.950795137964 28276.14589883468 0.9567372133906096 0.6491170880741342 0.9881650129394906 1.4057448405577142 1.0238566844469812 0.5986302209011928 0.8475932133962578 0.6591282414303308 0.7537077673664244 1.0 14.78729787057508 -6.739729692821098 24.967400653857524 0.7552437312673295 1.0063272840107584 0.254876135896159 0.1980990375176181 343.6882498718201 395260.55303669564 0.07025298902554188 0.07019379215904692 1.820833802572199e-07 6.739729692821098 0.251083552743429 KWS(ph)NSQPADLAHMGR ddPTM_PC-9_Lapatinib_30min_R1 1 KWSNSQPADLAHMGR 15 1 Q9BRG2;Q9BRG2-2;M0QZQ6 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 KWS(0.86)NS(0.14)QPADLAHMGR 65.28699999999999 0.015685 5132000.0 41741.0 18334.0 20526.0 20538.0 16927.0 14970.0 11459.0 11781.0 24263.0 18987.0 True False 41145.765685638085 18291.548749437592 18838.431512651307 22048.433032759574 15931.387139762423 14329.767996774428 12052.29095068239 12328.388268654971 21530.24543928314 22268.877651412793 1.8476802616510715 0.8213951792167277 0.8459533438343781 0.9901007755260969 0.7154104211781727 0.6434885592837819 0.5412168111632587 0.5536151602087063 0.9668311881859571 1.0 14.442741227861765 -2.9217278547470538 1.4062668429515703 0.744411229845764 199.99988511429453 0.773958875788251 0.16995218383698046 118.3003355793946 1.7121194576815724 0.05009141072802374 74706.16669123157 0.0011974906889386145 2.9217278547470538 199.25547388444878 KWY(ph)PLRPKK ddPTM_PC-9_Lapatinib_30min_R1 1 KWYPLRPKK 9 3 Q96IY1 Q96IY1 NSL1 Kinetochore-associated protein NSL1 homolog 1 KWY(1)PLRPKK 60.118 0.035229 8736600.0 146570.0 107370.0 110000.0 106780.0 114380.0 110980.0 97515.0 105350.0 102290.0 100140.0 True False 144479.8849223537 107121.39136179331 100956.22461227915 114632.95740763782 107652.39327973206 106233.64410701564 102563.84955544047 110244.9455990835 90769.02303854731 117449.06557183723 1.2301492925372248 0.9120667826537365 0.8595745238222411 0.9760227282312693 0.9165879077504191 0.9045082103444942 0.8732623717019504 0.93866175147773 0.772837336734951 1.0 16.841675709709108 -4.761768217627303 6.801619526990191 0.9035376659050406 1.2378882728509024 0.7249573077146485 0.05991380079800167 0.055188751914773126 13.62994592440411 0.0139730122451194 0.08544057380673124 1.7307398062461674e-05 4.761768217627303 0.33435060694586183 KY(ph)AEHRMLVVAEQPLHAMRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KYAEHRMLVVAEQPLHAMRK 20 3 E7EMW7;O95071-2;O95071;E7ET84 E7EMW7 UBR5 E3 ubiquitin-protein ligase UBR5 1 KY(1)AEHRMLVVAEQPLHAMRK 61.815 0.018147999999999997 0.0 5894.7 3238.6 11220.0 12805.0 9879.2 10805.0 8371.7 9121.2 8721.1 10150.0 True False 6892.556284368029 3560.1068048382404 11487.527352086954 12087.57736437012 7943.441678430589 10238.366778884598 7578.671970140724 8881.778164710251 8848.629588799764 11990.114652644215 0.5748532423622816 0.29692016364940427 0.9580831947719178 1.0081285888041454 0.6624992261169744 0.8539006569571627 0.6320766889805659 0.740758401568039 0.7379937427744571 1.0 13.5495578337987 -5.260584677539561 24.999975929321412 0.8099173253194811 0.4358866939528121 0.5435085166531975 0.14186105649777253 56.562044306477524 1654370.3220347788 0.03710972134563008 0.08724252663872371 5.488015413647027e-06 5.260584677539561 -0.37403063136666903 KY(ph)IFS(ph)VR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KYIFSVR 7 1 E9PIN0;Q13315 E9PIN0 ATM Serine-protein kinase ATM 2 KY(1)IFS(1)VR 81.78399999999999 0.010925 2680200.0 7293.6 7189.1 6768.1 8615.2 8782.8 8034.8 9816.9 7590.6 8389.4 5678.1 True False 8528.262424833609 7902.7863368932885 6929.477172162184 8132.518274855252 7061.873387857331 7613.44094354299 8886.97216379881 7391.354792905497 8512.079103814513 6707.494582185133 1.2714527489122942 1.178202418214814 1.033094710291176 1.2124524552662228 1.0528332600690302 1.1350647921153776 1.324931694675131 1.1019546422797972 1.2690400267220925 1.0 12.711558268846684 KY(ph)IGPCGGR ddPTM_PC-9_Lapatinib_30min_R1 2 KYIGPCGGR 9 1 A0A2R8Y548;P53420 A0A2R8Y548 COL4A4 Collagen alpha-4(IV) chain 1 KY(1)IGPCGGR;KY(1)IGPCGGR 62.54600000000001 0.032167 25538000.0 35148.0 37294.0 40124.0 33575.0 37521.0 34919.0 31137.0 33941.0 36385.0 33862.0 True False 34646.7830746462 37207.64803433655 36825.15960311904 36044.21750291665 35314.08854912423 33425.59577016472 32749.12150548892 35518.02276771228 32286.938148964175 39715.001581721204 0.8723852875431422 0.9368663364591514 0.9272355063953414 0.9075718511240338 0.889187640505534 0.8416365211867151 0.8246033035678306 0.8943225822269493 0.8129658029227981 1.0 15.277396440305104 -6.436473717739108 3.2688859881956223 0.8649731921567088 0.9140120007532062 0.08148138349766565 0.051492385047290264 0.46057001861509206 9.431920255364613 0.016014627156297142 0.017953412166270034 3.660380914669981e-07 6.436473717739108 0.04903880859649745 KY(ph)LVILK ddPTM_PC-9_Lapatinib_30min_R1 3 KYLVILK 7 1 F2Z3H0 F2Z3H0 DNAJC2 1 KY(1)LVILK;KY(1)LVILK;KY(1)LVILK 92.46700000000001 0.013416999999999998 8499700.0 55616.0 59215.0 63111.0 48570.0 51608.4 61848.0 45775.2 39983.3 47504.0 37397.0 True False 54822.90564127472 59077.89130565877 57922.25719550505 52141.99982477028 48572.89537801825 59202.905214729784 48145.21587622625 41841.070084212915 42153.59928070342 43861.021621629785 1.249923134809955 1.3469337722066392 1.3205861389909135 1.1888003949059132 1.1074273599241664 1.3497840001413521 1.0976765724144406 0.9539465460963923 0.9610719888000885 1.0 15.420651795557621 -7.513142110866114 3.7982187967117937 0.9715312646615276 1.2566294811790413 0.7730264233645698 0.07064602895782776 0.11237142197906261 3.593685380624882 0.03670237642240446 0.021695583329998533 3.068017900056534e-08 7.513142110866114 0.28509821651751366 KY(ph)S(ph)LS(ph)S(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 KYSLSSK 7 1 Q8HWS3 Q8HWS3 RFX6 DNA-binding protein RFX6 4 KY(1)S(1)LS(1)S(1)K 59.205 0.022146000000000002 3230000.0 6671.0 6379.9 12399.0 19375.0 12351.0 13173.0 12592.0 18829.0 11544.0 10654.0 True False 8792.239234580098 8442.077909255639 12234.58115863732 14908.393090766021 10636.276843778647 12349.29022757294 13712.663606063732 15919.410697375994 12154.192272456905 10281.006702825214 0.8551924426003921 0.8211333922130175 1.1900178175426406 1.450090786018961 1.034555968225933 1.201175194660593 1.333786077806515 1.5484291721161265 1.1821986526977888 1.0 13.327693917822915 -5.317791902947777 4.349926494556774 1.2682522627472494 0.8343538857036702 0.5038335320837104 0.16021875416148862 0.1546991638932243 6.103337538032966 0.042732184540899026 0.09842494919943319 4.8106980320275515e-06 5.317791902947777 -0.43389837704357925 KYDAFLASESLIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KYDAFLASESLIK 13 1 P62906 P62906 RPL10A 60S ribosomal protein L10a 0 ; 124.42 9.743200000000001e-05 4607000.0 48239.0 44034.0 52741.0 61243.0 70717.0 58851.0 57872.0 56047.0 61915.0 48278.0 False True 56404.9099363207 48405.40450943219 53998.54546135631 57811.753262484934 56860.51149623214 55764.74995873552 52389.94520300345 54575.82563670517 62820.38974332794 57030.41923156228 0.9890320060124088 0.8487646621163754 0.9468376033166518 1.013700303126831 0.9970207524752666 0.9778071196059821 0.9186315988715255 0.9569599237050906 1.1015242495107125 1.0 15.799444017571341 -5.500224851846868 0.29996139823465523 1.0158154890709479 0.8786099277627266 0.17933260598848877 0.056611649481664375 9.341174943938936 0.9648651653163653 0.07193255051455641 0.45513042266670856 3.16064084467694e-06 5.500224851846868 -0.13720556130822126 KYEDICPSTHNMDVPNIK ddPTM_PC-9_Lapatinib_30min_R1 2 KYEDICPSTHNMDVPNIK 18 1 I3L397;I3L504;P63241;P63241-2;F8WCJ1;C9J7B5;C9J4W5;Q9GZV4;Q6IS14 I3L397 EIF5A;EIF5A2;EIF5AL1 Eukaryotic translation initiation factor 5A;Eukaryotic translation initiation factor 5A-1;Eukaryotic translation initiation factor 5A-2;Eukaryotic translation initiation factor 5A-1-like 0 ; 79.32600000000001 0.0014454000000000001 12320000.0 64049.0 62028.0 81152.0 75534.0 89155.0 98739.0 88113.0 66677.0 87147.0 58812.0 False True 63135.64951485189 61884.377976988944 74479.99581577908 81089.02233403747 83911.0781854741 94516.16314185102 92675.05999977987 69775.05683635587 77331.58716140661 68977.57583793583 0.915306876878224 0.8971666113982826 1.0797711417225113 1.1755852731699026 1.2164979294520994 1.370244778736768 1.3435534501462003 1.0115614529610861 1.12111198780164 1.0 16.073839806868904 -5.457555250431577 2.2884256379120895 1.1951089659491079 0.8986658647037093 0.46103166760884606 0.11464269677516724 0.2772945954457643 2.8105497456936583 0.034969675733049196 0.0914307837468006 3.486942208459932e-06 5.457555250431577 -0.2964431012453985 KYEEIDNAPEER ddPTM_PC-9_AZD4547_30min_R2 3 KYEEIDNAPEER 12 1 P49411 P49411 TUFM Elongation factor Tu, mitochondrial 0 ;; 102.33 0.0015447000000000002 12132400.0 62787.0 70953.0 76790.0 109039.0 94806.0 81640.0 68045.0 110305.0 82214.0 85049.0 False True 82751.95994926995 93887.16968846145 75771.71442630529 83901.74318575676 81643.82337068097 76535.03789410557 74100.87317936831 93259.89680673742 86559.66419679242 82071.46039690073 1.0082915492069753 1.1439685517282072 0.9232407229001455 1.0223010871258378 0.9947894551388303 0.9325414403981505 0.9028823518067505 1.1363255430783001 1.0546865351022947 1.0 16.324593004695494 -9.583767233727608 0.001484103106713872 0.03591129583820408 1.9777711269922686 0.0007901876274832853 0.0782973214106291 3115629.812965399 1344.5984583433842 884593.7397904679 874729.3009840952 2.607550729253934e-10 9.583767233727608 1.9418598311540645 KYEEIDNAPEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 KYEEIDNAPEER 12 1 P49411 P49411 TUFM Elongation factor Tu, mitochondrial 0 ;; 110.92 0.00071804 12796600.0 63184.0 65764.0 67078.0 75153.0 82172.0 72848.0 69911.0 72039.0 63865.0 60495.0 False True 73879.80325911565 72292.6153008651 68677.39391473173 70942.42105931352 66070.98647663761 69027.72263842534 63288.52396819142 70148.05258162996 64798.90480429039 71462.26462184337 1.0338295833481512 1.0116194285671705 0.9610301923420937 0.9927256214831603 0.9245576924586036 0.9659324820406843 0.8856215836860908 0.9816097062251271 0.9067569457417358 1.0 16.12489401285319 -5.057737910644522 0.8077334145959242 0.9417967891321614 1.0674856825416439 0.4189963084950472 0.03451771768933947 1.6128133972241558 1.0613413040882445 0.012750636621853141 0.16894558879843155 8.755119724616543e-06 5.057737910644522 0.12568889340948253 KYEEIDNAPEER ddPTM_PC-9_Lapatinib_30min_R1 2 KYEEIDNAPEER 12 1 P49411 P49411 TUFM Elongation factor Tu, mitochondrial 0 ; 84.89200000000001 0.0063038999999999994 9176900.0 69565.0 61869.0 61989.0 56733.0 53268.0 48124.0 41625.0 45422.0 65661.0 47515.0 False True 68572.99034334156 61725.74613172001 56892.503704459785 60905.33407574003 50134.880968917416 46065.84870252321 43780.13882731076 47532.471941163436 58265.56673901705 55727.9044402422 1.2304964816481359 1.1076272605568611 1.0208979554482691 1.0929055145263835 0.8996369318476302 0.8266208673236628 0.7856053312440054 0.852938441138284 1.0455366539306357 1.0 15.766112283718885 -5.716761047626471 1.0081677809488365 0.8843884489398001 1.1934888922354798 0.5890582724474309 0.08640647134304624 0.4684814150455459 0.8808806793165361 0.035142200132252 0.11307561741649198 1.9197246983647536e-06 5.716761047626471 0.30910044329567976 KYEFGESDLR ddPTM_PC-9_Lapatinib_30min_R1 1 KYEFGESDLR 10 1 Q14204;A0A2R8Y706;A0A2R8Y5T0;A0A2R8Y542;A0A2R8Y6I5 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 72.096 0.019903 10919000.0 118940.0 85823.0 91095.0 79498.0 87726.0 95367.0 71513.0 73542.0 95248.0 64891.0 False True 117243.89378907511 85624.28211644937 83605.5207368689 85344.54811755399 82566.12915595194 91288.37572133512 75215.5932242036 76959.02979827039 84520.1672340947 76107.32288817762 1.5405073958696238 1.125046564077083 1.0985213717175177 1.1213710439263298 1.0848644522323307 1.1994690163450186 0.9882832606622598 1.011190866762508 1.11053922312151 1.0 16.215747653070466 -4.754107386808957 3.9208081173055636 1.0816001440328817 1.5978442557500283 0.8377966814814239 0.0608006525169064 0.10492598130465577 2.896646027649975 0.015666805086563738 0.1617453373010151 1.7615404212729155e-05 4.754107386808957 0.5162441117171466 KYELGR ddPTM_PC-9_Lapatinib_30min_R1 1 KYELGR 6 1 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 0 71.378 0.043967 5502300.0 23749.0 28241.0 29437.0 30528.0 31970.0 30214.0 34922.0 35043.0 33517.0 34604.0 False True 23410.334904966796 28175.609699621873 27016.803490106053 32773.13095842262 30089.587455438334 28921.81765227404 36730.090285341685 36671.22571076107 29741.962510343055 40585.255293068345 0.5768187174361598 0.6942326590325539 0.6656802647911474 0.8075132390264901 0.7413920951872738 0.7126188425680217 0.9050106995782506 0.9035603064698287 0.7328267937598204 1.0 15.308668068063263 -3.3079283462501734 0.12330599990861518 1.0680529051863639 1.6838431306305494e-14 0.6832826023627186 0.06884562770878941 34.246137109074816 0.45126075912159147 0.5253322897130355 6.0593540315064836 0.0004921207234190038 3.3079283462501734 -1.068052905186347 KYEQGFITDPVVLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 KYEQGFITDPVVLSPK 16 1 P12268;H0Y4R1 P12268 IMPDH2 Inosine-5-monophosphate dehydrogenase 2 1 KYEQGFITDPVVLS(1)PK;KYEQGFITDPVVLS(1)PK 117.38 6.578899999999999e-05 14521500.0 217050.0 204067.0 199427.0 180857.0 207662.0 249130.0 215611.0 192586.0 203040.0 209330.0 True False 286067.38507953985 270027.66700231534 196782.46767671284 139163.21286279574 178831.7158070411 233551.8617167879 234799.96130614728 162826.25888601938 213772.2798856245 202001.42041509322 1.4161652155301645 1.3367612289430184 0.9741637819790775 0.6889219520181041 0.8852992985869077 1.1561892051890605 1.1623678725805802 0.8060649204912881 1.0582711717885118 1.0 17.624005912060447 -5.235446778168763 4.531932911373502 0.9591920483046436 1.390549581303848 0.5817670568550646 0.13953257487150453 0.1451358136090876 7.613732875905571 0.03939675093558442 0.10544449543608495 5.815046900597997e-06 5.235446778168763 0.43135753299920443 KYEQGFITDPVVLS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KYEQGFITDPVVLSPK 16 1 P12268;H0Y4R1 P12268 IMPDH2 Inosine-5-monophosphate dehydrogenase 2 1 KYEQGFITDPVVLS(1)PK;KYEQGFITDPVVLS(1)PK 119.27 5.1183999999999996e-05 11210400.0 163383.0 180668.0 128886.0 178414.0 172046.0 142529.0 184111.0 145835.0 136571.0 136036.0 True False 191040.51493865752 198603.52504678414 131959.13104287715 168418.04200599235 138334.82134254457 135054.52833203535 166670.67323179022 142006.98577495487 138568.09250805198 160698.2499396162 1.1888151551771269 1.2358785806404935 0.821160971525589 1.0480390549945438 0.8608358920804995 0.8404231432687245 1.0371654532293801 0.8836871952763348 0.8622875019492756 1.0 17.293994692079657 -5.2524469169456 24.995204649075475 0.9189624414294275 1.2123469089922276 0.6896453027245302 0.07866126504777471 337.5623006972149 938274.0595354645 0.019313714682162527 0.049514312010708106 5.591818712151243e-06 5.2524469169456 0.2933844675628001 KYEQGFITDPVVLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 KYEQGFITDPVVLSPK 16 1 P12268;H0Y4R1 P12268 IMPDH2 Inosine-5-monophosphate dehydrogenase 2 1 KYEQGFITDPVVLS(1)PK;KYEQGFITDPVVLS(1)PK 99.34299999999999 0.00088312 12651300.0 204155.0 196767.0 156018.0 184639.0 199873.0 183031.0 187198.0 181725.0 174761.0 181717.0 True False 201243.71226255794 196311.39810082878 143190.80228689592 198217.96799764823 188116.86310543734 175203.19079610016 196890.19647315113 190168.60691972898 155077.57586508515 213126.54132731794 0.9442451935326512 0.9211025378548953 0.6718581430314899 0.9300482556662276 0.8826533848570697 0.8220618122218039 0.9238182877034016 0.8922802656834262 0.7276314573458887 1.0 17.701350742155967 -7.240905240994361 24.62605967011736 0.8769558806831859 0.8600713863524333 0.010966677982920059 0.09641278711947396 6629.885023923615 7951059.9631440835 0.03677571546643844 0.028452623741751785 5.742417427320867e-08 7.240905240994361 -0.016884494330752564 KYEQGFITDPVVLSPK ddPTM_PC-9_Lapatinib_30min_R1 1 KYEQGFITDPVVLSPK 16 1 P12268;H0Y4R1 P12268 IMPDH2 Inosine-5-monophosphate dehydrogenase 2 0 157.91 2.9741999999999997e-05 2013500.0 26201.0 24628.0 26563.0 22942.0 22201.0 23486.0 25402.0 18452.0 24217.0 20041.0 False True 25827.36893532507 24570.97537913981 24379.09267614523 24629.231212268463 20895.18082884536 22481.558528540027 26717.19126705942 19309.34728233778 21489.42644368462 23505.06014704607 1.0988003763338954 1.0453483303350617 1.0371848667321533 1.0478267682868987 0.8889652142188328 0.9564561157426066 1.1366570049137708 0.8214974631649443 0.9142468178872216 1.0 14.52068375179495 -5.386138450077089 0.590194883013464 0.9454468470206678 1.133071485316814 0.26319693446106585 0.08021245512699936 2.9899458680362963 1.2827889411558275 0.048488198879638546 0.3495376570233695 4.110186703072517e-06 5.386138450077089 0.18762463829614617 KYGGSVGSQPPPVAPEPGPVPS(ph)SPSQEPPTKR ddPTM_PC-9_AZD4547_30min_R2 1 KYGGSVGSQPPPVAPEPGPVPSSPSQEPPTKR 32 2 E9PS08;A0A087WTZ5;E9PJ81;E9PRQ7;Q04323;Q04323-2 E9PS08 UBXN1 UBX domain-containing protein 1 1 KYGGSVGSQPPPVAPEPGPVPS(0.476)S(0.476)PS(0.038)QEPPT(0.01)KR 91.67 2.8374e-10 27964000.0 53318.0 59056.0 78326.0 95826.0 87818.0 68665.0 65546.0 79309.0 73837.0 76452.0 True False 70272.01491670548 78144.69709697663 77287.34606270066 73734.79619694155 75625.98654902074 64371.36669523238 71379.46702057276 67053.61638951574 77739.87307877689 73775.43875017788 0.9525123280481479 1.0592237527938553 1.0476026625123163 0.9994491045539701 1.0250835214292562 0.8725311266966497 0.9675234499422161 0.9088880733949422 1.0537365062920678 1.0 16.170852975089126 KYGGSVGSQPPPVAPEPGPVPS(ph)SPSQEPPTKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KYGGSVGSQPPPVAPEPGPVPSSPSQEPPTKR 32 2 E9PS08;A0A087WTZ5;E9PJ81;E9PRQ7;Q04323;Q04323-2 E9PS08 UBXN1 UBX domain-containing protein 1 1 KYGGSVGSQPPPVAPEPGPVPS(0.46)S(0.46)PS(0.075)QEPPT(0.005)KR 64.167 2.675e-05 9448700.0 22698.0 23504.0 23773.0 32088.0 32553.0 38113.0 38093.0 34525.0 31444.0 27164.0 True False 26540.323094065105 25837.321787475466 24339.838479604565 30290.213390699628 26174.47333366578 36114.287185898065 34484.555270562814 33618.75533226126 31903.80901379639 32088.61816989431 0.8270946088593294 0.8051864885760697 0.7585193712841245 0.943955056909183 0.8156933774799562 1.1254547327245352 1.0746662597929002 1.0476847321460083 0.9942406633056169 1.0 14.969774043822817 -6.752302439147119 24.9980837146432 1.0530306368954658 0.8310559390246618 0.7937199054859656 0.05562298497176996 86.87226934703163 237676.6100620606 0.01896577063160123 0.018708028726054746 1.76887669794469e-07 6.752302439147119 -0.22197469787080404 KYGGSVGSQPPPVAPEPGPVPS(ph)SPSQEPPTKR ddPTM_PC-9_Lapatinib_30min_R1 1 KYGGSVGSQPPPVAPEPGPVPSSPSQEPPTKR 32 2 E9PS08;A0A087WTZ5;E9PJ81;E9PRQ7;Q04323;Q04323-2 E9PS08 UBXN1 UBX domain-containing protein 1 1 KYGGSVGSQPPPVAPEPGPVPS(0.472)S(0.472)PS(0.044)QEPPT(0.012)KR 87.352 8.439599999999999e-10 15967000.0 95061.0 64139.0 83573.0 78766.0 75213.0 79294.0 77963.0 79104.0 100190.0 65767.0 True False 93705.41270794762 63990.49008618844 76701.95054110934 84558.7143956735 70789.11921444745 75902.780463342 81999.54266411127 82779.4606233498 88905.5471525277 77134.73832098104 1.214827647667786 0.829593662713998 0.994389197535477 1.0962468562970817 0.9177333164711399 0.9840284950146264 1.0630689161462674 1.073180027899743 1.1526006192250857 1.0 16.235093116686357 -7.386079285152664 4.040408092232803 1.082050896294879 0.9978241964041792 0.08782074487570102 0.10176026412899138 0.5094640407565764 14.181598076053215 0.04359486770054981 0.028280985584841958 4.1107466812922595e-08 7.386079285152664 -0.08422669989069975 KYGGSVGSQPPPVAPEPGPVPSS(ph)PSQEPPTKR ddPTM_PC-9_Lapatinib_30min_R1 1 KYGGSVGSQPPPVAPEPGPVPSSPSQEPPTKR 32 2 E9PS08;A0A087WTZ5;E9PJ81;E9PRQ7;Q04323;Q04323-2 E9PS08 UBXN1 UBX domain-containing protein 1 1 KYGGSVGSQPPPVAPEPGPVPS(0.266)S(0.644)PS(0.079)QEPPT(0.011)KR 90.65899999999999 4.1491e-10 18697000.0 49815.0 32327.0 46972.0 36724.0 36906.0 42185.0 31294.0 37597.0 45628.0 34072.0 True False 49104.62896504785 32252.148817664962 43110.14347716349 39424.80546767272 34735.261639987715 40380.84588803801 32914.25019728203 39343.893874596455 40488.89415585917 39961.29980191376 1.2288045986606324 0.8070845787683912 1.0787973286869645 0.9865746525538354 0.8692225180904709 1.010498809803583 0.8236531434271754 0.984549903772456 1.0132026324609227 1.0 15.28631588928833 -4.741123727741027 24.95083233252911 0.9523139810679302 1.2288056056345957 0.48764641531953223 0.08492776558148601 1241.2770491874203 1524404.0333596398 0.020137641551910675 0.834551416327186 1.8149985075561776e-05 4.741123727741027 0.27649162456666554 KYPS(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 1 KYPSPQK 7 1 Q9P2N5;U3KPZ7 Q9P2N5 RBM27 RNA-binding protein 27 1 KYPS(1)PQK 77.533 0.043562000000000003 35303000.0 70265.0 52087.0 55177.0 57212.0 55556.0 65446.0 54728.0 52121.0 53521.0 47913.0 True False 69263.008214977 51966.39575171574 50640.56004937937 61419.56133363717 52288.305307298455 62647.02714207741 57561.548053839404 54542.73193706527 47492.90137888444 56194.69820994057 1.23255414516533 0.9247562031131815 0.9011625947378306 1.0929778660644598 0.9304846715601527 1.1148209553155932 1.024323466224382 0.9706028090638793 0.845149149150216 1.0 15.778146402752977 -7.966194954987088 4.442092913940503 0.9175081962364294 1.0234581198407435 0.15679885323836296 0.1012053838952806 0.36228059655819883 16.34744546521256 0.060838800994925245 0.026108492792387025 1.0809486040581657e-08 7.966194954987088 0.1059499236043141 KYS(ph)ASSGGLCEEATAAK ddPTM_PC-9_AZD4547_30min_R2 1 KYSASSGGLCEEATAAK 17 1 Q9UHV7;J3QRB7 Q9UHV7 MED13 Mediator of RNA polymerase II transcription subunit 13 1 KY(0.025)S(0.765)AS(0.179)S(0.03)GGLCEEATAAK 67.418 0.0086214 18099000.0 47103.0 40109.0 45336.0 59491.0 58557.0 55422.0 48831.0 55786.0 49213.0 54732.0 True False 62080.77419673606 53073.449875755796 44734.815017983805 45776.269076787656 50427.37131739509 51956.453578725224 53176.86440181843 47165.55553475052 51814.298709669245 52815.849339124274 1.1754194048480184 1.00487733397938 0.8469960358063522 0.8667146254311596 0.9547772486551707 0.9837284494871801 1.0068353546749977 0.8930189729962708 0.9810369303535348 1.0 15.688683307840677 -4.826677856320935 3.532933612481109 0.938753297782244 1.192090148036174 0.632986011948233 0.05347628759832873 0.16907492151462833 3.52857351322945 0.014309035177089157 0.10608951383991173 1.4904662408333582e-05 4.826677856320935 0.25333685025393005 KYS(ph)ASSGGLCEEATAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KYSASSGGLCEEATAAK 17 1 Q9UHV7;J3QRB7 Q9UHV7 MED13 Mediator of RNA polymerase II transcription subunit 13 1 KY(0.226)S(0.258)AS(0.258)S(0.258)GGLCEEATAAK;KY(0.037)S(0.801)AS(0.144)S(0.018)GGLCEEATAAK 84.948 0.0015212 17510000.0 51646.0 55144.0 57857.0 69661.0 76896.0 69353.0 74770.0 78393.0 72745.0 63680.0 True False 60388.6477450034 60618.33188600013 59236.5303038944 65758.12001400926 61828.78080255474 65716.00659102117 67687.24431207795 76335.26681424923 73808.75800498102 75224.67990939728 0.802777064890634 0.8058303732101028 0.7874613806963424 0.8741561957220714 0.8219214874296982 0.8735963605318278 0.8998010279818056 1.0147635976143676 0.9811774286561055 1.0 16.198918442269807 -7.385588240240809 1.0895315026756287 1.0091580266231248 0.8135332429987895 0.8955113689047155 0.02631800893717151 0.15062291357612761 0.33946743822707265 0.019487629639104782 0.010001501507800183 4.115397218939381e-08 7.385588240240809 -0.19562478362433533 KYS(ph)ASSGGLCEEATAAK ddPTM_PC-9_Lapatinib_30min_R1 2 KYSASSGGLCEEATAAK 17 1 Q9UHV7;J3QRB7 Q9UHV7 MED13 Mediator of RNA polymerase II transcription subunit 13 1 KYS(0.652)AS(0.282)S(0.066)GGLCEEATAAK;KYS(0.989)AS(0.009)S(0.002)GGLCEEATAAK 144.56 4.1386000000000007e-05 36071000.0 120394.0 123016.0 122410.0 108199.0 143663.0 140802.0 136522.0 126776.0 152066.0 123787.0 True False 118677.15948244439 122731.1640100804 112345.92231626436 116156.31540128315 135213.02479232536 134780.226685493 143590.44115272374 132666.47577854205 134938.7257540299 145183.41801419042 0.8174291603387153 0.8453524905859738 0.7738206184488887 0.8000659923155266 0.9313255373221029 0.9283444936688251 0.9890278319435145 0.9137853178630568 0.9294362097250033 1.0 17.147517161139618 -6.303175600260039 4.877934343287722 0.9466511071141096 0.8088828874784257 0.8359526895854836 0.030301242571489813 0.08128493528414465 4.695303931343534 0.009553344577620524 0.011144013206142955 4.975358733642405e-07 6.303175600260039 -0.13776821963568386 KYS(ph)DS(ph)S(ph)LPPS(ph)NS(ph)GK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KYSDSSLPPSNSGK 14 1 F8W108;F8WCU9;Q68CP9-3;Q68CP9 F8W108 ARID2 AT-rich interactive domain-containing protein 2 5 KY(0.419)S(0.794)DS(0.794)S(0.994)LPPS(0.999)NS(0.999)GK 40.857 0.046008 0.0 981.86 698.76 1139.8 1058.3 923.39 830.28 674.04 0.0 965.87 704.15 True False 1148.0695053810368 768.1282748560391 1166.9771547155713 999.0068820548931 742.458358110578 786.7386551755945 610.1900515729963 0.0 979.9940215034825 831.806820951667 1.380211698754207 0.9234455110349137 1.402942516605523 1.2010082832837716 0.8925850803448983 0.9458189514189003 0.7335718296645851 0.0 1.1781509802748131 1.0 9.700104705142255 -6.686655963040881 1.4580207487025036 0.663453980109727 1.2172213258415436 0.30523878298418505 0.31834365738056536 0.44229988351564786 1.9577314918012538 0.13669628829684471 0.1318849503245411 2.0575198650764225e-07 6.686655963040881 0.5537673457318166 KYS(ph)SCSTIFLDDSTVSQPNLK ddPTM_PC-9_AZD4547_30min_R2 1 KYSSCSTIFLDDSTVSQPNLK 21 1 Q8ND76-3;Q8ND76-2;Q8ND76;R4GNF3 Q8ND76-3 CCNY Cyclin-Y 1 KY(0.034)S(0.379)S(0.379)CS(0.104)T(0.104)IFLDDSTVSQPNLK 71.06 0.0011635 6714800.0 20117.0 21792.0 35728.0 41739.0 40395.0 28732.0 21707.0 37510.0 29721.0 25443.0 True False 26513.787540405905 28835.83783421354 35254.22337573949 32116.718411121685 34786.851518455085 26935.38349795989 23638.880947968984 31713.69139405032 31291.991383375924 24552.248314246473 1.0798924481804482 1.1744683201774848 1.435885745554438 1.3080968390371777 1.4168499386783233 1.0970638270357749 0.9627990335309737 1.2916817632399233 1.2745061463564096 1.0 14.583567521535253 -6.786084649530023 24.997812654106614 1.1332895283246542 1.2868906555253439 0.24742126273511544 0.13718651394954148 378.4943386972117 383905.7823344311 0.051512476005157924 0.045449384937318545 1.636497516115094e-07 6.786084649530023 0.15360112720068964 KYS(ph)SCSTIFLDDSTVSQPNLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 KYSSCSTIFLDDSTVSQPNLK 21 1 Q8ND76-3;Q8ND76-2;Q8ND76;R4GNF3 Q8ND76-3 CCNY Cyclin-Y 1 KY(0.05)S(0.342)S(0.342)CS(0.133)T(0.133)IFLDDSTVSQPNLK;KY(0.209)S(0.242)S(0.242)CS(0.064)T(0.242)IFLDDSTVSQPNLK 60.621 0.0044678999999999995 12785300.0 65880.0 53926.0 64560.0 67438.0 106775.0 74342.0 62862.0 77708.0 64851.0 58513.0 True False 77032.18281068846 59279.41689548168 66099.35524516353 63659.66749694591 85853.20524075106 70443.37464838862 56907.25627853197 75668.24733843179 65799.32318896167 69120.94371134686 1.1144550215109823 0.857618743503214 0.9562854859331542 0.9209895594422501 1.2420722378918772 1.0191321308135535 0.8232997586980297 1.0947224281894479 0.9519448036436471 1.0 16.07683529436544 KYSAS(ph)SGGLCEEATAAK ddPTM_PC-9_AZD4547_30min_R2 1 KYSASSGGLCEEATAAK 17 1 Q9UHV7;J3QRB7 Q9UHV7 MED13 Mediator of RNA polymerase II transcription subunit 13 1 KYS(0.033)AS(0.93)S(0.036)GGLCEEATAAK 164.69 4.1215e-05 7899800.0 29571.0 31178.0 35178.0 48752.0 39332.0 38769.0 34464.0 43059.0 35117.0 32835.0 True False 38973.96288498993 41255.67878097966 34711.51673510311 37512.97961089158 33871.430719739474 36344.76830128104 37531.22923438535 36405.220947385074 36973.212927223576 31685.456644196154 1.2300268644582977 1.302038321374058 1.09550312387438 1.1839179101041253 1.0689898239463664 1.1470489035207998 1.18449387224659 1.1489568023648302 1.166882754520629 1.0 14.95153318705123 -7.476388490076874 0.020076563317536395 5.21883796977342e-17 2.2813210204476 0.4581802316425049 0.05893729909450226 329.4486544232595 4.915361257731309 272.44294260471327 284.40798878216214 3.338962257184312e-08 7.476388490076874 2.2813210204476 KYSASS(ph)GGLCEEATAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KYSASSGGLCEEATAAK 17 1 Q9UHV7;J3QRB7 Q9UHV7 MED13 Mediator of RNA polymerase II transcription subunit 13 1 KY(0.168)S(0.189)AS(0.1)S(0.543)GGLCEEATAAK 54.658 0.025138999999999998 12686000.0 25795.0 26749.0 23303.0 30006.0 35256.0 31693.0 34995.0 39315.0 34218.0 29093.0 True False 30161.584025526892 29404.463942017588 23858.631897119623 28324.86110076456 28347.839887313647 30030.96328766213 31680.02025814048 38283.022907685794 34718.373515903986 34367.3305999387 0.8776237053913256 0.8555934787111465 0.6942241797843379 0.8241798419111166 0.8248484648779852 0.8738229814018693 0.9218062533549518 1.113936469297795 1.0102144364964416 1.0 15.0687501777307 -7.380598728320765 1.9288278460098904 1.0459423457186632 0.8138328556144219 0.7387480473030649 0.05721168984024167 0.17139202054621566 1.2439244441036084 0.03234217393665671 0.018519158700555243 4.162950737586353e-08 7.380598728320765 -0.2321094901042413 KYSDVEVPASVTGYSFASDGDSGTCS(ph)PLR ddPTM_PC-9_Lapatinib_30min_R1 1 KYSDVEVPASVTGYSFASDGDSGTCSPLR 29 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5 P35611 ADD1 Alpha-adducin 1 KYSDVEVPASVTGYSFAS(0.004)DGDS(0.106)GT(0.258)CS(0.632)PLR 136.56 3.8227e-16 0.0 13666.0 17028.0 17644.0 14346.0 17833.0 15721.0 13861.0 14691.0 14692.0 12239.0 True False 13471.120333962528 16988.57271219721 16193.378427809597 15401.052696853088 16784.09800102696 15048.649477440928 14578.654757606126 15373.597492132263 13037.23224638124 14354.494842557604 0.9384600769108166 1.1835019552084969 1.1281050712979568 1.0729080239865143 1.169257308259025 1.0483579981390445 1.0156160086096475 1.0709953684021862 0.9082334411190146 1.0 13.809214940261004 -7.603750486703211 1.1607661090920267 0.9716944438238245 1.1013686880877565 0.29958144585319024 0.07257963477271967 0.593804692706893 1.4760289636671449 0.056340849618156844 0.024499545771877317 2.4902876413600105e-08 7.603750486703211 0.12967424426393193 KYTELPHGAISEDQAVGPADIPCDSTGQT(ph)ST ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KYTELPHGAISEDQAVGPADIPCDSTGQTST 31 1 Q9H773;H3BPN2;H3BSA6 Q9H773 DCTPP1 dCTP pyrophosphatase 1 1 KYTELPHGAISEDQAVGPADIPCDS(0.007)T(0.018)GQT(0.34)S(0.34)T(0.295) 73.247 0.00063044 0.0 3917.4 4665.2 7073.0 6445.4 7990.0 6736.1 7629.8 7640.6 4442.3 6556.3 True False 4580.538447823184 5128.330224767297 7241.647144501879 6084.285134268741 6424.416856694913 6382.847057773675 6907.050109031581 7440.042345884881 4507.260233494074 7744.9052903577585 0.5914260118230052 0.6621553179161479 0.9350207488679784 0.785585479249636 0.8295023135651736 0.8241349401289882 0.8918185374882132 0.9606369693309967 0.5819645385600153 1.0 12.919031881589568 -5.110735171549603 4.923549589727756 0.8465429858613709 0.6069502924441049 0.40325547988576516 0.11027513183982801 0.19672597846571124 7.063284564536908 0.026615458326731387 0.07719088667807916 7.74934200913512e-06 5.110735171549603 -0.23959269341726597 KYTELPHGAISEDQAVGPADIPCDSTGQT(ph)ST ddPTM_PC-9_Lapatinib_30min_R1 1 KYTELPHGAISEDQAVGPADIPCDSTGQTST 31 1 Q9H773;H3BPN2;H3BSA6 Q9H773 DCTPP1 dCTP pyrophosphatase 1 1 KYTELPHGAISEDQAVGPADIPCDS(0.002)T(0.006)GQT(0.35)S(0.35)T(0.292) 95.323 1.975e-12 13851000.0 22322.0 20421.0 27071.0 24578.0 24183.0 25720.0 18669.0 24384.0 27219.0 21251.0 True False 22003.684186646547 20373.716429162512 24845.326877081923 26385.548109804506 22760.60348560729 24620.01555624836 19635.58947188145 25516.96965816847 24153.309591223184 24924.207034822426 0.8828238409312071 0.8174268654042925 0.9968351989040094 1.0586313968962138 0.9131926826722193 0.9877953397614989 0.7878120031842106 1.0237826071063314 0.9690703322066697 1.0 14.60525998547172 -5.261294506325082 24.999999887349276 0.9636633120944202 0.8501253483648528 0.2984310599408221 0.07160652218160124 15.808537922715601 2727384.458327316 0.018788224353731453 0.043665613006683424 5.479052901602424e-06 5.261294506325082 -0.11353796372956748 KYTELPHGAISEDQAVGPADIPCDSTGQTS(ph)T ddPTM_PC-9_AZD4547_30min_R2 2 KYTELPHGAISEDQAVGPADIPCDSTGQTST 31 1 Q9H773;H3BPN2;H3BSA6 Q9H773 DCTPP1 dCTP pyrophosphatase 1 1 KYTELPHGAISEDQAVGPADIPCDS(0.001)T(0.001)GQT(0.145)S(0.473)T(0.38);KYTELPHGAISEDQAVGPADIPCDS(0.006)T(0.006)GQT(0.146)S(0.445)T(0.397) 122.06 6.5937e-18 36269000.0 102367.0 100661.0 164710.0 217584.0 183427.0 155400.0 120758.0 190892.0 133396.0 150742.0 True False 134917.57663412712 133197.69971685775 162525.83778039803 167423.37043928928 157961.32723049054 145682.8134339056 131505.22806075664 161394.02766177192 140447.04022666844 145464.56846229406 0.9274944274082741 0.9156710883268044 1.117288144449598 1.150956361463975 1.08590929667822 1.0015003307947674 0.9040361474336904 1.1095074860350405 0.9655068702388085 1.0 17.15030826586154 -5.239938267887169 24.38130114480651 1.0448579827406927 0.9215827066778768 0.3054086858397781 0.07242732625597764 754.0173142908218 855017.2741718249 0.01967650304180285 0.05195053435234411 5.755217381645418e-06 5.239938267887169 -0.12327527606281596 KYTELPHGAISEDQAVGPADIPCDSTGQTS(ph)T ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KYTELPHGAISEDQAVGPADIPCDSTGQTST 31 1 Q9H773;H3BPN2;H3BSA6 Q9H773 DCTPP1 dCTP pyrophosphatase 1 1 KYTELPHGAISEDQAVGPADIPCDS(0.07)T(0.07)GQT(0.195)S(0.332)T(0.332) 84.398 3.947e-09 7274500.0 34483.0 40857.0 49201.0 48222.0 51829.0 61326.0 54754.0 51944.0 45115.0 31228.0 True False 40320.29082970514 44913.01294549372 50374.13843583159 45520.27767783336 41673.47950758961 58109.956601747035 49567.30473536859 50580.52503921734 45774.72152580537 36889.389199288016 1.093005108105269 1.2175049226990335 1.365545473352642 1.2339666951902777 1.1296874362016796 1.5752485433634826 1.3436737720863448 1.3711402150348853 1.240864175834303 1.0 15.170918281174933 -4.900290241957656 3.170537604278237 1.3012284500783704 1.0858663748430657 0.12385360737945095 0.1465434126123271 0.5234308750051496 9.092252172696076 0.03671007674093692 0.24202230763558516 1.2580843444512214e-05 4.900290241957656 -0.2153620752353047 KYTELPHGAISEDQAVGPADIPCDSTGQTS(ph)T ddPTM_PC-9_Lapatinib_30min_R1 1 KYTELPHGAISEDQAVGPADIPCDSTGQTST 31 1 Q9H773;H3BPN2;H3BSA6 Q9H773 DCTPP1 dCTP pyrophosphatase 1 1 KYTELPHGAISEDQAVGPADIPCDS(0.069)T(0.069)GQT(0.264)S(0.299)T(0.299) 81.53399999999999 2.0108e-07 14813000.0 62209.0 71897.0 93088.0 75405.0 94420.0 85776.0 78792.0 79687.0 94555.0 69009.0 True False 61321.88825226657 71730.5269138384 85434.66397007121 80950.53524370599 88866.40123686238 82107.5604336221 82871.46422778303 83389.54893169583 83905.22019170829 80937.11370128731 0.7576485674864293 0.8862501222686611 1.0555684538663301 1.000165826798176 1.0979684989118774 1.0144611869488518 1.0238994255915128 1.0303005026774201 1.0366717610091125 1.0 16.30451378152089 -4.991212808305721 2.42186085869379 1.034259703715026 0.7453667843830459 0.9049509968239609 0.028666949157592207 0.09384373065380495 0.9270201582815838 0.007339021911732955 0.04723375474659177 1.0204393364833088e-05 4.991212808305721 -0.28889291933198014 KYTELPHGAISEDQAVGPADIPCDSTGQTST(ph) ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 KYTELPHGAISEDQAVGPADIPCDSTGQTST 31 1 Q9H773;H3BPN2;H3BSA6 Q9H773 DCTPP1 dCTP pyrophosphatase 1 1 KYTELPHGAISEDQAVGPADIPCDS(0.024)T(0.024)GQT(0.303)S(0.303)T(0.346) 79.365 7.022199999999999e-07 6552600.0 33655.0 33476.0 35385.0 39098.0 49953.0 45717.0 43205.0 37050.0 43934.0 28862.0 True False 39352.12678345059 36799.27604482338 36228.71259835977 36907.46581742624 40165.06824061092 43319.52003982111 39112.30962288783 36077.47675771992 44576.451635037876 34094.45212853371 1.1542090963977312 1.0793332565102578 1.0625984679788971 1.082506493381611 1.1780529010758527 1.270573871564486 1.1471751907154026 1.0581626776611734 1.3074400335570069 1.0 15.05724938161956 -6.260844744619011 24.28445030382874 1.1680062898299024 1.0912766875839646 0.1156455687486323 0.08705800988940043 70.64739712781403 2885160.7933790637 0.025495797978938077 0.031011227417865238 5.484730027930448e-07 6.260844744619011 -0.07672960224593783 KYTLENKEEGSLS(ph)DTEADAVSGQLPDPTTNPSAGK ddPTM_PC-9_Lapatinib_30min_R1 1 KYTLENKEEGSLSDTEADAVSGQLPDPTTNPSAGK 35 2 Q8N1G4 Q8N1G4 LRRC47 Leucine-rich repeat-containing protein 47 1 KY(0.013)T(0.013)LENKEEGS(0.078)LS(0.666)DT(0.224)EADAVS(0.005)GQLPDPTTNPSAGK 59.218999999999994 0.00013330000000000001 19604000.0 30323.0 37178.0 40906.0 37067.0 38334.0 36147.0 34658.0 32337.0 39460.0 29246.0 True False 29890.58845944284 37091.916625209495 37542.86658172633 39793.03083188716 36079.269487543745 34601.07707277255 36452.4216571036 33839.4950720224 35015.59926777862 34301.13213215454 0.8714169650226451 1.081361293915976 1.094508089035724 1.1601083800550247 1.05183902818538 1.0087444618289094 1.0627177411130522 0.9865416377991969 1.0208292581385185 1.0 15.065968573862705 -7.484852466727863 1.336295968587209 1.0031802728262296 1.0576272738525117 0.05199462107403985 0.07128533483790066 1.287178158049284 4.372907698809684 0.052657000136518375 0.025295215065589027 3.274519139931197e-08 7.484852466727863 0.05444700102628208 LAAAEETAVS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 5 LAAAEETAVSPR 12 0 Q9BUH6 Q9BUH6 C9orf142 Protein PAXX 1 LAAAEETAVS(1)PR;LAAAEETAVS(1)PR;LAAAEETAVS(1)PR;LAAAEET(0.001)AVS(0.999)PR;LAAAEETAVS(1)PR 143.55 7.5475e-05 232486400.0 141994.0 141085.0 129694.0 165562.0 168539.0 151851.0 150832.0 150071.0 136076.0 149327.0 True False 187145.1383413233 186687.96718245282 127974.1728194457 127394.23880740134 145140.2690449044 142355.73296494156 164255.7557996989 126880.97523851017 143268.69955534025 144099.10718160117 1.298725176037859 1.2955525598585351 0.8880983048574063 0.8840737552027474 1.0072253179333797 0.9879015612882145 1.1398804545866845 0.8805118763061328 0.9942372465554946 1.0 17.136701871235616 -5.251875670040715 24.853181621911293 0.9730492327989315 1.2971389311835058 0.7568317030522854 0.07355136248130971 296.0633433722969 769374.5297669946 0.01951952695985588 0.050220430316356986 5.599178720153257e-06 5.251875670040715 0.32408969838457424 LAAAEETAVS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LAAAEETAVSPR 12 0 Q9BUH6 Q9BUH6 C9orf142 Protein PAXX 1 LAAAEET(0.001)AVS(0.999)PR;LAAAEETAVS(1)PR;LAAAEETAVS(1)PR;LAAAEETAVS(1)PR;LAAAEET(0.129)AVS(0.871)PR;LAAAEETAVS(1)PR 161.25 0.00014222 213593000.0 195924.4 214941.7 173968.0 219540.9 211427.0 188230.6 224750.0 202689.0 180467.4 156220.1 True False 229090.53123670976 236279.69147579244 178116.0568973141 207240.73513420124 169999.39709141917 178359.45597496655 203460.0529509091 197368.6285167473 183106.394314222 184541.5674923684 1.241403410351891 1.2803602715987747 0.9651812289102831 1.123003006586966 0.9211984020806011 0.9665001679491125 1.1025161198943596 1.0695077060343565 0.9922230357222594 1.0 17.493586290509164 -5.256035579504557 24.966695294490222 1.021539798615001 1.2608818689224377 0.7161461834682056 0.06124473543398824 224.8442260166818 1038819.1843839672 0.01589860151913733 0.039551790545208874 5.545802771980705e-06 5.256035579504557 0.2393420703074367 LAAAEETAVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 5 LAAAEETAVSPR 12 0 Q9BUH6 Q9BUH6 C9orf142 Protein PAXX 1 LAAAEET(0.001)AVS(0.999)PR;LAAAEET(0.01)AVS(0.99)PR;LAAAEETAVS(1)PR;LAAAEET(0.015)AVS(0.985)PR;LAAAEET(0.001)AVS(0.999)PR 158.86 0.00049548 225484000.0 153605.0 150432.0 132417.6 135706.6 153776.0 135909.0 118759.6 122189.2 144806.0 127119.40000000001 True False 151414.56453229277 150083.68394651433 121530.73607471757 145686.9160679467 144731.19801524832 130096.4888893529 124908.39099281433 127866.5563056054 128496.42340521922 149091.81891404683 1.0155792962696701 1.0066527126685558 0.8151402066184561 0.9771623763738297 0.9707521114802922 0.8725930761120773 0.8377950708672047 0.857636302494384 0.8618609950643831 1.0 17.185841569509847 -6.768706076447671 24.92165647270131 0.8740679644618885 0.9530453021067393 0.21094699538766837 0.06655300324749591 238.37333059523786 817512.5024913506 0.0233154737198583 0.02098176485824929 1.7033108919353766e-07 6.768706076447671 0.07897733764485082 LAAELEDRR ddPTM_PC-9_AZD4547_30min_R2 1 LAAELEDRR 9 1 Q9NQG5;A0A087X2D2;A2A2M0 Q9NQG5 RPRD1B Regulation of nuclear pre-mRNA domain-containing protein 1B 0 90.709 0.01661 0.0 7367.2 7664.2 11142.0 13447.0 13292.0 9528.9 8846.7 11696.0 8727.2 9907.0 False True 9709.816352720503 10141.502768400294 10994.249799946534 10347.001904078994 11446.635236620994 8933.05637664312 9634.03916167122 9888.65194734238 9188.501975068084 9560.15894545611 1.0156542802392972 1.0608090123041827 1.1500070095771826 1.0823043804095815 1.1973268752044666 0.9344045875815644 1.007727927604198 1.0343606213830159 0.9611243942168269 1.0 13.222818889051695 -6.774778079417569 24.99997553605169 0.9909338272761815 1.1006347418110403 0.541937219005296 0.05221597449615088 195.51820090812564 366446.69168300316 0.01865683771490114 0.01654718135593076 1.6796620911235747e-07 6.774778079417569 0.10970091453485875 LAAGRPFNT(ph)YPR ddPTM_PC-9_AZD4547_30min_R2 1 LAAGRPFNTYPR 12 1 O96013 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 LAAGRPFNT(0.866)Y(0.134)PR 68.786 0.024285 16605000.0 14671.0 14718.0 14919.0 40737.0 31448.0 18149.0 25109.0 36729.0 19471.0 25952.0 True False 19336.072824242925 19475.305673823186 14721.164312098575 31345.714030376 27081.988031993442 17014.140160952047 27343.652357421703 31053.37699845574 20500.197309165676 25043.428379174024 0.7721016680097481 0.7776613241188153 0.5878254402396684 1.2516542685682333 1.0814009816050056 0.6793854221293804 1.0918494042996338 1.2399810652234642 0.8185858980160051 1.0 14.612144456479038 -5.750098267943879 24.999256712900742 1.0242161825877512 0.7190426608243419 0.41018437566801624 0.17069710685675005 227.9915642502151 502558.08904015657 0.047479541319204635 0.08130712862322961 1.7778770837375005e-06 5.750098267943879 -0.3051735217634093 LAAGRPFNT(ph)YPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LAAGRPFNTYPR 12 1 O96013 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 LAAGRPFNT(0.999)Y(0.001)PR 114.72 0.007785899999999999 9569200.0 17747.0 19761.0 22878.0 28128.0 30836.0 25386.0 26951.0 24268.0 26447.0 27910.0 True False 20751.216580772463 21722.741484100698 23423.498285298152 26552.07935220641 24793.90715807816 24054.713470501094 24398.006171657216 23630.990714071428 26833.7373421916 32969.86206456158 0.6293995570905766 0.658866617080873 0.7104518132174851 0.8053439623196521 0.752017315375076 0.7295970308701066 0.740009349262094 0.7167452101497187 0.8138868548993556 1.0 15.008860230792228 -14.522878745277211 0.14572648805950925 1.956223671585227 0.6396789388107033 0.8151871580503525 0.041982233765289215 63.9367341149925 0.5588765359046138 17.688434119026805 0.25954967408800994 3.0000000000215973e-15 14.522878745277211 -1.3165447327745237 LAAGRPFNT(ph)YPR ddPTM_PC-9_Lapatinib_30min_R1 4 LAAGRPFNTYPR 12 1 O96013 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 LAAGRPFNT(1)YPR;LAAGRPFNT(0.989)Y(0.011)PR;LAAGRPFNT(0.998)Y(0.002)PR;LAAGRPFNT(0.99)Y(0.01)PR 145.29 0.0011145999999999999 174466000.0 154931.0 139441.0 148897.0 136558.0 130364.0 121901.0 111449.0 118598.0 136024.0 89408.0 True False 152721.65552913395 139118.1329317293 136655.26341904112 146600.9308641336 122696.24582548528 116687.5783951101 117219.28389585477 124108.49604328534 120703.54472377911 104862.05367132847 1.4564053457107842 1.326677554568695 1.3031907981447972 1.398036045752339 1.1700728865186536 1.1127722022386348 1.1178427256751793 1.1835405821087717 1.1510698150362666 1.0 16.678133180147455 -6.352619685012705 4.274044415435109 1.126513747189447 1.363108438414043 0.8075370159485451 0.05963078072377751 0.10283432090089635 3.3398341919830754 0.018610518372843554 0.02137113109425706 4.43997285544768e-07 6.352619685012705 0.23659469122459598 LAAIAESGVER ddPTM_PC-9_Lapatinib_30min_R1 1 LAAIAESGVER 11 0 P28072 P28072 PSMB6 Proteasome subunit beta type-6 0 113.18 0.0073531000000000004 2878600.0 19999.0 20355.0 25344.0 16379.0 20369.0 23535.0 18710.0 19387.0 20677.0 17349.0 False True 19713.810592632577 20307.86924810747 23260.314150669154 17583.566298742273 19170.935466994786 22528.462912764593 19678.712251266894 20287.790795723107 18348.138521537217 20347.75153391061 0.968844668649431 0.9980399659521754 1.143139285532586 0.8641527919897353 0.9421648104482405 1.1071721057346169 0.967119743843504 0.997053200787931 0.9017280602703974 1.0 14.312581762242639 -8.054716508328042 22.868338024848004 0.9503726063160846 0.9996693906035025 0.056313110609689576 0.07788031704338261 392.5241792656303 164046.84804789667 0.05264871470994677 0.019899869926603902 8.816241774768436e-09 8.054716508328042 0.049296784287417905 LAAIVAK ddPTM_PC-9_Lapatinib_30min_R1 1 LAAIVAK 7 0 P40429;M0QYS1;M0QZU1;A0A096LPE0 P40429 RPL13A 60S ribosomal protein L13a 0 109.88 0.043988 5475900.0 70342.0 72221.0 69677.0 66494.0 74754.0 64982.0 64875.0 63425.0 61665.0 72216.0 False True 69338.91018085688 72053.77671174487 63948.42602099794 71384.19057748141 70357.11669201875 62202.871340440564 68233.91006418712 66371.95704434611 54719.63833876253 84698.43937822875 0.8186562903622998 0.8507096144945722 0.7550130379077034 0.8428040835405322 0.8306778402118191 0.7344039842654935 0.8056100037390566 0.7836266822810746 0.6460524980207357 1.0 16.37004776679249 -6.7048925627706275 24.99976532795078 0.781143696759882 0.8190061176961297 0.010885243886262996 0.0864523135829882 310.9932963386669 137490.52756143536 0.026837271956491708 0.026837254395416683 1.9729107410438103e-07 6.7048925627706275 0.0378624209362477 LAALALASSENSS(ph)STPEECEEMSEKPK ddPTM_PC-9_Lapatinib_30min_R1 1 LAALALASSENSSSTPEECEEMSEKPK 27 1 O00567 O00567 NOP56 Nucleolar protein 56 1 LAALALAS(0.002)S(0.008)ENS(0.023)S(0.441)S(0.441)T(0.083)PEECEEMSEKPK 97.352 1.177e-09 4307700.0 17420.0 21167.0 25253.0 20376.0 24141.0 20952.0 24367.0 21835.0 21340.0 21096.0 True False 17171.58760556324 21117.989111996605 23176.795819398987 21874.519012343404 22721.073843032114 20055.931801497518 25628.604031353323 22849.533812586476 18936.464479837705 24742.415491346947 0.6940141964542056 0.8535136401448801 0.9367232486862288 0.8840898747332685 0.9183045952396303 0.810589079651968 1.035816573378468 0.9234964880683352 0.7653442117023809 1.0 14.594698730602554 -4.790203147825487 2.9026486766356276 0.906839409277724 0.6593047052381893 0.4257885953245115 0.07519877918072465 0.37725265398127966 4.5563037219716325 0.018735065469486358 0.22086425205343857 1.6210516485097423e-05 4.790203147825487 -0.2475347040395347 LAALALASSENSSST(ph)PEECEEMSEKPK ddPTM_PC-9_AZD4547_30min_R2 1 LAALALASSENSSSTPEECEEMSEKPK 27 1 O00567 O00567 NOP56 Nucleolar protein 56 1 LAALALAS(0.002)S(0.01)ENS(0.009)S(0.279)S(0.279)T(0.414)PEECEEMS(0.007)EKPK 69.27199999999999 0.00015775 7938900.0 34395.0 39088.0 40609.0 48330.0 39425.0 44299.0 34632.0 37171.0 34821.0 37136.0 True False 45331.894539556655 51722.43159249901 40070.49812655075 37188.26519105661 33951.519275036284 41528.976527082166 37714.18090892622 31427.076054605324 36661.56697151957 35835.87994331867 1.2649862264093348 1.443314121888676 1.1181669932461529 1.0377383016651747 0.9474169276361326 1.1588658236596456 1.0524139763995872 0.876972355759459 1.0230407912267503 1.0 15.129117159606247 -5.4459172525487665 3.6546198735812765 1.0156470593232367 1.352300090215997 0.7373085532199395 0.0799574357226502 0.11547236997083074 2.9169189158161166 0.022168543757670845 0.04895188823320232 3.581646728085375e-06 5.4459172525487665 0.3366530308927602 LAALALASSENSSST(ph)PEECEEMSEKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LAALALASSENSSSTPEECEEMSEKPK 27 1 O00567 O00567 NOP56 Nucleolar protein 56 1 LAALALAS(0.003)S(0.008)ENS(0.005)S(0.005)S(0.016)T(0.946)PEECEEMS(0.016)EKPK;LAALALASSENSS(0.002)S(0.036)T(0.961)PEECEEMSEKPK 103.57 5.2078e-10 17360500.0 74857.0 76731.0 59745.0 80513.0 89848.0 84947.0 83624.0 94687.0 76820.0 71153.0 True False 87528.81160685649 84348.34658248723 61169.54738417427 76002.11763666772 72242.92937926465 80492.229779353 75702.52933466905 92201.56657916917 77943.34717083839 84052.4756531618 1.0413591143708794 1.0035200739422159 0.7277542619516318 0.9042222379063115 0.8594979364721078 0.9576425816593437 0.9006579371564452 1.0969524200528509 0.9273176853525121 1.0 16.359002692287994 -7.723824602532509 24.992918336647083 1.0091014387533939 0.9090999216179987 0.1915083130409051 0.08871017126131266 257.84589766473766 171324.1161342193 0.04294053550975973 0.024791040479200575 1.8887540016148874e-08 7.723824602532509 -0.10000151713539518 LAALALASSENSSST(ph)PEECEEMSEKPK ddPTM_PC-9_Lapatinib_30min_R1 2 LAALALASSENSSSTPEECEEMSEKPK 27 1 O00567 O00567 NOP56 Nucleolar protein 56 1 LAALALAS(0.009)S(0.027)ENS(0.072)S(0.258)S(0.258)T(0.347)PEECEEMS(0.029)EKPK;LAALALAS(0.003)S(0.014)ENS(0.047)S(0.184)S(0.148)T(0.603)PEECEEMS(0.001)EKPK 71.656 0.00010952 8003900.0 18230.4 19645.0 21042.0 19320.5 17185.9 19331.800000000003 19386.6 19834.2 19942.2 17280.5 True False 17970.431152954097 19599.51320948519 19312.007984468924 20741.39402129863 16175.05915077941 18505.02397862684 20390.34328863768 20755.769340306975 17696.09943532426 20267.411400181125 0.8866663234947458 0.9670457081317269 0.9528601163292287 1.0233864410091005 0.7980821443548957 0.9130432897050417 1.006065495293368 1.024095723448999 0.8731307163955884 1.0 14.306874215833066 -7.250470615061484 24.440249860507336 0.9778309612165175 0.9256648390135993 0.12822178364459125 0.06659596756418912 1223.999080142475 2727278.9934913954 0.02620063810723596 0.02007438060606948 5.617322846184897e-08 7.250470615061484 -0.052166122202918164 LAAPSVSHVS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 LAAPSVSHVSPR 12 0 A0A0U1RRM7;A0A0U1RQW3;A0A0U1RQJ8;Q8WXE1-5;Q8WXE1-3;Q8WXE1-2;Q8WXE1 A0A0U1RRM7 ATRIP ATR-interacting protein 1 LAAPSVSHVS(1)PR;LAAPSVS(0.012)HVS(0.988)PR;LAAPS(0.001)VS(0.003)HVS(0.997)PR 137.39 3.7561e-05 91022000.0 36380.1 37753.1 156955.0 259673.0 189726.0 157783.0 97259.0 217090.0 114672.0 145756.0 True False 47948.215046911595 49956.05127289129 154873.674147425 199809.4017578574 163385.81980914503 147916.80406719382 105914.8625843511 183543.72873192187 120733.32781247221 140653.12680467387 0.3408969010230229 0.35517199231742397 1.101103670183595 1.420582722169656 1.1616223792595826 1.0516424869289047 0.7530217421432509 1.3049388442448957 0.8583764225884261 1.0 17.101782099435354 -5.260122710596009 12.32335390069639 1.0945179681194457 0.3478743587035615 0.7174299799388968 0.18395576587891146 0.06963361809486648 527.4387329187227 0.04871479057484662 0.11430121212735916 5.4938562214477056e-06 5.260122710596009 -0.7466436094158841 LAAPSVSHVS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LAAPSVSHVSPR 12 0 A0A0U1RRM7;A0A0U1RQW3;A0A0U1RQJ8;Q8WXE1-5;Q8WXE1-3;Q8WXE1-2;Q8WXE1 A0A0U1RRM7 ATRIP ATR-interacting protein 1 LAAPS(0.003)VS(0.003)HVS(0.995)PR;LAAPSVS(0.007)HVS(0.993)PR;LAAPSVS(0.009)HVS(0.991)PR;LAAPS(0.001)VS(0.072)HVS(0.927)PR;LAAPSVS(0.071)HVS(0.929)PR 125.39 0.00016688 45333800.0 53742.50000000001 66140.0 162754.0 148256.0 186859.0 181908.0 150850.0 137980.5 146708.0 97014.59999999999 True False 62840.04378724095 72705.9420959677 166634.67260798256 139949.69697243682 150245.32032855478 172368.42424926776 136560.3959405772 134358.65807742433 148853.32695573248 114602.57901284902 0.5483301015433121 0.6344180272576243 1.4540220127969354 1.2211740623807945 1.3110116859735728 1.504053623696742 1.1915996753028246 1.1723877353786278 1.2988654202890437 1.0 16.806279985260964 -5.2487143526827 22.172981587088923 1.2806988854324355 0.5913732160095992 0.7970384647136584 0.13670689852321957 66.53004217650164 115923.48350196274 0.03382995419597088 0.0877764787238372 5.6400849761695685e-06 5.2487143526827 -0.6893256694228362 LAAPSVSHVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 LAAPSVSHVSPR 12 0 A0A0U1RRM7;A0A0U1RQW3;A0A0U1RQJ8;Q8WXE1-5;Q8WXE1-3;Q8WXE1-2;Q8WXE1 A0A0U1RRM7 ATRIP ATR-interacting protein 1 LAAPSVS(0.001)HVS(0.999)PR;LAAPSVS(0.001)HVS(0.999)PR 125.39 0.00016688 51111000.0 58055.0 36868.0 113374.0 55076.0 73305.0 82904.0 55439.0 61906.0 106667.0 44504.0 True False 57227.125054016906 36782.634411163184 104052.82735629573 59126.47276815004 68993.34402317513 79358.38917866307 58309.360154889706 64782.378758964005 94653.03920669405 52196.45710214751 1.0963794907003834 0.704695997645592 1.9934844840650057 1.1327679319774637 1.3218012841016473 1.5203788453181823 1.117113371138952 1.241125975891162 1.813399691505111 1.0 15.671664264991605 -5.217115548951107 24.999920320129707 1.3840507352050557 0.9005376488361879 0.28772755993009236 0.30939297433707075 555.5171563201949 313325.9568012823 0.07430052161904463 0.1965786032917473 6.065749220096576e-06 5.217115548951107 -0.4835130863688678 LAAQESS(ph)EAEDMSVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LAAQESSEAEDMSVPR 16 0 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;Q5SRD0 J3KP36 FAM21C;FAM21D WASH complex subunit FAM21C;Putative WASH complex subunit FAM21 1 LAAQES(0.345)S(0.649)EAEDMS(0.007)VPR 88.319 0.020526 0.0 9817.2 11584.0 12962.0 11653.0 12540.0 8882.0 9989.2 10336.0 8782.6 8741.0 True False 11479.058061461634 12733.982964011051 13271.063238658748 11000.12018953573 10082.877019143209 8416.212284132624 9042.950660454837 10064.690951897242 8911.028909953196 10325.67410628207 1.111700596329866 1.2332350249427089 1.2852490890240982 1.0653173900620525 0.9764860788128937 0.8150763037361656 0.8757733942961814 0.9747248313573981 0.8629973034430544 1.0 13.333948349866706 -6.126232716389051 2.395216426999838 0.9045751021847096 1.2105482562719876 0.7881489380663955 0.06797047845607392 0.12603824484698908 1.4167109241970306 0.021731841655233983 0.03039543560592791 7.47768701810199e-07 6.126232716389051 0.305973154087278 LAAQESS(ph)EAEDMSVPR ddPTM_PC-9_Lapatinib_30min_R1 3 LAAQESSEAEDMSVPR 16 0 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;Q5SRD0 J3KP36 FAM21C;FAM21D WASH complex subunit FAM21C;Putative WASH complex subunit FAM21 1 LAAQES(0.2)S(0.8)EAEDMSVPR;LAAQES(0.226)S(0.774)EAEDMS(0.001)VPR;LAAQES(0.285)S(0.715)EAEDMSVPR 109.42 0.0038409 0.0 22349.2 26471.8 28682.1 23473.4 24591.1 24054.5 23206.999999999996 21583.9 22478.9 18866.699999999997 True False 22030.496309658673 26410.506173522557 26323.96845410778 25199.712140966898 23144.699845962776 23025.745108778257 24408.544907276908 22586.766789900852 19947.08956868903 22127.783956702468 0.9956033714341138 1.1935450122434361 1.189634194983827 1.1388267433501378 1.0459565174375396 1.0405807085713072 1.1030722712693335 1.020742376827995 0.9014499421957295 1.0 14.43357135555236 -7.427197569549117 0.774331646175485 0.9594159200118676 1.130500602095583 0.43745872379756556 0.06608002294074872 0.6251249785642947 0.7135854611495758 0.05875247521019765 0.032322163185040935 3.739404363276284e-08 7.427197569549117 0.1710846820837154 LAAQESS(ph)ETEDMSVPR ddPTM_PC-9_Lapatinib_30min_R1 1 LAAQESSETEDMSVPR 16 0 E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 E7ESD2 FAM21A WASH complex subunit FAM21A 1 LAAQES(0.081)S(0.916)ET(0.003)EDMSVPR 205.98 5.7207e-17 2789100.0 5940.8 9953.9 9610.0 6461.9 9088.1 7393.9 7937.3 9310.6 7911.1 7023.5 True False 5856.083102590708 9930.85235611579 8819.902895672765 6937.129682266483 8553.555825892057 7077.6801330227345 8348.254556492826 9743.204466016377 7020.0686104238075 8237.502616774522 0.7109051583990534 1.2055659121604403 1.0707010736132898 0.8421399063521982 1.038367600451372 0.8592021711301225 1.0134448442532538 1.1827862058794014 0.8522083618071841 1.0 13.007991303078015 -7.504847593906969 24.620633453584595 1.030121464676868 0.967086125089642 0.026371620394641027 0.14880719268271375 2514.0584822343617 3432834.8053879323 0.06169351380657674 0.040672106297860375 3.1271765884090955e-08 7.504847593906969 -0.06303533958722596 LAAQESSETEDMS(ph)VPR ddPTM_PC-9_Lapatinib_30min_R1 1 LAAQESSETEDMSVPR 16 0 E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 E7ESD2 FAM21A WASH complex subunit FAM21A 1 LAAQES(0.018)S(0.062)ET(0.113)EDMS(0.806)VPR 109.55 0.00067021 2484800.0 7588.1 8221.0 7705.6 10024.0 10128.0 10823.0 10579.0 7788.8 9878.8 9421.2 True False 7479.89230251289 8201.964779596734 7072.075312476175 10761.198399083738 9532.290952414125 10360.12551964526 11126.728856555454 8150.6960824123435 8766.145515624217 11049.641867040087 0.676935270166956 0.7422833136395423 0.6400275590443729 0.9738956726899226 0.862678724533864 0.9375983080997782 1.00697642425365 0.737643462158263 0.7933420486479931 1.0 13.431711990340977 -5.756815130267596 24.999776915067674 0.8950542055462115 0.692002147537862 0.569819983392718 0.08555377143980009 92.20781227661742 498489.0409309183 0.024378612060139315 0.04049389607967054 1.7505917189311588e-06 5.756815130267596 -0.20305205800834947 LAAQLGAPT(ph)SPIPDSAIVNTR ddPTM_PC-9_AZD4547_30min_R2 2 LAAQLGAPTSPIPDSAIVNTR 21 0 B8ZZS4;Q9H8Y5 B8ZZS4 ANKZF1 Ankyrin repeat and zinc finger domain-containing protein 1 1 LAAQLGAPT(0.472)S(0.472)PIPDS(0.053)AIVNT(0.003)R;LAAQLGAPT(0.853)S(0.147)PIPDSAIVNTR 246.67 6.512699999999998e-61 18026800.0 35022.0 35614.0 54275.0 65590.0 53594.0 58634.0 50380.0 67600.0 47794.0 46706.0 True False 46158.267497146444 47125.52903027169 53555.278037345015 50469.23885539829 46153.39819977922 54967.606710962726 54863.722401007835 57153.97329346314 50320.29326661514 45070.83715619996 1.0241271387344733 1.0455880565730535 1.1882468002921915 1.119775935833837 1.0240191021930096 1.2195825544678476 1.2172776425445375 1.2680921167580537 1.1164712359839772 1.0 15.45990662680444 -6.77142902921657 24.99983755116906 1.184352529869392 1.0866045456258107 0.18278367100247928 0.08298523226179826 299.7844918000362 750228.1894779366 0.02873496023107779 0.025631618111208527 1.6926648308060107e-07 6.77142902921657 -0.09774798424358133 LAAQLGAPTS(ph)PIPDSAIVNTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LAAQLGAPTSPIPDSAIVNTR 21 0 B8ZZS4;Q9H8Y5 B8ZZS4 ANKZF1 Ankyrin repeat and zinc finger domain-containing protein 1 1 LAAQLGAPT(0.016)S(0.984)PIPDSAIVNTR;LAAQLGAPT(0.418)S(0.582)PIPDSAIVNTR 204.05 1.9764e-24 8389700.0 31532.0 31875.0 31877.0 35133.0 44639.0 35356.8 45269.0 32700.0 29525.0 35080.9 True False 36869.74481461192 35039.33934546378 32637.0685741957 33164.61191272282 35892.308393742715 33502.62716591088 40980.79260082187 31841.65964851391 29956.747269187723 41440.78946974841 0.8896969697338095 0.8455277950494244 0.7875590448879024 0.8002890952869719 0.866110632857126 0.8084456786318622 0.9888999009234046 0.7683651797164284 0.7228807088980777 1.0 15.33876386696682 -6.287273875182434 23.693707011579928 0.8514908465314615 0.8287360843098468 0.02097836207166548 0.08541443573189712 2562.5826460900134 2350225.9288014187 0.026750731488245375 0.030348259852676602 5.160908089734507e-07 6.287273875182434 -0.022754762221614655 LAAQLGAPTS(ph)PIPDSAIVNTR ddPTM_PC-9_Lapatinib_30min_R1 2 LAAQLGAPTSPIPDSAIVNTR 21 0 B8ZZS4;Q9H8Y5 B8ZZS4 ANKZF1 Ankyrin repeat and zinc finger domain-containing protein 1 1 LAAQLGAPT(0.007)S(0.993)PIPDSAIVNTR;LAAQLGAPT(0.044)S(0.956)PIPDSAIVNTR 181.51 3.534e-13 9754700.0 25369.0 41579.0 48591.0 35943.0 49034.0 54700.0 51959.0 48123.0 60178.0 43904.0 True False 25007.23340789516 41482.726380106134 44596.03554668422 38586.368122333115 46149.91652455311 52360.608511927894 54649.182782660435 50358.97026164866 53400.119937566735 51492.7479015973 0.4856457351175745 0.8056032756181447 0.8660643947747224 0.7493553887640976 0.8962410903520949 1.0168540356787537 1.061298629606932 0.9779817996484613 1.037041566311715 1.0 15.652081640910806 -4.267272569314673 0.43609221853928487 1.032942216605577 2.4806197794302702e-17 0.8136723714401821 0.07196039373766379 3.6579497836239487 0.38672155021344756 0.054863152721052195 2.143759302563201 5.404150444190116e-05 4.267272569314673 -1.032942216605577 down LAAVDATVNQVLASR ddPTM_PC-9_Lapatinib_30min_R1 1 LAAVDATVNQVLASR 15 0 Q15084-3;Q15084;Q15084-4;Q15084-5;Q15084-2 Q15084-3 PDIA6 Protein disulfide-isomerase A6 0 82.774 0.034332 1488200.0 8502.0 7519.7 8068.4 6526.8 8340.0 7443.4 5947.9 6581.2 7301.0 4907.0 False True 8380.759920924147 7502.288596658993 7405.047296924677 7006.802644766541 7849.457597070873 7125.063133412873 6255.853158701784 6886.986577851805 6478.684497061626 5755.168411833496 1.4562145399067798 1.3035741197830377 1.2866777767439055 1.2174800359203208 1.3638971156658426 1.238028607253728 1.0869974101607183 1.1966611721893523 1.1257158841330293 1.0 12.49064243080622 -1.5228787452866905 0.09237373620085888 0.831568136461483 2.441234899920751 0.7721317536937768 0.06098639907786278 73.50034312911983 0.48843864372628015 1.0776742852948438 14.982307570710883 0.029999999999561152 1.5228787452866905 1.609666763459268 LADALQELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LADALQELR 9 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ; 96.03399999999999 0.024118999999999998 6530700.0 27703.0 30372.0 27816.0 33884.0 35494.0 27641.0 32435.0 27211.0 30527.0 25200.0 False True 32392.570740809144 33387.131438444725 28479.238932767443 31985.589333410167 28539.205495810922 26191.45730080048 29362.521990935446 26496.740082437707 30973.399623589947 29768.56051690976 1.0881470309056038 1.1215567988072337 0.9566884806737654 1.07447551302459 0.9587029066991494 0.8798362045730314 0.9863601558515512 0.8900914126293232 1.0404735427497673 1.0 14.861501840113439 -5.43350701505236 0.9569854050518972 0.954576484774178 1.1258187789455112 0.4076893725144586 0.05962220832473669 0.8340274686493436 1.1535919862612647 0.02176922017970761 0.1200923806172777 3.6854708875357294e-06 5.43350701505236 0.1712422941713332 LADALQELR ddPTM_PC-9_Lapatinib_30min_R1 2 LADALQELR 9 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ; 106.68 0.011762 16032300.0 40791.0 35357.0 44423.0 39036.0 39941.0 39691.0 37125.0 31656.0 40013.0 36183.0 False True 40209.31285984673 35275.13303882758 40770.71241773894 41906.83766027861 37591.74890702728 37993.50845424003 39047.15084597991 33126.85332590969 35506.31458443045 42437.183339183066 0.9475019239253021 0.8312317232952964 0.9607308781988497 0.9875028068035142 0.885821017068258 0.8952881757154673 0.9201164585757727 0.780609143192664 0.8366793408658391 1.0 15.373041283741701 LADAMAES(ph)PSRDVVGSGTDTALDVAVK ddPTM_PC-9_AZD4547_30min_R2 1 LADAMAESPSRDVVGSGTDTALDVAVK 27 1 Q9H6U6-3;Q9H6U6-8;Q9H6U6-7 Q9H6U6-3 BCAS3 Breast carcinoma-amplified sequence 3 1 LADAMAES(0.628)PS(0.371)RDVVGSGT(0.001)DTALDVAVK 64.962 0.0039448999999999994 0.0 8447.2 5191.2 10720.0 17093.0 14067.0 13343.0 9583.3 11695.0 13152.0 10694.0 True False 11133.233887324977 6869.153880551085 10577.845795676436 13152.472934217465 12114.039864094762 12508.660100698833 10436.195134687941 9887.806474364666 13847.187869659849 10319.606315000266 1.078842888719703 0.665641078823549 1.0250241601078134 1.2745130514426146 1.1738858532312577 1.2121257070162283 1.0112977972345907 0.9581573339665149 1.3418329582526802 1.0 13.333100313660383 -5.516575680663219 24.17839339490526 1.1373247148584005 0.8655146042521783 0.3397143580816747 0.14828228530496063 178.19519534367024 683549.7608682777 0.03861995092587262 0.07013191728743728 3.0438575176404464e-06 5.516575680663219 -0.2718101106062222 LADFGLAR ddPTM_PC-9_AZD4547_30min_R2 1 LADFGLAR 8 0 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YF61;A0A087X209;Q9BVE2;A0A2R8YEB7;A0A2R8Y644;E7EUK8;H0YAZ9;F8VZ51;F8VXD2;F8VTV8;F8VZZ0;F8VYH9;Q96Q40;Q96Q40-5;P11802;Q96Q40-3;Q96Q40-4;Q96Q40-6;Q00534;Q00535;Q00535-2;P11802-2;F8VWX7;Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4;E5RIU6;A0A087WZZ9;P06493;K7ELV5;E7ESI2;A0A024QZP7;P24941-2;G3V5T9;P24941;Q00526;K7EJ83;Q07002;Q07002-3;Q00537-2;Q00537;F5H6Z0;E5RGN0;A0A087WZU2;Q00536;Q00536-3;Q00536-2;O94921;O94921-3;O94921-2;P50750;P50750-2 Q14004;Q9NYV4-2;E5RIU6;G3V5T9;Q07002;Q00537-2;E5RGN0;O94921;P50750 CDK13;CDK14;CDK16;CDK4;CDK15;CDK6;CDK5;CDK12;CDK1;CDK3;CDK2;CDC2;CDK18;CDK17;CDK9 Cyclin-dependent kinase 13;Cyclin-dependent kinase 15;Cyclin-dependent kinase 4;Cyclin-dependent kinase 6;Cyclin-dependent-like kinase 5;Cyclin-dependent kinase 12;Cyclin-dependent kinase 1;Cyclin-dependent kinase 2;Cyclin-dependent kinase 3;Cyclin-dependent kinase 18;Cyclin-dependent kinase 17;Cyclin-dependent kinase 16;Cyclin-dependent kinase 14;Cyclin-dependent kinase 9 0 90.777 0.042485 1565600.0 14335.0 14093.0 24172.0 26854.0 24674.0 24582.0 22479.0 26959.0 21110.0 24786.0 False True 18893.231813477087 18648.28664636431 23851.46348629577 20663.225190164154 21248.44100424212 23044.88365400426 24479.58745240682 22793.10600619042 22225.831503080844 23918.249684271257 0.7899086288868937 0.7796676969480548 0.9972077305464618 0.8639104224985317 0.8883777569315695 0.9634853703011 1.0234690153144734 0.9529587786341768 0.9292415538958374 1.0 14.545824197839043 -3.0875339619597617 0.4056631036976338 0.976648392711489 1.6173639779999363e-15 0.5863088882285008 0.05259950879657822 15.270819607820693 0.6603836760295319 0.03951850800324766 9.639651154787227 0.0008174591098945941 3.0875339619597617 -0.9766483927114873 LADFGLAR ddPTM_PC-9_Lapatinib_30min_R1 2 LADFGLAR 8 0 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YF61;A0A087X209;Q9BVE2;A0A2R8YEB7;A0A2R8Y644;E7EUK8;H0YAZ9;F8VZ51;F8VXD2;F8VTV8;F8VZZ0;F8VYH9;Q96Q40;Q96Q40-5;P11802;Q96Q40-3;Q96Q40-4;Q96Q40-6;Q00534;Q00535;Q00535-2;P11802-2;F8VWX7;Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4;E5RIU6;A0A087WZZ9;P06493;K7ELV5;E7ESI2;A0A024QZP7;P24941-2;G3V5T9;P24941;Q00526;K7EJ83;Q07002;Q07002-3;Q00537-2;Q00537;F5H6Z0;E5RGN0;A0A087WZU2;Q00536;Q00536-3;Q00536-2;O94921;O94921-3;O94921-2;P50750;P50750-2 Q14004;Q9NYV4-2;E5RIU6;G3V5T9;Q07002;Q00537-2;E5RGN0;O94921;P50750 CDK13;CDK14;CDK16;CDK4;CDK15;CDK6;CDK5;CDK12;CDK1;CDK3;CDK2;CDC2;CDK18;CDK17;CDK9 Cyclin-dependent kinase 13;Cyclin-dependent kinase 15;Cyclin-dependent kinase 4;Cyclin-dependent kinase 6;Cyclin-dependent-like kinase 5;Cyclin-dependent kinase 12;Cyclin-dependent kinase 1;Cyclin-dependent kinase 2;Cyclin-dependent kinase 3;Cyclin-dependent kinase 18;Cyclin-dependent kinase 17;Cyclin-dependent kinase 16;Cyclin-dependent kinase 14;Cyclin-dependent kinase 9 0 ; 101.28 0.021347 6633100.0 46546.0 46992.0 52550.0 50233.0 47496.0 54754.0 47693.0 46194.0 44078.0 45939.0 False True 45882.24550450902 46883.19291117987 48229.54184886613 53927.30239237568 44702.37866072876 52412.29905780807 50162.31017635876 48340.34187948797 39113.47147808279 53879.49494013023 0.8515715590038921 0.8701490792234688 0.8951372298953023 1.0008873032736958 0.8296733054086923 0.9727689377201387 0.9310092871527114 0.8971936714180924 0.7259435434861605 1.0 15.717448706764205 -5.229403872431265 3.6461142959758748 0.9070225359624638 0.8576987273644472 0.053953605026863194 0.07834426358958331 0.7724599031948185 21.968172104847984 0.020349284032146923 0.05843859404364939 5.896524774260598e-06 5.229403872431265 -0.04932380859801666 LADFGVLHR ddPTM_PC-9_AZD4547_30min_R2 2 LADFGVLHR 9 0 P26639;P26639-2 P26639 TARS Threonine--tRNA ligase, cytoplasmic 0 ; 134.77 0.00092036 13852600.0 110926.0 110393.0 143816.0 187558.0 169322.0 146862.0 115383.0 161105.0 129061.0 126521.0 False True 146198.1605958677 146075.37839722546 141908.9058722948 144319.40084221386 145814.563010468 137678.69592361784 125651.86347351113 136209.9240746061 135882.9009767466 122091.53829999527 1.1974471173967782 1.1964414604908875 1.162315651422178 1.1820589932088639 1.1943052322936754 1.1276677961524477 1.0291611132359366 1.115637708977997 1.1129592015039085 1.0 16.89760369052251 -6.971667574709257 4.027268314002208 1.0739304297551806 1.184898359179492 0.7352102813512532 0.034284666305171296 0.11964263761625994 4.332797261919531 0.01271024805781775 0.01070530238463868 1.0674128464552548e-07 6.971667574709257 0.11096792942431133 LADFGVLHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LADFGVLHR 9 0 P26639;P26639-2 P26639 TARS Threonine--tRNA ligase, cytoplasmic 0 ; 146.23 0.00037685 10882000.0 98200.0 106623.0 126407.0 128871.0 129467.0 116901.0 119199.0 110667.0 114641.0 96325.0 False True 114823.32046159092 117207.82679314159 129421.022281217 121650.7756754191 104098.87073663596 110770.50576755095 107907.60779397299 107762.108511379 116317.40774553613 113787.95999171936 1.0090990335879728 1.030054733397726 1.1373876664159837 1.069100594511686 0.9148496092575304 0.9734817794045345 0.9483218417996571 0.9470431539437136 1.0222294850351552 1.0 16.79598838727307 -6.2445559198039815 24.844937528303777 0.9643312198405266 1.064597759791672 0.5481264746281354 0.0415978222978058 572.072616726723 841835.8580199376 0.012635269930308958 0.016267628083633124 5.694348989088083e-07 6.2445559198039815 0.10026653995114543 LADFGVLHR ddPTM_PC-9_Lapatinib_30min_R1 2 LADFGVLHR 9 0 P26639;P26639-2 P26639 TARS Threonine--tRNA ligase, cytoplasmic 0 ; 146.79 0.00035098 8239300.0 134339.0 127568.0 135119.0 127481.0 135939.0 135701.0 129355.0 119549.0 132179.0 118980.0 False True 132423.30122524468 127272.6241337543 124010.03739442353 136856.3780041492 127943.33528635692 129897.38456448128 136052.368961124 125103.68297508125 117291.60911342393 139545.5344691156 0.9489612242271556 0.9120508557865923 0.8886707687652275 0.9807291829495156 0.916857252172935 0.930860203149176 0.9749675579280919 0.8965079638773347 0.8405257076813379 1.0 17.09037643257536 -2.278994344817888 14.473066273500667 0.9269730320021182 1.0109725418109305 0.0 0.04606305570308091 0.0 0.0 0.010283895449328562 0.0 0.005260241159891406 2.278994344817888 0.08399950980881232 LADHFGGK ddPTM_PC-9_AZD4547_30min_R2 1 LADHFGGK 8 0 Q9NQ29-3;Q9NQ29;B8ZZ10;A8MYV2;Q9NQ29-2;Q96HJ9-2;A0A0A6YYJ8;Q9Y383-3;Q9Y383-2;Q9Y383 Q9NQ29-3;Q96HJ9-2 LUC7L;LUC7L2 Putative RNA-binding protein Luc7-like 1;Putative RNA-binding protein Luc7-like 2 0 64.207 0.040562 0.0 58826.0 54085.0 66221.0 86096.0 83099.0 73132.0 60033.0 80234.0 69498.0 74525.0 False True 77531.44434318818 71566.91856017978 65342.86627196717 66247.89736994014 71562.13824315119 68559.04447907557 65375.82070066896 67835.67889390113 73171.52239702093 71915.90243364443 1.078084842427238 0.9951473337376716 0.9086010751552192 0.9211856505738204 0.9950808628061137 0.953322452462219 0.9090593107830374 0.9432639596852999 1.0174595593031046 1.0 16.134023202027656 -4.862168478890667 3.357821095377551 0.9522418342341571 1.0843530457624422 0.5040939371407565 0.03653099201539517 0.2152179114825712 4.048273315411571 0.009364937153792267 0.06522965314237504 1.3735090366953278e-05 4.862168478890667 0.1321112115282851 LADILS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LADILSPR 8 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 LADILS(1)PR;LADILS(1)PR 89.82700000000001 0.026817 0.0 14355.9 18287.4 27091.0 28650.0 31192.0 24022.0 26775.0 26877.0 26766.0 20084.1 True False 16786.070328050453 20102.852214783812 27736.952183189616 27044.833384553225 25080.151513645524 22762.244031685867 24238.678165786856 26171.50722853545 27157.402113702916 23725.188344351875 0.7075210567104568 0.8473210801535992 1.1690930238618231 1.1399207033478258 1.0571107444808217 0.9594125745730803 1.0216432347757198 1.1031106201846426 1.1446653960986628 1.0 14.5341319197941 -5.064816427995866 4.04265752480406 1.0730081774341587 0.7294269900112207 0.7787590856992207 0.06512752577960433 0.09902176313828054 3.124532870876001 0.0184390105850765 0.061735765022423325 8.61357762698063e-06 5.064816427995866 -0.343581187422938 LADILS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 LADILSPR 8 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 LADILS(1)PR;LADILS(1)PR 118.03 0.0035207 9012500.0 99985.0 91258.0 87335.0 87825.0 70328.0 71232.0 57763.0 66597.0 63200.0 48302.0 True False 98559.1955649965 91046.69770787502 80154.6534228492 94283.94347561167 66191.44531016797 68185.57340990222 60753.685503470355 69691.33974430141 56081.75047449593 56650.93634163065 1.739762869419142 1.60715256600213 1.414886647936065 1.6642962952463316 1.1684086722062943 1.2036089394659342 1.072421559585499 1.2301886649151086 0.9899527544663644 1.0 15.789812181036783 -6.121773697207084 0.5672188470012995 1.0289933071624244 1.7715510458761223 0.8266758909314497 0.11032339236350167 0.47405278420192454 0.29500242240174174 0.07916784693980139 0.193726850542629 7.554857947401922e-07 6.121773697207084 0.7425577387136979 LADSGDGAGPS(ph)PEEKDFLK ddPTM_PC-9_AZD4547_30min_R2 2 LADSGDGAGPSPEEKDFLK 19 1 Q92917 Q92917 GPKOW G patch domain and KOW motifs-containing protein 1 LADS(0.157)GDGAGPS(0.843)PEEKDFLK;LADS(0.488)GDGAGPS(0.512)PEEKDFLK 61.222 0.0084759 22144000.0 74905.0 66338.0 74096.0 88216.0 81648.0 88249.0 71063.0 71585.0 69858.0 82360.0 True False 98723.23187921161 87780.46118970524 73113.43862653367 67879.16412361363 70312.58454706817 82730.77607933522 77387.46933272782 60523.1831096532 73550.55126206644 79476.60146843303 1.2421672549551968 1.1044818168850663 0.9199366514882155 0.8540773368445337 0.8846954103214305 1.040945064972295 0.9737138717923793 0.7615220327921564 0.9254365423675001 1.0 16.278242561781383 -5.054617702418165 2.4525962490131676 0.9130801945465303 1.2448505080231145 0.6667192749473416 0.07455343086227716 0.20499244132034652 2.164622137014526 0.021081371064168252 0.11096920530060503 8.818247777435416e-06 5.054617702418165 0.33177031347658414 LADSGDGAGPS(ph)PEEKDFLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LADSGDGAGPSPEEKDFLK 19 1 Q92917 Q92917 GPKOW G patch domain and KOW motifs-containing protein 1 LADS(0.022)GDGAGPS(0.978)PEEKDFLK 55.631 0.014387 8596200.0 41884.0 30765.0 26428.0 43079.0 41679.0 49206.0 42914.0 42021.0 38268.0 28838.0 True False 48974.13395329204 33819.14588119819 27058.14374874814 40665.42329400241 33512.299145204925 46625.55073778766 38848.87524954536 40917.99327492976 38827.59710405677 34066.10111851762 1.4376207533380077 0.9927507043890857 0.7942835505187854 1.1937210880847628 0.9837433121158776 1.3686788099282363 1.1403968747227116 1.2011352027804436 1.1397722612568335 1.0 15.056049219297961 -6.706145582435715 24.999875965337036 1.1807240892123358 1.0659509109036047 0.05577451069723083 0.176661207978821 232.56930601434598 105149.75222505124 0.057898105414679525 0.05789806620671266 1.9672267333951438e-07 6.706145582435715 -0.11477317830873113 LADSGDGAGPS(ph)PEEKDFLK ddPTM_PC-9_Lapatinib_30min_R1 1 LADSGDGAGPSPEEKDFLK 19 1 Q92917 Q92917 GPKOW G patch domain and KOW motifs-containing protein 1 LADS(0.006)GDGAGPS(0.994)PEEKDFLK 57.227 0.0127 11590000.0 67865.0 61683.0 67305.0 56842.0 65319.0 61546.0 51557.0 55713.0 58814.0 57585.0 True False 66897.2326550831 61540.176803292255 61771.44270481321 61022.35029935334 61477.064842094966 58913.82105073338 54226.36918966154 58301.62937030594 52189.74798112349 67538.49052281062 0.9905052976049126 0.911186737028236 0.9146109459457104 0.903519605294458 0.9102522778671156 0.8722999373347806 0.8028957823886661 0.8632355997150247 0.7727408116042628 1.0 16.04342231519346 LAEAEETAR ddPTM_PC-9_Lapatinib_30min_R1 1 LAEAEETAR 9 0 Q8N163-2;Q8N163;G3V119;H0YB24 Q8N163-2 CCAR2 Cell cycle and apoptosis regulator protein 2 0 93.14299999999999 0.019118 0.0 14474.0 14822.0 21036.0 12645.0 19621.0 17114.0 16633.0 14001.0 18077.0 14512.0 False True 14267.598105793484 14787.680569660974 19306.501281308247 13574.955482483427 18466.931356370216 16382.074114682537 17494.175354105955 14651.537573163423 16040.977900750993 17020.379863975486 0.8382655510522179 0.8688220056098668 1.1343167094743551 0.7975706530037865 1.0849893776728468 0.9624975614883922 1.0278369515790469 0.8608231831637413 0.9424571031286177 1.0 14.054975615266516 -5.026561477875232 24.643686687481612 0.9722777082542233 0.8459045255968692 0.21937028328834063 0.09316858554726895 747.1530339664823 693210.3044206189 0.022312015094086257 0.05946947047154624 9.406726608339629e-06 5.026561477875232 -0.1263731826573541 LAEDEAFQRR ddPTM_PC-9_Lapatinib_30min_R1 1 LAEDEAFQRR 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 87.258 0.025386000000000002 0.0 29602.0 17479.0 29187.0 19515.0 20436.0 19450.0 14816.0 15719.0 24348.0 15306.0 False True 29179.87005165804 17438.528449406556 26787.35752507812 20950.198200131603 19233.994658721866 18618.16884016449 15583.099984755227 16449.362125030777 21605.67184419347 17951.621706036993 1.625472646955627 0.9714179997198867 1.4921970818976058 1.1670365242314689 1.0714349362795241 1.0371301905221935 0.8680608493167361 0.916316218912912 1.2035498629590469 1.0 14.131826559061622 -6.178521107829514 2.0676322530648337 0.9953773817931992 1.3264025045665861 0.42286115956286174 0.17841714023548855 0.32340234701714776 2.716730805120353 0.0569081739460257 0.07835341081586197 6.629471259511733e-07 6.178521107829514 0.3310251227733869 LAEDEGDS(ph)EPEAVGQSR ddPTM_PC-9_AZD4547_30min_R2 2 LAEDEGDSEPEAVGQSR 17 0 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 LAEDEGDS(1)EPEAVGQSR;LAEDEGDS(1)EPEAVGQSR 235.02 2.7906e-37 332670000.0 101932.0 101462.0 121113.0 132686.0 121569.0 116289.0 110469.0 151113.0 107351.0 107493.0 True False 134344.25568268925 134257.60730244932 119506.96248617167 102097.29267826486 104691.24278368798 109017.43044668886 120300.52699319065 127761.95808128835 113025.35469858986 103729.70278832274 1.2951377674034261 1.294302438872535 1.1520997291397332 0.984262847900094 1.0092696688558669 1.0509760224528608 1.1597500403397796 1.2316815207887688 1.0896141766571568 1.0 16.662469540521677 -5.371635512902767 3.609310156627708 1.0836845760306464 1.2963438435444583 0.5891435882523429 0.07208142769648489 0.1850680093116764 4.34550880188012 0.021894691947039045 0.05108654122103191 4.2497608083187585e-06 5.371635512902767 0.21265926751381192 LAEDEGDS(ph)EPEAVGQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LAEDEGDSEPEAVGQSR 17 0 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 LAEDEGDS(1)EPEAVGQSR 200.71 1.2083e-12 110580000.0 64531.0 73938.0 60626.0 73940.0 79177.0 50860.0 76272.0 55028.0 57370.0 48318.0 True False 75454.82375465307 81278.07600078105 62071.55376538534 69797.38151671417 63662.83522685023 48192.812066087055 69046.96399853953 53583.57330698548 58208.92771662317 57077.67091492244 1.3219674619716497 1.4239907602735 1.0874927580332872 1.2228491527054632 1.1153719870900716 0.8443373966313591 1.2097018482316493 0.9387834585411673 1.0198196034205202 1.0 15.800638845616685 -5.527833555889645 0.7887712791356791 1.0082327014023886 1.433788412244922 0.5769913116757599 0.110018923542954 0.7901510841828794 0.7402184620127151 0.047653862593551435 0.24772152868627012 2.965967884043425e-06 5.527833555889645 0.4255557108425334 LAEDEGDS(ph)EPEAVGQSR ddPTM_PC-9_Lapatinib_30min_R1 2 LAEDEGDSEPEAVGQSR 17 0 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 LAEDEGDS(1)EPEAVGQSR;LAEDEGDS(1)EPEAVGQSR 157.7 2.8116e-05 331840000.0 100470.0 123238.0 106328.0 88191.0 93809.0 99981.0 105686.0 96146.0 97352.0 84876.0 True False 99037.27937605827 122952.64998272037 97586.12227794934 94676.86033655163 88291.33905559019 95705.04569709451 111157.90395443054 100613.29415822927 86387.19259799254 99546.70350983902 0.9948825614930544 1.2351252793676684 0.9803049105318098 0.9510798147845643 0.8869338304795159 0.9614084879027178 1.1166407327937675 1.0107144748222108 0.8678056585716492 1.0 16.603085921424395 -5.394935049387259 9.946210567435958 0.972746830993894 1.1147888376435415 0.31702684226561706 0.08409923504504462 0.4232598870419114 31.854914896960196 0.022228445815177876 0.04632306003234912 4.027772668986397e-06 5.394935049387259 0.1420420066496475 LAELSDYRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LAELSDYRR 9 1 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 0 ; 107.57 0.0027438000000000002 1538300.0 16891.5 17205.4 22160.2 25000.2 24219.0 23775.0 26808.9 25963.0 25379.0 17809.1 False True 19750.897327667673 18913.438405472694 22688.583211026496 23599.519845741976 19473.460807546195 22528.197146504528 24269.366912372127 25281.498760072394 25750.1198626491 21037.748853241963 0.9388313105859716 0.8990238707293101 1.0784701048244587 1.1217702050904195 0.9256437532072398 1.070846377322015 1.1536104495625332 1.201720722898375 1.2239959723010454 1.0 14.36069271668826 -7.092445021593921 3.3598565769876303 1.1615371587987653 0.9990603150200714 0.4057965981555465 0.08522785296501097 0.2512344524244321 5.367995120283224 0.03554082093881551 0.027325536855856026 8.082672431735621e-08 7.092445021593921 -0.16247684377869387 LAEQAER ddPTM_PC-9_Lapatinib_30min_R1 1 LAEQAER 7 0 P31947-2;P31947;P63104;E7EX29;E7ESK7;E9PD24;E7EVZ2;E5RIR4;E5RGE1;I3L3T1;B4DJF2;I3L0W5;P62258;P27348;E9PG15;P31946-2;P31946;Q4VY20;Q4VY19;A0A0J9YWE8;P61981;Q04917;F8WEB6;A2IDB1 P31947-2;P63104;I3L3T1;P62258;P27348;P31946-2;P61981;Q04917 SFN;YWHAZ;YWHAE;YWHAQ;YWHAB;YWHAG;YWHAH 14-3-3 protein sigma;14-3-3 protein zeta/delta;14-3-3 protein epsilon;14-3-3 protein theta;14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed;14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed;14-3-3 protein eta 0 110.12 0.043826 85162000.0 43677.0 59320.0 54359.0 50968.0 62162.0 51934.0 41889.0 50949.0 68775.0 52902.0 False True 43054.157970619155 59182.64818460991 49889.8128518081 54716.35674426377 58505.75337519417 49712.90388406697 44057.80745554886 53316.27653846892 61028.8352671434 62046.0402125159 0.6939066187488028 0.9538505274776844 0.8040773058349717 0.881867022566678 0.9429409705245365 0.8012260526827125 0.7100825017139697 0.8593018403084808 0.9836056428115566 1.0 15.921051519831638 -8.24359597311127 4.275690212604829 0.9968279530142938 0.8334446285884819 0.39004942956757593 0.08101009341992743 0.21386361155817735 9.39801592102004 0.0674003311109491 0.020903164131443847 5.706949464967505e-09 8.24359597311127 -0.16338332442581194 LAERLS(ph)PFLAESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LAERLSPFLAESK 13 1 H9KVB4;O15417;O15417-2 H9KVB4 TNRC18 Trinucleotide repeat-containing gene 18 protein 1 LAERLS(1)PFLAESK 91.40100000000001 0.0024216999999999997 3959200.0 22319.0 15647.0 18734.0 30001.0 34481.0 23553.0 22900.0 22906.0 27127.0 20879.0 True False 26097.165879656317 17200.330752579506 19180.68960909064 28320.141234554332 27724.695573929577 22317.839217313183 20730.746218357395 22304.74177091314 27523.681055758014 24664.19742192694 1.0580991318393942 0.6973805171251218 0.7776733733098748 1.1482287767197805 1.124086671041718 0.9048678469250413 0.8405197973288752 0.9043368162097097 1.1159366179614236 1.0 14.590130722051347 -5.736857532591355 24.999699985313352 0.9953225933516142 0.829683914164254 0.2408809712510963 0.1293589484586812 344.5295761482425 350383.2220190072 0.03690272858382811 0.06388034569853217 1.8329155994991523e-06 5.736857532591355 -0.1656386791873602 LAGAPS(ph)EDPQFPK ddPTM_PC-9_AZD4547_30min_R2 1 LAGAPSEDPQFPK 13 0 O00391-2;O00391 O00391-2 QSOX1 Sulfhydryl oxidase 1 1 LAGAPS(1)EDPQFPK 69.45100000000001 0.030485 9431400.0 26101.0 22853.0 27884.0 35197.0 33580.0 29226.0 28666.0 33917.0 28242.0 35870.0 True False 34400.57506547368 30239.785335227665 27514.239940918043 27082.87543822923 28917.996632992257 27398.49359986691 31217.218466599632 28675.906985124107 29734.81446281428 34614.202217978265 0.9938283381151095 0.8736236399382167 0.794882972245058 0.7824209053751544 0.8354373286111024 0.7915390748377962 0.9018615616218283 0.828443388772662 0.8590350941952468 1.0 15.079076477106652 -10.293966301121197 6.218737974185097 1.0000000034910272 0.8468066406630266 0.35495883841109077 0.05989797553228235 3.0236443427918657e-09 5.720093583824757e-10 0.059679513975398495 0.014474407792516903 5.081988744865428e-11 10.293966301121197 -0.15319336282800067 LAGASPAT(ph)VAAAAAGSGPKDPMAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LAGASPATVAAAAAGSGPKDPMAR 24 1 Q13045-2;J3KS54 Q13045-2 FLII Protein flightless-1 homolog 1 LAGAS(0.008)PAT(0.829)VAAAAAGS(0.163)GPKDPMAR 55.302 0.005107199999999999 4851800.0 15490.0 11307.0 16018.0 16828.0 16340.0 14964.0 16789.0 14226.0 13991.0 12408.0 True False 18112.15105855443 12429.484234640271 16399.929868603274 15885.18171711211 13138.294297671462 14179.26149738354 15198.624378166034 13852.582573692946 14195.591906628462 14657.472178326037 1.2356940431609222 0.8479964405472121 1.1188784579686124 1.0837599774264952 0.8963547150441821 0.9673742733314121 1.0369198858613695 0.9450867383652087 0.9684884087734749 1.0 13.839348697874888 -4.738911377463435 24.99855439687227 0.9888422208531966 1.2356950364915698 0.4866342915753613 0.07715954075891193 1709.0945105713017 1896426.9273560522 0.019107884358227748 1.025063798757308 1.8242679261526718e-05 4.738911377463435 0.24685281563837314 LAGEDKDSEPAADGPAASEDPSATESDLPNPHVGEVSVLS(ph)SGSPR ddPTM_PC-9_Lapatinib_30min_R1 1 LAGEDKDSEPAADGPAASEDPSATESDLPNPHVGEVSVLSSGSPR 45 1 O14686;O14686-3;F8VWW4 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 LAGEDKDSEPAADGPAASEDPS(0.002)AT(0.002)ES(0.002)DLPNPHVGEVS(0.193)VLS(0.426)S(0.338)GS(0.037)PR 70.156 1.7150000000000002e-09 7959800.0 6890.8 5613.4 8171.7 7385.2 8988.8 10335.0 8242.7 7371.1 12453.0 7127.6 True False 6792.535928382049 5600.4025171862695 7499.854369674204 7928.33224430499 8460.096456660747 9892.996142061695 8669.46667415915 7713.588215523525 11050.412004096483 8359.596163069986 0.81254354826245 0.6699369691955995 0.8971551045499249 0.9484109147915325 1.012022146959053 1.1834299108569117 1.0370676411927735 0.9227225891125798 1.3218834724234239 1.0 13.029217534670574 -5.783519476799972 1.3215728598604701 1.082965159130181 0.7350967561344661 0.59178284152359 0.11034444655107525 0.3141937201468503 1.0964525646594045 0.03693749886716147 0.08893797524324283 1.6461921379116653e-06 5.783519476799972 -0.34786840299571486 LAGEDKDSEPAADGPAASEDPSATESDLPNPHVGEVSVLSS(ph)GSPR ddPTM_PC-9_Lapatinib_30min_R1 1 LAGEDKDSEPAADGPAASEDPSATESDLPNPHVGEVSVLSSGSPR 45 1 O14686;O14686-3;F8VWW4 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 LAGEDKDSEPAADGPAASEDPS(0.001)AT(0.001)ES(0.001)DLPNPHVGEVS(0.06)VLS(0.152)S(0.393)GS(0.393)PR 101.36 5.0917000000000004e-24 6263200.0 21322.0 17741.0 23494.0 18704.0 20018.0 20429.0 17379.0 18599.0 26506.0 15336.0 True False 21017.944370024077 17699.92180450378 21562.414009462624 20079.554554714905 18840.58059690224 19555.29929232495 18278.799583899923 19463.17743898767 23520.615159446024 17986.807166064507 1.16852002559289 0.9840502342126629 1.1987905252102868 1.1163490201084025 1.0474666472462404 1.0872023651434757 1.0162336992407588 1.0820807305761644 1.3076592717256728 1.0 14.134651496406144 LAGESESNLR ddPTM_PC-9_Lapatinib_30min_R1 2 LAGESESNLR 10 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 ; 131.62 0.00080096 9296700.0 31688.0 29262.0 31965.0 26282.0 32975.0 33267.0 32020.0 31007.0 35275.0 32855.0 False True 31236.123309132483 29194.245636851927 29336.961088468226 28214.86595418186 31035.475331344354 31844.247959164622 33677.83892493671 32447.69841661868 31301.958037782366 38533.94297346434 0.8106132126328893 0.757624145988797 0.7613277755839977 0.7322081203475981 0.8054061675628766 0.8263947445267553 0.8739785323326063 0.8420549757641766 0.81232169932202 1.0 15.23384219641159 -11.794353223063586 0.16078237524157774 1.2973799505737122 0.7265446737079627 0.7941197461433647 0.03246496603996387 21.187498462886808 0.44810984600586407 2.4624159048029983 0.17313262090091794 1.6056348170043775e-12 11.794353223063586 -0.5708352768657495 LAGGQTSQPTTPLT(ph)SPQR ddPTM_PC-9_AZD4547_30min_R2 1 LAGGQTSQPTTPLTSPQR 18 0 O95155-2;O95155;O95155-4;B1AQ61 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 LAGGQTSQPT(0.001)T(0.006)PLT(0.908)S(0.085)PQR 109.67 0.00059511 11239000.0 16623.0 14927.0 14405.0 24319.0 28521.0 32026.0 22845.0 36446.0 29081.0 29237.0 True False 21908.768220120663 19751.860836605414 14213.98028794021 18712.630274804567 24561.35145829575 30023.409157234575 24878.16074337085 30814.108145762682 30618.16228996182 28213.421529050203 0.7765370888306511 0.700087396924465 0.5038020742469912 0.6632527804377409 0.8705555769974915 1.0641534252171685 0.8817846044569542 1.0921790579010298 1.085233928768106 1.0 14.784094016180674 -6.441424082135649 2.8172120628326662 1.0210293617324617 0.651356639588188 0.802334725754752 0.08487996700005634 0.12271424801235543 1.903930070290029 0.030282588237453004 0.033972492397147426 3.618894461359613e-07 6.441424082135649 -0.3696727221442737 LAGGQTSQPTTPLTS(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 1 LAGGQTSQPTTPLTSPQR 18 0 O95155-2;O95155;O95155-4;B1AQ61 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 LAGGQTS(0.001)QPT(0.008)T(0.127)PLT(0.023)S(0.842)PQR 110.26 0.00022955 10293000.0 20274.0 20108.0 16610.0 21022.0 26023.0 33602.0 27686.0 49074.0 34612.0 23605.0 True False 26720.710274603032 26607.517766628367 16389.740547218797 16175.702686662353 22410.155639677112 31500.861628095787 30150.000365111213 41490.740908334454 36441.51965820153 22778.59613480281 1.173062207893364 1.1680929592485048 0.7195237340451086 0.710127287517422 0.9838251447567145 1.3829149716547482 1.3236109980915738 1.821479280935222 1.5998141168376703 1.0 14.47539121475312 -6.826387399559942 2.825663488693167 1.493551842745591 0.9297625740790801 0.4794593459945151 0.24496001085333313 0.22192438152852031 3.604502150288057 0.0965190159187058 0.08628385040320159 1.4914634001674517e-07 6.826387399559942 -0.5637892686665108 LAGGQTSQPTTPLTS(ph)PQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LAGGQTSQPTTPLTSPQR 18 0 O95155-2;O95155;O95155-4;B1AQ61 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 LAGGQTSQPTT(0.001)PLT(0.211)S(0.788)PQR 185.63 2.1506999999999996e-42 0.0 13700.0 15538.0 14702.0 12245.0 19312.0 21967.0 28570.0 14342.0 21452.0 23778.0 True False 16019.139412665956 17080.5099529354 15052.551437645496 11558.952348825633 15527.952232351974 20815.011849306615 25863.64277111226 13965.537696605099 21765.694916803222 28088.76317345558 0.5703041929523031 0.608090496810369 0.5358922834975677 0.41151517699252294 0.552817229312047 0.741044086589658 0.9207825425205585 0.4971930451463523 0.7748897586694818 1.0 14.777705479527938 -6.764275947463042 4.914330649515835 0.7658452729460892 0.5311162165567141 0.4744080126167247 0.13154716488470722 0.18507112162657785 11.992492972670059 0.04584286127054977 0.04279908459167506 1.7207748600878323e-07 6.764275947463042 -0.23472905638937502 LAGGQTSQPTTPLTS(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 2 LAGGQTSQPTTPLTSPQR 18 0 O95155-2;O95155;O95155-4;B1AQ61 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 LAGGQTSQPT(0.001)TPLT(0.08)S(0.918)PQR;LAGGQTSQPTT(0.002)PLT(0.057)S(0.941)PQR 236.68 2.3146999999999996e-43 19372100.0 19759.6 27296.0 30241.0 22738.5 52832.0 63926.0 69651.0 53730.0 65049.0 62145.0 True False 19477.824480533163 27232.797789061253 27754.701713635797 24410.765143412358 49724.52563170843 61192.03399878437 73257.18797503968 56226.49195100854 57722.496623662766 72886.68044699251 0.2672343473606071 0.3736320219558709 0.38079250616744237 0.3349139375494718 0.6822169061173122 0.8395502940113567 1.0050833365681486 0.7714234151725398 0.7919484914070406 1.0 16.153367575325717 -6.437953879246147 2.3283285592166645 0.8768255532968412 0.3378407818499671 0.9147390724756835 0.07806707846083294 0.08453946334284172 0.9043072567185683 0.02788614018492978 0.03164926269415521 3.647926847429112e-07 6.437953879246147 -0.5389847714468741 down LAGS(ph)PIR ddPTM_PC-9_AZD4547_30min_R2 4 LAGSPIR 7 0 Q8WXG6-4;Q8WXG6-7;Q8WXG6-2;Q8WXG6;A0A0A0MRB5;Q8WXG6-6;Q8WXG6-8;Q8WXG6-5;Q8WXG6-3;F8W8U2 Q8WXG6-4 MADD MAP kinase-activating death domain protein 1 LAGS(1)PIR;LAGS(1)PIR;LAGS(1)PIR;LAGS(1)PIR 93.14299999999999 0.014112999999999999 60304100.0 120853.0 123286.0 160069.0 186697.0 168951.0 169275.0 144265.0 181231.0 144831.0 156561.0 True False 159281.74010144066 163135.78851086856 157946.38047277337 143656.89108989638 145495.06995654164 158690.20749050364 157104.30552166334 153225.9132240775 152486.47098165346 151079.84704345962 1.054288465460398 1.0797984754640433 1.045449698048334 0.9508673320841531 0.9630342683275853 1.0503731013498765 1.0398759900549193 1.0142048474539462 1.009310467052493 1.0 17.204951702712272 -5.534418461578903 24.99181667147301 1.0056462723770687 1.0659386350877234 0.4481086593289304 0.0290431670799559 207.56213146792697 449520.57217602374 0.00877087667736846 0.015208336607512526 2.9213361871167342e-06 5.534418461578903 0.060292362710654634 LAGS(ph)PIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LAGSPIR 7 0 Q8WXG6-4;Q8WXG6-7;Q8WXG6-2;Q8WXG6;A0A0A0MRB5;Q8WXG6-6;Q8WXG6-8;Q8WXG6-5;Q8WXG6-3;F8W8U2 Q8WXG6-4 MADD MAP kinase-activating death domain protein 1 LAGS(1)PIR;LAGS(1)PIR;LAGS(1)PIR;LAGS(1)PIR 95.741 0.013028999999999999 31488800.0 122785.0 185750.0 178159.0 152136.0 163414.0 116020.0 133174.0 111332.0 101719.0 89871.0 True False 143570.0753857076 204190.03242101613 182406.98623176964 143612.31315156686 131394.19977721415 109935.7069584628 120558.79462373504 108409.65296600485 103206.4479415584 106163.90088155563 1.3523436327559695 1.9233471144662042 1.7181639400692 1.3527414870690506 1.2376542184881405 1.0355281413511292 1.1355912284933787 1.0211536319389276 0.9721425746846211 1.0 16.69593376155259 -6.140922675492069 1.61539490953206 1.0428367528185856 1.692891071054666 0.7760992110819513 0.14497712668720614 0.16613322043342524 0.8636556408819357 0.05013943235572796 0.0749175889855645 7.228985015187768e-07 6.140922675492069 0.6500543182360805 LAGS(ph)PIR ddPTM_PC-9_Lapatinib_30min_R1 4 LAGSPIR 7 0 Q8WXG6-4;Q8WXG6-7;Q8WXG6-2;Q8WXG6;A0A0A0MRB5;Q8WXG6-6;Q8WXG6-8;Q8WXG6-5;Q8WXG6-3;F8W8U2 Q8WXG6-4 MADD MAP kinase-activating death domain protein 1 LAGS(1)PIR;LAGS(1)PIR;LAGS(1)PIR;LAGS(1)PIR 80.438 0.025405 53862000.0 107832.0 165338.0 165894.0 143830.0 164569.0 145786.0 132331.0 146232.0 137622.0 113079.0 True False 106294.29590603306 164955.17001933634 152254.83568935905 154407.73800281467 154889.37497510275 139551.07262376472 139182.4516794441 153026.47256616206 122121.56113609314 132624.55448170338 0.8014676944358536 1.2437754883624752 1.1480139276197443 1.164246987341371 1.1678785695485294 1.052226513929718 1.0494470818271093 1.1538321328519394 0.9208065701961757 1.0 17.016988379219704 -8.263507359333811 24.98260556398394 0.9604032761303408 1.1056084592669597 0.18302450896814892 0.1149656741569986 292.1922339825037 3529736.2852989007 0.09075027915948931 0.027802981788015168 5.451206582727119e-09 8.263507359333811 0.1452051831366189 LAGS(ph)PPGSGQWKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LAGSPPGSGQWKPK 14 1 H3BLU1;Q4KMQ1 H3BLU1 TPRN Taperin 1 LAGS(0.929)PPGS(0.071)GQWKPK 57.567 0.031444 33254000.0 118160.0 117480.0 123590.0 136040.0 152350.0 135780.0 125320.0 157190.0 119300.0 117690.0 True False 138162.15423362146 129142.63800172784 126536.85431768499 128418.11984763101 122498.11115362585 128659.457772971 113448.78236177047 153063.9290565722 121044.53680657406 139026.26536647245 0.9937845476135521 0.9289082006289141 0.9101650971068996 0.9236968245469414 0.8811148802042659 0.925432740596357 0.8160240948911353 1.1009713067749936 0.8706594864466894 1.0 17.08499794252441 -7.7542443843321545 24.99997431494312 0.9893615503795224 0.9117960529893134 0.23002005206206066 0.06642207461981114 234.13502783924 813541.4963903265 0.030088889540134504 0.01690618449413244 1.7609848337033746e-08 7.7542443843321545 -0.07756549739020902 LAGTQPLEVLEAVQR ddPTM_PC-9_Lapatinib_30min_R1 2 LAGTQPLEVLEAVQR 15 0 P22314;P22314-2;Q5JRR6 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 ; 155.14 0.00086447 8590900.0 17981.4 16394.1 19105.5 16308.8 14764.400000000001 17839.1 16199.9 12845.7 17658.9 11504.9 False True 17724.981938615092 16356.140468700494 17534.719539362733 17508.203556561934 13895.98701992724 17076.163277973184 17038.651555280525 13442.558117533412 15669.968725539191 13493.506635684365 1.3135934503296824 1.2121489921267556 1.2994931571746624 1.297528065110997 1.0298277086238274 1.2655096809908757 1.2627296977214817 0.9962242195800892 1.1612969962973927 1.0 13.719977698072732 -7.553307610533773 0.2356625886800509 0.9587532570553658 1.3484799074421208 0.4541895105948197 0.09049989280053142 2.3069256095620463 0.494968699830481 0.25869278787070227 0.34907220900877245 2.796999504704492e-08 7.553307610533773 0.3897266503867549 LAHCEELR ddPTM_PC-9_AZD4547_30min_R2 1 LAHCEELR 8 0 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 0 127.46 0.0030328000000000004 1828400.0 2626.0 7064.0 8171.8 10668.0 8754.7 8208.9 5249.4 11161.0 5545.6 5808.3 False True 3461.013375806823 9347.299855951003 8063.436592640733 8208.657418956993 7539.261022122015 7695.5961853126455 5716.586430564721 9436.323904265419 5838.729094433212 5604.953184908928 0.6174919328720601 1.6676856251213956 1.4386269299003522 1.464536303542805 1.345106867693582 1.3729991904361798 1.0199168917157704 1.6835687280443796 1.0417088068021183 1.0 12.452486607704959 LAHCEELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LAHCEELR 8 0 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 0 93.162 0.0084236 0.0 3465.9 1627.9 1831.4 3955.4 6572.5 5114.9 6192.1 6184.8 4661.5 4728.2 False True 4052.6084153546676 1789.5071535837017 1875.067521623178 3733.79176157982 5284.665806086023 4846.665639733161 5605.539461078203 6022.455553337275 4729.66561880842 5585.3852315893955 0.7255736618549128 0.32039099889883044 0.3357096142658727 0.6684931489528289 0.9461595909620366 0.8677406192721961 1.0036083866471412 1.0782524935390188 0.8467930899481629 1.0 12.4474410734346 -6.08982935738991 2.8778518751504314 0.9611815256384854 0.44812501722605314 0.7711842762141056 0.12206275041596502 0.12057528041593366 1.9412814741787707 0.03786717344273845 0.05295795854878211 8.13149955576348e-07 6.08982935738991 -0.5130565084124322 LAHCEELR ddPTM_PC-9_Lapatinib_30min_R1 1 LAHCEELR 8 0 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 0 110.12 0.0031617 2339200.0 5409.5 5636.4 8015.7 5087.7 6360.9 7763.5 7062.9 7290.8 6367.9 5425.0 False True 5332.359538019196 5623.349262099383 7356.680087496794 5461.866430069669 5986.764368010565 7431.473202602416 7428.582402964882 7629.5571843739635 5650.680045040233 6362.704021641882 0.8380649987618303 0.8837986558815744 1.1562191267225437 0.8584190638904254 0.9409151121358766 1.1679740527494693 1.1675197176699652 1.1991060967826024 0.8880941225334709 1.0 12.635424296957197 -6.745935169778919 24.3542073265599 1.1021692246321053 0.9405936934768508 0.27604676231752 0.11884836675619016 226.36790947638124 355580.52271352883 0.039538671139284665 0.03938868829076566 1.79500155946236e-07 6.745935169778919 -0.16157553115525447 LAHEVGWK ddPTM_PC-9_Lapatinib_30min_R1 1 LAHEVGWK 8 0 P40429;M0QYS1;Q8J015 P40429 RPL13A;RPL13a 60S ribosomal protein L13a 0 77.923 0.019183000000000002 8821100.0 179220.0 171940.0 160550.0 147070.0 170220.0 163300.0 157580.0 136870.0 169290.0 147400.0 False True 176664.28993507742 171541.88349396197 147350.19874092191 157886.01841113812 160207.99426539626 156316.03967089276 165738.72135513846 143229.47986850084 150222.77749726942 172877.8936018455 1.0219021429191655 0.9922719436242062 0.8523368469555954 0.913280553815428 0.926711859610985 0.9041991223638095 0.9587039609404934 0.8285008388543429 0.8689530764601227 1.0 17.399393873607785 -5.111573847064555 5.522263079956125 0.9034275864035576 1.0149652740089088 0.4212386226856242 0.047481833523632645 0.18719661616000569 7.713063447713934 0.011882584023953044 0.033399579411265715 7.734391526568617e-06 5.111573847064555 0.11153768760535121 LAHYIDR ddPTM_PC-9_Lapatinib_30min_R1 1 LAHYIDR 7 0 Q03252 Q03252 LMNB2 Lamin-B2 0 98.41799999999999 0.004802300000000001 0.0 24715.0 23665.0 28641.0 28023.0 27929.0 26964.0 25439.0 20181.0 23955.0 18868.0 False True 24362.559567824082 23610.205146473254 26286.247537457188 30083.904901987607 26286.27113052665 25810.81257615402 26756.106946017047 21118.682934362627 21256.935642666926 22129.308659970335 1.100918241151088 1.0669201423893422 1.1878476612785618 1.359459771845757 1.1878487274243608 1.1663632593657638 1.2090801098732975 0.9543308947813708 0.9605783881137939 1.0 14.43367076026759 -7.763134108700477 24.999992251103606 0.968090922757643 1.1847597544733406 0.6352199852057363 0.07324523228691768 31.21988897738723 460515.5371127996 0.041858509649447206 0.021770854855012612 1.725305041229323e-08 7.763134108700477 0.21666883171569762 LAHYNK ddPTM_PC-9_Lapatinib_30min_R1 1 LAHYNK 6 0 Q16778;P33778;P23527;P06899;Q6DRA6;Q6DN03;Q8N257;U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814 Q16778;Q8N257;U3KQK0 HIST2H2BE;HIST1H2BB;HIST1H2BO;HIST1H2BJ;HIST2H2BD;HIST2H2BC;HIST3H2BB;HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK Histone H2B type 2-E;Histone H2B type 1-B;Histone H2B type 1-O;Histone H2B type 1-J;Putative histone H2B type 2-D;Putative histone H2B type 2-C;Histone H2B type 3-B;Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K 0 96.839 0.019816999999999998 0.0 41293.0 93808.0 30554.0 76721.0 77927.0 47245.0 178810.0 274330.0 71707.0 108950.0 False True 40704.154247791244 93590.7933395462 28041.968061850745 82363.31827375334 73343.48707037668 45224.441483474104 188067.90687595052 287076.3732909018 63630.602551814496 127781.86233325044 0.3185440680277166 0.7324262742036489 0.2194518654667774 0.6445618867171681 0.5739741597997652 0.35391909820135825 1.4717887456161522 2.2466128451173852 0.4979627107473845 1.0 16.963323545628626 -7.2640388654219334 24.910218800996603 1.4079755267223342 0.48632027053301147 0.45716402290887603 0.4372804122674168 178.2825818708039 1708421.8983117107 0.16919602855352567 0.11998967674256858 5.4445392696783975e-08 7.2640388654219334 -0.9216552561893228 LAIEAGFR ddPTM_PC-9_AZD4547_30min_R2 1 LAIEAGFR 8 0 A0A0A0MSS8;P42330;S4R3Z2;S4R3D5;A6NHU4;P17516;Q04828 A0A0A0MSS8;Q04828 AKR1C3;AKR1C1;AKR1C4 Aldo-keto reductase family 1 member C3;Aldo-keto reductase family 1 member C4;Aldo-keto reductase family 1 member C1 0 96.19 0.028547000000000003 7141500.0 19895.0 21215.0 28931.0 36681.0 26850.0 24374.0 22126.0 30145.0 20812.0 25679.0 False True 26221.196158292743 28072.333868063513 28547.35603682041 28224.76216580068 23122.34096473621 22849.889926885495 24095.171136258406 25486.782913187093 21912.07983145991 24779.986026079296 1.0581602479798282 1.1328631839630272 1.1520327738190088 1.1390144504559438 0.9331054884535236 0.92211068653701 0.9723641938659624 1.0285228928847636 0.8842652214734461 1.0 14.59688775346413 -6.259614183883765 24.99980703959868 0.9572051582039613 1.1236505725920658 0.765640432647295 0.04437963631271051 78.03303531498265 1068822.838088642 0.013429543729048476 0.016464250144341237 5.500292888380996e-07 6.259614183883765 0.16644541438810445 LAIEAGFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LAIEAGFR 8 0 A0A0A0MSS8;P42330;S4R3Z2;S4R3D5;A6NHU4;P17516;Q04828 A0A0A0MSS8;Q04828 AKR1C3;AKR1C1;AKR1C4 Aldo-keto reductase family 1 member C3;Aldo-keto reductase family 1 member C4;Aldo-keto reductase family 1 member C1 0 99.375 0.024045 4405000.0 16915.0 17081.0 22083.0 22953.0 19022.0 15645.0 16521.0 15460.0 12491.0 13150.0 False True 19778.375413521513 18776.688795603655 22609.542470243858 21667.017824630035 15294.775650569552 14824.548658551545 14956.011278318016 15054.191381224018 12673.657244349659 15533.99090465728 1.2732320711988905 1.208748538018918 1.4554883293684202 1.3948133456247873 0.9846005282508562 0.9543296857542877 0.9627925862782643 0.9691129262030524 0.8158661429723087 1.0 13.923140905905825 -6.30746452243319 5.986939048165912 0.9450364265087763 1.3329359886649776 0.8566885998794554 0.07724140587292741 0.07819574189035206 7.171943369068247 0.025437655907168732 0.02925068769642817 4.926465860628346e-07 6.30746452243319 0.38789956215620136 LAILGIHNEVSK ddPTM_PC-9_AZD4547_30min_R2 1 LAILGIHNEVSK 12 0 P12814-4;P12814-3;P12814;P12814-2;H9KV75;H7C5W8 P12814-4 ACTN1 Alpha-actinin-1 0 124.6 0.00071963 0.0 21001.0 20913.0 29415.0 37789.0 31438.0 28084.0 22855.0 29441.0 26117.0 27204.0 False True 27678.881152063645 27672.718273995368 29024.93788058043 29077.32988423004 27073.376359380898 26327.90304039767 24889.05072399829 24891.569936876473 27497.49130108775 26251.596240253166 1.0543694523848397 1.0541346903531568 1.1056446859438867 1.1076404504364579 1.0313040057300458 1.0029067489628496 0.9480966603407681 0.9481926245196747 1.0474597829949928 1.0 14.680117528723708 -6.61091112614124 2.6481910430144278 0.9822507043577307 1.0799139597269356 0.6420690907555597 0.03180861938215554 0.17354146704247797 2.4697045999038925 0.011832781900119696 0.011981478094380429 2.4495644685053036e-07 6.61091112614124 0.09766325536920495 LAILGIHNEVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LAILGIHNEVSK 12 0 P12814-4;P12814-3;P12814;P12814-2;H9KV75;H7C5W8 P12814-4 ACTN1 Alpha-actinin-1 0 153.74 0.00019393 4441700.0 26701.0 25558.0 25597.0 29275.0 36540.0 30150.0 33447.0 28676.0 27683.0 23506.0 False True 31220.95193121125 28095.22933306237 26207.329557163073 27634.816660830562 29380.249304584748 28568.880923958404 30278.658024689925 27923.28538473348 28087.811503909343 27767.451726606367 1.1243722412343582 1.011804381967897 0.9438147157036954 0.9952233619749588 1.0580823041976524 1.028862180269287 1.0904370456031929 1.0056120979217475 1.0115372408119112 1.0 14.761107163833431 -4.759604218689883 24.9760374217569 1.0174422350620336 1.1243723763220184 0.43744219598927847 0.03679103411100153 50.10703900819716 681752.6650410094 0.009990699639810877 0.062263116627772695 1.739385243497082e-05 4.759604218689883 0.10693014125998479 LAILGIHNEVSK ddPTM_PC-9_Lapatinib_30min_R1 2 LAILGIHNEVSK 12 0 P12814-4;P12814-3;P12814;P12814-2;H9KV75;H7C5W8 P12814-4 ACTN1 Alpha-actinin-1 0 ; 130.1 0.00013089 13315300.0 114930.0 104567.0 105077.0 103019.0 99897.0 104096.0 90369.0 91975.0 96399.0 91630.0 False True 113291.07712441905 104324.88153607755 96437.97466894964 110595.36092130962 94021.25486505863 99644.05673962792 95047.86464108709 96248.49427124514 85541.52949352736 107468.12341069987 1.0541830780041277 0.970751867857503 0.89736353076905 1.029099210178433 0.8748757480927369 0.9271963962637412 0.8844284390995871 0.8956003996033519 0.7959711845588119 1.0 16.713549273628203 -1.5228787562244328 0.4335623472285427 0.8912255560333585 4.045638919729469 0.3511035220342549 0.0608444685907259 88.32006353073116 1.1020490086140926 0.03844706162818193 243.95947033454522 0.02999999924400869 1.5228787562244328 3.1544133636961105 LAIQGPEDS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 2 LAIQGPEDSPSR 12 0 Q15773 Q15773 MLF2 Myeloid leukemia factor 2 1 LAIQGPEDS(0.903)PS(0.097)R;LAIQGPEDS(0.5)PS(0.5)R 191.63 6.9748e-05 234331700.0 203720.0 209251.0 379072.0 418744.0 367114.0 337912.0 266247.0 371002.0 285689.0 324318.0 True False 268498.72236076393 276887.29362367006 374045.25759875507 322209.04033030826 316146.557948907 316782.30922186543 289942.46721121704 313672.165677831 300789.937294347 312963.72553471697 0.8579228212535431 0.8847264747714509 1.1951712836996577 1.0295411705615247 1.0101699722827366 1.0122013619329977 0.9264411289705644 1.0022636493795043 0.9611015998113828 1.0 18.255635923850555 -5.032568822840183 24.991123471120346 1.0157061970649837 0.8646235620868973 0.4388518459228723 0.06623009778965856 508.66425172452455 390315.4147935025 0.017468397884511037 0.046301960685434455 9.277504574488304e-06 5.032568822840183 -0.15108263497808638 LAIQGPEDS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LAIQGPEDSPSR 12 0 Q15773 Q15773 MLF2 Myeloid leukemia factor 2 1 LAIQGPEDS(0.5)PS(0.5)R;LAIQGPEDS(0.715)PS(0.285)R 162.64 7.509199999999999e-05 235659000.0 358430.0 378202.0 354167.0 411370.0 485780.0 378081.0 366271.0 384615.0 361047.0 289943.0 True False 419105.11968480767 415747.3951100574 362611.6844658269 388322.2725795351 390594.8962009081 358253.76678643795 331575.15930759814 374519.26378327847 366326.6293411835 342507.3707124746 1.2236382499243637 1.2138348854952548 1.0586974630984782 1.1337632582088892 1.1403985128506962 1.0459738896748647 0.9680818214739858 1.0934633698662122 1.0695437840626925 1.0 18.385775509446958 -1.5228787452805561 0.2944339587032237 1.0226454236955276 2.8248322843503098 0.6397677253423546 0.04791691345555487 36.045156075323035 0.5126056284008588 0.05279797602344908 33.99562594258188 0.029999999999984903 1.5228787452805561 1.8021868606547822 LAIQGPEDS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 2 LAIQGPEDSPSR 12 0 Q15773 Q15773 MLF2 Myeloid leukemia factor 2 1 LAIQGPEDS(0.72)PS(0.28)R;LAIQGPEDS(0.947)PS(0.053)R 169.98 5.949e-05 450140000.0 398463.0 351809.0 410256.0 343060.0 333042.0 315047.0 298492.0 305886.0 367236.0 264317.0 True False 392780.8445508353 350994.4078755809 376526.3353139572 368289.7768146116 313453.12434576463 301573.17422042676 313946.45522742695 320098.5802517435 325874.0145134812 310003.8412697355 1.267019282541971 1.1322259957746117 1.2145860314883654 1.1880168171663439 1.0111265817284758 0.9728046368239252 1.0127179519503469 1.0325632706377486 1.051193472889702 1.0 18.24192656653782 -6.25233043383074 6.443447757616012 1.0126701226426962 1.1972822829896734 0.8652944689730515 0.03615675809276153 0.052756891229209534 11.232046083872387 0.010806565286765733 0.01332959722651732 5.59331870776861e-07 6.25233043383074 0.18461216034697725 LAIQGPEDSPS(ph)R ddPTM_PC-9_AZD4547_30min_R2 3 LAIQGPEDSPSR 12 0 Q15773 Q15773 MLF2 Myeloid leukemia factor 2 1 LAIQGPEDS(0.226)PS(0.774)R;LAIQGPEDS(0.044)PS(0.956)R;LAIQGPEDS(0.208)PS(0.792)R 204.67 9.0061e-08 566050000.0 312593.0 291277.0 408986.0 611749.0 448114.0 479717.0 376146.0 463535.0 395343.0 425141.0 True False 411991.0716616833 385426.59401781426 403562.5784132952 470719.7194778334 385901.1061106824 449720.22015490907 409622.2653086439 391906.3167246366 416240.0238712688 410256.9429928482 1.0042269331414224 0.9394761029663626 0.9836825075263389 1.147377826305402 0.9406327246908034 1.0961916131733784 0.9984529751536335 0.955270406554627 1.0145837407035057 1.0 18.64616822386524 -5.5400053315372855 24.99814991626475 1.0222744466438567 0.9692833783664591 0.1129492755445991 0.059583388108524864 460.4362849341411 672055.4471455815 0.015812452452444354 0.02739641178814753 2.8839960980552772e-06 5.5400053315372855 -0.052991068277397635 LAIQGPEDSPS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LAIQGPEDSPSR 12 0 Q15773 Q15773 MLF2 Myeloid leukemia factor 2 1 LAIQGPEDS(0.044)PS(0.956)R;LAIQGPEDS(0.101)PS(0.899)R;LAIQGPEDS(0.379)PS(0.621)R;LAIQGPEDS(0.227)PS(0.773)R;LAIQGPEDS(0.193)PS(0.807)R;LAIQGPEDS(0.023)PS(0.977)R 184.0 6.8945e-05 344733000.0 419978.4 391963.0 456970.0 517682.0 554021.0 465425.0 492005.0 396049.1 467193.4 357556.2 True False 491072.44816849596 430874.49624677596 467865.8978683746 488677.9558876899 445464.5621230259 441017.2936661141 445398.7245922674 385653.2307737076 474025.21963192214 422378.30864667834 1.1626365230305438 1.0201151134567488 1.1076939518211548 1.1569674528349692 1.054657762966846 1.0441286511117391 1.0545018895959588 0.9130516953139953 1.1222764283296724 1.0 18.688176221037985 -6.707536826963355 1.988258992691087 1.0183099621755902 1.1044958918815317 0.28970355828173144 0.061388202707932465 0.428581756068721 3.4866225747764146 0.02349127744938811 0.022386813146313578 1.9609348866049398e-07 6.707536826963355 0.08618592970594152 LAIQGPEDSPS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 5 LAIQGPEDSPSR 12 0 Q15773 Q15773 MLF2 Myeloid leukemia factor 2 1 LAIQGPEDS(0.012)PS(0.988)R;LAIQGPEDS(0.01)PS(0.99)R;LAIQGPEDS(0.028)PS(0.972)R;LAIQGPEDS(0.422)PS(0.578)R;LAIQGPEDS(0.296)PS(0.704)R 199.33 6.979199999999999e-06 438935500.0 454361.0 431657.0 430517.0 406644.0 402529.0 379264.0 356793.0 378478.0 409945.0 313937.0 True False 447881.7288203977 430657.52473742684 395121.5541036775 436549.9562846183 378853.0356224626 363043.7628275653 375265.99573844275 396063.469581868 363772.6771877728 368200.592155242 1.2164068672425172 1.169627463705576 1.073114933875731 1.1856307827461576 1.0289310872773645 0.9859945110422244 1.019189006573411 1.0756730923856808 0.9879741774950697 1.0 18.49013242132763 -5.477654330428032 0.5861968219967028 1.0088637529460691 1.2568861521887684 0.7055688876651315 0.04459541801335015 1.1299883691021642 0.5113831999080005 0.027753693256929984 0.171967207253077 3.3292443361059042e-06 5.477654330428032 0.2480223992426993 LALAGEGEACPLLGS(ph)PGAGR ddPTM_PC-9_AZD4547_30min_R2 1 LALAGEGEACPLLGSPGAGR 20 0 Q96F46-2;Q96F46 Q96F46-2 IL17RA Interleukin-17 receptor A 1 LALAGEGEACPLLGS(1)PGAGR 122.49 8.365199999999999e-06 1802600.0 11163.0 16315.0 13022.0 18876.0 19559.0 13550.0 15696.0 19755.0 11169.0 12503.0 True False 14712.60179517578 21588.50469278605 12849.319771576347 14524.42983129287 16843.57046291528 12702.716357975652 17092.913592818957 16702.31867473911 11759.370538034578 12065.273775617014 1.219417152796716 1.7893091441003808 1.064983688769983 1.2038209908378226 1.3960371539148024 1.0528328319948166 1.4167033347691136 1.3843298532100619 0.9746459762727769 1.0 13.55857303196542 -2.3432495661497343 0.03303599328484457 1.6194872405298707e-08 3.054932930276786 0.19911735301900924 0.21412902898885997 1636.609353388338 4.780118302193248 143.3641014470872 334.8479423581534 0.004536808352634461 2.3432495661497343 3.0549329140819133 LALAGEGEACPLLGS(ph)PGAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LALAGEGEACPLLGSPGAGR 20 0 Q96F46-2;Q96F46 Q96F46-2 IL17RA Interleukin-17 receptor A 1 LALAGEGEACPLLGS(1)PGAGR 111.77 0.001049 0.0 7003.0 6272.6 5721.1 6224.4 10722.0 5394.5 6601.3 5496.4 7271.1 6829.5 True False 8188.469584445241 6895.302273830773 5857.512721392574 5875.667047777074 8621.101068521013 5111.602923525494 5975.977074726754 5352.1253239171865 7377.426081930252 8067.634287707745 1.0149777856095443 0.8546870157881107 0.7260508486753516 0.7283011150777542 1.0686033552185872 0.6335937824194374 0.7407347509333752 0.6634070327248168 0.9144472615932617 1.0 12.977929971579153 -6.799833034979793 24.999998710740865 0.7662933715733687 0.8603845989900959 0.06653078201242701 0.14428957256581468 427.52109122471484 278377.0710888576 0.050378851348274356 0.04443080018388851 1.5855026236386177e-07 6.799833034979793 0.09409122741672715 LALDGETLGEEEQEDEQPPWAS(ph)PSPTSR ddPTM_PC-9_AZD4547_30min_R2 1 LALDGETLGEEEQEDEQPPWASPSPTSR 28 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 LALDGETLGEEEQEDEQPPWAS(0.418)PS(0.372)PT(0.116)S(0.094)R 67.571 0.00013263 1964900.0 1281.4 1248.9 1482.4 3032.0 3425.7 1329.5 2360.1 2742.0 2502.9 1227.1 True False 1688.858545224243 1652.5825014293903 1462.7424074170476 2333.019243933036 2950.1006868862855 1246.3661548286816 2570.144327880481 2318.286904891657 2635.198184228378 1184.1396025001718 1.426232634782602 1.3955976963697154 1.2352786819464856 1.9702231383927533 2.49134534531021 1.052550013695282 2.170474091444896 1.9577817514057179 2.2254117493110326 1.0 10.209623460191546 -5.763914305682237 24.996435425986956 1.8864795990655316 1.3566924236157099 0.18762626120989345 0.45561640072258025 95.01113177140198 959616.2409222482 0.12212184348640269 0.1910678247921511 1.722208364961512e-06 5.763914305682237 -0.5297871754498218 LALEDSENTAST(ph)NCDSSSEGLEKDTATQR ddPTM_PC-9_AZD4547_30min_R2 1 LALEDSENTASTNCDSSSEGLEKDTATQR 29 1 Q49AR2 Q49AR2 C5orf22 UPF0489 protein C5orf22 1 LALEDS(0.001)ENT(0.012)AS(0.152)T(0.443)NCDS(0.31)S(0.066)S(0.016)EGLEKDTATQR 97.068 8.7616e-11 5526800.0 4136.9 3372.8 4573.4 6743.4 7289.1 5084.2 5266.8 4216.7 5619.1 6598.9 True False 5452.3481471345185 4462.991641301182 4512.753727793522 5188.813314491432 6277.134284024529 4766.284170274527 5735.534996856454 3565.1059051264197 5916.114154379988 6367.874519548836 0.8562273220673979 0.7008604876870886 0.7086750396760724 0.8148422677868752 0.985750310367181 0.7484890218301944 0.9006984951177739 0.5598580647564342 0.9290563336664405 1.0 12.636596192181804 -8.510625429063985 24.683463969697012 1.000000063420631 0.7867010282917247 0.3037833120686704 0.1116317225874523 598.910970922251 1206464.7615485683 0.1061646683835935 0.027411599564004248 3.0858482897560397e-09 8.510625429063985 -0.21329903512890624 LALEDSENTASTNCDS(ph)SSEGLEKDTATQR ddPTM_PC-9_Lapatinib_30min_R1 2 LALEDSENTASTNCDSSSEGLEKDTATQR 29 1 Q49AR2 Q49AR2 C5orf22 UPF0489 protein C5orf22 1 LALEDS(0.009)ENT(0.224)AS(0.177)T(0.063)NCDS(0.364)S(0.12)S(0.042)EGLEKDT(0.001)ATQR;LALEDS(0.023)ENT(0.039)AS(0.099)T(0.254)NCDS(0.437)S(0.116)S(0.032)EGLEKDTATQR 81.06 8.8195e-07 7552800.0 16677.6 21329.0 28047.6 23910.3 21153.7 21800.6 18462.2 23139.9 22268.6 18546.4 True False 16439.77436570273 21279.614010949845 25741.63459486693 25668.74322442259 19909.480955774357 20868.239157680735 19418.082379761607 24215.064230358133 19760.47576924621 21752.120528475407 0.7557780099729424 0.9782776802423925 1.1834080526157853 1.180057051946728 0.9152891981134035 0.9593657377156588 0.8926983626420081 1.113227751687865 0.9084390527984635 1.0 14.408868430018508 LALLEEAR ddPTM_PC-9_Lapatinib_30min_R1 1 LALLEEAR 8 0 B1AKD8;Q5TZA2-2;Q5TZA2 B1AKD8 CROCC Rootletin 0 90.37 0.043891 5878800.0 36783.0 34904.0 43461.0 32761.0 36988.0 41761.0 46645.0 32493.0 40727.0 36280.0 False True 36258.46767482393 34823.18193249535 39887.80434431155 35170.353227492276 34812.438561205934 39974.97937964571 49060.049864262146 34002.74340152839 36139.89638567715 42550.9496599387 0.852118882530157 0.8183878905358728 0.9374127878011975 0.8265468458064713 0.8181354080090368 0.9394615090643149 1.1529719138196275 0.7991065692604655 0.8493323104302537 1.0 15.376903710153877 -6.818574135332749 8.071675422425841 0.9488804668522031 0.8523200246051778 0.21531541500489026 0.09321989063657592 0.45637460685710013 56.94280321492058 0.03436605106685188 0.030399707820942833 1.5185387009275231e-07 6.818574135332749 -0.09656044224702531 LALPGFS(ph)TPR ddPTM_PC-9_Lapatinib_30min_R1 1 LALPGFSTPR 10 0 H0YBF7;A0A0A0MRE5;Q9ULH1;Q9ULH1-2;H0YBM4 H0YBF7 ASAP1 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 1 LALPGFS(0.5)T(0.5)PR 83.883 0.03331 0.0 33195.0 35045.0 37080.0 36539.0 34394.0 32461.0 32725.0 28344.0 37803.0 28915.0 True False 32721.633212782555 34963.8554556584 34031.42553293921 39226.19995053082 32371.012541205717 31072.718700286885 34419.34037534526 29660.965714859216 33545.228056762186 33912.91922318434 0.9648722068848803 1.0309892588590719 1.0034944296294568 1.1566742365167457 0.9545333543293286 0.9162501905481563 1.0149329861233152 0.8746214243503312 0.9891577848547233 1.0 15.049547356408844 -6.458251256199213 24.999880767535835 0.9525115547359664 1.0383614310086615 0.3030728501468617 0.059619573508928735 239.7698301518456 92749.88625317405 0.017953432857877878 0.020357265792471973 3.4813584667539915e-07 6.458251256199213 0.08584987627269514 LALPGFST(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 LALPGFSTPR 10 0 H0YBF7;A0A0A0MRE5;Q9ULH1;Q9ULH1-2;H0YBM4 H0YBF7 ASAP1 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 1 LALPGFS(0.092)T(0.908)PR;LALPGFS(0.451)T(0.549)PR 95.775 0.014149 6991800.0 46064.0 53773.0 57219.0 73752.0 67567.0 65871.0 59677.0 89808.0 66222.0 67148.0 True False 60711.39380927862 71154.07066167235 56460.238673769556 56749.615857041266 58186.48834131588 61752.075956916204 64988.13739033236 75930.23718253468 69722.35972510754 64797.16895826046 0.9369451595699541 1.0981046210137164 0.8713380473480069 0.8758039397307145 0.8979788666198844 0.9530057709264155 1.0029471724635828 1.1718141147716756 1.0760093511187143 1.0 15.983643161500387 -7.529113920690954 4.420435230052597 1.0937163158597074 0.9402191868843518 0.44342212710492024 0.07161808733917724 0.1816218788354643 8.912008995933483 0.03556772008417207 0.020999136523864464 2.9572366458926702e-08 7.529113920690954 -0.1534971289753556 LALPGHAESYNPPPEYLLS(ph)EEER ddPTM_PC-9_Lapatinib_30min_R1 1 LALPGHAESYNPPPEYLLSEEER 23 0 Q14137;Q14137-2 Q14137 BOP1 Ribosome biogenesis protein BOP1 1 LALPGHAESYNPPPEY(0.001)LLS(0.999)EEER 130.69 4.7887e-07 2866400.0 8940.2 5302.9 8825.5 6545.9 8680.4 9376.8 5963.0 6628.2 6629.5 5670.7 True False 8812.71110856811 5290.621460859205 8099.901457415188 7027.3073224822665 8169.835938323019 8975.776122388406 6271.7349628169195 6936.170369433743 5882.815898270106 6650.872939267208 1.3250457780567815 0.7954777529462359 1.2178704256388386 1.056599244437909 1.2283855086281608 1.3495636143332121 0.9429942535495105 1.0428962382489853 0.8845178598342421 1.0 12.699327994072888 LAMQEFMILPVGAANFR ddPTM_PC-9_Lapatinib_30min_R1 2 LAMQEFMILPVGAANFR 17 0 P06733;A0A2R8Y6G6;P06733-2;K7EM90 P06733 ENO1 Alpha-enolase;Enolase 0 ; 182.25 3.1216000000000003e-06 29179000.0 96243.0 75758.0 100578.0 76366.0 93546.0 97245.0 79305.0 81933.0 98520.0 86432.0 False True 94870.55717119554 75582.58700555754 92308.86508230743 81982.21038950807 88043.80819851221 93086.05803916679 83411.0248576548 85739.90629112188 87423.64013840737 101371.65603659954 0.935868672570005 0.7455988188480315 0.9105983732669806 0.8087291220724356 0.8685249076598354 0.9182651411510798 0.8228239344096325 0.8457976286800136 0.8624071417640022 1.0 16.629294799246964 -8.610253281000075 14.34189978709166 1.0000000003681426 0.8547300715336704 0.385499660910156 0.05390292209561607 348.33732614248106 57178.93928374004 0.04811181281510444 0.01242286143922151 2.453277744226329e-09 8.610253281000075 -0.1452699288344722 LANQDEGPEDEEDEVPKKQNS(ph)PVAPTAQPK ddPTM_PC-9_Lapatinib_30min_R1 1 LANQDEGPEDEEDEVPKKQNSPVAPTAQPK 30 2 Q6P1N0;Q6P1N0-2 Q6P1N0 CC2D1A Coiled-coil and C2 domain-containing protein 1A 1 LANQDEGPEDEEDEVPKKQNS(0.999)PVAPT(0.001)AQPK 73.107 6.2438e-06 7418800.0 68154.0 40142.0 47810.0 43466.0 40405.0 37151.0 30717.0 30107.0 37175.0 31020.0 True False 67182.11146208705 40049.05366531714 43879.24635193702 46662.63463832543 38028.45733928638 35562.13833321084 32307.37596056471 31505.88113100714 32987.96002989534 36381.765668448155 1.8465874381778642 1.1008001653984982 1.2060779774080894 1.2825830132481253 1.0452614555831277 0.9774714800071362 0.8880101162485103 0.8659799916838672 0.9067168518020533 1.0 15.150927940661447 -1.5228787452803376 0.5027223853850185 0.9310080943732633 26.416409017786236 0.7889444740918983 0.1271180453575864 52.01212000497561 0.5485325159719363 0.07289231380921034 1401.7734839657492 0.029999999999999995 1.5228787452803376 25.485400923412975 LAPAT(ph)SYDGK ddPTM_PC-9_AZD4547_30min_R2 1 LAPATSYDGK 10 0 Q86V87 Q86V87 FAM160B2 Protein FAM160B2 1 LAPAT(0.975)S(0.025)YDGK 117.14 0.0024014 4954700.0 28220.0 41302.0 41929.0 61159.0 44023.0 62690.0 43678.0 60017.0 42337.0 33736.0 True False 37193.37298753563 54652.063795369286 41372.994064078106 47059.73744713074 37911.166342293574 58769.984389778176 47565.25738450216 50742.75170345828 44574.847387301474 32554.912908439204 1.1424811085239917 1.6787654738649858 1.2708679080309562 1.4455494806417206 1.1645298038093006 1.8052569993066467 1.4610777033340436 1.5586818446165844 1.3692202928838535 1.0 14.990587658540898 -8.558469850678941 18.850393602110238 0.9999999906065618 1.4479869416585547 0.3025982354029212 0.1995956439907893 525.394373623427 278270.01513589197 0.18297806970139252 0.047244734442555635 2.763949789711337e-09 8.558469850678941 0.44798695105199293 LAPAT(ph)SYDGK ddPTM_PC-9_Lapatinib_30min_R1 2 LAPATSYDGK 10 0 Q86V87 Q86V87 FAM160B2 Protein FAM160B2 1 LAPAT(0.617)S(0.383)YDGK;LAPAT(0.5)S(0.5)YDGK 115.0 0.0028372 8248100.0 93820.0 103041.0 89421.0 55985.0 89881.0 90990.0 116382.0 105762.0 95821.0 75810.0 True False 92482.10959551913 102802.41489532022 82069.15055504203 60102.32366048515 84594.376292845 87098.5698080497 122407.69049850057 110676.0886231631 85028.62994013722 88913.65748952441 1.040133903010515 1.1562049947999513 0.9230207470062877 0.6759627863420898 0.9514216227446465 0.9795859518917152 1.3767029043082875 1.2447591489103087 0.9563056153679775 1.0 16.440117419291283 -7.031924907306372 23.498625353711105 1.1667394692597421 0.9463213688577551 0.2555940901295314 0.15772469516749263 427.23320145240757 314467.26280951686 0.06406789347895592 0.04969098741038848 9.291270257528284e-08 7.031924907306372 -0.22041810040198706 LAPDYDALDVANK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LAPDYDALDVANK 13 0 P62750;H7BY10;K7EJV9;K7ERT8;A8MUS3;K7EMA7 P62750 RPL23A 60S ribosomal protein L23a 0 ; 146.16 0.00047062 7088000.0 34122.0 25937.0 28915.0 35578.0 49659.0 37883.0 35394.0 29833.0 33287.0 29566.0 False True 39898.180659780155 28511.853948338612 29604.443260748154 33584.6800054323 39928.67543011424 35896.34879078995 32041.224089630614 29049.915360676318 33773.75940218294 34926.08175567277 1.1423606271923075 0.816348485575759 0.8476313910002153 0.9615931223082992 1.1432337503369938 1.027780586494206 0.9174010504177558 0.8317542048918203 0.9670068242538353 1.0 15.092017180062516 -10.391269073274694 0.0026037229614822256 0.6845270431636555 1.2268911207215554 0.0 0.11168813899340631 4450635.116267202 2319.6989483640873 245157.48585310785 238069.33504485947 4.061915894577084e-11 10.391269073274694 0.5423640775578998 LAPDYDALDVANK ddPTM_PC-9_Lapatinib_30min_R1 3 LAPDYDALDVANK 13 0 P62750;H7BY10;K7EJV9;K7ERT8;A8MUS3;K7EMA7 P62750 RPL23A 60S ribosomal protein L23a 0 ;; 204.17 4.5689e-09 27442800.0 126087.0 121571.0 138928.0 122507.0 127482.0 113368.0 137754.0 108057.0 114134.0 119687.0 False True 124288.97625847625 121289.5098187997 127505.87611758866 131516.5734513722 119983.75939925518 108519.51491371555 144886.22808450123 113077.72270147267 101279.02703569812 140374.7384770969 0.8854084260948052 0.8640408604471874 0.9083249415163978 0.9368963025553921 0.854738970137646 0.7730701128353038 1.0321388994654506 0.8055418227541138 0.7214904058554844 1.0 17.098923809275355 -6.323224056245988 24.959319561297487 0.8585845430579275 0.8968843219105322 0.03050364613399581 0.09055248397241306 919.7374321389104 371545.92119648366 0.028153174672338573 0.03192270713372365 4.750900596722939e-07 6.323224056245988 0.038299778852604716 LAPGGHVGR ddPTM_PC-9_AZD4547_30min_R2 4 LAPGGHVGR 9 0 P36578;H3BM89 P36578 RPL4 60S ribosomal protein L4 0 ;;; 159.2 0.00010482 21121300.0 92426.0 92351.0 124574.0 161851.0 145683.0 124312.0 111206.0 136613.0 101451.0 119938.0 False True 121815.54541977234 122201.65472776495 122922.06736479442 124538.75252302295 125457.43012162595 116538.75098838896 121103.1185654325 115502.5999044362 106813.49274367854 115739.00712628581 1.0525020772543545 1.0558381116439643 1.0620625700605069 1.076030939051823 1.0839684323949326 1.0069098904678742 1.046346617033735 0.9979574110084454 0.9228824006337948 1.0 16.82051564746851 -7.732384632656096 1.515525390181479 0.9607427341746777 1.0603134732638566 0.6740362635268815 0.02643154545560372 0.2327431130138017 1.0058138411506299 0.02042074064447274 0.008145592593534123 1.8518907709244833e-08 7.732384632656096 0.0995707390891789 LAPGGHVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LAPGGHVGR 9 0 P36578;H3BM89 P36578 RPL4 60S ribosomal protein L4 0 ;;;;; 134.81 0.00091821 22964800.0 100363.0 101620.90000000001 127285.5 121074.8 138402.0 111971.5 126971.8 115571.4 103217.5 85246.0 False True 117352.47364039367 111709.15136286843 130320.46905294668 114291.37148579753 111283.1216270702 106099.5174254398 114944.11190777444 112537.77320802007 104726.86066917474 100700.4249930353 1.165362247959828 1.109321548251604 1.2941402090602891 1.1349641423430161 1.1050908835267261 1.0536153887411888 1.1414461449961535 1.1175501316484362 1.0399842967536426 1.0 16.61971024650098 -6.13989321171373 3.4525756585030547 1.0838953991992608 1.1849646329253916 0.428402597925708 0.05781102631713052 0.26112881589660936 5.739897796425696 0.017541316926339718 0.023442146951263475 7.246141128948856e-07 6.13989321171373 0.10106923372613075 LAPGGHVGR ddPTM_PC-9_Lapatinib_30min_R1 3 LAPGGHVGR 9 0 P36578;H3BM89 P36578 RPL4 60S ribosomal protein L4 0 ;; 132.08 0.001018 31109200.0 84767.0 79791.0 91152.0 87580.0 82976.0 81278.0 73946.0 70998.0 80057.0 68500.0 False True 83558.20703563599 79606.24884184447 83657.83441689507 94020.92535831565 78095.5148170926 77801.9294082719 77774.5620594433 74296.82627094194 71040.13762241656 80340.1337294873 1.0400556130138425 0.9908652767480587 1.0412956829096 1.1702858956507698 0.9720610508322959 0.968406770024036 0.9680661264682168 0.9247784739954039 0.8842422127602539 1.0 16.293833242360606 -6.500423284146364 24.51215404699247 0.9483218241460973 1.0563759693173036 0.5214198516477484 0.0508775525577441 524.3413942225908 572366.3540378016 0.016649404376995667 0.018724579852865963 3.1591970548093787e-07 6.500423284146364 0.10805414517120626 LAPLT(ph)TPKPR ddPTM_PC-9_AZD4547_30min_R2 1 LAPLTTPKPR 10 1 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 LAPLT(0.845)T(0.155)PKPR 65.241 0.035552999999999994 8513900.0 15967.0 17756.0 19380.0 22466.0 22529.0 24260.0 20426.0 24849.0 25456.0 19593.0 True False 21044.173865768305 23495.279762495204 19123.008537332957 17286.810796239955 19401.23722884699 22743.018364906973 22243.874429594798 21009.158023214 26801.55219054599 18907.05503364506 1.1130328773212035 1.2426726277934563 1.0114218477337484 0.9143047801721693 1.0261374494506168 1.2028852893502358 1.1764854119275516 1.1111808785571444 1.4175424011223687 1.0 14.206637045892284 -6.766887086836166 24.98880771705248 1.188246783130646 1.0606171073546842 0.1875887661361102 0.12458453222658591 233.1091675100329 1069271.8554479585 0.044411649404389936 0.040280430045979296 1.7104599634791526e-07 6.766887086836166 -0.12762967577596185 LAPPS(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LAPPSPAR 8 0 O75145-2;O75145 O75145-2 PPFIA3 Liprin-alpha-3 1 LAPPS(1)PAR;LAPPS(1)PAR;LAPPS(1)PAR 104.42 0.0038583 75182300.0 34541.8 30748.9 98798.0 64822.1 90921.0 79871.0 67548.0 55923.0 59911.5 49213.100000000006 True False 40389.04450835219 33801.447579599415 101153.71901350126 61190.32789308369 73105.68273185966 75682.42415514032 61149.364434829986 54455.080505316306 60787.592346077516 58135.04545931473 0.6947452124487988 0.5814297952730603 1.7399783248521368 1.0525549160515781 1.2575148458948398 1.3018382209420645 1.051850290159742 0.9366997148634929 1.0456273297080183 1.0 15.827120503038456 -5.191461905266462 24.99963617413866 1.1699554603975162 0.638085232520052 0.4868627783180537 0.21974741396901554 136.62062768271912 48807.080082565306 0.05575296465501266 0.14750852343653612 6.434845066390522e-06 5.191461905266462 -0.5318702278774642 LAPPS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 2 LAPPSPAR 8 0 O75145-2;O75145 O75145-2 PPFIA3 Liprin-alpha-3 1 LAPPS(1)PAR;LAPPS(1)PAR 104.42 0.0038583 68024700.0 66264.0 52576.0 65298.0 58253.0 61443.0 59630.0 56387.0 42388.2 60168.0 39891.9 True False 65319.06320867062 52454.26350225978 59929.4504975692 62537.11994631135 57829.043541585765 57079.76390431921 59306.44295629004 44357.71051773197 53391.24624287138 46787.16176238451 1.396089455915345 1.121125144727874 1.280895190905782 1.3366299127934993 1.236002385339788 1.2199877435226183 1.2675794111531395 0.9480744043207651 1.141151637152659 1.0 15.513825093062197 -7.748958571331171 24.998947621835367 1.0334597734229254 1.2603680417865142 0.6371457493206252 0.08144333247407988 133.14741176897311 266694.3465829061 0.03669693991131315 0.020997024176780135 1.7825488020786456e-08 7.748958571331171 0.2269082683635888 LAPS(ph)EDELTCFSK ddPTM_PC-9_AZD4547_30min_R2 1 LAPSEDELTCFSK 13 0 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4;A8MV73 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 LAPS(0.977)EDELT(0.023)CFSK 175.88 0.00015946 9333000.0 12153.0 15560.0 17461.0 26933.0 20146.0 14877.0 18152.0 20730.0 16600.0 19757.0 True False 16017.401201896539 20589.465707615753 17229.45573118528 20724.012960701988 17349.07564527283 13946.738838199544 19767.492834916506 17526.654828010218 17477.442110428325 19065.31344356278 0.8401331165790332 1.0799437296724639 0.9037069221121377 1.0870009046559501 0.9099811391315248 0.7315242353336985 1.0368302044145417 0.9192953936945591 0.9167141239070169 1.0 14.218662629457242 LAPS(ph)EDELTCFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LAPSEDELTCFSK 13 0 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4;A8MV73 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 LAPS(1)EDELTCFSK;LAPS(1)EDELTCFSK 131.35 6.9363e-05 4371100.0 17496.9 20014.9 19248.3 22244.4 24919.7 23272.9 23027.1 22400.8 17427.9 15580.5 True False 20458.779590472637 22001.846998134057 19707.252471584252 20998.118385317826 20036.86367256325 22052.42815440106 20845.806386233075 21812.8027356095 17682.75006715246 18405.121314829867 1.1115808062611379 1.1954198302624683 1.070748306108974 1.1408845411086022 1.0886569737749359 1.1981680412305888 1.1326090184168813 1.185148544390952 0.9607516171547668 1.0 14.167819638629023 -8.267078948183617 24.98903162961515 0.9803757835083746 1.1398711639757355 0.6999957998311604 0.04190395872026564 256.5861292221012 1136918.5751578931 0.03492892334210928 0.010026063636166276 5.4065603090354134e-09 8.267078948183617 0.1594953804673609 LAPS(ph)EDELTCFSK ddPTM_PC-9_Lapatinib_30min_R1 1 LAPSEDELTCFSK 13 0 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4;A8MV73 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 LAPS(0.955)EDELT(0.04)CFS(0.006)K 138.31 6.3485e-05 6816600.0 14756.0 17836.0 22912.0 20995.0 18541.0 23673.0 17434.0 17001.0 17589.0 15160.0 True False 14545.576734081022 17794.701837840566 21028.26380287766 22539.042337266863 17450.454833008524 22660.560974458305 18336.647214782854 17790.928525201856 15607.94159961881 17780.38580056976 0.8180686795679608 1.0008051589786284 1.1826663402435185 1.2676351677669793 0.9814441052482302 1.2744695884907158 1.0312851149830096 1.0005929412753103 0.8778179379616536 1.0 14.117999007796447 -7.774617582617651 2.890708979597045 0.943210596274788 1.0940235160576481 0.1534827877584316 0.13357628795539503 0.48064139981924775 8.112799332196358 0.08546326774412968 0.03862350361462458 1.680282937624448e-08 7.774617582617651 0.15081291978286016 LAPT(ph)PTEGK ddPTM_PC-9_Lapatinib_30min_R1 1 LAPTPTEGK 9 0 Q8IY33-4;Q8IY33-2;Q8IY33;Q8IY33-5 Q8IY33-4 MICALL2 MICAL-like protein 2 1 LAPT(0.976)PT(0.024)EGK 84.198 0.019821000000000002 0.0 50021.0 54290.0 55888.0 50396.0 63354.0 49538.0 49827.0 47299.0 51456.0 44214.0 True False 49307.691367272084 54164.29484056768 51293.10437391873 54102.28995612773 59627.642278756364 47419.375218718174 52406.79825461659 49496.68421348879 45660.48342429845 51856.330988548216 0.9508519100235039 1.0445068867778005 0.9891387106667098 1.0433111815811942 1.1498623435569388 0.9144375298975571 1.010615237437256 0.9544964572294843 0.8805189752892846 1.0 15.662232513779989 LAPVPS(ph)PEPQKPAPVS(ph)PESVK ddPTM_PC-9_AZD4547_30min_R2 2 LAPVPSPEPQKPAPVSPESVK 21 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 2 LAPVPS(1)PEPQKPAPVS(0.975)PES(0.025)VK;LAPVPS(1)PEPQKPAPVS(0.984)PES(0.016)VK 92.416 0.0013083 18319000.0 137084.0 118013.0 163933.0 187503.0 185558.0 163612.0 154603.0 152091.0 148640.0 169501.0 True False 180673.8604756677 156158.39438000368 161759.14130808058 144277.0802424722 159796.47466422786 153381.31577572756 168362.36749430327 128588.83065349278 156496.8069454257 163566.82158208912 1.1045874629592474 0.9547070296382364 0.988948368278335 0.8820681287742943 0.9769491949443485 0.9377287783192035 1.0293185736925714 0.7861547311962532 0.9567759856902568 1.0 17.319520611510256 LAPVPS(ph)PEPQKPAPVS(ph)PESVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LAPVPSPEPQKPAPVSPESVK 21 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 2 LAPVPS(1)PEPQKPAPVS(0.987)PES(0.013)VK;LAPVPS(1)PEPQKPAPVS(0.968)PES(0.032)VK;LAPVPS(1)PEPQKPAPVS(0.976)PES(0.024)VK 89.829 0.0013710999999999999 22771100.0 150159.0 162890.0 159719.0 194167.0 195249.0 178700.0 200141.0 172922.0 183658.0 142016.0 True False 175577.9529245625 179060.64269749343 163527.3066976806 183288.45248790766 156991.36005667434 169328.65741662917 181182.19558464084 168382.9807260035 186343.65080320003 167762.37660196255 1.0465871817084673 1.067346840956703 0.9747555441806228 1.0925480206016793 0.9357959945283572 1.0093363055912281 1.0799930190218903 1.0036993045557134 1.1107594836077215 1.0 17.35605967903581 -7.230747392728534 24.605706336798065 1.0489212500858514 1.0204343664575133 0.06381400465023379 0.051658727574249455 1712.8392957030453 1373179.9759503643 0.019102095110124895 0.014794614932862469 5.878311649554703e-08 7.230747392728534 -0.028486883628338067 LAPVPS(ph)PEPQKPAPVS(ph)PESVK ddPTM_PC-9_Lapatinib_30min_R1 2 LAPVPSPEPQKPAPVSPESVK 21 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 2 LAPVPS(1)PEPQKPAPVS(0.967)PES(0.033)VK;LAPVPS(1)PEPQKPAPVS(0.981)PES(0.019)VK 87.15700000000001 0.00063252 7347300.0 92571.0 80356.0 83715.0 80741.0 83855.0 86409.0 73645.0 74766.0 85068.0 74513.0 True False 91250.9205645577 80169.94061905806 76832.27584924518 86678.96248408007 78922.81376527311 82713.48849921713 77457.97775224748 78239.90130670223 75486.74603424719 87392.47276766859 1.0441508024054513 0.9173552147012535 0.8791635413899146 0.9918355636247371 0.9030847997068132 0.9464600998201474 0.8863232186846137 0.8952704830163313 0.8637671374161414 1.0 16.415221403343807 -4.761447538615895 13.037650363294379 0.9172412754700713 1.0442492238681067 0.41628112413082385 0.0438354870892716 0.052049368767413666 775.047831580739 0.010466406048495776 0.05843391340686811 1.7320182403766394e-05 4.761447538615895 0.12700794839803542 LAPVPS(ph)PEPQKPAPVSPESVK ddPTM_PC-9_AZD4547_30min_R2 2 LAPVPSPEPQKPAPVSPESVK 21 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 LAPVPS(1)PEPQKPAPVSPESVK;LAPVPS(1)PEPQKPAPVSPESVK 106.02 3.6972e-05 86953000.0 151937.0 135348.0 201774.0 241212.0 216308.0 193113.0 154292.0 205913.0 155037.0 176757.0 True False 200249.80551407565 179096.5941256027 199098.34492321033 185604.3000882504 186277.36794786394 181037.61358212188 168023.68909679027 174093.87726001273 163231.9393056915 170568.79123064366 1.1740119870070325 1.0499962673911885 1.1672612761498022 1.0881492373201829 1.0920952573087013 1.0613759543932175 0.9850787350048585 1.0206666530491058 0.9569859651814544 1.0 17.37999417703913 -6.964325649581286 1.2098724494725375 0.9853795661070481 1.120228515996442 0.7199908170104601 0.03658415613619242 0.24041645503345158 0.725299932204822 0.019148279733700917 0.01427453557546711 1.0856112880600204e-07 6.964325649581286 0.1348489498893939 LAPVPS(ph)PEPQKPAPVSPESVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LAPVPSPEPQKPAPVSPESVK 21 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 LAPVPS(1)PEPQKPAPVSPESVK;LAPVPS(1)PEPQKPAPVSPESVK;LAPVPS(0.966)PEPQKPAPVS(0.029)PES(0.004)VK;LAPVPS(1)PEPQKPAPVSPESVK;LAPVPS(0.999)PEPQKPAPVS(0.001)PESVK 93.37100000000001 0.0002017 70409700.0 235572.0 219842.0 222127.0 265648.0 294718.0 262134.0 255102.0 240027.0 229480.0 225117.0 True False 275449.68684091547 241666.4608748371 227423.35010133852 250764.6038024356 236970.12355086498 248387.23157946658 230936.89178145883 233726.5455796287 232835.71086649297 265928.930074808 1.0358018842230863 0.9087633331463949 0.8552034937957388 0.9429760189381932 0.8911032112384437 0.9340361408200047 0.8684158271779395 0.8789060502513941 0.8755561525441943 1.0 18.020681209154404 -4.764188383886727 5.6193507839439265 0.900689464024857 1.0417080664442657 0.4665933341414479 0.04132190644342518 0.11513520106094408 12.097096152553085 0.00959351934721871 0.06296264798960352 1.721121842142742e-05 4.764188383886727 0.14101860241940878 LAPVPS(ph)PEPQKPAPVSPESVK ddPTM_PC-9_Lapatinib_30min_R1 2 LAPVPSPEPQKPAPVSPESVK 21 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 LAPVPS(1)PEPQKPAPVSPESVK;LAPVPS(1)PEPQKPAPVSPESVK 104.81 4.2479e-05 60988000.0 208112.0 161674.0 177881.0 151149.0 167252.0 156154.0 147680.0 152972.0 166008.0 128117.0 True False 205144.2847169337 161299.65378622056 163256.31082051684 162265.0016782831 157414.5661900838 149475.65743275316 155326.14779621048 160079.63757174177 147310.43089826158 150261.85274482847 1.3652452766259007 1.0734571073081087 1.086478755840681 1.0798815448777817 1.0476016588015984 0.994767831637146 1.0337031319584624 1.0653378395618858 0.9803581428509408 1.0 17.19711927050966 -2.1002583552490335 1.1480578183065682 1.0326593747558814 199.99998221471373 0.890160765136812 0.03442867952901634 282.3233977744369 0.8349745369753241 0.010550660195848213 147369.2510166258 0.007938558413397467 2.1002583552490335 198.96732283995783 LAPWQAS(ph)PPHPCR ddPTM_PC-9_AZD4547_30min_R2 1 LAPWQASPPHPCR 13 0 Q8IY92;Q8IY92-2 Q8IY92 SLX4 Structure-specific endonuclease subunit SLX4 1 LAPWQAS(1)PPHPCR 132.15 0.00016634 0.0 20235.0 21157.0 25186.0 39715.0 27546.0 24819.0 20519.0 26725.0 19773.0 23563.0 True False 26669.309085853423 27995.58650231532 24852.01718375994 30559.320340633414 23721.713378570712 23267.06400653858 22345.15124942993 22595.26532940536 20818.160412620437 22738.06654201902 1.1728925604369056 1.2312210649300641 1.0929696743491548 1.3439718053494583 1.0432599154696796 1.0232648393187695 0.9827199339106957 0.993719729320443 0.9155642312045013 1.0 14.472821964086076 -6.45651310160462 6.292250918410598 0.9876164770670655 1.2035949166374316 0.7413410491694414 0.06357553117304315 0.11807224291321299 8.887010932347112 0.01924756527083324 0.02166848360440162 3.4953196491320084e-07 6.45651310160462 0.2159784395703661 LAPWQAS(ph)PPHPCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LAPWQASPPHPCR 13 0 Q8IY92;Q8IY92-2 Q8IY92 SLX4 Structure-specific endonuclease subunit SLX4 1 LAPWQAS(1)PPHPCR 103.77 0.00080181 3421000.0 22793.0 24665.0 20542.0 19724.0 26655.0 26103.0 26501.0 21395.0 23379.0 18352.0 True False 26651.404717729598 27113.578194693768 21031.799185968826 18618.928226070784 21432.14409451851 24734.112728294745 23990.633429375066 20833.403919876306 23720.87364627737 21679.07232564792 1.2293609393146885 1.250679816341423 0.970142950309118 0.8588434018942424 0.9886098340639199 1.1409211776572417 1.1066263846074447 0.9609914855641157 1.0941830577415368 1.0 14.404015402854622 -5.256105549956282 24.848597370912096 1.014890968390365 1.2400204086441426 0.5704427328670088 0.07809245231245324 309.5257464247445 1441967.5499397481 0.022169425170615324 0.05515047258586496 5.544909343480771e-06 5.256105549956282 0.22512944025377757 LAPWQAS(ph)PPHPCR ddPTM_PC-9_Lapatinib_30min_R1 2 LAPWQASPPHPCR 13 0 Q8IY92;Q8IY92-2 Q8IY92 SLX4 Structure-specific endonuclease subunit SLX4 1 LAPWQAS(1)PPHPCR;LAPWQAS(1)PPHPCR 127.18 6.8189e-05 14093200.0 66747.0 54485.0 80246.0 53926.0 62966.0 62140.0 57999.0 70105.0 74071.0 46626.0 True False 65795.17554009933 54358.8433300484 73648.48363851786 57891.897931862506 59262.463675918996 59482.41705541503 61001.9044287135 73362.33423088517 65728.34397779097 54685.24197476026 1.2031614593653404 0.994031321195168 1.3467707370209683 1.0586384158011455 1.083701224240195 1.087723394967675 1.1155094542119548 1.3415380746554115 1.2019393460511265 1.0 15.738863921844484 LAQALHEMR ddPTM_PC-9_Lapatinib_30min_R1 2 LAQALHEMR 9 0 P20700;E9PBF6;A0A0D9SFE5 P20700 LMNB1 Lamin-B1 0 ; 128.6 4.4430000000000005e-06 0.0 31978.0 26404.0 32044.0 25818.0 32983.0 31390.0 26527.3 28718.0 29283.0 26762.0 False True 31521.987855953023 26342.86316025694 29409.466013417077 27716.741846323228 31043.004787072983 30047.522873663926 27900.753794924225 30052.343120213343 25984.840176339643 31387.776041876506 1.0042759262044387 0.8392714133397404 0.9369719592168609 0.8830425516399917 0.989015747584552 0.9573001551169328 0.8889050870536347 0.9574537259383565 0.8278649669754095 1.0 14.937915190979163 -4.387275816730013 9.54230870584966 0.9204344540851254 2.654229214156423 0.16832591054363455 0.056201664064233735 20060.060153543785 37583.84754136782 0.013209371738628926 707866.7740436407 4.0994366855985464e-05 4.387275816730013 1.733794760071298 LAQANGWGVMVSHR ddPTM_PC-9_AZD4547_30min_R2 2 LAQANGWGVMVSHR 14 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 ; 125.22 2.4217e-05 13080900.0 39948.0 41709.0 47994.0 67016.0 68849.0 51817.0 43641.0 60613.0 44444.0 55150.0 False True 52650.633029981334 55190.61858605047 47357.5682012775 51566.496586878675 59290.50477024673 48576.874798614335 47524.96445618067 51246.65359817576 46793.219105775686 53219.21528635356 0.9893162224712844 1.0370430734292022 0.889858445797507 0.9689450757478817 1.1140807779901627 0.9127694675173159 0.8930038558529253 0.9629351602130143 0.8792542102321147 1.0 15.699659617627873 LAQANGWGVMVSHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LAQANGWGVMVSHR 14 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 ; 153.14 2.108e-05 18673800.0 83669.0 89397.0 83493.0 99833.0 103178.0 96115.0 102311.0 93780.0 79933.0 82026.0 False True 97832.5091619231 98271.74335580926 85483.78976896564 94239.6806729529 82961.01156947025 91074.56019921257 92619.36141250494 91318.37436812322 81101.86890662079 96896.66448254106 1.0096581722846678 1.0141911889393878 0.8822160208039792 0.9725792025579282 0.8561802618543 0.9399142961791268 0.9558570659487787 0.9424305248874387 0.8369934026081342 1.0 16.564159383504347 -5.245494772632389 24.557912531984545 0.9223383462219433 1.0119247077132372 0.3467978046208797 0.04865420688741226 676.4861639043818 1041919.9792011359 0.011708007947550173 0.030728949902659702 5.6820523069755894e-06 5.245494772632389 0.08958636149129384 LAQANGWGVMVSHR ddPTM_PC-9_Lapatinib_30min_R1 3 LAQANGWGVMVSHR 14 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 ;; 181.76 2.2789e-05 21445000.0 99760.0 71798.0 89000.0 82138.0 84074.0 78022.0 71922.0 73002.0 86972.0 78447.0 False True 98337.40410625657 71631.7561422561 81682.76354993519 88178.70252433559 79128.93261584376 74685.18093816534 75645.7692429512 76393.93942690358 77176.29750423839 92006.45942594305 1.06880978487613 0.7785513820354455 0.8877937925182579 0.9583968677254834 0.8600367094827235 0.8117384518885896 0.8221788960789135 0.8303106097501106 0.8388139048689119 1.0 16.48944753044347 -6.495152945748858 20.327573228093947 0.8462994711042454 0.9103397875896304 0.0987808788627359 0.0842677428740599 156.77019215709507 114937.35708579271 0.02507082886239204 0.028290906997154107 3.1977687512237505e-07 6.495152945748858 0.064040316485385 LAQGHTTVDELAR ddPTM_PC-9_AZD4547_30min_R2 2 LAQGHTTVDELAR 13 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 89.46 0.005116 7456600.0 18201.6 18067.0 22806.0 51884.0 40240.0 32854.0 19657.4 36484.0 26219.0 32287.0 False True 23989.33018320087 23906.804430558714 22503.577538824313 39922.94539980922 34653.370592960346 30799.634186341857 21406.87051857029 30846.23611891581 27604.88281285064 31156.641957397944 0.7699587849037999 0.767310047830177 0.7222722387603451 1.2813622679362522 1.11223060047176 0.988541519604576 0.6870724562628087 0.9900372498773595 0.8860031466355134 1.0 14.927252128594882 LAQGHTTVDELAR ddPTM_PC-9_Lapatinib_30min_R1 1 LAQGHTTVDELAR 13 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 61.167 0.045751 6277700.0 12921.0 13040.0 16841.0 15309.0 16144.0 20664.0 13823.0 17751.0 18684.0 14838.0 False True 12736.744170578797 13009.80668117522 15456.39798813995 16434.87492932692 15194.441660325203 19780.24889013671 14538.68730354155 18575.77626321147 16579.611168757634 17402.72852960778 0.7318820234947293 0.7475728107257003 0.8881594608479654 0.9443849509785652 0.873106859908459 1.1366176778821773 0.8354257367634305 1.0674059663464814 0.9527018214730092 1.0 14.087025899849086 -5.321625450365618 0.9627488888843786 0.9862097884275962 0.6724121969076634 0.5704822985690661 0.08083981279088677 0.7004836187147666 0.8953608100674606 0.027902096951541198 0.19185105995363436 4.76842053560213e-06 5.321625450365618 -0.3137975915199328 LAQT(ph)TPVDSALGSSR ddPTM_PC-9_Lapatinib_30min_R1 2 LAQTTPVDSALGSSR 15 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 LAQT(0.732)T(0.268)PVDSALGSSR;LAQT(0.496)T(0.496)PVDS(0.008)ALGSSR 181.75 2.8230999999999998e-05 26498000.0 82487.0 96735.0 104271.0 79317.0 115660.0 113494.0 120925.0 103171.0 113535.0 92998.0 True False 81310.72025373676 96511.01605088086 95698.24087769951 85150.23677375536 108857.10619630886 108640.12618743593 127185.90480943082 107964.70130425273 100747.49272344762 109072.58038795445 0.7454735183171333 0.8848329773404642 0.8773812862711741 0.7806750007278549 0.9980244879979993 0.9960351703518854 1.1660667085811123 0.9898427351790783 0.9236738726186199 1.0 16.734928944474696 -6.337711443755135 5.5350768599000375 1.0205407941284756 0.8308205126872109 0.6440156504368519 0.06906886642376679 0.1501496533644265 8.14644901454662 0.02243710103631555 0.025605422114498993 4.595032169993988e-07 6.337711443755135 -0.18972028144126474 LAQTTPVDSALGS(ph)SR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LAQTTPVDSALGSSR 15 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 LAQT(0.101)T(0.079)PVDS(0.171)ALGS(0.545)S(0.104)R 76.574 0.013807 3041600.0 10558.0 13628.0 12649.0 11305.0 16599.0 10885.0 13142.0 11107.0 9942.6 8110.2 True False 12345.260869994683 14980.897775685651 12950.600131599627 10671.617501304514 13346.545106918515 10314.171438052643 11897.094620159518 10815.453018839276 10087.9917154488 9580.515059692128 1.2885800808282848 1.5636839650421743 1.3517644981412718 1.1138876599863565 1.393092649378645 1.0765779682813932 1.241801150150463 1.1289009986887732 1.0529696631751841 1.0 13.225887503680847 -6.135434681076326 0.28640804447896206 0.9860120879143341 1.5770500404199292 0.5512582661711611 0.11349217171935004 2.8246411596275327 0.35798636816115526 0.15344604138790136 0.5659704387891817 7.320914232123347e-07 6.135434681076326 0.5910379525055951 LAQYESK ddPTM_PC-9_Lapatinib_30min_R1 1 LAQYESK 7 0 P24534 P24534 EEF1B2 Elongation factor 1-beta 0 86.794 0.030498 0.0 27026.0 34141.0 22370.0 19372.0 25010.0 22483.0 20316.0 14556.0 23680.0 20056.0 False True 26640.604284038593 34061.94861211677 20530.824950697162 20796.681503097592 23538.960971551856 21521.45450043283 21367.863073048553 15232.324899290525 21012.909038545324 23522.65287705983 1.1325510104355407 1.4480487719705823 0.8728107776788897 0.8841129277293078 1.0006932931662622 0.9149246308617407 0.9083951195780001 0.6475598215431584 0.8933052385021545 1.0 14.521763155571932 -5.274631645730082 24.999999985871536 0.8828960972664951 1.2902998844035862 0.6550570617804254 0.11603003021927757 386.9634486926957 733315.1486259538 0.030371671304733637 0.0638262301526418 5.313349139341704e-06 5.274631645730082 0.40740378713709113 LAS(ph)PELER ddPTM_PC-9_AZD4547_30min_R2 4 LASPELER 8 0 P05412;P17535 P05412;P17535 JUN;JUND Transcription factor AP-1;Transcription factor jun-D 1 LAS(1)PELER;LAS(1)PELER;LAS(1)PELER;LAS(1)PELER 105.98 0.0038335 462024000.0 162538.0 141034.0 208971.0 309235.0 274020.0 234138.0 215548.0 238837.0 214868.0 231340.0 True False 214221.70299957736 186620.48242981243 206199.908000774 237945.64838312377 235977.05292949732 219497.31384676808 234731.3544281949 201930.2295782672 226225.48381828412 223240.85701441608 0.9595989993253955 0.8359602490585366 0.9236656352177433 1.0658696242496422 1.0570513663377434 0.9832309227902388 1.0514713012996397 0.9045397526189719 1.0133695365793876 1.0 17.76824156440785 -5.5968821455087285 6.571501969069842 1.0089194654332445 0.8934063100243486 0.46487207416009235 0.05171175259014943 0.17110458577522428 12.031079622912948 0.014168309540001195 0.024788312147607294 2.5299844651694407e-06 5.5968821455087285 -0.11551315540889595 LAS(ph)PELER ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LASPELER 8 0 P05412;P17535 P05412;P17535 JUN;JUND Transcription factor AP-1;Transcription factor jun-D 1 LAS(1)PELER;LAS(1)PELER;LAS(1)PELER;LAS(1)PELER;LAS(1)PELER 117.7 0.0035353000000000003 204990000.0 179842.0 178295.0 208844.0 280551.0 305849.0 274802.0 331097.0 303157.0 284217.0 242973.0 True False 210285.69855858924 195994.94928939518 213823.63300528005 264832.63702861354 245920.0840054169 260390.89935872707 299733.0952253048 295199.44997139217 288373.13593926205 287022.081526791 0.7326464132654579 0.6828566925820332 0.7449727626106757 0.9226908104765233 0.8567984828807063 0.9072155632542226 1.0442858390229022 1.02849038095293 1.0047071445001174 1.0 18.130802206751497 -6.080752733838864 0.6574358694868707 1.0274135629881698 0.6641581344962886 0.8723718328537909 0.045097087414506826 0.3244496035519412 0.279027519191038 0.029337553285311856 0.07028701755395991 8.303233787194609e-07 6.080752733838864 -0.3632554284918812 LAS(ph)PELER ddPTM_PC-9_Lapatinib_30min_R1 5 LASPELER 8 0 P05412;P17535 P05412;P17535 JUN;JUND Transcription factor AP-1;Transcription factor jun-D 1 LAS(1)PELER;LAS(1)PELER;LAS(1)PELER;LAS(1)PELER;LAS(1)PELER 107.21 0.0038138000000000004 406569900.0 169488.0 149476.0 180883.0 138956.0 204164.0 193246.0 197977.0 177978.0 204104.0 189106.0 True False 167071.07003970706 149129.89750577835 166011.49796857178 149175.28778362743 192155.47492186792 184981.31905842814 208227.28035109912 186247.50762063236 181115.6582095966 221792.720132094 0.7532757159035872 0.6723840954606646 0.7484984081970754 0.6725887472536632 0.8663741298967121 0.8340279110525272 0.9388373082177105 0.8397367934786506 0.8165987508594907 1.0 17.758852487358944 -6.273215500536674 22.074982064162896 0.874966394397834 0.7115088222703385 0.6837111059849694 0.05680564384631023 89.56490014344747 167893.68242981413 0.016697613114801467 0.019135272138091172 5.330703159221057e-07 6.273215500536674 -0.16345757212749545 LAS(ph)PMKPVPGTPPSSK ddPTM_PC-9_AZD4547_30min_R2 1 LASPMKPVPGTPPSSK 16 1 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 LAS(1)PMKPVPGTPPSSK 67.418 0.011802 9087300.0 45353.0 39890.0 46499.0 55107.0 50973.0 47810.0 42817.0 53115.0 51087.0 47331.0 True False 59774.3105989973 52783.66240853418 45882.3928780931 42402.93254466283 43896.278808026014 44820.433142052854 46627.63005248022 44907.29721127654 53787.35452382244 45673.956096435184 1.3087176086256 1.1556621523453692 1.0045635806370228 0.9283831787010967 0.9610789727814291 0.9813126992419878 1.0208800383752934 0.9832145285698499 1.1776373040744876 1.0 15.479084135184772 -4.976068786088569 2.3287026421839165 1.0012463512546252 1.3257435350639704 0.6990721181242052 0.0629380599525 0.21611063039519202 1.905059070283912 0.017254820841336043 0.12184521501202694 1.0566501375586034e-05 4.976068786088569 0.3244971838093451 LAS(ph)PQPSYAADANDSK ddPTM_PC-9_AZD4547_30min_R2 2 LASPQPSYAADANDSK 16 0 Q5TGY3 Q5TGY3 AHDC1 AT-hook DNA-binding motif-containing protein 1 1 LAS(0.985)PQPS(0.015)YAADANDSK;LAS(0.999)PQPS(0.001)YAADANDSK 198.67 4.7642e-12 8256200.0 31059.0 32481.0 33703.0 36809.0 38533.0 40946.0 42457.0 46973.0 38803.0 40964.0 True False 40935.11593266723 42979.848049425935 33256.07619885102 28323.253743380956 33183.35807799555 38385.64014713443 46235.59074989261 39714.40218215745 40854.04736210545 39529.862828471196 1.035549152049774 1.0872754159538824 0.8412899468727346 0.7165027074918475 0.8394503725445613 0.9710542207975322 1.1696370146923871 1.0046683529990228 1.0334983336365264 1.0 15.270655328457856 -7.003355010711447 22.890739924035483 1.0549122090466403 0.9007887208638138 0.29984982484406597 0.10647141584873226 64.13415559845113 437586.3039728188 0.042947168451538155 0.03702099460925852 9.923045649982646e-08 7.003355010711447 -0.1541234881828265 LAS(ph)PQPSYAADANDSK ddPTM_PC-9_Lapatinib_30min_R1 2 LASPQPSYAADANDSK 16 0 Q5TGY3 Q5TGY3 AHDC1 AT-hook DNA-binding motif-containing protein 1 1 LAS(1)PQPSYAADANDSK;LAS(0.994)PQPS(0.006)YAADANDSK 181.94 2.2275999999999998e-29 5279700.0 24019.0 34373.0 37571.0 32484.0 39068.0 34095.0 31820.0 41603.0 36086.0 35191.0 True False 23676.484655454846 34293.41143037082 34482.05740825403 34872.981723447345 36770.09705064326 32636.836329326914 33467.48390354426 43536.027259218485 32021.614677573754 41273.71746094001 0.5736455573177153 0.8308776999024838 0.8354483077732612 0.8449198150481576 0.8908840616414351 0.7907413806428574 0.8108667200917073 1.054812358504403 0.7758354867810946 1.0 15.33293576509405 -4.335088419243778 1.5111030372226526 0.8743924123546616 5.959354215092576e-14 0.5291733523946911 0.08481663751405345 2.99459220029873 2.5707525827318274 0.02292792372634127 5.456998570454146 4.622868935195525e-05 4.335088419243778 -0.874392412354602 LAS(ph)PSEVVQQVAEK ddPTM_PC-9_AZD4547_30min_R2 2 LASPSEVVQQVAEK 14 0 P31629 P31629 HIVEP2 Transcription factor HIVEP2 1 LAS(0.56)PS(0.44)EVVQQVAEK;LAS(0.677)PS(0.323)EVVQQVAEK 133.23 0.00019018 1625100.0 12649.0 10849.9 15443.4 20743.0 17712.2 15572.4 14250.6 18667.4 13453.5 16382.0 True False 16671.118884455638 14356.917993641391 15238.610425461691 15961.021826155324 15253.166764826834 14598.655366268638 15518.87579292977 15782.782264177427 14164.6245441354 15808.471166292717 1.0545686998501338 0.9081787759624492 0.9639521915284194 1.009649931246222 0.9648729851467283 0.9234704110664614 0.9816810006282941 0.9983749913672826 0.8960148261735534 1.0 13.94841023127749 -6.506947252295935 24.23087087354 0.9592790611456522 0.9784814171842704 0.05439697721265557 0.04570280841946495 1952.111616683287 2969057.2714070813 0.014062872435944505 0.015483234234327863 3.1120942969175724e-07 6.506947252295935 0.019202356038618196 LAS(ph)PSGSTSSGLEVVAPEGTSAPGGGPGTLDDSATICR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LASPSGSTSSGLEVVAPEGTSAPGGGPGTLDDSATICR 38 0 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 LAS(0.546)PS(0.173)GS(0.261)T(0.018)S(0.001)S(0.001)GLEVVAPEGTSAPGGGPGTLDDSATICR 144.44 1.4491e-29 18967000.0 13284.0 19821.0 14821.0 15930.0 16297.0 12832.0 14466.0 19283.0 14132.0 6708.5 True False 15532.718829040483 21788.697887574508 15174.38884895551 15037.493745756827 13103.719838993376 12159.067330555028 13095.675755229611 18776.841682027338 14338.653764882667 7924.697945543221 1.9600392261986395 2.749467303019199 1.914822363354486 1.897547874895822 1.6535292485643305 1.5343256505307157 1.6525141835335821 2.3694078703135006 1.8093628127424841 1.0 12.952140231804147 -5.457907500459386 6.081844614268111 1.7588731613491433 2.3573825215263837 0.3216358246584702 0.3682119593804461 0.26355441315649447 18.86182393366344 0.09479249572399465 0.1979595506266318 3.484115146276585e-06 5.457907500459386 0.5985093601772404 LAS(ph)PSGSTSSGLEVVAPEGTSAPGGGPGTLDDSATICR ddPTM_PC-9_Lapatinib_30min_R1 1 LASPSGSTSSGLEVVAPEGTSAPGGGPGTLDDSATICR 38 0 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 LAS(0.303)PS(0.303)GS(0.303)T(0.04)S(0.04)S(0.011)GLEVVAPEGTSAPGGGPGTLDDSATICR 89.98700000000001 2.4252e-14 33749000.0 19094.0 26440.0 16220.0 17289.0 20617.0 20028.0 16164.0 14311.0 30295.0 18848.0 True False 18821.716058589245 26378.779804468762 14886.454211010629 18560.49073441328 19404.34859458156 19171.4491275483 17000.89282894059 14975.941304874057 26882.858079507198 22105.851686618647 0.8514359150424685 1.1932939828975986 0.6734169043584898 0.8396188935642103 0.8777923994816091 0.8672567517112842 0.7690675333369649 0.6774650222565031 1.2160969168077889 1.0 14.432140698568453 -8.270126879814699 24.98594197718508 1.1080484588715709 0.8489496211075974 0.34727391308453714 0.14483859030339186 814.913917744896 2343728.341922595 0.13238885025762037 0.036309048396623925 5.368749246041245e-09 8.270126879814699 -0.25909883776397347 LAS(ph)PVAPGALTTPGGSAPAQVVHTQPPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LASPVAPGALTTPGGSAPAQVVHTQPPPR 29 0 Q96L91-5;Q96L91-2;Q96L91;Q96L91-4;Q96L91-3 Q96L91-5 EP400 E1A-binding protein p400 1 LAS(1)PVAPGALTTPGGSAPAQVVHTQPPPR;LAS(0.997)PVAPGALTT(0.003)PGGSAPAQVVHTQPPPR 98.552 5.7958e-11 6447800.0 23702.0 20909.8 27845.0 28649.0 33144.0 26825.0 26422.0 35370.0 23823.7 18142.2 True False 27714.280464161213 22985.586755945973 28508.93040275054 27043.88941131119 26649.671126194793 25418.249777286386 23919.116881285543 34441.574977612785 24172.076542487626 21431.23724642381 1.2931722114543733 1.0725272876992453 1.3302512624420584 1.2618911871653118 1.2434966222326604 1.1860374408168097 1.1160866078917997 1.6070735712358364 1.127889923691698 1.0 14.387427520173102 LAS(ph)SVLR ddPTM_PC-9_AZD4547_30min_R2 3 LASSVLR 7 0 J3QR09;J3KTE4;P84098 J3QR09 RPL19 Ribosomal protein L19;60S ribosomal protein L19 1 LAS(0.5)S(0.5)VLR;LAS(0.5)S(0.5)VLR;LAS(0.505)S(0.495)VLR 95.90899999999999 0.012975 9797800.0 57649.0 52637.0 60500.0 94120.0 77297.0 67884.0 54680.0 74314.0 57321.0 64142.0 True False 75980.18282630907 69650.88087736303 59697.73047000224 72422.08813950437 66565.64579334117 63639.20274869518 59546.414070804065 62830.478865834564 60350.87103685918 61896.40810330534 1.2275378354669282 1.1252814664320334 0.964478106231407 1.170053163967635 1.0754363271329552 1.0281566362054662 0.9620334344994765 1.0150908718478504 0.9750302624367694 1.0 15.91756807070298 -6.7805533556564646 2.4876369428472196 0.9897452588329222 1.111852200193235 0.46772838935806993 0.06399008801368021 0.2864667001891529 3.6339344421612 0.02516176594486474 0.023013431322232054 1.6574736938523998e-07 6.7805533556564646 0.12210694136031275 LAS(ph)SVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LASSVLR 7 0 J3QR09;J3KTE4;P84098 J3QR09 RPL19 Ribosomal protein L19;60S ribosomal protein L19 1 LAS(0.5)S(0.5)VLR;LAS(0.5)S(0.5)VLR;LAS(0.5)S(0.5)VLR 87.696 0.017768 7642300.0 68446.0 71884.0 76493.0 70419.0 85526.0 74616.0 72485.0 79046.0 64528.0 48817.0 True False 80032.55592987838 79020.16845519442 78316.88322131798 66473.65173147834 68767.79425352818 70703.0056060392 65618.69605404526 76971.12625616007 65471.59992501761 57667.13566484061 1.3878365035333957 1.3702807941503614 1.3580851956388642 1.1527129094432729 1.1924954041970146 1.226053709637368 1.1378872090235042 1.3347485594483761 1.135336429843443 1.0 15.815461744847973 -1.5228787452803376 0.09073677659473542 0.8914257026952495 2.2596525506070977 0.6367251857006897 0.07374640314798037 111.78405161818905 0.7313952780557379 1.4288667556124508 19.03177403610477 0.029999999999999995 1.5228787452803376 1.3682268479118482 LAS(ph)SVLR ddPTM_PC-9_Lapatinib_30min_R1 2 LASSVLR 7 0 J3QR09;J3KTE4;P84098 J3QR09 RPL19 Ribosomal protein L19;60S ribosomal protein L19 1 LAS(0.5)S(0.5)VLR;LAS(0.5)S(0.5)VLR 105.14 0.010247 5093600.0 24415.0 23363.0 26490.0 25073.0 22083.4 22524.4 21879.0 21713.9 25537.0 17196.4 True False 24066.83762283735 23308.904408918446 24312.09445435708 26916.952061076074 20784.49782963488 21561.083918940934 23011.78756523083 22722.807064489203 22660.7541434684 20168.77482723732 1.1932721659590255 1.1556926292538343 1.2054323905448303 1.3345853821881903 1.0305285277698695 1.0690329037648505 1.1409611026126438 1.1266329888220448 1.123556306100742 1.0 14.299835828182838 -6.278890927339688 24.99936956444638 1.0904381249475983 1.2162909207655463 0.5684394682579444 0.05958134741054053 691.8823809791165 991119.9449814765 0.019163524934024703 0.021781423629795457 5.261493917349967e-07 6.278890927339688 0.12585279581794806 LAS(ph)TSDIEEK ddPTM_PC-9_AZD4547_30min_R2 1 LASTSDIEEK 10 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 LAS(0.486)T(0.486)S(0.028)DIEEK 100.09 0.0041234999999999996 13031000.0 116630.0 135650.0 151700.0 159100.0 147020.0 151490.0 122590.0 152110.0 141720.0 124630.0 True False 153715.91394529692 179496.2097196708 149688.35888098084 122421.95307049665 126608.81074992596 142017.3063520099 133500.27251170183 128604.89464006943 149211.02987288582 120266.74163441945 1.2781248735627553 1.49248418374295 1.2446363545459282 1.0179202613024014 1.052733357778868 1.1808526981108933 1.1100348333831889 1.0693304972957183 1.2406674351122748 1.0 16.87587821160694 -5.52692935114119 5.335967710293751 1.1021432806704987 1.3837248263312494 0.6613702722233601 0.08349304989875318 0.09093275501828883 8.313819130688266 0.021724714210861053 0.041239875751913575 2.972149486858847e-06 5.52692935114119 0.28158154566075067 LAS(ph)TSDIEEKENR ddPTM_PC-9_AZD4547_30min_R2 2 LASTSDIEEKENR 13 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 LAS(0.909)T(0.09)S(0.001)DIEEKENR;LAS(0.917)T(0.041)S(0.041)DIEEKENR 180.3 0.00047573 35870000.0 99830.0 84133.0 119729.0 195338.0 167808.0 138689.0 122991.0 135465.0 132806.0 149432.0 True False 131573.863407005 111327.34693951385 118141.31523046111 150305.84204201563 144510.75577692586 130016.75490562993 133936.9607348622 114531.99692602041 139825.85403117732 144200.43116356098 0.9124373786217452 0.7720319976938179 0.8192854506548457 1.0423397546677897 1.0021520366538494 0.9016391550047236 0.9288249671247008 0.7942555788623904 0.9696632173906489 1.0 17.137715952722907 -5.7181897084603355 24.997971422662417 0.9393124385847156 0.8283294070194741 0.3374015882423568 0.07215519347192317 171.50030165947652 99124.51201310294 0.0204530289096424 0.03542542252177133 1.913419922595973e-06 5.7181897084603355 -0.11098303156524147 LAS(ph)TSDIEEKENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LASTSDIEEKENR 13 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 LAS(0.962)T(0.03)S(0.008)DIEEKENR;LAS(0.917)T(0.06)S(0.022)DIEEKENR 93.23700000000001 0.0019917000000000003 18283200.0 16506.7 21495.5 31765.0 37890.0 85774.0 91607.0 111402.0 132486.0 127424.0 111308.0 True False 19300.9582878141 23629.431181189517 32522.398069433344 35767.14614103742 68967.20043381103 86802.96765509318 100849.19607936445 129008.38288052053 129287.33493747584 131487.2592863569 0.14678957027904807 0.17970890342864806 0.2473425809158064 0.272019862115634 0.5245162216333994 0.6601625748853056 0.766988350253252 0.9811474022708331 0.9832689162370478 1.0 17.004563487985635 -6.7931333256677 0.7286345701819623 1.0266709489797288 0.13560885893603708 0.9890018948851625 0.03474545943687603 0.06403439223051922 0.07427555370539915 0.025662633119597406 0.02482538975244943 1.6101512530134433e-07 6.7931333256677 -0.8910620900436916 down LAS(ph)TSDIEEKENR ddPTM_PC-9_Lapatinib_30min_R1 3 LASTSDIEEKENR 13 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 LAS(0.754)T(0.092)S(0.155)DIEEKENR;LAS(0.492)T(0.492)S(0.016)DIEEKENR;LAS(0.705)T(0.218)S(0.077)DIEEKENR 173.06 1.207e-18 31708600.0 47093.9 40609.6 58095.8 46337.3 163832.0 279865.0 285939.0 263104.0 346890.0 296299.0 True False 46422.33235003647 40515.5709662464 53319.387580273185 49745.099618701446 154195.72386610476 267895.8263471791 300743.52230972785 275328.7723483744 307819.59528635873 347513.88735639956 0.13358410710771726 0.1165869118913653 0.15343095490624367 0.14314564519168238 0.44371096947836897 0.7708924336380071 0.8654143999756031 0.7922813515248261 0.885776386169766 1.0 18.406711106430883 -6.599834643930949 1.7913372566704748 0.8730759987713169 0.12560352046741716 0.9793842765775274 0.050022541018137356 0.0437969413896091 0.28734547570899827 0.01907050575228819 0.019640281859759495 2.512843005369382e-07 6.599834643930949 -0.7474724783038997 down LAS(ph)VSADAEVAR ddPTM_PC-9_AZD4547_30min_R2 2 LASVSADAEVAR 12 0 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 LAS(0.955)VS(0.045)ADAEVAR;LAS(0.999)VS(0.001)ADAEVAR 176.99 0.00016585 19736300.0 50494.0 53255.0 62913.0 103510.0 77749.0 66613.0 60713.0 70991.0 59202.0 59707.0 True False 66550.04165955438 70468.63729171455 62078.732513376024 79647.36871355829 66954.89339542908 62447.67857961861 66116.33938333452 60020.97216089111 62331.296856721594 57616.67610339637 1.1550482631126895 1.2230597468908935 1.0774438359125793 1.3823666011317035 1.162074904759774 1.0838472956605953 1.1475208889989597 1.0417291697490514 1.0818273644398468 1.0 15.814198813607353 -7.351507530723988 0.9576873482028645 1.0337218722721864 1.202464220039115 0.40882434005643176 0.07912930951771072 0.5948429729196517 1.0394645593288554 0.06165404341606426 0.032945294371879964 4.451357441402757e-08 7.351507530723988 0.16874234776692854 LAS(ph)VSADAEVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LASVSADAEVAR 12 0 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 LAS(0.999)VS(0.001)ADAEVAR;LAS(0.975)VS(0.025)ADAEVAR;LAS(0.998)VS(0.002)ADAEVAR 147.73 9.581100000000001e-05 24360400.0 56147.2 69576.0 62157.0 65233.0 96099.0 105621.0 113184.0 107126.0 92513.0 79066.0 True False 65651.81200225107 76483.0454682349 63639.05861173516 61578.20649823948 77269.09080244349 100082.04882485607 102462.3921388021 104314.05600937952 93865.82760759916 93400.0399138882 0.7029098923595739 0.8188759398684388 0.6813600794004832 0.6592952910406953 0.8272918392078106 1.0715418207222231 1.0970272842845579 1.1168523707864972 1.0049870181441078 1.0 16.511135546010685 -6.650433605245696 3.44518054789373 1.0693782904735678 0.7219043529904557 0.903472103480266 0.05315498736935598 0.06835874199535374 1.5847629904421867 0.018909577566865145 0.018712954048042504 2.236487085775452e-07 6.650433605245696 -0.34747393748311206 LAS(ph)VSADAEVAR ddPTM_PC-9_Lapatinib_30min_R1 3 LASVSADAEVAR 12 0 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 LAS(0.996)VS(0.004)ADAEVAR;LAS(0.977)VS(0.023)ADAEVAR;LAS(0.875)VS(0.125)ADAEVAR 172.58 0.00012601 26102100.0 29918.4 28311.8 33691.1 21473.7 59176.0 82787.0 94557.0 81565.0 97671.0 68667.0 True False 29491.758129637412 28246.245766571814 30921.14780940691 23052.94753216327 55695.38402449232 79246.39299592272 99452.69878904561 85354.80766767204 86670.26345877364 80535.99945697373 0.3661934827715567 0.35072819555262785 0.3839419392308715 0.28624401121984316 0.6915588606340884 0.9839872048556375 1.2348850136537772 1.0598342138073638 1.0761679751063018 1.0 16.297346189219127 -6.5956863315047265 2.242747790423136 1.098111427090763 0.3484128519370647 0.9630409444686352 0.06697037607874896 0.050788896251149164 0.5191271856402389 0.024453190885249106 0.025091371600839737 2.5369602844734784e-07 6.5956863315047265 -0.7496985751536983 down LAS(ph)YLDR ddPTM_PC-9_AZD4547_30min_R2 3 LASYLDR 7 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 LAS(0.993)Y(0.007)LDR;LAS(1)YLDR;LAS(0.999)Y(0.001)LDR 107.57 0.0098873 14107700.0 48570.5 49654.6 65784.0 94496.0 81706.0 76918.0 59558.0 84362.0 62518.0 72937.0 True False 64014.908670839795 65704.47840137387 64911.66117749794 72711.4071486464 70362.53224822125 72108.30530057369 64858.54662086592 71325.79134590442 65822.57384697336 70383.49783029503 0.9095158757978917 0.9335210727917648 0.9222568240926233 1.0330746466162324 0.9997021236124932 1.0245058504258686 0.9215021790654596 1.0133879892966018 0.9351989582228674 1.0 16.102949592657005 -5.734278210099558 24.872069766572746 0.9892172210827447 0.9229401671624774 0.45079367784173696 0.03431490108129107 192.1872684812138 175988.55798086803 0.009137301563411991 0.015820785140693537 1.8438338763123397e-06 5.734278210099558 -0.06627705392026728 LAS(ph)YLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LASYLDR 7 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 LAS(1)YLDR;LAS(1)YLDR;LAS(0.999)Y(0.001)LDR;LAS(0.999)Y(0.001)LDR 95.35799999999999 0.013152 8613400.0 32971.2 40390.7 37387.4 39364.6 49737.6 39753.0 46034.6 37793.6 38846.4 30727.999999999996 True False 38552.57294911619 44400.42176316307 38278.85740850408 37159.12908375512 39991.87432434908 37668.28269884307 41673.86942635789 36801.55804562922 39414.45510983145 36298.74315728581 1.0620911248101437 1.2231944662869436 1.0545504907053738 1.0237029123223682 1.1017426733223405 1.0377296683695882 1.1480802309264857 1.013852129429514 1.085835257133972 1.0 15.147631975369862 LAS(ph)YLDR ddPTM_PC-9_Lapatinib_30min_R1 4 LASYLDR 7 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 LAS(0.978)Y(0.022)LDR;LAS(1)YLDR;LAS(1)YLDR;LAS(1)YLDR 88.819 0.017015 19204900.0 71575.0 77197.0 80457.0 53057.7 81550.0 78347.0 71993.0 73042.0 85289.0 63290.8 True False 70554.32737475267 77018.25508946956 73842.13603300138 56959.74025329865 76753.38933346876 74996.28144577723 75720.44527554564 76435.7979729308 75682.85468701406 74230.53045030998 0.9504758614379273 1.03755496050275 0.9947677267702056 0.7673357566995642 1.03398680930682 1.0103158497025675 1.0200714559925315 1.029708362707943 1.0195650526527797 1.0 16.179725057906282 LASADGGS(ph)PEEEEDGEREPLLPR ddPTM_PC-9_AZD4547_30min_R2 1 LASADGGSPEEEEDGEREPLLPR 23 1 Q8TCG2 Q8TCG2 PI4K2B Phosphatidylinositol 4-kinase type 2-beta 1 LAS(0.011)ADGGS(0.989)PEEEEDGEREPLLPR 97.152 3.8724e-06 2601900.0 6002.7 6489.9 4507.0 7390.0 7722.4 6641.9 7216.0 6639.3 7592.5 5159.3 True False 7911.433736083638 8587.633258088397 4447.234235178512 5686.349674361846 6650.278058326955 6226.580943028673 7858.210020755702 5613.34874093624 7993.824049604046 4978.674477368702 1.5890642724376185 1.7248834598696396 0.8932566801453017 1.1421412868445178 1.3357527367086908 1.250650343044622 1.5783739339610077 1.1274785621057457 1.6056129168398436 1.0 12.281545974852445 -5.2279722374017386 24.991362931716836 1.2583640927657584 1.6569740353825568 0.368582427478075 0.21655352347597315 688.4295097025998 514078.083394148 0.054093738178749184 0.1430987508896898 5.91599451402327e-06 5.2279722374017386 0.3986099426167984 LASADGGS(ph)PEEEEDGEREPLLPR ddPTM_PC-9_Lapatinib_30min_R1 1 LASADGGSPEEEEDGEREPLLPR 23 1 Q8TCG2 Q8TCG2 PI4K2B Phosphatidylinositol 4-kinase type 2-beta 1 LAS(0.009)ADGGS(0.991)PEEEEDGEREPLLPR 99.13 3.1224e-06 1850100.0 5019.7 8807.4 6118.1 4845.6 7377.7 7570.2 5670.0 4491.3 5942.0 4743.0 True False 4948.118157499762 8787.00700642504 5615.093434548962 5201.9615884477425 6943.758191116279 7246.440192998114 5963.56485647693 4699.982194296758 5272.74938796606 5562.821230349757 0.8894979638216154 1.5795954323472958 1.009396707540055 0.935130102701624 1.2482439941144212 1.302655593795255 1.0720396377184993 0.8448918273077871 0.9478552643753646 1.0 12.44160102781752 -7.560595629995515 5.869109324337134 0.9258854240751642 1.1684710713404036 0.22433946423723783 0.19070211905615278 0.26832408445494366 24.426603217325567 0.08998022843193686 0.051921618014139116 2.7504538988031026e-08 7.560595629995515 0.24258564726523946 LASDDRPS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 2 LASDDRPSPPR 11 1 P98175-5;P98175-2;P98175;P98175-4;P98175-3 P98175-5 RBM10 RNA-binding protein 10 1 LAS(0.002)DDRPS(0.998)PPR;LAS(0.019)DDRPS(0.981)PPR 109.95 0.0083458 152050000.0 89853.0 88771.0 119056.0 161846.0 124535.0 118753.0 99417.0 126730.0 100310.0 115997.0 True False 118424.38494149705 117464.4897384807 117477.23965019155 124534.90519577362 107245.4648805744 111327.35613717223 108264.92040375117 107146.79046568919 105612.18181307624 111935.98033673901 1.057965317186117 1.0493899225710104 1.0495038261762006 1.1125547372804798 0.9580964454677213 0.9945627474049377 0.967203932802088 0.9572149200226556 0.9435052205319614 1.0 16.772314320490302 -6.275522518899931 24.9990078044014 0.9690365651723493 1.0647953687975917 0.8098114016892285 0.023073219061408003 333.4848848917179 591968.6724990021 0.007189452467135203 0.00818986157317531 5.302460977636656e-07 6.275522518899931 0.09575880362524247 LASDDRPS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 3 LASDDRPSPPR 11 1 P98175-5;P98175-2;P98175;P98175-4;P98175-3 P98175-5 RBM10 RNA-binding protein 10 1 LAS(0.002)DDRPS(0.998)PPR;LASDDRPS(1)PPR;LAS(0.001)DDRPS(0.999)PPR 103.11 0.0064396 144120500.0 145808.0 147374.0 164828.0 139070.0 143555.0 140981.0 138365.0 143469.0 160909.0 133545.0 True False 143728.75118208784 147032.76455763122 151276.4780944797 149297.6717239202 135111.37713998917 134951.57127276264 145528.8626748556 150135.09349933473 142785.73397311196 156628.07531247276 0.9176436018596871 0.9387382451345399 0.9658324524047389 0.9531986613898663 0.8626255342181929 0.8616052454423286 0.929136506239547 0.9585452237717629 0.9116228600029378 1.0 17.256983310844262 -11.306070609627817 2.9771920287223255 1.0175214223507745 0.9225449076130771 0.31516146447646187 0.03444190461649514 30621551.086356748 21735189.061387718 3843034.5462106 0.00960175326830524 4.942303261766296e-12 11.306070609627817 -0.09497651473769742 LASELAKT(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 1 LASELAKTPQK 11 1 Q13416 Q13416 ORC2 Origin recognition complex subunit 2 1 LASELAKT(1)PQK 117.93 0.011470999999999999 4288200.0 27956.0 14148.0 17718.0 18866.0 12980.0 15882.0 10740.0 12142.0 16350.0 11968.0 True False 27557.34231349748 14115.241175250525 16261.29443345786 20253.468575131083 12216.541919661857 15202.763882750265 11296.064648776399 12706.161646550263 14508.490826867217 14036.652853642412 1.9632417073238757 1.0055987935605117 1.1584880386379413 1.4428987299401261 0.8703315560370043 1.083076146519165 0.8047548633252086 0.9052130717369066 1.033614707020582 1.0 13.77691133462563 -3.044358864177966 1.5712683184387084 1.023335131355299 199.9975552154212 0.7091778613132413 0.1756188740047677 170.6494679027117 2.5903684099299795 0.05157676475413454 120587.97714938794 0.0009029030827499812 3.044358864177966 198.97422008406588 LASLGDTAS(ph)PLVK ddPTM_PC-9_AZD4547_30min_R2 2 LASLGDTASPLVK 13 0 Q6P4F7-3;Q6P4F7 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 1 LASLGDT(0.042)AS(0.958)PLVK;LASLGDT(0.013)AS(0.987)PLVK 137.95 6.1915e-05 11102500.0 68427.0 67904.0 69986.0 89899.0 90263.0 91728.0 72592.0 79877.0 70759.0 79871.0 True False 90185.3626299823 89852.64006490621 69057.93991195991 69174.17447570438 77731.54050279263 85992.23365936462 79052.54737066204 67533.84504085721 74499.17628263848 77074.7406008402 1.1701027071507155 1.165785825089455 0.8959866666253444 0.8974947425895106 1.0085215973071373 1.1156992938154269 1.0256608942748784 0.8762124207541091 0.9665835486681658 1.0 16.233970508422786 -5.245466536137149 24.08146578826968 0.9743595187245837 1.16794434981792 0.5675993226442289 0.06796056532916704 402.23808455160537 606430.0217446387 0.019327158293121437 0.05073234476301902 5.682421748599685e-06 5.245466536137149 0.19358483109333635 LASLGDTAS(ph)PLVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LASLGDTASPLVK 13 0 Q6P4F7-3;Q6P4F7 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 1 LASLGDT(0.028)AS(0.972)PLVK;LASLGDT(0.257)AS(0.743)PLVK;LASLGDT(0.047)AS(0.952)PLVK;LASLGDT(0.13)AS(0.87)PLVK 128.95 9.866299999999999e-05 7732600.0 81153.0 82731.0 82195.0 89008.0 97069.0 77337.0 83957.0 66694.0 61111.0 57927.0 True False 94890.6000551883 90943.98692986844 84154.84052627343 84021.17032782944 78049.02626564694 73281.31157599238 76003.98516395777 64943.35316813413 62004.63276434647 68428.70655012039 1.3867074922084928 1.3290326752451005 1.2298177880161227 1.2278643651738237 1.1405889457881273 1.0709147559630945 1.1107032266975394 0.9490659175410041 0.906120192684504 1.0 16.062314057136014 -6.152330665519747 0.4699649180995297 0.937694684630972 1.4391681739575206 0.914266260557144 0.044263717575574686 0.4265621581503275 0.16988423526198612 0.03945408418652195 0.10400652351799926 7.041567300911562e-07 6.152330665519747 0.5014734893265486 LASPMKPVPGT(ph)PPSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LASPMKPVPGTPPSSK 16 1 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 LAS(0.004)PMKPVPGT(0.989)PPS(0.004)S(0.004)K;LASPMKPVPGT(0.957)PPS(0.018)S(0.025)K 70.094 0.013165000000000001 44746000.0 136381.0 130314.0 117794.0 146340.0 160486.0 135993.0 152130.0 141187.0 123281.0 109045.0 True False 159467.6096524667 143250.71270477667 120602.65569623258 138141.04424068134 129039.9203583903 128861.28767800581 137719.14507417922 137480.99084999177 125083.75140026188 128813.9953002547 1.2379680428416258 1.1120741373704868 0.9362542898783461 1.0724071085497042 1.0017538859625383 1.0003671369530995 1.0691318497898257 1.0672830272016254 0.9710416256300574 1.0 16.974929821409425 -4.923728271071514 3.504126451827931 1.020000364527047 1.237423550054312 0.7221332623061516 0.04305563897523691 0.12773745944239254 2.8789575586490277 0.010693599738228206 0.05983552249786815 1.191987576330855e-05 4.923728271071514 0.21742318552726503 LASPQPS(ph)YAADANDSKAEYSDVLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LASPQPSYAADANDSKAEYSDVLAK 25 1 Q5TGY3 Q5TGY3 AHDC1 AT-hook DNA-binding motif-containing protein 1 1 LAS(0.134)PQPS(0.439)Y(0.385)AADANDS(0.037)KAEY(0.004)S(0.001)DVLAK 57.802 0.0022558000000000005 4172600.0 15656.0 10517.0 13792.0 22955.0 25869.0 28317.0 20042.0 19583.0 21084.0 17052.0 True False 18306.251579904987 11561.058255568389 14120.85358645128 21668.905771114118 20800.15515217031 26832.006670770497 18143.476668485535 19068.966999903612 21392.31361299081 20143.392616442266 0.9087968411518875 0.5739379892804922 0.7010166487508652 1.0757326823599036 1.0326043655224173 1.3320500266111368 0.9007160319992831 0.9466611391140913 1.0620015218056713 1.0 14.298019066802734 -5.760246013318208 24.99999997316137 1.0525553933277183 0.7125191670038898 0.5549893092188176 0.13192216072781995 22.516774948318837 471683.22506428347 0.036976263045593157 0.05972842697087745 1.7368167013878098e-06 5.760246013318208 -0.34003622632382846 LASPS(ph)GSTSSGLEVVAPEGTSAPGGGPGTLDDSATICR ddPTM_PC-9_AZD4547_30min_R2 1 LASPSGSTSSGLEVVAPEGTSAPGGGPGTLDDSATICR 38 0 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 LAS(0.171)PS(0.35)GS(0.35)T(0.096)S(0.027)S(0.007)GLEVVAPEGTSAPGGGPGTLDDSATICR 98.39399999999999 4.5462999999999995e-20 30500000.0 11787.0 11557.0 21425.0 13819.0 16641.0 13142.0 13741.0 11443.0 14249.0 13357.0 True False 15535.02081516947 15292.574240547248 21140.8905011537 10633.243051421701 14330.684394568905 12320.228662473515 14963.922380155786 9674.747283980758 15002.173050089967 12889.375495554392 1.205257835845311 1.1864480358898484 1.6401795811166564 0.8249618497877697 1.1118214687369166 0.9558437231286203 1.160950147298984 0.7505986063729484 1.1639177596512948 1.0 13.653894744777887 -5.777236194802073 24.997277583519743 0.9951456218415536 1.3282105750039244 0.46513507110459273 0.17101504123705402 201.68269798749552 319147.21687026776 0.045996468172514036 0.06847772931646698 1.670182024352747e-06 5.777236194802073 0.3330649531623707 LASPS(ph)GSTSSGLEVVAPEGTSAPGGGPGTLDDSATICR ddPTM_PC-9_Lapatinib_30min_R1 1 LASPSGSTSSGLEVVAPEGTSAPGGGPGTLDDSATICR 38 0 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 LAS(0.375)PS(0.469)GS(0.141)T(0.011)S(0.003)S(0.001)GLEVVAPEGTSAPGGGPGTLDDSATICR 132.9 2.3041999999999998e-30 32304000.0 11705.0 30228.0 24524.0 23398.0 11316.0 22328.0 21239.0 23246.0 27367.0 13942.0 True False 11538.084553565895 30158.008923202797 22507.731385377592 25118.766973439888 10650.415128111983 21373.08348911017 22338.651496774866 24326.094023695234 24284.640272714078 16351.856123452733 0.7056131405790281 1.8443171647008634 1.3764633944580618 1.536141633328902 0.6513275953325305 1.307073847014573 1.3661232907214453 1.48766561056059 1.485130500743809 1.0 13.997166787022845 -4.722637091840435 24.242511344608396 1.3402350796612381 0.7056040317986932 0.2801816204707006 0.30473668642533663 7495.455735459058 4682488.200977349 0.07669031520545619 23.453317708639762 1.8939255727811434e-05 4.722637091840435 -0.6346310478625449 LASPSGS(ph)TSSGLEVVAPEGTSAPGGGPGTLDDSATICR ddPTM_PC-9_AZD4547_30min_R2 1 LASPSGSTSSGLEVVAPEGTSAPGGGPGTLDDSATICR 38 0 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 LAS(0.083)PS(0.364)GS(0.434)T(0.04)S(0.04)S(0.038)GLEVVAPEGTSAPGGGPGTLDDSATICR 97.897 4.9658000000000006e-20 32219000.0 3292.0 10917.0 24935.0 14465.0 15073.0 15201.0 11399.0 16033.0 17321.0 7005.2 True False 4338.7875221462555 14445.706756429387 24604.345607760435 11130.317732022213 12980.374128918756 14250.479066980657 12413.488917210965 13555.46825168779 18236.552698477662 6759.950080216933 0.6418372133906379 2.136954649813895 3.639722973660015 1.6465088647023012 1.9201878674971227 2.1080746008294997 1.8363284891021865 2.0052615908152953 2.697734817871974 1.0 12.722796877428513 LASPSGS(ph)TSSGLEVVAPEGTSAPGGGPGTLDDSATICR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LASPSGSTSSGLEVVAPEGTSAPGGGPGTLDDSATICR 38 0 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 LAS(0.162)PS(0.162)GS(0.559)T(0.056)S(0.056)S(0.006)GLEVVAPEGTSAPGGGPGTLDDSATICR;LAS(0.049)PS(0.182)GS(0.635)T(0.063)S(0.055)S(0.016)GLEVVAPEGTSAPGGGPGTLDDSATICR;LAS(0.086)PS(0.39)GS(0.477)T(0.041)S(0.004)S(0.001)GLEVVAPEGTSAPGGGPGTLDDSATICR 109.17 3.3710000000000007e-26 78015000.0 16690.8 20437.7 20628.1 34134.0 36707.4 35249.7 39929.6 31957.2 27624.6 18796.4 True False 19516.22278167336 22466.619787946194 21119.952136504886 32221.582643921105 29514.848476275718 33401.14367844964 36147.179222730294 31118.35736145228 28028.55751439128 22204.03852777947 0.8789492396735223 1.0118258333878412 0.951176161493402 1.4511586531255873 1.3292558666455967 1.5042823690231608 1.6279551657914195 1.4014728592062253 1.2623180003639767 1.0 14.438534481084774 -5.757611148280396 24.9759034018994 1.399678978939287 0.953767825905897 0.5853962190229403 0.16070199577986485 61.9636076902729 404251.60903847805 0.04322931157708354 0.07137792667430297 1.747385999530202e-06 5.757611148280396 -0.4459111530333899 LASPSGS(ph)TSSGLEVVAPEGTSAPGGGPGTLDDSATICR ddPTM_PC-9_Lapatinib_30min_R1 2 LASPSGSTSSGLEVVAPEGTSAPGGGPGTLDDSATICR 38 0 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 LAS(0.049)PS(0.169)GS(0.608)T(0.058)S(0.058)S(0.058)GLEVVAPEGTSAPGGGPGTLDDSATICR;LAS(0.276)PS(0.132)GS(0.456)T(0.046)S(0.046)S(0.046)GLEVVAPEGTSAPGGGPGTLDDSATICR 98.552 4.4124000000000003e-20 50595000.0 16720.0 13355.800000000001 13158.0 7824.6 20170.6 13703.400000000001 21264.9 16648.6 19437.0 12898.099999999999 True False 16481.569733927525 13324.875465677915 12076.200031348819 8400.047186100428 18984.20496492538 13117.337526185607 22365.892472045194 17422.154734702406 17247.800379316104 15127.519399362054 1.0895090793684636 0.8808367792435183 0.7982934751257424 0.5552825261261717 1.2549450087451857 0.8671175478207472 1.4784904174697928 1.1516861604842576 1.1401605196449767 1.0 13.884887814318686 -6.28318763601453 24.893624960413707 1.1587246658654087 0.8322068077724705 0.3960905233190465 0.19197329974984575 776.0358230187915 888268.4908210611 0.05977566417769453 0.06783673771378015 5.209695786673859e-07 6.28318763601453 -0.3265178580929382 LASS(ph)VLR ddPTM_PC-9_AZD4547_30min_R2 1 LASSVLR 7 0 J3QR09;J3KTE4;P84098 J3QR09 RPL19 Ribosomal protein L19;60S ribosomal protein L19 1 LAS(0.39)S(0.61)VLR 80.455 0.025381 5403600.0 21830.0 21925.0 29204.0 35659.0 30246.0 26945.0 22429.0 27775.0 21980.0 27994.0 True False 28771.485907792452 29011.827483256762 28816.735878445375 27438.36847605807 26046.864983963176 25260.12489045416 24425.137549269653 23483.011956005023 23141.817926940646 27013.938580710445 1.0650607582389708 1.0739577050779603 1.0667358183386941 1.0157115147826201 0.9642009404197796 0.9350774532556089 0.9041679530104008 0.8692924167960198 0.8566621212156482 1.0 14.72141637691629 -6.344998980526633 1.1440194824844263 0.8971933842744569 1.0746902221419643 0.7761170912178478 0.03680552756224881 0.20348918595764331 0.5544416095893786 0.015582219372948486 0.021221456505295312 4.5185700507373624e-07 6.344998980526633 0.17749683786750736 LASS(ph)VLR ddPTM_PC-9_Lapatinib_30min_R1 2 LASSVLR 7 0 J3QR09;J3KTE4;P84098 J3QR09 RPL19 Ribosomal protein L19;60S ribosomal protein L19 1 LAS(0.227)S(0.773)VLR;LAS(0.13)S(0.87)VLR 118.74 0.006791800000000001 11287900.0 57921.0 47550.0 62045.0 54730.0 54205.0 47634.0 54233.0 48823.0 51115.0 46820.0 True False 57095.03591858945 47439.90089646332 56943.89960062605 58755.026773927915 51016.768471130265 45596.80486027743 57040.91937589299 51091.49481712433 45357.89043518768 54912.774616271534 1.03974050332673 0.8639137473560864 1.03698820535928 1.0699700968400505 0.9290510054833977 0.8303496805416634 1.038755003266414 0.9304118244643407 0.8259988819021978 1.0 15.744854188737369 -6.48152011034808 24.374799469290576 0.922506304296206 0.9957350796543429 0.17944896648556496 0.07994626641238008 715.7828125022675 421847.8726809102 0.025046916786758595 0.02839659016595067 3.299741278451482e-07 6.48152011034808 0.07322877535813699 LAST(ph)SDIEEK ddPTM_PC-9_AZD4547_30min_R2 1 LASTSDIEEK 10 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 LAS(0.26)T(0.703)S(0.036)DIEEK 119.03 0.0020145 14277000.0 128730.0 151230.0 172430.0 159220.0 151250.0 161370.0 132730.0 190640.0 149180.0 146380.0 True False 169663.46224966232 200112.1400361651 170143.4655362393 122514.28892447827 130251.54826504078 151279.5083901501 144542.71286791938 161180.96847138787 157065.35024299382 141255.2807546042 1.2011123502307164 1.416670151849473 1.2045104765450936 0.8673253719789512 0.9221003814457056 1.0709653301596596 1.0232729855885974 1.141061541985107 1.1119255110600479 1.0 17.107945277370447 -5.552980369545605 7.877636253527348 1.0240727808339098 1.30963207717252 0.6346874817563137 0.09078276545177472 0.12392032111496791 26.938931485723632 0.026102095599726913 0.04587993332884212 2.799107838665209e-06 5.552980369545605 0.2855592963386102 LAST(ph)SDIEEKENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LASTSDIEEKENR 13 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 LAS(0.143)T(0.429)S(0.429)DIEEKENR 79.804 0.009707200000000001 9170100.0 13153.0 12700.0 15880.0 19339.0 51580.0 66814.0 74598.0 96475.0 79683.0 71995.0 True False 15379.543116408431 13960.772068623994 16258.639425235377 18255.498527883945 41473.269270128105 63310.15622067513 67531.53739725011 93942.63347371192 80848.21312957446 85047.12358789361 0.1808355470189905 0.1641533714446669 0.19117212598533762 0.2146515691270551 0.48765046388978395 0.7444126685277723 0.7940484586460861 1.1045950704802505 0.9506284247934652 1.0 16.3759748223087 -6.76169365235964 1.0578890573677433 1.0161160139769334 0.1528639402324569 0.9716360933257915 0.06042272543341891 0.07260276379374817 0.17345944409826608 0.03259153353410113 0.02951868783884509 1.7310369874484758e-07 6.76169365235964 -0.8632520737444765 down LASTNS(ph)SVLGADLPSSMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LASTNSSVLGADLPSSMK 18 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;H0YA99;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 1 LAS(0.026)T(0.131)NS(0.422)S(0.422)VLGADLPSSMK 93.495 0.00090725 3550500.0 49357.0 100500.0 48278.0 84298.0 66050.0 53905.0 65402.0 59327.0 48007.0 54284.0 True False 57712.16525481413 110476.97581863891 49429.13061533458 79575.0563578035 53107.97664389231 51078.126905670935 59206.64909052443 57769.72911215248 48709.01155467887 64125.25948809243 0.8999911378998916 1.7228308579266434 0.7708215297672705 1.2409315298377854 0.8281912161892157 0.796536767467674 0.9232968344014054 0.9008888162531316 0.7595916483382615 1.0 15.968605138264099 -5.781238945466656 1.2799691959440105 0.8679913917155871 1.2666247800594386 0.22561585710382182 0.24655656913184898 0.6151152606804637 2.0043627104231736 0.08040596146099732 0.19836271776413705 1.6548592221998332e-06 5.781238945466656 0.3986333883438514 LASTNS(ph)SVLGADLPSSMK ddPTM_PC-9_Lapatinib_30min_R1 1 LASTNSSVLGADLPSSMK 18 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;H0YA99;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 1 LAST(0.001)NS(0.629)S(0.37)VLGADLPSSMK 117.3 0.00011144 2855900.0 13891.0 14247.0 18632.0 16266.0 16881.0 19149.0 13449.0 13229.0 18424.0 12569.0 True False 13692.911792702589 14214.01194683308 17100.148881599885 17462.255901785327 15888.092769322939 18330.04190849922 14145.323413537611 13843.66763483886 16348.895106679 14741.534902860247 0.9288660836834435 0.9642151947200007 1.1599978560090107 1.1845615817384925 1.0777773735243967 1.243428315252485 0.9595556708815339 0.9390926878416725 1.1090361495197412 1.0 13.847599126605102 -10.14485196714704 9.090821984469072 1.0000059147114189 1.0655359241023508 0.030107051061952217 0.1062742823387625 0.0 0.0 0.10966555786547101 0.02659780462186016 7.16387555202703e-11 10.14485196714704 0.0655300093909319 LASTNSS(ph)VLGADLPSSMK ddPTM_PC-9_AZD4547_30min_R2 1 LASTNSSVLGADLPSSMK 18 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;H0YA99;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 1 LAS(0.004)T(0.016)NS(0.311)S(0.669)VLGADLPSSMK 98.169 0.0058762 0.0 12132.0 13221.0 13244.0 14068.0 17563.0 16401.0 17025.0 14103.0 14117.0 10383.0 True False 15989.723638723683 17494.42969925372 13068.375906524132 10824.839948433351 15124.680609447367 15375.442877281084 18540.192018204805 11923.70540469986 14863.195799573305 10019.494330339236 1.5958613390604424 1.746039183462605 1.304294954981193 1.0803778705333973 1.5095253423767627 1.534552779846776 1.8504119476433778 1.1900506164861668 1.4834277369235334 1.0 13.290522079148369 -9.098681220221488 1.1007794979168202 1.0003287496482756 1.4855282811070933 0.291725200966526 0.22341927773134224 3.473310797614023 5.383164518751409 0.23107192052133227 0.07056076748685383 7.967439598963851e-10 9.098681220221488 0.4851995314588178 LASTNSS(ph)VLGADLPSSMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LASTNSSVLGADLPSSMK 18 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;H0YA99;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 1 LAS(0.023)T(0.128)NS(0.212)S(0.607)VLGADLPS(0.015)S(0.015)MK 96.096 0.006369 0.0 14437.0 15755.0 16508.0 19952.0 23337.0 28163.0 32057.0 27808.0 29354.0 25584.0 True False 16880.89895625245 17319.05227883235 16901.61332693863 18834.154125256766 18764.282376056235 26686.082701871983 29020.32888741848 27078.069465011482 29783.246717687947 30222.17667716744 0.5585599983936896 0.5730577404742897 0.5592454013978296 0.6231898624127158 0.6208779260506563 0.8829967141987181 0.9602329176158597 0.8959668839957745 0.9854765603362017 1.0 14.88331995031913 -6.785029295251605 2.6395427167268015 0.9520447947635367 0.5779731026226422 0.9709757161026888 0.031214162673278 0.04289436520491977 0.6122652914007909 0.011873604838485244 0.010851476924419711 1.6404791112610702e-07 6.785029295251605 -0.3740716921408944 LASVPAGGAVAVSAAPGS(ph)AAPAAGSAPAAAEEK ddPTM_PC-9_AZD4547_30min_R2 2 LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEK 33 0 P05387;H0YDD8 P05387 RPLP2 60S acidic ribosomal protein P2 1 LASVPAGGAVAVSAAPGS(0.988)AAPAAGS(0.012)APAAAEEK;LASVPAGGAVAVS(0.093)AAPGS(0.891)AAPAAGS(0.016)APAAAEEK 159.36 2.0182e-22 13301500.0 85212.0 80226.0 95378.0 90076.0 95115.0 97339.0 102282.0 109388.0 97298.0 102890.0 True False 112307.64348029373 106157.48559506316 94113.22540112196 69310.36986032712 81909.92405440919 91252.37694236106 111384.89985351101 92484.598086174 102440.97364219622 99287.85241727866 1.1311317623055899 1.069189059996115 0.9478825768694321 0.6980750230051841 0.8249742749008714 0.9190688963525289 1.1218381417435832 0.9314794895299727 1.031757371603385 1.0 16.599329598517706 -9.533704277453289 15.6341617358447 0.9999946183979039 0.9570205073916963 0.004542767974281325 0.12740176856027888 0.0 0.0 0.1358423169696171 0.03294660125260975 2.926144188244782e-10 9.533704277453289 -0.04297411100620763 LASVPAGGAVAVSAAPGS(ph)AAPAAGSAPAAAEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEK 33 0 P05387;H0YDD8 P05387 RPLP2 60S acidic ribosomal protein P2 1 LASVPAGGAVAVS(0.075)AAPGS(0.925)AAPAAGSAPAAAEEK;LASVPAGGAVAVSAAPGS(0.862)AAPAAGS(0.138)APAAAEEK 160.98 1.243e-23 14888900.0 96954.0 98232.0 106116.0 100057.0 106568.0 90008.0 102885.0 93818.0 96119.0 78665.0 True False 113366.39727121295 107983.82376732868 108646.20788717095 94451.13067917086 85686.76540478914 85287.82202997165 93138.98797710471 91355.37690838792 97524.55853571734 92926.34178820276 1.2199597561862174 1.1620367453336844 1.1691648008139268 1.016408575454777 0.9220933887625317 0.9178002748064614 1.0022883305724724 0.9830945149719186 1.049482382056907 1.0 16.50379999424488 -5.79500182676542 3.488703133185534 0.9756915502989479 1.18629842969519 0.8507263935499413 0.03854397057165642 0.08583550309789474 2.1665704572122224 0.011855372951674494 0.01968208184301002 1.6032386470006752e-06 5.79500182676542 0.210606879396242 LASVPAGGAVAVSAAPGS(ph)AAPAAGSAPAAAEEK ddPTM_PC-9_Lapatinib_30min_R1 2 LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEK 33 0 P05387;H0YDD8 P05387 RPLP2 60S acidic ribosomal protein P2 1 LASVPAGGAVAVSAAPGS(0.997)AAPAAGS(0.003)APAAAEEK;LASVPAGGAVAVSAAPGS(1)AAPAAGSAPAAAEEK 185.64 2.9743e-35 13128700.0 65963.0 94133.0 100754.0 86483.0 111615.0 101152.0 102256.0 101782.0 99627.0 83806.0 True False 65022.355523867314 93915.0408220141 92470.39504168698 92843.2483188309 105050.02514353312 96825.9647568287 107550.31533754931 106511.16329345874 88405.95814118054 98291.7554355245 0.6615240030637097 0.9554722103179717 0.9407746827997583 0.9445680149616659 1.0687572388758666 0.985087348657057 1.0941946744261584 1.0836225563529167 0.8994239420128309 1.0 16.58478279010197 -4.26134249224754 1.1678493686912477 1.0161544302171548 2.1531506362769266e-16 0.72747119678944 0.0619060527900988 2.3878216725821217 1.1895695158168962 0.018705607918857718 3.977485248303623 5.478447545342843e-05 4.26134249224754 -1.0161544302171546 LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKK ddPTM_PC-9_AZD4547_30min_R2 2 LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKK 34 1 P05387;H0YDD8 P05387 RPLP2 60S acidic ribosomal protein P2 0 ; 165.34 1.8275e-49 2366500.0 13161.1 2613.7 12223.099999999999 52969.0 31609.0 11976.400000000001 7609.4 11310.900000000001 6894.700000000001 19424.9 False True 17346.056032113942 3458.5274113107503 12061.013707568341 40757.81541289214 27220.63596105574 11227.513814735034 8286.621858638924 9563.06030362474 7259.139766190976 18744.8401634794 0.9253776442388284 0.1845055695939731 0.6434311310408948 2.1743485171082253 1.4521668749189842 0.5989655668875543 0.44207482093038925 0.5101702772721671 0.3872606916293674 1.0 14.194205903423585 -6.896895866399701 8.932683261082163 0.5409008947833367 1.0627441485392701 0.18436516740839248 0.5097635619827146 0.5201641801732171 40.891023085973686 0.20167736032552888 0.1778969678637668 1.267955855398005e-07 6.896895866399701 0.5218432537559334 LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKK ddPTM_PC-9_Lapatinib_30min_R1 1 LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKK 34 1 P05387;H0YDD8 P05387 RPLP2 60S acidic ribosomal protein P2 0 127.44 1.454e-17 0.0 20338.0 3301.7 6028.9 3955.8 3993.0 2567.2 924.99 1191.4 4110.7 2201.6 False True 20047.976390467593 3294.0551165058446 5533.227114227004 4246.722728161957 3758.1395905400445 2457.4068404354903 972.8814561891695 1246.756793419535 3647.7096784099754 2582.1436265524007 7.764082595682347 1.275705612434877 2.14288123144211 1.6446500823937713 1.455433985892488 0.9516925453587355 0.37677278916050505 0.4828378950725396 1.4126672276864343 1.0 11.33435353455273 -4.761218524461969 7.6693534626131745 1.1902139894669008 7.86187546316108 0.9398025384560849 0.498915687044081 0.02460065174651044 11.066362301060506 0.1432307133477478 0.850025619668069 1.7329318170169925e-05 4.761218524461969 6.671661473694179 LASVS(ph)ADAEVAR ddPTM_PC-9_AZD4547_30min_R2 2 LASVSADAEVAR 12 0 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 LAS(0.112)VS(0.888)ADAEVAR;LAS(0.256)VS(0.744)ADAEVAR 158.86 0.00021840000000000002 38204000.0 66176.0 57723.0 75938.0 118029.0 102949.0 69018.0 64795.0 75467.0 68670.0 72083.0 True False 87218.59145369112 76380.83091521225 74931.01250299231 90819.23757987218 88656.30837909212 64702.29354942912 70561.62947545266 63805.30920913885 72299.75600741645 69559.39611035761 1.253872177316157 1.098066331600008 1.0772234477727853 1.3056357970069972 1.2745410877121015 0.9301733075252323 1.0144083103238128 0.9172780785490178 1.0393959702110005 1.0 16.085957787289203 -6.7666740244645 24.99968942577889 0.9772158146146395 1.1949412337321441 0.6829100422501644 0.07541807688893494 83.42318526887985 398410.66605623177 0.027795317345286487 0.025233861176641545 1.7112993111592208e-07 6.7666740244645 0.21772541911750465 LASVS(ph)ADAEVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LASVSADAEVAR 12 0 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 LAS(0.103)VS(0.897)ADAEVAR 171.26 0.0010969 8183600.0 6969.5 9073.9 10960.0 9603.3 20288.0 19823.0 24815.0 25836.0 26310.0 17577.0 True False 8149.298696100393 9974.696824684037 11221.327966031462 9065.25823531868 16312.712038626592 18783.44698360291 22464.34355495803 25157.832375504757 26694.733976370157 20763.570960544566 0.3924805955384979 0.48039409230898644 0.5404334344682087 0.4365943725452959 0.7856409704103594 0.9046347094772698 1.081911372453482 1.2116332216317833 1.2856523585030786 1.0 14.341766962167902 -6.738155711196928 1.150256110901816 1.1852378329111437 0.4475121599754055 0.9263964740256 0.08588519573192283 0.11139403573280422 0.3126233892598593 0.04340361600792267 0.04005528505323342 1.8274448897208345e-07 6.738155711196928 -0.7377256729357382 down LASVS(ph)ADAEVAR ddPTM_PC-9_Lapatinib_30min_R1 1 LASVSADAEVAR 12 0 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 LAS(0.34)VS(0.66)ADAEVAR 120.59 0.00048587 5087900.0 5989.0 7444.1 7168.9 7836.5 14136.0 22295.0 23530.0 20096.0 22878.0 18878.0 True False 5903.59576175191 7426.863643814144 6579.500714754259 8412.82235179766 13304.548272445298 21341.494822183424 24748.268266825777 21029.733524054875 20301.23872397971 22141.037146646177 0.26663591785022406 0.33543431568376786 0.2971631668009234 0.3799651432802007 0.6008999571395692 0.9638886688474815 1.117755600286978 0.9498079690110797 0.9169054994813036 1.0 14.434435183027428 -6.5531690153714175 2.0707722141795903 1.0032891974430658 0.3112196909847359 0.9705419253773719 0.05524093029041869 0.05291253288516121 0.4587748952204451 0.02228520410459491 0.0235877537520589 2.797892245639769e-07 6.5531690153714175 -0.6920695064583299 down LASYLDR ddPTM_PC-9_AZD4547_30min_R2 1 LASYLDR 7 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 0 130.04 0.020263999999999997 69115000.0 104570.0 93910.0 170050.0 178800.0 147190.0 134870.0 112020.0 159190.0 110930.0 132780.0 False True 137821.08480888008 124264.57098985824 167795.02589130384 137580.4224324627 126755.20918433968 126436.55757934904 121989.56298850555 134590.84332228402 116793.53333191642 128131.41261508659 1.0756229249021219 0.969821283116229 1.3095541715080345 1.0737446784088882 0.9892594376144037 0.9867725251665727 0.9520660117512989 1.0504125458025027 0.9115136635757716 1.0 16.967264683671296 -6.1872376480736 4.3190313135133485 0.9826777963538554 1.1152171836077718 0.3494132727971251 0.08486059721477587 0.2650088049935608 9.435829389978831 0.0257916914227106 0.03350031349048839 6.497740335007858e-07 6.1872376480736 0.13253938725391634 LASYLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LASYLDR 7 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ; 120.62 0.027533 47976000.0 97566.0 91629.0 106257.0 115354.0 107065.0 99074.0 110095.0 106286.0 102177.0 87452.0 False True 114081.99678366169 100725.32156503506 108790.56986191655 108891.08936271376 86086.38182253348 93878.38503019085 99666.00458122541 103496.1051193256 103671.14532510751 103306.35533034884 1.1043076335318862 0.9750157310548779 1.0530869036472201 1.0540599270442392 0.8333115764973991 0.9087377512253761 0.9647615992502836 1.0018367678190754 1.0035311476587492 1.0 16.656569484898668 LASYLDR ddPTM_PC-9_Lapatinib_30min_R1 3 LASYLDR 7 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ;; 133.81 0.019278999999999998 187511000.0 332107.0 318541.0 337240.0 334328.0 334973.0 310108.0 305929.0 275460.0 316448.0 300130.0 False True 327371.0932790348 317803.43788560043 309513.42898404563 358915.596405514 315270.5467222567 296845.40373705595 321768.50669790636 288258.87721617066 280806.2938948308 352007.070601913 0.9300128338878193 0.9028325406707707 0.8792818520798303 1.0196260995320003 0.8956369716754871 0.843293866880192 0.9140967144429789 0.8189008156093672 0.7977291291753523 1.0 18.425244882333097 -6.519687486487018 24.7616466795353 0.8663327645028623 0.9307898384864676 0.15515540700015884 0.0624199746048009 196.25244183329002 1522784.0103372617 0.01995158243289061 0.02033749405140087 3.0221256263742917e-07 6.519687486487018 0.06445707398360523 LATATGAK ddPTM_PC-9_AZD4547_30min_R2 1 LATATGAK 8 0 Q9BZH6 Q9BZH6 WDR11 WD repeat-containing protein 11 0 94.662 0.030706999999999998 4679600.0 43936.0 33167.0 39473.0 34230.0 31737.0 41060.0 39325.0 34679.0 38180.0 41035.0 False True 57906.73407442824 43887.58413396476 38949.56222879997 26338.802348228168 27330.86537049656 38492.511709112936 42824.848817380545 29320.157394142156 40198.11685398514 39598.37714008192 1.4623511935749105 1.108317746929615 0.9836151135945113 0.6651485300787173 0.6902016533104827 0.9720729607918802 1.0814798966605315 0.7404383591383084 1.01514556295531 1.0 15.273153685108582 -4.848056145941726 1.7883571400824398 0.8756898238887681 1.6020014083276486 0.618103976365092 0.13831955590624578 0.5142524365307675 1.8909484308859519 0.04019695502119128 0.613222989948492 1.4188740766436681e-05 4.848056145941726 0.7263115844388804 LATATGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LATATGAK 8 0 Q9BZH6 Q9BZH6 WDR11 WD repeat-containing protein 11 0 ; 99.375 0.024045 18905400.0 105956.0 183635.0 124717.0 100975.0 138967.0 94767.0 114306.0 83650.0 98132.0 101659.0 False True 123892.25807360842 201865.06919856436 127690.72627185621 95317.69811536692 111737.41393295623 89797.25169223103 103478.1081762253 81454.2761345011 99566.99485249564 120088.97196779902 1.0316705692744979 1.6809625887437274 1.0633010190652272 0.7937256565151183 0.9304552458232201 0.7477560197310167 0.8616786910622584 0.6782827332083621 0.8291102273670375 1.0 16.8737441457312 -5.517642876192378 4.99394323782695 0.827091119449513 1.3647257516654687 0.6040042811799373 0.16848986430343185 0.10001125683211548 7.24735717421823 0.04221718235942305 0.08219972897367249 3.036387003077242e-06 5.517642876192378 0.5376346322159558 LATEEPPPRS(ph)PPESESEPYTFSHPNNGDVSSK ddPTM_PC-9_AZD4547_30min_R2 1 LATEEPPPRSPPESESEPYTFSHPNNGDVSSK 32 1 Q9H5V8-2;Q9H5V8 Q9H5V8-2 CDCP1 CUB domain-containing protein 1 1 LAT(0.197)EEPPPRS(0.504)PPES(0.036)ES(0.208)EPY(0.033)T(0.018)FS(0.004)HPNNGDVSSK 45.685 0.0069158 19005000.0 16456.0 30749.0 36469.0 30100.0 21130.0 22305.0 25900.0 33145.0 23998.0 20537.0 True False 21688.66569393644 40688.01292053191 35985.397231578696 23160.910040364233 18196.464230349193 20910.264823959184 28205.049825051658 28023.20184632895 25266.485287112 19818.00588097629 1.0943919294501692 2.053083098516444 1.8157930443507346 1.1686801477133917 0.9181783646464831 1.0551144726438586 1.4232032220823119 1.4140273251825501 1.2749257134576701 1.0 14.274524183125264 -5.7684042003568265 24.998565090924753 1.1905378982948964 1.69428875340642 0.38651205689952506 0.2727410220308536 156.33757274646467 561138.3202685288 0.07835298834376649 0.11911527908189282 1.7044952670576493e-06 5.7684042003568265 0.5037508551115235 LATEEPPPRS(ph)PPESESEPYTFSHPNNGDVSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LATEEPPPRSPPESESEPYTFSHPNNGDVSSK 32 1 Q9H5V8-2;Q9H5V8 Q9H5V8-2 CDCP1 CUB domain-containing protein 1 1 LAT(0.109)EEPPPRS(0.876)PPES(0.01)ES(0.004)EPYTFS(0.001)HPNNGDVSSK 61.43600000000001 0.00021245 10070000.0 5875.9 7695.0 7535.5 9279.5 18281.0 9888.9 12312.0 10458.0 9839.3 9876.3 True False 6870.573815684956 8458.908745516665 7715.174898542888 8759.599699544913 14698.969281256534 9370.308675586479 11145.718228839129 10183.488581166932 9983.181148373193 11666.795009252219 0.5888998486933494 0.7250413450144982 0.6612934308372141 0.7508145718338424 1.259897792804252 0.8031604796480493 0.955336767295572 0.8728608476527643 0.8556918280004187 1.0 13.510120671588178 -6.016049752390099 24.949022505291182 0.9492233548952697 0.6719043853014282 0.5656267754184086 0.12036356274649482 524.6844092016318 815612.6262721888 0.034512049711548684 0.045917107477838046 9.637186145514165e-07 6.016049752390099 -0.2773189695938415 LATGSDDNCAAFFEGPPFK ddPTM_PC-9_Lapatinib_30min_R1 1 LATGSDDNCAAFFEGPPFK 19 0 O75083;D6RD66 O75083 WDR1 WD repeat-containing protein 1 0 196.95 9.480399999999998e-59 0.0 6499.5 6485.3 6613.1 7532.0 5975.3 7288.8 6991.9 5226.1 7363.3 6008.3 False True 6406.815938137678 6470.2836863056455 6069.396445304215 8085.92840601544 5623.844601891794 6977.075015022672 7353.906370370553 5468.923684816039 6533.967615013547 7046.826649443485 0.9091774577204407 0.9181840292348654 0.8612949838610744 1.1474566933832573 0.7980676809093822 0.9901016957148618 1.0435770221410683 0.7760831870680317 0.9272212784643369 1.0 12.782758009154199 -10.327630875244147 15.951794686315509 1.0 0.9308310993471909 0.03830401912191883 0.10497688653402835 0.0 0.0 0.09812863995118094 0.02379969102452495 4.7029366072293576e-11 10.327630875244147 -0.06916890065280912 LATNT(ph)SAPDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LATNTSAPDLK 11 0 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 LATNT(0.789)S(0.21)APDLK;LATNT(0.628)S(0.372)APDLK 155.88 0.00052324 21327000.0 146208.0 135851.0 174758.0 189863.0 237707.0 200785.0 216608.0 163735.0 185880.0 157109.0 True False 170958.12666036971 149337.38947201852 178924.893493406 179225.5916541511 191130.01974397738 190255.48113820847 196089.32213388506 159437.12974157237 188598.14334958908 185591.61802584006 0.9211521968441866 0.8046558948110801 0.964078525725737 0.9656987398493254 1.0298418742023479 1.025129707698971 1.0565634602451894 0.8590750565005248 1.016199682699735 1.0 17.501772029160797 -5.42107041809099 5.085130454809665 0.9910745094601615 0.8638009791201026 0.44607364919709636 0.057118837977472685 0.1968082393324493 7.7503937061985155 0.015220224020047796 0.03246986336229002 3.7925348644474472e-06 5.42107041809099 -0.12727353034005895 LATNTS(ph)APDLK ddPTM_PC-9_AZD4547_30min_R2 4 LATNTSAPDLK 11 0 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 LAT(0.004)NT(0.421)S(0.574)APDLK;LATNT(0.065)S(0.935)APDLK;LAT(0.023)NT(0.431)S(0.546)APDLK;LATNT(0.064)S(0.936)APDLK 157.5 0.00026335 65968000.0 338409.0 375734.0 517365.0 682520.0 723840.0 731910.0 441528.0 550435.0 473287.0 542203.0 True False 446016.0226555252 497182.66762116255 510504.40205971414 525175.5588288839 623347.3103878838 686143.5519974869 480823.1366469282 465377.91848797805 498303.9845854398 523220.6380037495 0.8524434822701489 0.9502352000449945 0.9756962263710549 1.0037363220850635 1.1913660607237302 1.3113847240723135 0.9189682166999739 0.8894487042092615 0.9523783054250793 1.0 18.99705992230347 -5.1253452969616875 1.454896356026653 1.0440363393338083 0.8460863668601284 0.18361120265650432 0.12098112240504762 1.2963174975852143 3.8898283631347557 0.04104763144627859 0.3098114613171472 7.492982236747937e-06 5.1253452969616875 -0.19794997247367996 LATNTS(ph)APDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LATNTSAPDLK 11 0 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 LATNT(0.168)S(0.832)APDLK 178.22 0.0021049 11214000.0 89674.0 88675.0 118300.0 123520.0 158440.0 136300.0 121990.0 96914.0 129260.0 104300.0 True False 104854.0370577669 97478.06796734102 121120.72065524862 116599.57485724316 127394.81937105635 129152.18805756334 110434.22406888286 94370.1101888711 131150.1829641054 123208.76436165419 0.8510274216368996 0.7911618014544326 0.983052798904171 0.9463577973640649 1.03397530225297 1.0482386437904974 0.8963179254417789 0.7659366659328463 1.0644549812961421 1.0 16.910745359133287 -5.263383703937168 24.950048633325135 0.9609224549139107 0.8210946059462836 0.32643499172873747 0.08360257709081935 195.7210910899978 2511584.3043706366 0.02273456534972133 0.051546812701737534 5.452758909805906e-06 5.263383703937168 -0.13982784896762712 LATNTS(ph)APDLK ddPTM_PC-9_Lapatinib_30min_R1 4 LATNTSAPDLK 11 0 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 LAT(0.001)NT(0.215)S(0.784)APDLK;LATNT(0.08)S(0.92)APDLK;LATNT(0.017)S(0.983)APDLK;LATNT(0.079)S(0.921)APDLK 184.11 8.7963e-05 91028000.0 970280.0 764310.0 821860.0 713310.0 734080.0 723960.0 628260.0 676230.0 729550.0 609115.0 True False 956443.62927244 762540.2871540675 754289.8432713455 765769.196932403 690902.8576568089 692997.9184331866 660788.2287002102 707650.1144989849 647380.3964979195 714399.7161552801 1.338807403815583 1.067386044409239 1.0558372661886597 1.0719057967346075 0.967109647488488 0.9700422645220624 0.9249558947985121 0.9905520655962464 0.9061879251323869 1.0 19.44637198168563 -1.5228787452815138 0.6252842504619632 0.960303886296543 27.622957726780676 0.868195742292781 0.04226798103329538 64.49720073468875 0.4564312719075826 0.01825464328590252 2366.1418881403397 0.029999999999918748 1.5228787452815138 26.662653840484133 LATQSNEITIPVTFESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LATQSNEITIPVTFESR 17 0 P04792;C9J3N8 P04792 HSPB1 Heat shock protein beta-1 0 ; 244.71 8.902999999999997e-131 2304900.0 12060.1 12584.4 14327.9 13113.0 20151.8 15349.300000000001 16343.0 16905.1 11936.2 10221.6 False True 14101.636732167362 13833.69606459778 14669.531474863335 12378.321122919599 16203.199450906699 14544.355687101646 14794.87272692641 16461.35903743403 12110.744343928143 12074.69516585892 1.167866893405276 1.145676629892274 1.2148987012393728 1.0251456415992328 1.3419137484084138 1.2045319146627955 1.225279191209627 1.363293964056199 1.0029855145470796 1.0 13.55969914722293 -8.301367851865297 21.877426522130854 1.001491270594152 1.2074421596062122 0.4630549036590831 0.09020659038245024 126.36016050352448 69230.90084041283 0.08651397032041555 0.022341547024208566 4.996111799331034e-09 8.301367851865297 0.20595088901206005 LATQSNEITIPVTFESR ddPTM_PC-9_Lapatinib_30min_R1 2 LATQSNEITIPVTFESR 17 0 P04792;C9J3N8 P04792 HSPB1 Heat shock protein beta-1 0 ; 255.28 5.8003e-57 27220000.0 36945.0 36221.0 44183.0 43470.0 42806.0 42341.0 37750.0 30709.0 38174.0 39570.0 False True 36418.15752511676 36137.13249991162 40550.44429131211 46666.92881166901 40288.23523983401 40530.174131691754 39704.51028783139 32135.852248716183 33874.442129958996 46409.62177628928 0.7847113622400351 0.7786560440872654 0.8737508029429658 1.0055442605548488 0.8681009173924642 0.8733140366250229 0.8555232464341364 0.6924394342971013 0.7299012754994155 1.0 15.502136319598057 -7.55544321082673 24.900517046928336 0.7814983816247336 0.8669634330404192 0.04578838233857041 0.09601700420815157 382.6497794780993 292590.0002246144 0.0455739974695555 0.02631242207003823 2.7832792969581686e-08 7.55544321082673 0.08546505141568561 LAVDALAEGGS(ph)EAYSR ddPTM_PC-9_AZD4547_30min_R2 1 LAVDALAEGGSEAYSR 16 0 Q6ZRV2;A0A494C1T9 Q6ZRV2 FAM83H Protein FAM83H 1 LAVDALAEGGS(0.991)EAYS(0.009)R 107.73 0.0045057 0.0 8911.8 5841.1 10619.0 15383.0 9263.5 10184.0 9717.7 9592.3 9086.8 9556.8 True False 11745.567023044656 7729.1213460639 10478.185121668652 11836.687014980827 7977.422924649305 9547.192870082952 10582.556474320634 8110.030444125539 9567.109696930125 9222.219340863528 1.273616099218136 0.8380977572086438 1.136189103119675 1.2834965833584795 0.8650220331782235 1.0352381045394865 1.1475064822444063 0.8794011662886941 1.0373977611374294 1.0 13.170898263816062 -6.273704271797457 24.97009787911837 0.9977921329544165 1.1120346895546573 0.19088605387606972 0.13717398569805617 1563.3287030484923 3182775.7063298165 0.04255490821018017 0.048572345084778666 5.324707161109488e-07 6.273704271797457 0.11424255660024085 LAVDALAEGGS(ph)EAYSR ddPTM_PC-9_Lapatinib_30min_R1 1 LAVDALAEGGSEAYSR 16 0 Q6ZRV2;A0A494C1T9 Q6ZRV2 FAM83H Protein FAM83H 1 LAVDALAEGGS(0.997)EAYS(0.003)R 109.79 0.0038058999999999996 0.0 9466.5 9332.0 10135.0 10245.0 11915.0 8083.5 9772.5 8491.0 10099.0 6743.6 True False 9331.505974056514 9310.392327356367 9301.739422231369 10998.451476318132 11214.183125791304 7737.787548558853 10278.472232790256 8885.52285791948 8961.544272815423 7909.222274717829 1.1798259866693943 1.1771564894714666 1.1760624621670805 1.3905857104907973 1.4178616729027738 0.9783247049830709 1.299555364077431 1.12343825338206 1.133049996769137 1.0 12.949320124041456 -6.7626083417048415 24.999991152159062 1.126631186026468 1.2649045179303908 0.3268850740911685 0.11402068443643133 47.04945991336634 1006208.5936924603 0.04078463970750268 0.03797868193173328 1.7273950004409533e-07 6.7626083417048415 0.13827333190392288 LAVEEFVHAT(ph)SEGEAPGGCEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LAVEEFVHATSEGEAPGGCEGR 22 0 Q5C9Z4 Q5C9Z4 NOM1 Nucleolar MIF4G domain-containing protein 1 1 LAVEEFVHAT(0.799)S(0.201)EGEAPGGCEGR 79.845 0.0011419 3221200.0 5812.3 6104.1 7754.9 9480.7 10757.0 6984.8 8332.2 7797.7 7766.5 7331.6 True False 6796.20759184222 6710.074707408479 7939.806226622022 8949.52711584411 8649.243069770611 6618.504791962346 7542.913696095956 7593.018637346091 7880.070369725531 8660.761043086339 0.7847125163749271 0.7747673298023802 0.9167561819477936 1.0333418820033473 0.9986700968588758 0.7641943657186716 0.8709296629442592 0.876714944514882 0.9098588831308292 1.0 13.08027808846457 -1.5228790698964396 0.019429726481924082 1.5926533877519948 4.353427100762247e-07 0.17502825777096898 0.08433214399343689 7854.281261666274 11.808488398008588 362.214045669173 642.7358193847236 0.029999977576322456 1.5228790698964396 -1.5926529524092847 LAVEEFVHATS(ph)EGEAPGGCEGR ddPTM_PC-9_AZD4547_30min_R2 4 LAVEEFVHATSEGEAPGGCEGR 22 0 Q5C9Z4 Q5C9Z4 NOM1 Nucleolar MIF4G domain-containing protein 1 1 LAVEEFVHAT(0.013)S(0.987)EGEAPGGCEGR;LAVEEFVHAT(0.006)S(0.994)EGEAPGGCEGR;LAVEEFVHAT(0.025)S(0.975)EGEAPGGCEGR;LAVEEFVHAT(0.013)S(0.987)EGEAPGGCEGR 122.44 3.6452e-07 15956500.0 47701.6 52774.8 91502.0 113903.0 84192.0 77164.0 80617.0 92298.0 72325.0 74366.0 True False 62869.71654508258 69833.22203253732 90288.62369365532 87644.42313380755 72503.3940597048 72338.9228816853 87791.75682417705 78035.4648970425 76147.95184558615 71762.46897524872 0.8760807347189615 0.97311621283018 1.2581593830724578 1.2213128169271406 1.0103246877516385 1.0080328048166152 1.2233658913610808 1.0874133235850258 1.0611110923712785 1.0 16.130941906332154 -5.034642393827536 7.583745948585878 1.1132673384244889 0.8989121158194037 0.4117313420476999 0.09122284259560835 0.193409587115053 38.07523786453366 0.024088473879487413 0.06810442821195577 9.233314025123458e-06 5.034642393827536 -0.21435522260508522 LAVEEFVHATS(ph)EGEAPGGCEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LAVEEFVHATSEGEAPGGCEGR 22 0 Q5C9Z4 Q5C9Z4 NOM1 Nucleolar MIF4G domain-containing protein 1 1 LAVEEFVHAT(0.16)S(0.84)EGEAPGGCEGR;LAVEEFVHAT(0.001)S(0.999)EGEAPGGCEGR;LAVEEFVHAT(0.053)S(0.947)EGEAPGGCEGR 148.26 2.7275e-05 6387500.0 27237.0 28084.4 48771.2 46706.3 52926.0 41360.1 45866.8 55671.7 47459.3 34457.0 True False 31847.686144728665 30872.433628666444 49934.090373806 44089.49743486767 42555.53023246998 39191.10354570521 41521.96465712467 54210.37686404195 48153.30247832554 40703.78133853807 0.7824257377919699 0.7584659855529596 1.226767851332985 1.0831793996771504 1.0454932891499857 0.9628369221952195 1.0201009167129136 1.3318265547165742 1.1830179136878938 1.0 15.31287520512088 -5.249879000430018 24.857499485145546 1.1072537715080055 0.7704457954037671 0.6111018569672633 0.10728138654980335 481.47214063658254 1035271.8545696007 0.029598138553906528 0.07685009326512832 5.62498021950375e-06 5.249879000430018 -0.3368079761042384 LAVEEFVHATS(ph)EGEAPGGCEGR ddPTM_PC-9_Lapatinib_30min_R1 3 LAVEEFVHATSEGEAPGGCEGR 22 0 Q5C9Z4 Q5C9Z4 NOM1 Nucleolar MIF4G domain-containing protein 1 1 LAVEEFVHAT(0.003)S(0.997)EGEAPGGCEGR;LAVEEFVHAT(0.272)S(0.728)EGEAPGGCEGR;LAVEEFVHAT(0.005)S(0.995)EGEAPGGCEGR 182.67 2.888e-14 4367300.0 31140.8 43175.0 56424.0 36589.1 48910.0 53627.0 51036.0 45934.0 51304.2 35170.7 True False 30696.72648147668 43075.03094016411 51785.03652293862 39279.9844716595 46033.20996075973 51333.49822064272 53678.39435893415 48068.26133031132 45525.780738823356 41249.90863298805 0.744164714511104 1.0442454872667641 1.2553976054513125 0.9522441569784914 1.1159590769116616 1.2444511981195203 1.301297291020104 1.1652937648417128 1.1036577351935233 1.0 15.332103303395636 -4.807301392102666 3.1909319779065526 1.1502277652220785 0.6970587255076116 0.5663643265815925 0.1043460233015736 0.23279664702734018 3.7219230879705165 0.027429478276313445 0.2574820730050237 1.5584705785404426e-05 4.807301392102666 -0.45316903971446687 LAVLSS(ph)SLTHWK ddPTM_PC-9_AZD4547_30min_R2 1 LAVLSSSLTHWK 12 0 F5GX19;F5H3Y3;Q6IAA8 F5GX19 LAMTOR1 Ragulator complex protein LAMTOR1 1 LAVLS(0.133)S(0.506)S(0.228)LT(0.133)HWK 62.081 0.030124 9240000.0 30097.0 38353.0 72222.0 73200.0 58681.0 57272.0 58184.0 70708.0 51733.0 54784.0 True False 39667.21994351027 50749.85721620738 71264.28909098345 56324.87092872627 50534.15605779085 53690.77278627172 63362.26328265659 59781.70330819809 54467.50076498726 52866.0288349518 0.7503347767495772 0.9599710501170586 1.34801668787098 1.06542655406505 0.9558909033163607 1.0156006412718228 1.198544030618871 1.1308150928990162 1.0302930249411255 1.0 15.690053338662912 -4.915958187832336 4.239581192414998 1.0963123474445942 0.7625220737725886 0.4839044848024996 0.10854170078730119 0.1864911217725036 5.952140696551351 0.02820852539276653 0.13892143024568637 1.2135056764033783e-05 4.915958187832336 -0.33379027367200553 LAVLSS(ph)SLTHWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LAVLSSSLTHWK 12 0 F5GX19;F5H3Y3;Q6IAA8 F5GX19 LAMTOR1 Ragulator complex protein LAMTOR1 1 LAVLS(0.076)S(0.465)S(0.235)LT(0.224)HWK 72.891 0.013576 8469100.0 37114.0 41261.0 53255.0 44001.0 83437.0 57154.0 53442.0 45613.0 52443.0 42328.0 True False 43396.66716508647 45357.11939555077 54524.8011707122 41535.76662316675 67088.11880751605 54156.743626133284 48379.58687342602 44415.70708096839 53209.87966259141 50001.731331736395 0.8679032907315021 0.9071109777105325 1.0904582645142327 0.8306865685829514 1.3417159170433528 1.0830973685057117 0.9675582341829674 0.8882833833551175 1.0641607449464212 1.0 15.609690429246138 -5.128669518769939 5.08959082124185 1.0322050325971108 0.8770561141664864 0.16893488782121224 0.1302334045555363 0.3945066855188798 14.333997171397005 0.03413253958759753 0.09733242459220956 7.43584761778816e-06 5.128669518769939 -0.1551489184306244 LAVLSSS(ph)LTHWK ddPTM_PC-9_AZD4547_30min_R2 1 LAVLSSSLTHWK 12 0 F5GX19;F5H3Y3;Q6IAA8 F5GX19 LAMTOR1 Ragulator complex protein LAMTOR1 1 LAVLS(0.021)S(0.171)S(0.574)LT(0.234)HWK 94.68799999999999 0.0027377 12108000.0 73984.0 69917.0 142450.0 137440.0 112430.0 83464.0 105470.0 172140.0 100030.0 99784.0 True False 97509.3730372017 92516.3029485457 140561.01992482334 105755.33142683246 96821.03518306487 78244.9828857622 114856.62567753662 145539.71838367937 105317.3815847075 96290.59253188598 1.012657316496543 0.9608031326415355 1.4597585935331898 1.0982934952011256 1.005508769208199 0.8125921840168541 1.1928125339918603 1.5114635246998285 1.093745285136057 1.0 16.555107235037056 -7.50953651968606 24.86546348817674 1.2519902401476564 1.0657753795742309 0.09226649575273493 0.1984241994133154 1155.21145392371 2152941.0163143314 0.08846223944434499 0.05665303890899612 3.0935951650717326e-08 7.50953651968606 -0.1862148605734255 LAVLSSS(ph)LTHWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LAVLSSSLTHWK 12 0 F5GX19;F5H3Y3;Q6IAA8 F5GX19 LAMTOR1 Ragulator complex protein LAMTOR1 1 LAVLS(0.025)S(0.157)S(0.618)LT(0.201)HWK 85.837 0.0053546999999999996 6518100.0 34822.0 37982.0 60776.0 45016.0 89248.0 52667.0 53159.0 42688.0 49828.0 39508.0 True False 40716.67683414994 41752.601945706796 62225.13033426355 42493.89946384111 71760.49507212872 49905.049805045346 48123.3946821686 41567.48523167469 50556.640234685365 46670.48765484408 0.8724287848730851 0.8946253627022721 1.3332864827651958 0.9105090089931925 1.5375989983828777 1.0693063713866195 1.0311311730460078 0.8906589007402469 1.083267880305466 1.0 15.510222921493666 -7.2750950136089765 4.041018119976333 0.9889822232917574 1.1158810366362744 0.05860112804427675 0.19916317528566282 0.641891726405563 24.859201787773195 0.08632404795121562 0.059827873460102356 5.307683116716087e-08 7.2750950136089765 0.12689881334451691 LAVLSSS(ph)LTHWK ddPTM_PC-9_Lapatinib_30min_R1 1 LAVLSSSLTHWK 12 0 F5GX19;F5H3Y3;Q6IAA8 F5GX19 LAMTOR1 Ragulator complex protein LAMTOR1 1 LAVLS(0.005)S(0.028)S(0.69)LT(0.277)HWK 85.536 0.0054476 6557400.0 74219.0 66812.0 57035.0 31580.0 47783.0 55457.0 40768.0 38212.0 72976.0 26377.0 True False 73160.62344990222 66657.30091891719 52345.80246146682 33902.49854779175 44972.49788499252 53085.23338658108 42878.76756064398 39987.469019764336 64756.67440865218 30936.22930485678 2.3648849615430185 2.1546679222620204 1.6920550318408998 1.0958833480869399 1.4537162057410835 1.715956811137518 1.386037294270776 1.2925773411398451 2.0932310066141713 1.0 14.917009742635745 -5.287611389938411 2.844954245528377 1.4539622108530803 2.313452150224408 0.5533811211972888 0.293405558677097 0.19507064189501802 3.1064691773200432 0.07715714004771404 0.22492572298577757 5.1568988148651915e-06 5.287611389938411 0.8594899393713276 LAVPTEVSTEVPEMDT(ph)ST ddPTM_PC-9_AZD4547_30min_R2 1 LAVPTEVSTEVPEMDTST 18 0 O00488 O00488 ZNF593 Zinc finger protein 593 1 LAVPTEVSTEVPEMDT(0.362)S(0.275)T(0.362) 82.171 0.021359 0.0 8095.4 6789.2 9845.5 13932.0 12830.0 10824.0 7651.1 11709.0 8879.2 8019.2 True False 10669.568805219562 8983.67612995789 9714.942237064577 10720.192647254298 11048.775961920504 10147.173568909846 8332.033077855316 9899.643096052665 9348.536384753932 7738.450248854514 1.378773328264135 1.1609141160127896 1.255411862149354 1.3853151861822923 1.4277763126481302 1.3112668871150117 1.0767056464682534 1.2792798012131772 1.2080631242848336 1.0 12.917828956696264 -8.873753364645367 0.5202237586508692 0.9913816180812314 1.3094125470731883 0.47298532786452996 0.0955775539016797 1.52427919461048 0.8291736494434918 0.14301125487557179 0.05292866484088316 1.3373547832309302e-09 8.873753364645367 0.31803092899195695 LAVYIDR ddPTM_PC-9_AZD4547_30min_R2 1 LAVYIDR 7 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 125.86 0.021088 7209900.0 31499.0 26535.0 38575.0 45761.0 52662.0 36079.0 26898.0 40548.0 37627.0 30772.0 False True 41515.026780098684 35111.91982979332 38063.47029554275 35211.50845040227 45350.79031228817 33822.97442652426 29291.8698916695 34282.23830034533 39615.88640295704 29694.681646267843 1.3980626993964245 1.182431259848389 1.2818278622740087 1.1857850126110985 1.5272361176496416 1.139024651937135 0.9864348855664876 1.1544908515513272 1.3341071264839148 1.0 14.8579169452686 -6.960963981193443 24.999922496947256 1.1217887831212074 1.302116805801815 0.35424065738839816 0.12940454621489936 194.24621702358752 124400.96190626097 0.045424619690897804 0.04006069909887502 1.094047098801279e-07 6.960963981193443 0.18032802268060766 LAVYIDR ddPTM_PC-9_Lapatinib_30min_R1 1 LAVYIDR 7 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 110.36 0.043661 8729600.0 42528.0 28949.0 33325.0 34801.0 33874.0 41365.0 32250.0 30310.0 30111.0 32524.0 False True 41921.542921319946 28881.970369121256 30585.147138220065 37360.38163273276 31881.597918846364 39595.91537652463 33919.747199538084 31718.313252095093 26719.582097113078 38145.7300644941 1.0989838928352393 0.757148187235889 0.8017973987261187 0.9794118914375599 0.8357841851484613 1.0380169762009708 0.8892147860897924 0.8315036361466412 0.7004606295891441 1.0 15.219233954052354 -7.7242936734230945 4.814359097565908 0.8236806587941228 0.9090183974013877 0.060354838775184105 0.12001575489139682 0.4938176940989824 26.327858026466846 0.05989894889121156 0.031906468151196944 1.8867151057064852e-08 7.7242936734230945 0.0853377386072649 LAYIAHPK ddPTM_PC-9_AZD4547_30min_R2 1 LAYIAHPK 8 0 A0A3B3ITT5;P47914 A0A3B3ITT5 RPL29 60S ribosomal protein L29 0 78.49600000000001 0.018502 3907800.0 46490.0 40573.0 63787.0 89468.0 74456.0 56606.0 50853.0 63050.0 47261.0 60096.0 False True 61272.852947928164 53687.428801741225 62941.14270231458 68842.5348668208 64119.06960411173 53066.41787155496 55378.818484685406 53307.07124486468 49759.11997475622 57992.05733179877 1.0565731889344514 0.9257721017650948 1.0853407448920092 1.1871028212181116 1.1056526109645939 0.9150635503054839 0.9549379869011743 0.9192133146763674 0.8580333629148869 1.0 15.82356769991554 -6.76715818201696 24.965859081763504 0.9259934720642297 1.0710855643331583 0.5179246609168908 0.06876298449731916 124.71222644304247 544437.3816135455 0.026266772858425973 0.023794269892456314 1.7093925938073827e-07 6.76715818201696 0.1450920922689286 LAYIAHPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LAYIAHPK 8 0 A0A3B3ITT5;P47914 A0A3B3ITT5 RPL29 60S ribosomal protein L29 0 83.61399999999999 0.012426000000000001 2551200.0 64135.0 52632.0 58151.0 81515.0 82609.0 67879.0 84398.0 77470.0 69794.0 55323.0 False True 74991.78877600959 57856.95712722973 59537.5403788956 76947.97882519556 66422.35946366825 64319.30574584985 76403.2104513942 75436.49458625003 70814.60521272446 65352.621963373 1.1474947220639269 0.8853042982675703 0.9110199191742228 1.1774275692920355 1.0163687005686595 0.9841886035100126 1.1690917388779676 1.1542994346658129 1.0835771096133318 1.0 15.995957498013514 -6.316297867450565 0.9350094847556146 1.098711127212894 0.9907931267135642 0.0765230197616733 0.09905581155415592 1.1995742358517532 2.24720726214007 0.050280390300869296 0.07546829717437188 4.827276024335134e-07 6.316297867450565 -0.10791800049932976 LAYIAHPK ddPTM_PC-9_Lapatinib_30min_R1 1 LAYIAHPK 8 0 A0A3B3ITT5;P47914 A0A3B3ITT5 RPL29 60S ribosomal protein L29 0 98.41799999999999 0.0046265 9075700.0 156710.0 152260.0 156950.0 153610.0 159070.0 152130.0 157150.0 132240.0 160600.0 131190.0 False True 154475.28666290536 151907.45132482616 144046.17684452038 164906.99182793836 149713.81534365256 145623.75453235078 165286.45805914464 138384.35316585493 142511.53680702607 153866.016700313 1.0039597435200982 0.9872709684861631 0.9361792807380017 1.0717570738776583 0.9730141752824619 0.9464322119677941 1.0742232859714267 0.8993821776473754 0.9262054082065295 1.0 17.23131510342772 -7.791805773965211 24.999965695601166 0.9345953679429573 0.9958910096390212 0.21524649087100012 0.049146904705317435 298.91722551382014 246087.91838039225 0.025853406119475345 0.012421897630105917 1.6150806949103658e-08 7.791805773965211 0.06129564169606394 LAYINPDLALEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LAYINPDLALEEK 13 0 P31948-2;P31948;P31948-3 P31948-2 STIP1 Stress-induced-phosphoprotein 1 0 84.821 0.038692000000000004 1933300.0 14115.0 13275.0 14282.0 18398.0 19420.0 18015.0 17862.0 18005.0 16549.0 16489.0 False True 16504.390716042348 14592.854268581375 14622.537044786626 17367.219707120792 15614.790407636458 17070.261686405 16169.982050318764 17532.387827874416 16790.99781736791 19478.32517314783 0.8473208332508356 0.7491842413996969 0.7507081288972816 0.8916177111090979 0.8016495396207106 0.876372148768596 0.8301525878934479 0.9000972964577048 0.862034988537691 1.0 14.249582013423955 -13.373470554769654 0.09416496121482296 1.4623519079289085 0.6879787833664748 0.6292663737956767 0.04319837129661097 93.53673847397317 0.7713248067400541 9.286016799827765 0.938764281871532 4.231842006956103e-14 13.373470554769654 -0.7743731245624337 LAYINPDLALEEK ddPTM_PC-9_Lapatinib_30min_R1 2 LAYINPDLALEEK 13 0 P31948-2;P31948;P31948-3 P31948-2 STIP1 Stress-induced-phosphoprotein 1 0 ; 205.02 4.1242e-09 14266700.0 83856.0 77216.0 84083.0 84175.0 76761.0 73768.0 75734.0 73471.0 67493.0 76471.0 False True 82660.19806269309 77037.21109613686 77170.02030976607 90365.51029956821 72246.06889793256 70613.1146016069 79655.13595069207 76884.73087907213 59891.22760720178 89688.91045879746 0.9216323137370108 0.8589379746287283 0.8604187509359645 1.007543851712655 0.8055184139082833 0.7873115443190285 0.8881269216363729 0.8572378735093734 0.6677662522694536 1.0 16.452641994402555 LAYYET(ph)T(ph)LNLT(ph)LDY(ph)RMHEK ddPTM_PC-9_Lapatinib_30min_R1 1 LAYYETTLNLTLDYRMHEK 19 1 Q9UN88 Q9UN88 GABRQ Gamma-aminobutyric acid receptor subunit theta 4 LAY(0.059)Y(0.222)ET(0.863)T(0.863)LNLT(0.997)LDY(0.997)RMHEK 40.515 0.034989 1418900.0 5889.4 10444.0 7413.7 9629.7 10384.0 9465.4 9137.9 8258.0 10478.0 9772.8 True False 5805.416076016317 10419.817559677453 6804.17420370959 10337.900261737506 9773.23353572949 9060.586906925095 9611.015749911905 8641.696827311156 9297.857301768492 11462.015458562546 0.5064917332387174 0.9090737660708237 0.5936280777414781 0.9019269167024824 0.8526627425221737 0.7904881074084142 0.8385101018802172 0.7539421717369515 0.8111886897537424 1.0 13.484573126647483 -2.461654163330125 0.05882800400745966 1.2361304021789243 1.0881744190932695e-28 0.3313753318533347 0.11489670015780311 399.38877540990245 2.0989932475589748 10.324133681912496 44.66855082323487 0.0034541869309339095 2.461654163330125 -1.2361304021789243 LCAGIMITAS(ph)HNPK ddPTM_PC-9_AZD4547_30min_R2 4 LCAGIMITASHNPK 14 0 Q96G03;Q96G03-2 Q96G03 PGM2 Phosphoglucomutase-2 1 LCAGIMIT(0.019)AS(0.981)HNPK;LCAGIMIT(0.002)AS(0.998)HNPK;LCAGIMIT(0.001)AS(0.999)HNPK;LCAGIMIT(0.001)AS(0.999)HNPK 125.67 1.9427e-05 125659000.0 459771.0 408483.0 504249.0 530535.0 540739.0 529315.0 589223.0 685264.0 532954.0 564098.0 True False 605968.6141691079 540517.1414295638 497562.32878955675 408228.3524340414 465666.7236845623 496216.84937430813 641662.7055237993 579372.1946001735 561124.8603928449 544349.1007180694 1.1131985216284075 0.9929604746596427 0.9140500611339404 0.7499385080190883 0.8554560356034125 0.9115783395613801 1.1787705806390794 1.064339398808419 1.030818016696723 1.0 19.054172648599348 -7.233543807435707 23.587753517723343 1.0738436086249652 0.914724998203128 0.3475045750181257 0.0972596376772004 415.4966315778903 351332.98580066976 0.040625122770450474 0.03145840171861867 5.840582899581783e-08 7.233543807435707 -0.15911861042183717 LCAGIMITAS(ph)HNPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LCAGIMITASHNPK 14 0 Q96G03;Q96G03-2 Q96G03 PGM2 Phosphoglucomutase-2 1 LCAGIMIT(0.002)AS(0.998)HNPK;LCAGIMIT(0.005)AS(0.995)HNPK 97.823 0.0018070999999999999 116829000.0 297870.0 300140.0 271600.0 351830.0 366710.0 286730.0 316490.0 323840.0 281860.0 259040.0 True False 348293.5077993293 329935.9156438429 278075.97404873616 332118.10574824974 294855.80794976105 271693.374040683 286509.77601082675 315339.54313684243 285981.6692732682 306001.90144048794 1.1382070051191049 1.0782152466722816 0.9087393664539601 1.0853465425699027 0.9635750842126888 0.8878813261018988 0.9363006395126859 1.0305149793265924 0.9345748112251082 1.0 18.223181092028724 -5.0707021227015305 4.623756758309472 0.9697296186757683 1.1270758607687168 0.5133452681068899 0.05574903371933884 0.15746021389457315 6.3067195663473345 0.014545438736217484 0.04478182554573404 8.49763117377868e-06 5.0707021227015305 0.15734624209294845 LCAGIMITAS(ph)HNPK ddPTM_PC-9_Lapatinib_30min_R1 4 LCAGIMITASHNPK 14 0 Q96G03;Q96G03-2 Q96G03 PGM2 Phosphoglucomutase-2 1 LCAGIMIT(0.015)AS(0.985)HNPK;LCAGIMIT(0.009)AS(0.991)HNPK;LCAGIMIT(0.005)AS(0.995)HNPK;LCAGIMIT(0.002)AS(0.998)HNPK 96.435 0.0019666 64683000.0 340862.0 359989.0 421568.0 368976.0 392927.0 401754.0 371912.0 366493.0 378193.0 355090.0 True False 336001.2453735645 359155.467588159 386908.3063395393 396111.72590785293 369815.8063842044 384571.9179543163 391167.783580608 383521.60272847494 335596.92179115536 416466.83337231673 0.8067899252692304 0.862386722803153 0.929025495755739 0.9511243013047654 0.8879838122753779 0.9234154730648462 0.939253146314555 0.9208935069881324 0.8058190830556138 1.0 18.667842081109157 -4.977560324491258 2.804874334560901 0.9175127039310271 0.8052902069867348 0.370389170990437 0.0469616101113112 0.3255352099070101 4.623088270913951 0.011917355627734444 0.06880533652030316 1.0530274090687391e-05 4.977560324491258 -0.11222249694429232 LCDDGPQLPT(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 2 LCDDGPQLPTSPR 13 0 O60504-2;O60504;H0YAZ3;H0YB51 O60504-2 SORBS3 Vinexin 1 LCDDGPQLPT(0.832)S(0.168)PR;LCDDGPQLPT(0.924)S(0.076)PR 219.97 1.9693000000000002e-14 156937000.0 238731.0 272486.0 335128.0 306792.0 360364.0 323702.0 317569.0 348584.0 366933.0 274924.0 True False 235326.65216209623 271855.0754084894 307575.0694714896 329354.507108111 339168.09802288335 309858.0200462173 334011.1689429491 364780.48520845576 325605.14156421256 322444.2470867967 0.7298212149486735 0.8431072281941209 0.9538860508455449 1.0214308677662782 1.051865868556138 0.9609661913515506 1.0358726259210909 1.1312978553785853 1.0098029178872745 1.0 18.298690204260026 -4.970250568889615 1.07339095430197 1.0388433647686024 0.6299687059857418 0.8517246355974837 0.04150350131925701 0.4810372759304974 0.5655738467706121 0.014111653050687767 0.20878004158096358 1.0709012638502973e-05 4.970250568889615 -0.40887465878286056 LCDDGPQLPTS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 5 LCDDGPQLPTSPR 13 0 O60504-2;O60504;H0YAZ3;H0YB51 O60504-2 SORBS3 Vinexin 1 LCDDGPQLPT(0.079)S(0.921)PR;LCDDGPQLPT(0.142)S(0.858)PR;LCDDGPQLPT(0.034)S(0.966)PR;LCDDGPQLPT(0.001)S(0.999)PR;LCDDGPQLPT(0.003)S(0.997)PR 193.45 1.4387e-06 386429600.0 358665.0 418827.0 606607.0 747826.0 668930.0 608950.0 547710.0 719541.0 554160.0 567760.0 True False 472713.0093045532 554204.6371416189 598562.9948300276 575426.2694965258 576060.6160722909 570872.2602353712 596455.1289451382 608352.4718572759 583451.7662599382 547882.8952126947 0.8627993562767466 1.0115384911340772 1.0925017007469422 1.0502723748532767 1.0514301890163178 1.0419603627409317 1.0886544080073666 1.1103695281837669 1.0649205721843813 1.0 19.063508038151845 -4.794982139669927 2.8018388889679957 1.0656626017259594 0.8287728902178546 0.8053624429403683 0.02949014100353416 0.16663933246494625 1.8438459263793228 0.007558828386512158 0.09091905394004603 1.6033113253999268e-05 4.794982139669927 -0.23688971150810478 LCDDGPQLPTS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LCDDGPQLPTSPR 13 0 O60504-2;O60504;H0YAZ3;H0YB51 O60504-2 SORBS3 Vinexin 1 LCDDGPQLPT(0.001)S(0.999)PR;LCDDGPQLPT(0.002)S(0.998)PR;LCDDGPQLPT(0.023)S(0.977)PR;LCDDGPQLPT(0.049)S(0.951)PR;LCDDGPQLPT(0.008)S(0.992)PR 225.33 1.8429000000000002e-19 247983000.0 277620.0 368996.0 495299.0 518227.0 594100.0 518900.0 592903.0 530524.0 504675.0 416413.0 True False 324615.5827550605 405627.4842703923 507108.806591918 489192.42130460386 477690.3697825355 491687.9705287571 536738.9355940062 516598.30713664193 512054.91712370276 491905.38057650655 0.6599146819142645 0.8246046908350592 1.0309072163382178 0.9944847944766875 0.971102144121068 0.99955802466016 1.0911426400031554 1.0501985290975993 1.0409622202619155 1.0 18.908021310121327 -4.9794502900356 2.0008912836410997 1.0253282672577915 0.6216034661177683 0.9226861899926522 0.03398424159554842 0.13278721320670847 0.7898896136150028 0.010383188537259341 0.0857770240619031 1.048454794340854e-05 4.9794502900356 -0.4037248011400232 LCDDGPQLPTS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 LCDDGPQLPTSPR 13 0 O60504-2;O60504;H0YAZ3;H0YB51 O60504-2 SORBS3 Vinexin 1 LCDDGPQLPT(0.026)S(0.974)PR 198.48 6.8071e-07 83056000.0 127610.0 154320.0 179850.0 148540.0 143430.0 183470.0 175250.0 161690.0 172850.0 128940.0 True False 125790.25799919228 153962.68152139263 165063.42724107622 159464.12711491407 134993.72939422948 175623.41578945896 184323.58749516436 169202.70767836532 153381.81280880747 151227.10719825 0.8317970258750537 1.0180891797365166 1.0914936501740233 1.0544678799275435 0.892655634927014 1.1613223253634468 1.2188528294304193 1.1188649364068726 1.014248144069388 1.0 17.2063572377743 -6.777206679697916 24.999748700293868 1.117348913662315 0.9905311392932479 0.30045604138529547 0.0929819850513855 317.8016499081895 503885.3516809719 0.03382485227505146 0.029930011960405453 1.6702955355153158e-07 6.777206679697916 -0.12681777436906705 LCDFGSASHVADNDITPY(ph)LVSR ddPTM_PC-9_AZD4547_30min_R2 6 LCDFGSASHVADNDITPYLVSR 22 0 Q13523;H0YDJ3 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 LCDFGSASHVADNDIT(0.163)PY(0.834)LVS(0.003)R;LCDFGSASHVADNDIT(0.055)PY(0.941)LVS(0.005)R;LCDFGSASHVADNDIT(0.367)PY(0.627)LVS(0.006)R;LCDFGSASHVADNDIT(0.008)PY(0.989)LVS(0.002)R;LCDFGSASHVADNDIT(0.066)PY(0.923)LVS(0.011)R;LCDFGSASHVADNDIT(0.002)PY(0.954)LVS(0.044)R 192.22 4.4749e-16 364593000.0 81613.0 75539.90000000001 218026.0 375902.0 288340.0 241325.0 162295.8 285728.0 186646.0 233653.0 True False 107564.23634414423 99956.6954117431 215134.83278434217 289243.60152800666 248308.96811069027 226234.9096006256 176739.8117913749 241575.30297625178 196511.7265146388 225472.87958843846 0.47706064046586905 0.44332025915576484 0.9541494887413218 1.2828310085717207 1.1012808660799256 1.003379696988738 0.7838628402403992 1.0714162315982547 0.8715537180051844 1.0 17.782594387579174 -5.290106231822985 5.1607630120162735 1.0188497129064853 0.45561132054673736 0.7520399620622475 0.12615054156861571 0.08483116140632804 6.516299380322622 0.03547934884049364 0.08124682174201957 5.127359494321264e-06 5.290106231822985 -0.5632383923597479 down LCDFGSASHVADNDITPY(ph)LVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LCDFGSASHVADNDITPYLVSR 22 0 Q13523;H0YDJ3 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 LCDFGSASHVADNDIT(0.194)PY(0.555)LVS(0.251)R;LCDFGSASHVADNDIT(0.003)PY(0.894)LVS(0.104)R;LCDFGSASHVADNDIT(0.065)PY(0.934)LVS(0.001)R;LCDFGSASHVADNDIT(0.312)PY(0.683)LVS(0.005)R;LCDFGSASHVADNDIT(0.001)PY(0.997)LVS(0.002)R;LCDFGSASHVADNDIT(0.305)PY(0.694)LVS(0.001)R 203.23 1.7115000000000002e-24 241444100.0 108685.4 130655.4 248223.0 278995.0 312266.0 276325.0 253058.0 227037.9 252858.4 182763.4 True False 127083.69158550136 143626.00464054325 254141.57771096966 263363.8146639937 251079.7189202374 261834.0305576388 229086.51425873765 221078.39569153896 256555.97573890546 215896.95766572165 0.5886312292657131 0.6652525639704603 1.1771429317890763 1.2198588507753134 1.1629608940992584 1.212773136724986 1.0610919057666282 1.0239995879601038 1.1883260353123508 1.0 17.71998338805429 -5.231329130434959 5.875380437881475 1.1367756806281588 0.6182468264221908 0.8765782105077022 0.07564272257885196 0.05784650069946999 6.397255021219376 0.020088212689484724 0.052541443368268055 5.870442919005585e-06 5.231329130434959 -0.5185288542059681 LCDFGSASHVADNDITPY(ph)LVSR ddPTM_PC-9_Lapatinib_30min_R1 7 LCDFGSASHVADNDITPYLVSR 22 0 Q13523;H0YDJ3 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 LCDFGSASHVADNDIT(0.024)PY(0.896)LVS(0.08)R;LCDFGSASHVADNDIT(0.16)PY(0.84)LVSR;LCDFGSASHVADNDIT(0.055)PY(0.94)LVS(0.004)R;LCDFGSASHVADNDIT(0.04)PY(0.869)LVS(0.091)R;LCDFGSASHVADNDIT(0.036)PY(0.712)LVS(0.252)R;LCDFGSASHVADNDIT(0.262)PY(0.726)LVS(0.012)R;LCDFGSASHVADNDIT(0.287)PY(0.712)LVS(0.001)R 166.21 6.6823e-16 241134000.0 188591.0 138329.30000000002 302491.3 189158.2 244206.8 268648.1 181145.4 204564.0 321219.0 173368.5 True False 185901.65775664593 138009.00700477685 277621.6329641857 203069.52504125712 229843.0361530414 257158.64701230844 190524.22246075046 214068.79023759754 285039.9336339733 203335.01422599502 0.9142628900599828 0.6787272105107677 1.365341006422167 0.9986943262784892 1.1303662432559907 1.264704202526042 0.936996626901621 1.0527886259651893 1.4018241507444853 1.0 17.633499142647658 -5.249729066292224 24.99440630526985 1.1369891308953886 0.7964950369842305 0.43390714880264925 0.1585414670941707 674.4916617406169 1439623.6247526896 0.03872469247502284 0.10060836281781177 5.626922501050594e-06 5.249729066292224 -0.34049409391115804 LCDFGSASHVADNDITPYLVSR ddPTM_PC-9_AZD4547_30min_R2 1 LCDFGSASHVADNDITPYLVSR 22 0 Q13523;H0YDJ3 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 0 119.18 9.0476e-07 3561400.0 1761.1 1669.8 12688.0 17660.0 14866.0 12349.0 5855.1 14177.0 8817.0 13672.0 False True 2321.093166844401 2209.530195281284 12519.74882980808 13588.75984428015 12802.112505838679 11576.815077833304 6376.192557168343 11986.270405050696 9283.048619737745 13193.34744143293 0.17592905645425091 0.16747305451400335 0.9489440708951958 1.0299705896932154 0.9703460446766071 0.8774736759737713 0.4832884592385012 0.9085086600090982 0.7036158685994184 1.0 13.687523033937905 -5.2570395906361105 24.936936058290343 0.8584296329465003 0.17170096242605742 0.7638791587638118 0.15420479407921725 170.95208684677368 968905.7900081163 0.042191965222346306 0.10392612714231535 5.532996676715613e-06 5.2570395906361105 -0.686728670520443 LCEGFNEVLK ddPTM_PC-9_Lapatinib_30min_R1 1 LCEGFNEVLK 10 0 Q9Y6H1 Q9Y6H1 CHCHD2 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 0 91.069 0.038276 2479800.0 15886.0 12627.0 9990.6 10393.0 11808.0 11920.0 12326.0 12490.0 15469.0 9926.8 False True 15659.462726864387 12597.762957300563 9169.211432831244 11157.33589003166 11113.476655421204 11410.20938687716 12964.17996841881 13070.330996986719 13726.718324208501 11642.634153370434 1.3450102889586304 1.0820371740061614 0.7875547158867688 0.958317142242395 0.9545500192672425 0.9800367542747198 1.1135091765007321 1.1226266173796227 1.1790045228067862 1.0 13.50712988539566 -7.270940092237807 21.49955152705923 1.1140040378208655 1.0047716976414434 0.07817791139824559 0.1383850119285579 243.2255284344545 550394.1608854074 0.06050516323253038 0.041575953066509345 5.358705718595981e-08 7.270940092237807 -0.10923234017942218 LCFEGLR ddPTM_PC-9_Lapatinib_30min_R1 1 LCFEGLR 7 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 110.34 0.043677999999999995 3714700.0 42532.0 33108.0 42157.0 35891.0 42641.0 37406.0 36664.0 26466.0 39348.0 31923.0 False True 41925.485880586464 33031.34046014946 38691.01419072598 38530.54386886615 40132.94021543153 35806.232577644885 38562.282521670204 27695.70697888316 34916.213887190934 37440.84801527626 1.1197792812673588 0.8822273589175206 1.033390434290902 1.0291044650790304 1.0719025434214757 0.9563413885026207 1.0299521663060727 0.739719008703623 0.9325700601905372 1.0 15.192325491115493 -7.712649193495461 24.999863043053146 0.8771071772466444 1.013117798114537 0.3110813102432096 0.0855526191178603 114.18700050184053 58508.677345204094 0.037844337048879725 0.021849382268354135 1.9379867635993748e-08 7.712649193495461 0.1360106208678925 LCNLEEGSPGS(ph)GTYTR ddPTM_PC-9_AZD4547_30min_R2 1 LCNLEEGSPGSGTYTR 16 0 R4GNH9;R4GMQ7;B1AMU7;B1AMU3;B1AMU4;Q9Y3B2 R4GNH9 EXOSC1 Exosome complex component CSL4 1 LCNLEEGS(0.302)PGS(0.498)GT(0.198)YT(0.001)R 91.65700000000001 0.018308 0.0 5577.0 3281.4 5810.8 10056.0 11697.0 6946.4 8451.8 11974.0 6809.8 6346.4 True False 7350.369991193701 4342.0483787256 5733.744995290728 7737.744563651254 10073.073454916917 6512.040509892401 9203.993826693884 10123.693435146857 7169.752125517765 6124.214467693821 1.2002143344208536 0.7089967867112716 0.9362417050443156 1.2634672747776967 1.6447943663720366 1.0633266591567658 1.5028856150035856 1.6530599129979702 1.1707219208829667 1.0 12.580309091023711 -5.82417102195581 4.204379846137001 1.3721998132842852 0.9213043734203921 0.3430045501535858 0.23866572957365365 0.20103388280837772 7.058522524518504 0.06561511179896336 0.10354828291556602 1.499094386967551e-06 5.82417102195581 -0.45089543986389313 LCPSCPAS(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 3 LCPSCPASSPK 11 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 LCPS(0.001)CPAS(0.659)S(0.34)PK;LCPSCPAS(0.5)S(0.5)PK;LCPSCPAS(0.5)S(0.5)PK 150.09 0.00032691 92017000.0 188954.0 149086.0 143563.0 205051.0 177381.0 155527.0 173022.0 161755.0 160095.0 174109.0 True False 249037.44151264377 197275.1339643703 141659.2608176023 157779.65995636967 152754.70996893384 145801.87210382853 188420.62281197216 136759.4815101204 168557.29485957976 168013.4969046552 1.4822466414943334 1.1741624190842272 0.8431421488595735 0.9390891973750592 0.9091811835546731 0.8677985685076753 1.1214612295040656 0.8139791387576979 1.0032366325619253 1.0 17.358217607055614 -4.920036261751881 2.77339843646638 0.9344196305752002 1.5104761639660227 0.7937844316070585 0.08662913211077425 0.13262554691889314 1.7216055061541136 0.021462556973211058 0.1526047738649128 1.2021640548142123e-05 4.920036261751881 0.5760565333908225 LCPSCPAS(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LCPSCPASSPK 11 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 LCPSCPAS(0.739)S(0.261)PK;LCPSCPAS(0.896)S(0.104)PK 144.1 0.00016813 32169000.0 222588.0 199156.0 141997.0 233712.0 208422.0 208238.0 269648.0 261126.0 219714.0 212712.0 True False 260267.75208660538 218926.89150384848 145382.74700662147 220617.874344527 167583.2052698458 197317.6326979521 244104.98935753878 254271.71918586726 222926.90159194963 251275.00177273448 1.0357884797549595 0.8712641128617195 0.5785802247774444 0.8779937231641717 0.6669314658742549 0.7852656703049828 0.9714654766108385 1.0119260467296431 0.8871829669454175 1.0 17.93890762551049 -7.262404584617423 24.20711828500883 0.968637470507377 0.7928291122860531 0.31060536365795277 0.1198935644055625 69.73977840486693 1749008.650054306 0.04922795759468455 0.035382129390197914 5.4650660530788883e-08 7.262404584617423 -0.1758083582213239 LCPSCPAS(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 2 LCPSCPASSPK 11 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 LCPSCPAS(0.5)S(0.5)PK;LCPSCPAS(0.5)S(0.5)PK 144.17 0.00010454 36143000.0 145086.0 143229.0 128922.0 136673.0 137509.0 152457.0 128008.0 114020.0 139901.0 117307.0 True False 143017.04703448643 142897.36205046382 118322.53081331177 146724.3883477626 129420.99097309582 145936.7695046251 134635.62789204554 119317.78545047429 124143.87615715916 137583.3586482476 1.0394937908161614 1.038623881946379 0.8600061226577626 1.0664399371357507 0.9406732925017472 1.0607152706435539 0.9785749469618751 0.8672399527295159 0.9023175286376858 1.0 17.069946454305658 -7.597934183024852 7.303888223069019 0.9143463624732399 0.9984014538745287 0.21187232386044497 0.06634455152677285 0.3235400332399173 26.46090015438023 0.03037301284807311 0.017423948182400822 2.523863232917185e-08 7.597934183024852 0.08405509140128886 LCPSCPASS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 LCPSCPASSPK 11 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 LCPSCPAS(0.048)S(0.952)PK 126.66 0.00039959 65097000.0 46331.0 36587.0 37379.0 44443.0 39653.0 36799.0 43879.0 39101.0 36512.0 39264.0 True False 61063.29425533362 48413.03225221965 36883.33003699525 34197.35298750522 34147.8654106028 34497.9527127045 47784.14599511361 33058.83890159321 38441.94977927463 37889.37931103148 1.6116203370361113 1.2777467758128256 0.9734477235486589 0.9025577512574525 0.9012516444327358 0.9104913656545551 1.2611488196430094 0.8725093813286127 1.0145837825346027 1.0 15.20950588592467 -4.936632336310636 2.1985019372018715 0.9757957442763023 1.6746365865890307 0.7819623631484609 0.10557879991628245 0.20601224439421875 1.4961064369803492 0.0291225203892052 0.25188608681139285 1.1570913945506716e-05 4.936632336310636 0.6988408423127284 LCPSCPASS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LCPSCPASSPK 11 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 LCPSCPAS(0.013)S(0.987)PK;LCPSCPAS(0.08)S(0.919)PK 168.85 0.0003405 69624000.0 132559.0 131100.0 105327.0 165165.0 142556.0 126219.0 167394.0 162834.0 129300.0 119913.0 True False 154998.62054040778 144114.74159028364 107838.39513487194 155911.34052215493 114623.1751468087 119599.85344414934 151537.2284923896 158559.78003688413 131190.7678884325 141652.2776692145 1.0942190488624515 1.0173838639348918 0.7612895246675488 1.1006624325959524 0.8091869543705892 0.8443200166780104 1.069783211296174 1.1193591987779534 0.9261465473558312 1.0 17.11199427386311 -7.284708405562332 24.435994245351594 1.038768847330798 0.9349867287277502 0.12539498535131433 0.11638424568403771 1198.1588908617628 1258241.3880969675 0.04891400249679501 0.033001584010264366 5.191484891379912e-08 7.284708405562332 -0.10378211860304787 LCPSCPASS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 LCPSCPASSPK 11 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 LCPSCPAS(0.228)S(0.772)PK;LCPSCPAS(0.198)S(0.802)PK 186.74 0.00095858 172671000.0 219763.0 198661.0 166429.0 202924.0 201358.0 194485.0 198566.0 187177.0 185067.0 187031.0 True False 216629.13932040145 198201.01266019567 152745.85005451823 217847.7078946203 189514.51832505976 186167.32991667822 208846.7758891 195873.9267432338 164222.80561809405 219359.05914685762 0.9875550167060639 0.9035460556361297 0.6963279777392607 0.9931101489124027 0.8639466227751398 0.8486876750872732 0.9520772777808105 0.8929374857142286 0.7486483861518997 1.0 17.74293476281523 LCS(ph)PLSEPGDPSK ddPTM_PC-9_Lapatinib_30min_R1 1 LCSPLSEPGDPSK 13 0 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 LCS(0.966)PLS(0.034)EPGDPSK 94.023 0.0038726 5355600.0 26269.0 42584.0 36193.0 25695.0 48208.0 58744.0 43019.0 41258.0 45445.0 48664.0 True False 25894.39924285539 42485.39936435314 33217.35124902023 27584.696016007256 45372.50022057462 56231.65605895234 45246.31332641638 43174.99729973405 40326.505542934625 57075.507559295955 0.4536867099421517 0.744371818686236 0.5819895900971288 0.4833018083518471 0.7949557027318059 0.9852151730851113 0.7927448263059215 0.7564540228552394 0.7065465953331956 1.0 15.800584163609997 -6.368199175688571 5.932368220687028 0.8352171003449752 0.5806449417630966 0.5856047914095682 0.11274807955791105 0.1861946909241418 8.787183271052246 0.0356566823846075 0.04048060062295427 4.283520249775318e-07 6.368199175688571 -0.25457215858187865 LCS(ph)SSDTLVSEGEENQKPK ddPTM_PC-9_AZD4547_30min_R2 2 LCSSSDTLVSEGEENQKPK 19 1 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 LCS(0.726)S(0.134)S(0.134)DT(0.005)LVSEGEENQKPK;LCS(0.718)S(0.211)S(0.064)DT(0.007)LVSEGEENQKPK 132.01 1.9533e-05 73737000.0 62237.0 89931.0 76646.0 111625.0 104586.0 84600.0 114800.0 140435.0 115382.0 101805.0 True False 82027.07138998079 118999.4370534442 75629.62396039328 85891.58083905837 90066.03918576923 79309.94862618024 125016.97760293141 118733.99762525859 121480.8569629785 98240.83793703033 0.8349589957951894 1.211303156124539 0.7698389544363392 0.8742960935869919 0.9167881817488067 0.8073012231126909 1.272556100173574 1.208601230593776 1.2365616938329087 1.0 16.584035245657 -7.26468821654443 24.999715555103723 1.196813199709862 0.9098039162792857 0.5119585885495448 0.131947521504865 232.50695832721786 1789122.2070113863 0.05271670093148673 0.037211818198760946 5.4364047524410156e-08 7.26468821654443 -0.2870092834305764 LCS(ph)SSDTLVSEGEENQKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LCSSSDTLVSEGEENQKPK 19 1 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 LCS(0.945)S(0.042)S(0.01)DT(0.002)LVSEGEENQKPK;LCS(0.762)S(0.106)S(0.106)DT(0.025)LVS(0.001)EGEENQKPK 66.536 0.004624100000000001 29130300.0 29691.0 30856.0 17548.5 33045.0 47690.0 42911.0 48194.0 46472.0 40435.0 39665.0 True False 34717.09987601936 33919.17975980015 17966.92279305686 31193.5957833355 38345.4868455295 40660.6716195018 43628.71542565575 45252.15924115411 41026.28537949551 46855.95051203279 0.7409325709250926 0.723903354624928 0.38345018288430377 0.6657339237056958 0.818369629182578 0.8677803176580525 0.9311243278364767 0.9657718762856637 0.8755832488972729 1.0 15.515944655375469 -6.446542403103614 2.0993027108854956 0.9290819394072194 0.614990691623161 0.680726982967035 0.09722414936284293 0.19936135547218015 1.743128824771571 0.03668891293109715 0.041709844695561625 3.576494791373831e-07 6.446542403103614 -0.3140912477840584 LCS(ph)SSDTLVSEGEENQKPK ddPTM_PC-9_Lapatinib_30min_R1 2 LCSSSDTLVSEGEENQKPK 19 1 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 LCS(0.963)S(0.035)S(0.001)DTLVSEGEENQKPK;LCS(0.439)S(0.439)S(0.114)DT(0.009)LVSEGEENQKPK 135.26 3.6209e-05 32156000.0 97977.0 74354.0 73625.0 79836.0 110559.0 106908.0 111994.0 82903.0 109416.0 99453.0 True False 96579.8300132187 74181.83788129623 67571.83670071879 85707.4057650888 104056.1369873571 102335.79405472014 117792.50132914954 86754.97603228093 97092.41787844058 116643.31853720757 0.8279928179719193 0.6359715996731804 0.5793031058111086 0.7347819561370705 0.8920882763993435 0.8773395282137525 1.0098521098881064 0.7437629271890728 0.8323873077005218 1.0 16.83174414490246 -6.156545814821039 3.840163654666507 0.885118484597922 0.6742846428159024 0.5241897105469777 0.09295003299353308 0.19656166308517964 5.2079467322774615 0.028720111253636604 0.037872843638067914 6.973554272171619e-07 6.156545814821039 -0.21083384178201958 LCS(ph)SSSSDTSSR ddPTM_PC-9_AZD4547_30min_R2 4 LCSSSSSDTSSR 12 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 LCS(0.721)S(0.162)S(0.052)S(0.052)S(0.012)DTSS(0.001)R;LCS(0.421)S(0.421)S(0.034)S(0.118)S(0.005)DTSSR;LCS(0.998)S(0.001)SSSDTSSR;LCS(0.944)S(0.015)S(0.039)S(0.001)SDTSSR 187.78 9.510600000000001e-05 228944700.0 83944.2 82862.1 138318.3 205503.0 169276.0 125104.9 102048.8 147244.0 115166.8 112570.9 True False 110636.70945217181 109645.65336831796 136484.1089664284 158127.45833969992 145774.94931644987 117282.07082604499 111130.9455052795 124490.82313051316 121254.28193031784 108629.8270549153 1.018474506051105 1.0093512651261898 1.2564146760302952 1.4556541479142948 1.3419422019585534 1.0796488773452226 1.023024233013828 1.1460095860005348 1.1162153638431234 1.0 16.72906076023102 -6.821719115644243 18.883323484982668 1.0789754938640308 1.220383969835713 0.22920562813924816 0.1311401576289175 14.362657343170603 4497.522535982888 0.05307011289078507 0.04680377698946568 1.5075817947431682e-07 6.821719115644243 0.14140847597168227 LCS(ph)SSSSDTSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LCSSSSSDTSSR 12 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 LCS(0.943)S(0.022)S(0.034)S(0.001)SDTSSR;LCS(0.904)S(0.02)S(0.065)S(0.006)S(0.006)DTSSR;LCS(0.975)S(0.012)S(0.004)S(0.004)S(0.004)DTSSR;LCS(0.548)S(0.058)S(0.028)S(0.095)S(0.271)DTSSR;LCS(0.952)S(0.016)S(0.001)S(0.003)S(0.027)DTSSR;LCS(0.481)S(0.481)S(0.019)S(0.019)SDTSSR 158.25 5.913100000000001e-05 148604400.0 73319.8 69210.9 110711.5 112604.0 168703.0 162243.0 171106.0 167644.0 180066.0 141514.0 True False 85731.39400794049 76081.7007530968 113351.28203570191 106295.1629470935 135646.85819461866 153734.69146752177 154897.60097983674 163243.52263350054 182699.1245985966 167169.36797579232 0.5128415274044417 0.45511747561379867 0.6780625147312648 0.635853112530078 0.8114336964787806 0.9196343404838617 0.9265908153835178 0.9765157612915047 1.092898339036929 1.0 17.35095098741727 -6.213494858390326 0.6207935864026487 1.0403799919162366 0.4322813294534589 0.9429866127714435 0.04954932905906085 0.19937675936836446 0.1586299056856409 0.0328611239304906 0.06799544073572521 6.116530442683897e-07 6.213494858390326 -0.6080986624627778 LCS(ph)SSSSDTSSR ddPTM_PC-9_Lapatinib_30min_R1 5 LCSSSSSDTSSR 12 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 LCS(0.253)S(0.253)S(0.068)S(0.253)S(0.103)DT(0.068)S(0.001)SR;LCS(0.776)S(0.14)S(0.067)S(0.004)S(0.012)DTSSR;LCS(0.846)S(0.069)S(0.037)S(0.037)S(0.011)DTSSR;LCS(0.854)S(0.02)S(0.006)S(0.02)S(0.101)DTSSR;LCS(0.832)S(0.046)S(0.078)S(0.008)S(0.033)DT(0.002)SSR 187.78 0.00013868 176155500.0 78958.40000000001 83622.8 113468.3 78978.9 127425.7 153468.1 139094.9 119414.2 170239.2 109016.8 True False 77832.43873680277 83429.1765443695 104139.37437430467 84787.27177188714 119930.77085456507 146904.62711461444 146296.55332542735 124962.61967496977 151065.06859775013 127860.20862424496 0.6087307347161962 0.6525030534679543 0.8144783705175159 0.6631247726261703 0.9379835379982612 1.1489471876769506 1.1441914173264258 0.9773378365290283 1.1814861732448718 1.0 16.96420782737932 -6.43767807120944 3.0861354587978846 1.0913951070578634 0.6906195937304314 0.8545842831590789 0.07871759345898446 0.09441323142816134 1.7389723045176813 0.026222035349849678 0.0294053027271767 3.6502442774975814e-07 6.43767807120944 -0.400775513327432 LCSLFYTNEEVAK ddPTM_PC-9_Lapatinib_30min_R1 1 LCSLFYTNEEVAK 13 0 A0A0R4J2E8;A8MXP9;P43243;B3KM87;P43243-2;Q68E03 A0A0R4J2E8 MATR3;DKFZp686L22104 Matrin-3 0 84.605 0.039185000000000005 3276800.0 9456.2 7508.1 10357.0 8196.6 9889.7 9261.1 8563.1 7543.4 12298.0 10197.0 False True 9321.352853945302 7490.715455746288 9505.48743917615 8799.405307056042 9308.007289898298 8865.02434167853 9006.45541842991 7893.893902535603 10912.869736318842 11959.53786335158 0.7794074453754065 0.6263382031424972 0.7948039086279794 0.7357646597717338 0.778291552420387 0.7412514131373106 0.7530772109538614 0.660050078249712 0.9124825608654902 1.0 13.545874022000822 -8.443773940797621 4.3944104076476265 0.998255291938145 0.7351816366117628 0.7628803792238915 0.05068080111880542 0.08726729605237073 2.93049251535549 0.04668953161548858 0.012208077002471044 3.5993664082136597e-09 8.443773940797621 -0.26307365532638216 LCSSAET(ph)LESHPDIGK ddPTM_PC-9_Lapatinib_30min_R1 1 LCSSAETLESHPDIGK 16 0 O96028;O96028-3;O96028-6;O96028-5 O96028;O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 LCS(0.13)S(0.13)AET(0.727)LES(0.014)HPDIGK 89.344 0.043158999999999996 0.0 23679.0 21843.0 24200.0 21834.0 24023.0 29788.0 21702.0 21824.0 26087.0 20340.0 True False 23341.33311780323 21792.423875529912 22210.36941470145 23439.74519608884 22610.0143710352 28514.03667921955 22825.62337129847 22838.022712429014 23148.807351711625 23855.74189865361 0.978436689035464 0.9135085367753686 0.9310282408762554 0.9825619884582902 0.9477808096302082 1.195269331817714 0.9568188433740021 0.9573386067577284 0.9703662728266739 1.0 14.542048933482855 LCSSSDTLVS(ph)EGEENQKPK ddPTM_PC-9_AZD4547_30min_R2 1 LCSSSDTLVSEGEENQKPK 19 1 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 LCS(0.014)S(0.05)S(0.05)DT(0.056)LVS(0.831)EGEENQKPK 53.342 0.018565 4211400.0 5984.7 8127.2 7978.8 9957.4 9007.6 4462.7 8655.1 7789.9 5591.8 7442.0 True False 7887.710110506895 10754.158463941827 7872.995898744691 7661.875270296442 7757.050222493778 4183.646663523098 9425.387132849595 6586.149949093914 5887.371132114042 7181.45784516851 1.0983438572731485 1.4974896038938574 1.0962949401758904 1.0668969219740172 1.0801497954503083 0.5825623088963395 1.312461527458626 0.9171048679934669 0.8198016696672397 1.0 12.810061027387539 -5.737213452713027 1.7167344277391676 0.9512613344369302 1.2953256614618496 0.2979034206816864 0.19941157950961697 0.43897744217481044 2.624795374588368 0.061312460141855395 0.13368010031043073 1.8314140738701826e-06 5.737213452713027 0.3440643270249194 LCSSSDTLVS(ph)EGEENQKPK ddPTM_PC-9_Lapatinib_30min_R1 2 LCSSSDTLVSEGEENQKPK 19 1 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 LCS(0.02)S(0.019)S(0.018)DT(0.017)LVS(0.928)EGEENQKPK;LCS(0.008)S(0.03)S(0.099)DT(0.08)LVS(0.783)EGEENQKPK 80.41199999999999 0.006796300000000001 5155600.0 29006.0 22036.0 25549.6 23494.6 21577.3 17697.1 14153.2 16250.6 21006.8 17230.8 True False 28592.369120951054 21984.976995887806 23449.010512308094 25222.47125968804 20308.16563660399 16940.236286955027 14885.983443860534 17005.662201731993 18640.792972589257 20209.120821402204 1.414824987867393 1.0878739946274607 1.160318190956369 1.2480736536037982 1.0049009957472714 0.8382470685718645 0.7365972807731314 0.8414845134540623 0.9223950481234181 1.0 14.302718939555437 -6.48061181058306 2.937747634665644 0.8504626524889372 1.2130972994775715 0.7350179276344214 0.10130196003703035 0.1361969342630927 2.3489493366236442 0.03426376318340874 0.03751775386753183 3.3066497028486565e-07 6.48061181058306 0.36263464698863435 LCSSSS(ph)SDTSSR ddPTM_PC-9_AZD4547_30min_R2 1 LCSSSSSDTSSR 12 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 LCS(0.173)S(0.173)S(0.079)S(0.261)S(0.261)DT(0.052)S(0.001)SR 96.334 0.0043161 2043100.0 7922.2 7249.5 10798.0 15393.0 11113.0 10685.0 7909.8 12552.0 7110.2 10526.0 True False 10441.294808003366 9592.759103300792 10654.81146471213 11844.381669479293 9570.15177434315 10016.865260883382 8613.756876687017 10612.376816265529 7486.03065623901 10157.487943865051 1.0279406547865733 0.9444027062906488 1.0489612710933565 1.1660739087200291 0.9421770251889255 0.9861557617632613 0.8480203889279119 1.0447835995390202 0.7369962630140697 1.0 13.31025603175454 -6.640878625832809 2.498742936175282 0.9172871957569877 1.0390734810875752 0.25912855657516043 0.0963037782792232 0.40801426675547575 5.184280450890937 0.03413333688866496 0.03397914138518989 2.2862376588786061e-07 6.640878625832809 0.12178628533058755 LCYVALDFEQEMATAASS(ph)SSLEK ddPTM_PC-9_AZD4547_30min_R2 1 LCYVALDFEQEMATAASSSSLEK 23 0 P60709;A0A2R8Y793;Q6S8J3;A0A2R8YEA7;P63261;I3L4N8 P60709;P63261 ACTB;POTEE;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 LCYVALDFEQEMATAAS(0.036)S(0.735)S(0.114)S(0.114)LEK 212.41 1.568e-31 6545900.0 16999.0 14838.0 17007.0 23146.0 22201.0 19610.0 20197.0 22682.0 21257.0 18149.0 True False 22404.328398834805 19634.093327095266 16781.476067823598 17810.04730213524 19118.774367154867 18383.783599992814 21994.493873226587 19177.018080507856 22380.6016229744 17513.60903412567 1.2792525147260885 1.1210763748829715 0.9581963394937334 1.0169261668130167 1.0916524589478669 1.0496856224306246 1.2558515969135664 1.094978084936177 1.277897752505796 1.0 14.09618879051235 -7.230108185886214 24.794705256866127 1.1650967570324575 1.0790099870121304 0.09172824471617835 0.10699103851014133 1295.2329007818353 1025015.9421145216 0.04087308143951654 0.03165586083090589 5.886969884247961e-08 7.230108185886214 -0.08608677002032716 LCYVALDFEQEMATAASS(ph)SSLEK ddPTM_PC-9_Lapatinib_30min_R1 1 LCYVALDFEQEMATAASSSSLEK 23 0 P60709;A0A2R8Y793;Q6S8J3;A0A2R8YEA7;P63261;I3L4N8 P60709;P63261 ACTB;POTEE;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 LCYVALDFEQEMATAAS(0.008)S(0.453)S(0.453)S(0.087)LEK 112.06 0.00027773 0.0 487.68 970.42 633.56 739.19 541.89 1085.5 772.17 748.65 967.02 545.01 True False 480.7255937704413 968.1730521124276 581.4711424123241 793.552498465554 510.017095596731 1039.0756954240906 812.1491843431729 783.4350120811933 858.1040244279595 639.2142523198235 0.7520570638495648 1.51462995169265 0.9096654843068044 1.2414499451249863 0.7978812952711665 1.6255515136796435 1.2705429852287202 1.2256219401209638 1.3424356877427963 1.0 9.320155765628067 -6.754638358280247 24.999700925810274 1.3055388320502985 1.0729332183291211 0.19208817953124968 0.25169436177984494 282.52660885495453 1038531.870001653 0.07906172382290363 0.07737362768626113 1.7593880656432293e-07 6.754638358280247 -0.23260561372117738 LCYVALDFEQEMATAASSSSLEK ddPTM_PC-9_Lapatinib_30min_R1 2 LCYVALDFEQEMATAASSSSLEK 23 0 P60709;A0A2R8Y793;Q6S8J3;A0A2R8YEA7;P63261;I3L4N8 P60709;P63261 ACTB;POTEE;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ; 146.19 7.2871e-17 0.0 9747.37 6186.1 8688.5 8167.570000000001 7249.41 11930.5 9680.5 7472.16 8944.1 8069.58 False True 9608.370716351268 6171.776465522854 7974.165068579892 8768.240344014805 6823.013956688438 11420.260326353853 10181.708922949718 7819.343832061192 7936.721272451573 9464.39615096053 1.0152122294010406 0.6521046210535564 0.8425434588101643 0.9264447730376254 0.7209138172006863 1.2066549354228822 1.0757906537879216 0.8261851794176659 0.8385871793464694 1.0 13.208294746448926 -6.728260103984345 24.999825526045694 0.9839774824376564 0.8273750346194266 0.24492081152036072 0.1384521755501176 298.12932260831565 224632.89361337648 0.04726692342183646 0.04726393180507235 1.8695621026477423e-07 6.728260103984345 -0.15660244781822974 LDADYPLR ddPTM_PC-9_Lapatinib_30min_R1 1 LDADYPLR 8 0 F8VVL1;O43583 F8VVL1 DENR Density-regulated protein 0 96.492 0.028120999999999997 1892500.0 36601.0 31587.0 40183.0 31082.0 33189.0 42625.0 34795.0 28798.0 41552.0 27945.0 False True 36079.06302819863 31513.862242199477 36879.30885086562 33367.87396651246 31236.88827208457 40802.02811372812 36596.51484675745 30136.060212267697 36871.97619804203 32775.25601562809 1.1008018674513236 0.9615138391954239 1.1252180252468695 1.0180812607719005 0.9530631357140281 1.2449034141570903 1.1165897477446791 0.9194759668055086 1.124994299982295 1.0 15.00031942928815 -4.459851363200291 15.846983575247496 1.0538575957282974 1.5686324023283247 0.022806844068973597 0.09566215123193363 2426236.592383213 14338268.87670525 0.023658100724846687 40446509.300356664 3.468555410607097e-05 4.459851363200291 0.5147748066000273 LDAQSLNLSQEDFDRYMSGQT(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 2 LDAQSLNLSQEDFDRYMSGQTSPR 24 1 E9PFK9;Q9UJ41;Q9UJ41-4;Q9UJ41-3;A0A0A0MSJ3;Q3HKR1 E9PFK9 RABGEF1 Rab5 GDP/GTP exchange factor 1 LDAQSLNLSQEDFDRY(0.025)MS(0.126)GQT(0.424)S(0.424)PR;LDAQS(0.001)LNLS(0.002)QEDFDRY(0.242)MS(0.091)GQT(0.332)S(0.332)PR 70.699 0.00045231 54581000.0 41204.0 22891.4 51890.0 76755.0 58547.0 41310.0 42233.0 53793.0 33549.0 52458.0 True False 54306.01490355844 30290.59738427476 51201.90469567629 59060.320602928805 50418.75964478252 38726.87916959221 45991.655183838106 45480.52789016664 35322.33164835904 50621.4613869725 1.0727863916930334 0.5983746133427528 1.0114663483194732 1.166705167822912 0.9959957350768592 0.7650288653965771 0.9085406450884115 0.8984435977162665 0.6977738429623702 1.0 15.627461536648482 -6.743809019691603 24.977981110176664 0.8510215475823772 0.9618072833966484 0.1165969149310172 0.15768614135835468 614.3262677699523 870351.0020939555 0.05396887810862624 0.053854980802241055 1.803810789404564e-07 6.743809019691603 0.1107857358142712 LDAQSLNLSQEDFDRYMSGQT(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LDAQSLNLSQEDFDRYMSGQTSPR 24 1 E9PFK9;Q9UJ41;Q9UJ41-4;Q9UJ41-3;A0A0A0MSJ3;Q3HKR1 E9PFK9 RABGEF1 Rab5 GDP/GTP exchange factor 1 LDAQSLNLSQEDFDRY(0.022)MS(0.107)GQT(0.435)S(0.435)PR;LDAQSLNLSQEDFDRY(0.177)MS(0.205)GQT(0.339)S(0.278)PR 64.16 0.0009406000000000001 25218800.0 21534.2 14824.3 21097.2 25961.0 35054.0 37042.0 28060.2 36123.9 33758.3 22439.0 True False 25179.514740162864 16295.958533614375 21600.237259576563 24506.489336697603 28185.42033724451 35099.45231128581 25402.134717744622 35175.68590143583 34251.951273070954 26507.013072973725 0.9499189769456007 0.614779133686306 0.8148876374758324 0.9245285113502345 1.0633193660730516 1.324157203780642 0.9583175081934967 1.3270331819204704 1.292184493921493 1.0 14.69408648967954 -6.1777313559197395 1.8326059761540459 1.188014636401262 0.7740596318203488 0.5899407458212995 0.1412814750521296 0.22767176609817957 1.5088091660594367 0.04720327628574039 0.06644054866181946 6.641537728510837e-07 6.1777313559197395 -0.4139550045809133 LDAQSLNLSQEDFDRYMSGQT(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 LDAQSLNLSQEDFDRYMSGQTSPR 24 1 E9PFK9;Q9UJ41;Q9UJ41-4;Q9UJ41-3;A0A0A0MSJ3;Q3HKR1 E9PFK9 RABGEF1 Rab5 GDP/GTP exchange factor 1 LDAQSLNLSQEDFDRY(0.037)MS(0.165)GQT(0.399)S(0.399)PR 69.27 0.00055905 17978000.0 49667.0 27031.0 42644.0 34895.0 28636.0 35917.0 23104.0 16849.0 38386.0 21087.0 True False 48958.73947218773 26968.411380279693 39137.97493060033 37461.29470630759 26951.686780542146 34380.913636616366 24300.21207125977 17631.866050298573 34062.56445750002 24731.859853338687 1.9795817929794117 1.0904319990572438 1.5824921846836717 1.5146978402940647 1.0897557620157625 1.3901467111853743 0.9825468935761964 0.71292115331627 1.377274683727505 1.0 14.594083115043441 -6.421097160508828 0.7462937755560911 0.9967963810495438 1.5875961819019566 0.4019999869758426 0.26983092064081626 0.7436792325675534 0.9159657033072338 0.1635780789673482 0.2373761191173757 3.7923013398835854e-07 6.421097160508828 0.5907998008524128 LDAQSLNLSQEDFDRYMSGQTS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 LDAQSLNLSQEDFDRYMSGQTSPR 24 1 E9PFK9;Q9UJ41;Q9UJ41-4;Q9UJ41-3;A0A0A0MSJ3;Q3HKR1 E9PFK9 RABGEF1 Rab5 GDP/GTP exchange factor 1 LDAQSLNLS(0.001)QEDFDRY(0.026)MS(0.103)GQT(0.396)S(0.475)PR 49.888000000000005 0.014147 4580500.0 10498.0 6184.9 9600.0 8466.8 5492.5 7313.6 5176.3 5073.4 7669.4 6484.6 True False 10348.296594902575 6170.579244049122 8810.725057071648 9089.476716416826 5169.441948670477 7000.814376834292 5444.303486169584 5309.128685357284 6805.591409637641 7605.454469813634 1.360641449630051 0.8113360310735418 1.1584744990640312 1.195126044405806 0.679701912514 0.920499150263908 0.7158419668118785 0.6980685646636157 0.8948303400736033 1.0 12.892818744545613 -6.257041735378374 24.998753266519074 0.8030617723032262 1.1104674783800934 0.47542596631936496 0.16012014820308357 334.11339437583683 1899292.2586480181 0.04594560267423095 0.05724416610303112 5.532969352346986e-07 6.257041735378374 0.30740570607686724 LDDCGLTEAR ddPTM_PC-9_Lapatinib_30min_R1 2 LDDCGLTEAR 10 0 P13489;E9PMA9;E9PMN0;E9PIK5;E9PMJ3;E9PLZ3;E9PIM9 P13489 RNH1 Ribonuclease inhibitor 0 ; 138.06 0.00054583 8525200.0 36559.0 37438.0 53017.0 36203.0 44035.0 48925.0 43267.0 37647.0 46677.0 32259.0 False True 36037.66195590051 37351.31461118387 48658.146911538264 38865.48938966765 41444.947876141 46832.59179974541 45507.1535529431 39396.21705713046 41419.74472939947 37834.92516758442 0.9524972441805241 0.9872178799281758 1.28606430952391 1.0272384369076586 1.0954150878471807 1.2378137816397707 1.2027816455662494 1.0412658907776484 1.094748953405791 1.0 15.207430971224836 -5.030187080982192 24.256816764638465 1.127792735506419 0.9611773056374753 0.32478076453843696 0.08883830846588273 435.65493346070775 350071.9737224822 0.022355457449499065 0.059360576956209554 9.32852369529258e-06 5.030187080982192 -0.16661542986894373 LDDGHLNNSLS(ph)SPVQADVYFPR ddPTM_PC-9_Lapatinib_30min_R1 1 LDDGHLNNSLSSPVQADVYFPR 22 0 F8WF17;B9A055;U3KQ88;Q3ZCW2 F8WF17 LGALSL Galectin;Galectin-related protein 1 LDDGHLNNS(0.001)LS(0.833)S(0.166)PVQADVYFPR 143.25 1.083e-06 3091000.0 12900.0 11053.0 12639.0 10225.0 16906.0 16626.0 13737.0 14325.0 19109.0 12592.0 True False 12716.043634429732 11027.407457594296 11599.870207950895 10976.98060960008 15911.622318474845 15914.944737098958 14448.234644342789 14990.591795983568 16956.743193309227 14768.510422214675 0.8610241162373669 0.7466837983204425 0.7854461876197387 0.7432693139511615 1.077401976474263 1.0776269428743352 0.9783136031518703 1.0150374931133772 1.1481688205875542 1.0 13.85023670024548 -6.262598587835802 24.999998929577295 1.0480312339476983 0.781528580956034 0.8533159528771167 0.05388417741632499 37.4051682099471 806695.2065809077 0.016334321375901774 0.01958225217552337 5.462625304524725e-07 6.262598587835802 -0.2665026529916643 LDDGHLNNSLSS(ph)PVQADVYFPR ddPTM_PC-9_AZD4547_30min_R2 2 LDDGHLNNSLSSPVQADVYFPR 22 0 F8WF17;B9A055;U3KQ88;Q3ZCW2 F8WF17 LGALSL Galectin;Galectin-related protein 1 LDDGHLNNSLS(0.247)S(0.753)PVQADVYFPR;LDDGHLNNSLS(0.245)S(0.755)PVQADVYFPR 183.1 4.5183e-15 20695000.0 34040.0 27103.0 44881.0 67467.0 61061.0 54740.0 37852.0 64328.0 43005.0 43816.0 True False 44864.01192401534 35863.514721947926 44285.848615275565 51913.52550475921 52583.73413958127 51317.0991465378 41220.754670959686 54387.58571038312 45278.15650355243 42282.01517655246 1.0610660758878574 0.8481978584085104 1.047392098753002 1.227792130720106 1.243643045867446 1.213686219359662 0.9749004274947308 1.2863054299394847 1.0708608923791667 1.0 15.367756517290303 -5.534537411581295 6.4286159224705415 1.1562107887351358 0.9522508954951985 0.3270188641591243 0.10966905164579838 0.14135122707216882 25.287098518516796 0.028499988043439478 0.0521730470506632 2.920536164603414e-06 5.534537411581295 -0.20395989323993735 LDDGHLNNSLSS(ph)PVQADVYFPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LDDGHLNNSLSSPVQADVYFPR 22 0 F8WF17;B9A055;U3KQ88;Q3ZCW2 F8WF17 LGALSL Galectin;Galectin-related protein 1 LDDGHLNNSLS(0.173)S(0.827)PVQADVYFPR;LDDGHLNNSLS(0.17)S(0.83)PVQADVYFPR 156.79 3.3082999999999997e-06 5768800.0 16694.0 17877.9 21845.5 24364.0 22803.3 25066.7 28605.8 25213.5 29434.3 17673.1 True False 19519.96447847049 19652.69976107504 22366.37956952011 22998.964069153757 18335.15705985872 23752.15812459661 25896.05153594269 24551.672340911482 29864.72095327527 20877.093129817382 0.9349943671320509 0.9413523060356702 1.0713359101500428 1.1016363210214284 0.878242815982452 1.1377138558946678 1.2404050398643411 1.1760100981609332 1.4305018791443456 1.0 14.349633228471372 -6.965339075886525 5.953161650335277 1.2219322161767023 0.9943753500153973 0.46485417907120874 0.11514916832782486 0.15825963443530194 15.594822872625732 0.040248348717857096 0.03491746672140196 1.0830809671905152e-07 6.965339075886525 -0.227556866161305 LDDGHLNNSLSS(ph)PVQADVYFPR ddPTM_PC-9_Lapatinib_30min_R1 3 LDDGHLNNSLSSPVQADVYFPR 22 0 F8WF17;B9A055;U3KQ88;Q3ZCW2 F8WF17 LGALSL Galectin;Galectin-related protein 1 LDDGHLNNSLS(0.248)S(0.752)PVQADVYFPR;LDDGHLNNS(0.001)LS(0.221)S(0.778)PVQADVYFPR;LDDGHLNNSLS(0.042)S(0.958)PVQADVYFPR 194.9 1.9205e-19 19691600.0 36370.7 31493.5 37074.8 29540.7 52151.0 53215.0 52480.4 43031.0 54567.0 45432.4 True False 35852.047148430494 31420.57873570486 34026.653056866664 31713.221622886398 49083.58071281088 50939.118500223856 55197.57832343065 45030.37735238874 48421.08984401613 53285.329805132315 0.6728314768725953 0.5896665902343445 0.6385745041140629 0.5951585875298806 0.9211462309103183 0.9559689071365666 1.0358869603564724 0.8450802034456306 0.9087133366931386 1.0 15.701450773123499 -6.281639446205968 7.212082025165148 0.9425451114331448 0.6223978545102379 0.898377796221994 0.052793728212776045 0.054760297981659184 13.961053836945377 0.0166269041001305 0.019408173339532136 5.228300654190489e-07 6.281639446205968 -0.3201472569229069 LDDLFLK ddPTM_PC-9_Lapatinib_30min_R1 1 LDDLFLK 7 0 P42704 P42704 LRPPRC Leucine-rich PPR motif-containing protein, mitochondrial 0 92.925 0.024582 0.0 9471.3 8639.6 8098.4 9463.7 7550.8 6069.3 7321.5 8957.5 10401.0 7475.6 False True 9336.2375251763 8619.595537015444 7432.580812728018 10159.692067977729 7106.676789443975 5809.730187229323 7700.5714456253645 9373.698150961462 9229.529852614432 8767.74749938913 1.0648387771005927 0.9831026198708382 0.8477183921236171 1.1587573739647017 0.8105476109957677 0.6626251711325059 0.8782838974505005 1.0691113255274003 1.0526682997266374 1.0 13.097990535672148 -10.771981466012576 8.427947954725328 1.0000000277027037 0.9409737292573976 0.010331438809127569 0.14161832335703975 7.869497731268835e-08 6.99026283106215e-09 0.14643040919310335 0.03551457441251799 1.6905130745804105e-11 10.771981466012576 -0.05902629844530605 LDDQES(ph)PVYAAQQR ddPTM_PC-9_AZD4547_30min_R2 2 LDDQESPVYAAQQR 14 0 Q96ST3;H3BMA2;H3BT34;H3BQ76;H3BQ88;H3BNA0;H3BNZ3;H3BQL7;H3BP90 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 LDDQES(1)PVYAAQQR;LDDQES(1)PVYAAQQR 184.22 6.7348e-06 9869800.0 63000.0 63931.0 62496.0 90461.0 73039.0 66043.0 59601.0 84816.0 62154.0 64998.0 True False 83032.68951859485 84595.44551115572 61667.262205838975 69606.61405851787 62898.79559491123 61913.32076972593 64905.37353756389 71709.6360777865 65439.3335500941 62722.439803851456 1.3238115382350968 1.3487269592143825 0.9831770319950518 1.1097561618488523 1.0028116857636802 0.9871000070045769 1.034803074315014 1.1432851831344608 1.0433161362143923 1.0 15.936694058652717 -5.255846241746867 24.999250128741604 1.0425179963968048 1.3362692863537344 0.8503218566189226 0.05002242296457103 159.3217502380885 712103.3299399425 0.0131585876091733 0.032822164579754357 5.548221082199425e-06 5.255846241746867 0.2937512899569297 LDDQES(ph)PVYAAQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LDDQESPVYAAQQR 14 0 Q96ST3;H3BMA2;H3BT34;H3BQ76;H3BQ88;H3BNA0;H3BNZ3;H3BQL7;H3BP90 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 LDDQES(0.999)PVY(0.001)AAQQR 74.96600000000001 0.018036 3252400.0 16155.0 20160.0 22006.0 18119.0 22083.0 19227.0 22412.0 14336.0 16901.0 16273.0 True False 18889.722424205727 22161.351567201556 22530.706498219733 17103.851172590585 17755.994674141893 18218.702272800947 20288.973111171425 13959.69519024757 17148.145151449327 19223.16608300289 0.9826540717924717 1.152846074965591 1.172060127917293 0.8897520366176204 0.9236769113617415 0.9477472230191005 1.0554438859637654 0.7261912595444266 0.8920562345144438 1.0 14.230558349171723 -5.768638508059367 24.999999946848302 0.9149025607520753 1.1075526976054062 0.4477342320388932 0.09312789975059667 142.68350851676794 495490.5993122952 0.026701228065052304 0.04054277076507773 1.703575917004704e-06 5.768638508059367 0.19265013685333088 LDDQES(ph)PVYAAQQR ddPTM_PC-9_Lapatinib_30min_R1 1 LDDQESPVYAAQQR 14 0 Q96ST3;H3BMA2;H3BT34;H3BQ76;H3BQ88;H3BNA0;H3BNZ3;H3BQL7;H3BP90 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 LDDQES(0.981)PVY(0.019)AAQQR 85.988 0.0066782 5171200.0 18046.0 22117.0 28674.0 22459.0 22812.0 28567.0 30299.0 22098.0 25563.0 20073.0 True False 17788.66073076891 22065.789445364433 26316.53440484088 24110.70978102772 21470.24301011759 27345.256002929513 31867.7339658544 23124.753752715184 22683.825749676256 23542.591304408757 0.7555948493842168 0.9372710573806815 1.1178265835126082 1.0241315184583173 0.9119745032526183 1.1615227758640418 1.3536204895119857 0.9822518453346584 0.9635228958601646 1.0 14.522985504355221 -4.895873513660977 2.5495784718740464 1.070585849519362 0.7263570785633879 0.38909111056706736 0.11965239211938399 0.4256459109023188 4.320171038650682 0.033734753647599425 0.28838581433827 1.270944208166491e-05 4.895873513660977 -0.34422877095597415 LDEEEEDNEGGEWER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LDEEEEDNEGGEWER 15 0 Q99613-2;Q99613 Q99613-2 EIF3C Eukaryotic translation initiation factor 3 subunit C 0 134.21 8.013e-05 0.0 1554.5 4021.7 3595.2 1649.9 3579.2 5004.7 4045.3 3569.5 1032.4 1114.5 False True 1817.646147225491 4420.947797510637 3680.9232028719257 1557.4614520479718 2877.881453502183 4742.244721729177 3662.0998985642404 3475.8044071978725 1047.496896891089 1316.550027622855 1.380613048565582 3.357979343552209 2.7958855536376017 1.1829869122862755 2.185926393316361 3.6020239430564676 2.7815881065883072 2.640085324728403 0.7956377463167391 1.0 10.362546628098551 LDEEEEDNEGGEWER ddPTM_PC-9_Lapatinib_30min_R1 1 LDEEEEDNEGGEWER 15 0 Q99613-2;Q99613 Q99613-2 EIF3C Eukaryotic translation initiation factor 3 subunit C 0 187.57 5.441199999999999e-38 0.0 5797.7 6206.4 5518.1 6677.4 8998.2 8475.3 5634.3 6632.1 6592.8 3469.3 False True 5715.023734832031 6192.029462120077 5064.423118481986 7168.47827115341 8468.94356714186 8112.831175889265 5926.016485158372 6940.251577671389 5850.249438738242 4068.9638824483263 1.404540295745574 1.5217705639584804 1.244646859690159 1.761745367678241 2.081351373914391 1.9938321917489503 1.4563944670830165 1.705655734033055 1.4377737448035794 1.0 11.99044575926296 -5.772296739517031 24.990992360211635 1.6894788710135855 1.4034643558623952 0.1037373458547537 0.2973154409567314 381.6417685720507 878446.5159079228 0.08389098259429918 0.12581703310585768 1.6892863019740288e-06 5.772296739517031 -0.28601451515119036 LDEGT(ph)PPEPK ddPTM_PC-9_AZD4547_30min_R2 4 LDEGTPPEPK 10 0 A0A1B0GVU7;H0YN01;H0YMT1;Q9Y4G6 A0A1B0GVU7;Q9Y4G6 TLN2 Talin-2 1 LDEGT(1)PPEPK;LDEGT(1)PPEPK;LDEGT(1)PPEPK;LDEGT(1)PPEPK 114.76 0.0028863000000000005 82104200.0 449860.0 417940.0 514547.0 532983.0 489831.0 604924.0 572351.0 647383.0 549156.0 556164.0 True False 592906.1223307155 553030.931737849 507723.77058096265 410112.0038552646 421826.42074851727 567098.0066518127 623289.1302091964 547344.8327313912 578183.2650358063 536692.8676431457 1.1047400814816617 1.0304421114565039 0.946022951284225 0.7641465511853113 0.7859735915644687 1.0566527726410624 1.1613516180051597 1.019847413167652 1.0773075252049895 1.0 19.033737190041293 -6.961475032091473 24.04577509000354 1.072383726190934 0.9238604719976169 0.30707476822460633 0.10248345249849604 142.3932719869485 88875.57276552 0.04027318545741784 0.0355175081454799 1.0927604489833312e-07 6.961475032091473 -0.14852325419331702 LDEGT(ph)PPEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LDEGTPPEPK 10 0 A0A1B0GVU7;H0YN01;H0YMT1;Q9Y4G6 A0A1B0GVU7;Q9Y4G6 TLN2 Talin-2 1 LDEGT(1)PPEPK;LDEGT(1)PPEPK;LDEGT(1)PPEPK 116.84 0.0024625 48116800.0 420048.0 495780.0 420136.0 523499.0 570923.0 413861.0 521397.0 404791.0 412031.0 340693.0 True False 491153.830073834 544997.7619041265 430153.63561465254 494169.0482366563 459054.73655504663 392157.40059934853 472006.5015726154 394165.66516151663 418056.1738889311 402457.94397569506 1.2203854773543628 1.3541732001121578 1.068816362190207 1.2278774854211842 1.140627843049284 0.9744059136351186 1.1728095037953095 0.9793959121982713 1.0387574158908341 1.0 18.61847850688705 -5.6609372805694465 0.409181997473509 1.001175927349885 1.3705127125586731 0.5336595319577728 0.08203276362478922 2.107645669813017 0.4678555252944131 0.07105034168017474 0.3569528809135733 2.183045157531365e-06 5.6609372805694465 0.3693367852087881 LDEGT(ph)PPEPK ddPTM_PC-9_Lapatinib_30min_R1 4 LDEGTPPEPK 10 0 A0A1B0GVU7;H0YN01;H0YMT1;Q9Y4G6 A0A1B0GVU7;Q9Y4G6 TLN2 Talin-2 1 LDEGT(1)PPEPK;LDEGT(1)PPEPK;LDEGT(1)PPEPK;LDEGT(1)PPEPK 103.44 0.0069188999999999995 89857500.0 176142.0 234604.0 223009.0 207422.0 218647.0 231268.0 201998.0 187585.0 235070.0 192330.0 True False 173630.1827795132 234060.78885202686 204674.0608596349 222676.5058195074 205786.61333654157 221377.20675203938 212456.46805619512 196300.88391271097 208593.94120316082 225573.98423638445 0.7697260983676288 1.0376231534162597 0.9073478111959576 0.987155086049991 0.9122799068925111 0.9813951174442742 0.9418482755243479 0.8702283846128396 0.9247251712527725 1.0 17.78324116372748 -2.0548825936918895 5.074361980586638 0.9343017954534819 0.8978715015636066 0.0 0.07249380137546173 0.0 0.0 0.015224939566120654 0.0 0.008812870862089452 2.0548825936918895 -0.03643029388987529 LDFCSALSSQGSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 LDFCSALSSQGSSPR 15 0 K7EN08;Q14938-6;Q14938-5;Q14938-3;Q14938-4;Q14938 K7EN08 NFIX Nuclear factor 1;Nuclear factor 1 X-type 1 LDFCSALSS(0.055)QGS(0.319)S(0.626)PR 82.57799999999999 0.039352 0.0 7303.4 7916.9 11387.0 13058.0 12249.0 8157.0 13524.0 12231.0 10000.0 7805.4 True False 9625.72927984294 10475.883101582458 11236.000939866377 10047.679844088912 10548.437783130488 7646.941500517152 14727.609800540493 10340.97999041934 10528.579584595376 7532.13532177886 1.2779549050334424 1.3908251317912295 1.4917417783743132 1.3339749506406846 1.4004578160764203 1.0152421821745998 1.9553033995494231 1.3729147909117911 1.3978213527513799 1.0 12.878843204198077 -4.7636518749365315 6.880000691660688 1.3953200340889533 1.2753893965617973 0.005928884058706396 0.25058264144389336 0.6258329579977301 164.4310080127632 0.05976960797025165 0.35322893219797563 1.7232493567877704e-05 4.7636518749365315 -0.11993063752715605 LDFGPIT(ph)PGT(ph)SSAPTT(ph)T(ph)T(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LDFGPITPGTSSAPTTTTK 19 0 H0Y897;H7C556;D3YTG3;Q7Z7G0-4;H0YF57;H7C4T1;H0YEL2;H0YDN0;Q5JPC9 H0Y897 ABI3BP;DKFZp667H216 Target of Nesh-SH3 5 LDFGPIT(0.802)PGT(0.664)S(0.257)S(0.276)APT(0.395)T(0.873)T(0.873)T(0.86)K 53.747 0.03259 0.0 1524.7 1676.7 3236.0 1613.6 2936.6 2971.6 1694.9 1849.9 1899.4 875.84 True False 1782.8015958023198 1843.151695075735 3313.15851259834 1523.195223361783 2361.194310559486 2815.764064797173 1534.3468019866352 1801.3420851310668 1927.1751316882355 1034.6228588543747 1.7231415104982257 1.7814720400790627 3.202286209167039 1.4722226658015256 2.2821787575561667 2.7215366843093283 1.4830010654177879 1.7410615566001229 1.86268369695811 1.0 10.01488925642903 -8.647807621154943 0.64147865408454 1.0081840781188185 2.168586948442303 0.2949455390397606 0.5140930412847257 1.2215358804171337 1.1154544728045828 0.5362176055585712 0.2145067788334626 2.2500510872313957e-09 8.647807621154943 1.1604028703234843 LDFIES(ph)DSPCSSEALSK ddPTM_PC-9_Lapatinib_30min_R1 1 LDFIESDSPCSSEALSK 17 0 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3;O43432-4 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 LDFIES(0.514)DS(0.43)PCS(0.027)S(0.027)EALS(0.001)K 73.208 0.010975 1463500.0 2806.2 4805.7 6241.5 5235.9 7539.6 4702.1 6999.1 5583.8 7766.1 5259.7 True False 2766.1830734059445 4794.572696911329 5728.347962886736 5620.965552450376 7096.135551423922 4501.00214413046 7361.479151140679 5843.2437326640875 6891.400037341506 6168.832136890286 0.4484127646891004 0.7772253467944547 0.9285952082616405 0.9111879570910013 1.1503207404507347 0.7296360225485757 1.193334327760069 0.9472204143343204 1.1171320412708565 1.0 12.590781673583972 -4.585801702638601 1.0656941369811466 1.0117995480822903 7.456197421668618e-17 0.6580304540148709 0.12445403865761863 1.4695344467762599 1.041685175649899 0.03701666925338152 1.8605580086941322 2.5953641259202755e-05 4.585801702638601 -1.0117995480822903 LDFIESDS(ph)PCSSEALSK ddPTM_PC-9_AZD4547_30min_R2 1 LDFIESDSPCSSEALSK 17 0 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3;O43432-4 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 LDFIES(0.024)DS(0.969)PCS(0.003)S(0.003)EALSK 146.3 1.4252000000000002e-11 0.0 6665.3 7017.8 9106.0 9793.0 10458.0 9829.5 7703.2 11635.0 7547.6 7770.6 True False 8784.726753147457 9286.16660944125 8985.248490245294 7535.37515034176 9006.087218220157 9214.859811123377 8388.769876924249 9837.078095701829 7946.550727269206 7498.553659186565 1.1715228232560804 1.2383943666342456 1.1982642118240179 1.0049104791175407 1.201043244811177 1.2288849596794105 1.1187183899987259 1.3118633996371167 1.0597444638585463 1.0 12.87239663627817 -8.509545995982808 22.975742029137308 0.9999999768717679 1.1807071811836347 0.40524504315593013 0.07642258257815245 202.07576748863053 348227.365628603 0.07326705200686856 0.01891747147432108 3.0935276636246927e-09 8.509545995982808 0.18070720431186682 LDFIESDS(ph)PCSSEALSK ddPTM_PC-9_Lapatinib_30min_R1 1 LDFIESDSPCSSEALSK 17 0 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3;O43432-4 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 LDFIES(0.032)DS(0.966)PCS(0.002)S(0.001)EALSK 139.29 8.2766e-08 0.0 3679.2 5010.2 5508.2 4566.2 5037.1 5386.1 4696.1 5372.8 6164.3 4298.1 True False 3626.7339333173545 4998.599189725769 5055.337058266876 4902.013580396663 4740.827681319626 5155.749058612338 4939.24107980623 5622.439902370719 5470.011621043282 5041.020858141747 0.7194443418062475 0.9915847068263042 1.0028399406644006 0.9724247763187542 0.9404499236821686 1.0227589219920192 0.9798096891086787 1.1153375597107325 1.085099977757218 1.0 12.299500208435154 -4.758428650336814 4.511828174507158 1.0129850104087743 0.6939233262230946 0.7633974423756158 0.04904600371795405 0.11048804812920106 4.956580910497468 0.013606443295074695 0.11538338353014438 1.744099869779252e-05 4.758428650336814 -0.3190616841856797 LDFLPEMMVDHCS(ph)LNSSPVSK ddPTM_PC-9_AZD4547_30min_R2 1 LDFLPEMMVDHCSLNSSPVSK 21 0 F5H3J7;F5H0D8;E9PKU1;Q92879-4;G5EA30 F5H3J7 CELF1 1 LDFLPEMMVDHCS(0.328)LNS(0.328)S(0.328)PVS(0.017)K 47.088 0.043907 3878400.0 5930.5 6759.2 16775.0 41556.0 26535.0 18606.0 10336.0 28323.0 11238.0 18226.0 True False 7816.275637936924 8943.979216639866 16552.552539409713 31975.90623379986 22851.07327744042 17442.56387870811 11255.883976514822 23946.33114779226 11832.017737168295 17587.913287562653 0.4444117679079205 0.50852986766569 0.9411322576348441 1.8180613988136796 1.299248688791275 0.9917358354866733 0.639978364259645 1.3615220155040213 0.6727357329840455 1.0 14.102296704413481 -5.324263628789173 4.08501439818826 1.125552222436651 0.467589498893063 0.3701989920663098 0.32426450996395145 0.22520575844852103 7.510025314232355 0.09039073325471167 0.2108925486988221 4.7395419458648335e-06 5.324263628789173 -0.657962723543588 LDFLPEMMVDHCSLNS(ph)SPVSK ddPTM_PC-9_AZD4547_30min_R2 2 LDFLPEMMVDHCSLNSSPVSK 21 0 F5H3J7;F5H0D8;E9PKU1;Q92879-4;G5EA30 F5H3J7 CELF1 1 LDFLPEMMVDHCS(0.079)LNS(0.449)S(0.449)PVS(0.024)K;LDFLPEMMVDHCS(0.11)LNS(0.401)S(0.401)PVS(0.088)K 64.589 0.0031731 17894600.0 11614.6 10009.2 36652.0 117587.0 73061.0 60989.0 28158.7 69974.0 32846.2 49465.0 True False 15307.801201312233 13244.478159425937 36165.97053200863 90479.13385104008 62917.74127465892 57175.3481886773 30664.769749369974 59161.126142556124 34582.383075153666 47733.24540597422 0.3206947499822908 0.2774686289771589 0.7576683760849445 1.895516072320443 1.3181115329481499 1.1978097802149719 0.6424195440424006 1.2394113502944764 0.72449260009514 1.0 15.542706808793765 -5.522715396684679 24.99999958098267 1.1578546089831903 0.3537032524426496 0.518041534424114 0.3260935337414907 4.472905819290589 684558.1341254507 0.09322685995506012 0.16371665026641974 3.001128584354526e-06 5.522715396684679 -0.8041513565405407 LDFLPEMMVDHCSLNS(ph)SPVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LDFLPEMMVDHCSLNSSPVSK 21 0 F5H3J7;F5H0D8;E9PKU1;Q92879-4;G5EA30 F5H3J7 CELF1 1 LDFLPEMMVDHCS(0.15)LNS(0.448)S(0.362)PVS(0.039)K 44.625 0.040021 6509000.0 5519.2 8997.1 13238.0 16824.0 23976.0 27860.0 18702.0 17717.0 20920.0 14292.0 True False 6453.491550831091 9890.272628237548 13553.644125394569 15881.40582414393 19278.074913156117 26398.972555273005 16930.41116924541 17251.947522713188 21225.91542324833 16883.026464590243 0.38224731592800476 0.585811593021014 0.8027970668541815 0.9406729212592855 1.1418613217001792 1.5636398255159472 1.0028066475376645 1.0218515950855556 1.257234031337135 1.0 14.043285925424067 -5.493371162931527 1.2098302824481388 1.1735689067614012 0.38372548433147646 0.7373380310167743 0.16133619806364338 0.32052091596328214 0.8135447399636959 0.05692466492610214 0.23232969681228458 3.210915207624127e-06 5.493371162931527 -0.7898434224299248 down LDFLPEMMVDHCSLNSS(ph)PVSK ddPTM_PC-9_AZD4547_30min_R2 1 LDFLPEMMVDHCSLNSSPVSK 21 0 F5H3J7;F5H0D8;E9PKU1;Q92879-4;G5EA30 F5H3J7 CELF1 1 LDFLPEMMVDHCS(0.023)LNS(0.358)S(0.56)PVS(0.059)K 61.437 0.0059405000000000005 3177200.0 7170.2 8683.5 30009.0 82350.0 51605.0 38428.0 19965.0 51345.0 22371.0 37620.0 True False 9450.174450575054 11490.271559902403 29611.06105246771 63365.47979481704 44440.5365171401 36025.09108518735 21741.84632267014 43410.81004072287 23553.48538869831 36302.935250636816 0.2603143350621843 0.31651081325995106 0.8156657539681528 1.745464364171641 1.224158217794814 0.9923465096270806 0.5989005068753703 1.1957933908377663 0.6488038839307118 1.0 15.147798580672323 -5.348535716160459 3.914403033950088 1.0635707749616088 0.2812514833629688 0.49702333811032573 0.3035841484220052 0.187293988229879 5.261835078505063 0.08573617192920269 0.19827102331662144 4.481921893799876e-06 5.348535716160459 -0.78231929159864 LDFVS(ph)LQQENSR ddPTM_PC-9_AZD4547_30min_R2 1 LDFVSLQQENSR 12 0 Q03001-3 Q03001-3 DST Dystonin 1 LDFVS(0.999)LQQENS(0.001)R 72.87899999999999 0.023983 10528000.0 11202.0 8655.9 10633.0 15512.0 14152.0 10834.0 10206.0 12041.0 10676.0 12881.0 True False 14764.00298392538 11453.750399649818 10491.999472521224 11935.948058010963 12187.239081301548 10156.548267329028 11114.314228358202 10180.34012465369 11240.311564514033 12430.04011067126 1.1877679277358406 0.9214572356702783 0.84408412033311 0.960250164258431 0.9804665932524815 0.8170969825438917 0.8941495063090343 0.8190110437305678 0.9042860251805754 1.0 13.601543331400277 -4.764492335513592 4.74812423700884 0.8965549845549177 1.208387789371863 0.661505199121321 0.060795289392307765 0.1085787875120869 5.895428690295924 0.015129350221128742 0.11418165189539593 1.7199176943051576e-05 4.764492335513592 0.3118328048169454 LDGLVET(ph)PTGYIESLPR ddPTM_PC-9_AZD4547_30min_R2 5 LDGLVETPTGYIESLPR 17 0 P55209;F8W020;P55209-2;P55209-3;F8W0J6;H0YIV4;B7Z9C2;H0YHC3;F8VV59;F5H4R6;F8VY35;F8VUX1;F8VXI6;F8W118;F8VRJ2 P55209 NAP1L1 Nucleosome assembly protein 1-like 1 1 LDGLVET(0.946)PT(0.054)GYIESLPR;LDGLVET(0.996)PT(0.004)GYIESLPR;LDGLVET(0.996)PT(0.004)GYIESLPR;LDGLVET(0.503)PT(0.283)GYIES(0.214)LPR;LDGLVET(0.999)PT(0.001)GYIESLPR 265.6 6.786299999999998e-69 57147900.0 86758.0 77334.0 106076.0 155219.0 130052.0 118100.0 99065.0 130178.0 95959.0 118757.0 True False 114345.23932149618 102330.7031512055 104669.36293117277 119435.65765964436 111996.52466092615 110715.18833040011 107881.59308566578 110061.98129284677 101031.19683581873 114599.35357681755 0.9977825856133558 0.8929431096887627 0.9133503782027133 1.0422018443549506 0.9772875776812591 0.9661065693200981 0.9413804678518648 0.9604066502789711 0.8816035490819423 1.0 16.806239380711823 LDGLVET(ph)PTGYIESLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 LDGLVETPTGYIESLPR 17 0 P55209;F8W020;P55209-2;P55209-3;F8W0J6;H0YIV4;B7Z9C2;H0YHC3;F8VV59;F5H4R6;F8VY35;F8VUX1;F8VXI6;F8W118;F8VRJ2 P55209 NAP1L1 Nucleosome assembly protein 1-like 1 1 LDGLVET(0.763)PT(0.237)GYIESLPR;LDGLVET(0.5)PT(0.5)GYIESLPR;LDGLVET(0.987)PT(0.009)GYIES(0.004)LPR;LDGLVET(1)PTGYIESLPR;LDGLVET(0.733)PT(0.172)GY(0.025)IES(0.07)LPR;LDGLVET(0.834)PT(0.119)GYIES(0.047)LPR;LDGLVET(0.986)PT(0.014)GYIESLPR 218.66 3.5643e-22 10856240.0 40079.990000000005 34072.600000000006 45552.46 48446.84 55629.50000000001 47395.84999999999 41866.56 44457.9 45270.619999999995 34866.020000000004 True False 46864.740691113715 37455.102550031326 46638.60340506658 45732.52062157446 44729.298814707116 44910.32819037458 37900.65634915428 43290.92723203877 45932.61717390125 41186.95342673757 1.1378540239562915 0.9093924030252838 1.1323635162291448 1.1103642492742865 1.0860064921837589 1.0904018009066891 0.9202102412496014 1.0510835016977815 1.1152225001444975 1.0 15.329899794449688 LDGLVET(ph)PTGYIESLPR ddPTM_PC-9_Lapatinib_30min_R1 4 LDGLVETPTGYIESLPR 17 0 P55209;F8W020;P55209-2;P55209-3;F8W0J6;H0YIV4;B7Z9C2;H0YHC3;F8VV59;F5H4R6;F8VY35;F8VUX1;F8VXI6;F8W118;F8VRJ2 P55209 NAP1L1 Nucleosome assembly protein 1-like 1 1 LDGLVET(1)PTGYIESLPR;LDGLVET(0.753)PT(0.243)GYIES(0.003)LPR;LDGLVET(0.971)PT(0.029)GYIESLPR;LDGLVET(0.858)PT(0.141)GYIES(0.001)LPR 232.01 1.4704e-29 136043100.0 435002.0 394429.0 451629.0 384924.0 446034.0 380747.0 372773.0 333366.0 424451.0 292965.0 True False 428798.79171040386 393515.72388414614 414497.80695835483 413232.59502882103 419799.15705658344 364463.3383746075 392073.3619477027 348855.4013724157 376644.8587128211 343603.6098986746 1.247946119765309 1.1452607380934972 1.2063255303999463 1.2026433457747412 1.2217542102668193 1.060708700010702 1.1410629884340313 1.0152844478999794 1.0961609478546808 1.0 18.390385667943335 -7.103641105484067 1.0220530623392603 1.0399470363116288 1.2046508869179822 0.680761921198477 0.04715598836752898 0.31123242742996354 0.6555696304614596 0.030110978116136163 0.019654750617200116 7.876964614735101e-08 7.103641105484067 0.1647038506063534 LDGLVETPT(ph)GYIESLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LDGLVETPTGYIESLPR 17 0 P55209;F8W020;P55209-2;P55209-3;F8W0J6;H0YIV4;B7Z9C2;H0YHC3;F8VV59;F5H4R6;F8VY35;F8VUX1;F8VXI6;F8W118;F8VRJ2 P55209 NAP1L1 Nucleosome assembly protein 1-like 1 1 LDGLVET(0.012)PT(0.609)GY(0.002)IES(0.376)LPR;LDGLVET(0.398)PT(0.602)GYIESLPR 187.78 5.4264e-08 8567500.0 15816.1 14640.8 16293.1 15332.3 18277.3 14997.7 14708.0 14702.800000000001 16222.9 12158.0 True False 18493.45334778586 16094.241866323622 16681.58929592584 14473.280938987278 14695.994269695875 14211.194210058082 13314.751763301325 14316.867078904303 16460.12922178849 14362.149157324946 1.2876522270591988 1.120601219916678 1.1614967309692603 1.0077378239457744 1.023244787998923 0.9894893900896529 0.9270723773614737 0.9968471237887437 1.1460770279908659 1.0 13.809984030285438 -4.821464206977415 0.8196488569281724 1.0045540958821892 1.412357692336862 0.6571565551661268 0.06061231562272334 1.4863508205924565 0.7979468528013164 0.023532924507083438 0.5476795896768436 1.5084669279522631e-05 4.821464206977415 0.4078035964546727 LDGLVETPT(ph)GYIESLPR ddPTM_PC-9_Lapatinib_30min_R1 1 LDGLVETPTGYIESLPR 17 0 P55209;F8W020;P55209-2;P55209-3;F8W0J6;H0YIV4;B7Z9C2;H0YHC3;F8VV59;F5H4R6;F8VY35;F8VUX1;F8VXI6;F8W118;F8VRJ2 P55209 NAP1L1 Nucleosome assembly protein 1-like 1 1 LDGLVET(0.174)PT(0.569)GYIES(0.257)LPR 140.77 0.00022592 4630600.0 12061.0 9241.4 9122.0 7188.8 10430.0 9917.8 8316.6 9979.5 10035.0 7649.2 True False 11889.007928283481 9220.002106089918 8372.02437193829 7717.4883331338015 9816.527906168963 9493.638813520996 8747.192854563678 10443.18400195588 8904.752626765292 8971.354028081676 1.325218901301756 1.0277157803860975 0.9331951838855769 0.8602367389556707 1.0942080621767647 1.0582169406986381 0.9750136743220321 1.1640588443246311 0.9925762152393148 1.0 13.131110029246553 -4.763136712860961 5.762794123265901 1.01163535995578 1.3380919612197661 0.5842052740558722 0.07946319077767074 0.10524240942306252 12.295715991607809 0.02086203908324368 0.13640259580905162 1.725294695811807e-05 4.763136712860961 0.32645660126398623 LDGLVETPTGYIES(ph)LPR ddPTM_PC-9_AZD4547_30min_R2 5 LDGLVETPTGYIESLPR 17 0 P55209;F8W020;P55209-2;P55209-3;F8W0J6;H0YIV4;B7Z9C2;H0YHC3;F8VV59;F5H4R6;F8VY35;F8VUX1;F8VXI6;F8W118;F8VRJ2 P55209 NAP1L1 Nucleosome assembly protein 1-like 1 1 LDGLVETPT(0.003)GYIES(0.997)LPR;LDGLVET(0.001)PT(0.053)GY(0.001)IES(0.945)LPR;LDGLVET(0.042)PT(0.02)GYIES(0.938)LPR;LDGLVET(0.032)PT(0.336)GY(0.001)IES(0.631)LPR;LDGLVET(0.023)PT(0.017)GYIES(0.96)LPR 150.91 4.8784e-05 25746800.0 51347.9 43096.3 61860.3 91395.4 78929.3 66908.8 61927.9 76845.7 56267.5 64667.7 True False 67675.46409733103 57026.33618092034 61039.99200319802 70325.60257485404 67971.32911389037 62724.98215885772 67439.36312976127 64970.9628035131 59241.68517762209 62403.703506315964 1.084478328926127 0.9138293558995041 0.9781469459904745 1.1269459763351433 1.0892194740815488 1.0051483907923708 1.0806948841255173 1.0411395342415424 0.9493296366877674 1.0 15.929344031580001 LDGLVETPTGYIES(ph)LPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LDGLVETPTGYIESLPR 17 0 P55209;F8W020;P55209-2;P55209-3;F8W0J6;H0YIV4;B7Z9C2;H0YHC3;F8VV59;F5H4R6;F8VY35;F8VUX1;F8VXI6;F8W118;F8VRJ2 P55209 NAP1L1 Nucleosome assembly protein 1-like 1 1 LDGLVETPTGYIES(1)LPR;LDGLVET(0.003)PT(0.051)GYIES(0.946)LPR;LDGLVETPT(0.012)GYIES(0.988)LPR;LDGLVET(0.022)PT(0.317)GYIES(0.661)LPR 146.86 8.6834e-05 13771300.0 38681.200000000004 42808.700000000004 44548.9 54273.6 60070.8 48662.7 45343.4 47377.7 41997.2 39279.4 True False 45229.163171475506 47058.464823157774 45611.1147286441 51232.82614938529 48300.35796184593 46110.74234621265 41048.14489421253 46134.08557582255 42611.329599103476 46400.444284440666 0.9747571142684528 1.0141813413398233 0.9829887500439031 1.104145163682518 1.0409460233992276 0.9937564835273537 0.8846498245271563 0.994259565555336 0.9183388274881716 1.0 15.50185099877925 -7.009014850421625 19.946952312195393 0.9474578400898123 1.0243537819900002 0.37108762977368537 0.04545347591826917 31.525333797678282 69756.20261341285 0.016581140695053228 0.013830985980355443 9.794564929486814e-08 7.009014850421625 0.07689594190018789 LDGLVETPTGYIES(ph)LPR ddPTM_PC-9_Lapatinib_30min_R1 4 LDGLVETPTGYIESLPR 17 0 P55209;F8W020;P55209-2;P55209-3;F8W0J6;H0YIV4;B7Z9C2;H0YHC3;F8VV59;F5H4R6;F8VY35;F8VUX1;F8VXI6;F8W118;F8VRJ2 P55209 NAP1L1 Nucleosome assembly protein 1-like 1 1 LDGLVET(0.004)PT(0.114)GYIES(0.882)LPR;LDGLVETPTGYIES(1)LPR;LDGLVET(0.008)PT(0.187)GY(0.013)IES(0.793)LPR;LDGLVET(0.025)PT(0.002)GYIES(0.973)LPR 167.35 2.1523e-05 18242300.0 56693.9 53105.0 61358.9 47857.0 53066.4 56003.3 48424.3 45466.7 60980.7 47217.9 True False 55885.43458961206 52982.03863526146 56314.20809420349 51376.56342627201 49945.13868455656 53608.16940906862 50931.47331208036 47579.24886634876 54112.41141076101 55379.45110110308 1.009136664926224 0.956709349439654 1.016879130697664 0.9277188994249289 0.9018713203454218 0.9680155426459405 0.9196818007296189 0.8591498817762939 0.9771207611280056 1.0 15.75706313391083 -5.776333471937124 24.910804183421984 0.9295580354327326 0.9904884752289578 0.28664593573463304 0.04088190432461819 252.8365409270941 422876.0454108311 0.011087815854093993 0.016523063194557753 1.673657268945684e-06 5.776333471937124 0.060930439796225144 LDGLVETPTGYIESLPR ddPTM_PC-9_Lapatinib_30min_R1 3 LDGLVETPTGYIESLPR 17 0 P55209;F8W020;P55209-2;P55209-3;F8W0J6;H0YIV4;B7Z9C2;H0YHC3;F8VV59;F5H4R6;F8VY35;F8VUX1;F8VXI6;F8W118;F8VRJ2 P55209 NAP1L1 Nucleosome assembly protein 1-like 1 0 ;; 166.48 0.00010905 9776700.0 37840.2 31574.8 37608.2 33847.6 35233.0 31600.4 32728.5 31409.699999999997 36376.9 27777.2 False True 37300.591808957186 31501.690490549936 34516.19896785017 36336.86541628358 33160.66421074318 30248.924556130303 34423.02158821959 32869.10932874732 32279.750456260957 32578.45200920755 1.1449467211767776 0.966948659244052 1.0594794055314525 1.115365008933322 1.0178710824372834 0.9284948390912232 1.056619313234733 1.0089217658180205 0.9908313153472678 1.0 14.991630434250917 -6.507970467049393 24.575216376390934 0.9981393748524819 1.0637427284961913 0.3119372630605377 0.052047680254864684 769.8298208029829 1269011.1707984484 0.016251253258764146 0.017780026653229798 3.104770711977063e-07 6.507970467049393 0.0656033536437094 LDGSLETTNEILDS(ph)ASHDCPLVTQTYGAAAGK ddPTM_PC-9_AZD4547_30min_R2 1 LDGSLETTNEILDSASHDCPLVTQTYGAAAGK 32 0 Q9Y4P8-4;Q9Y4P8;Q9Y4P8-3;Q9Y4P8-2;Q9Y4P8-5;Q9Y4P8-6 Q9Y4P8-4 WIPI2 WD repeat domain phosphoinositide-interacting protein 2 1 LDGSLET(0.001)T(0.001)NEILDS(0.83)AS(0.164)HDCPLVT(0.004)QT(0.001)YGAAAGK 88.39399999999999 1.2565000000000002e-09 3155100.0 4334.7 5300.3 7669.2 14289.0 9956.3 9262.4 6994.6 13499.0 8026.7 8721.9 True False 5713.044432638937 7013.518321984301 7567.501397033739 10994.891812849322 8574.039603247786 8683.220663772225 7617.105849664336 11413.039726160641 8450.974975167175 8416.548935739747 0.6787870511129875 0.8333009616569014 0.8991216536387447 1.3063420526388183 1.0187120242168706 1.0316842128607002 0.9050153344109148 1.356023687772633 1.0040902797203783 1.0 13.039013086374426 -5.408912145512008 2.809465922546153 1.090798278565905 0.7453077840674451 0.4780869575226404 0.13934290477590475 0.22695274100394672 3.409045203122461 0.037792009320182646 0.09414430337859585 3.900208769694901e-06 5.408912145512008 -0.3454904944984598 LDGSLETTNEILDS(ph)ASHDCPLVTQTYGAAAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LDGSLETTNEILDSASHDCPLVTQTYGAAAGK 32 0 Q9Y4P8-4;Q9Y4P8;Q9Y4P8-3;Q9Y4P8-2;Q9Y4P8-5;Q9Y4P8-6 Q9Y4P8-4 WIPI2 WD repeat domain phosphoinositide-interacting protein 2 1 LDGS(0.009)LET(0.009)T(0.034)NEILDS(0.447)AS(0.447)HDCPLVT(0.05)QT(0.002)Y(0.001)GAAAGK;LDGSLETTNEILDS(0.868)AS(0.132)HDCPLVTQTYGAAAGK 114.98 3.4063000000000005e-09 0.0 6401.6 8629.6 7767.3 11189.5 11082.5 8070.5 9389.5 7221.3 7380.700000000001 3561.7000000000003 True False 7485.264442636676 9486.289656960447 7952.501889649288 10562.58859184846 8910.963681391919 7647.268772696726 8500.05858590684 7031.748526599806 7488.6287745874315 4207.408015598315 1.7790678762045933 2.2546635890295152 1.8901190139312891 2.5104740383364996 2.117922399813828 1.8175724209170252 2.0202601113070533 1.6712780173757062 1.7798674972392736 1.0 12.038716015660977 -8.833414829461775 0.5399753465811691 0.9694240897774119 2.1185750798648466 0.6947362826389584 0.21083462484625848 0.7659790226880628 0.45819374002018337 0.26657124332126686 0.10165102357445926 1.4675238583321096e-09 8.833414829461775 1.1491509900874348 LDGSLETTNEILDSAS(ph)HDCPLVTQTYGAAAGK ddPTM_PC-9_AZD4547_30min_R2 1 LDGSLETTNEILDSASHDCPLVTQTYGAAAGK 32 0 Q9Y4P8-4;Q9Y4P8;Q9Y4P8-3;Q9Y4P8-2;Q9Y4P8-5;Q9Y4P8-6 Q9Y4P8-4 WIPI2 WD repeat domain phosphoinositide-interacting protein 2 1 LDGSLETTNEILDS(0.417)AS(0.582)HDCPLVT(0.001)QTYGAAAGK 95.654 5.6338e-13 2111000.0 4366.7 6759.0 10060.0 14354.0 9364.7 10391.0 7104.1 11258.0 10304.0 10228.0 True False 5755.219766997587 8943.714570551083 9926.597826912774 11044.907067089314 8064.573051488462 9741.249127359777 7736.351137534728 9518.334783103672 10848.648403967085 9869.920833160912 0.5831069837623446 0.9061586938470706 1.0057423959837084 1.119047179181082 0.8170858903339071 0.9869632484417885 0.7838311237048805 0.964378027341822 1.0991626566565609 1.0 13.268822797503415 -4.767782292581614 3.6129985893730776 0.9640856902412862 0.533865988340605 0.5732600117075786 0.09999628749330541 0.21747409583160332 4.751798221135284 0.02567242011736737 0.26014805045095324 1.706937845196433e-05 4.767782292581614 -0.43021970190068126 LDHEGVT(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 1 LDHEGVTSPK 10 0 H9KVB4;O15417;H7BXS9;F8WBW8;Q9P281 H9KVB4;F8WBW8 TNRC18;BAHCC1 Trinucleotide repeat-containing gene 18 protein;BAH and coiled-coil domain-containing protein 1 1 LDHEGVT(0.586)S(0.414)PK 81.676 0.033464999999999995 9525900.0 125470.0 103020.0 100380.0 120940.0 115420.0 112400.0 110990.0 121920.0 98882.0 127230.0 True False 165366.85006187408 136319.20033409877 99048.89561287325 93059.15150437366 99395.92529422164 105371.61023147329 120867.89498387992 103080.06544288507 104108.70064839616 122775.71642579799 1.3469019353009999 1.1103107707498987 0.8067466311445673 0.75796056592849 0.8095731646924952 0.8582447188989263 0.9844609219358854 0.8395802398366261 0.8479584047983656 1.0 16.905665715466718 -4.993470653861161 2.8010496993613025 0.8563722371501661 1.350357331360708 0.8150962911830055 0.07362384589931661 0.12210559576727767 1.745355735965048 0.020276461027142027 0.11136757786225285 1.0151479598146673e-05 4.993470653861161 0.49398509421054193 LDHEGVTS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 LDHEGVTSPK 10 0 H9KVB4;O15417;H7BXS9;F8WBW8;Q9P281 H9KVB4;F8WBW8 TNRC18;BAHCC1 Trinucleotide repeat-containing gene 18 protein;BAH and coiled-coil domain-containing protein 1 1 LDHEGVT(0.386)S(0.614)PK 62.088 0.034587 14751000.0 96250.0 94062.0 105620.0 112670.0 106050.0 112900.0 95768.0 101120.0 96989.0 110690.0 True False 126855.49787563123 124465.70201733639 104219.40978911788 86695.6722341474 91326.78805624864 105840.34515243203 104291.16647280105 85494.22750643495 102115.6405330321 106814.77679141388 1.1876212419874503 1.1652479718268844 0.97570217267444 0.8116449318940698 0.8550014408080454 0.9908773704514244 0.9763739587871733 0.8003970056819635 0.9560066837235621 1.0 16.70475171817602 -5.323047110156422 3.3978237125064368 0.9073499458697216 1.1836915452365908 0.6966995112484197 0.06836922055119599 0.12558959736954867 2.860013893089748 0.018721354422711348 0.047061165883100026 4.752836666822677e-06 5.323047110156422 0.2763415993668692 LDHEGVTS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LDHEGVTSPK 10 0 H9KVB4;O15417;H7BXS9;F8WBW8;Q9P281 H9KVB4;F8WBW8 TNRC18;BAHCC1 Trinucleotide repeat-containing gene 18 protein;BAH and coiled-coil domain-containing protein 1 1 LDHEGVT(0.164)S(0.836)PK 73.082 0.027744 0.0 70412.0 67976.0 62817.0 66447.0 73214.0 64085.0 72707.0 65587.0 58527.0 61497.0 True False 82331.36089960825 74724.20804226646 64314.79551479916 62724.190014080596 58868.242271096635 60724.26978480515 65819.66660690427 63865.410745170724 59382.846652794215 72645.91929001582 1.133323959614667 1.028608472059576 0.8853187645412361 0.8634234465899473 0.8103447908214063 0.8358937484483159 0.9060339142263463 0.8791328042833115 0.817428525003958 1.0 16.148594139755748 -5.070468513743258 2.0486023652589673 0.8647480371745837 1.1454263919418881 0.734133204878023 0.05141429888763319 0.19733078089017533 1.3531024736377075 0.01358210013364666 0.08283315717768641 8.502203317446207e-06 5.070468513743258 0.2806783547673044 LDHEGVTS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 LDHEGVTSPK 10 0 H9KVB4;O15417;H7BXS9;F8WBW8;Q9P281 H9KVB4;F8WBW8 TNRC18;BAHCC1 Trinucleotide repeat-containing gene 18 protein;BAH and coiled-coil domain-containing protein 1 1 LDHEGVT(0.221)S(0.779)PK;LDHEGVT(0.027)S(0.973)PK 101.71 0.0019815 26377000.0 290790.0 260620.0 237290.0 263170.0 302240.0 279480.0 275230.0 268290.0 273440.0 235050.0 True False 286643.2812756452 260016.5504024446 217780.9321658887 282524.39970938425 284462.83742670243 267527.2918997003 289480.0626892672 280755.73284079763 242642.30774914828 275678.0793155615 1.0397753857952996 0.9431890669290772 0.7899827679682886 1.0248344750907306 1.0318660015803622 0.9704336759886838 1.0500655815942004 1.0184187786632968 0.8801654028915442 1.0 18.07262502970645 LDHIIK ddPTM_PC-9_Lapatinib_30min_R1 1 LDHIIK 6 0 B5MCF9;O00541-2;O00541 B5MCF9 PES1 Pescadillo homolog 0 69.432 0.041151 0.0 21858.0 28581.0 28664.0 27133.0 28410.0 26329.0 28810.0 25771.0 28210.0 28506.0 False True 21546.300911733724 28514.82245051142 26307.356566239745 29128.451333034638 26738.97965620903 25202.9700458967 30301.640831587374 26968.41474166092 25032.69273553053 33433.22411814259 0.6444577655925678 0.8528888015630477 0.7868626870468055 0.8712426665793216 0.7997726920299942 0.7538300810247095 0.9063331949234337 0.8066351796154313 0.7487370241970321 1.0 15.028994866869994 -12.046686489720015 2.140332376000463 3.608738816272707 0.8026425156051746 0.4315267520334154 0.06968966002236562 6850523.969244179 312057.4047943873 87163545.8769989 0.017356076141648465 8.980768679646826e-13 12.046686489720015 -2.8060963006675324 LDHLAEK ddPTM_PC-9_AZD4547_30min_R2 3 LDHLAEK 7 0 O43707;O43707-2;P12814-4;P12814-3;P12814;P12814-2;H9KV75 O43707;P12814-4 ACTN4;ACTN1 Alpha-actinin-4;Alpha-actinin-1 0 ;; 109.86 0.0080151 62229400.0 427058.0 402582.0 505643.0 664960.0 576541.0 498350.0 441934.0 537012.0 445011.0 473897.0 False True 562853.5606417777 532708.7585799077 498937.84343873337 511663.7455295878 496498.23397206527 467188.09571934806 481265.2698603998 454029.134708124 468533.3729520376 457306.01027301967 1.230802893462398 1.164884665001169 1.091037144123382 1.1188651232117321 1.085702402370892 1.0216093495915977 1.0523921817101771 0.992834392089141 1.024551093637092 1.0 18.802800354732135 -1.522878745280358 0.27143268216925553 0.9919562894532965 2.722294578401486 0.9176364498508263 0.020858866946328734 13.174654334889894 0.1842566280504027 0.02431113586340365 10.698187392080639 0.029999999999998583 1.522878745280358 1.7303382889481895 LDHLAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LDHLAEK 7 0 O43707;O43707-2;P12814-4;P12814-3;P12814;P12814-2;H9KV75 O43707;P12814-4 ACTN4;ACTN1 Alpha-actinin-4;Alpha-actinin-1 0 ;;; 101.33 0.0094288 50766000.0 463552.0 444126.0 447499.0 533602.0 559794.0 465015.0 536947.0 487274.0 433300.0 383629.0 False True 542022.1980306659 488215.8941535204 458169.0733094083 503706.0099010252 450106.384214853 440628.7947878781 486083.4930003642 474483.5738094792 439636.1927769353 453177.900894508 1.1960472850966297 1.0773162000835708 1.0110137153754595 1.1114972925793203 0.9932222717092067 0.9723086538821515 1.072610760676779 1.0470139273625587 0.9701183396391498 1.0 18.78971798465249 -1.5228789839153989 0.8641796793516677 1.0203813987546395 69.39365061816778 0.6154508632054738 0.04196710879803938 489.90904687416577 1.2800241435327753 0.014390838908458317 65916.94943006044 0.029999983515678483 1.5228789839153989 68.37326921941315 LDHLAEK ddPTM_PC-9_Lapatinib_30min_R1 2 LDHLAEK 7 0 O43707;O43707-2;P12814-4;P12814-3;P12814;P12814-2;H9KV75 O43707;P12814-4 ACTN4;ACTN1 Alpha-actinin-4;Alpha-actinin-1 0 ; 100.45 0.009665100000000001 67500000.0 664940.0 741390.0 723750.0 700380.0 738560.0 643050.0 635460.0 615280.0 691500.0 623220.0 False True 655457.833664939 739673.3570058657 664246.0687557921 751888.2815991903 695119.352864828 615548.250522765 668361.0094703408 643868.154990071 613615.9881821821 730942.7466115508 0.8967293768266543 1.0119443149751297 0.9087525279306128 1.0286555069938614 0.9509901508527306 0.8421292274617637 0.91438216271887 0.8808735813781126 0.8394857066804983 1.0 19.479398881415584 -6.6113401772703 7.798677486864743 0.8893792879297515 0.9648287527627791 0.24158090405835675 0.056338315479780895 0.29556921388819185 22.642825322244555 0.01737577208668695 0.017363671889718203 2.447145673273409e-07 6.6113401772703 0.07544946483302761 LDHYAIIK ddPTM_PC-9_Lapatinib_30min_R1 2 LDHYAIIK 8 0 P62750;H7BY10;K7EJV9;K7ERT8;A8MUS3 P62750 RPL23A 60S ribosomal protein L23a 0 ; 81.548 0.014879 6797800.0 147605.0 181922.0 202872.0 206110.0 206470.0 184382.0 208790.0 211400.0 191895.0 193474.0 False True 145500.12563255784 181500.7707862541 186192.64726856616 221268.01696280445 194325.84053563824 176496.41167543485 219600.12458268384 221222.41575364236 170281.76435606662 226915.72311209998 0.6412077736926077 0.7998598259169103 0.8205365618343865 0.975110996841301 0.8563789140324939 0.777806003280975 0.9677607244263011 0.9749100358477802 0.7504185343381636 1.0 17.791797052023327 -4.541439196955521 1.1564941071950834 0.8947596622602082 0.4040233098337477 0.46980614003683485 0.08281622618230951 2.289429005685938 1.7983348555836254 0.025052938909483728 1.5528196559980934 2.8744900060718683e-05 4.541439196955521 -0.4907363524264605 LDIDS(ph)PPITAR ddPTM_PC-9_AZD4547_30min_R2 16 LDIDSPPITAR 11 0 P14618;P14618-2;H3BTN5;B4DNK4;H3BQ34;H3BUW1;H3BTJ2;H3BT25;H3BU13;H3BN34;H3BQZ3 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 1 LDIDS(1)PPITAR;LDIDS(1)PPITAR;LDIDS(1)PPITAR;LDIDS(0.9)PPIT(0.1)AR;LDIDS(0.996)PPIT(0.004)AR;LDIDS(1)PPITAR;LDIDS(1)PPITAR;LDIDS(1)PPITAR;LDIDS(1)PPITAR;LDIDS(1)PPITAR;LDIDS(0.998)PPIT(0.002)AR;LDIDS(1)PPITAR;LDIDS(1)PPITAR;LDIDS(1)PPITAR;LDIDS(1)PPITAR;LDIDS(0.955)PPIT(0.045)AR 201.38 5.3105e-47 39954430.0 716435.8 700063.8 879532.4 1292244.7 1025473.2 983837.0999999999 780068.0 1060560.7 862185.4 895091.0000000001 True False 944247.4816096224 926345.7328562441 867869.2256997383 994337.6493965932 883103.9471359061 922317.6106091033 849492.5408080468 896675.4130753921 907758.7600576192 863754.136534496 1.0931901124063812 1.0724645980543428 1.004764190400005 1.1511813458700375 1.0224019889259741 1.0678010924608388 0.983488824975509 1.0381141752593868 1.0509457745692263 1.0 19.72026118904742 -6.760928812533372 2.011058143990625 1.0235403256506492 1.0733318253824116 0.2494931683740721 0.04134246399903116 0.4974439253991054 4.143840702616052 0.016140479759793276 0.014829946950665373 1.7340882178756269e-07 6.760928812533372 0.049791499731762334 LDIDS(ph)PPITAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 20 LDIDSPPITAR 11 0 P14618;P14618-2;H3BTN5;B4DNK4;H3BQ34;H3BUW1;H3BTJ2;H3BT25;H3BU13;H3BN34;H3BQZ3 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 1 LDIDS(1)PPITAR;LDIDS(1)PPITAR;LDIDS(0.999)PPIT(0.001)AR;LDIDS(0.999)PPIT(0.001)AR;LDIDS(1)PPITAR;LDIDS(0.995)PPIT(0.005)AR;LDIDS(1)PPITAR;LDIDS(1)PPITAR;LDIDS(1)PPITAR;LDIDS(0.968)PPIT(0.032)AR;LDIDS(1)PPITAR;LDIDS(1)PPITAR;LDIDS(1)PPITAR;LDIDS(0.998)PPIT(0.002)AR;LDIDS(1)PPITAR;LDIDS(0.999)PPIT(0.001)AR;LDIDS(1)PPITAR;LDIDS(0.906)PPIT(0.094)AR;LDIDS(1)PPITAR;LDIDS(0.998)PPIT(0.002)AR 187.78 1.8468e-35 54180400.0 716932.4 771238.5 726943.0 860241.4 958165.3 816111.3999999999 841675.7 815626.2 773268.3999999999 665485.3 True False 838294.8952596503 847801.9613423207 744276.0780666809 812044.8632982463 770419.6877121578 773313.0815019897 761946.084491628 794216.8764773922 784575.9874699105 786132.5169112644 1.066353162127593 1.0784466271327349 0.9467565099468999 1.0329618045680036 0.9800124929816634 0.9836930350373464 0.9692336445836568 1.010283710942134 0.9980200164630392 1.0 19.58441299986758 -5.24395530916142 24.927695347037236 0.9906810118762659 1.072399913733579 0.6868326884830602 0.022221079825651687 415.66170259156445 592622.296272654 0.005374602857835667 0.014145612695955783 5.702229477454931e-06 5.24395530916142 0.08171890185731301 LDIDS(ph)PPITAR ddPTM_PC-9_Lapatinib_30min_R1 13 LDIDSPPITAR 11 0 P14618;P14618-2;H3BTN5;B4DNK4;H3BQ34;H3BUW1;H3BTJ2;H3BT25;H3BU13;H3BN34;H3BQZ3 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 1 LDIDS(1)PPITAR;LDIDS(1)PPITAR;LDIDS(1)PPITAR;LDIDS(1)PPITAR;LDIDS(0.999)PPIT(0.001)AR;LDIDS(0.998)PPIT(0.002)AR;LDIDS(1)PPITAR;LDIDS(1)PPITAR;LDIDS(1)PPITAR;LDIDS(0.942)PPIT(0.058)AR;LDIDS(0.995)PPIT(0.005)AR;LDIDS(1)PPITAR;LDIDS(0.973)PPIT(0.027)AR 189.3 5.6067e-05 53166590.0 994952.4 887968.1 993151.4999999998 864285.2000000001 992327.7 928822.6 850184.4 849824.6000000001 1010781.0999999997 788208.9999999999 True False 980764.1963240772 885912.0644210482 911498.4173456556 927847.6167789077 933960.9356773208 889099.0225892322 894202.788247781 889310.5533532319 896936.2885211468 924449.875427527 1.0609165757856873 0.958312708962553 0.9859900915927088 1.0036754197730942 1.0102883460776013 0.9617601194202701 0.9672809873377313 0.9619889374120534 0.970237881319789 1.0 19.818235571856896 -6.763900954223534 24.99947804810058 0.9695671041041851 1.0003070925798152 0.2604048353082258 0.026082947496709384 93.88076250337485 953433.9722259997 0.008724829949760274 0.008056163284931797 1.722261311402864e-07 6.763900954223534 0.030739988475630087 LDIDSPPIT(ph)AR ddPTM_PC-9_AZD4547_30min_R2 3 LDIDSPPITAR 11 0 P14618;P14618-2;H3BTN5;B4DNK4;H3BQ34;H3BUW1;H3BTJ2;H3BT25;H3BU13;H3BN34;H3BQZ3 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 1 LDIDS(0.024)PPIT(0.976)AR;LDIDS(0.003)PPIT(0.997)AR;LDIDS(0.018)PPIT(0.982)AR 135.94 0.00011778 0.0 40256.0 55113.0 60051.0 87650.0 79059.0 70227.0 49823.0 70730.0 56225.0 60271.0 True False 53056.57062318333 72927.19945654413 59254.684503373624 67443.64667900089 68083.02250767528 65835.6945883067 54257.150480059805 59800.30371370783 59196.93871438753 58160.93063506466 0.9122373050749646 1.253886391779588 1.0188056459270194 1.1596039805858913 1.170597199258512 1.1319573787668211 0.9328796820755942 1.0281868439989301 1.0178127837366184 1.0 15.827762733604944 -7.246378038364198 24.688130089273617 0.9970687300918532 1.1156435022751756 0.27338384649389935 0.08978240778934736 845.1488424701747 1385346.6095323737 0.03236459359429197 0.02495993388726807 5.6705079236349356e-08 7.246378038364198 0.11857477218332246 LDIDSPPIT(ph)AR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LDIDSPPITAR 11 0 P14618;P14618-2;H3BTN5;B4DNK4;H3BQ34;H3BUW1;H3BTJ2;H3BT25;H3BU13;H3BN34;H3BQZ3 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 1 LDIDS(0.008)PPIT(0.992)AR;LDIDSPPIT(1)AR;LDIDSPPIT(1)AR 130.56 0.00060172 1504200.0 40240.0 44910.0 52947.0 55263.0 60150.0 45515.0 52512.0 43873.0 43402.0 40423.2 True False 47051.83722377216 49368.3680001499 54209.4572826157 52166.79327506335 48364.039290387875 43128.11327542177 47537.68320604296 42721.38023728596 44036.672141482966 47751.60617012489 0.9853456458855089 1.0338577476172208 1.1352384062115815 1.0924615412769247 1.012825393099471 0.9031761805407973 0.9955200886160815 0.894658497665655 0.9222029513435274 1.0 15.543261639916741 -6.55514361613963 4.703711365223379 0.9403237691488632 1.0641470051537005 0.5719721114504346 0.04845217771233339 0.14356028815535785 7.657275708055124 0.01675124199473229 0.0171737551119509 2.7851999830489107e-07 6.55514361613963 0.12382323600483736 LDIDSPPIT(ph)AR ddPTM_PC-9_Lapatinib_30min_R1 3 LDIDSPPITAR 11 0 P14618;P14618-2;H3BTN5;B4DNK4;H3BQ34;H3BUW1;H3BTJ2;H3BT25;H3BU13;H3BN34;H3BQZ3 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 1 LDIDSPPIT(1)AR;LDIDSPPIT(1)AR;LDIDSPPIT(1)AR 111.31 0.0044686000000000005 5897000.0 57443.0 57005.0 64355.0 46101.0 63310.0 61698.0 61821.0 59290.0 61226.0 45199.0 True False 56623.85228624394 56873.00842487679 59063.98031748394 49491.421328427714 59586.230272249 59059.32036506268 65021.78888752387 62044.82984878648 54330.083141637486 53011.58692611826 1.068141053109013 1.0728410848017087 1.1141711414864988 0.9335962984357257 1.1240227604446884 1.1140832370736815 1.226558053773114 1.1704012923676057 1.0248718495704874 1.0 15.694020108542947 -6.441195341857516 24.99999535718106 1.124609064996556 1.050679881090172 0.12564326135494608 0.07524092756981364 170.95159981604476 52319.578315741055 0.023289044141226498 0.02640728701114262 3.620801013235332e-07 6.441195341857516 -0.07392918390638403 LDIDSPPITAR ddPTM_PC-9_AZD4547_30min_R2 4 LDIDSPPITAR 11 0 P14618;P14618-2;H3BTN5;B4DNK4;H3BQ34;H3BUW1;H3BTJ2;H3BT25;H3BU13;H3BN34;H3BQZ3 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ;;; 182.16 0.00030253 34220600.0 50317.4 46942.1 70012.0 89751.0 74328.0 69607.0 57479.0 73772.0 62341.0 60768.0 False True 66317.28653306256 62115.215822202365 69083.59513497191 69060.2935891272 64008.840194670825 65254.463286318256 62594.51964842255 62372.23251191366 65636.21798832597 58640.53081633967 1.1309121116377043 1.0592539828253824 1.1780861150684259 1.177688752603927 1.091546057029131 1.112787731930552 1.0674275757234644 1.063636901706459 1.1192978145763477 1.0 15.839610542411263 -7.010547820961461 1.53024882429249 1.0661355708058167 1.1314752499512586 0.3494201175940319 0.0424813858153786 0.5173458372651306 2.450743351101523 0.021816196538223705 0.01609742039260784 9.7600530677981e-08 7.010547820961461 0.06533967914544192 LDIDSPPITAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LDIDSPPITAR 11 0 P14618;P14618-2;H3BTN5;B4DNK4;H3BQ34;H3BUW1;H3BTJ2;H3BT25;H3BU13;H3BN34;H3BQZ3 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ;; 183.72 0.00080612 25641700.0 44721.0 52092.0 58802.0 61605.0 58825.0 52835.0 64016.0 53543.0 56341.0 46306.0 False True 52291.38201998792 57263.349495965434 60204.06268782681 58153.47157610477 47298.66352879578 50064.23958929825 57951.94104429548 52137.55298349792 57164.88053829988 54700.91124190568 0.9559508394428382 1.0468445259116033 1.1006043833819215 1.0631170533691974 0.864677798869297 0.915235933966392 1.0594328271427265 0.9531386552762945 1.0450443921399721 1.0 15.739277246081508 LDIDSPPITAR ddPTM_PC-9_Lapatinib_30min_R1 4 LDIDSPPITAR 11 0 P14618;P14618-2;H3BTN5;B4DNK4;H3BQ34;H3BUW1;H3BTJ2;H3BT25;H3BU13;H3BN34;H3BQZ3 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ;;; 212.21 2.8685e-06 127617000.0 162580.0 157156.0 174994.0 170100.0 173590.0 161209.0 166637.0 145681.0 157830.0 162294.0 False True 160261.5793864793 156792.11493763622 160606.66881637467 182609.72143696566 163379.77749107112 154314.4668665337 175264.648498897 152449.8710946377 140053.52337641935 190346.30165683784 0.8419474294562539 0.8237203117311197 0.8437603852473126 0.959355237519561 0.8583291404611433 0.8107037831748187 0.9207672908448177 0.8009079754513907 0.7357827399710247 1.0 17.538267013692526 LDIPTGTT(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 2 LDIPTGTTPQR 11 0 P52732 P52732 KIF11 Kinesin-like protein KIF11 1 LDIPT(0.01)GT(0.032)T(0.958)PQR;LDIPT(0.019)GT(0.076)T(0.905)PQR 125.36 0.0011371999999999999 13043700.0 122478.0 153463.0 149906.0 119832.0 122704.0 140106.0 158313.0 194681.0 146802.0 124957.0 True False 161423.45629934044 203066.91361747004 147918.14849315945 92206.58378594443 105668.66762521389 131345.14967162634 172402.5503070816 164597.52477433017 154561.65401777707 120582.29346395086 1.3386995027391762 1.6840525070803922 1.2266987485802041 0.7646776416100461 0.8763199354539103 1.089257351958504 1.429750134571979 1.3650223432144128 1.2817939481635803 1.0 16.879658549110914 -5.44905479279573 6.745849533996219 1.1224846783929392 1.5031651673749875 0.3546871153059735 0.21058260824379804 0.3032333512817448 23.15962458778284 0.06268140439583104 0.1310073207575722 3.55586453147414e-06 5.44905479279573 0.3806804889820483 LDIPTGTT(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 2 LDIPTGTTPQR 11 0 P52732 P52732 KIF11 Kinesin-like protein KIF11 1 LDIPT(0.055)GT(0.202)T(0.743)PQR;LDIPT(0.038)GT(0.172)T(0.79)PQR 101.72 0.0088439 13006100.0 57844.0 144475.0 136135.0 122851.0 148946.0 122643.0 145344.0 146300.0 118124.0 112142.0 True False 57019.13395270953 144140.47701401767 124942.5057962967 131885.8723589225 140185.28911910302 117397.84478479663 152869.20114634623 153097.63209440824 104819.63121913545 131525.5952801775 0.4335212004267811 1.0959119911753128 0.949948225135515 1.002739216484651 1.0658403698571257 0.8925855422643344 1.1622772040734908 1.1640139835009125 0.7969523422102545 1.0 17.004984054110857 -4.756891626489895 24.999371470546922 1.0196316163219579 0.43352032328549905 0.7159794798148673 0.10972754600993434 71.39851059214736 392435.1319547783 0.026396635339729288 0.2056420468861738 1.7502833985037872e-05 4.756891626489895 -0.5861112930364588 LDLAGTLPGS(ph)KR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LDLAGTLPGSKR 12 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 LDLAGT(0.001)LPGS(0.999)KR 61.443999999999996 0.025580000000000002 5263100.0 34170.0 24382.0 33382.0 31353.0 35826.0 24259.0 29462.0 22411.0 20507.0 18057.0 True False 39954.30611173694 26802.483824975603 34177.95348193997 29596.393057797464 28806.152479092874 22986.815334471197 26671.146073591513 21822.73499641729 20806.87607956756 21330.591160866643 1.8730988658691088 1.2565279425610931 1.6022975277236222 1.38750927410279 1.350461984942123 1.0776454886371403 1.2503706940163344 1.0230722079776926 0.9754476996277582 1.0 14.380636328961282 -5.401121303449012 0.3153721154236931 0.934263431699527 2.0446422680611813 0.7242310086627177 0.14397800297686647 2.6558470717098577 0.29007028067641183 0.1581236754386025 1.0983494259351165 3.9708062478862985e-06 5.401121303449012 1.1103788363616545 LDLLEDR ddPTM_PC-9_AZD4547_30min_R2 2 LDLLEDR 7 0 F5H6X6;Q14697;Q14697-2;E9PKU7;E9PNH1 F5H6X6 GANAB Neutral alpha-glucosidase AB 0 ; 116.9 0.025564 5288900.0 50729.1 49448.9 64700.0 87253.0 69942.1 61560.7 56520.9 71382.9 57918.7 60601.9 False True 66859.89856917056 65432.2898990566 63842.03572577103 67138.16889541203 60231.84670352618 57711.29969730124 61551.150604508206 60352.3130208572 60980.16423863045 58480.245926782736 1.1432903112767199 1.118878500972411 1.0916854865094319 1.1480486757779544 1.0299520077076358 0.9868511799617906 1.0525118290639586 1.0320119565916035 1.042748081377387 1.0 15.83566175781319 -6.273110861464243 23.88186935727468 1.0251799941192838 1.1225909203320164 0.8238551158414941 0.022964614718307692 166.5059353765533 340699.03242774645 0.007106638235468838 0.008128324366896738 5.33198769554578e-07 6.273110861464243 0.09741092621273251 LDLLEDR ddPTM_PC-9_Lapatinib_30min_R1 1 LDLLEDR 7 0 F5H6X6;Q14697;Q14697-2;E9PKU7;E9PNH1 F5H6X6 GANAB Neutral alpha-glucosidase AB 0 101.64 0.013784000000000001 0.0 9896.0 13514.0 9238.0 8918.1 10466.0 12786.0 7759.4 9356.9 11503.0 6407.8 False True 9754.881225295865 13482.709163297686 8478.487299711236 9573.966823909492 9850.410456947697 12239.172585621758 8161.143764964213 9791.655733042844 10207.411008039979 7515.379692143201 1.2979891402551365 1.7940157005497548 1.1281515568102163 1.2739165838711246 1.3107003053013548 1.6285501314613484 1.0859256749856714 1.3028823737647386 1.3582029686019863 1.0 12.875630278508897 -14.04031791745768 0.11400710753084949 6.452593700088763e-13 1.5485766107344312 0.23890020632077358 0.1986145420159072 210.83238831004314 1.7595596012209433 50.58345098857918 2.2944354825087716 9.113434625385932e-15 14.04031791745768 1.548576610733786 LDLLGNLPGS(ph)K ddPTM_PC-9_AZD4547_30min_R2 2 LDLLGNLPGSK 11 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 LDLLGNLPGS(1)K;LDLLGNLPGS(1)K 115.1 0.0013927 2881000.0 62115.0 79125.0 58053.0 67765.0 61520.0 84913.0 71401.0 74199.0 65884.0 65741.0 True False 81866.27792773825 104700.60887629155 57283.17928884364 52142.8262088133 52979.00991249798 79603.37668670027 77755.55067793485 62733.24947339757 69366.49373514813 63439.42760000313 1.290463691506167 1.650402798973022 0.9029586403273413 0.8219309060854566 0.8351117265202967 1.254793425763765 1.2256660190599042 0.9888684662942083 1.0934287454879985 1.0 15.953092133530143 -5.266484028306025 24.99199270282909 1.017665863282509 1.4704332532156372 0.5641749692634348 0.15998406887548075 289.5782815216497 1434623.6407084162 0.04507580630494135 0.09866608472650701 5.413971580383228e-06 5.266484028306025 0.45276738993312815 LDLLGNLPGS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LDLLGNLPGSK 11 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 LDLLGNLPGS(1)K 95.195 0.015952 0.0 24098.0 27396.0 20702.0 22246.0 21049.0 15579.0 18755.0 13482.0 13816.0 14436.0 True False 28177.315442804702 30115.69382614353 21195.614192772213 20999.628742505105 16924.599551510804 14762.009814737903 16978.39062555863 13128.111785359786 14018.032862695936 17053.13252468687 1.6523248970248705 1.7659918951868063 1.242916171682153 1.231423535359566 0.9924627939770013 0.8656479853990324 0.9956171161503589 0.7698357921252855 0.8220209889533675 1.0 14.05774915473603 -5.590628909947601 0.9029547160514305 0.870785341746209 1.8310299683852027 0.9034649389082344 0.10060791785869345 0.22579893618665567 0.30503010359844906 0.039322986965278896 0.16892478525207158 2.5666762384668565e-06 5.590628909947601 0.9602446266389937 LDLLGNLPGS(ph)KR ddPTM_PC-9_Lapatinib_30min_R1 1 LDLLGNLPGSKR 12 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 LDLLGNLPGS(1)KR 56.793 0.034422 4481300.0 14183.0 24117.0 31729.0 22477.0 22990.0 21509.0 20737.0 19509.0 19777.0 14029.0 True False 13980.747819156342 24061.15856824406 29120.364097481888 24130.03356107395 21637.773400079044 20589.11020992792 21810.660393079736 20415.459361106 17549.505998957367 16453.89395753252 0.8496923497404708 1.46233825441843 1.7698159580122195 1.466524193200317 1.315054871261849 1.2513214357080693 1.3255622316135636 1.2407676513412738 1.0665867936339337 1.0 14.006141430283174 -8.049891011073036 0.8490739253474364 0.9920805648160337 1.3950688152836268 0.2480345302984257 0.21634898597600438 0.8263350615739474 1.1773437477920883 0.212493616739084 0.08375033031927992 8.914746312198323e-09 8.049891011073036 0.4029882504675931 LDLT(ph)Y(ph)DET(ph)T(ph)S(ph)DEEK ddPTM_PC-9_Lapatinib_30min_R1 1 LDLTYDETTSDEEK 14 0 Q96M61 Q96M61 MAGEB18 Melanoma-associated antigen B18 5 LDLT(1)Y(1)DET(1)T(1)S(1)DEEK 43.77 0.027977 3147500.0 5104.9 3604.9 3868.7 3242.3 4636.9 4295.6 3357.3 3981.9 3373.2 3120.5 True False 5032.103189875991 3596.5530755343975 3550.6304196138594 3480.7495579957326 4364.166658496156 4111.887201532681 3531.1245666049363 4166.913610640626 2993.2746946292673 3659.874267195115 1.3749388155163418 0.9826985336003781 0.9701509288009015 0.9510571412780633 1.1924362259146137 1.1235050445282053 0.9648212776749703 1.1385400990384569 0.8178627122410077 1.0 11.8375783710922 -4.757346304596176 24.999881485342332 1.0238664448400092 1.3749393259641074 0.5172117199465904 0.10385977011490012 101.48644262194361 619780.1889459327 0.02560400851391817 0.1921857665077844 1.7484519243865987e-05 4.757346304596176 0.3510728811240982 LDNLVAILDINR ddPTM_PC-9_Lapatinib_30min_R1 1 LDNLVAILDINR 12 0 P29401;P29401-2;A0A0B4J1R6;E9PFF2 P29401 TKT Transketolase 0 92.85600000000001 0.025956 4859900.0 8090.3 6598.5 7705.2 8931.5 8215.9 7510.3 9415.3 6242.5 6886.0 7694.2 False True 7974.930838420684 6583.221578660632 7071.708198932131 9588.352304610577 7732.656915080882 7189.101976364391 9902.778164583291 6532.549339366661 6110.426167205368 9024.132218122946 0.8837338201234268 0.7295129791471481 0.7836441253298784 1.062523472933444 0.8568864826195226 0.7966529969415443 1.0973662536432902 0.7238977866755432 0.677120638251947 1.0 13.139572490367863 -12.021864864221047 2.3714001134172014 3.2948728854635614 0.8495441132928951 0.1084439229471289 0.13231155578177697 10284837.418941628 2195105.329225706 124679668.66761884 0.03462882188860342 9.509006314177933e-13 12.021864864221047 -2.445328772170666 LDNS(ph)PNMNITQPSK ddPTM_PC-9_AZD4547_30min_R2 3 LDNSPNMNITQPSK 14 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 LDNS(1)PNMNITQPSK;LDNS(1)PNMNITQPSK;LDNS(1)PNMNITQPSK 172.42 0.00014380000000000003 19472800.0 56630.0 62344.0 70279.0 83127.0 75399.0 70974.0 60229.0 80388.0 59250.0 67697.0 True False 74637.1620228258 82495.47879663213 69347.05454051722 63963.35444934749 64931.150331476616 66535.98456021864 65589.26432096661 67965.8817324693 62381.83403872759 65326.94863536317 1.142517193622951 1.262809307948836 1.0615382470654362 0.9791266205677708 0.9939412706064722 1.0185074605520605 1.004015428411751 1.0403957807953945 0.9549173096531052 1.0 15.995390633838651 -5.4372953714864085 4.433850040557429 1.0020864751269245 1.2005571716802617 0.8419632788932162 0.034817402352136734 0.07229331065409843 2.5015703086052383 0.008690813033614415 0.018701801081000266 3.6534622855708944e-06 5.4372953714864085 0.19847069655333716 LDNS(ph)PNMNITQPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LDNSPNMNITQPSK 14 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 LDNS(0.997)PNMNIT(0.003)QPSK;LDNS(0.717)PNMNIT(0.282)QPS(0.001)K;LDNS(0.501)PNMNIT(0.499)QPSK 119.04 0.0014458000000000001 11697700.0 85721.0 80664.0 81208.0 104524.0 112891.0 94472.0 90967.0 84224.0 80615.0 69204.0 True False 100231.87223307579 88671.78883019551 83144.3067030549 98667.85915138021 90770.81894482407 89517.7220115489 82349.94721595262 82013.20924270438 81793.84186640379 81750.1373814374 1.226075887376245 1.0846683769650738 1.0170540303206153 1.2069442610353855 1.1103445431693546 1.0950161660752789 1.0073371110279188 1.0032179990112986 1.0005346105384811 1.0 16.318933534617074 -7.176771162342355 2.529972461155545 1.0002714123413918 1.1242319289054978 0.5397786686251762 0.05521127039817116 0.251520331182802 3.147346346980002 0.025207428229681823 0.017881751844973846 6.65623793092247e-08 7.176771162342355 0.123960516564106 LDNS(ph)PNMNITQPSK ddPTM_PC-9_Lapatinib_30min_R1 1 LDNSPNMNITQPSK 14 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 LDNS(0.999)PNMNIT(0.001)QPSK 128.74 2.1785999999999998e-05 8246600.0 27622.0 28362.0 33880.0 25252.0 30679.0 26936.0 26125.0 26894.0 28547.0 22869.0 True False 27228.10521474557 28296.32953155609 31094.517180581995 27109.11631820259 28874.5215372347 25784.01007088281 27477.624669393266 28143.593421373964 25331.736246763223 26821.876178972932 1.015145436995608 1.0549720438176902 1.1592968729368234 1.0107091740082985 1.0765287761588782 0.9613052382627969 1.024448270734111 1.0492775834763264 0.9444431134396963 1.0 14.71112253623366 -6.7451514131428585 24.991034136006913 1.0007592756669306 1.0652741791404579 0.3358871222254609 0.04712452235159729 305.1397865323118 468182.8279270019 0.01558344768565072 0.015539048333613302 1.798243863127235e-07 6.7451514131428585 0.06451490347352729 LDNVPHT(ph)PSSYIETLPK ddPTM_PC-9_AZD4547_30min_R2 1 LDNVPHTPSSYIETLPK 17 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;A8MXH2;E9PNW0;E9PJJ2;E9PKI2;E9PP22 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 LDNVPHT(0.764)PS(0.116)S(0.098)Y(0.02)IET(0.003)LPK 74.14699999999999 0.020555 25253000.0 168320.0 139970.0 243400.0 304230.0 275800.0 251190.0 202080.0 291480.0 203350.0 289470.0 True False 221842.2587265061 185212.56523746625 240172.35696526515 234094.4738066446 237509.93065453417 235483.04959113727 220064.72851916705 246438.46354406307 214098.66585274713 279335.74340781086 0.7941778449835964 0.663046422122459 0.8597981555644675 0.8380398117002981 0.8502668786922342 0.8430108038388353 0.7878144265908992 0.8822303244747306 0.7664563912974713 1.0 18.091640665089557 -14.522878745280336 0.1415087839273493 1.616685201605299 0.7486920388848336 0.48077726854638514 0.05946862546963749 124.12019254910524 1.0673385112391398 21.831619425883606 0.35969205500042506 3.0000000000000132e-15 14.522878745280336 -0.8679931627204654 LDNVPHT(ph)PSSYIETLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LDNVPHTPSSYIETLPK 17 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;A8MXH2;E9PNW0;E9PJJ2;E9PKI2;E9PP22 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 LDNVPHT(0.993)PS(0.006)S(0.001)YIETLPK;LDNVPHT(0.999)PS(0.001)SYIETLPK;LDNVPHT(0.999)PSSYIETLPK;LDNVPHT(0.56)PS(0.139)S(0.245)Y(0.056)IETLPK 113.17 0.0012444 37160100.0 202208.0 190137.0 243233.0 225088.0 270513.0 221379.0 218759.0 206420.0 212955.0 165293.0 True False 236437.8206099538 209012.54478834308 249032.59718628944 212477.04910514163 217507.9195438189 209769.49552454334 198036.56384199308 201001.69372006887 216069.06400372114 195259.3124413318 1.2108913918305158 1.0704357306960384 1.27539421332908 1.0881788246027093 1.1139438976011553 1.0743123741540948 1.0142234004920803 1.0294090008150696 1.1065749505219726 1.0 17.575031830448353 -6.449410246821739 1.3308554750051587 1.0410941025678098 1.1705582342328424 0.4857533470309924 0.0588224129621462 0.37821319679717236 1.3762784756375452 0.023648034229169286 0.0282289739064683 3.552955378098644e-07 6.449410246821739 0.12946413166503268 LDNVPHT(ph)PSSYIETLPK ddPTM_PC-9_Lapatinib_30min_R1 2 LDNVPHTPSSYIETLPK 17 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;A8MXH2;E9PNW0;E9PJJ2;E9PKI2;E9PP22 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 LDNVPHT(0.371)PS(0.244)S(0.344)Y(0.04)IETLPK;LDNVPHT(0.584)PS(0.167)S(0.231)Y(0.016)IET(0.001)LPK 72.771 0.024255000000000002 37569000.0 153259.0 114293.0 178009.0 126424.0 141588.0 137623.0 126540.0 125341.0 160793.0 96667.0 True False 151073.4985557416 114028.36158064089 163373.787154611 135721.64269810118 133260.07221271817 131737.1851048823 133091.62203502463 131164.80043981696 142682.79911464592 113375.76214931882 1.332502606304634 1.0057560753634678 1.440993948419447 1.1970957471434878 1.1753841357839006 1.1619519252393735 1.1738983669167269 1.1569033623524356 1.2584947294707398 1.0 16.790752723495764 -5.991453095943605 24.999337872696728 1.165687755684638 1.2484669407193274 0.1314542610356625 0.1180488579499214 481.2222783588879 1407540.2860939065 0.03158689251277842 0.04677414605770009 1.0198749011788886e-06 5.991453095943605 0.0827791850346895 LDNVPHTPS(ph)SYIETLPK ddPTM_PC-9_AZD4547_30min_R2 2 LDNVPHTPSSYIETLPK 17 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;A8MXH2;E9PNW0;E9PJJ2;E9PKI2;E9PP22 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 LDNVPHT(0.205)PS(0.294)S(0.294)Y(0.185)IET(0.023)LPK;LDNVPHTPS(0.764)S(0.227)Y(0.007)IET(0.001)LPK 109.65 0.00025174 15062100.0 63451.0 55157.0 88953.0 111310.0 92398.0 94788.0 83488.0 102663.0 80698.0 96296.0 True False 83627.09813721191 72985.42159607729 87773.42509914227 85649.19922235694 79570.13260557517 88860.89137563079 90918.27026231345 86798.7923110476 84963.5315317679 92924.7063502214 0.8999447124646487 0.7854253670816512 0.944564998336776 0.9217053524985702 0.8562860807510703 0.9562676586862205 0.9784079372783171 0.9340765843683594 0.9143266077328365 1.0 16.50377460360771 -1.5228787452842227 0.14024646412006067 1.008698579195102 0.44596640978681246 0.38951660086765816 0.04591124655562932 75.98994673299534 0.7122681925350177 0.19815133508297986 8.571618802228612 0.029999999999731623 1.5228787452842227 -0.5627321694082895 LDNVPHTPS(ph)SYIETLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LDNVPHTPSSYIETLPK 17 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;A8MXH2;E9PNW0;E9PJJ2;E9PKI2;E9PP22 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 LDNVPHTPS(0.685)S(0.3)Y(0.009)IET(0.006)LPK;LDNVPHT(0.088)PS(0.346)S(0.346)YIET(0.219)LPK 105.06 0.00042332 10322700.0 90284.0 95895.0 109439.0 111014.0 126819.0 110438.0 108236.0 104037.0 93707.0 80024.0 True False 105567.2980097176 105414.82185202336 112048.44080971893 104794.24549224407 101969.727327809 104646.43686501226 97983.10251921951 101306.13898631318 95077.28759877296 94531.7177303644 1.1167394451757484 1.1151264822321452 1.1852999554003452 1.1085617399987566 1.0786826874199014 1.1069981523397086 1.0365103361254855 1.0716629446560113 1.005771289060511 1.0 16.528510849992216 -7.353418559709506 0.5822270088504873 1.0001445269284832 1.138902306609201 0.7544215887141819 0.026697980649811714 0.4128027523347377 0.2877879338940204 0.025051401406651734 0.01811755482007254 4.431813134751397e-08 7.353418559709506 0.13875777968071779 LDNVPHTPS(ph)SYIETLPK ddPTM_PC-9_Lapatinib_30min_R1 1 LDNVPHTPSSYIETLPK 17 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;A8MXH2;E9PNW0;E9PJJ2;E9PKI2;E9PP22 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 LDNVPHTPS(0.937)S(0.063)YIETLPK 171.47 6.436799999999999e-06 2990000.0 35994.0 29426.0 33369.0 29627.0 29054.0 27036.0 24838.0 22863.0 27128.0 20620.0 True False 35480.718959508806 29357.86590492804 30625.52962806497 31805.86841277474 27345.10084236175 25879.733303994206 26123.99010673261 23925.298445484994 24072.558969495647 24184.139525577077 1.4671069409761095 1.213930554522283 1.2663477067553095 1.3151540239476762 1.1307038984555 1.0701118092964967 1.0802116849807268 0.9892970729920603 0.9953862093805974 1.0 14.561773586993464 -6.323189885871338 0.5689013374431338 0.9761794328707948 1.3914721996217998 0.8359689886191806 0.06131984747310586 0.41168352190164764 0.276980701449411 0.04690353527390523 0.08919287406537843 4.7512744132154803e-07 6.323189885871338 0.415292766751005 LDNVPHTPSS(ph)YIETLPK ddPTM_PC-9_AZD4547_30min_R2 3 LDNVPHTPSSYIETLPK 17 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;A8MXH2;E9PNW0;E9PJJ2;E9PKI2;E9PP22 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 LDNVPHT(0.136)PS(0.207)S(0.505)Y(0.149)IET(0.004)LPK;LDNVPHTPS(0.07)S(0.754)Y(0.175)IET(0.001)LPK;LDNVPHTPS(0.337)S(0.535)Y(0.124)IET(0.004)LPK 91.932 0.0012083 32679500.0 88138.0 80256.0 143942.0 185188.0 159245.0 144305.0 131970.0 178741.0 125348.0 136766.0 True False 116164.05061571291 106197.18250838113 142033.2350299681 142495.76772607892 137136.58051878662 135281.58553783575 143715.07434023425 151120.68550956956 131973.63937698628 131977.86396833052 0.8801782899258598 0.8046590489891869 1.0761898303192001 1.0796944536113442 1.0390877408933819 1.0250323915705895 1.0889331742383723 1.1450456990714182 0.9999679901521572 1.0 17.009936447799596 -5.265201871040003 24.999293483604525 1.062130265848841 0.8424186597843564 0.7806787417679125 0.04536810520278571 119.76760884021144 795782.6143533825 0.01159915700773486 0.025681272209798534 5.429978737016103e-06 5.265201871040003 -0.2197116060644846 LDNVPHTPSS(ph)YIETLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LDNVPHTPSSYIETLPK 17 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;A8MXH2;E9PNW0;E9PJJ2;E9PKI2;E9PP22 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 LDNVPHTPS(0.183)S(0.815)Y(0.002)IETLPK;LDNVPHTPS(0.005)S(0.995)YIETLPK 169.85 8.7091e-06 11695200.0 81563.0 81894.0 76556.0 92922.0 101517.0 86560.0 87444.0 82297.0 83686.0 63648.0 True False 95370.00495731906 90023.89510140906 78381.38538024682 87715.88159718868 81625.4725958819 82020.64121982895 79160.67128026397 80136.79095087932 84909.74943164262 75186.87856270921 1.2684394774784569 1.1973351843077926 1.0424875573850727 1.1666381591307813 1.0856345436365284 1.0908903626238462 1.0528522102994398 1.0658347903622793 1.1293160595944156 1.0 16.19819328767254 -1.5228787664086336 0.618201226668331 1.0732063440053357 15.653795640931396 0.6495276558103081 0.04552864445121858 113.07238336197904 0.8210709365247931 0.019249603788232088 2238.5300854439 0.02999999854050905 1.5228787664086336 14.58058929692606 LDNVPHTPSS(ph)YIETLPK ddPTM_PC-9_Lapatinib_30min_R1 3 LDNVPHTPSSYIETLPK 17 0 E9PNJ7;C9J6D1;Q99733;Q99733-2;E9PS34;A8MXH2;E9PNW0;E9PJJ2;E9PKI2;E9PP22 E9PNJ7 NAP1L4 Nucleosome assembly protein 1-like 4 1 LDNVPHTPS(0.034)S(0.96)Y(0.005)IET(0.001)LPK;LDNVPHTPS(0.007)S(0.992)YIETLPK;LDNVPHTPS(0.184)S(0.799)Y(0.003)IET(0.014)LPK 130.73 1.5608e-05 13763500.0 189509.0 144009.0 176993.0 156012.0 163798.0 154149.0 148178.0 141200.0 168887.0 119467.0 True False 186806.5669083057 143675.55600838666 162441.31875273748 167485.64292077578 154163.72367925834 147556.40660886985 155849.93179947784 147760.66747594252 149865.16760104755 140116.7117702284 1.3332211736073427 1.0253991418525026 1.159328653238154 1.1953295278255498 1.1002522235325152 1.0530964133018015 1.1122865347785902 1.0545542041997755 1.0695738267595463 1.0 17.096269511220335 -1.5228787452803376 0.1761428266023176 1.0044682108568992 1.8928744255294818 0.4542037321960889 0.06884753975902656 59.916144644253826 0.6650340652427112 0.16201761407181392 14.159283533603224 0.029999999999999995 1.5228787452803376 0.8884062146725826 LDPFADGGKT(ph)PDPK ddPTM_PC-9_AZD4547_30min_R2 1 LDPFADGGKTPDPK 14 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 LDPFADGGKT(1)PDPK 114.54 0.0017724 6726000.0 53624.0 59923.0 36798.0 43106.0 50145.0 50436.0 55755.0 48934.0 47884.0 57983.0 True False 70675.3165515099 79291.93789186738 36310.034476613946 33168.57768106114 43183.232315705674 47282.228946926974 60717.086988253104 41372.37469145452 50415.05048287651 55953.03281865167 1.2631186012843012 1.4171159970695242 0.6489377366602758 0.5927932054829486 0.7717764371355176 0.8450342468507922 1.0851438059674463 0.7394125502641787 0.9010244475268354 1.0 15.771928711177319 -5.255584000344804 24.999544415370707 0.8138045521828838 1.3401173505094262 0.6682462841024861 0.14562335737199925 278.3685850836121 1188486.0337420856 0.03946801773013266 0.09872646989546988 5.551572293658864e-06 5.255584000344804 0.5263127983265423 LDPHLVLDQLR ddPTM_PC-9_AZD4547_30min_R2 1 LDPHLVLDQLR 11 0 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580 P35579 MYH9;MYH10 Myosin-9;Myosin-10 0 120.86 0.00069263 9644800.0 64113.0 61329.0 73842.0 101710.0 95784.0 86735.0 75335.0 97847.0 72201.0 73092.0 False True 84499.60036675677 81152.39989603893 72862.80683249426 78262.33090383546 82486.04495218954 81311.44673867308 82039.66905676718 82726.99445037708 76017.39745873719 70533.07132747334 1.198013907184605 1.1505581476703575 1.0330303992322174 1.1095834823422965 1.1694662291001128 1.152813073475243 1.1631376248436796 1.1728823499871341 1.0777553852121515 1.0 16.106012242066598 -8.542296105903764 4.221408353522975 1.0001404073722622 1.1405559754616803 0.525149933111237 0.04302483094916424 0.16139753125878117 9.669400726429853 0.04500141709866986 0.011767763711312757 2.8688239249811668e-09 8.542296105903764 0.14041556808941813 LDPHLVLDQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LDPHLVLDQLR 11 0 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580 P35579 MYH9;MYH10 Myosin-9;Myosin-10 0 ; 121.29 0.00065689 12361000.0 88008.0 86400.0 97587.0 99446.0 109789.0 98162.0 97825.0 89154.0 85678.0 74176.0 False True 102906.01616276705 94977.22100229225 99913.84418075829 93874.36302828185 88276.63357693108 93014.21191567525 88558.30780833232 86813.80196647126 86930.87866314886 87623.52162310708 1.1744108688691397 1.0839238054231084 1.1402628236116241 1.0713374820982584 1.007453614528679 1.061521041299333 1.0106682106346514 0.9907591062121579 0.992095239415993 1.0 16.41903057784527 -5.70282907132361 0.5051452594835855 0.9897384725534638 1.1899274307061614 0.8106410581519075 0.02681718233842768 0.8237867456784711 0.30817212955540546 0.019695618073379065 0.08901705072211076 1.9823070643894626e-06 5.70282907132361 0.20018895815269755 LDPHLVLDQLR ddPTM_PC-9_Lapatinib_30min_R1 1 LDPHLVLDQLR 11 0 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580 P35579 MYH9;MYH10 Myosin-9;Myosin-10 0 65.232 0.037943 9496600.0 40018.0 43758.0 47144.0 42712.0 48456.0 43627.0 44948.0 41688.0 43503.0 38932.0 False True 39447.33598159759 43656.681039483534 43268.002301102664 45853.18296305515 45605.91334816139 41761.17490950418 47275.18750774693 43624.97666952625 38603.234033101224 45661.34432637083 0.8639109637167547 0.9560971470187412 0.9475849416924429 1.0042013357143653 0.9987860414749675 0.9145848753600059 1.035343750938232 0.9554028098189716 0.8454248249280446 1.0 15.478685714461129 -4.736509182044835 3.5316635255984243 0.9642211530666107 0.8459782046885421 0.24920416377876886 0.05106353661789373 0.5254384693339164 9.930535498269952 0.012811961566570985 0.17672131716936543 1.8343863833044985e-05 4.736509182044835 -0.11824294837806859 LDPHNHVLYSNR ddPTM_PC-9_AZD4547_30min_R2 2 LDPHNHVLYSNR 12 0 P31948-2;P31948;P31948-3;F5H783;F5GXD8 P31948-2 STIP1 Stress-induced-phosphoprotein 1 0 ; 58.781000000000006 0.028116000000000002 40404000.0 62996.0 64768.0 140575.0 194766.0 153053.0 139216.0 114169.0 156404.0 103560.0 123684.0 False True 83027.41760179993 85702.9893927287 138710.88364992657 149865.7078047035 131804.23283708617 130510.8015123201 124329.81982534064 132235.3556063727 109033.97017806974 119353.86080647969 0.6956408200017975 0.7180579565137613 1.1621817904561325 1.2556418937104659 1.1043147825003625 1.0934778366652946 1.0416908090382513 1.1079269217841143 0.9135353430657546 1.0 16.864885709279406 -5.254127198995619 24.607787030132716 1.0942628723850472 0.7068493069888799 0.7511357990624091 0.08689508281064617 214.48993838238317 721820.1620067742 0.023228467728640678 0.05881871658795645 5.570225806379223e-06 5.254127198995619 -0.3874135653961672 LDPHNHVLYSNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LDPHNHVLYSNR 12 0 P31948-2;P31948;P31948-3;F5H783;F5GXD8 P31948-2 STIP1 Stress-induced-phosphoprotein 1 0 ;; 62.088 0.022347 24565900.0 143794.0 168049.0 226994.0 259053.0 284628.0 254973.0 261417.0 243798.0 235783.0 195001.0 False True 168135.4841390432 184731.79412285006 232406.39783953928 244539.10027115757 228857.18661919353 241601.76702568622 236653.68926481795 237398.5608253334 239230.88031738822 230353.1376729337 0.7299031644959398 0.8019504139993135 1.0089135324456526 1.0615835440382226 0.9935058360009656 1.048832108242102 1.027351707276634 1.0305853144592418 1.038539707920365 1.0 17.813487723667635 -5.20334020405532 3.003591807955566 1.0304266649670273 0.740435020817642 0.9652963239096791 0.019972430829695912 0.039106638293747775 0.6853349494670781 0.00507180121568383 0.016647417016304917 6.261231996679391e-06 5.20334020405532 -0.2899916441493853 LDPHNHVLYSNR ddPTM_PC-9_Lapatinib_30min_R1 3 LDPHNHVLYSNR 12 0 P31948-2;P31948;P31948-3;F5H783;F5GXD8 P31948-2 STIP1 Stress-induced-phosphoprotein 1 0 ;; 80.52199999999999 0.0059738 25124900.0 193037.0 176787.0 236830.0 179503.0 215167.0 208878.0 176294.0 173618.0 245196.0 164347.0 False True 190284.2569813495 176377.66056326084 217358.75159023673 192704.24942445444 202511.30009459832 199944.7748584002 185421.6407068333 181684.92610367035 217579.4444516536 192754.159971388 0.9871862532543778 0.9150394501962601 1.1276475258562564 0.99974106630466 1.050619608545199 1.037304589888382 0.9619592165188906 0.9425733075262255 1.1287924705954497 1.0 17.55640247079154 -5.215607123961847 24.999842865555614 1.0263612576078622 0.951112851761109 0.21533649869112204 0.060525600060143556 687.7267984682053 375127.7840696178 0.015089866083442625 0.03992367517689383 6.0868538766499505e-06 5.215607123961847 -0.07524840584675319 LDPITGR ddPTM_PC-9_Lapatinib_30min_R1 1 LDPITGR 7 0 Q14103-3;Q14103;D6RAF8;D6RD83;H0YA96;H0Y8G5;Q14103-4;Q14103-2;D6RF44;D6RBQ9 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 0 102.77 0.012235 0.0 8471.6 14277.0 10758.0 17087.0 19056.0 18445.0 16137.0 18556.0 20148.0 14970.0 False True 8350.793430498827 14243.942483676261 9873.518767080915 18343.63498056105 17935.163545537464 17656.150347395072 16972.494901052596 19418.17950200846 17878.720072154174 17557.544553728854 0.4756242198300612 0.8112718973935992 0.5623519129834125 1.0447722302185614 1.0215075058276535 1.0056161494202376 0.9666781621492736 1.1059735285071195 1.0182927354928517 1.0 14.099803475683773 -5.766233951788813 24.999993568137352 1.0245123885957057 0.6359015674393698 0.8254710260852081 0.08558622367303864 43.361330631422746 226097.3328104372 0.022454016175279916 0.034547575323761306 1.7130342578025565e-06 5.766233951788813 -0.38861082115633594 LDPPPS(ph)PHANR ddPTM_PC-9_AZD4547_30min_R2 4 LDPPPSPHANR 11 0 E7EUN2;A0A087X1U1;F5GXM9;Q9UPQ3-2;Q9UPQ3;H7C0A7;H7C211 E7EUN2 AGAP1 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 1 LDPPPS(1)PHANR;LDPPPS(1)PHANR;LDPPPS(1)PHANR;LDPPPS(1)PHANR 94.71700000000001 0.0063966 86934000.0 254998.0 264319.0 315262.0 394027.0 349436.0 343743.0 330885.0 458791.0 335286.0 312992.0 True False 336082.05971210497 349754.9477102372 311081.41989146854 303190.1628064653 300922.8431044152 322248.69587008364 360333.123990819 387895.39291836077 353008.53346006444 302034.2453473506 1.1127283243183173 1.1579976545639916 1.0299541349482186 1.00382710727979 0.9963202773855752 1.066927677354883 1.1930207568894133 1.2842762001119001 1.1687698957914243 1.0 18.204352609390575 -7.245875842116101 7.680265878783758 1.1853090978453316 1.0585240182506404 0.25109641680561023 0.08064666664107986 0.20296380742046724 73.26735652582884 0.032286866929292536 0.02410627553487671 5.6770688057793845e-08 7.245875842116101 -0.1267850795946912 LDPPPS(ph)PHANR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LDPPPSPHANR 11 0 E7EUN2;A0A087X1U1;F5GXM9;Q9UPQ3-2;Q9UPQ3;H7C0A7;H7C211 E7EUN2 AGAP1 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 1 LDPPPS(1)PHANR;LDPPPS(1)PHANR;LDPPPS(1)PHANR;LDPPPS(1)PHANR;LDPPPS(1)PHANR 117.03 0.0012025 100613600.0 322848.9 416421.6 425305.0 409977.6 497988.0 336617.0 376139.2 312321.9 314020.0 307466.0 True False 377500.84221356566 457761.18441352004 435445.88417819474 387007.8842373133 400410.8262367694 318964.21193963883 340508.5719640157 304123.78105740726 318611.94843252585 363207.1519004834 1.039354099274451 1.2603308663342176 1.1988912715504685 1.0655293603451705 1.10243100704823 0.8781881366340306 0.937505140475078 0.8373287240245075 0.8772182672213008 1.0 18.470433085407528 -6.580606347210241 1.6730113754313989 0.892386143350624 1.1627670464842172 0.6942557970812999 0.07420007554454425 0.1892540290435034 1.0837628100950418 0.02873475724360451 0.03010428638116025 2.6265982634005975e-07 6.580606347210241 0.2703809031335932 LDPPPS(ph)PHANR ddPTM_PC-9_Lapatinib_30min_R1 3 LDPPPSPHANR 11 0 E7EUN2;A0A087X1U1;F5GXM9;Q9UPQ3-2;Q9UPQ3;H7C0A7;H7C211 E7EUN2 AGAP1 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 1 LDPPPS(1)PHANR;LDPPPS(1)PHANR;LDPPPS(1)PHANR 67.964 0.021759 47911100.0 161963.0 273270.0 289707.0 259598.0 266483.0 280001.0 249151.0 240345.0 289124.0 242038.0 True False 159653.37791962342 272637.2601046581 265888.4087613605 278689.702913542 250808.9938657359 268026.0099442109 262050.8196747942 251512.3061225598 256559.81050930667 283873.945804638 0.5624094083981095 0.9604166360948356 0.9366425228201284 0.9817375177690179 0.8835224139884349 0.9441726298075497 0.9231238849060758 0.8859999652650424 0.9037807600908577 1.0 18.114890917781146 -4.758728884448454 24.99982153246866 0.9316683888286018 0.5624089165127973 0.9030273417465626 0.0366579792863323 20.65929690198276 190510.8681910675 0.008968098439749175 0.060145093137005765 1.7428945647635582e-05 4.758728884448454 -0.36925947231580447 LDPPPS(ph)PHSNR ddPTM_PC-9_Lapatinib_30min_R1 1 LDPPPSPHSNR 11 0 Q96P47;Q96P47-2;Q96P47-4;H0Y873 Q96P47 AGAP3 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 1 LDPPPS(0.994)PHS(0.006)NR 110.98 0.0034388000000000005 0.0 51284.0 52482.0 54175.0 52372.0 43410.0 39203.0 45170.0 38730.0 40550.0 31257.0 True False 50552.680755666246 52360.48115348446 49720.94062154757 56223.61158787048 40856.709147343696 37526.37907665649 47508.6815814926 40529.5371908163 35982.8319895698 36659.73080266551 1.3789703210802244 1.4282832963322623 1.3562822075587195 1.5336613323898847 1.1144847016817983 1.023640333821763 1.2959364551045278 1.1055601419710759 0.981535630560427 1.0 15.161908571562398 -6.277271878568523 23.419479148577167 1.0994303707716009 1.419725478916537 0.7575112109133936 0.09335373539760951 179.51597421662657 265539.71207721526 0.029063324024559776 0.03308782146985422 5.281145361371922e-07 6.277271878568523 0.3202951081449361 LDPPPSPHS(ph)NR ddPTM_PC-9_Lapatinib_30min_R1 1 LDPPPSPHSNR 11 0 Q96P47;Q96P47-2;Q96P47-4;H0Y873 Q96P47 AGAP3 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 1 LDPPPS(0.498)PHS(0.502)NR 98.368 0.0050051 10201000.0 45870.0 54047.0 57557.0 38640.0 45298.0 51475.0 39550.0 42549.0 48554.0 31506.0 True False 45215.885388472205 53921.85749213781 52824.88563644504 41481.71449926135 42633.660699294545 49273.53424408574 41597.70548036377 44525.98187276125 43085.33722371325 36951.77012089385 1.2236459915327718 1.4592496466535567 1.4295630618944548 1.1225907274143303 1.1537650445380951 1.3334553143970964 1.1257297104920811 1.2049756135385965 1.1659884515072596 1.0 15.173355855787388 -1.5228787452860064 0.05620490451277739 0.6111309381238816 2.461046462816185 0.4585131444707252 0.10097944333035826 354.4821697290816 1.500340526826457 10.608297392857986 54.75094570603005 0.02999999999960841 1.5228787452860064 1.8499155246923034 LDPRCS(ph)HLGVFS(ph)EHLIK ddPTM_PC-9_AZD4547_30min_R2 1 LDPRCSHLGVFSEHLIK 17 1 O96001-2 O96001-2 2 LDPRCS(1)HLGVFS(1)EHLIK 51.888000000000005 0.031591 42876000.0 30270.0 21429.0 37734.0 45661.0 30157.0 40652.0 28755.0 30882.0 33687.0 35296.0 True False 39895.23034488673 28355.505183065416 37233.622505042375 35134.561905417664 25970.221097711335 38110.024013610804 31314.139294183806 26109.896497762278 35467.62604662647 34060.297783266265 1.1713118481450022 0.8325090216033402 1.093167850204033 1.0315400684100648 0.762477805184382 1.1188987323632313 0.919373620672464 0.7665786325153623 1.0413187304560685 1.0 15.055803427853148 -4.740956614510484 24.94593888702058 0.9496759493349082 1.1713126650459067 0.22408978761147125 0.12250429784646123 2310.5913872095966 2813918.1138134664 0.02960837777347303 1.248308517237258 1.8156970396349935e-05 4.740956614510484 0.22163671571099852 LDPSIFESLQK ddPTM_PC-9_Lapatinib_30min_R1 2 LDPSIFESLQK 11 0 Q9Y265;E7ETR0;Q9Y265-2 Q9Y265 RUVBL1 RuvB-like 1 0 ; 123.51 0.0025949000000000002 4387000.0 26382.0 24440.0 31319.0 19442.2 21583.4 23851.0 25234.0 22729.0 20306.0 21566.0 False True 26005.787842133723 24383.410681589125 28744.07271483614 20872.044245277917 20313.90684659707 22830.948329396564 26540.493049089742 23785.07231629394 18018.92444834043 25293.654365111302 1.0281546298823747 0.964012962682936 1.1364143867832779 0.8251889562493463 0.8031226549302806 0.9026354199292111 1.0492945252584087 0.9403572917127302 0.7123891308167299 1.0 14.626487868648379 -5.77013512020571 24.999934714051165 0.8914322441704176 1.0349758993135516 0.32963088542967056 0.09941926880681398 234.4464552643828 674026.221907564 0.028939903844186095 0.04367419603267074 1.6977153672811243e-06 5.77013512020571 0.14354365514313405 LDQEDALLGSYPVDDGCR ddPTM_PC-9_Lapatinib_30min_R1 2 LDQEDALLGSYPVDDGCR 18 0 K7EK42;A0A494C0X0;Q99426;K7EP07;Q99426-2;K7EL99;K7EQH0;K7ER04 K7EK42 TBCB Tubulin-folding cofactor B 0 ; 142.57 0.00086364 4864300.0 20924.2 23237.8 26746.0 21123.5 25427.0 25522.0 20210.5 25304.0 26334.0 22864.5 False True 20625.817070971672 23183.994301826162 24547.04712254566 22676.99265593032 23931.433851405414 24430.483554687817 21256.900799264018 26479.71621679361 23367.98761068633 26816.59835996882 0.7691436771399538 0.8645389691346789 0.9153676686745217 0.845632706711303 0.892411242103312 0.9110209739038737 0.792677002277657 0.9874375512265531 0.8714001416961783 1.0 14.710838624978019 -14.52287874387177 0.037449756806149585 1.6115404662680324 0.5065869776011465 0.40647540461665976 0.05418764431516381 999.8561898992715 2.792703881025622 71.63506318945495 23.160376581356545 3.0000000097300406e-15 14.52287874387177 -1.104953488666886 LDQLIYIPLPDEK ddPTM_PC-9_Lapatinib_30min_R1 1 LDQLIYIPLPDEK 13 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 143.31 0.00039324 26550000.0 190650.0 179130.0 218420.0 189360.0 186540.0 152210.0 200030.0 175850.0 185170.0 203670.0 False True 187931.29603907172 178715.2354907141 200462.35072558222 203286.16608644236 175568.08395175065 145700.33311883983 210386.57464569306 184020.6329719868 164314.20467345606 238874.0881267834 0.7867378898766383 0.7481566414012233 0.8391967178088651 0.8510180726615579 0.7349817024045202 0.6099461614334192 0.8807425547723264 0.770366658079369 0.6878695213950775 1.0 17.865890840334558 -10.653928659211715 4.964806075390875 1.0000111837590537 0.7694545961196668 0.4559094702064517 0.0761197520461293 111123008.77338538 6.708875952981203 14207.252366908886 0.01884776528581149 2.2185608289419783e-11 10.653928659211715 -0.2305565876393869 LDQPGNLPGS(ph)NRR ddPTM_PC-9_AZD4547_30min_R2 2 LDQPGNLPGSNRR 13 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 LDQPGNLPGS(1)NRR;LDQPGNLPGS(1)NRR 78.501 0.006843000000000001 46510000.0 67077.0 66385.0 75130.0 98437.0 92669.0 76185.0 60383.0 93823.0 76488.0 88951.0 True False 88406.0907117269 87842.65302057021 74133.72711093014 75743.87048648953 79803.50893337569 71421.13990644833 65756.97002262913 79324.8111880561 80530.99952665312 85836.8525645774 1.029931644397336 1.0233675909130497 0.8636584974403309 0.882416680288986 0.9297114997703037 0.8320568354101318 0.7660692122088048 0.9241346673141106 0.9381867708402688 1.0 16.389309556381015 -5.25547577311479 23.955996664706515 0.8836818334231883 1.0266496580902986 0.4334083615975741 0.06097361286129245 236.06219437165797 948255.48826863 0.015928284903269255 0.03976012429960553 5.552955931229977e-06 5.25547577311479 0.14296782466711033 LDQPGNLPGS(ph)NRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LDQPGNLPGSNRR 13 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 LDQPGNLPGS(1)NRR;LDQPGNLPGS(1)NRR;LDQPGNLPGS(1)NRR;LDQPGNLPGS(1)NRR 90.259 0.004340699999999999 32585200.0 185377.0 177562.0 208003.0 187746.0 216173.0 160709.0 184465.0 138849.0 129025.0 116953.0 True False 216757.66473735645 195189.18189362332 212962.58037577049 177227.20030074476 173815.4524608651 152281.13712797462 166991.13978905242 135204.3608726763 130911.74653368167 138155.65310056135 1.5689380772539356 1.4128208112595158 1.5414684495086013 1.2828081683472181 1.2581132118737663 1.1022432575895504 1.2087173853646234 0.9786379191755776 0.947567063639394 1.0 17.075935070487212 -6.388112536361349 0.5468511581139919 0.9605014152375918 1.5868562887695155 0.8881818074109038 0.07183754280093171 0.32522836482081396 0.2026672355586238 0.05640356177089796 0.10213308620648355 4.091546239853446e-07 6.388112536361349 0.6263548735319237 LDQPGNLPGS(ph)NRR ddPTM_PC-9_Lapatinib_30min_R1 2 LDQPGNLPGSNRR 13 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 LDQPGNLPGS(1)NRR;LDQPGNLPGS(1)NRR 115.58 0.00013164 35515000.0 104005.0 158075.0 193719.0 127064.0 124012.0 137424.0 125907.0 96713.0 124218.0 83754.0 True False 102521.86962781895 157708.98704959886 177792.17159696514 136408.71043307797 116717.85797697288 131546.69587099052 132425.84839231762 101206.6390481645 110227.26076647048 98230.76730481017 1.0436838929466312 1.6054948095867734 1.8099438340461687 1.3886556541882809 1.188200613508365 1.339159811943655 1.3481096811694455 1.0302947011919412 1.1221256210331247 1.0 16.583887347937555 -7.406269114506161 0.6932291969987348 1.0066844761284142 1.4779617991566738 0.37025298781842664 0.20014689939395874 0.7814171272995438 0.7319227097349075 0.18645949952823726 0.1118708998698557 3.9240170477967676e-08 7.406269114506161 0.47127732302825964 LDQPVS(ph)APPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 LDQPVSAPPSPR 12 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 2 LDQPVS(1)APPS(1)PR;LDQPVS(1)APPS(1)PR 112.57 0.011356 158504000.0 743950.0 758930.0 933880.0 1249210.0 1121800.0 991800.0 805000.0 1018910.0 827400.0 879380.0 True False 980510.6248787099 1004239.280814962 921496.1410136485 961223.9346021059 966057.433677508 929782.5892133034 876643.4405083604 861460.8717225216 871134.6748294214 848593.1738624383 1.1554542919734305 1.1834166379680953 1.0859103860326693 1.1327264515068156 1.1384223482265619 1.0956753104450807 1.0330550227245514 1.0151635651292303 1.0265633776717573 1.0 19.6947135479813 -7.151125260397865 1.7660932989944742 1.0138628662385936 1.1397578184691195 0.855815603540956 0.023433316212644297 0.13941785404190676 0.8563820282142053 0.01248286805615361 0.008444711815302253 7.06113865604972e-08 7.151125260397865 0.12589495223052594 LDQPVS(ph)APPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LDQPVSAPPSPR 12 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 2 LDQPVS(1)APPS(1)PR 118.71 0.0069336 22984000.0 94159.0 100890.0 104470.0 121010.0 144210.0 127250.0 132820.0 126530.0 109620.0 99692.0 True False 110098.2589749789 110905.69244121833 106960.96100468111 114230.20201971338 115953.0857201467 120576.78598917754 120238.32806647284 123208.72156961652 111222.9851193348 117765.37043856236 0.9348950252945254 0.9417513147388036 0.9082547832724913 0.9699812567507419 0.9846110557656581 1.0238730243037097 1.0209990221972818 1.0462220015169394 0.9444455930052826 1.0 16.845555843475076 -6.161312116832496 2.0374929275562548 1.009850819423164 0.9300371612055501 0.6051246949666471 0.026925167013838115 0.20961488990114863 1.711828574656208 0.008786958790777677 0.012282775219127596 6.89743923568555e-07 6.161312116832496 -0.07981365821761377 LDQPVS(ph)APPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 LDQPVSAPPSPR 12 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 2 LDQPVS(1)APPS(1)PR 121.45 0.0054082999999999996 80079000.0 552410.0 580720.0 637870.0 583780.0 693620.0 710070.0 645350.0 660830.0 738550.0 561950.0 True False 544532.5321004118 579375.3785193294 585426.7908494049 626713.128632992 652822.6353093884 679701.9613540148 678763.0652781989 691534.5742785204 655366.7217237182 659082.3087486922 0.8261980709727135 0.8790637691661133 0.8882453421650374 0.950887499655157 0.9905024405052107 1.0312853983965529 1.0298608478307845 1.0492385626181362 0.9943624840544906 1.0 19.33009912025966 -5.84686238293395 1.0739005538361255 1.0262063988929029 0.8387494586761526 0.9332935507274546 0.018474416079243043 0.1254322832184612 0.28499617807524186 0.00697759016710359 0.01765139562848301 1.4227795589795018e-06 5.84686238293395 -0.1874569402167503 LDQPVSAPPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 LDQPVSAPPSPR 12 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 LDQPVS(0.024)APPS(0.976)PR;LDQPVSAPPS(1)PR;LDQPVSAPPS(1)PR;LDQPVS(0.006)APPS(0.994)PR 103.11 0.0021982 477470000.0 146709.0 168979.0 159773.0 149478.0 168382.0 203903.0 157322.0 199571.0 163916.0 148337.0 True False 193359.41026323073 223598.157185553 157654.30562617647 115018.15651207864 145005.06578488718 191152.9131764068 171323.35322690287 168731.8876353513 172580.26511885377 143143.7667802689 1.3508056593204283 1.5620530478898507 1.1013703856779304 0.8035149493350686 1.0130030042277387 1.3353911069689381 1.1968621273596265 1.1787581913668734 1.2056428931604897 1.0 17.127105323740302 -5.271882665053792 24.251089332236212 1.1082555993897412 1.4564293503915373 0.48570679086924606 0.14488475074449833 377.5389175942134 876711.7781027033 0.04162610795001864 0.08826559207076055 5.3470880413848885e-06 5.271882665053792 0.34817375100179615 LDQPVSAPPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LDQPVSAPPSPR 12 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 LDQPVSAPPS(1)PR;LDQPVSAPPS(1)PR;LDQPVSAPPS(1)PR;LDQPVSAPPS(1)PR 148.18 8.5059e-05 319989000.0 242163.0 223553.0 338086.0 317691.0 421824.0 363310.0 371446.0 324010.0 373678.0 300392.0 True False 283156.4129627313 245745.86442969294 346147.25243829563 299891.80323811906 339170.6152889205 344257.3840292979 336259.9458438427 315505.08081697166 379142.33382067754 354850.69169823575 0.7979593096116236 0.692533141907117 0.9754729539393387 0.8451210896698671 0.9558121858681636 0.9701471409898044 0.9476096671379675 0.8891206589087799 1.068455952575962 1.0 18.436852592975953 -5.343163270274646 0.9610085534277062 0.965752612155436 0.7094763556720751 0.5560862050545266 0.06954060894100354 0.7219597162075426 0.9360926916402768 0.024336649700281956 0.16026207691297156 4.537709922336126e-06 5.343163270274646 -0.25627625648336083 LDQPVSAPPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 LDQPVSAPPSPR 12 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 LDQPVSAPPS(1)PR 187.08 0.00034155 100420000.0 187570.0 181700.0 224380.0 136970.0 234800.0 245770.0 220590.0 226350.0 304170.0 286930.0 True False 184895.21740387447 181279.28481361485 205932.34253184724 147043.23071852536 220989.5256345613 235258.99001785248 232011.07084484032 236867.04733130118 269911.1715479021 336525.4681898069 0.549424144325356 0.5386792440665139 0.6119368725332176 0.4369453269301749 0.6566799440864871 0.6990822753574236 0.6894309429026084 0.7038606872918859 0.8020527331847198 1.0 18.360356166317736 -8.335774914974625 0.3364295222323388 1.039693993474564 0.5042624546752608 0.8628441189151752 0.05472356814060733 0.5397416180991523 0.19049348670132812 0.10636908726722773 0.06969445498778903 4.615567270129131e-09 8.335774914974625 -0.5354315387993032 LDRETEELHHDR ddPTM_PC-9_AZD4547_30min_R2 1 LDRETEELHHDR 12 1 O60869-2;O60869-3;O60869 O60869-2 EDF1 Endothelial differentiation-related factor 1 0 86.911 0.0039944 10407000.0 33413.0 33431.0 54889.0 84274.0 64503.0 44263.0 36964.0 65321.0 36311.0 47020.0 False True 44037.638966425504 44236.916971163395 54161.135996164514 64845.931320320815 55547.871852826065 41495.22761277315 40253.72439124363 55227.14037725303 38230.32532962426 45373.844111774146 0.9705512025373687 0.9749431161748157 1.1936642587025184 1.4291478403412115 1.2242267090262215 0.9145186709451729 0.8871570213906147 1.2171580666871915 0.8425630686138802 1.0 15.46957327080215 -6.7601066980448214 24.999996647140847 0.9805315912163576 1.1652974859208445 0.26693133704307614 0.15379799241828937 56.6272843886039 1062291.0908173954 0.05685262477495185 0.053911196690703524 1.7373739359768504e-07 6.7601066980448214 0.1847658947044869 LDRETEELHHDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LDRETEELHHDR 12 1 O60869-2;O60869-3;O60869 O60869-2 EDF1 Endothelial differentiation-related factor 1 0 ;; 98.902 0.001583 23605200.0 113871.0 94240.0 173483.0 163480.0 160037.0 157200.0 145739.0 166894.0 147541.0 103469.0 False True 133147.11124523266 103595.52438953731 177619.49265794136 154320.7456093112 128678.89868521686 148956.15526521602 131933.5468610124 162513.20933880983 149698.5080048512 122227.1106398468 1.0893418861676494 0.8475658456395232 1.4531922723863875 1.2625737841748645 1.0527852455285542 1.2186834368042025 1.079413120136387 1.3296003520664876 1.2247569890280017 1.0 16.899204792716787 -5.241272573840042 24.99951862468537 1.2073597166768375 0.9684538766853613 0.3139388741125376 0.13832767093096657 940.4867483194438 1165858.5045546126 0.03426519624123928 0.09040447745384449 5.737562457244492e-06 5.241272573840042 -0.2389058399914762 LDRETEELHHDR ddPTM_PC-9_Lapatinib_30min_R1 2 LDRETEELHHDR 12 1 O60869-2;O60869-3;O60869 O60869-2 EDF1 Endothelial differentiation-related factor 1 0 ; 105.36 0.00081119 19566400.0 91420.0 80333.0 111135.0 84357.0 93988.0 93093.0 69749.0 67050.0 102890.0 69266.0 False True 90116.33403562513 80146.99387414467 101997.90929350596 90560.89518670263 88459.81062751763 89111.62940038211 73360.26193552198 70165.3877780591 91301.44472026711 81238.53580885658 1.109280628194196 0.986563741901009 1.2555360369060984 1.1147529221819104 1.0888897706828657 1.0969132876797516 0.9030229460083927 0.863695868954961 1.1238686641901967 1.0 16.309876617209888 -7.1877121051871535 6.8890274780103 0.9615770672215685 1.1099008151865186 0.36087864378965995 0.0882214218076599 0.2693743945224361 21.440366738378092 0.033901266029250685 0.026158885073030193 6.490645573582388e-08 7.1877121051871535 0.14832374796495007 LDRPAGGPSAES(ph)PRPSSAYNGDLNGLLVPDPLCSGDSTSANK ddPTM_PC-9_AZD4547_30min_R2 2 LDRPAGGPSAESPRPSSAYNGDLNGLLVPDPLCSGDSTSANK 42 2 Q6P2E9 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 LDRPAGGPS(0.215)AES(0.26)PRPS(0.208)S(0.167)AY(0.15)NGDLNGLLVPDPLCSGDSTSANK;LDRPAGGPS(0.064)AES(0.549)PRPS(0.237)S(0.078)AY(0.071)NGDLNGLLVPDPLCSGDSTSANK 68.249 4.8011999999999995e-09 10201200.0 14614.400000000001 18572.9 24890.0 26998.0 30410.0 29804.0 25243.0 34528.0 30562.0 27133.0 True False 19261.475201596066 24576.226712145035 24559.94233716292 20774.028214941987 26188.09641480923 27940.351168494937 27489.578097829293 29192.49097450732 32177.444926440407 26183.081928642452 0.7356458362728249 0.9386300199160424 0.9380080772804698 0.7934141699421816 1.0001915162691866 1.067114682856725 1.0498984868453407 1.1149371588137142 1.228940313983456 1.0 14.676347301946413 -6.5611461003305775 2.345112707062471 1.1009264833304737 0.863265536524635 0.6634065718160986 0.08018354275892468 0.18919723484388384 2.1048276077813663 0.029070070514281326 0.03046063941009183 2.746969893781119e-07 6.5611461003305775 -0.2376609468058387 LDRPAGGPSAES(ph)PRPSSAYNGDLNGLLVPDPLCSGDSTSANK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LDRPAGGPSAESPRPSSAYNGDLNGLLVPDPLCSGDSTSANK 42 2 Q6P2E9 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 LDRPAGGPS(0.165)AES(0.221)PRPS(0.221)S(0.221)AY(0.171)NGDLNGLLVPDPLCSGDSTSANK 60.64 2.5731e-06 7881100.0 15715.0 14277.0 17116.0 17503.0 20069.0 15926.0 16595.0 13583.0 13470.0 11029.0 True False 18375.23911460187 15694.326206594069 17524.11035279147 16522.363655491627 16136.623516521939 15090.812523879331 15023.001462604407 13226.46064237812 13666.97326726363 13028.470394484031 1.4103911325140321 1.204617712700848 1.3450627604151286 1.2681737115115856 1.2385662344026074 1.1582950313390934 1.153090194606791 1.0151967377519555 1.0490082759868669 1.0 13.669380094013505 -7.136988351923717 0.680689736321496 0.9951151818774991 1.3230151416283433 0.8403208552855967 0.05208150177379876 0.264498478001431 0.25038709372283957 0.04121258876220208 0.030333802407959205 7.294770750683624e-08 7.136988351923717 0.3278999597508442 LDRPAGGPSAES(ph)PRPSSAYNGDLNGLLVPDPLCSGDSTSANK ddPTM_PC-9_Lapatinib_30min_R1 3 LDRPAGGPSAESPRPSSAYNGDLNGLLVPDPLCSGDSTSANK 42 2 Q6P2E9 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 LDRPAGGPS(0.273)AES(0.293)PRPS(0.103)S(0.103)AY(0.226)NGDLNGLLVPDPLCS(0.001)GDSTSANK;LDRPAGGPS(0.085)AES(0.396)PRPS(0.177)S(0.177)AY(0.165)NGDLNGLLVPDPLCSGDSTSANK;LDRPAGGPS(0.119)AES(0.436)PRPS(0.153)S(0.153)AY(0.138)NGDLNGLLVPDPLCSGDSTSANK 52.35 0.00017948 15336100.0 32184.4 42385.2 45466.2 37801.0 42487.1 39440.3 37909.9 35555.5 46752.2 37110.4 True False 31725.44455410389 42287.05967353893 41728.14454060736 40581.011640439414 39988.09231085247 37753.53030882981 39872.68912743471 37207.53833173432 41486.47491350837 43524.88319350028 0.7289036115975507 0.9715605550402443 0.9587192768581345 0.9323634818277815 0.9187409448768844 0.8674010712673819 0.9160895148223863 0.8548567072844127 0.9531668293989514 1.0 15.409552805711087 -14.52287874510998 0.3385950199055865 2.0338381573243494 0.9003485806528309 0.17289686744093202 0.06707249990590079 744.4128067023307 6.298448460913398 555.7887243384254 0.05304316390090515 3.000000001176792e-15 14.52287874510998 -1.1334895766715185 LDRPAGGPSAESPRPSSAY(ph)NGDLNGLLVPDPLCSGDSTSANK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LDRPAGGPSAESPRPSSAYNGDLNGLLVPDPLCSGDSTSANK 42 2 Q6P2E9 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 LDRPAGGPS(0.007)AES(0.059)PRPS(0.207)S(0.207)AY(0.52)NGDLNGLLVPDPLCSGDSTSANK 72.73100000000001 6.652399999999999e-09 8926700.0 21617.0 22994.0 27601.0 25268.0 32390.0 30944.0 27180.0 23787.0 18148.0 19380.0 True False 25276.331144788342 25276.692357948046 28259.11251737539 23852.3158799613 26043.4120135605 29321.242166201297 24605.31363384079 23162.616454409817 18413.380167357103 22893.440588004418 1.1040861703431548 1.1041019483629906 1.2343759518690454 1.0418842807078683 1.1375927490429982 1.2807704483512576 1.07477570002009 1.0117577725100193 0.8043081203357981 1.0 14.482646677141242 -7.841970564761004 2.6246069024866294 0.9048170215620301 1.1469121625534555 0.5927872719914953 0.07999790181188696 0.18563948317952897 2.5223727146388186 0.052822909740191416 0.02179901525078715 1.4388960992169513e-08 7.841970564761004 0.24209514099142537 LDS(ph)LPEHEDSEK ddPTM_PC-9_Lapatinib_30min_R1 2 LDSLPEHEDSEK 12 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 LDS(0.999)LPEHEDS(0.001)EK;LDS(1)LPEHEDSEK 110.92 0.0020893 3588600.0 106165.0 30106.0 23448.0 18291.0 21421.6 22484.0 19849.5 21018.5 19019.0 20601.0 True False 104651.0676317236 30036.291406707143 21520.19595189748 19636.181156987295 20161.62360448601 21522.41173276392 20877.209985650585 21995.096241806674 16876.879941051247 24161.85540089298 4.331251300670225 1.2431285142778008 0.8906681873074256 0.8126934306651623 0.8344402062658182 0.8907598930489623 0.8640565734400927 0.9103231468305938 0.6984927134539307 1.0 14.560443623735992 -4.754776349118205 3.754087279038782 0.8656136222056895 4.801055845657436 0.9949035082049398 0.07400876365127444 0.019346695673669072 0.4653415911885279 0.02045547980024097 0.220782699063035 1.7588291341397664e-05 4.754776349118205 3.935442223451747 up LDS(ph)PPPSPITEASEAAEAAEAGNLAVSSR ddPTM_PC-9_AZD4547_30min_R2 3 LDSPPPSPITEASEAAEAAEAGNLAVSSR 29 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 LDS(0.777)PPPS(0.208)PIT(0.016)EASEAAEAAEAGNLAVSSR;LDS(0.733)PPPS(0.267)PIT(0.001)EASEAAEAAEAGNLAVSSR;LDS(0.96)PPPS(0.037)PIT(0.002)EASEAAEAAEAGNLAVSSR 146.63 1.0892e-13 8493800.0 18453.2 19969.6 26125.8 33724.8 28756.5 28759.0 23669.100000000002 25923.6 23535.600000000002 26641.3 True False 24320.93374959576 26424.382673187876 25779.35482170554 25950.068402965953 24764.156348321667 26960.695183691652 25775.604046877615 21917.703285065414 24779.643767120317 25708.596195980608 0.9460234064977144 1.0278423011412492 1.002752333312388 1.0093926640390851 0.9632636554536339 1.0487035145041022 1.0026064375661041 0.8525437607710421 0.9638660772537425 1.0 14.649963214287713 -7.6295945904358415 23.27522438771644 0.9304267422057433 1.00208331754483 0.28101750188647456 0.04423288589045434 6.225478073498696 1337.7376074436972 0.01950591020711325 0.011261739154367843 2.3464181512238727e-08 7.6295945904358415 0.07165657533908676 LDS(ph)PPPSPITEASEAAEAAEAGNLAVSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LDSPPPSPITEASEAAEAAEAGNLAVSSR 29 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 LDS(0.975)PPPS(0.023)PIT(0.002)EASEAAEAAEAGNLAVSSR;LDS(0.915)PPPS(0.08)PIT(0.005)EASEAAEAAEAGNLAVSSR;LDS(0.835)PPPS(0.15)PIT(0.015)EASEAAEAAEAGNLAVSSR;LDS(0.862)PPPS(0.131)PIT(0.008)EASEAAEAAEAGNLAVSSR 134.81 1.1521e-13 12668700.0 31609.5 36059.2 26608.0 31043.6 28963.699999999997 19509.5 17781.3 19703.800000000003 14033.899999999998 15894.33 True False 36960.364033917125 39638.91906904931 27242.43563140193 29304.327736709125 23288.47090266015 18486.387475488107 16096.926538536178 19186.596127901794 14239.119237969628 18775.846209552958 1.9685058996228928 2.1111655169438617 1.4509298450442814 1.560746046258058 1.240342014029238 0.984583452014132 0.8573209622022909 1.0218765063243782 0.7583743006333803 1.0 14.196590309649292 -5.810063250057225 0.7042973048942994 0.8736171375097967 2.198592417541824 0.9097909137877895 0.13280582234438326 0.2726744679655595 0.23788145103291708 0.0688498157217243 0.23656916331641079 1.5485910677930786e-06 5.810063250057225 1.3249752800320271 LDS(ph)PPPSPITEASEAAEAAEAGNLAVSSR ddPTM_PC-9_Lapatinib_30min_R1 6 LDSPPPSPITEASEAAEAAEAGNLAVSSR 29 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 LDS(0.886)PPPS(0.107)PIT(0.008)EASEAAEAAEAGNLAVSSR;LDS(0.668)PPPS(0.29)PIT(0.041)EAS(0.001)EAAEAAEAGNLAVSSR;LDS(0.891)PPPS(0.1)PIT(0.01)EASEAAEAAEAGNLAVSSR;LDS(0.878)PPPS(0.116)PIT(0.004)EAS(0.002)EAAEAAEAGNLAVSSR;LDS(0.749)PPPS(0.24)PIT(0.012)EASEAAEAAEAGNLAVSSR;LDS(0.448)PPPS(0.38)PIT(0.162)EAS(0.009)EAAEAAEAGNLAVSSR 145.42 1.175e-16 12851000.0 41092.49999999999 35927.1 39630.7 35792.799999999996 27877.899999999998 22350.51 21528.340000000004 22052.21 23283.800000000003 17130.82 True False 40506.51341455841 35843.91300730445 36372.41682492598 38425.121913280585 26238.176732060183 21394.630788883544 22642.97210622338 23076.836182150568 20661.333254716268 20091.859411617166 2.016065939180195 1.7840017826612606 1.8103061583187943 1.9124721672630796 1.3059108265952328 1.064840757173182 1.1269724539845802 1.148566477068194 1.028343511241664 1.0 14.294323464764785 -6.386051550908032 3.087547629266825 1.0896557991016522 1.8732460788721592 0.9619881567460514 0.07579022301338373 0.04702911357402263 0.8526162904727662 0.02507401761622003 0.02886798352045692 4.111009203841409e-07 6.386051550908032 0.783590279770507 LDS(ph)PQIR ddPTM_PC-9_Lapatinib_30min_R1 1 LDSPQIR 7 0 B7ZM87;O75044;A0A075B7E9 B7ZM87 SRGAP2 SLIT-ROBO Rho GTPase-activating protein 2 1 LDS(1)PQIR 78.098 0.028827999999999996 4044100.0 11308.0 18019.0 16145.0 19947.0 18656.0 16867.0 16082.0 12662.0 13809.0 13907.0 True False 11146.745846366774 17977.27811258407 14817.620421502266 21413.968921241372 17558.690759107223 16145.63772889741 16914.647270169666 13250.322744903595 12253.685004783452 16310.806420087301 0.6833963667571448 1.102169791583355 0.9084541891965484 1.3128700304400251 1.0765065997891503 0.9898736649227545 1.0370209071538434 0.8123646620307737 0.7512617518219474 1.0 13.993540491427582 -7.7587606119408985 24.947937838823115 0.8363598762771449 1.0277211302600175 0.16923755158618692 0.16066460331572982 101.8132360796968 948239.0954707185 0.07870773789253421 0.04277562915529563 1.7427672418142778e-08 7.7587606119408985 0.19136125398287263 LDS(ph)PTMSR ddPTM_PC-9_Lapatinib_30min_R1 2 LDSPTMSR 8 0 P19634 P19634 SLC9A1 Sodium/hydrogen exchanger 1 1 LDS(0.862)PT(0.137)MSR;LDS(0.954)PT(0.046)MSR 114.86 0.0036591 11010400.0 98607.0 246040.0 91958.0 48645.0 104042.0 66938.0 63570.0 64084.0 125100.0 36679.0 True False 97200.84609769077 245470.30949665242 84397.56820814534 52222.51557496296 97922.45411444227 64075.21778009932 66861.343549601 67061.57659014384 111009.92063859873 43018.91627830465 2.2594908125733335 5.706101657899 1.9618710908974903 1.2139430765088772 2.2762650151609383 1.4894661075507802 1.554231239044964 1.5588857737907362 2.5804908687247288 1.0 15.392683560758382 -5.415643839221952 8.342354881238654 1.695490329143722 3.9742079402511856 0.515816081508347 0.8865487506745062 0.2069489060817617 14.571735405149058 0.21133299840484174 0.4411833803771764 3.840220492245454e-06 5.415643839221952 2.2787176111074636 LDS(ph)SPSVSSTLAAK ddPTM_PC-9_Lapatinib_30min_R1 1 LDSSPSVSSTLAAK 14 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 LDS(0.736)S(0.264)PSVSSTLAAK 218.45 1.3917999999999999e-15 338390000.0 56942.0 127590.0 127300.0 101180.0 122540.0 106910.0 130430.0 122560.0 111630.0 106760.0 True False 56129.996638116114 127294.57319410639 116833.88539221059 108621.11472658538 115332.43812290943 102337.70851938242 137183.02720110872 128254.58502727703 99057.05388398694 125213.32375124175 0.44827495155090846 1.0166216292365131 0.9330787003491866 0.8674884706549304 0.9210875861105449 0.8173068604319955 1.0955944870024126 1.0242886394588269 0.7911063369005455 1.0 16.93402855976732 -4.755924196820393 24.99704627991675 0.9393301011856404 0.44827417333767244 0.7228329384983686 0.09147919621070416 94.28094620503887 427274.6005546747 0.022809668847172258 0.1936095817730001 1.754186656599984e-05 4.755924196820393 -0.491055927847968 LDS(ph)SPVSSPR ddPTM_PC-9_Lapatinib_30min_R1 1 LDSSPVSSPR 10 0 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 LDS(0.813)S(0.187)PVSSPR 134.75 3.2939e-05 0.0 24836.0 24663.0 23885.0 21721.0 22737.0 26776.0 20235.0 21443.0 27041.0 19756.0 True False 24481.834085635397 24605.894338790196 21921.26749876627 23318.434799131875 21399.65436266193 25630.852897904617 21282.669289384594 22439.32006152013 23995.357825646268 23170.79827678471 1.0565813828764044 1.0619355468405824 0.9460730371438962 1.0063716631849964 0.9235613769985075 1.1061704733576092 0.9185125620254582 0.9684310308809058 1.0355861519750789 1.0 14.500020128116438 -5.240205323549143 24.153196873210298 0.9870416432089878 1.0592585001099297 0.22518616172542838 0.05277775284500604 740.0647046258713 841799.496556566 0.01278281846143178 0.03373391406556434 5.751679480532222e-06 5.240205323549143 0.07221685690094193 LDSDAGFHS(ph)LPR ddPTM_PC-9_AZD4547_30min_R2 2 LDSDAGFHSLPR 12 0 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 LDSDAGFHS(1)LPR;LDS(0.001)DAGFHS(0.999)LPR 99.238 0.0019316 13774800.0 67448.0 63467.0 101355.0 138303.0 123652.0 128095.0 90180.0 107249.0 91181.0 98356.0 True False 88895.06099444749 83981.46658517027 100010.96647581954 106419.3801100496 106485.05418888478 120085.1994003609 98205.8452981915 90676.13138684354 96000.6415102991 94912.58637723644 0.9365992898047062 0.8848296078602295 1.0537165858943012 1.1212356987837067 1.1219276415632884 1.265218913359649 1.0346978103395663 0.9553646660353894 1.0114637602302619 1.0 16.53431179556275 -5.3317728362503205 4.9780173771866005 1.079648231282989 0.9108055766445594 0.37330157814460174 0.08248898489653059 0.2196860801747818 10.327799026796242 0.02419066605226771 0.05317587943426314 4.658296884862205e-06 5.3317728362503205 -0.1688426546384295 LDSDAGFHS(ph)LPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LDSDAGFHSLPR 12 0 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 LDSDAGFHS(1)LPR;LDSDAGFHS(1)LPR;LDSDAGFHS(1)LPR 85.988 0.0053083 9403900.0 39266.0 42860.6 73374.0 83094.0 79503.0 75368.0 67152.0 48580.0 56547.0 52751.0 True False 45912.95826114905 47115.51711216263 75123.51443244476 78438.51257438281 63924.95786706079 71415.56940221877 60790.87642162166 47304.82647476474 57373.89289858622 62314.338723313755 0.7367960440856217 0.7560943127610409 1.2055574362428192 1.2587554354490245 1.0258466859593658 1.146053554693343 0.9755519783583594 0.7591322871098127 0.9207173513199916 1.0 15.927276549617856 -7.53301949914755 24.087920420377355 0.8774232382294014 1.0314654146014386 0.0985190176067211 0.16990652461236272 307.89560309100744 731345.7698612825 0.0875658177641888 0.05064054620046568 2.9307616556509302e-08 7.53301949914755 0.1540421763720372 LDSDAGFHS(ph)LPR ddPTM_PC-9_Lapatinib_30min_R1 2 LDSDAGFHSLPR 12 0 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 LDS(0.013)DAGFHS(0.987)LPR;LDSDAGFHS(1)LPR 123.72 0.00019468 15324400.0 136795.0 124690.0 168972.0 121485.0 119855.0 129014.0 107213.0 110537.0 123245.0 89066.0 True False 134844.27821486918 124401.2879659307 155079.77441078195 130419.41216208 112805.36454399624 123496.3719663229 112763.96454276204 115672.95255515781 109363.85027261484 104460.939427015 1.2908583720815807 1.190888083606099 1.484571891287015 1.2484993230718715 1.0798808163391194 1.182225362357646 1.079484495939731 1.1073321108314984 1.0469353508832402 1.0 16.672604057609625 -6.151312346303668 4.138982366211598 1.0928512273508018 1.316393851163823 0.648011620677801 0.08060516606977924 0.15311187755742484 4.496785442381305 0.024170487690094482 0.03181434751179917 7.058097505222679e-07 6.151312346303668 0.22354262381302115 LDSDAVNTIESQSVS(ph)PDHNKEPK ddPTM_PC-9_AZD4547_30min_R2 2 LDSDAVNTIESQSVSPDHNKEPK 23 1 Q3T7B4;Q9H3H1-6;Q9H3H1-3;Q9H3H1-2;Q9H3H1-5;Q9H3H1-4;Q9H3H1 Q3T7B4 TRIT1 tRNA dimethylallyltransferase, mitochondrial 1 LDSDAVNTIES(0.262)QS(0.262)VS(0.477)PDHNKEPK;LDSDAVNTIESQS(0.256)VS(0.743)PDHNKEPK 90.882 7.941699999999999e-06 14777400.0 94443.0 91883.0 119639.0 136440.0 142950.0 136636.0 122945.0 148881.0 112574.0 127308.0 True False 124473.90946356555 121582.3828800036 118052.50868926605 104985.86597698656 123103.85999661243 128092.1293201743 133886.86682397622 125874.862395031 118524.4318156239 122850.98566953941 1.0132105069013584 0.9896736458187786 0.9609406717079102 0.8545789470455795 1.002058382565633 1.042662609681726 1.0898314416794552 1.0246141836714733 0.9647820989767747 1.0 16.90654990734936 -6.512749516741753 24.64897074507507 1.0291576572936465 0.9539039349332202 0.31347185944981437 0.04856997742382597 499.2580637628323 1214923.238055061 0.016585220467925647 0.017589335699548667 3.0707925850494623e-07 6.512749516741753 -0.07525372236042627 LDSDAVNTIESQSVS(ph)PDHNKEPK ddPTM_PC-9_Lapatinib_30min_R1 2 LDSDAVNTIESQSVSPDHNKEPK 23 1 Q3T7B4;Q9H3H1-6;Q9H3H1-3;Q9H3H1-2;Q9H3H1-5;Q9H3H1-4;Q9H3H1 Q3T7B4 TRIT1 tRNA dimethylallyltransferase, mitochondrial 1 LDSDAVNTIES(0.004)QS(0.318)VS(0.678)PDHNKEPK;LDSDAVNTIESQS(0.017)VS(0.983)PDHNKEPK 103.4 1.3424e-06 10608700.0 90816.0 93777.0 99468.0 91727.0 107850.0 93716.0 78122.0 85773.0 97679.0 75801.0 True False 89520.94718638534 93559.86511814188 91290.12499758361 98472.90957230187 101506.47504125832 89707.98514266613 82166.77490611818 89758.32670973109 86677.36241452991 88903.10185151648 1.006949648797415 1.0523802113721858 1.0268497172354445 1.1076431251720398 1.141765280707434 1.0090534894102339 0.9242284374211248 1.0096197414983674 0.9749644344164287 1.0 16.439946135474372 -6.989971503462606 24.980331896203886 0.9763813880455242 1.0672228023616386 0.516987537862279 0.041301440788258814 174.87712194230937 435605.2130897255 0.015343544368555399 0.013516661613437772 1.0233601385719049e-07 6.989971503462606 0.09084141431611437 LDSQPQET(ph)SPELPR ddPTM_PC-9_AZD4547_30min_R2 1 LDSQPQETSPELPR 14 0 O14545 O14545 TRAFD1 TRAF-type zinc finger domain-containing protein 1 1 LDSQPQET(0.655)S(0.345)PELPR 105.17 0.0024368000000000003 330810000.0 22991.0 21432.0 33594.0 41965.0 35078.0 31326.0 28709.0 33180.0 27667.0 26226.0 True False 30301.659757492256 28359.474874397216 33148.52161007032 32290.617602786886 30208.025190354423 29367.18026789265 31264.045383297627 28052.793400548922 29129.421136700024 25307.835722573127 1.197323235762311 1.1205808029290392 1.3098125803188991 1.2759138298809771 1.1936234106107544 1.16039872353442 1.2353504158165491 1.1084627586517584 1.1510040390659824 1.0 14.62729651576859 -8.654133976849623 0.6312341061949347 0.9988112479070166 1.220077698961982 0.5761517238570502 0.05510683395386802 0.735360104056494 0.6499799962693035 0.06066026520739998 0.024390675969232018 2.2175122270572726e-09 8.654133976849623 0.22126645105496534 LDSQPQET(ph)SPELPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LDSQPQETSPELPR 14 0 O14545 O14545 TRAFD1 TRAF-type zinc finger domain-containing protein 1 1 LDSQPQET(0.5)S(0.5)PELPR;LDSQPQET(0.912)S(0.088)PELPR;LDS(0.001)QPQET(0.862)S(0.136)PELPR;LDS(0.002)QPQET(0.7)S(0.297)PELPR;LDS(0.005)QPQET(0.498)S(0.498)PELPR 223.14 6.5341e-20 534101000.0 100520.0 102676.0 119406.7 122907.0 141347.0 124497.0 120059.0 106349.0 107205.0 99574.0 True False 117536.0506395023 112868.99471795584 122253.80858043153 116020.91925987032 113651.07001792947 117968.15815555734 108686.14236811211 103557.45143607966 108772.67031306605 117625.97797264942 0.9992354806761476 0.9595583957159559 1.0393436100387465 0.9863545558520048 0.9662072271514358 1.0029090528198412 0.9239977787337419 0.8803960929460583 0.924733398079445 1.0 16.843847192378306 -7.2685267767425445 23.54308495606341 0.9223148118767374 0.9914676714642976 0.40763520608815984 0.034592824892791564 218.00601018943453 724171.4053782551 0.01377056696447126 0.009522995096173024 5.388566207516936e-08 7.2685267767425445 0.06915285958756023 LDSQPQET(ph)SPELPR ddPTM_PC-9_Lapatinib_30min_R1 2 LDSQPQETSPELPR 14 0 O14545 O14545 TRAFD1 TRAF-type zinc finger domain-containing protein 1 1 LDS(0.002)QPQET(0.666)S(0.332)PELPR;LDSQPQET(0.715)S(0.285)PELPR 162.64 0.0013464 216860000.0 84975.0 81630.0 90635.0 70072.0 75851.0 80975.0 72699.0 65248.0 83403.0 57926.0 True False 83763.24091749369 81440.99075033232 83183.3401612174 75225.3286333396 71389.59330880373 77511.88801194457 76462.998501061 68279.66027953479 74009.2758674744 67938.43191845673 1.232928676040547 1.198746989746276 1.224392995426483 1.1072573580095135 1.0507983668873793 1.1409137041163742 1.1254748798564544 1.0050226116712204 1.0893580228095965 1.0 16.051940299421354 -1.5228787452803376 0.17649879303917698 0.9907384020222572 2.081676038930518 0.7194268159644064 0.0422978446070435 31.677614071094773 0.3521002271526957 0.10477441161020601 9.216305969393233 0.029999999999999995 1.5228787452803376 1.0909376369082606 LDSQPQETS(ph)PELPR ddPTM_PC-9_AZD4547_30min_R2 3 LDSQPQETSPELPR 14 0 O14545 O14545 TRAFD1 TRAF-type zinc finger domain-containing protein 1 1 LDSQPQET(0.231)S(0.769)PELPR;LDSQPQET(0.215)S(0.785)PELPR;LDSQPQET(0.227)S(0.773)PELPR 192.4 6.6666e-07 505250000.0 113326.0 114447.0 156614.0 212730.0 180845.0 140761.0 122247.0 169333.0 126219.0 132764.0 True False 149361.31067276653 151439.75461693434 154537.19603023017 163688.38514573715 155737.7933619264 131959.19241808174 133126.7461761814 143166.47573523666 132890.6786588043 128115.97277021671 1.1658289551503038 1.1820520996905683 1.2062289555994818 1.2776579032758202 1.2156001316186467 1.0299979742163614 1.0391112310012411 1.1174756171270999 1.037268622993257 1.0 16.967090828335216 -6.757567567331573 24.97810639586619 1.0517591884705246 1.2115579740586007 0.8161518312534701 0.039008776133199474 44.328700624616324 285976.6131740715 0.013884383238571718 0.013391899025967978 1.7475613564919884e-07 6.757567567331573 0.15979878558807603 LDSQPQETS(ph)PELPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LDSQPQETSPELPR 14 0 O14545 O14545 TRAFD1 TRAF-type zinc finger domain-containing protein 1 1 LDS(0.002)QPQET(0.081)S(0.917)PELPR;LDSQPQET(0.216)S(0.784)PELPR;LDSQPQET(0.213)S(0.787)PELPR;LDSQPQET(0.214)S(0.786)PELPR 178.47 5.995600000000001e-05 123948500.0 121118.0 126058.0 140297.0 148442.0 164840.0 151922.0 139849.0 135029.0 125894.0 111227.0 True False 141620.88521045816 138572.20515170082 143642.21255933552 140125.2759954574 132540.78531384072 143954.94287660392 126601.49030091985 131484.63182505153 127734.96158195163 131391.5746275524 1.0778536265502727 1.054650616255288 1.0932376217159223 1.066470786979012 1.0087464564569373 1.0956177615243907 0.9635434437846512 1.0007082432626513 0.9721701101766536 1.0 17.00351324147634 -7.266145123543297 24.999617003742966 0.9841644672519755 1.0642198227112964 0.7195131993102646 0.025062380080712408 221.4238289142889 1176321.5205095315 0.010114274176546397 0.007062917302030831 5.418198060166575e-08 7.266145123543297 0.08005535545932096 LDSQPQETS(ph)PELPR ddPTM_PC-9_Lapatinib_30min_R1 4 LDSQPQETSPELPR 14 0 O14545 O14545 TRAFD1 TRAF-type zinc finger domain-containing protein 1 1 LDSQPQET(0.228)S(0.772)PELPR;LDSQPQET(0.23)S(0.77)PELPR;LDSQPQET(0.052)S(0.947)PELPR;LDS(0.002)QPQET(0.379)S(0.618)PELPR 179.66 5.6705e-05 625396300.0 63534.0 62356.0 72744.0 57660.0 61795.0 65595.0 53570.0 59030.0 66741.0 43847.200000000004 True False 62627.993509291315 62211.618513141184 66763.26911996052 61900.50874812138 58160.33959364445 62789.6547594134 56343.5924799769 61772.74929960979 59223.925766112865 51426.130097278496 1.217824350983113 1.209727786155806 1.2982363050392873 1.2036781424351664 1.130949178630152 1.220967913405879 1.0956218633094976 1.2011938130043902 1.1516310026456187 1.0 15.650213972097914 -14.522878745251116 0.11092543465131519 0.36235805637916507 1.3036704895404452 0.664285586147335 0.0453349889249352 101.70065575809186 0.7455426488534861 14.604552323132497 0.5627743476856052 3.000000000201853e-15 14.522878745251116 0.9413124331612801 LDSS(ph)ACLHAVGDK ddPTM_PC-9_AZD4547_30min_R2 1 LDSSACLHAVGDK 13 0 E5RJP4;O94808 E5RJP4 GFPT2 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 1 LDS(0.449)S(0.551)ACLHAVGDK 56.872 0.040603 4381300.0 68529.0 74470.0 98215.0 121660.0 101180.0 97001.0 82197.0 100700.0 73842.0 97026.0 True False 90319.79650825064 98540.97115977795 96912.60492745906 93613.16662826293 87132.90349392948 90935.512135793 89512.37376331147 85139.12885579484 77745.13736856917 93629.14927241612 0.9646546744269048 1.0524603921485047 1.0350687331942925 0.9998292984153184 0.9306172721960159 0.9712307848831786 0.9560310486520944 0.9093228926824981 0.8303518506012261 1.0 16.51467012905777 -6.561328134439591 0.9241203907017769 0.9144360809162367 1.0227480300533969 0.3925852061660534 0.04774457514436748 0.5467848671162444 1.0195033480349882 0.026592014636780712 0.030386622415087973 2.745818745294393e-07 6.561328134439591 0.10831194913716014 LDSS(ph)PSVSSTLAAK ddPTM_PC-9_AZD4547_30min_R2 4 LDSSPSVSSTLAAK 14 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 LDS(0.001)S(0.999)PS(0.001)VSSTLAAK;LDS(0.052)S(0.658)PS(0.267)VS(0.017)S(0.004)T(0.002)LAAK;LDS(0.009)S(0.99)PS(0.001)VSSTLAAK;LDS(0.011)S(0.985)PS(0.004)VSSTLAAK 206.67 8.042e-11 693353000.0 251112.0 325490.0 313630.0 312960.0 290094.0 325543.0 300512.0 368490.0 295728.0 281129.0 True False 330960.3925459269 430698.2771961345 309471.0612777984 240811.90718380015 249819.45548693484 305186.74474719394 327256.98583111644 311548.3375578148 311359.5783393225 271286.7592790076 1.2199651520977746 1.5876125998216466 1.1407525457573833 0.8876655382068784 0.9208685899410427 1.1249599706166329 1.2063138897779588 1.1484096694796657 1.1477138772523048 1.0 18.049459110008414 -5.434101428066748 6.684578276173971 1.0669834106338874 1.3998300328016442 0.5281396434470317 0.12717733446104384 0.19220867882793416 12.177864462439736 0.03510264169807093 0.07357465696717057 3.680430083543454e-06 5.434101428066748 0.33284662216775684 LDSS(ph)PSVSSTLAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LDSSPSVSSTLAAK 14 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 LDS(0.046)S(0.941)PS(0.013)VSSTLAAK;LDS(0.004)S(0.987)PS(0.008)VSSTLAAK;LDS(0.274)S(0.726)PSVSSTLAAK;LDS(0.226)S(0.763)PS(0.011)VSSTLAAK;LDS(0.1)S(0.886)PS(0.014)VSSTLAAK;LDS(0.057)S(0.942)PS(0.001)VSSTLAAK 211.75 1.4972999999999998e-11 634333000.0 626221.0 937912.0 796675.0 727069.0 837297.0 544760.0 798415.0 579929.0 509232.0 500922.0 True False 732227.8468714682 1031021.7049155327 815670.7534067644 686333.6811195017 673234.6634368048 516191.8266048282 722783.3511759742 564706.4782355664 516678.5546277041 591735.19330363 1.2374248737572533 1.7423700949057748 1.3784388061371042 1.1598662524831973 1.1377296315234642 0.8723358563869648 1.2214641943817952 0.9543229549738904 0.8731584000321356 1.0 19.174592176005604 -5.878296024735218 1.800627767252066 1.0069949440319557 1.504838589078319 0.6331095459862882 0.15203542405976914 0.2111770998802982 1.3953003220716753 0.047340179265812875 0.086806954435244 1.3234391422605232e-06 5.878296024735218 0.49784364504636325 LDSS(ph)PSVSSTLAAK ddPTM_PC-9_Lapatinib_30min_R1 3 LDSSPSVSSTLAAK 14 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 LDS(0.099)S(0.896)PS(0.004)VSSTLAAK;LDS(0.078)S(0.922)PSVSSTLAAK;LDS(0.062)S(0.938)PSVSSTLAAK 232.78 1.0331e-26 337505000.0 124046.0 245266.0 222307.0 202293.0 252954.0 216043.0 256691.0 240522.0 224872.0 187608.0 True False 122277.08129274989 244698.10164609752 204029.7765898362 217170.30204966498 238075.74304669842 206803.34451083062 269981.2039812911 251697.53018873069 199544.54735286167 220035.79282805338 0.5557145031776858 1.1120831683839567 0.9272572155988955 0.9869771606630034 1.0819864349648893 0.939862291733767 1.2269876664669164 1.14389357728458 0.9068731263590167 1.0 17.74737869789294 -4.756241517004044 24.99936413116518 1.0401477081105852 0.5557137502473162 0.6802638381276648 0.09879276736499192 96.29605088329842 463089.45137480664 0.024784840844921475 0.20452168450590005 1.7529054164535336e-05 4.756241517004044 -0.48443395786326904 LDSSEMDHS(ph)ENEDYTMSSPLPGK ddPTM_PC-9_AZD4547_30min_R2 4 LDSSEMDHSENEDYTMSSPLPGK 23 0 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 LDS(0.002)S(0.005)EMDHS(0.992)ENEDY(0.001)TMSSPLPGK;LDSS(0.002)EMDHS(0.954)ENEDY(0.015)T(0.026)MS(0.002)S(0.001)PLPGK;LDS(0.058)S(0.054)EMDHS(0.712)ENEDY(0.087)T(0.059)MS(0.02)S(0.009)PLPGK;LDS(0.008)S(0.008)EMDHS(0.626)ENEDY(0.14)T(0.206)MS(0.009)S(0.002)PLPGK 76.78 0.00017405 22916800.0 105247.4 117409.0 172086.0 197248.0 166087.0 164551.0 157847.0 207753.0 147753.0 169440.0 True False 138713.88391808473 155359.16319186753 169804.02720100502 151775.52105122147 143028.6869203032 154261.59995728827 171895.07720984294 175649.54753900645 155562.92193627212 163507.9571735221 0.848361671908574 0.950162706925592 1.038506199553342 0.9282454730331586 0.8747506200478956 0.9434501086303637 1.0512948738477605 1.074256877618495 0.951408877129947 1.0 17.319001321141464 -7.200400177310345 6.682673073758379 1.0252974472599183 0.933298370958445 0.3743421676337816 0.05591474584061591 0.27352853731289 24.83167635828453 0.022562964480299492 0.01735878241774671 6.303762214643747e-08 7.200400177310345 -0.0919990763014733 LDSSEMDHS(ph)ENEDYTMSSPLPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LDSSEMDHSENEDYTMSSPLPGK 23 0 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 LDS(0.012)S(0.012)EMDHS(0.723)ENEDY(0.236)T(0.015)MS(0.001)SPLPGK 85.84899999999999 1.6462999999999998e-05 5118400.0 42361.0 61662.0 54482.0 59432.0 61433.0 42542.0 49134.0 37576.0 41606.0 35421.0 True False 49531.880632112625 67783.39585003883 55781.057504135584 56102.217721143745 49395.64465048045 40311.02262908917 44479.671820645075 36589.66981506295 42214.40903918117 41842.54690751828 1.1837683002803236 1.619963430998974 1.333118120831044 1.3407935670154745 1.1805123803686297 0.9633979193041444 1.0630249616247178 0.8744608662549772 1.008887177266833 1.0 15.3526830489884 -6.453133791372215 1.6559829843998208 0.9711263603449045 1.401798243419899 0.7317724361075694 0.11024601901554845 0.17581705556543778 0.9695789059230233 0.04006068447216692 0.04632974481407895 3.522623342700553e-07 6.453133791372215 0.4306718830749945 LDSSEMDHS(ph)ENEDYTMSSPLPGKK ddPTM_PC-9_AZD4547_30min_R2 3 LDSSEMDHSENEDYTMSSPLPGKK 24 1 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 LDS(0.158)S(0.158)EMDHS(0.678)ENEDY(0.005)T(0.001)MSSPLPGKK;LDS(0.165)S(0.165)EMDHS(0.55)ENEDY(0.096)T(0.023)MSSPLPGKK;LDS(0.007)S(0.007)EMDHS(0.774)ENEDY(0.16)T(0.047)MS(0.005)S(0.001)PLPGKK 58.835 0.0017885000000000002 24283600.0 76541.0 69101.0 112734.0 144916.0 125918.0 104069.0 87756.0 118534.0 82200.0 107726.0 True False 100879.44584829765 91436.54690629528 111239.07350091297 111507.85512988127 108436.4592028923 97561.54897846276 95566.11399410176 100217.2939403457 86544.92418537398 103954.54552924247 0.9704188050143532 0.8795819984665714 1.0700741649591585 1.0726597337536725 1.043114167358743 0.9385020008674718 0.9193067364930084 0.9640491758213162 0.8325265984740305 1.0 16.665593317473117 -6.870493163287672 6.497620210903101 0.9265458451960389 1.006987402542167 0.2534726167775716 0.06549569518970766 0.3287662146759963 17.689032471482903 0.024587733264202494 0.02170352060621748 1.3474319366017617e-07 6.870493163287672 0.08044155734612812 LDSSEMDHS(ph)ENEDYTMSSPLPGKK ddPTM_PC-9_Lapatinib_30min_R1 2 LDSSEMDHSENEDYTMSSPLPGKK 24 1 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 LDS(0.043)S(0.043)EMDHS(0.909)ENEDY(0.003)T(0.001)MSSPLPGKK;LDS(0.012)S(0.012)EMDHS(0.911)ENEDY(0.034)T(0.021)MS(0.006)S(0.004)PLPGKK 61.303999999999995 0.0011795999999999998 28528000.0 39842.0 35730.0 44644.0 34249.0 29017.0 30135.0 29462.0 27265.0 32191.0 21840.7 True False 39273.84577387202 35647.26938024467 40973.542650823605 36767.78571131476 27310.277109616974 28846.19629811605 30987.39820132687 28531.831435776076 28565.310593742073 25615.835894096574 1.5331861874912724 1.391610624288077 1.5995395512455781 1.4353537344369178 1.066148191397139 1.1261079442175825 1.209696936279492 1.113835658291031 1.1151426294203124 1.0 14.644748350029865 -6.189682694725167 4.811750344045807 1.1171148428995032 1.497911848745572 0.8783785679700169 0.07026649106385528 0.07166979929652922 3.1595184082907544 0.020503169422627525 0.026577103790951177 6.461261308443284e-07 6.189682694725167 0.3807970058460688 LDSSEMDHSENEDY(ph)TMSSPLPGK ddPTM_PC-9_AZD4547_30min_R2 1 LDSSEMDHSENEDYTMSSPLPGK 23 0 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 LDS(0.003)S(0.003)EMDHS(0.175)ENEDY(0.593)T(0.206)MS(0.014)S(0.005)PLPGK 68.291 0.00044256 12761000.0 76870.0 76805.0 107720.0 126810.0 116570.0 105810.0 97070.0 123980.0 101630.0 110760.0 True False 101313.06100467294 101630.71424636416 106291.56241700235 97575.91369496961 100386.26764466686 99193.68397324026 105709.04195049284 104821.739776976 107001.95431824282 106882.32611272026 0.9478934889368532 0.9508654792859051 0.9944727653560339 0.9129284255290635 0.9392223325940482 0.9280644198239903 0.9890226550553358 0.980720981562741 1.001119251515881 1.0 16.70566378551606 -7.280951786349127 21.709440836275892 0.9911091848493538 0.9462649945496346 0.5628881447425396 0.02032611403110495 127.59633897619413 141961.04619585787 0.00884790646198434 0.005982270171129896 5.2365856785619665e-08 7.280951786349127 -0.0448441902997192 LDSSEMDHSENEDYT(ph)MSSPLPGK ddPTM_PC-9_Lapatinib_30min_R1 1 LDSSEMDHSENEDYTMSSPLPGK 23 0 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 LDSSEMDHS(0.001)ENEDY(0.446)T(0.526)MS(0.021)S(0.006)PLPGK 72.568 0.0008257 9466500.0 54153.0 72153.0 80269.0 62544.0 65588.0 66572.0 59957.0 54379.0 66873.0 41876.0 True False 53380.76828955604 71985.93416156698 73669.59266730052 67143.69440066774 61730.24279096927 63724.87074691167 63061.28008814587 56905.646860299516 59341.058536091216 49114.21080373742 1.0868701220277768 1.465684431930017 1.499964907543511 1.367093012427237 1.2568713164840637 1.2974833496064733 1.2839721753881288 1.1586391378189302 1.208225838611573 1.0 15.583852896752736 -8.252383443064646 0.5353105236891434 1.0021960966060979 1.3653973623630706 0.462236963345777 0.10970835622973664 0.7503171779931247 0.5338477169361356 0.11848364106061428 0.061361339280076393 5.592636038617159e-09 8.252383443064646 0.36320126575697276 LDSSPS(ph)VSSTLAAKDDPDGK ddPTM_PC-9_Lapatinib_30min_R1 1 LDSSPSVSSTLAAKDDPDGK 20 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 LDS(0.1)S(0.1)PS(0.411)VS(0.228)S(0.081)T(0.081)LAAKDDPDGK 64.249 0.0032889000000000004 5362600.0 18640.0 22154.0 23504.0 28922.0 34982.0 26212.0 27094.0 26178.0 32297.0 22919.0 True False 18374.190181842656 22102.703774137706 21571.591848063752 31049.02036096367 32924.42753725816 25090.9738631564 28496.79474803985 27394.32544748745 28659.371757512596 26880.51861235214 0.6835504346779732 0.8222573415671031 0.8024990945729435 1.1550751980914542 1.2248434642227743 0.9334259589629565 1.060128160434561 1.019114468829452 1.066176295584678 1.0 14.714273352199267 -5.695642888206111 6.640412933893755 1.06694876881112 0.7702233015825303 0.7300424855858428 0.08259579182532359 0.11410845399063602 9.024962565339244 0.023555666104982123 0.04085834737768476 2.01538077660018e-06 5.695642888206111 -0.29672546722858983 LDT(ph)PDINIVLK ddPTM_PC-9_AZD4547_30min_R2 1 LDTPDINIVLK 11 0 P30414;A0A087WYW3 P30414 NKTR NK-tumor recognition protein;Putative peptidyl-prolyl cis-trans isomerase 1 LDT(1)PDINIVLK 88.155 0.024406 8231000.0 12349.0 15141.0 12333.0 12779.0 13691.0 15930.0 14405.0 13957.0 11411.0 13964.0 True False 16275.725124843277 20035.03215160732 12169.456361760958 9832.998983581881 11790.240973862325 14933.894581738172 15687.017093817352 11800.266349953628 12014.162163981782 13475.124610310802 1.207834850921492 1.4868160949158906 0.903105293174745 0.7297148833828175 0.874963409602962 1.1082565106901614 1.1641463472489204 0.8757074009485881 0.8915807839571939 1.0 13.718010993814518 -5.270234146810207 24.89975758973175 0.9426861464604855 1.3473254765094573 0.5955290463654909 0.1331412899663168 383.50096426579546 1085770.4221465322 0.037840084308062814 0.08068417433901826 5.367423374976279e-06 5.270234146810207 0.4046393300489718 LDTDDLDEIEK ddPTM_PC-9_Lapatinib_30min_R1 2 LDTDDLDEIEK 11 0 I3L0H8;F6QDS0;H3BQK0;Q9UMR2-2;Q9UMR2-4;Q9NUU7;Q9UMR2;I3L352;Q9UMR2-3;Q9NUU7-2 I3L0H8 DDX19A;DDX19B ATP-dependent RNA helicase DDX19B;ATP-dependent RNA helicase DDX19A 0 ; 165.11 0.0016349000000000001 5418100.0 30763.0 38252.0 43820.0 36151.0 36435.0 30771.0 35159.0 32690.0 33143.0 34045.0 False True 30324.31397875673 38163.42984419588 40217.288750091626 38809.66513620077 34291.9649339661 29454.996060704456 36979.36098569177 34208.896740712255 29410.08632873764 39929.632887889 0.7594438462256525 0.9557671103901177 1.0072040697947382 0.9719514638455911 0.8588099227019727 0.737672598779099 0.926113222466113 0.8567295581394666 0.7365478768941544 1.0 15.285172187476917 -6.392124124342762 6.324252790914829 0.8421190323742658 0.9313980274589156 0.11038132042243809 0.09584118246031466 0.45469747032792307 21.45565729951685 0.029754562617831975 0.033725924147230996 4.0539265488714705e-07 6.392124124342762 0.08927899508464987 LDTGPQS(ph)LSGK ddPTM_PC-9_AZD4547_30min_R2 1 LDTGPQSLSGK 11 0 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 LDT(0.27)GPQS(0.61)LS(0.12)GK 88.021 0.010055 4913700.0 24858.0 28026.0 34403.0 41966.0 29187.0 32910.0 34324.0 28758.0 25132.0 30802.0 True False 32762.32692147985 37084.85642169917 33946.793741479116 32291.38706823673 25134.88885429256 30852.132497489205 37378.7695056013 24314.111893097845 26460.42621200512 29723.631355399146 1.1022316395243794 1.2476556440322994 1.142080970376214 1.0863876853448853 0.8456197210145703 1.0379664627311789 1.2575438397371874 0.8180061043813649 0.8902151253197641 1.0 14.859322761186078 -5.952839001444884 3.6882036410503334 0.981618120478787 1.1709645134688285 0.3314288015330158 0.12070396737600547 0.28568056051499047 8.131464059218686 0.037361543739427315 0.056193099455949774 1.1147076934967655e-06 5.952839001444884 0.1893463929900414 LDTGPQS(ph)LSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LDTGPQSLSGK 11 0 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 LDT(0.129)GPQS(0.559)LS(0.312)GK;LDT(0.003)GPQS(0.73)LS(0.267)GK 100.22 0.0042369 30323000.0 68282.0 108400.0 87536.0 89420.0 74574.0 41166.0 38081.0 43433.0 30874.0 23163.0 True False 79840.79396902614 119161.23560935738 89623.19022212844 84410.0873035513 59961.760033938204 39007.18249139875 34473.691997435286 42292.929771067444 31325.47384213045 27362.268541792873 2.917915736667742 4.354947230612535 3.2754298162536784 3.0849082258886584 2.191403097384019 1.4255829129013753 1.259898898542732 1.5456660585897555 1.144841985388902 1.0 14.73990022520894 -6.358500941673308 1.3754343814532197 1.2522412938110896 3.6390232452910425 0.8891054667887659 0.35804024057084904 0.12154042701984823 0.46641602257212905 0.13613643526269023 0.17512539212036943 4.3802516140685447e-07 6.358500941673308 2.3867819514799526 up LDTGPQSLS(ph)GK ddPTM_PC-9_AZD4547_30min_R2 3 LDTGPQSLSGK 11 0 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 LDTGPQS(0.228)LS(0.772)GK;LDT(0.008)GPQS(0.29)LS(0.702)GK;LDT(0.014)GPQS(0.291)LS(0.695)GK 142.39 0.00014055 34638900.0 152433.0 188729.0 168354.0 230096.0 207385.0 183766.0 155409.0 185342.0 160608.0 174071.0 True False 200903.52319663425 249731.95845325265 166121.51595945042 177050.92214776235 178593.17247567308 172275.08296972318 169240.09993287508 156701.65263545964 169097.41099226935 167976.8272730891 1.1960192751468894 1.4867048182023928 0.9889549568011403 1.054019920616318 1.0632012484991422 1.0255883848171878 1.0075205174445414 0.9328766067280293 1.0066710613444225 1.0 17.357902698607276 -5.2750341491420984 24.99666442077601 1.011418014219055 1.341362044655522 0.7657371636540424 0.0733401163292874 288.0095114197674 529562.2366019381 0.018236949634228675 0.03829465530990146 5.308427017352056e-06 5.2750341491420984 0.3299440304364669 LDTGPQSLS(ph)GK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LDTGPQSLSGK 11 0 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 LDTGPQS(0.101)LS(0.899)GK;LDTGPQS(0.016)LS(0.984)GK;LDTGPQS(0.011)LS(0.989)GK;LDT(0.005)GPQS(0.033)LS(0.962)GK 114.56 0.0014457 18608300.0 66298.0 97268.0 69906.0 71055.0 66639.0 33917.7 42306.5 34202.8 31068.4 27783.2 True False 77520.9419548123 106924.12421818271 71572.8241599813 67074.0187134182 53581.5663220641 32138.996103301626 38298.922047464504 33305.01274086216 31522.716574361784 32820.0742283098 2.3619977644031227 3.257887946089791 2.180763628445554 2.0436888182160717 1.6325851656924633 0.9792481235639409 1.1669358753134318 1.014775667756841 0.960470605735896 1.0 15.002290881310683 -6.105207141106454 1.0252776780074029 0.9935705537494333 2.8272217288682477 0.8832673810672471 0.2536822922370899 0.16039498744434522 0.34827885363292177 0.10384765826097278 0.1923423177329009 7.848611979058154e-07 6.105207141106454 1.8336511751188145 up LDTGPQSLS(ph)GK ddPTM_PC-9_Lapatinib_30min_R1 4 LDTGPQSLSGK 11 0 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 LDT(0.197)GPQS(0.055)LS(0.749)GK;LDT(0.003)GPQS(0.069)LS(0.928)GK;LDTGPQS(0.337)LS(0.663)GK;LDT(0.008)GPQS(0.02)LS(0.972)GK 128.35 0.00031411 55541400.0 183224.0 219868.0 193895.0 173780.0 147783.0 134087.0 105822.0 103193.0 99953.0 76256.0 True False 180611.19216083313 219358.9091546497 177953.70155634405 186560.36091308622 139090.69449255677 128352.41158206362 111300.94536897744 107987.72350456781 88695.2405882483 89436.74799526685 2.0194293308874713 2.4526708995083157 1.9897156990296838 2.08594750027091 1.555185062184033 1.4351193939750164 1.2444654782715006 1.2074200585902644 0.9917091416711865 1.0 16.448580110928262 -6.558756976844804 0.7922830700364148 1.0430342440325235 2.2736076666096667 0.9240164741883725 0.13307679644581558 0.15157605343235178 0.211289589513729 0.07834250946894172 0.09430022566928434 2.762123056795058e-07 6.558756976844804 1.2305734225771432 up LDTGS(ph)PEPETR ddPTM_PC-9_AZD4547_30min_R2 2 LDTGSPEPETR 11 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 LDT(0.002)GS(0.998)PEPETR;LDT(0.047)GS(0.953)PEPETR 153.49 0.00019969 144896000.0 419100.0 404040.0 544420.0 661300.0 528060.0 545030.0 389160.0 576770.0 444600.0 519120.0 True False 552365.0821784626 534638.028567164 537200.6350822907 508847.5019831514 454747.9839790922 510949.1879400357 423794.4860971852 487643.4493560763 468100.6483311108 500945.76680782955 1.102644475265839 1.0672573040671272 1.0723728408875228 1.0157736339917074 0.90777887370299 1.0199690700970503 0.8459887560238816 0.9734455936487507 0.9344337837486535 1.0 18.93429489783226 -5.968870912324876 2.748932931232438 0.944088455105643 1.0808271819468043 0.6227035669538152 0.04670241033035806 0.16701835851888155 2.5638209037389714 0.013480689216622998 0.020657717440096503 1.0743086874145933e-06 5.968870912324876 0.13673872684116128 LDTGS(ph)PEPETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LDTGSPEPETR 11 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 LDT(0.002)GS(0.998)PEPETR;LDT(0.002)GS(0.998)PEPETR 128.57 0.00030349 105425000.0 348280.0 424380.0 484960.0 443440.0 465810.0 411140.0 422600.0 407960.0 363890.0 322840.0 True False 407236.9251564453 466509.6417702874 496523.28562104196 418595.4944518768 374537.87434506376 389579.094629395 382568.2686409532 397251.4822693496 369211.20283775585 381368.3363999667 1.0678309819862666 1.2232521613462617 1.3019520453850801 1.0976147060433132 0.9820895931755085 1.02152973240237 1.003146386646342 1.041647783398371 0.968122331085555 1.0 18.540825541435538 -5.997390709110934 5.541828307996917 1.0080134732022739 1.2013404805290915 0.7034770090678696 0.05676805554796435 0.08952513013252654 9.525159310345016 0.016636631139806648 0.023698202331882676 1.0060261992238099e-06 5.997390709110934 0.19332700732681762 LDTGS(ph)PEPETR ddPTM_PC-9_Lapatinib_30min_R1 1 LDTGSPEPETR 11 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 LDT(0.226)GS(0.774)PEPETR 148.89 0.00029502 70274000.0 201300.0 231480.0 226380.0 225290.0 232280.0 198590.0 190590.0 198070.0 212990.0 192820.0 True False 198429.42508610064 230944.02228208867 207767.9102520711 241858.57814540865 218617.74708005047 190096.76863590075 200457.81763596812 207273.05529008457 189000.8233158685 226148.68008349976 0.8774290657492917 1.0212043784505767 0.9187226305073193 1.06946712249706 0.9666991954113167 0.8405831445300157 0.8863983533397324 0.9165344463366055 0.8357370171078808 1.0 17.78691205014283 -6.652297071336812 7.679558773377559 0.890270178427756 0.9770474860862878 0.24628975942797282 0.06482983964836163 0.29120046064310706 18.756221555559183 0.020326611467027304 0.020296683192487154 2.226911349470991e-07 6.652297071336812 0.08677730765853175 LDTQEEPPLGS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 LDTQEEPPLGSR 12 0 Q8IW93-2;Q8IW93 Q8IW93-2 ARHGEF19 Rho guanine nucleotide exchange factor 19 1 LDTQEEPPLGS(1)R;LDT(0.003)QEEPPLGS(0.997)R 78.903 0.015968 12593500.0 13059.7 20586.5 92222.0 183852.0 103799.0 51006.0 22813.3 115277.0 34822.0 52852.0 True False 17212.412941364968 27240.683534050877 90999.07602321565 141467.76188508465 89388.30055116021 47816.58675681962 24843.639504781888 97463.58845193099 36662.61982947803 51001.66756689681 0.33748725801540014 0.5341135855669892 1.7842372683962906 2.7737869884259596 1.7526544682860266 0.9375494770656381 0.48711425900330607 1.9109882696304386 0.718851394052737 1.0 15.638256798224988 -6.776187098247074 24.514395091439997 1.0351007082145431 1.4799431711482358 0.07781033967018192 0.7224283925586793 594.5316915078785 988252.9318722711 0.28282676363024123 0.25052303116773794 1.674221449907797e-07 6.776187098247074 0.4448424629336927 LDVGNFSWGSECCTR ddPTM_PC-9_AZD4547_30min_R2 2 LDVGNFSWGSECCTR 15 0 P62241 P62241 RPS8 40S ribosomal protein S8 0 ; 177.21 0.00021790000000000004 9523800.0 19974.5 22305.1 21674.0 28929.0 25369.0 26193.0 22779.0 32343.0 25215.0 25562.0 False True 26325.975504590027 29514.787374996136 21386.588598459984 22259.86599859457 21846.952250815357 24555.147569332563 24806.286871229804 27345.13251820234 26547.813422557243 24667.08216046725 1.067251300065859 1.1965252794389307 0.8670092578981735 0.9024117994089058 0.8856723348426033 0.995462187606685 1.0056433391617616 1.1085677803444087 1.0762445776867826 1.0 14.590299450615712 -9.447340791999743 10.18241782333123 1.0000000335764883 1.008107485584452 9.502552346984938e-05 0.09998540874762335 0.0 0.0 0.10630678577616746 0.025783182733826335 3.569925952026945e-10 9.447340791999743 0.008107452007963811 LDVGNFSWGSECCTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LDVGNFSWGSECCTR 15 0 P62241 P62241 RPS8 40S ribosomal protein S8 0 99.941 0.0090505 3092700.0 6684.4 5817.4 8278.8 7459.9 9202.6 8285.2 4932.9 9433.1 6826.8 4747.8 False True 7815.936897082072 6394.913026142774 8476.197989523836 7041.945988322121 7399.416591416854 7850.70952673898 4465.6200008967335 9185.491120195618 6926.6290349632745 5608.538556435879 1.393578169862659 1.1402102279932653 1.5113024372092934 1.255575925432729 1.3193127794273458 1.3997781146980217 0.7962181156394779 1.6377690957754287 1.2350149625012148 1.0 12.453409174558756 LDVGNFSWGSECCTR ddPTM_PC-9_Lapatinib_30min_R1 2 LDVGNFSWGSECCTR 15 0 P62241 P62241 RPS8 40S ribosomal protein S8 0 ; 233.52 3.9354999999999995e-31 20444100.0 23595.0 25232.8 25218.0 23365.4 25570.1 31492.0 20945.7 20234.1 19003.1 20405.0 False True 23258.530973206933 25174.375001898603 23144.673384295093 25083.769460689484 24066.11699075081 30145.16057143755 22030.1658579028 21174.250154213692 16862.770766485664 23931.977062046557 0.97185998937348 1.0519137193149977 0.9671024388954459 1.0481277579222463 1.0056050500281057 1.2596184800479526 0.9205326330034046 0.8847681116907674 0.704612524187487 1.0 14.546651964883456 -7.509651321815305 23.18349060711042 0.8573441180950427 1.0485659405976688 0.41843905567581896 0.1016612183024971 225.27143350179696 394834.5595503004 0.043636573626163716 0.027885218340655608 3.092777507030338e-08 7.509651321815305 0.1912218225026261 LDVS(ph)NVATDTER ddPTM_PC-9_AZD4547_30min_R2 1 LDVSNVATDTER 12 0 E9PEM5;A0A494C1L5;P50851-2;P50851;A0A494C0R9;A0A494BZW2 E9PEM5 LRBA Lipopolysaccharide-responsive and beige-like anchor protein 1 LDVS(0.999)NVATDTER 77.74600000000001 0.017228999999999998 1036500.0 3914.1 4510.7 7088.5 7873.0 6181.4 6428.9 5581.7 6157.5 6260.9 4270.7 True False 5158.702381662409 5968.695563453876 6994.501858456379 6058.001486637462 5323.2193087307405 6026.899866700343 6078.460486814322 5205.999860273658 6591.838392119321 4121.184092899911 1.2517524734092715 1.4482962733300142 1.697206846572736 1.4699662403032063 1.291672293383285 1.4624194723753428 1.474930590285074 1.263229145536764 1.599501076274637 1.0 12.008843194769637 -11.358045347479118 2.7269545955272942 0.8434452471347179 1.4407248267884527 0.48763094594418843 0.13526933545425704 25599748.549351044 19710221.219595127 26331333.994581174 0.03491711722796458 4.38484910355853e-12 11.358045347479118 0.5972795796537348 LDVTILS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 3 LDVTILSPSR 10 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 1 LDVTILS(0.88)PS(0.12)R;LDVTILS(0.759)PS(0.241)R;LDVTILS(0.992)PS(0.008)R 166.24 0.00023622 57471000.0 37354.8 33420.5 43745.0 56593.0 43916.0 37578.0 33129.4 51686.0 29381.8 39585.0 True False 49232.84937189216 44223.02305150207 43164.91271752475 43546.35820313397 37819.021445339116 35228.24171955788 36077.85241984815 43699.11632612334 30934.86196386645 38199.141198736266 1.2888470218676256 1.1576967875122042 1.1299969413697908 1.139982649782048 0.9900489973997184 0.9222260138330892 0.9444676316713032 1.1439816434294345 0.8098313468076047 1.0 15.221252583196552 -5.669830534336023 0.8184981948651006 0.9643720023056968 1.2746886530767307 0.6098240415844203 0.0845322506929824 0.6603551065572697 0.7464025616341907 0.03740088458008361 0.149009607693454 2.13879650457751e-06 5.669830534336023 0.310316650771034 LDVTILS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LDVTILSPSR 10 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 1 LDVTILS(0.993)PS(0.007)R;LDVT(0.003)ILS(0.951)PS(0.046)R;LDVTILS(0.931)PS(0.069)R 109.72 0.0018429000000000002 44388000.0 38798.1 42444.0 46424.0 42169.0 48436.0 37669.0 33621.5 29389.899999999998 31508.5 29161.7 True False 45365.85203259531 46657.5598173761 47530.92422400041 39806.40764374259 38945.31350073526 35693.571327515405 30436.628121419362 28618.446266173076 31969.25220427439 34448.48536610982 1.3169186264783044 1.3544154212155142 1.37976818774044 1.155534335419689 1.1305377605672438 1.0361434167039023 0.8835403878558535 0.8307606549902977 0.9280307062709213 1.0 15.072152931337072 -6.437765255460806 1.0148320815804914 0.8945023865908202 1.358352106427167 0.901447898336765 0.059318579749100944 0.1467038034434186 0.3232517513686384 0.029482230044494302 0.03763305105001694 3.649511567581972e-07 6.437765255460806 0.46384971983634693 LDVTILS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 2 LDVTILSPSR 10 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 1 LDVTILS(0.989)PS(0.011)R;LDVTILS(0.998)PS(0.002)R 136.81 0.00011605 27540000.0 30009.0 35586.0 41707.0 28542.0 33592.0 32569.0 23682.5 29780.0 30248.0 20840.5 True False 29581.066157023375 35503.602803397305 38278.011453675725 30641.073893320856 31616.184604413033 31176.099792047175 24908.66397063753 31163.687517234957 26841.151714439144 24442.752656779307 1.2102182832021964 1.4525206429051771 1.5660270343184588 1.2535852374557501 1.2934788912018935 1.2754741755078205 1.0190613275190592 1.2749663654838634 1.0981231161374385 1.0 14.577119145093269 -6.755483704950586 1.045625571215127 1.1103450148972935 1.4005552842258198 0.5124600177078562 0.1177162739851667 0.4386255570070198 1.0254139045297213 0.06575911158859492 0.059989681037843315 1.7559667781323215e-07 6.755483704950586 0.2902102693285262 LDVTILS(ph)PSRK ddPTM_PC-9_AZD4547_30min_R2 1 LDVTILSPSRK 11 1 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 1 LDVT(0.007)ILS(0.567)PS(0.425)RK 76.357 0.030414 20279000.0 79230.0 62555.0 111470.0 160280.0 102810.0 139530.0 90378.0 103220.0 87545.0 106830.0 True False 104423.49191362302 82774.68042030228 109991.83496679584 123329.92230131492 88536.60612977778 130805.16704268185 98421.46691461465 87269.72075963429 92172.44997334019 103089.91421652131 1.0129360636997018 0.8029367474925758 1.066950494650508 1.1963335427972441 0.8588289824727471 1.2688454349467182 0.954714800789324 0.8465398523500599 0.8940976493563569 1.0 16.653543668233347 -7.516076664153229 24.84820331314629 0.9023166835289309 1.0320459871763887 0.1439011472234678 0.13411327502464576 555.8997487572626 2030743.163052912 0.06103109660702433 0.03696800523745138 3.047357005205937e-08 7.516076664153229 0.12972930364745783 LDVTILS(ph)PSRK ddPTM_PC-9_Lapatinib_30min_R1 1 LDVTILSPSRK 11 1 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 1 LDVT(0.001)ILS(0.832)PS(0.168)RK 89.663 0.013456000000000001 22958000.0 55462.0 63070.0 72353.0 61174.0 53487.0 72436.0 53708.0 43362.0 58867.0 37527.0 True False 54671.101709514885 62923.965290009255 66404.41563065675 65672.94003048167 50340.99981948795 69338.0811365633 56488.73744473772 45376.75682076365 52236.77856300876 44013.49194841564 1.24214415374245 1.429651738693147 1.5087286350395361 1.4921092856583877 1.1437629143011017 1.5753824126890088 1.283441393628645 1.0309737948978412 1.1868355872383611 1.0 15.425658216558244 -7.5959710626769725 4.61971671809837 1.0851895192335332 1.4002615499896964 0.5628059548596389 0.1280740455289953 0.15694160894667653 6.35901050454057 0.06169155652804566 0.03464504999094739 2.535297553390587e-08 7.5959710626769725 0.3150720307561632 LDVTILSPS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LDVTILSPSR 10 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 1 LDVTILS(0.241)PS(0.759)R;LDVTILS(0.132)PS(0.868)R 95.094 0.006049499999999999 21295700.0 25752.6 24326.0 22753.0 21929.7 23361.0 17394.4 18945.4 19439.5 16885.7 14705.699999999999 True False 30112.00654296507 26740.92451506671 23295.517811233014 20701.050006046655 18783.57974834167 16482.207042908864 17150.754559182013 18929.233722852805 17132.621417894083 17371.726999742856 1.7333916508940534 1.5393359863105458 1.3410018365806604 1.1916518148341315 1.081273021883185 0.9487949610970079 0.9872797655314227 1.0896575638756587 0.9862359348697851 1.0 14.08445356538321 -5.291220160874936 0.8550012195600647 1.0006709691640747 1.872482635205936 0.9754288739285312 0.039621308401996486 0.18824490814399147 0.17582087030636237 0.0170708848977332 0.1340962028148903 5.114225097229583e-06 5.291220160874936 0.8718116660418613 LDYGQHVVAGT(ph)PGR ddPTM_PC-9_AZD4547_30min_R2 1 LDYGQHVVAGTPGR 14 0 I3L3H2;P38919 I3L3H2 EIF4A3 Eukaryotic initiation factor 4A-III;Eukaryotic initiation factor 4A-III, N-terminally processed 1 LDYGQHVVAGT(1)PGR 135.57 0.00010211 5710900.0 12816.0 12524.0 15106.0 18441.0 13289.0 14722.0 17535.0 16712.0 14589.0 13662.0 True False 16891.22141063986 16572.138079831602 14905.684569914947 14189.712360609868 11444.05173483722 13801.431012702398 19095.581030203903 14129.544403555561 15360.144755966208 13183.697538389159 1.2812203375763809 1.2570174665776244 1.1306148769350626 1.0763074865219966 0.8680456830501213 1.0468558591028414 1.4484237805517104 1.071743671486108 1.1650862522626544 1.0 13.686467429119544 LDYGQHVVAGT(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 1 LDYGQHVVAGTPGR 14 0 I3L3H2;P38919 I3L3H2 EIF4A3 Eukaryotic initiation factor 4A-III;Eukaryotic initiation factor 4A-III, N-terminally processed 1 LDYGQHVVAGT(1)PGR 74.325 0.039406000000000004 9488300.0 91716.0 109540.0 103760.0 97475.0 122260.0 103220.0 97835.0 99679.0 101500.0 70772.0 True False 90408.11302134542 109286.36686011753 95229.25332518277 104643.63666706755 115068.90717240832 98805.52121757227 102900.41758966853 104310.45023608021 90068.00115761612 83004.84590223785 1.0891907820397262 1.3166263447899627 1.147273418678985 1.260693102066783 1.3862914378268365 1.1903584681543085 1.239691688734215 1.256679042075879 1.0850932879713695 1.0 16.340907944383083 -8.423267459984535 3.1747101366128283 1.0018641646949193 1.2402380438810154 0.5019585716778672 0.07891902744175576 0.1816559695782088 3.47833669084001 0.07317499897032294 0.01956430056973695 3.773397349145268e-09 8.423267459984535 0.2383738791860961 LDYVPS(ph)SASR ddPTM_PC-9_AZD4547_30min_R2 1 LDYVPSSASR 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LDYVPS(0.825)S(0.103)AS(0.072)R 93.839 0.0065373 184490000.0 37082.0 38212.0 63494.0 79241.0 68395.0 49869.0 64691.0 55250.0 51189.0 56421.0 True False 48873.30464648466 50563.28172361265 62652.02807375738 60973.21171124597 58899.53483363624 46750.68354656001 70448.37367692735 46712.38201869585 53894.74603558528 54445.71796321582 0.897651945365181 0.9286916146054646 1.150724619263646 1.1198899379459042 1.0818028861962932 0.8586659391312523 1.2939194543182095 0.8579624581359234 0.989880344162184 1.0 15.732530968139798 -10.413138248718225 14.877342486467024 0.9999958140903343 1.0243889560873174 0.0009640762457303609 0.13512852367679162 0.0 0.0 0.12865451635088082 0.031203303536908006 3.862440046454212e-11 10.413138248718225 0.02439314199698306 LDYVPS(ph)SASR ddPTM_PC-9_Lapatinib_30min_R1 1 LDYVPSSASR 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LDYVPS(0.911)S(0.068)AS(0.021)R 105.13 0.0025043 175870000.0 78258.0 71660.0 76590.0 75269.0 70192.0 63320.0 57901.0 62636.0 69835.0 50380.0 True False 77142.02656924052 71494.0756727774 70293.06584594988 80804.53335002327 66063.44456278167 60611.95120612937 60898.830468231165 65546.29722396012 61969.44690484847 59088.11587286968 1.3055421624073191 1.2099569366300258 1.1896311941505813 1.3675259763549963 1.1180496041694692 1.0257892016143868 1.03064431093483 1.1092974662618362 1.048763291728206 1.0 15.850580376359597 -6.470272811703612 5.760910292914691 1.0508663589308642 1.25799205976401 0.798524108929736 0.05327622004731705 0.0974190278295785 7.344231216200775 0.016803330574377807 0.018760191060697998 3.38631370513083e-07 6.470272811703612 0.20712570083314574 LDYVPS(ph)SASREVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LDYVPSSASREVR 13 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LDYVPS(0.333)S(0.333)AS(0.333)REVR 54.812 0.03768 6443600.0 15094.0 0.0 8009.9 35693.0 33895.0 54606.0 27232.0 72490.0 39292.0 18065.0 True False 17649.116079910964 0.0 8200.886393714914 33693.236928267295 27253.518067293397 51742.36523163091 24652.38781739339 70587.21430950398 39866.5711668391 21340.04149753869 0.8270422567803616 0.0 0.3842957097651748 1.5788740116626951 1.2771070792171024 2.4246609472431793 1.1552174263689572 3.307735569194903 1.8681580901066768 1.0 14.381275361158604 -5.998345614916707 1.4081319568200077 2.0192302669019524 0.3077424983842643 0.46797570421826773 0.6721720481014156 0.3320549339198823 1.3344441192738818 0.23028563963057005 0.41386356535559843 1.0038166272738037e-06 5.998345614916707 -1.7114877685176881 LDYVPSS(ph)ASR ddPTM_PC-9_AZD4547_30min_R2 1 LDYVPSSASR 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LDYVPS(0.139)S(0.521)AS(0.341)R 107.09 0.002222 178050000.0 64114.0 60884.0 88736.0 91631.0 85022.0 74260.0 79525.0 81118.0 60900.0 79253.0 True False 84500.91834595549 80563.56234848821 87559.30266092757 70506.88863483765 73218.16288654738 69616.51046075813 86602.57093966147 68583.07700620037 64119.0496701859 76478.37659273593 1.1048994776123628 1.0534162195610766 1.144889661128661 0.9219192636671963 0.9573707778402527 0.9102770425094306 1.1323798281027733 0.8967642889626206 0.8383944917088637 1.0 16.222764279091088 -5.765740241474005 24.997913961000943 0.9528378662999498 1.0963032376584652 0.4496418698196726 0.07600190942925371 103.88492130172442 603815.5434989082 0.021750585909924597 0.03357721600441817 1.714982759624586e-06 5.765740241474005 0.14346537135851534 LDYVPSS(ph)ASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LDYVPSSASR 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LDYVPS(0.275)S(0.715)AS(0.01)R 111.5 0.0015869999999999999 99743000.0 46977.0 58070.0 60280.0 69711.0 63692.0 56655.0 59613.0 55378.0 53010.0 41759.0 True False 54929.27826195688 63834.805828739816 61717.30381317309 65805.3186761112 51212.00981684764 53683.912064572556 53966.025079254985 53924.38617784111 53785.17096493281 49329.57613593786 1.1135161208478233 1.294047320674919 1.2511217133327535 1.3339931909159533 1.0381603457471913 1.0882702887337896 1.0939892313394388 1.0931451352681665 1.0903229903438991 1.0 15.590165270587356 -6.270713433716824 24.947834490157916 1.0743534264471861 1.251657434950956 0.6865312388975839 0.059737066209509804 370.2046825161943 995873.4089951202 0.017985850918495628 0.020662410095984875 5.361503159888841e-07 6.270713433716824 0.17730400850376982 LDYVPSS(ph)ASR ddPTM_PC-9_Lapatinib_30min_R1 1 LDYVPSSASR 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LDYVPS(0.334)S(0.663)AS(0.004)R 96.604 0.0054667000000000006 168850000.0 72209.0 59799.0 68127.0 61930.0 55404.0 59274.0 47141.0 45252.0 54929.0 45954.0 True False 71179.28641849115 59660.53908953959 62525.86103782506 66484.53879242389 52145.24564845501 56738.989194442685 49581.73031731548 47354.573120547895 48742.31759198715 53897.087670143985 1.320651810615744 1.1069343756506576 1.16009721008471 1.2335460349790413 0.9674965365028546 1.052728294739995 0.9199333852834691 0.8786109819210086 0.9043590238176766 1.0 15.717919698587425 -6.493609551739468 1.0954976677019346 0.9172355011711485 1.2097943182008357 0.7315215424040438 0.07308010667787018 0.25317494432774823 0.6445847788110303 0.03403873552919863 0.04027672628155391 3.209153186142581e-07 6.493609551739468 0.2925588170296872 LDYVPSS(ph)ASREVR ddPTM_PC-9_AZD4547_30min_R2 1 LDYVPSSASREVR 13 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LDYVPS(0.286)S(0.399)AS(0.315)REVR 72.797 0.010739 12676000.0 31170.0 9812.5 35310.0 167760.0 97542.0 32482.0 22499.0 23837.0 18483.0 49789.0 True False 41081.41162372378 12984.198731104076 34841.76632885585 129085.5238661628 83999.97699747866 30450.89540514871 24501.367413661676 20153.539369767463 19459.973646207633 48045.902264592136 0.855045064977354 0.27024570502598094 0.7251766474689102 2.686712451673398 1.748327600028925 0.633787565013422 0.5099574835483562 0.41946427103773626 0.4050287897402821 1.0 15.552125771325864 -6.89886727862481 8.280695813952017 0.540672131805656 1.2509937863779563 0.2169711269306679 0.6284364608071875 0.4406063327762607 32.272305526208164 0.251208582678117 0.22158106082057613 1.2622132108657828e-07 6.89886727862481 0.7103216545723003 LDYVPSS(ph)ASREVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LDYVPSSASREVR 13 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LDYVPS(0.291)S(0.355)AS(0.355)REVR 59.673 0.028533 6354900.0 19465.0 2416.1 17642.0 40573.0 35657.0 52958.0 23497.0 71343.0 52443.0 18887.0 True False 22760.040048725772 2655.954440551374 18062.652187657583 38299.826349440766 28670.266815916213 50180.78925276911 21271.194056451684 69470.32184415673 53209.87966259141 22311.06359059026 1.0201234896898805 0.11904203624212377 0.8095827486805939 1.7166293392482554 1.2850246560189968 2.2491437509923538 0.953392202486611 3.113716276325616 2.384910044585808 1.0 14.445471669478229 -5.963283762910295 0.9794440373279001 2.0325893070101833 0.4605705773535711 0.3808966687015095 0.6672841976564117 0.583486054988274 1.1254964329973562 0.28007204853833595 0.6382888025622955 1.088218831598772e-06 5.963283762910295 -1.5720187296566122 LDYVPSSAS(ph)R ddPTM_PC-9_AZD4547_30min_R2 4 LDYVPSSASR 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LDYVPSSAS(1)R;LDYVPSS(0.001)AS(0.999)R;LDYVPSSAS(1)R;LDYVPSSAS(1)R 178.53 0.00012173 82736500.0 238474.0 226993.0 315313.0 399631.0 376649.0 334872.0 252379.0 359120.0 287152.0 292023.0 True False 314303.77143265615 300364.0481599502 311131.7435981454 307502.24718740204 324357.78778498806 313932.4009024377 274840.2420770937 303626.25575663376 302330.26848757296 281799.3636548837 1.11534592327036 1.0658790859719698 1.1040895889998699 1.091209870736246 1.1510238475280063 1.1140280688742326 0.9753046937809527 1.0774554343156049 1.0728564627201687 1.0 18.10430882826683 -7.223182093738183 24.995805664755757 1.0378587393791407 1.1062241737386165 0.5267308379510707 0.03485378669186399 490.8496379092294 320702.1941452253 0.01351934214662154 0.010471918172016988 5.981607418538869e-08 7.223182093738183 0.06836543435947573 LDYVPSSAS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LDYVPSSASR 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LDYVPS(0.001)S(0.003)AS(0.996)R;LDYVPS(0.001)S(0.001)AS(0.998)R;LDYVPSSAS(1)R 132.03 0.00016013 103098000.0 208481.0 216221.0 251732.0 222080.0 275994.0 240545.0 234151.0 229405.0 204978.0 159100.0 True False 243772.71561255568 237685.99192519285 257734.24557892582 209637.57759307427 221914.95693950623 227930.39674472887 211970.5221735631 223383.36182468888 207975.41546972265 187943.57056509273 1.2970526998055887 1.2646667891353711 1.3713384544307232 1.115428300966901 1.1807531179293402 1.2127597451692929 1.1278413064954986 1.188566127338322 1.1065843585093114 1.0 17.51994003694457 -1.5228787453202908 0.07044189690445282 0.7821140170381398 2.154392947632456 0.6846337310533406 0.05696175382548145 146.45381311220848 0.7643481523237122 2.5868526334489683 19.915231257329307 0.02999999999724013 1.5228787453202908 1.3722789305943164 LDYVPSSAS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 4 LDYVPSSASR 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LDYVPS(0.029)S(0.001)AS(0.97)R;LDYVPS(0.004)S(0.007)AS(0.989)R;LDYVPSSAS(1)R;LDYVPSSAS(1)R 152.67 0.00011719 89913900.0 296428.0 252382.0 299959.0 253554.0 285144.0 219658.0 241356.0 218501.0 274718.0 221317.0 True False 292200.88236176263 251797.62498530434 275297.5288952238 272201.2069913481 268372.3905346733 210263.7393878072 253852.23271602206 228653.35413711777 243776.36593121168 259571.34856363432 1.1257054523878975 0.9700516885960384 1.0605851933143313 1.0486565967222594 1.0339060609722162 0.8100421735731774 0.9779670757991604 0.8808882621383116 0.9391497454560148 1.0 17.985771622156122 -6.61705737564085 10.664524288944584 0.9177624074818661 1.0455055322239668 0.5240594786000281 0.060144248019259335 0.2865030670025097 30.22571683880897 0.01842155193780442 0.018416697978648314 2.415141743448227e-07 6.61705737564085 0.1277431247421007 LDYVPSSAS(ph)REVR ddPTM_PC-9_AZD4547_30min_R2 1 LDYVPSSASREVR 13 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LDYVPS(0.013)S(0.194)AS(0.793)REVR 84.62 0.0040093 13988000.0 26499.0 12533.0 33760.0 188800.0 105850.0 39609.0 21697.0 35959.0 18555.0 54116.0 True False 34925.13078655943 16584.047153827007 33312.32034160786 145275.07693092249 91154.55460399727 37132.24296849132 23627.99096734155 30402.362805615998 19535.779419216728 52221.41531162845 0.6687894339543579 0.31757176734607073 0.6379053524845776 2.781906159838859 1.7455397189072228 0.7110539372957758 0.4524578820076553 0.582181900360064 0.37409517345782434 1.0 15.672353937839768 -6.952280244891739 11.864438795441236 0.5693995540219934 1.2328150297141172 0.17330095393546363 0.664054767966355 1.522953762868186 374.79399834394104 0.26408497150065846 0.23285262086380978 1.1161427821317138e-07 6.952280244891739 0.6634154756921238 LDYWEDDLR ddPTM_PC-9_Lapatinib_30min_R1 1 LDYWEDDLR 9 0 E9PEM5;A0A494C1L5;P50851-2;P50851;A0A494BZW2;H0YAC6;Q5T321;A0A0D9SF28;F5GXV7;Q8NFP9 E9PEM5 LRBA;NBEA Lipopolysaccharide-responsive and beige-like anchor protein;Neurobeachin 0 117.81 0.0084574 793440.0 5781.2 8623.6 9963.9 7851.3 8859.8 9407.7 6817.6 7617.5 8626.0 7141.4 False True 5698.7590278577645 8603.632584032403 9144.706603766264 8428.71079316901 8338.683983036992 9005.354601419827 7170.5819692270015 7971.436859050955 7654.449044193072 8375.781474682643 0.6803853521111223 1.027203564233198 1.0918033894995758 1.006319328966062 0.9955708620434064 1.075165896894539 0.8561090079655754 0.9517245504967036 0.9138787905737593 1.0 13.032008087305178 -10.398989324675043 14.848300999385344 0.9999999994291827 0.9646582584354727 0.007725039845847936 0.11415814988560746 0.0 0.0 0.11011458221059853 0.02670670902206219 3.990347108516129e-11 10.398989324675043 -0.035341740993710014 LEAALGEAK ddPTM_PC-9_Lapatinib_30min_R1 1 LEAALGEAK 9 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 126.07 0.0064796 8815700.0 77813.0 66933.0 70945.0 72761.0 69163.0 59805.0 72422.0 64166.0 73083.0 69255.0 False True 76703.3723508434 66778.02075085112 65112.17595561957 78112.08666358063 65094.96831968972 57247.279562264164 76171.65679643252 67147.38660949958 64851.62294189221 81225.63447351311 0.9443246931589759 0.822129875422848 0.8016210199854088 0.9616679164143953 0.8014091701667969 0.7047932581053823 0.9377785386369787 0.8266772804513541 0.7984132517061432 1.0 16.30964748739588 -10.662540097370208 4.142987963303772 1.0000366713759121 0.8427212374255774 0.27116455201404455 0.07653242308192208 36025541.88199473 1.188603237783691 14737.3894558083 0.01831625817812434 2.1750032119073785e-11 10.662540097370208 -0.15731543395033476 LEAEIATYR ddPTM_PC-9_AZD4547_30min_R2 2 LEAEIATYR 9 0 P05783;F8VZY9;CON__P05784 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ; 129.42 0.005982899999999999 15172300.0 74987.2 60360.0 96814.0 109739.0 99946.0 89173.0 80019.0 106547.0 83528.0 97137.0 False True 98831.56976934578 79870.18959586677 95530.18310285626 84440.36900064889 86070.22309353904 83596.9982132668 87140.53598265673 90082.60935648857 87943.11955420823 93736.2631962018 1.0543579016210498 0.8520735398709932 1.0191379498764481 0.9008292641654017 0.9182169222319352 0.8918319907663457 0.929635266132389 0.9610219810868108 0.9381974121384826 1.0 16.51631966235695 -9.12125797332853 1.1020574828356764 0.9999928760550503 0.9358022700959453 0.08579570643928247 0.05666837686075609 6.306105665817016 9.533810885374674 0.05160046233541953 0.01568530371566503 7.563834655829776e-10 9.12125797332853 -0.06419060595910497 LEAEIATYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LEAEIATYR 9 0 P05783;F8VZY9;CON__P05784 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ; 104.2 0.012527 6289200.0 35594.0 36821.0 40135.0 41342.0 50246.0 39641.0 47745.0 35008.0 30952.0 28953.0 False True 41619.361186454895 40476.34553848852 41091.97061283509 39025.74177257242 40400.656993929006 37562.15617600782 43222.24795613422 34089.077094042084 31404.614444568946 34201.949708178116 1.2168710129558253 1.183451407999998 1.20145111502253 1.1410385111244368 1.1812384188223253 1.0982460501959699 1.2637363754090087 0.9966998193056508 0.9182112339361668 1.0 15.061790948933849 -7.8708122667798195 6.0376879907048195 0.9595865293493628 1.1789226319426285 0.8203136961526074 0.04559416331368931 0.07857471897809357 3.8504103388157414 0.024149906475567365 0.01142927135911301 1.346442257179403e-08 7.8708122667798195 0.21933610259326564 LEAEIATYR ddPTM_PC-9_Lapatinib_30min_R1 4 LEAEIATYR 9 0 P05783;F8VZY9;CON__P05784 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ;;; 123.35 0.0069158 103964000.0 339472.0 428479.0 411057.0 408620.0 441007.0 419884.0 389769.0 370127.0 350102.0 383543.0 False True 334631.06702846015 427486.8832011718 377261.48018590524 438671.2779163607 415067.8353131219 401926.5401174101 409949.33166563575 387324.45163504407 310669.82602249953 449837.8965110762 0.7438925657972453 0.9503131828526278 0.8386609556729867 0.9751763497888388 0.9227053534892693 0.8934919517335811 0.911326802043993 0.8610311728716415 0.6906261754112796 1.0 18.77904568025145 -9.814436204182334 8.567626614915644 1.0000085508151824 0.8739523322775045 0.17830495228699794 0.08495248457965618 0.0 0.0 0.08096533184972166 0.019636977366446363 1.5330763915377556e-10 9.814436204182334 -0.1260562185376779 LEAEIATYRR ddPTM_PC-9_Lapatinib_30min_R1 1 LEAEIATYRR 10 1 P05783;F8VZY9;CON__P05784 P05783 KRT18 Keratin, type I cytoskeletal 18 0 86.882 0.0069494 2401400.0 40737.0 11613.0 13049.0 12261.0 12447.0 12343.0 12065.0 9374.4 19542.0 9026.2 False True 40156.08290974913 11586.110812000596 11976.16159059665 13162.714841496982 11714.891931743543 11815.118662938328 12689.666665501618 9809.968846929729 17340.97417361709 10586.366643344512 3.7931883773357358 1.0944369491760053 1.1312815807419518 1.2433647241730645 1.1066017573752291 1.1160692861857673 1.1986800658826056 0.9266605982419008 1.6380477606563058 1.0 13.369919905135443 -4.7605875685316565 24.99999978627002 1.1590025356356788 3.7931914468461896 0.9501517415802819 0.18082223832192706 3.7563055202254767 110180.78196310112 0.041226654344783654 0.24204342160405992 1.7354513016104658e-05 4.7605875685316565 2.6341889112105106 LEAIETQDPSLGCGLPLNCT(ph)PIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LEAIETQDPSLGCGLPLNCTPIK 23 0 K7ES22;Q9NVP2 K7ES22 ASF1B Histone chaperone ASF1B 1 LEAIETQDPSLGCGLPLNCT(1)PIK;LEAIETQDPSLGCGLPLNCT(1)PIK 118.76 4.4002999999999994e-08 6021100.0 39667.0 52632.0 49696.0 44619.0 55196.0 33038.0 50766.0 30823.0 31430.0 35534.0 True False 46381.83964103801 57856.95712722973 50880.941113129535 42119.14208674978 44380.740027801294 31305.429119924986 45957.07696598825 30013.928909668026 31889.604290281794 41976.03291301078 1.104960055114251 1.3783331370815783 1.2121426819578898 1.003409306783125 1.0572876221955971 0.7457929429586863 1.0948408836353738 0.7150253805991511 0.7597098171799217 1.0 15.357278205846802 -6.098373229244923 1.2037166834089394 0.8584350528424853 1.2606503019206474 0.5579552263472154 0.13536243404523784 0.33195261623449157 0.9819008137461755 0.05173766807331528 0.08954208687308889 7.973091915383798e-07 6.098373229244923 0.4022152490781621 LEAIETQDPSLGCGLPLNCT(ph)PIK ddPTM_PC-9_Lapatinib_30min_R1 2 LEAIETQDPSLGCGLPLNCTPIK 23 0 K7ES22;Q9NVP2 K7ES22 ASF1B Histone chaperone ASF1B 1 LEAIETQDPSLGCGLPLNCT(1)PIK;LEAIETQDPSLGCGLPLNCT(1)PIK 113.71 7.9285e-08 6171400.0 25823.4 59788.0 58988.0 58458.0 66024.0 60182.0 54111.0 54162.0 57094.0 46915.0 True False 25455.15358056842 59649.56455936379 54138.23434026481 62757.19633017135 62140.59812817837 57608.1561510941 56912.602812843594 56678.5642481021 50663.472493526446 55024.19523969194 0.4626174625486615 1.0840606445859533 0.9838987031874292 1.1405381951847462 1.1293322484315587 1.046960448946979 1.034319585500988 1.0300662099864166 0.9207489954706349 1.0 15.747778519580942 -4.759175120934399 24.99990798680047 1.046090355307042 0.4626167082764415 0.8842649756505488 0.06276149504493193 19.117523709495163 211030.32676817614 0.016136006831823365 0.10447166226623296 1.7411046647058805e-05 4.759175120934399 -0.5834736470306005 LEAIIT(ph)PPPAK ddPTM_PC-9_AZD4547_30min_R2 2 LEAIITPPPAK 11 0 D6RCF2;O75367-2;O75367-3;O75367 D6RCF2 H2AFY Histone H2A;Core histone macro-H2A.1 1 LEAIIT(1)PPPAK;LEAIIT(1)PPPAK 98.105 0.012504000000000001 14833600.0 179623.0 193548.0 235283.0 231299.0 217672.0 211817.0 231131.0 292810.0 197718.0 227070.0 True False 236739.3776095012 256108.60596257172 232162.99368881856 177976.5890839272 187452.00009221866 198572.04950533767 251701.21123992364 247562.94260442167 208168.96983070273 219120.34841472897 1.080408001001462 1.168803389623291 1.059522747971374 0.8122321380535183 0.8554750914206669 0.9062236845731025 1.1486893529556137 1.1298035275841174 0.9500211702689584 1.0 17.74136393956774 -5.528372564982411 24.993816145719578 0.9738185120101612 1.1219950678201593 0.2707263757775873 0.1023561454638488 204.47213093263306 930231.2169599554 0.03170371543801511 0.05513717980351656 2.9622890622746724e-06 5.528372564982411 0.1481765558099981 LEAIIT(ph)PPPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LEAIITPPPAK 11 0 D6RCF2;O75367-2;O75367-3;O75367 D6RCF2 H2AFY Histone H2A;Core histone macro-H2A.1 1 LEAIIT(1)PPPAK;LEAIIT(1)PPPAK 88.803 0.023543 12662300.0 88501.0 136110.0 117462.0 80179.0 110454.0 65723.0 89723.0 70108.0 68440.0 60861.0 True False 103482.47132557307 149622.1012803472 120262.73955711594 75686.83057382515 88811.33160067354 62276.37018127098 81223.78790173266 68267.73928556622 69440.80552424086 71894.61752458902 1.4393632637405789 2.081130777685468 1.6727641609051513 1.0527468283413448 1.235298756131483 0.8662174210742764 1.12976173597353 0.9495528543874323 0.9658693225607756 1.0 16.133596145189628 -5.731914451154662 4.273917719294265 1.0282997534395943 1.7859080742687956 0.776489010633435 0.17297065707089782 0.08376290039512625 3.409913531358375 0.045958900748019296 0.07876771032574363 1.8538967745171251e-06 5.731914451154662 0.7576083208292013 LEAIIT(ph)PPPAKK ddPTM_PC-9_Lapatinib_30min_R1 1 LEAIITPPPAKK 12 1 D6RCF2;O75367-2;O75367-3;O75367 D6RCF2 H2AFY Histone H2A;Core histone macro-H2A.1 1 LEAIIT(1)PPPAKK 62.376999999999995 0.044081999999999996 17889000.0 48978.0 58657.0 76007.0 68484.0 68434.0 69018.0 58955.0 56838.0 70211.0 59103.0 True False 48279.56473853482 58521.183320375334 69757.99785550451 73520.54181592698 64408.84666642054 66066.26102881617 62007.40143096955 59478.900977320365 62303.09782539296 69318.87480020279 0.696485118630252 0.8442315817885165 1.0063348266481158 1.0606136067244978 0.9291675153710388 0.9530775163220465 0.8945240615877417 0.8580476983903144 0.8987898029933211 1.0 16.080960616082407 -4.909018414985472 3.1681288759283617 0.9459067293956231 0.689797021029047 0.6498625896899763 0.05770323155707496 0.19680235262287804 3.458198974225664 0.016690915278175407 0.10714650843616928 1.2330525481386813e-05 4.909018414985472 -0.2561097083665761 LEAKSS(ph)EEMGHWLGLLLS(ph)ES(ph)GSK ddPTM_PC-9_Lapatinib_30min_R1 1 LEAKSSEEMGHWLGLLLSESGSK 23 1 Q8N4X5-2;Q8N4X5;Q8N4X5-4 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 3 LEAKS(0.137)S(0.863)EEMGHWLGLLLS(0.959)ES(0.72)GS(0.32)K 47.75 0.039097 0.0 3562.3 3074.0 3162.8 3071.2 4846.8 3776.5 4428.2 5996.8 4525.5 5227.2 True False 3511.500948754187 3066.8823418659977 2902.7667927610637 3297.0662932228647 4561.72075317543 3614.987898451478 4657.470528650991 6275.433220394716 4015.790534372333 6130.714555193817 0.5727718877042342 0.5002487579963737 0.4734793581772452 0.537794781267325 0.7440765202990625 0.589651967304355 0.7596945652452985 1.0236055135005913 0.6550281371312967 1.0 12.581839519288694 -7.137915584630682 0.5906687898979361 0.9393438161032878 0.49060207008639695 0.6372477576478863 0.11204392726716862 0.5119455007577354 0.3720905568515695 0.09738788197918201 0.0806118117788913 7.279212794453877e-08 7.137915584630682 -0.4487417460168908 LEAPS(ph)PCSLPQSDPR ddPTM_PC-9_AZD4547_30min_R2 1 LEAPSPCSLPQSDPR 15 0 O60248 O60248 SOX15 Protein SOX-15 1 LEAPS(0.979)PCS(0.021)LPQSDPR 172.26 0.00010369 19437000.0 35985.0 38249.0 55999.0 80505.0 62944.0 72196.0 41202.0 88365.0 57976.0 54276.0 True False 47427.481465502104 50612.2412500382 55256.41667090337 61945.816039851285 54205.312092527216 67681.57270704139 44868.89818114975 74710.21967569336 61040.49299965016 52375.81376032862 0.9055225696832119 0.9663284943244888 1.054998723719241 1.1827179683224576 1.034930213028677 1.29222952060949 0.856672096522825 1.426425945715456 1.1654328327760415 1.0 15.676613133614332 -5.295653994327505 1.569540406071935 1.1474158492520512 0.8975282495320246 0.2241490784604857 0.14856199227887315 0.7095578733089245 2.94012625044667 0.04258630204079606 0.19981865195361656 5.062278168837607e-06 5.295653994327505 -0.2498875997200266 LEAPS(ph)PCSLPQSDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LEAPSPCSLPQSDPR 15 0 O60248 O60248 SOX15 Protein SOX-15 1 LEAPS(0.97)PCS(0.012)LPQS(0.018)DPR;LEAPS(0.766)PCS(0.234)LPQSDPR;LEAPS(0.698)PCS(0.296)LPQS(0.005)DPR 152.94 6.0274e-05 17255800.0 48818.0 56573.0 57870.0 53574.0 65024.0 50258.4 51063.0 50504.7 53250.0 40282.9 True False 57081.92320054945 62189.1935620681 59249.84027319719 50572.42246925148 52283.013978689625 47622.76102914332 46225.942975894475 49179.005139152934 54028.68051089737 47585.87089073905 1.199556131516729 1.3068835853579195 1.2451141308149964 1.0627613096620592 1.0987087763663208 1.0007752330200907 0.9714216028962237 1.0334791445148046 1.1353933320869871 1.0 15.53824565430635 -5.776738892024932 3.9152944753257257 1.0396470611852036 1.2602017513687895 0.7749648442842954 0.05129475208404389 0.09745922205657087 3.2732710136119105 0.01515947579578673 0.025111631258545444 1.6720956150610117e-06 5.776738892024932 0.22055469018358598 LEAPS(ph)PCSLPQSDPR ddPTM_PC-9_Lapatinib_30min_R1 3 LEAPSPCSLPQSDPR 15 0 O60248 O60248 SOX15 Protein SOX-15 1 LEAPS(0.955)PCS(0.041)LPQS(0.005)DPR;LEAPS(0.998)PCS(0.002)LPQSDPR;LEAPS(0.969)PCS(0.03)LPQSDPR 155.56 1.7107e-05 18186000.0 49791.6 56266.1 79314.0 62032.3 59905.7 63581.0 59580.8 48709.2 64799.5 52927.6 True False 49081.562653338886 56135.81930242889 72793.10908089367 66594.36227568662 56382.1645051377 60861.78884455006 62665.60229290664 50972.407253677025 57501.09794101421 62076.06513840605 0.7906680705986381 0.9043069849428654 1.172643738268408 1.0727864616935125 0.9082754259540595 0.9804388971635265 1.0094970123055664 0.8211281939347785 0.9263006250929179 1.0 15.921749490791882 -7.7282548200880745 24.96129123516519 0.9052854889914673 0.9828577522758294 0.06201610409215652 0.10487419719641529 454.89061407789507 342166.9395110505 0.05238418874084436 0.030241516575934112 1.869584849039254e-08 7.7282548200880745 0.07757226328436206 LEAPSPCS(ph)LPQSDPR ddPTM_PC-9_AZD4547_30min_R2 1 LEAPSPCSLPQSDPR 15 0 O60248 O60248 SOX15 Protein SOX-15 1 LEAPS(0.064)PCS(0.934)LPQS(0.002)DPR 116.58 0.00014214 15402000.0 29914.0 33238.0 48645.0 65325.0 47836.0 51292.0 35097.0 62937.0 39715.0 60293.0 True False 39426.02975014675 43981.5334954841 47999.93551592166 50265.33051118917 41194.79710946447 48084.70313160791 38220.56500810187 53211.53279838301 41814.25382022057 58182.16042176092 0.6776309003369507 0.7559281603959555 0.8249940388595304 0.8639302863079874 0.7080314105018529 0.8264509736840844 0.6569120969562151 0.9145678402564297 0.7186782600905529 1.0 15.828289247178677 -14.522878741019555 0.35366990773321294 3.6423611113882 0.7696545971973633 0.4192550244402873 0.08018724548333349 439.3360933294598 3.5659592651953695 881.5060117080135 0.05781355544691579 3.0000000294324404e-15 14.522878741019555 -2.872706514190837 LEAPSPCS(ph)LPQSDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LEAPSPCSLPQSDPR 15 0 O60248 O60248 SOX15 Protein SOX-15 1 LEAPS(0.095)PCS(0.828)LPQS(0.077)DPR 93.23700000000001 0.0033398000000000004 9233000.0 22203.0 19475.0 21323.0 18201.0 24535.0 19182.0 20810.0 17997.0 17219.0 11807.0 True False 25961.529370760745 21408.34929420884 21831.421187927823 17181.256978438156 19727.542875971172 18176.062152018912 18838.726148647038 17524.597819397706 17470.795299852445 13947.515635839427 1.8613730250317986 1.5349220501462006 1.5652551865100601 1.2318507056761658 1.4144126732706026 1.3031756067950802 1.3506868635615072 1.256467336330969 1.2526098379097441 1.0 13.767720548267244 -1.5228787452803376 0.27731033773269725 1.1578244060542144 5.934773671984549 0.803625923644626 0.0986660548975506 22.752996375256505 0.3199894611016904 0.10822856111925404 52.49061805969118 0.029999999999999995 1.5228787452803376 4.776949265930334 LEAPSPCS(ph)LPQSDPR ddPTM_PC-9_Lapatinib_30min_R1 1 LEAPSPCSLPQSDPR 15 0 O60248 O60248 SOX15 Protein SOX-15 1 LEAPS(0.15)PCS(0.849)LPQS(0.001)DPR 187.08 3.3632e-07 15940000.0 35205.0 38736.0 62002.0 34207.0 40858.0 39198.0 37252.0 30922.0 51435.0 30030.0 True False 34702.97024419369 38646.309171932764 56904.43489464126 36722.69689120687 38454.812769918644 37521.5929150009 39180.72628456414 32358.74900631094 45641.84866543828 35220.645487540234 0.9853019376510382 1.0972629444172 1.6156556504556951 1.0426469016360875 1.0918258946594985 1.0653295076115132 1.1124363492550082 0.918743781051891 1.2958833670889047 1.0 15.104133729182506 LEAS(ph)IER ddPTM_PC-9_AZD4547_30min_R2 2 LEASIER 7 0 Q9UBI6 Q9UBI6 GNG12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 1 LEAS(1)IER;LEAS(1)IER 90.601 0.015819 6069200.0 20421.9 24312.0 29209.0 36905.0 37115.0 23733.0 24618.0 33097.0 25367.0 22825.0 True False 26915.63939809194 32170.37855292766 28821.669575178446 28397.122426566177 31962.222901533878 22248.971758216696 26808.954308614746 27982.619143398657 26707.8478322431 22025.9036973893 1.221999322610414 1.4605701992940598 1.308535167099393 1.2892602644917606 1.4511197061722518 1.0101275327401815 1.2171557034362397 1.270441364306673 1.212565359368603 1.0 14.426913592020712 -6.751783562884556 24.999996330254554 1.1636541719285638 1.3473788558826214 0.4783084772049371 0.10544786451032662 197.21522443470147 510611.6844887813 0.03436219817994394 0.033949068243465164 1.7709913383035486e-07 6.751783562884556 0.1837246839540576 LEAS(ph)YSDSPPGEEDLLVHVAEGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LEASYSDSPPGEEDLLVHVAEGSK 24 0 Q7Z3C6;C9JS65;C9JFV2;F2Z3I6;C9JX27;C9IYZ9;C9JKV7;C9JDK4;C9JXG2;Q7Z3C6-3 Q7Z3C6 ATG9A Autophagy-related protein 9A 1 LEAS(0.426)Y(0.009)S(0.306)DS(0.259)PPGEEDLLVHVAEGSK 65.15100000000001 0.00075931 2102600.0 7749.2 8755.4 8394.2 11898.0 11203.0 9927.9 8879.8 7670.6 9118.0 7249.9 True False 9060.986506323441 9624.578249577198 8594.349563180782 11231.393633836457 9007.852571408399 9407.263446930898 8038.641059815281 7469.254877672509 9251.33350043873 8564.24947982318 1.0580012326439745 1.1238087204549663 1.003514620099346 1.3114276575311001 1.0517970772138667 1.0984340740065786 0.938627614568422 0.8721435422064235 1.0802269973842162 1.0 13.064111107249277 -7.2226697990991395 6.400509033894808 0.9620775980231759 1.1111148600095828 0.3445024167147266 0.09076226076227796 0.22050991541324036 26.74278089075199 0.03467679997795833 0.02636398144999749 5.988667497830674e-08 7.2226697990991395 0.14903726198640688 LEASDCDHQQNS(ph)PTLERPGR ddPTM_PC-9_AZD4547_30min_R2 3 LEASDCDHQQNSPTLERPGR 20 1 B1AN62;Q9HAN9 B1AN62 NMNAT1 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 1 LEAS(0.001)DCDHQQNS(0.994)PT(0.005)LERPGR;LEAS(0.001)DCDHQQNS(0.865)PT(0.135)LERPGR;LEASDCDHQQNS(0.977)PT(0.023)LERPGR 52.644 0.016486 37773000.0 85015.6 67863.5 139656.0 145975.0 118172.0 128045.0 97629.0 138003.0 98757.0 131143.0 True False 112048.79236566718 89799.04923192672 137804.07019039057 112322.71904126795 101765.85759719943 120038.32590826486 106317.79186756631 116677.80734345861 103977.09340358869 126551.72348682272 0.8853991812868066 0.7095837714235247 1.0889150016573224 0.8875637245111373 0.8041443829707768 0.9485317354904608 0.8401133460551939 0.9219772289834343 0.82161736354713 1.0 16.949367629842428 -11.365912319157966 2.690388450406081 1.0453265671708658 0.8801284233534078 0.12820493239500497 0.0948625527733756 64763632.96488179 42156600.746519476 18874674.98347497 0.02285679047155295 4.306135394032467e-12 11.365912319157966 -0.165198143817458 LEASDCDHQQNS(ph)PTLERPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LEASDCDHQQNSPTLERPGR 20 1 B1AN62;Q9HAN9 B1AN62 NMNAT1 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 1 LEASDCDHQQNS(0.995)PT(0.005)LERPGR;LEAS(0.013)DCDHQQNS(0.951)PT(0.037)LERPGR 77.681 0.0009097000000000002 20428100.0 30097.0 43316.0 50844.0 42278.0 51902.0 43725.0 41986.0 33733.0 47444.0 33455.0 True False 35191.82765715382 47616.126214528864 52056.313786943756 39909.30072712535 41732.17568162447 41431.98402653667 38008.782127683546 32847.544493067886 48137.778744770236 39520.1266703657 0.8904786148760634 1.2048576314466617 1.3172101957349838 1.0098474901157508 1.0559727206774738 1.0483768023346085 0.961757598722085 0.8311598990318704 1.2180572989121137 1.0 15.270299950622231 -5.899300109541827 24.699575900997687 1.0113301640557648 1.147469712852445 0.14110320475784166 0.13390369262909813 19.191560901853133 4679.52409360714 0.03762113387299541 0.05580115358586384 1.2609558779435272e-06 5.899300109541827 0.1361395487966801 LEASDCDHQQNS(ph)PTLERPGR ddPTM_PC-9_Lapatinib_30min_R1 3 LEASDCDHQQNSPTLERPGR 20 1 B1AN62;Q9HAN9 B1AN62 NMNAT1 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 1 LEASDCDHQQNS(0.995)PT(0.005)LERPGR;LEASDCDHQQNS(0.921)PT(0.079)LERPGR;LEASDCDHQQNS(0.965)PT(0.035)LERPGR 69.024 0.0022775 40079500.0 100205.0 95635.0 128892.0 139020.0 140915.0 118420.0 104328.0 112659.0 137957.0 106761.0 True False 98776.05832465338 95413.56303329668 118294.99729750835 149243.99455712474 132626.65674954938 113355.45265050294 109729.59335917552 117893.54842189972 122418.82990838651 125214.4965999097 0.7888548131952048 0.7620009313950753 0.944738832241519 1.1919066770199542 1.059195702980968 0.9052901679004528 0.8763329833109328 0.9415327427989255 0.9776729790284905 1.0 16.934042073145783 -5.3273656028206675 4.767530866063529 0.990028136750391 0.7748464212274849 0.5124483069074587 0.08328491605876137 0.17877944927950937 8.013472623584477 0.025060369517004223 0.05578649206078668 4.705810096378275e-06 5.3273656028206675 -0.2151817155229061 LEASYSDS(ph)PPGEEDLLVHVAEGSK ddPTM_PC-9_AZD4547_30min_R2 2 LEASYSDSPPGEEDLLVHVAEGSK 24 0 Q7Z3C6;C9JS65;C9JFV2;F2Z3I6;C9JX27;C9IYZ9;C9JKV7;C9JDK4;C9JXG2;Q7Z3C6-3 Q7Z3C6 ATG9A Autophagy-related protein 9A 1 LEAS(0.059)Y(0.015)S(0.204)DS(0.721)PPGEEDLLVHVAEGSK;LEAS(0.314)Y(0.042)S(0.296)DS(0.349)PPGEEDLLVHVAEGSK 81.441 0.00016224 2303800.0 23523.3 18778.0 30412.5 38368.2 31248.2 30966.5 26183.4 36393.2 31313.8 30285.6 True False 31003.220084964447 24847.621276195918 30009.21037882552 29523.004272780814 26909.926813194397 29030.15985972349 28513.671876033106 30769.467172539382 32968.98353961027 29225.310362219192 1.0608345882630432 0.850208978732267 1.0268226412958716 1.0101861676359292 0.9207747147822255 0.9933225515802228 0.9756499254459227 1.0528362844117607 1.1280969519567767 1.0 14.834930725286945 -7.805521689267193 4.256008899632099 1.071651096880205 0.973234171163981 0.2726654362159948 0.06211162361336556 0.2436341558856716 9.323789622624851 0.03356698380771731 0.015876106167816262 1.564870165492557e-08 7.805521689267193 -0.09841692571622407 LEASYSDS(ph)PPGEEDLLVHVAEGSK ddPTM_PC-9_Lapatinib_30min_R1 1 LEASYSDSPPGEEDLLVHVAEGSK 24 0 Q7Z3C6;C9JS65;C9JFV2;F2Z3I6;C9JX27;C9IYZ9;C9JKV7;C9JDK4;C9JXG2;Q7Z3C6-3 Q7Z3C6 ATG9A Autophagy-related protein 9A 1 LEAS(0.203)Y(0.004)S(0.17)DS(0.623)PPGEEDLLVHVAEGSK 94.834 0.00099045 0.0 10166.0 13824.0 13618.0 10135.0 11575.0 7936.1 8874.2 9854.9 12857.0 8009.5 True False 10021.03097578392 13791.991377344026 12498.380607000174 10880.361709368888 10894.18125732558 7596.69150295267 9333.662654205924 10312.794631081228 11408.909269787882 9393.931403012102 1.0667558177581267 1.4681809761695421 1.3304739060573352 1.1582330381803907 1.1597041526013732 0.8086807511194771 0.993584289024417 1.0978145558710912 1.2144978263445367 1.0 13.197513343352998 -6.152166205697158 2.1484009495906946 1.030102473867708 1.3008402073648768 0.38772404637798297 0.13713876534368286 0.3182435692543142 2.886243440211903 0.046332630881408834 0.06464520579576324 7.044234325828295e-07 6.152166205697158 0.2707377334971688 LEATINELV ddPTM_PC-9_Lapatinib_30min_R1 1 LEATINELV 9 0 P10599-2;P10599 P10599-2 TXN Thioredoxin 0 100.45 0.017580000000000002 1860300.0 21455.0 19197.0 24206.0 19704.0 25314.0 24839.0 21099.0 17618.0 22336.0 25486.0 False True 21149.04776563488 19152.55052596017 22215.8761178621 21153.097890617126 23825.08028923885 23776.69387253707 22191.402981800115 18436.596597671094 19820.284471492752 29891.221142039623 0.707533749295054 0.6407416557172244 0.7432241062449348 0.7076692447625359 0.7970594501985993 0.7954407001156953 0.7424053663230799 0.616789675806904 0.6630804535321275 1.0 14.86743421599598 -11.588238937999687 2.6101109597402683 1.4232516228983305 0.7142695118913902 0.6944070498638393 0.05717591224334537 11700533.968541931 4021221.0943497904 29518325.71088323 0.016188125081348568 2.5808398861812504e-12 11.588238937999687 -0.7089821110069403 LEAVSHTSDMHR ddPTM_PC-9_AZD4547_30min_R2 1 LEAVSHTSDMHR 12 0 Q01518-2;Q01518;Q5T0R8;Q5T0S3;Q5T0R7;Q5T0R6;Q5T0R5;Q5T0R4;Q5T0R3;Q5T0R2;Q5T0R1;Q5T0R9 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1;Adenylyl cyclase-associated protein 0 78.548 0.009117499999999999 2536300.0 3935.7 4624.8 10853.0 53839.0 22046.0 15823.0 8315.7 23082.0 10936.0 16243.0 False True 5187.170732354501 6119.676157106772 10709.082128775772 41427.250354258125 18985.293441660124 14833.585308653044 9055.781190354526 19515.20727159344 11514.054633713515 15674.337513984412 0.330933969472495 0.3904264631054989 0.6832239078188336 2.6429984882804356 1.2112341861161102 0.9463612286910843 0.5777457058248933 1.2450419199013842 0.7345799861359911 1.0 13.936116847426073 -5.5338501487679395 24.996733324432718 1.2069418631029074 0.4047159614362217 0.29487420224864247 0.5290668568420126 266.4593727480824 607086.5683633911 0.15221424300333805 0.26394471579528295 2.925161516712969e-06 5.5338501487679395 -0.8022259016666857 LEAVSHTSDMHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LEAVSHTSDMHR 12 0 Q01518-2;Q01518;Q5T0R8;Q5T0S3;Q5T0R7;Q5T0R6;Q5T0R5;Q5T0R4;Q5T0R3;Q5T0R2;Q5T0R1;Q5T0R9 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1;Adenylyl cyclase-associated protein 0 64.12100000000001 0.024949000000000002 1668600.0 6064.3 5313.6 11269.0 9592.0 14193.0 15433.0 8567.5 9197.5 11103.0 6320.5 False True 7090.866214615342 5841.099091640981 11537.695697920492 9054.59133768358 11411.983535302998 14623.666311756228 7755.924376671478 8956.075370556784 11265.360370187675 7466.35661694953 0.9497090185215933 0.7823225424808912 1.5452912698716441 1.212718840287988 1.5284541203666082 1.9586080684331018 1.0387830068369082 1.1995241896463147 1.5088162738723125 1.0 12.86618870265447 -5.256642810769094 24.974759680074555 1.389809843115324 0.8660157357858749 0.35770874618528326 0.27163233515152757 413.47177610713806 2152844.6590684406 0.07044800872581533 0.17429156401630913 5.5380540397590154e-06 5.256642810769094 -0.5237941073294492 LEAVSHTSDMHR ddPTM_PC-9_Lapatinib_30min_R1 1 LEAVSHTSDMHR 12 0 Q01518-2;Q01518;Q5T0R8;Q5T0S3;Q5T0R7;Q5T0R6;Q5T0R5;Q5T0R4;Q5T0R3;Q5T0R2;Q5T0R1;Q5T0R9 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1;Adenylyl cyclase-associated protein 0 57.885 0.039336 1088600.0 4164.4 3861.2 8969.8 5090.3 7836.2 9779.9 6041.6 5798.3 11620.0 5384.6 False True 4105.0148923425695 3852.2596286314188 8232.3376684293 5464.6576427430155 7375.290122561957 9361.6364750604 6354.404486224164 6067.710185734836 10311.233235975358 6315.320935471496 0.6500089123397959 0.6099863598371208 1.3035501683200967 0.8653016526918642 1.1678409059366868 1.4823690784230064 1.006188687978333 0.9607920559751927 1.6327330536853437 1.0 12.624640336212234 -5.2539036198108935 24.806193122214125 1.1692435443409086 0.629997549291923 0.4780581986460014 0.2286425739032181 434.03285488637283 1428738.48213544 0.057305750980304444 0.14540369925787275 5.5730941531352495e-06 5.2539036198108935 -0.5392459950489856 LECGGGPWGNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LECGGGPWGNK 11 0 P00352 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ; 109.44 0.005783399999999999 0.0 62109.0 75389.0 73487.0 87500.0 90250.0 75883.0 55620.0 65144.0 53781.0 49005.0 False True 72622.82699133367 82873.12169145636 75239.20878099951 82597.6586788273 72566.16036504597 71903.56189561318 50351.270946071505 63434.0390257734 54567.44538134407 57889.21857663348 1.2545138590046074 1.4315812810938067 1.2997102160119538 1.4268228300488268 1.253534978520797 1.2420890048883209 0.869786675033741 1.0957833010269384 0.942618448184923 1.0 15.82100706188538 -7.056198324660822 3.0812733959839815 0.9853571065379769 1.340487238366279 0.8159072596052891 0.07974148511533345 0.10245608152591147 1.9257180458214807 0.030638632900138216 0.023928525796083067 8.786211945698646e-08 7.056198324660822 0.355130131828302 LECGGGPWGNK ddPTM_PC-9_Lapatinib_30min_R1 2 LECGGGPWGNK 11 0 P00352 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ; 157.99 0.0017526 94086000.0 106267.0 97453.0 93496.0 86152.0 82650.0 83219.0 72322.0 68793.0 71484.0 76076.0 False True 104751.61309301898 97227.35356599462 85809.11978499687 92487.90547464725 77788.68949615202 79659.91736296391 76066.4792857362 71989.37392119344 63432.71916010859 89225.63523510174 1.17400803947215 1.0896795893894065 0.9617092616813245 1.0365620287370296 0.8718199572486721 0.892791821017211 0.8525182150321227 0.8068238879051715 0.7109248255052365 1.0 16.44517064701757 -5.384125604876888 0.584637815951069 0.8247046754188342 1.2571624692284453 0.6697465117055714 0.0760876854588491 1.1816171191472145 0.4955299828127072 0.04371333686680338 0.31628563337228693 4.129280593512438e-06 5.384125604876888 0.43245779380961114 LEDEDEDLGAPPGEEY(ph)GDGSPSREDSMVPPK ddPTM_PC-9_AZD4547_30min_R2 1 LEDEDEDLGAPPGEEYGDGSPSREDSMVPPK 31 1 A0A494BZV2;H0Y2S9 A0A494BZV2 MPRIP 1 LEDEDEDLGAPPGEEY(0.455)GDGS(0.405)PS(0.075)REDS(0.065)MVPPK 56.533 0.00098288 3966100.0 6379.7 7328.2 7927.9 11337.0 10192.0 8552.0 7303.2 9764.2 7652.7 7435.4 True False 8408.311893996495 9696.89733923841 7822.770866002162 8723.429804903968 8777.016726725935 8017.242088074372 7953.170651826924 8255.367248994566 8057.206098703309 7175.0889091596255 1.171875638121021 1.351467202986081 1.0902681437181516 1.2157939665064987 1.2232624344935028 1.1173718109387696 1.1084421046928086 1.1505595754299116 1.122941638871901 1.0 12.808780993524833 -12.65223616071608 0.03086001410390362 1.1837974467186709e-06 1.9328721514303497 0.48741372268611394 0.06407088610302941 790.5695222649198 2.571018851869373 111.52229217697642 57.239629995875404 2.2272236998939617e-13 12.65223616071608 1.932870967632903 LEDEDEDLGAPPGEEYGDGS(ph)PSREDSMVPPK ddPTM_PC-9_AZD4547_30min_R2 1 LEDEDEDLGAPPGEEYGDGSPSREDSMVPPK 31 1 A0A494BZV2;H0Y2S9 A0A494BZV2 MPRIP 1 LEDEDEDLGAPPGEEY(0.466)GDGS(0.505)PS(0.024)REDS(0.006)MVPPK 49.793 0.016778 5123200.0 13097.0 12336.0 16365.0 19971.0 18049.0 15462.0 13422.0 19935.0 14179.0 17655.0 True False 17261.573565476756 16323.37075637198 16147.98940729896 15366.994498874219 15543.207898418023 14495.158695721011 14616.531998140665 16854.503810727638 14928.472992997788 17036.90382376377 1.0131872401251458 0.9581183837877558 0.9478241806339884 0.9019828167040368 0.9123258579846957 0.8508094455227582 0.8579335863687233 0.9892938285663319 0.8762433096660993 1.0 14.056375552908728 -4.969708125881272 1.2008380998693176 0.9075723757699695 1.0366414606391496 0.292090269180711 0.047513479787665555 1.358084308868216 2.1063632882057726 0.014631609323162046 0.2020769420817615 1.072239677895432e-05 4.969708125881272 0.12906908486918012 LEDEDEDLGAPPGEEYGDGS(ph)PSREDSMVPPK ddPTM_PC-9_Lapatinib_30min_R1 1 LEDEDEDLGAPPGEEYGDGSPSREDSMVPPK 31 1 A0A494BZV2;H0Y2S9 A0A494BZV2 MPRIP 1 LEDEDEDLGAPPGEEY(0.216)GDGS(0.596)PS(0.163)REDS(0.025)MVPPK 47.286 0.024662 2370300.0 6232.5 5896.6 4816.8 5140.2 4685.7 5923.8 4252.0 5427.7 6923.2 5793.3 True False 6143.623407099478 5882.946784986021 4420.781297385699 5518.2274552045355 4410.096338440648 5670.452883052261 4472.147754804218 5679.890756793021 6143.436311472 6794.664185912979 0.9041835238652015 0.8658186223806066 0.6506254284871169 0.8121413073872271 0.6490528770478267 0.834544979398469 0.6581852513147136 0.835933991935737 0.9041559881956881 1.0 12.730186534802653 -8.350793391536431 2.106044861326265 0.9930241197457159 0.7666054449201108 0.4192915905473653 0.08773808179977806 0.28678698803482205 2.483333904168433 0.08217770200628827 0.02334132189176101 4.458683124737889e-09 8.350793391536431 -0.22641867482560507 LEDFFAR ddPTM_PC-9_AZD4547_30min_R2 2 LEDFFAR 7 0 P11413;P11413-2;P11413-3;E7EUI8;E7EM57;E9PD92 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ; 128.86 0.020496 18287100.0 82841.0 72940.0 104110.0 141672.0 125570.0 102927.0 93039.0 118429.0 102382.0 109013.0 False True 109182.71480015707 96516.42858055867 102729.43337573444 109011.70921058068 108136.77299597484 96490.95841899341 101319.29075957464 100128.51927768571 107793.70350300435 105196.48805097486 1.0378931542586347 0.9174871744177419 0.9765481270244976 1.036267571572894 1.0279504097472836 0.9172450545329704 0.9631432820312266 0.9518237835959564 1.0246891840226735 1.0 16.682727015987027 -6.734103092528078 24.99951078483265 0.9678543421334772 0.9954856513368372 0.09093115085268777 0.04249934067980707 597.2216508357202 546168.4744060595 0.014480147076451464 0.014476672124213075 1.8445775026551411e-07 6.734103092528078 0.02763130920335999 LEDFFAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LEDFFAR 7 0 P11413;P11413-2;P11413-3;E7EUI8;E7EM57;E9PD92 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 128.86 0.020496 7052800.0 30882.0 33342.0 44181.0 37923.0 42959.0 30984.0 37039.0 33837.0 25369.0 25574.0 False True 36109.71265269712 36651.973410398496 45234.44259737554 35798.29725802486 34541.492333761824 29359.144495785316 33530.39778086198 32948.814603265026 25739.973631567238 30210.363756327377 1.195275665793139 1.2132251602803679 1.4973153902491976 1.1849674352407333 1.1433656546597297 0.9718236010857771 1.1098971879754094 1.0906460732821894 0.8520246177497998 1.0 14.8827559348927 -6.358170455120281 2.1505748638133726 1.0181163640826967 1.2930504074483815 0.5914482622278322 0.10508233694427324 0.23499621556300726 2.1350990482847467 0.03704160186587004 0.044612790033077596 4.38358613765884e-07 6.358170455120281 0.27493404336568483 LEDFFAR ddPTM_PC-9_Lapatinib_30min_R1 2 LEDFFAR 7 0 P11413;P11413-2;P11413-3;E7EUI8;E7EM57;E9PD92 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ; 132.09 0.019858 22269000.0 86935.0 105733.0 131575.0 114316.0 124052.0 119669.0 109882.0 101134.0 122975.0 101199.0 False True 85695.29095807343 105488.18173471617 120757.41139418744 122723.17998699694 116755.50525561586 114551.03583206396 115571.15230324486 105833.05484781852 109124.26051584071 118691.11231080872 0.7220025938729829 0.8887622643427682 1.0174090464159427 1.033971100259215 0.9836920640685867 0.9651189006645805 0.9737136172471463 0.8916678998734157 0.9193970668173037 1.0 16.856852383256744 -4.845377883301959 2.9410596267436615 0.9711583393050106 0.6977941294609934 0.7795906571333586 0.04065962307918872 0.1707986804601598 2.315315738277154 0.01182158319919668 0.10406539487958981 1.4276512065351525e-05 4.845377883301959 -0.2733642098440172 LEDGS(ph)HLT(ph)GQTLKQTY(ph)SK ddPTM_PC-9_Lapatinib_30min_R1 1 LEDGSHLTGQTLKQTYSK 18 1 A0A0B4J1R0;J3QT06;Q14406-4;Q14406-3;Q14406-2;Q14406 A0A0B4J1R0 CSHL1 Chorionic somatomammotropin hormone-like 1 3 LEDGS(1)HLT(1)GQT(0.194)LKQT(0.111)Y(0.351)S(0.344)K 54.668 0.044876 0.0 1068.0 946.09 683.93 1119.6 1850.0 776.38 2013.0 720.35 988.18 929.86 True False 1052.7701241527873 943.8993867325959 627.6999154461471 1201.9391188761124 1741.1866372399415 743.1760372301751 2117.223290315353 753.820090766965 876.8807624032813 1090.5850620394324 0.9653260078439642 0.8654981803688663 0.5755625464668718 1.1021048799517243 1.5965619719601343 0.6814471086193037 1.9413646528002788 0.6912070566575476 0.804046188532496 1.0 10.090886584486244 -5.894797337229776 8.65259326639271 1.1431506229554482 0.8097352210456784 0.12142801622802302 0.3844353780758122 0.5294192275619769 39.62502401123474 0.10686101074982769 0.15890336892622817 1.2740974977118464e-06 5.894797337229776 -0.3334154019097698 LEDLDTCMMT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 8 LEDLDTCMMTPK 12 0 Q5VZK9-2;Q5VZK9 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 LEDLDT(0.002)CMMT(0.998)PK;LEDLDT(0.018)CMMT(0.982)PK;LEDLDT(0.003)CMMT(0.997)PK;LEDLDT(0.003)CMMT(0.997)PK;LEDLDT(0.061)CMMT(0.939)PK;LEDLDT(0.001)CMMT(0.999)PK;LEDLDTCMMT(1)PK;LEDLDTCMMT(1)PK 101.53 0.0015853 174443100.0 363103.0 392442.0 383500.0 355764.0 397924.0 480754.0 505024.0 479394.0 483651.0 467115.0 True False 478562.20098841767 519291.2018784147 378414.53942555183 273748.10629900795 342679.12126821873 450692.37638097705 549970.1576388754 405314.67267820134 509215.8044669146 450761.4460287412 1.0616750948968778 1.1520310941706047 0.8395006777075242 0.6073015088374558 0.7602227836636433 0.9998467711727064 1.220091386439932 0.8991777718548669 1.1296791439311478 1.0 18.78200460041333 -6.9875659022970575 22.705765684784474 1.061854344761533 0.8810546842050317 0.21781177664532858 0.1603897204525555 131.65927035833076 240417.7798741163 0.06310357715544195 0.05559500636677558 1.0290443623437112e-07 6.9875659022970575 -0.1807996605565012 LEDLDTCMMT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LEDLDTCMMTPK 12 0 Q5VZK9-2;Q5VZK9 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 LEDLDT(0.015)CMMT(0.985)PK;LEDLDT(0.001)CMMT(0.999)PK;LEDLDTCMMT(1)PK;LEDLDT(0.001)CMMT(0.999)PK;LEDLDT(0.002)CMMT(0.998)PK 92.19 0.005324100000000001 90856700.0 210151.0 240294.0 213494.0 240483.0 244358.0 170658.0 246504.0 159388.0 163989.0 172242.0 True False 245725.4136285526 264148.80027227785 218584.50664050394 227009.51716640507 196477.80403858045 161708.3940537609 223153.35658558793 155204.23388554546 166387.02888829226 203468.11113307826 1.207685136801786 1.298231938170947 1.0742936837779893 1.1157007154695093 0.9656442129650193 0.7947603835964032 1.0967485535835861 0.7627938993547454 0.8177548214396451 1.0 17.634443177944775 -5.930062476095415 0.9828172746943785 0.8826040892545133 1.2630810536394312 0.6347182412397978 0.10316069876062116 0.3769178167068164 0.7258415743018319 0.0425994346386632 0.10141229664920566 1.1747285504153972e-06 5.930062476095415 0.38047696438491796 LEDLDTCMMT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 8 LEDLDTCMMTPK 12 0 Q5VZK9-2;Q5VZK9 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 LEDLDT(0.003)CMMT(0.997)PK;LEDLDT(0.007)CMMT(0.993)PK;LEDLDT(0.091)CMMT(0.909)PK;LEDLDT(0.004)CMMT(0.996)PK;LEDLDT(0.007)CMMT(0.993)PK;LEDLDT(0.001)CMMT(0.999)PK;LEDLDT(0.006)CMMT(0.994)PK;LEDLDTCMMT(1)PK 106.54 0.0063363 66072400.0 350451.0 438406.0 317160.0 357001.0 384817.0 346639.0 333048.0 325023.0 345807.0 259542.0 True False 345453.5044751574 437390.8978425848 291084.32907300483 383256.0444604253 362182.8206393314 331814.0580249756 350291.59582362045 340124.7551347976 306858.5741508547 304403.48888202285 1.1348539589473767 1.4368787277996793 0.9562450487741285 1.2590395920493644 1.1898116607319897 1.090046829764084 1.1507476379792163 1.1173484127398394 1.0080652336734004 1.0 18.215625368639465 -7.179655217772801 0.26115324892432656 0.9707891603500889 1.2828972272582182 0.26158536252282927 0.11477095421357783 3.409341216179453 0.6553775248085596 0.21744533683442685 0.3807999542960699 6.612181744644241e-08 7.179655217772801 0.3121080669081293 LEDLVCDVVDR ddPTM_PC-9_Lapatinib_30min_R1 2 LEDLVCDVVDR 11 0 O43776 O43776 NARS Asparagine--tRNA ligase, cytoplasmic 0 ; 119.53 0.0028136999999999997 833980.0 6851.9 6734.7 7574.299999999999 6787.0 7369.299999999999 6789.5 5796.4 7514.6 8180.0 6511.6 False True 6754.190649515428 6719.10621592873 6951.570291643518 7286.1386207682945 6935.852262601239 6499.128912097523 6096.509229996982 7863.755749396032 7258.682260781277 7637.121383838398 0.8843895900107834 0.8797956557489891 0.9102343595525879 0.9540425318087977 0.9081762504493934 0.8509919622137886 0.7982731874470864 1.029675365123466 0.9504474128356831 1.0 12.898813238650954 -7.77998582282283 24.999830151506742 0.9925460590228236 0.8869596513333918 0.5843154373844438 0.04232651054577301 199.50375029488225 268918.8692426811 0.024798151993359618 0.01194692866662934 1.6596410841370813e-08 7.77998582282283 -0.10558640768943173 LEDNDS(ph)AASDPDAETTAR ddPTM_PC-9_AZD4547_30min_R2 1 LEDNDSAASDPDAETTAR 18 0 Q9BYV8-5;F8WF85;C9J6R3;C9J9X8;C9JCX6;C9JXA0;Q9BYV8-2;Q9BYV8 Q9BYV8-5 CEP41 Centrosomal protein of 41 kDa 1 LEDNDS(0.917)AAS(0.081)DPDAET(0.001)T(0.001)AR 129.89 1.4592e-05 0.0 8467.7 10147.0 11502.0 14649.0 13323.0 12338.0 9134.5 12100.0 8698.6 10541.0 True False 11160.252460898499 13426.819314600061 11349.475964726713 11271.899374793878 11473.331421719942 11566.502909572228 9947.452804128745 10230.223030338822 9158.390237456138 10171.962798430695 1.0971582065381005 1.3199831321317372 1.1157606638590618 1.1081341524895154 1.127936824885952 1.1370964619883075 0.9779285474444925 1.0057275309655198 0.9003562457846456 1.0 13.312310470380856 -7.196908820120486 1.0448577877440985 0.9484386191798034 1.1726411330309252 0.6314613553481107 0.06653253158913167 0.33449111482169513 0.7203709779555859 0.04582580334454877 0.027520525992214204 6.354643332228863e-08 7.196908820120486 0.22420251385112178 LEDNPSSGS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 2 LEDNPSSGSPPR 12 0 Q05D32;H0YMH7;Q05D32-2 Q05D32 CTDSPL2 CTD small phosphatase-like protein 2 1 LEDNPS(0.043)S(0.132)GS(0.825)PPR;LEDNPS(0.012)S(0.041)GS(0.947)PPR 92.15100000000001 0.0060168 7522000.0 29742.0 28462.0 37599.0 32830.0 32377.0 36808.0 30350.0 45772.0 38114.0 36815.0 True False 39199.337327969006 37661.78489525448 37100.412693249826 25261.550718443777 27882.012417700716 34506.389941281755 33051.091204259385 38698.98913592303 40128.62822872685 35526.11805561388 1.1033948957385362 1.0601154011901146 1.0443137253322046 0.7110698297770228 0.7848313844494127 0.9712963822071468 0.9303321897574062 1.089310942314109 1.1295528592768855 1.0 15.116592433321726 -7.7615403650143655 24.999995077870036 1.0820739610762726 0.9379879950307465 0.19986174126367084 0.11778765961635994 4.526486692183375 1119350.0225712701 0.06674768831469816 0.03528322609178953 1.731648077178701e-08 7.7615403650143655 -0.14408596604552615 LEDNPSSGS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LEDNPSSGSPPR 12 0 Q05D32;H0YMH7;Q05D32-2 Q05D32 CTDSPL2 CTD small phosphatase-like protein 2 1 LEDNPS(0.029)S(0.09)GS(0.88)PPR 83.243 0.011235 6138600.0 24007.0 33444.0 34102.0 28160.0 34104.0 21695.0 25866.0 17411.0 18534.0 19343.0 True False 28070.910940136633 36764.099296304004 34915.12101255521 26582.286495951805 27421.566017612437 20557.276008135235 23415.785226376942 16953.97969847939 18805.024687116846 22849.73278089626 1.2285006222744799 1.6089509513669669 1.5280319182439777 1.1633521823141926 1.2000825690416173 0.8996724909326881 1.0247728256128201 0.7419771540021655 0.8229866347863363 1.0 14.479889673150955 -6.386772734548447 1.1226910060619275 0.8656636109693971 1.4688992786523576 0.7522237795520653 0.13437289953842535 0.22567063335526236 0.5959992990000328 0.059603705383616847 0.07819274891699 4.104188181651849e-07 6.386772734548447 0.6032356676829604 LEDNPSSGS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 2 LEDNPSSGSPPR 12 0 Q05D32;H0YMH7;Q05D32-2 Q05D32 CTDSPL2 CTD small phosphatase-like protein 2 1 LEDNPSS(0.002)GS(0.998)PPR;LEDNPS(0.009)S(0.035)GS(0.956)PPR 114.21 0.00077932 10455400.0 27727.0 44047.0 42794.0 46673.0 53105.0 40253.0 36936.0 39130.0 41760.0 39707.0 True False 27331.60789549095 43945.01187773964 39275.64250961707 50105.4881165638 49981.46830844706 38531.47302432601 38848.36535076397 40948.122651088095 37056.54904770491 46570.30204374827 0.5868892125676051 0.9436273751554709 0.8433624173775258 1.0759107396274683 1.0732476731951262 0.8273829314684161 0.8341875325238326 0.8792754363633141 0.7957120186356937 1.0 15.507122618710152 -4.7586539501615315 24.968255182896094 0.9172339238791342 0.5868887623426449 0.5146231791094036 0.09679917331209979 67.33563326387812 603472.3077267745 0.02576511689299533 0.17365419284989891 1.7431953142198204e-05 4.7586539501615315 -0.3303451615364893 LEDTENWLYEDGEDQPK ddPTM_PC-9_AZD4547_30min_R2 1 LEDTENWLYEDGEDQPK 17 0 A0A087WYC1;P34932 A0A087WYC1 HSPA4 Heat shock 70 kDa protein 4 0 159.0 3.7982e-17 0.0 3393.4 4326.8 4983.5 7463.1 4919.2 5965.5 6527.0 6534.0 5839.3 5224.2 False True 4472.430612895232 5725.353484814387 4917.415533838942 5742.597598745592 4236.253991572825 5592.476341955995 7107.890355525567 5524.320436382961 6147.953476832782 5041.3023481227265 0.8871577826631782 1.1356893694238328 0.9754256329557545 1.139109936717843 0.8403094476470581 1.1093316678454157 1.4099313758026026 1.0958121641801746 1.2195169129505095 1.0 12.299580766098584 -6.997711541161908 24.98926800010287 1.1993469040428746 1.0066471148566762 0.3050798485557298 0.13127462935685577 82.62302421094239 902205.425788283 0.04383016608320866 0.03842029520718976 1.0052832787602679e-07 6.997711541161908 -0.19269978918619834 LEDTENWLYEDGEDQPK ddPTM_PC-9_Lapatinib_30min_R1 2 LEDTENWLYEDGEDQPK 17 0 A0A087WYC1;P34932 A0A087WYC1 HSPA4 Heat shock 70 kDa protein 4 0 ; 172.1 2.4275e-24 3447200.0 45707.0 36008.0 42692.0 39595.0 40414.0 39085.0 35601.0 34439.0 36205.0 36570.0 False True 45055.209798362775 35924.625688324915 39182.02855588572 42506.948385047945 38036.927976981075 37413.42566158506 37444.24558296915 36039.16166575066 32127.21164444818 42891.075773537996 1.0504565107261767 0.8375780984838088 0.9135240338284869 0.9910441185826576 0.8868261588451057 0.8722892813210245 0.873007843885107 0.8402484902928297 0.7490418709495118 1.0 15.388389880966724 -6.495573840615869 4.849613962413243 0.8589216767730211 0.9383660362681734 0.19363699571376813 0.07673084931725978 0.3345210058026673 20.300715114014448 0.024225443917913043 0.02634193238062187 3.19467114689959e-07 6.495573840615869 0.07944435949515227 LEDVKNS(ph)PTFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LEDVKNSPTFK 11 1 H0YC42;P55327-2;P55327;P55327-3 H0YC42 TPD52 Tumor protein D52 1 LEDVKNS(0.977)PT(0.023)FK 53.869 0.04335 10722000.0 97589.0 93207.0 69032.0 87173.0 98222.0 95178.0 137270.0 108790.0 114470.0 86475.0 True False 114108.89022939118 102459.97497639632 70677.98468531782 82288.97942867916 78976.10419252659 90186.69812870688 124266.79185126313 105934.37777253287 116143.9071940361 102152.23296427651 1.1170474390833534 1.0030125823311902 0.6918887882757736 0.8055524293576265 0.7731216626477974 0.8828656556166121 1.2164862993716472 1.037024592595827 1.1369688534821611 1.0 16.64036121498645 -7.189591571994559 8.164173409185079 1.1004166930593646 0.8672669193305006 0.42643247116887684 0.12383223877886711 0.33150432535650276 34.735374033903135 0.05059055877854557 0.03912756112706209 6.462617138575696e-08 7.189591571994559 -0.23314977372886403 LEDVKNS(ph)PTFK ddPTM_PC-9_Lapatinib_30min_R1 1 LEDVKNSPTFK 11 1 H0YC42;P55327-2;P55327;P55327-3 H0YC42 TPD52 Tumor protein D52 1 LEDVKNS(0.982)PT(0.018)FK 72.681 0.012563 11027000.0 48599.0 44650.0 46051.0 61169.0 55481.0 73706.0 92660.0 101040.0 74395.0 56905.0 True False 47905.9693480349 44546.615668287835 42264.86454200067 65667.5723138022 52217.71665984283 70553.76619707793 97457.48141113805 105734.68726465457 66015.85168591978 66740.95342885358 0.7177897061225395 0.6674554884172416 0.6332673174508269 0.9839172043564584 0.7823939272235204 1.057128533117059 1.4602350791261702 1.5842549713852776 0.9891355800946602 1.0 16.026284675857724 -6.919209096562484 2.869358616137851 1.3058764828590588 0.7529561710369368 0.5941859016284334 0.19399126767151564 0.1729169372101099 2.881322596946096 0.07592186190262401 0.06445682406723718 1.2044559002464134e-07 6.919209096562484 -0.552920311822122 LEEEQIILEDQNCK ddPTM_PC-9_Lapatinib_30min_R1 1 LEEEQIILEDQNCK 14 0 P35579 P35579 MYH9 Myosin-9 0 186.13 5.440999999999999e-36 0.0 13953.0 13085.0 17411.0 14289.0 14626.0 11442.0 15062.0 17716.0 11665.0 10254.0 False True 13754.027661333186 13054.702486440003 15979.534788403585 15339.860726706665 13765.727435822364 10952.652332604745 15841.836661067982 18539.150035437695 10351.164862104357 12026.390237403852 1.143653863696866 1.0855046467590872 1.328705827182031 1.2755166283393524 1.1446267054439092 0.9107181886165956 1.317256163183324 1.5415390378551161 0.8607042227775633 1.0 13.55391605713529 -6.3723683557409645 16.750007902679116 1.1546924114835728 1.2084901892016424 0.028157052787416204 0.19604531160384037 14.187015660238755 2098.378768006104 0.06282753051146568 0.07123908636465483 4.242595668757683e-07 6.3723683557409645 0.053797777718069595 LEEFS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 LEEFSPR 7 0 Q9UGU0-2;Q9UGU0;I3L1M7 Q9UGU0-2 TCF20 Transcription factor 20 1 LEEFS(1)PR;LEEFS(1)PR 93.598 0.013808 4639900.0 24365.1 25929.0 33809.0 44063.0 39199.0 31196.0 25771.0 39570.0 30514.0 31311.0 True False 32112.694974436734 34310.04218076919 33360.67056959182 33904.95611656375 33756.895473992336 29245.30918844342 28064.56907495778 33455.365728141085 32126.907744434327 30214.811420326674 1.0628130200022787 1.1355371941089625 1.1041164581668979 1.122130323598663 1.1172300566232483 0.9679130139719809 0.9288348248990778 1.1072505223591886 1.0632834108248417 1.0 14.882968317323968 -6.745879968062934 24.997202200840402 1.014870667321332 1.110403642786102 0.4855572648240395 0.048812262174894795 228.2970157500951 366773.3972315809 0.017332336942174675 0.017275609684987717 1.7952297305950655e-07 6.745879968062934 0.09553297546477002 LEEFS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LEEFSPR 7 0 Q9UGU0-2;Q9UGU0;I3L1M7 Q9UGU0-2 TCF20 Transcription factor 20 1 LEEFS(1)PR 78.516 0.028217000000000002 2747100.0 15986.0 14237.0 18757.0 19587.0 19451.0 15682.0 18593.0 12854.0 12356.0 11085.0 True False 18692.114062107892 15650.355270944865 19204.23801631863 18489.6038919108 15639.716180171816 14859.608313416777 16831.73643833707 12516.596119938777 12536.683124744564 13094.622751188273 1.4274648775514875 1.1951741999993601 1.466574362715103 1.4119997378491074 1.1943617221620675 1.1347870492923013 1.2853930012462307 0.9558577102805773 0.9573916990931962 1.0 13.676686876593466 -7.290865907932937 0.7791646827667233 0.9516605409894682 1.365620210316292 0.6888590511666999 0.10250871674228165 0.3910572907258572 0.4626950054771457 0.08702301380639713 0.05236630615289452 5.118398459947223e-08 7.290865907932937 0.4139596693268238 LEEFS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 LEEFSPR 7 0 Q9UGU0-2;Q9UGU0;I3L1M7 Q9UGU0-2 TCF20 Transcription factor 20 1 LEEFS(1)PR;LEEFS(1)PR 93.178 0.014088999999999999 3538800.0 42915.0 36126.0 41162.0 28354.0 31781.0 38261.0 34353.0 34316.0 38925.0 32035.0 True False 42303.024230352865 36042.35246657481 37777.81924991492 30439.247746171226 29911.704063850037 36624.66622074725 36131.63024948007 35910.4466367171 34540.85660157838 37572.20706604566 1.125912676782368 0.9592822802029803 1.0054724542401203 0.81015330541174 0.7961125097407842 0.9747808042356204 0.9616584457220387 0.9557715513914989 0.9193193399807823 1.0 15.197378244789615 -4.467287443119548 1.443727347559074 0.9192323248205418 1.3708404291182745 0.42963697816883617 0.06820659600667368 2.6573372188010285 2.829914709590395 0.02076845329331402 2.155083071225849 3.4096716363171155e-05 4.467287443119548 0.4516081042977327 LEEGVAS(ph)DEEAEEAQPGSGPSPEPEGSPPAHPQ ddPTM_PC-9_AZD4547_30min_R2 1 LEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 33 0 Q7Z406;Q7Z406-6;Q7Z406-2;Q7Z406-4;A1L2Z2 Q7Z406 MYH14 Myosin-14 1 LEEGVAS(1)DEEAEEAQPGSGPSPEPEGSPPAHPQ 119.09 5.7895e-24 8215300.0 18968.0 17823.0 23383.0 34039.0 32808.0 23120.0 20208.0 30238.0 18981.0 28999.0 True False 24999.429441090586 23583.9362022388 23072.926141819218 26191.834447307592 28253.175507302265 21674.302745121568 22006.47285191677 25565.411900114483 19984.2969095205 27983.753836608637 0.8933551083624125 0.8427724293152569 0.8245114746412248 0.9359657249787254 1.0096277887615337 0.7745316397390195 0.7864017451128259 0.9135805027940728 0.7141392475864634 1.0 14.77230188308882 LEEGVAS(ph)DEEAEEAQPGSGPSPEPEGSPPAHPQ ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 33 0 Q7Z406;Q7Z406-6;Q7Z406-2;Q7Z406-4;A1L2Z2 Q7Z406 MYH14 Myosin-14 1 LEEGVAS(1)DEEAEEAQPGSGPSPEPEGSPPAHPQ 97.389 7.0374e-16 7992000.0 17342.0 17237.0 21568.0 23933.0 26827.0 18260.0 16115.0 15761.0 16847.0 16516.0 True False 20277.658079887096 18948.17544463558 22082.262917095497 22592.111601832894 21570.441929230856 17302.413455107137 14588.470537503455 15347.290450159884 17093.35550360729 19510.22005941593 1.039335180132978 0.971192297520545 1.1318305406011175 1.1579629308655386 1.1055970595688198 0.8868384570965784 0.7477348022255053 0.786628259620939 0.876123152458128 1.0 14.251942430014974 -6.843788807791371 4.626209962761382 0.833231750301816 1.082175517794328 0.6598865835371319 0.07918739810145296 0.12522261498839907 4.847022473252594 0.02936443242557273 0.02608798516813774 1.4328845244741202e-07 6.843788807791371 0.248943767492512 LEEGVAS(ph)DEEAEEAQPGSGPSPEPEGSPPAHPQ ddPTM_PC-9_Lapatinib_30min_R1 1 LEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 33 0 Q7Z406;Q7Z406-6;Q7Z406-2;Q7Z406-4;A1L2Z2 Q7Z406 MYH14 Myosin-14 1 LEEGVAS(1)DEEAEEAQPGSGPSPEPEGSPPAHPQ 124.42 4.4827e-23 7025000.0 23017.0 18107.0 22052.0 19480.0 19618.0 23968.0 13908.0 19105.0 26702.0 14355.0 True False 22688.773359199167 18065.074353990774 20238.96968318166 20912.624183375035 18464.107810471975 22942.94451213688 14628.088187633355 19992.688046231502 23694.539575474537 16836.242623164842 1.3476150152399133 1.0729872904738966 1.202107271567531 1.2421194355206984 1.0966881520861054 1.3627116825086543 0.8688451761503302 1.187479207428606 1.4073531788424944 1.0 14.039282584832538 LEEPPELNRQS(ph)PNPR ddPTM_PC-9_AZD4547_30min_R2 1 LEEPPELNRQSPNPR 15 1 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 LEEPPELNRQS(1)PNPR 76.868 0.006372600000000001 19256000.0 32307.0 25725.0 38528.0 51923.0 48694.0 41124.0 38917.0 58007.0 37941.0 39615.0 True False 42579.95397265466 34040.10317020662 38017.093546252 39952.95455235321 41933.6786196225 38552.50977899563 42380.53760778129 49043.35101825323 39946.48380191333 38228.09090786756 1.1138394034710077 0.8904473742161414 0.9944805676505248 1.045120318685092 1.0969336324088397 1.008486400011707 1.1086229158008811 1.2829139476635447 1.0449510517851184 1.0 15.222345534037377 -6.52007729100008 1.0280745016871327 1.1216991122209585 0.9929891602808131 0.1440848311296027 0.09066528944783343 0.7744022008868486 1.756612195037047 0.04544280653131216 0.052982856176378074 3.019414310121014e-07 6.52007729100008 -0.12870995194014545 LEEPPELNRQS(ph)PNPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LEEPPELNRQSPNPR 15 1 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 LEEPPELNRQS(1)PNPR 83.087 0.0033646 90828000.0 74940.0 65536.0 89391.0 100250.0 113660.0 89433.0 89342.0 92650.0 72491.0 72252.0 True False 87625.86186753199 72041.98096766463 91522.42045725549 94633.31751488529 91389.13891513675 84742.9760422013 80878.87897993402 90218.0356707894 73551.04373550182 85350.71565348288 1.0266564398040436 0.844070028189914 1.0723099362028696 1.108758336591916 1.0707483612225277 0.9928795018691003 0.9476063365220724 1.0570272900471913 0.8617507559528055 1.0 16.38111562964373 -8.250377792573495 24.94772555937252 0.9308753692842472 1.0132180388955179 0.15646934770070076 0.0780483271112787 1240.8345259220646 2798530.1200671094 0.055960970563292245 0.020691640968349228 5.618523574330091e-09 8.250377792573495 0.08234266961127068 LEEPPELNRQS(ph)PNPR ddPTM_PC-9_Lapatinib_30min_R1 3 LEEPPELNRQSPNPR 15 1 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 LEEPPELNRQS(1)PNPR;LEEPPELNRQS(1)PNPR;LEEPPELNRQS(1)PNPR 78.529 0.0055692 437888000.0 111046.0 103715.0 123497.0 107453.0 113416.0 103498.0 95155.0 92742.0 101227.0 89810.0 True False 109462.46367665785 103474.85428973069 113343.55337220606 115355.45207269985 106745.09386443537 99071.63180562195 100081.66030300914 97051.13189131631 89825.7492924335 105333.53883569723 1.0391985770781047 0.982354295065831 1.0760442934420265 1.095144560296556 1.0134008127358176 0.9405516315193511 0.9501404909515083 0.9213697077309813 0.8527744371386468 1.0 16.684605346772642 -6.712474804928862 3.069567548178037 0.9269211567424369 1.0464337989570143 0.6139933210251336 0.043524418898218425 0.17419656056701302 3.3499145142521267 0.016149184240628937 0.015459813156305567 1.9387651078116606e-07 6.712474804928862 0.11951264221457736 LEEPTPAPS(ph)TSYSPQADSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LEEPTPAPSTSYSPQADSLR 20 0 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 1 LEEPTPAPS(0.369)T(0.369)S(0.201)Y(0.001)S(0.06)PQADSLR 127.37 2.256e-05 5428400.0 12119.0 11053.0 14976.0 11925.0 19958.0 14522.0 15110.0 16050.0 17405.0 9708.2 True False 14170.507338839336 12150.268793267795 15333.08463679628 11256.880911371632 16047.373169701763 13760.440755480067 13678.671413073373 15628.704506380689 17659.51519797501 11468.219809931092 1.2356326939747138 1.0594729604629718 1.3370065180925768 0.9815717781781226 1.3992906864067323 1.1998759165362343 1.1927458349924636 1.3627838291734484 1.539865427298705 1.0 13.485353841460476 -6.282312754599487 24.946785839338382 1.2919545214408261 1.1598236252863516 0.13087663771914182 0.16141274354784682 1615.5103460177384 1930769.076209106 0.04852934353339361 0.05508425194080413 5.220201239037364e-07 6.282312754599487 -0.1321308961544745 LEEPTPAPSTS(ph)YSPQADSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LEEPTPAPSTSYSPQADSLR 20 0 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 1 LEEPTPAPS(0.03)T(0.03)S(0.62)Y(0.005)S(0.315)PQADSLR;LEEPT(0.005)PAPS(0.317)T(0.165)S(0.409)YS(0.104)PQADSLR 151.63 6.695199999999999e-05 14032000.0 23191.0 31356.0 37697.0 35529.0 39409.0 37893.0 35556.0 33824.0 29237.0 25056.0 True False 27116.778256871257 34468.81645541526 38595.83944666864 33538.42531657216 31687.089349873597 35905.82437318595 32187.87827685219 32936.155839490355 29664.535814030187 29598.45445681314 0.9161552099430437 1.1645478484597371 1.3039815813012638 1.133114074098288 1.0705656741674796 1.2130979482586106 1.0874851024338874 1.1127660698482493 1.0022325948577304 1.0 14.853234224129839 -8.174781455554013 1.8702757837552242 0.9925341944049888 1.1376870852173768 0.20887332573303719 0.09505268939456417 0.5392086222962141 3.3792325069780955 0.08872097857998658 0.02694044556837555 6.686803243481501e-09 8.174781455554013 0.14515289081238802 LEEPTPAPSTS(ph)YSPQADSLR ddPTM_PC-9_Lapatinib_30min_R1 1 LEEPTPAPSTSYSPQADSLR 20 0 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 1 LEEPT(0.002)PAPS(0.131)T(0.131)S(0.643)YS(0.093)PQADSLR 146.67 1.8594e-14 0.0 16557.0 16114.0 18508.0 17162.0 20701.0 15427.0 14537.0 11558.0 18990.0 13119.0 True False 16320.894143818065 16076.689023041201 16986.343682946048 18424.150730753714 19483.407879731898 14767.223172093449 15289.65472991271 12095.026874553454 16851.146226434772 15386.601670031307 1.0607211711736513 1.0448498874416166 1.1039698074481632 1.1974152009562113 1.2662580274421478 0.9597455948220048 0.9936992623714033 0.7860752578076485 1.0951831072130749 1.0 13.909387008540357 -6.846259866240958 11.242361950259834 0.9548287536124077 1.1313729161595552 0.44271857578941276 0.0935557010042593 0.4398085125094408 55.61441605659086 0.03386483091953886 0.02987145247573213 1.4247548163121272e-07 6.846259866240958 0.17654416254714744 LEEPTPAPSTSYS(ph)PQADSLR ddPTM_PC-9_AZD4547_30min_R2 2 LEEPTPAPSTSYSPQADSLR 20 0 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 1 LEEPTPAPS(0.001)T(0.001)S(0.003)YS(0.994)PQADSLR;LEEPTPAPS(0.109)T(0.109)S(0.244)Y(0.079)S(0.46)PQADSLR 309.09 4.143399999999999e-139 179284000.0 62003.0 61171.0 100329.0 114109.0 98144.0 90527.0 67833.0 100602.0 69744.0 83605.0 True False 81718.66425748303 80943.32948589734 98998.57190619607 87802.93301647589 84518.39968875493 84866.33237922222 73870.00559006662 85056.27250397891 73430.52545480194 80678.0143973814 1.0128988035696551 1.0032885674058503 1.2270824046136826 1.0883130140511459 1.0476013858305637 1.0519139943282587 0.9156150673988854 1.054268292784603 0.9101677328487314 1.0 16.299887957125733 -7.069651300343218 4.930505901639042 0.9744580025272884 1.078551701056159 0.34483839766794766 0.06913705653790946 0.27118173784698285 12.524848881214707 0.027475646449423807 0.021444163305086007 8.518217004053384e-08 7.069651300343218 0.10409369852887052 LEEPTPAPSTSYS(ph)PQADSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LEEPTPAPSTSYSPQADSLR 20 0 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 1 LEEPTPAPS(0.012)T(0.012)S(0.029)Y(0.07)S(0.877)PQADSLR;LEEPTPAPS(0.001)T(0.002)S(0.005)YS(0.993)PQADSLR;LEEPTPAPS(0.195)T(0.195)S(0.132)YS(0.478)PQADSLR 272.06 2.6644999999999992e-80 133963400.0 114799.0 110493.0 153165.0 113810.0 149249.0 122401.0 120562.0 112345.0 121714.0 98802.0 True False 134232.20331639724 121462.0148172026 156817.03448149704 107433.59467699818 120004.72984291095 115982.07608535433 109141.49456670744 109396.06278936703 123493.8369897344 116714.02048379809 1.1500949308402153 1.040680582450363 1.3436006559577471 0.9204857671055193 1.0281946363039536 0.9937287363128292 0.9351189695488055 0.9373000975881307 1.0580891351170398 1.0 16.832618352255665 -5.788361325194755 24.999903381241268 0.9797122461338181 1.16438114852863 0.5564106575574577 0.08001396467687204 156.26190328518527 145105.29544809248 0.021771699788598584 0.03230233598109806 1.6279410513943873e-06 5.788361325194755 0.18466890239481182 LEEPTPAPSTSYS(ph)PQADSLR ddPTM_PC-9_Lapatinib_30min_R1 2 LEEPTPAPSTSYSPQADSLR 20 0 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 1 LEEPTPAPS(0.002)T(0.008)S(0.204)YS(0.785)PQADSLR;LEEPTPAPS(0.012)T(0.012)S(0.222)YS(0.754)PQADSLR 310.75 1.8795999999999996e-139 153329000.0 98194.0 96189.0 105707.0 86015.0 100927.0 89303.0 74176.0 77976.0 102974.0 58588.0 True False 96793.73555342562 95966.28028033442 97016.17850082017 92340.83003762872 94990.6722901165 85483.71886546061 78016.47033404447 81599.0496253834 91375.98375570805 68714.85773639711 1.4086289158124181 1.3965870474254463 1.411866104314618 1.3438262564970331 1.3823891283384195 1.2440354485399934 1.1353653766312093 1.1875022711741967 1.3297849514037152 1.0 16.0683344562502 -6.859428434653032 3.003669916792595 1.1788316314261735 1.3901093240751803 0.6540647421064456 0.07748828502406638 0.16859105014138626 3.0568279566172305 0.028422218422242327 0.02500434779194514 1.382202153734121e-07 6.859428434653032 0.21127769264900675 LEEPTPAPSTSYSPQADS(ph)LRTPSTEAAHIMLR ddPTM_PC-9_AZD4547_30min_R2 1 LEEPTPAPSTSYSPQADSLRTPSTEAAHIMLR 32 1 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 1 LEEPTPAPS(0.001)T(0.001)S(0.001)Y(0.001)S(0.01)PQADS(0.46)LRT(0.46)PS(0.033)T(0.033)EAAHIMLR 60.95 0.0002748 7207700.0 6522.8 3779.8 14746.0 27640.0 17937.0 14694.0 15103.0 23794.0 16847.0 16289.0 True False 8596.914717331589 5001.54643198239 14550.458405134756 21268.025033743095 15446.757165157283 13775.181857128735 16447.137741612176 20117.184031725777 17737.49802616783 15718.72706798573 0.5469218137161305 0.3181902968573721 0.9256766366768729 1.3530373637608097 0.9826977145380705 0.8763547962598444 1.0463403092677903 1.2798227200406302 1.1284309441502882 1.0 13.940196769724718 -5.385341855800643 4.4399731892453325 1.0938756554928595 0.4373118908115661 0.7677606564451025 0.14323417682040748 0.10089496888785852 3.1481028402227214 0.039755950923050475 0.08723045400729879 4.117732633179655e-06 5.385341855800643 -0.6565637646812934 LEEPTPAPSTSYSPQADS(ph)LRTPSTEAAHIMLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LEEPTPAPSTSYSPQADSLRTPSTEAAHIMLR 32 1 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 1 LEEPTPAPS(0.005)T(0.005)S(0.005)Y(0.005)S(0.033)PQADS(0.237)LRT(0.237)PS(0.237)T(0.237)EAAHIMLR 52.122 0.0024654 6932500.0 11522.0 12538.0 15665.0 19596.0 31157.0 33243.0 25557.0 38773.0 30844.0 28981.0 True False 13472.447030126805 13782.68977924469 16038.51300984332 18498.09965108919 25052.009512395918 31499.678559043106 23136.055943343228 37755.249833389295 31295.03514888486 34235.025886530224 0.3935281683378993 0.4025903127670043 0.46848257287731965 0.5403267318213791 0.7317654613561322 0.920100912540471 0.6758007433680987 1.1028252164472323 0.9141233090522621 1.0 15.063185482861773 -6.360879949093057 0.6693713786901806 0.9902598692070879 0.33807226286215475 0.8488912948879249 0.09580312038571409 0.2909085131792354 0.2839840770741961 0.06261000764780407 0.10325949799047993 4.356322777537183e-07 6.360879949093057 -0.6521876063449331 down LEEPTPAPSTSYSPQADSLRTPS(ph)TEAAHIMLR ddPTM_PC-9_AZD4547_30min_R2 1 LEEPTPAPSTSYSPQADSLRTPSTEAAHIMLR 32 1 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 1 LEEPTPAPS(0.003)T(0.003)S(0.003)Y(0.003)S(0.013)PQADS(0.224)LRT(0.224)PS(0.263)T(0.263)EAAHIMLR 49.445 0.0046681000000000005 7355600.0 2349.2 3156.3 11359.0 27351.0 18665.0 16513.0 15246.0 22712.0 12952.0 21275.0 True False 3096.196733604488 4176.512250189433 11208.372238161252 21045.64951873762 16073.686931352004 15480.439499575787 16602.86446458446 19202.38226983927 13636.616277967945 20530.168725606007 0.15081204519000344 0.20343292381130448 0.545946425865548 1.025108453808696 0.7829300940573514 0.7540337201548662 0.8087056997187139 0.9353251074789916 0.6642232930584656 1.0 14.325457863722452 -5.434319016827618 2.977490117681694 0.8407958050437281 0.17055291889148688 0.8574516774173095 0.10969988957280835 0.08594551683961027 1.456204238361173 0.029187302964017576 0.06909643641813767 3.678586588688975e-06 5.434319016827618 -0.6702428861522411 down LEEQRPER ddPTM_PC-9_Lapatinib_30min_R1 1 LEEQRPER 8 1 Q5W0H4;A0A0B4J2C3;P13693;J3KPG2;E9PJF7;P13693-2;Q9HAU6 Q5W0H4 TPT1;TPT1P8 Translationally-controlled tumor protein;Putative translationally-controlled tumor protein-like protein TPT1P8 0 90.601 0.012124 48770000.0 175690.0 227950.0 216530.0 226180.0 232870.0 252790.0 223540.0 190650.0 239360.0 195320.0 False True 173184.6283823999 227422.19578020598 198727.73922997108 242814.03171436203 219173.04444003542 241978.76098227184 235113.80741037958 199508.29500204342 212400.75622745778 229080.80175245972 0.7559980018296769 0.992759733859994 0.8675006273319771 1.0599492836450877 0.9567499448376716 1.0563030997409788 1.0263357104208104 0.8709079655554385 0.9271870650119949 1.0 17.80549703226282 -4.241397944121381 1.9179273074356016 0.9745549935219041 1.59582784005937e-14 0.4804894413991756 0.06636982195564138 5.546761742695386 4.921941711480287 0.01810835465700823 16.246492224535253 5.7359064011941944e-05 4.241397944121381 -0.9745549935218881 LEESPFVPYDFMNSSTSPAS(ph)PPGSIGDGWPR ddPTM_PC-9_AZD4547_30min_R2 1 LEESPFVPYDFMNSSTSPASPPGSIGDGWPR 31 0 Q8NDV7-2;Q8NDV7-6;Q8NDV7-5;Q8NDV7;H7C269;Q8NDV7-3 Q8NDV7-2 TNRC6A Trinucleotide repeat-containing gene 6A protein 1 LEESPFVPYDFMNS(0.002)S(0.002)T(0.009)S(0.02)PAS(0.959)PPGS(0.007)IGDGWPR 87.37200000000001 1.1065e-07 0.0 7617.8 6929.8 10735.0 15137.0 12558.0 11618.0 7796.3 11651.0 10843.0 10125.0 True False 10040.101939916683 9169.722330375043 10592.6468858756 11647.398514318715 10814.538466858738 10891.52462339197 8490.155596565644 9850.60566334525 11416.13884357677 9770.526831810144 1.0275906420141927 0.9385084845702437 1.0841428582324608 1.1920952385492656 1.1068531567458142 1.1147325841153382 0.8689557628483283 1.008195958407728 1.1684261289175284 1.0 13.254220639808477 -10.119664851584524 15.065546504114456 0.9999873176525862 1.0541760731374081 0.03052192299719636 0.09482681922844068 0.0 0.0 0.09803930778973423 0.023778024792912626 7.591632011563782e-11 10.119664851584524 0.05418875548482194 LEESVALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LEESVALR 8 0 Q08209-3;Q08209;Q08209-2;E9PK68;Q08209-4;E9PPC8 Q08209-3 PPP3CA Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform;Serine/threonine-protein phosphatase 0 94.006 0.031633999999999995 2448800.0 17553.0 20958.0 21413.0 22094.0 24637.0 23726.0 19554.0 20004.0 18333.0 17058.0 False True 20524.37621244714 23038.571733403263 21923.56712925472 20856.144809714457 19809.556708184322 22481.76679276407 17701.703561299582 19478.916195989998 18601.0854423715 20150.48036894629 1.0185551826385766 1.1433261794050222 1.0879922824589787 1.035019732921884 0.9830811149650128 1.1156938386149098 0.8784755121063768 0.9666725477179575 0.9231087845944086 1.0 14.298526611237481 -7.25898441505855 24.999881624674074 0.9392869230292945 1.0636556504629033 0.565311128168948 0.05233524604552021 165.62913301687996 1686678.324400936 0.020777660117426624 0.015310183696808716 5.5082746285440266e-08 7.25898441505855 0.12436872743360883 LEESVALR ddPTM_PC-9_Lapatinib_30min_R1 1 LEESVALR 8 0 Q08209-3;Q08209;Q08209-2;E9PK68;Q08209-4;E9PPC8 Q08209-3 PPP3CA Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform;Serine/threonine-protein phosphatase 0 97.473 0.026733999999999997 1802700.0 16257.0 17418.0 21067.0 16707.0 19707.0 16645.0 19526.0 13570.0 18734.0 14335.0 False True 16025.172198831331 17377.66969115872 19334.95258097171 17935.688512918197 18547.873005452715 15933.13215139012 20536.96073854825 14200.511739720563 16623.979642234288 16812.78564981316 0.9531538992177313 1.0335984799373112 1.1500148151348482 1.0667886266139077 1.103200468487436 0.9476794912666472 1.2215085094346918 0.8446257530130573 0.9887700936946776 1.0 14.03727115886588 -7.779677342433302 24.99999534482596 0.937523506589928 1.0665044587863863 0.29675457092938673 0.08692355609783882 297.79546378485077 408202.3769729269 0.04516972303385638 0.021765705710649175 1.6608203498613658e-08 7.779677342433302 0.12898095219645833 LEETDRR ddPTM_PC-9_AZD4547_30min_R2 2 LEETDRR 7 1 A0A1B0GVU9;A0A0U1RQL2;C9J165;A0A0U1RQT0;P47897-2;P47897;A0A0U1RRJ7;A0A0U1RQJ6;A0A0U1RR66;B4DDN1 A0A1B0GVU9 QARS Glutamine--tRNA ligase 0 ; 133.47 0.0026899999999999997 13046200.0 30827.0 26778.0 35271.0 47706.0 46346.0 38906.0 33673.0 36706.0 37837.0 36502.0 False True 40629.344758567 35433.464827669304 34803.283494337986 36708.11875035269 39911.65789019234 36473.20166962369 36669.831766755386 31033.93111996833 39836.98657423355 35224.076090344104 1.1534538096715226 1.0059444777710607 0.9880538358216451 1.0421314857542965 1.1330789142013362 1.0354622666631703 1.0410445308119125 0.8810431546982602 1.130959019962882 1.0 15.104274245421209 -7.543302581894144 24.999463043759413 0.9958094364222617 1.0550037794897202 0.09693300107774871 0.07394530545644819 537.1172445336596 657441.3465038843 0.033739180127292 0.019482053526377347 2.8621831332332506e-08 7.543302581894144 0.05919434306745852 LEETDRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LEETDRR 7 1 A0A1B0GVU9;A0A0U1RQL2;C9J165;A0A0U1RQT0;P47897-2;P47897;A0A0U1RRJ7;A0A0U1RQJ6;A0A0U1RR66;B4DDN1 A0A1B0GVU9 QARS Glutamine--tRNA ligase 0 76.847 0.0194 3227700.0 10543.0 11673.0 14322.0 13582.0 12000.0 14298.0 10254.0 12662.0 11736.0 10347.0 False True 12327.721666258198 12831.818295830539 14663.490796487467 12821.044573438114 9648.686142720773 13548.187709809523 9282.666887468855 12329.63591649796 11907.616797669327 12222.829193193069 1.008581685255288 1.0498239068068314 1.1996805784256244 1.048942464202821 0.7893987545939164 1.1084330391653145 0.7594532117521858 1.0087382979518664 0.9742111756172389 1.0 13.577290641020808 -6.017699969875553 24.759375313555356 0.9379849544637344 1.0893921285031265 0.2877845235562162 0.106502462978544 778.346816186512 1088781.407500236 0.029761433746375857 0.03929013054180726 9.600636575392996e-07 6.017699969875553 0.15140717403939208 LEETDRR ddPTM_PC-9_Lapatinib_30min_R1 2 LEETDRR 7 1 A0A1B0GVU9;A0A0U1RQL2;C9J165;A0A0U1RQT0;P47897-2;P47897;A0A0U1RRJ7;A0A0U1RQJ6;A0A0U1RR66;B4DDN1 A0A1B0GVU9 QARS Glutamine--tRNA ligase 0 ; 78.616 0.017763 7196700.0 22740.8 23828.0 26345.1 20365.7 20656.1 21811.9 21806.3 21216.2 24941.5 19153.5 False True 22416.512021848037 23772.82772998796 24179.10757302689 21863.461515983625 19441.148809455106 20879.055883022324 22935.323514954634 22201.98210554602 22132.325624361394 22464.156954565497 0.9978790687398675 1.0582559487128447 1.076341641572837 0.9732598272084371 0.8654297087033124 0.9294386575579447 1.0209741483440526 0.988329192608931 0.9852284093778706 1.0 14.455337300289525 -5.847462742121217 6.743349298175079 0.9615026293563743 1.0452273368583045 0.3889939762889282 0.044715341548882716 0.22556635334219266 14.564578881873748 0.013857609806952208 0.020761177950536305 1.420814098472428e-06 5.847462742121217 0.08372470750193017 LEFQQQLGEAPSDAS(ph)P ddPTM_PC-9_AZD4547_30min_R2 2 LEFQQQLGEAPSDASP 16 0 Q9BUW7 Q9BUW7 C9orf16 UPF0184 protein C9orf16 1 LEFQQQLGEAPS(0.023)DAS(0.977)P;LEFQQQLGEAPS(0.002)DAS(0.998)P 124.43 3.5364e-05 5344700.0 20193.0 18053.8 30060.0 36027.0 30708.0 22422.4 23776.2 32397.0 26601.0 27722.0 True False 26613.953959507708 23889.337788698806 29661.38475914493 27721.531761601407 26444.72425866367 21020.32378340024 25892.23573939744 27390.788058998885 28007.074552982158 26751.4612179201 0.994859822523628 0.893010575911867 1.1087762465579094 1.0362623385608365 0.9885338241243079 0.7857635742648434 0.9678811758534115 1.0238987633561683 1.0469362523726724 1.0 14.707330076082743 -7.765613583389012 7.514174171347609 1.0268468533853052 0.9667672387094025 0.09005561219849911 0.08098741443717493 0.34424452464265576 123.81435709242638 0.045153665104513234 0.023383498518325583 1.715482991883741e-08 7.765613583389012 -0.060079614675902726 LEFQQQLGEAPSDAS(ph)P ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LEFQQQLGEAPSDASP 16 0 Q9BUW7 Q9BUW7 C9orf16 UPF0184 protein C9orf16 1 LEFQQQLGEAPS(0.004)DAS(0.996)P;LEFQQQLGEAPSDAS(1)P;LEFQQQLGEAPS(0.319)DAS(0.681)P 154.13 5.9234e-11 0.0 12823.400000000001 14994.699999999999 17975.0 17853.6 20604.699999999997 18712.4 18643.2 21209.7 17446.0 16042.0 True False 14994.148346305168 16483.274719480014 18403.59217056711 16853.32067415216 16567.35694707656 17731.088802702463 16877.181130920544 20652.967848534725 17701.114745410632 18950.287611597872 0.7912359249433509 0.8698165989518803 0.9711510742087008 0.8893437935916954 0.8742535884751997 0.9356633084476649 0.8906029014879672 1.0898498361520796 0.93408158800594 1.0 14.209932124129308 -1.5228787489701556 0.1875904149796899 1.0179420404578021 0.1507713264206665 0.45372675351005687 0.057769649231213305 53.284125463357604 0.6175133565460267 0.12414077586586754 13.325149576944254 0.0299999997451164 1.5228787489701556 -0.8671707140371356 LEFQQQLGEAPSDAS(ph)P ddPTM_PC-9_Lapatinib_30min_R1 2 LEFQQQLGEAPSDASP 16 0 Q9BUW7 Q9BUW7 C9orf16 UPF0184 protein C9orf16 1 LEFQQQLGEAPS(0.007)DAS(0.993)P;LEFQQQLGEAPSDAS(1)P 167.37 3.301e-05 4846800.0 32415.0 26945.0 30663.0 25917.0 34271.0 26665.0 23369.0 27305.0 31873.0 26951.0 True False 31952.75615581703 26882.610507995854 28142.0065026029 27823.02263657756 32255.247159378403 25524.600109150968 24578.932474604822 28573.689981803258 28283.12710243053 31609.444440049854 1.0108610487102454 0.8504613410394205 0.8903037367827435 0.8802123267097091 1.0204306886998085 0.80749916872347 0.7775819192653314 0.9039605247095002 0.8947682442211858 1.0 14.948068058555592 -6.79531735041375 24.999640856749686 0.8645608147025418 0.9209883754068858 0.09518566654357441 0.0756136074588655 429.58415387931296 317000.95031870133 0.026520314368934206 0.0233900419106731 1.6020742849974697e-07 6.79531735041375 0.05642756070434407 LEGEPVALR ddPTM_PC-9_AZD4547_30min_R2 1 LEGEPVALR 9 0 C9JNR0;P27930-2;P27930 C9JNR0 IL1R2 Interleukin-1 receptor type 2;Interleukin-1 receptor type 2, membrane form;Interleukin-1 receptor type 2, soluble form 0 96.19 0.023887000000000002 3104600.0 15731.0 14443.0 20985.0 21068.0 18230.0 20837.0 19544.0 22918.0 18284.0 15460.0 False True 20733.130774873243 19111.417301741283 20706.725188644577 16211.098097355278 15699.07917270543 19534.059096025 21283.378138255204 19376.549703248358 19250.4549124742 14918.75010565777 1.3897364476270995 1.281033408723261 1.3879664879426985 1.0866257550092886 1.0523052575799716 1.3093629799869715 1.4266193875171702 1.2988051657155928 1.2903530641734982 1.0 13.864839051073975 -10.751410423862119 2.916999806273246 0.998447784871053 1.2767983087244474 0.3419599261852906 0.11656281684753791 10300586.557313507 13411592.543383546 144641.96065605155 0.03363578076451168 1.7725136002047656e-11 10.751410423862119 0.2783505238533944 LEGEPVALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LEGEPVALR 9 0 C9JNR0;P27930-2;P27930 C9JNR0 IL1R2 Interleukin-1 receptor type 2;Interleukin-1 receptor type 2, membrane form;Interleukin-1 receptor type 2, soluble form 0 ;; 94.662 0.024782 3088400.0 37022.3 54838.0 52293.0 49434.0 53961.0 40505.0 45729.0 38779.6 39941.0 36641.7 False True 43289.444166244 60281.95422828366 53539.86344230688 46664.373247190386 43387.72941227964 38380.84649502273 41397.218070710274 37761.6765903826 40525.061564051684 43284.5501544624 1.000113066019264 1.3926898630842979 1.236927801057145 1.0780838216099502 1.002383743332183 0.8867100699454971 0.9563970960304055 0.8724054300120659 0.9362477239439156 1.0 15.401564545540205 -6.107856002229152 1.9904284385421733 0.9271731081840859 1.2271042137453976 0.605076822206971 0.09703524481934701 0.20196129724836287 1.5822682654522238 0.030994268450962134 0.045307015739607534 7.800887194182799e-07 6.107856002229152 0.29993110556131164 LEGEPVALR ddPTM_PC-9_Lapatinib_30min_R1 2 LEGEPVALR 9 0 C9JNR0;P27930-2;P27930 C9JNR0 IL1R2 Interleukin-1 receptor type 2;Interleukin-1 receptor type 2, membrane form;Interleukin-1 receptor type 2, soluble form 0 ; 90.777 0.038296 6109400.0 31133.0 35367.0 37068.0 35646.0 36497.0 33350.0 30372.0 35674.0 36436.0 27786.0 False True 30689.037710907047 35285.10988444199 34020.41212661787 38267.52575157016 34350.318215862775 31923.6982426471 31944.513548662668 37331.54427433982 32332.193991910368 32588.773077482278 0.9417058334151315 1.0827382117316589 1.0439304372009268 1.1742548779171962 1.0540537421949667 0.9795919032221952 0.9802306295088854 1.1455338986092312 0.9921267644853682 1.0 14.992087417162843 -6.536048448429411 24.85239981072796 1.0251033138933192 1.0676790872113897 0.07020093693273233 0.06951577998174675 632.5659527271482 1193700.052797507 0.023282605858030804 0.023296230798705745 2.91039242638122e-07 6.536048448429411 0.0425757733180705 LEGEVT(ph)PNSLSTSYK ddPTM_PC-9_AZD4547_30min_R2 2 LEGEVTPNSLSTSYK 15 0 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;A0A0A0MQZ8;H0Y7Y3 Q8IWZ3-6 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 1 LEGEVT(0.993)PNS(0.007)LSTSYK;LEGEVT(0.979)PNS(0.02)LS(0.001)TSYK 125.98 0.00026295 0.0 19765.3 22607.0 24092.0 34210.0 33694.0 30234.0 20094.7 31051.0 24138.0 29112.0 True False 26050.254256220356 29914.27064601988 23772.524338566844 26323.41303923123 29016.169700775466 28343.463200519265 21883.089371407947 26252.781430995907 25413.88540129633 28092.79774100315 0.9272929843579952 1.0648377182582345 0.846214199017615 0.9370164296883327 1.032868636590958 1.00892276596397 0.7789572819750966 0.9345022049077858 0.9046405999002092 1.0 14.77791268810343 LEGEVT(ph)PNSLSTSYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LEGEVTPNSLSTSYK 15 0 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;A0A0A0MQZ8;H0Y7Y3 Q8IWZ3-6 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 1 LEGEVT(0.986)PNS(0.014)LSTSYK 109.1 0.0025149 0.0 9530.6 13332.0 9642.1 13113.0 13844.0 13113.0 12130.0 15024.0 8791.3 10894.0 True False 11143.942342069653 14655.512851881498 9872.004231867877 12378.321122919599 11131.367579985534 12425.331195882804 10980.958586405031 14629.635919243827 8919.856130994403 12868.995963143456 0.865952742077601 1.138823331194958 0.7671153414097803 0.9618715522462561 0.8649756058565521 0.9655245235501434 0.8532879035671683 1.1368125346486089 0.693127587928436 1.0 13.651611878679242 -5.258561174845579 24.989490970356844 0.9110934766842201 1.002388009739967 0.07786345398353112 0.1324126064875177 646.1536399735609 5610031.843512003 0.031166333431637987 0.07547429025265903 5.513645315450749e-06 5.258561174845579 0.09129453305574675 LEGEVTPNSLS(ph)TSYK ddPTM_PC-9_Lapatinib_30min_R1 1 LEGEVTPNSLSTSYK 15 0 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;A0A0A0MQZ8;H0Y7Y3 Q8IWZ3-6 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 1 LEGEVTPNS(0.097)LS(0.788)T(0.11)S(0.004)YK 106.3 0.004314899999999999 0.0 12259.0 20280.0 14642.0 17428.0 20155.0 17841.0 22426.0 20280.0 18459.0 17827.0 True False 12084.184411974731 20233.04290599949 13438.191279754476 18709.713258103693 18969.522526254597 17077.982019402294 23587.108548739274 21222.28283577989 16379.953038112666 20908.37319701565 0.5779590931397552 0.967700486085041 0.6427181662164214 0.8948430890249375 0.9072691762055503 0.8168010900934135 1.1281178275556116 1.0150135850267414 0.7834159493791057 1.0 14.351793195092409 -6.116085439807716 0.8561258320987803 0.971041080184688 0.7283142431013143 0.3270465211982647 0.13310278569577053 0.8368163263652224 1.2761805029463449 0.06438605877465887 0.1287513720931645 7.654460040469402e-07 6.116085439807716 -0.24272683708337373 LEGGSGGDSEVQR ddPTM_PC-9_AZD4547_30min_R2 2 LEGGSGGDSEVQR 13 0 P62195-2;P62195;J3QQM1 P62195-2 PSMC5 26S protease regulatory subunit 8 0 ; 127.51 0.00053532 3246200.0 20912.0 19334.7 23485.0 36960.0 33970.0 28317.0 22620.0 28672.0 22378.0 22262.0 False True 27561.581003378633 25584.263664334085 23173.573555173603 28439.443026307705 29253.851864882276 26546.333513564336 24633.136179253623 24241.401217014423 23560.855394407532 21482.61415602543 1.282971467215417 1.1909287891370626 1.078712925106179 1.3238353032715542 1.3617454399364695 1.2357124380097213 1.1466544993242611 1.1284195229198961 1.096740611886808 1.0 14.390881940864283 -7.999818147259395 1.083033903685431 1.0194599660783545 1.2420425465840685 0.5303946832036396 0.07528735612468196 0.45083586744148885 0.9729677710211362 0.07654105921210039 0.02747918158363501 1.000418819089871e-08 7.999818147259395 0.222582580505714 LEGGSGGDSEVQR ddPTM_PC-9_Lapatinib_30min_R1 2 LEGGSGGDSEVQR 13 0 P62195-2;P62195;J3QQM1 P62195-2 PSMC5 26S protease regulatory subunit 8 0 ; 136.49 0.00025590000000000004 8123700.0 29167.0 24848.0 31209.0 28953.0 26625.0 32153.0 28045.0 26386.0 25037.0 26818.0 False True 28751.073231427265 24790.465982656577 28643.116490223867 31082.30020437666 25058.96984676401 30777.891142303797 29497.0328747611 27611.989886828815 22217.069408701816 31453.455567261197 0.9140831337257981 0.7881635113078038 0.910650864067142 0.9881998541593993 0.7967000571106411 0.9785217740698554 0.9377994354764483 0.8778682465518723 0.7063474905385845 1.0 14.940930903995502 -10.788965186183155 3.4666945368390163 1.000326303969071 0.8815560840293316 0.15548380256642347 0.08513368226893961 71807896.41150245 107775723.56142981 255287.78313053364 0.021129814930898567 1.6256790678481817e-11 10.788965186183155 -0.11877021993973946 LEGLTQDLR ddPTM_PC-9_Lapatinib_30min_R1 1 LEGLTQDLR 9 0 Q01094 Q01094 E2F1 Transcription factor E2F1 0 96.19 0.023887000000000002 2748600.0 20721.0 16954.0 16817.0 15864.0 17748.0 17893.0 15646.0 14761.0 21403.0 11167.0 False True 20425.51474023399 16914.744054650655 15434.371175497272 17030.69148075265 16704.09753391053 17127.758100620224 16456.073323534052 15446.849947679833 18992.368756418295 13097.201070907813 1.5595328062576828 1.291477771706702 1.178448058629939 1.3003306117504838 1.2753944482851793 1.3077418608671507 1.2564572563589287 1.179400840229229 1.4501089701222605 1.0 13.676970914017549 -11.761469202142683 2.194031345497454 1.7563302715176257e-05 1.2995861428412783 0.4132468995198322 0.11042034017180108 1859578.7384982915 359761.28924267105 9214444.029644772 0.026842829022160085 1.7319318458003852e-12 11.761469202142683 1.2995685795385632 LEGNS(ph)PQGSNQGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LEGNSPQGSNQGVK 14 0 P61006 P61006 RAB8A Ras-related protein Rab-8A 1 LEGNS(0.833)PQGS(0.167)NQGVK 97.20299999999999 0.0027598 4510700.0 19198.0 19006.0 18768.0 14901.0 21072.0 12955.0 16585.0 10721.0 13383.0 11509.0 True False 22447.84222221615 20892.79007372186 19215.500298036368 14066.145279693821 16943.092866617677 12275.616994025913 15013.948734998141 10439.58510983847 13578.701056851458 13595.490594806124 1.6511241036635989 1.5367441084989988 1.4133730713165475 1.0346184406958805 1.2462288689376486 0.9029182807655032 1.104332986757676 0.7678711582373274 0.998765065678389 1.0 13.730840591664133 -5.404933657741227 0.6666083826121859 0.9347504133522647 1.8497434963872939 0.824934594188009 0.11418259610418774 0.6139967162054311 0.35248196455737735 0.05529569189457595 0.3803723790504168 3.936101982441716e-06 5.404933657741227 0.9149930830350291 LEGNSPQGS(ph)NQGVK ddPTM_PC-9_AZD4547_30min_R2 1 LEGNSPQGSNQGVK 14 0 P61006 P61006 RAB8A Ras-related protein Rab-8A 1 LEGNS(0.293)PQGS(0.707)NQGVK 141.1 1.5245e-05 0.0 13621.0 19141.0 22800.0 23832.0 18471.0 16950.0 14937.0 20562.0 17298.0 16752.0 True False 17952.194665599684 25327.953927344024 22497.657102744648 18337.900600729576 15906.620482668246 15890.113820493538 16266.364063196788 17384.615367754275 18212.336965433078 16165.517578911968 1.1105239642322648 1.5667889261018477 1.3917065749934912 1.1343837592092627 0.9839846082886047 0.9829635050610631 1.0062383702713222 1.0754134708580336 1.126616384321106 1.0 13.980632079192574 -5.880224492124165 3.718415827260696 1.031277530513051 1.3778324209060573 0.6275921518282735 0.11206126840567665 0.13650484190053724 3.5817138757168068 0.0318876790355974 0.04977042440828081 1.3175754916286001e-06 5.880224492124165 0.34655489039300624 LEGPVS(ph)PDVEPGKEETEESK ddPTM_PC-9_AZD4547_30min_R2 4 LEGPVSPDVEPGKEETEESK 20 1 O14686;O14686-3;A0A3B3ISC8 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 LEGPVS(1)PDVEPGKEETEESK;LEGPVS(1)PDVEPGKEETEESK;LEGPVS(1)PDVEPGKEETEESK;LEGPVS(1)PDVEPGKEETEESK 97.352 0.00021243 38045200.0 151227.0 155215.0 146305.0 118274.0 133675.0 173468.0 160786.0 158686.0 161135.0 154062.0 True False 199314.04028299282 205385.21335524277 144364.90010601107 91007.75661508442 115116.53364845856 162621.01853766228 175095.6425162456 134164.72494151606 169652.26713637754 148668.33627282357 1.340662344651712 1.3814993730631193 0.9710534450394657 0.6121529230546757 0.7743177635162771 1.0938510688599752 1.1777601532778632 0.902443171862153 1.1411459318751374 1.0 17.181737886006957 -5.27295773804739 8.114000264002149 0.9489236183808683 1.3617153182459978 0.49759693669753624 0.16132743106399397 0.12744080711401093 67.2021609071461 0.046527475649473723 0.10407711110065798 5.333867977607224e-06 5.27295773804739 0.41279169986512954 LEGPVS(ph)PDVEPGKEETEESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LEGPVSPDVEPGKEETEESK 20 1 O14686;O14686-3;A0A3B3ISC8 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 LEGPVS(1)PDVEPGKEETEESK;LEGPVS(0.999)PDVEPGKEET(0.001)EESK 73.11 0.0014118 16591000.0 82863.0 99640.0 77869.0 94942.0 86415.0 79237.0 108234.0 86452.0 78841.0 78572.0 True False 96890.0692811489 109531.60070218075 79725.69227982711 89622.70754611718 69482.60108526802 75081.67223123349 97981.29197369833 84182.72660346549 79993.90047248206 92816.48162439044 1.043888623932584 1.1800878333810694 0.8589605087861539 0.9655904423182317 0.7486019709996128 0.8089260755980157 1.055645401106765 0.9069803673892315 0.8618501700614037 1.0 16.502093390144722 -5.2663941573656485 24.943056096786506 0.8966217484203111 1.111988234410453 0.4637385872331172 0.09074277347546067 311.8877116384922 1570095.1359930714 0.0240445539039639 0.05267129291983472 5.415092039159436e-06 5.2663941573656485 0.21536648599014196 LEGPVS(ph)PDVEPGKEETEESK ddPTM_PC-9_Lapatinib_30min_R1 4 LEGPVSPDVEPGKEETEESK 20 1 O14686;O14686-3;A0A3B3ISC8 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 LEGPVS(1)PDVEPGKEETEESK;LEGPVS(1)PDVEPGKEETEESK;LEGPVS(1)PDVEPGKEETEESK;LEGPVS(1)PDVEPGKEETEESK 94.671 0.00026805 50014600.0 199218.0 248715.0 203756.0 232063.0 259065.0 250016.0 255500.0 257331.0 220743.0 224030.0 True False 196377.1147878935 248139.11569850455 187003.96820090513 249129.68715947476 243827.30604138694 239323.39849576197 268728.53982889897 269287.537693001 195880.59881315893 262753.2869987889 0.7473821432681017 0.944380633760248 0.7117093389654421 0.9481506016730556 0.927970526368756 0.9108293229338938 1.0227409251406916 1.0248683880184617 0.7454924771847357 1.0 18.00334928660596 -5.79718717487446 24.969040156042073 0.9427736619667397 0.8154796503392451 0.310019031716558 0.09413742031186076 210.09866756057608 146748.3882396758 0.025574799569252574 0.03793504735610173 1.5951914937409357e-06 5.79718717487446 -0.12729401162749465 LEGQATAVT(ph)PNK ddPTM_PC-9_AZD4547_30min_R2 1 LEGQATAVTPNK 12 0 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 LEGQAT(0.044)AVT(0.956)PNK 77.633 0.038206 0.0 31282.0 38792.0 36042.0 25317.0 38874.0 37526.0 41133.0 39568.0 39723.0 36604.0 True False 41229.025293979066 51330.755381094474 35564.05953057557 19480.556793750868 33477.016114084 35179.493287778205 44793.75731482046 33453.67478218563 41822.67668388824 35322.50510139047 1.1672169110212993 1.4532025753483109 1.006838541844406 0.5515055270806378 0.947753168072051 0.9959512550652407 1.2681364808708644 0.9470923618287972 1.1840235159946766 1.0 15.108300043294394 -5.329993793680787 7.8310138770030004 0.9782820710703457 1.30930152543223 0.32001451520153235 0.18779377248797172 0.3282713001429605 34.016954861689285 0.05212982224328288 0.10932730993596568 4.677418255405269e-06 5.329993793680787 0.3310194543618843 LEGQATAVT(ph)PNK ddPTM_PC-9_Lapatinib_30min_R1 1 LEGQATAVTPNK 12 0 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 LEGQAT(0.021)AVT(0.979)PNK 91.07600000000001 0.01614 6186600.0 26649.0 46095.0 40578.0 32519.0 47064.0 42502.0 40297.0 47463.0 37893.0 31948.0 True False 26268.980373171915 45988.269859568376 37241.83347560972 34910.55574020393 44295.78805138413 40684.288537001106 42383.38148526471 49668.30425220021 33625.09130902018 37470.16923196589 0.7010638305514186 1.2273301883124583 0.9939061989567589 0.9316892999357379 1.182161408910726 1.0857780834972381 1.1311233003214554 1.3255425654663993 0.8973829581835604 1.0 15.19345487308428 -6.259150913650906 24.934753857911495 1.1204204452469182 0.9845146376945159 0.1469773768528263 0.15925795372207285 389.4261670161128 4243119.98897531 0.045871108615261044 0.05636789851779878 5.506163286514131e-07 6.259150913650906 -0.13590580755240234 LEGQATAVTPNKNS(ph)SCGGGISSSSSSR ddPTM_PC-9_Lapatinib_30min_R1 1 LEGQATAVTPNKNSSCGGGISSSSSSR 27 1 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 LEGQAT(0.006)AVT(0.212)PNKNS(0.448)S(0.193)CGGGIS(0.04)S(0.05)S(0.024)S(0.012)S(0.012)S(0.003)R 47.73 0.019563 4546200.0 16622.0 19719.0 17707.0 20452.0 25943.0 18213.0 15890.0 15575.0 21536.0 13230.0 True False 16384.967231898525 19673.341867031737 16251.198810996624 21956.10830587198 24417.083745900443 17434.07244657665 16712.706449632875 16298.671359332915 19110.388895866206 15516.787872133109 1.0559509717423279 1.2678746419137084 1.0473300882189964 1.4149905564735707 1.5735913867683622 1.1235619504657166 1.0770725608518203 1.0503895196378887 1.231594390111301 1.0 13.921542315904032 -6.9710634200069475 24.998371118595067 1.0948706384671587 1.275328089015723 0.24560385657682626 0.1544735334105972 325.2366597282283 280971.7245276158 0.057475478918658264 0.05068791578586446 1.0688987765767425e-07 6.9710634200069475 0.18045745054856432 LEGQGDVPT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 LEGQGDVPTPK 11 0 Q9Y2Z0-2;Q9Y2Z0 Q9Y2Z0-2 SUGT1 Suppressor of G2 allele of SKP1 homolog 1 LEGQGDVPT(1)PK;LEGQGDVPT(1)PK 108.66 0.005275 26366000.0 128505.0 148906.0 107942.0 135368.0 139445.0 142038.0 137738.0 189345.0 169705.0 147246.0 True False 169366.9169299529 197036.95248446235 106510.61855195006 104160.99901475171 120085.46874590812 133156.34140621018 149996.41516613757 160086.0809652481 178675.25984037603 142090.9623581944 1.191961220608803 1.386695882794823 0.7495946032334517 0.7330585794202324 0.8451309411444969 0.9371204135456476 1.0556365632038895 1.126645061082 1.257470967013067 1.0 17.11645526986436 -9.53903298019109 10.946745225043207 1.0000297098062558 1.0201124919598763 0.0 0.20638596548426408 0.0 0.0 0.22097802998931254 0.05359504462275546 2.8904603733477427e-10 9.53903298019109 0.02008278215362047 LEGQGDVPT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LEGQGDVPTPK 11 0 Q9Y2Z0-2;Q9Y2Z0 Q9Y2Z0-2 SUGT1 Suppressor of G2 allele of SKP1 homolog 1 LEGQGDVPT(1)PK 82.55 0.033792 9750700.0 49318.0 67765.0 48063.0 49255.0 65005.0 42883.0 67443.0 43629.0 39523.0 44821.0 True False 57666.56332509927 74492.26135671673 49209.00419994256 46495.402036864536 52267.73689229697 40634.139988792966 61054.31079496401 42483.78497874659 40100.949104830004 52946.69249715921 1.0891438275996805 1.406929457599519 0.9294065762952579 0.878154986534035 0.9871766191080081 0.767453793095256 1.1531279465330115 0.802387891954271 0.7573834589758666 1.0 15.692252943521845 -5.329099994205291 8.104968763985482 0.906919511680004 1.247239647736875 0.5045757177390484 0.13423975899076346 0.22022441349732277 24.30228656517456 0.03367956356796426 0.07055232550655709 4.687054525556512e-06 5.329099994205291 0.34032013605687106 LEGQGDVPT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 LEGQGDVPTPK 11 0 Q9Y2Z0-2;Q9Y2Z0 Q9Y2Z0-2 SUGT1 Suppressor of G2 allele of SKP1 homolog 1 LEGQGDVPT(1)PK 96.059 0.014577000000000001 11164000.0 39784.0 70477.0 63765.0 66384.0 96281.0 102210.0 111180.0 82702.0 89342.0 91970.0 True False 39216.67286450795 70313.81483659413 58522.487840018075 71266.10081053208 90617.94087572918 97838.71656314716 116936.35639208196 86544.63683849468 79279.36314703192 107866.89195767812 0.3635654291392276 0.6518572433159746 0.5425435625138763 0.6606855868109516 0.8400904043038839 0.9070319426792649 1.084080149801315 0.8023280848070669 0.7349740194436807 1.0 16.71889259470251 -6.113910461034862 1.637171381841094 0.9057260136111972 0.5183558108956339 0.7083044852292024 0.1105623363840255 0.22162840622727387 1.1848664731515308 0.0397638585694776 0.06059601996682638 7.69289029092695e-07 6.113910461034862 -0.3873702027155633 LEGVDGGQS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 LEGVDGGQSPR 11 0 O00418;H3BRH4 O00418 EEF2K Eukaryotic elongation factor 2 kinase 1 LEGVDGGQS(1)PR;LEGVDGGQS(1)PR 132.24 0.00011812 144010000.0 104602.0 120277.0 150520.0 196036.0 174608.0 152633.0 135596.0 174362.0 138437.0 135577.0 True False 137863.26014323908 159154.18810507082 148524.00645197913 150842.92892600803 150366.69315346944 143088.8343813208 147663.78131574148 147418.35934016004 145754.49719526316 130830.49049642739 1.053754821373262 1.2164915647810468 1.1352400032164895 1.152964636558686 1.1493245388205247 1.0936963840644482 1.1286648911537465 1.1267890136373495 1.1140713196305208 1.0 16.997339279506427 -11.505388792734283 0.2909495132087923 0.8562032274027671 1.1458453040996748 0.5015991569411276 0.03933363783579505 24.873836577515924 1.102566948490607 2.447232719398551 0.04199691803315901 3.123282064536063e-12 11.505388792734283 0.28964207669690767 LEGVDGGQS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LEGVDGGQSPR 11 0 O00418;H3BRH4 O00418 EEF2K Eukaryotic elongation factor 2 kinase 1 LEGVDGGQS(1)PR;LEGVDGGQS(1)PR;LEGVDGGQS(1)PR;LEGVDGGQS(1)PR 159.58 0.0010321 103798000.0 233935.0 237692.0 260539.0 271194.0 317735.0 265123.0 256289.0 239114.0 242810.0 197672.0 True False 273535.5750731395 261288.49090829666 266751.2378596595 255999.87940281117 255477.10762978217 251219.48315763238 232011.45054832348 232837.51086222532 246360.63689861013 233508.36882930918 1.1714165811037358 1.1189684216384308 1.1423626450607014 1.0963199335692457 1.0940811625322593 1.0758478782457246 0.9935894448302197 0.9971270495766503 1.0550398606000102 1.0 17.83311473080508 -6.640184559363187 0.8848623374082525 1.0076681389974438 1.1452305746154303 0.833211215081748 0.024264118478631063 0.2289505446233625 0.39306538702606614 0.01451235817384726 0.015382730511473796 2.2898943241441353e-07 6.640184559363187 0.13756243561798653 LEGVDGGQS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 LEGVDGGQSPR 11 0 O00418;H3BRH4 O00418 EEF2K Eukaryotic elongation factor 2 kinase 1 LEGVDGGQS(1)PR;LEGVDGGQS(1)PR;LEGVDGGQS(1)PR 148.89 0.00029502 125666800.0 151495.0 162941.0 190216.0 144763.0 161337.0 146235.0 148436.0 142768.0 177413.0 119216.0 True False 149334.65351921963 162563.72012556528 174577.1747349937 155409.3539352118 151847.4748607462 139980.86994043482 156121.289777074 149401.52248020857 157430.87969828697 139822.32675466553 1.068031529622909 1.16264493588926 1.248564365842013 1.1114773837793126 1.0860030610646338 1.0011338903410432 1.116569101664335 1.0685097719933587 1.1259352018545485 1.0 17.093235222320438 -5.995332849983091 24.814964575759074 1.0717339148103822 1.163367442096073 0.3548939810267788 0.05624950591466166 135.08887502649492 718244.7208408291 0.015893346024864075 0.02347580536157912 1.0108044611997004e-06 5.995332849983091 0.09163352728569074 LEIS(ph)PDSSPER ddPTM_PC-9_AZD4547_30min_R2 1 LEISPDSSPER 11 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 LEIS(0.901)PDS(0.099)SPER 161.99 0.0013754000000000001 19488000.0 22390.0 33368.0 31582.0 40730.0 37557.0 26718.0 20194.0 31767.0 26679.0 27649.0 True False 29509.55425906885 44153.5534531955 31163.202044687783 31340.327772227065 32342.858831009216 25047.31923633902 21991.22687903834 26858.140083039096 28089.197473742013 26681.01692570062 1.1060131006717224 1.6548677127319076 1.1679915398827874 1.1746301821816372 1.2122048766385212 0.9387692870211429 0.824227462554292 1.0066385459681584 1.0527783686792296 1.0 14.70352603429181 -6.2332633719298425 1.1435525917855436 0.9588419009116219 1.356036252229294 0.4834610203942562 0.15276208903024388 0.39252363547589075 1.060303193927487 0.06330560954310174 0.09677449716220039 5.84435553732441e-07 6.2332633719298425 0.397194351317672 LEIS(ph)PDSSPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LEISPDSSPER 11 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 LEIS(0.828)PDS(0.172)S(0.001)PER 162.68 0.0014532 12683000.0 77504.0 87267.0 96014.0 98052.0 118130.0 91556.0 78343.0 86201.0 69711.0 64635.0 True False 90623.8964262236 95930.29103248885 98303.33789512253 92558.46432887317 94983.27450330029 86754.64218487358 70921.78388579807 83938.31508750931 70730.39149474497 76352.81384962144 1.186909713697119 1.2564080640358022 1.2874880824789658 1.2122469318703712 1.2440048992873 1.1362337261824924 0.9288692886352571 1.0993480247214946 0.9263626044489996 1.0 16.220393705557697 -7.015818342867362 3.4434406969585005 0.9974507832033196 1.238981514313597 0.8348191069839959 0.0519735883158017 0.09057782810915219 2.2563861445469633 0.019406252495354125 0.01565323670494127 9.642322593242821e-08 7.015818342867362 0.24153073111027734 LEIS(ph)PDSSPER ddPTM_PC-9_Lapatinib_30min_R1 2 LEISPDSSPER 11 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 LEIS(0.868)PDS(0.131)S(0.001)PER;LEIS(0.863)PDS(0.136)S(0.002)PER 177.04 0.00070506 33854000.0 89533.0 76817.0 78687.0 53579.0 77932.0 65874.0 63545.0 64412.0 93690.0 64811.0 True False 88256.24300165873 76639.13495612255 72217.65860060386 57519.378394304455 73348.19298020701 63056.722579794136 66835.04917192708 67404.81666756676 83137.64560056203 76013.49499477088 1.161060190795464 1.0082306432745227 0.9500636512710257 0.7566995623377313 0.9649364627327395 0.8295464191474413 0.8792524166468704 0.8867480264156209 1.0937221819136356 1.0 16.213967948549218 -4.872719932621836 1.963080658478696 0.9067829238315119 1.2068234827305686 0.4090322023477271 0.08835710758592298 0.5760413456582347 2.823796260487704 0.02363597244468546 0.29713232771113407 1.340540895373064e-05 4.872719932621836 0.3000405588990567 LEISPDS(ph)SPER ddPTM_PC-9_AZD4547_30min_R2 1 LEISPDSSPER 11 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 LEIS(0.128)PDS(0.871)SPER 150.51 0.00033797 23003000.0 31359.0 39617.0 44774.0 44190.0 34422.0 27872.0 31073.0 49017.0 36723.0 28346.0 True False 41330.5096922796 52422.420497340194 44180.26750518808 34002.6782286942 29643.099466970194 26129.159433911253 33838.4368036228 41442.54894860476 38664.1028085096 27353.61516785091 1.5109706500826967 1.9164713759281444 1.6151527772136596 1.2430780363049794 1.08369951412529 0.9552360546704344 1.2370736590384437 1.5150666079894541 1.4134915100345518 1.0 14.73944389776138 -5.7147266987851495 3.9284816050249765 1.2111054716080176 1.7234043386638849 0.5812971036146741 0.185498355056629 0.16210117443888977 5.177632457610322 0.056293405664654475 0.09842614112440276 1.9287382850227116e-06 5.7147266987851495 0.5122988670558672 LEISPDS(ph)SPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LEISPDSSPER 11 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 LEIS(0.096)PDS(0.867)S(0.037)PER 140.01 0.00011688 12789000.0 33774.0 36587.0 41697.0 36428.0 39889.0 35573.0 34709.0 40419.0 36042.0 27297.0 True False 39491.27113309345 40219.11556494065 42691.214616753095 34387.057261169466 32073.036795582426 33707.489257312525 31421.112248601166 39358.04407747045 36569.04606523503 32245.73001706689 1.2246976921344832 1.2472695002920895 1.323933885018502 1.0664065363993689 0.99464446233988 1.0453318699707514 0.9744270708701812 1.2205660736053792 1.1340740633218698 1.0 14.97682051090528 -5.7728027759147045 24.861326282057345 1.0642216144402938 1.2634972660586103 0.6241609373354648 0.07220412161038392 136.07813050914245 297717.5178578373 0.021765109072597905 0.03260929626890399 1.6873191056191303e-06 5.7728027759147045 0.1992756516183165 LEISPDSS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 1 LEISPDSSPER 11 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 LEIS(0.005)PDS(0.161)S(0.834)PER 78.964 0.017806 2358200.0 24728.0 20667.0 23473.0 21991.0 26975.0 23872.0 19196.0 19683.0 29470.0 17740.0 True False 24375.374185440174 20619.14683127669 21543.14054840029 23608.291499825486 25388.383534890498 22851.050208349956 20189.874953250637 20597.544036324245 26150.77826714233 20806.33536293584 1.1715361576292853 0.9910032916227715 1.0354125401043466 1.1346684117127621 1.2202237007155554 1.0982736656766836 0.9703715046916259 0.9899650119557559 1.2568661328859967 1.0 14.344735263926419 -9.909212690276679 12.511012857742447 1.000000446427816 1.0895552758077602 0.08057818679076056 0.09521877539093063 0.0 0.0 0.09461529426525311 0.022947579532619743 1.2325010834508558e-10 9.909212690276679 0.08955482937994419 LEKPETQS(ph)SPITVQSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LEKPETQSSPITVQSSK 17 1 Q96CB8;A0A087WXN4;E9PGI3 Q96CB8 INTS12 Integrator complex subunit 12 1 LEKPET(0.004)QS(0.488)S(0.488)PIT(0.019)VQSSK 84.166 0.0016284000000000003 12260000.0 39853.0 35183.0 41581.0 48273.0 51363.0 40718.0 46375.0 37688.0 41922.0 32301.0 True False 46599.325767370545 38675.73572365336 42572.448736820654 45568.42031317758 41298.7888623806 38582.67640005767 41982.02427407526 36698.729933736766 42535.02994136791 38156.9156054247 1.221255047164913 1.013597014066695 1.115720389379906 1.1942375213026706 1.0823408602897984 1.011158155418947 1.1002467995108796 0.9617844983392572 1.1147397337147655 1.0 15.219656936097188 -6.520835914134429 13.253321809266518 1.0399538729252569 1.127522405455189 0.3254176587902474 0.06642222548947083 0.2801727870344769 1727.3252805107397 0.02068874212986611 0.021415146891984385 3.0141446182271805e-07 6.520835914134429 0.08756853252993202 LEKPETQSS(ph)PITVQSSK ddPTM_PC-9_AZD4547_30min_R2 2 LEKPETQSSPITVQSSK 17 1 Q96CB8;A0A087WXN4;E9PGI3 Q96CB8 INTS12 Integrator complex subunit 12 1 LEKPET(0.003)QS(0.056)S(0.915)PIT(0.023)VQS(0.003)SK;LEKPET(0.014)QS(0.314)S(0.669)PIT(0.003)VQSSK 66.977 0.0091552 59206000.0 219465.0 174603.0 229025.0 324350.0 250650.0 260240.0 190348.0 229930.0 198978.0 235012.0 True False 289250.30484441906 231040.00520223888 225987.97885772365 249576.11865754623 215851.5740339338 243967.1516604861 207288.60324706312 194399.6017657687 209495.5708583621 226784.30141208545 1.2754423610602033 1.0187654249595544 0.9964886345774224 1.1004999777477815 0.9517923978420094 1.075767370763367 0.914034181186126 0.8572004347537657 0.9237657525407443 1.0 17.790961251141994 -1.5228787452803376 0.5159214017162368 0.9465008867745527 10.952963722446414 0.6051052506564094 0.0707333774996004 85.85893434686272 0.8721821259682917 0.03959800181276124 938.3247937318752 0.029999999999999995 1.5228787452803376 10.006462835671861 LEKPETQSS(ph)PITVQSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LEKPETQSSPITVQSSK 17 1 Q96CB8;A0A087WXN4;E9PGI3 Q96CB8 INTS12 Integrator complex subunit 12 1 LEKPET(0.006)QS(0.241)S(0.728)PIT(0.024)VQS(0.001)S(0.001)K;LEKPET(0.019)QS(0.428)S(0.496)PIT(0.057)VQSSK;LEKPET(0.001)QS(0.079)S(0.918)PIT(0.001)VQSSK 76.678 0.0038546 58808000.0 380592.0 328935.0 367347.0 448065.0 499948.0 402788.0 405695.0 419814.0 378071.0 341852.0 True False 445018.7085653552 361589.49294431676 376105.9456512562 422961.3706963306 401986.77830674796 381665.08821225044 367264.6326225544 408794.32732970186 383599.57313493895 403827.0615010573 1.1020031864907351 0.8954067902241615 0.9313539916152238 1.0473824342631957 0.9954428928376695 0.9451201382927904 0.9094601814385657 1.0123004778584694 0.9499105179060285 1.0 18.62337806709037 -6.750297849966134 24.795112043100882 0.9607584118204233 0.9882728413436153 0.05779673870873825 0.05961042949161702 741.1792912116227 1649469.549833591 0.019896860823274992 0.019715026414080485 1.7770602398710548e-07 6.750297849966134 0.02751442952319194 LEKPETQSS(ph)PITVQSSK ddPTM_PC-9_Lapatinib_30min_R1 3 LEKPETQSSPITVQSSK 17 1 Q96CB8;A0A087WXN4;E9PGI3 Q96CB8 INTS12 Integrator complex subunit 12 1 LEKPET(0.001)QS(0.131)S(0.859)PIT(0.008)VQS(0.001)SK;LEKPETQS(0.032)S(0.915)PIT(0.053)VQSSK;LEKPETQS(0.063)S(0.937)PITVQSSK 132.01 1.1745999999999999e-05 47433000.0 244217.0 191108.0 217998.0 181304.0 199093.0 183932.0 177449.0 174134.0 189548.0 157416.0 True False 240734.4207960878 190665.50116764038 200075.04593661544 194637.7009724139 187382.74117189797 176065.65712643389 186636.44095537483 182224.90134742073 168199.10821107213 184625.14585636507 1.3039091705491446 1.032716861418079 1.08368253418887 1.0542318061259024 1.014936184899094 0.9536385539996253 1.0108939391201592 0.9869993629642861 0.9110303335490817 1.0 17.494239535175943 -1.5228787452803376 0.6825451801400495 0.9832815598250162 33.28472151825635 0.8035968191555585 0.044661224870499415 113.41117098317582 0.6453499441361124 0.018004499665272556 5572.948724625689 0.029999999999999995 1.5228787452803376 32.30143995843133 LEKVPDS(ph)PENELK ddPTM_PC-9_AZD4547_30min_R2 1 LEKVPDSPENELK 13 1 A0A0U1RR46;A0A0X1KG69;A0A087WUZ6;A0A2R8Y549;Q8NI35-4;Q8NI35-3;Q8NI35-2;Q8NI35 A0A0U1RR46 INADL InaD-like protein 1 LEKVPDS(1)PENELK 93.34200000000001 0.0019672 15024000.0 47713.0 38358.0 40646.0 48051.0 52878.0 48869.0 42109.0 49577.0 39730.0 44811.0 True False 62884.741507947816 50756.47336842704 40107.00748237538 36973.58433054956 45536.80244071957 45813.213704642956 45856.61942405794 41916.0138161246 41830.04668959746 43242.180529406876 1.4542453858260687 1.1737722924011675 0.9274973415158975 0.8550351503529209 1.0530644357712775 1.0594566033386694 1.0604603852683403 0.9693316410725307 0.9673436024150287 1.0 15.400151653770127 -4.889463297754416 2.746951927722052 0.9893035259127916 1.4893065552055695 0.8440763345785747 0.06215423371572474 0.14146867066154217 1.719994509516937 0.018074195595035432 0.14532026081862245 1.2898425579436454e-05 4.889463297754416 0.500003029292778 LEKVPDS(ph)PENELK ddPTM_PC-9_Lapatinib_30min_R1 2 LEKVPDSPENELK 13 1 A0A0U1RR46;A0A0X1KG69;A0A087WUZ6;A0A2R8Y549;Q8NI35-4;Q8NI35-3;Q8NI35-2;Q8NI35 A0A0U1RR46 INADL InaD-like protein 1 LEKVPDS(1)PENELK;LEKVPDS(1)PENELK 93.427 0.0019473 27383800.0 170351.0 123898.0 94727.0 107428.0 112525.0 99776.0 86468.0 84252.0 101727.0 96799.0 True False 167921.7635014525 123611.12179327047 86938.91171679452 115328.61348930244 105906.50073266172 95508.81306921599 90944.88994882669 88166.6554970478 90269.43402720014 113530.57817344017 1.4790884200811445 1.0887914408788644 0.7657752925734098 1.0158374540567865 0.9328456036828142 0.8412606947469923 0.8010607486724024 0.7765895049204804 0.7951111980535845 1.0 16.79272139783594 -4.849514114290313 2.5486663325329544 0.862648927843514 1.5624269049658042 0.8229439995455132 0.08708552420728982 0.16944548447881855 1.6014395997311233 0.023548491308657965 0.2442596236616094 1.4141187663762879e-05 4.849514114290313 0.6997779771222902 LELCSDDQGSLS(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LELCSDDQGSLSPAR 15 0 H3BRS1;Q12968;I3L3K7;H3BR83;Q12968-5;Q12968-6;Q12968-4;Q12968-3;Q12968-2 H3BRS1 NFATC3 Nuclear factor of activated T-cells, cytoplasmic 3 1 LELCS(0.003)DDQGS(0.003)LS(0.994)PAR 85.176 0.0276 0.0 56980.0 64455.0 74355.0 100020.0 113140.0 96595.0 130480.0 117530.0 111470.0 98954.0 True False 66625.5885937011 70853.66643174493 76127.90519290789 94416.20366921516 90971.0291822857 91529.38815422099 118119.98980660566 114444.96203332825 113100.0378694784 116893.5768805668 0.5699679175851912 0.606138235500638 0.651258240396645 0.807710792917926 0.778238048744399 0.783014692481683 1.010491705008667 0.9790526142446615 0.9675470704864788 1.0 16.834836132645634 -6.1996369339506625 0.48967017815268404 1.0218419125988354 0.5054473808839981 0.9105746776691417 0.047802346638132674 0.40105242016538967 0.18025032990675968 0.0422473234434661 0.10263725460569756 6.314850393522433e-07 6.1996369339506625 -0.5163945317148373 LELGLHECSLPVSPLGS(ph)IATR ddPTM_PC-9_AZD4547_30min_R2 1 LELGLHECSLPVSPLGSIATR 21 0 Q96MT8-3;Q96MT8-2 Q96MT8-3 1 LELGLHECSLPVS(0.166)PLGS(0.417)IAT(0.417)R 106.72 4.0532e-05 4094200.0 12726.0 10148.0 20353.0 22800.0 18249.0 17236.0 9441.0 19101.0 11497.0 16635.0 True False 16772.60328275615 13428.142545043993 20083.10592158605 17543.812256488523 15715.441350669307 16158.230195281809 10281.230710359567 16149.379347314201 12104.707948409314 16052.613713299937 1.0448518591623297 0.8365081714959905 1.251080121921003 1.0928944388634416 0.9789957966563865 1.006579394724634 0.6404708226325377 1.0060280298113753 0.7540646130654911 1.0 13.970520598031994 -7.028292459251685 24.50874292076494 0.8467691506153967 1.0389524919753659 0.30141728293164494 0.13875063638722437 698.9640984804479 605485.364293718 0.051596683788755815 0.04006363738266759 9.369308536630328e-08 7.028292459251685 0.19218334135996917 LELGLHECSLPVSPLGSIAT(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LELGLHECSLPVSPLGSIATR 21 0 Q96MT8-3;Q96MT8-2 Q96MT8-3 1 LELGLHECS(0.001)LPVS(0.241)PLGS(0.06)IAT(0.698)R 91.416 0.0020902 0.0 5023.5 4140.7 7584.4 6442.9 8647.9 7956.4 9165.3 6708.0 6865.7 7144.8 True False 5873.879331352373 4551.761331067036 7765.240859997176 6081.925201163629 6953.406074469584 7539.152377558298 8297.096432974275 6531.922107713501 6966.097873871706 8440.095681794324 0.6959493769747898 0.5393021006723177 0.9200418043538485 0.7205990821031356 0.8238539391761165 0.893254373148944 0.9830571531163438 0.7739156466914419 0.8253576898302113 1.0 13.043043638910628 -5.3268727945883825 0.83266825395503 0.880762204547197 0.5704878381067855 0.4373425756534127 0.10078493335509078 1.2106563765478533 1.0952709049056109 0.04040464041943905 0.2990950894740139 4.711152964656619e-06 5.3268727945883825 -0.3102743664404115 LELKAS(ph)PNVEAPQPHR ddPTM_PC-9_AZD4547_30min_R2 1 LELKASPNVEAPQPHR 16 1 E9PEM5;A0A494C1L5;P50851-2;P50851;A0A494C0R9;A0A494BZW2 E9PEM5 LRBA Lipopolysaccharide-responsive and beige-like anchor protein 1 LELKAS(1)PNVEAPQPHR 52.599 0.033929 4773900.0 24099.0 24349.0 34894.0 28913.0 41024.0 38756.0 33991.0 43647.0 35281.0 41480.0 True False 31761.980709660555 32219.338079353198 34431.28276066542 22247.554551397054 35328.52572578541 36332.581193336104 37016.133150707756 36902.359058280854 37145.88163241095 40027.797825529364 0.7934980797120709 0.8049240735098346 0.8601842876978223 0.5558026111845645 0.8825997842742475 0.9076837389781037 0.9247606703734075 0.9219182933602424 0.9280021297779126 1.0 15.288714625962353 -6.504738597907437 24.535415005133796 0.926892087154835 0.7591711113017767 0.5512251393226945 0.07783207839604794 483.63745086102693 654143.7730438962 0.024291075595230034 0.027010245705592975 3.127961522429018e-07 6.504738597907437 -0.16772097585305823 LELKAS(ph)PNVEAPQPHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LELKASPNVEAPQPHR 16 1 E9PEM5;A0A494C1L5;P50851-2;P50851;A0A494C0R9;A0A494BZW2 E9PEM5 LRBA Lipopolysaccharide-responsive and beige-like anchor protein 1 LELKAS(1)PNVEAPQPHR 52.008 0.03549 4761100.0 24387.0 29470.0 35089.0 34374.0 37338.0 32918.0 42080.0 34934.0 28453.0 22281.0 True False 28515.23743479453 32395.58683955504 35925.65483577354 32448.136222011613 30021.8869330757 31191.7221311729 38093.877767182465 34017.019515632564 28869.07129721246 26320.36892370105 1.0833904918831527 1.2308181140418346 1.364937358587823 1.232814643140986 1.140633211491253 1.1850792145654645 1.4473154946122189 1.2924218355085748 1.0968338392558148 1.0 14.683892090532323 -8.45740237034875 3.8734474247732282 1.0020184377535037 1.2504341642068821 0.4050251533009672 0.09949303567302428 0.20840233080429268 6.139775260706118 0.10107265683508522 0.026575383016948576 3.4881698958352597e-09 8.45740237034875 0.2484157264533784 LELKAS(ph)PNVEAPQPHR ddPTM_PC-9_Lapatinib_30min_R1 1 LELKASPNVEAPQPHR 16 1 E9PEM5;A0A494C1L5;P50851-2;P50851;A0A494C0R9;A0A494BZW2 E9PEM5 LRBA Lipopolysaccharide-responsive and beige-like anchor protein 1 LELKAS(1)PNVEAPQPHR 59.512 0.020736 5327500.0 39299.0 40844.0 40496.0 38977.0 41035.0 38567.0 32890.0 34111.0 38538.0 23749.0 True False 38738.58905344606 40749.42822744786 37166.575199080566 41843.4986034604 38621.40197791405 36917.5793140681 34592.88326799404 35695.9215883278 34197.444616869056 27853.983006446655 1.3907737735202979 1.462965932664518 1.3343361051982605 1.5022447092674662 1.3865665807642424 1.3253967773845385 1.2419366831661993 1.281537422495956 1.227739839180423 1.0 14.765596021397796 -8.491734085858635 0.36995106958932394 0.9707719188302733 1.4484339299301134 0.8589328778078019 0.05061346462478829 0.5269883250085686 0.19991911957096128 0.08958645611520351 0.049782682826501806 3.2230416232046295e-09 8.491734085858635 0.4776620110998402 LELQGPR ddPTM_PC-9_Lapatinib_30min_R1 3 LELQGPR 7 0 P19338;H7BY16 P19338 NCL Nucleolin 0 ;; 120.62 0.027533 26890600.0 144621.0 124981.0 145132.0 123768.0 134280.0 136203.0 124430.0 119224.0 136285.0 133495.0 False True 142558.6780197571 124691.61417331001 133199.80718572089 132870.3115979448 126381.91440463735 130377.91519470062 130872.37655933417 124763.58228861069 120935.14815532728 156569.43287909363 0.9105141112048611 0.7963981977861517 0.8507395392342049 0.8486350697875376 0.8071940485486223 0.8327162767165499 0.8358743731312912 0.7968578540164726 0.7724058644877131 1.0 17.256443056553614 -4.744744096841953 24.34676436036283 0.8310775294969671 0.9105144341384299 0.10842576243687185 0.05970074423838734 1397.6078235955833 2037979.3736313009 0.013550994325730948 0.35661122435960757 1.7999311920101806e-05 4.744744096841953 0.0794369046414628 LELQGPRGS(ph)PNAR ddPTM_PC-9_AZD4547_30min_R2 3 LELQGPRGSPNAR 13 1 P19338;H7BY16 P19338 NCL Nucleolin 1 LELQGPRGS(1)PNAR;LELQGPRGS(1)PNAR;LELQGPRGS(1)PNAR 124.42 0.00074315 447256000.0 95305.0 35853.0 112525.0 336150.0 238637.0 98842.0 75062.0 94251.0 67721.0 122168.0 True False 125610.00753285181 47441.781106371964 111032.84497747099 258655.81096572892 205506.37172445975 92661.39411476246 81742.37258563799 79686.67362251764 71300.59380483837 117890.93550504539 1.0654763828511318 0.4024209401946903 0.9418268207119207 2.194026282492764 1.743190609558482 0.7859925253608393 0.693372838509197 0.6759355439936032 0.6048013233535408 1.0 16.847093269899055 -6.9643446641706435 23.864880879780124 0.7198305621929312 1.2554147505900404 0.2433366447039177 0.4555527119638376 180.8056075195468 121016.05349173621 0.183553306941039 0.16187798751633697 1.0855637580963217e-07 6.9643446641706435 0.5355841883971092 LELQGPRGS(ph)PNAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LELQGPRGSPNAR 13 1 P19338;H7BY16 P19338 NCL Nucleolin 1 LELQGPRGS(1)PNAR;LELQGPRGS(1)PNAR;LELQGPRGS(1)PNAR;LELQGPRGS(1)PNAR 123.95 0.00077084 1547870000.0 301121.0 48404.3 213061.0 497504.0 460872.0 791590.0 391063.0 759536.0 565801.0 356909.0 True False 352094.83788915235 53209.5590111257 218141.18227834237 469630.46380972967 370567.43999733456 750077.626885447 354018.68158906046 739598.9847949147 574074.769234673 421613.77640991035 0.8351122700194483 0.12620450750971943 0.5173957647585417 1.1138878520732574 0.8789263082263554 1.7790633723414921 0.8396753175467133 1.754209720310102 1.3616129295465282 1.0 18.68556248285772 -5.97723560569507 1.5393490771313718 1.3380581756548109 0.43189265812129835 0.5015527905058508 0.34437236200544963 0.29232432729355545 1.4027286465801334 0.1124573622404676 0.19887145652415786 1.053815044350636e-06 5.97723560569507 -0.9061655175335126 LELQGPRGS(ph)PNAR ddPTM_PC-9_Lapatinib_30min_R1 1 LELQGPRGSPNAR 13 1 P19338;H7BY16 P19338 NCL Nucleolin 1 LELQGPRGS(1)PNAR 56.413999999999994 0.034666 502730000.0 195230.0 44131.0 58092.0 53826.0 36984.0 39605.0 18781.0 21583.0 49202.0 21224.0 True False 192445.98439920312 44028.81738090057 53315.9000016048 57784.543598272285 34808.673833341636 37911.18647376424 19753.388283861234 22585.82497261524 43660.35263997073 24892.540120797665 7.731070572360549 1.768755505353774 2.141842485454487 2.3213598659621493 1.3983576470871715 1.5229938885220284 0.7935465078293604 0.9073330750100842 1.7539532899453922 1.0 14.60342583496669 -4.759954145132412 5.484875421922014 1.5090815473301653 8.043749573105975 0.9389643825266866 0.4761298325115027 0.03779746747667995 3.576939229361522 0.13335500346585769 0.9401956888578424 1.7379843236755382e-05 4.759954145132412 6.53466802577581 LELSDNR ddPTM_PC-9_Lapatinib_30min_R1 1 LELSDNR 7 0 P39687;H0YN26 P39687 ANP32A Acidic leucine-rich nuclear phosphoprotein 32 family member A 0 94.006 0.023538 0.0 35187.0 32242.0 61162.0 38383.0 34755.0 37159.0 29397.0 30864.0 46607.0 26238.0 False True 34685.22692749448 32167.345629942596 56133.49645214746 41205.81386193449 32710.77923095902 35569.79619185975 30919.032819374283 32298.054114571514 41357.62886653218 30773.203340062613 1.1271243537502944 1.0453037753162666 1.8241031273812538 1.3390160720866524 1.0629630873810898 1.155869143643964 1.0047388462520512 1.0495512526810542 1.34394942279831 1.0 14.909387008540357 -6.253435584826224 22.143514167592595 1.1030687255668268 1.3482893042976707 0.21943078720831743 0.21278507166984206 204.06377101580028 564563.3794085949 0.06599598879291704 0.08337228868912436 5.579103460588469e-07 6.253435584826224 0.2452205787308439 LELSSSAS(ph)PQEER ddPTM_PC-9_AZD4547_30min_R2 4 LELSSSASPQEER 13 0 A0A075B6T1;Q9C0C7-4;Q9C0C7-2;Q9C0C7-3;Q9C0C7;Q9C0C7-5;Q9C0C7-6 A0A075B6T1 AMBRA1 Activating molecule in BECN1-regulated autophagy protein 1 1 LELS(0.026)S(0.15)S(0.15)AS(0.674)PQEER;LELSS(0.004)S(0.057)AS(0.939)PQEER;LELSSS(0.001)AS(0.998)PQEER;LELSSS(0.002)AS(0.998)PQEER 153.14 9.814100000000001e-05 42002100.0 61451.0 61111.2 96397.0 108668.0 106526.0 88280.0 81114.0 106685.0 78517.0 96095.0 True False 80991.13973979627 80864.20030535008 95118.71279531914 83616.27150386371 91736.70367260657 82759.83764443491 88332.98886136059 90199.28462741293 82667.24832436754 92730.74329904151 0.8734011705116292 0.8720322670613805 1.025751648388893 0.9017103554774157 0.9892803660245737 0.8924746497237486 0.9525750114662741 0.9727009772426277 0.891476174819166 1.0 16.500760098680516 LELSSSAS(ph)PQEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LELSSSASPQEER 13 0 A0A075B6T1;Q9C0C7-4;Q9C0C7-2;Q9C0C7-3;Q9C0C7;Q9C0C7-5;Q9C0C7-6 A0A075B6T1 AMBRA1 Activating molecule in BECN1-regulated autophagy protein 1 1 LELSSS(0.001)AS(0.999)PQEER;LELSS(0.001)S(0.006)AS(0.994)PQEER;LELS(0.002)S(0.024)S(0.398)AS(0.577)PQEER;LELS(0.002)S(0.013)S(0.012)AS(0.973)PQEER 178.67 5.8488e-05 31437900.0 59029.0 66339.0 80444.0 81967.0 98978.0 88184.0 89170.0 81511.0 75918.0 65494.7 True False 69021.44382410654 72924.69750082266 82362.0900455689 77374.65473059949 79583.9714195181 83559.47580094024 80723.17206510615 79371.42261804333 77028.15712725463 77368.37065424002 0.8921144808976788 0.9425647313515729 1.0645447144498603 1.0000812228085758 1.0286370353484582 1.0800211390565317 1.0433614070258603 1.0258898041520736 0.9956026794398216 1.0 16.239456271159145 -5.078196116431375 3.8643361846983053 1.0316495582219452 0.8997298847304639 0.7483035191237901 0.02672062738477567 0.10335999149650878 2.846005546482486 0.007074475432439574 0.02381785772137965 8.352257661744963e-06 5.078196116431375 -0.13191967349148126 LELSSSAS(ph)PQEER ddPTM_PC-9_Lapatinib_30min_R1 3 LELSSSASPQEER 13 0 A0A075B6T1;Q9C0C7-4;Q9C0C7-2;Q9C0C7-3;Q9C0C7;Q9C0C7-5;Q9C0C7-6 A0A075B6T1 AMBRA1 Activating molecule in BECN1-regulated autophagy protein 1 1 LELSSS(0.002)AS(0.998)PQEER;LELSSS(0.001)AS(0.999)PQEER;LELS(0.001)S(0.022)S(0.005)AS(0.972)PQEER 173.25 0.00019567 34548200.0 76755.0 65141.0 87618.0 70210.0 73107.0 75805.0 67661.0 67043.0 76149.0 62615.0 True False 75660.45962485681 64990.17001675112 80414.3862552609 75373.47761369425 68806.9899938921 72562.99686008578 71164.15551218443 70158.06253250434 67572.29773548085 73437.91932075699 1.0302642058034401 0.8849674748121827 1.0949981562526654 1.026356387964687 0.9369408968868216 0.9880862302640985 0.9690382866289909 0.9553383753435725 0.9201281621330162 1.0 16.16423756373487 -6.258220311651686 24.844629198460336 0.9610529373353667 1.0064088788845504 0.1608022818802508 0.053069179439867796 529.9656076755458 4090254.1710303593 0.01599020727749734 0.019848057823432498 5.517974489691095e-07 6.258220311651686 0.045355941549183765 LENS(ph)PLGEALR ddPTM_PC-9_AZD4547_30min_R2 3 LENSPLGEALR 11 0 D6RI08;D6RDK1;D6RIV2;D6R9T5;D6RG39;D6RIT9;D6RDK6;D6RBN5;Q9NX40-3;Q9NX40-2;Q9NX40-4;Q9NX40 D6RI08 OCIAD1 OCIA domain-containing protein 1 1 LENS(1)PLGEALR;LENS(1)PLGEALR;LENS(1)PLGEALR 134.02 5.6331999999999995e-05 73441900.0 124624.0 104213.0 171207.0 192238.0 146986.0 131286.0 135403.0 158198.0 117827.0 141206.0 True False 164251.83965976757 137897.81425371207 168936.6833153335 147920.49914749284 126579.53106304337 123076.66566591842 147453.6046896321 133752.13412839177 124055.09467141195 136262.42091976127 1.2054082009631109 1.0120017927386877 1.2397892403130912 1.0855560773765827 0.9289393965602614 0.9032326362261879 1.0821296414252086 0.9815775562005633 0.910413111950083 1.0 17.056028218327057 -6.090620779890653 4.831442156320181 0.9702521084082755 1.1420174934251768 0.5656091333903169 0.073539017439966 0.17155423049159294 6.695239076521035 0.02167561747906278 0.028686296908213182 8.11669487409532e-07 6.090620779890653 0.1717653850169013 LENS(ph)PLGEALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LENSPLGEALR 11 0 D6RI08;D6RDK1;D6RIV2;D6R9T5;D6RG39;D6RIT9;D6RDK6;D6RBN5;Q9NX40-3;Q9NX40-2;Q9NX40-4;Q9NX40 D6RI08 OCIAD1 OCIA domain-containing protein 1 1 LENS(1)PLGEALR;LENS(1)PLGEALR;LENS(1)PLGEALR 141.59 0.00013254 42961700.0 92684.5 97717.7 98290.0 105022.2 120371.8 106439.8 109878.6 91065.1 90318.2 82162.5 True False 108374.15524768141 107418.46746221886 100633.60636690083 99138.14662056656 96785.80988619625 100857.909511441 99470.10355582538 88674.73761644909 91638.93280975254 97057.91085200809 1.116592705286312 1.1067461324817545 1.0368408456714557 1.0214329337021315 0.9971965091415708 1.0391518694980677 1.0248531282266662 0.9136270999244822 0.9441675800077926 1.0 16.566558186324905 -4.408242354475528 0.3710126120627205 0.9606333907361398 1.3018432589863196 0.6975454267810395 0.03277530927813056 4.839906173670331 0.42909099907688164 0.03134822944802342 0.7790952249068902 3.9062285107908676e-05 4.408242354475528 0.34120986825017974 LENS(ph)PLGEALR ddPTM_PC-9_Lapatinib_30min_R1 4 LENSPLGEALR 11 0 D6RI08;D6RDK1;D6RIV2;D6R9T5;D6RG39;D6RIT9;D6RDK6;D6RBN5;Q9NX40-3;Q9NX40-2;Q9NX40-4;Q9NX40 D6RI08 OCIAD1 OCIA domain-containing protein 1 1 LENS(1)PLGEALR;LENS(1)PLGEALR;LENS(1)PLGEALR;LENS(1)PLGEALR 153.7 0.00011812 55257200.0 230485.0 184096.0 177601.0 158807.0 174542.0 151870.0 132281.0 135196.0 188434.0 111418.0 True False 227198.2416342278 183669.73702282493 162999.33133968554 170486.19654462222 164275.78272277513 145374.8741262614 139129.86292409603 141477.69971726317 167210.578622012 130676.45284484726 1.738631839846321 1.4055304764118204 1.2473504429540598 1.3046435898213524 1.2571184719700075 1.1124794939059575 1.0646896200135272 1.0826564131277752 1.2795769626570892 1.0 16.995639673531095 -1.5228787452804278 0.49076319806776575 1.1135206540132583 19.17176689721591 0.8368438606134685 0.08185053537066701 40.49194610431117 0.4411789847349695 0.0471755207569431 750.270938383383 0.029999999999993768 1.5228787452804278 18.058246243202653 LENSALLTVEPS(ph)PQDKNK ddPTM_PC-9_AZD4547_30min_R2 1 LENSALLTVEPSPQDKNK 18 1 O75509 O75509 TNFRSF21 Tumor necrosis factor receptor superfamily member 21 1 LENSALLT(0.003)VEPS(0.997)PQDKNK 109.56 0.00011609 6740300.0 58026.0 73639.0 77680.0 73416.0 77267.0 59288.0 77205.0 77498.0 69939.0 62128.0 True False 76477.06098422191 97441.36666086873 76649.91244478968 56491.07546589298 66539.81077550372 55580.71198757646 84076.09543409696 65522.46482687581 73635.83275670162 59952.91763029143 1.2756186688999702 1.6252981591614173 1.2785017889781902 0.9422573195562156 1.1098677663334309 0.9270726794369405 1.4023687045985767 1.0928986847801108 1.2282276771046894 1.0 15.871542344170242 -5.522380060536725 19.63974110213083 1.110039826548633 1.4508192008296215 0.45900697198646023 0.1531643668397747 0.9208042880266818 36217.30026903791 0.040237123093665436 0.07138789501198257 3.00344677069297e-06 5.522380060536725 0.34077937428098837 LENVSQLS(ph)LDKSPTEK ddPTM_PC-9_AZD4547_30min_R2 1 LENVSQLSLDKSPTEK 16 1 Q86W56;Q86W56-3;Q86W56-2 Q86W56 PARG Poly(ADP-ribose) glycohydrolase 1 LENVS(0.048)QLS(0.525)LDKS(0.293)PT(0.134)EK 55.536 0.030758999999999998 77751000.0 43036.0 33068.0 33486.0 40104.0 37322.0 45623.0 38601.0 41962.0 39580.0 37378.0 True False 56720.55279559119 43756.58432001525 33041.9537606363 30858.642400623485 32140.48452461395 42770.18659778034 42036.4142199544 35477.73709083284 41672.11799582853 36069.40759697776 1.5725390732600715 1.213121790325206 0.9160658841373616 0.8555350491314727 0.8910732575299347 1.1857745787142906 1.165431234403656 0.9835963342465736 1.1553313672753587 1.0 15.138488108083283 -4.859087062858366 2.9470933695525896 1.0202272613948276 1.618720372568754 0.6949391356170951 0.11200131073755838 0.20202271271885366 2.801443999629907 0.03195255296723163 0.26527691984867074 1.3832890437176891e-05 4.859087062858366 0.5984931111739265 LENVSQLS(ph)LDKSPTEK ddPTM_PC-9_Lapatinib_30min_R1 1 LENVSQLSLDKSPTEK 16 1 Q86W56;Q86W56-3;Q86W56-2 Q86W56 PARG Poly(ADP-ribose) glycohydrolase 1 LENVSQLS(0.72)LDKS(0.251)PT(0.028)EK 96.096 0.01145 8297600.0 20440.0 22962.0 18092.0 19690.0 24525.0 20099.0 21361.0 20907.0 17275.0 16113.0 True False 20148.521851763064 22908.832899781086 16604.545597139597 21138.068283914494 23082.487718005184 19239.412623057386 22466.968059824274 21878.415544755917 15329.307586185409 18898.110580777076 1.0661659410680924 1.2122287464591126 0.8786352226147695 1.118528129760013 1.2214177506974906 1.018060114571849 1.1888473169734437 1.1577038588720276 0.811155566090199 1.0 14.205954381614683 -8.253646741110874 24.772326536747176 0.90557777820557 1.107415953864887 0.3662098792319024 0.1063594534180893 485.68900970769187 1543989.5167113356 0.07307367867204766 0.026485180184824795 5.57639153017325e-09 8.253646741110874 0.20183817565931694 LENVSQLSLDKS(ph)PTEK ddPTM_PC-9_AZD4547_30min_R2 1 LENVSQLSLDKSPTEK 16 1 Q86W56;Q86W56-3;Q86W56-2 Q86W56 PARG Poly(ADP-ribose) glycohydrolase 1 LENVSQLS(0.028)LDKS(0.805)PT(0.166)EK 70.538 0.0092381 103990000.0 119780.0 98122.0 99434.0 81025.0 96749.0 113990.0 114690.0 110910.0 112080.0 117310.0 True False 157867.54842122665 129838.01761970899 98115.44019097848 62345.93807377114 83317.07135930215 106862.18728012124 124897.18781603007 93771.40795825429 118004.31998414506 113203.01260638505 1.3945525369553846 1.1469484303493322 0.8667211051364231 0.5507445132273326 0.7359969442597923 0.94398713267189 1.1033026855063168 0.8283472833386879 1.04241324737933 1.0 16.78855282672727 -5.015602057559743 2.746683953670233 0.8713292556781477 1.3924755918698843 0.5374394458809162 0.1515692332626201 0.24774210870934493 3.400654401049294 0.04396446983074537 0.23004114803230977 9.647125813603772e-06 5.015602057559743 0.5211463361917367 LENVSQLSLDKS(ph)PTEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LENVSQLSLDKSPTEK 16 1 Q86W56;Q86W56-3;Q86W56-2 Q86W56 PARG Poly(ADP-ribose) glycohydrolase 1 LENVS(0.003)QLS(0.018)LDKS(0.715)PT(0.265)EK 55.782 0.030293 54081000.0 55390.0 52939.0 41535.0 60195.0 55419.0 41243.0 56788.0 55435.0 44875.0 37858.0 True False 64766.43299763264 58194.434058337436 42525.351922364694 56822.46930482312 44560.04477862023 39080.144475847985 51408.62953048381 53979.88998823761 45531.211979840766 44721.35571623688 1.4482215925783761 1.3012672162174395 0.9508958581710686 1.2705891490716306 0.9963929774705357 0.8738586710970223 1.1495320011468033 1.2070271377895474 1.0181089381266197 1.0 15.448676303317436 -5.0582278327103305 4.134473057846269 1.0683350567214835 1.4254108197164708 0.5601214947711411 0.11505276578945683 0.15275822541471484 5.204921848251779 0.030251346148748356 0.10116834853583352 8.745248754427316e-06 5.0582278327103305 0.3570757629949872 LENVSQLSLDKS(ph)PTEK ddPTM_PC-9_Lapatinib_30min_R1 1 LENVSQLSLDKSPTEK 16 1 Q86W56;Q86W56-3;Q86W56-2 Q86W56 PARG Poly(ADP-ribose) glycohydrolase 1 LENVS(0.006)QLS(0.061)LDKS(0.466)PT(0.466)EK 58.163999999999994 0.025775 50008000.0 65379.0 59956.0 51158.0 53928.0 52294.0 56438.0 53158.0 48842.0 56753.0 47418.0 True False 64446.68347095981 59817.175565685655 46951.986715590734 57894.04501853434 49218.169733959716 54024.278303403786 55910.261135908375 51111.377626487214 50360.87950441565 55614.13811948659 1.1588183445816702 1.0755749812605002 0.8442455156765123 1.0409950954224876 0.8849938414619466 0.9714126682559208 1.0053245995790776 0.9190356868729095 0.9055409506880364 1.0 15.763164068289754 -5.046383503204926 5.618724786142935 0.9478045327978949 1.1415027013880918 0.6012850084022757 0.05740844216408631 0.10640123277782063 8.325116637568023 0.013805669402407178 0.040899611922687554 8.987036319032524e-06 5.046383503204926 0.19369816859019695 LENVSQLSLDKSPT(ph)EK ddPTM_PC-9_AZD4547_30min_R2 1 LENVSQLSLDKSPTEK 16 1 Q86W56;Q86W56-3;Q86W56-2 Q86W56 PARG Poly(ADP-ribose) glycohydrolase 1 LENVSQLS(0.084)LDKS(0.416)PT(0.5)EK 113.95 0.0020751 9046400.0 32038.0 34498.0 33554.0 35574.0 34282.0 36115.0 34155.0 29881.0 32929.0 36915.0 True False 42225.41756820222 45648.803854841164 33109.05203620585 27372.963912821153 29522.536050394265 33856.723340833276 37194.72883299765 25263.578047070583 34669.55971411414 35622.61708605152 1.1853541660400944 1.281455647814139 0.9294390683375735 0.7684152976940983 0.8287582009788433 0.95042773693599 1.0441324045099907 0.7092005055676511 0.9732457228048368 1.0 15.120505890328443 -5.310446022909716 5.647341178015303 0.8879400382424667 1.2336752196998275 0.6306238504643906 0.10175833697229827 0.11028816432686879 8.493941887429727 0.026614076358738963 0.05812008611871072 4.892760719341542e-06 5.310446022909716 0.3457351814573608 LEPAS(ph)PPEDTSAEVSR ddPTM_PC-9_AZD4547_30min_R2 1 LEPASPPEDTSAEVSR 16 0 E9PFE2;Q9UHL9-2;Q9UHL9;Q9UHL9-3 E9PFE2 GTF2IRD1 General transcription factor II-I repeat domain-containing protein 1 1 LEPAS(1)PPEDTSAEVSR 132.4 6.7241e-06 8422600.0 7182.0 11163.0 11777.0 13312.0 9396.0 11527.0 14313.0 17297.0 12508.0 12897.0 True False 9465.726605119811 14771.221445637193 11620.829285044902 10243.124068349793 8091.527586765787 10806.214867777522 15586.829272044968 14624.146095518223 13169.14734441191 12445.479955541286 0.7605754570280951 1.1868743912170605 0.9337389418935818 0.8230396983435817 0.6501579381165671 0.8682843013190592 1.2524088526698411 1.1750568196453441 1.0581470052947548 1.0 13.603334247966224 -7.245571239227707 24.4472488149962 1.135991232390571 0.8755373935757306 0.4206727107953302 0.14379549460973995 621.995974664171 958279.3335688625 0.058889844639549625 0.045444738109278154 5.6810519513081394e-08 7.245571239227707 -0.2604538388148404 LEPAS(ph)PPEDTSAEVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LEPASPPEDTSAEVSR 16 0 E9PFE2;Q9UHL9-2;Q9UHL9;Q9UHL9-3 E9PFE2 GTF2IRD1 General transcription factor II-I repeat domain-containing protein 1 1 LEPAS(1)PPEDTSAEVSR;LEPAS(0.991)PPEDT(0.007)S(0.002)AEVSR 213.94 6.4733e-22 13238600.0 71504.0 105225.0 116735.0 88456.0 98607.0 80008.0 99253.0 75168.0 77438.0 67059.0 True False 83608.21493162547 115671.04259220154 119518.40511995276 83500.09709822148 79285.6662062722 75812.23963396568 89851.03731050776 73194.91964707946 78570.38425169703 79216.26586124807 1.055442515784197 1.4601930718977103 1.5087609068735484 1.0540776719326406 1.0008760870544653 0.9570286961866551 1.134249845453295 0.9239885123502872 0.991846603692702 1.0 16.27350907586355 -5.868389742655794 6.531474224624777 1.0046645392510414 1.3516767063614339 0.608017841420629 0.12273302044574044 0.13562392319352587 7.358989258229079 0.03460543900650854 0.05182684700735952 1.3539737897326343e-06 5.868389742655794 0.3470121671103925 LEPAS(ph)PPEDTSAEVSR ddPTM_PC-9_Lapatinib_30min_R1 3 LEPASPPEDTSAEVSR 16 0 E9PFE2;Q9UHL9-2;Q9UHL9;Q9UHL9-3 E9PFE2 GTF2IRD1 General transcription factor II-I repeat domain-containing protein 1 1 LEPAS(0.999)PPEDTS(0.001)AEVSR;LEPAS(0.984)PPEDT(0.004)S(0.012)AEVSR;LEPAS(1)PPEDTSAEVSR 203.53 7.7459e-17 19069100.0 43384.4 48516.3 51105.8 41371.9 49818.2 54130.9 42880.8 51779.1 51995.9 40531.9 True False 42765.73050027542 48403.96348818256 46904.07839809291 44414.52753861257 46887.99142234966 51815.847592291 45100.95800663417 54184.94601489794 46139.57420089945 47537.78490963811 0.8996155496425924 1.018220844328168 0.986669414387949 0.93429947615434 0.986331010405226 1.0899928907243956 0.9487391575430794 1.1398290037681613 0.970587381986846 1.0 15.536787059978868 -6.53729954200049 24.399771655415613 1.0340187645880323 0.9651210322657595 0.23523964042295276 0.05941985940797801 251.88460812134824 426181.3479069041 0.01831141264562167 0.01831983707972599 2.9020203797995197e-07 6.53729954200049 -0.06889773232227281 LEPASPPEDTS(ph)AEVSR ddPTM_PC-9_AZD4547_30min_R2 1 LEPASPPEDTSAEVSR 16 0 E9PFE2;Q9UHL9-2;Q9UHL9;Q9UHL9-3 E9PFE2 GTF2IRD1 General transcription factor II-I repeat domain-containing protein 1 1 LEPAS(0.006)PPEDT(0.014)S(0.98)AEVSR 164.63 5.8633999999999995e-05 10356000.0 11917.0 11454.0 14601.0 17900.0 18223.0 18735.0 13909.0 19268.0 14660.0 13866.0 True False 15706.358111001493 15156.28150482203 14407.381199876083 13773.431552243186 15693.051001876636 17563.497488315406 15146.874054696656 16290.573334592425 15434.897671016832 13380.555560481933 1.1738195802114955 1.1327094332005554 1.0767401349482657 1.029361709981727 1.1728250692538071 1.312613471759525 1.1320063644764766 1.2174810874598454 1.1535318994229344 1.0 13.707850397450553 -3.8971747982669593 3.8451423701162706 1.1447220991222176 8.673342114023646 0.008394377318543977 0.08575553359038622 7717.402704563123 419.0440451670995 0.02262030540229778 507904.1094877181 0.0001267141754004791 3.8971747982669593 7.528620014901428 LEPNS(ph)PMHGGTLLEDVVGGR ddPTM_PC-9_AZD4547_30min_R2 3 LEPNSPMHGGTLLEDVVGGR 20 0 Q5VY60;Q7Z4H7-3;Q7Z4H7 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 LEPNS(1)PMHGGTLLEDVVGGR;LEPNS(1)PMHGGTLLEDVVGGR;LEPNS(0.999)PMHGGT(0.001)LLEDVVGGR 101.23 0.00019408 14140500.0 18568.9 18580.2 24789.8 27526.4 25473.9 26165.0 23871.8 31317.4 21747.3 27499.5 True False 24473.42394288628 24585.886294385735 24461.071054632423 21180.613758640604 21937.288696521166 24528.8984137589 25996.343954195694 26478.015432258926 22896.81788000711 26536.750875196365 0.9222464369502501 0.9264844219254407 0.9217809357925555 0.7981615329719175 0.8266757599561946 0.9243369140826436 0.9796355279686564 0.9977866377382192 0.8628342628565179 1.0 14.695704119391122 -6.9950331147057945 23.751614372242592 0.9587520357569413 0.8791743240735592 0.3427496276833857 0.05299941632044064 92.33445764519776 441535.60051847796 0.01993370577390412 0.01750861963031717 1.0115023248457885e-07 6.9950331147057945 -0.07957771168338212 LEPNS(ph)PMHGGTLLEDVVGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LEPNSPMHGGTLLEDVVGGR 20 0 Q5VY60;Q7Z4H7-3;Q7Z4H7 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 LEPNS(1)PMHGGTLLEDVVGGR;LEPNS(1)PMHGGTLLEDVVGGR 82.859 0.00069105 9031900.0 20867.9 21868.2 20169.3 19234.6 30972.0 28128.0 35142.0 29567.0 29984.0 25426.2 True False 24400.423310187747 24039.13037410103 20650.21260449619 18156.94772141457 24903.25893436231 26652.91816348598 31813.095353952645 28790.897578826032 30422.45927584502 30035.76878631153 0.8123788501564165 0.8003500940870406 0.6875206941234445 0.6045108367490629 0.8291200771831648 0.8873725974223358 1.0591736665801978 0.9585537092011164 1.0128743330089063 1.0 14.874393970665526 -6.816895824523404 2.2279968937075623 1.0021479218133273 0.7298846333469468 0.7925542485342215 0.0635426297565008 0.142786693623877 1.4535962129256335 0.02694286807329988 0.023964654012811355 1.524418376600031e-07 6.816895824523404 -0.2722632884663806 LEPNS(ph)PMHGGTLLEDVVGGR ddPTM_PC-9_Lapatinib_30min_R1 3 LEPNSPMHGGTLLEDVVGGR 20 0 Q5VY60;Q7Z4H7-3;Q7Z4H7 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 LEPNS(1)PMHGGTLLEDVVGGR;LEPNS(1)PMHGGTLLEDVVGGR;LEPNS(1)PMHGGTLLEDVVGGR 96.561 0.00043232 7332200.0 10514.3 12613.1 13385.8 10306.300000000001 13564.599999999999 18638.1 18058.3 18019.0 18981.899999999998 15013.6 True False 10364.364153913531 12583.895141896548 12285.27119468225 11064.25968280894 12766.756897029676 17840.991910533154 18993.270414059487 18856.228521593588 16843.958533731548 17608.680755635494 0.588594017788443 0.7146415632454004 0.6976826580691153 0.6283412049064452 0.7250263136801883 1.0131929903279842 1.0786310841589235 1.0708484515831107 0.9565712938682698 1.0 14.103999205890796 -6.729618427961741 3.865665650306575 1.035481656189104 0.6656921736439894 0.9358173515661664 0.046443514400623574 0.0499768207007021 1.5937333168565133 0.01622481248521706 0.015490529815479269 1.8637238892295058e-07 6.729618427961741 -0.3697894825451147 LEPQELS(ph)PLSATVFPK ddPTM_PC-9_AZD4547_30min_R2 1 LEPQELSPLSATVFPK 16 0 A0A087WUE6;Q3T8J9-2;Q3T8J9-3;Q3T8J9;Q9H869-7;Q9H869-5;Q9H869-6;Q9H869-4;Q9H869-3;Q9H869-2;Q9H869;Q9H869-8;Q9H869-9 A0A087WUE6;Q9H869-7 GON4L;YY1AP1 GON-4-like protein;YY1-associated protein 1 1 LEPQELS(0.971)PLS(0.029)ATVFPK 152.59 3.1416e-05 13900000.0 69759.0 62534.0 74679.0 87163.0 88532.0 77959.0 63302.0 87835.0 64244.0 81891.0 True False 91940.91092266137 82746.89258097975 73688.70766560826 67068.91700492581 76240.8599735577 73084.2114060091 68935.75536777676 74262.1189975049 67639.80668327455 79024.02101568056 1.163455234762323 1.0471106318996406 0.9324849168455549 0.8487155695559643 0.9647808222569363 0.9248353913996248 0.8723392518092441 0.9397410818005483 0.8559398245484489 1.0 16.270003637049406 -5.010506799448303 2.108092879740714 0.9117738680616585 1.1784818315815915 0.7547108620637869 0.04529737462070928 0.19383120147533284 1.362674791422136 0.011739368036490493 0.08276419918733935 9.760975002271853e-06 5.010506799448303 0.266707963519933 LEPQELS(ph)PLSATVFPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LEPQELSPLSATVFPK 16 0 A0A087WUE6;Q3T8J9-2;Q3T8J9-3;Q3T8J9;Q9H869-7;Q9H869-5;Q9H869-6;Q9H869-4;Q9H869-3;Q9H869-2;Q9H869;Q9H869-8;Q9H869-9 A0A087WUE6;Q9H869-7 GON4L;YY1AP1 GON-4-like protein;YY1-associated protein 1 1 LEPQELS(0.898)PLS(0.102)ATVFPK;LEPQELS(0.618)PLS(0.38)AT(0.002)VFPK 163.18 4.5177e-05 53852000.0 85985.0 91164.0 97517.0 106176.0 117161.0 105331.0 110513.0 100257.0 89680.0 79245.0 True False 100540.5622188383 100214.1594381131 99842.17511528212 100227.30294723636 94204.14309727572 99807.25693537192 100044.40859516725 97625.3599810724 90991.40034210843 93611.49119692498 1.0740194492504882 1.0705326681240284 1.0665589644891995 1.070673072992653 1.0063309738235449 1.0661859528058715 1.0687193133662374 1.0428779494143905 0.9720110125229731 1.0 16.514398016999678 -8.140635697247363 4.315338109131667 0.9866838237634884 1.0593704634017294 0.6859807091731492 0.01978602176293214 0.13287529236870754 3.9142269822912272 0.015234730451690175 0.005299027559874533 7.23376344801332e-09 8.140635697247363 0.07268663963824096 LEPQELS(ph)PLSATVFPK ddPTM_PC-9_Lapatinib_30min_R1 2 LEPQELSPLSATVFPK 16 0 A0A087WUE6;Q3T8J9-2;Q3T8J9-3;Q3T8J9;Q9H869-7;Q9H869-5;Q9H869-6;Q9H869-4;Q9H869-3;Q9H869-2;Q9H869;Q9H869-8;Q9H869-9 A0A087WUE6;Q9H869-7 GON4L;YY1AP1 GON-4-like protein;YY1-associated protein 1 1 LEPQELS(0.998)PLS(0.001)ATVFPK;LEPQELS(0.993)PLS(0.007)ATVFPK 139.88 1.0155e-05 26306000.0 73303.0 59274.0 70245.0 58603.0 69652.0 66640.0 64515.0 57426.0 68097.0 53080.0 True False 72257.6857778763 59136.7546947837 64469.72725354137 62912.86011387713 65555.20630110077 63789.962545427275 67855.27102568057 60094.22160391989 60427.198766799855 62254.807275345855 1.1606764030011185 0.9499146697736712 1.0355782962815896 1.010570313640532 1.0530143641945213 1.0246592245204713 1.0899603419470003 0.9652944765876482 0.9706430942680025 1.0 15.92589762499555 -4.744732408367855 24.949431724927102 1.014936921699386 1.160676838518384 0.5481280290476759 0.040614517704175054 792.9563423421395 1184100.037969413 0.010252025548464763 0.27892076230804524 1.7999796354813884e-05 4.744732408367855 0.14573991681899812 LEPQELSPLS(ph)ATVFPK ddPTM_PC-9_AZD4547_30min_R2 1 LEPQELSPLSATVFPK 16 0 A0A087WUE6;Q3T8J9-2;Q3T8J9-3;Q3T8J9;Q9H869-7;Q9H869-5;Q9H869-6;Q9H869-4;Q9H869-3;Q9H869-2;Q9H869;Q9H869-8;Q9H869-9 A0A087WUE6;Q9H869-7 GON4L;YY1AP1 GON-4-like protein;YY1-associated protein 1 1 LEPQELS(0.198)PLS(0.795)AT(0.007)VFPK 156.0 4.0528e-05 19077000.0 43824.0 51689.0 55805.0 88739.0 69274.0 71401.0 47484.0 69308.0 49935.0 66281.0 True False 57759.12040417298 68396.45841651353 55064.98923766073 68281.59455388316 59656.50085628064 66936.28418271728 51709.98401130324 58598.04113939863 52574.462155677065 63960.52236436634 0.9030432877820228 1.069354281174829 0.8609215059872387 1.0675584255691473 0.9327081557657266 1.046524976788007 0.8084671935092245 0.9161595148579453 0.8219830015798515 1.0 15.964894100878693 -7.259656724030165 24.994959102661177 0.8796657219047778 0.9804942836968938 0.23726166529105963 0.08162402006237443 210.29014997225735 2948541.1270162845 0.029524937228714028 0.021660168978742164 5.499754148389495e-08 7.259656724030165 0.10082856179211608 LEPSTST(ph)DQPVTPEPTSQATR ddPTM_PC-9_Lapatinib_30min_R1 1 LEPSTSTDQPVTPEPTSQATR 21 0 Q14676;Q14676-3;Q14676-2 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 LEPS(0.004)T(0.018)S(0.119)T(0.816)DQPVT(0.044)PEPTSQATR 159.4 1.7987e-05 15992000.0 23852.0 24029.0 28448.0 21059.0 22279.0 21579.0 21826.0 18086.0 26048.0 18389.0 True False 23511.866106078913 23973.362326837356 26109.115252455627 22607.749110764613 20968.593022199286 20656.116473105893 22956.04348456181 18926.341586189094 23114.19994239985 21567.51414819771 1.090151880486592 1.1115496279315384 1.210576011359076 1.048231565094572 0.9722304053270564 0.9577421083937029 1.0643805923493568 0.8775393147369592 1.071713679359352 1.0 14.39657228192923 -5.97797030579402 5.896139104731562 0.9882476843573685 1.1350576190057584 0.5540576025729438 0.058882772930382014 0.11804003091096144 13.445652348729055 0.01609279858267776 0.02349935856406466 1.0520338025300947e-06 5.97797030579402 0.14680993464838987 LEPSTSTDQPVT(ph)PEPTSQATR ddPTM_PC-9_AZD4547_30min_R2 3 LEPSTSTDQPVTPEPTSQATR 21 0 Q14676;Q14676-3;Q14676-2 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 LEPSTSTDQPVT(0.999)PEPTSQATR;LEPSTS(0.002)T(0.02)DQPVT(0.964)PEPT(0.004)S(0.01)QATR;LEPST(0.001)S(0.064)T(0.401)DQPVT(0.53)PEPT(0.002)S(0.002)QATR 265.09 3.298399999999999e-86 34481000.0 45426.1 43413.1 60938.4 84597.0 56480.2 51445.6 42325.2 56021.8 49350.9 47086.5 True False 59870.654878422836 57445.53558555872 60130.31699955679 65094.468660621045 48638.89914921764 48228.69849932634 46092.06080522303 47364.918062895464 51959.4878221408 45438.01596701517 1.3176335630914158 1.2642615299765767 1.3233482078796575 1.4325992734338375 1.0704450472601201 1.061417350051926 1.0143942208806531 1.0424072674581366 1.1435245733409611 1.0 15.471612221059319 -6.279328048144851 22.614925026921192 1.0557391128587224 1.3286526440386113 0.869452722500379 0.05296173882435794 81.60503578451224 103164.95636394512 0.016807416896908563 0.019114536313372763 5.256200846625914e-07 6.279328048144851 0.2729135311798889 LEPSTSTDQPVT(ph)PEPTSQATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LEPSTSTDQPVTPEPTSQATR 21 0 Q14676;Q14676-3;Q14676-2 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 LEPSTSTDQPVT(0.999)PEPTSQATR;LEPSTST(0.003)DQPVT(0.996)PEPTSQATR;LEPSTSTDQPVT(0.962)PEPT(0.028)S(0.004)QAT(0.007)R 162.32 1.0253000000000001e-23 22897000.0 66366.3 56753.1 61378.3 75528.8 80815.7 66781.7 66631.1 59168.4 60239.3 39992.3 True False 77600.80379582586 62387.1726998287 62841.791450499026 71297.16620367329 64980.44372535667 63279.55008953608 60319.31984061104 57615.29219410191 61120.18580094092 47242.587411127395 1.6426027457071068 1.3205706147486365 1.330193685278496 1.5091714935765805 1.3754632691868893 1.3394598720609316 1.2767996662774568 1.2195625885751413 1.2937518698763064 1.0 15.527800360859011 -11.769437620129866 0.06515209136954586 2.2893794836737874e-12 1.9833914180222982 0.7178419110694387 0.08520572789333228 104.10852950536338 0.8836916396357702 22.871521868688358 7.385825758338034 1.7004441793323711e-12 11.769437620129866 1.983391418020009 LEPSTSTDQPVT(ph)PEPTSQATR ddPTM_PC-9_Lapatinib_30min_R1 2 LEPSTSTDQPVTPEPTSQATR 21 0 Q14676;Q14676-3;Q14676-2 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 LEPSTSTDQPVT(0.998)PEPT(0.002)SQATR;LEPSTSTDQPVT(0.998)PEPT(0.001)SQATR 189.11 6.4231000000000006e-15 19813700.0 49836.9 49899.9 52159.8 37166.0 38816.0 41848.8 47565.4 37226.6 46507.8 29623.7 True False 49126.21666703185 49784.35984739071 47871.422586650566 39899.31162214147 36532.91919519218 40059.024378317525 50028.103672710335 38956.2837383848 41269.60181515448 34744.11707390096 1.4139434472472006 1.4328860261867946 1.3778281510169834 1.1483760412525486 1.051485036084999 1.1529728700001707 1.4399014246440696 1.1212339532337097 1.1878155293851265 1.0 15.084481098772445 -1.5228787578016563 0.33235994546980135 1.135308352340464 4.747585901039033 0.42841280853005426 0.11997202169379476 63.05703674819147 0.896837668753972 0.11627965689179488 140.2548504689506 0.029999999135057957 1.5228787578016563 3.612277548698569 LEPTAPALS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 LEPTAPALSPR 11 0 Q96IF1 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 LEPTAPALS(1)PR;LEPTAPALS(1)PR;LEPTAPALS(1)PR;LEPTAPALS(1)PR 122.18 0.00069485 152033000.0 169918.0 144907.0 264004.0 336463.0 288616.0 230630.0 210081.0 272597.0 209314.0 249733.0 True False 223948.38948604095 191745.35393916946 260503.1344628508 258896.6536515306 248546.65027479667 216208.6696413231 228777.8020191773 230473.39730589002 220377.91071699993 240989.923682809 0.9292852832336753 0.7956571420452614 1.0809710650214783 1.0743048908231136 1.0313570230510294 0.897168920331694 0.9493251772646507 0.9563611365313314 0.9144693991731431 1.0 17.87861329990968 -5.253538803125023 24.999795593369843 0.9864425000620559 0.8624712170614177 0.36824058307528207 0.06573986982396857 687.3946929206961 2175110.668920721 0.018220906097774457 0.046369980417281784 5.577777638675537e-06 5.253538803125023 -0.1239712830006382 LEPTAPALS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LEPTAPALSPR 11 0 Q96IF1 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 LEPT(0.001)APALS(0.999)PR;LEPTAPALS(1)PR;LEPTAPALS(1)PR;LEPTAPALS(1)PR 129.74 0.00024419999999999997 87903700.0 118869.0 126996.0 139223.0 143692.0 160678.0 144963.0 152203.0 168943.5 151762.0 117744.1 True False 138991.17393023308 139603.32359267477 142542.60432616778 135641.40309574959 129194.29933667392 137360.88508722323 137785.2299857053 164508.91213543504 153981.23214450316 139090.17326821748 0.9992882362883143 1.003689335575618 1.0248215310746125 0.9752047891563311 0.9288528175713705 0.9875671433835981 0.9906180051987153 1.1827500697565514 1.107060466792073 1.0 17.08566097139819 -7.707664998216202 12.37291387949101 1.108635453403703 0.9864967501952339 0.5213925379284102 0.04763734244002037 0.5845477840797387 133.438479211606 0.022053089257585617 0.012720320618081421 1.960356250661889e-08 7.707664998216202 -0.1221387032084692 LEPTAPALS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 LEPTAPALSPR 11 0 Q96IF1 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 LEPTAPALS(1)PR;LEPTAPALS(1)PR;LEPTAPALS(1)PR 152.96 0.00040282 128254000.0 202238.0 179063.0 213620.0 157750.0 196223.0 207141.0 173488.0 175992.0 212279.0 156196.0 True False 199354.0490340925 178648.39062509776 196056.9881970465 169351.46123857328 184681.54892926101 198282.0622992553 182470.35975669653 184169.2308103835 188369.90362303058 183194.2704819126 1.0882111569847126 0.9751854692570002 1.0702135371444594 0.9244364509494523 1.0081185860422162 1.0823595180004955 0.9960483986572739 1.0053220022979221 1.0282521561809925 1.0 17.483014857366257 -6.877660783175671 0.0026622362501448004 0.0004966535889184604 2.032078560726068 0.024436260949168065 0.04793606367565889 209104.6245163012 238.00304129252245 90217.16524227311 91399.03204539564 1.3253763501395798e-07 6.877660783175671 2.0315819071371495 LEPTNVQTVTCS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 LEPTNVQTVTCSPR 14 0 J3KTI7;J3QR52;J3QLN7;Q99741 J3KTI7 CDC6 Cell division control protein 6 homolog 1 LEPTNVQT(0.002)VT(0.223)CS(0.775)PR;LEPTNVQTVT(0.01)CS(0.99)PR 113.65 0.00018834 14800800.0 37016.0 24235.0 45764.0 52448.0 51006.0 36967.0 42213.0 46967.0 37202.0 47745.0 True False 48786.31801936994 32068.48980874472 45157.13945833358 40356.923913522354 43924.69732764745 34655.44764614659 45969.87522258323 39709.329344291174 39168.42177061173 46073.46208244697 1.0588810958479395 0.6960295224040077 0.9801117045974609 0.8759255781843558 0.9533622033665634 0.7521780669343187 0.997751702277585 0.8618698823464279 0.8501297710278665 1.0 15.491648389506205 -10.607166917279049 5.544506098472029 1.0000006313993268 0.8881160954404381 0.08537465722071669 0.10562089317206808 1.1102226070496003e-06 1.833904934264507e-07 0.09283860233605022 0.022516479883680583 2.4707743420329228e-11 10.607166917279049 -0.1118845359588887 LEPTNVQTVTCS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LEPTNVQTVTCSPR 14 0 J3KTI7;J3QR52;J3QLN7;Q99741 J3KTI7 CDC6 Cell division control protein 6 homolog 1 LEPTNVQTVT(0.204)CS(0.795)PR;LEPTNVQTVT(0.001)CS(0.999)PR 124.04 3.9345e-05 11963800.0 22257.6 27351.0 26895.8 37639.0 28840.0 28988.0 29865.0 33555.0 29403.0 19965.2 True False 26025.3720723616 30066.226523538186 27537.09787488952 35530.20885728442 23189.00902967225 27467.81824954249 27035.97099612418 32674.216804461317 29832.963249989032 23584.732715563772 1.1034838675609508 1.2748173526553142 1.167581511607191 1.506491902443216 0.9832211926815527 1.1646440339523643 1.1463335761394025 1.3853969514311821 1.2649269173316515 1.0 14.525565630528654 -6.2913016850351005 24.997000157443725 1.1764971864455598 1.2571090149410529 0.10213862710492427 0.14667564851251608 2212.8822239084743 1852342.9450686104 0.04615816528710442 0.052346200877515 5.113265163835973e-07 6.2913016850351005 0.08061182849549309 LEPTNVQTVTCS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 LEPTNVQTVTCSPR 14 0 J3KTI7;J3QR52;J3QLN7;Q99741 J3KTI7 CDC6 Cell division control protein 6 homolog 1 LEPTNVQTVT(0.072)CS(0.928)PR;LEPTNVQTVT(0.001)CS(0.999)PR 180.56 4.3923999999999995e-05 16651100.0 38297.0 48486.0 47160.0 50442.0 51029.0 38936.0 37289.0 38679.0 43884.0 36138.0 True False 37750.87775719033 48373.73364597096 43282.68684286448 54151.672949579224 48027.57454687402 37270.7980442491 39219.64196352171 40476.16754463165 38941.32180099336 42384.405149141814 0.8906784847953609 1.1413097217184944 1.0211936841053166 1.2776320148656297 1.1331425881258703 0.8793516840238997 0.9253318956704956 0.9549778368294783 0.9187653256891782 1.0 15.371245919042142 -6.757007790375455 24.997539910768737 0.9322243659607928 1.1017780667321586 0.3979195497600233 0.09626184690633408 111.34356074948911 628062.3874666382 0.032555258082529105 0.03149520278385962 1.7498153001520973e-07 6.757007790375455 0.16955370077136578 LEPVYS(ph)PPGSPPPGDPR ddPTM_PC-9_AZD4547_30min_R2 2 LEPVYSPPGSPPPGDPR 17 0 E9PJN1;O75676-2;O75676;A0A0A6YYC0 E9PJN1 RPS6KA4 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-4 1 LEPVYS(0.824)PPGS(0.176)PPPGDPR;LEPVYS(0.996)PPGS(0.004)PPPGDPR 107.73 0.00057069 130955000.0 26619.0 30095.0 43412.0 59699.0 38313.0 48717.0 36294.0 42501.0 40597.0 42917.0 True False 35083.28829040438 39822.62021019895 42836.32851510309 45936.317890355596 32993.90128051912 45670.71828867157 39524.09568920562 35933.44702582067 42742.87453958187 41414.488892918154 0.8471259510437564 0.9615625177257369 1.034331936966825 1.1091847109143165 0.796675322151834 1.102771506048484 0.9543543031860091 0.867654001929872 1.0320753842960226 1.0 15.337847963628137 -4.7813064661367966 4.115407558340095 0.9837307399866595 0.8358163274241437 0.17065149143763847 0.09189332449391871 0.3968122399148608 13.065052006631548 0.022486418167393118 0.17285177632713658 1.6546019577795643e-05 4.7813064661367966 -0.1479144125625158 LEPVYS(ph)PPGSPPPGDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LEPVYSPPGSPPPGDPR 17 0 E9PJN1;O75676-2;O75676;A0A0A6YYC0 E9PJN1 RPS6KA4 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-4 1 LEPVYS(0.806)PPGS(0.194)PPPGDPR;LEPVYS(0.944)PPGS(0.056)PPPGDPR 151.73 4.1071e-05 66133000.0 63674.0 69042.0 74143.0 62966.0 94920.0 89593.0 98639.0 81638.0 83414.0 78224.0 True False 74452.75058117461 75896.03347731783 75910.85030889338 59438.219158526306 76321.10738892137 84894.5853605375 89295.1998354826 79495.08900261096 84633.77194621607 92405.39197915678 0.8057186814159977 0.8213377147346246 0.8214980606977572 0.6432332343975485 0.825937813305706 0.918718957219364 0.9663418759765046 0.860286259275239 0.915896465925996 1.0 16.495689416846936 -6.667359880320845 4.015506818909604 0.9260750182485222 0.7754550917455026 0.6219449717295478 0.058817717202003995 0.16211818536428363 4.886364998702108 0.020738969021439745 0.020440463834790805 2.1509985601627785e-07 6.667359880320845 -0.15061992650301959 LEPVYS(ph)PPGSPPPGDPR ddPTM_PC-9_Lapatinib_30min_R1 2 LEPVYSPPGSPPPGDPR 17 0 E9PJN1;O75676-2;O75676;A0A0A6YYC0 E9PJN1 RPS6KA4 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-4 1 LEPVYS(0.958)PPGS(0.042)PPPGDPR;LEPVY(0.001)S(0.573)PPGS(0.426)PPPGDPR 145.79 9.6816e-05 124691000.0 48037.0 38831.0 58774.0 46873.0 56150.0 70937.0 65614.0 61380.0 82755.0 51582.0 True False 47351.98357109308 38741.08920526951 53941.8285942009 50320.196783744206 52847.36739514744 67903.18987222355 69011.17186823234 64231.93887870657 73434.2604512169 60497.87997130534 0.782704841782101 0.6403710216563745 0.8916317170086947 0.8317679364568066 0.8735408153180475 1.122406105873968 1.1407204996433749 1.0617221447953602 1.2138319637985233 1.0 15.884596966424711 -6.526072194448016 1.4293319343776671 1.1218745526465008 0.7625667153273673 0.7783969430822459 0.08118614031648479 0.1799584772488096 0.7557695373570337 0.03328106666571434 0.03683189292791312 2.978021340298081e-07 6.526072194448016 -0.3593078373191335 LEQLCEEFS(ph)EEER ddPTM_PC-9_AZD4547_30min_R2 1 LEQLCEEFSEEER 13 0 Q9H3C7-3;Q9H3C7 Q9H3C7-3 GGNBP2 Gametogenetin-binding protein 2 1 LEQLCEEFS(1)EEER 114.21 0.0011251 0.0 1185.0 3438.7 2206.2 3222.0 2726.9 3784.7 2723.3 3590.4 2493.4 3051.6 True False 1561.805350468807 4550.192527556443 2176.944346494528 2479.2176794037723 2348.3170047202675 3548.0421107033553 2965.66842426885 3035.5861791841717 2625.1960336230113 2944.7644128347492 0.5303668244772594 1.5451804931234698 0.7392592551737995 0.8419069683802574 0.7974549660017396 1.2048645029935914 1.0070987041757875 1.0308417766642302 0.8914791357098382 1.0 11.523936504785665 -6.741085798829188 24.983224837387656 1.0275496954444185 0.9160474153880811 0.06246388430220684 0.2542669636327441 918.4761497062323 1127391.5040667888 0.08178366452798294 0.0816894092124146 1.8151570265506243e-07 6.741085798829188 -0.11150228005633744 LEQLFQDEVAK ddPTM_PC-9_Lapatinib_30min_R1 1 LEQLFQDEVAK 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 133.05 0.00035709 2665700.0 14211.0 12571.0 15858.0 10366.0 14974.0 13041.0 12529.0 12990.0 12444.0 14596.0 False True 14008.348534021776 12541.892621859944 14554.21645365023 11128.350219962293 14093.2587600167 12483.266830055796 13177.690315132179 13593.56282232647 11042.425678870688 17118.89915205253 0.8182972754029102 0.7326342956086747 0.8501841341769456 0.6500622569896979 0.8232573038043127 0.7292096716720871 0.769774399515181 0.7940675800229025 0.645042977401191 1.0 14.063302310322475 -11.191173718086093 4.235841454456026 1.0095057123878768 0.7584346860461448 0.5486383341741958 0.06612395891485413 0.0056002723681652196 0.0004385521413120927 0.06040442676214383 0.014216862965345916 6.4391164890073066e-12 11.191173718086093 -0.25107102634173195 LERAST(ph)KMLDRWSIMTYELK ddPTM_PC-9_AZD4547_30min_R2 1 LERASTKMLDRWSIMTYELK 20 3 A0A0D9SFR6;Q86XP1-5;Q86XP1-3;Q86XP1-2;Q86XP1 A0A0D9SFR6 DGKH Diacylglycerol kinase eta 1 LERAS(0.161)T(0.839)KMLDRWSIMTYELK 53.342 0.042875 0.0 8328.3 9665.1 11345.0 18835.0 19222.0 20122.0 15567.0 15557.0 17569.0 17883.0 True False 10976.526160598623 12789.15456366819 11194.557887308687 14492.881747849184 16553.357095871863 18863.768159054318 16952.43284272507 13153.02311429595 18497.66147217563 17256.92161316156 0.6360651341330201 0.7411028948473706 0.6486995849115283 0.8398300735628137 0.9592300102497364 1.0931131624696748 0.982355556960735 0.7621882633032512 1.0718980990252502 1.0 14.074887510953747 -5.998790337113558 2.76960229420118 0.9718320071159345 0.6812245384129376 0.7026505711100979 0.08805443640305527 0.15992381224952032 2.484303332491089 0.027692555717133072 0.041466438155818824 1.0027892344260536e-06 5.998790337113558 -0.2906074687029969 LES(ph)FT(ph)S(ph)LQMS(ph)KK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LESFTSLQMSKK 12 1 Q7Z443 Q7Z443 PKD1L3 Polycystic kidney disease protein 1-like 3 4 LES(1)FT(1)S(1)LQMS(1)KK 42.317 0.044586 0.0 1569.1 2781.4 3277.1 2966.4 3836.6 4038.7 2515.7 2422.7 2910.3 2974.0 True False 1834.7176388623477 3057.519010367777 3355.238492470957 2800.20222519856 3084.8457712635422 3826.903462274983 2277.394683909245 2359.106692062835 2952.857631753328 3513.1626578289547 0.5222410168722893 0.8703038567127563 0.9550478640645718 0.7970602269036452 0.8780822500173956 1.0893043775661422 0.6482462970606141 0.6715051142894428 0.8405126432654613 1.0 11.778554658891217 -4.7595957960884085 24.979242304775795 0.8527948298283474 0.5222405973958376 0.38090405225392654 0.12921729902635132 55.01872887150109 745256.3655120543 0.03347384829115539 0.2100967403349409 1.7394189770382344e-05 4.7595957960884085 -0.3305542324325098 LES(ph)LNIQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LESLNIQR 8 0 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 LES(1)LNIQR;LES(1)LNIQR 82.171 0.016847 8515100.0 31947.0 25598.1 36790.0 31339.7 37051.0 39543.0 37069.0 47091.0 34154.0 25690.2 True False 37354.996117988296 28139.310196050676 37667.21312685196 29583.83821367829 29791.12252282896 37469.29546852694 33557.555963680796 45854.91114703882 34653.4376369801 30347.629896488685 1.2309032450112483 0.927232548045094 1.2411912645346375 0.9748319165148785 0.9816622459296528 1.2346695803372196 1.1057718865737027 1.5109882156676882 1.1418828341843463 1.0 14.88929622815228 -6.779738769409401 24.86447051941859 1.2247936593409259 1.0672621907179052 0.1311600978652695 0.1568713422757071 379.81789145600897 516077.6344353076 0.053056288600803796 0.04688039324837529 1.6605854586488621e-07 6.779738769409401 -0.1575314686230207 LES(ph)LNIQR ddPTM_PC-9_Lapatinib_30min_R1 2 LESLNIQR 8 0 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 LES(1)LNIQR;LES(1)LNIQR 86.344 0.012546 11484700.0 34793.0 42934.0 48883.0 46658.0 41886.0 44186.0 44269.0 33896.0 46145.0 38785.0 True False 34296.84543974523 42834.58896085711 44864.02843383678 50089.38496652525 39422.34783104443 42296.267782596835 46561.03221011942 35470.9319034317 40947.66417160781 45488.93557223604 0.7539601665394463 0.9416485222617739 0.9862624365565354 1.101133370926733 0.8666359705964559 0.9298144098234773 1.0235682946720284 0.7797705410605654 0.9001675606716114 1.0 15.47322805593274 -9.783898205826523 13.101139411338135 1.000008554674489 0.9258152166242192 0.05198655484975079 0.09961719931651218 0.0 0.0 0.09832410101272161 0.02384709729525598 1.6447571922593585e-10 9.783898205826523 -0.07419333805026984 LES(ph)LSYQLSGLQK ddPTM_PC-9_AZD4547_30min_R2 1 LESLSYQLSGLQK 13 0 Q03252 Q03252 LMNB2 Lamin-B2 1 LES(0.998)LS(0.002)YQLSGLQK 159.13 0.00026101 10758000.0 13146.0 13636.0 19394.0 21013.0 17511.0 14203.0 19660.0 16918.0 14822.0 18698.0 True False 17326.154546213438 18043.57033348641 19136.82288818552 16168.77749761375 15079.899911862032 13314.884164747471 21409.701913533416 14303.711836964632 15605.460660287281 18043.388711228257 0.9602494755007694 1.0000100658618543 1.0606002671924275 0.8961053689184254 0.835757636949756 0.7379370016266249 1.1865676817243498 0.7927397711087134 0.8648852446755817 1.0 14.139182694737404 -5.7813613352370705 23.686958394130926 0.8956241129488925 1.0062589154494532 0.1397528875659495 0.11858790453351838 240.93574331036615 286468.5907330536 0.0334381987610196 0.049689680249257684 1.6543929272950898e-06 5.7813613352370705 0.11063480250056068 LES(ph)LSYQLSGLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LESLSYQLSGLQK 13 0 Q03252 Q03252 LMNB2 Lamin-B2 1 LES(0.998)LS(0.002)YQLSGLQK 110.35 0.00068638 4310600.0 12081.0 14394.0 19528.0 20022.0 21364.0 18872.0 15554.0 18940.0 13757.0 14542.0 True False 14126.074689373536 15822.941193368011 19993.621580352403 18900.23225219981 17177.877562757218 17882.31909774272 14080.612518791735 18442.84506858879 13958.170099312976 17178.349485591338 0.8223185062815287 0.9210978741956437 1.1638849004162144 1.1002356348642652 0.9999725280455776 1.0409800494943853 0.8196720255692849 1.0736098415076532 0.8125443082305813 1.0 14.068303806983787 LES(ph)LSYQLSGLQK ddPTM_PC-9_Lapatinib_30min_R1 1 LESLSYQLSGLQK 13 0 Q03252 Q03252 LMNB2 Lamin-B2 1 LES(0.948)LS(0.052)YQLSGLQK 160.79 0.00029452 4216600.0 20696.0 20299.0 24787.0 20968.0 25487.0 20513.0 21462.0 20464.0 20591.0 16889.0 True False 20400.871244818416 20251.998912666837 22749.10854058696 22510.056667197507 23987.904769369943 19635.706808138537 22573.19734562748 21414.832147504912 18271.824747157374 19808.24114682207 1.029918360424011 1.0224026839412725 1.1484668614425015 1.136398557567485 1.2110062974076037 0.9912897698788762 1.1395861539806125 1.0811072012287468 0.9224354960000479 1.0 14.273813162784874 -8.183810319635137 5.901571615506851 0.9621430159057213 1.0984585584757116 0.3977949810798861 0.06590522829382718 0.21201424891599652 12.329300771765183 0.047452971309254285 0.017257529275375275 6.549221522543665e-09 8.183810319635137 0.13631554256999034 LES(ph)PSFTGTGDTEIAHATEDLENNGSKK ddPTM_PC-9_Lapatinib_30min_R1 1 LESPSFTGTGDTEIAHATEDLENNGSKK 28 1 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 LES(0.621)PS(0.125)FT(0.125)GT(0.125)GDT(0.004)EIAHATEDLENNGSKK 58.861000000000004 0.00075598 3462300.0 13090.0 13314.0 15053.0 12836.0 17400.0 16338.0 13730.0 15517.0 18831.0 13142.0 True False 12903.334199587993 13283.17225100972 13815.40044626037 13780.002259640743 16376.566209716199 15639.26182573818 14440.87221859405 16237.976467593506 16710.054480779003 15413.577189385744 0.8371407909433003 0.861783873256684 0.8963137029458725 0.8940171441273264 1.0624766729032633 1.014641937661807 0.9368929769617965 1.0534852661441543 1.0841126803637804 1.0 13.911914101524228 -6.15747144692404 4.706010886349711 1.0227468799706425 0.8693908631243455 0.7760145859329529 0.04036645620499809 0.11690202298616667 4.170971321075295 0.012980434018697065 0.01697324520203326 6.958707038333857e-07 6.15747144692404 -0.15335601684629696 LES(ph)PVAH ddPTM_PC-9_Lapatinib_30min_R1 1 LESPVAH 7 0 Q86TM6-2;Q86TM6-3;Q86TM6 Q86TM6-2 SYVN1 E3 ubiquitin-protein ligase synoviolin 1 LES(1)PVAH 86.95299999999999 0.018267 2572900.0 51193.0 55624.0 34342.0 22114.0 26161.0 37632.0 32887.0 25192.0 46162.0 13349.0 True False 50462.97843235361 55495.20604552838 31518.533323953598 23740.337330141458 24622.261414504927 36022.5670844766 34589.72794267316 26362.512287917496 40962.74945258989 15656.35686357558 3.2231622510952995 3.5445797850097325 2.0131460721415513 1.516338541399322 1.5726686373500127 2.30082690362551 2.2093088605527353 1.6838216270638109 2.616365340259296 1.0 13.934460925108354 -5.289052329042002 6.714558943974472 1.8902310707496126 3.3863349257171724 0.6558403082166405 0.4402009389100574 0.09831712690641985 17.219055934233197 0.11190156762366882 0.24503849664344418 5.139817171291054e-06 5.289052329042002 1.4961038549675598 LES(ph)SEGEIIQTVDR ddPTM_PC-9_AZD4547_30min_R2 1 LESSEGEIIQTVDR 14 0 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 LES(0.581)S(0.419)EGEIIQTVDR 113.25 0.00022658 2592400.0 5171.5 6420.3 7556.0 7967.6 6826.6 7484.0 6113.4 9041.1 6267.6 6365.0 True False 6815.929426117665 8495.536419190576 7455.802502997301 6130.79291819289 5878.8444256934135 7016.024296906996 6657.480756774933 7644.005738809616 6598.892540441 6142.163287355222 1.1096952502304058 1.3831505321065312 1.2138724019835891 0.9981488005723098 0.9571292964151736 1.1422725135541054 1.083898366961456 1.2445135990679723 1.0743596729227372 1.0 12.584531151050486 -5.604249938990014 6.49772804133619 1.081006871705334 1.258943877697957 0.3665610950254885 0.09854957637692743 0.21580670447390093 13.798468935931245 0.02739403553906963 0.04790913137973036 2.4874253785631774e-06 5.604249938990014 0.17793700599262285 LESDYEILER ddPTM_PC-9_Lapatinib_30min_R1 1 LESDYEILER 10 0 J3KR24;A0A0A0MSX9;P41252;Q5TCD1 J3KR24 IARS Isoleucine--tRNA ligase, cytoplasmic 0 94.69200000000001 0.023885 0.0 7727.8 7904.6 8793.9 10008.0 9405.1 9852.4 8518.3 9461.1 7863.3 7070.5 False True 7617.6001548950435 7886.297384357178 8070.899487435657 10744.021705709312 8851.910509138039 9431.03581906616 8959.335893637995 9900.697245443645 6977.652349780125 8292.62650415095 0.9185992099224515 0.9510011551116669 0.9732621484153053 1.295611432678331 1.0674435300694096 1.1372797043669298 1.0803978557521332 1.1939157323060143 0.8414285083606982 1.0 13.017613400179352 -5.546977131568055 24.992995476914125 1.099851591647218 0.941632890891909 0.24486095386483608 0.11285863591250316 268.20905610645093 278164.56562074006 0.02927029720543093 0.05070037495504545 2.8380684672890945e-06 5.546977131568055 -0.15821870075530897 LESEST(ph)SPSLEMK ddPTM_PC-9_AZD4547_30min_R2 1 LESESTSPSLEMK 13 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 LESES(0.003)T(0.756)S(0.212)PS(0.029)LEMK 143.55 0.00033053 7276600.0 45306.0 42733.0 54336.0 63148.0 55932.0 58289.0 43269.0 54397.0 46432.0 53374.0 True False 59712.36557665804 56545.60656063905 53615.46913748829 48590.20422687444 48166.80725659686 54644.17961550131 47119.85717684016 45991.193568705836 48886.300727193266 51505.392505781194 1.1593420158861163 1.097857987477566 1.040968072061003 0.9434003288378098 0.9351798891968527 1.0609409414629314 0.9148528898513144 0.8929393861728863 0.9491491734910291 1.0 15.65243586687585 -5.320023303569243 1.4945489990105667 0.9524601490541135 1.1617642512688702 0.7010518566243044 0.045436619065043635 0.29634845133966486 1.1094585549694802 0.014429522783392889 0.06756583118729617 4.7860441046224035e-06 5.320023303569243 0.2093041022147567 LESEST(ph)SPSLEMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LESESTSPSLEMK 13 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 LESES(0.002)T(0.834)S(0.139)PS(0.024)LEMK 166.62 0.0011283 11996000.0 89941.0 83254.0 91077.0 109520.0 110450.0 105910.0 104460.0 89503.0 92511.0 77522.0 True False 105166.23488427654 91518.90691348207 93248.6210914459 103383.94946863047 88808.1153719592 100355.89315610062 94564.79257509232 87153.64108626738 93863.79836138296 91576.12493618566 1.1484023260163179 0.9993751862426646 1.0182634519251137 1.1289399888963747 0.9697736766416428 1.0958739870903371 1.0326358823436708 0.9517070213115038 1.0249811119087147 1.0 16.482683897895384 -7.53550057327656 20.58817087704029 0.9914404353571062 1.055281169736263 0.23067179024224693 0.055072004983571336 42.76146481009076 69742.14449706706 0.024533331498579163 0.014193165828707988 2.914066288148132e-08 7.53550057327656 0.06384073437915672 LESEST(ph)SPSLEMK ddPTM_PC-9_Lapatinib_30min_R1 2 LESESTSPSLEMK 13 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 LESES(0.027)T(0.637)S(0.118)PS(0.218)LEMK;LES(0.007)ES(0.115)T(0.713)S(0.163)PS(0.002)LEMK 107.97 0.0036271000000000003 34650000.0 92368.0 84476.0 94075.0 82358.0 90942.0 88978.0 85920.0 77154.0 82646.0 70845.0 True False 91050.81538178353 84280.40101219008 86340.51664000143 88414.88205823429 85592.97035885125 85172.61835784858 90368.51719021119 80738.85650452462 73337.5371790379 83090.46385497147 1.0958034310737064 1.0143209834439673 1.0391146304189935 1.064079774696603 1.0301178545380096 1.0250588864988328 1.0875919208724487 0.9716982281558637 0.882622791792851 1.0 16.34239529049708 -7.931865000886364 5.66460494293192 0.936644438510434 1.0473290384750134 0.616350462925752 0.03631689169710516 0.11364697300764068 6.653490105339237 0.01920952588151149 0.008939537528498187 1.1698629828424262e-08 7.931865000886364 0.11068459996457936 LESESTS(ph)PSLEMK ddPTM_PC-9_AZD4547_30min_R2 2 LESESTSPSLEMK 13 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 LESES(0.001)T(0.041)S(0.823)PS(0.135)LEMK;LES(0.009)ES(0.066)T(0.37)S(0.524)PS(0.03)LEMK 174.46 0.00015763 38833500.0 113105.0 102252.0 131480.0 177166.0 159637.0 135319.0 124883.0 138489.0 107382.0 130468.0 True False 149070.03726985207 135302.95935315732 129736.48929249412 136323.11588741417 137474.15808519928 126857.48153836933 135997.34506957233 117088.70721062731 113057.99329530216 125900.3550313684 1.1840319054915365 1.0746829055362572 1.030469606381729 1.0827857939991425 1.0919282797172989 1.0076022542332186 1.08019826501433 0.9300109374707828 0.8979958258825678 1.0 16.94192282581203 -7.761437530364026 24.999999999999872 0.9355025014404011 1.0747140826809574 0.6130195722269216 0.04939671501460164 0.038903857114036274 434110.9234324001 0.02498483505658123 0.013216404575902221 1.7320581549398e-08 7.761437530364026 0.13921158124055621 LESESTS(ph)PSLEMK ddPTM_PC-9_Lapatinib_30min_R1 1 LESESTSPSLEMK 13 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 LES(0.008)ES(0.103)T(0.24)S(0.585)PS(0.064)LEMK 130.19 7.3613e-05 26047000.0 76201.0 62713.0 75770.0 64206.0 80852.0 74796.0 71290.0 70400.0 76725.0 58076.0 True False 75114.3597664481 62567.791901575256 69540.4830806581 68927.92342493733 76096.4443211479 71597.14943799187 74981.04737535105 73671.04100783549 68083.42254993194 68114.35921859431 1.1027683535183708 0.918569779109 1.0209371985352902 1.011944092489105 1.1171865256331235 1.0511315126406828 1.1008111686806006 1.0815787134018031 0.9995458128210076 1.0 16.055671345036895 -6.051704367528042 19.036746622067387 1.0642465786995274 1.0065229384942946 0.12858068387081534 0.05489311078221542 39.37230725893437 14495.678095642652 0.01545022838364722 0.01994826126075795 8.87760121514e-07 6.051704367528042 -0.057723640205232796 LESESTSPS(ph)LEMK ddPTM_PC-9_Lapatinib_30min_R1 1 LESESTSPSLEMK 13 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 LESES(0.009)T(0.056)S(0.383)PS(0.552)LEMK 115.57 0.00025299 4878300.0 54870.0 54379.0 58861.0 49134.0 50828.0 51073.0 51708.0 51285.0 54492.0 42973.0 True False 54087.54373807437 54253.08876653579 54021.675790030626 52747.47826621914 47838.396971692804 48888.726846977974 54385.1872308129 53667.88832509719 48354.53713380117 50400.8257920768 1.073147967083054 1.0764325368467391 1.0718410847649849 1.0465598020917992 0.9491589913436137 0.9699985283706098 1.0790534951782964 1.064821607219261 0.9593996997843374 1.0 15.621159751297935 -6.012945073364952 14.395610246951787 1.0080398017100922 1.0715966865886901 0.3908729688260205 0.03954435107306601 2.936587154939124 3267.8400365107877 0.012490645146729608 0.017036681871978897 9.706327185584587e-07 6.012945073364952 0.0635568848785979 LESLSET(ph)PGPSSPR ddPTM_PC-9_AZD4547_30min_R2 1 LESLSETPGPSSPR 14 0 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895;Q12774-2;C9J591 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 LESLS(0.107)ET(0.471)PGPS(0.13)S(0.292)PR 164.53 0.0012693 34565000.0 22413.0 30682.0 40164.0 47916.0 41379.0 41179.0 34552.0 56142.0 39745.0 39160.0 True False 29539.867780639146 40599.35648078831 39631.39911730862 36869.70649482037 35634.24010353143 38604.07062030105 37627.061063906745 47466.54391481667 41845.839558974345 37789.020319376315 0.781705043713255 1.0743691193277904 1.0487543414029081 0.97567246208591 0.942978669527984 1.0215684422098346 0.9957141187016556 1.2560935296456524 1.1073544433095 1.0 15.205679496752822 -7.63399203807022 9.529828793917963 1.1359974072061623 0.9831095787217906 0.32169106585664464 0.09491945828905725 0.3134481997598256 25.154573005001783 0.043100788145019345 0.024828877007963636 2.3227793795294985e-08 7.63399203807022 -0.15288782848437166 LESLSETPGPS(ph)SPRQPR ddPTM_PC-9_AZD4547_30min_R2 1 LESLSETPGPSSPRQPR 17 1 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895;Q12774-2;C9J591 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 LESLSETPGPS(0.5)S(0.5)PRQPR 60.13399999999999 0.017237 9362600.0 17619.0 16510.0 55871.0 101880.0 69366.0 27927.0 24267.0 70921.0 26552.0 40535.0 True False 23221.475502033678 21846.534629353206 55130.11403453708 78393.14003030928 59735.728244316255 26180.72027521669 26426.715988591845 59961.789052451175 27955.484513017665 39115.88198789374 0.5936584916894028 0.5585080412123814 1.4094048563598718 2.0041255890528493 1.5271476752794249 0.6693117717074499 0.6756006676973522 1.5329269341544998 0.7146837318322469 1.0 15.255466874881494 LESLSETPGPS(ph)SPRQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LESLSETPGPSSPRQPR 17 1 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895;Q12774-2;C9J591 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 LESLSET(0.002)PGPS(0.534)S(0.464)PRQPR 49.528 0.041104 6547800.0 17980.0 25934.0 55639.0 25284.0 36165.0 31313.0 32139.0 20181.0 26474.0 25680.0 True False 21023.658878812697 28508.556128164924 56965.64477208255 23867.41945183398 29078.72786262473 29670.891156613903 29094.56125378989 19651.270133537 26861.13216611263 30335.580717231864 0.6930363085770892 0.9397728823424464 1.8778491601356988 0.78677971172895 0.9585683601602132 0.9780887807352773 0.9590903014183267 0.6477960753978336 0.88546622583211 1.0 14.888723308848464 LESLSETPGPSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 LESLSETPGPSSPR 14 0 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895;Q12774-2;C9J591 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 LESLSETPGPSS(1)PR;LESLSETPGPS(0.078)S(0.922)PR;LESLSETPGPS(0.009)S(0.991)PR 278.36 7.5794e-70 224089000.0 476292.0 499103.0 833264.0 1034967.0 894213.0 820707.0 808416.0 1007469.0 829994.0 839537.0 True False 627742.9485109623 660428.2842588779 822214.3749149748 796371.348230752 770066.9601899325 769388.0615501925 880363.4578906918 851787.8153844973 873865.7883736667 810145.0651651758 0.7748525239525781 0.8151975648018382 1.0148977143338376 0.9829984560461211 0.9505297178264339 0.9496917214367361 1.0866738510728318 1.051401597084136 1.0786534732461763 1.0 19.62782073558956 -3.6521485139596903 0.5010331284610751 1.042035002674233 3.0977913940110886e-18 0.7588467472628905 0.04860507213057744 6.45068250097572 0.520589481346367 0.029913982901063337 5.053833463671854 0.00022276732304325034 3.6521485139596903 -1.042035002674233 LESLSETPGPSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LESLSETPGPSSPR 14 0 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895;Q12774-2;C9J591 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 LES(0.006)LS(0.073)ET(0.273)PGPS(0.186)S(0.462)PR;LESLS(0.001)ET(0.017)PGPS(0.035)S(0.948)PR;LESLSETPGPS(0.001)S(0.999)PR;LESLSETPGPS(0.016)S(0.984)PR;LESLSETPGPS(0.013)S(0.987)PR;LESLSETPGPS(0.002)S(0.998)PR 237.05 5.878199999999999e-27 222930300.0 385586.0 452304.0 536654.0 570894.0 706049.0 521157.0 570318.0 561669.0 497878.0 413104.0 True False 450858.09412935824 497205.75194700115 549449.8666316291 538908.6600433204 567703.7668651548 493826.60947553534 516293.3502952459 546925.7838874982 505158.52385736414 487996.4850705348 0.9238961917198879 1.0188715844441691 1.1259299676148524 1.1043289788561217 1.1633357703039586 1.0119470622911513 1.0579857972145457 1.120757629654742 1.0351683655761348 1.0 18.8965112308529 -4.902818782881038 3.180816871971512 1.0825921431300363 0.9190095575039945 0.4656292545341396 0.050266695404181064 0.237295546609417 4.1677964903331555 0.01276229479168797 0.08318904303740234 1.2507808319565654e-05 4.902818782881038 -0.16358258562604178 LESLSETPGPSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 LESLSETPGPSSPR 14 0 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895;Q12774-2;C9J591 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 LESLSETPGPS(0.016)S(0.984)PR;LESLSETPGPSS(1)PR;LESLS(0.001)ET(0.003)PGPS(0.009)S(0.987)PR;LESLSET(0.002)PGPS(0.261)S(0.737)PR 246.66 4.4641999999999997e-35 254457000.0 611604.0 863323.0 988375.0 895665.0 991386.0 900568.0 805303.0 842463.0 936995.0 737288.0 True False 602882.4148055624 861324.0286359079 907114.6227378298 961535.1919508517 933074.6246198677 862052.8059665422 846997.6489621584 881606.906542389 831460.7561052272 864727.2484254921 0.6971937288934741 0.9960644008896669 1.0490182012762028 1.1119519983921275 1.079039230368678 0.9969071837809904 0.979496888185707 1.0195202107342305 0.9615294968663969 1.0 19.721885625225802 -4.761745900630165 4.289207024420566 1.0276572622386542 0.6659879692323434 0.8361238306675592 0.04322010607013422 0.09193852352465239 3.4727304523061115 0.012093182912466938 0.10451941880698516 1.730828745685499e-05 4.761745900630165 -0.3616692930063108 LESLSETPGPSS(ph)PRQPR ddPTM_PC-9_AZD4547_30min_R2 1 LESLSETPGPSSPRQPR 17 1 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895;Q12774-2;C9J591 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 LESLSETPGPS(0.058)S(0.942)PRQPR 65.528 0.01008 8454600.0 23130.0 13936.0 66004.0 105690.0 68952.0 38416.0 28360.0 69473.0 24519.0 39714.0 True False 30484.85886611266 18440.53946666665 65128.743833752545 81324.80339422249 59379.20499815603 36013.84144708434 30883.98505940019 58737.544180721394 25815.024283469415 38323.6249480008 0.7954586474394287 0.481179415874349 1.6994411129459213 2.122054046415693 1.5494151474116653 0.9397295139995114 0.8058732727215904 1.5326719291408135 0.6736060150493695 1.0 15.225946408451406 -6.775771206183413 24.84005756730558 1.012136662632122 1.3469622228645732 0.11180655062702294 0.47468166136159434 604.999409982838 1048583.8999873453 0.18666190322465684 0.16538184324551777 1.6758254972648343e-07 6.775771206183413 0.33482556023245125 LESPSFT(ph)GTGDTEIAHATEDLENNGSKK ddPTM_PC-9_Lapatinib_30min_R1 1 LESPSFTGTGDTEIAHATEDLENNGSKK 28 1 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 LES(0.041)PS(0.224)FT(0.245)GT(0.245)GDT(0.245)EIAHAT(0.001)EDLENNGSKK 64.532 0.00086417 3529600.0 34545.0 30583.0 40276.0 29013.0 41160.0 40218.0 31372.0 36343.0 45840.0 30291.0 True False 34052.38196522288 30512.186942513923 36964.66274985599 31146.712804530776 38739.0497236735 38497.96989273706 32996.28865562508 38031.62845664437 40677.01648340022 35526.75898977957 0.9584995348159723 0.8588508439875349 1.0404738231396249 0.8767113491408305 1.0904189074724788 1.0836330413312472 0.9287728347276919 1.070506557256895 1.1449684024118916 1.0 15.11661846105152 -6.267707783284214 24.98148428450224 1.0518905842897082 0.935923665194349 0.4049920285723103 0.0708797524579071 536.9584868189694 2139938.4747183663 0.021773780802666964 0.02529833853014849 5.398737564709355e-07 6.267707783284214 -0.11596691909535917 LESPTVSTLTPS(ph)SPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LESPTVSTLTPSSPGK 16 0 A0A087WTV6;A0A087WZR9;Q96C36 A0A087WTV6 PYCR2 Pyrroline-5-carboxylate reductase;Pyrroline-5-carboxylate reductase 2 1 LESPTVSTLTPS(0.956)S(0.044)PGK 238.65 3.0616999999999995e-37 6810500.0 29370.0 40483.0 34178.0 29633.0 39144.0 26890.0 33809.0 33220.0 26321.0 21761.0 True False 34341.76091605833 44501.884697173606 34992.93314078681 27972.759081482236 31474.014197555185 25479.841062860403 30606.366764036888 32348.01019949947 26705.894830560184 25706.097040018773 1.335938352002473 1.731180140956206 1.3612697830522644 1.088176047804331 1.2243793427122378 0.9911983535732345 1.1906267496146719 1.2583789032283155 1.0388934107338406 1.0 14.649822961776671 -5.577819473398532 4.122425433897288 1.1279774416438229 1.5388221372883737 0.6542655525975802 0.12444693208894703 0.11552305164877527 4.051191391178429 0.032352843240692326 0.06045572777397298 2.6435073764632214e-06 5.577819473398532 0.41084469564455084 LESPTVSTLTPSS(ph)PGK ddPTM_PC-9_AZD4547_30min_R2 2 LESPTVSTLTPSSPGK 16 0 A0A087WTV6;A0A087WZR9;Q96C36 A0A087WTV6 PYCR2 Pyrroline-5-carboxylate reductase;Pyrroline-5-carboxylate reductase 2 1 LESPTVSTLTPS(0.002)S(0.998)PGK;LESPTVSTLTPS(0.002)S(0.998)PGK 249.36 2.7484999999999998e-47 11898800.0 107817.0 111663.0 107970.0 138639.0 129872.0 125510.0 124426.0 139667.0 108205.0 132105.0 True False 142100.56326708468 147755.88106102153 106538.24725365531 106677.92050119785 111841.51455390011 117661.83985900546 135499.6729548985 118084.67437837471 113924.49539511433 127480.04415963244 1.114688688757781 1.1590510658750588 0.8357249007558117 0.8368205486939913 0.8773256652927612 0.9229824215597817 1.0629088956481987 0.9262992898755769 0.8936653273547376 1.0 16.959911898421034 -5.251725285726094 24.986405131467507 0.9176256413782612 1.136869907534467 0.6299035091281902 0.06664539482274358 449.58089902984864 1156397.5431087527 0.018535208796295673 0.04771441970131311 5.601117898503328e-06 5.251725285726094 0.21924426615620585 LESPTVSTLTPSS(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LESPTVSTLTPSSPGK 16 0 A0A087WTV6;A0A087WZR9;Q96C36 A0A087WTV6 PYCR2 Pyrroline-5-carboxylate reductase;Pyrroline-5-carboxylate reductase 2 1 LESPTVSTLT(0.002)PS(0.196)S(0.802)PGK 171.76 2.2126999999999997e-05 5319500.0 28370.0 32148.0 28884.0 26621.0 36041.0 22309.0 29486.0 28199.0 26511.0 21536.0 True False 33172.48066695863 35339.4409812696 29572.704103179985 25129.511676446484 28979.024772483303 21139.076767250008 26692.872619846545 27458.80612931023 26898.673221115514 25440.306321117794 1.303934011180613 1.3891122431939673 1.1624350638668184 0.9877833764755686 1.1390988931775576 0.8309285470239259 1.0492355038071615 1.079342590561376 1.0573250526778109 1.0 14.634828421449114 -5.485722744283341 3.2019197654383826 1.0224751808308736 1.3451004753054556 0.7303573564158639 0.07882303378785592 0.1228495932432233 2.5251408460396756 0.02172696577581246 0.04770920743395957 3.2679639400454704e-06 5.485722744283341 0.322625294474582 LESPTVSTLTPSS(ph)PGK ddPTM_PC-9_Lapatinib_30min_R1 2 LESPTVSTLTPSSPGK 16 0 A0A087WTV6;A0A087WZR9;Q96C36 A0A087WTV6 PYCR2 Pyrroline-5-carboxylate reductase;Pyrroline-5-carboxylate reductase 2 1 LESPTVSTLTPS(0.163)S(0.837)PGK;LESPTVSTLTPS(0.205)S(0.795)PGK 258.42 1.4868e-57 9356000.0 69690.0 110368.0 92065.0 94688.0 93403.0 70041.0 70741.0 59652.0 97744.0 56626.0 True False 68696.20782041918 110112.44967698946 84495.77108117707 101651.67138990836 87909.21917736341 67045.50970354557 74403.6228416286 62423.64969033243 86735.04143004947 66413.72865059781 1.034367580561987 1.6579772272129205 1.2722636237713554 1.5305822072526167 1.323660347996018 1.0095128080561708 1.1203048579468498 0.9399208711611847 1.305980603594205 1.0 16.019193877279463 -6.662126125814438 5.127796639198691 1.0749645732618727 1.390848199579404 0.3964831939005147 0.1779508640768376 0.1961860874986121 8.262170920881747 0.055519520281303095 0.05512396190592455 2.177077423680968e-07 6.662126125814438 0.3158836263175313 LESS(ph)EGEIIQTVDR ddPTM_PC-9_AZD4547_30min_R2 1 LESSEGEIIQTVDR 14 0 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 LES(0.056)S(0.944)EGEIIQTVDR 92.15100000000001 0.004259000000000001 2736600.0 3859.3 5610.9 5779.7 7109.2 8358.6 5064.2 6868.5 9189.0 7200.4 7692.3 True False 5086.477121573219 7424.5136978702585 5703.0574016111095 5470.2837760450975 7198.152669938324 4747.534773436186 7479.783193952411 7769.051192213504 7580.9984440920525 7422.994918353898 0.6852324671537269 1.000204604682216 0.7682960131778998 0.7369375617541406 0.9697100360584061 0.6395713355127804 1.0076503185335746 1.0466194949162575 1.0212856842118374 1.0 12.857785665861723 -7.408201387387049 9.110702776243835 1.0257466260372472 0.8126352021809846 0.4984667851181912 0.10717567001380875 0.28839943149966313 21.061289623825726 0.04259734958385226 0.028659893960955224 3.9065970035155213e-08 7.408201387387049 -0.21311142385626258 LESS(ph)EGEIIQTVDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LESSEGEIIQTVDR 14 0 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 LES(0.105)S(0.895)EGEIIQTVDR;LES(0.079)S(0.921)EGEIIQTVDR 218.68 1.3194000000000001e-15 3856800.0 12853.3 17192.1 17623.4 12328.8 15719.8 11619.0 15163.6 9879.099999999999 13043.900000000001 11460.900000000001 True False 15029.10982575324 18898.818069369332 18043.608693116697 11638.05730650889 12639.618035528505 11009.679185919493 13727.19403304297 9619.784092771682 13234.642360865626 13538.670445565522 1.1100875736786915 1.3959138857360607 1.3327459860747797 0.8596159684439943 0.93359374440409 0.8132023916370327 1.0139248228424969 0.7105412700198018 0.9775437266220275 1.0 13.724798446691981 -5.7622761357523 24.99999841096357 0.8915219676440297 1.2912156863433664 0.7117726827398546 0.11014518462539204 10.358411085412383 309499.97675789084 0.02877086641752396 0.04565175152015669 1.7287168464694563e-06 5.7622761357523 0.3996937186993367 LESS(ph)EGEIIQTVDR ddPTM_PC-9_Lapatinib_30min_R1 2 LESSEGEIIQTVDR 14 0 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 LES(0.053)S(0.947)EGEIIQTVDR;LES(0.031)S(0.969)EGEIIQTVDR 220.27 8.1572e-16 4192800.0 14718.1 19584.3 20728.2 15633.9 19616.9 17383.9 16937.4 17182.8 15880.4 15768.900000000001 True False 14508.217195031028 19538.953756605795 19024.00740916588 16783.669159161534 18463.072510309314 16640.431120850157 17814.33569666531 17981.17561689539 14091.782123974452 18494.533354261508 0.7844597599261971 1.056471843995114 1.0286286787972603 0.9074935191751807 0.998298911178262 0.899748633939762 0.9632216912658967 0.9722427309987883 0.7619431025399419 1.0 14.17481127903888 LESTS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 LESTSPK 7 0 Q03111 Q03111 MLLT1 Protein ENL 1 LES(0.163)T(0.098)S(0.739)PK;LES(0.03)T(0.197)S(0.773)PK 91.069 0.015505000000000001 80554000.0 486990.0 350640.0 302699.0 326190.0 303510.0 335130.0 352290.0 269976.0 451120.0 446030.0 True False 641842.6899787383 463977.5228610784 298685.0134799866 250991.93508526272 261372.87546395077 314174.2681216514 383643.12752384023 228257.41263130214 474965.28222026664 430414.62546096504 1.4912195172070146 1.077978059793317 0.6939471751455965 0.583139884748237 0.6072583504429616 0.7299339974453176 0.8913338553794878 0.5303198337808416 1.1035063729806782 1.0 18.71536757584787 -4.926013200363333 2.5053778993894387 0.7421856793308008 1.5443951154217817 0.6158373116924327 0.17730849279497768 0.23052271011058267 2.3276678906762496 0.045036628048127206 0.3501610702470664 1.1857327073214209e-05 4.926013200363333 0.8022094360909808 LESTS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LESTSPK 7 0 Q03111 Q03111 MLLT1 Protein ENL 1 LES(0.036)T(0.038)S(0.927)PK;LES(0.108)T(0.198)S(0.693)PK 115.49 0.0082036 67922000.0 594680.0 852430.0 611160.0 701070.0 1144900.0 1012020.0 655880.0 792970.0 911400.0 1041630.0 True False 695347.5785346128 937053.6168863915 625732.3722372061 661791.3207996065 920565.06373342 958947.8896406097 593750.2982400105 772155.3777211643 924727.5008006009 1230469.273461456 0.5651076329427696 0.7615416630846447 0.5085314893536079 0.5378365271470039 0.7481414478102012 0.7793350962295674 0.48253971963860626 0.627529182869394 0.7515242523685559 1.0 20.2307772014573 -8.626403763470504 2.64173313556957 0.9994828785072155 0.6288672645339095 0.5582534019703091 0.10147200386000542 0.3274668892969735 5.069372759537939 0.10002713713873587 0.026915419153862117 2.3637211247031986e-09 8.626403763470504 -0.370615613973306 LESTS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 LESTSPK 7 0 Q03111 Q03111 MLLT1 Protein ENL 1 LES(0.053)T(0.31)S(0.638)PK;LES(0.234)T(0.14)S(0.626)PK 91.069 0.015505000000000001 138217000.0 917430.0 1176460.0 702830.0 1019950.0 1192150.0 725100.0 1357550.0 1307070.0 907030.0 887070.0 True False 904347.2799639443 1173735.9791514846 645046.0304022556 1094960.5254534583 1122030.0808570785 694089.1632906566 1427837.296456835 1367801.2438936327 804870.7299506654 1040398.8675535254 0.8692313190329558 1.1281596085465744 0.6199987817355731 1.0524430193087708 1.0784614592050712 0.6671375613112611 1.3723941278544087 1.3146892855717796 0.7736174606219064 1.0 19.98870530338342 -7.26399904059276 24.98663215890492 1.1413993072350577 0.914789010441384 0.1791875045748078 0.21913869347277823 388.414362202695 3791551.985544645 0.08729832674622102 0.0619859997132467 5.445038557137123e-08 7.26399904059276 -0.22661029679367362 LETLGSASTS(ph)TPGRR ddPTM_PC-9_AZD4547_30min_R2 1 LETLGSASTSTPGRR 15 1 Q96FF9;B5MBX0 Q96FF9 CDCA5 Sororin 1 LETLGS(0.001)AS(0.024)T(0.153)S(0.696)T(0.126)PGRR 79.013 0.0051833 12222000.0 31339.0 24537.0 44042.0 34778.0 33002.0 35394.0 29444.0 38919.0 24780.0 41307.0 True False 41304.15010830541 32468.105402812813 43457.97430346841 26760.469414743748 28420.24195598601 33180.807584811075 32064.45895941393 32904.962819649285 26089.820210627353 39860.854502872266 1.0362083458428906 0.8145361108722154 1.0902419139142374 0.6713471085476971 0.7129862696229486 0.8324158625957242 0.8044097237580156 0.8254956706278899 0.6545223512142067 1.0 15.282685017319055 -5.765116245274789 24.99963283486294 0.7782849426059926 0.9637495179616039 0.3763607824485685 0.1138117830568104 96.82050774951269 658306.0570019953 0.030125197383169197 0.04670948527892417 1.7174486253667127e-06 5.765116245274789 0.18546457535561134 LETLGSASTS(ph)TPGRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LETLGSASTSTPGRR 15 1 Q96FF9;B5MBX0 Q96FF9 CDCA5 Sororin 1 LETLGSAS(0.004)T(0.029)S(0.682)T(0.284)PGRR 91.932 0.0017190999999999999 10683000.0 40876.0 33691.0 26549.0 37074.0 43497.0 38290.0 43529.0 27407.0 39376.0 30437.0 True False 47795.49946219954 37035.61982393787 27182.02884764319 34996.86397552974 34974.07509582712 36282.00499430737 39405.61799733094 26687.59529011685 39951.799507926706 35954.98716084056 1.329314880530809 1.03005515363594 0.7560016285375785 0.9733521477556156 0.9727183308222183 1.0090952009523444 1.0959708543644968 0.7422501688217247 1.1111615567878486 1.0 15.13390427408605 -4.796429934420453 4.025746524215588 0.9529132772608804 1.3564812095909633 0.4751373740275775 0.11645489571210389 0.17865588171398253 5.386701326903999 0.028181354532649108 0.20211601459859482 1.5979753127513425e-05 4.796429934420453 0.4035679323300829 LETLGSASTS(ph)TPGRR ddPTM_PC-9_Lapatinib_30min_R1 2 LETLGSASTSTPGRR 15 1 Q96FF9;B5MBX0 Q96FF9 CDCA5 Sororin 1 LETLGSAS(0.009)T(0.203)S(0.627)T(0.16)PGRR;LETLGSAS(0.056)T(0.262)S(0.341)T(0.341)PGRR 78.848 0.0052609 23766000.0 83044.0 84408.0 91884.0 80607.0 70274.0 65023.0 61767.0 77773.0 97466.0 80385.0 True False 81859.77733159567 84212.55846201222 84329.65220249697 86535.10767706932 66140.62148399983 62242.11786601627 64964.9930317479 81386.61750429522 86488.35271751932 94279.44014372044 0.8682675375119738 0.893222937404357 0.8944649233591554 0.9178576744320333 0.7015381230857382 0.6601876058145214 0.6890685066936617 0.863248841743531 0.917361755497017 1.0 16.524655571057806 -6.239694252046876 24.676036447510132 0.7853359657785844 0.8935090860436921 0.1369196817129994 0.10137281707166233 1183.6532470171037 1343190.857199468 0.031336230263080626 0.04041686117642214 5.758451958346265e-07 6.239694252046876 0.10817312026510761 LETLGSASTST(ph)PGRR ddPTM_PC-9_AZD4547_30min_R2 1 LETLGSASTSTPGRR 15 1 Q96FF9;B5MBX0 Q96FF9 CDCA5 Sororin 1 LETLGSAS(0.019)T(0.082)S(0.199)T(0.7)PGRR 67.994 0.024363 13252000.0 29791.0 10191.0 33081.0 29605.0 39230.0 30447.0 23624.0 37501.0 35001.0 12010.0 True False 39263.918308705695 13485.041454133161 32642.324325258567 22780.024642690467 33783.5916590913 28543.14427684759 25726.490234247907 31706.082137250913 36851.081404042285 11589.533555559496 3.3878773567958484 1.1635534242587693 2.816534778451032 1.96556872056019 2.915008744496479 2.462838054699402 2.219803766123695 2.7357513557602595 3.1796863288225117 1.0 13.500534882854762 -6.24350182541883 24.11476565549929 2.49788299216839 2.2843351976122066 0.0 0.7665798366847016 3082.429016238932 4143928.2801978886 0.21146106841939766 0.2723548512551281 5.708186769119302e-07 6.24350182541883 -0.21354779455618322 LETLGSASTST(ph)PGRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LETLGSASTSTPGRR 15 1 Q96FF9;B5MBX0 Q96FF9 CDCA5 Sororin 1 LETLGSAS(0.014)T(0.044)S(0.142)T(0.8)PGRR 98.572 0.0018932000000000003 11668000.0 35860.0 26655.0 34780.0 47720.0 38967.0 32083.0 38315.0 31900.0 28136.0 23982.0 True False 41930.389732715434 29301.13224324191 35609.28710388453 45046.40311032743 31331.69607695003 30400.51100110637 34685.52582342197 31062.65880084387 28547.435771917535 28329.74675859246 1.4800834645653116 1.0342885339896244 1.2569574803235464 1.5900743304973166 1.10596456593623 1.073095049530785 1.2243500133972003 1.096467930530389 1.0076841143403108 1.0 14.790030084980401 -6.471975495318917 24.999701009165218 1.0947034708600902 1.316968628870739 0.4138940653925922 0.14782487168048422 416.38630222199504 204496.23903224475 0.04653502439504803 0.052765157557639164 3.373063403331286e-07 6.471975495318917 0.22226515801064872 LETVVCTGS(ph)VPVDK ddPTM_PC-9_AZD4547_30min_R2 1 LETVVCTGSVPVDK 14 0 J3KNG8;Q8TF40;Q8TF40-3;A0A087WX11 J3KNG8 FNIP1 Folliculin-interacting protein 1 1 LETVVCT(0.278)GS(0.722)VPVDK 131.86 1.505e-05 3351500.0 15438.0 10444.0 13292.0 19638.0 15569.0 13317.0 14275.0 17446.0 11658.0 17000.0 True False 20346.962869651852 13819.818756448522 13115.739395161489 15110.7625040755 13407.513090501965 12484.28588480899 15545.44734566071 14750.121569197605 12274.218079721295 16404.83517439728 1.2403027920333498 0.8424235056025954 0.7995044909461192 0.9211163869332002 0.8172903261732748 0.7610125766025971 0.9476137480443692 0.8991325674650997 0.7482073394359632 1.0 14.001833478174191 -4.7603202969771745 24.991261164702717 0.8548303816680785 1.2403032527061035 0.681629257190183 0.07799608536330258 15.339024343043828 342396.71549646155 0.018542167195360473 0.11090037378375305 1.7365196539425665e-05 4.7603202969771745 0.3854728710380251 LEVNGRES(ph)EEENLNK ddPTM_PC-9_AZD4547_30min_R2 1 LEVNGRESEEENLNK 15 1 O95793-2;O95793-3;O95793;A0A087X1A5;Q5JW30;Q5JW28 O95793-2 STAU1 Double-stranded RNA-binding protein Staufen homolog 1 1 LEVNGRES(1)EEENLNK 76.52600000000001 0.0065376 4170600.0 9551.8 9390.1 9050.2 10539.0 12908.0 8856.5 9772.4 12647.0 12455.0 7928.5 True False 12589.07371021767 12425.266191586292 8930.188434704372 8109.396375926867 11115.94700829851 8302.701654938111 10642.124668352699 10692.69674914835 13113.34587261354 7650.925628247581 1.6454314578275617 1.6240213008621622 1.1672036651008202 1.0599235661089934 1.4528891729463302 1.085189172965444 1.390959105531162 1.3975690352642307 1.7139554754261948 1.0 12.901418583905187 -5.245642828736743 23.1196153408751 1.2924856414557218 1.6347266448513695 0.31767358368636645 0.20558094291649223 372.28792658364017 544868.046529855 0.0525398307684671 0.13769178829837228 5.68011555856524e-06 5.245642828736743 0.3422410033956478 LEVNGRES(ph)EEENLNK ddPTM_PC-9_Lapatinib_30min_R1 1 LEVNGRESEEENLNK 15 1 O95793-2;O95793-3;O95793;A0A087X1A5;Q5JW30;Q5JW28 O95793-2 STAU1 Double-stranded RNA-binding protein Staufen homolog 1 1 LEVNGRES(1)EEENLNK 68.033 0.013502000000000002 5611800.0 23882.0 30449.0 31156.0 23667.0 27009.0 28657.0 25407.0 29302.0 33727.0 23100.0 True False 23541.43830057759 30378.49721128097 28594.473945637932 25407.550130797572 25420.38372173707 27431.406912729777 26722.45014259422 30663.477892210183 29928.310098945018 27092.804221184775 0.868918481394028 1.1212754856703613 1.0554268842823937 0.9377969856265581 0.9382706756453072 1.0124978827876459 0.9863301681299952 1.1317941709493984 1.1046590029814287 1.0 14.725622105928775 -7.747492354970084 24.83041457311434 1.0886699384092953 0.9933391220667026 0.2415571708162345 0.07225957444069034 283.77440550880226 505216.56109517324 0.03439939071612725 0.019727500537945093 1.7885770137454917e-08 7.747492354970084 -0.09533081634259266 LEVPAERS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 LEVPAERSPR 10 1 Q9UJF2-2 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 LEVPAERS(1)PR;LEVPAERS(1)PR 97.95700000000001 0.0023331 29574000.0 37083.0 38992.0 56791.0 70933.0 57736.0 50031.0 47930.0 60484.0 47822.0 53905.0 True False 48874.62262568334 51595.40146988134 56037.91423341977 54580.492753925486 49720.35299590354 46902.55366095055 52195.67714728674 51137.58758405066 50349.773289452016 52017.80235740507 0.9395749226365716 0.9918796860232294 1.0772833855685258 1.0492656413839367 0.9558334020780778 0.9016634985594248 1.0034194983605713 0.9830785859174402 0.967933495988694 1.0 15.666717829290821 -6.27721139502158 24.704570837086123 0.9661973492217033 1.01736957118282 0.21287389616167995 0.04289160131040405 1083.9925190091578 1697912.4593385623 0.01431025098699902 0.016286550761121246 5.281880909854484e-07 6.27721139502158 0.05117222196111659 LEVPAERS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LEVPAERSPR 10 1 Q9UJF2-2 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 LEVPAERS(1)PR;LEVPAERS(1)PR 100.02 0.0019573 6069000.0 31056.0 25961.0 39383.0 43375.0 45909.0 41029.0 41316.0 47497.0 38726.0 33719.0 True False 36313.16741604045 28538.23650972814 40322.04008085924 40944.83937364734 36913.46101051399 38877.367012573435 37402.249378063505 46250.2540772314 39292.2944876059 39831.987780542855 0.911658429303363 0.7164652858140439 1.012302983798257 1.0279386406532312 0.9267290704619439 0.9760338155045395 0.9390003226586088 1.161133467203556 0.986450756715672 1.0 15.281639857483379 -5.2794574004864145 24.642940964352377 1.0042715299769804 0.8140618624822437 0.5081691684506855 0.07462362308642703 459.3129572803735 628194.2351823592 0.01940325811698606 0.040524888381643843 5.254635547795271e-06 5.2794574004864145 -0.19020966749473678 LEVPAERS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 LEVPAERSPR 10 1 Q9UJF2-2 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 LEVPAERS(1)PR;LEVPAERS(1)PR 116.03 0.0005072 24179000.0 76235.0 50047.0 73522.0 62354.0 62911.0 56923.0 51909.0 49160.0 63346.0 45019.0 True False 75147.87492021329 49931.11924637851 67477.30496312727 66939.72116684628 59210.69866778487 54488.53598399403 54596.59402731231 51444.15306740329 56211.3064170478 52800.47416595317 1.4232424255134848 0.9456566448521616 1.277967783983236 1.267786364123419 1.1214046768156705 1.0319705806568182 1.0340171161288039 0.9743123310921995 1.0645985155431428 1.0 15.688263265076314 -6.589789221829215 3.015185482172989 1.0191804706029477 1.2115384614301559 0.42335926911509225 0.1133053383546156 0.26912271808907157 4.967797510126705 0.03820118067995238 0.03903747719949064 2.571643587745105e-07 6.589789221829215 0.19235799082720817 LEVS(ph)PEAQPTAR ddPTM_PC-9_AZD4547_30min_R2 2 LEVSPEAQPTAR 12 0 Q6WKZ4 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 LEVS(0.89)PEAQPT(0.11)AR;LEVS(0.941)PEAQPT(0.059)AR 152.0 0.00013527 40797000.0 96143.0 94694.0 107359.0 163603.0 133106.0 118914.0 98111.0 139434.0 92114.0 100774.0 True False 126714.4741013692 125301.98365790256 105935.34951287559 125886.85599115312 114626.52947680348 111478.28878172055 106842.68893380873 117887.67917456721 96982.95798554199 97245.93293321834 1.3030310911654042 1.2885061603959431 1.0893550641919856 1.2945205233169323 1.1787282616283903 1.1463542527611514 1.0986854227331109 1.2122633370747151 0.9972957743347791 1.0 16.56935029381514 -1.5228787487147943 0.08975986803938084 0.8611674935856366 2.0632987809428167 0.5884589868877148 0.0700254040589979 112.72685616464426 0.7306366267633303 1.2853282274335343 16.685995037312182 0.029999999762756132 1.5228787487147943 1.2021312873571801 LEVS(ph)PEAQPTAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LEVSPEAQPTAR 12 0 Q6WKZ4 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 LEVS(1)PEAQPTAR;LEVS(0.557)PEAQPT(0.443)AR 139.19 7.168e-05 26634000.0 83826.0 69466.0 74886.0 88793.0 88188.0 74853.0 63717.0 83497.0 67240.0 61571.0 True False 98016.08616103206 76362.12539519946 76671.56624673655 83818.2160807902 70908.19446285514 70927.57690882444 57681.26448886802 81305.29222238419 68223.25779441757 72733.3349042322 1.3476088548681233 1.0498917105306018 1.0541461676092512 1.1524044125180488 0.9749064106055331 0.9751728970246533 0.793051281985307 1.117854589363167 0.9379916084453844 1.0 16.15032910653659 -1.5228787452807824 0.6250579702676958 0.9748298778278078 26.203386265807534 0.557760476390872 0.09287454264398473 152.31089260303338 1.0787592538248143 0.04091579887338136 5284.904108357445 0.029999999999969273 1.5228787452807824 25.228556387979726 LEVS(ph)PEAQPTAR ddPTM_PC-9_Lapatinib_30min_R1 2 LEVSPEAQPTAR 12 0 Q6WKZ4 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 LEVS(0.681)PEAQPT(0.319)AR;LEVS(1)PEAQPTAR 136.33 6.308e-05 30699000.0 96072.0 84696.0 90696.0 78269.0 84227.0 69312.0 64334.0 59404.0 88256.0 56003.0 True False 94701.99566255274 84499.89161570657 83239.32497668431 84025.16335773008 79272.93345665322 66347.68733416362 67664.89973132033 62164.12670496394 78315.67990311883 65683.0439306932 1.441802784939131 1.2864795319910622 1.2672878721107381 1.2792519702100127 1.2069010312661466 1.0101189494837015 1.030173020037231 0.9464257894405395 1.192327200696655 1.0 16.0032333666219 -6.518848963981062 1.9752832599162649 1.0295442623662205 1.3196123906402992 0.7590761414995097 0.07517232637858294 0.16126584431599822 1.2664522325412175 0.027473624411735335 0.029845658598280495 3.0279662907979075e-07 6.518848963981062 0.2900681282740787 LEVTEIVKPS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 LEVTEIVKPSPK 12 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 LEVT(0.001)EIVKPS(0.999)PK 58.07899999999999 0.032913 87981000.0 105210.0 104250.0 94256.0 98809.0 103640.0 102050.0 98411.0 90705.0 96677.0 104110.0 True False 138664.59149605333 137946.77378013774 93006.1038542237 76030.11163383223 89251.37495662064 95668.79736763192 107169.38835263178 76688.62644354411 101787.1488499927 100465.1405886176 1.3802259239735102 1.3730809808448792 0.9257549763958723 0.7567810206443508 0.8883815265046525 0.9522586322690212 1.0667320796520514 0.7633356803586925 1.0131588753435228 1.0 16.61633547609975 -5.264030246394301 6.593930273139612 0.9109880356620784 1.3794583327994006 0.7858440960814865 0.09510681699507868 0.05380293388476343 13.886349163462262 0.02474690325431 0.05824859440536425 5.444647323319467e-06 5.264030246394301 0.46847029713732213 LEVTEIVKPS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LEVTEIVKPSPK 12 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 LEVT(0.003)EIVKPS(0.997)PK 53.981 0.041069999999999995 63880000.0 60323.0 66357.0 41952.0 59432.0 60595.0 48036.0 64623.0 48570.0 42831.0 50552.0 True False 70534.49246644144 72944.4844218646 42952.294783846 56102.217721143745 48721.84473484711 45516.90759745494 58501.44160999607 47295.088964168855 43457.32234670884 59716.677430588185 1.181152326306623 1.2215094268540274 0.7192679940000295 0.9394731946758808 0.8158833818488823 0.7622143353565112 0.9796499759718774 0.7919912995685737 0.7277250546502952 1.0 15.865846277309878 -5.251532247617319 24.793613114277186 0.8392081389253111 1.201330940683649 0.6918793935574361 0.09589630991539153 314.8398402024088 787914.3624944594 0.023315577376213963 0.060092629669300374 5.603608074139469e-06 5.251532247617319 0.3621228017583379 LEVTEIVKPS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 LEVTEIVKPSPK 12 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 LEVTEIVKPS(1)PK;LEVT(0.005)EIVKPS(0.995)PK 77.726 0.0081391 151905000.0 260340.0 293850.0 233470.0 261110.0 268810.0 249020.0 248970.0 267650.0 209260.0 218830.0 True False 256627.50385949132 293169.60837909003 214274.9978202626 280312.90043742635 252999.1243007939 238369.99509397248 261860.44838043378 280085.99610436306 185690.93519450992 256654.47392735406 0.9998949168216317 1.1422735161907662 0.8348773140066634 1.0921800666399792 0.9857577015096382 0.9287583865046631 1.0202839809235247 1.0912959817861632 0.723505545619554 1.0 17.96946788385165 -8.247425459298983 24.998010115524558 0.8617527412985027 1.0096698834440556 0.2516669601360406 0.10351724521424258 909.7947584770586 1622897.629220002 0.06626579233014739 0.024775159778030225 5.656848408143637e-09 8.247425459298983 0.14791714214555296 LEY(ph)DPYTADMQKT(ph)IS(ph)AY(ph)IK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LEYDPYTADMQKTISAYIK 19 1 Q2TBF2;Q2TBF2-2 Q2TBF2 WSCD2 WSC domain-containing protein 2 4 LEY(0.473)DPY(0.473)T(0.058)ADMQKT(0.999)IS(0.999)AY(0.999)IK 40.515 0.033826999999999996 4556300.0 1789.4 1273.1 1893.0 4146.9 4194.7 1378.8 4594.1 1215.6 1079.8 2210.2 True False 2092.3100777390136 1399.4849543752123 1938.1362992424786 3914.5626374311987 3372.7786469059038 1306.4933007613222 4158.913589596316 1183.6917880346643 1095.5900322190987 2610.891764066426 0.8013775624617511 0.5360179895759198 0.742327325060714 1.4993201523353554 1.2918109794229273 0.5004011727879818 1.592909230032144 0.45336685508214314 0.419622922442688 1.0 11.350326935847411 -10.826845227779986 4.920562812044481 1.0000090682300526 0.8861063618146519 0.0073496790221329045 0.4176421563080657 0.0002014592248625198 2.8497254846277245e-05 0.4153958252742404 0.10071044826747766 1.4898919451507133e-11 10.826845227779986 -0.11390270641540079 LFDDEAS(ph)VDEPR ddPTM_PC-9_AZD4547_30min_R2 2 LFDDEASVDEPR 12 0 A0A0U1RR46;A0A0X1KG69;A0A087WUZ6;A0A2R8Y549;Q8NI35-4;Q8NI35-3;Q8NI35-2;Q8NI35;Q8NI35-5 A0A0U1RR46 INADL InaD-like protein 1 LFDDEAS(1)VDEPR;LFDDEAS(1)VDEPR 164.22 0.00063856 21704100.0 13074.900000000001 12615.7 14189.7 21997.9 16552.6 14879.900000000001 13183.900000000001 16665.7 14853.5 15819.3 True False 17232.446225185315 16693.47831154037 14001.535306614727 16926.624019167044 14254.557208673828 13949.457500741104 14357.241559401487 14090.399004687408 15638.625685978746 15265.471122020168 1.1288512544056253 1.0935449144088536 0.917202960504623 1.1088176633311169 0.9337777455234831 0.9137914833574485 0.940504321461224 0.9230241826183969 1.0244443529437037 1.0 13.897984494145819 -4.380312677619221 0.7252606955021584 0.9565611951580464 1.3672058205574487 0.4402694134713704 0.060735905984920395 4.286313770922512 1.1404195032177837 0.024204247017105746 1.6422382492838787 4.1656935936056984e-05 4.380312677619221 0.4106446253994023 LFDDEAS(ph)VDEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LFDDEASVDEPR 12 0 A0A0U1RR46;A0A0X1KG69;A0A087WUZ6;A0A2R8Y549;Q8NI35-4;Q8NI35-3;Q8NI35-2;Q8NI35;Q8NI35-5 A0A0U1RR46 INADL InaD-like protein 1 LFDDEAS(1)VDEPR;LFDDEAS(1)VDEPR;LFDDEAS(1)VDEPR;LFDDEAS(1)VDEPR 161.25 0.00011517 41002700.0 74834.4 83403.20000000001 80267.09999999999 76683.3 94988.2 80007.20000000001 87364.7 84436.5 67822.0 57632.0 True False 87502.38587322703 91682.9185034538 82180.97207867181 72386.98331161302 76375.94408849928 75811.48158737394 79088.88315034621 82220.13134286691 68813.76844338198 68080.22538533897 1.2852834340362012 1.3466894092156994 1.2071195653880638 1.0632600421326088 1.121852103987699 1.1135609666136608 1.1617012532302509 1.2076947583163107 1.0107746860985125 1.0 16.054948192745073 -1.5228787452837782 0.31895027975577356 1.0737083703358383 3.685808675924445 0.582099260603401 0.06938817654801153 43.88790820222875 0.6264552185830738 0.06913322947913736 66.79421870269395 0.029999999999762328 1.5228787452837782 2.6121003055886067 LFDDEAS(ph)VDEPR ddPTM_PC-9_Lapatinib_30min_R1 3 LFDDEASVDEPR 12 0 A0A0U1RR46;A0A0X1KG69;A0A087WUZ6;A0A2R8Y549;Q8NI35-4;Q8NI35-3;Q8NI35-2;Q8NI35;Q8NI35-5 A0A0U1RR46 INADL InaD-like protein 1 LFDDEAS(1)VDEPR;LFDDEAS(1)VDEPR;LFDDEAS(1)VDEPR 107.39 0.0015578 24195300.0 36379.1 35110.6 41168.2 37464.6 32632.1 33721.2 35220.0 28411.7 33081.700000000004 29393.6 True False 35860.3273628901 35029.303562888825 37783.50950984757 40219.871662241894 30712.74403517703 32279.022883956564 37043.519267216456 29731.811304010225 29355.69058025528 34474.24459548993 1.040206327467477 1.016100685422169 1.0959923836820076 1.1666643354820205 0.8908895436448521 0.9363228480481178 1.0745273667885575 0.8624354689384512 0.85152527414903 1.0 15.073231319097825 -6.273048786854693 24.973861207213517 0.9360193572480793 1.0763560213671297 0.49122478905667766 0.07165704262847993 688.571230081786 1481234.0431054486 0.023453850892373767 0.02680575071727556 5.33274986205526e-07 6.273048786854693 0.14033666411905044 LFDDEAS(ph)VDEPRR ddPTM_PC-9_AZD4547_30min_R2 2 LFDDEASVDEPRR 13 1 A0A0U1RR46;A0A0X1KG69;A0A087WUZ6;A0A2R8Y549;Q8NI35-4;Q8NI35-3;Q8NI35-2;Q8NI35;Q8NI35-5 A0A0U1RR46 INADL InaD-like protein 1 LFDDEAS(1)VDEPRR;LFDDEAS(1)VDEPRR 128.21 0.00015815 13962700.0 14823.9 15562.7 19314.2 24810.0 23376.2 24434.0 19788.2 26872.0 20604.9 19581.5 True False 19537.591843725364 20593.038429814376 19058.081088325904 19090.43781067896 20130.818132583485 22906.138117400522 21549.31146517711 22719.549857129303 21694.03294826294 18895.957645144732 1.0339561619807873 1.0898118431751305 1.0085797950136086 1.0102921571473886 1.0653505109732317 1.2122242517455153 1.1404191240190544 1.2023497450507374 1.14807798343246 1.0 14.205790015632967 -6.602809138291405 6.497339301356819 1.1528146300471864 1.0376045368344633 0.4188785674899005 0.058203635466374415 0.1802448610192946 11.792108974837253 0.018268053971668287 0.018264617020430328 2.4956912807079204e-07 6.602809138291405 -0.11521009321272313 LFDDEAS(ph)VDEPRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LFDDEASVDEPRR 13 1 A0A0U1RR46;A0A0X1KG69;A0A087WUZ6;A0A2R8Y549;Q8NI35-4;Q8NI35-3;Q8NI35-2;Q8NI35;Q8NI35-5 A0A0U1RR46 INADL InaD-like protein 1 LFDDEAS(1)VDEPRR;LFDDEAS(1)VDEPRR 120.21 9.909e-05 13961100.0 25236.6 26974.6 26375.3 25639.8 31778.0 28990.0 23460.0 24729.9 23111.6 16402.3 True False 29508.657934429637 29652.46001907911 27004.187180882254 24203.28513135316 25551.329020281726 27469.713366021697 21237.69896430849 24080.76632849494 23449.56342714849 19375.90714946465 1.5229562005433617 1.5303778961336734 1.393699245799099 1.2491433275691504 1.3187165288923106 1.4177252788280768 1.0960879818674854 1.242820072512594 1.2102433835102473 1.0 14.24197623622778 -1.5228787452895765 0.119295789024549 0.9035753053409429 2.943546802921817 0.7731461486406869 0.07844101995465741 45.97844383320886 0.37891866705384253 0.574254977673349 15.569557160887308 0.0299999999993618 1.5228787452895765 2.0399714975808743 LFDDEAS(ph)VDEPRR ddPTM_PC-9_Lapatinib_30min_R1 3 LFDDEASVDEPRR 13 1 A0A0U1RR46;A0A0X1KG69;A0A087WUZ6;A0A2R8Y549;Q8NI35-4;Q8NI35-3;Q8NI35-2;Q8NI35;Q8NI35-5 A0A0U1RR46 INADL InaD-like protein 1 LFDDEAS(1)VDEPRR;LFDDEAS(1)VDEPRR;LFDDEAS(1)VDEPRR 123.1 7.8727e-05 16983800.0 26187.6 26072.9 28903.5 24131.0 25415.3 22967.2 20375.4 20563.7 24734.2 17929.4 True False 25814.160021782336 26012.52980196419 26527.165800736486 25905.674238656196 23920.422022402327 21984.946395158142 21430.33851440212 21519.164573477658 21948.37393332717 21028.472900576224 1.2275812962659298 1.237014685990412 1.2614879799478729 1.2319332155568143 1.1375253988009209 1.0454846863633027 1.0191105467204364 1.0233346318214096 1.043745498643686 1.0 14.360056464105101 -6.544660622688088 1.9475486629035088 1.0231189757003336 1.2436362987350644 0.9830577302555775 0.013231658865687597 0.04001237860286357 0.3069064230400737 0.005206020263038909 0.005558699629688254 2.8532470525943495e-07 6.544660622688088 0.22051732303473082 LFDFVNAK ddPTM_PC-9_Lapatinib_30min_R1 1 LFDFVNAK 8 0 Q08945;A0A0U1RRK2 Q08945 SSRP1 FACT complex subunit SSRP1 0 125.96 0.00014739 0.0 13700.0 15239.0 14856.0 14386.0 15028.0 13980.0 12798.0 13797.0 13806.0 15970.0 False True 13504.63548772769 15203.715031781368 13634.597025818379 15443.994430289176 14144.082586184777 13382.10798897171 13460.617818905073 14438.058988424804 12251.022896374854 18730.393221312595 0.7210011732354494 0.8117136064437582 0.7279397108601059 0.8245419222014009 0.7551407180331253 0.7144595327419353 0.7186511067791547 0.7708358718276288 0.6540718473777094 1.0 14.193093567036588 -11.015841344580672 5.72642707361326 1.0003151949391988 0.7475984984294725 0.7239615606009133 0.047334089998387424 0.00018684440087908495 1.6543867573322882e-05 0.044957376367238636 0.010890355044658753 9.641811916557082e-12 11.015841344580672 -0.2527166965097264 LFDHPESPT(ph)PNPTEPLFLAQAEVYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LFDHPESPTPNPTEPLFLAQAEVYK 25 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 1 LFDHPES(0.46)PT(0.539)PNPT(0.001)EPLFLAQAEVYK 117.03 1.5376e-08 2332200.0 16599.0 18211.0 15117.0 20195.0 22559.0 16449.0 20339.0 16820.0 18791.0 14546.0 True False 19408.882854806012 20018.86772769382 15477.446611541758 19063.539623073393 18138.725891136484 15586.385483190434 18412.342678391735 16378.492822263135 19065.782825920633 17183.074653927353 1.1295349200132776 1.1650340891185222 0.9007379018751014 1.1094370482011635 1.0556158462007676 0.9070777958604759 1.0715394682978592 0.9531759101401376 1.1095675954339737 1.0 14.068700587800613 -5.229246676282092 24.987656929997645 1.0149393000338724 1.1472845619317733 0.35496625242759006 0.07217102415197339 686.378936621691 532758.5716759887 0.017323109440617122 0.04582446241777933 5.8986594519921385e-06 5.229246676282092 0.13234526189790086 LFDQAFGLPR ddPTM_PC-9_Lapatinib_30min_R1 1 LFDQAFGLPR 10 0 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 0 125.71 0.0017060999999999999 6925800.0 31103.0 21368.0 37925.0 17590.0 20923.0 26419.0 21513.0 21221.0 26217.0 21014.0 False True 30659.465516408378 21318.52370884602 34806.95289473356 18883.62727851984 19692.35027620069 25289.120955696944 22626.83787608257 22207.005131069283 23264.16538275096 24646.24190060508 1.243981359919042 0.8649807055704763 1.412262081785338 0.7661868837721761 0.7990001216257328 1.026084262975447 0.9180644240746118 0.9010300726831739 0.9439234377627289 1.0 14.589080058416286 -5.782923138803324 24.999998570714705 0.9044602928008246 1.1428655939103356 0.4027859101785358 0.14694725309606543 240.90802453600455 280336.4963593145 0.03976232629710527 0.05903674753392337 1.6484541082051448e-06 5.782923138803324 0.23840530110951097 LFDSTTLEHQK ddPTM_PC-9_Lapatinib_30min_R1 2 LFDSTTLEHQK 11 0 Q13347 Q13347 EIF3I Eukaryotic translation initiation factor 3 subunit I 0 ; 169.99 0.00088223 8002300.0 64557.0 52750.0 60840.0 59593.0 66081.0 65360.0 50406.0 47151.0 66087.0 48229.0 False True 63636.40534169612 52627.860615950354 55837.97004919156 63975.66801642035 62194.24550024467 62564.705161601654 53015.77604154783 49341.80759318825 58643.586133038174 56565.318388897016 1.1250074631275664 0.9303909553575583 0.9871414435484159 1.1310051784129598 1.0995119849347925 1.1060612216739902 0.9372487869166505 0.8722978849682097 1.0367410244180486 1.0 15.787630151262691 -7.272891163870836 24.80334784721621 0.9509300729981729 1.0584274684937118 0.32057116727241675 0.07160583561799852 840.3680062869377 1820139.002497832 0.031316833862660244 0.021319409107496287 5.334685683338255e-08 7.272891163870836 0.10749739549553894 LFDTPHT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 LFDTPHTPK 9 0 P30291 P30291 WEE1 Wee1-like protein kinase 1 LFDTPHT(1)PK 78.342 0.045595 7827600.0 68862.0 54278.0 88324.0 111090.0 103670.0 84415.0 72176.0 82155.0 68742.0 77742.0 True False 90758.68358142038 71822.3020358592 87152.7660501235 85479.91682339084 89277.20997445831 79136.51670542551 78599.52417656107 69459.8324840898 72375.56178042552 75020.27624282321 1.2097887148223183 0.9573718684184406 1.1617228090180611 1.1394241810935515 1.1900410721694588 1.0548683725087733 1.047710407279129 0.9258807880054247 0.9647466712354222 1.0 16.1949929549111 -7.366703055691337 1.9845241996524985 0.9610449907632923 1.1219331363582072 0.5045658823401236 0.06936193822314736 0.28404181293938263 2.1824569165203402 0.03721660319355104 0.02170920302858324 4.298302182301001e-08 7.366703055691337 0.16088814559491493 LFDTPHT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LFDTPHTPK 9 0 P30291 P30291 WEE1 Wee1-like protein kinase 1 LFDTPHT(1)PK 83.045 0.031226 6120700.0 72527.0 69424.0 69023.0 87809.0 87337.0 89330.0 83544.0 68288.0 73809.0 66485.0 True False 84804.38862645435 76315.95591276769 70668.77009118508 82889.34641061917 70223.94180390038 84645.37754352247 75630.10751381889 66495.5123571168 74888.31699209048 78538.2042050295 1.0797851756969963 0.9717048751654612 0.8998011962012691 1.0554016004011335 0.8941373502833837 1.077760542150286 0.9629722028833405 0.8466645377264496 0.953527238751083 1.0 16.26110699036102 -7.529544194431778 24.978035396657443 0.9210211976107966 0.991564585507268 0.12926080817230634 0.0710056199377018 300.3251824856733 1125413.705386809 0.0317660467099151 0.01839462055752666 2.9543082385223327e-08 7.529544194431778 0.07054338789647141 LFDTPHT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 LFDTPHTPK 9 0 P30291 P30291 WEE1 Wee1-like protein kinase 1 LFDTPHT(1)PK;LFDT(0.002)PHT(0.998)PK 100.93 0.0076779 14902800.0 286900.0 241010.0 279920.0 239870.0 256230.0 236010.0 206442.0 228190.0 254210.0 174171.0 True False 282808.753388984 240451.95615260993 256906.05812244702 257510.83998286334 241159.05516756256 225916.40246618097 217130.5566315362 238792.54044855086 225578.1928500254 204276.22528173082 1.3844428200048429 1.1770922231453356 1.2576405196842213 1.2606011278488878 1.1805537077795725 1.1059358579521663 1.062926223216026 1.1689688318805398 1.1042802095002275 1.0 17.640161780005485 -1.5228787452804207 0.14422770223497147 0.9735529839460214 2.234297254965852 0.7417107740127256 0.053502341348551044 39.58318780447209 0.3791280979288927 0.22001690319653297 10.34701933849634 0.02999999999999426 1.5228787452804207 1.2607442710198309 LFEGNALLR ddPTM_PC-9_Lapatinib_30min_R1 2 LFEGNALLR 9 0 P46781;B5MCT8;C9JM19 P46781 RPS9 40S ribosomal protein S9 0 ; 119.21 0.008068200000000001 18650800.0 63658.0 53697.0 60777.0 50822.0 64760.0 65256.0 52873.0 40924.0 56824.0 52239.0 False True 62750.22524655255 53572.667895633844 55780.14966600451 54559.61941722206 60950.94412305872 62465.15299916577 55610.505230424074 42825.478440407074 50423.882736752494 61268.441545907895 1.0241851051415167 0.874392534621471 0.9104222052752712 0.8905011787567834 0.9948179288580193 1.0195322652749572 0.907653333874269 0.6989810310144469 0.8229992711495743 1.0 15.902856534233628 -7.537146938447818 24.968402189470748 0.8172574802394369 0.9474530536121774 0.24704913168311304 0.08408115498711696 274.0232310758605 479516.69325103547 0.038518015230867016 0.02225100601307518 2.9030402786328586e-08 7.537146938447818 0.13019557337274046 LFEMAYK ddPTM_PC-9_Lapatinib_30min_R1 1 LFEMAYK 7 0 P38646 P38646 HSPA9 Stress-70 protein, mitochondrial 0 105.39 0.0086471 0.0 16979.0 15756.0 16644.0 15084.0 15273.0 13592.0 13310.0 14782.0 15382.0 13407.0 False True 16736.876346432746 15719.517950045747 15275.594567697965 16193.327678748918 14374.672167873303 13010.701844499523 13999.126673669833 15468.825684344101 13649.51718035912 15724.382086295438 1.064390082521573 0.9996906628048723 0.9714591316762384 1.0298228311853468 0.9141645178160309 0.8274221379954244 0.8902815129295765 0.9837477618803179 0.868047921085264 1.0 13.94071570485416 -6.272060619415961 19.484863354319227 0.907621984852459 1.0119455379281659 0.47439061153437356 0.052468857573689534 32.39010906211344 59419.785824459 0.01624964925200812 0.01873242206691116 5.344897493819933e-07 6.272060619415961 0.10432355307570684 LFGGFNSSDTVT(ph)SPQR ddPTM_PC-9_AZD4547_30min_R2 2 LFGGFNSSDTVTSPQR 16 0 P12931;P12931-2 P12931 SRC Proto-oncogene tyrosine-protein kinase Src 1 LFGGFNSSDTVT(0.718)S(0.282)PQR;LFGGFNSSDTVT(0.774)S(0.226)PQR 161.84 2.4123e-15 6463500.0 52730.0 50308.0 65495.0 92312.0 75564.0 71794.0 55028.0 93636.0 52792.0 67742.0 True False 69497.0431478651 66569.07717344054 64626.49350632723 71030.89460618289 65073.24292958385 67304.70983059057 59925.38539663876 79166.70774122364 55582.47734299591 65370.37319906008 1.063127526230252 1.0183371138287718 0.9886205377707168 1.0865915418577448 0.9954546646296262 1.0295904174455333 0.9167055726324107 1.2110487345720389 0.8502701548565597 1.0 15.996349313085085 LFGGFNSSDTVT(ph)SPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LFGGFNSSDTVTSPQR 16 0 P12931;P12931-2 P12931 SRC Proto-oncogene tyrosine-protein kinase Src 1 LFGGFNS(0.001)S(0.001)DT(0.088)VT(0.716)S(0.194)PQR 126.56 6.7753e-05 8423600.0 33057.0 29743.0 36316.0 36553.0 43105.0 29376.0 34449.0 43119.0 32507.0 26611.0 True False 38652.897194488956 32695.688475360905 37181.911169196945 34505.05391642492 34658.88468183159 27835.47084650752 31185.741330838173 41987.171938356936 32982.353377797954 31435.363647439917 1.2295991746110064 1.0400925798745653 1.182805186738313 1.0976508591856229 1.1025444168721805 0.8854827053599054 0.9920591878814777 1.3356668117238832 1.0492117650588726 1.0 14.940100832003301 -4.750702734915133 24.312154414111045 1.0828984297917565 1.2295996198176964 0.13641852581790648 0.11469125635285998 747.6639269323493 1692856.544188088 0.029533369327587322 0.41064565600623715 1.7754042905371672e-05 4.750702734915133 0.14670119002593984 LFGGFNSSDTVT(ph)SPQR ddPTM_PC-9_Lapatinib_30min_R1 1 LFGGFNSSDTVTSPQR 16 0 P12931;P12931-2 P12931 SRC Proto-oncogene tyrosine-protein kinase Src 1 LFGGFNSSDT(0.002)VT(0.66)S(0.337)PQR 107.46 0.0022108 5477800.0 22243.0 20907.0 23306.0 15888.0 20211.0 17549.0 17195.0 15379.0 21906.0 16020.0 True False 21925.810741133377 20858.59112602225 21389.87064376163 17056.45652081429 19022.22871635484 16798.47017871705 18085.272964218828 16093.564483799737 19438.715599593488 18789.03565469179 1.1669471038370351 1.1101469766392014 1.1384230163201798 0.9077877563426273 1.0124111245488439 0.8940570707002901 0.962543969610424 0.8565402067232243 1.0345776098806576 1.0 14.197603402034066 -5.754627485624392 24.999999997227373 0.9470543958272561 1.135669888915448 0.7128336222147876 0.05399597970029785 77.50042487317172 284427.0193313453 0.013760534989458473 0.02316752884735973 1.759432112853599e-06 5.754627485624392 0.1886154930881918 LFGGFNSSDTVTS(ph)PQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LFGGFNSSDTVTSPQR 16 0 P12931;P12931-2 P12931 SRC Proto-oncogene tyrosine-protein kinase Src 1 LFGGFNSSDT(0.002)VT(0.106)S(0.891)PQR 71.316 0.018226 3119500.0 11575.0 13909.0 12057.0 11804.0 12591.0 13645.0 11071.0 13928.0 13674.0 9834.8 True False 13534.418883329088 15289.79359862134 12344.484606427131 11142.660149084339 10123.883935249776 12929.43217935033 10022.274732901073 13562.404757935836 13873.956381333537 11617.771387766028 1.1649754872592317 1.3160694154063055 1.0625518608006317 0.9591047867251029 0.8714135953742923 1.1129012396444238 0.8626675804152011 1.1673843722056352 1.1942011869800917 1.0 13.504045725728938 -5.385805637180446 5.345886746983904 1.0209768584087515 1.2384353394437648 0.3704640703905 0.11107622314979262 0.22696454623296805 8.841162695210299 0.03016806225373495 0.0644602605253187 4.113337669694503e-06 5.385805637180446 0.2174584810350133 LFGGFNSSDTVTS(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 1 LFGGFNSSDTVTSPQR 16 0 P12931;P12931-2 P12931 SRC Proto-oncogene tyrosine-protein kinase Src 1 LFGGFNSSDTVT(0.337)S(0.663)PQR 178.23 7.2911e-06 4491600.0 25431.0 22600.0 21438.0 16058.0 18061.0 17519.0 15883.0 14451.0 18608.0 17492.0 True False 25068.34927652577 22547.67108853987 19675.45039307313 17238.958887917674 16998.687489292202 16769.753208783644 16705.344023884143 15122.446215969185 16512.171089073105 20515.468893375077 1.2219242663579053 1.0990570678996785 0.9590543845394044 0.8402907570630538 0.8285790384630923 0.8174199330242453 0.8142803906021708 0.7371240840053417 0.8048644257117258 1.0 14.3244245078192 -5.201247613173284 1.217889029101875 0.8156211719789056 1.2724431561831395 0.8083139579338883 0.06399603033669117 0.2991734860321998 0.6137024654239452 0.019296971749449797 0.14332023602676372 6.291473719520219e-06 5.201247613173284 0.4568219842042339 LFIGGLNTETNEK ddPTM_PC-9_Lapatinib_30min_R1 2 LFIGGLNTETNEK 13 0 P38159;P38159-2;H0Y6E7;H3BT71;Q96E39;H3BR27;P38159-3;A0A1B0GUK8;H3BNC1 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 0 ; 156.58 0.00041011 11746600.0 42069.0 35055.0 44847.0 40677.0 42264.0 35072.0 44633.0 36900.0 33002.0 41614.0 False True 41469.08834549025 34973.8323012728 41159.85277442626 43668.522274494164 39778.11461422101 33572.05231682516 46943.87834905376 38614.50871007288 29284.967233533473 48806.92445283045 0.8496558390104694 0.7165752133198504 0.8433199435503314 0.8947198120770281 0.8150096540638337 0.6878542889804692 0.961828242105744 0.7911686536895385 0.6000166484949485 1.0 15.574798223343189 -6.533322534315022 24.95214464663291 0.798803598842265 0.8239023376762534 0.00186400699402689 0.1168399897625392 1696.1547583688973 4052401.484924501 0.03809843803650075 0.03813852069772 2.9287173882064925e-07 6.533322534315022 0.025098738833988388 LFIVDAR ddPTM_PC-9_Lapatinib_30min_R1 2 LFIVDAR 7 0 Q9UNZ2-4;Q9UNZ2;Q9UNZ2-5;Q9UNZ2-6 Q9UNZ2-4 NSFL1C NSFL1 cofactor p47 0 ; 114.59 0.0020778000000000003 3332200.0 61051.0 74645.0 83934.0 74640.0 76391.0 84181.0 72599.0 72173.0 80149.0 68213.0 False True 60180.401544617744 74472.16408867529 77033.27051460948 80129.27459174076 71897.8315704846 80580.7748654954 76357.82099036478 75526.42106049025 71121.7756136136 80003.52616189064 0.7522218636068624 0.9308610215251963 0.9628734408372112 1.0015717860934736 0.8986832833467389 1.007215290766518 0.954430693915308 0.9440386528421163 0.8889830114449653 1.0 16.28777596785148 -4.75862392554064 3.6918942239494767 0.9560716298398793 0.7246859731898325 0.7188209376514016 0.038223538253044954 0.15051415988480818 3.462536802750873 0.009345617834720878 0.09941983221803728 1.7433158328767994e-05 4.75862392554064 -0.23138565665004673 LFPADT(ph)SPSTATK ddPTM_PC-9_AZD4547_30min_R2 4 LFPADTSPSTATK 13 0 Q6NZY4-2;Q6NZY4 Q6NZY4-2 ZCCHC8 Zinc finger CCHC domain-containing protein 8 1 LFPADT(0.647)S(0.339)PS(0.012)T(0.001)ATK;LFPADT(0.608)S(0.384)PS(0.003)T(0.004)ATK;LFPADT(0.491)S(0.491)PS(0.014)T(0.004)AT(0.001)K;LFPADT(0.498)S(0.498)PS(0.003)T(0.001)ATK 147.52 0.00026958 129685000.0 231053.0 192374.0 254290.0 332395.0 289252.0 254936.0 241940.0 281710.0 220026.0 249690.0 True False 304523.04779904615 254555.1334213927 250917.94844986586 255766.46820155715 249094.3526529566 238994.81161895822 263472.19130011543 238178.19255179682 231656.12516801825 240948.4290997216 1.2638515591774737 1.0564714381932727 1.0413761541728839 1.0614987993787781 1.0338077470920701 0.9918919683848413 1.0934795976240703 0.988502782283016 0.9614344697476424 1.0 17.878364869673547 LFPADT(ph)SPSTATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LFPADTSPSTATK 13 0 Q6NZY4-2;Q6NZY4 Q6NZY4-2 ZCCHC8 Zinc finger CCHC domain-containing protein 8 1 LFPADT(0.5)S(0.5)PSTATK;LFPADT(0.496)S(0.496)PS(0.006)T(0.002)ATK;LFPADT(0.498)S(0.498)PS(0.001)T(0.003)ATK;LFPADT(0.487)S(0.444)PS(0.024)T(0.039)AT(0.005)K;LFPADT(0.494)S(0.494)PS(0.009)T(0.003)ATK 173.72 0.00010966 110215300.0 338697.0 311801.0 322913.0 341613.0 373522.0 340625.0 364395.0 328446.0 324135.0 237383.0 True False 396031.7125293232 342754.54265897867 330612.4705743727 322473.5311342898 300333.0454501125 322762.0253639578 329876.8676086613 319824.6405173025 328874.8611718262 280418.65877720556 1.4122873073291922 1.222295777868688 1.1789959770011111 1.149971733480464 1.0710166247843338 1.1510005317456222 1.1763727458334026 1.1405255338996727 1.172799494177452 1.0 18.097222822464893 -3.908092141845119 0.9815830346803752 1.1296634472037697 2.55043646278165 0.7465179012890524 0.05080677715271785 4.45107096925384 0.966361226158248 0.015757844203464693 10.063469877819285 0.00012356852371659917 3.908092141845119 1.4207730155778802 LFPADT(ph)SPSTATK ddPTM_PC-9_Lapatinib_30min_R1 4 LFPADTSPSTATK 13 0 Q6NZY4-2;Q6NZY4 Q6NZY4-2 ZCCHC8 Zinc finger CCHC domain-containing protein 8 1 LFPADT(0.496)S(0.496)PS(0.007)T(0.001)ATK;LFPADT(0.499)S(0.499)PS(0.001)TATK;LFPADT(0.498)S(0.498)PS(0.004)T(0.001)ATK;LFPADT(0.496)S(0.496)PS(0.008)TATK 158.81 0.00062279 78814000.0 255488.0 215169.0 255494.0 206731.0 243429.0 226450.0 204223.0 200250.0 232722.0 184322.0 True False 251844.6942692392 214670.78940044416 234488.26955536075 221934.6873743994 229110.9848198282 216765.26138073244 214796.66766918634 209554.346048566 206510.39768869666 216181.81210637302 1.1649670794012872 0.9930104078081029 1.084680840032833 1.0266112824754918 1.059806940220731 1.0026988823373926 0.9935926874527949 0.9693430913857547 0.9552625897459056 1.0 17.721885625225802 -1.5228787452803394 0.2688661238101576 0.9700727799562663 2.0155831596262392 0.5672582641341698 0.03917260997258591 39.23124549190705 0.5471905700237083 0.045062963942600634 19.00561453824475 0.029999999999999874 1.5228787452803394 1.045510379669973 LFPADTS(ph)PSTATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LFPADTSPSTATK 13 0 Q6NZY4-2;Q6NZY4 Q6NZY4-2 ZCCHC8 Zinc finger CCHC domain-containing protein 8 1 LFPADT(0.227)S(0.764)PS(0.008)T(0.001)ATK 133.04 4.8778999999999995e-05 9007300.0 35903.0 34390.0 36967.0 37677.0 40699.0 33875.0 38334.0 36648.0 30957.0 24594.0 True False 41980.66878342674 37804.01192440779 37848.43347812822 35566.07984048211 32724.323110216068 32098.535366470664 34702.726005873905 35686.028831765696 31409.687560109895 29052.697514003128 1.4449835084398774 1.3012220949943325 1.302751094279133 1.2241919988097352 1.126378130445314 1.1048383838023808 1.1944751770174702 1.2283206684875083 1.081128096451998 1.0 14.826384502194733 -1.5228787452803376 0.272003939924963 1.0802247019771898 3.618527569697794 0.7870497904911962 0.05667538217717369 25.94994242507553 0.3631389469519747 0.0697804056035699 30.998533642297357 0.029999999999999995 1.5228787452803376 2.5383028677206045 LFPDT(ph)PLALDANK ddPTM_PC-9_AZD4547_30min_R2 7 LFPDTPLALDANK 13 0 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 LFPDT(1)PLALDANK;LFPDT(1)PLALDANK;LFPDT(1)PLALDANK;LFPDT(1)PLALDANK;LFPDT(1)PLALDANK;LFPDT(1)PLALDANK;LFPDT(1)PLALDANK 121.45 0.00072627 19481950.0 53557.69999999999 46549.799999999996 61733.7 75052.4 70247.5 71744.6 51113.5 64995.1 53087.80000000001 61331.700000000004 True False 70587.9345306355 61596.112519047034 60915.070801916954 57750.22872802095 60494.84718511389 67258.39882040006 55662.50248003002 54951.60073381608 55893.91272710825 59184.49585091661 1.1926761141709088 1.0407474395693965 1.0292403428654624 0.9757661681108424 1.0221401114490862 1.1364192235382269 0.9404912837348763 0.9284796625156185 0.9444012646133337 1.0 15.852931672151938 -7.289116636998319 24.78624446994982 0.9473829992753359 1.057221014121349 0.4490200834161069 0.060599153300522644 672.8481077954212 602563.4192338205 0.026158551890097585 0.017641609219094842 5.139056151564848e-08 7.289116636998319 0.10983801484601308 LFPDT(ph)PLALDANK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 LFPDTPLALDANK 13 0 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 LFPDT(1)PLALDANK;LFPDT(1)PLALDANK;LFPDT(1)PLALDANK;LFPDT(1)PLALDANK;LFPDT(1)PLALDANK;LFPDT(1)PLALDANK;LFPDT(1)PLALDANK 144.8 0.00022989 4236040.0 76106.50000000001 88593.29999999999 84475.6 89392.40000000001 98900.5 74424.0 98394.3 82250.0 75487.0 67718.5 True False 88989.82727810659 97388.25733127781 86489.81867949724 84384.03364207101 79521.65698817985 70521.07442403579 89073.67959095721 80091.0246510788 76590.85456762656 79995.32799064914 1.112437807474317 1.217424314363231 1.0811858748751835 1.0548620245914222 0.9940787666684152 0.8815649137944553 1.1134860226008356 1.0011962781181527 0.9574415967964963 1.0 16.287628123530126 -5.714286296368448 1.8736864710777572 0.993779610823445 1.1640014228065954 0.5535970792897382 0.060190419170408745 0.25490382576258347 1.8167062859543712 0.018573476480467976 0.039719027192360964 1.9306951411804206e-06 5.714286296368448 0.17022181198315034 LFPDT(ph)PLALDANK ddPTM_PC-9_Lapatinib_30min_R1 3 LFPDTPLALDANK 13 0 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 LFPDT(1)PLALDANK;LFPDT(1)PLALDANK;LFPDT(1)PLALDANK 117.2 0.00064127 5433400.0 64700.8 109762.2 116943.6 97735.7 116462.1 118601.6 91845.4 92396.2 112414.4 88819.0 True False 63778.154727326466 109508.05236966962 107328.94862335018 104923.50941473762 109612.0282512983 113529.28604183311 96600.70540900636 96689.26476091155 99753.10649588885 104171.24580612194 0.6122433713236667 1.0512310909046847 1.0303126145107757 1.0072214131912731 1.0522292154910238 1.0898332372171864 0.9273260069174418 0.9281761393241331 0.9575877270542017 1.0 16.66859758259357 -4.757352066346147 24.999995010751547 1.0052141054873365 0.6122427994175688 0.8400435195453319 0.05139964923173967 50.20266144204537 307022.56628096127 0.014259017965007533 0.10656568707896787 1.7484287279693775e-05 4.757352066346147 -0.3929713060697677 LFPDT(ph)PLALDANKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LFPDTPLALDANKK 14 1 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 LFPDT(1)PLALDANKK 89.23100000000001 0.0045889 6721700.0 55979.0 56405.0 48581.0 55858.0 58480.0 54648.0 54248.0 55738.0 46525.0 36495.0 True False 65455.13906435243 62004.51563234147 49739.355284468504 52728.457354079364 47021.2638021926 51782.16267769416 49109.23671849135 54274.93655929264 47205.34010834745 43111.25460573893 1.518284254609447 1.4382442867734933 1.1537440916379 1.2230787026796524 1.0906957877290162 1.2011286414940234 1.1391279879837681 1.2589505236079956 1.094965584742308 1.0 15.395776927385745 -5.191683777124195 3.2099683050090206 1.1551199872847364 1.5074567858388401 0.7798367253574876 0.0710828839033843 0.10634639459813046 2.1181426532665015 0.017452543400024216 0.05631048275903988 6.43155847985304e-06 5.191683777124195 0.3523367985541037 LFPDT(ph)PLALDANKK ddPTM_PC-9_Lapatinib_30min_R1 1 LFPDTPLALDANKK 14 1 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 LFPDT(1)PLALDANKK 64.58800000000001 0.034714 3444600.0 6302.2 6997.9 5870.3 7602.8 9112.4 7546.4 7198.7 4145.5 7941.1 6802.5 True False 6212.329472318068 6981.696792499691 5387.6665940133025 8161.935274197308 8576.4265476677 7223.6580635176 7571.41346249038 4338.115063891789 7046.689694509809 7978.303061238505 0.778652982298933 0.875085433445028 0.675289789402529 1.0230164499329382 1.0749687598776607 0.9054128438179737 0.9490004834831429 0.5437390671417245 0.8832316396634753 1.0 12.961866210875034 -10.877824459931897 3.9237861651807324 1.0004180873393795 0.8579913286491054 0.07628465994330236 0.1497338151200829 229010789.10508633 537.846905211005 865041.1895910274 0.038043290539984315 1.3248769368680121e-11 10.877824459931897 -0.1424267586902741 LFPDTPLALDANK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LFPDTPLALDANK 13 0 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 0 90.146 0.036357 0.0 7692.9 10236.0 9779.0 12382.0 13116.0 7862.6 15402.0 11844.0 9775.9 7320.4 False True 8995.156028299118 11252.162432632695 10012.168447064023 11688.276682985623 10546.013953993812 7450.271414683756 13943.011059176435 11533.107549755317 9918.85404331421 8647.53057174548 1.0401993902963989 1.3011994972758423 1.1578066552059723 1.3516317272326657 1.219540522753553 0.8615490113474025 1.6123690969920534 1.3336879764771266 1.1470157822537905 1.0 13.07807249365088 -7.261730241995214 24.999980344177548 1.3010755187582652 1.1739072319397432 0.06948710067262076 0.19440282111213592 70.82179579066089 6086793.249943405 0.07680502150686012 0.055476239345007096 5.4735584235075334e-08 7.261730241995214 -0.127168286818522 LFPGS(ph)PAIYK ddPTM_PC-9_AZD4547_30min_R2 2 LFPGSPAIYK 10 0 P49792;J3KQ37;F8VYC4;A0A286YES2;A0A1W2PNU4;J3KNE0;P0DJD0;P0DJD1;Q7Z3J3;A6NKT7;H0YBN8;C9J6W1;Q7Z3J3-2;Q99666;O14715;F8W705;Q99666-2;C9J1W9;C9JF75 P49792;Q99666 RANBP2;RGPD8;RGPD1;RGPD3;RGPD2;RGPD4;RGPD5;RGPD6 E3 SUMO-protein ligase RanBP2;RANBP2-like and GRIP domain-containing protein 1;RANBP2-like and GRIP domain-containing protein 2;RanBP2-like and GRIP domain-containing protein 4;RanBP2-like and GRIP domain-containing protein 3;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8 1 LFPGS(1)PAIYK;LFPGS(0.998)PAIY(0.002)K 89.805 0.009115 21094000.0 213921.0 197396.0 248970.0 306450.0 288690.0 225150.0 213208.0 282950.0 209300.0 239320.0 True False 281943.42816678254 261200.39671083027 245668.49512589164 235802.68710530284 248610.37665213042 211071.33490761754 232183.0989613753 239226.57904416273 220363.17070558158 230941.47964333906 1.2208436033328 1.1310241759696977 1.0637694688078412 1.0210495207247798 1.0765081138134163 0.9139602605542818 1.005376337416534 1.0358753196420971 0.9541948507730427 1.0 17.817167794804085 -3.9798117870850827 0.5836915177130011 0.9885429400754323 1.703247198832546 0.7771781729432827 0.039284406240619435 3.9749178019173894 0.5125211292628286 0.01908400212857322 2.3597084160327144 0.00010475824470440412 3.9798117870850827 0.7147042587571136 LFPGS(ph)PAIYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LFPGSPAIYK 10 0 P49792;J3KQ37;F8VYC4;A0A286YES2;A0A1W2PNU4;J3KNE0;P0DJD0;P0DJD1;Q7Z3J3;A6NKT7;H0YBN8;C9J6W1;Q7Z3J3-2;Q99666;O14715;F8W705;Q99666-2;C9J1W9;C9JF75 P49792;Q99666 RANBP2;RGPD8;RGPD1;RGPD3;RGPD2;RGPD4;RGPD5;RGPD6 E3 SUMO-protein ligase RanBP2;RANBP2-like and GRIP domain-containing protein 1;RANBP2-like and GRIP domain-containing protein 2;RanBP2-like and GRIP domain-containing protein 4;RanBP2-like and GRIP domain-containing protein 3;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8 1 LFPGS(1)PAIYK 70.41199999999999 0.035844 9188200.0 51805.0 65501.0 66752.0 67188.0 66564.0 62024.0 62998.0 66424.0 54723.0 49357.0 True False 60574.563304610245 72003.50639897176 68343.62083836974 63423.67418643503 53521.26203367212 58771.352252988254 57030.373373977236 64680.44038204548 55523.22034925517 58305.03339020295 1.0389251113058902 1.2349449474986594 1.1721735991639717 1.0877907188900122 0.9179526864427686 1.0079979177726301 0.9781380793027743 1.109345739486598 0.9522886296568829 1.0 15.83133281415244 -6.013907874415777 5.176266539398617 0.999344761749992 1.1545063826981588 0.5398151340734041 0.06457563303460834 0.13397783872128674 10.833529066980375 0.018612978121393526 0.025953699434735356 9.684832759218354e-07 6.013907874415777 0.15516162094816677 LFPGS(ph)PAIYK ddPTM_PC-9_Lapatinib_30min_R1 1 LFPGSPAIYK 10 0 P49792;J3KQ37;F8VYC4;A0A286YES2;A0A1W2PNU4;J3KNE0;P0DJD0;P0DJD1;Q7Z3J3;A6NKT7;H0YBN8;C9J6W1;Q7Z3J3-2;Q99666;O14715;F8W705;Q99666-2;C9J1W9;C9JF75 P49792;Q99666 RANBP2;RGPD8;RGPD1;RGPD3;RGPD2;RGPD4;RGPD5;RGPD6 E3 SUMO-protein ligase RanBP2;RANBP2-like and GRIP domain-containing protein 1;RANBP2-like and GRIP domain-containing protein 2;RanBP2-like and GRIP domain-containing protein 4;RanBP2-like and GRIP domain-containing protein 3;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8 1 LFPGS(1)PAIYK 73.632 0.02745 8114000.0 103900.0 92166.0 88939.0 75526.0 78742.0 90341.0 69940.0 67923.0 101150.0 61806.0 True False 102418.36694707334 91952.59528966235 81626.77873446827 81080.43398735013 74110.55037272835 86477.32602515694 73561.15098095179 71078.95054510236 89757.42184327947 72489.08474868172 1.4128798466990702 1.2685026388243175 1.1260561368303486 1.1185192124918455 1.0223684107706452 1.1929703116679178 1.0147893470580696 0.9805469442955684 1.2382198251566667 1.0 16.14547615309784 -4.8305199582724745 1.1481386516781626 1.075770621336852 1.5628232477943227 0.6495296269926746 0.07910798467253355 0.8968138477981734 1.0482515350017376 0.023870740266266875 0.5185875473614268 1.4773385880178106e-05 4.8305199582724745 0.4870526264574706 LFPIGY(ph)QCS(ph)RVYWSTTDARKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LFPIGYQCSRVYWSTTDARKR 21 3 Q03164-2;Q03164;Q03164-3 Q03164-2 KMT2A Histone-lysine N-methyltransferase 2A;MLL cleavage product N320;MLL cleavage product C180 2 LFPIGY(0.988)QCS(0.923)RVY(0.061)WS(0.023)T(0.003)T(0.001)DARKR 49.535 0.018791 4936600.0 9620.7 10983.0 7275.8 6614.5 5832.1 5262.7 8343.9 5603.3 7313.8 6817.5 True False 11249.294492513533 12073.319655881678 7449.28266562516 6243.911009498336 4689.341871080152 4986.714747546131 7553.505387395296 5456.219312187097 7420.750488649788 8053.458782699693 1.396827722851091 1.4991471343737903 0.9249792997795663 0.7753079984604133 0.582276758050059 0.6192016228180752 0.9379206613215195 0.6775001225446211 0.9214364521975231 1.0 12.975392806641423 -5.3644776068675295 3.38133230148903 0.768283330539795 1.4553801295248145 0.7875190755065944 0.1345480753144659 0.09843522018669625 2.0865893632585024 0.03629493309549648 0.0872943494284062 4.320384438502595e-06 5.3644776068675295 0.6870967989850195 LFPSPGLPTRTS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 1 LFPSPGLPTRTSPVR 15 1 M0QYT1;M0R2C2;A0A384DVU0;Q8IY17-5;Q8IY17-2;Q8IY17-3;Q8IY17 M0QYT1 PNPLA6 Neuropathy target esterase 1 LFPSPGLPT(0.274)RT(0.274)S(0.452)PVR 66.977 0.014518999999999999 10319000.0 44946.0 26968.0 52602.0 68103.0 61157.0 43414.0 37535.0 38765.0 39273.0 55953.0 True False 59237.89306512319 35684.8786120168 51904.463110463745 52402.905530861266 52666.40619666188 40699.315716985635 40875.54228507007 32774.759981081326 41348.89060258143 53994.102500767694 1.0971178391988448 0.6609032646020818 0.9612987475757331 0.9705301709592487 0.9754103458968146 0.7537733536066641 0.7570371650216595 0.6070062925967763 0.7658038320387588 1.0 15.720514217241522 -6.773770440645312 24.309946681216747 0.7509315135065628 0.9215840625108241 0.23238520038613808 0.13735099719529512 220.177302847768 434062.9189367334 0.04679294007547069 0.041580038113795896 1.6835637239465372e-07 6.773770440645312 0.1706525490042613 LFPSPGLPTRTS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 1 LFPSPGLPTRTSPVR 15 1 M0QYT1;M0R2C2;A0A384DVU0;Q8IY17-5;Q8IY17-2;Q8IY17-3;Q8IY17 M0QYT1 PNPLA6 Neuropathy target esterase 1 LFPSPGLPT(0.213)RT(0.213)S(0.574)PVR 74.993 0.0072795 8439900.0 54115.0 49302.0 33909.0 23714.0 26209.0 26936.0 29166.0 20579.0 39190.0 19902.0 True False 53343.31017652437 49187.84424810584 31121.132912525256 25458.006667584992 24667.438148876547 25784.01007088281 30676.07276966597 21535.175467333047 34776.0095110047 23342.034182251922 2.2852896949779926 2.107264682420255 1.3332656729715595 1.0906507320146908 1.0567818535555222 1.1046170984741184 1.3141987767711554 0.9225920628506012 1.4898448541150102 1.0 14.51064267224717 -5.270850290261368 2.7312492251222054 1.1396369246797253 2.2721170700599824 0.8829626965874832 0.15237338681098758 0.07808261260506658 1.1366271287098688 0.0387491505452616 0.11925111761270481 5.3598138886072365e-06 5.270850290261368 1.132480145380257 LFQDEEIY(ph)S(ph)DLYLTVCEWPS(ph)DASK ddPTM_PC-9_AZD4547_30min_R2 1 LFQDEEIYSDLYLTVCEWPSDASK 24 0 Q66K64 Q66K64 DCAF15 DDB1- and CUL4-associated factor 15 3 LFQDEEIY(0.798)S(0.808)DLY(0.406)LT(0.234)VCEWPS(0.409)DAS(0.345)K 48.229 0.0087477 3051300.0 8946.6 7453.7 11670.0 11811.0 10485.0 11971.0 9887.4 9999.5 8387.4 9255.5 True False 11791.432699159686 9862.96275995215 11515.248174957458 9088.156428130957 9029.338734274084 11222.451477588675 10767.35944556818 8454.307040650665 8830.740840783526 8931.467762154949 1.3202121995136324 1.1042936080163888 1.289289563777041 1.0175434396841176 1.0109579942205962 1.2565069679970458 1.2055531892744888 0.9465753295862362 0.9887222431907295 1.0 13.124681566299637 -1.5228787452884438 0.1634406744883781 0.9630813429443777 2.1116221751845075 0.350337637439341 0.10774041628581621 80.82387145218303 0.8502833874538102 0.32577252997292 22.460944612425745 0.02999999999944004 1.5228787452884438 1.1485408322401298 LFQDEEIY(ph)S(ph)DLYLTVCEWPS(ph)DASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LFQDEEIYSDLYLTVCEWPSDASK 24 0 Q66K64 Q66K64 DCAF15 DDB1- and CUL4-associated factor 15 3 LFQDEEIY(0.925)S(0.929)DLY(0.177)LT(0.149)VCEWPS(0.462)DAS(0.358)K 51.025 0.0078039 2745300.0 8667.5 11814.0 9991.0 11307.0 12144.0 9688.0 9501.9 7033.2 8714.1 7117.5 True False 10134.73655907169 12986.81584399401 10229.223331078494 10673.505447788599 9764.470376433424 9179.944225250718 8601.81124420131 6848.585952291378 8841.527227042461 8407.846407901001 1.2053903065531621 1.5446066940269119 1.2166282344865285 1.2694696037452013 1.161352134984005 1.0918306281884695 1.0230695028060974 0.8145469862360523 1.0515804878088546 1.0 13.037520599468426 -6.5733344220051295 0.9174835157754622 0.9461889265574664 1.357662503232508 0.6791418139134267 0.10450183489639274 0.30306448877596087 0.5575913007721324 0.056214965219609066 0.06351223630355927 2.67094889212422e-07 6.5733344220051295 0.4114735766750416 LFQDEEIY(ph)S(ph)DLYLTVCEWPS(ph)DASK ddPTM_PC-9_Lapatinib_30min_R1 1 LFQDEEIYSDLYLTVCEWPSDASK 24 0 Q66K64 Q66K64 DCAF15 DDB1- and CUL4-associated factor 15 3 LFQDEEIY(0.796)S(0.803)DLY(0.386)LT(0.229)VCEWPS(0.418)DAS(0.368)K 44.105 0.019121 2534300.0 6398.4 8411.3 8574.1 7098.1 9147.1 7780.4 7623.8 8229.3 6751.0 6088.7 True False 6307.157642677146 8391.82415163873 7869.170594983126 7620.117952567468 8609.085561890519 7447.650428998247 8018.523060460108 8611.66332053666 5990.631288818384 7141.123682317224 0.8832164128867932 1.175140569602299 1.1019513097733742 1.067075476011755 1.2055645504653907 1.0429241615629823 1.122865730545389 1.205925524278591 0.8388919664915373 1.0 12.801935390198594 -8.265413458893933 24.999894385677784 0.9194459816109383 1.1043171003189183 0.36041910194194704 0.09641597105910539 363.26767374544033 2285174.309667565 0.0769458518475501 0.02277347481262766 5.427333900930455e-09 8.265413458893933 0.18487111870798 LFQDEEIYS(ph)DLYLT(ph)VCEWPS(ph)DASK ddPTM_PC-9_AZD4547_30min_R2 1 LFQDEEIYSDLYLTVCEWPSDASK 24 0 Q66K64 Q66K64 DCAF15 DDB1- and CUL4-associated factor 15 3 LFQDEEIY(0.119)S(0.623)DLY(0.601)LT(0.625)VCEWPS(0.547)DAS(0.485)K 43.799 0.03565 3064300.0 8940.3 8964.4 10225.0 10039.0 11817.0 9928.9 9831.1 11677.0 9682.1 8434.2 True False 11783.129430207831 11861.966991603513 10089.40981910368 7724.663651003876 10176.413526267694 9308.044313409926 10706.048854635725 9872.58796076582 10193.876039601095 8138.921225170684 1.4477507650236194 1.4574372528534643 1.239649523563498 0.9491016606862268 1.2503393563751173 1.143645952073301 1.3154137456848534 1.2130094010780623 1.252484912628862 1.0 12.990621869542451 -5.328190596310561 4.325436392685238 1.174016293746164 1.4546605536864985 0.527827292028569 0.10797270779943767 0.16283235687628184 5.9828731680284895 0.02861638290331164 0.0653089014465997 4.696879341367338e-06 5.328190596310561 0.2806442599403345 LFQECCPHSTDR ddPTM_PC-9_AZD4547_30min_R2 4 LFQECCPHSTDR 12 0 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 ;;; 135.58 5.1053999999999996e-05 54951800.0 63919.0 59863.3 155139.0 248561.0 182642.0 162444.0 113315.0 187606.0 125273.0 152039.0 False True 84243.91240220745 79212.94103436472 153081.75549397818 191259.10167916853 157285.31093040394 152286.35100036886 123399.81547975774 158615.8034570034 131894.6750301018 146716.16088706974 0.574196543126913 0.5399060373133431 1.043387139960731 1.303599416197813 1.0720380766469857 1.037965757007414 0.8410785474051558 1.0811065563465299 0.898978505385127 1.0 17.162668268062227 -5.2625633814393025 24.79839268896182 1.0417946675484182 0.5570512476155615 0.7312729171765762 0.11577441327384694 43.356426117090024 956585.5442645178 0.03210699361071039 0.07350495856952384 5.463068154148374e-06 5.2625633814393025 -0.48474341993285675 LFQECCPHSTDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LFQECCPHSTDR 12 0 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 ;;;;; 133.88 4.675e-05 35168600.0 90364.0 92476.0 151174.0 171197.0 201268.0 179229.0 193834.0 173245.0 161949.0 121810.0 False True 105660.8404296458 101656.40612740708 154778.56149058757 161605.38711816285 161830.98021442746 169829.915725378 175472.6402833664 168697.50231825095 164317.19774759328 143893.18875257068 0.7343004998751766 0.7064712861580181 1.0756489784706533 1.1230926808915807 1.124660462509462 1.180249858924222 1.2194645334123333 1.1723800395328798 1.1419386780714296 1.0 17.13463877752644 -5.321680837968145 3.514491537486222 1.1468150444045604 0.7118908790873195 0.8958700072389298 0.05596801464376748 0.062279057634591684 1.5268571772109207 0.01497666557125816 0.03715129481296281 4.767812435450385e-06 5.321680837968145 -0.4349241653172409 LFQECCPHSTDR ddPTM_PC-9_Lapatinib_30min_R1 4 LFQECCPHSTDR 12 0 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 ;;; 143.76 5.1053999999999996e-05 46836900.0 116955.0 97733.0 186650.0 137943.0 156782.0 180209.0 143858.0 110995.0 196183.0 113437.0 False True 115287.20025307979 97506.7052431975 171304.35748983585 148087.78838435837 147560.3910052715 172501.88115769695 151306.2633374001 116152.23290716912 174086.8046414248 133044.43430469834 0.8665315528272988 0.732888269642965 1.2875725195502326 1.1130701495201802 1.1091060800584014 1.2965734497591472 1.137261127292845 0.8730333855316134 1.3084861877253071 1.0 17.02154863328277 -5.25295894992522 24.998221800062474 1.1394411757731235 0.7997098797567226 0.5135061841089563 0.1327318046292057 480.87107482847233 1417482.3066809566 0.03302531981245389 0.0844306663206134 5.585229845550479e-06 5.25295894992522 -0.33973129601640095 LFQLGPPS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 3 LFQLGPPSPVK 11 0 Q9NZH5-2;Q9NZH5;O95997 Q9NZH5-2 PTTG2;PTTG1 Securin-2;Securin 1 LFQLGPPS(1)PVK;LFQLGPPS(1)PVK;LFQLGPPS(1)PVK 87.49799999999999 0.01034 110603200.0 75511.0 83707.0 95579.0 87233.0 81305.0 95512.0 97112.0 112125.0 92872.0 89019.0 True False 99521.92727362874 110763.65077039787 94311.56000979088 67122.77958641513 70017.2041764572 89539.6195411787 105754.7798691279 94798.65762617684 97781.02431805425 85902.47190527462 1.1585455583091067 1.2894116818027994 1.0978911074152677 0.7813835632161084 0.8150778740530978 1.0423404304350496 1.231102871937662 1.1035614636411408 1.138279518031544 1.0 16.390412026095618 -5.516530976243379 24.98357303135472 1.0156382542860556 1.2163968519606627 0.2820821363545679 0.13188312892328552 393.8810513179552 1550236.260580091 0.04073322770946709 0.07392512819433703 3.044170855464766e-06 5.516530976243379 0.20075859767460713 LFQLGPPS(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LFQLGPPSPVK 11 0 Q9NZH5-2;Q9NZH5;O95997 Q9NZH5-2 PTTG2;PTTG1 Securin-2;Securin 1 LFQLGPPS(1)PVK;LFQLGPPS(1)PVK;LFQLGPPS(1)PVK;LFQLGPPS(1)PVK 93.649 0.0069867 221830000.0 105025.0 130225.0 115152.0 116462.0 142483.0 104586.0 148430.0 119898.0 114269.0 95584.0 True False 122803.65816169664 143152.87737295765 117897.6603963916 109937.01171489847 114564.47897277353 99101.32604686946 134369.63585985967 116750.8045424318 115939.96794929098 112912.6225574721 1.0875990246280043 1.267819966718897 1.0441495177953388 0.9736467830152554 1.0146295106595424 0.8776815541276376 1.190032016052643 1.0339924970125114 1.026811399144307 1.0 16.784847249149585 -5.406812805070056 6.59818608214478 1.0187149512347449 1.1764085015900207 0.37125079895890645 0.08261176338787932 0.24009096019222168 12.140601541812995 0.02150166826941626 0.045186320420247124 3.91910766888375e-06 5.406812805070056 0.15769355035527588 LFQLGPPS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 2 LFQLGPPSPVK 11 0 Q9NZH5-2;Q9NZH5;O95997 Q9NZH5-2 PTTG2;PTTG1 Securin-2;Securin 1 LFQLGPPS(1)PVK;LFQLGPPS(1)PVK 118.08 0.0010989 194718000.0 72929.0 139294.0 120736.0 134098.0 148640.0 130324.0 124362.0 156298.0 139647.0 118250.0 True False 71889.01908645942 138971.47330119752 110809.55213443757 143960.01425781462 139897.2874374837 124750.3463200822 130800.85585206056 163560.1756739018 123918.48431189763 138689.35494177937 0.5183456157585983 1.0020341745733592 0.7989766206710998 1.0380033443680508 1.008709626605527 0.8994947476138406 0.9431210917879722 1.1793275391796507 0.8934967241279446 1.0 17.081497532739476 -4.502845389318696 2.3733307056108788 0.9772886665746847 4.795043995201195e-07 0.6486928725596477 0.09902730386373886 1.3405357516366467 3.926566402769606 0.025480960532959035 3.7268585193086636 3.141626927354486e-05 4.502845389318696 -0.9772881870702852 LFRPPS(ph)PAPAAPGAR ddPTM_PC-9_AZD4547_30min_R2 1 LFRPPSPAPAAPGAR 15 1 Q86U90 Q86U90 YRDC YrdC domain-containing protein, mitochondrial 1 LFRPPS(1)PAPAAPGAR 92.773 0.016825 23514000.0 10748.0 7875.5 13947.0 17198.0 15358.0 13742.0 10073.0 11997.0 9910.7 11489.0 True False 14165.64042771201 10421.101361203586 13762.053667192084 13233.266806451302 13225.806798376858 12882.710567623719 10969.477486013335 10143.139313634278 10434.55936890495 11086.77360697944 1.277706294894877 0.9399579833255733 1.24130375121293 1.1936084631619595 1.192935588587363 1.1619891434883893 0.9894201753256454 0.9148864830475913 0.9411718628705558 1.0 13.436551963404902 -7.322387523436046 3.7401102614887995 0.9473214723876439 1.164131137048725 0.5789791113531135 0.08655958050393091 0.17247571459342123 4.857648272613104 0.037526468644394316 0.024902753065847973 4.7600605433943714e-08 7.322387523436046 0.2168096646610812 LFRPPS(ph)PAPAAPGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LFRPPSPAPAAPGAR 15 1 Q86U90 Q86U90 YRDC YrdC domain-containing protein, mitochondrial 1 LFRPPS(1)PAPAAPGAR;LFRPPS(1)PAPAAPGAR 65.105 0.016319 111095000.0 55473.0 53198.0 69609.0 77901.0 74077.0 70142.0 78081.0 71610.0 67432.0 58660.0 True False 64863.48325830792 58479.145866666106 71268.74255360266 73536.45952844968 59562.14361619397 66463.63004206607 70684.60242251359 69730.31337706663 68418.06543118945 69294.59364769554 0.9360540244753282 0.843920756126851 1.0284892197498696 1.0612149614776651 0.8595496485485887 0.9591459671439517 1.0200594115882269 1.0062879325274112 0.9873506983681513 1.0 16.080455177483117 -5.263521314066125 24.99282624450769 0.9883054088428269 0.8899873895783286 0.348091394964796 0.054838396838176685 199.17647500862878 2391068.8026980385 0.014838900299049529 0.03355422759335178 5.451031427596924e-06 5.263521314066125 -0.09831801926449835 LFRPPS(ph)PAPAAPGAR ddPTM_PC-9_Lapatinib_30min_R1 4 LFRPPSPAPAAPGAR 15 1 Q86U90 Q86U90 YRDC YrdC domain-containing protein, mitochondrial 1 LFRPPS(1)PAPAAPGAR;LFRPPS(1)PAPAAPGAR;LFRPPS(1)PAPAAPGAR;LFRPPS(1)PAPAAPGAR 115.56 0.00076319 60173300.0 84412.0 75319.0 76400.0 63694.0 74637.0 70828.0 54805.0 56063.2 77973.0 45517.8 True False 83208.26940073514 75144.60348308542 70118.68691252857 68378.26923695536 70246.99840198792 67798.85154813225 57642.53473707552 58668.100940773926 69190.85964790932 53385.49108134395 1.5586307761775564 1.4075847568506379 1.3134408898793888 1.2808399408140083 1.315844379795101 1.2699864733814388 1.0797415846422593 1.0989521638263253 1.2960611253436367 1.0 15.70416008421245 -1.522878745281098 0.18874944166802274 1.0268459581922038 3.2681048155339303 0.7667529846407783 0.07555694368633344 26.963392291431116 0.3137683436225298 0.16034014758960388 17.566629313799243 0.02999999999994748 1.522878745281098 2.2412588573417267 LFS(ph)DEDDR ddPTM_PC-9_AZD4547_30min_R2 2 LFSDEDDR 8 0 H0Y322;Q5TKA1;Q5TKA1-2;B1B047 H0Y322 LIN9 Protein lin-9 homolog 1 LFS(1)DEDDR;LFS(1)DEDDR 147.75 0.0010228 4856100.0 29274.0 40957.0 32375.0 26188.0 26179.0 35683.0 36083.0 30155.0 31879.0 25238.0 True False 38582.5230629737 54195.54929221199 31945.686346550803 20150.761200566736 22544.497732433112 33451.73636912511 39294.31709796677 25495.237642964225 33564.05885773162 24354.425301849347 1.5842099571137875 2.2252854920824867 1.311699452999411 0.827396292493775 0.9256838317068069 1.37353831817107 1.613436433459301 1.0468420965379237 1.3781503132074706 1.0 14.571896319453153 -5.397498366525497 5.945586560844563 1.1777275705752575 1.8970877047107433 0.542659844908723 0.2667782067260852 0.16874388864800471 7.398899733841652 0.0724288746806399 0.15316600582971096 4.004069743440481e-06 5.397498366525497 0.7193601341354858 LFS(ph)DEDDR ddPTM_PC-9_Lapatinib_30min_R1 1 LFSDEDDR 8 0 H0Y322;Q5TKA1;Q5TKA1-2;B1B047 H0Y322 LIN9 Protein lin-9 homolog 1 LFS(1)DEDDR 119.22 0.0034688 1932700.0 4751.1 6039.7 3187.8 2680.8 13712.0 16218.0 22088.0 23751.0 16037.0 19443.0 True False 4683.348442754967 6025.7154457280585 2925.7113892638536 2877.9549748866416 12905.487118829233 15524.393946004522 23231.60856258595 24854.558167288375 14230.74418290334 22803.696643830997 0.20537672097220855 0.26424292253327153 0.12829987326003725 0.12620563322855835 0.5659383792197792 0.6807840934072538 1.018765024172987 1.0899354852631837 0.624054266515299 1.0 14.47698009417763 -6.64275577110498 1.725460711829633 0.9316492119010791 0.1805375743560186 0.8601246967166266 0.13434445843348808 0.12302959153426883 0.7537099720598109 0.05397659685789823 0.05388437133380807 2.276377209400519e-07 6.64275577110498 -0.7511116375450605 down LFS(ph)DEDDRQINTR ddPTM_PC-9_AZD4547_30min_R2 3 LFSDEDDRQINTR 13 1 H0Y322;Q5TKA1;Q5TKA1-2;B1B047 H0Y322 LIN9 Protein lin-9 homolog 1 LFS(0.999)DEDDRQINT(0.001)R;LFS(0.999)DEDDRQINT(0.001)R;LFS(1)DEDDRQINTR 73.758 0.0096934 14993100.0 37762.5 38683.3 44456.9 61754.0 62630.0 37864.1 41694.4 53672.0 35223.1 40549.3 True False 49770.189491205325 51186.92023183884 43867.37245837756 47517.569389789125 53934.90557249268 35496.45184133031 45405.12082724454 45378.225659863245 37084.921156616154 39129.68134924635 1.2719293327995351 1.3081353710748969 1.1210766596038857 1.214361266213182 1.3783630153055537 0.9071490136735801 1.1603754301494984 1.1596880959710971 0.9477440111413129 1.0 15.25597574131553 -6.7581590388607395 24.999815522088454 1.0528083290610029 1.2513983345921986 0.5619215541329192 0.0980581855110993 74.34799478621117 566613.9615050714 0.03344796825370718 0.03213692363539525 1.7451829490033735e-07 6.7581590388607395 0.19859000553119577 LFS(ph)DEDDRQINTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LFSDEDDRQINTR 13 1 H0Y322;Q5TKA1;Q5TKA1-2;B1B047 H0Y322 LIN9 Protein lin-9 homolog 1 LFS(1)DEDDRQINTR;LFS(0.999)DEDDRQINT(0.001)R 69.045 0.014825 4594900.0 10289.900000000001 10066.2 7275.4 11681.1 17561.6 17498.4 23246.0 25708.0 21703.0 16105.0 True False 12031.776835211054 11065.505810801795 7448.873128108151 11026.645837637161 14120.530547000424 16580.753099827325 21043.970593534326 25033.192239877553 22020.36531695788 19024.709012890155 0.6324289547377018 0.5816386365386395 0.39153677057878683 0.5795960311490745 0.7422205794282102 0.871537803211238 1.1061388943860337 1.315825236691734 1.1574613468220736 1.0 14.215586767108976 -6.886076000062935 1.414315595637577 1.1844243124424976 0.5383709642995588 0.881737407839397 0.09804854279170747 0.12720961881869208 0.5263418737234855 0.049359906608913255 0.04005966546124094 1.2999420726690498e-07 6.886076000062935 -0.6460533481429388 LFS(ph)DEDDRQINTR ddPTM_PC-9_Lapatinib_30min_R1 3 LFSDEDDRQINTR 13 1 H0Y322;Q5TKA1;Q5TKA1-2;B1B047 H0Y322 LIN9 Protein lin-9 homolog 1 LFS(1)DEDDRQINTR;LFS(1)DEDDRQINTR;LFS(0.975)DEDDRQINT(0.025)R 87.824 0.0032591 8301500.0 10757.3 12382.8 18378.9 18230.199999999997 32786.2 40716.3 44229.9 39125.4 51068.8 42814.5 True False 10603.89892935278 12354.12838739696 16867.857786605622 19570.909722164444 30857.780176149277 38974.95876333111 46519.90780343717 40943.308918294984 45316.8939656952 50214.929278264746 0.21117024521913683 0.24602500819899345 0.3359132040818542 0.3897428514478781 0.614514062245347 0.7761627731735391 0.9264158781474786 0.8153612781451645 0.9024585838719953 1.0 15.615828731646518 -6.407112539766742 0.9588713944851975 0.9193262528752505 0.2185668866889043 0.975934011956249 0.044459580036086056 0.07700320123259038 0.15250880789569135 0.022452673709609086 0.030124906276483066 3.916403772507095e-07 6.407112539766742 -0.7007593661863462 down LFS(ph)QGQDVSNK ddPTM_PC-9_AZD4547_30min_R2 4 LFSQGQDVSNK 11 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;H0Y8L4;H0Y948;H0Y8U8 A8MQ02 MLLT4 Afadin 1 LFS(1)QGQDVSNK;LFS(1)QGQDVSNK;LFS(1)QGQDVSNK;LFS(0.996)QGQDVS(0.004)NK 127.03 0.00038110000000000005 76477000.0 164555.0 151766.0 190656.0 224792.0 249149.0 229132.0 184086.0 211569.0 209279.0 242141.0 True False 216880.0670433705 200821.39155411403 188127.77686758255 172969.67740177907 214558.96197478802 214804.33981813135 200469.29737816457 178875.87242196273 220341.0606884539 233663.71729198395 0.9281717741927354 0.8594461899412887 0.8051219035966114 0.7402504736567116 0.9182382462343402 0.9192883786476524 0.8579393484854135 0.765526948278586 0.9429836315285433 1.0 17.834074207929802 LFS(ph)QGQDVSNK ddPTM_PC-9_Lapatinib_30min_R1 2 LFSQGQDVSNK 11 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;H0Y8L4;H0Y948;H0Y8U8 A8MQ02 MLLT4 Afadin 1 LFS(0.997)QGQDVS(0.003)NK;LFS(0.998)QGQDVS(0.002)NK 130.66 0.00019804 20725000.0 15216.2 11057.8 24194.0 43677.0 115403.0 177010.0 168941.0 148404.0 203597.0 187420.0 True False 14999.21419769067 11032.196343489206 22204.862711540773 46889.15228220076 108615.2224310276 169439.6949304636 177687.93834533836 155299.39161543807 180665.76188854332 219815.29727854795 0.06823553402966219 0.05018848314960222 0.10101600291904604 0.21331159779468511 0.49412039915216355 0.7708275858333515 0.8083511045192356 0.7064994726852157 0.8218980395145352 1.0 17.74593226354454 -6.406197771819914 1.4178993719848625 0.8218223942772347 0.058221445991458336 0.9608015653490966 0.0684336835405509 0.07221403881839214 0.2946635966214346 0.026779127628749205 0.032861429585271024 3.9246617092512504e-07 6.406197771819914 -0.7636009482857764 down LFSLS(ph)NPSLSTTNLSGPSR ddPTM_PC-9_AZD4547_30min_R2 1 LFSLSNPSLSTTNLSGPSR 19 0 Q6UUV7;Q6UUV7-3 Q6UUV7 CRTC3 CREB-regulated transcription coactivator 3 1 LFS(0.364)LS(0.496)NPS(0.086)LS(0.026)T(0.021)T(0.005)NLS(0.001)GPSR 108.97 0.00017341 15294000.0 4037.4 6707.2 19046.0 30247.0 29756.0 24535.0 25222.0 39670.0 22629.0 30732.0 True False 5321.209216863088 8875.171233555297 18793.437595564676 23274.021461491604 25624.893025947516 23000.822571434135 27466.709138511716 33539.913025912465 23825.1227419809 29656.082034092782 0.17943062103570523 0.2992698503919822 0.6337127599647062 0.7847975816473556 0.8640687261550265 0.7755853435053314 0.9261745738002697 1.130962376869433 0.803380659474553 1.0 14.85604039058039 -5.2737944189537975 0.8529044482760756 0.9425586087621471 2.0492417399023854e-20 0.8954061874840296 0.09133522062698911 0.38865251124978606 0.35531499743242795 0.03681842982987248 0.30015565197977073 5.323602018367733e-06 5.2737944189537975 -0.9425586087621471 down LFSLS(ph)NPSLSTTNLSGPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LFSLSNPSLSTTNLSGPSR 19 0 Q6UUV7;Q6UUV7-3 Q6UUV7 CRTC3 CREB-regulated transcription coactivator 3 1 LFS(0.001)LS(0.681)NPS(0.209)LS(0.064)T(0.044)T(0.001)NLSGPSR;LFSLS(0.922)NPS(0.07)LS(0.005)T(0.001)T(0.001)NLSGPSR 169.06 5.777e-08 24461000.0 8315.4 19864.8 32242.0 40553.0 48334.0 54080.0 51727.0 47042.0 46169.0 41568.0 True False 9723.032983363693 21836.84606211037 33010.77155846594 38280.94688459991 38863.29966852217 51243.94959760103 46827.044088950795 45807.19734511905 46844.13428183331 49103.94934789304 0.19800918485146024 0.44470651245178 0.6722630663491097 0.7795899798891119 0.7914495714628242 1.0435810210406185 0.9536309138230256 0.93286177493755 0.953978954929891 1.0 15.583551442286678 -5.148534786294008 0.7523655217689901 0.9697152976843212 1.8328148763083595e-16 0.9582606824359292 0.052662468678174854 0.3441588021346114 0.2096057880375765 0.023409405172814333 0.25802964399357176 7.103382707638324e-06 5.148534786294008 -0.969715297684321 down LFSLS(ph)NPSLSTTNLSGPSR ddPTM_PC-9_Lapatinib_30min_R1 3 LFSLSNPSLSTTNLSGPSR 19 0 Q6UUV7;Q6UUV7-3 Q6UUV7 CRTC3 CREB-regulated transcription coactivator 3 1 LFSLS(0.725)NPS(0.233)LS(0.024)T(0.003)T(0.015)NLSGPSR;LFS(0.011)LS(0.343)NPS(0.09)LS(0.136)T(0.209)T(0.209)NLS(0.001)GPS(0.002)R;LFS(0.002)LS(0.614)NPS(0.1)LS(0.204)T(0.063)T(0.016)NLSGPSR 150.61 4.018e-05 25281000.0 57665.0 79834.1 83131.0 60626.0 71178.8 73212.0 67072.5 76373.9 89691.0 43694.8 True False 56842.68652553415 79649.2490464423 76296.29007494001 65084.63828240729 66992.20292690498 70080.89342550759 70545.18586173697 79922.51021062976 79589.05509189887 51247.387960338725 1.1091821220142133 1.5542109015992052 1.4887839773216751 1.2700088896779962 1.3072315603431623 1.367501763792224 1.3765615901503734 1.5595430985181766 1.5530363255488118 1.0 15.6451908529929 -4.740735352522501 24.771339484393252 1.4000082747912377 1.1091809373615007 0.2012560652277423 0.16359980218358508 2193.725923801461 2624531.885983083 0.039581216123011964 1.6891427152084646 1.8166223267617056e-05 4.740735352522501 -0.290827337429737 LFSSSS(ph)SPPPAK ddPTM_PC-9_Lapatinib_30min_R1 1 LFSSSSSPPPAK 12 0 E9PFH7;A0A087WYG2;A0A669KB35;Q9UPT6 E9PFH7 MAPK8IP3 C-Jun-amino-terminal kinase-interacting protein 3 1 LFS(0.001)S(0.007)S(0.116)S(0.626)S(0.25)PPPAK 104.07 0.0019545 5540500.0 40611.0 39056.0 40696.0 33309.0 39246.0 38523.0 37773.0 34253.0 45089.0 28509.0 True False 40031.87969285472 38965.56823159347 37350.131971102885 35758.65497556666 36937.62744060473 36875.46109149905 39728.70111529155 35844.5194267243 40010.6020117808 33436.742664145335 1.1972422103119944 1.1653517994555362 1.1170385927321183 1.069441941003157 1.1047017292211732 1.1028425065770864 1.1881749820652587 1.0720099079854706 1.1966058540350792 1.0 15.029146689552679 -11.931286504016494 2.159869681006292 0.00011616757608758985 1.131170297298201 0.4238103465072357 0.046987573384579574 804304.8609932481 142708.7119997479 3956467.5057795993 0.012033687025089407 1.1714223234250487e-12 11.931286504016494 1.1310541297221133 LFSSSSS(ph)PPPAK ddPTM_PC-9_AZD4547_30min_R2 1 LFSSSSSPPPAK 12 0 E9PFH7;A0A087WYG2;A0A669KB35;Q9UPT6 E9PFH7 MAPK8IP3 C-Jun-amino-terminal kinase-interacting protein 3 1 LFS(0.002)S(0.018)S(0.039)S(0.276)S(0.664)PPPAK 105.2 0.0018189 9113300.0 43447.0 50914.0 66354.0 67278.0 71750.0 64189.0 54044.0 70892.0 52328.0 55570.0 True False 57262.242246260146 67370.95482246461 65474.102605066524 51768.09653473833 61788.75099515174 60175.25168281176 58853.811302899274 59937.27033609744 55093.951250270715 53624.51121419162 1.0678370944499316 1.2563462733182924 1.220973415376119 0.9653812288929173 1.1522482834081194 1.1221594438866698 1.0975169744264957 1.1177215228441124 1.0274023949646782 1.0 15.710604972099617 -7.907276713485086 0.1508625464935472 0.9320878005534772 1.2350899971726703 0.25002529288812825 0.07597774997128703 6.559228091242047 1.0244523420255192 0.8604881045525157 0.8871319514430063 1.2380075308267387e-08 7.907276713485086 0.30300219661919314 LFVGGLK ddPTM_PC-9_Lapatinib_30min_R1 2 LFVGGLK 7 0 Q13151 Q13151 HNRNPA0 Heterogeneous nuclear ribonucleoprotein A0 0 ; 126.05 0.021051 25253000.0 229780.0 250610.0 247690.0 253960.0 229610.0 229720.0 245630.0 225230.0 217646.0 247920.0 False True 226503.29506350873 250029.7279424319 227325.88431104913 272637.0655857255 216104.7912306287 219895.4111034752 258347.5195231795 235695.00804253964 193132.41556601488 290772.64166736463 0.7789704484049151 0.8598805118277206 0.7817994258589956 0.937629702788938 0.7432088176914741 0.7562451881392236 0.8884863377852498 0.8105817888884052 0.6642042196904917 1.0 18.14953200921157 -10.721977551493229 5.237781504753218 1.000012314679481 0.8070838557714912 0.38872676011601615 0.07414657899810739 1.0456240932459059e-05 1.598720138453904e-06 0.07040240142286798 0.01707400094189017 1.8968039637098058e-11 10.721977551493229 -0.19292845890798982 LFVGNLPADITEDEFKR ddPTM_PC-9_Lapatinib_30min_R1 1 LFVGNLPADITEDEFKR 17 1 P23246;P23246-2 P23246 SFPQ Splicing factor, proline- and glutamine-rich 0 86.772 0.0019038 1344200.0 24022.0 15248.0 19449.0 12356.0 15338.0 14416.0 12622.0 9533.7 13568.0 11516.0 False True 23679.441874904725 15212.69419283432 17849.978295311095 13264.701458407686 14435.848995668237 13799.461285337338 13275.505400079683 9976.670506482978 12039.82896262596 13506.525255894556 1.7531853253352838 1.1263218262739452 1.3215818248680176 0.982095780157718 1.06880553822443 1.0216884819665175 0.982895685497345 0.738655599235557 0.8914083181661769 1.0 13.721368948301429 -1.5228787452808366 0.4769920919183446 0.9061260682335092 21.653737860515506 0.7842693392901001 0.12235524605082274 43.691664284458994 0.49342063585711854 0.07027914233829388 897.2764455298545 0.02999999999996553 1.5228787452808366 20.747611792281997 LFVGNLPPDITEEEMR ddPTM_PC-9_Lapatinib_30min_R1 1 LFVGNLPPDITEEEMR 16 0 Q15233;C9JYS8;C9IZL7;C9J4X2 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 101.72 0.011692000000000001 0.0 10640.0 8572.5 11359.0 9012.9 10323.0 10068.0 8863.2 8381.9 11337.0 8934.7 False True 10488.271648862974 8552.650902942833 10425.106867008004 9675.738732153017 9715.821435798878 9637.415109654303 9322.093128029337 8771.35367363035 10060.107676097481 10479.0509902606 1.0008799135161135 0.8161665508538707 0.994852193838666 0.9233411251787785 0.9271661570144968 0.9196839597985993 0.8895932596084741 0.837037025755728 0.9600208726388971 1.0 13.355220448176821 -7.009992973813401 6.29046150327317 0.907567356756856 0.9285283146975176 0.0 0.062355009857944614 0.7894692602052651 136.37890639532884 0.022026357541400116 0.01812875587676197 9.772530312110517e-08 7.009992973813401 0.020960957940661662 LFVGS(ph)IPK ddPTM_PC-9_Lapatinib_30min_R1 2 LFVGSIPK 8 0 O43390-4;O43390;O43390-2;B4DT28;O43390-3;O60506-2;O60506;O60506-4;O60506-3;B7Z645;O60506-5 O43390-4;O60506-2 HNRNPR;SYNCRIP Heterogeneous nuclear ribonucleoprotein R;Heterogeneous nuclear ribonucleoprotein Q 1 LFVGS(1)IPK;LFVGS(1)IPK 88.177 0.011170999999999999 6530700.0 95916.0 87417.0 89090.0 82622.0 88620.0 80986.0 76793.0 72814.0 79640.0 64486.0 True False 94548.22025115983 87214.59130738449 81765.3640973449 88698.29749891214 83407.54583362353 77522.4175675867 80768.96578896527 76197.20426057577 70670.10455362118 75632.31917780603 1.2501034118613223 1.1531391904345731 1.0810902665184776 1.1727565472425745 1.1028029649274473 1.024990617904195 1.0679160267330077 1.0074688319611322 0.9343902887267141 1.0 16.20671523772424 -5.892252483501791 0.35918728366548736 0.963081649358897 1.2819728920771967 0.7724212587700137 0.04251966842191911 1.452903161308055 0.26756296196447876 0.04594834205995932 0.1879700154665745 1.281585297522931e-06 5.892252483501791 0.3188912427182997 LFVGSIPK ddPTM_PC-9_Lapatinib_30min_R1 2 LFVGSIPK 8 0 O43390-4;O43390;O43390-2;B4DT28;O43390-3;O60506-2;O60506;O60506-4;O60506-3;B7Z645;O60506-5 O43390-4;O60506-2 HNRNPR;SYNCRIP Heterogeneous nuclear ribonucleoprotein R;Heterogeneous nuclear ribonucleoprotein Q 0 ; 116.88 0.016452 8013100.0 81026.0 86669.0 80334.0 89675.0 79867.0 85730.0 83309.0 73664.0 77884.0 74807.0 False True 79870.55438165157 86468.32325542765 73729.24861820764 96269.99864703038 75169.38008456341 82063.52774639081 87622.33238593233 77086.69836365331 69111.88376512086 87737.29027593795 0.9103376013831164 0.9855367425125697 0.840341072608074 1.0972529279654826 0.8567552046359322 0.9353323710852833 0.9986897487984405 0.878608150778443 0.7877139075957407 1.0 16.420902529651357 -7.869265319126352 9.509524135751972 0.8738779282608535 0.9456377957225092 0.08146657676591906 0.08430244570377896 0.5968673301445874 48.60096739391823 0.04326471151835388 0.020752739601385333 1.3512468074671671e-08 7.869265319126352 0.07175986746165564 LFVLLPEQS(ph)PVSYSK ddPTM_PC-9_AZD4547_30min_R2 1 LFVLLPEQSPVSYSK 15 0 Q96K76-2;Q96K76-4;Q96K76 Q96K76-2 USP47 Ubiquitin carboxyl-terminal hydrolase 47 1 LFVLLPEQS(0.995)PVS(0.005)YSK 152.34 4.7608e-10 0.0 4017.9 4060.2 4457.2 6030.9 6945.9 6845.0 4359.5 5839.9 4910.8 4656.6 True False 5295.508622488289 5372.580248461531 4398.094615717258 4640.5691814761685 5981.581679961311 6416.981067922019 4747.487054529448 4937.477642551709 5170.374862403098 4493.573851358729 1.1784625773730362 1.1956140983055201 0.9787520493042301 1.0327123432216412 1.3311412870520978 1.4280350741274022 1.0565058484782535 1.0987863571127814 1.1506153083118291 1.0 12.133647597501456 -8.763188614726577 1.0013749824035902 1.0031373623209878 1.1702710606100006 0.12932389434741598 0.12852055422481323 2.155874433829147 4.178489952855302 0.1365343009162711 0.04437632086560559 1.7250885208161738e-09 8.763188614726577 0.1671336982890128 LFVLLPEQS(ph)PVSYSK ddPTM_PC-9_Lapatinib_30min_R1 2 LFVLLPEQSPVSYSK 15 0 Q96K76-2;Q96K76-4;Q96K76 Q96K76-2 USP47 Ubiquitin carboxyl-terminal hydrolase 47 1 LFVLLPEQS(0.791)PVS(0.209)YSK;LFVLLPEQS(0.955)PVS(0.041)YS(0.004)K 187.75 3.5679e-38 1774100.0 17064.3 23925.4 24387.9 20352.3 24815.1 25988.9 22587.6 21937.5 24635.0 21067.6 True False 16820.959952790636 23870.0022062722 22382.821002016415 21849.076035282513 23355.524606363706 24877.415330084885 23757.075406024385 22956.796336781128 21860.346881949492 24709.10658918756 0.6807595366540411 0.9660406830215973 0.9058531080929854 0.8842519642067284 0.9452193069814929 1.0068116077078633 0.9614704327844953 0.9290824115359467 0.8847081056146056 1.0 14.592755227421726 -4.757951105768937 24.997296597476048 0.9400938125286296 0.6807591724161913 0.7870933065507937 0.040836336137547814 46.86763894062944 335806.0306821626 0.010628922482656863 0.07574836143259092 1.7460187141032053e-05 4.757951105768937 -0.25933464011243823 LFVT(ph)PPEGSSR ddPTM_PC-9_AZD4547_30min_R2 1 LFVTPPEGSSR 11 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 LFVT(0.821)PPEGS(0.048)S(0.131)R 78.705 0.044242000000000004 10836000.0 96609.0 95751.0 77474.0 142590.0 115000.0 94523.0 82072.0 107340.0 98441.0 86435.0 True False 127328.65240796718 126700.63823714109 76446.64413938769 109718.07849353936 99034.23504449413 88612.46186752275 89376.24900546894 90753.06942781544 103644.39028871541 83408.9369587664 1.5265588682770612 1.5190295291711504 0.9165282154018993 1.3154235324660595 1.187333619818847 1.0623856998840393 1.0715428377855063 1.0880497071036843 1.2426053378423048 1.0 16.347914350933216 -5.2412774270330775 24.634371769334567 1.1205836582518012 1.522794357312265 0.6925921781656912 0.10971111613921392 365.88648353924754 447047.1114330097 0.0271250378289903 0.07155656211475256 5.737498340973767e-06 5.2412774270330775 0.4022106990604639 LFVT(ph)PPEGSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LFVTPPEGSSR 11 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 LFVT(0.978)PPEGS(0.018)S(0.003)R 78.705 0.044242000000000004 5044200.0 56664.0 63652.0 57467.0 45801.0 62842.0 46129.0 49817.0 50280.0 41689.0 32691.0 True False 66256.09603498579 69970.94989858699 58837.23122481111 43234.918458845445 50528.56121507157 43709.91403453655 45097.97311615328 48960.2032760636 42298.6227571606 38617.61951818639 1.7156960180775378 1.811891845524948 1.5235851396045426 1.1195645665959448 1.308432830544511 1.1318645369622544 1.1678082097969573 1.2678203340059977 1.0953192683780184 1.0 15.236971615429034 -5.576524244417347 3.1041357847794977 1.17205663239646 1.758155694225602 0.8893361494050254 0.08764313978864198 0.07033913167190918 1.3717150139131788 0.023411055667996533 0.04708322477391773 2.6514030747412623e-06 5.576524244417347 0.586099061829142 LFVTNDAATILR ddPTM_PC-9_Lapatinib_30min_R1 1 LFVTNDAATILR 12 0 P50990-2;P50990;H7C4C8 P50990-2 CCT8 T-complex protein 1 subunit theta 0 133.91 0.00025712 5253200.0 14398.0 17795.0 19781.0 13599.0 14702.0 14983.0 13601.0 11953.0 16421.0 13036.0 False True 14192.681879730164 17753.796770821533 18154.682536868142 14599.115824934144 13837.257265244123 14342.212017078893 14305.19322979589 12508.380016571844 14571.494059204073 15289.255230621862 0.92827817088857 1.1611943487779313 1.1874144464870533 0.95486114952771 0.9050314784156637 0.9380582507612145 0.9356370218181028 0.8181157177309473 0.953054536627773 1.0 13.900230511476558 -5.90259970583832 6.333222068746277 0.9182337922430276 1.0981526184847712 0.4843001757130171 0.07727931850226803 0.16390712344047464 9.01634251443914 0.021691685118281828 0.03245646945646067 1.251411939423829e-06 5.90259970583832 0.1799188262417436 LGADES(ph)EEEGRR ddPTM_PC-9_Lapatinib_30min_R1 1 LGADESEEEGRR 12 1 F5H7V1;O43847;O43847-2 F5H7V1 NRD1 Nardilysin 1 LGADES(1)EEEGRR 71.806 0.03897 3515000.0 19204.0 17623.0 22355.0 18153.0 25043.0 21243.0 19312.0 21191.0 23107.0 17142.0 True False 18930.147438417713 17582.19502625389 20517.058192795488 19488.032176632805 23570.019976432348 20334.48640985163 20311.88086565829 22175.611221548905 20504.446332502805 20104.971859720776 0.9415654779573822 0.8745197530705758 1.0204967376204244 0.9693140737827156 1.172347822264482 1.0114158105632902 1.0102914347446588 1.1029914081091823 1.0198694370511583 1.0 14.295264696395522 -5.521764350253194 1.8737172415327532 1.0509467308298608 0.9074154333977186 0.4354199410759604 0.0581804199549054 0.3094907991642189 2.112058286322616 0.016674154719624898 0.04541114258400321 3.0077078530368964e-06 5.521764350253194 -0.1435312974321422 LGADESEEEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGADESEEEGR 11 0 F5H7V1;O43847;O43847-2 F5H7V1 NRD1 Nardilysin 0 ; 166.34 1.0806e-17 0.0 17785.7 21990.0 49931.0 31827.0 44584.0 34809.0 27713.0 35252.0 31266.0 21082.8 False True 20796.467726412633 24173.021873152884 51121.54440437197 30043.836374526207 35848.085248921925 32983.55476225765 25087.824015254955 34326.67235258142 31723.206100539326 24904.944748647013 0.8350336825197102 0.9706113431336204 2.0526664451704595 1.206340213870917 1.4393962970293042 1.3243777528978262 1.0073430906373675 1.3783075087707735 1.2737713904088352 1.0 14.604144589960015 -7.084159610815362 24.99999761507676 1.1920206035328884 1.3252894871092715 0.038537735182572086 0.3216764814757824 382.3575541457189 113574.72808208612 0.12735232097535804 0.09864670059008522 8.238352854973731e-08 7.084159610815362 0.1332688835763831 LGADESEEEGR ddPTM_PC-9_Lapatinib_30min_R1 1 LGADESEEEGR 11 0 F5H7V1;O43847;O43847-2 F5H7V1 NRD1 Nardilysin 0 128.35 0.0014487999999999999 5148700.0 13393.0 13651.0 14632.0 11905.0 18119.0 16783.0 12704.0 10780.0 18152.0 11900.0 False True 13202.013364024604 13619.391948214932 13429.013441153358 12780.533413915791 17053.276043324604 16065.230213083849 13361.750958850595 11280.878154324808 16107.530610965976 13956.899144246709 0.9459130733538844 0.9758178953259182 0.9621774365754477 0.9157143919882923 1.2218527817014626 1.1510601349946872 0.9573581367003396 0.8082653630820994 1.154090922667862 1.0 13.768690827820661 LGADESEEEGRRGS(ph)LSNAGDPEIVK ddPTM_PC-9_AZD4547_30min_R2 1 LGADESEEEGRRGSLSNAGDPEIVK 25 2 F5H7V1;O43847;O43847-2 F5H7V1 NRD1 Nardilysin 1 LGADES(0.068)EEEGRRGS(0.466)LS(0.466)NAGDPEIVK 53.342 0.030202999999999997 38266000.0 54256.0 28418.0 49920.0 85256.0 72582.0 47508.0 35964.0 50990.0 42509.0 52436.0 True False 71508.27940509318 37603.562755721345 49258.02818285143 65601.54639206955 62505.24215651699 44537.31724979392 39164.72632850033 43110.66713363443 44755.93895615652 50600.23160027622 1.4132006345343058 0.743150012687216 0.973474362172337 1.296467314819789 1.2352758115869134 0.8801801067161676 0.7740029065061933 0.8519855694375733 0.8845006740228477 1.0 15.626856367785345 -6.836013336757809 8.255306610965995 0.8609341867367892 1.1106847868840988 0.32809256623530625 0.1797862756801297 0.3436660390041273 33.751971951733964 0.06529499757813445 0.05765801872585742 1.458769462207319e-07 6.836013336757809 0.24975060014730954 LGADESEEEGRRGSLS(ph)NAGDPEIVK ddPTM_PC-9_AZD4547_30min_R2 1 LGADESEEEGRRGSLSNAGDPEIVK 25 2 F5H7V1;O43847;O43847-2 F5H7V1 NRD1 Nardilysin 1 LGADESEEEGRRGS(0.233)LS(0.766)NAGDPEIVK 62.303000000000004 0.0057473 25312000.0 48561.0 27231.0 51107.0 68327.0 50287.0 38338.0 37312.0 37708.0 34866.0 44524.0 True False 64002.387868452104 36032.888218771506 50429.28778727939 52575.265791626756 43305.51806680407 35940.718799414804 40632.695717078306 31881.095043637684 36708.94557965027 42965.22831205086 1.48963220685367 0.8386523157067695 1.173723258748168 1.2236701131850027 1.007920119783415 0.8365071061273559 0.9457111555876843 0.7420208456030872 0.8543873039155753 1.0 15.390881940864283 -6.530042333523009 3.579173757281839 0.8649569137946883 1.1552530829647107 0.44014969321073616 0.16086413583611966 0.2268193874561969 6.264216796121935 0.05222777230100401 0.055143376357480435 2.9509215670253227e-07 6.530042333523009 0.29029616917002243 LGADESEEEGRRGSLS(ph)NAGDPEIVK ddPTM_PC-9_Lapatinib_30min_R1 1 LGADESEEEGRRGSLSNAGDPEIVK 25 2 F5H7V1;O43847;O43847-2 F5H7V1 NRD1 Nardilysin 1 LGADES(0.139)EEEGRRGS(0.146)LS(0.716)NAGDPEIVK 52.909 0.035729000000000004 29640000.0 127490.0 66246.0 94325.0 84363.0 80381.0 57863.0 44180.0 36315.0 80383.0 45926.0 True False 125671.96922119726 66092.61145714197 86569.96260502927 90567.3364467181 75653.14761512638 55388.334375241044 46467.42422559977 38002.32747442537 71329.42006948432 53864.2479074516 2.333123994177439 1.2270218934589208 1.6071878095053314 1.6813998146289717 1.404515064335661 1.0282949549468898 0.8626765624842493 0.7055204323973883 1.3242442406703794 1.0 15.717040389436457 -6.627634742478223 2.258399336433784 0.9446411307978647 1.6719311370450187 0.5798134366515326 0.2920196254783181 0.22234382398923935 2.3118953958174737 0.10550605467797385 0.10603239615559316 2.3570307995080462e-07 6.627634742478223 0.727290006247154 LGAES(ph)PSIASTSSTEK ddPTM_PC-9_AZD4547_30min_R2 1 LGAESPSIASTSSTEK 16 0 A0A0D9SF60;Q99569-2;Q99569;H0YFB1;E7EST6 A0A0D9SF60 PKP4 Plakophilin-4 1 LGAES(0.911)PS(0.089)IAS(0.001)TSSTEK 162.46 2.8855e-15 0.0 10627.0 13687.0 19219.0 15327.0 22471.0 15355.0 19343.0 19814.0 16003.0 17205.0 True False 14006.164944668355 18111.05508612703 18964.14350252847 11793.596949789455 19351.289527694127 14394.849422635876 21064.489527643804 16752.20158042424 16848.885909227996 16602.658186794433 0.8436097874862413 1.0908527346863264 1.1422353751528977 0.7103438989769691 1.1655536908593302 0.8670207662340105 1.2687419864126492 1.0090071958325777 1.0148306204743414 1.0 14.019126623886109 -7.214948674969593 24.99989869172104 1.0738967054483992 0.9803561665142083 0.09838543545591272 0.15109220707864593 1118.377865912814 601397.0081341951 0.055750808268979456 0.04318428688309069 6.096089367197543e-08 7.214948674969593 -0.0935405389341909 LGAESPS(ph)IASTSSTEK ddPTM_PC-9_Lapatinib_30min_R1 1 LGAESPSIASTSSTEK 16 0 A0A0D9SF60;Q99569-2;Q99569;H0YFB1;E7EST6 A0A0D9SF60 PKP4 Plakophilin-4 1 LGAES(0.405)PS(0.53)IAS(0.049)T(0.007)S(0.007)S(0.002)TEK 100.23 0.010581 0.0 18566.0 21330.0 22859.0 19138.0 17884.0 17983.0 22055.0 14796.0 18254.0 18194.0 True False 18301.24543541259 21280.611695511296 20979.62125829174 20545.47236249648 16832.09828129681 17213.909010420466 23196.899984056196 15483.47617545361 16198.042296858377 21338.80865801888 0.8576507587050879 0.9972727173554877 0.9831674108201837 0.9628219031232433 0.7888021562521252 0.8066949418917854 1.0870756824251793 0.7256017158031499 0.7590884081886802 1.0 14.381192012546565 -6.2358518424899945 23.76529215872384 0.8560580503204169 0.9559413506845202 0.1353612920223004 0.1093747675779414 801.4088507068666 744334.0349326669 0.032631997478704974 0.042106768267028555 5.809625763561832e-07 6.2358518424899945 0.09988330036410331 LGAGEGGEAS(ph)VSPEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGAGEGGEASVSPEK 15 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 LGAGEGGEAS(0.714)VS(0.286)PEK 98.421 0.0022593000000000005 84379000.0 47880.0 65228.0 56560.0 55754.0 69160.0 51072.0 65472.0 47039.0 39340.0 40481.0 True False 55985.1383268939 71703.40476316569 57908.60490499448 52630.28413690681 55608.59446921403 48393.69441288235 59270.01818376836 45804.276091940264 39915.27307603198 47819.884852580326 1.1707501701328957 1.499447457563182 1.2109733238278546 1.100594121026348 1.162875959250944 1.0119993923463215 1.2394429297871927 0.9578499871579824 0.8347003176415676 1.0 15.54532303567989 -6.303972846041816 0.45829970345199783 0.9373408053187912 1.3844648795840138 0.5079391265744551 0.12251728044028677 1.2124751678512145 0.480861221006752 0.11102694193760211 0.252029943120493 4.96623371507969e-07 6.303972846041816 0.4471240742652226 LGAGEGGEAS(ph)VSPEK ddPTM_PC-9_Lapatinib_30min_R1 1 LGAGEGGEASVSPEK 15 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 LGAGEGGEAS(0.5)VS(0.5)PEK 82.48299999999999 0.00775 6102800.0 12824.0 20657.0 15267.0 16678.0 22085.0 18268.0 20954.0 18371.0 14978.0 16048.0 True False 12641.127408366416 20609.169985662287 14011.806192324244 17904.555756177047 20786.00372078059 17486.720224787918 22038.895591290573 19224.58372663275 13291.019914667726 18821.875417384148 0.6716189076828599 1.0949583677845072 0.7444426169871863 0.9512631105633687 1.1043534854971118 0.9290636473258631 1.1709192151455396 1.021395758941038 0.7061474810523904 1.0 14.200122765350175 -4.746225547736408 24.975510274370862 0.9715333954044388 0.6716180920927948 0.2846350406072955 0.14147109642630137 1129.3975029507303 1853951.4824108519 0.03495788782772476 0.8176678590472143 1.7938017867388965e-05 4.746225547736408 -0.29991530331164407 LGAGEGGEAS(ph)VSPEKTSTTSK ddPTM_PC-9_AZD4547_30min_R2 1 LGAGEGGEASVSPEKTSTTSK 21 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 LGAGEGGEAS(0.744)VS(0.255)PEKT(0.001)STTSK 80.596 0.0004026 351370000.0 139810.0 99358.0 133140.0 194060.0 179470.0 167530.0 139050.0 140140.0 110830.0 157070.0 True False 184266.67177134508 131473.5304484118 131374.47660786932 149322.46519711244 154553.6883776989 157054.3226163588 151425.18062445658 118484.58309683338 116688.24753607059 151571.0271083874 1.2157117048469774 0.8674054201295078 0.8667519057842389 0.9851649622347216 1.0196783074325848 1.0361764092556445 0.9990377680569088 0.7817099702841352 0.7698585261458155 1.0 17.209634482287825 -7.752134980573796 24.911069253338596 0.8318381842820918 0.9901906539340557 0.272278589180976 0.10903831950053647 224.21658714454819 600309.1947127914 0.05184912561839043 0.029408638475491636 1.7695588864044776e-08 7.752134980573796 0.15835246965196392 LGAGEGGEAS(ph)VSPEKTSTTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGAGEGGEASVSPEKTSTTSK 21 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 LGAGEGGEAS(0.498)VS(0.498)PEKT(0.001)S(0.001)T(0.001)TSK 72.935 0.00091889 5898300.0 18046.0 38433.0 11385.0 35988.0 21118.0 24660.0 19925.0 24673.0 22500.0 22467.0 True False 21100.83137525329 42248.37424515167 11656.461577852935 33971.70903467022 16980.079496831448 23366.78618855105 18037.559755492195 24025.35989320441 22829.01993418199 26540.08925132586 0.7950550269607386 1.5918700892477622 0.4392020489256876 1.2800148753445921 0.6397898415501062 0.8804335949014837 0.6796344799251606 0.9052478936936574 0.8601711817167881 1.0 14.695885601886369 -5.261489743923918 24.999999999998938 0.8370929530175478 1.19346251588773 0.2103569404497626 0.2773573136051878 6.08826491769226 3024033.414951207 0.06524252755400878 0.1513462888283614 5.476590340444741e-06 5.261489743923918 0.35636956287018207 LGAGEGGEAS(ph)VSPEKTSTTSK ddPTM_PC-9_Lapatinib_30min_R1 1 LGAGEGGEASVSPEKTSTTSK 21 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 LGAGEGGEAS(0.545)VS(0.448)PEKT(0.005)S(0.001)TTSK 72.271 0.0010176 4861700.0 8059.9 48294.0 6753.5 17695.0 5649.9 5472.7 4581.0 4768.2 6694.5 9235.9 True False 7944.964347995365 48182.17821017452 6198.2532992638935 18996.349328789587 5317.583990130781 5238.645378486798 4818.181764994852 4989.747979169903 5940.494913789762 10832.313008936822 0.7334504035694546 4.448004610873365 0.5722003503914852 1.7536743365075687 0.49090014161737144 0.4836128141944233 0.4447971325255999 0.4606355055520724 0.5484050275217087 1.0 13.403053712082798 -5.315381305284071 24.999676615203093 0.7105812528972902 2.5907340506516765 0.4015927573536363 0.9137343861064869 243.4077631259372 112808.15896578867 0.22166653935232242 0.4614361769930101 4.83747456682372e-06 5.315381305284071 1.8801527977543864 LGAGEGGEASVS(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 9 LGAGEGGEASVSPEK 15 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 LGAGEGGEAS(0.003)VS(0.997)PEK;LGAGEGGEAS(0.286)VS(0.714)PEK;LGAGEGGEAS(0.002)VS(0.998)PEK;LGAGEGGEASVS(1)PEK;LGAGEGGEAS(0.005)VS(0.995)PEK;LGAGEGGEAS(0.033)VS(0.967)PEK;LGAGEGGEAS(0.074)VS(0.926)PEK;LGAGEGGEAS(0.052)VS(0.948)PEK;LGAGEGGEAS(0.001)VS(0.999)PEK 184.01 5.078e-07 604863900.0 286237.0 299888.0 278158.0 271397.0 284734.0 299841.0 327524.0 351588.0 317271.0 273889.0 True False 377254.4119005393 396820.93137053156 274469.44317479123 208830.6146918513 245203.59896659965 281091.8948702421 356673.0015019396 297258.15328849276 334041.2973384161 264300.22947532404 1.4273707315708595 1.5014021446681343 1.038475992698359 0.7901264978332092 0.9277464474902875 1.0635325418682082 1.3494994015328308 1.1246988089211847 1.2638706292519633 1.0 18.01181815201852 -5.262017895789753 24.991786206700894 1.0689090877036167 1.4643864672590963 0.5244555694484411 0.1503143129610018 41.97753042284779 1813515.8227678833 0.04399912845244962 0.1013727537093354 5.469934227020451e-06 5.262017895789753 0.39547737955547957 LGAGEGGEASVS(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 LGAGEGGEASVSPEK 15 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 LGAGEGGEAS(0.042)VS(0.958)PEK;LGAGEGGEASVS(1)PEK;LGAGEGGEAS(0.015)VS(0.985)PEK;LGAGEGGEAS(0.016)VS(0.984)PEK;LGAGEGGEAS(0.002)VS(0.998)PEK;LGAGEGGEAS(0.047)VS(0.953)PEK;LGAGEGGEAS(0.001)VS(0.999)PEK 166.79 1.2242e-05 527594400.0 205227.7 273569.0 201166.2 220399.3 221952.1 137550.0 225163.1 168099.5 153703.6 136197.9 True False 239968.69617815985 300727.122365465 205962.76513506213 208051.04176517183 178462.1793014814 130336.63585706413 203834.0211283243 163687.06624114237 155951.22437135704 160889.50112801697 1.4915124634964276 1.8691531781566135 1.2801504367347198 1.2931300072813903 1.109222031582298 0.810100316945837 1.2669193433954222 1.0173881147838193 0.9693064076770886 1.0 17.29571066025744 -5.684133630245368 1.4099630028510692 1.0317026959432671 1.687036671893599 0.7112618196316263 0.15555217765192306 0.22923283816436396 0.8978007488125601 0.04955817091724535 0.13109336867986143 2.0695044746125706e-06 5.684133630245368 0.6553339759503318 LGAGEGGEASVS(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 6 LGAGEGGEASVSPEK 15 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 LGAGEGGEAS(0.054)VS(0.946)PEK;LGAGEGGEAS(0.312)VS(0.688)PEK;LGAGEGGEAS(0.029)VS(0.971)PEK;LGAGEGGEAS(0.003)VS(0.997)PEK;LGAGEGGEAS(0.008)VS(0.992)PEK;LGAGEGGEASVS(1)PEK 194.77 1.3094e-09 1289438100.0 223016.0 348431.0 278761.0 297203.0 342830.0 290505.0 333593.0 338585.0 276742.0 297817.0 True False 219835.7509438746 347624.22942703596 255842.34662857745 319060.30006014486 322665.41342971276 278080.7783502305 350864.813256915 354316.89516531175 245572.40173754693 349294.2716337918 0.629371188698896 0.995218810205663 0.7324550312030553 0.913442692798166 0.9237638279049782 0.7961217830728607 1.0044963280267298 1.0143793469844984 0.7030530463294019 1.0 18.41408345741211 -4.74755044811868 24.89876776982566 0.8947953573600149 0.6293704888001574 0.3481079697894718 0.11024083312058723 770.6334971539408 1381435.6673794452 0.026177714774207658 0.5226130778318094 1.7883377817829842e-05 4.74755044811868 -0.2654248685598575 LGAGEGGEASVS(ph)PEKTSTTSK ddPTM_PC-9_AZD4547_30min_R2 3 LGAGEGGEASVSPEKTSTTSK 21 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 LGAGEGGEAS(0.033)VS(0.931)PEKT(0.018)S(0.006)T(0.007)T(0.003)S(0.002)K;LGAGEGGEAS(0.05)VS(0.922)PEKT(0.007)S(0.007)T(0.007)T(0.007)S(0.001)K;LGAGEGGEAS(0.183)VS(0.728)PEKT(0.065)S(0.009)T(0.009)T(0.004)S(0.002)K 67.413 0.0017396 870626100.0 80115.0 61202.0 74370.0 103996.0 95279.0 80791.3 76611.7 83843.1 68741.9 85294.2 True False 105589.90350447952 80984.34962965934 73383.80520750515 80021.32892218331 82051.15548525495 75739.40723927086 83429.99288347144 70887.0754177685 72375.45649462973 82308.0760195339 1.2828620059035303 0.9839174179024619 0.8915747853234867 0.9722172208616822 0.9968785501167835 0.92019411583981 1.0136307020913875 0.8612408264888262 0.8793238767657879 1.0 16.328746373522073 -4.766431852997373 4.016846810183174 0.9414044313821502 1.318485349114099 0.7993323458969045 0.050928095793909986 0.10268059990107296 3.1290532811261595 0.012924526214098443 0.11552324514142678 1.712253832688617e-05 4.766431852997373 0.37708091773194885 LGAGEGGEASVS(ph)PEKTSTTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LGAGEGGEASVSPEKTSTTSK 21 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 LGAGEGGEAS(0.006)VS(0.991)PEKT(0.001)S(0.001)T(0.001)T(0.001)SK;LGAGEGGEAS(0.011)VS(0.989)PEKTSTTSK;LGAGEGGEAS(0.004)VS(0.986)PEKT(0.004)S(0.002)T(0.003)T(0.001)SK;LGAGEGGEAS(0.257)VS(0.74)PEKT(0.001)S(0.001)TTSK 100.08 9.9117e-05 1018518000.0 111407.0 77886.0 77033.0 138833.0 115970.0 119536.0 124180.0 147688.0 112716.0 98370.0 True False 130266.00471145108 85618.00734935811 78869.75886927954 131054.63711265902 93246.51099761065 113267.3217288985 112416.7714146561 143811.34648837065 114364.25826227818 116203.7023035086 1.121014237319338 0.736792422721053 0.6787198454596759 1.1278008747979626 0.802440104309785 0.9747307485355272 0.9674112716395082 1.2375797297125228 0.9841705212074393 1.0 16.82629650884038 -7.300750271390413 2.2506939718029977 1.081118700387255 0.8879418963700919 0.17976789611032962 0.15349931221921215 0.47550140225023735 4.713771937051194 0.07540230665388906 0.04768239065275662 5.00322148206145e-08 7.300750271390413 -0.1931768040171632 LGAGEGGEASVS(ph)PEKTSTTSK ddPTM_PC-9_Lapatinib_30min_R1 6 LGAGEGGEASVSPEKTSTTSK 21 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 LGAGEGGEAS(0.027)VS(0.942)PEKT(0.015)S(0.006)T(0.004)T(0.004)S(0.002)K;LGAGEGGEAS(0.008)VS(0.955)PEKT(0.023)S(0.008)T(0.003)T(0.003)S(0.001)K;LGAGEGGEAS(0.065)VS(0.886)PEKT(0.032)S(0.005)T(0.005)T(0.005)S(0.002)K;LGAGEGGEAS(0.074)VS(0.894)PEKT(0.019)S(0.008)T(0.004)T(0.001)S(0.001)K;LGAGEGGEASVS(0.999)PEKT(0.001)STTSK;LGAGEGGEAS(0.067)VS(0.879)PEKT(0.045)S(0.005)T(0.002)T(0.001)SK 131.43 1.3432000000000001e-05 1972005800.0 353652.0 250328.0 252665.0 256528.0 232751.0 222321.0 202607.0 181222.0 230613.0 188085.0 True False 348608.8576281654 249748.3808961071 231891.85901510448 275393.9248723218 219061.04378607197 212812.84908556365 213096.9990963351 189642.23570343739 204638.9354774514 220595.24164249134 1.5803099605980617 1.132156700373723 1.051209705560744 1.2484128071930045 0.9930451906170045 0.9647209409460415 0.9660090467485771 0.8596841631370359 0.9276670428326844 1.0 17.751042145997026 -1.5228787452803376 0.5238829626756795 0.9448411327960236 22.372188822641952 0.7905256531058187 0.09080394328206595 56.24783592866152 0.5582001267125413 0.04993639983171759 1341.4843235132698 0.029999999999999995 1.5228787452803376 21.427347689845927 LGAGEGGEASVSPEKT(ph)STTSK ddPTM_PC-9_AZD4547_30min_R2 1 LGAGEGGEASVSPEKTSTTSK 21 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 LGAGEGGEAS(0.001)VS(0.022)PEKT(0.548)S(0.195)T(0.162)T(0.054)S(0.018)K 78.225 0.00081112 620950000.0 56209.0 39273.0 62431.0 76270.0 84509.0 55816.0 62280.0 70826.0 48792.0 69776.0 True False 74082.29278016965 51967.22922462681 61603.12414830929 58687.12985975348 72776.38408152285 52325.81669644052 67822.79934765327 59881.469119568304 51371.04550915775 67333.16347816131 1.1002348464467637 0.7717924799639296 0.9149001913193862 0.8715932362035527 1.0808401138783117 0.7771180499103054 1.0072718381878905 0.8893309927282732 0.762938244032145 1.0 16.039029627343368 -7.994957314098757 24.832964769910973 0.8630242744592421 0.9244321115385444 0.026471893332333463 0.11785378318661177 405.7750357604069 1998260.943815222 0.060494287240954125 0.028903149710728222 1.0116788851866035e-08 7.994957314098757 0.06140783707930231 LGAGEGGEASVSPEKT(ph)STTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGAGEGGEASVSPEKTSTTSK 21 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 LGAGEGGEAS(0.009)VS(0.335)PEKT(0.386)S(0.15)T(0.059)T(0.046)S(0.014)K 56.335 0.011491 63746000.0 18931.0 11231.0 15316.0 26649.0 26061.0 20966.0 21483.0 20885.0 22012.0 13802.0 True False 22135.644395706524 12345.93945690677 15681.191526253462 25155.942927223692 20954.534130453834 19866.506051466404 19447.97471654899 20336.790879486645 22333.8838573873 16304.193343428113 1.3576657200663627 0.7572247946803922 0.9617888598318316 1.542912451867086 1.2852236040797553 1.2184905829440613 1.1928204178459445 1.247334992361581 1.3698245222533276 1.0 13.992955444479788 -5.716478495959249 24.999978619787314 1.2714042881381293 0.9987257256048837 0.24961215064196607 0.188503145072834 158.38406387587918 88066.40199196138 0.049234630875870995 0.08527638411317022 1.9209740762051263e-06 5.716478495959249 -0.2726785625332456 LGAGEGGEASVSPEKT(ph)STTSK ddPTM_PC-9_Lapatinib_30min_R1 1 LGAGEGGEASVSPEKTSTTSK 21 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 LGAGEGGEAS(0.18)VS(0.148)PEKT(0.279)S(0.279)T(0.101)T(0.009)S(0.003)K 72.676 0.0014625 10001000.0 28468.0 14834.0 16461.0 22088.0 17287.0 18000.0 12893.0 14127.0 21106.0 12734.0 True False 28062.041099608166 14799.652784398246 15107.640121297543 23712.425203407973 16270.212647549659 17230.181960049402 13560.536454066494 14783.391993149036 18728.820023966942 14935.05493301157 1.878937923260093 0.9909339370212801 1.011555711650213 1.5877025769081985 1.0893975764084358 1.1536738255957009 0.9079669619489031 0.9898451702693569 1.254017484901904 1.0 13.86641492362183 -6.486584702766865 24.03857106865591 1.0587440104298333 1.3179363682351686 0.23876894810940807 0.2581416812060463 638.5058007624694 422900.24451873254 0.07979367631798288 0.09043779790437323 3.2614843372386745e-07 6.486584702766865 0.2591923578053352 LGAGGGS(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 2 LGAGGGSPEK 10 0 Q9UNE7;H3BS86 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 LGAGGGS(1)PEK;LGAGGGS(1)PEK 97.734 0.005031 193019000.0 454870.0 504250.0 412510.0 420700.0 462600.0 476680.0 463820.0 458860.0 493140.0 417160.0 True False 599509.1981162416 667238.9513538069 407039.84787075385 323714.1147502068 398375.9750572431 446873.1242450072 505099.0814616017 387953.73055382393 519206.37363473664 402555.3553736209 1.4892590301272313 1.6575085698078145 1.0111400641856343 0.8041480766036767 0.989617874261047 1.1100911173576462 1.2547319883319092 0.9637276597494402 1.28977634182223 1.0 18.61882765625269 -5.264473607930905 24.962936694162902 1.0497148483943282 1.5733838266171625 0.6921686597622374 0.1388268326877564 133.31688808745562 1096823.279720314 0.037675671444273265 0.08429810811558237 5.439091840689893e-06 5.264473607930905 0.5236689782228343 LGAGGGS(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LGAGGGSPEK 10 0 Q9UNE7;H3BS86 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 LGAGGGS(1)PEK;LGAGGGS(1)PEK;LGAGGGS(1)PEK 89.266 0.009459 127539000.0 849937.0 1446830.0 994329.0 933685.0 856346.0 797594.0 1044772.0 657496.0 617445.0 564354.0 True False 993814.5470790572 1590461.7206336388 1018037.5743737328 881373.6564976121 688551.1486311958 755766.76655601 945803.632665752 640237.4266745959 626473.9650338212 666666.912776193 1.4907212702975272 2.3856917002382767 1.5270557978261305 1.322059996689079 1.032826341664191 1.1336497313310174 1.4187049252634323 0.9603557854828326 0.9397106006431355 1.0 19.34660660119441 -5.661845158573927 2.4612171476218605 1.108826587683045 1.9422602253708081 0.6389587301328113 0.2485448871595099 0.1647081912821463 2.015041983683891 0.06931422490424842 0.13916260248818912 2.1784863417542497e-06 5.661845158573927 0.8334336376877631 LGAGGGS(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 4 LGAGGGSPEK 10 0 Q9UNE7;H3BS86 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 LGAGGGS(1)PEK;LGAGGGS(1)PEK;LGAGGGS(1)PEK;LGAGGGS(1)PEK 104.43 0.0026051 430275000.0 2047480.0 3103380.0 2657500.0 2788570.0 3400670.0 2640670.0 3395020.0 3357280.0 2791860.0 2572150.0 True False 2018282.5597381513 3096194.314281101 2439010.608246659 2993650.740196823 3200649.27657446 2527734.6998024243 3570797.5236395616 3513271.485153213 2477411.3272108575 3016742.7003255575 0.6690270799429943 1.0263368877786525 0.8084914261940366 0.9923453995177506 1.0609619694212091 0.8379019859829739 1.1836599532516354 1.1645910288517718 0.821220625459209 1.0 21.524560222787898 -3.8590776894909196 0.6524498837352051 1.0218861817982436 2.5333590080946698e-17 0.30998317923230356 0.13154646742295564 12.452517071018507 1.636919890768658 0.05617136187561725 12.475626813253172 0.0001383318899534321 3.8590776894909196 -1.0218861817982436 LGAGGGS(ph)PEKSPS(ph)AQELK ddPTM_PC-9_AZD4547_30min_R2 1 LGAGGGSPEKSPSAQELK 18 1 Q9UNE7;H3BS86 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 2 LGAGGGS(1)PEKS(0.029)PS(0.971)AQELK 165.16 2.1084000000000003e-18 0.0 30044.0 30610.0 23410.0 23073.0 27043.0 25059.0 26709.0 25452.0 28300.0 26415.0 True False 39597.36704597875 40504.083888825066 23099.56810417774 17753.87632429647 23288.546246158712 23492.056768598657 29086.049257810995 21518.978228775508 29795.88022440494 25490.21889010027 1.5534337785289607 1.589004945914991 0.906213014637901 0.6964976017209333 0.913626765880907 0.9216106330778647 1.1410670651050099 0.8442053134793955 1.1689142550273224 1.0 14.637656141701493 -5.260611956531305 24.99942764880828 0.9390503935528679 1.5712194241287742 0.7865768912573647 0.12955767166587356 29.945914085914662 904737.1119084796 0.034276409930822434 0.08055962228189222 5.4876707101525894e-06 5.260611956531305 0.6321690305759063 LGAGGGS(ph)PEKSPSAQELK ddPTM_PC-9_AZD4547_30min_R2 4 LGAGGGSPEKSPSAQELK 18 1 Q9UNE7;H3BS86 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 LGAGGGS(0.704)PEKS(0.295)PSAQELK;LGAGGGS(0.772)PEKS(0.218)PS(0.01)AQELK;LGAGGGS(0.889)PEKS(0.11)PSAQELK;LGAGGGS(0.999)PEKS(0.001)PSAQELK 168.68 4.6038999999999996e-07 889839000.0 172829.0 141247.0 165291.0 208736.0 198471.0 197450.0 188136.0 174879.0 167280.0 182922.0 True False 227785.0269334799 186902.33051437046 163099.13334077902 160615.140139052 170916.7275088325 185103.4202865165 204879.73953227536 147855.46886963808 176122.0792911114 176517.95645712333 1.2904354407071865 1.0588289954499304 0.9239804075139303 0.9099082232920923 0.9682682200683 1.0486379063167923 1.1606736427522668 0.8376228222739058 0.9977572980451533 1.0 17.429455424924534 -4.80167262509174 3.142744893066428 0.9811176349818216 1.3293855029325077 0.5641494393125779 0.08177377954705675 0.253613027674394 3.8689852899212913 0.021798447883067982 0.21552405565430732 1.578800934949605e-05 4.80167262509174 0.3482678679506861 LGAGGGS(ph)PEKSPSAQELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LGAGGGSPEKSPSAQELK 18 1 Q9UNE7;H3BS86 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 LGAGGGS(0.961)PEKS(0.036)PS(0.004)AQELK;LGAGGGS(0.997)PEKS(0.003)PSAQELK;LGAGGGS(0.999)PEKS(0.001)PSAQELK;LGAGGGS(0.789)PEKS(0.169)PS(0.042)AQELK;LGAGGGS(1)PEKSPSAQELK;LGAGGGS(1)PEKSPSAQELK 203.06 2.4505e-19 499733000.0 444945.0 368946.0 356869.0 500533.0 490394.0 442527.0 492657.0 481949.0 412483.0 340162.0 True False 520265.40043566964 405572.5206008297 365378.1103932193 472489.7587598797 394304.8160227846 419320.10509573895 445988.96243219555 469298.34941717616 418514.7835338302 401830.67787908966 1.2947378810938293 1.0093119886751551 0.9092837618116382 1.1758429228294294 0.9812710619905194 1.0435243702869093 1.1098927657444637 1.1679007483803598 1.0415202386806335 1.0 18.616228185682004 -7.261755807800825 23.813960975780613 1.0938201623578379 1.0598920796725564 0.0 0.10843029734124607 82.92679372701676 6240899.645167411 0.04302564021923965 0.031024031741899695 5.473236218603411e-08 7.261755807800825 -0.03392808268528147 LGAGGGS(ph)PEKSPSAQELK ddPTM_PC-9_Lapatinib_30min_R1 3 LGAGGGSPEKSPSAQELK 18 1 Q9UNE7;H3BS86 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 LGAGGGS(0.997)PEKS(0.003)PSAQELK;LGAGGGS(0.984)PEKS(0.002)PS(0.014)AQELK;LGAGGGS(0.99)PEKS(0.005)PS(0.005)AQELK 200.33 2.9039999999999995e-14 299786000.0 70686.0 67748.0 66510.0 69748.2 78422.0 79459.0 54060.3 63773.1 76647.0 67187.4 True False 69678.00467777535 67591.13366842488 61041.80453602452 74877.71530117432 73809.37214358423 76060.72379797579 56859.277814920606 66736.23104114775 68014.20773130837 78800.65256841679 0.8842313154358599 0.8577484001130637 0.7746357745327862 0.9502169444112601 0.9366594024015348 0.9652296182691873 0.7215584638154348 0.8468994718439116 0.863117315840204 1.0 16.265919956608265 -12.117753705450903 1.9694840816995858 2.985422336794908 0.866289349103823 0.23548848155076796 0.07205085943140824 2307175.679897698 88021.57903249028 20598299.596463773 0.01973114471517962 7.625113183934407e-13 12.117753705450903 -2.119132987691085 LGAGGGS(ph)PEKSPSAQELKEQGNR ddPTM_PC-9_Lapatinib_30min_R1 1 LGAGGGSPEKSPSAQELKEQGNR 23 2 Q9UNE7;H3BS86 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 LGAGGGS(0.804)PEKS(0.18)PS(0.016)AQELKEQGNR 79.462 0.00062446 4782600.0 151960.0 6085.8 8937.1 6942.0 4513.2 6451.9 516.18 1194.7 9089.5 1544.6 True False 149793.02253394914 6071.70870401044 8202.326136203646 7452.53783783313 4247.742449292596 6175.967277113482 542.9052747118623 1250.2101234667766 8065.744793321692 1811.5820519498716 82.68630304253759 3.351605684917909 4.5277143960303565 4.113828479263025 2.3447695591378794 3.4091568032847666 0.2996857217300832 0.690120617016011 4.452320989071534 1.0 10.823034435890955 -4.761419203803298 8.644834242781828 2.673742827880887 83.37982215149927 0.9962476487909935 1.4729535567037035 0.004760999420139284 4.158549387277326 0.38932311456317403 2.2441745703835125 1.732131246678332e-05 4.761419203803298 80.70607932361838 LGAGGGSPEKS(ph)PSAQELK ddPTM_PC-9_AZD4547_30min_R2 1 LGAGGGSPEKSPSAQELK 18 1 Q9UNE7;H3BS86 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 LGAGGGS(0.005)PEKS(0.598)PS(0.397)AQELK 110.93 0.0010319 138020000.0 25755.0 21427.0 21741.0 28143.0 28174.0 25071.0 24691.0 26556.0 24826.0 25987.0 True False 33944.55426272077 28352.858722177552 21452.70013468295 21655.06615501564 24262.52641863978 23503.306406701686 26888.451167195002 22452.380396171695 26138.251676716478 25077.2030398272 1.3536020826888304 1.1306228480563805 0.855466221676003 0.863535942211076 0.9675132581614638 0.9372379515121412 1.0722268797078849 0.8953303269313246 1.0423112830886339 1.0 14.614088827147485 -4.93727092364446 3.1747844756005237 0.9519417670611436 1.3573912500032523 0.7659684420936494 0.06895648593522685 0.12666914309141175 2.339168016244786 0.018093143033398727 0.10607790275376631 1.155391255675333e-05 4.93727092364446 0.4054494829421087 LGAGGGSPEKS(ph)PSAQELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGAGGGSPEKSPSAQELK 18 1 Q9UNE7;H3BS86 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 LGAGGGS(0.077)PEKS(0.645)PS(0.279)AQELK;LGAGGGS(0.005)PEKS(0.935)PS(0.06)AQELK 67.32600000000001 0.006174300000000001 298471000.0 158235.0 149060.0 133808.0 203120.0 183320.0 158164.0 194201.0 177570.0 138396.0 162421.0 True False 185021.06021629216 163857.6916967788 136998.49018966596 191739.84492392547 147399.76197363128 149869.60140819085 175804.87538651674 172908.9756509666 140419.77968049096 191866.64157607115 0.9643211487752816 0.8540186577029996 0.714029750374032 0.9993391417543762 0.7682406944887828 0.7811133825927247 0.9162868226721618 0.901193528122562 0.7318613518589026 1.0 17.549744377131184 -10.658660350105214 4.924893038000482 1.0000084374601081 0.8478069239036399 0.19464720534928015 0.09286243076598862 8.305668157077345e-06 1.4575065066000694e-06 0.08680572955498134 0.021052315037622 2.1945205391883536e-11 10.658660350105214 -0.15220151355646827 LGAGGGSPEKS(ph)PSAQELK ddPTM_PC-9_Lapatinib_30min_R1 1 LGAGGGSPEKSPSAQELK 18 1 Q9UNE7;H3BS86 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 LGAGGGS(0.285)PEKS(0.694)PS(0.021)AQELK 89.44 0.006950100000000001 179090000.0 19634.0 14720.0 21008.0 18962.0 28692.0 23867.0 19800.0 18052.0 21770.0 20568.0 True False 19354.015559565363 14685.91674439411 19280.80333322511 20356.528735377673 27004.39297064238 22846.26404669438 20825.147117855933 18890.761822065997 19318.03335173697 24123.151394862718 0.8023004640963703 0.6087893121427589 0.7992655278584855 0.8438585988277142 1.1194388547589704 0.9470679710429433 0.8632846835381082 0.7830967651303214 0.8008088593205509 1.0 14.55813076957165 -5.672636298497596 2.8501337626308705 0.9099573189674306 0.7065646505049998 0.38883116745273805 0.10318221431533799 0.28082795574346886 4.581675764964484 0.03177149456080247 0.06038930965929797 2.125023325595134e-06 5.672636298497596 -0.20339266846243076 LGAGGGSPEKSPS(ph)AQELK ddPTM_PC-9_AZD4547_30min_R2 2 LGAGGGSPEKSPSAQELK 18 1 Q9UNE7;H3BS86 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 LGAGGGSPEKS(0.058)PS(0.942)AQELK;LGAGGGS(0.001)PEKS(0.259)PS(0.74)AQELK 77.324 0.0023514 33010000.0 83808.0 86892.0 91953.0 99805.0 105164.0 88896.0 91335.0 105093.0 101778.0 89692.0 True False 110457.20068530801 114978.13973432813 90733.64313897703 76796.4992218788 90563.7938627752 83337.3190670558 99463.63806065997 88853.29164689238 107157.77729609486 86551.91038012011 1.2761959868961903 1.3284298316393621 1.0483147366764236 0.8872883207846327 1.046352338903158 0.9628593834734968 1.149179002795362 1.0265896068228306 1.2380752409216338 1.0 16.40127804276365 -5.266140193112815 23.764104069077728 1.0410087170101388 1.3023129335032102 0.5589450963343756 0.09143798590130278 128.27450271582705 648476.2925816667 0.024019533338620162 0.05288393987607174 5.418259571886453e-06 5.266140193112815 0.26130421649307145 LGAGGGSPEKSPS(ph)AQELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGAGGGSPEKSPSAQELK 18 1 Q9UNE7;H3BS86 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 LGAGGGSPEKS(0.249)PS(0.751)AQELK;LGAGGGS(0.005)PEKS(0.407)PS(0.588)AQELK 68.48100000000001 0.005635899999999999 16060500.0 60178.0 63888.0 55232.0 71722.0 79596.0 62066.0 77202.0 57489.0 57401.0 50343.0 True False 70364.9468303221 70230.37841891733 56548.940348526456 67703.64886586118 63999.73518466683 58811.1496990515 69888.86766592273 55979.97466463052 58240.38103297693 59469.787385031275 1.183204950351532 1.1809421473834718 0.950885194567889 1.1384545303234495 1.076172254834322 0.9889248353669824 1.1751995549174263 0.9413178880595906 0.9793272112426656 1.0 15.859869297383806 -1.5228787452803376 0.31480532213561907 1.0048808503628668 2.7138409122458005 0.33381695222113716 0.077699745928868 69.24449150798034 0.9887243048976043 0.07509979870440218 67.74773686095018 0.029999999999999995 1.5228787452803376 1.7089600618829337 LGAGGGSPEKSPS(ph)AQELK ddPTM_PC-9_Lapatinib_30min_R1 3 LGAGGGSPEKSPSAQELK 18 1 Q9UNE7;H3BS86 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 LGAGGGSPEKS(0.143)PS(0.857)AQELK;LGAGGGS(0.023)PEKS(0.213)PS(0.764)AQELK;LGAGGGS(0.012)PEKS(0.319)PS(0.669)AQELK 154.52 8.542700000000001e-05 25983200.0 72947.0 81019.0 70023.0 72525.0 77609.0 76506.0 69133.0 82736.0 82689.0 66605.0 True False 71906.76240315862 80831.40548329258 64265.97923659668 77858.73043630763 73044.19120516459 73234.0167241966 72712.36846963307 86580.2166026175 73375.69406622778 78117.58550441629 0.9204939187360501 1.0347401927664912 0.822682611368774 0.996686340643567 0.935054389271096 0.9374843865349166 0.9308066551227747 1.108331959360454 0.9392980286376051 1.0 16.253359737956984 LGAPENSGIST(ph)LER ddPTM_PC-9_AZD4547_30min_R2 3 LGAPENSGISTLER 14 0 C9JME2;Q9Y4F1;Q9Y4F1-2;A0A1B0GV68;M0QYB0;Q9Y4F1-3 C9JME2 FARP1 FERM, RhoGEF and pleckstrin domain-containing protein 1 1 LGAPENSGIS(0.008)T(0.992)LER;LGAPENSGIS(0.001)T(0.999)LER;LGAPENS(0.004)GIS(0.102)T(0.893)LER 190.18 5.66e-06 73910300.0 79605.0 110405.0 127489.0 162616.0 146112.0 129980.0 124118.0 159145.0 128859.0 138885.0 True False 104917.73411313872 146091.25716255262 125798.41256016718 125127.39359215522 125826.87087670511 121852.33005237444 135164.26155157358 134552.7970382872 135670.22366913754 134022.67842330382 0.7828356763753176 1.090048780409617 0.9386352671063571 0.9336285102208352 0.9388476066661445 0.9091918732403634 1.0085178355014226 1.003955439640663 1.0122930332777713 1.0 17.032117619004296 -7.278551782537991 23.58205553504059 1.0065212153860268 0.9400328786934473 0.20913014593856882 0.0694965353960357 707.257433870327 974642.5293082454 0.02774676768648706 0.018770437095777987 5.265604274027173e-08 7.278551782537991 -0.06648833669257947 LGAPENSGIST(ph)LER ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LGAPENSGISTLER 14 0 C9JME2;Q9Y4F1;Q9Y4F1-2;A0A1B0GV68;M0QYB0;Q9Y4F1-3 C9JME2 FARP1 FERM, RhoGEF and pleckstrin domain-containing protein 1 1 LGAPENSGIS(0.033)T(0.967)LER;LGAPENSGIS(0.082)T(0.918)LER;LGAPENSGIS(0.001)T(0.999)LER;LGAPENSGIS(0.002)T(0.998)LER;LGAPENSGIS(0.185)T(0.814)LER;LGAPENS(0.002)GIS(0.061)T(0.936)LER 187.56 1.0423e-05 79589800.0 133795.7 165147.0 198171.0 169191.0 301162.0 189465.0 188906.0 197450.0 162887.0 152426.0 True False 156444.66942446958 181541.7027414999 202896.14820770314 159711.77679462268 242151.46800950586 179529.12186592966 171011.45611899695 192267.146715568 165268.914223071 180059.6271964476 0.8688492354468014 1.0082310264001344 1.1268275480007552 0.8869938213321683 1.3448404385804664 0.9970537241536152 0.9497490291503327 1.0677970942692323 0.9178565833792396 1.0 17.458115212189185 -10.780668308262435 14.221096654350749 1.0000000146703145 1.026061417176171 0.0 0.1327638679619338 0.0 0.0 0.12514310831367217 0.030351661993846004 1.6570350382512836e-11 10.780668308262435 0.026061402505856535 LGAPENSGIST(ph)LER ddPTM_PC-9_Lapatinib_30min_R1 2 LGAPENSGISTLER 14 0 C9JME2;Q9Y4F1;Q9Y4F1-2;A0A1B0GV68;M0QYB0;Q9Y4F1-3 C9JME2 FARP1 FERM, RhoGEF and pleckstrin domain-containing protein 1 1 LGAPENSGIS(0.001)T(0.999)LER;LGAPENSGIS(0.034)T(0.966)LER 211.45 4.6126000000000004e-11 66390000.0 165890.0 160854.0 107434.0 106385.0 109091.0 81054.0 75352.0 82465.0 125885.0 64252.0 True False 163524.37817950008 160481.5524458405 98601.19122723298 114208.90778995621 102674.48186115816 77587.5093661024 79253.35785983232 86296.62495328361 111706.50567218219 75357.87258959167 2.169970735109179 2.129592396004104 1.3084391562408788 1.5155537685087277 1.3624917786670563 1.029587310521007 1.051693142818083 1.1451573934851602 1.4823468581783046 1.0 16.201470616690052 -5.119288302927115 0.9282467441576913 1.1682283431264744 2.5506255901041777 0.8010196068845694 0.18035641921251322 0.576607605564882 0.5581991268615274 0.0658556581236224 0.7224973021011513 7.598217079025301e-06 5.119288302927115 1.3823972469777033 LGAQT(ph)PVGVSTLEPGQTLLPR ddPTM_PC-9_AZD4547_30min_R2 2 LGAQTPVGVSTLEPGQTLLPR 21 0 O94887-3;O94887-2;O94887;C9JWM9;C9JVQ5 O94887-3 FARP2 FERM, RhoGEF and pleckstrin domain-containing protein 2 1 LGAQT(0.992)PVGVS(0.004)T(0.004)LEPGQT(0.001)LLPR;LGAQT(0.982)PVGVS(0.014)T(0.003)LEPGQT(0.001)LLPR 98.70299999999999 0.00071626 3007600.0 18789.0 19267.1 27950.4 39787.0 35336.0 28980.7 28684.4 45920.0 31680.0 35491.0 True False 24763.511164521875 25494.813286324137 27579.75943353308 30614.7218530223 30430.206343758604 27168.532247644664 31237.256030954122 38824.11913662465 33354.540123998166 34248.47089261967 0.7230545048905601 0.7444073449661108 0.8052844029155283 0.8939004006634229 0.8885128459944214 0.7932772336851778 0.9120773925613582 1.1336015338714291 0.9738986662667576 1.0 15.063751956385218 -6.566468629140602 0.45184604813352397 1.0477902515976973 0.7053753651680301 0.6715379927832208 0.06888923261376187 0.8373683289538031 0.34570565242743756 0.07019538943537994 0.12402373963758985 2.7135096529265545e-07 6.566468629140602 -0.3424148864296672 LGAQT(ph)PVGVSTLEPGQTLLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGAQTPVGVSTLEPGQTLLPR 21 0 O94887-3;O94887-2;O94887;C9JWM9;C9JVQ5 O94887-3 FARP2 FERM, RhoGEF and pleckstrin domain-containing protein 2 1 LGAQT(0.999)PVGVSTLEPGQTLLPR;LGAQT(0.996)PVGVS(0.001)TLEPGQT(0.003)LLPR 157.7 7.7746e-06 7751700.0 28988.5 30348.7 34802.0 37648.0 52750.0 35294.6 37886.0 35141.0 31732.6 25058.7 True False 33895.680501026814 33361.518368429046 35631.81166731997 35538.70461646285 42414.01616904342 33443.68904340771 34297.16380911301 34218.585984967205 32196.629242818846 29601.64394543996 1.1450607460687445 1.1270157302722468 1.2037105686763365 1.2005652348891749 1.4328263743465899 1.129791612420215 1.1586236180776839 1.1559691092845021 1.087663553489185 1.0 14.853389678581893 -8.34232700078776 1.024164164631867 1.0025290764754446 1.208651577743864 0.38713631939274584 0.08243991978309999 0.5649097885007827 1.2615272763276988 0.08274630203244727 0.027990811675436215 4.546456071324346e-09 8.34232700078776 0.20612250126841936 LGAQT(ph)PVGVSTLEPGQTLLPR ddPTM_PC-9_Lapatinib_30min_R1 1 LGAQTPVGVSTLEPGQTLLPR 21 0 O94887-3;O94887-2;O94887;C9JWM9;C9JVQ5 O94887-3 FARP2 FERM, RhoGEF and pleckstrin domain-containing protein 2 1 LGAQT(0.737)PVGVS(0.004)T(0.001)LEPGQT(0.257)LLPR 140.51 1.2834e-10 0.0 10863.0 9614.8 11619.0 9838.9 7955.5 8000.5 6374.0 7681.6 9450.8 8123.6 True False 10708.091627969783 9592.537521331546 10663.730670637025 10562.485527608236 7487.573131114787 7658.337265076399 6704.014531778472 8038.515179059508 8386.351382664025 9527.753435983406 1.1238842083726266 1.0067995132098475 1.1192282359410541 1.1086018964047668 0.7858697416367344 0.8037925536730626 0.7036301450097839 0.843694710727977 0.8802023938813681 1.0 13.217920363556109 -6.259934763455599 24.978050506090174 0.8201342972555127 1.0858263895346112 0.7148146073900965 0.07801110870579715 68.54685712524773 1137942.594550159 0.023129919289447184 0.028291943752541942 5.496234280733012e-07 6.259934763455599 0.2656920922790985 LGAS(ph)NSPGQPNSVK ddPTM_PC-9_Lapatinib_30min_R1 1 LGASNSPGQPNSVK 14 0 P49756 P49756 RBM25 RNA-binding protein 25 1 LGAS(0.68)NS(0.187)PGQPNS(0.132)VK 156.72 0.00036606 240960000.0 162740.0 158710.0 175820.0 157830.0 154030.0 180540.0 177830.0 146080.0 159670.0 112280.0 True False 160419.29775713914 158342.5167461135 161364.75828482665 169437.34470544558 144970.2582346313 172818.72505929554 187037.16727112755 152867.41009125896 141686.2832003602 131687.44839630395 1.2181821404449173 1.202411609264332 1.2253617201178577 1.2866628275425005 1.1008661797315238 1.3123401445155953 1.4203112714907542 1.160835083015774 1.0759285332491633 1.0 17.006758318137877 -8.222159272358065 2.8787519793558687 1.0201713283833864 1.2484686208646314 0.5276039649885471 0.0802718098603854 0.21940301009445307 3.3523037528065704 0.074405672326427 0.022056067028317947 5.995711503114579e-09 8.222159272358065 0.22829729248124497 LGASEAAAFDS(ph)DESEAVGATR ddPTM_PC-9_AZD4547_30min_R2 1 LGASEAAAFDSDESEAVGATR 21 0 H0YBE8;H3BLZ3;Q8IX03;Q8IX03-2 H0YBE8 WWC1 Protein KIBRA 1 LGASEAAAFDS(0.969)DES(0.031)EAVGATR 128.74 1.6091999999999998e-06 0.0 2494.7 2280.6 3123.7 4597.6 3592.0 2781.9 3393.8 3160.3 2489.1 3835.1 True False 3287.9627070164825 3017.759350436278 3082.277697010679 3537.694352211915 3093.3128024332364 2607.947353228965 3695.8416253382393 2671.948251469403 2620.668744401637 3700.834316313592 0.8884382347307103 0.8154267639417789 0.8328602238213522 0.9559180578869629 0.8358420123801952 0.7046917344375325 0.9986509282641094 0.7219853749440305 0.7081291731568492 1.0 11.853634833328245 -6.514685829544665 24.80895880993026 0.8145301006329513 0.8698735578083322 0.035503765478907656 0.10598700699902058 1182.798967903581 3581641.6335253394 0.03355293077608616 0.035117213109612445 3.057131855534951e-07 6.514685829544665 0.05534345717538092 LGASEAAAFDS(ph)DESEAVGATR ddPTM_PC-9_Lapatinib_30min_R1 2 LGASEAAAFDSDESEAVGATR 21 0 H0YBE8;H3BLZ3;Q8IX03;Q8IX03-2 H0YBE8 WWC1 Protein KIBRA 1 LGASEAAAFDS(1)DESEAVGATR;LGAS(0.004)EAAAFDS(0.897)DES(0.098)EAVGATR 157.73 3.8835999999999994e-23 0.0 10356.5 9076.599999999999 10452.8 7598.0 8866.400000000001 8796.5 10905.400000000001 10849.7 11529.2 7727.4 True False 10208.8144108505 9055.583690364645 9593.411132974843 8156.782266184985 8344.895784013095 8420.294200643031 11470.028251467993 11353.816670777167 10230.660088141749 9063.070793886722 1.126418919483296 0.9991738888846453 1.0585166276584588 0.9000020469537707 0.9207580933431465 0.9290773946423038 1.2655785784223188 1.2527560392042412 1.128829325160143 1.0 13.145784238740767 -7.256775428882847 24.995277269976373 1.1828539906690925 0.9854677961068458 0.4419718798538189 0.09388649595234214 333.3779398531676 1786661.3259674595 0.037264790689489756 0.027874559803074864 5.53636317288016e-08 7.256775428882847 -0.1973861945622467 LGASNS(ph)PGQPNSVK ddPTM_PC-9_AZD4547_30min_R2 4 LGASNSPGQPNSVK 14 0 P49756 P49756 RBM25 RNA-binding protein 25 1 LGAS(0.002)NS(0.918)PGQPNS(0.081)VK;LGAS(0.013)NS(0.987)PGQPNSVK;LGAS(0.007)NS(0.99)PGQPNS(0.003)VK;LGAS(0.002)NS(0.862)PGQPNS(0.136)VK 227.91 1.3454999999999999e-20 1503750000.0 664212.0 659796.0 824656.0 859552.0 829059.0 793672.0 695814.0 812288.0 668908.0 719512.0 True False 875417.5995321422 873062.1539859927 813720.5226193425 661395.5663460187 713958.4684500268 744043.5643739655 757740.0980296722 686767.5541213102 704265.1112772526 694322.1038824089 1.2608234631118755 1.2574310238780118 1.1719640179526174 0.9525774314942929 1.0282813473139025 1.0716115189384456 1.091338002625369 0.9891195315274334 1.0143204534887278 1.0 19.405245575090312 -5.572634048509146 4.462475081417338 1.0263736487145803 1.2514325167256417 0.8687351305598959 0.03809877303828256 0.07053486631417549 2.994458764571246 0.011377155653210713 0.021015261604635634 2.675259725169633e-06 5.572634048509146 0.22505886801106145 LGASNS(ph)PGQPNSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 LGASNSPGQPNSVK 14 0 P49756 P49756 RBM25 RNA-binding protein 25 1 LGAS(0.001)NS(0.999)PGQPNSVK;LGAS(0.001)NS(0.999)PGQPNSVK;LGAS(0.066)NS(0.905)PGQPNS(0.029)VK;LGAS(0.006)NS(0.984)PGQPNS(0.01)VK;LGASNS(0.991)PGQPNS(0.009)VK;LGAS(0.003)NS(0.997)PGQPNSVK;LGAS(0.022)NS(0.829)PGQPNS(0.149)VK 206.49 8.2743e-11 1094215000.0 1052903.0 1176346.0 1110543.0 1133908.0 1232730.0 949052.0 1112902.0 935321.0 897970.0 749598.0 True False 1231138.6821178268 1293125.8566801222 1137022.5568777819 1070378.8109393388 991185.4057263469 899282.042409439 1007479.865847264 910769.8148045145 911101.1124576624 885494.1835854966 1.3903407892898456 1.4603437048497199 1.284054235425703 1.2087925937641024 1.1193584600554811 1.0155708067647755 1.137760003987637 1.0285440962657406 1.0289182349775348 1.0 19.75612330502787 -5.815483213630725 1.0384614488297659 1.044090540610331 1.450540364517826 0.9207103080934051 0.043945163078294186 0.14792040737124745 0.3094779636303377 0.016773773697197514 0.045416148315463895 1.5293848591267027e-06 5.815483213630725 0.4064498239074952 LGASNS(ph)PGQPNSVK ddPTM_PC-9_Lapatinib_30min_R1 4 LGASNSPGQPNSVK 14 0 P49756 P49756 RBM25 RNA-binding protein 25 1 LGAS(0.006)NS(0.913)PGQPNS(0.081)VK;LGASNS(0.982)PGQPNS(0.018)VK;LGAS(0.027)NS(0.831)PGQPNS(0.141)VK;LGASNS(0.771)PGQPNS(0.229)VK 167.92 0.0001295 1253530000.0 251444.1 263785.0 276889.2 241282.0 260723.3 252494.7 241060.5 214648.6 246655.0 196081.0 True False 247858.46102479938 263174.22203940194 254124.43879922168 259026.68317315684 245388.06809572983 241696.09027489368 253541.43317191448 224621.95756923943 218874.1165077027 229973.33958849113 1.0777704122934921 1.144368397268656 1.1050169521995288 1.1263335290806016 1.067028328304583 1.0509743899331068 1.1024818512684798 0.9767304243664621 0.9517369139368541 1.0 17.811107096159283 -7.764168238374096 23.950935118828333 0.9731751743118084 1.096755519384009 0.7956710751767357 0.027883237625761705 18.681510769943586 163954.36060375892 0.01536224824151633 0.007912770548566015 1.7212016812552526e-08 7.764168238374096 0.12358034507220061 LGASNS(ph)PGQPNSVKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGASNSPGQPNSVKR 15 1 P49756 P49756 RBM25 RNA-binding protein 25 1 LGAS(0.208)NS(0.787)PGQPNS(0.005)VKR 67.846 0.042601 39235000.0 9920.2 10078.0 10734.0 12433.0 16609.0 15498.0 14646.0 12725.0 13922.0 13945.0 True False 11599.493927118903 11078.477236818317 10989.93926892169 11736.419318329848 13354.58567870412 14685.257597330256 13258.624852142453 12390.982233251985 14125.58291216364 16473.11811144073 0.7041468317441948 0.672518533642044 0.667143839713568 0.7124588823398771 0.8106896088743053 0.891467996403863 0.8048643105966816 0.7521940988601505 0.8574929662134392 1.0 14.007826040754471 -6.257192887192885 2.909488200002521 0.8429858343731431 0.6814796942516791 0.6321517329565915 0.06162378332562552 0.187057333344106 3.1985023458850916 0.019484064037257876 0.024464135039700498 5.531043993234951e-07 6.257192887192885 -0.16150614012146403 LGASNSPGQPNS(ph)VK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGASNSPGQPNSVK 14 0 P49756 P49756 RBM25 RNA-binding protein 25 1 LGASNS(0.132)PGQPNS(0.868)VK;LGAS(0.001)NS(0.28)PGQPNS(0.719)VK 162.64 0.00014471 355429300.0 64406.4 103727.0 69774.2 80956.0 79511.0 55339.2 68549.0 58696.0 46310.7 49198.0 True False 75309.13143561523 114024.33105213854 71437.88154812713 76420.29778289316 63931.39032448921 52437.114932906115 62055.542468217514 57155.29219355267 46987.906376263214 58117.207948846284 1.2958146836974853 1.9619719369949895 1.229203605427939 1.3149340871666948 1.1000423554545233 0.9022648675597134 1.0677653772156033 0.9834486929217199 0.8085024734433409 1.0 15.826677774620862 -5.921263846618775 1.1464591582137105 0.9541122014074757 1.6195429134698465 0.6343542758862223 0.18626304492228649 0.30283841170051784 0.8021169615576091 0.06731490373617798 0.14765656672236754 1.1987707935057893e-06 5.921263846618775 0.6654307120623708 LGASNSPGQPNS(ph)VK ddPTM_PC-9_Lapatinib_30min_R1 1 LGASNSPGQPNSVK 14 0 P49756 P49756 RBM25 RNA-binding protein 25 1 LGAS(0.002)NS(0.324)PGQPNS(0.674)VK 105.14 0.0039427 0.0 7080.7 54410.0 5717.8 17292.0 8111.9 9348.0 6821.9 7821.2 10621.0 9836.7 True False 6979.727919558653 54284.01698794044 5247.704555346273 18563.711364421004 7634.773990609013 8948.207831252323 7175.1046021869415 8184.601504694356 9424.75113591173 11536.960488421142 0.6049884565838402 4.705226913312358 0.4548602346877269 1.6090643097072346 0.6617665023878267 0.7756122455505526 0.6219233054831126 0.7094244201415685 0.8169180387997955 1.0 13.493975563162355 -5.31609336771028 24.99997866493149 0.833088704207132 2.6551273364748362 0.3647008113564183 0.9629040154270384 251.37846513770307 114985.72608636801 0.22806926584985585 0.4747644697172547 4.829549617923837e-06 5.31609336771028 1.8220386322677042 LGCNAGVS(ph)PSFQQHCVASLATK ddPTM_PC-9_AZD4547_30min_R2 1 LGCNAGVSPSFQQHCVASLATK 22 0 G3V4M9;Q13572 G3V4M9 ITPK1 Inositol-tetrakisphosphate 1-kinase 1 LGCNAGVS(0.868)PS(0.131)FQQHCVASLATK 70.572 0.0099231 0.0 9068.3 11794.0 19279.0 32223.0 24541.0 21377.0 10457.0 22035.0 12865.0 17118.0 True False 11951.830767642434 15606.179855759647 19023.347863325183 24794.48519038727 21133.90575849501 20040.29281066018 11387.65274210677 18629.99706392693 13545.017635581955 16518.70403031369 0.7235331988338476 0.9447581255236817 1.1516247175574543 1.5009945783208287 1.2793924825889431 1.213187957958686 0.6893793073118291 1.1278122684284906 0.8199806480414756 1.0 14.011812884564641 -7.229242414822191 24.965812615667858 0.9199439601130527 1.1507837919822022 0.2011225847068726 0.2192814190273862 1144.0854305179312 887135.0773768376 0.09076331768843053 0.0702994608160377 5.898717332129006e-08 7.229242414822191 0.23083983186914947 LGDAS(ph)DTEAADGER ddPTM_PC-9_AZD4547_30min_R2 1 LGDASDTEAADGER 14 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 LGDAS(0.949)DT(0.051)EAADGER 163.62 0.00055809 14845000.0 15060.0 18153.0 25182.0 31766.0 36432.0 28636.0 20798.0 31761.0 25880.0 26202.0 True False 19848.76673254027 24020.602248737076 24848.070226373504 24442.839479807655 31374.045662095694 26845.38639313586 22648.981708935316 26853.067245172842 27247.96396493284 25284.675955268103 0.7850117109531216 0.9500063315516742 0.9827323976915103 0.9667056648481568 1.2408324203007577 1.0617255463597342 0.8957592238478486 1.0620293213438616 1.0776473470784458 1.0 14.625975668763177 -4.443221279697213 1.019646468712749 1.0468796677993737 0.48012942615387405 0.4640194511901711 0.08431278439658105 3.2293361007860635 1.7117693830821252 0.028685660455303574 2.354213762737294 3.6039496947078294e-05 4.443221279697213 -0.5667502416454997 LGDAS(ph)DTEAADGER ddPTM_PC-9_Lapatinib_30min_R1 2 LGDASDTEAADGER 14 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 LGDAS(0.908)DT(0.092)EAADGER;LGDAS(0.986)DT(0.014)EAADGER 160.87 0.00037822 22985500.0 50005.0 49914.0 58699.0 46199.0 52998.0 43437.0 45983.0 46633.0 56102.0 35502.0 True False 49291.919530206105 49798.427199707 53872.99480469252 49596.62857534614 49880.76183807699 41579.30076659257 48363.77474345301 48799.73942213629 49783.20197974955 41638.47339655853 1.1838070781499914 1.1959714931293062 1.293827328673034 1.191125046852591 1.1979488624143386 0.9985788953066935 1.161516520618893 1.171986757472469 1.1956058404356436 1.0 15.345629555209163 -6.547869685307924 24.994479569865355 1.1173941424487153 1.2170666475230913 0.37455286301533997 0.06859958346627686 272.5986917495439 272635.24266743514 0.02282116770104933 0.02282181517674936 2.83224171264816e-07 6.547869685307924 0.09967250507437608 LGDDNLCNTPHLPPCS(ph)PPK ddPTM_PC-9_AZD4547_30min_R2 1 LGDDNLCNTPHLPPCSPPK 19 0 J3KTI7;J3QR52;J3QLN7;Q99741 J3KTI7 CDC6 Cell division control protein 6 homolog 1 LGDDNLCNTPHLPPCS(1)PPK 89.04899999999999 0.00061197 4096100.0 11545.0 13459.0 11478.0 14432.0 12894.0 14209.0 17342.0 14150.0 13702.0 15425.0 True False 15216.069849082172 17809.358544910046 11325.794220408023 11104.92537217729 11103.89066664092 13320.508983798969 18885.404404094443 11963.442634652425 14426.25974681259 14884.975445004598 1.0222435304176931 1.1964654299034716 0.7608876657038062 0.7460492906559751 0.7459797772368774 0.8948962685907107 1.2687561678465777 0.80372605778583 0.969182636552756 1.0 13.861569221185908 -7.048254248157794 24.999582462748794 1.006598051897524 0.8879572114865982 0.10233289662711342 0.16762446926587704 1057.2445215067692 547734.3280368762 0.06917730298880295 0.05358580064738631 8.948407473318992e-08 7.048254248157794 -0.11864084041092571 LGDDNLCNTPHLPPCS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 1 LGDDNLCNTPHLPPCSPPK 19 0 J3KTI7;J3QR52;J3QLN7;Q99741 J3KTI7 CDC6 Cell division control protein 6 homolog 1 LGDDNLCNTPHLPPCS(1)PPK 85.805 0.0028542 0.0 9490.2 16163.0 12431.0 13302.0 17369.0 11468.0 11855.0 11570.0 10786.0 11914.0 True False 9354.868007710465 16125.57556655176 11408.971165047662 14280.273454171178 16347.389568767856 10977.540373213704 12468.793893039505 12107.584438361606 9571.167098384703 13973.319025592884 0.6694807433063342 1.154026150624408 0.8164825510783458 1.0219671810266473 1.1699002605484592 0.7856072242469917 0.8923287209146402 0.8664787811819021 0.684960178813251 1.0 13.77038711848156 LGDLYEEEMR ddPTM_PC-9_Lapatinib_30min_R1 4 LGDLYEEEMR 10 0 P08670;B0YJC4 P08670 VIM Vimentin 0 ;;; 169.65 0.0018736 24841200.0 63879.0 57324.4 68172.0 68667.0 71970.0 72626.0 63299.7 61899.0 66541.0 55785.0 False True 62968.07374602611 57191.66887380061 62567.16131152999 73717.00024639704 67736.86609846416 69519.95527947496 66577.04873818911 64775.05351340923 59046.45187220617 65427.36292115988 0.9624119165845455 0.8741246218759681 0.9562843207806428 1.1266998539315454 1.035298735486057 1.0625516935971677 1.0175719418558045 0.9900300214065377 0.9024733572612009 1.0 15.997606502958499 -5.532253121944103 24.979340550520263 1.0227812915597723 0.9175022997895083 0.34646304862359445 0.05703394149923811 198.43310570226015 528750.9357334413 0.01608155750388074 0.027897798688741635 2.9359379863271217e-06 5.532253121944103 -0.10527899177026401 LGDS(ph)SLSR ddPTM_PC-9_AZD4547_30min_R2 1 LGDSSLSR 8 0 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 LGDS(0.72)S(0.28)LSR 78.264 0.022374 13737000.0 51792.0 54228.0 71831.0 87301.0 59037.0 81426.0 65056.0 82834.0 59543.0 69668.0 True False 68260.77865947704 71756.14051366232 70878.47400645829 67175.10323700465 50840.73160279821 76334.41934793537 70845.85796982849 70033.9086359575 62690.321420556305 67228.94452528884 1.0153480638655583 1.0673399831031192 1.0542850926329304 0.9991991353030398 0.7562327798211076 1.1354398003262034 1.0537999439092653 1.0417225665295629 0.9324900437336885 1.0 16.0367948794077 -5.806941920689875 6.612326912137491 0.9890224551408441 1.0478164381048198 0.0731798063090835 0.09351969510441765 0.5756863429597662 60.95149109551453 0.027558614174456614 0.04177433176065972 1.559761079712244e-06 5.806941920689875 0.058793982963975755 LGDSHDLQR ddPTM_PC-9_AZD4547_30min_R2 4 LGDSHDLQR 9 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 ;;; 143.04 3.3831e-09 19146400.0 146619.0 147491.0 204614.0 277857.0 235632.0 206232.0 165559.0 216859.0 180568.0 182644.0 False True 193240.79213534686 195164.58140629536 201900.68466758748 213801.36149785685 202918.56410438413 193336.2804382313 180293.4302697196 183348.42447407 190112.45584312174 176249.68915250723 1.096403591203712 1.1073187268853635 1.145537819887357 1.2130595096417816 1.1513130325512266 1.0969453697642508 1.022943252476964 1.0402765834975192 1.0786541341279712 1.0 17.427261187502673 -7.022056959165757 3.377457406926364 1.039350804776834 1.1443630162187766 0.6805041190599393 0.03452092012667351 0.16184382770829756 3.8333086783770063 0.014926696240085602 0.011975593683219933 9.50480126851312e-08 7.022056959165757 0.1050122114419425 LGDSHDLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LGDSHDLQR 9 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 ;;; 143.37 0.00051036 17983000.0 148089.0 141094.0 167410.0 164674.0 199430.0 166857.0 166102.0 162291.0 159010.0 130060.0 False True 173157.54280892666 155100.8798622386 171401.6893059607 155447.84966031162 160353.12312023397 158106.72518503916 150367.61608565948 158031.03321152824 161335.22043263438 153638.84844560642 1.1270427015093814 1.0095160269126189 1.1156142540774312 1.011774373688733 1.0437016727380943 1.0290803841908158 0.9787082994109718 1.028587722508717 1.0500939187249425 1.0 17.229183530166416 -1.5228787452955568 0.38208472895016704 1.0147056639804366 2.284525796872576 0.37816478951587873 0.03591063270976098 76.96044729971732 1.047771849812374 0.026466130651083566 72.48603702342018 0.029999999998948694 1.5228787452955568 1.2698201328921392 LGDSHDLQR ddPTM_PC-9_Lapatinib_30min_R1 2 LGDSHDLQR 9 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 ; 89.88600000000001 0.007553399999999999 17586000.0 106167.0 108044.0 123806.0 104498.0 101884.0 102897.0 107233.0 104178.0 105120.0 100352.0 False True 104653.03911135656 107793.83075620362 113627.14858498036 112183.13151510891 95891.38343165084 98496.33517462236 112785.00004490138 109018.4902004871 93280.27863732624 117697.70948936528 0.8891680183530896 0.9158532585202388 0.9654151221629956 0.9531462591907564 0.8147259946491586 0.8368585557183007 0.9582599400975785 0.9262583840710816 0.7925411551509818 1.0 16.844726718853202 LGDSS(ph)LSR ddPTM_PC-9_AZD4547_30min_R2 3 LGDSSLSR 8 0 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 LGDS(0.224)S(0.776)LS(0.001)R;LGDS(0.039)S(0.959)LS(0.003)R;LGDS(0.238)S(0.762)LSR 105.2 0.003846 83787000.0 256651.0 293537.0 355686.0 405210.0 347015.0 388688.0 324331.0 419780.0 332555.0 321717.0 True False 338260.679327569 388417.09482110554 350969.37123889604 311795.09493209264 298837.957164913 364383.2779150444 353195.83068759984 354912.6465847628 350133.17837551143 310453.7857530334 1.0895685440172278 1.251126939486227 1.1305044014444483 1.0043204793776497 0.962584355156291 1.17371182004175 1.1376760306880838 1.1432060515026108 1.1278109478556755 1.0 18.244018998833752 -8.606104186843748 0.009268503646866785 5.011051703757185e-07 2.1726247596333503 0.09304095951384161 0.08045327182849804 6189.3737044982245 34.81429825810365 4135.791521282347 4020.1558662496013 2.4768277976615452e-09 8.606104186843748 2.17262425852818 LGDSS(ph)LSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LGDSSLSR 8 0 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 LGDS(0.226)S(0.774)LSR;LGDS(0.041)S(0.959)LSR;LGDS(0.045)S(0.955)LSR;LGDS(0.043)S(0.957)LSR 117.53 0.0035428000000000005 87936000.0 407572.0 570846.0 603553.0 522772.0 577396.0 458358.0 545112.0 488184.0 447597.0 398328.0 True False 476565.88968606613 627515.8182902157 617943.9925074985 493482.77968969056 464259.39867186634 434320.8995868564 493475.0450908846 475369.68727370386 454142.25935466914 470541.7132372876 1.0128026406146498 1.3336029530154923 1.3132608122159788 1.048754586059056 0.9866487616534579 0.9230231611109778 1.0487381484115779 1.0102604591699218 0.9651477150244734 1.0 18.843963097099568 -5.901158229202498 5.264232717799037 0.9915151622726057 1.2297479208515336 0.5881403605520119 0.08622488164386141 0.13724723547477694 5.990094031289951 0.024431599184270528 0.03683127418483027 1.255572429860243e-06 5.901158229202498 0.2382327585789279 LGDSS(ph)LSR ddPTM_PC-9_Lapatinib_30min_R1 4 LGDSSLSR 8 0 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 LGDS(0.033)S(0.967)LSR;LGDS(0.126)S(0.874)LSR;LGDS(0.035)S(0.965)LSR;LGDS(0.016)S(0.984)LSR 173.39 0.0011794000000000002 101922000.0 705926.0 811036.0 930540.0 780559.0 783433.0 817780.0 799390.0 754075.0 817257.0 604038.0 True False 695859.3657890273 809158.0959719013 854034.5931882755 837963.9127284915 737353.0112285392 782805.455738289 840778.5027546904 789112.0773861286 725208.9105622652 708445.163469959 0.9822346197985365 1.1421605195364044 1.2055055736497946 1.1828211355472462 1.040804637040628 1.1049626648647213 1.1867940471730565 1.113864725282425 1.0236627306624517 1.0 19.434296661452116 -8.289484546819352 3.762969913410643 1.0038001574427706 1.1253024417995854 0.3096027019603811 0.06472981223982162 0.2764252004977679 8.137660929091318 0.06079416382148261 0.01712833134205425 5.134704476186333e-09 8.289484546819352 0.12150228435681476 LGDVISIQPCPDVK ddPTM_PC-9_Lapatinib_30min_R1 2 LGDVISIQPCPDVK 14 0 P55072;C9JUP7;C9IZA5 P55072 VCP Transitional endoplasmic reticulum ATPase 0 ; 177.83 0.00037952 14496700.0 170714.0 189031.0 203395.0 184261.0 185961.0 158872.0 183383.0 159440.0 156216.0 169723.0 False True 168279.58705488697 188593.31033353042 186672.64822740483 197812.1686166766 175023.139593393 152077.41490872065 192877.67444008953 166848.1644643368 138621.3090525926 199059.39440831824 0.8453737516638147 0.9474223052576991 0.9377736166749043 0.9937344037675343 0.8792508392463951 0.7639800942867013 0.9689453492682263 0.8381828195563152 0.6963816476214495 1.0 17.60283943401715 -6.513635250196942 24.71715825005489 0.8473793820843534 0.9331933443538044 0.14272247023338525 0.08916984587605042 697.4912726623245 1865101.4191936953 0.02808848629359577 0.029596478094404022 3.064536157362093e-07 6.513635250196942 0.08581396226945104 LGDVS(ph)PTQIDVSQFGSFK ddPTM_PC-9_AZD4547_30min_R2 3 LGDVSPTQIDVSQFGSFK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 LGDVS(0.983)PT(0.017)QIDVSQFGSFK;LGDVS(1)PTQIDVSQFGSFK;LGDVS(0.986)PT(0.012)QIDVS(0.002)QFGSFK 267.36 3.0379e-78 187800500.0 186337.0 275488.0 250127.0 197545.0 211614.0 269305.0 263241.0 334903.0 264523.0 225075.0 True False 245588.2899496255 364534.1085385377 246810.15254992133 152004.05228982572 182235.04882352613 252465.31577746317 286668.9390346112 283151.43665533577 278505.14574559237 217195.19275749804 1.1307261769086612 1.6783709800867737 1.1363518198374163 0.6998499845230953 0.8390381320593708 1.162389059224459 1.3198677898671622 1.3036726690883944 1.2822804326822643 1.0 17.728632646355933 -5.491450880475801 23.64993837464398 1.0877870930177698 1.4052520707046303 0.23460182498630655 0.22669304550296712 514.2855630564341 387005.2799149566 0.06496986137168896 0.13495227239927987 3.22514406856003e-06 5.491450880475801 0.31746497768686055 LGDVS(ph)PTQIDVSQFGSFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGDVSPTQIDVSQFGSFK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 LGDVS(0.961)PT(0.039)QIDVSQFGSFK;LGDVS(0.892)PT(0.108)QIDVSQFGSFK 201.9 2.4651e-15 121674000.0 96290.0 206723.0 138934.0 124668.0 131777.0 75502.0 117975.0 77278.0 76442.0 76409.0 True False 112589.99518581084 227245.09325528744 142246.71347012924 117683.25613910929 105956.2428191098 71542.54220632538 106799.55393496585 75249.53438280913 77559.81963594402 90261.34684668896 1.2473777438425289 2.517634637573807 1.5759427311863476 1.3038056737508814 1.173882802780231 0.7926154960643572 1.183225795604041 0.8336850380775089 0.8592805486016203 1.0 16.46182068562635 -5.892313080128925 1.7173859726993397 0.9571290316296266 1.9015580771386962 0.5750275765966013 0.3142637401263517 0.23455780234178467 1.4084981276775157 0.09729529593711173 0.17926749034713027 1.2814064918230798e-06 5.892313080128925 0.9444290455090696 LGDVS(ph)PTQIDVSQFGSFK ddPTM_PC-9_Lapatinib_30min_R1 3 LGDVSPTQIDVSQFGSFK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 LGDVS(0.965)PT(0.035)QIDVSQFGSFK;LGDVS(0.822)PT(0.178)QIDVSQFGSFK;LGDVS(0.998)PT(0.002)QIDVSQFGSFK 247.0 1.603e-53 114407000.0 75255.5 166123.0 147075.0 143466.0 188523.0 166559.0 193154.0 190593.0 149250.0 150777.0 True False 74182.3427698316 165738.35240006642 134983.0612259179 154016.96822854623 177434.44779047853 159435.65983799286 203154.56901021965 199448.64657395423 132439.8933278247 176838.60355227624 0.4194917924009852 0.9372294797106989 0.763312187013594 0.8709465305352088 1.0033694240184732 0.9015885481750098 1.1488134656648314 1.1278569416829516 0.7489308932971381 1.0 17.432073721304896 -4.424662448764939 0.7984946475071484 0.9905463088112012 7.938290494266526e-28 0.5511939556943103 0.1354058700783302 3.3797818351323676 1.1176047704422762 0.05026951810846811 3.3920739698490854 3.7612963387027696e-05 4.424662448764939 -0.9905463088112012 LGDVS(ph)PTQIDVSQFGSFKEDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGDVSPTQIDVSQFGSFKEDTK 22 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 LGDVS(0.495)PT(0.495)QIDVS(0.01)QFGSFKEDTK 72.771 0.00059992 47480000.0 33733.0 34248.0 43917.0 44647.0 53144.0 60527.0 49315.0 50801.0 52749.0 45868.0 True False 39443.33064288034 37647.91510285309 44964.14783614999 42145.573337527 42730.81469739608 57352.85756830615 44643.526190318546 49467.52757810877 53520.3543336963 54183.505309111744 0.7279582673335712 0.6948224351317862 0.8298493716793294 0.7778303211852114 0.788631419352086 1.0584929350936887 0.8239320423370816 0.9129628527335253 0.9877610174603464 1.0 15.725566108794228 -5.771561467375436 0.3516775754183501 0.9954656560843576 0.5984455253931035 0.6307599572553714 0.07109800601044966 2.200526736400928 0.36428768646832316 0.07514213492341155 0.35065543352067385 1.6921487311415484e-06 5.771561467375436 -0.3970201306912541 LGDVS(ph)PTQIDVSQFGSFKEDTK ddPTM_PC-9_Lapatinib_30min_R1 2 LGDVSPTQIDVSQFGSFKEDTK 22 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 LGDVS(0.768)PT(0.232)QIDVSQFGSFKEDTK;LGDVS(0.74)PT(0.26)QIDVSQFGSFKEDTK 83.87899999999999 0.00011307 33653000.0 130296.0 75919.0 85061.5 78679.0 90519.0 83657.0 65427.4 67255.4 79896.0 61087.8 True False 128437.95514664009 75743.21421994957 78068.07181688538 84465.31612544971 85194.85038720122 80079.18512399185 68814.910633273 70380.33141190896 70897.27113782162 71646.74483562312 1.7926558344180363 1.0571759316312954 1.0896248251891207 1.178913519647485 1.189095897973608 1.1176946741644023 0.9604750472774848 0.9823242015164869 0.989539319622671 1.0 16.128613538800515 -4.760864486052633 24.999983100743165 1.0691455303935227 1.792656659141722 0.8889976284497703 0.07734486585305526 4.854825429482832 210938.68623219148 0.02201239530612403 0.12701141831148344 1.734345085182206e-05 4.760864486052633 0.7235111287481992 LGDVSPT(ph)QIDVSQFGSFK ddPTM_PC-9_Lapatinib_30min_R1 1 LGDVSPTQIDVSQFGSFK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 LGDVS(0.176)PT(0.824)QIDVSQFGSFK 126.04 9.219399999999999e-05 7046300.0 12693.0 26781.0 25220.0 23554.0 39859.0 32438.0 35020.0 43212.0 28582.0 26627.0 True False 12511.995492388878 26718.990239919724 23146.508952015316 25286.23973384063 37514.57198580909 31050.70235667127 36833.16424582397 45219.78727316178 25362.794178196888 31229.441471752696 0.4006474308452198 0.8555705443559497 0.7411758859969217 0.8096923461379306 1.2012565776990072 0.9942765830364563 1.17943717562608 1.4479857833532974 0.812143701037297 1.0 14.930619147014303 -5.090083358706757 0.6176299575731586 1.1448702375412951 0.23830947329090602 0.5471738257395204 0.18562089489028305 1.917501393926735 0.718381138344356 0.09516136161468759 1.1696785419429236 8.12674516027625e-06 5.090083358706757 -0.9065607642503891 LGDVSPT(ph)QIDVSQFGSFKEDTK ddPTM_PC-9_AZD4547_30min_R2 1 LGDVSPTQIDVSQFGSFKEDTK 22 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 LGDVS(0.044)PT(0.956)QIDVS(0.001)QFGSFKEDTK 78.554 0.00046283 62240000.0 131720.0 101950.0 144050.0 208410.0 191980.0 172890.0 144140.0 168140.0 128020.0 172860.0 True False 173604.2200537989 134903.34375908907 142139.80287940186 160364.29440240245 165326.89081601717 162079.16096903372 156968.1807638205 142157.82647282403 134786.87584199003 166808.2240144894 1.0407413727917827 0.8087331698188395 0.8521150783732055 0.961369233140884 0.9911195433724925 0.9716497008861812 0.9410098434366513 0.8522231281622892 0.8080349553405838 1.0 17.347830893030157 -10.789921510609338 5.182714472402937 1.0000137491906496 0.9135061109752632 0.10224527848149367 0.07633260396736914 1.263218955712072e-05 1.7864031289299554e-06 0.07698886115377838 0.018669574365324126 1.622103231154584e-11 10.789921510609338 -0.08650763821538632 LGDVSPT(ph)QIDVSQFGSFKEDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGDVSPTQIDVSQFGSFKEDTK 22 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 LGDVS(0.154)PT(0.845)QIDVS(0.001)QFGSFKEDTK;LGDVS(0.106)PT(0.894)QIDVSQFGSFKEDTK 110.77 0.00049032 36941000.0 80237.6 55878.4 80814.9 85714.3 96215.8 106113.4 117328.0 95221.2 96086.6 80715.0 True False 93820.24091516239 61425.638264519606 82741.83370821495 80912.00566050995 77363.00468089954 100548.62650203542 106213.84245884026 92721.74439520107 97491.68474701201 95347.99056041171 0.9839771175431186 0.6442258290236418 0.8677879126963919 0.8485968627649764 0.8113753024704068 1.0545437393180157 1.1139599464505132 0.9724561980826782 1.0224828459834407 1.0 16.540914913902093 -6.760445907225452 24.999175465644814 1.0360465426627878 0.8238055132602649 0.5823891866114229 0.0851745832716463 18.048868958091703 454175.51041723037 0.027944534186247212 0.026444877988694635 1.7360174759663598e-07 6.760445907225452 -0.21224102940252298 LGDVSPT(ph)QIDVSQFGSFKEDTK ddPTM_PC-9_Lapatinib_30min_R1 1 LGDVSPTQIDVSQFGSFKEDTK 22 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 LGDVS(0.29)PT(0.71)QIDVS(0.001)QFGSFKEDTK 99.40899999999999 7.818e-05 29320000.0 133300.0 75748.0 93104.0 97466.0 90002.0 96051.0 73673.0 72898.0 89667.0 64543.0 True False 131399.11755577356 75572.61015994332 85449.34851183314 104633.9747770448 84708.2593107401 91943.12263581691 77487.42745524237 76285.10720723281 79567.75822463015 75699.17155185848 1.7358065466510062 0.9983281007001713 1.1288016336254778 1.3822340804002622 1.1190117087702849 1.2145855859575734 1.023623189880735 1.0077403179369397 1.0511047425416202 1.0 16.20798989106078 -4.754890250718935 24.99803609918343 1.114133883486697 1.7358075915288576 0.7312133463901498 0.11494749903511853 124.44748597778579 474972.65697666176 0.030313622356386516 0.28260411002882657 1.7583679098003096e-05 4.754890250718935 0.6216737080421606 LGDVYVNDAFGTAHR ddPTM_PC-9_AZD4547_30min_R2 3 LGDVYVNDAFGTAHR 15 0 P00558;P00558-2;P07205 P00558 PGK1;PGK2 Phosphoglycerate kinase 1;Phosphoglycerate kinase 2 0 ;; 155.37 1.8310999999999998e-05 12486700.0 73500.0 54562.0 88350.0 123156.0 93814.0 88823.3 71916.0 101931.0 76274.9 95633.0 False True 96871.47110502709 72198.09948193653 87178.42127313561 94764.28694123257 80789.54544751439 83269.16500954841 78316.38468024756 86179.90609136062 80306.63549570537 92284.91777841958 1.049699923205437 0.7823390996055017 0.9446659689555675 1.0268664611997171 0.8754360668283184 0.9023052413557066 0.8486368798451864 0.9338460516189939 0.870203251288855 1.0 16.49380726551113 LGDVYVNDAFGTAHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LGDVYVNDAFGTAHR 15 0 P00558;P00558-2;P07205 P00558 PGK1;PGK2 Phosphoglycerate kinase 1;Phosphoglycerate kinase 2 0 ;;; 176.56 7.7017e-06 43300400.0 202666.0 202103.0 220198.0 252595.0 263606.0 262377.0 247276.0 219536.0 217198.0 181203.0 False True 236973.35096404047 222166.4501878039 225448.35542556518 238442.92107403916 211954.29661150422 248617.48823168944 223852.22715679253 213773.41261761903 220374.10985175442 214053.6694978415 1.1070744618392543 1.0379006849496883 1.0532328455496933 1.1139398900911792 0.9901923060171671 1.1614726755908125 1.0457761723120091 0.9986907167679959 1.0295273627812143 1.0 17.707613042141517 -7.525868440977115 18.34189844803079 1.0129112311439636 1.0747479885643558 0.3184990807172471 0.044404374487688344 4.221281792909669 25863.456558307797 0.01964708866642849 0.011522656968084568 2.9794188357094435e-08 7.525868440977115 0.061836757420392185 LGDVYVNDAFGTAHR ddPTM_PC-9_Lapatinib_30min_R1 4 LGDVYVNDAFGTAHR 15 0 P00558;P00558-2;P07205 P00558 PGK1;PGK2 Phosphoglycerate kinase 1;Phosphoglycerate kinase 2 0 ;;; 214.65 9.9264e-18 67035400.0 316528.0 274630.0 320456.0 278214.0 291915.0 303173.0 279041.0 252868.0 292396.0 240289.0 False True 312014.2526758742 273994.11110821756 294109.34467593225 298674.78565469675 274745.1336269718 290206.99752078124 293488.3776219013 264617.17042001965 259463.28341361866 281822.6334850331 1.1071298597188237 0.9722218110021624 1.0435973187779883 1.05979701474388 0.9748866875220752 1.0297504992131634 1.0413939221013195 0.9389493212370851 0.9206616239621439 1.0 18.104427955159494 -7.762923101395547 24.99920327892359 0.9473540848276342 1.0294840300375236 0.43356049464215185 0.041356267227648326 34.896277721519006 587926.4748575125 0.020197286589206886 0.010522369432592698 1.7261435055340495e-08 7.762923101395547 0.08212994520988948 LGEAS(ph)DSELADADK ddPTM_PC-9_AZD4547_30min_R2 2 LGEASDSELADADK 14 0 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 LGEAS(0.994)DS(0.006)ELADADK;LGEAS(0.579)DS(0.421)ELADADK 181.75 2.7189e-05 5729400.0 19910.2 25790.0 20684.0 18188.0 20438.2 27421.0 22888.4 24045.0 22970.3 21012.0 True False 26241.229442113112 34126.11314906234 20409.71664531449 13995.037601798833 17600.708719011964 25706.36053520667 24925.423259293922 20329.39774913198 24184.463163203138 20276.37627555504 1.2941774745889494 1.6830479315085691 1.0065761439789516 0.6902139421564732 0.8680401507556934 1.26779855462625 1.229283917429749 1.002614938332983 1.192740893862758 1.0 14.307512221416479 -5.27535419648482 24.491471441389514 1.0296341571501262 1.4886126949269325 0.4933793827319396 0.18500131888935273 457.5598417673874 805351.5933724025 0.05232274256359371 0.1098473867609391 5.3045164861864824e-06 5.27535419648482 0.4589785377768063 LGEAS(ph)DSELADADK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGEASDSELADADK 14 0 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 LGEAS(0.854)DS(0.146)ELADADK;LGEAS(0.984)DS(0.016)ELADADK 209.53 4.3579e-11 6348400.0 19777.0 40482.0 28427.0 28997.0 33915.0 17115.800000000003 27897.0 18859.3 18066.4 18344.6 True False 23124.85548644486 44500.78542378238 29104.80748999783 27372.392099542423 27269.59921086459 16218.217317356139 25254.39420321032 18364.26335808009 18330.586921729147 21670.330764226288 1.0671205593511164 2.053535126341724 1.3430716774311766 1.263127563550123 1.2583840785615354 0.7484065422817366 1.1653903430445398 0.8474380736447317 0.8458840393885246 1.0 14.403433553667107 -6.193164506763685 1.2650197504261966 0.9257180681262589 1.556893562318537 0.46296563993338724 0.2593270991324063 0.36880988678073534 1.201293240084101 0.09736662858420633 0.14961215709164008 6.409667382780929e-07 6.193164506763685 0.631175494192278 LGEAS(ph)DSELADADK ddPTM_PC-9_Lapatinib_30min_R1 4 LGEASDSELADADK 14 0 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 LGEAS(0.675)DS(0.325)ELADADK;LGEAS(1)DSELADADK;LGEAS(0.996)DS(0.004)ELADADK;LGEAS(0.979)DS(0.021)ELADADK 189.09 3.1224e-06 12417200.0 33769.4 52361.2 44626.2 44133.8 45865.5 41864.3 47774.7 45388.6 36877.6 37832.6 True False 33287.84216345047 52239.96085846254 40957.20609811361 47379.54687804092 43167.78146504246 40073.86147944979 50248.240202597604 47497.5200552307 32724.05634965621 44371.91450122927 0.7502007190275342 1.177320416431779 0.9230434737491198 1.0677823440935443 0.9728627207159734 0.9031357319130233 1.1324334495687702 1.070441079433587 0.7374948031315987 1.0 15.437359181565867 -8.24301887433167 24.98651349648504 0.8687473472910385 1.005607930704438 0.1364549753140002 0.13104042366716354 1265.4945768449913 1716587.9160846435 0.08261722493124489 0.03110063527045001 5.714538008901592e-09 8.24301887433167 0.13686058341339957 LGEASDS(ph)ELADADK ddPTM_PC-9_AZD4547_30min_R2 1 LGEASDSELADADK 14 0 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 LGEAS(0.273)DS(0.727)ELADADK 136.33 3.2196e-05 0.0 8826.4 10010.0 8322.4 7843.6 8467.2 12320.0 9707.7 9209.7 10511.0 11052.0 True False 11633.011599475007 13245.536743781087 8212.039538240439 6035.379202411991 7291.675434510776 11549.628452417717 10571.666493693212 7786.552482852187 11066.590001368204 10665.072843966995 1.0907578194419512 1.2419546436828892 0.7699937598537655 0.565901357703907 0.6836967305512144 1.0829394811823623 0.9912418460107734 0.7300983872095045 1.037647858882496 1.0 13.380606199074258 -5.261586306986938 24.999999596000883 0.8442298558819259 1.166356247865371 0.3557193491987444 0.16537066468542488 13.786271985780157 2346309.095346045 0.045799177680517215 0.10621435589719963 5.4753727851392945e-06 5.261586306986938 0.32212639198344517 LGEASDS(ph)ELADADKASVASEVSTTSSTSKPPTGR ddPTM_PC-9_Lapatinib_30min_R1 1 LGEASDSELADADKASVASEVSTTSSTSKPPTGR 34 2 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 LGEAS(0.446)DS(0.506)ELADADKAS(0.023)VAS(0.023)EVSTTSSTSKPPTGR 48.533 0.0026585000000000003 5407200.0 22223.0 18405.0 20654.0 18727.0 17806.0 17617.0 11717.0 18559.0 22157.0 12669.0 True False 21906.095944800905 18362.384353299825 18955.907846745606 20104.24605144066 16758.686087942915 16863.56197723279 12323.648928278695 19421.3188929605 19661.445336446315 14858.81976961862 1.4742823645786214 1.2357902335449844 1.275734421754289 1.3530176934070635 1.1278611860013872 1.1349193434402647 0.82938275847968 1.3070566299397939 1.3232171626879463 1.0 13.859031907260452 -6.268134510050119 23.109215912373095 1.121933468997968 1.3234284922417126 0.34416945109365193 0.14457896623381367 244.86639999989117 845190.7457165638 0.04623996976109433 0.05374511713711904 5.393435507080951e-07 6.268134510050119 0.20149502324374446 LGELTMQLHPVADS(ph)SPAGAQIK ddPTM_PC-9_AZD4547_30min_R2 1 LGELTMQLHPVADSSPAGAQIK 22 0 Q8IXM2-2 Q8IXM2-2 BAP18 Chromatin complexes subunit BAP18 1 LGELTMQLHPVADS(0.83)S(0.17)PAGAQIK 118.15 8.424799999999999e-07 9655900.0 39348.0 36684.0 45242.0 55093.0 56064.0 44125.0 44625.0 50795.0 41038.0 42899.0 True False 51859.845510756655 48541.38560528124 44642.06151940232 42392.160028365004 48280.48133508271 41365.856774588625 48596.53854992013 42945.79990298018 43207.18489926254 41397.11906743939 1.252740448587077 1.1725788339570984 1.0783857071473173 1.0240364784637455 1.1662763598701096 0.9992448196020638 1.1739111233985215 1.037410352952771 1.0437244395890062 1.0 15.337242749889048 -5.034241932783217 2.2709370581023482 1.069584509349584 1.2586595621136039 0.5260745524749768 0.05827616243485929 0.2936216555620433 2.5406000162149986 0.014863888895610636 0.08989026947975323 9.241831950212653e-06 5.034241932783217 0.18907505276401992 LGELTMQLHPVADS(ph)SPAGAQIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGELTMQLHPVADSSPAGAQIK 22 0 Q8IXM2-2 Q8IXM2-2 BAP18 Chromatin complexes subunit BAP18 1 LGELTMQLHPVADS(0.5)S(0.5)PAGAQIK;LGELTMQLHPVADS(0.5)S(0.5)PAGAQIK 71.308 0.0011159 11959900.0 34260.9 29310.2 38598.3 42570.0 38661.0 48690.3 44871.0 44078.4 36950.5 30396.8 True False 40060.593686380074 32219.92295163644 39518.62985686789 40184.94091380214 31085.65458031067 46136.8949536256 40620.494042092345 42921.388704925295 37490.83115902185 35907.49921906361 1.1156609220257685 0.8973034505987149 1.1005675893989046 1.1191239097059589 0.865714829948587 1.2848818758486837 1.131253774992121 1.1953321628741538 1.0440947427248743 1.0 15.131997559427894 -6.765973125562865 24.99998761441555 1.1433295647973714 1.022894844474091 0.20451194647050308 0.10846913575872956 173.53306835739517 956888.513671099 0.036103147151230974 0.03291815494526405 1.714063371630869e-07 6.765973125562865 -0.12043472032328029 LGELTMQLHPVADS(ph)SPAGAQIK ddPTM_PC-9_Lapatinib_30min_R1 2 LGELTMQLHPVADSSPAGAQIK 22 0 Q8IXM2-2 Q8IXM2-2 BAP18 Chromatin complexes subunit BAP18 1 LGELTMQLHPVADS(0.854)S(0.146)PAGAQIK;LGELTMQLHPVADS(0.567)S(0.433)PAGAQIK 162.75 2.9133e-07 10091200.0 94779.0 86655.0 96969.0 70957.0 94722.0 81554.0 73727.0 82995.0 86615.0 61681.0 True False 93427.43407966004 86454.35567156729 88996.58313116452 76175.41448561307 89150.63819061704 78066.12553165942 77544.22331101834 86851.25068814344 76859.50660361492 72342.47866523374 1.291460229224345 1.1950704104518806 1.230211969139155 1.0529831973012194 1.2323414933453332 1.0791187552877746 1.0719044293444213 1.200556744676241 1.062439496430359 1.0 16.142555409348205 -1.5228787452803376 0.149089629186075 1.004530623281911 1.9363328965410067 0.5316942292262038 0.06412654027319906 58.791775020652075 0.5775524995859539 0.22756232870383242 11.826776709260882 0.029999999999999995 1.5228787452803376 0.9318022732590958 LGELTMQLHPVADSS(ph)PAGAQIK ddPTM_PC-9_AZD4547_30min_R2 2 LGELTMQLHPVADSSPAGAQIK 22 0 Q8IXM2-2 Q8IXM2-2 BAP18 Chromatin complexes subunit BAP18 1 LGELTMQLHPVADS(0.256)S(0.744)PAGAQIK;LGELTMQLHPVADS(0.229)S(0.771)PAGAQIK 117.53 7.3532e-07 16397300.0 51827.0 56713.0 67072.0 99757.0 85737.0 74773.0 56140.0 81189.0 56676.0 75548.0 True False 68306.90793143207 75044.36816683893 66182.58145593372 76759.56488028627 73833.89747834585 70097.43248966153 61136.35124240929 68643.10558761806 59671.7776536528 72903.08751502162 0.9369549392178691 1.0293716044793866 0.9078158924654166 1.0528986836733085 1.0127677715039496 0.9615152784196968 0.8385975591200058 0.9415665087363304 0.8185082372726324 1.0 16.153692294901198 -7.054451201085561 7.00489827598764 0.8950716470396344 0.9892706937812371 0.31481062262678894 0.061489805748099514 0.27769016500976135 30.20987394611799 0.021995551702764078 0.017165583636491878 8.821629196161056e-08 7.054451201085561 0.09419904674160273 LGELTMQLHPVADSS(ph)PAGAQIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGELTMQLHPVADSSPAGAQIK 22 0 Q8IXM2-2 Q8IXM2-2 BAP18 Chromatin complexes subunit BAP18 1 LGELTMQLHPVADS(0.263)S(0.737)PAGAQIK 87.098 0.00015251 13940000.0 30209.0 34626.0 27552.0 29049.0 39976.0 33010.0 40306.0 36178.0 30115.0 28436.0 True False 35322.78704505299 38063.440444738124 28208.94417154186 27421.47870812869 32142.98977011713 31278.89748921614 36487.92388983027 35228.365833759555 30555.374903017364 33591.22170074786 1.0515481502795885 1.1331365314376374 0.8397713076006946 0.8163287108881243 0.9568865954464976 0.931162842717321 1.086233904050531 1.0487372608116616 0.9096238051483877 1.0 15.035796646379929 -7.223345737722141 24.774010889907466 1.015210269996592 0.9514829753570346 0.07544430414263381 0.09578497272425872 1416.9740235992583 921522.3546930586 0.040288378798245865 0.031206917140157213 5.979353948337831e-08 7.223345737722141 -0.06372729463955729 LGELTMQLHPVADSS(ph)PAGAQIK ddPTM_PC-9_Lapatinib_30min_R1 1 LGELTMQLHPVADSSPAGAQIK 22 0 Q8IXM2-2 Q8IXM2-2 BAP18 Chromatin complexes subunit BAP18 1 LGELTMQLHPVADS(0.082)S(0.918)PAGAQIK 117.53 8.996700000000002e-07 7066900.0 25318.0 18224.0 19700.0 14091.0 22957.0 19029.0 18381.0 17489.0 16151.0 12368.0 True False 24956.960677247425 18181.803447679213 18080.342044199104 15127.299146198033 21606.71439519856 18215.174028765552 19332.678241076275 18301.60278673346 14331.904302430134 14505.792320675917 1.720482420093308 1.2534167762600372 1.246422232202248 1.0428454242127987 1.489523213730373 1.2557172766635054 1.332755758092602 1.2616755005272728 0.9880125115263142 1.0 13.824341478662841 -1.5228787452803865 0.0921626479423179 0.83530908049689 2.5524320314254645 0.38600685681310143 0.16787436614950596 189.50027665282346 1.2568101219497607 2.9736533666453644 41.11364805282773 0.029999999999996623 1.5228787452803865 1.7171229509285744 LGEVVNTHGPVEPDKDNIR ddPTM_PC-9_Lapatinib_30min_R1 1 LGEVVNTHGPVEPDKDNIR 19 1 P30419;K7EN82;P30419-2 P30419 NMT1 Glycylpeptide N-tetradecanoyltransferase 1 0 68.123 0.0039071 3174300.0 12740.0 14883.0 14332.0 10975.0 13918.0 14194.0 15102.0 11110.0 12790.0 13230.0 False True 12558.325263770143 14848.539327908795 13153.678283119873 11782.138111526745 13099.370603840818 13586.955707830068 15883.90766534649 11626.211159049035 11349.455515329159 15516.787872133109 0.8093379485018207 0.9569338351641428 0.8477062644352321 0.7593155367346685 0.8442063339259941 0.875629403443166 1.023659522591831 0.7492666172184236 0.7314307322401346 1.0 13.921542315904032 -10.620048556939107 4.277006286630104 1.000019663657546 0.8485051792920049 0.22147017918603318 0.08731222249210013 59221106.28895533 0.8098900232245299 12156.71719106734 0.02253204830114072 2.398564728937728e-11 10.620048556939107 -0.15151448436554116 LGEWVGLCK ddPTM_PC-9_AZD4547_30min_R2 2 LGEWVGLCK 9 0 P25398 P25398 RPS12 40S ribosomal protein S12 0 ; 91.318 0.027363 2310200.0 18610.5 16909.2 26002.0 37201.0 30249.0 25359.0 19374.800000000003 27939.0 22484.0 24288.0 False True 24528.25187755252 22374.768222571733 25657.19649059501 28624.884199720575 26049.448485746943 23773.29772117378 21099.119666039027 23621.669524350113 23672.45833800424 23437.68451269184 1.0465305079207001 0.9546492619804433 1.0946984322065294 1.2213187776386267 1.111434385578524 1.0143193841652831 0.9002220187157802 1.007849965364908 1.0100169376879045 1.0 14.516542427677232 -6.924717399901973 5.233755646008356 0.9771593366150266 1.0857577762682487 0.35446383239455337 0.06811690420221016 0.2582358127507492 12.697072981212163 0.027531719089053816 0.02411317884241416 1.1892758503152137e-07 6.924717399901973 0.10859843965322202 LGEWVGLCK ddPTM_PC-9_Lapatinib_30min_R1 2 LGEWVGLCK 9 0 P25398 P25398 RPS12 40S ribosomal protein S12 0 ; 143.01 0.0028968 11321400.0 72524.0 66485.0 71263.0 66113.0 75662.0 64895.0 65662.0 63023.0 62560.0 67201.0 False True 71489.7944607273 66331.05806732616 65404.03122313499 70975.17056650289 71211.70991721537 62119.59212763369 69061.65707336647 65951.27865677292 55513.83401399472 78816.6033102961 0.9070397791601903 0.8415873722213691 0.8298255504064717 0.9005103948349312 0.9035115308998951 0.7881536315777615 0.8762323441099713 0.8367688518258877 0.7043418731893353 1.0 16.266211955807947 -6.7480947731509096 24.999755636829946 0.8330931962432979 0.873297058844058 0.04862010725021204 0.07349570073040734 705.0877377579558 1320908.473384718 0.023366277222609085 0.023240425151249824 1.7860977642716186e-07 6.7480947731509096 0.04020386260076003 LGEYEDVSR ddPTM_PC-9_Lapatinib_30min_R1 1 LGEYEDVSR 9 0 K7EK42;A0A494C0X0;Q99426;K7EP07;Q99426-2;K7EL99 K7EK42 TBCB Tubulin-folding cofactor B 0 141.52 0.0032863 7231800.0 41370.0 41227.0 33395.0 38190.0 35266.0 35894.0 35798.0 35398.0 38342.0 34028.0 False True 40780.05621367115 41131.541414479325 30649.39200842787 40998.619998105365 33191.72321562367 34358.89729300075 37651.44527904076 37042.7203067523 34023.52020084056 39909.6944605401 1.0218082790383576 1.030615292110224 0.7679685956686998 1.0272847375126342 0.831670692153289 0.8609160695773407 0.9434160243012599 0.9281634652296709 0.8525126704360171 1.0 15.284451613498836 -5.13982104458562 21.34991792025685 0.9008405645459427 1.026251875198229 0.31232451069040545 0.074019489647157 6.302987028267667 1087.13233224137 0.017486392410372132 0.04626492417226489 7.247345327177265e-06 5.13982104458562 0.12541131065228628 LGFEDGSVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGFEDGSVLK 10 0 P09936;D6RE83;D6R956;D6R974 P09936 UCHL1 Ubiquitin carboxyl-terminal hydrolase isozyme L1;Ubiquitin carboxyl-terminal hydrolase 0 115.71 0.005072699999999999 9350700.0 13842.0 21508.0 16001.0 18594.0 29878.0 46248.0 39483.0 65386.0 39560.0 40482.0 False True 16185.177208038122 23643.1720985799 16382.524524130415 17552.238462561356 24023.620381017605 43822.67346504904 35742.88440783426 63669.6867821936 40138.4901598329 47821.0661446643 0.3384528726121679 0.49440913816217624 0.34257965881754643 0.36703988174299146 0.5023648010762318 0.9163884663817479 0.7474296850619739 1.3314150418475694 0.8393474549147292 1.0 15.545358674058926 -6.816545267143253 1.5873100675788558 1.0225805564481347 0.38096236166892755 0.7817145834655066 0.1482152455090825 0.16272036320992578 0.849295431100791 0.06340418854073605 0.05511001226074934 1.525649365875263e-07 6.816545267143253 -0.6416181947792072 down LGFEDGSVLK ddPTM_PC-9_Lapatinib_30min_R1 2 LGFEDGSVLK 10 0 P09936;D6RE83;D6R956;D6R974 P09936 UCHL1 Ubiquitin carboxyl-terminal hydrolase isozyme L1;Ubiquitin carboxyl-terminal hydrolase 0 ; 118.18 0.0041238 31326000.0 184791.0 146948.0 186420.0 179501.0 150838.0 142484.0 158605.0 142264.0 152601.0 156701.0 False True 182155.84645348086 146607.7509344579 171093.26720200968 192702.10233778192 141966.00539891794 136390.29146642654 166816.79083977488 148874.10480026575 135413.46842023046 183786.55905904234 0.9911271389272944 0.7977065988125902 0.9309346019533731 1.0485103117680952 0.772450423609654 0.74211243828016 0.9076658907694342 0.8100380439270274 0.7367974519656153 1.0 17.487671735688792 -6.2876280257541435 24.934910907329503 0.8183504544528796 0.9309626881132692 0.248693921802981 0.09529283700123699 1049.501464427363 999255.3288718249 0.029201355873459497 0.033121748990052644 5.156701281673004e-07 6.2876280257541435 0.11261223366038964 LGFSLT(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 2 LGFSLTPSK 9 0 P38432 P38432 COIL Coilin 1 LGFS(0.001)LT(0.961)PS(0.038)K;LGFS(0.001)LT(0.856)PS(0.143)K 127.51 0.0033249000000000004 185968000.0 236174.0 194311.0 254430.0 272560.0 297520.0 280580.0 261120.0 304190.0 258060.0 287750.0 True False 311272.41927562846 257118.23079129314 251056.0919583911 209725.5030100226 256214.48356902538 263035.28824507823 284359.17414353293 257184.42509080717 271700.5247600682 277675.9600842837 1.120991601797819 0.9259650374964018 0.9041333354251746 0.7552886571324505 0.9227103545127058 0.9472742550894159 1.0240683927309395 0.9262034243538523 0.9784805450122446 1.0 18.083042755056084 -6.933935154852952 4.04650465963011 0.9771923428796943 0.9155908834770302 0.07969543617092123 0.08577522053228201 0.5868708827825094 19.273379726121888 0.03350580603938416 0.028885424426869578 1.1642998597550903e-07 6.933935154852952 -0.06160145940266404 LGFSLT(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGFSLTPSK 9 0 P38432 P38432 COIL Coilin 1 LGFSLT(0.99)PS(0.01)K;LGFS(0.002)LT(0.949)PS(0.048)K 113.67 0.0050996 169809000.0 203087.0 240161.0 256600.0 269540.0 285910.0 216417.0 270460.0 230651.0 227343.0 197417.0 True False 237465.6179489115 264002.5969112445 262718.3171609187 254438.54766047103 229887.98792210862 205067.71153964545 244840.0708391677 224596.6556449349 230667.4612843 233207.1393478878 1.018260498426127 1.1320519502510489 1.126544915801259 1.0910409877328462 0.9857673678642066 0.879337194020183 1.0498823986427208 0.9630779583891376 0.9891097756668623 1.0 17.83125242997407 -6.268710146630549 5.142730059416118 0.974035889105961 1.0980627244372576 0.5636509381467332 0.04911328444164683 0.12689927934234832 10.958239002677495 0.01500802918205415 0.01810566781391667 5.386291501638356e-07 6.268710146630549 0.12402683533129666 LGFSLT(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 2 LGFSLTPSK 9 0 P38432 P38432 COIL Coilin 1 LGFS(0.001)LT(0.999)PSK;LGFS(0.011)LT(0.983)PS(0.005)K 152.64 0.00022638 136890000.0 616780.0 702620.0 730660.0 754210.0 796180.0 674170.0 657080.0 665720.0 727330.0 606160.0 True False 607984.6040964007 700993.1265588445 670587.9552291624 809677.1193708044 749350.2577501069 645337.3206670283 691100.3872828683 696651.7815303439 645410.4362755555 710933.9483425712 0.855191407744446 0.9860172357686644 0.943249308592635 1.1388921871834046 1.054036397469972 0.9077317550688486 0.9721021044135792 0.9799106979691661 0.907834599515506 1.0 19.439356002178542 -10.256995542209019 18.115578783407116 0.9999535979262304 0.9769659159589414 0.008057183395722145 0.07603458541402124 0.0 0.0 0.07653881414458914 0.018563389128097654 5.5335578907557565e-11 10.256995542209019 -0.022987681967288953 LGFVDVQNCIS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 LGFVDVQNCISR 12 0 Q14573 Q14573 ITPR3 Inositol 1,4,5-trisphosphate receptor type 3 1 LGFVDVQNCIS(1)R;LGFVDVQNCIS(1)R 83.87700000000001 0.010544 11129400.0 27485.0 26587.0 44397.0 34889.0 31885.0 22906.9 35378.0 28345.0 29355.0 27426.0 True False 36224.65827648536 35180.72781287789 43808.266771515555 26845.88007967665 27458.318125162517 21474.52792180904 38526.57346373275 23964.93155330198 30906.64537057972 26465.82408782471 1.3687334335887953 1.329288961346281 1.6552768818435937 1.0143602553463198 1.0375009685715546 0.8114059796720309 1.4557103280020836 0.9055048304476098 1.1677945590516472 1.0 14.691842956586957 -5.77844354535719 24.99814583419293 1.057789633148669 1.4389186949906538 0.5027303856763472 0.1799251480620756 190.18637075229998 279596.0587417145 0.04929314361534924 0.07332270277406686 1.6655453206462803e-06 5.77844354535719 0.3811290618419849 LGFVDVQNCIS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGFVDVQNCISR 12 0 Q14573 Q14573 ITPR3 Inositol 1,4,5-trisphosphate receptor type 3 1 LGFVDVQNCIS(1)R 75.911 0.019229 4280600.0 11972.0 18436.0 14355.0 13598.0 19545.0 13748.0 12946.0 14495.0 12918.0 11319.0 True False 13998.623142221677 20266.204240720614 14697.27764164067 12836.148145310808 15715.297554956453 13027.0306780292 11719.661159076624 14114.521608721998 13106.901311545023 13371.045098845298 1.0469356014235998 1.5156783999233367 1.099186902219775 0.9599958754472616 1.1753230535669648 0.9742716879441379 0.8764955224097416 1.0556034703630537 0.9802450903913946 1.0 13.706824612370063 -5.508988848803025 22.71305481704044 1.0079491940972836 1.2878385450764378 0.4282603407584742 0.1271906587126881 156.83431815038514 256456.66432559543 0.03188756446827736 0.062167570477193394 3.097498831371828e-06 5.508988848803025 0.27988935097915424 LGFVDVQNCIS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 2 LGFVDVQNCISR 12 0 Q14573 Q14573 ITPR3 Inositol 1,4,5-trisphosphate receptor type 3 1 LGFVDVQNCIS(1)R;LGFVDVQNCIS(1)R 73.415 0.022713 8664100.0 21668.2 34333.2 19073.3 13233.1 18310.9 17478.3 19440.0 18278.2 24665.6 10680.4 True False 21359.20749453877 34253.70358482553 17505.166899067146 14206.306318327515 17233.88886261451 16730.79385290731 20446.508079349478 19127.471899849705 21887.500387717188 12526.492909261557 1.7051227066712884 2.7345006964798424 1.397451547362037 1.1341008549826406 1.375795203609823 1.3356327245064157 1.6322611785643688 1.5269614598757857 1.7472967530708057 1.0 13.612694933823201 -5.287368919730091 24.314461310748673 1.4090445577595365 2.219811649466316 0.5323768381390039 0.30943415326724333 336.7857876891845 315807.9242536541 0.07742990455770093 0.16128699123184342 5.159778758082921e-06 5.287368919730091 0.8107670917067793 LGGAVPFAPPEVS(ph)PEQAK ddPTM_PC-9_AZD4547_30min_R2 3 LGGAVPFAPPEVSPEQAK 18 0 A0A096LNZ0;A0A096LP25;Q6ZSR9 A0A096LNZ0;A0A096LP25 AAK1 Uncharacterized protein FLJ45252 1 LGGAVPFAPPEVS(1)PEQAK;LGGAVPFAPPEVS(1)PEQAK;LGGAVPFAPPEVS(1)PEQAK 216.53 1.5774e-27 39452900.0 234513.0 224544.0 290214.0 360679.0 326435.0 296381.0 275628.0 320810.0 255206.0 286410.0 True False 309083.2558265752 297123.45680275495 286365.5727375412 277530.0289850007 281115.1349282561 277848.24921720935 300158.35803781234 271236.185980413 268695.6681466246 276382.8730764198 1.1183155178400428 1.0750429413207538 1.036119096491052 1.0041506041811197 1.0171221240996646 1.005301978825527 1.0860237275079583 0.9813784152443348 0.9721863918547886 1.0 18.076308691851544 -5.034946010002313 1.4285831465315038 1.0115559593518244 1.1354967320991454 0.6021896609247981 0.028939899675178418 0.5663585446352787 1.4777061450189835 0.00894820063499583 0.0882259918390046 9.22686125193773e-06 5.034946010002313 0.12394077274732096 LGGAVPFAPPEVS(ph)PEQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LGGAVPFAPPEVSPEQAK 18 0 A0A096LNZ0;A0A096LP25;Q6ZSR9 A0A096LNZ0;A0A096LP25 AAK1 Uncharacterized protein FLJ45252 1 LGGAVPFAPPEVS(1)PEQAK;LGGAVPFAPPEVS(1)PEQAK;LGGAVPFAPPEVS(1)PEQAK;LGGAVPFAPPEVS(1)PEQAK 212.72 1.1434e-67 22231300.0 272512.0 256984.0 267720.0 313012.0 340191.0 291870.0 316739.0 314897.0 280106.0 241563.0 True False 318642.8992426591 282495.6731719113 274103.46013375424 295474.95243859594 273533.0156315263 276563.8233922299 286735.1889282222 306631.28741095087 284202.02034151024 285356.45968834433 1.116648628142741 0.9899746915855435 0.9605651136586142 1.0354591333285486 0.9585660542966816 0.9691871832664402 1.004831603396621 1.0745552693842715 0.9959543956071822 1.0 18.12240569648344 -4.75874409216319 24.9980836743905 0.9990763914703699 1.1166487848772066 0.5282329643559338 0.033413920645464106 62.783772271299846 582190.1157894549 0.008750592417463952 0.05854406890422445 1.7428335347933535e-05 4.75874409216319 0.11757239340683678 LGGAVPFAPPEVS(ph)PEQAK ddPTM_PC-9_Lapatinib_30min_R1 7 LGGAVPFAPPEVSPEQAK 18 0 A0A096LNZ0;A0A096LP25;Q6ZSR9 A0A096LNZ0;A0A096LP25 AAK1 Uncharacterized protein FLJ45252 1 LGGAVPFAPPEVS(1)PEQAK;LGGAVPFAPPEVS(1)PEQAK;LGGAVPFAPPEVS(1)PEQAK;LGGAVPFAPPEVS(1)PEQAK;LGGAVPFAPPEVS(1)PEQAK;LGGAVPFAPPEVS(1)PEQAK;LGGAVPFAPPEVS(1)PEQAK 158.14 1.0479e-05 28522600.0 442695.0 347432.2 384904.89999999997 358078.80000000005 392004.7 374225.9 312990.89999999997 328572.2 385141.4 276645.6 True False 436382.0881196794 346627.7420870714 353259.50489788025 384413.1094678603 368947.75425689336 358221.1306201808 329196.0373257645 343838.86392378854 341762.71981326013 324463.4233529088 1.3449346111504228 1.0683106850846948 1.088749854289896 1.1847656216391025 1.1371012191275573 1.1040416417925627 1.014585970658727 1.0597153305314346 1.0533166305205854 1.0 18.307696327325104 LGGGMGSMNS(ph)VTGGMGMGLDR ddPTM_PC-9_Lapatinib_30min_R1 1 LGGGMGSMNSVTGGMGMGLDR 21 0 A0A0A0MQW0;Q9P2K5-2;A0A0C4DGV1;H0YN19;Q9P2K5-3 A0A0A0MQW0 MYEF2 Myelin expression factor 2 1 LGGGMGS(0.192)MNS(0.794)VT(0.014)GGMGMGLDR 47.68 0.03379 4934600.0 9605.9 9036.3 12838.0 11400.0 12085.0 8658.4 9320.6 10232.0 10428.0 8827.0 True False 9468.91810449368 9015.37700253862 11782.509196113095 12238.394029285182 11374.184060024161 8288.100415716212 9803.175061953943 10707.416073752456 9253.488828291831 10352.735188761819 0.9146296057849961 0.8708207867931426 1.1381059189945606 1.1821411256196621 1.0986646381500373 0.8005710823853752 0.9469164315721668 1.0342596307665295 0.89382068212628 1.0 13.337724357123816 -6.7249427949560685 24.998521367330333 0.9379920005127579 1.0446752172637834 0.19955274239049958 0.10569109143437024 324.2214094136001 222076.24187366638 0.038554453075523076 0.038553375050852996 1.883897219112403e-07 6.7249427949560685 0.10668321675102554 LGGHGPSFPLK ddPTM_PC-9_Lapatinib_30min_R1 1 LGGHGPSFPLK 11 0 P13010 P13010 XRCC5 X-ray repair cross-complementing protein 5 0 71.221 0.025404 2547400.0 48383.0 47175.0 54153.0 55055.0 59902.0 57986.0 45993.0 49030.0 51224.0 49707.0 False True 47693.04954764449 47065.769185923346 49700.74937662507 59103.928358096084 56378.68213186322 55506.073951968036 48374.29249452262 51308.112792814994 45454.61370736677 58298.78871958585 0.8180795964225875 0.8073198469406844 0.8525177017945107 1.0138105723325217 0.9670643828131963 0.9520965215752487 0.829764966939544 0.880088830654859 0.77968367277751 1.0 15.831178288251369 -5.532413406141632 24.96622632291843 0.9139565378339602 0.8170044615560543 0.27842768808734053 0.06928838236706042 269.78888737663226 706432.0681555226 0.02004985955658318 0.03478348856150156 2.9348546254842183e-06 5.532413406141632 -0.09695207627790592 LGGLRPES(ph)PESLTSVSR ddPTM_PC-9_AZD4547_30min_R2 4 LGGLRPESPESLTSVSR 17 1 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 LGGLRPES(0.992)PES(0.008)LTSVSR;LGGLRPES(0.852)PES(0.142)LT(0.002)S(0.002)VS(0.002)R;LGGLRPES(0.955)PES(0.044)LT(0.001)SVSR;LGGLRPES(0.998)PES(0.001)LTSVSR 210.2 5.2057e-17 1309850000.0 152839.0 152509.0 230489.0 296326.0 228402.0 267871.0 210012.0 302641.0 201646.0 202016.0 True False 201438.62275130991 201804.55177395674 227432.565261163 228012.61889106216 196692.32480549987 251120.98402415455 228702.66115284752 255874.7874483286 212304.59589153214 194943.4813288847 1.0333180744395727 1.0351951775884052 1.1666589911640426 1.16963448757944 1.0089710282421023 1.2881732813650437 1.173174191790535 1.312558828354194 1.089057169002527 1.0 17.572696388024752 -5.260203282984469 22.414512355313626 1.1634712845224315 1.034256571185056 0.179519584448675 0.0969806113654456 36.453377794821265 660915.8149286455 0.024378811388762238 0.057511208818733936 5.492837069519594e-06 5.260203282984469 -0.12921471333737555 LGGLRPES(ph)PESLTSVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LGGLRPESPESLTSVSR 17 1 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 LGGLRPES(0.996)PES(0.004)LTSVSR;LGGLRPES(0.962)PES(0.001)LTS(0.013)VS(0.024)R;LGGLRPES(0.914)PES(0.085)LTS(0.001)VSR;LGGLRPES(0.309)PES(0.274)LT(0.159)S(0.248)VS(0.01)R;LGGLRPES(0.969)PES(0.029)LT(0.001)SVS(0.002)R 166.36 0.00011565 742656700.0 132000.0 170202.0 176051.0 178939.0 184389.0 174108.0 165180.0 156643.0 164200.0 123725.0 True False 154344.9928811608 187098.52973416852 180248.72351713572 168913.6279580656 148259.2990975116 164977.4699803831 149532.95460036115 152531.2872269775 166601.11436411942 146155.36309343897 1.0560337274964458 1.2801345484294961 1.2332679396916857 1.1557128276577644 1.0143952021981402 1.1287814999639179 1.0231095967704096 1.0436242912924265 1.139890530446079 1.0 17.157143243480526 -6.075464421581923 4.916810289163315 1.0627916853727084 1.1985942583312899 0.439586943370339 0.06841557660301925 0.19315157862737029 8.516253012914236 0.019693504106821098 0.026160453826097736 8.404958596630815e-07 6.075464421581923 0.13580257295858145 LGGLRPES(ph)PESLTSVSR ddPTM_PC-9_Lapatinib_30min_R1 3 LGGLRPESPESLTSVSR 17 1 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 LGGLRPES(0.737)PES(0.056)LT(0.026)S(0.056)VS(0.125)R;LGGLRPES(0.972)PES(0.019)LT(0.005)S(0.002)VS(0.001)R;LGGLRPES(0.88)PES(0.085)LT(0.034)S(0.001)VSR 86.74799999999999 0.0014214 1283660000.0 429644.0 405156.0 506116.0 400353.0 500550.0 462862.0 403295.0 376532.0 505535.0 346697.0 True False 423517.19777293963 404217.8861747108 464505.0961442583 429796.29515845707 471108.6331191642 443066.4712440217 424175.64176240936 394027.05131764675 448596.32478044805 406623.1145052864 1.0415472772328922 0.9940848706215291 1.1423479865609543 1.05698933441441 1.1585879314616274 1.0896244100217316 1.043166575216655 0.9690227566060416 1.103223866961493 1.0 18.633332702000963 -11.087044796511599 7.016768683291989 0.9999421327106229 1.0661649674172975 0.11025194305695463 0.056675270269791626 5.316818213874115e-05 3.302475379015479e-06 0.056861295864644334 0.013778849331417917 8.183803696628927e-12 11.087044796511599 0.06622283470667456 LGGLRPESPES(ph)LTSVSR ddPTM_PC-9_AZD4547_30min_R2 1 LGGLRPESPESLTSVSR 17 1 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 LGGLRPES(0.397)PES(0.595)LT(0.008)SVSR 94.538 0.008390799999999999 315830000.0 155580.0 139260.0 195200.0 199190.0 178510.0 186510.0 191170.0 210320.0 184380.0 175900.0 True False 205051.20373496768 184273.0716222732 192611.52045858587 153269.82295482213 153726.96780689197 174847.5002159435 208183.75965463812 177819.87667279833 194125.95038076947 169741.79453979313 1.208018356886741 1.0856081268722149 1.1347324386477564 0.902958657709316 0.9056518356229187 1.0300792488378778 1.2264731866366176 1.047590413161983 1.1436544011278253 1.0 17.37298230950845 -4.721126500173208 1.583708091087272 1.0453482174449076 1.279352666149168 0.20386073339674404 0.09580031635650223 2.2529041027683627 4.8583266334067945 0.029486796027489423 0.8597267667848225 1.9005246193981612e-05 4.721126500173208 0.23400444870426051 LGGLRPESPES(ph)LTSVSR ddPTM_PC-9_Lapatinib_30min_R1 1 LGGLRPESPESLTSVSR 17 1 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 LGGLRPES(0.049)PES(0.871)LT(0.063)S(0.017)VSR 105.25 0.0035455 353420000.0 22859.0 22904.0 29481.0 22717.0 28954.0 24525.0 22389.0 23593.0 27939.0 25198.0 True False 22533.0264681728 22850.967195217567 27057.18597995095 24387.68396169048 27250.982645754215 23476.122920567326 23548.192869781644 24689.216910481005 24792.21560928707 29553.440725775523 0.7624501890407721 0.7732083518548728 0.9155342090625873 0.8252062488419617 0.9220917083264291 0.7943617509176262 0.7968003823407167 0.8354092215377107 0.8388943892974238 1.0 14.85103848386234 -9.054815453563386 2.29501678069531 0.9999982432098611 0.8302466225534494 0.5025681741852852 0.05100592836362009 7.753925307707013 32.365402433259426 0.05057909202238056 0.013736859657696934 8.814233400749645e-10 9.054815453563386 -0.1697516206564117 LGGLRPESPESLT(ph)SVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGGLRPESPESLTSVSR 17 1 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 LGGLRPES(0.164)PES(0.152)LT(0.26)S(0.26)VS(0.164)R 54.511 0.039883 341840000.0 29055.0 42659.0 51332.0 45130.0 50785.0 52450.0 38623.0 43328.0 45161.0 36967.0 True False 33973.437637591946 46893.90359649061 52555.949557694075 42601.51241343409 40834.043813172895 49699.42966705199 34964.349833695065 42190.68590981074 45821.39418878195 43668.82446938904 0.7779792117236093 1.0738531244266099 1.2035118919799348 0.975558946939295 0.9350845668354717 1.1380986383521792 0.8006707361267388 0.9661511712866362 1.049293053924587 1.0 15.414316074967841 -7.242730176255833 24.995313735562362 0.9512079666462372 1.0227394241672518 0.05786718838507843 0.12381522406238918 2500.6345798453535 3340828.5011115004 0.04801133124962759 0.03711688946567918 5.7183380217123766e-08 7.242730176255833 0.07153145752101464 LGGPEGPGS(ph)PLLAT ddPTM_PC-9_AZD4547_30min_R2 1 LGGPEGPGSPLLAT 14 0 Q9C086 Q9C086 INO80B INO80 complex subunit B 1 LGGPEGPGS(1)PLLAT 71.888 0.024056 4026800.0 23030.0 26483.0 33255.0 52575.0 45916.0 33881.0 34606.0 47189.0 34385.0 37066.0 True False 30353.060946241887 35043.11184670874 32814.01697156902 40454.64602565282 39541.35596785205 31762.41571399066 37685.86695929489 39897.024345343685 36202.52090163122 35768.33062201236 0.8486015538998111 0.9797245562571123 0.9174042064846825 1.1310185664845211 1.105485083598442 0.888003861562485 1.0536098918774377 1.1154287508400087 1.012138958460411 1.0 15.126395166052962 -5.7335599709172795 24.869438266389796 1.0449826226973582 0.921691418726092 0.39621327125927774 0.07250700442230652 224.45349895147837 200218.82026665294 0.020189227572945723 0.03495884738509926 1.8468857442827953e-06 5.7335599709172795 -0.12329120397126625 LGGPEGPGS(ph)PLLAT ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGGPEGPGSPLLAT 14 0 Q9C086 Q9C086 INO80B INO80 complex subunit B 1 LGGPEGPGS(0.989)PLLAT(0.011) 79.283 0.012956 2802000.0 22510.0 20321.0 27505.0 29439.0 34775.0 31182.0 32340.0 28067.0 24158.0 25189.0 True False 26320.498407234358 22338.334583189626 28160.82351329338 27789.628272525744 27961.088384426257 29546.761027226243 29276.521078675883 27330.270989444656 24511.265047554156 29755.566303985717 0.884557132549306 0.7507279261627575 0.9464052280369901 0.9339304111581759 0.9396926981248852 0.9929826482001284 0.9839006517161911 0.9184927186475292 0.823753942275698 1.0 14.860871954793156 -5.280915960854269 24.74466069856325 0.9423740808878441 0.8176425331354887 0.4430912260103076 0.05594403733582126 555.8056154013743 706140.8788335776 0.01466862019692588 0.030608362763539017 5.237017668879929e-06 5.280915960854269 -0.1247315477523554 LGGPEGPGS(ph)PLLAT ddPTM_PC-9_Lapatinib_30min_R1 1 LGGPEGPGSPLLAT 14 0 Q9C086 Q9C086 INO80B INO80 complex subunit B 1 LGGPEGPGS(0.999)PLLAT(0.001) 70.089 0.028204000000000003 3731900.0 47763.0 44105.0 48904.0 37914.0 42236.0 40937.0 41944.0 40574.0 40508.0 32229.0 True False 47081.890861338565 44002.87758230311 44883.30189489913 40702.32203739634 39751.76151917091 39186.219938807924 44115.65508643182 42459.2161626693 35945.5624718494 37799.73970755691 1.245561245278257 1.164105306616862 1.1873971154866465 1.0767884210922 1.0516411442702012 1.0366796237746005 1.1670888590169903 1.1232674217113952 0.9509473543984002 1.0 15.20608867950083 -1.5228787452803376 0.27513054927020947 1.029082639770265 2.594989722674995 0.5713747020664592 0.05747922889783118 43.26830307636501 0.6073217449547507 0.06920937043091917 32.37722716382054 0.029999999999999995 1.5228787452803376 1.56590708290473 LGGS(ph)AESLIPGFQSTQGDAFATTSFSAGTDLQR ddPTM_PC-9_AZD4547_30min_R2 2 LGGSAESLIPGFQSTQGDAFATTSFSAGTDLQR 33 0 A0A096LNZ0 A0A096LNZ0 AAK1 1 LGGS(0.923)AES(0.077)LIPGFQSTQGDAFATTSFSAGTDLQR;LGGS(0.668)AES(0.186)LIPGFQS(0.029)T(0.116)QGDAFATTSFSAGTDLQR 98.83200000000001 5.4477999999999995e-16 13435180.0 14941.6 14701.7 27022.2 31395.3 31351.1 26550.5 22569.0 33299.0 22274.7 25684.3 True False 19692.717995413273 19453.73701758706 26663.86797200817 24157.598637549723 26998.5409243777 24890.29303781791 24577.597278053694 28153.40468489689 23452.09516729868 24785.10047469249 0.7945385581761537 0.7848964355601801 1.0758022949809725 0.9746822960115294 1.0893052845174183 1.0042441854626667 0.9916279057714262 1.1359003653684479 0.9462174741331023 1.0 14.597185486816304 -5.25550985128852 24.99187045799584 1.0303249819856266 0.7897174633720081 0.7503242074407542 0.054778619914052626 201.95580400136214 851200.3853000514 0.013025636791024501 0.03256969837117749 5.552520219562897e-06 5.25550985128852 -0.2406075186136185 LGGS(ph)AESLIPGFQSTQGDAFATTSFSAGTDLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGGSAESLIPGFQSTQGDAFATTSFSAGTDLQR 33 0 A0A096LNZ0 A0A096LNZ0 AAK1 1 LGGS(0.99)AES(0.01)LIPGFQSTQGDAFATTSFSAGTDLQR 83.178 3.7478e-09 2008300.0 5913.7 5788.9 6036.0 8835.0 9026.5 6870.8 8143.2 7239.8 7034.0 7518.6 True False 6914.772609100927 6363.583734492711 6179.921131657471 8340.003593456471 7257.8221222724205 6510.483152647877 7371.817144337461 7049.762921202174 7136.858942979384 8881.662662795154 0.778544836888094 0.7164856374414499 0.6958067837393617 0.9390137759219718 0.8171693068996055 0.733025267883678 0.8300041809984114 0.7937436028428869 0.8035498773079205 1.0 13.116614061556541 -14.522878743289562 0.2120107256370663 2.013650776960848 0.7609411297977665 0.5011263366238206 0.06403553891288767 132.58468996088195 1.3193833717058308 57.22930262853399 0.14092628725894424 3.0000000137517915e-15 14.522878743289562 -1.2527096471630812 LGGS(ph)AESLIPGFQSTQGDAFATTSFSAGTDLQR ddPTM_PC-9_Lapatinib_30min_R1 1 LGGSAESLIPGFQSTQGDAFATTSFSAGTDLQR 33 0 A0A096LNZ0 A0A096LNZ0 AAK1 1 LGGS(0.95)AES(0.047)LIPGFQS(0.002)T(0.002)QGDAFATTSFSAGTDLQR 60.34 0.00030268 8817200.0 13086.0 12299.0 19418.0 11453.0 16335.0 8918.8 10009.0 13878.0 15095.0 9794.6 True False 12899.391240321504 12270.522421148302 17821.526995647622 12295.291826087992 15374.207415845636 8537.36371473825 10527.217045586875 14522.82254412985 13394.8421426031 11487.583559515862 1.1228985777114244 1.0681552266911594 1.5513730022781833 1.070311416007334 1.338332586326238 0.7431818598321519 0.9163996058045246 1.264219099594685 1.1660278311105159 1.0 13.487787735119099 -6.714441136284169 24.99999848266902 1.0281282471005695 1.2301695207574417 0.243968185211481 0.18638832084668605 199.77349779950046 106265.69385926251 0.06389298781868699 0.06389281438747924 1.9300069091182293e-07 6.714441136284169 0.2020412736568722 LGGS(ph)AVISLEGKPL ddPTM_PC-9_AZD4547_30min_R2 2 LGGSAVISLEGKPL 14 1 P23528;G3V1A4;E9PK25 P23528 CFL1 Cofilin-1 1 LGGS(0.998)AVIS(0.002)LEGKPL;LGGS(0.58)AVIS(0.42)LEGKPL 115.1 0.00079109 52676000.0 97717.0 106258.0 138260.0 184847.0 151358.0 123285.0 111814.0 137941.0 106447.0 113333.0 True False 128788.97336013554 140603.8205115575 136426.58206252076 142233.3800076814 130344.55432925654 115575.96946073999 121765.22938757992 116625.38801884043 112073.57110414241 109365.24616588066 1.1776042012907262 1.2856352949482277 1.2474399943798837 1.3005354533920925 1.1918279243074654 1.0567888201471165 1.1133813862851045 1.066384359817084 1.0247640364120232 1.0 16.738794829113452 -6.64554304380752 3.296428342440335 1.0589872407515648 1.2546487401517947 0.8419189797487739 0.04134630740338201 0.09338262563471168 2.003734579402433 0.014256444824032117 0.014136866176117788 2.2618143556488974e-07 6.64554304380752 0.19566149940022992 LGGS(ph)AVISLEGKPL ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGGSAVISLEGKPL 14 1 P23528;G3V1A4;E9PK25 P23528 CFL1 Cofilin-1 1 LGGS(0.939)AVIS(0.061)LEGKPL 118.16 0.00057726 22603000.0 56954.0 57790.0 66714.0 64931.0 70241.0 65754.0 61275.0 55921.0 52510.0 38499.0 True False 66595.18730722464 63527.00927919532 68304.71477425403 61293.12657914225 56477.78027923748 62305.744486698575 55470.588407416995 54453.133003197145 53277.85941083985 45478.56394208368 1.4643203640298028 1.396856095986146 1.501910105632164 1.3477366316403085 1.2418549616289807 1.3700024601929839 1.2197084428184235 1.197336245545098 1.1714938817920562 1.0 15.472899079110656 -7.337805567915444 0.23993473378100338 0.945104812093032 1.5747059429438908 0.8738352181496473 0.051524620132573196 0.8928591706869429 0.1697181805412878 0.1310422408672785 0.20774754386555777 4.5940364016893215e-08 7.337805567915444 0.6296011308508588 LGGS(ph)AVISLEGKPL ddPTM_PC-9_Lapatinib_30min_R1 2 LGGSAVISLEGKPL 14 1 P23528;G3V1A4;E9PK25 P23528 CFL1 Cofilin-1 1 LGGS(0.803)AVIS(0.197)LEGKPL;LGGS(0.999)AVIS(0.001)LEGKPL 111.07 0.0020962 37919000.0 168925.0 145153.0 155571.0 135523.0 140674.0 153643.0 134545.0 126524.0 151711.0 95573.0 True False 166516.09852294865 144816.90714667385 142780.55290142636 145489.8135114749 132399.83189572525 147072.04704932607 141511.0817662589 132402.76693857086 134623.70959234593 112092.66570698221 1.4855217999564125 1.2919391847209256 1.2737724810173072 1.2979423104433532 1.1811640936600378 1.3120577169052463 1.2624472874628427 1.1811902777357497 1.2010037297557128 1.0 16.77433235923204 -6.115507729074844 0.033669834394821595 5.956421231649779e-14 2.581576043878403 0.753110949282451 0.05846648186031774 165.73458569481966 1.4861887612052174 49.03235553921097 65.01183973549253 7.66464899378435e-07 6.115507729074844 2.5815760438783433 LGGSAVISLEGKPL ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGGSAVISLEGKPL 14 1 P23528;G3V1A4;E9PK25 P23528 CFL1 Cofilin-1 0 106.67 0.0075983000000000005 3238700.0 21293.0 22522.0 18098.0 24271.0 25828.0 22943.0 26620.0 19189.0 21680.0 19396.0 False True 24897.484344080032 24757.835317287365 18529.52495704721 22911.17455764369 20767.188807849358 21739.828691156814 24098.36088788969 18685.309082426116 21997.0289854696 22912.341261348476 1.0866407784384895 1.0805458523373213 0.8087137296748119 0.9999490796819288 0.9063756763645171 0.9488261563138635 1.0517633537757203 0.8155128657212753 0.9600515606223557 1.0 14.483837265235127 -5.14761749441245 10.678923026660987 0.93560152220167 1.0848916723503093 0.3912941322322592 0.07344181966171649 0.4320613331939023 38.133075162186195 0.01775618756016134 0.0470985545687639 7.118401920723722e-06 5.14761749441245 0.14929015014863922 LGGSAVISLEGKPL ddPTM_PC-9_Lapatinib_30min_R1 1 LGGSAVISLEGKPL 14 1 P23528;G3V1A4;E9PK25 P23528 CFL1 Cofilin-1 0 160.15 0.0042085000000000004 11115000.0 64319.0 59389.0 53439.0 58410.0 60170.0 59965.0 53099.0 51395.0 50253.0 53236.0 False True 63401.799265339956 59251.48841934929 49045.45170050541 62705.666250047994 56630.91889877147 57400.436735242394 55848.20640459762 53782.99932667194 44592.97795245008 62437.77166748888 1.015439814267956 0.9489686585051741 0.7855093221727385 1.004290585256402 0.9069977577092007 0.919322314078204 0.8944618764105827 0.861385630689901 0.7141987415875297 1.0 15.930131429651484 -7.637091219054297 2.615684486285452 0.8394576968289396 0.9261259988297706 0.10942793650502292 0.08747418891046652 0.5415586382142511 7.439443818507848 0.04919858890925014 0.024464008425972645 2.3062627312628002e-08 7.637091219054297 0.08666830200083109 LGGTCVNVGCVPK ddPTM_PC-9_Lapatinib_30min_R1 2 LGGTCVNVGCVPK 13 0 P00390-5;P00390-4;P00390-2;P00390-3;P00390;A0A2R8YF59;H0YC68 P00390-5 GSR Glutathione reductase, mitochondrial 0 ; 136.5 0.00011956 5402200.0 39255.0 36148.0 39867.0 36919.0 41923.0 38804.0 31832.0 31781.0 40953.0 37208.0 False True 38695.216501514646 36064.301526926494 36589.289151070334 39634.14641817362 39457.171563789205 37144.44337654205 33480.1052048278 33257.6612822446 36340.441885791624 43639.35322345646 0.8867046288100277 0.8264169577000439 0.8384470998851407 0.9082202986654254 0.9041649027598487 0.8511685126574389 0.7671998490305765 0.7621025250293666 0.8327447407322797 1.0 15.413342099262605 -7.008579001116696 24.37129604143959 0.8190437287211891 0.8710139749102338 0.011158559488825937 0.06681464274358799 653.6714145279499 1856958.2203756876 0.023546768701437615 0.01976810308643235 9.8043994941202e-08 7.008579001116696 0.051970246189044667 LGHDPYRLT(ph)PDPYR ddPTM_PC-9_AZD4547_30min_R2 2 LGHDPYRLTPDPYR 14 1 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6 P18583-10 SON Protein SON 1 LGHDPYRLT(1)PDPYR;LGHDPY(0.001)RLT(0.985)PDPY(0.014)R 88.507 0.003549 16027300.0 20932.0 21394.1 30321.0 47622.0 31038.0 23213.0 27306.0 36105.0 29191.0 33915.0 True False 27587.940587352816 28309.32444057211 29918.923728610545 36643.483652565614 26728.909454878285 21761.487440419856 29736.18110126874 30525.801860362248 30733.976665392358 32727.64617292259 0.8429552324535292 0.864997265339357 0.9141789046034158 1.1196492243576874 0.8167073584715239 0.6649267510849696 0.9085951658164511 0.93272219147914 0.9390830157171614 1.0 14.998222224621813 -8.190290862161596 1.7423678553736364 0.9861762170357152 0.8776866785674604 0.12037579893376171 0.10602385278664832 0.9093386708955427 4.998959698468133 0.10723062359833757 0.03261949473296684 6.4522195664882955e-09 8.190290862161596 -0.10848953846825482 LGHDPYRLT(ph)PDPYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGHDPYRLTPDPYR 14 1 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6 P18583-10 SON Protein SON 1 LGHDPY(0.004)RLT(0.983)PDPY(0.014)R;LGHDPY(0.013)RLT(0.985)PDPY(0.003)R 71.98 0.014874 9112400.0 21328.2 20352.4 26389.9 29822.8 38303.0 37055.0 34723.0 35316.0 28668.1 21948.1 True False 24938.643008848332 22372.85176767426 27019.135300253063 28151.925202822124 30797.80211038617 35111.77056840063 31433.78606724993 34388.99242039504 29087.31672778325 25927.116788936 0.9618749054075506 0.8629132174550751 1.0421187793539413 1.0858100972814504 1.1878606619124212 1.354248945389255 1.2123903449481825 1.3263716401767442 1.1218878275040522 1.0 14.66217416053518 -5.821910561090536 1.5402796404742962 1.225461465273423 0.914246856161628 0.5530608694046191 0.09986486048757245 0.2580975784821364 1.244403846655936 0.03156347227392303 0.06606453463947919 1.5069173698510544e-06 5.821910561090536 -0.311214609111795 LGHDPYRLT(ph)PDPYR ddPTM_PC-9_Lapatinib_30min_R1 1 LGHDPYRLTPDPYR 14 1 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6 P18583-10 SON Protein SON 1 LGHDPYRLT(0.993)PDPY(0.006)R 77.222 0.009594799999999999 6846900.0 28181.0 29280.0 30658.0 22820.0 24165.0 25724.0 19601.0 21257.0 26297.0 19137.0 True False 27779.13377223752 29212.20395895783 28137.417583302355 24498.25892528841 22743.66221021795 24623.844485572827 20615.843871570407 22244.677822493733 23335.1549403136 22444.804951550355 1.237664298362223 1.3015129345973677 1.2536271820601759 1.0914890540671067 1.0133152085443697 1.0970843604444849 0.9185129439116104 0.9910835879621757 1.0396684217432572 1.0 14.454093938638563 -5.8767195299461426 2.275515828751687 1.0084453634336734 1.2761365052642546 0.8676422779422971 0.04439102136367766 0.1002563604723385 1.0562177113986468 0.013943628006705216 0.023771128378625845 1.3282519741188679e-06 5.8767195299461426 0.2676911418305812 LGHPEALSAGTGS(ph)PQPPSFTYAQQR ddPTM_PC-9_AZD4547_30min_R2 4 LGHPEALSAGTGSPQPPSFTYAQQR 25 0 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 LGHPEALSAGT(0.002)GS(0.998)PQPPSFTYAQQR;LGHPEALSAGT(0.144)GS(0.856)PQPPSFTYAQQR;LGHPEALSAGTGS(1)PQPPSFTYAQQR;LGHPEALSAGTGS(1)PQPPSFTYAQQR 192.78 2.0375e-22 365570000.0 80606.3 57634.9 125407.0 172059.0 144967.0 114936.0 81046.0 138652.0 87708.0 121819.0 True False 106237.42668480509 76264.25431310176 123744.02124052196 132393.45583505087 124840.83436256649 107749.03375057483 88258.936993094 117226.5193059951 92344.06582056907 117554.15388881792 0.9037317965410552 0.6487584810080984 1.0526554540774322 1.1262337523203807 1.061985733661443 0.9165906111023799 0.7507938603051733 0.9972129050996131 0.785544897953224 1.0 16.842965993341963 -10.32279601188921 17.970700945482232 0.9999999999999997 0.9201398046801235 0.029106873375635334 0.1438120728948626 0.0 0.0 0.14795892504591454 0.03588531036571483 4.755585433323566e-11 10.32279601188921 -0.0798601953198762 LGHPEALSAGTGS(ph)PQPPSFTYAQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LGHPEALSAGTGSPQPPSFTYAQQR 25 0 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 LGHPEALSAGT(0.021)GS(0.979)PQPPSFTYAQQR;LGHPEALSAGT(0.002)GS(0.998)PQPPSFTYAQQR;LGHPEALSAGT(0.006)GS(0.994)PQPPSFTYAQQR;LGHPEALSAGTGS(1)PQPPSFTYAQQR;LGHPEALSAGTGS(1)PQPPSFTYAQQR;LGHPEALSAGTGS(1)PQPPSFTYAQQR 210.96 1.6644999999999998e-31 355078300.0 72985.2 75709.2 125547.0 123804.0 131444.0 119735.0 124025.0 114732.2 105827.3 80452.3 True False 85340.15283659173 83225.10903132797 128540.51661964877 116867.66325798353 105688.49177864892 113455.88581857902 112276.45413675881 111720.60131881414 107374.82405691834 95037.66512994375 0.8979613789954464 0.8757065834638864 1.352521828518167 1.2296983843004972 1.1120695319497005 1.1937991707124989 1.1813890206924242 1.1755402572870455 1.129813363050388 1.0 16.536211772224014 -5.239589525029278 24.861524539109162 1.1791782500246977 0.886833882230689 0.642367960520787 0.08492652454560008 432.01649014861476 491561.6105892599 0.020977069175394457 0.055393197371705075 5.759840735415803e-06 5.239589525029278 -0.29234436779400863 LGHPEALSAGTGS(ph)PQPPSFTYAQQR ddPTM_PC-9_Lapatinib_30min_R1 4 LGHPEALSAGTGSPQPPSFTYAQQR 25 0 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 LGHPEALSAGT(0.001)GS(0.999)PQPPSFTYAQQR;LGHPEALSAGTGS(1)PQPPSFTYAQQR;LGHPEALSAGT(0.002)GS(0.998)PQPPSFTYAQQR;LGHPEALSAGT(0.002)GS(0.998)PQPPSFTYAQQR 181.03 5.589400000000001e-46 262501000.0 79984.5 62005.8 88848.2 57931.6 66316.3 74488.6 53159.1 57037.1 67145.7 43731.9 True False 78843.90636263895 61862.229379724966 81543.4439599702 62192.08311815239 62415.70561686225 71302.89621940757 55911.41808852608 59687.25189017063 59583.04419043296 51290.90064590609 1.537190912418343 1.2061053442363885 1.5898228132689027 1.2125363823790918 1.216896268750627 1.3901665855247325 1.0900845449082357 1.1637006006626773 1.1616689011131398 1.0 15.646415284184512 -5.779503293497674 0.18120270502564 0.9340900331133623 1.7444696530645112 0.5331490090723487 0.12315632875593195 9.196019772694399 0.45683523878399707 0.4077068285182161 1.820447178119392 1.6614860777417653e-06 5.779503293497674 0.8103796199511489 LGHSLS(ph)VSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGHSLSVSK 9 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 LGHS(0.007)LS(0.934)VS(0.059)K;LGHS(0.007)LS(0.708)VS(0.285)K 88.155 0.0079714 4063300.0 59724.0 57973.0 55154.0 62261.0 66632.0 53164.0 43076.0 56157.0 44940.0 33070.0 True False 69834.09359723073 63728.17630979043 56469.08053270982 58772.71802288544 53575.93792181424 50375.98625012684 38995.52943676696 54682.93825325985 45597.16248187286 39065.32921802404 1.787623322140353 1.6313231600871139 1.4455037667174198 1.504472615471234 1.3714446798286617 1.2895318498143944 0.9982132550101518 1.399781835910655 1.1672028213916894 1.0 15.253601151917275 -1.5228787452815675 0.20341560758067606 1.0183700139992897 4.789829346315835 0.8074250362968323 0.10650181675847371 22.74666928353335 0.27774422385750214 0.19444004063123482 27.481650275452544 0.029999999999915036 1.5228787452815675 3.771459332316545 LGHVVMGNNAVS(ph)PYQQVIEK ddPTM_PC-9_AZD4547_30min_R2 4 LGHVVMGNNAVSPYQQVIEK 20 0 P60228;H0YAW4;E5RGA2 P60228 EIF3E Eukaryotic translation initiation factor 3 subunit E 1 LGHVVMGNNAVS(1)PYQQVIEK;LGHVVMGNNAVS(1)PYQQVIEK;LGHVVMGNNAVS(1)PYQQVIEK;LGHVVMGNNAVS(1)PYQQVIEK 171.9 6.2365e-09 69653000.0 270241.0 224107.0 316399.0 407664.0 328271.0 321532.0 302064.0 369790.0 263470.0 331403.0 True False 356172.01663800905 296545.205098756 312203.34252856555 313683.36314601474 282696.2380199218 301426.55321126385 328947.1108244944 312647.4524288417 277396.4863153342 319800.68184122257 1.1137312609447294 0.9272813409634547 0.9762435174655787 0.9808714645009887 0.8839763454922129 0.9425450611169076 1.0286004048853559 0.9776322258877097 0.8674042991973934 1.0 18.286813489202217 -4.755444805013844 24.997982662346704 0.9544854031445301 1.1137315207484795 0.5032572059130485 0.04765219040267638 170.26217949491144 709940.2764210718 0.01191910508097543 0.10607133758710593 1.7561240678485652e-05 4.755444805013844 0.15924611760394936 LGHVVMGNNAVS(ph)PYQQVIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LGHVVMGNNAVSPYQQVIEK 20 0 P60228;H0YAW4;E5RGA2 P60228 EIF3E Eukaryotic translation initiation factor 3 subunit E 1 LGHVVMGNNAVS(0.983)PY(0.017)QQVIEK;LGHVVMGNNAVS(0.996)PY(0.004)QQVIEK;LGHVVMGNNAVS(0.998)PY(0.002)QQVIEK 126.63 1.6179e-06 41238000.0 164457.0 169400.0 160065.0 186506.0 199480.0 188683.0 201764.0 182284.0 168005.0 138755.0 True False 192296.32192619026 186216.91247440147 163881.55664989274 176056.67348061033 160393.3259791615 178788.13132256214 182651.45327513793 177499.23814586282 170461.7552907663 163910.1831160246 1.1731810572749615 1.1360911746562259 0.9998253527292347 1.0741045500265702 0.9785439984874298 1.0907689072374847 1.114338656713276 1.082905495994835 1.039970501223247 1.0 17.32254596081212 -5.083522607013238 5.409659152318343 1.0531483237100718 1.1651642389059433 0.5089872264818407 0.04243567437580031 0.16693987188701154 7.982438425707664 0.011133853245020453 0.03187492556582567 8.250445370209944e-06 5.083522607013238 0.11201591519587151 LGHVVMGNNAVS(ph)PYQQVIEK ddPTM_PC-9_Lapatinib_30min_R1 4 LGHVVMGNNAVSPYQQVIEK 20 0 P60228;H0YAW4;E5RGA2 P60228 EIF3E Eukaryotic translation initiation factor 3 subunit E 1 LGHVVMGNNAVS(0.993)PY(0.007)QQVIEK;LGHVVMGNNAVS(1)PYQQVIEK;LGHVVMGNNAVS(0.999)PY(0.001)QQVIEK;LGHVVMGNNAVS(1)PYQQVIEK 122.47 4.759e-06 45219700.0 335380.0 286494.0 338770.0 298743.0 285962.0 300571.0 257766.0 239955.0 316958.0 217552.0 True False 330597.4196988413 285830.6407451383 310917.63829001604 320713.55679743306 269142.27738292346 287716.2789952227 271111.8622212754 251104.18529879473 281258.85232429235 255155.57333018203 1.2956699921699706 1.1202210361882294 1.2185414342789038 1.2569333783762435 1.0548163768096182 1.1276111873241574 1.0625355295314096 0.9841218908977363 1.1023033855518867 1.0 17.96101762910459 -6.561505257955896 1.190274605789568 1.037724164349651 1.217924398957 0.6239296572230097 0.06134125696619314 0.3156814382804973 0.9419088190922379 0.027872491700104425 0.030445455819883883 2.744699113504753e-07 6.561505257955896 0.18020023460734902 LGIAVIHGEAQDAES(ph)DLVDGRHSPPMVR ddPTM_PC-9_AZD4547_30min_R2 2 LGIAVIHGEAQDAESDLVDGRHSPPMVR 28 1 O60256;O60256-2;O60256-3;E7EPA1;C9K0K7;I3L0S1;O60256-4 O60256 PRPSAP2 Phosphoribosyl pyrophosphate synthase-associated protein 2 1 LGIAVIHGEAQDAES(0.866)DLVDGRHS(0.134)PPMVR;LGIAVIHGEAQDAES(0.806)DLVDGRHS(0.194)PPMVR 52.019 0.0049518 9329100.0 12428.400000000001 8836.4 15117.400000000001 22658.3 17830.9 15281.9 10768.6 14667.4 11533.7 13183.2 True False 16380.372673220698 11692.593494779932 14916.933398466314 17434.779002245345 15355.387318737978 14326.320377191745 11726.984538457576 12400.890353321613 12143.347835484781 12721.660180653784 1.287597093509134 0.9191090886519053 1.1725618501546637 1.370479855196804 1.207026999674884 1.1261360682293824 0.9218124342207442 0.9747855372037074 0.9545411261614691 1.0 13.634999334614053 -7.126836498702956 4.025093728521195 0.9612843616891269 1.1838943526178407 0.4921946880307898 0.1096182891244216 0.22662311486148873 6.266275943216616 0.04633030138805478 0.03544518740733068 7.467298310962181e-08 7.126836498702956 0.2226099909287138 LGIAVIHGEAQDAES(ph)DLVDGRHSPPMVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LGIAVIHGEAQDAESDLVDGRHSPPMVR 28 1 O60256;O60256-2;O60256-3;E7EPA1;C9K0K7;I3L0S1;O60256-4 O60256 PRPSAP2 Phosphoribosyl pyrophosphate synthase-associated protein 2 1 LGIAVIHGEAQDAES(0.5)DLVDGRHS(0.5)PPMVR;LGIAVIHGEAQDAES(0.587)DLVDGRHS(0.413)PPMVR;LGIAVIHGEAQDAES(0.748)DLVDGRHS(0.252)PPMVR 69.398 7.3449e-05 24228700.0 19111.0 16865.6 22286.800000000003 22338.4 27089.300000000003 22390.4 24108.199999999997 25491.0 25505.6 20581.5 True False 22346.114840544473 18539.90530713265 22818.201835159674 21086.851870069946 21781.346127167148 21216.208007953508 21824.49676774687 24821.888259947038 25878.571148145427 24312.763026935634 0.9191104612745022 0.7625585494578568 0.9385277111400229 0.8673161436529544 0.8958811511071786 0.8726366470338434 0.8976559654518879 1.0209406570716522 1.0644027221206847 1.0 14.569426237487992 -7.744693474112312 3.6944599584259286 1.036416948478543 0.874903907322353 0.6898384332291363 0.046100372159932845 0.11839529512670104 3.439076266751429 0.02461862481721323 0.012153537911614335 1.800141009874731e-08 7.744693474112312 -0.16151304115619003 LGIAVIHGEAQDAESDLVDGRHS(ph)PPMVR ddPTM_PC-9_AZD4547_30min_R2 6 LGIAVIHGEAQDAESDLVDGRHSPPMVR 28 1 O60256;O60256-2;O60256-3;E7EPA1;C9K0K7;I3L0S1;O60256-4 O60256 PRPSAP2 Phosphoribosyl pyrophosphate synthase-associated protein 2 1 LGIAVIHGEAQDAES(0.006)DLVDGRHS(0.994)PPMVR;LGIAVIHGEAQDAES(0.107)DLVDGRHS(0.893)PPMVR;LGIAVIHGEAQDAESDLVDGRHS(1)PPMVR;LGIAVIHGEAQDAES(0.099)DLVDGRHS(0.901)PPMVR;LGIAVIHGEAQDAES(0.015)DLVDGRHS(0.985)PPMVR;LGIAVIHGEAQDAES(0.073)DLVDGRHS(0.927)PPMVR 75.3 1.2024e-05 48876600.0 93603.1 82719.1 129251.59999999999 169292.4 149228.29999999996 124058.6 98234.40000000001 144514.49999999997 100810.90000000001 127705.6 True False 123366.9387345712 109456.43141483533 127537.63933250478 130264.65272150685 128510.52641295856 116301.19613044719 106977.07129475093 122183.10463784284 106139.55836446852 123234.66581455925 1.0010733418161006 0.888195141288758 1.034916908237659 1.057045530658769 1.0428114975889844 0.9437376679826001 0.868076126044985 0.9914670018394112 0.861280043751528 1.0 16.91104861654022 -6.91696458739042 6.968243806521226 0.9262419452253327 1.002580368427524 0.2646636305456386 0.06002395667880076 0.31313811213323234 21.864286440365824 0.02171306795833621 0.019132585203718345 1.2106968504090548e-07 6.91696458739042 0.07633842320219142 LGIAVIHGEAQDAESDLVDGRHS(ph)PPMVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 10 LGIAVIHGEAQDAESDLVDGRHSPPMVR 28 1 O60256;O60256-2;O60256-3;E7EPA1;C9K0K7;I3L0S1;O60256-4 O60256 PRPSAP2 Phosphoribosyl pyrophosphate synthase-associated protein 2 1 LGIAVIHGEAQDAES(0.015)DLVDGRHS(0.985)PPMVR;LGIAVIHGEAQDAES(0.031)DLVDGRHS(0.969)PPMVR;LGIAVIHGEAQDAES(0.017)DLVDGRHS(0.983)PPMVR;LGIAVIHGEAQDAES(0.012)DLVDGRHS(0.988)PPMVR;LGIAVIHGEAQDAES(0.12)DLVDGRHS(0.88)PPMVR;LGIAVIHGEAQDAES(0.111)DLVDGRHS(0.889)PPMVR;LGIAVIHGEAQDAES(0.095)DLVDGRHS(0.905)PPMVR;LGIAVIHGEAQDAES(0.001)DLVDGRHS(0.999)PPMVR;LGIAVIHGEAQDAES(0.119)DLVDGRHS(0.881)PPMVR;LGIAVIHGEAQDAES(0.198)DLVDGRHS(0.802)PPMVR 105.46 1.3326e-10 94091000.0 146584.90000000002 149643.0 185275.1 198533.5 206908.5 180961.3 186599.3 180529.70000000004 176382.30000000002 142377.4 True False 171398.82838625505 164498.568083866 189692.76104372926 187410.31164929134 166366.26473009522 171471.3708638378 168923.2634420581 175790.98666202847 178961.55745497203 168189.29556112213 1.0190828602642343 0.9780561095464315 1.127852759064518 1.1142820416961914 0.9891608391310232 1.0195141747384449 1.0043639393249568 1.0451972349104928 1.0640484393368252 1.0 17.359726362358536 -6.286411125307974 24.977891723215404 1.0217964664728514 1.0588378925772357 0.15589604129529455 0.044861302894551654 1733.2991912034745 1733718.3553543163 0.015208478663399408 0.017252451844484037 5.171170707756806e-07 6.286411125307974 0.03704142610438432 LGIAVIHGEAQDAESDLVDGRHS(ph)PPMVR ddPTM_PC-9_Lapatinib_30min_R1 10 LGIAVIHGEAQDAESDLVDGRHSPPMVR 28 1 O60256;O60256-2;O60256-3;E7EPA1;C9K0K7;I3L0S1;O60256-4 O60256 PRPSAP2 Phosphoribosyl pyrophosphate synthase-associated protein 2 1 LGIAVIHGEAQDAES(0.007)DLVDGRHS(0.993)PPMVR;LGIAVIHGEAQDAES(0.101)DLVDGRHS(0.899)PPMVR;LGIAVIHGEAQDAES(0.002)DLVDGRHS(0.998)PPMVR;LGIAVIHGEAQDAES(0.233)DLVDGRHS(0.767)PPMVR;LGIAVIHGEAQDAES(0.117)DLVDGRHS(0.883)PPMVR;LGIAVIHGEAQDAES(0.063)DLVDGRHS(0.937)PPMVR;LGIAVIHGEAQDAES(0.032)DLVDGRHS(0.968)PPMVR;LGIAVIHGEAQDAES(0.094)DLVDGRHS(0.906)PPMVR;LGIAVIHGEAQDAES(0.076)DLVDGRHS(0.924)PPMVR;LGIAVIHGEAQDAES(0.176)DLVDGRHS(0.824)PPMVR 89.462 9.7816e-08 74062300.0 148894.2 135118.0 151762.7 129096.20000000001 138531.6 142289.50000000003 126716.70000000001 121260.2 159828.5 117318.7 True False 146770.94140414774 134805.1425726254 139285.3566269634 138590.36520029893 130383.44365160476 136204.10977802513 133277.47069642518 126894.39157412422 141826.93126128128 137597.0809776583 1.0666719116518104 0.9797093195204756 1.012269705413149 1.0072187884770747 0.947574197978627 0.9898764480341021 0.9686068174517852 0.9222171769379913 1.0307408431455736 1.0 17.07009033907184 -1.5228787693080936 0.8199303416987493 0.9768307141485922 24.317552927965707 0.36123896802282307 0.03128937716638966 597.8075175309368 1.904236912594921 0.01072145367025848 25964.565556642858 0.02999999834022146 1.5228787693080936 23.340722213817116 LGIHEDS(ph)QNR ddPTM_PC-9_AZD4547_30min_R2 3 LGIHEDSQNR 10 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 LGIHEDS(1)QNR;LGIHEDS(1)QNR;LGIHEDS(1)QNR 138.89 0.00012007 13616000.0 51439.3 48759.0 75389.0 90168.0 89231.0 71205.0 62085.0 81226.0 62832.0 71612.0 True False 67795.92739609299 64519.39321578641 74389.29260170249 69381.16068171301 76842.81588917605 66752.54009370152 67610.44472541814 68674.38808779331 66153.17124592963 69104.88567699648 0.9810583829481797 0.9336444534089363 1.0764693678737258 1.0039979084258654 1.1119737068714284 0.9659597789613593 0.9783743083149937 0.9937703740482929 0.9572864580825229 1.0 16.076500091506027 -9.663578528098022 10.513774405335319 0.9999980980083412 1.0021115913872256 0.0 0.051655192128759186 0.0 0.0 0.0510523933491336 0.012382024130532849 2.1698088284099312e-10 9.663578528098022 0.0021134933788844457 LGIHEDS(ph)QNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGIHEDSQNR 10 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 LGIHEDS(1)QNR;LGIHEDS(1)QNR 114.76 0.0025061999999999997 0.0 45633.0 45466.0 43310.0 51652.0 53606.0 45384.0 50742.0 52222.0 40784.0 36189.0 True False 53357.765607166824 49979.56400567388 44342.674654089686 48758.10589804341 43102.28911389082 43003.98314603411 45935.35041973319 50851.22783378271 41380.388844252375 42749.779228033614 1.2481413137258242 1.169118645948451 1.0372609041454772 1.1405463789171986 1.0082458878670897 1.0059463211878716 1.0745166700091542 1.1895085483958823 0.9679673109777548 1.0 15.38362934908147 -5.0076899758861675 2.2788156434077735 1.0594791916082718 1.2594429933210025 0.4922073645222673 0.0649760956689761 0.3393186999636484 2.906321869829485 0.017318250641414495 0.11304664059690067 9.824490207709192e-06 5.0076899758861675 0.19996380171273076 LGIHEDS(ph)QNR ddPTM_PC-9_Lapatinib_30min_R1 2 LGIHEDSQNR 10 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 LGIHEDS(1)QNR;LGIHEDS(1)QNR 118.76 0.00084653 8675100.0 50211.0 52366.0 53632.0 48487.0 56359.0 54060.0 43364.0 42452.0 50802.0 46774.0 True False 49494.98193243031 52244.74974435746 49222.58398550693 52052.8957278904 53044.074426057225 51747.979820015054 45609.17573831844 44424.474898645356 45080.14379122377 54858.82357756269 0.9022246323319592 0.9523490723509721 0.8972591968895047 0.9488518406577731 0.9669196487792039 0.943293648046438 0.8313917937710322 0.8097963463586741 0.8217482776947771 1.0 15.743436064130568 -7.256714734433653 24.562067307752606 0.8498837982149585 0.936276088585862 0.2643665236755294 0.05418673720099872 330.15910118138817 1716408.8069154646 0.020171876993918147 0.01508797682239596 5.537136956589044e-08 7.256714734433653 0.08639229037090346 LGIHEDS(ph)TNR ddPTM_PC-9_AZD4547_30min_R2 1 LGIHEDSTNR 10 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 1 LGIHEDS(0.959)T(0.041)NR 87.667 0.02511 0.0 12137.0 9986.4 14608.0 18400.0 16549.0 15461.0 10736.0 14791.0 13723.0 15081.0 True False 15996.313534717214 13214.308505304241 14414.288375302358 14158.164277166174 14251.45700653331 14494.221225879091 11691.483201612145 12505.390813367061 14448.369763940233 14553.01878029914 1.0991749393171886 0.9080115063956936 0.9904672420828189 0.9728678627373523 0.9792784041360502 0.9959597692198648 0.8033716837800868 0.859298747713841 0.9928091196789649 1.0 13.829030826678288 LGIHEDSQNR ddPTM_PC-9_AZD4547_30min_R2 4 LGIHEDSQNR 10 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ;;; 180.09 9.8454e-05 446099000.0 288592.0 262618.0 511840.0 758350.0 584512.0 507800.0 414634.0 593198.0 388234.0 496745.0 False True 380358.25291349663 347504.1327251049 505052.66716968553 583524.1238907055 503362.5982115417 476047.18572546367 451535.62274750764 501532.8794339606 408755.2566445799 479354.10874741164 0.7934807399636177 0.7249424306243236 1.0536108024387778 1.2173132831081765 1.050085081208266 0.9931012940921917 0.94196673087335 1.0462680308394638 0.8527208783349914 1.0 18.87073227276133 -5.262243581501228 24.972676086239364 1.0254976019845685 0.7592115674577389 0.5760172576637816 0.08916118733507977 47.83167513920298 1485365.6795647356 0.024627666432621768 0.05664348670839383 5.467092456406522e-06 5.262243581501228 -0.26628603452682964 LGIHEDSQNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 LGIHEDSQNR 10 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ;;;;;;; 217.66 7.4596e-08 403371600.0 964948.0 994601.0 1426107.0 1401904.0 1619065.0 1458468.0 1540641.0 1402711.0 1391808.0 977979.0 False True 1128294.6378082628 1093338.4141909825 1460110.7994209155 1323359.8639140893 1301820.8358053518 1381983.3705938242 1394700.3312050833 1365891.322545156 1412160.5589579535 1155278.8510224966 0.976642683980278 0.9463848604372072 1.2638600612558804 1.1454895610205538 1.1268455530482153 1.196233592756138 1.207241290681192 1.182304446529298 1.2223547221591566 1.0 20.139809688006153 -5.248817096883538 24.941836723889285 1.1746822185684174 0.9615137337669658 0.5965294781174668 0.06776446067491791 449.2267869116403 887675.3389215287 0.016076140742774386 0.04190454057486541 5.638750818112123e-06 5.248817096883538 -0.21316848480145156 LGIHEDSQNR ddPTM_PC-9_Lapatinib_30min_R1 4 LGIHEDSQNR 10 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ;;; 205.59 5.5419e-05 433597000.0 1047811.0 818867.0 1197740.0 879725.0 1003075.0 1082162.0 869795.0 888607.0 1104498.0 785119.0 False True 1032869.0229949967 816970.96377254 1099266.4406101052 944422.9111765717 944076.1006213274 1035880.453902833 914828.72916038 929894.9252393438 980097.8043604408 920825.7730446918 1.1216769265480442 0.8872155707276111 1.1937833114459893 1.0256260617617776 1.0252494318222207 1.1249472856061742 0.9934873196864563 1.0098489339244545 1.064368345294862 1.0 19.812568688145234 LGIHEDSQNRK ddPTM_PC-9_AZD4547_30min_R2 1 LGIHEDSQNRK 11 1 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 62.823 0.021204 16066000.0 47555.0 50587.0 76261.0 120120.0 105450.0 79661.0 67758.0 100430.0 69979.0 68724.0 False True 62676.50079455198 66938.2584672981 75249.72931194775 92428.18983550007 90810.08769949479 74679.78507695197 73788.33073536104 84910.85115181231 73677.94707503993 66317.99367795758 0.945090424461741 1.00935288833303 1.134680425909188 1.3937120939504668 1.369312952084643 1.126086314365895 1.1126441956866138 1.280359167138594 1.1109797354971644 1.0 16.017112741108015 -5.306252055589411 3.246660785599137 1.2135090285132795 0.9667952233174024 0.3505235679330232 0.11746536835469493 0.25344666336428434 5.363596656661674 0.032474031452834166 0.08546440352613312 4.940238824615358e-06 5.306252055589411 -0.24671380519587705 LGIHEDSQNRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGIHEDSQNRK 11 1 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ; 64.711 0.018453 14879200.0 95900.0 104444.0 128492.0 164295.0 165348.0 165798.0 157777.0 146372.0 147634.0 115270.0 False True 112133.97588866152 114812.51007365073 131555.7365886238 155090.08380157672 132949.24636054973 157103.261009302 142831.22035343957 142529.89009395376 149792.86795391256 136167.5385231824 0.8235000581256069 0.8431709298622888 0.966131414398936 1.1389651710210857 0.9763652027675837 1.1537497314938634 1.0489373745205999 1.0467244369676858 1.1000629781407885 1.0 17.05502328943578 -5.42338891336472 2.957410986159276 1.0674910828634494 0.8301980116634713 0.7508841660223122 0.05330060135187268 0.1146662557752997 1.9066866001242302 0.013654142309422333 0.032765199396975066 3.772342240674639e-06 5.42338891336472 -0.2372930711999781 LGIHEDSQNRK ddPTM_PC-9_Lapatinib_30min_R1 1 LGIHEDSQNRK 11 1 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 55.06399999999999 0.034292 14385000.0 136030.0 107570.0 148010.0 118580.0 137640.0 136770.0 106450.0 112640.0 142340.0 103080.0 False True 134090.187255153 107320.92827408115 135841.18913512255 127300.76877128411 129544.2858106515 130920.66592644194 111961.46013614985 117873.66561253682 126308.17029335056 120897.24065453386 1.109125291273754 0.8877037035175411 1.1236086812211976 1.0529667019865943 1.0715239248580266 1.0829086356118764 0.9260878042376652 0.9749905372064118 1.0447564362058397 1.0 16.883421791484977 -7.246843033476576 24.842754489963976 0.9843745674937401 1.0508779004672117 0.20027969392603018 0.0664382933160569 1274.24897652781 2168754.424858776 0.025192226697834805 0.019419047464216094 5.664439812005333e-08 7.246843033476576 0.06650333297347166 LGIHEDSTNR ddPTM_PC-9_AZD4547_30min_R2 6 LGIHEDSTNR 10 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 ;;;;; 198.61 0.00013794 201877100.0 378569.0 332145.0 608459.0 911816.0 717744.0 604297.0 476187.0 732259.0 492852.0 580689.0 False True 498946.0672756346 439504.37580051617 600390.4360999514 701610.9086167698 618097.6347632619 566510.2130609318 518566.7205035483 619105.1971878408 518903.1505427007 560359.2548579766 0.8904039024073812 0.7843260765130199 1.0714384225743192 1.2520733842338225 1.1030381481250258 1.0109768120177014 0.9254183204933045 1.1048362132338716 0.9260187032588889 1.0 19.09599253200531 -5.267575133654909 24.78179812981772 1.0563479669475744 0.837364983673694 0.4478071383515264 0.0938378544949373 359.91111162126487 1453656.6247974215 0.026066476385035536 0.05656513195709577 5.400386791088191e-06 5.267575133654909 -0.21898298327388033 LGIHEDSTNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LGIHEDSTNR 10 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 ;;;;; 172.98 0.00017953 140987000.0 460614.0 514674.0 691160.0 690429.0 794499.0 728895.0 726702.0 666642.0 682891.0 507087.0 False True 538586.8526588125 565767.4333580295 707639.8756388966 651746.5015310207 638822.6243087932 690670.463053687 657863.5256931338 649143.3538655842 692876.9889721551 599017.8590015158 0.8991165197588035 0.9444917624010235 1.1813335195355268 1.0880251594124366 1.066450047705801 1.1530047938886898 1.0982369153228688 1.0836794664980791 1.156688366732655 1.0 19.19223949032039 -5.137471997063574 5.398799641574156 1.1057569944988845 0.9106983725347622 0.6851661387288228 0.049520524895416404 0.10958203404158963 4.2890179452921435 0.011862145020665831 0.03327951846461376 7.286651567040748e-06 5.137471997063574 -0.19505862196412238 LGIHEDSTNR ddPTM_PC-9_Lapatinib_30min_R1 6 LGIHEDSTNR 10 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 ;;;;; 196.52 9.8454e-05 173257100.0 315692.0 282348.0 371248.0 306040.0 334857.0 347593.0 278073.0 287152.0 356466.0 278871.0 False True 311190.174189178 281694.24055340904 340725.4224987223 328547.20251951274 315161.3696141921 332727.2576688585 292470.25931836147 300494.1302199138 316317.04532660893 327073.4807777492 0.9514381094095362 0.8612567423184763 1.041739677850097 1.0045057818147138 0.9635797095648622 1.0172859532288132 0.8942035246113362 0.9187358434116019 0.9671130920624854 1.0 18.319255264424854 -4.736178304194762 0.002517941109019623 1.9086825052540515 9.504344716958126e-07 0.021112449811553025 0.053667533668855405 899098.6123469988 347.9126992218767 129421.1868752079 134340.55362226846 1.835784487861562e-05 4.736178304194762 -1.9086815548195797 LGIHEDSTNRR ddPTM_PC-9_AZD4547_30min_R2 2 LGIHEDSTNRR 11 1 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 ; 81.525 0.005935800000000001 42915000.0 43428.0 43176.0 87129.0 133312.0 97631.0 94100.0 72723.0 92443.0 72094.0 86021.0 False True 57237.200641484706 57131.797647301915 85973.61253092284 102578.97804986843 84076.62088373037 88215.9121243916 79195.20611688151 78158.05847881104 75904.74165718193 83009.4309727546 0.6895264787475911 0.6882567074342882 1.0357089733471505 1.2357508881555512 1.0128562489643622 1.0627215617626131 0.9540507047069748 0.9415563697149558 0.9144110586915771 1.0 16.340987634619644 -5.260268675648184 24.022730346912233 1.0242179809566536 0.6888915306891624 0.7115264378473325 0.08419685149430048 32.343142854977025 663638.6564282684 0.024035655028483965 0.05669875166605118 5.4920100633715915e-06 5.260268675648184 -0.3353264502674912 LGIHEDSTNRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LGIHEDSTNRR 11 1 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 ;;; 96.665 0.0022659000000000004 29008600.0 84425.0 93034.0 128899.0 145478.0 160670.0 144327.0 147220.0 141176.0 136257.0 102391.0 False True 98716.48503024255 102269.80067971381 131972.44101217948 137327.33930603997 129187.86687924566 136758.2380468372 133274.25581950098 137470.27958833624 138249.50085208134 120953.6777732901 0.8161511650375122 0.8455286566102068 1.0910990342893288 1.1353713407825423 1.0680772115205075 1.130666223338578 1.1018619547005755 1.1365531178473471 1.1429954293015359 1.0 16.88409511167213 -5.25607191349842 4.3497226115636405 1.1082875671873789 0.8231093420415746 0.8750283713173769 0.040850873946865464 0.05431063909089426 2.6731496855489416 0.0099824203459568 0.02576857623221573 5.545338817812487e-06 5.25607191349842 -0.28517822514580426 LGIHEDSTNRR ddPTM_PC-9_Lapatinib_30min_R1 3 LGIHEDSTNRR 11 1 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 ;; 74.173 0.0091785 40972200.0 161489.0 127658.0 180510.0 138558.0 174998.0 163723.0 120677.0 129820.0 181181.0 113568.0 False True 159186.13724654476 127362.41574428442 165669.1645887506 148748.01753593807 164704.96169930542 156720.94894695375 126925.06458290399 135851.91113121022 160774.48785948826 133198.07748015234 1.1951083698656602 0.9561880933548949 1.2437804488089308 1.1167429767002666 1.2365415838967186 1.1766006830714695 0.95290462883608 1.0199239636281787 1.2070330961304232 1.0 17.02321373379894 -7.234189470065499 24.91071195416719 1.0466257278950168 1.1512790777183985 0.23103568321941625 0.0974898679644228 1124.6588967794148 1028116.4127770764 0.037173361401129534 0.028785882515810008 5.8319061964093394e-08 7.234189470065499 0.1046533498233817 LGLDYEER ddPTM_PC-9_AZD4547_30min_R2 2 LGLDYEER 8 0 F5H3X6;F5GWA7;F5GY37;J3KPX7;Q99623-2;Q99623 F5H3X6 PHB2 Prohibitin-2 0 ; 133.6 0.017091 20951900.0 110796.0 110403.0 134430.0 195869.0 171542.0 148068.0 130912.0 162276.0 120478.0 128146.0 False True 146026.82330003506 146088.6107016645 132647.37036499823 150714.42819588372 147726.35433045716 138809.28455296988 142562.9143898521 137199.97293150914 126846.2211192882 123659.64754460685 1.180876916597711 1.181376573542044 1.0726811292030354 1.2187842290389643 1.1946205351844377 1.1225107568165937 1.1528652816063254 1.1094967166392578 1.025768903906441 1.0 16.916015273176463 -8.167020640350085 1.530935036267618 0.9967324463503161 1.162422186884471 0.7043232766448733 0.03812815338161 0.2176708786484685 0.9315030336714496 0.03580839472690479 0.011186125907909836 6.807370051074569e-09 8.167020640350085 0.16568974053415497 LGLDYEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGLDYEER 8 0 F5H3X6;F5GWA7;F5GY37;J3KPX7;Q99623-2;Q99623 F5H3X6 PHB2 Prohibitin-2 0 ; 114.28 0.016975 13363500.0 94922.0 95560.0 106193.0 117708.0 126673.0 99413.0 97362.0 95435.0 93109.0 79665.0 False True 110990.4198050421 105046.56526596106 108725.04385919512 111113.20237448496 101852.33497973901 94199.60727341552 88139.1665201619 92929.93237174075 94470.54298007788 94107.63387220685 1.1793986867820008 1.116238512686534 1.1553265063155018 1.1807033903898887 1.0822962047696265 1.0009773213651676 0.9365782869416331 0.9874855901481345 1.0038563195453818 1.0 16.52202413654014 -6.620827319030234 2.636469400630297 0.979826363571758 1.1542342427058148 0.9153455498711851 0.0247081313602936 0.07433817610161358 1.0486657716232046 0.009064953869929318 0.009126022455856656 2.394267558181783e-07 6.620827319030234 0.17440787913405675 LGLDYEER ddPTM_PC-9_Lapatinib_30min_R1 2 LGLDYEER 8 0 F5H3X6;F5GWA7;F5GY37;J3KPX7;Q99623-2;Q99623 F5H3X6 PHB2 Prohibitin-2 0 ; 131.03 0.01658 21051000.0 139387.0 127293.0 110846.0 90037.0 105786.0 99029.0 96240.0 76629.0 105669.0 78819.0 False True 137399.31581955464 126998.26087935861 101732.66975793365 96658.62133462713 99563.87546327797 94793.76051787399 101222.83629406334 80189.46308791792 93767.44447609974 92442.75913028407 1.4863177723407315 1.3738043095443937 1.100493653749093 1.045605110059528 1.0770327108363107 1.0254319690336864 1.0949785277547275 0.8674499100021777 1.0143297902213058 1.0 16.496272699979976 -5.168824729643837 1.4935709008766884 1.0124650974465568 1.5418441055955292 0.8905608540459258 0.05767699066866419 0.18588997064043056 0.6202037975564165 0.017846282106866753 0.1174476554382575 6.779150419127556e-06 5.168824729643837 0.5293790081489724 LGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSR ddPTM_PC-9_AZD4547_30min_R2 1 LGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSR 34 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 122.06 2.6172e-24 5316400.0 30958.0 28586.0 41952.0 38610.0 35077.0 44755.0 39238.0 50365.0 40983.0 39283.0 False True 40802.00003359776 37825.86547030231 41395.68906905017 29709.0610185536 30207.164023093188 41956.46277499635 42730.105985921895 42582.24652256317 43149.27771154727 37907.714126814644 1.0763508423932056 0.9978408443136793 1.0920122730314739 0.7837207202514594 0.7968606052593832 1.1068054020518676 1.1272139977360454 1.1233134865402479 1.1382716870555094 1.0 15.210203842722805 -6.889414252479809 17.064043694783635 1.1088368331367329 0.9507769246339098 0.35101546139760065 0.10138463466566144 1.4488119211849888 215.5644003579135 0.03857775588961798 0.0340226708790523 1.2899882292732804e-07 6.889414252479809 -0.15805990850282303 LGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSR 34 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ;;; 165.02 8.8187e-25 16426200.0 104629.0 147147.0 159568.0 133385.0 152888.0 118820.0 134392.0 100249.0 107928.0 95530.0 False True 122340.62318305338 161754.78169935528 163372.70628500954 125911.87089000437 122930.69391569131 112588.87002934443 121661.41684617863 97617.5699725957 109506.2428202842 112848.8327849363 1.084110665249026 1.4333757621367904 1.4477128584604861 1.1157569625018913 1.0893395251147056 0.9976963629204096 1.0780919380711458 0.8650295050781087 0.9703799332065551 1.0 16.784031970998527 -6.096767039077103 2.1558941311457387 0.9893710708462189 1.3292216565308659 0.6160993147267233 0.11169129328487518 0.20293343487774626 1.862270406362145 0.036648735417203926 0.05321660013856692 8.002634110700328e-07 6.096767039077103 0.339850585684647 LGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSR ddPTM_PC-9_Lapatinib_30min_R1 4 LGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSR 34 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ;;; 146.78 1.9583999999999998e-30 6646600.0 32764.199999999997 32578.0 33036.3 33260.4 40120.8 36575.5 34192.600000000006 34168.9 36758.4 29892.699999999997 False True 32296.976499781587 32502.567642586357 30320.18293780585 35706.48076944182 37760.973424527714 35011.25112665483 35962.925522323305 35756.511833702134 32618.28190888786 35059.61336548096 0.9212017304098563 0.9270657751915706 0.8648179494089497 1.0184505002156627 1.077050480588199 0.9986205712446976 1.0257650347545397 1.01987752862407 0.9303662755449326 1.0 15.097522465812933 -5.774014021036194 24.999980403297 1.0138210516152195 0.9066322163799766 0.6255376469251022 0.03736809974105024 138.0473939347395 274455.49245223537 0.010698133992823886 0.015990247757129254 1.6826197374397106e-06 5.774014021036194 -0.10718883523524292 LGLGIDEDEVAAEEPNAAVPDEIPPLEGDEDASR ddPTM_PC-9_Lapatinib_30min_R1 1 LGLGIDEDEVAAEEPNAAVPDEIPPLEGDEDASR 34 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 103.14 7.7005e-17 1517600.0 8242.3 7620.7 7542.1 6119.7 8739.9 8835.4 6294.6 8710.6 9532.5 6217.0 False True 8124.763290547302 7603.054737364409 6922.017651347924 6569.7631527207495 8225.836265304519 8457.530538323363 6620.503588285657 9115.326275608697 8458.849468324886 7291.600166368215 1.1142634134029963 1.0427141592915021 0.9493139356810932 0.9010043067121444 1.1281249763591503 1.1599004807384923 0.9079630584822899 1.250113290310711 1.1600813642169374 1.0 12.832019738275438 -6.29506937278012 24.75174125594826 1.106826330521533 1.0009939241030459 0.18258096378763355 0.10238922134934945 955.5509541225622 703284.761149386 0.03257913693718703 0.03694351658014869 5.069097297049444e-07 6.29506937278012 -0.10583240641848701 LGLGLDDESNNQQAAAT(ph)QSPGDSRR ddPTM_PC-9_AZD4547_30min_R2 2 LGLGLDDESNNQQAAATQSPGDSRR 25 1 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 1 LGLGLDDESNNQQAAAT(0.624)QS(0.361)PGDS(0.015)RR;LGLGLDDESNNQQAAAT(0.5)QS(0.5)PGDS(0.001)RR 85.51799999999999 8.5758e-06 6183000.0 13212.4 12635.6 17831.3 29145.2 19696.1 19070.9 13205.3 21076.6 15639.7 18113.9 True False 17413.668365007656 16719.810597374657 17594.84531123555 22426.22442885129 16961.636494433536 17878.393608215352 14380.546117944205 17819.695762085885 16466.382612919635 17479.73787444206 0.996220223100084 0.9565252475451289 1.006585192387913 1.2829840235557375 0.970359888476013 1.022806734096178 0.8226980416548849 1.0194486833890624 0.9420268616840016 1.0 14.093395929944139 -6.772349855007503 2.771034953783 0.9486385683322947 1.052854572978289 0.16613475993392968 0.09943109536610391 0.4888683193483407 7.701860226635092 0.03842664383658195 0.03543335326269644 1.6890797099322553e-07 6.772349855007503 0.10421600464599434 LGLGLDDESNNQQAAAT(ph)QSPGDSRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGLGLDDESNNQQAAATQSPGDSRR 25 1 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 1 LGLGLDDESNNQQAAAT(0.499)QS(0.499)PGDS(0.003)RR 117.38 6.0029e-06 0.0 6977.2 3396.7 4600.8 4870.5 5026.4 4459.7 6132.7 4538.2 3692.1 1536.1 True False 8158.3021540184645 3733.9019279917397 4710.5005206311625 4597.621675374051 4041.5130023143065 4225.825481146843 5551.766259096961 4419.077058620362 3746.089977733038 1814.5827702390907 4.49596584284966 2.057719267057605 2.595913836441037 2.533707335250552 2.227240922045013 2.328813846606758 3.059527705294731 2.435313026827705 2.064435990009676 1.0 10.825422149961009 -4.756742123824712 24.996386000642254 2.346516578491911 4.495969094422913 0.630433538450436 0.5103068086699385 90.810200350998 483187.3090457823 0.11850138873520058 0.9348935622051019 1.750886024344794e-05 4.756742123824712 2.1494525159310016 LGLGLDDESNNQQAAATQS(ph)PGDSRR ddPTM_PC-9_AZD4547_30min_R2 1 LGLGLDDESNNQQAAATQSPGDSRR 25 1 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 1 LGLGLDDESNNQQAAAT(0.282)QS(0.71)PGDS(0.007)RR 66.711 0.0074028 0.0 2154.7 1209.1 3091.2 4014.6 4936.9 2071.8 888.83 2893.1 2223.6 3400.5 True False 2839.8497794558134 1599.9179297608102 3050.2086682457993 3089.0959949517037 4251.496652097065 1942.2500184836874 967.9341481081335 2446.037871824235 2341.13495643063 3281.4495300316457 0.8654254022393654 0.48756438735944263 0.9295308796708458 0.9413815348005408 1.295615432505544 0.5918878229600432 0.29497151769352337 0.7454138329534649 0.7134453646184992 1.0 11.680117528723708 LGLGLDDESNNQQAAATQS(ph)PGDSRR ddPTM_PC-9_Lapatinib_30min_R1 1 LGLGLDDESNNQQAAATQSPGDSRR 25 1 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 1 LGLGLDDES(0.002)NNQQAAAT(0.288)QS(0.694)PGDS(0.017)RR 54.869 0.0030092 3709600.0 4818.0 3738.4 4915.6 4952.8 5731.0 5150.8 4516.3 3804.9 5404.5 3994.2 True False 4749.294436487008 3729.7439644866117 4511.458342764726 5317.045434056461 5393.913847579517 4930.512291101247 4750.131915574386 3981.689544470362 4795.788298091984 4684.592148063044 1.013811722852056 0.7961726115322041 0.9630418615268558 1.1350071182301154 1.151415892162514 1.052495529016306 1.013990495957784 0.8499543649956135 1.0237365701248755 1.0 12.193707733489955 -5.524201946316335 24.96467399433575 1.032527130058148 0.8986459240352277 0.2418607392609745 0.09143909074351211 56.95864092863443 1074627.342804664 0.026744097501282774 0.046795321710737386 2.9908735612575227e-06 5.524201946316335 -0.1338812060229203 LGLGS(ph)GT(ph)LLSVS(ph)EY(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 LGLGSGTLLSVSEYK 15 0 P59044-2;P59044 P59044-2 NLRP6 NACHT, LRR and PYD domains-containing protein 6 4 LGLGS(0.989)GT(0.991)LLS(0.041)VS(0.981)EY(0.999)K 45.207 0.035783999999999996 5563300.0 1381.6 0.0 1398.1 1308.2 1711.6 0.0 1975.5 4502.7 2109.0 0.0 True False 1820.9200609347718 0.0 1379.5602804976877 1006.6147014885217 1473.9738843665737 0.0 2151.3156729494035 3806.911176752609 2220.477434391167 0.0 0.0 LGLGTLS(ph)SSLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGLGTLSSSLSR 12 0 O95248;O95248-5;O95248-4 O95248 SBF1 Myotubularin-related protein 5 1 LGLGT(0.02)LS(0.585)S(0.365)S(0.029)LSR 109.39 0.0013182 2579300.0 15239.0 13238.0 16901.0 21902.0 20022.0 19302.0 20028.0 15788.0 17632.0 14731.0 True False 17818.66171603041 14552.181153105854 17303.983937399422 20674.90194724205 16098.832829129606 18289.76914077099 18130.802849836757 15373.581728768748 17889.834643533206 17401.61368946817 1.0239660547581657 0.8362546952707695 0.9943896150201383 1.188102570036648 0.9251344798484388 1.0510386833745395 1.0419035368432474 0.8834572473053559 1.028056073578999 1.0 14.08693347607442 -5.50353934250341 24.906393120222063 1.0168116823408377 0.9264133030077536 0.1341078966452688 0.08682393373425637 1317.8810503234763 1697240.7711808153 0.022496330883026015 0.04569867671487585 3.1366109733875854e-06 5.50353934250341 -0.09039837933308414 LGLHS(ph)LR ddPTM_PC-9_AZD4547_30min_R2 1 LGLHSLR 7 0 P61204-2;P84077;P61204;H0YGG7 P61204-2 ARF3;ARF1 ADP-ribosylation factor 3;ADP-ribosylation factor 1 1 LGLHS(1)LR 61.691 0.039661 2519800.0 22128.0 19552.0 24420.0 22750.0 26251.0 25372.0 21364.0 28758.0 22604.0 23504.0 True False 29164.2437090074 25871.801639800986 24096.174844255445 17505.338983996222 22606.50177524358 23785.484829118686 23265.354612448016 24314.111893097845 23798.801293019405 22681.132114060823 1.285837213166598 1.1406750557994483 1.0623885405313338 0.7718018172974731 0.9967095849342117 1.048690370017872 1.025758083655137 1.0719972782145508 1.0492774863855099 1.0 14.469205032818046 -5.023901975924922 2.2109159981920308 0.9989547958334297 1.2919944333736044 0.5543779588327011 0.08109635517861437 0.32254698511438623 2.5899265103909404 0.023804503374999775 0.15283358949560846 9.46450759500006e-06 5.023901975924922 0.2930396375401747 LGLHS(ph)LR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGLHSLR 7 0 P61204-2;P84077;P61204;H0YGG7 P61204-2 ARF3;ARF1 ADP-ribosylation factor 3;ADP-ribosylation factor 1 1 LGLHS(1)LR 75.043 0.024909999999999998 0.0 20171.0 21049.0 20834.0 21024.0 23206.0 20063.0 21099.0 18444.0 16571.0 16397.0 True False 23585.55190459016 23138.605612005234 21330.761573385003 19846.09344072765 18658.95088566486 19010.86096110704 19100.349976468224 17959.86454303336 16813.319525747993 19369.64630141942 1.2176552703939563 1.1945806986836731 1.1012468292630553 1.0245976169050293 0.9633088077760884 0.9814769286579028 0.986096993163398 0.927216959130392 0.8680240859388281 1.0 14.241509989461338 -5.523325263183569 0.8843312398105224 0.9429165611337174 1.2630307736455058 0.8958387734254296 0.03441516711298757 0.282052801481747 0.3456451332560326 0.014440380775590164 0.07093178849418093 2.9969171486781693e-06 5.523325263183569 0.3201142125117884 LGLHS(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 1 LGLHSLR 7 0 P61204-2;P84077;P61204;H0YGG7 P61204-2 ARF3;ARF1 ADP-ribosylation factor 3;ADP-ribosylation factor 1 1 LGLHS(1)LR 59.931000000000004 0.043693 2772200.0 22743.0 30724.0 32118.0 26943.0 32844.0 31566.0 30572.0 31131.0 28854.0 24805.0 True False 22418.68064944461 30652.86046567694 29477.382019065328 28924.478099213222 30912.18049378846 30215.99576393998 32154.868570055154 32577.459909302917 25604.158673909886 29092.511199415087 0.7705997084877068 1.053634052267486 1.0132292058603032 0.9942241802692768 1.0625476873378314 1.0386176551355073 1.1052627375357558 1.1197885148518185 0.8800944854297991 1.0 14.828360211518033 -4.75905636602044 24.997559798027623 1.0354958102331877 0.7705993624421689 0.5966091376430921 0.06375885233479883 42.81178664400781 448993.37645005016 0.015502612486826703 0.10123687984892898 1.7415808231998525e-05 4.75905636602044 -0.26489644779101884 LGLPLLTDCAQPS(ph)RPHGSPSR ddPTM_PC-9_AZD4547_30min_R2 1 LGLPLLTDCAQPSRPHGSPSR 21 1 U3KQ90;P55199 U3KQ90 ELL RNA polymerase II elongation factor ELL 1 LGLPLLTDCAQPS(0.743)RPHGS(0.242)PS(0.014)R 108.25 2.3878e-05 22231000.0 19697.0 16038.0 29035.0 43286.0 34864.0 27957.0 25050.0 35037.0 24041.0 29535.0 True False 25960.236276948584 21221.96985981629 28649.976928868036 33307.08146203344 30023.735396445558 26208.844370474206 27279.401471719855 29622.836720163716 25311.758179325767 28500.98863975435 0.9108538866872211 0.7446046917198871 1.005227477930568 1.1686289862792816 1.053427857396049 0.9195766751023168 0.9571387791674506 1.0393617251173024 0.8881010585022264 1.0 14.798724343771838 -5.2805246036401705 23.64570876685731 1.0083043719672584 0.8277293150138505 0.4230409867435093 0.08218385542536036 332.88266864756775 412426.2440166283 0.022441522999797042 0.046862964032798216 5.241739046803022e-06 5.2805246036401705 -0.18057505695340792 LGLPLLTDCAQPS(ph)RPHGSPSR ddPTM_PC-9_Lapatinib_30min_R1 1 LGLPLLTDCAQPSRPHGSPSR 21 1 U3KQ90;P55199 U3KQ90 ELL RNA polymerase II elongation factor ELL 1 LGLPLLTDCAQPS(0.46)RPHGS(0.46)PS(0.08)R 83.751 0.00020703 12808000.0 58113.0 50913.0 61351.0 44518.0 60785.0 57212.0 41522.0 45800.0 61311.0 42002.0 True False 57284.29796338102 50795.11407658541 56306.95760170856 47792.00222769455 57209.745807907995 54765.17612768592 43671.80599129367 47928.03520112026 54405.50954654781 49261.98973585298 1.16284986194314 1.0311218517350431 1.1430102174847443 0.9701598023944906 1.1613364810205915 1.1117126291759936 0.8865213570435472 0.9729212209680224 1.1044115318580274 1.0 15.588187280307036 -7.223048819929058 24.879651132214565 0.9887068867382449 1.0930091474115555 0.32496441210644034 0.07451473470684206 625.6051185082641 405434.5187344909 0.027927623594143334 0.021632244899423107 5.983443301723888e-08 7.223048819929058 0.10430226067331061 LGLPLLTDCAQPSRPHGS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 1 LGLPLLTDCAQPSRPHGSPSR 21 1 U3KQ90;P55199 U3KQ90 ELL RNA polymerase II elongation factor ELL 1 LGLPLLTDCAQPS(0.018)RPHGS(0.809)PS(0.173)R 87.51100000000001 0.00020925 20265000.0 19430.0 9550.9 24487.0 35143.0 28913.0 24332.0 23407.0 24207.0 26991.0 27887.0 True False 25608.335830893593 12638.041646970902 24162.28638047842 27041.324303937563 24898.929024708308 22810.51619352499 25490.177654632607 20466.364371521642 28417.689156781387 26910.684618142175 0.9516047694167324 0.46962913899450953 0.8978696277458922 1.0048545656734171 0.9252432399256905 0.8476378998603028 0.9472140161550585 0.7605293087833219 1.0560002303926244 1.0 14.715891473710048 -5.487377660419469 24.818027614105315 0.92337643069265 0.7038999530322699 0.3010415355025273 0.1338531456839063 587.4578184685049 410677.74792529404 0.03225080233821027 0.06708846158418996 3.2555347811634908e-06 5.487377660419469 -0.21947647766038003 LGLPLLTDCAQPSRPHGS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGLPLLTDCAQPSRPHGSPSR 21 1 U3KQ90;P55199 U3KQ90 ELL RNA polymerase II elongation factor ELL 1 LGLPLLT(0.001)DCAQPS(0.066)RPHGS(0.679)PS(0.255)R;LGLPLLTDCAQPS(0.376)RPHGS(0.523)PS(0.101)R 70.96 0.0010827999999999999 27321000.0 29853.6 38141.0 48761.0 45958.0 46183.0 45427.0 55093.0 53890.0 49877.0 37329.0 True False 34907.22484452296 41927.386414912406 49923.64716712229 43383.12225784635 37133.77267743947 43044.728150336945 49874.19220122112 52475.444601174764 50606.35676698644 44096.45220379858 0.7916107328361434 0.9508108775086599 1.1321465712568537 0.9838234163906097 0.8421034079072844 0.9761494632583835 1.1310250532337573 1.1900151141105724 1.1476287600893906 1.0 15.428374967443782 -7.232385576357126 4.847203430316155 1.1339884774056925 0.9503453036241596 0.4286887775278272 0.09621194557674664 0.19597345811826633 12.284148856139637 0.04058497371205606 0.02995256861006229 5.8561800887548724e-08 7.232385576357126 -0.18364317378153294 LGLPLLTDCAQPSRPHGSPS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 LGLPLLTDCAQPSRPHGSPSR 21 1 U3KQ90;P55199 U3KQ90 ELL RNA polymerase II elongation factor ELL 1 LGLPLLTDCAQPS(0.004)RPHGS(0.287)PS(0.709)R 87.05 0.00021089 23305000.0 26471.0 26180.0 54654.0 80585.0 52404.0 46611.0 40089.0 51537.0 38519.0 50919.0 True False 34888.22736899558 34642.17302219667 53929.252249710815 62007.37327583898 45128.609158884035 43696.40680159434 43656.84333731644 43573.14085244395 40555.03570190295 49136.34130853738 0.7100290017509665 0.7050214179495214 1.097543097705988 1.2619452654498977 0.9184364964316745 0.8892889791532391 0.8884838019010404 0.8867803277993179 0.8253572533463446 1.0 15.584502818190954 -5.242731520464886 24.20407504740088 0.9695871583530287 0.7075250936022149 0.43184717547775786 0.12086548550249991 576.5728315377596 745960.4243285707 0.03467197645598608 0.09132834682990368 5.718320322593084e-06 5.242731520464886 -0.26206206475081373 LGLPLLTDCAQPSRPHGSPS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 LGLPLLTDCAQPSRPHGSPSR 21 1 U3KQ90;P55199 U3KQ90 ELL RNA polymerase II elongation factor ELL 1 LGLPLLT(0.001)DCAQPS(0.236)RPHGS(0.328)PS(0.435)R 56.906000000000006 0.007132899999999999 15411000.0 11787.0 10200.0 12469.0 10932.0 13337.0 12876.0 11066.0 10004.0 10485.0 9060.0 True False 11618.91521852893 10176.382526686133 11443.846951731908 11735.97574808295 12552.543881550859 12325.323495422006 11638.943333646157 10468.822361397537 9304.068888055224 10626.008928308845 1.0934411308064003 0.9576862390520999 1.076965681935788 1.104457546315158 1.1813037205445511 1.159920302963985 1.095325950897589 0.9852073748505381 0.8755939272051778 1.0 13.375312209671591 -7.8670575129311535 3.79677396896067 0.9357685754369331 1.0958963456210438 0.5281669619531857 0.06239295233152448 0.1936545348285821 5.191023443607683 0.04168918299145493 0.018589491960239294 1.3581335791964115e-08 7.8670575129311535 0.16012777018411062 LGLVLQPDAGGLFLSHES(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGLVLQPDAGGLFLSHESPK 20 0 F5H212;P15822 F5H212 HIVEP1 Zinc finger protein 40 1 LGLVLQPDAGGLFLS(0.011)HES(0.989)PK 129.08 1.692e-05 1398900.0 5954.8 6938.6 4443.1 5762.4 7652.2 6737.9 7260.6 5334.3 5674.9 4263.2 True False 6962.830027338927 7627.418352390108 4549.040354550582 5439.551409952866 6152.806341777323 6384.552662604957 6572.823405808108 5194.280277158035 5757.884676643976 5036.084412527367 1.382588030101072 1.5145533171399477 0.9032891393231511 1.0801152173744084 1.2217440848433927 1.267761248545248 1.3051455987231013 1.0314124728007243 1.14332568817177 1.0 12.29808674971147 -5.241127174206098 24.988806011018895 1.1344485261495585 1.448570726305178 0.5365424255570301 0.1218179654045029 677.1305134869266 833027.5748356801 0.032568322802301757 0.0859257939785379 5.739483686228468e-06 5.241127174206098 0.3141222001556194 LGLVS(ph)PESMDNYSHFHELR ddPTM_PC-9_AZD4547_30min_R2 2 LGLVSPESMDNYSHFHELR 19 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 LGLVS(0.899)PES(0.099)MDNYS(0.001)HFHELR;LGLVS(0.5)PES(0.5)MDNYSHFHELR 73.168 0.0019881 10893100.0 15236.4 13829.400000000001 24825.0 37805.0 27993.0 31467.0 18857.699999999997 37027.0 21968.0 29081.0 True False 20081.258263192347 18299.48310134327 24495.804279633154 29089.64133142756 24106.655144352335 29499.363515602934 20535.998767794474 31305.327945814493 23129.183631439122 28062.883041567493 0.7155807275199576 0.6520884926269901 0.8728897969374463 1.0365877692730003 0.8590227564518197 1.0511879150801322 0.7317850677485989 1.115542116590238 0.8241912848790182 1.0 14.776375611461976 -5.382963850133615 4.125405452922768 0.9429251343693874 0.684844790945296 0.46404419170579314 0.11052103823184979 0.17783436599961888 5.041479196943819 0.02697911313354865 0.06017053820628622 4.140341368183084e-06 5.382963850133615 -0.25808034342409136 LGLVS(ph)PESMDNYSHFHELR ddPTM_PC-9_Lapatinib_30min_R1 1 LGLVSPESMDNYSHFHELR 19 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 LGLVS(0.951)PES(0.047)MDNYS(0.002)HFHELR 57.93600000000001 0.0099072 3153700.0 11065.0 7570.9 13958.0 6783.5 9255.0 13254.0 10233.0 9582.6 14435.0 10691.0 True False 10907.211070927518 7553.370046204709 12810.427119438124 7282.381219092633 8710.63909603009 12687.157316583049 10762.81466954646 10027.842579001195 12809.178292711214 12538.92510513795 0.8698681090660777 0.6023937445092196 1.0216527343471349 0.5807819376884709 0.6946878638313916 1.0118217638435656 0.8583522574144963 0.7997370185178142 1.0215531383517495 1.0 13.6141260584746 -6.75418287344059 24.99801324304656 0.9207801170545072 0.75072119102654 0.3109618191820205 0.13597363728138978 226.07150879572825 778794.9577909757 0.04408150425145695 0.0432199989618248 1.7612342668021386e-07 6.75418287344059 -0.17005892602796724 LGMLS(ph)PEGTCK ddPTM_PC-9_AZD4547_30min_R2 5 LGMLSPEGTCK 11 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 1 LGMLS(0.999)PEGT(0.001)CK;LGMLS(0.976)PEGT(0.024)CK;LGMLS(1)PEGTCK;LGMLS(0.993)PEGT(0.007)CK;LGMLS(0.998)PEGT(0.002)CK 114.76 0.0014259000000000001 103607000.0 463545.0 505578.0 581990.0 739246.0 626470.0 627553.0 543012.0 635830.0 506117.0 603433.0 True False 610942.6676650313 668996.201383352 574272.4323344888 568824.2559368464 539495.4541593415 588312.0117045543 591339.0160463703 537577.0834198634 532869.3113616661 582306.9943407109 1.0491762482721707 1.1488720003110915 0.9862021887349665 0.9768459961242099 0.9264794333617086 1.010312459617014 1.015510755998879 0.9231850014587394 0.9151003105586628 1.0 19.151420422146614 -5.373348369356816 5.522962514938906 0.9669777690918785 1.0980406360472232 0.6184945491649823 0.04094070689979587 0.1363627107578125 5.68519016830802 0.01099288942220314 0.02345675557073416 4.23303277066091e-06 5.373348369356816 0.13106286695534475 LGMLS(ph)PEGTCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LGMLSPEGTCK 11 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 1 LGMLS(0.998)PEGT(0.002)CK;LGMLS(1)PEGTCK;LGMLS(0.997)PEGT(0.003)CK;LGMLS(0.983)PEGT(0.017)CK;LGMLS(0.997)PEGT(0.003)CK 94.465 0.0058311000000000005 159344700.0 757903.0 771377.0 672153.0 887220.0 859013.0 802811.0 874737.0 796773.0 716533.0 624614.0 True False 886201.008633416 847954.2107070058 688179.6766744462 837511.9398060486 690695.5691264174 760710.177892005 791875.578812544 775858.5530007754 727010.9395777441 737851.5737582962 1.201055930692798 1.1492205761490681 0.932680367094912 1.1350683112866802 0.9360901212262969 1.0309799490123426 1.0732179844505487 1.0515103316089551 0.9853078389121885 1.0 19.49297110733633 -5.08208598557519 5.974711929061841 1.0238764480559022 1.1893620517670147 0.5432536793346345 0.058225190727109716 0.14400729527495018 8.169558906882148 0.014026843524812932 0.039200095877466624 8.277782564119367e-06 5.08208598557519 0.16548560371111254 LGMLS(ph)PEGTCK ddPTM_PC-9_Lapatinib_30min_R1 8 LGMLSPEGTCK 11 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 1 LGMLS(0.986)PEGT(0.014)CK;LGMLS(0.999)PEGT(0.001)CK;LGMLS(1)PEGTCK;LGMLS(0.995)PEGT(0.005)CK;LGMLS(0.986)PEGT(0.014)CK;LGMLS(0.997)PEGT(0.003)CK;LGMLS(0.807)PEGT(0.193)CK;LGMLS(0.996)PEGT(0.004)CK 142.19 0.00013857 178247300.0 1174867.0 1260802.0 1294434.0 1203854.0 1304358.0 1294890.0 1208573.0 1102561.0 1382582.0 929841.0 True False 1158113.1811357816 1257882.690432447 1188010.6331797368 1292389.4390992182 1227638.2269064942 1239510.57323602 1271146.996346895 1153790.0091568206 1226861.0559261017 1090562.7779147462 1.0619408663022571 1.1534252918824457 1.089355566904016 1.1850665227822856 1.125692396410089 1.1365788364848426 1.165588100097678 1.0579767002161677 1.1249797634501795 1.0 20.05664138999466 -9.129703034449141 0.7895975037068116 0.9989763112837482 1.1297215653171322 0.46123044588816764 0.03975194706696301 1.8238538394384596 1.656794522284541 0.04271844500280307 0.012995049527003536 7.418173140276654e-10 9.129703034449141 0.130745254033384 LGNAGDVCVPQAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 LGNAGDVCVPQASPR 15 0 Q9H0W5 Q9H0W5 CCDC8 Coiled-coil domain-containing protein 8 1 LGNAGDVCVPQAS(1)PR;LGNAGDVCVPQAS(1)PR 117.53 0.0018685 0.0 16211.5 13726.3 20936.0 29035.0 28418.0 27875.0 23252.1 26939.0 24223.0 23972.0 True False 21366.41977985237 18163.058042573655 20658.374960660618 22341.429336278266 24472.65123038634 26131.971843437 25321.491854713662 22776.19654663615 25503.37832776538 23132.747576508915 0.9236438390720939 0.7851664823861246 0.8930359393035958 0.9657922934742856 1.0579223738747785 1.12965274691251 1.0946167017543302 0.9845867409959188 1.1024794284991817 1.0 14.497649010832195 -5.944185623534304 2.120533227950947 1.0660610347366841 0.8530893247107028 0.7354060479785541 0.05247093368782162 0.1518927069596053 1.3821214088681844 0.01643447586083732 0.026982900345754925 1.1371411519116465e-06 5.944185623534304 -0.21297171002598136 LGNDFHTNKR ddPTM_PC-9_AZD4547_30min_R2 1 LGNDFHTNKR 10 1 H3BNC9;P08708;H0YN88;A0A075B716;H0YN73;A0A0J9YYC4 H3BNC9 RPS17 40S ribosomal protein S17 0 51.276 0.044153 14900000.0 93657.0 72523.0 121940.0 164790.0 141370.0 112900.0 102940.0 126060.0 95679.0 114220.0 False True 123437.97781338138 95964.64148543813 120322.99592581947 126800.21148012023 121743.21572382734 105840.34515243203 112101.46057879609 106580.32357062073 100736.39660745006 110221.19256586218 1.119911470197726 0.8706550823072876 1.0916502818087457 1.1504158912484215 1.1045354608287352 0.9602540372550189 1.0170590425413004 0.9669676138455329 0.9139476198940188 1.0 16.750042116405474 -6.773448466915496 24.97678302080742 0.9724194573268082 1.0624569906531045 0.28654005492797374 0.07536489041035663 340.61234434471214 708408.9373646547 0.027970249301636375 0.024853442960173455 1.6848123335860618e-07 6.773448466915496 0.09003753332629627 LGNDFHTNKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGNDFHTNKR 10 1 H3BNC9;P08708;H0YN88;A0A075B716;H0YN73;A0A0J9YYC4 H3BNC9 RPS17 40S ribosomal protein S17 0 67.704 0.017023 12409000.0 69941.0 56172.0 69013.0 86751.0 88905.0 79895.0 92283.0 85156.0 78495.0 64166.0 False True 81780.62990228234 61748.38493218476 70658.53165326014 81890.62272053666 71484.70345988244 75705.1655528908 83541.2861689378 82920.74523023998 79642.84087704943 75798.78786222344 1.078917383889197 0.8146355195603185 0.932185509109901 1.0803684996834793 0.9430850476107541 0.9987648574340949 1.102145410567615 1.0939587237326518 1.0507139114389688 1.0 16.20988715724474 -6.619800601230579 0.9627346875319079 1.0669028929975775 0.9459555200189684 0.20105282471867247 0.07783186900414346 0.7597685996417763 1.5289919916940062 0.0432103859950893 0.04592003467712209 2.3999345543752185e-07 6.619800601230579 -0.12094737297860902 LGNPYCSPT(ph)LVR ddPTM_PC-9_AZD4547_30min_R2 2 LGNPYCSPTLVR 12 0 Q6ZV89;Q6ZV89-2 Q6ZV89 SH2D5 SH2 domain-containing protein 5 1 LGNPYCS(0.104)PT(0.896)LVR;LGNPYCS(0.093)PT(0.907)LVR 126.1 0.00066898 21315800.0 40988.0 43769.0 57083.0 74153.0 67613.0 62300.0 53643.0 76974.0 55790.0 60002.0 True False 54021.33139663751 57916.47330055484 56326.04212263041 57058.171502429504 58226.102035333635 58404.37115143047 58417.123079739256 65079.4369865538 58738.9455024576 57901.348243187414 0.9329891796257712 1.000261221160238 0.9727932739330927 0.9854377010839792 1.0056087431812857 1.0086875854104527 1.0089078208401223 1.1239710120948858 1.0144659370581883 1.0 15.821309321565588 -6.807362993030108 1.0509203287461275 1.0482271614230054 0.9721512777732267 0.37815041226860757 0.0360723804197964 0.496227634162717 1.1657273106949897 0.019994673614515505 0.01730759429457966 1.5582495386038636e-07 6.807362993030108 -0.07607588364977869 LGNPYCSPT(ph)LVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGNPYCSPTLVR 12 0 Q6ZV89;Q6ZV89-2 Q6ZV89 SH2D5 SH2 domain-containing protein 5 1 LGNPYCS(0.098)PT(0.902)LVR 129.54 0.00042161 6226300.0 24291.0 28355.0 36829.0 32390.0 30126.0 29619.0 35092.0 38566.0 32816.0 25683.0 True False 28402.986530880935 31169.897008333337 37707.14303476029 30575.29330979684 24223.026561300507 28065.727498730485 31767.831715921282 37553.683364054676 33295.87191822741 30339.124593483863 0.9361834565583094 1.0273828736320199 1.2428553407522807 1.0077842956735708 0.7984088824534854 0.9250671492597499 1.04709124411402 1.2377971964332923 1.0974565800550022 1.0 14.888891838144945 -7.530752097475348 24.204113265691767 1.1290650270917255 0.994234816691616 0.17283975310403354 0.11793050071459966 225.416783491834 692955.1390967447 0.06022532325114947 0.03486310022336103 2.946102838499032e-08 7.530752097475348 -0.13483021040010956 LGNPYCSPT(ph)LVR ddPTM_PC-9_Lapatinib_30min_R1 1 LGNPYCSPTLVR 12 0 Q6ZV89;Q6ZV89-2 Q6ZV89 SH2D5 SH2 domain-containing protein 5 1 LGNPYCS(0.117)PT(0.883)LVR 127.3 0.0005826000000000001 12242000.0 40455.0 51665.0 49773.0 45991.0 47160.0 42492.0 36766.0 41513.0 51430.0 32784.0 True False 39878.10428146159 51545.372866788166 45680.85606933616 49373.3315614785 44386.1415201274 40674.716213689964 38669.56358258038 43441.84553065732 45637.4118180906 38450.67071806588 1.037123762387974 1.3405584845252074 1.1880379513867156 1.2840694489701232 1.154365858675978 1.0578415266649466 1.0056928230490307 1.1298072236291672 1.1869080815968203 1.0 15.23072114374924 -6.546173311377849 4.70327723212348 1.0808975428455527 1.220306578311886 0.3407079547923567 0.08922254879539042 0.21813234074445503 12.188290342733689 0.02892502336406038 0.02986232844383173 2.843326211328894e-07 6.546173311377849 0.13940903546633332 LGNS(ph)RR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGNSRR 6 1 A0A0U1RQV5 A0A0U1RQV5 1 LGNS(1)RR 41.208 0.04457 1763100.0 15572.0 20168.0 20044.0 27919.0 31560.0 25300.0 27247.0 20294.0 22324.0 14782.0 True False 18208.032038980604 22170.145754331388 20521.924977293296 26354.78894461927 25376.04455535565 23973.223461895457 24665.96690880278 19761.304003270383 22650.446267141277 17461.85958575239 1.0427315572871194 1.2696325752396163 1.1752428128581276 1.5092773375707857 1.4532269275639267 1.3728906331062167 1.4125624357286906 1.1316838224603623 1.2971382661685356 1.0 14.091919585268576 -8.908775662138702 1.0104091641287771 1.00213916976188 1.316804255326911 0.2849731850880969 0.14022752810822983 1.7627175978189953 2.988611948420301 0.1430953429346219 0.04572146387863856 1.2337419667247364e-09 8.908775662138702 0.31466508556503103 LGNSGAS(ph)PSSAGK ddPTM_PC-9_AZD4547_30min_R2 2 LGNSGASPSSAGK 13 0 Q8IWI9-3;Q8IWI9 Q8IWI9-3 MGA MAX gene-associated protein 1 LGNSGAS(0.994)PS(0.006)SAGK;LGNS(0.002)GAS(0.968)PS(0.029)S(0.001)AGK 142.19 8.0463e-05 57973000.0 55479.0 61890.0 85195.0 100059.0 83563.0 75581.0 64406.0 79044.0 65862.0 74257.0 True False 73120.167965113 81894.73217508598 84065.25863457592 76991.94344613969 71961.71985237444 70854.90812193058 70138.00922904545 66829.56605042149 69343.3308600621 71657.28503207157 1.0204149924517332 1.1428668018671437 1.1731571827895926 1.074446839727189 1.0042484838794357 0.9888025772985696 0.97879802727181 0.932627659846597 0.9677080401389221 1.0 16.12882576296738 -6.279241799486806 2.2831310445217534 0.9705894048306988 1.1160872737472818 0.7016845495506855 0.04032710723095379 0.16679530100035167 1.7090107814420323 0.013953182373086173 0.017636684124174504 5.257244804831314e-07 6.279241799486806 0.145497868916583 LGNSGAS(ph)PSSAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LGNSGASPSSAGK 13 0 Q8IWI9-3;Q8IWI9 Q8IWI9-3 MGA MAX gene-associated protein 1 LGNSGAS(0.985)PS(0.01)S(0.005)AGK;LGNSGAS(0.823)PS(0.149)S(0.028)AGK;LGNS(0.001)GAS(0.997)PS(0.002)SAGK 135.47 5.1068e-05 35164400.0 84842.0 86632.0 95010.0 100195.0 118481.0 99873.0 100809.0 99858.0 90543.0 73648.0 True False 99204.07489411724 95232.25242905796 97275.39872743134 94581.39898657294 95265.4985729749 94635.48406363188 91259.64172604303 97236.83330829683 91867.02008447278 86999.79940275286 1.1402793520806462 1.0946261150349803 1.1181106093947308 1.0871450237341602 1.0950082555013396 1.0877666927199536 1.048963817762037 1.1176673276929423 1.0559451943008262 1.0 16.408724454062686 -14.522878745195813 0.0953531643345837 0.6962353913624926 1.163615196855156 0.7122448126629708 0.020629921930419768 108.1143278274656 0.7058312646797397 6.571511192990288 0.3931295594824588 3.000000000583875e-15 14.522878745195813 0.46737980549266345 LGNSGAS(ph)PSSAGK ddPTM_PC-9_Lapatinib_30min_R1 1 LGNSGASPSSAGK 13 0 Q8IWI9-3;Q8IWI9 Q8IWI9-3 MGA MAX gene-associated protein 1 LGNSGAS(0.904)PS(0.084)S(0.012)AGK 100.23 0.0023076 28861000.0 52325.0 40710.0 43705.0 35287.0 42236.0 44361.0 40545.0 42454.0 40902.0 30280.0 True False 51578.835904770196 40615.73849621494 40111.743606178796 37882.12369398124 39751.76151917091 42463.78344054178 42644.221711791375 44426.567825946695 36295.186042845475 35513.85765443617 1.4523580177251538 1.1436588751191739 1.1294673757067415 1.0666856882344133 1.1193309920305254 1.1956961660918712 1.2007769509788673 1.2509642928187275 1.022000662277017 1.0 15.116094459611087 -4.761422163039368 6.624687654152293 1.1353652464500736 1.4606909145611295 0.624045728769415 0.07580615371155544 0.07935738075133963 17.257676391353403 0.01873241336761932 0.11643528139366305 1.7321194441618042e-05 4.761422163039368 0.3253256681110559 LGPELSPSPT(ph)SPTATSTTPSR ddPTM_PC-9_AZD4547_30min_R2 1 LGPELSPSPTSPTATSTTPSR 21 0 M0QY76;P26651 M0QY76 ZFP36 Tristetraprolin 1 LGPELSPS(0.018)PT(0.559)S(0.418)PT(0.005)ATSTTPSR 103.73 0.00024833 6465000.0 10210.0 8929.1 13502.0 18987.0 15709.0 14777.0 11423.0 15254.0 10867.0 16111.0 True False 13456.567618807183 11815.256956932632 13322.954657949913 14609.840496225766 13528.076507077883 13852.991854007842 12439.624870716803 12896.844802048627 11441.407434579796 15546.958793806745 0.8655434028787491 0.7599722308159287 0.8569492487017601 0.9397233690518118 0.8701429447710957 0.891041909722324 0.8001323625860658 0.8295413252903319 0.7359257579776678 1.0 13.924344775841194 -5.480030216849858 24.36136825370402 0.8610405539788107 0.8116834981685888 0.07581004156725335 0.07239773046367018 981.9664736160336 558290.636533082 0.01884518080062265 0.039224074227356465 3.3110808321772195e-06 5.480030216849858 -0.049357055810221984 LGPELSPSPT(ph)SPTATSTTPSR ddPTM_PC-9_Lapatinib_30min_R1 1 LGPELSPSPTSPTATSTTPSR 21 0 M0QY76;P26651 M0QY76 ZFP36 Tristetraprolin 1 LGPELSPS(0.009)PT(0.492)S(0.492)PT(0.005)AT(0.002)STTPSR 135.43 3.6099000000000005e-09 0.0 7362.5 7929.8 7841.9 5159.0 12606.0 11635.0 13088.0 12331.0 13275.0 8486.4 True False 7257.509399882859 7911.439035305463 7197.169252609385 5538.410069919496 11864.539864349568 11137.398172509711 13765.632599924174 12903.943276528687 11779.829708052745 9953.262932582802 0.7291588144551895 0.794858840652821 0.7230964660894144 0.556441652092709 1.192025162473107 1.1189695527936419 1.3830271231820146 1.2964535714500818 1.1835143698947739 1.0 13.28095383996322 -6.2747719016596415 23.712363720837523 1.2160210562825189 0.7091873474198166 0.8258168843602945 0.11105862651456658 152.12993793651776 270567.7847844056 0.03489624890182241 0.03982885541390207 5.311633463848799e-07 6.2747719016596415 -0.5068337088627023 LGPGGLDDRY(ph)SLVSEQLEPAATSTYR ddPTM_PC-9_AZD4547_30min_R2 2 LGPGGLDDRYSLVSEQLEPAATSTYR 26 1 Q9Y446;Q9Y446-2;E9PKC4;E9PK71;E9PQ15;E9PJR7;E9PRW6 Q9Y446 PKP3 Plakophilin-3 1 LGPGGLDDRY(0.897)S(0.103)LVSEQLEPAATSTYR;LGPGGLDDRY(0.688)S(0.312)LVSEQLEPAATSTYR 190.63 1.9738e-23 22581000.0 14438.800000000001 17038.9 24626.0 45753.0 37182.0 36968.0 22131.0 31592.0 27014.0 31760.0 True False 19030.03805430297 22546.391211149992 24299.443149657433 35205.35272680349 32019.921108038066 34656.3851159885 24100.616126572124 26710.182311939152 28441.90488982597 30648.09206699165 0.620920806838692 0.7356539898753671 0.7928533722928944 1.1486963902956968 1.044760666929864 1.1307844233903823 0.7863659530222036 0.8715120749949172 0.928015513254681 1.0 14.903509644292086 -5.564369722513988 6.246827829542083 0.982088121496046 0.6978446514992068 0.5837581527481932 0.10729914251257797 0.1408249192637212 14.120022633401069 0.03237088161349655 0.05742519048619147 2.72665554475127e-06 5.564369722513988 -0.28424346999683914 LGPGGLDDRY(ph)SLVSEQLEPAATSTYR ddPTM_PC-9_Lapatinib_30min_R1 1 LGPGGLDDRYSLVSEQLEPAATSTYR 26 1 Q9Y446;Q9Y446-2;E9PKC4;E9PK71;E9PQ15;E9PJR7;E9PRW6 Q9Y446 PKP3 Plakophilin-3 1 LGPGGLDDRY(0.708)S(0.292)LVSEQLEPAATSTYR 111.99 9.5804e-10 6119000.0 12334.0 7373.0 15840.0 7126.7 12770.0 9393.8 10072.0 8522.9 12846.0 9122.5 True False 12158.11489822142 7355.928271495766 14537.696344168215 7650.821291974268 12018.89370678598 8992.04907201734 10593.478877325508 8918.905048376148 11399.14820562302 10699.311970032826 1.136345489530026 0.6875141403576811 1.3587505799331892 0.7150760080090267 1.1233333265212853 0.8404324593210036 0.9901084207093184 0.8335961296723254 1.0654094616130767 1.0 13.385230405209837 LGPGGLDDRYS(ph)LVSEQLEPAATSTYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGPGGLDDRYSLVSEQLEPAATSTYR 26 1 Q9Y446;Q9Y446-2;E9PKC4;E9PK71;E9PQ15;E9PJR7;E9PRW6 Q9Y446 PKP3 Plakophilin-3 1 LGPGGLDDRY(0.285)S(0.715)LVSEQLEPAATSTYR;LGPGGLDDRY(0.316)S(0.684)LVSEQLEPAATSTYR 147.08 3.2082e-12 11639500.0 14263.5 8991.5 22595.0 16353.8 29200.0 26080.0 24778.0 23882.0 26741.0 18418.0 True False 16678.028833033648 9884.116697246662 23133.75049201468 15437.54960573496 23478.469613953872 24712.318888783935 22430.848462814818 23255.122805070638 27132.036535998268 21757.037603192217 0.7665578897830571 0.4542951516430919 1.0632766700104646 0.7095428103442697 1.0791206984221549 1.135831051059916 1.0309697888063465 1.0688552012089467 1.2470464513982098 1.0 14.409194514900149 -5.767757197199161 0.8591038799304137 1.110532975476221 0.599318757011776 0.5490713637483671 0.15199663247237546 0.5700143091673864 0.7640252029829898 0.06383070920146713 0.21057999133135455 1.7070364821754598e-06 5.767757197199161 -0.511214218464445 LGPGGLDDRYS(ph)LVSEQLEPAATSTYR ddPTM_PC-9_Lapatinib_30min_R1 1 LGPGGLDDRYSLVSEQLEPAATSTYR 26 1 Q9Y446;Q9Y446-2;E9PKC4;E9PK71;E9PQ15;E9PJR7;E9PRW6 Q9Y446 PKP3 Plakophilin-3 1 LGPGGLDDRY(0.434)S(0.56)LVS(0.006)EQLEPAATSTYR 111.44 1.26e-10 6241300.0 8857.6 7165.7 8858.7 6894.5 9446.1 8757.1 6743.9 6878.9 10971.0 4724.0 True False 8731.288999715096 7149.108261909293 8130.37188157089 7401.544529377782 8890.498969747145 8382.579246797144 7093.0661438438765 7198.518806659086 9735.33045024834 5540.537105665668 1.5758921622935465 1.2903276569700661 1.4674338834870173 1.335889353003173 1.604627638113976 1.5129542654312789 1.2802127318289442 1.2992456632585299 1.757109512053108 1.0 12.43581012413515 -11.063427688941157 3.2097332294037475 0.9850570773925661 1.4459344058053463 0.45012660101073854 0.15138065684729765 96849278.43484148 115217516.65954335 12517194.795421615 0.036691079468749915 8.641165261533222e-12 11.063427688941157 0.4608773284127802 LGPGRPLPTFPTSECT(ph)SDVEPDTR ddPTM_PC-9_AZD4547_30min_R2 3 LGPGRPLPTFPTSECTSDVEPDTR 24 1 H0YHZ9;Q8TDD1;Q8TDD1-2 H0YHZ9 DDX54 ATP-dependent RNA helicase DDX54 1 LGPGRPLPTFPT(0.001)S(0.014)ECT(0.492)S(0.492)DVEPDT(0.001)R;LGPGRPLPTFPT(0.005)S(0.018)ECT(0.488)S(0.488)DVEPDTR;LGPGRPLPTFPT(0.02)S(0.051)ECT(0.464)S(0.464)DVEPDT(0.001)R 70.12100000000001 0.00055217 51991000.0 69115.0 57626.5 75985.0 102834.0 92663.0 77361.0 68129.0 85495.0 77331.0 84890.0 True False 91092.1323186935 76253.1391773726 74977.38925228303 79127.21006946238 79798.34192980823 72523.60444054281 74192.34901663887 72283.71222965416 81418.55878563451 81918.02693850517 1.1119912884019438 0.9308468725035929 0.9152733782097512 0.9659315907213217 0.9741243156370434 0.885319228879687 0.9056901367062238 0.8823907866325521 0.9939028297978222 1.0 16.321893346836653 -4.76081644421167 24.99629278086035 0.9340364531680965 1.1119914924388357 0.6133911129061773 0.04094617582694781 9.80634588203314 393184.5840711677 0.010081752012880791 0.058436115785576635 1.7345369497876927e-05 4.76081644421167 0.1779550392707392 LGPGRPLPTFPTSECT(ph)SDVEPDTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGPGRPLPTFPTSECTSDVEPDTR 24 1 H0YHZ9;Q8TDD1;Q8TDD1-2 H0YHZ9 DDX54 ATP-dependent RNA helicase DDX54 1 LGPGRPLPTFPT(0.001)S(0.002)ECT(0.498)S(0.498)DVEPDTR;LGPGRPLPT(0.001)FPT(0.031)S(0.112)ECT(0.428)S(0.428)DVEPDTR 71.042 0.00047558 17076900.0 11527.900000000001 15196.5 16641.5 17896.6 19961.7 19531.7 18267.4 20448.4 19130.9 13741.3 True False 13479.345783596498 16705.108089830275 17038.2964732402 16893.91152356006 16050.348181262445 18507.42326840724 16536.979627476925 19911.651166870713 19410.65322039301 16232.488913929043 0.8303930380035509 1.0291156321379453 1.049641651602774 1.040746838832796 0.9887792479864068 1.140146983407214 1.0187581038965996 1.2266542285936566 1.1957903266292575 1.0 13.986596603618063 -3.32192802701441 0.4748717627195575 1.1179502887948505 7.581924568350978e-14 0.48133909030453415 0.07773990254563633 15.890518607178118 0.9297563256604325 0.04817883326845836 13.418801713189591 0.00047650994936074135 3.32192802701441 -1.1179502887947748 LGPGRPLPTFPTSECT(ph)SDVEPDTR ddPTM_PC-9_Lapatinib_30min_R1 2 LGPGRPLPTFPTSECTSDVEPDTR 24 1 H0YHZ9;Q8TDD1;Q8TDD1-2 H0YHZ9 DDX54 ATP-dependent RNA helicase DDX54 1 LGPGRPLPTFPTS(0.001)ECT(0.5)S(0.5)DVEPDTR;LGPGRPLPTFPT(0.006)S(0.116)ECT(0.439)S(0.439)DVEPDTR 72.383 0.000364 49396000.0 51597.0 55386.0 55385.0 55122.0 64567.0 69838.0 55756.0 57238.0 65873.0 52443.0 True False 50861.217318269024 55257.75711990569 50831.459092282596 59175.855761601575 60769.296003606076 66851.19154032953 58642.77286379673 59897.48643759213 58453.689066558065 61507.70267409498 0.8269080961739462 0.8983875956592741 0.8264242831766684 0.9620885383274849 0.9879948910724007 1.0868751170003468 0.9534216092335885 0.9738209010173124 0.9503474609721821 1.0 15.908479471527627 -5.874540465906504 4.581758667236974 0.992109283314007 0.8557454091522697 0.7100551944708682 0.040430255475375376 0.12039324473369113 4.273097706077515 0.011943082505440305 0.01827271093004231 1.3349331997737923e-06 5.874540465906504 -0.13636387416173734 LGPGRPLPTFPTSECTS(ph)DVEPDTR ddPTM_PC-9_Lapatinib_30min_R1 1 LGPGRPLPTFPTSECTSDVEPDTR 24 1 H0YHZ9;Q8TDD1;Q8TDD1-2 H0YHZ9 DDX54 ATP-dependent RNA helicase DDX54 1 LGPGRPLPTFPT(0.001)S(0.004)ECT(0.216)S(0.771)DVEPDT(0.007)R 58.79600000000001 0.0025184 5164700.0 14601.0 20657.0 24616.0 18180.0 24673.0 21523.0 19531.0 14725.0 28934.0 17705.0 True False 14392.787062504538 20609.169985662287 22592.167500507876 19517.017846702154 23221.78264898437 20602.51146256351 20542.21961408306 15409.177256255365 25675.148231472558 20765.285659570414 0.6931177012665422 0.992481891341756 1.0879776888643706 0.9398867979312892 1.1182982516920874 0.992161234876541 0.989257742506203 0.7420643042853351 1.2364457032951657 1.0 14.341886098016271 -4.76275694095231 6.093666476775801 1.00589404685207 0.682360373114646 0.38199751087130085 0.12124184385547847 0.13475374550683103 20.063977678418087 0.028679610352970366 0.18217056853456792 1.7268040519069895e-05 4.76275694095231 -0.32353367373742403 LGPQNFIDETS(ph)DIENLLK ddPTM_PC-9_Lapatinib_30min_R1 2 LGPQNFIDETSDIENLLK 18 0 Q14692 Q14692 BMS1 Ribosome biogenesis protein BMS1 homolog 1 LGPQNFIDET(0.169)S(0.831)DIENLLK;LGPQNFIDET(0.091)S(0.909)DIENLLK 133.16 6.040800000000001e-06 0.0 5069.0 3653.6 1708.99 2848.3 1922.29 4571.4 2211.5 4486.1 3270.0 3484.6 True False 4996.715130459248 3645.140313676516 1568.4834390921744 3057.7734836502623 1809.2246815675492 4375.891878453879 2326.000649047396 4694.540583313223 2901.6981653734447 4086.9084670623597 1.2226148862225072 0.8919065212871324 0.38378237529248826 0.7481874155718902 0.4426878400014686 1.0707095384495455 0.5691345103012079 1.1486776914990768 0.7099983248362702 1.0 11.99679421688927 -6.787478326285503 24.999187832210765 0.8883356235283629 0.7273003425712018 0.08208255085113858 0.2681562702062929 650.0189739227726 624058.396296028 0.09509995858218709 0.08389679678265027 1.631254315876065e-07 6.787478326285503 -0.16103528095716113 LGPVT(ph)ET(ph)ETQLPWMLIGETLK ddPTM_PC-9_AZD4547_30min_R2 1 LGPVTETETQLPWMLIGETLK 21 0 O75691 O75691 UTP20 Small subunit processome component 20 homolog 2 LGPVT(0.963)ET(0.968)ET(0.069)QLPWMLIGETLK 49.638000000000005 0.044014 0.0 7820.9 8987.0 11422.0 12949.0 11094.0 11485.0 9947.0 12957.0 9221.8 10445.0 True False 10307.78351517425 11891.871999636429 11270.536816997777 9963.80811005569 9553.78959637927 10766.841134417005 10832.263730107676 10954.793372239668 9709.245521322164 10079.323729210573 1.022666181988141 1.179828361418035 1.1181838305614678 0.988539348248126 0.9478601792193391 1.0682106680643622 1.0747014404066644 1.0868579744583382 0.9632834287467226 1.0 13.299111224216237 -5.749028566496376 24.992374865731616 1.0235828916368617 1.1141863860166592 0.33110457826230344 0.0569766960466045 268.2717119696874 540229.5273692237 0.015990968822643302 0.027446781674133724 1.7822615321522166e-06 5.749028566496376 0.09060349437979753 LGQEATVGK ddPTM_PC-9_Lapatinib_30min_R1 2 LGQEATVGK 9 0 P53396;P53396-2;K7ESG8 P53396 ACLY ATP-citrate synthase 0 ; 99.815 0.009587100000000001 0.0 52255.0 59941.0 50917.0 49880.0 50529.0 54151.0 54271.0 52025.0 48540.0 45920.0 False True 51509.834117606595 59802.210297264035 46730.80080530384 53548.34159480217 47556.98356383622 51835.0879621464 57080.88682995754 54442.271426600055 43072.914051139785 53857.210815446095 0.9564148112704292 1.1103844664772897 0.8676795566973844 0.9942650349699257 0.8830198007617025 0.9624539997024919 1.0598559777920564 1.0108631806641233 0.7997613207029762 1.0 15.716851896301042 -5.258490530350266 24.94340636276863 0.9515769515516987 1.0333996268868053 0.150562033786658 0.08134172093980781 480.24867417613126 4062225.723772486 0.020558138515161316 0.04974776346585602 5.5145422653046005e-06 5.258490530350266 0.08182267533510656 LGQSDPAPLQHQMDIYQK ddPTM_PC-9_Lapatinib_30min_R1 1 LGQSDPAPLQHQMDIYQK 18 0 P29401;P29401-2;A0A0B4J1R6;E9PFF2 P29401 TKT Transketolase 0 127.61 3.6113000000000005e-05 5993200.0 78139.0 81933.0 90611.0 98774.0 98522.0 76797.0 92431.0 95592.0 76136.0 95760.0 False True 77024.72353106219 81743.28917244864 83161.31334857504 106038.16946040458 92727.12966170465 73512.5713325507 97216.62491164362 100033.55329575282 67560.76193237698 112311.98840782074 0.6858103451198327 0.7278233635720808 0.7404491232637119 0.944139365384263 0.8256209419514442 0.6545389532737693 0.8655943705549606 0.8906756501587063 0.6015454172804268 1.0 16.77715240656886 -11.94384037770417 2.3886127922475633 3.247227444200942 0.7781598376203414 0.3003620606164493 0.10443439905926016 10512251.419442622 1014458.4755693407 128906220.54151706 0.025958732207235245 1.1380454906639111e-12 11.94384037770417 -2.4690676065806008 LGQTPVT(ph)EAVSGR ddPTM_PC-9_Lapatinib_30min_R1 1 LGQTPVTEAVSGR 13 0 H0YCR5;Q9BQC3-2;Q9BQC3-3;Q9BQC3 H0YCR5 DPH2 Diphthamide biosynthesis protein 2 1 LGQT(0.052)PVT(0.933)EAVS(0.015)GR 85.163 0.020118 3640700.0 19930.0 27793.0 33195.0 25099.0 34509.0 24923.0 25586.0 22610.0 26523.0 19961.0 True False 19645.79454528563 27728.647016096846 30465.835236405554 26944.864187809548 32479.24846730439 23857.101388350628 26910.717886740524 23660.54314186308 23535.700440428103 23411.232253639384 0.8391610630504766 1.1844163825159737 1.301334116305198 1.1509374600997708 1.3873361348698483 1.0190450946742426 1.149478916581041 1.0106491997312503 1.0053166012553385 1.0 14.514913252462739 -7.617830637838361 1.5017456289446898 0.9961869036145992 1.1700834756628 0.167127660719263 0.1403707560925657 0.7123473924434393 3.0664653818963137 0.10372831691198818 0.04542169042109551 2.4108454046770045e-08 7.617830637838361 0.17389657204820086 LGRGS(ph)VSDCSDGTSELEEPLGEDPR ddPTM_PC-9_AZD4547_30min_R2 2 LGRGSVSDCSDGTSELEEPLGEDPR 25 1 P50548;P50548-2 P50548 ERF ETS domain-containing transcription factor ERF 1 LGRGS(0.796)VS(0.201)DCS(0.002)DGT(0.001)S(0.001)ELEEPLGEDPR;LGRGS(0.961)VS(0.037)DCS(0.002)DGTSELEEPLGEDPR 105.25 3.1869e-07 8737500.0 4583.0 4127.0 8329.8 11112.3 8078.599999999999 8008.8 5946.2 9613.3 6028.1 9504.2 True False 6040.298667678092 5460.9720421163365 8219.34140940537 8550.530918323564 6957.025836786514 7508.00846994505 6475.400280684255 8127.785376657537 6346.733059389943 9171.460850853331 0.6585972252300559 0.5954309930471149 0.8961867191136323 0.9322975976643901 0.7585515491939563 0.8186273257925415 0.7060380441008774 0.8862040092447554 0.692008957198943 1.0 13.16293583248722 -14.522878744628642 0.027271560994664525 2.0712029827193295 1.6568054932588705e-13 0.2744885934303678 0.10715739055300655 2786.4863670418763 5.709668138387236 325.42110698332124 142.72384859028472 3.000000004501755e-15 14.522878744628642 -2.071202982719164 LGRGS(ph)VSDCSDGTSELEEPLGEDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGRGSVSDCSDGTSELEEPLGEDPR 25 1 P50548;P50548-2 P50548 ERF ETS domain-containing transcription factor ERF 1 LGRGS(0.899)VS(0.081)DCS(0.02)DGTSELEEPLGEDPR 66.89399999999999 0.00035003 2466500.0 1586.3 1373.3 1004.1 3372.0 4678.0 6487.4 5456.5 5461.3 3524.5 3430.8 True False 1854.829259146863 1509.6321481764824 1028.0415520704553 3183.0777721715017 3761.3794813039835 6147.1893235849975 4939.620818361009 5317.94666172566 3576.039144801089 4052.7768818021423 0.4576687326350122 0.37249327860980014 0.253663495932033 0.7854066150209797 0.9280993232549768 1.5167845412826022 1.218823775012385 1.3121735582347027 0.8823676331303334 1.0 11.98469503730369 -6.124126126233496 2.0176033726672653 1.199941042007123 0.36402020633661675 0.7841115137306269 0.1835429223448682 0.1391826411192407 1.1179656119909858 0.06019907659298777 0.08668320055595083 7.514046421078781e-07 6.124126126233496 -0.8359208356705063 down LGRGS(ph)VSDCSDGTSELEEPLGEDPR ddPTM_PC-9_Lapatinib_30min_R1 2 LGRGSVSDCSDGTSELEEPLGEDPR 25 1 P50548;P50548-2 P50548 ERF ETS domain-containing transcription factor ERF 1 LGRGS(0.616)VS(0.254)DCS(0.084)DGT(0.033)S(0.013)ELEEPLGEDPR;LGRGS(0.858)VS(0.111)DCS(0.031)DGTSELEEPLGEDPR 102.92 4.6256e-07 5576000.0 3468.1000000000004 2948.4300000000003 4486.3 5086.2 9367.599999999999 10697.400000000001 12880.0 9674.5 17125.7 7483.0 True False 3418.644258028352 2941.603091485999 4117.4537316188025 5460.256115065817 8816.616185410207 10239.897138857361 13546.863377675987 10124.012588498648 15196.823324384093 8776.426579529258 0.38952576279760986 0.33517093373141144 0.4691492254060024 0.6221502641863027 1.0045792676001746 1.1667501626164802 1.5435511543244291 1.153546092678835 1.731550214278578 1.0 13.099417934516088 -6.35076235745735 1.235093559959365 1.3747592235151616 0.36022314870402194 0.8255653769103725 0.19080683717911243 0.16390864922187137 0.5145564153308065 0.07429757336214632 0.09861665645567404 4.45900174741093e-07 6.35076235745735 -1.0145360748111396 down LGS(ph)AEQSSPDLSFLVVK ddPTM_PC-9_AZD4547_30min_R2 2 LGSAEQSSPDLSFLVVK 17 0 Q96LW4;Q96LW4-2;A0A5S6SZ32 Q96LW4 PRIMPOL DNA-directed primase/polymerase protein 1 LGS(1)AEQSSPDLSFLVVK;LGS(0.999)AEQSSPDLSFLVVK 120.08 9.032200000000001e-05 6018700.0 16942.0 15143.8 20185.0 28116.8 25044.1 19158.8 20711.5 26643.3 19101.4 17484.2 True False 22329.20358450845 20038.73719685035 19917.333711355306 21634.90616022967 21567.159007633138 17960.797207319854 22554.783376508014 22526.190187126147 20111.061007719014 16872.08347977629 1.323440795635781 1.1876859915297222 1.1804904672993826 1.2822901324642173 1.278274792409876 1.0645275213845729 1.3368107977620718 1.335116093642326 1.1919725878445968 1.0 14.042350517984856 -8.548484434906134 21.98995400844143 0.9999999972302721 1.244471196341156 0.45983838746475714 0.08077751629185628 1320.3455688177728 1133901.4275170758 0.07858809329762388 0.020291358432670183 2.828235473057785e-09 8.548484434906134 0.244471199110884 LGS(ph)AEQSSPDLSFLVVK ddPTM_PC-9_Lapatinib_30min_R1 2 LGSAEQSSPDLSFLVVK 17 0 Q96LW4;Q96LW4-2;A0A5S6SZ32 Q96LW4 PRIMPOL DNA-directed primase/polymerase protein 1 LGS(1)AEQSSPDLSFLVVK;LGS(0.998)AEQSS(0.001)PDLSFLVVK 109.67 0.00044298 15798100.0 35498.0 28130.0 31718.0 26058.0 33172.0 26066.0 33873.0 28327.0 30496.0 43171.0 True False 34991.792010464065 28064.866713302035 29110.268475020686 27974.39224693977 31220.888178661266 24951.217942813768 35626.77819813808 29643.175832797657 27061.21934288334 50633.04982825841 0.691086002702825 0.5542796021273634 0.5749262304711928 0.552492736302193 0.6166108556478228 0.492785207042544 0.7036269456210932 0.5854511220110968 0.5344576207570341 1.0 15.627791765625881 -10.82922941123974 3.7011498225560833 1.0011108967121505 0.5881565195738268 0.794081769851073 0.06270463847765266 86858029.14361967 148140218.52261317 1089103.6723210537 0.014939724696713374 1.481735168224044e-11 10.82922941123974 -0.4129543771383237 LGS(ph)ALLIR ddPTM_PC-9_AZD4547_30min_R2 4 LGSALLIR 8 0 Q14993 Q14993 COL19A1 Collagen alpha-1(XIX) chain 1 LGS(1)ALLIR;LGS(1)ALLIR;LGS(1)ALLIR;LGS(1)ALLIR 136.99 0.0033176000000000004 89527000.0 93947.0 92135.0 112043.0 149044.0 133229.0 123811.0 111222.0 139912.0 115080.0 112430.0 True False 123820.19178100684 121915.8369518751 110557.2366124044 114684.20850684532 114732.45304993817 116069.07859758862 121120.54253443606 118291.81525791463 121162.89385952374 108493.8599210284 1.1412645090803695 1.1237118583541632 1.0190183729556486 1.0570571329135383 1.0575018082447318 1.069821634902419 1.11638154106231 1.090308846454703 1.1167718979462709 1.0 16.72725387183339 LGS(ph)ALLIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LGSALLIR 8 0 Q14993 Q14993 COL19A1 Collagen alpha-1(XIX) chain 1 LGS(1)ALLIR;LGS(1)ALLIR;LGS(1)ALLIR;LGS(1)ALLIR;LGS(1)ALLIR;LGS(1)ALLIR 117.01 0.0035650999999999994 83644100.0 84661.2 94403.1 97078.6 94519.6 110979.3 83235.5 100755.70000000001 72347.9 70218.5 69474.6 True False 98992.66902507999 103774.81587964726 99393.32199664053 89223.97324867766 89233.70283657081 78870.48385227655 91211.39068790186 70448.84428393656 71245.31272214933 82069.79501936889 1.2062010024725567 1.2644702701542738 1.211082859085772 1.0871718788577498 1.087290431461553 0.9610171907175193 1.1113880650777246 0.8584016113030412 0.8681063807377011 1.0 16.324563729521493 -6.308473381937174 0.6574934695055547 0.9212881677243597 1.2683259606471065 0.7384837473695636 0.06874135539034044 0.43024637695041446 0.3996949085144099 0.04649274051622607 0.08263188748638953 4.915035037001808e-07 6.308473381937174 0.3470377929227467 LGS(ph)ALLIR ddPTM_PC-9_Lapatinib_30min_R1 3 LGSALLIR 8 0 Q14993 Q14993 COL19A1 Collagen alpha-1(XIX) chain 1 LGS(1)ALLIR;LGS(1)ALLIR;LGS(1)ALLIR 131.62 0.0034216 49506000.0 99194.0 105519.0 108061.0 77728.0 103209.0 95301.0 85135.0 104398.0 100196.0 77143.0 True False 97779.47537004805 105274.6772385682 99176.64170752259 83444.37641300674 97138.44953670111 91225.19838748152 89542.87373124578 109248.71220363643 88910.87136934492 90477.06476341363 1.0807100741577915 1.1635509785142621 1.0961522897195801 0.922271037761929 1.0736251202523666 1.0082687654161215 0.9896748304710079 1.2074740984282408 0.9826896087073105 1.0 16.465264506048314 -5.537201323011121 24.91801404737615 1.032672167790854 1.1240608415585176 0.2303133103094479 0.0733962209909844 313.9381825843356 546178.3977108126 0.01968391085501576 0.03411180992921334 2.90267676792874e-06 5.537201323011121 0.09138867376766369 LGS(ph)FGSITR ddPTM_PC-9_AZD4547_30min_R2 7 LGSFGSITR 9 0 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 1 LGS(0.873)FGS(0.121)IT(0.006)R;LGS(0.999)FGS(0.001)ITR;LGS(0.999)FGS(0.001)ITR;LGS(0.999)FGSITR;LGS(0.862)FGS(0.126)IT(0.012)R;LGS(1)FGSITR;LGS(0.999)FGS(0.001)ITR 150.15 0.00023091 3096974640.0 611508.5 458258.8 611323.8 696651.5 661520.5 627435.2 559944.7 564132.8 496810.8 561220.5 True False 805955.48283304 606381.9953607422 603217.2469801252 536049.259833382 569679.7972500091 588201.5777571758 609778.6935433832 476959.0382421094 523071.20462864987 541572.3411172268 1.4881769648176804 1.1196694316216695 1.1138258016200184 0.9898017663301434 1.0518997260362275 1.086099737929297 1.1259413512245684 0.880693126347951 0.9658381067792157 1.0 19.046794534708738 -1.8683311817156123 0.9902082202550574 1.0179004754460765 199.99999996424316 0.8073528977840382 0.06792673703316882 313.139592333921 0.9805506098207163 0.02298927448420332 140610.78527927375 0.013541563739639443 1.8683311817156123 198.98209948879708 LGS(ph)FGSITR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 LGSFGSITR 9 0 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 1 LGS(0.981)FGS(0.015)IT(0.004)R;LGS(0.659)FGS(0.335)IT(0.007)R;LGS(0.902)FGS(0.081)IT(0.017)R;LGS(0.875)FGS(0.125)ITR;LGS(0.992)FGS(0.007)ITR;LGS(0.997)FGS(0.003)ITR;LGS(0.999)FGS(0.001)ITR 139.15 0.00084761 2128823200.0 223184.5 240673.40000000002 212250.4 274662.4 401141.9 416479.5 510640.7 491408.7 413516.9 289743.2 True False 260965.22775519305 264565.8645969105 217311.25450012484 259273.95619551474 322541.0243162229 394638.581849743 462269.1161774841 478509.7423155566 419563.8023653846 342271.34855409124 0.7624512798328812 0.7729711111215011 0.6349092771514347 0.757509961879091 0.9423547301834695 1.1529991730738625 1.3505924995776528 1.3980420632255603 1.2258221558357472 1.0 18.384781004210907 -6.641406428973113 1.9223797565089313 1.2755260890424471 0.7256145121478927 0.8261242710261594 0.10705562502908798 0.12209496061329887 0.9247973963872884 0.04100925003227039 0.040924188998361685 2.2834608553159623e-07 6.641406428973113 -0.5499115768945544 LGS(ph)FGSITR ddPTM_PC-9_Lapatinib_30min_R1 6 LGSFGSITR 9 0 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 1 LGS(0.997)FGS(0.003)ITR;LGS(1)FGSITR;LGS(1)FGSITR;LGS(0.924)FGS(0.074)IT(0.002)R;LGS(1)FGSITR;LGS(0.997)FGS(0.003)ITR 144.77 0.00053041 2415566200.0 260188.8 235440.7 253277.1 285545.7 417335.3 439550.0 483289.0 430691.0 462553.0 459811.0 True False 256478.45999921762 234895.55152458354 232453.6345158791 306545.68333053077 392788.45816676883 420751.47114109545 508311.3396687616 450702.4761747963 410455.4102409738 539288.7186903554 0.4755865478181464 0.43556548354102326 0.43103745073767713 0.5684259149254349 0.7283454011807301 0.7801970568990879 0.9425588224859934 0.8357350349721985 0.7611051298045897 1.0 19.040698329053484 -6.3255993437644715 1.351576824010419 0.8690190431959871 0.43804964031469906 0.8924643807449146 0.06459360351944193 0.1287666699498999 0.4771142178191231 0.025465827195215406 0.03386446252397948 4.724987416432778e-07 6.3255993437644715 -0.43096940288128804 LGS(ph)LSAR ddPTM_PC-9_AZD4547_30min_R2 4 LGSLSAR 7 0 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79;H0Y4T4;Q00G26 H0Y2V6 CEP170;PLIN5 Centrosomal protein of 170 kDa;Perilipin-5 1 LGS(0.997)LS(0.003)AR;LGS(0.998)LS(0.002)AR;LGS(0.998)LS(0.002)AR;LGS(0.995)LS(0.005)AR 122.19 0.0052951 54609000.0 134535.0 155971.0 174165.0 206082.0 195544.0 178922.0 154911.0 178246.0 144301.0 164485.0 True False 177314.33149816154 206385.57557085733 171855.4583026106 158572.97883516073 168396.09093513497 167733.97905547786 168697.77889762825 150702.17638560108 151928.45626366977 158726.43021533714 1.117106528872394 1.3002596687323158 1.082714819891444 0.9990332335958906 1.0609202935306958 1.0567488907040912 1.0628209723406707 0.9494460133775459 0.9571717580843665 1.0 17.27618285192159 -5.474061415700306 5.249943819237745 1.017454346456387 1.2077955837340375 0.6583351746997308 0.055947852307009445 0.11843294813611406 7.460916422584524 0.015034880819141928 0.031169151653064536 3.3569013930677803e-06 5.474061415700306 0.1903412372776505 LGS(ph)LSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LGSLSAR 7 0 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79;H0Y4T4;Q00G26 H0Y2V6 CEP170;PLIN5 Centrosomal protein of 170 kDa;Perilipin-5 1 LGS(0.969)LS(0.031)AR;LGS(0.998)LS(0.002)AR;LGS(0.997)LS(0.003)AR;LGS(0.994)LS(0.006)AR;LGS(1)LSAR 134.48 0.00032236 14941500.0 81463.5 87446.0 80135.8 104779.0 156044.0 148606.0 191668.0 196111.0 175175.0 133689.0 True False 95253.66157253389 96127.06096951914 82046.5413887137 98908.57232810122 125468.298371227 140812.8397540884 173511.81948384852 190963.2940467798 177736.60297645937 157925.75741845835 0.6031546919869365 0.6086851349701604 0.5195260274821015 0.6262979133037914 0.7944764706036628 0.8916394770295413 1.0986923369573687 1.2091966324453418 1.1254440433393516 1.0 17.268886965896755 -6.783246487728944 1.3005205177833945 1.1347595581970875 0.5779799824617655 0.9349189775172567 0.06103605762163459 0.09664246687394004 0.3427077902424628 0.030150752843416423 0.026664797538796376 1.6472272275811798e-07 6.783246487728944 -0.556779575735322 LGS(ph)LSAR ddPTM_PC-9_Lapatinib_30min_R1 4 LGSLSAR 7 0 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79;H0Y4T4;Q00G26 H0Y2V6 CEP170;PLIN5 Centrosomal protein of 170 kDa;Perilipin-5 1 LGS(0.997)LS(0.003)AR;LGS(0.998)LS(0.002)AR;LGS(0.999)LS(0.001)AR;LGS(0.986)LS(0.014)AR 131.22 0.0043473 44052700.0 74378.0 61731.0 69981.0 66249.0 105677.0 150756.0 189857.0 156513.0 138834.0 150812.0 True False 73317.35608074523 61588.065662241366 64227.4323144719 71121.17246018555 99461.2866289758 144308.5173094004 199686.86648256434 163785.165358798 123197.05293316738 176879.65325564175 0.4145041825403211 0.3481919176606988 0.36311373938326796 0.4020879233486233 0.5623105020746832 0.8158570793941645 1.128941982908343 0.9259695071997994 0.6965021169230378 1.0 17.432408576532758 -6.674754224235898 2.233810774971696 0.9363284598065345 0.37951464665732343 0.8603666428484784 0.1025557497404168 0.10987926955680208 1.1224954712599473 0.04044106050464335 0.039434911186719754 2.114685443233304e-07 6.674754224235898 -0.5568138131492111 down LGS(ph)LSER ddPTM_PC-9_AZD4547_30min_R2 1 LGSLSER 7 0 O60664-3;O60664;O60664-4;O60664-2 O60664-3 PLIN3 Perilipin-3 1 LGS(0.985)LS(0.015)ER 72.87899999999999 0.037712999999999997 5557000.0 30571.0 28738.0 26729.0 49462.0 41879.0 35947.0 31171.0 37589.0 38043.0 33288.0 True False 40291.94208369779 38026.99649778029 26374.55599558164 38059.300080282235 36064.82373415968 33699.22840739123 33945.158613771644 31780.483759289742 40053.875313676224 32122.597252078638 1.2543176931650668 1.1838082767519547 0.8210592620705648 1.1848139109554547 1.1227244002452492 1.0490816836179262 1.0567376712222443 0.9893497561824096 1.2469065000989095 1.0 14.971300925306524 -5.014851097673615 24.721169359707883 1.060653149300583 1.2366904656884965 0.2638730397287371 0.10981220503016553 670.0647877704137 1115405.3773734397 0.02673442629406051 0.07699006232404554 9.663821562494856e-06 5.014851097673615 0.17603731638791342 LGS(ph)LSER ddPTM_PC-9_Lapatinib_30min_R1 2 LGSLSER 7 0 O60664-3;O60664;O60664-4;O60664-2 O60664-3 PLIN3 Perilipin-3 1 LGS(0.997)LS(0.003)ER;LGS(0.973)LS(0.027)ER 100.02 0.011655 9783800.0 47712.0 40956.0 46534.0 43329.0 49823.0 52176.0 49147.0 46109.0 57922.0 50776.0 True False 47031.61813069081 40861.16889832916 42708.154146434565 46515.559201306816 46892.50909578681 49944.55410819651 51691.591181882126 48251.39246918023 51398.21441429988 59552.563945232876 0.7897496768391555 0.6861361827495264 0.7171505526732793 0.7810840729558604 0.7874137734676074 0.8386633723130325 0.8679994236590713 0.8102319912464946 0.8630730737566213 1.0 15.861876002020773 -8.82934111026727 0.1345209408070786 1.1661599274279475 0.6047494280071836 0.8163196572594976 0.03550999741714348 4.6084555425957054 0.3382966426464987 0.7921453422995232 0.478219606861827 1.4813541201058235e-09 8.82934111026727 -0.5614104994207639 LGS(ph)PDATR ddPTM_PC-9_AZD4547_30min_R2 1 LGSPDATR 8 0 H0Y8W3;O43566-4;O43566-5;O43566 H0Y8W3 RGS14 Regulator of G-protein signaling 14 1 LGS(1)PDATR 96.665 0.0060501999999999995 19091000.0 74945.0 55648.0 79800.0 96471.0 73211.0 72432.0 68841.0 64388.0 56618.0 71990.0 True False 98775.95104716007 73635.127744049 78741.79985960636 74231.10141209232 63046.91636384732 67902.81558973365 74967.71563731188 54438.31408904596 59610.71189206209 69469.65201205063 1.4218575764569223 1.0599610853279615 1.1334704806920195 1.0685399920992225 0.9075461663880339 0.9774457424654267 1.0791433880265806 0.7836272748221448 0.8580827766593916 1.0 16.08409525013876 -1.5228787452805628 0.45739221678074293 0.9165431845586403 11.773350824268253 0.6958712733306505 0.09194289940211008 52.689018411212366 0.6240675316972619 0.057562619931218396 536.7156869024226 0.029999999999984442 1.5228787452805628 10.856807639709611 LGS(ph)PDATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGSPDATR 8 0 H0Y8W3;O43566-4;O43566-5;O43566 H0Y8W3 RGS14 Regulator of G-protein signaling 14 1 LGS(0.999)PDAT(0.001)R 81.525 0.017759999999999998 13539000.0 58378.0 67133.0 53640.0 73735.0 63464.0 62874.0 70346.0 65673.0 64389.0 53504.0 True False 68260.24238194269 73797.52057345925 54918.98103083281 69603.86700209534 51028.68478013592 59576.77675664882 63682.317619064095 63949.15333629527 65330.567312979794 63203.85166256907 1.0800013066666971 1.1676111286294284 0.8689182634633204 1.101259894313 0.8073666942414588 0.9426130716639807 1.0075702025099584 1.01179202934823 1.033648513412834 1.0 15.947724858919681 -5.247452957435476 24.9940988412596 0.971075280168306 1.123806229515653 0.3574904870657434 0.08159302878782766 837.2909600330296 1496254.188520496 0.020300491449071065 0.053147096075493484 5.6564902459479815e-06 5.247452957435476 0.152730949347347 LGS(ph)PDTVSPR ddPTM_PC-9_AZD4547_30min_R2 1 LGSPDTVSPR 10 0 H0Y9Y2 H0Y9Y2 BOD1L1 1 LGS(0.695)PDT(0.099)VS(0.205)PR 94.465 0.0062919 4174200.0 26257.0 21062.0 18209.0 40457.0 29741.0 25725.0 27343.0 28016.0 26891.0 29771.0 True False 34606.179820472105 27869.879610141565 17967.53676245075 31130.263704419143 25611.975517028655 24116.411683315393 29776.47402959024 23686.770943634074 28312.40336093543 28728.72635158716 1.2045845470820964 0.9701049489303883 0.6254205822618414 1.0835935893377782 0.8915109985588932 0.8394528663810064 1.036470383865284 0.8244977745880985 0.9855084772796157 1.0 14.810206413945133 -4.802715378621499 4.42343844290258 0.9056423105559146 1.219086494467753 0.3303213511518174 0.12434874889430385 0.2020134336972787 7.783764781484695 0.029607253933139413 0.18211897608107677 1.57501473574612e-05 4.802715378621499 0.3134441839118385 LGS(ph)PDTVSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGSPDTVSPR 10 0 H0Y9Y2 H0Y9Y2 BOD1L1 1 LGS(0.594)PDT(0.406)VSPR 103.31 0.0094615 0.0 19643.0 19266.0 22933.0 19533.0 20803.0 21320.0 25242.0 22745.0 21533.0 14645.0 True False 22968.171933065507 21178.601155441727 23479.80969388683 18438.629336840422 16726.80148558502 20201.941668285013 22850.895023745736 22147.96785031955 21847.87938856628 17300.022570243797 1.3276382640431337 1.2241950014486758 1.3572126625009338 1.0658153341692767 0.966865876484767 1.167740769485038 1.3208592607878729 1.2802276852756405 1.2628815540474982 1.0 14.078486299605528 -11.728265183675406 2.3014644248314533 0.36206823110760866 1.2148007602526558 0.23950906400037553 0.11697246057074347 5984613.829998149 2279172.111240903 19561246.83833855 0.033069483715320265 1.8695402355903496e-12 11.728265183675406 0.8527325291450472 LGS(ph)PDTVSPR ddPTM_PC-9_Lapatinib_30min_R1 1 LGSPDTVSPR 10 0 H0Y9Y2 H0Y9Y2 BOD1L1 1 LGS(0.856)PDT(0.143)VS(0.001)PR 107.11 0.0069842 0.0 20096.0 18783.0 16791.0 17415.0 21403.0 19613.0 16475.0 16688.0 18962.0 18717.0 True False 19809.42735484496 18739.50911752409 15410.508795134372 18695.757194736976 20144.117619917004 18774.197710136057 17327.994887205892 17463.38540253919 16826.29988128784 21952.208511165183 0.9023888118031325 0.8536502879877862 0.7020026612491579 0.8516572346344136 0.9176351258540315 0.8552304749012953 0.789350870022606 0.7955183822920177 0.7664969049801874 1.0 14.422078469552702 -4.885085425805086 4.896645351121044 0.8270933624596959 0.899436349462466 0.05490180247880827 0.07834715199948111 0.5410703582119186 19.50259132489574 0.0193120224941927 0.08991345848886115 1.302910470514173e-05 4.885085425805086 0.07234298700277009 LGS(ph)PDYGNSALLSLPGYRPTTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGSPDYGNSALLSLPGYRPTTR 22 1 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 LGS(0.958)PDY(0.011)GNS(0.031)ALLSLPGYRPTTR 58.332 0.0046328 31755000.0 28801.0 23605.0 20735.0 26056.0 21935.0 32460.0 29786.0 31441.0 22066.0 28386.0 True False 33676.44045432062 25948.3483999897 21229.401037925396 24596.16679469178 17636.994211715024 30757.74045743581 26964.45444803464 30615.707064493166 22388.673505229337 33532.15709654764 1.0043028355544663 0.7738347498873329 0.6331057371823867 0.733509828308186 0.5259725510927798 0.9172610151168152 0.8041371859972233 0.9130252782826566 0.6676776993727731 1.0 15.03325767307162 LGS(ph)PGAPQQEDAMDDKELIEYFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGSPGAPQQEDAMDDKELIEYFK 23 1 H0YGG4 H0YGG4 EIF2B1 1 LGS(0.866)PGAPQQEDAMDDKELIEY(0.134)FK 58.47 0.010398000000000001 6893400.0 21078.0 20886.0 16928.0 26726.0 25519.0 18382.0 30625.0 21538.0 21095.0 17808.0 True False 24646.089090523597 22959.42404923471 17331.627719797507 25228.628866861065 20518.735139674296 17418.015560338434 27723.978294200664 20972.650321397352 21403.47446718085 21036.449431949575 1.1715897766042116 1.0914115579963115 0.8238855979885423 1.1992817014331574 0.9753896543259344 0.8279921769442915 1.3179019769417104 0.9969672110895612 1.0174470999214273 1.0 14.360603604180758 -5.0021602518992 23.977115225798652 1.023647550472947 1.1515454377730985 0.10184521015631609 0.14130073537248972 124.87683105367442 1386296.5976877522 0.03436146647347677 0.12452428188851282 9.9503818684608e-06 5.0021602518992 0.1278978873001515 LGS(ph)PLAVDEALR ddPTM_PC-9_AZD4547_30min_R2 4 LGSPLAVDEALR 12 0 Q7RTP6 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 LGS(1)PLAVDEALR;LGS(1)PLAVDEALR;LGS(1)PLAVDEALR;LGS(1)PLAVDEALR 180.61 0.00019099999999999998 16878300.0 40879.3 41401.4 43741.8 55002.1 59419.9 58192.0 53161.5 55762.3 45404.7 48779.3 True False 53878.06705773797 54783.59290149633 43161.755151615616 42322.215618973976 51170.4725471333 54553.2450408354 57892.77051252836 47145.51782517871 47804.69974646778 47071.55155426339 1.1445993445877418 1.1638365656662628 0.916939291917314 0.8991039007963345 1.087078518925486 1.158942997193267 1.2298887247383472 1.0015713582508545 1.0155751864554374 1.0 15.5225677869159 LGS(ph)PLAVDEALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LGSPLAVDEALR 12 0 Q7RTP6 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 LGS(1)PLAVDEALR;LGS(1)PLAVDEALR;LGS(1)PLAVDEALR;LGS(1)PLAVDEALR 151.7 5.9204e-05 14770800.0 33166.6 38180.200000000004 32643.0 43716.0 47711.5 36684.3 52467.0 41825.9 41318.2 38553.2 True False 38781.05030979028 41970.47793184866 33421.33291926688 41266.734249184265 38362.7740748685 34760.510728980684 47496.945931814735 40728.01444320426 41922.400508645274 45542.589973036724 0.8515337035673732 0.9215654611803388 0.7338478760003291 0.9061130312003783 0.8423494161746401 0.7632528310216982 1.0429127100574447 0.8942841078497531 0.9205098026586813 1.0 15.474928718345174 -7.258010230376313 24.99868914271927 0.9556169962093399 0.8390846718293513 0.4760932168336828 0.06547626428560602 290.7698166168362 2119736.2501884494 0.025263413591484138 0.018770086568323872 5.5206443452552515e-08 7.258010230376313 -0.11653232437998862 LGS(ph)PLAVDEALR ddPTM_PC-9_Lapatinib_30min_R1 4 LGSPLAVDEALR 12 0 Q7RTP6 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 LGS(1)PLAVDEALR;LGS(1)PLAVDEALR;LGS(1)PLAVDEALR;LGS(1)PLAVDEALR 186.16 5.9204e-05 16923000.0 31694.8 38468.0 30028.199999999997 34086.1 50388.9 46302.1 55629.7 47079.0 44877.1 47470.8 True False 31242.82633988555 38378.929709466895 27559.397308204047 36592.905501896275 47425.123970389 44321.867118466835 58509.93366778738 49266.46221033929 39822.568421186756 55676.064529135045 0.5611536412300894 0.6893254764690375 0.4949954265137101 0.657246624943244 0.8518045298545058 0.7960668106358953 1.0508992358317528 0.8848768789065248 0.7152547285440367 1.0 15.764769617227476 -6.247958546827857 2.5302126796074798 0.8889118705908508 0.5887392951725017 0.6681349239854368 0.09874901863210411 0.18064464891006404 2.2869690825083144 0.03246988048606467 0.041515676484586296 5.649909003128932e-07 6.247958546827857 -0.3001725754183491 LGS(ph)PVDNLEDMDRDDLTDDSVFTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGSPVDNLEDMDRDDLTDDSVFTR 24 1 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 LGS(0.998)PVDNLEDMDRDDLT(0.002)DDSVFTR;LGS(1)PVDNLEDMDRDDLTDDSVFTR 53.196999999999996 0.020622 14829400.0 11399.2 12393.5 8433.6 13503.9 15497.6 10108.9 14644.0 12669.2 10241.599999999999 9962.900000000001 True False 13328.859415537358 13623.844774211922 8634.689008606108 12747.320263234496 12460.95653045245 9578.771488298606 13256.814306621209 12336.646924126986 10391.364024796367 11769.094903727 1.1325305407569122 1.1575949455465404 0.7336748559884331 1.083118146935642 1.0587863070512205 0.8138919404299502 1.1264089902464023 1.0482239309855728 0.8829365477803788 1.0 13.522715754461627 LGS(ph)PVDNLEDMDRDDLTDDSVFTR ddPTM_PC-9_Lapatinib_30min_R1 1 LGSPVDNLEDMDRDDLTDDSVFTR 24 1 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 LGS(1)PVDNLEDMDRDDLTDDSVFTR 84.641 1.0843e-05 1925500.0 1060.2 990.19 770.26 1223.4 1235.5 1109.0 665.9 1168.5 1195.9 733.31 True False 1045.0813535831314 987.897275892092 706.932196089584 1313.3729171427624 1162.8303190864583 1061.5706552052657 700.3770437262762 1222.792775818974 1061.2051486147109 860.0616564258445 1.2151237597617974 1.1486354129510825 0.8219552526354679 1.5270683297296872 1.3520313461232867 1.2342959917743939 0.814333528873768 1.421750134636312 1.2338710145790683 1.0 9.748296277765434 -11.919524230858933 1.7903480076476752 9.499751924259238e-05 1.194919581572256 0.06803163944144175 0.21818006274079257 2792190.887128442 259749.1772659206 11274108.08570847 0.060429757754826494 1.203582235714485e-12 11.919524230858933 1.1948245840530134 LGS(ph)QHSPGR ddPTM_PC-9_Lapatinib_30min_R1 3 LGSQHSPGR 9 0 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 LGS(0.633)QHS(0.367)PGR;LGS(0.851)QHS(0.149)PGR;LGS(0.996)QHS(0.004)PGR 76.165 0.017022 20071500.0 129892.0 134089.0 112533.0 160869.0 72567.0 51649.5 50729.5 60999.4 93730.0 107406.0 True False 128039.71626072482 133778.52515890345 103280.97112994215 172699.84290325237 68298.75173221134 49440.57128586508 53356.025288650184 63833.654813257985 83173.1403793435 125970.98399050083 1.0164222919016017 1.0619788853041854 0.8198790535583204 1.3709493839968359 0.5421784411667498 0.39247586801094825 0.42355805756565046 0.5067330014511241 0.6602563363767595 1.0 16.942731937735203 -6.2880893365797155 24.295826999593565 0.5449185030493182 1.049253321254769 0.5642685691487603 0.20424874680883703 350.5161852742972 319552.12648879515 0.060660443331403566 0.06880523063926186 5.151226703339926e-07 6.2880893365797155 0.5043348182054508 LGS(ph)SGLGSASSIQAAVR ddPTM_PC-9_AZD4547_30min_R2 4 LGSSGLGSASSIQAAVR 17 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 LGS(0.959)S(0.041)GLGSASSIQAAVR;LGS(0.452)S(0.061)GLGS(0.031)AS(0.02)S(0.436)IQAAVR;LGS(0.948)S(0.052)GLGS(0.001)ASSIQAAVR;LGS(0.5)S(0.5)GLGSASSIQAAVR 241.66 3.7026999999999993e-38 37295200.0 43914.2 49646.2 65054.3 94240.7 85819.6 71429.4 65946.7 78316.5 59697.8 61791.9 True False 57878.00212789644 65693.36326564489 64191.63747627545 72514.96261930084 73905.02989412563 66962.90832622792 71815.82854431416 66214.48445913463 62853.30383252581 59628.584388990574 0.9706418946712854 1.1017092546938625 1.076524591922517 1.216110752290298 1.2394228481427938 1.1230001351263255 1.2043859380564763 1.1104487074048337 1.0540800939109771 1.0 15.863716466450297 -4.551231777310273 1.4305060283705033 1.142836247020547 0.8178835857484388 0.28754676188704265 0.07207946937143189 2.529000150439885 3.1314423118720214 0.02071441726095265 1.378042894068183 2.8104005559121215e-05 4.551231777310273 -0.3249526612721083 LGS(ph)SGLGSASSIQAAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGSSGLGSASSIQAAVR 17 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 LGS(0.973)S(0.027)GLGSASSIQAAVR;LGS(0.5)S(0.5)GLGSASSIQAAVR 175.8 5.2224e-06 15761000.0 22786.0 22979.0 20160.0 39615.0 35164.0 32192.0 36391.0 42593.0 31509.0 29342.0 True False 26643.219755985887 25260.203257079593 20640.690857225767 37395.49998356288 28273.86662688611 30503.794849222842 32943.781031975734 41474.97888101385 31969.759515828482 34661.4723288558 0.7686695909280608 0.7287689056431218 0.5954937707606355 1.0788780011641625 0.8157145304917706 0.8800490227251058 0.95044378725222 1.1965729120654167 0.9223428021900137 1.0 15.081045317268092 -6.253078095390283 0.6362820476195178 1.0373425930486293 0.6874387686491483 0.4391976373640816 0.1251735268083279 0.8484870735891167 0.7226079969982527 0.08549684780017706 0.16591373772391074 5.583697789394549e-07 6.253078095390283 -0.349903824399481 LGS(ph)SGLGSASSIQAAVR ddPTM_PC-9_Lapatinib_30min_R1 2 LGSSGLGSASSIQAAVR 17 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 LGS(0.5)S(0.5)GLGSASSIQAAVR;LGS(0.5)S(0.5)GLGSASSIQAAVR 204.81 3.2133e-17 15101400.0 39959.0 41239.0 27093.0 26346.0 33618.0 31599.0 27727.0 31201.0 34622.0 22100.0 True False 39389.177332416875 41143.513629216606 24865.518122004374 28283.572727679595 31640.655335530988 30247.584430866726 29162.568390747067 32650.712364850508 30722.505774177207 25919.955553601045 1.5196467930264086 1.5873296365857603 0.9593194737770228 1.0911890905519 1.220706388562274 1.1669612769326083 1.1251010184195909 1.2596747049712576 1.185283891040814 1.0 14.66177562390415 -5.2486790578490226 24.986371948838137 1.138869286337937 1.5534882860805375 0.7833078264399272 0.08972794318096049 346.0112254916415 677532.1844972905 0.023385624047692538 0.06101761957422158 5.640543360880059e-06 5.2486790578490226 0.4146189997426004 LGS(ph)SSNLQFK ddPTM_PC-9_AZD4547_30min_R2 1 LGSSSNLQFK 10 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;A0A0J9YYG8;Q8TDM6-5 Q8TDM6-4 DLG5 Disks large homolog 5 1 LGS(0.961)S(0.032)S(0.007)NLQFK 98.902 0.004580399999999999 47699000.0 131810.0 129770.0 141820.0 195210.0 165550.0 188480.0 171790.0 168090.0 167370.0 170350.0 True False 173722.83818168216 171715.61470933762 139939.37413645815 150207.3504644353 142566.24010100844 176694.31580452068 187078.9771986725 142115.55282393805 176216.836507373 164386.09835050485 1.056797624159614 1.0445872031295782 0.8512847226173513 0.9137472813799769 0.8672645773064581 1.0748738340864579 1.1380462160479154 0.8645229386789056 1.0719692131851841 1.0 17.32672877413284 -6.775088564509025 24.99495652906138 1.0281753526108708 0.9450368435846671 0.17390131443072954 0.09053397900142676 466.6029760424943 854457.3934929272 0.033485244510733855 0.02968601253285897 1.6784616990265737e-07 6.775088564509025 -0.08313850902620368 LGS(ph)SSNLQFK ddPTM_PC-9_Lapatinib_30min_R1 1 LGSSSNLQFK 10 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;A0A0J9YYG8;Q8TDM6-5 Q8TDM6-4 DLG5 Disks large homolog 5 1 LGS(0.926)S(0.031)S(0.043)NLQFK 82.505 0.014823 41940000.0 26178.0 28800.0 37454.0 21265.0 27884.0 29483.0 20192.0 21813.0 25370.0 23869.0 True False 25804.69691954273 28733.315369466734 34374.67669662097 22828.89903796047 26243.917942053245 28222.080818229817 21237.442959785218 22826.51161227153 22512.56344205637 27994.724846556706 0.921769978486381 1.0263832035127458 1.2278983588884598 0.8154714562507435 0.9374593994368619 1.0081213861868363 0.7586230290238906 0.8153861749807176 0.804171627528083 1.0 14.772867379766137 -6.454288395234248 1.0253892858401563 0.8440970534710792 1.0343113458974518 0.2322895405795754 0.11774651981825761 0.7002500135510644 1.5744227390632781 0.0584827597224527 0.07314898832913852 3.5132706270847344e-07 6.454288395234248 0.19021429242637256 LGS(ph)TGSQPNSEAESVPENVPKPPLLPPK ddPTM_PC-9_Lapatinib_30min_R1 1 LGSTGSQPNSEAESVPENVPKPPLLPPK 28 1 A0A0J9YVR0;Q8IZ21-3;Q8IZ21;Q8IZ21-2 A0A0J9YVR0;Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 LGS(0.589)T(0.205)GS(0.205)QPNS(0.001)EAES(0.001)VPENVPKPPLLPPK 93.125 1.9158e-08 5585300.0 9307.5 18759.0 18133.0 12932.0 38084.0 64186.0 80253.0 75783.0 64375.0 68554.0 True False 9174.77334321354 18715.56468804953 16642.17473540418 13883.062419887363 35843.97399602482 61440.91440487392 84408.10765905523 79304.15483944304 57124.40960119738 80403.46755753702 0.11410917491398039 0.23277061620080752 0.20698329613079158 0.17266745877536427 0.44580134520162 0.7641575204565223 1.0498068083774181 0.9863275459194928 0.7104719651589522 1.0 16.29497010135399 -6.684447148842831 2.035437043255195 0.936176077768813 0.18559995429943585 0.9332410649903948 0.09216814238228631 0.07561741585034884 0.6434288183115411 0.03614118267309005 0.03500179248801844 2.0680110317342373e-07 6.684447148842831 -0.7505761234693771 down LGS(ph)VDSFER ddPTM_PC-9_AZD4547_30min_R2 4 LGSVDSFER 9 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 LGS(0.999)VDS(0.001)FER;LGS(0.893)VDS(0.107)FER;LGS(0.555)VDS(0.445)FER;LGS(0.923)VDS(0.077)FER 157.78 0.00010686 89583400.0 65413.1 76157.1 57557.4 76045.0 83664.0 77269.0 79125.1 80366.7 70826.8 75522.1 True False 86213.10512299661 100773.39324173922 56794.1512686629 58514.00013353814 72048.69774576135 72437.35721508648 86167.08061437031 67947.87315804389 74570.56005222203 72878.09426613823 1.1829769424013918 1.3827665810487877 0.7793034634146779 0.8029024458276187 0.988619398891688 0.9939524070231275 1.1823454150667414 0.9323497525869705 1.0232232442838476 1.0 16.153197613267636 -5.251885457531106 24.999583816937598 0.9645806340236954 1.2828717784154524 0.5482337768831423 0.11619804142773726 531.9986818088843 1392064.892840487 0.03167295873963376 0.08148279632832968 5.599052535518903e-06 5.251885457531106 0.318291144391757 LGS(ph)VDSFER ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LGSVDSFER 9 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 LGS(0.985)VDS(0.015)FER;LGS(0.937)VDS(0.063)FER;LGS(0.628)VDS(0.372)FER;LGS(0.866)VDS(0.134)FER;LGS(0.838)VDS(0.162)FER 147.3 0.00038937 107492400.0 133306.1 142462.5 95556.8 145609.9 239091.7 218823.1 306900.0 242241.0 226648.0 226370.0 True False 155872.18981451014 156605.23549813734 97835.2365131821 137451.84937666528 192243.39771912963 207347.6314199481 277828.21023641364 235882.4304255559 229962.2982241098 267409.0890560654 0.5828978751796643 0.5856391645136012 0.3658635421052192 0.5140133787593394 0.7189112322162825 0.7753948534504572 1.0389632275295015 0.8821032645457328 0.8599644052334195 1.0 18.028688976940863 -6.647164810530051 1.7286914555196125 0.9314143524666955 0.5067300472607147 0.8427431646264181 0.08244520488001762 0.13911487010075688 0.855742354004597 0.034599569406243445 0.03442479407785929 2.2533839126051143e-07 6.647164810530051 -0.42468430520598077 LGS(ph)VDSFER ddPTM_PC-9_Lapatinib_30min_R1 4 LGSVDSFER 9 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 LGS(0.882)VDS(0.118)FER;LGS(0.965)VDS(0.035)FER;LGS(0.921)VDS(0.079)FER;LGS(0.983)VDS(0.017)FER 147.3 0.00038937 62570300.0 58626.1 61293.7 53073.1 54637.100000000006 106522.0 126722.0 129460.0 123781.0 112354.0 98381.0 True False 57790.08106328995 61151.778203523674 48709.63458609053 58655.29459802258 100256.58539030973 121302.39546341001 136162.8053473551 129532.31714475705 99699.50937992909 115386.02476555777 0.5008412516221812 0.5299756043053944 0.42214501006563965 0.5083396773326654 0.8688797936666234 1.05127458641437 1.1800632323022806 1.1225997031091228 0.8640518605480979 1.0 16.816108973789717 -6.398200224289716 2.5506446002318337 1.0586566794480976 0.4812330853576098 0.9098935741373979 0.08223554003206188 0.08052466136072697 1.0224752435403057 0.029219754546294528 0.03379247022384202 3.9976040434537267e-07 6.398200224289716 -0.5774235940904878 LGS(ph)VEAPK ddPTM_PC-9_AZD4547_30min_R2 1 LGSVEAPK 8 0 P46087-2;P46087;P46087-4;P46087-3;F5H359;F5GWB7;F5H709;F5H5X6 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 LGS(1)VEAPK 82.645 0.016176 2193200.0 20552.0 24355.0 15727.0 27593.0 22455.0 22811.0 22096.0 17097.0 17238.0 24823.0 True False 27087.108491843814 32227.27746201681 15518.449704160741 21231.860157600335 19337.510851514027 21384.62456396921 24062.50119437611 14455.051499975429 18149.165487925522 23953.95432553316 1.1307990373418615 1.3453844415017897 0.6478450068521343 0.8863613860601182 0.8072784388213372 0.8927388051823564 1.0045314801626406 0.6034515764508829 0.7576688692513638 1.0 14.547976215674945 -5.255885566049384 24.999792162431312 0.8212138688257027 1.238091764726217 0.6030440631016133 0.1340383148841045 288.24520194584375 1297489.672153638 0.03389215457057976 0.08447568317008478 5.547718727102067e-06 5.255885566049384 0.4168778959005144 LGS(ph)VEAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGSVEAPK 8 0 P46087-2;P46087;P46087-4;P46087-3;F5H359;F5GWB7;F5H709;F5H5X6 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 LGS(1)VEAPK;LGS(1)VEAPK 88.49600000000001 0.027214999999999996 11555000.0 70540.0 68293.0 47594.0 68633.0 91127.0 77657.0 120893.0 113446.0 84639.0 70810.0 True False 82481.02877149341 75072.67770728635 48728.821461250154 64787.71552118819 73271.31851064318 73584.53021266457 109441.139850475 110468.16270597278 85876.68525374374 83647.29246834856 0.9860573646505479 0.8974908271620773 0.5825510906965546 0.7745345199989985 0.8759556507865265 0.8797000840225443 1.3083644027317036 1.320642419451568 1.0266523006257346 1.0 16.352031222793308 -7.145514953890539 4.975400741747273 1.1891421325613452 0.8175236812366812 0.5795243314443377 0.13788428800484903 0.15898656476678782 5.862134394374509 0.0559202760595745 0.042980233898906275 7.152947641889168e-08 7.145514953890539 -0.371618451324664 LGS(ph)VEAPK ddPTM_PC-9_Lapatinib_30min_R1 1 LGSVEAPK 8 0 P46087-2;P46087;P46087-4;P46087-3;F5H359;F5GWB7;F5H709;F5H5X6 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 LGS(1)VEAPK 76.943 0.024242 27463000.0 45798.0 59649.0 69028.0 60028.0 81465.0 78350.0 114170.0 99273.0 75201.0 83167.0 True False 45144.91212167543 59510.88640532362 63352.78429578558 64442.65936753782 76673.38886635232 74999.15314277062 120081.16396189979 103885.58599390434 66731.0714783635 97542.30513693814 0.4628239209468874 0.6101033425627701 0.6494903335208818 0.6606636912780333 0.7860526646229217 0.7688884637028053 1.2310675228898855 1.06503107393311 0.6841244051458573 1.0 16.573740446349447 -6.5427021750051875 1.25069217896277 0.9910899167971265 0.576355273984 0.5929809494898779 0.1429130489247603 0.32256324206286957 1.054424321900497 0.06606467224370374 0.07303829501554064 2.86614280339954e-07 6.5427021750051875 -0.41473464281312655 LGS(ph)YSGPTSVSR ddPTM_PC-9_AZD4547_30min_R2 1 LGSYSGPTSVSR 12 0 V9GYZ0;Q9BZ23-3;Q9BZ23-4;Q9BZ23;A0A2R8YFI4 V9GYZ0 PANK2 Pantothenate kinase 2, mitochondrial 1 LGS(0.942)YS(0.048)GPT(0.008)S(0.002)VSR 101.72 0.0026327 97386000.0 52447.0 115970.0 49620.0 162050.0 139740.0 99673.0 43804.0 114400.0 127320.0 95892.0 True False 69124.05503463083 153455.0345830463 48962.00637886796 124691.87614754228 120339.51308797885 93440.43155339525 47702.47114040783 96722.10865047599 134049.87527106822 92534.8502672531 0.7470056398750444 1.6583485480318767 0.5291196369525546 1.3475125943081483 1.3004777415257294 1.0097863808449108 0.5155081680322243 1.0452506095933534 1.448642050902056 1.0 16.497709192083256 -6.979746173165444 24.37071499533832 0.9713390731141569 1.1296319082552437 0.020314576916508176 0.36126219525631087 698.3271506370481 840268.0728504277 0.12547768007379762 0.11064708411758008 1.0477407294675896e-07 6.979746173165444 0.15829283514108683 LGS(ph)YSGPTSVSR ddPTM_PC-9_Lapatinib_30min_R1 2 LGSYSGPTSVSR 12 0 V9GYZ0;Q9BZ23-3;Q9BZ23-4;Q9BZ23;A0A2R8YFI4 V9GYZ0 PANK2 Pantothenate kinase 2, mitochondrial 1 LGS(0.991)YS(0.009)GPTSVSR;LGS(0.966)YS(0.033)GPTSVSR 126.32 0.00026707 150747000.0 67426.0 77490.0 65662.0 75223.0 77178.0 84599.0 89518.0 85341.0 98448.0 111795.0 True False 66464.49287558589 77310.57666597153 60263.5238226498 80755.15035657183 72638.54177778603 80980.8979799011 94152.80402506211 89306.25441263783 87359.7495366009 131118.61679252586 0.5069035542127116 0.5896231866776256 0.45961073489668625 0.6158938549844061 0.5539910620985641 0.6176155603291663 0.7180734996163344 0.6811104067239409 0.6662650329421462 1.0 17.00051301466796 -14.522878745280336 0.11787580262838811 2.3586870466929333 0.39352575811195367 0.8861076067821798 0.04764794376946734 47.131105845184464 0.3608150935807132 15.121540613648719 0.47962525134785905 3.0000000000000132e-15 14.522878745280336 -1.9651612885809797 LGSAPAASPALAS(ph)PEGPK ddPTM_PC-9_AZD4547_30min_R2 3 LGSAPAASPALASPEGPK 18 0 Q6ZUT6;Q6ZUT6-4;Q6ZUT6-2 Q6ZUT6 C15orf52 Uncharacterized protein C15orf52 1 LGSAPAASPALAS(1)PEGPK;LGSAPAASPALAS(1)PEGPK;LGSAPAASPALAS(1)PEGPK 156.08 1.4597000000000001e-05 58425700.0 169318.0 191935.0 171473.0 155016.0 143729.0 201721.0 203032.0 193161.0 207045.0 164794.0 True False 223157.60196681588 253974.23525650578 169199.15598153198 119279.4561733256 123774.70929313134 189107.35398134388 221101.45467489908 163312.40584820433 217988.97600925513 159024.6122193899 1.403289710016386 1.597075016954757 1.063980937416815 0.7500691528728144 0.7783368094139548 1.1891703513192782 1.3903599674864677 1.026963081808362 1.3707876596392397 1.0 17.278890542958635 -5.269379510137946 24.323940547923012 1.0658536649950772 1.5001823684951112 0.4116351822291675 0.20506364230865148 381.1054518094969 1167489.9438469918 0.058683142485798784 0.12595188363667764 5.377996185631727e-06 5.269379510137946 0.43432870350003405 LGSAPAASPALAS(ph)PEGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LGSAPAASPALASPEGPK 18 0 Q6ZUT6;Q6ZUT6-4;Q6ZUT6-2 Q6ZUT6 C15orf52 Uncharacterized protein C15orf52 1 LGSAPAASPALAS(1)PEGPK;LGSAPAASPALAS(1)PEGPK;LGSAPAAS(0.001)PALAS(0.999)PEGPK;LGSAPAASPALAS(1)PEGPK 237.39 2.0404e-43 43934700.0 178458.0 300638.0 203927.0 196030.0 203256.0 143099.0 217641.0 143980.0 159957.0 144422.0 True False 208667.41469383528 330483.353792675 208789.39307745468 185047.07463783532 163429.4458854048 135594.6365286077 197024.46889561252 140200.67755942006 162296.06851608644 170604.56535607722 1.2231056903917852 1.9371307743313133 1.223820667645558 1.0846548816065644 0.9579429808592937 0.7947890271611514 1.1548604721356255 0.8217873728455056 0.9512996805059132 1.0 17.380296727942053 -5.58946737182041 2.8512961870071285 0.9550487534602483 1.5843304985783588 0.6124524511881028 0.1923955708192378 0.14949773810679226 2.443617866100872 0.050746636224227246 0.10357974642253058 2.5735501058207334e-06 5.58946737182041 0.6292817451181105 LGSAPAASPALAS(ph)PEGPK ddPTM_PC-9_Lapatinib_30min_R1 3 LGSAPAASPALASPEGPK 18 0 Q6ZUT6;Q6ZUT6-4;Q6ZUT6-2 Q6ZUT6 C15orf52 Uncharacterized protein C15orf52 1 LGSAPAASPALAS(1)PEGPK;LGSAPAAS(0.002)PALAS(0.998)PEGPK;LGSAPAAS(0.122)PALAS(0.878)PEGPK 169.58 8.232900000000001e-08 36275500.0 110833.0 130337.0 115461.0 108586.0 150378.0 141273.0 148086.0 136181.0 124896.0 120071.0 True False 109252.50109571696 130035.21268438126 105968.24227234897 116571.77667227713 141533.06169452332 135231.0831134476 155753.1684896372 142508.46641318264 110828.89726681389 140825.1123654491 0.7758026907317536 0.9233808551626257 0.7524811483718572 0.8277769121871303 1.005027152595036 0.9602767634405667 1.1060042195134128 1.011953507577293 0.7869966897608904 1.0 17.103545097152292 -6.255231977984559 22.571734232344667 0.9844504801578993 0.8224418698417383 0.45117479298573204 0.08547288639318125 124.24891165625475 451798.0657149712 0.025700655141349622 0.032244958691186106 5.556074008298155e-07 6.255231977984559 -0.16200861031616098 LGSFGS(ph)ITR ddPTM_PC-9_AZD4547_30min_R2 1 LGSFGSITR 9 0 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 1 LGS(0.01)FGS(0.987)IT(0.003)R 70.41199999999999 0.037743 5659300.0 14839.0 13146.0 14035.0 21252.0 20752.0 20561.0 18937.0 18859.0 22042.0 16221.0 True False 19557.493329625842 17395.187415958644 13848.88672969391 16352.679740126929 17870.943005594254 19275.31741965591 20622.356314170007 15944.774886707411 23207.09512036513 15653.107727288132 1.2494319767269715 1.111292895891436 0.8847372017731076 1.0446922122448075 1.141686578598048 1.2314051468548424 1.3174608310028406 1.0186331790786065 1.4825870699086865 1.0 13.93416149406492 -6.518468332565811 3.546933745011478 1.217068748824816 1.0631645022188834 0.14840396547312007 0.15384175660167537 0.4186607076000745 11.287889829512775 0.050475410316209064 0.053758750017808415 3.0306212734277507e-07 6.518468332565811 -0.1539042466059326 LGSFGS(ph)ITR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGSFGSITR 9 0 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 1 LGS(0.313)FGS(0.687)ITR;LGS(0.117)FGS(0.874)IT(0.009)R 93.556 0.0061653 4331200.0 6387.700000000001 7449.8 6600.2 8408.4 13305.300000000001 11588.7 11947.8 13455.3 11691.8 7538.0 True False 7469.011447174185 8189.366909987005 6757.573799397888 7937.304608400604 10698.221977895233 10980.96817125959 10816.017889418797 13102.112632068789 11862.770456287517 8904.579729224832 0.838783151400272 0.919680339669429 0.758887449479455 0.8913732988824131 1.2014291862403867 1.2331820821616153 1.2146578747473757 1.4713903441245693 1.3322100331533786 1.0 13.120331806503154 -6.295312445968724 2.8380836046477422 1.2748202580969548 0.8412851378595549 0.7291103989340691 0.11658316583834079 0.136324445060948 2.192488548687275 0.038038321330071914 0.0465604245200929 5.066260933842944e-07 6.295312445968724 -0.4335351202373998 LGSFGS(ph)ITR ddPTM_PC-9_Lapatinib_30min_R1 2 LGSFGSITR 9 0 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 1 LGS(0.021)FGS(0.963)IT(0.016)R;LGS(0.019)FGS(0.751)IT(0.23)R 79.036 0.020731 14997100.0 38591.0 37537.0 43162.0 31380.0 24518.3 27573.3 20728.1 16213.6 27382.0 19016.9 True False 38040.68526327733 37450.08538276639 39613.38697013818 33687.78988061131 23076.18179883246 26394.05423550169 21801.299594627762 16966.94304665684 24297.95081475709 22303.94582657356 1.7055585392408266 1.6790789250459568 1.7760708028147043 1.5103959695093372 1.03462328945127 1.183380485261718 0.9774637978475123 0.7607148608853748 1.089401445093532 1.0 14.445011341751288 -6.182751304101874 2.103702398398849 0.984836108546894 1.723370208932863 0.9077885699380135 0.10450152274316364 0.09171985083663066 0.7972078144029571 0.03635718584436541 0.049770020453742965 6.565211112058186e-07 6.182751304101874 0.7385341003859691 LGSPDTVS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 LGSPDTVSPR 10 0 H0Y9Y2 H0Y9Y2 BOD1L1 1 LGSPDT(0.001)VS(0.999)PR;LGSPDT(0.002)VS(0.998)PR 126.03 0.00035989 18099100.0 82362.0 84161.0 112529.0 148581.0 142650.0 118515.0 108096.0 133243.0 108983.0 123151.0 True False 108551.40276397615 111364.39739194413 111036.7919348575 114327.9460035667 122845.5098182351 111104.2383147959 117716.3345903007 112653.35596954 114743.61888679588 118839.52097424702 0.9134284779513682 0.9370990094791549 0.9343423048542883 0.962036408985038 1.033709230827817 0.9349098465221231 0.9905487133006055 0.9479452209669578 0.9655341753831309 1.0 16.858655169429348 -5.805964830833442 3.791905824783566 0.976251812024963 0.9282418355164512 0.4165170430464039 0.02655921085104104 0.2262703404361165 6.739479768904775 0.007489096725317049 0.012161093100143985 1.5632742314604547e-06 5.805964830833442 -0.0480099765085118 LGSPDTVS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGSPDTVSPR 10 0 H0Y9Y2 H0Y9Y2 BOD1L1 1 LGSPDT(0.002)VS(0.998)PR;LGSPDT(0.094)VS(0.906)PR 80.737 0.017245 13259900.0 57777.0 64615.0 80974.0 78012.0 97855.0 87321.0 81234.0 92577.0 77250.0 60707.0 True False 67557.50495223365 71029.55017434162 82904.72725560526 73641.24055831638 78681.01520799496 82741.73304016487 73538.92743677046 90146.9518434395 78379.6351073582 71712.69854365235 0.9420577711367341 0.9904738158905722 1.1560675994522809 1.0268926153084323 1.0971699128028338 1.1537947214439157 1.025465906739048 1.2570570299842503 1.0929673084279155 1.0 16.1299409866752 -5.107993474989229 4.552186639262968 1.1064378053517672 0.9519169712957247 0.36329644013497786 0.0722317861294339 0.20870045207251575 6.816205039442152 0.017874577150507873 0.053400555175802465 7.798418270849653e-06 5.107993474989229 -0.15452083405604244 LGSPDTVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 LGSPDTVSPR 10 0 H0Y9Y2 H0Y9Y2 BOD1L1 1 LGSPDT(0.001)VS(0.999)PR;LGSPDT(0.002)VS(0.998)PR 115.91 0.0010842 19968500.0 132137.0 104177.0 119535.0 105073.0 129513.0 117456.0 94387.0 102305.0 105941.0 90529.0 True False 130252.70214904202 103935.78455711574 109707.2937184439 112800.41893325263 121895.2999723548 112432.68068330911 99273.89702086206 107058.46378276432 94008.8089718128 106176.81702769008 1.2267527488140197 0.9788933918598266 1.0332509185110823 1.0623827506887418 1.148040630569717 1.0589192992476648 0.9349865610962157 1.0083035711538075 0.8853986360063519 1.0 16.69610927249728 -7.178293676726993 5.0792387784137825 0.958060437725098 1.0809029964327166 0.44436624900947597 0.07005416959735658 0.2244296323575753 9.982121659074942 0.02691988968161708 0.02058203589262436 6.6329438866755e-08 7.178293676726993 0.12284255870761862 LGSQHS(ph)PGR ddPTM_PC-9_AZD4547_30min_R2 6 LGSQHSPGR 9 0 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 LGS(0.006)QHS(0.994)PGR;LGSQHS(1)PGR;LGS(0.018)QHS(0.982)PGR;LGS(0.007)QHS(0.993)PGR;LGS(0.001)QHS(0.999)PGR;LGS(0.068)QHS(0.932)PGR 112.64 0.0012209000000000002 208299800.0 76653.6 74237.20000000001 254060.0 554117.0 427328.0 328637.0 186212.0 388220.0 228690.0 332683.0 True False 101027.85030607237 98232.92311243003 250690.99840014495 426373.88667230925 368000.8834182042 308087.27643808385 202784.50725955665 328229.5194081101 240778.08652011186 321035.86943082407 0.31469334091915724 0.3059873754499479 0.7808815844927358 1.3281191520070412 1.1462921077032484 0.9596662110819665 0.6316568538558651 1.022407620650116 0.7500036894537545 1.0 18.29237497352556 -5.3557762046809945 3.794281986440851 0.9741453001491263 0.3049565410381735 0.6734027897446235 0.18241230731681657 0.13732331203230808 3.5917460265376198 0.05271775424388332 0.12245604498568274 4.407819433517924e-06 5.3557762046809945 -0.6691887591109528 LGSQHS(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 LGSQHSPGR 9 0 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 LGS(0.02)QHS(0.98)PGR;LGS(0.001)QHS(0.999)PGR;LGSQHS(1)PGR;LGS(0.242)QHS(0.758)PGR;LGSQHS(1)PGR;LGS(0.018)QHS(0.982)PGR;LGS(0.011)QHS(0.989)PGR 107.34 0.0014218 114654400.0 174868.8 180519.1 280486.0 310156.0 389927.0 342467.0 245194.0 278771.0 253423.0 184757.0 True False 204470.6340237669 198439.84323882966 287173.84998907853 292778.9648593198 313523.6034643903 324507.4276413024 221967.44926916703 271453.55663229007 257128.83194578724 218251.98156439295 0.9368557964887938 0.9092235580930205 1.3157903444022152 1.3414721953987778 1.4365212229328075 1.4868475663555885 1.0170237524449595 1.2437621628292093 1.1781282813687723 1.0 17.73563522694053 -5.258288239091735 24.717906017760395 1.2708665573304527 0.9230396314918451 0.42776274683718263 0.15119994975053797 206.0656198166457 1616377.5489373785 0.04011812328915595 0.09728886471594493 5.517111497906071e-06 5.258288239091735 -0.34782692583860764 LGSQHS(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 5 LGSQHSPGR 9 0 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 LGS(0.01)QHS(0.99)PGR;LGSQHS(1)PGR;LGSQHS(1)PGR;LGSQHS(1)PGR;LGSQHS(1)PGR 112.64 0.0012209000000000002 108676000.0 253009.0 161060.0 506807.0 218742.0 326426.0 375417.0 228944.0 263903.0 516710.0 174306.0 True False 249401.0452638314 160687.07546549663 465139.2847915938 234829.0163819212 307226.2644582082 359361.2900497703 240797.6000884044 276164.89680526766 458512.6786024813 204434.55985185486 1.219955400126876 0.7860073931821498 2.275247810980006 1.1486757256311844 1.502809821787677 1.7578304290144697 1.1778712966286147 1.3508718731578102 2.2428334961307237 1.0 17.641279580263543 -5.200830714442739 24.999998525124635 1.5466648417903983 1.0029810673187616 0.21521882238646484 0.4228164081709054 361.4354648825108 149083.92136051517 0.10150300191138002 0.2685516222884161 6.29751608672121e-06 5.200830714442739 -0.5436837744716367 LGSQPIRAS(ph)NPDLR ddPTM_PC-9_AZD4547_30min_R2 2 LGSQPIRASNPDLR 14 1 Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5;Q9UKE5-8;Q9UKE5-5;Q9UKE5-7;Q9UKE5-3 Q9UKE5-6 TNIK TRAF2 and NCK-interacting protein kinase 1 LGSQPIRAS(1)NPDLR;LGSQPIRAS(1)NPDLR 73.36 0.0097485 142386000.0 74613.0 81968.0 107466.0 148653.0 111870.0 121830.0 98458.0 129346.0 106242.0 113085.0 True False 98338.38195318909 108462.55302839645 106040.93062296309 114383.34751595558 96338.78151676124 114211.9508407509 107220.57126158077 109358.54777538903 111857.73522265822 109125.92857039503 0.9011458893543609 0.9939210089601148 0.971729927178197 1.0481775414370846 0.8828221008411851 1.046606909439263 0.9825398295915975 1.002131658424734 1.025033524919799 1.0 16.735634404472094 -4.761284040811916 23.70512469356859 0.9935279887037162 0.9011457956717558 0.2849351787570724 0.044457055316583706 2.4619060622530347 373286.7136326601 0.010376474842243771 0.05832160199499508 1.7326704118904746e-05 4.761284040811916 -0.09238219303196038 LGSQPIRAS(ph)NPDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LGSQPIRASNPDLR 14 1 Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5;Q9UKE5-8;Q9UKE5-5;Q9UKE5-7;Q9UKE5-3 Q9UKE5-6 TNIK TRAF2 and NCK-interacting protein kinase 1 LGSQPIRAS(1)NPDLR;LGSQPIRAS(1)NPDLR;LGSQPIRAS(1)NPDLR;LGSQPIRAS(1)NPDLR 99.669 0.0010136000000000001 121295000.0 205664.0 225550.0 293738.0 329453.0 356848.0 320825.0 312233.0 299548.0 285219.0 204236.0 True False 240478.85315084178 247941.11339197913 300741.82792756904 310994.8165110375 286926.19605480233 304000.37221986597 282656.02986883797 291685.1823973405 289389.7882936641 241262.37006871373 0.9967524279992408 1.0276824907314108 1.2465343345583275 1.2890315900588365 1.1892704028940906 1.2600405613742578 1.1715711397029505 1.2089957597376908 1.199481660613892 1.0 17.88024338895959 -5.220314279780703 6.929883081072579 1.207607662009781 1.0099262162163005 0.48419015184408976 0.07492776833866334 0.17086705514047262 23.158415520964063 0.01783415927447374 0.04716686347071117 6.02123697987374e-06 5.220314279780703 -0.19768144579348057 LGSQPIRAS(ph)NPDLR ddPTM_PC-9_Lapatinib_30min_R1 3 LGSQPIRASNPDLR 14 1 Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5;Q9UKE5-8;Q9UKE5-5;Q9UKE5-7;Q9UKE5-3 Q9UKE5-6 TNIK TRAF2 and NCK-interacting protein kinase 1 LGS(0.008)QPIRAS(0.992)NPDLR;LGSQPIRAS(1)NPDLR;LGSQPIRAS(1)NPDLR 104.81 0.00048669 89932500.0 210692.0 191808.0 191865.0 184872.0 187473.0 169182.0 153342.0 150895.0 182652.0 146448.0 True False 207687.49344381964 191363.8803606485 176090.6003203179 198468.10359491332 176446.20672609904 161946.4802425045 161281.29845183142 157906.13256928037 162079.80834917148 171761.34167030625 1.2091631994961543 1.1141266043902305 1.0252050817018046 1.1554876182550458 1.0272754335185932 0.9428575642670441 0.9389848547026889 0.9193345314708778 0.9436338047491597 1.0 17.390045840037807 -6.535379099267376 2.975396035081574 0.9430846223168005 1.1179147931003148 0.7528497444053346 0.04752339028066732 0.1326573155226124 2.4045942189077594 0.01666166653444996 0.017612615812108674 2.9148814788533676e-07 6.535379099267376 0.17483017078351437 LGSQPIRAS(ph)NPDLRR ddPTM_PC-9_AZD4547_30min_R2 1 LGSQPIRASNPDLRR 15 2 Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5;Q9UKE5-8;Q9UKE5-5;Q9UKE5-7;Q9UKE5-3 Q9UKE5-6 TNIK TRAF2 and NCK-interacting protein kinase 1 LGSQPIRAS(1)NPDLRR 50.102 0.03211 13205000.0 33560.0 24473.0 37135.0 63849.0 61830.0 42796.0 33176.0 44809.0 30390.0 45428.0 True False 44231.38190863557 32383.418654401055 36642.565636422034 49129.59950721647 53245.97176348752 40119.95935468092 36128.59972957198 37884.79865838446 31996.353357585365 43837.579547207075 1.0089832140710329 0.7387136559291223 0.8358710954139931 1.120718799136951 1.2146193360458895 0.9151955871896899 0.8241467732192289 0.8642082671920268 0.7298841242621452 1.0 15.419880522929038 -11.092991242080412 6.171182113666389 1.0001785184508492 0.9197204726918493 0.02675233017727041 0.1494663642390796 0.00040329703354720136 2.809383568721408e-05 0.15898267241282954 0.03847364967666396 8.072513089976175e-12 11.092991242080412 -0.08045804575899984 LGSQPIRAS(ph)NPDLRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGSQPIRASNPDLRR 15 2 Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5;Q9UKE5-8;Q9UKE5-5;Q9UKE5-7;Q9UKE5-3 Q9UKE5-6 TNIK TRAF2 and NCK-interacting protein kinase 1 LGS(0.002)QPIRAS(0.998)NPDLRR 62.081 0.014223 4127900.0 16435.0 12889.0 15473.0 22410.0 24096.0 26387.0 21199.0 26146.0 22361.0 17384.0 True False 19217.120893953655 14168.5347395665 15841.935001679263 21154.440354200273 19374.561774583315 25003.219268341305 19190.877252530936 25459.695203976913 22687.987322144167 20535.581588331712 0.9357962817509291 0.6899504978041158 0.7714383414726675 1.0301359259394045 0.9434630176528291 1.2175559363046284 0.9345183222585313 1.2397844733281416 1.1048134782330903 1.0 14.32583818602008 -5.980537898981246 1.7430588644319784 1.0933624820038124 0.7852818081177867 0.5304992096307198 0.1136157852094919 0.255858017182296 1.5695005684110923 0.03613394054789093 0.060840288912058546 1.0458324212565563e-06 5.980537898981246 -0.30808067388602567 LGSS(ph)GLGSASSIQAAVR ddPTM_PC-9_AZD4547_30min_R2 3 LGSSGLGSASSIQAAVR 17 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 LGS(0.149)S(0.849)GLGSASS(0.002)IQAAVR;LGS(0.062)S(0.917)GLGS(0.014)AS(0.003)S(0.003)IQAAVR;LGS(0.365)S(0.631)GLGS(0.002)AS(0.001)S(0.001)IQAAVR 104.78 0.00076574 15638500.0 30484.9 27303.2 34631.3 42693.0 39103.4 36479.6 29426.6 33730.6 34482.4 35248.4 True False 40178.46407468908 36128.42545682353 34172.06633431055 32850.78845027477 33674.567883816206 34198.524845196225 32045.510393122193 28518.310822078212 36305.06926678517 34014.36424477797 1.1812204921883098 1.0621520130975288 1.004636338001137 0.965791634789063 0.9900102098479194 1.0054142008679914 0.9421169880616527 0.8384196340361253 1.067345225256088 1.0 15.053856503806214 -3.078112178825197 0.7189870735900012 0.9612474320883138 3.6112153474200683 0.5716910404847614 0.05541347287854495 19.346978654386593 1.0330190920223445 0.0212204926674355 70.14840185681813 0.0008353872087663012 3.078112178825197 2.6499679153317546 LGSS(ph)GLGSASSIQAAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGSSGLGSASSIQAAVR 17 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 LGS(0.041)S(0.645)GLGS(0.294)AS(0.001)S(0.019)IQAAVR;LGS(0.084)S(0.439)GLGS(0.031)AS(0.006)S(0.439)IQAAVR 144.15 0.00011225 19917700.0 26400.6 34310.3 28368.9 35565.0 52814.0 37190.0 46495.0 36114.0 32964.6 30157.6 True False 30869.700144381673 37716.39983512675 29045.322165652386 33572.40835328572 42465.47582847124 35239.6909307467 42090.65700535051 35166.04576594593 33446.64491210382 35624.934152569745 0.8665195004200432 1.0587079171458944 0.8153087958355496 0.942385134229477 1.1920155598493383 0.9891861351891016 1.181494310279711 0.9871188986719652 0.9388549258466825 1.0 15.120599727107907 -6.027910162417532 24.695058357916203 1.0526459029793402 0.9198341930220726 0.29691088089098616 0.09649904024151472 758.4058860790121 671040.751172166 0.027840421386515397 0.03603481049427489 9.377559698241084e-07 6.027910162417532 -0.13281170995726765 LGSS(ph)GLGSASSIQAAVR ddPTM_PC-9_Lapatinib_30min_R1 1 LGSSGLGSASSIQAAVR 17 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 LGS(0.012)S(0.933)GLGS(0.025)AS(0.003)S(0.027)IQAAVR 112.57 0.00025125 5352400.0 15322.0 11623.0 12355.0 8356.1 11817.0 9119.0 13064.0 9674.8 14353.0 7552.3 True False 15103.505470289325 11596.087657614995 11339.21959167918 8970.635469132452 11121.94729311588 8729.001627427246 13740.389997357075 10124.326527593845 12736.413996209505 8857.70499219281 1.7051262695700036 1.3091526154727209 1.280153222722317 1.0127494059735767 1.2556240361266011 0.9854698971258352 1.5512359024677236 1.1429965816785992 1.4378909669531095 1.0 13.112717233410736 -4.655828220582096 2.048333792044737 1.212466674484983 1.970258419996457 0.4141286811441339 0.17697405764433932 1.0858604277190922 3.7724974687869204 0.0450199408132304 1.7330480587847896 2.2088782527272594e-05 4.655828220582096 0.757791745511474 LGSS(ph)SNLQFK ddPTM_PC-9_AZD4547_30min_R2 1 LGSSSNLQFK 10 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;A0A0J9YYG8;Q8TDM6-5 Q8TDM6-4 DLG5 Disks large homolog 5 1 LGS(0.081)S(0.727)S(0.192)NLQFK 114.76 0.0011805 53802000.0 97351.0 103170.0 137800.0 141970.0 147200.0 146100.0 139230.0 148810.0 133920.0 194790.0 True False 128306.59297340858 136517.68490068868 135972.68196307938 109241.00991463482 126763.82085695259 136964.34390407716 151621.20027575077 125814.8338136134 140998.7377969012 187970.46138946147 0.6825891261051193 0.7262720104614401 0.7233726031099834 0.5811605137697416 0.674381601874706 0.7286482295763309 0.8066224828889599 0.6693330052158247 0.7501111438182929 1.0 17.52014644189746 -12.26418823827449 0.28385815530449615 1.5207832410515745 0.6787559906705705 0.7447202811805848 0.05304652675360726 29.00842339292588 0.8728898440881108 9.210535719581378 0.06515447780750411 5.442666976677761e-13 12.26418823827449 -0.842027250381004 LGSS(ph)SNLQFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGSSSNLQFK 10 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;A0A0J9YYG8;Q8TDM6-5 Q8TDM6-4 DLG5 Disks large homolog 5 1 LGS(0.268)S(0.559)S(0.173)NLQFK 85.973 0.011563 42613000.0 107560.0 181230.0 136610.0 175630.0 223900.0 165390.0 206030.0 162120.0 193310.0 180750.0 True False 125767.7835931644 199221.316692656 139867.3004963099 165790.02050014262 180028.40227959838 156716.65724754508 186513.34687197255 157864.52178033878 196136.7930434102 213518.54418378716 0.5890251082121895 0.9330398792958013 0.6550592644352166 0.77646661152503 0.8431511322250212 0.7339721139754982 0.8735229419297195 0.7393480617049173 0.9185937164997925 1.0 17.704001848452002 -14.522878745251912 0.10080776983614574 1.72886995040601 0.6354499323914525 0.4041846705646309 0.09540128848708665 189.62333031454378 1.2934167596286372 28.550081017635605 1.4631962516864339 3.000000000196356e-15 14.522878745251912 -1.0934200180145575 LGSSDILNYS(ph)GNLMEPPFQNQK ddPTM_PC-9_AZD4547_30min_R2 2 LGSSDILNYSGNLMEPPFQNQK 22 0 O14530 O14530 TXNDC9 Thioredoxin domain-containing protein 9 1 LGS(0.006)S(0.005)DILNY(0.001)S(0.989)GNLMEPPFQNQK;LGS(0.011)S(0.01)DILNY(0.411)S(0.568)GNLMEPPFQNQK 95.444 0.00011376 9701500.0 33032.0 39334.0 49078.0 57764.0 48740.0 54124.0 38412.0 54247.0 37504.0 53147.0 True False 43535.48889171782 52047.9462817068 48427.193653004484 44447.40224490361 41973.29231364032 50739.617723916956 41830.59358609593 45864.37262204873 39486.38487406653 51286.3397066878 0.8488710471580162 1.0148500863850825 0.9442513138969346 0.8666518706365707 0.8184107611050072 0.9893398127864533 0.8156283685934632 0.8942804825681089 0.7699201210282015 1.0 15.646286989752458 -5.75782511985754 24.75894938427847 0.874181399379923 0.9438767650513732 0.09515464494466253 0.07811857862190569 158.30254438457723 1084403.785000808 0.020310737562717625 0.033483820987096 1.7465252958759878e-06 5.75782511985754 0.06969536567145018 LGSSDILNYS(ph)GNLMEPPFQNQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGSSDILNYSGNLMEPPFQNQK 22 0 O14530 O14530 TXNDC9 Thioredoxin domain-containing protein 9 1 LGS(0.001)S(0.001)DILNY(0.207)S(0.792)GNLMEPPFQNQK;LGS(0.003)S(0.003)DILNYS(0.994)GNLMEPPFQNQK 113.31 2.4821e-06 10092800.0 78784.0 76841.0 83753.0 92605.0 98210.0 82197.0 88202.0 81646.0 85080.0 68128.0 True False 92120.5751450712 84469.26665552265 85749.98915502147 87416.64207946096 78966.45550638378 77886.44462045132 79846.86803281927 79502.87901108753 86324.13404445372 80479.06709904858 1.1446526216773236 1.0495805890935985 1.0654943235050893 1.0862034716664153 0.9812049064783122 0.967785132556191 0.9921445527511987 0.9878702857382824 1.072628413276851 1.0 16.29632596129109 -6.256227024821452 24.919430382339844 0.9976349912880058 1.0823477140627267 0.5929287340763916 0.03488632007281698 308.56025263756123 1475179.2615879532 0.010500058185781704 0.013128090891754332 5.543358614767254e-07 6.256227024821452 0.08471272277472086 LGSSGLGS(ph)ASSIQAAVR ddPTM_PC-9_AZD4547_30min_R2 1 LGSSGLGSASSIQAAVR 17 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 LGS(0.001)S(0.113)GLGS(0.57)AS(0.014)S(0.302)IQAAVR 153.68 2.5701e-05 10724000.0 10972.0 13279.0 16263.0 29940.0 20948.0 20892.0 16243.0 27198.0 20823.0 17315.0 True False 14460.867768222564 17571.177065001903 16047.341993944565 23037.795568388883 18039.731788800524 19585.619937330426 17688.595533139534 22995.174047864075 21923.661269002954 16708.807120275833 0.8654638038567436 1.0516117002559446 0.9604121873231398 1.3787815852175909 1.0796540805662684 1.1721734410090612 1.0586390402265609 1.3762307436034646 1.3121021214254722 1.0 14.028321119346357 -5.728971955490554 24.925381964617596 1.2008100270404054 0.9684071631017723 0.41238354715887227 0.12978929037549847 188.97257703719671 145073.65283305605 0.0348904632227242 0.0604263940918622 1.8665002159508445e-06 5.728971955490554 -0.23240286393863308 LGSSGLGS(ph)ASSIQAAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGSSGLGSASSIQAAVR 17 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 LGS(0.023)S(0.341)GLGS(0.485)AS(0.046)S(0.105)IQAAVR 105.2 0.0051722 0.0 9452.9 12655.0 9641.1 14498.0 12740.0 9288.8 12873.0 13386.0 10867.0 10985.0 True False 11053.089266714602 13911.30476601863 9870.980388075364 13685.724063150188 10243.688454855228 8801.67897600215 11653.576247550855 13034.631683639373 11025.90931665581 12976.493542787854 0.8517778111836497 1.072038815427942 0.7606816398842592 1.0546550204817475 0.7894034255924646 0.6782786849914471 0.8980527913126226 1.0044802658483833 0.8496832584472599 1.0 13.663612976149437 -10.678108729699773 6.8876785039827 1.0000001726612433 0.8863160524427075 0.07506279366393409 0.1216231663966839 3.2324097633328403e-07 3.957946436633685e-08 0.118029429739346 0.028626298005033583 2.098414460098399e-11 10.678108729699773 -0.1136841202185358 LGSSGLGS(ph)ASSIQAAVR ddPTM_PC-9_Lapatinib_30min_R1 1 LGSSGLGSASSIQAAVR 17 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 LGSSGLGS(0.531)AS(0.148)S(0.321)IQAAVR 92.633 0.002013 18700000.0 31618.0 28999.0 29691.0 23885.0 29441.0 29932.0 30046.0 26656.0 36753.0 20817.0 True False 31167.121521968933 28931.854597193247 27249.920590574402 25641.58257802425 27709.33826323305 28651.87813489994 31601.634863792893 27894.535072512273 32613.49011375238 24415.19071309108 1.2765463062820788 1.1849940038223987 1.1161051703750722 1.050230689546717 1.1349220486889622 1.1735266978495158 1.2943431503424032 1.1425073594676292 1.3357868262018322 1.0 14.575491426816496 -7.005667803794723 23.76858776847935 1.2091635045918292 1.1474086444820442 0.024482479962573356 0.10007498361499584 373.9393992114662 1568166.1121329872 0.03507167862280715 0.0299595644826967 9.870341893057778e-08 7.005667803794723 -0.06175486010978504 LGSSGLGSASS(ph)IQAAVR ddPTM_PC-9_AZD4547_30min_R2 1 LGSSGLGSASSIQAAVR 17 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 LGSS(0.001)GLGS(0.097)AS(0.184)S(0.719)IQAAVR 115.58 0.00015134 18611000.0 17526.0 15660.0 25972.0 29991.0 28659.0 25028.0 24532.0 27892.0 22919.0 24886.0 True False 23098.903436553857 20721.788752009164 25627.59431019666 23077.03830633103 24680.192540349148 23462.995203499228 26715.30047521883 23581.93229439755 24130.45154993416 24014.748714708872 0.9618632162661745 0.8628776006853325 1.0671606276063146 0.9609527286952829 1.0277097975725515 0.9770243895630814 1.1124538837608529 0.9819770581215274 1.0048179906689767 1.0 14.551633092145593 -5.26098216740485 24.999635349626686 1.0163002602869273 0.9123704082036894 0.4295625811369681 0.04800325240377459 34.43170499003544 1882547.6894468546 0.011768007509563996 0.027464570641193963 5.482994782206692e-06 5.26098216740485 -0.1039298520832379 LGSSGLGSASS(ph)IQAAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGSSGLGSASSIQAAVR 17 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 LGSS(0.001)GLGS(0.225)AS(0.319)S(0.455)IQAAVR 120.59 8.340000000000001e-05 20436000.0 15802.0 22627.0 23044.0 21191.0 29033.0 20672.0 22348.0 25319.0 27091.0 23885.0 True False 18476.96649627355 24873.259023366554 23593.456354856662 20003.736972148967 23344.192065134364 19587.92392902381 20231.03565449132 24654.40307769798 27487.154623863302 28215.161426444025 0.6548594997211828 0.8815565024573864 0.8361978157156396 0.7089712041626285 0.8273634062307914 0.694233984097127 0.7170271099540915 0.8737998236150865 0.9741980280893089 1.0 14.784182983197425 -8.060592926417259 2.9147344391240533 0.9878532502608309 0.7661061582851633 0.6408120465559097 0.06809517712441578 0.17947516691137044 2.8499950250038104 0.054329391330833456 0.018435019520099568 8.697753064757077e-09 8.060592926417259 -0.22174709197566767 LGSSGLGSASS(ph)IQAAVR ddPTM_PC-9_Lapatinib_30min_R1 1 LGSSGLGSASSIQAAVR 17 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 LGSS(0.001)GLGS(0.211)AS(0.211)S(0.576)IQAAVR 79.347 0.006447800000000001 20100000.0 22470.0 19226.0 20256.0 22449.0 24405.0 25646.0 23292.0 17927.0 23802.0 16707.0 True False 22149.57367950667 19181.483378241926 18590.629870421177 24099.974347668693 22969.545882076105 24549.18036374594 24497.94579136872 18759.95386573106 21121.168113828364 19594.782689321826 1.1303811851701258 0.9789076859063547 0.9487540722027061 1.2299179189571707 1.1722276407073071 1.2528426955775331 1.250227990776283 0.9573953517715863 1.0778975428667725 1.0 14.25818195275616 -4.371148778282605 21.31059158740471 1.1036814025032808 46.84123456077541 0.004125533058844666 0.11693778092033665 6118.926740741261 857451.5489340595 0.030582894626690026 31322.37921607118 4.254526388746113e-05 4.371148778282605 45.73755315827213 LGSSS(ph)NLQFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGSSSNLQFK 10 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;A0A0J9YYG8;Q8TDM6-5 Q8TDM6-4 DLG5 Disks large homolog 5 1 LGS(0.063)S(0.123)S(0.814)NLQFK 73.9 0.026749000000000002 44314000.0 43464.0 45305.0 42441.0 46841.0 49084.0 33312.0 49239.0 47137.0 42385.0 41454.0 True False 50821.596746869596 49802.58098968581 43452.9543983888 44216.65063057098 39466.34255244221 31565.060077575527 44574.72546051089 45899.703695779855 43004.80044045795 48969.282050316535 1.037826053783059 1.017016768563465 0.887351265508454 0.90294667961719 0.8059408041124652 0.6445889904030457 0.9102589132246174 0.937316247532838 0.8781995291715731 1.0 15.579589424073955 -5.2875147646444445 1.9003122719747394 0.8548448310375586 1.047564238893181 0.324469252354621 0.08960915769457546 0.46362330328992973 2.996628391068721 0.027203527612107346 0.10797139146381897 5.158046290415158e-06 5.2875147646444445 0.19271940785562236 LGST(ph)GSQPNSEAESVPENVPKPPLLPPK ddPTM_PC-9_AZD4547_30min_R2 1 LGSTGSQPNSEAESVPENVPKPPLLPPK 28 1 A0A0J9YVR0;Q8IZ21-3;Q8IZ21;Q8IZ21-2 A0A0J9YVR0;Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 LGS(0.167)T(0.63)GS(0.203)QPNSEAESVPENVPKPPLLPPK 99.822 6.7707e-10 6529900.0 33557.0 40891.0 42870.0 33113.0 41202.0 43877.0 40928.0 39272.0 39842.0 34851.0 True False 44227.42797103944 54108.2160829123 42301.51578923963 25479.309440750207 35481.81349828905 41133.36425379318 44570.512711958094 33203.41478078232 41947.966780944895 33630.87709781882 1.3150839879197762 1.608885070869043 1.2578177983940586 0.7576165607171365 1.055036816170051 1.2230833033034678 1.3252854685389333 0.9872895876074482 1.2473051671811881 1.0 15.037498784586194 -5.5198803139006305 24.99738234572951 1.092037697389832 1.454826309951136 0.4559891846720291 0.16480204648048005 101.9251130014954 849730.5316895718 0.04567932454219876 0.08108890444881892 3.0207840958209036e-06 5.5198803139006305 0.362788612561304 LGSTAS(ph)LPFIQEHR ddPTM_PC-9_AZD4547_30min_R2 2 LGSTASLPFIQEHR 14 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5 Q8NEV8-2 EXPH5 Exophilin-5 1 LGS(0.041)T(0.177)AS(0.782)LPFIQEHR;LGS(0.153)T(0.132)AS(0.715)LPFIQEHR 79.514 0.007188600000000001 5381800.0 26913.0 33964.0 42027.0 64359.0 49444.0 42789.0 41112.0 48713.0 35692.0 38782.0 True False 35470.774174824466 44942.198797780315 41469.69452004602 49522.026886637956 42579.55406556487 40113.39706578748 44770.88835550287 41185.525163379745 37578.60625333783 37424.253984322066 0.94780177020186 1.2008842932876551 1.108096758252514 1.323260228711144 1.1377529150855616 1.0718556228961027 1.1963067687136393 1.1005035713105562 1.0041243913393818 1.0 15.19168593741374 -8.157947455375524 3.2776883862889243 0.9992042443148447 1.146351840220673 0.2614389694010655 0.09140222483318887 0.3344756704715444 6.400070361944796 0.07396882330947938 0.02369907091716244 6.951084126040852e-09 8.157947455375524 0.14714759590582827 LGSTAS(ph)LPFIQEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGSTASLPFIQEHR 14 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5 Q8NEV8-2 EXPH5 Exophilin-5 1 LGS(0.03)T(0.168)AS(0.802)LPFIQEHR;LGS(0.026)T(0.132)AS(0.841)LPFIQEHR 91.40100000000001 0.0025805999999999997 4510500.0 30857.0 34633.0 25473.0 26732.0 27949.0 24430.0 25815.0 22172.6 16559.7 17223.1 True False 36080.48064646961 38071.13535847673 26080.37292689047 25234.29270631333 22472.59408357525 23148.84779344291 23369.616315584983 21590.592743811605 16801.854284625508 20345.511692015407 1.7733877226901789 1.8712301727666913 1.2818735317001493 1.2402879361454704 1.1045479918990988 1.1377864633666437 1.148637432636132 1.0611968413792625 0.825826085820166 1.0 14.312422944367556 -5.414538734548478 1.3998232479419144 1.0606567892180518 1.9027124625889638 0.8771723963080766 0.1098681040386697 0.1696982325366676 0.5778625922288559 0.03474750041134064 0.14395088331926054 3.8500047511124135e-06 5.414538734548478 0.8420556733709119 LGSTAS(ph)LPFIQEHR ddPTM_PC-9_Lapatinib_30min_R1 2 LGSTASLPFIQEHR 14 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5 Q8NEV8-2 EXPH5 Exophilin-5 1 LGST(0.01)AS(0.989)LPFIQEHR;LGS(0.055)T(0.054)AS(0.89)LPFIQEHR 119.62 5.5835e-05 5544400.0 29919.0 40595.0 35082.0 23949.7 33498.0 31271.0 35383.0 32864.0 27941.0 37198.0 True False 29492.349573527375 40501.00477164939 32197.69338043621 25711.040831857124 31527.71349960191 29933.612226261375 37214.95860965137 34390.98141593047 24793.99034822614 43627.624736780584 0.676001724858141 0.928333940158441 0.7380116055984068 0.5893293752978774 0.7226548245479485 0.6861160195371725 0.8530136314819134 0.7882845243907333 0.5683094254572926 1.0 15.412954309286103 -7.243055127438035 24.187927724450766 0.7847589592051047 0.7272578344026687 0.07777484543848578 0.12718599487244098 2071.6796479861173 2725684.4721598034 0.04897707149230224 0.037850362905992176 5.714061002823219e-08 7.243055127438035 -0.05750112480243608 LGSVDS(ph)FER ddPTM_PC-9_AZD4547_30min_R2 2 LGSVDSFER 9 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 LGS(0.132)VDS(0.868)FER;LGS(0.002)VDS(0.998)FER 123.75 0.0014809 75403400.0 50924.8 61896.7 57827.0 69850.0 66632.0 62104.0 61842.5 62630.0 61399.6 56789.1 True False 67117.82709835771 81903.59781906033 57060.17619650945 53747.16167174222 57381.29695204109 58220.6270624148 67346.36269520294 52951.97259422481 64645.05750623226 54800.93089425675 1.2247570616613703 1.4945658127067327 1.0412264037377779 0.980770961271664 1.047086171998855 1.0624021547144273 1.2289273484268672 0.966260458173609 1.1796342954642618 1.0 15.741912779763009 -5.275293188204439 24.959770613448107 1.064441790830826 1.3596614358076946 0.5882580262445694 0.0991769482561376 431.927317243218 778183.7158799012 0.024739366764041495 0.051941865100432145 5.305261699801037e-06 5.275293188204439 0.2952196449768687 LGSVDS(ph)FER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LGSVDSFER 9 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 LGS(0.009)VDS(0.991)FER;LGS(0.303)VDS(0.697)FER;LGSVDS(1)FER;LGS(0.002)VDS(0.998)FER 111.46 0.0022338 19232500.0 49332.0 51448.0 58702.7 56738.0 57070.9 42754.100000000006 38005.8 37150.6 35558.9 29799.4 True False 57682.93324858669 56555.41743201316 60102.39499922945 53559.15380707791 45888.266831883586 40511.99973170846 34405.615485836126 36175.43611431441 36078.88164167043 35201.79532807941 1.6386361181577223 1.606606052473142 1.7073673214413465 1.5214892680304686 1.303577456894078 1.1508503857299932 0.9773824080612106 1.0276588389075247 1.0249159540136124 1.0 15.103361389232097 -6.495316532103076 1.3516140888677532 1.0073305358783617 1.6538600231439204 0.9822935865852888 0.03739343682855834 0.05043379580843109 0.18986415024919678 0.016191730117386227 0.018515571949859807 3.196564469693032e-07 6.495316532103076 0.6465294872655587 LGSVDS(ph)FER ddPTM_PC-9_Lapatinib_30min_R1 4 LGSVDSFER 9 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 LGS(0.23)VDS(0.77)FER;LGS(0.002)VDS(0.998)FER;LGS(0.004)VDS(0.996)FER;LGS(0.406)VDS(0.594)FER 135.55 0.0010520999999999998 61107700.0 86964.6 80542.0 93552.3 108621.9 134045.0 115288.9 121792.0 121471.8 117330.3 101991.3 True False 85724.46885664549 80355.5099474856 85860.79101632134 116610.3168780359 126160.73664260982 110358.26249855215 128097.79382716722 127115.82328260766 104115.32607116683 119620.36031013502 0.7166377749940814 0.6717544550037386 0.7177773983769438 0.9748366964930126 1.0546761129586788 0.9225708918818721 1.070869486557749 1.0626604279826566 0.870381311352274 1.0 16.868103442722862 -5.763400195380526 4.559533600245493 1.0012538241935307 0.6941237892364625 0.8334626217380366 0.05985207381494323 0.06834965936677342 3.514480683531835 0.016468041474208984 0.0271695692499497 1.724248292636152e-06 5.763400195380526 -0.30713003495706825 LGT(ph)SAEGAHLR ddPTM_PC-9_Lapatinib_30min_R1 1 LGTSAEGAHLR 11 0 Q15042-4;Q15042;Q15042-3 Q15042-4 RAB3GAP1 Rab3 GTPase-activating protein catalytic subunit 1 LGT(0.5)S(0.5)AEGAHLR 80.318 0.034184 2498800.0 8404.1 7093.0 8699.5 6227.5 13137.0 14016.0 16015.0 12895.0 21399.0 15762.0 True False 8284.255992876815 7076.576594292617 7984.260691041123 6685.491124331002 12364.307488335737 13416.568352891805 16844.178338003167 13494.148775511907 18988.819278540162 18486.440698455186 0.44812606861466237 0.3827982200426483 0.4318982123859205 0.3616429594740578 0.6688311552244319 0.7257518400506895 0.9111639505278453 0.7299484522534152 1.0271755168168721 1.0 14.174179860592782 -6.703121427496773 1.123605650359953 0.9166561502249061 0.39152424740328445 0.8773844973864287 0.08467994129928547 0.15466210257564889 0.41557460197290236 0.041883097887197115 0.0400496920429415 1.9809730739533098e-07 6.703121427496773 -0.5251319028216217 down LGT(ph)SESLPCTAEELSR ddPTM_PC-9_AZD4547_30min_R2 1 LGTSESLPCTAEELSR 16 0 Q9BZL6-2;Q9BZL6;Q9BZL6-3 Q9BZL6-2 PRKD2 Serine/threonine-protein kinase D2 1 LGT(0.391)S(0.391)ES(0.217)LPCTAEELSR 256.35 5.466e-57 18772000.0 11008.0 15271.0 21955.0 28204.0 24204.0 20547.0 16185.0 20653.0 14257.0 15520.0 True False 14508.315019376056 20207.052109318764 21663.862354857833 21702.003547456232 20843.692391451597 19262.19284186906 17625.433645500438 17461.55340872626 15010.59591375764 14976.64952392035 0.9687290202126796 1.3492371626273645 1.4465092689961678 1.4490559796297766 1.3917460215758235 1.2861483345192755 1.1768609272287178 1.1659185441201039 1.002266621101273 1.0 13.870427289336256 -7.767316225105603 1.221178493935057 1.0002992048337624 1.3346165593419301 0.4625074501505364 0.13072614278892222 0.4399836842696515 1.1924617364441938 0.11611861801670477 0.0451426324001797 1.7087706459212817e-08 7.767316225105603 0.3343173545081677 LGT(ph)SESLPCTAEELSR ddPTM_PC-9_Lapatinib_30min_R1 1 LGTSESLPCTAEELSR 16 0 Q9BZL6-2;Q9BZL6;Q9BZL6-3 Q9BZL6-2 PRKD2 Serine/threonine-protein kinase D2 1 LGT(0.863)S(0.108)ES(0.029)LPCTAEELSR 291.13 6.947399999999998e-97 38405000.0 31973.0 42419.0 32943.0 29884.0 31895.0 35258.0 28522.0 36649.0 33839.0 34407.0 True False 31517.059156869887 42320.781411715565 30234.55370365742 32081.769050101586 30018.99880798265 33750.09753041232 29998.729600782197 38351.84633375233 30027.695479532736 40354.20410555434 0.7810105503364863 1.048732897841753 0.7492293398866947 0.7950043808616675 0.7438877676651006 0.836346504124634 0.7433854852474512 0.9503804419840756 0.7441032761045022 1.0 15.300431361014954 -10.056019828854108 10.536360021637517 0.9999999989017966 0.8248002427189464 0.23291777830225524 0.09708399471703476 0.0 0.0 0.09146541412296252 0.022183621548800617 8.789823836676279e-11 10.056019828854108 -0.17519975618285022 LGTLS(ph)PAFSTR ddPTM_PC-9_AZD4547_30min_R2 1 LGTLSPAFSTR 11 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 1 LGT(0.008)LS(0.988)PAFS(0.005)TR 80.318 0.016301 15052000.0 24017.0 23694.0 32935.0 42527.0 30198.0 31656.0 28726.0 29766.0 30716.0 29051.0 True False 31653.90641536653 31352.62213857634 32498.260380653293 32723.057185600304 26005.528955422873 29676.54531572528 31282.558350364263 25166.348654633493 32339.58505204317 28033.93333243621 1.1291282618105498 1.1183811335635978 1.1592472592153777 1.167265998586742 0.9276446742966887 1.0585937037022384 1.1158818842652125 0.8977102269668016 1.1535871427155453 1.0 14.774886557066155 -6.2350046953840295 24.993417457986094 1.026621923970305 1.1428354657464586 0.3824619598013187 0.0734065795163124 797.893237617839 754390.8160727337 0.020682656057580903 0.0266936246678059 5.820969243835705e-07 6.2350046953840295 0.11621354177615362 LGTLS(ph)PAFSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGTLSPAFSTR 11 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 1 LGT(0.01)LS(0.982)PAFS(0.008)TR;LGT(0.003)LS(0.997)PAFSTR 100.02 0.00432 6341100.0 44943.0 52102.0 45271.0 52243.0 58820.0 56609.0 56100.0 54693.0 50514.0 50053.0 True False 52550.96223528805 57274.34222987772 46350.43233122355 49315.99408409128 47294.643242902996 53640.32438555095 50785.80187117244 53257.36670202359 51252.67168690086 59127.21268067003 0.888777939171621 0.9686629833068716 0.7839103219958906 0.8340659376323645 0.7998794649483729 0.9072019794886617 0.8589243356600069 0.900725136320092 0.8668203583974535 1.0 15.851534648085181 -9.688725889765836 0.6300238661576506 1.0093888277736278 0.8624100263773333 0.3792166456138565 0.05098861066735985 7.037199430645436 2.7959895162759603 0.219409556385232 0.02104205751011486 2.0477366828013726e-10 9.688725889765836 -0.1469788013962945 LGTLS(ph)PAFSTR ddPTM_PC-9_Lapatinib_30min_R1 1 LGTLSPAFSTR 11 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 1 LGT(0.002)LS(0.998)PAFSTR 83.226 0.038077 0.0 24469.0 20792.0 18760.0 19268.0 18999.0 22719.0 21490.0 20329.0 24708.0 23032.0 True False 24120.067572934957 20743.857401456666 17217.625215694177 20685.032996163758 17881.516173471162 21747.361330575684 22602.64704862243 21273.559554663167 21925.124853225403 27013.05051178911 0.8929042487226094 0.7679198390571836 0.6373817428794283 0.765742209941685 0.6619584176791606 0.8050686952621157 0.8367306402051157 0.7875289592109895 0.8116493486604476 1.0 14.721368948301429 -9.201149980239554 0.5256067722539054 1.0135812786279625 0.7487068147316066 0.5027207403771972 0.06977027964384437 2.1417972296842085 0.9255388752989538 0.13998882196962603 0.03535726802978985 6.292888253004429e-10 9.201149980239554 -0.26487446389635594 LGTS(ph)AEGAHLR ddPTM_PC-9_AZD4547_30min_R2 1 LGTSAEGAHLR 11 0 Q15042-4;Q15042;Q15042-3 Q15042-4 RAB3GAP1 Rab3 GTPase-activating protein catalytic subunit 1 LGT(0.215)S(0.785)AEGAHLR 100.02 0.0024483 3536700.0 12679.0 9617.7 15009.0 22221.0 23143.0 17798.0 13106.0 18406.0 14248.0 15659.0 True False 16710.65826041688 12726.433440625713 14809.97085329362 17098.291761027693 19929.99392725847 16685.088246439176 14272.408610313794 15561.775627803008 15001.12019213149 15110.78317622866 1.1058763841377224 0.842208725530927 0.9800928701426767 1.1315291577954514 1.3189252797043036 1.1041842141370353 0.9445181261528691 1.0298457364065563 0.9927427332641708 1.0 13.883290815378489 -4.396166599774306 22.620859156539616 1.043803562167364 46.732868452166436 0.0255670602165462 0.12095927917098792 5428.4304494401595 966606.0298553449 0.03236339724465555 33133.32275868126 4.016367093723198e-05 4.396166599774306 45.689064889999074 LGTS(ph)LSS(ph)GHVLMNGT(ph)LK ddPTM_PC-9_AZD4547_30min_R2 1 LGTSLSSGHVLMNGTLK 17 0 P80108 P80108 GPLD1 Phosphatidylinositol-glycan-specific phospholipase D 3 LGT(0.131)S(0.86)LS(0.011)S(0.998)GHVLMNGT(1)LK 74.029 0.012879 47127000.0 49391.0 25264.0 296910.0 348960.0 461380.0 97881.0 79733.0 248500.0 61739.0 97166.0 True False 65096.310603379585 33430.093935552984 292972.7794024523 268512.66337825573 397325.35099850927 91760.48559668008 86829.08253671211 210100.03496191715 65002.39749733338 93764.2479150284 0.6942551350955383 0.3565334834856053 3.1245681154287275 2.8636998573442285 4.237493072610957 0.9786297830686577 0.9260361434925483 2.2407264989990137 0.6932535475167491 1.0 16.516750310946996 LGTSES(ph)LPCTAEELSR ddPTM_PC-9_AZD4547_30min_R2 2 LGTSESLPCTAEELSR 16 0 Q9BZL6-2;Q9BZL6;Q9BZL6-3 Q9BZL6-2 PRKD2 Serine/threonine-protein kinase D2 1 LGT(0.002)S(0.011)ES(0.986)LPCTAEELSR;LGTS(0.079)ES(0.92)LPCTAEELSR 266.45 5.062999999999999e-69 63050000.0 35198.0 47493.1 53818.0 89202.0 55023.0 48925.0 48574.0 60378.0 44223.0 48701.0 True False 46390.231836119056 62844.31579681015 53104.33815594348 68637.85705716183 47384.00621611474 45865.71201579034 52896.99189969342 51047.967448412994 46560.53749695616 46995.99281343074 0.9871103696071175 1.3372271130922933 1.129975876172299 1.460504458957747 1.0082563082393934 0.9759494218554442 1.125563877535028 1.086219577296051 0.9907342032712598 1.0 15.520250127942838 LGTSES(ph)LPCTAEELSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LGTSESLPCTAEELSR 16 0 Q9BZL6-2;Q9BZL6;Q9BZL6-3 Q9BZL6-2 PRKD2 Serine/threonine-protein kinase D2 1 LGT(0.009)S(0.054)ES(0.929)LPCT(0.008)AEELSR;LGT(0.024)S(0.013)ES(0.963)LPCTAEELSR;LGTSES(0.999)LPCT(0.001)AEELSR 262.83 8.120199999999998e-69 62081000.0 117356.0 106011.0 85765.0 102494.0 93765.0 87785.0 85222.0 84971.0 61284.2 68440.4 True False 137222.05291334516 116535.07147770845 87809.96286557395 96751.59347003119 75392.42134768458 83181.40006333964 77149.15520615083 82740.60128421646 62180.36548668431 80848.10274609156 1.6972822892863604 1.4414076214465292 1.0861103709674738 1.196708273710337 0.932519363929406 1.0288602606368629 0.9542481837631056 1.0234080760567557 0.7691011090509516 1.0 16.30292629807311 -2.7840797224111835 0.5059048152662915 0.9300442060117907 7.664515395752709 0.8862147627294744 0.08671730095653771 8.397217884527624 0.31646507497418896 0.04495014409387675 51.47817753226989 0.00164406989748927 2.7840797224111835 6.734471189740918 LGTSES(ph)LPCTAEELSR ddPTM_PC-9_Lapatinib_30min_R1 3 LGTSESLPCTAEELSR 16 0 Q9BZL6-2;Q9BZL6;Q9BZL6-3 Q9BZL6-2 PRKD2 Serine/threonine-protein kinase D2 1 LGTSES(0.999)LPCTAEELSR;LGTSES(0.812)LPCT(0.188)AEELSR;LGT(0.101)S(0.006)ES(0.893)LPCTAEELSR 301.04 1.9912999999999996e-112 77669000.0 112669.0 125170.0 105986.0 70607.0 106574.0 120199.0 103140.0 106983.0 98083.0 101894.0 True False 111062.31939903574 124880.17655542213 97272.24019779108 75799.67431804712 100305.52685254575 115058.36896755431 108480.08453210426 111953.82074064313 87035.85968022133 119506.24213477934 0.9293432494829807 1.044967813602423 0.8139511247294287 0.6342737664912944 0.8393329508212718 0.9627812481777419 0.9077357181875089 0.9368031220861369 0.7282955109747501 1.0 16.866726450481295 -10.836735896637983 16.515910130910036 1.0000045754646618 0.8685970369928359 0.11103395140751937 0.11326332195761182 0.0 0.0 0.11770698820560167 0.028548137955589883 1.4563444442105374e-11 10.836735896637983 -0.13140753847182596 LGTSLS(ph)S(ph)GHVLMNGT(ph)LK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGTSLSSGHVLMNGTLK 17 0 P80108 P80108 GPLD1 Phosphatidylinositol-glycan-specific phospholipase D 3 LGT(0.099)S(0.126)LS(0.822)S(0.953)GHVLMNGT(0.999)LK 57.496 0.0449 0.0 11524.0 10322.0 30962.0 15995.0 16751.0 20242.0 13884.0 12491.0 17827.0 14561.0 True False 13474.785590625 11346.69994427849 31700.251504038897 15098.852006489662 13468.761798059644 19180.47388599555 12568.80700854471 12163.124485308483 18087.68614962946 17200.794035187417 0.7833816022132365 0.6596614040646444 1.8429527985272163 0.8777997094553983 0.7830313978823764 1.1150923525250247 0.7307108603726598 0.7071257559637395 1.0515611147152706 1.0 14.07018754472019 LGVADIIDCVVLTS(ph)SPEATETSQQLQLR ddPTM_PC-9_AZD4547_30min_R2 1 LGVADIIDCVVLTSSPEATETSQQLQLR 28 0 Q8NCF5;H3BSZ7;Q8NCF5-3;Q8NCF5-2 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 LGVADIIDCVVLT(0.021)S(0.574)S(0.404)PEAT(0.001)ETSQQLQLR 153.25 6.6552e-11 21373000.0 36796.0 41156.0 50953.0 86134.0 62640.0 56074.0 38622.0 59309.0 47356.0 62005.0 True False 48496.36259565422 54458.872150554846 50277.329927901235 66277.13705703437 53943.517245105235 52567.68391565512 42059.283179272046 50144.156835236805 49859.14148080991 59834.223822853164 0.8105121032276422 0.9101625904229538 0.8402771309736325 1.107679398553849 0.9015495447022407 0.8785554580149387 0.7029302043558534 0.8380514299591312 0.8332880130345509 1.0 15.868683288993859 -7.007837163520418 18.26986377289257 0.8244535100397364 0.9174391239924308 0.08723462096650991 0.09986570266813362 20.457994213464254 47692.57546192149 0.03617047117827366 0.03032445652471402 9.82116113373166e-08 7.007837163520418 0.09298561395269433 LGVADIIDCVVLTS(ph)SPEATETSQQLQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGVADIIDCVVLTSSPEATETSQQLQLR 28 0 Q8NCF5;H3BSZ7;Q8NCF5-3;Q8NCF5-2 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 LGVADIIDCVVLTS(0.692)S(0.308)PEATETSQQLQLR 188.73 9.800399999999998e-62 0.0 2376.1 1250.3 659.25 2779.7 3727.9 3498.4 2351.7 2994.6 2512.5 1138.1 True False 2778.326799885811 1374.4215210551638 674.9690202195478 2623.962420908993 2997.4447559540636 3314.9377454187766 2128.929951166423 2915.994923040971 2549.2405593169906 1344.4285208053575 2.066548542291784 1.0223091073907296 0.5020490191737519 1.9517307021552563 2.2295307705600402 2.4656853779277297 1.5835203718313884 2.1689475326618277 1.8961517997177793 1.0 10.392777338183807 -5.8648694387536455 11.844030288151089 1.9738980380779976 1.1799277140571236 0.2679702020527984 0.5217975384473882 0.49179948478165064 52.696810844622526 0.1441487223429411 0.21390970049264196 1.3649934306760106e-06 5.8648694387536455 -0.793970324020874 LGVADIIDCVVLTS(ph)SPEATETSQQLQLR ddPTM_PC-9_Lapatinib_30min_R1 1 LGVADIIDCVVLTSSPEATETSQQLQLR 28 0 Q8NCF5;H3BSZ7;Q8NCF5-3;Q8NCF5-2 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 LGVADIIDCVVLT(0.001)S(0.611)S(0.388)PEATETSQQLQLR 186.43 2.2284000000000003e-24 730920.0 634.32 1295.4 2979.7 1219.2 2177.5 770.82 970.69 2263.9 2802.7 1062.7 True False 625.2744804799586 1292.4005808891386 2734.720567974622 1308.864035131973 2049.4237311297143 737.8538254691821 1020.9475785773528 2369.0890587732797 2487.0304122605967 1246.3862790412586 0.5016699004107541 1.0369181710530984 2.194119603176485 1.0501271212154015 1.644292596598677 0.5919945027289226 0.819126137494616 1.9007663182842667 1.995392964509897 1.0 10.283535541219806 -7.7708030127594885 24.9886383985045 1.7110597921380226 1.1550844523069792 0.15646893938025896 0.5313405125029746 363.9742944809417 971318.0512427011 0.2920941366540815 0.14329626128067258 1.6951064923078885e-08 7.7708030127594885 -0.5559753398310434 LGVADIIDCVVLTSS(ph)PEATETSQQLQLR ddPTM_PC-9_Lapatinib_30min_R1 2 LGVADIIDCVVLTSSPEATETSQQLQLR 28 0 Q8NCF5;H3BSZ7;Q8NCF5-3;Q8NCF5-2 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 LGVADIIDCVVLT(0.005)S(0.204)S(0.791)PEATETSQQLQLR;LGVADIIDCVVLTS(0.267)S(0.732)PEATETSQQLQLR 170.77 1.3391999999999998e-38 18770000.0 33011.89 50472.9 47651.7 43991.8 35645.5 63312.5 40342.2 47367.0 46397.9 43719.3 True False 32541.1343949608 50356.033101095745 43733.961166881345 47227.103724342815 33548.90177174936 60604.77196364603 42430.92172009938 49567.843741735 41172.07991045277 51276.12275269455 0.6346254874204733 0.9820561773744787 0.8529108446403182 0.9210350000938993 0.6542792233639853 1.1819296918361726 0.8274986376162703 0.9666847078278792 0.8029483841636443 1.0 15.645999556152399 -6.740750653271233 24.999980983250833 0.9457106834258554 0.8272624544697049 0.21048528251562826 0.13927900507501365 467.8846313093062 565384.3212743816 0.04406110207084225 0.04401369399720788 1.8165583259666504e-07 6.740750653271233 -0.11844822895615048 LGVAGQWR ddPTM_PC-9_Lapatinib_30min_R1 1 LGVAGQWR 8 0 P09936;D6RE83;D6R956;D6R974;D6RF53 P09936 UCHL1 Ubiquitin carboxyl-terminal hydrolase isozyme L1;Ubiquitin carboxyl-terminal hydrolase 0 94.163 0.031412 10607000.0 44688.0 45738.0 43754.0 38194.0 45217.0 43079.0 45098.0 43118.0 49328.0 38912.0 False True 44050.74092522449 45632.096471134326 40156.71501532423 41002.914171448945 42557.4249600424 41236.6115920538 47432.95377379128 45121.419689997856 43772.16119313188 45637.88735301915 0.9652230521645814 0.9998731124024206 0.8798986400203666 0.8984402335340884 0.9325020816772545 0.9035609223774863 1.0393328115056444 0.9886833573380315 0.9591189192116746 1.0 15.477944388181578 -7.25202476655418 24.995253605386743 0.995840719463184 0.9295094630124912 0.4401435660498155 0.036937649830342284 693.8212783479238 1842058.3091842802 0.015318140932726444 0.01169871016084345 5.597256810534302e-08 7.25202476655418 -0.06633125645069282 LGVIEDHSNR ddPTM_PC-9_AZD4547_30min_R2 4 LGVIEDHSNR 10 0 P14625;Q58FF3 P14625 HSP90B1;HSP90B2P Endoplasmin;Putative endoplasmin-like protein 0 ;;; 188.91 0.00045809 67175400.0 276980.0 287540.0 387366.0 523666.0 428045.0 334226.0 304645.0 421968.0 318637.0 336267.0 False True 365053.8784581019 380481.6818488329 382229.2737395519 402942.8942590494 368618.3403445251 313326.79538455873 331757.8148244345 356762.5414600004 335479.50130967156 324494.39468170924 1.1249928641022497 1.1725369931953387 1.177922577413005 1.2417561007618911 1.135977528074395 0.9655846156969689 1.0223838077383427 1.0994413071755598 1.033852993481559 1.0 18.30783403175292 -6.589957705932279 6.113506562008454 1.0311052163414796 1.1800008807236915 0.7632840496531402 0.0412119770144019 0.10521781230214951 7.18420358940811 0.01432236383190711 0.01434735281971533 2.5706461147245507e-07 6.589957705932279 0.1488956643822119 LGVIEDHSNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LGVIEDHSNR 10 0 P14625;Q58FF3 P14625 HSP90B1;HSP90B2P Endoplasmin;Putative endoplasmin-like protein 0 ;;;;; 184.71 0.00010564 61091000.0 377137.0 389367.0 413601.0 443411.0 450661.0 412023.0 414095.0 369057.0 351471.0 304813.0 False True 440978.8453047163 428020.782523143 423462.81643052824 418568.1192278582 362357.2121470568 390415.7885549625 374868.92381182115 359369.6447982135 356610.59845719545 360073.18400162004 1.2246922706211087 1.1887049676024117 1.176046523999474 1.1624529063124427 1.0063432331173723 1.084267881923709 1.0410909239221062 0.9980461216367521 0.990383661715811 1.0 18.457930635063484 -6.088253700237779 0.6925036115300551 0.9993100216848406 1.2374419606795037 0.8811063136293422 0.03013135256604591 0.29160416752379503 0.2823487454673159 0.01823990165531216 0.042145857816651526 8.161054906885624e-07 6.088253700237779 0.23813193899466312 LGVIEDHSNR ddPTM_PC-9_Lapatinib_30min_R1 2 LGVIEDHSNR 10 0 P14625;Q58FF3 P14625 HSP90B1;HSP90B2P Endoplasmin;Putative endoplasmin-like protein 0 ; 176.6 0.0013770999999999998 48995000.0 310420.0 296140.0 295070.0 251930.0 253030.0 260230.0 250910.0 251980.0 279000.0 210158.0 False True 305993.35387594445 295454.30602478754 270810.4836031381 270457.7726138439 238147.2728761204 249100.5695257584 263900.8920879413 263687.9106982164 247576.08199975255 246483.5302820667 1.2414352939759379 1.1986776791401863 1.0986960601109232 1.0972650882772652 0.9661792518290915 1.0106175014642838 1.0706633899065905 1.069799310308732 1.0044325546475077 1.0 17.91113172520145 -5.344108899131568 1.2836224445664854 1.0276474146062489 1.2567871039039338 0.8333021858819425 0.03432661022783879 0.2599947683308796 0.6855378207115431 0.011638848825696886 0.06007583773974625 4.527840302910652e-06 5.344108899131568 0.2291396892976849 LGVSVS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 4 LGVSVSPSR 9 0 E7ERS3;Q86VM9;H3BP01 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 LGVSVS(0.997)PS(0.003)R;LGVS(0.009)VS(0.634)PS(0.357)R;LGVS(0.013)VS(0.983)PS(0.005)R;LGVS(0.015)VS(0.953)PS(0.032)R 166.86 0.00084761 1516070000.0 434027.0 386607.0 556540.0 781670.0 666560.0 564593.0 474753.0 598380.0 500608.0 533826.0 True False 572038.5576775738 511570.15223805944 549159.9159632233 601468.058181113 574019.6496631133 529288.9104574572 517005.0972815723 505914.1204044738 527069.1168685127 515136.9142239881 1.1104592621542244 0.9930760893124857 1.0660465223900488 1.1675887352922005 1.1143050203028593 1.0274723007470508 1.003626575782088 0.9820964222037792 1.0231631675289656 1.0 18.974596400364263 -6.922951300116926 4.755936857308472 1.0024117899425238 1.0875313085385474 0.4958162451949625 0.042360058082160666 0.20627632280585015 8.613772502042849 0.016941267973775733 0.014792459529142417 1.194122000573488e-07 6.922951300116926 0.08511951859602362 LGVSVS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LGVSVSPSR 9 0 E7ERS3;Q86VM9;H3BP01 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 LGVS(0.011)VS(0.8)PS(0.189)R;LGVSVS(0.998)PS(0.002)R;LGVS(0.002)VS(0.711)PS(0.287)R;LGVS(0.002)VS(0.775)PS(0.223)R;LGVS(0.001)VS(0.524)PS(0.475)R 147.73 0.00036552 851797000.0 331551.0 309030.0 344808.0 364076.0 392067.0 316113.0 335811.0 329633.0 309937.0 222704.0 True False 387676.03586925584 339708.4560918797 353029.53041162214 343678.00207031815 315244.28582650877 299535.4777948679 304000.5510189004 320980.4830250326 314469.24228180264 263078.4722761055 1.4736136807970475 1.2912818489205369 1.3419172133594854 1.3063706775278139 1.1982899364553643 1.1385784446874092 1.1555508453000536 1.2200940664128457 1.1953438818504376 1.0 18.005133671966817 -1.5228787452803376 0.15324666208176438 1.009198251071523 2.5656246534928897 0.8084244084000504 0.0536994871921398 31.234556258937587 0.3132790963272811 0.19211580212077703 10.85621647437493 0.029999999999999995 1.5228787452803376 1.5564264024213668 LGVSVS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 4 LGVSVSPSR 9 0 E7ERS3;Q86VM9;H3BP01 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 LGVS(0.001)VS(0.766)PS(0.233)R;LGVS(0.006)VS(0.773)PS(0.22)R;LGVS(0.006)VS(0.986)PS(0.008)R;LGVS(0.027)VS(0.679)PS(0.294)R 105.17 0.0026544 908670200.0 331263.0 293535.0 344621.0 305515.0 320860.0 343803.0 276755.0 267455.0 351559.0 226162.0 True False 326539.12887380546 292855.337742236 316287.5916555302 327983.59226816316 301987.6456350314 329099.34713393677 291084.0197273852 279881.93569248036 311962.7233396093 265253.80035807815 1.2310441110852905 1.104057085504137 1.1923960796360287 1.2364897009030718 1.1384856512041093 1.2406960680286978 1.0973792621799863 1.0551476936980924 1.176091437402505 1.0 18.017013895580533 -8.63917148752035 0.4365653968890234 0.9949976627427044 1.1921392414192702 0.47050929980823897 0.056916971782350716 1.2529440611933262 0.5781249060378632 0.08407011786652417 0.039177061020606314 2.2952421592584914e-09 8.63917148752035 0.1971415786765658 LGVSVSPS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LGVSVSPSR 9 0 E7ERS3;Q86VM9;H3BP01 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 LGVS(0.001)VS(0.404)PS(0.594)R 82.505 0.015677 345280000.0 81880.0 101240.0 92028.0 88240.0 91531.0 98482.0 100250.0 94197.0 80338.0 57330.0 True False 95740.66679628384 111290.43812814904 94222.2965381337 83296.19887793993 73596.15761078124 93317.43055234737 90753.5942528526 91724.42855997148 81512.79126543601 67723.47517596983 1.413699851454984 1.6433066649190202 1.3912797046121814 1.2299457265225475 1.086715609610288 1.377918518060027 1.340061094281448 1.3543963643572423 1.2036120570250803 1.0 16.047368385424775 -1.5228787453668173 0.050849617953512796 0.47397399455877703 2.8804489461685883 0.4926274647225668 0.12322499481160565 469.3570357856902 1.8069648472592017 19.912835647558406 88.20242492782377 0.02999999999402619 1.5228787453668173 2.406474951609811 LGVSVSPS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 LGVSVSPSR 9 0 E7ERS3;Q86VM9;H3BP01 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 LGVS(0.006)VS(0.45)PS(0.544)R 113.67 0.0020857 496860000.0 180960.0 153330.0 172590.0 145670.0 164000.0 175450.0 114590.0 148150.0 154390.0 129070.0 True False 178379.47721600012 152974.9738055673 158400.31641666585 156383.05774087505 154353.84243640563 167946.41249392615 120522.90950682387 155033.58984816482 137000.97240122512 151379.57752503586 1.1783589314516278 1.0105390456666297 1.0463783755141534 1.033052544455752 1.0196477289737307 1.1094390355670691 0.7961636006474601 1.0241380798048842 0.905016215800756 1.0 17.207811060271 -7.231932153013643 24.9996554709928 0.933340915792621 1.0591756697272932 0.44623931714177933 0.07335714581674913 664.3244201161962 562842.043035689 0.02650532852012856 0.020527456277155336 5.862297401987185e-08 7.231932153013643 0.12583475393467214 LGYLVS(ph)PPQQIR ddPTM_PC-9_AZD4547_30min_R2 1 LGYLVSPPQQIR 12 0 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;H3BSK8 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 LGYLVS(1)PPQQIR 109.6 0.0012929999999999999 26855000.0 41374.0 47751.0 49830.0 72261.0 62252.0 55677.0 48294.0 60254.0 47516.0 57309.0 True False 54530.07136733875 63185.576928300725 49169.22164165639 55602.34287132086 53609.384347737745 52195.50838841406 52592.072442125296 50943.128799176484 50027.59875416344 55302.62935350201 0.9860303570518327 1.142542003281794 0.8890937414089295 1.0054195166002513 0.969382197093364 0.9438160354867252 0.9509868347479383 0.9211701033876889 0.9046151935087959 1.0 15.755060454314666 -5.267273425465428 24.997043355493542 0.9480080559958337 1.0642861809280195 0.4656257865040365 0.0498042246001455 348.9783066670915 1495266.2666950212 0.012289950361703477 0.02673670692154644 5.404139790674785e-06 5.267273425465428 0.11627812493218581 LGYLVS(ph)PPQQIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LGYLVSPPQQIR 12 0 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;H3BSK8 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 LGY(0.001)LVS(0.999)PPQQIR;LGY(0.001)LVS(0.999)PPQQIR 126.5 0.0016986 4104300.0 74004.6 93046.2 100955.0 95721.0 125644.0 100329.0 103623.0 90929.0 98288.0 72202.8 True False 86532.11712252408 102283.21181508686 103362.15007396978 90358.06270166929 101024.9601430006 95067.57062088976 93807.07927444763 88542.21009723906 99725.27605737238 85292.59608294959 1.0145325748833933 1.199203875980201 1.2118537226073762 1.0593892887700755 1.1844516966601746 1.1146051942003703 1.099826756160845 1.0380996025860103 1.1692137493433379 1.0 16.380132891807996 -7.2597767578105215 2.741558748352341 1.0773639689991927 1.1380883530024355 0.1285303842446327 0.07013434714305901 0.5901214818106632 8.851708394905941 0.031038659721819562 0.020957008817710284 5.498234292421403e-08 7.2597767578105215 0.06072438400324276 LGYLVS(ph)PPQQIR ddPTM_PC-9_Lapatinib_30min_R1 2 LGYLVSPPQQIR 12 0 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;H3BSK8 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 LGY(0.009)LVS(0.991)PPQQIR;LGYLVS(1)PPQQIR 103.97 0.0019659000000000005 39312000.0 88495.0 83598.0 91361.0 75120.0 77044.0 77180.0 71268.0 72219.0 72550.0 61794.0 True False 87233.04507200468 83404.43396724598 83849.6512436588 80644.57539297387 72512.42339433196 73879.19131536748 74957.90832299783 75574.55838842146 64378.65501463096 72475.01056467064 1.2036292839745806 1.150802646559435 1.1569456919062935 1.1127225062080315 1.000516216960437 1.019374688458222 1.0342586739757929 1.0427671248282888 0.8882876251143811 1.0 16.14519601813756 -6.073483679959418 1.6528405065993523 0.998633460452138 1.1759457297972264 0.779748000686789 0.0420490951226956 0.1778985837760473 0.9725706577038244 0.01448237639208555 0.022803685244077644 8.443379700833424e-07 6.073483679959418 0.17731226934508848 LHAEFAAER ddPTM_PC-9_AZD4547_30min_R2 2 LHAEFAAER 9 0 Q9H773 Q9H773 DCTPP1 dCTP pyrophosphatase 1 0 ; 117.31 0.0015659 7291700.0 20685.7 18186.3 45295.0 61221.0 44381.0 39821.0 23552.2 57065.0 29747.0 33038.0 False True 27263.32231071104 24064.665822520074 44694.35870477278 47107.44430502119 38219.464221823364 37330.98657497775 25648.300173342934 48246.91547324668 31319.365690295894 31881.349675984577 0.8551495651154261 0.7548195439369176 1.4018966938040243 1.4775862623063933 1.1988032065848557 1.170934949567027 0.8044922951509533 1.5133272575843886 0.9823726413279168 1.0 14.960425085717015 -5.248382181428082 24.912177601425967 1.207620853977135 0.8049844902069713 0.3396771243830985 0.21607715105326084 809.8176901623061 1545066.3583314158 0.05503572843155767 0.14364877511086177 5.644400459854556e-06 5.248382181428082 -0.40263636377016365 LHAEFAAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LHAEFAAER 9 0 Q9H773 Q9H773 DCTPP1 dCTP pyrophosphatase 1 0 102.62 0.002617 2674100.0 13419.0 12859.0 34783.0 18602.0 32804.0 32034.0 16789.0 20524.0 26930.0 14938.0 False True 15690.57166266895 14135.556537829601 35612.35863526207 17559.790248497695 26376.291685484368 30354.080647365958 15198.624378166034 19985.26674697554 27323.800303445394 17646.14115085706 0.8891786327973961 0.801056526579073 2.0181386021346883 0.9951065277319755 1.4947342571949953 1.7201540205231602 0.8613001702883833 1.1325573436209804 1.5484292044279775 1.0 14.107065109720827 LHAEFAAER ddPTM_PC-9_Lapatinib_30min_R1 2 LHAEFAAER 9 0 Q9H773 Q9H773 DCTPP1 dCTP pyrophosphatase 1 0 ; 128.86 0.001105 8192500.0 28405.0 34654.0 35458.0 30272.0 32708.0 39451.0 33868.0 30451.0 35757.0 30408.0 False True 27999.939491160978 34573.7607921354 32542.780111838158 32498.303864431644 30784.179746402155 37763.77269477271 35621.51932260328 31865.864626840885 31729.670122097312 35663.982283886886 0.7851041218078288 0.9694307415511461 0.9124830719350459 0.9112359804842796 0.8631728083913545 1.0588770596107693 0.9988093600724226 0.8935027045826567 0.8896838796499988 1.0 15.122180184599959 LHDALDAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LHDALDAK 8 0 P07954-2;P07954 P07954-2 FH Fumarate hydratase, mitochondrial 0 110.41 0.0031578 2550400.0 30169.0 32630.0 28739.0 35083.0 41082.0 35720.0 38463.0 30758.0 32426.0 28991.0 False True 35276.01583508901 35869.29075584258 29424.24675326444 33117.41325062064 33032.277009604564 33846.78031853379 34819.50619199479 29950.63509079483 32900.16890603492 34246.83880737028 1.030051738016101 1.0473752324294274 0.8591813953623081 0.9670210274559246 0.9645350683431742 0.9883183819947086 1.0167217589876139 0.874551816570852 0.9606775413955714 1.0 15.063683204194554 -5.1548705131279835 22.937308536141988 0.9536708784466563 1.038719787210343 0.3335659579525946 0.04796473120261183 18.15984109092426 3898.236875498701 0.012178058202392424 0.03222013820982114 7.00050688181249e-06 5.1548705131279835 0.08504890876368676 LHDFGYR ddPTM_PC-9_AZD4547_30min_R2 4 LHDFGYR 7 0 P43490;A0A0C4DFS8 P43490 NAMPT Nicotinamide phosphoribosyltransferase 0 ;;; 148.21 0.0010321 50079600.0 68102.5 52732.6 76350.90000000001 89536.7 106198.6 105281.59999999999 101082.5 103648.2 107974.1 112868.0 False True 89757.67838000144 69777.38170780333 75338.43717920815 68895.39714322524 91454.75751127144 98698.32490877123 110078.6466772506 87631.75228869112 113681.39049250603 108916.52567434529 0.8240960480907388 0.6406500875398289 0.6917080462561406 0.6325522845745086 0.8396775139955931 0.9061831921068989 1.010669831742338 0.8045771910748004 1.0437478590935543 1.0 16.732863342170447 -6.53896770346296 2.6958202422144337 0.9458217878258575 0.6933258070599404 0.6964053055843422 0.07925341452685457 0.15353156344457697 2.261042006419034 0.02654502494977888 0.02807845085443522 2.890894857285054e-07 6.53896770346296 -0.25249598076591706 LHDFGYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LHDFGYR 7 0 P43490;A0A0C4DFS8 P43490 NAMPT Nicotinamide phosphoribosyltransferase 0 ;; 158.38 0.00038461 26906900.0 29242.5 30556.6 34861.0 35068.1 43418.0 35495.1 37139.1 34018.5 30849.9 30406.699999999997 False True 34192.67768429815 33590.05730646583 35692.218451078734 33103.34804931418 34910.55457872087 33633.67447044763 33621.01558420073 33125.55042058014 31301.021425223153 35919.19401069523 0.9519333221707871 0.9351562091416672 0.9936809395124815 0.9216060928164868 0.9719192075503132 0.9363705226913758 0.9360180959013111 0.9222242127904301 0.871428835956147 1.0 15.132467357417516 -7.170064970052138 2.1369401377840007 0.924425766395949 0.9539951853782592 0.0689087770650022 0.034642197233982104 0.6902362635185214 6.174258094636424 0.015534210441326152 0.010757635768184446 6.759818415701757e-08 7.170064970052138 0.029569418982310247 LHDFGYR ddPTM_PC-9_Lapatinib_30min_R1 4 LHDFGYR 7 0 P43490;A0A0C4DFS8 P43490 NAMPT Nicotinamide phosphoribosyltransferase 0 ;;; 148.21 0.0010321 48207400.0 137503.5 113585.6 110813.7 122099.6 120748.0 112366.3 100317.8 101993.6 117607.40000000001 98997.7 False True 135542.6748749467 113322.59952187855 101703.0253392521 131079.21189632514 113645.84003970183 107560.65528763887 105511.76482523477 106732.59500194297 104361.21615117468 116109.32053885657 1.1673711830015117 0.9759991617895531 0.8759247308248321 1.128929282231557 0.9787830943483101 0.9263739964066292 0.9087277777146644 0.9192422667414057 0.8988185932605615 1.0 16.825124261932828 -6.590539097312559 4.4891409896854295 0.9250388426372244 1.0247063628924715 0.278939335373917 0.07908304650020995 0.303256424821072 12.017635882222777 0.026803754149340404 0.027029592686537936 2.567207085169806e-07 6.590539097312559 0.09966752025524717 LHDFLAHSSEESEETS(ph)SPPR ddPTM_PC-9_AZD4547_30min_R2 1 LHDFLAHSSEESEETSSPPR 20 0 P46100-4;P46100;A0A096LNW1;A0A096LNL9;P46100-6;A0A087WWG0 P46100-4 ATRX Transcriptional regulator ATRX 1 LHDFLAHSSEES(0.012)EET(0.134)S(0.427)S(0.427)PPR 82.56 0.00059523 3523400.0 10693.0 9589.9 17204.0 32900.0 25455.0 21081.0 14570.0 24741.0 16465.0 22901.0 True False 14093.151571783088 12689.647634284333 16975.86371910609 25315.413299933003 21921.012635283438 19762.801737452744 15866.701774169982 20917.846941620894 17335.306286036288 22099.242960521882 0.6377210113920696 0.5742118703773309 0.7681649434522168 1.1455330549176048 0.9919350031330559 0.8942750560621936 0.7179749008829976 0.946541335329385 0.7844298701545616 1.0 14.431709328541377 -5.5235126505793 24.999904730974198 0.9194804748599308 0.6222718899860584 0.5679082910620459 0.1120678490313779 15.603860543200426 615380.0897870408 0.03228245761291434 0.056568647825104214 2.99562433151015e-06 5.5235126505793 -0.29720858487387236 LHELRIARLRQEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LHELRIARLRQEER 14 3 Q9BYN8 Q9BYN8 MRPS26 28S ribosomal protein S26, mitochondrial 0 ; 76.07300000000001 0.011311 46410000.0 157062.0 139135.0 178292.0 178048.0 207233.0 180713.0 183012.0 184043.0 176812.0 145711.0 False True 183649.4944840983 152947.40328881884 182543.157456175 168072.54779940433 166627.18128453795 171236.09215294526 165675.7784678611 179212.06625967706 179397.54100455984 172127.2508523583 1.0669402641050905 0.8885716964131907 1.060512827296306 0.9764435728051459 0.9680464915312101 0.994822675113905 0.9625191690882756 1.0411603355786803 1.042237879918489 1.0 17.39311599457659 -7.772459676014983 24.99446056194574 1.0312743426698425 0.9862295127164667 0.11894975437155852 0.048813640094545134 404.9451689904565 918417.2235360942 0.024352354906888536 0.011870352694737598 1.688652642604171e-08 7.772459676014983 -0.045044829953375776 LHGELQDR ddPTM_PC-9_AZD4547_30min_R2 3 LHGELQDR 8 0 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 0 ;; 124.08 0.0027843000000000004 34055600.0 66247.0 60565.0 197608.0 332074.0 201993.0 155315.0 76306.2 265234.0 97863.4 120612.0 False True 87312.16797679929 80141.4518368733 194987.5888052265 255519.46979215674 173949.758602978 145603.12849734246 83097.30397530319 224248.17977098253 103036.25953190913 116389.41059143575 0.7501727823271919 0.6885630868790594 1.6753035161394159 2.195384171925333 1.4945496993158387 1.250999792485042 0.7139593159982693 1.926706034779794 0.8852717700719315 1.0 16.828600278540534 -6.987888884676085 21.189805627291346 1.1763915061051478 1.3858363994783347 0.04004568781883522 0.503380152973111 167.00810394930096 292189.8494621967 0.19300496663173072 0.1699550342978065 1.0282793523046139e-07 6.987888884676085 0.20944489337318695 LHGELQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LHGELQDR 8 0 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 0 ;;; 131.03 0.0015138 21706600.0 60688.0 78420.0 158690.0 86048.0 125982.0 98889.0 67449.2 80943.0 98171.0 65393.7 False True 70961.27975736304 86205.019340275 162473.7714351765 81227.00953137988 101296.73146935385 93703.08675586476 61059.92348607993 78818.33201619779 99606.56515371488 77249.06015375562 0.9186037942225127 1.1159361572644837 2.103245930912177 1.051495116829986 1.3113005034331036 1.2129996995349748 0.7904293380987029 1.0203144460180966 1.289421061634396 1.0 16.237229760207054 -7.0266566077002945 9.87913302373169 1.0230116437015302 1.314975798755112 0.14233360934377848 0.3182987638959668 0.9901075999251486 358.2859262187486 0.12337836625280714 0.097811812233762 9.404666342105571e-08 7.0266566077002945 0.29196415505358186 LHGELQDR ddPTM_PC-9_Lapatinib_30min_R1 4 LHGELQDR 8 0 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 0 ;;; 128.61 0.00027123 43519100.0 46589.6 48826.3 76224.7 46964.7 57607.3 58508.4 44872.1 52323.5 70237.5 37099.0 False True 45925.22376051375 48713.24570222894 69957.79940185079 50418.64070764647 54218.95187430943 56006.132121741895 47195.35777712849 54754.64082632784 62326.61311633556 43511.51271868979 1.0554729286804865 1.119548428876039 1.6077997530019532 1.1587425386382812 1.2460828982169678 1.2871566310238902 1.0846636861893417 1.2583943284235375 1.4324166001602605 1.0 15.409109553950648 -7.941187603375919 24.99968121944121 1.2592927481554057 1.2300283837190418 0.0 0.17672724374457355 788.8597222580755 335320.3594422705 0.09622230279359327 0.04622369527907874 1.1450182179464194e-08 7.941187603375919 -0.029264364436363932 LHGS(ph)VPNLSR ddPTM_PC-9_AZD4547_30min_R2 4 LHGSVPNLSR 10 0 J3QLK7;Q9BZF2-2;Q9BZF2 J3QLK7 OSBPL7 Oxysterol-binding protein-related protein 7 1 LHGS(1)VPNLSR;LHGS(1)VPNLSR;LHGS(1)VPNLSR;LHGS(1)VPNLSR 79.88600000000001 0.010434 28694900.0 51411.9 58545.0 80679.0 111862.0 101974.0 84261.0 68059.0 102270.0 78912.0 74164.0 True False 67759.81476604822 77468.5263401262 79609.14374527785 86073.94415067183 87816.67029936731 78992.1463497704 74116.11915224664 86466.52143080566 83083.12721795899 71567.54093376458 0.9467953471918171 1.0824533766197577 1.1123638273243974 1.202695286545235 1.2270460763859585 1.1037426369431536 1.0356108116225589 1.208180696201788 1.1609051552414247 1.0 16.127017788942652 -4.727512689332396 1.8410672515808857 1.140633861062094 0.8667825609086486 0.3832988935093139 0.07004412398662542 1.0154492136211808 3.214400976819245 0.019294323994743276 0.508015685307654 1.872782362761875e-05 4.727512689332396 -0.2738513001534455 LHGS(ph)VPNLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LHGSVPNLSR 10 0 J3QLK7;Q9BZF2-2;Q9BZF2 J3QLK7 OSBPL7 Oxysterol-binding protein-related protein 7 1 LHGS(1)VPNLSR;LHGS(1)VPNLSR;LHGS(1)VPNLSR;LHGS(1)VPNLSR 81.278 0.009353499999999999 25309100.0 74293.7 70458.0 83750.0 95932.0 110138.0 85339.0 89074.0 74847.8 77496.3 70714.9 True False 86870.15604253866 77452.60459929987 85746.91762364355 90557.24105574054 88557.24953224826 80863.67260927656 80636.26588008567 72883.12455779957 78629.5367789043 83534.95159115974 1.0399258560381075 0.9271879988435457 1.0264795273158198 1.0840640873170022 1.0601221147007884 0.9680220203519472 0.9652997259726571 0.8724865839930956 0.9412770975643378 1.0 16.350092336858197 -7.0720415676132875 2.680669549845267 0.9332458234338067 1.024444587828271 0.3786828821586099 0.04915426103051923 0.2996929483702459 4.233118067960189 0.021821294441557153 0.016694406718703734 8.471463273719029e-08 7.0720415676132875 0.0911987643944644 LHGS(ph)VPNLSR ddPTM_PC-9_Lapatinib_30min_R1 4 LHGSVPNLSR 10 0 J3QLK7;Q9BZF2-2;Q9BZF2 J3QLK7 OSBPL7 Oxysterol-binding protein-related protein 7 1 LHGS(1)VPNLSR;LHGS(1)VPNLSR;LHGS(1)VPNLSR;LHGS(1)VPNLSR 74.987 0.014238999999999998 28748000.0 96331.0 86237.0 84595.0 65226.0 68514.0 67943.0 63240.0 65465.0 77807.0 51518.0 True False 94957.30227505823 86037.32352488553 77639.92564614322 70022.93762755737 64484.14122370669 65037.236272868766 66514.25776430346 68506.74289173215 69043.55631596691 60422.81765657999 1.5715470737356034 1.4239210758738285 1.2849438119125567 1.1588823617187263 1.0672150641866738 1.0763688089243928 1.1008135724875472 1.1337892794258302 1.1426735626329756 1.0 15.882805841410615 -5.257964827421982 1.1431467654097103 1.0909241446543527 1.621824127755499 0.9445268973090941 0.03992585995188882 0.1779734612311319 0.3282073690978048 0.01351490447743381 0.09325598037959372 5.521221526583066e-06 5.257964827421982 0.5308999831011463 LHGSVPNLS(ph)RYLESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LHGSVPNLSRYLESR 15 1 J3QLK7;Q9BZF2-2;Q9BZF2 J3QLK7 OSBPL7 Oxysterol-binding protein-related protein 7 1 LHGSVPNLS(0.845)RY(0.063)LES(0.092)R 90.476 0.033143 0.0 10559.0 10595.0 10977.0 12891.0 14528.0 10870.0 13220.0 10291.0 10181.0 8940.3 True False 12346.430150243794 11646.801580084342 11238.733310504324 12168.759063185882 11681.342690120611 10299.95806445864 11967.705895488416 10020.872154215805 10329.877864440305 10561.105618624146 1.1690471240502784 1.1028013543909274 1.0641625712638652 1.1522239718658522 1.1060719504140708 0.9752727068930188 1.1331868393005917 0.9488468836581222 0.9781057246718489 1.0 13.36647325468247 -7.138305836656274 0.7288576582144658 0.9759684736771586 1.1251808372129986 0.500910409846944 0.05448327252805907 0.5931495967389295 0.6393546116089438 0.04412422959513441 0.03101472442961124 7.272674715533389e-08 7.138305836656274 0.14921236353584 LHGSVPNLS(ph)RYLESR ddPTM_PC-9_Lapatinib_30min_R1 1 LHGSVPNLSRYLESR 15 1 J3QLK7;Q9BZF2-2;Q9BZF2 J3QLK7 OSBPL7 Oxysterol-binding protein-related protein 7 1 LHGSVPNLS(0.375)RY(0.25)LES(0.375)R 99.568 0.017715 0.0 19672.0 19883.0 19032.0 15816.0 14769.0 18022.0 16155.0 13290.0 18546.0 13741.0 True False 19391.473672597018 19836.962135107875 17467.262425644545 16979.161400629328 13900.316456971192 17251.241071333916 16991.426852977907 13907.501917530315 16457.154181962047 16116.113541268403 1.2032351114269222 1.2308775365916556 1.0838383820588176 1.0535518602019602 0.8625104570886003 1.0704343219696735 1.0543129278326375 0.8629563127560181 1.0211614692227344 1.0 13.976216254261768 -5.546727529644398 1.8657130830064326 0.9805212410413725 1.2226437730783617 0.6363206796197907 0.06900593046666231 0.22341861586044276 1.5228145148641585 0.020629262668491667 0.054425329178990775 2.839700058255706e-06 5.546727529644398 0.2421225320369892 LHLS(ph)PPLGR ddPTM_PC-9_AZD4547_30min_R2 1 LHLSPPLGR 9 0 Q6P0Q8;A0A669KBJ4 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 LHLS(1)PPLGR 57.885 0.04573 5551900.0 9145.5 8036.0 12946.0 17858.0 12010.0 12892.0 12490.0 14438.0 11752.0 12896.0 True False 12053.578761782674 10633.479847455019 12774.327581233863 13741.11400334965 10342.618807690198 12085.861201994252 13601.585803663904 12206.93885223404 12373.186727816495 12444.514965236907 0.9685856616713232 0.854471217010794 1.0265026493132332 1.1041904037027337 0.8310985873360075 0.9711797716307518 1.0929783797648371 0.9809091705328392 0.9942682991165455 1.0 13.603222380789733 -7.021141203143691 24.604347105520624 1.0178239246180512 0.957099413725992 0.11815036767394471 0.0780235274295536 1491.9739014753536 1736370.1858282299 0.03060186280421366 0.023972773095586247 9.524864296145327e-08 7.021141203143691 -0.0607245108920591 LHLS(ph)PPLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LHLSPPLGR 9 0 Q6P0Q8;A0A669KBJ4 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 LHLS(1)PPLGR;LHLS(1)PPLGR 63.693999999999996 0.031974 11314100.0 29228.0 28684.0 33495.0 34879.0 45698.0 33981.0 37781.0 36797.0 30779.0 25620.0 True False 34175.72312068617 31531.55795404808 34293.64783049489 32924.84270924373 36743.80494583784 32198.976539868334 34202.1101692472 35831.117739644265 31229.084646852778 30264.703192191577 1.1292271033903167 1.0418591503710288 1.133123547015085 1.0878957741683215 1.2140811265354783 1.0639118558471707 1.1300989787361104 1.1839243065462757 1.0318648905471512 1.0 14.885348582067806 -8.445999541046952 6.022136516125369 1.0003719191423603 1.1205491323921946 0.44318267439836123 0.048566909516882126 0.18261866440756422 10.406812941350156 0.04564861430924694 0.011833963082217269 3.580968155314328e-09 8.445999541046952 0.12017721324983421 LHPDGS(ph)PDVAGEK ddPTM_PC-9_AZD4547_30min_R2 3 LHPDGSPDVAGEK 13 0 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 LHPDGS(1)PDVAGEK;LHPDGS(1)PDVAGEK;LHPDGS(1)PDVAGEK 105.19 0.0012562 19307500.0 90252.0 83091.0 116755.0 139143.0 126995.0 122130.0 105183.0 112493.0 94056.0 108858.0 True False 118950.25864178149 109948.54081693458 115206.75241363815 107065.73108792026 109363.93634326513 114493.1917933258 114544.0832335295 95109.79168197566 99027.60814087039 105046.91455379629 1.1323536645225791 1.046661306369242 1.0967171468386046 1.0192182373247154 1.0410961312648361 1.0899243664571596 1.0904088303790165 0.9054030009921742 0.9426988747028519 1.0 16.680674262118316 -7.756486424722312 24.99997897157351 0.9430381935217836 1.0708752499099237 0.6978372815039997 0.03740931963175406 62.83975264093081 317187.8913188543 0.017974915921489504 0.009958116646352879 1.7519171951868916e-08 7.756486424722312 0.12783705638814002 LHPDGS(ph)PDVAGEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LHPDGSPDVAGEK 13 0 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 LHPDGS(1)PDVAGEK;LHPDGS(1)PDVAGEK;LHPDGS(1)PDVAGEK;LHPDGS(1)PDVAGEK 159.18 8.377700000000001e-05 13149900.0 133567.0 138903.0 137522.0 173780.0 186116.0 148077.0 178565.0 141486.0 154672.0 135780.0 True False 156177.2550315001 152692.37186205373 140801.046035089 164043.67000236156 149647.90584488516 140311.58144533954 161650.03050135315 137772.14241680852 156933.78538932445 160395.83916611134 0.9736989178987222 0.9519721500002276 0.8778347790510369 1.0227426774610555 0.9329911961737657 0.8747831750175772 1.0078193508121052 0.8589508501783955 0.9784155636780486 1.0 17.291277191714208 -8.511674786028214 24.554633211979063 1.0000000283781998 0.9377465318615436 0.14084740671124696 0.052359012686588054 834.5742354256909 1829054.4506323151 0.04771523043455173 0.012320019400959743 3.0784011597422007e-09 8.511674786028214 -0.06225349651665624 LHPDGS(ph)PDVAGEK ddPTM_PC-9_Lapatinib_30min_R1 4 LHPDGSPDVAGEK 13 0 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 LHPDGS(1)PDVAGEK;LHPDGS(1)PDVAGEK;LHPDGS(1)PDVAGEK;LHPDGS(1)PDVAGEK 141.82 5.4000000000000005e-05 27153400.0 166215.0 156390.0 172464.0 145361.0 142248.0 161909.0 139111.0 141760.0 156235.0 123534.0 True False 163844.74361990232 156027.88856357287 158284.67565029176 156051.33285008132 133881.25231032824 154984.52949831338 146313.48690464944 148346.687120323 138638.1690725139 144886.68730129156 1.1308474689547392 1.0768959624227807 1.092472183597787 1.0770577736074047 0.9240410889643882 1.0696947551573415 1.0098476929104663 1.023880729716985 0.9568730685671357 1.0 17.144565515523887 -6.029077126594671 20.759685638034643 1.0026150709267114 1.095589503495895 0.6042791526919871 0.03857402428620499 60.13395010396523 42932.859392818405 0.010992039033885175 0.014243573731293589 9.352395696917885e-07 6.029077126594671 0.09297443256918347 LHPPS(ph)PVPQGVCPAHR ddPTM_PC-9_AZD4547_30min_R2 3 LHPPSPVPQGVCPAHR 16 0 Q96F44-2;Q96F44-3;Q96F44 Q96F44-2 TRIM11 E3 ubiquitin-protein ligase TRIM11 1 LHPPS(1)PVPQGVCPAHR;LHPPS(1)PVPQGVCPAHR;LHPPS(1)PVPQGVCPAHR 98.572 0.0017535999999999997 16446300.0 22827.0 25179.2 22481.899999999998 22049.4 27315.2 26580.1 24471.5 28799.8 23284.5 24486.0 True False 30085.511168904195 33317.883993907366 22183.775316587493 16966.25148983413 23522.955974672725 24918.04214513865 26649.41609242286 24349.45266356626 24515.271133751103 23628.75259295835 1.2732585459407635 1.4100568306697872 0.9388466542748652 0.71803415872619 0.9955225474612166 1.054564435727535 1.1278384666131172 1.0305009783217538 1.0375186348625507 1.0 14.528255848241022 -5.263428424609561 24.99964513629044 0.9869620730116959 1.341657706450972 0.6390828560135374 0.10635099195578342 111.12696056614891 1396737.2148984368 0.03094466375140798 0.069994123598561 5.452197450933232e-06 5.263428424609561 0.3546956334392761 LHPPS(ph)PVPQGVCPAHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LHPPSPVPQGVCPAHR 16 0 Q96F44-2;Q96F44-3;Q96F44 Q96F44-2 TRIM11 E3 ubiquitin-protein ligase TRIM11 1 LHPPS(1)PVPQGVCPAHR;LHPPS(1)PVPQGVCPAHR;LHPPS(1)PVPQGVCPAHR 80.459 0.006945699999999999 14588500.0 36912.9 63448.5 51883.7 48418.7 53288.799999999996 40463.100000000006 50162.4 37743.2 41474.7 38634.5 True False 43161.52490699252 69747.24776347165 53120.804178027975 45705.95721454334 42847.24217685158 38341.14380478348 45410.65432767384 36752.48099222601 42081.18902507636 45638.62901946626 0.9457235204980154 1.5282502840679622 1.1639439071530904 1.001475245784626 0.9388371889649869 0.8401028827669171 0.9950047865878008 0.8052932741811758 0.9220519969416141 1.0 15.47796783339066 -5.7946855093205345 2.709413347400432 0.9109033331859109 1.2571327614861902 0.45969427562710763 0.14332900495923806 0.20390217051799558 3.0513610365811674 0.03976995501478856 0.0693594600395384 1.6044067877501468e-06 5.7946855093205345 0.34622942830027936 LHPPS(ph)PVPQGVCPAHR ddPTM_PC-9_Lapatinib_30min_R1 2 LHPPSPVPQGVCPAHR 16 0 Q96F44-2;Q96F44-3;Q96F44 Q96F44-2 TRIM11 E3 ubiquitin-protein ligase TRIM11 1 LHPPS(1)PVPQGVCPAHR;LHPPS(1)PVPQGVCPAHR 80.609 0.0044891 12403200.0 35861.1 62497.2 57310.5 58328.9 73725.3 74271.0 68438.0 80631.0 61475.0 68090.6 True False 35349.714137879666 62352.49157321653 52598.651914927555 62618.60188550635 69388.92280351669 71094.60246415724 71981.38477029421 84377.4106179372 54551.03813955123 79859.9694849787 0.4426462264617918 0.7807727948724642 0.6586360131883237 0.7841050064173218 0.868882410687227 0.8902407917590028 0.9013450071983008 1.0565670280378483 0.6830836336571858 1.0 16.28518490025722 -4.265305975328696 0.47772412437911843 0.9253568583934284 2.3482969953077367e-18 0.6005651109256351 0.10772430956822375 5.208983250801888 0.6346147452484737 0.06575892869238473 3.006474893916633 5.4286772783258285e-05 4.265305975328696 -0.9253568583934284 LHQLAMQQSHFPMTHGNTGFSGIES(ph)SSPEVK ddPTM_PC-9_AZD4547_30min_R2 1 LHQLAMQQSHFPMTHGNTGFSGIESSSPEVK 31 0 Q15366-2;Q15366;Q15366-6;Q15366-3;Q15366-5;H3BRU6;F8VZX2;Q15366-4;F8VRH0 Q15366-2 PCBP2 Poly(rC)-binding protein 2 1 LHQLAMQQSHFPMTHGNTGFSGIES(0.333)S(0.333)S(0.333)PEVK 73.676 1.4074e-06 34546000.0 5490.0 5281.3 14781.0 25189.0 18754.0 14868.0 11682.0 19582.0 11329.0 16361.0 True False 7235.705800906116 6988.3769435495515 14584.99428226616 19382.065216170588 16150.330817603817 13938.301609622296 12721.675368967319 16556.051849594616 11927.827811388099 15788.20636990083 0.4582981518851001 0.44263273356195987 0.9237904509578418 1.227629330531251 1.0229363893034331 0.8828299607354224 0.8057707804744908 1.0486341172457456 0.7554897327746939 1.0 13.94655966168932 -5.27717454706587 5.74870088972343 0.9654836560390515 0.44664529059059294 0.7240601634143818 0.12550086686905387 0.07932730657269112 10.104189093482095 0.03438910157988728 0.07925926396857451 5.282329072975987e-06 5.27717454706587 -0.5188383654484585 down LHQLAMQQSHFPMTHGNTGFSGIES(ph)SSPEVK ddPTM_PC-9_Lapatinib_30min_R1 1 LHQLAMQQSHFPMTHGNTGFSGIESSSPEVK 31 0 Q15366-2;Q15366;Q15366-6;Q15366-3;Q15366-5;H3BRU6;F8VZX2;Q15366-4;F8VRH0 Q15366-2 PCBP2 Poly(rC)-binding protein 2 1 LHQLAMQQSHFPMTHGNT(0.008)GFS(0.016)GIES(0.325)S(0.325)S(0.325)PEVK 53.525 0.00074321 8056800.0 20374.0 9957.2 21000.0 19373.0 27561.0 31009.0 20227.0 24189.0 33298.0 22874.0 True False 20083.463023865992 9934.144715168544 19273.461062344217 20797.755046433493 25939.916167010833 29682.81735550956 21274.2550885289 25312.909246285977 29547.628596515286 26827.74042231087 0.7486080716348327 0.370293754106364 0.7184153700218354 0.7752331996300875 0.9669064840599959 1.1064225644148662 0.7929946672227564 0.9435348951428981 1.1013834237020745 1.0 14.711437927669866 -5.890145429728509 1.8118721943371534 0.9791771844848861 0.5634137497770642 0.6547754405655024 0.1232973703457057 0.20579117257339774 1.3757029116033794 0.03886212571368108 0.07027905823352475 1.2878182350969484e-06 5.890145429728509 -0.41576343470782195 LHQLAMQQSHFPMTHGNTGFSGIESS(ph)SPEVK ddPTM_PC-9_AZD4547_30min_R2 1 LHQLAMQQSHFPMTHGNTGFSGIESSSPEVK 31 0 Q15366-2;Q15366;Q15366-6;Q15366-3;Q15366-5;H3BRU6;F8VZX2;Q15366-4;F8VRH0 Q15366-2 PCBP2 Poly(rC)-binding protein 2 1 LHQLAMQQS(0.007)HFPMT(0.024)HGNT(0.007)GFS(0.006)GIES(0.177)S(0.389)S(0.389)PEVK 52.17 0.0023889 36993000.0 10481.0 6542.2 23554.0 43404.0 33432.0 29100.0 23053.0 31512.0 18830.0 31627.0 True False 13813.73998165702 8656.838210306152 23241.658570089803 33397.878385115255 28790.54387832629 27280.37239978535 25104.67234042146 26642.544473722042 19825.3153577931 30519.748356509575 0.45261644428698833 0.28364710315377584 0.7615285125747957 1.0943038584389835 0.9433414568828035 0.8938596767285174 0.8225714067877257 0.872960817451807 0.649589738624583 1.0 14.897455446364344 -5.38019936710158 4.407874165726461 0.8922429187389566 0.37131014284158304 0.7591455474565578 0.1169755672954882 0.10154001750060863 3.15626850606402 0.03176245222484285 0.06992285589325105 4.166780594474309e-06 5.38019936710158 -0.5209327758973735 down LHQLAMQQSHFPMTHGNTGFSGIESSS(ph)PEVK ddPTM_PC-9_AZD4547_30min_R2 2 LHQLAMQQSHFPMTHGNTGFSGIESSSPEVK 31 0 Q15366-2;Q15366;Q15366-6;Q15366-3;Q15366-5;H3BRU6;F8VZX2;Q15366-4;F8VRH0 Q15366-2 PCBP2 Poly(rC)-binding protein 2 1 LHQLAMQQS(0.001)HFPMT(0.006)HGNT(0.007)GFS(0.006)GIES(0.086)S(0.234)S(0.661)PEVK;LHQLAMQQS(0.001)HFPMT(0.025)HGNT(0.031)GFS(0.031)GIES(0.056)S(0.226)S(0.629)PEVK 52.183 0.0023783000000000003 60079000.0 50794.0 44623.0 122904.0 191586.0 173629.0 140399.0 103146.0 149501.0 121871.0 163978.0 True False 66945.43541916674 59046.51209967464 121274.21265595309 147418.80767419338 149523.6104046994 131619.82833530832 112325.79417972133 126399.05564121326 128312.85225542246 158237.180131019 0.42307019983379696 0.3731519485545979 0.7664078224570173 0.9316319183148479 0.9449334870660306 0.8317882575152581 0.7098571529568244 0.7987949199837607 0.8108894012720685 1.0 17.271729096298372 -5.326815263246348 4.096723653458294 0.8483184197587863 0.39401796426963287 0.8344018168247637 0.08100263057159608 0.08287638424547579 2.7484395237116397 0.022951892833619248 0.05335113636701751 4.71177709624716e-06 5.326815263246348 -0.45430045548915343 LHQLAMQQSHFPMTHGNTGFSGIESSS(ph)PEVK ddPTM_PC-9_Lapatinib_30min_R1 1 LHQLAMQQSHFPMTHGNTGFSGIESSSPEVK 31 0 Q15366-2;Q15366;Q15366-6;Q15366-3;Q15366-5;H3BRU6;F8VZX2;Q15366-4;F8VRH0 Q15366-2 PCBP2 Poly(rC)-binding protein 2 1 LHQLAMQQSHFPMT(0.001)HGNT(0.001)GFS(0.001)GIES(0.024)S(0.405)S(0.568)PEVK 55.925 0.00064796 13644000.0 23131.0 12647.0 28033.0 21906.0 32921.0 39538.0 24487.0 26214.0 45798.0 27907.0 True False 22801.147698294117 12617.716648529364 25728.234950509323 23517.040316273793 30984.651505176273 37847.05190757965 25754.817044188803 27431.998138911935 40639.74696567984 32730.687766259918 0.6966290430902108 0.38550111560858197 0.7860584884204909 0.718501257419836 0.9466544585450621 1.1563170373276994 0.7868706343145616 0.838112487425025 1.2416404829590197 1.0 14.99835629743923 -5.9075623644729145 1.41266646262294 0.9876995333203862 0.5552635162394871 0.5589717908949575 0.15482589160017632 0.31939162550309924 1.2941821372369178 0.05349615263366185 0.10610112265131616 1.2371935168013457e-06 5.9075623644729145 -0.43243601708089907 LHQLS(ph)GSDQLESTAHSR ddPTM_PC-9_AZD4547_30min_R2 1 LHQLSGSDQLESTAHSR 17 0 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 LHQLS(0.632)GS(0.368)DQLESTAHSR 81.017 0.0046345 5518200.0 4045.6 3811.1 18838.0 32970.0 24625.0 24180.0 15545.0 23490.0 13910.0 20983.0 True False 5332.0166462924935 5042.963544877532 18588.195811469446 25369.275881422214 21206.243808440548 22668.020777553596 16928.47488534472 19860.160246500724 14645.254202172167 20248.391556728136 0.2633303801615181 0.24905501904924668 0.9180085123992459 1.2529032644567024 1.0473051031746834 1.119497354347707 0.8360404745195539 0.9808265605127331 0.7232798793495201 1.0 14.305519690742054 -5.285208292776515 4.901170437024272 0.9994247189425203 0.24754790698147613 0.820431273814432 0.13655808255035204 0.0689648292439022 4.679702316328438 0.03761499777901638 0.08807811610802667 5.1855127594617125e-06 5.285208292776515 -0.7518768119610442 down LHQLS(ph)GSDQLESTAHSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LHQLSGSDQLESTAHSR 17 0 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 LHQLS(0.742)GS(0.258)DQLESTAHSR 101.05 0.0009484999999999999 3294500.0 9027.7 8014.7 15094.0 12566.0 17816.0 14331.0 16921.0 14539.0 13535.0 10786.0 True False 10555.911304797413 8810.346448692973 15453.898204313778 11861.967759521678 14325.082693226106 13579.45713171635 15318.120382568799 14157.36665534386 13732.9237692957 12741.416418070981 0.828472358051661 0.6914730795704452 1.2128869897381047 0.9309771669261203 1.124292796278837 1.065772963236394 1.2022305746826791 1.1111297355657144 1.0778176710258427 1.0 13.637238045349358 -5.256060334571303 24.999850102783054 1.0932045347076085 0.7599726939707674 0.7058664635854996 0.08536793742672698 215.6646150985514 1002323.067251785 0.020843568227855908 0.05189808733904216 5.545486666640071e-06 5.256060334571303 -0.3332318407368411 LHQLSGS(ph)DQLESTAHSR ddPTM_PC-9_AZD4547_30min_R2 1 LHQLSGSDQLESTAHSR 17 0 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 LHQLS(0.386)GS(0.614)DQLESTAHSR 72.801 0.0099456 7902200.0 10054.0 12753.0 24364.0 31056.0 44184.0 28955.0 25760.0 32934.0 26481.0 30723.0 True False 13250.96286380876 16875.15785149253 24040.91744084521 23896.519010416996 38049.814271355826 27144.439272707394 28052.590096267602 27844.8070480313 27880.731597967013 29647.397121353395 0.44695198062648195 0.5691952579317083 0.8108947083091438 0.8060241819072084 1.2834116302220215 0.915575797821278 0.946207519717232 0.9391990444913699 0.9404107714361896 1.0 14.855617829179012 -5.3515917538654225 1.423335482987357 0.9894515402492502 0.42966426520502177 0.7476950205991044 0.11031192809155643 0.2727416359099887 0.927780823839932 0.034780861950456425 0.16021718827524792 4.4504942691261845e-06 5.3515917538654225 -0.5597872750442284 down LHQSAS(ph)SSTSSLSTR ddPTM_PC-9_Lapatinib_30min_R1 1 LHQSASSSTSSLSTR 15 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 LHQS(0.001)AS(0.498)S(0.498)S(0.001)T(0.001)S(0.001)SLSTR 56.568999999999996 0.037404 503570.0 607.99 430.65 0.0 0.0 0.0 0.0 0.0 0.0 0.0 578.78 True False 599.3199511082893 429.65285638405715 0.0 0.0 0.0 0.0 0.0 0.0 0.0 678.8213518241273 0.8828831761078197 0.6329395138050606 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 9.406888134275684 -11.151034045741534 6.943046877816905 1.00222061739382 0.15236492892775638 0.4007632752268605 0.3044855238041945 0.011480042546799076 0.0006148293366123654 0.32337274012029316 0.07832333404193824 7.062621859279838e-12 11.151034045741534 -0.8498556884660635 LHS(ph)PQTHWK ddPTM_PC-9_AZD4547_30min_R2 1 LHSPQTHWK 9 0 B8ZZS4;Q9H8Y5 B8ZZS4 ANKZF1 Ankyrin repeat and zinc finger domain-containing protein 1 1 LHS(1)PQTHWK 93.62299999999999 0.0034646 9990900.0 60431.0 48599.0 67728.0 87833.0 75816.0 80105.0 56357.0 75620.0 66225.0 82041.0 True False 79646.8009571142 64307.67634475691 66829.88246731095 67584.45885632261 65290.25707942056 75096.02168676301 61372.66382202456 63934.66657472904 69725.5182989829 79168.76956133683 1.006038130924935 0.812285914017318 0.8441445135197384 0.8536757515722264 0.8246971304617315 0.9485561301869367 0.7752130563867795 0.8075743368121313 0.8807199945802155 1.0 16.27264380878559 -3.620892257800427 13.260996650032585 0.8645784799038084 0.8691028110354422 0.0 0.07858735102602118 0.0 0.0 0.016929684015996038 0.0 0.00023939095771953605 3.620892257800427 0.004524331131633752 LHS(ph)PQTHWK ddPTM_PC-9_Lapatinib_30min_R1 1 LHSPQTHWK 9 0 B8ZZS4;Q9H8Y5 B8ZZS4 ANKZF1 Ankyrin repeat and zinc finger domain-containing protein 1 1 LHS(0.996)PQT(0.004)HWK 66.663 0.041277999999999995 8626500.0 47314.0 44820.0 51835.0 42305.0 42361.0 37972.0 39435.0 43326.0 45451.0 34947.0 True False 46639.293683675045 44716.22204373258 47573.32638888634 45416.25082534297 39869.409264930364 36348.02607705532 41476.75134306307 45339.08412933919 40331.829759751796 40987.54238604954 1.1378894895525409 1.0909710473139302 1.160677699111775 1.1080501094108237 0.9727201716417195 0.886806672493413 1.0119355523296765 1.106167422830668 0.9840021482595422 1.0 15.322897868088782 -6.199327485157666 5.497011005545054 0.9945646303295624 1.126300716377807 0.5977252664995927 0.05265427880537048 0.17292381831604484 10.720506527959802 0.017346507679020663 0.02240315166414183 6.319351531038021e-07 6.199327485157666 0.1317360860482445 LHS(ph)SNPNLSTLDFGEEK ddPTM_PC-9_AZD4547_30min_R2 4 LHSSNPNLSTLDFGEEK 17 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 LHS(0.498)S(0.498)NPNLS(0.003)T(0.001)LDFGEEK;LHS(0.499)S(0.499)NPNLS(0.001)TLDFGEEK;LHS(0.5)S(0.5)NPNLSTLDFGEEK;LHS(0.5)S(0.5)NPNLSTLDFGEEK 99.93 0.0006854 394116800.0 187387.0 197684.0 237353.0 240940.0 227428.0 246061.0 225598.0 272817.0 233934.0 229707.0 True False 246972.1681082682 261581.4870786833 234205.54413630493 185395.0054858925 195853.54789303624 230674.7667719447 245675.78495876477 230659.40136098742 246299.27365427336 221665.02784736955 1.1141683941154858 1.1800755835006989 1.0565741759569323 0.8363746292606371 0.8835563724012154 1.0406457392583324 1.1083200058420049 1.040576421102435 1.1111327575943375 1.0 17.758021648200703 -5.515799558130125 24.943753482864288 1.0010717407061103 1.1399227416445785 0.3180626437766503 0.08363852282779236 396.5406818405919 1397222.8871641476 0.02546757543728911 0.04651179012456156 3.049302022873183e-06 5.515799558130125 0.13885100093846825 LHS(ph)SNPNLSTLDFGEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LHSSNPNLSTLDFGEEK 17 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 LHS(0.5)S(0.5)NPNLSTLDFGEEK;LHS(0.5)S(0.5)NPNLSTLDFGEEK;LHS(0.5)S(0.5)NPNLSTLDFGEEK;LHS(0.5)S(0.5)NPNLSTLDFGEEK;LHS(0.5)S(0.5)NPNLSTLDFGEEK 122.46 3.2824e-05 575759300.0 1032780.0 1081866.0 1067106.0 1155405.0 1253193.0 1040947.0 1268460.0 970016.0 908253.0 971345.0 True False 1207609.2556651952 1189266.5066766911 1092549.8540620396 1090671.4037235503 1007638.8277712225 986357.9068375365 1148302.2859448735 944554.1078169087 921534.4818791394 1147442.1593372093 1.052435842485289 1.0364500702707669 0.952161157032197 0.9505240807550149 0.878160889916455 0.8596144902042653 1.0007496034555337 0.8231823278678433 0.8031206404438201 1.0 20.129990000923577 -5.416357882651417 1.0376326271390164 0.8881081964232649 1.0759721602703054 0.45665944076203124 0.06253411804539022 0.7259038866745228 1.2055083476721782 0.022411710847672277 0.12036353497653235 3.8339117976472155e-06 5.416357882651417 0.18786396384704052 LHS(ph)SNPNLSTLDFGEEK ddPTM_PC-9_Lapatinib_30min_R1 4 LHSSNPNLSTLDFGEEK 17 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 LHS(0.5)S(0.5)NPNLSTLDFGEEK;LHS(0.5)S(0.5)NPNLSTLDFGEEK;LHS(0.5)S(0.5)NPNLSTLDFGEEK;LHS(0.5)S(0.5)NPNLSTLDFGEEK 93.76799999999999 0.0010316 581492000.0 251074.0 284946.0 310517.0 264271.0 293858.0 281076.0 258961.0 257827.0 280178.0 203262.0 True False 247493.6387186673 284286.22504403023 284987.49089028355 283706.3709222121 276573.85018705693 269055.0347001579 272368.7334740957 269806.58366373845 248621.40323486243 238395.56587040945 1.0381637670777968 1.1924979561011075 1.1954395621821305 1.1900656368601812 1.1601467887091532 1.1286075465280037 1.1425075482408673 1.131760075648403 1.0428944109221046 1.0 17.86299787652773 -8.32542434717995 1.7071189650964507 0.9982875143879714 1.1553805201716625 0.5838301330784893 0.04336224452635613 0.24204034224659154 1.386288254299057 0.04120750196959565 0.01215095190609244 4.726891707887775e-09 8.32542434717995 0.15709300578369112 LHS(ph)SNPNLSTLDFGEEKNYSDGSETSSEFSK ddPTM_PC-9_AZD4547_30min_R2 3 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSK 31 1 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 LHS(0.493)S(0.493)NPNLS(0.006)T(0.006)LDFGEEKNYSDGSETSSEFSK;LHS(0.464)S(0.464)NPNLS(0.036)T(0.036)LDFGEEKNYSDGSETSSEFSK;LHS(0.499)S(0.499)NPNLS(0.001)T(0.001)LDFGEEKNYSDGSETSSEFSK 93.529 1.2578e-10 27660200.0 81055.0 37497.9 101380.0 269359.0 174604.0 93678.0 73439.0 98405.0 73527.0 137027.0 True False 106828.803951265 49618.36286359924 100035.63495948483 207262.44410506537 150363.24848442432 87820.29985110268 79974.9287298058 83198.76837194152 77413.48711165448 132229.726437773 0.8079030852532119 0.37524363242897224 0.7565290926209498 1.567442130363951 1.137136501263087 0.6641494482137548 0.6048180759675232 0.6291986727439436 0.5854469278364959 1.0 17.012687018630345 -6.8030486880825 23.996810902034575 0.6678029361972805 0.9239988194210843 0.12359654434433609 0.3040907326541905 222.60093275878623 128375.69872979425 0.1199856804373328 0.10581884484978234 1.5738064175730608e-07 6.8030486880825 0.2561958832238038 LHS(ph)SNPNLSTLDFGEEKNYSDGSETSSEFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSK 31 1 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 LHS(0.499)S(0.499)NPNLS(0.001)T(0.001)LDFGEEKNYSDGSETSSEFSK;LHS(0.5)S(0.5)NPNLS(0.001)TLDFGEEKNYSDGSETSSEFSK 85.395 3.2456999999999997e-09 28631000.0 81411.0 28581.0 60199.0 128355.0 131328.0 167640.0 95433.0 187293.0 148683.0 100980.0 True False 95192.27435945602 31418.332794751375 61634.372465978806 121163.68548252477 105595.22114593611 158848.66328664654 86392.89536491256 182376.75720333683 150857.20759439937 119286.87464275995 0.7980113037963112 0.26338465894795987 0.5166903119103529 1.0157335905176952 0.8852207878039594 1.3316524870180908 0.7242447723074462 1.5288920742497305 1.264658899364965 1.0 16.864075783777267 -5.91330042916644 1.8593493772337342 1.149577432498103 0.4842211848255465 0.530987011885674 0.2489225808374835 0.2543071171636556 1.7867107687462718 0.07877779942431534 0.1381024943473698 1.2209547557574858e-06 5.91330042916644 -0.6653562476725565 LHS(ph)SNPNLSTLDFGEEKNYSDGSETSSEFSK ddPTM_PC-9_Lapatinib_30min_R1 2 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSK 31 1 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 LHS(0.5)S(0.5)NPNLSTLDFGEEKNYSDGSETSSEFSK;LHS(0.5)S(0.5)NPNLS(0.001)TLDFGEEKNYSDGSETSSEFSK 113.15 1.2204999999999998e-16 24859000.0 340700.0 71414.0 153314.0 111567.0 89439.0 92769.0 43127.0 38219.0 149144.0 51457.0 True False 335841.55552327255 71248.64527066312 140709.11472915416 119772.00935660175 84178.37386383947 88801.48612510132 45359.90503796837 39994.7942653191 132345.83216405418 60351.2738878574 5.564779894245835 1.180565722656573 2.3315019827189536 1.9845812961489073 1.3948069102941678 1.471410301795934 0.7515981373028602 0.6627000838397547 2.1929252464492217 1.0 15.88109660309475 -4.759130852809727 24.999934450372244 1.4533394245882696 5.564785224323044 0.836017081389345 0.547868858918181 24.68808227128194 267296.8624875209 0.14343420424790077 0.9325685855738456 1.7412821465066023e-05 4.759130852809727 4.111445799734774 LHS(ph)SSLELGPRPLEQENER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LHSSSLELGPRPLEQENER 19 1 Q86X02 Q86X02 CDR2L Cerebellar degeneration-related protein 2-like 1 LHS(0.493)S(0.416)S(0.09)LELGPRPLEQENER 50.077 0.025877999999999998 2817600.0 2642.5 3279.2 4322.1 5288.9 4362.5 4715.2 4662.2 2961.5 3531.8 3529.6 True False 3089.8230582459723 3604.7373045221866 4425.155255655531 4992.580079845151 3507.6994414682804 4467.926611364796 4220.5626645950115 2883.7637629686224 3583.4458934908457 4169.488539701774 0.7410556543865627 0.8645514360329716 1.0613184839145866 1.1974082749732775 0.8412781107486078 1.0715766619385811 1.012249494010335 0.6916348937068636 0.8594449557468155 1.0 12.025654707542818 -7.729822209094688 24.991529761951647 0.8316546168857682 0.9770941630334049 0.12441312490275847 0.14189397342639473 336.5260110423823 266004.2514622777 0.06875336664798862 0.03969031732083767 1.8628495915080003e-08 7.729822209094688 0.14543954614763666 LHS(ph)SSLELGPRPLEQENER ddPTM_PC-9_Lapatinib_30min_R1 1 LHSSSLELGPRPLEQENER 19 1 Q86X02 Q86X02 CDR2L Cerebellar degeneration-related protein 2-like 1 LHS(0.449)S(0.449)S(0.103)LELGPRPLEQENER 49.223 0.028312 2299200.0 15948.0 12814.0 17498.0 13709.0 12219.0 17743.0 12615.0 13188.0 16975.0 11866.0 True False 15720.578595494979 12784.329970289817 16059.381984233298 14717.205591883381 11500.302443478293 16984.173250953132 13268.142974330949 13800.762625161005 15063.096745325445 13917.022289548866 1.1295935487076507 0.9186110149360286 1.1539380802956147 1.0574967321088091 0.8263479215747586 1.220388449309848 0.9533751328612012 0.9916462256099735 1.082350551140328 1.0 13.764562942197985 -6.042668411477024 24.97913069194531 1.0123445458326068 1.0613732871212567 0.051913143550931906 0.10974486872921371 1751.7679414972908 1025525.2488966273 0.03131052924608722 0.04042509317113389 9.064244015768864e-07 6.042668411477024 0.04902874128864987 LHS(ph)YSSPSTK ddPTM_PC-9_Lapatinib_30min_R1 1 LHSYSSPSTK 10 0 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 LHS(0.761)YS(0.151)S(0.072)PS(0.013)T(0.004)K 121.9 0.00058386 34450000.0 67484.0 44939.0 71448.0 54980.0 50455.0 52076.0 46805.0 40696.0 59669.0 38672.0 True False 66521.66578495012 44834.94650654395 65573.82123725572 59023.41260790345 47487.336098346605 49848.83087508518 49228.33388137616 42586.88472805218 52948.44887757434 45356.40367279903 1.4666433049859338 0.9885031192063447 1.4457456043099246 1.3013247927172131 1.0469819529987456 1.0990472532763953 1.0853667816458559 0.9389387446869432 1.1673864016985187 1.0 15.469018632503575 -6.261866282258256 24.965562893799106 1.056825803085315 1.288635663817022 0.44393543597324914 0.13366193595657172 36.97100814398605 2162080.565999364 0.038731681878970116 0.04668385762627021 5.471844131140824e-07 6.261866282258256 0.23180986073170695 LHSS(ph)NPNLSTLDFGEEK ddPTM_PC-9_AZD4547_30min_R2 4 LHSSNPNLSTLDFGEEK 17 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 LHS(0.026)S(0.974)NPNLSTLDFGEEK;LHS(0.008)S(0.992)NPNLSTLDFGEEK;LHS(0.228)S(0.772)NPNLSTLDFGEEK;LHS(0.172)S(0.826)NPNLS(0.001)T(0.001)LDFGEEK 310.98 1.3245999999999996e-129 535481000.0 1690585.0 1891603.0 1982682.0 2146720.0 2142029.0 2308552.0 1994259.0 2546016.0 2078852.0 2045455.0 True False 2228155.86364752 2503026.677437216 1956390.341218594 1651826.8704933806 1844645.2474619336 2164197.878497231 2171744.187608407 2152587.728827362 2188735.872659529 1973844.2430380478 1.1288407742943525 1.2680973619198421 0.9911574067300317 0.8368577593290577 0.9345444829135773 1.0964380224683785 1.1002611757581038 1.0905560235665812 1.108869598186091 1.0 20.91257671987718 -5.269714720701329 24.848538528486788 1.0190968123840698 1.1984690708995633 0.3988770976805126 0.08771349086224775 561.1251368397698 1684906.882628927 0.026051043800387964 0.05574612160060814 5.373846776293218e-06 5.269714720701329 0.17937225851549354 LHSS(ph)NPNLSTLDFGEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LHSSNPNLSTLDFGEEK 17 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 LHSS(1)NPNLSTLDFGEEK;LHS(0.026)S(0.974)NPNLSTLDFGEEK 310.98 1.3163999999999998e-129 28486000.0 85080.5 109533.0 104380.0 108913.0 111722.0 85399.0 108371.0 80121.0 82118.0 81611.0 True False 99482.94823352773 120406.71236162129 106868.8150633544 102810.95771071038 89830.87610308774 80920.52610365248 98105.31434190416 78017.90864521668 83318.82039800684 96406.4282676795 1.031911979534249 1.248949001899575 1.1085237466388167 1.0664325974741875 0.9317934261983624 0.8393685727985972 1.0176221244241885 0.8092604408970971 0.8642454854427968 1.0 16.55684172642694 -6.141706839011543 2.160138735005074 0.898836452454736 1.1420923676933705 0.623854790067387 0.07856314633426156 0.19091180813156983 1.751086024980253 0.024972453385239225 0.03507796883828503 7.215944113381971e-07 6.141706839011543 0.24325591523863455 LHSS(ph)NPNLSTLDFGEEK ddPTM_PC-9_Lapatinib_30min_R1 2 LHSSNPNLSTLDFGEEK 17 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 LHS(0.141)S(0.567)NPNLS(0.146)T(0.146)LDFGEEK;LHS(0.026)S(0.974)NPNLSTLDFGEEK 221.47 4.7753e-23 101881000.0 51402.0 69317.0 66669.0 59435.0 71525.0 62353.0 59436.0 67014.0 57894.0 47990.0 True False 50668.99805402767 69156.50074532375 61187.73216978227 63806.04816934778 67318.04012356051 59686.307541942224 62513.30525741847 70127.71508663485 51373.36806915295 56285.00755734447 0.9002219285909292 1.2286842224346421 1.0871053380856845 1.133624226741743 1.1960208063395092 1.060429946307326 1.1106564246922854 1.2459395162235185 0.9127362738081286 1.0 15.780463067341548 -8.279267713114956 24.953733975220768 0.9563681094852859 1.1234856102642958 0.32167067250823567 0.09515468949490424 1010.2142533158316 1413949.8699336713 0.08455354758549526 0.02201410738025196 5.256931123151516e-09 8.279267713114956 0.1671175007790099 LHSYS(ph)SPSTK ddPTM_PC-9_AZD4547_30min_R2 3 LHSYSSPSTK 10 0 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 LHSYS(0.658)S(0.268)PS(0.067)T(0.007)K;LHSYS(0.577)S(0.211)PS(0.211)TK;LHS(0.001)YS(0.752)S(0.243)PS(0.003)TK 161.93 0.00012795 91595700.0 75422.0 60391.0 112334.0 163431.0 131012.0 128847.0 93074.0 127840.0 105873.0 112261.0 True False 99404.62712494368 79911.20973962864 110844.37776226827 125754.50793377947 112823.24523173278 120790.1767214823 101357.40569177047 108085.26547095182 111469.23063598653 108330.77655958895 0.9176028297947693 0.7376593455477751 1.023203020254329 1.1608382393954901 1.0414699203201288 1.1150125620583904 0.9356289035370972 0.997733690310047 1.0289710290655143 1.0 16.725083642426007 -5.334613469892502 7.325974781453162 1.0420919427435462 0.8283622287500129 0.5803919772042614 0.0714840442861295 0.16681090610163896 14.618232465736392 0.01897905397207879 0.039893286110547765 4.627927322334308e-06 5.334613469892502 -0.21372971399353335 LHSYS(ph)SPSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LHSYSSPSTK 10 0 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 LHSYS(0.67)S(0.311)PS(0.009)T(0.009)K;LHS(0.019)YS(0.668)S(0.311)PS(0.001)TK;LHS(0.14)YS(0.63)S(0.215)PS(0.011)T(0.004)K;LHS(0.01)YS(0.59)S(0.361)PS(0.037)T(0.002)K 154.15 0.00021284 78069000.0 94895.0 86773.0 105759.0 135951.0 150865.0 129938.0 134192.0 122274.0 112057.0 83411.0 True False 110958.84923831644 95387.24997722144 108280.69565324103 128334.1062290889 121304.0862434644 123123.82253722407 121480.36229405335 119064.43706001209 113695.62163398376 98532.75401888743 1.126111315401243 0.9680765642553436 1.0989309771295446 1.3024512255537781 1.231104189173602 1.249572528071456 1.2328931988521012 1.208374192374538 1.1538865706746593 1.0 16.5883157610292 -5.562987874473411 7.777427533418867 1.210312553139832 1.0436093266169655 0.3451314751134862 0.08421260754738152 0.18788379567373142 30.97008332881584 0.021451724411296173 0.03752996341672532 2.735345096230951e-06 5.562987874473411 -0.1667032265228665 LHSYS(ph)SPSTK ddPTM_PC-9_Lapatinib_30min_R1 3 LHSYSSPSTK 10 0 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 LHSYS(0.948)S(0.052)PSTK;LHSYS(0.553)S(0.222)PS(0.222)T(0.002)K;LHSYS(0.757)S(0.222)PS(0.021)T(0.001)K 169.82 0.00016686 50708600.0 206725.0 156188.0 204981.0 165312.0 174187.0 176295.0 141723.0 144227.0 188811.0 120596.0 True False 203777.0635912777 155826.35628216196 188128.25342954177 177469.5959446661 163941.66312481824 168755.27381371724 149060.7234840353 150928.31294654962 167545.11691202616 141440.8579159307 1.4407227628129788 1.1017068093208375 1.3300842217837863 1.254726523577438 1.1590827823051066 1.1931154568789566 1.0538731571653337 1.0670771880941081 1.1845595352059533 1.0 17.109839405037455 -1.5228787452805552 0.14045527951549394 0.963466634656585 2.275893077008883 0.5430108855358576 0.0865405247138811 59.60928072041979 0.559374703880329 0.36156334817904207 15.709783350707472 0.029999999999984966 1.5228787452805552 1.3124264423522982 LHTDDELNWLDHGR ddPTM_PC-9_AZD4547_30min_R2 2 LHTDDELNWLDHGR 14 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 ; 176.99 3.9616e-05 12403400.0 19407.7 22776.0 31595.0 36073.0 36960.0 32641.0 28305.0 34594.0 27124.0 27202.0 False True 25578.944894762404 30137.896591044766 31176.02965619372 27756.9271722943 31828.741976039106 30599.953110013546 30824.09016594932 29248.292191036446 28557.719265256517 26249.666259644408 0.9744483850481118 1.1481249434922542 1.1876733725991397 1.0574201933746914 1.2125389199698828 1.1657273203910086 1.1742659834627125 1.1142348211871194 1.0879269466812405 1.0 14.680011459904714 -8.618137804838632 1.8628855505478394 1.0006178662907168 1.1355807541713063 0.2606234759227446 0.06600900158823246 0.6154549119070015 4.626316882961443 0.06246725797866751 0.017576662245195124 2.4091408692464597e-09 8.618137804838632 0.13496288788058952 LHTDDELNWLDHGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LHTDDELNWLDHGR 14 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 ; 143.94 1.1749e-05 6990600.0 23881.8 28225.0 28680.0 26514.3 30626.0 25061.0 29812.0 23520.2 28634.0 23639.1 False True 27924.51705294935 31026.991467473417 29363.839969505698 25028.789731520403 24625.05515058054 23746.75704263091 26987.991539810933 22902.819671711844 29052.718079794096 27924.681702987345 0.9999941037810298 1.1110956177578988 1.0515371412940544 0.8962963301688361 0.8818383468967593 0.850385952298626 0.9664565500463267 0.8201640367940786 1.0403956753672174 1.0 14.769253215920035 -5.7497120307240746 12.235174483237097 0.9118888205909178 1.0599567793393068 0.43257788163084576 0.06846818021575478 0.4222343210184438 432.5727634868692 0.017555388175689354 0.029380008491489994 1.7794589314688396e-06 5.7497120307240746 0.14806795874838896 LHTDDELNWLDHGR ddPTM_PC-9_Lapatinib_30min_R1 2 LHTDDELNWLDHGR 14 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 ; 183.06 3.6808999999999998e-06 6109100.0 18313.0 16910.5 18879.0 14567.8 19194.6 18420.0 16286.8 17242.1 19092.1 14010.4 False True 18051.853261807093 16871.344776228034 17326.841495047454 15639.164608756204 18065.611366035555 17632.219539117228 17130.050812075573 18043.230911380684 16941.746649274108 16432.07897231547 1.0985739109592034 1.0267322111007762 1.0544521800460835 0.951745949803725 1.0994111820222041 1.0730364410263447 1.0424761736440067 1.0980491842681415 1.031016627769214 1.0 14.00422739990474 -5.541948092078585 24.999278701189244 1.0463991688688168 1.0571379550006024 0.025065620268964084 0.044936752018320696 1796.753094730998 2355471.5632916004 0.012300217973176993 0.021307646699272483 2.871123725133355e-06 5.541948092078585 0.010738786131785583 LHVAILER ddPTM_PC-9_AZD4547_30min_R2 1 LHVAILER 8 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 98.458 0.0057255000000000006 0.0 10043.0 8356.3 10384.0 17250.0 12271.0 13217.0 9116.8 12575.0 9589.0 11720.0 False True 13236.465092622984 11057.310558647145 10246.301375214933 13273.279009843282 10567.383462878137 12390.538900617285 9928.17753841819 10631.822694752946 10095.85496366851 11309.686367290364 1.1703653543307098 0.9776849860865165 0.905975731108607 1.1736204328558553 0.9343657392163324 1.0955687450761622 0.8778472908967887 0.9400634420333775 0.8926732922380172 1.0 13.465271301571375 -7.266439124903149 24.99899688476231 0.9226512922422045 1.0347449937507367 0.2806167785729218 0.08971301588129021 585.7531794992668 2928782.4052537335 0.035412956388536594 0.02470712116330483 5.414531380991855e-08 7.266439124903149 0.11209370150853215 LHVAILER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LHVAILER 8 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 107.01 0.0027046999999999996 0.0 11250.0 11314.0 10928.0 11149.0 14330.0 14097.0 12929.0 11148.0 12040.0 9969.8 False True 13154.402802371676 12437.179148378891 11188.564964670783 10524.357675545683 11522.139368765726 13357.728503649812 11704.271522145973 10855.376812282364 12216.062222557843 11777.245819106627 1.1169337045704557 1.0560346060028425 0.9500154056833213 0.8936178999059067 0.9783390400218162 1.1341979872729764 0.9938037892660553 0.9217245677823347 1.037259679401385 1.0 13.523714575111088 -5.01055111139732 3.8948327976200865 0.987695094517277 1.1099585609655698 0.30333483173827136 0.06245489741357714 0.27397509420962507 9.282188323001156 0.017339112935658475 0.06883663340018405 9.759979120952634e-06 5.01055111139732 0.12226346644829278 LHVGNIS(ph)PTCTNK ddPTM_PC-9_AZD4547_30min_R2 3 LHVGNISPTCTNK 13 0 D6R9K7;J3QRR5;E9PB51;Q9BWF3-3;Q9BWF3-4;Q9BWF3-2;Q9BWF3 D6R9K7 RBM4 RNA-binding protein 4 1 LHVGNIS(0.775)PT(0.224)CT(0.001)NK;LHVGNIS(0.967)PT(0.033)CT(0.001)NK;LHVGNIS(0.948)PT(0.051)CTNK 105.63 0.00068448 143659000.0 171648.0 161739.0 231657.0 299062.0 262066.0 226272.0 198728.0 244060.0 168466.0 204110.0 True False 226228.49349980603 214017.96877146955 228585.07681800486 230117.87636184067 225682.6594884382 212123.1760702488 216414.40701285156 206346.13494086705 177370.76882984472 196964.17102624915 1.148576882389726 1.086583248396723 1.1605414102828968 1.1683235339851386 1.1458056473548266 1.076963261719206 1.0987501223459077 1.04763284543445 0.9005230134276896 1.0 17.587573693032915 -7.889876935988451 1.8362220624317844 0.9510780466243498 1.1316012720169246 0.774550878141303 0.03776832406898417 0.16448884958694415 1.0364545702417878 0.0305625033186918 0.011031991041281507 1.2886146487146373e-08 7.889876935988451 0.18052322539257482 LHVGNIS(ph)PTCTNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LHVGNISPTCTNK 13 0 D6R9K7;J3QRR5;E9PB51;Q9BWF3-3;Q9BWF3-4;Q9BWF3-2;Q9BWF3 D6R9K7 RBM4 RNA-binding protein 4 1 LHVGNIS(0.499)PT(0.499)CT(0.001)NK;LHVGNIS(0.82)PT(0.18)CTNK;LHVGNIS(0.485)PT(0.485)CT(0.029)NK;LHVGNIS(0.809)PT(0.191)CTNK 150.01 7.0915e-05 209606000.0 396603.0 396253.0 408323.0 460018.0 538114.0 469394.0 494617.0 463848.0 379316.0 342172.0 True False 463740.05463369115 435590.37909515365 418058.96889360005 434244.68285847915 432674.42458367057 444778.15231908945 447763.29704302497 451672.4814875802 384862.7789046303 404205.07496793754 1.1472890454690012 1.077646981868562 1.0342744185652826 1.0743177405502007 1.0704329346136767 1.1003774565531377 1.1077626798192541 1.1174339696833542 0.952147320107642 1.0 18.624727909922676 -8.263005046643437 24.999120925246356 0.9760736497885647 1.0884472640407534 0.6891162848382248 0.030884372812878647 84.43788316913653 1348160.8267152489 0.026295788680902384 0.008155615648008334 5.457515192438834e-09 8.263005046643437 0.11237361425218872 LHVGNIS(ph)PTCTNK ddPTM_PC-9_Lapatinib_30min_R1 2 LHVGNISPTCTNK 13 0 D6R9K7;J3QRR5;E9PB51;Q9BWF3-3;Q9BWF3-4;Q9BWF3-2;Q9BWF3 D6R9K7 RBM4 RNA-binding protein 4 1 LHVGNIS(0.912)PT(0.088)CTNK;LHVGNIS(0.97)PT(0.03)CTNK 135.61 2.9310999999999998e-05 103677000.0 367070.0 319600.0 361870.0 287580.0 334220.0 315630.0 287480.0 285623.0 310470.0 265578.0 True False 361835.51448760665 318859.9858361652 332118.4454585952 308729.59253875684 314561.8367018019 302131.2406694663 302364.3077495567 298894.0872980254 275501.599205961 311482.8034395593 1.1616548666315631 1.0236840760232768 1.0662496991524608 0.9911609537656653 1.009885082669869 0.9699772742930652 0.9707255245255556 0.9595845549015143 0.8844841389756524 1.0 18.248792990567942 -1.5228787452803376 0.36842949579282036 0.9473907111966439 3.534606463966356 0.7262477858324413 0.03619405914208004 33.18782127201364 0.45930047505859045 0.02773403605894636 60.68031176520261 0.029999999999999995 1.5228787452803376 2.5872157527697124 LHVGNIS(ph)PTCTNQELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LHVGNISPTCTNQELR 16 0 E9PLB0;E9PM61;U3KQD5;Q9BQ04 E9PLB0 RBM4B RNA-binding protein 4B 1 LHVGNIS(0.998)PT(0.002)CTNQELR;LHVGNIS(0.934)PT(0.057)CT(0.01)NQELR 64.331 0.017221 10256300.0 34104.0 36806.0 40677.0 42306.0 45247.0 36690.0 42261.0 41782.0 39383.0 32349.0 True False 39877.13361529635 40459.856437620045 41646.89394838157 39935.73197790257 36381.17515830725 34765.911810946396 38257.73213685598 40685.26677168837 39958.901869684 38213.61762545689 1.0435320206043843 1.0587811087183425 1.0898443156200297 1.0450654625093243 0.9520473961635886 0.9097780836061508 1.0011544186114874 1.0646798000246105 1.045671788034652 1.0 15.22179922147034 -6.055723021387476 7.66017805056062 0.9949507850778427 1.0642127208368544 0.36134369718685966 0.0420831824980635 0.35968741435869866 44.66776394291015 0.014333643729299645 0.018683207983347227 8.795833070375965e-07 6.055723021387476 0.06926193575901163 LHVGNIS(ph)PTCTNQELR ddPTM_PC-9_Lapatinib_30min_R1 2 LHVGNISPTCTNQELR 16 0 E9PLB0;E9PM61;U3KQD5;Q9BQ04 E9PLB0 RBM4B RNA-binding protein 4B 1 LHVGNIS(0.989)PT(0.009)CT(0.001)NQELR;LHVGNIS(0.992)PT(0.007)CT(0.002)NQELR 63.044 0.019839 17109000.0 90170.0 106225.0 87818.0 74289.0 97046.0 88632.0 89722.0 100638.0 93997.0 82835.0 True False 88884.15926484708 105979.04253894478 80597.94302728323 79752.46088083908 91337.94507977704 84841.41597128336 94367.36614688234 105314.00887708146 83410.0680277088 97152.91937930034 0.9148892265175202 1.0908477399962204 0.8295987762613302 0.820896185007811 0.9401461702162472 0.8732770617015541 0.9713281571957426 1.084002514282859 0.8585441236414392 1.0 16.56796972801841 -7.434449368195525 7.175826077909927 0.9879476049421538 0.9135758468468304 0.12316777656744782 0.086907087921475 0.5630111321555296 39.57795898797085 0.03751477891996628 0.02509665066398995 3.67748264456842e-08 7.434449368195525 -0.07437175809532348 LHVGNISPT(ph)CTNK ddPTM_PC-9_AZD4547_30min_R2 1 LHVGNISPTCTNK 13 0 D6R9K7;J3QRR5;E9PB51;Q9BWF3-3;Q9BWF3-4;Q9BWF3-2;Q9BWF3 D6R9K7 RBM4 RNA-binding protein 4 1 LHVGNIS(0.22)PT(0.779)CT(0.001)NK 87.088 0.015252000000000002 131000000.0 84448.0 75153.0 95031.0 137570.0 117210.0 92620.0 92194.0 103050.0 72563.0 88467.0 True False 111300.70737248103 99444.73755298504 93770.82684784767 105855.36193531242 100937.41469187073 86828.45675835448 100399.08739655638 87125.99035342265 76398.53203969946 85369.79725725898 1.3037480578415823 1.1648702556164179 1.0984075148412555 1.239962672235485 1.1823550943631653 1.0170863648264254 1.1760492659248931 1.0205715973633092 0.8949128906734438 1.0 16.38143813260234 -7.4649495132524155 0.757544155375289 0.9489767392833147 1.1992479033610697 0.5925135467055436 0.07611167944856792 0.49367339484756484 0.5387958351735141 0.06730199279710303 0.03664710408997368 3.428076356289195e-08 7.4649495132524155 0.25027116407775496 LHVGNISPT(ph)CTNK ddPTM_PC-9_Lapatinib_30min_R1 2 LHVGNISPTCTNK 13 0 D6R9K7;J3QRR5;E9PB51;Q9BWF3-3;Q9BWF3-4;Q9BWF3-2;Q9BWF3 D6R9K7 RBM4 RNA-binding protein 4 1 LHVGNIS(0.147)PT(0.845)CT(0.008)NK;LHVGNIS(0.123)PT(0.819)CT(0.057)NK 83.751 0.018961000000000002 72922000.0 161401.0 142170.0 163762.0 143441.0 166086.0 140265.0 141916.0 145211.0 177416.0 108009.0 True False 159099.39214268178 141840.814099899 150298.12049960095 153990.12964514867 156317.14801763935 134266.19292368507 149263.71607967906 151958.033178818 157433.54180669587 126678.21173705373 1.2559333602918612 1.1196938459655423 1.186455969330978 1.2156007535438402 1.233970276925816 1.0598996550597173 1.1782903629039705 1.1995593488029155 1.2427831088544339 1.0 16.950808881141207 LHYTPPLQS(ph)PIIDNDPLLGQSPWR ddPTM_PC-9_AZD4547_30min_R2 1 LHYTPPLQSPIIDNDPLLGQSPWR 24 0 H0Y322;Q5TKA1;Q5TKA1-2;C9J5J4;H7C4T7;Q5TKA1-3 H0Y322 LIN9 Protein lin-9 homolog 1 LHYTPPLQS(1)PIIDNDPLLGQSPWR 104.5 9.5514e-07 8988500.0 4304.1 5512.8 18691.0 34559.0 31485.0 25060.0 15148.0 34579.0 11546.0 26781.0 True False 5672.714269158471 7294.704791320313 18443.145127517557 26591.95648122748 27113.85122065993 23492.994238440595 16496.14265443562 29235.61009637073 12156.29798837382 25843.40534150197 0.21950335856276068 0.282265618440219 0.7136499576508858 1.028964880201891 1.0491593836945996 0.9090518036612286 0.6383114932591503 1.1312599756124713 0.47038297885813063 1.0 14.657508563575211 -5.332904682245798 3.012454594230425 0.8915797163371486 0.22806876873026394 0.6390219542842723 0.1892639817871128 0.15118388762068408 2.653639842989208 0.049505036129316136 0.13031862306581252 4.646172369419868e-06 5.332904682245798 -0.6635109476068847 LIAPVAEEEATVPNNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LIAPVAEEEATVPNNK 16 0 A0A5F9ZHM4;P07195;A0A3B3IS95;A8MW50;C9J7H8;F5H793 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain;L-lactate dehydrogenase 0 ; 166.29 0.00023094 8450200.0 92379.0 104238.0 86526.0 112490.0 128131.0 99722.0 97235.0 110072.0 101583.0 86239.0 False True 108016.9401315818 114586.05975505708 88589.10799168254 106187.5499975006 103024.65034607956 94492.40276945205 88024.19687956237 107182.72663092405 103068.45919884472 101873.44803245156 1.0603051356146622 1.1247882737664474 0.8695995836271555 1.0423476582796607 1.0113003175593045 0.9275469182053375 0.86405435940013 1.05211641208788 1.0117303496590446 1.0 16.636418555543074 -5.237866248903578 24.982335513111902 0.9726232944987923 1.0925467226954928 0.3579639045525087 0.0643952072391681 875.3004421038688 927622.728905946 0.016651888286484624 0.04400101891246825 5.7827411296036e-06 5.237866248903578 0.11992342819670054 LIAPVAEEEATVPNNK ddPTM_PC-9_Lapatinib_30min_R1 2 LIAPVAEEEATVPNNK 16 0 A0A5F9ZHM4;P07195;A0A3B3IS95;A8MW50;C9J7H8;F5H793 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain;L-lactate dehydrogenase 0 ; 230.59 1.6583e-28 40492000.0 235159.0 240229.0 272016.0 248788.0 274163.0 245469.0 250471.0 218744.0 236325.0 224774.0 False True 231805.58953712144 239672.76451012582 249651.89449212523 267084.699452439 258037.27136519674 234970.863086187 263439.16281598463 228907.6448042324 209707.58988742466 263625.886407472 0.8792975253531525 0.9091397198364535 0.9469930965210754 1.013120157098764 0.9788009625365952 0.8913042125271623 0.999291709952949 0.8683048843330297 0.7954741954410773 1.0 18.00813251533682 -10.455625478319016 9.592612920878274 0.9999999999898802 0.9250627684806888 0.12088496065293819 0.06335224460329292 0.0 0.0 0.06459383653030477 0.01566630663309527 3.50247078716813e-11 10.455625478319016 -0.0749372315091914 LIDLEDSADVGDQPGEVGY(ph)SGSPAEAPPSK ddPTM_PC-9_Lapatinib_30min_R1 1 LIDLEDSADVGDQPGEVGYSGSPAEAPPSK 30 0 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 LIDLEDSADVGDQPGEVGY(0.39)S(0.343)GS(0.265)PAEAPPS(0.001)K 86.869 1.7398e-08 3019100.0 32032.0 39617.0 42969.0 35244.0 43603.0 39006.0 34813.0 35745.0 40399.0 34110.0 True False 31575.21780605061 39525.26927056124 39436.25468513663 37835.96133053744 41038.35726679629 37337.80430742706 36615.44679868277 37405.84319353808 35848.83919967029 40005.86805128195 0.7892646590139122 0.987986792834875 0.9857617546152191 0.9457602890165264 1.0258084442559985 0.9333081901776309 0.9152519013397453 0.9350089128322125 0.8960895225099746 1.0 15.28792400923876 -4.754880408425661 24.996428808149567 0.9567445937401214 0.7892643767135853 0.6314402345874232 0.03873237022579429 153.05365851950765 583238.336119571 0.010025039035051884 0.0935317075373978 1.7584077596475418e-05 4.754880408425661 -0.16748021702653615 LIDLEDSADVGDQPGEVGYS(ph)GSPAEAPPSK ddPTM_PC-9_AZD4547_30min_R2 1 LIDLEDSADVGDQPGEVGYSGSPAEAPPSK 30 0 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 LIDLEDSADVGDQPGEVGY(0.307)S(0.346)GS(0.346)PAEAPPS(0.001)K 63.095 0.00022729 3097400.0 17886.0 13354.0 16074.0 17079.0 17948.0 15813.0 15423.0 19236.0 14084.0 18339.0 True False 23573.375948088677 17670.419348296968 15860.848257434973 13141.700417919628 15456.230005031113 14824.210610233871 16795.617121690037 16263.51819930557 14828.451486944143 17696.95719195716 1.3320581438035124 0.9985004290075215 0.8962471957972157 0.7425966099919263 0.8733834770225695 0.8376700270807638 0.9490680764783247 0.9190008216043459 0.8379096658313281 1.0 14.111213704747767 -4.74459686902464 2.1716049307363243 0.8748964508568864 1.482059671270238 0.8073320670982411 0.0661985330346644 0.3070044682399004 1.537485158554956 0.017782775232970043 0.3798411340204437 1.8005414803627378e-05 4.74459686902464 0.6071632204133517 LIDLEDSADVGDQPGEVGYSGS(ph)PAEAPPSK ddPTM_PC-9_AZD4547_30min_R2 1 LIDLEDSADVGDQPGEVGYSGSPAEAPPSK 30 0 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 LIDLEDS(0.001)ADVGDQPGEVGY(0.296)S(0.322)GS(0.38)PAEAPPS(0.001)K 43.622 0.018893 2538400.0 7742.0 6669.7 9381.1 12827.0 11551.0 12308.0 8865.9 9786.8 9375.0 12048.0 True False 10203.794956396207 8825.550091907764 9256.700484498146 9869.933325174488 9947.34303477348 11538.378814314712 9654.947924475893 8274.474938290907 9870.543360558171 11626.203187125793 0.8776549654400775 0.7591085369710968 0.7961929045544721 0.8489386574719338 0.8555968680977991 0.9924459970811165 0.8304472035347913 0.7117091285187237 0.848991128203252 1.0 13.505092406933693 -5.876014403101375 4.440919351918392 0.8617849386467868 0.8060081763281421 0.0925094319983858 0.08206271105152627 0.6110170748630583 20.79896920694687 0.02456460080607821 0.03767662111143798 1.3304102950317953e-06 5.876014403101375 -0.0557767623186447 LIDLES(ph)PTPESQK ddPTM_PC-9_AZD4547_30min_R2 4 LIDLESPTPESQK 13 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 LIDLES(0.896)PT(0.104)PES(0.001)QK;LIDLES(0.966)PT(0.034)PESQK;LIDLES(0.924)PT(0.076)PESQK;LIDLES(0.874)PT(0.038)PES(0.088)QK 237.07 5.230999999999999e-26 137814500.0 140108.0 141167.0 185737.0 243807.0 212815.0 190978.0 174604.0 197083.0 169355.0 183439.0 True False 184659.42957256007 186796.4720788554 183274.00602160007 187601.0629306009 183269.31070429535 179036.11546962938 190143.41774723213 166628.35086679884 178306.75955491504 177016.8564444859 1.0431742675899962 1.0552468043484688 1.0353477612403341 1.059792082509579 1.0353212365499795 1.011407156729036 1.0741543012705281 0.9413134670542238 1.007286894233339 1.0 17.433527222038613 -7.756385163378728 24.999971943321004 0.9807251346742802 1.0438633023498467 0.6111851492366087 0.022650715013419927 74.66989179227072 369349.9905815572 0.010380237892340619 0.005754359770361441 1.752325724836133e-08 7.756385163378728 0.06313816767556646 LIDLES(ph)PTPESQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LIDLESPTPESQK 13 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 LIDLES(0.717)PT(0.282)PESQK;LIDLES(0.619)PT(0.381)PESQK;LIDLES(0.983)PT(0.017)PESQK 198.48 6.8071e-07 90676000.0 112377.0 137231.0 134595.0 139088.0 166437.0 137702.0 163641.0 148906.0 142308.0 125033.0 True False 131400.2065530773 150854.3867519167 137804.25525438008 131295.35028937997 133824.86462800158 130480.66470948327 148139.7398217567 144997.3752789488 144388.98527971402 147700.4931393166 0.8896395926663274 1.0213533045527834 0.9329979360623935 0.888929667726548 0.9060556385669817 0.8834138731440054 1.0029739012585814 0.9816986537897466 0.9775795747920826 1.0 17.172315117387576 -7.276100023711528 24.99591743493501 0.9890379242630484 0.9234775712821892 0.4490217339194663 0.03796975864519535 899.0605292229443 1532862.581493569 0.016883594297369395 0.011441632674109047 5.2954146950486116e-08 7.276100023711528 -0.06556035298085916 LIDLES(ph)PTPESQK ddPTM_PC-9_Lapatinib_30min_R1 5 LIDLESPTPESQK 13 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 LIDLES(0.821)PT(0.178)PESQK;LIDLES(0.747)PT(0.253)PESQK;LIDLES(0.618)PT(0.378)PES(0.004)QK;LIDLES(0.895)PT(0.105)PESQK;LIDLES(0.998)PT(0.002)PESQK 180.3 9.8568e-05 168250600.0 196566.0 176946.0 184020.0 174117.0 211868.0 209844.0 185030.0 188338.0 207752.0 175822.0 True False 193762.93279421047 176536.2924085299 168890.5859377418 186922.14501728513 199406.34078851467 200869.46129025595 194609.94804125684 197088.87104167265 184352.78203445385 206212.59843191155 0.9396270366972181 0.8560887828917962 0.8190119673677797 0.9064535651006994 0.9669939775981039 0.9740891818332824 0.9437345221442145 0.9557557226880519 0.8939937881405655 1.0 17.653772950401873 -6.037457110972563 5.032243396402568 0.9530490542426023 0.8686590393866627 0.5056921380164454 0.03759510865039624 0.16042983832594476 10.12886661168573 0.011156994937799643 0.015159689211802519 9.173665260305532e-07 6.037457110972563 -0.08439001485593967 LIDLESPT(ph)PESQK ddPTM_PC-9_AZD4547_30min_R2 1 LIDLESPTPESQK 13 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 LIDLES(0.215)PT(0.776)PES(0.01)QK 102.33 0.0043446000000000005 98096000.0 24579.0 21952.0 30640.0 36374.0 34921.0 24762.0 29626.0 31330.0 25374.0 27538.0 True False 32394.610725040326 29047.554705243005 30233.693580179635 27988.536272697947 30072.821930337155 23213.628225549306 32262.65660683323 26488.6683917781 26715.217837952314 26573.903001914845 1.219038495124561 1.0930857504503542 1.1377212289064604 1.0532339291929065 1.1316674832511502 0.8735498215627788 1.214072942334006 0.996792544545278 1.0053178050671474 1.0 14.6977225165979 -1.5228787452805024 0.33465987433648087 1.0190099775680677 2.93230853884506 0.3007763539239726 0.0857451336387969 77.5701910155293 1.1021537868926188 0.07361323702476262 92.23520998888692 0.029999999999988616 1.5228787452805024 1.9132985612769924 LIDLESPT(ph)PESQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LIDLESPTPESQK 13 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 LIDLES(0.377)PT(0.623)PESQK;LIDLES(0.14)PT(0.852)PES(0.008)QK;LIDLES(0.47)PT(0.528)PES(0.001)QK 201.3 6.251e-07 87622100.0 291836.0 295084.0 304892.0 345545.0 411638.0 395773.0 372557.0 359239.0 361127.0 307288.0 True False 341238.07077626244 324377.9893777835 312161.78158934874 326185.23392200464 330980.4888681078 375017.96716145205 337265.7038808986 349809.35689518275 366407.7991898366 362996.88190953125 0.9400578566438162 0.8936109524451159 0.859957198384828 0.8985896303189153 0.9117998125135333 1.0331162217942047 0.929114603152306 0.9636704179248702 1.0093965470512098 1.0 18.4695976301703 -6.6133234980222095 7.2512349972280274 0.9809608531526791 0.8962677508227235 0.6464165827884978 0.03184436029730947 0.15186612044688427 10.399204501455944 0.010633874702221912 0.010624958585532945 2.43599561378496e-07 6.6133234980222095 -0.08469310232995564 LIDLESPT(ph)PESQK ddPTM_PC-9_Lapatinib_30min_R1 2 LIDLESPTPESQK 13 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 LIDLES(0.066)PT(0.912)PES(0.022)QK;LIDLES(0.137)PT(0.489)PES(0.374)QK 124.48 0.00037445 24700200.0 53090.0 41450.0 48805.0 38492.0 53559.0 49122.0 47943.0 47339.0 54119.0 42880.0 True False 52332.926864486384 41354.02507168042 44792.441292748095 41322.83008554784 50408.764921045404 47021.16656897483 50425.25395309935 49538.542759516 48023.54832166528 50291.75086599153 1.040586695896387 0.8222824689852862 0.8906518568443359 0.8216621886093711 1.0023267047386293 0.9349677782002148 1.0026545722670017 0.9850232275968568 0.9548991135669515 1.0 15.618034160083129 -6.279392476960259 24.991525743996867 0.9781129912681547 0.8884631352293592 0.3288607178478704 0.06008693638905373 908.1090276872886 1264126.0186001363 0.017915603759260285 0.020358660436564084 5.255421132193551e-07 6.279392476960259 -0.0896498560387955 LIDLESPTPES(ph)QK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LIDLESPTPESQK 13 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 LIDLES(0.102)PT(0.367)PES(0.531)QK;LIDLES(0.045)PT(0.377)PES(0.578)QK 132.51 5.5256e-05 7245700.0 47397.0 46078.0 47074.0 48314.0 55110.0 48071.0 58977.0 49008.0 48668.0 48076.0 True False 55420.37596657871 50652.3193211068 48196.422689139166 45607.123216101376 44311.59111044515 45550.072135840936 53390.27160349625 47721.591928268215 49379.67742918975 56791.798230593406 0.975851754888157 0.8918949725001082 0.8486511114412298 0.8030582696276218 0.7802463118094183 0.802053704143909 0.9401053191996873 0.8402902076546834 0.8694860696027268 1.0 15.793394972898536 -8.584761396805474 16.438330084052307 1.0000000010672523 0.8569449940693838 0.3345184572308797 0.05866996632200987 564.7625656720938 150023.77411961916 0.060583914318808336 0.015642691250002352 2.6015884941373308e-09 8.584761396805474 -0.14305500699786844 LIDLHSPS(ph)EIVK ddPTM_PC-9_AZD4547_30min_R2 1 LIDLHSPSEIVK 12 0 P60866;P60866-2;G3XAN0 P60866 RPS20 40S ribosomal protein S20 1 LIDLHS(0.394)PS(0.606)EIVK 58.07899999999999 0.039533 2383100.0 24589.0 31987.0 36366.0 51203.0 41121.0 43916.0 26522.0 39283.0 30269.0 34751.0 True False 32407.79051702742 42326.172210122444 35883.763078877695 39398.93942846411 35412.05895012727 41169.92557762796 28882.406620077993 33212.71498353719 31868.957544611752 33534.37806738119 0.9664049964460322 1.262172571832874 1.0700590005508928 1.1748820672713582 1.0559927152659048 1.227693130163456 0.8612775391881157 0.9904079603564533 0.9503369193422021 1.0 15.033353225454068 -7.263461256033663 24.999995332212023 0.9497062686098848 1.1288508999274718 0.4907778179153436 0.08764869746856828 146.7440650479961 1814432.3091516925 0.032604412548080344 0.023222169966536345 5.451785295936207e-08 7.263461256033663 0.17914463131758696 LIDLHSPS(ph)EIVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LIDLHSPSEIVK 12 0 P60866;P60866-2;G3XAN0 P60866 RPS20 40S ribosomal protein S20 1 LIDLHS(0.011)PS(0.989)EIVK 63.29 0.027281 1674600.0 13901.0 16668.0 16627.0 20680.0 20518.0 15656.0 22544.0 16040.0 17879.0 14261.0 True False 16254.16474273501 18322.688885025556 17023.45073824865 19521.36664546461 16497.645189695402 14834.971799187157 20408.469115574182 15618.96699578482 18140.446551255103 16846.406409986124 0.964844629006454 1.087631892470808 1.0105093231134197 1.1587852133196097 0.9792975895390968 0.8806015620276951 1.2114434745843812 0.927139391967078 1.0768140165787468 1.0 14.040153255383084 LIDLHSPS(ph)EIVK ddPTM_PC-9_Lapatinib_30min_R1 1 LIDLHSPSEIVK 12 0 P60866;P60866-2;G3XAN0 P60866 RPS20 40S ribosomal protein S20 1 LIDLHS(0.11)PS(0.89)EIVK 67.385 0.020975999999999998 814040.0 12188.0 10207.0 12378.0 10687.0 11011.0 10649.0 11519.0 13823.0 11033.0 11258.0 True False 12014.196884994535 10183.366318616212 11360.328620461749 11472.9576307869 10363.354628458917 10193.567094031454 12115.397457100129 14465.267043342474 9790.347357359395 13203.930299657939 0.9098955093170837 0.7712375094012744 0.8603747795272783 0.8689047405138239 0.7848689286649286 0.7720100653890553 0.9175599372418674 1.0955273706433615 0.7414722082873327 1.0 13.68867980760581 -7.446572446277603 6.740418249471655 0.9518251343601227 0.8275307316014596 0.26025104399341836 0.09214776957589915 0.311295279412759 23.11443771123412 0.037061707157444494 0.02468913169762876 3.5762473888777234e-08 7.446572446277603 -0.1242944027586631 LIDLHSPSEIVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LIDLHSPSEIVK 12 0 P60866;P60866-2;G3XAN0 P60866 RPS20 40S ribosomal protein S20 0 142.19 6.7735e-05 9451600.0 50590.0 52344.0 65654.0 64829.0 66254.0 66877.0 66398.0 58036.0 57264.0 47177.0 False True 59153.88780195411 57540.366390555435 67219.44035418163 61196.84130845382 53272.00430831857 63369.85238977009 60108.30076010887 56512.61649422491 58101.37766715545 55729.81664707346 1.0614405602043275 1.0324879903149127 1.2061665442014606 1.0980987376291225 0.9558977135288321 1.1370906312338969 1.078566275226842 1.0140463381049463 1.0425546173083728 1.0 15.766161786459223 -8.043967002688927 0.7615964530490212 1.0005043535911853 1.0859446023078763 0.15784820231794905 0.06267667767468629 1.229952746130577 1.4574900810353475 0.0615663156004828 0.025962516002070134 9.037181348193902e-09 8.043967002688927 0.08544024871669098 LIDLHSPSEIVK ddPTM_PC-9_Lapatinib_30min_R1 2 LIDLHSPSEIVK 12 0 P60866;P60866-2;G3XAN0 P60866 RPS20 40S ribosomal protein S20 0 ; 155.47 5.563e-05 37403000.0 385320.0 360670.0 366840.0 358320.0 407080.0 394040.0 394210.0 332620.0 355970.0 355630.0 False True 379825.2661409661 359834.89077449805 336679.83124334965 384672.04812048026 383136.35475007293 377187.827752104 414620.2649156561 348074.73948900925 315876.91006972035 417100.17165281065 0.9106332050544641 0.8627061680377837 0.807191782993554 0.9222533920237195 0.9185715585583388 0.9043099317304305 0.9940544096941327 0.8345111393978103 0.7573166628486853 1.0 18.670034380388735 -4.390486367654729 14.086201912817868 0.886969298093206 2.644815248319903 0.00716733831225147 0.0730084545192985 434430.0120686723 354449.1635061513 0.018403974800670363 24248351.961361617 4.069243068141904e-05 4.390486367654729 1.7578459502266968 LIDVNHYAK ddPTM_PC-9_Lapatinib_30min_R1 1 LIDVNHYAK 9 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 85.53299999999999 0.010375 2952100.0 51336.0 61286.0 60355.0 53714.0 56361.0 52027.0 50342.0 49336.0 55137.0 47073.0 False True 50603.939226130606 61144.096032400616 55392.844877037416 57664.30674465122 53045.95678998936 49801.926490860555 52948.46243470223 51628.330669922914 48926.89044165004 55209.50532917018 0.9165801961894015 1.1074921912059748 1.003320796786244 1.044463383630138 0.9608120281773708 0.902053481441854 0.9590461301729267 0.9351348171316591 0.8862041083313114 1.0 15.752629054355262 -6.423151099922073 4.506754435306721 0.9335267221705282 1.0228201066889522 0.34626314511808176 0.05261632021894556 0.22918626949128562 7.770845553124849 0.01579269563781666 0.01781307748558361 3.7744084869675086e-07 6.423151099922073 0.08929338451842395 LIEDKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LIEDKPR 7 1 Q13247-3;Q13247;A0A590UJK4;A0A590UK01;A0A590UJP7;A0A590UK80 Q13247-3 SRSF6 Serine/arginine-rich splicing factor 6 0 ; 94.262 0.017505 5195800.0 49103.0 53496.0 66065.0 68364.0 75238.0 69225.0 64781.0 64788.0 60707.0 47673.0 False True 57415.16807154284 58806.72933725271 67640.24015290765 64533.78671907844 60495.65400050217 65594.71913635219 58644.47470617514 63087.383648560295 61594.725028639434 56315.73752073965 1.0195226165758426 1.044232605771978 1.201089484586746 1.145928111042003 1.0742228844685406 1.1647671152703154 1.041351446113582 1.120244294506963 1.093739116991155 1.0 15.781250521578496 -8.578472464888332 17.48117070482291 0.9999999988813435 1.1037390966226392 0.22915258146983186 0.05536308813228197 1002.0266326063668 315084.4277567403 0.05468506037288216 0.01411962187700486 2.6395356687365545e-09 8.578472464888332 0.10373909774129575 LIEDKPR ddPTM_PC-9_Lapatinib_30min_R1 1 LIEDKPR 7 1 Q13247-3;Q13247;A0A590UJK4;A0A590UK01;A0A590UJP7;A0A590UK80 Q13247-3 SRSF6 Serine/arginine-rich splicing factor 6 0 78.616 0.036387 2049600.0 22537.0 20352.0 21045.0 16458.0 20289.0 21627.0 17850.0 17622.0 25661.0 19761.0 False True 22215.618247220365 20304.876194423145 19314.761336049258 17668.376222278563 19095.640909708745 20702.063624999362 18774.185659279217 18440.78245227382 22770.787957690503 23176.662520122638 0.9585339661365019 0.876091463850495 0.8333711257727308 0.7623347928951537 0.8239167694282715 0.8932288506606696 0.8100469876963059 0.7956616892644921 0.9824877908076824 1.0 14.500385210245291 -8.277043133399133 21.527904597425437 0.9912443457612538 0.8419515813927443 0.557585471310254 0.05238134366727607 114.09794209050412 157407.08842915524 0.05207431116806159 0.013754406232778585 5.2839277008582285e-09 8.277043133399133 -0.14929276436850947 LIEDTEDWRPR ddPTM_PC-9_AZD4547_30min_R2 2 LIEDTEDWRPR 11 1 Q96HC4;Q96HC4-7;Q96HC4-4;H0Y8Y3;Q96HC4-6;H0YBI4;Q96HC4-2;Q96HC4-3 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 0 ; 136.52 0.00010659999999999999 5451500.0 23534.1 20321.6 30271.4 44259.0 38201.7 32903.9 25126.8 32072.0 25245.7 31420.8 False True 31017.454260310493 26890.159789452722 29869.981457018617 34055.771344733555 32898.05336434126 30846.41393145351 27363.036522938528 27116.00934124187 26580.136161881946 30320.767355747186 1.0229772187619537 0.8868561759653419 0.9851327674712321 1.1231830298080636 1.0850006854495242 1.0173361897322393 0.9024519795918677 0.8943048512953328 0.8766313810604724 1.0 14.888018645140322 -7.257953905809473 22.20503170439797 0.909539107781664 1.0200741508462934 0.3612103110134506 0.06586285108468015 74.27286684407865 473179.70180331636 0.028572820330835032 0.02117458074092256 5.521360375688512e-08 7.257953905809473 0.11053504306462936 LIEDTEDWRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LIEDTEDWRPR 11 1 Q96HC4;Q96HC4-7;Q96HC4-4;H0Y8Y3;Q96HC4-6;H0YBI4;Q96HC4-2;Q96HC4-3 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 0 ; 112.3 0.0022105999999999996 2701300.0 19102.2 20348.4 21627.3 22541.0 26945.0 23051.5 20332.5 17897.9 19674.3 14081.900000000001 False True 22335.82517435239 22368.45467410934 22142.976853991986 21278.100848908016 21665.32067630093 21842.638760153484 18406.45840544766 17428.099089392577 19961.999417381194 16634.836997740946 1.3427137986014324 1.3446753146512367 1.3311207592234935 1.2791289059097866 1.3024065507370548 1.3130659929592199 1.1065006773404096 1.0476867967963472 1.2000117235950125 1.0 14.021920109088356 -7.271000711912384 4.992874614157716 1.0902916944754142 1.3189263172452788 0.8345995607026495 0.05027559930505452 0.07161735349749306 5.514739231072311 0.02014212429856654 0.014158639018017656 5.357957792153685e-08 7.271000711912384 0.22863462276986457 LIEDTEDWRPR ddPTM_PC-9_Lapatinib_30min_R1 2 LIEDTEDWRPR 11 1 Q96HC4;Q96HC4-7;Q96HC4-4;H0Y8Y3;Q96HC4-6;H0YBI4;Q96HC4-2;Q96HC4-3 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 0 ; 172.56 0.00078739 7194600.0 33826.0 28886.0 37178.0 30987.0 36046.0 37423.0 30114.0 31185.0 34147.0 29826.0 False True 33343.6350370713 28819.11624175056 34121.36835123015 33265.887349601755 33925.84514916268 35822.50552727384 31673.155571066363 32633.96894643962 30301.005276148953 34981.38435935314 0.9531822610146659 0.8238415022601886 0.9754150379159295 0.9509597163986249 0.9698256878759505 1.0240448222197303 0.9054288774194198 0.932895296858488 0.8662037203809868 1.0 15.094299763401757 -5.288407158886078 24.97613733764443 0.9520526395007913 0.8885118362019572 0.20024450433084007 0.05159460980467819 1018.6694539009161 943436.2063387844 0.013429456362141465 0.027967665629708684 5.1474583481962494e-06 5.288407158886078 -0.06354080329883416 LIEEVMIGEDK ddPTM_PC-9_Lapatinib_30min_R1 1 LIEEVMIGEDK 11 0 P78371;P78371-2;F5GWF6;F8VQ14 P78371 CCT2 T-complex protein 1 subunit beta 0 145.99 0.0029116 2840100.0 18941.0 17081.0 19368.0 17602.0 16372.0 15898.0 17190.0 15952.0 17596.0 17923.0 False True 18670.897866646013 17041.449993953513 17775.637802642053 18896.509798550684 15409.031148590453 15218.07960004807 18080.014088684024 16693.188155639087 15614.153185905549 21020.96666910368 0.8882035807653049 0.8106882172550511 0.8456146704598716 0.8989362904192464 0.7330315199651798 0.723947658525875 0.8600943226487188 0.7941208612529936 0.7427894935419411 1.0 14.359541394075771 -4.759252090550461 24.0006087912536 0.8151066968609599 0.8882037202662025 0.04700179382624825 0.08056275156200492 105.27577463217644 1154691.8883150534 0.01935860011488762 0.12371136849871092 1.7407961176521527e-05 4.759252090550461 0.0730970234052426 LIEILSEK ddPTM_PC-9_Lapatinib_30min_R1 1 LIEILSEK 8 0 Q9P2E9;A0A087WVV2;Q9P2E9-3;F8W7S5 Q9P2E9 RRBP1 Ribosome-binding protein 1 0 111.95 0.007882 0.0 10801.0 9322.5 10301.0 8065.7 8468.7 9143.9 9341.8 8532.9 8000.1 8102.0 False True 10646.975759339191 9300.914324022695 9454.091543009901 8658.878484386447 7970.587716104804 8752.83671247198 9825.472694221546 8929.369684882946 7099.044493212262 9502.419904763596 1.1204488820791665 0.9787942879013497 0.9949140995411635 0.9112287786867556 0.83879556954846 0.9211165997920333 1.0339968968637139 0.9396942857057519 0.7470775407066033 1.0 13.214079244424429 -3.9885335194587777 0.8862323067723282 0.9148221640894368 1.7167840648188668 0.38669478431735305 0.07729810268182026 8.506390486235087 1.8799182971726267 0.02702328673943599 9.24943052823845 0.00010267541822783221 3.9885335194587777 0.80196190072943 LIESDLNSK ddPTM_PC-9_Lapatinib_30min_R1 1 LIESDLNSK 9 0 O60237;O60237-6;H7C4R6;O60237-2;O60237-5 O60237 PPP1R12B Protein phosphatase 1 regulatory subunit 12B 0 95.531 0.024863 6135600.0 28083.0 31474.0 35580.0 33539.0 33533.0 28917.0 28962.0 29774.0 28334.0 24350.0 False True 27682.531270208525 31401.123886756788 32654.749742771768 36005.56994282419 31560.654868414556 27680.287318819377 30461.510647845636 31157.408735330875 25142.72654975266 28558.865055664486 0.9693148245300405 1.099522821567048 1.1434190287017336 1.2607493285410758 1.10510886223592 0.9692362516811274 1.066621890907523 1.090989038766125 0.880382553744577 1.0 14.80165102659506 -6.654700126030422 6.307673999648342 1.0116344697985353 1.126156648930588 0.30580181175859267 0.08503509526983752 0.29183500171713683 15.311435398510758 0.029421439130923873 0.029328598846341154 2.214623346731253e-07 6.654700126030422 0.11452217913205276 LIESLS(ph)PDFCHQNK ddPTM_PC-9_AZD4547_30min_R2 2 LIESLSPDFCHQNK 14 0 Q9H6R7;Q9H6R7-2 Q9H6R7 C2orf44 WD repeat and coiled-coil-containing protein C2orf44 1 LIES(0.269)LS(0.731)PDFCHQNK;LIES(0.017)LS(0.983)PDFCHQNK 132.25 7.8354e-06 31414000.0 82892.0 72873.0 107839.0 139683.0 127495.0 118539.0 100738.0 114422.0 90050.0 109615.0 True False 109249.93173929158 96427.77214081504 106408.98439924912 107481.2424308372 109794.5199738938 111126.73759100183 109703.48684463518 96740.70905598567 94809.85915928138 105777.41221420918 1.0328285543424927 0.9116102400533278 1.0059707660815236 1.0161076942700924 1.0379769903195362 1.050571528125114 1.0371163800308834 0.9145686875008501 0.8963147913590712 1.0 16.69067206062548 -7.7661530855408145 24.998703870212392 0.9290812856658722 1.0114916817857431 0.37856326222110004 0.04436486598842474 124.14430512231361 658370.5162732112 0.02438030955343257 0.01230955438701001 1.7133532569071363e-08 7.7661530855408145 0.08241039611987089 LIESLS(ph)PDFCHQNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LIESLSPDFCHQNK 14 0 Q9H6R7;Q9H6R7-2 Q9H6R7 C2orf44 WD repeat and coiled-coil-containing protein C2orf44 1 LIES(0.284)LS(0.716)PDFCHQNK;LIES(0.212)LS(0.788)PDFCHQNK;LIES(0.26)LS(0.74)PDFCHQNK;LIES(0.257)LS(0.743)PDFCHQNK;LIES(0.001)LS(0.999)PDFCHQNK 125.28 0.00075549 23369800.0 183664.0 198789.5 201769.0 205112.0 219512.0 206869.0 232327.0 215240.0 222323.0 171975.0 True False 214754.68767064827 218524.00780596273 206579.93817319398 193620.23962207642 176500.1993800772 196020.42546793885 210319.30465817938 209590.1780656307 225574.05328120672 203152.70614664932 1.0571096577745012 1.075663779975529 1.0168702258096953 0.9530773342606044 0.8688055538510397 0.9648920222920294 1.0352769039973149 1.0316878472410522 1.110366962664884 1.0 17.632205056915474 -9.91132875222799 10.760706262652032 1.0000029152797592 1.0084560879308822 0.0 0.06562518152298541 0.0 0.0 0.07117195405880627 0.01726173436270976 1.2265104358185104e-10 9.91132875222799 0.008453172651122998 LIESLS(ph)PDFCHQNK ddPTM_PC-9_Lapatinib_30min_R1 1 LIESLSPDFCHQNK 14 0 Q9H6R7;Q9H6R7-2 Q9H6R7 C2orf44 WD repeat and coiled-coil-containing protein C2orf44 1 LIES(0.083)LS(0.917)PDFCHQNK 102.36 0.00083908 14647000.0 62385.0 60219.0 61350.0 53174.0 62867.0 66158.0 51542.0 51656.0 63245.0 51398.0 True False 61495.37845999216 60079.56660534433 56306.03981784851 57084.59334326406 59169.28666127752 63328.576561830516 54210.59256305712 54056.12633949933 56121.68210062495 60282.07581646994 1.0201270879791224 0.9966406397194723 0.9340428154676267 0.9469579899182523 0.9815402980053254 1.050537422676613 0.8992821137762811 0.8967197231905941 0.9309845644912529 1.0 15.879441476620618 -7.2915977091183235 24.99879215954944 0.9231399083288285 0.9840327687932817 0.29959764681086853 0.04123179893208653 862.9683106337559 715327.0061004546 0.017715300306432334 0.01194530328100919 5.1097810443151774e-08 7.2915977091183235 0.06089286046445319 LIEVDDER ddPTM_PC-9_AZD4547_30min_R2 4 LIEVDDER 8 0 P62753;A2A3R7 P62753 RPS6 40S ribosomal protein S6 0 ;;; 153.04 0.00051874 50446600.0 115036.0 111256.0 163670.0 200455.0 160565.0 134932.0 134639.0 158956.0 134624.0 148016.0 False True 151615.05510255686 147217.3262703404 161499.62885992177 154243.19674887732 138273.32130364503 126494.68070954763 146621.61016969586 134393.00264549872 141739.94979965687 142834.0048925639 1.0614773086884866 1.0306882200850807 1.1306805335423988 1.0798772803779821 0.9680700433181209 0.885606202841499 1.026517531871916 0.9409034126473294 0.992340373752525 1.0 17.123979961154205 -6.266605926654143 10.517203526724593 0.9646421499704615 1.0764171741848991 0.6030381445630297 0.04235382463379041 0.1333012499029348 243.77310631679816 0.01285403840346824 0.015300632104840518 5.412452192939549e-07 6.266605926654143 0.11177502421443763 LIEVDDER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LIEVDDER 8 0 P62753;A2A3R7 P62753 RPS6 40S ribosomal protein S6 0 ;;; 130.22 0.015388999999999998 36024300.0 141780.0 136696.0 174018.0 161631.0 191341.0 152018.0 165706.0 161324.0 152919.0 122432.0 False True 165780.55371735583 150266.27548760799 178167.24908694017 152575.33908477222 153849.10460286113 144045.90846760545 150009.12807245125 157089.41593690708 155155.15108067455 144627.95242882156 1.146255277305018 1.0389850161334568 1.2319005150448004 1.054950557775904 1.0637577454370568 0.9959755776705573 1.0372070236303597 1.0861622065362393 1.0727881331033429 1.0 17.141986885184913 -5.963277130856354 24.999528656722582 1.0457146979317935 1.1314382996549401 0.41668828813646475 0.051176681021771926 177.476479705302 120818.1614432938 0.01408171588424461 0.020886481643550406 1.0882354497723786e-06 5.963277130856354 0.08572360172314664 LIEVDDER ddPTM_PC-9_Lapatinib_30min_R1 3 LIEVDDER 8 0 P62753;A2A3R7 P62753 RPS6 40S ribosomal protein S6 0 ;; 139.97 0.011986 61894400.0 171338.0 158336.0 181899.0 165338.0 172514.0 172464.0 154894.0 146370.0 169443.0 141073.0 False True 168894.68870045897 157969.3827201351 166943.96637044527 177497.50807139973 162367.06569557358 165088.11675321986 162913.6534178371 153170.88454995558 150358.54502610784 165457.2800820436 1.0207752032229158 0.9547442254689816 1.0089853180691988 1.0727694059964352 0.9813231887715202 0.997768829944257 0.9846266863389437 0.925742792786176 0.9087454172554456 1.0 17.336099245731837 -7.5973573570663 3.5958454166965756 0.9381859649953913 1.0051460399757748 0.36120995413218426 0.03592056043478156 0.24266399747484474 6.255723212972675 0.01873539336448779 0.010236757484795793 2.5272176321264648e-08 7.5973573570663 0.06696007498038348 LIFPITSQNPNELS(ph)DFTLRVQVK ddPTM_PC-9_Lapatinib_30min_R1 1 LIFPITSQNPNELSDFTLRVQVK 23 1 Q9P0V3 Q9P0V3 SH3BP4 SH3 domain-binding protein 4 1 LIFPIT(0.008)S(0.008)QNPNELS(0.922)DFT(0.062)LRVQVK 41.961999999999996 0.042522000000000004 11190000.0 24191.0 17386.0 18132.0 16910.0 21235.0 20770.0 21087.0 21974.0 22421.0 18068.0 True False 23846.031903913914 17345.743785192662 16641.256951544077 18153.61781010635 19985.999049616297 19881.715517234792 22178.781680516575 22994.992260030915 19895.710876403053 21191.02972590332 1.1252889648286035 0.8185418079985849 0.7852972303277113 0.8566652043301074 0.9431348692407322 0.9382137524412955 1.046611795999977 1.0851285924969696 0.9388741903411656 1.0 14.371166073175509 -6.913118107712065 1.9985309131099571 1.02324227282378 0.8872562607852068 0.23138519163787585 0.0936504726127882 0.43888625714794205 3.5718038142600332 0.04078307796774504 0.03367225222520776 1.2214674331891612e-07 6.913118107712065 -0.1359860120385732 LIGEYGLR ddPTM_PC-9_Lapatinib_30min_R1 1 LIGEYGLR 8 0 P46781;B5MCT8;C9JM19;F2Z3C0;A8MXK4 P46781 RPS9 40S ribosomal protein S9 0 104.21 0.017793 8313400.0 30116.0 31298.0 36560.0 27090.0 32424.0 31312.0 36221.0 29811.0 31681.0 32010.0 False True 29686.54031740199 31225.531403943398 33554.17792568118 29082.288969590845 30516.884068036696 29972.858751837048 38096.34614928588 31196.127890406027 28112.752164280144 37542.885849356055 0.790736770650016 0.8317296525695557 0.8937559584609479 0.7746418079389513 0.8128539769288974 0.7983632071361171 1.0147420819526403 0.8309464545582106 0.7488170269351401 1.0 15.196251931170936 LIGTAVPQRTS(ph)PTGPK ddPTM_PC-9_AZD4547_30min_R2 1 LIGTAVPQRTSPTGPK 16 1 C9JB30;Q9UPY8 C9JB30 MAPRE3 Microtubule-associated protein RP/EB family member 3 1 LIGTAVPQRT(0.03)S(0.915)PT(0.055)GPK 165.9 0.00025166 7136600.0 23827.0 15962.0 26957.0 45724.0 40429.0 24671.0 20824.0 24742.0 20149.0 27654.0 True False 31403.49036761203 21121.4043460773 26599.53256660911 35183.03822875794 34816.13120533779 23128.318469934857 22677.29565856664 20918.6924145986 21214.035005001242 26685.84187722249 1.1767846977470198 0.7914835306022451 0.996765726522308 1.3184158997355138 1.3046667729473003 0.8666887324126682 0.8497875301405681 0.783887295399648 0.7949546843080236 1.0 14.70378690531957 -6.892143903575431 9.242154686653839 0.8419503089760727 1.1036712789411247 0.4166245302621072 0.15212241952193906 0.3126362518692864 24.707138530621428 0.05892314142481719 0.05197627239313445 1.281905752513248e-07 6.892143903575431 0.261720969965052 LIGTAVPQRTS(ph)PTGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LIGTAVPQRTSPTGPK 16 1 C9JB30;Q9UPY8 C9JB30 MAPRE3 Microtubule-associated protein RP/EB family member 3 1 LIGTAVPQRT(0.155)S(0.69)PT(0.155)GPK 120.77 0.00041703 5822900.0 15512.0 10449.0 16313.0 21647.0 24548.0 25681.0 22036.0 24912.0 22939.0 19888.0 True False 18137.875224034633 11486.307664964726 16701.963787397002 20434.18877052091 19737.99561929245 24334.24315118327 19948.590553175698 24258.08639644585 23274.439478675602 23493.536966678614 0.772036805260952 0.48891351188439625 0.7109173817073927 0.8697791566890569 0.8401457663563929 1.0357845728251582 0.8491097181948044 1.0325429683428091 0.9906741378144226 1.0 14.519976307891282 -5.920583311215905 1.3584183573249462 0.9699272209590601 0.6185186387973075 0.7001382982439825 0.08924535886129967 0.22728092758023874 0.8509890028864325 0.03030495954746317 0.06042747258014676 1.2006507286951385e-06 5.920583311215905 -0.35140858216175264 LIGTAVPQRTS(ph)PTGPK ddPTM_PC-9_Lapatinib_30min_R1 1 LIGTAVPQRTSPTGPK 16 1 C9JB30;Q9UPY8 C9JB30 MAPRE3 Microtubule-associated protein RP/EB family member 3 1 LIGTAVPQRT(0.224)S(0.776)PT(0.001)GPK 110.57 0.0026829999999999996 7612100.0 53355.0 23358.0 31219.0 24583.0 23144.0 25176.0 12866.0 10371.0 29163.0 18005.0 True False 52594.14791589134 23303.91598611123 28652.294328824984 26390.915826484008 21782.715422854715 24099.281168122438 13532.138526178514 10852.874521196907 25878.355839995664 21117.140259845553 2.490590452529201 1.1035545390785633 1.356826444123573 1.249739098274902 1.0315182432289263 1.1412189752770385 0.6408130248540332 0.5139367541084032 1.2254668729555018 1.0 14.366126853815636 -2.0395758046335346 0.8615118588793992 0.9395975277680051 199.9999999998579 0.7368041192030305 0.25915636908422074 139.10499427521 1.005386107405645 0.09247836457445664 53467.29185620671 0.009129020774146571 2.0395758046335346 199.0604024720899 up LIGTAVPQRTSPT(ph)GPK ddPTM_PC-9_AZD4547_30min_R2 1 LIGTAVPQRTSPTGPK 16 1 C9JB30;Q9UPY8 C9JB30 MAPRE3 Microtubule-associated protein RP/EB family member 3 1 LIGTAVPQRT(0.225)S(0.044)PT(0.731)GPK 112.62 0.003358 10663000.0 58675.0 39692.0 74600.0 127430.0 116750.0 76186.0 57741.0 73660.0 56866.0 86471.0 True False 77332.42948418339 52521.66278063522 73610.75525722599 98052.98227387415 100541.27775169276 71422.07737629022 62879.83714086134 62277.53953840976 59871.8206657601 83443.67660972383 0.9267620103303515 0.6294265175572906 0.8821609766970407 1.1750798413698837 1.2048999017856856 0.8559315729859306 0.7535602420175941 0.7463422282995672 0.7175117767855298 1.0 16.348515105357265 -6.992985778587862 24.944182864441395 0.7862911645053232 0.9601243222566725 0.16945786901919813 0.1660549987226829 317.2997839067728 1128383.935847342 0.0653768427951243 0.05753030443649168 1.0162819715070398e-07 6.992985778587862 0.17383315775134933 LIGTAVPQRTSPT(ph)GPK ddPTM_PC-9_Lapatinib_30min_R1 1 LIGTAVPQRTSPTGPK 16 1 C9JB30;Q9UPY8 C9JB30 MAPRE3 Microtubule-associated protein RP/EB family member 3 1 LIGTAVPQRT(0.011)S(0.119)PT(0.869)GPK 149.31 0.0003151 5963400.0 60674.0 29221.0 39321.0 32435.0 32829.0 31759.0 26180.0 20864.0 39240.0 25455.0 True False 59808.777633751124 29153.34056983289 36088.1791634494 34820.37809998813 30898.062764297316 30400.741603844963 27535.472300276182 21833.417607776697 34820.37798448133 29854.86283334455 2.003317783357939 0.9765022446283647 1.2087873042626387 1.1663218248351037 1.034942378961046 1.0182844173007128 0.9223111308192692 0.7313186374244938 1.1663218209661597 1.0 14.865678319889176 -4.759766447024422 24.999327689300976 1.0236354165156865 2.003318998439834 0.8322315594172309 0.1317772717244895 17.690192477732502 264271.78084780445 0.035078291235494 0.2179093537559354 1.7387356269660273e-05 4.759766447024422 0.9796835819241476 LIHEQEQQSS(ph)S ddPTM_PC-9_AZD4547_30min_R2 2 LIHEQEQQSSS 11 0 Q96FQ6 Q96FQ6 S100A16 Protein S100-A16 1 LIHEQEQQSS(0.611)S(0.388);LIHEQEQQS(0.032)S(0.573)S(0.395) 105.52 0.002548 61537000.0 99641.0 100675.0 146814.0 188941.0 156471.0 135299.0 108589.0 149784.0 113887.0 131554.0 True False 131324.76533844945 133216.224943073 144867.15043343647 145383.57155935085 134747.70253606097 126838.73214153117 118253.21063523329 126638.32449390675 119906.83431508132 126948.33450192146 1.0344741099101362 1.0493735539402187 1.1411504609479046 1.1452184239341112 1.0614373403537756 0.9991366380597247 0.9315065936012216 0.9975579828657775 0.9445325516520773 1.0 16.953881942115572 -6.761671023548092 2.986741075781385 0.968213512826879 1.093614562078795 0.690397015082747 0.03811459769738578 0.15314427711892925 2.814818768797435 0.014970018811041349 0.013915824089789438 1.731127185072272e-07 6.761671023548092 0.12540104925191597 LIHEQEQQSS(ph)S ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LIHEQEQQSSS 11 0 Q96FQ6 Q96FQ6 S100A16 Protein S100-A16 1 LIHEQEQQS(0.137)S(0.522)S(0.341);LIHEQEQQS(0.005)S(0.574)S(0.421) 74.173 0.023132 42914000.0 32181.0 38233.0 40489.0 40573.0 60560.0 61139.0 40445.0 37618.0 40442.0 45650.0 True False 37628.60769627762 42028.519566905576 41454.41131538757 38299.826349440766 48693.702733597514 57932.763210941754 36613.75680355739 36630.56735956563 41033.387741252845 53925.983634798846 0.6977825003825353 0.7793741853933334 0.7687279586057791 0.7102295362624707 0.9029729167921028 1.0743014648240428 0.6789631701762833 0.6792749040543722 0.7609205243086876 1.0 15.718692966597745 -6.248215079925559 24.70003327931817 0.8360919263466841 0.7440317631380107 0.1593122885649204 0.12171896000641638 1695.392532476129 3166610.807512035 0.039026083428232924 0.05008194957217027 5.646572647882026e-07 6.248215079925559 -0.09206016320867338 LIHEQEQQSS(ph)S ddPTM_PC-9_Lapatinib_30min_R1 3 LIHEQEQQSSS 11 0 Q96FQ6 Q96FQ6 S100A16 Protein S100-A16 1 LIHEQEQQS(0.001)S(0.619)S(0.38);LIHEQEQQSS(0.593)S(0.407);LIHEQEQQS(0.145)S(0.492)S(0.363) 97.59700000000001 0.0053246000000000005 58634500.0 251482.0 193076.0 244048.0 198874.0 198822.0 228937.0 162514.0 167753.0 236208.0 163935.0 True False 247895.82056384956 192628.94438455362 223983.31549252302 213499.8573842158 187127.6808590919 219145.89818821292 170928.179732891 175547.41679243537 209603.7676594893 192270.9463203429 1.289304626143723 1.0018619457128706 1.1649358354919839 1.1104114348535186 0.9732499082171168 1.1397764580775176 0.8889964032740928 0.9130210265879463 1.0901478963455464 1.0 17.552781250810447 -1.5228787452803672 0.3351498284898707 0.9776609608712086 3.5971083025926514 0.3965546483689518 0.09147903212621543 62.81905624900635 0.8923625478980257 0.08111794819127294 102.46416836151748 0.029999999999997955 1.5228787452803672 2.619447341721443 LIHPDEDISLEER ddPTM_PC-9_AZD4547_30min_R2 4 LIHPDEDISLEER 13 0 J3KS31;J3QRS9;X6R4W8;O43670-3;O43670-2;O43670;O43670-4 J3KS31 ZNF207 BUB3-interacting and GLEBS motif-containing protein ZNF207 0 ;;; 142.97 4.6442e-05 11352700.0 45459.0 44169.5 63665.0 80613.0 67660.0 62048.0 56598.0 70050.0 54743.0 64662.0 False True 59914.0163940603 58446.42709335053 62820.76050202798 62028.91830843455 58266.576896612714 58168.12875126742 61635.11235514575 59225.38208886232 57636.6032199505 62398.20306158103 0.960188169760769 0.9366684331545497 1.0067719488657378 0.9940818046830286 0.9337861354614524 0.9322083953901856 0.9877706300983992 0.9491520457794684 0.9236901127275846 1.0 15.929216862619764 -6.263662325261994 24.995367389392555 0.9524476521980955 0.9740408173439736 0.10273784938229691 0.028576624974380287 465.15006809909113 5230253.37206772 0.008964432208966056 0.010618813829448856 5.449261817992806e-07 6.263662325261994 0.021593165145878168 LIHPDEDISLEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LIHPDEDISLEER 13 0 J3KS31;J3QRS9;X6R4W8;O43670-3;O43670-2;O43670;O43670-4 J3KS31 ZNF207 BUB3-interacting and GLEBS motif-containing protein ZNF207 0 ;; 190.78 1.2437e-05 7677600.0 34735.2 37801.0 45670.0 47758.0 46182.0 38211.7 41843.0 37377.8 40231.0 32155.0 False True 40615.18330852807 41553.633461894155 46758.94600443948 45082.27409352507 37132.968620260894 36207.81118414667 37879.32812291388 36396.67235505274 40819.30226542563 37984.446961160036 1.0692582506218404 1.093964419289392 1.231002416653626 1.1868614051330726 0.9775835003792527 0.9532272832922901 0.9972325821051536 0.9581993491248976 1.074632001544324 1.0 15.213121195864927 -6.267464030363743 24.995614149072956 0.989564162440146 1.1477304524867071 0.6684841816246334 0.052312554478479045 299.261143308564 1241600.0125608728 0.017049217049483357 0.019836628331776417 5.401768520594646e-07 6.267464030363743 0.15816629004656113 LIHPDEDISLEER ddPTM_PC-9_Lapatinib_30min_R1 4 LIHPDEDISLEER 13 0 J3KS31;J3QRS9;X6R4W8;O43670-3;O43670-2;O43670;O43670-4 J3KS31 ZNF207 BUB3-interacting and GLEBS motif-containing protein ZNF207 0 ;;; 168.83 0.00012376 5241600.0 45963.299999999996 48903.299999999996 55586.6 46392.200000000004 57636.8 57357.2 48890.7 44080.2 61724.0 45215.0 False True 45307.85491336308 48790.0674134598 51016.48431848108 49804.03714784243 54246.716742308694 54904.16626216363 51422.02122196765 46128.32701468169 54771.99313746498 53030.35250479959 0.854375895564006 0.9200404128757014 0.962024235344537 0.9391609671712976 1.0229371327938845 1.03533474074483 0.9696714955329331 0.8698476407545428 1.032842335575796 1.0 15.694530717981644 -4.659685863704186 1.073927247218087 0.9801125861315072 0.766820973597528 0.4274488551194904 0.04661431288481495 2.3241693149727842 1.8556556336927508 0.01553061605803872 0.6027601398098561 2.1893446602899395e-05 4.659685863704186 -0.2132916125339792 LIHTLDDR ddPTM_PC-9_AZD4547_30min_R2 2 LIHTLDDR 8 0 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;H7C3A1 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 0 ; 143.89 0.0014177999999999999 6235400.0 27804.0 31711.0 48164.0 65477.0 51668.0 44777.0 42553.0 49920.0 37742.0 45917.0 False True 36645.09364087315 41960.960607596586 47525.31389020144 50382.28925956575 44494.79005459928 41977.08711151854 46340.134563915984 42206.011047480475 39736.96506817988 44309.45980604705 0.8270264138014176 0.9469977921479882 1.072577144885786 1.1370549196514899 1.0041826338972188 0.947361743863774 1.0458293729320483 0.9525282238200631 0.8968054506220103 1.0 15.435327118021071 -10.307452922307125 14.808860257003852 0.9999999998527092 0.9881653799430516 0.0 0.08474505684724883 0.0 0.0 0.08754619331695837 0.02123307071568014 4.926597449655241e-11 10.307452922307125 -0.011834619909657507 LIHTLDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LIHTLDDR 8 0 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;H7C3A1 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 0 98.62899999999999 0.0045721 2324900.0 6532.9 7946.7 7991.8 7963.3 8967.7 8187.5 8102.6 7981.5 6353.5 7297.5 False True 7638.790939343463 8735.595858089308 8182.354821070274 7517.142118366941 7210.543560173088 7758.133086729998 7335.063070256008 7771.994082098281 6446.407917858901 8620.478983021785 0.8861214039716613 1.0133538838496385 0.9491763551869442 0.8720097958793369 0.8364434939606494 0.8999654313884187 0.8508881101273571 0.9015733461453113 0.7478015932241395 1.0 13.073552317228428 -5.755363211765862 5.3544401395531125 0.866926695477012 0.956996448791992 0.21716382088237907 0.06602125951091027 0.21537147992094519 18.5823604140367 0.017175694729848943 0.028304211446238972 1.7564540313491434e-06 5.755363211765862 0.09006975331498002 LIHTLDDR ddPTM_PC-9_Lapatinib_30min_R1 2 LIHTLDDR 8 0 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;H7C3A1 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 0 ; 151.04 0.00038381 7742800.0 53309.0 41541.0 47837.0 42620.0 40372.0 40640.0 36377.0 38860.0 48613.0 36654.0 False True 52548.80388432673 41444.81436677142 43904.02651616005 45754.41697615211 37997.39833440591 38901.92193646712 38260.423065972 40665.57746540464 43137.69202241567 42989.59506161505 1.2223609877927646 0.9640661724626722 1.0212709948357128 1.0643137463978054 0.8838743021409239 0.9049148260343172 0.8899926368493366 0.9459399979720791 1.0034449489600532 1.0 15.391699900539395 -1.5228787524224177 0.94129380509111 0.9481440301449932 171.31236225719834 0.621254047701853 0.05899412511078043 770.9852250049669 1.4070506900662543 0.020047365149819002 282701.86392232374 0.02999999950664259 1.5228787524224177 170.36421822705336 LIIES(ph)PSNTSSTEPA ddPTM_PC-9_Lapatinib_30min_R1 2 LIIESPSNTSSTEPA 15 0 P38432 P38432 COIL Coilin 1 LIIES(0.5)PS(0.5)NT(0.001)SSTEPA;LIIES(0.812)PS(0.188)NTSSTEPA 162.31 8.007899999999999e-05 3623700.0 21820.2 19089.0 23350.7 18751.7 20087.8 20364.8 17465.1 16562.0 19701.8 15029.0 True False 21509.039946665398 19044.800593324664 21430.895582308633 20130.762571837455 18906.27509813431 19493.84497666745 18369.357420609387 17331.530982553573 17482.77581484848 17626.74262511628 1.220250411781542 1.080449235480854 1.2158171273103988 1.1420580081060017 1.0725904099373884 1.1059244121991514 1.0421300073012332 0.9832520591670715 0.9918324778814968 1.0 14.10547827265437 -6.996143096571111 0.7958828320686686 0.9824263074885256 1.1677884451019713 0.7484012693909787 0.04116994506091907 0.317560377220577 0.4202088077684765 0.02983978251314129 0.02272232689826927 1.0089204000717074e-07 6.996143096571111 0.18536213761344578 LIIESPS(ph)NTSSTEPA ddPTM_PC-9_AZD4547_30min_R2 3 LIIESPSNTSSTEPA 15 0 P38432 P38432 COIL Coilin 1 LIIES(0.269)PS(0.731)NTSSTEPA;LIIES(0.052)PS(0.948)NTSSTEPA;LIIES(0.058)PS(0.942)NTSSTEPA 215.53 1.0563e-17 12051000.0 42549.9 46126.4 60238.6 72574.0 64842.9 56553.2 51436.9 69172.6 50732.7 57616.5 True False 56079.88310709929 61035.856749085266 59439.79680479794 55843.18555712273 55840.58260492709 53016.91946390178 56014.684453521215 58483.56409821612 53414.32694914021 55599.36387209771 1.0086425311646907 1.0977797675796042 1.0690733250390214 1.0043853322780079 1.0043385160554046 0.9535526267146391 1.0074698800939328 1.0518746982924716 0.960700325133503 1.0 15.762780756314418 -5.7941334060572975 6.4052437342098605 0.9982173365093953 1.062511088395239 0.42272168626735673 0.032593715259854265 0.16036248392744953 19.423901254476366 0.009161731942861096 0.014062412460913502 1.6064477105357304e-06 5.7941334060572975 0.06429375188584363 LIIESPS(ph)NTSSTEPA ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LIIESPSNTSSTEPA 15 0 P38432 P38432 COIL Coilin 1 LIIES(0.116)PS(0.884)NTSSTEPA;LIIES(0.074)PS(0.926)NTSSTEPA;LIIES(0.367)PS(0.633)NTSSTEPA 188.15 2.7666e-07 12984400.0 39063.1 38871.8 47687.9 48626.0 47841.6 49029.0 50757.3 43571.1 41588.0 38329.9 True False 45675.711298606715 42730.73540922346 48824.96039336789 45901.64286761904 38467.381913799174 46457.832929378324 45949.20109297082 42427.404792396504 42196.14582323383 45278.80745067853 1.0087657752108539 0.9437248420415966 1.0783181612402697 1.0137555614206262 0.8495670288070434 1.0260392343589015 1.0148059032478394 0.9370256678825296 0.9319182239770207 1.0 15.466548340642193 LIIESPS(ph)NTSSTEPA ddPTM_PC-9_Lapatinib_30min_R1 2 LIIESPSNTSSTEPA 15 0 P38432 P38432 COIL Coilin 1 LIIES(0.39)PS(0.61)NTSSTEPA;LIIES(0.239)PS(0.761)NTSSTEPA 198.32 7.4516e-10 15609200.0 70655.0 58492.0 69658.0 67185.0 64813.0 62586.0 52877.0 57639.0 63169.0 54652.0 True False 69647.44674345976 58356.565367737734 63930.98812765588 72126.00902258995 61000.82676726068 59909.34267509177 55614.712330851915 60317.11836151465 56054.24202094038 64098.525380787476 1.0865686274326598 0.9104197798788862 0.9973862541745491 1.125236635228563 0.9516728568227674 0.9346446321376475 0.8676441774668587 0.941006333658867 0.8745012726570736 1.0 15.968003546841263 -6.507794055490054 22.16475886778552 0.9193531087573735 1.0214718586371658 0.3865813152413673 0.0630947806004526 168.9080159694546 248186.5566823702 0.01987075505285419 0.021741527721066616 3.106032134174936e-07 6.507794055490054 0.1021187498797923 LIINSLYK ddPTM_PC-9_Lapatinib_30min_R1 1 LIINSLYK 8 0 P14625;Q96GW1;A0A1W2PRR1;F8W026 P14625 HSP90B1 Endoplasmin 0 111.74 0.017237 2353000.0 31641.0 28843.0 33940.0 22314.0 26624.0 28838.0 25057.0 25179.0 31346.0 26761.0 False True 31189.79353775125 28776.215805608626 31149.584212188725 23955.045997321893 25058.028664797956 27604.665964661384 26354.328855157397 26348.90826045865 27815.483391986552 31386.603193208928 0.9937295012701387 0.9168311597297949 0.9924484029201515 0.7632251840015937 0.798367013803511 0.879504729923567 0.8396680804522244 0.8394953763636239 0.8862215264506529 1.0 14.937861281630246 -5.742700009937235 24.999935799334253 0.849020025081167 0.962585865262965 0.38553376579447785 0.06258442381020152 235.19003910244032 313761.35589863063 0.0162739608268229 0.02812606859399557 1.8084228675573915e-06 5.742700009937235 0.11356584018179794 LIIWS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 1 LIIWSPVR 8 0 H0YJK8;A0A087WTS0;P18283 H0YJK8 GPX2 Glutathione peroxidase;Glutathione peroxidase 2 1 LIIWS(1)PVR 83.78299999999999 0.014566999999999998 1378100.0 4207.1 7734.4 7731.7 9439.5 8629.5 6712.6 6926.8 9131.1 8265.5 6274.9 True False 5544.870286883814 10234.393545564475 7629.172606196967 7263.369113821201 7431.442881012701 6292.860060852207 7543.271781010345 7720.098306803867 8702.39745564731 6055.2176609309145 0.9157177491174378 1.6901776482120816 1.259933669341306 1.1995223822729681 1.2272792320846497 1.0392458889553375 1.2457474203909396 1.2749497605370965 1.437173350810551 1.0 12.563963104648034 -11.790645771287867 2.1901155865384596 0.00019854604535384733 1.2590028621124667 0.12994851962259768 0.19717237280015829 5792236.227053439 737136.21479909 28788713.334351987 0.050809365975058585 1.6194003496575605e-12 11.790645771287867 1.258804316067113 LIKNNAS(ph)T(ph)DY(ph)DLS(ph)DK ddPTM_PC-9_Lapatinib_30min_R1 1 LIKNNASTDYDLSDK 15 1 P39023;G5E9G0;B5MCW2 P39023 RPL3 60S ribosomal protein L3 4 LIKNNAS(1)T(1)DY(1)DLS(1)DK 47.201 0.031366000000000005 2050900.0 5106.6 16631.0 10123.0 11776.0 15614.0 13138.0 16504.0 16101.0 11395.0 12324.0 True False 5033.778947564254 16592.491941305587 9290.72601591003 12642.046323584404 14695.615218305105 12576.118366173838 17358.496365307798 16849.11123959033 10111.575105330405 14454.18697930222 0.3482574948540801 1.1479367165420877 0.6427705708535495 0.874628669304422 1.016702996809755 0.8700675025293573 1.200932047590392 1.165690693203121 0.6995602810320463 1.0 13.819199841777344 -4.750162923591389 24.993303590289162 0.9570518980389481 0.3482561678723834 0.5074951283980634 0.1800783642634087 427.4036510329187 947243.2799926989 0.04502343100765823 0.6835599532246859 1.7776124217565796e-05 4.750162923591389 -0.6087957301665647 LILDSAR ddPTM_PC-9_AZD4547_30min_R2 1 LILDSAR 7 0 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 118.69 0.031406 6027600.0 50230.0 56219.0 56313.0 74662.0 64167.0 57476.0 56358.0 62906.0 51797.0 53770.0 False True 66202.09515109561 74390.69232753536 55566.25282573947 57449.82941640115 55258.519653043906 53882.01663402277 61373.752820087335 53185.32313607389 54534.88367432872 51887.52866631427 1.2758768215159657 1.4336911824407297 1.070898041475108 1.1071991843330546 1.0649672681157796 1.0384386772500758 1.182822816919619 1.0250116839849062 1.0510210271342741 1.0 15.663100203424596 -5.2712033415043384 24.915736139773557 1.0728398362885743 1.3547840016465227 0.7899230064091928 0.0592012984896875 228.33816184957777 582675.5310278714 0.01470290272041496 0.031209061121793162 5.355458502819644e-06 5.2712033415043384 0.2819441653579484 LILDSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LILDSAR 7 0 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 ; 123.99 0.021457 8604400.0 58880.0 75261.0 72899.0 83875.0 83823.0 63867.0 77775.0 66402.0 68737.0 57175.0 False True 68847.22106699068 82732.41469737882 74637.18863099697 79175.7556764188 67398.48487844033 60517.70208857216 70407.58895776169 64659.01785873456 69742.148587372 67540.37490294901 1.0193491103050512 1.2249327134511727 1.1050751308124305 1.172272966950347 0.9978991821601143 0.8960225964918322 1.042451852820371 0.9573387466629438 1.0325993701928184 1.0 16.043462567025195 -6.309727019288098 7.030988782240042 0.983179955485295 1.135262589715805 0.5588234713358956 0.06199737344336177 0.16776055062004633 20.68810355503398 0.018185481556109374 0.020769593888547166 4.900867721620961e-07 6.309727019288098 0.15208263423051005 LILDSAR ddPTM_PC-9_Lapatinib_30min_R1 1 LILDSAR 7 0 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 123.99 0.021457 15342000.0 72603.0 75710.0 77488.0 73308.0 72344.0 77321.0 76080.0 68691.0 61730.0 59303.0 False True 71567.66790624041 75534.69814660867 71117.2357523298 78699.31486831924 68088.86815377644 74014.16107405449 80019.05013770108 71882.63462882423 54777.31735428219 69553.44453371942 1.0289593619126154 1.0859950740468296 1.0224833037255583 1.1314941394479163 0.9789431509861031 1.064133653915192 1.150468545075549 1.0334877749149523 0.7875572190781467 1.0 16.085834343470978 -8.090640194067207 7.260735341095305 0.8960823762616292 1.0661670560341754 0.5048008640260164 0.06729196928497004 0.2032290957873747 14.112219149457573 0.04285268063474855 0.016051189183094783 8.116332043270079e-09 8.090640194067207 0.17008467977254615 LILFPR ddPTM_PC-9_Lapatinib_30min_R1 1 LILFPR 6 0 P26373 P26373 RPL13 60S ribosomal protein L13 0 130.51 0.04 8415300.0 14204.0 12822.0 12249.0 13791.0 12501.0 12515.0 10136.0 11875.0 10179.0 9876.6 False True 14001.448355305409 12792.311446781332 11241.934502507345 14805.236145427363 11765.715757911632 11979.7626238899 10660.792484171101 12426.75585181885 9032.533830378077 11583.757150257732 1.2087139063506598 1.1043318053760054 0.9704912108121343 1.278103119167856 1.0157080820405364 1.0341862720786887 0.9203225124530433 1.07277420362204 0.77975856306493 1.0 13.499815641762815 -6.776856407242993 1.8018355454326798 0.949961310561804 1.12516515158878 0.3894968925869281 0.10466827878930457 0.38599234331879273 2.5888796424376093 0.04240206366957445 0.0383193913596283 1.6716432259414004e-07 6.776856407242993 0.17520384102697595 LINGVRS(ph)PQTR ddPTM_PC-9_AZD4547_30min_R2 1 LINGVRSPQTR 11 1 Q92615;H0Y4V9 Q92615 LARP4B La-related protein 4B 1 LINGVRS(0.999)PQT(0.001)R 74.133 0.010935 5219500.0 8265.1 6912.4 14591.0 23447.0 19344.0 13390.0 11264.0 16774.0 10268.0 15754.0 True False 10893.229875240284 9146.698120650579 14397.513806409956 18041.65640253887 16658.419501745146 12552.721183268932 12266.47417874061 14181.963728173829 10810.745517462532 15202.4572551444 0.7165440226154292 0.6016591901651559 0.9470517538563012 1.1867592258109263 1.0957715073402399 0.8257034354772603 0.806874439629799 0.9328731197961274 0.711118297261073 1.0 13.892016912645364 -5.268045226261132 24.500381655187716 0.9416584783031259 0.6591015984637408 0.4108265024875739 0.13367705945917518 371.14113324915024 1376529.5937782668 0.038307170370359946 0.08291058052444093 5.394544422529309e-06 5.268045226261132 -0.28255687983938504 LIPDGCGVK ddPTM_PC-9_Lapatinib_30min_R1 2 LIPDGCGVK 9 0 F8W7C6;A0A087WV22;X1WI28;P27635 F8W7C6 RPL10 60S ribosomal protein L10 0 ; 94.11399999999999 0.026958999999999997 15058200.0 191708.0 187993.0 195147.0 202480.0 213310.0 198327.0 209108.0 179907.0 189985.0 194518.0 False True 188974.20876505837 187557.7137587557 179102.766949204 217371.05465347975 200763.52518359548 189845.0165328176 219934.5890666981 188266.1360027934 168586.88866925825 228140.17712105732 0.828324984883235 0.8221161047807574 0.7850557898627705 0.9527960282863146 0.880000742162416 0.8321419704696763 0.9640326918392584 0.8252213107684857 0.738961855805878 1.0 17.799561012402634 -5.730499544993384 24.999977291572755 0.8783692687489355 0.8128606671242978 0.1698009171266035 0.07291659696875914 407.30106459259747 329104.1210185534 0.01971199368911267 0.03413756630859365 1.8599465118716166e-06 5.730499544993384 -0.06550860162463767 LIPGPLS(ph)PVAR ddPTM_PC-9_AZD4547_30min_R2 5 LIPGPLSPVAR 11 0 P48634;P48634-2;P48634-3 P48634 PRRC2A Protein PRRC2A 1 LIPGPLS(1)PVAR;LIPGPLS(1)PVAR;LIPGPLS(1)PVAR;LIPGPLS(1)PVAR;LIPGPLS(1)PVAR 160.72 0.00022626 600613880.0 356024.9 328407.8 427635.0 618675.0 479703.0 384428.0 322101.0 463456.0 310391.1 369631.0 True False 469233.4124220432 434559.1989854452 421964.2804882545 476049.0371834662 413104.5187265121 360389.6563884777 350767.3650076828 391839.52435939695 326797.73987001006 356690.33119692095 1.3155204147179131 1.2183094437329576 1.182998930955875 1.3346283752240256 1.1581601254519178 1.0103712516656764 0.9833946544910179 1.0985426014900048 0.916194556699638 1.0 18.444312583644084 -6.6203172159363355 3.341973541160454 1.0058912073983872 1.2540942620589053 0.8152695797814203 0.058684544438878064 0.10235514502200029 2.2655276491344667 0.019821390355552665 0.0198852723211667 2.3970814111710236e-07 6.6203172159363355 0.24820305466051806 LIPGPLS(ph)PVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LIPGPLSPVAR 11 0 P48634;P48634-2;P48634-3 P48634 PRRC2A Protein PRRC2A 1 LIPGPLS(1)PVAR;LIPGPLS(1)PVAR;LIPGPLS(1)PVAR;LIPGPLS(1)PVAR;LIPGPLS(1)PVAR;LIPGPLS(1)PVAR 122.55 0.00065845 485224000.0 250875.0 243309.0 270824.0 288779.0 301512.0 287962.0 327795.0 296588.0 289461.0 228815.0 True False 293343.1824928889 267463.1095468371 277281.4712657392 272599.6488641507 242432.8880220024 272860.765791871 296743.8845697148 288802.87926096213 293693.8195185897 270297.34820145665 1.085261044715303 0.9895143675160766 1.025838666604591 1.008517659081798 0.8969118255696447 1.00948369492883 1.097842381896204 1.0684636056647994 1.0865582717433666 1.0 18.044187832571446 -7.153826783744529 6.387243887965334 1.0686076537209053 0.9978273321357723 0.2594237113176995 0.04972413697254312 0.30685812908056614 15.711764040656657 0.019421958980186137 0.015004285212706213 7.01735126276396e-08 7.153826783744529 -0.07078032158513292 LIPGPLS(ph)PVAR ddPTM_PC-9_Lapatinib_30min_R1 6 LIPGPLSPVAR 11 0 P48634;P48634-2;P48634-3 P48634 PRRC2A Protein PRRC2A 1 LIPGPLS(1)PVAR;LIPGPLS(1)PVAR;LIPGPLS(1)PVAR;LIPGPLS(1)PVAR;LIPGPLS(1)PVAR;LIPGPLS(1)PVAR 137.01 8.7106e-05 443648600.0 250303.0 191642.0 239673.0 181500.0 222345.0 215815.0 212114.0 209126.0 230644.0 180760.0 True False 246733.6333200521 191198.26472344907 219968.0111045344 194848.11546625136 209267.1042470892 206585.09553933694 223096.22503822722 218842.7574119974 204666.44393100712 212004.12515243966 1.1638152471921972 0.9018610585335057 1.0375647688287593 0.9190770006298112 0.9870897752419562 0.9744390369328605 1.0523202078158238 1.0322570716708481 0.9653889695959621 1.0 17.693732811296357 -7.217466084227167 24.981725869093264 1.015179786982126 0.9907787890865486 0.0053610854111294515 0.0705969179640239 2119.571275502169 1204153.3377900168 0.02552586657434406 0.0197719909882683 6.060855302938395e-08 7.217466084227167 -0.02440099789557737 LIPIT(ph)GGNARSPEDQLGK ddPTM_PC-9_AZD4547_30min_R2 1 LIPITGGNARSPEDQLGK 18 1 Q9UK61-3;Q9UK61;Q9UK61-2 Q9UK61-3 FAM208A Protein FAM208A 1 LIPIT(0.5)GGNARS(0.5)PEDQLGK 52.522 0.039297000000000006 9340400.0 30649.0 23647.0 37669.0 67254.0 60264.0 34386.0 28842.0 37504.0 29083.0 46347.0 True False 40394.74446119701 31290.43030771141 37169.484447512645 51749.6293639421 51897.38383235984 32235.83798415874 31408.88212564247 31708.618556184065 30620.26800587873 44724.40563692887 0.9031924267282636 0.699627638692977 0.8310783322477933 1.1570780791150976 1.1603817444475608 0.7207661572039241 0.7022761214675195 0.7089779753272408 0.6846433746812194 1.0 15.448774689320139 -6.849264665141052 24.999866714226567 0.7413244372521429 0.9412762527061281 0.26073809679389015 0.1548181374920898 31.50569342642174 8961.478010744724 0.05928284036380935 0.052282560830079934 1.414931238243735e-07 6.849264665141052 0.19995181545398522 LIPNATGT(ph)GTFSPGASPGSEAR ddPTM_PC-9_Lapatinib_30min_R1 1 LIPNATGTGTFSPGASPGSEAR 22 0 Q16512;Q16512-2;Q16512-3;K7EN76 Q16512 PKN1 Serine/threonine-protein kinase N1 1 LIPNAT(0.128)GT(0.595)GT(0.261)FS(0.017)PGASPGSEAR 188.54 3.3455999999999998e-15 6018800.0 18142.0 17398.0 22289.0 17285.0 16607.0 18658.0 15582.0 17147.0 20033.0 14654.0 True False 17883.291753164656 17357.715999929926 20456.484458028124 18556.196561069683 15630.20891061823 17860.040833922332 16388.759716688455 17943.712218201064 17776.67258315786 17186.924374772385 1.040517277158351 1.0099373000912388 1.1902353214548917 1.0796694135867129 0.9094244304443929 1.0391644510950413 0.9535597736581941 1.044032767406571 1.0343137722332174 1.0 14.069023775077431 -6.053103667124663 24.985258936337527 0.9985152483145892 1.0834927230638198 0.33081829587563394 0.057980497647647934 383.83778613711183 180594.69570137435 0.017360825143043785 0.022412837036776764 8.849043558462549e-07 6.053103667124663 0.08497747474923067 LIPNATGTGT(ph)FSPGASPGSEAR ddPTM_PC-9_AZD4547_30min_R2 1 LIPNATGTGTFSPGASPGSEAR 22 0 Q16512;Q16512-2;Q16512-3;K7EN76 Q16512 PKN1 Serine/threonine-protein kinase N1 1 LIPNAT(0.015)GT(0.185)GT(0.688)FS(0.107)PGAS(0.005)PGSEAR 123.0 1.3896e-06 6899700.0 11107.0 6753.3 15750.0 19010.0 14861.0 16980.0 16068.0 16979.0 13902.0 14067.0 True False 14638.794960048139 8936.172157020661 15541.144709132808 14627.53820157222 12797.80666953239 15918.237915751035 17498.02087215947 14355.285688605194 14636.831338504491 13574.518611661573 1.0784025112663862 0.6583049029336326 1.1448763049160173 1.0775732547160841 0.9427816216287828 1.1726557951068721 1.289034357146728 1.0575171097612905 1.0782578562992509 1.0 13.728613416703743 -5.2925883324800775 24.979575669711824 1.1009875544625534 0.8683535750445992 0.3273715327913628 0.12994127589435547 627.4344926211054 503163.40010687325 0.03333536522721877 0.0694042527265678 5.09813894425113e-06 5.2925883324800775 -0.23263397941795416 LIPNATGTGT(ph)FSPGASPGSEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LIPNATGTGTFSPGASPGSEAR 22 0 Q16512;Q16512-2;Q16512-3;K7EN76 Q16512 PKN1 Serine/threonine-protein kinase N1 1 LIPNATGT(0.001)GT(0.696)FS(0.301)PGAS(0.002)PGSEAR;LIPNAT(0.019)GT(0.032)GT(0.853)FS(0.096)PGASPGSEAR;LIPNATGT(0.001)GT(0.851)FS(0.147)PGASPGSEAR;LIPNATGT(0.006)GT(0.744)FS(0.227)PGAS(0.021)PGS(0.001)EAR 215.88 1.5803999999999998e-93 16194100.0 66486.1 61274.4 69520.0 68869.0 72068.0 68492.7 80144.0 67421.0 63416.0 54161.0 True False 77740.88356966797 67357.31748359792 71177.62045606808 65010.49320631056 57946.79274446674 64900.82223749276 72552.18012768724 65651.2701884544 64343.3390287149 63979.960561759945 1.2150817675891592 1.0527877305985176 1.1124986610043346 1.0161071159704114 0.9057022266922252 1.0143929703558336 1.1339828829317975 1.0261223922618885 1.0056795669107077 1.0 15.96533248270371 LIPNATGTGT(ph)FSPGASPGSEAR ddPTM_PC-9_Lapatinib_30min_R1 2 LIPNATGTGTFSPGASPGSEAR 22 0 Q16512;Q16512-2;Q16512-3;K7EN76 Q16512 PKN1 Serine/threonine-protein kinase N1 1 LIPNAT(0.003)GT(0.132)GT(0.806)FS(0.058)PGASPGSEAR;LIPNATGT(0.006)GT(0.584)FS(0.327)PGAS(0.082)PGS(0.001)EAR 189.84 1.059e-52 5065600.0 28530.0 24729.0 27167.0 22385.2 26011.0 22950.1 22466.4 21022.7 29143.0 25393.0 True False 28123.156968238764 24671.74151984523 24933.43412765265 24031.48228283813 24481.084119593583 21968.577722296097 23629.600263060544 21999.491389139534 25860.608450605 29782.14621595435 0.9442958463877642 0.8284071047448062 0.8371940002865127 0.8069090155082382 0.822005369998453 0.7376425313004302 0.7934149571262974 0.7386805245538135 0.8683258843431312 1.0 14.862160103366858 LIPNATGTGTFS(ph)PGASPGSEAR ddPTM_PC-9_AZD4547_30min_R2 1 LIPNATGTGTFSPGASPGSEAR 22 0 Q16512;Q16512-2;Q16512-3;K7EN76 Q16512 PKN1 Serine/threonine-protein kinase N1 1 LIPNAT(0.047)GT(0.255)GT(0.31)FS(0.388)PGASPGSEAR 204.04 9.014700000000001e-25 7747600.0 15293.0 13074.0 18585.0 22319.0 18149.0 14889.0 14108.0 19152.0 13683.0 18516.0 True False 20155.855885839203 17299.914823995397 18338.550756776724 17173.699375112596 15629.324624543668 13957.988476302546 15363.584669182586 16192.498469177617 14406.255445601866 17867.760475831765 1.1280572018581934 0.9682195397344594 1.026348589213615 0.961155674676859 0.8747220809056713 0.7811828737676643 0.8598494864515132 0.9062410754319135 0.8062709070388542 1.0 14.125071199553656 -6.025618010002371 2.052682116567792 0.8605790128386995 1.0383219736380933 0.568753848408413 0.06626529047932417 0.22787210576151873 1.9195974356485679 0.020630212459085584 0.03195096243146586 9.427184135961672e-07 6.025618010002371 0.17774296079939378 LIPSVGS(ph)PASSTPLPPDGTGPNSTPNNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LIPSVGSPASSTPLPPDGTGPNSTPNNR 28 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 LIPS(0.158)VGS(0.711)PAS(0.039)S(0.039)T(0.039)PLPPDGT(0.01)GPNS(0.003)T(0.003)PNNR 75.26100000000001 0.00047013 0.0 4293.7 4836.5 4409.5 4379.6 6354.0 4957.6 4841.0 3775.3 7029.7 3484.1 True False 5020.538605559407 5316.635756685032 4514.639203121876 4134.225210854778 5108.979312570651 4697.614728643986 4382.4254341951155 3676.202375260998 7132.496063614187 4115.739749879575 1.21983869502592 1.2917813272427137 1.0969204754148927 1.0044914066725779 1.2413271059522502 1.141377981632934 1.0647965373231734 0.8932057415361508 1.7329803381817037 1.0 12.006936044000714 -11.575472966674953 2.7353032499016368 0.7627030097442649 1.1704135117637446 0.05926941971767241 0.21458254733666599 46741108.13035247 45504441.96511253 68652837.39316507 0.05071897346640636 2.6578289850403857e-12 11.575472966674953 0.4077105020194798 LIQNLDANHDGR ddPTM_PC-9_AZD4547_30min_R2 4 LIQNLDANHDGR 12 0 Q96FQ6 Q96FQ6 S100A16 Protein S100-A16 0 ;;; 193.49 1.5032000000000001e-05 39467500.0 162225.0 162147.0 214643.0 232930.0 205984.0 201066.0 200678.0 231109.0 184371.0 190208.0 False True 213809.1755103811 214557.84679259433 211796.69357475502 179231.587232626 177386.6771426527 188493.3112348884 218537.95323520107 195396.41440649418 194116.4746591437 183548.87581480946 1.1648623537531364 1.168941219825673 1.1538980701164632 0.9764788067318955 0.9664274779957025 1.026937977136224 1.190625397540945 1.064547050692036 1.057573759563618 1.0 17.485804752800362 -5.661282600080522 7.83726928445108 1.0458382944384692 1.1651094132384736 0.4708202985361486 0.05923024334340615 0.24191788594918107 16.747245111727413 0.01796534064326442 0.03118972664612177 2.1813100480732012e-06 5.661282600080522 0.1192711188000044 LIQNLDANHDGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LIQNLDANHDGR 12 0 Q96FQ6 Q96FQ6 S100A16 Protein S100-A16 0 ;;;;; 193.15 4.7393e-12 26710700.0 162108.0 171363.0 198895.0 176293.0 224021.0 175883.0 196723.0 172655.0 155924.0 136676.0 False True 189549.68262105464 188374.7861413871 203637.4111134881 166415.87475961723 180125.69319820392 166659.38585567422 178087.97328881727 168122.98919309417 158204.09352077282 161454.2768733795 1.1740146268761213 1.166737665853968 1.261269847148061 1.030730668659393 1.1156452259203233 1.03223890430835 1.1030241919728316 1.0413040301493195 0.9798693263780455 1.0 17.30076613243603 -6.200410418947694 0.46499013445527676 1.0011135120135597 1.2296894820522748 0.6134809353391011 0.05295637984331091 1.0616985677545066 0.41999091397672006 0.04620548045168712 0.11617851173849739 6.30361355955374e-07 6.200410418947694 0.2285759700387151 LIQNLDANHDGR ddPTM_PC-9_Lapatinib_30min_R1 4 LIQNLDANHDGR 12 0 Q96FQ6 Q96FQ6 S100A16 Protein S100-A16 0 ;;; 204.32 7.8813e-08 40689700.0 197366.0 258996.0 261804.0 245404.0 269968.0 277225.0 231721.0 253008.0 296805.0 219130.0 False True 194551.52464750796 258396.31067466698 240279.48571266548 263451.82880374615 254089.0130175092 265368.73299303895 243718.37956043906 264763.67533111444 263375.6954047907 257006.32852762865 0.7569911829100867 1.0054083576657487 0.9349166111558805 1.0250791500467842 0.9886488572992247 1.0325377375464564 0.9482971915776731 1.030183485550442 1.024782918434934 1.0 17.971444359237346 -4.760339490712602 24.99988525617792 0.9977883251284176 0.7569908968590338 0.8366428892428058 0.032061160317355515 10.131723468554094 230184.83344372892 0.007750387281238149 0.046274315081144005 1.7364429097892725e-05 4.760339490712602 -0.24079742826938388 LIQYCHSK ddPTM_PC-9_Lapatinib_30min_R1 2 LIQYCHSK 8 0 O60218;C9JRZ8;C9JRZ8-2 O60218 AKR1B10;AKR1B15 Aldo-keto reductase family 1 member B10;Aldo-keto reductase family 1 member B15 0 ; 82.645 0.013576 72117000.0 109328.0 114619.0 98325.0 113760.0 105117.0 105805.0 95000.0 83891.0 97792.0 82773.0 False True 107768.96267170022 114353.60674767033 90241.09804547594 122126.28989223515 98934.22472797341 101279.96679350146 99918.63516143008 87788.88211915252 86777.63516458719 97080.2027619101 1.1101023649075434 1.1779292120775993 0.9295520145007616 1.2579937661620955 1.01909783780129 1.0432607669958345 1.0292380147421123 0.9042923234766556 0.893875709936556 1.0 16.566889501257457 -7.267949096251434 1.2413571082174704 0.9259450249618965 1.1052369350959486 0.3969233859719652 0.0869877033231839 0.45799778902971855 1.3738692118067883 0.05492922826925109 0.03135075511412352 5.3957386237601254e-08 7.267949096251434 0.1792919101340521 LIQYCQSK ddPTM_PC-9_Lapatinib_30min_R1 2 LIQYCQSK 8 0 P15121;E9PCX2 P15121 AKR1B1 Aldose reductase 0 ; 128.69 0.017143000000000002 18078000.0 71768.0 72949.0 81427.0 84319.0 73226.0 72115.0 70427.0 76723.0 77911.0 70193.0 False True 70744.57515936067 72780.09107247306 74732.38637730984 90520.10053993844 68918.99064785511 69030.80955827575 74073.36545804239 80287.83067108203 69135.84274079835 82325.76652370662 0.8593248280171066 0.8840499657117098 0.9077642338840516 1.0995354718485637 0.8371496987885211 0.838507948035899 0.8997591955212726 0.9752454676260105 0.8397837719602637 1.0 16.32905641916451 -10.811455483321966 4.446632000683568 1.0000632804282854 0.9078051095759713 0.12126850852018756 0.07662199600496566 4.909704524850443e-05 7.855248946451624e-06 0.0757772628348858 0.018366087348731873 1.54363464307519e-11 10.811455483321966 -0.09225817085231414 LIRPEYAWIVQPVS(ph)GAVYDRPGASPK ddPTM_PC-9_AZD4547_30min_R2 1 LIRPEYAWIVQPVSGAVYDRPGASPK 26 2 G3V198;Q12769 G3V198 NUP160 Nuclear pore complex protein Nup160 1 LIRPEYAWIVQPVS(0.344)GAVY(0.313)DRPGAS(0.344)PK 70.352 8.2865e-05 3164300.0 34155.0 37254.0 29727.0 34238.0 34751.0 27865.0 31872.0 30049.0 32830.0 29088.0 True False 45015.57953186673 49295.6269583237 29332.80055672325 26344.958071826943 29926.42349592358 26122.597145017826 34708.54625575471 25405.617507326548 34565.32677622663 28069.637973698143 1.603710727371949 1.7561903364950686 1.0450010286633806 0.9385571020371811 1.0661492508013564 0.9306353423401921 1.23651563615738 0.9050924536729743 1.2314133445046598 1.0 14.776722836455873 -5.265890278936833 24.74342894597518 1.0406086305656848 1.6799505645321706 0.8330369347691126 0.11384418415432165 98.57293440689914 547990.1399009528 0.02740665127145829 0.06038063567245024 5.421378399352199e-06 5.265890278936833 0.6393419339664859 LIRPEYAWIVQPVS(ph)GAVYDRPGASPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LIRPEYAWIVQPVSGAVYDRPGASPK 26 2 G3V198;Q12769 G3V198 NUP160 Nuclear pore complex protein Nup160 1 LIRPEYAWIVQPVS(0.341)GAVY(0.318)DRPGAS(0.341)PK 50.215 0.0069574 8360600.0 10593.0 10916.0 8118.2 10062.0 11007.0 9988.6 10042.0 10177.0 9150.7 8560.1 True False 12386.185678713182 11999.668338669257 8311.768676444952 9498.258761444142 8850.257364410632 9464.780232074661 9090.749062215937 9909.864533422819 9284.51167607641 10111.978368285689 1.2249023116544746 1.1866786005302337 0.8219725531171275 0.9393076622111493 0.8752251084879487 0.9359968828413595 0.8990079617582406 0.9800124340161999 0.9181696536451788 1.0 13.303777661942892 -5.213934972968024 8.35705674855181 0.9193106133176095 1.2075894507309208 0.8469262873168691 0.048391878121412914 0.11728433023882567 19.11133712180314 0.011671396188755947 0.03092294549531953 6.1103350827138935e-06 5.213934972968024 0.2882788374133113 LIRPEYAWIVQPVSGAVYDRPGAS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 LIRPEYAWIVQPVSGAVYDRPGASPK 26 2 G3V198;Q12769 G3V198 NUP160 Nuclear pore complex protein Nup160 1 LIRPEYAWIVQPVS(0.312)GAVY(0.271)DRPGAS(0.417)PK 77.681 1.8332e-05 2740800.0 11448.0 11355.0 9023.7 10455.0 9725.3 11155.0 11664.0 9435.2 9008.9 10716.0 True False 15088.225866807503 15025.281690872549 8904.039842019158 8044.761278139807 8375.10996589754 10457.476086584384 12702.073403837932 7977.2066393266805 9485.09206196613 10340.836101696546 1.459091481425964 1.4530045291412617 0.8610560842907409 0.7779604278632712 0.8099064605156536 1.0112795506805006 1.2283410431148787 0.7714276254719787 0.9172461461225538 1.0 13.336065218104144 -5.2574364720101725 24.724745393109437 0.9189488193080577 1.456048088170111 0.7310912675781167 0.12950725080905945 150.57340367794288 930035.3291434952 0.03589836137008226 0.08788193158066958 5.527942640028687e-06 5.2574364720101725 0.5370992688620533 LIRPEYAWIVQPVSGAVYDRPGAS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 LIRPEYAWIVQPVSGAVYDRPGASPK 26 2 G3V198;Q12769 G3V198 NUP160 Nuclear pore complex protein Nup160 1 LIRPEYAWIVQPVS(0.015)GAVY(0.029)DRPGAS(0.957)PK 76.04899999999999 2.2991e-05 9893800.0 30916.0 26207.0 20314.0 26089.0 24271.0 20950.0 24119.0 24902.0 22806.0 21960.0 True False 30475.132170699948 26146.319301653286 18643.86133430764 28007.672090352717 22843.427498621968 20054.017336835288 25367.763804826638 26059.03782922044 20237.348122173324 25755.7567401393 1.1832357510663118 1.0151640879922317 0.723871619165122 1.087433476443109 0.8869251146102578 0.7786227187641479 0.9849356810119273 1.011775273859785 0.7857407695823684 1.0 14.652607308630554 -4.904874255022888 4.044288215931963 0.9093528235206926 1.1779539348194836 0.365265398454827 0.11163922910495838 0.23419694504727862 6.649084151838337 0.027174242526245524 0.14107646786517508 1.2448749988479747e-05 4.904874255022888 0.26860111129879105 LIS(ph)DSVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LISDSVER 8 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 LIS(0.775)DS(0.225)VER 94.40899999999999 0.0067423000000000005 3123700.0 6595.8 7864.1 11286.0 13439.0 16483.0 20447.0 28689.0 30894.0 21561.0 22951.0 True False 7712.338667011838 8644.7958759737 11555.101042393351 12686.056399825864 13253.274474205546 19374.723325113686 25971.370229626864 30083.065234898768 21876.28883559547 27111.83461998397 0.2844639167770343 0.3188569123832613 0.4262013694151172 0.4679158226524091 0.48883724247995514 0.7146223631370447 0.9579348131049576 1.1095916472109462 0.8068907597817299 1.0 14.726635121186831 -6.870302070638123 1.3836912011067195 0.992468673256123 0.3622472134209842 0.9134619312957802 0.08368490693709221 0.11259115241881554 0.44719354045403376 0.04205807474818911 0.03453614163281403 1.348024946656829e-07 6.870302070638123 -0.6302214598351388 down LIS(ph)SSQVDQETGFNR ddPTM_PC-9_Lapatinib_30min_R1 1 LISSSQVDQETGFNR 15 0 O43164-2;O43164 O43164-2 PJA2 E3 ubiquitin-protein ligase Praja-2 1 LIS(0.953)S(0.017)S(0.03)QVDQETGFNR 93.51 0.016728 0.0 8447.3 7662.5 8080.8 7673.0 8847.5 10433.0 6351.6 8088.9 8178.1 7138.5 True False 8326.839952954906 7644.7579520326 7416.4278167900575 8237.298016377643 8327.107444854262 9986.80491051086 6680.4547693825125 8464.739823981261 7256.996258789164 8372.380213546649 0.9945606554611486 0.9130925444192389 0.8858207137786404 0.9838657354630836 0.9945926047864938 1.1928274464114812 0.7979158374309646 1.0110314639420188 0.8667781531286916 1.0 13.031422114619641 -4.419439232889505 19.24728500972564 0.9621023322621407 4.174137752118887 0.00977786441796702 0.10141912239891389 1160.37447266509 215919.6310154504 0.02414769619841461 3.332109120804854 3.806806192563763e-05 4.419439232889505 3.2120354198567465 LISDS(ph)VER ddPTM_PC-9_AZD4547_30min_R2 2 LISDSVER 8 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 LIS(0.013)DS(0.987)VER;LIS(0.004)DS(0.996)VER 96.34200000000001 0.0061493 11706500.0 85592.0 78575.0 122010.0 190492.0 147099.0 138498.0 111886.0 151811.0 94712.0 128398.0 True False 112808.47557580269 103972.83213212782 120392.06768008214 146577.01247206196 126676.84296356514 129837.69816582347 121843.63724809774 128352.09821973304 99718.28296161981 123902.82510130957 0.9104592690567341 0.8391481957502912 0.9716652350876032 1.1829997609191942 1.0223886570785403 1.0478994168184723 0.983380622261614 1.0359093758740812 0.8048104058974024 1.0 16.918849557098405 -5.44648078027425 5.905006498195625 1.0179219207265047 0.8790821609658949 0.26678714198552644 0.08840392084153555 0.2839460025766804 16.933862891246886 0.02358205822383081 0.049511123536537104 3.577002302692085e-06 5.44648078027425 -0.1388397597606098 LISDS(ph)VER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LISDSVER 8 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 LIS(0.001)DS(0.999)VER 99.815 0.0050838 4009900.0 20933.0 30832.0 31982.0 27311.0 35419.0 25903.0 33205.0 33793.0 32457.0 25301.0 True False 24476.54345440412 33892.79719841063 32744.572172410422 25780.85321345667 28478.90120741893 24544.60108037463 30059.58201661821 32905.96955664315 32931.62222238869 29887.871017394194 0.8189457000854701 1.1339983760865953 1.0955806170788707 0.8625858027309032 0.9528581407101473 0.8212227985757206 1.0057451733221172 1.1009807134637484 1.1018390103203766 1.0 14.867272513700318 -7.540947453640429 8.223191013448758 1.0720428569031197 0.9553573765106924 0.21675850779150807 0.10183789055817677 0.3106097995747352 108.84184226112617 0.049641496708505234 0.0291010503163588 2.8777465793226853e-08 7.540947453640429 -0.11668548039242732 LISDS(ph)VER ddPTM_PC-9_Lapatinib_30min_R1 3 LISDSVER 8 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 LISDS(1)VER;LIS(0.01)DS(0.99)VER;LIS(0.001)DS(0.999)VER 131.52 0.0039686999999999995 14742100.0 45607.0 54496.0 65032.0 55661.0 67733.0 72964.0 62964.0 61181.0 77349.0 72271.0 True False 44956.635816700524 54369.81786022427 59685.319990779535 59754.49561965283 63749.0781082016 69843.49980739136 66223.96783478199 64023.69261222134 68637.14109892059 84762.94605494583 0.5303807608050611 0.6414337914232022 0.7041440012253675 0.7049601081694141 0.7520866259990252 0.8239862234391517 0.7812844045304144 0.755326420234607 0.8097540764384001 1.0 16.371146111018355 -3.832286327177581 0.10849608681942807 1.1060097100242277 7.371841986970802e-17 0.8750007792294423 0.04133771984168866 24.252918271960876 0.32262905076317006 0.5742968510463166 4.02386742554883 0.0001471342137473678 3.832286327177581 -1.1060097100242277 LISDS(ph)VERDR ddPTM_PC-9_AZD4547_30min_R2 1 LISDSVERDR 10 1 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 LIS(0.035)DS(0.965)VERDR 69.229 0.018366999999999998 3518900.0 8340.6 9844.0 12228.0 14646.0 13852.0 7518.2 7678.7 12144.0 10850.0 12580.0 True False 10992.73730474272 13025.880490088017 12065.848730366735 11269.59097844433 11928.888902924611 7048.085765500562 8362.08942438703 10267.423841358233 11423.508849285987 12139.578029053993 0.9055287818434458 1.0730093302183001 0.9939265352954774 0.92833465475262 0.9826444440140231 0.5805873769773694 0.6888286729879578 0.8457809502756125 0.9410136680159542 1.0 13.567430654028417 -6.6293905309408885 21.313131489477396 0.7925537314926672 0.9804188562653438 0.32133267807848176 0.11860996342033747 4.050180685082985 793.9581020078094 0.04013573511967265 0.04013567653608089 2.3475209085189364e-07 6.6293905309408885 0.18786512477267658 LISWYDNEFGYSNR ddPTM_PC-9_AZD4547_30min_R2 2 LISWYDNEFGYSNR 14 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 163.71 0.0025521000000000003 25347000.0 23669.2 24299.7 36003.0 54652.0 42892.0 30637.0 27406.0 41125.0 26873.3 29705.9 False True 31195.513250055952 32154.102818467272 35525.5766960577 42052.82576498291 36937.1861698125 28721.263546811824 29845.08090754309 34770.076208486265 28293.767775070686 28665.905482772258 1.0882444745659245 1.1216845334884455 1.2392972103186481 1.466997991403271 1.2885407088225818 1.0019311465347862 1.0411351187032798 1.2129418423354015 0.9870181073496799 1.0 14.807048230358975 -6.758098327891057 24.999596198801438 1.0614472177835654 1.246793041987604 0.4181875678717838 0.11282726649378226 101.2180055839922 757370.4758975254 0.041843644874171054 0.040210534554779936 1.7454269289742931e-07 6.758098327891057 0.18534582420403867 LISWYDNEFGYSNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LISWYDNEFGYSNR 14 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 144.28 0.00013148 16647300.0 32840.0 38747.4 44051.0 43205.2 50687.0 44780.0 40962.0 34497.4 34223.8 31386.0 False True 38399.16338043432 42593.98579935445 45101.342904347795 40784.55271714833 40755.24620967399 42431.65796931534 37081.78282080153 33591.87980301663 34724.258329931465 37076.03334856069 1.0356869360709267 1.148828015093151 1.2164554519718775 1.1000247068968507 1.0992342634532701 1.1444497735344323 1.0001550724746304 0.9060267986926029 0.9365688611691649 1.0 15.17819928223795 -7.40446127173586 3.5430119015806034 0.9418867899163845 1.1272397572194275 0.7342931105793533 0.04872233459306622 0.12425841219488967 2.8421818126836174 0.022907357287050678 0.014511953778127187 3.940385645157827e-08 7.40446127173586 0.18535296730304296 LISWYDNEFGYSNR ddPTM_PC-9_Lapatinib_30min_R1 4 LISWYDNEFGYSNR 14 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ;;; 191.48 6.2259e-06 12133600.0 55338.0 50637.0 63945.0 45628.4 55853.0 64800.0 51746.0 51070.0 62508.0 42468.7 False True 54548.869972253684 50519.75313762803 58687.688934838196 48984.06474788032 52567.83635122293 62028.655056177864 54425.154684877445 53442.89864020114 55467.69080157898 49809.35820901428 1.0951530381771044 1.0142622782978397 1.1782462381580567 0.9834309557318367 1.0553807204387837 1.245321306809213 1.0926692621995644 1.0729489509971095 1.113599789196655 1.0 15.604129201629263 -3.661527651296163 13.830106841771475 1.0887577398855157 1.0750680543350564 0.0 0.07686276989033235 0.0 0.0 0.01730382561960799 0.0 0.00021800795882717883 3.661527651296163 -0.013689685550459352 LIT(ph)SEEER ddPTM_PC-9_AZD4547_30min_R2 1 LITSEEER 8 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 LIT(0.5)S(0.5)EEER 96.03399999999999 0.015267 6944900.0 31310.0 29921.0 38327.0 45372.0 30901.0 37665.0 35910.0 44117.0 30924.0 30990.0 True False 41265.9287115429 39592.37811295441 37818.75893758309 34912.186390412164 26610.929540086145 35309.80159580466 39105.92043311218 37299.731357806406 32558.579507402774 29905.04953262187 1.3798983568486667 1.323936215847599 1.2646278648135514 1.1674344947106097 0.8898473654443427 1.1807304166905668 1.3076694753658094 1.247272013949285 1.0887318368052294 1.0 14.868101486735343 -5.579596480590672 2.5115142404700266 1.1358968515600523 1.3499746349537112 0.40467944848487636 0.11273621424957209 0.33404556844796723 4.222552575375923 0.03519848740216 0.07607697341667158 2.6327130089523314e-06 5.579596480590672 0.2140777833936589 LIT(ph)SEEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LITSEEER 8 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 LIT(0.5)S(0.5)EEER 85.86200000000001 0.02264 0.0 29665.0 33153.0 32938.0 35255.0 39223.0 29657.0 33224.0 31803.0 30778.0 26158.0 True False 34686.69858954276 36444.210739456015 33723.36683806061 33279.77664825218 31537.53471466142 28101.734711835317 30076.78219907012 30968.20494806386 31228.070023744604 30900.238333385932 1.1225382217219266 1.1794151988814967 1.0913626773429916 1.0770071184951118 1.02062431928193 0.9094342382943049 0.9733511397086502 1.0021995498528078 1.0106093579868758 1.0 14.91533034522175 -6.020804284684297 1.5578730375094332 0.9789167748559358 1.1449107814962496 0.8060312519869146 0.03295683406446883 0.16642436366242824 0.8146524929888149 0.012027881625603733 0.020280890397991764 9.532256394927675e-07 6.020804284684297 0.16599400664031383 LITEDVQGK ddPTM_PC-9_Lapatinib_30min_R1 1 LITEDVQGK 9 0 D6RAT0;P61247;D6RG13;D6RB09;E9PFI5;D6RAS7;H0Y8L7;D6RED7;D6RGE0 D6RAT0 RPS3A 40S ribosomal protein S3a 0 125.16 0.0066139 9482300.0 54190.0 50129.0 59138.0 49333.0 53940.0 50412.0 63572.0 53069.0 55239.0 51700.0 False True 53417.24066277108 50012.929380416586 54275.90191928155 52961.11339006367 50767.35525012023 48255.996276111706 66863.44709981502 55534.77947790938 49017.40212754243 60636.27611408025 0.8809452704891149 0.8248021248257884 0.895106121246094 0.8734229208011285 0.8372439487314035 0.795827174236814 1.102697121010846 0.9158672503803997 0.8083841104510074 1.0 15.887893534827652 LITPAVVSER ddPTM_PC-9_Lapatinib_30min_R1 2 LITPAVVSER 10 0 P62851 P62851 RPS25 40S ribosomal protein S25 0 ; 112.41 0.0067044 20496500.0 69706.0 90969.0 86273.0 80632.0 82687.0 81898.0 78227.0 67048.0 83266.0 71104.0 False True 68711.97965748525 90758.36686961858 79179.96696341048 86561.94626046704 77823.51322889673 78395.41345356264 82277.21129234941 70163.2948507578 73887.70625014833 83394.23165987537 0.8239416358882962 1.0883050909297654 0.9494657530552852 1.0379848166658725 0.9332001947844678 0.9400579859443937 0.9866055439891606 0.841344700397503 0.8860050003398371 1.0 16.347659976127083 -7.739810494283625 24.995972440048988 0.8977561021152314 0.9702960452095064 0.09820663280416042 0.07529410451883851 397.66430703540806 459571.8491783616 0.0334054606460401 0.019265453934539524 1.82049506387143e-08 7.739810494283625 0.07253994309427503 LITPPPPPPS(ph)PER ddPTM_PC-9_AZD4547_30min_R2 1 LITPPPPPPSPER 13 0 J3QKY4;J3QR53;Q96HE9 J3QKY4 PRR11 Proline-rich protein 11 1 LITPPPPPPS(1)PER 98.654 0.0027046 9073400.0 29071.0 22341.0 28579.0 31652.0 27953.0 25690.0 23243.0 35510.0 24610.0 26427.0 True False 38314.973285636 29562.2913479334 28200.023786813137 24355.120418525195 24072.208453902087 24083.6002388483 25311.581972342687 30022.74543862244 25910.834357689233 25501.798773752755 1.502441989506676 1.1592237712407891 1.1058052820900415 0.955035393173608 0.9439415888842302 0.9443882940381402 0.9925410437476337 1.1772795207498377 1.0160394797075047 1.0 14.63831139096489 -4.500518560479743 1.3223291801799772 1.0092664076065962 2.027964204815923 0.8284450281181402 0.06749173157914547 1.0793658125070527 1.0353114834037973 0.02183643360234775 1.7702229303014678 3.1585040602857316e-05 4.500518560479743 1.018697797209327 LITPPPPPPS(ph)PER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LITPPPPPPSPER 13 0 J3QKY4;J3QR53;Q96HE9 J3QKY4 PRR11 Proline-rich protein 11 1 LITPPPPPPS(1)PER;LITPPPPPPS(1)PER 134.4 4.6408e-05 12635800.0 39160.0 40205.0 51478.0 35234.0 56672.0 43998.0 38237.0 44342.0 37680.0 31567.0 True False 45789.01455474444 44196.28669441162 52705.430751402186 33259.95321016922 45567.52842335597 41690.66742594766 34614.91454809307 43178.06948423254 38230.998716443464 37289.84721576548 1.2279217527977873 1.1852096480493548 1.4133989460037066 0.8919305305200473 1.221982170098322 1.1180165792774175 0.9282664621231942 1.157904167169063 1.025238813536358 1.0 15.186495265652448 -5.757741099010096 24.999962979327265 1.0606744026238986 1.2664800366880307 0.47150180987872836 0.10926220521652817 88.7987922540217 600258.7250671141 0.029157218560201294 0.048104917209765855 1.7468632203430246e-06 5.757741099010096 0.2058056340641321 LITPPPPPPS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 2 LITPPPPPPSPER 13 0 J3QKY4;J3QR53;Q96HE9 J3QKY4 PRR11 Proline-rich protein 11 1 LIT(0.048)PPPPPPS(0.952)PER;LITPPPPPPS(1)PER 111.66 0.00054115 13329900.0 57199.0 58489.0 53260.0 59430.0 49792.0 48075.0 43515.0 47883.0 57747.0 45910.0 True False 56383.331770988036 58353.57231405345 48881.168389545426 63800.6804526683 46863.33245483849 46018.94431829859 45767.99377946974 50107.81898548564 51242.9247571316 53845.48232877029 1.047132077427074 1.0837227152643487 0.9078044484973928 1.18488455657456 0.8703298852204514 0.8546481956892067 0.849987627560267 0.9305853865239206 0.9516661851824826 1.0 15.716537686337722 -6.29385784192283 24.99964781187843 0.9003436369574734 1.0472970855689072 0.4628697046736915 0.07662895309124568 568.0468087698913 438050.44931461767 0.02309484343061695 0.026189278964165376 5.083258061607913e-07 6.29385784192283 0.14695344861143378 LITS(ph)EEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LITSEEER 8 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 LIT(0.316)S(0.684)EEER 78.264 0.022374 5110200.0 41819.0 45884.0 43707.0 48074.0 54544.0 37702.0 48135.0 37370.0 43715.0 40903.0 True False 48898.1307371006 50439.06028320811 44749.14063972054 45380.56963801091 43856.49474738019 35724.84074942223 43575.30433277874 36389.07709678792 44354.24917434519 48318.39011203017 1.0119983431510498 1.0438895038982259 0.9261306209905995 0.9391987094932658 0.9076563736021687 0.7393632251942013 0.9018368416610282 0.7531102963574914 0.9179579259885565 1.0 15.560284766826634 -5.734431804665647 1.17545751920118 0.8520714800700216 1.0326071357388358 0.3692349045405334 0.07586250659826267 0.4952937908231921 1.3241594551680531 0.02591639018096467 0.07259828894010716 1.843181892917509e-06 5.734431804665647 0.18053565566881413 LITSEEERS(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 1 LITSEEERSPAK 12 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 LIT(0.001)S(0.001)EEERS(0.999)PAK 54.486000000000004 0.039944 24698000.0 57084.0 61125.0 60826.0 67495.0 73659.0 52946.0 73062.0 76435.0 67125.0 69824.0 True False 75235.52457903916 80882.46088547647 60019.40749699761 51935.07053735488 63432.71929689023 49635.278250138705 79564.37646015166 64623.727051565926 70673.09046159657 67379.48301277158 1.1165939721558638 1.2004019216078792 0.8907668152577115 0.7707846397027228 0.9414248441898366 0.7366527024365931 1.1808398180358621 0.9591009631124164 1.048881459185442 1.0 16.040021738585374 -5.261110025713799 24.999987724043635 0.9347913077344636 1.1584979608086194 0.33425009402849715 0.12249519017764363 31.903177633573936 2421399.56643656 0.03261635405712962 0.07615970308506577 5.4813808007160244e-06 5.261110025713799 0.22370665307415583 LITSEEERS(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LITSEEERSPAK 12 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 LITSEEERS(1)PAK 68.786 0.015896 18623000.0 65856.0 85922.0 57963.0 72141.0 72194.0 60933.0 60955.0 41293.0 59518.0 40406.0 True False 77004.12008471004 94451.76832128428 59345.05774590163 68099.17365427774 58048.10394896524 57737.56621358402 55180.90112401634 40209.10250355004 60388.338153006414 47731.28794627999 1.6132839359242865 1.9788229562878477 1.2433156593782375 1.4267198012951408 1.2161436752826886 1.2096377176866833 1.1560740029919294 0.8424055631770104 1.265173029082549 1.0 15.54264764509611 -5.52152687315108 0.6225124973335872 1.0488598922283345 1.9645829743521883 0.6663559596039718 0.17467626229856087 0.9242799508004292 0.4960240152692913 0.09434246469054355 0.5385491077724959 3.0093529512213937e-06 5.52152687315108 0.9157230821238538 LITSEEERS(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 2 LITSEEERSPAK 12 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 LITS(0.001)EEERS(0.998)PAK;LIT(0.002)S(0.002)EEERS(0.996)PAK 60.691 0.027801 53546000.0 212873.0 229662.0 212120.0 209690.0 203911.0 221759.0 210266.0 193661.0 201007.0 180267.0 True False 209837.39198387333 229130.231749391 194680.31240687898 225111.30210533412 191917.35588445075 212274.88451547778 221152.54464056043 202659.19705423937 178367.47496245243 211425.91075932136 0.9924866409715679 1.0837377071073542 0.920796848918367 1.0647290168781236 0.9077286468588122 1.004015466945879 1.0460049283756496 0.958535291754937 0.8436405657275313 1.0 17.689792667776608 -8.000235736699999 24.999447210789683 0.9149094935768514 1.0015730666008722 0.20935905241045116 0.06360318216558218 10.486139316217516 1111967.815759959 0.033209320309952786 0.015677619526065074 9.994573434800487e-09 8.000235736699999 0.08666357302402083 LITSEEERS(ph)PAKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LITSEEERSPAKR 13 2 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 LITS(0.001)EEERS(0.999)PAKR;LIT(0.005)S(0.005)EEERS(0.991)PAKR 65.695 0.012517 71587000.0 106406.0 95539.0 105802.0 146152.0 133093.0 101808.0 116969.0 122668.0 111413.0 102838.0 True False 124418.43418570304 105023.48052474573 108324.72093631938 137963.57727117697 107014.38206609475 96469.00925725885 105888.84953777466 119448.09497748922 113042.20435231207 121481.71533483965 1.0241741635172743 0.8645208888866103 0.8916956814261662 1.135673602326971 0.8809093761240642 0.7941031207154232 0.8716443396103979 0.9832598646492177 0.930528549426012 1.0 16.890379659207234 -4.735373653487409 24.00354164921627 0.9254466412715497 1.0241749526305666 0.09345489580825783 0.08949984861806212 4212.117704484973 3878538.8227853905 0.02332876728290643 1.6703494650130946 1.839188939501099e-05 4.735373653487409 0.09872831135901683 LIVENLSS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 LIVENLSSR 9 0 Q08170;A0A0D9SEM4;B4DJK0;B4DUA4;Q13243-3;Q13243;Q13247-3;Q13247;A0A590UJK4;A0A590UK01;A0A590UJP7;A0A590UK80 Q08170;B4DJK0;Q13247-3 SRSF4;SRSF5;SRSF6 Serine/arginine-rich splicing factor 4;Serine/arginine-rich splicing factor 5;Serine/arginine-rich splicing factor 6 1 LIVENLS(0.015)S(0.985)R 80.87100000000001 0.018058 19490000.0 47501.0 49315.0 66388.0 93759.0 65706.0 64420.0 65139.0 61722.0 58389.0 51341.0 True False 62605.32991782175 65255.1093426138 65507.651742851325 72144.31111210992 56583.856068117566 60391.80721629462 70936.24480903623 52184.28313046057 61475.32333649399 49543.56721698417 1.263641950601406 1.3171257745090974 1.3222231547427707 1.456179180561264 1.1421029862524694 1.2189636436915978 1.4317952621045498 1.0533008836830613 1.240833609482594 1.0 15.59641012825027 -8.658602279235945 0.4527003877889255 0.9858420082661856 1.323944212923917 0.413529352786679 0.10804687359365038 1.333885479105417 0.6483198752939545 0.15249798626351294 0.06923316161162878 2.194813994990986e-09 8.658602279235945 0.33810220465773133 LIVENLSS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LIVENLSSR 9 0 Q08170;A0A0D9SEM4;B4DJK0;B4DUA4;Q13243-3;Q13243;Q13247-3;Q13247;A0A590UJK4;A0A590UK01;A0A590UJP7;A0A590UK80 Q08170;B4DJK0;Q13247-3 SRSF4;SRSF5;SRSF6 Serine/arginine-rich splicing factor 4;Serine/arginine-rich splicing factor 5;Serine/arginine-rich splicing factor 6 1 LIVENLS(0.004)S(0.996)R;LIVENLS(0.026)S(0.974)R;LIVENLS(0.028)S(0.972)R;LIVENLS(0.36)S(0.64)R 108.68 0.0024191 30050000.0 181011.0 168763.0 197685.0 202053.0 153796.0 164992.0 180321.0 182042.0 163371.0 119990.0 True False 211652.5871697871 185516.6753241878 202398.56012453706 190732.6254746645 123660.77783382361 156339.5290681838 163239.6894690138 177263.59038944266 165759.99180743354 141743.23715968276 1.4932111853163548 1.3088220576985374 1.4279239290726953 1.3456206398037325 0.8724280629665025 1.1029769899501969 1.151657692741375 1.2505964583674913 1.1694384517315235 1.0 17.112920377513028 -6.060548777002328 10.8947321728303 1.1073112120950548 1.3977221519447716 0.6656860519827178 0.10535485381453959 0.5370284880565158 95.59345733495998 0.032299093538673745 0.041761155938644386 8.698637304009515e-07 6.060548777002328 0.2904109398497168 LIVENLSS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 2 LIVENLSSR 9 0 Q08170;A0A0D9SEM4;B4DJK0;B4DUA4;Q13243-3;Q13243;Q13247-3;Q13247;A0A590UJK4;A0A590UK01;A0A590UJP7;A0A590UK80 Q08170;B4DJK0;Q13247-3 SRSF4;SRSF5;SRSF6 Serine/arginine-rich splicing factor 4;Serine/arginine-rich splicing factor 5;Serine/arginine-rich splicing factor 6 1 LIVENLS(0.15)S(0.85)R;LIVENLS(0.01)S(0.99)R 116.84 0.0018944000000000003 30990000.0 238148.0 193758.0 220190.0 171697.0 177628.0 190555.0 201636.0 167736.0 176910.0 118042.0 True False 234751.96584900538 193309.3652554558 202086.82815798017 184324.17014440137 167180.27027008435 182405.40685540086 212075.72546747501 175529.6269103737 156984.53285511184 138445.4024189217 1.6956284697607351 1.3962859139989447 1.459686090163442 1.3313852748006407 1.2075537890685157 1.31752592479352 1.5318365345622345 1.2678617263088225 1.1339093253533448 1.0 17.07895761902244 -1.5228787494386204 0.054448527615546576 0.416920426788783 3.138018209568147 0.6289391711975968 0.11587008122573225 310.6260698430299 1.275951504166211 14.065019784296563 69.05008749434614 0.029999999712755996 1.5228787494386204 2.721097782779364 LIVENLSSR ddPTM_PC-9_Lapatinib_30min_R1 2 LIVENLSSR 9 0 Q08170;A0A0D9SEM4;B4DJK0;B4DUA4;Q13243-3;Q13243;Q13247-3;Q13247;A0A590UJK4;A0A590UK01;A0A590UJP7;A0A590UK80 Q08170;B4DJK0;Q13247-3 SRSF4;SRSF5;SRSF6 Serine/arginine-rich splicing factor 4;Serine/arginine-rich splicing factor 5;Serine/arginine-rich splicing factor 6 0 ; 125.71 0.0065321 13321000.0 53800.0 53668.0 50179.0 51045.0 46297.0 53598.0 45490.0 42911.0 44322.0 35906.0 False True 53032.802134288315 53543.735043352106 46053.476316541484 54799.01958112825 43573.901483404086 51305.738483040426 47845.249615720546 44904.801714307236 39329.989628648866 42112.304258262375 1.2593184597321898 1.271451087430033 1.0935871861608204 1.3012591105217606 1.0347071301579265 1.2183075561099062 1.1361346869622642 1.0663107256947826 0.9339310759973999 1.0 15.361954197137136 -7.849299897122563 1.7287960089815109 0.9657011097662501 1.1938278209500064 0.5705464610601216 0.07855200204105116 0.27254423816423123 1.5259057136203076 0.06116877471451781 0.022609914078697346 1.4148164571187344e-08 7.849299897122563 0.22812671118375627 LKATVT(ph)PSPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LKATVTPSPVK 11 1 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 LKAT(0.001)VT(0.503)PS(0.496)PVK 112.08 0.017841 135660000.0 60638.0 50792.0 62402.0 62178.0 69938.0 54944.0 68226.0 73911.0 63744.0 51114.0 True False 70902.81574490786 55834.294087366114 63889.900340902874 58694.36824379581 56234.150954133846 52062.63991661596 61763.13936653496 71970.91456517762 64676.135408199916 60380.56358179864 1.174265550682622 0.9247064084078378 1.0581203047955998 0.9720738721539339 0.9313286862245402 0.8622417021014678 1.0228976959259966 1.1919549983609763 1.0711416318693678 1.0 15.881796602331287 -10.168115952482635 6.923150599031502 0.9999999999482049 1.0173387123393818 0.001723287717837363 0.10089010423912508 0.0 0.0 0.10319543563758357 0.025028569483258007 6.790223159342182e-11 10.168115952482635 0.017338712391176903 LKATVTPS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 2 LKATVTPSPVK 11 1 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 LKATVT(0.001)PS(0.999)PVK;LKATVT(0.009)PS(0.991)PVK 75.911 0.010001999999999999 2165840000.0 4051120.0 3101750.0 4464350.0 4252260.0 4371770.0 4441560.0 4435890.0 3987990.0 3893520.0 4323140.0 True False 5339291.891469358 4104330.029472826 4405149.802045525 3271967.1537620993 3764825.197743198 4163828.5510649793 4830675.616542417 3371737.7803934566 4099323.5184213836 4171788.1844614134 1.279856899580023 0.9838299184891871 1.0559380311908715 0.7843080734417769 0.9024487896499579 0.998092033189489 1.1579388509069444 0.8082236276885076 0.9826298309415762 1.0 21.992234478623665 -4.361840542931936 1.6765030940666952 0.9534942946441772 1.8918398922488202 0.4485307399578131 0.10490515642361904 3.365768354796796 3.616430134676249 0.02933581581280535 7.232490202461808 4.34669789743847e-05 4.361840542931936 0.938345597604643 LKATVTPS(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LKATVTPSPVK 11 1 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 LKATVT(0.031)PS(0.969)PVK 73.80199999999999 0.011244 1111200000.0 511710.0 359850.0 444190.0 571340.0 496020.0 488990.0 598540.0 530770.0 465490.0 464520.0 True False 598332.3962668107 395573.5298342009 454781.1741999552 539329.672109271 398828.44170936337 463346.50358230236 541841.9581456615 516837.8498973015 472296.9106294387 548733.7988617031 1.090387356324679 0.7208842077065075 0.8287828727578949 0.982862133202037 0.7268158851098576 0.8443921342980354 0.9874404661598427 0.9418735477374152 0.8607031526200398 1.0 19.065746914739627 -7.247037565911917 24.095613127849592 0.9426604210978027 0.8564417614034565 0.11513157632444126 0.10900104330837251 1053.194317818924 1762097.3318713622 0.040611764897136894 0.031292873955142866 5.6619031218913586e-08 7.247037565911917 -0.08621865969434617 LKATVTPS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 2 LKATVTPSPVK 11 1 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 LKATVT(0.008)PS(0.992)PVK;LKATVT(0.003)PS(0.997)PVK 81.992 0.0068135 2062120000.0 2594690.0 2699920.0 2347560.0 2436120.0 2431500.0 2175560.0 1955670.0 1994870.0 2210180.0 1702310.0 True False 2557689.2447921303 2693668.5011225836 2154552.6786436597 2615280.391458088 2288483.9505129266 2082516.3702780618 2056925.0234332003 2087558.9428309796 1961246.2541728087 1996552.0153145085 1.2810531482142369 1.3491601924021306 1.0791367628377375 1.3098984506277007 1.1462180463915594 1.0430564063967107 1.030238635234946 1.0455820468579855 0.9823166334406078 1.0 20.929079227700726 -6.469526804343757 0.6935243501109516 0.9915958722649876 1.2975881941261473 0.7158174178571033 0.0693626735941792 0.4136495276817928 0.44120014346320013 0.04647142847232946 0.06596930428603323 3.3921355287830074e-07 6.469526804343757 0.30599232186115977 LKATVTPS(ph)PVKGK ddPTM_PC-9_AZD4547_30min_R2 2 LKATVTPSPVKGK 13 2 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 LKAT(0.001)VT(0.157)PS(0.843)PVKGK;LKAT(0.018)VT(0.153)PS(0.829)PVKGK 142.39 5.3457e-05 6210400.0 111973.0 64902.0 119198.0 188284.0 168527.0 111867.0 96342.0 107601.0 88542.0 129420.0 True False 147578.08481691452 85880.30227221586 117617.35663741047 144878.03275880186 145129.93503776903 104871.93880573164 104916.25136081573 90973.7378749991 93222.14935792441 124889.04519238234 1.1816735774509397 0.6876528052554458 0.9417748086409791 1.1600539705914794 1.1620709791976318 0.8397208789945041 0.8400756943829621 0.7284364912459759 0.7464397635062594 1.0 16.93028740903074 -6.9148319915907965 9.067357813076134 0.8109070733011786 1.0103364501549454 0.28737415601455873 0.15205320997610897 0.40786754529820124 39.36114919727143 0.05601017464429149 0.04939906252044509 1.2166565776665227e-07 6.9148319915907965 0.19942937685376683 LKATVTPS(ph)PVKGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LKATVTPSPVKGK 13 2 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 LKAT(0.005)VT(0.497)PS(0.498)PVKGK;LKAT(0.001)VT(0.058)PS(0.941)PVKGK 102.39 0.023153999999999997 153926200.0 108231.0 35653.3 75900.0 153739.0 122294.0 184254.0 125984.0 179051.0 174515.0 161327.0 True False 126552.37064031042 39192.72399954896 77709.74385235277 145125.50225856292 98331.36859482434 174591.395879371 114049.88347482677 174351.10097021633 177066.95172505628 190574.30803617023 0.6640578782334673 0.20565586412681786 0.40776610789322015 0.7615166165578766 0.5159738980983808 0.9161329125552132 0.5984536144986583 0.9148720137927784 0.9291228893846997 1.0 17.53999411221998 -6.7171744151903106 0.4573090100043497 0.9939757215952463 0.35475328410918355 0.5637305234616323 0.1636223340651638 0.8748030247094517 0.38198163079409775 0.1525255681304845 0.2321065144240026 1.9178983468504293e-07 6.7171744151903106 -0.6392224374860627 LKATVTPS(ph)PVKGK ddPTM_PC-9_Lapatinib_30min_R1 1 LKATVTPSPVKGK 13 2 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 LKAT(0.004)VT(0.161)PS(0.835)PVKGK 125.45 0.0018573 7307200.0 109910.0 30863.0 33468.0 29675.0 29298.0 29102.0 18044.0 16113.0 30658.0 21633.0 True False 108342.66324497445 30791.53861971707 30716.390230216017 31857.398492898043 27574.749242084225 27857.375300075426 18978.230030029932 16861.668803398483 27204.97319694774 25372.235225839413 4.2701268642912815 1.2135918789038567 1.2106300433055281 1.2556007860298433 1.0868080402313842 1.0979472266481716 0.7479920417379016 0.664571672669436 1.0722339973122212 1.0 14.630963002111875 -4.759155769577239 4.870672774265737 1.020405079521388 4.5007018530688585 0.9685474317559195 0.17500405814949857 0.0332894978803677 1.9770597024978447 0.05128553743240725 0.401164455013865 1.7411822468310932e-05 4.759155769577239 3.4802967735474706 up LKDDEVAQLK ddPTM_PC-9_AZD4547_30min_R2 1 LKDDEVAQLK 10 1 A0A5F9ZHM4;P07195 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain 0 144.17 0.00017123 5626000.0 52183.0 71228.0 57930.0 68705.0 70528.0 59516.0 70011.0 64607.0 57195.0 62750.0 False True 68776.10852617201 94251.05806054326 57161.8103492104 52866.123731668624 60736.40460189629 55794.455111533534 76241.84337072163 54623.4726711653 60218.21093409331 60553.14159961351 1.1357975277472803 1.5565015384956482 0.9439941320827397 0.8730533599929033 1.003026482151736 0.921413053685222 1.2590898070135514 0.9020749580978626 0.994468814388941 1.0 15.885914190874624 -5.279015362241352 24.90392977406934 0.9875006799205012 1.3461495428710182 0.5213115697972617 0.13760763245854357 499.9849968094887 708443.17288178 0.0347074305363342 0.07251774644239492 5.259986599804954e-06 5.279015362241352 0.358648862950517 LKDDEVAQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LKDDEVAQLK 10 1 A0A5F9ZHM4;P07195 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain 0 113.69 0.0016477999999999998 8521100.0 58431.0 71711.0 59848.0 64464.0 66593.0 43629.0 60420.0 54255.0 49055.0 51412.0 False True 68322.21423514494 78829.99415851156 61275.003294803944 60852.29107510787 53544.57969185032 41341.018435535014 54696.580197080955 52830.863737924235 49772.33657205767 60732.588622831965 1.1249679255308362 1.2979850842201053 1.008931196319336 1.0019709756325272 0.8816449439423472 0.6807056865676423 0.9006133517009052 0.8698931650356636 0.8195326051579848 1.0 15.890183242459335 -5.718062274974212 1.4938477199568327 0.8473684345208446 1.2122664578894269 0.6735884795074835 0.0926016453095509 0.22606556728050392 1.0097087705478658 0.029489557978387614 0.0715623528457392 1.9139814529825056e-06 5.718062274974212 0.36489802336858224 LKDDEVAQLK ddPTM_PC-9_Lapatinib_30min_R1 2 LKDDEVAQLK 10 1 A0A5F9ZHM4;P07195 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain 0 ; 131.83 0.00021629 37900000.0 323250.0 295650.0 311760.0 317370.0 314740.0 245820.0 346050.0 315000.0 237440.0 320830.0 False True 318640.3957232106 294965.4405896816 286128.2962284014 340710.44851528376 296227.61200264835 235306.85163440777 363966.77576434606 329636.049964036 210697.00684595417 376285.03802089737 0.8468059144714507 0.7838883048368785 0.760403065009752 0.9054584001194383 0.787242600876937 0.6253420355803245 0.9672634811063968 0.8760275234375099 0.5599399007575021 1.0 18.5214664000313 -10.67945038276458 4.640340389260753 1.0000238641604016 0.7953746791053679 0.22369725819663877 0.11686571574626976 163476974.12186345 3.0286924650172082 43589.77514542975 0.02766134823855716 2.091941893432871e-11 10.67945038276458 -0.2046491850550337 LKDLFDYS(ph)PPLHK ddPTM_PC-9_AZD4547_30min_R2 4 LKDLFDYSPPLHK 13 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 LKDLFDYS(1)PPLHK;LKDLFDYS(1)PPLHK;LKDLFDY(0.003)S(0.997)PPLHK;LKDLFDY(0.233)S(0.767)PPLHK 79.32600000000001 0.006606600000000001 855793900.0 1117016.0 1060685.0 1373049.0 1618733.0 1533050.0 1414429.0 1171636.0 1400772.0 1230884.0 1264810.0 True False 1472203.852623855 1403530.6834243182 1354841.4731257197 1245559.1160255456 1320212.4698692316 1325984.5310328538 1275909.3342403183 1184314.8739383284 1295946.0153405108 1220529.3868782048 1.2062010701678947 1.1499360019623803 1.1100441232234892 1.0205072728411402 1.0816720056581268 1.086401151245015 1.045373710750022 0.9703288480152832 1.0617900963902245 1.0 20.219075600857053 -1.5228787452805195 0.35135307530306914 1.015968113004942 3.3414594608246824 0.757059994358001 0.032991558729091236 30.932228825737393 0.4349756462920545 0.0289011281158293 47.714881279125066 0.029999999999987433 1.5228787452805195 2.3254913478197405 LKDLFDYS(ph)PPLHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LKDLFDYSPPLHK 13 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 LKDLFDYS(1)PPLHK;LKDLFDY(0.127)S(0.873)PPLHK;LKDLFDY(0.006)S(0.994)PPLHK;LKDLFDY(0.001)S(0.999)PPLHK;LKDLFDY(0.001)S(0.999)PPLHK 91.065 0.0025004000000000003 876086900.0 1096808.0 1127911.0 1118296.0 1398737.0 1478572.0 1317898.0 1411946.0 1291842.0 1312142.0 1094028.4 True False 1282475.931454551 1239882.5499758865 1144960.4178011955 1320370.300656536 1188856.4306179094 1248785.1088531658 1278196.2532761954 1257932.5163197424 1331329.5944212216 1292367.088595952 0.9923464801690773 0.9593888307097904 0.8859405565992079 1.0216681562906458 0.9199061482674414 0.9662773989469707 0.9890349766372092 0.973355424646708 1.0301481724264576 1.0 20.301584485854093 -7.694520564072894 1.2536388216585181 1.0106775760070636 0.9553469156727339 0.24668470499312056 0.036429898027831795 0.6667280646700287 1.9270299297120963 0.028972799685733422 0.011785520888974178 2.0205957534518727e-08 7.694520564072894 -0.05533066033432976 LKDLFDYS(ph)PPLHK ddPTM_PC-9_Lapatinib_30min_R1 2 LKDLFDYSPPLHK 13 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 LKDLFDYS(1)PPLHK;LKDLFDYS(1)PPLHK 78.22800000000001 0.007187399999999999 115850000.0 126836.0 104184.0 111669.0 99973.0 104993.0 99630.0 90144.0 91838.0 109380.0 87241.0 True False 125027.29538112656 103942.76834904589 102488.00587480549 107325.34792015176 98817.51816418016 95369.05714887338 94811.21524202048 96105.12875110243 97060.4725775375 102320.49060867455 1.2219184509121868 1.0158548667106744 1.0016371624601723 1.0489135390350925 0.9657647024202461 0.9320621566760565 0.9266102486219173 0.939255941594897 0.9485927207752157 1.0 16.64273556125341 -1.522878745308379 0.7136245975646585 0.9535802436065506 35.65033894817095 0.822236606083319 0.03512389454877533 128.7827752610694 0.6467407116215548 0.014440840478527358 7145.654421387248 0.02999999999806297 1.522878745308379 34.696758704564395 LKDLFDYSPPLHK ddPTM_PC-9_AZD4547_30min_R2 1 LKDLFDYSPPLHK 13 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 0 77.279 0.0073431 683430.0 5595.0 6319.5 8797.4 10421.0 10925.0 8150.4 7325.3 9842.5 6857.9 9015.9 False True 7374.093616770444 8362.154790442019 8680.74072788095 8018.5994528450365 9408.252329226925 7640.7541995605025 7977.2375090135465 8321.567783149574 7220.394593319667 8700.25608522638 0.8475720190917313 0.9611389260876493 0.9977569215027396 0.9216509691549376 1.0813764832971722 0.8782217586140961 0.9168968626750462 0.9564738901513665 0.8299059846732998 1.0 13.086842150847454 -10.63358893425348 10.336036021936625 0.9999999999346418 0.9378381546242113 0.07262935638754198 0.07009688502446597 4.6589419842667655e-11 0.0 0.06649317213904922 0.01612696306539279 2.3249363397133297e-11 10.63358893425348 -0.062161845310430563 LKDLFDYSPPLHK ddPTM_PC-9_Lapatinib_30min_R1 1 LKDLFDYSPPLHK 13 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 0 64.22399999999999 0.019171 561820.0 11075.0 8529.4 11163.0 9271.8 11945.0 10961.0 8359.1 8068.5 10053.0 7287.3 False True 10917.068469093741 8509.650698344776 10245.221230426127 9953.679101818092 11242.41858477357 10492.223581338969 8791.893296609578 8443.391965507399 8920.72527721689 8546.900095283114 1.2773132185221965 0.9956417652572194 1.198706094163928 1.1645952322891144 1.3153796650762382 1.2276057359240042 1.0286645682756572 0.9878893951465703 1.0437381012725402 1.0 13.061185543480951 -7.299446778711056 7.399685829370223 1.0132845334437344 1.1914324883122474 0.5478249762975871 0.08069358467237814 0.21661377264738282 36.15463847522755 0.035052711319143184 0.02379341414542968 5.0182607232086965e-08 7.299446778711056 0.17814795486851298 LKDPANFQYPAESVLAYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LKDPANFQYPAESVLAYK 18 1 B4DLR8;P15559-3;P15559-2;P15559;H3BRK3;H3BNV2 B4DLR8 NQO1 NAD(P)H dehydrogenase [quinone] 1 0 66.20100000000001 0.018403 3059800.0 24436.0 24948.0 23423.0 28776.0 26261.0 26419.0 27644.0 25447.0 21700.0 20590.0 False True 28572.532167000412 27424.672564411918 23981.49315222218 27163.774013050737 21115.34556616586 25033.54113200852 25025.360194771692 24779.04321332519 22017.321447633305 24322.80400964967 1.1747219669107531 1.1275292336168 0.9859674543571506 1.1168027338572462 0.868129577403522 1.0292210191751279 1.028884670733 1.018757672984353 0.9052131258755486 1.0 14.570021936358414 -4.851757864982591 0.9280833887553864 0.9868317919508401 1.2763794385960299 0.4889838195512848 0.06494225283570713 1.655519170580907 1.2087814453285544 0.022069038928679542 0.4752031251237658 1.406831665492843e-05 4.851757864982591 0.2895476466451897 LKDPANFQYPAESVLAYK ddPTM_PC-9_Lapatinib_30min_R1 2 LKDPANFQYPAESVLAYK 18 1 B4DLR8;P15559-3;P15559-2;P15559;H3BRK3;H3BNV2 B4DLR8 NQO1 NAD(P)H dehydrogenase [quinone] 1 0 ; 119.23 0.00011825 10968200.0 136923.0 130414.0 143642.0 124624.0 123163.0 133022.0 149668.0 121364.0 123263.0 137261.0 False True 134970.45291139695 130112.0343956122 131832.30923415476 133789.2646934772 115918.79448777462 127332.9591494273 157417.07670885173 127003.01450106471 109379.82292306646 160986.38096121408 0.8383967147128734 0.8082176493361861 0.8189034901400554 0.8310595212753469 0.7200534218835726 0.7909548521381148 0.9778285328792982 0.7889053331266769 0.679435255765014 1.0 17.296579119604125 LKEDILENEDEQNS(ph)PPK ddPTM_PC-9_AZD4547_30min_R2 4 LKEDILENEDEQNSPPK 17 1 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 LKEDILENEDEQNS(1)PPK;LKEDILENEDEQNS(1)PPK;LKEDILENEDEQNS(1)PPK;LKEDILENEDEQNS(1)PPK 103.58 0.0004016 103577600.0 398439.0 405504.0 351187.0 314764.0 347898.0 368173.0 435049.0 375091.0 377134.0 371367.0 True False 525134.3139539592 536575.237937083 346530.03091849084 242200.02285532228 299598.36785660335 345151.08410811593 473767.51819841244 317129.3046837045 397068.5333056797 358365.5543653175 1.4653593448287658 1.497284634086508 0.9669736019473525 0.6758462689983419 0.8360132948246277 0.9631257242884154 1.3220230360517693 0.8849324406899419 1.1079986021784571 1.0 18.451072448510487 -5.26284620679159 24.22203636362881 0.9625956829980499 1.4813220550044088 0.6199975780398755 0.16016806316814342 50.97755622401929 877738.0015596508 0.04491958133066121 0.10255055011124281 5.459511601524714e-06 5.26284620679159 0.518726372006359 LKEDILENEDEQNS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LKEDILENEDEQNSPPK 17 1 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 LKEDILENEDEQNS(1)PPK;LKEDILENEDEQNS(1)PPK;LKEDILENEDEQNS(1)PPK;LKEDILENEDEQNS(1)PPK;LKEDILENEDEQNS(1)PPK 123.43 2.1115e-05 58615800.0 276261.0 294073.0 193719.0 285789.0 263316.0 199847.0 287942.0 216830.0 216900.0 193610.0 True False 323026.5308965335 323266.62397924945 198337.99564339855 269777.16887043975 211721.12002972214 189366.67150946334 260666.04924044883 211138.44225037508 220071.75216551474 228709.9603840829 1.4123850590243667 1.4134348300195292 0.8672031393399774 1.179560209871887 0.9257188435264007 0.8279773700780299 1.1397232057698783 0.9231711723258612 0.9622307301174745 1.0 17.803159671335557 -5.252050516065203 24.89322322491221 0.9811751720884127 1.4129100247801532 0.7365782580903109 0.10397451441035929 298.50379586163643 791435.3565612674 0.025879035526284778 0.06653429500623592 5.596924956551889e-06 5.252050516065203 0.4317348526917405 LKEDILENEDEQNS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 5 LKEDILENEDEQNSPPK 17 1 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 LKEDILENEDEQNS(1)PPK;LKEDILENEDEQNS(1)PPK;LKEDILENEDEQNS(1)PPK;LKEDILENEDEQNS(1)PPK;LKEDILENEDEQNS(1)PPK 163.04 1.4775999999999999e-05 107107900.0 363285.0 476259.0 331045.0 393278.0 378078.0 393339.0 428575.0 415715.0 327377.0 330985.0 True False 358104.48928168946 475156.2515467655 303827.7579706549 422200.9760569495 355840.19536994706 376516.8078879932 450764.51646641945 435030.6365422203 290504.35482735874 388195.3162402091 0.9224853425591052 1.2240133553098986 0.7826672431633644 1.08759935628821 0.9166524697319088 0.9699158957781207 1.1611796886995245 1.1206488546941413 0.7483458523945695 1.0 18.56642318579651 LKEDILENEDEQNS(ph)PPKK ddPTM_PC-9_AZD4547_30min_R2 3 LKEDILENEDEQNSPPKK 18 2 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 LKEDILENEDEQNS(1)PPKK;LKEDILENEDEQNS(1)PPKK;LKEDILENEDEQNS(1)PPKK 78.501 0.0014232000000000001 44667500.0 221355.0 225149.0 196223.0 206679.0 194621.0 217989.0 227502.0 193039.0 206608.0 221093.0 True False 291741.2855299765 297924.01122133504 193620.95481016935 159032.34970871906 167601.2335529955 204358.11336965032 247749.23727022772 163209.2581449232 217528.87708140825 213352.6013654714 1.3674137726130924 1.3963926819481027 0.9075162598017641 0.7453968158386681 0.7855598313793035 0.9578421451706906 1.1612196696202224 0.7649743059159938 1.0195745244689232 1.0 17.702880175574315 -5.262450460835072 24.30850101949143 0.9086158206457368 1.381903285219663 0.6967444143273299 0.12236504662098435 31.247465678414194 751292.3810397033 0.03306739475191062 0.07585895783562462 5.46448878735587e-06 5.262450460835072 0.47328746457392634 LKEDILENEDEQNS(ph)PPKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LKEDILENEDEQNSPPKK 18 2 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 LKEDILENEDEQNS(1)PPKK;LKEDILENEDEQNS(1)PPKK;LKEDILENEDEQNS(1)PPKK 73.208 0.0023254 31932800.0 253347.0 253447.0 160716.0 260585.0 252290.0 186636.0 282116.0 217511.0 182869.0 199395.0 True False 296233.64326866297 278607.5431871295 164548.07895882416 245985.26727796815 202855.58557891828 176848.47960609972 255391.93013703587 211801.56672195447 185543.1131708414 235543.73509004863 1.257658766238943 1.1828272277359342 0.6985882214015042 1.0443294837959824 0.8612225899422303 0.7508095239234036 1.0842654339305575 0.8992027176650761 0.7877225564921438 1.0 17.84563543465442 -5.115703178075157 6.342251082467633 0.8940771141698896 1.2391806769356994 0.5533305044888877 0.11909173212763338 0.15404045859477558 7.329792787694078 0.02925966845569258 0.08014413125190066 7.661200386888957e-06 5.115703178075157 0.3451035627658099 LKEDILENEDEQNS(ph)PPKK ddPTM_PC-9_Lapatinib_30min_R1 3 LKEDILENEDEQNSPPKK 18 2 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 LKEDILENEDEQNS(1)PPKK;LKEDILENEDEQNS(1)PPKK;LKEDILENEDEQNS(1)PPKK 65.105 0.004884899999999999 51216000.0 227151.0 222979.0 190843.0 213261.0 227966.0 226342.0 209823.0 222885.0 198324.0 159520.0 True False 223911.78508560886 222462.70582528884 175152.62521528406 228944.92535784072 214557.4880784004 216661.8802889726 220686.6082681762 233241.0507816967 175986.66267569535 187092.81945296086 1.1967951829487773 1.1890499404292783 0.9361803714723599 1.2236970185560883 1.146797021423608 1.1580448727132793 1.1795568045499552 1.2466595536037581 0.940638252126732 1.0 17.51339466402355 -8.273453560428027 24.97315820420337 0.9703190900867286 1.155455611471535 0.4630221237874975 0.08143628288324238 766.6025468421051 1593473.3106121428 0.07648656942585644 0.02036475907559651 5.327781918171822e-09 8.273453560428027 0.18513652138480652 LKEELEEAR ddPTM_PC-9_AZD4547_30min_R2 1 LKEELEEAR 9 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73;C9JF13;C9J6B6 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 0 81.525 0.022172 6127000.0 30934.0 28308.0 40161.0 52134.0 43764.0 39849.0 34421.0 43064.0 32443.0 37812.0 False True 40770.368532828776 37458.007406888595 39628.43889926875 40115.31176227072 37688.124021628144 37357.23573055141 37484.40231768737 36409.44831227362 34157.8707463028 36488.213389077064 1.1173572160985443 1.0265782817994 1.086061366631114 1.0994046580060686 1.0328848831198263 1.0238165221247717 1.0273016636355377 0.9978413556190443 0.9361343725458515 1.0 15.15514289200046 -7.141307528131824 0.8559513417632517 0.9724200732579296 1.0790048340793614 0.6625217689118663 0.029722417693854104 0.3825693820696547 0.5628554886376962 0.02236712528617771 0.014571549364443938 7.222581844617585e-08 7.141307528131824 0.10658476082143187 LKETCVSGEDPTQGADLS(ph)PDEK ddPTM_PC-9_Lapatinib_30min_R1 2 LKETCVSGEDPTQGADLSPDEK 22 1 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 LKETCVSGEDPTQGADLS(1)PDEK;LKETCVSGEDPTQGADLS(1)PDEK 146.72 8.5765e-06 15303900.0 120617.0 134566.0 107550.0 125784.0 147548.0 106153.0 116308.0 110434.0 140882.0 109566.0 True False 118896.97946155122 134254.42069471008 98707.65415500599 135034.57496312313 138869.51673052908 101613.08364472918 122329.8591405854 115565.16679913788 125014.38560677115 128504.33711248194 0.9252370941961185 1.0447462218897328 0.7681270249159418 1.0508172564240004 1.0806601539757708 0.7907366080242536 0.9519512095028207 0.8993094660920418 0.9728417609542939 1.0 16.97145752665812 -6.7491146478421715 24.99999258672691 0.9184860822999061 0.9706918245909767 0.06284432771086457 0.09721238564546034 726.0787827424397 1472805.6287333989 0.03206079002897802 0.03183127533244201 1.7819083057723382e-07 6.7491146478421715 0.052205742291070556 LKFGRKDMEPLT(ph)T(ph)LEFS(ph)EK ddPTM_PC-9_AZD4547_30min_R2 1 LKFGRKDMEPLTTLEFSEK 19 3 P23468-2;P23468 P23468-2 PTPRD Receptor-type tyrosine-protein phosphatase delta 3 LKFGRKDMEPLT(1)T(1)LEFS(1)EK 42.611999999999995 0.032416 24835000.0 30918.0 28083.0 24426.0 38419.0 35762.0 28930.0 23785.0 35027.0 27571.0 33171.0 True False 40749.280865649445 37160.2805570034 24102.095280335125 29562.093117632994 30797.063597053868 27121.002526659464 25901.81892234957 29614.381990386606 29028.346772687924 32009.693386466628 1.2730294031144274 1.1609071073674948 0.7529623914025132 0.9235356540507054 0.9621167945980561 0.847274673931302 0.8091867238347429 0.9251691864973397 0.9068611317895602 1.0 14.96622123725323 -5.103044854275358 4.8978015878456915 0.8882604770514184 1.2490217094992326 0.7825540632319863 0.06971100929903007 0.08605000508864112 3.152689781500377 0.017674344205950373 0.05156376916995861 7.887786477329332e-06 5.103044854275358 0.3607612324478142 LKFGT(ph)FGGLGSK ddPTM_PC-9_AZD4547_30min_R2 1 LKFGTFGGLGSK 12 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 LKFGT(0.999)FGGLGS(0.001)K 75.018 0.014563 8590500.0 43067.0 27588.0 59763.0 98941.0 92998.0 78901.0 55378.0 52449.0 44730.0 74852.0 True False 56761.41015075113 36505.28148725599 58970.50357154945 76131.68107321182 80086.83296232909 73967.30799709492 60306.53471859889 44344.21220811906 47094.33648189513 72231.45426317558 0.7858267666042098 0.5053931401443041 0.8164103045286919 1.0539962382015147 1.1087528802968913 1.024031825907793 0.8349068329549589 0.613918308311373 0.6519920851974922 1.0 16.140339596545587 -5.509283506607637 23.380984671506262 0.8967235011302429 0.6494327782937948 0.26307541944967594 0.16721510013513424 390.8418752450962 672163.1571178485 0.050218015912675405 0.0976993752710463 3.0953979696505596e-06 5.509283506607637 -0.24729072283644815 LKFS(ph)DDEEEEEVVK ddPTM_PC-9_AZD4547_30min_R2 2 LKFSDDEEEEEVVK 14 1 Q5JSZ5;Q5JSZ5-5 Q5JSZ5 PRRC2B Protein PRRC2B 1 LKFS(1)DDEEEEEVVK;LKFS(1)DDEEEEEVVK 113.86 8.5831e-05 34442000.0 119670.0 124835.0 102834.0 100812.0 104776.0 123117.0 139722.0 121313.0 114852.0 111255.0 True False 157722.5707093686 165185.47246852276 101470.35396945813 77571.35092987375 90229.66096540769 115418.47452729786 152156.98732262023 102566.86334541251 120922.84224499483 107359.99631338644 1.4691000011677775 1.5386128738896596 0.9451411834372991 0.7225349626823858 0.8404402390442071 1.0750603436161503 1.4172596176183752 0.9553545721631486 1.1263305364878937 1.0 16.71209700154713 -5.259379512944155 24.98899474360225 1.0091790688017104 1.5038564852567031 0.5612439512293479 0.17456529133543483 138.7991181692727 1683791.696731337 0.05028141593802325 0.1202227763378659 5.50326577371003e-06 5.259379512944155 0.49467741645499275 LKFS(ph)DDEEEEEVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LKFSDDEEEEEVVK 14 1 Q5JSZ5;Q5JSZ5-5 Q5JSZ5 PRRC2B Protein PRRC2B 1 LKFS(1)DDEEEEEVVK;LKFS(1)DDEEEEEVVK 81.643 0.013938999999999998 0.0 47176.0 69901.0 40761.0 43362.0 44570.0 36140.0 50839.0 35164.0 29854.0 36851.8 True False 55161.96503152769 76840.3093203848 41732.896826953314 40932.56772150075 35836.82844842206 34244.75477916604 46023.16187751401 34240.982259337725 30290.558271780857 43532.73962131172 1.2671374581838357 1.7651154048381361 0.9586554209540885 0.9402708875565912 0.8232155559278865 0.7866436865002935 1.0572080295856934 0.7865570271294123 0.6958109812356476 1.0 15.409813194844329 -5.370009608237805 5.631561010077833 0.8702401957449125 1.511533722723302 0.7383442250873202 0.15170140058074025 0.09709629213315368 4.201828875868758 0.038304694394936896 0.08161974127704955 4.265700813523705e-06 5.370009608237805 0.6412935269783896 LKFS(ph)DDEEEEEVVK ddPTM_PC-9_Lapatinib_30min_R1 2 LKFSDDEEEEEVVK 14 1 Q5JSZ5;Q5JSZ5-5 Q5JSZ5 PRRC2B Protein PRRC2B 1 LKFS(1)DDEEEEEVVK;LKFS(1)DDEEEEEVVK 63.292 0.021255 27800000.0 52984.0 76774.0 64323.0 75327.0 85219.0 80876.0 90627.0 81580.0 67617.0 74592.0 True False 52228.43844392438 76596.23451998064 59034.611233960335 80866.79886350557 80206.58596700034 77417.1220111642 95319.22261868331 85370.5046224323 60001.26142142386 87485.12781240755 0.5969979098152166 0.8755343500694688 0.6747959648701316 0.924349096647678 0.9168025237270679 0.8849175162339369 1.08954773230799 0.9758287694965756 0.6858452736113417 1.0 16.41675016386686 -5.772764369244678 24.81958873942708 0.9291237615162308 0.7317519102450628 0.401215923943695 0.11676039338259112 200.49097745149146 439391.59933519835 0.03243685090207358 0.0486070167347591 1.6874683296511554e-06 5.772764369244678 -0.19737185127116796 LKFY(ph)Y(ph)NPNFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LKFYYNPNFK 10 1 Q96LI6 Q96LI6 HSFY1 Heat shock transcription factor, Y-linked 2 LKFY(1)Y(1)NPNFK 84.476 0.022524000000000002 0.0 719.4 785.26 1012.5 1164.3 929.2 715.48 469.26 1258.7 2199.5 2168.9 True False 841.1802112023281 863.2154231974545 1036.641839927633 1099.0680457115295 747.1299303180124 677.958969269445 424.80829565180716 1225.6604587028892 2231.6635264548145 2562.1044009970456 0.32831613375121715 0.3369165686072485 0.40460562010050133 0.4289708277632348 0.29160791809547887 0.26461020441072447 0.16580444399006244 0.47838037287860796 0.8710275528141478 1.0 11.323113548683544 -8.242144843040569 2.759066709046039 0.9865328450677943 0.3221882047628537 0.9209055043180105 0.07172373632216313 0.07344674386322332 1.0295671703110232 0.07150272537925231 0.020823748914385803 5.726050276719699e-09 8.242144843040569 -0.6643446403049406 down LKLS(ph)PSPSSR ddPTM_PC-9_AZD4547_30min_R2 1 LKLSPSPSSR 10 1 P20700;Q03252 P20700;Q03252 LMNB1;LMNB2 Lamin-B1;Lamin-B2 1 LKLS(0.988)PS(0.009)PS(0.002)SR 71.888 0.015096 729980000.0 378650.0 307900.0 414280.0 508230.0 449770.0 431130.0 369600.0 439060.0 331260.0 379400.0 True False 499052.82359072956 407422.65368733194 408786.37651425705 391065.4255752268 387327.19909532176 404171.37294568523 402493.68398992624 371213.365595087 348769.72731930664 366117.3214803722 1.3630953640020118 1.1128199344405345 1.1165447590989555 1.0681423757662667 1.0579319151827855 1.103939500353176 1.0993571196316758 1.0139191560074494 0.9526173902646242 1.0 18.481946505447965 -1.5228787453994417 0.8549420555695337 1.0455976369872686 113.31454008307026 0.8054864919355975 0.04632843494593938 312.13491256537156 0.8472760139287706 0.016816563052769327 68181.13754607295 0.02999999999177258 1.5228787453994417 112.26894244608299 LKLS(ph)PSPSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LKLSPSPSSR 10 1 P20700;Q03252 P20700;Q03252 LMNB1;LMNB2 Lamin-B1;Lamin-B2 1 LKLS(0.992)PS(0.007)PS(0.001)SR 55.776 0.041752 53177000.0 90051.0 81419.0 83909.0 87848.0 91177.0 87094.0 102110.0 92522.0 85350.0 60902.0 True False 105294.85571167775 89501.74024057439 85909.70878665458 82926.16136705874 73311.52136957111 82526.63731977557 92437.40158761872 90093.3955351623 86598.08228366384 71943.05050003316 1.4635861974135949 1.2440637367820973 1.194134919072065 1.15266395837664 1.0190215852681603 1.1471106207782715 1.2848690866614854 1.252287676279737 1.2037032302880168 1.0 16.13456771288937 -4.624689152819856 1.6863277582456668 1.1635397606111082 1.666394795690428 0.5420631048466448 0.0853424493960568 1.2772914432096598 2.6280428506809663 0.025014423748220438 1.1820966659782135 2.3730716289050854e-05 4.624689152819856 0.5028550350793197 LKLS(ph)PSPSSR ddPTM_PC-9_Lapatinib_30min_R1 2 LKLSPSPSSR 10 1 P20700;Q03252 P20700;Q03252 LMNB1;LMNB2 Lamin-B1;Lamin-B2 1 LKLS(0.632)PS(0.333)PS(0.033)S(0.002)R;LKLS(0.867)PS(0.128)PS(0.006)SR 66.393 0.021855 1205990000.0 739010.0 608040.0 595620.0 574890.0 614060.0 491680.0 502890.0 548420.0 544470.0 419900.0 True False 728471.581882165 606632.1207378666 546650.4227596885 617169.3283768201 577942.1980884105 470651.9925620608 528927.1835403321 573901.5953056401 483146.0550767215 492479.15551841917 1.4791927205839264 1.231792480839685 1.1099970762909643 1.2531887318705763 1.1735363651686472 0.9556790115646997 1.0740092806233497 1.1653317483082302 0.9810487401606409 1.0 18.909703137347734 -1.5228787452803376 0.45730417368143356 1.0517540462844226 10.471453699529889 0.704715799895658 0.08098196444045914 54.32010356033896 0.643524108240111 0.051553962273785774 479.96811380744333 0.029999999999999995 1.5228787452803376 9.419699653245466 LKMPPASMRT(ph)S(ph)T(ph)SEKELCK ddPTM_PC-9_Lapatinib_30min_R1 1 LKMPPASMRTSTSEKELCK 19 3 Q12955;A0A087WTF3 Q12955 ANK3 Ankyrin-3 3 LKMPPAS(0.586)MRT(0.707)S(0.707)T(0.529)S(0.472)EKELCK 45.363 0.029272000000000003 10914000.0 1275.8 2701.0 1377.2 1501.7 832.64 1637.7 1636.7 1232.9 1394.0 898.97 True False 1257.6068580469343 2694.746000448945 1263.971932145736 1612.1400275243477 783.6657522332242 1567.659388665162 1721.440317565394 1290.1850349227323 1236.9930405292298 1054.3557666977708 1.1927727791405205 2.5558223187689824 1.198809711170339 1.5290285105316495 0.7432650126130155 1.4868410058352994 1.6326939842676857 1.2236714358414102 1.173221676781336 1.0 10.04214603612186 -5.365415828150077 24.23764343216698 1.270641198403429 1.8755015423905093 0.2877075855796515 0.39265577187184475 28.08841630253894 6533.935526737628 0.09682949216113412 0.2015667080198217 4.311061038098968e-06 5.365415828150077 0.6048603439870803 LKNDMAVPT(ph)PPPPPVPPTK ddPTM_PC-9_AZD4547_30min_R2 4 LKNDMAVPTPPPPPVPPTK 19 1 G3V1P5;Q96RN5-3;Q96RN5-2;Q96RN5 G3V1P5 MED15 Mediator of RNA polymerase II transcription subunit 15 1 LKNDMAVPT(1)PPPPPVPPTK;LKNDMAVPT(1)PPPPPVPPTK;LKNDMAVPT(1)PPPPPVPPTK;LKNDMAVPT(1)PPPPPVPPTK 97.095 0.00044931 38663400.0 204551.0 186414.0 232338.0 318697.0 287664.0 263964.0 213811.0 284474.0 227851.0 252502.0 True False 269593.9630748897 246668.67997554486 229257.04631304738 245226.33046956675 247726.81904208058 247458.28935178436 232839.76479320962 240515.07986219856 239894.73869296437 243661.98183562726 1.106426045802894 1.012339627697627 0.9408814809185236 1.0064201588699002 1.0166822791796688 1.015580220958385 0.9555851226322282 0.9870849693098549 0.9845390605695548 1.0 17.894521641805206 -4.7928694946529955 3.8620553785849854 0.988673029318901 1.1163953339903716 0.6970532505948798 0.02325380610619342 0.13297249198015568 3.5766821873545602 0.00606082638098056 0.04697570015081013 1.6111297063825767e-05 4.7928694946529955 0.1277223046714706 LKNDMAVPT(ph)PPPPPVPPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LKNDMAVPTPPPPPVPPTK 19 1 G3V1P5;Q96RN5-3;Q96RN5-2;Q96RN5 G3V1P5 MED15 Mediator of RNA polymerase II transcription subunit 15 1 LKNDMAVPT(1)PPPPPVPPTK;LKNDMAVPT(1)PPPPPVPPTK 75.564 0.0025862 25141800.0 115566.0 124633.0 123939.0 145258.0 163999.0 143844.0 144000.0 126055.0 134853.0 112774.0 True False 135129.04126745628 137005.74056919775 126894.1758012747 137119.66519279013 131864.57322667234 136300.56741711008 130359.27753028258 122746.18981631286 136824.97000818842 133219.033481507 1.0143373490711778 1.0284246701745994 0.9525228676793372 1.0292798379431614 0.9898328322955241 1.0231313338272405 0.9785334281709722 0.9213862809877843 1.0270677277296263 1.0 17.023440694591244 -7.3823655303377045 7.477570501236034 0.9747521489824637 1.0050581555194473 0.10392478821724205 0.03280667428315322 0.49941593049790917 28.553070750198657 0.013231012360040725 0.00887832764942934 4.1460493739718926e-08 7.3823655303377045 0.030306006536983676 LKNDMAVPT(ph)PPPPPVPPTK ddPTM_PC-9_Lapatinib_30min_R1 4 LKNDMAVPTPPPPPVPPTK 19 1 G3V1P5;Q96RN5-3;Q96RN5-2;Q96RN5 G3V1P5 MED15 Mediator of RNA polymerase II transcription subunit 15 1 LKNDMAVPT(1)PPPPPVPPTK;LKNDMAVPT(1)PPPPPVPPTK;LKNDMAVPT(1)PPPPPVPPTK;LKNDMAVPT(1)PPPPPVPPTK 107.69 0.00014248 29037800.0 237452.0 185116.0 210912.0 185736.0 213360.0 200706.0 185001.0 183785.0 201026.0 168167.0 True False 234065.8909366364 184687.37527549328 193571.62950386445 199395.64503713237 200810.58428189944 192122.27224853772 194579.44656315513 192324.32204012887 178384.33498237387 197234.44188155732 1.1867394391350625 0.936385012240414 0.981429144206505 1.0109575342671282 1.0181314296135442 0.9740807458157357 0.9865388859416523 0.9751051601607337 0.904427914722403 1.0 17.589551977435647 -4.754344184420433 24.999307362993633 0.978356571625036 1.1867397998374525 0.7921282596176444 0.0323196784679577 113.04660271601549 398275.6049642979 0.008242093974430247 0.08116449326996496 1.760580209058985e-05 4.754344184420433 0.2083832282124165 LKNGFPHPEPDCNPSEAASEESNS(ph)EIEQEIPVEQK ddPTM_PC-9_AZD4547_30min_R2 1 LKNGFPHPEPDCNPSEAASEESNSEIEQEIPVEQK 35 1 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 LKNGFPHPEPDCNPS(0.001)EAAS(0.008)EES(0.107)NS(0.884)EIEQEIPVEQK 57.95 0.00021887 7032300.0 39589.0 33887.0 47013.0 59215.0 51797.0 52043.0 38612.0 44501.0 35655.0 54538.0 True False 52177.47849764526 44840.31005359736 46389.57690225148 45563.896612630175 44605.88063130137 48788.74298288761 42048.3931986446 37624.39298124856 37539.65050887482 52628.641220075246 0.9914274297802336 0.8520134476983795 0.881451160942307 0.865762359740532 0.8475590400438918 0.9270378609789587 0.7989640664065861 0.7149033702754366 0.7132931734242701 1.0 15.683560526985785 -7.371138886837923 5.756456423903322 0.7806275781955766 0.8880453974995997 0.17668513632053995 0.08529959973896317 0.3193491788039928 14.317917565918625 0.034597541152665466 0.02305104427280146 4.254623290487727e-08 7.371138886837923 0.10741781930402305 LKPGGVGAPSSS(ph)SPSPSPSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LKPGGVGAPSSSSPSPSPSAR 21 1 Q92797 Q92797 SYMPK Symplekin 1 LKPGGVGAPS(0.005)S(0.013)S(0.869)S(0.102)PS(0.005)PS(0.005)PS(0.001)AR;LKPGGVGAPS(0.001)S(0.005)S(0.852)S(0.095)PS(0.044)PS(0.002)PS(0.001)AR 135.69 1.3157000000000001e-05 12535900.0 35390.0 50628.0 41353.0 34585.0 42612.0 30845.0 39426.0 25886.0 30650.0 26115.4 True False 41380.82801563858 55654.013251204364 42339.01235212586 32647.314576082827 34262.48449280149 29227.433900480828 35691.28386047855 25206.519928484136 31098.198265896826 30849.915290607358 1.3413595345669391 1.804024832060039 1.3724190797054312 1.0582626975971863 1.1106184302306055 0.9474072659570474 1.1569329615418817 0.8170693400950302 1.0080480926106485 1.0 14.91297890749826 -5.661568985276473 2.9708480923809466 1.0084907157205931 1.5789546638427197 0.7425212859548561 0.1358758749979761 0.11367276921973896 2.0028659074108073 0.0368174306452199 0.06984170736161908 2.1798721090555175e-06 5.661568985276473 0.5704639481221265 LKPGGVGAPSSS(ph)SPSPSPSAR ddPTM_PC-9_Lapatinib_30min_R1 1 LKPGGVGAPSSSSPSPSPSAR 21 1 Q92797 Q92797 SYMPK Symplekin 1 LKPGGVGAPS(0.005)S(0.035)S(0.42)S(0.008)PS(0.42)PS(0.056)PS(0.056)AR 113.8 1.8376e-06 27123000.0 15444.0 36028.0 29382.0 25728.0 36218.0 39567.0 40647.0 51293.0 31576.0 26938.0 True False 15223.765727917258 35944.57937955371 26966.3253777999 27620.12294609202 34087.72844732765 37874.811645181944 42751.50277270153 53676.26003430266 28019.578369979183 31594.197407371248 0.48185321917262564 1.1376956001157186 0.8535214561743665 0.8742150525288533 1.078923702596561 1.1987901182242207 1.3531441302803018 1.698927791777975 0.8868583686016323 1.0 14.9473719968029 -6.532507313488824 1.8038094287997009 1.288631777053098 0.8513778173475406 0.3376854621417017 0.25276776025065323 0.37826194595412566 2.491391454318756 0.09389341522121561 0.10156562450787351 2.9342200914779637e-07 6.532507313488824 -0.43725395970555736 LKPGGVGAPSSSSPS(ph)PSPSAR ddPTM_PC-9_Lapatinib_30min_R1 2 LKPGGVGAPSSSSPSPSPSAR 21 1 Q92797 Q92797 SYMPK Symplekin 1 LKPGGVGAPSS(0.002)S(0.036)S(0.004)PS(0.941)PS(0.014)PS(0.002)AR;LKPGGVGAPSS(0.004)S(0.069)S(0.026)PS(0.672)PS(0.14)PS(0.089)AR 163.32 2.9863e-24 23670000.0 26131.0 53467.0 50096.0 47051.0 52517.0 55985.0 64111.0 63791.0 58634.0 45424.0 True False 25758.367148161502 53343.200446502706 45977.300256152215 50511.28749753481 49428.05331239463 53590.65205740921 67430.3538824677 66754.96274049483 52030.021476607544 53275.47787632456 0.4834938732592473 1.0012711771508715 0.8630105648772485 0.9481151462365737 0.9277824485617666 1.0059159334397019 1.2656921452493157 1.2530148090921303 0.9766223326497744 1.0 15.701184008462384 -4.265053161199051 0.5088115685898492 1.115334028879622 8.503140882514084e-12 0.5805635122997517 0.1328966058752411 5.58670858800406 0.7510343513896268 0.0814247386120152 4.15061231115851 5.4318383727544833e-05 4.265053161199051 -1.1153340288711189 LKPGGVGAPSSSSPSPS(ph)PSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LKPGGVGAPSSSSPSPSPSAR 21 1 Q92797 Q92797 SYMPK Symplekin 1 LKPGGVGAPSSS(0.032)S(0.036)PS(0.132)PS(0.608)PS(0.191)AR;LKPGGVGAPSSSSPS(0.163)PS(0.541)PS(0.295)AR 178.42 1.9282e-16 16221000.0 45043.0 65507.0 53788.0 48238.0 63546.0 43479.0 56849.0 36764.0 48407.0 43559.0 True False 52667.89026019803 72010.10203931908 55070.509912125926 45535.38124970607 51094.61746877786 41198.88469959493 51463.85116888207 35798.98395467788 49114.860797953246 51455.901887145694 1.0235539234296291 1.3994527235622718 1.0702467140291871 0.884939911257903 0.992978756466844 0.8006639314174941 1.0001544872686094 0.6957216304009803 0.9545039343722539 1.0 15.651048940342033 -5.578880439299152 3.976346649819642 0.8957876519462207 1.2182122603552599 0.49583988958376723 0.12492899375033008 0.14999836940738617 4.865189103946542 0.03224131420304624 0.0606639100626257 2.6370572643077763e-06 5.578880439299152 0.3224246084090392 LKPNLGNGADLPNYR ddPTM_PC-9_Lapatinib_30min_R1 2 LKPNLGNGADLPNYR 15 1 Q9Y266;A0A0A0MSS4;A0A0A0MSU9 Q9Y266 NUDC Nuclear migration protein nudC 0 ; 81.904 0.038209 4891900.0 64228.0 50389.0 43033.0 43853.0 50103.0 47421.0 40786.0 41606.0 45630.0 48660.0 False True 63312.09694202735 50272.32736639094 39494.992852183736 47078.095909319556 47156.04004628799 45392.914373750165 42897.69951256931 43539.166650170504 40490.668894798255 57070.8161646256 1.1093602859892215 0.8808762646985135 0.692034835076777 0.8249066523513314 0.82627239656539 0.7953787491458062 0.7516573687824485 0.7628972139556949 0.7094811607039138 1.0 15.800465574563784 -4.827298703621728 3.2567773147606967 0.787171474787916 1.1381503834119062 0.573595939836608 0.08121579674189429 0.1897107430690138 3.248974655301186 0.019235858548886767 0.15930086429644771 1.4883370614954294e-05 4.827298703621728 0.35097890862399017 LKQLMEQDASS(ph)SPSAQVIGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LKQLMEQDASSSPSAQVIGLK 21 1 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 LKQLMEQDAS(0.003)S(0.529)S(0.382)PS(0.086)AQVIGLK 58.123000000000005 0.020342 4919900.0 19616.0 5514.0 10498.0 24795.0 24845.0 36409.0 23704.0 40745.0 33101.0 24953.0 True False 22936.60136633982 6061.393479243521 10748.3121338867 23405.8165364746 19976.800601324798 34499.647945618635 21458.58551790146 39675.48692289604 33585.03950406036 29476.781372160673 0.7781243507136189 0.2056328132544417 0.364636559133893 0.7940424784159171 0.6777130904865982 1.1704007812128974 0.7279826534306765 1.3459911522215084 1.139372683877207 1.0 14.847291381868137 -6.412863205868997 1.0688612371830628 1.1087398803367108 0.4295098171020374 0.5871978508536865 0.21786116709785633 0.33690869822661995 0.8148477194399619 0.09970826040510807 0.12893666873092874 3.8648869414174026e-07 6.412863205868997 -0.6792300632346734 LKS(ph)EDELRPEVDEHTQK ddPTM_PC-9_AZD4547_30min_R2 1 LKSEDELRPEVDEHTQK 17 2 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;H0YCR2;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 LKS(1)EDELRPEVDEHTQK 53.981 0.018448 22952000.0 85156.0 75563.0 78148.0 90215.0 75136.0 74510.0 89237.0 95836.0 73022.0 80412.0 True False 112233.83664516581 99987.26203499806 77111.70645900385 69417.32555785579 64704.66334176616 69850.87792123732 97178.9201250244 81026.74829219446 76881.79384263232 77596.8003555079 1.4463719654801377 1.2885487749096456 0.9937485322296589 0.8945900506183496 0.8338573632588364 0.9001772959866537 1.252357309577218 1.04420218257676 0.9907856186131413 1.0 16.243709544765835 -5.124605026291733 2.8584857056322486 0.9861762469773008 1.4308998929874537 0.6769670650136568 0.10714655374397267 0.17957069563494774 2.6959519769306404 0.03208416616598947 0.12477348952848417 7.505765187693361e-06 5.124605026291733 0.4447236460101529 LKS(ph)EDELRPEVDEHTQK ddPTM_PC-9_Lapatinib_30min_R1 1 LKSEDELRPEVDEHTQK 17 2 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;H0YCR2;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 LKS(1)EDELRPEVDEHTQK 53.395 0.019684 26870000.0 48129.0 69430.0 51616.0 50532.0 96284.0 109570.0 125790.0 145240.0 106500.0 107510.0 True False 47442.67163422236 69269.2391007666 47372.33172352188 54248.2918498104 90620.76442162729 104883.9465201452 132302.79070480287 151988.38062468782 94504.84850528186 126092.96025192949 0.37625154917002107 0.549350566140798 0.37569370747481506 0.43022458780747264 0.7186821868609481 0.8317985897911399 1.0492480344696988 1.2053676931766861 0.7494855249370334 1.0 16.94412820693772 -6.632198704774049 1.6555338454236077 1.0121294605114306 0.43211497967769025 0.819889347721794 0.11889224090501954 0.14389418949604937 0.8121877236722009 0.04772735984991554 0.04806626159020358 2.3323906685651401e-07 6.632198704774049 -0.5800144808337404 down LKS(ph)EDGVEGDLGETQSR ddPTM_PC-9_AZD4547_30min_R2 11 LKSEDGVEGDLGETQSR 17 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 LKS(1)EDGVEGDLGETQSR;LKS(1)EDGVEGDLGETQSR;LKS(1)EDGVEGDLGETQSR;LKS(1)EDGVEGDLGETQSR;LKS(0.934)EDGVEGDLGET(0.066)QSR;LKS(1)EDGVEGDLGETQSR;LKS(1)EDGVEGDLGETQSR;LKS(1)EDGVEGDLGETQSR;LKS(1)EDGVEGDLGETQSR;LKS(1)EDGVEGDLGETQSR;LKS(0.827)EDGVEGDLGET(0.173)QSR 163.44 0.00014602 828136700.0 308223.0 346167.10000000003 364411.0 448256.9 397995.2 410520.3 392034.1 428473.80000000005 405476.6 387268.7 True False 406231.5025633312 458058.84540840593 359578.6720380821 344918.1972050677 342740.4363772204 384850.400744728 426924.3754293162 362263.01955841295 426909.2652791149 373710.540688419 1.0870217945017144 1.225704912054681 0.9621849878135512 0.9229554953673172 0.9171280953056662 1.0298087927511705 1.1423931865632448 0.9693679468903436 1.142352753798963 1.0 18.51156173064797 -5.2668787830735635 24.996924421195004 1.008579544890127 1.1563633553676644 0.3414784182553354 0.08082512907074856 463.372470591347 2129450.831011832 0.022003370858493625 0.04808284241298753 5.409052751871456e-06 5.2668787830735635 0.14778381047753752 LKS(ph)EDGVEGDLGETQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LKSEDGVEGDLGETQSR 17 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 LKS(1)EDGVEGDLGETQSR;LKS(0.894)EDGVEGDLGET(0.104)QS(0.003)R;LKS(0.999)EDGVEGDLGET(0.001)QSR;LKS(1)EDGVEGDLGETQSR;LKS(1)EDGVEGDLGETQSR 162.81 0.00015046 466139100.0 45682.3 55892.9 45845.09999999999 77709.5 114716.0 160960.0 204018.0 210850.0 166860.0 167196.0 True False 53415.41112344749 61441.57772869246 46938.221052509936 73355.68865259811 92238.2232956964 152518.97424611414 184691.93807759095 205315.4109140421 169300.01183189405 197507.31127719264 0.2704477661005742 0.3110850799971752 0.237653081037766 0.37140745918841805 0.4670116903482332 0.7722193839804776 0.9351144364391863 1.0395332182204189 0.8571835175979339 1.0 17.591546534046124 -6.75885334915842 1.4930898977927527 0.9725655986960984 0.28258103205499824 0.9724800997937835 0.05107079133718783 0.055550648312807836 0.2577983943239634 0.022256475789028694 0.020214513097891202 1.742395139158061e-07 6.75885334915842 -0.6899845666411002 down LKS(ph)EDGVEGDLGETQSR ddPTM_PC-9_Lapatinib_30min_R1 6 LKSEDGVEGDLGETQSR 17 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 LKS(1)EDGVEGDLGETQSR;LKS(1)EDGVEGDLGETQSR;LKS(0.989)EDGVEGDLGET(0.011)QSR;LKS(0.953)EDGVEGDLGET(0.042)QS(0.004)R;LKS(1)EDGVEGDLGETQSR;LKS(1)EDGVEGDLGETQSR 224.15 3.3152e-28 582997800.0 40743.5 48021.0 43865.7 53872.9 144348.0 240060.0 257000.0 260682.0 273546.0 244019.0 True False 40162.49021855721 47909.81032490146 40259.23147249873 57834.89278072613 135857.73443908704 229793.19340719236 270306.2024893421 272794.23738642834 242736.368912919 286197.3590151207 0.14033144944721623 0.16740130129003122 0.1406694723216216 0.20208045587754891 0.4746994692984195 0.8029186369782387 0.9444748317019268 0.95316825537868 0.8481432873742711 1.0 18.126650833596543 -6.60791686688329 1.6832995483671611 0.9372047370554789 0.14739599799363637 0.9890376376366035 0.037443977547933084 0.03354477310596151 0.19506515403101402 0.015093218675877814 0.01548097640565167 2.4665114343191567e-07 6.60791686688329 -0.7898087390618426 down LKS(ph)PQAVLQLGVNNEDSK ddPTM_PC-9_AZD4547_30min_R2 2 LKSPQAVLQLGVNNEDSK 18 1 D6RJ90;Q9Y6G5 D6RJ90 COMMD10 COMM domain-containing protein 10 1 LKS(1)PQAVLQLGVNNEDSK;LKS(1)PQAVLQLGVNNEDSK 123.84 2.136e-05 10534000.0 62445.0 50344.0 75022.0 96573.0 81449.0 87387.0 75040.0 87778.0 81413.0 88251.0 True False 82301.21106331197 66616.71346942206 74027.15926149592 74309.58688797649 70141.21226207828 81922.67707560271 81718.41462825761 74213.92703777531 85716.3249720663 85161.35935151367 0.9664149526266238 0.782241077135155 0.8692576049184465 0.8725739872382121 0.8236272036542072 0.9619700495556569 0.9595715151863077 0.871450709604675 1.0065166364743185 1.0 16.37791135792157 -6.7712602514301325 24.994968999370133 0.9518468273221257 0.8592453960561299 0.42858487640150345 0.055583037171229345 201.87563522876198 513787.94018780673 0.01853367937596046 0.016541743978294447 1.69332277087771e-07 6.7712602514301325 -0.09260143126599574 LKS(ph)PQAVLQLGVNNEDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LKSPQAVLQLGVNNEDSK 18 1 D6RJ90;Q9Y6G5 D6RJ90 COMMD10 COMM domain-containing protein 10 1 LKS(1)PQAVLQLGVNNEDSK 87.24 0.00078437 3391300.0 43371.0 39147.0 41679.0 57257.0 48589.0 47097.0 56714.0 50660.0 49638.0 40403.0 True False 50712.8536837033 43033.25544649001 42672.78542848771 54049.075919698604 39068.33424905496 44627.15041046997 51341.63934619745 49330.22867870688 50363.86184413006 47727.744070027955 1.0625445361359522 0.9016402573595347 0.8940876268083524 1.1324456450402465 0.8185665384002315 0.9350358220365774 1.075718962766542 1.0335755364076646 1.0552323983768077 1.0 15.542540526207752 -7.256278891034743 24.779939004750236 1.0439296862644962 0.9536227866855861 0.18873696587952182 0.08476389816488525 622.0149900141108 2986836.3079229766 0.032669373154066775 0.024506638002866007 5.542696631102704e-08 7.256278891034743 -0.09030689957891014 LKS(ph)PQAVLQLGVNNEDSK ddPTM_PC-9_Lapatinib_30min_R1 2 LKSPQAVLQLGVNNEDSK 18 1 D6RJ90;Q9Y6G5 D6RJ90 COMMD10 COMM domain-containing protein 10 1 LKS(1)PQAVLQLGVNNEDSK;LKS(1)PQAVLQLGVNNEDSK 117.22 5.2984e-05 8462300.0 61970.0 50360.0 54291.0 50868.0 58321.0 59655.0 59558.0 46886.0 58306.0 47911.0 True False 61086.296436093835 50243.39451410915 49827.40354932048 54609.00241067357 54890.67344349767 57103.694712597084 62641.621820467895 49064.49472575818 51738.964290600656 56192.35251260537 1.0870927039829954 0.8941322487404009 0.8867292669076797 0.9718226763761739 0.9768352985610328 1.0162182603012977 1.1147712992869587 0.8731525293366525 0.9207474322950671 1.0 15.77808618005131 -4.73939831647037 24.358018126616535 0.9625861437597414 1.0870933753578251 0.22817238073127 0.06921989049573976 2166.48937392212 2394059.060028361 0.01843941079865783 0.8742996945273348 1.822223669450899e-05 4.73939831647037 0.12450723159808375 LKS(ph)PSMAVPSPGWVASPK ddPTM_PC-9_AZD4547_30min_R2 1 LKSPSMAVPSPGWVASPK 18 1 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 LKS(0.944)PS(0.055)MAVPS(0.001)PGWVASPK 92.236 0.0026235 0.0 20326.0 16178.0 26943.0 33145.0 32934.0 27121.0 25974.0 27423.0 21310.0 28761.0 True False 26789.24519293584 21407.222121967072 26585.718215756544 25503.932335145277 28361.682582220572 25425.119582631574 28285.63568169466 23185.405467849694 22436.403094772744 27754.08614416708 0.9652360756459634 0.771317852469306 0.9579028499680547 0.9189253143723234 1.0218921435531103 0.9160856333212408 1.0191521181697887 0.835387097503927 0.8083999948053803 1.0 14.760412569965332 LKS(ph)PSMAVPSPGWVASPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LKSPSMAVPSPGWVASPK 18 1 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 LKS(0.877)PS(0.122)MAVPSPGWVASPK;LKS(0.925)PS(0.075)MAVPSPGWVASPK;LKS(0.615)PS(0.384)MAVPS(0.002)PGWVASPK 72.99 0.015661 12414000.0 88743.0 94615.0 107925.0 111176.0 119724.0 110553.0 105019.0 103859.0 101624.0 82224.0 True False 103765.43714585513 104007.7519112487 110498.34130784181 104947.16915745512 96264.94164592536 104755.40606256617 95070.84004828287 101132.81129770668 103110.05874628069 97130.56031517393 1.068308849543872 1.0708035820421433 1.1376269317225336 1.080475277985811 0.9910880914674045 1.0785009962122196 0.9787943129308883 1.0412048583838707 1.0615614530761914 1.0 16.56763766364395 -6.103718163307727 6.69482898213916 1.0278207080231787 1.0931003584757897 0.4625774755344034 0.03393856968285792 0.22404679048992057 12.460326048213537 0.009818008936992915 0.012759082463379257 7.875567111589935e-07 6.103718163307727 0.06527965045261097 LKS(ph)PSMAVPSPGWVASPK ddPTM_PC-9_Lapatinib_30min_R1 2 LKSPSMAVPSPGWVASPK 18 1 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 LKS(0.981)PS(0.019)MAVPSPGWVASPK;LKS(0.935)PS(0.064)MAVPS(0.001)PGWVASPK 78.234 0.0021573 9987200.0 148545.0 120518.0 137180.0 122150.0 123027.0 121523.0 107410.0 115778.0 133163.0 97646.0 True False 146426.721060183 120238.94797560388 125901.58993011339 131133.3184804547 115790.79374038828 116325.7445739492 112971.1642388338 121157.46854836881 118164.7806714446 114523.98099488356 1.2785682071838274 1.049901923868466 1.099346956300254 1.1450293409405072 1.01106155003083 1.0157326313966166 0.9864411213916923 1.0579222578176146 1.031790718807825 1.0 16.805290200618046 -1.5228787452803376 0.6185506350539095 1.0260675455417618 16.61121409758245 0.6830846581887169 0.04718174800453044 118.4197593533633 0.8587843046388894 0.021448408143129736 2507.5738746387265 0.029999999999999995 1.5228787452803376 15.585146552040689 LKS(ph)PSQDNTDSYFR ddPTM_PC-9_Lapatinib_30min_R1 1 LKSPSQDNTDSYFR 14 1 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 LKS(0.99)PS(0.01)QDNTDSYFR 77.64399999999999 0.007023100000000001 10895000.0 17383.0 13295.0 19804.0 20241.0 23664.0 16757.0 18902.0 21681.0 24812.0 19348.0 True False 17135.115232348213 13264.216244342362 18175.791565650714 21729.590661996597 22272.130045214042 16040.342172474875 19880.653071803692 22688.378410381825 22017.411278056843 22692.27602041053 0.7551078268630288 0.5845255994776322 0.8009682038638403 0.9575765182149183 0.9814850667769691 0.7068635229911454 0.8760977988246782 0.999828240674263 0.9702601562863645 1.0 14.469913697183856 -3.3647819232425915 0.2725372099562664 0.99193000447204 1.6253730896634926e-12 0.47221970947763225 0.10002438772875918 18.21277478281089 0.6074626318862508 0.13062730960205737 6.943190749133666 0.00043173581435423036 3.3647819232425915 -0.9919300044704147 LKS(ph)PSQKQDGGTAPVASASPK ddPTM_PC-9_Lapatinib_30min_R1 1 LKSPSQKQDGGTAPVASASPK 21 2 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 LKS(0.873)PS(0.126)QKQDGGT(0.001)APVASASPK 57.496 0.040106 7896000.0 35355.0 12998.0 17610.0 18741.0 14493.0 13625.0 10941.0 12453.0 19379.0 11837.0 True False 34850.831216687046 12967.903929594746 16162.173776565789 20119.275658143302 13640.550234334305 13042.290511426289 11507.471445275856 13031.61184191158 17196.332950083186 13883.009678188935 2.5103224750638797 0.9340844838542556 1.1641693084718914 1.449201298890681 0.9825355272757932 0.9394425858476877 0.8288888153232944 0.9386733960421454 1.2386603012385482 1.0 13.76103274120558 -4.758570460645907 24.999994450627288 1.0540586282164979 2.5103244352357073 0.8636119412643835 0.1737595780907531 29.153128774581962 253996.0885293899 0.046785660753161706 0.3170754885276383 1.7435304612886254e-05 4.758570460645907 1.4562658070192094 LKSEDGVEGDLGET(ph)QSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LKSEDGVEGDLGETQSR 17 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 LKS(0.235)EDGVEGDLGET(0.765)QSR 181.98 8.9265e-06 37128000.0 3000.1 3681.7 9245.7 12686.0 36211.0 40153.0 58234.0 68321.0 54386.0 49200.0 True False 3507.9576753240276 4047.19484449236 9466.152552512507 11975.244548566918 29115.714492838513 38047.30599468333 52717.6539423504 66527.64614208319 55181.29236179652 58119.57053301432 0.06035759801995375 0.06963566329509242 0.1628737526051632 0.20604495936122727 0.5009623131385594 0.6546384573346234 0.9070551185921891 1.144668577760614 0.9494442552780267 1.0 15.826736421952763 -6.715109039081602 0.9574672334888847 1.0571433996175705 0.0654421558790211 0.9754269733190661 0.06256143971437764 0.07387892141192812 0.14656744335159372 0.036064308079540454 0.03468403215135908 1.9270410268587548e-07 6.715109039081602 -0.9917012437385494 down LKSPVLSNTT(ph)TEPASTMSPPPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LKSPVLSNTTTEPASTMSPPPAK 23 1 A0A075B784;Q9P275 A0A075B784 USP36 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 36 1 LKS(0.189)PVLS(0.242)NT(0.242)T(0.312)T(0.014)EPASTMSPPPAK 77.873 0.00018611 3874400.0 18986.0 15657.0 17443.0 19914.0 20453.0 17295.0 21109.0 17478.0 13760.0 15699.0 True False 22199.954809407 17211.323486491805 17858.90727294587 18798.283142059103 16445.381473089004 16388.019753892564 19109.4027040745 17019.221019471766 13961.21396863752 18545.10442678439 1.1970789863735667 0.9280790817027578 0.9629984745274631 1.0136520512070588 0.8867775071321362 0.8836844148595688 1.0304284227418585 0.9177204197831954 0.7528247696720202 1.0 14.17875077117467 LKSPVLSNTTTEPASTMS(ph)PPPAK ddPTM_PC-9_Lapatinib_30min_R1 1 LKSPVLSNTTTEPASTMSPPPAK 23 1 A0A075B784;Q9P275 A0A075B784 USP36 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 36 1 LKSPVLSNT(0.003)T(0.008)T(0.008)EPAS(0.063)T(0.273)MS(0.644)PPPAK 82.139 5.2634e-05 5208500.0 69094.0 63300.0 64512.0 58937.0 66528.0 61981.0 58022.0 56898.0 69009.0 49903.0 True False 68108.7068897122 63153.43273914037 59208.07238352143 63271.42358806848 62614.95383908038 59330.21711476792 61026.095256173576 59541.68879636111 61236.479723014025 58528.6670584322 1.1636811551118318 1.079017102441288 1.0116080778742311 1.0810330521435136 1.0698168433695685 1.0136949993331557 1.0426701704183365 1.0173081293123856 1.0462647246327765 1.0 15.836855802415611 -4.834018083727564 2.843854445181582 1.0382879375960656 1.178606872021915 0.7098340079246662 0.024969349567105344 0.19955495793283207 2.4462229021783943 0.006431613220020256 0.062220556724337864 1.4654868178086573e-05 4.834018083727564 0.1403189344258493 LKT(ph)PSTPVACSTPAQLK ddPTM_PC-9_AZD4547_30min_R2 2 LKTPSTPVACSTPAQLK 17 1 Q6PL18;A0A0B4J211 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 LKT(0.747)PS(0.025)T(0.225)PVACS(0.002)T(0.002)PAQLK;LKT(0.654)PS(0.122)T(0.111)PVACS(0.103)T(0.009)PAQLK 73.498 0.0076285 24599000.0 92513.0 77288.0 109683.0 156848.0 156490.0 144947.0 94215.0 138374.0 99260.0 132074.0 True False 121930.20961005946 102269.83455078444 108228.53175440084 120689.11687744349 134764.06471402507 135883.44117634685 102599.95248136079 116991.47781819021 104506.68095669382 127450.12946019709 0.9566895704734336 0.8024302131660329 0.8491833802977878 0.9469517009406799 1.0573866443667452 1.066169502941019 0.8050203865301129 0.9179392623114351 0.8199809713754073 1.0 16.95957331324604 -4.466371221042404 22.6596367521596 0.9175575549909214 1.703106780997077 0.014527333454772862 0.09455883888962957 836.3227056657187 1115956.2329167873 0.024407815905395303 140950.66850488287 3.416872543108018e-05 4.466371221042404 0.7855492260061556 LKTPS(ph)TPVACSTPAQLK ddPTM_PC-9_Lapatinib_30min_R1 1 LKTPSTPVACSTPAQLK 17 1 Q6PL18;A0A0B4J211 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 LKT(0.139)PS(0.504)T(0.356)PVACS(0.001)TPAQLK 73.208 0.005178100000000001 9261600.0 37719.0 29932.0 35697.0 32706.0 39308.0 34863.0 32289.0 37945.0 41748.0 32852.0 True False 37181.12014318256 29862.694293016608 32762.130454404843 35111.30834401764 36995.980722501416 33371.990759622364 33960.76642870962 39708.063225032936 37045.90061407052 38530.424427461614 0.964980809209115 0.7750419243171561 0.8502924881111468 0.9112619148568973 0.9601757902291219 0.866120507508277 0.8814013064570583 1.030563867776447 0.9614713869506966 1.0 15.23371045747584 -7.7517242705388645 24.967083642314627 0.9970132203435069 0.8842583236792227 0.46936275745768685 0.05368948955141038 168.41129119878423 432806.75476389437 0.026312672799231614 0.01494562977573557 1.7712331405906447e-08 7.7517242705388645 -0.11275489666428418 LKTPST(ph)PVACSTPAQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LKTPSTPVACSTPAQLK 17 1 Q6PL18;A0A0B4J211 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 LKT(0.044)PS(0.125)T(0.799)PVACS(0.023)T(0.009)PAQLK 58.79600000000001 0.029557 7786000.0 29491.0 22869.0 39946.0 37508.0 51131.0 52151.0 44858.0 47985.0 51650.0 40595.0 True False 34483.243826199425 25139.283184044245 40898.46413604859 35406.54836257669 41112.247596954636 49416.10975341141 40608.7254962042 46725.444594310095 52405.28353779999 47954.552150156844 0.7190817613774053 0.5242314244813987 0.8528588486862727 0.7383355025756587 0.857316891798356 1.0304779742010328 0.846816906329327 0.9743693246889653 1.092811447257538 1.0 15.549380151054354 -5.999302193118096 0.5716719569018741 1.018582412453598 0.5756846514118097 0.6906724010890579 0.09027229558411862 0.7037367211411638 0.4208731787954848 0.06156685202251233 0.1764677321569239 1.0016080512541e-06 5.999302193118096 -0.44289776104178835 LKVPEWVDTVK ddPTM_PC-9_AZD4547_30min_R2 1 LKVPEWVDTVK 11 1 M0R2L9;M0QYF7;M0R140;P39019 M0R2L9 RPS19 40S ribosomal protein S19 0 105.65 0.0032821999999999994 2926000.0 25113.0 26606.0 32521.0 41299.0 32821.0 31139.0 26535.0 33443.0 27192.0 29446.0 False True 33098.41161715032 35205.869191312624 32089.750291156062 31778.153613189435 28264.370681698594 29191.87340745418 28896.56359489367 28275.152793687696 28629.313606431744 28415.104502664864 1.1648175221050565 1.238984329197554 1.1293201574587408 1.1183542756356633 0.9946952923945033 1.0273364789039037 1.0169437734140183 0.9950747424151108 1.007538564700573 1.0 14.794370400770088 -5.9268160312063385 1.499923507815568 1.0057722957952357 1.1996741174643855 0.9010820251015984 0.025958113730619483 0.10489379938585455 0.47938922914435206 0.00829601921158572 0.01563916861193759 1.1835428027835142e-06 5.9268160312063385 0.1939018216691497 LKVPEWVDTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LKVPEWVDTVK 11 1 M0R2L9;M0QYF7;M0R140;P39019 M0R2L9 RPS19 40S ribosomal protein S19 0 ; 124.12 0.00068386 6362300.0 58615.0 60826.0 53413.0 68525.0 70208.0 66525.0 64059.0 63443.0 62103.0 51725.0 False True 68537.36180097917 66864.4032949703 54686.568489930505 64685.76641104747 56451.246392344954 63036.311889430624 57990.86777300242 61777.68847341493 63011.13888766684 61102.33304512528 1.1216815853882858 1.0943019679066857 0.8949996794646679 1.058646424569022 0.923880375413073 1.0316514729949358 0.9490777992089929 1.0110528582892389 1.0312394919704928 1.0 15.898939846473532 -5.0881465384456215 8.037586764954058 0.9885088535754032 1.1150037673958155 0.4972909285907966 0.04875918987957313 0.19818887038220157 16.103101870388272 0.01135661500919552 0.030472859419095683 8.163068888671426e-06 5.0881465384456215 0.12649491382041234 LKVPEWVDTVK ddPTM_PC-9_Lapatinib_30min_R1 2 LKVPEWVDTVK 11 1 M0R2L9;M0QYF7;M0R140;P39019 M0R2L9 RPS19 40S ribosomal protein S19 0 ; 117.2 0.0015369000000000001 6206300.0 69622.0 60603.0 63347.0 62740.0 67713.0 65549.0 68208.0 64177.0 61079.0 54344.0 False True 68629.17751288881 60462.67747693721 58138.854186491386 67354.10889450452 63730.25446888012 62745.62207218218 71739.47649569291 67158.89770965707 54199.639829616106 63737.28799117169 1.076750826335672 0.9486233158416146 0.9121639156429789 1.0567457608775854 0.9998896482339734 0.9844413537154756 1.1255495606532493 1.0536830139205062 0.8503599939351569 1.0 15.959850013586356 -4.735403910089481 24.246279809155265 0.9977138483034833 1.0767513835847258 0.10126047711122865 0.07388317534831777 4766.720963065462 4438804.87277479 0.018781635160711737 1.3583506220283623 1.839060810612059e-05 4.735403910089481 0.07903753528124247 LLAEPVPGIK ddPTM_PC-9_Lapatinib_30min_R1 1 LLAEPVPGIK 10 0 F8VSD4;F8VV71;P61088;Q5JXB2;F8VZ29 F8VSD4 UBE2N;UBE2NL Ubiquitin-conjugating enzyme E2 N;Putative ubiquitin-conjugating enzyme E2 N-like 0 96.66799999999999 0.025074000000000003 3678000.0 57378.0 70108.0 71016.0 73429.0 67908.0 59011.0 68038.0 52100.0 57558.0 61900.0 False True 56559.779198163495 69945.66923342271 65177.3386096875 78829.2136119631 63913.7849522649 56487.23709135976 71560.6747275093 54520.75620040098 51075.21192738982 72599.33252343455 0.7790674821962915 0.9634478279926987 0.8977677389616318 1.0858118232218952 0.880363258596544 0.7780682704365922 0.9856932872545352 0.7509815077542492 0.7035217839076289 1.0 16.147668663726982 -6.518262863007071 24.610087366772394 0.8361055918219432 0.9378547018948789 0.11649030635567581 0.11260436302939776 319.1628276266539 1701665.2178892922 0.03633827022265785 0.03727489248255547 3.032055433354247e-07 6.518262863007071 0.10174911007293563 LLAQAEGEPCY(ph)IR ddPTM_PC-9_AZD4547_30min_R2 2 LLAQAEGEPCYIR 13 0 H0YE41;E9PPF2;E9PM19;P29597 H0YE41 TYK2 Tyrosine-protein kinase;Non-receptor tyrosine-protein kinase TYK2 1 LLAQAEGEPCY(1)IR;LLAQAEGEPCY(1)IR 81.771 0.016328 6130000.0 15868.2 27335.0 26484.0 33707.0 25252.0 26605.0 24262.0 35767.0 29525.0 23600.0 True False 20913.95752093596 36170.50418494063 26132.804855661805 25936.37191795871 21746.195681248377 24941.385144202395 26421.270998278127 30240.031993894925 31085.631223517867 22773.771183280936 0.9183352793273724 1.5882527269569975 1.147495715371324 1.138870313099464 0.9548789924267378 1.0951802818899306 1.1601623106530092 1.3278447276266323 1.3649751274544715 1.0 14.475085591398331 -10.975033521365088 12.602179567674677 0.9999999761529157 1.1911962203659385 0.0831498557853555 0.18752456281208052 1.2640676363298872e-07 5.623232874796535e-09 0.1829103247759623 0.04436226465676319 1.0591719689910726e-11 10.975033521365088 0.19119624421302284 LLAQAEGEPCY(ph)IR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLAQAEGEPCYIR 13 0 H0YE41;E9PPF2;E9PM19;P29597 H0YE41 TYK2 Tyrosine-protein kinase;Non-receptor tyrosine-protein kinase TYK2 1 LLAQAEGEPCY(1)IR 74.962 0.027395999999999997 1738500.0 4458.2 7255.7 6304.2 8083.7 9569.5 3856.1 6285.4 4193.4 5841.0 4388.7 True False 5212.885206536306 7975.997944749225 6454.516036811634 7630.796496709007 7694.425170230542 3653.879327723914 5690.001409644699 4083.3276932745675 5926.4135749136485 5184.336569069913 1.0055067098916217 1.538479965273579 1.2450032807128484 1.4718945028057848 1.484167755646109 0.7047920749442067 1.0975370394722472 0.7876278167655943 1.1431382773778644 1.0 12.339943666226862 -6.751676920367397 24.99999348237663 0.9427781404888012 1.3605852743852473 0.5381060145209593 0.18623292728540577 146.7970239442481 375921.56581956154 0.057994397980232294 0.05730495907124402 1.7714262647691892e-07 6.751676920367397 0.4178071338964462 LLAQAEGEPCY(ph)IR ddPTM_PC-9_Lapatinib_30min_R1 1 LLAQAEGEPCYIR 13 0 H0YE41;E9PPF2;E9PM19;P29597 H0YE41 TYK2 Tyrosine-protein kinase;Non-receptor tyrosine-protein kinase TYK2 1 LLAQAEGEPCY(1)IR 141.1 0.00010972 3353900.0 14487.0 26227.0 21712.0 16485.0 20847.0 28070.0 24381.0 22709.0 22491.0 17781.0 True False 14280.41272340958 26166.272992882066 19926.92317074371 17697.361892347908 19620.82044677894 26869.511534365934 25643.32888285078 23764.143043280343 19957.82673927039 20854.422158306792 0.6847666463739138 1.2547110053806714 0.9555250689507291 0.8486143494174277 0.9408469962790851 1.2884323205120884 1.2296350715541862 1.1395253660295996 0.9570069401956904 1.0 14.348065717626762 -6.7277954574404895 24.98289456340476 1.1383100128455197 0.9506800049499681 0.2474923770051798 0.16017530261626187 271.90494186734685 201907.1580497885 0.052704604138471285 0.05270177303528854 1.8715633954795138e-07 6.7277954574404895 -0.18763000789555162 LLAS(ph)PSSR ddPTM_PC-9_AZD4547_30min_R2 4 LLASPSSR 8 0 C9J470;E9PHA2;Q15003;C9JZP1 C9J470 NCAPH Condensin complex subunit 2 1 LLAS(0.74)PS(0.259)S(0.001)R;LLAS(0.73)PS(0.255)S(0.015)R;LLAS(0.932)PS(0.067)SR;LLAS(0.722)PS(0.273)S(0.005)R 93.598 0.007104899999999999 94497000.0 312267.0 292827.0 370264.0 527650.0 475180.0 426144.0 306834.0 413027.0 284418.0 364511.0 True False 411561.4104429045 387477.6012059128 365354.0574338006 406008.44461123494 409209.45920384885 399497.14831388724 334141.6315837793 349203.1675662597 299451.75482914463 351749.58083851263 1.1700409406652608 1.101572318244788 1.038676596466319 1.1542542386074155 1.1633545041570807 1.13574306858178 0.9499418045850718 0.9927607212318982 0.8513208576263299 1.0 18.424189178715793 -7.264038834471778 24.265817961110237 0.9479025562434834 1.1249446706976702 0.7429018212289208 0.051508907290934804 80.81009053265758 754350.804652381 0.021149688987846783 0.015013286581786233 5.444539657685496e-08 7.264038834471778 0.17704211445418683 LLAS(ph)PSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LLASPSSR 8 0 C9J470;E9PHA2;Q15003;C9JZP1 C9J470 NCAPH Condensin complex subunit 2 1 LLAS(0.714)PS(0.283)S(0.003)R;LLAS(0.945)PS(0.055)SR;LLAS(0.474)PS(0.474)S(0.052)R 96.03399999999999 0.006243899999999999 43534800.0 183366.0 176056.0 161834.0 179610.0 191223.0 166913.0 177341.0 142047.0 150021.0 120271.0 True False 214406.2421564163 193533.67616643067 165692.73631886294 169547.03400347673 153754.2258557915 158159.78844645657 160541.9766423454 138318.41676123725 152214.77331315188 142075.18023528752 1.5091041362843456 1.3621920158462857 1.1662328074788497 1.1933613860119248 1.0822032785822449 1.1132119500713051 1.1299790461393429 0.9735579186468124 1.0713678002102296 1.0 17.116295020017084 -1.5228787452813335 0.3992103937665046 1.0299618187648307 9.071292935907215 0.9196481289122898 0.04402973531239717 18.07412085653918 0.24004768158788978 0.03150075089906872 114.23816806929344 0.029999999999931203 1.5228787452813335 8.041331117142384 LLAS(ph)PSSR ddPTM_PC-9_Lapatinib_30min_R1 3 LLASPSSR 8 0 C9J470;E9PHA2;Q15003;C9JZP1 C9J470 NCAPH Condensin complex subunit 2 1 LLAS(0.975)PS(0.025)SR;LLAS(0.759)PS(0.241)SR;LLAS(0.704)PS(0.285)S(0.01)R 104.01 0.0038649 65299000.0 405279.0 337283.0 445652.0 303636.0 366365.0 396398.0 312787.0 290133.0 357501.0 271279.0 True False 399499.6471409337 336502.0419361063 409012.21282646834 325966.4043400026 344816.1310013034 379444.9815888705 328981.58038145455 303613.63836259034 317235.47272757563 318169.2136934536 1.255620059852301 1.0576197427458076 1.2855178792393762 1.0245064271179343 1.0837507721080875 1.1925886140399942 1.0339830700855248 0.9542520938405842 0.9970652692790775 1.0 18.279434720537765 -7.4445717233671 4.5036909088401655 0.9830711212256248 1.1426812291569626 0.4840931609291881 0.07862905520735322 0.19536397390689092 7.240934096702778 0.03385684346320485 0.021772049904218466 3.592760577179599e-08 7.4445717233671 0.15961010793133779 LLAS(ph)SPALPSSGAQAR ddPTM_PC-9_AZD4547_30min_R2 2 LLASSPALPSSGAQAR 16 0 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 LLAS(0.778)S(0.222)PALPSSGAQAR;LLAS(0.954)S(0.046)PALPSSGAQAR 224.34 1.3985e-28 33364000.0 72579.0 78160.0 108838.0 137085.0 117133.0 99083.0 92127.0 135688.0 88537.0 102498.0 True False 95657.6122630172 103423.69149789496 107394.7370065141 105482.17119213715 100871.10481275404 92887.32434666417 100326.12452635264 114720.53740005063 93216.88506813222 98909.57621796307 0.9671218492759523 1.0456388092289903 1.085787050283712 1.0664505422578126 1.0198315337078023 0.9391135610769588 1.014321649758846 1.1598526834979617 0.9424455005520791 1.0 16.59382258600752 -6.424170853997265 9.855363873078204 1.0167251789149123 1.0446340103166376 0.04328370772108814 0.06363251546821186 1.8033276093335295 169.2261900064972 0.02043753910574285 0.023166629655577396 3.7655563064625687e-07 6.424170853997265 0.027908831401725287 LLAS(ph)SPALPSSGAQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLASSPALPSSGAQAR 16 0 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 LLAS(0.5)S(0.5)PALPSSGAQAR;LLAS(0.64)S(0.36)PALPSSGAQAR 217.39 3.9611000000000003e-22 20227700.0 100345.0 118869.0 118672.0 103150.0 137186.0 105053.0 99358.0 90176.0 87183.0 73527.0 True False 117331.42659591019 130669.52874214674 121501.59054606639 97370.83991681196 110305.38809794108 99543.83574476285 89946.09095037349 87808.97554936985 88457.88644096826 86856.86306058818 1.3508595919940611 1.5044237627025103 1.3988715026619292 1.1210494655890304 1.269967440811166 1.1460675902527668 1.035566883041014 1.0109618567287828 1.0184328943501364 1.0 16.40635222862658 -6.218595214927805 0.5907930908689022 0.9898034702028857 1.48768223386995 0.8253184743267156 0.0727150062692153 0.4124926536506423 0.2934312889836214 0.05326200305080878 0.11256973779671875 6.045118033614077e-07 6.218595214927805 0.4978787636670643 LLAS(ph)SPALPSSGAQAR ddPTM_PC-9_Lapatinib_30min_R1 1 LLASSPALPSSGAQAR 16 0 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 LLAS(0.5)S(0.5)PALPSSGAQAR 247.17 4.61e-47 12664000.0 79693.0 75780.0 91528.0 66910.0 52107.0 65907.0 54683.0 43442.0 57584.0 43342.0 True False 78556.5632060935 75604.53606590924 84002.9211482972 71830.78460521695 49042.168706303564 63088.31124672085 57514.21817402605 45460.47391281803 51098.283533597685 50833.60695041518 1.5453666957514982 1.4872943432807446 1.6525075867670869 1.413057009219966 0.9647587816095945 1.2410748524742563 1.1314211527450209 0.8942995911575135 1.0052067244301723 1.0 15.633494981865502 -6.123401332618254 3.9604273703289494 1.0494595824779833 1.5526158574950002 0.857029108726528 0.09815536861568644 0.09004340549164858 2.43800069648829 0.031496327099983304 0.04192483317303511 7.526597075415198e-07 6.123401332618254 0.5031562750170169 LLASPSS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLASPSSR 8 0 C9J470;E9PHA2;Q15003;C9JZP1 C9J470 NCAPH Condensin complex subunit 2 1 LLAS(0.275)PS(0.275)S(0.449)R 83.647 0.014759 7158100.0 30174.0 38233.0 39160.0 44742.0 40808.0 29332.0 32981.0 28600.0 26413.0 25278.0 True False 35281.8622363345 42028.519566905576 40093.722915127 42235.25079552112 32811.965342679105 27793.778283965104 29856.800918237772 27849.280304204844 26799.240156513297 29860.70129946212 1.1815483461860299 1.4074860180079776 1.342691938579795 1.414409205328406 1.0988343848196944 0.9307811630152757 0.9998693807896462 0.9326398608296079 0.8974752430545238 1.0 14.865960428122209 -6.465907006003568 3.460697103344418 0.9529005029488357 1.3408654819127341 0.8781995286289201 0.0673492409871687 0.07662257574497194 1.8257037705933363 0.02201454942746994 0.024290550293254262 3.420526772460298e-07 6.465907006003568 0.3879649789638985 LLASQGSQGAPLLST(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 LLASQGSQGAPLLSTPK 17 0 H3BRB3;Q14807-2;Q14807 H3BRB3 KIF22 Kinesin-like protein;Kinesin-like protein KIF22 1 LLASQGSQGAPLLS(0.237)T(0.763)PK;LLASQGSQGAPLLS(0.034)T(0.966)PK 186.96 6.262299999999999e-08 21903000.0 167499.0 139767.0 173028.0 196605.0 227870.0 210850.0 173903.0 182109.0 176529.0 193957.0 True False 220760.19780436633 184943.94945734774 170733.53566551325 151280.75476697038 196234.18382251138 197665.51616820417 189380.03010524932 153968.2384985102 185859.96254890366 187166.62446591587 1.1794848490445904 0.988124618826083 0.9122007524188952 0.808267794531495 1.0484464545026122 1.0560938240578261 1.0118258564829572 0.8226265710452492 0.9930187237134783 1.0 17.513963671054867 -4.773197259283554 3.818050475980019 0.9534882175758894 1.2040543552257155 0.3981528172332036 0.0816358028333083 0.2743529320193492 7.148348561221826 0.02175113241240227 0.19625128020183066 1.6857871563477634e-05 4.773197259283554 0.25056613764982605 LLASQGSQGAPLLST(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLASQGSQGAPLLSTPK 17 0 H3BRB3;Q14807-2;Q14807 H3BRB3 KIF22 Kinesin-like protein;Kinesin-like protein KIF22 1 LLASQGSQGAPLLS(0.08)T(0.92)PK;LLASQGSQGAPLLS(0.091)T(0.909)PK 207.05 5.6861e-17 20008000.0 99555.0 106090.0 90340.0 93630.0 115281.0 97242.0 106812.0 90519.0 86098.0 71944.0 True False 116407.69519912107 116621.9140756158 92494.04821635783 88384.21465255543 92692.51560158299 92142.45833524247 96693.99410808668 88142.97216280844 87357.02036858673 84986.87769160936 1.3697137530046457 1.3722343642132617 1.0883332901343854 1.0399748414487462 1.0906685610681564 1.0841962999228947 1.1377520475450194 1.0371362562894892 1.0278883368980547 1.0 16.374952480203163 -5.274334307438235 5.25294711962802 1.0669505580584424 1.3743599529770263 0.9174963067478225 0.036936717405707954 0.040963215191501826 3.7949339852409247 0.009845050373905456 0.02325700773330045 5.316988151970457e-06 5.274334307438235 0.3074093949185839 LLASQGSQGAPLLST(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 LLASQGSQGAPLLSTPK 17 0 H3BRB3;Q14807-2;Q14807 H3BRB3 KIF22 Kinesin-like protein;Kinesin-like protein KIF22 1 LLASQGSQGAPLLS(0.296)T(0.704)PK;LLASQGSQGAPLLS(0.01)T(0.99)PK 197.51 7.1017e-12 17401200.0 138340.0 120815.0 99732.0 115526.0 108307.0 105810.0 81347.0 83214.0 96482.0 70831.0 True False 136367.24623155082 120535.26029035173 91532.41993665305 124022.1674234386 101936.59519975474 101284.75295515706 85558.74962607199 87080.4262276424 85615.18115949878 83074.04397362519 1.6415144816453795 1.450937675895734 1.1018173133080325 1.4929111608291736 1.2270570965838397 1.2192105754152707 1.029909530505529 1.0482266429125466 1.0305888225049014 1.0 16.342110164849288 -1.5228787530828942 0.22109203051921578 0.9510674092383017 4.439508920260003 0.7263382166805763 0.11331996140331996 27.763296885578413 0.35590522743638325 0.18149182486646684 34.6079112257758 0.029999999461018487 1.5228787530828942 3.4884415110217017 LLASS(ph)PALPSSGAQAR ddPTM_PC-9_Lapatinib_30min_R1 1 LLASSPALPSSGAQAR 16 0 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 LLAS(0.151)S(0.849)PALPSSGAQAR 176.43 9.9356e-06 16981000.0 65312.0 58632.0 73054.0 59361.0 53335.0 54131.0 45217.0 39407.0 43424.0 32956.0 True False 64380.638903246065 58496.24120633935 67047.78211659497 63726.60596249098 50197.94016064446 51815.94331552412 47558.1150115198 41237.993082326306 38533.13184500811 38652.4006888903 1.6656310541081274 1.5133921868701077 1.7346343544416953 1.6487101661658923 1.2987017433841475 1.3405620968432463 1.2304052054699215 1.0668934489799793 0.996914322480454 1.0 15.238270401834042 -6.962790001522214 0.7531778632985849 0.988549393862792 1.6611401303988418 0.9037863019595096 0.08252461771693233 0.2019689557066597 0.24181897578568307 0.0660778774610994 0.05321298152196264 1.0894567612208155e-07 6.962790001522214 0.6725907365360498 LLAVAATAPPDAPNREEVFDER ddPTM_PC-9_Lapatinib_30min_R1 1 LLAVAATAPPDAPNREEVFDER 22 1 P18206;P18206-2 P18206 VCL Vinculin 0 76.76100000000001 0.001008 6431500.0 17404.0 20839.0 28455.0 19535.0 22530.0 24617.0 19867.0 20558.0 24651.0 18711.0 False True 17155.81576849728 20790.74857584434 26115.539739476422 20971.669066849638 21204.829695684253 23564.188295029777 20895.616050022432 21513.199730668784 21874.54479346201 21945.17141915968 0.7817581116508866 0.9473951321105905 1.190035805173785 0.9556393370680119 0.9662640264076927 1.0737755401835951 0.9521737447800972 0.9803158662905793 0.9967816781036393 1.0 14.421615919038675 -4.8328315868389105 4.0440349995460325 1.0128189281046565 0.7731785865803256 0.5128864231568719 0.06813904509500379 0.16999386444111667 4.7794669900835665 0.01709520240331069 0.10389689863525349 1.4694960166131736e-05 4.8328315868389105 -0.2396403415243309 LLCGLLAER ddPTM_PC-9_Lapatinib_30min_R1 1 LLCGLLAER 9 0 P14174 P14174 MIF Macrophage migration inhibitory factor 0 116.9 0.0087098 10705000.0 35545.0 37856.0 35543.0 29372.0 35913.0 37343.0 32229.0 29109.0 37931.0 28070.0 False True 35038.121781845315 37768.34675786572 32620.79173994764 31532.114862119677 33800.66794767459 35745.926940784724 33897.65992229188 30461.510407629015 33658.811348862415 32921.86209907607 1.0642812875043492 1.147211741675015 0.9908550021191882 0.9577864935836848 1.026693685975411 1.0857808356407614 1.0296398126047432 0.9252669340500002 1.0223847985137824 1.0 15.00675831813788 -5.271108430039857 24.97541266166421 1.0050139420139366 1.1057465155846251 0.4471714964566528 0.04489526469392464 561.7859919876014 1451108.9088820564 0.01245728572058445 0.02647933671641659 5.356629021848712e-06 5.271108430039857 0.10073257357068854 LLCYIS(ph)LRSATR ddPTM_PC-9_AZD4547_30min_R2 2 LLCYISLRSATR 12 1 Q9UK61-3;Q9UK61;Q9UK61-4 Q9UK61-3 FAM208A Protein FAM208A 1 LLCY(0.004)IS(0.929)LRS(0.052)AT(0.016)R;LLCY(0.016)IS(0.95)LRS(0.033)ATR 70.942 0.028023000000000003 2714800.0 5466.7 7641.5 10740.9 10973.5 10933.7 8950.0 8684.3 12091.099999999999 8331.5 7998.400000000001 True False 7204.996885576225 10111.465437322991 10598.468648020613 8443.729113884945 9415.744484399864 8390.355085157355 9457.185876281701 10222.698320837162 8771.886080905644 7718.378450523486 0.9334858262991184 1.3100504856220412 1.3731470562060597 1.0939770792545502 1.2199122580937005 1.0870618924611415 1.2252814418085813 1.3244619172753604 1.1364933887519737 1.0 12.914082069057926 LLDEDEIR ddPTM_PC-9_AZD4547_30min_R2 2 LLDEDEIR 8 0 O43719;Q5H919;Q5H918 O43719 HTATSF1 HIV Tat-specific factor 1 0 ; 143.89 0.0077832 2685100.0 14857.7 14239.0 19294.1 29151.0 23076.1 22119.0 19536.6 27328.0 20030.8 20081.0 False True 19582.139540641685 18841.478291178704 19038.247627459023 22430.687328460375 19872.38183748041 20735.89543336261 21275.319552590896 23105.08553496688 21089.587194311305 19377.970302180693 1.0105361518919251 0.9723143341311853 0.9824686141312003 1.1575354373381481 1.0255141032620987 1.0700757153616394 1.0979126926516491 1.1923377513054996 1.0883279758116873 1.0 14.242129846673524 -5.7405651832219196 24.978225475262825 1.0950396353026626 0.9868270904589845 0.4293112188224244 0.05357912148614033 216.48069625474278 259040.5469869242 0.01459256670568921 0.025240504938251807 1.8173342720783323e-06 5.7405651832219196 -0.10821254484367804 LLDEDEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLDEDEIR 8 0 O43719;Q5H919;Q5H918 O43719 HTATSF1 HIV Tat-specific factor 1 0 ; 118.74 0.016079 565180.0 12766.0 12140.7 16462.9 16337.8 18175.7 14647.5 15954.8 12976.0 14489.6 14134.2 False True 14927.031660006836 13345.948460908921 16855.437971895935 15422.446033862268 14614.302060354168 13879.359314549944 14443.445841251028 12635.393749208464 14701.482988369942 16696.618573734355 0.8940152518958973 0.7993204373670959 1.009512069612192 0.9236867911759988 0.8752851360780378 0.8312676757426636 0.8650521527737467 0.7567636341100437 0.8805066081761619 1.0 14.027268334891973 -6.4985027283899885 5.381935710943646 0.8514180811885094 0.9058703075867343 0.04236166938891317 0.0741859704197 0.4467296103204208 38.354278979976804 0.023588290216318402 0.025632015610553043 3.173198728628125e-07 6.4985027283899885 0.05445222639822489 LLDEDEIR ddPTM_PC-9_Lapatinib_30min_R1 2 LLDEDEIR 8 0 O43719;Q5H919;Q5H918 O43719 HTATSF1 HIV Tat-specific factor 1 0 ; 114.5 0.016932 2928700.0 8772.3 12257.2 14181.1 14080.3 12357.7 14259.2 14568.3 14601.9 15313.699999999999 12407.6 False True 8647.205393357199 12228.819206480128 13015.184698629035 15115.81223250386 11630.844382172985 13649.367255818697 15322.575290760633 15280.357580856718 13588.909845590008 14552.237127912225 0.5942182852952035 0.8403394680137793 0.8943768978080343 1.0387277296018396 0.7992478599640326 0.9379566272761073 1.0529360644742962 1.0500349497155943 0.9338021175813245 1.0 13.82895333648022 -4.309407124394569 0.9982349851706029 0.9746027761564767 7.914863954380328e-19 0.7114248806311304 0.07266339020239083 2.4983156796721984 1.0486208038340294 0.024725361103060114 3.2722358684954096 4.904478958144824e-05 4.309407124394569 -0.9746027761564767 LLDEEEATDNDLR ddPTM_PC-9_AZD4547_30min_R2 2 LLDEEEATDNDLR 13 0 Q8WUM4;Q8WUM4-2 Q8WUM4 PDCD6IP Programmed cell death 6-interacting protein 0 ; 169.65 0.001151 8280200.0 8149.9 6911.8 11546.5 15442.9 12865.2 11751.7 10178.4 13626.7 11301.3 12275.3 False True 10741.398671549143 9145.904182384225 11393.385865650926 11882.777995426603 11079.089049516726 11016.864341256269 11084.257881826486 11521.006625414708 11898.663645938783 11845.545483310527 0.9067880146746266 0.7720964978160025 0.9618287213284809 1.0031431656877712 0.9352958093087668 0.9300428044262034 0.9357321617179524 0.9726024556359123 1.0044842310303983 1.0 13.53205701526959 -5.28454274351962 23.78654407736615 0.9645073218969564 0.8394422781805948 0.6165170605261541 0.04045163414352308 232.3282613393877 239198.1594068746 0.010324540111751672 0.021520626219687578 5.193465565964848e-06 5.28454274351962 -0.12506504371636162 LLDEEEATDNDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLDEEEATDNDLR 13 0 Q8WUM4;Q8WUM4-2 Q8WUM4 PDCD6IP Programmed cell death 6-interacting protein 0 ; 132.56 0.00025143 5220500.0 9827.5 9571.7 12974.1 10763.2 13953.599999999999 12030.900000000001 11906.8 10983.400000000001 9378.6 10085.5 False True 11491.10164802736 10521.915118838451 13283.451748548257 10160.17279876521 11219.492246755713 11399.978424810985 10778.901706233091 10695.097387874246 9515.744282431968 11913.92131322593 0.9645104534365869 0.8831613741781071 1.1149521135247031 0.8527983802852683 0.9417128040203426 0.9568619873421184 0.9047316515568365 0.8976975008221149 0.79870800152661 1.0 13.540360715340544 -7.404254024104038 2.7894398993589014 0.8870558363289592 0.9518644012886724 0.08890239183752002 0.07883131774567018 0.6217362029805632 9.344580083607967 0.037346711786317044 0.022752697729980266 3.942266466835007e-08 7.404254024104038 0.06480856495971321 LLDEEEATDNDLR ddPTM_PC-9_Lapatinib_30min_R1 3 LLDEEEATDNDLR 13 0 Q8WUM4;Q8WUM4-2 Q8WUM4 PDCD6IP Programmed cell death 6-interacting protein 0 ;; 144.7 0.00033288 12890500.0 28157.4 29932.5 30298.1 29808.7 28522.6 27246.0 25218.2 27210.699999999997 29082.0 27845.8 False True 27755.870312565243 29863.193135297333 27807.10717204817 32000.93123690819 26844.956745589167 26080.752093528125 26523.875002399745 28475.00845954415 25806.47891296345 32658.909427803774 0.8498713153273763 0.9143965202302089 0.8514401631664688 0.9798530262515311 0.8219795827822417 0.7985800062057365 0.8121482152070565 0.8718909773301338 0.7901818941631104 1.0 14.995188995636797 LLDESESAAS(ph)SR ddPTM_PC-9_AZD4547_30min_R2 1 LLDESESAASSR 12 0 Q8N108-17;Q8N108;Q8N108-13;Q8N108-12;Q8N108-19;Q8N108-16;Q8N108-14;Q8N108-18;Q8N108-15 Q8N108-17 MIER1 Mesoderm induction early response protein 1 1 LLDES(0.001)ES(0.014)AAS(0.812)S(0.173)R 71.513 0.027222000000000003 1626500.0 7743.0 7774.9 11785.0 15867.0 12498.0 11681.0 9120.7 11644.0 7863.8 11825.0 True False 10205.112935594909 10287.984378543804 11628.723199817789 12209.108292706287 10762.868431183351 10950.585223432741 9932.424630862879 9844.687352501252 8279.46441373412 11411.010349249875 0.8943215914501175 0.9015840020879575 1.019079191404136 1.0699410410673125 0.9432003040721867 0.9596508011363428 0.870424644870803 0.86273581840616 0.7255680400183309 1.0 13.478138915375885 -7.304900649713989 2.447389699217441 0.8466553117274412 0.9703190804185391 0.27225863053343446 0.07871109124773544 0.36928470287782533 4.343559647432876 0.03866425026338278 0.024754928809603463 4.95563544187904e-08 7.304900649713989 0.12366376869109785 LLDESESAAS(ph)SR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLDESESAASSR 12 0 Q8N108-17;Q8N108;Q8N108-13;Q8N108-12;Q8N108-19;Q8N108-16;Q8N108-14;Q8N108-18;Q8N108-15 Q8N108-17 MIER1 Mesoderm induction early response protein 1 1 LLDESES(0.012)AAS(0.886)S(0.102)R 107.99 0.0023998 0.0 14966.0 24457.0 17333.0 18459.0 19120.0 13324.0 21180.0 14467.0 11499.0 13675.0 True False 17499.448208026195 26884.929329317874 17746.28445576855 17424.80207488545 15373.573254068438 12625.265984438529 19173.677070079015 14087.256579053548 11667.15112102928 16154.169248759557 1.0832775080259816 1.664271861667062 1.098557541554249 1.0786566493491123 0.9516783572915049 0.7815484529114981 1.1869181741766954 0.8720508224299605 0.7222377666945129 1.0 13.979618939406079 -5.665027111605715 2.126225215860273 0.9279450303300256 1.3725061049448906 0.4555563270945481 0.1842180668208032 0.25992371197381064 2.3760436625864036 0.05282956684385964 0.11220552022218812 2.16258351638942e-06 5.665027111605715 0.44456107461486494 LLDEVFFSEK ddPTM_PC-9_Lapatinib_30min_R1 1 LLDEVFFSEK 10 0 P25789;H0YN18;H0YMI6;H0YMA1;H0YMZ1;H0YL69;H0YLS6;H0YLC2;H0YKT8 P25789 PSMA4 Proteasome subunit alpha type-4;Proteasome subunit alpha type;Proteasome subunit beta type 0 147.95 3.2788e-08 0.0 10622.0 10832.0 12462.0 10519.0 9381.5 9294.2 11740.0 9102.1 10694.0 10839.0 False True 10470.528332163769 10806.919169516095 11437.422464711122 11292.602350355339 8829.69861473866 8896.708731838402 12347.83975573882 9525.016794849706 9489.529107187647 12712.506707940336 0.8236399455053024 0.8501013543431214 0.8996984408721856 0.8883065008179611 0.6945678627822125 0.6998390589860176 0.9713143158482078 0.7492634626418959 0.7464719055967467 1.0 13.633960914891592 LLDFGS(ph)LSNLQVTQPTVGMNFK ddPTM_PC-9_AZD4547_30min_R2 3 LLDFGSLSNLQVTQPTVGMNFK 22 0 H3BNC9;P08708 H3BNC9 RPS17 40S ribosomal protein S17 1 LLDFGS(0.974)LS(0.026)NLQVTQPTVGMNFK;LLDFGS(0.987)LS(0.013)NLQVTQPTVGMNFK;LLDFGS(0.988)LS(0.012)NLQVTQPTVGMNFK 150.73 1.7595e-05 30144200.0 142343.0 136296.0 197763.0 263499.0 202711.0 190556.0 173160.0 199455.0 160823.0 172691.0 True False 187605.1130816721 180351.01658645223 195140.53340395147 202753.3765689681 174568.07669656005 178640.50319633994 188570.904544631 168633.81276993628 169323.77545333814 166645.14065304957 1.1257760793173117 1.0822458781557747 1.1709944414774656 1.2166774006995789 1.0475437568264039 1.0719814721046343 1.131571576618788 1.0119335739949782 1.0160738848417152 1.0 17.3464197237304 -7.612883724881371 0.7669064121813437 0.9935655479009308 1.1363101158315092 0.5250084938141627 0.047448867230417094 0.5621765752254246 0.6221711870353039 0.04516762150234978 0.0224715557837013 2.4384635890179614e-08 7.612883724881371 0.14274456793057844 LLDFGS(ph)LSNLQVTQPTVGMNFK ddPTM_PC-9_Lapatinib_30min_R1 3 LLDFGSLSNLQVTQPTVGMNFK 22 0 H3BNC9;P08708 H3BNC9 RPS17 40S ribosomal protein S17 1 LLDFGS(0.977)LS(0.023)NLQVTQPTVGMNFK;LLDFGS(0.991)LS(0.009)NLQVTQPTVGMNFK;LLDFGS(0.908)LS(0.092)NLQVTQPTVGMNFK 122.51 3.5952e-07 33861000.0 102870.0 97395.0 101686.0 103559.0 95944.0 91822.0 92026.0 70738.0 90132.0 72753.0 True False 101403.05493595231 97169.48786143088 93325.76959931101 111175.07432269708 90300.76255316156 87894.98710753652 96790.65599332379 74024.74572176507 79980.38502796307 85328.25911272093 1.1883877157507239 1.13877265130966 1.0937263993166104 1.3029103778600688 1.0582749899288562 1.0300806323896152 1.1343329513550806 0.8675290752618823 0.9373258737449082 1.0 16.38073599366075 -7.214243265396473 1.0169398748095653 0.9361050454516769 1.1662399679559503 0.5458128742784061 0.08049453026554938 0.41024111556330317 0.8337187783681705 0.057358050876338496 0.03398296606959955 6.105999081078044e-08 7.214243265396473 0.23013492250427336 LLDMIET(ph)LK ddPTM_PC-9_AZD4547_30min_R2 1 LLDMIETLK 9 0 E6ZCI6;C0MHM2;Q86VZ5 E6ZCI6 SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 1 LLDMIET(1)LK 77.533 0.032057999999999996 0.0 16074.0 14569.0 19106.0 22780.0 21581.0 20834.0 20719.0 20846.0 21819.0 18482.0 True False 21185.19764003004 19278.144337676982 18852.641956361364 17528.422947491606 18584.850665175876 19531.246686499257 22562.95086197858 17624.729693425044 22972.307795628654 17834.950805482986 1.1878472708496113 1.080919400784123 1.0570616180542258 0.9828130808245827 1.042046645817624 1.095110768710098 1.2650974543222215 0.9882129693347226 1.2880499669540044 1.0 14.122419615943823 -7.007833201563723 24.15924387902057 1.1408930210845283 1.0655007633715419 0.0823174471452992 0.1014440335688584 541.4948901175374 1670086.9779008715 0.035087777148632884 0.029615736917527887 9.821250730063683e-08 7.007833201563723 -0.07539225771298641 LLDPEDVDVPQPDEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLDPEDVDVPQPDEK 15 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 108.56 0.0056588 0.0 9835.7 10047.0 8850.1 11492.0 14316.0 9471.9 7864.1 7891.8 9873.1 8503.9 False True 11500.689746069975 11044.399761690182 9061.119948191152 10848.140497566697 11510.882568265879 8975.176889673023 7119.155516846482 7684.648612053275 10017.47540942988 10045.589753164642 1.1448496333873215 1.0994277123661043 0.9019997999954801 1.0798908540087684 1.1458642898133111 0.8934444975563123 0.7086846757407895 0.7649773483565159 0.997201324718053 1.0 13.294274643370803 -6.891975903659191 5.797933534661259 0.8420363197693214 1.0655928251227584 0.4641883683898248 0.10674052935687434 0.18201367712458896 8.66052410940452 0.038753600585914344 0.03415501481120186 1.2824017332997982e-07 6.891975903659191 0.22355650535343707 LLDPEDVDVPQPDEK ddPTM_PC-9_Lapatinib_30min_R1 2 LLDPEDVDVPQPDEK 15 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 177.42 0.00021035 6677400.0 121856.0 109272.0 119407.0 115229.0 113484.0 101813.0 119883.0 111697.0 103196.0 113612.0 False True 120118.31109434667 109018.98739765151 109589.81738434959 123703.3250526756 106809.09423812841 97458.69532769508 126089.9551479761 116886.85038994598 91572.97977794429 133249.6828215261 0.9014528856720243 0.8181556990546157 0.8224396115909228 0.9283573696634096 0.8015710955288946 0.7313990792625805 0.946268332337123 0.8772017157181798 0.6872285009533317 1.0 17.023772573332288 -10.76487035384205 5.573463405430506 1.0000096984159674 0.8372828168382019 0.2848224422602045 0.0784046497326997 9.295365772390027e-06 1.2643100253019278e-06 0.07468375227211825 0.018112391454660155 1.718421295974216e-11 10.76487035384205 -0.1627268815777655 LLDVVHPAAK ddPTM_PC-9_Lapatinib_30min_R1 1 LLDVVHPAAK 10 0 Q99832-3;Q99832;F8WAM2 Q99832-3 CCT7 T-complex protein 1 subunit eta 0 66.595 0.038432999999999995 6191000.0 123370.0 113010.0 115680.0 110580.0 110590.0 111860.0 117080.0 104310.0 100430.0 107720.0 False True 121610.7211767126 112748.33228831345 106169.2369377131 118712.42208406639 104085.31362830546 107076.00855839583 123141.82952316014 109156.62340237666 89118.51582521563 126339.25847212218 0.9625727002628168 0.8924251547130326 0.8403503251615192 0.9396320947242324 0.8238556636080998 0.8475276003145377 0.9746917230033642 0.8639960747154692 0.7053905247107365 1.0 16.946943484127026 -4.79788836711181 3.6062209282149253 0.8723630369622352 0.9711658558819173 0.09829347634579988 0.07954079032195002 0.6202946032867838 13.72679961897473 0.019529663425379054 0.1618358432600318 1.592618047712737e-05 4.79788836711181 0.09880281891968212 LLEAQSHFR ddPTM_PC-9_AZD4547_30min_R2 2 LLEAQSHFR 9 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2;A0A1B0GUH3 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 ; 82.831 0.012759999999999999 9279400.0 256244.0 259076.0 287540.0 405730.0 406760.0 362130.0 307830.0 351280.0 359960.0 402300.0 False True 337724.26179369516 342817.2504926902 283727.0317247019 312195.2169660124 350288.39518868196 339485.95385341137 335226.2736542716 296997.74761135696 378986.75072709523 388215.5994505896 0.869939956744781 0.883058926477586 0.7308491264293295 0.8041799902112053 0.9023037602930356 0.8744778786165692 0.8635054184548236 0.7650330075135415 0.9762275170380705 1.0 18.56649856466212 -8.37247469963409 6.168682915634547 0.996972431263661 0.8381802535633297 0.5745719070816272 0.052213024358261834 0.18092688662169737 8.384081577058607 0.05273833302996377 0.01368526651331974 4.24155692908885e-09 8.37247469963409 -0.15879217770033127 LLEAQSHFR ddPTM_PC-9_Lapatinib_30min_R1 2 LLEAQSHFR 9 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2;A0A1B0GUH3 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 ; 133.99 0.00095714 5853800.0 233402.0 224077.0 200874.0 212480.0 235296.0 209493.0 174828.0 168863.0 205936.0 169430.0 False True 230073.64467931585 223558.16347375038 184358.91511606323 228106.48801250078 221456.35188973494 200533.47274203508 183879.73840002617 176708.9914446897 182741.31907778146 198715.74974871642 1.157802765861552 1.125014820196427 0.9277519036573199 1.1479034163167743 1.1144378448601828 1.0091473524147796 0.9253405360800493 0.8892550875717948 0.9196116528703173 1.0 17.6003466962136 -7.034765870766819 3.0600328442683242 0.9247908510621893 1.0895191634651953 0.5677206475185903 0.06588883509748321 0.19798426072494832 3.7338044215598716 0.02735225849024984 0.021645876457045948 9.230689217893568e-08 7.034765870766819 0.164728312403006 LLEDGEDFNLGDALDS(ph)SNSMQTIQK ddPTM_PC-9_AZD4547_30min_R2 1 LLEDGEDFNLGDALDSSNSMQTIQK 25 0 P05783 P05783 KRT18 Keratin, type I cytoskeletal 18 1 LLEDGEDFNLGDALDS(0.327)S(0.327)NS(0.327)MQT(0.018)IQK 103.84 5.4507e-07 3458500.0 15027.0 11371.0 13703.0 18039.0 16673.0 13896.0 16031.0 17607.0 14680.0 11612.0 True False 19805.27341898291 15046.453377975487 13521.289266618858 13880.387249771778 14358.24174692911 13027.080923278936 17457.727943837974 14886.242718609556 15455.954830186018 11205.467414417717 1.7674651745004495 1.3427778441991358 1.2066689203184373 1.238715596273327 1.2813603588240166 1.1625647053792159 1.5579651698755264 1.3284803005589845 1.3793226340830134 1.0 13.451915208888426 -4.766805644621899 4.170249886879375 1.286121989235076 1.813316202175421 0.534610893486187 0.13790887487168493 0.17877351573702774 6.166733792124823 0.033868102711383574 0.28822705187359376 1.710780752057191e-05 4.766805644621899 0.5271942129403451 LLEDGEDFNLGDALDS(ph)SNSMQTIQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LLEDGEDFNLGDALDSSNSMQTIQK 25 0 P05783 P05783 KRT18 Keratin, type I cytoskeletal 18 1 LLEDGEDFNLGDALDS(0.337)S(0.268)NS(0.337)MQT(0.057)IQK;LLEDGEDFNLGDALDS(0.333)S(0.333)NS(0.333)MQT(0.001)IQK;LLEDGEDFNLGDALDS(0.332)S(0.332)NS(0.332)MQT(0.003)IQK 113.08 4.0782e-08 9095400.0 36202.8 39697.7 33546.4 37728.9 37526.6 32318.6 33237.4 29147.9 28925.2 22117.199999999997 True False 42331.21900210683 43638.62530304051 34346.273401430466 35615.072051744195 30173.53211695213 30623.755722356284 30088.91285406252 28382.79850975287 29348.176328897844 26126.873280341126 1.6202175647997836 1.6702582369806918 1.3145956285275795 1.3631586018577415 1.154884926075554 1.1721171298901192 1.1516461434634273 1.086345013626609 1.1232946251926959 1.0 14.673246860776258 -5.151940442046044 0.5267277863639186 1.0702448526772872 1.96504167764804 0.9094375007325778 0.06442625335830021 0.7715827771259043 0.21646502937125447 0.03852827204094979 0.40558749561732255 7.047897152683685e-06 5.151940442046044 0.8947968249707527 LLEDGEDFNLGDALDSS(ph)NSMQTIQK ddPTM_PC-9_AZD4547_30min_R2 1 LLEDGEDFNLGDALDSSNSMQTIQK 25 0 P05783 P05783 KRT18 Keratin, type I cytoskeletal 18 1 LLEDGEDFNLGDALDS(0.263)S(0.616)NS(0.121)MQTIQK 110.33 1.9084e-07 3564500.0 12116.0 14339.0 18364.0 22497.0 16095.0 16745.0 16363.0 21123.0 18003.0 18966.0 True False 15968.635971544358 18973.801335572127 18120.481361175564 17310.664225185184 13860.487069922869 15697.932502900543 17819.27530066875 17858.925708251812 18954.601826147064 18302.006112801104 0.8725074111069878 1.0367060976064884 0.9900817019453089 0.9458342499993737 0.757320644769555 0.857716493271239 0.9736241585126171 0.9757906099572666 1.035657059085425 1.0 14.15971417288742 -7.476136415992061 5.253271831780119 0.999629897888568 0.9138544834608952 0.25638057069255527 0.0729419280271854 0.35403710413331074 23.02878940041306 0.03639576362244208 0.02338098579688413 3.340900826975677e-08 7.476136415992061 -0.08577541442767289 LLEDGEDFNLGDALDSS(ph)NSMQTIQK ddPTM_PC-9_Lapatinib_30min_R1 1 LLEDGEDFNLGDALDSSNSMQTIQK 25 0 P05783 P05783 KRT18 Keratin, type I cytoskeletal 18 1 LLEDGEDFNLGDALDS(0.203)S(0.341)NS(0.341)MQT(0.115)IQK 102.21 7.8757e-07 2529800.0 11440.0 8719.4 16790.0 13500.0 14236.0 12416.0 9217.9 12376.0 15415.0 16471.0 True False 11276.863502160944 8699.21076501834 15409.591011274271 14492.835034679814 13398.666469052867 11884.996623109628 9695.157758468902 12951.03414080926 13678.80037285372 19317.99040377207 0.5837493065510065 0.4503165486260784 0.7976808502951406 0.7502247765818288 0.6935849013796288 0.6152294506155743 0.5018719626538279 0.6704131159667838 0.7080860942027785 1.0 14.237657402019895 -8.790460510276054 1.9620561832932064 0.9996931903500839 0.6333237623885729 0.5501916480247147 0.09950149397442268 0.9317930040956202 5.5352819691533295 0.10334760621892976 0.028678351545390265 1.6200912995966092e-09 8.790460510276054 -0.36636942796151095 LLEDGEDFNLGDALDSSNSMQTIQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLEDGEDFNLGDALDSSNSMQTIQK 25 0 P05783 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ; 173.78 8.627200000000001e-15 4599400.0 59173.0 62632.0 63121.0 68076.0 71479.0 63247.0 65088.0 51418.0 62155.0 57078.0 False True 69189.82017997678 68849.69103953202 64626.04402772551 64261.922425369834 57473.20306629485 59930.215980019835 58922.393443687586 50068.33198187426 63063.89928929256 67425.78957080055 1.0261625502705298 1.0211180540531348 0.9584766368937339 0.9530763055861808 0.8523919917310724 0.8888322459626523 0.8738851086321509 0.7425694574818428 0.9353082802697062 1.0 16.04101289038495 -5.792112998720388 1.249238601603531 0.8674957976445717 1.0283154576560707 0.4189907536723003 0.06358472078296747 0.4167011674779067 1.2921091496947512 0.02169901667459994 0.053597030838921596 1.6139385728549786e-06 5.792112998720388 0.16081966001149894 LLEDGEDFNLGDALDSSNSMQTIQK ddPTM_PC-9_Lapatinib_30min_R1 5 LLEDGEDFNLGDALDSSNSMQTIQK 25 0 P05783 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ;;;; 212.0 1.1554e-31 23546000.0 173455.7 166341.9 190237.0 176015.8 177601.0 165787.4 178662.1 160141.3 170907.0 174788.0 False True 170982.18991012016 165956.74555056615 174596.44819605592 188960.58910349628 167154.85835700066 158697.05937130513 187912.34933763085 167582.04942255814 151657.65392950433 204999.8729096294 0.8340599800542055 0.809545602126911 0.8516905192083886 0.9217595426841863 0.8153900584645141 0.7741324768589684 0.9166461748025996 0.8174739186127874 0.7397938924399233 1.0 17.645263489764098 -10.56428004629501 4.352561425155942 1.0000104747556764 0.8337680820970214 0.4730464973536498 0.05339485758987445 76778471.18924366 98139723.39423826 10921.638771297145 0.013537224277457193 2.7272186221477255e-11 10.56428004629501 -0.16624239265865504 LLEEHAK ddPTM_PC-9_AZD4547_30min_R2 2 LLEEHAK 7 0 A0A2R8Y5M6;P51572;P51572-2 A0A2R8Y5M6 BCAP31 B-cell receptor-associated protein 31 0 ; 101.28 0.0094404 5199000.0 79315.0 80732.0 141631.0 122227.0 109993.0 69537.0 104643.0 102252.0 90804.0 80729.0 False True 104535.52014551336 106827.04019969379 139752.88039994857 94049.45353832554 94722.37056738262 65188.84039738398 113956.0242796482 86451.30291720721 95603.71405995995 77902.70228199507 1.3418728373132918 1.3712879922059358 1.7939413692488606 1.2072681791946303 1.2159060955870709 0.8367981916905914 1.4627993759079885 1.109734327369898 1.227219483528185 1.0 16.2493857527814 -5.970652943994881 24.784244812391087 1.1540853540895586 1.4911506864976987 0.4209237359723462 0.1895226490112787 186.54912341823916 157543.57518210716 0.052414257875386325 0.07774170917645619 1.0699095301961942e-06 5.970652943994881 0.3370653324081401 LLEEHAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLEEHAK 7 0 A0A2R8Y5M6;P51572;P51572-2 A0A2R8Y5M6 BCAP31 B-cell receptor-associated protein 31 0 ; 120.62 0.0050154 4788400.0 77753.0 71865.0 67469.0 65920.0 110820.0 72081.0 72258.0 52493.0 57883.0 59203.0 False True 90915.04720824941 78999.28226076084 69077.71683760724 62226.71611552359 89105.61652802613 68300.94546865157 65413.19913738293 51115.114370930925 58729.429371122555 69936.03524930989 1.2999742819871467 1.1295933774218403 0.9877270936414554 0.8897661397832475 1.2741016303023183 0.9766202105276699 0.935328960302027 0.7308837881460447 0.8397592051331231 1.0 16.09374838993609 -7.212120993479695 2.5457389896730396 0.8439888436761416 1.0974744100772231 0.4104908353893352 0.13223828176840036 0.2948757571914649 3.75865129680205 0.06152696106211272 0.04258966150448777 6.135910362479398e-08 7.212120993479695 0.25348556640108155 LLEEHAK ddPTM_PC-9_Lapatinib_30min_R1 2 LLEEHAK 7 0 A0A2R8Y5M6;P51572;P51572-2 A0A2R8Y5M6 BCAP31 B-cell receptor-associated protein 31 0 ; 108.09 0.0082348 5470500.0 185239.0 174465.0 92475.0 59357.0 76932.0 84531.0 95961.0 68446.0 128830.0 39654.0 False True 182597.45789132765 174061.03701159783 84872.06246382279 63722.31178914743 72407.01101413152 80915.80618138533 100929.3910392208 71626.25103440773 114319.80875995757 46508.14106436629 3.9261396760325598 3.7425928671434323 1.8248861494240682 1.370132418342782 1.5568674506667928 1.7398202622074177 2.170144596825245 1.5400798525849164 2.4580601620206957 1.0 15.505195655881188 -5.257938471024053 4.845407954414625 1.7190218549216212 3.8769870898714185 0.8335152922538102 0.38083975167591516 0.062474573385656165 4.4326890952851725 0.09614585787253523 0.24101340417418562 5.521556607808814e-06 5.257938471024053 2.1579652349497973 LLEELEEGQK ddPTM_PC-9_Lapatinib_30min_R1 2 LLEELEEGQK 10 0 E5RIF1;D6RG00;H0YBX6;I3L0A0;Q13404-8;Q15819;Q13404;Q13404-7;Q13404-2;Q13404-1 E5RIF1 UBE2V2;UBE2V1;TMEM189-UBE2V1 Ubiquitin-conjugating enzyme E2 variant 1;Ubiquitin-conjugating enzyme E2 variant 2 0 ; 114.97 0.0035486999999999997 4082200.0 16209.8 25404.1 27410.0 23715.7 22481.8 21605.1 26408.0 23599.5 20755.9 22625.2 False True 15978.64527948675 25345.278367273262 25156.45560565978 25459.831691256004 21159.464724919402 20681.100236947972 27775.27702466362 24696.018924210435 18418.151972683394 26535.93567381603 0.6021511913466634 0.9551303816387513 0.9480146437980164 0.9594472945748863 0.7973890570513484 0.7793620127499316 1.046704264212944 0.9306632043345994 0.6940833818367013 1.0 14.695659799532253 -1.522878877533731 0.018750416818360954 1.5750024864906813 1.914716838013172e-06 0.08076777786907918 0.13191281523705012 12325.882813355474 17.88698457162702 568.0009952427462 987.9743918414392 0.029999990864260626 1.522878877533731 -1.5750005717738433 LLEENETEAVTVPTPS(ph)PTPVR ddPTM_PC-9_AZD4547_30min_R2 6 LLEENETEAVTVPTPSPTPVR 21 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 LLEENETEAVTVPT(0.043)PS(0.932)PT(0.025)PVR;LLEENETEAVT(0.004)VPT(0.053)PS(0.668)PT(0.275)PVR;LLEENETEAVTVPT(0.001)PS(0.974)PT(0.025)PVR;LLEENETEAVTVPT(0.033)PS(0.655)PT(0.312)PVR;LLEENETEAVTVPT(0.002)PS(0.897)PT(0.101)PVR;LLEENETEAVTVPT(0.003)PS(0.89)PT(0.107)PVR 242.22 2.9292000000000002e-52 486267900.0 122229.0 132856.0 209312.0 296135.0 253594.0 235202.0 196484.0 288541.0 206716.0 228565.0 True False 161095.27947886253 175799.10385931874 206536.3861179685 227865.65099014164 218386.85045107306 220494.78175856743 213970.6953600565 243953.61846256198 217642.58574092176 220563.00891977162 0.7303821264854975 0.7970470874527493 0.9364053706444256 1.0331090970609051 0.9901336199603166 0.9996906681608202 0.9701114271518075 1.1060495577084666 0.9867592340476633 1.0 17.75083132827234 -5.269846132590059 1.9200010770495635 1.014273075396277 0.7280757593302308 0.8823453019205032 0.03616399095830675 0.11880868405133505 0.7804929673706973 0.010265480301350114 0.041803562972272196 5.372220965804623e-06 5.269846132590059 -0.28619731606604615 LLEENETEAVTVPTPS(ph)PTPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 LLEENETEAVTVPTPSPTPVR 21 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 LLEENETEAVTVPT(0.005)PS(0.897)PT(0.098)PVR;LLEENETEAVTVPT(0.197)PS(0.756)PT(0.046)PVR;LLEENETEAVTVPT(0.013)PS(0.955)PT(0.032)PVR;LLEENETEAVTVPT(0.003)PS(0.783)PT(0.214)PVR;LLEENETEAVTVPT(0.067)PS(0.83)PT(0.103)PVR;LLEENETEAVTVPT(0.189)PS(0.772)PT(0.039)PVR;LLEENETEAVTVPT(0.002)PS(0.876)PT(0.121)PVR 232.49 1.7993000000000002e-42 412880900.0 71302.04 88863.6 130107.7 139343.1 173058.6 138407.3 138111.7 138906.5 133344.6 111829.4 True False 83372.06709251726 97685.39092892704 133209.96100420013 131536.15786342547 139149.0096415547 131148.97753587362 125028.7599338828 135260.35155860276 135294.5125118013 132103.18497895676 0.6311132249067115 0.7394627990573257 1.0083781176465931 0.9957076953472271 1.053335766762325 0.9927768021396672 0.9464477329127161 1.0238992464878793 1.0241578394446196 1.0 17.011305724503416 -5.153828695188544 2.965320434743093 1.00689369257439 0.6430248271851442 0.9555886363740481 0.028019341251409945 0.051333338021281524 0.8393151495787917 0.007926158876085903 0.028490391004847782 7.017320377627006e-06 5.153828695188544 -0.3638688653892459 LLEENETEAVTVPTPS(ph)PTPVR ddPTM_PC-9_Lapatinib_30min_R1 5 LLEENETEAVTVPTPSPTPVR 21 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 LLEENETEAVTVPTPS(0.938)PT(0.061)PVR;LLEENETEAVTVPT(0.001)PS(0.754)PT(0.245)PVR;LLEENETEAVTVPT(0.03)PS(0.738)PT(0.233)PVR;LLEENETEAVTVPT(0.32)PS(0.675)PT(0.005)PVR;LLEENETEAVTVPT(0.026)PS(0.969)PT(0.005)PVR 235.85 3.141099999999999e-125 386620000.0 110186.5 89619.9 99858.1 83692.0 94224.20000000001 96272.2 77213.6 84712.09999999999 92880.40000000001 58748.9 True False 108615.22030427054 89412.39062778013 91648.1524814133 89846.98886832772 88682.11780790474 92154.86242745939 81211.34239895358 88648.13342272537 82419.23127802809 68903.5690870114 1.5763366360182485 1.2976452716820837 1.3300929646428046 1.3039526117271076 1.2870467957315388 1.3374468644880537 1.1786231609628222 1.2865535791154814 1.1961532961224275 1.0 16.07229109354973 -1.5228787478415806 0.03308306194504111 1.4392401572821052e-08 3.2110585998589447 0.7439607768539318 0.06980392179814088 582.0139855509752 1.4790923203668243 43.72551245203129 115.80119989907391 0.029999999823075597 1.5228787478415806 3.211058585466543 LLEENETEAVTVPTPSPT(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 1 LLEENETEAVTVPTPSPTPVR 21 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 LLEENETEAVTVPTPS(0.335)PT(0.665)PVR 208.89 2.1924e-24 52707000.0 20801.0 14810.0 18169.0 20075.0 18147.0 16422.0 12361.0 14002.0 23993.0 10256.0 True False 20504.37392556377 14775.708354923694 16675.214954368188 21551.382468236843 17079.62913837472 15719.669341551742 13000.992097162489 14652.584036814103 21290.655682509194 12028.735934739017 1.7046158496461037 1.2283675055374201 1.3862815714667183 1.7916581247740588 1.419902243347841 1.3068429988685095 1.080827791689698 1.218131657084383 1.7699827976954527 1.0 13.554197421356735 -6.675715790752717 4.005977026674181 1.2757275827966104 1.5067668942359178 0.19487095148929712 0.24007647138086619 0.4227011834543317 12.8684740608079 0.08328376821054477 0.08183251317264753 2.1100085215015688e-07 6.675715790752717 0.23103931143930745 LLEGEEER ddPTM_PC-9_AZD4547_30min_R2 3 LLEGEEER 8 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8;P20700;E9PBF6;Q03252 P02545;P02545-2;P20700;Q03252 LMNA;LMNB1;LMNB2 Prelamin-A/C;Lamin-A/C;Lamin-B1;Lamin-B2 0 ;; 148.04 0.0044831 53274000.0 107172.0 96527.0 150752.0 193820.0 150869.0 125486.0 116243.0 138269.0 121186.0 134696.0 False True 141250.4666839183 127727.465061634 148752.92998039295 149137.79348914928 129923.44353850218 117639.34058279921 126588.40180747042 116902.70315553054 127591.64455387766 129980.33403827179 1.0867064447020738 0.9826676166567286 1.1444264325139655 1.1473873689633443 0.9995623145594251 0.905054918139856 0.9739042659345479 0.8993876190617373 0.9816226854464707 1.0 16.987933835139117 -6.483662062522114 5.775410779833484 0.9472958131517873 1.0857881482608722 0.6143047781826236 0.05162492407915072 0.13534694854732654 12.193417366155858 0.016755984915872435 0.018531450697241058 3.283506931919026e-07 6.483662062522114 0.13849233510908487 LLEGEEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LLEGEEER 8 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8;P20700;E9PBF6;Q03252 P02545;P02545-2;P20700;Q03252 LMNA;LMNB1;LMNB2 Prelamin-A/C;Lamin-A/C;Lamin-B1;Lamin-B2 0 ;;; 157.34 0.00018115 72589000.0 213373.0 199240.0 219681.0 284170.0 308923.0 250522.0 244799.0 216900.0 205965.0 178719.0 False True 249492.83459115113 219019.23046871182 224919.0281848323 268248.87619157054 248391.7557723108 237384.1853012243 221609.8665287196 211206.6048245462 208976.8484775022 211119.33996117473 1.1817621002274512 1.0374190754337802 1.0653643963939796 1.2706030448982175 1.1765466670082927 1.1244075760414927 1.04969003109556 1.0004133437674991 0.9898517516961425 1.0 17.68769921981088 -7.405174250447113 2.318384041301204 0.9962896503052656 1.1432222495020214 0.551478399064295 0.060223360511407295 0.26939492477818927 2.82945845116334 0.03458241383436139 0.020276768126886315 3.933922044166616e-08 7.405174250447113 0.14693259919675583 LLEGEEER ddPTM_PC-9_Lapatinib_30min_R1 3 LLEGEEER 8 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8;P20700;E9PBF6;Q03252 P02545;P02545-2;P20700;Q03252 LMNA;LMNB1;LMNB2 Prelamin-A/C;Lamin-A/C;Lamin-B1;Lamin-B2 0 ;; 122.18 0.015388999999999998 65238000.0 125910.0 118272.0 145487.0 103101.0 134277.0 129220.0 114477.0 113351.0 121700.0 105083.0 False True 124114.50031093387 117998.14845060976 133525.62045606098 110683.39147485352 126379.09085873919 123693.56182653234 120404.05891973713 118617.70126816981 107992.86444218596 123246.45653570416 1.0070431540153713 0.9574161543251024 1.083403322166743 0.8980655070013217 1.02541764210582 1.0036277334326336 0.9769372873195459 0.9624430965591826 0.8762350454343548 1.0 16.911186642647657 -7.820997325093067 2.8999630623100714 0.9343404551887082 0.9941182000863461 0.14974389946073963 0.052764236685674135 0.44031108482788417 7.373812951781041 0.03178007513473726 0.013764467433185022 1.510089455079728e-08 7.820997325093067 0.059777744897637874 LLEPVLLLGK ddPTM_PC-9_Lapatinib_30min_R1 1 LLEPVLLLGK 10 0 M0R210;P62249;M0R3H0;M0R1M5;Q6IPX4;M0QX76 M0R210 RPS16 40S ribosomal protein S16 0 164.96 4.0891e-14 0.0 24692.0 21130.0 26283.0 25055.0 26596.0 27621.0 22883.0 21300.0 22310.0 24975.0 False True 24339.887552041786 21081.074783223325 24122.113195313967 26897.628281029847 25031.675569747815 26439.714217695815 24067.769772621094 22289.675759472953 19797.212865284877 29291.89547290433 0.8309427286655702 0.7196896767136084 0.8235081003080689 0.9182617869816846 0.8545597738085159 0.9026289965479753 0.8216528628160759 0.7609502696775431 0.6758597402342142 1.0 14.838213932305136 -5.504827176849844 23.937196486649647 0.8416654598854452 0.774386850505679 0.09539405725436967 0.08684294495227704 1080.8534424171894 1433255.7899941003 0.023365478281289986 0.04707913082605814 3.1273236067262393e-06 5.504827176849844 -0.06727860937976615 LLEQEALMEQQDPKS(ph)PSHK ddPTM_PC-9_AZD4547_30min_R2 1 LLEQEALMEQQDPKSPSHK 19 1 Q96PY5-3;Q96PY5;C9IZY8 Q96PY5-3 FMNL2 Formin-like protein 2 1 LLEQEALMEQQDPKS(0.5)PS(0.5)HK 59.9 0.0098977 7818800.0 37364.0 40302.0 38069.0 57339.0 41431.0 45358.0 56838.0 58194.0 44841.0 47208.0 True False 49244.97478052027 53328.8333514351 37564.1801861573 44120.37942871908 35679.020801116785 42521.7570896723 61896.471890204106 49201.45446508571 47211.20371528415 45555.262288996884 1.0809942102432935 1.1706404632932121 0.8245848733754366 0.9685023685919075 0.7832030595010856 0.9334104328039995 1.3587117882790496 1.0800388800959555 1.0363501677541045 1.0 15.475330095261452 LLES(ph)PGVEAGEGEAEKEEAGAQGR ddPTM_PC-9_Lapatinib_30min_R1 1 LLESPGVEAGEGEAEKEEAGAQGR 24 1 A0A0G2JHC2;Q6NYC8;Q6NYC8-3 A0A0G2JHC2 PPP1R18 Phostensin 1 LLES(1)PGVEAGEGEAEKEEAGAQGR 79.695 7.043199999999999e-05 1713900.0 1163.7 3734.1 4277.6 2386.5 5561.8 4341.8 4627.3 3551.5 4447.8 4555.9 True False 1147.1054246035558 3725.4539208724223 3925.9122400135075 2562.01117113062 5234.6658589195185 4156.111335230139 4866.878952447213 3716.515655388179 3946.841926589606 5343.381244644841 0.21467781767456506 0.6972090798510938 0.7347243365702332 0.4794737739700453 0.9796541963322798 0.777805502722721 0.910823826640635 0.695536306549881 0.7386412733594758 1.0 12.3835372402724 -4.691901065651035 2.3479368251782646 0.7793545319332437 3.8716633303530985e-34 0.5854466911161481 0.14402569831566853 0.6010692962452139 3.2168559942184483 0.03729599131620234 1.059230370519279 2.0328200442700567e-05 4.691901065651035 -0.7793545319332437 LLESQEPAHAQPAS(ph)PQNVLPVK ddPTM_PC-9_AZD4547_30min_R2 2 LLESQEPAHAQPASPQNVLPVK 22 0 F5H5T5;Q7Z3V4-2;Q7Z3V4 F5H5T5 UBE3B Ubiquitin-protein ligase E3B 1 LLESQEPAHAQPAS(1)PQNVLPVK;LLESQEPAHAQPAS(1)PQNVLPVK 86.131 0.00012737 2885700.0 19729.3 21033.2 20838.8 36058.0 31083.0 28028.0 27390.0 37068.0 30155.0 27052.0 True False 26002.807005066872 27831.77057335628 20562.463896169957 27745.385190546636 26767.66198163485 26275.40472925032 29827.656938539174 31339.992337900752 31748.931737347375 26104.917713987972 0.9960884493090593 1.066150480851468 0.7876854515098446 1.0628413195755695 1.0253877171691583 1.0065308390216068 1.1426068170502763 1.200539786459761 1.216205011070965 1.0 14.672033990684684 -7.245782678483618 3.2375177532349255 1.1600862237515197 0.9870249499357006 0.3843563736008515 0.09150179973775217 0.24613203273175938 5.356718511170888 0.039400899449626096 0.02750670071084489 5.67828676526674e-08 7.245782678483618 -0.17306127381581915 LLETTDRPDGHQNNLR ddPTM_PC-9_Lapatinib_30min_R1 2 LLETTDRPDGHQNNLR 16 1 Q14974;Q14974-2;J3KTM9 Q14974 KPNB1 Importin subunit beta-1 0 ; 68.033 0.010787 12517500.0 71419.0 75344.0 78406.0 75180.0 69863.0 71569.0 60433.0 65647.0 68471.0 58769.0 False True 70400.55196335938 75169.54559712148 71959.76133591244 80708.98799312799 65753.79569594268 68508.16070548762 63561.92503905997 68697.19927615607 60759.07494840522 68927.14334522985 1.0213763192063507 1.090565225090293 1.0439974419873077 1.170931857554104 0.9539608419082004 0.9939213694430407 0.9221610232808062 0.9966639547511482 0.8814970706690414 1.0 16.07278460425073 -6.293405022565798 24.51637171414416 0.9578679296143243 1.0796553738829586 0.5965237045178434 0.04982089055625292 347.30784656273147 266370.1761431975 0.014616888785302555 0.016575671499604875 5.088560910598049e-07 6.293405022565798 0.1217874442686343 LLEVEHPAAK ddPTM_PC-9_Lapatinib_30min_R1 1 LLEVEHPAAK 10 0 P17987;E7ERF2;F5H726;F5GZI8;F5H676;F5H136 P17987 TCP1 T-complex protein 1 subunit alpha 0 78.655 0.016868 6380300.0 62501.0 63218.0 63537.0 67535.0 69886.0 65130.0 66462.0 56978.0 61848.0 54256.0 False True 61609.724278720336 63071.62260510234 58313.23311991265 72501.74919015566 65775.44288116245 62344.5417254454 69903.07715893636 59625.40588841551 54882.026951687134 63634.07730842429 0.9681875951482374 0.9911611085268697 0.9163837300143074 1.1393541362869328 1.0336512394508262 0.9797351413342773 1.0985163942918073 0.9370043286621509 0.8624628386718431 1.0 15.957511943763423 -7.9702049577318865 23.217328190949065 0.920732126198044 1.0170277429847716 0.24487552580826433 0.06792171332870976 113.4287436443819 88387.16528596172 0.03700532925951706 0.017776158523621237 1.0710137396323358e-08 7.9702049577318865 0.0962956167867276 LLEVQPQVANS(ph)PSSAAQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLEVQPQVANSPSSAAQK 18 0 Q8NDI1-3;Q8NDI1-2;Q8NDI1;H7BZ98 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 LLEVQPQVANS(0.66)PS(0.246)S(0.094)AAQK 217.65 2.1534999999999996e-81 0.0 25409.0 23479.0 24364.0 28142.0 28382.0 26439.0 23332.0 21956.0 21260.0 17649.0 True False 29710.2418493744 25809.839952694685 24944.93016098455 26565.29497759501 22820.750841891764 25052.492296800534 21121.824050948246 21379.678264304956 21570.88728003153 20848.62399059288 1.4250456942760334 1.2379637123457334 1.1964784904864687 1.274198958625833 1.094592662431282 1.2016376864058023 1.013103985206824 1.0254719099904 1.0346432114543647 1.0 14.34766454847326 -1.5228787453514894 0.20805141455752674 0.9609892590943637 3.1048819229662006 0.8157190162496626 0.05707381349375903 21.182162233670407 0.2622167587058013 0.09793588940328152 14.982270565217904 0.029999999995085007 1.5228787453514894 2.1438926638718367 LLEVQPQVANS(ph)PSSAAQK ddPTM_PC-9_Lapatinib_30min_R1 2 LLEVQPQVANSPSSAAQK 18 0 Q8NDI1-3;Q8NDI1-2;Q8NDI1;H7BZ98 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 LLEVQPQVANS(0.522)PS(0.239)S(0.239)AAQK;LLEVQPQVANS(0.837)PS(0.081)S(0.081)AAQK 253.73 4.4161e-65 7514100.0 60858.0 51855.0 61848.0 52893.0 46250.0 41364.0 38940.0 35365.0 46682.0 29474.0 True False 59990.15376000965 51734.93293346171 56763.096180184104 56782.92766587554 43529.665930998555 39594.95814419352 40956.12266511667 37008.18700627987 41424.18157674712 34568.541628363666 1.7353972986464496 1.4965899773744846 1.6420448623614972 1.6426185482839362 1.2592277220998598 1.1454043554937143 1.1847801710996093 1.0705741481415132 1.1983201959193548 1.0 15.077172120265521 -6.381881816675889 2.988002814814715 1.1306199413064675 1.6238484816672314 0.9063179940162353 0.07745298954902742 0.07456941343718919 1.2753360330810553 0.02465950094574342 0.028503889935995983 4.150669782653857e-07 6.381881816675889 0.4932285403607639 LLGELLQDNAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLGELLQDNAK 11 0 P37837;F2Z393 P37837 TALDO1 Transaldolase 0 131.82 0.00064292 1695100.0 13275.0 11678.0 12036.0 16236.0 20016.0 17911.0 16118.0 16505.0 13587.0 11978.0 False True 15522.195306798587 12837.314662786688 12322.983886784194 15326.349557822217 16094.008486058261 16971.71562948653 14591.186355785341 16071.761238493033 13785.68417092137 14149.516582204169 1.0970124114572815 0.9072617137275322 0.8709120071482015 1.0831712496169763 1.1374246174812557 1.1994555100795343 1.0312144779657462 1.1358523201214146 0.9742865836320944 1.0 13.788465143817184 -5.842394480116979 8.984250897558072 1.0916239690351022 0.9535324693965972 0.29816823753179933 0.08431452165916233 0.310545792834355 31.22979837219893 0.02362688800938247 0.03514080449292625 1.4374922762856012e-06 5.842394480116979 -0.13809149963850498 LLGELLQDNAK ddPTM_PC-9_Lapatinib_30min_R1 2 LLGELLQDNAK 11 0 P37837;F2Z393 P37837 TALDO1 Transaldolase 0 ; 184.71 0.0039639 10113500.0 56878.0 49920.0 57141.0 52241.0 51210.0 46054.0 48786.0 43284.0 50189.0 44552.0 False True 56066.90928985226 49804.41330707565 52443.087550638615 56082.97741086726 48197.928482733754 44084.37777711751 51311.90036826866 45295.132656010675 44536.18630639996 52252.75383819154 1.0729943432928306 0.9531442775495137 1.0036425584962752 1.073301850932806 0.9223997768995266 0.8436756828861379 0.9819941840225996 0.866846803831121 0.8523222803589056 1.0 15.673219452035005 -6.390722563132982 6.145789284536602 0.9030230627055502 1.0185190283697545 0.4816297041503539 0.0579435810660482 0.20596897772831418 9.431635554600948 0.01763656550542703 0.019992619235014955 4.0670305705440777e-07 6.390722563132982 0.11549596566420428 LLGGLAVR ddPTM_PC-9_Lapatinib_30min_R1 1 LLGGLAVR 8 0 P23396;P23396-2;E9PL09;F2Z2S8;H0YCJ7;H0YF32 P23396 RPS3 40S ribosomal protein S3 0 90.939 0.041924 3220700.0 19510.0 21331.0 20925.0 23401.0 24698.0 21351.0 23609.0 23668.0 20130.0 23093.0 False True 19231.783822304184 21281.60938007273 19204.62727283585 25121.987603447575 23245.312198136242 20437.867501611923 24831.358500275812 24767.70168428196 17862.747421702592 27084.594280511705 0.7100635742637693 0.7857459173898564 0.7090609175805243 0.9275378963872354 0.8582484920168083 0.7545938214890547 0.9168074752422202 0.9144571791538031 0.6595168912888406 1.0 14.725184859360528 -14.522871575558396 0.02415943251785671 2.08353269573722 2.3801993202036815e-07 0.2652655777642 0.09358083573056294 3222.889739708123 5.860767354057927 362.43205806548247 174.5563691153481 3.000049527093409e-15 14.522871575558396 -2.083532457717288 LLGHS(ph)PVLR ddPTM_PC-9_AZD4547_30min_R2 2 LLGHSPVLR 9 0 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4 G8JLH2 CDC25B M-phase inducer phosphatase 2 1 LLGHS(1)PVLR;LLGHS(1)PVLR 73.9 0.016065 3238900.0 22314.2 21726.1 24811.0 39016.0 28481.0 24719.0 21856.0 34034.0 22132.0 23273.0 True False 29409.65143580678 28748.636947958268 24481.989928780582 30021.463991191064 24526.9047678455 23173.317022346884 23801.14165931772 28774.827323516653 23301.852336626504 22458.21935374989 1.309527303681634 1.2800942272014124 1.0901126907326595 1.3367695594342979 1.09211261950517 1.0318412451732328 1.059796472926675 1.2812604093971531 1.0375645535199456 1.0 14.454955924770005 -1.5228787452803394 0.22954374647708414 1.0488599000121126 2.535476550606169 0.4014540938543153 0.09743986970778214 57.43149376112935 0.7509632663275561 0.1459401055913266 32.05705070254245 0.029999999999999874 1.5228787452803394 1.4866166505940566 LLGHS(ph)PVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLGHSPVLR 9 0 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4 G8JLH2 CDC25B M-phase inducer phosphatase 2 1 LLGHS(1)PVLR;LLGHS(1)PVLR 82.494 0.0088934 5806400.0 28594.0 27304.0 28525.0 27785.0 33957.0 26036.0 31144.0 20941.3 19991.1 17568.6 True False 33434.399442756956 30014.560674150332 29205.144181664913 26228.296530185406 27303.369612364106 24670.626326241483 28193.814856966037 20391.61306414143 20283.432018054493 20753.648107038913 1.611013122623833 1.4462305865141099 1.407229419668128 1.2637921003049908 1.3155937438827323 1.1887368523837536 1.3584992244040064 0.9825555949956243 0.9773429670504561 1.0 14.34107733737423 -4.903080408698618 0.23239451625572494 0.9218624590892385 2.0809556741299775 0.8071453512198622 0.09017970308042454 4.713645741157976 0.23559133645665795 0.15825340583410605 1.5832254319887644 1.2500275688482963e-05 4.903080408698618 1.159093215040739 LLGHS(ph)PVLR ddPTM_PC-9_Lapatinib_30min_R1 2 LLGHSPVLR 9 0 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4 G8JLH2 CDC25B M-phase inducer phosphatase 2 1 LLGHS(1)PVLR;LLGHS(1)PVLR 77.387 0.01311 6894700.0 35538.0 31370.0 39612.0 32346.0 27445.0 25744.0 20403.7 20660.6 26372.0 18134.1 True False 35031.22160312895 31297.364692367064 36355.254266741875 34724.83274309284 25830.73905894605 24642.9891321951 21460.10374992915 21620.5669012285 23401.70765052858 21268.555022830602 1.6470898735492325 1.4715322530736619 1.7093429350379725 1.6326841530051137 1.2145037136381949 1.1586583623448905 1.0090061937396748 1.0165508130674619 1.1002960767860421 1.0 14.376434400050178 -6.430391958664478 2.3228388827790822 1.0518033043466561 1.616556548886515 0.9288603455604979 0.07305221540566174 0.07639930297693245 0.8123999554483791 0.02630017682342321 0.029998965819127726 3.712000630686506e-07 6.430391958664478 0.5647532445398589 LLGLTPPEGGAGDRS(ph)EEEASSTEKPTK ddPTM_PC-9_AZD4547_30min_R2 2 LLGLTPPEGGAGDRSEEEASSTEKPTK 27 2 V9GYY5;Q9UGY1 V9GYY5 NOL12 Nucleolar protein 12 1 LLGLT(0.001)PPEGGAGDRS(0.803)EEEAS(0.136)S(0.029)T(0.029)EKPT(0.002)K;LLGLT(0.004)PPEGGAGDRS(0.687)EEEAS(0.093)S(0.093)T(0.093)EKPT(0.029)K 55.468999999999994 0.011192 51296000.0 35728.0 32250.0 42489.0 46909.0 45231.0 41867.0 38191.0 35032.0 40822.0 43261.0 True False 47088.760811434186 42674.18181687711 41925.56809818058 36094.85478682545 38951.45639389137 39249.049871539966 41589.92501422968 29618.60935527517 42979.767580235246 41746.44555762358 1.1279705417419668 1.0222231197617282 1.0042907255495501 0.8646210307175229 0.9330484517568276 0.9401770461478834 0.9962506857457397 0.7094881722179658 1.0295431624450346 1.0 15.349365746125587 -4.9960389899741635 1.250756343264749 0.9170167817655235 1.1694039531094416 0.3362475325784 0.08725170495773482 1.0814322534077403 1.917160761197704 0.025786957622210463 0.31998632493681667 1.0091622817074493e-05 4.9960389899741635 0.2523871713439181 LLGLTPPEGGAGDRS(ph)EEEASSTEKPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLGLTPPEGGAGDRSEEEASSTEKPTK 27 2 V9GYY5;Q9UGY1 V9GYY5 NOL12 Nucleolar protein 12 1 LLGLT(0.002)PPEGGAGDRS(0.976)EEEAS(0.013)S(0.006)T(0.002)EKPT(0.001)K 55.631 0.0012514000000000002 25562000.0 30424.0 28034.0 35047.0 37678.0 37479.0 34475.0 37192.0 39204.0 33948.0 26394.0 True False 35574.18229860945 30817.03024974841 35882.653396487665 35567.02381372415 30135.258995252654 32667.070310231036 33668.904513237896 38174.936540071554 34444.425276693786 31179.023265210963 1.1409652571863125 0.988389853896852 1.1508588030890927 1.1407356642056599 0.9665235096981719 1.0477259031613224 1.0798575768986678 1.2243788464876806 1.1047307346258761 1.0 14.928288113470078 -7.550821221158673 24.99567308189981 1.1291565243277932 1.0699869582029757 0.025835554979618758 0.07796614548616015 508.7586019520425 455099.23017656454 0.03600548853093788 0.02078829711463025 2.8130585974864042e-08 7.550821221158673 -0.059169566124817496 LLGLTPPEGGAGDRS(ph)EEEASSTEKPTK ddPTM_PC-9_Lapatinib_30min_R1 1 LLGLTPPEGGAGDRSEEEASSTEKPTK 27 2 V9GYY5;Q9UGY1 V9GYY5 NOL12 Nucleolar protein 12 1 LLGLT(0.007)PPEGGAGDRS(0.769)EEEAS(0.154)S(0.033)T(0.033)EKPT(0.005)K 55.468999999999994 0.011192 10670000.0 35060.0 33258.0 30930.0 32341.0 30046.0 26461.0 25966.0 31284.0 31965.0 26580.0 True False 34560.037970783436 33180.993144365435 28387.054793252708 34719.465026413345 28278.753352708783 25329.324713603743 27310.392427386247 32737.5688478569 28364.765093627557 31174.31758437628 1.1086060786172265 1.064369510400922 0.9105910567703823 1.1137201297972854 0.9071169970656013 0.8125061485322813 0.8760542184594113 1.050145484636497 0.9098760547638485 1.0 14.92807035890153 -4.794873993097041 0.7709141730654037 0.9320268606120314 1.2183854941459613 0.30965115270785226 0.08331291748597264 3.45185866330907 1.5827439546427788 0.0348529657980078 0.8547674333456677 1.6037106263879856e-05 4.794873993097041 0.2863586335339299 LLGLTPPEGGAGDRSEEEAS(ph)STEKPTK ddPTM_PC-9_Lapatinib_30min_R1 1 LLGLTPPEGGAGDRSEEEASSTEKPTK 27 2 V9GYY5;Q9UGY1 V9GYY5 NOL12 Nucleolar protein 12 1 LLGLTPPEGGAGDRS(0.254)EEEAS(0.494)S(0.122)T(0.122)EKPT(0.008)K 85.06200000000001 2.5258e-06 10414000.0 55842.0 48183.0 51438.0 44632.0 49132.0 40727.0 36015.0 48662.0 59378.0 40065.0 True False 55045.68283983136 48071.435223854685 47208.966196422 47914.38616798738 46242.152357228544 38985.201149274 37879.68047725159 50923.01416936491 52690.224361940214 46990.18186674323 1.1714294487289336 1.0230101973254269 1.0046559583510275 1.0196680298847332 0.9840811531303287 0.8296456749163027 0.8061190438605326 1.0836947665743148 1.1213028396306575 1.0 15.520071730981622 -1.6637487613938469 0.8811732719874545 0.9679639442663635 68.06663748009045 0.2740032790682877 0.0928383176300447 871.0663490692679 2.78292748445397 0.03484034547040874 117077.90255415994 0.021689584806848662 1.6637487613938469 67.09867353582409 LLGMQQES(ph)RLWK ddPTM_PC-9_AZD4547_30min_R2 1 LLGMQQESRLWK 12 1 Q5YKI7-2;Q5YKI7 Q5YKI7-2 GGNBP1 Putative gametogenetin-binding protein 1 1 LLGMQQES(1)RLWK 62.042 0.025157 10724000.0 11777.0 8337.4 13308.0 23759.0 20923.0 14874.0 16211.0 14587.0 11165.0 14946.0 True False 15521.841023182398 11032.30150325678 13131.527224707264 18281.72962289082 18018.2026072691 13943.9264286738 17653.74759513175 12332.914325913418 11755.159106200746 14422.74508920834 1.076205738032245 0.7649238362752163 0.9104735016451747 1.2675624168501682 1.2492907900557033 0.9668011423919007 1.2240213278359175 0.8551017333823216 0.8150431165143739 1.0 13.816058159223758 -10.550523596928196 4.307232756449991 0.9999988053395926 1.0184248693370308 0.00012643768906206443 0.17538443155070693 2.1488736251524704e-06 4.853584113080323e-07 0.18136451010472152 0.04398450257292276 2.8149870616537283e-11 10.550523596928196 0.01842606399743818 LLGPAPEDDGGHNDHSQPQASQDQDS(ph)HTLSPQV ddPTM_PC-9_Lapatinib_30min_R1 1 LLGPAPEDDGGHNDHSQPQASQDQDSHTLSPQV 33 0 Q92610 Q92610 ZNF592 Zinc finger protein 592 1 LLGPAPEDDGGHNDHS(0.007)QPQAS(0.046)QDQDS(0.316)HT(0.316)LS(0.316)PQV 44.05 0.015412 2895200.0 6956.3 7774.6 11235.0 8241.0 8865.9 10914.0 8516.3 10582.0 10860.0 7465.6 True False 6857.101886370816 7756.598391370002 10311.301668354161 8847.0706311701 8344.425193030054 10447.233661776629 8957.232343424073 11073.67835149028 9636.832439130154 8756.019012713297 0.7831300818802073 0.8858590165356897 1.1776244036682277 1.0103987460882167 0.9529930418052279 1.1931488095911822 1.0229800015759016 1.264693273896717 1.1005951934478397 1.0 13.09605937183483 -5.091597533311922 4.239552686400334 1.0926977739539696 0.8016898061420892 0.5533936755893567 0.09370892767094559 0.15281549294577948 4.733346634487092 0.024276265896600573 0.07602342965105749 8.098460470432601e-06 5.091597533311922 -0.29100796781188043 LLGPAPEDDGGHNDHSQPQASQDQDSHTLS(ph)PQV ddPTM_PC-9_AZD4547_30min_R2 2 LLGPAPEDDGGHNDHSQPQASQDQDSHTLSPQV 33 0 Q92610 Q92610 ZNF592 Zinc finger protein 592 1 LLGPAPEDDGGHNDHS(0.002)QPQAS(0.063)QDQDS(0.178)HT(0.178)LS(0.578)PQV;LLGPAPEDDGGHNDHS(0.001)QPQAS(0.042)QDQDS(0.19)HT(0.166)LS(0.601)PQV 56.231 0.00060815 8265100.0 5995.38 6654.1 10953.8 16412.1 13204.9 13678.0 10295.400000000001 15759.2 7145.9 9550.8 True False 7901.786128349093 8804.907696982393 10808.545454914225 12628.543909417327 11371.627568165552 12822.71249774104 11211.670655167456 13323.97775038971 7523.617685356011 9216.429399037275 0.8573587217165135 0.9553491179460596 1.1727475996336778 1.370220869997276 1.2338430726061225 1.391288528622643 1.2164874453808108 1.4456767554451726 0.8163267312764213 1.0 13.169992219045412 -5.234095828244718 2.8608707426162603 1.2398279101663678 0.8760011261921012 0.30610488048994566 0.17930099774698918 0.28369204149673166 4.556476859791037 0.045638355348242995 0.14589044559924694 5.833163797455461e-06 5.234095828244718 -0.3638267839742666 LLGPAPEDDGGHNDHSQPQASQDQDSHTLS(ph)PQV ddPTM_PC-9_Lapatinib_30min_R1 1 LLGPAPEDDGGHNDHSQPQASQDQDSHTLSPQV 33 0 Q92610 Q92610 ZNF592 Zinc finger protein 592 1 LLGPAPEDDGGHNDHS(0.003)QPQAS(0.005)QDQDS(0.177)HT(0.177)LS(0.637)PQV 65.345 3.1855e-05 4343000.0 7712.4 8299.1 11191.0 8481.8 11252.0 9986.9 7247.8 11279.0 10552.0 9027.0 True False 7602.419761719059 8279.88394384518 10270.91917850924 9105.579866455353 10590.179482283145 9559.783567600962 7623.055620242235 11803.063516013865 9363.522642513937 10587.304922278581 0.7180694064758154 0.7820577573450296 0.9701164983825508 0.8600470028302223 1.0002715100798236 0.9029477886751487 0.7200185199352522 1.114831735050626 0.8844104057880233 1.0 13.370047766792487 -5.113684990672255 3.9779356598907105 0.9267663954868478 0.7295205145353 0.35503974097487245 0.09906117874956875 0.24431841028908552 6.531828681737284 0.025001814147607174 0.07910223752301665 7.696885204894471e-06 5.113684990672255 -0.19724588095154783 LLGPS(ph)LTSTTPASSSSGSSSR ddPTM_PC-9_AZD4547_30min_R2 1 LLGPSLTSTTPASSSSGSSSR 21 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6 A0A087WVP4 SMTN Smoothelin 1 LLGPS(0.292)LT(0.292)S(0.292)T(0.063)T(0.063)PASSSSGSSSR 91.845 0.00041076 2986500.0 6158.3 5412.7 8880.7 14274.0 11548.0 13672.0 9020.3 13542.0 9085.6 11201.0 True False 8116.511299402572 7162.249423882507 8762.936115453704 10983.349831101634 9944.759532989712 12817.08767868954 9823.089225363457 11449.395064202336 9565.846267379975 10808.856399319064 0.7509130475555116 0.6626278636039344 0.8107181547907095 1.0161435609222789 0.9200565874495485 1.1857949819276896 0.9088000490026209 1.0592605398036026 0.885000772883115 1.0 13.39992627040112 -5.617355235024776 3.260469146796756 1.000696698084492 0.7090751904622229 0.6672718895419174 0.0843444381510149 0.13030320300654014 2.7363965946861697 0.022493956132131305 0.043085709785870674 2.413485894643965e-06 5.617355235024776 -0.2916215076222691 LLGPSAAADILQLSS(ph)SLPLQSR ddPTM_PC-9_Lapatinib_30min_R1 1 LLGPSAAADILQLSSSLPLQSR 22 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 LLGPSAAADILQLS(0.007)S(0.678)S(0.315)LPLQSR 184.66 2.5419e-15 20162000.0 39281.0 28971.0 35065.0 27010.0 31381.0 27896.0 24771.0 24586.0 36517.0 32459.0 True False 38720.845736746836 28903.91942947293 32182.091054814282 28996.405502718644 29535.231277419796 26702.95310875211 26053.52117456612 25728.35531560573 32404.070918942525 38069.49490110119 1.0171095213461 0.7592409488111401 0.8453511437022871 0.7616703499231322 0.7758240910247922 0.70142651427665 0.6843673981556425 0.6758260224477398 0.8511820554258315 1.0 15.216347808170124 -4.760066650202332 24.995924168391948 0.7690353329057174 1.0171098228293443 0.35183380760148264 0.0930272629887353 35.55329033706709 647149.8748517003 0.02220018502362275 0.13493309888583 1.7375341528084068e-05 4.760066650202332 0.2480744899236269 LLGPSAAADILQLSSS(ph)LPLQSR ddPTM_PC-9_AZD4547_30min_R2 2 LLGPSAAADILQLSSSLPLQSR 22 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 LLGPSAAADILQLS(0.003)S(0.236)S(0.761)LPLQSR;LLGPSAAADILQLS(0.155)S(0.078)S(0.76)LPLQS(0.007)R 184.88 2.4755e-15 19343700.0 40242.0 40884.0 44206.0 51338.0 51889.0 48489.0 35172.0 55114.0 41955.0 36622.0 True False 53038.11891440146 54098.95346980478 43619.799556312726 39502.817264193334 44685.10801933692 45456.9751647145 38302.23986280763 46597.397693726765 44172.6556471699 35339.87492686925 1.500800979747556 1.53081904171293 1.2342941124318516 1.117797313825776 1.2644387709862097 1.2862800238761776 1.0838249977417456 1.3185501587131627 1.2499380866111953 1.0 15.109009313533354 -5.288860334572113 5.432933768927767 1.203511942811338 1.5178109613005286 0.6471239909045766 0.09487263201727693 0.09901779470219052 9.069144084522142 0.02386671511413839 0.05416752163645235 5.1420899025232e-06 5.288860334572113 0.3142990184891905 LLGPSAAADILQLSSS(ph)LPLQSR ddPTM_PC-9_Lapatinib_30min_R1 1 LLGPSAAADILQLSSSLPLQSR 22 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 LLGPSAAADILQLS(0.002)S(0.098)S(0.9)LPLQSR 134.58 2.4858e-05 17304000.0 58350.0 31994.0 44329.0 38767.0 37062.0 35838.0 32666.0 37388.0 42707.0 38219.0 True False 57517.91829992049 31919.919858705485 40684.44073488843 41618.05450292094 34882.08602669551 34305.292282458344 34357.28564403443 39125.18297160445 37896.887935352795 44825.1032263836 1.283163097459774 0.7120991935589731 0.9076262586483455 0.9284541809694031 0.7781819452936423 0.7653142951886521 0.766474211347986 0.8728408894901499 0.8454389439765321 1.0 15.452019284985994 -4.751566894133973 24.999995345449488 0.8358806737027513 1.2831639984245122 0.7126430758985403 0.08399868545332095 214.14371764458585 542236.7008713762 0.020482773758319424 0.2675882094932161 1.771875103192845e-05 4.751566894133973 0.4472833247217609 LLGPSETS(ph)SLR ddPTM_PC-9_AZD4547_30min_R2 1 LLGPSETSSLR 11 0 H7C3M7 H7C3M7 FARP2 1 LLGPS(0.013)ET(0.1)S(0.443)S(0.443)LR 67.87899999999999 0.038604 2820100.0 16340.0 22063.0 20720.0 22864.0 26366.0 26008.0 22302.0 29690.0 19742.0 22774.0 True False 21535.780106886345 29194.433284519688 20445.239261792507 17593.05804527866 22705.536010288073 24381.71564857791 24286.834795301253 25102.092708327233 20785.521815908203 21976.689191866113 0.979937420003057 1.3284272726268962 0.9303148023479161 0.8005326867793217 1.0331645413946937 1.109435340133123 1.1051179994978568 1.1422144841370316 0.9457985975249276 1.0 14.423686438891687 -6.535382266387308 23.06731151900686 1.0720906903287875 1.0131297654334095 0.026973642069239467 0.134580689037011 387.40688542999055 714701.0350583383 0.04725449919044125 0.04729928814063729 2.9148602219736396e-07 6.535382266387308 -0.058960924895377964 LLGPSETS(ph)SLR ddPTM_PC-9_Lapatinib_30min_R1 1 LLGPSETSSLR 11 0 H7C3M7 H7C3M7 FARP2 1 LLGPSET(0.022)S(0.559)S(0.419)LR 72.34 0.027478 1796000.0 25889.0 26226.0 23990.0 25081.0 26201.0 21633.0 18514.0 20278.0 20786.0 21164.0 True False 25519.818112538866 26165.275308320633 22017.63480407799 26925.540407763285 24659.908693147958 20707.807018986037 19472.564330302277 21220.189908478515 18444.861793716344 24822.16920074265 1.028105880116849 1.0541091351330325 0.8870149351580138 1.0847376065327 0.9934630810755316 0.834246469416802 0.7844827812115502 0.8548886173833523 0.7430801733945354 1.0 14.599341577145333 -6.746921694208878 5.39504620206352 0.829720512286955 1.0106707517328506 0.5234836508272781 0.07887067383488035 0.12838141991901364 10.989008376097154 0.02568296262611311 0.02448768504290894 1.7909287396701762e-07 6.746921694208878 0.1809502394458956 LLGPSLT(ph)STTPASSSSGSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLGPSLTSTTPASSSSGSSSR 21 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6 A0A087WVP4 SMTN Smoothelin 1 LLGPS(0.001)LT(0.274)S(0.274)T(0.222)T(0.222)PAS(0.007)S(0.001)SSGSSSR 108.49 0.00072059 0.0 5216.1 5816.6 11096.0 9322.5 7379.5 4005.9 6094.0 6462.5 4550.1 3881.4 True False 6099.082707328971 6394.0336074297875 11360.570721814336 8800.190548952794 5933.539949183996 3795.823552016086 5516.732203260694 6292.866222584747 4616.636604556512 4585.067094854506 1.330205770417959 1.394534360163531 2.477732710730339 1.919315544766754 1.294101007996761 0.827866522667873 1.203195523453022 1.3724698226655796 1.0068852884917288 1.0 12.162727130086697 -6.391601173685454 4.524157622849227 1.1087686998591257 1.7993218988662827 0.5089265652017431 0.3230875497022556 0.21001690646709614 6.789426186743974 0.1106910663587504 0.12569820929789813 4.0588109776245463e-07 6.391601173685454 0.690553199007157 LLGPSLTS(ph)TTPASSSSGSSSR ddPTM_PC-9_AZD4547_30min_R2 1 LLGPSLTSTTPASSSSGSSSR 21 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6 A0A087WVP4 SMTN Smoothelin 1 LLGPSLT(0.032)S(0.321)T(0.321)T(0.321)PAS(0.005)S(0.001)SSGSSSR 157.88 1.0202999999999999e-05 3176500.0 14310.0 13780.0 16347.0 23473.0 23005.0 19524.0 14629.0 26127.0 18873.0 21971.0 True False 18860.282333509393 18234.115517412913 16130.22809905995 18061.662504234875 19811.152845205088 18303.16119358794 15930.952659871851 22089.672488732434 19870.58825000685 21201.801977451934 0.8895603474443945 0.8600266872035146 0.7607951492148832 0.8518928024817612 0.9344089179907539 0.863283281914118 0.7513961632513303 1.0418771249832797 0.9372122365419304 1.0 14.371899266670656 -7.772577567557319 24.999292050191006 0.9921585275314444 0.8463267982133081 0.591285530389994 0.05658077944644798 163.23375069641847 366366.91847858543 0.03135019123639763 0.015280197494775676 1.6881943110920877e-08 7.772577567557319 -0.14583172931813626 LLGPSLTSTT(ph)PASSSSGSSSR ddPTM_PC-9_Lapatinib_30min_R1 1 LLGPSLTSTTPASSSSGSSSR 21 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6 A0A087WVP4 SMTN Smoothelin 1 LLGPSLT(0.001)S(0.002)T(0.044)T(0.862)PAS(0.031)S(0.044)S(0.014)S(0.001)GSSS(0.001)R 142.84 6.7034e-11 0.0 14144.0 11744.0 17832.0 10897.0 8606.0 8089.0 7337.7 6629.4 8689.4 7305.2 True False 13942.30396630807 11716.807489549214 16365.92179351059 11698.40173132637 8099.8120000469935 7743.0523263799805 7717.610202358158 6937.426125814558 7710.708268561468 8567.894086432862 1.6272731461965095 1.3675247816266323 1.9101452035250757 1.3653765573328718 0.9453678953469944 0.9037287632489521 0.9007592909649623 0.8097002665800775 0.8999537331782923 1.0 13.064724930725687 -6.157234124596647 3.1648085803990353 0.8948827489079403 1.6122466495823506 0.8595720146454748 0.13299233974891692 0.0863716095808607 1.6505488569490714 0.039947743088328096 0.05326763771777742 6.962510696736729e-07 6.157234124596647 0.7173639006744104 LLGPVLVK ddPTM_PC-9_Lapatinib_30min_R1 1 LLGPVLVK 8 0 O15212;A2AB88 O15212 PFDN6 Prefoldin subunit 6 0 117.7 0.0048673 0.0 12008.0 12500.0 14390.0 13178.0 13386.0 13367.0 12730.0 12477.0 13320.0 12856.0 False True 11836.763718002501 12471.057017997715 13206.909747006348 14147.1540805193 12598.661797888573 12795.324569998913 13389.097111631629 13056.726969527885 11819.761334181741 15078.142470456785 0.7850279794871783 0.8270950511598336 0.87589766265196 0.9382557638143022 0.8355579490360726 0.8486008535248496 0.887980541228167 0.8659373656344247 0.7839003615558533 1.0 13.880171088413087 -12.067263942270861 2.357762852626134 3.811588033584197 0.8536495817572047 0.5069733561551224 0.0442883815057005 1534579.8095823824 549065.3207786148 22523781.74128193 0.011436385506235477 8.565171391211052e-13 12.067263942270861 -2.957938451826992 LLGSENDT(ph)GSPDFYTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLGSENDTGSPDFYTPR 17 0 Q9P2Q2 Q9P2Q2 FRMD4A FERM domain-containing protein 4A 1 LLGS(0.001)ENDT(0.599)GS(0.4)PDFYTPR 100.77 0.0057589 0.0 1603.9 3426.6 3596.3 1909.6 7405.4 5506.7 5181.7 3705.6 4951.0 1548.7 True False 1875.4085915310172 3766.770202389526 3682.049431043701 1802.6113030067302 5954.365030108704 5217.918958008682 4690.85186374072 3608.331926407743 5023.3990086282265 1829.4670504975466 1.0251119805743296 2.0589439975784782 2.0126350075790223 0.9853204530338425 3.254699246148948 2.8521524651617005 2.564053756783968 1.9723404832169085 2.745826445609966 1.0 10.837207717003826 -6.254747488342158 24.997873357515097 2.4777881975517166 1.5941152728270171 0.29151759038786285 0.6593923038912827 686.7283112711435 2565304.059966703 0.19082607676166435 0.24072435356402566 5.562275704315679e-07 6.254747488342158 -0.8836729247246995 LLGSLDEVVLLS(ph)PVPELR ddPTM_PC-9_AZD4547_30min_R2 2 LLGSLDEVVLLSPVPELR 18 0 Q9H1A4;H0Y564 Q9H1A4 ANAPC1 Anaphase-promoting complex subunit 1 1 LLGSLDEVVLLS(1)PVPELR;LLGSLDEVVLLS(1)PVPELR 122.5 5.7061e-05 3822600.0 8050.900000000001 7136.200000000001 9769.599999999999 13623.0 9163.2 9070.3 7946.5 11243.5 8957.6 9225.9 True False 10610.918730877063 9442.837094003055 9640.048720656758 10482.427823251895 7891.047848345283 8503.132707139966 8653.72310558969 9506.075424926814 9431.080448697154 8902.904049145403 1.1918491620602845 1.0606468453301459 1.0827982271225436 1.1774166907098265 0.8863453772820061 0.9550965235839185 0.9720112738292813 1.067749958041984 1.0593263048367292 1.0 13.120060291967139 -6.248147399165306 24.993778012778037 0.9908222997906181 1.120112703049049 0.5542173191798637 0.06049706149099286 689.4644294046789 1296444.8421423577 0.01911278418047524 0.02452297517545984 5.64745268234133e-07 6.248147399165306 0.12929040325843089 LLHEDLDES(ph)DDDMDEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLHEDLDESDDDMDEK 16 0 O43150;O43150-2 O43150 ASAP2 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 1 LLHEDLDES(1)DDDMDEK;LLHEDLDES(1)DDDMDEK 103.71 0.0024294 1386800.0 14307.400000000001 15744.800000000001 13356.900000000001 18193.1 17661.7 13497.7 18527.9 16372.599999999999 16657.3 14467.2 True False 16729.36023596912 17307.83969024182 13675.379152325342 17173.799589826016 14201.01667057429 12789.856850657168 16772.80318162025 15942.836598203636 16900.881499984436 17089.988837707817 0.9788982541086865 1.0127472788076568 0.8001982495244007 1.0049040846611483 0.830955292331191 0.748382984454459 0.9814402654618638 0.9328757759646353 0.9889346131516407 1.0 14.060863834270416 LLHEDLDES(ph)DDDMDEK ddPTM_PC-9_Lapatinib_30min_R1 1 LLHEDLDESDDDMDEK 16 0 O43150;O43150-2 O43150 ASAP2 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 1 LLHEDLDES(1)DDDMDEK 112.55 0.00023181 1643800.0 15718.0 26358.0 20331.0 22743.0 24181.0 25577.0 22583.0 21391.0 23705.0 21865.0 True False 15493.858437671819 26296.969670430695 18659.463659929537 24415.596088423943 22758.721121675135 24483.1313328991 23752.237240532355 22384.903951684795 21035.093275283634 25644.336116718834 0.6041824739448253 1.0254494228566275 0.7276251401089886 0.952085325090798 0.8874755430629994 0.9547188596135001 0.9262176697585505 0.8728985554471402 0.8202627348020836 1.0 14.646352602706562 -4.745794689377058 24.91612716853338 0.9006631437809122 0.6041816236009611 0.5440510449211007 0.08307220796126456 641.1201935346279 1021005.8801746109 0.0193443954560305 0.46998740719146825 1.7955822790859987e-05 4.745794689377058 -0.2964815201799511 LLHGAGGHLES(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 2 LLHGAGGHLESPAR 14 0 H7C3A6;H7C2E6;H7C361;Q6NZ36-5;Q6NZ36;Q6NZ36-4;Q6NZ36-3;Q6NZ36-2 H7C3A6 C1orf86;FAAP20 Fanconi anemia-associated protein of 20 kDa 1 LLHGAGGHLES(1)PAR;LLHGAGGHLES(1)PAR 99.39200000000001 0.0012564 8574800.0 34307.0 31771.0 34340.0 43239.0 50379.0 32707.0 31388.0 29540.0 32302.0 33737.0 True False 45215.91237007033 42040.354434232664 33884.629162642595 33270.91658589065 43384.74545483966 30661.82611958004 34181.47119338695 24975.27176167013 34009.417774160014 32555.87789874362 1.3888709286446634 1.291329159207071 1.0408144811217102 1.0219634282132082 1.332624037655392 0.9418215111552353 1.0499324054384067 0.7671509224647253 1.044647540451443 1.0 14.990630422166083 -1.5228787452803376 0.32784484515072393 0.9433287671800049 5.5821377604801885 0.5071768346014836 0.12823602312430957 47.86389728931925 0.681863886319163 0.11991387568472846 134.23007615913983 0.029999999999999995 1.5228787452803376 4.6388089933001835 LLHGAGGHLES(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 2 LLHGAGGHLESPAR 14 0 H7C3A6;H7C2E6;H7C361;Q6NZ36-5;Q6NZ36;Q6NZ36-4;Q6NZ36-3;Q6NZ36-2 H7C3A6 C1orf86;FAAP20 Fanconi anemia-associated protein of 20 kDa 1 LLHGAGGHLES(1)PAR;LLHGAGGHLES(1)PAR 114.96 9.4015e-05 7690000.0 39152.0 41300.0 35103.0 40835.0 38612.0 40149.0 27421.0 30194.0 40345.0 32010.0 True False 38593.68530040251 41204.37238746443 32216.96684149853 43838.1421215667 36340.91807411278 38431.9208618902 28840.72520801655 31596.923468616245 35800.921248315484 37542.885849356055 1.0279893094863 1.0975281056656216 0.8581377300288472 1.167681735961132 0.9679841400560876 1.023680518756642 0.7682074660893772 0.8416221277022103 0.9536006739590998 1.0 15.196251931170936 -7.224827482794799 23.05459560921208 0.8776594323609901 1.0236517379340282 0.31510266142740595 0.09525106452356447 247.92884955520066 156121.13536175262 0.03499926485658358 0.027108756044436178 5.9589880870801805e-08 7.224827482794799 0.1459923055730381 LLHIEELR ddPTM_PC-9_AZD4547_30min_R2 1 LLHIEELR 8 0 Q9Y224 Q9Y224 C14orf166 UPF0568 protein C14orf166 0 161.9 2.0349e-05 2907500.0 9905.9 9459.0 11582.0 15582.0 13246.0 13925.0 11990.0 13693.0 10217.0 9663.3 False True 13055.770144480135 12516.436769173359 11428.41511245563 11989.810639500185 11407.021542603188 13054.267548694543 13057.086772292265 11577.06148383715 10757.049761581104 9324.990808279605 1.4000839692933524 1.342246553000362 1.225568512336592 1.285771845357156 1.2232742934690037 1.3999228328572437 1.4002251627635873 1.2415091576881712 1.1535721570931718 1.0 13.186886587954255 -8.434269127123597 1.862542197317036 1.0048733832101577 1.3187272515515325 0.7145845539253856 0.06490025930738327 0.18869340445689087 1.4030152578235275 0.06636010960435623 0.01895318449372446 3.6790091916584756e-09 8.434269127123597 0.31385386834137474 LLHIEELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLHIEELR 8 0 Q9Y224 Q9Y224 C14orf166 UPF0568 protein C14orf166 0 ; 139.97 0.0021833 3820500.0 21930.0 24014.0 24106.0 27735.0 29780.0 26667.0 30440.0 30552.0 23661.0 22748.0 False True 25642.31586275655 26397.95121700286 24680.77846251409 26181.097868083194 23944.82277751872 25268.53557542947 27556.50283348466 29750.042372519787 24006.997362785794 26872.032326931087 0.95423805504498 0.9823578245158219 0.9184559679834514 0.9742879715816865 0.8910685461449551 0.9403284153579037 1.0254714827009046 1.1071005724678429 0.8933822745786905 1.0 14.71381781579103 -7.2578723632987465 24.593278280138627 1.0154136322917537 0.9431082085814793 0.23744709867621405 0.05440317862191874 313.34315050501647 2160397.548117767 0.02071184210348495 0.015361631206021804 5.522397155744269e-08 7.2578723632987465 -0.07230542371027449 LLHIEELR ddPTM_PC-9_Lapatinib_30min_R1 3 LLHIEELR 8 0 Q9Y224 Q9Y224 C14orf166 UPF0568 protein C14orf166 0 ;; 182.68 2.9603e-32 1674800.0 37543.0 36382.9 37901.9 38474.5 42397.0 45798.0 35419.0 34510.1 43155.0 31982.6 False True 37007.629935457 36298.65763040871 34785.752087565 41304.04307716953 39903.29181570905 43839.32630035239 37252.822513502004 36113.56523131399 38294.429457703656 37510.749795864256 0.9865873152857444 0.9676868051944622 0.9273542191737341 1.1011254987423233 1.0637828364632846 1.1687136764508474 0.9931239102453054 0.9627524223814818 1.0208921353506457 1.0 15.195016480617713 -5.752899988774443 24.999660952273867 1.0466476804557932 0.9612571793915835 0.3100028067388563 0.05721581878152409 249.45649426816948 730293.6171725936 0.017044369390826736 0.02893450352765276 1.766444558401184e-06 5.752899988774443 -0.08539050106420965 LLHPS(ph)PDLVSQEATLSEAR ddPTM_PC-9_AZD4547_30min_R2 3 LLHPSPDLVSQEATLSEAR 19 0 A0A087WU05;A0A087WY48;Q8IY22-3;Q8IY22-2;Q8IY22 A0A087WU05 CMIP C-Maf-inducing protein 1 LLHPS(1)PDLVSQEATLSEAR;LLHPS(0.999)PDLVS(0.001)QEATLSEAR;LLHPS(1)PDLVSQEATLSEAR 153.72 1.2420999999999998e-05 12073900.0 31526.7 26852.399999999998 44308.0 59014.0 59555.0 51092.0 43020.0 50983.0 47301.0 51720.0 True False 41551.534803902876 35531.913172698034 43720.44696966711 45409.23405721112 51286.81624412903 47897.20916322454 46848.696659217094 43104.7488227904 49801.23429309459 49909.2985423428 0.8325409496318759 0.7119297247296099 0.8759980253494225 0.9098351486283893 1.0276004220058823 0.9596850799774072 0.9386767201200171 0.8636616839289085 0.9978347872559953 1.0 15.607021006959382 -5.584101817633527 2.503686104978199 0.9550892626863909 0.7728946471564364 0.6616190309293044 0.05249526570785742 0.16675382384518472 2.095503252529916 0.014956418470754311 0.03221447362427328 2.6055426251646e-06 5.584101817633527 -0.18219461552995453 LLHPS(ph)PDLVSQEATLSEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LLHPSPDLVSQEATLSEAR 19 0 A0A087WU05;A0A087WY48;Q8IY22-3;Q8IY22-2;Q8IY22 A0A087WU05 CMIP C-Maf-inducing protein 1 LLHPS(0.999)PDLVSQEATLSEAR;LLHPS(1)PDLVSQEATLSEAR;LLHPS(1)PDLVSQEATLSEAR;LLHPS(1)PDLVSQEATLSEAR 163.91 6.1959e-08 11301900.0 63607.4 63040.3 76159.3 82750.5 98558.0 86987.0 86112.2 102109.0 85788.0 67423.1 True False 74374.87651658461 69298.52436517135 77975.22654775361 78114.25776574064 79246.26740452297 82425.24858813832 77955.02901766109 99428.74694342862 87042.487205049 79646.37430903397 0.9338137129507547 0.8700775768685693 0.9790179053876806 0.9807635117532331 0.9949764580248366 1.034890154174779 0.9787643153119521 1.2483775665372732 1.0928618905779381 1.0 16.281321067911044 -6.635156363259353 0.7578257867946064 1.109278449184196 0.9138415592174277 0.4526465378571767 0.07126627695864099 0.5718091859533736 0.7293538578276764 0.04783280310723999 0.05380219029917113 2.3165604460528484e-07 6.635156363259353 -0.19543688996676833 LLHPS(ph)PDLVSQEATLSEAR ddPTM_PC-9_Lapatinib_30min_R1 3 LLHPSPDLVSQEATLSEAR 19 0 A0A087WU05;A0A087WY48;Q8IY22-3;Q8IY22-2;Q8IY22 A0A087WU05 CMIP C-Maf-inducing protein 1 LLHPS(1)PDLVSQEATLSEAR;LLHPS(1)PDLVSQEATLSEAR;LLHPS(1)PDLVSQEATLSEAR 168.17 3.7791000000000004e-08 13300700.0 65168.0 64151.0 77276.0 70850.0 82681.0 74377.0 71552.0 69607.0 90065.0 68641.0 True False 64238.692369652446 64002.46230092573 70922.66557398642 76060.54534867138 77817.86613710028 71196.06909125531 75256.61245337519 72841.19533284666 79920.93127350447 80505.50539161675 0.7979416073120111 0.7950072729757742 0.8809666522678806 0.9447868810794617 0.9666154601298069 0.8843627369944955 0.9348008199848138 0.9047976902761212 0.992738706312461 1.0 16.296799825256194 -5.447605363813232 2.5349995348126555 0.940643691336251 0.7936056398876147 0.7547015093972927 0.03405666909038462 0.13920713091472317 1.730824287650988 0.009366044960249821 0.023450811376612982 3.5677518186080704e-06 5.447605363813232 -0.14703805144863635 LLHPSPDLVSQEAT(ph)LSEAR ddPTM_PC-9_AZD4547_30min_R2 1 LLHPSPDLVSQEATLSEAR 19 0 A0A087WU05;A0A087WY48;Q8IY22-3;Q8IY22-2;Q8IY22 A0A087WU05 CMIP C-Maf-inducing protein 1 LLHPS(0.418)PDLVS(0.012)QEAT(0.553)LS(0.017)EAR 89.50200000000001 0.0025745 2826000.0 6959.9 5459.4 7867.6 11823.0 10108.0 8708.6 6967.1 8459.0 8549.4 9801.2 True False 9173.003425086796 7224.044285614233 7763.27048340148 9097.39001352911 8704.678676780397 8164.049865318585 7587.1584029389005 7151.855918482316 9001.303830053972 9458.062971253097 0.9698606842613848 0.7637974400858869 0.8208097690824452 0.9618660862356045 0.9203447580373971 0.8631841308450213 0.8021894573972876 0.7561649716458557 0.9517069041951399 1.0 13.207329031872494 LLHQFSFS(ph)PER ddPTM_PC-9_AZD4547_30min_R2 2 LLHQFSFSPER 11 0 Q9UJX6-2;Q9UJX6 Q9UJX6-2 ANAPC2 Anaphase-promoting complex subunit 2 1 LLHQFS(0.368)FS(0.632)PER;LLHQFSFS(1)PER 84.352 0.012055 11245200.0 41963.0 47815.0 54701.0 74095.0 64790.0 65361.0 56450.0 69465.0 60425.0 60923.0 True False 55306.36111537764 63270.26367671252 53975.62899900155 57013.54250633846 55795.026856806646 61273.96633753852 61473.94064185974 58730.78039689972 63618.94213991758 58790.10431351799 0.9407426940499692 1.076206011462449 0.9181073860859026 0.9697812781942787 0.9490547347774876 1.0422496617929864 1.0456511577871896 0.9989909200313387 1.0821369154347504 1.0 15.843285717276572 -6.7713139057892535 24.992292081753707 1.0344830134706378 0.973653943200597 0.3285112677056794 0.044955899337160134 253.87302915167118 642545.3454884697 0.015340431232093365 0.013688085163669494 1.693113584392864e-07 6.7713139057892535 -0.06082907027004081 LLHQFSFS(ph)PER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLHQFSFSPER 11 0 Q9UJX6-2;Q9UJX6 Q9UJX6-2 ANAPC2 Anaphase-promoting complex subunit 2 1 LLHQFS(0.009)FS(0.991)PER;LLHQFS(0.213)FS(0.787)PER 106.55 0.0013714999999999999 9363600.0 47492.0 55909.0 65074.0 67377.0 73926.0 68108.0 59555.0 57916.0 52682.0 50535.0 True False 55531.4575902432 61459.27603029125 66625.6109545192 63602.08512918121 59440.73098223135 64536.29658271844 53913.519259138615 56395.76636707442 53452.37458544784 59696.595465160084 0.9302282174978014 1.029527321472795 1.11607053024327 1.065422318200716 0.9957139183409871 1.0810716436983896 0.9031255273276586 0.9447065771110501 0.8954007204086458 1.0 15.865361035569073 -7.26593052725125 24.98785771141676 0.9312004180702309 1.0391289067297482 0.4524652593338213 0.054030160902240505 348.42502215519187 1938557.9668610035 0.022373549324304118 0.015662794701214608 5.420875995474488e-08 7.26593052725125 0.10792848865951732 LLHS(ph)PMTK ddPTM_PC-9_AZD4547_30min_R2 1 LLHSPMTK 8 0 A0A6I8PS19;A0A6I8PL80;Q9NVN8 A0A6I8PS19 GNL3L Guanine nucleotide-binding protein-like 3-like protein 1 LLHS(0.998)PMT(0.002)K 63.623999999999995 0.032466 8430000.0 31205.0 27427.0 38797.0 48601.0 48175.0 38740.0 31183.0 42354.0 32354.0 39854.0 True False 41127.540895678576 36292.24138578261 38282.52643049052 37396.790327964874 41486.732811030386 36317.58167586546 33958.22659052458 35809.16249809673 34064.1663879999 38458.72359061348 1.0693943286697238 0.9436673398760526 0.9954185385350136 0.9723877143206128 1.078734002008219 0.9443262356405764 0.8829785135878164 0.9311063695009519 0.8857331499247638 1.0 15.231023261310721 -6.984883048243232 24.76176378127471 0.918418936745506 1.0056670012850202 0.42151641641532467 0.048577035603395116 197.0744139709361 322809.044725666 0.01631022990097848 0.01437925589401396 1.0354209590698569e-07 6.984883048243232 0.08724806453951417 LLHS(ph)PMTK ddPTM_PC-9_Lapatinib_30min_R1 1 LLHSPMTK 8 0 A0A6I8PS19;A0A6I8PL80;Q9NVN8 A0A6I8PS19 GNL3L Guanine nucleotide-binding protein-like 3-like protein 1 LLHS(0.969)PMT(0.031)K 58.592 0.043669 7093000.0 34653.0 23691.0 31470.0 23959.0 28775.0 24859.0 20807.0 20786.0 29309.0 21622.0 True False 34158.84186541809 23636.1449450707 28882.65807771298 25721.02478488101 27082.511073826663 23795.83851915935 21884.28465056709 21751.79344302371 26007.911782547497 25359.33389049599 1.3469928671202176 0.9320491242843293 1.1389359910804848 1.0142626338667584 1.0679504118984953 0.9383463549126346 0.8629676451702363 0.8577430912400941 1.0255755097847652 1.0 14.63022923048816 -1.5228787452803376 0.5986680607706826 0.9487065048466689 21.106013621379358 0.5356048814390617 0.09373542797326906 141.131247658817 1.0985810006803667 0.04319758090799212 3719.8064054676884 0.029999999999999995 1.5228787452803376 20.15730711653269 LLIDGDGAGDDRR ddPTM_PC-9_Lapatinib_30min_R1 2 LLIDGDGAGDDRR 13 1 H7C5E3;Q6I9Y2 H7C5E3 THOC7 THO complex subunit 7 homolog 0 ; 101.39 0.0012741 2066600.0 28534.0 24063.0 25499.9 22418.2 25745.7 29357.0 23504.0 22601.0 28697.0 21274.2 False True 28127.099927505245 24007.283601926312 23403.396654460546 24066.90921292291 24231.388543993708 28101.469544509455 24720.92211404476 23651.12496900697 25464.841667193195 24951.417123910367 1.1272746468797437 0.9621611262680823 0.9379586152657282 0.9645507945863382 0.9711427781299575 1.126247435364321 0.9907622477424447 0.9478870419084391 1.0205769692652376 1.0 14.606834135776447 -4.754065958915892 24.984235906408085 0.9907003091120081 1.127274889276108 0.39176791928125887 0.05084050859056308 295.305309942283 1000533.289384512 0.013458413312948551 0.1360058713672518 1.7617084648286875e-05 4.754065958915892 0.13657458016409985 LLIDPNCSGHS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 LLIDPNCSGHSPR 13 0 Q8WYQ5-3;Q8WYQ5;C9JSD5;Q8WYQ5-2 Q8WYQ5-3 DGCR8 Microprocessor complex subunit DGCR8 1 LLIDPNCS(0.061)GHS(0.939)PR;LLIDPNCS(0.003)GHS(0.997)PR 152.68 7.9942e-05 9350000.0 47290.0 51482.0 133730.0 169893.0 138632.0 117064.0 72254.0 130059.0 88534.0 109765.0 True False 62327.236306894374 68122.54971461913 131956.65282237026 130726.79367068454 119385.33976250688 109743.96957417412 78684.46602545482 109961.37000849898 93213.72649425671 105922.16075986583 0.5884248948451429 0.6431378403340781 1.2457889064548706 1.234177935314715 1.1271044595961668 1.0360812958014767 0.7428517834321651 1.0381337504791879 0.8800210062328678 1.0 16.692644932262432 -5.17875971739533 7.2946253308265465 1.0385864177047541 0.6083035318343832 0.5829981694348699 0.14292575912144084 0.20768168022731895 15.938053224247676 0.04034833742517274 0.10842724953125236 6.625829903579851e-06 5.17875971739533 -0.4302828858703709 LLIDPNCSGHS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLIDPNCSGHSPR 13 0 Q8WYQ5-3;Q8WYQ5;C9JSD5;Q8WYQ5-2 Q8WYQ5-3 DGCR8 Microprocessor complex subunit DGCR8 1 LLIDPNCS(0.008)GHS(0.992)PR;LLIDPNCSGHS(1)PR 150.01 3.4573999999999996e-08 0.0 28432.0 48006.0 60080.0 60648.0 78026.0 65879.0 57288.0 56601.0 57530.0 37048.0 True False 33244.97604240282 52771.71841939871 61512.53505466881 57250.08918346895 62737.36541432755 62424.189266648646 51861.26591079731 55115.2837237167 58371.26741393288 43764.50912819337 0.7596332440293772 1.205810814987591 1.4055346736436272 1.3081396392628126 1.4335215146720734 1.426365575900738 1.1850073711300455 1.259360262953597 1.3337580742184023 1.0 15.417473768542491 -4.778478357163252 3.431152060391812 1.3097462211756499 0.6881656686347896 0.621975952884573 0.12377188036887464 0.18403509088434156 3.49431279642304 0.030178355735158948 0.30336193071719314 1.6654118206379076e-05 4.778478357163252 -0.6215805525408603 LLIDPNCSGHS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 LLIDPNCSGHSPR 13 0 Q8WYQ5-3;Q8WYQ5;C9JSD5;Q8WYQ5-2 Q8WYQ5-3 DGCR8 Microprocessor complex subunit DGCR8 1 LLIDPNCSGHS(1)PR;LLIDPNCS(0.087)GHS(0.913)PR 127.49 6.598300000000001e-05 11121600.0 79881.0 68260.0 111633.0 76205.0 92626.0 97866.0 60295.0 70630.0 95631.0 60562.0 True False 78741.88229161868 68101.94816388191 102454.96565584144 81809.36991242776 87177.92078972254 93680.49931678872 63416.78007429919 73911.72764749167 84860.02974092604 71030.06100620748 1.1085712327452069 0.9587764278835453 1.4424169739469554 1.1517569991285557 1.2273383910243842 1.3188852436520047 0.8928160721804399 1.0405696771263135 1.194705854659338 1.0 16.116142103971022 -7.256371447102162 24.998943552769376 1.0354037082773273 1.200160205337026 0.2660937921179507 0.13766216321392977 636.3217510949935 3138837.1536003402 0.05502182800281868 0.041287162246094154 5.541515507320525e-08 7.256371447102162 0.16475649705969864 LLIHQS(ph)LAGGIIGVK ddPTM_PC-9_AZD4547_30min_R2 1 LLIHQSLAGGIIGVK 15 0 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 LLIHQS(1)LAGGIIGVK 82.48200000000001 0.0043927 1091900.0 11135.0 11274.0 14071.0 19203.0 14608.0 17112.0 9752.6 15181.0 10322.0 11742.0 True False 14675.69837761196 14918.100024913889 13884.409346171926 14776.045033392506 12579.931352434503 16041.983934884096 10620.562506710387 12835.125274675502 10867.599847219351 11330.916153986642 1.295190801711872 1.3165837450544668 1.2253562869483303 1.3040468072119427 1.1102307334617785 1.4157711271422588 0.9373083661000945 1.1327526477335748 0.959110428453371 1.0 13.467976893609725 -7.270431605697709 24.999493511864067 1.0183555754688263 1.2708070959788276 0.696653846305805 0.0872710417375874 382.6517270370685 1063814.5690430957 0.03399498391005578 0.02329869549908884 5.364983545341658e-08 7.270431605697709 0.2524515205100013 LLIVQDAS(ph)ER ddPTM_PC-9_AZD4547_30min_R2 1 LLIVQDASER 10 0 C9JPX5;C9JKL2;O95772-2;O95772 C9JPX5 STARD3NL MLN64 N-terminal domain homolog 1 LLIVQDAS(1)ER 80.69 0.042832999999999996 0.0 8060.8 13523.0 12768.0 16421.0 14333.0 7566.3 11390.0 16890.0 10851.0 13029.0 True False 10623.966724944265 17894.045293321848 12598.687977536996 12635.39215192096 12343.110355588968 7093.178064896771 12403.687934646276 14280.03859358864 11424.561707244447 12572.85867571896 0.8449921373459444 1.4232280625152738 1.002054369852094 1.0049736879905256 0.9817266441900211 0.5641658947933063 0.9865447671499409 1.135782956120125 0.9086685853956081 1.0 13.618025090436815 -5.506666525975228 23.625792079002995 0.9392628622817643 1.1537428947681554 0.13864864670389643 0.1898022238400125 584.4558878833774 851713.7118129267 0.05012690107822687 0.09973414319259817 3.1141065932739136e-06 5.506666525975228 0.21448003248639114 LLIVSTTPYSEK ddPTM_PC-9_Lapatinib_30min_R1 1 LLIVSTTPYSEK 12 0 Q9Y230;Q9Y230-2;M0R0Y3 Q9Y230 RUVBL2 RuvB-like 2 0 110.53 0.0054427 2219600.0 25175.0 20406.0 23957.0 22695.0 22310.0 21149.0 26851.0 21839.0 22661.0 27430.0 False True 24815.999883470417 20358.751160740896 21987.347936694317 24364.066008300622 20997.769663147614 20244.50657072693 28241.21339704798 22853.719667189187 20108.67954909101 32171.238951822466 0.7713722160540111 0.6328245919042417 0.6834473477885363 0.7573244550757479 0.6526876286795324 0.629273451390659 0.877840403950254 0.7103773560419422 0.6250514498121894 1.0 14.973483876473633 -11.196354706023502 2.5968053134609503 1.0418675504210637 0.7048344667113662 0.577187171581073 0.07588226141514304 12133851.389473375 10168339.917297231 3359367.0337594487 0.019592190365460532 6.362756363577505e-12 11.196354706023502 -0.33703308370969753 LLKEGEEPT(ph)VYSDEEEPKDESAR ddPTM_PC-9_AZD4547_30min_R2 1 LLKEGEEPTVYSDEEEPKDESAR 23 2 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 LLKEGEEPT(0.661)VY(0.155)S(0.185)DEEEPKDESAR 67.396 0.0006959 8921600.0 32382.0 23366.0 32460.0 35939.0 29279.0 21011.0 30831.0 23318.0 22323.0 21706.0 True False 42678.80241255773 30918.602552965905 32029.55919101277 27653.818802014957 25214.116242328175 19697.17884851855 33574.899272438895 19714.73889433394 23502.948206692272 20946.0795467922 2.0375556350397703 1.4761045132047612 1.5291433950425322 1.32023841216864 1.2037630328864861 0.9403754437443205 1.602920450933776 0.9412137889714625 1.1220690800007798 1.0 14.354392621198034 -1.5228787455269135 0.43617024191732034 1.1028560453351166 19.361026089366824 0.6783214952027145 0.18859054830719682 49.12942361269628 0.6097500907936715 0.11959923042119473 791.6212938034655 0.029999999982967138 1.5228787455269135 18.258170044031708 LLKEGEEPTVY(ph)SDEEEPKDESAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLKEGEEPTVYSDEEEPKDESAR 23 2 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 LLKEGEEPT(0.072)VY(0.633)S(0.294)DEEEPKDESAR;LLKEGEEPT(0.031)VY(0.882)S(0.087)DEEEPKDESAR 88.471 5.0385e-05 59917000.0 182229.0 121658.5 110290.6 162478.0 237583.0 183942.0 179931.0 167741.0 135905.0 156220.0 True False 213076.77051319074 133735.9518669837 112920.34618342987 153374.88442078308 191030.31665383576 174295.75770861542 162886.63309236983 163337.9764862806 137892.35351800008 184541.4493631608 1.154628248821624 0.7246932996814364 0.6118969292433208 0.8311134704429207 1.0351621129728177 0.9444802688506971 0.8826560843348734 0.8851018405347316 0.74721616197259 1.0 17.493585367007327 -4.746373406184584 24.980941161775675 0.8492928573697698 1.1546290711514615 0.353431190967058 0.12302361884856047 1039.2812375009871 1723139.279818504 0.033355340179815576 0.7658104753457337 1.793191178924962e-05 4.746373406184584 0.30533621378169173 LLKEGEEPTVY(ph)SDEEEPKDESAR ddPTM_PC-9_Lapatinib_30min_R1 1 LLKEGEEPTVYSDEEEPKDESAR 23 2 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 LLKEGEEPT(0.02)VY(0.506)S(0.474)DEEEPKDESAR 70.837 0.0018695 354010000.0 89240.0 86539.0 19679.0 17682.0 16981.0 25300.0 25397.0 18482.0 27251.0 7731.0 True False 87967.4212353885 86338.62426244013 18061.06858313677 18982.393265422863 15982.21096593051 24217.977977180566 26711.932391524613 19340.741191858186 24181.705414248252 9067.293049090033 9.701618857925482 9.521984543237503 1.9918920106976499 2.093501683760831 1.7626220835042314 2.670915988494605 2.9459654879253456 2.1330226217624197 2.66691561454221 1.0 13.14645619731877 -5.259900675994097 24.980510630334084 2.2285903870228267 9.611802541101037 0.970206550433711 0.5223515878197859 18.272791151211692 296647.68023825646 0.13251026658547763 0.31457239707290885 5.4966656931387315e-06 5.259900675994097 7.38321215407821 LLKEGEEPTVYS(ph)DEEEPK ddPTM_PC-9_Lapatinib_30min_R1 1 LLKEGEEPTVYSDEEEPK 18 1 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 LLKEGEEPTVYS(1)DEEEPK 124.08 5.0208000000000004e-05 0.0 43220.0 29451.0 8746.3 5360.4 11027.0 12542.0 10966.0 10165.0 12537.0 5423.3 True False 42603.67487442271 29382.80801896403 8027.212975694342 5754.621697770196 10378.413539916122 12005.607896829979 11533.765822949907 10637.303009156933 11124.951039537274 6360.710178906992 6.697943103224931 4.619422547564193 1.2619994858928971 0.9047137089901265 1.6316438334719916 1.8874634371240904 1.813282715064977 1.6723451800133455 1.7490108378824072 1.0 12.634972137339638 -5.063974989086218 2.7837512555472546 1.5181524807925286 6.619728590637022 0.9583278737796113 0.35931425744079554 0.05650491238125239 0.802251799554654 0.10674889438152903 0.48347900145856915 8.630282479231323e-06 5.063974989086218 5.101576109844494 LLKEGEEPTVYS(ph)DEEEPKDESAR ddPTM_PC-9_AZD4547_30min_R2 7 LLKEGEEPTVYSDEEEPKDESAR 23 2 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 LLKEGEEPT(0.005)VY(0.462)S(0.533)DEEEPKDESAR;LLKEGEEPT(0.038)VY(0.204)S(0.758)DEEEPKDES(0.001)AR;LLKEGEEPT(0.012)VY(0.17)S(0.818)DEEEPKDESAR;LLKEGEEPT(0.001)VY(0.121)S(0.878)DEEEPKDESAR;LLKEGEEPT(0.003)VY(0.026)S(0.971)DEEEPKDESAR;LLKEGEEPT(0.016)VY(0.456)S(0.528)DEEEPKDES(0.001)AR;LLKEGEEPT(0.001)VY(0.021)S(0.978)DEEEPKDESAR 90.712 3.3617e-05 1047449400.0 443744.0 394834.0 453309.0 478310.0 441396.0 286195.0 400378.0 332704.0 324457.0 342429.0 True False 584845.3615514176 522456.3691003062 447297.8264731613 368043.01931583404 380115.7844495605 268299.1814074423 436010.8663650404 281292.2415773433 341607.1346279059 330440.6649372751 1.7698952447709004 1.5810898129002369 1.3536403776395627 1.1137945730308243 1.1503299223832357 0.8119435949518241 1.3194830801100248 0.8512639981242586 1.0337926619677709 1.0 18.33403171414008 -5.276614792299622 0.9751124276168551 1.0119763884532207 1.8983822349488826 0.7950063050981097 0.132590395803607 0.430916230886368 0.5459076069719296 0.045454449430401576 0.3406849804696185 5.28914176645475e-06 5.276614792299622 0.8864058464956619 LLKEGEEPTVYS(ph)DEEEPKDESAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 LLKEGEEPTVYSDEEEPKDESAR 23 2 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 LLKEGEEPT(0.002)VY(0.452)S(0.546)DEEEPKDESAR;LLKEGEEPT(0.235)VY(0.26)S(0.505)DEEEPKDESAR;LLKEGEEPT(0.043)VY(0.145)S(0.811)DEEEPKDESAR;LLKEGEEPT(0.009)VY(0.028)S(0.963)DEEEPKDESAR;LLKEGEEPT(0.001)VY(0.017)S(0.982)DEEEPKDESAR;LLKEGEEPT(0.003)VY(0.125)S(0.872)DEEEPKDESAR;LLKEGEEPT(0.027)VY(0.439)S(0.534)DEEEPKDESAR;LLKEGEEPT(0.047)VY(0.43)S(0.523)DEEEPKDESAR 105.52 7.6245e-07 207283000.0 412936.0 278381.9 265379.0 368083.0 514225.0 392031.0 393755.0 378167.0 343520.0 317768.3 True False 482837.90894223563 306017.8152701166 271706.6418154623 347460.5028511869 413466.3026450485 371472.20422886714 356455.6758606696 368240.5169510569 348543.33012400835 375377.1773375214 1.2862740147574039 0.8152275464391376 0.7238230191367137 0.9256303361745588 1.101468942724984 0.9895972015764211 0.9495933620390605 0.9809880279960453 0.9285149741818605 1.0 18.51798141245083 -4.749108847067398 24.978741744025175 0.9348634769877103 1.2862748317733674 0.5355578963944201 0.09814112428008884 518.3968038980574 1050084.7352992431 0.02732089335044026 0.46533007300560575 1.7819321064840916e-05 4.749108847067398 0.3514113547856571 LLKEGEEPTVYS(ph)DEEEPKDESAR ddPTM_PC-9_Lapatinib_30min_R1 8 LLKEGEEPTVYSDEEEPKDESAR 23 2 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 LLKEGEEPT(0.008)VY(0.444)S(0.548)DEEEPKDESAR;LLKEGEEPT(0.034)VY(0.239)S(0.727)DEEEPKDESAR;LLKEGEEPT(0.043)VY(0.155)S(0.802)DEEEPKDESAR;LLKEGEEPT(0.001)VY(0.447)S(0.552)DEEEPKDESAR;LLKEGEEPTVY(0.003)S(0.997)DEEEPKDESAR;LLKEGEEPTVY(0.011)S(0.988)DEEEPKDESAR;LLKEGEEPT(0.052)VY(0.438)S(0.508)DEEEPKDES(0.003)AR;LLKEGEEPTVY(0.005)S(0.994)DEEEPKDESAR 121.84 3.0156e-08 780326300.0 1288355.0 861159.0 356996.8 257341.1 293727.9 306808.3 304914.0 260576.1 456725.4 107984.6 True False 1269982.8214446306 859165.0392449514 327645.9011514993 276266.82295874384 276451.40241327 293686.8242140792 320700.9549643397 272683.4168858218 405284.17592032166 126649.59422956512 10.027531704070517 6.783796225099849 2.587026852668854 2.181347872761301 2.1828052754134695 2.318892737087987 2.532190939222726 2.153054011302679 3.200043224660502 1.0 16.95048292926905 -5.033855574324186 2.0533405811901946 2.2545157877351985 10.514404245618747 0.9589188993735489 0.5292561710531857 0.07398153521991893 0.4959548718654178 0.13993380970290253 0.9456108105423077 9.250057356801643e-06 5.033855574324186 8.259888457883548 LLKGNS(ph)PPAALGPQDPAPA ddPTM_PC-9_AZD4547_30min_R2 1 LLKGNSPPAALGPQDPAPA 19 1 Q9ULV8-2;Q9ULV8 Q9ULV8-2 CBLC E3 ubiquitin-protein ligase CBL-C 1 LLKGNS(1)PPAALGPQDPAPA 69.111 0.03846 10841000.0 37023.0 26317.0 55781.0 89867.0 76659.0 46765.0 42496.0 51439.0 41788.0 49445.0 True False 48795.54387376086 34823.45559301567 55041.307493342094 69149.5515813093 66016.22108065982 43840.77715724957 46278.06167433962 43490.28450062795 43996.82836810718 47713.94559988672 1.022668388880351 0.7298381040426543 1.1535685594920235 1.4492524294925102 1.383583358086751 0.9188252324568533 0.9699064098033738 0.9114795256154881 0.9220957901291574 1.0 15.542123371300873 LLKGNS(ph)PPAALGPQDPAPA ddPTM_PC-9_Lapatinib_30min_R1 1 LLKGNSPPAALGPQDPAPA 19 1 Q9ULV8-2;Q9ULV8 Q9ULV8-2 CBLC E3 ubiquitin-protein ligase CBL-C 1 LLKGNS(1)PPAALGPQDPAPA 90.71799999999999 0.008812899999999999 0.0 86497.0 32680.0 40722.0 37855.0 36421.0 29578.0 21048.0 28185.0 33720.0 21439.0 True False 85263.53691839287 32604.331467853233 37373.9943514658 40638.98298057809 34278.788386441025 28313.017889685612 22137.762451345054 29494.577994401192 29922.09851265827 25144.702584328174 3.3909145130050056 1.2966680102302897 1.4863565884752092 1.6162045601568167 1.363260840786632 1.1260032921340712 0.8804145675257562 1.1729937109212079 1.1899961199504376 1.0 14.61796686863318 -4.760990944282521 6.6575117753436635 1.2477944137648254 3.4466924174760267 0.9074281037108906 0.20643096426570273 0.036610957443807456 8.131352499241178 0.05831217345832463 0.36417197666767004 1.7338401506492732e-05 4.760990944282521 2.1988980037112014 LLKPGEEPSEYT(ph)DEEDTKDHNKQD ddPTM_PC-9_Lapatinib_30min_R1 3 LLKPGEEPSEYTDEEDTKDHNKQD 24 3 O15173;O15173-2;U3KPU8;U3KQM0 O15173 PGRMC2 Membrane-associated progesterone receptor component 2 1 LLKPGEEPS(0.01)EY(0.147)T(0.815)DEEDT(0.028)KDHNKQD;LLKPGEEPS(0.003)EY(0.032)T(0.959)DEEDT(0.006)KDHNKQD;LLKPGEEPS(0.001)EY(0.15)T(0.837)DEEDT(0.012)KDHNKQD 88.176 2.9694e-05 64763000.0 347320.0 339878.0 128667.0 121087.0 114609.0 132574.0 138496.0 139641.0 177725.0 56014.3 True False 342367.1531093122 339091.0333730422 118088.49592898322 129992.1419143908 107867.9239499636 126904.11906508816 145666.64521386736 146129.2306445336 157707.73897278158 65696.29712063688 5.211361493945843 5.16149384721601 1.797490895295659 1.978682933616314 1.6419178656582083 1.9316784145696446 2.217273295424587 2.224314566408503 2.400557503007906 1.0 16.003524436912244 -5.259542728093094 24.97093989193161 1.9489147167988128 5.186428047721188 0.9264150216666805 0.3703896361057698 35.88431895737318 472436.4942468334 0.09320686386898239 0.2222932039691177 5.501197942735682e-06 5.259542728093094 3.2375133309223756 LLLAADPGGS(ph)PAQR ddPTM_PC-9_AZD4547_30min_R2 3 LLLAADPGGSPAQR 14 0 Q5SQI0-7;Q5SQI0-6;Q5SQI0-5;Q5SQI0-4;Q5SQI0-3;Q5SQI0-2;Q5SQI0 Q5SQI0-7 ATAT1 Alpha-tubulin N-acetyltransferase 1 1 LLLAADPGGS(1)PAQR;LLLAADPGGS(1)PAQR;LLLAADPGGS(1)PAQR 150.12 0.00018608 17900700.0 42220.0 50550.0 88717.0 107730.0 80055.0 88444.0 84869.0 89348.0 71605.0 84347.0 True False 55645.08176944558 66889.29894087261 87540.55461334194 82894.51291190827 68940.74509988661 82913.58269850932 92422.1765869617 75541.31961278606 75389.8941154952 81394.03720322855 0.6836505926166098 0.821796058277097 1.0755155736379862 1.0184347129131002 0.8469999458037945 1.0186690026381993 1.135490752918393 0.9280940251700607 0.9262336247956111 1.0 16.312635488384622 -5.023256551107605 3.73501147337881 0.9921820588997571 0.6987274412031349 0.6296436721626232 0.07719193455155325 0.14243174480168835 4.224180976581162 0.02095284151594495 0.08219390356735026 9.478583687939165e-06 5.023256551107605 -0.2934546176966222 LLLAADPGGS(ph)PAQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LLLAADPGGSPAQR 14 0 Q5SQI0-7;Q5SQI0-6;Q5SQI0-5;Q5SQI0-4;Q5SQI0-3;Q5SQI0-2;Q5SQI0 Q5SQI0-7 ATAT1 Alpha-tubulin N-acetyltransferase 1 1 LLLAADPGGS(1)PAQR;LLLAADPGGS(1)PAQR;LLLAADPGGS(1)PAQR;LLLAADPGGS(1)PAQR 134.02 1.2605e-05 22838600.0 57114.0 73562.0 90579.0 88485.0 95025.0 80388.0 94961.0 68177.0 85514.0 69176.0 True False 66782.27214708054 80864.74920567875 92738.74688277037 83527.47232224062 76405.53339267024 76172.31176501393 85965.60662189692 66387.42598950247 86764.48047340628 81717.06120308524 0.8172378101203567 0.9895699626876167 1.1348761876334952 1.0221546283297696 0.9350009932783234 0.9321469793891467 1.0519909227799211 0.8124059408415927 1.061767018980003 1.0 16.318349700801548 -6.259121436521759 24.906018771235605 0.9588239706036547 1.0011401365606278 0.008913707609536137 0.09796485549211228 807.5133679531571 8676606.185674734 0.02964881413238036 0.03649264036786424 5.506537022311691e-07 6.259121436521759 0.042316165956973184 LLLAADPGGS(ph)PAQR ddPTM_PC-9_Lapatinib_30min_R1 3 LLLAADPGGSPAQR 14 0 Q5SQI0-7;Q5SQI0-6;Q5SQI0-5;Q5SQI0-4;Q5SQI0-3;Q5SQI0-2;Q5SQI0 Q5SQI0-7 ATAT1 Alpha-tubulin N-acetyltransferase 1 1 LLLAADPGGS(1)PAQR;LLLAADPGGS(1)PAQR;LLLAADPGGS(1)PAQR 145.46 0.00018547 15712000.0 106131.0 119699.0 83932.0 90241.0 82484.0 76218.0 75211.0 77950.0 54694.0 60408.0 True False 104617.55247795825 119421.84431978493 77031.43494688942 96877.62417515104 77632.45328978337 72958.33381283579 79105.05756975058 81571.84157046574 48533.78576664685 70849.44231139953 1.4766178683261915 1.685572114949029 1.087255346461566 1.367373136818095 1.0957383820831075 1.0297658165348316 1.1165233626267055 1.1513406303459497 0.6850270684323773 1.0 16.112468876620127 -4.949543405954113 0.39886473093176117 0.9337800086502156 2.020256793186347 0.622020187841188 0.1624420008849642 3.250283382297206 0.45178061455224633 0.1333934027709025 1.6745361555575475 1.1231987049555286e-05 4.949543405954113 1.0864767845361314 LLLAEDS(ph)EEEVDFLSER ddPTM_PC-9_AZD4547_30min_R2 2 LLLAEDSEEEVDFLSER 17 0 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 LLLAEDS(0.999)EEEVDFLS(0.001)ER;LLLAEDS(1)EEEVDFLSER 105.63 0.00070969 12487400.0 12505.7 11609.0 15935.8 20687.7 15195.9 13301.1 10109.7 17775.4 11416.7 12891.1 True False 16482.2524652808 15361.382223631832 15724.48087973326 15918.470386778834 13086.21158532719 12469.380114322503 11009.443714916015 15028.62036805659 12020.163454345005 12439.786512745462 1.324962646938799 1.2348589911806753 1.2640474869582683 1.2796417663976152 1.0519643220500141 1.002378947705149 0.8850187021807844 1.208109186814314 0.9662676640012654 1.0 13.602674106203956 -6.302792248156602 4.362853507437905 1.0187900998092045 1.2733896537129394 0.720494238605422 0.07857381365412151 0.11864694769643638 5.147368433072948 0.02455940912457198 0.028884858477231014 4.979752425842249e-07 6.302792248156602 0.2545995539037349 LLLAEDS(ph)EEEVDFLSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LLLAEDSEEEVDFLSER 17 0 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 LLLAEDS(1)EEEVDFLSER;LLLAEDS(1)EEEVDFLSER;LLLAEDS(1)EEEVDFLSER 103.39 0.006509899999999999 0.0 6880.89 4241.5599999999995 6078.34 4083.77 8282.42 8233.76 7536.9400000000005 9928.76 8906.72 3259.12 True False 8045.688773227676 4662.634045306519 6223.270677832818 3854.9696066609736 6659.53925684945 7801.967130893922 6822.986480479765 9668.140570390797 9036.963930141223 3849.972656820274 2.0898041337968047 1.2110823792596566 1.616445422491045 1.0012979182675097 1.729762741315057 2.026499361514332 1.772216867149111 2.511223177978567 2.3472800291534877 1.0 11.910632484233295 -6.558041770715091 4.770126568641007 2.00950444070156 1.4577848040287742 0.1633334348035267 0.46249298927802107 0.2859653181966937 15.554414383684648 0.1492787600893379 0.1526364494204379 2.766675532029929e-07 6.558041770715091 -0.5517196366727857 LLLAEDS(ph)EEEVDFLSER ddPTM_PC-9_Lapatinib_30min_R1 1 LLLAEDSEEEVDFLSER 17 0 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 LLLAEDS(1)EEEVDFLSER 124.5 4.0408000000000003e-05 7044900.0 3328.7 3371.8 5256.1 2167.8 4204.3 4488.0 2175.5 2744.0 3778.2 2337.3 True False 3281.2321275911827 3363.9928042627766 4823.963747132734 2327.227243568808 3957.0113399718307 4296.058702038987 2288.1367451967467 2871.4962574644987 3352.6593297902 2741.2991907435176 1.1969624252146005 1.2271527367833086 1.7597363189766744 0.8489504726179116 1.4434802860385982 1.5671615548369875 0.8346906287803411 1.047494657701215 1.2230183925603773 1.0 11.420644079971352 -7.265400732124095 24.99280368369033 1.030258817025624 1.3368023256810335 0.28665562872366346 0.24279874430023884 480.64401431145524 3032439.0700388886 0.09837993556587987 0.06915425795973679 5.4274929484070973e-08 7.265400732124095 0.3065435086554096 LLLAS(ph)PPNER ddPTM_PC-9_AZD4547_30min_R2 4 LLLASPPNER 10 0 Q52LW3 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 LLLAS(1)PPNER;LLLAS(1)PPNER;LLLAS(1)PPNER;LLLAS(1)PPNER 116.03 0.001075 157777000.0 86028.0 79185.0 123398.0 166345.0 138555.0 129541.0 122349.0 143991.0 108634.0 119730.0 True False 113383.11450643932 104780.00270292761 121761.66189317907 127996.7302546309 119319.02988338991 121440.78079177297 133237.82397858123 121740.49953400984 114376.17145929344 115538.28914297576 0.9813466630627579 0.9068855310230963 1.053864158768199 1.1078295446822666 1.0327228381903386 1.0510868881007318 1.1531919415363918 1.0536809955992943 0.9899417094341407 1.0 16.818011511381556 -5.293990841974507 10.899001119320213 1.0616555600301192 0.9441432044633833 0.45498474237789166 0.048270417013707025 0.6218573618405492 207.50722882335154 0.01263858621084993 0.026537839346108958 5.081701582992833e-06 5.293990841974507 -0.1175123555667359 LLLAS(ph)PPNER ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LLLASPPNER 10 0 Q52LW3 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 LLLAS(1)PPNER;LLLAS(1)PPNER;LLLAS(1)PPNER;LLLAS(1)PPNER;LLLAS(1)PPNER 139.76 0.00011552 121162500.0 104881.2 112992.0 149909.0 165538.0 170621.0 157580.7 153968.1 143867.7 138366.3 101281.7 True False 122635.51566187586 124209.09902188665 153483.3990930485 156263.44254143717 137189.03986309664 149316.89068703202 139383.12693548758 140091.32531542858 140389.64537417787 119643.270464504 1.0250097242055882 1.0381620173007327 1.282841889035324 1.3060779928094468 1.1466507002898934 1.248017461469608 1.1649892751539255 1.170908524746414 1.1734019375191598 1.0 16.86837972680405 -10.473518901618363 14.790777014168189 1.0000001954525086 1.177230188458617 0.2591767352733928 0.08741682673504596 0.0 0.0 0.09080555383877768 0.022023581757058333 3.361097403640816e-11 10.473518901618363 0.1772299930061083 LLLAS(ph)PPNER ddPTM_PC-9_Lapatinib_30min_R1 5 LLLASPPNER 10 0 Q52LW3 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 LLLAS(1)PPNER;LLLAS(1)PPNER;LLLAS(1)PPNER;LLLAS(1)PPNER;LLLAS(1)PPNER 142.89 0.00012173 107126700.0 156700.0 137239.0 144084.0 110430.0 131344.0 133709.0 119438.0 115587.0 134535.0 90350.7 True False 154465.42926473927 136921.231527439 132237.96970032412 118551.39058368087 123618.60415223926 127990.57776090247 125621.9152253777 120957.59399108929 119382.2515836443 105967.69811025991 1.4576652321353365 1.2921034802980413 1.2479082971372075 1.1187502672779357 1.1665687408215049 1.2078263474943811 1.1854736628766578 1.141457219021898 1.1265909679327608 1.0 16.69326503282742 -1.5228787452803376 0.527856773423883 1.1312144921423612 13.646701032328656 0.7875259208760268 0.053292464764246254 55.7396927060417 0.5466422682617654 0.027402941412446445 783.7301302460186 0.029999999999999995 1.5228787452803376 12.515486540186295 LLLATMESMNGGK ddPTM_PC-9_Lapatinib_30min_R1 5 LLLATMESMNGGK 13 0 P00352;Q5SYQ7;Q5SYQ9;Q5SYQ8 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ;;;; 267.39 6.9046e-55 73721800.0 256136.0 222762.0 232304.0 230148.0 262305.0 223859.0 237964.0 227158.0 207161.0 220845.0 False True 252483.4536704102 222246.20827545642 213204.8618393721 247073.85167122178 246876.7356114717 214285.0724108168 250284.61155320593 237712.58996104938 183828.34667795978 259017.76399253515 0.974772732875907 0.8580346183586911 0.8231283389718268 0.9538876711110147 0.9531266574387796 0.8272987501235338 0.9662835772160364 0.9177462823279573 0.7097132792917542 1.0 17.982691518854836 LLLDIPLQT(ph)PHK ddPTM_PC-9_AZD4547_30min_R2 2 LLLDIPLQTPHK 12 0 P49792;J3KQ37;F8VYC4;A0A286YES2;A0A1W2PNU4;J3KNE0;P0DJD0;P0DJD1;A6NKT7;Q99666;O14715 P49792;Q99666 RANBP2;RGPD8;RGPD1;RGPD3;RGPD2;RGPD5 E3 SUMO-protein ligase RanBP2;RANBP2-like and GRIP domain-containing protein 1;RANBP2-like and GRIP domain-containing protein 2;RanBP2-like and GRIP domain-containing protein 3;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8 1 LLLDIPLQT(1)PHK;LLLDIPLQT(1)PHK 137.73 0.00014108 34807000.0 130308.0 154450.0 144204.0 148528.0 163518.0 180546.0 147267.0 221250.0 169366.0 198645.0 True False 171743.23342522344 204372.9420656332 142291.76073878034 114287.16433472477 140816.3482261353 169256.43007875083 160373.47770601834 187060.89631921216 178318.34099245828 191690.49901283236 0.8959402490455535 1.0661610414606508 0.7422994956534329 0.5962067234593303 0.7346026482862285 0.8829672359891988 0.8366271595718598 0.9758485542191099 0.9302408930581432 1.0 17.548419307182293 -7.657432353113078 1.8263350008149437 0.97311128011533 0.8118386928835313 0.24233393084085875 0.1173050189940794 0.6125861724711488 4.000092186462025 0.09167444790144323 0.04050832083206982 2.2007344753150267e-08 7.657432353113078 -0.16127258723179871 LLLDIPLQT(ph)PHK ddPTM_PC-9_Lapatinib_30min_R1 2 LLLDIPLQTPHK 12 0 P49792;J3KQ37;F8VYC4;A0A286YES2;A0A1W2PNU4;J3KNE0;P0DJD0;P0DJD1;A6NKT7;Q99666;O14715 P49792;Q99666 RANBP2;RGPD8;RGPD1;RGPD3;RGPD2;RGPD5 E3 SUMO-protein ligase RanBP2;RANBP2-like and GRIP domain-containing protein 1;RANBP2-like and GRIP domain-containing protein 2;RanBP2-like and GRIP domain-containing protein 3;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8 1 LLLDIPLQT(1)PHK;LLLDIPLQT(1)PHK 158.65 0.0010171 29278000.0 154698.0 222441.0 238496.0 249751.0 238499.0 233060.0 177703.0 177068.0 207332.0 164399.0 True False 152491.97815186088 221925.95153123434 218887.77950118372 268118.5216849126 224470.9577270752 223092.56708939502 186903.59183254326 185295.22569851458 183980.08685725002 192815.14810210202 0.7908713586710071 1.1509777821694651 1.135220866491648 1.390546978927895 1.1641769847263783 1.1570282173642297 0.9693408099532284 0.9609993173378402 0.9541785936851106 1.0 17.55685887265043 -7.2641186321699065 23.136020974787122 0.9678795971703746 1.1457904216164394 0.24349515199799898 0.13702014643158625 120.47089747717911 1040275.8664146047 0.05777689418306945 0.04103318432698925 5.443539364478043e-08 7.2641186321699065 0.17791082444606476 LLLDT(ph)SPPGGVVLSSFR ddPTM_PC-9_AZD4547_30min_R2 1 LLLDTSPPGGVVLSSFR 17 0 A2AB89;O15211 A2AB89 RGL2 Ral guanine nucleotide dissociation stimulator-like 2 1 LLLDT(0.681)S(0.319)PPGGVVLSSFR 127.05 8.5929e-05 684400.0 7603.0 6822.2 8022.3 11945.0 9346.4 8313.6 8322.2 10928.0 7176.9 7467.1 True False 10020.595847775812 9027.342734607728 7915.919060322301 9191.264798410326 8048.813690607467 7793.749277761359 9062.859677762355 9239.328700458063 7556.256282068253 7205.679101808352 1.3906525264580576 1.2528094308754614 1.0985666928098015 1.2755584405783027 1.1170097331405613 1.0816120406757253 1.2577384518119772 1.2822287212511785 1.048652899373762 1.0 12.814918688780624 -1.5228787455535553 0.02262016042547336 1.226968096364058e-10 2.7509495409567797 0.3980348204977011 0.09350053785374468 2970.1422093909487 5.191211692057419 225.17465802519976 438.89592854214175 0.029999999981126787 1.5228787455535553 2.7509495408340827 LLLDTS(ph)PPGGVVLSSFR ddPTM_PC-9_Lapatinib_30min_R1 2 LLLDTSPPGGVVLSSFR 17 0 A2AB89;O15211 A2AB89 RGL2 Ral guanine nucleotide dissociation stimulator-like 2 1 LLLDT(0.309)S(0.69)PPGGVVLSSFR;LLLDT(0.373)S(0.625)PPGGVVLS(0.001)S(0.001)FR 86.777 0.0030077 4428300.0 35960.0 30477.0 36720.0 29466.0 35132.0 32369.0 28610.7 29775.8 35352.0 23152.8 True False 35447.203805743644 30406.4323790013 33701.02334329906 31633.027935694503 33065.60483216954 30984.65332582439 30092.02205276976 31159.292369902094 31370.285486936416 27154.730630833223 1.3053785834831524 1.1197471553805762 1.2410737488602723 1.1649177583730599 1.217673829348347 1.1410407176214972 1.1081686819828493 1.147471974349907 1.1552420060214694 1.0 14.728915931653818 -14.522878744642057 0.07556335078813728 0.4059596273572901 1.367445613935379 0.6236564979170605 0.04811098864942042 181.11055103327428 0.9727967987565591 18.19111158178872 1.9187358083333506 3.000000004409087e-15 14.522878744642057 0.9614859865780889 LLLELNAVQHNPPGFPA ddPTM_PC-9_AZD4547_30min_R2 2 LLLELNAVQHNPPGFPA 17 0 F8W1E0 F8W1E0 PXN 0 ; 141.1 0.00044032 6852700.0 15318.6 9296.900000000001 17692.8 26363.0 21643.8 20310.9 14557.1 18941.0 17167.3 19080.1 False True 20189.59615332612 12301.941114211626 17458.18191172984 20285.417654289777 18638.93196918277 19040.85621219245 15852.6536991606 16014.103670879967 18074.72843026242 18412.11150653045 1.096538881277426 0.6681439611012754 0.9481901033207262 1.1017431459229918 1.0123190902125414 1.0341484302568447 0.860990532972709 0.8697592161116365 0.9816760247107799 1.0 14.168367464429588 -4.46521774107572 23.588383034720234 0.9418454243134167 4.641463637198884 0.14139920466579825 0.11432793886673506 1321.8326842012107 568344.8058788932 0.028743090423794342 12989.506723684219 3.425959770413387e-05 4.46521774107572 3.699618212885467 LLLERPS(ph)PIR ddPTM_PC-9_AZD4547_30min_R2 1 LLLERPSPIR 10 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 LLLERPS(1)PIR 77.74 0.010074 9777800.0 23335.0 20748.0 27851.0 30898.0 27938.0 28139.0 24057.0 30072.0 23258.0 24221.0 True False 30755.044601847767 27454.38525074624 27481.67754247988 23774.94346934132 24059.290944983244 26379.463881703083 26198.026395415753 25425.06338581395 24487.370397851937 23373.03016229863 1.315834720115004 1.1746181415121328 1.1757858245872037 1.0171956012657266 1.0293612243649766 1.1286283249766185 1.1208656393073895 1.0877949161604776 1.0476763272804384 1.0 14.512557161883034 -4.838148402699549 1.166507038191111 1.0712421907006813 1.405592188904262 0.7277524371141862 0.04751530700034543 0.8091764663470988 0.992349171321449 0.015388664409533272 0.32413083588563474 1.451615501522501e-05 4.838148402699549 0.3343499982035807 LLLERPS(ph)PIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLLERPSPIR 10 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 LLLERPS(1)PIR 54.005 0.045473 29589000.0 19528.0 21124.0 25043.0 22501.0 24146.0 15857.0 18793.0 16687.0 14377.0 14881.0 True False 22833.704704419037 23221.051116347488 25640.120096106373 21240.34191922625 19414.76463351132 15025.43100534688 17012.790990462454 16248.983931337983 14587.236426388212 17578.80750206881 1.2989336564344192 1.320968507881701 1.4585813112231218 1.2082925372910833 1.1044415061275596 0.8547468878977469 0.967801199737824 0.9243507518599131 0.8298194530357917 1.0 14.101549584888318 -6.3397692092843725 1.8891652620375112 0.9137319491016171 1.3521085754583786 0.8840846938510145 0.06978271847899016 0.10274942376494597 0.7230260380325355 0.024164742155409362 0.029936240537705223 4.573311578074294e-07 6.3397692092843725 0.43837662635676145 LLLERPS(ph)PIR ddPTM_PC-9_Lapatinib_30min_R1 1 LLLERPSPIR 10 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 LLLERPS(1)PIR 94.538 0.0029555 61689000.0 65696.0 77546.0 74614.0 60867.0 74876.0 69324.0 63144.0 67785.0 69620.0 65142.0 True False 64759.16299282912 77366.44700141191 68479.52493836911 65343.36222635975 70471.94089187986 66359.17412213702 66413.28735403524 70934.53856130864 61778.66246889877 76401.70790374115 0.8476140752562689 1.012627192822525 0.8963088236803132 0.8552604911487861 0.9223869835562809 0.8685561611494764 0.8692644336918443 0.9284417915196266 0.8086031603735088 1.0 16.221317268552845 -5.49465559828426 24.853921233279372 0.8883752866263324 0.936207479318202 0.048777177175085784 0.06093370584069313 1479.1679040440833 1302584.369538027 0.014574750479167876 0.030230505775839547 3.2014328852320537e-06 5.49465559828426 0.04783219269186967 LLLIGDSGVGK ddPTM_PC-9_Lapatinib_30min_R1 2 LLLIGDSGVGK 11 0 P62820;E7END7;P62820-2;Q9H0U4;E9PLD0;Q92928;P62820-3;P51153;P61006-2;P61026;Q92930;P59190-2;H0YL94;H0YMN7;A0A2R8YFB8;P59190;H0YNE9;H0YLJ8;G3V196;A0A2R8YDI9;P61006 P62820;P61006 RAB1A;RAB1B;RAB1C;RAB13;RAB8A;RAB10;RAB8B;RAB15 Ras-related protein Rab-1A;Ras-related protein Rab-1B;Putative Ras-related protein Rab-1C;Ras-related protein Rab-13;Ras-related protein Rab-8A;Ras-related protein Rab-10;Ras-related protein Rab-8B;Ras-related protein Rab-15 0 ; 142.43 0.00064918 7698000.0 79250.0 64428.0 73386.0 71718.0 70832.0 68513.0 83598.0 62877.0 77005.0 66736.0 False True 78119.88046732974 64278.820924444495 67352.48635815193 76992.38096423451 66665.80102106999 65582.85870160355 87926.29539184457 65798.49496377377 68331.88600140119 78271.22867986957 0.9980663621219127 0.82123178604166 0.8605012019630425 0.9836613307698853 0.8517280505935847 0.8378922856805834 1.123353968946423 0.8406472732514593 0.8730140966724768 1.0 16.256194471627218 LLLNNGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLLNNGAK 8 0 P15121;E9PCX2;E9PEF9 P15121 AKR1B1 Aldose reductase 0 105.2 0.01772 3860900.0 43483.0 45562.0 35533.0 41932.0 42726.0 34176.0 36573.0 41700.0 40798.0 35238.0 False True 50843.81307160249 50085.094251231974 36380.24147965291 39582.68598537823 34354.14701115731 32383.75039659048 33108.540674409815 40605.41918480216 41394.593567767 41626.37045614549 1.2214327724096874 1.2032058933410488 0.8739710207975131 0.950904091604135 0.8252976811262066 0.7779623839822317 0.7953741897648886 0.975473449638879 0.9944319697864922 1.0 15.345210150057381 -5.258515172400613 22.690270654939944 0.8894734163754832 1.212319496642931 0.7216791477829108 0.0775992866266425 35.727288862676986 277208.02550966083 0.021558025380278043 0.05192050174574135 5.514229376749346e-06 5.258515172400613 0.32284608026744777 LLLPGELAK ddPTM_PC-9_AZD4547_30min_R2 2 LLLPGELAK 9 0 Q16778;P33778;P23527;P06899;Q96A08;A0A2R8Y619;Q8N257;U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 Q16778;Q8N257;U3KQK0 HIST2H2BE;HIST1H2BB;HIST1H2BO;HIST1H2BJ;HIST1H2BA;HIST3H2BB;HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B type 2-E;Histone H2B type 1-B;Histone H2B type 1-O;Histone H2B type 1-J;Histone H2B type 1-A;Histone H2B type 3-B;Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 0 ; 123.72 0.006827199999999999 51475000.0 377910.0 368030.0 479240.0 609680.0 518310.0 463520.0 415290.0 523040.0 411730.0 477460.0 False True 498077.51898368594 486988.5002810935 472884.9644701462 469127.6954621018 446351.60318184044 434536.02112537867 452250.005476668 442216.186263506 433493.2072365454 460744.27072751377 1.0810281334529088 1.0569605119823633 1.0263501784264455 1.0181953965946242 0.9687621345286674 0.9431175789538254 0.9815640349961741 0.959786619951341 0.9408542542527137 1.0 18.813606700749894 -5.720963141821723 1.0453980282382502 0.9615124990715047 1.0790984377159765 0.8381722961200319 0.01819054805061524 0.22908748222955103 0.46864524457330364 0.006825340583009962 0.02125572306872542 1.9012396295571666e-06 5.720963141821723 0.11758593864447175 LLLPGELAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLLPGELAK 9 0 Q16778;P33778;P23527;P06899;Q96A08;A0A2R8Y619;Q8N257;U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 Q16778;Q8N257;U3KQK0 HIST2H2BE;HIST1H2BB;HIST1H2BO;HIST1H2BJ;HIST1H2BA;HIST3H2BB;HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B type 2-E;Histone H2B type 1-B;Histone H2B type 1-O;Histone H2B type 1-J;Histone H2B type 1-A;Histone H2B type 3-B;Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 0 ; 136.8 0.0045214 96283000.0 705990.0 745180.0 782030.0 809900.0 881060.0 757810.0 857350.0 689790.0 683660.0 566920.0 False True 825500.1630619029 819156.5456769458 800676.5610652887 764523.9287312272 708422.617742129 718069.1095517381 776135.6013235236 671683.7433929179 693657.2341423505 669698.1082637506 1.2326452066619724 1.2231728529152919 1.1955783526716404 1.1415948758065342 1.057823829872799 1.0722280691719341 1.1589335429597096 1.0029649704914283 1.0357760094928683 1.0 19.353151367225777 -4.565301710115394 0.26442011304768515 0.9944800979327337 1.495484927678388 0.7935755623277583 0.038481828879532845 4.790014865912017 0.2575592664342245 0.05415813717799129 0.7989457331742751 2.720810468372824e-05 4.565301710115394 0.5010048297456542 LLLPGELAK ddPTM_PC-9_Lapatinib_30min_R1 2 LLLPGELAK 9 0 Q16778;P33778;P23527;P06899;Q96A08;A0A2R8Y619;Q8N257;U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 Q16778;Q8N257;U3KQK0 HIST2H2BE;HIST1H2BB;HIST1H2BO;HIST1H2BJ;HIST1H2BA;HIST3H2BB;HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B type 2-E;Histone H2B type 1-B;Histone H2B type 1-O;Histone H2B type 1-J;Histone H2B type 1-A;Histone H2B type 3-B;Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 0 ; 138.54 0.0040644 367490000.0 1164450.0 1234350.0 1229800.0 1224500.0 1200350.0 1045270.0 1241440.0 997380.0 988680.0 1001280.0 False True 1147844.7294660255 1231491.9384132375 1128690.5911652795 1314553.814812257 1129747.7729789 1000566.2387433792 1305715.688787427 1043721.9159147037 877324.4471380489 1174349.9138782625 0.977429909008377 1.0486584312390033 0.9611194907298165 1.1193885223450772 0.9620197179969426 0.8520171261724141 1.1118625491062815 0.8887656937512237 0.7470724328157916 1.0 20.163430912866275 -7.9723555259024605 18.93435826991539 0.8549973941690878 1.001476750465047 0.2732955311940066 0.09332195362128648 15.752298865484994 10788.643613765384 0.04904025871100987 0.023551759745933588 1.0657233323884297e-08 7.9723555259024605 0.1464793562959592 LLNGPPRGIRAS(ph)S(ph)PMGR ddPTM_PC-9_Lapatinib_30min_R1 1 LLNGPPRGIRASSPMGR 17 2 S4R3J9;A0A2R8Y892;A0A2R8YFN1;Q9H5P4-2;Q9H5P4-1;Q9H5P4 S4R3J9 PDZD7 PDZ domain-containing protein 7 2 LLNGPPRGIRAS(1)S(1)PMGR 65.943 0.025384999999999998 9149700.0 108850.0 122190.0 139380.0 116470.0 143670.0 135420.0 119840.0 116480.0 144490.0 115800.0 True False 107297.77903935453 121907.0765623313 127920.7144223592 125035.59233253017 135219.6130660878 129628.40227943828 126044.72881837659 121892.08603114611 128216.01465284692 135815.8757061989 0.790023835442216 0.8975907708024096 0.9418686420656835 0.9206257492534308 0.9956097721491636 0.9544421931928964 0.9280559298608099 0.8974803968781003 0.9440429109348585 1.0 17.051292602501952 -4.613065605248534 1.5848290310494721 0.9455114516121698 0.676965344212474 0.7238978888477365 0.029650440472038412 0.9005436838546959 1.5732562100129728 0.008508889351732158 0.42555236058191825 2.4374425864155444e-05 4.613065605248534 -0.26854610739969575 LLPDDPYEK ddPTM_PC-9_Lapatinib_30min_R1 1 LLPDDPYEK 9 0 P78417-2;P78417;Q5TA01;Q5TA02;P78417-3 P78417-2 GSTO1 Glutathione S-transferase omega-1 0 103.55 0.012998 2601500.0 23975.0 22497.0 23167.0 20999.0 23730.0 21668.0 24301.0 19084.0 22000.0 25725.0 False True 23633.11210352348 22444.90957871156 21262.29868720613 22543.336510610497 22334.248054975047 20741.310150575042 25559.1868742938 19970.712309567214 19522.12832972959 30171.53197359214 0.7832917507870842 0.7439101732837641 0.7047139239007193 0.7471724183691343 0.7402424270177353 0.6874463705962637 0.847129237476727 0.6619058099882608 0.6470380207016494 1.0 14.880900331406686 -11.420756290758964 2.5301765892863655 1.1488753188719425 0.7300314920972508 0.679521272112253 0.055787749567149846 10621037.000658643 5975539.066676418 9422167.819941297 0.01405876473674449 3.7952790158533795e-12 11.420756290758964 -0.4188438267746917 LLPDPGS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLPDPGSPR 9 0 A6ND36 A6ND36 FAM83G Protein FAM83G 1 LLPDPGS(1)PR 93.44200000000001 0.0062531999999999996 2874200.0 15313.0 17934.0 25696.0 26466.0 34658.0 28996.0 29559.0 33630.0 24643.0 23595.0 True False 17905.188454463794 19714.36899832304 26308.690092622663 24983.195823929702 27867.01369453472 27475.398715459312 26758.957531372333 32747.24813393038 25003.35725502431 27872.586722082768 0.6423942145376106 0.7073031719264086 0.9438912274252225 0.8963357464105091 0.999800053450237 0.9857498691964326 0.9600457179732036 1.1748908868937356 0.8970590890731632 1.0 14.766559277863003 -4.886947671869585 0.788366639194574 1.0146041179721461 0.4242550455115198 0.74644994573142 0.07255494117579869 1.0656103412848665 0.5620115766223192 0.027358335943193906 0.5394068774722063 1.2973355774958365e-05 4.886947671869585 -0.5903490724606263 LLPDPGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 LLPDPGSPR 9 0 A6ND36 A6ND36 FAM83G Protein FAM83G 1 LLPDPGS(1)PR;LLPDPGS(1)PR;LLPDPGS(1)PR;LLPDPGS(1)PR 104.07 0.0027276999999999996 23004500.0 375845.0 353588.0 357088.0 334772.0 343001.0 335218.0 280750.0 311362.0 366068.0 302432.0 True False 370485.3813784685 352769.2887103815 327729.6030395419 359392.24964665493 322826.35554591176 320881.50757132453 295285.86127969983 325829.0152028644 324837.566973066 354706.96823469136 1.044482952286794 0.9945372386283998 0.9239446427302779 1.0132088789664362 0.9101212675706843 0.90463829669964 0.8324783207651121 0.9185864513021919 0.9157913321796872 1.0 18.43626814679868 -4.859424406907456 0.6544498438435887 0.9071470568744466 1.1137585507461993 0.4043837622607803 0.047275086784061414 2.9280005844329877 1.0165309033942063 0.022471222137899236 0.4470771797747531 1.3822149726499896e-05 4.859424406907456 0.2066114938717527 LLPEGEETLES(ph)DDEKDEHTSK ddPTM_PC-9_AZD4547_30min_R2 2 LLPEGEETLESDDEKDEHTSK 21 1 Q8N6N3 Q8N6N3 C1orf52 UPF0690 protein C1orf52 1 LLPEGEET(0.005)LES(0.995)DDEKDEHTSK;LLPEGEET(0.02)LES(0.968)DDEKDEHT(0.009)S(0.003)K 78.501 0.00046083 22726000.0 30606.0 21055.7 68523.0 146297.0 116428.0 118179.0 57537.0 106015.0 76785.0 108675.0 True False 40338.07135565256 27861.543258344784 67614.34024786716 112570.48691611845 100263.98189356842 110789.24844791193 62657.68153606166 89632.81773234444 80843.6983403157 104870.32132809579 0.38464716084402417 0.2656761503683922 0.6447423769812806 1.0734255935378707 0.9560758527656643 1.056440440392075 0.5974777300436769 0.8547014693692078 0.7708920628495957 1.0 16.678246922314578 -5.474729737917893 3.937728433139851 0.8911495563829295 0.3344585998846764 0.7354287326602146 0.1376526672765041 0.11535668067176694 3.682211137657321 0.03917743990305117 0.08327998570045475 3.351739535061159e-06 5.474729737917893 -0.5566909564982531 down LLPEGEETLES(ph)DDEKDEHTSK ddPTM_PC-9_Lapatinib_30min_R1 2 LLPEGEETLESDDEKDEHTSK 21 1 Q8N6N3 Q8N6N3 C1orf52 UPF0690 protein C1orf52 1 LLPEGEET(0.009)LES(0.988)DDEKDEHT(0.002)S(0.001)K;LLPEGEET(0.013)LES(0.973)DDEKDEHT(0.011)S(0.003)K 65.833 0.0017633 20377400.0 98732.0 74538.0 173742.0 98407.0 133619.0 174234.0 89541.0 122616.0 185861.0 105296.0 True False 97324.06357476884 74365.41184060092 159457.60342351487 105644.1790561289 125759.79312506151 166782.4179792917 94176.99485252224 128313.186991715 164927.37697690327 123496.27330189917 0.7880728784167461 0.6021672545438447 1.2911936462544467 0.855444267519482 1.01832864881379 1.3505056753540663 0.7625897716143791 1.0390045267037362 1.3354846471660045 1.0 16.914107981267087 -5.249171081650464 24.996175967575265 1.07084023255394 0.6951200338706099 0.39518689601279855 0.1908634732478416 763.5487971391597 1555694.0114101015 0.047399504999496044 0.12345658180170048 5.634156657386346e-06 5.249171081650464 -0.37572019868332995 LLPET(ph)VSPSAPSWR ddPTM_PC-9_AZD4547_30min_R2 1 LLPETVSPSAPSWR 14 0 B0QXZ6;O95503 B0QXZ6 CBX6 Chromobox protein homolog 6 1 LLPET(0.591)VS(0.269)PS(0.133)APS(0.008)WR 95.264 0.0079239 3039500.0 4893.8 7651.6 7032.0 7482.5 9723.0 11544.0 8016.0 12828.0 8445.0 7759.3 True False 6449.926602636497 10124.830064806723 6938.7510853728245 5757.525228472603 8373.129281196656 10822.151855090107 8729.40847095035 10845.727358114582 8891.385459190795 7487.649268747111 0.8614087507487842 1.3522041032379826 0.9266928559721211 0.7689362871875001 1.1182587459251694 1.445333704432573 1.1658409946344908 1.4484822898134182 1.187473550117094 1.0 12.87029714344961 -6.526661340686909 24.816535295595322 1.2732948951132605 0.9933636191255447 0.3117718899165214 0.18838283286108323 119.44635824506364 783642.5036666316 0.060898288709703735 0.06117371499929798 2.973984216530638e-07 6.526661340686909 -0.27993127598771583 LLPET(ph)VSPSAPSWR ddPTM_PC-9_Lapatinib_30min_R1 1 LLPETVSPSAPSWR 14 0 B0QXZ6;O95503 B0QXZ6 CBX6 Chromobox protein homolog 6 1 LLPET(0.732)VS(0.249)PS(0.019)APSWR 106.29 0.0021756 3237000.0 4351.8 6267.2 6038.9 5126.3 7961.0 7348.0 5630.8 6161.8 8038.2 5542.9 True False 4289.74253397762 6252.688683455617 5542.4049528281175 5503.305202835492 7492.749631928202 7033.743169024616 5922.335272284003 6448.099722756828 7132.853270001475 6500.982879550008 0.6598606108426719 0.96180666820775 0.8525487692426837 0.8465343325464081 1.1525564319663064 1.08195072950438 0.9109907504777095 0.9918653597812827 1.0971961320555277 1.0 12.666442139457681 -3.896400834338141 0.5881234637251044 1.0268189909677627 5.114957876345263e-13 0.5443590654989698 0.09306781783969621 8.200487745415591 0.987816397376382 0.04706799742478791 7.217634529127977 0.00012694019632674704 3.896400834338141 -1.0268189909672512 LLPETVS(ph)PSAPSWR ddPTM_PC-9_AZD4547_30min_R2 1 LLPETVSPSAPSWR 14 0 B0QXZ6;O95503 B0QXZ6 CBX6 Chromobox protein homolog 6 1 LLPET(0.11)VS(0.63)PS(0.259)APS(0.001)WR 155.09 0.00031552 3895900.0 7592.1 8815.5 9693.4 9291.0 10512.0 11881.0 6127.2 13301.0 7316.0 9180.9 True False 10006.229874509898 11664.937978501715 9564.859182444952 7149.103494519069 9052.590250328007 11138.07919181614 6672.50893004079 11245.636076573277 7702.708824089976 8859.479485448473 1.1294376707960032 1.3166617742793076 1.0796186387874198 0.8069439639497258 1.0217970779430907 1.257193406239071 0.753149091998041 1.2693337227140737 0.8694313065165429 1.0 13.113006224320305 -5.5120861554276575 24.334689415993047 1.0046762207524222 1.216822403540177 0.22712628530333479 0.16504018700765358 505.42707872334944 1139613.1044233914 0.041995107683981535 0.0795053374082637 3.0754866385543467e-06 5.5120861554276575 0.21214618278775466 LLPETVS(ph)PSAPSWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLPETVSPSAPSWR 14 0 B0QXZ6;O95503 B0QXZ6 CBX6 Chromobox protein homolog 6 1 LLPET(0.091)VS(0.454)PS(0.454)APS(0.001)WR 95.195 0.014427 0.0 7033.8 8636.0 11054.0 9341.2 9198.2 10544.0 9999.0 8502.2 7191.6 6965.5 True False 8224.483416117508 9493.32500666431 11317.56928252845 8817.842848579012 7395.878739831182 9991.054078348834 9051.822333508973 8279.026258825543 7296.763544829479 8228.290011132334 0.9995373771452298 1.1537421498051803 1.3754460850573478 1.0716494966328425 0.8988354481702815 1.2142321265817801 1.1000854759934875 1.0061660743149021 0.8867897868156613 1.0 13.006376928093358 -7.858219178194489 3.1464124876128046 0.9438068471471299 1.1223833699294603 0.2554619770834883 0.12166708369483577 0.36412687392581544 7.046841602255638 0.0821919138919402 0.0352218826473524 1.3860561424448736e-08 7.858219178194489 0.17857652278233038 LLPETVS(ph)PSAPSWR ddPTM_PC-9_Lapatinib_30min_R1 1 LLPETVSPSAPSWR 14 0 B0QXZ6;O95503 B0QXZ6 CBX6 Chromobox protein homolog 6 1 LLPET(0.189)VS(0.405)PS(0.405)APSWR 131.08 1.7466e-05 2821800.0 11330.0 14017.0 16829.0 15060.0 19662.0 16842.0 16030.0 17313.0 17310.0 13575.0 True False 11168.432122332471 13984.544497701907 15445.384581818624 16167.562638687255 18505.519816979322 16121.706920619567 16859.95496460762 18117.42518421386 15360.365517619068 15921.420662449511 0.7014720833721259 0.8783477802759333 0.970100904264554 1.0154597998166248 1.1623033025328184 1.0125796725315115 1.058947899314766 1.1379276741895024 0.9647609873060081 1.0 13.95868145231708 -4.802130574718425 1.0846385868397126 1.0612030191108872 0.5329586905070209 0.7806795298265115 0.05817881508754749 0.7207043544508214 0.7100815247350875 0.018066128422843386 0.43729179989755607 1.5771370173390918e-05 4.802130574718425 -0.5282443286038663 LLPLEEHYR ddPTM_PC-9_AZD4547_30min_R2 4 LLPLEEHYR 9 0 A0A024R571;Q9H4M9;C9JIJ3;C9IZH1;C9JC03;Q9NZN3-2;Q9NZN3;Q9NZN4 A0A024R571;Q9NZN4 EHD1;EHD3;EHD2 EH domain-containing protein 1;EH domain-containing protein 3;EH domain-containing protein 2 0 ;;; 148.52 1.2184e-11 0.0 8437.08 8235.43 8526.11 10977.5 8583.16 12374.599999999999 9772.5 8525.01 7370.58 7581.1 False True 11119.89593783406 10897.371694888818 8413.048210538693 8446.806975684329 7391.536390126082 11600.814305786393 10642.233568158967 7207.665589741217 7760.173811462703 7315.687996507255 1.5200068596614642 1.4895894548935895 1.1500009588374125 1.1546155303119963 1.0103679098473088 1.5857448146127877 1.4547139753964236 0.9852341424596551 1.060757896614462 1.0 12.836777832207684 -1.522878745280339 0.11679037691269235 0.9135318215755716 2.5706826574621413 0.29244173945515206 0.19348303914921283 156.23822570355927 1.2654685379838988 1.6419877858992846 41.9667541892735 0.029999999999999905 1.522878745280339 1.6571508358865699 LLPLEEHYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLPLEEHYR 9 0 A0A024R571;Q9H4M9;C9JIJ3;C9IZH1;C9JC03;Q9NZN3-2;Q9NZN3;Q9NZN4 A0A024R571;Q9NZN4 EHD1;EHD3;EHD2 EH domain-containing protein 1;EH domain-containing protein 3;EH domain-containing protein 2 0 ; 195.05 0.00035098 5015700.0 3759.04 4345.0 4075.7 3207.32 4761.0 6303.1 3490.1000000000004 3384.3 4953.4 5005.4 False True 4395.371227575754 4776.342884895373 4172.880145178326 3027.624258671736 3828.1162271244675 5972.55434002661 3159.4924618641558 3295.4657109622535 5025.834104087875 5912.839397275401 0.7433604960758977 0.8077917501186116 0.7057320290317985 0.512042363279281 0.6474243540063745 1.0100991991730275 0.5343443732498518 0.5573406428865264 0.8499865743696248 1.0 12.529635376257962 -8.519628588035635 6.683877900925489 0.9999507415158416 0.6927288438133385 0.33845843486963845 0.13958503367201944 0.1341637870787673 43.011724276718255 0.13939390569931515 0.03608170966478548 3.0225355109047295e-09 8.519628588035635 -0.3072218977025031 LLPLEEHYR ddPTM_PC-9_Lapatinib_30min_R1 1 LLPLEEHYR 9 0 A0A024R571;Q9H4M9;C9JIJ3;C9IZH1;C9JC03;Q9NZN3-2;Q9NZN3;Q9NZN4 A0A024R571;Q9NZN4 EHD1;EHD3;EHD2 EH domain-containing protein 1;EH domain-containing protein 3;EH domain-containing protein 2 0 159.58 0.00010896 2250800.0 3667.0 3264.0 2694.0 2410.3 2670.7 2219.6 2621.5 2330.4 2749.5 2745.2 False True 3614.7079075545616 3256.4424085395613 2472.509719140729 2587.561502525095 2513.614676798222 2124.672882140315 2757.2284429019887 2438.678891543463 2439.822356481434 3219.704162250929 1.12268324212355 1.0114104415925431 0.7679307149176623 0.8036643654602426 0.7806974026585496 0.6598969268825412 0.8563608033398886 0.7574232813484817 0.7577784273123181 1.0 11.652712419194215 -5.117099838020538 2.978955689382309 0.7852266999420748 1.112493958446044 0.6295320795524532 0.08385784791933726 0.15214834824044485 2.4764075352526973 0.020720208951411346 0.07904232432322839 7.636602089595945e-06 5.117099838020538 0.3272672585039692 LLPPVGTGRS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LLPPVGTGRSPR 12 1 Q9NWZ5-3;Q9NWZ5-2;Q9NWZ5;Q9NWZ5-4 Q9NWZ5-3 UCKL1 Uridine-cytidine kinase-like 1 1 LLPPVGTGRS(1)PR;LLPPVGT(0.003)GRS(0.997)PR;LLPPVGT(0.007)GRS(0.993)PR 126.09 0.00039374 17691700.0 81350.0 64442.0 86934.0 101960.0 102278.0 107250.0 104278.0 107258.0 103451.0 76973.0 True False 95120.94826426082 70839.37587765881 89006.8362590309 96247.51175878018 82237.36010876641 101625.62119716556 94400.03293265837 104442.59114924492 104963.7751649359 90927.59558206721 1.0461174922238967 0.7790745529361582 0.9788759472771639 1.0585071687275778 0.9044268638396209 1.1176543330615487 1.0381890374243659 1.1486346964379992 1.1543665538829766 1.0 16.472430583402513 -6.593934842087573 0.9116006974744798 1.1086681553713538 0.9267903760323711 0.32429798691991674 0.09006929565111813 0.603042337003732 1.0961991982249728 0.04988120202761529 0.05518821586341458 2.547212386364511e-07 6.593934842087573 -0.18187777933898264 LLPSAPQTLPDGPLAS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 3 LLPSAPQTLPDGPLASPAR 19 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0;X6RGP5;A0A0C4DH09 O15027 SEC16A Protein transport protein Sec16A 1 LLPS(0.029)APQT(0.06)LPDGPLAS(0.911)PAR;LLPSAPQTLPDGPLAS(1)PAR;LLPSAPQTLPDGPLAS(1)PAR 258.83 1.0123999999999997e-65 139227000.0 109119.8 149093.0 176249.0 231881.0 196539.0 179343.0 169070.0 249759.0 176366.0 198092.0 True False 143817.6265671612 197284.39657747763 173911.82310094914 178424.41797573754 169252.95236008498 168128.6538589249 184116.90246801128 211164.48544085928 185688.34670167492 191156.85937451184 0.7523539936665089 1.032055021321316 0.9097859405621618 0.9333927046069057 0.8854139627209869 0.8795324133753923 0.9631718321302404 1.1046660116294795 0.971392537569771 1.0 17.54439744446571 -7.531049992450701 8.719388431999255 1.0297988112663896 0.9074735226191802 0.38339763223973 0.0717170282803742 0.1444644366688727 97.04807984681737 0.0312713025456924 0.018601307347073957 2.9440827154204254e-08 7.531049992450701 -0.12232528864720937 LLPSAPQTLPDGPLAS(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 LLPSAPQTLPDGPLASPAR 19 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0;X6RGP5;A0A0C4DH09 O15027 SEC16A Protein transport protein Sec16A 1 LLPSAPQTLPDGPLAS(1)PAR;LLPS(0.006)APQT(0.001)LPDGPLAS(0.993)PAR;LLPSAPQTLPDGPLAS(1)PAR;LLPSAPQTLPDGPLAS(1)PAR;LLPSAPQT(0.001)LPDGPLAS(0.999)PAR;LLPSAPQTLPDGPLAS(1)PAR;LLPSAPQTLPDGPLAS(1)PAR 252.41 2.9820999999999992e-55 106471300.0 40562.5 54863.8 74193.2 69562.5 99662.8 97750.8 109319.09999999999 99561.2 94096.3 89936.70000000001 True False 47428.93010410681 60310.31548177738 75962.24726727804 65665.1386496679 80134.58977539602 92624.57596755128 98963.60344625456 96947.82399381131 95472.28037478973 106241.51177147446 0.4464255949795449 0.5676718495074213 0.7149959182684907 0.6180742118101035 0.7542681616557336 0.8718303648275147 0.9314965666068958 0.9125230089190196 0.8986344300159306 1.0 16.696988055316474 -4.974971279713182 0.3176454254136568 1.0043143677838853 0.09247370450644488 0.9263683810422129 0.046856380533508823 1.7132582921725203 0.15447199658741445 0.055320365356916625 0.6008927191093623 1.0593237769002766e-05 4.974971279713182 -0.9118406632774404 down LLPSAPQTLPDGPLAS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 2 LLPSAPQTLPDGPLASPAR 19 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0;X6RGP5;A0A0C4DH09 O15027 SEC16A Protein transport protein Sec16A 1 LLPSAPQTLPDGPLAS(1)PAR;LLPSAPQTLPDGPLAS(1)PAR 282.91 7.462499999999999e-106 63775000.0 44231.0 58018.0 76414.0 60968.0 77448.0 103506.0 99184.0 89492.0 107198.0 79069.0 True False 43600.257829027985 57883.66288561528 70131.53588656991 65451.790103285886 72892.66090862639 99079.28966427075 104319.26220896069 93650.12502660802 95124.23239501615 92735.9712971803 0.47015475461304285 0.6241770272737228 0.7562495427133388 0.7057864298799446 0.7860235881396623 1.0684019186768718 1.1249061259590494 1.009857595889067 1.0257533410652753 1.0 16.500841433026757 -6.2301695533370305 0.9058476022961851 1.0628079977637372 0.5581198735585171 0.8661862033988889 0.07591380639297786 0.22193851709008844 0.38704659560642063 0.04030293514846984 0.06790173161221141 5.886138091934698e-07 6.2301695533370305 -0.5046881242052201 LLPSVWS(ph)ESEDGAGSPPPYR ddPTM_PC-9_Lapatinib_30min_R1 1 LLPSVWSESEDGAGSPPPYR 20 0 K7EN65;K7EPZ6;A0A0A0MS90;Q9UIS9-4;Q9UIS9-11;Q9UIS9-7;K7EMA9;Q9UIS9-8;Q9UIS9-6;Q9UIS9-5;Q9UIS9-10;Q9UIS9-2;Q9UIS9;Q9UIS9-9;Q9UIS9-12 K7EN65 MBD1 Methyl-CpG-binding domain protein 1 1 LLPS(0.001)VWS(0.571)ES(0.427)EDGAGSPPPYR 104.76 0.0019027999999999998 0.0 4047.0 3110.6 4146.1 2922.2 2586.4 4382.2 2301.7 3538.3 3376.0 3177.0 True False 3989.289037871096 3103.397596814695 3805.223662408827 3137.108336173436 2434.2730370580466 4194.783521407139 2420.8707636954045 3702.702335199208 2995.759329143961 3726.1402169135968 1.0706223613816306 0.8328719307791572 1.0212239585446239 0.8419190243924684 0.6532961443609822 1.1257717845308906 0.6496993196087072 0.9937098766149486 0.8039845939091852 1.0 11.863466249451486 -3.060588635989119 1.9351408284692302 0.8751987945544027 132.3291959001066 0.11999324952823054 0.1495560594059681 2096.093312938883 14.438005943583534 0.03714869395900613 1219736.9724419056 0.0008697838990944011 3.060588635989119 131.45399710555222 LLPYPTLASPAS(ph)D ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLPYPTLASPASD 13 0 P0C1Z6-2;P0C1Z6 P0C1Z6-2 TFPT TCF3 fusion partner 1 LLPYPTLASPAS(1)D 107.03 0.0018802 0.0 1525.2 1069.3 2751.4 3256.1 3666.5 2741.0 1366.1 3339.3 961.25 2660.7 True False 1783.386235926871 1175.4530372424904 2817.0038107426058 3073.6712734186303 2948.0756451904763 2597.257134745272 1236.6931182924902 3251.6469132808124 975.3064627436642 3143.063847910389 0.5674037570418826 0.3739831877815558 0.896260447466074 0.9779219965455385 0.9379623793358358 0.826345648839432 0.3934673866439856 1.0345468850219548 0.3103043749467831 1.0 11.617955863871005 -5.261108989441694 24.999998044035877 0.79645256164925 0.4706934595960394 0.22733393899710208 0.24070204980363233 40.86121077234143 3091571.869082987 0.060587470678329675 0.14140488854712227 5.4813938798801215e-06 5.261108989441694 -0.3257591020532106 LLPYPTLASPAS(ph)D ddPTM_PC-9_Lapatinib_30min_R1 1 LLPYPTLASPASD 13 0 P0C1Z6-2;P0C1Z6 P0C1Z6-2 TFPT TCF3 fusion partner 1 LLPYPTLAS(0.002)PAS(0.998)D 105.2 0.0025346 0.0 1075.7 1058.6 1242.1 648.22 2166.2 511.01 1083.0 763.1 779.47 830.11 True False 1060.3603207407798 1056.1488767401897 1139.9793326446556 695.8922611985302 2038.7883749130606 489.1552935224912 1139.0724408403016 798.5564118335119 691.6778804170152 973.5934074479524 1.0891202761122496 1.0847946059008733 1.1708987796382528 0.7147668173130395 2.094086052058701 0.502422561390075 1.169967290376497 0.820215508573277 0.7104381306669765 1.0 9.927175588851071 LLQAQGVEVPSKDS(ph)LPK ddPTM_PC-9_AZD4547_30min_R2 1 LLQAQGVEVPSKDSLPK 17 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 LLQAQGVEVPS(0.339)KDS(0.661)LPK 55.755 0.024144 7660100.0 18586.0 23197.0 33604.0 45233.0 45587.0 30372.0 25464.0 37727.0 31979.0 38132.0 True False 24495.961387184183 30694.97660794105 33158.38900353647 34805.23069288358 39258.03193889866 28472.834038703815 27730.246669695596 31897.159030214272 33669.34465357757 36797.01028647747 0.665705208017571 0.8341703950666108 0.9011163881355286 0.9458711569747871 1.066881021943394 0.7737811799663327 0.7536005358534844 0.8668410499082356 0.9150021806513645 1.0 15.167300933329267 -1.5228787788175349 0.023895618658718316 1.5210967439689922 4.715809307657143e-08 0.1782686822880697 0.1034341935506106 5350.809920059198 9.873492824912702 219.90210098694007 444.9880407352378 0.02999999768333257 1.5228787788175349 -1.5210966968108992 LLQAQGVEVPSKDS(ph)LPK ddPTM_PC-9_Lapatinib_30min_R1 2 LLQAQGVEVPSKDSLPK 17 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 LLQAQGVEVPS(0.089)KDS(0.911)LPK;LLQAQGVEVPS(0.125)KDS(0.875)LPK 65.855 0.0098711 9942800.0 89113.0 76106.0 71908.0 79957.0 71531.0 68878.0 53991.0 53654.0 69382.0 63554.0 True False 87842.23227867734 75929.78123293855 65996.0018129071 85837.30450873292 67323.68721535684 65932.24850246016 56786.38980000807 56146.96071355692 61567.46853514993 74539.224219618 1.178469902233811 1.0186553727635197 0.8853862178449878 1.151572281673162 0.9031981204553227 0.8845309190259514 0.7618323157307887 0.753253891509909 0.8259740986001027 1.0 16.18571218358624 -6.575357854738698 2.506250192499869 0.8209750401809857 1.0434683024003526 0.48782911777924554 0.10078205325761128 0.2392869487888322 3.0477033041585972 0.0357240567840416 0.037017736539639086 2.658533549347653e-07 6.575357854738698 0.22249326221936694 LLQDFFNGK ddPTM_PC-9_Lapatinib_30min_R1 2 LLQDFFNGK 9 0 P11142;E9PKE3;P11142-2;E9PN89;E9PNE6;A8K7Q2;P54652;P17066 P11142;P17066 HSPA8;HSPA2;HSPA6 Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2;Heat shock 70 kDa protein 6 0 ; 125.16 0.0066139 44978000.0 114908.0 109757.0 103727.0 106660.0 106258.0 93104.0 128491.0 99555.0 106164.0 100783.0 False True 113269.39084845381 109502.86440994992 95198.96645779916 114504.1322073296 100008.11335126581 89122.1589560245 135143.63526870843 104180.6887433957 94206.69236351876 118203.20726509388 0.9582598769458512 0.9263950356640346 0.8053839541282226 0.9687057978937207 0.846069372102383 0.7539741181146683 1.1433161450993654 0.8813693905085846 0.7969893080163364 1.0 16.850909655829334 LLQDFFNGR ddPTM_PC-9_Lapatinib_30min_R1 1 LLQDFFNGR 9 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 91.265 0.036557 1888500.0 12344.0 10216.0 13575.0 10007.0 10707.0 12716.0 12163.0 9943.7 12318.0 10602.0 False True 12167.972296387636 10192.345479669166 12458.91590101538 10742.948162373405 10077.235310771925 12172.166322443793 12792.74062598393 10405.720603261561 10930.617125709512 12434.541573722987 0.9785621950149997 0.8196800355879551 1.0019602111704626 0.8639601306312487 0.81042274466052 0.978899483368679 1.028806775878083 0.8368399061249845 0.8790526824735052 1.0 13.602065700010765 LLQLVEDR ddPTM_PC-9_AZD4547_30min_R2 2 LLQLVEDR 8 0 P17844-2;P17844;J3KTA4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 ; 107.47 0.017553 6105000.0 23794.1 21641.1 30324.0 35161.0 36415.0 31710.0 27353.0 30920.0 23876.0 28266.0 False True 31360.128851974565 28636.16236022387 29921.883946650396 27055.17468203479 31359.40581865433 29727.16868718879 29787.364010217676 26142.024470915396 25138.03661617993 27276.41594350079 1.1497158907142568 1.0498506262530825 1.0969873757838755 0.9918889174470624 1.1496893830777062 1.08984878177413 1.0920556451374681 0.9584112709332808 0.9216033612425397 1.0 14.735366469650842 -7.764140868455047 23.01570886431508 0.9550053524392549 1.0860913650586135 0.6156271831797715 0.04647634556240825 16.509966427654298 140642.6645921763 0.023257552631855034 0.011989283868351902 1.721310157501496e-08 7.764140868455047 0.1310860126193586 LLQLVEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLQLVEDR 8 0 P17844-2;P17844;J3KTA4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 100.15 0.022951 860380.0 2985.8 3664.5 5686.4 6873.5 5187.3 5133.3 5564.7 4859.1 5815.9 4172.7 False True 3491.236967761902 4028.287342163199 5821.985341792093 6488.40007918767 4170.885802344622 4864.100711341811 5037.571331060845 4731.553773642017 5900.9465348981785 4929.177478924974 0.7082798261350739 0.8172331711297492 1.1811271488365713 1.3163251083835499 0.8461626346743492 0.9867976416224811 1.0219902514363333 0.9599073666696097 1.1971462906596624 1.0 12.267131211979866 -5.093477994942113 4.892477690888667 1.0584344938878572 0.7311955939808532 0.47274071484960944 0.12908894425174894 0.18406126607482745 7.046243034361687 0.034747693313497495 0.10205305570148476 8.063470567302474e-06 5.093477994942113 -0.32723889990700394 LLQLVEDR ddPTM_PC-9_Lapatinib_30min_R1 4 LLQLVEDR 8 0 P17844-2;P17844;J3KTA4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 ;;; 132.76 0.01763 13541000.0 52377.6 49846.5 54292.9 53080.9 58492.299999999996 53557.700000000004 45938.700000000004 44837.5 52837.5 40494.1 False True 51630.68581912452 49731.08349180983 49829.147338654686 56984.646458691575 55051.89791428641 51267.162020096584 48317.18110621456 46920.81393734128 46886.38434645852 47493.451230003404 1.0871116855476586 1.0471145432444975 1.0491793299530892 1.19984218840454 1.1591471347845121 1.0794574976625237 1.01734407281168 0.9879428157391862 0.987217882301184 1.0 15.535440976585837 -7.265896782819094 2.8744238622272147 0.9927807114615422 1.1075198757079463 0.5920801840734573 0.0436326521681057 0.22152636342504375 3.6848046073855194 0.022512031139834538 0.015227250714784432 5.4212972107940983e-08 7.265896782819094 0.11473916424640407 LLQLVEDRGS(ph)GR ddPTM_PC-9_AZD4547_30min_R2 1 LLQLVEDRGSGR 12 1 P17844-2;P17844;J3KTA4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 1 LLQLVEDRGS(1)GR 61.648999999999994 0.025925999999999998 2396300.0 4430.2 4801.2 6560.9 9382.8 7557.3 5580.9 5150.9 7302.1 6358.3 7126.8 True False 5838.911446115535 6353.094007416758 6473.898179184098 7219.740422814933 6508.09934349352 5231.925440754711 5609.320121384504 6173.728230565048 6694.386757273278 6877.292901229094 0.8490130535333195 0.9237783090903905 0.9413439666103355 1.049793941672113 0.9463170228405434 0.7607536156878928 0.8156290857383752 0.8976974398548145 0.9734043399659293 1.0 12.747625075384109 -3.4715373929526394 15.973422339745225 0.9113473807354334 0.34653218909437533 0.0 0.08310677808794875 0.0 0.0 0.02059023400100727 0.0 0.00033764677584931864 3.4715373929526394 -0.5648151916410581 LLQNGNS(ph)PAEVAK ddPTM_PC-9_Lapatinib_30min_R1 1 LLQNGNSPAEVAK 13 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 LLQNGNS(1)PAEVAK 136.39 8.1358e-05 0.0 30175.0 28423.0 24503.0 19842.0 28048.0 19688.0 19540.0 19501.0 19552.0 16175.0 True False 29744.69896658271 28357.18828980393 22488.45792431525 21301.246870971634 26398.271784489676 18845.9901349696 20551.68559004572 20407.08765190058 17349.847868312423 18970.82719816728 1.567917869678148 1.4947786932845732 1.1854231599604577 1.1228422803318503 1.3915192789822017 0.9934195245208001 1.083331020590982 1.0757088997084983 0.9145541038921352 1.0 14.211494966505226 -1.5228787452803385 0.2935137030353689 0.9727212796176659 6.184270394382985 0.7554604222084815 0.10553010256232645 26.08502710888286 0.37080760125948115 0.11171686885439285 70.84516767653155 0.029999999999999933 1.5228787452803385 5.211549114765319 LLQPGGGPDVGTGAPRPGCS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LLQPGGGPDVGTGAPRPGCSPR 22 1 Q9NXH8 Q9NXH8 TOR4A Torsin-4A 1 LLQPGGGPDVGT(0.045)GAPRPGCS(0.955)PR;LLQPGGGPDVGT(0.002)GAPRPGCS(0.998)PR;LLQPGGGPDVGT(0.022)GAPRPGCS(0.978)PR 66.633 0.0012684 28574400.0 94185.0 93961.0 97035.0 108446.0 143453.0 149433.0 130577.0 115444.0 130536.0 94764.0 True False 110128.66026145578 103288.82711338434 99348.68240728693 102370.12220667559 115344.41443597715 141596.47041823796 118207.80126438658 112413.71732302898 132444.84205015 111943.96304858889 0.983783825963485 0.9226833167283186 0.8874858429316549 0.9144764882251148 1.0303763713092084 1.2648870610090739 1.0559551229491393 1.004196334144756 1.1831351905297722 1.0 16.772417202585316 -6.436250805253871 4.531467054018628 1.1034992702655442 0.9257901707528216 0.5240026758933534 0.07802250525284765 0.18042020786304191 6.499958818179236 0.025059878868675098 0.028164516511450133 3.6622601788062105e-07 6.436250805253871 -0.17770909951272262 LLQPGGGPDVGTGAPRPGCS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 LLQPGGGPDVGTGAPRPGCSPR 22 1 Q9NXH8 Q9NXH8 TOR4A Torsin-4A 1 LLQPGGGPDVGT(0.052)GAPRPGCS(0.948)PR;LLQPGGGPDVGT(0.001)GAPRPGCS(0.999)PR 93.179 8.9516e-05 30314000.0 105633.0 101333.0 72479.0 83036.0 65970.0 98442.0 76196.0 64827.0 111544.0 61970.0 True False 104126.65404928046 101098.36966438104 66520.05639703081 89142.74443997587 62089.77430201016 94231.86513951028 80141.05605010873 67839.09908259883 98980.74010960716 72681.43193016545 1.432644504711032 1.3909793324039001 0.9152276534802634 1.226485803494171 0.854272854195662 1.2965053471985961 1.1026345233141626 0.9333759294640853 1.3618435614299798 1.0 16.149299222596966 -5.167509895084835 7.196761601324101 1.0890488559248117 1.4187832074216609 0.4000387917719137 0.1595642193189348 0.24415998863042843 16.201569854616853 0.037772780038924335 0.10169539233776347 6.799705521908866e-06 5.167509895084835 0.32973435149684915 LLQRS(ph)RS(ph)S(ph)LPVDDT(ph)T(ph)KTIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLQRSRSSLPVDDTTKTIAK 20 3 E9PIS7;Q9Y6K8-2;Q9Y6K8-3;Q9Y6K8 E9PIS7 AK5 Adenylate kinase isoenzyme 5 5 LLQRS(0.999)RS(0.999)S(0.999)LPVDDT(0.965)T(0.573)KT(0.463)IAK 45.577 0.042851 0.0 10109.0 7516.1 4736.5 5085.8 5033.1 3026.3 7244.6 5936.2 3545.8 4506.9 True False 11820.25403814892 8262.248735825575 4849.436123276279 4800.85911438607 4046.90018541066 2867.5955005033297 6558.339041638076 5780.381039923803 3597.6506170054467 5323.965293399229 2.220197425554959 1.5518975576473601 0.9108692217225229 0.9017450058020255 0.7601289569689902 0.5386202468409473 1.2318523281451987 1.0857285352874948 0.67574644437782 1.0 12.378285451102721 -4.936038609103293 1.9104941502758712 0.8783203934099961 2.414246669621934 0.8341524470421825 0.18974462208653492 0.2242081109082194 1.1197736674639989 0.054862396907198574 0.5548531500638931 1.1586743445630391e-05 4.936038609103293 1.5359262762119377 up LLQS(ph)PLCAGCSSDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLQSPLCAGCSSDK 14 0 Q9UJX6-2;Q9UJX6 Q9UJX6-2 ANAPC2 Anaphase-promoting complex subunit 2 1 LLQS(1)PLCAGCSSDK 127.18 0.00061163 0.0 12001.0 9653.8 15194.0 13424.0 13355.0 12064.0 12280.0 9183.5 10475.0 8691.2 True False 14032.532269445566 10612.165464258453 15556.282583565888 12671.89680119521 10738.183619669662 11431.34260254176 11116.749500499074 8942.442855722555 10628.17705824696 10266.84576049865 1.3667812487682702 1.0336344493542904 1.5151958981811309 1.2342541318727036 1.04590873089615 1.113423038507452 1.0827813877627732 0.8710019673353142 1.0351939929923286 1.0 13.325705396196167 -6.233603410682941 3.713536355617094 1.0229459459648742 1.291134323619415 0.5152348174771384 0.12593097446139817 0.19972671260190983 6.005987721081631 0.03907961116182248 0.04937356809927866 5.839781383941937e-07 6.233603410682941 0.26818837765454084 LLQS(ph)PLCAGCSSDK ddPTM_PC-9_Lapatinib_30min_R1 1 LLQSPLCAGCSSDK 14 0 Q9UJX6-2;Q9UJX6 Q9UJX6-2 ANAPC2 Anaphase-promoting complex subunit 2 1 LLQS(1)PLCAGCSSDK 126.07 3.3030999999999996e-05 10692000.0 51404.0 73250.0 68676.0 54958.0 73999.0 67798.0 65926.0 71576.0 72167.0 50385.0 True False 50670.9695336609 73080.39412546661 63029.724377026214 58999.79465451361 69646.5243076316 64898.43758485725 69339.32570160467 74901.68226103467 64038.79250779986 59093.98011620762 0.8574641517463714 1.2366808595690268 1.06660144151873 0.9984061750197093 1.1785722364726918 1.0982241754106803 1.1733737610032309 1.2675010570237677 1.0836770916744536 1.0 15.85072355058101 -6.271693336673809 24.72590825928465 1.147157198478688 1.0557671547775105 0.13681277108020728 0.10940648140081982 1217.653823901527 2936187.330448779 0.03270405900168734 0.03749394439403896 5.349419584280966e-07 6.271693336673809 -0.09139004370117743 LLQTCFS(ph)SPADDSMDR ddPTM_PC-9_AZD4547_30min_R2 3 LLQTCFSSPADDSMDR 16 0 Q9NZL4-2;Q9NZL4;Q9NZL4-3 Q9NZL4-2 HSPBP1 Hsp70-binding protein 1 1 LLQT(0.008)CFS(0.506)S(0.277)PADDS(0.209)MDR;LLQT(0.008)CFS(0.586)S(0.404)PADDS(0.002)MDR;LLQT(0.038)CFS(0.623)S(0.338)PADDSMDR 152.94 3.0726e-06 31698700.0 78818.0 66859.0 96211.0 141411.0 116445.0 101609.0 91911.0 124422.0 93767.0 97770.0 True False 103880.48448375541 88469.8642509949 94935.17927684926 108810.87872817085 100278.62173700958 95255.37316734655 100090.90094480026 105195.43883312521 98723.33219087558 94347.10205887178 1.1010458426050531 0.9377062180011684 1.0062331243370943 1.1533038784834515 1.0628691242094175 1.0096269105108073 1.0608794415576686 1.1149832537249968 1.046384361962417 1.0 16.525690584608846 LLQTCFS(ph)SPADDSMDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LLQTCFSSPADDSMDR 16 0 Q9NZL4-2;Q9NZL4;Q9NZL4-3 Q9NZL4-2 HSPBP1 Hsp70-binding protein 1 1 LLQT(0.139)CFS(0.52)S(0.341)PADDSMDR;LLQT(0.002)CFS(0.499)S(0.499)PADDSMDR;LLQT(0.048)CFS(0.591)S(0.361)PADDSMDR 105.39 0.0010009 13511400.0 34084.5 36178.4 40523.5 47116.0 44600.4 41132.8 42477.1 49408.0 39931.0 25231.800000000003 True False 39854.33265043892 39769.952457283965 41489.733926229586 44476.243272132975 35861.27178665031 38975.723557844 38453.361580427445 48111.092352103224 40514.91533296983 29806.125605181103 1.3371188586654539 1.3342878904855344 1.3919868176029413 1.4921846556401082 1.2031510657130378 1.3076413913745628 1.2901160684145818 1.6141343893330513 1.3592815070848139 1.0 14.863321236144538 -10.560823782834222 4.026042774746167 0.9999502931255212 1.3712708887309297 0.515869343875557 0.10752158382864148 78505212.05131002 149349226.0560244 52595.03874615835 0.027692407811063784 2.7490093511801482e-11 10.560823782834222 0.37132059560540853 LLQTCFS(ph)SPADDSMDR ddPTM_PC-9_Lapatinib_30min_R1 3 LLQTCFSSPADDSMDR 16 0 Q9NZL4-2;Q9NZL4;Q9NZL4-3 Q9NZL4-2 HSPBP1 Hsp70-binding protein 1 1 LLQTCFS(0.653)S(0.345)PADDS(0.002)MDR;LLQT(0.021)CFS(0.658)S(0.321)PADDS(0.001)MDR;LLQTCFS(0.5)S(0.5)PADDSMDR 136.63 9.5757e-06 13680000.0 70991.0 71351.4 80545.4 78495.8 80809.3 74840.0 68860.2 64304.5 85428.2 71144.5 True False 69978.65532184506 71186.19021711688 73923.26812623523 84268.6429863126 76056.25585119649 71639.26766056102 72425.44422045378 67292.3218251186 75806.37651717306 83441.73203091243 0.838652957202761 0.8531245515223093 0.8859268177564803 1.0099100406388235 0.9114894190238061 0.8585544177585026 0.8679762806652014 0.8064588328558304 0.9084947624180342 1.0 16.348481484272824 -5.280897439947384 4.2836159677072665 0.9004428074614143 0.8444140383987606 0.1437757769069743 0.05821708925603876 0.446501449517482 20.322873346400247 0.01627179917857294 0.03995014858323964 5.237241011309737e-06 5.280897439947384 -0.05602876906265364 LLQTCFSS(ph)PADDSMDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLQTCFSSPADDSMDR 16 0 Q9NZL4-2;Q9NZL4;Q9NZL4-3 Q9NZL4-2 HSPBP1 Hsp70-binding protein 1 1 LLQT(0.061)CFS(0.209)S(0.73)PADDS(0.001)MDR;LLQT(0.005)CFS(0.186)S(0.809)PADDSMDR 111.78 0.00037072 16758500.0 149044.0 148611.0 159985.0 164960.0 185674.0 155459.0 169402.0 157147.0 141023.0 121557.0 True False 174274.20544681617 163364.11794411647 163799.64914649114 155717.82600753548 149292.51257196153 147306.45637007148 153355.01619572833 153022.05776100964 143085.19458569557 143594.32185531754 1.2136566627085088 1.1376781186983045 1.140711185721759 1.0844288548152574 1.0396825629524917 1.025851541111035 1.0679740968465692 1.0656553531078428 0.9964544052783998 1.0 17.131639176291806 -1.5228787452807455 0.3056673263271568 1.0124971683085797 2.8172626121978404 0.8756393913137979 0.02315322993919898 19.155535794914623 0.27334687783846917 0.02453324720375796 19.02467108560166 0.02999999999997182 1.5228787452807455 1.8047654438892606 LLQTCFSS(ph)PADDSMDR ddPTM_PC-9_Lapatinib_30min_R1 3 LLQTCFSSPADDSMDR 16 0 Q9NZL4-2;Q9NZL4;Q9NZL4-3 Q9NZL4-2 HSPBP1 Hsp70-binding protein 1 1 LLQT(0.007)CFS(0.474)S(0.519)PADDSMDR;LLQT(0.007)CFS(0.239)S(0.754)PADDSMDR;LLQT(0.003)CFS(0.244)S(0.744)PADDS(0.009)MDR 124.04 3.2384e-05 14280100.0 35445.5 39943.3 47364.7 39375.8 39095.1 43985.3 35101.9 38807.4 47020.0 35851.6 True False 34940.04067009141 39850.81374295904 43470.55719902931 42271.62768581818 36795.603081923924 42104.151253742275 36919.30462708421 40610.533477378915 41724.11245744936 42048.50129074583 0.8309461597334298 0.947734461863675 1.0338194195900259 1.0053064054181036 0.8750752572011887 1.001323470784646 0.8780171348273365 0.9658021625212267 0.9922853651536003 1.0 15.359766759841024 LLQTT(ph)NNSPMNSKPQQIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLQTTNNSPMNSKPQQIK 18 1 O00178;B0QY59 O00178 GTPBP1 GTP-binding protein 1 1 LLQT(0.189)T(0.583)NNS(0.228)PMNSKPQQIK;LLQT(0.13)T(0.446)NNS(0.424)PMNSKPQQIK 69.37899999999999 0.0071519999999999995 64379000.0 235980.0 231330.0 225040.0 253930.0 272670.0 239880.0 278140.0 231130.0 232300.0 190215.0 True False 275926.7531825481 254294.91359329046 230405.8070689522 239703.12535216816 219242.27087797257 227300.2705153943 251792.5656407828 225063.08240247786 235696.94803157638 224699.4737588888 1.2279813057267244 1.1317112111537861 1.025395401309157 1.0667720815820818 0.9757133259387513 1.011574556508736 1.120574790090367 1.0016181998004108 1.0489430352849347 1.0 17.777637220199267 -4.93624861192721 1.979036550895242 1.0320212499558203 1.2549170909060197 0.7220818021436821 0.039040565359906486 0.28220551450098386 1.5487930114625694 0.010643613233923033 0.10354665458923808 1.158114203750344e-05 4.93624861192721 0.22289584095019932 LLQTT(ph)NNSPMNSKPQQIK ddPTM_PC-9_Lapatinib_30min_R1 1 LLQTTNNSPMNSKPQQIK 18 1 O00178;B0QY59 O00178 GTPBP1 GTP-binding protein 1 1 LLQT(0.167)T(0.487)NNS(0.321)PMNS(0.026)KPQQIK 60.621 0.023356000000000002 20201000.0 123350.0 87220.0 106420.0 81412.0 112080.0 87724.0 84408.0 97628.0 98477.0 77045.0 True False 121591.0063803801 87018.047448781 97670.55839307944 87399.31006247044 105487.67475775821 83972.24901463196 88778.23322848412 102164.1532885362 87385.48325121742 90362.12559399041 1.3455970140267106 0.9629924802761411 1.0808793811682433 0.9672117547916889 1.1673881514444338 0.9292858978542731 0.9824717230245011 1.1306081238900239 0.9670587392316615 1.0 16.46343058728621 -4.7545392644642845 24.986231606801816 1.0256729263525117 1.3455975664188289 0.6253074046646455 0.07532626041893185 150.79369062108597 545995.6003513046 0.017642472876602915 0.1705439699234939 1.759789554439936e-05 4.7545392644642845 0.31992464006631716 LLQTTNNS(ph)PMNSKPQQIK ddPTM_PC-9_AZD4547_30min_R2 3 LLQTTNNSPMNSKPQQIK 18 1 O00178;B0QY59 O00178 GTPBP1 GTP-binding protein 1 1 LLQT(0.08)T(0.292)NNS(0.627)PMNSKPQQIK;LLQT(0.07)T(0.231)NNS(0.694)PMNS(0.004)KPQQIK;LLQT(0.064)T(0.342)NNS(0.594)PMNSKPQQIK 98.06200000000001 0.00034641 84970000.0 211085.0 182953.0 280633.0 305268.0 281571.0 268768.0 248875.0 285328.0 207331.0 247674.0 True False 278205.6391592473 242088.97940908867 276911.6230576554 234893.17894358508 242479.72691924573 251961.89447235374 271024.3928652402 241237.1137851665 218290.09338537444 239003.00864609831 1.164025677899302 1.0129118490201094 1.158611452744053 0.9828042762900996 1.0145467552598701 1.0542205970530028 1.1339790005177603 1.0093476025750634 0.9133361735567339 1.0 17.86666925386244 -1.5228787452815988 0.18875117904551889 0.9812929262915054 1.5947644720765417 0.2713643139981913 0.066957363337137 87.26443677637275 1.0154876955950483 0.14203603141507995 15.561758299397187 0.029999999999912874 1.5228787452815988 0.6134715457850363 LLQTTNNS(ph)PMNSKPQQIK ddPTM_PC-9_Lapatinib_30min_R1 1 LLQTTNNSPMNSKPQQIK 18 1 O00178;B0QY59 O00178 GTPBP1 GTP-binding protein 1 1 LLQT(0.007)T(0.089)NNS(0.904)PMNSKPQQIK 84.40299999999999 0.0029682 15008000.0 164990.0 129890.0 145410.0 111450.0 129000.0 135510.0 127230.0 129930.0 142640.0 99974.0 True False 162637.21234453973 129589.24768541791 133454.95109883227 119646.40478630128 121412.47362375821 129714.5531892385 133817.34685882897 135967.0221327851 126574.38113421034 117254.3726930184 1.387046031710368 1.1051975692598963 1.1381660916666052 1.020400365788877 1.0354622248641085 1.1062662330627266 1.1412567717979591 1.15959020555044 1.0794853806057407 1.0 16.839282199692626 -4.758110457861636 5.07288944325004 1.0913199602583534 1.4061154528650763 0.7552716112982918 0.05119732527573977 0.09096147072279169 6.291718159099121 0.013375027803190099 0.10238768212951038 1.7453781793757797e-05 4.758110457861636 0.3147954926067229 LLQYLYS(ph)LK ddPTM_PC-9_AZD4547_30min_R2 1 LLQYLYSLK 9 0 P49356;B4DL54;P49356-2 P49356 FNTB;CHURC1-FNTB Protein farnesyltransferase subunit beta 1 LLQY(0.007)LY(0.007)S(0.987)LK 74.533 0.02729 96429000.0 68553.0 51754.0 89347.0 110890.0 97341.0 78894.0 77099.0 91802.0 68241.0 82622.0 True False 90351.42800901938 68482.46839536916 88162.20040170729 85326.0237334215 83826.88237796597 73960.74570820143 83960.66163944609 77616.11030009635 71848.07994323726 79729.42892817962 1.1332255758461292 0.8589358950138506 1.1057673632796734 1.0701948437418674 1.0513919829211036 0.9276467510487924 1.0530698986327616 0.9734938697480581 0.901148809280424 1.0 16.282824715209784 -6.740832952600435 24.979546491569785 0.9745400980082093 1.0385247405229743 0.17556146940432837 0.07830200463279809 496.8902130088179 602339.4334705671 0.025431228151867078 0.025403585999683984 1.8162141185833032e-07 6.740832952600435 0.06398464251476499 LLQYLYS(ph)LK ddPTM_PC-9_Lapatinib_30min_R1 1 LLQYLYSLK 9 0 P49356;B4DL54;P49356-2 P49356 FNTB;CHURC1-FNTB Protein farnesyltransferase subunit beta 1 LLQY(0.001)LY(0.001)S(0.998)LK 72.434 0.032297 78585000.0 126760.0 116240.0 125080.0 139530.0 138520.0 119250.0 109830.0 110140.0 114410.0 96719.0 True False 124952.37915506272 115970.85342176443 114796.40522276238 149791.50165843483 130372.52594079828 114149.95548532724 115516.45999768283 115257.5064858381 101523.94100928928 113436.7502800334 1.1015158566038032 1.0223393488924468 1.0119860181058826 1.3204847748957458 1.1492970806987746 1.0062872499743971 1.0183336503603584 1.016050849493748 0.8949828054723377 1.0 16.79152858259554 -6.8320808228799805 5.753572240301232 0.9882210216066754 1.1204667974762954 0.38075533799153827 0.08559444844330709 0.2557773974220094 15.11979226448985 0.03304949818830922 0.029329289372764113 1.472038528275546e-07 6.8320808228799805 0.13224577586962005 LLREEFHT(ph)DVT(ph)FS(ph)VGCTLFK ddPTM_PC-9_AZD4547_30min_R2 1 LLREEFHTDVTFSVGCTLFK 20 1 A0A1B0GUL6;B4DKD6;Q5XKL5-2;Q5XKL5 A0A1B0GUL6 BTBD8 BTB/POZ domain-containing protein 8 3 LLREEFHT(1)DVT(0.998)FS(0.998)VGCT(0.004)LFK 48.848 0.024794 3892800.0 8381.3 8616.0 8917.0 15361.0 13023.0 12363.0 8553.4 13767.0 10830.0 12909.0 True False 11046.37905813014 11400.953504936844 8798.754753735706 11819.758775084214 11214.981243343002 11589.939655620155 9314.636029868605 11639.626484187982 11402.4516901168 12457.059839193798 0.8867565220626767 0.9152202567949369 0.7063267630819334 0.9488401699649515 0.9002911913497573 0.9303912644904047 0.7477395268313517 0.9343799126312362 0.9153405247553784 1.0 13.604675977931231 -8.484118350000712 1.6682612698538977 0.9963822668533885 0.8667490009351362 0.21843704814654474 0.07631141292385274 0.5715228282944145 3.5177306030766617 0.07166899618290652 0.020770012554652762 3.2800589573539244e-09 8.484118350000712 -0.1296332659182523 LLS(ph)DSLPPSTGTFQEAQSR ddPTM_PC-9_AZD4547_30min_R2 4 LLSDSLPPSTGTFQEAQSR 19 0 Q9Y490 Q9Y490 TLN1 Talin-1 1 LLS(0.832)DS(0.168)LPPSTGTFQEAQSR;LLS(0.992)DS(0.008)LPPSTGTFQEAQSR;LLS(0.708)DS(0.292)LPPSTGTFQEAQSR;LLS(0.687)DS(0.313)LPPSTGTFQEAQSR 180.02 6.602899999999999e-37 9668200.0 39304.7 41652.3 55107.6 70780.7 60123.6 56271.0 54178.6 57591.1 53796.4 55207.7 True False 51802.777011452585 55115.5914198794 54376.83721733379 54463.30316591397 51776.47594887948 52752.36547451278 59000.39044214453 48691.71880682195 56639.96787647272 53274.89522691605 0.9723675061359912 1.0345509115526776 1.020684076162406 1.0223070910592331 0.9718738202739904 0.9901918201776345 1.1074707925907998 0.9139711790971566 1.0631643222426561 1.0 15.701168230283711 LLS(ph)DSLPPSTGTFQEAQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLSDSLPPSTGTFQEAQSR 19 0 Q9Y490 Q9Y490 TLN1 Talin-1 1 LLS(0.949)DS(0.051)LPPSTGTFQEAQSR;LLS(1)DSLPPSTGTFQEAQSR 158.17 2.5758999999999997e-20 0.0 4279.1 7370.400000000001 5014.9 6421.3 7384.0 6276.08 6290.2 7326.2 4800.95 4269.48 True False 5003.467113922549 8102.084602723332 5134.474235114157 6061.535379135486 5937.158206487516 5946.951316392601 5694.3467188957065 7133.895012750539 4871.154811244937 5043.502926814917 0.9920619035076774 1.6064399526065063 1.0180373263621143 1.2018502749166597 1.1771894043961546 1.179131132208588 1.129045982826823 1.4144722658574425 0.9658276959345751 1.0 12.300210379448599 -8.298161021077284 24.82552512703846 0.982913596793987 1.2155459823445218 0.22731443437411536 0.17098992761641943 867.788776324029 586657.4016668925 0.15325841388021053 0.03957537378330086 5.033139631224719e-09 8.298161021077284 0.23263238555053478 LLS(ph)DSLPPSTGTFQEAQSR ddPTM_PC-9_Lapatinib_30min_R1 2 LLSDSLPPSTGTFQEAQSR 19 0 Q9Y490 Q9Y490 TLN1 Talin-1 1 LLS(0.999)DS(0.001)LPPSTGTFQEAQSR;LLS(0.756)DS(0.244)LPPSTGTFQEAQSR 151.39 6.4804e-05 3429900.0 10689.679999999998 13239.2 14989.9 15810.8 16223.0 16823.7 20273.1 19762.4 18841.7 16106.8 True False 10537.24320295277 13208.545445814027 13757.488284687319 16973.578975282646 15268.795035645173 16104.18956896017 21322.74192095987 20680.633250188177 16719.549334103012 18890.838919038048 0.5577964667484097 0.6992037517456439 0.7282624315229655 0.8985084806464999 0.8082645297587814 0.8524867338067494 1.1287345158330142 1.0947440364517844 0.8850612408352694 1.0 14.205399151019588 -5.389343072717532 0.4800647619235135 1.0347775278590834 0.4195180950804771 0.7436292694476143 0.08563166874550358 1.4498774560388425 0.3932179659755478 0.06669291968966919 0.4749970143485971 4.079969601167854e-06 5.389343072717532 -0.6152594327786063 LLS(ph)FSPEEFPTLK ddPTM_PC-9_AZD4547_30min_R2 1 LLSFSPEEFPTLK 13 0 Q5JSZ5;Q5JSZ5-5;A0A1W2PQP5 Q5JSZ5 PRRC2B Protein PRRC2B 1 LLS(0.981)FS(0.019)PEEFPTLK 242.4 2.6243999999999997e-27 9350100.0 40118.0 34718.0 54936.0 62903.0 63401.0 48112.0 46091.0 54211.0 48522.0 53571.0 True False 52874.689493761674 45939.914552506634 54207.51274545526 48401.68519166216 54598.865530921445 45103.54903431181 50193.00970990181 45833.935594851035 51086.7738603737 51695.495595743356 1.0228103799843524 0.8886637805304135 1.0485925731200214 0.9362843828824341 1.0561629190651798 0.8724850881983935 0.9709358452119131 0.8866137187903279 0.9882248592772989 1.0 15.657750958642998 -6.76540472098213 24.9998843670187 0.9382705236601027 0.9850601526505193 0.12441508930153744 0.0604628299653582 212.42366078984924 1339233.7174243298 0.0193903534647174 0.01773181886202391 1.7163082063242018e-07 6.76540472098213 0.04678962899041661 LLS(ph)FSPEEFPTLK ddPTM_PC-9_Lapatinib_30min_R1 2 LLSFSPEEFPTLK 13 0 Q5JSZ5;Q5JSZ5-5;A0A1W2PQP5 Q5JSZ5 PRRC2B Protein PRRC2B 1 LLS(0.934)FS(0.066)PEEFPTLK;LLS(0.994)FS(0.006)PEEFPTLK 259.27 4.0944e-44 17025100.0 106473.0 90946.0 106802.0 91730.0 97035.0 96927.0 89952.0 91757.0 98850.0 78020.0 True False 104954.67549524306 90735.42012470566 98021.15182764213 98476.13020230975 91327.59207815015 92781.65815787278 94609.27442148369 96020.36519539735 87716.47206335323 91505.65304488463 1.1469747715341863 0.991582673916319 1.0712032378978986 1.0761753719631508 0.9980540987271339 1.0139445495499853 1.0339172638337075 1.0493380681988924 0.958590744337153 1.0 16.481573252649916 LLS(ph)GDSTEK ddPTM_PC-9_Lapatinib_30min_R1 1 LLSGDSTEK 9 0 Q6P0Q8;Q6P0Q8-2;A0A669KBJ4;E7ERL6 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 LLS(0.997)GDS(0.002)TEK 73.95100000000001 0.028210000000000002 2591900.0 44761.0 44689.0 49705.0 49776.0 63320.0 67201.0 78591.0 74014.0 64064.0 66790.0 True False 44122.69993183794 44585.52536618396 45618.44676684855 53436.69308786834 59595.6420919098 64326.969883182166 82660.05743128357 77452.96064139128 56848.437696172565 78334.56250791931 0.5632596713280592 0.5691679884173291 0.5823540121544268 0.6821598458849644 0.7607834930575494 0.8211824745517531 1.055218217666397 0.988745684684983 0.7257133489502212 1.0 16.257361368508057 -6.4386662082065635 1.2114756170763408 0.9394336156467297 0.5670630713558585 0.7641460993485099 0.08585548193992544 0.22237184200441565 0.6786522753264738 0.038365610278585614 0.04701522581648211 3.641948429178855e-07 6.4386662082065635 -0.37237054429087113 LLS(ph)GDSTEKR ddPTM_PC-9_Lapatinib_30min_R1 1 LLSGDSTEKR 10 1 Q6P0Q8;Q6P0Q8-2;A0A669KBJ4;E7ERL6 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 LLS(0.998)GDS(0.001)T(0.001)EKR 69.01 0.039016 0.0 21088.0 20538.0 24287.0 20617.0 31923.0 38119.0 36185.0 37529.0 43862.0 28545.0 True False 20787.281252934423 20490.44552285097 22290.21661053115 22133.242956295842 30045.35190303277 36488.73922972906 38058.48224543521 39272.73434635028 38921.799672663605 33478.96521617833 0.6209057274831542 0.6120393922136277 0.6657976573230423 0.661108932530573 0.8974396821713502 1.0899004492557103 1.1367878905362307 1.1730569954226713 1.1625747516788567 1.0 15.030967316620533 -6.49440309240462 1.8018977163253345 1.134346969995256 0.6276214256580881 0.9567661062632256 0.04733900447828731 0.06089325612686735 0.39787012654103077 0.017227253120029717 0.01916362432096346 3.203294791631666e-07 6.49440309240462 -0.5067255443371679 LLS(ph)GSESSSK ddPTM_PC-9_AZD4547_30min_R2 2 LLSGSESSSK 10 0 G3XAI9;Q5BKY9-2;Q5BKY9 G3XAI9 FAM133B Protein FAM133B 1 LLS(0.988)GS(0.005)ES(0.006)S(0.001)SK;LLS(0.979)GS(0.019)ES(0.001)S(0.001)SK 110.08 0.0017916 28146000.0 88149.0 102240.0 113560.0 148944.0 127536.0 126647.0 102732.0 137089.0 101630.0 117428.0 True False 116178.54838689875 135287.0805878298 112054.12020121417 114607.26196186067 109829.82783160533 118727.74306926507 111874.9489817456 115905.04504182779 107001.95431824282 113316.88146230155 1.0252536681884352 1.19388284289166 0.9888563712238456 1.0113873633205164 0.9692274126705799 1.0477498280674413 0.98727521917345 1.0228400530099946 0.9442719649308422 1.0 16.790003278117027 -5.289893081256381 24.904133828426676 0.9983322938223714 1.1095682711700998 0.48840164969475186 0.046276892771514117 446.4686906777828 390771.6013028398 0.011048292627836506 0.02300682109160901 5.1298766062508825e-06 5.289893081256381 0.11123597734772839 LLS(ph)GSESSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLSGSESSSK 10 0 G3XAI9;Q5BKY9-2;Q5BKY9 G3XAI9 FAM133B Protein FAM133B 1 LLS(0.991)GS(0.009)ESSSK 89.54799999999999 0.0092789 7477900.0 31574.0 44276.0 38607.0 47211.0 40491.0 42597.0 53888.0 45726.0 41157.0 45494.0 True False 36918.8545850741 48671.42867010988 39527.53729786285 44565.92073012713 32557.07921707556 40363.13833226719 48783.3385246656 44525.74095070178 41758.84326360573 53741.70206969416 0.6869684651445614 0.9056547670743854 0.7355095907941681 0.8292614303940812 0.6058066261997875 0.751058056924264 0.907737132355831 0.8285137841923802 0.7770286696437595 1.0 15.713754393654922 -9.694641304169652 0.4282260441798826 1.0370822635134405 0.7645287474264963 0.3751309756695528 0.08728806484080326 6.253135491877106 1.3284129633914026 0.47444773084452846 0.055374833425142135 2.0200340769237686e-10 9.694641304169652 -0.2725535160869441 LLS(ph)GSESSSK ddPTM_PC-9_Lapatinib_30min_R1 2 LLSGSESSSK 10 0 G3XAI9;Q5BKY9-2;Q5BKY9 G3XAI9 FAM133B Protein FAM133B 1 LLS(0.954)GS(0.042)ES(0.004)SSK;LLS(1)GSESSSK 119.74 0.00076409 21765000.0 130807.0 139805.0 127495.0 111081.0 133109.0 149610.0 139897.0 122888.0 140458.0 133887.0 True False 128941.66819293403 139481.29011209347 117012.85324493246 119250.26729535323 125279.79032236285 143211.52905794382 147140.18213872184 128597.82510470024 124638.14095168919 157029.18955678644 0.8211318453395244 0.8882507163526617 0.7451662558738299 0.7594146517086161 0.7978121180906811 0.9120057835244335 0.9370244000750673 0.8189421690812168 0.7937259391294019 1.0 17.260673235557498 -6.750766785374997 24.93141100023457 0.8838163400163378 0.8015643369373169 0.31958725533461707 0.06505241129584398 292.7645103380908 683903.16532832 0.02248988221603281 0.02226629468619519 1.7751424703185538e-07 6.750766785374997 -0.08225200307902092 LLS(ph)LMVCNHEK ddPTM_PC-9_Lapatinib_30min_R1 1 LLSLMVCNHEK 11 0 H0Y465;P21359-2;P21359-6;P21359;P21359-4;J3KSB5 H0Y465;J3KSB5 NF1 Neurofibromin;Neurofibromin truncated 1 LLS(1)LMVCNHEK 82.645 0.012077 21805000.0 17023.0 27877.0 57259.0 58050.0 47829.0 39214.0 26855.0 25531.0 55682.0 32665.0 True False 16780.248898364134 27812.45251925776 52551.38604613181 62319.19064912323 45015.792255431974 37536.90863229876 28245.42049747581 26717.263465497854 49410.5068025456 38311.10172662345 0.43799964350028264 0.7259632656277831 1.3717012478816915 1.6266614072812189 1.1750064661844284 0.979791938643553 0.7372646367370658 0.6973765373844962 1.289717720861284 1.0 15.225474894026501 LLS(ph)PILARY(ph)GMDKQT(ph)GR ddPTM_PC-9_Lapatinib_30min_R1 1 LLSPILARYGMDKQTGR 17 2 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 3 LLS(1)PILARY(1)GMDKQT(1)GR 43.841 0.04067 119720000.0 17764.0 15024.0 109340.0 19778.0 46245.0 62772.0 30281.0 20972.0 102660.0 25855.0 True False 17510.682102481376 14989.212851071805 100350.48726460566 21232.540097473877 43524.96002116817 60087.38788867894 31848.80201392907 21946.435682050094 91097.34974227453 30324.002300378033 0.5774528681612413 0.4943019296263852 3.3092758096563872 0.7001892391100756 1.4353303231554486 1.9815124432941313 1.0502835904854164 0.7237315003691481 3.0041334530943122 1.0 14.888172559108744 LLS(ph)PLRDTPPPQSLMVK ddPTM_PC-9_AZD4547_30min_R2 2 LLSPLRDTPPPQSLMVK 17 1 A0A669KBI3;F5GXF9;P51825;P51825-3;P51825-2 A0A669KBI3 AFF1 AF4/FMR2 family member 1 1 LLS(1)PLRDTPPPQSLMVK;LLS(0.909)PLRDT(0.091)PPPQSLMVK 125.23 1.8352e-05 7667900.0 14470.0 15942.2 31361.9 38269.0 33774.0 23436.0 26149.6 35292.0 24077.9 28886.1 True False 19071.15900530264 21095.204383287397 30946.020714498587 29446.673300156093 29085.063081675995 21970.543215167352 28476.863741512392 29838.432329480802 25350.608637992915 27874.806431244557 0.6841718902100068 0.7567838878207247 1.1101788559798407 1.056390234414315 1.0434175804383299 0.7881863958180106 1.0215986185142796 1.0704444675904632 0.9094451902481269 1.0 14.766674166227121 -5.133483998243317 5.2890629739002675 0.9986445497402979 0.7023132061857805 0.6229408787944324 0.08755541330022137 0.1413085063124801 5.375697669916788 0.02331373004595343 0.06576664412871101 7.35387090612446e-06 5.133483998243317 -0.2963313435545174 LLS(ph)PLRDTPPPQSLMVK ddPTM_PC-9_Lapatinib_30min_R1 1 LLSPLRDTPPPQSLMVK 17 1 A0A669KBI3;F5GXF9;P51825;P51825-3;P51825-2 A0A669KBI3 AFF1 AF4/FMR2 family member 1 1 LLS(0.976)PLRDT(0.024)PPPQSLMVK 51.166000000000004 0.036000000000000004 2667300.0 13293.0 10243.0 10702.0 9668.7 11859.0 13124.0 11387.0 11029.0 9289.3 9579.7 True False 13103.439382362354 10219.282962828043 9822.122870914665 10379.76845183769 11161.476935691067 12562.71711353825 11976.563142981096 11541.447603343995 8243.041213334418 11235.538380852124 1.1662493543427837 0.909549913535429 0.8742013544854926 0.9238336517569236 0.993408286932892 1.1181232877053704 1.0659536496614923 1.0272269304881028 0.7336578750318195 1.0 13.455781636312564 -8.223075887925654 24.970407668579007 0.8668286733534423 1.0040236634838011 0.22539653939996396 0.10559400619203568 741.5932023015952 482696.8342722055 0.0733297024783043 0.027714678425295076 5.983070387071287e-09 8.223075887925654 0.13719499013035885 LLS(ph)PLSSAR ddPTM_PC-9_AZD4547_30min_R2 6 LLSPLSSAR 9 0 A0A087WZ13;Q8IY67-2;E9PAU2 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 LLS(0.992)PLS(0.001)S(0.007)AR;LLS(0.966)PLS(0.031)S(0.004)AR;LLS(1)PLSSAR;LLS(0.999)PLS(0.001)SAR;LLS(0.999)PLS(0.001)SAR;LLS(0.932)PLS(0.034)S(0.034)AR 156.16 8.6316e-05 413500000.0 193805.0 198685.0 318253.0 423119.0 340298.0 301832.0 260986.0 381660.0 265899.0 330773.0 True False 255430.95860557552 262906.04075306136 314032.7572771842 325575.4516733846 293053.49667105405 282958.39732549863 284213.24840312486 322683.2166743065 279953.87829643284 319192.7379494651 0.8002405074955545 0.8236592174433646 0.9838342792338283 1.0199964252474 0.9181082832700616 0.8864813126490894 0.8904126398017294 1.010935332511838 0.8770684448991298 1.0 18.28406830317917 -5.196170316181271 6.25774012082306 0.9458489477361058 0.8089563936919357 0.5297643433698809 0.05140803040101494 0.1864167554468734 14.053543012931478 0.013514704154710889 0.03658831514950163 6.365458393621066e-06 5.196170316181271 -0.1368925540441701 LLS(ph)PLSSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 LLSPLSSAR 9 0 A0A087WZ13;Q8IY67-2;E9PAU2 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 LLS(0.994)PLS(0.003)S(0.003)AR;LLS(0.974)PLS(0.023)S(0.002)AR;LLS(0.997)PLS(0.003)SAR;LLS(0.987)PLS(0.012)S(0.001)AR;LLS(0.87)PLS(0.129)SAR;LLS(1)PLSSAR;LLS(0.918)PLS(0.041)S(0.041)AR 156.16 8.6316e-05 356345800.0 273855.0 308783.0 456705.0 410263.0 495216.0 455720.0 444630.0 441568.0 415428.0 308483.0 True False 320213.2426172005 339436.93556424574 467594.5792633586 387277.2942005922 398181.9797378009 431821.2409507906 402511.42755756585 429977.30787996855 421502.84858743876 364408.5259499162 0.878720501345268 0.9314736384924689 1.2831603707527528 1.0627558539994726 1.0926801964905906 1.1849921453543035 1.104560949852437 1.1799320741992299 1.1566766927000207 1.0 18.47519718824683 -5.110577125724176 6.585937753436625 1.1360310743338393 0.8916650812284929 0.6116601969357954 0.07310928054520541 0.13142426838567203 6.690080717396778 0.017486820026876848 0.04769195629001287 7.752162616083747e-06 5.110577125724176 -0.24436599310534646 LLS(ph)PLSSAR ddPTM_PC-9_Lapatinib_30min_R1 6 LLSPLSSAR 9 0 A0A087WZ13;Q8IY67-2;E9PAU2 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 LLS(0.996)PLS(0.004)SAR;LLS(0.999)PLS(0.001)SAR;LLS(0.988)PLS(0.012)SAR;LLS(0.91)PLS(0.045)S(0.045)AR;LLS(0.999)PLS(0.001)SAR;LLS(0.985)PLS(0.014)S(0.001)AR 176.6 0.0015157 362056000.0 172613.0 163577.0 225809.0 167461.0 198857.0 199205.0 153847.0 179642.0 215819.0 160816.0 True False 170151.50696665279 163198.24750664062 207243.85566794703 179776.64057351954 187160.62222790412 190685.46651953575 161812.44488084747 187988.82313536308 191511.1915451779 188612.83132614903 0.9021205279105696 0.8652552764262281 1.0987791986939706 0.9531516986914323 0.9923005816304525 1.0109888345284566 0.8579079362900907 0.9966915920491809 1.0153667181530033 1.0 17.5250683002956 -5.202069457391367 24.999997509544205 0.9852360799922486 0.8836877125263392 0.35533958837367696 0.0572569902617522 290.947724066534 122513.37471998058 0.014504858000062048 0.03837623759356352 6.2795792049585714e-06 5.202069457391367 -0.10154836746590945 LLS(ph)PRPSLLTPTGDPR ddPTM_PC-9_AZD4547_30min_R2 1 LLSPRPSLLTPTGDPR 16 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 LLS(0.679)PRPS(0.079)LLT(0.241)PT(0.002)GDPR 61.409 0.019619 68264000.0 38752.0 31695.0 44022.0 75418.0 66698.0 48353.0 44908.0 53526.0 47725.0 51311.0 True False 51074.32990832677 41939.78892049364 43438.2395165362 58031.5452964847 57438.133991283954 45329.47926621376 48904.725001676474 45254.78660511696 50247.64606748147 49514.61750785286 1.0315000393616398 0.8470183358246102 0.8772811283384555 1.1720083526300304 1.1600237845354344 0.9154767126904424 0.9876825766435606 0.9139682155060512 1.014804286017404 1.0 15.59556687429596 LLS(ph)PRPSLLTPTGDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLSPRPSLLTPTGDPR 16 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 LLS(0.73)PRPS(0.218)LLT(0.048)PT(0.004)GDPR 66.26100000000001 0.012752 47874000.0 50158.0 47044.0 65671.0 60529.0 78876.0 61243.0 75022.0 70748.0 61542.0 54741.0 True False 58648.758734343 51714.21741703522 67236.84569865455 57137.75636766572 63420.81401610369 58031.309267860175 67915.37304775565 68890.93996370239 62441.93532397461 64665.10997048243 0.9069614009952862 0.7997236444914595 1.0397700665682936 0.8835948225209436 0.9807578467747643 0.8974129835138241 1.0502630101264323 1.0653494596258928 0.9656201830086947 1.0 15.980699896258514 -5.702047872209869 0.44917418853271995 1.0224584529473884 0.8276803400338899 0.32357723442873376 0.06677407837058125 2.6505900576440777 0.750191198726779 0.054633734944884216 0.2546479266834877 1.9858760025044313e-06 5.702047872209869 -0.19477811291349845 LLS(ph)PRPSLLTPTGDPR ddPTM_PC-9_Lapatinib_30min_R1 1 LLSPRPSLLTPTGDPR 16 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 LLS(0.462)PRPS(0.462)LLT(0.073)PT(0.003)GDPR 61.52 0.019409 56000000.0 76817.0 53065.0 67870.0 60340.0 62579.0 62439.0 54638.0 51333.0 62971.0 50644.0 True False 75721.57549348762 52942.13125280387 62289.99058577631 64777.60488833927 58898.226255047746 59768.62952241805 57466.888294212775 53718.118580329836 55878.54286597283 59397.747921111826 1.2748223315479237 0.8913154640663837 1.0486928000789824 1.0905734165943903 0.9915902254959648 1.0062440347367851 0.9674927132007851 0.9043797191044128 0.940751877330215 1.0 15.858120611507522 -4.749723491117567 24.99952548254002 0.9853779299573329 1.2748229758064211 0.6966938123103839 0.057864072110238175 330.0957975863557 704319.1853156112 0.015506695790608706 0.2462864674794849 1.7794119747808396e-05 4.749723491117567 0.28944504584908826 LLS(ph)PSNEK ddPTM_PC-9_AZD4547_30min_R2 2 LLSPSNEK 8 0 Q14694;Q14694-3;Q14694-2;H3BNA1;J3KT19 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 LLS(0.943)PS(0.057)NEK;LLS(0.939)PS(0.061)NEK 113.5 0.0037129 51273000.0 385950.0 312100.0 456030.0 652770.0 540440.0 408700.0 376320.0 491650.0 375530.0 476140.0 True False 508674.07174129586 412980.2215518556 449982.74423529155 502283.961695965 465409.2346734464 383143.92439148633 409811.75097156205 415676.7894930654 395379.7491403102 459470.48352573573 1.1070875931746422 0.8988177398967215 0.9793507099354016 1.0931800402970415 1.0129252070821608 0.8338814747172454 0.8919218223266082 0.9046865998951217 0.8605117484508976 1.0 18.80961265991457 -6.743115195862263 24.903083882508277 0.8918508438376168 1.013635177036012 0.4392235047108266 0.0675450259922931 220.2739511658914 299357.83132571605 0.022047122856120538 0.02200603646166855 1.8066948397587147e-07 6.743115195862263 0.1217843331983951 LLS(ph)PSNEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLSPSNEK 8 0 Q14694;Q14694-3;Q14694-2;H3BNA1;J3KT19 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 LLS(0.5)PS(0.5)NEK 79.20100000000001 0.021047 14257000.0 49884.0 53079.0 54243.0 66830.0 59758.0 56229.0 56046.0 59417.0 49655.0 42111.0 True False 58328.375946089676 58348.33233310966 55536.358837723084 63085.7317657833 48048.84887639232 53280.25225450271 50736.91714209863 57857.36670751538 50381.11043696924 49745.3909495074 1.1725382961668587 1.172939466740435 1.1164121495013204 1.2681723987216549 0.965895492210784 1.0710590717556783 1.019932021312239 1.1630698965908581 1.0127794650987287 1.0 15.60227524164142 -6.263951267137549 24.995727064634334 1.047613443161263 1.1771098950889924 0.5709333788077748 0.06067892692622816 179.07286727217158 1781947.7180469318 0.01805611109585447 0.021413388927532327 5.445637557641097e-07 6.263951267137549 0.12949645192772952 LLS(ph)PSNEK ddPTM_PC-9_Lapatinib_30min_R1 2 LLSPSNEK 8 0 Q14694;Q14694-3;Q14694-2;H3BNA1;J3KT19 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 LLS(0.859)PS(0.141)NEK;LLS(0.769)PS(0.231)NEK 111.65 0.0037426 49248000.0 379630.0 363160.0 390960.0 365970.0 348600.0 358040.0 363060.0 340810.0 385710.0 288380.0 True False 374216.4065843837 362319.1253324837 358816.777949243 392884.65464013076 328096.03337396967 342727.463832005 381857.47033377667 356645.2767880749 342267.27809363673 338226.0987578039 1.106409020352837 1.071233493403276 1.0608784457114993 1.1616036020965568 0.9700494272291856 1.0133087455129368 1.1290006056191904 1.0544581807788302 1.0119481593841362 1.0 18.367628462084518 -6.261333904567585 24.9999999880069 1.0366531466504227 1.0951775415104554 0.3418655636906027 0.046976798598412035 14.004118367537455 3319329.526237354 0.014893786820035206 0.018073403122288997 5.478555876489757e-07 6.261333904567585 0.05852439486003269 LLS(ph)PYSPQTQETDSAVQK ddPTM_PC-9_Lapatinib_30min_R1 1 LLSPYSPQTQETDSAVQK 18 0 Q9P265 Q9P265 DIP2B Disco-interacting protein 2 homolog B 1 LLS(0.999)PYS(0.001)PQTQETDSAVQK 179.9 9.7088e-09 4605100.0 65906.0 63253.0 63762.0 51803.0 50234.0 52900.0 53092.0 44381.0 54621.0 40450.0 True False 64966.168354319845 63106.54156475277 58519.734488437694 55612.76542974212 47279.33488384393 50637.59031592294 55840.8439788489 46443.10328080606 48469.00779537094 47441.72860376299 1.3693887273147727 1.3301906027038668 1.2335076358030517 1.1722331176889498 0.9965769856053225 1.0673639390093064 1.1770406690961026 0.9789504861575024 1.0216534941251376 1.0 15.533868956942696 -5.6758539160785615 1.2600385334246575 1.0445028579605826 1.371618093640588 0.8314991546820707 0.05584053800370254 0.20891183470556976 0.6381130215030312 0.020020164718653283 0.058229741838822104 2.1093375498793947e-06 5.6758539160785615 0.32711523568000533 LLS(ph)SNEDDANILSSPTDR ddPTM_PC-9_AZD4547_30min_R2 5 LLSSNEDDANILSSPTDR 18 0 H0YEG1;F5GY88;A0A0B4J1W0;O75448-2;O75448 H0YEG1 MED24 Mediator of RNA polymerase II transcription subunit 24 1 LLS(0.479)S(0.479)NEDDANILS(0.042)SPTDR;LLS(0.751)S(0.249)NEDDANILSSPTDR;LLS(0.745)S(0.251)NEDDANILS(0.005)SPTDR;LLS(0.952)S(0.048)NEDDANILSSPTDR;LLS(0.88)S(0.12)NEDDANILSSPTDR 247.28 1.522e-53 29182200.0 63021.9 51353.5 68803.6 109882.0 84962.5 72118.8 63377.1 93145.3 60700.200000000004 64229.7 True False 83061.55326304659 67952.51460257354 67891.21930852637 84550.40255997688 73166.92343450294 67609.20003524543 69017.53912228892 78751.83415105945 63908.68865008565 61981.03775299913 1.3401123355510036 1.0963436087238707 1.095354672489995 1.3641333805496934 1.180472707250897 1.0908045829222013 1.1135266788744482 1.2705794708519351 1.0311006554096176 1.0 15.919539289823238 -6.566705178790034 7.413031831069057 1.1202524496288602 1.2138037915870137 0.22068820541701606 0.10597883971875381 0.43390534046243634 60.22369713722771 0.03502215771379497 0.035146293101204894 2.712032072603868e-07 6.566705178790034 0.09355134195815351 LLS(ph)SNEDDANILSSPTDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LLSSNEDDANILSSPTDR 18 0 H0YEG1;F5GY88;A0A0B4J1W0;O75448-2;O75448 H0YEG1 MED24 Mediator of RNA polymerase II transcription subunit 24 1 LLS(0.63)S(0.369)NEDDANILS(0.001)SPTDR;LLS(0.5)S(0.5)NEDDANILSSPTDR;LLS(0.925)S(0.073)NEDDANILS(0.002)SPTDR 234.62 3.1095999999999996e-43 17101300.0 25462.199999999997 21158.100000000002 20180.1 19689.9 26108.3 31179.1 35201.9 34038.2 35450.1 26101.9 True False 29772.44755862653 23258.536338988448 20661.270117455435 18586.73873851709 20992.56603499973 29544.013108331383 31867.321192314175 33144.73331645404 35968.490647499784 30833.967847473272 0.9655730234234602 0.7543153853581772 0.6700814575555364 0.6028007433380068 0.6808259689068851 0.9581644910080038 1.0335134728670863 1.074942202716545 1.1665216369630245 1.0 14.91223293313781 -6.93273490973964 3.18790154136038 1.070815952533542 0.7250055718553525 0.7230208332817201 0.09799828697047716 0.1404843957173746 2.8945611788791967 0.04057120382484948 0.03443345339748233 1.1675220467545227e-07 6.93273490973964 -0.34581038067818937 LLS(ph)SNEDDANILSSPTDR ddPTM_PC-9_Lapatinib_30min_R1 2 LLSSNEDDANILSSPTDR 18 0 H0YEG1;F5GY88;A0A0B4J1W0;O75448-2;O75448 H0YEG1 MED24 Mediator of RNA polymerase II transcription subunit 24 1 LLS(0.966)S(0.034)NEDDANILSSPTDR;LLS(0.808)S(0.192)NEDDANILSSPTDR 159.95 6.8633e-06 8970500.0 19374.7 24103.9 28403.0 17098.7 29550.0 32617.0 26312.6 33598.0 36547.0 22531.4 True False 19098.41322511516 24048.08890048921 26067.81497875061 18356.195437591105 27811.927097535277 31222.04694394064 27674.93767945941 35159.08573552923 32430.692003028526 26425.922468796653 0.7227151009644522 0.9100189001494591 0.9864486285968299 0.6946283695210956 1.0524486753631854 1.18149317136638 1.0472647723892166 1.3304771395225492 1.2272302713868255 1.0 14.68966621323611 -6.480506898835724 4.833013926413988 1.1673695063384386 0.8459244905334203 0.6390278389187092 0.11632452878636955 0.13441615220002212 7.3095160659137575 0.037428086800424414 0.04123453590988437 3.307448580837592e-07 6.480506898835724 -0.3214450158050183 LLS(ph)TDAEAVSTR ddPTM_PC-9_AZD4547_30min_R2 1 LLSTDAEAVSTR 12 0 Q15545 Q15545 TAF7 Transcription initiation factor TFIID subunit 7 1 LLS(0.874)T(0.126)DAEAVSTR 203.29 1.052e-07 10467000.0 11172.0 9899.4 15399.0 20419.0 15596.0 13984.0 19337.0 21793.0 17342.0 15989.0 True False 14724.46360796415 13099.187456681966 15194.79919847214 15711.715020405232 13430.764606555891 13109.57826936765 21057.955539267346 18425.392603320164 18258.662715605315 15429.229976672841 0.9543226480016038 0.8489851714237443 0.9848060610571536 1.0183084343262414 0.8704753657092161 0.8496586212784288 1.364809233584856 1.1941874371681 1.1833813316160455 1.0 13.913378442977478 -7.249833532062974 24.999706736043375 1.2017767915108273 0.9228292638985367 0.636731173560864 0.09756358489015686 443.47232429222424 955268.1349745532 0.036811080704373986 0.028268016145170397 5.625569156422497e-08 7.249833532062974 -0.2789475276122906 LLS(ph)TDAEAVSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLSTDAEAVSTR 12 0 Q15545 Q15545 TAF7 Transcription initiation factor TFIID subunit 7 1 LLS(0.773)T(0.227)DAEAVSTR;LLS(0.992)T(0.008)DAEAVSTR 190.34 0.00016591 7519200.0 13979.3 12835.4 12507.35 19270.9 19074.3 18519.4 18229.3 27062.8 22715.2 16328.6 True False 16345.719386239509 14109.61368579657 12805.572658389014 18191.213950100766 15336.827841008244 17548.210062459537 16502.48873529704 26352.43017540682 23047.366827063608 19288.845922873516 0.8474182152523742 0.7314908181761566 0.6638848539509372 0.9430949898629688 0.7951138135652375 0.9097594606036092 0.8555456765678087 1.3662004601403868 1.1948546283804924 1.0 14.235479207168959 -7.684631892431872 7.056009956835351 1.2089434028028139 0.8163042953616768 0.6898352294068613 0.11231042689450114 0.11280538725399389 8.535055030761509 0.05335965714059434 0.030428527865824197 2.067131512082188e-08 7.684631892431872 -0.39263910744113706 LLS(ph)TDAEAVSTR ddPTM_PC-9_Lapatinib_30min_R1 1 LLSTDAEAVSTR 12 0 Q15545 Q15545 TAF7 Transcription initiation factor TFIID subunit 7 1 LLS(0.908)T(0.092)DAEAVSTR 148.13 0.00014484 7921500.0 14375.0 20331.0 13940.0 11023.0 21320.0 19884.0 28137.0 23610.0 14155.0 25831.0 True False 14170.00986394786 20283.92481863291 12793.90700995611 11833.668191650047 20065.99951673273 19033.60767186791 29593.796184601662 24707.006792542554 12560.714841241926 30295.853932356036 0.46772109132775624 0.6695280768095345 0.4222989402616637 0.3906035531486262 0.6623348383424241 0.628257837338593 0.9768266063956502 0.8155243568214929 0.41460177584983193 1.0 14.886832750128756 -6.711836447887383 2.162380106145172 0.7814229029256309 0.5006120789214099 0.37651264356095215 0.17031090626807974 0.355549783503249 3.4142464229210456 0.06594580512927292 0.06275549438724862 1.9416169386087313e-07 6.711836447887383 -0.28081082400422097 LLS(ph)VT(ph)S(ph)RPGISTFGY(ph)NRNNK ddPTM_PC-9_Lapatinib_30min_R1 1 LLSVTSRPGISTFGYNRNNK 20 2 F8W1T6;Q15434;F8VZR4;F8VQS9 F8W1T6 RBMS2 RNA-binding motif, single-stranded-interacting protein 2 4 LLS(0.997)VT(0.992)S(0.985)RPGIS(0.023)T(0.023)FGY(0.981)NRNNK 47.54600000000001 0.046027 0.0 2291.8 2178.1 11212.0 2029.1 5555.2 5339.8 3849.6 4486.5 11074.0 3980.7 True False 2259.118511735352 2173.0567432720645 10290.192639571596 2178.326782879172 5228.454057943418 5111.429201681764 4048.9134517625366 4694.959168773493 9826.729505610248 4668.75869105066 0.4838799049661226 0.4654463610290038 2.2040532228183944 0.4665751492050149 1.1198809799199119 1.0948154616514323 0.8672355372582701 1.0056118723319445 2.104784195517896 1.0 12.188823308191596 -8.059945657129557 21.14492746549668 1.5533377533962607 0.976045510833719 0.1592730870365754 0.5410556225890654 90.8884403124778 32056.685422937742 0.35298847731877386 0.13341728038897846 8.710725796505084e-09 8.059945657129557 -0.5772922425625416 LLSDS(ph)LPPSTGTFQEAQSR ddPTM_PC-9_Lapatinib_30min_R1 1 LLSDSLPPSTGTFQEAQSR 19 0 Q9Y490 Q9Y490 TLN1 Talin-1 1 LLS(0.068)DS(0.932)LPPSTGTFQEAQSR 197.1 7.282300000000001e-15 4776800.0 16067.0 16234.0 20069.0 18371.0 24721.0 22379.0 21695.0 19867.0 23863.0 20578.0 True False 15837.881633673058 16196.411170413994 18419.004288580298 19722.064623859475 23266.95938335599 21421.90233799698 22818.260945549722 20790.093348049268 21175.29765146989 24134.87988153854 0.6562237604417458 0.6710790047396544 0.7631695031832133 0.8171602560551977 0.9640387479679793 0.8875910070048952 0.9454474626577305 0.8614127540759879 0.8773732355580306 1.0 14.55883202610657 -5.694216968309612 1.5175244304658433 0.9154708256421099 0.6563394209885235 0.8538119505808613 0.04270789297920353 0.14645041672284842 0.6727532224782966 0.013504729694988272 0.03348844107864983 2.022008755000997e-06 5.694216968309612 -0.2591314046535864 LLSFS(ph)PEEFPTLK ddPTM_PC-9_AZD4547_30min_R2 1 LLSFSPEEFPTLK 13 0 Q5JSZ5;Q5JSZ5-5;A0A1W2PQP5 Q5JSZ5 PRRC2B Protein PRRC2B 1 LLSFS(0.999)PEEFPT(0.001)LK 141.73 7.8434e-05 9461900.0 53248.0 50528.0 65528.0 98258.0 78680.0 66806.0 54734.0 68674.0 62033.0 73543.0 True False 70179.75637279582 66860.18787110597 64659.05590476537 75606.13617096706 67756.64011565907 62628.6102591086 59605.21996619216 58062.011271527976 65311.93773712055 70968.28195474688 0.9888890422561748 0.9421136602086485 0.9110979457836587 1.0653510848575638 0.9547453911715699 0.8824873384851546 0.8398853448953378 0.8181402969364733 0.9202975743271745 1.0 16.114886760634782 -6.725142253907875 4.5769449655800605 0.8769511088410857 0.9739076868131953 0.3006177259619277 0.059568386780909914 0.21963816631009928 10.372864543684955 0.020303973042048236 0.01958978975594304 1.88303219801362e-07 6.725142253907875 0.09695657797210955 LLSGAS(ph)TK ddPTM_PC-9_Lapatinib_30min_R1 1 LLSGASTK 8 0 Q7Z6J0 Q7Z6J0 SH3RF1 E3 ubiquitin-protein ligase SH3RF1 1 LLS(0.01)GAS(0.942)T(0.048)K 94.40899999999999 0.019479 0.0 55341.0 42414.0 40551.0 57060.0 49161.0 28410.0 34498.0 31610.0 45266.0 44779.0 True False 54551.827191703516 42315.79298890839 37217.05331138669 61256.38274658001 46269.44663424476 27194.970526944628 36284.137639989625 33078.71599797843 40167.66640788818 52518.99048573306 1.0387066980375923 0.8057236553395595 0.7086399218106985 1.1663663406329277 0.8810041131086477 0.5178121337715397 0.6908765249371334 0.6298429518930749 0.7648217537387708 1.0 15.680551564721146 -6.573559369499881 13.370642309462559 0.6960101605690476 0.9199938120876027 0.2691550608899166 0.16304119976319736 1.604831191754524 421.4886569197867 0.052878166595663335 0.05287870767724707 2.669565803661552e-07 6.573559369499881 0.22398365151855504 LLSGDS(ph)TEKR ddPTM_PC-9_AZD4547_30min_R2 1 LLSGDSTEKR 10 1 Q6P0Q8;Q6P0Q8-2;A0A669KBJ4;E7ERL6 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 LLS(0.108)GDS(0.737)T(0.155)EKR 75.566 0.035744 6563700.0 36714.0 33021.0 36035.0 46194.0 44764.0 36399.0 32593.0 45422.0 39939.0 39368.0 True False 48388.28830136012 43694.39248915037 35557.152355149265 35544.68699018556 38549.29128288457 34122.96477593772 35493.71385899263 38403.07359372315 42050.09400291551 37989.73830268662 1.2737199692143737 1.1501630293162697 0.9359672886358018 0.9356391641074255 1.0147290559292528 0.8982153155165208 0.9342974035828651 1.0108801826362488 1.1068803282580586 1.0 15.213322153391905 -5.050091883639756 3.167249946055977 0.9754424138751508 1.2643463871984222 0.740454024043802 0.0570418796234629 0.12806438604493445 2.4476704582817916 0.015749595169501782 0.06556063825355765 8.910623962082107e-06 5.050091883639756 0.28890397332327133 LLSGPSQES(ph)PQTLGK ddPTM_PC-9_AZD4547_30min_R2 2 LLSGPSQESPQTLGK 15 0 E7EVL6;C9JZE3;C9JYJ8;Q9BWE0;Q9BWE0-4 E7EVL6 REPIN1 Replication initiator 1 1 LLSGPS(0.001)QES(0.586)PQT(0.413)LGK;LLSGPS(0.087)QES(0.913)PQTLGK 166.77 0.00017536 13895200.0 71743.0 65378.0 80289.0 110814.0 91063.0 83059.0 66457.0 91074.0 72402.0 93762.0 True False 94555.78165289754 86510.15996352851 79224.3154000993 85267.54435923322 78420.47431179785 77865.30759978606 72371.54425573212 77000.60597232057 76229.02190838744 90479.42091893165 1.045052904766248 0.9561307873647916 0.875605906796013 0.9423971052559211 0.8667216646099177 0.860585830556457 0.7998674562757874 0.851028943270007 0.842501213360855 1.0 16.46530207545478 -3.2382295875597698 0.6506147364148375 0.8614864376642676 2.305587264256952 0.48481313309838137 0.053141866178601456 15.956264859231261 1.0368805559700471 0.02170782838352261 26.66681733822914 0.000577790520647484 3.2382295875597698 1.4441008265926842 LLSGPSQES(ph)PQTLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLSGPSQESPQTLGK 15 0 E7EVL6;C9JZE3;C9JYJ8;Q9BWE0;Q9BWE0-4 E7EVL6 REPIN1 Replication initiator 1 1 LLSGPS(0.002)QES(0.756)PQT(0.242)LGK 117.53 0.0018685 0.0 19321.0 16757.0 16293.0 20383.0 22019.0 15432.0 18845.0 16773.0 16735.0 15605.0 True False 22591.663692855414 18420.52421684505 16681.486911546595 19241.006592577603 17704.535014714063 14622.71875351662 17059.865174015056 16332.72652246252 16979.717715490482 18434.06297088797 1.2255390321999735 0.9992655577848301 0.9049273043002438 1.043774593965747 0.9604250046597965 0.7932444831402374 0.9254533415100556 0.8860079597349759 0.9211055502146073 1.0 14.17008646364537 -1.57756032640566 0.9550650895544004 0.9172337109941254 199.99136830241306 0.6556777697488223 0.0641014255375484 668.8731150031215 1.2842648741582283 0.02134599605153564 290744.3694077629 0.02645085249187726 1.57756032640566 199.07413459141893 LLSGPSQES(ph)PQTLGK ddPTM_PC-9_Lapatinib_30min_R1 2 LLSGPSQESPQTLGK 15 0 E7EVL6;C9JZE3;C9JYJ8;Q9BWE0;Q9BWE0-4 E7EVL6 REPIN1 Replication initiator 1 1 LLSGPSQES(0.996)PQT(0.004)LGK;LLSGPS(0.019)QES(0.904)PQT(0.077)LGK 196.45 1.0422999999999998e-09 10900700.0 52904.0 49698.0 50200.0 42698.0 40640.0 35383.0 33490.0 33223.0 45226.0 26000.0 True False 52149.57925859462 49582.92733443604 46072.74977760383 45838.15335635254 38249.6351013142 33869.75157180157 35223.948332171494 34766.66186652441 40132.171629106866 30494.065357177693 1.7101550300940656 1.6259861305362229 1.5108759438255492 1.5031827609552608 1.2543304624455722 1.1106997763362931 1.1551083110629092 1.1401123943069478 1.3160649837611946 1.0 14.896240877541173 -6.102594927361748 1.256279648210945 1.1459154472727682 1.6570617139448025 0.8719238416032855 0.08194692716374938 0.1537793527928578 0.493842562552791 0.03130169671212746 0.05293540008239919 7.895962419100309e-07 6.102594927361748 0.5111462666720343 LLSGS(ph)ESSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLSGSESSSK 10 0 G3XAI9;Q5BKY9-2;Q5BKY9 G3XAI9 FAM133B Protein FAM133B 1 LLS(0.093)GS(0.532)ES(0.358)S(0.015)S(0.003)K 107.11 0.0022188000000000004 8274700.0 42976.0 50706.0 46343.0 55768.0 64345.0 59733.0 58848.0 54346.0 56836.0 40122.0 True False 50250.987985308966 55739.7565757203 47447.99287680622 52643.499762295425 51737.05915444735 56600.49632606324 53273.49141737535 52919.475084346734 57667.1189768519 47395.800994422774 1.0602413490431815 1.1760484137039773 1.001101192115934 1.1107207528466534 1.0915958390604144 1.1942090889596657 1.124012893539751 1.1165435328453241 1.2167136701337276 1.0 15.532471629540863 -6.572807362833742 24.998909097525914 1.137822243677451 1.0889873643517547 0.08431466570605783 0.0675603916414429 243.57839189442348 121956.34067850404 0.02099174976039188 0.02099175397810743 2.6741923196482247e-07 6.572807362833742 -0.0488348793256963 LLSMPGAQGAAAAGSEPPPAT(ph)TSPEGQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLSMPGAQGAAAAGSEPPPATTSPEGQPK 29 0 A0A0G2JIS2;A2ABF8;A0A0G2JIR1;A2ABF9;A0A0G2JK64;Q96KQ7-2;Q96KQ7;Q96KQ7-3 A0A0G2JIS2 EHMT2 Histone-lysine N-methyltransferase EHMT2 1 LLSMPGAQGAAAAGSEPPPAT(0.333)T(0.333)S(0.333)PEGQPK 111.9 6.5577e-12 7466700.0 20487.0 22212.0 22127.0 31326.0 31111.0 24221.0 24565.0 23151.0 25210.0 17267.0 True False 23955.04446330567 24417.060566005985 22654.59159711481 29570.905780262292 25015.02288218216 22950.80812136639 22238.025364801284 22543.310780512114 25578.648557365686 20397.370414503202 1.1744182694389294 1.1970690373228037 1.1106623617035776 1.4497410783517666 1.22638469439157 1.1251846515003527 1.0902398158631916 1.1052067164737607 1.2540169657937097 1.0 14.316095554565704 -6.756898695026647 6.116659523139358 1.119480515541894 1.2356207284806506 0.25324187207183 0.1000798980752727 0.2398327738944265 34.328893380839475 0.03503143914281633 0.03307864488829967 1.7502549112851758e-07 6.756898695026647 0.11614021293875654 LLSMPGAQGAAAAGSEPPPATTS(ph)PEGQPK ddPTM_PC-9_AZD4547_30min_R2 1 LLSMPGAQGAAAAGSEPPPATTSPEGQPK 29 0 A0A0G2JIS2;A2ABF8;A0A0G2JIR1;A2ABF9;A0A0G2JK64;Q96KQ7-2;Q96KQ7;Q96KQ7-3 A0A0G2JIS2 EHMT2 Histone-lysine N-methyltransferase EHMT2 1 LLSMPGAQGAAAAGSEPPPAT(0.181)T(0.181)S(0.637)PEGQPK 121.9 7.6209e-14 7938000.0 21634.0 16099.0 21063.0 23045.0 25418.0 20319.0 19433.0 30277.0 16183.0 20810.0 True False 28513.16198484571 21302.686916896262 20783.69085768029 17732.331291700793 21889.149446616928 19048.449717911975 21162.49935329069 25598.385346245333 17038.400341750712 20081.448234071024 1.4198757804962039 1.0608142733825956 1.034969720083127 0.8830205413977753 1.0900184683631973 0.9485595608385246 1.0538333245002474 1.2747280498830778 0.8484647194340621 1.0 14.293575696884462 -4.756629788149121 4.065483718577047 1.0243562010147385 1.4644630993273156 0.5348420205272737 0.1119128892305589 0.1972177596387808 6.165649891999394 0.02739976147519784 0.2647266238239017 1.7513389713947433e-05 4.756629788149121 0.4401068983125771 LLSMPGAQGAAAAGSEPPPATTS(ph)PEGQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLSMPGAQGAAAAGSEPPPATTSPEGQPK 29 0 A0A0G2JIS2;A2ABF8;A0A0G2JIR1;A2ABF9;A0A0G2JK64;Q96KQ7-2;Q96KQ7;Q96KQ7-3 A0A0G2JIS2 EHMT2 Histone-lysine N-methyltransferase EHMT2 1 LLSMPGAQGAAAAGSEPPPAT(0.199)T(0.199)S(0.602)PEGQPK 89.805 1.8337e-08 7862000.0 14082.0 12579.0 12820.0 16762.0 16604.0 13050.0 15671.0 16664.0 15952.0 15085.0 True False 16465.804467822058 13827.759988285128 13125.677420120743 15822.879483137218 13350.565392811308 12365.63502678796 14186.529431785091 16226.587656967462 16185.267821780946 17819.7910872057 0.9240178174504088 0.775977671153127 0.7365786364097585 0.8879385513390092 0.749198760382594 0.6939270480935251 0.7961108725887798 0.9105935966116836 0.9082748356910697 1.0 14.121192802872862 -7.840036815880759 3.2376188323460675 0.9435331992789608 0.7890976945032896 0.49355133284108355 0.06784066042847951 0.22171791822573753 4.572867561897218 0.04337068949739652 0.019010202628660846 1.4453172435553775e-08 7.840036815880759 -0.15443550477567125 LLSMPGAQGAAAAGSEPPPATTS(ph)PEGQPK ddPTM_PC-9_Lapatinib_30min_R1 1 LLSMPGAQGAAAAGSEPPPATTSPEGQPK 29 0 A0A0G2JIS2;A2ABF8;A0A0G2JIR1;A2ABF9;A0A0G2JK64;Q96KQ7-2;Q96KQ7;Q96KQ7-3 A0A0G2JIS2 EHMT2 Histone-lysine N-methyltransferase EHMT2 1 LLSMPGAQGAAAAGSEPPPAT(0.212)T(0.212)S(0.575)PEGQPK 105.61 1.9489000000000003e-11 4814700.0 35592.0 26023.0 32154.0 21040.0 30215.0 31241.0 27631.0 24216.0 26732.0 20377.0 True False 35084.45155322658 25962.745342348368 29510.42223802935 22587.35178738246 28437.81310497557 29904.895256327956 29061.597980478677 25341.163764854333 23721.160659560523 23899.13729935423 1.4680216743294152 1.0863465495488782 1.2347902716482884 0.945111595638759 1.1899096084001315 1.2512960146530479 1.2160103361247243 1.0603380133532714 0.9925530098612171 1.0 14.544670920918364 -4.758115125005791 24.996548670886657 1.1195788001227003 1.4680221583323028 0.5108092117721321 0.10505041260619438 82.23683617650701 618275.1932375225 0.02653509439343542 0.18700725649426153 1.7453594227759674e-05 4.758115125005791 0.3484433582096025 LLSPQMS(ph)GEEEDSDLAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLSPQMSGEEEDSDLAAK 18 0 P42858;A0A3B3IU44 P42858 HTT Huntingtin 1 LLS(0.234)PQMS(0.741)GEEEDS(0.025)DLAAK 76.158 0.0048528 2617600.0 7594.9 7201.2 9005.3 11912.0 11162.0 8245.1 10955.0 9642.1 9639.1 10528.0 True False 8880.566563887347 7916.087544927175 9220.020504790435 11244.609259225068 8974.886227087436 7812.7124413309975 9917.263092668354 9389.00509164942 9780.053602114387 12436.643060397855 0.7140646009344626 0.636513205893515 0.7413592606955048 0.9041514824069693 0.721648613978982 0.6282010670716367 0.7974228290146887 0.7549468973301112 0.7863901500282761 1.0 13.602309500574039 -14.522878742876946 0.22703874508423763 2.3749114234315796 0.7123790712439876 0.5407704002056894 0.07309142919748574 133.87410085270156 1.3367120284579155 84.30683930433081 0.13970189364326813 3.00000001660204e-15 14.522878742876946 -1.662532352187592 LLSPQMS(ph)GEEEDSDLAAK ddPTM_PC-9_Lapatinib_30min_R1 1 LLSPQMSGEEEDSDLAAK 18 0 P42858;A0A3B3IU44 P42858 HTT Huntingtin 1 LLS(0.08)PQMS(0.911)GEEEDS(0.009)DLAAK 90.861 0.0011417 3253100.0 9487.7 8605.8 8927.3 8934.0 11507.0 11989.0 9269.0 10766.0 13387.0 10690.0 True False 9352.403658168907 8585.873798838773 8193.33185437455 9591.036162950335 10830.180883632436 11476.258417724019 9748.90346643468 11266.227663215297 11879.21508864046 12537.752256470367 0.7459394209470366 0.6848016792170906 0.6534928818797014 0.7649725378805984 0.8638056217806742 0.915336192881101 0.777563893990931 0.8985843261818423 0.9474756595632957 1.0 13.613991107345846 -6.626193109271444 0.3448958204526077 0.9969529141873005 0.6247930176561101 0.7518476833021163 0.05499536024436122 1.1004847508590014 0.2555386408604616 0.07040230819694743 0.15389100877630624 2.3648679238921064e-07 6.626193109271444 -0.3721598965311904 LLSPQMSGEEEDS(ph)DLAAK ddPTM_PC-9_Lapatinib_30min_R1 1 LLSPQMSGEEEDSDLAAK 18 0 P42858;A0A3B3IU44 P42858 HTT Huntingtin 1 LLS(0.025)PQMS(0.09)GEEEDS(0.885)DLAAK 83.182 0.020987000000000002 0.0 5651.8 4213.4 6727.9 6625.0 5425.6 4755.2 5178.2 5401.8 6493.1 6337.1 True False 5571.204295586816 4203.644131170523 6174.7580324450355 7112.22460035213 5106.476875140013 4551.831180912606 5446.301858872811 5652.787348240426 5761.778702625785 7432.459291345026 0.7495775055336515 0.5655791665170095 0.8307826239472899 0.9569140336408161 0.687050769465555 0.6124259820989719 0.7327725111410887 0.760554094769547 0.7752183330940379 1.0 12.859623940967158 -8.97867411339282 1.4452809630918404 0.9999192560569969 0.7347939765483575 0.3703209407334739 0.10250403247423077 2.536419650802478 6.77359457528035 0.10589622934994737 0.030828527367729168 1.050330281583286e-09 8.97867411339282 -0.2651252795086394 LLSPRPS(ph)LLTPTGDPR ddPTM_PC-9_AZD4547_30min_R2 1 LLSPRPSLLTPTGDPR 16 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 LLS(0.179)PRPS(0.803)LLT(0.019)PTGDPR 90.42200000000001 0.0016587 74168000.0 128220.0 104060.0 150400.0 245090.0 203430.0 152920.0 135380.0 191240.0 130460.0 183710.0 True False 168991.29285832072 137695.35999579012 148405.5977303858 188588.28710275335 175187.2559574033 143357.88822595144 147428.55773418926 161688.25225801638 137355.8492606312 177278.36881697242 0.9532538796811272 0.7767183380277545 0.8371331410636131 1.0637975087499685 0.9882043541266557 0.8086597884593494 0.831621808785927 0.9120585514014304 0.7748032102125305 1.0 17.435656986396324 -9.936671425279778 15.217605102988673 0.9999995816727993 0.8840278009452873 0.12955444855913367 0.09100496773444519 0.0 0.0 0.09249801152384404 0.02243406303955345 1.1569872544422754e-10 9.936671425279778 -0.11597178072751202 LLSPRPS(ph)LLTPTGDPR ddPTM_PC-9_Lapatinib_30min_R1 1 LLSPRPSLLTPTGDPR 16 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 LLS(0.397)PRPS(0.485)LLT(0.116)PT(0.001)GDPR 59.733000000000004 0.022798 52863000.0 91984.0 73563.0 82670.0 80660.0 92666.0 75629.0 73710.0 71429.0 96508.0 81144.0 True False 90672.29129220046 73392.6693931974 75873.19171542836 86592.00547387234 87215.5680683657 72394.5239698098 77526.34313420003 74747.85210438474 85638.25276570664 95169.6322824164 0.9527439490690681 0.7711773980107883 0.7972416189470424 0.909870127657004 0.9164222449610084 0.7606893316029494 0.8146121958750475 0.7854170528112381 0.8998485200780714 1.0 16.538213676352527 -8.556345159266122 5.9404728644967415 0.9999837928049983 0.8366798143448563 0.3834766053025479 0.06319036273869078 0.25144927363932107 37.924285159810445 0.06165340414263258 0.015982348971443617 2.7775049444455354e-09 8.556345159266122 -0.163303978460142 LLSPRPSLLT(ph)PTGDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLSPRPSLLTPTGDPR 16 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 LLS(0.036)PRPS(0.045)LLT(0.46)PT(0.46)GDPR 61.015 0.031114 16101000.0 40401.0 34723.0 45212.0 48825.0 51547.0 57454.0 55757.0 51674.0 51972.0 36126.0 True False 47240.091343877226 38170.069963687456 46290.025547464844 46089.493542785734 41446.73538323564 54441.01109801345 50475.293314277435 50317.61225312872 52731.99217863585 42675.35782674134 1.1069641533099348 0.8944288204601587 1.0847015210838717 1.0800025094084864 0.9712100259711046 1.2757013384407871 1.1827737571458272 1.179078859922261 1.2356543650488807 1.0 15.381115629643727 -6.753859509374167 24.999188638250654 1.1863423527005104 1.0261696562940361 0.4053362986247391 0.08856276476588769 156.91510215871418 517521.47148035775 0.027979830046688362 0.027467120979831332 1.762546123101147e-07 6.753859509374167 -0.16017269640647425 LLSPRPSLLT(ph)PTGDPR ddPTM_PC-9_Lapatinib_30min_R1 1 LLSPRPSLLTPTGDPR 16 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 LLS(0.338)PRPS(0.222)LLT(0.436)PT(0.004)GDPR 63.691 0.02336 7405900.0 22860.0 22113.0 23835.0 20912.0 25864.0 24440.0 20827.0 18130.0 21302.0 18211.0 True False 22534.012207989435 22061.798707118665 21875.378305760692 22449.938240386982 24342.730370580455 23394.758172422637 21905.320152706347 18972.385986818997 18902.74443999544 21358.747085367802 1.055025003008101 1.0329163325423945 1.0241882737001375 1.0510887249452343 1.1397077868512655 1.0953244625687637 1.0255901277895174 0.8882724211766324 0.8850118578792999 1.0 14.382539399854782 -7.636662867736158 4.532698031489762 0.9158128514925675 1.065211025170489 0.6830129996090053 0.04302036725775649 0.12310959848393103 4.2986775981786405 0.02271093912393178 0.012564274356380713 2.3085385557740148e-08 7.636662867736158 0.1493981736779214 LLSPS(ph)NEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLSPSNEK 8 0 Q14694;Q14694-3;Q14694-2;H3BNA1;J3KT19 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 LLS(0.228)PS(0.772)NEK 88.134 0.011204 4181200.0 28484.0 36061.0 28914.0 35611.0 44933.0 35136.0 40464.0 38204.0 30514.0 22606.0 True False 33305.778615356 39640.89776115352 29603.419416955625 33615.831122419724 36128.70120423939 33293.40630660705 36630.956986009325 37201.185480484 30960.209523183523 26704.28885100247 1.2472070984996746 1.4844393716054871 1.10856423034251 1.2588176869258885 1.3529175558960123 1.2467437905711998 1.3717256127056239 1.3930790551304075 1.159372177852296 1.0 14.704783844577362 -8.528516260347873 4.627993030157724 1.0002981849483354 1.306387029100918 0.5040550286312623 0.09710934492447985 0.12923156085555862 10.072739367082155 0.09219828633066916 0.024035534623866556 2.9613090894348585e-09 8.528516260347873 0.30608884415258264 LLSPYS(ph)PQTQETDSAVQK ddPTM_PC-9_AZD4547_30min_R2 1 LLSPYSPQTQETDSAVQK 18 0 Q9P265 Q9P265 DIP2B Disco-interacting protein 2 homolog B 1 LLS(0.018)PY(0.017)S(0.951)PQT(0.013)QET(0.001)DSAVQK 82.449 0.0026668000000000004 5294400.0 9931.7 7347.0 12408.0 15270.0 12517.0 13254.0 8936.5 13398.0 10598.0 10651.0 True False 13089.77400780679 9721.774071584381 12243.461812756817 11749.737419148229 10779.230609147227 12425.22528476822 9731.831187705562 11327.646955411523 11158.188643754187 10278.111731912082 1.2735582516742736 0.9458716080503045 1.1912170379256144 1.143180549659424 1.048755928161322 1.2089015578795133 0.9468501064733129 1.1021136227037485 1.0856263226940404 1.0 13.327287620225986 -7.256396068087298 24.97393981210949 1.042156983019141 1.125612719263607 0.21378387996915094 0.0938063446523008 776.3072878041461 3844198.259751978 0.03473990311503422 0.02607301254462287 5.5412013571085344e-08 7.256396068087298 0.0834557362444659 LLSS(ph)NEDDANILSSPTDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLSSNEDDANILSSPTDR 18 0 H0YEG1;F5GY88;A0A0B4J1W0;O75448-2;O75448 H0YEG1 MED24 Mediator of RNA polymerase II transcription subunit 24 1 LLS(0.355)S(0.597)NEDDANILS(0.033)S(0.012)PT(0.003)DR;LLS(0.329)S(0.671)NEDDANILSSPTDR 144.4 0.00018487 3232700.0 11357.66 13921.8 11489.1 14865.2 19300.53 19731.8 24263.7 20493.3 19437.6 12555.68 True False 13280.287513989757 15303.8642980291 11763.043716654389 14032.351037628654 15518.729696513887 18697.02967215133 21965.266682024372 19955.372589446182 19721.838127673596 14831.925393291809 0.8953852693997619 1.0318191261230818 0.7930894610604355 0.9460909939565374 1.0463058089230077 1.2605935626272522 1.480945062733314 1.3454337222105774 1.3296883314012218 1.0 13.856418271681179 -6.663251788983555 2.4964252071070634 1.3241715970834356 0.9188559150080915 0.649986235060767 0.1268208976101156 0.16056220303197527 2.039488855855098 0.045051202591164866 0.04424891840244885 2.171441886630229e-07 6.663251788983555 -0.4053156820753441 LLSS(ph)NEDDANILSSPTDR ddPTM_PC-9_Lapatinib_30min_R1 1 LLSSNEDDANILSSPTDR 18 0 H0YEG1;F5GY88;A0A0B4J1W0;O75448-2;O75448 H0YEG1 MED24 Mediator of RNA polymerase II transcription subunit 24 1 LLS(0.322)S(0.678)NEDDANILSSPTDR 152.66 3.3293e-05 5348600.0 7623.2 7219.5 6935.3 3676.8 8608.5 9056.1 9558.2 9320.8 8285.2 7212.7 True False 7514.491770076335 7202.78369131476 6365.106405032184 3947.2041374452424 8102.164954962177 8668.79171380019 10053.076827368215 9753.878395253312 7352.033528976169 8459.405584681364 0.888300211504681 0.8514526959622144 0.7524295107162585 0.4666053776394171 0.9577700080528007 1.0247518725781384 1.1883904521108122 1.1530217221072876 0.8690957603793734 1.0 13.046340578011955 -6.503285766522017 16.94782966580392 1.0572099257439285 0.7440368231786435 0.546350413026413 0.13247279417338478 9.600884399443178 8304.492513047811 0.043756126747669426 0.04844011376292335 3.138442913429121e-07 6.503285766522017 -0.31317310256528497 LLSSNEDDANILS(ph)SPTDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLSSNEDDANILSSPTDR 18 0 H0YEG1;F5GY88;A0A0B4J1W0;O75448-2;O75448 H0YEG1 MED24 Mediator of RNA polymerase II transcription subunit 24 1 LLSSNEDDANILS(0.744)S(0.249)PT(0.007)DR;LLSSNEDDANILS(0.655)S(0.344)PT(0.001)DR 106.19 0.00032474 9431100.0 11928.2 9117.1 14164.2 13649.3 13670.3 12383.199999999999 14640.3 13216.3 13082.1 11125.8 True False 13947.408667311112 10022.185435185187 14501.928246027639 12884.573972627652 10991.702848069646 11733.803192622276 13253.464797406883 12869.38612882735 13273.400963598326 13142.819468215655 1.061218918896456 0.7625597733745525 1.1034107469176477 0.9803508298799554 0.8363276140748772 0.8927919325833458 1.0084186904840937 0.9791952297564787 1.0099355770425416 1.0 13.681987183099817 -7.282683928649984 23.95326207537572 0.9976536542695497 0.9360285610351757 0.08832513487613514 0.09389778707382314 1286.2515008562016 1450242.0353530617 0.038855876659803716 0.026232078710610608 5.215741648692542e-08 7.282683928649984 -0.06162509323437393 LLSSNEDDANILSS(ph)PTDR ddPTM_PC-9_AZD4547_30min_R2 1 LLSSNEDDANILSSPTDR 18 0 H0YEG1;F5GY88;A0A0B4J1W0;O75448-2;O75448 H0YEG1 MED24 Mediator of RNA polymerase II transcription subunit 24 1 LLSSNEDDANILS(0.007)S(0.987)PT(0.007)DR 154.31 1.8116e-05 7569100.0 9366.5 7836.8 9780.1 15048.0 12424.0 10284.0 8077.3 11323.0 10153.0 10667.0 True False 12344.85216469711 10369.892343023334 9650.40948379618 11578.916089282427 10699.142053850379 9640.93985427466 8796.164052196516 9573.29052665508 10689.666852239694 10293.55157678211 1.1992801583218238 1.0074163679728787 0.9375199037777606 1.124870847822782 1.0394023844970193 0.936599946321786 0.8545314983447437 0.9300279359602537 1.0384818857226161 1.0 13.329453219718298 -6.720728352664119 5.381497556913681 0.9412436506022456 1.056519630309039 0.32205437760423594 0.0789366883476552 0.23684788626667871 16.32138843531499 0.02742055024932121 0.026756898673413937 1.9022677594451408e-07 6.720728352664119 0.11527597970679337 LLSSNEDDANILSS(ph)PTDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LLSSNEDDANILSSPTDR 18 0 H0YEG1;F5GY88;A0A0B4J1W0;O75448-2;O75448 H0YEG1 MED24 Mediator of RNA polymerase II transcription subunit 24 1 LLSSNEDDANILS(0.243)S(0.753)PT(0.004)DR;LLSSNEDDANILS(0.209)S(0.786)PT(0.005)DR;LLSSNEDDANILS(0.289)S(0.557)PT(0.153)DR;LLSSNEDDANILS(0.01)S(0.989)PT(0.001)DR;LLSSNEDDANILS(0.023)S(0.976)PT(0.001)DR 228.08 4.3668999999999997e-35 18767400.0 39030.7 48761.9 54145.7 52543.1 57381.2 51025.9 47443.2 51366.9 47634.8 38766.0 True False 45637.82661853585 53602.659175829605 55436.73883671078 49599.28045402856 46137.76577439076 48350.01197803677 42949.03663697702 50018.57330272935 48331.36883381216 45793.968928512826 0.9965903302633428 1.1705178745154547 1.210568555943489 1.0830963468454995 1.007507469955588 1.055816150233977 0.9378753936795275 1.0922524182346236 1.0554090410739538 1.0 15.482869987263332 -6.001584526894799 24.95988296812001 1.02832404850244 1.1331010969508013 0.33586840421395237 0.06405404095745568 67.46688292803258 1062802.792842459 0.01821745440828822 0.026594802920907122 9.963581397107189e-07 6.001584526894799 0.10477704844836122 LLSSNEDDANILSS(ph)PTDR ddPTM_PC-9_Lapatinib_30min_R1 1 LLSSNEDDANILSSPTDR 18 0 H0YEG1;F5GY88;A0A0B4J1W0;O75448-2;O75448 H0YEG1 MED24 Mediator of RNA polymerase II transcription subunit 24 1 LLSSNEDDANILS(0.22)S(0.775)PT(0.005)DR 157.83 1.109e-05 6277500.0 37393.0 38738.0 42817.0 37339.0 35352.0 33511.0 28184.0 29235.0 39124.0 25602.0 True False 36859.768962963644 38648.30454105563 39296.751538399665 40085.034619252576 33272.66486470619 32077.812647956405 29643.229614628875 30593.36482761465 34717.44312601548 30027.271587479343 1.2275430638304576 1.2871067698728595 1.308702038542372 1.3349542765639446 1.1080815240829305 1.0682892901042693 0.9872102274849839 1.0188526366268773 1.1561970598917761 1.0 14.87398577066026 -6.406418465968068 3.6332432570322752 1.046312139675249 1.29040950860835 0.8366108031046766 0.05094976795010086 0.09601270910670195 2.29214642822608 0.017030891693921173 0.019320438956727477 3.9226678321202816e-07 6.406418465968068 0.24409736893310097 LLSSS(ph)LTADCSLR ddPTM_PC-9_AZD4547_30min_R2 2 LLSSSLTADCSLR 13 0 Q147X3;Q147X3-2 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 LLSS(0.02)S(0.979)LTADCSLR;LLSS(0.018)S(0.979)LT(0.003)ADCSLR 245.5 4.7680999999999995e-34 17837800.0 56981.0 45471.0 67037.0 102067.0 77959.0 72673.0 60209.0 92945.0 60708.0 85418.0 True False 75099.7727215723 60168.611516130855 66148.04557880234 78537.03006943048 67135.73852029303 68128.74582163591 65567.48435971171 78582.4859136232 63916.90094216167 82427.54181921588 0.9111004776326437 0.7299576111112909 0.8024993117455992 0.9528008276855051 0.8144818714543061 0.8265289042715748 0.7954560200705431 0.953352291955693 0.7754313610655447 1.0 16.330838850537454 -14.522878745228843 0.32323890491964796 2.542254765289744 0.8336240737145263 0.3004139948049619 0.07200820609811802 415.9641093082141 3.6575807917696106 439.5340015186226 0.06161906306480416 3.0000000003557146e-15 14.522878745228843 -1.7086306915752174 LLSSS(ph)LTADCSLR ddPTM_PC-9_Lapatinib_30min_R1 1 LLSSSLTADCSLR 13 0 Q147X3;Q147X3-2 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 LLSS(0.028)S(0.969)LT(0.003)ADCSLR 174.94 0.00017243 7166000.0 20286.0 29804.0 35167.0 28485.0 38843.0 35386.0 28849.0 27931.0 46707.0 43118.0 True False 19996.71792000322 29734.990669152303 32275.705008545672 30579.881923174406 36558.33110827622 33872.623268794894 30342.660060758873 29228.776227128612 41446.36581348549 50570.88884887641 0.39541954620889574 0.5879863167525274 0.6382269670006556 0.6046933842621955 0.7229125676933494 0.6698047837367106 0.6000025064110185 0.5779763198245232 0.8195696527569803 1.0 15.62601951547157 -14.52287874527951 0.10634568546138849 2.2108499014816387 0.3955396523706157 0.7225292704045274 0.08060181898500633 102.29520593185468 0.7268433809849424 27.060451425317826 1.186105215941439 3.000000000005719e-15 14.52287874527951 -1.8153102491110231 LLSSSLTADCS(ph)LRSPSGR ddPTM_PC-9_AZD4547_30min_R2 1 LLSSSLTADCSLRSPSGR 18 1 Q147X3;Q147X3-2 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 LLSSS(0.002)LT(0.063)ADCS(0.884)LRS(0.05)PS(0.002)GR 81.60600000000001 0.014711000000000002 11925000.0 22580.0 14182.0 20572.0 28814.0 23455.0 22276.0 19415.0 19234.0 17227.0 19707.0 True False 29759.970306823332 18766.054155874466 20299.201838493995 22171.377471862295 20198.67811277048 20883.07819854359 21142.897388161324 16261.82725335016 18137.584050382466 19017.06392834396 1.5649087797652939 0.9868008135527495 1.067420392284588 1.1658675364085511 1.062134417220178 1.0981231528289932 1.111785576776072 0.855117662464853 0.9537531197625795 1.0 14.215006903193196 -4.7579439581684495 24.99990276955709 1.0394830038514815 1.5649095164371125 0.7799994593015226 0.08462122988727062 50.00004905194889 357554.4168510811 0.022947486244502005 0.16340995851615792 1.7460474502429192e-05 4.7579439581684495 0.525426512585631 LLSSSLTADCS(ph)LRSPSGR ddPTM_PC-9_Lapatinib_30min_R1 1 LLSSSLTADCSLRSPSGR 18 1 Q147X3;Q147X3-2 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 LLSSS(0.004)LT(0.081)ADCS(0.682)LRS(0.21)PS(0.022)GR 83.964 0.009621 6050500.0 24619.0 16989.0 20533.0 22467.0 25349.0 22858.0 17879.0 15449.0 25877.0 20820.0 True False 24267.928545428345 16949.66301430104 18844.855999672094 24119.298127714927 23858.02165805151 21880.416624600504 18804.68713738112 16166.816939347305 22962.45976310967 24418.709259093837 0.9938251972262072 0.6941260831789776 0.7717384158072987 0.9877384538141627 0.97703860613216 0.8960513183739209 0.7700934123034375 0.6620668098305228 0.9403633713587117 1.0 14.575699322924773 -10.196020664200464 18.12645162350872 0.9999999999999969 0.8481758265740199 0.11839927961610786 0.11764145481668613 0.0 0.0 0.11904227880139728 0.02887199349484631 6.367652222101532e-11 10.196020664200464 -0.15182417342597698 LLSSSLTADCSLRS(ph)PSGR ddPTM_PC-9_AZD4547_30min_R2 2 LLSSSLTADCSLRSPSGR 18 1 Q147X3;Q147X3-2 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 LLSSSLTADCS(0.213)LRS(0.755)PS(0.032)GR;LLSSSLTADCS(0.001)LRS(0.812)PS(0.188)GR 73.346 0.0033679 25606600.0 19055.9 19477.0 34499.0 50289.0 37392.0 27228.0 10052.9 26006.7 23186.2 26960.0 True False 25115.279812656994 25772.559356505906 34041.52071875382 38695.64800730485 32200.766232901897 25525.428855716702 10947.588624952192 21987.962089513443 24411.775196434526 26016.138605985336 0.9653730783429526 0.990637378852856 1.3084770662669418 1.487370919772177 1.2377227351292521 0.9811382558457103 0.42079990388864097 0.8451662417133202 0.9383319933119627 1.0 14.667119228330986 -6.969468478574155 5.175569133669865 0.7761091515236986 1.2035862423123977 0.46247205725099816 0.20092265786809588 0.16825077690541676 11.790901517093602 0.07874403786609896 0.06758116982161792 1.0728315119419088e-07 6.969468478574155 0.4274770907886991 LLSSSLTADCSLRS(ph)PSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLSSSLTADCSLRSPSGR 18 1 Q147X3;Q147X3-2 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 LLSSSLTADCS(0.014)LRS(0.981)PS(0.004)GR;LLSSSLTADCS(0.008)LRS(0.932)PS(0.059)GR 129.05 0.00020351 17137700.0 29005.0 30021.0 37097.0 42495.0 49363.0 39491.0 39579.0 47040.0 40694.0 38543.0 True False 33914.97362513695 33001.2864781229 37981.533171155934 40114.14292064887 39690.67450526046 37420.0224400677 35829.79059285448 45805.24984299986 41289.07276451569 45530.540793779895 0.7448840499994721 0.724816483678387 0.8341990345158549 0.8810381388250283 0.871737383595557 0.8218664173033455 0.7869397105370936 1.0060335116699843 0.9068434515532121 1.0 15.474546974770188 -1.5228787470886171 0.11673508111912598 1.0629066388837705 0.028665582173544403 0.6356097733411681 0.05487469251545991 67.85546722389395 0.5493894143785685 0.445416761479952 11.369284197982859 0.029999999875088473 1.5228787470886171 -1.034241056710226 LLSSSLTADCSLRS(ph)PSGR ddPTM_PC-9_Lapatinib_30min_R1 1 LLSSSLTADCSLRSPSGR 18 1 Q147X3;Q147X3-2 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 LLSSSLTADCS(0.002)LRS(0.99)PS(0.007)GR 140.75 0.00076056 6741200.0 19150.0 15977.0 20075.0 14322.0 20489.0 18760.0 16643.0 15455.0 20655.0 16289.0 True False 18876.91748832011 15940.00623812396 18424.510991740968 15375.287656791435 19283.877302923876 17957.67853169594 17504.693105175575 16173.095721251397 18328.6163932075 19104.53194627182 0.9880858396012088 0.8343573285622731 0.9644052543949627 0.8047979243894465 1.009387581813385 0.9399695623111203 0.9162586738269477 0.8465580714950474 0.9593857857786597 1.0 14.221627292200946 -6.281704672344661 24.979304876183818 0.9358732532516112 0.898121516719704 0.09990593024282002 0.0661138656017918 2373.7003785329753 2925851.716213895 0.019846755633497554 0.022534793454607863 5.22751548129452e-07 6.281704672344661 -0.03775173653190722 LLSSSLTADCSLRSPS(ph)GR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LLSSSLTADCSLRSPSGR 18 1 Q147X3;Q147X3-2 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 LLSSSLTADCSLRS(0.24)PS(0.76)GR 132.5 1.2995e-05 0.0 14279.0 12806.0 13484.0 16611.0 21503.0 19212.0 17969.0 26448.0 17965.0 13939.0 True False 16696.152676894697 14077.295048094396 13805.509698354765 15680.339523588606 17289.64151057706 18204.488899206925 16266.846235705858 25753.76802397237 18227.704138559096 16466.030358936703 1.0139755795988252 0.8549294967414016 0.8384236757380944 0.952284137814572 1.0500188043922412 1.1055784850613188 0.9879033307428138 1.5640544480105905 1.1069883718917273 1.0 14.007205170694299 -6.784110260599939 1.1236233349059674 1.2189121273024492 0.900309152276957 0.3343874790987733 0.15704672544894804 0.48558107381269416 1.2995133816492488 0.08283434962219674 0.07314623576688199 1.6439542958553652e-07 6.784110260599939 -0.3186029750254923 LLST(ph)DAEAVSTR ddPTM_PC-9_AZD4547_30min_R2 1 LLSTDAEAVSTR 12 0 Q15545 Q15545 TAF7 Transcription initiation factor TFIID subunit 7 1 LLS(0.084)T(0.916)DAEAVSTR 193.11 4.552100000000001e-05 8375600.0 3926.7 12086.0 19251.0 19594.0 14699.0 16514.0 16262.0 19195.0 14084.0 12779.0 True False 5175.308919566129 15992.563145388427 18995.719161620058 15076.906024282285 12658.297573208849 15481.376969417703 17709.286496331657 16228.853807219299 14828.451486944143 12331.61109962488 0.4196782462369056 1.2968754055076315 1.540408549066058 1.2226225675200635 1.0264917917816843 1.255422089161459 1.436088630533472 1.3160367835240092 1.2024747915862521 1.0 13.590073676743438 -4.760401783766103 24.99866971677794 1.2714479317687544 0.41967723876918633 0.7201770473453142 0.15593802227251857 13.810130500394353 332566.7342266148 0.039771186181389584 0.2365614149418507 1.7361938608641943e-05 4.760401783766103 -0.8517706929995681 LLST(ph)DAEAVSTR ddPTM_PC-9_Lapatinib_30min_R1 1 LLSTDAEAVSTR 12 0 Q15545 Q15545 TAF7 Transcription initiation factor TFIID subunit 7 1 LLS(0.098)T(0.902)DAEAVSTR 157.33 0.0010192 8152200.0 16024.0 21028.0 14051.0 12294.0 25882.0 20296.0 29412.0 23880.0 26063.0 31848.0 True False 15795.49482155829 20979.310957956466 12895.781018428508 13198.141771581748 24359.67164596983 19427.98739228681 30934.809445978724 24989.55197822602 23127.51048444285 37352.88436520748 0.4228721580674257 0.5616516987774509 0.3452419066849987 0.3533366163250091 0.6521496816095884 0.5201201385771188 0.8281772605168103 0.6690126452859061 0.6191626397126396 1.0 15.188932030829342 -8.183444684754184 0.2462619692828605 1.0815354522925296 0.33102491132585243 0.6865040466950514 0.10983382531434327 1.3259399824926326 0.33293886570955666 0.38934939687540343 0.31635460369055035 6.554737669393104e-09 8.183444684754184 -0.7505105409666771 LLSVS(ph)T(ph)PLPAVT(ph)QT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 LLSVSTPLPAVTQTR 15 0 A0A087X0K0 A0A087X0K0 COL15A1 4 LLS(0.453)VS(0.646)T(0.901)PLPAVT(1)QT(1)R 58.658 0.044994 0.0 3584.0 4390.9 6492.1 8244.6 8371.5 7332.2 4344.6 8059.0 5223.3 5946.7 True False 4723.637448168947 5810.172556270562 6406.010512137217 6343.934847800232 7209.2617276085375 6873.716374903992 4731.260983394576 6813.666727396736 5499.392974421708 5738.507843034607 0.823147336794615 1.012488388130887 1.1163199018561636 1.105502514124903 1.2562955257365607 1.1978229468218466 0.8244758241704548 1.18735861547478 0.9583315253453673 1.0 12.486459933181221 -4.803295181592902 2.67427177779958 1.0892764977017366 0.777594812988428 0.2901127158725889 0.12073919822209057 0.5548253028776604 5.497886097139837 0.03142346530397849 0.38385357270467013 1.5729134221160202e-05 4.803295181592902 -0.3116816847133086 LLT(ph)PTHSFLAR ddPTM_PC-9_AZD4547_30min_R2 2 LLTPTHSFLAR 11 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 LLT(0.999)PT(0.001)HSFLAR;LLT(1)PTHSFLAR 119.21 0.0020702 17493800.0 44935.0 47922.0 56584.0 79808.0 63239.0 54877.0 47862.0 73690.0 50128.0 54867.0 True False 59223.395293937414 63411.84933421352 55833.65918867122 61409.49862130854 54459.35643459785 51445.532514880426 52121.62527902018 62302.90372774115 52777.66374165972 52946.12303021504 1.1185596206947974 1.1976674722344816 1.0545372539705755 1.159848825687646 1.0285806272070053 0.9716581606083174 0.9844276085951688 1.1767226788670895 0.9968182884994397 1.0 15.692237426564775 -6.271177880717757 23.72430320157532 1.0303715161054696 1.1317174456872097 0.4013030727064303 0.06348142431650307 379.51288857485025 924543.0377414153 0.0200136097293429 0.02299984800163854 5.355772479139101e-07 6.271177880717757 0.10134592958174005 LLT(ph)PTHSFLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLTPTHSFLAR 11 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 LLT(0.999)PT(0.001)HSFLAR;LLT(0.999)PT(0.001)HSFLAR 115.37 0.0028643 8779100.0 49141.3 48793.8 52641.0 56315.2 60317.7 48163.2 43734.5 45060.6 40150.3 31221.0 True False 57459.95150508335 53637.72599700987 53896.161082104234 53160.04192034181 48498.87967923242 45637.43700553213 39591.65154963979 43877.80699565217 40737.42218059499 36881.120154699965 1.5579773950483147 1.4543410225075422 1.4613482686001322 1.441389027701951 1.3150056038374405 1.2374200353487987 1.0734937383563825 1.1897091740056756 1.1045603281494583 1.0 15.170594853567492 -6.633466949375897 0.6127283455172825 1.0506039354719672 1.5458263231920233 0.9347707833428031 0.04635989797891144 0.2041842395196307 0.1686093394905766 0.03711478192950706 0.047218580145943954 2.325589460856223e-07 6.633466949375897 0.4952223877200561 LLT(ph)PTHSFLAR ddPTM_PC-9_Lapatinib_30min_R1 2 LLTPTHSFLAR 11 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 LLT(1)PTHSFLAR;LLT(1)PTHSFLAR 138.2 0.00020762 13856800.0 62255.0 59363.0 63773.0 52757.0 50180.0 45046.0 40001.0 35510.0 48548.0 32076.0 True False 61367.23228383125 59225.54862075188 58529.83011089896 56636.925772192815 47228.51105767579 43119.48758735477 42072.056053603825 37159.9242356284 43080.013006896006 37620.293861416605 1.6312268189581984 1.5742978733479176 1.5558047028156574 1.5054886594142125 1.2553998443407528 1.1461762565224973 1.1183340621576843 0.9877627317988508 1.1451269669926447 1.0 15.199223497702228 -6.39910716154042 1.1886197176873825 1.0557126279674436 1.6080885399037161 0.9621073735838154 0.046151208478788175 0.07659337486427112 0.224896701939643 0.019070119831346585 0.024376132263043537 3.989264556861676e-07 6.39910716154042 0.5523759119362726 LLVDADNCLHR ddPTM_PC-9_AZD4547_30min_R2 2 LLVDADNCLHR 11 0 Q9NZB2-4;Q9NZB2;Q9NZB2-6;Q9NZB2-2;Q9NZB2-5 Q9NZB2-4 FAM120A Constitutive coactivator of PPAR-gamma-like protein 1 0 ; 132.17 0.0001022 3597200.0 20578.8 17727.2 23195.0 32171.0 29484.0 26537.0 21547.0 28415.0 19528.7 28623.0 False True 27122.430334369186 23457.170725709882 22887.419144656225 24754.472986995286 25390.65553088574 24877.637194952014 23464.64125793004 24024.114661741954 20560.947213368774 27620.917482163157 0.9819525492548943 0.8492538577278576 0.828626317696952 0.8962219666664244 0.9192546028669156 0.9006810585136182 0.8495243242040339 0.8697797485277626 0.7443976915917612 1.0 14.753473621845735 -7.264698876916655 23.587049996531118 0.8550737515847048 0.8918785365112979 0.03203332485480892 0.06948143918635809 426.1552989804197 3083788.198728501 0.027284326474728317 0.019304933587801016 5.436271309836136e-08 7.264698876916655 0.036804784926593115 LLVDADNCLHR ddPTM_PC-9_Lapatinib_30min_R1 2 LLVDADNCLHR 11 0 Q9NZB2-4;Q9NZB2;Q9NZB2-6;Q9NZB2-2;Q9NZB2-5 Q9NZB2-4 FAM120A Constitutive coactivator of PPAR-gamma-like protein 1 0 ; 128.08 0.00027519999999999997 5789200.0 33061.0 33107.0 34619.0 37072.0 30102.0 32024.0 29697.0 25676.0 38080.0 31628.0 False True 32589.54407735514 33030.342775588026 31772.75945320451 39798.39854856666 28331.45954280903 30654.40817159013 31234.56535146304 26869.000694846352 33791.02939982288 37094.857658339075 0.8785461418269893 0.8904291554320783 0.8565273317893933 1.0728818240826925 0.7637570631421469 0.8263789135931323 0.8420187412268283 0.72433222260407 0.9109356803860527 1.0 15.178931584050153 LLVDSQGLSGCS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 LLVDSQGLSGCSPR 14 0 O94885;A0A087WW74 O94885 SASH1 SAM and SH3 domain-containing protein 1 1 LLVDSQGLSGCS(1)PR;LLVDSQGLSGCS(1)PR;LLVDSQGLS(0.005)GCS(0.995)PR 149.31 6.1806e-05 22309800.0 60708.0 70311.0 100382.0 124257.0 114721.0 101832.0 105092.0 115482.0 96684.0 108610.0 True False 80011.88119515644 93037.65574345579 99050.86909156633 95611.46840151296 98793.96937860365 95464.42894209443 114444.98440981944 97636.91041236251 101794.51885570204 104807.5969583109 0.7634168086783117 0.8876995412886262 0.9450733722190539 0.9122570422022379 0.9426222167645035 0.9108540956250253 1.09195313823808 0.931582378052226 0.9712513387382848 1.0 16.677383768572206 -3.4648516540983483 0.5683263236034393 0.9790533884893222 3.023346201705006e-14 0.635889790941895 0.047939672635044756 10.266051040379299 0.7887714791350786 0.02375444528722132 9.238954466137715 0.00034288488884408493 3.4648516540983483 -0.979053388489292 LLVDSQGLSGCS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LLVDSQGLSGCSPR 14 0 O94885;A0A087WW74 O94885 SASH1 SAM and SH3 domain-containing protein 1 1 LLVDS(0.042)QGLS(0.024)GCS(0.934)PR;LLVDSQGLS(0.001)GCS(0.999)PR 113.65 0.0021743 0.0 35076.0 41781.0 43342.0 51040.0 65523.0 46873.0 49466.0 46947.0 41972.0 38814.0 True False 41013.674017421275 45928.74155899049 44375.43765545032 48180.39427391261 52684.238510791125 44414.89736479939 44780.2223771732 45714.690994458215 42585.76109677718 45850.670948545034 0.8945054274875939 1.0017027146785502 0.9678252626935325 1.0508111065153671 1.1490396415335977 0.9686858762577998 0.9766535898117364 0.9970342864940969 0.9287925392535297 1.0 15.484655224974059 -4.284685713381043 1.6344742446580558 1.0095646648340955 0.6110088889143456 0.24662378276262875 0.057012568162232914 7.020209598528483 5.930569953043377 0.01684127854479037 6.650137537529034 5.191756157074054e-05 4.284685713381043 -0.3985557759197499 LLVDSQGLSGCS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 LLVDSQGLSGCSPR 14 0 O94885;A0A087WW74 O94885 SASH1 SAM and SH3 domain-containing protein 1 1 LLVDSQGLS(0.012)GCS(0.988)PR;LLVDSQGLS(0.004)GCS(0.996)PR;LLVDSQGLSGCS(1)PR;LLVDSQGLS(0.004)GCS(0.996)PR 145.79 0.00012222 28504300.0 85012.0 111052.0 124997.0 108824.0 115529.0 109845.0 88464.0 91607.0 127511.0 72776.0 True False 83799.71329070858 110794.86591701442 114720.22916237336 116827.27998622214 108733.81135875311 105147.18541120151 93044.23306232368 95863.39564779545 113149.36842964325 85355.2346320754 0.9817759115996586 1.2980441843385095 1.3440327316406084 1.3687183977620976 1.2738973986475617 1.2318774105002408 1.0900823301979286 1.123110914767156 1.3256289308719582 1.0 16.381192012546563 -7.074464136669317 5.234742935572077 1.1455105630033584 1.2661665511509694 0.16495362365887334 0.12481471131548307 0.4185756048588511 20.77816003240866 0.048717602393420066 0.037931651753766026 8.424339553895115e-08 7.074464136669317 0.12065598814761103 LLVDVDESTLS(ph)PEEQKER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LLVDVDESTLSPEEQKER 18 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 LLVDVDES(0.009)T(0.032)LS(0.959)PEEQKER;LLVDVDES(0.048)T(0.306)LS(0.646)PEEQKER;LLVDVDES(0.033)T(0.029)LS(0.939)PEEQKER 67.251 0.0062092 15753700.0 46429.0 42148.0 48357.0 53629.0 60464.3 51626.2 60641.6 46465.5 49864.8 35609.0 True False 54288.51268545024 46332.174893571995 49510.01427494376 50624.34099756386 48616.75446160929 48918.83118926906 54897.188640835884 45245.82985926681 50593.97836506659 42064.62981931109 1.2905976569542372 1.1014521010310128 1.1769986919560298 1.203489516370905 1.155763278327728 1.1629445308184154 1.3050676750668468 1.07562648366622 1.2027677072731502 1.0 15.36032002775903 -9.840529723892624 0.7036847112853483 0.9879171816897523 1.1863242617659353 0.40013259828555103 0.06828227380497225 9.774523541524081 4.095472795370553 0.39237183658434477 0.023421534416642503 1.44367779301405e-10 9.840529723892624 0.19840708007618302 LLVDVDESTLS(ph)PEEQKER ddPTM_PC-9_Lapatinib_30min_R1 2 LLVDVDESTLSPEEQKER 18 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 LLVDVDES(0.04)T(0.035)LS(0.925)PEEQKER;LLVDVDES(0.099)T(0.204)LS(0.697)PEEQKER 58.093 0.015343 16707600.0 36798.0 34717.0 36367.0 30527.0 34261.0 35486.0 38743.0 32556.0 39460.0 32376.0 True False 36273.25377207329 34636.61491950612 33377.04564067963 32772.05741508672 32245.83533971764 33968.346501906264 40748.92296904507 34068.6706115212 35015.59926777862 37972.14846169174 0.9552594530875075 0.9121584193332997 0.8789875472638088 0.8630551270531575 0.8491970206070616 0.8945595094829908 1.0731266104195996 0.8972015540782854 0.9221390067803028 1.0 15.212654008407418 -7.043755930772856 24.993523550938825 0.9673063928862986 0.8886964410816325 0.36949736174376746 0.0514923434994049 544.4885304653671 311011.9157312867 0.02016477455686764 0.015620579401326481 9.041574585661826e-08 7.043755930772856 -0.07860995180466612 LLVVTDPR ddPTM_PC-9_Lapatinib_30min_R1 2 LLVVTDPR 8 0 C9J9K3;A0A0C4DG17;P08865 C9J9K3 RPSA 40S ribosomal protein SA 0 ; 111.04 0.017289 25889000.0 223930.0 223888.0 218374.0 214220.0 235337.0 231844.0 223582.0 216660.0 218591.0 202482.0 False True 220736.7171362675 223369.60109163792 200420.13266801738 229974.45341697117 221494.94035034376 221928.57257476097 235157.98196487236 226726.81455621638 193970.97971472357 237480.74390969487 0.9294931180618397 0.9405798441349716 0.8439426682284175 0.9683920036246052 0.9326858957228553 0.9345118636614689 0.9902191566921074 0.9547166259611861 0.8167861381994136 1.0 17.857451011913007 LLYNNVSNFGR ddPTM_PC-9_Lapatinib_30min_R1 1 LLYNNVSNFGR 11 0 A0A087WVQ6;Q00610-2;Q00610;J3KS13 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 135.55 0.00033474 2960600.0 12098.0 13118.0 10043.0 9279.3 10382.0 10099.0 11293.0 10263.0 10515.0 10037.0 False True 11925.480301498523 13087.626076967512 9217.303307101101 9961.730676837366 9771.35117179734 9667.089311918833 11877.696282926627 10739.856446923517 9330.689972141212 11771.882076538166 1.0130478902151496 1.1117700629240652 0.7829931736635009 0.846230926547548 0.830058533399008 0.8212016777831754 1.008988724632177 0.9123312973316716 0.7926251649035503 1.0 13.523057374982724 -5.254208455650647 24.987652334051198 0.8715035584063361 1.0624089884584753 0.4815022813645208 0.0780359043582729 457.15413009188364 1579761.5396046152 0.020047635362834503 0.05081643920408715 5.569183712602325e-06 5.254208455650647 0.19090543005213922 LMEDLDR ddPTM_PC-9_Lapatinib_30min_R1 2 LMEDLDR 7 0 R4GN98;P06703 R4GN98 S100A6 Protein S100;Protein S100-A6 0 ; 108.09 0.045207 52699000.0 112518.0 136595.0 156191.0 141809.0 160291.0 155634.0 145199.0 145996.0 159002.0 122868.0 False True 110913.472686726 136278.7226698719 143349.57889469538 152238.10692095643 150862.9985242312 148977.896620574 152716.6937558366 152779.50714460172 141093.52039471196 144105.57008868078 0.7696681857507051 0.9456867113881002 0.9947539071978955 1.056434576590419 1.04689220847877 1.0338108133425714 1.059755661504664 1.0601915460351956 0.9790983117993618 1.0 17.136766575279168 -4.523356626079829 1.282964034146971 1.0375040990939033 0.5025870911811576 0.8990126787138605 0.026568670847316147 0.6635625831845573 0.6244122314259615 0.00766986739493245 0.5471061354964115 2.9967007319107918e-05 4.523356626079829 -0.5349170079127457 LMELHGEGS(ph)SSGK ddPTM_PC-9_AZD4547_30min_R2 2 LMELHGEGSSSGK 13 0 D6RAT0;P61247;D6RG13;D6R9B6;H0Y9Y4 D6RAT0 RPS3A 40S ribosomal protein S3a 1 LMELHGEGS(0.376)S(0.376)S(0.248)GK;LMELHGEGS(0.333)S(0.333)S(0.333)GK 71.286 0.018201 11232000.0 60336.0 70523.0 112849.0 112929.0 100083.0 108812.0 84902.0 111745.0 91041.0 104216.0 True False 79521.59293323707 93318.18059756981 111352.54852577334 86894.96378565754 86188.20300833139 102007.96843867496 92458.1135230323 94477.37789464579 95853.2413961148 100567.4295608818 0.7907290986799663 0.9279165332656392 1.107242663076741 0.8640467810013263 0.857019050647551 1.0143241095460342 0.9193643899097543 0.9394431010832468 0.953124106031634 1.0 16.617803614378523 -4.78300040862145 4.857465181537109 0.952527890283853 0.7825557053570698 0.33480214320020174 0.06954286518924617 0.19754462508192697 11.14628288027876 0.017520891169186148 0.10931298639525061 1.6481608407938792e-05 4.78300040862145 -0.16997218492678323 LMELHGEGS(ph)SSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LMELHGEGSSSGK 13 0 D6RAT0;P61247;D6RG13;D6R9B6;H0Y9Y4 D6RAT0 RPS3A 40S ribosomal protein S3a 1 LMELHGEGS(0.441)S(0.441)S(0.117)GK;LMELHGEGS(0.473)S(0.473)S(0.054)GK 65.477 0.027497000000000004 10116700.0 72260.0 76921.0 88867.0 87446.0 109435.0 86347.0 94631.0 82204.0 80964.0 65353.0 True False 84492.19079994473 84557.20852682106 90985.92630997446 82546.68412375709 87991.99733572063 81818.81131479381 85666.86661089008 80046.2321023377 82147.94533116058 77200.9815659366 1.0944445146436483 1.0952867024702475 1.1785591901090566 1.0692439713769024 1.1397782197959172 1.0598156869924402 1.1096603290946871 1.0368551082989923 1.0640790267802336 1.0 16.236331570194444 -8.125862016862904 0.5593362659306166 1.001040590999548 1.117644096881406 0.5185157031775075 0.03358009688831541 0.6078827640048626 0.4539484709964969 0.03249689857429743 0.017015490358431775 7.484072451304585e-09 8.125862016862904 0.1166035058818582 LMELHGEGS(ph)SSGK ddPTM_PC-9_Lapatinib_30min_R1 1 LMELHGEGSSSGK 13 0 D6RAT0;P61247;D6RG13;D6R9B6;H0Y9Y4 D6RAT0 RPS3A 40S ribosomal protein S3a 1 LMELHGEGS(0.726)S(0.239)S(0.036)GK 67.29899999999999 0.043848000000000005 0.0 53443.0 48249.0 56117.0 52786.0 66337.0 66566.0 48280.0 48455.0 59945.0 38341.0 True False 52680.89301975409 48137.28240490972 51503.27687788431 56668.05852893401 62435.18808356004 63719.12735292492 50779.7021641457 50706.39619367425 53193.362851165475 44968.19076382883 1.1715146223345312 1.0704740748349169 1.1453268633460816 1.2601809760715619 1.3884300662988018 1.4169822327870665 1.1292360511197503 1.1276058772295787 1.1829108965164936 1.0 15.456617219781423 -8.624781033184 1.0047691122856213 1.006193589060426 1.22775452345499 0.2774914851946084 0.10622505281655302 1.0307613252798016 2.220497597007224 0.11685265472183944 0.0384370088353187 2.3725696293823546e-09 8.624781033184 0.22156093439456392 LMELHGEGSS(ph)SGK ddPTM_PC-9_AZD4547_30min_R2 1 LMELHGEGSSSGK 13 0 D6RAT0;P61247;D6RG13;D6R9B6;H0Y9Y4 D6RAT0 RPS3A 40S ribosomal protein S3a 1 LMELHGEGS(0.357)S(0.596)S(0.047)GK 79.347 0.009692399999999999 9305200.0 38261.0 48562.0 64770.0 67903.0 57054.0 55658.0 53835.0 61356.0 54608.0 56525.0 True False 50427.20212176121 64258.71681833135 63911.107480033825 52249.01244089217 49133.036923726606 52177.69646141767 58626.21070778595 51874.840020617245 57494.467395558415 54546.07695487096 0.9244881563798342 1.1780630323147934 1.1716902671646043 0.9578876311145295 0.9007620651504806 0.9565801864098717 1.074801598587754 0.9510278816849875 1.054053207953467 1.0 15.735187818788019 -5.776250791603707 24.994763298259368 0.9820212133159115 1.1000787510089831 0.26554630612058827 0.08059478459188164 280.34320326322575 473087.96128272486 0.02291597124482048 0.034150976991934506 1.6739759276433529e-06 5.776250791603707 0.11805753769307159 LMELHGEGSS(ph)SGK ddPTM_PC-9_Lapatinib_30min_R1 1 LMELHGEGSSSGK 13 0 D6RAT0;P61247;D6RG13;D6R9B6;H0Y9Y4 D6RAT0 RPS3A 40S ribosomal protein S3a 1 LMELHGEGS(0.136)S(0.432)S(0.432)GK 73.758 0.032527999999999994 0.0 20387.0 24029.0 26686.0 24497.0 26114.0 27284.0 19925.0 22919.0 26118.0 18763.0 True False 20096.27764148208 23973.362326837356 24491.980090938952 26298.59109959642 24578.02586209937 26117.126922110434 20956.619006226258 23983.900409923044 23176.31580526716 22006.15954987405 0.9132114849906693 1.089393279754466 1.1129602162263306 1.195055913322547 1.1168702929012455 1.1868098503475548 0.9523069647264373 1.0898721494573693 1.0531740330583856 1.0 14.425619771858074 -7.261734726361636 24.999999697310685 1.0313276366967241 1.1071446713090711 0.18590902776111606 0.07953549370687854 51.36126596211736 4347225.635983731 0.032932219970218085 0.02375760964408238 5.4735019058313854e-08 7.261734726361636 0.07581703461234701 LMELHGEGSSSGK ddPTM_PC-9_Lapatinib_30min_R1 2 LMELHGEGSSSGK 13 0 D6RAT0;P61247;D6RG13;D6R9B6;H0Y9Y4 D6RAT0 RPS3A 40S ribosomal protein S3a 0 ; 77.279 0.011058 4073600.0 48880.0 39357.0 80613.0 41416.0 50471.0 60575.0 41920.0 36121.0 73120.0 39376.0 False True 48182.96223650583 39265.87128458686 73985.31031517882 44461.87079972586 47502.39500980384 57984.34845722181 44090.412483864675 37799.313526193575 64884.455612264916 46182.08913477804 1.0433257381641707 0.8502402559137838 1.602034721713427 0.9627513963252747 1.0285891327084102 1.255559233970555 0.9547080547870191 0.8184842702953491 1.4049701264684193 1.0 15.495045817196154 -7.28840159945331 24.75494152365674 1.0294143276804817 1.1214144571494342 0.024819446976876325 0.2354558054884324 2977.942074241409 2734136.7082451317 0.09745879803439443 0.06573099505652627 5.1475242415772886e-08 7.28840159945331 0.09200012946895253 LMET(ph)QQEEET(ph)EKK ddPTM_PC-9_Lapatinib_30min_R1 1 LMETQQEEETEKK 13 1 Q13370-2;Q13370 Q13370-2 PDE3B cGMP-inhibited 3,5-cyclic phosphodiesterase B 2 LMET(1)QQEEET(1)EKK 62.287 0.033032 0.0 16508.0 8273.6 12763.0 13492.0 13438.0 19499.0 21855.0 13107.0 17901.0 16318.0 True False 16272.592892803561 8254.442987528475 11713.675406604727 14484.246687992594 12647.603260124504 18665.07322438908 22986.544962663706 13715.999069455967 15884.800874113158 19138.544557631736 0.8502523712710777 0.4312994106041837 0.6120463011871898 0.7568102498273213 0.6608445706014313 0.9752608495480471 1.2010602422480203 0.7166688683224106 0.8299900144590093 1.0 14.224193499899725 -6.756347832915754 24.37619133279217 0.9429168371749412 0.6518840736242743 0.457609226574228 0.1534821416537574 87.86016301019649 420637.17766466184 0.05324697183246419 0.05165992031615067 1.7524763552144273e-07 6.756347832915754 -0.291032763550667 LMHNAS(ph)DSEVDQDDVVEWK ddPTM_PC-9_AZD4547_30min_R2 1 LMHNASDSEVDQDDVVEWK 19 0 Q9H2P0;A0A669KBJ7;A0A2R8Y6X0 Q9H2P0 ADNP Activity-dependent neuroprotector homeobox protein 1 LMHNAS(0.563)DS(0.437)EVDQDDVVEWK 62.203 0.041799 0.0 11833.0 13043.0 20457.0 24354.0 20306.0 17256.0 15410.0 23152.0 14056.0 19310.0 True False 15595.64785831004 17258.894680233432 20185.726813633657 18739.561565549197 17486.862407073877 16176.979592120131 16781.460146874368 19574.39038003342 14798.971464107262 18633.96277750656 0.836947462250803 0.9262063516122828 1.0832761154809358 1.0056670064925808 0.938440342286324 0.868144891415566 0.9005846124760759 1.0504684705961778 0.79419346495483 1.0 14.185646896099778 -6.511241890592666 23.807092989855914 0.9221007065057101 0.9693675459484707 0.043546624824423175 0.08716180231261238 998.128054492107 2042013.7606169158 0.028246674812175937 0.030285779101877873 3.081471173876746e-07 6.511241890592666 0.047266839442760666 LMIEMDGTENK ddPTM_PC-9_Lapatinib_30min_R1 1 LMIEMDGTENK 11 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879 P06733 ENO1 Alpha-enolase;Enolase 0 147.75 0.0012205 11551000.0 43388.0 42328.0 44506.0 42416.0 34827.0 43384.0 41085.0 34841.0 37752.0 36587.0 False True 42769.27916361529 42229.99211662459 40846.88847812819 45535.414135628096 32778.54433251646 41528.567453043506 43212.1802695511 36459.8400533238 33499.972213816 42911.014200886944 0.9966970009935415 0.9841294339706314 0.9518975311770633 1.061159121582517 0.7638725148528172 0.9677834054126163 1.0070183861713045 0.8496615783220104 0.780684699200691 1.0 15.389060379104608 -6.233069809740461 24.998986087631042 0.8965762090164396 0.9941197197509317 0.2753461956506674 0.08221312467485642 1091.4248013649344 961752.5569372905 0.024681193042159474 0.03185757278849311 5.846960908639118e-07 6.233069809740461 0.09754351073449208 LMLS(ph)TSEYSQSPK ddPTM_PC-9_AZD4547_30min_R2 1 LMLSTSEYSQSPK 13 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 LMLS(0.869)T(0.121)S(0.003)EYS(0.004)QS(0.003)PK 106.54 0.0011068 9006100.0 32707.0 32931.0 33184.0 45716.0 41101.0 45046.0 40163.0 34348.0 33689.0 37396.0 True False 43107.145652137755 43575.30174919629 32743.95847795958 35176.882505159156 35394.83560490213 42229.26649899422 43737.42919395945 29040.305838518827 35469.731762543386 36086.777422456515 1.1945412899438486 1.2075143546090021 0.907367208067276 0.9747859193231497 0.9808256135078497 1.1702143974960557 1.212007065134666 0.8047353605048501 0.9829010595019453 1.0 15.139182694737404 -5.241804028188098 23.85554445839286 1.0086099390542906 1.20102792456229 0.3364699285816488 0.1104701765083493 571.9358886083329 694855.6924407118 0.030199557021452286 0.07960482216480896 5.730545588071546e-06 5.241804028188098 0.19241798550799927 LMLSTSEYS(ph)QSPK ddPTM_PC-9_Lapatinib_30min_R1 1 LMLSTSEYSQSPK 13 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 LMLS(0.04)T(0.187)S(0.052)EY(0.038)S(0.677)QS(0.006)PK 72.607 0.0232 8520400.0 10375.0 14536.0 13924.0 11099.0 10767.0 12372.0 10152.0 9564.0 12656.0 12025.0 True False 10227.050597458023 14502.342785089182 12779.222468194337 11915.257485178612 10133.706228736462 11842.87840054063 10677.620885882501 10008.378355098563 11230.548006411716 14103.505227694684 0.7251424686520789 1.0282793214137511 0.9061025795984471 0.8448436961459008 0.7185239460072074 0.8397117035334648 0.7570898662068162 0.7096376534427322 0.7962948093470114 1.0 13.78376614828276 -5.985048598803701 4.8618742110998445 0.787702989636029 0.8985423756682924 0.1003777640039808 0.10330046927754749 0.30251478427187983 19.454373789273774 0.02842568062506974 0.04122304731993364 1.0350263377696264e-06 5.985048598803701 0.1108393860322634 LMLSTSEYSQS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LMLSTSEYSQSPK 13 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 LMLSTSEYS(0.002)QS(0.998)PK 111.83 0.00046004 11341000.0 34220.0 35667.0 30559.0 40638.0 50088.0 39722.0 45657.0 39284.0 34677.0 37456.0 True False 40012.7701241919 39207.784045008826 31287.642455652855 38361.184610173616 40273.61595971654 37638.90839341545 41332.03843194513 38252.83662483855 35184.08552256131 44246.476298467125 0.9043154047857614 0.8861221802281042 0.7071216755115205 0.8669884659606804 0.9102106953794143 0.8506645396917044 0.9341317521679583 0.8645397289221827 0.7951838986052824 1.0 15.43327494595081 -5.988106526092659 24.99183430361735 0.8859421550100991 0.8294091938483776 0.12246964823126161 0.07045677172748348 505.44837232943644 1062091.8689749977 0.019784997787200546 0.029321279205428326 1.0277641716675385e-06 5.988106526092659 -0.05653296116172146 LMLSTSEYSQS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 LMLSTSEYSQSPK 13 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 LMLSTSEYS(0.002)QS(0.998)PK;LMLSTSEYSQS(1)PK 222.56 7.822499999999999e-16 17120200.0 77953.0 62279.0 54157.0 53970.0 69064.0 58228.0 57786.0 59716.0 55922.0 46565.0 True False 76841.37592517042 62134.79680191039 49704.42051206553 57939.13383864219 65001.7913050482 55737.724176097574 60777.876330930456 62490.62336397592 49623.47547523354 54613.698206037654 1.4069982156358614 1.1377145083180114 0.9101090412253131 1.0608901382224452 1.1902103948320812 1.0205813927088287 1.1128687184236745 1.1442298437330043 0.908626903236294 1.0 15.736975232806635 -4.80634063927825 3.6954442214942573 1.0544657835271636 1.4354098775394515 0.6062810161130696 0.08768608831208306 0.1679819506052999 3.95955905337735 0.02199759161938447 0.16819389561309692 1.5619220670463138e-05 4.80634063927825 0.3809440940122879 LMPS(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 1 LMPSPLK 7 0 Q8NI77 Q8NI77 KIF18A Kinesin-like protein KIF18A 1 LMPS(1)PLK 70.816 0.043012 3997800.0 47105.0 58293.0 60292.0 64095.0 63893.0 61499.0 61963.0 66638.0 59801.0 79817.0 True False 62083.41015513346 77135.07226825476 59492.488685906996 49318.88800787858 55022.559823459625 57653.45780805493 67477.58696176352 56340.628288902364 62961.95877383881 77022.63112440406 0.8060411498389177 1.0014598455312322 0.7724027057686067 0.6403168430875928 0.7143687383853359 0.7485262054335075 0.8760748104381978 0.7314814810455268 0.8174475197055397 1.0 16.232994786575468 -9.952885667248971 12.228467924594831 0.9999999521776779 0.7885007474112734 0.31430408008190813 0.09312824881928826 0.0 0.0 0.09748806954877082 0.023644329881596635 1.1145879223775174e-10 9.952885667248971 -0.2114992047664045 LMPS(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 1 LMPSPLK 7 0 Q8NI77 Q8NI77 KIF18A Kinesin-like protein KIF18A 1 LMPS(1)PLK 74.165 0.034581 3664900.0 33300.0 55967.0 53828.0 47801.0 66771.0 60433.0 56017.0 58321.0 51230.0 58637.0 True False 32825.1358935279 55837.4118501022 49402.46962208878 51316.44499946148 62843.66105683679 57848.42146620362 58917.28616671393 61030.80657127808 45459.93792418398 68772.32732110869 0.4773015131545895 0.8119168570432209 0.7183480848542607 0.7461786884113578 0.9137928510607175 0.8411584094878793 0.8567004849438926 0.8874326193196248 0.6610207869209436 1.0 16.06954054814392 -4.354653705246618 1.202657711834382 0.8353209175222561 3.159299557322332e-63 0.5374495202626293 0.09567959606334672 2.9896577560186066 1.847410404409422 0.027609735525981362 4.000047049166762 4.419226841795179e-05 4.354653705246618 -0.8353209175222561 LMSLLTSPHQPPPPPPAS(ph)ASPSAVPNGPQSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LMSLLTSPHQPPPPPPASASPSAVPNGPQSPK 32 0 Q96RU3-5;Q96RU3-2;Q96RU3 Q96RU3-5 FNBP1 Formin-binding protein 1 1 LMSLLTSPHQPPPPPPAS(0.274)AS(0.274)PS(0.274)AVPNGPQS(0.179)PK;LMSLLTSPHQPPPPPPAS(0.478)AS(0.061)PS(0.055)AVPNGPQS(0.405)PK 70.465 2.1272e-05 14286100.0 18862.6 25606.0 33660.0 42035.0 51118.0 48144.0 62789.0 55387.0 42078.0 40501.0 True False 22055.665626668095 28147.99445584142 34462.58205626086 39679.915229308725 41101.79485363339 45619.24388733182 56841.17136700623 53933.1499373774 42693.3111462449 47843.51069426041 0.46099597012461757 0.5883346361373565 0.7203188385670701 0.8293688037000378 0.8590881868241372 0.9535095402772057 1.1880643903881667 1.1272824496938 0.8923532267327248 1.0 15.546035636045513 -5.598017218634038 0.6699675036704258 1.0617520700049183 0.3780929275189015 0.8483924273073893 0.08368026768460882 0.517435159172428 0.34839422503368284 0.04740726631780613 0.23358576365898842 2.5233807250878785e-06 5.598017218634038 -0.6836591424860168 down LMSLLTSPHQPPPPPPASASPSAVPNGPQS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 LMSLLTSPHQPPPPPPASASPSAVPNGPQSPK 32 0 Q96RU3-5;Q96RU3-2;Q96RU3 Q96RU3-5 FNBP1 Formin-binding protein 1 1 LMSLLTSPHQPPPPPPAS(0.004)AS(0.004)PS(0.001)AVPNGPQS(0.991)PK 123.68 5.6069000000000006e-18 6561600.0 7014.1 8678.8 21894.0 32947.0 27071.0 25140.0 18235.0 30454.0 23389.0 23468.0 True False 9244.437897656753 11484.052376815906 21603.671254714543 25351.578176075767 23312.65892947388 23567.99182579394 19857.879674124215 25748.034063300693 24625.294790410135 22646.39246310326 0.4082079701090713 0.5071029478768573 0.9539564100512885 1.1194532735127656 1.029420423913263 1.040695195236601 0.8768672408410195 1.1369596329857303 1.0873826738864043 1.0 14.46699362893313 -5.260793913361413 3.1605315415151227 1.0405204008508853 0.42391465412229085 0.9191753489009832 0.06864922809839592 0.062038086409269465 1.269044569037082 0.01889160544581511 0.0544696790242303 5.485372016380102e-06 5.260793913361413 -0.6166057467285944 down LMSLLTSPHQPPPPPPASASPSAVPNGPQS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LMSLLTSPHQPPPPPPASASPSAVPNGPQSPK 32 0 Q96RU3-5;Q96RU3-2;Q96RU3 Q96RU3-5 FNBP1 Formin-binding protein 1 1 LMSLLTSPHQPPPPPPAS(0.024)AS(0.002)PS(0.019)AVPNGPQS(0.955)PK 76.936 4.1351999999999996e-07 6258800.0 11126.0 21368.0 21994.0 35299.0 31508.0 34785.0 34390.0 33826.0 37840.0 19718.0 True False 13009.412051483318 23489.273823807685 22518.4203727095 33321.31147090208 25334.23358207051 32960.81336450724 31132.330237961152 32938.10334160952 38393.338413753205 23292.717312397883 0.5585184363422842 1.008438539341444 0.966757981505393 1.430546338754832 1.0876461188401578 1.4150694795477285 1.3365692727224454 1.4140944957108008 1.6482979593504876 1.0 14.50759133272833 -4.629651031060218 0.69481865759722 1.3741024776255284 3.585771463613749e-14 0.6163905235787646 0.18768692214771304 2.3307438761777535 0.7370403106201003 0.07664172201655191 2.6499469123647623 2.3461132320827775e-05 4.629651031060218 -1.3741024776254926 LMSLLTSPHQPPPPPPASASPSAVPNGPQS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 LMSLLTSPHQPPPPPPASASPSAVPNGPQSPK 32 0 Q96RU3-5;Q96RU3-2;Q96RU3 Q96RU3-5 FNBP1 Formin-binding protein 1 1 LMSLLTSPHQPPPPPPAS(0.001)AS(0.001)PSAVPNGPQS(0.997)PK;LMSLLTSPHQPPPPPPAS(0.036)AS(0.036)PS(0.186)AVPNGPQS(0.742)PK;LMSLLTSPHQPPPPPPAS(0.002)AS(0.002)PS(0.013)AVPNGPQS(0.983)PK 128.06 1.124e-17 9399900.0 46580.6 35096.9 46383.4 35082.600000000006 49917.0 47682.8 44967.4 48118.4 56691.0 36686.3 True False 45916.352102164165 35015.63528439709 42569.93589710175 37662.69143612282 46980.98020059792 45643.51779803577 47295.59194482196 50354.15652885559 50305.86259730458 43027.47807357801 1.0671402126716818 0.8137970629958726 0.9893662794808971 0.8753171954842142 1.0918831942755123 1.0607992808684783 1.0991950739930743 1.1702790584832508 1.1691566610360096 1.0 15.392970663076051 -6.318929039320019 7.087319965731379 1.1059092845031513 0.9315988090089187 0.5095160173958139 0.07769526969952055 0.1963394734450569 20.86364699724165 0.023277712079945348 0.026508366877279 4.798118401300758e-07 6.318929039320019 -0.17431047549423262 LMWSQPDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LMWSQPDDR 9 0 Q96DU9-2;Q96DU9 Q96DU9-2 PABPC5 Polyadenylate-binding protein 5 0 108.09 0.0039162 0.0 53306.0 40698.0 34825.0 47194.0 43903.0 39123.0 57765.0 50718.0 47442.0 34544.0 False True 62329.65295850891 44738.228476288146 35655.36007454795 44549.87318501238 35300.522310322514 37071.32100789469 52293.08101761637 49386.706240162996 48135.749498553894 40806.55374984644 1.5274422177526683 1.0963490999642798 0.873765530241135 1.091733290150238 0.8650699230011638 0.9084648812823158 1.281487315449008 1.210264080199344 1.1796083000205582 1.0 15.316513254861302 -10.465202779686809 15.214454155936606 0.9999718742850648 1.1008731774844005 0.02611449056250814 0.19417883983154685 0.0 0.0 0.19634157006774858 0.04761982541699638 3.426077796318769e-11 10.465202779686809 0.10090130319933566 LNAS(ph)PAAR ddPTM_PC-9_Lapatinib_30min_R1 1 LNASPAAR 8 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 LNAS(1)PAAR 97.59700000000001 0.0057644 9579300.0 28816.0 45242.0 46988.0 34343.0 37040.0 34682.0 38821.0 41220.0 43279.0 42028.0 True False 28405.07855579281 45137.24492866018 43124.82801892525 36868.698784889566 34861.38002344187 33198.731707690764 40830.96142738818 43135.23168100825 38404.463271925786 49292.48380121016 0.5762557770540961 0.9157023839718141 0.8748763440860837 0.7479578211878302 0.7072352077861006 0.6735049473582363 0.8283405152001238 0.875087403892381 0.779113980679199 1.0 15.589080058416286 -9.146513746059695 0.6369900491419255 1.0053269865386274 0.7663923679078406 0.33721508033354464 0.0974218799992086 2.741417906772045 1.7219867259916546 0.14130538010013002 0.040217973329569306 7.136516166407348e-10 9.146513746059695 -0.2389346186307868 LNATAS(ph)LEQER ddPTM_PC-9_AZD4547_30min_R2 2 LNATASLEQER 11 0 A0A669KAX3;O76024 A0A669KAX3 WFS1 Wolframin 1 LNAT(0.029)AS(0.971)LEQER;LNAT(0.008)AS(0.992)LEQER 99.844 0.0043936999999999995 7493100.0 16267.7 17814.8 30916.8 34246.0 33503.0 21221.4 22618.0 30996.5 21648.6 20956.2 True False 21440.490210819768 23573.085712598513 30506.823031321746 26351.11379542571 28851.686753875485 19894.42250325791 24630.958183128125 26206.7031537105 22792.900799507162 20222.52981657084 1.0602278945956058 1.1656843098474328 1.50855621467912 1.3030572353926242 1.4267100612819321 0.9837751598692626 1.217995889067495 1.295916158434148 1.1271043240509946 1.0 14.30367586766681 -6.752603001073128 24.999983980564014 1.1492679044960825 1.2983335761062698 0.24166592087260386 0.14538771056715852 337.9900794706641 956244.3648719803 0.050498251300563235 0.04977452045754676 1.7676529360043083e-07 6.752603001073128 0.14906567161018724 LNATAS(ph)LEQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LNATASLEQER 11 0 A0A669KAX3;O76024 A0A669KAX3 WFS1 Wolframin 1 LNAT(0.038)AS(0.962)LEQER 70.27199999999999 0.032635000000000004 2999200.0 6617.8 8180.3 6975.2 7472.7 10824.0 5389.5 3226.6 1229.8 2591.3 2528.0 True False 7738.062832492033 8992.386122280692 7141.515221593309 7054.028845820273 8703.114900734134 5106.865132327492 2920.9530894389486 1197.5190530808084 2629.192860242037 2986.3063883630093 2.591181823353957 3.0112068062815247 2.3914208031105755 2.362124955867991 2.9143409178134876 1.7100941658993336 0.9781156752104444 0.4010034126931119 0.8804163131041857 1.0 11.5441464750159 -7.066171280954276 2.3841818633675858 0.7375483980483529 2.6455907377958066 0.919802022423822 0.2552058616766428 0.07584708687258494 0.8520917131616488 0.11041039413075163 0.08369479043147593 8.586748028435332e-08 7.066171280954276 1.9080423397474537 up LNATAS(ph)LEQER ddPTM_PC-9_Lapatinib_30min_R1 2 LNATASLEQER 11 0 A0A669KAX3;O76024 A0A669KAX3 WFS1 Wolframin 1 LNAT(0.033)AS(0.967)LEQER;LNAT(0.032)AS(0.968)LEQER 88.22399999999999 0.009944 6382800.0 19717.9 27803.0 21303.0 12078.0 17744.4 18291.0 21195.3 19514.8 25415.0 19281.6 True False 19436.71913017999 27738.623861711225 19551.54957195804 12966.256411026872 16700.70927883265 17508.736568403532 22292.688924600618 20421.528850279938 22552.495068185362 22614.39886888296 0.8594842269685353 1.2265912537643933 0.864561984836159 0.5733628599285134 0.7384989260896319 0.7742295813352468 0.9857741102848854 0.9030321331414927 0.9972626377974266 1.0 14.464954026617253 -7.275738279353926 23.493891967019962 0.9634365815869165 0.8415091583881793 0.1461787230203223 0.1558241332692287 939.4480566171999 1543555.433109095 0.07360499853027878 0.04994542577545465 5.299827333199979e-08 7.275738279353926 -0.12192742319873717 LNCS(ph)TSPEIFR ddPTM_PC-9_AZD4547_30min_R2 2 LNCSTSPEIFR 11 0 Q9BRS8 Q9BRS8 LARP6 La-related protein 6 1 LNCS(0.333)T(0.333)S(0.333)PEIFR;LNCS(0.333)T(0.333)S(0.333)PEIFR 110.64 0.0019117000000000001 15454700.0 32865.0 44690.0 71209.0 85928.0 76608.0 78405.0 86877.0 106344.0 77272.0 84386.0 True False 43315.38636553363 59135.16853941824 70264.72213286601 66118.62717436597 65972.30155033557 73502.32295550416 94608.88469695022 89910.97834201249 81356.44016608551 81431.67182509949 0.5319230883355466 0.7261937181693862 0.8628672426593664 0.8119522256202333 0.8101553126900323 0.9026257389554013 1.1618192599576367 1.104127869744895 0.9990761376092638 1.0 16.31330240128959 -4.700969115258372 0.37192425119339806 1.0840059813463863 0.1625270146410291 0.776894735399958 0.0834501385266206 3.3080168316832883 0.348148864008751 0.08326805736790341 1.3917517045819394 1.9908149102492488e-05 4.700969115258372 -0.9214789667053571 LNCST(ph)SPEIFR ddPTM_PC-9_Lapatinib_30min_R1 2 LNCSTSPEIFR 11 0 Q9BRS8 Q9BRS8 LARP6 La-related protein 6 1 LNCS(0.098)T(0.451)S(0.451)PEIFR;LNCS(0.22)T(0.39)S(0.39)PEIFR 102.33 0.0082235 15258500.0 50900.0 67786.0 82255.0 66682.0 59429.0 64749.0 51647.0 68374.0 58276.0 43649.0 True False 50174.15666608322 67629.04568175938 75492.3114134822 71586.01672463091 55933.503061909425 61979.83620729101 54321.02894928817 71550.90565155876 51712.34320651464 51193.67149136343 0.9800851395186179 1.3210430842642076 1.4746414784143396 1.3983372287863307 1.0925862793674728 1.2106933220788285 1.061088751144804 1.3976513808670603 1.0101315592345963 1.0 15.643677856330775 -6.2688144752034365 24.936764999084886 1.149294365310442 1.3084289551422255 0.19092311687824293 0.1617964964492842 981.5667158504605 3318879.29801476 0.05006424004673838 0.05792171929009087 5.384997732922173e-07 6.2688144752034365 0.15913458983178352 LNCST(ph)SPEIFRK ddPTM_PC-9_Lapatinib_30min_R1 1 LNCSTSPEIFRK 12 1 Q9BRS8 Q9BRS8 LARP6 La-related protein 6 1 LNCS(0.062)T(0.831)S(0.107)PEIFRK 119.17 0.0037162 0.0 28650.0 21916.0 25131.0 23767.0 20352.0 18029.0 14234.0 16575.0 22068.0 12273.0 True False 28241.445746233458 21865.254848515033 23064.826188465373 25514.904464387786 19154.9353735715 17257.941697651713 14970.966872503099 17345.135010012415 19582.46945365785 14394.371697255458 1.9619783579451537 1.519014188905795 1.6023503264726096 1.7725611788427456 1.330723964646802 1.198936783113795 1.0400569880627426 1.2049942418340893 1.36042544027063 1.0 13.813217197347196 -6.433198661801324 3.1170588112221336 1.1689469262517465 1.6926146181574107 0.7679726592098477 0.143225595229032 0.13082502622661266 2.446881849114274 0.047570086115519016 0.053460273159548356 3.6880885364114433e-07 6.433198661801324 0.5236676919056642 LNDGHFMPVLGFGTYAPAEVPK ddPTM_PC-9_AZD4547_30min_R2 1 LNDGHFMPVLGFGTYAPAEVPK 22 0 B4DK69;P52895;S4R3P0;P52895-2;Q04828 B4DK69;Q04828 AKR1C2;AKR1C1 Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 69.27 0.011588 0.0 14685.0 13200.0 16213.0 25071.0 20484.0 16765.0 18059.0 22378.0 15940.0 19107.0 False True 19354.524533024825 17466.641859931093 15998.005026613993 19291.26829308877 17640.150179577515 15716.681899738887 19666.216015081398 18919.994295282806 16782.555857845033 18438.069745718174 1.0497044864210625 0.9473140139296483 0.8676615962106972 1.0462737455241882 0.9567243438632747 0.8524038642054022 1.066609264760398 1.0261374729682073 0.9102121908255827 1.0 14.170400009609455 -7.295955562496928 24.999684818459546 1.0029178239526366 0.9535553606937691 0.09934072990042808 0.06978418713308085 1575.6042891949453 1141186.3759016844 0.029433297501289563 0.019845212549962864 5.058764212031807e-08 7.295955562496928 -0.049362463258867506 LNDGHFMPVLGFGTYAPAEVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LNDGHFMPVLGFGTYAPAEVPK 22 0 B4DK69;P52895;S4R3P0;P52895-2;Q04828 B4DK69;Q04828 AKR1C2;AKR1C1 Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 ; 106.23 2.4421999999999998e-05 21361000.0 112736.0 114107.0 117958.0 154000.0 153634.0 136338.0 129659.0 119953.0 122978.0 115991.0 False True 131819.97816250453 125434.78885310845 120770.56607820634 145371.8792747361 123530.52057089719 129188.19527066791 117376.76087013091 116804.3608507092 124776.32059848151 137019.25011574902 0.9620544416288053 0.9154537683365335 0.8814131297331115 1.060959530518019 0.9015559526602501 0.9428470463933666 0.8566443092556351 0.8524667939142639 0.9106481059637598 1.0 17.06401906905006 -7.22394244195371 21.002790214503143 0.8926454031855159 0.9432834557967472 0.07982227930166452 0.05941659651247482 169.05172873082668 94688.4170921556 0.022248467259463275 0.01723200052116379 5.971144182868096e-08 7.22394244195371 0.05063805261123133 LNDGHFMPVLGFGTYAPAEVPK ddPTM_PC-9_Lapatinib_30min_R1 2 LNDGHFMPVLGFGTYAPAEVPK 22 0 B4DK69;P52895;S4R3P0;P52895-2;Q04828 B4DK69;Q04828 AKR1C2;AKR1C1 Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 ; 95.344 0.00011227 12688900.0 95846.0 77934.0 95555.0 82223.0 91170.0 77363.0 85724.0 71249.0 74981.0 79473.0 False True 94479.2184639962 77753.54861125068 87698.83675296664 88269.9537078874 85807.55984711637 74054.36483196124 90162.36926924653 74559.48864726248 66535.85019506606 93209.80215888385 1.0136189142741505 0.8341778097405818 0.9408756881972209 0.9470029080999864 0.9205851515578829 0.7944911706359963 0.9673056607883073 0.7999103841049855 0.7138288962533166 1.0 16.508194059562136 -6.6412617905731395 8.622503868478937 0.8497423347026313 0.9280427763994316 0.15694452605013276 0.08779086345664681 0.49392188291959366 35.13329948448271 0.028378262932617044 0.02835515860144661 2.284221470848356e-07 6.6412617905731395 0.07830044169680028 LNDGHFMPVLGFGTYAPPEVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LNDGHFMPVLGFGTYAPPEVPR 22 0 A0A0A0MSS8;P42330 A0A0A0MSS8 AKR1C3 Aldo-keto reductase family 1 member C3 0 ; 107.56 2.0286e-05 11633700.0 53289.0 54341.0 69283.0 84757.0 82320.0 76265.0 70752.0 65737.0 69335.0 59060.0 False True 62309.77519427422 59735.61535284225 70934.96947724078 80008.34007590132 66189.9869390645 72265.52914314062 64049.858359878635 64011.47340410893 70348.89320606718 69767.11048129723 0.8931110198548049 0.8562145535446223 1.0167393917834195 1.1467916547489736 0.9487276523629044 1.035810837579595 0.9180523303605752 0.9175021433812822 1.008338925329664 1.0 16.090259462860114 -5.261344986766689 24.999091245099912 0.9979561953208401 0.8746627791754006 0.3819347022194973 0.06325453616203561 8.89174570547492 2354023.27538218 0.017524921161351608 0.04079444493943241 5.478416078092779e-06 5.261344986766689 -0.12329341614543954 LNDGHFMPVLGFGTYAPPEVPR ddPTM_PC-9_Lapatinib_30min_R1 2 LNDGHFMPVLGFGTYAPPEVPR 22 0 A0A0A0MSS8;P42330 A0A0A0MSS8 AKR1C3 Aldo-keto reductase family 1 member C3 0 ; 101.75 0.00046210000000000006 4614600.0 46762.0 41265.0 55313.0 41015.0 47775.0 51377.0 44685.0 42022.0 45614.0 38398.0 False True 46095.165304899434 41169.453427814056 50765.378654354565 44031.379922029104 44964.9684292639 49179.72547563656 46998.57065461582 43974.49552885315 40476.47098328574 45035.04313788111 1.0235399389709168 0.9141648493989001 1.1272417015107374 0.977713728112147 0.9984439959699235 1.092032382983756 1.0435999919156975 0.9764506141188553 0.8987772224256861 1.0 15.458760422910313 -7.950494394740175 5.275066208795664 0.945437231568823 1.0242106866993619 0.21526060178367246 0.05976264536149785 0.26913857727364754 16.48274586767742 0.03420749932007957 0.015567528541369424 1.1207418909968246e-08 7.950494394740175 0.0787734551305389 LNDS(ph)PTLK ddPTM_PC-9_AZD4547_30min_R2 3 LNDSPTLK 8 0 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 LNDS(0.995)PT(0.005)LK;LNDS(0.996)PT(0.004)LK;LNDS(0.991)PT(0.009)LK 124.6 0.0033629 126308900.0 847125.0 748756.0 952967.0 1117790.0 1056106.0 944600.0 872523.0 977980.0 788448.0 897847.0 True False 1116493.1287053905 990776.7342783762 940330.0349224227 860100.7851833474 909483.9116165243 885534.0126748203 950175.8566989813 826855.6627446894 830123.7516315063 866413.6498133575 1.2886375104384666 1.1435377714695618 1.0853130431693778 0.9927137982747963 1.0497109686723485 1.0220683998521742 1.0966769243578605 0.9543428395002899 0.958114812492083 1.0 19.724696446333787 -1.5228787452804626 0.6064436398563742 1.0042054883069063 20.09009650273073 0.8263527289012534 0.04006659171624554 72.35053900205939 0.5479966934954975 0.01888988220220585 1833.2349314846117 0.02999999999999136 1.5228787452804626 19.085891014423826 LNDS(ph)PTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LNDSPTLK 8 0 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 LNDS(0.893)PT(0.107)LK;LNDS(0.991)PT(0.009)LK;LNDS(0.937)PT(0.063)LK 89.35600000000001 0.010286 57283700.0 375402.0 336525.0 312073.0 398781.0 452615.0 360719.0 366507.0 390954.0 360669.0 302587.0 True False 438950.144072527 369932.97798375424 319514.00386344263 376438.5934354466 363928.3398739629 341802.26063049235 331788.80367910565 380691.87175000267 365943.1018062885 357443.62782262586 1.2280262114236014 1.03494075481834 0.8938864173066052 1.0531411504760315 1.0181419153863192 0.9562410238296507 0.9282269366506909 1.065040308786574 1.0237785019009498 1.0 18.44735620787054 -4.786520514713652 4.018889494095196 0.9925447127572562 1.2474686754897306 0.6555080049763928 0.05097712354206164 0.13616324159432322 4.144141882620395 0.013023060441464637 0.09958162014673924 1.6348559238228327e-05 4.786520514713652 0.2549239627324744 LNDS(ph)PTLK ddPTM_PC-9_Lapatinib_30min_R1 3 LNDSPTLK 8 0 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 LNDS(0.992)PT(0.008)LK;LNDS(0.968)PT(0.032)LK;LNDS(0.982)PT(0.018)LK 94.538 0.0067027 136452800.0 882362.0 798407.0 871711.0 831927.0 867685.0 872312.0 755386.0 754451.0 816543.0 638827.0 True False 869779.3560746246 796558.337645481 800042.2864817684 893109.6868071165 816649.4742343454 835005.2492185908 794496.1909479148 789505.547718787 724575.3287610188 749247.3957665274 1.1608707097136926 1.0631446197160972 1.067794550908348 1.1920090638331935 1.0899597100352434 1.1144586606995512 1.060392328938421 1.0537314539626434 0.9670708671863083 1.0 19.515082638666158 -7.8120385580814045 1.3738683341812095 0.9847704671432632 1.1132401240074594 0.6192193660531533 0.039483022298552516 0.30059094387032803 1.0372844224265902 0.033105784073797814 0.012409169679663415 1.5415635818280966e-08 7.8120385580814045 0.1284696568641962 LNDSPT(ph)LK ddPTM_PC-9_Lapatinib_30min_R1 1 LNDSPTLK 8 0 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 LNDS(0.334)PT(0.666)LK 87.181 0.029141000000000004 7760700.0 101550.0 79708.0 74834.0 79329.0 96310.0 89157.0 67536.0 78963.0 83538.0 79056.0 True False 100101.87837801079 79523.44102324509 68681.43738759363 85163.11929378644 90645.23515274521 85343.96294511812 71032.68362381404 82631.90924860386 74129.07074586148 92720.7242645015 1.0796063034673165 0.8576663055002791 0.74073447907577 0.9184906607377685 0.9776156934901025 0.9204410731484374 0.7660928469581549 0.8911913696109879 0.7994876154590402 1.0 16.500604215185504 LNECIS(ph)PVANEMNHLPAHSHDLQR ddPTM_PC-9_AZD4547_30min_R2 8 LNECISPVANEMNHLPAHSHDLQR 24 0 P23497;P23497-5;P23497-2;P23497-3;P23497-4 P23497 SP100 Nuclear autoantigen Sp-100 1 LNECIS(1)PVANEMNHLPAHSHDLQR;LNECIS(1)PVANEMNHLPAHSHDLQR;LNECIS(0.999)PVANEMNHLPAHS(0.001)HDLQR;LNECIS(1)PVANEMNHLPAHSHDLQR;LNECIS(1)PVANEMNHLPAHSHDLQR;LNECIS(1)PVANEMNHLPAHSHDLQR;LNECIS(0.998)PVANEMNHLPAHS(0.002)HDLQR;LNECIS(1)PVANEMNHLPAHSHDLQR 110.16 2.5919e-07 271318100.0 273860.2 330660.0 398835.0 484138.0 427128.0 405780.0 340963.0 459670.4 330307.0 387478.0 True False 360942.04695397307 437539.37859127397 393546.1873058402 372527.4639575366 367828.6499659526 380406.51245308935 371308.046467147 388638.9018549625 347766.3536848949 373912.5131591235 0.9653114946714002 1.1701651140117721 1.0525087378885374 0.9962957933932598 0.9837291800112028 1.0173676971628982 0.9930345559447268 1.0393845837664493 0.930074125486403 1.0 18.512341226912753 -5.672898767122792 4.44872199391449 0.9963349196687976 1.0770188314939837 0.25522998498191773 0.05305834208269283 0.24708538736613164 8.76678345615367 0.013726552011848471 0.02429749207033764 2.1237394422682793e-06 5.672898767122792 0.08068391182518608 LNECIS(ph)PVANEMNHLPAHSHDLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 LNECISPVANEMNHLPAHSHDLQR 24 0 P23497;P23497-5;P23497-2;P23497-3;P23497-4 P23497 SP100 Nuclear autoantigen Sp-100 1 LNECIS(0.993)PVANEMNHLPAHS(0.007)HDLQR;LNECIS(0.997)PVANEMNHLPAHS(0.003)HDLQR;LNECIS(1)PVANEMNHLPAHSHDLQR;LNECIS(0.984)PVANEMNHLPAHS(0.016)HDLQR;LNECIS(1)PVANEMNHLPAHSHDLQR;LNECIS(0.998)PVANEMNHLPAHS(0.002)HDLQR;LNECIS(1)PVANEMNHLPAHSHDLQR 127.25 1.0727000000000001e-07 249699800.0 188690.6 262933.3 248719.0 250155.0 314705.0 248326.0 272216.0 222552.0 235615.59999999998 190477.1 True False 220632.19177077268 289035.5803583576 254649.40423206025 236139.62636345267 253040.81437874562 235303.3474070611 246429.7298068288 216710.24581333544 239061.0324090776 225009.09041410565 0.9805479030412605 1.2845506811587828 1.131729405969353 1.0494670501038976 1.1245804065651326 1.045750404901464 1.095198995530806 0.963117736330132 1.0624505524159527 1.0 17.779623762236582 -6.931526673089187 0.6971754433291197 1.007944044718498 1.1381104501173651 0.2155627902478655 0.07857616607894825 1.001933679123501 1.0379334821492525 0.05981252612201943 0.05176727190821435 1.170774694575293e-07 6.931526673089187 0.13016640539886715 LNECIS(ph)PVANEMNHLPAHSHDLQR ddPTM_PC-9_Lapatinib_30min_R1 5 LNECISPVANEMNHLPAHSHDLQR 24 0 P23497;P23497-5;P23497-2;P23497-3;P23497-4 P23497 SP100 Nuclear autoantigen Sp-100 1 LNECIS(1)PVANEMNHLPAHSHDLQR;LNECIS(1)PVANEMNHLPAHSHDLQR;LNECIS(1)PVANEMNHLPAHSHDLQR;LNECIS(1)PVANEMNHLPAHSHDLQR;LNECIS(1)PVANEMNHLPAHSHDLQR 95.654 2.3178e-06 119442000.0 140331.8 197675.0 231989.0 181641.0 227012.0 231932.0 232059.0 222412.0 233128.0 200686.0 True False 138330.64279829996 197217.2956826159 212915.7599234372 194999.48507661326 213659.60048276393 222012.80901989894 244073.87954659257 232746.0734749253 206870.66969332725 235374.30770271394 0.5877049375032743 0.8378879479561053 0.9045836905545245 0.8284654641359774 0.9077439358956014 0.9432329772385734 1.0369605838835498 0.9888338100558189 0.8789008100009462 1.0 17.84459732593981 -4.118245862844909 0.709442542762959 0.9588195919383512 3.18935726213824e-31 0.7820502122810907 0.05618022608864836 3.3787745896987498 0.6550327311533551 0.024091303647900544 3.224688822717063 7.616477038606492e-05 4.118245862844909 -0.9588195919383512 LNEQAS(ph)EEILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LNEQASEEILK 11 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;Q01105-2 Q01105;Q01105-2 SET Protein SET 1 LNEQAS(1)EEILK 78.763 0.018029 2145700.0 5891.0 12206.0 9642.6 7848.6 10734.0 8094.2 7009.1 6056.3 5067.9 7214.1 True False 6888.229947446366 13417.731013356251 9872.516153764147 7408.868387504522 8630.749754663731 7669.725902975262 6345.147306510425 5897.328542180274 5142.008449975155 8521.959223215825 0.8082918219886813 1.574488995066204 1.1584796283546026 0.8693855712570202 1.012765906125382 0.8999956115820317 0.7445643824749535 0.6920155785437886 0.6033833670509843 1.0 13.056969433032824 -6.333802711556106 0.9323711480292018 0.7407023876878255 1.21330931070436 0.36006889615265636 0.21104408177231507 0.5598718026382842 1.0453999049624916 0.10383402099837442 0.15287371524665164 4.6365749918481014e-07 6.333802711556106 0.4726069230165345 LNEQAS(ph)EEILK ddPTM_PC-9_Lapatinib_30min_R1 2 LNEQASEEILK 11 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;Q01105-2 Q01105;Q01105-2 SET Protein SET 1 LNEQAS(1)EEILK;LNEQAS(1)EEILK 132.97 8.1716e-05 4279800.0 21514.7 34861.0 31551.0 30365.0 40662.0 36866.0 39014.0 43368.0 36367.0 34745.0 True False 21207.896432687226 34780.28149635346 28956.99857038203 32598.14339467057 38270.34110456782 35289.32711884341 41033.954023031925 45383.03560266774 32270.965498512556 40750.62695519766 0.5204311692186665 0.8534907091022634 0.7105902591932669 0.7999421317004485 0.9391350259872878 0.8659824340283513 1.0069527045104303 1.1136769908488298 0.791913349799308 1.0 15.314534635167925 -4.004004228753936 0.3786557635646834 0.9964937430304561 7.322712800528332e-14 0.5977797001737427 0.10182159723089619 7.535594750357213 0.5442716803454165 0.08336818283063964 3.832727938248379 9.908222971439189e-05 4.004004228753936 -0.9964937430303829 LNEQASEEILK ddPTM_PC-9_Lapatinib_30min_R1 2 LNEQASEEILK 11 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;Q01105-2 Q01105;Q01105-2 SET Protein SET 0 ; 147.91 0.0011029000000000002 12375100.0 47370.0 53455.0 41598.0 52688.0 45517.0 43504.0 50175.0 53027.0 37213.0 50452.0 False True 46694.4951134059 53331.228231765395 38177.97301292358 56562.85128201558 42839.7795498651 41643.43533277718 52772.8159918395 55490.828004580835 33021.68006973761 59172.56097693569 0.7891241200732635 0.901283083768385 0.6451972397781569 0.9558966241813106 0.7239804876209974 0.7037625995097454 0.8918460705530274 0.9377797257450134 0.5580573077208677 1.0 15.852640715549505 -10.756800402438047 4.058762408573068 1.0001516137587663 0.7964861061066523 0.1984900933266479 0.12613368102797304 32209606.632258575 28454738.941818614 39684.7382260844 0.02890118505677671 1.750651086145556e-11 10.756800402438047 -0.203665507652114 LNES(ph)DEQHQENEGTNQLVMGIQK ddPTM_PC-9_AZD4547_30min_R2 1 LNESDEQHQENEGTNQLVMGIQK 23 0 Q15545 Q15545 TAF7 Transcription initiation factor TFIID subunit 7 1 LNES(0.691)DEQHQENEGT(0.309)NQLVMGIQK 53.958 0.011347 6143300.0 39731.0 45467.0 50213.0 45514.0 47985.0 58108.0 49868.0 65304.0 55220.0 53190.0 True False 52364.63154386173 60163.318594355114 49547.14281140867 35021.4504842903 41323.111031391665 54474.49757411432 54306.15539288328 55212.767336631914 58138.8164661357 51327.83428977599 1.0201995129627408 1.1721382642933578 0.9653074885584639 0.6823091402332211 0.805081913218825 1.0613052026815228 1.0580254582005721 1.075688621984773 1.1326956858905772 1.0 15.647453768768973 -6.908687495230825 12.36388806543527 1.0710166827842449 0.9308532652870234 0.23201943454235507 0.12410470487350604 0.97977618228643 127.08855038036215 0.05032385394856859 0.04438432528884447 1.23399245633704e-07 6.908687495230825 -0.1401634174972215 LNES(ph)DEQHQENEGTNQLVMGIQK ddPTM_PC-9_Lapatinib_30min_R1 2 LNESDEQHQENEGTNQLVMGIQK 23 0 Q15545 Q15545 TAF7 Transcription initiation factor TFIID subunit 7 1 LNES(0.816)DEQHQENEGT(0.184)NQLVMGIQK;LNES(0.952)DEQHQENEGT(0.048)NQLVMGIQK 94.588 7.119400000000001e-06 16732400.0 41159.4 72445.0 71231.0 60027.0 84188.0 71592.0 85546.0 80299.0 70322.0 68954.0 True False 40572.45940829045 72277.25805350755 65374.662139611515 64441.58582420189 79236.2273599763 68530.1770491031 89975.15330020734 84029.98468591161 62401.595836511086 80872.60702457055 0.5016835848504774 0.8937174243875733 0.808365954120281 0.7968283476334994 0.9797659587739382 0.8473842945149822 1.1125541343420682 1.0390413735565838 0.7716036137867097 1.0 16.30336349874287 -4.186627728229913 0.6511695127862401 0.960021890826726 2.282845046592747e-24 0.5382080884515993 0.1120050893917489 5.49464814915237 1.0078455640008808 0.049441855720354325 4.669444276024071 6.506872122566961e-05 4.186627728229913 -0.960021890826726 LNFDMTAS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 LNFDMTASPK 10 0 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;A0A087WYS3;Q9ULU4-4;Q9ULU4-18;Q9ULU4-8;Q9ULU4-15;Q9ULU4-17;A0A087WV57 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 LNFDMT(0.033)AS(0.967)PK;LNFDMT(0.006)AS(0.994)PK 131.32 0.00018363 22056400.0 113921.0 116284.0 111476.0 133751.0 119247.0 121937.0 114705.0 127827.0 125841.0 121739.0 True False 150145.50829599777 153870.52894244142 109997.75540287554 102916.77338235058 102691.61240305031 114312.26011383571 124913.52278697127 108074.27432224131 132492.69835050686 117476.95466446801 1.2780847845846541 1.3097933069674728 0.9363347536293037 0.8760592549942794 0.8741426154291548 0.9730611458249736 1.0633023569920008 0.9199614905827089 1.1278186324196613 1.0 16.842018246953657 -5.260090265771939 24.982617009727885 0.9649488384027607 1.2939390778053876 0.7446573045416209 0.0754896396865103 54.841870218827914 1015525.4905873175 0.02023432707387917 0.04788727013671216 5.494266666121351e-06 5.260090265771939 0.32899023940262695 LNFDMTAS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LNFDMTASPK 10 0 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;A0A087WYS3;Q9ULU4-4;Q9ULU4-18;Q9ULU4-8;Q9ULU4-15;Q9ULU4-17;A0A087WV57 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 LNFDMT(0.003)AS(0.997)PK;LNFDMT(0.094)AS(0.906)PK 71.176 0.029810000000000003 29595900.0 159161.0 167703.0 119234.0 178382.0 153805.0 133002.0 188187.0 147833.0 120413.0 124599.0 True False 186103.81372695824 184351.44552948378 122076.99075746287 168387.83486224708 123668.01434843057 126027.1409833604 170360.5650041055 143952.54039201132 122173.81232598466 147187.81237485842 1.2643969002881055 1.2524912392880525 0.8293960538428058 1.1440338173747455 0.8402055330061735 0.8562335355755818 1.1574366264119114 0.9780194302052163 0.8300538635279936 1.0 17.167298690979173 -5.2434245666518 23.850683737561287 0.9600737761368542 1.2584442366582387 0.5243615730177666 0.11572098384833725 353.48745037050014 467995.3195924926 0.02904987063693626 0.07645415174840506 5.709202316677354e-06 5.2434245666518 0.2983704605213845 LNFDMTAS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 LNFDMTASPK 10 0 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;A0A087WYS3;Q9ULU4-4;Q9ULU4-18;Q9ULU4-8;Q9ULU4-15;Q9ULU4-17;A0A087WV57 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 LNFDMT(0.009)AS(0.991)PK;LNFDMTAS(1)PK;LNFDMT(0.042)AS(0.958)PK 120.59 0.00069341 32774800.0 186895.0 217692.0 178703.0 203646.0 203940.0 187240.0 202654.0 187246.0 173186.0 174672.0 True False 184229.84302765466 217187.94754895617 164010.72915352875 218622.80618314145 191944.65016146688 179232.1816777582 213146.43252636233 195946.13273513058 153679.96895057042 204863.82246419013 0.8992795351158585 1.0601576449005303 0.8005841499037614 1.0671616079083772 0.9369377562747493 0.8748844941087034 1.0404298326690649 0.9564701584604166 0.7501566997141891 1.0 17.644305711300817 LNFSHGTHEYHAETIK ddPTM_PC-9_AZD4547_30min_R2 2 LNFSHGTHEYHAETIK 16 0 P14618;P14618-2;H3BTN5;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ; 68.97800000000001 0.006292100000000001 20572000.0 34153.0 30571.0 83519.0 143644.0 108890.0 94379.0 58496.0 115317.0 59094.0 90734.0 False True 45012.943573469354 40452.47790151162 82411.48348965484 110529.09507767693 93772.50307821698 88477.46621028674 63702.030678232535 97497.40737103992 62217.58819720796 87557.4302772802 0.5140962158313767 0.4620107942113556 0.9412277544997725 1.262361112331063 1.0709828141512907 1.0105077996246914 0.7275456860314256 1.1135252263832027 0.7105917567495407 1.0 16.41794199303785 -5.287363377236156 5.799182677578252 0.9908858359099304 0.4855664440183265 0.6107399924108263 0.1569613159136824 0.10453193355115487 12.059734255963832 0.04188365945301739 0.09413498307302944 5.159844607929395e-06 5.287363377236156 -0.5053193918916039 LNFSHGTHEYHAETIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LNFSHGTHEYHAETIK 16 0 P14618;P14618-2;H3BTN5;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 54.768 0.019269 3360800.0 15333.0 12308.0 23415.0 28620.0 31389.0 32284.0 25550.0 20294.0 23657.0 21572.0 False True 17928.57405944579 13529.856899261738 23973.30240188201 27016.51418729193 25238.550777821856 30590.970207266128 23129.719034018843 19761.304003270383 24002.938870353046 25482.832836141963 0.7035549844371278 0.5309400640917961 0.9407628483078614 1.0601848845068265 0.9904138578355526 1.2004540627005709 0.9076588612712739 0.7754751651960448 0.9419258457132755 1.0 14.637238045349358 -5.3199637949378715 6.228177171527608 0.9796057597040878 0.6180030328196741 0.6336629421709717 0.10955383871441533 0.13332201863782767 11.029194785970471 0.031171577204191215 0.06666554665338542 4.78669995096637e-06 5.3199637949378715 -0.36160272688441375 LNFSHGTHEYHAETIK ddPTM_PC-9_Lapatinib_30min_R1 1 LNFSHGTHEYHAETIK 16 0 P14618;P14618-2;H3BTN5;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 55.782 0.018119 3163900.0 26353.0 20294.0 29782.0 23511.0 26427.0 25851.0 27092.0 24780.0 33868.0 23238.0 False True 25977.201387451674 20247.01048985964 27333.438921844554 25240.077370396833 24872.61581748103 24745.412991624282 28494.691197825912 25931.369263837554 30053.42919414918 27254.657337311346 0.953128893383266 0.7428825921117596 1.0028905732902156 0.926083093176278 0.9126005698640971 0.9079333739319505 1.045498053604841 0.9514472679991385 1.1026896732620572 1.0 14.734215161487496 -7.224037352272869 0.9467516963007103 1.0378067756686356 0.8942576297288812 0.35794789431442875 0.07351616430905845 0.6274786330648952 1.103336556425404 0.05313290594721029 0.03149217516307786 5.969839397054147e-08 7.224037352272869 -0.14354914593975432 LNGLENR ddPTM_PC-9_Lapatinib_30min_R1 1 LNGLENR 7 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 108.09 0.045207 2629700.0 19404.0 22584.0 28540.0 24037.0 25094.0 22681.0 24021.0 20512.0 27610.0 21762.0 False True 19127.295401742205 22531.708135556815 26193.551367585922 25804.7611650814 23618.0202567022 21710.986501993353 25264.689844344328 21465.06240273753 24500.27105381065 25523.53270395772 0.7493984325600936 0.8827817213587762 1.0262510159310474 1.0110183987610804 0.9253429190481908 0.8506262339862856 0.989858658571458 0.8409910435090016 0.9599090900928303 1.0 14.639540405429429 -4.848695365142642 3.531567639741424 0.9444779117136224 0.7395995746875652 0.5023579903215255 0.0606386958430905 0.22180010589555194 4.620152820603132 0.01582154085957648 0.10812981437224528 1.4167872336084622e-05 4.848695365142642 -0.20487833702605718 LNGPGENVS(ph)EDEAQSSNQR ddPTM_PC-9_AZD4547_30min_R2 4 LNGPGENVSEDEAQSSNQR 19 0 A0A3B3ISF0;Q659C4;H0Y9K3;D6R9W6;Q659C4-9;Q659C4-2;G3V0E9;A0A3B3IT29;A0A3B3ISF8;D6RJB0;Q659C4-3 A0A3B3ISF0 LARP1B La-related protein 1B 1 LNGPGENVS(0.99)EDEAQS(0.009)SNQR;LNGPGENVS(0.976)EDEAQS(0.024)SNQR;LNGPGENVS(1)EDEAQSSNQR;LNGPGENVS(1)EDEAQSSNQR 267.69 1.5537999999999997e-78 47443800.0 53288.0 55293.2 70497.0 95401.0 81413.0 74931.0 65120.0 80190.0 52667.0 68725.0 True False 70232.47554074424 73165.64558254098 69562.16371807842 73407.77338075712 70110.2102406728 70245.55272468446 70915.55384584417 67798.47808288196 55450.870098188476 66318.95866826196 1.0590105295841319 1.1032387578418903 1.0489031359198429 1.1068897168297613 1.0571669345921924 1.0592077157915576 1.0693104244982965 1.0223091472533639 0.8361239562816811 1.0 16.017133733549443 -8.052848765943343 5.324054576412793 0.9182666959141155 1.0711603138523886 0.6873828260778219 0.04100006365031432 0.10541822423736814 6.5569140007566045 0.025758536537965317 0.00968611278768457 8.854238866786651e-09 8.052848765943343 0.15289361793827316 LNGPGENVS(ph)EDEAQSSNQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LNGPGENVSEDEAQSSNQR 19 0 A0A3B3ISF0;Q659C4;H0Y9K3;D6R9W6;Q659C4-9;Q659C4-2;G3V0E9;A0A3B3IT29;A0A3B3ISF8;D6RJB0;Q659C4-3 A0A3B3ISF0 LARP1B La-related protein 1B 1 LNGPGENVS(1)EDEAQSSNQR;LNGPGENVS(1)EDEAQSSNQR;LNGPGENVS(1)EDEAQSSNQR;LNGPGENVS(0.999)EDEAQSSNQR 288.69 2.8659999999999995e-106 34284900.0 70504.0 81218.0 79959.0 88271.0 97227.0 91608.0 96127.0 92899.0 96439.0 71697.0 True False 82438.93468252571 89280.78628893736 81865.52580619605 83325.46204844335 78176.06729985953 86803.91521333266 87021.15466078764 90460.49968462661 97849.23793033673 84695.0985468601 0.9733613408208492 1.0541434843427226 0.9665910685599061 0.9838286214678769 0.9230294154106955 1.024898922164968 1.0274638810726524 1.0680724296527813 1.1553116958261607 1.0 16.369990860243306 -7.490277670864721 1.9037041765207225 1.0842494095702937 0.9853041237461825 0.4043126503338035 0.04754659341542579 0.3306829235190031 2.3519143544675027 0.028136792636703073 0.014618109472350758 3.23386829957818e-08 7.490277670864721 -0.09894528582411122 LNGPGENVS(ph)EDEAQSSNQR ddPTM_PC-9_Lapatinib_30min_R1 4 LNGPGENVSEDEAQSSNQR 19 0 A0A3B3ISF0;Q659C4;H0Y9K3;D6R9W6;Q659C4-9;Q659C4-2;G3V0E9;A0A3B3IT29;A0A3B3ISF8;D6RJB0;Q659C4-3 A0A3B3ISF0 LARP1B La-related protein 1B 1 LNGPGENVS(1)EDEAQSSNQR;LNGPGENVS(1)EDEAQSSNQR;LNGPGENVS(1)EDEAQSSNQR;LNGPGENVS(0.999)EDEAQS(0.001)SNQR 282.97 7.412099999999999e-106 53360500.0 92274.0 87453.0 94789.0 93300.0 92741.0 83740.0 70502.0 77610.0 94626.0 67811.0 True False 90958.1558390209 87250.50795159646 86995.81431612108 100161.59323967592 87286.1567158213 80158.63540747418 74152.24859106466 81216.0439292345 83968.22342404522 79532.04099752208 1.1436668127485223 1.0970485210396506 1.0938461181806152 1.2593866821900945 1.0974967525168984 1.0078785154020078 0.9323569175519457 1.0211738930698997 1.0557785563011184 1.0 16.2792485742306 -6.671227560129728 3.9868394041690878 0.9998609770618089 1.1444997448852483 0.6395621526068269 0.05151742876819148 0.1508781899356586 4.522304906347184 0.018528293408861498 0.018232977491353997 2.1319275403695248e-07 6.671227560129728 0.14463876782343943 LNGTDPEDVIR ddPTM_PC-9_AZD4547_30min_R2 1 LNGTDPEDVIR 11 0 J3QRS3;P19105;O14950;J3KTJ1;P24844 J3QRS3 MYL12A;MYL12B;MYL9 Myosin regulatory light chain 12A;Myosin regulatory light chain 12B;Myosin regulatory light polypeptide 9 0 112.94 0.0074895 3021400.0 9723.0 8767.4 13282.0 15126.0 17425.0 15641.0 12554.0 15779.0 13785.0 12561.0 False True 12814.711749036469 11601.290594148471 13105.872001695372 11638.934394370408 15005.839527393982 14662.965797424144 13671.281679679481 13340.718115348445 14513.646957364732 12121.243213270845 1.0572110074490038 0.957104018954664 1.0812316666780941 0.9602096245068009 1.237978585477516 1.2096915753138682 1.1278778454599103 1.1006064213563893 1.1973728026077872 1.0 13.565250055723224 -6.253629274651672 24.999408431110854 1.1529378774853265 1.0146860445898849 0.4438814088556612 0.07190550829332641 528.3729542110756 1691270.1635448618 0.020630466355534716 0.026129152547088013 5.576615806045619e-07 6.253629274651672 -0.13825183289544163 LNGTDPEDVIR ddPTM_PC-9_Lapatinib_30min_R1 2 LNGTDPEDVIR 11 0 J3QRS3;P19105;O14950;J3KTJ1;P24844 J3QRS3 MYL12A;MYL12B;MYL9 Myosin regulatory light chain 12A;Myosin regulatory light chain 12B;Myosin regulatory light polypeptide 9 0 ; 123.62 0.0025472 18531100.0 45471.0 47476.0 49676.0 46659.0 46576.0 46462.0 48921.0 42773.0 48015.0 43384.0 False True 44822.57520163988 47366.07223891676 45591.8310349053 50090.45850986115 43836.49125193918 44474.92856821199 51453.890007708585 44760.38973051348 42607.04507963483 50882.8665944537 0.8808972096419897 0.9308845080689641 0.8960153797599696 0.9844268191313159 0.8615177207157865 0.8740649170316166 1.0112223121744703 0.8796750797721845 0.837355438702407 1.0 15.634892329753201 -12.036231002799594 2.3453308917849953 2.4556723267080014 0.908999556580181 0.22484915066368438 0.052003658767594683 4060006.786558295 819731.3576426714 32083137.863733344 0.01283841695009938 9.19960111494151e-13 12.036231002799594 -1.5466727701278205 LNHQEFK ddPTM_PC-9_AZD4547_30min_R2 1 LNHQEFK 7 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 84.568 0.010341 0.0 31408.0 29233.0 32950.0 40973.0 45223.0 34764.0 29067.0 41217.0 32289.0 41186.0 False True 41395.090673016275 38681.99556752774 32513.061470852463 31527.30787653964 38944.567055801315 32590.20158440337 31653.906689759737 34847.85972243598 33995.73062070002 39744.09067604276 1.0415407666621674 0.9732766534483769 0.8180602680249753 0.793257748265553 0.9798832076255455 0.8200011883539793 0.7964430976109944 0.8768060642394274 0.8553656667553907 1.0 15.278452749729338 -5.0704282555944005 3.9632374365909047 0.8606170321409577 1.0308511492887291 0.4146680028870945 0.06814743497286192 0.18887489223703985 5.601866641477169 0.01709025890954297 0.057357997855604005 8.502991489633426e-06 5.0704282555944005 0.17023411714777137 LNHQEFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LNHQEFK 7 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 86.95299999999999 0.0080043 0.0 31058.0 28898.0 30557.0 39824.0 42932.0 34025.0 38628.0 32472.0 35885.0 32181.0 False True 36315.505976538654 31766.802459771352 31285.594768067822 37592.79039115 34519.78278994069 32240.66910241077 34968.87619749822 31619.644406927975 36409.750237249835 38015.16055534417 0.9552900854823149 0.8356350991474525 0.8229767890239699 0.9888894283747859 0.908053057928961 0.8481003008121816 0.9198665923451504 0.8317640632056436 0.9577692085304466 1.0 15.214287263792842 -8.489310608799553 6.473972583011285 0.9999375248359245 0.8886626592882279 0.3322916676266653 0.0527752176745112 0.1886907935880143 24.963956856822385 0.05042838315471756 0.013058341800384725 3.2410773155247322e-09 8.489310608799553 -0.11127486554769661 LNHS(ph)PPQSSSR ddPTM_PC-9_AZD4547_30min_R2 1 LNHSPPQSSSR 11 0 A0A087X0H9;Q5T8P6-3;Q5T8P6-2;Q5T8P6 A0A087X0H9 RBM26 RNA-binding protein 26 1 LNHS(0.999)PPQSSSR 58.626000000000005 0.040395 26916000.0 3326.5 4064.7 5114.9 6071.1 7735.5 4832.6 4509.2 6255.4 3705.3 4646.1 True False 4384.2578045016735 5378.534785459239 5047.073083983709 4671.501692559978 6661.5593494494215 4530.416758048205 4910.510064522123 5288.771664791852 3901.1545934801256 4483.441453162781 0.97787778658487 1.199644255790388 1.12571406066278 1.0419455102429258 1.485813837214294 1.0104775104963815 1.0952546421807454 1.1796232247130076 0.8701250220917038 1.0 12.13039084314795 -8.256585006184011 24.96715843342158 0.9350625034528226 1.1435967468286907 0.2619127499561986 0.13717097453776922 481.88783173741126 2478493.8144758577 0.09687677194136599 0.03399451415585326 5.5387912036755055e-09 8.256585006184011 0.20853424337586812 LNHS(ph)PPQSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LNHSPPQSSSR 11 0 A0A087X0H9;Q5T8P6-3;Q5T8P6-2;Q5T8P6 A0A087X0H9 RBM26 RNA-binding protein 26 1 LNHS(1)PPQSSSR;LNHS(0.999)PPQSSSR 80.916 0.008861399999999998 37884100.0 14880.9 15454.0 19646.2 16577.5 22708.4 16052.6 16331.7 16019.1 16651.6 12334.7 True False 17399.9424588278 16988.170988072063 20114.639916628395 15648.716419980145 18258.852033613366 15210.773397012752 14784.643144731324 15598.61559863944 16895.098148267774 14570.883468568521 1.1941583704489824 1.1658984868500235 1.3804681068254063 1.0739716952466651 1.2531053503379064 1.0439156575388557 1.0146703305001314 1.070533274958096 1.1595108961452416 1.0 13.830800733759114 -6.7672122682203435 24.99771424953889 1.0594433564752042 1.212396911300874 0.47339340839911226 0.08214447862623026 129.2558635029128 559699.3646485589 0.028037572395424922 0.025382554085438408 1.7091797225816924e-07 6.7672122682203435 0.15295355482566975 LNHS(ph)PPQSSSR ddPTM_PC-9_Lapatinib_30min_R1 1 LNHSPPQSSSR 11 0 A0A087X0H9;Q5T8P6-3;Q5T8P6-2;Q5T8P6 A0A087X0H9 RBM26 RNA-binding protein 26 1 LNHS(0.999)PPQSSSR 72.815 0.014901 25056000.0 4966.7 4156.8 6282.4 4949.5 5819.4 4722.9 7589.1 6375.4 7009.8 4072.1 True False 4895.873947218769 4147.175184993031 5765.885322765299 5313.502741047985 5477.114333380604 4520.9125766176285 7982.026464248513 6671.624358541967 6220.28250753357 4775.957059267819 1.0251084518689817 0.8683443200029138 1.2072732755367865 1.1125524528611601 1.1468097944373636 0.9465982462812824 1.671293599417789 1.3969188323407506 1.302415920064234 1.0 12.221574150021114 -7.238376862504835 24.998288647280912 1.3757337161455998 1.0570472411881486 0.38622386251839114 0.17801397007680864 746.7496822392359 809429.839450843 0.06649952965057229 0.05147925616401186 5.7759461753540785e-08 7.238376862504835 -0.31868647495745117 LNHVAAGLVS(ph)PSLK ddPTM_PC-9_AZD4547_30min_R2 2 LNHVAAGLVSPSLK 14 0 Q5T757;Q05519-2;Q05519;Q5T760 Q5T757 SRSF11 Serine/arginine-rich splicing factor 11 1 LNHVAAGLVS(0.996)PS(0.004)LK;LNHVAAGLVS(0.937)PS(0.063)LK 179.81 5.4583e-05 209360000.0 356166.0 362312.0 405495.0 508120.0 456625.0 445920.0 406069.0 453459.0 363379.0 422829.0 True False 469419.3792869806 479422.2686026779 400117.8713542736 390980.78437574324 393230.5006712346 418036.55190763855 442208.3543401128 383387.33100119064 382586.4720870681 408025.885409131 1.150464703523135 1.1749800337347645 0.9806188422410309 0.9582254419562217 0.9637391026722216 1.0245343907249163 1.0837752460158423 0.9396152173452548 0.937652452376754 1.0 18.638301154983516 -5.262613025536606 24.995515174499378 0.9869418348198606 1.162722381765125 0.7423891596969031 0.041633109678732294 50.87998897468041 1083633.9695789851 0.011759412857538136 0.026932194292387752 5.462443707838353e-06 5.262613025536606 0.17578054694526446 LNHVAAGLVS(ph)PSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LNHVAAGLVSPSLK 14 0 Q5T757;Q05519-2;Q05519;Q5T760 Q5T757 SRSF11 Serine/arginine-rich splicing factor 11 1 LNHVAAGLVS(0.978)PS(0.022)LK;LNHVAAGLVS(0.861)PS(0.139)LK 99.711 0.0021378 147572000.0 212926.0 217876.0 245864.0 298144.0 326180.0 292879.0 302357.0 290160.0 252871.0 233713.0 True False 248970.16631980328 239505.2893876792 251726.330204412 281439.9582758891 262267.3705027214 277519.90965598717 273715.5560848862 282543.60744993296 256568.75999006853 276083.3168289097 0.9017935932510237 0.867510909889937 0.9117766806619763 1.019402264173387 0.9499573299651782 1.0052034756883472 0.9914237456604783 1.0233997863225714 0.9293164213506808 1.0 18.074744185776787 -5.624362437070352 5.064840149458707 0.988325304410737 0.8857557478829746 0.6996009548847231 0.028736164069295057 0.1019595291356923 4.17291636833433 0.007428009363237765 0.013166690122695822 2.3748575405717994e-06 5.624362437070352 -0.10256955652776234 LNHVAAGLVS(ph)PSLK ddPTM_PC-9_Lapatinib_30min_R1 2 LNHVAAGLVSPSLK 14 0 Q5T757;Q05519-2;Q05519;Q5T760 Q5T757 SRSF11 Serine/arginine-rich splicing factor 11 1 LNHVAAGLVS(0.571)PS(0.429)LK;LNHVAAGLVS(0.676)PS(0.324)LK 177.66 8.4801e-05 153692000.0 216909.0 272302.0 269175.0 269549.0 299010.0 336810.0 328810.0 315723.0 325250.0 273919.0 True False 213815.8378837614 271671.50144918496 247044.47054554746 289372.53264910483 281422.81967627833 322405.4214424582 345834.172920314 330392.6431834774 288616.9199656612 321265.5341758753 0.6655424100573107 0.8456291526761152 0.7689728410465099 0.9007269746237055 0.8759819829356944 1.003548115640562 1.0764745549424195 1.0284098604944205 0.898374986616707 1.0 18.293406689168755 -5.959995659284499 0.8483737310451502 1.0095006377744455 0.7231139858935169 0.7315238466717381 0.062096392744169726 0.3831654994694346 0.5457047336064572 0.029709490334021767 0.07393372233013978 1.0964891553514782e-06 5.959995659284499 -0.2863866518809286 LNHVAAGLVS(ph)PSLKSDTSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LNHVAAGLVSPSLKSDTSSK 20 1 Q5T757;Q05519-2;Q05519;Q5T760 Q5T757 SRSF11 Serine/arginine-rich splicing factor 11 1 LNHVAAGLVS(0.927)PS(0.058)LKS(0.008)DT(0.002)S(0.002)S(0.003)K 61.096000000000004 0.0052341 6196900.0 27627.0 5774.4 13377.0 43215.0 45422.0 90508.0 47600.0 82505.0 81951.0 44176.0 True False 32303.705441877555 6347.644270319871 13695.958412555 40793.80365492037 36521.88516455527 85761.6011497721 43090.983405843304 80339.33117127333 83149.37833893999 52184.75910297638 0.6190256695088413 0.12163789542065416 0.26245131045883946 0.7817187308352196 0.6998573106850317 1.6434223827792023 0.825738858366898 1.5395171416378377 1.5933651849357207 1.0 15.671340899426866 -6.340473162947164 1.4224852892034288 1.3299349640004012 0.3229313486792371 0.6546646093042849 0.2997883884505806 0.2391186662504464 0.9761296298206537 0.11374296976538344 0.14762252360413067 4.5659046415458407e-07 6.340473162947164 -1.0070036153211641 LNLEAINYMAADGDFK ddPTM_PC-9_Lapatinib_30min_R1 1 LNLEAINYMAADGDFK 16 0 P09382 P09382 LGALS1 Galectin-1 0 116.84 0.00070335 811610.0 3163.0 2993.7 4818.2 4024.0 3730.4 3930.1 3113.7 3043.9 3494.2 2867.4 False True 3117.895039976841 2986.76827158238 4422.066194789852 4319.9383836704865 3510.9852062485825 3762.0187845105647 3274.9121505488897 3185.3307063032753 3100.6464004427794 3363.026269429664 0.9271099272458568 0.8881192212896114 1.3149068251375242 1.2845389948152577 1.0439957719521504 1.1186409153885575 0.9737991583111489 0.947162005619265 0.9219810230529714 1.0 11.715544332818252 -7.321767981896025 4.531798747826429 0.9530678321928254 1.103099371272743 0.2125837350162001 0.12732193814390208 0.38022443340880335 16.094946906219434 0.06096989824579383 0.04079734395087479 4.766855839780429e-08 7.321767981896025 0.15003153907991762 LNLGTDSDS(ph)SPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LNLGTDSDSSPQK 13 0 Q16512;Q16512-2;Q16512-3;K7EN76 Q16512 PKN1 Serine/threonine-protein kinase N1 1 LNLGT(0.033)DS(0.136)DS(0.564)S(0.267)PQK;LNLGTDSDS(0.5)S(0.5)PQK;LNLGT(0.009)DS(0.172)DS(0.55)S(0.27)PQK 127.78 0.00011298 38503000.0 173725.0 178640.0 176646.0 207063.0 210709.0 194958.0 203062.0 217968.0 182712.0 153108.0 True False 203133.21127484657 196374.1986093696 180857.91057368522 195461.93141730336 169422.0840372126 184734.05927605578 183826.49731843217 212246.5709561864 185383.81734285594 180865.26839773892 1.1231189552000578 1.0857485262318312 0.9999593187563379 1.0807046214503997 0.9367308911108254 1.0213904577290596 1.0163725680830067 1.1735065158526576 1.0249829554626282 1.0 17.464555867906874 -5.035611472977158 4.662600516065508 1.0354100528553105 1.1167054274691997 0.20820159173782105 0.05841083972521278 0.30236354001298316 15.85303721613602 0.015423286011447046 0.0508607328362557 9.212733896016213e-06 5.035611472977158 0.08129537461388914 LNLGTDSDS(ph)SPQK ddPTM_PC-9_Lapatinib_30min_R1 1 LNLGTDSDSSPQK 13 0 Q16512;Q16512-2;Q16512-3;K7EN76 Q16512 PKN1 Serine/threonine-protein kinase N1 1 LNLGTDSDS(0.661)S(0.338)PQK 98.337 0.0027844000000000002 52986000.0 242740.0 183630.0 223450.0 182170.0 202290.0 191150.0 171030.0 146960.0 199790.0 141080.0 True False 239278.48308693533 183204.81601719314 205078.8035419438 195567.38950130556 190391.69991744182 182974.96009241368 179885.09654378303 153788.29810385642 177287.5463180306 165465.49002271643 1.446092977176602 1.1072086148721483 1.2394052893675227 1.1819225233881487 1.150642952142488 1.1058194676563275 1.0871457034278686 0.9294282335412848 1.071447262469601 1.0 17.336170830051607 -1.5228787453190769 0.2280696843860529 0.9735399620930585 3.083754588343702 0.6822969952552542 0.07529926782464322 29.93932719779316 0.3901916482263848 0.10974545417864798 23.52043188727749 0.029999999997323983 1.5228787453190769 2.1102146262506434 LNLGTDSDSS(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 4 LNLGTDSDSSPQK 13 0 Q16512;Q16512-2;Q16512-3;K7EN76 Q16512 PKN1 Serine/threonine-protein kinase N1 1 LNLGT(0.002)DS(0.038)DS(0.075)S(0.885)PQK;LNLGT(0.003)DS(0.017)DS(0.419)S(0.562)PQK;LNLGTDS(0.059)DS(0.059)S(0.881)PQK;LNLGTDS(0.076)DS(0.076)S(0.849)PQK 211.13 2.0231e-10 263889500.0 314483.0 268718.0 329560.0 411398.0 392767.0 345532.0 306318.0 355153.0 288273.0 330055.0 True False 414482.05234724254 355575.8384331035 325189.8190693212 316556.5471357397 338238.0817019189 323925.82941727334 333579.70858340384 300272.2644540438 303510.52225900657 318499.8749109226 1.3013570333839661 1.116408094453884 1.0210045424987046 0.9938984975246021 1.0619724161477824 1.0170359706039704 1.0473464351491464 0.9427704313479663 0.9529376497993658 1.0 18.28093328030794 -4.6452596184082875 1.4328800226028384 1.0031418449922045 1.5022115076461948 0.8753304547098404 0.034600577941739624 0.5819867599169524 0.8631990572518589 0.0108384297874844 0.45807816670010143 2.263290922561407e-05 4.6452596184082875 0.49906966265399033 LNLGTDSDSS(ph)PQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LNLGTDSDSSPQK 13 0 Q16512;Q16512-2;Q16512-3;K7EN76 Q16512 PKN1 Serine/threonine-protein kinase N1 1 LNLGTDS(0.021)DS(0.284)S(0.695)PQK;LNLGTDSDS(0.011)S(0.989)PQK;LNLGTDSDS(0.222)S(0.778)PQK;LNLGTDS(0.001)DS(0.048)S(0.951)PQK 233.28 8.7695e-26 139608000.0 488036.0 427279.0 469714.0 533643.0 568428.0 500138.0 552276.0 523968.0 459124.0 370939.0 True False 570650.855649624 469696.4353314641 480913.7631602649 503744.7128039497 457048.61389454035 473909.8828373705 499960.4191480154 510214.39518998563 465837.8199227271 438187.3043484906 1.302298925565824 1.071907904839512 1.0975072951401483 1.1496104697805696 1.043043943443531 1.0815235360184459 1.1409742230924989 1.164375120243584 1.0631020463163534 1.0 18.741188159999986 -1.5228787452843515 0.01406956848022635 1.4020938768620692e-10 2.4343820288411933 0.31894891152354465 0.06583670961578747 9359.626289282085 10.208172285783908 716.2972359513094 1085.3538392060152 0.029999999999722724 1.5228787452843515 2.434382028700984 LNLGTDSDSS(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 5 LNLGTDSDSSPQK 13 0 Q16512;Q16512-2;Q16512-3;K7EN76 Q16512 PKN1 Serine/threonine-protein kinase N1 1 LNLGTDS(0.005)DS(0.026)S(0.969)PQK;LNLGT(0.002)DS(0.062)DS(0.14)S(0.796)PQK;LNLGTDS(0.001)DS(0.023)S(0.976)PQK;LNLGTDSDS(0.024)S(0.976)PQK;LNLGTDS(0.015)DS(0.416)S(0.568)PQK 233.28 8.7626e-26 315918500.0 920607.0 688322.0 730442.0 708265.0 758755.0 690430.0 625350.0 591886.0 714402.0 503093.0 True False 907478.9753613529 686728.2326993778 670387.8783476604 760353.1708027789 714126.5226697255 660901.9183709396 657727.5631389503 619387.1843460759 633938.523773431 590051.9547207158 1.5379645268540498 1.1638436703839428 1.1361505931540712 1.2886207133449297 1.2102773610973576 1.12007411056499 1.1146943211979814 1.0497163502140165 1.0743774657495841 1.0 19.170482465382314 -1.5228787452803376 0.3122301282656639 1.0521669100793012 4.434768390065718 0.6721794422194732 0.08303762492590279 38.24361784256674 0.5460788711768244 0.08473325688727028 73.24841693980366 0.029999999999999995 1.5228787452803376 3.382601479986417 LNLTS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 LNLTSPK 7 0 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;A0A0A0MQZ8;H0Y7Y3 Q8IWZ3-6 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 1 LNLT(0.077)S(0.923)PK 94.40899999999999 0.013456999999999998 103820000.0 187660.0 159670.0 184360.0 214790.0 185640.0 202170.0 226650.0 190590.0 159910.0 181150.0 True False 247331.9764295154 211280.20498296953 181915.265941316 165273.48397241952 159867.09037965126 189528.27794036432 246821.4109207703 161138.6948225025 168362.51613726464 174807.99363776887 1.4148779542772412 1.2086415534336326 1.0406575932578608 0.9454572444489785 0.9145296336443421 1.08420830189893 1.4119572325292238 0.921803925948653 0.9631282450740764 1.0 17.41541163248978 -4.9235902018612725 2.3001689970265806 1.0400776075558973 1.450137924371118 0.43287772844712546 0.13678471168684667 0.45560379315808075 3.667893315703495 0.03928221533046809 0.339097662394301 1.1923665886225567e-05 4.9235902018612725 0.4100603168152208 LNLTS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LNLTSPK 7 0 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;A0A0A0MQZ8;H0Y7Y3 Q8IWZ3-6 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 1 LNLT(0.077)S(0.923)PK 94.40899999999999 0.013456999999999998 32815000.0 192050.0 214890.0 171930.0 233500.0 232040.0 203230.0 250030.0 208570.0 197370.0 172320.0 True False 224560.27183959863 236222.85904146504 176029.4632481557 220417.7520172144 186573.42771307754 192572.26103403195 226345.34833955875 203095.2584981819 200256.1628626441 203560.25191563045 1.1031636565898535 1.1604567041868874 0.8647536127097866 1.0828133191177758 0.9165513697163559 0.9460209408359709 1.1119329348903146 0.9977156963941994 0.983768495951971 1.0 17.635096356270367 -5.231247380913662 24.994310317952806 0.9916322468927803 1.1318102235958425 0.4053956379342347 0.0695787961059205 680.6621054508879 563480.962393376 0.017177406609576045 0.04543326436815588 5.871548047182117e-06 5.231247380913662 0.1401779767030622 LNLTS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 LNLTSPK 7 0 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;A0A0A0MQZ8;H0Y7Y3 Q8IWZ3-6 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 1 LNLT(0.08)S(0.92)PK;LNLT(0.066)S(0.934)PK 74.165 0.034581 113079000.0 619450.0 503080.0 438400.0 479360.0 472470.0 401730.0 396370.0 394280.0 396100.0 377700.0 True False 610616.529406782 501915.14916914306 402356.44427293923 514613.73349808226 444680.2435117591 384548.9443783693 416892.09914669476 412599.68818990665 351487.0468820865 442984.9417463852 1.378413737946804 1.133029820811598 0.9082846985424026 1.1616957711233118 1.0038269963730382 0.8680858154283012 0.9410976759236459 0.9314079313019301 0.7934514557005361 1.0 18.75689813295289 -1.5228787452881631 0.5492065155629561 0.9177385755554075 20.697497020643702 0.6926829425030576 0.08977935216529244 78.1645919462929 0.7177617274286313 0.04562106962903395 1823.2292348354379 0.029999999999459428 1.5228787452881631 19.779758445088294 LNMY(ph)RQK ddPTM_PC-9_AZD4547_30min_R2 2 LNMYRQK 7 1 Q13823 Q13823 GNL2 Nucleolar GTP-binding protein 2 1 LNMY(1)RQK;LNMY(1)RQK 89.67299999999999 0.015031000000000001 6022400.0 43331.0 41240.0 65651.0 105537.0 88450.0 70791.0 50171.0 89806.0 56395.0 48087.0 True False 57109.35665921003 54570.023507845355 64780.42484439871 81207.07518039602 76170.24425813471 66364.42757914808 54636.12180589447 75928.54623657932 59375.92456732566 46403.48876654368 1.2307125644480668 1.1759896714315505 1.396024880161695 1.7500209001299332 1.6414766708888595 1.4301603035286428 1.1774140966160804 1.6362680534340086 1.279557338157189 1.0 15.501945655526853 -8.534571533785417 22.69715763969105 0.9999999899991441 1.4312848042375077 0.32601316311060513 0.18944422483580772 643.2535506269377 1248636.9071960063 0.19829106243950761 0.0511985321736284 2.9203067091981645e-09 8.534571533785417 0.4312848142383636 LNMY(ph)RQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LNMYRQK 7 1 Q13823 Q13823 GNL2 Nucleolar GTP-binding protein 2 1 LNMY(1)RQK 86.113 0.006654300000000001 0.0 21563.0 23308.0 20064.0 22162.0 34290.0 22316.0 19573.0 22148.0 17110.0 18132.0 True False 25213.190011336963 25621.864202794335 20542.40185314374 20920.33499017344 27571.120652824622 21145.709674927224 17718.903743751493 21566.638467745754 17360.201381060175 21419.18806716699 1.1771309879848209 1.1962108051177502 0.9590653851456089 0.9767099912737481 1.2872159563829497 0.9872320840835711 0.82724441693065 1.0068840331443183 0.8104976400889468 1.0 14.386616172724784 -6.99172978821078 24.986189732488192 0.9110884699930388 1.1097717022116245 0.4513725638928682 0.10869390899833388 184.62245402789037 557783.3440695971 0.03870659153046718 0.034080079208147346 1.019225338183443e-07 6.99172978821078 0.19868323221858564 LNNSSPNSS(ph)GGVK ddPTM_PC-9_Lapatinib_30min_R1 1 LNNSSPNSSGGVK 13 0 O00472;H0Y8G1;O00472-2 O00472 ELL2 RNA polymerase II elongation factor ELL2 1 LNNS(0.336)S(0.131)PNS(0.161)S(0.372)GGVK 87.184 0.030737 0.0 16605.0 23207.0 14590.0 14760.0 19164.0 15574.0 12859.0 16169.0 16749.0 15177.0 True False 16368.209655015951 23153.26561733383 13390.466519028674 15845.499637916593 18036.81119787364 14907.936324767195 13524.776100429777 16920.27076783654 14862.551245210949 17800.324227918692 0.9195455905990432 1.300721566690307 0.7522596974962157 0.8901803941898946 1.0132855428320813 0.8375092573530224 0.7598050421585588 0.9505596949351156 0.8349595802249472 1.0 14.119615899266421 -5.271481537157005 24.998445541091776 0.8773934866055304 1.1101335910671968 0.36982180894327665 0.1202249183168629 595.6671483402394 1482825.6729770538 0.029805450122160865 0.06322035943675089 5.352029059765269e-06 5.271481537157005 0.23274010446166638 LNPYPTPS(ph)PPHPLYPGR ddPTM_PC-9_AZD4547_30min_R2 1 LNPYPTPSPPHPLYPGR 17 0 Q5JTD0-4;Q5JTD0-2;Q5JTD0 Q5JTD0-4 TJAP1 Tight junction-associated protein 1 1 LNPYPT(0.002)PS(0.995)PPHPLY(0.004)PGR 61.56100000000001 0.017999 4814400.0 33971.0 22367.0 21020.0 29596.0 28776.0 27438.0 19620.0 19578.0 22334.0 20927.0 True False 44773.071359304486 29596.69533947566 20741.26106577599 22773.099453641866 24780.949109916157 25722.29752251927 21366.141991023687 16552.669957683756 23514.529644235317 20194.35209968306 2.217108582552999 1.4655927158930822 1.027082273469002 1.1276964639038496 1.2271227612350624 1.2737372011515522 1.0580256244694781 0.819668285269897 1.1644111941875257 1.0 14.301664239996562 -4.797665344342934 2.232000516542194 1.0922325966070168 2.485701639445121 0.8871331153370999 0.12288632690091882 0.19799978131647056 1.1955780138409384 0.035268834867739976 0.5482290505436647 1.5934361131438393e-05 4.797665344342934 1.3934690428381042 up LNPYPTPS(ph)PPHPLYPGR ddPTM_PC-9_Lapatinib_30min_R1 1 LNPYPTPSPPHPLYPGR 17 0 Q5JTD0-4;Q5JTD0-2;Q5JTD0 Q5JTD0-4 TJAP1 Tight junction-associated protein 1 1 LNPY(0.003)PT(0.442)PS(0.555)PPHPLYPGR 135.23 1.4224000000000001e-06 0.0 5209.3 6578.8 6996.1 4826.0 4749.1 6537.1 4258.0 4490.5 5477.9 4261.7 True False 5135.014426731377 6563.567192800268 6420.907663726974 5180.920139064057 4469.767275089841 6257.523471724386 4478.458405445992 4699.145023376213 4860.921217155714 4998.329166641696 1.027346190203299 1.3131522502769124 1.2846108068631037 1.0365304017272319 0.894252284327447 1.251923045302101 0.895991091450066 0.9401431691889751 0.972509223601553 1.0 12.287230198380488 -5.863115634157403 5.737045738091814 0.9952450344409542 1.2176857288812455 0.3999880506838773 0.11822606296735994 0.19946272731050682 9.520076191643225 0.03340717968114746 0.05036926062742221 1.3705168072193978e-06 5.863115634157403 0.22244069444029124 LNQDQLDAVSK ddPTM_PC-9_Lapatinib_30min_R1 1 LNQDQLDAVSK 11 0 G3V153;Q14444-2;Q14444;E9PLA9 G3V153 CAPRIN1 Caprin-1 0 128.28 0.001464 3872000.0 20504.0 24791.0 26503.0 16148.0 19961.0 21341.0 23115.0 18914.0 19250.0 20090.0 False True 20211.60920002692 24733.597962654494 24324.025644538524 17335.577788148865 18786.933224835935 20428.295178300792 24311.78159743637 19792.813488951717 17081.862288513406 23562.529731757688 0.8577860454765015 1.049700445759796 1.0323180881446057 0.7357265109265365 0.7973224199061623 0.8669822557620984 1.0317984475439763 0.8400122446222262 0.7249587579507811 1.0 14.524206818358648 -5.739291028334839 24.99975005159737 0.8552715135715829 0.9869114411631451 0.22426725193185582 0.10477893199612477 354.6182687666817 400269.0379407254 0.029172147037433604 0.05047736072509983 1.8226738873069543e-06 5.739291028334839 0.13163992759156218 LNQPGT(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 3 LNQPGTPTR 9 0 P36507;G5E9C7;M0R1B6 P36507 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 1 LNQPGT(0.889)PT(0.111)R;LNQPGT(0.921)PT(0.079)R;LNQPGT(0.896)PT(0.104)R 114.71 0.0049458 316166000.0 275587.0 213932.0 346637.0 460210.0 433660.0 397278.0 296100.0 426820.0 312140.0 295108.0 True False 363217.933434302 283081.33533172554 342040.36689140747 354115.69467362214 373453.79451648094 372436.14385711 322452.3263782926 360864.77634786966 328639.0831535602 284776.3587438846 1.2754497425151936 0.9940478787648117 1.2010841363380997 1.2434869812774674 1.3113932496494518 1.3078197414275627 1.1323001944423767 1.267186566818967 1.1540251606669492 1.0 18.11946985761383 -8.579571245910707 7.369255304629098 1.0000010919204456 1.2128630396426052 0.34625181285800977 0.09002298169074335 1.253491450727096 162.43723591975396 0.09034872566708126 0.023365766964896704 2.6328659871805825e-09 8.579571245910707 0.2128619477221596 LNQPGT(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LNQPGTPTR 9 0 P36507;G5E9C7;M0R1B6 P36507 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 1 LNQPGT(0.897)PT(0.103)R;LNQPGT(0.977)PT(0.023)R;LNQPGT(0.988)PT(0.012)R;LNQPGT(0.972)PT(0.028)R;LNQPGT(0.999)PT(0.001)R;LNQPGT(0.899)PT(0.101)R 183.85 0.003208 2277250000.0 536937.0 571669.0 616460.0 632126.0 744545.0 692195.0 706313.0 636760.0 641472.0 543460.0 True False 627829.8291108495 628420.5202911987 631158.7443375692 596710.0296001422 598656.7520110036 655895.0756603446 639405.9193767103 620045.7247029872 650852.3144542057 641984.9959730069 0.977950938182436 0.9788710394060697 0.9831362855777818 0.9294765973397165 0.9325089461065454 1.0216672971714162 0.9959826528462901 0.9658258815896966 1.0138123453613728 1.0 19.29218005451292 -6.765193555058391 24.999933648512794 0.9971045634633335 0.9609619643518135 0.4424099290596769 0.02184592305147872 110.63341334553265 736727.6461497766 0.008205476563033385 0.00750887753168058 1.7171429255018472e-07 6.765193555058391 -0.03614259911152007 LNQPGT(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 3 LNQPGTPTR 9 0 P36507;G5E9C7;M0R1B6 P36507 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 1 LNQPGT(0.679)PT(0.321)R;LNQPGT(0.912)PT(0.088)R;LNQPGT(0.982)PT(0.018)R 124.39 0.0035708 1604660000.0 362059.0 293563.0 342829.0 312539.0 337405.0 346287.0 312536.0 315558.0 377063.0 262298.0 True False 356895.97226651164 292883.27290995634 314642.92297820916 335524.16065954 317559.5012637525 331477.1122444241 328717.58482960745 330219.9766811165 334594.1942905829 307635.85980988486 1.1601247412673832 0.9520452950151994 1.0227771338902252 1.0906536086751712 1.0322577525910026 1.077498287908545 1.0685281781933706 1.0734118476473722 1.0876306633997674 1.0 18.230864156392336 -5.74354735211958 24.958876096158058 1.0642348847049723 1.035688681822636 0.008570157690282021 0.05414775684846649 781.3237062261666 1089916.4749288221 0.013930323206101033 0.02406686833845299 1.8048979342574677e-06 5.74354735211958 -0.028546202882336225 LNQPGTPT(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 LNQPGTPTR 9 0 P36507;G5E9C7;M0R1B6 P36507 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 1 LNQPGT(0.224)PT(0.776)R;LNQPGT(0.206)PT(0.794)R 136.81 0.002398 1266490000.0 253560.0 233157.0 302470.0 424894.0 371061.0 257645.0 282586.0 357581.0 240242.0 305419.0 True False 334186.8056243637 308520.44061636046 298459.0501696125 326941.2528468613 319545.5851290871 241534.41742071116 307735.60655838053 302325.07284393214 252940.70165623652 294726.37377230916 1.1338883634572172 1.0468029605477653 1.012664887602448 1.1093043647985157 1.0842110295020697 0.8195208807723077 1.0441400361276174 1.0257822161429413 0.8582221482887915 1.0 18.1690166411357 LNQPGTPT(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 LNQPGTPTR 9 0 P36507;G5E9C7;M0R1B6 P36507 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 1 LNQPGT(0.322)PT(0.678)R 101.39 0.008588799999999999 852140000.0 90905.0 75853.0 94625.0 80139.0 88938.0 91996.0 84574.0 75868.0 98605.0 71763.0 True False 89608.67803006474 75677.3670388945 86845.2977630629 86032.689395867 83706.84169883572 88061.54553315023 88952.8278962399 79393.10424975095 87499.06654331756 84167.13893181324 1.0646515869175484 0.8991319890320069 1.031819530344489 1.0221648316401144 0.9945311526705164 1.0462699178178314 1.0568593518226124 0.9432791141216063 1.0395870366248712 1.0 16.360969456621753 LNQQPS(ph)QGLGPR ddPTM_PC-9_Lapatinib_30min_R1 2 LNQQPSQGLGPR 12 0 A2AB27;P36915 A2AB27 GNL1 Guanine nucleotide-binding protein-like 1 1 LNQQPS(1)QGLGPR;LNQQPS(1)QGLGPR 85.67200000000001 0.034268 2604600.0 19591.9 21949.0 24299.4 21863.0 21761.0 20670.7 25263.0 21434.0 23955.0 21924.4 True False 19312.515913285566 21898.178439042535 22301.597130396527 23470.877952830004 20481.060763772082 19786.662346755176 26570.99452719166 22429.901888664008 21256.935642666926 25714.003327573333 0.7510505333324197 0.8516051802622636 0.8672938572144596 0.9127663885639306 0.7964944432363076 0.7694897637948805 1.0333278015368135 0.8722835414978827 0.8266676865470007 1.0 14.650266615595125 -14.522878735715617 0.07064039629986525 1.4643885725753998 0.6914899917093749 0.3021249479880971 0.07342481577425784 429.18520530380687 2.1724142793512082 32.71776973747701 3.979835723364883 3.0000000660707507e-15 14.522878735715617 -0.7728985808660249 LNQS(ph)PSLAPVKR ddPTM_PC-9_AZD4547_30min_R2 1 LNQSPSLAPVKR 12 1 Q9H2P0;A0A669KBJ7;A0A2R8Y6X0 Q9H2P0 ADNP Activity-dependent neuroprotector homeobox protein 1 LNQS(0.691)PS(0.309)LAPVKR 122.66 0.00057366 8499100.0 27990.0 18433.0 32191.0 47403.0 35087.0 25960.0 27792.0 38065.0 25687.0 36910.0 True False 36890.23777183283 24391.10677303863 31764.126306774255 36474.97071904937 30215.775695705746 24336.7170961659 30265.434159761982 32182.928896681584 27044.762378950167 35617.79213452964 1.0357250003733278 0.684801199381269 0.8918050334731598 1.0240660224328935 0.8483337648100059 0.6832741626500956 0.8497279686918375 0.9035632746444682 0.7593048518224026 1.0 15.120310469394736 -4.713262811872207 23.970164581982623 0.8479812449675348 1.0357300703944252 0.2054171945286063 0.10988551936585522 15792.36340115904 7856344.594645816 0.027487642861268216 22.136461502105025 1.9352504990766543e-05 4.713262811872207 0.18774882542689042 LNQS(ph)PSLAPVKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LNQSPSLAPVKR 12 1 Q9H2P0;A0A669KBJ7;A0A2R8Y6X0 Q9H2P0 ADNP Activity-dependent neuroprotector homeobox protein 1 LNQS(0.989)PS(0.011)LAPVKR 65.51100000000001 0.019004 22044000.0 56719.0 43469.0 61384.0 74435.0 82896.0 79512.0 75175.0 66462.0 59180.0 49547.0 True False 66320.40644868618 47784.31504338711 62847.62736011633 70264.64827152604 66653.12387391512 75342.25074712382 68053.87978013163 64717.44292230979 60045.395542439575 58529.47888616378 1.1331111725370948 0.8164144966389442 1.0737773265050092 1.200500151525122 1.1387957853435073 1.2872530591577596 1.1627282708682956 1.105723887413746 1.0259000538724112 1.0 15.83687581332272 -5.515208936043835 23.934926323453187 1.1435185644630972 0.9673460813301078 0.2540488447111474 0.10507919033035217 217.1072522295318 677516.969500633 0.027420375448740306 0.05038156108761798 3.053451765466343e-06 5.515208936043835 -0.1761724831329894 LNQS(ph)PSLAPVKR ddPTM_PC-9_Lapatinib_30min_R1 1 LNQSPSLAPVKR 12 1 Q9H2P0;A0A669KBJ7;A0A2R8Y6X0 Q9H2P0 ADNP Activity-dependent neuroprotector homeobox protein 1 LNQS(0.98)PS(0.02)LAPVKR 57.703 0.032692 20760000.0 116520.0 87224.0 90186.0 81737.0 84813.0 82434.0 71983.0 70235.0 88557.0 65758.0 True False 114858.40343284873 87022.03818702673 82771.25520802758 87748.21164663872 79824.46608877357 78908.48998303953 75709.927524476 73498.37450547356 78582.7781134483 77124.18268297282 1.4892657456739147 1.128336601565557 1.0732205169456077 1.1377522405305365 1.035012149391593 1.0231355100047062 0.98166262371544 0.9529874022470548 1.0189122967626274 1.0 16.234895675053387 -1.5228787452803976 0.798689265788351 1.0089282543358065 115.66772441847405 0.9070484831898512 0.04462560216086502 146.3737969115348 0.5125244582536054 0.017297560053837084 30361.993027903678 0.029999999999995856 1.5228787452803976 114.65879616413825 LNQS(ph)SPDNVTDTK ddPTM_PC-9_AZD4547_30min_R2 4 LNQSSPDNVTDTK 13 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 LNQS(0.707)S(0.293)PDNVTDTK;LNQS(0.924)S(0.076)PDNVTDTK;LNQS(0.691)S(0.302)PDNVT(0.007)DTK;LNQS(0.94)S(0.06)PDNVTDTK 242.01 6.2241000000000006e-27 125978500.0 447545.0 424874.0 516889.0 660616.0 616889.0 492785.0 538151.0 612840.0 471641.0 541368.0 True False 589855.0004857065 562206.211636088 510034.7141307271 508321.1876154566 531244.6106292419 461971.07604908047 586045.3964633741 518139.6596622185 496570.9803858156 522414.87109959417 1.1290930505943721 1.0761680854389535 0.9763020586630528 0.9730220476793228 1.016901776764246 0.8842992449213978 1.1218007543120827 0.9918164438382523 0.9505299482394489 1.0 18.99483643976731 -5.076979674652595 3.156468876317853 0.9904669141532703 1.1241299198855204 0.40684185759806546 0.05624839805682346 0.2515458694519408 4.660841373936129 0.014507880999441126 0.056973431792718396 8.375684801196821e-06 5.076979674652595 0.1336630057322501 LNQS(ph)SPDNVTDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LNQSSPDNVTDTK 13 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 LNQS(0.977)S(0.023)PDNVTDTK 106.55 0.001106 13945000.0 70332.0 61418.0 67344.0 76089.0 91998.0 67568.0 72543.0 79579.0 64798.0 65948.0 True False 82237.8184796804 67515.1731425785 68949.7363635423 71825.9800138663 73971.65231316884 64024.61513333406 65671.20187416153 77490.1355709201 65745.54816422773 77903.85035591914 1.055632271113182 0.8666474485423002 0.8850619840807841 0.921982414036214 0.9495249846472893 0.8218414730571717 0.8429776137396247 0.9946894180055427 0.8439319477003536 1.0 16.24940701402528 -4.75390698845683 24.985234220372465 0.8998765527765257 1.0556325496294583 0.3688513950089739 0.059789826825028425 284.6696989156096 944182.4704039438 0.014328799184305808 0.14695788763288978 1.762353443934443e-05 4.75390698845683 0.15575599685293262 LNQS(ph)SPDNVTDTK ddPTM_PC-9_Lapatinib_30min_R1 2 LNQSSPDNVTDTK 13 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 LNQS(0.723)S(0.277)PDNVTDTK;LNQS(0.679)S(0.321)PDNVTDTK 182.37 6.9977e-05 88377000.0 393812.0 401705.0 429779.0 369801.0 461343.0 414878.0 431883.0 376130.0 381122.0 328355.0 True False 388196.1686637246 400774.87675318227 394444.2296149157 396997.39915997186 434207.7117752353 397134.63506785454 454243.78852025146 393606.3729300729 338196.02696741855 385110.72424446524 1.008011837180885 1.040674412636646 1.0242359009574753 1.0308656034931944 1.1274879779759228 1.0312219579108803 1.1795147730861453 1.0220602755279666 0.8781786786927658 1.0 18.55491377310763 -8.011241326701844 24.934254899856573 0.9427660210415485 1.063646365706442 0.42742814353263614 0.05678953172988751 474.26859107595897 1051963.6973420973 0.034078639953350386 0.014533275790407946 9.744480105892342e-09 8.011241326701844 0.12088034466489361 LNQSS(ph)PDNVTDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LNQSSPDNVTDTK 13 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 LNQS(0.226)S(0.773)PDNVT(0.002)DTK 199.33 5.5365e-07 14411000.0 64481.0 51932.0 56272.0 70311.0 70474.0 54764.0 67356.0 55792.0 52598.0 50826.0 True False 75396.35974219804 57087.465753368626 57613.73789274838 66371.70262133758 56665.12560184192 51892.07943348784 60975.5520647896 54327.519116510346 53367.1462443602 60040.35146160534 1.2557614655272724 0.9508183140779075 0.9595836215181263 1.1054516005586845 0.9437840422716077 0.8642867366736158 1.0155762013448955 0.9048501181951234 0.8888546609939062 1.0 15.873644801718427 -4.76046174682589 24.99793946626153 0.9591608640776415 1.255761814985542 0.6455291657705016 0.06591771601342489 15.85853663936173 405294.9289513536 0.01696284456384545 0.10040705412656951 1.73595416104325e-05 4.76046174682589 0.2966009509079006 LNQSS(ph)PDNVTDTK ddPTM_PC-9_Lapatinib_30min_R1 2 LNQSSPDNVTDTK 13 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 LNQS(0.483)S(0.517)PDNVTDTK;LNQS(0.243)S(0.757)PDNVTDTK 225.6 1.7764e-19 87734100.0 435532.0 361981.0 405344.0 376009.0 432311.0 426376.0 369100.0 390635.0 420770.0 333094.0 True False 429321.233813213 361142.85523454595 372018.1809930881 403661.95618925395 406883.31693612784 408140.89241100167 388210.1919798296 408785.32818317955 373378.4516954688 390668.8540801434 1.09893898458857 0.9244219278367649 0.9522596365380354 1.0332586075736796 1.041504365363762 1.0447233971901788 0.9937065315685252 1.046372967575551 0.955741538635359 1.0 18.575586716251593 -1.630334446424334 13.797531511062687 1.0085842028954144 1.0603663100262533 0.0 0.050925149137011426 0.0 0.0 0.011521261592846077 0.0 0.023424242399174372 1.630334446424334 0.05178210713083886 LNRS(ph)NSELEDEILCLEK ddPTM_PC-9_AZD4547_30min_R2 1 LNRSNSELEDEILCLEK 17 1 Q96PC5;Q96PC5-11;Q96PC5-13;G3V599;Q96PC5-10;Q96PC5-9;Q96PC5-6;Q96PC5-12;Q96PC5-7;Q96PC5-14;Q96PC5-5;Q96PC5-8;Q86UF2;A0A5F9ZHA4;G3V5K6;P0CG41;A4D2H0;A0A2R8YE69;Q8IX94 Q96PC5 MIA2;CTAGE6;CTAGE5;CTAGE8;CTAGE15;CTAGE4 Melanoma inhibitory activity protein 2;cTAGE family member 6;cTAGE family member 8;cTAGE family member 15;cTAGE family member 4 1 LNRS(0.819)NS(0.181)ELEDEILCLEK 105.96 0.00032460000000000003 2705600.0 24454.0 25530.0 38703.0 43933.0 36530.0 24057.0 31175.0 29810.0 20387.0 29564.0 True False 32229.863325201863 33782.073233639465 38189.77293190904 33804.92560808378 31458.440053698836 22552.711986997812 33949.514606022596 25203.5494656529 21464.6151991146 28528.97335858127 1.129723909798787 1.1841321034946428 1.338631168107628 1.1849331268668155 1.1026839156914985 0.7905195782383159 1.1900012727170526 0.8834369589423691 0.7523795171079379 1.0 14.800140210691543 -6.541440926542048 4.626378472497438 0.9320399967148876 1.2107598123455223 0.5480535190362879 0.1228748006303934 0.1580989672246375 8.587700539656076 0.04156546371115452 0.04311872190671599 2.874478558380279e-07 6.541440926542048 0.27871981563063475 LNRSNS(ph)ELEDEILCLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LNRSNSELEDEILCLEK 17 1 Q96PC5;Q96PC5-11;Q96PC5-13;G3V599;Q96PC5-10;Q96PC5-9;Q96PC5-6;Q96PC5-12;Q96PC5-7;Q96PC5-14;Q96PC5-5;Q96PC5-8;Q86UF2;A0A5F9ZHA4;G3V5K6;P0CG41;A4D2H0;A0A2R8YE69;Q8IX94 Q96PC5 MIA2;CTAGE6;CTAGE5;CTAGE8;CTAGE15;CTAGE4 Melanoma inhibitory activity protein 2;cTAGE family member 6;cTAGE family member 8;cTAGE family member 15;cTAGE family member 4 1 LNRS(0.181)NS(0.819)ELEDEILCLEK;LNRS(0.376)NS(0.624)ELEDEILCLEK 93.006 0.0042324 0.0 21056.4 14548.7 18354.199999999997 20976.0 30886.0 19790.1 20601.5 24812.0 22469.0 19021.2 True False 24620.832637143023 15992.998786991335 18791.833736691122 19800.78272510956 24834.110017006147 18752.272317520034 18649.976778056323 24160.71129048707 22797.56661782825 22469.592988263656 1.0957400363238892 0.7117618372235233 0.836322836221666 0.8812256962309877 1.1052318584487726 0.8345621715228551 0.8300095505867686 1.0752625249200873 1.0145963315728908 1.0 14.455686371484637 -7.767177091305811 24.99394035777429 1.033697088889834 0.8943717813222185 0.21160830804016573 0.11525960849303171 217.14987742499008 945900.6217010213 0.061284923021269 0.03070638810375109 1.7093181680525342e-08 7.767177091305811 -0.13932530756761552 LNRSNS(ph)ELEDEILCLEK ddPTM_PC-9_Lapatinib_30min_R1 1 LNRSNSELEDEILCLEK 17 1 Q96PC5;Q96PC5-11;Q96PC5-13;G3V599;Q96PC5-10;Q96PC5-9;Q96PC5-6;Q96PC5-12;Q96PC5-7;Q96PC5-14;Q96PC5-5;Q96PC5-8;Q86UF2;A0A5F9ZHA4;G3V5K6;P0CG41;A4D2H0;A0A2R8YE69;Q8IX94 Q96PC5 MIA2;CTAGE6;CTAGE5;CTAGE8;CTAGE15;CTAGE4 Melanoma inhibitory activity protein 2;cTAGE family member 6;cTAGE family member 8;cTAGE family member 15;cTAGE family member 4 1 LNRS(0.403)NS(0.597)ELEDEILCLEK 66.809 0.009262200000000002 1913800.0 9642.2 10478.0 7321.0 4985.4 7854.3 7502.6 7087.9 6033.5 9203.3 4664.9 True False 9504.70045983708 10453.738834766405 6719.095639877238 5352.04294680687 7392.3255161479265 7181.731287414818 7454.87678063895 6313.83843637465 8166.727438954565 5471.221749411466 1.737217187524796 1.9106772332689503 1.2280795675298675 0.9782171500145437 1.3511288437437419 1.312637581941794 1.3625616218974974 1.1540088714287304 1.4926697935124 1.0 12.41764731420693 -5.265777507304465 24.958661013519485 1.2427308540054318 1.8239472350536972 0.6931976502226833 0.15667871660875363 173.9911618128233 1001033.4102163861 0.03993773237730819 0.08808988361658776 5.4227863312997985e-06 5.265777507304465 0.5812163810482653 LNS(ph)GGGLSEELGSAR ddPTM_PC-9_Lapatinib_30min_R1 1 LNSGGGLSEELGSAR 15 0 A0A0G2JIS2;A2ABF8;A0A0G2JIR1;A2ABF9;A0A0G2JK64;Q96KQ7-2;Q96KQ7 A0A0G2JIS2 EHMT2 Histone-lysine N-methyltransferase EHMT2 1 LNS(0.995)GGGLS(0.004)EELGS(0.001)AR 72.48899999999999 0.019536 4551400.0 14688.0 17971.0 10910.0 12770.0 11466.0 9645.9 10289.0 9414.2 13582.0 7604.3 True False 14478.54642655068 17929.389253634945 10013.021913817884 13709.148399471213 10791.59242302333 9233.367342691143 10821.714075536347 9851.618100226771 12052.252135199426 8918.693122907162 1.6233932737704977 2.0103157499145605 1.122700576847969 1.5371252503643202 1.209997056105197 1.0352825481769026 1.2133744177991037 1.1046033274677256 1.3513473296041427 1.0 13.122616608795107 LNS(ph)PPSSIYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LNSPPSSIYK 10 0 C9JKH7;Q53EP0-2;Q53EP0 C9JKH7 FNDC3B Fibronectin type III domain-containing protein 3B 1 LNS(0.755)PPS(0.189)S(0.056)IYK 78.548 0.020245 13247000.0 55623.0 46186.0 38219.0 43208.0 70108.0 35745.0 44893.0 33792.0 33567.0 32849.0 True False 65038.875295672944 50771.04084735966 39130.28590636464 40787.19584222605 56370.84067448896 33870.469274523835 40640.41004282613 32904.99580558359 34057.853872474974 38804.26366745909 1.6760754914211649 1.308388203998722 1.0084017117732078 1.0511008839585283 1.4526970839485622 0.8728543225245454 1.0473181604759276 0.8479737197842366 0.877683291824336 1.0 15.243927558610125 -1.5228787452803376 0.542538861021649 0.972086952666191 29.73471352277576 0.6246918914361967 0.16042646933745672 91.48495668032805 0.8577902673151921 0.08489597708123041 3057.2560048632863 0.029999999999999995 1.5228787452803376 28.762626570109568 LNS(ph)PPSSIYK ddPTM_PC-9_Lapatinib_30min_R1 1 LNSPPSSIYK 10 0 C9JKH7;Q53EP0-2;Q53EP0 C9JKH7 FNDC3B Fibronectin type III domain-containing protein 3B 1 LNS(0.513)PPS(0.401)S(0.086)IYK 94.68799999999999 0.006206199999999999 17058000.0 95223.0 97653.0 45257.0 32379.0 41129.0 44074.0 43462.0 35803.0 51264.0 18423.0 True False 93865.10255824032 97426.89047828248 41536.14415707204 34760.259673177614 38709.873082725164 42189.05776151208 45712.249698800755 37466.53808527746 45490.108486148114 21607.391002895554 4.344120146002897 4.5089613301868114 1.9223118678005078 1.6087208154154047 1.7915107417428484 1.9525290099049175 2.115583954243942 1.7339686258399574 2.105303156686159 1.0 14.399237263203716 -5.270123662956064 7.553601440209997 1.8150228631633656 4.433264303833039 0.9233109298233924 0.30511586135483915 0.027871985403500266 12.55970466287066 0.07433339247913129 0.16900326805915733 5.36878901300134e-06 5.270123662956064 2.6182414406696735 LNS(ph)SENGEDR ddPTM_PC-9_AZD4547_30min_R2 1 LNSSENGEDR 10 0 Q7L4I2;H0YGP9;E1B6W4;Q7L4I2-2 Q7L4I2 RSRC2 Arginine/serine-rich coiled-coil protein 2 1 LNS(0.968)S(0.032)ENGEDR 107.65 0.0021421 85126000.0 16010.0 14654.0 19332.0 22548.0 23380.0 16373.0 16854.0 23782.0 15940.0 20580.0 True False 21100.846971312727 19390.618925411396 19075.645048695587 17349.90696312734 20134.09056817626 15349.193721707412 18353.973349475717 20107.038355993212 16782.555857845033 19859.500464064477 1.0625064315940098 0.9763900638134622 0.9605299530676884 0.8736325968783447 1.0138266370097602 0.7728892148864263 0.9241910884257641 1.0124644571184784 0.8450643503452094 1.0 14.277541714043096 -4.646901206467711 1.1834865186429284 0.9186441115202201 1.1617072500608756 0.2527960692900677 0.07358972973758916 2.771068722847414 2.687601668627422 0.021752006761347222 0.898178328208445 2.2547520659786548e-05 4.646901206467711 0.24306313854065553 LNS(ph)SENGEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LNSSENGEDR 10 0 Q7L4I2;H0YGP9;E1B6W4;Q7L4I2-2 Q7L4I2 RSRC2 Arginine/serine-rich coiled-coil protein 2 1 LNS(0.915)S(0.085)ENGEDR 97.95700000000001 0.0049447 2192400.0 4970.1 5760.1 4340.9 6140.3 8306.2 6073.1 10042.0 7221.4 5017.9 7381.4 True False 5811.4397660504455 6331.924660825277 4444.403518954925 5796.278898121194 6678.659736555611 5754.615944918471 9090.749062215937 7031.845901705763 5091.277294565859 8719.589388869754 0.666480897996016 0.7261723434944946 0.5097033037619924 0.6647421844794594 0.7659374127273335 0.6599640978810348 1.0425661870982084 0.8064423206305638 0.5838895695093961 1.0 13.09004448381692 -6.753892437634351 1.716927164963652 0.83501905488731 0.6445344677407736 0.29385789012236085 0.13529959840712713 0.4963427742476611 3.0282341799290426 0.057674107696054196 0.05290776360315963 1.7624124917067957e-07 6.753892437634351 -0.19048458714653638 LNS(ph)SENGEDR ddPTM_PC-9_Lapatinib_30min_R1 2 LNSSENGEDR 10 0 Q7L4I2;H0YGP9;E1B6W4;Q7L4I2-2 Q7L4I2 RSRC2 Arginine/serine-rich coiled-coil protein 2 1 LNS(0.904)S(0.096)ENGEDR;LNS(0.974)S(0.026)ENGEDR 176.99 0.0016351 123089000.0 38376.6 34301.0 44284.0 38943.5 47526.0 47071.6 37762.0 42526.0 46708.0 42797.0 True False 37829.34264659349 34221.578141947146 40643.140461183386 41807.53490170766 44730.61411971105 45058.457397259 39717.131589114964 44501.913208795646 41447.25318295503 50194.40442658208 0.7536565694673276 0.6817807389666725 0.809714567300643 0.8329122614226522 0.8911474223214908 0.8976788929364571 0.7912661190593083 0.8865911194122709 0.825734534684613 1.0 15.615238923885478 -1.5228787452803376 0.12604444954110106 1.002928083710692 0.08754452448026882 0.6172170349329849 0.05163819821137827 63.47433222039864 0.5468903312312484 0.3241914628107722 10.269882804044475 0.029999999999999995 1.5228787452803376 -0.9153835592304231 LNS(ph)SNSASPHR ddPTM_PC-9_AZD4547_30min_R2 1 LNSSNSASPHR 11 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 LNS(0.5)S(0.5)NSASPHR 84.75299999999999 0.0067079999999999996 6144700.0 5019.1 3874.1 7084.2 12869.0 11582.0 7274.2 6590.5 9065.4 7612.1 10286.0 True False 6615.0693962345895 5126.327062845384 6990.258879265952 9902.25087406802 9974.039219872424 6819.343124072805 7177.041732509769 7664.5507321680625 8014.4600655898475 9925.890270814738 0.6664459525293152 0.5164601786822497 0.7042450287627627 0.9976184104295184 1.0048508443821165 0.6870258423190345 0.7230627718717126 0.7721776609504005 0.8074298472908671 1.0 13.276980790614223 -5.527165655206916 23.83529632760058 0.8409799148845595 0.5961779068291263 0.46673675021830996 0.11464504698303563 60.79699898023928 338030.7576445593 0.03334940007994168 0.05811644834388563 2.9705327498316448e-06 5.527165655206916 -0.24480200805543317 LNSEAS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 2 LNSEASPSR 9 0 Q13111;Q13111-3;Q13111-2;K7EJF1 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 LNS(0.008)EAS(0.933)PS(0.059)R;LNS(0.092)EAS(0.454)PS(0.454)R 85.973 0.012022 68113000.0 101264.0 136539.0 138818.0 84118.0 108183.0 151855.0 152262.0 161135.0 142426.0 105877.0 True False 133463.84557795242 180672.56158432833 136977.18261793014 64725.894710144865 93163.65782450885 142359.4828443096 165813.0230294214 136235.28826393737 149954.34759155818 102170.27845645072 1.306288360903708 1.7683475499319363 1.3406754360204234 0.633510015711015 0.911846960113935 1.393355141974965 1.6229085946956472 1.3334140840382127 1.4676905050765332 1.0 16.640616048797533 -6.944850453375274 24.999678097533625 1.40155516025765 1.1964867052625314 0.06337647755484233 0.31258521037981324 256.87246729605926 116440.78122064864 0.12222665954228332 0.10779378783729583 1.1354017169406722e-07 6.944850453375274 -0.2050684549951185 LNSEAS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LNSEASPSR 9 0 Q13111;Q13111-3;Q13111-2;K7EJF1 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 LNS(0.002)EAS(0.936)PS(0.062)R;LNS(0.005)EAS(0.498)PS(0.498)R 91.09299999999999 0.0080671 55510000.0 70340.0 132861.0 116744.0 79854.0 100510.0 53761.0 93281.0 56830.0 61651.0 65310.0 True False 82247.1727216733 146050.56203224018 119527.6197140856 75380.0392701612 80815.78701707226 50941.67851916841 84444.74838404353 55338.2727163623 62552.52924276684 77150.18600632444 1.0660657735151933 1.8930681777004088 1.5492849194723552 0.9770558332028113 1.0475125362685105 0.6602923616411298 1.0945501593103237 0.7172798353567924 0.8107890917805312 1.0 16.235382014635523 -5.803954548004178 4.360807961698734 0.8853600229904152 1.5470475436562297 0.5934279233063934 0.22811981625470473 0.12602307245639832 5.153044165978778 0.06251449510352028 0.09952513777400437 1.5705271625322741e-06 5.803954548004178 0.6616875206658145 LNSEAS(ph)PSREAINGQR ddPTM_PC-9_Lapatinib_30min_R1 1 LNSEASPSREAINGQR 16 1 Q13111;Q13111-3;Q13111-2;K7EJF1 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 LNSEAS(0.988)PS(0.012)REAINGQR 170.16 0.0001463 6392800.0 17053.0 13306.0 18614.0 15143.0 14301.0 14016.0 12143.0 10506.0 18076.0 13013.0 True False 16809.821092862796 13275.190774518196 17083.628772117867 16256.666735567147 13459.843296847788 13416.568352891805 12771.705123844675 10994.147114038631 16040.09053128147 15262.279711267429 1.1013964762061652 0.8698039235067709 1.1193366322270861 1.0651532433628252 0.8819025434916524 0.8790671254037481 0.836815034546636 0.7203476362657779 1.0509629514547436 1.0 13.897682851715079 -6.2707446316014295 22.840956040456668 0.8771757527695495 1.032586525860509 0.3002552555311677 0.10552578485029258 237.2294341408492 582309.3739063989 0.03177594162290284 0.036599700889648826 5.36111802593916e-07 6.2707446316014295 0.1554107730909594 LNSEASPS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 LNSEASPSR 9 0 Q13111;Q13111-3;Q13111-2;K7EJF1 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 LNS(0.009)EAS(0.046)PS(0.945)R 80.87100000000001 0.018058 8466700.0 26779.0 38868.0 35560.0 23836.0 31326.0 39340.0 39404.0 37870.0 34534.0 28887.0 True False 35294.164962197625 51431.32089483346 35088.45116550876 18340.97846252897 26976.925626120163 36880.06358101565 42910.87966433729 32018.061666027348 36359.396737441675 27875.674922518487 1.2661277282182088 1.845025135276143 1.2587480397528836 0.6579563907782834 0.9677586534174891 1.3230195747197229 1.539366482914216 1.1486022044317414 1.3043413958049095 1.0 14.766719115365627 -5.506406058958123 24.75046671389808 1.1430225373064862 1.5546540704862921 0.2920569823112483 0.25875996804628604 808.3632511414606 1214576.2355425474 0.07271181839041636 0.1452120879673913 3.115974831006466e-06 5.506406058958123 0.41163153317980594 LNSEASPS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LNSEASPSR 9 0 Q13111;Q13111-3;Q13111-2;K7EJF1 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 LNSEAS(0.014)PS(0.986)R 95.477 0.0054135 10401000.0 28886.0 41275.0 42256.0 24364.0 35962.0 25226.0 31885.0 21911.0 22501.0 16258.0 True False 33775.8292754941 45372.50922302799 43263.54329677243 22998.964069153757 28915.50425537705 23903.10415216499 28864.62197259062 21335.8594666235 22830.03455729018 19205.446701742825 1.75865887422598 2.3624813277011985 2.2526705037715375 1.1975229957586295 1.5055887376341563 1.2446002700887904 1.502939370317862 1.1109275299848844 1.1887270789290434 1.0 14.229227899622247 -5.762481804107572 24.999998273234482 1.2756238407298202 2.148391476541578 0.7878336438275848 0.2075724586684414 11.510466035750335 276062.86048722133 0.056340717535791514 0.08924592523420476 1.7278983737700655e-06 5.762481804107572 0.8727676358117578 LNSEASPS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 LNSEASPSR 9 0 Q13111;Q13111-3;Q13111-2;K7EJF1 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 LNSEAS(0.04)PS(0.959)R 99.73200000000001 0.004046500000000001 7740500.0 21621.0 41783.0 41379.0 35302.0 44959.0 41281.0 43289.0 55686.0 34840.0 32657.0 True False 21312.6805751942 41686.25403063985 37976.97834755911 37898.22684401977 42314.60001279489 39515.507860711055 45530.292605296265 58273.374851737615 30915.95231853541 38301.71893728274 0.5564418821539762 1.0883650965874176 0.9915215139494032 0.9894654312010469 1.1047702606267633 1.0316901945162262 1.1887271346711612 1.521429754814856 0.8071687949347345 1.0 15.22512151965386 -4.5208293669273605 2.214691150425176 1.0997555393163336 1.3778678642073239e-08 0.4324834229357726 0.17724890495220813 1.837597765866997 5.053036961981428 0.04659403796890665 5.252097032039223 3.0141900583111007e-05 4.5208293669273605 -1.099755525537655 LNSEASPS(ph)REAINGQR ddPTM_PC-9_Lapatinib_30min_R1 1 LNSEASPSREAINGQR 16 1 Q13111;Q13111-3;Q13111-2;K7EJF1 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 LNS(0.016)EAS(0.035)PS(0.949)REAINGQR 84.821 0.023548 9201200.0 12021.0 12838.0 17298.0 12453.0 11513.0 9583.6 6783.6 9114.7 19614.0 10413.0 True False 11849.578335618591 12808.274399764361 15875.82521221096 13368.835161990202 10835.82797542889 9173.731768462749 7134.821615590283 9538.20223684827 17404.864775423477 12212.873175549657 0.9702531226920142 1.04875193704678 1.2999254953367225 1.0946511086969115 0.8872464177489675 0.7511526269533927 0.5842050034445863 0.78099576567649 1.4251244997997898 1.0 13.576115025287795 -6.259926704825079 5.245068459492667 0.8690381001824045 1.1151362059968464 0.15107492921286436 0.22111117929490268 0.29660766368843156 27.894527457232883 0.07069886870014731 0.08629518935107179 5.496336268057511e-07 6.259926704825079 0.24609810581444191 LNSHMNALHLGSQANR ddPTM_PC-9_AZD4547_30min_R2 1 LNSHMNALHLGSQANR 16 0 P11413;P11413-2;P11413-3;E7EUI8;E7EM57;E9PD92 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 69.069 0.012341 6064700.0 7967.3 5879.2 14596.0 30589.0 17746.0 14625.0 10840.0 18319.0 12981.0 13400.0 False True 10500.735669865082 7779.5364259778 14402.447503143028 23537.17864533891 15282.274218257315 13710.496438036456 11804.739000137457 15488.219478741888 13667.14915876326 12930.870078642569 0.812067216359149 0.601625132621738 1.11380343438227 1.8202316241823806 1.1818442320829186 1.0602918716723917 0.9129114226918805 1.1977708680503407 1.056939639455258 1.0 13.658531732494263 -5.329642285589779 6.018612544123278 1.1885301358208877 0.7084204578606259 0.37333248402928043 0.2386736210189911 0.21867936920000702 14.8713937864833 0.06718654809003446 0.14359010876282718 4.68120558400112e-06 5.329642285589779 -0.4801096779602618 LNSHMNALHLGSQANR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LNSHMNALHLGSQANR 16 0 P11413;P11413-2;P11413-3;E7EUI8;E7EM57;E9PD92 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ; 81.71300000000001 0.0038926000000000004 11361100.0 36274.0 34380.0 75264.0 57192.0 81821.0 74023.0 64414.0 61819.0 69676.0 52160.0 False True 42414.47175584274 37793.0191904955 77058.57920030945 53987.717658965725 65788.76240696314 70141.10356995594 58312.23960302498 60196.31675264473 70694.87968595838 61616.19510166722 0.6883656429264825 0.613361781397516 1.2506221631043946 0.8761936300981512 1.067718678480733 1.138354996672913 0.9463784562939875 0.9769560852194836 1.1473425058024316 1.0 15.911021975957238 -5.245357922255002 24.987465503628613 1.043439335786436 0.650863633581306 0.6990139838122107 0.10480020565617405 420.58509640417867 653505.2592107499 0.02538005935604179 0.06668861880297386 5.683843058553209e-06 5.245357922255002 -0.39257570220513005 LNSHMNALHLGSQANR ddPTM_PC-9_Lapatinib_30min_R1 2 LNSHMNALHLGSQANR 16 0 P11413;P11413-2;P11413-3;E7EUI8;E7EM57;E9PD92 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ; 86.411 0.0018894000000000003 10164300.0 29620.0 22345.8 32211.0 30567.0 36960.0 34730.0 29809.0 32754.0 39039.0 24648.5 False True 29197.613368357266 22294.05967302185 29562.73591805569 32814.99914852283 34786.0854661558 33244.678859584215 31352.36416344282 34275.870414355726 34642.01672110517 28908.960382938243 1.0099848967792484 0.771181646718073 1.022614979108806 1.135115158547517 1.203297697508561 1.1499783603150553 1.0845206381737147 1.1856486694895114 1.1983141649587132 1.0 14.819229107446123 -5.5546210667434845 3.633815597850986 1.1448460426125469 0.8890736096416892 0.6066022137854578 0.07887115286351158 0.12809954983830646 3.5813417447038214 0.020568077114353423 0.04046959184056097 2.7885531928251108e-06 5.5546210667434845 -0.2557724329708576 LNSPPS(ph)SIYK ddPTM_PC-9_AZD4547_30min_R2 1 LNSPPSSIYK 10 0 C9JKH7;Q53EP0-2;Q53EP0 C9JKH7 FNDC3B Fibronectin type III domain-containing protein 3B 1 LNS(0.329)PPS(0.537)S(0.134)IYK 83.617 0.013297999999999999 18865000.0 41438.0 35172.0 41526.0 48032.0 42115.0 31151.0 48603.0 39406.0 38344.0 39617.0 True False 54614.422036056036 46540.6611740528 40975.3381073936 36958.9644870025 36268.05920781619 29203.123045557153 52928.572843513 33316.708159795984 40370.7855591725 38230.02088847633 1.4285742138456026 1.2173851881959488 1.07181050794939 0.9667524010729233 0.9486800782457452 0.7638793379356967 1.384476691705582 0.8714802499581851 1.0559969526812754 1.0 15.222418367995434 -4.947904598691826 1.5918287100738415 0.9981571399478059 1.5073511271553148 0.44631480924782807 0.15117934361309884 0.686242647390944 2.14359007680329 0.04249032725846106 0.496284326285622 1.1274450944220105e-05 4.947904598691826 0.509193987207509 LNSS(ph)ENGEDRHK ddPTM_PC-9_Lapatinib_30min_R1 1 LNSSENGEDRHK 12 1 Q7L4I2;H0YGP9;E1B6W4;Q7L4I2-2 Q7L4I2 RSRC2 Arginine/serine-rich coiled-coil protein 2 1 LNS(0.399)S(0.601)ENGEDRHK 54.276 0.036042000000000005 2025800.0 34735.0 12256.0 18806.0 14137.0 17333.0 16460.0 14004.0 13084.0 30394.0 14676.0 True False 34239.672530381125 12227.621985006395 17259.8432732593 15176.682139649527 16313.507017989134 15756.044170134062 14729.058597901754 13691.930405490337 26970.70765699097 17212.727045459225 1.9892067328990537 0.7103826112337082 1.002737290126988 0.8817128221209541 0.9477584217134665 0.9153717553599712 0.8557074401401914 0.7954538737138874 1.5669049759379023 1.0 14.071188063986536 -4.753243809681658 24.996215243836993 0.9508384042899432 1.9892086463173633 0.6622168334727865 0.2194783983504836 175.71571500577156 535885.3393566046 0.05188612000385653 0.5699001297753081 1.7650466584724655e-05 4.753243809681658 1.0383702420274201 LNSS(ph)IVEPK ddPTM_PC-9_AZD4547_30min_R2 1 LNSSIVEPK 9 0 Q00653-3;Q00653-4;Q00653 Q00653-3 NFKB2 Nuclear factor NF-kappa-B p100 subunit;Nuclear factor NF-kappa-B p52 subunit 1 LNS(0.094)S(0.906)IVEPK 103.44 0.0028554 2373300.0 19244.0 23699.0 21992.0 19577.0 19567.0 31090.0 28725.0 29043.0 24706.0 25325.0 True False 25363.191699933934 31359.238290796 21700.37171068248 15063.8251116349 16850.45980100533 29145.937385200235 31281.469352301516 24555.071691746307 26011.908721701337 24438.37945833007 1.0378426173135074 1.28319630785121 0.8879627942468047 0.6164003279071862 0.6895080678216444 1.1926297091383262 1.2800140617195839 1.004774957914669 1.06438762709509 1.0 14.576861000837628 -6.790370462101172 24.999785276655984 1.119388042770812 0.9073492143409678 0.2291581784812744 0.18771025161791718 368.8368400560353 318714.89979743614 0.07547881384182482 0.06657685438282966 1.6204272499622858e-07 6.790370462101172 -0.21203882842984423 LNSS(ph)NSASPHR ddPTM_PC-9_AZD4547_30min_R2 1 LNSSNSASPHR 11 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 LNS(0.185)S(0.815)NSASPHR 94.71700000000001 0.0036937 4397600.0 1707.7 3591.8 7984.2 7142.7 9752.5 8594.8 7527.5 9615.9 7044.4 6227.7 True False 2250.713077633401 4752.779108522765 7878.324291216396 5496.060868614936 8398.533715403719 8057.365797308426 8197.43291730025 8129.983606399586 7416.752602572367 6009.670118564351 0.37451524513479845 0.7908552407628916 1.3109412223608785 0.9145361991895637 1.3975032821618574 1.340733457634984 1.3640404141281774 1.3528169510145687 1.2341363928880933 1.0 12.553070085686226 -4.808078858634065 1.282295790395175 1.274459541945506 2.731111874488046e-15 0.7535595611435068 0.15762946808220854 0.6168174481742985 0.91370104188549 0.04601148322863168 1.0300727901237352 1.555683127013897e-05 4.808078858634065 -1.2744595419455034 down LNSSNSAS(ph)PHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LNSSNSASPHR 11 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 LNSSNS(0.003)AS(0.997)PHR;LNSSNS(0.001)AS(0.999)PHR 95.195 0.0035814 5362800.0 15030.900000000001 35934.0 53499.0 39510.0 47038.0 34604.0 45145.0 28693.0 31380.0 25894.0 True False 17575.33449619277 39501.29004046728 54774.619056087344 37296.38279314826 37821.241565108336 32789.30532313954 40868.53877850414 27939.83915274649 31838.873134872494 30588.377223208776 0.5745755771201086 1.291382336245542 1.7907003910795039 1.2192991645483506 1.2364579293997873 1.0719530847900234 1.3360806452816771 0.9134135802257362 1.0408814074227812 1.0 14.900695950514539 -7.765457892362288 24.979826661345193 0.9828605871671863 1.2373515533881778 0.12223305528809236 0.2818333169195804 216.30165111175236 1344530.5581995838 0.15212685916395363 0.07731559238874508 1.71609808878029e-08 7.765457892362288 0.25449096622099154 LNSSNSAS(ph)PHR ddPTM_PC-9_Lapatinib_30min_R1 1 LNSSNSASPHR 11 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 LNSSNS(0.005)AS(0.995)PHR 72.615 0.015184 3018500.0 6099.1 11244.0 13800.0 11497.0 13382.0 15910.0 13938.0 14321.0 15955.0 10096.0 True False 6012.125715562046 11217.965208829297 12665.417269540487 12342.527732867698 12594.89707002427 15229.566388021452 14659.641440842228 14986.405941380857 14157.979886401616 11841.080147925615 0.5077345681690435 0.9473768498049159 1.069616716660708 1.042348128606319 1.0636611620461596 1.2861636098873506 1.2380324478599516 1.2656282834135075 1.195666249153958 1.0 13.531513069720543 -4.557000464941782 0.9462191038474366 1.1849057643171008 3.258343126458885e-27 0.8123307804427073 0.09343707006205691 1.259663887037889 0.6740463742284721 0.032487293534865215 1.693325157942608 2.7733171356256245e-05 4.557000464941782 -1.1849057643171008 LNSSSSSSSNSSNEREDFDS(ph)TSSSSSTPPLQPR ddPTM_PC-9_Lapatinib_30min_R1 1 LNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPR 33 1 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 LNSSSSSSSNSSNEREDFDS(0.125)T(0.125)S(0.125)S(0.125)S(0.125)S(0.125)S(0.125)T(0.125)PPLQPR 66.19 1.5723e-05 20118000.0 40665.0 25499.0 39722.0 32567.0 34964.0 34581.0 28461.0 26438.0 43191.0 23280.0 True False 40085.1096429523 25439.958632153888 36456.21049135415 34962.085820327215 32907.486261868806 33102.05124224826 29934.571319257462 27666.405996664118 38326.37475860686 27303.916981349874 1.4681083915664082 0.9317329322943234 1.335200752194486 1.2804787622306464 1.2052295018457055 1.2123554017857159 1.0963471409506729 1.0132760810678498 1.4036951102944661 1.0 14.73682031253364 -7.126834581344854 4.683686003591735 1.1299356286525826 1.2317568243460404 0.0990809514487273 0.16319053116751356 0.6372586040611813 21.491832549189798 0.06093500493610696 0.046886112546054334 7.467331278262302e-08 7.126834581344854 0.10182119569345782 LNSSSSSSSNSSNEREDFDSTS(ph)SSSSTPPLQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPR 33 1 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 LNSSS(0.001)S(0.001)S(0.007)S(0.006)S(0.006)NS(0.006)S(0.02)NEREDFDS(0.043)T(0.043)S(0.165)S(0.165)S(0.146)S(0.146)S(0.129)T(0.114)PPLQPR 48.07 0.0048043999999999995 15377000.0 7318.1 6128.1 11602.0 8883.8 11948.0 9682.5 12582.0 11058.0 9543.4 7316.8 True False 8556.90979093656 6736.457268798009 11878.635680830024 8386.069487668197 9606.875169435656 9174.732654932908 11390.141874208408 10767.739216919485 9682.954170661003 8643.277920243067 0.9900074797890939 0.7793868635209368 1.3743206906501941 0.9702417954220272 1.1114851631619744 1.061487636935189 1.3178034976212003 1.245793472832894 1.1202872636992216 1.0 13.077362835758398 -5.2455723692918585 24.990544941903973 1.1539667978235701 0.8846971653234331 0.3916777810536688 0.1322736045775711 792.3543772712995 1247953.336259337 0.03286279681372204 0.08632108663921052 5.681037168838943e-06 5.2455723692918585 -0.269269632500137 LNSSSSSSSNSSNEREDFDSTSSSS(ph)STPPLQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPR 33 1 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 LNSSSSSSSNSSNEREDFDS(0.069)T(0.069)S(0.069)S(0.069)S(0.069)S(0.217)S(0.217)T(0.217)PPLQPR 63.202 7.4779e-05 13849000.0 6872.9 6294.0 6816.5 7537.6 9550.3 9266.9 8154.7 5996.5 7191.3 5090.1 True False 8036.346224037365 6918.826724403104 6979.0312117202075 7115.292709228916 7678.98727240218 8780.927450554895 7382.227781084671 5839.098228816933 7296.459157897024 6012.894836790571 1.3365186723150517 1.1506648481642299 1.1606774109898317 1.1833389577501339 1.2770865749085507 1.460349413867644 1.2277327279891346 0.9710960173608486 1.213468613030253 1.0 12.5538440112374 -7.640689467337783 7.19163631299292 1.0705010334741663 1.2565537681908918 0.42328593110587487 0.10465925408836908 0.2398550691422683 14.066387835538215 0.052083370410431 0.029814046196379493 2.287233654652312e-08 7.640689467337783 0.18605273471672557 LNSSSSSSSNSSNEREDFDSTSSSSS(ph)TPPLQPR ddPTM_PC-9_AZD4547_30min_R2 2 LNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPR 33 1 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 LNSSSSSSSNSSNEREDFDS(0.07)T(0.07)S(0.07)S(0.07)S(0.07)S(0.07)S(0.291)T(0.291)PPLQPR;LNSSSSS(0.002)S(0.006)S(0.006)NS(0.005)S(0.005)NEREDFDS(0.07)T(0.07)S(0.07)S(0.07)S(0.07)S(0.07)S(0.279)T(0.279)PPLQPR 90.13600000000001 4.3727e-12 36297000.0 22763.0 24788.0 32462.0 53046.0 36962.0 28747.0 28940.0 39289.0 25364.0 31640.0 True False 30001.160500186885 32800.23624424029 32031.532669706005 40817.064252530276 31830.46431056161 26949.44554558865 31515.60393579131 33217.78782140345 26704.689258367736 30532.29323046646 0.9826042306658581 1.0742801399375654 1.0491034010423932 1.336848953481202 1.0425179684439745 0.8826538295753465 1.0322055961503624 1.0879558757891556 0.8746375208960926 1.0 14.898048331621919 -6.519847591590691 24.98509859675655 0.9820939749172035 1.1144537875181035 0.27186851610551144 0.10402032726727037 176.25570277005477 1452852.2879884096 0.0347269034757702 0.03537136389657779 3.0210117081013195e-07 6.519847591590691 0.13235981260090002 LNSSSSSSSNSSNEREDFDSTSSSSS(ph)TPPLQPR ddPTM_PC-9_Lapatinib_30min_R1 1 LNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPR 33 1 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 LNSSSSSSSNSSNEREDFDS(0.075)T(0.075)S(0.075)S(0.075)S(0.075)S(0.075)S(0.274)T(0.274)PPLQPR 60.641000000000005 0.00023334 18225000.0 14917.0 15061.0 17775.0 14788.0 14804.0 13093.0 12693.0 12656.0 16760.0 11080.0 True False 14704.280844557225 15026.127179845087 16313.608113484213 15875.55885132187 13933.25782578383 12533.042911273715 13350.181432674011 13244.043962999516 14872.312309375817 12995.163236828028 1.1315195181916293 1.1562861432368428 1.2553599994228453 1.221651360740961 1.07218798039391 0.9644390518893465 1.0273192563553084 1.0191517968367003 1.1444498263190712 1.0 13.665687135674544 -6.384714626724677 4.530637879456636 1.030919036026578 1.192670823590223 0.6679533423089863 0.05344918100537067 0.1431284505447587 4.653360947428126 0.017678119175453665 0.020101355053803397 4.123683958179306e-07 6.384714626724677 0.16175178756364494 LNTQEIFDDWAR ddPTM_PC-9_AZD4547_30min_R2 2 LNTQEIFDDWAR 12 0 Q14204 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ; 118.77 0.0024942 0.0 11688.3 12729.9 16573.699999999997 23221.2 19201.2 16452.2 16593.0 20407.2 14575.2 20883.7 False True 15404.936268257008 16844.59122823765 16353.9219089368 17867.91110396366 16535.444816837717 15423.441333187238 18069.74485509971 17253.736150804165 15345.615316139452 20152.568019503553 0.7644155451229933 0.8358533370008 0.8115056052960375 0.8866319710059376 0.8205130383797636 0.7653337936019127 0.8966472579381398 0.8561557084985937 0.7614719524225421 1.0 14.298676071054006 -11.208500214376512 2.970213680100253 1.0203061623554246 0.8255360393358682 0.56880811124059 0.04638948752348559 500912897.04081774 513091215.5136967 77156121.03357473 0.01143691337444459 6.187280221365333e-12 11.208500214376512 -0.19477012301955643 LNTQEIFDDWAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LNTQEIFDDWAR 12 0 Q14204 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 146.5 0.00057051 2005100.0 6475.5 6394.3 6796.8 7427.5 5489.7 6066.3 5695.5 6142.5 6179.3 5093.3 False True 7571.674253045142 7029.083845543494 6958.8614890075405 7011.3612552798995 4414.0326931411855 5748.172548889182 5155.981008150851 5981.2658835167185 6269.660572412927 6016.6749714593825 1.2584482773229455 1.1682671706360341 1.1565958809504422 1.165321591832515 0.7336332299948943 0.9553736201732909 0.8569485692028724 0.9941148411521928 1.0420474102645736 1.0 12.554750707288385 -6.128363234761624 8.303940390399319 0.9278830853656896 1.1866101477671451 0.6860594386661283 0.0852016526172911 0.17424190851649748 10.913761378112692 0.02540789424957384 0.032874479989831375 7.441093561700576e-07 6.128363234761624 0.2587270624014555 LNTQEIFDDWAR ddPTM_PC-9_Lapatinib_30min_R1 2 LNTQEIFDDWAR 12 0 Q14204 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ; 152.96 1.2829000000000002e-07 1346400.0 9985.3 8620.2 7909.9 6909.2 11343.1 8126.6 7948.6 6876.5 9639.9 6123.5 False True 9842.907790920242 8600.240456523507 7259.578555096982 7417.325616415542 10675.921159392641 7779.044262029859 8360.139615201506 7196.007293897452 8554.15294935274 7181.938815949133 1.3705084439123627 1.1974817214294156 1.0108104150059636 1.0327748267562067 1.486495698861194 1.0831398681306943 1.1640505202628446 1.0019588690893713 1.1910645813852232 1.0 12.81015764717416 -6.782010654006442 0.023188554330038143 1.0015749109164826e-06 2.311097999633642 0.16204483650347878 0.14411266699059952 948.1684097662775 8.76864764854571 408.9948306233889 462.81693823738505 1.651921273201651e-07 6.782010654006442 2.311096998058731 LNTS(ph)DFQK ddPTM_PC-9_AZD4547_30min_R2 4 LNTSDFQK 8 0 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 LNT(0.105)S(0.895)DFQK;LNT(0.086)S(0.914)DFQK;LNT(0.097)S(0.903)DFQK;LNT(0.076)S(0.924)DFQK 131.12 0.0033441000000000005 2749320000.0 1424460.0 1149000.0 1530310.0 1897500.0 1859280.0 1635500.0 1683290.0 1583390.0 1466100.0 1685030.0 True False 1877408.6493913925 1520391.780080366 1510017.0895132073 1460060.691082763 1601151.0655089316 1533231.9264552884 1833099.5490351832 1338713.4581824914 1543595.0528975292 1626037.6125832128 1.1545911575863474 0.9350286661973262 0.9286483152836245 0.8979255336924404 0.984694974530912 0.9429252525219954 1.1273414187037287 0.8232979654484975 0.9492984915922635 1.0 20.632929198729535 -4.758472243494114 24.990833178853368 0.9522598453555916 1.1545914333299743 0.39802212386306646 0.07383659643746747 83.6891627259557 704748.3649087973 0.018055253681162217 0.12341623468432035 1.7439248111326545e-05 4.758472243494114 0.20233158797438267 LNTS(ph)DFQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LNTSDFQK 8 0 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 LNT(0.29)S(0.71)DFQK;LNT(0.099)S(0.901)DFQK;LNT(0.086)S(0.914)DFQK;LNT(0.092)S(0.908)DFQK 123.67 0.0032816000000000004 1527370000.0 369718.0 465130.0 623470.0 1280700.0 2140690.0 2495560.0 3028250.0 3462000.0 2826700.0 2410070.0 True False 432303.9551366448 511305.0324629188 638335.8893231405 1208946.5310854232 1721237.1615717416 2364688.4404177 2741392.2373685883 3371126.1682922156 2868035.1399089964 2846996.612896378 0.15184561624639326 0.17959453486765659 0.22421378600578404 0.424639258652123 0.6045799822082153 0.830590535199828 0.9629067435312634 1.1840991144919617 1.00738972674478 1.0 21.441009346014994 -6.498571135308757 0.9157748480512163 1.0844369844724047 0.14239024854146723 0.9755595248784767 0.05784605096014783 0.07654389183350371 0.1400819916637566 0.03112882110663392 0.0382243008947167 3.172698948727481e-07 6.498571135308757 -0.9420467359309375 down LNTS(ph)DFQK ddPTM_PC-9_Lapatinib_30min_R1 3 LNTSDFQK 8 0 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 LNT(0.09)S(0.91)DFQK;LNT(0.091)S(0.909)DFQK;LNT(0.086)S(0.914)DFQK 131.12 0.0034460999999999997 1839040000.0 390690.0 318735.0 370740.0 576460.0 1046690.0 1034170.0 1083990.0 987360.0 1162890.0 925970.0 True False 385118.6889562281 317996.9886905203 340259.18829778564 618854.7914141867 985125.7520717165 989940.9598680169 1140113.6981961962 1033236.3501348934 1031913.0824254211 1086022.6807225302 0.3546138545651817 0.2928087915060458 0.31330762638530846 0.5698359734093794 0.9070950078283014 0.911528808228397 1.0498065265429626 0.9513948175073856 0.9501763644005021 1.0 20.05062280232302 -6.112102039202825 1.9383592385156567 0.9751963702593046 0.3085042303620739 0.982810330081007 0.03863437285175453 0.03860274352089793 0.2869789322171296 0.013006343501230162 0.019052520956881692 7.724990620678229e-07 6.112102039202825 -0.6666921398972308 down LNVSDENTASCPLS(ph)PIK ddPTM_PC-9_Lapatinib_30min_R1 1 LNVSDENTASCPLSPIK 17 0 Q8N3X6-3 Q8N3X6-3 1 LNVSDENTASCPLS(1)PIK 100.69 0.0011351 3561600.0 18620.0 15546.0 17875.0 18579.0 18684.0 18973.0 21321.0 18047.0 21173.0 17090.0 True False 18354.4753855102 15510.004192143386 16405.386499495376 19945.361637727125 17585.04385415734 18161.56901822318 22424.89705554577 18885.52950381259 18788.273778425686 20043.983729006413 0.9157099523558652 0.7737984824692442 0.8184693582520982 0.995079716057813 0.8773227963016829 0.9060857992985137 1.1187844372021638 0.9422043920581826 0.9373522764956379 1.0 14.290881651301495 -6.171128720056613 0.9386750939209858 0.986770433958559 0.8306896941775884 0.36726924012821704 0.0734844672635317 0.6440332439979636 1.19089974256498 0.035314290869965466 0.06294582381640246 6.74328134713378e-07 6.171128720056613 -0.1560807397809706 LNYSDES(ph)PEAGK ddPTM_PC-9_AZD4547_30min_R2 1 LNYSDESPEAGK 12 0 Q9GZR1-2;Q9GZR1 Q9GZR1-2 SENP6 Sentrin-specific protease 6 1 LNYS(0.001)DES(0.999)PEAGK 101.2 0.002794 7102500.0 49417.0 43112.0 48426.0 53742.0 53708.0 55127.0 52566.0 57561.0 53110.0 59432.0 True False 65130.57806254602 57047.11089889012 47783.83959901372 41352.61220562309 46251.57126756246 51679.89997535973 57244.27216616471 48666.270070192804 55917.28617378606 57351.30376969293 1.1356425012427358 0.9946959728757978 0.8331779132851187 0.7210404905821114 0.80646067704574 0.9011111618820734 0.9981337546578185 0.8485643197515294 0.9749959024180951 1.0 15.807538663012703 -10.054337014972438 18.56045014097489 0.9999999999999978 0.904254481508919 0.04684605526000418 0.11261966674797143 0.0 0.0 0.11764141508776743 0.028532234138470374 8.823948912448487e-11 10.054337014972438 -0.09574551849107882 LNYSDES(ph)PEAGK ddPTM_PC-9_Lapatinib_30min_R1 2 LNYSDESPEAGK 12 0 Q9GZR1-2;Q9GZR1 Q9GZR1-2 SENP6 Sentrin-specific protease 6 1 LNYS(0.007)DES(0.993)PEAGK;LNYS(0.025)DES(0.975)PEAGK 128.71 0.00019685 18778800.0 69448.0 79389.0 88103.0 81952.0 86208.0 89173.0 76709.0 81205.0 83417.0 81398.0 True False 68457.65878479663 79205.17964814571 80859.51142741485 87979.0234638577 81137.41493144908 85359.2786624159 80680.61667998029 84978.08075342732 74021.69904004797 95467.53584398278 0.7170778860017203 0.8296556410294939 0.846984377595741 0.9215595928613561 0.8498953514841672 0.8941183817912066 0.8451104971624289 0.8901254232884173 0.7753598999456471 1.0 16.54272260129089 -12.86613961902089 0.018883679314788696 1.9686256954060326 2.6741639721826808e-06 0.392411005704274 0.05747848084153814 3244.743422616784 6.184539676297733 398.07285506931646 259.5583082311574 1.3610070692097903e-13 12.86613961902089 -1.9686230212420603 LPACVVDCGTGYTK ddPTM_PC-9_Lapatinib_30min_R1 1 LPACVVDCGTGYTK 14 0 P61158;F8WEW2;F8WE84 P61158 ACTR3 Actin-related protein 3 0 87.001 0.028938 3843000.0 10228.0 9538.2 9963.0 7318.8 7904.3 7879.4 10203.0 10122.0 9954.7 8203.6 False True 10082.14684441452 9516.114883925267 9143.880598292164 7857.048966801084 7439.384614451717 7542.416429778511 10731.261416337582 10592.305072177716 8833.49685836178 9621.581329390114 1.0478679646574893 0.9890385538661209 0.9503511205960746 0.8166068235375111 0.7731977062572187 0.7839061139294662 1.1153324021237379 1.1008902496954869 0.9180920012990953 1.0 13.232058308447852 -9.771075399615608 9.364319854881476 0.9999927568331807 0.9416226992579381 0.019686680115276523 0.11771910679885962 0.0 0.0 0.1279388953262484 0.03102973994440964 1.6940436651658037e-10 9.771075399615608 -0.058370057575242607 LPALGEAHVS(ph)PEVATADK ddPTM_PC-9_AZD4547_30min_R2 2 LPALGEAHVSPEVATADK 18 0 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 LPALGEAHVS(0.974)PEVAT(0.026)ADK;LPALGEAHVS(0.596)PEVAT(0.404)ADK 94.234 0.00055003 7427500.0 30217.0 41082.0 33773.0 21259.9 26601.0 40249.0 41240.0 44328.0 34515.0 25503.0 True False 39825.37744735524 54360.95309770373 33325.14795311382 16358.758517180724 22907.91031668333 37732.22366731823 44910.28010753401 37478.12615610408 36339.39243623098 24610.14773250904 1.6182502388942377 2.2088836559845206 1.354122222886643 0.6647159820000367 0.9308318895795524 1.533197771806767 1.8248683671333386 1.5228728638063778 1.4766019623778228 1.0 14.586965697740421 LPALGEAHVS(ph)PEVATADK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LPALGEAHVSPEVATADK 18 0 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 LPALGEAHVS(0.981)PEVAT(0.019)ADK;LPALGEAHVS(0.963)PEVAT(0.037)ADK 111.45 0.00011431 7104000.0 33264.0 65753.0 40083.0 33108.0 37598.0 23125.0 39557.0 25508.0 25974.0 25347.0 True False 38894.938206052604 72280.52329356181 41038.73073562402 31253.066097584247 30230.941799501306 21912.284290764128 35809.87459212067 24838.44202796004 26353.820612019696 29942.210453258405 1.2990002280148938 2.4140009104002544 1.370597898898879 1.043779521434203 1.0096429536053668 0.7318191930074943 1.1959662980801649 0.8295460372484639 0.8801561478956137 1.0 14.86989311037258 -5.562055160554332 3.5746017576412936 0.9535193324668908 1.87083038764287 0.6211547900336827 0.2798347420924382 0.12627511698359398 3.368374997495727 0.0720292474186439 0.14122522096034856 2.741225981577841e-06 5.562055160554332 0.9173110551759792 LPALGEAHVS(ph)PEVATADK ddPTM_PC-9_Lapatinib_30min_R1 3 LPALGEAHVSPEVATADK 18 0 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 LPALGEAHVS(0.999)PEVAT(0.001)ADK;LPALGEAHVS(0.989)PEVAT(0.011)ADK;LPALGEAHVS(1)PEVATADK 89.831 0.00079375 10847100.0 27633.9 70119.0 62608.0 64341.0 83855.0 70620.0 94676.0 101831.0 72817.0 74342.0 True False 27239.8355185634 69956.64376359853 57460.61191386891 69072.85177528398 78922.81376527311 67599.74722326049 99577.86002677426 106562.44001234241 64615.5826629963 87191.91564551184 0.31241239875162163 0.8023294733885058 0.659013068912045 0.7921933044355527 0.9051620575254058 0.7752983372689571 1.1420538164526493 1.2221596374322539 0.7410730935847073 1.0 16.411906755390923 -4.696493490602927 0.4630432722857277 1.026737391761469 8.903154352545193e-14 0.5790002928879214 0.15836037695258517 3.979516242474136 0.6245772670259888 0.11058323667813522 2.289312502423094 2.0114373462842846e-05 4.696493490602927 -1.02673739176138 LPDDQIPK ddPTM_PC-9_Lapatinib_30min_R1 2 LPDDQIPK 8 0 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 0 ; 103.83 0.017821 6699800.0 60744.0 50494.0 53058.0 52225.0 53976.0 43952.0 56868.0 56433.0 49498.0 57934.0 False True 59877.779420914696 50377.08424534212 48695.77604980286 56065.80071749286 50801.23780089894 42072.27541711618 59812.34678273895 59055.08319879521 43923.01400295253 67947.81470779728 0.8812318641653605 0.7414084538551193 0.7166643439412161 0.8251302997542772 0.747650796708688 0.6191851143122667 0.8802688804629833 0.8691240984387156 0.6464227612299088 1.0 16.052139532294568 -10.834383856167168 3.9587581108551784 1.0004303718661427 0.770020347816939 0.37499060123085914 0.08920478242390746 65445464.42317313 248527.12234608678 257909.9493565221 0.02136501635387174 1.4642530719424435e-11 10.834383856167168 -0.23041002404920374 LPDGYEFK ddPTM_PC-9_AZD4547_30min_R2 1 LPDGYEFK 8 0 P09382 P09382 LGALS1 Galectin-1 0 92.439 0.036739 7327500.0 34803.0 30343.0 54368.0 58862.0 42167.0 51712.0 40178.0 39185.0 41609.0 48475.0 False True 45869.63005262945 40150.78136029464 53647.044796579845 45292.275308834534 36312.83990540156 48478.4404652131 43753.76416490063 33129.8586317212 43808.3667935429 46777.905004641696 0.9805832486101693 0.8583279083642276 1.1468458194366877 0.9682407817182119 0.7762818771340507 1.0363533907814524 0.9353510842471252 0.7082373318863635 0.9365183581692225 1.0 15.513539630143283 -6.019270125203579 24.543626420340804 0.8910313840092565 0.9942237792057916 0.1344167189820329 0.11205101487368305 1148.818157460432 1463207.29151265 0.033024965738415096 0.04335155200032081 9.565988948426206e-07 6.019270125203579 0.10319239519653511 LPDGYEFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LPDGYEFK 8 0 P09382 P09382 LGALS1 Galectin-1 0 103.74 0.017877 4644100.0 47057.0 40866.0 42333.0 53598.0 58306.0 47815.0 45718.0 50521.0 50986.0 39153.0 False True 55022.82068188482 44922.906406014816 43342.37926879655 50595.07782706051 46881.35785312314 45307.497226503176 41387.26007034336 49194.87728142422 51731.573793964584 46251.12896502255 1.189653569829525 0.9712823753986156 0.9371096498330722 1.0939209260237317 1.013626237936315 0.9795976496220665 0.8948378341562756 1.0636470586183502 1.11849321198379 1.0 15.497200961013226 -3.627361264380387 11.612298599141702 1.0205702019915999 1.0271488095520698 0.0 0.08530400300743841 0.0 0.0 0.019527034226514098 0.0 0.0002358515504753763 3.627361264380387 0.006578607560469907 LPDLS(ph)PVENK ddPTM_PC-9_AZD4547_30min_R2 5 LPDLSPVENK 10 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3;H7C5N8;A0A2R8Y7F4;A0A2R8YET2 E7EPN9 PRRC2C Protein PRRC2C 1 LPDLS(1)PVENK;LPDLS(1)PVENK;LPDLS(1)PVENK;LPDLS(1)PVENK;LPDLS(1)PVENK 117.2 0.00097676 42170800.0 175411.0 208676.0 206712.0 172076.0 188620.0 226523.0 227890.0 235255.0 228127.0 203509.0 True False 231188.049224543 276126.4361184077 203970.8638167785 132406.53674769812 162433.36881819533 212358.48100056942 248171.76851857212 198901.74537209535 240185.32748949932 196384.21185331824 1.1772231944858182 1.406052113418618 1.0386316796643857 0.6742219015375542 0.8271203030288341 1.0813419215144573 1.2637052957390211 1.0128194292963708 1.2230378665515977 1.0 17.583319424473906 -5.34172687808487 6.970579809452865 1.0067298077270133 1.2903534247298885 0.2979106006976773 0.1697216267640015 0.3076866195524988 22.729401152524503 0.049123552531275705 0.10341888062388177 4.5527428596848306e-06 5.34172687808487 0.2836236170028752 LPDLS(ph)PVENK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 LPDLSPVENK 10 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3;H7C5N8;A0A2R8Y7F4;A0A2R8YET2 E7EPN9 PRRC2C Protein PRRC2C 1 LPDLS(1)PVENK;LPDLS(1)PVENK;LPDLS(1)PVENK;LPDLS(1)PVENK;LPDLS(1)PVENK;LPDLS(1)PVENK;LPDLS(1)PVENK 142.19 0.00011955 39644400.0 154833.0 229996.0 193990.0 186432.0 186628.0 127702.2 177495.0 140875.0 121152.0 123908.5 True False 181043.16880885433 252828.48288938915 198615.45731117175 175986.81946069875 150059.583120308 121005.2718251252 160681.3886474825 137177.18051940078 122923.61880293401 146372.13019085402 1.2368691264709537 1.7272993332796833 1.3569212735525396 1.2023246449391032 1.025192315809341 0.8266961180885112 1.0977594466786176 0.9371810080275256 0.8398020760007688 1.0 17.15928135959534 -5.964778307471974 1.7881714221392424 0.9463106381078275 1.4888958511902606 0.7275490036471932 0.13480266080084435 0.16951572239254045 1.0959063383436496 0.04257506205507713 0.07211781304362114 1.0844803630064277e-06 5.964778307471974 0.5425852130824331 LPDLS(ph)PVENK ddPTM_PC-9_Lapatinib_30min_R1 4 LPDLSPVENK 10 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3;H7C5N8;A0A2R8Y7F4;A0A2R8YET2 E7EPN9 PRRC2C Protein PRRC2C 1 LPDLS(1)PVENK;LPDLS(1)PVENK;LPDLS(1)PVENK;LPDLS(1)PVENK 117.95 0.00091417 37477700.0 92052.0 210298.0 205697.0 182622.0 243673.0 232057.0 227654.0 230165.0 207046.0 197796.0 True False 90739.32159973067 209811.06790167015 188785.38667338164 196052.63108913333 229340.6332195506 222132.46306128806 239440.81020042294 240859.30615864258 183726.29918896322 231984.77505339685 0.39114343421392567 0.9044174034842464 0.813783519327629 0.8451099044926854 0.9886020889377863 0.9575303509041011 1.0321401917229693 1.0382547997091751 0.7919756766222017 1.0 17.82367060015295 -4.586250815278421 2.1509348307337084 0.9394082220097101 6.318811090491106e-21 0.7775618723388031 0.08608913497538649 0.687202165131615 2.192720279323774 0.023713942235330375 1.5163494679924268 2.5926815950584926e-05 4.586250815278421 -0.9394082220097101 down LPDS(ph)DDDEDEETAIQR ddPTM_PC-9_AZD4547_30min_R2 1 LPDSDDDEDEETAIQR 16 0 H3BRF9;Q96K21-3;Q96K21-2;Q96K21;H3BRM1;Q96K21-4 H3BRF9 ZFYVE19 Abscission/NoCut checkpoint regulator 1 LPDS(1)DDDEDEETAIQR 140.77 2.1923000000000003e-05 5104200.0 1104.9 1085.1 1094.0 3439.6 1498.0 1027.4 1157.3 1577.3 0.0 1038.2 True False 1456.2352166523085 1435.8373547129731 1079.492845193099 2646.653361290258 1290.0285573621904 963.1565155855495 1260.2974580128293 1333.564527748216 0.0 1001.8529340034856 1.4535418994413425 1.4331817634902266 1.0774963156312354 2.6417583574008376 1.2876426405292158 0.9613751508783809 1.2579665290558948 1.3310980908337353 0.0 1.0 9.96845502976623 -7.548379695856999 0.9853723545627694 0.6477793742004675 1.5673944956440953 0.3200881478761841 0.5054662016629289 0.7042643729376155 1.258971467883986 0.42484296545591177 0.1964120273805941 2.828917642484236e-08 7.548379695856999 0.9196151214436278 LPDS(ph)DDDEDEETAIQR ddPTM_PC-9_Lapatinib_30min_R1 2 LPDSDDDEDEETAIQR 16 0 H3BRF9;Q96K21-3;Q96K21-2;Q96K21;H3BRM1;Q96K21-4 H3BRF9 ZFYVE19 Abscission/NoCut checkpoint regulator 1 LPDS(0.994)DDDEDEET(0.006)AIQR;LPDS(1)DDDEDEETAIQR 163.9 7.992799999999999e-06 13275100.0 5386.6 6471.1 6581.79 4459.93 5315.4 5724.9 5889.200000000001 5520.8 6788.6900000000005 3940.79 True False 5309.786096218543 6456.116565533198 6040.660632644122 4787.928130090337 5002.758622478475 5480.059372393711 6194.113959923089 5777.316522671283 6024.07624412509 4621.950300727395 1.1488193837529792 1.3968381625646524 1.3069505813797808 1.0359107776076304 1.0823912627730223 1.1856595194308488 1.3401515717181705 1.2499737441491003 1.3033624016201624 1.0 12.17428603142574 -11.728340409881639 2.365726496630148 0.30199373925491796 1.2278837592267888 0.2807338309167863 0.10938097010369142 4469647.561475021 950464.0934788734 16784547.528344594 0.030400582001904326 1.8692164317071253e-12 11.728340409881639 0.9258900199718709 LPDS(ph)PALAK ddPTM_PC-9_AZD4547_30min_R2 1 LPDSPALAK 9 0 H0YDB2;E9PNJ4;G0XQ39;Q13586 H0YDB2 STIM1 Stromal interaction molecule 1 1 LPDS(1)PALAK 88.596 0.0099959 8469400.0 23828.0 32385.0 45665.0 33571.0 47218.0 36129.0 48464.0 57931.0 47061.0 33412.0 True False 31404.808346810743 42852.81792680824 45059.452263019055 25831.72461677964 40662.59574200798 33869.84791862012 52777.20211279165 48979.095071946926 49548.54838306431 32242.256049821288 0.9740263925168107 1.3290886921991851 1.3975278961060422 0.8011760894418807 1.2611585144406594 1.0504800863278256 1.6368954464985146 1.5190963993420183 1.5367581073266414 1.0 14.976665074966652 -7.253212867931146 24.943336368618006 1.4664455245733314 1.1467874593916472 0.26711620642666944 0.2284938920594646 720.4386663498778 2184423.097759559 0.08561782847208121 0.06514707138462462 5.581965295850362e-08 7.253212867931146 -0.31965806518168427 LPDS(ph)PALAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LPDSPALAK 9 0 H0YDB2;E9PNJ4;G0XQ39;Q13586 H0YDB2 STIM1 Stromal interaction molecule 1 1 LPDS(1)PALAK;LPDS(1)PALAK;LPDS(1)PALAK 103.08 0.0029698 12767400.0 109504.0 159860.0 136279.0 97158.0 168373.0 95675.0 124657.0 75016.0 77346.0 81267.0 True False 128040.86439741382 175729.8443220656 139528.40820098546 91714.55225048591 135381.5193256938 90657.63457378838 112848.58652147475 73046.90948602218 78477.03892574391 96000.06379078206 1.3337581178743791 1.8305179953321988 1.4534199529811458 0.9553592844517709 1.4102232225672038 0.9443497326352125 1.1755053284903179 0.7609048015344773 0.8174686122789773 1.0 16.550747744035476 -6.078424766582489 0.6118758488743482 0.87778668073133 1.6683273709876119 0.5652184265175886 0.21045028686722544 0.7612477754015395 0.5551630041318278 0.13960791817595425 0.34778353004102797 8.34786146880016e-07 6.078424766582489 0.7905406902562818 LPDS(ph)PALAK ddPTM_PC-9_Lapatinib_30min_R1 2 LPDSPALAK 9 0 H0YDB2;E9PNJ4;G0XQ39;Q13586 H0YDB2 STIM1 Stromal interaction molecule 1 1 LPDS(1)PALAK;LPDS(1)PALAK 93.561 0.0061611999999999995 11091100.0 71724.0 223996.0 81831.0 62820.0 80612.0 78766.0 94284.0 80551.0 108695.0 33421.0 True False 70701.20260742943 223477.35102427367 75103.17105679482 67439.99236137683 75870.56064928984 75397.36179251398 99165.56418484496 84293.69352588305 96452.62449090715 39197.77531931673 1.8037044712735968 5.701276391421725 1.9160059581183386 1.7205056106370988 1.9355833342894002 1.923511249766209 2.5298773559726997 2.150471368316226 2.4606657828199534 1.0 15.258484155653539 LPDSSNKIEEDRCS(ph)NSADITGPSFIR ddPTM_PC-9_AZD4547_30min_R2 1 LPDSSNKIEEDRCSNSADITGPSFIR 26 2 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 LPDS(0.001)S(0.001)NKIEEDRCS(0.976)NS(0.022)ADITGPSFIR 51.232 0.0056159 27306000.0 28128.0 22664.0 27970.0 34301.0 31854.0 25192.0 23408.0 27240.0 22694.0 26596.0 True False 37072.11890125452 29989.69478132411 27599.09952472665 26393.434395167216 27431.621940063585 23616.74025757363 25491.266652695347 23030.683912928052 23893.558509280763 25664.88213519235 1.444468698744588 1.1685109100969322 1.0753643589456447 1.0283871266634752 1.0688388045409583 0.9201967160094511 0.9932352900908539 0.8973617642820881 0.9309825926111422 1.0 14.647508014601577 -1.5228787452869361 0.5596182501267581 0.95043378550002 24.175387357743674 0.9187177279287329 0.04333861533072372 35.487252245349424 0.31516023660812875 0.02114226360242702 994.298729885774 0.029999999999544186 1.5228787452869361 23.224953572243653 LPDSSNKIEEDRCS(ph)NSADITGPSFIR ddPTM_PC-9_Lapatinib_30min_R1 1 LPDSSNKIEEDRCSNSADITGPSFIR 26 2 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 LPDS(0.001)SNKIEEDRCS(0.959)NS(0.038)ADIT(0.001)GPSFIR 52.653999999999996 0.00374 25722000.0 42581.0 50697.0 75895.0 64201.0 68222.0 56014.0 50871.0 31819.0 63555.0 44170.0 True False 41973.78713160094 50579.61421131438 69655.2060631723 68922.55570825779 64209.31608961259 53618.411795011496 53504.85146628535 33297.42690097042 56396.76663618024 51804.725647174535 0.8102308545647171 0.9763513575150653 1.3445724341360612 1.330429895096199 1.239449013337543 1.035010052175344 1.0328179678180294 0.6427488319839503 1.0886413533058863 1.0 15.660796086665508 -7.265636989099123 2.5051969193380383 0.8981185994205334 1.1486273812404963 0.1927142045200163 0.18730565202465124 0.44443281715151706 5.503547014559146 0.09338835024581592 0.06188863114406228 5.424541185489329e-08 7.265636989099123 0.25050878181996294 LPEAS(ph)QSPLVLK ddPTM_PC-9_AZD4547_30min_R2 1 LPEASQSPLVLK 12 0 H0Y4T7;E7ESY4;Q13330-3;Q13330;F8W9Y9 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 LPEAS(0.633)QS(0.367)PLVLK 73.877 0.021618000000000002 11217000.0 32477.0 36202.0 53146.0 60161.0 53932.0 50539.0 32425.0 43837.0 37585.0 50977.0 True False 42804.01043643498 47903.588531304966 52441.24931502046 46291.81092818448 46444.472734083916 47378.78834064439 35310.762184451756 37062.99892404652 39571.66636870172 49192.31074619121 0.8701362019215402 0.9738023647326626 1.0660456587533003 0.9410375366798295 0.9441409039253142 0.9631340268827027 0.7178106018771592 0.753430736670897 0.804427882497177 1.0 15.586145204965872 -7.242018179652519 24.00237394369423 0.7983698749230775 0.9636325940647432 0.3974705600753542 0.08332159417568431 414.49726596352997 512271.5055760923 0.031048470857686878 0.024007596877760135 5.727720541330375e-08 7.242018179652519 0.16526271914166568 LPEAS(ph)QSPLVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LPEASQSPLVLK 12 0 H0Y4T7;E7ESY4;Q13330-3;Q13330;F8W9Y9 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 LPEAS(0.741)QS(0.259)PLVLK 123.1 0.00037051 6896700.0 19988.0 19724.0 18998.0 26160.0 25860.0 22782.0 20843.0 24307.0 20018.0 14688.0 True False 23371.573619004903 21682.06836862517 19450.98437031622 24694.34001186431 20792.91863756327 21587.271814581105 18868.600149747734 23668.96700539536 20310.72537966468 17350.81812985597 1.347001244787926 1.2496280121406098 1.1210413379209159 1.4232377878119862 1.1983826054740552 1.2441644914389005 1.0874761068055967 1.364141265746288 1.1705917973236968 1.0 14.082716070252605 -14.179437603999606 0.21178474162347918 2.141345736070731e-11 1.2788672788073903 0.37265756172980224 0.09966426564736315 139.04187155365105 1.579841626007875 59.15819403597236 0.20421498679166067 6.615495768738506e-15 14.179437603999606 1.2788672787859767 LPEASQS(ph)PLVLK ddPTM_PC-9_AZD4547_30min_R2 3 LPEASQSPLVLK 12 0 H0Y4T7;E7ESY4;Q13330-3;Q13330;F8W9Y9 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 LPEASQS(1)PLVLK;LPEAS(0.157)QS(0.843)PLVLK;LPEAS(0.123)QS(0.877)PLVLK 156.6 0.00037887 15714200.0 67116.0 58967.9 75007.0 114323.0 93329.0 87551.0 72626.0 88063.0 74900.0 90854.0 True False 88457.49190047629 78028.12049486599 74012.3581712969 87967.59862274284 80371.87932580504 82076.42212967738 79089.57330479543 74454.88683642383 78859.06108861939 87673.22911380527 1.008945293729891 0.8899879847425337 0.8441842386713542 1.0033575757607314 0.9167208752112618 0.9361628738817993 0.9020949051863058 0.8492317163290152 0.8994656850867835 1.0 16.419848764742014 -7.277404879951568 16.074654883080537 0.9001333688194096 0.9296511954183815 0.009002919198004111 0.05777210968239557 27.506195658410697 27684.135845293466 0.02369439808298003 0.016174494892367882 5.279528274064856e-08 7.277404879951568 0.02951782659897184 LPEASQS(ph)PLVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LPEASQSPLVLK 12 0 H0Y4T7;E7ESY4;Q13330-3;Q13330;F8W9Y9 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 LPEAS(0.045)QS(0.955)PLVLK;LPEAS(0.144)QS(0.856)PLVLK 104.55 0.0018972000000000001 13368400.0 51965.0 47691.0 54022.0 54974.0 69730.0 52458.0 59918.0 51574.0 49082.0 42545.0 True False 60761.648144466184 52425.44730116117 55310.08935957591 51893.98500811269 56066.90706099328 49707.010132968804 54242.13327124617 50220.23714716997 49799.73139597869 50258.07171396532 1.20899282587442 1.0431249252763033 1.1005215177049217 1.0325502598559266 1.115580147604705 0.9890353616403593 1.0792720735478156 0.9992471942216431 0.9908802645554093 1.0 15.617067698956099 -1.5228787452803376 0.35804343975716896 1.01166680266102 2.9234687946420883 0.5564663622100967 0.04481313480919093 50.15852806083481 0.7013792966600064 0.035381153573996994 65.23221432771068 0.029999999999999995 1.5228787452803376 1.9118019919810683 LPEASQS(ph)PLVLK ddPTM_PC-9_Lapatinib_30min_R1 2 LPEASQSPLVLK 12 0 H0Y4T7;E7ESY4;Q13330-3;Q13330;F8W9Y9 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 LPEAS(0.011)QS(0.989)PLVLK;LPEAS(0.039)QS(0.961)PLVLK 135.14 5.949e-05 10793000.0 49600.0 47268.0 55900.0 43250.0 49371.0 43951.0 49798.0 42285.0 57122.0 35205.0 True False 48892.694904474 47158.55385013724 51304.11778024007 46430.749277770556 46467.094847120636 42071.31818478507 52376.29677651468 44249.715468981885 50688.318838673375 41290.13734228617 1.1841252669896518 1.1421263499126484 1.2425271767671828 1.1244997538484758 1.125380002055179 1.0189193084058568 1.2684941283272246 1.0716776043189553 1.227613229243544 1.0 15.333509596869682 -11.816815423003787 2.4173519069457363 0.21302193138298128 1.1532268456608112 0.28762349704871193 0.07359473549060178 1417644.3297174624 1013245.7423637513 6403091.1049603745 0.017530337471598663 1.5247006203428864e-12 11.816815423003787 0.9402049142778299 LPEGPVDS(ph)EDDEEEDEEIDRTDPLQGR ddPTM_PC-9_Lapatinib_30min_R1 1 LPEGPVDSEDDEEEDEEIDRTDPLQGR 27 1 E9PCH4;Q8TEU7;Q8TEU7-4;B7Z7Y1;Q8TEU7-2;Q8TEU7-5;Q8TEU7-3;D6RD23;D6RIH0;D6RB02;Q8TEU7-6 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 1 LPEGPVDS(1)EDDEEEDEEIDRTDPLQGR 77.51 1.8844e-05 2133500.0 719.22 1921.1 2283.6 2026.8 3733.3 2139.4 1983.5 3059.4 3142.3 1586.3 True False 708.9637909112054 1916.6518109820327 2095.8512229509183 2175.8576332065973 3513.7146339502033 2047.9028491849836 2086.195924659963 3201.550892888806 2788.381084114059 1860.4898413881142 0.38106297338460415 1.0301866574837173 1.1265050613698597 1.1695079353850095 1.8885965167800194 1.1007331529727893 1.1213154075076537 1.720810735789949 1.4987349149047993 1.0 10.86146679777076 -4.7756128313127375 1.1457698808640546 1.385648586648976 2.8883881845909913e-15 0.529561535680529 0.2740437112686524 1.3296442918397966 1.4385478964029919 0.08601495920586012 2.2406011123843848 1.676436734701295e-05 4.7756128313127375 -1.3856485866489732 LPEPSVLSEVTKPPPCLENS(ph)SPPSR ddPTM_PC-9_AZD4547_30min_R2 1 LPEPSVLSEVTKPPPCLENSSPPSR 25 1 Q9BZL4-3;K7EL81;Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-3;Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 LPEPSVLSEVTKPPPCLENS(0.769)S(0.228)PPS(0.003)R 100.9 6.7214e-07 9278900.0 10786.0 18212.0 14456.0 13410.0 14676.0 20114.0 17006.0 22708.0 17313.0 17624.0 True False 14215.723637262914 24098.672844929177 14264.303994617392 10318.531682434694 12638.490726199949 18856.26840031898 18519.501055012686 19199.000377928416 18228.129834809977 17006.9891243281 0.8358753882500961 1.416986432387176 0.8387318819539102 0.6067230129332107 0.7431351095603914 1.1087364296214859 1.0889347267542477 1.1288888490241165 1.0718022867866166 1.0 14.053840131962648 -6.792840542426648 24.98222269110489 1.0883070228927822 0.8992664151913858 0.18624988204895532 0.19894992664834382 394.7362368276193 314042.5970914364 0.07704947742166492 0.0679575446842693 1.6112371158679223e-07 6.792840542426648 -0.1890406077013964 LPFPIIDDR ddPTM_PC-9_AZD4547_30min_R2 1 LPFPIIDDR 9 0 P30041 P30041 PRDX6 Peroxiredoxin-6 0 131.03 0.005744399999999999 6345600.0 5825.2 6177.6 8833.6 9483.6 6122.1 7406.9 6642.0 8076.7 7656.9 5500.2 False True 7677.49242831299 8174.388390447754 8716.460692228293 7297.302540159411 5272.152090138231 6943.745372095195 7233.125132741046 6828.631599102279 8061.628102128841 5307.639672130584 1.4464984253972735 1.5401174336249555 1.6422480105416324 1.3748677361193475 0.9933138675221885 1.3082548554596678 1.3627762206091012 1.2865665382219027 1.5188725309404352 1.0 12.373854716245175 -5.982201229335263 9.286539561518216 1.2607166071462612 1.537520176624738 0.4255503370679904 0.15451001555770208 0.2421841227879032 112.78336407264149 0.04382301688379229 0.06424377533355165 1.0418345859142835e-06 5.982201229335263 0.27680356947847673 LPFPIIDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LPFPIIDDR 9 0 P30041 P30041 PRDX6 Peroxiredoxin-6 0 ; 167.9 0.0062701 8865800.0 14869.5 17243.300000000003 15894.7 16931.800000000003 15279.8 12862.8 16558.8 11773.8 12357.099999999999 14112.2 False True 17386.612663988068 18955.100867000332 16273.689928985432 15983.166139636254 12285.832876962077 12188.25212433473 14990.230588669705 11464.750225372276 12537.799210163566 16670.630147886262 1.0429487373752688 1.137035654852179 0.9761892492737498 0.9587619662753315 0.7369747134915502 0.7311212603370082 0.8991999975819976 0.6877214672551498 0.7520890991486177 1.0 14.025021018609722 -5.904449504842346 1.8896787352281343 0.7876626923897843 1.0787154547587268 0.5926622936569924 0.0940838666591469 0.21105420701683333 1.5326834353205074 0.028795482353350266 0.05061715671819895 1.2460931113433866e-06 5.904449504842346 0.2910527623689425 LPFPIIDDR ddPTM_PC-9_Lapatinib_30min_R1 2 LPFPIIDDR 9 0 P30041 P30041 PRDX6 Peroxiredoxin-6 0 ; 162.25 0.00032952 17515900.0 17248.7 23076.0 23125.0 22557.5 23587.0 24336.0 25639.0 20818.8 22347.0 20165.9 False True 17002.73037497581 23022.56893978522 21223.751765081444 24216.453799614068 22199.659033826214 23295.206009986807 26966.461967409516 21786.117450765978 19830.0455356576 23651.54894562728 0.7188844339143923 0.9734063926515752 0.8973514510137531 1.0238844760351828 0.9386133265462305 0.9849336321921379 1.1401562759970991 0.9211285696700137 0.8384248144273779 1.0 14.529647048653207 -4.761054167219607 24.983437861071682 0.9706176583669789 0.7188841489186923 0.48757126588251276 0.07679392988215859 8.169998045666883 529201.9025682308 0.019616776488068827 0.11181685104833793 1.733587763173042e-05 4.761054167219607 -0.25173350944828654 LPGPPPAS(ph)PIPTEGPR ddPTM_PC-9_AZD4547_30min_R2 2 LPGPPPASPIPTEGPR 16 0 Q9H6A9;Q9H6A9-3 Q9H6A9 PCNXL3 Pecanex-like protein 3 1 LPGPPPAS(0.986)PIPT(0.014)EGPR;LPGPPPAS(0.992)PIPT(0.008)EGPR 124.46 3.5279e-05 13496400.0 13185.3 14057.3 10528.4 17498.0 12113.2 12744.6 15298.300000000001 18558.5 14964.5 10504.9 True False 17377.951128722667 18601.04731951586 10388.786536865646 13464.106441405094 10431.49126905187 11947.678147295686 16659.819063265946 15690.71025690438 15755.492919367756 10137.126648442714 1.714287660733952 1.8349427766470088 1.024825564200837 1.3281975167463729 1.0290382699967922 1.178605985861991 1.6434458837332628 1.5478459331781969 1.5542365668074343 1.0 13.307361160343758 -5.243232584935522 24.95231782375832 1.3087757376109277 1.7746153125754491 0.4246293655948682 0.22544027273930892 846.988140126406 1160788.5332875447 0.06133283732104295 0.1615772583768358 5.711726651662591e-06 5.243232584935522 0.46583957496452144 LPIGDVATQYFADR ddPTM_PC-9_Lapatinib_30min_R1 1 LPIGDVATQYFADR 14 0 Q99832-3;Q99832;Q99832-2;Q99832-4 Q99832-3 CCT7 T-complex protein 1 subunit eta 0 110.8 0.0021203000000000003 5210800.0 2453.2 2629.6 5610.6 2463.2 2217.7 0.0 1930.4 2587.0 2465.8 2044.2 False True 2418.2169181382174 2623.5113227621414 5149.318125542311 2644.3519449943224 2087.2592461659556 0.0 2030.346666480258 2707.201464307818 2188.075637974874 2397.5372462747173 1.0086253808551389 1.0942525822439428 2.147753130235327 1.1029450946395534 0.8705847007837437 0.0 0.8468467672963169 1.1291592939856328 0.9126346801805463 1.0 11.227337512668134 -6.116871487258511 3.924369419609217 0.7649382012747321 1.412847073530086 0.31683873646244143 0.4049299134038231 0.2878841356200083 7.724561066709109 0.12941206358119156 0.17277038500406938 7.640618448330041e-07 6.116871487258511 0.6479088722553539 LPIPS(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 1 LPIPSPQR 8 0 P54198 P54198 HIRA Protein HIRA 1 LPIPS(1)PQR 60.167 0.040163 28884000.0 1505.7 0.0 175670.0 347370.0 222340.0 55195.0 18677.0 231440.0 25633.0 48882.0 True False 1984.4812794944146 0.0 173340.5010192611 267289.21331300074 191471.92886776367 51743.647924610035 20339.216817856748 195676.26596211657 26987.908049193324 47170.65605852284 0.042070249712710034 0.0 3.674752812515563 5.666429845312839 4.05913219926837 1.096945691414884 0.4311836747113005 4.148262549483061 0.5721334046257582 1.0 15.52560204583556 -5.2485472868128715 24.05331915351928 2.7267312050318635 0.02103416523547962 0.2631549147228066 1.699621570302239 634.6560519060693 1184094.7315146106 0.46105857015183904 1.2012189403792872 5.6422550404967456e-06 5.2485472868128715 -2.7056970397963838 LPIPS(ph)PQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LPIPSPQR 8 0 P54198 P54198 HIRA Protein HIRA 1 LPIPS(1)PQR;LPIPS(1)PQR 63.426 0.036987 5351100.0 8437.8 0.0 328610.0 25067.4 121266.0 67085.0 11015.8 25456.8 48270.0 9327.0 True False 9866.15288585349 0.0 336445.3086603641 23662.954847607332 97504.79781526464 63566.944503607025 9972.303676514466 24788.58597370914 48975.857432131816 11017.91126750863 0.8954649067603557 0.0 30.536215122055626 2.147680651357977 8.849662649108666 5.769418809086196 0.9050992909992279 2.2498444007994207 4.445112711749605 1.0 13.427563128901019 -6.954430251249551 2.261383370946075 2.2310734082388852 9.01831059239508 0.11513737750169784 8.16549689588452 0.7135494465158879 7.380998350696471 3.513821344650776 2.8566936135909264 1.1106308910343844e-07 6.954430251249551 6.787237184156195 LPLLPPES(ph)PGPLR ddPTM_PC-9_AZD4547_30min_R2 5 LPLLPPESPGPLR 13 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;A0A669KAX5 A0A0G2JMS7 SCRIB Protein scribble homolog 1 LPLLPPES(1)PGPLR;LPLLPPES(1)PGPLR;LPLLPPES(1)PGPLR;LPLLPPES(1)PGPLR;LPLLPPES(1)PGPLR 198.37 6.974800000000001e-07 43802690.0 52597.15 93048.7 95453.2 109518.5 105954.4 78633.6 86915.5 131078.9 83008.5 81587.2 True False 69321.94961131676 123124.87260849786 94187.42819998716 84270.70186895778 91244.46046607231 73716.62856136655 94650.81112236588 110823.66789846926 87396.15984478862 78730.85696121078 0.8804927608684658 1.5638706011946393 1.1963216435760573 1.07036434152465 1.1589415381446533 0.9363117766860503 1.2022073018841717 1.4076268463973407 1.11006234681082 1.0 16.264641561152253 -5.520434916801689 24.975862551860892 1.1395506002225957 1.2616602702211752 0.030805701279804865 0.1947365357939063 269.7135188298873 2756462.367517638 0.05155380774327136 0.09136335037611644 3.0169289550601457e-06 5.520434916801689 0.12210966999857953 LPLLPPES(ph)PGPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LPLLPPESPGPLR 13 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;A0A669KAX5 A0A0G2JMS7 SCRIB Protein scribble homolog 1 LPLLPPES(1)PGPLR;LPLLPPES(1)PGPLR;LPLLPPES(1)PGPLR 118.73 0.00023881 89697000.0 11026.400000000001 9953.5 18974.5 15878.7 28811.6 14701.900000000001 13613.8 16961.4 15766.900000000001 15300.3 True False 12892.951738672986 10941.617699610151 19426.92404119196 14989.067918439981 23166.173805801154 13930.906482784208 12324.202308623311 16516.18122208882 15997.461084455737 18074.123272891844 0.7133376011665392 0.6053747412479334 1.0748473797525266 0.8293109265731894 1.281731537183136 0.7707652688016261 0.6818699929477381 0.9138026211683709 0.8851030195444803 1.0 14.1416380471669 -5.247256497598151 24.59708048762955 0.9210633089944136 0.6593561330344457 0.3129689619775661 0.15979907439725183 819.8497093810648 1421841.07666416 0.04167746535413204 0.1090400285322083 5.659049625789499e-06 5.247256497598151 -0.26170717595996784 LPLLPPES(ph)PGPLR ddPTM_PC-9_Lapatinib_30min_R1 4 LPLLPPESPGPLR 13 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;A0A669KAX5 A0A0G2JMS7 SCRIB Protein scribble homolog 1 LPLLPPES(1)PGPLR;LPLLPPES(1)PGPLR;LPLLPPES(1)PGPLR;LPLLPPES(1)PGPLR 145.81 9.225700000000001e-05 98662600.0 73818.0 75885.0 38613.5 27318.7 40375.4 31295.199999999997 33734.700000000004 33775.5 58015.0 25026.3 True False 72765.34178343657 75709.29294486051 35438.84708242042 29327.808330511663 38000.59835309054 29956.777248674352 35481.3177008452 35344.8330335248 51480.73977496647 29352.062609551376 2.479053780696086 2.5793517120743723 1.207371609751485 0.9991736771837009 1.294648313428061 1.020602117376453 1.2088185478760636 1.2041686304533616 1.7539053544473653 1.0 14.84117426659908 -5.262770565591607 24.98603194157151 1.206909827661088 2.5292028514667364 0.8653269089441226 0.20799517781155563 34.5585634336002 648670.8126494901 0.05338607638298067 0.12194414195802587 5.4604625691082065e-06 5.262770565591607 1.3222930238056485 LPLPS(ph)PALEYTLGSR ddPTM_PC-9_AZD4547_30min_R2 2 LPLPSPALEYTLGSR 15 0 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 LPLPS(1)PALEYTLGSR;LPLPS(1)PALEYTLGSR 122.96 4.1928e-05 265180000.0 94629.0 113452.0 117811.0 165106.0 144046.0 148859.0 122464.0 165123.0 136412.0 168049.0 True False 124719.05359452544 150123.14032521975 116248.74916366008 127043.36256227175 124047.69931494929 139550.82319792616 133363.05875579664 139607.03449906094 143622.45982938266 162165.65566013486 0.7690842619346625 0.9257394219146273 0.716851843199728 0.7834171917913861 0.7649443330647471 0.8605448707980151 0.8223878120981275 0.8608914996875044 0.8856527557868674 1.0 17.307108784403503 -8.605306173842113 0.6687760952238163 1.0010716243882847 0.7986299934884135 0.5676433327650593 0.05310314806611524 0.656084765073795 0.658656850596016 0.05384188806051072 0.021389709200039235 2.4813831349276713e-09 8.605306173842113 -0.20244163089987122 LPLPS(ph)PALEYTLGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LPLPSPALEYTLGSR 15 0 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 LPLPS(1)PALEYTLGSR;LPLPS(1)PALEYTLGSR 174.4 6.9404e-05 61132000.0 55344.0 77419.0 90673.0 63676.0 96792.0 64218.0 56507.0 70476.0 71330.0 69372.0 True False 64712.64610617406 85104.64667565368 92834.98819926758 60108.4401603774 77826.30242718567 60850.295030671994 51154.24788474762 68626.0796754945 72373.066306898 81948.59445155026 0.7896736550427786 1.0385125851788628 1.1328441789706787 0.7334895804212332 0.9496966110040878 0.7425422661354854 0.6242236151468235 0.8374283919667187 0.8831520148852156 1.0 16.322431584576833 -5.77408188395082 24.98898174259809 0.8110620129290435 0.9921604157546307 0.24255170268729398 0.13014288974589033 281.9653275807689 557328.031459555 0.03699253451642976 0.05528138490985552 1.6823568315927886e-06 5.77408188395082 0.1810984028255872 LPLPS(ph)PALEYTLGSR ddPTM_PC-9_Lapatinib_30min_R1 2 LPLPSPALEYTLGSR 15 0 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 LPLPS(1)PALEYTLGSR;LPLPS(1)PALEYTLGSR 183.75 3.0536999999999994e-29 98827000.0 156603.0 168175.0 192267.0 160759.0 177057.0 138019.0 139783.0 119035.0 199924.0 145200.0 True False 154369.81250252674 167785.60112014136 176459.54943208283 172581.7531363029 166642.8553674552 132116.2491080034 147020.27977652816 124565.80065863213 177406.45382694833 170297.62653316162 0.9064707221416659 0.9852492047942248 1.0361832576552163 1.0134125568843233 0.9785389189496735 0.7757961857576255 0.8633137335469516 0.7314594054801801 1.0417435488591642 1.0 17.37769880250847 -6.643441928443201 8.727011096954952 0.8646756733710443 0.9897350036955496 0.22102781516240677 0.09219709619889074 0.3230704285883482 23.27267187351634 0.029295796506592326 0.02927263318141529 2.272783519522276e-07 6.643441928443201 0.12505933032450522 LPLQDVYK ddPTM_PC-9_AZD4547_30min_R2 1 LPLQDVYK 8 0 Q5VTE0;P68104;A0A087WVQ9;A0A087WV01;A0A2U3TZH3;Q05639 Q5VTE0 EEF1A1P5;EEF1A1;EEF1A2 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha;Elongation factor 1-alpha 2 0 90.709 0.04272 17205000.0 78369.0 82075.0 85826.0 106340.0 91366.0 91572.0 89903.0 117860.0 104520.0 99283.0 False True 103288.7118235357 108604.1386858973 84687.89116228773 81824.95593662225 78681.40799195852 85845.98836402538 97904.19283481177 99647.44515336657 110044.713818191 95807.13238939333 1.0780900048624213 1.1335704970741898 0.8839414044675384 0.8540591279160441 0.8212479178707704 0.8960292018251583 1.0218883541665276 1.0400837877953062 1.148606696325397 1.0 16.54784544135414 -7.526837632034834 3.1509268262686163 1.069901052333732 0.9410410556748112 0.23157779779755094 0.0976684974769862 0.4145265787343549 8.502708077976223 0.056493263130509584 0.03202358137226284 2.972777244506995e-08 7.526837632034834 -0.12885999665892078 LPLQDVYK ddPTM_PC-9_Lapatinib_30min_R1 1 LPLQDVYK 8 0 Q5VTE0;P68104;A0A087WVQ9;A0A087WV01;A0A2U3TZH3;Q05639 Q5VTE0 EEF1A1P5;EEF1A1;EEF1A2 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha;Elongation factor 1-alpha 2 0 100.02 0.023138 80353000.0 115180.0 114480.0 117290.0 123050.0 114950.0 86768.0 138620.0 106860.0 113610.0 132130.0 False True 113537.51207857486 114214.92859362999 107646.86895249285 132099.50748276673 108188.86700039532 83057.13490608701 145797.06532713075 111825.10571160942 100814.0454336628 154968.49444784166 0.7326489973533854 0.7370203150039103 0.694637121797192 0.852428152918708 0.6981345942985131 0.5359614236559669 0.9408174600044413 0.721598968293822 0.6505454272680836 1.0 17.241615415588576 -11.423487472996948 4.054386775833766 1.1061517660587816 0.7315286887574471 0.38374790220548727 0.10287345609124411 0.06863063731083516 0.0016824452881101912 0.0692547868274861 0.023809531636904486 3.771486235143878e-12 11.423487472996948 -0.3746230773013345 LPLQES(ph)EEEEREER ddPTM_PC-9_AZD4547_30min_R2 2 LPLQESEEEEREER 14 1 P23497;P23497-5;P23497-2;P23497-3;P23497-4;E9PHV6;P23497-7;P23497-6;C9JBL0 P23497 SP100 Nuclear autoantigen Sp-100 1 LPLQES(1)EEEEREER;LPLQES(1)EEEEREER 162.7 0.0026669000000000003 42754700.0 13397.7 15528.7 22304.3 18453.5 20660.0 21302.5 21180.6 23413.2 14490.099999999999 17868.2 True False 17657.88991052822 20548.048594720618 22008.530408629274 14199.330678732933 17791.715617558653 19970.45130743736 23065.632367740902 19795.22792181229 15256.017103874554 17242.639756656798 1.0240827483338861 1.1916996982313983 1.2764014512413928 0.8235009765979164 1.0318440719432114 1.1582015044841059 1.337708882935749 1.1480392910354706 0.8847843090838062 1.0 14.073693039840897 -8.254442332793266 24.611364942363608 0.9423921517696662 1.1264597534369376 0.21646255413730098 0.1380915309435686 651.1718613488305 2290453.468898776 0.10435108750843126 0.03748769881469805 5.566185391930806e-09 8.254442332793266 0.18406760166727143 LPLQES(ph)EEEEREER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LPLQESEEEEREER 14 1 P23497;P23497-5;P23497-2;P23497-3;P23497-4;E9PHV6;P23497-7;P23497-6;C9JBL0 P23497 SP100 Nuclear autoantigen Sp-100 1 LPLQES(1)EEEEREER;LPLQES(1)EEEEREER 161.94 0.00091379 19870300.0 46903.0 71633.0 71188.0 59263.0 61463.0 56575.0 57751.0 54420.7 53815.0 48230.0 True False 54842.75152352349 78744.25083399528 72885.39190199356 55942.6862432383 49419.76636583726 53608.10740540456 52280.4071989676 52992.214288497926 54601.94256702239 56973.7172115301 0.9625973906512922 1.382115380354002 1.279280964438166 0.9819033930248254 0.8674134106846709 0.940926975264229 0.9176232437996394 0.9301168482960347 0.9583707231932601 1.0 15.798008916488056 -5.840454311513075 5.336526052807601 0.93171345590543 1.2247172190473161 0.5804728792013546 0.10350232488214973 0.12636338734507369 6.1809352634498795 0.02843027012155427 0.04328591762628675 1.4439284999309906e-06 5.840454311513075 0.29300376314188614 LPLQES(ph)EEEEREER ddPTM_PC-9_Lapatinib_30min_R1 1 LPLQESEEEEREER 14 1 P23497;P23497-5;P23497-2;P23497-3;P23497-4;E9PHV6;P23497-7;P23497-6;C9JBL0 P23497 SP100 Nuclear autoantigen Sp-100 1 LPLQES(1)EEEEREER 59.57899999999999 0.027863 38744000.0 6163.1 11130.0 10748.0 9266.0 10878.0 10022.0 12463.0 13286.0 8109.9 10363.0 True False 6075.213063825882 11104.229168825164 9864.340928479793 9947.452550469869 10238.177426970859 9593.382422423058 13108.27315807266 13903.316062927595 7196.477660966999 12154.23074217047 0.4998434860009073 0.9136101991463592 0.8115973061342626 0.8184353877663408 0.8423550320999215 0.7893039572745429 1.078494676968081 1.1439075296380936 0.5920965146727065 1.0 13.569170965670052 -4.7592497691204345 24.931447204014106 0.8891717591513869 0.4998429682969287 0.3756548589511379 0.15001804887719122 61.52352893659884 700350.6940152531 0.037278778993857724 0.23990064962576002 1.740805422737405e-05 4.7592497691204345 -0.3893287908544582 LPLQLDDAVRPEAEGEEEGR ddPTM_PC-9_AZD4547_30min_R2 1 LPLQLDDAVRPEAEGEEEGR 20 1 P14868;P14868-2;C9J7S3;C9JLC1 P14868 DARS Aspartate--tRNA ligase, cytoplasmic 0 134.08 7.8223e-05 3349100.0 1047.9 1999.0 3829.3 4040.1 4061.8 4800.3 4096.1 5254.9 4223.2 4458.4 False True 1381.1104023259597 2645.137657424414 3778.520979979828 3108.7173639227744 3497.889181771526 4500.136482154282 4460.644964802863 4442.875950589046 4446.429730166321 4302.312773031342 0.32101580595983753 0.6148176101945029 0.8782534370037308 0.7225688897863233 0.8130253113389915 1.045980782792683 1.036801646027228 1.0326715385359269 1.033497554626517 1.0 12.070896695452507 -4.83728300237119 0.5444552080004188 1.0365840505776878 1.8066424180916406e-15 0.8673493379040581 0.08276380756836332 1.4747618165281255 0.3484883259256885 0.052005054637675116 0.9681551912519056 1.454510958482422e-05 4.83728300237119 -1.036584050577686 down LPLQLDDAVRPEAEGEEEGR ddPTM_PC-9_Lapatinib_30min_R1 2 LPLQLDDAVRPEAEGEEEGR 20 1 P14868;P14868-2;C9J7S3;C9JLC1 P14868 DARS Aspartate--tRNA ligase, cytoplasmic 0 ; 81.643 0.0015753 8728200.0 5480.700000000001 4590.9 5582.4 6156.5 7587.4 2917.9 3207.6000000000004 5216.299999999999 5580.4 2774.5 False True 5402.544212962718 4580.270053114055 5123.436620687163 6609.269547481946 7141.124049402341 2793.1082189571202 3373.6738330926646 5458.66834103938 4951.876587782865 3254.0686282111333 1.660242862158894 1.407551768701319 1.5744709795821612 2.0310787210149512 2.194521648219831 0.8583433658227984 1.036755587710909 1.6774902329088819 1.5217492786884066 1.0 11.668028962389124 -6.764640674990627 24.99999994274339 1.2498288829496318 1.7564832790160632 0.44558738744360094 0.3081129053853761 98.44214941791981 768761.7325368716 0.11803846273770253 0.1084507368376942 1.7193303321926466e-07 6.764640674990627 0.5066543960664314 LPLS(ph)PPLVEDSAFEPSR ddPTM_PC-9_AZD4547_30min_R2 1 LPLSPPLVEDSAFEPSR 17 0 O96007 O96007 MOCS2 Molybdopterin synthase catalytic subunit 1 LPLS(0.997)PPLVEDS(0.002)AFEPS(0.002)R 86.288 0.0030908000000000003 5613300.0 7151.6 9352.2 10375.0 10888.0 10136.0 11118.0 8772.9 10735.0 12957.0 8311.6 True False 9425.660037479087 12375.115757761188 10237.42072109543 8377.93981792311 8728.791360095573 10422.789702433458 9553.671104640758 9076.152415759268 13641.880567760227 8020.613413854141 1.1751794471477686 1.5429138794279054 1.2763887489468275 1.044551006965596 1.088294736287649 1.299500320565257 1.1911397061150635 1.13160327613869 1.7008525238476617 1.0 12.969496862400069 -5.517157625235849 24.820612403236137 1.2076654811719716 1.3716978384900331 0.08132883683856262 0.20239583157339502 507.65544234487174 2202418.4272472793 0.0530618438540637 0.0957890853978423 3.039781550347232e-06 5.517157625235849 0.16403235731806154 LPLS(ph)PPLVEDSAFEPSR ddPTM_PC-9_Lapatinib_30min_R1 1 LPLSPPLVEDSAFEPSR 17 0 O96007 O96007 MOCS2 Molybdopterin synthase catalytic subunit 1 LPLS(0.939)PPLVEDS(0.014)AFEPS(0.046)R 57.703 0.044657 4407800.0 4391.1 7580.1 6793.1 7321.0 7648.8 7276.6 10215.0 10719.0 9958.7 7639.4 True False 4328.4821087708815 7562.548744169959 6234.597540124313 7859.410762140066 7198.912622119387 6965.3967805830835 10743.882717621134 11217.04387163337 8837.046336239913 8959.860111139351 0.4830970634674858 0.844047635829472 0.6958364821313612 0.8771800747613068 0.803462613570198 0.7774001707820584 1.1991127745693033 1.2519217635650108 0.9862928914764251 1.0 13.12926049255423 -7.252174871169217 22.74931197924142 1.130325337026328 0.7574362404492117 0.6607588711322065 0.1267521475726362 112.97619997086883 277417.4932645015 0.047805095210161894 0.03641453780075382 5.595322572508209e-08 7.252174871169217 -0.37288909657711633 LPLS(ph)PPLVEDSAFEPSRK ddPTM_PC-9_AZD4547_30min_R2 3 LPLSPPLVEDSAFEPSRK 18 1 O96007 O96007 MOCS2 Molybdopterin synthase catalytic subunit 1 LPLS(1)PPLVEDSAFEPSRK;LPLS(1)PPLVEDSAFEPSRK;LPLS(1)PPLVEDSAFEPSRK 125.39 2.0331e-05 74207000.0 108599.0 97928.0 133155.0 156854.0 136174.0 129439.0 111822.0 134244.0 133306.0 120963.0 True False 143131.22300047422 129581.31091358577 131389.27769806868 120693.73367014248 117268.59063433859 121345.15886789738 121773.94137208242 113499.67442023168 140352.2830104071 116728.12218827165 1.2261931428110941 1.1101121862012233 1.1256008855016955 1.0339730598550594 1.0046301476965012 1.0395537647061508 1.0432271083370324 0.9723421596482741 1.2023861977667374 1.0 16.8327926520535 -4.617446830183022 0.944686151318089 1.0404997110085286 1.3612523715934843 0.4466561022713774 0.06131328681959939 2.416151624559458 1.39074207399062 0.019930024670442498 0.8554437751729111 2.4129769305159136e-05 4.617446830183022 0.3207526605849558 LPLS(ph)PPLVEDSAFEPSRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LPLSPPLVEDSAFEPSRK 18 1 O96007 O96007 MOCS2 Molybdopterin synthase catalytic subunit 1 LPLS(1)PPLVEDSAFEPSRK;LPLS(1)PPLVEDSAFEPSRK;LPLS(1)PPLVEDSAFEPSRK;LPLS(1)PPLVEDSAFEPSRK 115.8 5.8253e-05 68885000.0 108150.0 95993.0 100728.0 127982.0 141135.0 132760.0 148317.0 130617.0 124764.0 115658.0 True False 126457.6589401333 105522.55064436395 103129.7375330673 120811.58346324245 113480.60989607482 125797.83188937705 134267.34003790878 127188.44215015144 126588.43746970162 136625.87985177588 0.9255761725181643 0.7723467234673574 0.75483310808283 0.8842510920647668 0.8305938085755704 0.9207467284079263 0.9827372397057874 0.9309249630314328 0.9265333742555671 1.0 17.0598712611205 -6.836618562930441 2.9651448124949082 0.954769608966417 0.8268237428285234 0.5852569908203442 0.05050982636711285 0.19090575299927762 3.3964496106828665 0.01929654148342244 0.017177820992664943 1.4567379591766817e-07 6.836618562930441 -0.1279458661378936 LPLS(ph)PPLVEDSAFEPSRK ddPTM_PC-9_Lapatinib_30min_R1 2 LPLSPPLVEDSAFEPSRK 18 1 O96007 O96007 MOCS2 Molybdopterin synthase catalytic subunit 1 LPLS(1)PPLVEDSAFEPSRK;LPLS(1)PPLVEDSAFEPSRK 87.99 0.00072734 73193000.0 41365.0 45071.0 52570.0 42987.0 59373.0 48902.0 50367.0 47018.0 60588.0 51159.0 True False 40775.12751458803 44966.640868653994 48247.89752606835 46148.40738042824 55880.79687180923 46810.575456129794 52974.75681237626 49202.62792764785 53763.94142007532 60001.764984917405 0.6795654681964378 0.749421969169694 0.804107971460446 0.7691174983273996 0.9313192184572561 0.7801533082884567 0.882886642179484 0.8200196767547734 0.8960393320694803 1.0 15.872717318562877 -1.5228787452806938 0.09760514690536165 1.0773062136799716 0.02641988878324749 0.7082635355938303 0.04902745654125131 76.98695127615332 0.5364919982242696 0.6802009096512247 10.826566589190756 0.029999999999975394 1.5228787452806938 -1.0508863248967242 LPLVPES(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 LPLVPESPR 9 0 C9J0I9;Q86WB0;Q86WB0-2;Q86WB0-3 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 LPLVPES(1)PR;LPLVPES(1)PR;LPLVPES(1)PR 129.88 0.0012839000000000001 33811000.0 23033.8 21670.5 28391.4 40584.0 35093.0 26700.4 26695.100000000002 33935.0 31425.7 27932.4 True False 30358.069267196963 28675.06533527553 28014.911485388777 31227.985816549575 30220.94269927329 25030.81976712126 29070.912184738874 28691.12549872296 33086.79834516189 26954.49517796086 1.1262711123604723 1.0638324014586436 1.039340981918851 1.158544636446499 1.1211837765740542 0.9286324823322055 1.0785181467063232 1.0644282265090255 1.2275057695094607 1.0 14.718238269601768 -11.50028884611437 2.756406070228417 0.9266290387340292 1.0846839190975357 0.11106496823788559 0.07497089403835973 6254666.229996041 7934998.637479924 2882394.5788571155 0.01826630152901688 3.1601751514597605e-12 11.50028884611437 0.15805488036350646 LPLVPES(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LPLVPESPR 9 0 C9J0I9;Q86WB0;Q86WB0-2;Q86WB0-3 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 LPLVPES(1)PR;LPLVPES(1)PR;LPLVPES(1)PR;LPLVPES(1)PR 157.97 0.00010932 18522000.0 30017.200000000004 32403.600000000002 32722.6 37371.9 38081.3 39265.0 36388.4 29059.0 33748.700000000004 30865.399999999998 True False 35098.51909327569 35620.41526006808 33502.830885151554 35278.07360433456 30619.542633899386 37205.87427791797 32941.42732279809 28296.23204055554 34242.21089123237 36461.05268962802 0.9626304372517492 0.9769442359024628 0.9188662535429761 0.9675549936705481 0.8397876741120436 1.0204278684609076 0.9034689042910944 0.7760673363280292 0.9391448783093737 1.0 15.15406859446961 -5.617628246170419 0.7329941922724861 0.90330828904435 0.9802922097458417 0.055279313633205485 0.06907037925867612 2.9282367371529396 2.4667175229578793 0.033988683918605135 0.15645969207423716 2.411969178418851e-06 5.617628246170419 0.07698392070149174 LPLVPES(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 LPLVPESPR 9 0 C9J0I9;Q86WB0;Q86WB0-2;Q86WB0-3 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 LPLVPES(1)PR;LPLVPES(1)PR;LPLVPES(1)PR 118.23 0.0018100999999999998 25695400.0 28495.0 24465.9 24229.300000000003 25415.1 29841.8 26227.7 25430.699999999997 21572.6 23968.9 18087.8 True False 28088.656074656996 24409.250711730412 22237.260481802707 27284.211236288218 28086.56399523615 25106.002410754863 26747.37721262923 22574.941750648184 21269.270078293448 21214.252129521483 1.3240464902163191 1.1506062322019266 1.0482226922747664 1.2861264714733855 1.3239478735218408 1.183449798629369 1.2608211238994338 1.0641403530428104 1.0025934427683831 1.0 14.37274619944378 -7.88897674150141 4.29481832203973 1.009991388366572 1.2199175058199887 0.5801367520489333 0.07998355990157056 0.17116888206321507 5.505030934921078 0.05031773323651006 0.022752919971188477 1.2912884262900997e-08 7.88897674150141 0.2099261174534166 LPLVPES(ph)PRR ddPTM_PC-9_AZD4547_30min_R2 6 LPLVPESPRR 10 1 C9J0I9;Q86WB0;Q86WB0-2;Q86WB0-3 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 LPLVPES(1)PRR;LPLVPES(1)PRR;LPLVPES(1)PRR;LPLVPES(1)PRR;LPLVPES(1)PRR;LPLVPES(1)PRR 135.1 5.1695e-05 229502100.0 167573.4 153242.0 231653.0 306519.0 264274.0 239116.0 193781.0 254927.0 191484.0 220296.0 True False 220858.25545675054 202774.47968936054 228581.12986061873 235855.78022134217 227584.11680129176 224164.03871983112 211027.1335964613 215533.88978968438 201605.45331766602 212583.5040928838 1.038924710546926 0.9538580171336463 1.0752533731909184 1.109473574761897 1.0705633900072216 1.0544752269295903 0.9926787804958634 1.0138787141993457 0.9483588775052783 1.0 17.69767012640122 -7.273015960788276 8.50986200285072 0.9897980044188566 1.0507818269708236 0.3577243436221096 0.04048779553106551 0.24343808877426265 140.59190929363902 0.018228318941863372 0.012784930827838024 5.33315295218028e-08 7.273015960788276 0.06098382255196699 LPLVPES(ph)PRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 LPLVPESPRR 10 1 C9J0I9;Q86WB0;Q86WB0-2;Q86WB0-3 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 LPLVPES(1)PRR;LPLVPES(1)PRR;LPLVPES(1)PRR;LPLVPES(1)PRR;LPLVPES(1)PRR;LPLVPES(1)PRR;LPLVPES(1)PRR;LPLVPES(1)PRR 155.88 0.00013765 208341500.0 182129.0 178546.5 227442.0 232955.0 256331.0 221497.0 243276.0 244453.0 225250.0 187618.0 True False 212959.8424882803 196271.4165472896 232865.07985858832 219903.2866002997 206104.78063748032 209881.30739681658 220231.13611428463 238036.36776936258 228543.85511886663 221631.6582167297 0.9608728473259475 0.8855748232292665 1.0506850949554944 0.9922016031900106 0.9299428714102481 0.9469825253555489 0.9936808571766605 1.0740178983662658 1.0311877687409514 1.0 17.757804447385787 -7.548119537224718 5.743418212844944 1.039200903641604 0.9622234567576401 0.3690697331477615 0.04324833563435026 0.18771519485090518 18.929687649653346 0.02109636005532651 0.012301202619712672 2.8306127775950494e-08 7.548119537224718 -0.0769774468839638 LPLVPES(ph)PRR ddPTM_PC-9_Lapatinib_30min_R1 5 LPLVPESPRR 10 1 C9J0I9;Q86WB0;Q86WB0-2;Q86WB0-3 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 LPLVPES(1)PRR;LPLVPES(1)PRR;LPLVPES(1)PRR;LPLVPES(1)PRR;LPLVPES(1)PRR 124.48 0.00018849 278981000.0 157357.2 141690.8 178568.2 164376.4 164349.0 170207.9 139951.8 142321.5 182436.0 123803.9 True False 155113.25747222404 141362.72365805687 163887.01188918552 176465.1887995959 154682.314942566 162928.50489099402 147197.81941458333 148934.27646018012 161888.13654375242 145203.23915667302 1.068249292323694 0.973550758778375 1.1286732502733832 1.2152978805740793 1.0652814347734016 1.1220721096668897 1.013736472199206 1.025695275981284 1.11490719824147 1.0 17.14771411140095 -7.261140930057763 24.99999525102482 1.0407260094956887 1.0955535229178854 0.15982865107633037 0.06387587506637753 60.774617094760465 5091066.763099818 0.027386188867760536 0.01982382381437284 5.480990760184356e-08 7.261140930057763 0.054827513422196716 LPNGEPS(ph)PDPGGK ddPTM_PC-9_AZD4547_30min_R2 1 LPNGEPSPDPGGK 13 0 Q9Y3Q8 Q9Y3Q8 TSC22D4 TSC22 domain family protein 4 1 LPNGEPS(1)PDPGGK 96.67299999999999 0.0032042000000000004 7904600.0 32411.0 39451.0 40888.0 38182.0 45500.0 45781.0 46231.0 51250.0 42271.0 43302.0 True False 42717.02380932024 52202.764243647085 40345.798404255416 29379.729806019503 39183.110387169356 42918.30683280322 50345.46943868587 43330.49010784002 44505.358762043106 41786.010160103026 1.0222805107654462 1.2492880761678917 0.9655336379250031 0.7030996664541821 0.9377088225709833 1.0270975062792977 1.2048403100891252 1.0369616515627915 1.065077967279501 1.0 15.350732392408634 -7.002187199351787 23.991104988378847 1.0849670817556067 0.9758229680960224 0.11267533105371008 0.13310413980960334 123.65967972891333 1356432.967937373 0.0528211844946653 0.04579622878366745 9.949764478334606e-08 7.002187199351787 -0.10914411365958432 LPNGEPS(ph)PDPGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LPNGEPSPDPGGK 13 0 Q9Y3Q8 Q9Y3Q8 TSC22D4 TSC22 domain family protein 4 1 LPNGEPS(1)PDPGGK 89.624 0.0060143 3572600.0 34278.0 37953.0 38443.0 32410.0 45052.0 29379.0 43383.0 29076.0 29802.0 27976.0 True False 40080.588378639695 41720.72301736115 39359.62691588936 30594.172774637707 36224.384008488014 27838.31352122634 39273.4481742794 28312.785808568515 30237.79787015522 33047.82734210584 1.2128055488710903 1.2624346703786267 1.1909898496032667 0.9257544363788792 1.0961199849387666 0.8423644081969007 1.1883821519559192 0.8567215483026787 0.9149708256805617 1.0 15.012267807536514 -5.679638504546002 5.221080331055181 0.9775552568828169 1.233835738533115 0.5623221681804347 0.10020558094643993 0.14400034590521987 6.690615281237236 0.02639970055086136 0.046204018296484135 2.0910359307043414e-06 5.679638504546002 0.25628048165029804 LPNGLGGPNGFPKPTPEEGPPELNRQS(ph)PNSSSAAASVASR ddPTM_PC-9_AZD4547_30min_R2 2 LPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASR 40 2 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 LPNGLGGPNGFPKPT(0.009)PEEGPPELNRQS(0.84)PNS(0.08)S(0.037)S(0.031)AAAS(0.002)VASR;LPNGLGGPNGFPKPT(0.02)PEEGPPELNRQS(0.791)PNS(0.09)S(0.045)S(0.045)AAAS(0.008)VAS(0.001)R 66.014 5.9637e-07 165217000.0 51103.0 39145.7 80264.0 113842.0 101582.0 72911.0 72392.0 105750.0 64472.0 72633.0 True False 67352.69099156754 51798.78198911402 79199.646916434 87597.485741367 87479.0927329547 68351.86364401202 78834.74775811362 89408.76739325053 67879.8582978034 70090.14077776475 0.9609438680558958 0.7390309309458051 1.1299684383222002 1.2497832757835783 1.2480941222578679 0.9751994058727275 1.1247622972833717 1.2756254503288766 0.9684651442351997 1.0 16.09692390151178 -5.277163146919233 23.906613921031223 1.1353271347846337 0.8499874227464881 0.45037415964849037 0.1191891287109844 324.32205045383245 493103.72369266837 0.030554019623373476 0.06400144349197433 5.282467734918304e-06 5.277163146919233 -0.28533971203814557 LPNGLGGPNGFPKPTPEEGPPELNRQS(ph)PNSSSAAASVASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASR 40 2 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 LPNGLGGPNGFPKPT(0.162)PEEGPPELNRQS(0.516)PNS(0.126)S(0.126)S(0.064)AAAS(0.005)VASR;LPNGLGGPNGFPKPT(0.063)PEEGPPELNRQS(0.712)PNS(0.071)S(0.071)S(0.071)AAAS(0.012)VAS(0.001)R 47.18600000000001 0.0011324999999999998 105672000.0 67968.0 63628.0 71120.0 87488.0 85532.0 82594.0 86861.0 69572.0 68841.0 81506.0 True False 79473.63997080893 69944.56733719731 72815.770524102 82586.33099992313 68772.6185965995 78262.62524157284 78632.89726081837 67745.80871762735 69847.66939062311 96282.39259885889 0.8254223625488802 0.7264523185314599 0.7562729649591715 0.8577511294718482 0.7142803241619338 0.8128446243295826 0.816690312095031 0.7036157586971957 0.7254459253170961 1.0 16.554984372500414 -10.84441738333004 3.5401102258450887 1.0009076754510364 0.7707127820616774 0.6416757838854898 0.0513430187722655 33845293.819311395 45947872.94439372 315584.2477711606 0.012735675587502656 1.4308121410627484e-11 10.84441738333004 -0.23019489338935906 LPNGLGGPNGFPKPTPEEGPPELNRQS(ph)PNSSSAAASVASR ddPTM_PC-9_Lapatinib_30min_R1 2 LPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASR 40 2 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 LPNGLGGPNGFPKPT(0.022)PEEGPPELNRQS(0.516)PNS(0.124)S(0.149)S(0.149)AAAS(0.038)VAS(0.002)R;LPNGLGGPNGFPKPT(0.006)PEEGPPELNRQS(0.762)PNS(0.146)S(0.06)S(0.025)AAAS(0.001)VASR 76.452 5.3102e-10 139355000.0 121513.0 96788.0 82669.0 83076.0 85464.0 95482.0 64220.0 81468.0 89546.0 68908.0 True False 119780.20233724499 96563.89333263713 75872.27393156846 89185.68617341205 80437.17554868879 91398.45743941312 67544.9973691267 85253.3006935561 79460.38651881662 80818.65598586145 1.48208604654598 1.1948218162589859 0.9387965316429128 1.1035284500278542 0.9952797973126477 1.130907911354063 0.8357599683536328 1.0548715473376649 0.9831936147604033 1.0 16.302400739253756 -4.869732641838791 2.5260341678079357 1.00890449228272 1.5379291115403726 0.7728418933555303 0.0798266417126531 0.1804447708799938 1.7203495904623698 0.019968148838195227 0.19183859224672745 1.349793579932571e-05 4.869732641838791 0.5290246192576527 LPNLS(ph)SPSAEGPPGPPSGPAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LPNLSSPSAEGPPGPPSGPAPR 22 0 O60784-4;O60784;O60784-2;O60784-3 O60784-4 TOM1 Target of Myb protein 1 1 LPNLS(0.83)S(0.129)PS(0.041)AEGPPGPPSGPAPR;LPNLS(0.86)S(0.132)PS(0.008)AEGPPGPPSGPAPR 161.31 1.7978e-06 12073000.0 21137.3 34179.0 27771.0 24163.9 34207.0 25865.0 34746.0 19931.6 31345.0 24534.9 True False 24715.42740929521 37572.06523885822 28433.165962104005 22810.075023420803 27504.38390700414 24508.593867269803 31454.607340744344 19408.416619275835 31803.36132608601 28982.88315183847 0.8527594470092407 1.296353611268481 0.9810330398513305 0.7870188381163139 0.9489871577962545 0.8456230437417732 1.0852822052228812 0.6696509977146529 1.0973153070890613 1.0 14.822913497631433 -5.515706886753883 24.915709127266013 0.908431835568421 1.0905907362955076 0.12802921001202394 0.15861491532873867 464.56810293370523 1613950.2852897455 0.03903551183789637 0.07128064657416515 3.049952763737423e-06 5.515706886753883 0.18215890072708663 LPNLS(ph)SPSAEGPPGPPSGPAPR ddPTM_PC-9_Lapatinib_30min_R1 1 LPNLSSPSAEGPPGPPSGPAPR 22 0 O60784-4;O60784;O60784-2;O60784-3 O60784-4 TOM1 Target of Myb protein 1 1 LPNLS(0.487)S(0.487)PS(0.026)AEGPPGPPSGPAPR 226.72 1.8127e-41 10189000.0 4484.8 9449.7 11009.0 7950.1 18041.0 16433.0 19411.0 15599.0 15319.0 17300.0 True False 4420.845929588405 9427.81980023784 10103.882515968928 8534.776874756146 16979.86384997069 15730.198897193994 20416.00660124755 16323.786486949233 13593.612903778525 20290.281949198994 0.21787996542664742 0.4646470573372207 0.49796659017682116 0.42063372486024403 0.8368471119565202 0.775257777914465 1.006196298916069 0.8045125507777211 0.6699568265149299 1.0 14.308501292149442 -6.260075372850545 5.695759648744727 0.844586201206794 0.409770862175787 0.7815895446316138 0.11611373249897167 0.07884689356505357 10.323511816326677 0.0357671603482774 0.04357848882439231 5.494455079946517e-07 6.260075372850545 -0.43481533903100694 LPNLSS(ph)PSAEGPPGPPSGPAPR ddPTM_PC-9_AZD4547_30min_R2 2 LPNLSSPSAEGPPGPPSGPAPR 22 0 O60784-4;O60784;O60784-2;O60784-3 O60784-4 TOM1 Target of Myb protein 1 1 LPNLS(0.213)S(0.69)PS(0.097)AEGPPGPPSGPAPR;LPNLS(0.098)S(0.902)PSAEGPPGPPSGPAPR 195.09 3.3113e-19 20188200.0 14828.099999999999 22207.4 22303.0 23850.0 25358.0 28381.0 21288.0 35519.0 21652.0 19784.3 True False 19543.12735635993 29385.507760623786 22007.247647478685 18351.750978826807 21837.479410941552 26606.33158344701 23182.590759679522 30030.354695421865 22796.480516565913 19091.65767887225 1.0236474844186685 1.5391805287365492 1.1527153910701515 0.9612445020494863 1.1438231178379006 1.3936103418034183 1.2142785686616673 1.5729569008905344 1.194054539422923 1.0 14.220654753179746 -6.74550452622435 24.96156793252358 1.3069960441058233 1.173054063717751 0.05978019957902747 0.19908250683881334 606.2092861638977 949611.0039373405 0.06553763266556041 0.06532866848840996 1.796782353980185e-07 6.74550452622435 -0.13394198038807237 LPNLSS(ph)PSAEGPPGPPSGPAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LPNLSSPSAEGPPGPPSGPAPR 22 0 O60784-4;O60784;O60784-2;O60784-3 O60784-4 TOM1 Target of Myb protein 1 1 LPNLS(0.032)S(0.857)PS(0.111)AEGPPGPPSGPAPR;LPNLS(0.009)S(0.957)PS(0.035)AEGPPGPPSGPAPR 159.77 7.261399999999999e-07 15505500.0 33678.0 47445.0 45320.0 41655.0 52706.0 43017.0 53484.0 33321.0 41939.0 38513.0 True False 39379.02022917987 52155.02604691852 46400.600677057126 39321.2053973321 42378.63765318676 40761.11279289947 48417.608329372335 32446.359056517827 42552.27853420704 45495.10203125977 0.8655661482443203 1.1463877146837194 1.0199032116726585 0.8642953558014758 0.9314989034219182 0.8959450792063821 1.0642378227024198 0.7131835649961588 0.9353155973794562 1.0 15.473423613749283 -5.744534489928278 23.405056426637223 0.909095616739283 1.0241960606231204 0.13902321861908484 0.1068626782489298 187.3769162337871 259420.74127164882 0.027940560421054254 0.048188357931824646 1.8008001164305142e-06 5.744534489928278 0.11510044388383744 LPNLSS(ph)PSAEGPPGPPSGPAPR ddPTM_PC-9_Lapatinib_30min_R1 1 LPNLSSPSAEGPPGPPSGPAPR 22 0 O60784-4;O60784;O60784-2;O60784-3 O60784-4 TOM1 Target of Myb protein 1 1 LPNLS(0.115)S(0.698)PS(0.187)AEGPPGPPSGPAPR 166.34 1.0850999999999999e-08 11143000.0 4347.5 7879.8 6170.6 8994.1 14623.0 14177.0 20523.0 15624.0 13188.0 16658.0 True False 4285.503852766145 7861.554807233472 5663.277087204826 9655.556117438053 13762.903889924135 13570.682758201134 21585.580520189775 16349.948078216208 11702.628564203365 19537.313104610235 0.2193497043232056 0.4023866928445946 0.28986980230502923 0.4942110548025984 0.7044419985610249 0.6946033308438329 1.1048387464853704 0.8368575551137633 0.5989886378716983 1.0 14.253944451912373 -6.263362907994786 1.2905302938490488 0.8641861207762537 0.2952664380903658 0.7587415324208726 0.13631480936739762 0.2214377885763624 0.7502733748044966 0.055020792147075705 0.07844912459646985 5.453020018292923e-07 6.263362907994786 -0.5689196826858879 down LPNS(ph)IASR ddPTM_PC-9_AZD4547_30min_R2 3 LPNSIASR 8 0 Q9ULT0;Q9ULT0-4;H7C055;G5E9G4 Q9ULT0 TTC7A Tetratricopeptide repeat protein 7A 1 LPNS(0.998)IAS(0.002)R;LPNS(0.987)IAS(0.013)R;LPNS(0.992)IAS(0.008)R 105.17 0.0038465000000000005 19530200.0 46227.0 48287.1 45335.0 66601.0 62865.0 53299.0 47416.0 55898.0 43096.0 48762.0 True False 60926.22441866795 63894.960769293866 44733.8282786372 51247.16842519258 54137.27987888794 49966.2051043354 51635.93214303668 47260.2485082545 45373.96657777226 47054.85722199765 1.2947913991371243 1.3578823641488735 0.9506739775575094 1.0890941222797945 1.150514167399903 1.061871357267167 1.0973560476323672 1.0043649327270903 0.9642780630213115 1.0 15.522056031906091 -5.252990100878909 24.999871907241932 1.0484878075277861 1.3263369160579885 0.776830117284136 0.06129637030467422 289.6999827108739 857164.7379743098 0.016375812791463742 0.04184471368753945 5.584829244106343e-06 5.252990100878909 0.2778491085302024 LPNS(ph)IASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LPNSIASR 8 0 Q9ULT0;Q9ULT0-4;H7C055;G5E9G4 Q9ULT0 TTC7A Tetratricopeptide repeat protein 7A 1 LPNS(0.999)IAS(0.001)R;LPNS(1)IASR;LPNS(0.987)IAS(0.013)R;LPNS(0.989)IAS(0.011)R 104.82 0.0038518999999999997 26711100.0 51023.0 57443.0 60217.0 59689.0 69010.0 52074.0 69740.0 56512.5 51771.8 48253.4 True False 59660.186149814275 63145.561412438416 61652.80165424424 56344.81884434897 55487.98589243002 49343.147768962204 63133.72232612416 55029.10675494323 52528.864632377066 57001.35944629575 1.0466449700383649 1.1077904461547354 1.0816023030526296 0.9884820185286047 0.9734502199848134 0.8656486134414253 1.1075827478396556 0.965399900800424 0.9215370500394385 1.0 15.798708706599488 -5.7988320941828 4.400833823366559 0.9728518473795875 1.0826106754718112 0.3951873311587786 0.05919238118017855 0.2038498651629236 8.691562724197315 0.01693634723995317 0.027042736099635558 1.589161027199631e-06 5.7988320941828 0.1097588280922237 LPNS(ph)IASR ddPTM_PC-9_Lapatinib_30min_R1 3 LPNSIASR 8 0 Q9ULT0;Q9ULT0-4;H7C055;G5E9G4 Q9ULT0 TTC7A Tetratricopeptide repeat protein 7A 1 LPNS(0.901)IAS(0.099)R;LPNS(0.5)IAS(0.5)R;LPNS(0.771)IAS(0.229)R 101.3 0.0046297 16410000.0 56223.0 63224.0 53127.0 51954.0 51168.0 63585.0 47696.0 44881.0 54563.6 44600.9 True False 55421.24970996456 63077.608712470974 48759.10313615057 55774.87047346336 48158.39884015857 60865.61777387452 50165.46550167965 46966.33510614582 48418.07278781974 52310.106138036375 1.059475000179095 1.2058398150831737 0.9321163105172184 1.06623508517234 0.9206327877270551 1.1635537043886277 0.9590014091981113 0.897844385599422 0.9255969135305079 1.0 15.674802076819486 -4.9358280441174225 0.3770461136713997 0.9482345590351998 1.2311785647589888 0.22629840552471447 0.08966186504533775 7.85596426739587 0.9696746469431142 0.08106200449060387 1.0033362148957765 1.1592362568412403e-05 4.9358280441174225 0.28294400572378897 LPNTYPNSS(ph)SPGPGGLGGSVHYATMAR ddPTM_PC-9_AZD4547_30min_R2 2 LPNTYPNSSSPGPGGLGGSVHYATMAR 27 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 LPNT(0.003)Y(0.023)PNS(0.184)S(0.474)S(0.315)PGPGGLGGSVHYATMAR;LPNT(0.029)Y(0.067)PNS(0.157)S(0.426)S(0.32)PGPGGLGGSVHYATMAR 89.87899999999999 2.3122e-07 19313400.0 4154.200000000001 5269.4 19506.1 42105.0 26695.0 20505.2 8591.9 30201.0 16887.6 21325.5 True False 5475.149187272167 6972.630501266736 19247.436368940675 32398.342765765316 22988.860039241445 19223.00660247693 9356.562455284224 25534.129399939055 17780.2440592813 20578.900735977008 0.2660564457507807 0.3388242448284351 0.9352995388763111 1.574347589379495 1.1171082622042698 0.9341124119846869 0.45466774806521315 1.2407917083393616 0.8640035873343339 1.0 14.328878299336678 -5.273203191975169 4.560166029864444 1.028483607466077 0.2876236036541601 0.5323975219176094 0.2682870526930028 0.14767153056812618 8.372528201692747 0.07517058676078854 0.18418882597394648 5.33085424154016e-06 5.273203191975169 -0.7408600038119169 LPNTYPNSSS(ph)PGPGGLGGSVHYATMAR ddPTM_PC-9_AZD4547_30min_R2 3 LPNTYPNSSSPGPGGLGGSVHYATMAR 27 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 LPNT(0.002)YPNS(0.062)S(0.454)S(0.482)PGPGGLGGSVHYATMAR;LPNTYPNS(0.016)S(0.289)S(0.694)PGPGGLGGSVHYATMAR;LPNT(0.002)Y(0.01)PNS(0.047)S(0.227)S(0.714)PGPGGLGGSVHYATMAR 104.6 4.839e-06 24726000.0 9958.7 6280.0 48246.9 101607.0 63880.0 53970.0 30967.7 72051.0 38406.4 55978.0 True False 13125.359446171899 8309.887187906616 47607.11458203553 78183.07596250133 55011.364649063245 50595.24736826169 33723.76530761592 60917.173517267955 40436.483895780424 54018.22725837714 0.2429801959881314 0.15383487407239782 0.8813157520761221 1.4473462001731408 1.0183852273777105 0.9366328725720148 0.6243034438414682 1.127715154847495 0.7485711017943399 1.0 15.721158674570091 -5.300073565573837 5.19206467819703 0.98687596835325 0.1939983690789925 0.690112049745548 0.2081001804854016 0.09986824765300002 7.051306009603825 0.05699927235966578 0.12817985795539585 5.0110234421370526e-06 5.300073565573837 -0.7928775992742575 LPNTYPNSSS(ph)PGPGGLGGSVHYATMAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LPNTYPNSSSPGPGGLGGSVHYATMAR 27 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 LPNT(0.005)Y(0.005)PNS(0.115)S(0.391)S(0.485)PGPGGLGGSVHYATMAR;LPNT(0.011)Y(0.001)PNS(0.125)S(0.384)S(0.48)PGPGGLGGSVHYATMAR 71.169 0.00011836 22442000.0 7665.099999999999 10046.6 39997.9 37741.6 48301.0 42235.2 35061.0 29814.4 39333.1 25099.6 True False 8962.650037374153 11043.960052333681 40951.60162888049 35627.06051191812 38836.76578162966 40020.31176117971 31739.76826034187 29031.80359096799 39908.272176585495 29649.958791675726 0.3022820402667956 0.3724780911140521 1.3811689222440915 1.201588871075277 1.3098421503551347 1.349759439544836 1.0704827107298664 0.9791515662786929 1.3459806961954297 1.0 14.855742479225066 -5.252794409239516 24.505806894310243 1.208026708646864 0.3373798522257339 0.8596276791671297 0.1401950768471308 159.53625254968526 452232.3043067003 0.0363872437517767 0.09297432377537007 5.587346316513615e-06 5.252794409239516 -0.87064685642113 LPNTYPNSSS(ph)PGPGGLGGSVHYATMAR ddPTM_PC-9_Lapatinib_30min_R1 2 LPNTYPNSSSPGPGGLGGSVHYATMAR 27 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 LPNTYPNS(0.087)S(0.241)S(0.672)PGPGGLGGSVHYATMAR;LPNT(0.002)Y(0.004)PNS(0.032)S(0.132)S(0.829)PGPGGLGGSVHYATMAR 107.61 3.2182000000000003e-10 9695700.0 13035.5 5220.700000000001 28132.1 14202.8 21569.6 22240.2 14132.0 17919.7 28664.3 10346.5 True False 12849.611379582066 5208.611789908853 25819.187331046374 15247.32129115188 20300.918535465204 21289.038490438375 14863.685811592937 18752.314681081112 25435.824685539457 12134.878739155338 1.0588990344106626 0.4292265214898558 2.127683999654334 1.2564873221150281 1.6729395465618202 1.7543676330069553 1.2248730400273897 1.5453236150249647 2.096092201025978 1.0 13.566872071615478 -5.252000502127902 24.99988620583253 1.5888319064368437 0.7440627519348259 0.4517815374302242 0.3703957179357331 555.5994149783123 1471557.5584182627 0.08848499695427328 0.22754635935396772 5.597569543080996e-06 5.252000502127902 -0.8447691545020178 LPNVPSSS(ph)LPAQPNRK ddPTM_PC-9_AZD4547_30min_R2 1 LPNVPSSSLPAQPNRK 16 1 Q96CF2 Q96CF2 CHMP4C Charged multivesicular body protein 4c 1 LPNVPS(0.253)S(0.253)S(0.495)LPAQPNRK 67.01899999999999 0.011784000000000001 3393800.0 5602.1 6443.3 7534.6 7002.6 7342.1 8469.5 9234.2 6851.3 8505.0 7552.5 True False 7383.451269081265 8525.97071940107 7434.68628097982 5388.2587590915155 6322.776148871125 7939.900826116224 10056.02591098425 5792.589012211596 8954.556936698373 7288.08927380209 1.0130846359994472 1.1698499289860091 1.0201146009153168 0.739323923824624 0.8675492178175014 1.0894351767420234 1.3797890686015386 0.7948021483537189 1.2286563185890986 1.0 12.831324915877069 -6.885690889424911 8.705191648673212 1.1049521581732025 0.9646849721271686 0.1322070440207206 0.17487215173278853 0.5869472735232064 42.391979857084706 0.06383288615708581 0.05631102074161379 1.3010953075604952e-07 6.885690889424911 -0.14026718604603383 LPPPPPQAPPEEENES(ph)EPEEPSGVEGAAFQSR ddPTM_PC-9_AZD4547_30min_R2 2 LPPPPPQAPPEEENESEPEEPSGVEGAAFQSR 32 0 R4GMQ1;O60341 R4GMQ1 KDM1A Lysine-specific histone demethylase 1A 1 LPPPPPQAPPEEENES(0.992)EPEEPS(0.006)GVEGAAFQS(0.001)R;LPPPPPQAPPEEENES(0.999)EPEEPS(0.001)GVEGAAFQSR 61.177 0.00064539 3031600.0 1207.8 1105.3600000000001 1050.0 3964.2999999999997 3206.6000000000004 2313.0 2014.3799999999999 2663.3100000000004 2807.2400000000002 3139.82 True False 1591.8552761993458 1462.6460035070786 1036.0763139421877 3050.39188282445 2761.4189399449956 2168.367744354074 2193.655917628864 2251.7566362753455 2955.6249753059533 3029.895857486829 0.5253828352766299 0.4827380452344266 0.3419511305585167 1.006764597300259 0.9113907110442655 0.7156575164113541 0.7240037350486392 0.7431795487991072 0.9754873151836709 1.0 11.565052491406727 -5.757126541257442 24.999993094009326 0.846820081501259 0.45329536339293225 0.7348623871830942 0.11456920802397356 60.579087572879324 351149.6244408975 0.03301875031203728 0.05472354952082153 1.7493369065442127e-06 5.757126541257442 -0.39352471810832673 LPPPPPQAPPEEENES(ph)EPEEPSGVEGAAFQSR ddPTM_PC-9_Lapatinib_30min_R1 2 LPPPPPQAPPEEENESEPEEPSGVEGAAFQSR 32 0 R4GMQ1;O60341 R4GMQ1 KDM1A Lysine-specific histone demethylase 1A 1 LPPPPPQAPPEEENES(0.983)EPEEPS(0.016)GVEGAAFQS(0.001)R;LPPPPPQAPPEEENES(0.999)EPEEPS(0.001)GVEGAAFQSR 62.57 0.0027289000000000002 1800400.0 1361.02 0.0 1247.1 1794.12 1473.8600000000001 1757.0900000000001 1843.83 1590.77 964.82 593.57 True False 1341.6116052194998 0.0 1144.5682519452134 1926.0655698088697 1387.1704525202483 1681.9433566768455 1939.2944954705206 1664.6829815913993 856.1518115949865 696.1677836176907 1.927138308882536 0.0 1.6440982746966175 2.7666686323804273 1.992580646739652 2.4160028605984816 2.7856711285788376 2.391209448016602 1.2298067100231589 1.0 9.443291242143687 -5.517731666290374 24.060267101972194 2.1823866413889537 0.9281889845572179 0.27632670693526806 0.7074198664540964 133.32780289436928 623245.0324515114 0.18014643604398264 0.32445335660576696 3.035766287058193e-06 5.517731666290374 -1.2541976568317357 LPPQS(ph)SGVDTSPCPNSPVFR ddPTM_PC-9_AZD4547_30min_R2 1 LPPQSSGVDTSPCPNSPVFR 20 0 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 LPPQS(0.997)S(0.003)GVDTSPCPNSPVFR 221.09 5.0723e-29 17231000.0 1629.8 0.0 3765.0 1972.9 2693.5 1837.9 2590.9 0.0 2988.0 2090.5 True False 2148.04249805406 0.0 3715.0736399926996 1518.0783860011488 2319.5540181943006 1722.9758224592965 2821.4850807616363 0.0 3145.9395798771006 2017.3122312986775 1.0648041808933182 0.0 1.8415957541689323 0.752525247429775 1.1498239995803972 0.8540947681411235 1.3986357872550346 0.0 1.5594708300815938 1.0 10.978218680305902 -5.239292214317725 24.986027935808178 1.0294115158122739 0.5324023562469473 0.1370135380942853 0.5316287717866628 1616.125019032585 1823276.6273170863 0.12550800060288916 0.33150601689782766 5.763785175684169e-06 5.239292214317725 -0.49700915956532654 LPPQSCLLLPPT(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 2 LPPQSCLLLPPTPVR 15 0 O75691 O75691 UTP20 Small subunit processome component 20 homolog 1 LPPQSCLLLPPT(1)PVR;LPPQS(0.001)CLLLPPT(0.999)PVR 100.23 0.004667 5802500.0 2895.4 4758.8 5983.1 8381.4 6140.5 4552.1 5774.299999999999 6931.200000000001 1572.3 5441.4 True False 3816.0769719387195 6296.989036593945 5903.760184711909 6449.197721339165 5287.997567745353 4267.456467390479 6288.201513698684 5860.142303130943 1655.4085680859305 5250.898242233261 0.7267474622238542 1.1992213038803377 1.1243333830443796 1.228208474783974 1.0070653293590228 0.81270980135686 1.1975477763256457 1.1160266363567093 0.3152619783737931 1.0 12.358348522444423 -8.230287419546897 24.835242148967236 0.6576307302751261 1.0601555880619409 0.33873147181950825 0.21984998841504155 558.729788456109 445436.9051528359 0.14079905924200134 0.05320476368441911 5.884540828601616e-09 8.230287419546897 0.4025248577868148 LPPQSCLLLPPT(ph)PVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LPPQSCLLLPPTPVR 15 0 O75691 O75691 UTP20 Small subunit processome component 20 homolog 1 LPPQSCLLLPPT(1)PVR 95.87299999999999 0.006733800000000001 4923200.0 1370.3 1676.1 1365.0 4031.4 1647.4 1574.1 4115.8 3485.8 3188.8 1081.9 True False 1602.2647253413254 1842.4921310409973 1397.5467767913267 3805.533727975146 1324.6037959598498 1491.55142495532 3725.921628188444 3394.3014435103933 3235.430167383092 1278.0399056843132 1.2536891205156926 1.4416546172354876 1.093507933966291 2.97763294483165 1.036433831266485 1.1670616999683467 2.915340602133576 2.6558649917061468 2.5315564506185857 1.0 10.319717168547964 -7.255617198510711 24.935257238605598 2.4136792653171173 1.5208713491403822 0.21443303976259187 0.7116894706181343 632.9443704032791 2710783.597379497 0.27258168240950076 0.20529231747544385 5.551147938798884e-08 7.255617198510711 -0.892807916176735 LPPQSCLLLPPT(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 2 LPPQSCLLLPPTPVR 15 0 O75691 O75691 UTP20 Small subunit processome component 20 homolog 1 LPPQSCLLLPPT(1)PVR;LPPQSCLLLPPT(1)PVR 95.618 0.006854899999999999 4714200.0 4890.3 4509.9 5266.7 4712.700000000001 4441.4 3801.6099999999997 4044.1000000000004 5310.42 5279.7 4696.2 True False 4820.5634252288155 4499.457603637428 4833.6922560499215 5059.287679106343 4180.165584128366 3639.0240022857442 4253.48371006673 5557.1614998413315 4685.04458829424 5507.93191270684 0.8752038880705368 0.8169050879618076 0.8775875106405286 0.9185457916490449 0.7589355951341179 0.6606879060887606 0.7722469662803767 1.0089379440259452 0.8505995830278525 1.0 12.427295010110395 -7.7554488794363925 24.99726942155613 0.9473265787240067 0.8104999987519508 0.40084239640650465 0.07930616735746819 160.56901677732708 670033.4403594846 0.04194455212521943 0.02340751919485609 1.7561075924885626e-08 7.7554488794363925 -0.13682657997205594 LPPQSSGVDT(ph)SPCPNSPVFR ddPTM_PC-9_Lapatinib_30min_R1 1 LPPQSSGVDTSPCPNSPVFR 20 0 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 LPPQS(0.001)S(0.012)GVDT(0.425)S(0.425)PCPNS(0.137)PVFR 137.73 9.1588e-10 0.0 1331.0 1224.2 1613.5 1598.7 2896.6 808.3 2888.1 3012.3 1860.6 1360.5 True False 1312.0196959244931 1221.3654401146234 1480.8442582901148 1716.2737311068606 2726.2276829347093 773.7308932393299 3037.631686418168 3152.262454941801 1651.0396350134038 1595.6606122477017 0.8222423276315242 0.7654293342455616 0.9280446273622981 1.0755882033644104 1.70852602490103 0.48489690558283965 1.9036828151941765 1.975521881499235 1.0347060160165846 1.0 10.639938115987672 -5.886206553104248 0.9162004484571596 1.430685430317974 0.7250878476899962 0.2066091617636876 0.4314093955541153 1.0034919623403848 1.6395793192740147 0.1894879443198724 0.5013712071423906 1.299551356479188e-06 5.886206553104248 -0.7055975826279777 LPPQSSGVDTSPCPNS(ph)PVFR ddPTM_PC-9_AZD4547_30min_R2 3 LPPQSSGVDTSPCPNSPVFR 20 0 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 LPPQSSGVDT(0.132)S(0.184)PCPNS(0.684)PVFR;LPPQSSGVDT(0.004)S(0.005)PCPNS(0.991)PVFR;LPPQS(0.002)S(0.006)GVDT(0.276)S(0.276)PCPNS(0.44)PVFR 112.14 4.4977e-05 18124000.0 4484.0 4141.97 6867.7 6084.299999999999 4511.3 8454.2 3653.1 9929.2 2794.1 6921.6 True False 5909.818727006013 5480.780801862029 6776.629810724536 4681.658636497942 3884.983865706309 7925.557537534891 3978.218823007575 8394.870290317373 2941.7904217317946 6679.276890771075 0.8847991816556907 0.8205649940093008 1.0145753681941192 0.7009229761034024 0.5816473742950062 1.1865891573511247 0.595606214275138 1.256853163538822 0.44043546477262235 1.0 12.705476207336382 -10.668690105617655 17.683883254940685 0.9999999996870518 0.841257086186841 0.03761306416263066 0.25148177479590833 0.0 0.0 0.22204277169579817 0.05385328201680197 2.144420223920988e-11 10.668690105617655 -0.15874291350021075 LPPQSSGVDTSPCPNS(ph)PVFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LPPQSSGVDTSPCPNSPVFR 20 0 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 LPPQSSGVDT(0.006)S(0.005)PCPNS(0.989)PVFR;LPPQS(0.004)SGVDT(0.13)S(0.13)PCPNS(0.737)PVFR 143.33 3.4043e-05 17931100.0 8344.3 6352.1 9504.6 15222.3 19375.3 10467.1 8232.2 12714.099999999999 5204.4 7478.5 True False 9756.825182562674 6982.69450843358 9731.225710396227 14369.443882362462 15578.849051754818 9918.186849723554 7452.386420033264 12380.368346702475 5280.504504242525 8834.292850226575 1.1044262792706083 0.790407860234619 1.1015285405833755 1.6265528125427635 1.7634517347198042 1.1226916537489675 0.8435747542421724 1.40139890725775 0.5977280348032717 1.0 13.10889894209866 -7.844617682768264 1.2676973009405736 0.8842503317747594 1.2443999401426715 0.1529596129710632 0.3215044316402762 1.0273102677731507 2.9847328305375886 0.3047496501804046 0.11273694564863078 1.4301523933538283e-08 7.844617682768264 0.3601496083679121 LPPQSSGVDTSPCPNS(ph)PVFR ddPTM_PC-9_Lapatinib_30min_R1 2 LPPQSSGVDTSPCPNSPVFR 20 0 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 LPPQS(0.01)SGVDT(0.144)S(0.144)PCPNS(0.702)PVFR;LPPQSSGVDT(0.026)S(0.026)PCPNS(0.947)PVFR 96.59100000000001 0.0004837 25781000.0 2281.4 3740.4 7907.5 3627.2 2070.2200000000003 3712.3 3172.5 4668.2 4640.3 1514.8 True False 2248.866817642479 3731.739333609492 7257.3758738327115 3893.9563879844895 1948.45372980912 3553.533582793968 3336.75652683828 4885.1016141019545 4117.660549474738 1776.6311616558762 1.2658039925104456 2.100458110917853 4.084908578924512 2.191764093766767 1.096712571445105 2.000152681934253 1.878136891243266 2.7496430995552763 2.317678896072581 1.0 10.794928485735051 -10.776660207696638 6.926646064840007 0.9999917936910435 2.210516258144035 0.17125064036638837 0.7820307787304912 0.00010483555649980114 1.1294495022710654e-05 0.800929078007315 0.19425252086423528 1.6723985883776505e-11 10.776660207696638 1.2105244644529916 LPQFGIS(ph)TPGSDLHVNAK ddPTM_PC-9_Lapatinib_30min_R1 1 LPQFGISTPGSDLHVNAK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 LPQFGIS(0.553)T(0.203)PGS(0.244)DLHVNAK 62.525 0.011628 6997700.0 29169.0 28021.0 34575.0 21861.0 29555.0 27095.0 30746.0 27235.0 30393.0 26697.0 True False 28753.044711060535 27956.119096105114 31732.37696335958 23468.7308661582 27816.63300736565 25936.21001152992 32337.87743866661 28500.43752625568 26969.82028752144 31311.540878483578 0.9182890367052753 0.8928375388678423 1.0134402866505108 0.7495233453133971 0.8883827568665095 0.8283274883272373 1.0327782195122917 0.9102214942682808 0.8613380092723049 1.0 14.934406886526425 -7.238808310027118 24.984995913947465 0.9436029197630103 0.8825720648754993 0.16250802574439582 0.0762892399604211 1712.091894841052 1890174.615572901 0.02938697641636735 0.022745616791256123 5.770210941914547e-08 7.238808310027118 -0.06103085488751092 LPQLPITNFSR ddPTM_PC-9_Lapatinib_30min_R1 1 LPQLPITNFSR 11 0 Q60FE5;P21333-2;P21333;A0A087WWY3;F8WE98 Q60FE5 FLNA Filamin-A 0 90.82700000000001 0.03928 3726200.0 4592.4 5477.4 5773.7 4686.7 4296.4 4738.1 4016.1 3834.4 5039.5 3168.2 False True 4526.911533856982 5464.717416830453 5299.008673126517 5031.37555237288 4043.694199047395 4535.462508050561 4224.034007071781 4012.560222165403 4471.89844171238 3715.81914863886 1.2182809100155567 1.4706629139451608 1.426067432551876 1.35404209707459 1.0882376233322977 1.2205821453156418 1.1367706118364467 1.0798588579412542 1.203475805153348 1.0 11.859464571175128 -6.210897159543148 5.854395348913709 1.1312071608030894 1.381193162774115 0.6664224058347257 0.08485773965976545 0.12581387643486652 10.260112371856183 0.024443844879970453 0.031433721030138584 6.153225631674078e-07 6.210897159543148 0.2499860019710256 LPQQDHT(ph)TTTDSEMEEPYLQESK ddPTM_PC-9_Lapatinib_30min_R1 1 LPQQDHTTTTDSEMEEPYLQESK 23 0 B3KPJ4;A0A0A0MSI2;Q8IXK0-3;Q8IXK0-2;Q8IXK0-4;Q8IXK0;Q8IXK0-5 B3KPJ4 PHC2 Polyhomeotic-like protein 2 1 LPQQDHT(0.26)T(0.206)T(0.173)T(0.173)DS(0.173)EMEEPY(0.014)LQESK 68.88 0.0012425999999999997 3654900.0 23414.0 24663.0 26141.0 26907.0 38993.0 36721.0 29061.0 33339.0 34223.0 25868.0 True False 23080.11206639826 24605.894338790196 23991.7878871781 28885.83053912074 36699.50840318757 35150.528430831895 30565.636383434907 34888.05165000325 30368.44535583347 30339.249333056643 0.7607344470863665 0.8110251532156542 0.7907838333045848 0.9520944378688926 1.2096379841277416 1.158582667783182 1.0074618540456635 1.1499312744033645 1.0009623185615544 1.0 14.88889776978587 -5.947676699969354 3.5237372917309315 1.0948362632725541 0.7905957204097154 0.7883875682341366 0.06948139534790614 0.09955759033860802 2.5511452339860776 0.02036016952297706 0.03082505680440321 1.1280368834855925e-06 5.947676699969354 -0.30424054286283875 LPQQDHTTT(ph)TDSEMEEPYLQESK ddPTM_PC-9_AZD4547_30min_R2 1 LPQQDHTTTTDSEMEEPYLQESK 23 0 B3KPJ4;A0A0A0MSI2;Q8IXK0-3;Q8IXK0-2;Q8IXK0-4;Q8IXK0;Q8IXK0-5 B3KPJ4 PHC2 Polyhomeotic-like protein 2 1 LPQQDHT(0.058)T(0.225)T(0.422)T(0.292)DS(0.003)EMEEPYLQESK 75.054 0.00040376 3616200.0 7879.2 9201.9 13031.0 13648.0 9986.8 21247.0 15229.0 21676.0 15507.0 15481.0 True False 10384.621702458917 12176.234222037876 12858.200425695853 10501.664459498044 8600.30520471611 19918.421731210965 16584.351497517833 18326.47226492763 16326.668361832053 14939.014902049676 0.6951343023986218 0.8150627268179016 0.8607127384237144 0.7029690062131999 0.5756942650573382 1.3333156076093144 1.1101368869537986 1.226752391980892 1.092887882426035 1.0 13.86679739763748 -6.761073677460793 24.999999999403865 1.1641354858980169 0.7404146326534214 0.7904406133642568 0.10867606925114864 4.401769032002174 300919.9450242664 0.03693895124922075 0.03478951292722779 1.7335098852421173e-07 6.761073677460793 -0.4237208532445954 LPQQDHTTTTDS(ph)EMEEPYLQESK ddPTM_PC-9_Lapatinib_30min_R1 1 LPQQDHTTTTDSEMEEPYLQESK 23 0 B3KPJ4;A0A0A0MSI2;Q8IXK0-3;Q8IXK0-2;Q8IXK0-4;Q8IXK0;Q8IXK0-5 B3KPJ4 PHC2 Polyhomeotic-like protein 2 1 LPQQDHT(0.044)T(0.232)T(0.232)T(0.232)DS(0.235)EMEEPY(0.027)LQESK 58.516000000000005 0.0047073 6526500.0 14781.0 19069.0 21515.0 20302.0 27623.0 23586.0 19058.0 21325.0 24247.0 23247.0 True False 14570.220229496568 19024.846902095873 19746.119750301707 21795.076805486635 25998.269448907515 22577.281761651393 20044.72998848982 22315.837350739934 21516.04752777063 27265.212975319588 0.5343886454393553 0.6977699722836247 0.7242239320916309 0.7993730628554229 0.9535326011368807 0.828061815694904 0.7351759917164141 0.8184728786435734 0.7891391696535401 1.0 14.734773804298305 -4.788083048450212 0.9810054142347789 0.8384118742412511 0.38702121397423916 0.6249611613544003 0.07607804044616234 1.3879974130040529 1.0675543782292236 0.025967586522415525 0.6662410859977705 1.6289844984631262e-05 4.788083048450212 -0.4513906602670119 LPQSSSSESSPPS(ph)PQPTK ddPTM_PC-9_AZD4547_30min_R2 1 LPQSSSSESSPPSPQPTK 18 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 LPQSSSSESSPPS(0.999)PQPTK 133.94 4.609e-05 4618600.0 11488.0 11244.0 13548.0 11746.0 11783.0 15021.0 15533.0 18987.0 14790.0 13070.0 True False 15140.945034755825 14878.40311159585 13368.344667894056 9038.141173890974 10147.133839384976 14081.734495435592 16915.40690859179 16052.995427854803 15571.769205616563 12612.42327819839 1.2004786630439364 1.1796625266545242 1.0599346670359802 0.7166062361318101 0.8045348316944874 1.1164971381651159 1.341170252177586 1.2727923154627807 1.2346373779362168 1.0 13.622557872944562 -6.998454603791002 24.993866505779305 1.2340185539290862 0.9880442894845185 0.28813647432597744 0.16190072072844222 65.68580158179863 1062319.369484371 0.06324078689825642 0.055378616938983556 1.0035647449174728e-07 6.998454603791002 -0.24597426444456771 LPQSSSSESSPPS(ph)PQPTK ddPTM_PC-9_Lapatinib_30min_R1 1 LPQSSSSESSPPSPQPTK 18 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 LPQSSSSESS(0.007)PPS(0.992)PQPTK 221.81 8.930299999999998e-82 0.0 4863.6 7214.7 7135.4 6979.3 9779.4 11207.0 11809.0 12950.0 10470.0 10476.0 True False 4794.2441721249925 7197.994805419849 6548.754955440518 7492.581004262285 9204.194919040156 10727.702734792978 12420.412238119237 13551.704276299282 9290.758346012222 12286.762641607445 0.390195880881587 0.5858333082015292 0.532992713089781 0.6098092087243292 0.7491147332716761 0.873110602663152 1.0108775273365505 1.1029515806228962 0.7561599924255342 1.0 13.58481721908859 -6.450130493428831 1.196950343653613 0.9787393146414263 0.4980493462299709 0.8202277246180016 0.0940705772112235 0.18331337146705323 0.5476675010318268 0.04087869644835846 0.049659875433332334 3.547067936807252e-07 6.450130493428831 -0.4806899684114554 LPS(ph)DSER ddPTM_PC-9_AZD4547_30min_R2 2 LPSDSER 7 0 Q96T58;A0A669KB49 Q96T58 SPEN Msx2-interacting protein 1 LPS(0.992)DS(0.008)ER;LPS(0.753)DS(0.247)ER 93.598 0.013808 13679800.0 33821.0 50209.0 51937.0 54013.0 51686.0 50142.0 52625.0 61236.0 40479.0 51015.0 True False 44575.37447949835 66438.07735949094 51248.28144496706 41561.137342531336 44510.2910653019 47006.61281340337 57308.52305186652 51773.38326329158 42618.637300483635 49228.98037775753 0.9054701953493688 1.3495724845341053 1.0410185433806363 0.844241278686108 0.9041481404602153 0.9548565185120458 1.1641216741055938 1.0516850616447797 0.8657225271263072 1.0 15.587220238578126 -5.51542587866009 24.974222510808335 0.9736306409848966 1.1444648902899195 0.18329502438799572 0.132600268654226 488.35355744942257 1636448.4051123955 0.03555731657197726 0.06512892823261969 3.051926859164621e-06 5.51542587866009 0.1708342493050229 LPS(ph)DSER ddPTM_PC-9_Lapatinib_30min_R1 1 LPSDSER 7 0 Q96T58;A0A669KB49 Q96T58 SPEN Msx2-interacting protein 1 LPS(0.924)DS(0.076)ER 85.86200000000001 0.019 9552800.0 14325.0 12290.0 15702.0 15672.0 17846.0 14526.0 17030.0 14705.0 14215.0 11440.0 True False 14120.722873116729 12261.543260095345 14411.042171472815 16824.571160259424 16796.333366585943 13904.756841759876 17911.73007157003 15388.247983241774 12613.957009413927 13417.388757158189 1.0524195973365764 0.91385466144102 1.0740571382628017 1.2539378164237434 1.2518332494186013 1.0363236165711958 1.334963933426622 1.1468884342366639 0.9401201111270157 1.0 13.711816306403746 -5.521024666569438 24.61365754428658 1.1534694592199055 0.9858417988490498 0.19958580634175638 0.12048302742764336 75.05014254893271 996322.2122590094 0.032250459407269005 0.057005436447236 3.012834899719057e-06 5.521024666569438 -0.16762766037085575 LPS(ph)GSGAAS(ph)PTGSAVDIR ddPTM_PC-9_AZD4547_30min_R2 6 LPSGSGAASPTGSAVDIR 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 LPS(0.876)GS(0.124)GAAS(0.866)PT(0.127)GS(0.007)AVDIR;LPS(0.571)GS(0.429)GAAS(0.988)PT(0.011)GS(0.001)AVDIR;LPS(0.997)GS(0.003)GAAS(0.967)PT(0.032)GS(0.002)AVDIR;LPS(0.681)GS(0.32)GAAS(0.99)PT(0.008)GS(0.001)AVDIR;LPS(0.993)GS(0.008)GAAS(0.959)PT(0.038)GS(0.002)AVDIR;LPS(0.953)GS(0.047)GAAS(0.966)PT(0.026)GS(0.008)AVDIR 161.14 5.4424e-05 126609200.0 190348.4 255953.1 301120.6 450276.6 378614.2 357997.4 302398.4 448011.5 324881.7 336232.2 True False 250875.23170732163 338684.9341393284 297127.54409529525 346472.2865741217 326050.153686809 335611.7659847051 329311.2717766756 378781.6169550935 342054.2834028645 324460.8130191162 0.7732065680687944 1.0438392574679711 0.9157578732868104 1.0678401602652356 1.0048984056130044 1.0343676416940124 1.0149492899078498 1.1674186889643803 1.054223714167639 1.0 18.3076847206832 -4.003502857693262 1.0004428292056518 1.047869198176251 4.690060699292291e-53 0.5862144369033451 0.06331105108609282 5.576919361323459 1.4488377932960201 0.02005611262662353 9.12521968174309 9.919668119947354e-05 4.003502857693262 -1.047869198176251 LPS(ph)GSGAAS(ph)PTGSAVDIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LPSGSGAASPTGSAVDIR 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 LPS(0.995)GS(0.005)GAAS(0.945)PT(0.03)GS(0.025)AVDIR;LPS(0.988)GS(0.012)GAAS(0.966)PT(0.025)GS(0.009)AVDIR;LPS(0.997)GS(0.004)GAAS(0.774)PT(0.127)GS(0.099)AVDIR 115.91 0.0015260999999999999 21745200.0 43679.5 46623.6 47071.7 53946.8 55635.3 39958.0 58216.2 54134.4 47759.7 44487.5 True False 51073.57664055057 51252.082883362025 48194.06784841636 50924.3356938854 44733.96234634277 37862.53213796118 52701.54008721126 52713.42936013802 48458.095260024515 52552.73158714378 0.9718538903322189 0.9752505975521938 0.9170611382683349 0.9690140579931958 0.8512204978758182 0.720467442785099 1.0028316035260836 1.0030578386344726 0.9220851856134352 1.0 15.681478134123308 -10.050020320778929 7.833714015615485 0.9999999996015625 0.924630292187573 0.06936693293848595 0.08134123430113707 0.0 0.0 0.0846720716672688 0.020535993671937147 8.912092371904056e-11 10.050020320778929 -0.07536970741398952 LPS(ph)GSGAAS(ph)PTGSAVDIR ddPTM_PC-9_Lapatinib_30min_R1 1 LPSGSGAASPTGSAVDIR 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 LPS(0.999)GS(0.001)GAAS(0.991)PT(0.007)GS(0.002)AVDIR 188.09 1.0687999999999999e-09 29748000.0 69016.0 71319.0 56238.0 48576.0 62990.0 62156.0 71178.0 74315.0 75942.0 60953.0 True False 68031.81918401571 71153.8652373263 51614.328724957835 52148.4410847857 59285.052043104806 59497.73277271285 74863.24856337126 77767.94620024576 67388.61225528757 71488.64483523277 0.951645108685661 0.9953170241416931 0.7219933857176715 0.7294646751939077 0.8292932699975661 0.8322682981310303 1.0472047516905139 1.0878363463104601 0.9426477786871612 1.0 16.125426483805786 -7.258756833241971 23.866086299672535 1.0267419247451275 0.8389097001261439 0.4972934874712138 0.0865418756528019 113.30479214130062 1008059.3381222363 0.037655880087384574 0.027800351635184066 5.511161866837861e-08 7.258756833241971 -0.18783222461898363 LPS(ph)GSGAASPTGSAVDIR ddPTM_PC-9_AZD4547_30min_R2 5 LPSGSGAASPTGSAVDIR 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 LPS(0.978)GS(0.022)GAASPTGSAVDIR;LPS(0.624)GS(0.067)GAAS(0.308)PT(0.001)GSAVDIR;LPS(0.917)GS(0.083)GAASPTGSAVDIR;LPS(0.985)GS(0.015)GAASPTGSAVDIR;LPS(0.988)GS(0.011)GAASPTGSAVDIR 235.79 2.6553e-43 1281556600.0 153396.2 263631.8 227418.9 441451.0 304082.7 352428.3 278826.7 426871.3 228297.30000000002 306278.5 True False 202173.00076082975 348845.62374916516 224403.17679313046 339681.2922999611 261866.06595447232 330390.9026880851 303641.73614110955 360908.14911162533 240364.6291998249 295555.7829389199 0.6840434612731336 1.180303833950893 0.7592582847194908 1.1492967213237044 0.8860123234624376 1.1178630964441805 1.0273584672300615 1.2211168582893581 0.8132631573292515 1.0 18.17307092353409 -5.770557441052638 24.998520290821105 1.037378421895185 0.9051120399560983 0.14966298761529695 0.16531044497559072 388.7241504711897 1065746.4487002895 0.04314781728535725 0.06502665655216985 1.6960652608948369e-06 5.770557441052638 -0.13226638193908657 LPS(ph)GSGAASPTGSAVDIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LPSGSGAASPTGSAVDIR 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 LPS(0.999)GS(0.001)GAASPTGSAVDIR;LPS(0.95)GS(0.049)GAASPTGSAVDIR;LPS(0.989)GS(0.011)GAASPTGSAVDIR;LPS(0.941)GS(0.059)GAASPTGSAVDIR;LPS(0.9)GS(0.1)GAASPTGSAVDIR;LPS(0.625)GS(0.372)GAAS(0.003)PTGSAVDIR 226.08 6.2336e-35 1402235100.0 202368.19999999998 273920.8 240103.69999999998 179849.8 316788.2 229838.3 166606.6 169836.40000000002 143645.90000000002 178284.0 True False 236625.13930585852 301113.84674449865 245828.68280635314 169773.39878691867 254715.82629312185 217785.1749407971 150824.4167206716 165378.37445654 145746.4495361564 210605.47790463208 1.1235469355313201 1.4297531561873773 1.1672473349324328 0.806120526759502 1.2094453991764837 1.0340907421193297 0.7161466939096857 0.7852520081715437 0.692035416107051 1.0 17.684183436171132 -6.283460099727021 0.6449160989254609 0.7837460703218426 1.2942335719533735 0.47315994181574883 0.16740611420860066 0.76146540670524 0.6738984562094537 0.1164730117593551 0.2158850376583255 5.206428400267955e-07 6.283460099727021 0.5104875016315309 LPS(ph)GSGAASPTGSAVDIR ddPTM_PC-9_Lapatinib_30min_R1 5 LPSGSGAASPTGSAVDIR 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 LPS(0.496)GS(0.496)GAAS(0.008)PTGSAVDIR;LPS(0.994)GS(0.005)GAAS(0.001)PTGSAVDIR;LPS(0.992)GS(0.008)GAASPTGSAVDIR;LPS(0.927)GS(0.067)GAAS(0.006)PTGSAVDIR;LPS(0.983)GS(0.017)GAASPTGSAVDIR 223.93 8.240299999999999e-35 1867487100.0 504075.1 637776.5 563054.3 384284.6 536698.4 559511.4 588976.4 496982.9 615720.3 513528.3 True False 496886.89663794864 636299.7676991208 516762.14890645136 412546.171419846 505130.85530165205 535582.4017067775 619470.7161083411 520074.53985927696 546371.3959918008 602290.9824215526 0.824994746957991 1.0564657055644988 0.8579941655921417 0.6849615608740738 0.8386824143883715 0.8892419400892096 1.0285239762642904 0.8634938178358261 0.9071551989622636 1.0 19.200101133302766 -7.008395003517081 22.98240684836582 0.9413413417842643 0.8558320487328311 0.18863728308057415 0.09432438234539135 290.9372701178067 796481.542102321 0.03695113424963043 0.031018535301602465 9.808554205380032e-08 7.008395003517081 -0.08550929305143318 LPS(ph)LSGSDGIPYR ddPTM_PC-9_AZD4547_30min_R2 1 LPSLSGSDGIPYR 13 0 P21709 P21709 EPHA1 Ephrin type-A receptor 1 1 LPS(0.994)LS(0.004)GS(0.002)DGIPYR 74.649 0.019246 1655100.0 4301.2 4532.2 9853.4 14234.0 10277.0 5722.2 6380.5 8946.4 4372.7 5775.9 True False 5668.892129482223 5997.145017998464 9722.737477902809 10952.571213107785 8850.215943932732 5364.389929417589 6948.3521393336705 7563.939447820103 4603.831994956019 5573.687499047136 1.0170810850897836 1.075974392002372 1.7443994625757155 1.9650493887538922 1.5878565035168806 0.9624489945542645 1.2466346813526132 1.3570799312148762 0.8259939215722228 1.0 12.4444164015255 -6.756133630875988 24.999196212346558 1.1112616891995215 1.4975836840530534 0.3055556688672989 0.29847667734354993 195.936833130171 923198.8817049614 0.11129494224152031 0.10816729951173304 1.753340922032452e-07 6.756133630875988 0.3863219948535319 LPS(ph)PAPAR ddPTM_PC-9_AZD4547_30min_R2 1 LPSPAPAR 8 0 Q8IY33-4;Q8IY33-2;Q8IY33 Q8IY33-4 MICALL2 MICAL-like protein 2 1 LPS(1)PAPAR 109.83 0.0037717 70418000.0 29373.0 20238.0 66470.0 100090.0 55951.0 88970.0 62401.0 69787.0 30562.0 88506.0 True False 38713.003003645805 26779.537724339803 65588.5643692736 77015.79687508497 48183.16943456071 83406.69183535743 67954.56811324517 59003.02269572362 32177.444926440407 85407.43187912974 0.45327440659301405 0.3135504385875778 0.7679491459489827 0.9017458455381169 0.564156635721707 0.9765741692525798 0.7956516970258022 0.6908417850477678 0.37675228277532746 1.0 16.382073993524692 -5.266884097488489 24.757573033210456 0.7553566123790604 0.3834124117526776 0.4093791396998536 0.18050537694973717 340.7127090466776 1549255.7674901567 0.046546181746759466 0.10158544749259972 5.408986562278916e-06 5.266884097488489 -0.3719442006263828 LPS(ph)PDVR ddPTM_PC-9_AZD4547_30min_R2 2 LPSPDVR 7 0 Q9H425;Q9H425-2;Q9H425-3;E5RFY9 Q9H425 C1orf198 Uncharacterized protein C1orf198 1 LPS(1)PDVR;LPS(1)PDVR 85.67 0.019128 10221800.0 23256.0 34109.0 30649.0 25521.0 29259.0 36059.0 35791.0 48577.0 40827.0 31120.0 True False 30650.924245149832 45134.06721215072 30242.574234299154 19637.52774551946 25196.89289710305 33804.22502968591 38976.32966364572 41070.54083841063 42985.031870027546 30030.498272190798 1.0206598627613703 1.5029410036111959 1.007062019423925 0.6539194777099132 0.8390434507187707 1.1256631416265812 1.2978915404723421 1.36762768523369 1.4313792425426741 1.0 14.87414079213532 -7.119085570359574 3.749688741891762 1.3042688464976266 1.0109931480248562 0.23240352486745441 0.22670770349684427 0.37729137776907096 9.433288128242063 0.09976770858484882 0.07625498215289939 7.601764823044654e-08 7.119085570359574 -0.29327569847277046 LPS(ph)PDVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LPSPDVR 7 0 Q9H425;Q9H425-2;Q9H425-3;E5RFY9 Q9H425 C1orf198 Uncharacterized protein C1orf198 1 LPS(1)PDVR 82.426 0.022498 3189900.0 19350.0 33216.0 25423.0 17627.0 27590.0 18995.0 28980.0 16919.0 19858.0 21946.0 True False 22625.572820079302 36513.46496310352 26029.180737264414 16639.416337505063 22183.937556472178 17998.868761213595 26234.804602969307 16474.894177162303 20148.385682354954 25924.63607555958 0.8727440861324003 1.4084465778683213 1.0040326375807216 0.6418379910525283 0.8557087355755036 0.6942766220036549 1.011964238437358 0.6354918205657664 0.7771906854788916 1.0 14.662036116488796 -5.539953973628648 8.460255712625406 0.7954335648121061 1.1571198627040435 0.3926505901047356 0.17209375204142907 0.14307405100335824 57.30145678926765 0.043158055885851206 0.0765337208483215 2.884337167933973e-06 5.539953973628648 0.3616862978919374 LPS(ph)PDVR ddPTM_PC-9_Lapatinib_30min_R1 2 LPSPDVR 7 0 Q9H425;Q9H425-2;Q9H425-3;E5RFY9 Q9H425 C1orf198 Uncharacterized protein C1orf198 1 LPS(1)PDVR;LPS(1)PDVR 84.615 0.019837 11652800.0 23144.0 48016.0 32477.0 38202.0 59384.0 54841.0 63525.0 65506.0 52245.0 62135.0 True False 22813.962315910216 47904.821902094256 29806.866424845404 41011.50251813619 55891.14987343603 52495.57827061494 66814.01366978782 68549.64790141008 46360.61793576015 72874.95196031686 0.3130562930365055 0.657356480017719 0.40901387408222734 0.5627654141092058 0.766945958384588 0.72035146313648 0.9168309806388696 0.9406475895687441 0.6361667032179348 1.0 16.153135406828135 -6.350050339292142 1.2315123712570282 0.860953215387937 0.4631668505312597 0.6560394107149836 0.12556142328063968 0.285918481864797 0.8927258658541872 0.05073588179418728 0.06743699174605196 4.466318198313476e-07 6.350050339292142 -0.3977863648566773 LPS(ph)PDVRQDDGEDTLFSEPK ddPTM_PC-9_AZD4547_30min_R2 1 LPSPDVRQDDGEDTLFSEPK 20 1 Q9H425;Q9H425-2;Q9H425-3;E5RFY9 Q9H425 C1orf198 Uncharacterized protein C1orf198 1 LPS(0.999)PDVRQDDGEDT(0.001)LFSEPK 80.545 0.00066661 2964700.0 19583.0 15297.0 19827.0 33168.0 31899.0 30117.0 23275.0 25790.0 21732.0 28448.0 True False 25809.986648295897 20241.456100861054 19564.08102526833 25521.630040491724 27470.37446682012 28233.779229014985 25346.429910350475 21804.74809524281 22880.709153242682 27452.04417889728 0.9401845079404451 0.737338755866527 0.7126639057468616 0.9296804957100613 1.000667720327251 1.0284763875878735 0.9232984525733273 0.7942850431518824 0.8334792485446808 1.0 14.744625961091534 -5.78360379455134 24.670422515130475 0.9281829538166775 0.7907900446533885 0.32081038736540923 0.08869808056013505 244.39184060135563 272022.9960504228 0.02723587189190183 0.04043538438578558 1.6458725627114177e-06 5.78360379455134 -0.13739290916328895 LPS(ph)PDVRQDDGEDTLFSEPK ddPTM_PC-9_Lapatinib_30min_R1 1 LPSPDVRQDDGEDTLFSEPK 20 1 Q9H425;Q9H425-2;Q9H425-3;E5RFY9 Q9H425 C1orf198 Uncharacterized protein C1orf198 1 LPS(1)PDVRQDDGEDTLFSEPK 57.578 0.045114999999999995 0.0 7474.1 6526.2 6197.1 5997.2 7628.9 6926.4 7033.1 3964.5 8085.7 7441.6 True False 7367.517963417929 6511.088984868531 5687.598359497779 6438.2540940727295 7180.183100994476 6630.174018227012 7397.239504777403 4148.705143118806 7175.003319804303 8727.870644691286 0.844136933663105 0.7460111692682901 0.6516593326182317 0.7376660764316881 0.8226729512039471 0.759655394556037 0.8475422936379978 0.4753398981276435 0.8220794752690896 1.0 13.091414004375242 -8.535592672962213 24.36609006948256 1.0000000092592867 0.7348962120002369 0.37738130404207526 0.10361926492143943 1587.377020533993 3042188.068816185 0.09880341547645041 0.025510932144692768 2.9134483753159454e-09 8.535592672962213 -0.26510379725904976 LPS(ph)PTSPFSSLSQDQAATSK ddPTM_PC-9_AZD4547_30min_R2 2 LPSPTSPFSSLSQDQAATSK 20 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;H0YDG6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 LPS(0.896)PT(0.043)S(0.061)PFSSLSQDQAATSK;LPS(0.721)PT(0.182)S(0.097)PFSSLSQDQAATSK 214.3 2.4786999999999997e-28 27504000.0 45112.0 56443.0 55905.0 48595.0 51995.0 57356.0 56156.0 64555.0 67929.0 50077.0 True False 59456.67761210871 74687.09594697646 55163.663172321874 37392.1735352658 44776.391749030125 53769.520252992756 61153.77521141318 54579.50807632415 71519.58826019792 48323.819472252544 1.230380343719491 1.5455544856064547 1.1415418684774443 0.7737834869765691 0.926590493840013 1.1126918534216261 1.2654996206690072 1.129453521521899 1.4800069415304464 1.0 15.560446868068109 -5.399731219854396 6.830700577647682 1.0934867199656264 1.3848894856485598 0.26092709415087734 0.19221260143098196 0.32772908467148687 16.77888965321454 0.05354782721320028 0.11241209960328574 3.983536310224909e-06 5.399731219854396 0.29140276568293344 LPS(ph)PTSPFSSLSQDQAATSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LPSPTSPFSSLSQDQAATSK 20 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;H0YDG6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 LPS(0.482)PT(0.17)S(0.348)PFSSLSQDQAATSK;LPS(0.654)PT(0.307)S(0.039)PFSSLSQDQAATSK;LPS(0.837)PT(0.091)S(0.071)PFSSLSQDQAATSK;LPS(0.812)PT(0.167)S(0.021)PFSSLSQDQAATSK 204.51 5.026600000000001e-21 19491000.0 83645.8 158312.6 127185.40000000001 99199.4 121996.5 83331.5 106250.20000000001 73070.8 74751.70000000001 82762.8 True False 97805.38186014415 174028.8286764761 130217.98228931533 93641.57922679394 98092.16158420304 78961.44944327821 96185.41187116664 71152.7689249124 75844.80219617736 97767.0404900355 1.0003921707143477 1.7800357646523346 1.3319210813442517 0.9578031487650275 1.0033254672795446 0.8076489688907584 0.9838224762564018 0.7277786927810742 0.7757706668425493 1.0 16.5770605611292 -5.765335373835887 3.408960554265935 0.8791049225685823 1.4275083122785888 0.5537226935996392 0.196871702806017 0.15374044983300478 3.7422400015163686 0.05417820837057541 0.09249842303760279 1.716582284361465e-06 5.765335373835887 0.5484033897100065 LPS(ph)PTSPFSSLSQDQAATSK ddPTM_PC-9_Lapatinib_30min_R1 1 LPSPTSPFSSLSQDQAATSK 20 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;H0YDG6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 LPS(0.552)PT(0.224)S(0.224)PFSSLSQDQAATSK 166.3 4.3069e-08 11411000.0 20789.0 30804.0 31309.0 27011.0 41012.0 31773.0 36709.0 39391.0 41033.0 35736.0 True False 20492.545047764303 30732.675230592104 28734.894876234997 28997.479046054574 38599.7547926943 30414.14285648054 38609.61240148353 41221.24966391544 36411.43144335432 41912.91998477316 0.4889314572978734 0.733250635884047 0.6855856114695493 0.6918506049349288 0.9209512199750692 0.7256507746902365 0.9211864125789921 0.9834974437211963 0.8687400318704229 1.0 15.35510741404125 -4.0909341203712515 0.25386934421844565 1.0060035622248582 1.2708531512626223e-21 0.7531179780176714 0.0768478619090736 6.919132298065984 0.2857071156154983 0.10346739196746292 2.306364100898488 8.110840846663498e-05 4.0909341203712515 -1.0060035622248582 down LPS(ph)SPASPSPK ddPTM_PC-9_Lapatinib_30min_R1 1 LPSSPASPSPK 11 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 LPS(0.628)S(0.372)PASPSPK 142.89 0.00014554 4248100.0 69013.0 77810.0 66414.0 62120.0 77641.0 59355.0 65267.0 76908.0 59491.0 49253.0 True False 68028.86196456595 77629.83572563219 60953.69728545381 66688.51202624511 73074.30902807903 56816.525013262915 68646.20590611627 80481.42644645751 52790.497111997436 57766.31542450278 1.1776562424770838 1.3438599148164447 1.0551771709434496 1.1544532749955831 1.2649986153882864 0.9835580579398181 1.1883431616100368 1.3932241628192827 0.9138629792130597 1.0 15.817940856080988 -14.522878743944519 0.1284801973053812 0.4021718707200421 1.2466293501756653 0.15449808057379344 0.1385727097255153 299.34162109907817 2.427683387217735 45.594863896370576 1.076538942490697 3.000000009227509e-15 14.522878743944519 0.8444574794556232 LPS(ph)SPVYEDAASFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LPSSPVYEDAASFK 14 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 LPS(0.617)S(0.383)PVYEDAASFK;LPS(0.5)S(0.5)PVYEDAASFK 219.95 9.168499999999999e-16 1755124000.0 212169.0 312595.0 238507.0 224051.0 246854.0 197281.0 258528.0 196261.0 185393.0 186009.0 True False 248085.02117123554 343627.36573161575 244193.91142283427 211498.14885314248 198484.7307562663 186935.23706664785 234038.35625936688 191109.3567057186 188104.02189590258 219730.95925356637 1.129039904135443 1.5638550293455675 1.1113313856744147 0.9625323148436113 0.9033079882349113 0.8507460109475391 1.0651132505606093 0.8697425130938473 0.8560651741333967 1.0 17.745378628744632 -5.543059484342887 3.5969434573803962 0.9268420351128972 1.3496783954523088 0.6645013688105316 0.11759992866085194 0.11672195595419017 3.222815301608136 0.030612818312583532 0.06116168396884349 2.863785696727372e-06 5.543059484342887 0.42283636033941163 LPS(ph)SPVYEDAASFK ddPTM_PC-9_Lapatinib_30min_R1 2 LPSSPVYEDAASFK 14 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 LPS(0.604)S(0.396)PVYEDAASFK;LPS(0.874)S(0.126)PVYEDAASFK 198.81 7.178499999999999e-08 2195350000.0 159786.0 326578.0 284544.0 264788.0 383012.0 345131.0 432963.0 426948.0 370041.0 363406.0 True False 157507.4223388361 325821.8287058918 261149.8906916042 284261.39282687433 360483.9871905643 330370.55166965636 455379.7056357713 446785.56273030245 328363.08587552153 426220.24289194326 0.36954467781758527 0.7644447539496504 0.612711139479623 0.6669354578237177 0.845769278213178 0.7751169898174287 1.068414072841727 1.0482504530963186 0.7704070638399246 1.0 18.701239588501338 -5.3591360388638565 0.4108946964879948 0.9990664169645732 0.27480469114669764 0.6556842848432048 0.11967933132197797 2.2433619796873745 0.42324229839819666 0.10416563819882309 0.7631686293431847 4.37385076732851e-06 5.3591360388638565 -0.7242617258178756 LPS(ph)VEEAEVPKPLPPASKDEDEDIQSILR ddPTM_PC-9_Lapatinib_30min_R1 1 LPSVEEAEVPKPLPPASKDEDEDIQSILR 29 2 E9PDI4;O00515;A0A0J9YYF6;A0A0J9YVY2;A0A0J9YW63 E9PDI4 LAD1 Ladinin-1 1 LPS(0.981)VEEAEVPKPLPPAS(0.019)KDEDEDIQSILR 48.76 0.005635800000000001 3497700.0 2587.4 3281.6 2735.3 3215.5 6551.1 6143.9 8250.7 6171.1 6510.0 6754.1 True False 2550.503201528953 3274.001656820905 2510.4141925633407 3451.978596593552 6165.777177958148 5881.139719130418 8677.880875014853 6457.8318347081495 5776.775246660896 7921.537185727452 0.3219707415025831 0.41330382980714947 0.3169099801849638 0.4357713049448431 0.7783561489892736 0.7424240499339826 1.0954794090533508 0.815224581201674 0.7292492746318405 1.0 12.951564699189069 -6.313210558344753 1.905346895179433 0.8821785880547692 0.3491441183318675 0.8405755849713574 0.10547409393283762 0.13188535654010236 0.9425429178816155 0.037508824319175356 0.04732706990426397 4.861714387705793e-07 6.313210558344753 -0.5330344697229017 down LPSANQGS(ph)PFK ddPTM_PC-9_AZD4547_30min_R2 2 LPSANQGSPFK 11 0 Q56NI9;E5RFP7;E5RIE3;E5RFE4 Q56NI9 ESCO2 N-acetyltransferase ESCO2 1 LPS(0.002)ANQGS(0.998)PFK;LPSANQGS(1)PFK 160.48 0.0012068 49933000.0 64338.0 82250.0 100386.0 90033.0 92842.0 93932.0 105347.0 100950.0 92869.0 91359.0 True False 84796.14568646582 108835.70401358594 99054.81604895293 69277.28284598385 79952.49086957326 88058.41719094972 114722.67891581926 85350.49710022345 97777.86574417885 88160.54921751546 0.9618377657477069 1.2345170825224714 1.123573037238668 0.7858082040194465 0.9068964698973149 0.9988415223422241 1.3012926976301835 0.9681257417038218 1.1090886639434938 1.0 16.427845591105047 -9.650996289925047 15.687193541087385 1.000005675743583 1.043794067955592 0.007859596932892066 0.14596910686119147 0.0 0.0 0.14858779026474042 0.03603783258462638 2.2335913037908048e-10 9.650996289925047 0.04378839221200903 LPSANQGS(ph)PFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LPSANQGSPFK 11 0 Q56NI9;E5RFP7;E5RIE3;E5RFE4 Q56NI9 ESCO2 N-acetyltransferase ESCO2 1 LPSANQGS(1)PFK;LPSANQGS(1)PFK;LPSANQGS(1)PFK 133.48 5.5697e-05 40875700.0 152024.0 151832.0 144997.0 139055.0 184864.0 121219.0 137825.0 115483.0 113842.0 105653.0 True False 177758.6605891338 166904.87753726944 148454.2783841844 131264.19917239252 148641.22625732797 114862.06224614651 124769.21823341053 112451.69361435296 115506.72388209567 124807.05255131195 1.4242677553502183 1.337303254306481 1.1894702691031853 1.0517370331971092 1.1909681642086458 0.9203170806307059 0.9996968575322628 0.9010043207944572 0.9254823467176053 1.0 16.929339934224508 -4.9464409937449005 0.4921190601889851 0.9295671120388573 1.7365345799789331 0.8627409321812497 0.06439590279128632 1.3177752683293749 0.2769808439332146 0.04222044131347076 0.6064908892557924 1.1312510784964443e-05 4.9464409937449005 0.8069674679400758 LPSANQGS(ph)PFK ddPTM_PC-9_Lapatinib_30min_R1 2 LPSANQGSPFK 11 0 Q56NI9;E5RFP7;E5RIE3;E5RFE4 Q56NI9 ESCO2 N-acetyltransferase ESCO2 1 LPSANQGS(1)PFK;LPSANQGS(1)PFK 124.16 0.00052534 36923000.0 41860.0 63323.0 62381.0 63900.0 68665.0 67085.0 59304.0 63960.0 59675.0 52725.0 True False 41263.06872381618 63176.37948405349 57252.27497762357 68599.41916415113 64626.259700584116 64215.93093277308 62374.47094329943 66931.81509745964 52953.77309439157 61838.44599835358 0.6672720838572623 1.0216359493531828 0.9258362504637955 1.1093328439394734 1.0450822082803433 1.0384467121713052 1.0086681503115411 1.0823657356984953 0.8563244473478754 1.0 15.916216444306409 -4.760752936845873 24.98555961313568 1.0147752960674026 0.6672716819294737 0.6855732027000624 0.06950391912414104 9.070131803686488 329901.9069767123 0.016577714789205326 0.09633800542487711 1.734790611603926e-05 4.760752936845873 -0.34750361413792885 LPSAQT(ph)PNGTDYVASGK ddPTM_PC-9_AZD4547_30min_R2 2 LPSAQTPNGTDYVASGK 17 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3;H7C5N8;A0A2R8Y7F4;A0A2R8YET2 E7EPN9 PRRC2C Protein PRRC2C 1 LPSAQT(0.995)PNGT(0.005)DYVASGK;LPSAQT(0.712)PNGT(0.288)DYVASGK 196.65 8.212e-12 14056600.0 33145.0 37729.0 36590.0 47040.0 57341.0 49897.0 32019.0 60682.0 46572.0 41475.0 True False 43684.420541171836 49924.16141919244 36104.792692518706 36195.65476075527 49380.19192770724 46776.9327021337 34868.62897097798 51304.991233638015 49033.70084137763 40022.97287400748 1.0914836506196233 1.2473876335062353 0.9021017205837452 0.904371968436712 1.2337962020751514 1.1687520776976694 0.8712153662533916 1.2818885642290088 1.2251388969963817 1.0 15.288540712992353 -6.276306340782926 24.988070760551896 1.133211456461851 1.041823147895643 0.09009086067853123 0.14541700381742603 2316.1803525135206 3892981.2308850326 0.047336971903487415 0.05388571270711538 5.292899638958359e-07 6.276306340782926 -0.09138830856620794 LPSAQT(ph)PNGTDYVASGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LPSAQTPNGTDYVASGK 17 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3;H7C5N8;A0A2R8Y7F4;A0A2R8YET2 E7EPN9 PRRC2C Protein PRRC2C 1 LPSAQT(0.991)PNGT(0.009)DYVASGK;LPSAQT(0.988)PNGT(0.012)DYVASGK 172.37 2.2386e-05 9964400.0 31010.0 33907.0 35495.0 35330.0 43668.0 37584.0 34970.0 34074.0 32685.0 23008.0 True False 36259.38052458187 37273.062876443575 36341.33541553713 33350.574641405416 35111.56887336092 35613.02887714935 31657.388439124818 33179.593604387264 33162.95629105505 27179.1682687722 1.3340872011246379 1.371383498856691 1.3371025579650242 1.2270638421163138 1.291855899567859 1.310306059588561 1.164766637671467 1.2207729565628143 1.2201608218143303 1.0 14.730213687278095 -14.522878745280305 0.08097858197988496 0.048452541877308686 1.554657979982305 0.8468646081262298 0.04043450866967538 91.65561485389617 0.522643878389041 15.341403178309214 1.3842447442017032 3.000000000000222e-15 14.522878745280305 1.5062054381049963 LPSAQT(ph)PNGTDYVASGK ddPTM_PC-9_Lapatinib_30min_R1 1 LPSAQTPNGTDYVASGK 17 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3;H7C5N8;A0A2R8Y7F4;A0A2R8YET2 E7EPN9 PRRC2C Protein PRRC2C 1 LPS(0.037)AQT(0.952)PNGT(0.011)DYVASGK 182.28 1.5938999999999999e-06 6897400.0 28074.0 22028.0 26125.0 24154.0 27419.0 22962.0 21114.0 19331.0 25213.0 22498.0 True False 27673.659611858922 21976.995519396296 23977.103345416337 25930.365735381965 25806.268327828086 21979.968787036367 22207.17960840457 20229.188831285046 22373.246435339643 26386.74932329937 1.048771080999478 0.8328799902605175 0.908679695692742 0.9827040617119738 0.9780010417971902 0.832992670591226 0.8416034630228492 0.766641945297247 0.8478970319994732 1.0 14.687526010470691 -6.77043909564427 24.996116967687364 0.8422281520544377 0.9431872988692633 0.2551800029104794 0.0761597285170893 248.1771101199607 689291.2502316675 0.026026834055556967 0.023280568755185204 1.6965275022889044e-07 6.77043909564427 0.10095914681482565 LPSAQTPNGT(ph)DYVASGK ddPTM_PC-9_Lapatinib_30min_R1 1 LPSAQTPNGTDYVASGK 17 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3;H7C5N8;A0A2R8Y7F4;A0A2R8YET2 E7EPN9 PRRC2C Protein PRRC2C 1 LPS(0.033)AQT(0.215)PNGT(0.749)DY(0.003)VASGK 86.772 0.007356100000000001 6576000.0 39272.0 31956.0 35148.0 29660.0 32487.0 26674.0 31951.0 27703.0 31827.0 30517.0 True False 38711.97407839723 31882.00784537078 32258.26711520355 31841.2953428595 30576.178531899433 25533.215200130977 33605.26644255634 28990.18251477368 28242.308106832003 35791.82278865352 1.0815871073956433 0.8907623407064308 0.9012747773614327 0.8896248601497215 0.8542783281099751 0.7133812477476097 0.9389090530815227 0.8099666419885146 0.7890715226659311 1.0 15.127342398050523 -1.5228847094716873 0.9104607697629689 0.8462661701053262 124.08390020707138 0.4197622076646891 0.0762839710655025 869.6497426171546 1.8257792981341188 0.024206798057159626 222801.0919100302 0.02999958801108613 1.5228847094716873 123.23763403696606 LPSGS(ph)GAAS(ph)PTGSAVDIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LPSGSGAASPTGSAVDIR 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 LPS(0.024)GS(0.976)GAAS(0.995)PT(0.005)GSAVDIR;LPS(0.406)GS(0.594)GAAS(0.99)PT(0.01)GSAVDIR;LPS(0.022)GS(0.978)GAAS(0.821)PT(0.164)GS(0.015)AVDIR 163.44 2.0776e-06 20144300.0 87674.29999999999 87961.70000000001 100425.59999999999 105289.79999999999 124639.3 97476.9 109996.8 81626.2 95949.20000000001 77962.4 True False 102515.8273436424 96693.95625737663 102820.127170209 99390.75386013732 100217.12389570168 92365.03976572478 99577.10679613177 79483.5987401077 97352.27553194737 92096.36596998136 1.1131365093934027 1.0499215168695566 1.1164406552558548 1.0792038623167124 1.0881767466087344 1.0029173115889394 1.0812273182265275 0.8630481550815505 1.05706967377713 1.0 16.490856609693175 -7.078708282537826 1.3156015825091276 0.9794209869610954 1.089806275126423 0.3709372218596302 0.05673275936010356 0.43219262054245233 1.504330488155273 0.030209279468086648 0.020515362909250025 8.342413599543286e-08 7.078708282537826 0.11038528816532767 LPSGS(ph)GAAS(ph)PTGSAVDIR ddPTM_PC-9_Lapatinib_30min_R1 3 LPSGSGAASPTGSAVDIR 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 LPS(0.171)GS(0.829)GAAS(0.876)PT(0.122)GS(0.002)AVDIR;LPS(0.458)GS(0.826)GAAS(0.698)PT(0.018)GSAVDIR;LPS(0.412)GS(0.589)GAAS(0.963)PT(0.035)GS(0.002)AVDIR 171.25 7.0235e-07 94077000.0 210433.0 210714.0 219297.0 176658.0 210443.0 204849.0 179239.0 189070.0 212298.0 171221.0 True False 207432.18683131452 210226.10467922947 201267.24717089985 189650.01863381258 198065.1564868569 196088.08579634246 188519.1183968373 197854.88243396964 188386.76364295138 200816.32171235853 1.0329448575820062 1.046857660207267 1.0022454621949863 0.9443954406527766 0.9863000915361736 0.9764549222110113 0.9387639251099555 0.9852529951094775 0.9381048414619865 1.0 17.615517006158413 -5.503250262107595 3.930167292388689 0.966508543155876 1.0385156576637853 0.6705303698023657 0.02046171014802398 0.11464272726323267 3.925878327491644 0.005255583054144792 0.010819040793615403 3.1386994976993768e-06 5.503250262107595 0.07200711450790931 LPSGSGAAS(ph)PTGSAVDIR ddPTM_PC-9_AZD4547_30min_R2 6 LPSGSGAASPTGSAVDIR 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 LPSGSGAAS(0.994)PT(0.006)GSAVDIR;LPSGSGAAS(0.988)PT(0.012)GSAVDIR;LPSGSGAAS(0.844)PT(0.156)GSAVDIR;LPS(0.195)GS(0.133)GAAS(0.628)PT(0.041)GS(0.003)AVDIR;LPSGSGAAS(0.985)PT(0.015)GSAVDIR;LPSGS(0.014)GAAS(0.733)PT(0.188)GS(0.065)AVDIR 267.6 2.8985e-78 4626467000.0 72049.9 73975.4 106142.7 130225.29999999999 134752.4 108010.6 84258.09999999999 122305.6 100806.5 136740.2 True False 94960.26946898113 97886.50138220812 104735.17844559196 100203.86904582866 116044.35525573617 101256.6801073626 91756.90767043178 103406.07982309154 106134.9257894513 131952.9672184774 0.7196523994170844 0.7418287246253077 0.7937311350655696 0.7593907977826594 0.8794372548182188 0.7673694820345321 0.6953758570544903 0.7836586171789517 0.8043390613090299 1.0 17.009664267262806 -8.853950094173998 2.0818143542401026 0.999932744337125 0.7688281466212239 0.6895196799954677 0.046562776265503356 1.0832765241766766 6.05401579055548 0.04722813050192325 0.012988433274791168 1.399748161767302e-09 8.853950094173998 -0.23110459771590108 LPSGSGAAS(ph)PTGSAVDIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 9 LPSGSGAASPTGSAVDIR 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 LPSGSGAAS(0.942)PT(0.058)GSAVDIR;LPS(0.001)GS(0.002)GAAS(0.686)PT(0.232)GS(0.079)AVDIR;LPSGSGAAS(0.981)PT(0.019)GSAVDIR;LPSGSGAAS(0.996)PT(0.004)GSAVDIR;LPSGS(0.01)GAAS(0.775)PT(0.213)GS(0.002)AVDIR;LPSGS(0.005)GAAS(0.822)PT(0.172)GS(0.001)AVDIR;LPSGSGAAS(0.993)PT(0.007)GSAVDIR;LPSGSGAAS(0.596)PT(0.314)GS(0.09)AVDIR;LPSGSGAAS(0.968)PT(0.032)GSAVDIR 269.34 1.8556999999999997e-78 2687918300.0 50927.10000000001 47337.33000000001 71494.2 70420.0 99265.0 69368.20000000001 82243.29999999999 71013.0 80862.9 55868.200000000004 True False 59548.05217392565 52036.66728088476 73198.89287126334 66474.5957047203 79814.7358297648 65730.40947626304 74452.61923407142 69148.98399449304 82045.36693492299 65996.66240757218 0.9022888431263058 0.7884742255528712 1.1091302226650905 1.0072417798069329 1.209375336844416 0.9959656606622794 1.1281270373080114 1.0477648637358847 1.2431744870405665 1.0 16.01010544569027 -5.267256569700245 24.940424672315878 1.0932433226305571 0.8453815274326804 0.5775113726491332 0.08457776022883548 261.0401831372364 1119179.3637395648 0.02042526508834126 0.04444364482725632 5.40434953931965e-06 5.267256569700245 -0.24786179519787677 LPSGSGAAS(ph)PTGSAVDIR ddPTM_PC-9_Lapatinib_30min_R1 5 LPSGSGAASPTGSAVDIR 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 LPSGSGAAS(0.998)PT(0.002)GSAVDIR;LPSGS(0.001)GAAS(0.792)PT(0.187)GS(0.02)AVDIR;LPS(0.002)GS(0.037)GAAS(0.731)PT(0.176)GS(0.054)AVDIR;LPSGSGAAS(0.756)PT(0.224)GS(0.02)AVDIR;LPS(0.001)GS(0.001)GAAS(0.799)PT(0.195)GS(0.003)AVDIR 259.34 1.5991999999999998e-65 4506471000.0 109616.9 113692.1 139273.0 100051.4 126078.5 108629.7 86833.1 108176.2 129093.9 66092.8 True False 108053.7429047224 113428.85292767177 127822.51154932698 107409.51371768635 118662.81050986798 103983.86095919892 91328.89304037868 113202.46116863363 114553.98556296731 77516.8524168797 1.393938731201541 1.463279911285098 1.64896416152074 1.3856279037240342 1.5308001655137964 1.3414355422996496 1.1781811334291399 1.4603593623724485 1.4777945955145952 1.0 16.24222237064879 -6.847841496115113 5.753672318742624 1.3102667021484808 1.4866285213301025 0.3022726595538504 0.14569648844678904 0.3017111713052567 15.730251250961315 0.05105470423308063 0.04518368766441652 1.4195755277654532e-07 6.847841496115113 0.17636181918162164 LPSGSGAASPT(ph)GSAVDIR ddPTM_PC-9_AZD4547_30min_R2 1 LPSGSGAASPTGSAVDIR 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 LPSGSGAAS(0.176)PT(0.823)GS(0.001)AVDIR 243.37 6.450699999999999e-53 1089700000.0 10235.0 12756.0 17897.0 24029.0 18483.0 18345.0 14763.0 18570.0 11816.0 14108.0 True False 13489.517098774879 16879.12754282433 17659.674086307943 18489.485294349237 15916.954489803316 17197.884249967774 16076.878400279453 15700.43319614809 12440.569637157902 13614.083214141 0.9908502017060735 1.239828439221814 1.2971621965675055 1.358114608491899 1.169153606558708 1.2632421867455803 1.1809005533020644 1.153249392499672 0.9138014981600696 1.0 13.732812212688017 -8.101927042953966 3.0159083585063224 0.9567745766271302 1.223110509411369 0.5310944466008629 0.09448104163460057 0.20788147187722128 3.422330001551478 0.07792131207877624 0.025640002084230364 7.90811465106975e-09 8.101927042953966 0.26633593278423884 LPSPEPSMS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 LPSPEPSMSPK 11 0 O43303-2;O43303 O43303-2 CCP110 Centriolar coiled-coil protein of 110 kDa 1 LPSPEPS(0.063)MS(0.937)PK 85.973 0.0098375 11222000.0 72466.0 63707.0 51815.0 71243.0 58528.0 54067.0 50046.0 52825.0 49236.0 47473.0 True False 71432.6215513631 63559.49035564645 47554.97071168411 76482.44787968116 55085.49811047526 51754.68044633284 52637.137003041316 55279.44234714364 43690.52320193485 55678.6447962037 1.2829446875516186 1.1415416195614747 0.8540971298016672 1.373640614990254 0.9893469625940162 0.9295247870304055 0.9453738896789787 0.9928302412797361 0.7846908516155869 1.0 15.764836476339719 -6.504167607282805 24.009759035942643 0.9341296894926595 1.1447061763015465 0.3929653157975278 0.13647298324418047 510.57980154692336 655166.7974603412 0.04203127891256059 0.04680079072328802 3.132076728568182e-07 6.504167607282805 0.21057648680888696 LPSPT(ph)PENKDLFFVTR ddPTM_PC-9_AZD4547_30min_R2 1 LPSPTPENKDLFFVTR 16 1 A0A3B3ITG3;Q5VWQ8-2;Q5VWQ8;H0Y3A3;Q5VWQ8-3;Q5VWQ8-4;Q5VWQ8-5 A0A3B3ITG3 DAB2IP Disabled homolog 2-interacting protein 1 LPS(0.026)PT(0.974)PENKDLFFVTR 81.327 0.0052699 6526600.0 36919.0 20022.0 34590.0 56293.0 48571.0 33476.0 27379.0 31557.0 27874.0 35763.0 True False 48658.474037095235 26493.719948450023 34131.31399929551 43315.518568180174 41827.75504648797 31382.74042801426 29815.677959849025 26680.59075771919 29347.36273410118 34510.94825541 1.4099431194118939 0.7676902921465456 0.988999599393651 1.255123975371785 1.2120140755602382 0.9093560743609715 0.8639483835444904 0.7731051189976123 0.8503783355040275 1.0 15.074766494719068 -6.897240366191072 5.841213446757337 0.85759378885 1.105459443322109 0.3483131931262622 0.16792042396394258 0.25762451838228534 12.570265386292744 0.060901808674566404 0.0536552221514874 1.2669504608009357e-07 6.897240366191072 0.24786565447210895 LPSPT(ph)PENKDLFFVTR ddPTM_PC-9_Lapatinib_30min_R1 1 LPSPTPENKDLFFVTR 16 1 A0A3B3ITG3;Q5VWQ8-2;Q5VWQ8;H0Y3A3;Q5VWQ8-3;Q5VWQ8-4;Q5VWQ8-5 A0A3B3ITG3 DAB2IP Disabled homolog 2-interacting protein 1 LPS(0.003)PT(0.997)PENKDLFFVTR 67.648 0.017741 5721500.0 36085.0 22116.0 28430.0 23086.0 22132.0 32147.0 17005.0 16208.0 36758.0 17951.0 True False 35570.42128282145 22064.791760803 26092.595142973645 24783.821452638396 20830.23927318616 30772.14774831712 17885.435693895986 16961.082850213028 32617.926961100027 21053.80643179602 1.689500727483751 1.0480191233961458 1.2393291078979387 1.1771658266606464 0.989381152556232 1.4615954529649422 0.8495107880770161 0.8056064781044984 1.5492650731242388 1.0 14.36179346907983 -4.756931268399562 24.99599768192026 1.1213189770972123 1.6895015769437276 0.3527975190892907 0.2295700543658963 151.71958716180248 841130.8684525689 0.055118717341528935 0.4276366608171932 1.7501236419038545e-05 4.756931268399562 0.5681825998465153 LPSPTS(ph)PFSSLSQDQAATSK ddPTM_PC-9_Lapatinib_30min_R1 1 LPSPTSPFSSLSQDQAATSK 20 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;H0YDG6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 LPS(0.129)PT(0.274)S(0.597)PFSSLSQDQAATSK 186.98 1.2515e-11 9612400.0 6517.5 15667.0 14324.0 13882.0 15263.0 13723.0 16587.0 16373.0 15242.0 11492.0 True False 6424.559254836879 15630.724024077605 13146.336012238986 14902.928588994459 14365.260348212561 13136.099279875436 17445.793699185688 17133.749352575152 13525.285454624485 13478.376887872542 0.4766567449688629 1.1596888968241927 0.9753649212812622 1.105691635793601 1.0658004645305632 0.9746054283208924 1.294354197416969 1.271202719371322 1.0034802830594647 1.0 13.718359152270517 -4.758173963319576 24.99642398135689 1.101174555815246 0.47665588018303967 0.7368241047582356 0.11070318177745067 48.10089194365149 368146.86658717954 0.028414766903264933 0.19911327706046492 1.7451229771072438e-05 4.758173963319576 -0.6245186756322063 LPSS(ph)PASPSPK ddPTM_PC-9_AZD4547_30min_R2 2 LPSSPASPSPK 11 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 LPS(0.033)S(0.959)PAS(0.004)PS(0.005)PK;LPS(0.061)S(0.937)PAS(0.002)PS(0.001)PK 90.434 0.008739499999999999 9706700.0 45115.0 63665.0 69499.0 85854.0 83379.0 96317.0 113325.0 146832.0 116344.0 92235.0 True False 59460.63154970481 84243.4662130692 68577.39785016005 66061.68673107747 71803.26507630311 90294.28276392193 123410.70546038514 124142.48826369471 122493.7063190166 89005.88072414897 0.6680528417441076 0.9464932600819977 0.7704816501136392 0.7422171006410107 0.8067249544874346 1.0144754709384431 1.3865455232431794 1.3947672586763418 1.3762428428595028 1.0 16.44161303935077 -7.0285839988084575 2.8916117674885546 1.321393113602891 0.7926745287170751 0.774277483718248 0.12707917010827735 0.1148365649937572 1.9297682385556763 0.04963675033528109 0.039293220648655224 9.363021080656998e-08 7.0285839988084575 -0.5287185848858158 LPSS(ph)PASPSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LPSSPASPSPK 11 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 LPS(0.034)S(0.47)PAS(0.446)PS(0.05)PK 124.6 0.00050337 6315800.0 27475.0 36485.0 33151.0 33230.0 45133.0 39406.0 47484.0 41528.0 35543.0 34804.0 True False 32125.97484401439 40106.989679035134 33941.44556586762 31368.230833113572 36289.512639951376 37339.47998970165 42985.9717656106 40437.93400255312 36062.74913425025 41113.689691687614 0.7813936205903124 0.975514238196529 0.8255509495838298 0.7629631655135933 0.8826625124645139 0.9082006570004094 1.0455391400762926 0.9835637303729731 0.8771469893528294 1.0 15.327331229948888 -6.884899362018213 2.840966494063967 0.9751193440631526 0.8455277138911914 0.45584966721986253 0.06719048984300675 0.2599063410121494 4.234178906132546 0.02638979884445393 0.022835398840011657 1.3034687930448487e-07 6.884899362018213 -0.12959163017196118 LPSS(ph)PASPSPK ddPTM_PC-9_Lapatinib_30min_R1 1 LPSSPASPSPK 11 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 LPS(0.393)S(0.606)PASPSPK 113.38 0.0015706 5065500.0 55819.0 79896.0 58290.0 65544.0 64524.0 62412.0 49146.0 58519.0 62412.0 53000.0 True False 55023.01082404905 79711.0057207955 53497.62120590688 70364.32440837426 60728.82517906484 59742.78424947798 51690.539406775126 61238.006374112585 55382.503332503824 62160.979381939105 0.8851696252397852 1.2823318826915966 0.8606302818557365 1.1319693657982912 0.9769605592268005 0.9610978598390016 0.8315592823782605 0.9851518908324233 0.890952875633025 1.0 15.923721613963279 -6.615164789087706 2.917368771710244 0.9251855535770627 1.0453902465113138 0.14311735828263217 0.12015837733034787 0.4503375606815138 7.740895273569717 0.03961874021846627 0.03994487413342396 2.425689514635635e-07 6.615164789087706 0.12020469293425118 LPSS(ph)PLGCR ddPTM_PC-9_AZD4547_30min_R2 2 LPSSPLGCR 9 0 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3 C9JWC4 HJURP Holliday junction recognition protein 1 LPS(0.317)S(0.683)PLGCR;LPS(0.032)S(0.968)PLGCR 108.43 0.002436 66981000.0 179525.0 180325.0 252320.0 268130.0 255220.0 265360.0 250710.0 268770.0 225520.0 246490.0 True False 236610.2156480275 238611.52980242998 248974.07193704104 206316.77106720468 219787.10841787595 248766.99725110087 273022.704310374 227237.7722201789 237440.5267917951 237860.46012571678 0.9947437902162112 1.003157606255013 1.0467232418765622 0.8673857393454958 0.9240169984608266 1.0458526697527601 1.147827193162213 0.9553406736877433 0.9982345391339958 1.0 17.85975594493238 -6.780038801881992 24.96940033968701 1.0340583336931866 0.9680749225125868 0.18592825361636178 0.06475279525287331 440.5443005865006 591419.1687560765 0.024515699216916455 0.021659083251872564 1.6594386388745722e-07 6.780038801881992 -0.0659834111805998 LPSS(ph)PLGCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LPSSPLGCR 9 0 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3 C9JWC4 HJURP Holliday junction recognition protein 1 LPS(0.12)S(0.88)PLGCR;LPS(0.178)S(0.822)PLGCR;LPS(0.315)S(0.685)PLGCR;LPS(0.053)S(0.947)PLGCR 112.71 0.0021498000000000003 48569000.0 196271.0 204702.0 230300.0 214787.0 252968.0 218039.0 271898.0 211902.0 224777.0 187982.0 True False 229495.80377104814 225023.46173161198 235791.2254176134 202753.18073884957 203400.73634598232 206604.65100427758 246141.85306894963 206339.79702872745 228063.93838869434 222061.6485353063 1.0334778890671878 1.0133377970299755 1.0618277715799458 0.9130490657715403 0.9159651731291321 0.9303932145285719 1.1084392766264397 0.9292005098121247 1.027029835601863 1.0 17.760600726189217 -5.7408988872950015 24.981847859089008 0.9731762048397177 1.0339268150093925 0.18894422250766363 0.058112852532206466 429.72831975364437 522641.9890260124 0.016206098289270283 0.028028622498304723 1.8159384014414265e-06 5.7408988872950015 0.06075061016967487 LPSS(ph)PLGCR ddPTM_PC-9_Lapatinib_30min_R1 2 LPSSPLGCR 9 0 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3 C9JWC4 HJURP Holliday junction recognition protein 1 LPS(0.228)S(0.772)PLGCR;LPS(0.058)S(0.942)PLGCR 77.533 0.02292 64180000.0 254820.0 325460.0 337200.0 294100.0 375880.0 290940.0 296580.0 306120.0 296950.0 317620.0 True False 251186.22007173506 324706.4173662028 309476.71762964095 315729.0950888398 353771.47740851284 278497.174414265 311935.4612229148 320343.45274600363 263504.363977873 372520.19379795366 0.6742888687746487 0.8716478268083262 0.830764943168407 0.8475489392129008 0.9496706038985643 0.7476028925436333 0.8373652392978765 0.8599358050365198 0.7073559188600436 1.0 18.506959108608946 -4.755879464856076 24.975721557835197 0.8446426577008734 0.6742885943416302 0.29899877253822305 0.0804041684835047 224.18044846893102 1006935.9830580025 0.01878538838866406 0.16045059510366963 1.7543673456472038e-05 4.755879464856076 -0.1703540633592432 LPSS(ph)PVYEDAASFK ddPTM_PC-9_AZD4547_30min_R2 13 LPSSPVYEDAASFK 14 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 LPS(0.018)S(0.982)PVYEDAASFK;LPS(0.002)S(0.998)PVYEDAASFK;LPS(0.018)S(0.982)PVYEDAASFK;LPS(0.291)S(0.709)PVYEDAASFK;LPS(0.047)S(0.953)PVYEDAASFK;LPS(0.002)S(0.998)PVYEDAASFK;LPS(0.227)S(0.773)PVYEDAASFK;LPS(0.029)S(0.971)PVYEDAASFK;LPS(0.059)S(0.94)PVY(0.001)EDAASFK;LPS(0.061)S(0.938)PVYEDAAS(0.001)FK;LPS(0.002)S(0.998)PVYEDAASFK;LPS(0.036)S(0.964)PVYEDAASFK;LPS(0.025)S(0.975)PVYEDAASFK 222.55 9.095200000000001e-17 5720904300.0 856387.2 1004014.0 1037590.4 919807.5 916831.2 1121028.0 1091221.0 1310109.5 1134200.6 917408.5 True False 1128700.5156396616 1328541.8909361246 1023831.2733464757 707760.0917592134 789545.0135384804 1050929.9419445572 1188337.5550248153 1107662.1800963385 1194152.128199584 885290.3076524162 1.2749495909796105 1.500685006321947 1.1564921297528241 0.7994666671953389 0.8918487039942524 1.1871020532590928 1.3423139785366112 1.251185255866633 1.348881963212946 1.0 19.75579110108056 -5.3597209731758415 6.604462546119634 1.1199106750234813 1.3859853040562145 0.26290864031727945 0.17852824325358502 0.340574836598264 19.224731998930757 0.052930490082341436 0.11155179954791059 4.367963763569293e-06 5.3597209731758415 0.26607462903273316 LPSS(ph)PVYEDAASFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 11 LPSSPVYEDAASFK 14 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 LPSS(1)PVYEDAASFK;LPS(0.011)S(0.967)PVY(0.022)EDAASFK;LPS(0.038)S(0.962)PVYEDAASFK;LPS(0.12)S(0.88)PVYEDAASFK;LPS(0.098)S(0.902)PVYEDAASFK;LPS(0.034)S(0.965)PVYEDAAS(0.001)FK;LPS(0.007)S(0.993)PVYEDAASFK;LPS(0.131)S(0.869)PVYEDAASFK;LPS(0.01)S(0.99)PVYEDAASFK;LPS(0.291)S(0.708)PVYEDAASFK;LPS(0.131)S(0.869)PVYEDAASFK 249.39 2.415e-35 2729142000.0 483016.10000000003 779208.0 593924.1000000001 548355.0 630061.0 487604.10000000003 661085.0 474120.8 446164.79999999993 439590.8 True False 564781.185727168 856562.6206337293 608085.5030136926 517632.44714089663 506605.0699807325 462033.28261803987 598462.2429590736 461675.631372511 452689.1161391262 519285.13224114117 1.087612855946162 1.649503456678914 1.1710050322244063 0.9968173841351632 0.9755816959255433 0.8897487217166942 1.1524732864509684 0.8890599840207287 0.871754433225156 1.0 18.98616739435696 -5.577150423898226 3.756248943328073 0.9690336561850839 1.3790469373456589 0.5403057110254932 0.1480500510029776 0.14664184133349745 4.244632245017165 0.03869094413628803 0.07386622174570737 2.647582952815522e-06 5.577150423898226 0.410013281160575 LPSS(ph)PVYEDAASFK ddPTM_PC-9_Lapatinib_30min_R1 7 LPSSPVYEDAASFK 14 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 LPS(0.022)S(0.978)PVYEDAASFK;LPS(0.084)S(0.915)PVY(0.001)EDAASFK;LPS(0.181)S(0.817)PVY(0.002)EDAASFK;LPS(0.003)S(0.997)PVYEDAASFK;LPS(0.26)S(0.74)PVYEDAASFK;LPS(0.04)S(0.96)PVYEDAASFK;LPS(0.378)S(0.606)PVYEDAAS(0.016)FK 188.12 3.8407e-06 2107232000.0 229690.3 373384.10000000003 384034.7 382056.10000000003 516767.50000000006 462054.9 545473.8999999999 548509.8 483479.99999999994 482285.3 True False 226414.87420195775 372519.55205710087 352460.8493828113 410153.78009578784 486372.2516539955 442293.8890295792 573715.8695177091 573995.5677414726 429025.3911298939 565647.6715002328 0.4002754463771616 0.6585717060747196 0.6231102276935055 0.7251046910667236 0.8598501791124148 0.7819247056325894 1.0142636457710108 1.0147581200486502 0.7584675280144194 1.0 19.109544186767252 -4.63926003235169 0.39723522931585287 0.968856627894762 3.194571525679793e-21 0.7752887842391988 0.08889501401585007 2.9980680185989392 0.34312791830414113 0.0733773153836658 1.421468113887415 2.2947742483775236e-05 4.63926003235169 -0.968856627894762 down LPSSIEYS(ph)DLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LPSSIEYSDLSR 12 0 Q15386-3;Q15386-2;Q15386 Q15386-3 UBE3C Ubiquitin-protein ligase E3C 1 LPSSIEY(0.001)S(0.971)DLS(0.028)R 62.162 0.029934 1597000.0 5074.4 6005.0 9308.3 9142.9 8843.2 5790.7 8508.6 6701.9 7939.1 5907.2 True False 5933.395696031545 6601.136714337565 9530.245173924328 8630.652954681738 7110.438441442367 5487.025498055258 7702.603811070558 6525.982226250016 8055.194318198415 6978.128598630531 0.8502846590124441 0.9459752168558556 1.3657308029253938 1.236814832615082 1.0189606483947289 0.7863176237726682 1.103820845689517 0.9352052106822379 1.1543487919926354 1.0 12.76862446959721 -5.010115174149011 24.581840145045096 1.0732140449686793 0.8742071240515957 0.19040953909715397 0.15168483821265039 661.3733834034678 1607302.8043567815 0.04122619940841553 0.129598202460297 9.769780936885907e-06 5.010115174149011 -0.1990069209170836 LPSSPAS(ph)PSPK ddPTM_PC-9_AZD4547_30min_R2 2 LPSSPASPSPK 11 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 LPS(0.007)S(0.239)PAS(0.552)PS(0.202)PK;LPS(0.003)S(0.019)PAS(0.489)PS(0.489)PK 113.38 0.0015706 19045300.0 47904.0 60139.0 47940.0 48631.0 55540.0 62106.0 62493.0 61065.0 56719.0 57483.0 True False 63136.47553490101 79577.7556677572 47304.28427656043 37419.87429146025 47829.2296901843 58222.50200209861 68054.7559350174 51628.80738410246 59717.05054586653 55470.5376664635 1.1381983696378015 1.4345949943057519 0.8527821482639019 0.6745900772850024 0.862245647910873 1.0496112792737342 1.226863102431439 0.9307428692063376 1.07655438468862 1.0 15.759434088877528 -5.2662120214769805 24.996781183094022 0.9558650507680656 1.2863966872854258 0.4145684149025135 0.15550081927373388 374.8475491627444 1963278.9094110008 0.04444049214117486 0.09760847785158754 5.417363515049779e-06 5.2662120214769805 0.3305316365173602 LPSSPAS(ph)PSPK ddPTM_PC-9_Lapatinib_30min_R1 1 LPSSPASPSPK 11 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 LPS(0.002)S(0.038)PAS(0.855)PS(0.105)PK 113.07 0.0016091999999999999 8633400.0 32578.0 37609.0 28255.0 30362.0 24893.0 22960.0 21581.0 22712.0 22178.0 22278.0 True False 32113.43174592649 37521.918671190055 25931.982967454096 32594.922764662853 23428.842681520993 21978.054322374115 22698.358583356025 23767.282434232373 19680.080095306494 26128.722616430932 1.2290471377935674 1.436041065688935 0.9924703686489015 1.2474747902205399 0.8966700372404685 0.8411453803161932 0.8687129071163342 0.9096228232484056 0.7531971763108987 1.0 14.673348975313889 -5.977600624798751 1.0393418899305478 0.8573722096084383 1.3145395312575432 0.6640066685683483 0.11922779352196486 0.31372278883933974 0.6859360023001919 0.0464192466876566 0.10024272836248915 1.0529296980426278e-06 5.977600624798751 0.4571673216491049 LPSSPASPS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LPSSPASPSPK 11 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 LPSS(0.003)PAS(0.177)PS(0.82)PK 92.19 0.0077822 5734200.0 26347.0 35329.0 26306.0 27486.0 31305.0 21023.0 28111.0 19617.0 19970.0 19615.0 True False 30807.026723029918 38836.22963877302 26933.234806060565 25946.04853081431 25171.009974822824 19920.516871123637 25448.122573984467 19102.07453592959 20262.023470471766 23171.04422774544 1.3295484838849434 1.6760673043932044 1.1623660350106366 1.1197617282930232 1.0863131470217726 0.8597159746158717 1.0982725821010868 0.8243942028756914 0.8744544816935632 1.0 14.500035441803256 -5.681693940166846 1.1827443920398775 0.9392839776382786 1.5238823867646352 0.7205678264529027 0.12768906001273034 0.2693915391083294 0.7160058580050744 0.04347020210011499 0.13143546207113668 2.0811628258283e-06 5.681693940166846 0.5845984091263565 LPSSPASPS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 LPSSPASPSPK 11 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 LPS(0.001)S(0.001)PAS(0.375)PS(0.623)PK 153.75 0.00045528 10505000.0 41055.0 47492.0 24215.0 34357.0 36513.0 28043.0 32180.0 29547.0 26523.0 29169.0 True False 40469.54817143507 47382.03519189977 22224.13617260311 36883.72839159219 34365.37712732 26843.666261425875 33846.12294205069 30919.86148662665 23535.700440428103 34210.82278475063 1.182945772045981 1.385001333935183 0.6496229661716716 1.0781304098898492 1.0045177031707717 0.7846542139697196 0.989339635442428 0.9038035033875036 0.6879606663806715 1.0 15.062165181498147 -5.247909287180838 24.96630776978959 0.8948047376158208 1.2839735873147349 0.5554522682483982 0.14183586129391326 551.6837514110659 1017986.4033600122 0.03478586352709092 0.09094596474216675 5.650549877740774e-06 5.247909287180838 0.3891688496989141 LPSSPVY(ph)EDAASFK ddPTM_PC-9_AZD4547_30min_R2 1 LPSSPVYEDAASFK 14 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 LPSS(0.001)PVY(0.999)EDAASFK 186.46 7.3544e-06 3229400.0 5667.7 8572.8 8388.1 10162.0 10981.0 12762.0 7046.7 10564.0 8844.5 10309.0 True False 7469.910704516499 11343.789949758891 8276.868313312827 7819.30790133493 9456.477695857293 11963.990122545041 7673.842648733262 8931.576536570194 9312.002213595388 9948.085047815386 0.7508893087073981 1.1402988510085168 0.832006187475291 0.7860113643732932 0.9505827152064757 1.2026425251734605 0.771388926798374 0.8978186750154072 0.9360597711858442 1.0 13.280203126106835 -6.486265045584712 24.758733034541642 0.9581201806716004 0.8897822612830496 0.0740589845744557 0.14024723826582175 1882.011234655653 1272644.7504449214 0.04436425674605409 0.050287519941508964 3.263885796873001e-07 6.486265045584712 -0.06833791938855083 LPSSPVY(ph)EDAASFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LPSSPVYEDAASFK 14 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 LPSS(0.01)PVY(0.989)EDAASFK 100.04 0.0029824 4165700.0 7811.9 9904.2 12200.0 16138.0 18916.0 15495.0 14578.0 13439.0 12654.0 8875.9 True False 9134.300377941989 10887.423521422495 12490.894268757644 15233.84018010193 15209.545589642179 14682.414922611457 13197.066304419832 13086.240489797516 12839.040810983965 10485.030408414263 0.8711753826304299 1.0383778680017286 1.1913073956117162 1.4529133046554386 1.4505962307402067 1.4003216348165077 1.2586578951482252 1.2480879864016203 1.2245115474992425 1.0 13.356043425056901 -5.184202756934815 2.1549510169718977 1.310243086764034 0.8862554567984995 0.522155096427112 0.12853056128868715 0.27179816657824396 2.249435187261678 0.03605411781188503 0.158068202537881 6.5433061861941805e-06 5.184202756934815 -0.4239876299655345 LPSSPVYEDAAS(ph)FK ddPTM_PC-9_AZD4547_30min_R2 2 LPSSPVYEDAASFK 14 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 LPSSPVYEDAAS(1)FK;LPS(0.136)S(0.094)PVY(0.001)EDAAS(0.77)FK 84.62 0.007215300000000001 7788600.0 13102.2 17804.8 12747.5 15034.3 11856.0 18967.2 17408.0 14966.4 17765.6 16154.1 True False 17268.427057310033 23559.853408159193 12578.459820931472 11568.374412619538 10209.999049456701 17781.177985608552 18957.27827623549 12653.686773658084 18704.653346808773 15588.549875925357 1.1077635312299987 1.511356322151848 0.8069037800852401 0.7421071558737803 0.6549678533745348 1.1406563232074234 1.2161027438166478 0.8117295626837095 1.1998969433132367 1.0 13.928199107192826 -5.268085423921378 24.977642053301828 0.9386663093183297 1.3095599321277498 0.33169772973752043 0.20586706049003115 538.9277881530331 2025442.7397327807 0.05606565885440427 0.12122086496163179 5.3940451345170196e-06 5.268085423921378 0.37089362280942006 LPSSPVYEDAAS(ph)FK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LPSSPVYEDAASFK 14 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 LPS(0.002)S(0.009)PVY(0.144)EDAAS(0.845)FK 67.102 0.035095 3618700.0 6698.1 9682.9 6411.7 9154.2 7540.7 7861.9 9960.3 6469.9 8207.6 5145.3 True False 7831.956036494738 10644.154319943253 6564.579244507661 8641.31985231683 6063.153966367877 7449.608123916038 9016.788277672707 6300.071980425695 8327.620622746315 6078.1021598276075 1.2885528789329983 1.7512299135566276 1.0800376617384548 1.4217134929765516 0.997540647875495 1.2256470733830722 1.4834874506170606 1.0365195935772793 1.3701021147335422 1.0 12.5694052083275 -1.5228787452803376 0.19486840654407583 1.1039286240023236 2.8045764511736806 0.16309310933084864 0.2145529264349442 95.22875373872556 1.1316195481413742 0.4023036648093947 49.06125221922332 0.029999999999999995 1.5228787452803376 1.700647827171357 LPSSPVYEDAAS(ph)FK ddPTM_PC-9_Lapatinib_30min_R1 2 LPSSPVYEDAASFK 14 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 LPSSPVY(0.011)EDAAS(0.989)FK;LPSSPVYEDAAS(1)FK 150.37 3.1029e-08 2572800.0 8101.5 16530.6 11444.9 15208.400000000001 17902.7 17901.3 23184.0 18988.0 19909.2 18613.2 True False 7985.971124366857 16492.324411337035 10503.94450059159 16326.876469735163 16849.69838406243 17135.703128968467 24384.354079816785 19870.251799101985 17666.816242829653 21830.466819469988 0.36581769828414257 0.7554728237248682 0.4811598665047058 0.7478940603859957 0.7718432465692695 0.7849444205968884 1.1169872949335675 0.9102073704342528 0.809273406241277 1.0 14.41405536058514 -6.222139129081946 0.8358205026920348 0.9521569241508104 0.5133761749594501 0.6458218185485828 0.12512274963037562 0.4295203573332868 0.6401513816914737 0.06437195433102867 0.11357117749681589 5.995989600300331e-07 6.222139129081946 -0.43878074919136034 LPSSPVYEDAASFK ddPTM_PC-9_AZD4547_30min_R2 2 LPSSPVYEDAASFK 14 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 0 ; 137.59 4.122e-05 0.0 11002.6 13424.2 13751.400000000001 14351.7 14678.099999999999 17974.7 15071.3 15462.3 15552.900000000001 13957.699999999999 False True 14501.197931703035 17763.310125461136 13569.047450994867 11043.137296554667 12640.299177448585 16850.7391675059 16412.616503023208 13072.956823306442 16374.994542125356 13469.045171393236 1.076631472177551 1.3188247495960919 1.0074246005065024 0.8198901374248169 0.9384703233674785 1.2510715461326842 1.2185434300778641 0.9705926928712035 1.2157502134526978 1.0 13.717359960466847 -6.754478470336568 24.999904810133252 1.1348131117686977 1.0349924297628519 0.10360490796220834 0.14521042230634454 448.1151726880201 1609391.8901120299 0.0528941638223063 0.051796602143448923 1.7600359134516242e-07 6.754478470336568 -0.09982068200584582 LPSSPVYEDAASFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LPSSPVYEDAASFK 14 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 0 127.17 0.00090964 0.0 6205.3 5611.7 5992.5 7961.9 7482.7 4463.8 6553.0 7161.6 5626.1 5658.2 False True 7255.734729738403 6168.792489566714 6135.383926682802 7515.820555828075 6016.518650011396 4229.710469929206 5932.252400388474 6973.615588342425 5708.371068964504 6683.986869713449 1.085539943624914 0.9229210963173508 0.9179227976170207 1.1244517235489855 0.9001392084226718 0.6328125043295513 0.8875320248261943 1.0433317306383927 0.8540368466057787 1.0 12.706493183977122 -1.5228796066195447 0.590330458713471 0.9003633440162421 10.443645160077528 0.13136637683263797 0.12373518982641564 378.2220222232904 3.0308923645182424 0.06129698063214137 4641.9548054207635 0.02999994050085445 1.5228796066195447 9.543281816061286 LPSTSDDCPAIGT(ph)PLR ddPTM_PC-9_AZD4547_30min_R2 3 LPSTSDDCPAIGTPLR 16 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 LPSTSDDCPAIGT(1)PLR;LPSTSDDCPAIGT(1)PLR;LPSTSDDCPAIGT(1)PLR 190.18 6.163199999999999e-08 24460200.0 13640.599999999999 19863.8 17443.8 18584.199999999997 20574.7 19892.6 20912.5 29898.4 26564.3 15357.000000000002 True False 17978.027057894353 26284.384892219663 17212.48381442356 14299.899813027796 17718.258050173477 18648.712577318558 22773.671987119407 25278.289276882828 27968.434665906698 14819.356104307011 1.2131449525441476 1.7736522901005478 1.1614866188026227 0.9649474452450574 1.1956159178214192 1.2584023520359704 1.5367517877852062 1.7057616470621213 1.887290815407163 1.0 13.855195143974303 -7.318989045379367 4.2171457308649964 1.599857219330363 1.2626477728387224 0.16421859538604877 0.2866278899443208 0.3565174622234931 13.138800918629686 0.1263126510455671 0.08446993375812509 4.7974554955998873e-08 7.318989045379367 -0.33720944649164064 LPSTSDDCPAIGT(ph)PLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LPSTSDDCPAIGTPLR 16 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 LPSTSDDCPAIGT(1)PLR;LPSTSDDCPAIGT(1)PLR;LPSTSDDCPAIGT(1)PLR;LPSTSDDCPAIGT(1)PLR 184.92 1.7369e-07 30619400.0 24096.4 39130.5 29281.8 28540.2 26528.1 13688.300000000001 23578.399999999998 9158.6 6092.4 15816.9 True False 28175.444594406144 43015.117435534754 29979.989163844883 26941.185122576822 21330.10923855925 12970.46145112503 21344.883259166716 8918.196454338824 6181.489824311576 18684.378763488497 1.5079679635623915 2.3021968233480377 1.6045483525751123 1.4419096007207426 1.1416012011189167 0.6941874608360464 1.1423919162288212 0.47730762511441066 0.3308373215164608 1.0 14.189544975928852 -6.240958615533433 0.9670199310583577 0.6589382194335622 1.9369660899903676 0.728423934462415 0.2901253807850698 0.28005413464091566 0.5536138229334863 0.13432839077139314 0.21728412719426884 5.741711730926789e-07 6.240958615533433 1.2780278705568053 LPSTSDDCPAIGT(ph)PLR ddPTM_PC-9_Lapatinib_30min_R1 4 LPSTSDDCPAIGTPLR 16 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 LPSTSDDCPAIGT(1)PLR;LPSTSDDCPAIGT(1)PLR;LPSTSDDCPAIGT(1)PLR;LPSTSDDCPAIGT(1)PLR 166.67 3.1103000000000004e-05 43062700.0 24026.800000000003 45312.8 47789.6 41576.8 54479.3 57048.1 53519.0 56882.8 47514.2 39681.6 True False 23684.173426024525 45207.88099561016 43860.523561190756 44634.49656813896 51274.93468442486 54608.285748616334 56289.95194952182 59525.78254887083 42162.65044929263 46540.511687591614 0.5088937050156901 0.9713662217354445 0.9424160150109526 0.9590461073516554 1.1017269218828876 1.1733494920550198 1.2094828764963825 1.2790100579135077 0.9059343982359742 1.0 15.506199452026548 -4.456731073230486 0.8270708178666395 1.1215736398784903 4.78378724687402e-18 0.6643221072040086 0.11841319013662313 2.3863097246641614 0.8727594111378173 0.04351201321833816 2.7754077230548906 3.493565794599356e-05 4.456731073230486 -1.1215736398784903 LPT(ph)PTSSVPAQK ddPTM_PC-9_Lapatinib_30min_R1 1 LPTPTSSVPAQK 12 0 Q9BTA9-2;Q9BTA9;Q9BTA9-3 Q9BTA9-2 WAC WW domain-containing adapter protein with coiled-coil 1 LPT(0.958)PT(0.03)S(0.01)S(0.002)VPAQK 96.23 0.010633 3660700.0 19591.0 20411.0 25158.0 21949.0 30200.0 25937.0 26230.0 28741.0 31006.0 35500.0 True False 19311.62874745061 20363.739583548097 23089.60635268837 23563.202679717575 28423.695375484454 24827.734972100072 27588.061055624305 30076.411784178985 27513.777772345264 41636.127699223354 0.46381903924775486 0.4890882199866042 0.5545570068255666 0.565931655554921 0.6826690411945933 0.5963026905732923 0.6625991075567508 0.7223633283442928 0.6608150011236151 1.0 15.345548278904761 -14.522878744271727 0.06930716910530504 2.4118982434574963 0.09401497638297195 0.9234385394917107 0.039873065477048525 78.46137751321878 0.39046408751021117 17.656909839886048 2.232613373897923 3.0000000069672328e-15 14.522878744271727 -2.3178832670745244 LPTTDGAHPQPIS(ph)PIPGGVSSSGLSR ddPTM_PC-9_AZD4547_30min_R2 2 LPTTDGAHPQPISPIPGGVSSSGLSR 26 0 Q96AP7 Q96AP7 ESAM Endothelial cell-selective adhesion molecule 1 LPTTDGAHPQPIS(0.996)PIPGGVSSSGLS(0.003)R;LPTTDGAHPQPIS(0.982)PIPGGVS(0.001)S(0.002)S(0.002)GLS(0.013)R 108.71 3.2546e-10 15224300.0 4449.2 9142.8 17521.0 25457.0 24803.0 19437.2 24267.0 40837.0 23090.6 22270.4 True False 5863.953050890987 12098.031302801364 17288.66009198197 19588.281956729308 21359.53158094421 18221.788811309547 26426.715988591845 34526.57999090466 24311.1219756058 21490.72007458219 0.2728597753142057 0.5629421099347025 0.8044709545321312 0.9114762971528831 0.993895574779128 0.8478910314811219 1.2296803409508659 1.606580881007353 1.131238129352371 1.0 14.391426202502425 -5.2706680297291095 0.5215074865211716 1.2586579939168177 1.6104288738719884e-14 0.7254427642621113 0.1804571982439822 1.503587198634291 0.450357398242551 0.12587598334217187 1.0879452973479384 5.362063715823265e-06 5.2706680297291095 -1.2586579939168014 down LPTTDGAHPQPIS(ph)PIPGGVSSSGLSR ddPTM_PC-9_Lapatinib_30min_R1 1 LPTTDGAHPQPISPIPGGVSSSGLSR 26 0 Q96AP7 Q96AP7 ESAM Endothelial cell-selective adhesion molecule 1 LPTTDGAHPQPIS(0.979)PIPGGVS(0.002)S(0.003)S(0.003)GLS(0.012)R 95.713 2.5043000000000005e-09 3449000.0 11628.0 12216.0 10071.0 7967.1 7097.5 8464.8 6440.5 5475.6 10677.0 4754.8 True False 11462.182587685953 12187.714602548802 9243.001255184228 8553.027111466492 6680.039004221886 8102.780236412562 6773.957576391474 5730.016365660566 9474.443826205586 5576.660844627247 2.055384558436798 2.1854860717038007 1.6574436769073493 1.5337183575914937 1.1978564216717023 1.4529806388027109 1.21469778513028 1.0274995244118292 1.698945675588933 1.0 12.4451858180303 -5.574926901140118 1.4089194133115714 1.2708618690223843 2.169906201366349 0.7286453303805053 0.20120797621168227 0.23081587145411894 0.8680041430564333 0.061558374680626825 0.1921482597156541 2.661172941007944e-06 5.574926901140118 0.8990443323439647 LPVDLAEELGHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LPVDLAEELGHR 12 0 K7ES20;K7ENC6;J3QRG6;P42771-2;P42771;P42771-4 K7ES20 CDKN2A Cyclin-dependent kinase inhibitor 2A 0 116.01 0.0006287999999999999 0.0 4176.7 4191.6 4242.0 3809.8 5078.5 3919.8 4182.0 3944.9 3732.6 4423.3 False True 4883.732816414738 4607.714346680655 4343.1453678745875 3596.349257538252 4083.404381317286 3714.2387875864733 3785.850684941947 3841.3505549670535 3787.1822136145684 5225.209275176467 0.9346482713364249 0.8818238857093512 0.8311907024485464 0.6882689416141702 0.7814814998351202 0.7108306274414311 0.7245357048046828 0.735157264076724 0.7247905326216177 1.0 12.35127310448012 -5.389402161533953 2.5137387641713915 0.7521543162671703 0.916132079264007 0.2953412894965297 0.08482735190635882 0.3012451009236914 3.633605021524135 0.021706873138710475 0.058720522727591255 4.079414530391681e-06 5.389402161533953 0.16397776299683664 LPVDLAEELGHR ddPTM_PC-9_Lapatinib_30min_R1 1 LPVDLAEELGHR 12 0 K7ES20;K7ENC6;J3QRG6;P42771-2;P42771;P42771-4 K7ES20 CDKN2A Cyclin-dependent kinase inhibitor 2A 0 144.7 5.6065e-06 0.0 5298.1 7096.1 7209.3 7323.9 8418.8 8109.8 4031.0 6130.3 7819.3 5618.0 False True 5222.548122447451 7079.669416433086 6616.579182702769 7862.524037814182 7923.622735997633 7762.962758867147 4239.70545616552 6415.136117760426 6938.608093120668 6589.063814485544 0.7926085206469067 1.0744575581236568 1.0041759146658642 1.1932687646049254 1.2025415080330784 1.1781586849714338 0.6434458028536403 0.9736035798677877 1.0530491566748341 1.0 12.68585778386439 LPYDVTPEQALAHEEVK ddPTM_PC-9_Lapatinib_30min_R1 1 LPYDVTPEQALAHEEVK 17 0 P46940;H0YLE8;A0A0J9YXZ5 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 0 120.39 7.2259e-05 2956000.0 17111.0 21893.0 17510.0 16624.0 14695.0 16692.0 19707.0 16780.0 16498.0 17669.0 False True 16866.99400222691 21842.308103601907 16070.395390554628 17846.58441603832 13830.668991481582 15978.12207095248 20727.332032908434 17559.6600584017 14639.821508358138 20723.063107537404 0.8139237869758761 1.0540096312140945 0.7754835907781169 0.8611943284362799 0.6674046650203503 0.7710309034932634 1.000205998763256 0.8473486746278782 0.7064506551173574 1.0 14.338949645288137 -5.288690017663363 24.968712445536962 0.8226621787989993 0.9339668047805973 0.11351317269653172 0.1167848042028476 1296.8234700597566 1188227.4970336591 0.030271584178554814 0.063038601514241 5.1441068671487585e-06 5.288690017663363 0.11130462598159807 LQAALDDEEAGGRPAMEPGNGS(ph)LDLGGDSAGR ddPTM_PC-9_AZD4547_30min_R2 9 LQAALDDEEAGGRPAMEPGNGSLDLGGDSAGR 32 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1X7SBS1 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 1 LQAALDDEEAGGRPAMEPGNGS(0.99)LDLGGDS(0.01)AGR;LQAALDDEEAGGRPAMEPGNGS(0.986)LDLGGDS(0.014)AGR;LQAALDDEEAGGRPAMEPGNGS(0.994)LDLGGDS(0.006)AGR;LQAALDDEEAGGRPAMEPGNGS(0.994)LDLGGDS(0.006)AGR;LQAALDDEEAGGRPAMEPGNGS(1)LDLGGDSAGR;LQAALDDEEAGGRPAMEPGNGS(0.967)LDLGGDS(0.033)AGR;LQAALDDEEAGGRPAMEPGNGS(0.999)LDLGGDS(0.001)AGR;LQAALDDEEAGGRPAMEPGNGS(0.999)LDLGGDS(0.001)AGR;LQAALDDEEAGGRPAMEPGNGS(1)LDLGGDSAGR 90.56 6.3136e-10 125825800.0 163600.3 161295.20000000004 244345.90000000002 338680.50000000006 252939.29999999996 241331.2 183339.6 275788.6 226876.70000000004 249352.1 True False 215621.79230236483 213430.71910045168 241105.7137132253 260602.94328656385 217823.04424512823 226240.72191364592 199656.4692241332 233171.80886156237 238868.9391840373 240622.35887587184 0.8961004011002823 0.8869945423922665 1.002008769424469 1.0830371063771311 0.9052485615332824 0.9402315020540345 0.8297502782238478 0.96903633540492 0.9927129810378965 1.0 17.876411179879376 -7.9937937711322515 24.97454399797765 0.9911959150326094 0.9373721693675954 0.12739029177538752 0.06506905171816237 369.65352906878826 1487526.7730899611 0.03895689938674406 0.018636296230344573 1.0143929655395355e-08 7.9937937711322515 -0.05382374566501402 LQAALDDEEAGGRPAMEPGNGS(ph)LDLGGDSAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LQAALDDEEAGGRPAMEPGNGSLDLGGDSAGR 32 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1X7SBS1 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 1 LQAALDDEEAGGRPAMEPGNGS(0.999)LDLGGDS(0.001)AGR;LQAALDDEEAGGRPAMEPGNGS(0.999)LDLGGDS(0.001)AGR;LQAALDDEEAGGRPAMEPGNGS(1)LDLGGDSAGR;LQAALDDEEAGGRPAMEPGNGS(0.998)LDLGGDS(0.002)AGR 78.544 7.008400000000001e-07 98697400.0 148021.80000000002 135392.5 188568.09999999998 187643.9 218270.4 172909.8 171668.3 174381.0 161470.59999999998 133984.8 True False 173078.96717618697 148833.37262213943 193064.27865250202 177130.82063273166 175501.88198717672 163842.10569769374 155406.6358531372 169803.68352194215 163831.80205263692 158275.18361690713 1.0935319310392415 0.9403456007505202 1.219801324759788 1.1191319863603073 1.1088401730240003 1.035172425351664 0.9818762000572812 1.0728383290518801 1.0351073257901198 1.0 17.27207554368666 -6.816043227037618 6.299905139609709 1.0261907917140167 1.0957503661420225 0.21990373124135443 0.06724150634370842 0.355628001907442 29.707211554315545 0.024560439760036457 0.021843478065013053 1.5274140211477956e-07 6.816043227037618 0.06955957442800575 LQAALDDEEAGGRPAMEPGNGS(ph)LDLGGDSAGR ddPTM_PC-9_Lapatinib_30min_R1 10 LQAALDDEEAGGRPAMEPGNGSLDLGGDSAGR 32 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1X7SBS1 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 1 LQAALDDEEAGGRPAMEPGNGS(0.999)LDLGGDS(0.001)AGR;LQAALDDEEAGGRPAMEPGNGS(0.994)LDLGGDS(0.006)AGR;LQAALDDEEAGGRPAMEPGNGS(1)LDLGGDSAGR;LQAALDDEEAGGRPAMEPGNGS(1)LDLGGDSAGR;LQAALDDEEAGGRPAMEPGNGS(1)LDLGGDSAGR;LQAALDDEEAGGRPAMEPGNGS(0.999)LDLGGDS(0.001)AGR;LQAALDDEEAGGRPAMEPGNGS(1)LDLGGDSAGR;LQAALDDEEAGGRPAMEPGNGS(1)LDLGGDSAGR;LQAALDDEEAGGRPAMEPGNGS(0.995)LDLGGDS(0.005)AGR;LQAALDDEEAGGRPAMEPGNGS(0.672)LDLGGDS(0.328)AGR 106.42 6.6571e-16 88216900.0 304628.0 240402.5 309874.0 252223.9 263318.3 272959.4 246584.30000000002 238452.4 289666.6 213289.99999999997 True False 300283.94885806623 239845.86278153528 284397.3558682307 270773.287000265 247830.43529769647 261285.56276143965 259351.22850775367 249531.7690172839 257041.297183475 250156.89230893995 1.2003824723214906 0.9587817491965375 1.1368759550986278 1.082413858363191 0.9907000083436824 1.044486763285962 1.0367542789405093 0.9975010750817769 1.0275203485740176 1.0 17.932473676369447 LQAALDDEEAGGRPAMEPGNGSLDLGGDSAGR ddPTM_PC-9_AZD4547_30min_R2 1 LQAALDDEEAGGRPAMEPGNGSLDLGGDSAGR 32 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1X7SBS1 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 54.824 0.0093779 4816100.0 2783.4 1666.0 7140.0 11910.0 6559.8 6851.9 2050.4 13791.0 7987.9 6906.8 False True 3668.4633016834423 2204.501919594335 7045.318934806878 9164.333507665717 5649.08500039019 6423.449609831244 2232.8816278488766 11659.917835653114 8410.124086378948 6664.995034266305 0.5504075071058584 0.33075822386370474 1.0570628933082828 1.3749947990283151 0.8475752752022945 0.9637590991151201 0.33501624777949685 1.7494263350095143 1.2618350116002375 1.0 12.70238808510131 -5.268994685813934 23.146179787767593 1.0728493795627863 0.44058283850333857 0.3442866534039478 0.3494981898426114 214.04535033204945 655748.8575376137 0.0944715982047028 0.20362795314836404 5.382763690224453e-06 5.268994685813934 -0.6322665410594477 LQAALDDEEAGGRPAMEPGNGSLDLGGDSAGR ddPTM_PC-9_Lapatinib_30min_R1 2 LQAALDDEEAGGRPAMEPGNGSLDLGGDSAGR 32 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1X7SBS1 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 ; 88.10799999999999 3.0244e-09 11820300.0 16570.800000000003 12786.2 11126.2 11864.0 13233.8 13239.5 12439.6 13069.9 14534.8 10847.3 False True 16334.497353287454 12756.59433948178 10211.446784374019 12736.518137143805 12455.413902651862 12673.277447781888 13083.66162056974 13677.17526801575 12897.737765770618 12722.241351881283 1.2839323592043013 1.0027002307730484 0.8026452652436133 1.0011221910406858 0.9790266949156751 0.9961513146351249 1.028408537355331 1.0750601949548189 1.0137944572057174 1.0 13.635065240610968 -7.3320948196844276 4.989504622166645 1.0363571235565108 0.999200873116133 0.0 0.1111269399480679 1.2565194816651195 59.68283762712156 0.04964553053908566 0.03315116603732366 4.654844530247124e-08 7.3320948196844276 -0.037156250440377736 LQADPKPIS(ph)PQQK ddPTM_PC-9_AZD4547_30min_R2 2 LQADPKPISPQQK 13 1 O75128-3;O75128;O75128-7;H7C1N2;J3KR05;O75128-2;O75128-6 O75128-3 COBL Protein cordon-bleu 1 LQADPKPIS(1)PQQK;LQADPKPIS(1)PQQK 109.14 0.0003868 40760000.0 179456.0 152949.0 190986.0 220392.0 190374.0 193469.0 187347.0 203930.0 180498.0 206821.0 True False 236519.27508331608 202386.7731692882 188453.4008519645 169584.02942245675 163943.85619443885 181371.35284584484 204020.5200607701 172417.3043452059 190038.75578602977 199580.25974141303 1.1850835117148522 1.014062079243265 0.9442487002278428 0.8497034207800861 0.8214432449724907 0.9087639883866239 1.022247993489487 0.8638995889102413 0.9521921458176988 1.0 17.606609506827695 -4.80627302440947 1.814768143176421 0.9116437654703269 1.2648404762723684 0.6428050132427505 0.06049224921771686 0.5164112490805827 1.8367669603749301 0.017229041965862068 0.31145749447844356 1.5621652600444467e-05 4.80627302440947 0.3531967108020415 LQADPKPIS(ph)PQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LQADPKPISPQQK 13 1 O75128-3;O75128;O75128-7;H7C1N2;J3KR05;O75128-2;O75128-6 O75128-3 COBL Protein cordon-bleu 1 LQADPKPIS(1)PQQK;LQADPKPIS(1)PQQK 66.335 0.017777 20455400.0 154921.0 136234.0 128684.0 170477.0 187958.0 184022.0 178881.0 182811.0 161858.0 152194.0 True False 181146.06547077573 149758.41118085978 131752.31459678774 160925.72638389128 151128.97916779248 174371.5623677837 161936.09669371165 178012.4049542656 164224.86704474775 179785.5674329586 1.0075673373410492 0.8329834998390745 0.7328303182396312 0.8950981365281165 0.8406068480672007 0.9698863198949841 0.9007179998144014 0.9901373480418321 0.9134485564642814 1.0 17.455917685341305 -6.7597156723228435 24.998828184589996 0.9508391331125498 0.8548983450777997 0.3042263321737142 0.0698162451763557 58.85709742151354 853603.4571174749 0.02385485697157916 0.02268884959422386 1.738938919771317e-07 6.7597156723228435 -0.09594078803475004 LQADPKPIS(ph)PQQK ddPTM_PC-9_Lapatinib_30min_R1 2 LQADPKPISPQQK 13 1 O75128-3;O75128;O75128-7;H7C1N2;J3KR05;O75128-2;O75128-6 O75128-3 COBL Protein cordon-bleu 1 LQADPKPIS(1)PQQK;LQADPKPIS(1)PQQK 78.32600000000001 0.0071357 36953000.0 143779.0 108376.0 111984.0 118161.0 126600.0 126831.0 129833.0 116846.0 127846.0 107909.0 True False 141728.68509416046 108125.06203060177 102777.10779074056 126850.9541135407 119153.63690517661 121406.7337875016 136555.1174622519 122275.09172729454 113446.63720193674 126560.92687029562 1.1198455052356666 0.8543320968359562 0.8120761307008315 1.0022916017638075 0.94147253699627 0.9592750052464752 1.078967425722148 0.9661361902999228 0.8963796331722594 1.0 16.949472544991337 LQAEAQQLR ddPTM_PC-9_Lapatinib_30min_R1 1 LQAEAQQLR 9 0 Q16543;K7EKQ2;K7EQA9 Q16543 CDC37 Hsp90 co-chaperone Cdc37;Hsp90 co-chaperone Cdc37, N-terminally processed 0 91.265 0.036557 4351000.0 25316.0 30196.0 22053.0 24666.0 26707.0 24471.0 23121.0 19919.0 23543.0 22631.0 False True 24954.989197614184 30126.083017236706 20239.887467041775 26480.019923363892 25136.146767982238 23424.432374687163 24318.09224807814 20844.509457884604 20891.33942121928 26542.738196088 0.9401814165989918 1.1350028318358214 0.7625395434908381 0.997637083549528 0.947006544022912 0.8825175534504414 0.9161862679134687 0.785318730264113 0.7870830532585499 1.0 14.696029588921682 -6.9650166624558105 1.2857094938429119 0.8480104855210361 0.962418893149931 0.1288426142278024 0.10292072533696776 0.7965396914753485 2.705199463715505 0.05484018523111162 0.041086850974812954 1.0838853280959955e-07 6.9650166624558105 0.11440840762889493 LQAEEAER ddPTM_PC-9_Lapatinib_30min_R1 1 LQAEEAER 8 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 98.58200000000001 0.025166 5712800.0 41928.0 30227.0 32084.0 36993.0 39287.0 31889.0 31288.0 32342.0 38009.0 20304.0 False True 41330.09903134649 30157.011238641346 29446.17736782153 39713.58862503041 36976.215901213836 30525.18180688974 32907.93954664025 33844.72739027577 33728.026167486016 23813.519346620604 1.7355729083870874 1.2663819572272064 1.2365319438598756 1.6676908627815317 1.5527404984959168 1.2818425266159408 1.3819015605230245 1.4212400484634249 1.4163394194933387 1.0 14.539493228579099 -12.707343302593044 0.28516862339728677 2.6999416900106338e-17 1.4646436979542434 0.42366248230938464 0.15687847952170475 77.6418258761095 1.8921162801930587 46.39419844702169 0.18151771041342482 1.9618088863189798e-13 12.707343302593044 1.4646436979542434 LQAEEAERR ddPTM_PC-9_AZD4547_30min_R2 1 LQAEEAERR 9 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 99.973 0.0062996 0.0 4352.4 5198.9 8406.6 14568.0 11676.0 10030.0 7448.3 9396.7 5886.1 8825.4 False True 5736.372664456065 6879.3427549693815 8295.122991225138 11209.572673356344 10054.98894243054 9402.822514427738 8111.184270730975 7944.655929684696 6197.227229288689 8516.425432242693 0.6735657712376005 0.8077734971910384 0.9740146329257207 1.3162297682919353 1.1806583668733757 1.1040808833749893 0.9524165197316824 0.9328627360026766 0.727679385981159 1.0 13.0560323051024 -5.1680782362062665 2.8188605008979457 1.0395411289589114 0.6972555601355086 0.3795327646697667 0.14896642575429636 0.31546793499709735 4.698221054888225 0.04430407416666422 0.16098957440884487 6.790812881442865e-06 5.1680782362062665 -0.3422855688234028 LQAEEAERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQAEEAERR 9 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 70.908 0.023036 2010300.0 7241.9 3646.1 5881.7 8717.3 7646.1 9462.1 8255.7 7138.8 8040.7 5631.1 False True 8467.810635955151 4008.060711764564 6021.942034471462 8228.89794286792 6147.901592988113 8965.890818924936 7473.6603299079925 6951.414064183827 8158.280025990096 6651.973854236927 1.2729771375396552 0.6025370513462945 0.9052864858504862 1.2370610773863133 0.9242221523574167 1.3478541881541186 1.123525211264578 1.0450152415671587 1.2264449928337795 1.0 12.699566782746551 -5.739397177625507 21.213507717145482 1.1313742335439407 0.8944925391827542 0.18537855833701944 0.19062201101808565 58.73852922789197 56526.659544377006 0.048872637013819935 0.08446221765978647 1.82222844785098e-06 5.739397177625507 -0.23688169436118656 LQAGDAPSMGNGYPPR ddPTM_PC-9_AZD4547_30min_R2 1 LQAGDAPSMGNGYPPR 16 0 Q8IVL1-4;Q8IVL1-11;A0A0A0MTL4;A0A0A0MTE8;Q8IVL1-8;Q8IVL1-9;Q8IVL1-10;Q8IVL1-13;Q8IVL1-12;Q8IVL1-3;Q8IVL1-2;Q8IVL1 Q8IVL1-4 NAV2 Neuron navigator 2 0 88.134 0.018764 10026000.0 9926.3 10532.0 16069.0 23759.0 10533.0 16575.0 10235.0 18696.0 12591.0 15413.0 False True 13082.65692013377 13936.263035514716 15855.91456070192 18281.72962289082 9070.674762814391 15538.562629774655 11145.895172177748 15806.962791340042 13256.534554964048 14873.395561352077 0.879601222610426 0.9369926980041825 1.0660588226338092 1.2291564187531703 0.6098590416289456 1.0447219376153074 0.7493847068210779 1.0627675923858169 0.8912917363275553 1.0 13.860446428439005 -4.810567138409483 4.754911049297316 0.9548151488291777 0.8773330786839781 0.018818223936074463 0.16575302403536465 1.0012119134355328 44.70971904059928 0.04050987923109258 0.22203997772193668 1.546795363428356e-05 4.810567138409483 -0.07748207014519959 LQALAEEPSQPHT(ph)RSPAK ddPTM_PC-9_AZD4547_30min_R2 2 LQALAEEPSQPHTRSPAK 18 1 Q5VV41 Q5VV41 ARHGEF16 Rho guanine nucleotide exchange factor 16 1 LQALAEEPS(0.094)QPHT(0.757)RS(0.149)PAK;LQALAEEPS(0.098)QPHT(0.451)RS(0.451)PAK 60.306999999999995 0.016544999999999997 11339100.0 47021.0 28852.0 48418.0 87317.0 82587.0 50999.0 45332.0 50543.0 38327.0 62847.0 True False 61972.69990244202 38177.844768388786 47775.9456842408 67187.41468420213 71121.22060538807 47810.02446792621 49366.46018027963 42732.74071259627 40352.88697387873 60646.745659138025 1.0218635679275596 0.6295118452516058 0.7877742682643368 1.1078486397576155 1.1727128938644342 0.7883361909745338 0.8140001519247435 0.7046172098462379 0.6653759659369045 1.0 15.888142611088318 -6.957836479963421 24.99984892378057 0.7756371437170603 0.9322659424691032 0.16144400910260592 0.16679970380142486 281.9450035689396 167171.6847585314 0.06345197161225974 0.055959340710461096 1.1019541378893241e-07 6.957836479963421 0.15662879875204294 LQAQEHGAER ddPTM_PC-9_Lapatinib_30min_R1 2 LQAQEHGAER 10 0 B4DHR0;Q9H5N1-2;Q9H5N1 B4DHR0 RABEP2 Rab GTPase-binding effector protein 2 0 ; 115.23 0.00087559 0.0 14105.8 11902.400000000001 16837.0 10575.3 15442.400000000001 17742.5 12149.0 13995.7 16736.8 10875.3 False True 13904.648705313082 11874.840724081274 15452.726852699516 11353.042840166623 14534.108392926531 16983.69463478758 12778.015774486448 14645.991315814814 14851.725337682647 12755.08111457363 1.0901262469766646 0.9309890401648159 1.2114957728527203 0.8900800189498541 1.1394759674495705 1.3315238438885695 1.001798080287127 1.1482476029949098 1.1643771767718079 1.0 13.63878445318376 -6.4591303112027445 24.99974926179762 1.1421612480926213 1.0337570276013248 0.14082584368384576 0.11927837851737912 389.4838734684571 152740.26531542742 0.03551071412890279 0.040265319834245555 3.474318979459911e-07 6.4591303112027445 -0.1084042204912965 LQAVEVVITHLAPGTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQAVEVVITHLAPGTK 16 0 Q9Y2V2 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 0 115.56 0.00072429 0.0 2392.2 3055.9 3725.6 5417.6 6113.4 4166.7 5265.7 4168.7 2708.1 3453.4 False True 2797.152211896315 3359.2695562604763 3814.4324334166795 5114.069436096184 4915.523155409097 3948.1909169438636 4766.894775633385 4059.276042102751 2747.7008392781445 4079.474082900642 0.68566490558691 0.8234565260117853 0.9350304367430841 1.253609983093681 1.2049404054343191 0.9678186052199573 1.1685071846917983 0.9950488615965102 0.6735429085811075 1.0 11.994167459678343 -5.225493579139911 2.4673459113076714 1.0476361885893504 0.7141412994854727 0.34482217368770596 0.155274485858839 0.3491149512677603 4.001787609262883 0.04440631399870371 0.15951476065453454 5.949855533035162e-06 5.225493579139911 -0.3334948891038777 LQAVTDDHIR ddPTM_PC-9_AZD4547_30min_R2 2 LQAVTDDHIR 10 0 A0A2R8YEP4;P30043 A0A2R8YEP4 BLVRB Flavin reductase (NADPH) 0 ; 172.61 0.00061177 26903000.0 259960.0 262360.0 355730.0 463730.0 441430.0 341900.0 302170.0 379180.0 320940.0 329760.0 False True 342621.87249609415 347162.7392705696 351012.78777014697 356824.2130570795 380145.06413644366 320520.93895143055 329062.5446191444 320586.4436895758 337904.23318800377 318215.2027711328 1.0766986288286016 1.090968427175544 1.1030673101517494 1.1213298734621273 1.1946162874243695 1.007245839168646 1.0340880691857242 1.0074516896043728 1.0618733179477655 1.0 18.279643236688386 -6.790733624477281 24.99895263287828 1.023344739734343 1.1153004453383306 0.6686362050282275 0.03348997618259796 136.04953955854435 116100.20397835007 0.012168268970322185 0.010732981710621961 1.6190727951922246e-07 6.790733624477281 0.09195570560398769 LQAVTDDHIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LQAVTDDHIR 10 0 A0A2R8YEP4;P30043 A0A2R8YEP4 BLVRB Flavin reductase (NADPH) 0 ;;;; 180.66 0.0001229 36093900.0 259074.0 254605.0 284618.0 318168.0 345367.0 312854.0 313410.0 279171.0 267913.0 239208.0 False True 302930.1112552567 279880.5017741735 291404.3725397762 300342.0784745741 277694.81558775326 296447.3854920092 283721.5359080955 271843.057056125 271830.7207834 282574.5168305144 1.0720362000546262 0.9904661783144559 1.0312478839504053 1.0628774379351287 0.9827312763461683 1.0490945497035589 1.0040591738081925 0.9620225493269585 0.9619788926205315 1.0 18.108271840675044 -7.560026494170706 4.378399542042321 0.9721638179450495 1.0287582539592686 0.44365978700518727 0.028368447166815452 0.18528953545085394 8.052100758880362 0.01322102966164858 0.00755643363816709 2.7540606865138368e-08 7.560026494170706 0.056594436014219096 LQAVTDDHIR ddPTM_PC-9_Lapatinib_30min_R1 4 LQAVTDDHIR 10 0 A0A2R8YEP4;P30043 A0A2R8YEP4 BLVRB Flavin reductase (NADPH) 0 ;;; 181.87 0.00043391 53724800.0 272253.0 270958.0 292449.0 242170.0 270347.0 277788.0 251964.0 232983.0 276471.0 223634.0 False True 268370.62229491386 270330.6133986092 268404.9721057864 259979.98965543776 254445.72098265224 265907.6547954558 265009.4630506793 243808.24072625706 245331.92461130314 262288.83892642625 1.02318735098825 1.0306599949319184 1.0233183127593002 0.9911973026361365 0.9700974011098732 1.0137970638927745 1.0103726263587456 0.9295410423264212 0.9353502254059707 1.0 18.00079689291244 -6.304553383148333 0.5505231095412295 0.9608834336260171 1.0354312430561154 0.40420039087321147 0.026638019518924583 1.1536622879437586 0.7146328247023636 0.02236932250768723 0.04443601916481868 4.959599606268483e-07 6.304553383148333 0.07454780943009831 LQDAEIAR ddPTM_PC-9_AZD4547_30min_R2 3 LQDAEIAR 8 0 R4GN98;P06703 R4GN98 S100A6 Protein S100;Protein S100-A6 0 ;; 138.06 0.014098 76447000.0 413514.0 420806.0 538869.0 757714.0 614751.0 558677.0 457233.0 557752.0 477308.0 458834.0 False True 545002.8503744804 556823.3101901638 531723.2449692497 583034.7438646022 529403.435024677 523742.8388726754 497925.8512223116 471564.24426591187 502537.5264364048 442770.36131820077 1.2308928012975315 1.2575893935908637 1.200900718345784 1.3167881023671302 1.195661411139976 1.1828769146006208 1.1245690649661007 1.0650311887678907 1.1349845661310014 1.0 18.75619912697551 -7.467593064959225 0.66947840460778 1.0294918044875179 1.255769372735243 0.7888467363129158 0.040558632252376076 0.31940062770010297 0.28031643862482003 0.03600586469543168 0.021398466437218697 3.407273025271749e-08 7.467593064959225 0.22627756824772516 LQDAEIAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LQDAEIAR 8 0 R4GN98;P06703 R4GN98 S100A6 Protein S100;Protein S100-A6 0 ;;; 104.01 0.017807 66754000.0 361997.0 434027.0 467364.0 497714.0 505777.0 447202.0 448620.0 434945.0 373017.0 337828.0 False True 423275.94233334553 477114.33217548556 478507.73024783947 469828.6981905587 406673.62760057277 423749.9398658723 406123.46587246715 423528.1546123198 378471.6679461671 399073.54215502425 1.0606464664322939 1.195554908498909 1.1990464906890725 1.1772985391450703 1.0190443230200317 1.0618342112523769 1.01766572566894 1.061278460920358 0.9483757452383197 1.0 18.606295108417463 -6.263756712671825 24.967649435528525 1.023268685193272 1.1637314762442155 0.6783327329649148 0.04711913871231833 119.73007475487042 1290005.6061638256 0.014200488017425366 0.01689085289231544 5.44807763112944e-07 6.263756712671825 0.1404627910509435 LQDAEIAR ddPTM_PC-9_Lapatinib_30min_R1 4 LQDAEIAR 8 0 R4GN98;P06703 R4GN98 S100A6 Protein S100;Protein S100-A6 0 ;;; 126.24 0.016156999999999998 259717000.0 1075065.0 1033581.0 1136608.0 1134691.0 1065365.0 1141811.0 1093771.0 977610.0 1087852.0 968720.0 False True 1059734.3759572222 1031187.806697527 1043160.4776737607 1218139.961358212 1002702.3252881778 1092978.405221442 1150401.1105173947 1023033.3295407661 965326.6521705919 1136161.9612617388 0.9327317865670827 0.9076063465039481 0.9181441671531606 1.0721534454519446 0.8825346732913409 0.9619917252005689 1.0125326755701651 0.9004291328365366 0.8496382426837898 1.0 20.11573707674954 -10.261470184035833 10.48187987922881 0.9999999699517642 0.9402552574171075 0.0834661117393608 0.061509604870832735 0.0 0.0 0.06001595440040746 0.014556007012654885 5.47683700235488e-11 10.261470184035833 -0.05974471253465674 LQDEIQNMK ddPTM_PC-9_Lapatinib_30min_R1 1 LQDEIQNMK 9 0 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 0 111.46 0.029824 6450200.0 27828.0 23787.0 30798.0 25232.0 21035.0 23537.0 26668.0 19918.0 19386.0 23012.0 False True 27431.16761696982 23731.922662968933 28265.90732371797 27087.64545148454 19797.76265640117 22530.37737742683 28048.738552473842 20843.462994233923 17202.544536369904 26989.593538437413 1.0163609013934773 0.8792990020087169 1.0472891073169697 1.0036329525640126 0.7335331904204504 0.8347801661162492 1.039242718217599 0.7722777656710378 0.6373769398146283 1.0 14.720115629622232 -6.239947654084287 24.762684543149998 0.8348966454131569 0.9833095877832128 0.2813003408200625 0.1177468369711367 1029.637453037259 1186343.9516609807 0.03557459623085313 0.0458802933162715 5.755092998252794e-07 6.239947654084287 0.14841294237005587 LQDGTPQAALS(ph)PLTPAR ddPTM_PC-9_AZD4547_30min_R2 1 LQDGTPQAALSPLTPAR 17 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6 A0A087WVP4 SMTN Smoothelin 1 LQDGTPQAALS(0.83)PLT(0.17)PAR 144.4 1.3295999999999999e-08 0.0 11576.0 13276.0 12550.0 22102.0 21696.0 12885.0 13977.0 15230.0 12486.0 14681.0 True False 15256.92720424212 17567.207373670102 12383.578799975676 17006.725372496032 18683.88490022036 12079.298913100838 15220.92592296321 12876.553450583482 13145.984469325793 14167.022658548622 1.0769325052950227 1.24000700761707 0.8741130086711066 1.2004445663982817 1.318829322895604 0.8526349681393348 1.074391302238699 0.9089103448855961 0.9279285271272777 1.0 13.790248972874153 -6.77813424009326 24.99672755930683 0.9546810866896488 1.1358635994735093 0.3732135955640472 0.12251032418463265 286.34564356604056 428734.3020182634 0.04334503945457108 0.0383274432898641 1.6667319473468797e-07 6.77813424009326 0.18118251278386055 LQDGTPQAALS(ph)PLTPAR ddPTM_PC-9_Lapatinib_30min_R1 1 LQDGTPQAALSPLTPAR 17 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6 A0A087WVP4 SMTN Smoothelin 1 LQDGTPQAALS(0.615)PLT(0.385)PAR 116.61 0.0012749 0.0 17359.0 12315.0 18496.0 15409.0 17901.0 15739.0 14539.0 12511.0 16356.0 12669.0 True False 17111.457476749267 12286.485374131342 16975.330276624696 16542.22926291713 16848.0983747201 15065.879659400984 15291.75828012665 13092.306733650985 14513.815043684432 14858.81976961862 1.1516027344067088 0.8268816477102137 1.142441360742099 1.1132936208527495 1.1338786415034723 1.0139351505027157 1.029136803408387 0.8811135027305755 0.9767811487531729 1.0 13.859031907260452 -7.586252618930539 6.075961561896235 0.946687543728889 1.0588607028219208 0.21665792589127364 0.09386647350187625 0.3171236395988896 22.31218174936873 0.04497207163004458 0.025699072678232623 2.5926708275122003e-08 7.586252618930539 0.11217315909303183 LQDGTPQAALSPLT(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 1 LQDGTPQAALSPLTPAR 17 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6 A0A087WVP4 SMTN Smoothelin 1 LQDGTPQAALS(0.471)PLT(0.529)PAR 108.97 0.0011957 6265300.0 8171.9 9393.1 12337.0 15304.0 17374.0 13930.0 9286.0 14014.0 9180.2 12840.0 True False 10770.394213920712 12429.235882918096 12173.403319147395 11775.899244442991 14961.919997069896 13058.954897904123 10112.43601063435 11848.458309683328 9665.446630250248 12390.475508191837 0.8692478514484755 1.0031282394852912 0.982480721671987 0.950399299579542 1.2075339632589543 1.0539510682435334 0.816145918205368 0.9562553351443083 0.7800706779864934 1.0 13.596943934271431 -7.25331888547038 24.906670841725955 0.884472593242152 1.0156257131840045 0.266821716463185 0.09964988540356237 780.2793517267706 2393227.9057460553 0.03922553141656092 0.029838522095106602 5.5806028240172704e-08 7.25331888547038 0.13115311994185253 LQDSSDPDTGSEEEGS(ph)SRLSPPHSPR ddPTM_PC-9_Lapatinib_30min_R1 1 LQDSSDPDTGSEEEGSSRLSPPHSPR 26 1 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF0 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 LQDS(0.001)S(0.005)DPDT(0.121)GS(0.02)EEEGS(0.29)S(0.29)RLS(0.239)PPHS(0.034)PR 60.521 0.00097523 4292400.0 22981.0 21699.0 21013.0 20975.0 18217.0 15456.0 11887.0 14641.0 15684.0 9777.4 True False 22653.28672580075 21648.75729868259 19285.392252525686 22517.57147054882 17145.51187600001 14794.982909695762 12502.450696462307 15321.274309598291 13917.502760158133 11467.410562433433 1.9754491742025522 1.8878505466266862 1.681756500085861 1.9636143092595872 1.4951511313432613 1.2901764377533722 1.090259272430657 1.3360709661682377 1.2136569702798519 1.0 13.485252035028017 -6.54389135913515 2.192756886271704 1.19059196502917 1.8681891361201728 0.8854051269203191 0.11701291443630597 0.09936391087267923 0.9638070608549327 0.04189179818423186 0.044507766160772254 2.858305472886182e-07 6.54389135913515 0.6775971710910027 LQEAGILSAEELQR ddPTM_PC-9_Lapatinib_30min_R1 4 LQEAGILSAEELQR 14 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ;;; 163.33 0.0021086 11361900.0 42167.8 44488.0 49129.0 43515.4 45947.4 60243.0 41827.1 41918.9 48469.0 41102.1 False True 41566.47943937255 44384.99076933458 45089.803263424255 46715.667679119 43244.86426806405 57666.54732329198 43992.702576427866 43866.605126468094 43009.91081880291 48206.54321989433 0.8622580393239752 0.9207254410852957 0.9353461221591215 0.9690731705450295 0.8970745749348265 1.1962390055691363 0.9125877865947571 0.9099720120227333 0.8922006836833962 1.0 15.556941360656406 -4.791923682749237 1.071036344168694 0.9691367685879655 0.8133239438182976 0.1325825136335943 0.08403336697995273 3.9399989842170062 3.72126248531846 0.02796801542408549 0.7010315487831603 1.614642268081524e-05 4.791923682749237 -0.15581282476966785 LQEDPNYS(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 2 LQEDPNYSPQR 11 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710;P46379-4;H0Y4L1 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 LQEDPNYS(1)PQR;LQEDPNYS(1)PQR 123.95 0.00053626 39177000.0 59949.0 83927.0 80761.0 77328.0 67521.0 78684.0 75446.0 92181.0 67760.0 69036.0 True False 79011.53498333707 111054.76146806344 79690.05637169997 59501.22430569053 58146.87464729812 73763.87704139917 82160.54784173156 77936.54455864971 71341.65526521826 66619.07065292307 1.1860197719505452 1.6670115686039018 1.1962048643229368 0.8931560245816754 0.8728262654733805 1.1072486649611137 1.2332887120232827 1.1698833951720709 1.0708893799629728 1.0 16.02364760786716 -5.513453620711022 23.867343709742624 1.0582494034740142 1.4277888953245585 0.49737037165023834 0.15045662417347308 192.2159249371083 486748.5797331273 0.04155084628941923 0.07760212293367716 3.0658180675826354e-06 5.513453620711022 0.36953949185054435 LQEDPNYS(ph)PQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LQEDPNYSPQR 11 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710;P46379-4;H0Y4L1 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 LQEDPNYS(1)PQR;LQEDPNYS(1)PQR;LQEDPNYS(1)PQR 122.66 0.00064714 25642700.0 93108.0 148982.0 130263.0 110610.0 121052.0 91420.0 114164.0 70606.0 80550.0 72617.0 True False 108869.3454331753 163771.94837226256 133368.96394517858 104412.88030245848 97332.72957905284 86625.7742642878 103349.55944421655 68752.66731324066 81727.89136437168 85781.88726414446 1.2691414109127563 1.9091670001146823 1.554745042324626 1.2171902907771708 1.1346536277447519 1.0098375895781448 1.2047946570116452 0.8014823350940454 0.9527406538948078 1.0 16.38838543621621 -5.946080919490187 1.8896764351931592 1.007905252167502 1.6252188867628816 0.6710926529935226 0.1752670657958153 0.19002792839189442 1.3740024883957624 0.05576242429354912 0.0943907158861944 1.1321893895122176e-06 5.946080919490187 0.6173136345953796 LQEDPNYS(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 2 LQEDPNYSPQR 11 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710;P46379-4;H0Y4L1 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 LQEDPNYS(1)PQR;LQEDPNYS(1)PQR 142.1 0.00013769 41346000.0 45237.0 101213.0 97400.0 83996.0 103592.0 85996.0 88065.0 97902.0 85435.0 80809.0 True False 44591.91208455018 100978.64751700802 89392.14797487251 90173.34604244187 97498.92222970819 82318.15154646724 92624.57479464568 102450.88432882274 75812.41062956574 94776.72797877593 0.4704943189696946 1.0654371560455318 0.9431866860279327 0.9514291953889258 1.0287221801067226 0.8685481478628526 0.9772923878041855 1.080970893527421 0.7999053380123334 1.0 16.532245234545314 -4.754601480984385 24.999815028434327 0.9686445525468911 0.4704934691833983 0.7714710571976242 0.08129578117487936 103.13849193225906 377047.73730205867 0.018926187816267127 0.1816309118540859 1.7595374671015923e-05 4.754601480984385 -0.4981510833634928 LQEDPNYS(ph)PQRFPNAQR ddPTM_PC-9_AZD4547_30min_R2 3 LQEDPNYSPQRFPNAQR 17 1 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710;P46379-4;H0Y4L1 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 LQEDPNY(0.169)S(0.831)PQRFPNAQR;LQEDPNY(0.001)S(0.999)PQRFPNAQR;LQEDPNY(0.185)S(0.815)PQRFPNAQR 122.97 0.00024627 61681000.0 143314.0 134350.0 210562.0 300317.0 230031.0 203894.0 172684.0 221043.0 159197.0 204142.0 True False 188884.8708836177 177776.0101425563 207769.81030123334 231083.55550139738 198095.1662740872 191144.47594782893 188052.54146676566 186885.88341282512 167611.82841288316 196995.05071598873 0.958830540143551 0.9024389673568963 1.0546955852245181 1.1730424427492578 1.0055844832349852 0.9703009047846858 0.9546054115739403 0.9486831406859141 0.850842839978412 1.0 17.587799858447426 -7.020512227839294 2.176555172494334 0.9325690236675618 1.0223881365700387 0.21096462404171246 0.07364039555185233 0.5418052994056707 5.131041365536677 0.03544572169463819 0.027406043383722885 9.538668857303584e-08 7.020512227839294 0.0898191129024769 LQEDPNYS(ph)PQRFPNAQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LQEDPNYSPQRFPNAQR 17 1 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710;P46379-4;H0Y4L1 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 LQEDPNY(0.05)S(0.95)PQRFPNAQR;LQEDPNY(0.01)S(0.99)PQRFPNAQR;LQEDPNY(0.028)S(0.972)PQRFPNAQR 106.28 0.0032194000000000003 32057300.0 104215.0 98047.0 122141.0 148097.0 158734.0 128347.0 123654.0 115688.0 131361.0 99887.0 True False 121856.54115992606 107780.45818995104 125053.30466232225 139799.60522695235 127631.2121815535 121616.2573780196 111940.59794256595 112651.3125815684 133281.90611440365 117995.72239494289 1.032719989221818 0.9134268260098414 1.0598121874601265 1.1847853667019368 1.081659653342006 1.0306836121648413 0.9486835257289254 0.9547067494914244 1.129548626078973 1.0 16.84837503409628 -10.025716505097957 15.151796677177087 0.9999948973470568 1.0347599273381993 0.018647903458441806 0.07929683934178884 0.0 0.0 0.08272369107522097 0.02006344212024124 9.425046355822023e-11 10.025716505097957 0.034765029991142504 LQEDPNYS(ph)PQRFPNAQR ddPTM_PC-9_Lapatinib_30min_R1 3 LQEDPNYSPQRFPNAQR 17 1 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710;P46379-4;H0Y4L1 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 LQEDPNY(0.419)S(0.581)PQRFPNAQR;LQEDPNY(0.134)S(0.866)PQRFPNAQR;LQEDPNY(0.254)S(0.746)PQRFPNAQR 82.705 0.011945 49379000.0 173188.0 133749.0 152449.0 122103.0 118954.0 132526.0 103699.0 106847.0 148981.0 93945.0 True False 170718.3073612104 133439.31240801388 139915.23169015808 131082.86194366738 111957.35959256206 126858.17191319476 109068.02681689622 111811.50168415053 132201.19094052038 110183.26807615632 1.5494031928987035 1.2110669318301892 1.2698410033858467 1.1896802866027327 1.0161012787819974 1.151337894838199 0.9898783065820005 1.014777503303576 1.1998300036730236 1.0 16.749545633951286 -1.5228787452855104 0.5001268207971818 1.0541075808248401 15.796095519457237 0.7574085097925097 0.0802064493809089 51.44935117519023 0.5465318889670071 0.04318263240875816 796.9041403824693 0.029999999999642674 1.5228787452855104 14.741987938632397 LQEEERER ddPTM_PC-9_AZD4547_30min_R2 2 LQEEERER 8 1 H3BNC9;P08708;H0YN88;A0A075B716 H3BNC9 RPS17 40S ribosomal protein S17 0 ; 120.87 0.0044034 41068000.0 63487.0 43635.0 87663.0 144731.0 107008.0 74459.0 45267.0 78809.0 64308.0 79388.0 False True 83674.54538836543 57739.16042106769 86500.53134201343 111365.50402165954 92151.78629253231 69803.0669592997 49295.6753062013 66630.87990065874 67707.18959261599 76608.65028382652 1.0922336456569925 0.7536898275475489 1.1291222469204012 1.4536935921604512 1.2028900907550284 0.9111642967300313 0.6434740087909957 0.8697566091270209 0.8838060629154593 1.0 16.225219683148467 -6.900116579567246 5.361361239458903 0.8305824029303955 1.1225131308133 0.35349727317283486 0.1794239574619337 0.2535073835316126 11.28919261208432 0.07091761083623015 0.06239917287048355 1.2585875182928751e-07 6.900116579567246 0.29193072788290453 LQEEERER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LQEEERER 8 1 H3BNC9;P08708;H0YN88;A0A075B716 H3BNC9 RPS17 40S ribosomal protein S17 0 ;; 111.74 0.0048495 24763000.0 88163.0 37555.8 72140.0 128035.0 111255.0 127577.0 91605.0 148155.0 117514.0 89187.0 False True 103087.25460137754 41284.091626364476 73860.0911924735 120861.61404507073 89455.38140069995 120886.63753352697 82927.5112372326 144266.08823319848 119232.41993535402 105355.89709609657 0.9784668674725463 0.3918536386122619 0.7010532227266281 1.1471746468527642 0.8490780664997466 1.147412160738042 0.7871178882525509 1.3693214353403624 1.1317109266945018 1.0 16.68491154296496 -5.710778021174458 6.755987577455105 1.0601861793929377 0.6557585303894508 0.40904520358861973 0.20342118060729575 0.18565312849051102 18.80903816683653 0.05388144882533057 0.09302749537564484 1.9463546582112248e-06 5.710778021174458 -0.40442764900348693 LQEEERER ddPTM_PC-9_Lapatinib_30min_R1 1 LQEEERER 8 1 H3BNC9;P08708;H0YN88;A0A075B716 H3BNC9 RPS17 40S ribosomal protein S17 0 93.429 0.0093741 8039200.0 39175.0 19956.0 37986.0 33757.0 30101.0 30505.0 22137.0 17732.0 28481.0 19296.0 False True 38616.35731618486 19909.79310809298 34862.937710200364 36239.602390050866 28330.518360842976 29200.372260628188 23283.145542827107 18555.89345384856 25273.169861774026 22631.28788969617 1.706326105009983 0.8797463584543829 1.540475198765562 1.6013053506579467 1.251829701381759 1.2902656005680908 1.028803383011522 0.8199221159789539 1.1167358209994174 1.0 14.466031066638077 -7.1611232421024935 2.0904463151874926 0.9648148060991669 1.3875078050353358 0.4296575743504881 0.2217144175770946 0.32542991832299456 2.7880032580703658 0.10357412889997615 0.07191145546911283 6.900439585338203e-08 7.1611232421024935 0.42269299893616885 LQEKEDLQELNDR ddPTM_PC-9_AZD4547_30min_R2 2 LQEKEDLQELNDR 13 1 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ; 107.46 0.0013026 76627000.0 171990.0 164442.0 245960.0 331250.0 293500.0 213410.0 182946.0 266640.0 248220.0 256292.0 False True 226679.24238576388 217594.66066142367 242698.40969259077 254885.43026148315 252752.59117877344 200065.43896351216 199227.83958663756 225436.91477764802 261340.40244882682 247319.2950892137 0.9165449153653601 0.8798127157160638 0.9813161144788316 1.030592579400407 1.0219687513163898 0.808935828849682 0.8055491162336184 0.9115217423546667 1.0566923310797702 1.0 17.916015273176463 -6.735645791291022 24.99982532534906 0.9040728618104145 0.9656903350784165 0.07222201098701386 0.08289884674281464 563.1464430355301 545814.8167532531 0.029534750507002015 0.029524998627903115 1.8380368271067815e-07 6.735645791291022 0.06161747326800204 LQEKEDLQELNDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LQEKEDLQELNDR 13 1 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ; 100.38 0.0029425999999999996 32215900.0 88874.0 70917.0 81438.0 99037.0 96972.0 99213.0 107556.0 94762.0 78545.0 81166.0 False True 103918.61285848697 77957.17108587478 83379.79077533507 93488.27797228635 77971.03271932677 94010.09562549536 97367.51704199356 92274.59790863829 79693.5720324591 95880.75329029764 1.0838318358206172 0.8130638153190587 0.8696196881441527 0.9750473871354807 0.8132083869142569 0.9804897479357667 1.0155063837180591 0.9623891630185569 0.8311738205807718 1.0 16.54895362316215 LQEKEDLQELNDR ddPTM_PC-9_Lapatinib_30min_R1 3 LQEKEDLQELNDR 13 1 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ;; 164.92 0.00041609 74960400.0 314732.0 273004.0 305297.0 291691.0 279019.0 291542.0 265794.0 265859.0 306840.0 232013.0 False True 310243.86396521976 272371.87601131597 280196.6591405005 313142.9291926509 262607.6509924603 279073.42827759543 279555.51277997 278211.7797059964 272280.44803155586 272116.13791210996 1.1401156371895318 1.0009398123211957 1.0296951194824042 1.1507694163063276 0.965057247274615 1.0255673567134507 1.0273389697683526 1.0224008830959348 1.0006038235023715 1.0 18.053862992933198 -6.283903831286026 24.999597036335462 1.0099106066958452 1.0710853696063372 0.37859706944949956 0.0454420868906101 1016.3667976747114 1131061.2692476076 0.014035934248953032 0.015929738025416366 5.201111554532821e-07 6.283903831286026 0.06117476291049195 LQELAS(ph)PPAGRPTPAPR ddPTM_PC-9_AZD4547_30min_R2 1 LQELASPPAGRPTPAPR 17 1 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 LQELAS(1)PPAGRPTPAPR 89.506 0.0012004000000000001 26827000.0 18518.0 15300.0 33560.0 46071.0 46179.0 49359.0 28406.0 57134.0 37409.0 26991.0 True False 24406.33880167203 20245.425792192866 33114.97247228554 35450.04273985451 39767.84295756251 46272.573927182304 30934.07897028639 48305.25310870892 39386.36336801288 26046.053305421006 0.9370455675368022 0.777293417731705 1.2714007793800095 1.361052376118582 1.526827980087316 1.7765675814520245 1.187668573336139 1.8546093161321708 1.5121816309811256 1.0 14.668777160572818 -5.506085499631705 1.8879072375045887 1.510899684654536 0.8388095619236847 0.47928951107442497 0.243546406155965 0.2718742616970516 1.875505842992728 0.06819570357087518 0.18890967557915603 3.118275628184952e-06 5.506085499631705 -0.6720901227308512 LQELAS(ph)PPAGRPTPAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LQELASPPAGRPTPAPR 17 1 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 LQELAS(0.991)PPAGRPT(0.009)PAPR;LQELAS(0.983)PPAGRPT(0.017)PAPR 83.964 0.016822999999999998 22986100.0 29709.0 32275.0 43242.0 44764.0 55008.0 51461.0 52628.0 52187.0 47071.0 41630.0 True False 34738.14692050314 35479.04870195587 44273.05327619823 42256.01820684608 44229.57727823205 48762.29456808703 47642.69484627565 50817.14654669714 47759.32432541696 49177.18945710135 0.7063873983853064 0.7214533626999007 0.9002762005099716 0.8592605367109725 0.8993921321350574 0.9915632655384619 0.968796618355665 1.0333479222318382 0.9711682357748151 1.0 15.585701664866379 -4.768572954815798 0.4546575876370923 1.0112586099310896 0.4444679691414619 0.8976844054762033 0.034557828751606734 1.4308331235994851 0.22805319832027168 0.02443202608545511 0.4421170246788541 1.7038330774345927e-05 4.768572954815798 -0.5667906407896277 LQELAS(ph)PPAGRPTPAPR ddPTM_PC-9_Lapatinib_30min_R1 1 LQELASPPAGRPTPAPR 17 1 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 LQELAS(0.94)PPAGRPT(0.06)PAPR 76.051 0.041379 4909300.0 15714.0 11585.0 15793.0 12270.0 18897.0 15473.0 16756.0 18034.0 17418.0 10748.0 True False 15489.915478405337 11558.175644280283 14494.560502742968 13172.376731520098 17785.51561293145 14811.255859324681 17623.543692262338 18871.92547635378 15456.201420328634 12605.777479190217 1.2287949318458375 0.9168951033254927 1.1498347108435618 1.0449475848090473 1.410901917179802 1.1749577432867824 1.3980528945045647 1.4970854044907425 1.226120439286187 1.0 13.621797480751159 -6.25084279301599 24.982147472163994 1.3095725625445898 1.077724759036231 0.2852367292187574 0.1513739179581413 784.7922995604551 1850198.0622977603 0.042801361041288906 0.05466328659286238 5.612511023196904e-07 6.25084279301599 -0.23184780350835865 LQELASPPAGRPT(ph)PAPR ddPTM_PC-9_AZD4547_30min_R2 1 LQELASPPAGRPTPAPR 17 1 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 LQELAS(0.106)PPAGRPT(0.894)PAPR 83.204 0.040805 5272500.0 9300.2 10619.0 14984.0 26762.0 18448.0 20787.0 16608.0 24719.0 15778.0 18094.0 True False 12257.470143822788 14051.384084136987 14785.302369628316 20592.434368778322 15886.81363565934 19487.18560392916 18086.07982604086 20899.246536111183 16611.99286857459 17460.534567384962 0.7020100155878888 0.8047510819275816 0.8467840610817386 1.1793702128251862 0.9098698309807066 1.1160703888373404 1.0358262375210647 1.1969419639161272 0.9514023069834651 1.0 14.091810108385616 -5.6004731226213424 5.196585958307419 1.0589084389186112 0.7691356261326543 0.6626202920172772 0.08998256937370439 0.11061328913454081 5.252038404063636 0.023416834963127874 0.04165739815485838 2.5091514596495072e-06 5.6004731226213424 -0.2897728127859569 LQELASPPAGRPT(ph)PAPR ddPTM_PC-9_Lapatinib_30min_R1 1 LQELASPPAGRPTPAPR 17 1 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 LQELAS(0.258)PPAGRPT(0.742)PAPR 54.236999999999995 0.040543 28144000.0 38058.0 41321.0 40017.0 29531.0 36903.0 41843.0 32393.0 38036.0 41069.0 25620.0 True False 37515.28594101755 41225.32376325468 36726.95673008707 31702.80825252814 34732.43809408949 40053.472430797054 34070.15103983372 39803.29141724476 36443.37674425748 30048.382863495845 1.2484960043088655 1.3719648059109728 1.2222606752892737 1.0550587163558198 1.1558837709128118 1.332965990640909 1.1338430821587975 1.3246400512820817 1.2128232294500803 1.0 14.874999729967001 -11.72695161662782 2.0390797063755515 0.4040932002929829 1.2285419599960197 0.35435730264411247 0.09259457539215785 2005023.5345805208 403730.4749890773 5497527.582078326 0.026662848782484382 1.87520340690086e-12 11.72695161662782 0.8244487597030368 LQELESCSGLGS(ph)TSDDTDVR ddPTM_PC-9_AZD4547_30min_R2 2 LQELESCSGLGSTSDDTDVR 20 0 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7;B4DGD8 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 LQELESCS(0.001)GLGS(0.993)T(0.005)SDDTDVR;LQELESCS(0.001)GLGS(0.7)T(0.279)S(0.019)DDTDVR 153.36 2.5756999999999998e-05 8090000.0 21288.0 24796.0 30526.0 29543.0 25761.0 31459.0 30670.0 36470.0 30188.0 29657.0 True False 28057.141182092786 32810.82208779179 30121.20529466594 22732.317784800027 22184.52981722791 29491.863756867628 33399.57058433723 30834.39949722783 31783.67604997655 28618.717456888266 0.9803773081151715 1.1464812194053975 1.0525001806961143 0.7943164405967663 0.7751755420433174 1.0305096236857814 1.1670533675959072 1.0774207315082274 1.1105905111875134 1.0 14.804671398921952 -6.996836106622003 24.975449093991738 1.0957269849531033 0.9522767551677986 0.2644761456233139 0.10939524785689247 145.05100301996646 1145003.5497877188 0.04367548489528375 0.03832301173838481 1.0073117348731135e-07 6.996836106622003 -0.14345022978530464 LQELESCSGLGS(ph)TSDDTDVR ddPTM_PC-9_Lapatinib_30min_R1 2 LQELESCSGLGSTSDDTDVR 20 0 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7;B4DGD8 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 LQELESCS(0.011)GLGS(0.247)T(0.247)S(0.247)DDT(0.247)DVR;LQELESCS(0.008)GLGS(0.673)T(0.067)S(0.248)DDT(0.004)DVR 149.44 1.2631e-14 3492900.0 11939.1 16589.6 16344.2 13417.699999999999 18187.5 21269.9 19829.8 20304.4 19017.9 16661.5 True False 11768.846244637205 16551.187800461976 15000.442966436494 14404.482418135067 17117.747008000784 20360.23595955859 20856.49001604343 21247.816548856463 16875.903834634744 19541.418074946774 0.6022513923759476 0.8469798730564776 0.7676230511473437 0.7371257481360804 0.875972610705603 1.0419016614593384 1.0672966483830901 1.0873221414825258 0.8635966832044102 1.0 14.254247543655147 -6.530189370536961 2.9115610932442393 1.02089094834501 0.7488571064269001 0.7180846093552784 0.08042289441548352 0.1423536069183897 2.461239538082663 0.027447080177151334 0.029128312301854496 2.9499226566749556e-07 6.530189370536961 -0.27203384191810986 LQELESCSGLGSTSDDT(ph)DVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQELESCSGLGSTSDDTDVR 20 0 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7;B4DGD8 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 LQELESCSGLGS(0.032)T(0.006)S(0.006)DDT(0.956)DVR 126.22 3.0286e-06 0.0 1224.7 3136.8 3075.8 2230.5 2671.7 2421.8 3526.7 2095.3 2568.2 2340.9 True False 1432.017521072409 3448.200773611003 3149.1387370364573 2105.532316378569 2148.1995639589236 2294.796544664758 3192.6254449031 2040.300595153861 2605.7550664429427 2765.286639445795 0.5178550030384578 1.246959618733078 1.1388109616251543 0.7614155749150653 0.7768451679893318 0.8298584717874563 1.1545368929793658 0.7378260777923433 0.9423092092055871 1.0 11.433213317336739 -4.729800348015177 24.710715745396236 0.9426555687679256 0.5178517174906315 0.3664406755308087 0.17154575964776925 4675.062905386963 3651078.924494592 0.044692476739320836 6.567740499714464 1.862943364120158e-05 4.729800348015177 -0.42480385127729403 LQELNAHIVVS(ph)DPEDITDCPR ddPTM_PC-9_AZD4547_30min_R2 3 LQELNAHIVVSDPEDITDCPR 21 0 Q16513-3;Q16513-2;Q16513;B1AL79 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 LQELNAHIVVS(0.998)DPEDIT(0.002)DCPR;LQELNAHIVVS(0.998)DPEDIT(0.002)DCPR;LQELNAHIVVS(1)DPEDITDCPR 114.62 2.0719e-06 5955200.0 33046.0 34384.4 45949.2 64448.9 52793.9 50917.0 48347.1 60167.7 44688.9 44764.0 True False 43553.94060049974 45498.4848764102 45339.883585326075 49591.20183057908 45464.378274047915 47733.15194088903 52649.89823925695 50870.164481199754 47051.06401980243 43196.82598510115 1.008267149431807 1.0532830558454203 1.049611459901338 1.1480288354446084 1.05249349314991 1.1050152610136792 1.21883719552488 1.1776366277176287 1.0892250286173948 1.0 15.39863768953581 -5.292543495550133 0.8241685177342927 1.1281005239006374 0.9894285445605269 0.22321446315969096 0.06044728740266631 1.7958499216012456 1.5386536909966917 0.024915899158456222 0.19857253595512378 5.098665307601974e-06 5.292543495550133 -0.13867197934011055 LQELNAHIVVS(ph)DPEDITDCPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQELNAHIVVSDPEDITDCPR 21 0 Q16513-3;Q16513-2;Q16513;B1AL79 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 LQELNAHIVVS(0.987)DPEDIT(0.013)DCPR 80.944 0.00046092 3113000.0 6768.7 7841.0 9135.6 10989.0 9458.2 9522.2 11107.0 8788.3 8565.9 8439.1 True False 7914.50722208118 8619.402660636279 9353.427350955932 10373.32195681869 7604.933606256802 9022.839069124933 10054.864552283652 8557.616436973542 8691.16008240932 9969.042026121158 0.793908502075061 0.8646169449433038 0.9382473588182118 1.0405535386086473 0.7628550051579827 0.9050858693827393 1.0086089040388855 0.8584191354144801 0.8718149707500985 1.0 13.283239160342045 -14.522878745258238 0.012211586217386853 2.0253571330997864 2.392717108320771e-08 0.1322652140126116 0.08157333620578316 22496.614594665 20.779442577786988 2070.759972824117 1430.4995830845517 3.0000000001526602e-15 14.522878745258238 -2.0253571091726155 LQETS(ph)SQSYVEEQK ddPTM_PC-9_Lapatinib_30min_R1 1 LQETSSQSYVEEQK 14 0 A0A494C108;Q8N9T8;H0YFD2;F8WFC1 A0A494C108 KRI1 Protein KRI1 homolog 1 LQET(0.009)S(0.874)S(0.116)QS(0.001)YVEEQK 173.19 2.4601999999999994e-19 0.0 10758.0 19252.0 12325.0 11185.0 12872.0 12711.0 13261.0 11849.0 11941.0 11417.0 True False 10604.588947224423 19207.423176839362 11311.686075875828 12007.582212066209 12114.894267325688 12167.380160788218 13947.589693428663 12399.547796901172 10596.07883569551 13390.413237803761 0.7919538224022534 1.4344160135859767 0.8447600439948127 0.8967297721751 0.9047438680326135 0.9086635299975149 1.041610101624936 0.92600187736513 0.7913182847696368 1.0 13.708912863507482 LQEYQSAIKVEPAS(ph)PPYYSEK ddPTM_PC-9_AZD4547_30min_R2 2 LQEYQSAIKVEPASPPYYSEK 21 1 E7EU07;E7EUD1;A0A499FIV4;E9PFX5;A0A494C0D9;E9PFV2;P37231-3;P37231-2;P37231 E7EU07 PPARG Peroxisome proliferator-activated receptor gamma 1 LQEYQSAIKVEPAS(0.992)PPY(0.004)Y(0.001)S(0.003)EK;LQEYQSAIKVEPAS(1)PPYYSEK 119.2 7.0139e-05 0.0 46465.0 25194.0 55778.0 108023.0 75586.0 44492.0 32534.0 44673.0 32470.0 51792.0 True False 61239.90346796043 33337.46780447758 55038.34727530221 83119.96628871319 65092.188609331526 41709.90820657217 35429.46297329075 37769.81433341537 34186.2979111812 49978.77784425787 1.2253181472102836 0.6670324734302755 1.1012343568466358 1.6631052193338687 1.3023965654416267 0.8345523841448691 0.7088901430061937 0.7557170455650667 0.6840162842259039 1.0 15.609028002470938 -6.8507207871187354 5.843293702451346 0.7689677153655182 1.1828284156752706 0.39923814996840346 0.24193938814758792 0.23977518050355393 12.52617979187342 0.0948559286209808 0.08390364667308589 1.410195137598566e-07 6.8507207871187354 0.4138607003097524 LQEYQSAIKVEPAS(ph)PPYYSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LQEYQSAIKVEPASPPYYSEK 21 1 E7EU07;E7EUD1;A0A499FIV4;E9PFX5;A0A494C0D9;E9PFV2;P37231-3;P37231-2;P37231 E7EU07 PPARG Peroxisome proliferator-activated receptor gamma 1 LQEYQS(0.002)AIKVEPAS(0.884)PPY(0.021)Y(0.029)S(0.065)EK;LQEY(0.037)QS(0.119)AIKVEPAS(0.78)PPY(0.023)Y(0.019)S(0.022)EK 76.161 0.00064265 10813600.0 52294.0 17192.1 37700.0 81404.0 83533.0 94658.0 67756.0 118343.0 93848.0 63510.0 True False 61146.34134641998 18898.818069369332 38598.91097804618 76843.19779532874 67165.30829665788 89693.96784411457 61337.66116904026 115236.62164477329 95220.34945702704 75023.86025511673 0.8150252618099548 0.2519041009767344 0.5144884686923809 1.024250119015809 0.8952526312064449 1.1955392263089704 0.8175753814914762 1.5359996306896777 1.2692008800031438 1.0 16.195061876454908 -6.019729328847466 1.245492751717178 1.1755780615958575 0.4783000499567381 0.554190727548483 0.23379428966755417 0.3341110563672913 1.0539629219451214 0.08819868739946894 0.1640075513243253 9.555879643239255e-07 6.019729328847466 -0.6972780116391195 LQFHDVAGDIFHQQCK ddPTM_PC-9_AZD4547_30min_R2 2 LQFHDVAGDIFHQQCK 16 0 P11413;P11413-2;P11413-3 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ; 152.0 1.3152e-05 23567000.0 78818.0 65798.0 111985.0 120084.0 112745.0 98099.0 86624.0 111975.0 86897.0 86685.0 False True 103880.48448375541 87065.91674998072 110500.0057303007 92400.48907930548 97092.30287036086 91964.85402221781 94333.36818707615 94671.83667951993 91490.1980162584 83650.18453486051 1.2418440564284003 1.0408335287496793 1.3209774293355057 1.104605920394573 1.160694425364937 1.0993981009556797 1.1277126130877035 1.1317588503354254 1.0937238037787067 1.0 16.352081102445887 -14.522878721483567 0.09240910210315115 0.49901558359569564 1.265894035820987 0.3533433664472293 0.07085350860138981 231.43046161096524 1.473234697041298 22.36752196064886 1.4550150118877585 3.0000001643822748e-15 14.522878721483567 0.7668784522252913 LQFHDVAGDIFHQQCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LQFHDVAGDIFHQQCK 16 0 P11413;P11413-2;P11413-3 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ; 155.09 1.5742999999999998e-05 23862000.0 69628.0 71064.0 74175.0 83412.0 90323.0 78680.0 81921.0 70498.0 71617.0 61200.0 False True 81414.64518431434 78118.76427438544 75943.61331025416 78738.69606535263 72624.8565390806 74553.88229177601 74160.84982332132 68647.5021988055 72664.26313894716 72295.07554106656 1.126143718296103 1.0805544318161862 1.0504673069622161 1.0891294528162687 1.0045615969766393 1.0312442684899936 1.025807764474842 0.9495460331846656 1.0051066769778931 1.0 16.141609759306174 -5.596044697113599 0.43893065037321943 0.9827328999715219 1.1535359876338396 0.7339192977175143 0.025260896432901973 1.3559799987534034 0.341658632442086 0.02103890087217239 0.11299678089470253 2.534867731254917e-06 5.596044697113599 0.17080308766231767 LQFHDVAGDIFHQQCK ddPTM_PC-9_Lapatinib_30min_R1 1 LQFHDVAGDIFHQQCK 16 0 P11413;P11413-2;P11413-3 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 120.92 3.5236999999999995e-05 6068800.0 133190.0 126070.0 130780.0 124910.0 140750.0 124860.0 131200.0 111420.0 130260.0 109800.0 False True 131290.68617594565 125778.0926607177 120027.77322539887 134096.29808754515 132471.36172514688 119520.02886287613 137992.89403346973 116596.97995870783 115588.74710138999 128778.78370069676 1.0195055614214137 0.9766988710892536 0.93204617854105 1.0412918512975489 1.0286738072711752 0.9281034144619699 1.0715499096045826 0.9054051964778494 0.8975760119775428 1.0 16.97453540351792 -7.797787984392322 24.999993316010848 0.9261178955351121 0.9961702183354642 0.2567040703899506 0.05014523319874991 227.08791233816711 156184.5932959306 0.026469597642388404 0.012716193907185234 1.5929862076022382e-08 7.797787984392322 0.07005232280035201 LQGINCGPDFTPS(ph)FANLGR ddPTM_PC-9_AZD4547_30min_R2 1 LQGINCGPDFTPSFANLGR 19 0 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73;C9JF13;C9K073;C9J6B6;C9J2Z7 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 LQGINCGPDFT(0.152)PS(0.848)FANLGR 79.676 0.024465 0.0 4950.1 5136.5 4383.1 9862.5 6887.9 6677.3 6931.9 5569.0 6162.4 5076.2 True False 6524.128831523751 6796.773175267882 4324.977230133334 7588.852999106055 5931.633978808436 6259.767375432536 7548.825671130335 4708.439012888997 6488.131883211058 4898.483783075031 1.3318669858754169 1.3875259113343836 0.8829216185377106 1.549224889817261 1.210912241723263 1.2778989688729676 1.541053518889379 0.9612033480966772 1.3245183960041862 1.0 12.258119548759284 -10.64655093802297 4.149584350107731 0.9999413375434373 1.2709446507954019 0.13832478901953926 0.20511590878001262 26758211.260520715 22884441.58244819 13111.282848057726 0.04718101276847616 2.2565713086841837e-11 10.64655093802297 0.2710033132519646 LQGIS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 LQGISPK 7 0 Q16385;Q16385-2 Q16385 SSX2 Protein SSX2 1 LQGIS(1)PK 70.1 0.044851999999999996 28932000.0 204810.0 211760.0 204930.0 239290.0 214790.0 211700.0 214950.0 216490.0 191930.0 215340.0 True False 269935.3196873553 280207.2788075008 202212.49430111682 184125.38749364638 184970.11604527707 198462.36553383362 234080.13358667356 183036.44494529304 202075.0279671393 207801.012144395 1.2990086857699468 1.348440394567437 0.9731063973865782 0.8860658838644294 0.8901309677777055 0.9550596673510319 1.126462913587822 0.8808255698875337 0.9724448686839077 1.0 17.664843155686363 -5.269751120282041 11.79480030746234 0.9567841791939359 1.323780583548625 0.8158826140958129 0.06899858896928292 0.1915403590475281 271.84206362439625 0.018661822324201684 0.041350748903759095 5.373396396238492e-06 5.269751120282041 0.36699640435468905 LQGQVS(ph)AK ddPTM_PC-9_AZD4547_30min_R2 2 LQGQVSAK 8 0 O95235-2;O95235 O95235-2 KIF20A Kinesin-like protein KIF20A 1 LQGQVS(1)AK;LQGQVS(1)AK 73.781 0.029015 19134400.0 100851.0 103156.0 113067.0 132235.0 141654.0 123030.0 110995.0 146480.0 108008.0 132451.0 True False 132919.5201688859 136499.15967447378 111567.65770333468 101750.26376038422 121987.78722602363 115336.91465105143 120873.3399741935 123844.88177553946 113717.08237729786 127813.9308049468 1.0399454842816047 1.0679521302163946 0.8728912177311479 0.7960811714308544 0.9544169908379214 0.9023814065077446 0.9456976967452387 0.9689466632908397 0.8897080440381594 1.0 16.963685562739784 -5.254988011855874 24.972104848415533 0.9127819101317411 1.0539488237472772 0.5034316330102254 0.05460906269286111 406.69638497150845 1574239.405867097 0.014418181788571436 0.036208744316134 5.5591960250874845e-06 5.254988011855874 0.14116691361553602 LQGQVS(ph)AK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQGQVSAK 8 0 O95235-2;O95235 O95235-2 KIF20A Kinesin-like protein KIF20A 1 LQGQVS(1)AK 70.399 0.038245 7341000.0 42303.0 42770.0 36247.0 46214.0 44659.0 33453.0 38757.0 30882.0 26517.0 31009.0 True False 49464.06237766485 47015.92294291717 37111.265947513 43624.77940780952 35908.389537313924 31698.66578935923 35085.656383619105 30071.38022218372 26904.760959764633 36630.68623289107 1.3503449556795515 1.2835119343382948 1.0131195935442348 1.1909353575974881 0.9802816498990786 0.8653582296499996 0.9578214331162416 0.820934121490258 0.7344869486940315 1.0 15.160765108046517 -5.394724751240472 0.530564780165848 0.8411004660808218 1.5091689489697941 0.7553750659528367 0.09367782309034099 1.1372024757349433 0.3868089911592852 0.06149703462492061 0.43701254331268774 4.029723507128581e-06 5.394724751240472 0.6680684828889724 LQGQVS(ph)AK ddPTM_PC-9_Lapatinib_30min_R1 1 LQGQVSAK 8 0 O95235-2;O95235 O95235-2 KIF20A Kinesin-like protein KIF20A 1 LQGQVS(1)AK 70.41199999999999 0.03821 8344700.0 74711.0 66291.0 65010.0 67578.0 46732.0 49117.0 46464.0 41890.0 56162.0 35925.0 True False 73645.60743968052 66137.50726240696 59665.12874585702 72547.91155359942 43983.315638646985 47016.38040731925 48869.678569901946 43836.36232696348 49836.44414792151 42134.58838294648 1.747865833417938 1.5696725612056863 1.4160605582183838 1.7218137007590277 1.0438767133286808 1.1158618657907342 1.1598470626019315 1.040389001277292 1.1827917646892754 1.0 15.362717410970054 -6.266479234138072 24.989413400900716 1.0972198417499086 1.5965693692252139 0.8688683166804912 0.09950018056344509 144.28062654130844 715394.2159166887 0.030062417029554124 0.03514262638533697 5.414031345435269e-07 6.266479234138072 0.49934952747530525 LQHSTS(ph)ILR ddPTM_PC-9_AZD4547_30min_R2 1 LQHSTSILR 9 0 A0A2R8Y7T6;A0A3B3IRZ4;Q6DN90;Q6DN90-3;A0A2R8Y695 A0A2R8Y7T6 IQSEC1 IQ motif and SEC7 domain-containing protein 1 1 LQHS(0.01)T(0.064)S(0.926)ILR 74.392 0.015581999999999999 2613000.0 9784.6 10719.0 21860.0 22862.0 20637.0 17488.0 17726.0 26537.0 19105.0 18203.0 True False 12895.89926767687 14183.707128530423 21570.12211692974 17591.51911437897 17771.90877054975 16394.4725954449 19303.57966018787 22436.316409595132 20114.85129636948 17565.71851056199 0.7341515384026431 0.807465240889633 1.2279669689548973 1.00146880435329 1.0117382195247966 0.9333220605571677 1.0989348171884303 1.2772786035541062 1.1451197560905202 1.0 14.100474969512744 -5.136250503869932 5.645529350408601 1.0854583004521767 0.7530864206820904 0.6065825342384783 0.1023736721380996 0.15438891806272678 6.341732921112957 0.028405673404937434 0.07901677440204069 7.307174793284304e-06 5.136250503869932 -0.3323718797700863 LQINS(ph)PPFDQPMSR ddPTM_PC-9_AZD4547_30min_R2 1 LQINSPPFDQPMSR 14 0 Q00537-2;Q00537;F5H6Z0;F8VQZ9 Q00537-2 CDK17 Cyclin-dependent kinase 17 1 LQINS(0.996)PPFDQPMS(0.004)R 101.04 0.0015928 8893400.0 8603.9 12108.0 18804.0 28957.0 25291.0 22714.0 20204.0 26671.0 17667.0 21238.0 True False 11339.761227762501 16021.674215154986 18554.64667368466 22281.411031190255 21779.78120443738 21293.689989303257 22002.116859665777 22549.609788608817 18600.84155210466 20494.46408434408 0.5533085022908726 0.7817561927561746 0.9053492005120902 1.0871916893992482 1.0627153320430158 1.0389971604853876 1.0735639033602937 1.1002780895273414 0.9076032179008781 1.0 14.322946644566402 -4.978126394622042 1.3220841320833536 1.0456609403739208 0.44844142962040817 0.8782626695545056 0.05725167263733906 0.28863007969319027 0.5772077112265391 0.01693541660048028 0.2119372104182871 1.0516557613061222e-05 4.978126394622042 -0.5972195107535125 LQINS(ph)PPFDQPMSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LQINSPPFDQPMSR 14 0 Q00537-2;Q00537;F5H6Z0;F8VQZ9 Q00537-2 CDK17 Cyclin-dependent kinase 17 1 LQINS(0.848)PPFDQPMS(0.152)R;LQINS(0.998)PPFDQPMS(0.002)R 109.1 0.00054768 11864000.0 18826.9 27337.0 42548.0 40259.0 51614.0 43810.0 46860.0 50563.0 44029.0 34851.0 True False 22013.92232177524 30050.83669606093 43562.50568418855 38003.41875143904 41500.607214199146 41512.52647690275 42421.08156297934 49235.77482592689 44672.84083031552 41169.210419635805 0.5347181084453254 0.7299347349573669 1.0581331349364733 0.923102929691194 1.0080496271651904 1.0083391460212023 1.0304079463896265 1.1959368257022416 1.0851031723700157 1.0 15.329278159163227 -4.530705928459924 0.8859032007785965 1.0611601798080317 9.287802908346714e-14 0.8453957372203977 0.07112820716803614 1.2373281120007924 0.5627441491828664 0.026109381738074016 1.4143781959585393 2.9464160497030835e-05 4.530705928459924 -1.0611601798079389 LQINSPPFDQPMS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 LQINSPPFDQPMSR 14 0 Q00537-2;Q00537;F5H6Z0;F8VQZ9 Q00537-2 CDK17 Cyclin-dependent kinase 17 1 LQINS(0.001)PPFDQPMS(0.999)R 86.344 0.026853 0.0 16465.0 12537.0 13960.0 10540.0 12685.0 13969.0 14164.0 12441.0 15014.0 12721.0 True False 16230.206080688793 12507.971346770986 12812.26268715835 11315.146760409285 11938.893239669549 13371.578433329452 14897.342615015737 13019.054278103431 13322.965215570914 14919.807900332979 1.0878294271018443 0.83834667512655 0.858741799676416 0.7583976171808992 0.8002042197475678 0.8962299328955186 0.9984942644391058 0.8726020043336398 0.8929716323809754 1.0 13.864941339873088 -6.99975853877183 24.998310116215755 0.9328235674919602 0.8591239689661407 0.11950953861208491 0.08966353232448523 18.922831668355933 1958806.484523839 0.03263010922105195 0.028498118731017916 1.0005561396128429e-07 6.99975853877183 -0.07369959852581942 LQIS(ph)TPDIK ddPTM_PC-9_AZD4547_30min_R2 2 LQISTPDIK 9 0 O14896-2;O14896 O14896-2 IRF6 Interferon regulatory factor 6 1 LQIS(0.745)T(0.255)PDIK;LQIS(0.949)T(0.051)PDIK 117.86 0.00048343 0.0 37357.0 53035.0 49242.0 47552.0 42455.0 50460.0 34560.0 47146.0 35077.0 32011.0 True False 49235.74892612927 70177.52659404892 48589.01890584879 36589.62107107639 36560.85607664341 47304.728223132974 37635.77304840873 39860.66900730197 36931.09860888523 30890.304633390093 1.593890041243204 2.2718301883689516 1.5729536980133152 1.1845017880311146 1.183570589884176 1.531377847662924 1.2183684652862663 1.290394169962817 1.1955563095666428 1.0 14.914866478126333 -5.524978852728176 4.6517351960766025 1.255816329883612 1.9375761340174467 0.670168571871103 0.19767897695085349 0.09904594596757785 5.667983312099547 0.05055543445908181 0.09819177892271276 2.9855279908659562e-06 5.524978852728176 0.6817598041338346 LQIS(ph)TPDIK ddPTM_PC-9_Lapatinib_30min_R1 2 LQISTPDIK 9 0 O14896-2;O14896 O14896-2 IRF6 Interferon regulatory factor 6 1 LQIS(0.866)T(0.134)PDIK;LQIS(0.933)T(0.067)PDIK 112.94 0.0021347 4105400.0 34315.0 52250.0 42413.0 32004.0 49286.0 52294.0 60730.0 60795.0 46604.0 38542.0 True False 33825.66180739971 52129.01833523045 38925.966858914566 34357.680922214306 46387.094380004186 50057.50752326796 63874.30224582784 63619.75764305907 41354.96675812354 45203.93334601319 0.7482902328096411 1.153196513591179 0.8611190216779595 0.7600595430318791 1.02617385139772 1.1073706161829573 1.4130253169984666 1.4073942892553637 0.9148532814959318 1.0 15.46416069139116 -6.7282344886618715 2.707206405878826 1.218503042268647 0.9001071085457893 0.344519953970273 0.18182783698881877 0.28705019288819417 4.306983410694853 0.06721840081513301 0.06359203275692935 1.8696723754015116e-07 6.7282344886618715 -0.31839593372285757 LQIS(ph)TPDIKDNIVAQLK ddPTM_PC-9_AZD4547_30min_R2 2 LQISTPDIKDNIVAQLK 17 1 O14896-2;O14896 O14896-2 IRF6 Interferon regulatory factor 6 1 LQIS(0.5)T(0.5)PDIKDNIVAQLK;LQIS(0.79)T(0.21)PDIKDNIVAQLK 57.288000000000004 0.021725 84262000.0 113017.0 117762.0 138553.0 157572.0 120184.0 159910.0 89791.0 112840.0 97494.0 93102.0 True False 148954.05510036522 155826.26353857623 136715.69669107805 121246.20986313213 103498.52612684772 149910.80242095116 97782.22505178451 95403.17080524251 102647.33380205421 89842.52731804312 1.657945958856065 1.7344376676643374 1.5217258549183907 1.349541397404369 1.1519992726881143 1.6685951174354876 1.0883734904922566 1.061893221987341 1.1425250030943808 1.0 16.455110891637062 -4.836615599753984 0.24856993485093204 0.9555884437037949 2.3666054021188216 0.6700062597371469 0.15502808598361115 6.042590250355606 0.32840164513677206 0.23887581776528755 2.6345770629869443 1.4567478984840626e-05 4.836615599753984 1.4110169584150267 LQIS(ph)TPDIKDNIVAQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LQISTPDIKDNIVAQLK 17 1 O14896-2;O14896 O14896-2 IRF6 Interferon regulatory factor 6 1 LQIS(0.5)T(0.5)PDIKDNIVAQLK;LQIS(0.787)T(0.213)PDIKDNIVAQLK 110.61 0.00017955 104986200.0 236450.0 227016.0 162820.0 195540.0 197846.0 172118.6 192302.0 104911.5 165028.0 142268.0 True False 276476.31489962473 249552.64818352295 166702.24629828823 184584.5277492332 159079.49654939445 163092.39761852167 174085.76241408556 102157.68428792252 167441.22229769762 168060.06220713127 1.6451042042271304 1.4849015578487257 0.9919206509208026 1.0983247615470701 0.9465633563394233 0.9704411356072984 1.0358544447016074 0.6078641346807003 0.9963177455648509 1.0 17.35861739769411 -4.8133290779943625 0.8648170041598237 0.9067502745207354 2.1127375207095445 0.7842051933415252 0.12801372001233757 0.9648932217795891 0.5770853938809011 0.04612995355538109 1.102925667569523 1.536989575715834e-05 4.8133290779943625 1.205987246188809 LQIS(ph)TPDIKDNIVAQLK ddPTM_PC-9_Lapatinib_30min_R1 2 LQISTPDIKDNIVAQLK 17 1 O14896-2;O14896 O14896-2 IRF6 Interferon regulatory factor 6 1 LQIS(0.861)T(0.139)PDIKDNIVAQLK;LQIS(0.962)T(0.038)PDIKDNIVAQLK 109.5 0.00021435 100436000.0 219530.0 183934.0 190662.0 138831.0 195764.0 206623.0 218299.0 219000.0 213604.0 165377.0 True False 216399.46194312867 183508.11212387145 174986.50633660352 149041.09486663985 184249.54640683235 197786.21595173824 229601.45407478983 229175.5394988065 189545.6681701618 193962.19409899926 1.1156785627650578 0.9461024761877462 0.9021681114170607 0.7684028094184608 0.9499250473150993 1.0197152948826058 1.1837433327733966 1.181547468894037 0.9772299651003987 1.0 17.56541595313233 -6.913407762343408 3.375878144630584 1.101044050042318 0.9255778613257107 0.3192272744020862 0.10086105517702672 0.2658552738668749 6.031207363882448 0.03964897967466935 0.034134700964503696 1.220653041677068e-07 6.913407762343408 -0.17546618871660724 LQIST(ph)PDIKDNIVAQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQISTPDIKDNIVAQLK 17 1 O14896-2;O14896 O14896-2 IRF6 Interferon regulatory factor 6 1 LQIS(0.267)T(0.733)PDIKDNIVAQLK 80.719 0.004010199999999999 76703000.0 228400.0 232150.0 167270.0 167630.0 189830.0 151450.0 191360.0 120010.0 144930.0 128190.0 True False 267063.6088943733 255196.3177740995 171258.35117500758 158238.23456379227 152634.1742060573 143507.6953875125 173232.99547357543 116859.86466110568 147049.32706937756 151429.8322485185 1.7636129217661871 1.6852446706490767 1.130941959269608 1.0449607730140003 1.0079531353872353 0.9476844374495204 1.1439819545548644 0.771709661999239 0.9710723764657422 1.0 17.20828992412843 -5.296123518581758 2.2676253133335793 0.9791999785557436 1.7865743466107133 0.9167537604911168 0.08813270829658103 0.08235048552015689 0.7941410928675576 0.024878686282977958 0.08355657016241957 5.05680819832743e-06 5.296123518581758 0.8073743680549698 LQIT(ph)PDSNGEQFSSLIQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQITPDSNGEQFSSLIQR 18 0 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5;Q96PU5-3;K7ERN1 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 LQIT(0.966)PDS(0.033)NGEQFSSLIQR 81.51 0.007559000000000001 3379900.0 17068.0 24381.0 25616.0 25667.0 31597.0 24822.0 26868.0 24790.0 23571.0 20260.0 True False 19957.275291633767 26801.384551584357 26226.78258922098 24228.961203536735 25405.794670962354 23520.29062336636 24322.86853252518 24139.28876717616 23915.681283049074 23932.97762192825 0.8338818348013746 1.119851653019053 1.0958428576472266 1.0123671858255237 1.0615392314445928 0.9827565543627228 1.016290948696651 1.008620370958726 0.999277301004814 1.0 14.546712280527299 -6.771040818348406 24.981778874787718 1.0028591825978832 1.0332505567741455 0.01816735061288477 0.07282892633241894 808.0791222918359 2102509.0021019136 0.025072574552868605 0.02237285412870006 1.6941785609829992e-07 6.771040818348406 0.030391374176262254 LQIT(ph)PDSNGEQFSSLIQR ddPTM_PC-9_Lapatinib_30min_R1 2 LQITPDSNGEQFSSLIQR 18 0 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5;Q96PU5-3;K7ERN1 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 LQIT(0.99)PDS(0.01)NGEQFSSLIQR;LQIT(0.84)PDS(0.106)NGEQFS(0.027)S(0.027)LIQR 121.51 0.00016484 7811800.0 21682.0 22201.7 25282.0 21008.0 23055.6 26348.0 19183.3 17518.4 27049.0 21774.7 True False 21372.81070400817 22150.29332771839 23203.411551342222 22552.998400633594 21699.514937053606 25221.157460187856 20176.51740939223 18332.368818063438 24002.456781402547 25538.42788203605 0.8368882690324877 0.8673319058648515 0.9085685171585562 0.8831004987780617 0.8496809215228645 0.9875767442180197 0.7900453975706377 0.7178346647938569 0.9398564740269734 1.0 14.640382096579149 LQLATLEAGPGAAGAGS(ph)E ddPTM_PC-9_AZD4547_30min_R2 1 LQLATLEAGPGAAGAGSE 18 0 C9JI98 C9JI98 TMEM238 Transmembrane protein 238 1 LQLATLEAGPGAAGAGS(1)E 130.29 1.3542999999999999e-05 0.0 6970.4 7557.3 9330.3 11769.0 8799.9 7871.1 9553.1 7549.3 8865.2 8475.6 True False 9186.84220667322 10000.04943394374 9206.574125690277 9055.838879237434 7578.185782330807 7378.918872713078 10403.30739319309 6382.7291506559395 9333.796373335497 8178.871823771865 1.1232407604153536 1.222668559846925 1.1256533081899387 1.1072234746260072 0.9265563693399418 0.9021927512381688 1.2719733989418822 0.7803923680653067 1.141208295526389 1.0 12.997686139259521 -6.022303751484963 3.6614513960927746 1.0011858621061045 1.160922552498201 0.22973592433358914 0.12809406395441283 0.32821358057330413 9.425546506014582 0.03672839334280792 0.05225385696213061 9.499401601501239e-07 6.022303751484963 0.15973669039209648 LQLDNQY(ph)AVLENQK ddPTM_PC-9_Lapatinib_30min_R1 1 LQLDNQYAVLENQK 14 0 D6R9V8;Q9UKY7 D6R9V8 CDV3 Protein CDV3 homolog 1 LQLDNQY(1)AVLENQK 164.81 6.5766e-14 0.0 14412.0 11065.0 12235.0 8581.7 12601.0 12418.0 13167.0 9038.9 14365.0 10454.0 True False 14206.482237162894 11039.379672331577 11229.085528465792 9212.826845711988 11859.833954519192 11886.911087771856 13848.722833374202 9458.880292126762 12747.062429843894 12260.959970920605 1.1586761779547847 0.9003682989352989 0.9158406482932726 0.7513952306803143 0.9672842895374615 0.9694926919233173 1.1294974346396451 0.7714632716003027 1.0396463621181524 1.0 13.581784318697887 -6.493243495116179 24.894743507730762 0.976002128876492 0.919608116639112 0.030808631410743637 0.12485963694955848 2554.9560317450687 2146262.442160504 0.03888360927532572 0.044022453320886876 3.2118592463021074e-07 6.493243495116179 -0.05639401223737994 LQLELS(ph)KVR ddPTM_PC-9_Lapatinib_30min_R1 2 LQLELSKVR 9 1 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 LQLELS(1)KVR;LQLELS(1)KVR 59.11600000000001 0.035646 7341500.0 65392.0 64814.0 62177.0 60489.0 59067.0 54919.0 60502.0 60638.0 57083.0 50212.0 True False 64459.49808857588 64663.927165160305 57065.047070160785 64937.56284538869 55592.795190190096 52570.24239244182 63634.497521440375 63455.46284990241 50653.7114293616 58891.07729671564 1.0945545751150794 1.0980258832651142 0.9689930918167006 1.102672354221142 0.9439935172198066 0.8926690562574182 1.0805456521167984 1.077505553688374 0.8601254002223282 1.0 15.845761444591306 -5.129835262568895 0.947546937411976 0.9875277210718562 1.1346502707798602 0.2190371645278013 0.07671127577186063 2.197142702868174 2.258382637709176 0.027972140048393285 0.2962665617289473 7.415914898880247e-06 5.129835262568895 0.1471225497080041 LQLERPVS(ph)PETQADLQR ddPTM_PC-9_AZD4547_30min_R2 1 LQLERPVSPETQADLQR 17 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 LQLERPVS(0.993)PET(0.007)QADLQR 60.56100000000001 0.016562999999999998 80045000.0 33802.0 34802.0 42277.0 41628.0 38420.0 41809.0 37527.0 50723.0 44539.0 35523.0 True False 44550.33287472286 46051.06590979712 41716.379356698926 32031.307746188766 33086.04617747354 39194.67662070877 40866.83030056809 42884.925848584775 46893.24061182938 34279.3505823597 1.299625929834524 1.343405435851378 1.2169536075799041 0.9344199117550439 0.9651888269581093 1.1433902905056352 1.1921704934981565 1.251042540772448 1.3679734246762785 1.0 15.065052157597181 -5.522339575513866 24.999973388160402 1.1256046954537138 1.3111816760819133 0.28739234163274185 0.12588006381953276 26.582820207324527 1232586.3607122158 0.037910608280889435 0.06665126087697786 3.0037267656824283e-06 5.522339575513866 0.1855769806281995 LQLERPVS(ph)PETQADLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LQLERPVSPETQADLQR 17 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 LQLERPVS(0.809)PET(0.191)QADLQR;LQLERPVS(0.529)PET(0.471)QADLQR;LQLERPVS(0.883)PET(0.117)QADLQR;LQLERPVS(0.942)PET(0.058)QADLQR 64.843 0.010517 133736000.0 85855.0 112373.0 109515.0 93147.0 119698.0 72074.0 95893.0 78513.0 80572.0 77917.0 True False 100388.5557864552 123528.64879271552 112126.25293795027 87928.27557664865 96244.03615928254 68294.31256097442 86809.32083480105 76452.11694139967 81750.21307275181 92042.73530936743 1.090673320920292 1.3420792893379352 1.2181977486987925 0.95529837614137 1.0456451107824425 0.741984821848552 0.9431414716547025 0.8306154384094986 0.8881767018111626 1.0 16.49001623749892 -5.901646333802064 1.8929107149961684 0.8890935258597841 1.2383696473587866 0.6542613437876397 0.09972039989019311 0.18644146908062081 1.3589001815774762 0.03052807631253837 0.053770677229432434 1.2541620817198833e-06 5.901646333802064 0.34927612149900256 LQLGT(ph)PPPLLAAR ddPTM_PC-9_AZD4547_30min_R2 1 LQLGTPPPLLAAR 13 0 Q9P2N5 Q9P2N5 RBM27 RNA-binding protein 27 1 LQLGT(1)PPPLLAAR 132.51 0.00013511 19948000.0 52104.0 46711.0 63440.0 84574.0 76825.0 68035.0 48244.0 69700.0 47157.0 58211.0 True False 68671.98816947402 61809.41726660918 62598.74414904038 65076.77095527463 66159.17484602818 63780.76069482459 52537.62253898811 58929.466546662465 49649.62274707646 56173.050608049445 1.2225077225845646 1.1003393370584018 1.1143910375426567 1.1585051951219703 1.1777742908722808 1.1354334508171606 0.9352816336355357 1.0490700773551727 0.88386908329956 1.0 15.777590533500272 -7.227978448349546 7.91218652669381 0.971163301968606 1.1492946794251255 0.7592270593288779 0.05085552706191367 0.13143794798345856 28.042168012023637 0.018745772640475868 0.014332902415674672 5.915909908595507e-08 7.227978448349546 0.17813137745651952 LQLGT(ph)PPPLLAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQLGTPPPLLAAR 13 0 Q9P2N5 Q9P2N5 RBM27 RNA-binding protein 27 1 LQLGT(1)PPPLLAAR 77.89399999999999 0.03816 21808000.0 34411.0 33820.0 32232.0 37848.0 38438.0 32746.0 36792.0 34370.0 31394.0 29027.0 True False 40236.10265176995 37177.42609140657 33000.53312054072 35727.499264871585 30906.349829491744 31028.742113961594 33306.79540898712 33467.82391802519 31853.07785838711 34289.36532239442 1.173428037336454 1.0842261366420203 0.9624130633583946 1.041941107073741 0.9013392210355896 0.9049086158995393 0.9713447623142333 0.976040927073308 0.9289491817331431 1.0 15.06547358056525 -4.720226877736139 1.0084726676728721 0.95058170554565 1.3180414668438223 0.753592362992141 0.040099299731688694 1.017842944394672 0.7663109243293748 0.013275525680092585 0.41881232431183046 1.904465555160053e-05 4.720226877736139 0.36745976129817226 LQLQGLDLS(ph)SR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LQLQGLDLSSR 11 0 P49454 P49454 CENPF Centromere protein F 1 LQLQGLDLS(0.967)S(0.033)R;LQLQGLDLS(0.905)S(0.095)R 164.22 0.00015894 5194900.0 24903.0 22411.0 24295.0 25686.0 27119.0 25620.0 25564.0 18526.2 22488.0 15278.4 True False 29118.586043329968 24635.8159708608 24874.284939300574 24246.896695135565 21805.22662537039 24276.44209856763 23142.392852667603 18039.906880131464 22816.844456883766 18048.252976252137 1.6133742186373472 1.3649972661219103 1.3782101221669554 1.343448406172032 1.2081627320972104 1.345085429072306 1.2822511343961283 0.9995375676453752 1.2642134663618763 1.0 14.139571574308512 -1.5228787452804302 0.1422927532415475 0.9485479879740479 3.022408578753156 0.7133057508006574 0.09254629715608813 39.900101175778424 0.37820810503185154 0.37370417943308115 16.878517525804366 0.0299999999999936 1.5228787452804302 2.073860590779108 LQLQGLDLS(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 1 LQLQGLDLSSR 11 0 P49454 P49454 CENPF Centromere protein F 1 LQLQGLDLS(0.5)S(0.5)R 148.89 0.00029502 2992800.0 18049.0 19415.0 21451.0 13237.0 17722.0 15389.0 11797.0 14131.0 14725.0 13686.0 True False 17791.61795021878 19370.045760354053 19687.381583254566 14210.493137337535 16679.626802792558 14730.848343511125 12407.790936835685 14787.577847751752 13066.515438875833 16051.606864551306 1.1084010529506645 1.2067356199167358 1.2265053430091524 0.8853003476381094 1.0391250510644006 0.917717987227997 0.7729936972377078 0.9212521819487705 0.8140316137278562 1.0 13.970430106771287 -5.76448360143592 24.999996068456944 0.9042646210342922 1.183166198158838 0.7180482297256188 0.07847262271652172 40.585973178822485 333308.02067754476 0.022544417468318912 0.03512012271226324 1.7199522838438471e-06 5.76448360143592 0.2789015771245458 LQLQGLDLSS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 LQLQGLDLSSR 11 0 P49454 P49454 CENPF Centromere protein F 1 LQLQGLDLS(0.027)S(0.973)R;LQLQGLDLS(0.021)S(0.979)R 168.89 0.00031299999999999996 6522000.0 19773.6 23117.0 27971.0 28103.0 26935.0 32282.0 22353.0 35556.0 28076.0 26570.0 True False 26061.19348356963 30589.118172426293 27600.086264073285 21624.28753702178 23195.540181942997 30263.401436765318 24342.37369650115 30061.637195597265 29560.040041709977 25639.79238727857 1.0164354332486774 1.1930329899084278 1.076455138449847 0.8433877782782235 0.9046695788945502 1.180329426215666 0.9493982372719544 1.1724602423267918 1.1528970123945494 1.0 14.646096959639634 -7.7713980147625525 24.99995355994488 1.122008960636043 1.0265000212486557 0.10318073585771648 0.11255957448659085 482.05602260289044 1210123.7438256505 0.0637592130925552 0.03120428058595057 1.692785714105919e-08 7.7713980147625525 -0.09550893938738736 LQLQGLDLSS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 LQLQGLDLSSR 11 0 P49454 P49454 CENPF Centromere protein F 1 LQLQGLDLS(0.469)S(0.531)R 145.83 0.00021400000000000002 3536800.0 18790.0 19767.0 19990.0 14128.0 13437.0 15658.0 14891.0 11141.0 13447.0 12937.0 True False 18522.05115433602 19721.230725980873 18346.49936363147 15167.020249626401 12646.662078158428 14988.343840580752 15661.983117777414 11658.651532220108 11932.457256812446 15173.143212531064 1.2207128671295469 1.2997459029908631 1.2091429644241163 0.9995964604815958 0.8334899302679692 0.9878206269220677 1.0322174448892456 0.7683741838402713 0.7864196026936443 1.0 13.889232359491878 -5.815069969322797 2.7999718152514466 0.9007799138988889 1.260538176959698 0.7607700653044691 0.08592095073319254 0.12953390654368824 2.0642341406777187 0.026902767101198568 0.04585238738967794 1.530840807561477e-06 5.815069969322797 0.35975826306080905 LQMEAPHIIVGTPGR ddPTM_PC-9_Lapatinib_30min_R1 2 LQMEAPHIIVGTPGR 15 0 P60842;P60842-2;J3KT12;J3QL43;J3QS69;J3KTB5;J3QR64;J3KS25;J3QLN6;J3QKZ9;J3KSZ0 P60842 EIF4A1 Eukaryotic initiation factor 4A-I 0 ; 85.988 0.0038123000000000007 13555500.0 60823.0 56809.0 67156.0 49372.0 63992.0 62172.0 55882.0 55747.0 51152.0 44879.0 False True 59955.65286642784 56677.462250834535 61634.692909656595 53002.981580163876 60228.116373112636 59513.04849001064 58775.29652727406 58337.20913442908 45390.7231055604 52636.275352491466 1.1390557645828927 1.0767757002424714 1.1709546790099616 1.0069667966666842 1.1442321093158774 1.1306470317564685 1.1166309951392108 1.1083080773432379 0.8623467903378519 1.0 15.683769784264587 -8.246604984051583 24.621829363315026 0.9311734085137783 1.1108973699898754 0.6556637709076804 0.052326539180495645 312.53881369110593 518748.31217854004 0.033118168696590164 0.012395910912933952 5.667545507143221e-09 8.246604984051583 0.17972396147609715 LQMES(ph)PDLPKPLSR ddPTM_PC-9_AZD4547_30min_R2 1 LQMESPDLPKPLSR 14 1 Q07002;Q07002-3;A0A0A0MSJ6;D6R9B0;D6RA44 Q07002 CDK18 Cyclin-dependent kinase 18 1 LQMES(1)PDLPKPLSR 64.275 0.019635 6731900.0 40629.0 37837.0 47067.0 68674.0 61831.0 69397.0 58517.0 53362.0 54070.0 65525.0 True False 53548.17686430139 50067.07030713736 46442.8608269685 52842.2703027234 53246.832930748766 65057.59461951559 63724.89963755011 45116.12903677191 56928.02981390725 63230.989694257776 0.8468660244482032 0.7918122197553412 0.7344952380396813 0.8357020909878655 0.8421002610937196 1.0288878117215947 1.0078112005787123 0.7135129349536191 0.9003185002982339 1.0 15.948344180364908 -6.534379954941606 24.563862429490797 0.9191057741222943 0.8019210156207656 0.3225605411898572 0.08769015881257183 253.20539189396754 540782.1436872139 0.030821376973178757 0.030847002164773648 2.921595218315155e-07 6.534379954941606 -0.11718475850152876 LQNAT(ph)PTNFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LQNATPTNFK 10 0 Q9NXF1-2;Q9NXF1 Q9NXF1-2 TEX10 Testis-expressed sequence 10 protein 1 LQNAT(0.999)PT(0.001)NFK;LQNAT(0.57)PT(0.43)NFK 126.5 0.00084142 13987900.0 102065.0 93538.0 93348.0 87074.0 103698.0 94285.0 96379.0 75366.0 87604.0 73631.0 True False 119342.58862436116 102823.83446889387 95573.77034426123 82195.52607771673 83379.12130232155 89340.5286207435 87249.28339646595 73387.72235687771 88885.04276951459 86979.71743732475 1.37207376777645 1.1821587549187655 1.0988052520764868 0.9449964715848223 0.9586041868025417 1.0271420884428588 1.0030991818217325 0.8437337406822335 1.0219053980436619 1.0 16.408391401613876 -4.858103142834543 1.0551332218691596 0.9647270480280666 1.5399976950627148 0.8470134622106007 0.05409696463303735 0.577306727253445 0.5713428718362914 0.017721275603771583 0.3642114181727768 1.3864265201899208e-05 4.858103142834543 0.5752706470346481 LQPFATEADVEEALR ddPTM_PC-9_Lapatinib_30min_R1 1 LQPFATEADVEEALR 15 0 P33992;B1AHB1 P33992 MCM5 DNA replication licensing factor MCM5;DNA helicase 0 88.22399999999999 0.032916 0.0 3102.5 2879.4 1065.1 2512.3 2910.3 3009.1 1119.1 1526.2 1546.8 1219.7 False True 3058.2577810711796 2872.732926209809 977.5315894048966 2697.0629227871204 2739.121875869947 2880.4078075547027 1177.0415222016454 1597.1128236670238 1372.583095473897 1430.523519851908 2.1378591394203568 2.0081689579680613 0.6833383553918033 1.885367758977027 1.9147688506047833 2.0135340437135145 0.8228047325803466 1.116453383326659 0.9594970487559622 1.0 10.482327502487296 -7.266290969478299 24.957574027517285 0.9843932139428686 1.7463979694662308 0.5020614224001809 0.38926841445046284 388.64801319105754 1999273.9312256281 0.16813357522707065 0.11746412483938276 5.4163788118854564e-08 7.266290969478299 0.7620047555233622 LQPGGSLNANTSNTIAS(ph)TSATTPVKK ddPTM_PC-9_AZD4547_30min_R2 1 LQPGGSLNANTSNTIASTSATTPVKK 26 1 O95171-2;O95171;O95171-3;F2Z2X8 O95171-2 SCEL Sciellin 1 LQPGGSLNANTSNTIAS(0.304)T(0.304)S(0.204)AT(0.094)T(0.094)PVKK 77.23100000000001 2.8128000000000002e-05 23742000.0 36916.0 39163.0 60452.0 57861.0 70321.0 70578.0 53928.0 62567.0 57313.0 64113.0 True False 48654.520099499125 51821.67387579406 59650.36698136492 44522.0403935387 60558.14297881612 66164.74650281959 58727.48752762112 52898.70779662883 60342.44817319149 61868.42338447845 0.7864192658852459 0.8376110306504931 0.964148813210747 0.7196246155629108 0.9788214999836079 1.0694429061436048 0.94923200422713 0.8550194897951781 0.9753351527676105 1.0 15.916915649247306 -6.30188461066836 24.86366607745387 0.9678624120680289 0.8375121691712257 0.4641049502524658 0.07559947192454412 495.42226616189157 304558.9916616484 0.024204880603956595 0.027446053943119633 4.990170555632382e-07 6.30188461066836 -0.1303502428968032 LQPGGSLNANTSNTIAST(ph)SATTPVKK ddPTM_PC-9_Lapatinib_30min_R1 1 LQPGGSLNANTSNTIASTSATTPVKK 26 1 O95171-2;O95171;O95171-3;F2Z2X8 O95171-2 SCEL Sciellin 1 LQPGGSLNANTSNTIAS(0.088)T(0.324)S(0.237)AT(0.175)T(0.175)PVKK 56.972 0.0034561999999999996 10570000.0 37621.0 34145.0 37393.0 28193.0 37990.0 32685.0 27016.0 36137.0 36910.0 25065.0 True False 37084.51764115357 34065.93935036254 34318.69188115418 30266.407269090963 35755.50289121371 31287.138742456373 28414.756289696776 37816.05694460442 32752.80712046907 29397.451852986887 1.2614874862831233 1.1588058557157332 1.1674036257556546 1.029558868586625 1.216278984655632 1.064280635577518 0.9665720835872288 1.286371932292566 1.1141376226845072 1.0 14.8434034884077 -4.266731832845624 1.0024753663443473 1.107022444646723 1.5360682258632563 0.21792067415767835 0.0925653678017444 7.861074604422381 3.1159460036944404 0.029588555270597935 4.650388640454303 5.410883297871795e-05 4.266731832845624 0.42904578121653336 LQPGGSLNANTSNTIASTSATT(ph)PVKK ddPTM_PC-9_Lapatinib_30min_R1 1 LQPGGSLNANTSNTIASTSATTPVKK 26 1 O95171-2;O95171;O95171-3;F2Z2X8 O95171-2 SCEL Sciellin 1 LQPGGSLNANTSNTIAS(0.196)T(0.196)S(0.054)AT(0.158)T(0.396)PVKK 90.869 3.8979999999999996e-07 11531000.0 52059.0 36794.0 45855.0 46130.0 48072.0 37642.0 34857.0 32747.0 42611.0 36677.0 True False 51316.62911354864 36708.80575361662 42084.97890541876 49522.5540851689 45244.49947318835 36032.13940778774 36661.72490338911 34268.54516880096 37811.700466277645 43016.570580969455 1.1929502612709701 0.8533643025893982 0.9783434229421618 1.1512436583468069 1.051792341000901 0.8376339378325145 0.8522698208677814 0.7966359174146109 0.8790031365960529 1.0 15.392604892617193 -6.7601357803684845 24.99818916311582 0.8590958696972121 1.0370018720483216 0.42335143314371904 0.09970564505775967 34.18464215715168 655537.9059476611 0.03385257842432652 0.032099659102806606 1.7372575974519116e-07 6.7601357803684845 0.17790600235110954 LQPLS(ph)PVPSDIEISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQPLSPVPSDIEISR 15 0 H0Y327;A0A087WVM4;B7ZM99;Q6UB35 H0Y327 MTHFD1L Monofunctional C1-tetrahydrofolate synthase, mitochondrial 1 LQPLS(1)PVPSDIEISR 96.163 0.01402 0.0 5805.9 5261.0 7444.8 7078.3 10614.0 8160.7 6555.9 6875.0 7068.4 5438.2 True False 6788.7241982479745 5783.277311262272 7622.312266561225 6681.725799158225 8534.26289323652 7732.738525908703 5934.877691394287 6694.538534664626 7171.761977900979 6424.1026112324835 1.0567583690799014 0.9002467210206552 1.186517826355028 1.0401025954154732 1.3284754945094497 1.2037071936534889 0.9238454069860603 1.042097074065923 1.1163834720449857 1.0 12.649279221653982 -11.001100038734048 14.091896784228899 0.9999999976627935 1.0888057285705581 0.04526136038175255 0.12218807766412161 1.6005483987321636e-08 5.261043183057809e-10 0.1243830471411353 0.030167318958479152 9.97470272376797e-12 11.001100038734048 0.08880573090776467 LQPQEIS(ph)PPPTANLDR ddPTM_PC-9_AZD4547_30min_R2 4 LQPQEISPPPTANLDR 16 0 H0YBP1;E7ESA6;Q05397-7;Q05397;Q05397-5;E9PEI4;H0YB16;H0YBZ1;Q05397-2;B4DWJ1;Q05397-6 H0YBP1 PTK2 Focal adhesion kinase 1 1 LQPQEIS(0.998)PPPT(0.002)ANLDR;LQPQEIS(0.952)PPPT(0.048)ANLDR;LQPQEIS(0.984)PPPT(0.016)ANLDR;LQPQEIS(0.972)PPPT(0.028)ANLDR 102.5 0.0014922000000000002 181082900.0 61743.6 62026.0 76286.6 109320.1 93765.3 79169.8 69436.1 82086.8 68541.0 70623.5 True False 81376.7804533382 82074.69151546113 75274.98983922102 84118.03992370833 80747.60660189112 74219.29989060241 75615.77838445062 69402.17122700956 72163.93733077521 68150.99276112037 1.1940659579028619 1.2043066166790182 1.1045325502897858 1.234289282014642 1.18483390087836 1.0890420943793495 1.1095330430401134 1.01835891767967 1.0588831417866622 1.0 16.0564470525904 -7.268945528022162 1.0523183629617292 1.0211119633677812 1.1857757819386512 0.7499841335496438 0.03861202455082206 0.2661808909055529 0.5722453579506448 0.027493947264211702 0.015527730869022628 5.3833729997218963e-08 7.268945528022162 0.16466381857086998 LQPQEIS(ph)PPPTANLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LQPQEISPPPTANLDR 16 0 H0YBP1;E7ESA6;Q05397-7;Q05397;Q05397-5;E9PEI4;H0YB16;H0YBZ1;Q05397-2;B4DWJ1;Q05397-6 H0YBP1 PTK2 Focal adhesion kinase 1 1 LQPQEIS(0.994)PPPT(0.006)ANLDR;LQPQEIS(0.998)PPPT(0.002)ANLDR;LQPQEIS(0.999)PPPT(0.001)ANLDR;LQPQEIS(0.985)PPPT(0.015)ANLDR 164.01 4.5767e-05 111233500.0 70598.8 84285.6 86671.6 94261.0 112540.0 95080.0 102805.0 97355.0 83447.7 74626.3 True False 82549.78245014015 92652.91734387513 88738.17964787348 88979.86176828509 90488.59487514947 90093.83742122604 93066.56615625478 94799.53440614903 84667.9647449619 88155.45744853423 0.9364114808017789 1.051017373461723 1.0066101659069655 1.0093517105305947 1.0264661711724126 1.021988201624652 1.055709638970312 1.0753677327520381 0.9604392875437308 1.0 16.427762264922706 -4.751198670165906 24.978951679588175 1.0255107642003243 0.936411295588411 0.4115632950021606 0.03092740578133936 413.0485408492923 1007432.1771809766 0.007489896561298152 0.10186344808689596 1.7733780547174412e-05 4.751198670165906 -0.08909946861191331 LQPQEIS(ph)PPPTANLDR ddPTM_PC-9_Lapatinib_30min_R1 2 LQPQEISPPPTANLDR 16 0 H0YBP1;E7ESA6;Q05397-7;Q05397;Q05397-5;E9PEI4;H0YB16;H0YBZ1;Q05397-2;B4DWJ1;Q05397-6 H0YBP1 PTK2 Focal adhesion kinase 1 1 LQPQEIS(0.998)PPPT(0.002)ANLDR;LQPQEIS(0.99)PPPT(0.01)ANLDR 101.5 0.0016297 136807000.0 45935.0 43491.0 49801.0 44443.0 50545.0 53448.0 50884.0 48220.0 58681.0 44834.0 True False 45279.95847655268 43390.29926157907 45706.55401741929 47711.48647750184 47572.042475293405 51162.153633373346 53518.52454267586 50460.4772357646 52071.72784167554 52583.497162450156 0.8611058776989651 0.8251695228168289 0.8692186043886466 0.9073471536155756 0.9046952949577605 0.9729697793837153 1.0177817648251324 0.9596257373273073 0.9902674917342685 1.0 15.682322473790412 -6.35024388979821 0.9792775109027736 0.9929604279656857 0.8426102966378745 0.8942240490758123 0.020450582957940375 0.16677666272107805 0.34162140386968354 0.010162649695389232 0.014433737428614347 4.464328153350561e-07 6.35024388979821 -0.15035013132781128 LQPSS(ph)SPENSLDPFPPR ddPTM_PC-9_AZD4547_30min_R2 1 LQPSSSPENSLDPFPPR 17 0 H3BUF6;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 LQPS(0.172)S(0.574)S(0.239)PENS(0.014)LDPFPPR 161.94 3.0657e-05 20262000.0 22607.0 24440.0 30439.0 42478.0 42037.0 33356.0 28043.0 33781.0 28076.0 32352.0 True False 29795.555745188456 32339.75204975122 30035.358971510715 32685.353378557866 36200.88816143819 31270.24404698422 30538.77267351059 28560.922660154996 29560.040041709977 31219.366327182415 0.9543933542060955 1.0358875228544693 0.9620745871885044 1.0469576171409676 1.1595651167947765 1.0016296845768295 0.978199632672261 0.914846328424266 0.9468494565814528 1.0 14.93015363416478 -7.284834548783283 3.2141210088049443 0.9495529618758641 1.0322211318975507 0.25564789884722017 0.05659214245784477 0.3430910104496462 7.311680925817771 0.026597940531263412 0.01795090091160239 5.189977215006349e-08 7.284834548783283 0.08266817002168658 LQPSS(ph)SPENSLDPFPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LQPSSSPENSLDPFPPR 17 0 H3BUF6;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 LQPS(0.181)S(0.639)S(0.181)PENSLDPFPPR;LQPS(0.003)S(0.498)S(0.498)PENSLDPFPPR 333.03 2.0336999999999993e-189 24521000.0 31536.5 31769.1 35801.6 38927.9 42397.4 33049.0 38320.7 32244.1 33998.5 28811.1 True False 36875.00657573286 34922.926293332486 36655.24592232411 36746.89596895462 34089.933822282495 31315.852260560583 34690.68587815757 31397.726540447933 34495.66374365718 34034.324361457875 1.0834652154132935 1.0261089928637135 1.0770081854139668 1.0797010564595955 1.0016339228666338 0.9201255746397063 1.0192852812275301 0.9225312131068554 1.0135551209214466 1.0 15.054702849643741 -6.415067497224617 4.48092838666916 0.971889477922419 1.0638668808373235 0.6029513042050206 0.03497781378170212 0.14780213831502093 4.854838542061138 0.01042939441847892 0.011786197589931094 3.845320141646994e-07 6.415067497224617 0.09197740291490453 LQPSS(ph)SPENSLDPFPPR ddPTM_PC-9_Lapatinib_30min_R1 3 LQPSSSPENSLDPFPPR 17 0 H3BUF6;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 LQPS(0.029)S(0.902)S(0.048)PENS(0.02)LDPFPPR;LQPS(0.21)S(0.711)S(0.079)PENSLDPFPPR;LQPS(0.006)S(0.755)S(0.239)PENSLDPFPPR 271.27 4.756899999999999e-70 118355000.0 235228.0 190638.0 243018.0 195808.0 207690.0 215112.0 173130.0 177984.0 230157.0 172119.0 True False 231873.60558446826 190196.58942376403 223037.99811660787 210208.3735163396 195474.0825342505 205912.16121056397 182093.82426840387 186253.78640253659 204234.29499934413 201869.53981584907 1.148630971249995 0.9421757715268315 1.1048620724061156 1.0413080334363345 0.9683188593611861 1.0200259107857614 0.9020371495100987 0.9226443304544232 1.011714274405402 1.0 17.6230637126353 -6.235118715729378 3.6524998497599457 0.9650364915785812 1.0559601232600317 0.34121860883845156 0.060127522468523244 0.2770721722714658 8.012177510292975 0.01823015638132583 0.023013794382814114 5.819441198159009e-07 6.235118715729378 0.09092363168145057 LQPSSS(ph)PENSLDPFPPR ddPTM_PC-9_AZD4547_30min_R2 3 LQPSSSPENSLDPFPPR 17 0 H3BUF6;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 LQPS(0.001)S(0.003)S(0.892)PENS(0.103)LDPFPPR;LQPS(0.031)S(0.102)S(0.866)PENS(0.001)LDPFPPR;LQPS(0.059)S(0.086)S(0.855)PENSLDPFPPR 218.83 1.401e-22 153830000.0 150378.0 142172.0 211313.0 301465.0 253370.0 231250.0 166093.0 255093.0 181295.0 214452.0 True False 198195.0759432896 188126.3186750093 208510.8515505388 231966.90183782091 218193.94898455124 216789.90094331172 180874.95523522422 215674.2383039854 190877.88357892196 206944.1007541089 0.957722762915504 0.9090682845728524 1.0075708889053645 1.1209157496760158 1.0543617730075303 1.0475771000638554 0.8740280808977491 1.0421859696317202 0.9223644592107662 1.0 17.658881597447646 -10.444437850550756 17.950148642043253 0.999994059539916 0.9959733592326944 0.0 0.07297765626626483 0.0 0.0 0.07442040739777055 0.01804960002367682 3.5938682290964324e-11 10.444437850550756 -0.004020700307221681 LQPSSS(ph)PENSLDPFPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LQPSSSPENSLDPFPPR 17 0 H3BUF6;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 LQPS(0.043)S(0.132)S(0.785)PENS(0.039)LDPFPPR;LQPS(0.01)S(0.035)S(0.955)PENSLDPFPPR;LQPSS(0.078)S(0.921)PENSLDPFPPR;LQPS(0.006)S(0.067)S(0.903)PENS(0.024)LDPFPPR 268.42 1.6322999999999997e-69 97676600.0 145535.0 147431.8 166363.5 164478.0 193236.7 171687.2 166258.8 159980.1 152760.9 119012.3 True False 170171.2010527259 162067.85476117747 170330.23677708683 155262.8309048706 155373.35579625747 162683.62099395783 150509.56285452537 155780.79188792693 154994.7391672702 140588.28788915192 1.2104223161668979 1.1527834728947073 1.2115535321931312 1.10437955562336 1.1051657156445562 1.1571633984349192 1.0705697118468074 1.1080637955471346 1.1024726276592625 1.0 17.101116886001982 -1.5228787457286241 0.0533268694485913 0.7810370392990796 1.7835656122894548 0.7390540055217653 0.030954808745721762 219.81274800090537 0.8853242117144293 3.7336497828529702 17.752353463045868 0.02999999996903346 1.5228787457286241 1.002528572990375 LQPSSS(ph)PENSLDPFPPR ddPTM_PC-9_Lapatinib_30min_R1 1 LQPSSSPENSLDPFPPR 17 0 H3BUF6;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 LQPSS(0.002)S(0.998)PENSLDPFPPR 278.19 7.575899999999998e-83 19448000.0 63819.0 57568.0 60910.0 58744.0 64661.0 57872.0 53794.0 61156.0 61591.0 50104.0 True False 62908.92935702876 57434.70483296739 55902.21491939936 63064.229724239354 60857.7671084172 55396.94946622107 56579.190103936475 63997.531020954404 54653.97299801709 58764.40964061659 1.0705277180824015 0.9773722765908612 0.9512937381874258 1.0731704803965363 1.0356228792325641 0.9426955840279895 0.9628138944976358 1.0890525645087192 0.9300522770885038 1.0 15.842655038342764 LQPSSSPENS(ph)LDPFPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQPSSSPENSLDPFPPR 17 0 H3BUF6;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 LQPS(0.005)S(0.015)S(0.048)PENS(0.932)LDPFPPR 87.21600000000001 0.0029331 2708700.0 4377.6 7596.7 9322.3 7221.6 8656.4 8134.5 9295.1 7912.1 7075.4 5678.8 True False 5118.641218458871 8350.850171158725 9544.578987019622 6816.997164743091 6960.240560487341 7707.912500031162 8414.60083730366 7704.41575856291 7178.864339658284 6708.321486643937 0.7630286098616367 1.2448494288452057 1.42279689576932 1.016200129691984 1.03755322018257 1.1490076191752856 1.2543526505187437 1.1484863648681964 1.0701431578601568 1.0 12.711736114302733 -8.50662851342028 3.2489195827003132 1.0007946289952323 1.140745898529419 0.05430849993698117 0.16502943273088344 0.6650108173384917 17.170665405629627 0.1597465164069271 0.04239757061691455 3.1143791740539935e-09 8.50662851342028 0.13995126953418668 LQQGAGLES(ph)PQGQPEPGAAS(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 2 LQQGAGLESPQGQPEPGAASPQR 23 0 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 2 LQQGAGLES(1)PQGQPEPGAAS(1)PQR;LQQGAGLES(1)PQGQPEPGAAS(1)PQR 139.22 1.3016e-06 21582000.0 46367.0 38211.0 50793.0 58973.0 51954.0 58647.0 47052.0 67568.0 51896.0 55111.0 True False 61110.74150648707 50561.958493168706 50119.451632443386 45377.68597376741 44741.083891318616 54979.79381890759 51239.536848198084 57126.91815817631 54639.11661221619 53181.58066448286 1.1490959979551656 0.9507419272127114 0.9424212482258071 0.85325944446914 0.841289095440497 1.0338127060526738 0.9634827736968381 1.0741861645403918 1.0274067812487329 1.0 15.698639037206126 LQQGAGLES(ph)PQGQPEPGAAS(ph)PQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQQGAGLESPQGQPEPGAASPQR 23 0 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 2 LQQGAGLES(1)PQGQPEPGAAS(1)PQR 114.76 6.9055e-05 0.0 8683.9 9900.3 9864.9 9181.8 9553.2 7930.2 11136.0 10709.0 7946.8 6814.1 True False 10153.912755156936 10883.136355196699 10100.116628841584 8667.373513797238 7681.319038220011 7514.326351680763 10081.117462341834 10427.90009712341 8063.006916131443 8049.4423896140825 1.2614429998602361 1.352036057707405 1.2547597883144572 1.0767669478547297 0.9542672232962313 0.9335213531531374 1.252399479912938 1.2954810522748967 1.0016851510776525 1.0 12.97467313129286 -5.68440820356685 4.174360553087668 1.0820676672361735 1.3052229392406898 0.43061233338643956 0.1143163952950838 0.23227189566028922 7.683181446637338 0.03517578278941249 0.06229307414021167 2.0681964885498272e-06 5.68440820356685 0.22315527200451624 LQQGAGLES(ph)PQGQPEPGAAS(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 2 LQQGAGLESPQGQPEPGAASPQR 23 0 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 2 LQQGAGLES(1)PQGQPEPGAAS(1)PQR;LQQGAGLES(1)PQGQPEPGAAS(1)PQR 141.3 9.724400000000001e-06 26416000.0 41796.0 43409.0 49820.0 43983.0 48820.0 49418.0 43049.0 39555.0 59787.0 38379.0 True False 41199.98137555231 43308.489127541 45723.99191076137 47217.65654298684 45948.503583812955 47304.507338984506 45277.86657962526 41392.86970262688 53053.15847497926 45012.759013197036 0.915295624591088 0.9621380710043484 1.0158006954729393 1.0489838343200284 1.0207884295726368 1.0509133049390633 1.0058896093516618 0.9195808168633062 1.178624897430191 1.0 15.458046375569666 -5.064405991437642 2.084407170676757 1.0283964856742027 0.9111630068375484 0.2829398837463589 0.06064948061907614 0.5439187051690826 3.8780764991780234 0.015872467753655153 0.09662733118170237 8.621721866399132e-06 5.064405991437642 -0.11723347883665436 LQQGAGLESPQGQPEPGAAS(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 2 LQQGAGLESPQGQPEPGAASPQR 23 0 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 LQQGAGLESPQGQPEPGAAS(1)PQR;LQQGAGLESPQGQPEPGAAS(1)PQR 120.4 8.7933e-09 95942000.0 104528.0 112692.0 156773.0 174483.0 160146.0 177976.0 152595.0 159558.0 141914.0 145041.0 True False 137765.72968253432 149117.48518783014 154694.08758634148 134258.64008547761 137912.4922211788 166847.132585024 166175.6593843146 134901.97737808258 149415.2843168268 139963.15873704426 0.9842999466835529 1.0654052575934254 1.1052486167232976 0.9592427128464284 0.985348526466753 1.1920789305597768 1.1872814309408168 0.9638391887934569 1.0675329541364575 1.0 17.094687603736 LQQGAGLESPQGQPEPGAAS(ph)PQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LQQGAGLESPQGQPEPGAASPQR 23 0 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 LQQGAGLESPQGQPEPGAAS(1)PQR;LQQGAGLESPQGQPEPGAAS(1)PQR;LQQGAGLESPQGQPEPGAAS(1)PQR 129.93 3.2936e-07 109505000.0 114605.0 134596.0 171626.0 157056.0 161674.0 121937.0 154445.0 145876.0 122795.0 114337.0 True False 134005.36294807165 147957.8013660249 175718.21473522994 148256.66150242212 129995.14028651956 115542.40906217952 139814.85151503098 142046.90956839823 124590.64456968378 135065.39300880602 0.9921517271218006 1.0954530843913388 1.3009862172745719 1.0976657913604566 0.9624607561616032 0.8554553204805495 1.0351641408685297 1.0516898992707706 0.9224468370040628 1.0 17.043298543398564 -6.188376090603282 4.792777819118239 0.9712119512291874 1.1358647411020417 0.41289676713604573 0.08793358719804764 0.2256121901580994 9.7836946524803 0.027835673137134916 0.03609909441331495 6.480729718440046e-07 6.188376090603282 0.16465278987285437 LQQGAGLESPQGQPEPGAAS(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 1 LQQGAGLESPQGQPEPGAASPQR 23 0 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 LQQGAGLESPQGQPEPGAAS(1)PQR 114.8 1.9361e-08 60905000.0 59637.0 61363.0 75159.0 59776.0 69419.0 65801.0 65659.0 59028.0 71289.0 67497.0 True False 58786.5654439136 61220.91774363146 68979.71714213002 64172.126446890405 65335.91090300515 62986.84461962289 69058.50174804557 61770.65637230843 63259.68211354976 79163.76651590096 0.7425943462670593 0.7733451860370303 0.8713546636045246 0.8106249774510247 0.8253259512340367 0.7956524479791048 0.8723498740320089 0.7802895073202597 0.7990989425805468 1.0 16.27255263524639 -11.492617994515395 2.7080461858663294 1.1573045537556022 0.8100250085350182 0.6889631794506703 0.038707424839381714 7875471.995641496 5095304.122769315 7777307.025579043 0.00988554723937826 3.2164885184450506e-12 11.492617994515395 -0.3472795452205839 LQQGAGLESPQGQPEPGAAS(ph)PQRQQDLHLESPQR ddPTM_PC-9_AZD4547_30min_R2 2 LQQGAGLESPQGQPEPGAASPQRQQDLHLESPQR 34 1 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 LQQGAGLESPQGQPEPGAAS(0.994)PQRQQDLHLES(0.005)PQR;LQQGAGLES(0.002)PQGQPEPGAAS(0.984)PQRQQDLHLES(0.014)PQR 75.758 2.2858000000000002e-08 84031000.0 24013.6 15369.8 51334.0 98945.0 71804.0 50294.0 33630.1 54483.0 35142.0 50198.0 True False 31649.425286090915 20337.78727717946 50653.27761896022 76134.7589350113 61835.25402725952 47149.108229374746 36623.11374986368 46063.90424478921 36999.534376185096 48440.58329908207 0.6533658996358671 0.41985017297603133 1.0456785234442063 1.5717143302123289 1.2765175358330434 0.9733389859958231 0.7560419643121364 0.9509362007550827 0.7638127342055814 1.0 15.563928616952179 -5.270454728696464 23.923144472920786 1.0550953887947938 0.536608040173002 0.4310932676089161 0.2319749313702801 324.1971146272357 860293.7394377041 0.06849935416344832 0.14622623332773738 5.364697906885335e-06 5.270454728696464 -0.5184873486217918 LQQGAGLESPQGQPEPGAAS(ph)PQRQQDLHLESPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LQQGAGLESPQGQPEPGAASPQRQQDLHLESPQR 34 1 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 LQQGAGLES(0.006)PQGQPEPGAAS(0.902)PQRQQDLHLES(0.092)PQR;LQQGAGLES(0.002)PQGQPEPGAAS(0.877)PQRQQDLHLES(0.121)PQR 54.647 0.00043396 28212700.0 14669.3 7346.8 19311.0 33421.0 25567.4 35176.0 23645.1 36635.0 38863.0 20109.3 True False 17152.522758118317 8076.141750690294 19771.44747737534 31548.52972234392 20557.651507116585 33331.30863619107 21405.264952300542 35673.37006799106 39431.297853427364 23754.956904868784 0.7220607819584282 0.33997711648279266 0.8323082865001119 1.3280819598488842 0.8654047064553132 1.4031306716182477 0.9010862464630844 1.501723207112175 1.6599187281769212 1.0 14.535940969030747 -5.570084608104062 3.8067223218544126 1.2341840890599598 0.5344164547574427 0.5518294577443515 0.25889964821565525 0.1581132853619577 4.780333840941046 0.07185643937535897 0.13762311761807297 2.6910104972980044e-06 5.570084608104062 -0.6997676343025171 LQQGAGLESPQGQPEPGAAS(ph)PQRQQDLHLESPQR ddPTM_PC-9_Lapatinib_30min_R1 2 LQQGAGLESPQGQPEPGAASPQRQQDLHLESPQR 34 1 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 LQQGAGLES(0.031)PQGQPEPGAAS(0.929)PQRQQDLHLES(0.04)PQR;LQQGAGLES(0.006)PQGQPEPGAAS(0.99)PQRQQDLHLES(0.004)PQR 57.427 0.0003103 51791000.0 105187.0 39783.0 72799.0 54802.0 48538.0 47629.0 34187.0 29774.0 73791.0 36353.0 True False 103687.01409106657 39690.88490776022 66813.74723226661 58832.32189411288 45683.090269379594 45592.01869862181 35957.03558172429 31157.408735330875 65479.88052632168 42636.56761267232 2.431879954151117 0.9309118235859917 1.5670526727017402 1.3798559590577104 1.0714532812393134 1.069317284468065 0.8433379513185119 0.730767284514487 1.5357681021879428 1.0 15.379803680510221 -4.756193407401197 24.992896347693925 1.126474264638156 2.43188199661243 0.6799431839752714 0.2689085898446493 101.11416132135672 481675.87856149604 0.06954640324224463 0.5765421009383573 1.753099607856091e-05 4.756193407401197 1.305407731974274 LQQQAALS(ph)PTTAPAVSSVSK ddPTM_PC-9_AZD4547_30min_R2 1 LQQQAALSPTTAPAVSSVSK 20 0 A0A0U1RRM1;Q8WXI9;A0A0U1RR30 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 LQQQAALS(0.733)PT(0.197)T(0.07)APAVSSVSK 142.23 0.00023413 22297000.0 64737.0 60627.0 86520.0 109750.0 113600.0 95567.0 78200.0 121530.0 102520.0 72384.0 True False 85322.01938675022 80223.49212439718 85372.68826883631 84448.83312059725 97828.60087873491 89591.18038248399 85159.64850652662 102750.33098157635 107938.99790127197 69849.85819197485 1.2215059786127525 1.1485133141417625 1.222231375677222 1.2090050761234 1.4005554687006447 1.2826250861705721 1.2191814086790906 1.4710170305454031 1.5453001723298163 1.0 16.091969566251585 -6.1746394802181905 6.835194000250064 1.3362506225043227 1.1968618029984108 0.14070053531358362 0.141181180460234 0.45881593823349964 30.811455406156863 0.04132240925052339 0.05352708827243488 6.688989585630699e-07 6.1746394802181905 -0.13938881950591187 LQQQAALS(ph)PTTAPAVSSVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQQQAALSPTTAPAVSSVSK 20 0 A0A0U1RRM1;Q8WXI9;A0A0U1RR30 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 LQQQAALS(0.809)PT(0.145)T(0.046)APAVSSVSK 118.44 1.4723e-05 13254000.0 37612.0 33934.0 42160.0 48627.0 40721.0 43961.0 44302.0 34430.0 38932.0 36099.0 True False 43978.9687291381 37302.743258006805 43165.25429269039 45902.5868408611 32742.012368144384 41655.607771082454 40105.39384129558 33526.248981600445 39501.30684789216 42643.46294047324 1.0313179487915678 0.8747587715865938 1.0122361392869412 1.0764272804236683 0.7678084777929395 0.9768345462288147 0.9404816371803436 0.7861990248868936 0.9263156442766558 1.0 15.38003697909562 -6.245406565140115 24.995036101723706 0.8948216494092228 0.9908010837550156 0.24427052094630441 0.08467306763469681 1263.1841372093131 1969294.1596471183 0.024717110366958023 0.03180421826439475 5.683206478873773e-07 6.245406565140115 0.09597943434579281 LQQQAALS(ph)PTTAPAVSSVSK ddPTM_PC-9_Lapatinib_30min_R1 3 LQQQAALSPTTAPAVSSVSK 20 0 A0A0U1RRM1;Q8WXI9;A0A0U1RR30 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 LQQQAALS(0.788)PT(0.157)T(0.055)APAVSSVSK;LQQQAALS(0.567)PT(0.165)T(0.267)APAVSSVSK;LQQQAALS(0.412)PT(0.291)T(0.291)APAVS(0.003)S(0.003)VSK 120.75 0.00018213 23541700.0 170025.0 147195.0 175452.0 130353.0 173142.0 173343.0 180586.0 170436.0 187768.0 151021.0 True False 167600.41232123337 146854.17902113375 161027.01382430544 139939.59446486062 162958.12797026927 165929.52397226906 189935.85946591574 178355.07876720832 166619.59055530294 177124.77862716626 0.946227928244975 0.8291001414898039 0.9091162460293297 0.7900622123538258 0.9200188095268326 0.9367945312808981 1.07232799915429 1.0069459516030321 0.9406904660472383 1.0 17.434406524482355 -6.835900244960135 2.5000236296788407 1.0047829026779653 0.8694100275217208 0.5692218166623186 0.051487049824874585 0.1963637772418616 2.5052073951506078 0.019465248516444295 0.017214674374452933 1.4591493803265363e-07 6.835900244960135 -0.13537287515624452 LQQQAALSPT(ph)TAPAVSSVSK ddPTM_PC-9_AZD4547_30min_R2 1 LQQQAALSPTTAPAVSSVSK 20 0 A0A0U1RRM1;Q8WXI9;A0A0U1RR30 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 LQQQAALS(0.477)PT(0.485)T(0.038)APAVSSVSK 189.15 1.9705e-11 22804000.0 81115.0 65118.0 98297.0 138380.0 133600.0 107520.0 84766.0 124500.0 77635.0 98751.0 True False 106907.88270318766 86166.12004810553 96993.5175538811 106478.62894968787 115051.94610386419 100796.7574029183 92310.0097864993 105261.38572538705 81738.62760500626 95293.75754746489 1.1218770825564086 0.9042157877465061 1.017837055124724 1.117372550837361 1.2073397992156825 1.0577477475658614 0.9686889483869978 1.1045989625601382 0.8577542717243891 1.0 16.540094089484377 -7.183995390212227 6.313129483541278 0.9916557716929723 1.069902681411296 0.1777907881871541 0.0923945890589148 0.5238364227820017 34.7175081816447 0.037449382882089606 0.028850065398967062 6.546431226930861e-08 7.183995390212227 0.07824690971832371 LQQQAALSPT(ph)TAPAVSSVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQQQAALSPTTAPAVSSVSK 20 0 A0A0U1RRM1;Q8WXI9;A0A0U1RR30 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 LQQQAALS(0.226)PT(0.467)T(0.307)APAVSSVSK 180.03 2.6443e-09 9767200.0 66073.0 62077.0 63667.0 68726.0 73214.0 68664.0 69319.0 56081.0 68314.0 45587.0 True False 77257.85389876494 68239.59430739946 65185.06273844205 64875.50503269825 58868.242271096635 65063.138963936355 62752.602493900245 54608.93317273118 69312.96301260921 53851.56223350655 1.4346446174349785 1.2671794740420854 1.210458156363081 1.2047098049150482 1.0931575581008623 1.2081940851003565 1.1652884315927134 1.01406404768613 1.2871114622833086 1.0 15.716700577500744 -1.5228787453038366 0.5194991755457435 1.1245259933318206 12.15745852874449 0.5737114060270397 0.08081926139214606 82.495268281149 0.8293031888351265 0.03998696718713546 1002.5914846718947 0.029999999998376745 1.5228787453038366 11.03293253541267 LQQQAALSPT(ph)TAPAVSSVSK ddPTM_PC-9_Lapatinib_30min_R1 1 LQQQAALSPTTAPAVSSVSK 20 0 A0A0U1RRM1;Q8WXI9;A0A0U1RR30 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 LQQQAALS(0.006)PT(0.493)T(0.493)APAVS(0.007)S(0.001)VSK 87.18 0.0018050999999999998 6419600.0 9615.2 5868.9 8464.4 7679.7 6506.7 9386.7 10021.0 8461.5 9373.2 7519.7 True False 9478.085484788278 5855.3109226341385 7768.489705528881 8244.490756728197 6123.98869866439 8985.252722466426 10539.838346870421 8854.652180224433 8317.491511828252 8819.470125629581 1.0746774295708248 0.6639073367478701 0.8808340631432576 0.9348056787186703 0.6943714998101688 1.0187973420710477 1.195064805111297 1.0039891347318715 0.9430829055883336 1.0 13.106476265831498 -6.912199047047419 9.35001451842296 1.0459264527346188 0.846155631808619 0.34972166195421706 0.12419273921741436 0.32127956267800273 31.184935291679082 0.04253679594323369 0.03751749131925488 1.2240550583851714e-07 6.912199047047419 -0.19977082092599985 LQQQAALSPTT(ph)APAVSSVSK ddPTM_PC-9_Lapatinib_30min_R1 1 LQQQAALSPTTAPAVSSVSK 20 0 A0A0U1RRM1;Q8WXI9;A0A0U1RR30 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 LQQQAALS(0.279)PT(0.279)T(0.44)APAVS(0.001)SVSK 105.38 0.00035281 16588000.0 78059.0 70945.0 76215.0 65820.0 92234.0 77803.0 74992.0 70850.0 88984.0 70734.0 True False 76945.86434573251 70780.7312113479 69948.89689840801 70660.62236908346 86808.97745902097 74475.54705765132 78874.71882132592 74141.94965064117 78961.68487693895 82960.27765286944 0.9275024930328339 0.8531882150577605 0.8431613162035821 0.8517404276869539 1.0463920796197868 0.897725383336821 0.9507528307868168 0.8937042130074976 0.951801116280471 1.0 16.34013310214499 -6.155819003042922 21.074991619776714 0.9482902365071126 0.8659336420137964 0.444841283252291 0.04746273612120891 9.173516319781442 1822.2693125031578 0.013694742777775803 0.0176798786925608 6.985234606852778e-07 6.155819003042922 -0.08235659449331623 LQQTVPADAS(ph)PDSK ddPTM_PC-9_AZD4547_30min_R2 1 LQQTVPADASPDSK 14 0 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 LQQT(0.038)VPADAS(0.741)PDS(0.221)K 169.15 0.00032165 9210500.0 43175.0 48352.0 44810.0 38412.0 41419.0 53148.0 52310.0 48921.0 49724.0 41966.0 True False 56903.75190421162 63980.838425105154 44215.790121666134 29556.706859484082 35668.68679398169 49824.64715820591 56965.48866210245 41361.383542744225 52352.309126442036 40496.78311345627 1.4051425206982338 1.5798992785638224 1.0918346278960145 0.7298532028254604 0.8807782755003494 1.230335926155334 1.4066670061794107 1.0213498545517967 1.2927522904664102 1.0 15.305519690742054 -5.270733491180761 22.99118438639766 1.0796320114895663 1.492520897609459 0.4271360424780224 0.19029681929792058 199.5410174686653 493616.01006544224 0.054672527507186396 0.1167373245247955 5.361255549851127e-06 5.270733491180761 0.4128888861198927 LQQTVPADAS(ph)PDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LQQTVPADASPDSK 14 0 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 LQQTVPADAS(0.964)PDS(0.036)K;LQQT(0.003)VPADAS(0.988)PDS(0.009)K 163.9 2.6362e-13 4038200.0 42386.0 60654.0 51917.0 51903.0 50546.0 36828.0 53179.0 39213.0 38457.0 35262.0 True False 49561.112638340084 66675.3282716786 53154.898176318944 48995.04318179637 40641.87414749704 34896.674848011295 48141.500137381125 38183.70029960784 39019.360871503886 41654.7214661616 1.189807803146668 1.6006667653711861 1.2760833899585564 1.176218240268338 0.9756846935229814 0.8377603695264116 1.155727332770406 0.9166716030168761 0.9367332080998654 1.0 15.346192410548698 -5.92276844032598 2.018138176624415 0.9687592372389935 1.3963172444926428 0.6702797912237892 0.12217579955607932 0.17765306473954812 1.4682007304168119 0.037267039049090005 0.06313833948511095 1.1946248917787739e-06 5.92276844032598 0.42755800725364934 LQQTVPADAS(ph)PDSK ddPTM_PC-9_Lapatinib_30min_R1 1 LQQTVPADASPDSK 14 0 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 LQQT(0.002)VPADAS(0.537)PDS(0.461)K 120.59 8.453200000000001e-05 12484000.0 52013.0 58852.0 50574.0 54356.0 66436.0 52742.0 57192.0 65468.0 57254.0 39180.0 True False 51271.285081984 58715.73180985608 46416.00094128556 58353.52156630043 62528.365098201444 50486.34760760697 60153.121917394776 68509.88228268424 50805.45160865173 45952.210795931605 1.1157523042726667 1.2777564080780743 1.0100928799141697 1.2698740834351059 1.360725937123735 1.0986707001282472 1.309036515882288 1.4908941505976419 1.1056149579891337 1.0 15.487846651892943 LQQTVPADAS(ph)PDSKCPICLDR ddPTM_PC-9_AZD4547_30min_R2 2 LQQTVPADASPDSKCPICLDR 21 1 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 LQQT(0.414)VPADAS(0.518)PDS(0.068)KCPICLDR;LQQT(0.001)VPADAS(0.853)PDS(0.146)KCPICLDR 78.645 0.0037913000000000005 12932000.0 51765.0 41093.0 56075.0 58126.0 55515.0 62042.0 51309.0 65171.0 49473.0 57719.0 True False 68225.19322111193 54375.508632587014 55331.40886124587 44725.94873774788 47807.700508652924 58162.50393221594 55875.401601296355 55100.319430595926 52088.04177886873 55698.27537829626 1.2249067454554794 0.9762512081976477 0.9934133235803322 0.8030041941868827 0.858333587242128 1.0442424570093585 1.003180102468112 0.9892643723052629 0.9351823090588129 1.0 15.765345036707227 -4.724641302191905 3.1836612529403747 0.950358876311255 1.288462474923943 0.576979122334405 0.0692562733224947 0.3623972459613737 4.851331032179244 0.01927184544017418 0.3302865820969592 1.8852054986306807e-05 4.724641302191905 0.338103598612688 LQQTVPADAS(ph)PDSKCPICLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LQQTVPADASPDSKCPICLDR 21 1 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 LQQT(0.005)VPADAS(0.994)PDS(0.001)KCPICLDR;LQQT(0.036)VPADAS(0.958)PDS(0.006)KCPICLDR 53.481 0.011023 10791800.0 27463.0 24515.0 32955.0 30835.0 37280.0 36382.0 35720.0 28606.0 22590.2 23833.0 True False 32111.943481025217 26948.687186009232 33740.77218253349 29107.414918418806 29975.251616719223 34474.063873149425 32336.343009595006 27855.122810562367 22920.538938540372 28153.734238075816 1.1405926904572474 0.9571976121577205 1.1984474918038268 1.0338740386010041 1.064698961894012 1.2244934750618566 1.1485631971996995 0.989393541013483 0.8141207395338008 1.0 14.781038669863996 -7.959265531781544 4.811828219244656 0.9039796013781342 1.1061136869253205 0.4872791967447553 0.08496455264537972 0.1537453456090372 8.16356966824716 0.05022030548063743 0.022204690300505987 1.0983341021718725e-08 7.959265531781544 0.20213408554718637 LQQTVPADAS(ph)PDSKCPICLDR ddPTM_PC-9_Lapatinib_30min_R1 2 LQQTVPADASPDSKCPICLDR 21 1 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 LQQT(0.033)VPADAS(0.967)PDSKCPICLDR;LQQT(0.125)VPADAS(0.87)PDS(0.005)KCPICLDR 73.058 0.00090062 24456000.0 45065.0 72148.0 76770.0 76074.0 65954.0 77587.0 64532.0 63969.0 71532.0 60980.0 True False 44422.36483609113 71980.94573875984 70458.26694076971 81668.73573542453 62074.71539055305 74268.78487413081 67873.151202499 66941.23327031583 63475.31289464631 71520.31174925764 0.6211153691811504 1.0064406037702567 0.9851504449223971 1.1418956900208455 0.8679312753582532 1.0384292665628894 0.9490052481937552 0.9359751325610051 0.8875144884320945 1.0 16.126065404635106 -4.758859585654265 24.996204835867555 0.9798566880810436 0.6211148941922191 0.678120039802139 0.0739997746997412 40.65216014808467 393807.9616195874 0.018202674926723745 0.12073750048776177 1.7423701184348474e-05 4.758859585654265 -0.35874179388882455 LQQTVPADASPDS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 LQQTVPADASPDSK 14 0 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 LQQTVPADAS(0.062)PDS(0.938)K 199.33 6.2954e-08 7832000.0 53056.0 51514.0 54305.0 44745.0 46596.0 53917.0 56727.0 67245.0 61005.0 46180.0 True False 69926.7043666439 68164.89308882496 53584.880217743346 34429.73155335872 40126.949705506435 50545.56146664011 61775.59310523959 56853.83038637463 64229.599755824085 44563.252256098036 1.5691562178807343 1.5296211483195163 1.2024454568486032 0.7726036545873366 0.9004493091056984 1.1342431018311383 1.3862451678846266 1.2758007440669852 1.4413131112313489 1.0 15.443566904923243 -5.284166652202463 4.422243444507673 1.1330756139529161 1.5574574363332854 0.41623376816187807 0.19566595409944812 0.20645831751481195 10.218527283511456 0.05852539895175643 0.14133772499484076 5.197964962933242e-06 5.284166652202463 0.42438182238036926 LQQTVPADASPDS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 3 LQQTVPADASPDSK 14 0 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 LQQTVPADAS(0.366)PDS(0.634)K;LQQTVPADAS(0.137)PDS(0.863)K;LQQTVPADAS(0.108)PDS(0.892)K 179.66 4.2483999999999995e-05 30828800.0 162607.0 210076.0 169406.0 180154.0 212929.0 198736.0 207110.0 202720.0 183161.0 169563.0 True False 160288.19436152832 209589.58192903057 155478.092606071 193403.1261361265 200404.93485452072 190236.52455624347 217833.14240298723 212139.11126574466 162531.47940916376 198871.73862150434 0.8059877963182652 1.053893244871382 0.7818008415060886 0.9725018118547966 1.007709472666372 0.9565789783650681 1.0953448886851165 1.0667132129291181 0.8172678558339358 1.0 17.60147874584461 -5.979701067639701 24.966797298010206 0.9968041825403208 0.8944367589505534 0.2006227917123461 0.09721855859314109 390.7672453107333 480622.9603545627 0.026462440182036306 0.039245297376531235 1.0478495527491127e-06 5.979701067639701 -0.10236742358976736 LQS(ph)IGTENTEENRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQSIGTENTEENRR 14 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 LQS(0.999)IGT(0.001)ENTEENRR 72.187 0.010711 15837000.0 12287.0 11544.0 9362.1 12592.0 21159.0 8264.9 12943.0 10930.0 8622.5 8203.8 True False 14366.946420688086 12690.012028361838 9585.327969961967 11886.511063814814 17013.045841152412 7831.474094475087 11716.945340794742 10643.099081292272 8748.587750332634 9691.083998754937 1.4824911663683733 1.3094522790218504 0.9890872859211047 1.2265409179553015 1.755535897051162 0.8081112593267417 1.209043832691996 1.0982361810773331 0.9027460448652194 1.0 13.242442332362375 -6.793384422204993 24.99999613845319 1.022605884930915 1.3230233571505985 0.4068721584399455 0.20853506695795254 242.74667076378108 189970.38758269677 0.07577727910148932 0.06683466233540937 1.6092205790923286e-07 6.793384422204993 0.3004174722196835 LQS(ph)IGTENTEENRR ddPTM_PC-9_Lapatinib_30min_R1 2 LQSIGTENTEENRR 14 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 LQS(0.898)IGT(0.084)ENT(0.018)EENRR;LQS(0.889)IGT(0.089)ENT(0.021)EENRR 74.428 0.0085583 28131000.0 28113.0 31972.0 30192.1 22527.4 29684.0 25350.5 30969.6 36686.0 34069.6 26915.4 True False 27712.103464707205 31897.970798353825 27709.82208287632 24184.140145203415 27938.045480989425 24266.31820990179 32573.054352583415 38390.56548882748 30232.322879207066 31567.69102748387 0.8778628579638637 1.0104625888089946 0.8777905884453582 0.7661041830442368 0.885020239733899 0.7687074163509373 1.0318478574889827 1.2161347326734602 0.9576982634835665 1.0 14.946161120244016 -7.415309889884056 6.1610582755770675 1.0761445815032664 0.8688009469965169 0.5078103223000103 0.08981431578898595 0.18599966694552253 9.102128413168176 0.03855618325729488 0.02567682418860013 3.8431745529906834e-08 7.415309889884056 -0.20734363450674953 LQS(ph)PIKEENTTAVEEIGR ddPTM_PC-9_AZD4547_30min_R2 2 LQSPIKEENTTAVEEIGR 18 1 S4R3Y0;S4R3P6;S4R3N2;A0A087X1L0;S4R2X9;Q9NS73-3;Q9NS73-2;Q9NS73-5;Q9NS73 S4R3Y0 MBIP MAP3K12-binding inhibitory protein 1 1 LQS(0.994)PIKEENT(0.003)T(0.003)AVEEIGR;LQS(0.821)PIKEENT(0.116)T(0.063)AVEEIGR 74.993 0.0028487 19533500.0 32697.0 34995.0 39377.0 46219.0 41063.0 39951.0 35532.0 35779.0 34167.0 40885.0 True False 43093.9658601507 46306.44938547644 38854.83525152528 35563.9236264317 35362.111248974405 37452.857654426974 38694.279165395186 30250.17766962748 35972.997866687016 39453.62859442549 1.0922687569031246 1.1736930425714809 0.9848228575106316 0.9014107166674302 0.8962955375407679 0.9492880373421163 0.9807533690541813 0.7667273897818769 0.9117791987267233 1.0 15.26787037216951 -5.445274006895908 3.479498363549629 0.909705381847657 1.131960638764714 0.6508460294371863 0.06274781393706987 0.1391217137863797 3.200423925066182 0.017210031354226128 0.03844777292624845 3.5869555353488703e-06 5.445274006895908 0.22225525691705705 LQS(ph)PIKEENTTAVEEIGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQSPIKEENTTAVEEIGR 18 1 S4R3Y0;S4R3P6;S4R3N2;A0A087X1L0;S4R2X9;Q9NS73-3;Q9NS73-2;Q9NS73-5;Q9NS73 S4R3Y0 MBIP MAP3K12-binding inhibitory protein 1 1 LQS(0.999)PIKEENT(0.001)TAVEEIGR 52.644 0.025325999999999998 6145300.0 20077.0 19479.0 17435.0 25737.0 21202.0 20242.0 22190.0 18746.0 16650.0 17845.0 True False 23475.639561174776 21412.74638777375 17850.716522605715 24295.039330479816 17047.620299830483 19180.47388599555 20088.002558312237 18253.937363028814 16893.474751294678 21080.157239057724 1.1136368336797153 1.015777356162211 0.846801867755121 1.1525075005354086 0.8087046081536964 0.9098828660754767 0.9529341897456437 0.865929848436214 0.8013922552718972 1.0 14.363598007775183 -1.5228787728810305 0.4722159489594017 0.8940714699457658 6.503933021560255 0.28781052349191616 0.09837728223900225 122.33217970557855 1.3982249433428413 0.0567059605888899 670.6588050153041 0.02999999809341174 1.5228787728810305 5.609861551614489 LQS(ph)PIKEENTTAVEEIGR ddPTM_PC-9_Lapatinib_30min_R1 2 LQSPIKEENTTAVEEIGR 18 1 S4R3Y0;S4R3P6;S4R3N2;A0A087X1L0;S4R2X9;Q9NS73-3;Q9NS73-2;Q9NS73-5;Q9NS73 S4R3Y0 MBIP MAP3K12-binding inhibitory protein 1 1 LQS(0.558)PIKEENT(0.256)T(0.187)AVEEIGR;LQS(0.984)PIKEENT(0.008)T(0.008)AVEEIGR 79.695 0.0018457 16230700.0 37695.0 40179.0 38572.0 33419.0 37890.0 41400.0 36348.0 37709.0 39750.0 33896.0 True False 37157.46238758363 40085.96799409041 35400.759052225774 35876.744742515904 35661.38469460615 39629.41850811362 38229.921587870085 39461.09780347256 35272.93641394324 39754.87843641903 0.9346642185564846 1.0083282749361415 0.890475847104981 0.9024488604560691 0.8970316624572326 0.996844162698018 0.9616410134170617 0.9926101991880992 0.8872605778522534 1.0 15.278844288101883 -6.762097780596288 24.999999994487055 0.9668324388089362 0.9277833120056368 0.1850188460072929 0.04305589852486108 35.0525311307421 1330928.6622364824 0.015084157742539225 0.014096084616257977 1.7294269381137714e-07 6.762097780596288 -0.03904912680329942 LQS(ph)PLPGESAAK ddPTM_PC-9_AZD4547_30min_R2 2 LQSPLPGESAAK 12 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 LQS(0.916)PLPGES(0.084)AAK;LQS(0.977)PLPGES(0.023)AAK 118.52 0.00058087 25583000.0 87421.0 74153.0 121392.0 173656.0 142586.0 146733.0 128888.0 132192.0 119762.0 133777.0 True False 115219.05953023936 98121.50710905077 119782.26276387625 133622.29215845474 122790.3951135151 137557.7623140104 140358.7823108596 111764.76386996295 126092.37482103122 129093.50794855005 0.892524042155239 0.7600808798855857 0.9278720879721948 1.0350814249443872 0.9511740525515269 1.0655668476282616 1.0872644530412738 0.865765952494734 0.9767522536554284 1.0 16.978056924454997 -5.490854851464245 5.113930918191617 0.9958784943396414 0.8278897913267292 0.5188142990635485 0.0655240665693963 0.14930658187459644 10.228538187354225 0.017955067774619696 0.0365086933745467 3.2295733191963616e-06 5.490854851464245 -0.16798870301291213 LQS(ph)PLPGESAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LQSPLPGESAAK 12 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 LQS(0.995)PLPGES(0.005)AAK;LQS(0.945)PLPGES(0.055)AAK 114.7 0.00075647 15111800.0 67396.0 75567.0 88323.0 104041.0 118356.0 98581.0 113424.0 97350.0 89519.0 74799.0 True False 78804.81166832389 83068.792355095 90428.95528684261 98211.92007547306 95164.99142565504 93411.23881806771 102679.65760135214 94794.66565085104 90828.04602169078 88359.4665914419 0.8918660864342132 0.9401232891003065 1.0234212447769706 1.1115042209295707 1.0770208908761372 1.0571729597461728 1.162067422567456 1.072829763551701 1.027937916846682 1.0 16.431097089005377 -5.283831512272356 2.1754723127178535 1.0789257889463764 0.8974662024107994 0.6821035473350119 0.042405311423333966 0.18274296603541884 1.6028006369513972 0.011741368598188731 0.041696497186563604 5.201977719295459e-06 5.283831512272356 -0.18145958653557692 LQS(ph)PLPGESAAK ddPTM_PC-9_Lapatinib_30min_R1 2 LQSPLPGESAAK 12 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 LQS(0.974)PLPGES(0.026)AAK;LQS(0.981)PLPGES(0.019)AAK 73.38600000000001 0.022781 21514000.0 108405.0 101942.0 125510.0 108313.0 109790.0 109516.0 92672.0 103642.0 118670.0 88095.0 True False 106859.12482095776 101705.95956229791 115191.0522826106 116278.69934157578 103332.36805544505 104832.25597426495 97470.1027124214 108457.58568372257 105304.1349495006 103322.10337079118 1.0342329601776814 0.9843581987225576 1.1148732800108165 1.1254000407278524 1.000099346454621 1.0146159684540519 0.9433615802674017 1.0497036175744674 1.0191830355175457 1.0 16.65678939284394 -6.368308903450528 23.781441505447017 1.0044275450918352 1.0626033817070368 0.3055500837206657 0.04443163086527211 28.694013572876155 6365.521015346293 0.014822031252374825 0.0168066044228776 4.282438122928885e-07 6.368308903450528 0.05817583661520165 LQS(ph)SQEPEAPPPR ddPTM_PC-9_AZD4547_30min_R2 1 LQSSQEPEAPPPR 13 0 Q5H909;Q9UNF1-2;Q9UNF1;Q5H907 Q5H909 MAGED2 Melanoma-associated antigen D2 1 LQS(0.982)S(0.018)QEPEAPPPR 135.86 5.277399999999999e-05 6961300.0 17629.0 12806.0 20724.0 25612.0 21458.0 24127.0 15584.0 32296.0 19273.0 18228.0 True False 23234.65529402075 16945.289065021036 20449.18621917895 19707.54910145544 18478.92709204132 22618.334875931996 16970.945809791698 27305.395288249783 20291.731433390672 17589.843268171404 1.320913150833104 0.9633564555793013 1.1625564769062775 1.1203936727006543 1.0505452953909316 1.2858747250386013 0.9648150669142349 1.552338748671999 1.1536050164874578 1.0 14.102455007485005 LQS(ph)SQEPEAPPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQSSQEPEAPPPR 13 0 Q5H909;Q9UNF1-2;Q9UNF1;Q5H907 Q5H909 MAGED2 Melanoma-associated antigen D2 1 LQS(0.669)S(0.331)QEPEAPPPR 156.2 0.00020195 5971700.0 16052.0 13925.0 16646.0 15318.0 18741.0 16795.0 14912.0 12566.0 12437.0 16309.0 True False 18769.28655854846 15307.381972881034 17042.90377030655 14459.782121626056 15068.835583394175 15914.240634092257 13499.427406469227 12236.155814777558 12618.867596507622 19265.692598027035 0.9742336779769127 0.7945409642033132 0.8846245046000518 0.7505456680600653 0.7821590377154335 0.8260404111151449 0.7006977474483154 0.6351267026875868 0.6549916403109171 1.0 14.233746431094696 -1.522878862626075 0.49267252598200223 0.7404293041799496 7.254603436576968 0.23145715184139637 0.1033801586494504 138.6706072795428 1.5032277721938354 0.05681610361698283 931.401375039058 0.029999991894044724 1.522878862626075 6.514174132397018 LQSEVAELK ddPTM_PC-9_Lapatinib_30min_R1 1 LQSEVAELK 9 0 F5GXM3;H3BQF7;H3BMU1;H3BUI0;J3KR23;P53990-2;P53990-3;P53990;P53990-4;P53990-5 F5GXM3 IST1 IST1 homolog 0 95.50200000000001 0.024906 11328000.0 32984.0 44928.0 41293.0 43067.0 41329.0 40899.0 39652.0 42405.0 34702.0 34750.0 False True 32513.642111475227 44823.9719763681 37898.04893558955 46234.29084730041 38898.10947594031 39149.845110225586 41704.98654127393 44375.29110706339 30793.49533173985 40756.49119853554 0.797753711257742 1.0997995818143125 0.9298653495704089 1.1344031217525834 0.9544028038738034 0.9605793815644345 1.0232722522191133 1.088790761964756 0.755548243388683 1.0 15.314742232123587 -11.192297881527416 8.653683485070081 1.000023330812491 0.9830693786757968 0.0 0.11814699692797592 4.940899375528094e-05 1.8875200368046199e-06 0.10628164456984647 0.025741616488720264 6.422470505203907e-12 11.192297881527416 -0.01695395213669426 LQSFDS(ph)PER ddPTM_PC-9_AZD4547_30min_R2 2 LQSFDSPER 9 0 E9PGM9;P78332;P78332-2 E9PGM9 RBM6 RNA-binding protein 6 1 LQS(0.03)FDS(0.97)PER;LQSFDS(1)PER 127.52 0.0013595999999999999 42258700.0 48825.0 45253.9 81070.0 94537.0 76660.0 76812.0 62490.0 80697.0 65160.0 68081.0 True False 64350.33437691095 59881.33818675271 79994.95882980296 72742.95523209014 66017.08224792106 72008.93349733035 68051.48894082932 68227.13288258282 68604.22457322339 65697.50491224349 0.9794943424848167 0.9114705081530903 1.217625523779899 1.1072407594361116 1.0048643755360946 1.096068010398834 1.0358306458020012 1.038504171105407 1.0442439886394863 1.0 16.003550959852205 -5.2019548992351154 24.999997549271765 1.0684163913927898 0.9454822646696254 0.38675199071269384 0.06173292718641676 261.08223125931687 109725.73695936275 0.015833582257798472 0.04189168950917028 6.281235850236557e-06 5.2019548992351154 -0.1229341267231644 LQSFDS(ph)PER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LQSFDSPER 9 0 E9PGM9;P78332;P78332-2 E9PGM9 RBM6 RNA-binding protein 6 1 LQS(0.006)FDS(0.994)PER;LQSFDS(1)PER;LQS(0.018)FDS(0.982)PER 105.25 0.0026486 37872800.0 101986.0 111921.0 110561.0 120414.0 125768.0 102861.0 115227.0 117227.0 102545.0 80700.0 True False 119250.2154846823 123031.7772198793 113197.19354492765 113667.59396745512 101124.6632331422 97466.78808355832 104311.86438876264 114149.91546227329 104044.52662891953 95330.27117915159 1.250916566266539 1.2905845719107314 1.1874212896363132 1.1923557182989934 1.0607822885880747 1.0224117363559329 1.0942155424349123 1.1974151971911886 1.0914112101222442 1.0 16.540646779891304 -5.853043637520453 1.7025718621962667 1.0867608551099062 1.2642684974521565 0.6555186947840586 0.054873135353622 0.24649257108613043 1.4569618786866452 0.0187769104797305 0.036151461685435905 1.4026727581789203e-06 5.853043637520453 0.17750764234225036 LQSFDS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 5 LQSFDSPER 9 0 E9PGM9;P78332;P78332-2 E9PGM9 RBM6 RNA-binding protein 6 1 LQSFDS(1)PER;LQS(0.002)FDS(0.998)PER;LQS(0.001)FDS(0.999)PER;LQSFDS(1)PER;LQSFDS(1)PER 137.4 0.0009472999999999999 87488400.0 139064.0 154558.0 160334.0 149450.0 151580.0 152457.0 130255.0 137529.0 156608.0 127104.0 True False 137080.92185878588 154200.13044701493 147151.9574271378 160441.05155058493 142664.362417746 145936.7695046251 136998.9665573903 143919.09941429843 138969.15788464958 149073.75704456583 0.9195509966103914 1.0343881680054294 0.9871083975105456 1.0762528209617794 0.9570052116892462 0.9789568090176801 0.9190012331710016 0.9654220988827268 0.9322174515471864 1.0 17.185666782266367 -6.456024414963578 24.99981351429768 0.955953625200761 1.0066660361971413 0.21376398935907803 0.042508981889903694 260.21240472524124 97304.33326312076 0.012638668919723216 0.014330898888359743 3.4992549452799293e-07 6.456024414963578 0.05071241099638035 LQSIGTENT(ph)EENRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQSIGTENTEENRR 14 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 LQS(0.051)IGT(0.101)ENT(0.848)EENRR 127.32 9.938799999999999e-05 4118500.0 14242.0 11979.0 14849.0 16754.0 18272.0 18596.0 17950.0 15306.0 13557.0 12440.0 True False 16652.889307678 13168.195953547 15203.056475146088 15815.327697200875 14691.732766649508 17620.793023612947 16249.646053253942 14904.233718047533 13755.245477675799 14695.273525014185 1.1332139738216902 0.8960837599335728 1.0345541679960948 1.0762186678784946 0.9997590546131278 1.1990789415126546 1.1057736370537041 1.014219551114694 0.9360319462078553 1.0 13.843064591856763 -7.9992644835542155 8.235403288290522 0.9701427932359645 1.059339199049282 0.19671828716229067 0.07765211744375904 0.19097832291739442 129.87249437094124 0.04734538047508365 0.021059166871850866 1.0016950241358584e-08 7.9992644835542155 0.08919640581331745 LQSIGTENTEENR ddPTM_PC-9_AZD4547_30min_R2 2 LQSIGTENTEENR 13 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ; 265.53 9.437899999999998e-55 20064200.0 26013.0 21725.8 30621.0 31569.0 27114.0 30888.0 28924.0 32369.0 31545.0 26441.0 False True 34284.59289598741 28748.23997882509 30214.945532594033 24291.254786187994 23349.689121707917 28956.568477132976 31498.179966787426 27367.114815622903 33212.40429960611 25515.308638014034 1.3436871715871952 1.1267055549543488 1.1841889103225753 0.9520266884013944 0.9151246983906883 1.1348703983142094 1.23448163663832 1.07257627974956 1.3016657870296948 1.0 14.639075472490372 -4.452989671769308 1.6875313181040736 1.0959689660565302 1.6695679308238127 0.2837970455486306 0.11571013956131761 3.693992657416365 5.0746905343633575 0.03335864314095464 4.506515588325013 3.523792510958201e-05 4.452989671769308 0.5735989647672826 LQSIGTENTEENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LQSIGTENTEENR 13 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ;;; 238.07 1.9817000000000002e-25 15852400.0 35580.2 43851.0 33688.5 35124.5 39705.8 32638.4 30401.6 36844.7 32047.800000000003 28778.100000000002 False True 41603.225119017334 48204.23747883709 34491.761604347725 33156.58814016543 31925.733520470232 30926.784847380583 27521.740359476586 35877.56566518658 32516.438446519023 33995.34172268576 1.2237919376834705 1.417965963456383 1.0146025854280705 0.9753273966367985 0.9391208295801764 0.9097359602872453 0.809573869972626 1.0553671134667482 0.9564968845369826 1.0 15.053049451382948 -5.375447962957397 4.622572789937808 0.9472161030564422 1.3186614685954905 0.7922881178262098 0.07482631989490476 0.08808649016098802 2.93644637349119 0.019919956018736442 0.0435374841539126 4.2126175919564544e-06 5.375447962957397 0.3714453655390483 LQSIGTENTEENR ddPTM_PC-9_Lapatinib_30min_R1 4 LQSIGTENTEENR 13 0 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ;;; 274.59 6.0577e-68 52290600.0 46613.4 55944.1 52560.0 49875.0 60679.2 58843.3 55569.0 54212.0 57489.3 50931.9 False True 45948.684368149356 55814.56487364526 48238.71968746724 53542.97387812263 57110.168755897204 56326.709229431945 58446.09091879477 56730.88743063608 51014.249644832875 59735.41105250918 0.7692034516638566 0.9343631171229845 0.8075397630571921 0.8963355727318388 0.9560521598436091 0.9429366641491612 0.9784161503035266 0.9497028049370576 0.8540034921663107 1.0 15.86629879185371 -6.017199824139553 4.257768347566636 0.9449871724266048 0.8466197278103956 0.46150046836932257 0.052808536312328805 0.19686144131797698 8.491458555898536 0.014986966657667754 0.02111516219095962 9.61169930725895e-07 6.017199824139553 -0.09836744461620917 LQSIGTENTEENRR ddPTM_PC-9_AZD4547_30min_R2 3 LQSIGTENTEENRR 14 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ;; 120.92 5.0416000000000007e-05 242017000.0 77367.0 84814.0 121396.0 171999.0 124725.0 88015.0 90884.0 140345.0 82805.0 92940.0 False True 101968.09666643034 112228.46687183308 119786.20972126265 132347.28790806004 107409.08666021291 82511.4081363269 98972.49993436277 118657.9050572647 87181.90325024199 89686.1988887342 1.1369430071725217 1.2513460071048956 1.3356147456965022 1.4756706109515434 1.1976099778012215 0.9200011725180992 1.10354214093909 1.3230341627531026 0.972077134837668 1.0 16.45259837665985 -6.524171820436271 24.98566736293888 1.083341719049915 1.303685286258886 0.4264987929683486 0.12845510447446962 46.25977140817231 893833.9144031475 0.04370155827136146 0.04403305863983804 2.9910810375831867e-07 6.524171820436271 0.22034356720897086 LQSIGTENTEENRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LQSIGTENTEENRR 14 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ;;;;; 148.41 9.0134e-05 293170000.0 160079.0 144576.0 177210.0 196250.0 209199.0 175491.0 203755.0 158818.0 164512.0 132094.0 False True 187177.21299563168 158928.5498105029 181435.35847266729 185254.74875108458 168207.9576975872 166287.94302575078 184453.85134154648 154649.1957815805 166917.6767738736 156041.59654447105 1.1995340802751089 1.01850117744219 1.162737132216916 1.1872138766427447 1.077968704643757 1.065664199214724 1.1820812874660513 0.9910767334241307 1.069699877918789 1.0 17.25157113896683 -7.771264528996375 24.99675457250969 1.0227912154094732 1.1228148663434467 0.4070610586957426 0.059180891286131944 222.1091890083674 565071.9300243693 0.03107214055735076 0.015212581411944186 1.6933060926444995e-08 7.771264528996375 0.10002365093397358 LQSIGTENTEENRR ddPTM_PC-9_Lapatinib_30min_R1 4 LQSIGTENTEENRR 14 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ;;; 138.55 5.6132e-05 343304000.0 250071.0 151780.0 170476.0 159768.0 149584.0 151305.0 140268.0 132449.0 177679.0 142883.0 False True 246504.941682595 151428.56273533546 156460.12133639012 171517.87169042404 140785.7632134593 144834.0378591821 147530.39070340508 138603.06406884655 157666.91997718296 167580.13617036978 1.4709675461296117 0.9036188070726123 0.9336435982921357 1.023497626926684 0.8401100896011322 0.8642673360280426 0.8803572671251372 0.8270852813243702 0.9408449210047868 1.0 17.354491626177747 -4.761259536774361 24.989942753037393 0.90653858706262 1.4709681702848827 0.8818974215832416 0.061263758308630296 1.340010194072107 185695.91468856556 0.015573212211556959 0.08757595827604206 1.7327681764728394e-05 4.761259536774361 0.5644295832222627 LQSS(ph)LESEVSVLASK ddPTM_PC-9_AZD4547_30min_R2 1 LQSSLESEVSVLASK 15 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 LQS(0.088)S(0.898)LES(0.014)EVSVLASK 135.69 3.5514e-06 0.0 6497.3 4164.7 9187.8 12032.0 8838.9 7896.9 7901.4 9341.0 8013.5 6444.9 True False 8563.306247764538 5510.857829852657 9065.96376879812 9258.208292546926 7611.7713055198055 7403.105594634537 8604.60929295997 7897.563084826028 8437.077250115513 6219.266012674889 1.3768998190964152 0.8860945678511752 1.4577224627989298 1.4886335901501335 1.2239018704147702 1.190350369247268 1.3835409637445548 1.269854524429533 1.3566033729576314 1.0 12.602528610619649 -10.643821805358803 5.321041205421879 0.9999939429153495 1.2882618520797264 0.22406873154636886 0.16318005813230826 1.1766772161811386e-05 1.943837181107556e-06 0.1585446216064501 0.038451911198422256 2.270796387423301e-11 10.643821805358803 0.28826790916437695 LQSS(ph)LESEVSVLASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LQSSLESEVSVLASK 15 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 LQS(0.206)S(0.794)LESEVSVLASK;LQS(0.023)S(0.977)LESEVSVLASK 144.5 0.00010628 1474600.0 12621.9 13746.6 14330.599999999999 15618.199999999999 17004.8 16798.1 14429.3 14015.0 12758.3 12442.8 True False 14758.538376111563 15111.27159988555 14672.295853103147 14743.162888887586 13672.83150997819 15917.178064635005 13062.452244914592 13647.12110011996 12944.866001167746 14698.5811428494 1.0040791170711965 1.0280768907573719 0.9982117124441606 1.0030330645934402 0.9302143776394214 1.0829057519186762 0.8886879704895356 0.9284652013340107 0.8806881341377085 1.0 13.8433892776744 -7.28367910697714 24.99927202122709 0.9184990899861684 1.0045044981156175 0.4354176729378795 0.0461773547423889 732.058344571898 822889.7001768633 0.018225043711827194 0.012299136832745533 5.203803549712451e-08 7.28367910697714 0.08600540812944912 LQSS(ph)LESEVSVLASK ddPTM_PC-9_Lapatinib_30min_R1 2 LQSSLESEVSVLASK 15 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 LQS(0.097)S(0.899)LES(0.004)EVSVLASK;LQS(0.024)S(0.971)LES(0.005)EVSVLASK 155.2 0.00018864 3093900.0 28219.6 23291.0 28011.0 24638.0 24998.1 23383.7 18123.6 19196.1 25381.4 19553.8 True False 27817.183329159172 23237.07112049478 25708.043705586846 26449.960709958632 23527.760906155563 22383.633661067062 19061.951328544128 20088.02088480839 22522.679454009034 22933.648276199277 1.2129419180997933 1.0132304655866897 1.120974883541179 1.1533254714387773 1.0259057182181024 0.9760171339287947 0.8311783236131154 0.875919114258672 0.9820800939632117 1.0 14.485178256112832 -6.670505382646412 2.24867212365436 0.9129955132227489 1.1157663810399638 0.64625460690635 0.06661822806694752 0.18460880978857191 1.9101355810003584 0.02477745024954249 0.024227194506848137 2.1354756187956364e-07 6.670505382646412 0.20277086781721498 LQSS(ph)QEPEAPPPR ddPTM_PC-9_AZD4547_30min_R2 1 LQSSQEPEAPPPR 13 0 Q5H909;Q9UNF1-2;Q9UNF1;Q5H907 Q5H909 MAGED2 Melanoma-associated antigen D2 1 LQS(0.141)S(0.859)QEPEAPPPR 88.22399999999999 0.006708700000000001 7781500.0 30062.0 30252.0 35837.0 49443.0 49130.0 43306.0 34644.0 54183.0 36611.0 40930.0 True False 39621.090671555525 40030.36738989663 35361.77796452019 38044.68023673517 42309.14754553035 40598.06897405857 37727.24888567915 45810.26235147504 38546.18271716213 39497.05315812241 1.003140424500444 1.0135026334658221 0.8953016778986758 0.9632283219820776 1.0711975745671458 1.0278758977670652 0.9551914856696263 1.1598400054828986 0.9759255345670076 1.0 15.269457398592213 -6.243100296091937 23.85005036910668 1.0356499434238875 0.9667373776794399 0.20356824227825965 0.06056919492310496 694.2734781378082 902904.1691208299 0.01767069194462196 0.02276054807146543 5.713466744702494e-07 6.243100296091937 -0.0689125657444476 LQSS(ph)QEPEAPPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQSSQEPEAPPPR 13 0 Q5H909;Q9UNF1-2;Q9UNF1;Q5H907 Q5H909 MAGED2 Melanoma-associated antigen D2 1 LQS(0.149)S(0.851)QEPEAPPPR 74.649 0.019246 5181300.0 9120.1 12699.0 11009.0 10172.0 13889.0 11833.0 11148.0 9260.0 11688.0 11174.0 True False 10663.952799814218 13959.672795232762 11271.496311864994 9602.095818068958 11167.550153020731 11212.456649194028 10091.980735469355 9016.934811781011 11858.914888476405 13199.757746664678 0.8078900389296002 1.057570378423051 0.8539169072790811 0.7274448518189829 0.8460420537522785 0.8494441234747052 0.7645580266819216 0.6831136589654015 0.8984191313263247 1.0 13.688223831792827 -5.51158391519854 24.24830918739451 0.8089071157217279 0.938483586862642 0.13910595627801914 0.10159449717754247 503.0012738172749 1079865.297380898 0.025495609652063253 0.048519427452117986 3.079045345074782e-06 5.51158391519854 0.12957647114091408 LQSS(ph)QEPEAPPPR ddPTM_PC-9_Lapatinib_30min_R1 2 LQSSQEPEAPPPR 13 0 Q5H909;Q9UNF1-2;Q9UNF1;Q5H907 Q5H909 MAGED2 Melanoma-associated antigen D2 1 LQS(0.17)S(0.83)QEPEAPPPR;LQS(0.065)S(0.935)QEPEAPPPR 157.23 0.00022282 12843300.0 34400.0 36857.0 41848.0 32839.0 40456.0 39787.0 40699.0 36613.0 41316.0 30711.0 True False 33909.449691812624 36771.659880987354 38407.41897795147 35254.08960769264 38076.45761955624 38085.40275802696 42806.19507826358 38314.173642327856 36662.55700323221 36019.355430164745 0.941423001240462 1.0208861164181906 1.0662994525933915 0.9787540389512015 1.0571110216944293 1.0573593642414818 1.1884220183022802 1.063710696228653 1.0178571094731141 1.0 15.1364847438579 -6.465473621634245 3.6425922342907597 1.076155094578339 1.0078322999022697 0.21456746206489263 0.05590700170225385 0.3648506647140137 9.65956813215077 0.018864590123334298 0.02082994689189405 3.423941834806425e-07 6.465473621634245 -0.06832279467606917 LQSSSYLDDSS(ph)PTGLMK ddPTM_PC-9_AZD4547_30min_R2 1 LQSSSYLDDSSPTGLMK 17 0 Q8WYA1-6;Q8WYA1-8;Q8WYA1-7;Q8WYA1-4;Q8WYA1-3;H0Y5R1;Q8WYA1-9;Q8WYA1-5;Q8WYA1-2;Q8WYA1 Q8WYA1-6 ARNTL2 Aryl hydrocarbon receptor nuclear translocator-like protein 2 1 LQSS(0.001)S(0.002)Y(0.005)LDDS(0.162)S(0.803)PT(0.027)GLMK 57.595 0.039643 5861200.0 35485.0 34588.0 40136.0 56366.0 61404.0 57184.0 40524.0 48521.0 43828.0 48591.0 True False 46768.49186614817 45767.89459479524 39603.77041560346 43371.68954601897 52879.114510192216 53608.27544018302 44130.55749460979 41023.19435165865 46144.65860336466 46889.84387994935 0.9974119765868303 0.9760726589743697 0.8446129724167944 0.9249698006472828 1.1277306583825917 1.1432811671848313 0.941153858554017 0.8748844303403758 0.9841077466904653 1.0 15.516987855153335 -4.756184300422545 19.732913582614856 0.9783460259203571 0.9974123417923051 0.0032347394289131692 0.09102073439220154 167.01550751110676 625939.0573497263 0.02532080219859259 0.19054853044828046 1.7531363700273012e-05 4.756184300422545 0.01906631587194796 LQSSSYLDDSS(ph)PTGLMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LQSSSYLDDSSPTGLMK 17 0 Q8WYA1-6;Q8WYA1-8;Q8WYA1-7;Q8WYA1-4;Q8WYA1-3;H0Y5R1;Q8WYA1-9;Q8WYA1-5;Q8WYA1-2;Q8WYA1 Q8WYA1-6 ARNTL2 Aryl hydrocarbon receptor nuclear translocator-like protein 2 1 LQSSSYLDDS(0.195)S(0.609)PT(0.195)GLMK;LQSSSYLDDS(0.198)S(0.604)PT(0.198)GLMK 103.39 0.00076591 10686800.0 91827.0 86140.0 98833.0 94650.0 108728.0 99887.0 109932.0 111817.0 90783.0 76184.0 True False 107371.49743407873 94691.40992057232 101189.55354623962 89347.06735944032 87423.52891047878 94648.74987898616 99518.44512124319 108881.92222990477 92110.52963043745 89995.55612778763 1.1930755478817026 1.0521787296487939 1.124383890717418 0.9927942134450894 0.9714205086564859 1.0517047057811533 1.1058151024694343 1.2098588743126357 1.0235008659721676 1.0 16.45756614420634 -4.039621843406739 1.8559983131090982 1.0628253016740776 2.227290481312651 0.24854593426130045 0.06841114813560807 21.08133765867501 9.181372525254117 0.019709353958948746 82.9688106543804 9.128053074444502e-05 4.039621843406739 1.1644651796385734 LQST(ph)PGAANK ddPTM_PC-9_AZD4547_30min_R2 1 LQSTPGAANK 10 0 Q8IZD4;Q8IZD4-2;F5GZK9 Q8IZD4 DCP1B mRNA-decapping enzyme 1B 1 LQS(0.071)T(0.929)PGAANK 80.834 0.028946 0.0 24811.0 28316.0 33692.0 36043.0 37567.0 34350.0 27475.0 37703.0 30069.0 33788.0 True False 32700.381899140553 37468.593250440055 33245.22206603827 27733.843208798942 32351.470503621786 32202.089069849728 29920.22177387236 31876.86767874912 31658.385952919834 32605.092404266805 1.0029225341149863 1.1491638418278733 1.0196328123789553 0.8505985158677116 0.9922214021815859 0.9876398652879039 0.9176548682302432 0.9776653071094383 0.9709644604097769 1.0 14.992809687951373 -5.52455236578412 24.999977181265642 0.9552171489049914 1.0781319862199434 0.45247780461898424 0.05313748035234415 39.971820186625315 597082.2235145342 0.01366042774424884 0.02388089929289245 2.9884612865122786e-06 5.52455236578412 0.12291483731495201 LQSVQATGPSS(ph)PGR ddPTM_PC-9_AZD4547_30min_R2 1 LQSVQATGPSSPGR 14 0 A0A096LNU0;D6REY2;P23508;P23508-2 A0A096LNU0 MCC Colorectal mutant cancer protein 1 LQSVQATGPS(0.066)S(0.934)PGR 106.6 0.00086021 4580900.0 27948.0 17637.0 28677.0 40282.0 34616.0 29286.0 27467.0 30272.0 20258.0 23064.0 True False 36834.8826454871 23337.815339667024 28296.72424278105 30995.607250696095 29810.165915653943 27454.74179038191 29911.50978937041 25594.157981356737 21328.79652247332 22256.536380135225 1.6550141502863664 1.0485825350838003 1.2713893913896195 1.3926518808362658 1.339389265540015 1.233558596965082 1.3439427087166864 1.1499614110756453 0.9583160721050044 1.0 14.441941473756671 -8.013265737405355 2.86296022109945 0.9807691853767784 1.3132557561320561 0.4854554744901133 0.14327270902225875 0.23641968851495487 3.738117647906752 0.10450695866119944 0.03711883424018688 9.699163103494326e-09 8.013265737405355 0.33248657075527777 LQSVQATGPSS(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 2 LQSVQATGPSSPGR 14 0 A0A096LNU0;D6REY2;P23508;P23508-2 A0A096LNU0 MCC Colorectal mutant cancer protein 1 LQS(0.001)VQAT(0.002)GPS(0.144)S(0.853)PGR;LQSVQATGPS(0.088)S(0.912)PGR 118.52 0.00011439 3354800.0 47332.0 34295.0 39185.0 40386.0 34024.0 36648.0 26200.0 33225.0 45533.0 24288.0 True False 46657.03700037427 34215.59203457853 35963.3605584742 43356.12116374663 32022.775213757726 35080.650470660585 27556.507802415446 34768.75479382578 40404.59405625352 28486.148438274296 1.6378850619792942 1.2011308622055092 1.2624858933246814 1.522007134720006 1.1241525081267771 1.231498549081695 0.967365169149727 1.220549519678487 1.418394422250692 1.0 14.79797295015346 -6.279001748645864 24.78193189029319 1.1652646764902082 1.3810102649092142 0.343173282636286 0.16491036199630074 968.0373536374342 1365976.0276502287 0.051069754388966764 0.05803840204343298 5.26015148435946e-07 6.279001748645864 0.21574558841900604 LQT(ph)ARPPT(ph)AHPAKASARPVGISEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQTARPPTAHPAKASARPVGISEPK 25 3 E5RJS6;E5RH60;Q8TAG6 E5RJS6 C8orf46 Uncharacterized protein C8orf46 2 LQT(0.863)ARPPT(0.876)AHPAKAS(0.259)ARPVGIS(0.002)EPK 41.49100000000001 0.046301 6535400.0 26100.0 25178.0 21827.0 31262.0 25406.0 30322.0 27887.0 39991.0 28863.0 28381.0 True False 30518.214501502294 27677.50544439488 22347.438459358465 29510.491492771507 20427.876678497007 28731.8609411697 25245.341475604037 38941.27862396697 29285.066771568683 33526.2506361276 0.9102781826911515 0.8255472926211986 0.6665653938432666 0.8802204521185334 0.6093099076364984 0.8569959478322485 0.7530022294947551 1.1615160623420318 0.8734966247615934 1.0 15.033003529811518 -7.741626255568833 24.999139720394076 1.0131297900325278 0.7824767724157758 0.47256356263770005 0.10921288022963038 185.45792968605963 234001.39943514648 0.048685565368018116 0.028060148198120867 1.812899563625547e-08 7.741626255568833 -0.23065301761675194 LQTASDESYKDPTNIQSK ddPTM_PC-9_Lapatinib_30min_R1 1 LQTASDESYKDPTNIQSK 18 1 Q13813-3;Q13813 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 92.236 0.007799899999999999 0.0 11736.0 9733.9 13196.0 11285.0 12320.0 8892.4 11046.0 10322.0 12417.0 11589.0 False True 11568.642487881181 9711.36175259904 12111.075818033069 12114.93654565642 11595.361822051935 8512.09278119685 11617.9078315069 10801.597802313609 11018.466703193295 13592.143208628158 0.8511271776872923 0.7144834779576457 0.8910350363543166 0.8913190774774928 0.8530929702602982 0.626250963556171 0.8547517233435244 0.7946942315511258 0.8106496918159957 1.0 13.73048533769108 -8.638768444118538 16.480208479194214 1.0000000001599993 0.8083294289074829 0.344946653642876 0.07865335300234631 8058.137567807313 1145920.891416719 0.0770460009765647 0.01989319192932198 2.297373228467708e-09 8.638768444118538 -0.1916705712525164 LQTPNT(ph)FPK ddPTM_PC-9_AZD4547_30min_R2 1 LQTPNTFPK 9 0 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 LQT(0.002)PNT(0.998)FPK 89.266 0.023176 11972000.0 35412.0 31957.0 35503.0 50374.0 37530.0 33316.0 44852.0 43383.0 40996.0 45672.0 True False 46672.279384642505 42286.47529680439 35032.20702275189 38761.05257054181 32319.6073149553 31232.745253307537 48843.74111016286 36679.15419216436 43162.96486500722 44073.03718147487 1.0589757904013968 0.9594636086159857 0.7948670947841304 0.8794731438847642 0.7333192668768499 0.7086587911948018 1.1082454088436013 0.8322356828083913 0.9793508145871512 1.0 15.427608699256943 -7.262154092267404 24.99948454398598 0.9659776075175983 0.8532452862715727 0.21454686800302547 0.11508875061966638 124.34219839177182 4349159.959660052 0.048759126118187286 0.035092691451217975 5.468219102830065e-08 7.262154092267404 -0.11273232124602561 LQTPNT(ph)FPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQTPNTFPK 9 0 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 LQT(0.37)PNT(0.63)FPK 79.23 0.028942000000000002 0.0 32870.0 33282.0 24588.0 34166.0 50671.0 34155.0 34539.0 28772.0 29204.0 27784.0 True False 38434.24178790731 36586.017006924696 25174.27117050926 32251.78978766651 40742.381294817045 32363.851673558835 31267.21587929458 28016.765486453907 29631.05325146005 32821.01926197703 1.171025234808389 1.1147130049464793 0.7670167391685337 0.982656557074997 1.241350275249278 0.9860708899754426 0.9526582836967978 0.8536226514729595 0.9028072228636561 1.0 15.00233242222089 -7.234645040132945 3.296555345624086 0.9114366586908391 1.0431615094151916 0.18058170904616644 0.1242721322513505 0.469229559831591 10.57414524334222 0.05725710468354361 0.04043729397964049 5.825791799385529e-08 7.234645040132945 0.13172485072435247 LQTPNT(ph)FPK ddPTM_PC-9_Lapatinib_30min_R1 2 LQTPNTFPK 9 0 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 LQT(0.44)PNT(0.56)FPK;LQT(0.007)PNT(0.993)FPK 95.094 0.0066333 7112300.0 64896.0 63777.0 62280.0 67872.0 68314.0 56165.0 55483.0 46121.0 64614.0 45055.0 True False 63970.571139531174 63629.328274947235 57159.578807752296 72863.53329435481 64295.904830491534 53762.953877009735 58355.638259595995 48263.95003298836 57336.49090441586 52842.696717986175 1.2105849079000046 1.2041271968864071 1.0816930693905478 1.3788761327457784 1.2167415522646294 1.0174150301967904 1.1043274072674905 0.913351381186431 1.0850409700022015 1.0 15.689416472977316 -6.759904225139474 24.363782623889435 1.0236301673163017 1.218931426088711 0.5823099067298074 0.0823116379847459 21.824716393344954 346373.14066435595 0.027875003885029382 0.026470944578038755 1.7381841078203906e-07 6.759904225139474 0.19530125877240923 LQTTDNLLPMS(ph)PEEFDEVSR ddPTM_PC-9_AZD4547_30min_R2 1 LQTTDNLLPMSPEEFDEVSR 20 0 A0A669KB68;A0A669KB56;A0A669KBA4;A0A669KB53;P42224 A0A669KB68 STAT1 Signal transducer and activator of transcription 1-alpha/beta 1 LQTTDNLLPMS(1)PEEFDEVSR 143.35 1.2064e-10 0.0 7721.0 8172.6 10497.0 15973.0 13332.0 10705.0 8903.0 12786.0 9193.0 11890.0 True False 10176.117393223336 10814.233126096438 10357.802921382045 12290.67163038996 11481.081927071249 10035.614657721724 9695.349752603664 10810.217493050588 9678.923212118527 11473.734719034337 0.8869054098262947 0.9425207563981918 0.9027403173440102 1.0712006100333107 1.000640350175146 0.8746598124735405 0.8450038274389922 0.9421707715724847 0.8435721627816346 1.0 13.486047446894784 -6.771109538358326 24.990824810153313 0.893962138913295 0.962693558374272 0.1712524649226892 0.06468049946172533 336.28509501871855 869064.5997388595 0.02308201875668839 0.020607604696120312 1.6939105060991413e-07 6.771109538358326 0.06873141946097694 LQVES(ph)Y(ph)IY(ph)ALLSS(ph)SAVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQVESYIYALLSSSAVLR 18 0 Q9HCE0-2;Q9HCE0 Q9HCE0-2 EPG5 Ectopic P granules protein 5 homolog 4 LQVES(0.998)Y(0.998)IY(0.996)ALLS(0.178)S(0.439)S(0.391)AVLR 42.185 0.045903 0.0 7134.8 9816.7 12904.0 12855.0 12922.0 9861.3 11340.0 10645.0 14118.0 9496.9 True False 8342.580721276581 10791.237099689848 13211.680298692518 12134.776026472311 10390.02686135315 9344.156068173497 10265.793105509732 10365.58002930981 14324.449041368074 11218.612792580965 0.743637459953485 0.9619047648053468 1.1776572151085916 1.0816645739388757 0.926141854920265 0.8329154629842405 0.9150679585178886 0.9239627234629865 1.2768467283977432 1.0 13.453606673945997 -8.237726709561668 24.841512659833697 1.138423411211805 0.9528069194205063 0.26207473652584756 0.12909680903387163 924.4842688815177 968497.5596437438 0.09209925266904664 0.03476522007689374 5.7845994298384436e-09 8.237726709561668 -0.1856164917912987 LQWDGSSDLS(ph)PSDSGSSK ddPTM_PC-9_AZD4547_30min_R2 2 LQWDGSSDLSPSDSGSSK 18 0 K7EJK2;K7ENU1;K7EKG9;Q14CW9;Q14CW9-2 K7EJK2 ATXN7L3 Ataxin-7-like protein 3 1 LQWDGSSDLS(0.304)PS(0.304)DS(0.304)GS(0.082)S(0.006)K;LQWDGS(0.001)S(0.012)DLS(0.959)PS(0.001)DS(0.024)GS(0.002)S(0.001)K 219.99 7.122299999999999e-28 13074900.0 90124.0 78082.0 103970.0 136557.0 132656.0 118850.0 99556.0 105031.0 101651.0 111378.0 True False 118781.55730434666 103320.47952326821 102591.28986720889 105075.89343461861 114239.00420923831 111418.29071183792 108416.29113447263 88800.87232227423 107024.06433537061 107478.69012082469 1.105163797314757 0.9613113018694038 0.9545267973760984 0.9776439712513717 1.0628991112639525 1.0366547134746846 1.0087235991859773 0.8262184087138265 0.9957700844237775 1.0 16.71369111839489 -7.57629447700849 24.999912640137754 0.9300904837846645 1.012348811068304 0.22521259643889147 0.06237301368402761 129.62209264087608 60664.82818641777 0.028827594323216826 0.016643620610598975 2.652806194562256e-08 7.57629447700849 0.08225832728363958 LQWDGSSDLSPS(ph)DSGSSK ddPTM_PC-9_Lapatinib_30min_R1 1 LQWDGSSDLSPSDSGSSK 18 0 K7EJK2;K7ENU1;K7EKG9;Q14CW9;Q14CW9-2 K7EJK2 ATXN7L3 Ataxin-7-like protein 3 1 LQWDGSSDLS(0.11)PS(0.399)DS(0.361)GS(0.111)S(0.018)K 183.65 1.6679e-10 5720500.0 53395.0 45893.0 55555.0 48613.0 51334.0 46161.0 42909.0 49750.0 47815.0 44468.0 True False 52633.5775085562 45786.737578157525 50987.4823485016 52188.16218821406 48314.63504652708 44186.80163654673 45130.61806465053 52061.566621304235 42429.57118572821 52154.23455011454 1.0091908732354429 0.8779102593129127 0.9776288117028769 1.0006505250895192 0.9263799088087848 0.8472332499499733 0.8653298903521424 0.9982231945380914 0.8135402916316988 1.0 15.670496773549212 -6.517659690233953 24.819601275267907 0.9005636728810935 0.961169436225701 0.16335697337654143 0.06492411263830598 386.5232281185539 1838151.1183174525 0.02034328445952657 0.020920362776399797 3.036269449317865e-07 6.517659690233953 0.06060576334460743 LQYKT(ph)PPPSYNSALAQPVTTVPSMGETER ddPTM_PC-9_AZD4547_30min_R2 1 LQYKTPPPSYNSALAQPVTTVPSMGETER 29 1 E9PR71;Q9P2Y5-2;Q9P2Y5 E9PR71 UVRAG UV radiation resistance-associated gene protein 1 LQY(0.04)KT(0.318)PPPS(0.318)Y(0.211)NS(0.109)ALAQPVT(0.001)T(0.001)VPS(0.001)MGETER 42.253 0.034559 7199900.0 22660.0 18763.0 29339.0 36436.0 32714.0 26679.0 25269.0 31960.0 26199.0 27572.0 True False 29865.40864271998 24827.772819536924 28949.94569023794 28036.243130588424 28172.225784744132 25010.757912504243 27517.89204746063 27021.31636773789 27583.825653681422 26606.712672263657 1.1224764596286776 0.933139434599104 1.0880692420306775 1.0537281879175924 1.058839028021393 0.9400168378777913 1.0342462214863108 1.0155826727105013 1.0367243031280735 1.0 14.69950265223984 LQYKT(ph)PPPSYNSALAQPVTTVPSMGETER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LQYKTPPPSYNSALAQPVTTVPSMGETER 29 1 E9PR71;Q9P2Y5-2;Q9P2Y5 E9PR71 UVRAG UV radiation resistance-associated gene protein 1 LQY(0.273)KT(0.709)PPPS(0.006)Y(0.005)NS(0.007)ALAQPVTTVPSMGETER 52.739 0.0043076 12767000.0 14581.0 13707.0 19095.0 18579.0 21515.0 27393.0 27408.0 23449.0 23029.0 24426.0 True False 17049.275312122798 15067.740373592836 19550.29721819077 17538.07886393069 17299.290196719783 25956.46285737953 24811.715823263738 22833.488596269206 23365.755558412326 28854.240443890394 0.5908759007285813 0.5222019412672942 0.6775536946192724 0.6078163415195428 0.5995406543575379 0.8995718638948114 0.8598984219152225 0.7913390976508611 0.8097858477283119 1.0 14.816495733699965 -6.75591544865222 24.999885107681788 0.8583139626868933 0.6000853756024374 0.8189638227044225 0.06390018358590646 58.21475456439652 263464.8410778004 0.02132802737938699 0.020751767374889395 1.7542219922422238e-07 6.75591544865222 -0.25822858708445595 LRAETEQGEQQR ddPTM_PC-9_Lapatinib_30min_R1 1 LRAETEQGEQQR 12 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 149.41 1.9555999999999999e-07 0.0 10123.0 7628.0 9893.5 8110.7 10232.0 8435.4 5486.0 7805.5 10042.0 6763.5 False True 9978.644163669162 7610.337834662919 9080.094620014404 8707.18793450204 9630.17387688599 8074.637605877815 5770.03823679584 8168.172025378688 8910.96421305203 7932.561963202737 1.2579346004427967 0.9593795636221262 1.1446610391617231 1.097651423952641 1.2140055030843844 1.017910435913912 0.7273864690325359 1.029701635268516 1.123340007224383 1.0 12.95357117009667 -6.989326682512606 22.95033703367157 0.9583059599419554 1.1227253258841747 0.29960946597516636 0.11908027399500082 102.68117265929354 220787.37496767833 0.042393588669624664 0.03733479577514607 1.0248807063200987e-07 6.989326682512606 0.1644193659422193 LRDLEDSLAR ddPTM_PC-9_AZD4547_30min_R2 4 LRDLEDSLAR 10 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ;;; 172.88 0.00019726 80178600.0 151994.0 125307.0 196685.0 348941.0 262657.0 185018.0 150595.0 218521.0 160042.0 199667.0 False True 200324.9303284017 165810.03723805948 194076.8283883038 268498.04353470914 226191.60933984065 173448.79521180366 163997.66325882828 184753.60056303084 168501.4933877813 192676.71910390494 1.0396945269779703 0.8605608296072499 1.0072666240680788 1.3935157541784589 1.1739436419293714 0.9002062938297584 0.85115453502397 0.9588786928814094 0.8745295963697272 1.0 17.555822737495383 -6.775692220773303 24.574339424583695 0.9102712231474643 1.0936826261041321 0.3094130835383988 0.13279964834740376 273.067999424782 470812.5865773885 0.052483704844616494 0.046511547507665035 1.6761303084175033e-07 6.775692220773303 0.1834114029566678 LRDLEDSLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LRDLEDSLAR 10 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ;;; 172.88 0.00018272 51611100.0 139488.0 82518.0 141050.0 177702.0 191624.0 193762.0 181958.0 189691.0 174549.0 134568.0 False True 163100.56338641932 90709.84169753642 144413.16693510368 167745.93305765733 154076.65278439352 183600.77962149342 164721.62097816024 184711.8122442283 177101.44891073497 158964.11316029774 1.0260212833191504 0.5706309423817285 0.9084639549398106 1.055244040448954 0.969254316092238 1.1549825678979024 1.0362189157250647 1.1619717719430602 1.1140970461185018 1.0 17.278341582026265 -5.635516528662941 3.517480398260345 1.0758800256372527 0.7864376085619736 0.46551525977791086 0.11833511430900572 0.17470645790417375 4.163065613489455 0.03130070836323177 0.05819930538894176 2.3146400922550403e-06 5.635516528662941 -0.28944241707527907 LRDLEDSLAR ddPTM_PC-9_Lapatinib_30min_R1 4 LRDLEDSLAR 10 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ;;; 182.16 0.00015628 58757000.0 301894.0 198136.0 248700.0 211502.0 208512.0 208746.0 158196.0 155669.0 234068.0 155390.0 False True 297588.936199421 197677.22826543983 228252.84600976238 227056.56262998914 196247.73411036446 199818.42019069314 166386.6148210272 162901.95003762437 207704.79699468872 182248.9544558396 1.6328704715369395 1.0846549372843652 1.2524233496498325 1.2458593428309999 1.076811302958212 1.0964036572243314 0.9129633435638943 0.8938429881478241 1.1396762061810197 1.0 17.475551012414527 -1.5228787452803376 0.4212718696263445 0.9937620957983921 10.826041924613294 0.6580511851215272 0.11797836026181045 50.92687782807834 0.6509932762938917 0.08126115075401545 422.35785685329876 0.029999999999999995 1.5228787452803376 9.832279828814903 LREDLER ddPTM_PC-9_AZD4547_30min_R2 1 LREDLER 7 1 P62269;J3JS69 P62269 RPS18 40S ribosomal protein S18 0 85.064 0.025322 4322100.0 10119.0 10227.0 12209.0 14870.0 11743.0 11154.0 11195.0 12226.0 9713.4 11475.0 False True 13336.631511724767 13532.677750114806 12047.100682781112 11441.951239209837 10112.687148934723 10456.53861674247 12191.333312411327 10336.752625530775 10226.83049370088 11073.263742718167 1.2043993371416808 1.2221038046722188 1.0879448880374898 1.0332952871942673 0.9132526221625378 0.9443050269274712 1.1009701923182682 0.9334874401712209 0.9235606349958109 1.0 13.434792885450298 -5.559391179941691 1.8179529210002667 0.9721584565412286 1.2200530389130515 0.7641613890716146 0.052717580802153156 0.17716497011725785 1.1480859544120021 0.01652640527056088 0.04360406378430395 2.75809245394822e-06 5.559391179941691 0.24789458237182294 LREDLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LREDLER 7 1 P62269;J3JS69 P62269 RPS18 40S ribosomal protein S18 0 ; 104.37 0.013430000000000001 44248800.0 39142.1 37463.6 41492.0 50361.0 54959.0 38448.0 46261.7 53628.0 42657.0 32927.8 False True 45768.08443828555 41182.73861969306 42481.32663928628 47539.43644256494 44190.1784764826 36431.71919616428 41879.45687029625 52220.32182356286 43280.77792588453 38897.34948367864 1.1766376127373377 1.0587543667203692 1.0921393669024024 1.2221767568639228 1.1360717134473348 0.9366118689256979 1.0766660820390577 1.3425162001198705 1.1126922142611588 1.0 15.247384230981174 LREDLER ddPTM_PC-9_Lapatinib_30min_R1 1 LREDLER 7 1 P62269;J3JS69 P62269 RPS18 40S ribosomal protein S18 0 90.37 0.020706 7382000.0 13581.0 10879.0 14823.0 13481.0 10670.0 13180.0 12026.0 10322.0 14004.0 11650.0 False True 13387.332449549633 10853.81034390377 13604.310158434686 14472.437711297682 10042.411578027119 12616.322124080625 12648.647436330084 10801.597802313609 12426.722051342427 13663.686977350771 0.9797745273102911 0.7943544346335865 0.9956544072610483 1.0591897878872307 0.7349708460588742 0.9233468349350888 0.9257126174872683 0.7905331716262657 0.9094706335077227 1.0 13.738059209166998 -6.247123458027898 24.991082686596577 0.8745847362284627 0.9483520037579518 0.13365461935362744 0.09365879145635703 1782.443405839431 3111581.977075417 0.027573278172209066 0.0354311567774157 5.660783455920332e-07 6.247123458027898 0.07376726752948914 LREETER ddPTM_PC-9_Lapatinib_30min_R1 1 LREETER 7 1 K7EMQ3;P50570-3;P50570-2;P50570-5;P50570-4;P50570 K7EMQ3 DNM2 Dynamin-2 0 81.191 0.031505 1704800.0 2613.5 3645.2 4808.3 2583.7 3708.5 3870.4 3213.1 3401.9 3261.6 2690.5 False True 2576.2310107427998 3636.759763360419 4412.980134574752 2773.713916970535 3490.3733211915264 3704.872014343068 3379.458596180957 3559.964693246529 2894.244261829366 3155.5493401340977 0.8164128438674074 1.1524965612503693 1.398482374668627 0.8789955782636134 1.1061064001753813 1.1740814720347952 1.0709572983692734 1.128160047434164 0.9171918895447766 1.0 11.623675466192767 -8.258446952703524 24.61593588574335 0.9585959420091449 1.0986065819318571 0.10592660568607937 0.15215489310377353 437.22168949796674 3596720.5685926634 0.11240754864265325 0.03825226893620626 5.515095629074434e-09 8.258446952703524 0.14001063992271223 LRELSTLAHCS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 LRELSTLAHCSR 12 1 E5RHR4;Q6ZUS5-2 E5RHR4 CCDC121 1 LRELS(0.057)T(0.047)LAHCS(0.896)R 51.998000000000005 0.046428 161220000.0 80787.0 59957.0 98550.0 142560.0 132890.0 100900.0 72377.0 101510.0 81678.0 93818.0 True False 106475.58552601137 79336.92772696125 97243.16260857382 109694.99453004415 114440.51734837214 94590.70704942776 78818.41278717226 85823.96196774331 85995.3323310581 90533.4603759769 1.1760909732581561 0.8763271325041868 1.0741129545334087 1.2116514057287904 1.2640687418012246 1.0448148856411927 0.8705998032091875 0.9479805765881975 0.9498734719067141 1.0 16.46616347778648 -7.007165885406935 24.912945330397438 0.940625469521242 1.1138864375949162 0.4072303356174096 0.10127537859628781 365.22483738966486 1269743.6639625188 0.03992278584260696 0.033826280785850926 9.836353194714312e-08 7.007165885406935 0.1732609680736742 LREQDCGEPAS(ph)PAASISR ddPTM_PC-9_AZD4547_30min_R2 1 LREQDCGEPASPAASISR 18 1 O60353-2;O60353 O60353-2 FZD6 Frizzled-6 1 LREQDCGEPAS(0.676)PAAS(0.184)IS(0.14)R 63.125 0.0089146 7776400.0 9568.7 11097.0 12845.0 17714.0 15325.0 11760.0 16125.0 18412.0 14052.0 12681.0 True False 12611.347558675836 14683.888236337532 12674.666907226092 13630.310978571835 13197.3882787554 11024.645340944187 17560.093761735832 15566.84846566928 14794.760032273434 12237.042049795991 1.030587907384537 1.1999540556112034 1.0357623072348106 1.1138566757478023 1.0784786245770412 0.9009240383486289 1.4349949677609046 1.2721087663442983 1.2090143984199258 1.0 13.578967250013713 -7.258450006598364 24.999967754869026 1.251705258660059 1.0684883007049129 0.30709626360428566 0.12215402501839265 298.3695174807032 2495264.9030471677 0.0465512136784585 0.03448595882319157 5.515056847870506e-08 7.258450006598364 -0.18321695795514614 LREQGTES(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 LREQGTESR 9 1 P42166;G5E972;P42167;H0YJH7;P42167-2;P42167-3 P42166;G5E972 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 LREQGT(0.058)ES(0.942)R 61.419 0.031106 1499600.0 3360.9 4444.4 3651.4 2067.7 2138.3 2899.6 3041.6 4136.9 3958.8 2561.7 True False 3312.972949686424 4434.109264863122 3351.1959868116064 2219.7655556449977 2012.5293980595495 2775.590867297735 3199.079165336902 4329.115476495946 3512.918255987886 3004.4864317493107 1.1026752907509394 1.4758293523999835 1.11539727768397 0.7388169679144057 0.6698414001116952 0.9238154108360193 1.0647673863763443 1.4408836833972296 1.1692242037992995 1.0 11.55290269134259 -9.631955051070891 12.823347264284491 0.9999988253269207 1.0745025411280467 0.008766111418807454 0.24616528088302042 0.0 0.0 0.27100664377825384 0.06572876573775766 2.3336995847349714e-10 9.631955051070891 0.07450371580112591 LREQGTESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LREQGTESR 9 1 P42166;G5E972;P42167;H0YJH7;P42167-2;P42167-3 P42166;G5E972 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 0 73.84100000000001 0.036952 453430.0 947.8 2178.9 2259.4 2821.6 3433.7 3651.0 1081.5 3508.0 3352.8 2642.9 False True 1108.2438200967008 2395.206792151559 2313.272664822215 2663.5148997506235 2760.8911340216932 3459.5351327818303 979.0524906180573 3415.918717033235 3401.8283571255724 3122.036848815112 0.3549746123327487 0.7671936329196747 0.7409498275781586 0.8531337164586931 0.8843236860159155 1.1081019540479822 0.31359414959808407 1.0941314540632852 1.0896182594438781 1.0 11.60827184993726 -4.589019068287966 1.1722548985226189 0.8894911243563418 2.1434879463485907e-27 0.34272537201511344 0.22205712385404328 2.888698612169187 2.512833826866298 0.06791301370312322 3.504277331384104 2.5762080426129052e-05 4.589019068287966 -0.8894911243563418 LREQGTESR ddPTM_PC-9_Lapatinib_30min_R1 3 LREQGTESR 9 1 P42166;G5E972;P42167;H0YJH7;P42167-2;P42167-3 P42166;G5E972 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 0 ;; 107.45 0.0028336 758000.0 23626.4 14205.099999999999 15450.4 11046.2 13234.7 12585.1 9429.9 9841.7 14896.2 6343.200000000001 False True 23289.483203448883 14172.208963708747 14180.12775226873 11858.574397042978 12456.260966421325 12046.864610300994 9918.134081144937 10298.981310892252 13218.433092059908 7439.6136682172855 3.1304694359256446 1.9049657140469172 1.906030122618805 1.5939771775655367 1.6743155655562625 1.6192863161384723 1.3331517634465508 1.3843435654314213 1.7767633752986758 1.0 12.861011990213356 -1.7313625462880926 0.7515076556543969 1.479847136616593 199.9999999999996 0.8309933153717157 0.220191281678213 99.18180893287945 0.6053368129501262 0.07784639921990677 33084.23497541949 0.018562542188304745 1.7313625462880926 198.520152863383 up LREQVEER ddPTM_PC-9_AZD4547_30min_R2 2 LREQVEER 8 1 O00567;H0Y653;H0YDU4;A0A494C128 O00567 NOP56 Nucleolar protein 56 0 ; 96.665 0.0078426 5935900.0 9499.900000000001 13890.099999999999 16481.6 23685.0 20104.7 16344.8 13240.0 14299.1 12268.3 15081.8 False True 12520.670589804742 18379.803189290073 16263.043215113861 18224.789179602216 17313.50943738294 15322.757072165348 14418.334350721383 12089.502655629563 12916.777291769145 14553.790772542641 0.8603030499398405 1.2628876886127587 1.117443796553398 1.2522365797634885 1.1896219828889405 1.0528361518755271 0.9906927051557721 0.8306772334832356 0.8875197873627602 1.0 13.82910735511948 -7.2513746997143835 2.135796539078953 0.898067444836067 1.1467135952329612 0.42988956234698184 0.11362666834122247 0.27776590339873897 2.478239062448663 0.054439789116167134 0.03541705379697604 5.60564124952926e-08 7.2513746997143835 0.2486461503968942 LREQVEER ddPTM_PC-9_Lapatinib_30min_R1 1 LREQVEER 8 1 O00567;H0Y653;H0YDU4;A0A494C128 O00567 NOP56 Nucleolar protein 56 0 76.221 0.032747000000000005 3401700.0 15676.0 13648.0 15084.0 10893.0 13285.0 13154.0 13427.0 14113.0 12670.0 9829.9 False True 15452.457365373672 13616.398894530626 13843.851745923823 11694.10755798276 12503.602419314926 12591.434083471662 14122.18436118443 14768.741502039524 11242.971178985177 11528.985117481567 1.3403137577082034 1.181057895016612 1.2007866785197068 1.0143223743303142 1.084536261596481 1.0921545960172234 1.2249286660775334 1.281009677048283 0.9751917505676452 1.0 13.492977899441223 -4.608601933865323 1.3635658667474242 1.116090036717267 1.5049073016619228 0.3595706299907313 0.09486530783508151 2.327555575893845 2.89489352631382 0.028152694174772955 1.3988869756084183 2.462623764529164e-05 4.608601933865323 0.38881726494465574 LREQVVK ddPTM_PC-9_AZD4547_30min_R2 1 LREQVVK 7 1 P15121;E9PCX2;E9PEF9 P15121 AKR1B1 Aldose reductase 0 89.75200000000001 0.021244 2999000.0 16450.0 14288.0 21024.0 22055.0 19167.0 16154.0 24425.0 33656.0 22385.0 20957.0 False True 21680.7578187442 18906.31658293148 20745.208023162435 16970.560496353257 16505.992896502754 15143.887826327575 26598.777682505282 28455.23853794077 23568.22540011677 20223.30180881434 1.0720681530497966 0.9348778335835916 1.0258071713156465 0.8391587415738723 0.816186844885468 0.7488335964865589 1.3152539547677713 1.4070520633548838 1.1653994794185658 1.0 14.303730941296733 -7.271383209490166 24.993988257891957 1.2558473990689802 0.9057648902908182 0.5659097151091725 0.1341764774222544 485.0338289981624 1219135.8571607785 0.05673891094743359 0.038766878407479693 5.353240938180889e-08 7.271383209490166 -0.35008250877816205 LREQYGLGPYEAVT(ph)PLTK ddPTM_PC-9_AZD4547_30min_R2 1 LREQYGLGPYEAVTPLTK 18 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 LREQYGLGPYEAVT(0.996)PLT(0.004)K 86.959 0.0012188 15043000.0 59785.0 40719.0 81636.0 86880.0 82257.0 76119.0 69902.0 90669.0 68503.0 76208.0 True False 78795.38639474893 53880.62044655562 80553.45329998514 66851.15828261939 70837.03540917349 71359.26689688195 76123.1425818826 76658.18941634631 72123.92872835377 73539.98111590985 1.0714632394391805 0.7326711215989004 1.095369512986698 0.9090450836158377 0.9632452216369743 0.9703465491024431 1.03512594682206 1.0424015379541873 0.9807444553823835 1.0 16.166241185625786 -7.037962386113803 2.967284860017303 1.017823147198724 0.9475742788946858 0.08145146869329922 0.09370337331470993 0.6186136201675552 10.912014215690334 0.03596731516919978 0.028349402282796483 9.16299846657979e-08 7.037962386113803 -0.0702488683040382 LREQYGLGPYEAVT(ph)PLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LREQYGLGPYEAVTPLTK 18 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 LREQYGLGPY(0.001)EAVT(0.976)PLT(0.023)K;LREQYGLGPY(0.001)EAVT(0.996)PLT(0.003)K 64.454 0.011478 9882100.0 47089.0 41085.0 56781.0 66052.0 80214.0 71238.0 79052.0 71398.0 72878.0 52333.0 True False 55060.23764985604 45163.647278694254 58134.87438314164 62351.32058347336 64496.64252101707 67502.15387266826 71563.62227308247 69523.8781524342 73943.70287836957 61820.55863219991 0.8906460709524763 0.7305603229403734 0.9403809294091604 1.0085855249938973 1.0432879279648453 1.091904624710218 1.1576023228591108 1.124607730675244 1.1961021465091581 1.0 15.915799070501702 -5.8407982202455315 1.0813544617604431 1.1243356271629645 0.7975700207032193 0.7563167754617447 0.06510704324913498 0.24766785458995835 0.5701967642522693 0.024028950550435378 0.06103483322662543 1.4427855357045852e-06 5.8407982202455315 -0.3267656064597453 LRESTPGDS(ph)PSTVNK ddPTM_PC-9_AZD4547_30min_R2 1 LRESTPGDSPSTVNK 15 1 Q5T6F2 Q5T6F2 UBAP2 Ubiquitin-associated protein 2 1 LRES(0.002)T(0.383)PGDS(0.613)PS(0.001)TVNK 102.72 0.012429 0.0 8464.6 6319.2 10126.0 14036.0 12174.0 9812.3 5431.0 11727.0 8109.9 8722.2 True False 11156.166725382504 8361.757821308833 9991.72262378913 10800.21705403829 10483.85023853626 9198.735329842404 5914.348478758905 9914.861609651512 8538.572757311002 8416.838432831059 1.325458105726054 0.9934559024790857 1.1871111348431038 1.2831679187176184 1.2455805493001426 1.0928967454051923 0.7026805285567986 1.1779793195242056 1.0144631889338758 1.0 13.03906270871233 -7.002425262898471 24.18933002673109 0.9756375687737654 1.1953267088023138 0.39320007804592527 0.13621443095144814 70.0756480843473 698938.2958579225 0.048632776455139554 0.04213750056846554 9.944311894364464e-08 7.002425262898471 0.21968914002854845 LRGQS(ph)TDSLPQTICR ddPTM_PC-9_Lapatinib_30min_R1 1 LRGQSTDSLPQTICR 15 1 Q96NE9-3;Q96NE9-2;Q96NE9 Q96NE9-3 FRMD6 FERM domain-containing protein 6 1 LRGQS(0.902)T(0.097)DS(0.001)LPQTICR 108.25 0.0064757999999999994 0.0 30840.0 28018.0 24532.0 24457.0 22233.0 27746.0 21021.0 20717.0 28721.0 19190.0 True False 30400.215944636657 27953.12604242079 22515.07365625851 26255.649366160324 20925.298651759804 26559.368259085037 22109.364523457065 21679.58745112681 25486.13853446199 22506.9659309323 1.3507025352918103 1.2419766452840095 1.0003602318211655 1.1665565872686574 0.9297254332713615 1.1800510268948932 0.9823342955822938 0.9632390042112078 1.1323666909467918 1.0 14.458083965820736 -5.0839043357391365 3.1676264568484367 1.0457225783674393 1.3413639888415478 0.6030683102609256 0.08360302688970378 0.16096384893636628 2.987832260562774 0.020675638685612147 0.07982956083394205 8.243196721150422e-06 5.0839043357391365 0.2956414104741085 LRLCDDGPQLPTS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 LRLCDDGPQLPTSPR 15 1 O60504-2;O60504;H0YAZ3;H0YB51 O60504-2 SORBS3 Vinexin 1 LRLCDDGPQLPT(0.007)S(0.993)PR;LRLCDDGPQLPT(0.028)S(0.972)PR 133.9 2.0113e-05 10956000.0 104652.0 44016.0 95782.0 58098.0 61319.0 73040.0 39207.0 35512.0 88424.0 37645.0 True False 103159.64328917369 43914.08365633496 87907.17368921202 62370.72072924653 57712.33697779241 69916.24946455608 41236.94661867564 37162.017162929755 78464.75797400056 44151.888091190514 2.3364718418408206 0.9946139464213988 1.9910173152199093 1.4126399441950743 1.3071318005380514 1.5835392887423596 0.9339792339912076 0.8416857980382627 1.7771552104847896 1.0 15.430187513494625 -1.5228787452803376 0.3157877144752978 1.1392255855076172 8.937451427482861 0.30381937328686115 0.3967491188376113 75.50429156182517 1.078058809667766 0.3691839016388984 338.50236889557726 0.029999999999999995 1.5228787452803376 7.798225841975244 LRLDT(ph)GSPEPETR ddPTM_PC-9_AZD4547_30min_R2 2 LRLDTGSPEPETR 13 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 LRLDT(0.694)GS(0.306)PEPETR;LRLDT(0.499)GS(0.499)PEPET(0.003)R 137.93 0.00063731 26681000.0 41501.0 35223.0 49315.0 76097.0 61955.0 49319.0 43966.0 50608.0 39271.0 48259.0 True False 54697.45472557464 46608.14592669342 48661.05087815142 58554.012336930115 53353.617671144544 46235.07513350564 47878.88882657223 42787.6964561477 41346.78488666452 46569.4670988964 1.1745346926435165 1.0008305619584368 1.0449131997755798 1.257347699783271 1.1456780804006435 0.9928195019994402 1.028117601708757 0.9187929156518452 0.8878517935122422 1.0 15.507096752835492 -7.144684010132629 1.716468934544497 0.938185834749613 1.117950833288299 0.5160633542531059 0.07608269124097894 0.3272173487942384 1.9015021746693441 0.0413675628336928 0.02796217515766233 7.166646611512987e-08 7.144684010132629 0.179764998538686 LRLDT(ph)GSPEPETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LRLDTGSPEPETR 13 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 LRLDT(0.5)GS(0.5)PEPETR;LRLDT(0.463)GS(0.463)PEPET(0.074)R 107.93 0.009827200000000001 15876000.0 54584.0 42974.0 63153.0 69800.0 85003.0 73781.0 67968.0 69578.0 65462.0 52435.0 True False 63823.99311685832 47240.17471472813 64658.80702908623 65889.33229465332 68347.27234914116 69911.79447597268 61529.578994293275 67751.65122398484 66419.2579080632 61941.05042476835 1.03039894672721 0.7626634419463802 1.0438765017009 1.0637425720553517 1.103424496040047 1.1286827394198835 0.9933570479084006 1.0938085608714994 1.072297893764878 1.0 15.91860822865428 -5.433926417715832 8.595161447799766 1.0689874638108596 0.8968346376009091 0.4612638810805274 0.07192576682623351 0.2579077403616361 22.925985621371446 0.01745893056145835 0.036416814106706934 3.6819135082377763e-06 5.433926417715832 -0.17215282620995054 LRLDT(ph)GSPEPETR ddPTM_PC-9_Lapatinib_30min_R1 1 LRLDTGSPEPETR 13 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 LRLDT(0.5)GS(0.5)PEPET(0.001)R 155.14 0.0018617999999999998 15796000.0 64536.0 37806.0 44726.0 39248.0 37827.0 38469.0 34838.0 35929.0 45014.0 29800.0 True False 63615.70480554704 37718.4625297937 41048.80092735276 42134.428847489864 35602.09023074341 36823.77054561891 36641.741176356845 37598.39250526309 39944.049301565814 34950.890293995944 1.8201454747055554 1.079184599090833 1.1744708241210196 1.2055323481910831 1.0186318554769214 1.0535860527691536 1.0483779059170737 1.0757492066438703 1.1428621407228536 1.0 15.093041584974879 -4.760785937259757 24.999960936634228 1.0928603611576464 1.820146308880692 0.9232938627407894 0.0632371244059398 4.136146923344585 158125.61670495413 0.01649565965939559 0.09570608026424395 1.734658796359744e-05 4.760785937259757 0.7272859477230456 LRLDTGPQSLS(ph)GK ddPTM_PC-9_AZD4547_30min_R2 2 LRLDTGPQSLSGK 13 1 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 LRLDTGPQS(0.007)LS(0.993)GK;LRLDTGPQS(0.064)LS(0.936)GK 81.65100000000001 0.0053768 29818000.0 66595.0 80405.0 82619.0 104152.0 79910.0 85493.0 66984.0 76144.0 66365.0 72873.0 True False 87770.8247379497 106394.34384452717 81523.41807770438 80141.36553235925 68815.87584700462 80147.10919501197 72945.4462347976 64377.69441505114 69872.91841316724 70321.73845081497 1.248132180340495 1.512965210877749 1.1592918473527811 1.1396385711996073 0.9785861010125113 1.1397202481145876 1.0373100529335992 0.9154735908595141 0.9936176202759599 1.0 16.101683115892087 -5.638357770381064 1.8016555286623734 1.0169150432192582 1.3810034176787456 0.7069802417349486 0.08921497094441758 0.1851562635017751 1.2022974441737044 0.02668392303460435 0.0638167853704781 2.2995466778399496e-06 5.638357770381064 0.3640883744594874 LRLDTGPQSLS(ph)GK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LRLDTGPQSLSGK 13 1 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 LRLDTGPQS(0.081)LS(0.919)GK;LRLDTGPQS(0.012)LS(0.988)GK 74.14699999999999 0.0093459 30982000.0 116824.0 137822.0 111527.0 143346.0 121761.0 99059.0 98784.0 70202.0 68288.0 67018.0 True False 136599.9958208237 151504.0573261335 114186.22664850276 135314.7883540024 97902.80611865214 93864.17165659698 89426.46438577378 68359.27188516737 69286.58281179631 79167.83288580409 1.725448213517008 1.913707269778005 1.442331089360638 1.7092142530816485 1.236648807349222 1.185635228792882 1.1295808048044877 0.8634728196207219 0.8751860482494067 1.0 16.27262673961617 -6.4628891228574314 0.7118144527948201 0.8948430095271582 1.8272498191316975 0.8759753494796092 0.12460376051139642 0.22776924422279388 0.2560843126231694 0.07900889525183401 0.11155185228671628 3.4443785592056603e-07 6.4628891228574314 0.9324068096045393 LRLDTGPQSLS(ph)GK ddPTM_PC-9_Lapatinib_30min_R1 2 LRLDTGPQSLSGK 13 1 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 LRLDTGPQS(0.014)LS(0.986)GK;LRLDTGPQS(0.089)LS(0.911)GK 116.13 0.0001315 39541000.0 267280.0 245754.0 232143.0 174590.0 144703.0 122039.0 112915.0 114135.0 96805.0 74597.0 True False 263468.53818685113 245184.9717120812 213057.098637894 187429.93101516625 136191.85403704393 116819.67645680383 118761.18620266172 119438.12877030278 85901.80149815786 87490.99205574555 3.0113790230996598 2.8024024639686305 2.4351889678213166 2.142276897440411 1.5566385845787216 1.3352194747359967 1.3574104420600481 1.3651477250846793 0.9818359522478026 1.0 16.416846866374513 -5.826792738288055 0.6556322968180036 1.1057176364523298 3.2823979211492618 0.9784029449238372 0.10352526233401216 0.15735171656124122 0.1175771358973369 0.06232573970729795 0.2154941038832316 1.490072026640553e-06 5.826792738288055 2.176680284696932 up LRLDTGS(ph)PEPETR ddPTM_PC-9_AZD4547_30min_R2 1 LRLDTGSPEPETR 13 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 LRLDT(0.097)GS(0.901)PEPET(0.002)R 68.329 0.015606 22314000.0 19997.0 17605.0 50729.0 100710.0 75561.0 53519.0 34023.0 65690.0 40439.0 47192.0 True False 26355.630036560964 23295.47196546114 50056.3003142602 77492.86545398943 65070.659427800034 50172.44846955712 37050.98108871555 55539.11990602948 42576.52298214525 45539.82244412685 0.5787380938715097 0.5115406849476088 1.099176448825084 1.7016505839271996 1.4288738061646094 1.1017269233123181 0.8135952030593373 1.219572605364697 0.9349294902144757 1.0 15.474841046090365 -5.298754647283817 5.317459732759146 1.187818929052606 0.5417544267759397 0.5137707812673145 0.23998547303638074 0.14712954642428377 11.264435062484564 0.06933190524757468 0.15540431870135402 5.026264658910051e-06 5.298754647283817 -0.6460645022766663 LRLDTGS(ph)PEPETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LRLDTGSPEPETR 13 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 LRLDT(0.107)GS(0.893)PEPETR;LRLDT(0.013)GS(0.986)PEPET(0.001)R 70.41 0.013338 22197700.0 47641.0 46571.0 92467.0 78697.0 100322.0 88866.0 74493.0 78269.0 82880.0 51870.0 True False 55705.680347359084 51194.26110298333 94671.76396305033 74287.8622291165 80664.62426750298 84205.71052034783 67436.48375738417 76214.52168286036 84091.96320644455 61273.62039730596 0.9091298993948188 0.8355024686159104 1.5450656146835546 1.2123955096406012 1.3164657766990637 1.3742571431938782 1.1005793899579854 1.2438390483323116 1.3724007600853605 1.0 15.902978476089599 -5.238689864582576 24.910275462124204 1.2765195256266426 0.8723160617046375 0.5496341762644572 0.14414124719553148 525.6409530472207 575564.5153098451 0.03474726885107454 0.09179012616883583 5.771784870289616e-06 5.238689864582576 -0.4042034639220051 LRLDTGS(ph)PEPETR ddPTM_PC-9_Lapatinib_30min_R1 1 LRLDTGSPEPETR 13 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 LRLDT(0.081)GS(0.919)PEPETR 79.471 0.006529699999999999 19109000.0 51355.0 29630.0 78913.0 31363.0 34314.0 55332.0 35857.0 25988.0 66545.0 33902.0 True False 50622.668282646395 29561.39355546179 72425.07775298893 33669.539643900986 32295.717983919632 52965.579345191865 37713.500010351534 27195.497353858354 59050.001350084334 39761.91552842453 1.2731446060856364 0.7434599958930371 1.821468528124973 0.8467786120573518 0.8122274179882619 1.3320681018832823 0.9484829769680324 0.6839584308863882 1.4850894521887752 1.0 15.279099639890076 LRLDVS(ph)ITGEPPPVAT(ph)WLK ddPTM_PC-9_AZD4547_30min_R2 1 LRLDVSITGEPPPVATWLK 19 1 Q14324 Q14324 MYBPC2 Myosin-binding protein C, fast-type 2 LRLDVS(0.968)IT(0.032)GEPPPVAT(1)WLK 77.89399999999999 0.011941 16914000.0 22212.0 26478.0 22120.0 34058.0 24545.0 20086.0 17358.0 26043.0 19513.0 17122.0 True False 29274.95396169884 35036.49569448908 21826.674347048756 26206.454290854665 21137.35042754003 18830.019244745323 18902.82837309834 22018.65275860444 20544.41734342096 16522.563991531195 1.7718166488387643 2.1205241336905933 1.321022231067541 1.5861009407672468 1.2793020767463326 1.139654792948409 1.1440614412380048 1.3326413969339335 1.2434158133054414 1.0 14.012149962846756 -5.544878638243073 0.9795246824933336 1.1921264026661222 2.0145908230534784 0.7111350607406461 0.17289261623982952 0.4106436813472337 0.6525105828305595 0.06299682652572046 0.2774407412923341 2.851815083833974e-06 5.544878638243073 0.8224644203873561 LRLS(ph)PS(ph)PTSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LRLSPSPTSQR 11 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 LRLS(1)PS(0.963)PT(0.03)S(0.007)QR 78.191 0.031127999999999996 0.0 9646.8 11061.0 11755.0 9019.2 12289.0 10311.0 11540.0 8680.6 9765.0 9172.3 True False 11279.81270701504 12159.062980397635 12035.283781085755 8513.883464640923 9881.05866732464 9770.2730085219 10446.847657635128 8452.74344785596 9907.794651434991 10835.165382113144 1.0410374285228656 1.1221852691302712 1.1107614287968124 0.7857640529138367 0.911943502370203 0.9017188629765462 0.9641613477244143 0.7801213133128432 0.9144110220773307 1.0 13.403433553667107 -5.745800339634118 24.994754750172532 0.8888460559006813 1.094413857615362 0.6407626919383942 0.06761279797577516 139.13138318717736 222361.90576071516 0.017658329180589804 0.03044967750017375 1.795558918357563e-06 5.745800339634118 0.2055678017146806 LRLS(ph)PS(ph)PTSQR ddPTM_PC-9_Lapatinib_30min_R1 1 LRLSPSPTSQR 11 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 LRLS(1)PS(0.993)PT(0.005)S(0.001)QR 90.229 0.028489999999999998 70012000.0 115520.0 99109.0 114590.0 85047.0 99309.0 108040.0 99760.0 97754.0 121140.0 64232.0 True False 113872.6636162263 98879.5191997388 105168.85253019152 91301.64008847512 93467.83986900609 103419.38105354104 104925.08467057128 102296.0077085218 107495.93753924748 75334.41561623992 1.5115623143120083 1.3125411326403553 1.3960266588637367 1.2119512621372632 1.2407057133772619 1.3728039197963438 1.3927908488076526 1.3578920984749732 1.4269167240486893 1.0 16.201021472811423 -10.657889197517603 4.042221311105435 0.9998970619563424 1.3515965779885042 0.6259643406414963 0.08291288939145262 61035674.143622525 116609962.5261595 89341.19246299722 0.021334014082168177 2.1984206890249767e-11 10.657889197517603 0.35169951603216176 LRLS(ph)PSPT(ph)SQR ddPTM_PC-9_Lapatinib_30min_R1 1 LRLSPSPTSQR 11 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 LRLS(0.917)PS(0.086)PT(0.98)S(0.018)QR 132.97 0.018177000000000002 95379000.0 394740.0 314510.0 359450.0 327020.0 362330.0 345710.0 339390.0 314590.0 334570.0 313110.0 True False 389110.9352135498 313781.77141843736 329897.4085171257 351070.1417067406 341018.4617681881 330924.7891893708 356961.9535519764 329206.99986725854 296887.2034217109 367230.64630715095 1.0595818707573175 0.8544542090204283 0.8983384470619595 0.9559935839698582 0.9286220123441468 0.9011360912198652 0.9720374841848416 0.8964584061209055 0.8084488764954411 1.0 18.48632693468756 -7.975431333080489 23.71803110542654 0.8869674986205285 0.932769001562407 0.04368090492228449 0.06740988613543963 306.266046018831 295661.49229856156 0.034800763061830685 0.01671612169414126 1.0582022166304836e-08 7.975431333080489 0.04580150294187857 LRLS(ph)PSPTSQR ddPTM_PC-9_AZD4547_30min_R2 3 LRLSPSPTSQR 11 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 LRLS(0.924)PS(0.064)PT(0.011)SQR;LRLS(0.929)PS(0.071)PTSQR;LRLS(0.775)PS(0.225)PT(0.001)SQR 163.71 0.0005946 1232544000.0 249390.0 236907.0 296048.0 421995.0 326490.0 299130.0 226890.0 344309.0 269447.0 295219.0 True False 328690.83236575214 313482.5547811137 292122.21008567326 324710.5725077578 281162.4991276253 280425.3538126392 247082.77045582948 291103.95548371307 283689.4183330472 284883.47266766947 1.1537729068235072 1.100388702249521 1.025409467773682 1.1398013702484897 0.9869386121097139 0.984351079361382 0.8673117051759041 1.0218351831989219 0.9958086219483319 1.0 18.12001240149688 -6.3524742325740435 5.520653808363842 0.9706184801648938 1.0985589231856365 0.6110904019067622 0.05021393941520466 0.16264038906363568 7.74925822525872 0.016105284916295898 0.018333392031225547 4.441460125177777e-07 6.3524742325740435 0.1279404430207427 LRLS(ph)PSPTSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LRLSPSPTSQR 11 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 LRLS(0.935)PS(0.062)PT(0.002)SQR;LRLS(0.922)PS(0.078)PTSQR 169.09 0.007865 1441960000.0 376390.0 328530.0 413970.0 414800.0 457260.0 381790.0 369700.0 434980.0 360840.0 336160.0 True False 440105.39295863826 361144.28722086863 423840.6147899682 391560.1007997452 367663.185468376 361768.2602971172 334679.33960378706 423562.23589940544 366116.60235778906 397103.1469589035 1.1082898645579988 0.9094470542139614 1.0673312917206161 0.9860412938008472 0.9258631876478826 0.9110183665569309 0.8428020330909723 1.0666302675844574 0.9219685242022992 1.0 18.599154268399204 -4.749299411748844 24.795602260602507 0.9591560175897054 1.1082902423739693 0.30150934678609254 0.06816263545213246 674.0443514117176 1376625.8112450596 0.017121902304241318 0.2824457682481902 1.781150381529376e-05 4.749299411748844 0.14913422478426397 LRLS(ph)PSPTSQR ddPTM_PC-9_Lapatinib_30min_R1 1 LRLSPSPTSQR 11 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 LRLS(0.668)PS(0.322)PT(0.004)S(0.007)QR 89.46 0.044743 92667000.0 35863.0 26262.0 29561.0 24035.0 26634.0 21532.0 21217.0 22669.0 22620.0 19287.0 True False 35351.58704353125 26201.19195253247 27130.608688759883 25802.614078409577 25067.440484458708 20611.12655354354 22315.512444421704 23722.28449725316 20072.297400840165 22620.73225168793 1.56279587460717 1.1582822192052324 1.1993691621868445 1.1406621939254076 1.1081622029538063 0.9111608910010226 0.9865070766113926 1.0486965776929276 0.8873407446543822 1.0 14.465358010856853 -1.5228787452803894 0.4517334203165765 0.9698872277631766 13.346250128310245 0.8329659825716652 0.07486729321075486 34.75001146791473 0.4169712118167578 0.046658554703888216 397.1250233199819 0.029999999999996422 1.5228787452803894 12.376362900547068 LRLS(ph)VDEVSSPSTPEAPDIPACPSPGQK ddPTM_PC-9_AZD4547_30min_R2 1 LRLSVDEVSSPSTPEAPDIPACPSPGQK 28 1 Q9H211 Q9H211 CDT1 DNA replication factor Cdt1 1 LRLS(0.43)VDEVS(0.22)S(0.176)PS(0.087)T(0.087)PEAPDIPACPSPGQK 51.976000000000006 0.0050041 3558600.0 17003.0 17245.0 20497.0 27501.0 19211.0 19949.0 19085.0 20287.0 15709.0 19799.0 True False 22409.60031562965 22819.109005644827 20225.196387498105 21161.06933621452 16543.884255998033 18701.58587640268 20783.528027456025 17152.110298882948 16539.34566944089 19105.843036346585 1.172918686341035 1.1943523749375622 1.0585869646799717 1.1075705634113142 0.8659070539062458 0.9788411765356361 1.0878100478433663 0.8977416105770945 0.8656695042441602 1.0 14.22172629689015 -5.757245263022611 1.3345986788272215 0.9533931391027417 1.1857679580959326 0.6013751542749934 0.07255395739988602 0.33052678865223745 1.17158845694893 0.02563227954396877 0.06355661531011453 1.7488587609779273e-06 5.757245263022611 0.2323748189931909 LRLSPS(ph)PTS(ph)QR ddPTM_PC-9_Lapatinib_30min_R1 1 LRLSPSPTSQR 11 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 LRLS(0.414)PS(0.641)PT(0.461)S(0.484)QR 119.17 0.029556 18845000.0 80268.0 75629.0 68984.0 64072.0 85074.0 69368.0 58416.0 70148.0 87449.0 56437.0 True False 79123.36360065154 75453.885697132 63312.40180594067 68784.0686179262 80070.11458191932 66401.29234470589 61440.49464831683 73407.33216786424 77599.57274120557 66192.06025242458 1.1953603392750312 1.1399235106051586 0.9564954099403724 1.0391589014697074 1.209663429066425 1.0031609847387042 0.9282154749982465 1.1090050965013643 1.1723395894504303 1.0 16.014370555472908 LRLSVDEVSS(ph)PSTPEAPDIPACPSPGQK ddPTM_PC-9_AZD4547_30min_R2 1 LRLSVDEVSSPSTPEAPDIPACPSPGQK 28 1 Q9H211 Q9H211 CDT1 DNA replication factor Cdt1 1 LRLS(0.175)VDEVS(0.319)S(0.434)PS(0.015)T(0.056)PEAPDIPACPSPGQK 81.548 8.6631e-05 0.0 10833.0 8856.1 12787.0 15624.0 13514.0 10300.0 8558.6 10812.0 7690.8 8378.7 True False 14277.668659602183 11718.661134525437 12617.436025122617 12022.128188393704 11637.81436861993 9655.939371745337 9320.298819794869 9141.253835043242 8097.319986920613 8085.3642632777955 1.7658658527542994 1.4493671222395499 1.5605278394726927 1.486900008079531 1.4393679727550055 1.1942491466464658 1.152737034016626 1.1305927027383416 1.001478687076242 1.0 12.981097056380362 -6.7473703302135375 0.5936236985370262 0.9874365339654702 1.6513559821138692 0.9070971402308449 0.07459660843974082 0.23930519189862273 0.18384764445853508 0.05982072166194743 0.06933073446918875 1.7890796251021643e-07 6.7473703302135375 0.6639194481483991 LRLVPT(ph)GARAIVDMSY(ph)AR ddPTM_PC-9_AZD4547_30min_R2 1 LRLVPTGARAIVDMSYAR 18 2 Q8N4Q0 Q8N4Q0 ZADH2 Zinc-binding alcohol dehydrogenase domain-containing protein 2 2 LRLVPT(1)GARAIVDMS(0.267)Y(0.733)AR 61.18600000000001 0.042581 0.0 9411.2 10566.0 14058.0 22146.0 15838.0 17970.0 13517.0 19686.0 14282.0 12707.0 True False 12403.765834879348 13981.252870608481 13871.581734665975 17040.58185228925 13639.167083779965 16846.333059248886 14719.986814101287 16643.981039276867 15036.917362719129 12262.131797709775 1.0115505231476982 1.1401975693345419 1.131253681130454 1.3896916240512076 1.112299827533038 1.373850268221331 1.2004427172158245 1.35734807893563 1.2262890018461232 1.0 13.581922195986342 -5.0784230801260275 1.496678161531904 1.249354593687971 0.9978221268797034 0.23353187799135433 0.11838042985917997 0.838723658802039 2.58613943811312 0.0319888458091251 0.2661686026752395 8.34789388535813e-06 5.0784230801260275 -0.2515324668082677 LRPISDDSES(ph)IEESDTR ddPTM_PC-9_Lapatinib_30min_R1 1 LRPISDDSESIEESDTR 17 1 D6R9S4;Q09GN1;Q71F23-3;Q71F23 D6R9S4 CENPU;MLF1IP Centromere protein U 1 LRPISDDS(0.001)ES(0.998)IEES(0.002)DTR 121.0 0.00020489 0.0 7839.1 6782.8 7737.8 8394.1 8578.2 8882.2 5692.9 8017.5 12050.0 8273.9 True False 7727.31299648512 6767.094843333986 7101.62795277177 9011.430115896732 8073.647141390088 8502.329011419486 5987.650506426371 8390.022319322745 10692.80210787462 9704.032590721243 0.7962991595755549 0.697348734154553 0.7318223518295035 0.9286273548290882 0.8319888732762409 0.8761645153118307 0.617027040093787 0.8645913171545897 1.1018926418382822 1.0 13.244368680379472 -8.110428015192745 4.761702148534504 1.045064371066399 0.7857401434971929 0.5939739354961251 0.08724974860784743 0.1614306865318829 5.561278797082769 0.06479567036643306 0.023252105337793573 7.754824698142059e-09 8.110428015192745 -0.25932422756920603 LRPLS(ph)YPQTVGETYGK ddPTM_PC-9_AZD4547_30min_R2 2 LRPLSYPQTVGETYGK 16 1 P63000-2 P63000-2 1 LRPLS(0.998)YPQT(0.001)VGETYGK;LRPLS(0.999)Y(0.001)PQTVGETYGK 78.27199999999999 0.0046755 76244000.0 161960.0 289716.0 312177.0 340809.0 283932.0 214532.0 238441.0 309482.0 200259.0 206786.0 True False 213459.91102272357 383361.03129483364 308037.32900717185 262240.75049656123 244512.94282307214 201117.28012614313 259661.7870785767 261658.66808886896 210844.2819031489 199546.48508076012 1.0697252368856933 1.921161533562871 1.5436870706216825 1.3141837621967012 1.2253432713891868 1.0078718251777137 1.3012596386926425 1.3112667355827936 1.0566173682178182 1.0 17.606365341102496 -5.955411969325176 2.682783128516673 1.1678460002339495 1.552408693855219 0.34861359866445796 0.21844061417255844 0.2881900635209655 4.208254474146943 0.06436921639145451 0.09997709803319728 1.1081231570915605e-06 5.955411969325176 0.3845626936212696 LRPLS(ph)YPQTVGETYGK ddPTM_PC-9_Lapatinib_30min_R1 2 LRPLSYPQTVGETYGK 16 1 P63000-2 P63000-2 1 LRPLS(0.962)Y(0.038)PQTVGETYGK;LRPLS(1)YPQTVGETYGK 119.18 5.3371999999999997e-05 44980000.0 230550.0 256150.0 118314.0 52266.0 140550.0 93972.0 88542.0 81591.0 186550.0 54329.0 True False 227262.3147223076 255556.90041280934 108586.67962524715 56109.81599426485 132283.1253319316 89953.03661943131 93126.2715206667 85382.01572258957 165538.77454141175 63719.69526115792 3.566594500975926 4.010642225537934 1.704130554614236 0.8805725728018056 2.0760162896222827 1.4116991026205463 1.4614990096701603 1.3399627128260374 2.597921629457642 1.0 15.959451746753734 -5.280912924583478 7.909611281188773 1.5543212837846627 3.7908907416445676 0.7744306869583741 0.48136511255641234 0.07561958947819716 25.985672930664414 0.11997871708163549 0.26258551135313407 5.237054282422187e-06 5.280912924583478 2.236569457859905 LRPQSAQSSFPPS(ph)PGPSPDVQLATLAQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LRPQSAQSSFPPSPGPSPDVQLATLAQR 28 1 Q9Y679-3;Q9Y679 Q9Y679-3 AUP1 Ancient ubiquitous protein 1 1 LRPQSAQSSFPPS(0.997)PGPS(0.003)PDVQLATLAQR 96.133 4.9765e-05 0.0 4425.3 4315.5 1375.6 4041.8 4781.6 5302.0 5266.8 5207.8 5338.4 2060.6 True False 5174.415886340926 4743.914319854081 1408.3995209920517 3815.351049692402 3844.679805002804 5023.953786362438 4767.890575670077 5071.100768120212 5416.464000739433 2434.1704682993764 2.125740967499294 1.9488833594996322 0.5785952706821 1.5674132520217379 1.57946202004861 2.0639284930082993 1.958733226683645 2.0832973015497624 2.2251785860024933 1.0 11.249214490165823 -6.678079217792407 5.951273999510691 1.9388116892075389 1.5219837792599238 0.07668348518829049 0.49401983086975926 0.44336650546219086 24.76820508334108 0.16696072598441947 0.1659292807960994 2.0985570599238972e-07 6.678079217792407 -0.4168279099476151 LRPVS(ph)PEEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LRPVSPEEIR 10 1 J3KNG6;Q08AE8-3;Q08AE8-5;Q08AE8-2;Q08AE8;Q08AE8-4;K7EMJ7 J3KNG6 SPIRE1 Protein spire homolog 1 1 LRPVS(1)PEEIR;LRPVS(1)PEEIR 86.288 0.0081488 0.0 12334.3 16559.9 16180.900000000001 12829.2 18181.2 14145.0 18784.4 12385.5 11986.0 13400.5 True False 14422.253376470502 18203.85743143358 16566.714022404965 12110.421516827591 14618.724374836249 13403.21129915064 17005.005644721085 12060.393748521989 12161.272574715793 15829.904571700361 0.9110764572929667 1.1499663405411307 1.0465454132946463 0.7650343981528347 0.9234878396532232 0.8467019645280743 1.074232985277845 0.761874065247541 0.7682467395575396 1.0 13.950364937971504 -5.733524335165307 24.261270973645125 0.8760429717020822 1.0472733667777447 0.2979172309227507 0.11127892560493836 181.84664568379662 158042.87778593914 0.02978516228153168 0.051572383301063514 1.847037295512045e-06 5.733524335165307 0.1712303950756625 LRPVS(ph)PEEIR ddPTM_PC-9_Lapatinib_30min_R1 3 LRPVSPEEIR 10 1 J3KNG6;Q08AE8-3;Q08AE8-5;Q08AE8-2;Q08AE8;Q08AE8-4;K7EMJ7 J3KNG6 SPIRE1 Protein spire homolog 1 1 LRPVS(1)PEEIR;LRPVS(1)PEEIR;LRPVS(1)PEEIR 83.243 0.010639000000000001 2038000.0 14111.2 16912.8 18724.4 17272.3 19746.0 17852.8 17060.6 17312.1 16744.2 15103.199999999999 True False 13909.971700322852 16873.639450719344 17184.952110274207 18542.562560703715 18584.579102129668 17089.27736090945 17943.914389843085 18116.483366928245 14858.291871757207 17713.76799625101 0.7852632880405117 0.9525720024271814 0.9701466178122734 1.046788157360315 1.0491601282156886 0.9647454660423618 1.012992514841607 1.0227345966573835 0.8387990559039645 1.0 14.112583508143839 -4.655256319286836 2.058442783304599 0.993380388116949 0.6731271473018922 0.5293934271224991 0.057001479965629646 0.8598200773960059 3.017759033176571 0.015091548087301362 0.5825310147055145 2.2117889331866533e-05 4.655256319286836 -0.3202532408150568 LRRPS(ph)VNGEPGSVPPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LRRPSVNGEPGSVPPPR 17 2 Q8N3D4 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 LRRPS(1)VNGEPGSVPPPR;LRRPS(1)VNGEPGSVPPPR 88.385 0.0076884 59234000.0 23969.0 17621.2 15148.4 24020.5 19853.6 19453.0 19252.0 28679.0 24091.0 16557.3 True False 28026.47829067083 19370.516281546228 15509.595306626925 22674.709260511732 15963.42960026009 18432.850434950684 17428.311187590247 27926.20663791227 24443.285299305724 19559.007422485323 1.4329192522546506 0.9903629495675531 0.7929643346214422 1.159297543618934 0.8161676743324048 0.9424225901034224 0.8910631716185353 1.4277926294873169 1.2497201300310037 1.0 14.255545538030157 -7.7514684415961055 24.999266504713233 1.254067310355767 0.9914156734895877 0.20029037059425858 0.2001065523217027 266.7638861553049 668837.9542160394 0.09416894202687774 0.053543373575905814 1.7722768245650012e-08 7.7514684415961055 -0.2626516368661792 LRS(ph)AGAAQK ddPTM_PC-9_AZD4547_30min_R2 1 LRSAGAAQK 9 1 Q6PL18;E5RHW7;E5RIP2 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 LRS(1)AGAAQK 65.842 0.023615 3805200.0 29643.0 17601.0 27432.0 31106.0 30142.0 31268.0 24194.0 22583.0 28254.0 40600.0 True False 39068.8573872969 23290.179043685395 27068.2337562496 23934.99228290929 25957.30358879249 29312.807017061445 26347.21913001159 19093.31625571417 29747.44875831579 39178.60635767825 0.9971987525697212 0.594461651623322 0.690893226500507 0.6109199511691793 0.6625376960021795 0.7481840152621126 0.6724899525388055 0.48734036329427144 0.7592778693233397 1.0 15.257778459221667 -13.307488174725034 11.405860192620645 0.8693948716007759 0.6982367503649296 0.0 0.15859448701343287 0.0 0.0 0.0 0.033921484936990605 4.926197565634449e-14 13.307488174725034 -0.17115812123584628 LRS(ph)PPEALVQGR ddPTM_PC-9_AZD4547_30min_R2 4 LRSPPEALVQGR 12 1 Q9UHB6;Q9UHB6-4;F8VRN8 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 LRS(1)PPEALVQGR;LRS(1)PPEALVQGR;LRS(1)PPEALVQGR;LRS(1)PPEALVQGR 121.18 0.00021636 483180000.0 70410.0 61305.9 85080.0 122057.0 111848.0 91826.0 80930.0 100864.0 85322.0 89996.0 True False 92798.91538102 81121.83327278412 83951.78360971563 93918.64441185162 96319.83583701341 86084.10570387266 88132.61321781579 85277.78642414001 89831.94673168464 86845.26743265027 1.068554661921985 0.9340961882084736 0.9666823085647288 1.081448041883075 1.1090971181787286 0.9912354265087858 1.014823442004642 0.9819508759101252 1.0343908123876822 1.0 16.406159612049002 -5.730198984071808 24.997412566592967 1.0306643872354546 0.9842095558354796 0.12422791349627704 0.04878125757673323 398.8133863618926 319112.84885171853 0.013823066075590387 0.023939789112207916 1.861234165175548e-06 5.730198984071808 -0.04645483139997497 LRS(ph)PPEALVQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LRSPPEALVQGR 12 1 Q9UHB6;Q9UHB6-4;F8VRN8 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 LRS(1)PPEALVQGR;LRS(1)PPEALVQGR;LRS(1)PPEALVQGR 113.37 0.00039733 217440000.0 85800.0 110575.0 97091.0 98592.0 114332.0 113595.0 115324.0 85188.0 93703.0 83048.0 True False 100324.24537275448 121552.15523528325 99406.01765966792 93068.2098795769 91929.46533912912 107637.87822743127 104399.67584654373 82951.90526414689 95073.22910634037 98103.94499239382 1.0226321212723177 1.2390139381724905 1.013272378265472 0.9486693923143728 0.9370618617452803 1.0971819556876803 1.0641740844839422 0.845551167902354 0.9691070946607863 1.0 16.582023531351034 -5.458575274634864 8.602725993926974 0.9804035298043631 1.1304051728082647 0.3494394007816456 0.08102583564443823 0.40467960162345945 50.80804825612843 0.021593237666984202 0.04493180293094713 3.478762063442989e-06 5.458575274634864 0.15000164300390162 LRS(ph)PSNDSAHR ddPTM_PC-9_AZD4547_30min_R2 3 LRSPSNDSAHR 11 1 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 LRS(0.89)PS(0.023)NDS(0.087)AHR;LRS(0.996)PS(0.004)NDSAHR;LRS(0.906)PS(0.094)NDSAHR 109.99 0.00093989 43216000.0 24487.2 13949.5 62617.0 113537.0 85946.0 56564.0 41554.9 79107.0 50433.0 68198.0 True False 32273.620234598962 18458.40307765977 61786.657666778985 87362.79877916389 74013.88143594853 53027.04413819443 45253.20559749189 66882.83084801771 53098.7854189899 65810.40877785553 0.4904029747564595 0.28047847476478244 0.9388584391770183 1.3274921156326338 1.1246531181075625 0.8057546689489254 0.68762991201354 1.0162956299782633 0.8068447895260158 1.0 16.00602816266784 -5.270184454128321 23.18408657710372 0.9673004774197544 0.3854407129875933 0.6322313286989834 0.17631490939232858 140.24503631071624 371806.9177419968 0.05065904603982676 0.10844230961067476 5.368037559437237e-06 5.270184454128321 -0.5818597644321611 LRS(ph)PSNDSAHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LRSPSNDSAHR 11 1 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 LRS(0.945)PS(0.053)NDS(0.002)AHR;LRS(0.997)PS(0.003)NDSAHR;LRS(0.994)PS(0.006)NDSAHR 101.75 0.0016999000000000003 50389000.0 17587.5 21112.3 58033.0 49077.0 54058.0 49150.0 44353.0 35264.0 40596.0 26894.1 True False 20564.716381041064 23208.189617670098 59416.726811378074 46327.374799780744 43465.72295859996 46572.48747637002 40151.56275208755 34338.3573652965 41189.63969991346 31769.78743642155 0.647304185531479 0.7305113282270105 1.870227395455013 1.4582211131406586 1.3681464833714923 1.465936389079467 1.26382849845753 1.0808494527706625 1.296503471492944 1.0 14.955367816927062 -5.126159286872127 8.206456761283295 1.3583370639891017 0.6690762805853917 0.5828262630744452 0.22421396962924306 0.18646233790380742 11.387391521777458 0.058383623930941986 0.15614066308575253 7.478951435196354e-06 5.126159286872127 -0.68926078340371 LRS(ph)PSNDSAHR ddPTM_PC-9_Lapatinib_30min_R1 2 LRSPSNDSAHR 11 1 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 LRS(0.996)PS(0.004)NDSAHR;LRS(0.974)PS(0.006)NDS(0.02)AHR 101.45 0.0017587 12108900.0 6444.5 4587.5 11545.6 8030.1 10441.5 8609.7 5933.96 7368.6 6924.200000000001 3684.2999999999997 True False 6352.600248223438 4576.8779256051575 10596.36533530483 8620.660341628332 9827.351498778839 8241.48320119097 6241.191413710727 7710.972056396825 6144.323680941533 4321.126345978835 1.4701260133564613 1.0591863229975491 2.452222982363296 1.9950030735969033 2.2742569209817254 1.9072534661848872 1.4443436534825396 1.7844819704409989 1.421926412001198 1.0 12.077191699355584 -8.546099032063848 0.9590731977529516 1.0033657674749934 1.8460420447924686 0.307097492039181 0.3837428223004962 0.8340276213823774 1.6864158282108752 0.39450980229082316 0.1332986865912513 2.8438125596283864e-09 8.546099032063848 0.8426762773174752 LRS(ph)SLIFSTSQAEGAAGAAAATEK ddPTM_PC-9_AZD4547_30min_R2 2 LRSSLIFSTSQAEGAAGAAAATEK 24 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LRS(0.474)S(0.474)LIFS(0.048)T(0.004)SQAEGAAGAAAATEK;LRS(0.499)S(0.499)LIFS(0.002)TSQAEGAAGAAAATEK 96.303 2.6407e-06 12787800.0 52420.0 48128.0 64975.0 104823.0 95858.0 74078.0 59910.0 94008.0 72272.0 76495.0 True False 69088.46959626566 63684.43480566394 64113.389046089185 80657.67684920605 82549.77132952282 69445.89094952903 65241.87393895156 79481.22368893321 76092.15037378781 73816.93333326597 0.9359433733767776 0.8627347673486218 0.8685458220897964 1.0926717381370443 1.1183039934323762 0.9407853701534481 0.8838334375718366 1.076734295234053 1.0308224270202309 1.0 16.171664182741353 -5.745721958588403 24.999679410953792 1.018712956008017 0.8864406151538234 0.43590536228689225 0.06844669046894891 249.56558430256106 396948.6361874291 0.020311645289250058 0.035028827821981474 1.7958830083296962e-06 5.745721958588403 -0.1322723408541936 LRS(ph)YEDMIGEEVPSDQYYWAPLAQHER ddPTM_PC-9_AZD4547_30min_R2 8 LRSYEDMIGEEVPSDQYYWAPLAQHER 27 1 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 LRS(0.549)Y(0.451)EDMIGEEVPSDQYYWAPLAQHER;LRS(0.547)Y(0.453)EDMIGEEVPSDQYYWAPLAQHER;LRS(0.641)Y(0.359)EDMIGEEVPSDQYYWAPLAQHER;LRS(0.534)Y(0.465)EDMIGEEVPS(0.001)DQYYWAPLAQHER;LRS(0.55)Y(0.418)EDMIGEEVPS(0.026)DQY(0.005)Y(0.002)WAPLAQHER;LRS(0.568)Y(0.432)EDMIGEEVPSDQYYWAPLAQHER;LRS(0.548)Y(0.452)EDMIGEEVPSDQYYWAPLAQHER;LRS(0.55)Y(0.449)EDMIGEEVPS(0.001)DQYYWAPLAQHER 147.0 6.5662e-10 36136100.0 38441.8 39485.6 68866.2 89894.0 72781.9 57130.4 52480.3 69727.1 47046.6 52516.90000000001 True False 50665.49276088759 52248.548017007226 67952.98919162423 69170.32714845521 62677.38949204221 53558.02705665627 57150.94503218761 58952.378864358485 49533.38722846248 50678.299315900294 0.9997472970643139 1.030984636862395 1.3408695656506375 1.3648904576944445 1.2367697878207449 1.0568236854754212 1.127720262985552 1.1632667169212247 0.9774082377883072 1.0 15.62908049026169 -6.764614172277303 24.97761361871894 1.0791652182834375 1.2031405545581546 0.2203115467110418 0.11992545289831813 153.61262402844937 1208531.4812091305 0.04597499654505446 0.04224265531481691 1.719435257102321e-07 6.764614172277303 0.12397533627471713 LRS(ph)YEDMIGEEVPSDQYYWAPLAQHER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LRSYEDMIGEEVPSDQYYWAPLAQHER 27 1 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 LRS(0.538)Y(0.462)EDMIGEEVPSDQYYWAPLAQHER;LRS(0.525)Y(0.453)EDMIGEEVPS(0.021)DQY(0.001)YWAPLAQHER;LRS(0.593)Y(0.407)EDMIGEEVPSDQYYWAPLAQHER 85.84899999999999 1.2461e-06 10446900.0 9837.4 9146.8 15123.0 15444.0 20563.199999999997 22644.8 22102.2 22022.899999999998 23398.3 16375.400000000001 True False 11502.677522493434 10054.833854904711 15483.589674296883 14578.722750123557 16533.988574166313 21457.2668241079 20008.519609929193 21444.82221019134 23740.45587226536 19344.130392404924 0.5946339943515747 0.519787328297401 0.8004283139228733 0.7536509760008439 0.8547289662945016 1.1092391536262936 1.0343457784892274 1.1085958259778486 1.2272692227915587 1.0 14.239608254013492 -6.157096724459648 0.7531045627996963 1.1302081212318893 0.5363356084702738 0.8650584915936618 0.08161637760474512 0.25132513701748416 0.29845988740138335 0.044925232579177056 0.09068536932020548 6.964713813077642e-07 6.157096724459648 -0.5938725127616155 LRS(ph)YEDMIGEEVPSDQYYWAPLAQHER ddPTM_PC-9_Lapatinib_30min_R1 1 LRSYEDMIGEEVPSDQYYWAPLAQHER 27 1 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 LRS(0.776)Y(0.224)EDMIGEEVPSDQYYWAPLAQHER 130.21 1.0040999999999999e-10 3908900.0 4139.4 2996.0 3287.7 3319.1 3834.8 3987.5 3570.7 3574.5 5620.2 5044.2 True False 4080.371396927008 2989.0629460736895 3017.397996889004 3563.197686193023 3609.2446035068815 3816.963920316501 3755.573374430717 3740.5843193538053 4987.193892670288 5916.083249025984 0.6897082453325509 0.5052435573089349 0.5100330522539189 0.6022899841342941 0.6100733291914212 0.6451842814999131 0.6348073913681032 0.632273780117893 0.842989133645368 1.0 12.530426638335024 -8.434965888917956 1.3826829727082428 1.0037641566501674 0.5895548534386946 0.8566205870732126 0.05399331984243967 0.14921522274625312 0.615243355153972 0.05355673968308257 0.01626223406813178 3.6731114933046363e-09 8.434965888917956 -0.41420930321147276 LRT(ph)EVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LRTEVR 6 1 H0YBZ4;Q15390-2;Q15390 H0YBZ4 MTFR1 Mitochondrial fission regulator 1 1 LRT(1)EVR 65.252 0.041713 3808700.0 83010.0 61587.0 81296.0 99603.0 124660.0 101320.0 92214.0 104470.0 95622.0 59715.0 True False 97061.95347776664 67700.95034569644 83234.404956797 94022.56682728283 100233.76787929775 96006.60083633383 83478.82234845465 101727.77319511451 97020.29085094886 70540.85679632012 1.3759678842294703 0.9597409702745229 1.1799460445614982 1.3328809869543246 1.420932101359543 1.3610070134750927 1.183410949905126 1.4421113921091657 1.375377267263503 1.0 16.106171478538666 -5.706332779364283 5.232571784501516 1.3232331833078057 1.146405001130227 0.11570288475167989 0.15488159647704738 0.30547422612585023 17.31127099943579 0.040382186667082605 0.06998759556530426 1.96637896888863e-06 5.706332779364283 -0.17682818217757879 LRT(ph)STSDLSR ddPTM_PC-9_AZD4547_30min_R2 1 LRTSTSDLSR 10 1 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 LRT(0.447)S(0.447)T(0.081)S(0.025)DLSR 62.732 0.041971 5874000.0 4080.4 4362.3 6692.1 10730.0 8852.2 7094.7 3809.0 9711.4 6546.3 5990.6 True False 5377.882322407529 5772.328165574047 6603.358381459534 8256.364276847446 7623.224830094517 6651.067287448695 4147.993620989256 8210.726275771274 6892.324053463671 5780.870917396729 0.930289293646661 0.9985222379214568 1.142277431171771 1.4282215248918744 1.3186983309302893 1.150530323628786 0.7175378382012378 1.4203268665041857 1.1922639602143992 1.0 12.497071143055496 -5.238820191027019 3.5894981886409214 1.1853031204209328 0.9510291893638206 0.15192357600761808 0.19697103036871202 0.4339331203152873 12.051884978739881 0.05439960151029292 0.15445084312820556 5.770053088336504e-06 5.238820191027019 -0.23427393105711214 LRT(ph)STSDLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LRTSTSDLSR 10 1 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 LRT(0.848)S(0.126)T(0.02)S(0.006)DLSR 77.64399999999999 0.015486000000000002 21737000.0 26591.0 44287.0 34227.0 32058.0 47582.0 35119.0 33054.0 37245.0 32345.0 29944.0 True False 31092.331103810277 48683.52067741346 35043.10148662035 30261.894193438326 38258.64867024498 33277.29781653383 29922.885829763545 36267.3582143395 32817.98443427187 35372.61016342644 0.8789945373032787 1.3763055780302538 0.9906846377667998 0.8555177029239321 1.0815896393702538 0.9407645537829418 0.8459337801625494 1.0252949399769822 0.9277795526721992 1.0 15.11034505973876 -5.49875105561336 24.836193301456312 0.952708665593394 1.1416113486686714 0.2153563721602032 0.13029796456995693 852.8114777049518 877852.5894394347 0.031575415378546606 0.06514686846354668 3.1713848294869226e-06 5.49875105561336 0.18890268307527747 LRTS(ph)TSDLSR ddPTM_PC-9_AZD4547_30min_R2 1 LRTSTSDLSR 10 1 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 LRT(0.034)S(0.808)T(0.124)S(0.034)DLSR 71.806 0.015197 37792000.0 16424.0 18176.0 26048.0 32705.0 25676.0 17584.0 23854.0 23469.0 17816.0 26877.0 True False 21646.490359577798 24051.036548947537 25702.586500539153 25165.36753721302 22111.330600021094 16484.46970026893 25976.95978867886 19842.405313968746 18757.717387915123 25936.044410722123 0.8346103213267557 0.9273209194153249 0.990998707956929 0.9702854891322402 0.8525328785633993 0.6355814880334701 1.0015775488855896 0.7650513316427608 0.7232296911151403 1.0 14.662670845870476 -6.510398146842411 24.119552116790157 0.812836879029306 0.9319240448518106 0.16146460692978726 0.11262238693515805 619.053604477638 1196363.7673600046 0.03504980886762985 0.03780347812710167 3.087463649930493e-07 6.510398146842411 0.11908716582250456 LRTS(ph)TSDLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LRTSTSDLSR 10 1 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 LRT(0.09)S(0.303)T(0.303)S(0.303)DLSR;LRT(0.034)S(0.804)T(0.128)S(0.034)DLSR;LRT(0.009)S(0.741)T(0.125)S(0.125)DLSR 94.82 0.013459 49284900.0 64447.9 61301.4 80275.0 98515.6 101248.5 87226.7 98489.2 92923.7 94942.2 66736.6 True False 75357.65656595297 67386.99786516125 82189.0604446329 92996.0903238844 81409.58324343852 82652.37829817063 89159.58997594069 90484.55133579849 96330.55006200429 78835.41729336516 0.955885808094722 0.854780759444684 1.0425398033828888 1.1796232393598431 1.0326524046989476 1.0484168300980974 1.1309585594524965 1.1477652360116795 1.221919707782298 1.0 16.26655629443549 -5.442617378135744 4.573568635895175 1.110477927223075 0.908361800952002 0.5802233474385632 0.06825638974538847 0.1480305934245811 5.540811624854539 0.018334536638658618 0.039213377443944215 3.6089645978249943e-06 5.442617378135744 -0.2021161262710729 LRTS(ph)TSDLSR ddPTM_PC-9_Lapatinib_30min_R1 4 LRTSTSDLSR 10 1 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 LRT(0.127)S(0.434)T(0.434)S(0.005)DLSR;LRT(0.044)S(0.779)T(0.133)S(0.044)DLSR;LRT(0.121)S(0.72)T(0.121)S(0.035)DLS(0.003)R;LRT(0.012)S(0.777)T(0.156)S(0.055)DLSR 114.71 0.0057191 109017000.0 187136.6 146841.0 191135.2 163195.5 162807.7 169353.3 125424.0 144772.6 201606.0 136159.8 True False 184467.99776735032 146500.99868638444 175420.80165920831 175197.4414742286 153231.6711782537 162110.45414082412 131917.8410156547 151499.26351436044 178899.0092747028 159694.84000847113 1.1551281040612524 0.9173809164943162 1.0984750769023157 1.0970764081352604 0.9595280046000572 1.0151264382257112 0.8260620130785504 0.9486797663989898 1.1202554150479314 1.0 17.28495817219249 -6.27325712083168 24.12239843519428 0.969941150284796 1.0585741080068427 0.18696556893882976 0.08895730350960751 820.8181834121926 1675452.6700665867 0.027721798367352182 0.031701702450588766 5.330192319649053e-07 6.27325712083168 0.08863295772204671 LRVEFPR ddPTM_PC-9_Lapatinib_30min_R1 1 LRVEFPR 7 1 J3KTL2;Q07955;Q07955-3;Q07955-2;Q13242;S4R3G0 J3KTL2;Q13242 SRSF1;SRSF9 Serine/arginine-rich splicing factor 1;Serine/arginine-rich splicing factor 9 0 74.255 0.044655 5598000.0 18552.0 17387.0 17709.0 17044.0 19052.0 14110.0 18435.0 16840.0 22037.0 19068.0 False True 18287.44507797988 17346.741469754106 16253.034378716857 18297.472617117255 17931.398817673176 13506.548192016502 19389.474096852227 17622.44787744247 19554.961000102325 22363.878393487088 0.8177224341957445 0.7756589069454922 0.7267538345875705 0.8181708152395396 0.8018018387586673 0.6039448057430835 0.8669996212507988 0.7879871088269985 0.8743993620443407 1.0 14.448882784807669 -8.574641114431897 1.147794158853034 0.9993980949362873 0.766331599691852 0.5386469708966617 0.06608868214530794 0.43405866972964513 1.2408088959077619 0.062123712672734664 0.019609971731540072 2.662924697416129e-09 8.574641114431897 -0.23306649524443523 LRVQS(ph)PEPPAPER ddPTM_PC-9_AZD4547_30min_R2 3 LRVQSPEPPAPER 13 1 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 LRVQS(1)PEPPAPER;LRVQS(1)PEPPAPER;LRVQS(1)PEPPAPER 114.54 0.00014306 30162700.0 19015.7 32337.8 44179.0 50548.0 42779.0 34098.9 31655.7 58248.0 37155.5 35327.1 True False 25062.29704886893 42790.36144985455 43593.15759395422 38894.93955881497 36839.87426929052 31966.690392544344 34472.9959747833 49247.110005882256 39119.463875543384 34090.30898173238 0.7351736548442199 1.2552060315083733 1.2787551329415652 1.1409383112267244 1.0806553348938996 0.9377060914781971 1.0112256827374604 1.4446073232211476 1.1475244737883112 1.0 15.05707405513153 LRVQS(ph)PEPPAPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LRVQSPEPPAPER 13 1 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 LRVQS(1)PEPPAPER;LRVQS(1)PEPPAPER 97.223 0.018340000000000002 5211300.0 20028.0 15455.6 22697.2 17760.3 27518.0 20073.7 18973.4 23386.0 21935.0 19924.7 True False 23418.344828968897 16989.929825498028 23238.387327610355 16765.247970669483 22126.045439615857 19020.99983427077 17176.102196479576 22772.14227951519 22255.757878057 23536.89038616159 0.9949634146547076 0.7218425861169486 0.9873176509872885 0.7122966413832872 0.9400581417766539 0.8081356339856212 0.7297523978179458 0.9675085326013995 0.9455691687777997 1.0 14.522636108557792 -7.810824425149218 23.57032131425082 0.9674052314905822 0.8404904064533284 0.2572513887525073 0.10034630895579906 87.64145085140477 41827.16641100012 0.050678846103801745 0.02434544702324539 1.5458792751694538e-08 7.810824425149218 -0.12691482503725382 LRVQS(ph)PEPPAPER ddPTM_PC-9_Lapatinib_30min_R1 2 LRVQSPEPPAPER 13 1 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 LRVQS(1)PEPPAPER;LRVQS(1)PEPPAPER 109.1 0.00038879 13935900.0 23503.0 20772.4 17105.2 15115.5 16933.0 16974.7 15084.1 13558.7 21960.0 11885.0 True False 23167.842910077674 20724.302784052452 15698.876483981458 16227.144293829846 15937.034231558871 16248.73165095837 15865.080890931853 14188.686700467882 19486.633550948267 13939.306414232951 1.66205134040398 1.4867527958845623 1.126230819343484 1.1641285306176254 1.1433161563394652 1.1656771985704644 1.1381542538395282 1.0178904372157496 1.397962923826047 1.0 13.76687115756779 -5.111538473227351 2.8313702708584434 1.1444242096304467 1.650151118487434 0.7462013289980665 0.10249085516896905 0.12762178487549333 1.8751660835699757 0.025430962695598844 0.10220410713522364 7.735021528239772e-06 5.111538473227351 0.5057269088569873 LRVTS(ph)AEIK ddPTM_PC-9_AZD4547_30min_R2 1 LRVTSAEIK 9 1 Q8N4X5-2;Q8N4X5;Q8N4X5-4;Q8N4X5-3 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 LRVT(0.085)S(0.915)AEIK 59.975 0.033951999999999996 6465300.0 26604.0 20489.0 30483.0 58252.0 48904.0 35293.0 21886.0 34614.0 25920.0 37066.0 True False 35063.518602423734 27111.6685657673 30078.775502761622 44822.90138442846 42114.523744486374 33086.123130777465 23833.81160120003 29265.201650590734 27290.07828327124 35768.33062201236 0.9802950820647224 0.7579797014368452 0.8409331657276367 1.2531449079383028 1.1774249178564813 0.925011666896631 0.6663383833332257 0.818187517887136 0.7629676255138539 1.0 15.126395166052962 -7.009860628062183 24.17759874629136 0.7965726967411816 0.9991913835066069 0.24868306625687808 0.15485010171570718 461.7879740887175 1132274.096107849 0.06205364560357976 0.0516104009922627 9.775508820946892e-08 7.009860628062183 0.20261868676542527 LRWEPVPR ddPTM_PC-9_AZD4547_30min_R2 1 LRWEPVPR 8 1 Q02388-2;Q02388 Q02388-2 COL7A1 Collagen alpha-1(VII) chain 0 78.77 0.028073 1344400.0 7566.5 7085.6 9373.5 15980.0 10481.0 10676.0 6903.6 10237.0 7355.8 8561.3 False True 9972.489607022975 9375.881633539982 9249.201265463898 12296.057888538879 9025.894065229057 10008.428032306136 7518.007025954699 8655.106872857721 7744.612570836665 8261.57149285691 1.2070935433585914 1.1348787142550933 1.1195450252365313 1.4883437006107434 1.0925153977101079 1.211443614687543 0.9099972120866945 1.0476344458607019 0.937426078989062 1.0 13.012200517797003 -7.251130780548366 24.436448700828986 0.9777339722436528 1.2089428714022 0.5320890948560356 0.1080287846578558 423.2426354017981 1003294.6122993383 0.041734621938731106 0.03194662307843248 5.608790512166419e-08 7.251130780548366 0.23120889915854714 LS(ph)AEYEK ddPTM_PC-9_Lapatinib_30min_R1 2 LSAEYEK 7 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 LS(1)AEYEK;LS(1)AEYEK 114.51 0.008629799999999998 39179000.0 205792.0 282830.0 190861.0 202308.0 252580.0 171521.0 255340.0 307640.0 256570.0 266050.0 True False 202857.36834236945 282175.1245120233 175169.1453247661 217186.40519970434 237723.74099138597 164185.44666497954 268560.25581178453 321934.0774950355 227672.38479812382 312036.3880106586 0.6501080519347641 0.9043019832109602 0.5613740962761774 0.6960290964279642 0.7618462144974764 0.5261740392257432 0.8606696722903067 1.0317196643233761 0.7296340861064797 1.0 18.251354752695676 -7.502951352818057 23.643110477801287 0.9176450694359465 0.6920789433089785 0.4435096092542803 0.12305889732283479 347.29836956507353 412059.10534779145 0.04994175427650126 0.03310275873058814 3.140860495386731e-08 7.502951352818057 -0.22556612612696803 LS(ph)ASPAQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSASPAQEK 9 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 LS(0.975)AS(0.025)PAQEK 105.2 0.0026519 17964000.0 83274.0 77056.0 80532.0 96834.0 81836.0 74522.0 86685.0 75368.0 70287.0 64671.0 True False 97370.64346352873 84705.6104346369 82452.1882993108 91408.70492006384 65800.82326464159 70613.93513151664 78473.56925494786 73389.66985899692 71314.81440506004 76395.34036464567 1.2745625976501316 1.108779802934644 1.0792829497945156 1.1965219931445723 0.8613198521083227 0.9243225410668561 1.0272036079737652 0.9606563634470078 0.9334969130926628 1.0 16.22119702516876 -6.252972090022727 24.98670525939771 0.951659016363682 1.1546789207199173 0.7255275502896522 0.06424743779061462 357.2419955443989 1054208.9702376085 0.019494613688930306 0.024758931218576894 5.585060860316771e-07 6.252972090022727 0.2030199043562353 LS(ph)ASSSISSADLFEEPR ddPTM_PC-9_AZD4547_30min_R2 1 LSASSSISSADLFEEPR 17 0 H0Y6A0;Q9NP61-2;Q9NP61 H0Y6A0 ARFGAP3 ADP-ribosylation factor GTPase-activating protein 3 1 LS(0.959)AS(0.03)S(0.008)S(0.002)ISSADLFEEPR 79.471 0.006367800000000001 2074000.0 5841.0 5368.4 6477.8 9997.9 8243.3 7454.7 9615.5 8372.9 6890.5 8067.7 True False 7698.316499652576 7103.630315216223 6391.900139480673 7693.038621015205 7098.860084715455 6988.556430538825 10471.260872308276 7079.060695101146 7254.717762765445 7785.252278616765 0.9888332740092483 0.9124470294594424 0.8210267195883787 0.9881553411114451 0.9118343029439678 0.8976660203721116 1.3450124026255377 0.9092911111621561 0.9318539082787973 1.0 12.926528074796488 LS(ph)ASSSISSADLFEEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSASSSISSADLFEEPR 17 0 H0Y6A0;Q9NP61-2;Q9NP61 H0Y6A0 ARFGAP3 ADP-ribosylation factor GTPase-activating protein 3 1 LS(0.962)AS(0.026)S(0.008)S(0.003)ISSADLFEEPR 105.17 0.0051955 0.0 1206.3 3383.0 3028.2 3732.7 3703.6 2027.6 3017.3 3885.1 3321.9 2129.9 True False 1410.5027644889751 3718.841882531888 3100.403772512452 3523.568920576679 2977.9061665150552 1921.2690866141986 2731.4795006397285 3783.1202416037127 3370.4765030826293 2516.034009720876 0.5606056035170421 1.4780570803748592 1.232258292429205 1.4004456644715932 1.1835715077815734 0.7636101416718689 1.0856290058427127 1.503604572508702 1.339598944235473 1.0 11.296935708200447 -7.725302973437225 24.988506991295107 1.3162019244083711 1.1219412535563642 0.07132371638215873 0.28298759102907495 431.96987106184287 298709.28186116205 0.13393642035373018 0.07732481415319004 1.8823354724758324e-08 7.725302973437225 -0.19426067085200693 LS(ph)ASSSISSADLFEEPR ddPTM_PC-9_Lapatinib_30min_R1 1 LSASSSISSADLFEEPR 17 0 H0Y6A0;Q9NP61-2;Q9NP61 H0Y6A0 ARFGAP3 ADP-ribosylation factor GTPase-activating protein 3 1 LS(0.999)AS(0.001)SSISSADLFEEPR 129.05 3.754e-05 0.0 1601.4 1625.9 2422.1 2923.3 3010.4 2743.1 3761.5 1609.0 2686.6 2815.7 True False 1578.563742339206 1622.1353284449979 2222.9642875763793 3138.2892338429265 2833.3341906741175 2625.784007478419 3956.252064839146 1683.7600139432855 2384.0068168477983 3302.3899933155853 0.4780064576062789 0.4912004129519485 0.6731380279361048 0.9503084857316012 0.8579647456566637 0.7951162681552771 1.1979966245195304 0.5098610452888387 0.7219034764740992 1.0 11.689294788983126 -5.4755088778782985 3.2002278472503667 0.8521029169726495 0.48645485240500846 0.43970584748971286 0.17056883053255303 0.24091696723153413 4.892576593701381 0.04788465871536888 0.10628763130082154 3.3457317841498555e-06 5.4755088778782985 -0.36564806456764104 LS(ph)ASSTGSTR ddPTM_PC-9_Lapatinib_30min_R1 1 LSASSTGSTR 10 0 P56945-6;A0A2R8Y6M6;A0A2R8Y5C9;A0A2R8Y8C4;A0A2R8YFS8;A0A2R8Y5E4;A0A2R8Y4C2;A0A2R8YFK2;A0A2R8Y596;P56945;P56945-8;P56945-2;P56945-3;P56945-5;P56945-7;P56945-4 P56945-6 BCAR1 Breast cancer anti-estrogen resistance protein 1 1 LS(0.999)ASSTGSTR 73.95100000000001 0.026617000000000002 2804000.0 12194.0 12089.0 12866.0 12312.0 8608.8 10353.0 11848.0 10998.0 18037.0 7531.4 True False 12020.11132389427 12061.008663245944 11808.207144196229 13217.465551627987 8102.447309552008 9910.226324021747 12461.431467290764 11509.007230172941 16005.483121969677 8833.192455040307 1.3607890222108177 1.365418983525465 1.3367994871954079 1.4963407192702984 0.9172728150996723 1.1219303071299973 1.4107505899727282 1.3029272586046494 1.8119703836903032 1.0 13.108719229518984 -10.275958256887083 13.101260540862299 1.0000010206534016 1.3330599664969482 0.18112831361073822 0.21960061107495124 0.0 0.0 0.2171257009613953 0.05266071759412394 5.297143560364495e-11 10.275958256887083 0.33305894584354667 LS(ph)DEHEPEQR ddPTM_PC-9_AZD4547_30min_R2 1 LSDEHEPEQR 10 0 Q9UK59-2;Q9UK59 Q9UK59-2 DBR1 Lariat debranching enzyme 1 LS(1)DEHEPEQR 124.12 0.00053419 0.0 9112.0 7269.7 11715.0 15248.0 14745.0 9487.4 9947.7 13198.0 8356.5 13553.0 True False 12009.426458625958 9619.488358268269 11559.651445554975 11732.809179251615 12697.911267226635 8894.15137820356 10833.026028751603 11158.552359868732 8798.207529867133 13078.513595212147 0.9182562201122331 0.735518473734647 0.8838658431174315 0.8971057065343285 0.9708986556297311 0.6800582737062397 0.8283071275559492 0.8531972902451022 0.6727222834472588 1.0 13.674910963912101 -6.750874975829222 24.999347310084605 0.7990224424687961 0.8740791163325515 0.11152642193458506 0.10268370074388858 485.2824648815085 1148358.198513875 0.03301543144599607 0.032687491060941605 1.774700305938841e-07 6.750874975829222 0.07505667386375547 LS(ph)DEHEPEQR ddPTM_PC-9_Lapatinib_30min_R1 1 LSDEHEPEQR 10 0 Q9UK59-2;Q9UK59 Q9UK59-2 DBR1 Lariat debranching enzyme 1 LS(1)DEHEPEQR 99.539 0.0043347 4201200.0 10085.0 14821.0 19477.0 16612.0 17074.0 19908.0 12278.0 17200.0 17435.0 13302.0 True False 9941.186050637507 14786.682885099533 17875.676243394206 17833.70189600749 16069.74088877554 19056.581247814647 12913.694763284613 17999.174791687088 15471.286701310713 15601.232976199133 0.6372051533236855 0.9477893771381879 1.1457861228445796 1.1430956721955345 1.030030185004682 1.2214791790422532 0.8277355246848397 1.153702070800827 0.9916707689009796 1.0 13.929372430326456 -4.8135260673780005 3.0147125960982333 1.0680264967795274 0.5838263162775188 0.5939489928653174 0.10632806684725465 0.22466693418365707 3.1145186677635235 0.025933399347540256 0.25552707945460523 1.5362925786640823e-05 4.8135260673780005 -0.48420018050200864 LS(ph)DGEINAQESTYK ddPTM_PC-9_AZD4547_30min_R2 1 LSDGEINAQESTYK 14 0 A0A3B3IRW6;Q2KHR3-2;Q2KHR3 A0A3B3IRW6 QSER1 Glutamine and serine-rich protein 1 1 LS(1)DGEINAQESTYK 143.67 6.1148e-06 0.0 10199.0 11187.0 9749.9 10757.0 12897.0 12789.0 11760.0 14108.0 13941.0 9063.9 True False 13442.069847621397 14802.978976291597 9620.609955528507 8277.139843993287 11106.47416842469 11989.301808276798 12806.617217861298 11927.932769588437 14677.89279888442 8746.575619836442 1.536838007452425 1.692431371966851 1.0999287462524001 0.9463291925609703 1.2698082828251334 1.3707423715729556 1.4641864170038215 1.3637260212484719 1.6781302119650447 1.0 13.094502581235421 -6.9335389582531315 5.307024129447303 1.4083012125130054 1.2993278473515362 0.010244623119494034 0.24917418763606966 0.8778985538661142 47.234643926864514 0.09546004676394634 0.08346825873722032 1.1653625076623823e-07 6.9335389582531315 -0.10897336516146927 LS(ph)DGEINAQESTYK ddPTM_PC-9_Lapatinib_30min_R1 2 LSDGEINAQESTYK 14 0 A0A3B3IRW6;Q2KHR3-2;Q2KHR3 A0A3B3IRW6 QSER1 Glutamine and serine-rich protein 1 1 LS(1)DGEINAQESTYK;LS(1)DGEINAQESTYK 139.67 2.0327e-05 2857200.0 18581.7 25856.0 29984.0 23296.8 31517.0 29716.0 28437.0 30859.0 28537.0 20448.0 True False 18316.721550533563 25796.13202058792 27518.831261587096 25010.124387846565 29663.23202480607 28445.115951379346 29909.32871669037 32292.821796318138 25322.86255206789 23982.40955475268 0.7637565153207748 1.0756271992476172 1.1474589823328902 1.0428528597490412 1.2368745499522837 1.1860824862672015 1.2471360998321008 1.3465211542898763 1.0558931742973912 1.0 14.549688995684988 -4.268461209239799 1.1188788543992911 1.1832356444174397 2.8239988883355654e-14 0.5699441014790985 0.1013055920282412 3.143519820968777 1.4849970370162575 0.03049561198939075 5.787727864236339 5.389379806391619e-05 4.268461209239799 -1.1832356444174115 LS(ph)DTPAPK ddPTM_PC-9_Lapatinib_30min_R1 1 LSDTPAPK 8 0 I3NI13;I3L270;J3KNE2;H3BNM4;Q8NBZ0-2;Q8NBZ0 I3NI13 INO80E INO80 complex subunit E 1 LS(0.925)DT(0.075)PAPK 78.098 0.022608 7697700.0 69534.0 61393.0 75740.0 74660.0 76625.0 61943.0 52096.0 53041.0 70744.0 49213.0 True False 68542.43240902625 61250.84828047467 69512.94956485489 80150.74545845902 72118.06815054623 59293.842286185594 54793.27597231432 55505.47849569037 62776.06575265407 57719.401477799445 1.1875111427721519 1.061183011470303 1.2043255436664841 1.3886274529247729 1.2494597363121467 1.0272774971339875 0.9493042992379157 0.961643348242954 1.0876077046086412 1.0 15.816768719408229 -6.816953599860561 5.712147972537139 0.9965695153015228 1.218154192481922 0.6254414691931813 0.0824784935780571 0.14623406024261132 9.919277972795207 0.03268588120048555 0.02914054783576409 1.5242155927027853e-07 6.816953599860561 0.2215846771803991 LS(ph)EGSQPAEEEEDQETPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSEGSQPAEEEEDQETPSR 19 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 LS(0.998)EGS(0.002)QPAEEEEDQETPSR 167.95 6.8814e-08 7256000.0 1632.0 2311.5 4267.6 4985.4 6123.7 2343.0 5065.2 8239.3 9024.7 5722.9 True False 1908.2653665307187 2540.9704438286903 4369.355768963127 4706.084200884874 4923.804944348268 2220.1289553842307 4585.387587127678 8023.027105259966 9156.669164444987 6760.416467548523 0.2822703861057687 0.37586004590484984 0.6463145857858004 0.6961234153953543 0.7283286418793292 0.3284012110853429 0.6782699866404002 1.1867652153934969 1.3544534139869935 1.0 12.722896409447605 -7.702820105315995 3.8646943916474945 1.212557010537734 0.5268235882597005 0.7663895127607727 0.165283582873696 0.1074472575182727 3.223397445188655 0.09262006112954671 0.04808972741315224 1.982347989532289e-08 7.702820105315995 -0.6857334222780334 LS(ph)EGSQPAEEEEDQETPSR ddPTM_PC-9_Lapatinib_30min_R1 1 LSEGSQPAEEEEDQETPSR 19 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 LS(0.89)EGS(0.11)QPAEEEEDQETPSR 214.24 1.176e-27 6832200.0 5736.4 6637.0 7733.8 7092.9 10959.0 15151.0 16492.0 19207.0 14832.0 15848.0 True False 5654.597884073078 6621.632434276063 7097.95681733132 7614.535527220781 10314.413166222976 14503.027048706028 17345.87506402426 20099.427338600814 13161.463972115882 18587.30568386738 0.30421826488714365 0.3562448773854957 0.38187120489936865 0.4096632215948179 0.5549170676832007 0.7802651602859122 0.93321083534336 1.081352385356521 0.7080888535415443 1.0 14.18203003962748 -6.689705982010048 1.4776375593509388 0.942555511130104 0.35061987356903923 0.890755906247024 0.0907374551903527 0.11608563778927988 0.5273874729054863 0.038587196070431616 0.037133783688341825 2.0431206722011264e-07 6.689705982010048 -0.5919356375610648 down LS(ph)FADR ddPTM_PC-9_AZD4547_30min_R2 2 LSFADR 6 0 A0A087X0I9;Q04759-3;Q04759-2;Q04759 A0A087X0I9 PRKCQ Protein kinase C;Protein kinase C theta type 1 LS(1)FADR;LS(1)FADR 118.74 0.019835 7630000.0 58469.0 72897.0 67281.0 52354.0 57579.0 73473.0 73867.0 83626.0 69815.0 54863.0 True False 77060.92576924965 96459.52967146959 66388.80997937558 40284.594161236826 49585.14973588625 68878.72169516933 80441.01990066007 70703.52323430694 73505.2783698526 52942.263068997534 1.4555653895795733 1.8219759428447126 1.253985117577118 0.7609156055292825 0.9365891607478869 1.3010158180318518 1.5194103016681495 1.3354835841105217 1.3884045393763413 1.0 15.692132245116381 -5.365359202172359 6.319214329384802 1.187434857082264 1.635304898148568 0.3815565416839095 0.23109474645259664 0.25331763057901824 12.945906515589774 0.06765303103811941 0.14289520673796471 4.31162317732006e-06 5.365359202172359 0.4478700410663041 LS(ph)FADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSFADR 6 0 A0A087X0I9;Q04759-3;Q04759-2;Q04759 A0A087X0I9 PRKCQ Protein kinase C;Protein kinase C theta type 1 LS(1)FADR;LS(1)FADR 89.75200000000001 0.037759 5536900.0 41621.0 67698.0 51978.0 41370.0 50547.0 34629.0 47416.0 23287.0 33815.0 33230.0 True False 48666.613247778805 74418.61003950443 53217.35264766269 39052.17302334964 40642.678204675605 32812.99427912955 42924.413217887966 22675.74092461602 34309.48040330508 39254.33595146473 1.2397767550558416 1.8958061125150072 1.3557063533939857 0.9948499210796726 1.0353678700596913 0.8359075114581112 1.0934948249019174 0.5776620690425894 0.8740303350367812 1.0 15.260564399418191 -5.706193515953199 2.722338922006878 0.8962551351834386 1.5817055931755295 0.6499253752027714 0.1994381023013708 0.1490118365311716 2.238294269560749 0.055985969466511055 0.10480850705534499 1.9670096205895164e-06 5.706193515953199 0.6854504579920909 LS(ph)FADR ddPTM_PC-9_Lapatinib_30min_R1 3 LSFADR 6 0 A0A087X0I9;Q04759-3;Q04759-2;Q04759 A0A087X0I9 PRKCQ Protein kinase C;Protein kinase C theta type 1 LS(1)FADR;LS(1)FADR;LS(1)FADR 105.14 0.034339999999999996 10390700.0 50788.0 81785.0 61260.0 64294.0 74368.0 74865.0 75800.0 82218.0 65980.0 52567.0 True False 50063.75380662146 81595.63185735537 56223.439270438415 69022.39523849668 69993.82045311351 71663.1984688388 79724.5531077515 86038.14843156573 58548.63759979813 61653.13590887537 0.8120228285000254 1.3234627996531343 0.9119315415445832 1.1195277291411947 1.1352840276699931 1.1623609636784498 1.2931143230992512 1.395519419462003 0.9496457355605439 1.0 15.911886656904626 -6.306080323697429 1.9031671894357147 1.1914458430250754 1.0454184251183225 0.08905068559569296 0.17336218359848451 0.757728900658666 5.401836376757056 0.05886012423180153 0.07467039632454783 4.942192716173371e-07 6.306080323697429 -0.1460274179067529 LS(ph)FCDSPGQMMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSFCDSPGQMMK 12 0 A0A1B0GUL6;E9PEZ5;Q9UPP5-2;Q9UPP5 A0A1B0GUL6 KIAA1107 Uncharacterized protein KIAA1107 1 LS(0.991)FCDS(0.009)PGQMMK 54.471000000000004 0.043074 4656100.0 21925.0 31864.0 24639.0 34773.0 26025.0 37068.0 26899.0 23648.0 30733.0 29213.0 True False 25636.469461511035 35027.24733816021 25226.487203927863 32824.78154558708 20925.588072025683 35124.08882551541 24350.931988104592 23027.265057127133 31182.41198387623 34509.08565001924 0.7428904295381336 1.0150152250742315 0.7310100145731853 0.9511924447516847 0.6063790934435846 1.0178214856728849 0.7056382842206953 0.6672812282151641 0.9036000634765832 1.0 15.074688628296553 LS(ph)GFSFK ddPTM_PC-9_Lapatinib_30min_R1 2 LSGFSFK 7 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 LS(0.999)GFS(0.001)FK;LS(0.999)GFS(0.001)FK 102.62 0.010818000000000001 22943000.0 41789.0 120949.0 121253.0 95233.0 108929.0 88864.0 93652.0 87003.0 89417.0 80308.0 True False 41193.081196835956 120668.95002158453 111284.0463901155 102236.7525079752 102522.01038265393 85063.4938721017 98500.84231724465 91045.47700006673 79345.9158572468 94189.13079631623 0.43734431827294273 1.2811345534394074 1.181495629583492 1.085441086923946 1.088469651602981 0.903113694254715 1.0457771664785025 0.9666240279566054 0.8424105327910092 1.0 16.523272965385488 -6.75882278835312 24.989002362034082 0.9553860927583898 1.042762608105528 0.012533968757907021 0.2173230464680322 292.4786059757248 2793244.0994003317 0.07229703260558869 0.06913566962060695 1.7425177538225374e-07 6.75882278835312 0.08737651534713808 LS(ph)GFSFKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSGFSFKK 8 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 LS(0.556)GFS(0.444)FKK 90.15 0.014236000000000002 396390000.0 1194700.0 808790.0 755330.0 893800.0 1278200.0 960850.0 606700.0 1029300.0 730510.0 548640.0 True False 1396939.1135994196 889081.3260931025 773339.9318049768 843723.283738696 1027745.8856354745 910461.3345202467 549228.9838723774 1002281.9656335 741192.3267608569 648104.0889681499 2.1554240088555745 1.371818726693445 1.193234150144332 1.3018329896390448 1.5857728768101964 1.4048072678723527 0.8474394672417636 1.5464830151422726 1.143631616243794 1.0 19.305866010661795 -4.763061858255633 4.134834906335473 1.2769277412997202 2.2444426124761225 0.6043707912080012 0.21704080419575417 0.16057904489580493 5.365826711289784 0.053391276212561616 0.47517979155202583 1.725592091678704e-05 4.763061858255633 0.9675148711764023 LS(ph)GPAELR ddPTM_PC-9_AZD4547_30min_R2 2 LSGPAELR 8 0 Q96PC5;Q96PC5-11;Q96PC5-13;G3V599;Q96PC5-10;Q96PC5-9;Q96PC5-6;Q96PC5-12;Q96PC5-7;Q96PC5-14;Q96PC5-5;Q96PC5-8;Q96RT6 Q96PC5 MIA2;CTAGE1 Melanoma inhibitory activity protein 2;cTAGE family member 2 1 LS(1)GPAELR;LS(1)GPAELR 89.029 0.010532 6943400.0 24276.0 34897.0 39567.0 31652.0 37952.0 31925.0 51050.0 51193.0 42415.0 30464.0 True False 31995.263027831876 46176.772801970874 39042.31572738148 24355.120418525195 32683.019899205527 29928.724703200947 55593.351103045876 43282.29814811037 44656.97030806132 29397.46463251992 1.088368110236222 1.5707739894987212 1.3280844527045463 0.828476901765984 1.1117632186229787 1.01807162887419 1.8910933918276636 1.4723139797651406 1.5190755688047024 1.0 14.843404115569708 -7.232828805298658 24.995551939484752 1.509980407969862 1.1670778826048775 0.23543558621710114 0.2723657219170556 991.6167848806172 866324.5417036469 0.1055038994521569 0.08170734170164655 5.850206482026291e-08 7.232828805298658 -0.34290252536498445 LS(ph)GPAELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSGPAELR 8 0 Q96PC5;Q96PC5-11;Q96PC5-13;G3V599;Q96PC5-10;Q96PC5-9;Q96PC5-6;Q96PC5-12;Q96PC5-7;Q96PC5-14;Q96PC5-5;Q96PC5-8;Q96RT6 Q96PC5 MIA2;CTAGE1 Melanoma inhibitory activity protein 2;cTAGE family member 2 1 LS(1)GPAELR;LS(1)GPAELR 96.14299999999999 0.0062104 6509600.0 32497.0 55217.0 41962.0 34637.0 62654.0 25928.0 35754.0 27379.0 25281.0 26662.0 True False 37998.10025499311 60698.578843559924 42962.53322177118 32696.40118466911 50377.39846550226 24568.29003636464 32367.12228345634 26660.330260448412 25650.68679804691 31495.609543724135 1.2064570524422402 1.9272076242656755 1.364080068433918 1.0381256834949635 1.5995054293381834 0.780054439088008 1.0276709278644796 0.8464776724970796 0.8144210310467894 1.0 14.94286311194109 -6.462948716041508 0.8287858444060483 0.8615006653425509 1.5460895088391222 0.4724578884967968 0.25634313375773166 0.5229454857643876 0.7922291030837048 0.1449254196843903 0.1915591455118626 3.443905959594383e-07 6.462948716041508 0.6845888434965713 LS(ph)GPAELR ddPTM_PC-9_Lapatinib_30min_R1 2 LSGPAELR 8 0 Q96PC5;Q96PC5-11;Q96PC5-13;G3V599;Q96PC5-10;Q96PC5-9;Q96PC5-6;Q96PC5-12;Q96PC5-7;Q96PC5-14;Q96PC5-5;Q96PC5-8;Q96RT6 Q96PC5 MIA2;CTAGE1 Melanoma inhibitory activity protein 2;cTAGE family member 2 1 LS(1)GPAELR;LS(1)GPAELR 104.22 0.0038615999999999998 5957600.0 30126.0 57819.0 25489.3 19581.9 26622.4 23673.0 33980.0 25783.0 31444.0 15788.2 True False 29696.39771556822 57685.12365788875 23393.668145543357 21022.01824930345 25056.522773652236 22660.560974458305 35739.31813458309 26980.972305469077 27902.445600000792 18517.169333545884 1.6037223174154343 3.115223640223769 1.2633501224813644 1.1352716968040983 1.3531508149174611 1.2237594508252518 1.9300637959732534 1.4570786614015612 1.5068418448521963 1.0 14.17657595435827 -5.288474673044778 24.99963653101163 1.382423985587624 2.35947315377403 0.48295129170883455 0.41362100032897225 510.8420368790135 472376.647647153 0.10262070268029637 0.21370613164508281 5.146658201468658e-06 5.288474673044778 0.977049168186406 LS(ph)HSDEKPYQCPVCQQR ddPTM_PC-9_AZD4547_30min_R2 1 LSHSDEKPYQCPVCQQR 17 1 I3L2Z5;A0A087WWR2;P56270-3;P56270;P56270-2 I3L2Z5 MAZ Myc-associated zinc finger protein 1 LS(0.499)HS(0.499)DEKPY(0.002)QCPVCQQR 53.328 0.026133 2686500.0 11059.0 13268.0 21837.0 30895.0 22013.0 18171.0 15160.0 25552.0 15877.0 20458.0 True False 14575.53195851016 17556.621530118613 21547.427111957677 23772.635072991798 18956.874922038656 17034.764497474207 16509.21063118854 21603.525526546902 16716.225806462076 19741.771646930578 0.7383092165781556 0.8893133728881061 1.0914636992727975 1.2041794170326112 0.9602418294097755 0.86287921885282 0.8362578053502796 1.0943053092150312 0.8467439551739061 1.0 14.268963844093046 -6.522598688511664 24.9612370355444 0.9263468301934131 0.9946872061685591 0.029174031890196295 0.1349820811117523 37.4770200097556 3340791.387808628 0.047560837951868856 0.04804754424593257 3.0019351875123865e-07 6.522598688511664 0.06834037597514597 LS(ph)LDGNPKPIHGTTER ddPTM_PC-9_AZD4547_30min_R2 1 LSLDGNPKPIHGTTER 16 1 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;F8VT91 B8ZZZ7 SPATS2L SPATS2-like protein 1 LS(1)LDGNPKPIHGTTER 62.68 0.015368999999999999 7201100.0 17903.0 20876.0 37032.0 53533.0 39184.0 46588.0 29894.0 55458.0 37561.0 38714.0 True False 23595.78159446671 27623.75874756983 36540.93148372102 41191.79392660525 33743.977965073514 43674.84499523023 32554.508087648443 46888.24039806033 39546.397777698716 37358.63464362448 0.63160181895174 0.739420993595761 0.9781120705372726 1.102604372979539 0.9032444115521809 1.1690696250507555 0.8714051891402328 1.2550844227938653 1.0585611105690553 1.0 15.189154108984956 -5.21733002487715 2.208234268760824 1.0545166571610973 0.6324195554132221 0.6479110021514853 0.10765121526315884 0.2011369888802096 1.7867660788679944 0.028465138675559064 0.11377845702337712 6.062754395041355e-06 5.21733002487715 -0.4220971017478752 LS(ph)LDGNPKPIHGTTER ddPTM_PC-9_Lapatinib_30min_R1 1 LSLDGNPKPIHGTTER 16 1 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;F8VT91 B8ZZZ7 SPATS2L SPATS2-like protein 1 LS(1)LDGNPKPIHGTTER 53.453 0.031675 8629700.0 13398.0 16369.0 24686.0 14354.0 24147.0 29156.0 29269.0 32016.0 17801.0 21807.0 True False 13206.942063107708 16331.098586208363 22656.4123707157 15409.641043540312 22726.72093482858 27909.06584595559 30784.405605683114 33503.580240154275 15796.063927159848 25576.31089399901 0.5163740039696837 0.6385244007195793 0.8858358214605373 0.6024966269531815 0.8885847935231727 1.091207639820484 1.2036296295141644 1.309945768919131 0.6176052516966429 1.0 14.642520565631653 -6.5128199418078 3.2011322104303392 1.0727183909092914 0.6759982948623106 0.4679778205128797 0.19088648074739645 0.2215033305920837 4.688262690882474 0.06482346732352481 0.06942888310017853 3.070294666595081e-07 6.5128199418078 -0.3967200960469809 LS(ph)LDGQGR ddPTM_PC-9_AZD4547_30min_R2 1 LSLDGQGR 8 0 O95801 O95801 TTC4 Tetratricopeptide repeat protein 4 1 LS(1)LDGQGR 72.096 0.033615 4217900.0 28335.0 26003.0 42483.0 39700.0 43882.0 42074.0 34303.0 48347.0 39424.0 37326.0 True False 37344.94059538705 34407.96123362034 41919.64766210092 30547.778358885713 37789.741758456374 39443.1061288168 37355.900546283694 40876.08205353641 41507.87215430885 36019.22810115019 1.036805688631471 0.955266479808922 1.1638130485301075 0.8480964187544663 1.0491546807259216 1.0950569517495372 1.0371099691914503 1.134840589552532 1.15238094602542 1.0 15.136479643898161 -6.51912835427844 24.62129318415773 1.0874626641567926 1.0017672294950914 0.17850391137492405 0.08364533145046785 219.36354640312751 1440133.1734729165 0.026472423786400596 0.027058336329210644 3.0260189661674917e-07 6.51912835427844 -0.08569543466170115 LS(ph)LDGQGR ddPTM_PC-9_Lapatinib_30min_R1 1 LSLDGQGR 8 0 O95801 O95801 TTC4 Tetratricopeptide repeat protein 4 1 LS(1)LDGQGR 97.59700000000001 0.0057644 4970500.0 34640.0 38362.0 39885.0 30920.0 39467.0 33991.0 28785.0 32897.0 40725.0 23086.0 True False 34146.02724780202 38273.175145954236 36605.809260552334 33193.9599460963 37145.62865510746 32537.284166891062 30275.34645391329 34425.51471640292 36138.1216467381 27076.384339838623 1.2610999614731253 1.4135260700093293 1.3519459910565927 1.225937685382041 1.3718828994628183 1.2016849723549532 1.1181458378609253 1.2714221472233724 1.3346730934664184 1.0 14.724747480233065 -6.776412412533976 23.852271767674345 1.1979590515027145 1.3258104054668798 0.33710398079625015 0.0971190828799732 180.98066917383318 288302.2082477868 0.033770909409198906 0.0299191367308806 1.6733530801925297e-07 6.776412412533976 0.12785135396416525 LS(ph)LDLSHR ddPTM_PC-9_AZD4547_30min_R2 3 LSLDLSHR 8 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;A0A0J9YYG8 Q8TDM6-4 DLG5 Disks large homolog 5 1 LS(1)LDLSHR;LS(1)LDLSHR;LS(1)LDLSHR 90.149 0.0054927 11470700.0 99078.0 141806.0 136501.0 122553.0 157909.0 181814.0 145960.0 219229.0 171380.0 140870.0 True False 130582.74304957653 187642.0163325297 134690.90755183093 94300.29927497523 135986.06105774798 170445.14183830153 158950.157238013 185352.19543125224 180438.79692079563 135938.18417749126 0.9606038497548102 1.380348115342853 0.99082467789895 0.6936998595762436 1.0003521959672068 1.253843008641011 1.1692826279809325 1.3635035406184497 1.3273591817675083 1.0 17.05259123139443 -6.7608277862672885 24.943918747045466 1.242171979720058 1.0079087914497282 0.2632087659365321 0.1805822762044233 22.910576245170283 934424.5223124668 0.06541841429065788 0.06170931197634567 1.7344916511286375e-07 6.7608277862672885 -0.23426318827032988 LS(ph)LDLSHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LSLDLSHR 8 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;A0A0J9YYG8 Q8TDM6-4 DLG5 Disks large homolog 5 1 LS(1)LDLSHR;LS(1)LDLSHR;LS(1)LDLSHR;LS(1)LDLSHR 88.681 0.010936 8304800.0 122993.0 210034.0 180838.0 155543.0 184317.0 112373.0 148917.0 92976.0 108148.0 118582.0 True False 143813.28567752033 230884.7874536509 185149.86375193414 146828.42998721026 148201.4069806553 106479.9620586395 134810.5036942848 90535.47851621518 109729.45990408536 140079.97790540423 1.0266512590017483 1.6482354645256083 1.3217439531362971 1.0481757077829013 1.0579770870661862 0.7601369135747954 0.9623823883333427 0.6463127698189218 0.783334360447897 1.0 17.095891235766906 -6.150572654939885 1.352613940829919 0.8170533459162607 1.3690341286914027 0.5791322359072553 0.17821072053173778 0.27712316546641336 1.0244926176347044 0.06494711400737938 0.10165592896128396 7.070129116406719e-07 6.150572654939885 0.5519807827751421 LS(ph)LDLSHR ddPTM_PC-9_Lapatinib_30min_R1 3 LSLDLSHR 8 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;A0A0J9YYG8 Q8TDM6-4 DLG5 Disks large homolog 5 1 LS(1)LDLSHR;LS(1)LDLSHR;LS(1)LDLSHR 94.69200000000001 0.005534600000000001 8307300.0 90076.0 151312.0 134093.0 124332.0 142009.0 122740.0 137500.0 136424.0 122851.0 124661.0 True False 88791.49972208447 150961.64636058125 123068.39115394893 133475.79003939315 133656.30982043614 117490.69632091453 144619.07720733288 142762.75708029736 109014.22670161875 146208.48774965908 0.6072937425774825 1.0325094574472353 0.8417321938564124 0.9129141002260615 0.9141487739705303 0.8035832811709558 0.9891291499776155 0.9764327589841326 0.7456080585983145 1.0 17.157667540028818 -4.746316494430982 24.99526844071935 0.9089410424645048 0.607292933990535 0.5218546087624207 0.08768354565697417 658.6957085434458 1088639.2210602888 0.020599758425687734 0.4758536795161909 1.7934261815461074e-05 4.746316494430982 -0.30164810847396983 LS(ph)LGLSR ddPTM_PC-9_AZD4547_30min_R2 1 LSLGLSR 7 0 Q9NR12-2;Q9NR12;D6RAN1;H0Y8W6;D6RF83;H7BYK4;D6RH06;Q9NR12-3;Q9NR12-5;Q9NR12-6;Q9NR12-4 Q9NR12-2 PDLIM7 PDZ and LIM domain protein 7 1 LS(1)LGLSR 125.71 0.0045832 7178300.0 15471.0 14463.0 18238.0 23287.0 18860.0 18750.0 18694.0 21810.0 14835.0 18678.0 True False 20390.456183209215 19137.881910619963 17996.152203502483 17918.54193056352 16241.614547297018 17577.559535944176 20357.729784923387 18439.76564394128 15619.14781374725 18024.088905140747 1.131289148124072 1.0617946910571188 0.9984500352952489 0.9941441159587754 0.9011059939159899 0.9752259672293775 1.1294734447918224 1.0230622885288796 0.8665707263179572 1.0 14.137638714452102 -4.961963024927766 1.842096195455632 0.9875655587364291 1.1501695581114084 0.3341701717088642 0.06625393888570781 0.7456093253155995 3.4914908398767524 0.019529295816585763 0.1873528885125009 1.091533263724908e-05 4.961963024927766 0.16260399937497927 LS(ph)LGLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSLGLSR 7 0 Q9NR12-2;Q9NR12;D6RAN1;H0Y8W6;D6RF83;H7BYK4;D6RH06;Q9NR12-3;Q9NR12-5;Q9NR12-6;Q9NR12-4 Q9NR12-2 PDLIM7 PDZ and LIM domain protein 7 1 LS(0.999)LGLS(0.001)R 112.11 0.0092188 5347500.0 14190.0 14480.0 14882.0 14017.0 14131.0 11090.0 15631.0 12925.0 12338.0 12073.0 True False 16592.08673472482 15917.478705013807 15236.843320299296 13231.672933727139 11362.13199023227 10508.420877170774 14150.318521360025 12585.732445169495 12518.419908797228 14261.739330184588 1.163398541411293 1.116096594987183 1.0683720244452182 0.9277741394222975 0.7966862755782266 0.7368260374055488 0.9921874319642946 0.8824822943252182 0.8777624957919634 1.0 13.799862319957464 -5.719396704739096 2.496335572815142 0.8724916794488389 1.1347580834385025 0.6681972243924992 0.07516133788728081 0.1666917017321325 2.111644153384108 0.022823169177034603 0.043299439998608504 1.908109506480516e-06 5.719396704739096 0.2622664039896636 LS(ph)LHEEEGSSGSEQK ddPTM_PC-9_AZD4547_30min_R2 1 LSLHEEEGSSGSEQK 15 0 Q12955;A0A087WTF3;A0A087WZ65;Q12955-7;H0Y951;A0A087WX55;A0A087WY90;Q12955-6;Q12955-5;Q12955-4;H0Y3A4 Q12955;Q12955-6 ANK3 Ankyrin-3 1 LS(1)LHEEEGSSGSEQK 75.564 0.027696 0.0 17135.0 25040.0 29103.0 23963.0 28138.0 29519.0 22924.0 32104.0 32417.0 25870.0 True False 22583.57356985906 33133.6903161117 28717.075204437595 18438.70057465941 24231.524397234527 27673.172263548597 24964.191590327584 27143.0644765287 34130.49643938284 24964.299174215175 0.9046347911574827 1.3272429594312196 1.1503257112900866 0.7386027721420738 0.9706470919985806 1.10850987926516 0.9999956904903743 1.0872752440238298 1.367172224671748 1.0 14.60757878583387 -8.013818093109457 23.67736746027757 1.1981320215293816 1.0350884078263962 0.11645709661715087 0.16797665882617902 667.6238012774345 1143964.9658084789 0.10716322697689841 0.04426170763649247 9.68683510291893e-09 8.013818093109457 -0.16304361370298537 LS(ph)LITAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSLITAPR 8 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 LS(1)LITAPR 94.40899999999999 0.0067423000000000005 1283000.0 10271.0 10239.0 8687.0 12029.0 10729.0 8483.4 10259.0 10647.0 8647.3 5068.1 True False 12009.677438503075 11255.460252806388 8894.131025630959 11355.054128544181 8626.72946877093 8038.515569827817 9287.193251271985 10367.527531428987 8773.750403415648 5986.906410942472 2.0059905089801604 1.8800127278145524 1.4855971373420593 1.8966480096949845 1.4409327416582904 1.342682684188206 1.5512507819226082 1.7317002838861661 1.4654898208162344 1.0 12.54759500245174 -1.5228787452803407 0.04825074197057564 6.658171686407413e-16 4.46832310967556 0.6229006283663114 0.17688019475444247 398.65783459826986 1.4599177782374824 32.740688276173785 134.59704276036916 0.02999999999999978 1.5228787452803407 4.468323109675559 LS(ph)LITAPR ddPTM_PC-9_Lapatinib_30min_R1 1 LSLITAPR 8 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 LS(0.999)LIT(0.001)APR 95.775 0.0063234 2042000.0 8678.8 10585.0 9144.7 6736.9 8148.3 8286.6 7591.2 8838.2 8505.0 7479.4 True False 8555.038720502998 10560.491082840465 8392.858065562827 7232.35409963959 7669.033014174173 7932.201435008078 7984.235191973129 9248.8550374354 7547.077338379558 8772.204324325949 0.9752438958562861 1.2038583111379964 0.9567558797380987 0.8244625674739193 0.874242405971712 0.9042426671494094 0.9101743298240643 1.0543364809444378 0.8603398939820603 1.0 13.098723700670257 -5.464530582905626 8.817915713576866 0.9156870297408607 1.087973170744874 0.4094957657465539 0.08107906156029193 0.3642637718719894 52.19048835835965 0.02072092041605577 0.04305291638270535 3.431384752225474e-06 5.464530582905626 0.1722861410040134 LS(ph)LQGHPTDLQTSNVK ddPTM_PC-9_AZD4547_30min_R2 1 LSLQGHPTDLQTSNVK 16 0 Q9P270;D6RIF6 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 LS(1)LQGHPTDLQTSNVK 129.98 8.7471e-06 15871000.0 50333.0 30704.0 69084.0 86456.0 80458.0 74301.0 63039.0 101180.0 77800.0 75175.0 True False 66337.8470085625 40628.467550554895 68167.9010213163 66524.90493188474 69287.79550617292 69654.94672427652 68649.34887727539 85544.95588509757 81912.34916815204 72543.14613148924 0.914460573412694 0.5600593538762865 0.9396876845919735 0.9170391481409417 0.9551253178430422 0.960186460593015 0.9463243950413168 1.1792286445647353 1.129153524988846 1.0 16.146551694610494 -6.176966059964093 0.5924628022139526 1.0930419807837395 0.7242671269719353 0.4910513254053711 0.11093289485031535 0.8473264163635779 0.5975581944959404 0.07796743042557415 0.17349416565672 6.653251492112335e-07 6.176966059964093 -0.3687748538118042 LS(ph)LQGHPTDLQTSNVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LSLQGHPTDLQTSNVK 16 0 Q9P270;D6RIF6 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 LS(0.991)LQGHPT(0.009)DLQTSNVK;LS(1)LQGHPTDLQTSNVK;LS(0.998)LQGHPT(0.002)DLQTSNVK 142.23 1.4637e-05 56100000.0 105058.0 174376.0 210965.0 192886.0 235395.0 144731.0 125459.0 141342.0 120326.0 89120.0 True False 122842.24440991685 191686.89686916312 215995.20568921807 182079.2227648494 189271.0395471467 137141.05157563582 113574.6152754977 137631.9222642277 122085.5401155725 105276.75052646811 1.166850646468543 1.8207904015898575 2.0516895193769655 1.729529282147363 1.7978427202648244 1.3026717759602255 1.078819537148835 1.3073344454113354 1.159662883828072 1.0 16.68382733906619 -6.8610491264869555 4.17844885124809 1.1655444269789133 1.739272846216106 0.6031711525511946 0.22224876552615375 0.1579906139743906 5.0197176296191035 0.08237581385958867 0.07286686120671823 1.377053690639015e-07 6.8610491264869555 0.5737284192371928 LS(ph)LQGHPTDLQTSNVK ddPTM_PC-9_Lapatinib_30min_R1 3 LSLQGHPTDLQTSNVK 16 0 Q9P270;D6RIF6 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 LS(0.988)LQGHPT(0.012)DLQTSNVK;LS(1)LQGHPTDLQTSNVK;LS(0.997)LQGHPT(0.003)DLQTSNVK 127.88 2.298e-05 45510700.0 210065.0 213628.0 408524.0 272949.0 277483.0 249896.0 204288.0 234691.0 321500.0 229743.0 True False 207069.43457879714 213133.35749126528 374936.7336682434 293022.57999117137 261161.99549256795 239208.53061602835 214865.033051139 245595.6006416183 285289.28445491206 269453.7714366956 0.7684785166476885 0.7909830185521749 1.3914696078259552 1.0874688390101563 0.9692274637689542 0.8877535071808303 0.7974096332202147 0.9114572764453497 1.0587689418254693 1.0 18.039678254131402 -6.52289594414683 7.201094505884146 0.9181643764946098 1.0222600056799083 0.03911077043058475 0.1733452859140348 0.41742870595200376 140.20489621868296 0.06076580212097616 0.06358051139192365 2.999881196791622e-07 6.52289594414683 0.10409562918529847 LS(ph)LQGHPTDLQTSNVKNEEK ddPTM_PC-9_AZD4547_30min_R2 1 LSLQGHPTDLQTSNVKNEEK 20 1 Q9P270;D6RIF6 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 LS(0.959)LQGHPT(0.041)DLQTSNVKNEEK 55.02 0.009836 7281800.0 23731.0 22150.0 31286.0 35471.0 44310.0 33859.0 23315.0 44589.0 35901.0 34042.0 True False 31276.964364536074 29309.55433314196 30871.127198090737 27293.708971487038 38158.32134627414 31741.791377468453 25389.98983286022 37698.79460328741 37798.65356665586 32850.19994157838 0.9521087975159912 0.8922184457101269 0.9397546210675346 0.8308536636010392 1.1615856650533591 0.9662586965655872 0.7729021399569688 1.1475971126608633 1.150636940836827 1.0 15.003614531036042 -7.7933236089098985 24.999986234738778 1.11183793872092 0.9360659435809472 0.3556786450355678 0.10341580223291144 220.52434274501275 172907.19498026874 0.056877031827793606 0.02732651786068122 1.609445930465756e-08 7.7933236089098985 -0.17577199513997288 LS(ph)LQGHPTDLQTSNVKNEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSLQGHPTDLQTSNVKNEEK 20 1 Q9P270;D6RIF6 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 LS(0.995)LQGHPT(0.005)DLQTSNVKNEEK 83.31 0.0028899 0.0 6406.5 1974.4 6146.6 6569.3 8372.9 8659.8 6814.4 10297.0 6718.0 6247.1 True False 7490.993915857264 2170.4053836449775 6293.15825511031 6201.243418957957 6732.2903503655625 8205.664843293367 6168.890700016359 10026.714660573334 6816.238040792649 7379.649777983607 1.0150879975640361 0.2941068274161396 0.8527719396502084 0.8403167637383959 0.91227775746901 1.1119314723815332 0.8359327184361217 1.3586979006086388 0.9236533231059506 1.0 12.849336635425344 -6.109521187041725 1.2098785534563936 1.0597117642523064 0.6606632198955518 0.3048831507865474 0.21324466018899987 0.5077828873483102 1.5172833023408894 0.07924140926285973 0.1351795640385415 7.771034069052951e-07 6.109521187041725 -0.39904854435675463 LS(ph)LVLRGT(ph)QT(ph)VR ddPTM_PC-9_AZD4547_30min_R2 1 LSLVLRGTQTVR 12 1 O75161 O75161 NPHP4 Nephrocystin-4 3 LS(1)LVLRGT(1)QT(1)VR 69.65 0.02504 134060000.0 2565.4 3361.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 3381.1438363651264 4447.37752206276 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LS(ph)MT(ph)GS(ph)T(ph)EDTILEK ddPTM_PC-9_Lapatinib_30min_R1 1 LSMTGSTEDTILEK 14 0 Q8IYT3 Q8IYT3 CCDC170 Coiled-coil domain-containing protein 170 4 LS(0.994)MT(0.994)GS(0.994)T(0.986)EDT(0.031)ILEK 44.309 0.036895 1789900.0 2216.4 2829.8 1807.4 2440.1 2299.8 2784.8 2724.0 2688.5 2768.8 2395.7 True False 2184.7937295620186 2823.247771962393 1658.8025487657599 2619.553093934981 2164.5302855807663 2665.7005956858648 2865.035391365637 2813.4175248517854 2456.9485872434243 2809.7935529304054 0.7775637919317743 1.0047883300956242 0.5903645650534547 0.9322937947533484 0.7703520720671176 0.9487175998769509 1.0196604616654554 1.001289764480241 0.8744231705852588 1.0 11.456248418273764 -6.8600246113228005 5.811195835410851 0.9749463853786633 0.8200299000868206 0.33550741002505013 0.10834443709635722 0.24971349411506702 12.310214312571413 0.03682904910821968 0.03254532095827915 1.3803060409055157e-07 6.8600246113228005 -0.15491648529184265 LS(ph)NGLAR ddPTM_PC-9_AZD4547_30min_R2 1 LSNGLAR 7 0 Q16643-3;Q16643;Q16643-2;D6R9W4;D6RCR4 Q16643-3 DBN1 Drebrin 1 LS(1)NGLAR 90.149 0.016122 6773500.0 17901.0 17068.0 23040.0 30934.0 23287.0 27399.0 19512.0 33473.0 22672.0 24447.0 True False 23593.145636069286 22584.89721706848 22734.474545931418 23802.644225535798 20054.002012879406 25685.736198684514 21248.530200247427 28300.516983019126 23870.395634194632 23591.11797108766 1.0000859503557276 0.9573474747889283 0.9636878834565572 1.0089663514339327 0.850065776342469 1.0887884258034712 0.90070043421803 1.1996259362402035 1.0118382546960785 1.0 14.525956168331419 -7.743503891229002 24.9916441316169 1.0792991723445418 0.9683762719503419 0.2662697358596302 0.07822472334034755 270.12496196130354 376398.1130332607 0.03403138700847904 0.01959793393870287 1.8050785637611524e-08 7.743503891229002 -0.11092290039419983 LS(ph)NGLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSNGLAR 7 0 Q16643-3;Q16643;Q16643-2;D6R9W4;D6RCR4 Q16643-3 DBN1 Drebrin 1 LS(1)NGLAR 72.096 0.039726 4039300.0 13448.0 20873.0 24028.0 18171.0 21067.0 18227.0 21935.0 17275.0 15032.0 17440.0 True False 15724.48078989284 22945.133495148704 24600.91864669746 17152.937781176843 16939.072580724885 17271.14403320032 19857.158004352383 16821.549554375484 15251.814562249941 20601.73394503596 0.763260064994757 1.1137476853339032 1.194118840303979 0.8325968011692475 0.8222158691068039 0.8383344857903013 0.9638585789589335 0.8165113479891666 0.7403170336506992 1.0 14.330478146503086 -5.798130768371734 24.994162877797628 0.8534341750977564 1.0327130195092644 0.26724535516306314 0.1243760740278559 200.75461739588312 136753.145653437 0.035006930039120206 0.05192544480899672 1.5917293767304357e-06 5.798130768371734 0.179278844411508 LS(ph)NGLAR ddPTM_PC-9_Lapatinib_30min_R1 1 LSNGLAR 7 0 Q16643-3;Q16643;Q16643-2;D6R9W4;D6RCR4 Q16643-3 DBN1 Drebrin 1 LS(1)NGLAR 94.40899999999999 0.013456999999999998 5993200.0 24227.0 31932.0 41995.0 25280.0 32428.0 37293.0 30598.0 27612.0 36826.0 21547.0 True False 23881.51853731232 31858.06341589622 38542.333205387884 27139.175531607845 30520.64879590098 35698.06532422904 32182.214722836172 28894.954322561836 32678.26808502829 25271.37024042721 0.9450029147651238 1.2606385452313986 1.5251382429485678 1.0739099333914495 1.2077164200252337 1.4125892258553514 1.2734653648243228 1.1433869255074223 1.293094429551433 1.0 14.625216270404161 -10.652763541534679 4.65797447904996 0.999978601407126 1.2441667842112631 0.17253140046187965 0.15517936225398055 17677179.42413624 40427618.73075314 2347.0259739192466 0.03736444248113314 2.2245207363124747e-11 10.652763541534679 0.24418818280413712 LS(ph)NGSFSAPSLTNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSNGSFSAPSLTNSR 15 0 O94806;O94806-2 O94806 PRKD3 Serine/threonine-protein kinase D3 1 LS(1)NGSFSAPSLTNSR;LS(0.869)NGS(0.024)FS(0.014)APS(0.076)LT(0.013)NS(0.004)R 71.781 0.020978999999999998 9851000.0 22749.0 23813.0 31504.0 31569.0 36137.0 37476.0 34374.0 37060.0 35280.0 36066.0 True False 26599.95638676919 26176.99726536561 32255.17483958531 29800.29127807893 29056.21426162505 35510.69258727246 31117.845873791128 36087.21426831577 35795.903256797385 42604.48030170106 0.6243464583631393 0.6144188845866627 0.757084105032434 0.6994637903584309 0.6819990305213258 0.8334966730213731 0.7303890495420194 0.8470286226417113 0.8401910551029105 1.0 15.378717532281572 -6.131834247655033 0.06720462172747213 1.4319322193683133 4.851859920145182e-08 0.8437044936898248 0.044580065359723114 27.625424206382306 0.5087767874453121 3.9719493204492085 6.8935828000051975 7.381859115798171e-07 6.131834247655033 -1.4319321708497141 LS(ph)NGSFSAPSLTNSR ddPTM_PC-9_Lapatinib_30min_R1 1 LSNGSFSAPSLTNSR 15 0 O94806;O94806-2 O94806 PRKD3 Serine/threonine-protein kinase D3 1 LS(1)NGSFSAPSLTNSR 120.99 0.0012344 0.0 37427.0 28456.0 28811.0 30179.0 36649.0 30409.0 22534.0 23669.0 20185.0 24203.0 True False 36893.284116728784 28390.111880331413 26442.270793676165 32398.464334192773 34493.37787470629 29108.47795684125 23700.700260291196 24768.748147932663 17911.552742526917 28386.45630152967 1.2996791048814609 1.00012877897695 0.9315101016061403 1.1413352899723135 1.2151350456818921 1.0254354276434523 0.8349298696721799 0.8725551328010585 0.6309893898789231 1.0 14.792915137195374 -7.1866701643129485 3.3206503342838602 0.8203313655556395 1.103342327193147 0.5175410440191611 0.12823279575076774 0.2130882700974669 4.584778527440162 0.05410056127424178 0.03960945250222983 6.506236349636101e-08 7.1866701643129485 0.2830109616375076 LS(ph)PANQR ddPTM_PC-9_AZD4547_30min_R2 3 LSPANQR 7 0 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 LS(1)PANQR;LS(1)PANQR;LS(1)PANQR 91.265 0.015373 57194000.0 107633.0 109228.0 139461.0 155081.0 147484.0 137627.0 109891.0 147118.0 119132.0 138616.0 True False 141858.0550945221 144533.81493004184 137611.65601780152 119329.47142756563 127008.39235914918 129021.16193351385 119671.08611292456 124384.29353532146 125429.07430720172 133763.096031427 1.0605171329257603 1.0805208552894463 1.0287714631356193 0.8920956150680733 0.949502487063466 0.964549758202374 0.894649493495638 0.9298849774387545 0.9376956576852314 1.0 17.02932061944353 -5.60227844134713 4.950919516620467 0.935506073449135 1.067300745500979 0.7684786595346289 0.03022779783686079 0.08442884348099648 3.679346119033409 0.008027413705201299 0.014349529795073425 2.4987428168136787e-06 5.60227844134713 0.13179467205184414 LS(ph)PANQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSPANQR 7 0 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 LS(1)PANQR 95.775 0.013018 18603000.0 38729.0 55303.0 48212.0 52601.0 51923.0 39011.0 52316.0 43020.0 45477.0 39853.0 True False 45285.05476738249 60793.116355205704 49361.55692502818 49653.936504742924 41749.060882374215 36965.194485059415 47360.24974496005 41890.77058345778 46142.015090968634 47078.033423825575 0.9619147503401091 1.2913265897899444 1.0485050741318125 1.0547156049983542 0.8868055406334276 0.7851898602534195 1.0059946497465981 0.889815643026784 0.9801177265747206 1.0 15.522766435929382 -6.009037322065222 2.480168812278994 0.9171447044459453 1.121614860365925 0.39589923481440314 0.09901252757692364 0.25927417332649233 3.200027295431596 0.0297961534592934 0.045040310661174046 9.794058143683065e-07 6.009037322065222 0.20447015591997975 LS(ph)PANQR ddPTM_PC-9_Lapatinib_30min_R1 4 LSPANQR 7 0 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 LS(1)PANQR;LS(1)PANQR;LS(1)PANQR;LS(1)PANQR 106.88 0.0099897 86044000.0 116198.0 151865.0 164674.0 130976.0 166618.0 167031.0 154881.0 158101.0 174439.0 119208.0 True False 114540.99521189657 151513.3659230575 151135.13938002245 140608.4119631278 156817.8568235916 159887.47349827865 162899.98034144688 165446.9496360771 154791.84289589553 139812.94396532443 0.8192445703761473 1.083686256979432 1.0809810243142157 1.0056895161151935 1.1216261697664032 1.143581337776086 1.165128032650885 1.1833450104384489 1.107135280223311 1.0 17.093138406896387 -4.210755513089149 1.4560766458612375 1.1127090971423386 4.264799537936794e-22 0.6645814746924699 0.05893894345992862 3.3371217280052785 2.0235541175173113 0.017415142702946054 8.136448440610609 6.155232852069003e-05 4.210755513089149 -1.1127090971423386 LS(ph)PCLHR ddPTM_PC-9_Lapatinib_30min_R1 1 LSPCLHR 7 0 Q9C073;D6RFX7;D6RJ87;K7ENS5 Q9C073 FAM117A Protein FAM117A 1 LS(1)PCLHR 67.89699999999999 0.028626 1869500.0 7101.8 11809.0 11029.0 8149.0 12540.0 10731.0 10461.0 13620.0 11646.0 7991.5 True False 7000.527029689388 11781.6569860428 10122.238193171159 8748.304644267095 11802.421854588576 10272.060145182782 11002.619393933885 14252.83492225454 10334.304842183223 9372.820126995592 0.7468965513940115 1.2570023564315802 1.0799565185313964 0.9333695222711287 1.2592177908754747 1.0959412435108191 1.1738856870030128 1.520655974310606 1.1025822220164412 1.0 13.194267481008131 -6.270752552237055 24.569775511786773 1.212366587894449 1.0277595496541494 0.20365038779379263 0.17677542365393997 864.4602138584604 2280593.7850346984 0.05381433499099381 0.06185556475245266 5.361020251095182e-07 6.270752552237055 -0.18460703824029956 LS(ph)PDFAEELR ddPTM_PC-9_AZD4547_30min_R2 1 LSPDFAEELR 10 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 LS(1)PDFAEELR 95.094 0.006049499999999999 3708600.0 10853.0 18162.0 13224.0 11297.0 12266.0 11153.0 13777.0 17750.0 13985.0 9881.5 True False 14304.028243576335 24032.511322732476 13048.641119591897 8692.651186910129 10563.07762657186 10455.60114690055 15003.12631041454 15007.145354422639 14724.218549056635 9535.551692694517 1.500073483376436 2.5203063333131035 1.3684201543984988 0.9116044322395986 1.1077573660121378 1.0964862321401825 1.5733883884147892 1.5738098683813 1.5441391356870644 1.0 13.219100694756424 -5.412189294004552 7.777616111679085 1.2716645862844218 2.0057392799857103 0.4588867683952046 0.32227207363957416 0.23670380157019505 14.919447817484722 0.08574648016736892 0.17924756882089277 3.870888894340547e-06 5.412189294004552 0.7340746937012885 LS(ph)PDFAEELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSPDFAEELR 10 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 LS(1)PDFAEELR 136.81 0.00011605 1819400.0 18433.0 29935.0 23271.0 16029.0 28695.0 12377.0 17696.0 10519.0 12906.0 11836.0 True False 21553.342831654867 32906.74896647712 23825.868895758947 15130.947096719163 23072.42073878106 11727.92833153675 16019.706772054697 10242.887395801778 13094.725834246803 13981.773106275554 1.5415314400990316 2.3535462002102805 1.7040663379857728 1.082190862468496 1.6501784547215457 0.8388012194442498 1.1457564537980123 0.7325885864364641 0.9365568826438322 1.0 13.77125970803272 -6.039345992319544 0.8161135905330598 0.9048384837878266 2.0179552833244654 0.6194596836422339 0.29469493615408615 0.45387192432036383 0.6129878155484412 0.14387163078986134 0.32710697788684606 9.133852787112641e-07 6.039345992319544 1.113116799536639 LS(ph)PDFAEELR ddPTM_PC-9_Lapatinib_30min_R1 2 LSPDFAEELR 10 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 LS(1)PDFAEELR;LS(1)PDFAEELR 139.76 0.00012173 8009400.0 11685.3 19111.0 10498.8 9449.900000000001 11194.5 9714.2 9878.2 11818.099999999999 13268.099999999999 8516.1 True False 11518.665479178426 19066.749653676343 9635.629190539981 10144.87716994228 10536.061519233794 9298.746310906221 10389.644861596189 12367.212070095182 11773.70685871297 9988.096538010033 1.1532393019374374 1.9089472734987285 0.9647112594347956 1.015696747757254 1.0548618026606433 0.930982822955258 1.0402026874748407 1.238195087825928 1.1787738348250578 1.0 13.285994050084726 -5.285743042200929 24.9799569724251 1.0553646863238868 1.5310933898480235 0.5020709850025503 0.19046311886550707 503.45510319541955 517463.94966506417 0.04726449093156477 0.09846312688365116 5.179131735515239e-06 5.285743042200929 0.47572870352413665 LS(ph)PENNQVLTK ddPTM_PC-9_AZD4547_30min_R2 3 LSPENNQVLTK 11 0 Q16514-2;Q16514 Q16514-2 TAF12 Transcription initiation factor TFIID subunit 12 1 LS(1)PENNQVLTK;LS(1)PENNQVLTK;LS(1)PENNQVLTK 149.35 0.00010242 47388400.0 122945.0 160334.0 148227.0 111831.0 132094.0 159001.0 140973.0 168273.0 142114.0 118470.0 True False 162038.95258513704 212158.8299977418 146261.41313019872 86050.09072172671 113755.02820841214 149058.6423346482 153519.3238991122 142270.27437886002 149625.8559085189 114322.40135946144 1.4173858374059296 1.8557940305212397 1.2793766697596924 0.7526966692307423 0.9950370780852886 1.3038445708113353 1.3428630091175633 1.244465412614302 1.3088060968738189 1.0 16.80274860033063 -5.4502789176647095 6.61514242752758 1.1451518905417124 1.6268653541661795 0.49680115332100483 0.1988369063578422 0.2089799965474936 15.71039924277594 0.055789232817148655 0.11661316519855043 3.5458559000047535e-06 5.4502789176647095 0.4817134636244671 LS(ph)PENNQVLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSPENNQVLTK 11 0 Q16514-2;Q16514 Q16514-2 TAF12 Transcription initiation factor TFIID subunit 12 1 LS(0.972)PENNQVLT(0.028)K;LS(1)PENNQVLTK 154.1 0.00049426 25970000.0 98249.0 161467.0 108710.0 92362.0 115784.0 83618.0 104737.0 63810.0 66456.0 82327.0 True False 114880.61519379681 177496.3766617726 111302.05868497105 87187.2565816441 93096.95636239831 79232.9248789238 94815.553129786 62135.05511228357 67427.79327760011 97252.23339982671 1.1812645445528813 1.8251136293399395 1.1444678933735353 0.89650647120048 0.9572731967980099 0.8147157356600613 0.974944737155568 0.6389062023576548 0.6933289953392501 1.0 16.569443761554254 -5.5515516300994925 3.4379049406267606 0.8472819034697192 1.5074895631369098 0.6634140862139293 0.18390895874238594 0.12403610435078076 3.061858766224569 0.04938211794127204 0.09889629799185978 2.8083314908989747e-06 5.5515516300994925 0.6602076596671906 LS(ph)PENNQVLTK ddPTM_PC-9_Lapatinib_30min_R1 4 LSPENNQVLTK 11 0 Q16514-2;Q16514 Q16514-2 TAF12 Transcription initiation factor TFIID subunit 12 1 LS(1)PENNQVLTK;LS(1)PENNQVLTK;LS(1)PENNQVLTK;LS(0.999)PENNQVLT(0.001)K 165.78 0.0012050999999999997 49961000.0 114337.0 213084.0 174905.0 169291.0 214702.0 197599.0 211556.0 224941.0 195312.0 183217.0 True False 112706.53341316218 212590.61708984242 160524.98605282424 181741.2248782212 202073.65048037292 189148.1513957669 222509.33452854186 235392.5800474936 173313.90583346126 214885.81432869367 0.5244949917483338 0.9893189913628245 0.7470245839833894 0.8457572010790166 0.9403768746282944 0.8802263285115791 1.035477075225576 1.0954309886991067 0.8065395399640333 1.0 17.71321072093844 -3.8392702222197954 0.4809363181501346 0.976728580789291 6.395396467234412e-17 0.45517514760346 0.1168933138308815 10.854854249832721 0.9695111691817625 0.07027171840012575 7.285154392222695 0.00014478706940935826 3.8392702222197954 -0.9767285807892909 LS(ph)PEPGREGVR ddPTM_PC-9_AZD4547_30min_R2 2 LSPEPGREGVR 11 1 Q9NWK9-2;Q9NWK9 Q9NWK9-2 ZNHIT6 Box C/D snoRNA protein 1 1 LS(1)PEPGREGVR;LS(1)PEPGREGVR 104.07 0.013169 22699000.0 76340.0 79334.0 124503.0 131660.0 119972.0 107963.0 105759.0 153534.0 81430.0 112969.0 True False 100614.53202935745 104977.16403907389 122852.00887118491 101307.82112672269 103315.95866746135 101212.05654288751 115171.34611766918 129808.84816033371 85734.2235573601 109013.9896950876 0.9229506443235088 0.9629696549286498 1.12693801240375 0.9293102785255444 0.947731194468126 0.9284318171087755 1.0564822592018117 1.1907540355454322 0.7864515719235572 1.0 16.734153761444922 -7.27096929601405 24.19883773621239 1.0243181303744904 0.9737247239060227 0.020857934500969955 0.10806251017972103 1661.7671146299717 4219617.54243199 0.04417389243981308 0.030267685551333176 5.358345388940127e-08 7.27096929601405 -0.05059340646846766 LS(ph)PEPGREGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSPEPGREGVR 11 1 Q9NWK9-2;Q9NWK9 Q9NWK9-2 ZNHIT6 Box C/D snoRNA protein 1 1 LS(1)PEPGREGVR;LS(1)PEPGREGVR 115.29 0.0066331 15157800.0 43842.0 47437.0 62156.0 48322.0 65999.0 44854.0 55683.0 45590.0 44395.0 38741.0 True False 51263.584681029315 52146.23185978867 63638.0347679427 45614.67500203775 53066.96972778572 42501.77727904581 50408.30312999103 44393.310806597874 45044.19288791153 45764.43662641272 1.1201620397844643 1.1394487882692024 1.3905564988691312 0.9967275545070617 1.1595678574825585 0.9287075382572528 1.101473258405592 0.9700394909040898 0.9842619336848669 1.0 15.48193930029898 -6.21711067804944 1.6470811862091896 1.007667122395302 1.1976751424813827 0.38747458521586786 0.10079274278387637 0.38183576972890754 2.05372759911457 0.03493663871610863 0.04873050454039656 6.065817251892767e-07 6.21711067804944 0.19000802008608075 LS(ph)PEVAPPAHR ddPTM_PC-9_AZD4547_30min_R2 4 LSPEVAPPAHR 11 0 Q8TAD8 Q8TAD8 SNIP1 Smad nuclear-interacting protein 1 1 LS(1)PEVAPPAHR;LS(1)PEVAPPAHR;LS(1)PEVAPPAHR;LS(1)PEVAPPAHR 108.59 0.0012273 83719500.0 181472.0 190194.0 230438.0 229415.0 194330.0 234880.0 209679.0 245877.0 218016.0 199829.0 True False 239176.3211479115 251670.4910536165 227382.24155448537 176526.91617641735 167350.63387997 220192.9164694705 228340.02479795378 207882.35934137384 229539.88067151446 192833.0475332143 1.240328482112045 1.305121161922558 1.1791663538134987 0.915439124333767 0.8678524558978662 1.1418837138460078 1.1841332578567667 1.0780432192545595 1.190355510156928 1.0 17.556992794814782 -5.529033302605467 24.44554451823297 1.057678433254769 1.265079586266034 0.4358770706740597 0.10144355695535853 115.65518744272677 459374.152365577 0.030479275928146934 0.05299430135234302 2.9577856486908925e-06 5.529033302605467 0.20740115301126494 LS(ph)PEVAPPAHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LSPEVAPPAHR 11 0 Q8TAD8 Q8TAD8 SNIP1 Smad nuclear-interacting protein 1 1 LS(1)PEVAPPAHR;LS(1)PEVAPPAHR;LS(1)PEVAPPAHR;LS(1)PEVAPPAHR;LS(1)PEVAPPAHR;LS(1)PEVAPPAHR 90.73100000000001 0.0048611 80277900.0 294740.0 460620.0 383983.0 372180.0 399679.0 293193.0 367628.0 249102.0 280954.0 261287.0 True False 344633.6606196467 506347.309468471 393138.61098363594 351327.96122383984 321364.76906970865 277817.44294322206 332803.61444376863 242563.33644538594 285062.4207372517 308656.26475324575 1.1165613660722649 1.640489331630021 1.2737101296094844 1.1382498958986231 1.0411736477360103 0.9000868430949306 1.0782337909448474 0.7858688260849085 0.9235594844159212 1.0 18.235641548275332 -6.000775436572959 1.5367745776920259 0.9353597089803972 1.3901708157805166 0.6125374511460893 0.14011804126825275 0.23879129525919038 1.1399413942030021 0.04652014947523645 0.08040619189640404 9.982160843789e-07 6.000775436572959 0.4548111068001194 LS(ph)PEVAPPAHR ddPTM_PC-9_Lapatinib_30min_R1 4 LSPEVAPPAHR 11 0 Q8TAD8 Q8TAD8 SNIP1 Smad nuclear-interacting protein 1 1 LS(1)PEVAPPAHR;LS(1)PEVAPPAHR;LS(1)PEVAPPAHR;LS(1)PEVAPPAHR 107.39 0.0013125 81763200.0 356059.0 445744.0 433315.0 378968.0 479664.0 438276.0 432605.0 435492.0 435840.0 367029.0 True False 350981.5333667761 444711.9071544306 397689.51334427006 406838.57092018897 451451.1065757075 419531.95715125615 455003.1701474779 455726.5481617094 386751.1096013341 430469.47361459816 0.8153459301530215 1.0330858154011258 0.9238506740209035 0.9451043473629304 1.048741279573042 0.9745916560087268 1.0569928834369446 1.058673323186034 0.8984402688391201 1.0 18.715551408165 -4.753854857855256 24.99711042256859 0.9945748427020912 0.8153456107076644 0.49083302121914196 0.05435217469174387 236.7859299098779 780336.0606755796 0.013525760598988227 0.1394566059239289 1.7625650009844054e-05 4.753854857855256 -0.17922923199442675 LS(ph)PGESAYQK ddPTM_PC-9_AZD4547_30min_R2 3 LSPGESAYQK 10 0 A0A0G2JHC2;Q6NYC8;Q6NYC8-2 A0A0G2JHC2 PPP1R18 Phostensin 1 LS(1)PGESAYQK;LS(1)PGESAYQK;LS(0.983)PGES(0.017)AYQK 126.71 0.00033715 132813000.0 127032.0 128170.0 139965.0 193665.0 163302.0 184348.0 153966.0 192136.0 156367.0 160365.0 True False 167425.53357025597 169598.44599904318 138108.97264849348 149018.52634442336 140630.33609770425 172820.69041771968 167668.6757283358 162445.7960460475 164632.24039044246 154750.67016130724 1.0819050631298517 1.095946439664908 0.8924612249144577 0.9629588433387146 0.9087542945766607 1.1167686074482057 1.0834762495927368 1.049725961617608 1.0638547814935793 1.0 17.23958613160689 -6.774860222619035 24.999887015200798 1.067167428008562 0.9876357693656571 0.23749910555019582 0.06637789841775066 364.20504976723583 678424.3400297518 0.025047373823424042 0.022214008344542555 1.6793444270041603e-07 6.774860222619035 -0.07953165864290479 LS(ph)PGESAYQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LSPGESAYQK 10 0 A0A0G2JHC2;Q6NYC8;Q6NYC8-2 A0A0G2JHC2 PPP1R18 Phostensin 1 LS(1)PGESAYQK;LS(1)PGESAYQK;LS(0.999)PGES(0.001)AYQK;LS(0.993)PGES(0.007)AYQK;LS(1)PGESAYQK 143.0 0.00012795 144548000.0 200697.0 199664.1 242555.0 223050.0 272251.0 211479.0 246498.0 204405.0 195031.0 164900.3 True False 234671.03815356363 219485.43231393295 248338.4310949605 210553.23163785646 218905.37092015578 200388.6689524975 223147.92494902498 199039.58533499963 197882.9594125982 194795.41903994296 1.2047051173490078 1.126748428662623 1.2748679220430668 1.0808941641213972 1.1237706307419326 1.0287134571239975 1.1455501677032165 1.0217878136763905 1.0158501693103066 1.0 17.5716002247212 -6.587438820441706 0.42205442384247105 0.998292159612488 1.223189116599345 0.5863097931655501 0.0551381118477892 1.0558107814505786 0.3747452270439872 0.0533732149164403 0.09890771633064577 2.585599050191204e-07 6.587438820441706 0.22489695698685697 LS(ph)PGESAYQK ddPTM_PC-9_Lapatinib_30min_R1 4 LSPGESAYQK 10 0 A0A0G2JHC2;Q6NYC8;Q6NYC8-2 A0A0G2JHC2 PPP1R18 Phostensin 1 LS(1)PGESAYQK;LS(1)PGESAYQK;LS(1)PGESAYQK;LS(0.997)PGES(0.003)AYQK 158.06 0.00013692 219768000.0 154735.0 178919.0 202786.0 174233.0 210547.0 191462.0 193836.0 193719.0 193555.0 155660.0 True False 152528.45052507654 178504.7240482508 186113.7178565971 187046.67604424927 198163.0394113287 183273.61657972104 203871.87963316793 202719.8919459789 171754.79767549166 182565.62359608783 0.8354719115277355 0.9777564939781793 1.0194346240580272 1.0245448861614572 1.0854345714598983 1.0038780191455956 1.11670464360924 1.1103946512651297 0.9407838907037928 1.0 17.47805561141066 -3.9253631203337993 0.9869077014451773 1.0493421533206662 3.974866644659451e-07 0.5861686197286511 0.051408752999885406 5.858793363406519 1.3162977440121497 0.01616191391772719 9.776267937845521 0.00011875089176601197 3.9253631203337993 -1.0493417558340017 LS(ph)PGETPER ddPTM_PC-9_AZD4547_30min_R2 1 LSPGETPER 9 0 A0A0G2JHC2;Q6NYC8;Q6NYC8-2 A0A0G2JHC2 PPP1R18 Phostensin 1 LS(0.996)PGET(0.004)PER 80.706 0.018298 3409000.0 13523.0 14891.0 20667.0 21155.0 28633.0 19981.0 21996.0 21183.0 17906.0 22838.0 True False 17823.032704126315 19704.224540623785 20392.94207642208 16278.041591491863 24657.80219155648 18731.584911344034 23953.6013881018 17909.654086914645 18852.474604176485 22038.448571346195 0.8087244728877762 0.8940840130753439 0.9253347398934625 0.7386201228636456 1.1188538118611442 0.8499502517476817 1.0869005279820667 0.8126549393408891 0.8554356511595816 1.0 14.427735046416537 -2.970291062947095 0.555895019184497 0.9325110686203439 6.151576191573056e-09 0.09704181314034999 0.11210443841534327 69.02812392983786 3.185841358068286 0.054342876595302486 64.12676870470979 0.001070801416586518 2.970291062947095 -0.9325110624687678 LS(ph)PGETPER ddPTM_PC-9_Lapatinib_30min_R1 2 LSPGETPER 9 0 A0A0G2JHC2;Q6NYC8;Q6NYC8-2 A0A0G2JHC2 PPP1R18 Phostensin 1 LS(0.977)PGET(0.023)PER;LS(0.776)PGET(0.224)PER 112.11 0.0021902 6896400.0 42756.0 39766.0 50218.0 35985.0 66103.0 55319.0 50723.0 54250.0 66014.0 48461.0 True False 42146.291599509874 39673.92427021575 46089.269887085815 38631.456942440964 62214.95150349831 52953.135324887415 53349.18875045489 56770.65304936184 58578.80816176228 56837.41927977647 0.7415236675692294 0.6980247304143923 0.8108965971909461 0.6796835154017375 1.094612533289935 0.9316597409926538 0.9386279220006257 0.9988253120697479 1.0306380709056124 1.0 15.794553429612312 -6.255148656087867 24.99999480879168 0.99261018720583 0.7356647673611272 0.8552008475532062 0.05368214604506443 186.4021494942509 740781.3612003493 0.01582140439344769 0.019923121492422986 5.557140075346601e-07 6.255148656087867 -0.25694541984470287 LS(ph)PGSYPTVIQQQNATSQR ddPTM_PC-9_AZD4547_30min_R2 3 LSPGSYPTVIQQQNATSQR 19 0 Q13469-3;Q13469-4;Q13469-2;Q13469;Q13469-5 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 LS(1)PGSYPTVIQQQNATSQR;LS(1)PGSYPTVIQQQNATSQR;LS(0.998)PGS(0.002)YPTVIQQQNATSQR 199.09 4.8166e-15 81355900.0 50416.0 51811.0 86904.0 109459.0 107842.0 91219.0 74050.0 100414.0 87457.0 110012.0 True False 66447.23928205515 68557.89253067353 85751.59617793505 84224.91867469206 92869.99978842001 85515.06150982907 80640.30654614192 84897.32358416871 92079.79847299578 106160.51336504654 0.6259129423533192 0.6457946590266422 0.8077541588657092 0.7933733174883384 0.8748073727665069 0.8055260736708626 0.7596073529604165 0.7997071688249884 0.8673639148330753 1.0 16.695887726778054 -2.155879714302394 0.10976544678609974 1.0453900190718146 2.038308457159262e-25 0.7139570719759544 0.055049875699724055 63.34249603392463 0.5613868287305602 0.6217137506846995 9.89940620672734 0.006984258189311454 2.155879714302394 -1.0453900190718146 LS(ph)PGSYPTVIQQQNATSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LSPGSYPTVIQQQNATSQR 19 0 Q13469-3;Q13469-4;Q13469-2;Q13469;Q13469-5 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 LS(1)PGSYPTVIQQQNATSQR;LS(1)PGSYPTVIQQQNATSQR;LS(0.464)PGS(0.456)Y(0.08)PTVIQQQNATSQR;LS(1)PGSYPTVIQQQNATSQR;LS(0.471)PGS(0.471)Y(0.051)PT(0.008)VIQQQNATSQR;LS(0.388)PGS(0.329)Y(0.28)PT(0.003)VIQQQNATSQR 212.37 1.5369000000000002e-21 49940900.0 62088.799999999996 69989.3 94106.0 107781.0 121971.2 120340.0 108837.0 121898.5 106055.8 90677.4 True False 72599.20753030175 76937.3751608302 96349.84393899221 101742.38000071667 98071.81893758512 114029.15855353742 98527.17144835657 118698.79353713678 107606.66543713887 107116.49481809633 0.677759365199437 0.7182588945940037 0.8994865272861301 0.9498292506069593 0.9155622493447836 1.0645340733673192 0.9198132520642501 1.1081280594432197 1.0045760517077686 1.0 16.70882113155514 -4.971293066921789 0.6814450502657264 1.0223712724471095 0.47952680934363795 0.8285841311552765 0.054015439225161145 0.9338106521279049 0.38965645224446666 0.023704876573112467 0.37769300916790066 1.0683337120222504e-05 4.971293066921789 -0.5428444631034715 LS(ph)PGSYPTVIQQQNATSQR ddPTM_PC-9_Lapatinib_30min_R1 1 LSPGSYPTVIQQQNATSQR 19 0 Q13469-3;Q13469-4;Q13469-2;Q13469;Q13469-5 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 LS(0.997)PGS(0.003)YPTVIQQQNATSQR 135.95 8.979700000000001e-05 29969000.0 25913.0 26508.0 32074.0 31836.0 25239.0 32617.0 19623.0 25706.0 35028.0 20427.0 True False 25543.47586813779 26446.62235464667 29436.9995292204 34177.32564178272 23754.49164178318 31222.04694394064 20638.982923923595 26900.394604366767 31082.777778807664 23957.77973273341 1.066187107198329 1.1038845272674733 1.2287031543662101 1.4265648162332167 0.9915147357886225 1.3032112028846352 0.8614731061962576 1.1228250240406408 1.2973980947132342 1.0 14.548206593310711 LS(ph)PGTDSSSNLGGVK ddPTM_PC-9_AZD4547_30min_R2 4 LSPGTDSSSNLGGVK 15 0 A0A1W2PRB5;A0A0J9YVS1;A0A3B3IT55;A0A0G2JNB1;A0A0G2JNT7;Q7Z3B3;A0A0G2JQF5;A0A0G2JQF4;A0A1W2PRR3;I3L233;A0A1W2PPV8 A0A1W2PRB5 KANSL1 KAT8 regulatory NSL complex subunit 1 1 LS(0.997)PGT(0.003)DSSSNLGGVK;LS(0.999)PGT(0.001)DSSSNLGGVK;LS(0.968)PGT(0.021)DS(0.004)S(0.004)S(0.004)NLGGVK;LS(0.768)PGT(0.231)DSS(0.001)SNLGGVK 205.66 7.4807e-13 47890700.0 227260.0 217624.0 274502.0 247480.0 263553.0 281382.0 266987.0 326512.0 260031.0 252803.0 True False 299523.95269834663 287966.7021307308 270861.92412357917 190427.30952788523 226963.21520592654 263787.13905829575 290748.32577764767 276057.07289933774 273775.70779619215 243952.44391724467 1.2277964831537138 1.1804214686548373 1.110306253851111 0.7805919320590343 0.9303584402004133 1.0813055808031977 1.191823787903012 1.1316019977770087 1.1222503181360395 1.0 17.896240410701893 -5.359894431695356 3.9631092362332794 1.038307207318378 1.205311069678903 0.26498754342038966 0.11113871485492648 0.34768019231982644 9.667812616346444 0.03395229235505731 0.07754896536242724 4.366219534081048e-06 5.359894431695356 0.167003862360525 LS(ph)PGTDSSSNLGGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LSPGTDSSSNLGGVK 15 0 A0A1W2PRB5;A0A0J9YVS1;A0A3B3IT55;A0A0G2JNB1;A0A0G2JNT7;Q7Z3B3;A0A0G2JQF5;A0A0G2JQF4;A0A1W2PRR3;I3L233;A0A1W2PPV8 A0A1W2PRB5 KANSL1 KAT8 regulatory NSL complex subunit 1 1 LS(0.986)PGT(0.014)DSSSNLGGVK;LS(0.953)PGT(0.047)DSSSNLGGVK;LS(0.872)PGT(0.114)DS(0.005)S(0.005)S(0.005)NLGGVK 180.56 2.0901999999999997e-05 35004700.0 157620.0 167589.0 152604.0 160268.0 181642.0 135811.0 185432.0 137381.0 133064.0 115403.0 True False 184301.95286309576 184226.12836288402 156242.65811389286 151288.70355586632 146050.55402800709 128688.8320783984 167866.5385485789 133774.89431720166 135009.809267644 136324.6503703549 1.3519341686364155 1.3513779632839296 1.1461071617600078 1.109767772335072 1.071343690456786 0.9439879855095011 1.2313733289800026 0.9812964416470074 0.9903550744554352 1.0 17.056686929841902 -5.396292823166011 1.3717777451503839 1.0418661836629082 1.3917513492171778 0.7168800792395853 0.07604669140904734 0.29422292660900673 0.9442129742236731 0.023783119305556568 0.1039440041988051 4.015199946007112e-06 5.396292823166011 0.34988516555426963 LS(ph)PGTDSSSNLGGVK ddPTM_PC-9_Lapatinib_30min_R1 3 LSPGTDSSSNLGGVK 15 0 A0A1W2PRB5;A0A0J9YVS1;A0A3B3IT55;A0A0G2JNB1;A0A0G2JNT7;Q7Z3B3;A0A0G2JQF5;A0A0G2JQF4;A0A1W2PRR3;I3L233;A0A1W2PPV8 A0A1W2PRB5 KANSL1 KAT8 regulatory NSL complex subunit 1 1 LS(0.995)PGT(0.005)DSSSNLGGVK;LS(0.99)PGT(0.01)DSSSNLGGVK;LS(0.88)PGT(0.118)DS(0.001)S(0.001)SNLGGVK 218.34 6.5022e-18 35669500.0 144371.0 220923.0 206215.0 204693.0 229750.0 234256.0 211959.0 237714.0 217780.0 193030.0 True False 142312.24306560121 220411.4663669684 189260.79871291944 219746.80605583114 216236.5567058793 224237.41695740743 222933.199896648 248759.06025762236 193251.32307493215 226394.97830369283 0.6286015888333858 0.9735704741264272 0.835976133971662 0.9706346302480984 0.9551296513998349 0.9904699240131061 0.9847091201713799 1.0987834717956053 0.8536025159343384 1.0 17.788482432356133 -4.35838125177831 1.7183523896822503 0.9695338371743983 3.06560165541739e-32 0.6458806151461054 0.07281626895712504 2.250600905848043 2.486082211953436 0.019387290804350463 5.153446127797448 4.381458960990726e-05 4.35838125177831 -0.9695338371743983 LS(ph)PHKVQGR ddPTM_PC-9_Lapatinib_30min_R1 3 LSPHKVQGR 9 1 Q9GZP8;Q9GZP8-2;K7EQZ3 Q9GZP8 IMUP Immortalization up-regulated protein 1 LS(1)PHKVQGR;LS(1)PHKVQGR;LS(1)PHKVQGR 62.107 0.029748 419114000.0 739239.0 750978.0 759755.0 702482.0 713507.0 732540.0 604740.0 697948.0 726769.0 622394.0 True False 728697.3163001713 749239.1565809502 697290.876639111 754144.8696912568 671539.9210687345 701210.9718341435 636050.4781844554 730377.2120644439 644912.6220031475 729973.9736121236 0.998251092014096 1.0263916025300146 0.9552270380116606 1.0331119970750855 0.9199504987085492 0.9605972228904923 0.8713330901882606 1.0005524011360636 0.8834734460626482 1.0 19.477485501703327 -6.269448013840666 24.96958663311322 0.9370101333423715 1.0014688454171203 0.33021896042431376 0.044501089044981484 661.3059476297677 2061839.073873908 0.012686134591707752 0.014656145746468464 5.377147951051478e-07 6.269448013840666 0.06445871207474885 LS(ph)PIPEEVPK ddPTM_PC-9_AZD4547_30min_R2 4 LSPIPEEVPK 10 0 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 LS(1)PIPEEVPK;LS(1)PIPEEVPK;LS(1)PIPEEVPK;LS(1)PIPEEVPK 147.26 0.00011552 184929000.0 666930.0 778880.0 735540.0 545497.0 628240.0 856500.0 817570.0 790860.0 787350.0 625148.0 True False 878999.8669942281 1030637.7281714496 725786.2590067021 419741.0944946371 541019.7202117656 802942.9196019302 890332.1461570477 668650.7591548566 828967.7135931171 603261.7588002419 1.4570787128001783 1.7084420040500607 1.2031033766339427 0.6957860139011829 0.8968241601916517 1.331002517379539 1.4758637244431458 1.1083924173888617 1.374142652837395 1.0 19.202424606216354 -5.346808688629555 5.8822621163706135 1.131217306199614 1.5801850945711247 0.3856693235987507 0.22668519513580934 0.2337429238866014 12.65519689637658 0.06556727863932402 0.13972320581687564 4.499780313826068e-06 5.346808688629555 0.44896778837151063 LS(ph)PIPEEVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LSPIPEEVPK 10 0 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 LS(1)PIPEEVPK;LS(1)PIPEEVPK;LS(1)PIPEEVPK;LS(1)PIPEEVPK 141.71 0.00012548 175963000.0 272344.0 396646.0 290413.0 282208.0 296397.0 210237.0 317154.0 173006.0 197348.0 205370.0 True False 318446.4601608103 436022.3935379078 297337.5473174352 266396.800690681 238320.1355536678 199211.80161891377 287110.8771238836 168464.77581500902 200233.8411542649 242601.9552919746 1.3126294047282343 1.7972748530124136 1.2256189236380457 1.0980818368511045 0.9823504318703714 0.8211467272766199 1.183464810818783 0.6944081535215142 0.8253595520830855 1.0 17.88823165258966 -5.688889204094868 1.8032039179777826 0.9143783686763546 1.557647570003172 0.6692740084351981 0.17207818482766987 0.1953230897306348 1.2828982231494634 0.051449599486674456 0.11560827168620182 2.046966786141848e-06 5.688889204094868 0.6432692013268174 LS(ph)PIPEEVPK ddPTM_PC-9_Lapatinib_30min_R1 4 LSPIPEEVPK 10 0 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 LS(1)PIPEEVPK;LS(1)PIPEEVPK;LS(1)PIPEEVPK;LS(1)PIPEEVPK 146.16 0.00011139 191879000.0 413767.0 695520.0 559140.0 538080.0 675240.0 663540.0 731980.0 755400.0 599610.0 524060.0 True False 407866.6067044261 693909.5661726231 513169.66754281655 577652.1981822591 635523.7107729181 635161.9409872885 769878.3427943526 790498.6417232787 532075.6076267804 614643.0727339427 0.6635828577555241 1.1289634536774356 0.8349067781081942 0.9398173083003319 1.033971973272387 1.0333833881216257 1.252561652358532 1.2861100641826606 0.8656659958113564 1.0 19.229389345569224 -6.467915359603354 1.657263720254191 1.1198762736035353 0.8982761804786314 0.2582124208684152 0.15562440986697834 0.49633908615151157 2.7467405409490326 0.05857828183395435 0.06697172961523451 3.404745389023349e-07 6.467915359603354 -0.2216000931249038 LS(ph)PISHGNTIALFFR ddPTM_PC-9_AZD4547_30min_R2 2 LSPISHGNTIALFFR 15 0 Q9BQ70 Q9BQ70 TCF25 Transcription factor 25 1 LS(1)PISHGNTIALFFR;LS(1)PISHGNTIALFFR 131.82 4.7701e-06 10675600.0 17117.6 16701.0 20524.5 20873.8 19756.4 20600.6 20423.0 22375.6 22697.0 18587.8 True False 22560.640731801563 22099.271644144646 20252.331719529942 16061.667906995186 17013.56488028731 19312.441225395807 22240.607435406564 18917.965160136297 23896.717083156134 17937.046779685996 1.2577678482364145 1.2320462735912825 1.1290783799742354 0.8954466197403963 0.9485153876922179 1.0766789796895366 1.2399258199289764 1.0546867270013036 1.332254823030264 1.0 14.130654758824326 -5.323219081135573 3.9345657470341324 1.077895223000718 1.247840815680412 0.2231642253829127 0.1219089572631976 0.3390340087883726 10.498388234188681 0.03438354789063923 0.08137609571277835 4.7509550215231836e-06 5.323219081135573 0.169945592679694 LS(ph)PISHGNTIALFFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSPISHGNTIALFFR 15 0 Q9BQ70 Q9BQ70 TCF25 Transcription factor 25 1 LS(1)PISHGNTIALFFR;LS(0.993)PIS(0.007)HGNTIALFFR 122.16 3.0883e-05 11346000.0 37421.0 48665.0 43362.0 42473.0 51799.0 30842.5 49761.0 32219.1 34044.0 33283.9 True False 43755.6362015601 53496.13958421939 44395.91453130073 40093.3755093239 41649.35779223277 29225.065004881842 45047.277841558185 31373.382763958245 34541.82909507965 39318.00759479257 1.112865042717863 1.3606014866151208 1.1291496504309313 1.019720427406246 1.0592947186303756 0.7432997446379385 1.1457161895335821 0.7979392823585867 0.878524401619336 1.0 15.26290259578693 -5.878514103179983 1.4036139544383868 0.9212012782262633 1.2418310399964136 0.484343914771009 0.12436951731024276 0.33914011400163224 1.3554557362107107 0.041216652827014096 0.08485406492391011 1.322774751826776e-06 5.878514103179983 0.32062976177015035 LS(ph)PISHGNTIALFFR ddPTM_PC-9_Lapatinib_30min_R1 2 LSPISHGNTIALFFR 15 0 Q9BQ70 Q9BQ70 TCF25 Transcription factor 25 1 LS(0.955)PIS(0.045)HGNTIALFFR;LS(0.801)PIS(0.199)HGNTIALFFR 78.22800000000001 0.006864100000000001 6260100.0 20195.9 25941.6 24294.8 23647.5 22888.2 26230.5 31396.2 24541.1 25098.8 29632.1 True False 19907.902762525533 25881.533819047138 22297.375324640016 25386.616035747484 21541.96107593257 25108.682661281993 33021.74161321358 25681.36909769023 22271.908841918954 34753.969002708625 0.5728238625342035 0.7447072826999991 0.6415778100884598 0.7304666708360396 0.6198417531607296 0.7224695015215411 0.9501574226138015 0.7389478046576118 0.6408450453582192 1.0 15.08489012669628 -7.009817993888594 24.268046203361262 0.8143875480228708 0.6693657402953637 0.3638939738324465 0.10518954156179923 407.60337251703135 1007511.8016604368 0.03752418200750137 0.031225276140143608 9.77646851814541e-08 7.009817993888594 -0.14502180772750717 LS(ph)PLPVVSR ddPTM_PC-9_AZD4547_30min_R2 2 LSPLPVVSR 9 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 LS(0.997)PLPVVS(0.003)R;LS(1)PLPVVSR 77.744 0.022612 7964800.0 20618.3 29393.0 27820.0 23485.0 23604.0 33353.0 29566.0 33369.0 30381.0 20800.2 True False 27174.490512718152 38893.712438557166 27451.088622734904 18070.896089633028 20326.992034697705 31267.431637458452 32197.31672306862 28212.58779333686 31986.87763595923 20071.99132908814 1.3538512480989933 1.9377107034812617 1.3676315504856285 0.9003041000443666 1.012704305289332 1.5577643057341293 1.6040918011163432 1.4055699472354517 1.5936075853920955 1.0 14.29289613217859 -11.428910232985325 2.546430760814435 0.7629659949188102 1.4113377462007424 0.1630735309107908 0.2818151632540927 31570631.389636666 16131564.373710973 44706635.23989433 0.07727931442259531 3.724686861568287e-12 11.428910232985325 0.6483717512819321 LS(ph)PLPVVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LSPLPVVSR 9 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 LS(1)PLPVVSR;LS(0.998)PLPVVS(0.002)R;LS(0.999)PLPVVS(0.001)R 84.31 0.013306 8507800.0 39237.0 67192.0 50919.0 40919.0 43884.0 30600.1 43023.0 31366.1 34126.3 26935.3 True False 45879.04913392513 73862.377703542 52133.10207138286 38626.441091187895 35285.24522392988 28995.37688760265 38947.549980453696 30542.773110130067 34625.33257688334 31818.45667028252 1.4419005173426522 2.32136896106992 1.6384547689289282 1.2139633763966882 1.1089552705076746 0.9112754018231016 1.2240552828833315 0.9599074344374501 1.0882153378992248 1.0 14.957576240104405 -5.727912627938987 2.7683733891897258 1.0567801916348456 1.9012389991551875 0.7133132754431714 0.21606016918631873 0.12395740889455463 1.9332591508044563 0.05845236232263653 0.10704450924547884 1.871058525061249e-06 5.727912627938987 0.8444588075203419 LS(ph)PLPVVSR ddPTM_PC-9_Lapatinib_30min_R1 2 LSPLPVVSR 9 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 LS(1)PLPVVSR;LS(1)PLPVVSR 132.32 0.0012054000000000001 8234400.0 16136.199999999999 39440.0 28555.0 24992.0 32669.0 37705.0 41252.0 41153.0 33235.0 30596.0 True False 15906.094828983341 39348.67910318637 26207.31812548757 26829.995050868005 30747.473649725216 36092.44504464794 43387.826712413786 43065.118616412685 29491.72431993469 35884.47783339266 0.4432583609780652 1.096537597283081 0.730324633596872 0.7476768973882375 0.8568460656577493 1.0057954643291969 1.2090973404673262 1.2001043687011104 0.8218518451588244 1.0 15.131072307291266 -6.739500354702464 2.827979032309763 1.0774013088086165 0.7795609948881166 0.37128190958353813 0.17954894433051596 0.285860677083268 4.689259240264799 0.06416885537971702 0.06036372897091621 1.821795585171405e-07 6.739500354702464 -0.2978403139204999 LS(ph)PNPPK ddPTM_PC-9_Lapatinib_30min_R1 1 LSPNPPK 7 0 A0A0U1RRJ4;A0A0U1RRD6;F6VDE0;A0A0U1RQZ9;B1ALF6;B4DNT1;A0A1W2PS06;A0A0U1RRG6;A0A0U1RR26;B1ALG2;F6T8Q0;A0A0U1RQX3;A0A0U1RR83;B1ALG1;A0A0U1RRN2;A0A0U1RQW7;F6XE55;A0A0U1RR09;A0A0U1RQU0;F6UH26;A0A0A0MSS5;A0A0U1RRF8;P51531-2;P51531 A0A0U1RRJ4 SMARCA2 Probable global transcription activator SNF2L2 1 LS(1)PNPPK 86.13600000000001 0.020937 0.0 20997.0 42578.0 41249.0 38512.0 43412.0 42084.0 39461.0 45545.0 41744.0 36272.0 True False 20697.578929621795 42479.4132569845 37857.66644574461 41344.300952265854 40858.59151127585 40284.16542259553 41504.09749584411 47661.18697019699 37042.35113619237 42541.56687059805 0.4865260133125611 0.9985389909637649 0.8898982625839612 0.9718565627360645 0.9604392719139511 0.9469365701816054 0.9756128076356545 1.1203439477246262 0.8707331173030587 1.0 15.37658555047878 -4.75945308884696 24.99929963888808 0.9708802120383915 0.48652539900967257 0.836351915523445 0.06422272418720003 19.108573267776585 240436.87829940912 0.015510218245095131 0.09842532057510298 1.739990636320145e-05 4.75945308884696 -0.4843548130287189 LS(ph)PNPPNLTK ddPTM_PC-9_AZD4547_30min_R2 1 LSPNPPNLTK 10 0 P51532;A0A2R8Y7Y7;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8YG32;A0A2R8Y440;A0A2R8Y7F3;K7EP28;A0A2R8YF80;A0A2R8Y6N0;A0A2R8Y526;A0A2R8YF58;A0A2R8Y4C5;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8Y523;A0A2R8Y5K3;K7EQF0;A0A2R8YFK5;A0A0A0MT49;P51532-5;P51532-2;P51532-3;P51532-4;A0A2R8YF38 P51532 SMARCA4 Transcription activator BRG1 1 LS(1)PNPPNLTK 108.98 0.0058892 0.0 22375.0 29846.0 22192.0 19385.0 22263.0 25796.0 26463.0 29786.0 23096.0 24376.0 True False 29489.78457108823 39493.13582965934 21897.719580004792 14916.087745264473 19172.16673735278 24182.97204209151 28818.155734376145 25183.258114187774 24316.8074085815 23522.60365947695 1.2536785892409992 1.6789440659451857 0.930922439412122 0.6341172074824708 0.8150529173937157 1.0280737792539605 1.225126102176435 1.0705982415361477 1.0337634285983717 1.0 14.52176013694825 -5.274541760978651 24.81204326304003 0.963783213908392 1.4663113227615865 0.5605750763738213 0.17673634152395193 474.84906567348946 899224.3732622339 0.05088580946455653 0.10696157738637598 5.314448942614891e-06 5.274541760978651 0.5025281088531945 LS(ph)PNPPNLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSPNPPNLTK 10 0 P51532;A0A2R8Y7Y7;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8YG32;A0A2R8Y440;A0A2R8Y7F3;K7EP28;A0A2R8YF80;A0A2R8Y6N0;A0A2R8Y526;A0A2R8YF58;A0A2R8Y4C5;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8Y523;A0A2R8Y5K3;K7EQF0;A0A2R8YFK5;A0A0A0MT49;P51532-5;P51532-2;P51532-3;P51532-4;A0A2R8YF38 P51532 SMARCA4 Transcription activator BRG1 1 LS(1)PNPPNLTK;LS(1)PNPPNLTK 95.273 0.0059802 13792600.0 52181.0 104423.0 73511.0 55345.0 63257.0 36369.0 55842.0 41923.0 37172.0 39555.0 True False 61014.21267827172 114789.42533243507 75263.78103201986 52244.19908091096 50862.24494417402 34461.74561603462 50552.241498930685 40822.565671090175 37715.57017748505 46726.00838279227 1.3057869651185814 2.45664950431992 1.610747068644048 1.1180967707087701 1.0885210764740818 0.7375281306657857 1.0818865819821986 0.8736583133029581 0.8071643926549164 1.0 15.511938178311876 -5.738174845037369 2.7061106721439456 0.9347235932009273 1.911282774732399 0.6571270774852549 0.2812008703232897 0.14298033286930106 2.133209195208317 0.07718936492842282 0.14095965980077443 1.8273643792143734e-06 5.738174845037369 0.9765591815314717 LS(ph)PNPPNLTK ddPTM_PC-9_Lapatinib_30min_R1 1 LSPNPPNLTK 10 0 P51532;A0A2R8Y7Y7;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8YG32;A0A2R8Y440;A0A2R8Y7F3;K7EP28;A0A2R8YF80;A0A2R8Y6N0;A0A2R8Y526;A0A2R8YF58;A0A2R8Y4C5;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8Y523;A0A2R8Y5K3;K7EQF0;A0A2R8YFK5;A0A0A0MT49;P51532-5;P51532-2;P51532-3;P51532-4;A0A2R8YF38 P51532 SMARCA4 Transcription activator BRG1 1 LS(1)PNPPNLTK 84.71799999999999 0.012365000000000001 8207500.0 10603.0 30782.0 20331.0 19591.0 29352.0 22164.0 28701.0 29174.0 21192.0 20534.0 True False 10451.799275647938 30710.72617024046 18659.463659929537 21031.787493660173 27625.57306825231 21216.09738680751 30186.997344928463 30529.530544923196 18805.133798346797 24083.274540164875 0.43398580447259993 1.2751889747809275 0.7747893098511259 0.8732943461896934 1.1470854190604258 0.8809473708163883 1.253442396073844 1.2676652626289493 0.780837911679516 1.0 14.555743944474159 -6.243541658330752 21.542372461824602 1.0695994784516383 0.8658393572631995 0.15985325261391137 0.23775188606810424 270.5872077033188 325685.4984021969 0.06740811875524003 0.08670053105014745 5.707663245834079e-07 6.243541658330752 -0.20376012118843878 LS(ph)PQQESSASSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSPQQESSASSK 12 0 F5H212;P15822 F5H212 HIVEP1 Zinc finger protein 40 1 LS(1)PQQESSASSK 115.09 0.0016474 0.0 6199.2 11693.0 8277.2 7827.8 10742.0 5647.0 8406.9 5276.0 6125.1 3641.4 True False 7248.602120218893 12853.803763655143 8474.559839455806 7389.233744070009 8637.182212092213 5350.86137902465 7610.537571314788 5137.510590384079 6214.667999949256 4301.556994693458 1.68511125835622 2.988174695700189 1.970114507354035 1.7178044492228304 2.007919974731783 1.2439359482219223 1.7692518268857989 1.194337444958158 1.4447484963272308 1.0 12.07064323795203 -6.444583019239109 0.44018663875628794 1.112966467867473 2.4929935281865783 0.5068215035434762 0.37499342281677944 1.1358339857165036 0.4271698981092795 0.3389659035379996 0.6897176103488188 3.5926671317467154e-07 6.444583019239109 1.3800270603191052 LS(ph)PSPTSQR ddPTM_PC-9_AZD4547_30min_R2 1 LSPSPTSQR 9 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 LS(0.769)PS(0.23)PT(0.001)SQR 75.652 0.025660000000000002 195450000.0 35389.0 25046.0 34947.0 42867.0 41128.0 39981.0 32157.0 41389.0 30431.0 32277.0 True False 46641.96586307225 33141.629698775316 34483.579946035825 32984.675438547965 35418.08712095609 37480.98174968447 35018.91070363656 34993.28107460275 32039.520533882216 31146.99205435418 1.4974789790833736 1.0640394950799845 1.1071239202122314 1.0590003484441408 1.1371270477466484 1.2033579898911886 1.1243111579611138 1.1234882974746476 1.0286553667195373 1.0 14.926805224731297 -4.757997507759087 24.99998832949431 1.1029912235363188 1.4974795300230688 0.8212528336836017 0.05631692860087219 40.21049453889266 292022.69973209954 0.014112975111339441 0.09997808616838014 1.7458321715186265e-05 4.757997507759087 0.39448830648674993 LS(ph)PSPTSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSPSPTSQR 9 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 LS(0.942)PS(0.058)PTSQR 123.62 0.0014850999999999998 312140000.0 32193.0 37840.0 49200.0 37537.0 43025.0 28970.0 37040.0 37607.0 25431.0 28955.0 True False 37642.639059266796 41596.50512415212 50373.11459203907 35433.92358659596 34594.56010754677 27450.762201229678 33531.30305362262 36619.856097910204 25802.880264274776 34204.31229234613 1.1005231953659265 1.2161187387316699 1.4727123925631747 1.0359490137892637 1.0114093162249593 0.8025526713300508 0.9803238482630126 1.070621031199759 0.7543750636977042 1.0 15.061890603215915 -5.952987471959721 7.740764959284929 0.9432780843901722 1.2593113394075088 0.5809687414334361 0.12394525445454965 0.1677962737382464 23.573700404706255 0.03516678225983128 0.052193356229263584 1.1143266779747072e-06 5.952987471959721 0.3160332550173366 LS(ph)PSPTTEDPR ddPTM_PC-9_AZD4547_30min_R2 1 LSPSPTTEDPR 11 0 F6RRE2;E7EV10;Q9BTC8;E7EQY4;Q9BTC8-2 F6RRE2 MTA3 Metastasis-associated protein MTA3 1 LS(0.804)PS(0.187)PT(0.003)T(0.006)EDPR 130.01 0.00023089 8722200.0 30861.0 51330.0 48078.0 46158.0 47083.0 56117.0 51548.0 65315.0 48581.0 52445.0 True False 40674.1560513231 67921.41868714112 47440.45430639287 35516.986233991105 40546.33816173836 52607.99511885754 56135.672138292044 55222.0675393868 51148.89247992284 50608.91651301565 0.8036954523786828 1.3420840311740923 0.9373932021285635 0.7017930570565922 0.8011698521803092 1.0395005217179027 1.1092051758083978 1.0911529300411864 1.010669581649082 1.0 15.627103967548885 -6.972030505151052 24.46661280726867 1.0623530246873987 0.92901729383561 0.14069666751804477 0.16246824550907377 382.27642862381873 334398.7411640523 0.06180496278770743 0.054505712884813054 1.0665212053967109e-07 6.972030505151052 -0.13333573085178863 LS(ph)PSTSGPHSHDYLPQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSPSTSGPHSHDYLPQER 18 0 Q5JR04;Q9HCE1 Q5JR04 MOV10 Putative helicase MOV-10 1 LS(0.25)PS(0.25)T(0.25)S(0.25)GPHSHDYLPQER 80.545 0.0019993 5929900.0 5012.9 10764.0 19510.0 17549.0 19587.0 19985.0 14748.0 9068.4 11846.0 10327.0 True False 5861.484960711916 11832.578783202252 19975.19239208703 16565.786424625636 15749.067956455989 18936.951418418197 13350.96267372641 8830.364108764023 12019.225339569772 12199.203351512982 0.48048096189698786 0.9699468434334066 1.6374177736458213 1.3579400184825263 1.2909915100728886 1.5523104970677923 1.0944126668788239 0.7238476033493494 0.9852467405651625 1.0 13.574499317636958 -7.529495715690445 20.581777897515007 0.8945530192274107 1.240428352646118 0.16414133332332836 0.31151271836144756 34.20690666755585 106378.83218893554 0.15486147299178613 0.08997054229614077 2.9546380358023113e-08 7.529495715690445 0.34587533341870724 LS(ph)PSTSGPHSHDYLPQER ddPTM_PC-9_Lapatinib_30min_R1 1 LSPSTSGPHSHDYLPQER 18 0 Q5JR04;Q9HCE1 Q5JR04 MOV10 Putative helicase MOV-10 1 LS(0.841)PS(0.137)T(0.019)S(0.003)GPHSHDYLPQER 97.235 0.00067757 6590400.0 10418.0 11059.0 18623.0 8795.6 18430.0 19461.0 16938.0 14914.0 23870.0 10353.0 True False 10269.437409572784 11033.393564962938 17091.88882685887 9442.457765261466 17345.983634774122 18628.698395806747 17814.966761729484 15606.95888623378 21181.50923775661 12142.502255494637 0.8457430926089169 0.9086589677156689 1.4076084539432203 0.7776368961338783 1.4285345202983053 1.5341729409502085 1.4671577889695664 1.285316531785813 1.744410566460608 1.0 13.567778133894665 -6.28521919605663 23.05636542868817 1.4332713612121741 1.0096578763878041 0.4300316710323052 0.2381263189357321 272.04210779530644 263764.5979366822 0.07070453915392488 0.08023724544926829 5.185382575011319e-07 6.28521919605663 -0.42361348482437 LS(ph)PSWNPK ddPTM_PC-9_AZD4547_30min_R2 1 LSPSWNPK 8 0 Q96BY7 Q96BY7 ATG2B Autophagy-related protein 2 homolog B 1 LS(0.985)PS(0.015)WNPK 81.33800000000001 0.018025 5885700.0 49538.0 54238.0 64706.0 58942.0 53729.0 64582.0 59800.0 50563.0 47193.0 48714.0 True False 65290.053545589646 71769.37281810174 63847.95616185068 45353.83254482224 46269.655780048866 60543.677330685176 65122.0841520498 42749.65017215054 49687.52563358096 47008.537687387594 1.3888977780967433 1.5267305972242033 1.3582204276688468 0.9647999018057243 0.9842819635817566 1.2879293913226546 1.3853246102892938 0.9094018294387465 1.0569893912465211 1.0 15.520635182311114 -5.607572758276721 5.458692074310583 1.0982911553533847 1.454571025381687 0.5456244606194376 0.14369159393453293 0.1634564470896578 7.967822635188236 0.04238980702494163 0.07492094569612709 2.468466522824999e-06 5.607572758276721 0.3562798700283023 LS(ph)PTFPESIEHPLAR ddPTM_PC-9_AZD4547_30min_R2 1 LSPTFPESIEHPLAR 15 0 M9T4I7;Q5U5Q3 M9T4I7 MEX3C RNA-binding E3 ubiquitin-protein ligase MEX3C 1 LS(0.981)PT(0.019)FPESIEHPLAR 151.04 8.084e-05 1784200.0 8207.6 8390.3 13636.0 13445.0 13575.0 16203.0 11381.0 16050.0 14057.0 14119.0 True False 10817.446071314576 11102.300393740898 13455.177730395886 10345.4629731793 11690.345571556578 15189.823848581518 12393.88695208158 13569.841292308929 14800.024322065725 13624.69810748914 0.7939585879975212 0.8148657905042501 0.9875578617774972 0.7593168591010959 0.8580260259220497 1.1148741593204234 0.9096632346862046 0.9959737225186621 1.0862643858457708 1.0 13.733936642932331 -6.665454568430632 8.159352520680473 1.013817934968102 0.8433248406398284 0.5784889667190984 0.07616048571510779 0.19405682205667696 14.599721649734974 0.02498837121626179 0.024954443301487286 2.1604560283765456e-07 6.665454568430632 -0.17049309432827364 LS(ph)PTFPESIEHPLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSPTFPESIEHPLAR 15 0 M9T4I7;Q5U5Q3 M9T4I7 MEX3C RNA-binding E3 ubiquitin-protein ligase MEX3C 1 LS(0.968)PT(0.032)FPESIEHPLAR 113.33 0.00012785 1786600.0 3674.5 9072.0 6786.6 7262.2 9167.5 5801.7 8581.6 6936.8 6969.8 4826.4 True False 4296.520275316867 9972.608205240691 6948.41828232383 6855.322478370068 7371.194184449393 5497.448638690865 7768.688722596326 6754.716350147134 7071.7201394338545 5701.3881142386235 0.7535919655402435 1.7491544173839244 1.2187239568853203 1.2023953361900785 1.2928771093552818 0.9642298557015543 1.3625960146783964 1.1847494355414838 1.240350594931955 1.0 12.477097498977944 -5.502173224558587 24.91256182166646 1.1910448184542628 1.3095146046196362 0.001491979661770837 0.2515304056556765 2776.2226564801776 3340302.6954267416 0.0614896619647645 0.12570503908777625 3.1464930400750573e-06 5.502173224558587 0.1184697861653734 LS(ph)PTFPESIEHPLAR ddPTM_PC-9_Lapatinib_30min_R1 1 LSPTFPESIEHPLAR 15 0 M9T4I7;Q5U5Q3 M9T4I7 MEX3C RNA-binding E3 ubiquitin-protein ligase MEX3C 1 LS(0.862)PT(0.138)FPESIEHPLAR 132.64 3.4627e-06 1815900.0 4683.5 4991.5 7013.2 5573.0 6274.3 5900.9 6693.6 8006.8 7335.1 4716.1 True False 4616.71243115129 4979.9424884268465 6436.601767734885 5982.857010983011 5905.258009748417 5648.5322626697525 7040.161855963665 8378.825158260475 6508.943795972709 5531.271601191756 0.8346566149737761 0.9003250694386221 1.163674871135973 1.0816422411247997 1.067613097949499 1.0211995848210982 1.2727926530396385 1.5148099320335655 1.176753604825752 1.0 12.433395468891321 -4.192354503605889 0.4419230040841576 1.2397917489210368 0.26349585580282014 0.3991735037498667 0.1428492836178876 8.470609863690926 0.8687975988587276 0.10626127573807417 4.821388105160664 6.42163321636176e-05 4.192354503605889 -0.9762958931182166 LS(ph)PTSLVHPVMSTLPELSCK ddPTM_PC-9_AZD4547_30min_R2 1 LSPTSLVHPVMSTLPELSCK 20 0 C9JRJ5;Q9UGP4 C9JRJ5 LIMD1 LIM domain-containing protein 1 1 LS(0.826)PT(0.087)S(0.087)LVHPVMSTLPELSCK 97.25299999999999 0.00065474 0.0 18278.0 21548.0 28695.0 27575.0 32041.0 35876.0 28141.0 40859.0 30999.0 30081.0 True False 24090.023793982145 28512.96960589359 28314.485551020083 21218.009779503118 27592.660217918536 33632.668048615116 30645.4944836594 34545.18039641435 32637.543854287207 29027.873345943815 0.8298928242825734 0.9822617477376387 0.9754240420432516 0.7309529543082425 0.9505574138718009 1.1586335536121783 1.055726477735291 1.1900692821936087 1.1243518760511537 1.0 14.825151259965743 -6.637028389779046 4.980059247026104 1.1136157929736996 0.8880293057222578 0.623946385619846 0.08330601135935388 0.1398385584096342 5.529596746898511 0.027980349965116988 0.027876254974126 2.3065964018569934e-07 6.637028389779046 -0.22558648725144181 LS(ph)PTSLVHPVMSTLPELSCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSPTSLVHPVMSTLPELSCK 20 0 C9JRJ5;Q9UGP4 C9JRJ5 LIMD1 LIM domain-containing protein 1 1 LS(0.673)PT(0.164)S(0.164)LVHPVMSTLPELSCK;LS(0.967)PT(0.017)S(0.017)LVHPVMSTLPELSCK 89.365 0.00048143 13240100.0 74393.0 112156.0 138618.0 117152.0 149268.0 114850.0 135869.0 97866.0 101494.0 95336.0 True False 86986.26557127446 123290.10646681848 141923.17883169255 110588.35325190844 120020.00692930396 108827.06381813022 122998.50471362467 95297.1211975985 102978.15774221628 112619.66212063923 0.7723896869633117 1.0947476146283317 1.2601989400364486 0.9819631063485625 1.0657109484198009 0.9663238351892199 1.0921583531467847 0.8461854653365533 0.9143888003491355 1.0 16.78109920209976 -7.757977109215512 24.999958981584978 0.9102153461957976 1.0411316134745943 0.15063284624481976 0.12147878006759683 149.5379805798883 1079791.88831293 0.060182005039847136 0.03293450061952206 1.7459141741032084e-08 7.757977109215512 0.13091626727879668 LS(ph)PTSLVHPVMSTLPELSCK ddPTM_PC-9_Lapatinib_30min_R1 1 LSPTSLVHPVMSTLPELSCK 20 0 C9JRJ5;Q9UGP4 C9JRJ5 LIMD1 LIM domain-containing protein 1 1 LS(0.931)PT(0.034)S(0.034)LVHPVMSTLPELSCK 89.51100000000001 0.0011079 0.0 7469.0 13023.0 15322.0 11539.0 14648.0 16088.0 14443.0 17049.0 16151.0 14206.0 True False 7362.49069035315 12992.846043630736 14062.284304630388 12387.616552975584 13786.433439076032 15399.953742959711 15190.787869858255 17841.15878043447 14331.904302430134 16661.488171694855 0.4418867399168352 0.7798130580978629 0.8439992970447808 0.7434880021113672 0.8274431009408229 0.9242844087073636 0.9117305557174011 1.0708022354655982 0.8601815248878967 1.0 14.024229644721059 -4.21322030552273 0.4452349398925576 0.9674416822030016 9.509188996324952e-21 0.7354228437378173 0.08343745904132617 4.625417078540953 0.4868081764772611 0.05904232452035579 2.6193627068546554 6.120398421599533e-05 4.21322030552273 -0.9674416822030016 down LS(ph)PVGWVSSSQGK ddPTM_PC-9_AZD4547_30min_R2 1 LSPVGWVSSSQGK 13 0 Q00587-2;Q00587;B0QYC6;B0QYC7;B0QYC8 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 LS(1)PVGWVSSSQGK 81.904 0.011112 3740200.0 10765.0 16909.0 15742.0 16099.0 14590.0 17467.0 18757.0 23675.0 15085.0 18662.0 True False 14188.046074090056 22374.50357648295 15533.25079435993 12387.624277070552 12564.430341731886 16374.785728764622 20426.336662876223 20016.572747377817 15882.36230336213 18008.649060270705 0.787846219147589 1.2424309842232342 0.8625439222216946 0.6878708244917258 0.6976886661337949 0.9092734093469239 1.134251469641842 1.1114977409125506 0.8819296911282798 1.0 14.136402339408342 -7.063517129505395 7.601282301544239 1.0393359048673398 0.8619128651829299 0.21792463109591242 0.1575144638366009 0.5076577355158429 54.45030030776404 0.06527860541293996 0.050733999654511336 8.639385844225178e-08 7.063517129505395 -0.17742303968440998 LS(ph)PVPVPR ddPTM_PC-9_AZD4547_30min_R2 2 LSPVPVPR 8 0 Q9UKM9-2;Q5QPL9;Q9UKM9;Q5QPM0;Q5QPM1 Q9UKM9-2 RALY RNA-binding protein Raly 1 LS(1)PVPVPR;LS(1)PVPVPR 83.647 0.014759 30864000.0 74748.0 89117.0 109820.0 127824.0 106551.0 112820.0 113146.0 137768.0 97755.0 107629.0 True False 98516.3091450145 117922.32747208167 108363.7150448866 98356.15166111363 91758.23285413798 105765.34756507845 123215.77480715408 116479.1211936955 102922.12972921225 103860.94146971784 0.9485404980055794 1.1353866603112164 1.0433538682728156 0.9469984603383437 0.8834719920278349 1.0183361143121918 1.1863533399904662 1.1214910970902057 0.990960877811999 1.0 16.664293682652193 -7.018979299472518 24.843501842431095 1.0873283295097032 0.9950400777244043 0.18088425867062097 0.08175267673492662 1174.1762071693643 1536969.0654303818 0.03275641151424525 0.025806937866394333 9.572396967753338e-08 7.018979299472518 -0.09228825178529887 LS(ph)PVPVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSPVPVPR 8 0 Q9UKM9-2;Q5QPL9;Q9UKM9;Q5QPM0;Q5QPM1 Q9UKM9-2 RALY RNA-binding protein Raly 1 LS(1)PVPVPR;LS(1)PVPVPR 93.598 0.007104899999999999 12912900.0 52755.0 68966.0 63661.0 57439.0 68443.0 53064.0 61164.0 50382.0 46818.0 38755.0 True False 61685.37954125497 75812.48869958424 65178.91967568698 54220.879049750576 55032.085472186525 50281.23042616681 55370.103130987365 49059.525884141556 47502.62467904593 45780.974715588825 1.3474020578301615 1.6559824068964049 1.423711925764066 1.184353967703704 1.2020732589043723 1.098299691925205 1.2094566241756612 1.0716138349810267 1.0376062321554476 1.0 15.482460558965032 -5.7710197033969886 2.4857375573083056 1.1145438872741908 1.5129268761282482 0.7650972979398158 0.09296495303778184 0.1268111403671532 1.5980184735089862 0.026810794183450188 0.04871595600174045 1.694260932206037e-06 5.7710197033969886 0.3983829888540573 LS(ph)PVPVPR ddPTM_PC-9_Lapatinib_30min_R1 4 LSPVPVPR 8 0 Q9UKM9-2;Q5QPL9;Q9UKM9;Q5QPM0;Q5QPM1 Q9UKM9-2 RALY RNA-binding protein Raly 1 LS(1)PVPVPR;LS(1)PVPVPR;LS(1)PVPVPR;LS(1)PVPVPR 83.78299999999999 0.014566999999999998 30866600.0 102897.0 158469.0 177329.0 157241.0 168409.0 164127.0 159190.0 152773.0 170252.0 140020.0 True False 101429.66991100105 158102.07476680668 162749.6941297353 168805.027680599 158503.513724833 157107.6708087238 167432.07927734766 159871.39130525672 151076.42692696027 164222.27043507746 0.6176365096054349 0.9627322430017778 0.9910330291900067 1.0279058207719354 0.965176728496728 0.9566770109346022 1.0195455149521826 0.9735061565140107 0.9199509087696228 1.0 17.325290260916624 -4.761213111552187 5.313542570379558 0.9820120946953822 0.597896144722959 0.9309531750487438 0.029614059130078675 0.03745135636108732 3.1246750673548727 0.007509341675286077 0.053308699622236486 1.7329534158685365e-05 4.761213111552187 -0.38411594997242315 LS(ph)RNGAPLLR ddPTM_PC-9_Lapatinib_30min_R1 1 LSRNGAPLLR 10 1 O95696-2;O95696;J3KQ61 O95696-2 BRD1 Bromodomain-containing protein 1 1 LS(1)RNGAPLLR 89.029 0.0045344999999999995 15176000.0 29128.0 20970.0 25554.0 16875.0 21053.0 22935.0 19106.0 16151.0 30085.0 16792.0 True False 28712.62937857902 20921.445253392965 23453.048761292575 18116.04379334978 19814.703931790522 21954.123514096274 20095.215193624015 16901.434422124315 26696.510490905213 19694.474826066453 1.4579027687794277 1.0623002358865932 1.1908440803027402 0.9198541191549037 1.0061047124529028 1.114735158362237 1.0203478575131726 0.8581815240767207 1.355532997283648 1.0 14.265503326030148 -2.5166672504704444 1.3351593402901993 1.043152099372573 199.0181015322527 0.4382364138387247 0.13394038481142614 616.4862682340525 3.0588185120345215 0.03660233841302622 371763.6602215328 0.0030432157962381706 2.5166672504704444 197.97494943288012 LS(ph)SAGPR ddPTM_PC-9_AZD4547_30min_R2 1 LSSAGPR 7 0 Q6PL18;Q6PL18-2 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 LS(0.5)S(0.5)AGPR 87.181 0.018113999999999998 12795000.0 14344.0 16331.0 22031.0 28710.0 22525.0 22365.0 26236.0 22334.0 17391.0 22875.0 True False 18905.09362626546 21609.67637988901 21738.85454520032 22091.35306507832 19397.792559801972 20966.513014474207 28570.9531741334 18882.7934842634 18310.25275556983 22074.153212608115 0.8564357347790547 0.978958339726762 0.9848103497253846 1.000779185153992 0.8787559084586999 0.9498218487719268 1.2943170638960004 0.855425497068585 0.8294883422803981 1.0 14.430070475207895 -4.76096904783923 21.721473357844665 0.9775306382501753 0.8564351566682321 0.07759233947813649 0.12198543049716776 6.340030653007587 290932.6675634916 0.031098426847988997 0.17750597549150438 1.733927570340748e-05 4.76096904783923 -0.12109548158194317 LS(ph)SAGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSSAGPR 7 0 Q6PL18;Q6PL18-2 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 LS(0.5)S(0.5)AGPR 104.06 0.010406 9989000.0 16017.0 23142.0 25457.0 20655.0 30224.0 25807.0 31089.0 30815.0 22654.0 23514.0 True False 18728.361749829983 25439.384819850107 26063.991426210123 19497.76731441351 24301.824164799382 24453.63548937294 28144.024855131553 30006.138901191334 22985.27189284262 27776.902063278405 0.6742422789685115 0.9158467262438693 0.9383332729774505 0.7019417525394213 0.8748932515741868 0.8803586315588848 1.0132168371770476 1.0802550562634565 0.8274958755472442 1.0 14.761598085162163 -7.011799200265471 2.5834944779809903 0.9859280766231632 0.8256982747974048 0.36565265176379047 0.09839558151334664 0.32513591319563806 4.3552414138792495 0.04047607930338556 0.032094008555169806 9.731970856910245e-08 7.011799200265471 -0.1602298018257584 LS(ph)SAGPR ddPTM_PC-9_Lapatinib_30min_R1 2 LSSAGPR 7 0 Q6PL18;Q6PL18-2 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 LS(0.5)S(0.5)AGPR;LS(0.5)S(0.5)AGPR 104.44 0.01035 21548000.0 32451.0 47698.0 39402.0 35927.0 51611.0 55388.0 54765.0 55092.0 61405.0 44818.0 True False 31988.242789215434 47587.558211556374 36162.51965611843 38569.19142895867 48575.34245113009 53019.18435573423 57600.463732797 57651.775443234015 54488.922276683916 52564.73158376885 0.6085495316995567 0.9053134445425505 0.6879616534993367 0.7337465685997762 0.9241052125172343 1.0086455834220545 1.095800587148496 1.096776749470475 1.0366061165907148 1.0 15.681807524410605 -6.5204595751626515 2.0760134374941352 1.0617924398207734 0.7405931703366193 0.7938470525262793 0.07525667303729726 0.13822431142051794 1.1977869001418395 0.026681361861201503 0.028872162552844614 3.0167576648080595e-07 6.5204595751626515 -0.3211992694841541 LS(ph)SATANALYSSNLR ddPTM_PC-9_AZD4547_30min_R2 3 LSSATANALYSSNLR 15 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LS(0.5)S(0.5)ATANALYSSNLR;LS(0.5)S(0.5)ATANALYSSNLR;LS(0.914)S(0.085)AT(0.001)ANALYSSNLR 249.36 1.7604e-40 115000000.0 119031.0 146427.0 175859.0 178101.0 151359.0 142994.0 133201.0 150864.0 134140.0 130534.0 True False 156880.38200139426 193756.6642139495 173526.99475577072 137042.56608302039 130345.41549651789 134052.5625750826 145055.6309554714 127551.43530983754 141230.3665477624 125964.04439145737 1.2454377974230364 1.5381902442875968 1.3775914833006027 1.0879498728790764 1.034782712211467 1.0642129126823572 1.1515637788247197 1.0126019367355898 1.1211958716478014 1.0 16.942652459107777 -5.755391611636452 5.014017274737179 1.06835630618358 1.4069100704842712 0.7756830810581998 0.07875650576660294 0.0729774255886809 5.034383350652858 0.020733990218526246 0.03429562120392696 1.7563391750976882e-06 5.755391611636452 0.3385537643006913 LS(ph)SATANALYSSNLR ddPTM_PC-9_Lapatinib_30min_R1 3 LSSATANALYSSNLR 15 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LS(0.966)S(0.027)AT(0.006)ANALYSSNLR;LS(0.613)S(0.378)AT(0.008)ANALYSSNLR;LS(0.586)S(0.413)AT(0.001)ANALYSSNLR 185.86 4.0444000000000004e-07 63400000.0 32303.5 34158.8 39409.1 38934.4 92479.0 138437.0 196602.0 174075.0 134628.0 166690.0 True False 31842.84616626363 34079.7073973104 36169.03592152522 41797.76565735097 87039.56704070944 132516.37222240894 206781.08957902578 182163.15999203053 119464.77694431067 195502.14439953637 0.16287722195613494 0.17431884188269403 0.18500582708498922 0.21379696773008947 0.4452102932581227 0.6778256710657502 1.0576921814035927 0.9317706491226729 0.6110663251865281 1.0 17.576824906509643 -6.680811806664651 1.7886407326289486 0.8945507520353604 0.1785397946138549 0.887538273348705 0.11491117134131959 0.10948841907441721 0.7220833217736533 0.04720750907716721 0.04579836404291458 2.0853943537043962e-07 6.680811806664651 -0.7160109574215054 down LS(ph)SDLTR ddPTM_PC-9_AZD4547_30min_R2 2 LSSDLTR 7 0 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;Q7Z6E9-4 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 LS(0.953)S(0.046)DLTR;LS(0.996)S(0.003)DLTR 99.13600000000001 0.011939 12352800.0 67318.0 80925.0 75953.0 90190.0 83971.0 106252.0 89083.0 112839.0 85420.0 74360.0 True False 88723.72369861546 107082.42367537317 74945.81359319146 69398.08892160958 72313.0760949671 99608.0456433674 97011.2144233623 95402.32533226442 89935.12681161384 71756.67903342254 1.2364524793195917 1.4922990461347403 1.0444437312697192 0.9671307236680452 1.0077539410831067 1.3881362262734087 1.351946825440135 1.3295253712595632 1.2533345748863909 1.0 16.13082550206861 -6.773888777384265 24.99986959510951 1.290643799693609 1.1526729364401649 0.09258921191235703 0.17033683788707318 523.0183074231815 1050276.5414147687 0.06414788690738556 0.0569612172944586 1.6831050483038817e-07 6.773888777384265 -0.1379708632534442 LS(ph)SDLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSSDLTR 7 0 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;Q7Z6E9-4 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 LS(0.953)S(0.046)DLT(0.001)R 88.177 0.017446 3146300.0 21602.0 37747.0 30387.0 32340.0 35544.0 23790.0 41550.0 19487.0 21537.0 30138.0 True False 25258.791941051848 41494.27269876769 31111.541323339236 30528.094647694634 28579.408354738924 22542.410520098525 37614.08320405018 18975.48689818321 21851.93788099902 35601.780827723254 0.709481137004886 1.1655111551738986 0.8738759859763124 0.8574878542008854 0.8027522132399629 0.6331821048273141 1.0565225202094366 0.5329926328687166 0.6137877761435694 1.0 15.119661787231783 -6.025978872845662 1.8549193455626618 0.7549283186877634 0.9439921024405619 0.10491147907887466 0.18542674833482217 0.6580583670287724 4.537290046573077 0.05995910190988549 0.09519261454459518 9.419354178071018e-07 6.025978872845662 0.18906378375279842 LS(ph)SDLTR ddPTM_PC-9_Lapatinib_30min_R1 2 LSSDLTR 7 0 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;Q7Z6E9-4 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 LS(0.963)S(0.036)DLTR;LS(0.995)S(0.005)DLTR 96.66799999999999 0.012731000000000001 12094400.0 42917.0 61802.0 73179.0 55449.0 90399.0 87617.0 123160.0 121040.0 97187.0 95145.0 True False 42304.99570998611 61658.90126610352 67162.505099109 59526.904432441544 85081.90855127216 83869.8251552027 129536.62217349178 126663.96027824443 86240.77663551956 111590.68647725647 0.37910866081649547 0.5525452276760602 0.6018647901480337 0.5334397189551643 0.7624463226921082 0.7515844538898538 1.1608192965090587 1.1350764501664758 0.772831311984952 1.0 16.76785709717938 -6.687771457949235 1.3564807194240764 1.0224181746975651 0.5138777411234544 0.7534013047488558 0.12398623354140662 0.2066454550879018 0.7956355513504105 0.05721241263237776 0.055165397605758136 2.0522418613818763e-07 6.687771457949235 -0.5085404335741107 LS(ph)SDSFAR ddPTM_PC-9_AZD4547_30min_R2 2 LSSDSFAR 8 0 A0A087WSV0;Q9HB09;Q9HB09-3 A0A087WSV0 BCL2L12 Bcl-2-like protein 12 1 LS(0.952)S(0.048)DSFAR;LS(0.965)S(0.034)DS(0.001)FAR 125.57 0.0034478 40880000.0 110809.0 153678.0 158142.0 208707.0 198530.0 168039.0 181473.0 216084.0 137891.0 169440.0 True False 146043.95702961838 203351.408162916 156044.93375185286 160592.82564100652 170967.53637724728 157531.49476589452 197623.74544021615 182693.18291634182 145179.63674994407 163507.9571735221 0.8931917415776278 1.243678972437471 0.9543568181593197 0.9821713170239055 1.0456221173126683 0.9634484919820441 1.2086491009761 1.1173351197976225 0.8879056362735473 1.0 17.319001321141464 -8.263711348528162 24.94580790436212 0.9439528227475941 1.0541095947056065 0.13275756769922054 0.10927525639036191 403.7523764847717 4432965.190146777 0.08787127459552853 0.026847017998704686 5.4486467387164876e-09 8.263711348528162 0.11015677195801243 LS(ph)SDSFAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSSDSFAR 8 0 A0A087WSV0;Q9HB09;Q9HB09-3 A0A087WSV0 BCL2L12 Bcl-2-like protein 12 1 LS(0.95)S(0.047)DS(0.002)FAR;LS(0.654)S(0.331)DS(0.016)FAR 104.42 0.0038583 18202300.0 77708.0 109839.0 103654.0 80177.0 140997.0 76359.0 94700.0 110378.0 92624.0 63466.0 True False 90862.42959704009 120743.09001933814 106125.50446998425 75684.94262734104 113369.6500054336 72354.59961766301 85729.33043137327 107480.6944551579 93978.45077260752 74971.88340342052 1.2119534080278231 1.610511628334381 1.4155373941845295 1.0095110218864793 1.5121622248089506 0.9650897954413922 1.1434864183692355 1.4336133704526115 1.2535159383273522 1.0 16.194062024761045 -5.6049808840003426 12.11888260472671 1.2086835523106019 1.4366473203467793 0.21441383104861633 0.19293196805039547 0.833467437824105 118.9148773295049 0.05064595919714241 0.08773710660918836 2.483242405823795e-06 5.6049808840003426 0.22796376803617746 LS(ph)SDSFAR ddPTM_PC-9_Lapatinib_30min_R1 3 LSSDSFAR 8 0 A0A087WSV0;Q9HB09;Q9HB09-3 A0A087WSV0 BCL2L12 Bcl-2-like protein 12 1 LS(0.766)S(0.222)DS(0.012)FAR;LS(0.966)S(0.033)DS(0.001)FAR;LS(0.958)S(0.042)DS(0.001)FAR 125.71 0.0034603999999999998 36618600.0 175998.0 261837.0 165614.0 133340.0 185033.0 137432.0 122062.0 130524.0 192052.0 102837.0 True False 173488.23624591983 261230.7325137178 151997.85620852746 143146.26840920077 174149.72272887462 131554.35372963946 128381.77310604716 136588.62154128889 170421.0813627832 120612.23842831065 1.4383966213265957 2.1658725177295155 1.2602191799870437 1.1868303770374335 1.4438810273170206 1.0907214346065932 1.064417465250465 1.1324607131180495 1.4129667402207935 1.0 16.880016778225517 -5.381424442850816 7.137978416535739 1.1993041663200625 1.798850809370115 0.5677641783877803 0.21102654129334666 0.15789312870536742 8.512429185445008 0.052297603950615924 0.1096811041811264 4.155043330538675e-06 5.381424442850816 0.5995466430500525 LS(ph)SERPSSDGEGVVENGITTCNGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSSERPSSDGEGVVENGITTCNGK 24 1 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 LS(0.302)S(0.302)ERPS(0.283)S(0.114)DGEGVVENGITTCNGK;LS(0.289)S(0.256)ERPS(0.227)S(0.227)DGEGVVENGITTCNGK 75.112 0.00013427 37310000.0 40538.0 48054.0 54686.0 47924.0 59556.0 52234.0 62270.0 55588.0 51090.0 37435.0 True False 47400.28273800383 52824.48354217771 55989.92163780988 45238.973651704306 47886.429326323196 49494.75708729828 56371.334804240796 54128.87390035448 51837.09459721592 44221.66916470305 1.0718790953245585 1.1945384364718026 1.2661195901329756 1.0230046605254162 1.082872497371612 1.1192421729481916 1.2747446188493352 1.2240350697471905 1.172210266513218 1.0 15.432465860836372 LS(ph)SFTQHHR ddPTM_PC-9_Lapatinib_30min_R1 1 LSSFTQHHR 9 0 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 LS(0.883)S(0.11)FT(0.007)QHHR 88.948 0.0074843999999999996 0.0 537.87 760.85 415.96 870.69 1092.1 428.72 471.32 742.72 676.35 754.5 True False 530.1998751667224 759.0882985714844 381.76137445203346 934.723447136694 1027.8648251512107 410.38464499513225 495.7226434135287 777.2294826326649 600.1723407187551 884.9143196919443 0.5991539105744104 0.8578099389732303 0.4314105512327249 1.0562869492970677 1.1615416343460576 0.46375636133676196 0.5601928145835625 0.8783104367700066 0.678226498727794 1.0 9.789393965264676 -3.9617916190602678 1.0855131303648071 0.783390787351523 1.9814864662060444e-13 0.04552105923818983 0.2388391436705946 39.19880415684178 10.276207622034816 0.07652728288397881 54.120161957250396 0.0001091964151382194 3.9617916190602678 -0.7833907873513248 LS(ph)SGFDDIDLPSAVK ddPTM_PC-9_AZD4547_30min_R2 2 LSSGFDDIDLPSAVK 15 0 Q9Y446;Q9Y446-2;E9PKC4 Q9Y446 PKP3 Plakophilin-3 1 LS(0.526)S(0.474)GFDDIDLPSAVK;LS(0.5)S(0.5)GFDDIDLPSAVK 210.02 2.9851999999999997e-13 58574000.0 103178.0 108935.0 120615.0 152850.0 150002.0 146631.0 129739.0 170586.0 145830.0 137546.0 True False 135986.4577642788 144146.10840996925 119015.56629155915 117612.79400895927 129176.8115229931 137462.14039013512 141285.51966225382 144225.85337631215 153538.27608215433 132730.55640574385 1.0245301567830545 1.0860054558147803 0.896670439079157 0.8861018682798925 0.9732258721805753 1.03564803849633 1.064453608032489 1.0866062591904486 1.1567666122999094 1.0 17.018141011688407 -7.021363226125449 2.273385348133049 1.085758395930659 0.9706330202473243 0.36353832758285964 0.064544947314863 0.3535949776092217 3.6513300163099136 0.03014252434028994 0.023420446500102447 9.519996174636782e-08 7.021363226125449 -0.11512537568333459 LS(ph)SGFDDIDLPSAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSSGFDDIDLPSAVK 15 0 Q9Y446;Q9Y446-2;E9PKC4 Q9Y446 PKP3 Plakophilin-3 1 LS(0.5)S(0.5)GFDDIDLPSAVK;LS(0.5)S(0.5)GFDDIDLPSAVK 334.79 1.7206999999999994e-181 64116000.0 118012.0 118754.0 116784.0 122972.0 150164.0 117445.0 129518.0 128343.0 103031.0 102676.0 True False 137989.10075675425 130543.11230215534 119568.5734657865 116082.27752060305 120740.4421612934 111285.9774498937 117249.11741088287 124974.1322406491 104537.6334594979 121290.3460172314 1.137675876834835 1.076286090268136 0.985804537558164 0.9570611456917729 0.9954662190850715 0.9175171899838064 0.9666813663325324 1.0303716358669992 0.8618792582605587 1.0 16.88810519960807 -5.098294135896092 1.7589323238074117 0.9615069658398676 1.1512613599949189 0.6432821027640407 0.043989060827435145 0.3052722154765096 1.454467563089331 0.011844178872284268 0.0788022017002476 7.974544100465014e-06 5.098294135896092 0.18975439415505124 LS(ph)SGFDDIDLPSAVK ddPTM_PC-9_Lapatinib_30min_R1 4 LSSGFDDIDLPSAVK 15 0 Q9Y446;Q9Y446-2;E9PKC4 Q9Y446 PKP3 Plakophilin-3 1 LS(0.988)S(0.012)GFDDIDLPSAVK;LS(0.5)S(0.5)GFDDIDLPSAVK;LS(0.5)S(0.5)GFDDIDLPSAVK;LS(0.5)S(0.5)GFDDIDLPSAVK 268.5 8.321399999999998e-62 89103700.0 153261.3 154329.2 155176.0 148395.4 164663.9 148960.9 135999.4 146524.1 154424.2 148083.9 True False 151075.76575731984 153971.8602193581 142418.02827668196 159308.8927485429 154978.6931436833 142590.18955181804 143040.78348182494 153332.1445985251 137031.32043708314 173680.00480560618 0.8698512297164751 0.8865261167610704 0.8200024432063171 0.9172552299664641 0.892323173972418 0.8209936987934456 0.8235880903039206 0.8828428164206024 0.7889873137121189 1.0 17.406072145420886 -6.729408572367251 24.998632543864517 0.8534790861147505 0.8767587902041221 6.540036658020387e-05 0.05803893735280383 788.6983683804062 615542.3441473691 0.018021834347484132 0.018020164275743423 1.8646246775451833e-07 6.729408572367251 0.023279704089371522 LS(ph)SPGPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSSPGPSR 8 0 Q86VQ6;H0YBI6;H0YBQ0 Q86VQ6 TXNRD3 Thioredoxin reductase 3 1 LS(0.874)S(0.126)PGPSR 71.61399999999999 0.03493 4318600.0 21875.0 26993.0 26499.0 34613.0 33184.0 30887.0 31152.0 22186.0 23846.0 25067.0 True False 25578.005449056058 29672.686649477735 27130.83665801714 32673.745826860086 26681.833413337183 29267.23134654406 28201.057039051073 21603.6410080101 24194.70263780017 29611.44866973718 0.8637877104336578 1.002068050787503 0.916227941449713 1.1034159858667287 0.9010647777123428 0.9883755324829849 0.9523700563786491 0.729570553908393 0.8170725758016388 1.0 14.853867452216926 -7.631663814313974 8.924154572505246 0.8303842375490383 0.9661422514385437 0.2480491469365188 0.08772497254880954 0.29738421395470843 22.507291209265393 0.039128915470624984 0.022521162280751073 2.33526508249461e-08 7.631663814313974 0.13575801388950537 LS(ph)SPISK ddPTM_PC-9_AZD4547_30min_R2 1 LSSPISK 7 0 A0A494C142;Q99728-3;Q99728-2;Q99728 A0A494C142 BARD1 BRCA1-associated RING domain protein 1 1 LS(0.499)S(0.499)PIS(0.001)K 76.1 0.031751 25185000.0 204250.0 258480.0 294710.0 307450.0 283720.0 301730.0 278000.0 357080.0 296750.0 298400.0 True False 269197.25133607944 342028.6051481051 290801.95283990685 236572.15255514867 244330.37536368557 282862.7754016231 302741.4614426397 301901.4908820977 312435.5991728681 287953.1068258919 0.9348648962445368 1.1877927240247124 1.0098934373218535 0.8215648553435813 0.8485075158831942 0.9823223597745497 1.051356815627933 1.0484397762189785 1.085022497645005 1.0 18.13547436229173 -10.197455442126483 10.116603189987536 1.000041881887825 0.9958580034837599 4.34740390605759e-05 0.10335610314090282 0.0 0.0 0.10982328402724673 0.026636058835091014 6.346650131894919e-11 10.197455442126483 -0.004183878404065089 LS(ph)SPVK ddPTM_PC-9_AZD4547_30min_R2 1 LSSPVK 6 0 P26358;P26358-2;P26358-3 P26358 DNMT1 DNA (cytosine-5)-methyltransferase 1 1 LS(0.794)S(0.206)PVK 90.37 0.037231 170530000.0 516070.0 637300.0 556680.0 522080.0 526100.0 602740.0 594320.0 633100.0 609730.0 610000.0 True False 680169.5250771637 843294.76191925 549298.05947175 401722.52205559326 453060.0961470289 565050.572517066 647213.3286496025 535268.9421907038 641959.0830115337 588644.0856695488 1.155485193236096 1.4326055123106363 0.933158206876325 0.6824540190506747 0.769667286526287 0.9599188818390207 1.0994985669709643 0.9093252700940097 1.0905725524810839 1.0 19.1670360693741 -5.277391756757503 23.450989975402674 0.9198088181208874 1.2940453019483908 0.5294296554582185 0.13676762896774616 243.9643591806073 358643.3530263195 0.038186445059759294 0.08000310593455623 5.2796878094119635e-06 5.277391756757503 0.3742364838275034 LS(ph)SPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSSPVK 6 0 P26358;P26358-2;P26358-3 P26358 DNMT1 DNA (cytosine-5)-methyltransferase 1 1 LS(0.5)S(0.5)PVK 86.794 0.040287 129090000.0 169160.0 236620.0 199410.0 177260.0 206250.0 134250.0 207720.0 175920.0 136360.0 139340.0 True False 197795.44693770655 260110.06983289815 204164.69066663604 167328.696884674 165836.79307801326 127209.6936663821 188043.25783743203 171302.28640264765 138354.00703222465 164601.23898516662 1.2016643869584196 1.5802436934046318 1.2403593795854402 1.016570093374286 1.007506347464116 0.7728355779742694 1.1424170255144794 1.040710795731525 0.8405404958385077 1.0 17.32861566968012 -5.663317290495887 3.0347937979408997 0.9724351791647559 1.3962245591653917 0.638358855546278 0.129452557089072 0.1467422215906243 2.692056757067405 0.035768964992437764 0.06741191134877912 2.1711144083683306e-06 5.663317290495887 0.4237893800006358 LS(ph)SPVLHR ddPTM_PC-9_AZD4547_30min_R2 4 LSSPVLHR 8 0 Q16643-3;Q16643;Q16643-2;D6R9W4;D6RCR4 Q16643-3 DBN1 Drebrin 1 LS(0.5)S(0.5)PVLHR;LS(0.5)S(0.5)PVLHR;LS(0.645)S(0.355)PVLHR;LS(0.624)S(0.376)PVLHR 118.71 0.0019785000000000002 1768710000.0 704281.1 666739.1 1101226.9 1405512.0 1334412.0 1045230.7 885472.6 1156307.0 896341.9 1028604.9 True False 928227.8398430878 882249.4752812715 1086623.9117771252 1081492.9233439344 1149151.9274277673 979872.259095818 964277.9460122802 977626.3224414856 943720.7029157444 992593.7555339627 0.9351538176298022 0.8888323852155086 1.0947317628374351 1.0895624895022118 1.1577263316648456 0.9871835820372442 0.9714729118898696 0.9849208873126293 0.9507622807964098 1.0 19.920843853020543 -10.47498505375409 14.113431477583546 0.9999976804896519 1.0104549910916945 0.0 0.0786054160993838 0.0 0.0 0.08408598594343687 0.020393847157587776 3.349769671927987e-11 10.47498505375409 0.01045731060204258 LS(ph)SPVLHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LSSPVLHR 8 0 Q16643-3;Q16643;Q16643-2;D6R9W4;D6RCR4 Q16643-3 DBN1 Drebrin 1 LS(0.5)S(0.5)PVLHR;LS(0.5)S(0.5)PVLHR;LS(0.64)S(0.36)PVLHR;LS(0.643)S(0.357)PVLHR;LS(0.643)S(0.357)PVLHR 111.06 0.0021264 1790570000.0 627249.9 647074.5 853897.9 793222.0 967323.0 852309.0 833457.0 767103.8 806869.3 687055.7 True False 733430.9193197645 711311.7799936099 874258.0643618193 748780.3430004228 777783.0021362565 807612.4156357573 754505.9192538641 746968.1380636593 818668.2370657536 811613.4596800719 0.9036702269684808 0.8764169340833754 1.077185270814066 0.9225824609852858 0.9583170323996957 0.9950702591281669 0.929637021484687 0.9203496185956613 1.0086922873216797 1.0 19.63043326517539 LS(ph)SPVLHR ddPTM_PC-9_Lapatinib_30min_R1 3 LSSPVLHR 8 0 Q16643-3;Q16643;Q16643-2;D6R9W4;D6RCR4 Q16643-3 DBN1 Drebrin 1 LS(0.5)S(0.5)PVLHR;LS(0.566)S(0.434)PVLHR;LS(0.648)S(0.352)PVLHR 131.5 0.0022485 1131916300.0 653547.0 535880.0 658134.0 532621.9 593445.0 592546.3 483842.0 529504.3 585523.8 430258.6 True False 644227.299934157 534639.2027843692 604024.7629907066 571792.6913005727 558539.73185776 567204.4760418906 508892.971302912 554107.0028284838 519575.9438050416 504628.22572645155 1.27663746713086 1.0594714594387076 1.196969832833203 1.1330969259149797 1.106834107532726 1.1240046575384395 1.0084512624523152 1.0980499595138653 1.0296212485083878 1.0 18.944861378287122 -1.5228787453157564 0.14372898852166252 0.9695506986106054 1.8190419079639772 0.5746303053301298 0.05346208151175166 54.10557368887417 0.5168444907193548 0.20389371284314098 9.48976718367963 0.029999999997553352 1.5228787453157564 0.8494912093533719 LS(ph)SSGSNCSSGSEGEPVALHAGICVR ddPTM_PC-9_AZD4547_30min_R2 2 LSSSGSNCSSGSEGEPVALHAGICVR 26 0 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 LS(0.427)S(0.427)S(0.12)GS(0.023)NCS(0.001)S(0.001)GSEGEPVALHAGICVR;LS(0.715)S(0.232)S(0.035)GS(0.01)NCS(0.005)S(0.002)GSEGEPVALHAGICVR 79.286 2.437e-05 11041500.0 14227.0 19275.4 23677.0 38705.0 31512.0 32949.0 19598.2 30223.0 25188.4 25398.6 True False 18750.890060016634 25505.796099008774 23363.02750972302 29782.160236288946 27137.102736713852 30888.693821323974 21342.401833255884 25552.729805448773 26519.80740086223 24509.40274473217 0.7650488367794592 1.0406535142718139 0.9532271248325076 1.2151320269397448 1.1072119145190698 1.2602793361810054 0.8707842478064067 1.0425684408381124 1.0820258525704858 1.0 14.581047707992816 -4.243876221917048 1.414871243381202 1.0766901647379792 7.151836663357979e-19 0.40464888720145187 0.10869529506995448 5.007927182873864 3.165920775944873 0.03140117240022649 11.150078189692923 5.7032679771359894e-05 4.243876221917048 -1.0766901647379792 LS(ph)SSLGR ddPTM_PC-9_AZD4547_30min_R2 3 LSSSLGR 7 0 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 LS(0.925)S(0.038)S(0.038)LGR;LS(0.481)S(0.26)S(0.26)LGR;LS(0.391)S(0.218)S(0.391)LGR 101.6 0.011146 615548000.0 119448.0 100311.0 187037.0 238367.0 200878.0 187058.0 163190.0 205819.0 150752.0 172640.0 True False 157429.97932725598 132734.5690614811 184556.76717219505 183415.17088343858 172989.5571066773 175361.2336893143 177713.5938590806 174014.40280010828 158720.4429536922 166595.92614752616 0.9449809666284791 0.7967455875478029 1.1078108057021994 1.1009583194790635 1.038378075064629 1.0526141769758894 1.0667343311967268 1.0445297602656431 0.9527270361529732 1.0 17.345993596637143 -5.264575738687264 24.999985596461993 1.0498025792067565 0.8708632737734104 0.6238128807437289 0.05415312619838786 150.63524979502392 1200726.525744002 0.01382940376275112 0.030895458632464116 5.437812908363981e-06 5.264575738687264 -0.17893930543334602 LS(ph)SSLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LSSSLGR 7 0 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 LS(0.819)S(0.091)S(0.091)LGR;LS(0.567)S(0.285)S(0.148)LGR;LS(0.817)S(0.041)S(0.142)LGR;LS(0.464)S(0.268)S(0.268)LGR 108.09 0.0098116 400941500.0 220486.0 218355.0 240374.0 267586.0 295080.0 250711.0 265231.0 246527.0 231177.0 194728.0 True False 257809.92500299713 240031.84134207788 246105.4277834715 252594.0239455165 237261.19224950334 237563.2738085089 240106.39957384902 240055.92746694767 234557.52628108414 230030.64493399963 1.1207633881866823 1.0434776697293866 1.0698810493448994 1.0980885786673804 1.031432974148198 1.0327461972585024 1.0438017927686998 1.0435823780602123 1.0196794707434889 1.0 17.81146654582055 -1.522878745280338 0.12878621285542097 0.984806211836565 1.3507073026386351 0.6274235578723004 0.02105443359015149 60.352211818018176 0.5290102843597422 0.11875214550419347 4.001801701089018 0.029999999999999964 1.522878745280338 0.3659010908020701 LS(ph)STSSEETQLFHIPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSSTSSEETQLFHIPR 16 0 Q8N271-3;Q8N271-2;Q8N271 Q8N271-3 PROM2 Prominin-2 1 LS(0.652)S(0.13)T(0.13)S(0.034)S(0.054)EETQLFHIPR;LS(0.309)S(0.309)T(0.309)S(0.037)S(0.037)EETQLFHIPR 86.573 0.0025231999999999997 3980000.0 14682.6 21754.0 21224.0 27456.0 24465.0 27737.0 21927.0 18577.800000000003 26276.0 21258.5 True False 17168.07418543134 23913.593352822558 21730.060652468233 25917.729333552994 19671.258873471983 26282.422891802118 19849.915822267365 18090.15243480619 26660.236790691837 25112.497767806595 0.6836466186744773 0.9522586551895689 0.8653086145945014 1.0320649731138525 0.7833254603088465 1.0465873659726246 0.7904397247060908 0.7203645213658187 1.0616322214220122 1.0 14.616117910270107 -4.754110790849921 24.979766063715196 0.9060636045687105 0.6836462238316717 0.2614016627399751 0.1163449883763795 368.6628898741878 1256494.053324606 0.027632648638052412 0.27815569095236004 1.7615266142076527e-05 4.754110790849921 -0.22241738073703876 LS(ph)SYTECYK ddPTM_PC-9_AZD4547_30min_R2 1 LSSYTECYK 9 0 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1;Q8IWC1-3 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 1 LS(0.621)S(0.372)YT(0.008)ECYK 110.54 0.0022949999999999997 12357000.0 66049.0 54154.0 80592.0 95932.0 73854.0 60985.0 65143.0 60626.0 59484.0 60809.0 True False 87051.20809545503 71658.22146081123 79523.29742212263 73816.35953462537 63600.64691283522 57171.59830930962 70940.60080128726 51257.644746886035 62628.20280100718 58680.095418819066 1.4834878415609594 1.2211674324890411 1.3552005472134767 1.2579454584689038 1.0838538427536044 0.9742928654300439 1.2089380614493033 0.8735099079345975 1.067281884155252 1.0 15.84058359650733 -6.209052087758398 2.158405108514725 1.0262005264788223 1.342181257951802 0.6906680613272577 0.09863052724014015 0.18290861553326598 1.6727283701884494 0.031650141444755454 0.04235163060814576 6.179422818617362e-07 6.209052087758398 0.31598073147297967 LS(ph)TGSFPEDLLESDSSR ddPTM_PC-9_AZD4547_30min_R2 7 LSTGSFPEDLLESDSSR 17 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 LS(0.969)T(0.021)GS(0.01)FPEDLLESDSSR;LS(0.999)T(0.001)GSFPEDLLESDSSR;LS(0.914)T(0.086)GSFPEDLLESDSSR;LS(0.838)T(0.15)GS(0.011)FPEDLLESDSSR;LS(0.735)T(0.112)GS(0.153)FPEDLLESDSSR;LS(0.965)T(0.024)GS(0.011)FPEDLLESDSSR;LS(0.976)T(0.023)GSFPEDLLESDSSR 188.44 4.2725e-42 3109300.0 20733.6 23937.74 27592.0 30603.8 28209.859999999997 32867.299999999996 29263.420000000002 35007.4 29584.199999999997 26653.699999999997 True False 27326.453514329154 31675.146326980852 27226.112051707474 23548.566733996628 24293.407876628426 30812.102535239366 31867.807689243775 29597.810720023386 31147.960414658643 25720.56207575488 1.0624360942752509 1.2315106580364734 1.058534878495979 0.9155541260972033 0.9445131022050354 1.1979560339501272 1.2390012160458774 1.150745097748985 1.211013986510809 1.0 14.650634550016386 -6.786446940818991 24.999060733275726 1.1741184998552026 1.0468469760269423 0.2509486445061957 0.09959578885624754 331.5812800340784 331466.08534124284 0.03758920585166613 0.03316350767122659 1.635132908476492e-07 6.786446940818991 -0.12727152382826024 LS(ph)TGSFPEDLLESDSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LSTGSFPEDLLESDSSR 17 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 LS(0.981)T(0.007)GS(0.012)FPEDLLESDSSR;LS(0.497)T(0.497)GS(0.007)FPEDLLESDSSR;LS(0.438)T(0.438)GS(0.124)FPEDLLESDSSR;LS(0.581)T(0.085)GS(0.334)FPEDLLESDSSR 132.4 2.4094e-05 1014100.0 9264.48 13378.400000000001 9092.24 12823.6 15700.8 10240.9 14130.1 9927.27 8082.12 9890.74 True False 10832.773482179238 14706.519137234576 9309.033484112217 12105.135266672134 12624.340949135865 9703.849175925896 12791.59463493501 9666.689681312018 8200.305715131159 11683.852866945235 0.9271576427349763 1.258704581845665 0.796743470678956 1.0360568045938636 1.0804946872321 0.8305350372375054 1.094809630059934 0.8273546227768779 0.7018494505635745 1.0 13.512228475295373 -7.78298650029577 23.995342103694377 0.823451231875763 1.0029245963833533 0.20516182243633196 0.14315106635615046 216.9789473427809 241627.09264322618 0.07414921693785266 0.03568172969756061 1.648213624160382e-08 7.78298650029577 0.17947336450759033 LS(ph)TGSFPEDLLESDSSR ddPTM_PC-9_Lapatinib_30min_R1 3 LSTGSFPEDLLESDSSR 17 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 LS(0.499)T(0.499)GS(0.003)FPEDLLESDSSR;LS(0.774)T(0.225)GS(0.001)FPEDLLESDSSR;LS(0.943)T(0.048)GS(0.009)FPEDLLESDSSR 147.83 1.1825e-11 0.0 7903.7 11228.7 9789.6 10441.0 12621.1 14387.300000000001 13199.400000000001 13630.5 15512.7 12179.399999999998 True False 7790.991788638933 11202.70063503927 8984.736876948806 11208.865970154968 11878.751712037309 13771.988717434375 13882.800346839787 14263.822790586672 13765.496370027106 14284.593061969612 0.5454122322449053 0.7842505968801187 0.6289809473725363 0.7846822042132048 0.8315778867836662 0.9641148794150838 0.9718723023199357 0.9985459668824422 0.9636603794248423 1.0 13.802172317059943 -6.322793650455993 1.0250475744227348 0.9931040868155833 0.6469930851508757 0.8567134418196726 0.058131389061023886 0.179680820872859 0.3993327133712316 0.025280814876786926 0.036455323182971976 4.7556112914184935e-07 6.322793650455993 -0.34611100166470754 LS(ph)TGTTVEDVQK ddPTM_PC-9_AZD4547_30min_R2 4 LSTGTTVEDVQK 12 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 LS(0.869)T(0.131)GTTVEDVQK;LS(0.871)T(0.128)GTTVEDVQK;LS(0.685)T(0.314)GTT(0.001)VEDVQK;LS(0.838)T(0.132)GT(0.023)T(0.006)VEDVQK 189.99 0.00018472 94111000.0 248491.0 283427.0 357315.0 296025.0 268703.0 349809.0 335138.0 336002.0 313860.0 276900.0 True False 327505.96906611323 375039.235032931 352576.7696345264 227781.00979065866 231398.22660139672 327935.38793115225 364964.63275166636 284080.6114578433 330449.9988421104 267205.8152818005 1.2256693168175212 1.403559404713581 1.3194951212521029 0.8524552863882708 0.8659924798319213 1.2272763883724054 1.3658558754298347 1.0631528028618924 1.2366871525367489 1.0 18.02759188040342 -5.583298857732233 24.994943607912813 1.0972489763293416 1.326345829970946 0.3049470728253868 0.1576771784313545 91.61201259112711 37897.86272282916 0.04664913442623154 0.0807986768539994 2.6103644260306545e-06 5.583298857732233 0.22909685364160448 LS(ph)TGTTVEDVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSTGTTVEDVQK 12 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 LS(0.86)T(0.139)GT(0.001)TVEDVQK;LS(0.655)T(0.338)GT(0.008)TVEDVQK 182.37 6.1818e-05 25083000.0 39388.0 57634.0 56357.0 68736.0 123136.0 127306.0 205433.0 197080.0 175478.0 137619.0 True False 46055.610451539185 63355.52263016341 57700.76461511268 64884.9447651187 99008.3847391721 120629.84925059535 185972.89903387826 191906.8588235207 178044.0337782398 162568.2353085951 0.2833001807771004 0.38971649356898547 0.35493258880237105 0.39912437163355363 0.6090266315017167 0.7420259500363634 1.1439682462004663 1.1804695945627606 1.095195709298731 1.0 17.31068586690764 -6.847865379121829 1.3736015231030585 1.1330740887168604 0.35186043167893843 0.957344435825827 0.07033573995870912 0.07454440479100133 0.29256274467276827 0.034125015932099524 0.02856386660110387 1.4194974636843646e-07 6.847865379121829 -0.781213657037922 down LS(ph)TGTTVEDVQK ddPTM_PC-9_Lapatinib_30min_R1 4 LSTGTTVEDVQK 12 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 LS(0.862)T(0.138)GTTVEDVQK;LS(0.985)T(0.015)GTTVEDVQK;LS(0.863)T(0.136)GT(0.001)TVEDVQK;LS(0.842)T(0.157)GT(0.001)TVEDVQK 195.71 1.3749000000000002e-05 71510000.0 102611.0 127843.0 138111.0 138068.0 300727.0 382949.0 460275.0 439905.0 420261.0 440810.0 True False 101147.74832344701 127546.98738815081 126756.04670387751 148221.9813013465 283038.82911203004 366571.1639677204 484105.78735712834 460344.5922521567 372926.78063547704 517003.4211575947 0.19564231914940233 0.24670433921417226 0.24517448341069933 0.28669439163375476 0.5474602633736793 0.7090304415141984 0.9363686342214003 0.890409179926554 0.7213236225796662 1.0 18.979814301728986 -6.573121460232249 1.4107473563998418 0.881153413108956 0.2223082669355516 0.9435269209555008 0.071067696641417 0.08692849865346862 0.35794355217395096 0.029982608377871606 0.03190751039965037 2.6722589467517237e-07 6.573121460232249 -0.6588451461734044 down LS(ph)TIQNSPTK ddPTM_PC-9_AZD4547_30min_R2 1 LSTIQNSPTK 10 0 Q5VYV7 Q5VYV7 SLX4IP Protein SLX4IP 1 LS(0.415)T(0.415)IQNS(0.049)PT(0.12)K 116.03 0.001075 18299000.0 33444.0 28153.0 33667.0 44640.0 47688.0 36913.0 39485.0 35996.0 35829.0 34446.0 True False 44078.496321585466 37252.90668807881 33220.553582372995 34348.93768112491 41067.3443547985 34604.824274683044 42999.08850741948 30433.64530579142 37722.84779364677 33240.05602454641 1.326065644685897 1.1207233423604663 0.9994132849186833 1.033359801071323 1.235477591387691 1.0410579407305696 1.293592540146937 0.9155714203164227 1.1348611375922473 1.0 15.020635193254192 LS(ph)VDYGKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSVDYGKK 8 1 Q9BQE3;F5H5D3;P0DPH8;P0DPH7;P0DPH7-2;F8VQQ4;C9JDS9;P68363;P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8;Q71U36-2;Q71U36 Q9BQE3;P68363;P68366-2;Q71U36-2 TUBA1C;TUBA1A;TUBA4A;TUBA1B Tubulin alpha-1C chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain;Tubulin alpha-1A chain 1 LS(1)VDYGKK 83.31 0.022382 6476100.0 36426.0 30846.0 35884.0 42158.0 40499.0 37031.0 35649.0 34996.0 28776.0 30562.0 True False 42592.20235370586 33908.187025887855 36739.61065082783 39796.02393808013 32563.511674504032 35089.029170650225 32272.068643590523 34077.392081327016 29196.794561156494 36102.64867134112 1.1797528414450171 0.9392160485112754 1.0176430816831548 1.1023020582329426 0.9019701565650912 0.971923957438183 0.8938975347038353 0.9439028252898856 0.8087161367839859 1.0 15.139817063887193 -6.272017632419325 24.539975943912168 0.918547800907654 1.048114373399533 0.451819286671192 0.07491604811251475 538.335239755624 1248854.9424122756 0.022368096339439127 0.02564961279111585 5.345426564465665e-07 6.272017632419325 0.12956657249187908 LSAMLVPVT(ph)PEVKPK ddPTM_PC-9_AZD4547_30min_R2 1 LSAMLVPVTPEVKPK 15 1 Q5JSK7;Q5JSK8;Q5JSL0;Q5JSK6;P82970 Q5JSK7 HMGN5 High mobility group nucleosome-binding domain-containing protein 5 1 LS(0.002)AMLVPVT(0.998)PEVKPK 62.94 0.026608999999999997 4685900.0 33399.0 35001.0 38810.0 53499.0 44399.0 46449.0 37586.0 45290.0 47312.0 44740.0 True False 44019.18725764362 46314.388768140016 38295.354041996485 41165.6321013105 38234.96523252597 43544.53668720377 40931.08118626993 38291.47116066486 49812.81573063768 43173.66621779616 1.019584184386429 1.0727462554257032 0.8870072291014091 0.9534893769188878 0.8856084873506882 1.0085902009696535 0.9480566459143597 0.8869172927658652 1.153777756082824 1.0 15.397863988208247 -10.270273389017373 6.2108286177366505 1.000000000444596 0.9732278757409815 0.0002811859178771803 0.08335792799264789 4.5638061799490256e-10 1.8866861965488754e-10 0.07863738959528957 0.01907236815251875 5.366938404448211e-11 10.270273389017373 -0.026772124703614453 LSAMLVPVT(ph)PEVKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSAMLVPVTPEVKPK 15 1 Q5JSK7;Q5JSK8;Q5JSL0;Q5JSK6;P82970 Q5JSK7 HMGN5 High mobility group nucleosome-binding domain-containing protein 5 1 LSAMLVPVT(1)PEVKPK 62.658 0.027322000000000003 6551900.0 48462.0 38006.0 39487.0 42203.0 58804.0 50170.0 53118.0 43432.0 39288.0 40853.0 True False 56665.65943186989 41778.98450709632 40428.51983528142 39838.502733972105 47281.77832804603 47538.99688076266 48086.27849898286 42291.95602000784 39862.51267440631 48259.325507829926 1.1741908705847135 0.8657183677446509 0.8377348711332904 0.8255089003991245 0.9797438698221074 0.9850737941426388 0.9964142265349525 0.876347847280752 0.8260064195870027 1.0 15.558520131545116 -4.7557640225166535 24.999136340570125 0.9087021316341579 1.1741912950350926 0.5631918863774621 0.06971279646088738 149.07624558345844 656592.1202803934 0.01877967779549151 0.16161848511496502 1.7548337462095433e-05 4.7557640225166535 0.26548916340093465 LSAS(ph)PAQEK ddPTM_PC-9_AZD4547_30min_R2 3 LSASPAQEK 9 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 LS(0.375)AS(0.625)PAQEK;LS(0.026)AS(0.974)PAQEK;LS(0.02)AS(0.98)PAQEK 128.88 0.0013159 59145000.0 236104.0 193095.0 269758.0 299736.0 265870.0 252250.0 248256.0 278829.0 250093.0 264001.0 True False 311180.1607317194 255509.18257146914 266180.83266325423 230636.49607503717 228958.539750258 236476.7676235693 270350.3030644023 235742.38490300294 263312.4054050211 254758.40534565088 1.2214716146833964 1.002947016506873 1.044836311885787 0.9053145695511573 0.8987281084587252 0.9282393148234798 1.0612026821945155 0.9253566514641689 1.0335769100444963 1.0 17.9587702210259 -3.948855580930549 1.2781208687047607 0.9658804873032025 2.608832261499569 0.6291202880991504 0.05642282763593791 6.440722095618877 1.867970549403774 0.016696961733358964 23.12018301220576 0.00011249790091389536 3.948855580930549 1.6429517741963666 LSAS(ph)PAQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LSASPAQEK 9 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 LS(0.072)AS(0.928)PAQEK;LS(0.067)AS(0.933)PAQEK;LS(0.003)AS(0.997)PAQEK 120.86 0.0016518000000000001 36132200.0 241466.0 228355.0 244317.0 269570.0 242186.0 227846.0 242592.0 253633.0 201279.0 172442.0 True False 282341.4246291097 251024.57525438015 250142.44385738228 254466.86685773113 194731.39184674824 215897.35466004064 219611.92954601566 246975.4024963771 204222.32459254313 203704.3695498789 1.3860351903741357 1.2322984323265311 1.2279679832598416 1.2491968995069718 0.955950980713089 1.0598562767067998 1.0780914029055308 1.2124207401250806 1.002542680080004 1.0 17.636117401526718 -6.1527526450151315 6.611732263188175 1.0642192338804564 1.2704398449268854 0.6680701698156373 0.07655896514398942 0.16742537511836328 8.892242785035885 0.023158876111226284 0.030043971350454786 7.034728729301852e-07 6.1527526450151315 0.20622061104642908 LSAS(ph)PAQEK ddPTM_PC-9_Lapatinib_30min_R1 2 LSASPAQEK 9 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 LS(0.004)AS(0.996)PAQEK;LS(0.004)AS(0.996)PAQEK 155.33 7.5817e-05 26640000.0 117738.0 128789.0 137383.0 116507.0 119102.0 109820.0 100227.0 104429.0 119965.0 83445.0 True False 116059.03452949543 128490.79698327281 126087.90005371608 125075.31343595845 112096.65452354145 105123.25460292354 105416.26364552247 109281.1525768077 106453.27841254593 97868.35706652641 1.1858688345059663 1.3128941859719856 1.2883418485099052 1.2779954337124306 1.145381999693152 1.0741291440242078 1.0771230539189018 1.116613743730503 1.0877190708349573 1.0 16.57855486060012 -6.422645766063564 2.8639834994972304 1.0793379467383606 1.2720362208910059 0.8273722641051159 0.0418565179391018 0.1070667955119814 1.7010751299237474 0.013762485380341142 0.015594429739499005 3.7788028474258496e-07 6.422645766063564 0.1926982741526453 LSAS(ph)SEDISER ddPTM_PC-9_AZD4547_30min_R2 1 LSASSEDISER 11 0 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 LS(0.001)AS(0.971)S(0.028)EDISER 111.94 0.0017500999999999997 23466000.0 26859.0 22020.0 43785.0 62650.0 58810.0 38944.0 29226.0 59982.0 35588.0 39805.0 True False 35399.60329809424 29137.53437543051 43204.38229138922 48207.01043285114 50645.24663449294 36508.82552361654 31827.057381735915 50713.16014923828 37469.10902565803 38411.439065699036 0.9215901345832593 0.7585639872953884 1.1247790591102906 1.2550170367321496 1.3184938618901825 0.950467527685483 0.8285827908529755 1.32026191631348 0.9754674632619402 1.0 15.229248394292064 -5.270004715540862 24.64633313067518 1.1068582992713103 0.8400770580944062 0.28945454913731894 0.1601465696686905 575.7841488149973 1656794.9662696817 0.04348322054880924 0.09294113168089914 5.370259653460574e-06 5.270004715540862 -0.26678124117690405 LSAS(ph)SEDISER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LSASSEDISER 11 0 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 LS(0.306)AS(0.657)S(0.037)EDISER;LS(0.001)AS(0.965)S(0.034)EDISER;LSAS(0.967)S(0.032)EDISER 136.93 6.2145e-05 36664100.0 77378.0 76002.0 85808.0 99315.0 103773.0 121247.0 105918.0 121688.0 100734.0 89628.0 True False 90476.56711483687 83546.97628028039 87853.98814865199 93750.7025335745 83439.42559071368 114888.59387685522 95884.68026008653 118493.8189390936 102207.04417999508 105876.84690514236 0.8545453492386019 0.7890958101078714 0.8297752598106979 0.8854693473972457 0.7880800007717371 1.0851153697444984 0.9056246295848983 1.1191664882621135 0.9653389496153475 1.0 16.692027610441983 -6.756295288054007 24.999999918832177 1.0156579699799415 0.8302909684523133 0.696563323772587 0.06126573311881156 68.65213319670126 333645.4504444685 0.01919790768780693 0.01864486731161552 1.7526883984302987e-07 6.756295288054007 -0.1853670015276282 LSAS(ph)SEDISER ddPTM_PC-9_Lapatinib_30min_R1 3 LSASSEDISER 11 0 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 LS(0.001)AS(0.974)S(0.025)EDISER;LS(0.002)AS(0.945)S(0.052)EDIS(0.001)ER;LS(0.018)AS(0.979)S(0.003)EDISER 123.26 0.00058861 47139000.0 102041.0 69666.0 71423.0 72353.0 81394.0 68363.0 58604.0 51262.0 72149.0 51515.0 True False 100585.87662797238 69504.69265726623 65550.87664075279 77674.08098253251 76606.56494676093 65439.27385193645 61638.22836842577 53643.8196611316 64022.81985734815 60419.29911057722 1.664797144433664 1.1503723757215596 1.0849327550255745 1.2855839462880265 1.2679154851922125 1.083085616934613 1.0201745017865518 0.887859019399656 1.059641882640444 1.0 15.882721827839742 -2.478222098481799 1.2398216850718449 1.082716710237367 199.99999997915108 0.696503117868146 0.1132040220359407 330.37469787659626 1.9715832446942312 0.0380102606574094 185311.45723354176 0.0033248947447401785 2.478222098481799 198.9172832689137 LSAS(ph)SSISSADLFEEPR ddPTM_PC-9_AZD4547_30min_R2 1 LSASSSISSADLFEEPR 17 0 H0Y6A0;Q9NP61-2;Q9NP61 H0Y6A0 ARFGAP3 ADP-ribosylation factor GTPase-activating protein 3 1 LS(0.045)AS(0.786)S(0.102)S(0.067)ISSADLFEEPR 154.81 2.6382e-05 2030000.0 5147.5 1148.9 3903.0 6168.4 6384.4 5705.4 3111.8 6266.4 5386.3 4371.1 True False 6784.297925348675 1520.2594570359736 3851.2436698251045 4746.37068082999 5498.036262765802 5348.640436073383 3388.7441716446256 5298.071867546706 5671.008821650612 4218.069119459295 1.6083894628588589 0.360415966163886 0.9130347466470126 1.1252472509123836 1.3034485939079594 1.2680305335439865 0.8033875395761703 1.2560419750129308 1.3444561151187504 1.0 12.042367020733504 -5.78650121136558 5.211487935122343 1.165852710216162 0.8989011116241243 0.06459035933373036 0.319709292334646 0.38206448178971064 27.467344026424545 0.08729860060912159 0.13804740667189516 1.6349285908623958e-06 5.78650121136558 -0.26695159859203765 LSASS(ph)EDISER ddPTM_PC-9_AZD4547_30min_R2 2 LSASSEDISER 11 0 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 LS(0.001)AS(0.316)S(0.674)EDIS(0.009)ER;LS(0.002)AS(0.282)S(0.716)EDISER 124.6 0.00050337 23734600.0 36768.0 32655.0 63426.0 95792.0 87785.0 58105.0 54706.0 76301.0 53849.0 66920.0 True False 48459.459178090365 43210.090146670445 62584.92979818782 73708.63437164693 75597.56802939929 54471.6851645886 59574.72802043535 64510.4336725523 56695.34820508764 64577.15116886273 0.7504118453812522 0.6691235114054571 0.9691497482528232 1.1414042434127558 1.1706550484353093 0.8435132888124879 0.922535710264664 0.9989668559993307 0.8779474965818023 1.0 15.97873617718748 -5.294918361831977 6.859508071948125 0.9952829304702431 0.7095929214557765 0.5623198892028443 0.09905030014141451 0.141823672964806 22.87319624686969 0.028223737597947284 0.06105089466136772 5.0708602075229575e-06 5.294918361831977 -0.2856900090144666 LSASTASELS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 LSASTASELSPK 12 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;H0YF21 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 LSASTAS(0.001)ELS(0.999)PK;LSASTASELS(1)PK;LSASTAS(0.04)ELS(0.96)PK;LSASTAS(0.016)ELS(0.984)PK 175.88 1.0204999999999999e-11 229402000.0 639723.0 563017.0 530439.0 583086.0 589078.0 517778.0 599686.0 502819.0 520050.0 551276.0 True False 843141.6069349857 745001.2348524862 523405.03227731446 448664.53128889797 507294.68792643794 485401.25980811164 653056.8922542827 425119.8771811521 547538.7812968829 531975.9950353557 1.584924159743241 1.4004414518797461 0.9838884407604302 0.8433924377717067 0.9536044721204433 0.9124495547507766 1.2276059415253875 0.7991335720945419 1.0292546776673501 1.0 19.021001621244473 -5.163167573341392 2.9927760527797926 0.9608735131795019 1.5595782714856203 0.7883987619163707 0.110412086523429 0.11217304931057619 1.8803052849089736 0.02892099997210472 0.10173087690567581 6.868033845057975e-06 5.163167573341392 0.5987047583061185 LSASTASELS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LSASTASELSPK 12 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;H0YF21 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 LSASTAS(0.005)ELS(0.995)PK;LSASTAS(0.001)ELS(0.999)PK;LSAST(0.001)AS(0.027)ELS(0.972)PK;LSASTAS(0.007)ELS(0.993)PK;LSASTAS(0.005)ELS(0.995)PK;LSASTAS(0.047)ELS(0.953)PK 158.86 7.509199999999999e-05 213481000.0 535771.0 445055.0 390315.0 566415.0 491421.0 424473.0 596064.0 559778.0 416732.0 388971.0 True False 626466.4483403992 489237.11913397355 399621.58987788094 534680.6038922074 395130.5827451656 402212.8886379904 539600.5027903488 545084.4206338183 422825.91712051234 459488.36320725776 1.3634000303459783 1.0647432194344761 0.8697099249445558 1.163643405809242 0.8599359948685734 0.8753494557087781 1.1743507474790076 1.1862855825751377 0.9202102838234265 1.0 18.809668799377093 -4.778421918781268 4.2396055058838265 1.011929920691429 1.3913707655524998 0.429154558357807 0.12271835077067975 0.20853327452841325 7.572834446438455 0.03160146798682257 0.23902628102161805 1.6656282619238926e-05 4.778421918781268 0.3794408448610709 LSASTASELS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 LSASTASELSPK 12 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;H0YF21 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 LSASTAS(0.018)ELS(0.982)PK;LSASTAS(0.002)ELS(0.998)PK;LSASTAS(0.001)ELS(0.999)PK;LSASTASELS(1)PK 175.21 0.00023464 454443000.0 1348180.0 1457060.0 910940.0 1188160.0 1120080.0 1008600.0 1045290.0 1078100.0 937680.0 972220.0 True False 1328954.7059740678 1453686.2670914975 836046.0295300895 1275541.249985569 1054199.0965620072 965464.5291614353 1099410.0015567492 1128192.4617975492 832068.6041918574 1140266.931598278 1.1654768450675947 1.2748648819043704 0.7332020304738899 1.1186339046048464 0.924519572872615 0.8467004544349739 0.9641689775355838 0.9894108392814616 0.729713877631768 1.0 20.120940161972385 -5.244980916606589 24.955892008339347 0.9200886654259649 1.2201709093174065 0.5266205695965579 0.11623778098744333 600.0024190135151 909777.5132604596 0.028038343594970358 0.07372256905056986 5.688779274377033e-06 5.244980916606589 0.30008224389144156 LSCFAQTVSPAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSCFAQTVSPAEK 13 0 Q16658 Q16658 FSCN1 Fascin 0 131.69 0.00030053 2221600.0 6250.9 10897.0 8922.2 11103.0 10516.0 10024.0 9503.4 9099.6 11756.0 7922.0 False True 7309.053909097346 11978.782144235878 9134.939085631933 10480.934906411674 8455.46528973764 9498.323793756517 8603.169153342249 8860.745141823161 11927.909259833048 9358.1958894825 0.7810323694240953 1.2800311390893842 0.9761431790392974 1.119973874258285 0.9035358299392491 1.0149738160996933 0.9193191994421904 0.9468433068153217 1.2745949540593182 1.0 13.192014712743417 -8.236813866583788 24.952568726242404 1.1372975980088498 1.0013178388425272 0.1422596871664622 0.14073382104858942 1282.2189224801284 1299252.090577759 0.08970140456165163 0.03386967758183876 5.796770858546717e-09 8.236813866583788 -0.13597975916632254 LSCFAQTVSPAEK ddPTM_PC-9_Lapatinib_30min_R1 2 LSCFAQTVSPAEK 13 0 Q16658 Q16658 FSCN1 Fascin 0 ; 189.24 0.00010963 7022900.0 30438.0 28758.0 31483.0 25127.0 27525.0 29968.0 29126.0 29222.0 26884.0 30211.0 False True 30003.94853835443 28691.412617886268 28894.589267894433 26974.92340121479 25906.033616232085 28686.338498820012 30634.001765387467 30579.760800155807 23856.040818929567 35432.93109637289 0.8467814434190514 0.8097386168773172 0.8154727360630981 0.7612952856721494 0.7311287216338692 0.8095954133965649 0.8645630157456359 0.8630322091328797 0.6732731411365401 1.0 15.112803193108796 -7.007969707943153 24.202266871677683 0.8385568463090884 0.7910240653194605 0.09732829044647595 0.07948966536429625 718.1537927288376 2180878.5560348406 0.028076897229955693 0.023665914391824066 9.818164223650292e-08 7.007969707943153 -0.04753278098962799 LSCS(ph)ELSLYQPLQNSSK ddPTM_PC-9_Lapatinib_30min_R1 1 LSCSELSLYQPLQNSSK 17 0 Q12923-3;Q12923;Q12923-4 Q12923-3 PTPN13 Tyrosine-protein phosphatase non-receptor type 13 1 LS(0.001)CS(0.778)ELS(0.221)LY(0.001)QPLQNSSK 121.51 0.00060642 0.0 9295.5 8131.6 10592.0 6598.0 8397.9 7659.0 6499.4 8569.7 11029.0 7160.4 True False 9162.944465414079 8112.771779804013 9721.16664630238 7083.238930282776 7903.952032906649 7331.442424001023 6835.907130191561 8967.879547227956 9786.797879481255 8398.065599366737 1.0910779818277458 0.9660286269275824 1.1575483105342035 0.8434369613422517 0.9411634071425511 0.8729918023686141 0.8139859172696898 1.0678506188263386 1.1653633522723659 1.0 13.035841342126687 -11.053957377303968 9.120261548230182 1.0000009000239902 0.9829807817630963 0.0 0.12032892588090781 2.2953951267975213e-06 1.1806506496544707e-07 0.12144192905891442 0.02945243652790235 8.831665722387193e-12 11.053957377303968 -0.01702011826089389 LSCS(ph)LEDLR ddPTM_PC-9_Lapatinib_30min_R1 1 LSCSLEDLR 9 0 H0YDJ2;E9PP16;Q8ND30-3;Q8ND30-2;Q8ND30;E9PI79 H0YDJ2 PPFIBP2 Liprin-beta-2 1 LS(0.055)CS(0.945)LEDLR 86.189 0.011855 1654500.0 14154.0 12657.0 15318.0 11682.0 14075.0 15840.0 13319.0 15762.0 15392.0 16686.0 True False 13952.16136447429 12627.693494143761 14058.613169189946 12541.133250009605 13247.136172514694 15162.560124843478 14008.592649632488 16494.360062009993 13658.390875054452 19570.152867302568 0.7129306275264354 0.6452526753248753 0.7183701253902214 0.6408296008235627 0.6769050943208396 0.7747798511158689 0.7158141658176709 0.8428324588904182 0.6979194780779984 1.0 14.256367404805836 -14.52287872670722 0.15659912390010355 2.078764394554291 0.6319067852896912 0.7594282967817123 0.050418870305035286 59.456677813566415 0.5392472856660685 19.79375035422813 0.21574715584716303 3.000000128298559e-15 14.52287872670722 -1.4468576092645997 LSDDFDS(ph)PVKGPLCK ddPTM_PC-9_Lapatinib_30min_R1 1 LSDDFDSPVKGPLCK 15 1 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 LS(0.15)DDFDS(0.85)PVKGPLCK 69.069 0.038993 0.0 10133.0 7345.5 8658.6 7223.1 8938.7 7449.1 5019.4 8953.8 5936.4 5806.8 True False 9988.501561835377 7328.491946056175 7946.72333116256 7754.3108695552455 8412.943240160359 7130.519357700227 5279.279971887177 9369.82623545394 5267.78011893667 6810.497642925363 1.466633142764725 1.0760582163432502 1.166834458773727 1.138582123673488 1.235290529598757 1.0469894758876097 0.7751680198246907 1.3757917154831067 0.7734794717106696 1.0 12.733544504448586 -1.5228787452803376 0.35945761777907376 1.0074724656698724 5.449139921438102 0.30677317988814945 0.17856441494387726 87.9040722865661 1.2275929387803017 0.14148260439802382 267.00249930520556 0.029999999999999995 1.5228787452803376 4.44166745576823 LSDEEMATILSFNR ddPTM_PC-9_AZD4547_30min_R2 1 LSDEEMATILSFNR 14 0 O60218;C9JRZ8;C9JRZ8-2 O60218 AKR1B10;AKR1B15 Aldo-keto reductase family 1 member B10;Aldo-keto reductase family 1 member B15 0 137.01 0.00029671 2590300.0 1981.7 4615.5 5934.5 9450.7 7268.2 6708.5 3903.7 6414.0 5499.5 5570.2 False True 2611.839378079355 6107.370113978181 5855.804652466585 7271.987126859473 6259.135888264274 6289.016434500347 4251.121737531048 5422.863679057291 5790.192342548229 5375.18899343693 0.4859065199881145 1.1362149538249238 1.0894137228693694 1.3528802681614585 1.164449453946017 1.1700084298764553 0.7908785612415934 1.0088693970907017 1.0772072106893387 1.0 12.392099765894558 -4.758902883149052 24.982873850210403 1.0920708344480137 0.48590571361379953 0.6345931236811754 0.1369772020373899 47.89127602028679 471600.72042367206 0.03715637998410809 0.24576953537766205 1.7421964194728858e-05 4.758902883149052 -0.6061651208342141 LSDEEMATILSFNR ddPTM_PC-9_Lapatinib_30min_R1 3 LSDEEMATILSFNR 14 0 O60218;C9JRZ8;C9JRZ8-2 O60218 AKR1B10;AKR1B15 Aldo-keto reductase family 1 member B10;Aldo-keto reductase family 1 member B15 0 ;; 141.89 0.0010767 19088600.0 38069.8 31959.699999999997 36797.5 33630.8 38243.8 35842.9 38373.3 30221.699999999997 33545.6 32699.0 False True 37526.91767085373 31885.69927824812 33772.15159245768 36104.121221060006 35994.374874203735 34309.98272088084 40360.08171200109 31625.9105117401 29767.341277171672 38350.97858132129 0.9785126497171335 0.8314181399735636 0.8806072971735405 0.9414132978250624 0.938551666885879 0.8946312190738048 1.052387271589944 0.8246441598531568 0.7761820526704827 1.0 15.226975770221783 -11.042503094096931 3.208764742754744 1.0027565922310206 0.9034910682092638 0.12804184909397565 0.07660727768400401 115172082.19207421 146016152.61489716 2805910.808071162 0.01942716313925317 9.067695043527672e-12 11.042503094096931 -0.09926552402175681 LSDGVAVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSDGVAVLK 9 0 P10809 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 121.09 0.007545100000000001 4306100.0 37860.0 33575.0 37657.0 42051.0 51718.0 37711.0 31038.0 35198.0 45171.0 33725.0 False True 44268.95023091484 36908.10411055515 38554.885694967794 39695.01880118141 41584.22916076939 35733.368773578644 28097.85594433958 34274.08979536372 45831.5404198638 39839.07553304688 1.1111942141878601 0.9264297330378446 0.9677655713417888 0.9963840342694203 1.043805073395212 0.896942720067324 0.7052838342353639 0.860313381693133 1.1504167656161126 1.0 15.28189654956179 -6.775764112327405 24.591283929900396 0.9002791714360547 1.0015175075039695 0.10718168575241382 0.11522394826375948 397.0534508728239 681617.0304714555 0.041723767172828385 0.03697387434976021 1.6758528707691264e-07 6.775764112327405 0.10123833606791477 LSDGVAVLK ddPTM_PC-9_Lapatinib_30min_R1 2 LSDGVAVLK 9 0 P10809 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 ; 122.19 0.007240399999999999 18369700.0 126634.0 127172.0 126037.0 113948.0 99140.0 96186.0 118937.0 104965.0 124343.0 98656.0 False True 124828.17593816856 126877.54104742459 115674.72437688932 122328.11603938518 93308.78011673923 92072.34900051726 125094.97589678947 109842.0570935717 110338.18195016225 115708.55814914338 1.0788154129210596 1.096526852265196 0.9997075949022677 1.0572088875371644 0.8064120892118299 0.7957263531176315 1.0811212057067325 0.9492993331745607 0.9535870441660941 1.0 16.82013604884517 -6.192953389124322 24.59473700907258 0.9292292020179332 1.0566439442608313 0.3651103899190572 0.08204093208705245 178.46317530104616 64089.192091783305 0.025847452270048286 0.03336891467620667 6.412783984214902e-07 6.192953389124322 0.12741474224289806 LSDIS(ph)PIGRDPSESSFSSATLTPSSTCPSLVDSR ddPTM_PC-9_AZD4547_30min_R2 1 LSDISPIGRDPSESSFSSATLTPSSTCPSLVDSR 34 1 A0A087WWA3;Q4R9M9;O60333-2;O60333;O60333-4;A0A0U1RQL3 A0A087WWA3 KIF1B;KIF1Bbeta Kinesin-like protein;Kinesin-like protein KIF1B 1 LS(0.059)DIS(0.747)PIGRDPS(0.117)ES(0.033)S(0.013)FS(0.013)S(0.013)AT(0.003)LT(0.001)PSSTCPSLVDSR 56.332 0.00040199 4219300.0 954.27 1910.4 1872.4 2926.6 3773.7 2821.4 2988.7 3113.3 539.62 3810.9 True False 1257.708009950943 2527.8994400918455 1847.5707525955736 2251.917585519267 3249.7868938035385 2644.977411984688 3254.688510120921 2632.2110215168454 568.1432115439361 3677.481550947681 0.34200253421443644 0.6873996252789928 0.5024010935199545 0.6123531972414522 0.8836990339125083 0.7192360791866057 0.885031907034909 0.7157645755798636 0.15449247091328752 1.0 11.844502388501661 -6.009306342711637 15.257112858445828 0.7223083070615497 0.5331217545934287 0.15349150725578053 0.2265783915490861 5.8281377681757744 9562.406050679141 0.06499628426704572 0.09017538585100347 9.787993162257405e-07 6.009306342711637 -0.189186552468121 LSDISPIGRDPSES(ph)SFSSATLTPSSTCPSLVDSR ddPTM_PC-9_AZD4547_30min_R2 1 LSDISPIGRDPSESSFSSATLTPSSTCPSLVDSR 34 1 A0A087WWA3;Q4R9M9;O60333-2;O60333;O60333-4;A0A0U1RQL3 A0A087WWA3 KIF1B;KIF1Bbeta Kinesin-like protein;Kinesin-like protein KIF1B 1 LS(0.004)DIS(0.027)PIGRDPS(0.068)ES(0.214)S(0.214)FS(0.214)S(0.214)AT(0.028)LT(0.012)PS(0.002)S(0.002)T(0.001)CPSLVDSR 52.143 0.001736 3560300.0 1341.3 875.91 3232.3 4066.1 2790.8 2865.9 2771.5 2856.8 2965.7 4617.5 True False 1767.8054992268444 1159.0307781463825 3189.4375900527 3128.7234656187725 2403.345592714555 2686.6948199499952 3018.1581308930777 2415.3472027332173 3122.4608474034508 4455.842730457616 0.39673875541951414 0.2601148308543084 0.7157877382546542 0.7021620050080744 0.5393694836414774 0.6029599746834132 0.6773484419148501 0.5420629382233966 0.7007565204355346 1.0 12.121482598131566 -14.522878745264398 0.06546332047783021 2.4783531960888974 1.3996374112240335e-12 0.6086225629168471 0.11902422543641847 268.7617311310841 1.270628991862077 61.76363601587152 8.734337565536636 3.0000000001101055e-15 14.522878745264398 -2.4783531960874976 LSDLDSETR ddPTM_PC-9_AZD4547_30min_R2 2 LSDLDSETR 9 0 Q9Y266 Q9Y266 NUDC Nuclear migration protein nudC 0 ; 106.6 0.011788 13530600.0 65779.0 61618.0 92230.0 126143.0 98352.0 87270.0 76668.0 109688.0 66168.0 79840.0 False True 86695.35371180388 81534.81349433599 91006.96993798853 97062.68023992251 84697.52247909614 81812.99310409866 83491.30347440382 92738.23997948796 69665.50539535064 77044.8259014047 1.1252586101336524 1.0582776006097694 1.1812210472699538 1.259820878356386 1.0993278456814828 1.061888220875414 1.0836717780535807 1.2036919922197802 0.9042204272679196 1.0 16.23341045248639 -8.266037218489636 24.99488061031885 0.9521101993863654 1.1321227103859253 0.5561738778172902 0.06502507371896353 321.1143687984137 1745615.7307024396 0.05878513334900773 0.017204901493125174 5.419544435987968e-09 8.266037218489636 0.18001251099955984 LSDLDSETR ddPTM_PC-9_Lapatinib_30min_R1 2 LSDLDSETR 9 0 Q9Y266 Q9Y266 NUDC Nuclear migration protein nudC 0 ; 119.21 0.008068200000000001 16821400.0 98541.0 96844.0 106283.0 87952.0 100077.0 118119.0 82672.0 86512.0 100526.0 90239.0 False True 97135.78726979392 96619.7636680775 97544.82200424444 94420.28347927086 94190.66761895227 113067.32571883741 86952.35164279724 90531.66334758338 89203.70329429088 105836.69091409062 0.9177893453664441 0.912913686488038 0.9216541178845357 0.8921318558222248 0.8899623259707579 1.0683187913595675 0.8215709589161087 0.8553901540730277 0.84284289809003 1.0 16.6914803346235 -10.610215948601537 6.850480902062725 1.0000000538152622 0.9038136556596024 0.17302040880341973 0.06388490115956051 5.370249150081431e-08 7.14900439590532e-09 0.06320376112078338 0.015329155028039023 2.4534886395585196e-11 10.610215948601537 -0.09618639815565988 LSDPPT(ph)SPSSPSQMMPHVQTHF ddPTM_PC-9_Lapatinib_30min_R1 1 LSDPPTSPSSPSQMMPHVQTHF 22 0 Q13496-2;Q13496 Q13496-2 MTM1 Myotubularin 1 LS(0.014)DPPT(0.344)S(0.292)PS(0.252)S(0.09)PS(0.008)QMMPHVQTHF 50.236999999999995 0.046060000000000004 8387100.0 22562.0 19933.0 23779.0 21347.0 29685.0 36691.0 32949.0 34213.0 48322.0 28582.0 True False 22240.26174263593 19886.846363179866 21823.982409594453 22916.92959150444 27938.9866629555 35121.8114608985 34654.93799930482 35802.66088069708 42879.46750678154 33522.360616878956 0.6634455728466109 0.5932412275633886 0.6510276128527114 0.6836311396270064 0.8334432942317268 1.0477129538190755 1.033785728737003 1.0680232603508826 1.2791303093729967 1.0 15.032836125554207 -6.584851121853489 1.305779570456969 1.113389730138973 0.6236859726662881 0.8965358459677213 0.07067948340235299 0.12268442911096962 0.4365407560173992 0.030751892464840027 0.03257250393129155 2.601051062622744e-07 6.584851121853489 -0.4897037574726849 LSDPPTS(ph)PSSPSQMMPHVQTHF ddPTM_PC-9_AZD4547_30min_R2 1 LSDPPTSPSSPSQMMPHVQTHF 22 0 Q13496-2;Q13496 Q13496-2 MTM1 Myotubularin 1 LS(0.004)DPPT(0.26)S(0.385)PS(0.26)S(0.09)PS(0.002)QMMPHVQTHF 56.562 0.0060156 13478000.0 21543.0 20375.0 46411.0 74281.0 54052.0 40606.0 28724.0 48667.0 27349.0 43646.0 True False 28393.225877763285 26960.820295158792 45795.55981559129 57156.66308000979 46547.81280543468 38066.900400882616 31280.380354238758 41146.63340640488 28794.612305909897 42117.96682480847 0.674135719700482 0.6401263481521676 1.0873164890907467 1.3570613063483201 1.1051771088346298 0.9038161922493447 0.7426849563833617 0.9769377894606381 0.6836657720369634 1.0 15.3621481738769 -6.994354294156567 24.37334296728541 0.845236022683732 0.9842474308495285 0.06634362644969438 0.21371591135596352 334.53646161098726 1444228.4578559913 0.08451116057045932 0.07429617886606882 1.0130845817859333e-07 6.994354294156567 0.1390114081657965 LSDPPTSPS(ph)SPSQMMPHVQTHF ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSDPPTSPSSPSQMMPHVQTHF 22 0 Q13496-2;Q13496 Q13496-2 MTM1 Myotubularin 1 LS(0.001)DPPT(0.036)S(0.108)PS(0.407)S(0.407)PS(0.042)QMMPHVQTHF 53.958 0.0080174 10479000.0 4805.2 2675.0 8209.0 10137.0 13807.0 15154.0 14199.0 13855.0 13541.0 7280.1 True False 5618.625452973903 2940.55632154088 8404.733692805867 9569.056754597423 11101.617464378805 14359.297562907659 12853.967928142205 13491.320930585951 13739.011507944815 8599.924500760113 0.6533342766529281 0.34192815544845495 0.9773031951690978 1.1126907862681412 1.2908970844334247 1.669700421397711 1.4946605551020935 1.5687720199629087 1.597573502736039 1.0 13.070108279028323 -5.740525238262184 1.2326297716899373 1.4948946421052658 0.4627817049560238 0.7585999723962098 0.20456567739477718 0.21667410001222825 0.6441821183027553 0.06829830833169737 0.18324486719454516 1.8175014321181175e-06 5.740525238262184 -1.032112937149242 LSDPPTSPSS(ph)PSQMMPHVQTHF ddPTM_PC-9_AZD4547_30min_R2 1 LSDPPTSPSSPSQMMPHVQTHF 22 0 Q13496-2;Q13496 Q13496-2 MTM1 Myotubularin 1 LSDPPT(0.001)S(0.008)PS(0.159)S(0.701)PS(0.132)QMMPHVQTHF 80.142 0.00026545 26471000.0 23364.0 16877.0 43180.0 58888.0 56553.0 41207.0 30152.0 45808.0 31308.0 45081.0 True False 30793.265998610303 22332.16020227706 42607.40498668922 45312.2814105305 48701.59212583712 38630.31977587475 32835.4695878362 38729.42616312071 32962.87696345121 43502.727911588496 0.7078467828774347 0.5133508006133127 0.979419154432824 1.0415963224793534 1.1195066255342512 0.8879976413061718 0.754791047921602 0.89027580619384 0.7577197694462369 1.0 15.40881824996198 -5.266514532095218 24.95366510176846 0.9281459540728763 0.6105987838331847 0.5395645913346008 0.11761770746448133 302.7908379672043 1488778.2945670455 0.033541934201890146 0.0734162368308475 5.413591329527993e-06 5.266514532095218 -0.3175471702396916 LSDPPTSPSS(ph)PSQMMPHVQTHF ddPTM_PC-9_Lapatinib_30min_R1 1 LSDPPTSPSSPSQMMPHVQTHF 22 0 Q13496-2;Q13496 Q13496-2 MTM1 Myotubularin 1 LSDPPT(0.003)S(0.004)PS(0.177)S(0.595)PS(0.221)QMMPHVQTHF 74.324 0.00048896 12022000.0 33077.0 27623.0 43467.0 27912.0 34279.0 36016.0 31543.0 36934.0 46980.0 34116.0 True False 32605.315914421095 27559.04064065206 39893.311047472234 29964.741591702445 32262.776615106995 34475.679637396635 33176.14219891564 38650.08847419595 41688.617678668015 40012.90514328745 0.8148699975085651 0.6887538043529278 0.997011111905348 0.7488769306901806 0.8063092769588461 0.8616140096285977 0.8291360519839999 0.9659405718177372 1.0418793019247112 1.0 15.288177759136676 -7.8407086928281045 2.766322192206297 1.0203206227965709 0.8187692238304267 0.5568270017788093 0.07526969179108049 0.2018440222123665 3.0527677932531656 0.04872790149508154 0.020449244110344433 1.4430829886608987e-08 7.8407086928281045 -0.20155139896614416 LSDQFHDILIR ddPTM_PC-9_AZD4547_30min_R2 2 LSDQFHDILIR 11 0 H0Y9X3;A0A024QZ42;A0A087WZ38;O75340-2;O75340 H0Y9X3 PDCD6 Programmed cell death protein 6 0 ; 163.45 0.00094054 7895400.0 39701.0 37070.0 64413.0 109253.0 88018.0 70819.0 49403.0 90919.0 56988.0 73426.0 False True 52325.09216790049 49052.152556639856 63558.84153329348 84066.40879202374 75798.22000127194 66390.67673472172 53799.771293707636 76869.55766077462 60000.26933669219 70855.37808913515 0.7384773545640558 0.6922855241126916 0.8970221209367802 1.1864506415627234 1.069759586998728 0.9369885324894197 0.7592898767123678 1.0848796482896994 0.8467990850491635 1.0 16.112589740781047 -5.392910802567364 4.353552648611826 0.9830170660980122 0.7177998704293648 0.4554256890797883 0.11522511947501726 0.20368711443882312 6.1791385721214525 0.03218088337103038 0.070672469870711 4.0465899392064655e-06 5.392910802567364 -0.26521719566864743 LSDQFHDILIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSDQFHDILIR 11 0 H0Y9X3;A0A024QZ42;A0A087WZ38;O75340-2;O75340 H0Y9X3 PDCD6 Programmed cell death protein 6 0 80.245 0.01375 3327600.0 10628.0 12082.0 15664.0 18297.0 22053.0 18021.0 18476.0 18512.0 15521.0 13672.0 False True 12427.110487431668 13281.421112843707 16037.489166050806 17271.878409674373 17731.87295878511 17075.94703584261 16725.81952534372 18026.07961508531 15747.965262152833 16150.625372507558 0.7694507302847695 0.8223471727263292 0.9929949333943849 1.069424744324481 1.0979062760609402 1.0572932404778692 1.0356143579316306 1.1161227010918258 0.9750684508452437 1.0 13.979302408514938 -5.280673166044349 2.3659042763367752 1.056626906711739 0.7720440680407007 0.8639793704489158 0.03996410631385941 0.09611359737883023 1.015723836323362 0.010538459523284865 0.03522231123948632 5.239946272060864e-06 5.280673166044349 -0.2845828386710384 LSDQFHDILIR ddPTM_PC-9_Lapatinib_30min_R1 1 LSDQFHDILIR 11 0 H0Y9X3;A0A024QZ42;A0A087WZ38;O75340-2;O75340 H0Y9X3 PDCD6 Programmed cell death protein 6 0 130.44 0.00017562 2855400.0 20883.0 19870.0 31758.0 22865.0 27372.0 28489.0 26824.0 25509.0 29634.0 23685.0 False True 20585.204590526828 19823.99223580917 29146.97982942515 24546.568375404004 25762.03277542254 27270.591881102646 28212.815469159974 26694.241265182893 26296.30686014577 27778.920691721283 0.7410368753693753 0.7136343580734276 1.0492481026489837 0.8836401042290822 0.9273950223379334 0.9817009157317573 1.0156195693221444 0.9609531472235475 0.9466280980449553 1.0 14.761702926206748 -5.251127747100675 24.979353248913096 0.9666022728051824 0.727335577942741 0.8268895148135764 0.04450019645429644 263.68490617042914 638758.9377863739 0.011421284652375593 0.029497110028572533 5.608829688422988e-06 5.251127747100675 -0.23926669486244145 LSDS(ph)ENEEPSR ddPTM_PC-9_Lapatinib_30min_R1 1 LSDSENEEPSR 11 0 Q8NCN4 Q8NCN4 RNF169 E3 ubiquitin-protein ligase RNF169 1 LS(0.109)DS(0.89)ENEEPS(0.001)R 92.65 0.020243 0.0 7225.9 8352.2 8497.1 6620.7 9029.4 8670.4 8863.6 8880.5 10051.0 8128.5 True False 7122.85734093223 8332.860994057637 7798.501237754526 7107.608364007751 8498.30844448342 8299.58720368957 9322.513838072113 9293.120449859141 8918.950538277828 9533.500394454573 0.7471397751318538 0.8740610110956389 0.8180102706337268 0.7455402601275488 0.8914153346473557 0.870570814526557 0.9778689308593109 0.9747857623486065 0.9355378580008015 1.0 13.218790307245179 -6.89282287864676 1.4405092052802833 0.9723218066419289 0.8053824594898935 0.7503359135154715 0.04348902248010608 0.20670861665162304 0.8857592281242074 0.020901515592573493 0.01689644621012896 1.27990318958949e-07 6.89282287864676 -0.1669393471520354 LSDS(ph)YSNTLPVR ddPTM_PC-9_AZD4547_30min_R2 1 LSDSYSNTLPVR 12 0 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L0Y9;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 LS(0.014)DS(0.893)Y(0.003)S(0.072)NT(0.018)LPVR 68.46300000000001 0.034454000000000005 4359500.0 8634.5 8908.8 10777.0 10381.0 12277.0 12286.0 8961.6 10067.0 9239.1 11250.0 True False 11380.091391242959 11788.395378920766 10634.089938433295 7987.820834851197 10572.550466445678 11517.754477792543 9759.16503908043 8511.376466646352 9727.459964003521 10856.140924233492 1.0482630495188106 1.0858734665654772 0.9795460479603276 0.73578824101486 0.9738774155782399 1.0609437145461305 0.8989534225090657 0.7840149207760313 0.8960329487147236 1.0 13.406223733253526 -5.522310734382926 24.99999627302984 0.9031521435277734 1.0584786618978668 0.33105575587669256 0.09077843976177022 22.90417511680354 1008083.0474425912 0.026008531007534683 0.04572689392580515 3.003926247271928e-06 5.522310734382926 0.15532651837009337 LSDSYS(ph)NTLPVRK ddPTM_PC-9_AZD4547_30min_R2 1 LSDSYSNTLPVRK 13 1 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L0Y9;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 LSDS(0.022)YS(0.561)NT(0.418)LPVRK 92.039 0.0070747 15424000.0 33310.0 19654.0 46221.0 56820.0 40063.0 26818.0 42334.0 22739.0 29262.0 31997.0 True False 43901.88710895863 26006.77114508226 45608.07933973511 43721.026860248996 34500.943987717954 25141.066220530705 46101.64398817518 19225.210040237558 30808.729580443007 30876.79476912882 1.4218408172616588 0.8422756098727029 1.4770988919269201 1.4159833359375136 1.1173745282075918 0.8142382137950147 1.4930838622624276 0.6226426733729263 0.9977955876186388 1.0 14.914235377923404 -6.519481671840202 23.936845349365473 0.9905899848642383 1.270270549458054 0.22790428727879808 0.2625431642420104 133.5445140957609 941012.2595556031 0.08455662093951133 0.08637033564627256 3.023558168466763e-07 6.519481671840202 0.27968056459381563 LSDSYS(ph)NTLPVRK ddPTM_PC-9_Lapatinib_30min_R1 1 LSDSYSNTLPVRK 13 1 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L0Y9;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 LSDS(0.031)YS(0.572)NT(0.396)LPVRK 106.29 0.0016665 14263000.0 92130.0 48519.0 58624.0 54804.0 41685.0 46331.0 25842.0 24141.0 41958.0 25311.0 True False 90816.20930542727 48406.65723649846 53804.16101518417 58834.468980784644 39233.170255863224 44349.531132836084 27179.972314122886 25262.678991053355 37232.24820267249 29685.972625212493 3.059229705962083 1.6306239262440863 1.812443934192944 1.9818946046866641 1.3216063610643578 1.4939558050784476 0.9155830148222517 0.8509971800485188 1.2542034136031943 1.0 14.85749376159938 -1.5228787452848804 0.31930747216343863 0.951296834996101 18.34306575613966 0.7771119853381002 0.2938048117366398 27.114177706163556 0.3870106848439493 0.28312669238232885 275.1671995387133 0.02999999999968619 1.5228787452848804 17.39176892114356 up LSDSYSNT(ph)LPVR ddPTM_PC-9_AZD4547_30min_R2 3 LSDSYSNTLPVR 12 0 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L0Y9;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 LSDSYS(0.004)NT(0.996)LPVR;LSDSYS(0.001)NT(0.999)LPVR;LS(0.001)DS(0.002)YS(0.037)NT(0.96)LPVR 139.77 0.00017952 71692000.0 131049.0 91202.0 163592.0 153399.0 133996.0 107474.0 167472.0 110851.0 90292.0 119175.0 True False 172719.85601146525 120681.2629476846 161422.66319088597 118035.23054092469 115392.96833932192 100753.63379019014 182376.6835637476 93721.52505256922 95064.65078522853 115002.71952404708 1.501876274981041 1.0493774707862464 1.4036421387159674 1.0263690374404018 1.0033933877119596 0.8760978367048315 1.5858467027435175 0.8149505110874534 0.826629589097243 1.0 16.811308452106168 -1.5228787452811454 0.3482160002698778 0.986057792951071 5.893761622481276 0.25361983939419297 0.23220458533247543 97.65150451131646 1.3764258231939144 0.20036837749442596 314.10547348836855 0.029999999999944196 1.5228787452811454 4.907703829530205 LSDSYSNT(ph)LPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSDSYSNTLPVR 12 0 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L0Y9;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 LSDSYS(0.007)NT(0.992)LPVR 106.55 0.0040536 19783000.0 33031.0 28518.0 28230.0 30506.0 27136.0 30177.0 23066.0 24632.0 22297.0 14590.0 True False 38622.495908012366 31349.078571103862 28903.1102628712 28796.847721786424 21818.895597405906 28594.46499642764 20881.02149662145 23985.43609976132 22623.051443220273 17235.05150562354 2.2409272113524246 1.8189141216592897 1.676995873986251 1.6708303837902916 1.2659605682226551 1.6590878760703263 1.2115438987697997 1.3916660528653033 1.3126187314171185 1.0 14.07305798964405 -1.5228787452803376 0.24907633090390613 1.1347022956467279 7.65483245509125 0.8299437307125388 0.14076263493835786 19.479918411695163 0.2644750618663103 0.1748666833071807 53.14566030212482 0.029999999999999995 1.5228787452803376 6.520130159444522 up LSDSYSNT(ph)LPVR ddPTM_PC-9_Lapatinib_30min_R1 3 LSDSYSNTLPVR 12 0 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L0Y9;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 LSDSYSNT(1)LPVR;LSDSYSNT(1)LPVR;LSDS(0.005)YS(0.005)NT(0.989)LPVR 132.65 0.00019803 73764600.0 124507.0 118504.0 130255.0 133908.0 91393.0 107657.0 106897.0 89197.0 93133.0 72603.0 True False 122731.50734821262 118229.61126886406 119545.93669884026 143756.0410239929 86017.44342555128 103052.76107072449 112431.60360896187 93341.41824965784 82643.38080603213 85152.33181258349 1.441317046001033 1.3884483108352474 1.4039067886238932 1.6882220129965857 1.0101595763093354 1.2102165481215366 1.3203584824478893 1.0961698436526455 0.9705357333951412 1.0 16.377758416774334 -7.053713005328121 0.5543811789866956 0.9857119213668174 1.4777743162712402 0.5489640203686519 0.15013207050824742 0.7293103850026671 0.4752357373861544 0.14047444518034932 0.1319725351598826 8.836636586640726e-08 7.053713005328121 0.49206239490442283 LSDSYSNT(ph)LPVRK ddPTM_PC-9_AZD4547_30min_R2 1 LSDSYSNTLPVRK 13 1 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L0Y9;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 LSDS(0.001)YS(0.097)NT(0.902)LPVRK 63.54600000000001 0.038223 9661000.0 47184.0 29645.0 62672.0 71750.0 56655.0 39565.0 47486.0 41582.0 29488.0 42020.0 True False 62187.53051183137 39227.16651042861 61840.928330842675 55209.14602644968 48789.43118648524 37090.99429544701 51712.16200742871 35156.45735930155 31046.675479054873 40548.892589892566 1.5336431290686485 0.9674041386818683 1.525095369589883 1.3615451002529082 1.2032247509182719 0.9147227439866634 1.2753039282833278 0.8670139950521075 0.7656602559546529 1.0 15.307374893822173 -7.003098799358923 0.875300461665579 0.888914704519573 1.3384307056357723 0.46103704789247246 0.1927609186399077 0.5636913664176669 0.8968397098840921 0.13498946886130214 0.0989585405467201 9.928901462437485e-08 7.003098799358923 0.44951600111619927 LSDSYSNT(ph)LPVRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSDSYSNTLPVRK 13 1 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L0Y9;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 LSDS(0.01)YS(0.308)NT(0.683)LPVRK;LSDSYS(0.022)NT(0.978)LPVRK 103.3 0.0052287 40042800.0 129708.0 64967.0 92753.0 123545.0 90171.0 129415.0 91875.0 140589.0 114601.0 69497.0 True False 151665.0025502248 71416.49440805463 94964.58328771117 116623.17418829426 72502.63984793972 122628.24957791295 83171.93488260199 136898.68771635884 116276.82282120876 82096.25596205087 1.847404620014976 0.8699117099940223 1.156746823285202 1.420566295279087 0.8831418558411992 1.4937130584200826 1.0131026550230056 1.6675387459769235 1.4163474504240232 1.0 16.32502880827422 -7.75194321132803 24.999845452243903 1.406457371797637 1.2260708467163974 0.02193442823159697 0.3199369439938697 575.5402076916552 1515191.2512098537 0.14316321031206036 0.08125283513939836 1.770340434225209e-08 7.75194321132803 -0.18038652508123953 LSDSYSNT(ph)LPVRK ddPTM_PC-9_Lapatinib_30min_R1 1 LSDSYSNTLPVRK 13 1 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L0Y9;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 LSDSYS(0.079)NT(0.921)LPVRK 129.17 0.0003273 16168000.0 169950.0 122330.0 117310.0 109050.0 65015.0 78940.0 65228.0 48144.0 75172.0 53283.0 True False 167526.48183498738 122046.75240093275 107665.22462969503 117069.9007801356 61190.945524408016 75563.92021812777 68605.1866769448 50380.945998312985 66705.33776374694 62492.89555486537 2.680728430768714 1.9529700347103027 1.7228394311665525 1.8733313561595908 0.979166431337554 1.2091601700834416 1.0978077758729097 0.8061867761285161 1.0674067375416023 1.0 15.931404567238623 -4.057177650735731 0.4048104652483589 0.8940533705443384 5.152828334091914 0.8895834292734499 0.18759533785413166 3.0041251995172744 0.2471595683965162 0.1444677877039246 6.957211103648151 8.766421521148456e-05 4.057177650735731 4.258774963547575 up LSDT(ph)PAPK ddPTM_PC-9_AZD4547_30min_R2 2 LSDTPAPK 8 0 I3NI13;I3L270;J3KNE2;H3BNM4;Q8NBZ0-2;Q8NBZ0 I3NI13 INO80E INO80 complex subunit E 1 LS(0.377)DT(0.623)PAPK;LS(0.001)DT(0.999)PAPK 85.355 0.032491 17252400.0 127917.0 116139.0 153658.0 197742.0 195257.0 198101.0 170526.0 196036.0 164856.0 187687.0 True False 168591.94516111253 153678.66052807105 151620.3945216464 152155.63698344518 168148.9359311548 185713.71315360372 185702.4836473652 165743.14065913204 173569.95159980547 181116.1352574768 0.9308499484126043 0.8485089432236376 0.8371445995471419 0.8400998440428235 0.9284039530332971 1.0253846952376218 1.0253226935489121 0.9151207893405503 0.9583351110769696 1.0 17.46655555313245 -6.4873539643551945 4.430425423383939 0.9820866027947993 0.8622337430461796 0.6787446084843225 0.039042494547593995 0.13301152163573127 5.992055893638873 0.013594394609341007 0.014856498742983178 3.255712415163531e-07 6.4873539643551945 -0.1198528597486197 LSDT(ph)PAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSDTPAPK 8 0 I3NI13;I3L270;J3KNE2;H3BNM4;Q8NBZ0-2;Q8NBZ0 I3NI13 INO80E INO80 complex subunit E 1 LS(0.025)DT(0.975)PAPK 83.869 0.03532 3906300.0 49567.0 59014.0 54082.0 55567.0 62016.0 50984.0 53288.0 60557.0 43233.0 38004.0 True False 57957.714107125066 64872.51991006112 55371.51998712713 52453.76114064464 49864.40998558094 48310.30928779755 48240.17486828948 58967.4429154452 43865.200836199554 44893.82436050153 1.2909952523028403 1.4450210209121155 1.233388350755969 1.168395918321329 1.1107186945172047 1.076101445487498 1.0745392168178067 1.3134867379961044 0.9770876386907466 1.0 15.454229379588144 -5.62651037735159 2.110717454868414 1.1087009296607708 1.3686821162108445 0.5609106040214416 0.09427973181300678 0.2313311812373211 2.0711750290189044 0.026772109006808188 0.059514439896873994 2.3631409318528718e-06 5.62651037735159 0.25998118655007363 LSDT(ph)PAPK ddPTM_PC-9_Lapatinib_30min_R1 1 LSDTPAPK 8 0 I3NI13;I3L270;J3KNE2;H3BNM4;Q8NBZ0-2;Q8NBZ0 I3NI13 INO80E INO80 complex subunit E 1 LS(0.019)DT(0.981)PAPK 87.258 0.028999999999999998 8487100.0 82142.0 68465.0 81091.0 77537.0 87378.0 69621.0 71674.0 61918.0 79492.0 57979.0 True False 80970.64001700196 68306.47349897689 74424.01100031217 83239.32963584969 82238.59783175758 66643.47212447775 75384.92901642462 64794.93632277213 70538.77387213019 68000.59289783862 1.1907343240175718 1.0044982049141515 1.0944612073033515 1.2240971157546396 1.2093805998913798 0.9800425155792427 1.1085922313895105 0.9528584025747755 1.0373258653509805 1.0 16.053259704839522 -6.771048024012104 24.999965016135196 1.0186192220008707 1.1384761641530727 0.45437125130254774 0.0704138791083177 216.20388560188977 562520.4728205879 0.026000677624928185 0.023218641798683836 1.6941504519920017e-07 6.771048024012104 0.119856942152202 LSDVDANTAIKHEEQS(ph)NEDIPIAEQSSK ddPTM_PC-9_AZD4547_30min_R2 2 LSDVDANTAIKHEEQSNEDIPIAEQSSK 28 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 LSDVDANT(0.011)AIKHEEQS(0.979)NEDIPIAEQS(0.005)S(0.005)K;LS(0.001)DVDANT(0.001)AIKHEEQS(0.999)NEDIPIAEQSSK 72.286 3.6661999999999996e-05 24317700.0 64237.2 56269.4 65091.0 94376.1 87076.0 83124.0 63251.5 80159.0 71450.9 72291.2 True False 84663.29338323617 74457.38314190964 64227.85081029614 72619.14824120999 74987.00044116816 77926.24313951068 68880.7609656083 67772.26842057281 75227.64870409657 69760.30709172865 1.2136313171888908 1.0673316423909194 0.9206933496700664 1.0409809140565023 1.0749236000719846 1.1170570541933615 0.9873918828229378 0.9715018646844295 1.0783732446185887 1.0 16.09011877056364 -4.803253048159857 3.986742475842791 1.0255702108103493 1.2263133838018052 0.5167963908314201 0.05486792732066908 0.18332425167079747 5.312697172464888 0.014417238927632256 0.10090482659610361 1.573066026995772e-05 4.803253048159857 0.20074317299145594 LSDVDANTAIKHEEQS(ph)NEDIPIAEQSSK ddPTM_PC-9_Lapatinib_30min_R1 3 LSDVDANTAIKHEEQSNEDIPIAEQSSK 28 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 LSDVDANT(0.013)AIKHEEQS(0.986)NEDIPIAEQS(0.001)SK;LSDVDANTAIKHEEQS(0.999)NEDIPIAEQSSK;LS(0.002)DVDANT(0.005)AIKHEEQS(0.993)NEDIPIAEQSSK 70.027 6.6352e-05 40015800.0 245996.0 180309.0 233234.0 215551.0 214165.0 225051.0 196708.0 210215.0 225720.0 168294.0 True False 242488.05192985872 179891.5055886521 214058.4008292763 231403.33959705665 201568.23576459006 215426.0933495042 206892.57774036398 219982.35632758678 200297.03666302565 197383.39366234108 1.2285129332849403 0.9113811564937833 1.0844802942007408 1.1723546510346896 1.0212015916060693 1.0914094106519838 1.048176211289031 1.1144927252791346 1.014761338056984 1.0 17.590641091947553 -8.400772794447663 5.7970710002900825 1.000838382629543 1.0780224681019754 0.1238118633702805 0.0806317034673094 0.4855552879891977 19.52904044735094 0.07314855580875797 0.01898632827584381 3.973993986117225e-09 8.400772794447663 0.07718408547243238 LSEAVWQPEEHYS(ph)SSPEK ddPTM_PC-9_Lapatinib_30min_R1 1 LSEAVWQPEEHYSSSPEK 18 0 F5H269;Q9Y485 F5H269 DMXL1 DmX-like protein 1 1 LSEAVWQPEEHY(0.175)S(0.275)S(0.275)S(0.275)PEK 51.495 0.03492 6769100.0 23932.0 17616.0 34586.0 20428.0 27254.0 28177.0 14629.0 25219.0 28443.0 15113.0 True False 23590.725291408715 17575.21123432382 31742.472585820826 21930.343265810312 25650.97330342561 26971.93539379511 15386.418039753267 26390.76680648584 25239.449821931757 17725.26191319333 1.3309098284099024 0.9915346425003838 1.790804149539486 1.2372366272053243 1.4471421313291277 1.5216663948823943 0.868050250264612 1.4888788067409355 1.423925352727535 1.0 14.113519324818103 LSEEAECPNPS(ph)TPSK ddPTM_PC-9_AZD4547_30min_R2 3 LSEEAECPNPSTPSK 15 0 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 LSEEAECPNPS(0.956)T(0.044)PSK;LSEEAECPNPS(0.826)T(0.174)PSK;LSEEAECPNPS(0.5)T(0.5)PSK 233.47 8.591900000000001e-32 241032700.0 150714.0 132990.0 168716.0 218058.0 185074.0 164431.0 134118.0 156387.0 128866.0 148017.0 True False 198637.91695405517 175976.41673880586 166478.71560292374 167788.0970625165 159379.66970978002 154149.10357625762 146054.24217900724 132220.98256575165 135677.5936748467 142834.9698828685 1.3906812674581566 1.2320261409591429 1.165531912384231 1.1746990054334085 1.115830876993771 1.0792112302937247 1.0225384042771788 0.9256905551503192 0.9498905890210836 1.0 17.12398970800703 -4.7255655827634095 0.3381168734935855 0.9377938215533828 1.6942513550213487 0.9077827286274125 0.040864708198668255 2.1078532568564716 0.18859950644148676 0.04426570179160169 0.6637273495263893 1.8811976053180618e-05 4.7255655827634095 0.756457533467966 LSEEAECPNPS(ph)TPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LSEEAECPNPSTPSK 15 0 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 LSEEAECPNPS(0.686)T(0.314)PSK;LSEEAECPNPS(0.957)T(0.043)PSK;LSEEAECPNPS(0.963)T(0.037)PSK;LSEEAECPNPS(0.954)T(0.046)PSK;LSEEAECPNPS(0.946)T(0.054)PSK 196.18 1.0855999999999998e-09 81451700.0 107407.0 92170.0 96969.0 123659.0 250331.0 311165.0 367024.0 372475.0 317486.0 286900.0 True False 125588.88371505203 101320.0284696908 99281.10871698051 116730.78713788731 201280.43756611968 294846.95962532394 332256.82969634875 362697.9259198853 322128.6321254984 338912.69890085 0.3705641131841845 0.2989561288151445 0.2929400669817495 0.34442730389408416 0.5939005478959787 0.8699790848249754 0.9803611100260116 1.0701809849444257 0.9504767250392648 1.0 18.37055416938219 -6.639331567821917 1.6480029906974079 1.0092323271987078 0.31183667875710613 0.9866915674735534 0.035833109423088 0.03741212013794979 0.20944259350972524 0.014939154794957993 0.014963315005598906 2.2943962923067984e-07 6.639331567821917 -0.6973956484416017 down LSEEAECPNPST(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 1 LSEEAECPNPSTPSK 15 0 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 LSEEAECPNPS(0.111)T(0.888)PS(0.001)K 134.37 2.8649e-05 9729800.0 40931.0 35316.0 51411.0 66469.0 65643.0 53522.0 43506.0 46360.0 39716.0 49815.0 True False 53946.20658231116 46731.206357979296 50729.25654864934 51145.59898581299 56529.60253065844 50175.26087908288 47377.94971771036 39196.127246818796 41815.30667817904 48070.99201250595 1.122219540804915 0.9721290200506346 1.0552987243419447 1.0639597155079963 1.1759608063830247 1.043774192677977 0.9855829416914199 0.8153800370215304 0.8698656908786185 1.0 15.552878955372993 -7.479160332507062 3.154400820161417 0.8826817123617151 1.0707947004032001 0.5861278789492927 0.06619843971662714 0.17102723099230094 3.413457084285423 0.03275668319821727 0.01935258849796033 3.317719516234983e-08 7.479160332507062 0.18811298804148502 LSEEAECPNPST(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSEEAECPNPSTPSK 15 0 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 LSEEAECPNPS(0.063)T(0.745)PS(0.192)K 227.74 4.4952e-24 54657000.0 30310.0 27311.0 27768.0 38029.0 84527.0 88603.0 111200.0 102320.0 84462.0 81231.0 True False 35440.88435021208 30022.255587888973 28430.094430726418 35898.358421681514 67964.54113214673 83956.50270333281 100666.3309817181 99634.2084170016 85697.09696359475 95957.53727575798 0.36933924479912233 0.3128702178090765 0.2962778666257913 0.3741067084549972 0.7082772553534135 0.8749339039627789 1.0490716398069724 1.0383156054815974 0.8930731175115794 1.0 16.550108511277884 -6.489266662036199 1.7058266273568965 0.9946104520873922 0.3165156188579548 0.9739228179122065 0.049032734701511656 0.05264313993417697 0.3089897097961253 0.01942331680158276 0.021787749368683173 3.2414053004993276e-07 6.489266662036199 -0.6780948332294374 down LSEEAECPNPST(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 4 LSEEAECPNPSTPSK 15 0 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 LSEEAECPNPS(0.017)T(0.981)PS(0.001)K;LSEEAECPNPS(0.071)T(0.91)PS(0.018)K;LSEEAECPNPS(0.223)T(0.767)PS(0.01)K;LSEEAECPNPS(0.218)T(0.781)PS(0.001)K 253.06 2.0845999999999997e-49 140849700.0 96659.0 103276.0 135923.0 131215.0 292241.0 394661.0 405768.0 389089.0 442439.0 384716.0 True False 95280.6249349103 103036.87076725841 124747.93561795329 140864.98882040865 275051.9589479122 377782.26902972505 426776.68160192756 407167.4953792285 392606.8607307831 451213.6479981531 0.21116521044438863 0.22835495163851993 0.27647199097679753 0.3121913298619576 0.6095825340572102 0.8372580721035091 0.9458416949384351 0.9023829336405513 0.8701129996236064 1.0 18.783451180474643 -6.477102640473896 1.5350282704753495 0.9264950154810196 0.22910422129625954 0.9877278137394545 0.03456375529074049 0.03816310513108734 0.1825214275002572 0.013783138083387825 0.015770940462614735 3.333476206011203e-07 6.477102640473896 -0.6973907941847601 down LSEGPAAMAGPGS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSEGPAAMAGPGSPPR 16 0 Q8N2Y8 Q8N2Y8 RUSC2 Iporin 1 LSEGPAAMAGPGS(1)PPR 62.236999999999995 0.033686 6765200.0 27702.0 33977.0 31150.0 31581.0 38305.0 31012.0 33718.0 33775.0 35464.0 23878.0 True False 32391.401460560057 37350.01201382972 31892.734137032836 29811.618956983453 30799.410224743257 29385.676126494127 30523.98694281985 32888.44203757057 35982.59390870356 28206.892381856018 1.1483505882908147 1.324144875947234 1.1306716707845392 1.056891292858609 1.091910792858375 1.0417906279316453 1.082146396334475 1.1659718338460403 1.27566672079939 1.0 14.783760109200461 -5.443202040079603 7.713176570122203 1.1043342860092402 1.2353442099615672 0.29662957446951443 0.08143237532620849 0.359999152564364 31.121158649993735 0.021613604347160302 0.04511562813004078 3.6041093563033703e-06 5.443202040079603 0.13100992395232702 LSEGPAAMAGPGS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 1 LSEGPAAMAGPGSPPR 16 0 Q8N2Y8 Q8N2Y8 RUSC2 Iporin 1 LSEGPAAMAGPGS(1)PPR 58.658 0.046354 5295800.0 33128.0 34710.0 33158.0 27472.0 32750.0 29254.0 27711.0 25311.0 30457.0 22137.0 True False 32655.588645068863 34629.63112757605 30431.877233581414 29492.38252390549 30823.70938897734 28002.87461440473 29145.739989035657 26487.04146234837 27026.611933571578 25963.35095430162 1.2577570862307537 1.3337889700188565 1.1721089965291807 1.1359235784246555 1.1872007370400874 1.078553945663366 1.12257235363553 1.020170374346844 1.040952378648712 1.0 14.664188976028413 -5.15388608168005 0.28796714017987524 0.9886379722001226 1.5032184652436396 0.8303906999632519 0.041651619316964365 2.496565646931349 0.20281907962994777 0.05097593536069156 0.44695419678095644 7.0163931892596715e-06 5.15388608168005 0.5145804930435169 LSEGS(ph)QPAEEEEDQETPSR ddPTM_PC-9_AZD4547_30min_R2 1 LSEGSQPAEEEEDQETPSR 19 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 LS(0.012)EGS(0.988)QPAEEEEDQETPSR 166.61 8.225699999999999e-08 6445300.0 15297.0 14407.0 17638.0 28633.0 24887.0 19742.0 16632.0 23704.0 19058.0 21233.0 True False 20161.127802634033 19063.78100575965 17404.108595535534 22032.10422544016 21431.869630889745 18507.52961912586 18112.215779546692 20041.09146373151 20065.36697232187 20489.639132822205 0.9839669538317084 0.9304107740590472 0.849410205944331 1.0752802468905902 1.0459857048706236 0.9032628392892865 0.8839694863406776 0.9781085617866169 0.9792933317297572 1.0 14.322606955120062 -5.741885331908247 24.999998975036682 0.9753761786037157 0.9221775328316577 0.15892210488639602 0.06191285818446744 565.1181294002469 722502.4066762221 0.018353825688888215 0.031732949840554754 1.8118184093913372e-06 5.741885331908247 -0.05319864577205802 LSEGS(ph)QPAEEEEDQETPSR ddPTM_PC-9_Lapatinib_30min_R1 2 LSEGSQPAEEEEDQETPSR 19 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 LS(0.019)EGS(0.981)QPAEEEEDQETPSR;LSEGS(1)QPAEEEEDQETPSR 260.11 6.6185e-66 16122200.0 33863.0 30786.0 35227.0 33010.0 34215.0 32638.0 30404.0 33422.0 33766.0 33804.0 True False 33380.10741028636 30714.71690848621 32330.77204015237 35437.66551813189 32202.540969278158 31242.148822894007 31978.170352085443 34974.90813300962 29962.9175082568 39646.97635900131 0.8419332437367031 0.7747051535624317 0.815466272822394 0.89383021790226 0.8122319512511074 0.7880083600826951 0.8065727399367046 0.8821582714483356 0.7557428147091001 1.0 15.27492322383408 -10.904003706266879 4.99048753692726 1.000146701668672 0.8201447071576655 0.6307116651508933 0.04154970073218084 6.659783339478436e-05 8.258780513173175e-06 0.03950626097065616 0.009573894033723466 1.2473728691238587e-11 10.904003706266879 -0.1800019945110065 LSEGSQPAEEEEDQET(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 1 LSEGSQPAEEEEDQETPSR 19 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 LSEGSQPAEEEEDQET(1)PSR 206.45 4.4554e-20 6521800.0 36170.0 33049.0 42651.0 62227.0 50808.0 48363.0 32621.0 46356.0 45256.0 45388.0 True False 47671.30761726306 43731.44294158053 42085.419872331644 47881.526547566275 43754.18620991873 45338.85396463298 35524.205804749436 39192.74535490795 47648.13976804487 43798.97993503202 1.0884113668394777 0.9984580235989133 0.9608767129909844 1.093210997575514 0.9989772883939367 1.0351577601095983 0.8110738162725083 0.8948323776727998 1.0878824081912957 1.0 15.418609649836911 LSEGSQPAEEEEDQET(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSEGSQPAEEEEDQETPSR 19 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 LSEGS(0.297)QPAEEEEDQET(0.627)PS(0.075)R 114.87 0.00018837 5828400.0 4033.2 10863.0 14752.0 9478.6 8103.4 9951.3 9153.7 10054.0 9715.7 7136.7 True False 4715.941100668929 11941.406848934053 15103.743627271553 8947.544772035822 6515.596940743627 9429.436309737552 8286.595268951005 9790.093153093547 9857.773732201422 8430.52721591388 0.5593886336986001 1.4164484074486898 1.7915538661403025 1.0613268355442818 0.7728575893147541 1.118487144189284 0.9829272899218945 1.161267012413326 1.1692950487833549 1.0 13.041407139791595 -5.963560959324069 24.999941696203855 1.0323340694420515 1.2976251389494466 0.09386477526737547 0.30276998300497554 356.7679711827634 244767.70553331054 0.08691921219082566 0.12892164424726943 1.0875244775979044e-06 5.963560959324069 0.2652910695073951 LSEGSQPAEEEEDQET(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 2 LSEGSQPAEEEEDQETPSR 19 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 LSEGSQPAEEEEDQET(0.908)PS(0.092)R;LSEGSQPAEEEEDQET(0.977)PS(0.023)R 159.72 2.0229000000000002e-05 13186400.0 34943.0 29643.6 37936.4 31156.2 33055.0 25867.3 23822.5 25059.3 29344.3 22801.1 True False 34444.7064122386 29574.96206549734 34817.41563073882 33447.53088203641 31110.7698886304 24761.01587862144 25055.912485612294 26223.646561472317 26039.235924822013 26742.23975444401 1.2880262359668135 1.1059268908312958 1.3019633340529333 1.2507378285873798 1.1633569280022789 0.9259140635184332 0.9369414348118884 0.9806077128268392 0.9737118567450891 1.0 14.70683268070659 -6.651516175261247 4.192173368887076 0.9607095206329272 1.229455183795664 0.8543712773177365 0.05389823212253468 0.07945747414113023 2.51141239155493 0.018264875290139385 0.018107749719802762 2.2309191155408149e-07 6.651516175261247 0.26874566316273674 LSEHATAPTR ddPTM_PC-9_AZD4547_30min_R2 1 LSEHATAPTR 10 0 P33316-2;A0A0C4DGL3;H0YNJ9;H0YKC5;H0YNW5;H0YMM5;P33316;H0YKI0 P33316-2;H0YNW5;P33316 DUT Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial 0 65.695 0.044904 0.0 2862.7 1262.3 10921.0 26514.0 14472.0 10366.0 6017.8 16372.0 6591.6 14392.0 False True 3772.9790521409736 1670.3137893781084 10776.180404345358 20401.60693721653 12462.81260490362 9717.812381311853 6553.372541976672 13842.083591132829 6940.018518981892 13888.14046058387 0.2716691311445992 0.12026907375531301 0.7759268013546802 1.4689948589675212 0.8973708640314019 0.6997201971633362 0.47186825051027476 0.9966837266960428 0.49970826106478816 1.0 13.761565823513248 -5.302677399467688 5.988844105434205 0.858549360389121 0.19508405490615516 0.48470577925510083 0.27066677071972517 0.15742137363379644 15.66390737556113 0.07491660707343048 0.16340848129393595 4.981069489929558e-06 5.302677399467688 -0.6634653054829658 LSEHATAPTR ddPTM_PC-9_Lapatinib_30min_R1 1 LSEHATAPTR 10 0 P33316-2;A0A0C4DGL3;H0YNJ9;H0YKC5;H0YNW5;H0YMM5;P33316;H0YKI0 P33316-2;H0YNW5;P33316 DUT Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial 0 70.41199999999999 0.030083 1349000.0 6527.3 5497.2 14401.0 9119.6 14415.0 17718.0 10040.0 8769.1 15488.0 6867.6 False True 6434.219505039779 5484.471571146963 13217.005369467579 9790.285806093778 13567.138040980413 16960.242442675302 10559.822073902706 9176.544399173445 13743.578344129639 8054.655509498206 0.7988199492147643 0.6809070313037681 1.640915040237516 1.2154816297914768 1.6843846425190725 2.1056446700514324 1.3110209445270948 1.1392845278550132 1.7062900241882406 1.0 12.975607172120755 -5.257408366102895 24.867917650601683 1.495174323208556 0.7398634025802125 0.47187732115267067 0.31068186784702645 264.19095298113064 1629815.7960173704 0.08111727118244988 0.19873813733621357 5.528300399284832e-06 5.257408366102895 -0.7553109206283434 LSELLR ddPTM_PC-9_AZD4547_30min_R2 2 LSELLR 6 0 P07900;P07900-2;P08238;A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 P07900;P08238;A0A669KB10 HSP90AA1;HSP90AB1;GBF1 Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta;Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 0 ; 134.12 0.026723 179923000.0 149642.0 155208.0 203473.0 288650.0 225412.0 190926.0 173414.0 211773.0 169112.0 195803.0 False True 197225.0432530411 205375.95074213538 200774.81507310335 222106.20209804433 194117.43469434304 178987.36703784924 188847.51005256837 179048.34890941702 178050.91507100957 188947.9965677946 1.043805951032017 1.0869443152229796 1.0625929817735078 1.1754885266452273 1.027359052334242 0.9472837515566275 0.9994681789854799 0.9476064957649574 0.942327615562332 1.0 17.527629696093534 -6.526087497179648 6.013308340897967 0.9676950680621609 1.091368323675723 0.7159954248923488 0.03706317684684075 0.08249245379670711 12.054372390600676 0.012016322071744382 0.012565744837079163 2.9779164090581226e-07 6.526087497179648 0.12367325561356213 LSELLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSELLR 6 0 P07900;P07900-2;P08238;A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 P07900;P08238;A0A669KB10 HSP90AA1;HSP90AB1;GBF1 Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta;Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 0 134.12 0.026723 39527000.0 137030.0 124860.0 131230.0 136210.0 155790.0 151410.0 137870.0 135420.0 139190.0 109180.0 False True 160226.472534133 137255.2756290075 134359.02089254625 128578.5952987782 125264.06784787249 143469.7930579283 124809.95550763879 131865.36848935043 141225.39042839082 128973.46973159531 1.2423211755687262 1.0642132518776717 1.0417570464077515 0.9969383282186726 0.9712390316284241 1.1123977152549362 0.9677180568017505 1.0224224312470882 1.0949956663358194 1.0 16.976714803472575 -4.662431687346328 2.1679400766621053 1.0246363600505752 1.352126312967171 0.6713080297385363 0.04521776587472772 0.5918575157813755 2.396821749115424 0.011702275684938495 0.4243182325334817 2.1755462111671544e-05 4.662431687346328 0.3274899529165958 LSELLR ddPTM_PC-9_Lapatinib_30min_R1 1 LSELLR 6 0 P07900;P07900-2;P08238;A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 P07900;P08238;A0A669KB10 HSP90AA1;HSP90AB1;GBF1 Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta;Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 0 134.12 0.026723 61447000.0 68887.0 75328.0 78677.0 67867.0 81811.0 74153.0 73040.0 60571.0 72321.0 63106.0 False True 67904.65874767124 75153.58264413856 72208.48076200255 72858.16557767532 76999.03782661453 70981.64904908571 76821.65381253531 63385.34978530685 64175.4474061079 74013.7880165405 0.9174595783760725 1.015399760749218 0.9756085007548256 0.9843863897547451 1.0403336984915148 0.9590327822867657 1.0379370637720544 0.8563992126864468 0.8670742185464966 1.0 16.175506434752414 -7.7640364458755675 24.999518215608056 0.8963025338522437 0.9909705565089523 0.3541067009183989 0.05014213771290718 62.7343277774899 603859.2246711261 0.02434010377008456 0.01253555400825301 1.7217240823034507e-08 7.7640364458755675 0.0946680226567086 LSEPSLPIEDSQDLY(ph)NASPEPK ddPTM_PC-9_Lapatinib_30min_R1 1 LSEPSLPIEDSQDLYNASPEPK 22 0 E7ESG2;Q9HAW4-2;Q9HAW4-3;Q9HAW4 E7ESG2 CLSPN Claspin 1 LSEPSLPIEDSQDLY(0.998)NAS(0.002)PEPK 109.37 3.7584e-05 1586700.0 14004.0 13397.0 14472.0 14372.0 14191.0 13670.0 9304.2 13952.0 12687.0 8449.5 True False 13804.300391980929 13365.98006960922 13282.168023535498 15428.96482358655 13356.313280579472 13085.365966326412 9785.92595019976 14600.260854280132 11258.056459967245 9909.984816748954 1.392968874044101 1.3487387031127693 1.3402813696633709 1.5569110456667823 1.3477632435930524 1.3204224030909428 0.9874814271824593 1.473287913580261 1.136031655763983 1.0 13.274667131698697 -7.021975242254529 12.18476071816216 1.1836649697978574 1.3937409552515314 0.40925323153282267 0.13856171771657733 1.4352172278151032 793.2905866036515 0.05071326463025433 0.04035913639318778 9.506589861531734e-08 7.021975242254529 0.210075985453674 LSES(ph)QLSFR ddPTM_PC-9_AZD4547_30min_R2 2 LSESQLSFR 9 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 LS(0.001)ES(0.959)QLS(0.039)FR;LS(0.098)ES(0.902)QLSFR 119.03 0.00041230000000000005 3135400.0 15296.3 13637.5 20893.1 17434.9 19984.7 19954.9 18833.9 19616.8 15919.3 18888.6 True False 20160.205217194936 18045.5551791523 20616.043842690982 13415.553171519818 17210.16936603216 18707.116948470004 20510.08061390118 16585.47430921905 16760.76169810492 18227.315863242395 1.106043553996365 0.9900281157437647 1.1310520977071423 0.7360136441468004 0.9441965835868663 1.0263231892631643 1.1252386674914796 0.9099241179369522 0.9195408596558664 1.0 14.153814506702826 LSES(ph)QLSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSESQLSFR 9 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 LS(0.098)ES(0.902)QLSFR;LS(0.12)ES(0.88)QLSFR 97.779 0.004674 5837400.0 16057.0 20184.1 15894.1 16296.7 18942.0 14656.8 12810.8 16920.4 13866.0 11916.9 True False 18775.132959793973 22187.844055930196 16273.075622709917 15383.648733614267 15230.451076284748 13888.171606178223 11597.268281839855 16476.25742864572 14068.764018105234 14077.339635871496 1.3337131478984627 1.5761390028121316 1.15597662936563 1.092795168088015 1.0819125964308571 0.986562231601542 0.8238252810415975 1.170409882465389 0.9993908211360895 1.0 13.781087095855789 -5.472569100808223 2.966152224727355 1.0223619557847587 1.4547396638428696 0.7305165724596037 0.10306694696517937 0.12793600975608413 2.212212023300706 0.028617275285361 0.06523697179553432 3.368456158061498e-06 5.472569100808223 0.4323777080581108 LSES(ph)QLSFR ddPTM_PC-9_Lapatinib_30min_R1 1 LSESQLSFR 9 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 LS(0.034)ES(0.963)QLS(0.002)FR 107.09 0.0025256 3671300.0 9701.1 8130.3 12064.0 8902.7 8579.5 7218.8 10575.0 11805.0 9758.4 9426.9 True False 9562.760535036148 8111.474789874141 11072.144488386695 9557.434256536597 8074.870677945992 6910.068751844701 11122.52175612761 12353.503396271277 8659.306231492423 11056.327104445316 0.8649129538860456 0.7336500370555096 1.0014306183049722 0.8644312135712706 0.730339343406311 0.6249877275308211 1.0059870381056002 1.1173243410376685 0.7831991718127492 1.0 13.432584583544935 -7.317213101410567 24.99734637708877 0.9864048313566215 0.8085954492851234 0.32602336118490605 0.12162570670960846 369.1967375087809 165469.59344332432 0.052261211471349635 0.035234523468963955 4.817113714987515e-08 7.317213101410567 -0.1778093820714981 LSESS(ph)ASPQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSESSASPQPK 11 0 Q8N5Y2;Q8N5Y2-3;Q8N5Y2-2;A0A3B3IT59;Q8N5Y2-6;Q8N5Y2-4;A0A3B3ITL5;A0A3B3ITF3;A0A3F2YNX2;A0A3B3IRN2;A0A3B3IU80;A0A3B3IUB0;A0A3B3IS72;A0A3B3ISB4;A0A3B3IRI6;A0A3B3ITV8;A0A3B3IRT2;A0A3B3ITF8;A0A3B3IT49;Q8N5Y2-5;A0A3B3ITX5 Q8N5Y2 MSL3 Male-specific lethal 3 homolog 1 LS(0.003)ES(0.03)S(0.484)AS(0.484)PQPK 74.392 0.022887 14642000.0 32311.0 25245.0 36647.0 40382.0 37838.0 33370.0 36181.0 43039.0 32225.0 26936.0 True False 37780.61412866057 27751.15676160729 37520.80346452144 38119.527460210425 30423.915522355706 31620.018455472386 32753.673752244056 41909.27185358992 32696.229661289544 31819.283574741312 1.187349615836463 0.8721490129223598 1.1791844205538962 1.198000808870202 0.9561470939750111 0.9937375988117122 1.029365531606264 1.3171029371276672 1.027560208402818 1.0 14.957613732666443 LSESSAS(ph)PQPK ddPTM_PC-9_AZD4547_30min_R2 2 LSESSASPQPK 11 0 Q8N5Y2;Q8N5Y2-3;Q8N5Y2-2;A0A3B3IT59;Q8N5Y2-6;Q8N5Y2-4;A0A3B3ITL5;A0A3B3ITF3;A0A3F2YNX2;A0A3B3IRN2;A0A3B3IU80;A0A3B3IUB0;A0A3B3IS72;A0A3B3ISB4;A0A3B3IRI6;A0A3B3ITV8;A0A3B3IRT2;A0A3B3ITF8;A0A3B3IT49;Q8N5Y2-5;A0A3B3ITX5 Q8N5Y2 MSL3 Male-specific lethal 3 homolog 1 LS(0.004)ES(0.032)S(0.387)AS(0.577)PQPK;LSESS(0.01)AS(0.989)PQPK 98.40700000000001 0.004988899999999999 48535000.0 88494.0 88584.0 119363.0 140841.0 130269.0 112418.0 111158.0 116568.0 115486.0 131200.0 True False 116633.25121045271 117217.0456454648 117780.16862960138 108372.28342175878 112183.39795661894 105388.48468862794 121050.84665842033 98555.09406615987 121590.35419065822 126606.7279341719 0.9212247493758403 0.925835834778155 0.9302836472548298 0.8559757067421097 0.8860776973475514 0.8324082488208984 0.9561170139501567 0.7784348878947631 0.9603783003844638 1.0 16.949994546654573 -8.512011693872525 24.617619538019646 1.000000023598316 0.8870182689763971 0.37489285961839247 0.050060509909787915 456.9463520914867 1035140.3968626267 0.0462099533685537 0.01193135861113893 3.0760139884529177e-09 8.512011693872525 -0.11298175462191884 LSESSAS(ph)PQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LSESSASPQPK 11 0 Q8N5Y2;Q8N5Y2-3;Q8N5Y2-2;A0A3B3IT59;Q8N5Y2-6;Q8N5Y2-4;A0A3B3ITL5;A0A3B3ITF3;A0A3F2YNX2;A0A3B3IRN2;A0A3B3IU80;A0A3B3IUB0;A0A3B3IS72;A0A3B3ISB4;A0A3B3IRI6;A0A3B3ITV8;A0A3B3IRT2;A0A3B3ITF8;A0A3B3IT49;Q8N5Y2-5;A0A3B3ITX5 Q8N5Y2 MSL3 Male-specific lethal 3 homolog 1 LSES(0.054)S(0.036)AS(0.911)PQPK;LSES(0.006)S(0.031)AS(0.963)PQPK;LSESS(0.002)AS(0.997)PQPK;LSES(0.025)S(0.141)AS(0.834)PQPK 152.38 9.900200000000001e-05 33276400.0 207109.0 219211.0 229977.0 271172.0 278689.0 255665.0 252225.0 236101.0 216184.0 175282.0 True False 242168.46311079044 240972.8193649714 235460.52387262892 255979.1119914864 224081.89103572615 242257.4773274903 228332.42204913526 229903.59891968808 219345.28202005342 207059.23906845192 1.1695612530998036 1.1637868488703755 1.1371650206576283 1.236260275769979 1.0822115064454898 1.1699911504427105 1.1027395979836023 1.1103276528688681 1.0593358838121676 1.0 17.659684052227227 -8.2241230289558 0.5251979453191538 0.9964020530788348 1.1708574461405243 0.6815225628672061 0.035907569575151066 0.4816466027574669 0.33192890333503705 0.03630877638255675 0.019316379397073244 5.968661796116643e-09 8.2241230289558 0.17445539306168956 LSESSAS(ph)PQPK ddPTM_PC-9_Lapatinib_30min_R1 2 LSESSASPQPK 11 0 Q8N5Y2;Q8N5Y2-3;Q8N5Y2-2;A0A3B3IT59;Q8N5Y2-6;Q8N5Y2-4;A0A3B3ITL5;A0A3B3ITF3;A0A3F2YNX2;A0A3B3IRN2;A0A3B3IU80;A0A3B3IUB0;A0A3B3IS72;A0A3B3ISB4;A0A3B3IRI6;A0A3B3ITV8;A0A3B3IRT2;A0A3B3ITF8;A0A3B3IT49;Q8N5Y2-5;A0A3B3ITX5 Q8N5Y2 MSL3 Male-specific lethal 3 homolog 1 LSESS(0.002)AS(0.998)PQPK;LSESS(0.002)AS(0.998)PQPK 190.66 0.00046872 50866000.0 408680.0 345680.0 355350.0 357100.0 345630.0 314980.0 293610.0 271900.0 318480.0 246040.0 True False 402852.1482572677 344879.59919851646 326134.49469066836 383362.3252506782 325300.7229347252 301509.0396542424 308811.6891552365 284533.4666197511 282609.4286569221 288567.68617230747 1.3960404007838894 1.1951428234157322 1.130183698031696 1.3285005342620644 1.1272943524954626 1.0448468560482114 1.0701533953834357 0.9860198499490083 0.9793523051925237 1.0 18.138550230228965 -6.61617146235293 0.6839816479073609 0.9749870544552124 1.2874125105128789 0.7216623267691105 0.07183738637859746 0.42520194597218364 0.44220569172732915 0.05280766878242181 0.0638454744684925 2.4200733970104906e-07 6.61617146235293 0.3124254560576665 LSFASETPLEKEPHS(ph)PADQPEQQAESTLTSAETR ddPTM_PC-9_AZD4547_30min_R2 3 LSFASETPLEKEPHSPADQPEQQAESTLTSAETR 34 1 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2 H3BSS6 ZNF106 Zinc finger protein 106 1 LSFAS(0.019)ET(0.019)PLEKEPHS(0.961)PADQPEQQAESTLTSAETR;LS(0.001)FAS(0.069)ET(0.053)PLEKEPHS(0.877)PADQPEQQAESTLTSAETR;LS(0.011)FAS(0.057)ET(0.057)PLEKEPHS(0.875)PADQPEQQAESTLTSAETR 79.068 1.3606e-08 35900900.0 43625.9 36499.2 64131.8 84779.7 71897.3 59795.1 52774.1 65691.8 52599.8 60603.0 True False 57498.028724908945 48296.85261924223 63281.37042902628 65235.049998307906 61915.600932734684 56056.10294441252 57470.8926630216 55540.64175738935 55380.118043380025 58481.30741611756 0.983186444786328 0.8258511095791871 1.082078585876242 1.115485492383657 1.0587246364411926 0.9585302624230209 0.9827224322139986 0.9497161436935017 0.946971271509521 1.0 15.835687944288242 -10.241586484403767 14.257599050098154 0.9999994400184514 0.9906737588038455 0.0014164399615955725 0.07776256191307693 0.0 0.0 0.0816529548208266 0.019803750433532642 5.7334168123396315e-11 10.241586484403767 -0.009325681214605974 LSFASETPLEKEPHS(ph)PADQPEQQAESTLTSAETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSFASETPLEKEPHSPADQPEQQAESTLTSAETR 34 1 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2 H3BSS6 ZNF106 Zinc finger protein 106 1 LSFAS(0.002)ET(0.002)PLEKEPHS(0.996)PADQPEQQAESTLTSAETR;LSFASETPLEKEPHS(1)PADQPEQQAESTLTSAETR 99.11399999999999 2.8282e-16 16452400.0 50428.0 30229.0 53294.0 57936.0 59455.0 58600.0 58829.0 59263.0 60401.0 46639.0 True False 58964.46440159996 33229.93534349877 54564.73107862048 54690.033751046314 47805.21955128863 55526.91284059575 53256.29123492344 57707.40904433883 61284.25035753454 55094.281505879175 1.0702465444677374 0.6031467229489647 0.9903882869004802 0.9926626186278567 0.8676983934564476 1.0078525633312854 0.9666391824937476 1.0474301046685 1.1123522928780698 1.0 15.749614962025555 -6.738955444326486 0.6500578966355524 1.0584479010315235 0.8628212675292085 0.1954625945826467 0.12182038402205839 1.1539377563975577 1.0715563528680745 0.09168178894708155 0.1002801812870117 1.8240828312691875e-07 6.738955444326486 -0.19562663350231502 LSFASETPLEKEPHS(ph)PADQPEQQAESTLTSAETR ddPTM_PC-9_Lapatinib_30min_R1 3 LSFASETPLEKEPHSPADQPEQQAESTLTSAETR 34 1 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2 H3BSS6 ZNF106 Zinc finger protein 106 1 LS(0.005)FAS(0.308)ET(0.105)PLEKEPHS(0.582)PADQPEQQAESTLTSAETR;LS(0.001)FAS(0.016)ET(0.016)PLEKEPHS(0.967)PADQPEQQAESTLTSAETR;LS(0.069)FAS(0.054)ET(0.059)PLEKEPHS(0.817)PADQPEQQAESTLTSAETR 77.876 1.6937e-08 18120800.0 59172.0 45172.3 56270.2 52743.6 52849.0 54869.9 47194.8 40228.6 54501.0 47818.0 True False 58328.19642918418 45067.70631472786 51643.8813652534 56622.540291491714 49740.52572513174 52523.24228498414 49638.315818070085 42097.76761772457 48362.52345902696 56083.277586520126 1.0400283103854049 0.803585458164451 0.9208427821569801 1.0096153921129103 0.8869047578112144 0.9365223386589008 0.8850822910892227 0.7506295892350443 0.8623341134871746 1.0 15.775283044512182 -7.521222938989732 24.958201335367768 0.8474603069197523 0.9264604287813798 0.08465218435010802 0.08335100306947825 118.3708335885256 1784308.553259353 0.036990690517776224 0.021757070039494685 3.0114597366590284e-08 7.521222938989732 0.07900012186162753 LSFQHDPETSVLVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSFQHDPETSVLVLR 15 0 F5H6X6;Q14697;Q14697-2;E9PKU7 F5H6X6 GANAB Neutral alpha-glucosidase AB 0 85.976 0.009585 0.0 10654.0 12284.0 15516.0 17029.0 17768.0 15836.0 16786.0 14335.0 15343.0 11652.0 False True 12457.51177390826 13503.474337872214 15885.960284757688 16074.920338762906 14286.48794865523 15005.532282315276 15195.908559884148 13958.721439187986 15567.362348895746 13764.415362818743 0.9050520087877638 0.9810423459283714 1.1541325850765727 1.1678607419960194 1.0379291507902864 1.090168516917116 1.1039995640448514 1.0141165513570678 1.1309860926565198 1.0 13.748655712979145 -5.044269121116101 4.480966657190838 1.0893815860786977 0.9178569032652321 0.5531233317934765 0.05380976924691509 0.13373109767070224 5.953543393402694 0.013769936623230483 0.04532355540200605 9.030896788573568e-06 5.044269121116101 -0.17152468281346567 LSFS(ph)PENILIQNQDIVR ddPTM_PC-9_AZD4547_30min_R2 2 LSFSPENILIQNQDIVR 17 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 LS(0.001)FS(0.999)PENILIQNQDIVR;LS(0.008)FS(0.992)PENILIQNQDIVR 210.57 9.2957e-18 126859000.0 119593.0 107644.0 153599.0 185723.0 171935.0 152700.0 123355.0 144162.0 115280.0 130590.0 True False 157621.0863110682 142437.8179068503 151562.17690019647 142907.43174174655 148064.79306413088 143151.64486072958 134333.35602970043 121885.0754131988 121373.46545121541 126018.08384850252 1.250781487048783 1.1302966491546356 1.202701804944144 1.1340232082369084 1.174948773559616 1.1359611294584104 1.0659847533564661 0.9672030528549191 0.9631432390063095 1.0 16.943271252658185 -7.419139384437143 1.7065426805442334 0.9697423484120543 1.1750025582128396 0.8677420661694217 0.03444882642646911 0.11958474062830483 0.6774844441648992 0.019578997637133777 0.010510630772193203 3.8094354202708415e-08 7.419139384437143 0.2052602098007853 LSFS(ph)PENILIQNQDIVR ddPTM_PC-9_Lapatinib_30min_R1 2 LSFSPENILIQNQDIVR 17 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 LSFS(1)PENILIQNQDIVR;LS(0.057)FS(0.943)PENILIQNQDIVR 181.86 9.533499999999999e-07 48808000.0 96923.6 73609.09 110818.9 77093.34 77587.09 102555.4 82246.6 90963.34 120778.3 89805.0 True False 95541.45169038881 73438.65267463395 101707.7978153247 82763.04139944336 73023.569908288 98169.34461031388 86504.92651229545 95189.82885439903 107174.97600211721 105327.67459235936 0.9070878291024147 0.6972398560858507 0.9656322349178945 0.7857672897436884 0.6932989851993301 0.9320375199609244 0.8212934240415735 0.9037494582767923 1.0175386138249733 1.0 16.684525025249314 -8.04477127795874 2.1029831980438276 1.0138306369290657 0.8244622752202617 0.4069027285297997 0.08598480620508504 0.32285220473733006 2.585476257914087 0.0712290260448724 0.023225533573948434 9.020460768679114e-09 8.04477127795874 -0.189368361708804 LSGDQPAART(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 LSGDQPAARTPR 12 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 LSGDQPAART(1)PR;LSGDQPAART(1)PR 95.094 0.0033905999999999997 12563500.0 51412.0 27476.0 74155.0 189083.0 155871.0 71839.0 49858.0 75404.0 55221.0 103194.0 True False 67759.9465639683 36357.07967753539 73171.65624798373 145492.8356532288 134231.00217930722 67346.89597347708 54295.26541225582 63752.04441154277 58139.86932409417 99581.20946980898 0.6804491221259144 0.36509980016418786 0.7347938093699083 1.4610470833590277 1.3479551302296982 0.6763012453056749 0.5452360510716338 0.6402015475707905 0.5838437756846186 1.0 16.60358591740269 -10.901252845717403 3.6896269930180727 1.001058824420161 0.7904534517984799 0.03711498356754872 0.3309160181216442 549094019.1918085 733036971.6021618 6061021.6970056435 0.09382106599010184 1.2552989174104967e-11 10.901252845717403 -0.2106053726216811 LSGDQPAART(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 LSGDQPAARTPR 12 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 LSGDQPAART(1)PR 76.358 0.01351 3531200.0 64524.0 22069.0 46369.0 38140.0 28651.0 24353.0 16505.0 15048.0 36066.0 17686.0 True False 63603.87592774757 22017.90058641533 42556.71980951616 40944.942831310254 26965.804510033286 23311.478959615728 17359.548140414758 15747.185015424842 32003.86728818306 20743.001534886334 3.0662812139687814 1.061461647649441 2.0516182162905747 1.9739160102961744 1.2999953003272557 1.1238238072927698 0.8368869910759462 0.7591565275131785 1.5428754240006102 1.0 14.340337048347692 -6.39781197274161 2.409873818717666 1.022948505180403 1.9826239041566152 0.47306443010717336 0.491704165224321 0.27664562917013674 3.1473458350731622 0.1625905126067314 0.18884240007935021 4.001179428346313e-07 6.39781197274161 0.9596753989762121 LSGEMPPAS(ph)PSFPR ddPTM_PC-9_AZD4547_30min_R2 1 LSGEMPPASPSFPR 14 0 Q96JM7-2;Q96JM7 Q96JM7-2 L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 1 LSGEMPPAS(0.747)PS(0.253)FPR 106.42 0.00077253 7434400.0 38433.0 36372.0 45804.0 64237.0 54789.0 50798.0 32710.0 53352.0 40672.0 49407.0 True False 50653.89454393898 48128.537706773815 45196.60903219808 49428.1521017567 47182.49307698073 47621.593029700896 35621.12663233357 45107.674306994755 42821.83888646633 47677.27596832039 1.062432647737602 1.0094649228440247 0.94796961685121 1.0367234934856533 0.989622249147195 0.9988320864082819 0.7471300721123908 0.9461042685611268 0.8981603503295721 1.0 15.541014189609976 -7.047028686734024 24.99992704849195 0.8904464148023765 1.0060626747801522 0.3974936721241473 0.06593420168709671 394.559830404425 209742.38769927525 0.02408353192493492 0.018655563203885513 8.973695180144641e-08 7.047028686734024 0.11561625997777569 LSGEMPPAS(ph)PSFPR ddPTM_PC-9_Lapatinib_30min_R1 2 LSGEMPPASPSFPR 14 0 Q96JM7-2;Q96JM7 Q96JM7-2 L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 1 LSGEMPPAS(0.5)PS(0.5)FPR;LSGEMPPAS(0.987)PS(0.013)FPR 121.24 0.0012252 14543000.0 107609.0 104995.0 120704.0 104772.0 115369.0 119967.0 108409.0 102815.0 133720.0 83123.0 True False 106074.47592692602 104751.89052837373 110780.1830509141 112477.28238914604 108583.22224418087 114836.29106673581 114021.88757068926 107592.16024461103 118659.04546597469 97490.69979556484 1.0880471280784845 1.0744808555896654 1.1363153950399056 1.153723202572221 1.1137803141415203 1.1779204714659364 1.1695668182687153 1.1036146060109187 1.2171319491479624 1.0 16.572976977911416 -5.284581225112849 7.592643728190544 1.140605170227441 1.0812091132383292 0.11953950959076876 0.05497858657483791 0.31604287298391215 86.26112264623438 0.013196631052105235 0.028748658224615215 5.1930054082061155e-06 5.284581225112849 -0.059396056989111656 LSGEMPPASPS(ph)FPR ddPTM_PC-9_AZD4547_30min_R2 1 LSGEMPPASPSFPR 14 0 Q96JM7-2;Q96JM7 Q96JM7-2 L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 1 LS(0.001)GEMPPAS(0.235)PS(0.764)FPR 111.66 0.00033306 6176300.0 28388.0 25400.0 38138.0 48274.0 45636.0 31141.0 29848.0 43671.0 37504.0 35443.0 True False 37414.79349291855 33610.053275928025 37632.26520107349 37145.17512586519 39300.229134700254 29193.748347137986 32504.414176762246 36922.65040974598 39486.38487406653 34202.151358009585 1.0939309957809604 0.9826882795797317 1.100289417679003 1.086047913683839 1.1490572251823212 0.8535646790622511 0.950361684460245 1.0795417523084931 1.1545000330752428 1.0 15.061799454833563 LSGEMPPASPS(ph)FPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSGEMPPASPSFPR 14 0 Q96JM7-2;Q96JM7 Q96JM7-2 L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 1 LSGEMPPAS(0.029)PS(0.971)FPR 107.11 0.00071535 8792100.0 25972.0 29399.0 35490.0 33580.0 42997.0 30158.0 31801.0 33984.0 32126.0 27858.0 True False 30368.54662961754 32317.538428777712 36336.2161965745 31698.621467828903 34572.04650654709 28576.4613898752 28788.579060697957 33091.95600902436 32595.78197357916 32908.43487619332 0.9228195368108134 0.9820442251465725 1.1041611773175184 0.9632369812506756 1.0505527423778291 0.8683628224005279 0.8748085154765061 1.005576720178929 0.9904993080409199 1.0 15.006169793126615 -6.742495682565532 24.999325233267356 0.9436329194362294 1.006549229402909 0.1635645001208007 0.06369038944868542 444.2680544972247 586283.6657639138 0.021921523095432004 0.0218879551970809 1.80927389662708e-07 6.742495682565532 0.06291630996667963 LSGEMPPASPS(ph)FPR ddPTM_PC-9_Lapatinib_30min_R1 1 LSGEMPPASPSFPR 14 0 Q96JM7-2;Q96JM7 Q96JM7-2 L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 1 LSGEMPPAS(0.079)PS(0.921)FPR 76.282 0.014518999999999999 17217000.0 55390.0 69233.0 75265.0 64326.0 60336.0 62618.0 55504.0 67772.0 76691.0 60650.0 True False 54600.12844271801 69072.695242163 69077.00223130174 69056.74862524551 56787.15510514006 59939.974109687384 58377.72553684221 70920.93453384984 68053.25198796784 71133.27168895486 0.7675751043965545 0.9710321710520758 0.9710927192180251 0.9708079916134129 0.798320585526472 0.8426432903548635 0.8206810139720699 0.9970149390002261 0.9567007164459544 1.0 16.118236899633228 -7.7802620269246106 24.985238534090076 0.9826434243882837 0.8838598180433048 0.320403039034286 0.07104848378893781 354.26419150588777 470244.4969602184 0.041508514185067895 0.019993426290733154 1.6585859154494487e-08 7.7802620269246106 -0.09878360634497885 LSGFS(ph)FK ddPTM_PC-9_AZD4547_30min_R2 2 LSGFSFK 7 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 LS(0.011)GFS(0.989)FK;LS(0.08)GFS(0.92)FK 83.99799999999999 0.02025 523750000.0 409350.0 464330.0 444560.0 412250.0 485290.0 451510.0 463610.0 568980.0 547320.0 415790.0 True False 539514.784991059 614415.5920319556 438664.84392965573 317212.1316990086 417915.86021515226 423277.00832395576 504870.3918684236 481057.21485968446 576250.2178240736 401233.3186566265 1.3446410352894274 1.5313174740549635 1.0932911688350162 0.790592697438662 1.0415781561072264 1.054939828379991 1.2582962789799848 1.1989463299566376 1.4361973221800797 1.0 18.614081887627194 -5.270299552875334 24.31298627199558 1.1059242205347832 1.4379792575837818 0.3851350694809591 0.1661108292621268 424.26468434862886 1164218.2840571362 0.046999540895903906 0.10030917651297978 5.366615085616694e-06 5.270299552875334 0.3320550370489985 LSGFS(ph)FK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSGFSFK 7 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 LSGFS(1)FK;LS(0.003)GFS(0.997)FK 129.42 0.0044245 516910000.0 252534.0 316077.0 243936.0 176175.0 207805.0 147021.0 148081.0 178030.0 124488.0 88838.0 True False 295283.01842614566 347455.0356798798 249752.35937243188 166304.48591705627 167087.10199067424 139310.95994432134 134053.69566640063 173356.90113837746 126308.40149184199 104943.62615877883 2.813729897034289 3.310873164933173 2.3798716369354214 1.584703063961588 1.5921605542567479 1.3274837647933473 1.2773876849231272 1.65190500351198 1.2035833534162277 1.0 16.679255020405954 -5.635291717743723 2.1342416273575866 1.3765046010147528 3.0786511784889052 0.9116421198717817 0.21534194842100865 0.07854923098525683 0.7202752018760903 0.06031147081477834 0.13205116804949169 2.3158385672345673e-06 5.635291717743723 1.7021465774741524 up LSGFS(ph)FK ddPTM_PC-9_Lapatinib_30min_R1 2 LSGFSFK 7 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 LS(0.002)GFS(0.998)FK;LS(0.006)GFS(0.994)FK 87.30799999999999 0.018029 378300000.0 178304.0 235530.0 213690.0 211450.0 213630.0 148594.0 183034.0 205350.0 190787.0 189921.0 True False 175761.35226305109 234984.64475592002 196121.2330672538 227000.7383765224 201064.70341273968 142238.98100953226 192510.60492775973 214891.31066703115 169298.55898382346 222748.59179617494 0.7890570748203908 1.054932122627925 0.8804600356203985 1.0190894431522979 0.9026530843199359 0.6385628742366524 0.8642506036757156 0.9647257876434364 0.7600432290891397 1.0 17.765056785577514 -6.531533978686067 24.999541399427585 0.8362744481213888 0.9429844448931464 0.11642918026361748 0.11615365847388177 365.9748641088903 1057063.3678832876 0.03713453693360005 0.03719020036034993 2.9408035997545005e-07 6.531533978686067 0.10670999677175752 LSGFS(ph)FKK ddPTM_PC-9_AZD4547_30min_R2 2 LSGFSFKK 8 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 LS(0.002)GFS(0.998)FKK;LS(0.016)GFS(0.984)FKK 110.54 0.005524 784700000.0 1460690.0 1328250.0 1509090.0 2171840.0 2568100.0 2080200.0 1708230.0 2245700.0 1844490.0 1900630.0 True False 1925159.035760576 1757580.8371555666 1489078.4805781096 1671155.8425935102 2211563.6436327393 1950124.7651557883 1860259.1607199959 1898678.6660522255 1941985.975799035 1834089.5222067514 1.0496537995834854 0.9582851959379112 0.8118897483185394 0.9111637258484517 1.20581008552506 1.0632658556434176 1.0142684630146939 1.035215916706051 1.0588283463189212 1.0 20.80663262815446 -6.199574690731563 24.999333166816864 1.062246346805213 0.9259392984452532 0.4147205857231645 0.07556956549993916 234.83497050718933 94895.60463840177 0.02336509431445268 0.030164198722294505 6.315755504687435e-07 6.199574690731563 -0.13630704835995977 LSGFS(ph)FKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSGFSFKK 8 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 LS(0.117)GFS(0.883)FKK 97.81299999999999 0.008370299999999999 425400000.0 1244800.0 791600.0 1000600.0 993800.0 1188900.0 978960.0 846120.0 1042100.0 751910.0 562770.0 True False 1455520.054079311 870184.8164978544 1024458.0987966325 938120.6079430733 955943.5795900603 927621.6142394135 765969.3882216831 1014745.979196218 762905.261276035 664795.7461151318 2.1894244398899008 1.3089506387231795 1.54101181420498 1.4111411112739072 1.437950806960348 1.3953483000758622 1.1521875594087054 1.5264026358864224 1.1475784340291375 1.0 19.342551625079608 -3.073154044381083 1.6315697943532346 1.340003973988086 199.99979521414627 0.6822943613741219 0.1739898725900557 181.19908830618402 2.677896254575969 0.04488032369031765 132951.48740358054 0.0008449790776710482 3.073154044381083 198.6597912401582 LSGFS(ph)FKK ddPTM_PC-9_Lapatinib_30min_R1 2 LSGFSFKK 8 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 LS(0.346)GFS(0.654)FKK;LS(0.454)GFS(0.546)FKK 104.82 0.0056585 898230000.0 2483600.0 1853430.0 1994440.0 2069320.0 1445560.0 1453060.0 1205800.0 1605210.0 2026290.0 1421830.0 True False 2448183.4085635375 1849138.496709403 1830464.8419610395 2221504.6958491593 1360535.002880307 1390916.0110482988 1268230.423975286 1679793.9167072142 1798067.8824203543 1667591.4210306106 1.4680954685234004 1.1088678398013059 1.0976698601806008 1.3321636630129803 0.8158683150573325 0.8340868113777415 0.760516279935939 1.0073174373067129 1.0782424637979404 1.0 20.669334424618356 -6.26282976225506 24.995154309590177 0.9045007180033534 1.2304948755931235 0.5945756948205544 0.1351477580855218 95.17721708908859 1711018.906167783 0.042726123496579574 0.05112114710272347 5.459718329543305e-07 6.26282976225506 0.32599415758977013 LSGINEIPRPFS(ph)PPVT(ph)SNTSPPPAAPLAR ddPTM_PC-9_Lapatinib_30min_R1 1 LSGINEIPRPFSPPVTSNTSPPPAAPLAR 29 1 Q0JRZ9-3;Q0JRZ9 Q0JRZ9-3 FCHO2 F-BAR domain only protein 2 2 LS(0.001)GINEIPRPFS(0.981)PPVT(0.354)S(0.315)NT(0.122)S(0.227)PPPAAPLAR 52.183 0.029913 6908500.0 13858.0 11172.0 12662.0 9555.4 11974.0 13918.0 9976.3 10620.0 13935.0 11153.0 True False 13660.382378754039 11146.131920405638 11620.979236733454 10258.135991879963 11269.712861789758 13322.75958444265 10492.823999589209 11113.443970216096 12365.493557944632 13080.78118956164 1.0443093711906837 0.8520998676516479 0.8884010112489997 0.7842143250638482 0.8615473876119035 1.018498772464301 0.8021557617646261 0.8496009381369773 0.9453176670986744 1.0 13.67516108129163 LSGINEIPRPFS(ph)PPVTSNT(ph)SPPPAAPLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSGINEIPRPFSPPVTSNTSPPPAAPLAR 29 1 Q0JRZ9-3;Q0JRZ9 Q0JRZ9-3 FCHO2 F-BAR domain only protein 2 2 LSGINEIPRPFS(0.842)PPVT(0.218)S(0.218)NT(0.707)S(0.015)PPPAAPLAR 95.209 5.32e-10 5940100.0 16363.0 14961.0 19060.0 15568.0 20353.0 19996.0 19440.0 20969.0 20107.0 13939.0 True False 19132.93271601849 16446.229206195545 19514.462685452534 14695.775432136996 16364.975755233 18947.374559053802 17598.502466588114 20418.58596849201 20401.026836293222 16466.030358936703 1.16196389165737 0.9987974543767064 1.1851346232251623 0.8924904856719806 0.9938628435936985 1.150694742207273 1.0687762674406085 1.2400430172540107 1.238976631985915 1.0 14.007205170694299 -7.223019535611619 1.860389612008443 1.168486507279439 1.0475767448204303 0.12615612579934288 0.1056139360338886 0.5957083133400741 4.031407870193216 0.053644855386972785 0.034654404342649554 5.983846776711501e-08 7.223019535611619 -0.12090976245900875 LSGINEIPRPFS(ph)PPVTSNTS(ph)PPPAAPLAR ddPTM_PC-9_Lapatinib_30min_R1 1 LSGINEIPRPFSPPVTSNTSPPPAAPLAR 29 1 Q0JRZ9-3;Q0JRZ9 Q0JRZ9-3 FCHO2 F-BAR domain only protein 2 2 LSGINEIPRPFS(0.981)PPVT(0.064)S(0.132)NT(0.253)S(0.57)PPPAAPLAR 71.523 0.0021087 0.0 9422.6 7400.4 7145.4 8595.0 8167.8 8205.3 8071.5 8553.8 9458.0 6096.5 True False 9288.231996106786 7383.264828479216 6557.932794041639 9227.104972079485 7687.386062512645 7854.3784464885175 8489.40277584718 8951.240775182152 8392.74044284466 7150.271901924373 1.299004027190493 1.0325851841371425 0.9171585198426767 1.2904551181607749 1.0751180050151263 1.0984726950557846 1.187283909240207 1.2518741801655233 1.1737652159193972 1.0 12.803782388664917 -7.2614366589756 23.255903473704077 1.1742203431762062 1.1115317024065323 0.005108474424100895 0.12215693027474032 0.345262802641024 2737035.6144820843 0.04847313412361797 0.03508232424814725 5.477259799293584e-08 7.2614366589756 -0.06268864076967384 LSGINEIPRPFS(ph)PPVTSNTSPPPAAPLAR ddPTM_PC-9_AZD4547_30min_R2 2 LSGINEIPRPFSPPVTSNTSPPPAAPLAR 29 1 Q0JRZ9-3;Q0JRZ9 Q0JRZ9-3 FCHO2 F-BAR domain only protein 2 1 LSGINEIPRPFS(1)PPVTSNTSPPPAAPLAR;LSGINEIPRPFS(0.986)PPVT(0.004)S(0.004)NT(0.003)S(0.003)PPPAAPLAR 142.09 3.9026e-11 140077000.0 78686.0 83756.0 116502.0 156591.0 133529.0 122007.0 100912.0 144341.0 133044.0 115547.0 True False 103706.5112295263 110828.48906215075 114957.10735894542 120491.36425683307 114990.80322831485 114377.88300277008 109892.97250755242 122036.41507620945 140076.4342252907 111501.73469976983 0.9300887695493438 0.993962016470579 1.0309894071915522 1.0806232260087143 1.0312916075964171 1.0257946507356552 0.9855718640023926 1.0944799684489694 1.2562713450374674 1.0 16.7667066296343 -7.94485521796246 5.60383286827096 1.143193675359591 1.0160543473279535 0.3338657002319243 0.06849431109104245 0.18708094061138902 12.287709279367466 0.037790636488947406 0.017448568999865893 1.1353892606672852e-08 7.94485521796246 -0.12713932803163752 LSGINEIPRPFS(ph)PPVTSNTSPPPAAPLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSGINEIPRPFSPPVTSNTSPPPAAPLAR 29 1 Q0JRZ9-3;Q0JRZ9 Q0JRZ9-3 FCHO2 F-BAR domain only protein 2 1 LSGINEIPRPFS(0.979)PPVT(0.014)S(0.005)NT(0.002)SPPPAAPLAR;LSGINEIPRPFS(0.999)PPVT(0.001)SNTSPPPAAPLAR 143.03 4.2720999999999997e-14 85000000.0 106592.0 117187.0 108865.0 128987.0 152638.0 130318.0 145916.0 129609.0 120490.0 117422.0 True False 124635.9203120356 128820.55089809792 111460.75447281153 121760.27657149649 122729.67962105085 123483.8946682724 132093.78013964364 126206.90108208703 122251.93830531534 138709.67908795955 0.8985380193475944 0.928706286000484 0.8035542667655604 0.8778066344907699 0.8847953540662772 0.8902327182947913 0.9523039848998527 0.9098636945303279 0.8813511725291505 1.0 17.0817089361069 -7.087181699350883 5.076082253442616 0.9282101582530397 0.878048904132974 0.2989652514463651 0.041064332331778475 0.3353936295969519 14.408189694660651 0.01602258809414643 0.012434464409625912 8.181224319184427e-08 7.087181699350883 -0.05016125412006567 LSGINEIPRPFS(ph)PPVTSNTSPPPAAPLAR ddPTM_PC-9_Lapatinib_30min_R1 2 LSGINEIPRPFSPPVTSNTSPPPAAPLAR 29 1 Q0JRZ9-3;Q0JRZ9 Q0JRZ9-3 FCHO2 F-BAR domain only protein 2 1 LSGINEIPRPFS(0.995)PPVT(0.003)S(0.001)NTSPPPAAPLAR;LSGINEIPRPFS(0.998)PPVT(0.002)S(0.001)NTSPPPAAPLAR 107.95 9.4853e-12 105285000.0 139091.0 123290.0 143207.0 124519.0 119308.0 129688.0 110216.0 125114.0 147969.0 117059.0 True False 137107.53683383463 123004.52957991473 131433.073255006 133676.54264320683 112290.53800855283 124141.54655749383 115922.44518897017 130927.25319111244 131303.17303735262 137292.49217868713 0.9986528371514171 0.8959304884627156 0.9573216362329918 0.9736624379228683 0.8178927793255142 0.9042122011735554 0.8443465724119591 0.9536373847792763 0.9563754794869674 1.0 17.06689320849626 -8.32395062950605 2.1286798252645642 0.9939725771165699 0.912852001588269 0.19623362330715544 0.053228796541881444 0.49546207031274303 4.279046155174838 0.05115618986438145 0.014600417474190438 4.742959000413757e-09 8.32395062950605 -0.08112057552830099 LSGLAAPDYTRLS(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 1 LSGLAAPDYTRLSPAK 16 1 Q8TEK3-1;Q8TEK3 Q8TEK3-1 DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 1 LSGLAAPDY(0.009)T(0.041)RLS(0.95)PAK 65.374 0.01348 13999000.0 52029.0 41895.0 60048.0 68239.0 65537.0 58264.0 52098.0 57977.0 45893.0 57889.0 True False 68573.13972957093 55436.739448622226 59251.724285333825 52507.55283204041 56438.31880096524 54620.74286945342 56734.62107280084 49017.9868289218 48318.81028758359 55862.32373004024 1.2275382610461545 0.9923815506946204 1.0606741776742616 0.9399457331167951 1.0103109758503521 0.9777742711422662 1.015615128131369 0.8774784784429248 0.8649624122528207 1.0 15.76958796684576 -1.5228787452803376 0.7211928493978018 0.9522399824628109 37.5779356079927 0.6434437540900813 0.057615239811366036 212.78772295876075 1.036100440478622 0.02271955088785959 12610.115771312665 0.029999999999999995 1.5228787452803376 36.625695625529886 LSGLAAPDYTRLS(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 1 LSGLAAPDYTRLSPAK 16 1 Q8TEK3-1;Q8TEK3 Q8TEK3-1 DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 1 LSGLAAPDY(0.001)T(0.075)RLS(0.924)PAK 68.08800000000001 0.011251 9109200.0 87744.0 57964.0 64200.0 65689.0 75421.0 55617.0 51172.0 54819.0 64980.0 58120.0 True False 86492.75446972091 57829.78791929755 58921.723819166626 70519.98819208019 70984.88506339122 53238.39055955934 53821.43577348105 57366.090866598504 57661.26813026499 68165.96455996804 1.2688554328844 0.848367485043399 0.864386269592519 1.0345337097084752 1.0413537829563504 0.7810113287947921 0.7895646474148019 0.8415650132278478 0.845895286635874 1.0 16.056763957258198 -6.759008662437706 24.975852327598847 0.8378274003438815 0.9955432031472305 0.2926405701750351 0.12211375202767032 85.36955882030807 877183.26164639 0.041066191086393436 0.039246836633959205 1.7417721316583178e-07 6.759008662437706 0.15771580280334907 LSGLS(ph)FK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSGLSFK 7 0 P49006 P49006 MARCKSL1 MARCKS-related protein 1 LSGLS(1)FK 83.948 0.020284 3024000.0 35249.0 43741.0 32103.0 27517.0 37293.0 26017.0 28879.0 25546.0 21470.0 16500.0 True False 41215.959500515506 48083.31740580173 32868.45727130549 25975.311701317656 29985.7043600405 24652.622719689072 26143.37205414598 24875.44456822438 21783.958132750548 19491.31938607188 2.1145802746410096 2.4669093175991534 1.686312589736365 1.332660513473455 1.5384132682915097 1.2648001005670946 1.3412828314140464 1.2762319510294358 1.1176235790542197 1.0 14.250544130859339 -5.4919335285508675 2.7391521994580827 1.291042451069783 2.293936074220167 0.8632566035411453 0.16125823714651547 0.08866655949677672 1.3148514027671918 0.044188012237164384 0.10156108314907832 3.2215618334597243e-06 5.4919335285508675 1.0028936231503838 up LSGLS(ph)FK ddPTM_PC-9_Lapatinib_30min_R1 2 LSGLSFK 7 0 P49006 P49006 MARCKSL1 MARCKS-related protein 1 LS(0.001)GLS(0.999)FK;LSGLS(1)FK 111.06 0.012596 111207400.0 136120.0 184796.0 153961.0 169017.0 183670.0 131555.0 157085.0 177254.0 159182.0 157749.0 True False 134178.9038386494 184368.11621583262 141302.92088664658 181447.07400418364 172866.8917091136 125928.69931968318 165218.0926771918 185489.86793754084 141253.24689922808 185015.70446267052 0.7252298080767616 0.9964998201167914 0.7637347396915509 0.9807117429904071 0.93433631599631 0.6806378933367304 0.8929949657896573 1.0025628282542145 0.7634662544428917 1.0 17.497288208901722 -10.98397096531847 3.0557156089573856 1.002998894975487 0.8668235708922792 0.11737428988621623 0.11378859654193874 43135793.956188664 50009880.2964155 1097452.804149451 0.027409803378858354 1.0375977819172544e-11 10.98397096531847 -0.13617532408320787 LSGLS(ph)FKR ddPTM_PC-9_Lapatinib_30min_R1 1 LSGLSFKR 8 1 P49006 P49006 MARCKSL1 MARCKS-related protein 1 LSGLS(1)FKR 60.102 0.032604 450940000.0 380100.0 233560.0 319000.0 276860.0 280140.0 204820.0 167410.0 182190.0 282010.0 195320.0 True False 374679.70429819747 233019.20616988378 292773.0513756105 297221.2079778858 263662.7159764307 196060.3260587401 176077.6706565789 190655.2125172947 250247.0641030475 229080.80175245972 1.6355788063945624 1.0171922063625385 1.2780339912201608 1.297451404500746 1.1509594604149305 0.8558566434152743 0.7686269181423812 0.8322618528431424 1.092396491494122 1.0 17.80549703226282 -6.6093095286890495 3.4708699453378697 0.8905693911621977 1.2806701258251911 0.5637480080729836 0.16414620885692574 0.17945339222075518 4.287073569125255 0.055464353615930655 0.05589229707110404 2.458614685173907e-07 6.6093095286890495 0.39010073466299344 LSGLSFKR ddPTM_PC-9_Lapatinib_30min_R1 1 LSGLSFKR 8 1 P49006 P49006 MARCKSL1 MARCKS-related protein 0 79.71300000000001 0.044216000000000005 0.0 13220.0 7191.5 10187.0 9942.1 10752.0 5859.9 7601.4 8571.6 11555.0 7617.0 False True 13031.480375748917 7174.848523594445 9349.464182957172 10673.275199873351 10119.588499245321 5609.285737094084 7994.963298064153 8969.867828164246 10253.554220455706 8933.588300985479 1.458706170096443 0.8031317631687791 1.0465519417237772 1.194735512794558 1.1327574271727983 0.6278871991980327 0.8949330357189412 1.004061025195751 1.147753161999263 1.0 13.125024055106655 -4.747540205647557 24.865025448517958 0.983011239589144 1.4587074469175512 0.4336515773690415 0.16290724117989755 700.1870752485344 1252527.5094767795 0.04308265646991208 0.8643630868926063 1.788379958727085e-05 4.747540205647557 0.4756962073284071 LSGNTHYTPLCAPT(ph)SPNK ddPTM_PC-9_AZD4547_30min_R2 1 LSGNTHYTPLCAPTSPNK 18 0 Q4AC94;Q4AC94-2;Q4AC94-4;Q4AC94-1;Q4AC94-3 Q4AC94 C2CD3 C2 domain-containing protein 3 1 LSGNTHYTPLCAPT(0.85)S(0.15)PNK 123.58 0.00045625 0.0 10097.0 11740.0 32178.0 49567.0 38200.0 40619.0 28638.0 46380.0 28169.0 41017.0 True False 13307.635969353194 15534.725411787196 31751.29869526831 38140.09395251606 32896.58937999712 38079.08750882755 31186.72652084282 39213.036706373096 29657.955831846724 39581.00731460314 0.33621266542257583 0.392479284024077 0.8021852107728922 0.9635958390185924 0.8311205704929129 0.962054533027979 0.7879214966147841 0.9907033541287796 0.7492976516771119 1.0 15.272520708187786 -5.286202573695013 3.2808563054152446 0.892703251333947 0.342187269390978 0.869082649611271 0.08177992669748248 0.06942419332869673 1.538442841300505 0.019850797180393134 0.05369905274414695 5.173654540777745e-06 5.286202573695013 -0.550515981942969 down LSGPS(ph)LK ddPTM_PC-9_Lapatinib_30min_R1 1 LSGPSLK 7 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 LS(0.003)GPS(0.997)LK 73.985 0.034872 6755000.0 79121.0 60174.0 53931.0 96238.0 42306.0 18486.0 23000.0 28141.0 51882.0 49195.0 True False 77992.72003098544 60034.67080007951 49497.00135968032 103315.66356055668 39817.644256796186 17695.396872970734 24190.827460135675 29448.533593771273 46038.50281831961 57698.29020178296 1.351733643375369 1.0404930647013237 0.8578590663012539 1.7906191535180722 0.6901009391707376 0.30668840984864953 0.419264199606874 0.5103883233070444 0.7979179739523192 1.0 15.816240947051803 -6.498018078523056 24.119476038883914 0.5571787766485802 1.2188243389198545 0.5339928049712113 0.29063952974925167 365.83283494061175 354926.23190905235 0.0888063905040521 0.10017993269948973 3.17674182859249e-07 6.498018078523056 0.6616455622712744 LSGS(ph)RQDLIPSYSLGSNK ddPTM_PC-9_AZD4547_30min_R2 2 LSGSRQDLIPSYSLGSNK 18 1 Q9NQT8;H0YBA8 Q9NQT8 KIF13B Kinesin-like protein KIF13B 1 LS(0.056)GS(0.944)RQDLIPSYSLGSNK;LS(0.039)GS(0.961)RQDLIPSYSLGSNK 89.04299999999999 0.00069839 32372000.0 54203.0 56272.0 83003.0 138615.0 128487.0 103561.0 72927.0 92700.0 73423.0 88126.0 True False 71438.42650756169 74460.82354106382 81902.3259868033 106659.45333040158 110648.79789705982 97085.31429876883 79417.36172168126 78375.34503408328 77303.9898839746 85040.73556346675 0.8400494896266093 0.8755900692497298 0.963095220709595 1.2542160251048224 1.3011270088848363 1.1416330498025042 0.9338743508681353 0.9216212032360771 0.9090230625566716 1.0 16.37586645512468 -10.9199606756927 4.380801675884057 0.9999454581442516 1.0238778049404198 0.0 0.15330178904596495 9.382873841434869e-05 1.291346846651268e-05 0.17054419515969657 0.041268783080764954 1.2023733016617377e-11 10.9199606756927 0.02393234679616818 LSGS(ph)RQDLIPSYSLGSNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSGSRQDLIPSYSLGSNK 18 1 Q9NQT8;H0YBA8 Q9NQT8 KIF13B Kinesin-like protein KIF13B 1 LS(0.226)GS(0.774)RQDLIPSYSLGSNK 68.26100000000001 0.0057383 11377000.0 44688.0 30817.0 48211.0 54890.0 55867.0 49837.0 45594.0 41404.0 49190.0 39248.0 True False 52252.795771767655 33876.30809754216 49360.53308123564 51814.69125578104 44920.262394615136 47223.45998697563 41275.006248025624 40317.18887116425 49909.31069166277 46363.35171300292 1.127028004688302 0.7306699547358505 1.0646454852269047 1.1175786335837592 0.9688743530165645 1.0185514688260013 0.8902506985156072 0.869591765512005 1.0764819377298247 1.0 15.500697245396399 -7.2271232760405075 24.811950446700617 0.9482136934254882 0.9983550976848169 0.030207606846437196 0.11695016579214669 2272.7082887704737 1643263.537744525 0.04467874264168168 0.03460551653637303 5.9275704449256136e-08 7.2271232760405075 0.05014140425932867 LSGS(ph)RQDLIPSYSLGSNK ddPTM_PC-9_Lapatinib_30min_R1 2 LSGSRQDLIPSYSLGSNK 18 1 Q9NQT8;H0YBA8 Q9NQT8 KIF13B Kinesin-like protein KIF13B 1 LS(0.118)GS(0.878)RQDLIPS(0.002)Y(0.001)S(0.001)LGSNK;LS(0.165)GS(0.835)RQDLIPSYSLGSNK 128.38 2.0085e-05 24128000.0 71920.0 47975.0 70198.0 66663.0 48036.0 53107.0 39512.0 35971.0 52704.0 44447.0 True False 70894.40761148746 47863.91683507519 64426.59141211618 71565.61940124886 45210.61692240965 50835.73740846353 41557.738026299194 37642.34397859165 46767.920522275854 52129.60472809528 1.3599644190909985 0.9181714897845544 1.2358925748269376 1.3728402464306146 0.8672733499174868 0.9751797979980766 0.7972003287395277 0.7220914905250431 0.8971470389275801 1.0 15.66981530031248 -6.282361753753659 23.92878504597797 0.8635573199042011 1.2010478574578662 0.595282763401362 0.1387927951733483 336.4760365594839 384824.20364647615 0.04363048420793665 0.049532636427854194 5.219612304507772e-07 6.282361753753659 0.3374905375536651 LSGSNPYTTVTPQIINSK ddPTM_PC-9_Lapatinib_30min_R1 1 LSGSNPYTTVTPQIINSK 18 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 171.08 2.7881e-07 10315000.0 49366.0 47798.0 49682.0 50838.0 51492.0 44620.0 46681.0 44308.0 45955.0 49144.0 False True 48662.03178738435 47687.326667700385 45597.337738066 54576.79611059652 48463.34179716704 42711.70661430024 49097.913768112805 46366.711434306475 40779.06397239654 57638.47491973618 0.8442630006284539 0.8273523325193257 0.7910920231939181 0.9468813355418726 0.84081582423293 0.7410277019608508 0.8518253447282143 0.8044402892143473 0.7074972755469845 1.0 15.814744542701915 -6.5410708426075805 24.965082329795653 0.8084711666199672 0.8521817434745143 0.021244707192103696 0.08167168857711139 745.000862861405 1022359.6175374077 0.025777568046786537 0.025781076218236488 2.876929088528123e-07 6.5410708426075805 0.043710576854547045 LSGT(ph)IECEGPNR ddPTM_PC-9_Lapatinib_30min_R1 1 LSGTIECEGPNR 12 0 Q9NTI2;F8W9B3;F8VRS1;Q9NTI2-3;Q9NTI2-1 Q9NTI2 ATP8A2 Phospholipid-transporting ATPase IB;Phospholipid-transporting ATPase 1 LS(0.004)GT(0.996)IECEGPNR 76.533 0.045357999999999996 3605700.0 4725.5 7825.0 18039.0 13458.0 13106.0 11652.0 9048.1 9015.8 13684.0 11346.0 True False 4658.113503449434 7806.881693266569 16555.903052553695 14447.746214571916 12335.130847387396 11153.671122138641 9516.566345306686 9434.706981796064 12142.76382109181 13307.140982405308 0.35004615263401717 0.586668594222367 1.2441367439064408 1.085713770799807 0.9269557498261194 0.8381718610245444 0.7151473301357131 0.7089957936322029 0.9124998252552493 1.0 13.69991302340891 -5.033845619013818 6.936940703841975 0.9141302173256773 0.4041421965690086 0.6052861337216552 0.15376452070151808 0.12884491930303005 21.397420375343344 0.044162933899921285 0.1273242908995209 9.250269397827283e-06 5.033845619013818 -0.5099880207566687 LSIGES(ph)ITNR ddPTM_PC-9_AZD4547_30min_R2 4 LSIGESITNR 10 0 O60296 O60296 TRAK2 Trafficking kinesin-binding protein 2 1 LS(0.018)IGES(0.974)IT(0.008)NR;LS(0.015)IGES(0.936)IT(0.049)NR;LS(0.082)IGES(0.832)IT(0.086)NR;LS(0.021)IGES(0.97)IT(0.009)NR 68.846 0.022626 192060000.0 1063160.0 1010020.0 1855140.0 2799720.0 2402720.0 1985840.0 1506440.0 2253310.0 1503510.0 1957040.0 True False 1401222.7648982408 1336489.2129823938 1830539.6314730558 2154287.8092428097 2069143.8019661407 1861665.110872501 1640510.241639028 1905112.7154126256 1582982.469123501 1888524.6252766147 0.7419669016457765 0.7076895874665317 0.9692961410047456 1.1407252944489767 1.0956403608785723 0.9857775143386444 0.868672941661399 1.0087836239538477 0.8382111876839518 1.0 20.848828165139764 -5.286985161088491 6.084224312614107 0.9944198306514095 0.7238015963680424 0.6027740527745373 0.08554966567995591 0.11180356101808095 15.165808573044234 0.024263889872186535 0.05412527122166351 5.1643401441388505e-06 5.286985161088491 -0.27061823428336707 LSIGES(ph)ITNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LSIGESITNR 10 0 O60296 O60296 TRAK2 Trafficking kinesin-binding protein 2 1 LS(0.017)IGES(0.953)IT(0.03)NR;LS(0.01)IGES(0.987)IT(0.003)NR;LS(0.023)IGES(0.967)IT(0.01)NR;LS(0.006)IGES(0.985)IT(0.009)NR;LS(0.014)IGES(0.981)IT(0.006)NR 84.615 0.0070449 126869200.0 777485.0 807788.0 1158559.0 1251660.0 1392460.0 1326806.0 1252087.0 1225139.0 1272574.0 919565.0 True False 909097.8544712847 887979.8541550895 1186183.440419476 1181533.5481364701 1119617.45885775 1257225.9576515274 1133480.2550351298 1192980.399392072 1291182.987276523 1086274.8552274632 0.8368948706641303 0.8174541184322532 1.0919735780601239 1.0876929926625798 1.0306944448449973 1.157373708506092 1.043456220661374 1.0982307043664976 1.18863377998946 1.0 20.050957757275846 -5.262427231066844 24.948361166547414 1.0897005187503088 0.8271744727037214 0.7926168715706605 0.05320227438358761 31.729995393911548 801371.1044245018 0.013209872635084574 0.03030803731546798 5.464781082580078e-06 5.262427231066844 -0.26252604604658747 LSIGES(ph)ITNR ddPTM_PC-9_Lapatinib_30min_R1 1 LSIGESITNR 10 0 O60296 O60296 TRAK2 Trafficking kinesin-binding protein 2 1 LS(0.016)IGES(0.973)IT(0.011)NR 64.654 0.02882 48133000.0 548080.0 402950.0 627590.0 475460.0 574500.0 601380.0 473280.0 512030.0 628240.0 443400.0 True False 540264.278694438 402016.9940321747 575991.9727674586 510426.9144880634 540709.0395104574 575660.3792852501 497784.1226231752 535820.7830574146 557480.9955395153 520041.0992066368 1.0388876562230434 0.7730485045229751 1.10758933023982 0.9815126444174498 1.0397428978889385 1.1069517008626142 0.9572015046168153 1.0303431476374674 1.0719941104462627 1.0 18.98826611938002 -5.2791945027902605 24.999604233609055 1.0357770659432977 0.9059680437135257 0.32364771603151476 0.0757058454017286 766.5373385500146 1079300.576927514 0.018366707006403537 0.038369112722168794 5.257817374510747e-06 5.2791945027902605 -0.12980902222977198 LSIPSLTCNPDKTDGPVFHS(ph)NTLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSIPSLTCNPDKTDGPVFHSNTLER 25 1 E7ERM3;Q4VCS5-2;Q4VCS5 E7ERM3 AMOT Angiomotin 1 LSIPSLTCNPDKT(0.001)DGPVFHS(0.5)NT(0.5)LER 64.538 0.00038929 2985000.0 5260.9 3559.7 5792.7 7832.0 9702.7 8990.0 8882.1 7893.9 7173.9 8171.5 True False 6151.466462488638 3913.08349076227 5930.819936937089 7393.198431686594 7801.525586414741 8518.548574009486 8040.723187164728 7686.69348927841 7278.804715814591 9652.92826444159 0.6372642885111601 0.4053778691360281 0.6144062997737587 0.7659021417284179 0.8082030004463158 0.8824833605559042 0.832982797228927 0.7963069110949282 0.7540514667064772 1.0 13.236750942249827 -5.74560977652472 2.372097105505017 0.8346687771007448 0.5172151471902037 0.7246986445993968 0.0817236028435677 0.14234194330120478 1.632140014180798 0.023072620390303923 0.0434556316470412 1.7963469605391792e-06 5.74560977652472 -0.31745362991054116 LSKPPFQTNPS(ph)PEMVSK ddPTM_PC-9_AZD4547_30min_R2 3 LSKPPFQTNPSPEMVSK 17 1 H0Y7Y8;Q4LE39-4;Q4LE39-3;Q4LE39-2;Q4LE39 H0Y7Y8 ARID4B AT-rich interactive domain-containing protein 4B 1 LSKPPFQTNPS(0.988)PEMVS(0.012)K;LS(0.001)KPPFQT(0.009)NPS(0.985)PEMVS(0.004)K;LSKPPFQTNPS(0.996)PEMVS(0.004)K 89.816 0.0011756 49813900.0 182597.0 267218.0 253203.0 279977.0 259353.0 238747.0 264300.0 294871.0 270914.0 266824.0 True False 240659.04774645742 353590.99276720174 249845.3627800987 215432.62825152985 223346.31270864885 223818.11234816385 287822.18798305676 249305.46241149039 285233.9609581072 257482.57297490415 0.9346614994790873 1.373261843245853 0.9703389238869 0.8366881912141186 0.8674230264524254 0.8692553820719298 1.1178317221923586 0.9682420815166751 1.1077796748050512 1.0 17.974115265049193 -5.474184926956681 24.97177696711317 0.9589014425525351 1.1584215582598125 0.2384644167460559 0.1329532279864106 476.4395575618952 244332.66655780614 0.0343055666646872 0.07141033879818776 3.3559468422406804e-06 5.474184926956681 0.19952011570727746 LSKPPFQTNPS(ph)PEMVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSKPPFQTNPSPEMVSK 17 1 H0Y7Y8;Q4LE39-4;Q4LE39-3;Q4LE39-2;Q4LE39 H0Y7Y8 ARID4B AT-rich interactive domain-containing protein 4B 1 LSKPPFQTNPS(0.986)PEMVS(0.014)K;LSKPPFQT(0.001)NPS(0.678)PEMVS(0.321)K 64.295 0.010867 26884300.0 104809.0 109533.0 110660.0 115319.0 132154.0 108644.0 120922.0 105408.0 103725.0 91936.0 True False 122551.09362789083 120406.71236162129 113298.55408038729 108858.0502992424 106259.37237542703 102946.51738316886 109467.39276053343 102641.15168900797 105241.78189657922 108603.26903502435 1.1284291413766592 1.1086840518842058 1.0432333675319545 1.0023459815388787 0.9784178074893729 0.94791361528877 1.0079567008727002 0.9451018611226738 0.9690480114612291 1.0 16.72870800437132 -5.456766349518271 1.2887741436393017 0.9716781050139356 1.138569535966424 0.9019067827617149 0.018706962584239855 0.15182651210684944 0.43709895063783216 0.0058692164435945144 0.02423378957717354 3.4932820354625277e-06 5.456766349518271 0.16689143095248848 LSKPPFQTNPS(ph)PEMVSK ddPTM_PC-9_Lapatinib_30min_R1 2 LSKPPFQTNPSPEMVSK 17 1 H0Y7Y8;Q4LE39-4;Q4LE39-3;Q4LE39-2;Q4LE39 H0Y7Y8 ARID4B AT-rich interactive domain-containing protein 4B 1 LSKPPFQTNPS(1)PEMVSK;LSKPPFQTNPS(1)PEMVSK 131.56 1.219e-05 28892000.0 123961.0 161732.0 162808.0 142168.0 164315.0 147613.0 133482.0 154554.0 161145.0 141170.0 True False 122193.29340833645 161357.51949078444 149422.55469705438 152623.508978545 154650.3147557193 141299.9360927095 140393.04482755793 161735.14306711673 142995.15316792176 165571.046402799 0.7380112408727929 0.9745515474863646 0.9024679009006273 0.9218007151277198 0.934042020725581 0.8534096942828817 0.8479323400904989 0.9768322818571169 0.8636483024939342 1.0 17.337090883607537 -14.522878745280218 0.2363103712470497 1.5770123842780301 0.884955600640529 0.19825494077102113 0.06672322692336433 290.35764570509787 2.8943148649791954 80.46997183467802 0.10458544998321334 3.0000000000008234e-15 14.522878745280218 -0.6920567836375011 LSKS(ph)QGGEEEGPLSDK ddPTM_PC-9_AZD4547_30min_R2 1 LSKSQGGEEEGPLSDK 16 1 E9PR76;E9PSH4;Q9H063 E9PR76 MAF1 Repressor of RNA polymerase III transcription MAF1 homolog 1 LS(0.344)KS(0.656)QGGEEEGPLSDK 71.001 0.0088581 14080000.0 20473.0 16621.0 22000.0 40396.0 37641.0 24305.0 20742.0 26542.0 19316.0 27307.0 True False 26982.988135145908 21993.41320862991 21708.265625455348 31083.326311978533 32415.196880954747 22785.20450779322 22587.997817421696 22440.54377448372 20337.004325604423 26350.990241603933 1.0239838384723832 0.8346332721077739 0.8238121386110766 1.1795885477921437 1.2301320209885858 0.8646811485596121 0.8571973049331146 0.8516015363647985 0.7717738171939966 1.0 14.685569557343932 -6.945911413268721 24.999910726332445 0.8582255122063717 1.0104650159142254 0.24374014501852836 0.13054273444921172 149.46057120799347 69080.40709054212 0.05063558464568177 0.04465638332162906 1.132631372107811e-07 6.945911413268721 0.15223950370785377 LSKS(ph)QGGEEEGPLSDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSKSQGGEEEGPLSDK 16 1 E9PR76;E9PSH4;Q9H063 E9PR76 MAF1 Repressor of RNA polymerase III transcription MAF1 homolog 1 LS(0.438)KS(0.562)QGGEEEGPLSDK 81.574 0.0033504 9668200.0 10941.0 9399.0 11873.0 17125.0 26056.0 22779.0 28746.0 32668.0 28784.0 23041.0 True False 12793.095205399883 10332.070604172983 12156.097348603242 16165.541769999101 20950.513844561054 21584.42913986231 26022.9707769826 31810.499614607143 29204.911546022 27218.150907544343 0.47002073171156844 0.37960222350406375 0.44661731026091883 0.5939250548250259 0.7697258316968908 0.7930159992565669 0.9560888564905978 1.168723758004806 1.0729939607296013 1.0 14.732281438781897 -6.612481472612421 0.8100527393781776 1.0974429803917962 0.3972411293267623 0.9424899336815633 0.06419539455011086 0.1369371527459725 0.19898220950520049 0.04193840347738605 0.04711627649818793 2.4407231892358485e-07 6.612481472612421 -0.7002018510650339 down LSKS(ph)QGGEEEGPLSDK ddPTM_PC-9_Lapatinib_30min_R1 4 LSKSQGGEEEGPLSDK 16 1 E9PR76;E9PSH4;Q9H063 E9PR76 MAF1 Repressor of RNA polymerase III transcription MAF1 homolog 1 LSKS(1)QGGEEEGPLSDK;LS(0.131)KS(0.869)QGGEEEGPLSDK;LS(0.016)KS(0.983)QGGEEEGPLS(0.001)DK;LS(0.008)KS(0.992)QGGEEEGPLSDK 163.41 3.1689e-15 21168000.0 70978.6 47624.0 84736.2 80528.1 89288.9 129716.0 99550.7 80484.9 142112.0 104615.7 True False 69966.43214811894 47513.72955400986 77769.5167271911 86450.40510786662 84037.10245073162 124168.34906276483 104704.94814068393 84224.52227857297 126105.85005429696 122698.38435334209 0.5702310793810642 0.38724005865620564 0.6338267381193337 0.7045765562724124 0.6849079789732585 1.011980310231222 0.8533522971187514 0.6864354630459227 1.0277710722835778 1.0 16.90475672669136 -5.997294091154066 0.9618068810253233 0.8948379676671084 0.4655024610227556 0.6689297295752694 0.11598822120115933 0.37531410570824125 0.7032535997941356 0.049995904092964956 0.10997824059500055 1.0062500358436447e-06 5.997294091154066 -0.4293355066443528 LSKS(ph)SATLWNSPSR ddPTM_PC-9_Lapatinib_30min_R1 1 LSKSSATLWNSPSR 14 1 Q3KQU3-4;Q3KQU3;C9JIR3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 LS(0.012)KS(0.926)S(0.031)AT(0.031)LWNSPSR 124.2 0.00018759 7295500.0 39350.0 12844.0 27821.0 19141.0 14869.0 18313.0 13756.0 12942.0 20291.0 12242.0 True False 38788.861784093766 12814.260507133014 25533.66477216565 20548.692992504173 13994.43465357875 17529.79567968803 14468.218371375067 13543.332567093858 18005.613906297414 14358.013388560363 2.7015479603186954 0.8924814429649911 1.7783563840739558 1.4311654709053403 0.974677643407737 1.2209067651138117 1.0076755035555622 0.9432595025913825 1.2540463237513937 1.0 13.809568527544558 -4.754702140019489 24.998298227999875 1.183242113520683 2.7015505390447943 0.7590363982934553 0.2592476356264858 116.77853703807894 433263.8866077566 0.06675106852012302 0.6339611882439707 1.7591296958143136e-05 4.754702140019489 1.5183084255241113 LSLDGQNIYNACCTLR ddPTM_PC-9_Lapatinib_30min_R1 2 LSLDGQNIYNACCTLR 16 0 A6NLN1;P26599;P26599-2;P26599-3;A0A087WU68;K7EK45;A0A0U1RRM4 A6NLN1;A0A0U1RRM4 PTBP1 Polypyrimidine tract-binding protein 1 0 ; 130.19 6.7693e-05 8799100.0 21123.9 27819.9 27365.3 22631.2 28868.0 32319.0 27975.8 27334.0 26887.0 28758.0 False True 20822.669312351165 27755.484730799555 25115.430667112763 24295.573943470066 27170.0409966717 30936.791709268717 29424.250037359314 28604.03742767295 23858.702927338174 33728.78198237371 0.6173561002953757 0.8229020764907629 0.7446290435343266 0.7203217108808336 0.8055446831987727 0.9172223214415494 0.8723780791353837 0.848060195076748 0.7073692414925173 1.0 15.041692600078113 -6.470383250616651 4.260331566288207 0.8602398421936239 0.735669555315677 0.3927425729279438 0.08279593732945532 0.26016773375980407 9.828226800406837 0.02627644070478194 0.029029115634880004 3.385452691984933e-07 6.470383250616651 -0.12457028687794691 LSLEGDHS(ph)TPPSAYGSVK ddPTM_PC-9_AZD4547_30min_R2 1 LSLEGDHSTPPSAYGSVK 18 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 LSLEGDHS(0.908)T(0.092)PPSAYGSVK 187.0 1.0737e-10 63321000.0 104690.0 97787.0 226650.0 310360.0 248890.0 238080.0 169530.0 301710.0 179970.0 239420.0 True False 137979.24231272534 129394.73542099111 223644.47290952073 238811.29701420054 214335.9196541224 223192.81996360485 184617.8415768729 255087.65210607616 189482.84678396318 231037.9786737768 0.5972145493341188 0.5600582906920907 0.9679987428616851 1.0336451971448366 0.9277085996184311 0.9660438567061339 0.7990800587705598 1.1040940263170207 0.8201372253672241 1.0 17.81777049984727 -5.261780519532879 24.992285775396205 0.9530962523081246 0.5786363884093277 0.7496681225797697 0.08637827922818317 12.567202122494287 920775.1876734747 0.02101656626249243 0.0486147568702775 5.472924795583783e-06 5.261780519532879 -0.3744598638987968 LSLEGDHS(ph)TPPSAYGSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LSLEGDHSTPPSAYGSVK 18 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 LS(0.007)LEGDHS(0.781)T(0.212)PPSAYGSVK;LSLEGDHS(0.979)T(0.021)PPSAYGSVK;LSLEGDHS(0.617)T(0.383)PPSAYGSVK;LS(0.103)LEGDHS(0.448)T(0.448)PPSAYGSVK 222.64 5.0017e-29 187490000.0 316300.0 372997.0 572671.0 547707.0 743880.0 604461.0 539951.0 486347.0 464030.0 390350.0 True False 369843.3427902371 410025.67710870446 586325.648506861 517020.7524800516 598122.0539872599 572762.0010672242 488802.9323732873 473580.90657724225 470815.5608914872 461117.36499110033 0.8020590219962225 0.8892002519068395 1.271532353847002 1.12123461776381 1.2971145729868658 1.2421176137625582 1.0600401752007784 1.0270290007108764 1.0210319468245879 1.0 18.814774470949658 -5.111584476960756 5.310172828934862 1.1374507723468295 0.8221231819683413 0.5535201083672054 0.1030991407975742 0.15774023531892015 6.2006255557373935 0.028310574524333033 0.08032556143125007 7.734202220058013e-06 5.111584476960756 -0.3153275903784881 LSLEGDHS(ph)TPPSAYGSVK ddPTM_PC-9_Lapatinib_30min_R1 4 LSLEGDHSTPPSAYGSVK 18 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 LSLEGDHS(0.94)T(0.059)PPSAYGSVK;LSLEGDHS(0.926)T(0.074)PPSAYGSVK;LSLEGDHS(0.85)T(0.15)PPSAYGSVK;LSLEGDHS(0.984)T(0.016)PPSAYGSVK 268.08 2.6073999999999995e-78 138508900.0 641443.0 464175.0 772765.0 499218.0 633625.0 635852.0 467585.0 494174.0 742187.0 427223.0 True False 632295.905193761 463100.23130632757 709231.2446591638 535932.1570624284 596356.4232546799 608658.092203408 491794.2633890237 517135.12811088306 658594.0844844101 501067.9263111346 1.2618965852568687 0.9242264511234526 1.4154393195360335 1.0695798491992183 1.1901708170488179 1.2147217178404393 0.981492204080226 1.0320659155297274 1.3143808451939523 1.0 18.934646667297486 -7.230913738606131 24.612349986921203 1.0846568234922465 1.1739782105650287 0.09508024482795963 0.146485140319805 1540.3953716868468 1241998.0846613399 0.05373459395863743 0.041617963271827624 5.87606053721667e-08 7.230913738606131 0.08932138707278225 LSLEGDHST(ph)PPSAYGSVK ddPTM_PC-9_AZD4547_30min_R2 3 LSLEGDHSTPPSAYGSVK 18 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 LSLEGDHS(0.287)T(0.713)PPSAYGSVK;LSLEGDHS(0.257)T(0.743)PPSAYGSVK;LSLEGDHS(0.214)T(0.785)PPS(0.001)AYGSVK 153.48 4.8367e-05 105046900.0 159611.0 174361.0 371523.0 511446.0 443462.0 404774.0 262148.0 521270.0 323289.0 404891.0 True False 210363.97788495955 230719.78343480668 366596.36227118404 393540.0264619311 381894.95601131726 379463.4177921214 285478.66415203223 440719.6990929513 340377.39653242595 390715.8893292288 0.5384065087450299 0.5905052487906254 0.9382683742413125 1.0072281092472353 0.9774236636931888 0.9712003738664805 0.7306553737605471 1.1279799750390695 0.8711634357045916 1.0 18.57576040154877 -5.246738229758673 4.414306480596227 0.9547283957558282 0.5526152993288889 0.722779781750094 0.09650324947733933 0.09503849380462918 4.813678379614142 0.02441355266830629 0.0641348169525168 5.665806916614806e-06 5.246738229758673 -0.4021130964269394 LSLEGDHSTPPS(ph)AYGSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSLEGDHSTPPSAYGSVK 18 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 LSLEGDHS(0.001)T(0.001)PPS(0.833)AY(0.008)GS(0.158)VK 53.625 0.026576999999999996 6265900.0 17172.0 15423.0 22355.0 31162.0 38152.0 39924.0 18594.0 39961.0 19873.0 15618.0 True False 20078.880437540127 16954.093512943928 22888.027981809624 29416.094168567124 30676.389476423577 37830.31515781475 16832.6417110977 38912.06609217936 20163.60502897774 18449.419767980027 1.0883204290461275 0.9189499575682418 1.2405825369930086 1.5944183903073395 1.662729227380046 2.0504880713631612 0.9123669970538406 2.1091214022737654 1.0929126922448138 1.0 14.171287823964066 -5.562030902474683 3.5253541438068354 1.540778484114283 1.0102389453422043 0.193863829572251 0.38805147045320243 0.308982977125333 7.991632572482816 0.10096604214953883 0.198680129172065 2.741379100574598e-06 5.562030902474683 -0.5305395387720788 LSLEGDHSTPPS(ph)AYGSVK ddPTM_PC-9_Lapatinib_30min_R1 1 LSLEGDHSTPPSAYGSVK 18 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 LSLEGDHS(0.001)T(0.003)PPS(0.734)AY(0.169)GS(0.093)VK 50.924 0.037160000000000006 25120000.0 72190.0 71769.0 91093.0 73702.0 73891.0 87127.0 92002.0 83387.0 93146.0 67514.0 True False 71160.55736197533 71602.82328997414 83603.6851691488 79122.2909426647 69544.87665529548 83400.78131295687 96765.41339075679 87261.46443921 82654.91660913605 79183.70494324958 0.8986767847371578 0.9042620996490552 1.0558193157173812 0.9992244111256362 0.8782725777372732 1.0532568711293522 1.222036951417061 1.1020129015401552 1.043837449490072 1.0 16.2729159510625 -6.96547758023942 8.341445682497383 1.1057566071074882 0.954641673319305 0.4737263199031324 0.07230991541189767 0.21093470792956087 45.162484266434376 0.0262375839398918 0.023021928058869677 1.0827356081850255e-07 6.96547758023942 -0.1511149337881832 LSLEGDHSTPPSAY(ph)GSVK ddPTM_PC-9_AZD4547_30min_R2 4 LSLEGDHSTPPSAYGSVK 18 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 LSLEGDHSTPPS(0.047)AY(0.668)GS(0.286)VK;LSLEGDHSTPPS(0.002)AY(0.712)GS(0.286)VK;LSLEGDHSTPPS(0.006)AY(0.993)GS(0.001)VK;LSLEGDHS(0.001)T(0.026)PPS(0.002)AY(0.931)GS(0.041)VK 210.14 2.0756e-20 128428600.0 26729.7 37045.1 185602.0 354478.0 336370.0 290617.0 162265.0 402894.0 232011.0 304828.0 True False 35229.18858770133 49019.20411858589 183140.79620980733 272758.573730506 289670.83166883874 272444.67304839985 176706.2706510431 340635.98988308525 244274.62780015604 294156.0645024219 0.11976359775989345 0.16664352714095512 0.6225973838737547 0.9272580328809107 0.9847522000229024 0.926190909948609 0.600722854209889 1.1580111069927668 0.8304252649468828 1.0 18.1662222544833 -5.405512562362276 2.296787881154618 0.915658563672495 0.10933316307633074 0.8398565584473003 0.1343049342470449 0.11311127461702192 1.1394109352383683 0.037565480474871335 0.10512985079707345 3.9308587437713555e-06 5.405512562362276 -0.8063254005961642 down LSLEGDHSTPPSAY(ph)GSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LSLEGDHSTPPSAYGSVK 18 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 LSLEGDHSTPPS(0.028)AY(0.774)GS(0.198)VK;LSLEGDHSTPPS(0.009)AY(0.683)GS(0.307)VK;LSLEGDHST(0.002)PPS(0.059)AY(0.58)GS(0.358)VK 86.411 0.0030377 76311000.0 52685.0 79120.0 211875.0 256723.0 403518.0 321205.0 247565.0 227782.0 270010.0 201783.0 True False 61603.52992381799 86974.51071413615 216926.9035404117 242339.6426171956 324451.54457820015 304360.44435091416 224113.85098461297 221802.96385497827 273958.3854412664 238364.66058665057 0.2584423788836928 0.36488005604555246 0.9100631906026783 1.016676054331049 1.361156237588563 1.2768689939265252 0.9402142516975283 0.930519496090941 1.14932467240326 1.0 17.86281083533929 -5.309178204283805 2.1413338518482212 1.1062517577931845 0.24063584642235145 0.8483634760317214 0.13129015877528294 0.13341037669311737 1.1366647700768437 0.04119834528765908 0.1415060346651485 4.907064829865856e-06 5.309178204283805 -0.865615911370833 down LSLEGDHSTPPSAY(ph)GSVK ddPTM_PC-9_Lapatinib_30min_R1 3 LSLEGDHSTPPSAYGSVK 18 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 LSLEGDHSTPPS(0.004)AY(0.687)GS(0.309)VK;LSLEGDHSTPPS(0.002)AY(0.711)GS(0.287)VK;LSLEGDHST(0.017)PPS(0.038)AY(0.939)GS(0.005)VK 150.22 0.00011327 78827400.0 197119.0 122429.0 287522.0 115634.0 257890.0 280426.0 171731.0 206088.0 333734.0 169098.0 True False 194308.04691280247 122145.52317251553 263883.0510270165 124138.11010371626 242721.4172312479 268432.83368493424 180622.39089376337 215663.60084123275 296145.3625451807 198326.36399107776 0.9797388657896433 0.615881422492123 1.3305495331870651 0.6259284323354052 1.2238484705047452 1.353490419947448 0.9107331333008715 1.0874177113988484 1.4932223663340272 1.0 17.597516945604276 -6.301873779773143 24.99106378346269 1.1778889326184128 0.9001945026965613 0.254088348068056 0.243140641398198 745.1367569552283 460540.57599260076 0.07303271705258707 0.08281233946661164 4.990295007336503e-07 6.301873779773143 -0.27769442992185145 LSLEGDHSTPPSAYGS(ph)VK ddPTM_PC-9_AZD4547_30min_R2 1 LSLEGDHSTPPSAYGSVK 18 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 LSLEGDHSTPPS(0.106)AY(0.002)GS(0.892)VK 86.76100000000001 0.00096954 6489700.0 16414.0 21088.0 39279.0 92797.0 92480.0 66566.0 38430.0 86849.0 54405.0 68112.0 True False 21633.310567590725 27904.283601683856 38758.13479555732 71404.08534935807 79640.74832099832 62403.61749704852 41850.19555122528 73428.4826414791 57280.73722999114 65727.41961167924 0.32913676963741106 0.42454555140828143 0.5896798478404027 1.0863667822533858 1.2116822597253885 0.9494305096066771 0.6367235439711196 1.11716667222444 0.8714892136099133 1.0 16.00420772704347 -5.589176153149254 3.6461944895030514 0.9796824202408542 0.39503267754986454 0.7355460878517931 0.14978917532713673 0.12103709168009996 3.2260323703280327 0.044665419343989654 0.08502689183054297 2.5752763934175313e-06 5.589176153149254 -0.5846497426909896 down LSLEGDHSTPPSAYGS(ph)VK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LSLEGDHSTPPSAYGSVK 18 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 LSLEGDHSTPPS(0.007)AY(0.278)GS(0.715)VK;LSLEGDHST(0.002)PPSAYGS(0.997)VK;LSLEGDHSTPPS(0.011)AY(0.301)GS(0.687)VK;LSLEGDHSTPPS(0.014)AYGS(0.985)VK 104.45 0.00027268 57169600.0 48720.7 61403.9 129608.0 148115.0 227539.0 182249.0 117538.0 159749.0 120944.0 96684.0 True False 56968.15223231201 67499.67338776229 132698.34626107692 139816.59674530872 182954.3663523783 172691.5416089716 106403.94973857168 155555.75801805675 122712.57719643154 114212.04384987733 0.4987928620487006 0.5910031123905396 1.1618594833614777 1.2241843507247496 1.6018833056946018 1.5120256654890174 0.9316351074010306 1.3619908441750894 1.0744276440558886 1.0 16.80135526774979 -5.27268385395028 2.8983911977592856 1.2696913198126811 0.5009770331395408 0.6535399886321078 0.20123957151613253 0.1573636795465381 2.62265255669288 0.055975683198991 0.16561539735804603 5.3372327966708495e-06 5.27268385395028 -0.7687142866731403 LSLEGDHSTPPSAYGS(ph)VK ddPTM_PC-9_Lapatinib_30min_R1 4 LSLEGDHSTPPSAYGSVK 18 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 LSLEGDHSTPPS(0.025)AY(0.064)GS(0.91)VK;LSLEGDHSTPPS(0.024)AY(0.001)GS(0.976)VK;LSLEGDHSTPPS(0.022)AY(0.319)GS(0.659)VK;LSLEGDHSTPPS(0.147)AY(0.041)GS(0.813)VK 93.804 0.00056618 33586600.0 164789.0 96196.0 239225.0 131893.0 156365.0 150062.0 109351.0 124744.0 227205.0 138490.0 True False 162439.0786413981 95973.26407226452 219556.8439352045 141592.8512021497 147167.9181254179 143644.1980716073 115012.65972144771 130540.06164036148 201614.78032528237 162427.81197367478 1.000069364153752 0.5908671852811711 1.3517195193812548 0.8717278739499251 0.9060512256932323 0.884357157349926 0.7080847690054964 0.8036804784485957 1.2412577493684318 1.0 17.30943915598167 -8.256033828239882 24.837560758046717 1.1206288781208122 0.888749347325654 0.18155420698605074 0.1962281247086858 634.094613287225 2913591.2455543955 0.13899266592825446 0.049086114121002423 5.545825135120173e-09 8.256033828239882 -0.23187953079515822 LSLEGDHSTPPSAYGSVK ddPTM_PC-9_AZD4547_30min_R2 2 LSLEGDHSTPPSAYGSVK 18 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ; 82.709 0.0021399 33062000.0 87277.0 96262.0 173330.0 297450.0 220755.0 197705.0 154251.0 246507.0 144631.0 195739.0 False True 115029.27052562527 127376.80899399157 171031.5309481898 228877.49805668896 190106.97875867228 185342.47509620493 167979.04017621768 208415.0073173331 152275.89938996139 188886.23718831502 0.6089870402306964 0.674357279228343 0.9054737576125013 1.2117214121243975 1.0064628402181586 0.9812386431914727 0.8893132854817084 1.1033890579838719 0.8061778436411224 1.0 17.52715806095126 -5.302992150855438 3.3787071317727873 1.0019675681140507 0.6282304831258885 0.6468799328563423 0.1042072225990701 0.13794602905479703 3.209931253930959 0.02762186974014566 0.07166622748038591 4.9774608082346395e-06 5.302992150855438 -0.37373708498816227 LSLEGDHSTPPSAYGSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LSLEGDHSTPPSAYGSVK 18 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ;; 93.34200000000001 0.0008777000000000001 25360600.0 39514.1 67787.0 135146.0 146564.0 186757.0 172012.0 144305.0 115939.0 140649.0 92779.0 False True 46203.056690950645 74516.44537132407 138368.39318405927 138352.49424689918 150163.30649634203 162991.3879101803 130635.38572227332 112895.72409752451 142705.7255432338 109599.09826184032 0.4215642046667951 0.679900168460317 1.2624957265021195 1.2623506620133396 1.370114434131482 1.4871599355752165 1.1919385085648766 1.030078950356036 1.3020702524604655 1.0 16.741876402858217 -5.13916742027455 2.918208345542752 1.2553864040006892 0.4473641899271238 0.8005300075753115 0.13956765248086792 0.11605425317066967 1.8242814508449674 0.03882453912976317 0.14473721045333554 7.258260979498757e-06 5.13916742027455 -0.8080222140735654 down LSLEGDHSTPPSAYGSVK ddPTM_PC-9_Lapatinib_30min_R1 2 LSLEGDHSTPPSAYGSVK 18 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ; 100.69 0.00048013 60276000.0 107258.0 104994.0 148930.0 147551.0 171076.0 195800.0 188484.0 135478.0 209039.0 120445.0 False True 105728.48125129184 104750.89284381217 136685.55028642478 158402.3927557068 161013.64602835706 187426.09043209304 198242.77926070493 141772.8024667548 185494.82654174283 141263.75776712547 0.7484473223881398 0.7415270165508051 0.9675910682749365 1.1213236520072933 1.1398086004040007 1.32678114609599 1.4033520160741433 1.0036035052987087 1.3131098129750496 1.0 17.10803185379371 -5.5660275402296016 1.4597482813118037 1.2153267615305692 0.7139883515979438 0.6731092740636737 0.12452031439684466 0.2561876467442566 1.0382490738327064 0.0392059494652213 0.12063406640134981 2.7162670147757764e-06 5.5660275402296016 -0.5013384099326254 LSLFPAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 LSLFPASPR 9 0 Q53GA4 Q53GA4 PHLDA2 Pleckstrin homology-like domain family A member 2 1 LS(0.001)LFPAS(0.999)PR 74.533 0.02729 3463000.0 8933.7 7799.1 10799.0 17225.0 14888.0 12294.0 12215.0 14701.0 11468.0 15135.0 True False 11774.43076749636 10320.006555287013 10655.798204058743 13254.042373597145 12821.058185586311 11525.25423652787 13302.111336409498 12429.298245372805 12074.175067613987 14605.128256735465 0.8061846880438268 0.7066015699333364 0.729592922208307 0.907492364367616 0.8778463263185388 0.7891237950076032 0.9107836030316918 0.8510228754506672 0.8267079107672831 1.0 13.83418740697664 -4.113102419350858 0.03830217227680974 1.491812068363176 1.0836336023685893e-11 0.5221318133274654 0.05808806801017296 419.91034055622333 2.0880273795739783 28.72511726903254 56.232137598316484 7.707216888970647e-05 4.113102419350858 -1.4918120683523395 LSLFPAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 LSLFPASPR 9 0 Q53GA4 Q53GA4 PHLDA2 Pleckstrin homology-like domain family A member 2 1 LSLFPAS(1)PR 77.744 0.022612 2641800.0 14089.0 12086.0 13144.0 10954.0 11376.0 9821.9 7701.1 7709.8 10327.0 9009.6 True False 13888.08827639383 12058.015609561626 12063.351057307254 11759.593701472799 10706.886046076534 9401.840232967179 8099.825276228304 8068.025454008672 9163.864511868982 10566.89735546262 1.3143014272977962 1.141112211459891 1.1416171323998934 1.112871007059949 1.0132478518438097 0.8897446352222624 0.7665282441719802 0.763518862974273 0.8672237652740771 1.0 13.367264215402662 -6.398577613756095 1.205492011424313 0.8262650754166888 1.2059648459152588 0.7961206764911605 0.07714117898873865 0.1919881652934558 0.5785447401375079 0.03303265855647395 0.04211274181695687 3.994131748913942e-07 6.398577613756095 0.37969977049856996 LSLGGIS(ph)PAGQETVDANLQK ddPTM_PC-9_AZD4547_30min_R2 1 LSLGGISPAGQETVDANLQK 20 0 Q5HYI7-5;Q5HYI7 Q5HYI7-5 MTX3 Metaxin-3 1 LSLGGIS(0.999)PAGQET(0.001)VDANLQK 127.59 2.3482e-05 3240100.0 26417.0 27683.0 41930.0 44586.0 43788.0 36460.0 34672.0 43752.0 32462.0 41391.0 True False 34817.05649226538 36630.988379429735 41373.98080342472 34307.386546833215 37708.7920358983 34180.15043629462 37757.74083143596 36991.133720940816 34177.87504751353 39941.913688439876 0.8716922469927185 0.9171064928226411 1.035853743167026 0.8589319684189938 0.9440907696621484 0.8557464397652824 0.9453162691692446 0.9261232200711234 0.8556894723200358 1.0 15.28561583608401 -10.676686704804359 4.643696628533185 1.0000099823790825 0.9151417876040815 0.19350850366426964 0.053436095040775455 5.370062618539832e-06 9.785448550172435e-07 0.050311228105417834 0.01220082995827455 2.105296629606651e-11 10.676686704804359 -0.08486819477500096 LSLGGIS(ph)PAGQETVDANLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSLGGISPAGQETVDANLQK 20 0 Q5HYI7-5;Q5HYI7 Q5HYI7-5 MTX3 Metaxin-3 1 LSLGGIS(0.969)PAGQET(0.031)VDANLQK 124.51 1.0401e-05 3577300.0 18843.0 18765.0 13565.0 20542.0 24083.0 20633.0 20731.0 17059.0 22440.0 17399.0 True False 22032.747733785745 20627.865186435374 13888.441045548972 19391.098338062566 19364.109031262044 19550.9691576794 18767.20960055751 16611.21932550456 22768.142547690848 20553.300969591786 1.0719809808839356 1.003627846298456 0.6757280042800256 0.9434542104332205 0.9421410731011467 0.9512325629155474 0.9130995370681935 0.8082020182587965 1.1077608692334082 1.0 14.32708249657149 -8.274206055117727 24.947821852539096 1.0538804405055866 0.9119227291460961 0.2224548438969084 0.10480202917812148 1320.9021844603117 2581195.280288743 0.09990329428256782 0.026506954827294867 5.318558553612423e-09 8.274206055117727 -0.14195771135949053 LSLGGIS(ph)PAGQETVDANLQK ddPTM_PC-9_Lapatinib_30min_R1 1 LSLGGISPAGQETVDANLQK 20 0 Q5HYI7-5;Q5HYI7 Q5HYI7-5 MTX3 Metaxin-3 1 LS(0.004)LGGIS(0.996)PAGQETVDANLQK 178.77 3.9035e-37 0.0 9683.5 6977.1 8175.2 8094.9 7314.5 5709.2 4888.4 9007.4 7881.8 5060.9 True False 9545.411514263587 6960.944953621751 7503.066613184596 8690.225949794794 6884.275490860301 5465.030824795225 5141.4974328751 9425.91668713036 6994.068684966486 5935.669821774639 1.6081439501986505 1.172731159689165 1.2640640127353544 1.4640682872748811 1.1598144266053616 0.9207100443402523 0.8662034087566383 1.5880123002381241 1.1783116135114484 1.0 12.535195127339007 -1.52287874528042 0.731296705074032 1.1621063932440794 61.386515545960535 0.25394907570239433 0.21477370322421885 567.5396510737439 2.6499267841167096 0.0868968249732946 56162.9275687394 0.029999999999994306 1.52287874528042 60.224409152716454 LSLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 LSLSPK 6 0 Q5FBB7-6;Q5FBB7;Q5FBB7-5;Q5FBB7-4;Q5FBB7-3;Q5FBB7-2 Q5FBB7-6 SGOL1 Shugoshin-like 1 1 LSLS(1)PK 93.195 0.034816 12252000.0 181940.0 170240.0 133970.0 150080.0 150290.0 143220.0 136520.0 126310.0 131910.0 129840.0 True False 179345.50223629 169845.81973951426 122955.50373915477 161117.38385220314 141450.23768150862 137094.81446212638 143588.3376025096 132178.82371732531 117052.90672611968 152282.6709990752 1.1777144507622876 1.1153325498246989 0.8074162538159149 1.0580152212669136 0.9288662771246482 0.9002653654726016 0.9429066134739756 0.8679833552310625 0.7686554613087297 1.0 17.21639225417333 -5.124892984160393 5.376179109716182 0.9119341596173868 1.162702391656045 0.586172987946159 0.0803005492839224 0.14530855928163586 5.62994114628939 0.020444676028784796 0.0575932413570266 7.500790158404316e-06 5.124892984160393 0.2507682320386583 LSLS(ph)PLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LSLSPLR 7 0 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 LS(0.007)LS(0.993)PLR;LS(0.024)LS(0.976)PLR;LS(0.004)LS(0.996)PLR 126.24 0.0045604999999999995 263711000.0 133686.0 149837.0 160707.0 145093.0 147776.0 122147.0 147713.0 100283.0 117142.0 94913.0 True False 156316.39938114284 164711.82712176477 164538.86436469128 136963.909607853 118820.35361889229 115741.39629249572 133720.55529049013 97650.6775086214 118854.980139109 112119.97556910542 1.3941886678774458 1.4690676330039356 1.4675249751840818 1.2215834770980214 1.0597607876364286 1.0322995140251188 1.19265594388282 0.8709480805089381 1.0600696221687316 1.0 16.77468380955726 -5.999671043514739 2.3415757943774436 1.034867689557992 1.4498469979825033 0.8476739714813858 0.0773191687287331 0.10759263823027497 1.184424698393936 0.024283227566994848 0.03734551270892523 1.0007577372371268e-06 5.999671043514739 0.41497930842451125 LSLS(ph)PLR ddPTM_PC-9_Lapatinib_30min_R1 2 LSLSPLR 7 0 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 LS(0.023)LS(0.977)PLR;LS(0.012)LS(0.988)PLR 114.89 0.0084641 203632000.0 79393.0 106610.0 121890.0 102544.0 112780.0 112033.0 95815.0 100743.0 114254.0 91735.0 True False 78260.84126110683 106363.1510950988 111868.67470900668 110085.42783675616 106146.5021340111 107241.60975167873 100775.83187360429 105423.88756040292 101385.51137204217 107591.27252079599 0.7273902374003434 0.9885853062527928 1.039756033068425 1.0231817624006454 0.9865716767453825 0.9967500824098007 0.936654335546832 0.9798553831587581 0.9423209615114987 1.0 16.715201530011377 -4.761447067667924 12.507087138326327 0.9888856061781846 0.7271188163190037 0.8726476199944585 0.02988758637976177 0.020472396248489556 218.21302216351063 0.008122249826702779 0.04539357145408567 1.7320201185743893e-05 4.761447067667924 -0.2617667898591809 LSLTSDPEEGDPLALGPES(ph)PGEPQPPQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSLTSDPEEGDPLALGPESPGEPQPPQLK 29 0 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 1 LSLTSDPEEGDPLALGPES(1)PGEPQPPQLK 88.709 1.0627999999999999e-05 0.0 6039.6 8891.3 6965.2 8795.8 9511.3 6491.0 7193.8 6746.8 7324.1 5747.4 True False 7061.984992462578 9773.96950344539 7131.276783668101 8302.999842368352 7647.6290424383415 6150.600533247562 6512.351185398227 6569.703648825494 7431.201106664106 6789.358123606635 1.0401550284861272 1.439601406421801 1.050360969893842 1.2229432725751757 1.1264141474357485 0.9059178233450216 0.9591998340395018 0.9676472398742083 1.0945366220741517 1.0 12.729059470963842 -6.586976032212068 5.1164221849155735 0.9826655107173928 1.194317690367662 0.4269013595768685 0.11190098674635744 0.18289475620821463 9.39712516032231 0.0357649971561253 0.03597340563850528 2.5883557570556383e-07 6.586976032212068 0.21165217965026917 LSLVIRS(ph)PSLLQSGAK ddPTM_PC-9_AZD4547_30min_R2 2 LSLVIRSPSLLQSGAK 16 1 Q9BQG0;Q9BQG0-2;I3L1L3;I3L2H8 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 LS(0.197)LVIRS(0.699)PS(0.103)LLQS(0.001)GAK;LS(0.027)LVIRS(0.911)PS(0.06)LLQS(0.002)GAK 66.702 0.01239 20526700.0 28585.0 20484.1 34991.0 61296.0 34890.0 23723.0 26180.7 33691.0 20914.1 31248.0 True False 37674.43539506401 27105.184736592 34526.99647728674 47165.15421375965 30046.125745238234 22239.597059797517 28510.731581263724 28484.83009216076 22019.57662901863 30154.017031150946 1.2494002161020208 0.8988913387092236 1.1450214557356733 1.5641416586398806 0.9964219929370852 0.7375334781041827 0.9455035974746049 0.9446446243873307 0.7302369235339708 1.0 14.880062586148556 -6.514332783151624 24.7003518316143 0.872103273229187 1.1985525353566064 0.4699429745186188 0.17150679923699333 337.6961634109163 976045.1298192835 0.05695695208927124 0.059751854047698866 3.0596180676197984e-07 6.514332783151624 0.3264492621274194 LSLVIRS(ph)PSLLQSGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSLVIRSPSLLQSGAK 16 1 Q9BQG0;Q9BQG0-2;I3L1L3;I3L2H8 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 LS(0.008)LVIRS(0.959)PS(0.032)LLQS(0.001)GAK;LS(0.012)LVIRS(0.961)PS(0.025)LLQS(0.003)GAK 64.26 0.014396 14861200.0 32114.0 16473.4 25301.0 34518.0 34270.0 32782.0 29168.0 30730.0 28106.0 20724.5 True False 37550.265919587946 18108.770283092166 25904.271794576824 32584.06836886591 27555.039509253394 31062.854210587233 26404.995881967174 29923.370061126407 28516.99707867197 24481.687794948266 1.533810341594845 0.7396863498450815 1.058108085175488 1.3309567805038975 1.1255367579248072 1.2688199633440704 1.0785610903597822 1.2222756172595672 1.1648297011840982 1.0 14.579415402018947 -4.694849234552198 23.902887539436612 1.1265807179290568 1.533841891711845 0.39360923781152146 0.15662933904900497 37137.91616899806 13327084.51139465 0.03930209815369039 231.1169807692882 2.019067161749099e-05 4.694849234552198 0.40726117378278825 LSLVIRS(ph)PSLLQSGAK ddPTM_PC-9_Lapatinib_30min_R1 1 LSLVIRSPSLLQSGAK 16 1 Q9BQG0;Q9BQG0-2;I3L1L3;I3L2H8 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 LS(0.193)LVIRS(0.754)PS(0.053)LLQSGAK 53.536 0.035222 5536300.0 15430.0 7576.7 12730.0 8897.4 9273.0 9620.2 7042.4 7984.2 11976.0 6062.1 True False 15209.965370484557 7559.15661666106 11683.38853922105 9551.744476856316 8727.580371419444 9208.766471781517 7407.021013272158 8355.175079755118 10627.136767129163 7109.925907759496 2.139257928677568 1.0631835992005614 1.6432503925913287 1.343437976819409 1.2275205796300217 1.2951986548455348 1.0417859636467413 1.1751423556519212 1.494690226733744 1.0 12.795618810320434 -4.7531111706353215 24.999815810071475 1.2680926563132213 2.139259543161079 0.6530768808329224 0.19335553875146677 195.88464673834903 587965.9041260439 0.04741220257219163 0.5268946124588928 1.7655858084493258e-05 4.7531111706353215 0.8711668868478575 LSMEDS(ph)KSPPPK ddPTM_PC-9_AZD4547_30min_R2 1 LSMEDSKSPPPK 12 1 Q9NQG5 Q9NQG5 RPRD1B Regulation of nuclear pre-mRNA domain-containing protein 1B 1 LS(0.038)MEDS(0.481)KS(0.481)PPPK 55.98 0.037021 78003000.0 217590.0 228640.0 191710.0 182240.0 218510.0 219370.0 223300.0 238620.0 240210.0 249040.0 True False 286779.0938468417 302543.40870110976 189167.80013891144 140227.38357993285 188173.65825715076 205652.75922133765 243173.26741058024 201746.76194210278 252907.0102015656 240321.18540187684 1.1933159091541417 1.2589127679075895 0.7871457517262817 0.5834998830645654 0.7830090299466423 0.855741281724435 1.0118677926955713 0.8394880443217354 1.052370850196341 1.0 17.87460430861831 -5.258610445368595 24.999996973809374 0.85046335070923 1.2261143751784438 0.5485385412932909 0.1308845852509642 181.20991105179175 1601375.1670769062 0.03622975817659774 0.0874946617963697 5.513019830231724e-06 5.258610445368595 0.37565102446921383 LSMEDS(ph)KSPPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSMEDSKSPPPK 12 1 Q9NQG5 Q9NQG5 RPRD1B Regulation of nuclear pre-mRNA domain-containing protein 1B 1 LS(0.001)MEDS(0.905)KS(0.094)PPPK 82.54299999999999 0.026044 3869400.0 28102.0 31334.0 22665.0 30178.0 31170.0 23495.0 27960.0 27136.0 21229.0 24900.0 True False 32859.11356019992 34444.632440808185 23205.419557491165 28487.224498396077 25062.4622557172 22262.880839416346 25311.42638712982 26423.708752968614 21539.433963677777 29414.17289170844 1.1171183932716522 1.1710216217066496 0.788919669539052 0.9684863349132737 0.8520539519498798 0.7568759768081743 0.8605180393926649 0.8983325436431766 0.7322807968450313 1.0 14.844223848681603 -5.256860045775855 24.98786601726404 0.8538810259130296 1.1440700384264524 0.6647192333104948 0.08147258654260811 205.78866912407116 1122908.8194924535 0.02004354450412248 0.04941572604845296 5.535284586264474e-06 5.256860045775855 0.2901890125134228 LSMEDS(ph)KSPPPKATEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSMEDSKSPPPKATEEK 17 2 Q9NQG5 Q9NQG5 RPRD1B Regulation of nuclear pre-mRNA domain-containing protein 1B 1 LS(0.211)MEDS(0.719)KS(0.071)PPPKATEEK 70.615 0.013058000000000002 8753500.0 30215.0 14835.0 20030.0 35161.0 35676.0 33259.0 33862.0 42433.0 33304.0 26839.0 True False 35329.802726547576 16307.720758900548 20507.591164198024 33191.043163500064 28685.54390230885 31514.839490876708 30654.34622035014 41319.17871147986 33791.0079950221 31704.698242592905 1.1143396620972916 0.514362907166621 0.6468312994901052 1.046880904197043 0.9047726517633893 0.9940116524603556 0.9668707768733249 1.3032509691566978 1.0658044349283977 1.0 14.952409025246858 -6.487128797867004 0.934008482904362 1.1106936712002533 0.7575127357538001 0.3048046550106951 0.17935502854226665 0.6282609965593308 1.1919058172454924 0.09587491823870495 0.1185737117788264 3.2574008257511667e-07 6.487128797867004 -0.35318093544645324 LSMEDSKS(ph)PPPK ddPTM_PC-9_AZD4547_30min_R2 1 LSMEDSKSPPPK 12 1 Q9NQG5 Q9NQG5 RPRD1B Regulation of nuclear pre-mRNA domain-containing protein 1B 1 LS(0.03)MEDS(0.019)KS(0.952)PPPK 53.395 0.042652999999999996 84149000.0 133840.0 145910.0 133730.0 112940.0 145610.0 160790.0 151950.0 173140.0 165490.0 136440.0 True False 176398.33595505895 193072.5540744354 131956.65282237026 86903.42790560576 125394.56491155426 150735.77588183823 165473.2556338453 146385.19136139337 174237.46354546887 131663.2771291037 1.339768687225443 1.4664115787207412 1.0022282271842504 0.6600430264271165 0.9523883017783115 1.1448581500370283 1.2567912575318092 1.1118148853142549 1.3233565755363863 1.0 17.00649348676253 -5.262702093741271 24.91590776335274 1.0528691690793819 1.4030901521558017 0.38693856559255935 0.17449123120160134 112.88399158488565 2227482.418456031 0.05075461610462155 0.11592937629004738 5.461323545857718e-06 5.262702093741271 0.3502209830764198 LSMEDSKS(ph)PPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSMEDSKSPPPK 12 1 Q9NQG5 Q9NQG5 RPRD1B Regulation of nuclear pre-mRNA domain-containing protein 1B 1 LS(0.019)MEDS(0.09)KS(0.891)PPPK 78.763 0.03499 23885000.0 39802.0 40659.0 33566.0 39370.0 41877.0 32549.0 43165.0 32176.0 28070.0 26542.0 True False 46539.69247466645 44695.356814030165 34366.340739763895 37164.22653926217 33671.50246655984 30842.073140760254 39076.09871246272 31331.414093290034 28480.470646777285 31353.85449364362 1.4843371963756948 1.4255139451224816 1.0960802521658382 1.1853160365592845 1.0739190766285553 0.9836772428414784 1.2462932976991596 0.9992842857531875 0.9083562804870178 1.0 14.936355191541294 -1.5228789831495726 0.4062849380734825 1.0061437848593693 10.009605190094556 0.7437799124724017 0.09295427702854935 37.44273492847449 0.49159563217106184 0.06660903395081862 271.17198733082006 0.02999998356857986 1.5228789831495726 9.003461405235186 LSMEDSKS(ph)PPPKATEEK ddPTM_PC-9_Lapatinib_30min_R1 1 LSMEDSKSPPPKATEEK 17 2 Q9NQG5 Q9NQG5 RPRD1B Regulation of nuclear pre-mRNA domain-containing protein 1B 1 LS(0.007)MEDS(0.397)KS(0.596)PPPKATEEK 85.054 0.0092791 7674400.0 50261.0 28465.0 30797.0 32892.0 29275.0 27012.0 24486.0 26754.0 29446.0 20215.0 True False 49544.26892326144 28399.091041384385 28264.989539857856 35310.987404495434 27553.102056864467 25856.759728047473 25753.765269081847 27997.088510278834 26129.481399873544 23709.13581520566 2.089669961377784 1.1978121540461573 1.1921560431456273 1.489340973020578 1.162130170902033 1.0905821253706114 1.0862380421544036 1.1808565579316952 1.102084934834091 1.0 14.53315545789705 -4.761327782521419 6.814670795765601 1.1769083363118162 2.111325818638628 0.8356588224951904 0.12273927979981185 0.04545659736183312 11.30348079071789 0.03196120401014759 0.19667137932273598 1.7324959078330634e-05 4.761327782521419 0.9344174823268117 LSMPQSAAVS(ph)TTPPHNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSMPQSAAVSTTPPHNR 17 0 A2A2F0;Q86X10-4;Q86X10-2;Q86X10-3;Q86X10 A2A2F0 RALGAPB Ral GTPase-activating protein subunit beta 1 LSMPQSAAVS(0.462)T(0.317)T(0.22)PPHNR 59.618 0.026525 8189600.0 20455.0 28411.0 31469.0 28918.0 34892.0 27756.0 30047.0 25802.0 25800.0 23504.0 True False 23917.627495334473 31231.456318242217 32219.34030684711 27297.818213420953 28055.163074317774 26300.426498354554 27200.730638558285 25124.724839478793 26177.27619119537 27765.089142438384 0.8614280823171159 1.1248462469549778 1.1604263231988148 0.9831705590203484 1.0104474338400742 0.9472480482029095 0.9796738090418198 0.9049034458555422 0.942812611077986 1.0 14.760984407395078 -6.404059464818607 1.790147316787874 0.9504359834548409 1.0520681736759905 0.17114071280891152 0.0792137072001018 0.540780383834107 3.4456885286520826 0.029483798671814665 0.03507438001029926 3.9440329557251743e-07 6.404059464818607 0.10163219022114955 LSMPQSAAVST(ph)TPPHNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSMPQSAAVSTTPPHNR 17 0 A2A2F0;Q86X10-4;Q86X10-2;Q86X10-3;Q86X10 A2A2F0 RALGAPB Ral GTPase-activating protein subunit beta 1 LSMPQSAAVS(0.069)T(0.597)T(0.335)PPHNR 123.17 4.8253999999999996e-05 8717100.0 11217.0 12788.0 16032.0 14781.0 17049.0 13647.0 18890.0 12451.0 11504.0 9361.3 True False 13115.816554151403 14057.508127052255 16414.263681698572 13952.868490648556 13708.370837270533 12931.327295829535 17100.602448243288 12124.174442924977 11672.224236570206 11058.429585989972 1.186046938415917 1.271202933268377 1.4843213997124833 1.2617405014113012 1.2396308834518237 1.1693638048039257 1.546386158655674 1.0963739786601532 1.055504684983287 1.0 13.432858901707204 -7.97584031640458 24.797007205818847 1.0438145524162343 1.3051821312191825 0.5178021652670529 0.11502398606568016 158.5387444482363 162720.78469718728 0.06272339645224043 0.030129086379137138 1.0572061566752728e-08 7.97584031640458 0.26136757880294814 LSMPQSAAVSTT(ph)PPHNR ddPTM_PC-9_AZD4547_30min_R2 2 LSMPQSAAVSTTPPHNR 17 0 A2A2F0;Q86X10-4;Q86X10-2;Q86X10-3;Q86X10 A2A2F0 RALGAPB Ral GTPase-activating protein subunit beta 1 LSMPQSAAVS(0.042)T(0.469)T(0.489)PPHNR;LSMPQSAAVS(0.002)T(0.092)T(0.905)PPHNR 138.04 6.5663e-05 17236700.0 12629.1 14139.0 21350.0 32107.0 30123.0 28217.0 24960.0 38623.0 24701.0 27914.0 True False 16644.891098401364 18709.1552467853 21066.885050157824 24705.227198205142 25940.94141082864 26452.586529372616 27181.39164607295 32654.702818245947 26006.644431909048 26936.739356360344 0.6179252387676665 0.6945590184198618 0.7820874223658952 0.9171573022022692 0.9630319790247154 0.9820263016773257 1.0090824760367605 1.2122737791771916 0.9654711391699426 1.0 14.71728760528991 -5.535577624230133 0.688968564198692 1.0619663543866222 0.5330273068227384 0.8468445601932311 0.06410382227724344 0.4883702239489889 0.3350222837604778 0.0323008298538666 0.175207691911246 2.91354933092436e-06 5.535577624230133 -0.5289390475638839 LSMPQSAAVSTT(ph)PPHNR ddPTM_PC-9_Lapatinib_30min_R1 1 LSMPQSAAVSTTPPHNR 17 0 A2A2F0;Q86X10-4;Q86X10-2;Q86X10-3;Q86X10 A2A2F0 RALGAPB Ral GTPase-activating protein subunit beta 1 LSMPQSAAVS(0.002)T(0.09)T(0.909)PPHNR 125.37 3.8573000000000005e-05 7585200.0 15642.0 17132.0 18357.0 15009.0 16339.0 14688.0 14979.0 14821.0 16869.0 10884.0 True False 15418.942211608513 17092.33190658694 16847.758320069177 16112.811928556257 15377.972143709942 14059.828479400308 15754.539327190112 15509.637766720603 14969.035581554936 12765.284897981614 1.207880774681847 1.3389698736210345 1.3198105999759602 1.2622367661456533 1.2046712836108682 1.1014112565261573 1.2341706004290705 1.214985634137544 1.1726362318730363 1.0 13.639938115987672 -14.522878741985533 0.09094249521760418 0.23415997382688053 1.4206326052754514 0.6543920571209402 0.055511640450444794 137.20061760003657 0.8620885622208229 20.194058834290875 1.3697109306894097 3.000000022759704e-15 14.522878741985533 1.186472631448571 LSMS(ph)EVKDDNS(ph)ATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSMSEVKDDNSATK 14 1 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;Q8TDM6-5 Q8TDM6-4 DLG5 Disks large homolog 5 2 LS(0.087)MS(0.913)EVKDDNS(0.852)AT(0.148)K 88.78 0.037549 0.0 8041.2 11938.0 8605.8 9499.7 10593.0 7009.2 6935.6 5762.8 5855.5 5612.9 True False 9402.416339060554 13123.125744506551 8810.994909678242 8967.462607442945 8517.377692486765 6641.625213008602 6278.609758604349 5611.53260619132 5941.125609982344 6630.474338308046 1.4180608896617566 1.9792137145734419 1.328863435723155 1.3524617018171354 1.2845804474767362 1.0016817612333 0.9469322160451216 0.8463244588355141 0.8960332710522776 1.0 12.694896367827418 -6.217158473010986 0.8172143197713083 0.8883051133523896 1.6975894245156977 0.7583331886683218 0.1602250002179839 0.30273514833905646 0.4311534413683384 0.08220769965565579 0.14749110982150904 6.065149733510465e-07 6.217158473010986 0.8092843111633081 LSNIFVIGK ddPTM_PC-9_Lapatinib_30min_R1 2 LSNIFVIGK 9 0 P62701 P62701 RPS4X 40S ribosomal protein S4, X isoform 0 ; 111.61 0.010245 8265800.0 79299.0 76895.0 79557.0 66994.0 70838.0 74806.0 78507.0 68847.0 71907.0 68213.0 False True 78168.18171834439 76716.95435191483 73016.13055890086 71920.96224543265 66671.44811286649 71606.7217613031 82571.7083222988 72045.88295833021 63808.07644572125 80003.52616189064 0.9770592056176081 0.9589196630742839 0.9126614045879617 0.8989724040400098 0.8333563695424362 0.8950445711155751 1.0321008620946448 0.9005338441275977 0.7975658012448453 1.0 16.28777596785148 -5.206035172475117 2.8704475409384207 0.9054724346723213 0.9744506387923226 0.11980381527455852 0.06481526427504515 0.6011948532741397 9.563415140918849 0.017897845103363414 0.06007229348173659 6.2224988859285194e-06 5.206035172475117 0.06897820412000133 LSNRPAFMPSEGK ddPTM_PC-9_Lapatinib_30min_R1 1 LSNRPAFMPSEGK 13 1 O43707;O43707-2;K7EJH8 O43707 ACTN4 Alpha-actinin-4 0 73.38600000000001 0.027741000000000002 13113000.0 59226.0 52398.0 51668.0 49871.0 59931.0 49205.0 49352.0 50347.0 52868.0 57149.0 False True 58381.426379281795 52276.675650323494 47420.0564842477 53538.67970477907 56405.97640887945 47100.61685245729 51907.205078809435 52686.30542075983 46913.44911527929 67027.12850374424 0.8710118974591089 0.7799330930222266 0.7074755780653611 0.7987613508131758 0.8415395030047949 0.7027097520644373 0.7744208388087193 0.7860444956674026 0.6999173344067489 1.0 16.032457508498624 -10.839352988183519 6.067113522134479 1.0000161926020545 0.7728331220249244 0.6079342664386842 0.05455730039004226 1.180676052411226e-05 1.330064076613863e-06 0.05219339088381556 0.01265785513131779 1.4475947914507911e-11 10.839352988183519 -0.22718307057713016 LSPAT(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 1 LSPATPSR 8 0 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 LS(0.001)PAT(0.922)PS(0.078)R 82.831 0.03891 12384000.0 41496.0 58021.0 65137.0 53552.0 68616.0 65873.0 56871.0 63371.0 61185.0 54809.0 True False 40904.25943056557 57886.655939299635 59781.68729609121 57490.39272423512 64580.14178424635 63055.765347463006 59815.50210805985 66315.44800720939 54293.70099338661 64282.662621598174 0.6363186862894856 0.9005018395092185 0.929981504468754 0.894337452427166 1.0046276733183765 0.9809140252736989 0.9305075376259009 1.0316226071340147 0.8446087759772508 1.0 15.972142066985278 -4.317690981978892 1.4575596514306801 0.9566012017949181 2.846372500405249e-15 0.7581137914605734 0.05318081443161675 1.806074738033237 1.4100309349738847 0.014255735441511387 3.5036298563251753 4.8118160676947634e-05 4.317690981978892 -0.9566012017949153 LSPAT(ph)PTSEGPK ddPTM_PC-9_AZD4547_30min_R2 2 LSPATPTSEGPK 12 0 Q8N1G0;Q8N1G0-2;F8WCX2 Q8N1G0 ZNF687 Zinc finger protein 687 1 LS(0.001)PAT(0.49)PT(0.401)S(0.108)EGPK;LS(0.004)PAT(0.476)PT(0.476)S(0.043)EGPK 139.78 0.0001796 24991100.0 145699.0 170979.0 183309.0 244006.0 216860.0 229860.0 169290.0 227971.0 170671.0 184636.0 True False 192028.25127253582 226244.61807342104 180878.2028880271 187754.18655512022 186752.73227607764 215486.8178630469 184356.48204181448 192743.32020242768 179692.32062824786 178171.94983882413 1.0777692641644558 1.269810530097941 1.0151889960886158 1.0537808376961932 1.04816011973274 1.2094317767638403 1.0347110317229222 1.0817826283923195 1.0085331658030294 1.0 17.442910701230737 -1.5228787499572365 0.07465748604769842 0.9043797836941397 1.5288537528642037 0.19522519252461423 0.07625232504942178 372.6880604004557 2.0505832854203256 2.8005453532828146 24.21791453558044 0.02999999967693127 1.5228787499572365 0.6244739691700639 LSPAT(ph)PTSEGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LSPATPTSEGPK 12 0 Q8N1G0;Q8N1G0-2;F8WCX2 Q8N1G0 ZNF687 Zinc finger protein 687 1 LSPAT(0.703)PT(0.281)S(0.016)EGPK;LS(0.002)PAT(0.64)PT(0.296)S(0.061)EGPK;LS(0.043)PAT(0.377)PT(0.335)S(0.244)EGPK 131.06 0.00031217 26930700.0 216602.0 225598.0 205683.0 252643.0 322364.0 288852.0 350844.0 267526.0 261389.0 237341.0 True False 253268.44051549394 247993.87851475814 210587.2627771215 238488.23178965712 259199.0883093366 273704.0926251158 317609.5164294056 260503.72596722742 265211.3196255953 280369.0445096779 0.9033395286502519 0.8845266029581157 0.7511073954166589 0.850622550741064 0.9244925336270119 0.9762279323802738 1.132826617806026 0.9291458207264219 0.9459365248021901 1.0 18.09696754490625 -6.53196992492448 2.4930273872329027 1.0012640769057266 0.8436660366086713 0.5551461887623379 0.06311358630705137 0.22885012929970452 2.867136223257684 0.023707984738684153 0.025255767424564046 2.9378530924794837e-07 6.53196992492448 -0.15759804029705526 LSPAT(ph)PTSEGPK ddPTM_PC-9_Lapatinib_30min_R1 3 LSPATPTSEGPK 12 0 Q8N1G0;Q8N1G0-2;F8WCX2 Q8N1G0 ZNF687 Zinc finger protein 687 1 LS(0.001)PAT(0.988)PT(0.009)S(0.002)EGPK;LSPAT(0.613)PT(0.309)S(0.077)EGPK;LSPAT(0.65)PT(0.291)S(0.059)EGPK 139.78 0.0001796 40608300.0 252202.0 229262.0 226619.0 198850.0 303840.0 289783.0 318786.0 284375.0 298748.0 267609.0 True False 248605.55323181767 228731.1579248151 207987.26059463742 213474.09234415393 285968.7285724236 277389.6566071664 335291.1792481225 297588.1006619773 265099.85428409354 313864.8590834214 0.7920783293734116 0.7287568241719637 0.6626650119482059 0.6801465221929007 0.9111205676466528 0.8837869184120407 1.0682660691205517 0.9481408703447176 0.8446305682587845 1.0 18.25978398547192 -6.351211307841133 4.031709494386841 0.9481896642730911 0.7129160068152056 0.7438598081701339 0.0653321593378858 0.12301682838412384 3.6512356009510945 0.0217934058413271 0.025114275074852557 4.4543946518287453e-07 6.351211307841133 -0.23527365745788553 LSPATPS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 LSPATPSR 8 0 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 LSPAT(0.416)PS(0.584)R 84.31 0.014072 13528000.0 60110.0 59051.0 78532.0 107050.0 98754.0 82387.0 70519.0 109020.0 96347.0 86852.0 True False 79223.72963432902 78138.08094475689 77490.61436810267 82371.27640601303 85043.71171812118 77235.32786601767 76795.05438659544 92173.46403037524 101439.7057237011 83811.33791569117 0.9452626769187602 0.9323091945311598 0.9245839082780574 0.9828178198142267 1.014704141862879 0.9215379420826268 0.9162847926833758 1.099773208764378 1.210333926726512 1.0 16.354857803048084 -7.809983030040535 6.694890713474758 1.1188216936565265 0.9496064869289588 0.6175779140050824 0.05560894021643054 0.12419945709032795 12.742475892712315 0.029688211696018974 0.014291162920126221 1.5488771397568652e-08 7.809983030040535 -0.16921520672756774 LSPATPT(ph)SEGPK ddPTM_PC-9_AZD4547_30min_R2 1 LSPATPTSEGPK 12 0 Q8N1G0;Q8N1G0-2;F8WCX2 Q8N1G0 ZNF687 Zinc finger protein 687 1 LSPAT(0.185)PT(0.63)S(0.185)EGPK 144.51 0.00023967 16034000.0 99203.0 111360.0 107800.0 176860.0 148060.0 148520.0 125730.0 135950.0 125930.0 128100.0 True False 130747.4904494153 147354.9422365098 106370.50156473133 136087.65945976155 127504.424701633 139233.02092151626 136919.72642871586 114942.05132021182 132586.40270880956 123615.25799060531 1.0576970236097556 1.192044935486109 0.8604965381604868 1.1008969416227252 1.0314618662311352 1.1263417088212353 1.1076280440972883 0.9298370863647539 1.0725731181088183 1.0 16.915497302378135 -8.97710437222849 0.008167882004955654 1.835299727306666e-08 2.0569210051276605 0.03724847231509709 0.09079948923974218 13413.70218692841 47.86470437693549 6142.104454050951 5907.460832408921 1.0541335303183932e-09 8.97710437222849 2.056920986774663 LSPATPT(ph)SEGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSPATPTSEGPK 12 0 Q8N1G0;Q8N1G0-2;F8WCX2 Q8N1G0 ZNF687 Zinc finger protein 687 1 LSPAT(0.118)PT(0.554)S(0.328)EGPK 111.72 0.0025421 5135300.0 41923.0 51183.0 43379.0 53301.0 70081.0 54571.0 65161.0 56483.0 56710.0 45086.0 True False 49019.73588300693 56264.10998333715 44413.31987577364 50314.71777417354 56349.13113066784 51709.20069324489 58988.47835521334 55000.3810986854 57539.276465220515 53259.73489942034 0.9203901591996178 1.056409876796993 0.833900505882109 0.9447046229049321 1.0580062262247782 0.9708873089754654 1.1075623727119857 1.0326822167356302 1.0803522881569347 1.0 15.700757627094532 -6.253293031032961 20.897269205299175 1.0429801621319221 0.93975175908753 0.3988230139609301 0.061771393436232835 68.26732019445099 175117.992115751 0.01807585734798699 0.02280695732276432 5.580935058589226e-07 6.253293031032961 -0.10322840304439218 LSPATPT(ph)SEGPK ddPTM_PC-9_Lapatinib_30min_R1 1 LSPATPTSEGPK 12 0 Q8N1G0;Q8N1G0-2;F8WCX2 Q8N1G0 ZNF687 Zinc finger protein 687 1 LSPAT(0.03)PT(0.756)S(0.214)EGPK 126.09 0.00066977 7963000.0 55226.0 59515.0 49601.0 59842.0 80191.0 79178.0 86352.0 83599.0 76563.0 54685.0 True False 54438.46711279198 59377.19667409071 45522.997245396946 64242.98030705995 75474.32304157194 75791.74151293281 90822.88403641903 87483.31473315407 67939.66869586761 64137.22938681778 0.8487810844535919 0.9257836242969141 0.7097749260549342 1.0016488227080154 1.1767630713571842 1.181712123169923 1.4160712101961483 1.3640020869241765 1.059285992634901 1.0 15.968874412838959 -6.153090650263866 2.461924941903719 1.2344726960793422 0.8376110158522281 0.6189958334523018 0.1293645935929066 0.18262217699323138 2.1647052160619737 0.041641141184750714 0.05699072785595032 7.02925582951021e-07 6.153090650263866 -0.3968616802271141 LSPFMADIR ddPTM_PC-9_Lapatinib_30min_R1 2 LSPFMADIR 9 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 110.12 0.010704 4884600.0 46033.0 42588.0 38791.0 32154.0 37617.0 44331.0 38625.0 28593.0 37978.0 31909.0 False True 45376.5609785817 42489.39010259893 35601.75371759022 34518.71242259963 35404.44201786749 42435.06647060834 40624.813506423525 29921.535163878412 33700.51771393047 37424.428133930094 1.2124850863770973 1.1353383931624272 0.9512972005926956 0.9223577792309389 0.9460249303253555 1.1338868377292706 1.0855159459228148 0.7995188345109451 0.9004951950989623 1.0 15.191692650819206 -5.13090766620192 3.406731962645806 0.967877329869176 1.2003192279942578 0.47226196621988525 0.08878140926701092 0.2358545164309686 4.9145144484902294 0.025688434401218662 0.08717008323431522 7.397625366100028e-06 5.13090766620192 0.23244189812508187 LSPFVLSAGS(ph)GSPSATSILQK ddPTM_PC-9_AZD4547_30min_R2 1 LSPFVLSAGSGSPSATSILQK 21 0 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2 Q9UMZ2-4 SYNRG Synergin gamma 1 LSPFVLS(0.007)AGS(0.338)GS(0.274)PS(0.338)AT(0.032)S(0.01)ILQK 76.118 0.0013669 5379800.0 2237.4 1220.4 3274.8 3314.5 2907.7 4681.2 3117.2 4347.1 3312.2 3734.1 True False 2948.8466591889514 1614.8704337772667 3231.3740122836903 2550.3932335145255 2504.016045555436 4388.483823981965 3394.6247611834383 3675.3555814203187 3487.2761300096827 3603.370295571585 0.8183579308551719 0.44815556029916925 0.896764347603946 0.7077799460823854 0.6949094431490385 1.2178831105355052 0.9420693636053205 1.0199772102071223 0.9677817831532392 1.0 11.815131200688366 -6.7391934446513515 24.998334512534008 1.0253238054967353 0.7083666257554065 0.6046188390501578 0.12785712776299224 158.9302924386349 178593.71368083646 0.04068250048271151 0.04065198602785664 1.8230834785476788e-07 6.7391934446513515 -0.31695717974132875 LSPFVLSAGSGS(ph)PSATSILQK ddPTM_PC-9_AZD4547_30min_R2 1 LSPFVLSAGSGSPSATSILQK 21 0 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2 Q9UMZ2-4 SYNRG Synergin gamma 1 LSPFVLS(0.017)AGS(0.117)GS(0.657)PS(0.152)AT(0.046)S(0.011)ILQK 83.087 0.00056745 3075200.0 7672.0 6030.4 8798.4 9393.5 8505.3 11245.0 9565.7 12198.0 7962.3 9058.5 True False 10111.536412486656 7979.608869100646 8681.727467227562 7227.973703128285 7324.485907164645 10541.848372356922 10417.028768783652 10313.07938215478 8383.17092264238 8741.364672192809 1.1567457475664533 0.9128561921783921 0.9931775864293868 0.8268701712126507 0.8379110335557327 1.2059728392171578 1.1916936496107187 1.179801983889513 0.9590231316295635 1.0 13.093642810625417 -6.765168819800134 24.999970795449432 1.1238106539233979 0.9397547847621819 0.328299194846878 0.11434838325849347 106.21288377000316 711983.2456954485 0.040229884262602614 0.03683861781877571 1.717240728225745e-07 6.765168819800134 -0.18405586916121597 LSPISHGNTIALFFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSPISHGNTIALFFR 15 0 Q9BQ70 Q9BQ70 TCF25 Transcription factor 25 0 134.61 1.1805999999999998e-05 952300.0 4275.5 7700.5 4954.8 5107.5 5439.7 3806.0 6368.1 3730.8 5532.5 4043.9 False True 4999.257705025787 8464.954749168433 5072.94122318364 4821.343333738417 4373.829834213184 3606.4066599199236 5764.867466948546 3632.8704531093495 5613.40234603831 4777.027058505215 1.0465207008038406 1.7720131465650966 1.0619452561298701 1.009276957130544 0.9155966212135721 0.7549479238345383 1.2067897871092315 0.760487727747164 1.175082803025781 1.0 12.221897333349165 -5.471983697593118 11.187808037751307 0.9682452649597657 1.4116603075786593 0.39122667791687105 0.2137734717301441 0.8336827078959482 181.31951833841393 0.051395492989025 0.10672161787872544 3.3729996987924926e-06 5.471983697593118 0.44341504261889364 LSPLPPGS(ph)PGSAAR ddPTM_PC-9_AZD4547_30min_R2 2 LSPLPPGSPGSAAR 14 0 Q6ZN18-2;Q6ZN18 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 LSPLPPGS(0.57)PGS(0.43)AAR;LSPLPPGS(0.998)PGS(0.002)AAR 88.78 0.0055823 23529000.0 77818.0 60804.0 83602.0 122723.0 101191.0 77981.0 82978.0 84658.0 71558.0 92677.0 True False 102562.50528504784 80457.7039129735 82493.38285542361 94431.10840144925 87142.37633380361 73104.83574253127 90362.88125031407 71576.05134730767 75340.4097914476 89432.40643868326 1.1468158955933592 0.8996482049058693 0.922410411845317 1.055893631423115 0.974393732696327 0.8174311600644838 1.01040422424805 0.8003368599544698 0.8424285199471019 1.0 16.44851007602287 -6.5973858834103725 8.381086623831644 0.8891875349482241 0.9953790936205258 0.25259633353887656 0.09126532334893933 0.39704558494816833 39.85042431914402 0.02951877670462444 0.0295090973073061 2.5270516389694947e-07 6.5973858834103725 0.10619155867230168 LSPLPPGS(ph)PGSAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSPLPPGSPGSAAR 14 0 Q6ZN18-2;Q6ZN18 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 LSPLPPGS(0.831)PGS(0.168)AAR 105.19 0.00099476 9509900.0 36697.0 28355.0 34898.0 38420.0 40074.0 34944.0 46210.0 36612.0 30578.0 33801.0 True False 42909.07730121188 31169.897008333337 35730.100671402026 36267.451959320584 32221.787373616033 33111.475124603734 41832.65426857183 35650.97379362054 31025.14540210745 39928.85373143121 1.0746383452384132 0.7806359085083628 0.8948441373180716 0.9083018561780439 0.8069800247797164 0.8292618502729275 1.0476798194595298 0.8928624406153887 0.7770106702984328 1.0 15.285144035549543 -8.02096454901056 24.843298629118568 0.8706490966920976 0.8995568523931988 0.0 0.10288172121292916 5036.877957985478 5968733.632297018 0.06585890713550281 0.025538844225984177 9.528739429197851e-09 8.02096454901056 0.028907755701101268 LSPLPPGS(ph)PGSAAR ddPTM_PC-9_Lapatinib_30min_R1 3 LSPLPPGSPGSAAR 14 0 Q6ZN18-2;Q6ZN18 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 LSPLPPGS(0.604)PGS(0.396)AAR;LSPLPPGS(0.654)PGS(0.346)AAR;LSPLPPGS(0.586)PGS(0.414)AAR 139.77 0.00010796 26825800.0 114993.0 72383.0 101644.0 87397.0 93251.0 84725.0 64367.0 80078.0 92442.0 76072.0 True False 113353.17873286671 72215.40161069842 93287.22267718638 93824.46692784525 87766.15951851997 81101.50925362135 67699.60830985014 83798.71621911143 82030.20850258472 89220.94384043147 1.270477242827591 0.809399660015401 1.0455753846768008 1.051596888457569 0.9836945871754805 0.9089963159173541 0.7587860584721959 0.9392269641193496 0.9194052984834241 1.0 16.44509478956082 -6.671792500557916 3.3037245156520045 0.8913585510314466 1.0265906896637222 0.22615349845827293 0.11846700448049632 0.3784189303815969 8.207089840258751 0.0403351341140108 0.03950854586667568 2.1291560820997587e-07 6.671792500557916 0.13523213863227568 LSPLPPGSPGS(ph)AAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSPLPPGSPGSAAR 14 0 Q6ZN18-2;Q6ZN18 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 LSPLPPGS(0.263)PGS(0.737)AAR 152.88 0.00025743 9524400.0 25623.0 27875.0 28921.0 31990.0 37723.0 36792.0 43003.0 37257.0 36023.0 25986.0 True False 29960.46782268176 30642.245780542817 29610.586323503267 30197.704012979324 30331.448946821307 34862.56275138565 38929.44452524119 36279.04322705452 36549.76822617947 30697.056094937176 0.9760045956857439 0.9982144765209782 0.9646067112079487 0.9837328999753755 0.9880898302760646 1.135697268284156 1.2681816915877406 1.181841122316546 1.1906603718982542 1.0 14.905812684627522 -6.813968092417476 3.999789550144603 1.178301294001675 0.9808661693908115 0.6439749504451742 0.06392816991681011 0.12149399144410812 3.989227922745519 0.021782539120810705 0.019647215053058446 1.534729735134096e-07 6.813968092417476 -0.19743512461086354 LSPPVASGGIPHQS(ph)PPTK ddPTM_PC-9_AZD4547_30min_R2 2 LSPPVASGGIPHQSPPTK 18 0 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 LSPPVASGGIPHQS(0.975)PPT(0.025)K;LSPPVASGGIPHQS(0.999)PPT(0.001)K 102.9 0.00024678 43720000.0 132427.0 110013.0 216939.0 260299.0 253772.0 242088.0 174470.0 256909.0 182191.0 216229.0 True False 174536.03134728482 145572.55082853025 214062.24711457573 200291.08712946056 218540.1382235764 226950.1990900082 189997.4920068252 217209.61723151407 191821.24430970167 208658.88852498544 0.8364658346504389 0.6976580382344889 1.0258956549983889 0.9598972205081842 1.0473559969979795 1.0876613054652233 0.9105650535662387 1.0409794606257798 0.9193054063773201 1.0 17.67078685277972 -5.268102026605396 24.999283416155333 1.0007656961872933 0.7670619319162801 0.6933235133043789 0.06168203279045607 239.58339138284092 898956.6462310434 0.01540743813991783 0.033295123006189045 5.393838929006969e-06 5.268102026605396 -0.23370376427101314 LSPPVASGGIPHQS(ph)PPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSPPVASGGIPHQSPPTK 18 0 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 LSPPVASGGIPHQS(0.999)PPT(0.001)K;LSPPVASGGIPHQS(0.997)PPT(0.003)K 111.44 0.00011443 23649000.0 78398.0 91946.0 119386.0 125846.0 135804.0 116164.0 125804.0 117807.0 101770.0 95709.0 True False 91669.23296891879 101073.79123005534 122232.61501392626 118795.25661823711 109194.18107717125 110072.15534496539 113886.93437791408 114714.69107683425 103258.19372007548 113060.28406797267 0.8107995988565408 0.8939814017209531 1.0811277896705012 1.0507249083755754 0.9658049418266357 0.9735704827947292 1.0073115888285264 1.0146329634893447 0.9133020898655791 1.0 16.78673270136978 -5.030759926764724 4.83356228733694 1.0010184675111615 0.8255530546485693 0.6665480881573478 0.04378985231468779 0.10193321521793619 6.143235451996781 0.011654359634789172 0.038305720144920515 9.316227239965443e-06 5.030759926764724 -0.1754654128625922 LSPPVASGGIPHQS(ph)PPTK ddPTM_PC-9_Lapatinib_30min_R1 2 LSPPVASGGIPHQSPPTK 18 0 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 LSPPVASGGIPHQS(0.971)PPT(0.029)K;LSPPVASGGIPHQS(0.893)PPT(0.107)K 91.565 0.00069443 23980300.0 110191.0 103419.0 140105.0 116471.0 139969.0 131617.0 98654.0 114157.0 138057.0 107435.0 True False 108619.65613344559 103179.53965954417 128586.10772094016 125036.6658758661 131736.29860964188 125988.04772421236 103761.8214022706 119461.15097061767 122507.56685534008 126004.99660186101 0.8620265788082355 0.8188527633198657 1.020484196569083 0.992315140255473 1.045484720148758 0.9998654904320802 0.8234738637399249 0.9480667766539451 0.9722437217504017 1.0 16.94312141792232 -5.254181876857091 24.858333343816966 0.9719645618187899 0.8404396575709224 0.4654620559371122 0.05769802972620372 504.6700032007739 1728579.829496454 0.01617057357189214 0.04097246747107032 5.5695245567067485e-06 5.254181876857091 -0.13152490424786745 LSPPYS(ph)SPQEFAQDVGR ddPTM_PC-9_AZD4547_30min_R2 2 LSPPYSSPQEFAQDVGR 17 0 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 LSPPYS(0.578)S(0.422)PQEFAQDVGR;LSPPYS(0.599)S(0.401)PQEFAQDVGR 147.53 3.8535e-05 10443300.0 23279.2 20136.3 29687.6 35493.1 25725.8 29441.0 22000.8 28777.8 22102.1 26011.7 True False 30681.501362559866 26644.9651881917 29293.923026466757 27310.714157928618 22154.216729631673 27600.049615879077 23958.828578802953 24330.852258056555 23270.371883668562 25101.038300345277 1.2223200090546782 1.0615084869945475 1.1670402903637578 1.0880312531754093 0.8826016065370065 1.0995580854318454 0.9544955189552213 0.9693165663876889 0.9270680999418445 1.0 14.615459421804278 -6.051409386167534 6.388126817460829 0.9763061820769445 1.1395766844711914 0.6150392736825483 0.06419592003132939 0.1482055280651641 14.252390139225014 0.018106742163846834 0.0238616111647325 8.883633104884069e-07 6.051409386167534 0.1632705023942469 LSPPYSS(ph)PQEFAQDVGR ddPTM_PC-9_AZD4547_30min_R2 1 LSPPYSSPQEFAQDVGR 17 0 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 LSPPYS(0.014)S(0.986)PQEFAQDVGR 101.3 0.0080458 0.0 4801.1 4989.1 4151.3 6455.9 4844.8 3835.8 5860.1 4293.4 2904.7 5501.0 True False 6327.749930916275 6601.729007831987 4096.251049588768 4967.591997660713 4172.183147335342 3595.9468196253156 6381.637547482053 3629.9536825170794 3058.23651193742 5308.411664374089 1.1920232135316837 1.2436354648486727 0.771652861265377 0.9357963006146092 0.7859569700171852 0.6774054174732719 1.2021745770605203 0.6838116393418566 0.5761114068190893 1.0 12.374064539907094 -5.258706955045409 24.951575329894645 0.827995439109335 1.2178293802586193 0.45089791543834734 0.1715815141420617 201.25379649359306 1837756.3426573926 0.04417700947085863 0.1065190516884284 5.511794853468246e-06 5.258706955045409 0.38983394114928427 LSPPYSS(ph)PQEFAQDVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSPPYSSPQEFAQDVGR 17 0 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 LS(0.001)PPY(0.003)S(0.405)S(0.591)PQEFAQDVGR;LSPPYS(0.241)S(0.759)PQEFAQDVGR 122.5 5.7373e-05 5794000.0 13425.0 20156.2 17984.3 16841.3 19519.9 17881.4 18322.1 15175.0 15280.7 13308.4 True False 15697.587344163549 22157.174328314864 18413.11391783756 15897.736561231293 15695.115719774609 16943.667905594364 16586.49804748322 14776.672329241554 15504.151329255781 15721.107570763572 0.9985039077880388 1.4093901608764765 1.1712351585253633 1.0112351492840235 0.9983466908503762 1.0777655346054866 1.0550464064204361 0.9399256549024334 0.9861996846894386 1.0 13.940415240311376 -5.695977918154274 4.459443057614028 1.011077388943583 1.222220380049095 0.41669822332058515 0.09898788354765285 0.17679860109245749 6.857677939088536 0.026251085487155816 0.04601275600918672 2.013826640937008e-06 5.695977918154274 0.21114299110551205 LSPPYSS(ph)PQEFAQDVGR ddPTM_PC-9_Lapatinib_30min_R1 2 LSPPYSSPQEFAQDVGR 17 0 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 LSPPY(0.001)S(0.288)S(0.711)PQEFAQDVGR;LSPPYS(0.185)S(0.815)PQEFAQDVGR 145.94 9.549e-05 8393000.0 23624.0 23521.1 31044.0 22249.5 21888.4 25635.7 25089.5 24143.7 27396.9 20682.8 True False 23287.117427888996 23466.638338082077 28491.68215330542 23885.80245215619 20600.96734625012 24539.320870735486 26388.51154613368 25265.50444291021 24311.17261985313 24257.79442190134 0.959984944338717 0.9673854897910684 1.1745372088561143 0.9846650539090522 0.849251460703714 1.0116056078280542 1.08783639135422 1.041541700101929 1.0022004555329067 1.0 14.566160762603198 -7.003449012583671 24.999480223525868 1.0382656742209282 0.9897458772123613 0.0693937481950192 0.07780165955986235 440.8894392009029 3195706.1487261457 0.02995729691310413 0.025896978200922457 9.920898065875499e-08 7.003449012583671 -0.0485197970085669 LSPQDPRPLS(ph)PGALQLAGEK ddPTM_PC-9_AZD4547_30min_R2 2 LSPQDPRPLSPGALQLAGEK 20 1 Q8TEK3-1;Q8TEK3 Q8TEK3-1 DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 1 LSPQDPRPLS(1)PGALQLAGEK;LS(0.001)PQDPRPLS(0.999)PGALQLAGEK 81.553 0.00058104 16554900.0 135883.0 105873.0 164482.0 221158.0 198060.0 161954.0 146946.0 167830.0 157223.0 170143.0 True False 179090.9674580196 140094.37679064265 162300.86120937037 170173.43995703882 170562.78776445668 151826.99077782966 160023.9093278779 141895.72984973254 165533.4868028839 164186.3453574985 1.0907786945867382 0.8532644811942302 0.9885161939379143 1.0364652406782309 1.038836618191812 0.9247236147880773 0.9746480986554799 0.8642358750404578 1.008204954208903 1.0 17.3249746240607 -6.7788250279595195 24.931225421546127 0.9471451022270962 0.9945461026128284 0.09610967508093105 0.06901555177837106 589.9634203076305 846009.1413998534 0.02401229498071832 0.021226064490422598 1.6640829544058445e-07 6.7788250279595195 0.04740100038573214 LSPQDPRPLS(ph)PGALQLAGEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSPQDPRPLSPGALQLAGEK 20 1 Q8TEK3-1;Q8TEK3 Q8TEK3-1 DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 1 LSPQDPRPLS(1)PGALQLAGEK 50.236999999999995 0.023998 4438900.0 31861.0 23633.0 33185.0 39548.0 38866.0 37797.0 35078.0 35095.0 36266.0 29349.0 True False 37254.43801656571 25979.128054944147 33976.25625481335 37332.25377634595 31250.486301915458 35814.85878218429 31755.157897272504 34173.7934362262 36796.32164146864 34669.74137344385 1.0745519447428493 0.7493314638580922 0.9799973956782472 1.0767964310498581 0.9013763894371748 1.0330293034610742 0.9159329328483585 0.9856950782564091 1.0613382212782727 1.0 15.081389454029576 -5.491193016132406 24.98912355003782 0.9928974362508427 0.9001223788957831 0.11697546076800669 0.0899440269364239 1134.3494602509095 894609.2488579082 0.02190738295139268 0.04553180796819038 3.2270595812801644e-06 5.491193016132406 -0.09277505735505964 LSPQDPRPLS(ph)PGALQLAGEK ddPTM_PC-9_Lapatinib_30min_R1 2 LSPQDPRPLSPGALQLAGEK 20 1 Q8TEK3-1;Q8TEK3 Q8TEK3-1 DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 1 LSPQDPRPLS(1)PGALQLAGEK;LSPQDPRPLS(1)PGALQLAGEK 64.152 0.0060893 5758000.0 79429.0 60785.0 65906.0 69771.0 71016.0 61824.0 54863.0 45717.0 69709.0 60941.0 True False 78296.32789450535 60644.25606711924 60487.46308451708 74902.19208923283 66838.97850282793 59179.93163878305 57703.53769327931 47841.17871811385 61857.63835168725 71474.5706512217 1.0954431370643993 0.8484731774472388 0.8462794884026796 1.0479558171078367 0.9351434768175899 0.827985829079919 0.8073296162191496 0.6693454508676522 0.8654495968018793 1.0 16.125142428141903 -6.77435860900469 4.274121794519766 0.809639105605593 0.9491471092019205 0.23318627187950758 0.10534156941251165 0.27643157352183384 11.702517233009994 0.03686956853964355 0.034109348040747285 1.6812852038945764e-07 6.77435860900469 0.13950800359632742 LSPS(ph)PSLR ddPTM_PC-9_AZD4547_30min_R2 1 LSPSPSLR 8 0 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 LS(0.001)PS(0.849)PS(0.151)LR 89.029 0.028094 0.0 87063.0 86727.0 83720.0 101780.0 103580.0 106020.0 95515.0 99535.0 97453.0 84665.0 True False 114747.22297710208 114759.80671107923 82609.8180983237 78316.19348532458 89199.70492094509 99390.55264004263 104015.64996292685 84154.1528367583 102604.1666257574 81700.90412002028 1.4044792308361251 1.4046332528033565 1.011124894982413 0.9585719317166491 1.09178357181836 1.2165171696758204 1.2731272815552415 1.0300271917815518 1.2558510549042372 1.0 16.318064423186655 -5.249157159502191 24.68844777911753 1.110037016993587 1.4045563138953383 0.564709958090176 0.10524561675971267 493.1363440410568 991246.2459072085 0.028348547818383363 0.07378370256501439 5.634337274052968e-06 5.249157159502191 0.2945192969017514 LSPS(ph)PSSR ddPTM_PC-9_AZD4547_30min_R2 2 LSPSPSSR 8 0 P20700;Q03252 P20700;Q03252 LMNB1;LMNB2 Lamin-B1;Lamin-B2 1 LS(0.001)PS(0.961)PS(0.038)SR;LSPS(0.923)PS(0.076)S(0.001)R 136.99 0.0033176000000000004 1024990000.0 1564520.0 1604510.0 2013780.0 2666500.0 2461500.0 2198000.0 1923090.0 2375900.0 1622640.0 1753130.0 True False 2062004.8159624136 2123136.479596823 1987075.961419524 2051779.6220143274 2119763.2135828002 2060558.7125336137 2094241.2844810244 2008759.2477505761 1708409.4377147844 1691753.4523112385 1.218856573424068 1.25499166364711 1.1745659266749666 1.2128124338751776 1.2529977170649917 1.2180017778113714 1.2379116363675307 1.187382975342093 1.0098453976144046 1.0 20.690087901939762 -8.227109830077126 3.4233156488782672 0.9960110966469783 1.2235295828077664 0.9406973959034488 0.021735814112060235 0.05071448971503417 1.164385942664328 0.018960152973020637 0.005739808593599035 5.927753968162228e-09 8.227109830077126 0.22751848616078807 LSPS(ph)PSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LSPSPSSR 8 0 P20700;Q03252 P20700;Q03252 LMNB1;LMNB2 Lamin-B1;Lamin-B2 1 LS(0.004)PS(0.833)PS(0.146)S(0.017)R;LS(0.041)PS(0.914)PS(0.045)SR;LSPS(0.959)PS(0.041)SR;LS(0.005)PS(0.772)PS(0.221)S(0.002)R 133.99 0.0033068000000000004 1138730000.0 3681540.0 3513490.0 4225210.0 4208490.0 4695700.0 4081020.0 4434320.0 3909800.0 3869720.0 3024860.0 True False 4304752.008270528 3862286.0673535215 4325955.030598163 3972701.9494086793 3775611.293364494 3867004.126974885 4014269.1079033446 3807171.892775522 3926307.3342090063 3573243.173221422 1.204718458718728 1.0808909106153881 1.210652290058989 1.1117916572767503 1.0566342984042223 1.0822112964365158 1.1234245511156522 1.0654667785577001 1.098807761988749 1.0 21.76880266764782 -1.5228787470821907 0.06732601137755749 0.8863808851798741 1.5982153489021607 0.5163505595803188 0.04260673252692515 232.97789828936885 1.1665416588881727 2.243903211260061 15.841893267824336 0.029999999875532393 1.5228787470821907 0.7118344637222865 LSPS(ph)PSSR ddPTM_PC-9_Lapatinib_30min_R1 2 LSPSPSSR 8 0 P20700;Q03252 P20700;Q03252 LMNB1;LMNB2 Lamin-B1;Lamin-B2 1 LS(0.13)PS(0.829)PS(0.041)SR;LS(0.07)PS(0.849)PS(0.08)S(0.001)R 122.94 0.0033068000000000004 901840000.0 2588300.0 2531100.0 3020000.0 2507600.0 2808600.0 2512100.0 2362900.0 2286300.0 2889500.0 2106630.0 True False 2551390.367363913 2525239.3934603166 2771707.2575371163 2692017.269108376 2643403.6699200533 2404663.338991116 2485239.400241506 2392529.8445484973 2564054.082216074 2470758.1885919697 1.0326345893111837 1.0220503993955776 1.121804339386466 1.0895510866008693 1.0698755070913963 0.9732491629872854 1.0058610396259735 0.9683383244849012 1.0377600260741306 1.0 21.236522391326368 -6.750974135876758 24.995672845657243 0.9956140644788363 1.0689529937578304 0.5539762277799029 0.03143557395490838 164.02714935200194 391769.23555085895 0.010940475488677322 0.010827806978727332 1.774295144728271e-07 6.750974135876758 0.0733389292789941 LSPS(ph)PTSQR ddPTM_PC-9_AZD4547_30min_R2 5 LSPSPTSQR 9 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 LS(0.141)PS(0.836)PT(0.023)SQR;LS(0.129)PS(0.434)PT(0.434)S(0.004)QR;LS(0.344)PS(0.656)PTSQR;LS(0.178)PS(0.765)PT(0.055)S(0.002)QR;LS(0.012)PS(0.988)PTSQR 113.67 0.0020857 431359900.0 158511.0 186139.0 262017.0 378005.0 321570.0 256092.0 211226.0 272192.0 221296.0 260798.0 True False 208914.2007663803 246304.7916034633 258542.4833811336 290861.78736903245 276925.5562022422 240078.52675621439 230024.70480101742 230130.9807499161 232993.254775262 251667.54140073265 0.8301197667510257 0.9786911344727995 1.0273175553038598 1.155738184392601 1.1003626238843847 0.9539510952424931 0.9140022726838137 0.9144245597547136 0.9257977944969256 1.0 17.941159632612866 -6.978537454393016 23.46985230071899 0.931789401775739 1.0246374888896914 0.1760098905396883 0.08257335385316218 197.56959073520161 216045.5820414062 0.031743219945835725 0.027991363586181428 1.050660839942718e-07 6.978537454393016 0.09284808711395243 LSPS(ph)PTSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LSPSPTSQR 9 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 LS(0.125)PS(0.873)PT(0.002)SQR;LS(0.125)PS(0.865)PT(0.01)SQR;LS(0.006)PS(0.977)PT(0.013)S(0.004)QR;LSPS(0.988)PT(0.002)S(0.01)QR;LSPS(0.984)PT(0.016)SQR;LS(0.001)PS(0.851)PT(0.148)SQR 133.91 0.001145 3957191900.0 404738.0 440580.0 448331.0 461994.0 522123.0 447277.0 471918.0 459087.0 434250.0 343735.0 True False 473252.1494601156 484317.870708217 459020.9113447849 436109.9739847574 419816.74624131713 423821.00673384266 427214.5106495539 447036.4526928842 440600.08472971234 406051.4344952367 1.1654980361008112 1.1927500547074126 1.1304501655446548 1.0740264334415823 1.0339004140280703 1.043761875292216 1.0521192005653792 1.1009355335700168 1.085084418621555 1.0 18.631302959461266 -5.63249124880794 2.453666270867825 1.0569936262750328 1.1787113916121983 0.7806525492512368 0.026931539148157827 0.13345748637403543 1.6177932898255858 0.008076389758190635 0.016696374494981125 2.330820081683397e-06 5.63249124880794 0.1217177653371655 LSPS(ph)PTSQR ddPTM_PC-9_Lapatinib_30min_R1 4 LSPSPTSQR 9 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 LS(0.003)PS(0.989)PT(0.007)SQR;LS(0.044)PS(0.945)PT(0.01)SQR;LS(0.049)PS(0.903)PT(0.015)S(0.033)QR;LS(0.076)PS(0.922)PT(0.002)SQR 128.51 0.0013277 6235917000.0 778466.0 688196.0 776151.0 655994.0 621681.0 695183.0 747690.0 617262.0 708750.0 536527.0 True False 767364.9320868208 686602.5244446348 712338.860809501 704237.9870918344 585114.9458518723 665451.6436407233 786401.7297247333 645942.2459457177 628923.111531629 629264.9770727097 1.219462325166325 1.0911182879407253 1.1320173325444622 1.1191437832245061 0.929838727993063 1.057506245995687 1.2497147598822538 1.0265027762240786 0.9994567224404081 1.0 19.263308123671912 -1.5228788667410038 0.6548727649293623 1.0588864831032838 14.880833523166316 0.2567808461604719 0.08240028766762558 367.6564641194467 2.3293777329706282 0.03624957689806413 7375.265297901171 0.02999999160979559 1.5228788667410038 13.821947040063034 LSPS(ph)PTTEDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSPSPTTEDPR 11 0 F6RRE2;E7EV10;Q9BTC8;E7EQY4;Q9BTC8-2 F6RRE2 MTA3 Metastasis-associated protein MTA3 1 LS(0.002)PS(0.571)PT(0.282)T(0.145)EDPR;LSPS(0.558)PT(0.221)T(0.221)EDPR 109.16 0.0020958 10794500.0 60866.0 72774.0 75063.0 61770.0 66113.0 57932.0 74031.0 54504.0 54797.0 46095.0 True False 71169.41164170258 79998.52177338912 76852.7865980126 58309.22716104196 53158.63224614159 54893.943936542586 67018.24774197457 53073.327751761586 55598.302459260965 54451.65861218079 1.307020088195845 1.4691659319904264 1.4113947776206157 1.0708439126957694 0.9762536826426449 1.0081225317214277 1.23078432227926 0.9746870729827342 1.0210580150596857 1.0 15.73268837404028 -5.778926859749418 6.0447569644321 1.0416022272975605 1.4048052697765756 0.8109116793505771 0.07872035006725468 0.06416221549618051 8.00964646654508 0.022427064858484835 0.03528231484698585 1.6636928120309764e-06 5.778926859749418 0.36320304247901514 LSPS(ph)PTTEDPR ddPTM_PC-9_Lapatinib_30min_R1 2 LSPSPTTEDPR 11 0 F6RRE2;E7EV10;Q9BTC8;E7EQY4;Q9BTC8-2 F6RRE2 MTA3 Metastasis-associated protein MTA3 1 LS(0.001)PS(0.509)PT(0.245)T(0.245)EDPR;LS(0.006)PS(0.644)PT(0.025)T(0.325)EDPR 123.01 0.00061307 22873000.0 153920.0 144094.0 134332.0 126353.0 143345.0 141477.0 148857.0 147788.0 152975.0 119160.0 True False 151725.0725745289 143760.35919610914 123287.7414965153 135645.42112125183 134913.7289271132 135426.35850899492 156564.08709710522 154654.7700066191 135745.34460183568 139756.64722928024 1.0856376106791805 1.0286477390965207 0.882160125766708 0.9705829655366327 0.9653474922432713 0.9690155079838085 1.1202621857424158 1.1066004592461172 0.971297947489655 1.0 17.092557377874883 -7.234002969235803 24.560673940995365 1.0584235303700038 0.9795869294526978 0.19784261878402654 0.06378910222891679 853.2455234873416 763814.1738496302 0.0253161691646491 0.019604480854396235 5.8344111532098847e-08 7.234002969235803 -0.07883660091730604 LSPS(ph)TSGPHSHDYLPQER ddPTM_PC-9_AZD4547_30min_R2 1 LSPSTSGPHSHDYLPQER 18 0 Q5JR04;Q9HCE1 Q5JR04 MOV10 Putative helicase MOV-10 1 LS(0.105)PS(0.703)T(0.184)S(0.008)GPHSHDYLPQER 113.33 8.9348e-05 11562000.0 4112.2 5214.2 8077.1 12299.0 10095.0 9779.3 6099.1 14045.0 8069.3 10098.0 True False 5419.794060926435 6899.58818076157 7969.992376516618 9463.655567655798 8693.483502384062 9167.798825059135 6641.90808447771 11874.667971992458 8495.826724197554 9744.47209359199 0.5561916550092556 0.7080515100760328 0.8178988353568913 0.971181966222587 0.8921451484376396 0.9408204710327942 0.6816077895944163 1.2186055702084975 0.8718611580594959 1.0 13.25036831431287 -4.922031237441152 1.0423877037935743 0.9416061055740831 0.4122551473346977 0.49920164720990623 0.1259791345407723 1.2490745207986031 1.2948766903527673 0.04076867011609488 0.6998008035318185 1.1966544566065844e-05 4.922031237441152 -0.5293509582393854 LSPS(ph)TSGPHSHDYLPQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSPSTSGPHSHDYLPQER 18 0 Q5JR04;Q9HCE1 Q5JR04 MOV10 Putative helicase MOV-10 1 LS(0.41)PS(0.492)T(0.082)S(0.015)GPHSHDYLPQER 66.02199999999999 0.012403 6229300.0 3551.2 9802.6 19830.0 18981.0 27298.0 13994.0 9739.0 10678.0 17407.0 10633.0 True False 4152.348020602872 10775.737344873505 20302.82240569379 17917.556107232293 21949.15286033265 13260.130004970935 8816.451415745969 10397.713814276201 17661.544444191375 12560.678729218316 0.33058309269098574 0.8578945116880724 1.616379404599045 1.4264799294287298 1.7474495872006595 1.0556857866387088 0.7019088383526102 0.8277987231764249 1.4060979366590725 1.0 13.616626803398486 -11.130140721715357 7.8280431623754065 0.9998973177564888 1.1218950062461326 0.004870125970179218 0.42101212647768516 0.0008144509336152241 4.086145100169297e-05 0.43992611664069387 0.10660828925342808 7.41070078107249e-12 11.130140721715357 0.12199768848964376 LSPSPTS(ph)QR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSPSPTSQR 9 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 LS(0.01)PS(0.027)PT(0.04)S(0.923)QR 99.973 0.0039689999999999994 4348000.0 4447.3 36287.0 9578.0 21294.0 11570.0 7546.5 14480.0 8614.5 9511.9 9082.4 True False 5200.140051821123 39889.333547571565 9806.375844767272 20100.966216079465 9302.941555939951 7150.748255146008 13108.349573878382 8388.378502817226 9650.99354275314 10728.96722376116 0.48468225723576736 3.7179099083488403 0.9140093021301576 1.8735229399864683 0.8670863990838721 0.6664898965586767 1.2217717978341538 0.7818439862729477 0.8995267989428973 1.0 13.389223587715737 -5.994063681394472 1.558743083993882 0.896773620252402 1.9874956728861968 0.18561128521492054 0.8106774608172905 0.5537393998665712 2.7199863269180744 0.26023399583722545 0.45029137319994633 1.0137627249545915e-06 5.994063681394472 1.0907220526337946 LSPSTS(ph)GPHSHDYLPQER ddPTM_PC-9_AZD4547_30min_R2 1 LSPSTSGPHSHDYLPQER 18 0 Q5JR04;Q9HCE1 Q5JR04 MOV10 Putative helicase MOV-10 1 LS(0.05)PS(0.289)T(0.289)S(0.372)GPHSHDYLPQER 88.19 0.00088772 8622600.0 5824.0 6567.7 7326.5 14878.0 10536.0 12550.0 6892.1 10885.0 6473.8 11248.0 True False 7675.910853274541 8690.580586626473 7229.345822949942 11448.106962808612 9073.25826459816 11765.246516058636 7505.483548233154 9202.973362416365 6815.991851475359 10854.21094362474 0.7071827600497312 0.8006644270840265 0.6660406602099552 1.0547157248249999 0.8359205760532388 1.0839338370302263 0.6914812681654696 0.8478712464881444 0.627958299951666 1.0 13.4059672313343 -5.716850810759937 24.99998815768778 0.8702030734494799 0.7322327956239655 0.19624646988785133 0.14091240824609003 243.77416971939962 136677.80800866598 0.03784685759500883 0.06555232928720248 1.919327956742423e-06 5.716850810759937 -0.1379702778255144 LSPSTS(ph)GPHSHDYLPQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSPSTSGPHSHDYLPQER 18 0 Q5JR04;Q9HCE1 Q5JR04 MOV10 Putative helicase MOV-10 1 LS(0.198)PS(0.198)T(0.198)S(0.405)GPHS(0.001)HDYLPQER 54.073 0.02482 6195600.0 9815.5 12557.0 12642.0 11495.0 16455.0 13726.0 11243.0 12531.0 14715.0 12377.0 True False 11477.07028503816 13803.57597367807 12943.433225051976 10850.972417292818 13230.76087320586 13006.184396757986 10177.981647728908 12202.074527691992 14930.179036955025 14620.852123721901 0.7849795749193682 0.9441020165495125 0.8852721520965005 0.742157319250048 0.9049240605983109 0.889564047751761 0.6961278016905343 0.8345665782293554 1.0211565584971105 1.0 13.835739775575973 -8.259765175575113 24.62358319200374 1.0105783020488313 0.8369075970797933 0.4815506814863343 0.0727674942388195 102.53301547399667 1508093.1578627091 0.05665782180531534 0.018889731678800568 5.498380927241169e-09 8.259765175575113 -0.17367070496903791 LSPT(ph)FPESIEHPLAR ddPTM_PC-9_Lapatinib_30min_R1 1 LSPTFPESIEHPLAR 15 0 M9T4I7;Q5U5Q3 M9T4I7 MEX3C RNA-binding E3 ubiquitin-protein ligase MEX3C 1 LS(0.414)PT(0.586)FPESIEHPLAR 119.04 0.00021679 1615300.0 3866.6 5962.1 5253.6 6537.7 7538.2 6925.2 5582.9 8054.5 6810.0 7089.4 True False 3811.461574952401 5948.295123760331 4821.669287482459 7018.504267127874 7094.817896671421 6629.025339429675 5871.955244660505 8428.741474397879 6042.986087520845 8314.793343968287 0.45839522610833244 0.7153870069513321 0.5798904540399903 0.844098461234666 0.8532765161046534 0.7972567765906652 0.7062057951109675 1.0137042648825725 0.7267752591715998 1.0 13.021464691850266 -4.132326824166569 0.40942653039069626 0.884618561283094 1.0712268865553446e-19 0.5600179646343071 0.10851125689612687 7.248926831555204 0.6363507046892403 0.07986170150747474 3.4855155811347625 7.373491362362739e-05 4.132326824166569 -0.884618561283094 LSPVIS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 LSPVISPR 8 0 Q08499-7;Q08499-12;Q08499-6 Q08499-7 PDE4D cAMP-specific 3,5-cyclic phosphodiesterase 4D 1 LS(0.001)PVIS(0.999)PR 70.399 0.038245 6664100.0 18323.0 22601.0 26753.0 57634.0 45876.0 32618.0 23418.0 44047.0 36317.0 38692.0 True False 24149.33285792401 29906.331263356282 26398.237739900334 44347.371736423665 39506.9092774018 30578.391303649438 25502.156633322782 37240.54824936646 38236.64247737503 37337.40485692821 0.6467865924388941 0.8009750912778545 0.7070185472465145 1.187746494603915 1.0581053886521259 0.8189747364826672 0.6830189921084107 0.9974059094912223 1.024084095396897 1.0 15.188334035818686 -5.696932743198381 24.999999501320275 0.9527326087597853 0.7265299156964632 0.41816235939075874 0.13363183327398673 71.76897217279131 27813.42806201675 0.03973325941180756 0.06882000725378486 2.0094039738736015e-06 5.696932743198381 -0.22620269306332208 LSPVIS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 LSPVISPR 8 0 Q08499-7;Q08499-12;Q08499-6 Q08499-7 PDE4D cAMP-specific 3,5-cyclic phosphodiesterase 4D 1 LSPVIS(1)PR 75.509 0.026271 6438600.0 17814.0 18500.0 21568.0 17805.0 18693.0 20198.0 16954.0 19156.0 23442.0 18393.0 True False 17559.969093312502 18457.164386636603 19794.76229488763 19114.43909573883 17593.514491852 19334.178623837666 17831.795163440893 20046.057692416136 20801.715104796418 21572.205542868058 0.8140089829209868 0.8555993196874896 0.9176049363868561 0.8860679107546431 0.8155640116116248 0.8962541445016826 0.8266097376091536 0.9292539723201145 0.9642831866894402 1.0 14.396886064767918 -8.08462606478333 2.3467791557034143 0.9882848788159208 0.861792577595194 0.6805053746293297 0.034144247832259944 0.18555414050873323 1.8456723892353901 0.029343565651183023 0.009399483403817419 8.229509202587676e-09 8.08462606478333 -0.12649230122072674 LSQLEEER ddPTM_PC-9_AZD4547_30min_R2 3 LSQLEEER 8 0 E7EQ67;H7BY63;H0YBA5;A0A087X2A7;Q8NB25-4;Q8NB25-2;Q8NB25-3;Q8NB25 E7EQ67 FAM184A Protein FAM184A 0 ;; 115.49 0.016732 35639700.0 51769.7 65152.2 69211.0 100106.0 98655.0 72637.1 61370.6 86239.0 64006.9 72637.7 False True 68231.38772334595 86211.37452928814 68293.21691833595 77028.10832228238 84958.45615925718 68095.09065431086 66832.46450939431 72912.74412507364 67390.17406132384 70094.67623219504 0.9734175459677312 1.2299275660209208 0.9742996271515459 1.0989152452480087 1.2120529079530165 0.9714730749128455 0.9534599216637459 1.0402037364941026 0.9614164396463964 1.0 16.097017253670117 -6.809873084848327 24.999988298185347 0.9858325156176183 1.0982771721912248 0.3228783407393526 0.08139093220562302 138.31415270271427 71392.50928256614 0.027523287622772435 0.024273297537654732 1.549269300281824e-07 6.809873084848327 0.11244465657360647 LSQLEEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LSQLEEER 8 0 E7EQ67;H7BY63;H0YBA5;A0A087X2A7;Q8NB25-4;Q8NB25-2;Q8NB25-3;Q8NB25 E7EQ67 FAM184A Protein FAM184A 0 ;; 122.18 0.015388999999999998 31784000.0 61179.0 52275.5 67613.0 76041.0 90377.0 65974.0 81124.0 71679.0 65297.0 61802.4 False True 71535.39635967086 57465.06616325618 69225.15034373046 71780.66929824818 72668.27562672294 62514.207299410664 73439.34743310149 69797.50220017829 66251.84509521248 73006.68589247084 0.9798471946121895 0.7871205967066441 0.9482028871395413 0.9832067901831838 0.9953646674737937 0.8562805794456387 1.0059263276416615 0.9560426055084976 0.9074764082948877 1.0 16.155740970421903 -1.5228787452803376 0.17311451311801898 0.9823463463560584 0.6288114397572176 0.07444923648132395 0.06538562697625531 146.388061338246 1.605091950251578 0.1628866673794717 13.465818786371402 0.029999999999999995 1.5228787452803376 -0.3535349065988408 LSQLEEER ddPTM_PC-9_Lapatinib_30min_R1 2 LSQLEEER 8 0 E7EQ67;H7BY63;H0YBA5;A0A087X2A7;Q8NB25-4;Q8NB25-2;Q8NB25-3;Q8NB25 E7EQ67 FAM184A Protein FAM184A 0 ; 127.46 0.016649 38992000.0 105151.0 91421.0 123442.0 79527.0 110976.0 92191.0 80203.0 96896.0 116908.0 88701.0 False True 103651.52745766804 91209.32029138935 113293.07525989987 85375.68087429504 104448.60986721075 88248.20583771743 84355.51890370701 101398.1418962391 103740.58994418303 104032.84966334683 0.9963345980917301 0.8767357674671531 1.0890125150519223 0.8206607927262696 1.003996431946345 0.8482725035725835 0.8108546404014096 0.9746742709092973 0.9971906977448992 1.0 16.666679623604182 -7.982286219065997 24.996621938304965 0.9943744759096791 0.9200645935637608 0.13070891805381646 0.08383559252132314 465.0915509344302 656308.8563883682 0.04494932303006486 0.02158635960501589 1.0416307229107176e-08 7.982286219065997 -0.07430988234591829 LSQNSVNLS(ph)PSSHANNLSVVTYSK ddPTM_PC-9_AZD4547_30min_R2 2 LSQNSVNLSPSSHANNLSVVTYSK 24 0 Q5TH58;Q9H6K1-2;Q9H6K1 Q5TH58 C6orf106 Uncharacterized protein C6orf106 1 LS(0.002)QNS(0.032)VNLS(0.484)PS(0.415)S(0.067)HANNLSVVTYSK;LSQNS(0.011)VNLS(0.933)PS(0.041)S(0.015)HANNLSVVTYSK 112.06 1.8095e-07 33955000.0 28566.0 26509.1 80687.0 158383.0 112281.0 94805.0 56109.0 100000.0 64392.0 93465.0 True False 37649.39379028855 35077.6481612954 79617.03766005074 121870.24634295706 96692.72126113749 88876.82836294337 61102.592302464225 84547.29777139511 67795.6296611265 90192.81879853169 0.41743227777798947 0.388918415330273 0.8827425367189753 1.3512189547505424 1.0720667404477617 0.9854091439527141 0.6774662674525365 0.9374060917228092 0.7516743634830292 1.0 16.460724949436084 -5.299093777726521 4.872996599187789 0.9679227265236776 0.3982968869576164 0.627042216834939 0.17155216964762887 0.12418118309540944 7.426403449201684 0.04958420287828827 0.11339414836391702 5.022341297970017e-06 5.299093777726521 -0.5696258395660612 LSQNSVNLS(ph)PSSHANNLSVVTYSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSQNSVNLSPSSHANNLSVVTYSK 24 0 Q5TH58;Q9H6K1-2;Q9H6K1 Q5TH58 C6orf106 Uncharacterized protein C6orf106 1 LSQNS(0.004)VNLS(0.558)PS(0.18)S(0.258)HANNLSVVTYSK;LS(0.023)QNS(0.12)VNLS(0.683)PS(0.12)S(0.052)HANNLS(0.002)VVT(0.001)YSK 90.211 7.4922e-06 20469800.0 25285.0 31568.0 53562.0 58437.0 71079.0 70717.0 60802.0 59473.0 59812.0 43835.0 True False 29565.251098486064 34701.862414356074 54839.121215016145 55162.96434531018 57151.58019487083 67008.47602983643 55042.39439164045 57911.89676685224 60686.63734681307 51781.93850233095 0.5709568230466148 0.6701537914188743 1.0590395570561264 1.065293535560223 1.1036971934200217 1.2940511299479462 1.0629651184102105 1.118380239168631 1.1719653435547084 1.0 15.66016135435393 -5.233895548504868 2.275170094188449 1.1270209096569923 0.5608016818060655 0.8761893357804001 0.07414622837542935 0.10192166646111508 0.9751758267760997 0.020380415595829513 0.0768003945403384 5.835854446305647e-06 5.233895548504868 -0.5662192278509268 LSQNSVNLS(ph)PSSHANNLSVVTYSK ddPTM_PC-9_Lapatinib_30min_R1 1 LSQNSVNLSPSSHANNLSVVTYSK 24 0 Q5TH58;Q9H6K1-2;Q9H6K1 Q5TH58 C6orf106 Uncharacterized protein C6orf106 1 LSQNS(0.006)VNLS(0.434)PS(0.229)S(0.33)HANNLSVVTYSK 118.41 7.9013e-09 10975000.0 47384.0 27957.0 77438.0 45558.0 62394.0 69830.0 43827.0 43659.0 89816.0 44555.0 True False 46708.2954708386 27892.267284172965 71071.34655932427 48908.487297032836 58724.10759132375 66843.53368168055 46096.147612842055 45687.556525015476 79699.97627559066 52256.27238419431 0.8938313687481128 0.5337592218424175 1.3600538905033124 0.9359352488338977 1.1237714615305345 1.2791485238410993 0.8821170265253081 0.8742980400346038 1.5251753069875895 1.0 15.673316595584318 -5.255068547884008 24.997890913619763 1.1084560294581403 0.7137952958827251 0.35695901620655535 0.2188009240707132 543.0543356405625 2130823.761165031 0.053813056658520736 0.13528611951553232 5.5581652174758825e-06 5.255068547884008 -0.3946607335754152 LSQNSVNLSPS(ph)SHANNLSVVTYSK ddPTM_PC-9_Lapatinib_30min_R1 1 LSQNSVNLSPSSHANNLSVVTYSK 24 0 Q5TH58;Q9H6K1-2;Q9H6K1 Q5TH58 C6orf106 Uncharacterized protein C6orf106 1 LS(0.001)QNS(0.009)VNLS(0.072)PS(0.773)S(0.138)HANNLS(0.005)VVT(0.002)YSK 70.15 0.00043226 13410000.0 21494.0 12746.0 33827.0 18585.0 28583.0 29441.0 17639.0 20850.0 35572.0 20552.0 True False 21187.49161848315 12716.487420111913 31045.87463599609 19951.80289774255 26901.80413634015 28181.877060323044 18552.26111171014 21818.767116667186 31565.506770233696 24104.385816181377 0.8789890678010926 0.5275590723234806 1.2879761746575953 0.8277250061417794 1.1160543289296694 1.169159723680013 0.7696632991683998 0.9051783058508861 1.3095337508680116 1.0 14.55700804963881 -5.25301013918388 24.976732495111847 1.0337018748714057 0.7032740828289392 0.3454612518100265 0.1890550105086153 686.5375486087305 2034272.031804714 0.04668914374248365 0.11922082585864699 5.584571566575229e-06 5.25301013918388 -0.33042779204246653 LSQSSQDS(ph)SPVR ddPTM_PC-9_AZD4547_30min_R2 1 LSQSSQDSSPVR 12 0 O95251-2;O95251-4;O95251 O95251-2 KAT7 Histone acetyltransferase KAT7 1 LSQSS(0.001)QDS(0.704)S(0.294)PVR 143.56 8.5802e-05 24238000.0 27307.0 30152.0 48156.0 50977.0 39944.0 46891.0 34547.0 52166.0 37489.0 39934.0 True False 35990.05797911538 39898.044345503215 47517.41997542854 39225.04023679892 34398.46508362843 43958.89835733112 37621.616073593024 44104.94335542599 39470.592004689606 38535.92281496359 0.9339352829806986 1.035346799324881 1.2330681739111593 1.017882468395638 0.8926337445919791 1.1407252025183572 0.9762739108192438 1.1445150429432545 1.0242544909126474 1.0 15.23391631896219 -7.7265779545288495 24.999916673723845 1.0632894922820948 1.0388174963414973 0.0077048945300273175 0.09847710498351565 1265.703410140384 907664.1914222686 0.04721508699484436 0.027257922873042115 1.8768175051467634e-08 7.7265779545288495 -0.024471995940597457 LSQSSQDS(ph)SPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSQSSQDSSPVR 12 0 O95251-2;O95251-4;O95251 O95251-2 KAT7 Histone acetyltransferase KAT7 1 LSQSSQDS(0.675)S(0.324)PVR 138.21 6.8742e-05 35065000.0 37814.0 36807.0 49857.0 50420.0 59457.0 36568.0 39668.0 39004.0 35662.0 32049.0 True False 44215.16333945624 40460.955711011295 51045.77996372544 47595.13086384549 47806.82766564576 34650.30970571513 35910.35986855028 37980.18632815404 36183.48928412438 37859.23000025561 1.167883323014169 1.0687210413613304 1.3483047585326169 1.2571605619956916 1.2627522447055313 0.9152407406458396 0.9485232496357646 1.0031948966711055 0.9557375911734096 1.0 15.208357448644174 -6.760450536376442 24.999999980873568 0.9637379534783133 1.2215918088611128 0.7639573634591341 0.07126631141447791 13.742767798397795 347449.218509892 0.02597416189950226 0.024571016482512066 1.7359989718302862e-07 6.760450536376442 0.2578538553827996 LSQSSQDSS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 3 LSQSSQDSSPVR 12 0 O95251-2;O95251-4;O95251 O95251-2 KAT7 Histone acetyltransferase KAT7 1 LSQS(0.004)S(0.022)QDS(0.229)S(0.744)PVR;LSQSSQDS(0.426)S(0.574)PVR;LSQSSQDS(0.082)S(0.918)PVR 136.33 6.308e-05 150505000.0 126610.0 114287.0 161131.0 188499.0 162680.0 146172.0 132574.0 195041.0 128419.0 135585.0 True False 166869.3463484016 151228.03774590508 158994.2976588748 145043.4678305187 140094.69006120236 137031.84173269535 144372.8291701309 164901.89504630677 135206.9661674155 130838.21041886181 1.275386951672533 1.155840004703273 1.2151977403991914 1.1085711686683926 1.0707475256097367 1.0473380925496107 1.10344545915096 1.2603496678714454 1.033390518981937 1.0 16.9974244061859 -5.789473004196396 5.6019794203820155 1.0973896616512524 1.2100146454007297 0.3944457089476674 0.07119669880655229 0.20317156098618386 17.717136012966346 0.020235057929461977 0.03163175525193377 1.6237792816847407e-06 5.789473004196396 0.11262498374947727 LSQSSQDSS(ph)PVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LSQSSQDSSPVR 12 0 O95251-2;O95251-4;O95251 O95251-2 KAT7 Histone acetyltransferase KAT7 1 LSQS(0.003)S(0.009)QDS(0.443)S(0.544)PVR;LSQSS(0.003)QDS(0.331)S(0.667)PVR;LSQSSQDS(0.036)S(0.963)PVR 144.88 0.0001028 92505000.0 196057.0 209482.0 218955.0 239680.0 246972.0 199854.0 202973.0 189781.0 180673.0 148206.0 True False 229245.57779774148 230277.98854169273 224175.71759146126 226251.50665304463 198579.60950333587 189373.30441714055 183745.92804273582 184799.44983959058 183315.0008252649 175074.57460194992 1.309416734662671 1.3153137116868823 1.280458445214834 1.2923150444172191 1.1342572726783833 1.081672223666402 1.0495294845667973 1.0555470447936324 1.0470680922232736 1.0 17.417610056443138 -6.429413651105667 1.6118109575504527 1.0436271971612088 1.3089403297147566 0.9744882811264228 0.01933994568091192 0.05149984992498744 0.2688121732510415 0.007074478000681721 0.008360504210274414 3.720371843538275e-07 6.429413651105667 0.2653131325535478 LSQSSQDSS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 3 LSQSSQDSSPVR 12 0 O95251-2;O95251-4;O95251 O95251-2 KAT7 Histone acetyltransferase KAT7 1 LSQSSQDS(0.087)S(0.913)PVR;LSQSSQDS(0.226)S(0.774)PVR;LSQSSQDS(0.105)S(0.895)PVR 170.26 6.389899999999999e-05 166767000.0 94787.0 97319.0 107410.0 84747.0 83498.0 88375.0 63387.0 64782.0 81457.0 61595.0 True False 93435.31999819289 97093.66383476138 98579.16441459037 90979.57708770438 78586.81180338403 84595.40726218703 66668.868705027 67792.00821831806 72282.45487976282 72241.61367982162 1.2933725485743275 1.3440129433581767 1.3645758918328994 1.2593790815765875 1.0878330064951849 1.1710066117448321 0.9228596277002712 0.938406615870675 1.0005653417450255 1.0 16.14054249858465 -6.549530973189036 1.0276911048466637 0.9620577014552413 1.3435569134246217 0.8778133666772278 0.05639742745728377 0.16475048983327098 0.37394751296207057 0.029114657514992846 0.03291360357859047 2.821428356149752e-07 6.549530973189036 0.3814992119693804 LSRGS(ph)ISSTSEVHSPPNVGLR ddPTM_PC-9_AZD4547_30min_R2 1 LSRGSISSTSEVHSPPNVGLR 21 1 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 LS(0.114)RGS(0.572)IS(0.031)S(0.032)T(0.029)S(0.207)EVHS(0.015)PPNVGLR 49.485 0.022807 9004800.0 5295.7 2617.2 8837.4 19387.0 9016.0 10229.0 5813.5 12334.0 8202.2 9965.0 True False 6979.622442597179 3463.1587178645213 8720.210301745421 14917.626676164164 7764.28402748833 9589.379012969228 6330.890237758219 10428.063707123885 8635.751546876822 9616.128383109943 0.725824590160048 0.36014064911480564 0.9068317262758119 1.5513131773870585 0.80742308319487 0.9972182806764832 0.6583616592388664 1.0844347425144667 0.8980486951531258 1.0 13.231240441988186 -5.393333620936991 6.130965495452023 0.9981968908561141 0.5487550934350197 0.372362977080156 0.2332001084220325 0.23195267283814222 10.4695879905132 0.061784325070221226 0.13044615944836901 4.042652196449333e-06 5.393333620936991 -0.44944179742109436 LSRGSISSTS(ph)EVHSPPNVGLR ddPTM_PC-9_AZD4547_30min_R2 1 LSRGSISSTSEVHSPPNVGLR 21 1 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 LS(0.051)RGS(0.134)IS(0.065)S(0.073)T(0.073)S(0.603)EVHSPPNVGLR 54.744 0.0086076 6507100.0 2360.7 1443.6 9248.7 17594.0 11208.0 11050.0 6071.4 13213.0 6625.2 11366.0 True False 3111.3534943896325 1910.2154688633736 9126.056195006775 13537.975124590317 9651.962664162504 10359.041753183104 6611.742838139716 11171.234454534451 6975.39454638613 10968.079799541147 0.283673491737341 0.17416133943001474 0.8320559625567793 1.2343067676401007 0.8800047811984644 0.9444717710402215 0.6028168064948178 1.0185223538400772 0.6359722644138629 1.0 13.421023352313094 -5.292240926504913 5.981402626573357 0.899616853351435 0.2267932677392583 0.6986890447808528 0.1747253021305787 0.08812256746569484 10.377959206541371 0.04563573214575501 0.10108039453608493 5.10221873937495e-06 5.292240926504913 -0.6728235856121767 LSS(ph)AGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSSAGPR 7 0 Q6PL18;Q6PL18-2 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 LS(0.126)S(0.874)AGPR 93.162 0.016377000000000003 0.0 18165.0 28068.0 31524.0 27741.0 38419.0 33556.0 40090.0 27712.0 36337.0 29250.0 True False 21239.975724896143 30854.40554505026 32275.65171543576 26186.761707535476 30891.07274309911 31796.26428803808 36292.38497353483 26984.58936329106 36868.359882149845 34552.79345712741 0.6147108120577975 0.8929641414762586 0.9340967396885843 0.7578768338955755 0.8940253349248967 0.9202226826462067 1.0503459009346343 0.7809669396708296 1.0670153175283947 1.0 15.07651473108429 -4.761578300647769 4.776997628039371 0.9148901337235887 0.5929845178196096 0.4797506908195429 0.0959989829546775 0.16326548356525036 9.049176982753883 0.02309109673589916 0.1788202669860537 1.731496824283723e-05 4.761578300647769 -0.32190561590397915 LSS(ph)ATANALYSSNLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LSSATANALYSSNLR 15 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LS(0.009)S(0.985)AT(0.006)ANALYSSNLR;LS(0.309)S(0.687)AT(0.004)ANALYSSNLR;LS(0.02)S(0.971)AT(0.009)ANALYSSNLR 110.6 0.00051001 41036000.0 77084.0 102445.0 78029.0 98898.0 153908.0 175085.0 243582.0 209095.0 178423.0 152327.0 True False 90132.79872160184 112615.0625645816 79889.50728663057 93357.0656916421 123750.8322378225 165903.23438047306 220508.14957903596 203606.47780446516 181032.09883184676 179942.6792801316 0.5008972806350442 0.6258385337769949 0.4439719782223538 0.5188155809679007 0.6877236280625197 0.9219782379820955 1.2254355134712247 1.1315074256924573 1.0060542588121586 1.0 17.457177883834277 -6.760709369877618 2.1686412134643476 1.1011621402034357 0.5273013274921743 0.9177371218852788 0.07728395023446386 0.07918064356978788 0.7655453716718307 0.030570391274039207 0.028174562951247404 1.7349646487186628e-07 6.760709369877618 -0.5738608127112614 LSS(ph)ATANALYSSNLR ddPTM_PC-9_Lapatinib_30min_R1 1 LSSATANALYSSNLR 15 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LS(0.063)S(0.932)AT(0.005)ANALYSSNLR 77.24 0.013125 13152000.0 18755.0 18126.0 18219.0 17132.0 43881.0 74425.0 94678.0 85766.0 75482.0 78722.0 True False 18487.55026075422 18084.030360658133 16721.104147373786 18391.944430676638 41300.00585336532 71242.01624314867 99579.96357698806 89751.00146417638 66980.42229930224 92328.9928095285 0.20023558904074035 0.195865131963097 0.18110350431168293 0.1992000981600501 0.44731351005383324 0.7716104559931513 1.078534061152579 0.9720782035316856 0.7254538391584161 1.0 16.4944961283364 -6.683484176593597 2.050316130285725 0.9431833023746513 0.1922757039022009 0.9392355757447525 0.08715122803214978 0.07235917230561287 0.6245736842705183 0.034695821552800266 0.03362562200951983 2.0726015729057325e-07 6.683484176593597 -0.7509075984724505 down LSS(ph)ATANALYSSNLRDDTK ddPTM_PC-9_AZD4547_30min_R2 2 LSSATANALYSSNLRDDTK 19 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LS(0.019)S(0.859)AT(0.123)ANALYSSNLRDDTK;LS(0.184)S(0.665)AT(0.15)ANALYSSNLRDDTK 221.81 6.7710000000000005e-28 38253000.0 79190.0 64213.0 99851.0 122343.0 113316.0 76831.0 68991.0 65271.0 67693.0 86121.0 True False 104370.77274567519 84968.5964963452 98526.91049851554 94138.71153050778 97584.0293765381 72026.7454243266 75131.06534672341 55184.86672836738 71271.11378200154 83105.93000319229 1.2558763585422372 1.0224131598440853 1.1855581243688735 1.1327556472431233 1.1742125907596448 0.8666859924623896 0.9040397639956312 0.6640304335231866 0.8575936010735197 1.0 16.342663803367742 -6.793612974612013 5.981755714340689 0.8378306197999659 1.147805444177686 0.7026947537658945 0.09571056762597088 0.09565114089372927 9.604553266155488 0.03272761462944861 0.029521987881526008 1.608373931271751e-07 6.793612974612013 0.30997482437772006 LSS(ph)ATANALYSSNLRDDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LSSATANALYSSNLRDDTK 19 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LS(0.029)S(0.736)AT(0.236)ANALYSSNLRDDTK;LS(0.061)S(0.933)AT(0.007)ANALYSSNLRDDTK;LS(0.06)S(0.793)AT(0.145)ANALY(0.002)S(0.001)SNLRDDTK 124.45 0.00013063 64981800.0 28947.2 16348.0 20968.0 39137.0 79338.0 129173.0 152049.0 171541.0 137582.0 116840.0 True False 33847.38922673899 17970.921399831892 21467.956641582816 36944.28077386598 63792.288432598354 122398.9404839298 137645.817980569 167038.23051271334 139593.8764704276 138022.16709506908 0.24523154460707064 0.1302031534358796 0.15553991864796457 0.26766918351904245 0.46218871776341913 0.8868063953786636 0.997273270501246 1.2102275600241672 1.0113873692062518 1.0 17.07454046455534 -6.696550474810706 1.538242197699975 1.0836787791741105 0.17431384749648612 0.9732533006745271 0.06545481125585721 0.05321437026637285 0.2614893749442398 0.027659229058067097 0.02647320567967933 2.0111734409180738e-07 6.696550474810706 -0.9093649316776243 down LSS(ph)ATANALYSSNLRDDTK ddPTM_PC-9_Lapatinib_30min_R1 1 LSSATANALYSSNLRDDTK 19 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LS(0.019)S(0.685)AT(0.262)ANALY(0.009)S(0.013)S(0.013)NLRDDTK 119.04 0.00025309 11014000.0 6073.8 5516.9 5769.0 7062.4 22967.0 52305.0 45524.0 43688.0 52609.0 46163.0 True False 5987.186498201492 5504.125957007324 5294.695088983993 7581.792455475762 21616.126214859323 50068.037078910245 47881.009969357256 45717.90397088518 46683.620422670225 54142.21304166897 0.11058259649626123 0.10166052785413915 0.09779236554126602 0.1400347719373912 0.39924718626154243 0.924750472249386 0.8843563511618382 0.8444040500468596 0.8622407138537456 1.0 15.724466237900057 -6.586903007440784 2.5946571803674368 0.8977845393052233 0.11110870310753058 0.9833377961065278 0.04875248836021428 0.03423181854107242 0.467753614665949 0.018454543692204353 0.018967944337222035 2.588791014667429e-07 6.586903007440784 -0.7866758361976927 down LSS(ph)DSFAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSSDSFAR 8 0 A0A087WSV0;Q9HB09;Q9HB09-3 A0A087WSV0 BCL2L12 Bcl-2-like protein 12 1 LS(0.013)S(0.95)DS(0.037)FAR 155.58 4.5133e-05 14808000.0 56757.0 74910.0 58256.0 44629.0 76794.0 39567.0 53762.0 53393.0 46420.0 36328.0 True False 66364.83909815186 82346.56973705701 59645.043977110334 42128.58181917019 61746.76697034162 37492.03686627737 48669.274156826665 51991.49032455973 47098.80468198796 42913.97882771025 1.5464620366382578 1.9188752007279386 1.3898744792826474 0.9816983409603373 1.4388497328164485 0.8736555754198246 1.1341123681917866 1.2115280788410137 1.0975166127354172 1.0 15.389160048263133 -5.5016922440436025 4.561970201542378 1.1214176865062493 1.7256066321302572 0.6937786697724253 0.1663746083820484 0.10021643598605752 5.192437657386461 0.042465421582603136 0.08578223521318715 3.149979706980935e-06 5.5016922440436025 0.6041889456240079 LSS(ph)ERPSSDGEGVVENGITTCNGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSSERPSSDGEGVVENGITTCNGK 24 1 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 LS(0.084)S(0.363)ERPS(0.314)S(0.239)DGEGVVENGITTCNGK;LS(0.116)S(0.457)ERPS(0.328)S(0.099)DGEGVVENGITTCNGK 90.29899999999999 6.164400000000001e-06 35334000.0 56937.0 58229.0 64539.0 72010.0 83105.0 74374.0 83176.0 70288.0 72536.0 62465.0 True False 66575.3095429898 64009.59029794535 66077.85452552057 67975.51315957 66821.1718242343 70473.69651205573 75296.96713790823 68443.01447629205 73596.70177537003 73789.41002733204 0.9022339319196332 0.8674630990305495 0.8954923816445333 0.9212096035785008 0.9055658772645471 0.955065184637631 1.0204305348154672 0.9275452188998442 0.9973884023210021 1.0 16.171126160641002 -6.819476415258313 2.8476304694558574 0.9813544947587576 0.8961740078620976 0.7243958593790296 0.0256899283306538 0.1464358093563144 2.418640361361169 0.00964181976738661 0.008655467911062996 1.5153870958858535e-07 6.819476415258313 -0.08518048689666002 LSS(ph)FSCGQASATPFTDIK ddPTM_PC-9_AZD4547_30min_R2 1 LSSFSCGQASATPFTDIK 18 0 Q14680-3;Q14680-4;Q14680-5;Q14680-2;Q14680-8;Q14680-6;Q14680;Q14680-7 Q14680-3 MELK Maternal embryonic leucine zipper kinase 1 LS(0.11)S(0.866)FS(0.024)CGQASATPFTDIK 104.16 0.0003724 5449400.0 20297.0 23578.0 25889.0 32105.0 30073.0 27306.0 20205.0 28943.0 22305.0 27533.0 True False 26751.023796173315 31199.127407079948 25545.694944427913 24703.688267305428 25897.883047765816 25598.551503386207 22003.20585772853 24470.52439397492 23483.99676343999 26569.078050392953 1.0068480263197417 1.1742645848646043 0.9614821747286822 0.9297909479753312 0.9747377383078895 0.9634715760491963 0.8281508984239334 0.921015187187235 0.8838845186460155 1.0 14.697460546587394 -5.426795466893703 5.696350879637457 0.9259972335408554 1.0892938169065662 0.53868313058523 0.05895982219964262 0.15644349421047718 7.4335866734565705 0.015291635300562425 0.03230968864655412 3.7428681897494995e-06 5.426795466893703 0.16329658336571085 LSS(ph)FSCGQASATPFTDIK ddPTM_PC-9_Lapatinib_30min_R1 1 LSSFSCGQASATPFTDIK 18 0 Q14680-3;Q14680-4;Q14680-5;Q14680-2;Q14680-8;Q14680-6;Q14680;Q14680-7 Q14680-3 MELK Maternal embryonic leucine zipper kinase 1 LS(0.031)S(0.926)FS(0.044)CGQASATPFTDIK 140.75 0.00015758 3714600.0 11052.0 9196.0 11745.0 10131.0 16356.0 19045.0 18684.0 16400.0 24464.0 21420.0 True False 10894.396453311429 9174.707227000556 10779.371437011088 10876.067536025277 15393.972237133243 18230.489746063387 19651.366098485887 17162.003871143505 21708.60670265932 25122.418459644083 0.43365237589732325 0.3652000002204619 0.4290737953563967 0.43292279178838905 0.6127583720437453 0.7256661923432377 0.7822242962019467 0.683135021363968 0.8641129331370461 1.0 14.616687734375612 -6.872355862899171 0.37455548341159345 0.9859134705340588 0.2810176090093348 0.9183859080447823 0.05819453224770368 0.439214335742058 0.1320380274916594 0.07014069463531898 0.11673500579375855 1.3416651440020332e-07 6.872355862899171 -0.7048958615247239 down LSS(ph)GFDDIDLPSAVK ddPTM_PC-9_AZD4547_30min_R2 9 LSSGFDDIDLPSAVK 15 0 Q9Y446;Q9Y446-2;E9PKC4 Q9Y446 PKP3 Plakophilin-3 1 LS(0.01)S(0.99)GFDDIDLPSAVK;LS(0.032)S(0.968)GFDDIDLPSAVK;LS(0.118)S(0.882)GFDDIDLPSAVK;LS(0.304)S(0.696)GFDDIDLPSAVK;LS(0.072)S(0.928)GFDDIDLPSAVK;LS(0.059)S(0.941)GFDDIDLPSAVK;LS(0.116)S(0.884)GFDDIDLPSAVK;LS(0.254)S(0.746)GFDDIDLPSAVK;LS(0.338)S(0.662)GFDDIDLPSAVK 222.88 1.3294999999999998e-77 85005230.0 285930.69999999995 324644.6 368003.8 476026.2 482177.3 444462.1 392335.47 525638.66 397795.53 418368.0 True False 376850.7148719765 429579.61817883275 363123.8291625885 366285.714121476 415235.3048810384 416669.81462510704 427252.5667754856 444413.28307177057 418822.18960013037 403721.06366130855 0.933443282484081 1.064050545896752 0.8994423671369843 0.9072742224536543 1.0285202885262124 1.0320735084921442 1.0582865379893038 1.1007929064721769 1.0374048502742739 1.0 18.62299933409883 -6.435667248873461 5.259533950784034 1.0507354495736088 0.9556808587707957 0.46280963649255347 0.0484314474658517 0.21231405276718504 9.637386569708747 0.01580248437433467 0.017812260802210548 3.667184422259107e-07 6.435667248873461 -0.09505459080281309 LSS(ph)GFDDIDLPSAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 LSSGFDDIDLPSAVK 15 0 Q9Y446;Q9Y446-2;E9PKC4 Q9Y446 PKP3 Plakophilin-3 1 LS(0.069)S(0.931)GFDDIDLPSAVK;LS(0.119)S(0.881)GFDDIDLPSAVK;LS(0.1)S(0.9)GFDDIDLPSAVK;LS(0.398)S(0.602)GFDDIDLPSAVK;LS(0.118)S(0.882)GFDDIDLPSAVK;LS(0.12)S(0.88)GFDDIDLPSAVK;LS(0.139)S(0.861)GFDDIDLPSAVK 226.93 5.209999999999999e-92 75288700.0 116345.33 87712.98 93962.64 106047.7 129381.35 96799.43 88833.59 110091.27000000002 83156.43 77776.33 True False 136040.29644398746 96420.5449795099 96203.0656928966 100106.19118028237 104030.00323929235 91723.09748514241 80418.6292557034 107201.49081384252 84372.43547224045 91876.56295191067 1.4806855205847507 1.049457466426749 1.047090385207928 1.0895726610134424 1.13228009295192 0.9983296559880175 0.8752899180370461 1.1667990983723793 0.918323811442555 1.0 16.48740926690327 -4.761107708387699 6.095366061712155 1.034650479316889 1.4964504724575751 0.717901412358023 0.08462500681832706 0.0698987229613615 10.383835672152953 0.02072396547123961 0.13474026967595548 1.733374054280877e-05 4.761107708387699 0.4617999931406862 LSS(ph)GFDDIDLPSAVK ddPTM_PC-9_Lapatinib_30min_R1 7 LSSGFDDIDLPSAVK 15 0 Q9Y446;Q9Y446-2;E9PKC4 Q9Y446 PKP3 Plakophilin-3 1 LS(0.153)S(0.847)GFDDIDLPSAVK;LS(0.013)S(0.987)GFDDIDLPSAVK;LS(0.377)S(0.623)GFDDIDLPSAVK;LS(0.066)S(0.934)GFDDIDLPSAVK;LS(0.281)S(0.719)GFDDIDLPSAVK;LS(0.002)S(0.998)GFDDIDLPSAVK;LS(0.119)S(0.881)GFDDIDLPSAVK 222.88 3.6150000000000006e-24 34760130.0 105166.29 104150.7 102236.51 108833.95 106303.70000000001 105591.4 99487.1 102112.1 119715.1 100967.3 True False 103666.59941946458 103909.54545314975 93831.01879214135 116837.96174241432 100051.12536711541 101075.50196757569 104638.05524388116 106856.6009445482 106231.5247821097 118419.36327452933 0.8754193279956783 0.8774709015472263 0.7923621289418243 0.9866457521102451 0.8448882226732534 0.8535386373700921 0.8836228497640269 0.9023575029433709 0.897079006714765 1.0 16.85354547614778 -9.453367205255603 0.5425027058156441 1.009669601489933 0.870864538503218 0.3994999291341216 0.045801084453146554 3.8591480832872556 1.444688445264275 0.12518718651881736 0.02066550092555573 3.520730598693357e-10 9.453367205255603 -0.1388050629867149 LSS(ph)GLVSPAPSFYSK ddPTM_PC-9_AZD4547_30min_R2 1 LSSGLVSPAPSFYSK 15 0 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 LS(0.001)S(0.57)GLVS(0.374)PAPS(0.055)FYSK 162.46 0.00032066 10658000.0 35814.0 33912.0 47624.0 56174.0 48207.0 48239.0 39090.0 40961.0 46159.0 47892.0 True False 47202.10702252307 44873.39081469573 46992.47464303121 43223.9521796485 41514.29016339062 45222.60770423526 42568.93427263587 34631.41864014118 48598.87050453382 46215.315657190265 1.0213520420947138 0.9709636335181938 1.0168160484200877 0.9352733301719565 0.8982799224250619 0.9785199356784972 0.9211001519149618 0.7493493909470498 1.0515749987520147 1.0 15.496083416494193 -5.845432135559301 5.42607158224824 0.9219596036827695 0.9996257677556746 0.1383888914999173 0.07622044864839676 0.3548427873956632 17.232560466930114 0.021062407283172033 0.03198096709164959 1.4274728748585348e-06 5.845432135559301 0.07766616407290505 LSS(ph)GLVSPAPSFYSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSSGLVSPAPSFYSK 15 0 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 LS(0.002)S(0.575)GLVS(0.421)PAPS(0.002)FYSK 173.44 7.6948e-05 8414800.0 25058.0 32076.0 30943.0 35183.0 40032.0 27296.0 27645.0 23569.0 33119.0 20856.0 True False 29299.82448194042 35260.293297101045 31680.798471981 33211.81057482499 32188.016972116522 25864.549708138275 25026.265467532317 22950.338723419703 33603.30272000774 24637.02770399484 1.189259712412042 1.4311910397934757 1.2859018081488793 1.3480445358041206 1.3064894580159645 1.049824273402282 1.015798892959574 0.9315384550100723 1.363934932563275 1.0 14.588540594374354 -6.7499586033896035 8.732126503741025 1.064265430329761 1.3196586616012387 0.4960358371071465 0.12068819584661594 0.12434318402284573 67.81366396655736 0.03909363171444041 0.037678025935873695 1.778448922320433e-07 6.7499586033896035 0.2553932312714777 LSS(ph)LSSQTEPTSAGDQYDCSR ddPTM_PC-9_AZD4547_30min_R2 2 LSSLSSQTEPTSAGDQYDCSR 21 0 Q9BY89;A0A1B0GVJ7;Q9BY89-2 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 LS(0.061)S(0.935)LS(0.004)SQTEPTSAGDQYDCSR;LS(0.01)S(0.986)LS(0.003)SQTEPTSAGDQYDCSR 431.38 0.0 0.0 17731.5 16552.7 24356.0 31400.0 21483.2 16679.4 16317.3 17917.1 16129.2 16180.3 True False 23369.748161888303 21903.036569309203 24033.023526072317 24161.21512516401 18500.62850702499 15636.434481270795 17769.50808920138 15148.423888998654 16981.75658358557 15613.832621900021 1.4967336161340556 1.4027969365181947 1.5392136004047787 1.5474237306268672 1.184887077697755 1.0014475535839338 1.1380619044345204 0.9701925373371441 1.0876097493044017 1.0 13.930537088930148 -6.416092280085973 3.546062357695611 1.0460615183071202 1.4922874594474076 0.9289412838285402 0.059624863357922636 0.060217160126937744 1.3927598189656263 0.019440036096060646 0.021977522098327523 3.836257229828008e-07 6.416092280085973 0.44622594114028735 LSS(ph)LSSQTEPTSAGDQYDCSR ddPTM_PC-9_Lapatinib_30min_R1 2 LSSLSSQTEPTSAGDQYDCSR 21 0 Q9BY89;A0A1B0GVJ7;Q9BY89-2 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 LS(0.011)S(0.856)LS(0.132)S(0.001)QTEPTSAGDQYDCSR;LS(0.011)S(0.918)LS(0.072)SQTEPTSAGDQYDCSR 399.9 0.0 0.0 2026.79 3550.1800000000003 3862.9 2101.48 8296.3 15960.099999999999 21085.0 19172.2 19100.0 22257.9 True False 1997.8876029322353 3541.959776332411 3545.307273225213 2256.029849531774 7808.3279451533635 15277.523727810249 22176.67813030266 20063.010403557164 16948.75686808342 26105.148358212507 0.07653232134586636 0.13568050745124893 0.13580873874290328 0.08642087831008406 0.2991106519682703 0.5852302970346476 0.8495135835275198 0.7685461169672102 0.6492495899856264 1.0 14.6720467372412 -6.778584711976744 1.8764819777274175 0.8006659895699387 0.11064182747756011 0.933121370981355 0.08626762792823804 0.0786618204168954 0.5714895681114113 0.03460364481042483 0.03129925725530887 1.6650040261928595e-07 6.778584711976744 -0.6900241620923786 down LSS(ph)PER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSSPER 6 0 M0QXB4;O14579-3;O14579;M0R061;O14579-2;Q8TDZ2-3;Q8TDZ2-2;Q8TDZ2;Q8TDZ2-4 M0QXB4;Q8TDZ2-2 COPE;MICAL1 Coatomer subunit epsilon;Protein-methionine sulfoxide oxidase MICAL1 1 LS(0.059)S(0.941)PER 102.77 0.035621 23969000.0 54469.0 49851.0 60495.0 55584.0 56689.0 60952.0 56991.0 46673.0 53289.0 60459.0 True False 63689.52588821187 54799.87782621846 61937.430228565056 52469.80868575937 45581.1973953915 57755.56982013644 51592.39990089106 45447.88320413122 54068.25081211667 71419.73810681935 0.8917636437276522 0.7672931780323347 0.8672312706597716 0.7346681754458774 0.6382156894389296 0.808677983861464 0.7223829331847533 0.636349059921738 0.757049132989667 1.0 16.124035223180993 -5.772632216103274 24.649970331136807 0.7374022549673765 0.8346157429674576 0.10769271573208195 0.10176864545213965 310.1906663376639 683132.7430552273 0.026955870169714683 0.04041146754522296 1.6879818940249366e-06 5.772632216103274 0.097213488000081 LSS(ph)PGPSR ddPTM_PC-9_AZD4547_30min_R2 3 LSSPGPSR 8 0 Q86VQ6;H0YBI6;H0YBQ0 Q86VQ6 TXNRD3 Thioredoxin reductase 3 1 LS(0.135)S(0.865)PGPSR;LS(0.033)S(0.967)PGPSR;LS(0.136)S(0.864)PGPSR 92.23899999999999 0.0081241 212808000.0 199949.0 200984.0 280149.0 364178.0 308052.0 253340.0 229073.0 292202.0 250090.0 260186.0 True False 263528.62280243693 265948.14754366607 276434.0412138953 280222.3885940122 265284.29716457735 237498.6097512582 249460.05322679735 247048.89503397158 263309.246831146 251076.96733445444 1.0495929817863217 1.0592295675986958 1.1009932298794387 1.1160816205842319 1.0565855561382402 0.9459195412173798 0.9935600858779562 0.983956822709599 1.0487192418586018 1.0 17.937770162797484 -6.581140089198421 7.025630972099017 0.9937082820197728 1.081928643597174 0.6695886289487265 0.029233337728315982 0.1315668879014291 12.834818396154354 0.010030967484247552 0.010045996942898807 2.623372192804213e-07 6.581140089198421 0.08822036157740121 LSS(ph)PGPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LSSPGPSR 8 0 Q86VQ6;H0YBI6;H0YBQ0 Q86VQ6 TXNRD3 Thioredoxin reductase 3 1 LS(0.164)S(0.836)PGPSR;LS(0.02)S(0.98)PGPSR;LS(0.167)S(0.832)PGPSR 114.97 0.0036543 134048000.0 166302.0 167560.0 202531.0 199033.0 226633.0 200698.0 182972.0 165273.0 169796.0 152434.0 True False 194453.64398577888 184194.24943453848 207360.1071430952 187881.82628369183 182225.89054860346 190173.04357136312 165639.56755743633 160934.7588712186 172278.94527752782 180069.07753312026 1.0798836016140132 1.0229088300886058 1.1515586683946624 1.0433875091581706 1.0119776979203245 1.056111611036517 0.919866807930807 0.8937390088068715 0.9567380898357766 1.0 17.458190929307406 -7.256106055380297 23.420377275553147 0.9337308888504247 1.0603325796062066 0.6312931745161232 0.04411418801834547 114.12204637069811 501149.6819121664 0.017348865346065938 0.013012312631814696 5.5449028904199404e-08 7.256106055380297 0.12660169075578198 LSS(ph)PGPSR ddPTM_PC-9_Lapatinib_30min_R1 2 LSSPGPSR 8 0 Q86VQ6;H0YBI6;H0YBQ0 Q86VQ6 TXNRD3 Thioredoxin reductase 3 1 LS(0.174)S(0.825)PGPS(0.001)R;LS(0.013)S(0.987)PGPSR 120.31 0.0034216 164296000.0 171321.0 193763.0 183693.0 191637.0 226981.0 170705.0 257930.0 259140.0 208456.0 180645.0 True False 168877.93112357627 193314.35367826343 168590.47061548592 205730.62426229185 213630.42384181567 163404.34508279062 271284.35333881725 271180.5904370806 184977.4901410051 211869.2475556681 0.797085622722118 0.912422901900714 0.7957288401243282 0.9710263600583972 1.0083125621413502 0.771250886893609 1.2804328918359802 1.279943142129811 0.873073805071228 1.0 17.69281467272439 -7.256393557139669 24.99998185681299 1.131691055446502 0.8843169174313995 0.41337647395297894 0.13425823488969035 403.91328210582384 2001230.8566776994 0.052090889374703214 0.039085554981532496 5.541233394602017e-08 7.256393557139669 -0.24737413801510255 LSS(ph)PISK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSSPISK 7 0 A0A494C142;Q99728-3;Q99728-2;Q99728 A0A494C142 BARD1 BRCA1-associated RING domain protein 1 1 LS(0.042)S(0.954)PIS(0.004)K 76.1 0.031751 25060000.0 159350.0 197960.0 192320.0 174120.0 210100.0 173970.0 200160.0 166620.0 163340.0 145690.0 True False 186324.80769403785 217612.1605279376 196905.6381776616 164364.62090465683 168932.41321546922 164846.70694331804 181199.39576709218 162246.40154848323 165728.5384910795 172102.4437185949 1.0826389426445215 1.2644338791827718 1.1441187813673492 0.9550394367055577 0.9815805607716471 0.9578405941339175 1.0528577738464406 0.9427315385118685 0.9629644699413019 1.0 17.392908057089002 -5.693629351621087 5.098885604853412 0.978898184085323 1.1794193786280587 0.7376439834836959 0.05051418458735473 0.09066235355542215 4.434969444928103 0.013200921816709997 0.02302435335595429 2.0247464602161745e-06 5.693629351621087 0.20052119454273565 LSS(ph)PISK ddPTM_PC-9_Lapatinib_30min_R1 1 LSSPISK 7 0 A0A494C142;Q99728-3;Q99728-2;Q99728 A0A494C142 BARD1 BRCA1-associated RING domain protein 1 1 LS(0.001)S(0.994)PIS(0.005)K 87.639 0.017806 7625800.0 69362.0 109300.0 115080.0 109610.0 131050.0 119850.0 119950.0 117410.0 127530.0 108070.0 True False 68372.88516056718 109046.92256537182 105618.56662164656 117671.08504824115 123341.89665421315 114724.2948839955 126160.42408014234 122865.2972262779 113166.22844956437 126749.75550577677 0.5394320871684127 0.860332409559574 0.8332841842589027 0.9283732704547754 0.9731134877699366 0.9051243880211415 0.9953504334325318 0.9693533272391848 0.8928319269571031 1.0 16.9516234387783 -4.366355909800763 1.0876134616250122 0.9490738986462599 1.0101532568211631e-25 0.8707868907792542 0.04618869125815951 1.2208327928479423 0.6472391662300865 0.013874089903458621 1.6569787899778619 4.3017393304059675e-05 4.366355909800763 -0.9490738986462599 LSS(ph)PPGKPEDSSSVDGQSVGTPVGPETGGEK ddPTM_PC-9_AZD4547_30min_R2 1 LSSPPGKPEDSSSVDGQSVGTPVGPETGGEK 31 1 A0A087WUE6;Q3T8J9-2;Q3T8J9-3;Q3T8J9 A0A087WUE6 GON4L GON-4-like protein 1 LS(0.228)S(0.756)PPGKPEDS(0.005)S(0.005)S(0.005)VDGQS(0.001)VGTPVGPETGGEK 73.60300000000001 0.00029622 0.0 9769.0 8910.5 10833.0 14357.0 11486.0 12120.0 9699.0 10846.0 9227.1 11896.0 True False 12875.338792177026 11790.644870675453 10689.347341843542 11047.215463438844 9891.367162791812 11362.134484034314 10562.192210547339 9169.99991628552 9714.825668502 11479.5246608606 1.1215916314092211 1.0271021857617169 0.9311663729674136 0.9623408450965124 0.8616530261498018 0.989773951422699 0.9200896833785372 0.7988135560656622 0.8462742104317843 1.0 13.486775284314184 -1.522887252405287 0.5303991179446346 0.8905961190623227 10.23965556237191 0.5641608843899796 0.059827090865483934 88.54664469466115 0.8617536924072265 0.0314281350830174 935.5363447261417 0.02999941235438275 1.522887252405287 9.349059443309587 LSS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 1 LSSPVK 6 0 P26358;P26358-2;P26358-3 P26358 DNMT1 DNA (cytosine-5)-methyltransferase 1 1 LS(0.009)S(0.991)PVK 84.743 0.04204 34439000.0 261570.0 246080.0 261910.0 235760.0 222660.0 240340.0 265540.0 254220.0 250030.0 247830.0 True False 344743.81900601304 325620.5476433219 258436.9022710458 181409.17445569028 191747.50239136568 225311.50180633733 289172.5455808584 214936.14039444044 263246.0753536385 239153.54713358093 1.4415166454271904 1.3615543300365276 1.0806316919342787 0.7585468692812777 0.8017756988745968 0.9421206773089925 1.2091501424368964 0.8987369954182044 1.1007408357886515 1.0 17.86757766402185 -5.309513312042921 3.180905764224574 0.9559819054050467 1.4198161502013404 0.6598276287536635 0.12534616919482616 0.15288522946800903 3.079915007261539 0.036265217575649156 0.09595133369578616 4.903279929731937e-06 5.309513312042921 0.46383424479629376 LSS(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSSPVK 6 0 P26358;P26358-2;P26358-3 P26358 DNMT1 DNA (cytosine-5)-methyltransferase 1 1 LS(0.005)S(0.995)PVK;LS(0.074)S(0.926)PVK 104.37 0.034816 181613000.0 766330.0 1156700.0 936070.0 902820.0 940640.0 659290.0 883340.0 752840.0 713280.0 550010.0 True False 896054.5332925791 1271529.5316360148 958389.4588652446 852237.9223819308 756328.3444407405 624715.6717862862 799663.6403722181 733078.7476999144 723710.370606816 649722.4591232366 1.3791343068265696 1.957034905876382 1.4750751577197079 1.3116953407028245 1.1640791138132465 0.9615115854688236 1.2307772790420675 1.128295224224144 1.1138761796589607 1.0 19.309464050493375 -5.830854360304509 1.9357462203455549 1.106590644821614 1.6735845521716508 0.6921036467933332 0.15226014308555427 0.17227268347460903 1.3181598671958648 0.0452248660095745 0.08447967849817845 1.4762014911900345e-06 5.830854360304509 0.5669939073500367 LSS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 3 LSSPVK 6 0 P26358;P26358-2;P26358-3 P26358 DNMT1 DNA (cytosine-5)-methyltransferase 1 1 LS(0.012)S(0.988)PVK;LS(0.074)S(0.926)PVK;LS(0.023)S(0.977)PVK 101.33 0.034816 300196000.0 1011950.0 2052990.0 2010690.0 1789560.0 2336560.0 1967680.0 2331900.0 2321140.0 1809610.0 1799180.0 True False 997519.4074310961 2048236.4277903293 1845378.8296878524 1921170.212197158 2199128.134653705 1883526.9132861104 2452634.3719256697 2428988.638138173 1605792.6657619074 2110165.865743344 0.47272085271823017 0.970651862510723 0.8745183777474214 0.9104356408117668 1.0421588986698078 0.8925966171017575 1.162294591028125 1.1510889629913135 0.7609793579881635 1.0 21.008924973128913 -4.540473915018066 2.2322918816755615 0.9849884676008739 3.383061109281869e-10 0.6085034640564995 0.11939406890863809 1.2035048443883818 3.5857652127447897 0.03165955887303342 3.0316188500608625 2.8808860789239254e-05 4.540473915018066 -0.9849884672625677 LSS(ph)PVLHR ddPTM_PC-9_AZD4547_30min_R2 4 LSSPVLHR 8 0 Q16643-3;Q16643;Q16643-2;D6R9W4;D6RCR4 Q16643-3 DBN1 Drebrin 1 LS(0.038)S(0.962)PVLHR;LS(0.141)S(0.859)PVLHR;LS(0.477)S(0.523)PVLHR;LS(0.126)S(0.874)PVLHR 146.79 0.0011897000000000001 653354000.0 163965.0 154786.0 219712.0 320790.0 279217.0 250808.0 186263.0 277903.0 168471.0 228650.0 True False 216102.45931613282 204817.54749479514 216798.47532272962 246836.8216560944 240452.53918624722 235124.9361115249 202840.04616075693 234959.47692564037 177376.03311963665 220645.0330956434 0.9794122998565687 0.9282672019451828 0.9825667601987379 1.118705543437715 1.0897709130937827 1.0656253295745157 0.919304836890806 1.06487544101567 0.8038976931909867 1.0 17.751367745843453 -10.292887414763587 5.418268136276863 0.9999999996566822 1.0007762965814102 0.0 0.09032486148504396 1.920564257436409e-10 1.3352848390853048e-18 0.08844119401249007 0.021450135474298866 5.094629256245365e-11 10.292887414763587 0.000776296924728026 LSS(ph)PVLHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LSSPVLHR 8 0 Q16643-3;Q16643;Q16643-2;D6R9W4;D6RCR4 Q16643-3 DBN1 Drebrin 1 LS(0.131)S(0.869)PVLHR;LS(0.046)S(0.954)PVLHR;LS(0.134)S(0.866)PVLHR;LS(0.152)S(0.848)PVLHR;LS(0.316)S(0.684)PVLHR;LS(0.141)S(0.859)PVLHR 120.31 0.0019390999999999998 607412000.0 188824.0 171696.0 225924.0 255873.0 275790.0 242181.0 250679.0 247081.0 222239.0 184477.0 True False 220788.17375600303 188740.8441806667 231310.8849815407 241537.26536145844 221750.92927508024 229480.6020247154 226932.87036120554 240595.3855539598 225488.82494011894 217921.2197808713 1.0131559192721782 0.8660966764524048 1.0614426865549544 1.1083696466288784 1.0175738255230944 1.0530438580302897 1.0413527906524929 1.1040475351408563 1.0347263344380009 1.0 17.73344715818802 -5.2851156613096215 24.712528858348794 1.056644927584814 0.9396262990892625 0.48862480322247603 0.046066393893672036 430.4556097368288 449294.92342487344 0.01124624596363583 0.023433071081715506 5.186618904954321e-06 5.2851156613096215 -0.11701862849555145 LSS(ph)PVLHR ddPTM_PC-9_Lapatinib_30min_R1 4 LSSPVLHR 8 0 Q16643-3;Q16643;Q16643-2;D6R9W4;D6RCR4 Q16643-3 DBN1 Drebrin 1 LS(0.141)S(0.859)PVLHR;LS(0.134)S(0.866)PVLHR;LS(0.134)S(0.866)PVLHR;LS(0.092)S(0.908)PVLHR 112.11 0.0021169 1191731000.0 367551.0 307769.0 334130.0 297882.0 332910.0 300703.0 286410.0 292747.0 351416.0 243196.0 True False 362309.65533940186 307056.37978977157 306659.1211790982 319789.2359852213 313328.8883262425 287842.63366292993 301238.90838510735 306349.09434546594 311835.829505466 285232.1045616999 1.2702274728019929 1.076514091082446 1.075121335483339 1.1211544243121698 1.0985049835386425 1.0091522975831964 1.0561185209077506 1.0740344072285106 1.0932704436783038 1.0 18.12177684922431 -4.761095939239176 6.0573735332728145 1.069719168101178 1.2774649797111584 0.743726610047418 0.03576428802810183 0.06852285069118304 9.90232086092142 0.00905555699075988 0.059087405575175125 1.7334210284285153e-05 4.761095939239176 0.2077458116099804 LSS(ph)SLGR ddPTM_PC-9_AZD4547_30min_R2 2 LSSSLGR 7 0 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 LS(0.074)S(0.463)S(0.463)LGR;LS(0.145)S(0.428)S(0.428)LGR 82.241 0.022769 47775000.0 129617.0 120960.0 183254.0 227760.0 190848.0 178742.0 154700.0 184149.0 143276.0 174472.0 True False 170832.50979891588 160057.95449827757 180823.93222396367 175253.45085692196 164352.04947627473 167565.2344839322 168468.0003063893 155693.0033730469 150849.27685624885 168363.78838514345 1.0146630189154753 0.9506673378727633 1.074007266992097 1.0409212844273732 0.9761721986221193 0.9952569735519107 1.0006189687357678 0.9247416256569894 0.8959722176788456 1.0 17.36122235194503 -7.72805527118921 6.368660966502171 0.9326470671497379 1.0077811713957348 0.36945938024237757 0.03991255000405248 0.1721326724150679 20.33848890562025 0.01979708520247303 0.010951646145063458 1.870444080128417e-08 7.72805527118921 0.07513410424599687 LSS(ph)SLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSSSLGR 7 0 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 LS(0.076)S(0.624)S(0.3)LGR;LS(0.069)S(0.465)S(0.465)LGR 113.5 0.0090135 166327000.0 272320.0 245314.0 316650.0 302820.0 369270.0 304460.0 313900.0 287240.0 312870.0 238010.0 True False 318418.3974348318 269667.15269625385 324200.1369018117 285853.9771556863 296914.1943268749 288493.5816288016 284165.119560803 279700.2543559372 317445.13185811177 281159.32891387626 1.1325194104883092 0.9591257517151683 1.1530833358942878 1.0166974656681163 1.056035364267869 1.0260857526700526 1.010690702167124 0.9948105063290075 1.1290577946832077 1.0 18.10102839097408 LSS(ph)SLGR ddPTM_PC-9_Lapatinib_30min_R1 5 LSSSLGR 7 0 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 LS(0.097)S(0.567)S(0.336)LGR;LS(0.086)S(0.614)S(0.3)LGR;LS(0.086)S(0.614)S(0.3)LGR;LS(0.086)S(0.616)S(0.298)LGR;LS(0.074)S(0.463)S(0.463)LGR 110.12 0.0095119 718047000.0 707205.0 585575.0 721730.0 581870.0 674153.0 648635.0 549210.0 532795.0 651097.0 485514.0 True False 697120.1270144879 584219.1370651198 662392.1453583665 624662.6608614185 634500.6459757932 620894.3930920355 577645.4064948319 557550.6007637753 577763.5995046349 569434.4479932605 1.2242324458437728 1.0259638122069397 1.1632456513523155 1.0969878325113405 1.1142645974647865 1.0903702705028202 1.0144194973284593 0.9791304385054944 1.014627059428398 1.0 19.119170246136193 -7.201175917947801 2.281322257401708 0.9961059994725754 1.1201699127519016 0.5983371776949167 0.04775725888659817 0.21297595543917724 2.170601126209819 0.020823262452720332 0.014259727894068137 6.292512429151523e-08 7.201175917947801 0.1240639132793262 LSS(ph)SPGLFGAFSVR ddPTM_PC-9_AZD4547_30min_R2 1 LSSSPGLFGAFSVR 14 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 LS(0.005)S(0.568)S(0.426)PGLFGAFS(0.001)VR 76.357 0.016399 46067000.0 36556.0 34731.0 35356.0 53921.0 37807.0 26641.0 35011.0 42413.0 23106.0 33793.0 True False 48180.04758796429 45957.116548277816 34887.1563388 41490.34652114548 32558.150646323335 24975.134058511383 38126.911174705914 35859.045403781856 24327.335988166073 32609.917355788664 1.4774661052433404 1.4092987739547234 1.0698327124894444 1.2723229583340367 0.998412547051238 0.7658754171628708 1.169181471965243 1.0996361938775792 0.7460103539283478 1.0 14.9930231643787 -5.016473580396819 0.6822096378135782 0.9633842969710674 1.737467375935753 0.607680211021153 0.14430629909350878 1.7249037324279453 0.7510881667668714 0.06797497518239619 0.985920611070213 9.627785802713897e-06 5.016473580396819 0.7740830789646856 LSS(ph)SPGLFGAFSVR ddPTM_PC-9_Lapatinib_30min_R1 1 LSSSPGLFGAFSVR 14 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 LS(0.001)S(0.499)S(0.499)PGLFGAFSVR 217.19 1.7920000000000003e-15 22196000.0 41382.0 42915.0 45923.0 39193.0 48047.0 44501.0 45294.0 35644.0 36289.0 42820.0 True False 40791.88509147061 42815.63295418975 42147.38820790639 42075.38396401529 45220.969924036486 42597.79596689768 47639.1016947559 37300.150364819456 32201.750679888966 50221.37994593647 0.8122414225850276 0.8525379629209903 0.8392319815440802 0.8377982446780559 0.9004326438802968 0.8482004280398983 0.9485820928465047 0.7427145650910674 0.6411960546395636 1.0 15.616014050010865 -10.591120487741746 4.671891956779934 1.000006946581346 0.8305383561291639 0.30046349063188826 0.07977597070754285 6.532839040474867e-06 1.3030196166694464e-06 0.08079738487557415 0.01959537536797983 2.5637726619890512e-11 10.591120487741746 -0.169468590452182 LSS(ph)SSATLLNSPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSSSSATLLNSPDR 14 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40 Q14244-5 MAP7 Ensconsin 1 LSS(0.5)S(0.5)SATLLNSPDR 275.76 1.249e-69 30007000.0 34550.0 46322.0 66748.0 66913.0 78040.0 71412.0 70554.0 55075.0 68399.0 52947.0 True False 40398.63260639484 50920.54202856698 68339.52546319975 63164.081544873 62748.622214827425 67667.02900635877 63870.614353274555 53629.33960678608 69399.2059768051 62545.87197177864 0.6459040594177524 0.8141311396464802 1.0926304695861506 1.009884098719949 1.0032416246933173 1.0818784177617806 1.0211803327659044 0.8574401142090434 1.1095729228640183 1.0 15.932627049194416 -5.01719849486607 3.2894867134970998 1.0173489897483825 0.6564988287331499 0.7630474699606944 0.06794733949088619 0.11305340101810138 2.427304079801775 0.017535747318125815 0.07732427395071481 9.611728726459735e-06 5.01719849486607 -0.3608501610152326 LSS(ph)SSSNDSGNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSSSSSNDSGNK 12 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 LS(0.073)S(0.687)S(0.206)S(0.03)S(0.004)NDSGNK;LS(0.099)S(0.799)S(0.099)S(0.002)SNDSGNK 131.32 0.00089372 0.0 14016.3 27743.0 25553.0 18681.6 58683.0 42232.0 18934.9 25771.0 31047.0 42575.0 True False 16388.982755456196 30497.141692900434 26162.28043029214 17634.93051856438 47184.48740944027 40017.279574812965 17141.24919519542 25094.538556631574 31501.00363984662 50293.51047648547 0.3258667490136486 0.6063832372003393 0.5201919727302434 0.35064027846712986 0.93818242080161 0.7956748136227811 0.3408242740027015 0.49896176104796713 0.6263433063511205 1.0 15.618084636292066 -14.522878745280336 0.3499659074507316 6.0462847961247395 0.5472851804233305 0.33632718359167224 0.1883381690892994 558.1009937960152 4.577913994524538 2113.507406257052 0.15196632275130356 3.0000000000000132e-15 14.522878745280336 -5.498999615701409 LSS(ph)TDDGYIDLQFK ddPTM_PC-9_AZD4547_30min_R2 5 LSSTDDGYIDLQFK 14 0 Q5JWB9;A0A087WTT2;Q96A57;Q96A57-2 Q5JWB9 TMEM230 Transmembrane protein 230 1 LS(0.034)S(0.914)T(0.052)DDGYIDLQFK;LS(0.035)S(0.937)T(0.027)DDGYIDLQFK;LS(0.027)S(0.936)T(0.038)DDGYIDLQFK;LS(0.256)S(0.707)T(0.037)DDGYIDLQFK;LS(0.006)S(0.82)T(0.174)DDGYIDLQFK 173.33 2.2847e-19 13049500.0 123137.9 136111.4 179859.0 209190.0 172994.0 134023.9 200578.0 245355.0 217833.0 161608.0 True False 162293.1907725681 180106.7482465021 177473.95214221702 160964.4774532823 148976.769193802 125643.36434610264 218429.0534289273 207441.02244700678 229347.20766511653 155950.15310964666 1.0406734942957172 1.154899464060617 1.1380171715345302 1.0321533787793726 0.9552845330588309 0.8056636164875344 1.4006337863314084 1.330175176558868 1.4706443250739567 1.0 17.250725443567084 -7.2810000256988845 24.925795600558445 1.3278779405306458 1.030019512325068 0.4589687145471537 0.14713339906134032 706.2554186541697 899965.4033091187 0.061814372998237485 0.04174305775388477 5.236004056022878e-08 7.2810000256988845 -0.29785842820557784 LSS(ph)TDDGYIDLQFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSSTDDGYIDLQFK 14 0 Q5JWB9;A0A087WTT2;Q96A57;Q96A57-2 Q5JWB9 TMEM230 Transmembrane protein 230 1 LS(0.08)S(0.738)T(0.181)DDGYIDLQFK;LSS(0.988)T(0.012)DDGYIDLQFK 238.88 3.967800000000001e-27 5740900.0 114144.0 103157.0 79841.0 85747.0 142112.0 93711.0 114169.0 122635.0 105561.0 94463.0 True False 133466.32475323667 113397.74521913714 81744.71223867883 80942.8735855248 114266.17375952777 88796.6301912128 103354.0858080194 119415.96119252339 107104.62992320838 111588.39413130321 1.1960591940788237 1.016214509599492 0.7325556826500426 0.7253700012053349 1.023996936680294 0.7957514836778462 0.9262082012436283 1.0701467847275379 0.9598187226996125 1.0 16.767827460386094 -7.6090464602520225 7.3446270507808515 1.0102653398801535 0.9038644037574649 0.08439480792914333 0.13841476518467802 0.5849310864648752 42.41693932779562 0.06967868099202829 0.039955871918014495 2.4601044113381204e-08 7.6090464602520225 -0.10640093612268864 LSS(ph)TDDGYIDLQFK ddPTM_PC-9_Lapatinib_30min_R1 5 LSSTDDGYIDLQFK 14 0 Q5JWB9;A0A087WTT2;Q96A57;Q96A57-2 Q5JWB9 TMEM230 Transmembrane protein 230 1 LS(0.001)S(0.985)T(0.014)DDGYIDLQFK;LS(0.093)S(0.876)T(0.031)DDGYIDLQFK;LS(0.004)S(0.85)T(0.146)DDGYIDLQFK;LS(0.144)S(0.712)T(0.144)DDGYIDLQFK;LS(0.122)S(0.787)T(0.09)DDGY(0.001)IDLQFK 263.83 2.8574999999999998e-56 11449900.0 104058.1 116021.0 64690.4 48578.600000000006 87121.5 75118.0 91565.4 78539.3 105687.7 49472.4 True False 102574.21241208147 115752.36050280878 59371.80502416539 52151.23229745906 81997.18465745925 71905.3782486107 96306.20837905697 82188.52259981117 93784.03828518008 58023.638422170676 1.767800420679723 1.9949173069881139 1.023234782213857 0.8987928664179082 1.413168613468547 1.239242836263364 1.6597754121923287 1.4164661995482026 1.6163074366833476 1.0 15.824353143355665 -5.251291833240725 24.90072575056473 1.3010146538179044 1.8813589248034461 0.4815956645991354 0.24762616217157912 606.3772559003495 1487961.2094776246 0.06712820148946343 0.17320548396290925 5.606710947768484e-06 5.251291833240725 0.5803442709855418 LSS(ph)TDDGYIDLQFKK ddPTM_PC-9_AZD4547_30min_R2 2 LSSTDDGYIDLQFKK 15 1 Q5JWB9;A0A087WTT2;Q96A57;Q96A57-2 Q5JWB9 TMEM230 Transmembrane protein 230 1 LS(0.197)S(0.74)T(0.063)DDGYIDLQFKK;LS(0.019)S(0.883)T(0.098)DDGYIDLQFKK 66.289 0.014749000000000002 14302000.0 26122.0 14176.8 28755.0 41049.0 32902.0 21901.1 28688.0 30957.0 30611.0 29645.0 True False 34428.25262864656 18759.173357565993 28373.689911816768 31585.787250727964 28334.12522986037 20531.620754808908 31241.176423980018 26173.306971090824 32229.034966404906 28607.13757323575 1.2034847086853222 0.6557514994130937 0.9918395309275057 1.104122604712433 0.9904564955974202 0.7177097219967185 1.092076281452522 0.9149222603654702 1.1266081719604737 1.0 14.80408752853893 -8.253003458233074 24.645798912745708 1.0633040884204152 0.9521015143666508 0.0615218136944643 0.16158806745475507 1300.041074035537 3798145.693931899 0.1092595402592597 0.0397211877635531 5.584657477256679e-09 8.253003458233074 -0.11120257405376444 LSS(ph)TDDGYIDLQFKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSSTDDGYIDLQFKK 15 1 Q5JWB9;A0A087WTT2;Q96A57;Q96A57-2 Q5JWB9 TMEM230 Transmembrane protein 230 1 LS(0.178)S(0.642)T(0.178)DDGY(0.003)IDLQFKK 50.966 0.043601 3510000.0 15383.0 11095.0 7957.1 11388.0 20550.0 16137.0 20296.0 18017.0 15656.0 14756.0 True False 17987.038071900766 12196.438275699458 8146.827441469791 10749.967280394148 16523.375019409315 15290.747312435054 18373.41594968478 17544.072840589466 15884.939381757928 17431.14599156828 1.031890736306229 0.6996922796469646 0.4673718782121692 0.6167103003780748 0.9479224732213208 0.8772083786018102 1.0540566844298298 1.0064784523677222 0.9112963306854136 1.0 14.089379800533617 -6.277363059716799 17.87438469487113 0.966432922495172 0.6867188820958469 0.4578024663874498 0.1393119710021445 18.141543592097452 20363.303101640242 0.04569148840089118 0.052257352028904504 5.280036688866186e-07 6.277363059716799 -0.2797140403993251 LSS(ph)TDSLESLLSK ddPTM_PC-9_AZD4547_30min_R2 1 LSSTDSLESLLSK 13 0 Q9Y450-2 Q9Y450-2 HBS1L HBS1-like protein 1 LS(0.007)S(0.948)T(0.045)DSLESLLSK 90.861 0.0054006 7378100.0 53427.0 46458.0 62166.0 95347.0 63258.0 67586.0 62933.0 70171.0 58634.0 54908.0 True False 70415.6746493645 61474.63996429384 61341.63822145721 73366.22224646539 54475.71861256176 63359.83673580387 68533.9150826246 59327.68431916566 61733.273536316585 52985.6876326945 1.3289565125114076 1.1602121763606459 1.157702031663485 1.384642259529632 1.028121386103289 1.195791534782462 1.2934420245276985 1.1196926371973301 1.1650933732192321 1.0 15.693315094511519 -14.522878741956289 0.14962172163977844 0.2656903121311047 1.2649462530401758 0.32252058228569425 0.0964411500342987 169.18602914085417 1.4998204149905874 36.716986103004835 0.48422287020133276 3.0000000229617154e-15 14.522878741956289 0.9992559409090711 LSS(ph)TDSLESLLSK ddPTM_PC-9_Lapatinib_30min_R1 1 LSSTDSLESLLSK 13 0 Q9Y450-2 Q9Y450-2 HBS1L HBS1-like protein 1 LS(0.026)S(0.544)T(0.43)DSLESLLSK 134.06 4.4916e-05 2601900.0 26115.0 20721.0 26050.0 21611.0 38768.0 57122.0 57968.0 60543.0 69559.0 60972.0 True False 25742.595311095545 20673.02179759445 23908.26955590795 23200.345032182642 36487.74246082055 54679.025217885675 60969.299400397664 63356.04880308788 61724.53293125732 71510.92895991686 0.35998127398854973 0.28908898399546795 0.3343302891409642 0.32443076001972854 0.5102400848585337 0.7646247365704651 0.8525871539799468 0.8859631628978007 0.8631482464149643 1.0 16.125876124256862 -6.715324707791886 1.5528570650862483 0.8999542521717181 0.3156832568107626 0.9774315402595509 0.03995539236502773 0.048874686672420085 0.24479695934808332 0.0165111151985744 0.015564734362661573 1.92608430441775e-07 6.715324707791886 -0.5842709953609555 down LSS(ph)TPPLSALGR ddPTM_PC-9_AZD4547_30min_R2 1 LSSTPPLSALGR 12 0 Q8N201 Q8N201 INTS1 Integrator complex subunit 1 1 LS(0.002)S(0.602)T(0.392)PPLS(0.005)ALGR 124.21 0.0003292 7160400.0 54901.0 54339.0 78045.0 109330.0 69791.0 68548.0 62316.0 88521.0 47565.0 66683.0 True False 72358.37598825987 71903.0190929392 77010.07230630296 84125.6576316618 60101.7243303503 64261.68272372799 67862.00327791183 74842.11346021692 50079.188794127935 64348.44846672562 1.1244773994150947 1.117400975566956 1.1967665754384835 1.3073455481240221 0.9340042497128538 0.9986516264950429 1.0546020128675373 1.1630756489632774 0.7782501363653503 1.0 15.973617742970626 -6.273128522825124 24.93867683109251 1.000104014034893 1.1822956501804427 0.4675427614810088 0.10320920629116315 715.9167866058359 1527398.8286555826 0.03205864366930392 0.03665862858711297 5.331770865150605e-07 6.273128522825124 0.18219163614554978 LSS(ph)TPPLSALGR ddPTM_PC-9_Lapatinib_30min_R1 1 LSSTPPLSALGR 12 0 Q8N201 Q8N201 INTS1 Integrator complex subunit 1 1 LSS(0.608)T(0.391)PPLS(0.001)ALGR 114.76 0.00075376 11901000.0 76081.0 71464.0 70212.0 52796.0 59616.0 70854.0 64699.0 59633.0 64054.0 36593.0 True False 74996.07098845331 71298.52949873514 64439.44038615778 56678.79396229304 56109.50408956562 67823.73958874107 68048.79764536166 62403.76688096952 56839.56400147727 42918.051292892436 1.7474248883446684 1.6612713613710306 1.501453081976941 1.3206283196664965 1.307363740880234 1.5803079950177796 1.5855518970552855 1.454021443217392 1.3243742968099381 1.0 15.389296951126054 -12.865309469322668 0.13235909245789107 5.253826903647521e-18 1.7206369483868835 0.6389965329125336 0.12407629846398474 66.76331002948879 0.8476951675736308 20.076277016161004 1.1483810376381998 1.3636111090537374e-13 12.865309469322668 1.7206369483868835 LSS(ph)TSLASGHSVR ddPTM_PC-9_AZD4547_30min_R2 1 LSSTSLASGHSVR 13 0 Q9BZL6-2;Q9BZL6;Q9BZL6-3;M0QZ82 Q9BZL6-2 PRKD2 Serine/threonine-protein kinase D2 1 LS(0.097)S(0.455)T(0.097)S(0.35)LAS(0.001)GHSVR 79.337 0.007928300000000001 2942200.0 2286.4 5990.3 9283.2 15922.0 14795.0 11716.0 5583.9 13999.0 6776.0 9160.7 True False 3013.427639925638 7926.547328298889 9160.098702464878 12251.428892447817 12740.96963028946 10983.396667899833 6080.856282552356 11835.776215017611 7134.165526521829 8839.98668130007 0.34088599322215973 0.8966696007660903 1.03621182165828 1.3859103338203262 1.441288328775591 1.242467558365658 0.6878807063607547 1.3388907293327459 0.8070335152894855 1.0 13.10982848065472 -4.737311457838215 1.8687531178980763 1.1410136782725877 0.02859396983840771 0.5028833589197896 0.23333630541142922 0.7908093732696162 2.6527713091761527 0.06509583701972226 1.6135950079714676 1.8310008341849115e-05 4.737311457838215 -1.11241970843418 LSS(ph)TSSEETQLFHIPR ddPTM_PC-9_AZD4547_30min_R2 2 LSSTSSEETQLFHIPR 16 0 Q8N271-3;Q8N271-2;Q8N271 Q8N271-3 PROM2 Prominin-2 1 LS(0.074)S(0.385)T(0.385)S(0.156)S(0.001)EETQLFHIPR;LS(0.369)S(0.628)T(0.003)SSEETQLFHIPR 279.12 9.244899999999995e-193 2905200.0 13177.7 13419.0 15386.0 23732.7 19757.7 16244.3 12119.8 16810.5 12168.400000000001 13427.0 True False 17367.93448681248 17756.429327152688 15181.971586966192 18261.492681559866 17014.684397726945 15228.541353052695 13198.438720836337 14212.823491860383 12811.596781719041 12956.924816860726 1.340436464076086 1.3704200323865745 1.171726455278187 1.4094002195487276 1.313173043621114 1.1753206542678967 1.0186397549873354 1.0969287614731982 0.9887837556213516 1.0 13.661435730649574 -6.993292760116717 2.5016205944802277 1.032919138257231 1.3215415471220664 0.8248502607044311 0.06396913420364793 0.11931999142823001 1.5031527704831236 0.026290203518178217 0.021039214548965117 1.0155638653125034e-07 6.993292760116717 0.2886224088648355 LSS(ph)TSSEETQLFHIPR ddPTM_PC-9_Lapatinib_30min_R1 1 LSSTSSEETQLFHIPR 16 0 Q8N271-3;Q8N271-2;Q8N271 Q8N271-3 PROM2 Prominin-2 1 LS(0.142)S(0.612)T(0.142)S(0.102)S(0.002)EETQLFHIPR 126.43 1.5969000000000002e-05 2427500.0 17487.0 16752.0 16744.0 12920.0 14675.0 17133.0 13553.0 14701.0 18376.0 11678.0 True False 17237.63217327695 16713.21177323982 15367.37295370912 13870.179899856543 13811.84535216008 16400.26152897369 14254.708024661702 15384.062128639056 16306.301372141425 13696.526740043113 1.2585403949806542 1.2202518266457392 1.1219905049928554 1.0126786274439736 1.008419551489636 1.1974029504155932 1.04075349139331 1.1232090018604695 1.1905428056054812 1.0 13.741522470530475 -5.267641710014145 3.112346532174211 1.086046280612551 1.2489358624735531 0.4570777625941215 0.06785464518256744 0.23136103957128598 4.559175088044602 0.01847571813327951 0.053031299164560376 5.399558987491289e-06 5.267641710014145 0.1628895818610021 LSS(ph)YTECYK ddPTM_PC-9_AZD4547_30min_R2 2 LSSYTECYK 9 0 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1;Q8IWC1-3 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 1 LS(0.225)S(0.774)YT(0.001)ECYK;LS(0.014)S(0.986)YTECYK 97.59700000000001 0.004732500000000001 19433000.0 109502.0 106051.0 158494.0 163672.0 138467.0 126903.0 124880.0 110315.0 103101.0 118770.0 True False 144321.35821690725 140329.91180966306 156392.26600186012 125939.94910719263 119243.24716439963 118967.73534879614 135994.0780753843 93268.35153651459 108550.70837513685 114611.89845077459 1.259217936075745 1.2243921766110022 1.364537784609074 1.098838347584683 1.0404089695417984 1.0380051020609553 1.1865616041059934 0.8137754700623253 0.947115525023425 1.0 16.806397299900382 -6.323875098616201 0.6827604656808633 0.9487656747749825 1.3031655985329709 0.607358471637674 0.09725949115835211 0.5688292866350592 0.5748949386310603 0.06554736166866365 0.11200399170979719 4.743783950033057e-07 6.323875098616201 0.35439992375798834 LSS(ph)YTECYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSSYTECYK 9 0 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1;Q8IWC1-3 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 1 LS(0.011)S(0.989)YTECYK;LS(0.28)S(0.72)YTECYK 117.7 0.0018424 8343900.0 24054.7 24970.0 27762.0 33619.0 63804.0 82263.0 109087.0 115896.0 108770.0 77266.0 True False 28126.68560801869 27448.85657901897 28423.95136797131 31735.436424268573 51302.06422084638 77948.9834642651 98753.4896385132 112853.8528019623 110360.55547737647 91273.71416268064 0.30815756613001877 0.30073123276320085 0.3114144266914592 0.3476952451798476 0.5620683314081943 0.8540134931436408 1.0819488452338104 1.2364332254609312 1.209116518263699 1.0 16.4779118190881 -6.8097379443469 1.3740258951754625 1.1721907388614499 0.3017388579455288 0.9723517781366525 0.06241916665907059 0.05879366903509284 0.23159737184900514 0.029521364046606803 0.02555699197600621 1.5497514653037907e-07 6.8097379443469 -0.8704518809159211 down LSS(ph)YTECYK ddPTM_PC-9_Lapatinib_30min_R1 1 LSSYTECYK 9 0 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1;Q8IWC1-3 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 1 LS(0.081)S(0.919)YTECYK 110.53 0.0022954 6108000.0 15747.0 24769.0 22308.0 18614.0 49537.0 88831.0 111220.0 90518.0 78789.0 95440.0 True False 15522.44489235388 24711.64890230282 20473.922351370235 19982.935654483703 46623.331053489164 85031.905205175 116978.42739636046 94723.79673220532 69914.95313504845 111936.6768341937 0.13867166090115857 0.2207645393913826 0.18290629068519917 0.17852000094735207 0.4165152331844728 0.7596429303607841 1.0450410955976017 0.8462266292978755 0.6245937892064639 1.0 16.772323297320582 -6.660775861359034 2.3457977173815445 0.871753793450169 0.18463345379596086 0.9002661549572673 0.10719911262266124 0.08890876031548027 0.9991494745322228 0.04106787957172325 0.04040201684722246 2.183856705768771e-07 6.660775861359034 -0.6871203396542082 down LSSAGPRS(ph)PYCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LSSAGPRSPYCK 12 1 Q6PL18;Q6PL18-2 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 LS(0.004)S(0.003)AGPRS(0.979)PY(0.014)CK;LS(0.002)S(0.009)AGPRS(0.984)PY(0.005)CK;LS(0.001)S(0.001)AGPRS(0.994)PY(0.004)CK 60.937 0.02732 50337000.0 197613.0 125779.0 174231.0 226142.0 238966.0 199493.0 199987.0 237506.0 200311.0 151499.0 True False 231064.97786533955 138265.50787554783 178385.3278147471 213471.99690225584 192142.32773178408 189031.2358926445 181042.78357950368 231271.71915840777 203240.16942381882 178964.569434576 1.2911213576819733 0.7725859275519532 0.9967633726515871 1.1928170898670236 1.0736333361337507 1.0562494939074998 1.011612433407873 1.292276565630236 1.1356447260256017 1.0 17.449314472202865 -5.727280327192234 21.331471609276377 1.1133529322723947 0.9953987351341447 0.06661369783826565 0.14281558101313593 82.5561341714678 51550.77634740472 0.03765761234709294 0.06521167037963845 1.8737846323516996e-06 5.727280327192234 -0.11795419713825006 LSSAGPRS(ph)PYCK ddPTM_PC-9_Lapatinib_30min_R1 3 LSSAGPRSPYCK 12 1 Q6PL18;Q6PL18-2 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 LSSAGPRS(1)PYCK;LSSAGPRS(0.973)PY(0.027)CK;LSSAGPRS(0.999)PY(0.001)CK 88.09200000000001 0.0038798 51611100.0 188793.0 182149.0 262039.0 225550.0 216734.0 198107.0 171660.0 175801.0 238041.0 174812.0 True False 186100.77719960423 181727.24518170083 240495.1649197918 242137.6994127433 203986.13223543868 189634.4254199727 180547.71486116928 183969.35625310315 211230.31589714385 205028.0212776513 0.9076845986216899 0.8863532118646539 1.1729868113691175 1.1809980796958366 0.9949183090402961 0.9249195511825555 0.8806001917985127 0.8972888442598279 1.0302509607264527 1.0 17.645461571463386 -6.532544287288825 9.500444820163539 0.9385859569470477 1.0424212526423537 0.155976914060717 0.09807767031112054 0.3233483287639244 260.6068397673654 0.035409277334621944 0.03612624753112231 2.9339702963427753e-07 6.532544287288825 0.10383529569530603 LSSAT(ph)ANALYSSNLRDDTK ddPTM_PC-9_AZD4547_30min_R2 1 LSSATANALYSSNLRDDTK 19 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LS(0.006)S(0.307)AT(0.687)ANALYSSNLRDDTK 161.2 5.0491e-05 26209000.0 68016.0 48423.0 71840.0 117890.0 87958.0 66990.0 54277.0 53327.0 50102.0 59780.0 True False 89643.67317931344 64074.7877866245 70887.3546605779 90712.28188234342 75746.5499655964 62801.10471002128 59107.54785151854 45086.53748255193 52750.2894347398 57687.1203956159 1.5539633901734184 1.1107295241503172 1.2288246349347192 1.572487606596452 1.3130582605983738 1.088650365615997 1.0246229564963791 0.781570256468867 0.9144205686291929 1.0 15.815961628827223 -7.02249526711661 1.9138340037427393 0.9001511488958411 1.3494943866475873 0.6721309067575847 0.1412435733515371 0.2120181683796229 1.5557941527531143 0.06634346303431174 0.05028930985537179 9.495213469029204e-08 7.02249526711661 0.4493432377517461 LSSAT(ph)ANALYSSNLRDDTK ddPTM_PC-9_Lapatinib_30min_R1 1 LSSATANALYSSNLRDDTK 19 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 LS(0.025)S(0.108)AT(0.867)ANALYSSNLRDDTK 107.62 0.0020495 16214000.0 10266.0 9654.1 6145.5 7637.5 31391.0 52441.0 57784.0 49926.0 63785.0 56428.0 True False 10119.60495744617 9631.74652459613 5640.240712316023 8199.187227953116 29544.64309708055 50198.22067594169 60775.77278071652 52245.74422382381 56600.86161417285 66181.50461441616 0.15290684333039234 0.1455353210948013 0.08522382114424493 0.1238894049889447 0.44641842564946627 0.758493191842712 0.9183195990300571 0.789431194231919 0.8552368512009263 1.0 16.014140470762932 -6.603396772597903 1.9363434708387532 0.8746152985514386 0.11914891027891313 0.974680623646334 0.056407635092267636 0.04757056215983308 0.36387920693081705 0.021677934324164188 0.02221646295445904 2.4923166993062624e-07 6.603396772597903 -0.7554663882725254 down LSSEMNTS(ph)TVNSAR ddPTM_PC-9_AZD4547_30min_R2 1 LSSEMNTSTVNSAR 14 0 P20700;E9PBF6;A0A0D9SFE5 P20700 LMNB1 Lamin-B1 1 LS(0.002)S(0.001)EMNT(0.03)S(0.744)T(0.223)VNSAR 84.31 0.0064607 5560600.0 17544.0 20696.0 25389.0 36996.0 30912.0 29731.0 25635.0 34915.0 30740.0 31567.0 True False 23122.62706213058 27385.577267661658 25052.325271122092 28467.14378250215 26620.402379959993 27871.915870034987 27916.465338424692 29519.68901688263 32364.85364304619 30461.848938246996 0.7590684041866709 0.8990123128500298 0.8224164370950948 0.9345179224088281 0.8738931912480271 0.9149778113120322 0.9164402789540987 0.9690708228750547 1.0624717399346641 1.0 14.894715891075416 -6.690600568637025 0.37115316572865614 1.0324059372324534 0.7898599234651869 0.690961277899034 0.04554107685970155 1.0194006882177786 0.2824728661669316 0.04930345874525159 0.09539167917655736 2.0389164574482672e-07 6.690600568637025 -0.2425460137672666 LSSEMNTS(ph)TVNSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSSEMNTSTVNSAR 14 0 P20700;E9PBF6;A0A0D9SFE5 P20700 LMNB1 Lamin-B1 1 LSSEMNT(0.01)S(0.954)T(0.036)VNSAR;LS(0.003)S(0.003)EMNT(0.068)S(0.762)T(0.16)VNS(0.004)AR 111.88 0.00031496 14702600.0 49383.0 47106.0 65037.0 60601.0 63885.0 53754.0 62509.0 50319.0 47372.0 42339.0 True False 57742.56654129078 51782.37236729149 66587.72873419612 57205.72244109286 51367.192852309745 50935.045611491245 56587.69499403069 48998.17956738756 48064.725880980855 50014.72554466041 1.1545113146673138 1.0353425276932224 1.3313624739325407 1.1437775938610577 1.0270413821713698 1.0184009820469582 1.1314206841643262 0.9796750663689011 0.9610114892675296 1.0 15.610065301286934 -6.224382367312834 4.7346103880010695 1.0236246869708177 1.1707664955690924 0.4529306265139198 0.07919101170507262 0.20510379750710955 11.339497094782645 0.024626455768883483 0.031309427450097474 5.965098681832924e-07 6.224382367312834 0.14714180859827475 LSSEMNTS(ph)TVNSAR ddPTM_PC-9_Lapatinib_30min_R1 1 LSSEMNTSTVNSAR 14 0 P20700;E9PBF6;A0A0D9SFE5 P20700 LMNB1 Lamin-B1 1 LS(0.002)S(0.013)EMNT(0.042)S(0.867)T(0.076)VNSAR 90.476 0.0043295 4827100.0 48480.0 41188.0 44738.0 42540.0 32889.0 41488.0 29394.0 27798.0 34580.0 26240.0 True False 47788.666309856846 41092.63171658319 41059.81433367408 45668.53350927994 30954.533682261837 39713.65495325162 30915.877494053413 29089.59656158823 30685.23625645678 30775.549037397777 1.5528127947217156 1.3352363483962 1.3341700024190988 1.4839226248664008 1.0058158067187222 1.2904288045354595 1.0045597385276575 0.945217793717967 0.9970654372134433 1.0 14.909496974243439 -6.517354176998169 0.6829349602854409 0.9583057132710452 1.4715695173256154 0.7257207658690997 0.11369597456463858 0.3997012030500296 0.41423853997220955 0.07687921951750852 0.10404641103746874 3.0384061259187946e-07 6.517354176998169 0.5132638040545702 LSSERPS(ph)SDGEGVVENGITTCNGK ddPTM_PC-9_AZD4547_30min_R2 1 LSSERPSSDGEGVVENGITTCNGK 24 1 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 LS(0.118)S(0.149)ERPS(0.366)S(0.366)DGEGVVENGITTCNGK 80.702 5.6408e-05 22911000.0 23679.0 23047.0 26973.0 35056.0 33593.0 31658.0 29661.0 38514.0 28196.0 30032.0 True False 31208.429446203285 30496.492041350928 26615.320396154893 26974.380809800936 28929.191807388564 29678.420255409088 32300.771539029243 32562.54626367516 29686.382996725148 28980.588821029363 1.076873545907988 1.0523075369407806 0.9183843903420573 0.9307740769651771 0.9982265020922038 1.0240792703933383 1.1145657439365289 1.1235985046669101 1.0243540315917816 1.0 14.82279928709264 -7.0191509979803035 4.107327520473972 1.0759098948159243 0.991535944383232 0.24367671046910055 0.05686290314193165 0.2840104431158753 10.996834412036607 0.023431657537382373 0.01896075510965097 9.568613264542111e-08 7.0191509979803035 -0.08437395043269225 LSSERPS(ph)SDGEGVVENGITTCNGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSSERPSSDGEGVVENGITTCNGK 24 1 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 LS(0.155)S(0.155)ERPS(0.534)S(0.155)DGEGVVENGITTCNGK 68.461 0.0034351 0.0 6943.1 5418.4 7591.2 10310.0 10624.0 8625.0 8144.0 9987.8 9293.4 6051.3 True False 8118.429697524162 5956.30294304191 7772.202997786314 9732.364125470991 8542.303465022129 8172.68981655526 7372.541362545965 9725.630832948853 9429.29839361453 7148.352787935561 1.135706356186816 0.8332413242243023 1.0872718832377215 1.3614834653791186 1.195003061326124 1.1432969327351186 1.0313622706183125 1.3605415291426333 1.3190868824393465 1.0 12.803395121174338 -5.524700642031436 24.928693402703985 1.2081262310097212 0.978419513612396 0.2947986289755371 0.13557804739371201 59.22951649708099 810423.3902876666 0.03636753072718104 0.06356664533221366 2.9874411441721575e-06 5.524700642031436 -0.22970671739732518 LSSERPS(ph)SDGEGVVENGITTCNGK ddPTM_PC-9_Lapatinib_30min_R1 1 LSSERPSSDGEGVVENGITTCNGK 24 1 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 LS(0.178)S(0.178)ERPS(0.583)S(0.061)DGEGVVENGITTCNGK 85.881 9.818e-06 32365000.0 75848.0 78402.0 98644.0 100220.0 102180.0 86449.0 78247.0 68882.0 101870.0 75740.0 True False 74766.39361118038 78220.46498600434 90533.87109685178 107590.51312411913 96169.97329360928 82751.77779246177 82298.2467944886 72082.5091861042 90396.32786134334 88831.55808279364 0.8416647779778431 0.880548159620262 1.0191633812442145 1.2111744457284155 1.0826104525148148 0.9315583288017381 0.9264528121614641 0.8114515915494939 1.0176150211965356 1.0 16.438784675509773 -6.894127766002293 9.817404474783986 0.9240194277499496 1.01194944327527 0.08620634742392752 0.10872545931695113 0.7316245817398763 62.557980781781914 0.04251617187440208 0.03750233291452614 1.2760633458393504e-07 6.894127766002293 0.08793001552532043 LSSERPSS(ph)DGEGVVENGITTCNGK ddPTM_PC-9_AZD4547_30min_R2 3 LSSERPSSDGEGVVENGITTCNGK 24 1 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 LS(0.009)S(0.034)ERPS(0.354)S(0.603)DGEGVVENGITTCNGK;LS(0.142)S(0.124)ERPS(0.083)S(0.651)DGEGVVENGITTCNGK;LS(0.033)S(0.029)ERPS(0.188)S(0.75)DGEGVVENGITTCNGK 145.28 1.7359e-06 90952000.0 92976.0 81622.0 123646.0 129734.0 125460.0 116210.0 115435.0 125430.0 110921.0 116395.0 True False 122540.43397906165 108004.71529479511 122006.37325113888 99825.83067031942 108042.04459723683 108943.37032917733 125708.49137277392 106047.6755946609 116784.05761029031 112320.04647788052 1.0909934408119557 0.9615800445387526 1.0862386286063896 0.8887623696806285 0.9619123921793767 0.9699370125406049 1.1191990683295348 0.9441562652446476 1.0397436724110412 1.0 16.777255912177267 -10.119884062267472 15.256100697274814 0.9999961150347308 1.0035104723924047 0.0 0.07106314154930185 0.0 0.0 0.06645480449892524 0.016117657545814148 7.58780109272235e-11 10.119884062267472 0.003514357357673803 LSSERPSS(ph)DGEGVVENGITTCNGK ddPTM_PC-9_Lapatinib_30min_R1 3 LSSERPSSDGEGVVENGITTCNGK 24 1 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 LS(0.046)S(0.192)ERPS(0.138)S(0.625)DGEGVVENGITTCNGK;LS(0.003)S(0.01)ERPS(0.157)S(0.83)DGEGVVENGITTCNGK;LS(0.099)S(0.082)ERPS(0.17)S(0.649)DGEGVVENGITTCNGK 136.67 8.96e-07 91632000.0 127147.0 125823.0 158497.0 149091.0 172897.0 147513.0 124207.0 130019.0 163871.0 114967.0 True False 125333.86046409616 125531.66457404212 145465.9884761133 160055.6494929959 162727.53838858072 141204.2128595981 130637.83071048134 136060.15739769576 145414.12234186896 134838.89276610204 0.9295082293615851 0.930975195649191 1.078813282221514 1.1870139705955316 1.2068293876519414 1.0472068552545715 0.9688438404570107 1.009057213438501 1.0784286295951067 1.0 17.040877160183555 -5.260704647386617 22.949428067632567 1.0766975344285223 0.9302416761467914 0.38054241326640237 0.0721612146735308 22.628926706909745 706686.9518773303 0.021346638899140766 0.050053745562259104 5.48649960935373e-06 5.260704647386617 -0.1464558582817309 LSSFS(ph)CGQASATPFTDIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSSFSCGQASATPFTDIK 18 0 Q14680-3;Q14680-4;Q14680-5;Q14680-2;Q14680-8;Q14680-6;Q14680;Q14680-7 Q14680-3 MELK Maternal embryonic leucine zipper kinase 1 LS(0.012)S(0.355)FS(0.63)CGQAS(0.003)ATPFTDIK 108.77 0.00026451 2644100.0 9017.2 9836.0 9116.6 10056.0 14171.0 13774.0 15495.0 21702.0 20947.0 16153.0 True False 10543.633862181861 10812.453076140593 9333.97431889803 9492.594921991878 11394.29427737467 13051.667192258812 14027.201425914745 21132.345495169702 21253.310247169342 19081.411032922362 0.5525604916738215 0.566648507151027 0.4891658327989233 0.4974786668351573 0.5971410739863722 0.6839990590706289 0.7351239068071397 1.107483375244563 1.1138227781215795 1.0 14.219880239306402 -7.504753487447541 1.5286628243472318 1.1004017759580167 0.5419219521757914 0.9293336950793962 0.06248759516426489 0.0950858651848345 0.4283369795935662 0.04252599887786961 0.020608605617595453 3.127854283879827e-08 7.504753487447541 -0.5584798237822253 LSSGLVS(ph)PAPSFYSK ddPTM_PC-9_AZD4547_30min_R2 1 LSSGLVSPAPSFYSK 15 0 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 LS(0.001)S(0.016)GLVS(0.846)PAPS(0.134)FYS(0.003)K 88.507 0.0048266 10137000.0 28750.0 23720.0 34782.0 48057.0 43271.0 39322.0 26260.0 41324.0 32614.0 33701.0 True False 37891.90196285081 31387.026130118596 34320.76795384493 36978.20112324863 37263.56856182871 36863.18912386116 28597.08912763927 34938.32533105134 34337.90945719936 32521.138247786075 1.165146855381987 0.9651269242476566 1.0553372299686148 1.1370512569856308 1.1458260863414116 1.133514726421689 0.8793385062279011 1.07432664456109 1.0558643180189724 1.0 14.989090132525066 LSSGLVS(ph)PAPSFYSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSSGLVSPAPSFYSK 15 0 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 LSSGLVS(0.995)PAPS(0.005)FYSK 150.12 0.00013753 7679100.0 22613.0 21187.0 27962.0 29049.0 26296.0 21839.0 27167.0 23403.0 25495.0 16777.0 True False 26440.934272891645 23290.305339995 28628.720126475542 27421.47870812869 21143.487567415465 20693.724394637724 24593.545087952636 22788.696047528174 25867.81614319869 19818.53729334106 1.3341516521391152 1.175177814349621 1.444542536249366 1.3836277774819528 1.0668540899090257 1.044160024947488 1.2409364386450434 1.149867707703387 1.3052333661319273 1.0 14.274562867930848 -6.257128003420655 24.976123900185073 1.1428059518229217 1.3308728388454774 0.4602032240849492 0.10578797609945727 372.3632338850978 2157126.6709355838 0.032403361246621624 0.040395285043596865 5.531870395187958e-07 6.257128003420655 0.1880668870225557 LSSGLVS(ph)PAPSFYSK ddPTM_PC-9_Lapatinib_30min_R1 2 LSSGLVSPAPSFYSK 15 0 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 LSSGLVS(0.968)PAPS(0.032)FYSK;LS(0.278)S(0.278)GLVS(0.44)PAPS(0.004)FYSK 162.79 2.2381999999999997e-05 13008800.0 62589.0 57571.0 70871.0 56195.0 65529.0 56871.0 58843.0 60311.0 67527.0 52458.0 True False 61696.46938258309 57437.697886651666 65044.259949971245 60327.76776102463 61674.71305497085 54438.75990277609 61889.60261898979 63113.269236130174 59921.39816916587 61525.295404108714 1.0027821723951114 0.9335623260220206 1.0571954108102914 0.9805360114857066 1.0024285564153856 0.8848191551980849 1.0059212590933249 1.0258100968323902 0.9739310924976764 1.0 15.90889205912471 LSSGPEQITLEASSTEGHPGAPS(ph)PQHTDQTEAFQK ddPTM_PC-9_Lapatinib_30min_R1 1 LSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQK 35 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 LSSGPEQITLEAS(0.06)S(0.175)T(0.175)EGHPGAPS(0.588)PQHT(0.002)DQT(0.001)EAFQK 96.686 5.809300000000001e-16 13495000.0 27413.0 18791.0 43670.0 22944.0 35120.0 33964.0 26648.0 18996.0 35405.0 21524.0 True False 27022.0855930715 18747.49059401561 40079.62117107486 24631.378298940264 33054.310648576604 32511.438893951014 28027.703050334592 19878.62350830742 31417.316068821674 25244.394721072782 1.0704192313438512 0.7426397345295083 1.5876641770942663 0.975716731222682 1.3093722790265392 1.2878676337132402 1.110254508377594 0.7874470244958467 1.2445264153073965 1.0 14.623675466192767 -7.535510333835209 24.939631180831014 0.999362172095859 1.1639397897559598 0.07747772894431526 0.2329662571641411 578.1422875570396 1141460.8722936607 0.10730791882869987 0.06200161339349706 2.914000796652205e-08 7.535510333835209 0.16457761766010082 LSSLPFQK ddPTM_PC-9_Lapatinib_30min_R1 1 LSSLPFQK 8 0 H3BRV9;P61970 H3BRV9 NUTF2 Nuclear transport factor 2 0 109.86 0.017376 3206500.0 19378.0 18405.0 24581.0 19896.0 23411.0 19539.0 16110.0 15937.0 20618.0 17831.0 False True 19101.66616651001 18362.384353299825 22560.04506540398 21359.218211110343 22034.01100779689 18703.362517633628 16944.096973164596 16677.491200878903 18295.78372283476 20913.064591685976 0.9133843623331949 0.8780341242096016 1.0787536645572626 1.021333727415624 1.05360029426565 0.8943386769373429 0.8102158772034181 0.79746758911217 0.8748494818931645 1.0 14.352116868892832 -6.939158514391389 6.290753151081662 0.8534473667558402 0.9891169351682124 0.35089980771404805 0.07634785117654068 0.2100664812137803 16.237402663797585 0.02816882653901736 0.02472570657799397 1.150380431647714e-07 6.939158514391389 0.1356695684123722 LSSPAAFLPACNS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 2 LSSPAAFLPACNSPSK 16 0 Q86YS7-3;Q86YS7;Q86YS7-2;Q86YS7-4;Q86YS7-5;H0YFE9 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 LSSPAAFLPACNS(0.884)PS(0.115)K;LSSPAAFLPACNS(0.999)PS(0.001)K 164.97 4.6396e-05 91407000.0 198152.0 216149.0 229960.0 166198.0 206535.0 260544.0 228824.0 263552.0 230825.0 247732.0 True False 261160.2141823589 286014.9372259275 226910.58014680518 127883.61883350335 177861.180303605 244252.14249242877 249188.89270917483 222826.09422246716 243025.93826142277 239058.97808375236 1.0924509770591573 1.196419977691549 0.9491824233738209 0.5349458943503906 0.7440054405373255 1.0217233606966103 1.0423741233507389 0.9320967403466515 1.0165940648180996 1.0 17.86700706290292 -5.364018374719075 5.390513127841383 0.8901066101239046 1.1422176541102338 0.2910925663127687 0.14980453573824132 0.2809191100435458 11.86559583228571 0.04404584716777595 0.09440386771957972 4.3249553204123405e-06 5.364018374719075 0.2521110439863292 LSSPAAFLPACNS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSSPAAFLPACNSPSK 16 0 Q86YS7-3;Q86YS7;Q86YS7-2;Q86YS7-4;Q86YS7-5;H0YFE9 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 LSSPAAFLPACNS(0.961)PS(0.039)K;LSSPAAFLPACNS(0.974)PS(0.026)K 123.42 4.1589e-05 67811000.0 60516.0 72989.0 59172.0 66845.0 77100.0 58052.0 75116.0 59723.0 54186.0 56456.0 True False 70760.16355451786 80234.86555250362 60582.88489105965 63099.89136441394 61992.80846698103 55007.65092529463 68000.46868725464 58155.33453174915 54978.36774015935 66691.02589455001 1.061014770808922 1.2030833905504579 0.9084113503794591 0.9461526572433557 0.9295524792946255 0.8248133866207306 1.0196344676834794 0.8720113951118812 0.8243742992811299 1.0 16.02520502149195 -5.272308558549873 24.997873637279096 0.9131076519414618 1.1320490793210882 0.6107563572968648 0.0690889588932291 383.2735507300318 881486.5226153829 0.017381314992307308 0.036756465601723465 5.341846957603073e-06 5.272308558549873 0.2189414273796264 LSSPAAFLPACNS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 1 LSSPAAFLPACNSPSK 16 0 Q86YS7-3;Q86YS7;Q86YS7-2;Q86YS7-4;Q86YS7-5;H0YFE9 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 LSSPAAFLPACNS(0.973)PS(0.027)K 94.454 0.0025976999999999997 29851000.0 22739.0 36171.0 31098.0 33858.0 34491.0 40328.0 40393.0 35299.0 38379.0 34067.0 True False 22414.737690178114 36087.24827183961 28541.24248175145 36348.03026697699 32462.30719191505 38603.26544915958 42484.35189553307 36939.12040533502 34056.3528712133 39955.43555857586 0.560993451249391 0.9031874579100666 0.7143269015278069 0.9097142793923418 0.8124628536291224 0.9661580435674652 1.0632934243264536 0.9245080147150735 0.8523584437287804 1.0 15.286104161049954 -3.8066154054885963 0.4503915520818823 0.9611431373386028 7.370444012144065e-13 0.5630877023328482 0.09170779904174944 9.218525469940197 0.7399938542725286 0.06080063563266502 5.682246867652758 0.00015609341943153415 3.8066154054885963 -0.9611431373378657 LSSPAAFLPACNSPS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 LSSPAAFLPACNSPSK 16 0 Q86YS7-3;Q86YS7;Q86YS7-2;Q86YS7-4;Q86YS7-5;H0YFE9 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 LSSPAAFLPACNS(0.319)PS(0.681)K 161.75 6.0088000000000005e-05 31643000.0 15314.0 24147.0 22039.0 22039.0 28635.0 24553.0 26229.0 30189.0 25311.0 19087.0 True False 15095.619551756345 24091.08910508726 20227.03849300021 23659.821579948784 26950.745598576053 23502.925425838515 27587.009280517337 31591.691150362873 22460.208643353915 22386.16251817118 0.6743281497890944 1.0761598413989966 0.9035509537010474 1.0568949260840823 1.203901989753703 1.0498863039505248 1.2323241760674504 1.4112151256259053 1.003307673886609 1.0 14.45031961919596 -4.0756608571931725 0.5766540427296796 1.1761770826183608 1.1442769295917354e-11 0.4655674402601183 0.13757483685734326 6.953556774329389 0.9620812243361903 0.06766463553195534 6.53038127518106 8.401157811874493e-05 4.0756608571931725 -1.176177082606918 LSSQIS(ph)AGEEK ddPTM_PC-9_AZD4547_30min_R2 2 LSSQISAGEEK 11 0 Q86UE4;E5RJU9;H0YB56 Q86UE4 MTDH Protein LYRIC 1 LSS(0.001)QIS(0.999)AGEEK;LS(0.001)S(0.016)QIS(0.983)AGEEK 106.55 0.00242 19173700.0 51068.0 65028.0 61460.0 45426.0 40912.0 39315.0 70450.0 91319.0 76564.0 42526.0 True False 67306.5617196126 86047.02930815161 60645.00024274942 34953.73752470383 35232.074992524686 36856.626834967756 76719.9135202662 77207.74685186034 80611.01673149616 41037.17768390701 1.6401362256938858 2.096806704665158 1.4778063128481602 0.8517578327130221 0.858540401191897 0.898127720158039 1.8695221711202719 1.881409765714416 1.9643411482244375 1.0 15.324643893110299 -11.15638683376095 5.1344830406593065 0.9936093059734067 1.4867445810384843 0.09844926711151847 0.4550253759366145 0.038224824192106 0.0027284297244401937 0.5059156755308581 0.12180672063215055 6.9761075304893224e-12 11.15638683376095 0.4931352750650776 LSSQIS(ph)AGEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSSQISAGEEK 11 0 Q86UE4;E5RJU9;H0YB56 Q86UE4 MTDH Protein LYRIC 1 LS(0.001)S(0.053)QIS(0.946)AGEEK 82.102 0.014318 3774000.0 19999.0 29109.0 13391.0 9132.4 21804.0 12059.0 20131.0 18631.0 16517.0 20016.0 True False 23384.435701745017 31998.749145320915 13710.292225650312 8620.741235640273 17531.66272132365 11426.604811343766 18224.04594418133 18141.955991176244 16758.52987790596 23644.742353431197 0.9889909288164265 1.3533135048383147 0.5798452789510201 0.36459442470470727 0.7414613557326223 0.483261971754393 0.7707441118104108 0.7672723060373539 0.7087634801600641 1.0 14.529231801004618 -5.26868310067461 24.982332616664998 0.6562558084026737 1.1711522246448938 0.5319077845000881 0.184609502728559 348.4799244392997 1201849.4737720613 0.047118758209413025 0.1013708650604943 5.386626946698947e-06 5.26868310067461 0.51489641624222 LSSQIS(ph)AGEEK ddPTM_PC-9_Lapatinib_30min_R1 2 LSSQISAGEEK 11 0 Q86UE4;E5RJU9;H0YB56 Q86UE4 MTDH Protein LYRIC 1 LSSQIS(1)AGEEK;LSS(0.002)QIS(0.998)AGEEK 130.47 0.00020762 19664400.0 42930.0 90614.0 33437.0 19844.7 51741.0 49040.0 86342.0 56334.0 71081.0 40996.0 True False 42317.8103276022 90404.18885030772 30687.938930552562 21304.145437978565 48697.6961067199 46942.67351782347 90812.36628534943 58951.4832973779 63075.10926388684 48082.10397626371 0.8801156111740219 1.8802045121598008 0.6382403512479824 0.4430784777740925 1.0128029366343887 0.9763024001819318 1.8886936879921066 1.2260587291787395 1.3118209073177123 1.0 15.553212406416131 -7.096241641784842 24.992563377459366 1.3836300786981446 0.9756080878548765 0.17527673755611572 0.4072406079003492 90.32925395818704 23448.655685322632 0.1618038019895298 0.12533271052031317 8.012321331640823e-08 7.096241641784842 -0.40802199084326807 LSSS(ph)LGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSSSLGR 7 0 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 LSS(0.001)S(0.998)LGR;LS(0.003)S(0.02)S(0.977)LGR 110.12 0.0095119 44960000.0 169260.0 192670.0 210292.0 216070.0 233950.0 218090.0 199547.0 220160.0 199907.0 170362.0 True False 197912.37496261625 211797.0042883293 215306.15881685115 203964.2984083911 188109.17692412666 206652.97647449697 180644.46356482836 214381.03327880247 202830.26168811176 201247.28201515015 0.983428809476876 1.0524216882212847 1.069858716405634 1.013500884911511 0.9347166085451308 1.0268609563578597 0.8976243641950366 1.0652617572378622 1.0078658437376682 1.0 17.618609773193292 -6.000914048686573 24.945979462279215 0.98795241602586 1.0377424180334205 0.15875123179683526 0.048189637316285686 57.682710579701045 1574372.966587307 0.013430353186857001 0.019641022807418973 9.978975383951879e-07 6.000914048686573 0.04979000200756045 LSSS(ph)LGR ddPTM_PC-9_Lapatinib_30min_R1 1 LSSSLGR 7 0 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 LS(0.062)S(0.35)S(0.588)LGR 71.877 0.040286 15631000.0 108100.0 96929.0 98885.0 91282.0 111170.0 115150.0 92341.0 76330.0 105740.0 72722.0 True False 106558.47417688776 96704.56685580008 90755.05700713852 97995.18278782524 104631.19916862936 110225.3029277605 97121.96515201706 79876.57045636493 93830.44770843683 85291.90080402582 1.2493387200002248 1.1338071486763672 1.064052461624291 1.1489389011623459 1.226742494683513 1.2923302434192885 1.138700911065085 0.936508269875429 1.1001097035465293 1.0 16.380121131355274 -7.601645797382473 6.5517073641438355 1.0154631830844036 1.181126472186644 0.5471463246275647 0.07057043733762246 0.179690640348712 12.017464681343382 0.03582042020054434 0.020476373369928007 2.5023854293424428e-08 7.601645797382473 0.16566328910224026 LSSS(ph)PGLFGAFSVR ddPTM_PC-9_AZD4547_30min_R2 1 LSSSPGLFGAFSVR 14 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 LSS(0.034)S(0.966)PGLFGAFSVR 115.24 0.00016189 27339000.0 109800.0 123380.0 127780.0 197980.0 140340.0 128000.0 117340.0 141830.0 117640.0 118900.0 True False 144714.11601812262 163260.1721725986 126085.55371003132 152338.7697605085 120856.2134447329 119996.13976537887 127783.03268229947 119913.43242917003 123858.21023318006 114737.34719034361 1.2612642662728555 1.422903493678985 1.0989059517025577 1.3277173779151958 1.0533293335101985 1.0458333115050253 1.1137004280769514 1.0451124709223019 1.0794934105257408 1.0 16.80797554178215 -5.986450918821778 0.9239831014246142 1.0505834651925505 1.3319020618836281 0.5929636959433617 0.08577841795197448 0.4335049330202883 0.7456007738746536 0.03632651457325521 0.082973924680965 1.031689667803775e-06 5.986450918821778 0.2813185966910776 LSSS(ph)PGLFGAFSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSSSPGLFGAFSVR 14 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 LS(0.003)S(0.019)S(0.976)PGLFGAFS(0.002)VR 85.271 0.006959600000000001 23092000.0 58394.0 48757.0 56029.0 58197.0 65557.0 48465.0 48905.0 67311.0 38190.0 29335.0 True False 68278.95086592823 53597.27273621262 57364.943851165764 54936.41076721969 52711.57645486219 45923.410082243616 44272.36435846151 65544.15757189972 38748.45650161826 34653.20328426775 1.9703503397888262 1.5466758526345328 1.6554008984563036 1.5853198423408188 1.521116995230071 1.3252284270958707 1.2775836044733209 1.8914314222043707 1.1181782008363341 1.0 15.080701098397524 -1.522881494854768 0.04724612757541467 1.1877502205140066e-08 4.184480111831819 0.5161211854344483 0.20671812958462332 491.30979380729633 1.7633722849032514 38.399458825804125 153.36321499007144 0.02999981006672838 1.522881494854768 4.184480099954317 LSSS(ph)PGLFGAFSVR ddPTM_PC-9_Lapatinib_30min_R1 1 LSSSPGLFGAFSVR 14 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 LS(0.009)S(0.026)S(0.965)PGLFGAFSVR 143.05 0.00015969 15398000.0 34956.0 38074.0 38764.0 32329.0 34889.0 35154.0 31831.0 34780.0 34803.0 22267.0 True False 34457.52102985472 37985.84199225957 35576.973553367214 34706.582506382525 32836.89761441313 33650.545367976505 33479.05342972085 36396.005770632386 30883.1196481627 26115.82128108752 1.3194117335612212 1.4545145482278228 1.3622766510173374 1.328948537854953 1.257356498996754 1.2885118566937606 1.2819452648791718 1.3936381850257775 1.1825444551700754 1.0 14.67263645333511 -13.94795799465492 0.1605079867021588 3.295484063626322e-10 1.41495586375908 0.7483772219687621 0.05979515520823423 54.813849461633545 0.5953737462703714 17.67727037858598 0.2634057120669032 1.1273064849795856e-14 13.94795799465492 1.4149558634295316 LSSS(ph)PPSGSGGGGGASSSSHCSGESQCR ddPTM_PC-9_AZD4547_30min_R2 2 LSSSPPSGSGGGGGASSSSHCSGESQCR 28 0 Q9Y4X0-2;Q9Y4X0-3;Q9Y4X0 Q9Y4X0-2 AMMECR1 AMME syndrome candidate gene 1 protein 1 LS(0.032)S(0.127)S(0.469)PPS(0.111)GS(0.261)GGGGGASSSSHCSGESQCR;LS(0.02)S(0.055)S(0.535)PPS(0.286)GS(0.096)GGGGGAS(0.005)S(0.002)S(0.001)SHCSGESQCR 112.05 3.8532e-11 8520600.0 1349.4699999999998 2658.6 16247.9 49674.0 22857.0 14569.900000000001 8467.7 24296.0 8126.799999999999 14745.400000000001 True False 1778.5733892802884 3517.9404582433967 16032.442229810733 38222.42675564962 19683.700090539132 13658.841849746832 9221.308895891509 20541.61146653817 8556.366056808976 14229.168034150462 0.12499489675093126 0.24723444475462136 1.1267308244116843 2.686202500660233 1.383334573272142 0.9599185150505758 0.648056785453659 1.4436270214279316 0.6013258144308523 1.0 13.79656369088018 -5.273712843553297 4.885786238136393 1.2790790424910756 0.16777075665281715 0.3630609695974474 0.5537861001589219 0.19141664452810156 13.69311693435328 0.1557466714580939 0.37450317123355126 5.32460206735125e-06 5.273712843553297 -1.1113082858382586 LSSS(ph)SATLLNSPDR ddPTM_PC-9_AZD4547_30min_R2 3 LSSSSATLLNSPDR 14 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40 Q14244-5 MAP7 Ensconsin 1 LSS(0.04)S(0.944)S(0.016)ATLLNSPDR;LSS(0.039)S(0.941)S(0.019)ATLLNSPDR;LS(0.012)S(0.174)S(0.806)S(0.007)ATLLNSPDR 184.51 6.5202e-06 88075600.0 87108.0 98892.5 195635.0 249042.0 178773.0 213236.0 209060.0 194552.0 186697.0 185958.0 True False 114806.53204104399 130857.56667676044 193040.75207436175 191629.21456054432 153953.45479660286 199902.31921101807 227665.93499711613 164488.4587602049 196565.4222705204 179447.66702120972 0.6397772339245541 0.7292241178108702 1.0757495780178932 1.0678835659529349 0.8579295420898753 1.11398672676748 1.268703788554728 0.9166374881918262 1.0953913502106853 1.0 17.453203641397934 -5.1917015384864325 4.082101355209336 1.051104041279445 0.6618389654543432 0.6540686857576006 0.10673827328376712 0.13584031050701034 4.395761002244058 0.028434864660056014 0.08322558091177021 6.431295453476226e-06 5.1917015384864325 -0.38926507582510184 LSSS(ph)SATLLNSPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSSSSATLLNSPDR 14 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40 Q14244-5 MAP7 Ensconsin 1 LSS(0.037)S(0.962)S(0.001)ATLLNSPDR;LS(0.006)S(0.138)S(0.816)S(0.04)ATLLNSPDR 225.29 2.0755e-20 38093100.0 44394.6 54725.0 64693.0 82766.0 74667.0 83756.0 87846.0 67919.0 74335.0 50293.0 True False 51909.7289466818 60157.73633507466 66235.52646956878 78128.88935099253 60036.537351544284 79363.68791598878 79524.59093003576 66136.19821612896 75422.0087469964 59410.72278083108 0.8737434341302193 1.0125737159771537 1.1148749479772317 1.3150637745851643 1.0105336973095222 1.335847877306006 1.338556193355965 1.1132030569651286 1.2695016188446606 1.0 15.858435719777782 -5.085473470777017 1.6306079566090408 1.207174930926366 0.8472366279751509 0.42699403540644043 0.11969104357855541 0.5234255505038548 2.029076088255998 0.03328398002909943 0.2485418174364963 8.213467239184308e-06 5.085473470777017 -0.3599383029512151 LSSS(ph)SATLLNSPDR ddPTM_PC-9_Lapatinib_30min_R1 4 LSSSSATLLNSPDR 14 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40 Q14244-5 MAP7 Ensconsin 1 LS(0.182)S(0.125)S(0.658)S(0.035)ATLLNSPDR;LSS(0.026)S(0.949)S(0.026)ATLLNSPDR;LS(0.022)S(0.134)S(0.842)S(0.002)ATLLNSPDR;LSS(0.002)S(0.997)S(0.002)ATLLNSPDR 261.17 1.9015e-45 108115700.0 239018.0 233615.0 238822.0 173987.0 226569.0 188746.0 182222.0 218408.0 186159.0 120531.0 True False 235609.55948946727 233074.078820763 219186.97703957968 186782.58438361762 213242.6568717928 180673.7735684157 191656.5635409061 228556.03301760368 165191.81307882414 141364.62275253804 1.6666797880676774 1.6487440371044206 1.5505079897059637 1.3212823742371862 1.5084584298369959 1.2780692230522852 1.3557604428118146 1.6167838074855274 1.1685512956660744 1.0 17.10906159765853 -1.5228787453545534 0.041817327215605556 5.015570614039747e-11 3.8074502980401634 0.6494818502466484 0.12554626312851308 477.26765885850887 1.523260117975462 37.01609153085669 126.38502054215083 0.029999999994873353 1.5228787453545534 3.8074502979900076 LSSS(ph)SSNDSGNK ddPTM_PC-9_AZD4547_30min_R2 2 LSSSSSNDSGNK 12 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 LS(0.007)S(0.054)S(0.435)S(0.196)S(0.09)NDS(0.216)GNK;LS(0.103)S(0.103)S(0.627)S(0.129)S(0.037)NDS(0.001)GNK 116.98 0.00065179 4358100.0 30985.0 33121.0 30657.0 31488.0 30294.0 31857.0 29957.0 34481.0 44765.0 46610.0 True False 40837.58547196286 43826.71553354379 30250.468149072032 24228.928084750463 26088.201012503487 29864.976753950603 32623.114965601246 29152.753744554768 47131.1865104412 44978.19808697985 0.9079417853287547 0.9743990955082439 0.6725584713414485 0.538681608318235 0.5800188118264217 0.6639878435369296 0.7253095133449751 0.6481529937721942 1.0478673783084385 1.0 15.456938244688072 -8.26561810069647 24.926909805606282 1.023933741928847 0.7096035214714147 0.48360765024643604 0.1280948436402247 344.1946799868497 2053146.4960210144 0.12419777502892564 0.03655126179547641 5.424777115602529e-09 8.26561810069647 -0.3143302204574323 LSSS(ph)SSNDSGNK ddPTM_PC-9_Lapatinib_30min_R1 1 LSSSSSNDSGNK 12 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 LS(0.001)S(0.08)S(0.915)S(0.005)SNDSGNK 174.72 0.0010935 4116500.0 13830.0 32936.0 17089.0 25849.0 30457.0 12237.0 35210.0 33403.0 20436.0 20381.0 True False 13632.781663888616 32859.73871558179 15684.008385447642 27750.021689736204 28665.579140765905 11713.652035840256 37033.00151614686 34955.02532364672 18134.282479379734 23903.828694024563 0.5703179117618307 1.374664248819521 0.656129550885223 1.1609028011764955 1.1992045085200798 0.49003246240500437 1.5492497871441115 1.4623191025622064 0.7586350584880533 1.0 14.544954093801335 -7.2790673901205585 24.980853968469876 1.2310775178354876 0.9429388418582371 0.13497560864987546 0.3401620876559006 1664.43096737989 2358674.1482120776 0.13712866717166916 0.09267721230897738 5.259356498417302e-08 7.2790673901205585 -0.2881386759772505 LSSS(ph)VSAMR ddPTM_PC-9_Lapatinib_30min_R1 1 LSSSVSAMR 9 0 E3W994;J3KR49;O75122;A0A0U1RQI6;H7C4M5;E7ERI8;E7EW49;O75122-3 E3W994;E7ERI8 CLASP2 CLIP-associating protein 2 1 LS(0.009)S(0.158)S(0.823)VS(0.009)AMR 82.831 0.015203 3669900.0 27871.0 28222.0 31859.0 28089.0 29133.0 32793.0 29974.0 27777.0 35403.0 19170.0 True False 27473.554429084576 28156.653692954525 29239.675999296407 30154.758762157155 27419.454217681752 31390.519834216662 31525.90705609161 29067.620824923946 31415.54132988259 22483.508957580627 1.2219424681849531 1.2523247036784764 1.3004943336230372 1.3411945092311786 1.219536250743321 1.3961575078623532 1.4021791311832674 1.2928418281935212 1.3972703900069123 1.0 14.456579591293506 -10.488125240270367 4.303023156896498 0.9999892967647759 1.3140162243916087 0.6680359033326358 0.06635577317818424 48339962.941345446 158661702.13610828 9473.505235555138 0.017169932478373652 3.249935634035463e-11 10.488125240270367 0.3140269276268328 LSSSDRYS(ph)DASDDSFSEPR ddPTM_PC-9_AZD4547_30min_R2 2 LSSSDRYSDASDDSFSEPR 19 1 Q9NRF8 Q9NRF8 CTPS2 CTP synthase 2 1 LS(0.004)S(0.011)S(0.134)DRY(0.134)S(0.716)DAS(0.001)DDSFSEPR;LS(0.001)S(0.004)S(0.055)DRY(0.15)S(0.762)DAS(0.021)DDS(0.003)FS(0.003)EPR 74.308 0.0020716 4096900.0 13686.0 14315.8 18559.9 23931.0 21438.0 21996.8 17173.3 21311.0 19248.4 17357.0 True False 18037.863313515696 18943.102389272837 18313.783599176764 18414.077680264334 18461.7037468162 20621.336618680354 18701.69043090965 18017.87462806202 20265.831127612568 16749.336713059627 1.0769300075895776 1.1309762717052974 1.0934035128028277 1.099391456254306 1.1022349161099272 1.2311733277534322 1.1165630467221876 1.0757366059763611 1.2099482788360865 1.0 14.031816344389906 -6.592207244358647 24.999996146571295 1.13477599274929 1.1017438118417304 0.03435783002095727 0.06202468468850258 152.38498051442437 54947.55545617657 0.019529931748159486 0.019529937376387196 2.557365226695271e-07 6.592207244358647 -0.03303218090755955 LSSSDRYSDAS(ph)DDSFSEPR ddPTM_PC-9_Lapatinib_30min_R1 1 LSSSDRYSDASDDSFSEPR 19 1 Q9NRF8 Q9NRF8 CTPS2 CTP synthase 2 1 LSSSDRY(0.009)S(0.169)DAS(0.794)DDS(0.021)FS(0.007)EPR 72.167 0.0027340999999999997 3759200.0 9709.2 10645.0 10189.0 8076.4 6492.4 10437.0 9236.2 9366.1 13475.0 9930.1 True False 9570.745027550789 10620.352156526851 9351.299750677399 8670.365398080603 6110.529796549507 9990.633839835315 9714.405242926312 9801.283198629097 11957.303601959386 11646.504553973462 0.8217697407146523 0.9118918133169392 0.8029275828932722 0.744460739949869 0.5246664154237389 0.8578225160635677 0.8341047906611626 0.8415643640722377 1.0266860367027364 1.0 13.50760940573154 -8.072517210931332 1.6389939092264478 1.0210663650189704 0.7769374302505982 0.45085322901719904 0.09834648853044232 0.38729323002658017 1.857907342820932 0.09634185298502765 0.03089370714335946 8.46219032792276e-09 8.072517210931332 -0.24412893476837216 LSSSPPRAS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 2 LSSSPPRASPVR 12 1 Q9Y2K6 Q9Y2K6 USP20 Ubiquitin carboxyl-terminal hydrolase 20 1 LSSSPPRAS(1)PVR;LSSSPPRAS(1)PVR 77.387 0.0083137 17438800.0 45455.0 47762.0 59821.0 81477.0 85000.0 61433.0 48121.0 62855.0 44212.0 63299.0 True False 59908.74447726548 63200.132463183996 59027.73445365296 62693.73645710151 73199.21720680004 57591.584798488446 52403.675777270735 53142.20401421045 46548.956059413096 61082.92127671609 0.9807773306366375 1.0346612627918788 0.9663541497343786 1.0263709584727971 1.1983581609529617 0.9428426734469477 0.8579104384983998 0.8700010232560288 0.76206172014168 1.0 15.898481439893951 -6.9957598669665195 24.9988932432227 0.8671909600387311 1.0394076507357815 0.502661171922663 0.07938293229511482 99.43233561453829 586226.0419106381 0.028175734179907864 0.024749338115730685 1.0098110832949394e-07 6.9957598669665195 0.17221669069705037 LSSSPPRAS(ph)PVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSSSPPRASPVR 12 1 Q9Y2K6 Q9Y2K6 USP20 Ubiquitin carboxyl-terminal hydrolase 20 1 LSSS(0.001)PPRAS(0.998)PVR 56.551 0.035903 1638000.0 14186.0 14875.0 17484.0 15416.0 17931.0 13091.0 16198.0 12926.0 12235.0 13344.0 True False 16587.40961372841 16351.691694549745 17900.88486843924 14552.291499346344 14417.54926876051 12404.48491461159 14663.608176635511 12586.70619622908 12413.913728654083 15763.161568954112 1.0522895131898966 1.0373357922534243 1.1356151359696407 0.9231835527212635 0.9146356335746875 0.786928742711265 0.9302453770134416 0.7984886877654589 0.7875268977197795 1.0 13.94426930028346 -5.956818810412309 3.2717201353761354 0.8603587934590788 1.0709192237190335 0.628195627539027 0.06993900569897976 0.14829552030653975 3.276689676101213 0.020232789727899634 0.03063527549076192 1.1045393425094822e-06 5.956818810412309 0.21056043025995463 LSSSPPRAS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 2 LSSSPPRASPVR 12 1 Q9Y2K6 Q9Y2K6 USP20 Ubiquitin carboxyl-terminal hydrolase 20 1 LSSSPPRAS(1)PVR;LSSSPPRAS(1)PVR 103.11 0.0010372 9588700.0 75022.0 58163.0 69695.0 55060.0 53798.0 58943.0 47697.0 50005.0 54017.0 41581.0 True False 73952.17252265017 58028.32714702408 63964.94613048005 59109.29607477564 50633.70741093747 56422.14529284399 50166.51727678664 52328.414852227485 47933.03663577288 48768.22044680021 1.5164008824829354 1.189879938521141 1.3116112407722051 1.2120453757228276 1.038252102435689 1.1569449279863147 1.028672295547708 1.0730023440020942 0.9828744251199732 1.0 15.573653708916932 -1.5228787504696686 0.28936808679395115 0.9918667457383463 4.738114226893853 0.8069928082533019 0.06938209597943934 21.996319118688163 0.31202269297289065 0.071157031579482 42.13197211221023 0.029999999641533714 1.5228787504696686 3.746247481155507 LSSSS(ph)SNDSGNK ddPTM_PC-9_Lapatinib_30min_R1 1 LSSSSSNDSGNK 12 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 LS(0.001)S(0.043)S(0.332)S(0.605)S(0.017)NDS(0.001)GNK 84.169 0.010355 8377000.0 9955.2 33665.0 22287.0 22575.0 31618.0 14139.0 34182.0 31536.0 20287.0 19441.0 True False 9813.237022439915 33587.05076087143 20454.648890307897 24235.240807992363 29758.291403379717 13534.307929618815 35951.776706189485 33001.27768782813 18002.064428419297 22801.35094649582 0.43037963169230736 1.4730289814706437 0.8970805694059732 1.0628861800715763 1.3051108889648078 0.5935748263941707 1.5767388866805132 1.4473387022228112 0.7895174487977393 1.0 14.476831684030303 -4.743149812603462 24.826355298371727 1.134954958219839 0.43037718907263967 0.3198177510902015 0.30469893723100155 1336.761529481013 1814423.3124585287 0.07357351167701522 2.4045053041854123 1.806550837479567e-05 4.743149812603462 -0.7045777691471994 LSSSSATLLNS(ph)PDR ddPTM_PC-9_AZD4547_30min_R2 4 LSSSSATLLNSPDR 14 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40 Q14244-5 MAP7 Ensconsin 1 LSSSSATLLNS(1)PDR;LSSSSAT(0.008)LLNS(0.992)PDR;LSSSSATLLNS(1)PDR;LSSSSATLLNS(1)PDR 233.28 9.811399999999999e-27 70513600.0 91490.1 75359.5 107476.0 127313.0 135741.0 129939.0 100815.8 136755.6 100995.0 117002.0 True False 120582.0486877013 99717.98463965752 106050.7980164291 97962.95481624235 116895.70521021429 121813.89378885612 109788.21089391688 115623.16435105834 106333.38951462116 112905.79559263699 1.067988122795398 0.8831963329804524 0.9392856890983643 0.8676521369167951 1.0353383951340536 1.078898502503445 0.9723877354359353 1.0240675754876711 0.9417885853997344 1.0 16.784760017750166 -6.28455832754094 24.867177435445544 1.011639812338458 0.9354891931597493 0.236719853103741 0.06058217766649298 995.7183372392325 1071010.1525735254 0.018510342798043967 0.021002007383975767 5.193279209404094e-07 6.28455832754094 -0.07615061917870869 LSSSSATLLNS(ph)PDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LSSSSATLLNSPDR 14 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40 Q14244-5 MAP7 Ensconsin 1 LSSSSATLLNS(0.999)PDR;LSSSSATLLNS(1)PDR;LSSSSATLLNS(1)PDR;LSSSSATLLNS(1)PDR 206.49 8.2743e-11 61728600.0 80847.0 83224.1 90439.0 88768.0 116996.0 92759.0 89484.0 86075.0 81333.0 72747.1 True False 94532.80029896367 91486.03863908413 92595.40875181755 83794.61674973897 94071.47366281338 87894.5547471131 81007.42771194306 83815.62245400129 82522.34125808107 85935.5733642734 1.1000427017371186 1.0645886803045206 1.0774980037581607 0.9750864917668135 1.0946744168919733 1.0227959307903347 0.9426530194726187 0.9753309272600554 0.9602814995866271 1.0 16.390967843769864 -7.04754925297782 4.914641219020279 0.9683959528369549 1.058737881712082 0.6092757493721443 0.03493166031665373 0.1453967524669122 7.923966775495414 0.013367140324704166 0.010558661296979622 8.962945321646013e-08 7.04754925297782 0.09034192887512715 LSSSSATLLNS(ph)PDR ddPTM_PC-9_Lapatinib_30min_R1 4 LSSSSATLLNSPDR 14 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40 Q14244-5 MAP7 Ensconsin 1 LSSSSATLLNS(1)PDR;LSSS(0.005)S(0.005)AT(0.001)LLNS(0.99)PDR;LSSSSATLLNS(1)PDR;LSSSSATLLNS(1)PDR 180.56 4.3923999999999995e-05 74267700.0 73209.7 88769.0 86504.0 73802.0 78362.0 77369.0 75298.9 74993.0 82042.0 56244.5 True False 72165.71625298525 88563.46083445095 79391.97503509656 79229.64527625496 73752.90122561963 74060.10822594792 79197.50860165272 78477.44855540627 72801.56601943985 65966.28688391464 1.0939787528132388 1.34255640294416 1.2035234782095288 1.2010626794210921 1.1180393002172098 1.1226963305707434 1.2005755112611076 1.1896599348316872 1.1036177638367568 1.0 16.00944128020512 -14.522878745187828 0.12847757781810018 0.38019707818836274 1.2582538477914236 0.4243905502758525 0.06599479986758489 139.1281077123209 1.1283251722576406 22.034238611887424 0.5202880367705731 3.0000000006390316e-15 14.522878745187828 0.8780567696030608 LSSSSATLLNS(ph)PDRAR ddPTM_PC-9_AZD4547_30min_R2 1 LSSSSATLLNSPDRAR 16 1 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40 Q14244-5 MAP7 Ensconsin 1 LSSSSAT(0.004)LLNS(0.996)PDRAR 119.04 0.0020998 0.0 6746.4 7218.8 13879.0 26973.0 21589.0 14875.0 11877.0 19353.0 11647.0 16784.0 True False 8891.614866162665 9552.135928672016 13694.955391622498 20754.791578695837 18591.740003265924 13944.863898515703 12934.02999120227 16362.438537698115 12262.636642178237 16196.397268652006 0.5489872049120648 0.5897691795421749 0.8455556605868745 1.2814449555930914 1.1478935527995529 0.8609855430939491 0.7985745086801481 1.0102517409453446 0.7571212559667494 1.0 13.983385314839033 -5.3483533456391505 3.7051076790374657 0.9789686516365422 0.5638363086699998 0.5394672566905285 0.14886616134603486 0.18387348345033777 4.695077043544561 0.04335987198094346 0.10221148179322195 4.483804353989705e-06 5.3483533456391505 -0.41513234296654244 LSSSSATLLNS(ph)PDRAR ddPTM_PC-9_Lapatinib_30min_R1 3 LSSSSATLLNSPDRAR 16 1 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40 Q14244-5 MAP7 Ensconsin 1 LS(0.001)S(0.001)S(0.001)S(0.001)AT(0.002)LLNS(0.994)PDRAR;LSSSSATLLNS(1)PDRAR;LSSSSAT(0.006)LLNS(0.994)PDRAR 105.17 0.0056049 13871300.0 91598.0 49120.0 60476.0 49368.0 46195.0 47936.0 38975.2 40235.3 58229.0 43411.2 True False 90291.79572298385 49006.26565792382 55503.89672411093 52998.68740682023 43477.9009228644 45885.88902427376 40993.14514888176 42104.77892418414 51670.636841446554 50914.76807821198 1.773391083394182 0.9625157396895839 1.0901335470849915 1.0409295653749628 0.8539349694390527 0.9012294616325626 0.8051327089600161 0.8269659376530105 1.0148457665970994 1.0 15.635796557323316 -2.7249940847154717 1.316921896564681 0.9172197787276835 199.999999121479 0.8628238134415183 0.09808404194105527 118.42586938854858 1.163043356987112 0.029386088982620014 70275.84692899424 0.001883674745805186 2.7249940847154717 199.0827793427513 LSSSSPGATVS(ph)PSSSDAEYDKLPDADLAR ddPTM_PC-9_Lapatinib_30min_R1 1 LSSSSPGATVSPSSSDAEYDKLPDADLAR 29 1 Q8NI08-2;Q8NI08;Q8NI08-7;Q8NI08-4;Q8NI08-3 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 1 LSSS(0.001)S(0.002)PGAT(0.06)VS(0.639)PS(0.17)S(0.054)S(0.054)DAEY(0.021)DKLPDADLAR 55.417 0.0011387 6022700.0 13580.0 12299.0 13041.0 11776.0 16424.0 9669.2 11625.0 9968.8 12430.0 12475.0 True False 13386.346709733001 12270.522421148302 11968.819319715765 12642.046323584404 15457.972610826382 9255.6708560061 12226.885618438144 10431.98684089361 11030.002506297227 14631.287128107373 0.9149124470407812 0.8386495537754888 0.8180291463710746 0.8640419816038231 1.0565012138358565 0.6325944378622392 0.8356671228842018 0.712991738153596 0.75386412758643 1.0 13.836769069849979 -6.770024329993925 24.9999213091412 0.7721257436467024 0.8887291038224523 0.20216189153222264 0.10780190984643002 291.5469608188907 848998.074178601 0.03618781713794917 0.03240931191147302 1.6981485163222643e-07 6.770024329993925 0.1166033601757499 LSST(ph)PPLSALGR ddPTM_PC-9_AZD4547_30min_R2 1 LSSTPPLSALGR 12 0 Q8N201 Q8N201 INTS1 Integrator complex subunit 1 1 LSS(0.023)T(0.763)PPLS(0.214)ALGR 132.03 0.00024253 20000000.0 148490.0 153670.0 233340.0 299330.0 195340.0 193390.0 188760.0 251440.0 151420.0 170710.0 True False 195706.73121612906 203340.8223193644 230245.7591383523 230324.09310239958 168220.41281383883 181297.29272833292 205559.2743234272 212585.72551639608 159423.75206994335 164733.4948600799 1.1880202710587606 1.2343623407739666 1.39768636204748 1.3981618813953443 1.021167024694769 1.1005490588439337 1.2478292559629334 1.2904827017538878 0.9677676795806068 1.0 17.329774398994182 -6.258930703098421 24.99769478332052 1.1261124092229238 1.3061958037605796 0.4166254524618559 0.11420630496826571 263.6395817218742 2627034.373749806 0.03610005928551991 0.044379097812896784 5.508955914021441e-07 6.258930703098421 0.18008339453765587 LSST(ph)PPLSALGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSSTPPLSALGR 12 0 Q8N201 Q8N201 INTS1 Integrator complex subunit 1 1 LS(0.003)S(0.055)T(0.939)PPLS(0.002)ALGR 112.02 0.0024526 9971300.0 96942.0 95835.0 117460.0 117200.0 122880.0 100120.0 109890.0 95210.0 90397.0 72659.0 True False 113352.3659082237 105348.86544854974 120260.6918695309 110633.66396752675 98802.54610146093 94869.5309488132 99480.4236652965 92710.83838333384 91718.88511067798 85831.50153167247 1.3206382724924812 1.2273916169307046 1.4011253412030056 1.2889633991396747 1.1511221910175025 1.1052996773428883 1.1590199622522912 1.080149324302836 1.0685923405037137 1.0 16.389219616581933 -6.354870170530293 2.56871572497849 1.093003958167288 1.3136392585840322 0.7977515702946145 0.0540469709953306 0.13260486638145574 1.7101755166296593 0.018201906424377308 0.02160978456578828 4.41702471657795e-07 6.354870170530293 0.22063530041674428 LSST(ph)PPLSALGR ddPTM_PC-9_Lapatinib_30min_R1 2 LSSTPPLSALGR 12 0 Q8N201 Q8N201 INTS1 Integrator complex subunit 1 1 LSS(0.004)T(0.691)PPLS(0.305)ALGR;LS(0.001)S(0.058)T(0.928)PPLS(0.014)ALGR 101.56 0.0065623 24603000.0 272263.0 240187.0 258035.0 193929.0 193563.0 232347.0 200029.0 213476.0 229194.0 133943.0 True False 268380.4796930813 239630.86175854524 236820.35834390434 208191.18558817913 182178.00489949973 222410.06043731095 210385.52287058634 223394.87429245334 203379.75820018395 157094.86908217115 1.7083974878434782 1.52538948699338 1.5074990018931262 1.3252577044975362 1.1596687146046025 1.4157690937759118 1.3392259346200581 1.4220380054271717 1.2946301772198727 1.0 17.261276535587122 -1.5228787452803376 0.11348141182444982 0.9680047396850744 2.9436910574036976 0.6574132251315274 0.10983490958423532 77.55682549703573 0.6135104916686834 1.0186382095378126 24.057520312676214 0.029999999999999995 1.5228787452803376 1.9756863177186232 LSST(ph)SSEETQLFHIPR ddPTM_PC-9_Lapatinib_30min_R1 1 LSSTSSEETQLFHIPR 16 0 Q8N271-3;Q8N271-2;Q8N271 Q8N271-3 PROM2 Prominin-2 1 LS(0.042)S(0.248)T(0.49)S(0.215)S(0.005)EETQLFHIPR 264.01 1.4941999999999996e-68 2179600.0 8445.4 7770.9 8732.4 6410.1 8474.1 10032.0 7740.2 5177.1 9861.7 7396.7 True False 8324.967047303322 7752.90695849267 8014.455780038796 6881.5201374667495 7975.670098721614 9602.954745734205 8140.94968291053 5417.646965932747 8750.971497695202 8675.209739516775 0.9596271787392011 0.8936852469603255 0.923834238097074 0.793239626947632 0.9193633742814699 1.1069420837160195 0.9384153152894256 0.6244975197838294 1.0087331327372204 1.0 13.0826829226415 LSSTS(ph)LASGHSVR ddPTM_PC-9_AZD4547_30min_R2 1 LSSTSLASGHSVR 13 0 Q9BZL6-2;Q9BZL6;Q9BZL6-3;M0QZ82 Q9BZL6-2 PRKD2 Serine/threonine-protein kinase D2 1 LS(0.136)S(0.337)T(0.079)S(0.447)LASGHSVR 81.327 0.006664100000000001 3018800.0 2301.5 2090.1 11221.0 11347.0 11872.0 11381.0 8858.2 14446.0 9647.1 7791.5 True False 3033.329125826125 2765.683950866818 11072.20220832885 8731.124459402427 10223.777725636799 10669.344270857631 9646.562639392763 12213.702636055743 10157.026011055006 7518.721956548028 0.40343679994502385 0.36783963642360706 1.4726175901060032 1.161251142130415 1.359776007773894 1.419036949699375 1.283005635152076 1.6244386621344433 1.3508979411333715 1.0 12.876271735973306 -5.257728671859613 24.95566838857933 1.352163588372033 0.38563809763090195 0.8471668956956452 0.16095269651998637 97.98754275306551 658989.6390619058 0.03959542688400301 0.09669861461592014 5.5242246081187285e-06 5.257728671859613 -0.9665254907411311 LSSTS(ph)LASGHSVR ddPTM_PC-9_Lapatinib_30min_R1 2 LSSTSLASGHSVR 13 0 Q9BZL6-2;Q9BZL6;Q9BZL6-3;M0QZ82 Q9BZL6-2 PRKD2 Serine/threonine-protein kinase D2 1 LS(0.01)S(0.01)T(0.056)S(0.924)LAS(0.001)GHSVR;LS(0.022)S(0.048)T(0.011)S(0.919)LASGHSVR 87.824 0.0039146 4123900.0 32243.0 25805.0 28769.0 22993.0 30302.0 29183.0 23443.0 25257.9 29246.0 20583.7 True False 31783.208907357945 25745.250107954464 26403.72387155147 24683.981922399493 28519.695936024164 27934.91111889564 24656.76383252005 26431.474242497265 25952.00750596689 24141.56511894379 1.316534729656686 1.0664283769966625 1.0937038978816072 1.0224681705922236 1.1813524017813108 1.1571292491295533 1.0213407337526756 1.0948533830458487 1.074992751219864 1.0 14.559231589865387 -4.758708527786294 24.99245274223706 1.084614200315429 1.3165350406514726 0.6251367164957675 0.055002457385872346 50.38575341228666 461035.7567585459 0.013656074507765412 0.09161128669259407 1.7429762612824888e-05 4.758708527786294 0.23192084033604354 LSSWDQAET(ph)PGHTPSLR ddPTM_PC-9_AZD4547_30min_R2 1 LSSWDQAETPGHTPSLR 17 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 LSSWDQAET(0.999)PGHTPSLR 77.1 0.016561000000000003 19118000.0 33748.0 41682.0 43294.0 51908.0 54084.0 61067.0 36369.0 71299.0 62778.0 44393.0 True False 44479.161997992676 55154.89136406425 42719.89327220294 39941.412570605506 46575.37015779492 57248.470836346816 39605.77054391137 60281.377838027045 66096.31691617286 42838.81458217755 1.0382911486187008 1.2874980762658783 0.9972239822428681 0.9323650283082888 1.087223598786786 1.3363691641496587 0.9245300303054782 1.4071672716897778 1.5429072340314303 1.0 15.386630938534081 -7.778443502071212 24.9930519878193 1.3562780484100103 1.0942762531510022 0.2449661663710082 0.18108843643835526 309.654150805615 455130.3024162449 0.09583563757054096 0.04622290419674264 1.6655454866506018e-08 7.778443502071212 -0.26200179525900813 LSSWDQAET(ph)PGHTPSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSSWDQAETPGHTPSLR 17 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 LSSWDQAET(0.997)PGHT(0.001)PS(0.002)LR;LSSWDQAET(0.999)PGHT(0.001)PSLR 91.964 0.0044597000000000005 24339000.0 63368.0 83274.0 87829.0 80005.0 81386.0 54582.0 77954.0 46647.0 53564.0 50632.0 True False 74094.95082495012 91540.89238130674 89923.17645333729 75522.57922970947 65438.997534289476 51719.62383388052 70569.63278191391 45422.565676581915 54347.2721668678 59811.18079730852 1.2388143794727484 1.5304979965455896 1.5034509477094924 1.2626833013988574 1.0940930552107442 0.864714977106887 1.1798735928833144 0.7594326858470233 0.9086473706486898 1.0 15.868127579241413 -6.248148644563761 1.9615538107692407 0.9418854265764287 1.432893844449806 0.7330467220874786 0.1272429005268105 0.16704209374910392 1.2629817475867566 0.0434114640068226 0.05723100818359444 5.647436487526391e-07 6.248148644563761 0.49100841787337735 LSSWDQAETPGHT(ph)PSLR ddPTM_PC-9_AZD4547_30min_R2 3 LSSWDQAETPGHTPSLR 17 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 LSSWDQAETPGHT(0.661)PS(0.339)LR;LSSWDQAETPGHT(0.751)PS(0.249)LR;LSSWDQAETPGHT(0.651)PS(0.349)LR 124.94 8.281e-05 31196400.0 116027.0 126057.0 228094.0 239321.0 224187.0 269603.0 195259.0 272609.0 241629.0 240337.0 True False 152921.17248847618 166802.4600710103 225069.32452602807 184149.24092259147 193062.50479930395 252744.6817903548 212636.67273319542 230483.5429816223 254401.01564461962 231922.87478288924 0.6593621807750994 0.7192152142265383 0.9704490112789564 0.794010686073893 0.8324427031185958 1.089779013937101 0.9168421740729616 0.9937939204892388 1.0969207581734786 1.0 17.823285595879568 -3.7523299549964206 0.3330875422930285 1.0413176008016147 7.60230681724517e-22 0.6650481653683762 0.08280277532585328 8.540374092188292 0.44668524910212387 0.0805527053899283 4.090567411313402 0.00017687646297401887 3.7523299549964206 -1.0413176008016147 LSSWDQAETPGHT(ph)PSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSSWDQAETPGHTPSLR 17 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 LSSWDQAETPGHT(0.683)PS(0.317)LR;LSSWDQAETPGHT(0.714)PS(0.286)LR 103.58 0.0017849 8584800.0 20334.7 34050.0 31945.0 27567.0 36005.0 28085.0 36169.0 27741.0 28588.0 24814.0 True False 23776.963081367783 37430.25897138951 32706.68995208714 26022.510363419857 28950.07871405512 26612.173159183145 32742.810479116535 27012.828144019113 29006.045416817553 29312.58177248409 0.8111521279810082 1.2769349101321923 1.1157901479285295 0.8877590710159606 0.9876331924208309 0.9078754428981812 1.1170224012765886 0.921543805103385 0.9895424989157972 1.0 14.839232421828815 -5.741776631531398 24.982220924565578 0.9736751552300111 1.0888566827401072 0.10543990451718732 0.12220293046191243 446.3169574092813 567056.9494216793 0.03171363294573332 0.05483238821073751 1.8122719495606363e-06 5.741776631531398 0.11518152751009603 LSSWDQAETPGHT(ph)PSLR ddPTM_PC-9_Lapatinib_30min_R1 1 LSSWDQAETPGHTPSLR 17 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 LSSWDQAETPGHT(0.978)PS(0.022)LR 119.18 0.00021503 4958700.0 17694.0 16351.0 25003.0 22228.0 30144.0 26309.0 23612.0 22300.0 23934.0 24505.0 True False 17441.680315317797 16313.140264102445 22947.349854371074 23862.721270434286 28370.98918538423 25183.82539927444 24834.513825596703 23336.139410152446 21238.300883806733 28740.65659913995 0.6068643649512074 0.5675980368726373 0.7984281700459746 0.8302775264761475 0.9871378229484575 0.8762439129531944 0.8640899952974582 0.811955681306556 0.7389636632185459 1.0 14.810805401035111 -5.383503608314284 2.781598763787104 0.8684919174597278 0.5814193234274069 0.6970451661224608 0.07392271397361623 0.15380347963076993 2.261987472810799 0.02089935063614404 0.05385365826534102 4.135198786238154e-06 5.383503608314284 -0.2870725940323209 LSSWDQAETPGHTPS(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 2 LSSWDQAETPGHTPSLR 17 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 LSSWDQAETPGHT(0.367)PS(0.632)LR;LSSWDQAETPGHT(0.289)PS(0.711)LR 131.56 1.4641e-05 3558400.0 25205.0 45916.0 50411.0 41376.0 41433.0 46289.0 45972.0 53281.0 51275.0 39758.0 True False 24845.57207796909 45809.68432307063 46266.40217208736 44418.92906628981 38995.99240041214 44309.32737492928 48352.20521727641 55756.62977185345 45499.869550312986 46630.117325795 0.5328224225639023 0.9824055127935413 0.992199994883855 0.9525802552874557 0.8362833858631579 0.9502298067437652 1.0369308076033679 1.195721412886298 0.9757614211522307 1.0 15.508974439189291 -4.761388976670207 6.9742035407571565 0.9922029421137255 0.5228492643000252 0.7261475550146483 0.08449503061170258 0.06440144273390426 17.923887327010124 0.0234849849714515 0.1431147102784161 1.7322518081544697e-05 4.761388976670207 -0.4693536778137003 LST(ph)GSFPEDLLESDSSR ddPTM_PC-9_AZD4547_30min_R2 1 LSTGSFPEDLLESDSSR 17 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 LS(0.303)T(0.575)GS(0.122)FPEDLLESDSSR 105.17 0.0035467 0.0 1253.9 1218.8 1188.2 2438.4 1192.2 2072.4 2690.2 2131.3 3044.8 1812.2 True False 1652.6141172597781 1612.7532650669718 1172.4436916439117 1876.2645529044567 1026.6836088699629 1942.8125003888383 2929.622588392046 1801.9565574017452 3205.741911917603 1748.7554295907516 0.9450230085327181 0.9222291681143729 0.670444632682736 1.0729142115335961 0.5870938791653846 1.1109686737861912 1.6752614681388833 1.0304222802747458 1.833156230810285 1.0 10.772112821383919 -7.001064095552204 21.084174182318744 1.3880839061001395 0.84783788200675 0.4771316507177893 0.2691069396589451 4.3246469999995565 85702.33125767075 0.08774710408982798 0.0760372037093539 9.975528286618191e-08 7.001064095552204 -0.5402460240933895 LST(ph)IQNSPTK ddPTM_PC-9_AZD4547_30min_R2 1 LSTIQNSPTK 10 0 Q5VYV7 Q5VYV7 SLX4IP Protein SLX4IP 1 LS(0.001)T(0.469)IQNS(0.142)PT(0.388)K 130.56 0.00051079 19126000.0 30781.0 26638.0 35137.0 50133.0 42450.0 37125.0 33856.0 36773.0 28355.0 40263.0 True False 40568.71771542646 35248.21256551853 34671.060421892056 38575.611397128894 36556.550240337136 34803.567881169474 36869.118412237425 31090.577809475166 29853.787412120208 38853.404625103394 1.0441483341517719 0.9072103952183503 0.8923557859712221 0.9928502217333351 0.9408840896459754 0.895766232508816 0.9489288974283631 0.8002021472627234 0.7683699202213933 1.0 15.245753403421576 -7.750660125341534 24.976681798919742 0.8382145258507046 0.9421345758456562 0.236020107252217 0.07167427487829849 241.08613367340084 558625.4290661919 0.03273487201499359 0.01865790937571663 1.7755784878482378e-08 7.750660125341534 0.10392004999495164 LSTASCPT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 LSTASCPTPK 10 0 H0YJ30;G3V582;F5H039;Q9NQX3;Q9NQX3-2 H0YJ30 GPHN Gephyrin;Molybdopterin adenylyltransferase;Molybdopterin molybdenumtransferase 1 LSTAS(0.006)CPT(0.994)PK;LSTAS(0.02)CPT(0.98)PK 146.16 0.00034528 12018700.0 54957.0 64275.0 62726.0 87683.0 76608.0 90959.0 96800.0 97439.0 95052.0 88302.0 True False 72432.18282338753 85050.63678386898 61894.2122555597 67469.0390388458 65972.30155033557 85271.31935093057 105415.01247355208 82382.04147546984 100076.25466749599 85210.573857037 0.8500374958735923 0.9981230372484481 0.726367743508023 0.7917918632028315 0.7742267017356478 1.0007128868066948 1.2371118712381084 0.966805382788376 1.174458170360407 1.0 16.37874484643926 -6.929653555248839 4.877483914056517 1.095601844051075 0.8313695699767578 0.6234006857304262 0.0982604088546108 0.13659251424653152 6.173462788391116 0.03533393519918225 0.030824308258950366 1.1758351664029948e-07 6.929653555248839 -0.26423227407431726 LSTASCPT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LSTASCPTPK 10 0 H0YJ30;G3V582;F5H039;Q9NQX3;Q9NQX3-2 H0YJ30 GPHN Gephyrin;Molybdopterin adenylyltransferase;Molybdopterin molybdenumtransferase 1 LSTAS(0.012)CPT(0.988)PK;LSTAS(0.001)CPT(0.999)PK;LSTAS(0.01)CPT(0.99)PK 112.94 0.002873 5151500.0 91599.0 99510.0 79331.0 105499.0 100302.0 82517.0 80578.0 92112.0 71011.0 57758.0 True False 107104.9015372839 109388.69516132076 81222.551904493 99588.23306237307 80648.5431239316 78189.66325712351 72945.06850579915 89694.15760073115 72049.4015353866 68229.06818792348 1.5697840287410145 1.6032564721539393 1.1904391201823472 1.459615904295761 1.1820261549197937 1.1459875582906327 1.0691201044236216 1.3146032912788188 1.055992752780102 1.0 16.058098892934005 -1.5228787452803487 0.259114505109688 1.0458619455397609 5.002260751975351 0.6985340532272757 0.11334877962397077 27.938372599398697 0.38505945000794023 0.13583770235690446 48.751896745083755 0.02999999999999923 1.5228787452803487 3.9563988064355904 LSTASCPT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 LSTASCPTPK 10 0 H0YJ30;G3V582;F5H039;Q9NQX3;Q9NQX3-2 H0YJ30 GPHN Gephyrin;Molybdopterin adenylyltransferase;Molybdopterin molybdenumtransferase 1 LSTASCPT(1)PK;LSTAS(0.002)CPT(0.998)PK 124.6 0.00099605 11834100.0 92311.0 94043.0 94882.0 87480.0 81160.0 67852.0 69688.0 62707.0 73598.0 49371.0 True False 90994.62821223568 93825.24921148487 87081.16821511157 93913.57102472537 76386.32836669925 64950.12813073727 73296.10365399723 65620.59614315823 65308.618218701755 57904.711567277685 1.5714546493597823 1.6203387716122586 1.5038701663151308 1.6218640674103024 1.3191729360044968 1.121672595765782 1.2658055220400635 1.1332514119669812 1.1278636306273921 1.0 15.821393121169775 -6.4665201572969275 2.878349239834337 1.1465841120115743 1.5778407538618116 0.9015138430387559 0.0697580460487926 0.07829623327496321 1.284153781435786 0.02303198393685165 0.025446466246648033 3.4157009672075445e-07 6.4665201572969275 0.43125664185023727 LSTEADTDT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 LSTEADTDTPK 11 0 Q9BYW2;H7C3H4;A0A1W2PPX9 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 LSTEADT(0.227)DT(0.773)PK 128.57 0.00074206 3191100.0 22046.0 22950.0 19263.0 22061.0 20278.0 20515.0 18251.0 19415.0 18405.0 16169.0 True False 21731.619997258746 22896.860685043797 17679.270497330323 23683.439533338627 19085.2879080819 19637.62127280075 19195.947477171154 20317.091777942143 16332.03508675787 18963.790106161774 1.1459534130889606 1.2073989722974248 0.932264615794599 1.2488769070294303 1.0064068311893333 1.035532515539709 1.0122421398733972 1.071362405099635 0.8612220972352576 1.0 14.210959709867542 -6.4521081645670835 0.45502068078953317 0.959553797472565 1.1721129734306022 0.3174477996047921 0.0940085016176372 1.7196858919860165 0.7015333014675414 0.08342710289381701 0.16358418673685865 3.530952176088162e-07 6.4521081645670835 0.2125591759580372 LSTGS(ph)FPEDLLESDSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSTGSFPEDLLESDSSR 17 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 LS(0.004)T(0.03)GS(0.965)FPEDLLESDSSR 88.992 0.0026314 2185600.0 9462.7 8733.5 8058.6 6887.8 9992.4 7313.0 8046.6 4905.1 5161.6 5921.0 True False 11064.548213155782 9600.504162309257 8250.74758641069 6501.898896548894 8034.460951043591 6929.493406199262 7284.367795660903 4776.346322383049 5237.078635212172 6994.430429389792 1.5819083948085069 1.3725927020403323 1.1796167922039795 0.9295823244203936 1.1486940977043263 0.9907158954762532 1.0414526056407434 0.6828785232194734 0.748749835755971 1.0 12.771990865261422 -1.5228810782233968 0.3521807324843541 0.8356298173596766 10.145870292707135 0.77690572465563 0.12102558630989507 28.90754850619719 0.4062395797093511 0.1070019872348959 179.0878978657672 0.029999838846435513 1.5228810782233968 9.31024047534746 LSTGSFPEDLLESDSS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 LSTGSFPEDLLESDSSR 17 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 LS(0.014)T(0.011)GS(0.389)FPEDLLES(0.02)DS(0.128)S(0.438)R 65.038 0.022026 2521100.0 3301.9 3440.9 1592.5 4850.1 3616.6 3810.4 3842.5 5095.8 1151.1 2677.8 True False 4351.835516213465 4553.103634533101 1571.3824094789857 3731.984378298026 3114.4975170601456 3572.135085640621 4184.475056091158 4308.361199834758 1211.9447959827748 2584.051037058886 1.684113608362254 1.7620022086387856 0.6081081166521777 1.4442378748624465 1.2052770910457724 1.3823779153009115 1.6193469076577691 1.6672895148148648 0.4690096203990559 1.0 11.335418849347414 -1.522879592668669 0.038130005759620285 6.679445773763827e-07 3.3888423201265128 0.12704885436578717 0.40631492403163133 2243.3507847368187 6.547396640358711 164.2123710817912 503.787645171267 0.029999941464544915 1.522879592668669 3.3888416521819353 LSTGTT(ph)VEDVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSTGTTVEDVQK 12 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 LS(0.045)T(0.281)GT(0.088)T(0.587)VEDVQK 85.973 0.022922 8007900.0 9862.2 15298.0 18011.0 17798.0 38604.0 37687.0 45272.0 44399.0 52559.0 35485.0 True False 11531.675672671121 16816.684339040155 18440.450547097873 16800.835761894545 31039.823321132742 35710.62737582819 40983.50841910374 43233.57329462902 53327.57594314097 41918.14960089454 0.2750998262677376 0.4011790715752702 0.43991566237228064 0.4008009876832925 0.740486486561667 0.8519132575228492 0.9777031860735843 1.0313807671917468 1.272183444423867 1.0 15.355287412728876 -6.649314595949641 0.8784768394357029 1.1215409909999912 0.3269774449355903 0.9359558553648638 0.08164301333349999 0.13061247427032438 0.22109418859547744 0.04790843476689664 0.050376362506777 2.242257080321344e-07 6.649314595949641 -0.7945635460644009 down LSTIQNS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSTIQNSPTK 10 0 Q5VYV7 Q5VYV7 SLX4IP Protein SLX4IP 1 LS(0.06)T(0.331)IQNS(0.586)PT(0.022)K 122.52 0.0005319 18599000.0 45773.0 50938.0 42898.0 62394.0 60639.0 55176.0 57159.0 53630.0 49916.0 35912.0 True False 53521.4648420408 55994.788002485744 43920.851011570965 58898.26646407731 48757.22325070376 52282.47342820327 51744.485724676444 52222.26932568201 50645.92706820573 42422.5613207644 1.261627378822218 1.3199294493111664 1.0353182279466282 1.3883712965546144 1.149322948278438 1.2324214238948552 1.219739782646016 1.2310022709571993 1.1938441596032598 1.0 15.372544107754342 -13.689834278746842 0.286804202647462 1.923756069379347e-07 1.2400429842026377 0.37572090999924246 0.08858193688494152 147.48776945781262 2.190144416277799 86.96619355804864 0.0915988049122466 2.0425171945793078e-14 13.689834278746842 1.2400427918270307 LSTIQNS(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 2 LSTIQNSPTK 10 0 Q5VYV7 Q5VYV7 SLX4IP Protein SLX4IP 1 LST(0.19)IQNS(0.79)PT(0.02)K;LS(0.116)T(0.116)IQNS(0.61)PT(0.158)K 156.0 0.00016796 45404000.0 186878.0 160400.0 154250.0 140249.0 167329.0 162675.0 149490.0 149181.0 150924.0 131581.0 True False 184213.0854507724 160028.6036549468 141568.16042221867 150563.3793169487 157487.03720147142 155717.76946394664 157229.86073981234 156112.49387201542 133925.34981982323 154324.60052933858 1.193672848132542 1.0369610749423184 0.9173402032899169 0.9756278571304331 1.0204921098858224 1.0090275233490282 1.0188256454285876 1.0115852776326282 0.8678159500199888 1.0 17.23560853137304 -4.813298778287262 3.388327851650158 0.9817316145112356 1.213552635163581 0.6548731377582502 0.04718157127447443 0.1747546493573324 3.283203347266855 0.01208028440161458 0.10092877361724893 1.5370968116133433e-05 4.813298778287262 0.23182102065234544 LSTIQNSPT(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 LSTIQNSPTK 10 0 Q5VYV7 Q5VYV7 SLX4IP Protein SLX4IP 1 LS(0.001)TIQNS(0.387)PT(0.613)K 92.925 0.017412 9709100.0 53096.0 51400.0 62940.0 82759.0 73410.0 68921.0 60816.0 77399.0 57541.0 73578.0 True False 69979.4235345921 68014.04481821653 62105.37447573455 63680.19116380414 63218.28864883743 64611.35897476304 66228.50618379698 65438.76300208211 60582.499787720306 71002.05661540013 0.9855971343710878 0.9579165458069913 0.8746982472936436 0.896878121555596 0.8903726407711628 0.9099927812619026 0.9327688427750729 0.9216460215588832 0.8532499293066976 1.0 16.115573193263486 -4.959706254874488 0.0009495257808305403 1.8326370231971438 8.438840638338707e-06 0.0037583483002573415 0.044941205167976284 6069967.171340272 1099.875752698392 1055626.9636096396 1067202.8963265389 1.0972200754168104e-05 4.959706254874488 -1.8326285843565056 LSTIQNSPT(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSTIQNSPTK 10 0 Q5VYV7 Q5VYV7 SLX4IP Protein SLX4IP 1 LST(0.002)IQNS(0.18)PT(0.819)K 120.57 0.0016985 14867000.0 46225.0 36300.0 38179.0 48684.0 59703.0 44346.0 43924.0 50674.0 42611.0 38791.0 True False 54049.979514633895 39903.624101657566 39089.332154663774 45956.393315657595 48004.625731571505 42020.41769332869 39763.200737778614 49343.86119354111 43234.105262907986 45823.50123061295 1.1795253104432175 0.8708113310861428 0.8530411492989468 1.0029000857960602 1.0475983816684316 0.917005828119839 0.867746891222147 1.0768243339855563 0.943491965952722 1.0 15.483800074225732 -7.777134613445137 24.998943432044104 1.007618535534801 0.9579708880525374 0.03912201082886846 0.09824629795497182 909.5046061992151 1448613.1005677497 0.053365438515095044 0.02577563387734821 1.670572725148222e-08 7.777134613445137 -0.04964764748226369 LSTTPSPT(ph)SSLHEDGVEDFRR ddPTM_PC-9_AZD4547_30min_R2 1 LSTTPSPTSSLHEDGVEDFRR 21 1 C9J919;C9JNL1;O94842-3;O94842-2;O94842 C9J919 TOX4 TOX high mobility group box family member 4 1 LST(0.001)T(0.004)PS(0.014)PT(0.797)S(0.176)S(0.008)LHEDGVEDFRR 74.214 0.0041664 4323400.0 4010.6 3283.1 9900.1 14308.0 9203.6 7975.7 5940.6 9710.8 6874.3 7972.1 True False 5285.887374337717 4344.297870480286 9768.818205389574 11009.51165639639 7925.839005700046 7476.978218177599 6469.30189153289 8210.218991984642 7237.661463838406 7692.99920551839 0.6871035903066273 0.5647079577707492 1.2698322129530633 1.431107863432376 1.0302664531688284 0.9719197959638637 0.840933648724712 1.0672325282570205 0.9408114144411508 1.0 12.909330444014929 -5.2503580902020754 24.969376879781787 1.0713490022375602 0.6259057149978078 0.5441602355980923 0.16221137204536798 593.2866469267412 1336841.6997044433 0.04628890921329393 0.12001817951470044 5.618778472225257e-06 5.2503580902020754 -0.44544328723975246 LSVAS(ph)TPISQR ddPTM_PC-9_AZD4547_30min_R2 2 LSVASTPISQR 11 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6;Q9BXS6-7;H0YMD2 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 LS(0.068)VAS(0.525)T(0.359)PIS(0.048)QR;LS(0.052)VAS(0.473)T(0.473)PIS(0.002)QR 126.34 0.00041543 32365000.0 187826.0 194205.0 210601.0 314440.0 308850.0 277300.0 235470.0 367720.0 270010.0 318900.0 True False 247550.7609765013 256977.9683642361 207808.2931357512 241950.71604957228 265971.50863906095 259960.38716358974 256426.3738341671 310897.3233649741 284282.17736366007 307735.40806560504 0.8044272920447517 0.8350614249415584 0.6752823616951134 0.7862296950827045 0.8642863371197097 0.8447529284903403 0.8332689937958015 1.0102747854699092 0.9237876757524599 1.0 18.23133092428875 -7.446050742825153 0.8030654736031696 0.9949969706492771 0.7770899976022433 0.6753908446645589 0.054182249225160045 0.38647704823230256 0.4709288497089647 0.047566211578064434 0.025345743668277985 3.5805459967628674e-08 7.446050742825153 -0.21790697304703377 LSVAS(ph)TPISQR ddPTM_PC-9_Lapatinib_30min_R1 1 LSVASTPISQR 11 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6;Q9BXS6-7;H0YMD2 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 LSVAS(0.498)T(0.498)PIS(0.004)QR 104.94 0.0026206999999999997 12534000.0 71660.0 108070.0 110310.0 109300.0 118340.0 90493.0 75057.0 76948.0 91141.0 59392.0 True False 70638.11525916558 107819.77055480113 101240.73760891402 117338.28661411152 111379.47386539177 86622.8253394862 78943.08420327849 80523.2849924849 80875.74082272215 69657.82806513463 1.0140728934745757 1.5478485842823377 1.453400722087506 1.6844953377586298 1.5989512874453202 1.2435476061425312 1.1332981000995543 1.15598328614539 1.1610431026804056 1.0 16.087997869865568 -6.939882637528812 4.817765663804827 1.132411401990528 1.475717788295555 0.4736404074085526 0.1724424207857786 0.18746234386753122 8.836650839960576 0.06388914132848482 0.05550338123991701 1.1484639371025862e-07 6.939882637528812 0.34330638630502697 LSVAST(ph)PISQR ddPTM_PC-9_Lapatinib_30min_R1 1 LSVASTPISQR 11 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6;Q9BXS6-7;H0YMD2 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 LS(0.098)VAS(0.201)T(0.637)PIS(0.064)QR 89.74700000000001 0.022285 11055000.0 88818.0 123910.0 136370.0 120260.0 113720.0 103600.0 88803.0 79009.0 105100.0 60545.0 True False 87551.4390327736 123623.09400800752 125158.18500342312 129104.3215755998 107031.21318212217 99169.26950339544 93400.7848235838 82680.0465765353 93262.53124793559 71010.12257885867 1.2329430770316634 1.7409221322033448 1.7625400500390849 1.8181115154705716 1.5072669824398781 1.396551166254716 1.3153164849118475 1.164341696280229 1.3133695290324983 1.0 16.11573707674954 -7.026117255752833 1.365012297299842 1.1816622720062144 1.6516734313382175 0.5786215289688322 0.16999441679257465 0.31584161143404393 1.1930401003018911 0.09312879754679611 0.06659909949229081 9.416353288070851e-08 7.026117255752833 0.4700111593320031 LSVGEQPDVTHDPYEFLQS(ph)PEPAASAK ddPTM_PC-9_AZD4547_30min_R2 4 LSVGEQPDVTHDPYEFLQSPEPAASAK 27 0 Q9H8M2-2;Q9H8M2-3;Q9H8M2-1;Q9H8M2-6;Q9H8M2 Q9H8M2-2 BRD9 Bromodomain-containing protein 9 1 LSVGEQPDVTHDPYEFLQS(1)PEPAASAK;LSVGEQPDVTHDPY(0.001)EFLQS(0.999)PEPAASAK;LSVGEQPDVTHDPYEFLQS(1)PEPAASAK;LSVGEQPDVTHDPYEFLQS(0.999)PEPAASAK 164.68 1.9497e-13 100957000.0 141046.0 123968.0 189989.0 224009.0 189402.0 181255.0 165256.0 211651.0 162345.0 189037.0 True False 185895.69406094827 164038.2316736316 187469.62172339243 172367.18595454996 163106.80161649775 169921.09619666953 179963.46385670814 178945.2012061358 170926.22526611382 182418.8721683847 1.0190595515213703 0.899239369938728 1.0276876481855757 0.9448977723940954 0.8941333737988434 0.9314885799744509 0.9865397243032505 0.9809577215287107 0.9369985859157028 1.0 17.47689546586554 -7.272403415184248 24.748008396091592 0.9745371509121875 0.9507035018918069 0.06263703346698546 0.04369616786380441 2083.73668797033 4703388.1968330145 0.018131470064138053 0.012358317190379471 5.3406803429849444e-08 7.272403415184248 -0.023833649020380654 LSVGEQPDVTHDPYEFLQS(ph)PEPAASAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LSVGEQPDVTHDPYEFLQSPEPAASAK 27 0 Q9H8M2-2;Q9H8M2-3;Q9H8M2-1;Q9H8M2-6;Q9H8M2 Q9H8M2-2 BRD9 Bromodomain-containing protein 9 1 LSVGEQPDVTHDPY(0.01)EFLQS(0.99)PEPAASAK;LSVGEQPDVTHDPY(0.023)EFLQS(0.977)PEPAASAK;LSVGEQPDVTHDPY(0.1)EFLQS(0.9)PEPAASAK;LSVGEQPDVTHDPY(0.002)EFLQS(0.997)PEPAAS(0.001)AK;LSVGEQPDVTHDPY(0.001)EFLQS(0.998)PEPAAS(0.001)AK 134.98 4.9685e-12 81574000.0 163869.1 152439.9 179878.1 201623.8 219667.8 199784.7 198683.1 194063.1 184503.1 149883.8 True False 191608.9020677449 167573.12583179798 184167.07609549284 190327.47215917887 176625.47148849696 189307.63863113607 179862.3984269224 188969.14925185087 187201.10879192743 177056.54646049175 1.0821904408403242 0.9464384637660946 1.0401596539475468 1.0749530359875645 0.997565325989847 1.0691931047767163 1.015847208264941 1.0672813461546722 1.0572956071618584 1.0 17.43385066112799 -5.479681229812243 24.997741144621312 1.0427464571114673 1.0090606038886527 0.056477982015241346 0.040511722653370705 994.3089511772324 575389.5587122649 0.009783953681781116 0.020363300328219664 3.313742594500168e-06 5.479681229812243 -0.03368585322281459 LSVGEQPDVTHDPYEFLQS(ph)PEPAASAK ddPTM_PC-9_Lapatinib_30min_R1 4 LSVGEQPDVTHDPYEFLQSPEPAASAK 27 0 Q9H8M2-2;Q9H8M2-3;Q9H8M2-1;Q9H8M2-6;Q9H8M2 Q9H8M2-2 BRD9 Bromodomain-containing protein 9 1 LSVGEQPDVTHDPY(0.004)EFLQS(0.994)PEPAAS(0.002)AK;LSVGEQPDVTHDPY(0.004)EFLQS(0.996)PEPAASAK;LSVGEQPDVT(0.001)HDPY(0.197)EFLQS(0.8)PEPAAS(0.002)AK;LSVGEQPDVTHDPYEFLQS(1)PEPAASAK 146.38 2.0582e-12 72174800.0 156448.0 178510.0 209168.0 179363.0 212668.0 203141.0 179556.0 179635.0 207508.0 174599.0 True False 154217.02283095068 178096.67106262172 191971.01445182934 192553.95335742785 200159.28636137492 194453.13297479993 188852.5311057443 187981.4978898084 184136.26388388753 204778.20451145608 0.7530929534169404 0.8697052085572824 0.9374582363871139 0.9403049207156011 0.9774442882673935 0.949579245695171 0.9222296462472361 0.9179761016963698 0.8991985466577633 1.0 17.643702645260298 -4.793052277748055 1.8390063726674057 0.9414949939875551 0.6942041168339644 0.8202284329831835 0.027481986433844228 0.340677017273138 1.2243148299393036 0.007712183068546953 0.1466120600678358 1.610451767048156e-05 4.793052277748055 -0.24729087715359066 LSVGSVTSRPSTPT(ph)LGTPTPQTMSVSTK ddPTM_PC-9_Lapatinib_30min_R1 1 LSVGSVTSRPSTPTLGTPTPQTMSVSTK 28 1 Q16594;D6RIE8 Q16594 TAF9 Transcription initiation factor TFIID subunit 9 1 LS(0.002)VGS(0.043)VT(0.109)S(0.109)RPS(0.109)T(0.109)PT(0.422)LGT(0.078)PT(0.016)PQT(0.001)MS(0.001)VSTK 45.328 0.022962 4524400.0 10241.0 8323.9 8718.5 6702.7 8763.8 8199.7 9865.8 8258.4 8571.5 9337.4 True False 10094.961462030607 8304.626520968888 8001.69858438324 7195.638917551735 8248.330514293732 7849.0179454342815 10376.60285026986 8642.115412771427 7606.087408103514 10951.35714869657 0.9218000403933597 0.7583193944101535 0.73065817101359 0.6570545385243106 0.7531788437084665 0.7167164616093696 0.9475175276796521 0.7891364782857083 0.694533773744087 1.0 13.41882204666992 -7.22132882020378 24.992054068574372 0.840225151235466 0.7505633273886176 0.188117609605147 0.10027483895871055 999.8705442704633 622999.1548188367 0.03851319710751166 0.029831812819912897 6.007187391737384e-08 7.22132882020378 -0.0896618238468484 LSVPT(ph)SDEEDEVPAPK ddPTM_PC-9_Lapatinib_30min_R1 1 LSVPTSDEEDEVPAPK 16 0 Q5STZ8;Q8NE71-2;Q8NE71;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 LSVPT(0.5)S(0.5)DEEDEVPAPK 105.14 0.0039217 0.0 11215.0 18827.0 15339.0 15595.0 19572.0 16821.0 16028.0 18745.0 14474.0 14471.0 True False 11055.072043420887 18783.407238227435 14077.886630252291 16741.908323394957 18420.813440032514 16101.60504166617 16857.851414393695 19615.96113198688 12843.785702023013 16972.29306860455 0.6513599546469431 1.1067100457376082 0.8294628529773416 0.9864258327216986 1.085346179539372 0.9486994465969371 0.9932571483565441 1.1557637528821962 0.7567501721839535 1.0 14.050893875202826 -4.748482580390658 24.987460476758127 0.9870687914845024 0.6513591507657274 0.43095000972245867 0.11488904935012711 579.6188309374019 1117740.5656067056 0.026792911638477343 0.48627255171548645 1.7845035637798284e-05 4.748482580390658 -0.33570964071877507 LSVPT(ph)SDEEDEVPAPKPR ddPTM_PC-9_AZD4547_30min_R2 3 LSVPTSDEEDEVPAPKPR 18 1 Q5STZ8;Q8NE71-2;Q8NE71;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 LS(0.003)VPT(0.579)S(0.418)DEEDEVPAPKPR;LSVPT(0.5)S(0.5)DEEDEVPAPKPR;LS(0.047)VPT(0.594)S(0.359)DEEDEVPAPKPR 199.33 1.2465e-53 198780000.0 62888.0 60569.0 79037.0 92210.0 82607.0 78625.0 62657.0 79815.0 71905.0 75448.0 True False 82885.0758483394 80146.74475864893 77988.91773814156 70952.40913029849 71138.44395061307 73708.56632072585 68233.35161730745 67481.42571623919 75705.75150303304 72806.58848458379 1.1384282325752655 1.1008171983723611 1.0711793995766619 0.9745328081856506 0.9770880002937656 1.012388684251193 0.9371864969576937 0.9268587791409543 1.0398200640737771 1.0 16.151781389643027 -5.564869806373262 2.018404084789782 0.976003149276681 1.124441918790229 0.7503602575672927 0.032923839989505356 0.15904756190219282 1.2827288360322462 0.009759001194133685 0.023924163886923446 2.72351764701613e-06 5.564869806373262 0.14843876951354806 LSVPT(ph)SDEEDEVPAPKPR ddPTM_PC-9_Lapatinib_30min_R1 1 LSVPTSDEEDEVPAPKPR 18 1 Q5STZ8;Q8NE71-2;Q8NE71;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 LSVPT(0.627)S(0.373)DEEDEVPAPKPR 103.2 0.0023589 0.0 16128.0 17594.0 17594.0 14436.0 13601.0 12105.0 12677.0 16663.0 17016.0 12974.0 True False 15898.011762487022 17553.262173972147 16147.489234804021 15497.671597084278 12801.015920594833 11587.297368133226 13333.353030962613 17437.223811272208 15099.478893576312 15216.538613231667 1.044785030720638 1.1535647245496794 1.061180183301532 1.0184754884798932 0.8412567566097854 0.7614936394310724 0.876240869876181 1.1459389191251108 0.9923070730715614 1.0 13.893352598216346 -5.922971985316829 3.1847355476186183 0.931638562831445 1.0943631892240953 0.30612190321721855 0.10110946669504926 0.3286851222147877 6.719700680938608 0.03379885276125527 0.052477124335516 1.1940651265741878e-06 5.922971985316829 0.16272462639265028 LSVPTS(ph)DEEDEVPAPK ddPTM_PC-9_AZD4547_30min_R2 1 LSVPTSDEEDEVPAPK 16 0 Q5STZ8;Q8NE71-2;Q8NE71;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 LSVPT(0.074)S(0.926)DEEDEVPAPK 89.46600000000001 0.020085 0.0 14866.0 17770.0 17571.0 14364.0 14857.0 21477.0 16815.0 17170.0 19832.0 16507.0 True False 19593.078767990963 23513.804988710264 17337.997059312558 11052.601721587775 12794.362000487372 20134.039794851895 18311.502425028717 14516.771027348554 20880.279032169572 15929.094954339773 1.230018329613445 1.4761544868752314 1.0884483461873606 0.6938625046350526 0.8032070897412559 1.2639788922450057 1.149563266307222 0.9113368379660238 1.3108264526027502 1.0 13.959376678931298 -5.399603489986214 5.774070485701711 1.0129295414921216 1.3484486330896368 0.3251024442435432 0.1892041120235906 0.26014138880042165 11.083959701888027 0.05239840070641098 0.1110093368718614 3.984708075973916e-06 5.399603489986214 0.33551909159751525 LSVPTS(ph)DEEDEVPAPKPR ddPTM_PC-9_AZD4547_30min_R2 5 LSVPTSDEEDEVPAPKPR 18 1 Q5STZ8;Q8NE71-2;Q8NE71;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 LSVPT(0.225)S(0.775)DEEDEVPAPKPR;LSVPT(0.053)S(0.947)DEEDEVPAPKPR;LSVPT(0.218)S(0.782)DEEDEVPAPKPR;LSVPT(0.043)S(0.957)DEEDEVPAPKPR;LSVPT(0.022)S(0.978)DEEDEVPAPKPR 240.5 4.0519e-43 409609000.0 428385.0 430341.0 520645.0 741654.0 581776.0 478417.0 446463.0 520215.0 407722.0 521572.0 True False 564602.5190384651 569440.3124730771 513740.9071166003 570677.1287400762 501006.444584744 448501.5093604172 486197.34208656463 439827.7251014625 429273.3525390394 503311.92303416185 1.1217745759623963 1.1313864949597605 1.0207207173229047 1.133843850349919 0.9954193843938377 0.891100506136779 0.9659960748705816 0.8738670891204172 0.8528972450150021 1.0 18.941093248902888 -6.499177903973929 3.415345461170416 0.9124760847456848 1.0977392454194432 0.7486747531621512 0.05038318047194709 0.11940276529345614 2.8992635428746363 0.016728915208045887 0.018070407185262406 3.168269350372899e-07 6.499177903973929 0.18526316067375848 LSVPTS(ph)DEEDEVPAPKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 LSVPTSDEEDEVPAPKPR 18 1 Q5STZ8;Q8NE71-2;Q8NE71;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 LSVPT(0.189)S(0.811)DEEDEVPAPKPR;LSVPT(0.192)S(0.807)DEEDEVPAPKPR;LSVPT(0.263)S(0.737)DEEDEVPAPKPR;LSVPT(0.106)S(0.894)DEEDEVPAPKPR;LSVPT(0.179)S(0.821)DEEDEVPAPKPR;LSVPT(0.239)S(0.761)DEEDEVPAPKPR;LSVPT(0.177)S(0.823)DEEDEVPAPKPR 143.23 1.9768e-05 215282600.0 467307.0 465982.0 435933.0 555535.0 562542.0 491146.0 502273.0 512055.0 451795.0 394135.0 True False 546412.845366035 512241.6133922471 446327.29600510857 524410.1750187707 452315.933341536 465389.4391468814 454694.0652983857 498614.0988171192 458401.6471628333 465588.5555290558 1.1735959547913226 1.1002023295228525 0.9586302985861404 1.1263381988048975 0.9714928083392472 0.9995723340279528 0.9766006056177851 1.0709328932076863 0.9845638208223226 1.0 18.82869607073198 -5.012543145971701 3.9611563119677533 1.0147008003019518 1.164990347889688 0.5379393919430964 0.048724261572159415 0.15104812244906832 5.358624403933865 0.012006931597752457 0.046840244579872535 9.715314277862018e-06 5.012543145971701 0.15028954758773616 LSVPTS(ph)DEEDEVPAPKPR ddPTM_PC-9_Lapatinib_30min_R1 5 LSVPTSDEEDEVPAPKPR 18 1 Q5STZ8;Q8NE71-2;Q8NE71;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 LSVPT(0.039)S(0.961)DEEDEVPAPKPR;LSVPT(0.056)S(0.944)DEEDEVPAPKPR;LSVPT(0.173)S(0.827)DEEDEVPAPKPR;LSVPT(0.223)S(0.777)DEEDEVPAPKPR;LSVPT(0.035)S(0.965)DEEDEVPAPKPR 157.0 6.0136e-06 500873000.0 447266.0 410160.0 435191.0 372743.0 382850.0 380397.0 352570.0 381253.0 374089.0 296857.0 True False 440887.9048214611 409210.2997201553 399411.2758658396 400155.7636541961 360331.51571206 364128.30705871765 370824.34946174064 398967.4062125046 331955.15748819173 348168.3369129114 1.2663067202797997 1.1753231306111347 1.1471786303352043 1.14931692870822 1.0349347643355375 1.045839809235147 1.0650720072643949 1.1459037595147539 0.9534329296900564 1.0 18.409425481975568 -1.5228787453028414 0.2877576904313869 1.017308278845044 2.973905018465275 0.715105751192326 0.04772182124486687 29.90876848133414 0.42386411243699496 0.051509914473715744 29.697159748221058 0.02999999999844549 1.5228787453028414 1.9565967396202308 LSVPYVPQVTDEDRLS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 LSVPYVPQVTDEDRLSR 17 1 A0A1B0GUZ7;Q14156-3;Q14156-2;Q14156 A0A1B0GUZ7 EFR3A Protein EFR3 homolog A 1 LSVPYVPQVT(0.003)DEDRLS(0.997)R;LSVPYVPQVT(0.2)DEDRLS(0.8)R 97.689 0.00067441 6640400.0 11203.7 24972.0 25413.0 24846.0 23836.0 18185.800000000003 21873.3 22867.3 16680.4 23731.0 True False 14766.24354856318 33043.7106459242 25076.007015440762 19118.138566873422 20526.782839309206 17048.639051134585 23819.98132580319 19333.68422327825 17562.091890288473 22900.18491315423 0.6448089220485383 1.442945145257031 1.0950132983876784 0.8348464713003981 0.8963588249245226 0.7444760431319302 1.0401654578832948 0.8442588693758833 0.7668973834442939 1.0 14.483071627313308 -5.755079134931344 24.427632526997247 0.8710945076225677 1.0991248318087967 0.1452429064717169 0.19984882223486802 172.0189125645033 660657.2703800421 0.051890423320636266 0.08707975527334538 1.7576033232416388e-06 5.755079134931344 0.22803032418622904 LSVPYVPQVTDEDRLS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSVPYVPQVTDEDRLSR 17 1 A0A1B0GUZ7;Q14156-3;Q14156-2;Q14156 A0A1B0GUZ7 EFR3A Protein EFR3 homolog A 1 LSVPYVPQVT(0.015)DEDRLS(0.985)R;LSVPYVPQVT(0.209)DEDRLS(0.791)R 71.434 0.016468 2960500.0 20204.8 22658.0 16421.9 15530.5 33179.0 18983.5 16724.4 17071.5 15196.4 13016.3 True False 23625.07357700972 24907.336498494664 16813.46037640256 14660.376435560345 26677.813127444384 17987.97184145818 15140.14375782953 16623.3912137494 15418.61860123571 15376.052153025897 1.536485005506467 1.6198785130676783 1.0934835684134818 0.9534551710450129 1.7350235848539561 1.1698693307253303 0.984657414474889 1.0811221923748506 1.002768360030662 1.0 13.908397514165024 -1.5228787453735273 0.227755744738334 0.9730221390228945 4.33998229221084 0.3679805598317354 0.22275359255501698 59.65617774129331 0.7769300805189852 0.3501043221496623 74.64139348211255 0.02999999999356268 1.5228787453735273 3.366960153187946 LSVPYVPQVTDEDRLS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 LSVPYVPQVTDEDRLSR 17 1 A0A1B0GUZ7;Q14156-3;Q14156-2;Q14156 A0A1B0GUZ7 EFR3A Protein EFR3 homolog A 1 LSVPYVPQVTDEDRLS(1)R 103.92 0.00038814 3406200.0 26011.0 25942.0 10618.0 9677.6 12832.0 9044.9 7037.6 8173.1 17970.0 6015.9 True False 25640.078370166804 25881.932892871726 9745.029026665288 10389.322987527223 12077.246988682658 8658.070711691716 7401.972492758734 8552.852063368471 15946.029367510942 7055.740299317122 3.6339317041825274 3.668209400419211 1.3811490521566454 1.4724639154494867 1.7116909744894573 1.2270960018936174 1.0490709945028904 1.2121835130746301 2.2600079780507585 1.0 12.784581745248218 -5.261183291499026 24.995692161397535 1.4147675518841227 3.6510707708852106 0.8706228676694403 0.34491571646071373 6.740420380672216 657819.367335783 0.0889171350130319 0.20734445982840935 5.480456165906635e-06 5.261183291499026 2.236303219001088 LSVQSNPS(ph)PQLR ddPTM_PC-9_AZD4547_30min_R2 2 LSVQSNPSPQLR 12 0 O75152;E9PBY7;E9PQ61;A0A1W2PPR9 O75152 ZC3H11A Zinc finger CCCH domain-containing protein 11A 1 LSVQSNPS(1)PQLR;LSVQSNPS(1)PQLR 139.74 5.5997e-05 34825000.0 50078.0 46127.0 56233.0 77995.0 66258.0 56976.0 45997.0 64106.0 47657.0 47066.0 True False 66001.76231289179 61036.65068735166 55487.31367801053 60014.457760737794 57059.22039633115 53413.28171306424 50090.64389200392 54199.89070933062 50176.05172630621 45418.233665775464 1.4531996730341117 1.3438798861380057 1.2216968648832007 1.3213736624452042 1.2563064608857224 1.1760316815956096 1.1028752077989619 1.1933509151451767 1.1047556823883258 1.0 15.47098397966784 -1.5228787452803378 0.14069395900569828 0.9527546075930028 2.6051057831859628 0.867815408244083 0.04588768867079481 26.84340321860059 0.25223092487895366 0.20437516870746367 8.924989856645954 0.02999999999999998 1.5228787452803378 1.65235117559296 LSVQSNPS(ph)PQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LSVQSNPSPQLR 12 0 O75152;E9PBY7;E9PQ61;A0A1W2PPR9 O75152 ZC3H11A Zinc finger CCCH domain-containing protein 11A 1 LSVQS(0.004)NPS(0.996)PQLR;LSVQSNPS(1)PQLR;LSVQS(0.003)NPS(0.997)PQLR 118.76 0.00056982 26596100.0 59367.0 68441.0 75845.0 73151.0 73999.0 66124.0 66132.0 64935.0 54014.0 53051.0 True False 69416.6605483021 75235.3701691887 77653.43244376441 69052.586628742 59499.42715626623 62656.34103535075 59867.498205782154 63230.52505431966 54803.85256555138 62668.72634851509 1.1076762620363498 1.200524959623204 1.2391097915715719 1.101866762772947 0.9494277388912667 0.9998023685195793 0.9553010200469901 1.0089645783238081 0.8745008197673374 1.0 15.93545805227746 -6.090951348430369 3.4991019160737302 0.9666151780525388 1.1837514506290514 0.8119209461213951 0.04763162639490592 0.09732841037837346 2.241267398852702 0.014139511940597881 0.019308458519602133 8.110519103514795e-07 6.090951348430369 0.21713627257651258 LSVQSNPS(ph)PQLR ddPTM_PC-9_Lapatinib_30min_R1 4 LSVQSNPSPQLR 12 0 O75152;E9PBY7;E9PQ61;A0A1W2PPR9 O75152 ZC3H11A Zinc finger CCCH domain-containing protein 11A 1 LSVQS(0.002)NPS(0.998)PQLR;LSVQS(0.003)NPS(0.997)PQLR;LSVQSNPS(1)PQLR;LSVQSNPS(1)PQLR 155.14 0.00016677 41409800.0 137228.0 127070.0 140439.0 116765.0 121626.0 123606.0 101696.0 116479.0 120787.0 100915.0 True False 135271.103555467 126775.77722215756 128892.64753021728 125352.28761662162 114472.19780591628 118319.65951965924 106961.32127765044 121891.03956749536 107182.6961165023 118358.023289215 1.1428976236357369 1.0711211094863697 1.089006422617082 1.0590941292616531 0.967168888299161 0.9996758667601097 0.9037099328389759 1.0298502474111724 0.9055803158742766 1.0 16.852797981668807 -6.094224782361391 1.5165379686809457 0.9633951476236038 1.1054291986199576 0.6905750536597837 0.0409605798624724 0.21603804912020932 0.9973585914923613 0.013539259861126285 0.021498859165956865 8.049617008687381e-07 6.094224782361391 0.1420340509963538 LSYLSAPGS(ph)EYSMYSTDSR ddPTM_PC-9_AZD4547_30min_R2 2 LSYLSAPGSEYSMYSTDSR 19 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 LSYLSAPGS(0.332)EY(0.218)S(0.1)MY(0.332)S(0.009)T(0.009)DSR;LSYLSAPGS(0.476)EY(0.343)S(0.036)MY(0.099)S(0.028)T(0.006)DS(0.011)R 101.56 0.00034222 10886200.0 58257.0 62033.0 79242.0 67122.0 73876.0 88301.0 74029.0 102001.0 87793.0 71938.0 True False 76781.5141791234 82083.95412856866 78191.19930419693 51648.05992456242 63619.59259258296 82779.52451111516 80617.43758682415 86239.08919980073 92433.55874703813 69419.4725162232 1.1060515356289937 1.1824341377613576 1.1263583036578646 0.7439996020207782 0.9164516854793902 1.1924539543536539 1.1613087029433131 1.2422896065602747 1.3315220556514107 1.0 16.083052782441158 -6.789646836745017 20.19779615252911 1.1991465004402504 1.0154824819610784 0.2715104462912582 0.13870816582994527 36.82580269986503 26367.2760476561 0.05317133192774742 0.046924110830911726 1.6231294709692063e-07 6.789646836745017 -0.18366401847917202 LSYLSAPGSEYS(ph)MYSTDSR ddPTM_PC-9_Lapatinib_30min_R1 1 LSYLSAPGSEYSMYSTDSR 19 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 LSYLS(0.003)APGS(0.027)EY(0.092)S(0.478)MY(0.272)S(0.127)T(0.003)DSR 158.34 1.0059e-05 5680500.0 16253.0 23473.0 22852.0 18581.0 23323.0 19281.0 20660.0 17995.0 17488.0 17713.0 True False 16021.22923956484 23418.64971067683 20973.19677127096 19947.508724398947 21951.186994782238 18456.39657620625 21729.67370984362 18831.11339397726 15518.317283195973 20774.668448911096 0.7711906102840641 1.1272694805343244 1.0095562691095687 0.9601842153800773 1.0566323620886864 0.8884087186081491 1.0459696992652887 0.9064459170689818 0.7469826688863169 1.0 14.342537832192306 -7.979910306275941 10.56295645146622 0.8579142216675913 0.9847708469517514 0.14004106292775165 0.10854988897405005 0.5573598093794696 286.5628147250825 0.05588290906793405 0.02651147172090669 1.047344831154282e-08 7.979910306275941 0.12685662528416008 LSYLSAPGSEYSMY(ph)STDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LSYLSAPGSEYSMYSTDSR 19 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 LSYLSAPGS(0.053)EY(0.024)S(0.019)MY(0.504)S(0.023)T(0.188)DS(0.188)R;LSYLSAPGS(0.039)EY(0.133)S(0.216)MY(0.431)S(0.181)T(0.001)DSR 128.36 3.6138e-05 6831100.0 32261.0 45661.0 48934.0 38259.0 41176.0 32246.0 36426.0 23050.8 26529.0 28318.0 True False 37722.150116205616 50193.922316963806 50100.77214322842 36115.47226735157 33107.8583843892 30554.962994161277 32975.46557859765 22445.740924341437 26916.936437062865 33451.82923483534 1.1276558256767417 1.5004836346795034 1.497699028400383 1.0796262295199817 0.9897174277666123 0.9134018585250522 0.985759712783012 0.6709869516183998 0.8046476695819279 1.0 15.029797482968345 -6.073564274001602 2.0844958006607213 0.8725236659922061 1.3860215174373158 0.7041780373172006 0.1378703875662676 0.17235149825067708 1.4851613983258272 0.045975012269595966 0.06836511501105091 8.44181296906141e-07 6.073564274001602 0.5134978514451097 LSYLSAPGSEYSMYST(ph)DSR ddPTM_PC-9_AZD4547_30min_R2 2 LSYLSAPGSEYSMYSTDSR 19 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 LSYLSAPGS(0.007)EY(0.031)S(0.021)MY(0.037)S(0.069)T(0.769)DS(0.068)R;LSYLSAPGSEYSMYS(0.052)T(0.914)DS(0.034)R 145.8 0.00044692 2755600.0 26042.0 31303.4 38802.0 25318.7 31228.0 39356.0 34453.0 44071.0 37902.0 30592.0 True False 34322.81429274993 41421.611878649055 38287.4601272236 19481.86488501562 26892.531234517024 36895.063098486324 37519.250255695166 37260.8396008316 39905.42234153342 29520.983391480087 1.162658229829013 1.403124392211255 1.2969574766358756 0.6599327883717515 0.9109632588417889 1.249791126847571 1.2709349738844886 1.262181517014954 1.3517646689591762 1.0 14.849453160242513 -6.890431333084176 21.042265751513234 1.2461609395037467 1.0910582725246676 0.09770742799352417 0.20876943519025806 7.972552464244846 1491.4508693164862 0.0814558683930234 0.07183739241841197 1.286970721708024e-07 6.890431333084176 -0.15510266697907915 LSYLSAPGSEYSMYST(ph)DSR ddPTM_PC-9_Lapatinib_30min_R1 1 LSYLSAPGSEYSMYSTDSR 19 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 LSYLSAPGS(0.002)EY(0.007)S(0.003)MY(0.004)S(0.223)T(0.723)DS(0.038)R 140.68 0.00068483 4771400.0 20757.0 26784.0 29733.0 30362.0 33606.0 26042.0 24315.0 27275.0 28736.0 22635.0 True False 20461.001373632393 26721.983293604044 27288.467512699088 32594.922764662853 31629.361151938094 24928.24436686703 25573.911725791277 28542.296072282857 25499.449076504978 26547.42959075835 0.7707338031986058 1.0065751639814673 1.0279137352792418 1.227799574841315 1.1914283845750873 0.9390078343232526 0.963329110201088 1.0751434889281695 0.9605242190898137 1.0 14.696284560873195 -4.72303854997592 2.6244358705635293 1.0545995111358994 0.6853947222044897 0.44972979827611126 0.09132103139359286 0.6130077737145061 4.787971984285126 0.025812289360198696 0.5374345370501821 1.8921756529756284e-05 4.72303854997592 -0.36920478893140973 LSYLSAPGSEYSMYSTDS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LSYLSAPGSEYSMYSTDSR 19 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 LSYLSAPGS(0.003)EY(0.011)S(0.016)MY(0.059)S(0.003)T(0.324)DS(0.584)R 134.08 0.00017333 3469300.0 38414.0 53914.0 52787.0 40655.0 42340.0 29538.0 40489.0 29256.0 27797.0 29540.0 True False 44916.731488916106 59266.22561478695 54045.64227581233 38377.23215528838 34043.78094023314 27988.97528132284 36653.588805024985 28488.060999294306 28203.47853824254 34895.36816148865 1.2871831952324053 1.6983980607545086 1.5487912901706642 1.099780119174739 0.97559598118253 0.8020828194674883 1.0503855020356756 0.8163851680101888 0.8082298604136396 1.0 15.090747932490949 -5.9084609106387225 2.7664378685237487 0.9040750312792535 1.5358184773467323 0.8228042108204098 0.12459137828996486 0.09999033108253096 1.5476880044287915 0.03692185944284652 0.05901781936187819 1.234636435573647e-06 5.9084609106387225 0.6317434460674788 LSYNTASNK ddPTM_PC-9_Lapatinib_30min_R1 1 LSYNTASNK 9 0 P49207 P49207 RPL34 60S ribosomal protein L34 0 89.88600000000001 0.041466 7015600.0 101550.0 131950.0 102540.0 101850.0 117780.0 118010.0 107340.0 113010.0 121710.0 103100.0 False True 100101.87837801079 131644.47788198394 94109.55701584628 109340.38876164018 110852.41196438944 112962.98739474622 112897.53998134624 118260.85716328824 108001.7381368812 120920.69762788563 0.8278308043347429 1.0886844060981111 0.7782750088446694 0.9042322026467129 0.91673645735588 0.9341906688495297 0.9336494264097831 0.9780034310355814 0.893161718841877 1.0 16.88370168188083 -6.929734475678358 1.7801865427712817 0.9500631853208386 0.9056322170198434 0.07845531503064607 0.07908397356778786 1.180814241685935 7.628576046214152 0.03455813706281863 0.02780695247182623 1.175616097944055e-07 6.929734475678358 -0.04443096830099513 LT(ph)FDSSFSPNTGKK ddPTM_PC-9_AZD4547_30min_R2 1 LTFDSSFSPNTGKK 14 1 P21796;C9JI87 P21796 VDAC1 Voltage-dependent anion-selective channel protein 1 1 LT(0.606)FDS(0.062)S(0.152)FS(0.179)PNT(0.001)GKK 131.35 5.6693e-05 19244000.0 112010.0 100290.0 150310.0 137230.0 138490.0 98437.0 150150.0 146980.0 134180.0 114270.0 True False 147626.85004726707 132706.78122215823 148316.79118919052 105593.74368236479 119263.05401140833 92281.71882878609 163513.0591209074 124267.61826439675 141272.48086610064 110269.44208108094 1.3387829598223349 1.2034773978867068 1.3450398259939815 0.9575975146833687 1.0815603285968782 0.8368748139754938 1.4828501535418717 1.1269451982265675 1.281157120231217 1.0 16.750673520433622 -5.737165587609647 24.998221534348776 1.117882675500959 1.286537828216769 0.19747926954853534 0.1711331343303141 433.5065663011692 446440.69340749877 0.0470818050037249 0.08149514466581474 1.8316159315002215e-06 5.737165587609647 0.16865515271581 LT(ph)FSTLELR ddPTM_PC-9_AZD4547_30min_R2 1 LTFSTLELR 9 0 Q3KR16-3;Q3KR16-2;Q3KR16 Q3KR16-3 PLEKHG6 Pleckstrin homology domain-containing family G member 6 1 LT(0.711)FS(0.273)T(0.015)LELR 97.59700000000001 0.011571 2800700.0 4705.1 5398.9 13954.0 18232.0 13856.0 13049.0 12519.0 15169.0 8516.0 13409.0 True False 6201.223927840324 7143.988843756217 13768.960842618364 14028.894081592045 11932.333571969637 12233.043967175221 13633.166747483465 12824.979598942935 8966.138374241431 12939.554991381952 0.47924553293915323 0.5521046781372528 1.0640984834322986 1.084186750698584 0.9221595008419418 0.9453991250334897 1.053603988434183 0.9911453374930338 0.6929247860697751 1.0 13.659500381519274 -5.2189793358486405 6.773831122544742 0.9734066820796093 0.5097620531304583 0.7453270112157862 0.10605177102544039 0.10989654588069406 13.852036321990946 0.02745337539554305 0.07277012059394349 6.039773665197764e-06 5.2189793358486405 -0.46364462894915104 LT(ph)FSTLELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTFSTLELR 9 0 Q3KR16-3;Q3KR16-2;Q3KR16 Q3KR16-3 PLEKHG6 Pleckstrin homology domain-containing family G member 6 1 LT(0.57)FS(0.366)T(0.064)LELR 85.807 0.016865 0.0 5920.6 6080.9 8736.0 6964.7 8878.4 8194.4 6570.5 6627.2 6872.7 5414.8 True False 6922.840642819717 6684.571564731939 8944.299371464494 6574.490438862059 7138.741254127678 7764.671238583245 5948.094673699445 6453.243022098818 6973.200235629007 6396.460376466783 1.0822924297771843 1.0450422845305423 1.3983201403656726 1.0278325905136951 1.1160455680131813 1.2139012487516139 0.9299040912663322 1.0088771980579985 1.0901654704661514 1.0 12.643058063215037 -7.258604296437451 24.998835071173477 1.0079764568088796 1.1471610617874637 0.2989797131417613 0.10502073727534592 339.87261564777407 2996900.699800466 0.04158743973260112 0.03074039509464788 5.513097886529303e-08 7.258604296437451 0.1391846049785841 LT(ph)GLGQSNAALR ddPTM_PC-9_AZD4547_30min_R2 2 LTGLGQSNAALR 12 0 Q08378-2;Q08378 Q08378-2 GOLGA3 Golgin subfamily A member 3 1 LT(1)GLGQSNAALR;LT(1)GLGQSNAALR 104.17 0.0040725 19899100.0 71286.0 65796.0 67543.0 89387.0 77216.0 77131.0 61345.0 77819.0 59805.0 68831.0 True False 93953.46515908813 87063.27028909288 66647.33568818776 68780.20816538327 66495.89124517968 72307.9863769018 66804.5861589882 65793.86165272188 62966.17020567269 66421.24764052597 1.4145091894022745 1.3107743889467756 1.0034038512628578 1.0355151492730772 1.0011237910654387 1.0886273435909404 1.0057713236664398 0.9905544383749081 0.947982346649791 1.0 16.019357201876588 -5.172155121711818 3.257290828824694 1.0106526929402344 1.3987272615972415 0.9413758720660717 0.03563700878626339 0.05521579802477704 1.1021885344089173 0.009921851472748119 0.03270312655198815 6.727363247722726e-06 5.172155121711818 0.38807456865700707 LT(ph)GLGQSNAALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LTGLGQSNAALR 12 0 Q08378-2;Q08378 Q08378-2 GOLGA3 Golgin subfamily A member 3 1 LT(1)GLGQSNAALR;LT(1)GLGQSNAALR 113.24 0.0017984000000000001 20782600.0 65790.0 69444.0 76981.0 87682.0 88621.0 67900.0 68319.0 90694.0 75502.0 61798.0 True False 76926.94758826956 76337.94138059237 78816.51899206826 82769.46180887948 71256.35122117137 64339.20446888143 61847.3297332733 88313.37859823595 76606.07391424949 73001.48820730117 1.0537723199535511 1.0457039062521127 1.0796563320497554 1.1338051297507847 0.976094501235726 0.8813409979558007 0.8472064234861407 1.2097476471637654 1.0493768797796619 1.0 16.155638254602493 -6.281104922984863 24.359794408466932 0.9914797146083454 1.076012383230175 0.1602617308701203 0.09434728425038763 1245.3140289205298 1542572.1972081733 0.032271801134094176 0.03665101035531347 5.234739530885134e-07 6.281104922984863 0.08453266862182951 LT(ph)GLGQSNAALR ddPTM_PC-9_Lapatinib_30min_R1 1 LTGLGQSNAALR 12 0 Q08378-2;Q08378 Q08378-2 GOLGA3 Golgin subfamily A member 3 1 LT(1)GLGQSNAALR 79.639 0.031802 7218200.0 26099.0 24635.0 32450.0 23774.0 32830.0 21011.0 26570.0 27827.0 25301.0 24669.0 True False 25726.823474029585 24577.9591710699 29782.086260622367 25522.419267739122 30899.003946263394 20112.408509033212 27945.66459199152 29119.944007457947 22451.33494865857 28933.003780623687 0.8891860544137049 0.849478310562751 1.0293465029222892 0.8821213124380601 1.0679500884369404 0.695137244011367 0.9658749849784563 1.006461141340584 0.775976636193375 1.0 14.82042848900608 LT(ph)GSADRY(ph)DQRHAGNK ddPTM_PC-9_Lapatinib_30min_R1 1 LTGSADRYDQRHAGNK 16 2 C9JZ01;Q6ZN06 C9JZ01 ZNF813 Zinc finger protein 813 2 LT(0.774)GS(0.28)ADRY(0.946)DQRHAGNK 65.219 0.045695 0.0 6363.0 7655.7 6709.8 6534.0 6044.3 7042.2 5693.4 4516.4 6107.7 6341.7 True False 6272.2624531687115 7637.973697014802 6158.146144577016 7014.5321567850315 5688.786157551019 6741.021522169995 5988.176393979847 4726.248431928811 5419.7865090677005 7437.854395215914 0.8432892229247025 1.0269055148387425 0.8279465847755749 0.9430854362108558 0.7648423665311451 0.9063126493180442 0.8050945979571055 0.6354316958622868 0.7286760698829691 1.0 12.860670790429138 -6.551897497635889 0.9860901533295945 0.771977516344603 0.9199836697523243 0.1341635314320878 0.10857678954148837 0.824866645116192 1.7345728129199958 0.0558214043902337 0.06347456209393393 2.8060958557102567e-07 6.551897497635889 0.14800615340772127 LT(ph)PEEEEILNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTPEEEEILNK 11 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 1 LT(1)PEEEEILNK 199.82 0.00014509 3955100.0 12616.0 12971.0 13122.0 10225.0 12917.0 9748.3 12858.0 10399.0 12010.0 10730.0 True False 14751.639622641887 14258.675157647383 13434.878245462114 9652.126399897266 10386.006575460358 9237.081987098627 11639.997156141459 10126.037268651267 12185.62352931226 12675.26406136673 1.1638131995690564 1.1249213498523296 1.0599288646309653 0.7614931218132359 0.8193917322098354 0.7287486826607874 0.9183238392341909 0.798881760539781 0.9613703880499928 1.0 13.629728182482681 -5.622925357401905 4.731952461145991 0.8435596800732692 1.133244997729356 0.6808008747187401 0.08260107618186097 0.10892514356562978 4.0996237155671675 0.022099928348801638 0.03945678216363063 2.382728956018623e-06 5.622925357401905 0.28968531765608674 LT(ph)PEEEEILNK ddPTM_PC-9_Lapatinib_30min_R1 2 LTPEEEEILNK 11 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 1 LT(1)PEEEEILNK;LT(1)PEEEEILNK 145.09 0.00028906 3988700.0 15461.900000000001 20608.4 14922.3 17563.8 19608.800000000003 14645.5 18195.9 16863.9 16666.8 12939.599999999999 True False 15241.410470634815 20560.682515976336 13695.446095743773 18855.500443119217 18455.448936384084 14019.14610532797 19137.99466877752 17647.45835869372 14789.60947481533 15176.192619066787 1.0042973790070435 1.354798468368455 0.9024296435548228 1.2424394521343838 1.2160789863194912 0.9237591046198802 1.2610537536755613 1.1628383219465814 0.974527000680937 1.0 13.889522274482173 -8.264551642023257 24.91583514123517 0.9872634767852239 1.1367881594084346 0.1461484775024564 0.14116721072969016 489.77951331320367 3920921.8605805216 0.11103237958519555 0.03335114597257253 5.438114631713636e-09 8.264551642023257 0.14952468262321073 LT(ph)PVRPAAASPIVSGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTPVRPAAASPIVSGAR 17 1 I3VM54;Q9Y2K7;Q9Y2K7-3;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 1 LT(0.523)PVRPAAAS(0.476)PIVSGAR 97.214 0.032444 0.0 6514.6 6271.3 4820.4 6052.4 8732.3 7819.5 8110.9 5098.9 6550.3 7048.6 True False 7617.393110784944 6893.873218422173 4935.336617468799 5713.303650145551 7021.268500340049 7409.431654556973 7342.576834169215 4965.059277731123 6646.085745549885 8326.455383313098 0.9148422420002186 0.8279481365189396 0.592729605848801 0.6861627652020429 0.8432481983163267 0.8898662532205581 0.8818370478372277 0.5962992713179621 0.7981890780162215 1.0 13.023486747930239 -6.283833375399994 24.31284370071042 0.819816105997007 0.7489804113500083 0.08116875701115922 0.12421869758439728 1808.0144098974397 1962929.1954635952 0.04089627855651642 0.046411025588549266 5.20195540280728e-07 6.283833375399994 -0.07083569464699879 LT(ph)PVS(ph)PESSSTEEK ddPTM_PC-9_Lapatinib_30min_R1 1 LTPVSPESSSTEEK 14 0 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 2 LT(1)PVS(1)PESSSTEEK 200.97 1.1029e-46 0.0 8766.6 18225.0 15918.0 16834.0 20380.0 16649.0 18140.0 20306.0 17478.0 15549.0 True False 8641.586676402458 18182.80113224066 14609.283485256923 18072.028516577775 19181.28846862162 15936.961080714587 19079.200440298315 21249.49089069756 15509.443588500642 18236.623932259834 0.47385890658828844 0.9970486423244181 0.8010958354749919 0.990974457975695 1.0518004066909947 0.8738986525089637 1.0462024391777909 1.165209688461475 0.8504558544449161 1.0 14.154551053843848 -4.537097510083913 2.3965772542369694 0.9813268041149777 1.3158552251633406e-09 0.6656421660428751 0.10515112071360415 1.0818691205918896 3.6536034518536176 0.027357774195140017 2.912869902863742 2.9033707011992765e-05 4.537097510083913 -0.9813268027991225 LT(ph)PVSPESSSTEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LTPVSPESSSTEEK 14 0 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 LT(0.939)PVS(0.06)PES(0.001)S(0.001)STEEK;LT(0.627)PVS(0.263)PES(0.082)S(0.025)S(0.002)T(0.001)EEK 201.3 7.1093e-08 1257724000.0 616380.0 778320.0 758400.0 785480.0 748820.0 715580.0 787720.0 809910.0 688740.0 539480.0 True False 720720.9599400774 855586.4658623183 776483.1322480184 741472.1021605186 602094.096449346 678053.7250934044 713101.4590010699 788650.7206705771 698811.5195319327 637283.4534786693 1.1309268364115794 1.3425524563552094 1.2184266326224462 1.1634887083810606 0.9447822521717159 1.0639750983525258 1.1189706167774185 1.2375195313257483 1.0965474087196316 1.0 19.281575677326884 -5.911767346259213 3.797361050491416 1.087837806831876 1.2413939694341154 0.38006605897435686 0.08712924973861773 0.2517383525972675 7.020340766399134 0.02648368465131007 0.040665722668735554 1.2252724080808764e-06 5.911767346259213 0.15355616260223948 LT(ph)PVSPESSSTEEK ddPTM_PC-9_Lapatinib_30min_R1 2 LTPVSPESSSTEEK 14 0 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 LT(1)PVSPESSSTEEK;LT(0.994)PVS(0.005)PESSSTEEK 258.09 1.525e-44 2515245100.0 93714.0 135894.0 125899.0 128812.0 133759.0 126285.0 124791.0 124182.0 123913.0 118543.0 True False 92377.6211749573 135579.34579230237 115548.07020419382 138285.2641842353 125891.55860031208 120884.08493471319 131252.06737294735 129951.94906867958 109956.61307826292 139032.9996013816 0.6644294623564989 0.9751594670403348 0.831083775330167 0.9946218853129105 0.9054796987855613 0.8694632589478558 0.9440353567085312 0.9346842076432351 0.79086701282082 1.0 17.085067822931457 -4.752560096941829 24.999708020441354 0.9129860061498525 0.6644289877632481 0.5691221149536844 0.06565659411855526 242.36459623283375 682329.7638004645 0.015194853946263472 0.17872739716280597 1.767827571794204e-05 4.752560096941829 -0.24855701838660438 LT(ph)PVSPVQHQGATVNNTNK ddPTM_PC-9_AZD4547_30min_R2 1 LTPVSPVQHQGATVNNTNK 19 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 LT(0.5)PVS(0.5)PVQHQGATVNNTNK 79.935 0.0055215 3349500.0 8521.7 8341.6 12046.0 14068.0 15600.0 13556.0 13712.0 13758.0 12760.0 16658.0 True False 11231.423337628717 11037.859071121307 11886.262169283422 10824.839948433351 13434.209275600915 12708.341177027156 14932.341436336235 11632.017227388547 13434.467549943698 16074.808490300595 0.698697178532837 0.6866557121213269 0.7394341386060986 0.6734039758523387 0.835730595714842 0.7905749660840602 0.9289281079364825 0.7236177796088339 0.8357466627394002 1.0 13.972513929436145 -6.270095811452055 23.47846447736759 0.8393457775296977 0.7014759189169704 0.5138424843670257 0.0721724189443981 240.40735602378595 652045.0141301922 0.02116247711223157 0.024405412984220026 5.369133326939759e-07 6.270095811452055 -0.13786985861272738 LT(ph)RTSGETTQTHTEPTGDSK ddPTM_PC-9_Lapatinib_30min_R1 1 LTRTSGETTQTHTEPTGDSK 20 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 LT(0.215)RT(0.172)S(0.172)GET(0.215)T(0.215)QT(0.007)HT(0.003)EPTGDSK 71.05199999999999 0.026255 0.0 17464.0 14043.0 16419.0 7036.3 12232.0 11688.0 11900.0 9856.4 11392.0 6591.6 True False 17214.960157494643 14010.48429629934 15069.093199172843 7553.7729744087155 11512.53780903728 11188.13148605874 12516.123772852812 10314.36432655724 10108.912996921805 7730.949277245095 2.2267589063304722 1.8122592444807688 1.9491905403553078 0.9770822060160359 1.4891493135160945 1.4471872838422766 1.6189633800459886 1.3341653083814744 1.3075901334233164 1.0 12.91642985709028 -5.688512779082305 9.489802163840496 1.3508409118403382 1.9811876463687135 0.6818956890415865 0.2132698071626188 0.20738809925835838 25.128296880898287 0.05697023224133925 0.09871449351178063 2.0487417649989846e-06 5.688512779082305 0.6303467345283753 LT(ph)S(ph)GS(ph)LS(ph)TS(ph)ERRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTSGSLSTSERRK 13 2 H0YCW5 H0YCW5 DENND5A 5 LT(1)S(1)GS(1)LS(0.564)T(0.564)S(0.872)ERRK 53.255 0.027288 2350300.0 21836.0 23645.0 24969.0 20277.0 31958.0 29382.0 26191.0 23822.0 22523.0 18542.0 True False 25532.403519341162 25992.319335638906 25564.35565545982 19140.945428920975 25696.059312422527 27841.156195945136 23709.998873580702 23196.697741495384 22852.35626567029 21903.517821608762 1.1656759305645574 1.186673279942109 1.1671346978903765 0.8738754014223966 1.1731475976462675 1.2710814957987542 1.0824744713011245 1.0590398277764699 1.0433189979705204 1.0 14.41887497249098 -8.883601942400386 0.01738199220938274 9.834217266884565e-07 2.1266373932624987 0.15712259324222422 0.09940423419859028 1482.1175022760056 12.165488157305058 770.873649789866 714.9590591867044 1.307368622888755e-09 8.883601942400386 2.126636409840772 LT(ph)S(ph)T(ph)VMLWLQT(ph)NK ddPTM_PC-9_AZD4547_30min_R2 1 LTSTVMLWLQTNK 13 0 B1AK87;B1AK85;B1AK88;P47756-2;P47756 B1AK87 CAPZB F-actin-capping protein subunit beta 4 LT(1)S(1)T(1)VMLWLQT(1)NK 50.353 0.041152 0.0 0.0 0.0 936.99 2558.9 894.93 489.35 1229.4 816.98 670.49 842.34 True False 0.0 0.0 924.5649003816098 1968.9851396108986 770.6844171162523 458.7508671420948 1338.8142183366222 690.7345133327441 705.9307325675355 812.8499329883414 0.0 0.0 1.137436152553476 2.4223230632155808 0.9481263217712613 0.5643733837260151 1.647061977866737 0.8497688014727944 0.8684637888475543 1.0 9.666845218683498 -5.269678574229478 6.693700961917073 1.2070435513165887 1.315959743574991e-10 0.47692322558272837 0.49378200461227084 0.114352446623853 30.13455046465878 0.13441928958053298 0.30979809546777354 5.374294061932602e-06 5.269678574229478 -1.2070435511849926 LT(ph)SDEEGEPSGK ddPTM_PC-9_AZD4547_30min_R2 1 LTSDEEGEPSGK 12 0 Q8WVC0-2;Q8WVC0 Q8WVC0-2 LEO1 RNA polymerase-associated protein LEO1 1 LT(0.754)S(0.246)DEEGEPSGK 179.59 0.0019105999999999997 21939000.0 49278.0 60022.0 59925.0 58436.0 59918.0 60517.0 65076.0 64552.0 57266.0 62953.0 True False 64947.378953925654 79422.93770581714 59130.355345700584 44964.483027200156 51599.419959965104 56732.86242329246 70867.63793108345 54576.97165739105 60292.96384914388 60749.03463140188 1.069109646729326 1.3073942357721433 0.973354650069376 0.7401678611030552 0.8493866655338217 0.9338891188563281 1.166564018030521 0.8984006410725673 0.9924925427206336 1.0 15.890573862448031 -5.381194264471553 6.433745289235875 0.9353945230540073 1.1860410290907393 0.4121516136838883 0.11682951804573445 0.21940370286693747 10.577316895767982 0.03224314598955589 0.06794275932492529 4.157246109236249e-06 5.381194264471553 0.250646506036732 LT(ph)SDEEGEPSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LTSDEEGEPSGK 12 0 Q8WVC0-2;Q8WVC0 Q8WVC0-2 LEO1 RNA polymerase-associated protein LEO1 1 LT(0.594)S(0.406)DEEGEPSGK;LT(0.871)S(0.129)DEEGEPSGK 143.31 0.00020553 9329500.0 50495.0 65551.0 60165.0 62377.0 58999.0 47240.0 61961.0 45768.0 46589.0 39918.0 True False 59042.80617828962 72058.47006853316 61599.56177703311 58882.218918962564 47438.56947786526 44762.65123873281 56091.60552120711 44566.63849520447 47270.27598727135 47154.81740928584 1.2521054989105476 1.5281253120565204 1.3063259527096118 1.2486999664930807 1.0060174566283773 0.9492699515769526 1.1895201509180569 0.9451131600910048 1.0024485001602992 1.0 15.52511754594209 -6.036660143398707 2.1891038995515695 1.0164234305669413 1.384509533469517 0.7489517880729446 0.09182915642417737 0.1474509903318528 1.4085332520880651 0.028687982700782128 0.043454468562646086 9.190515177622198e-07 6.036660143398707 0.3680861029025757 LT(ph)SDEEGEPSGK ddPTM_PC-9_Lapatinib_30min_R1 1 LTSDEEGEPSGK 12 0 Q8WVC0-2;Q8WVC0 Q8WVC0-2 LEO1 RNA polymerase-associated protein LEO1 1 LT(0.655)S(0.345)DEEGEPSGK 202.18 4.0096e-06 8728100.0 56200.0 71193.0 63261.0 62966.0 73686.0 72506.0 85187.0 80231.0 82706.0 65025.0 True False 55398.577694182204 71028.15698258477 58059.924774521794 67596.72968841848 69351.93435224994 69405.08739974123 89597.56603680771 83958.82515766568 73390.77934720987 76264.4846096338 0.7264007352536964 0.9313398936103533 0.7612970188116581 0.8863461155532361 0.9093608211900162 0.9100577779420791 1.174826873811846 1.1008902189192782 0.962319220051991 1.0 16.21872374845571 -7.056342230216981 4.092822417822762 1.0677952724020952 0.8492827260450424 0.6196654282535052 0.07977741137655953 0.14911518086224593 5.067736693860786 0.030857739411230066 0.024283616270995567 8.783301074590612e-08 7.056342230216981 -0.21851254635705275 LT(ph)VENSPK ddPTM_PC-9_AZD4547_30min_R2 1 LTVENSPK 8 0 F8VVL1;O43583 F8VVL1 DENR Density-regulated protein 1 LT(0.531)VENS(0.469)PK 92.23899999999999 0.019864 110980000.0 423120.0 556300.0 323390.0 250840.0 278660.0 420410.0 457250.0 393490.0 396220.0 324540.0 True False 557663.3585572683 736113.0959605811 319101.63730072795 193012.7134393677 239972.86902172788 394121.696240336 497944.364189377 332685.16200066276 417163.380300838 313177.9533822883 1.780659693744607 2.3504626938475033 1.0189147539105627 0.6163036425612056 0.766250837359548 1.2584592624859572 1.5899725980441193 1.0622879369626717 1.3320330367943154 1.0 18.256623130023783 -5.269500103989369 24.949656554601454 1.0794978438887524 2.065561206064858 0.6484404466170828 0.29011765445502374 336.85994987046934 1042655.4771446369 0.08286875812300509 0.17748924340987893 5.376503043849e-06 5.269500103989369 0.9860633621761055 LTAGVPDT(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 4 LTAGVPDTPTR 11 0 P16144-4;P16144-2;P16144-3;P16144 P16144-4 ITGB4 Integrin beta-4 1 LTAGVPDT(0.966)PT(0.034)R;LTAGVPDT(0.977)PT(0.023)R;LTAGVPDT(0.998)PT(0.002)R;LT(0.002)AGVPDT(0.888)PT(0.109)R 155.88 0.00019076 247317000.0 516049.0 958448.0 876410.0 756910.0 690323.0 569266.0 696320.0 894118.0 605069.0 536516.0 True False 680141.8475139895 1268247.5725278216 864788.2307638794 582416.0936429272 594483.5672923496 533669.7070287361 758291.1310494185 755952.6078876427 637051.7120671537 517732.7381427615 1.3136929489022282 2.4496182665159383 1.670337158639212 1.1249358032335395 1.1482441103201486 1.0307822312785253 1.464638171751705 1.4601213178046963 1.2304644175147577 1.0 18.981848022426803 -5.603592845926119 4.80794692653323 1.2313861264824324 1.9221839486586714 0.4720949973868832 0.29540074524921583 0.15833661398401372 6.55001855600174 0.07816326181248708 0.14016119547113437 2.491191733288167e-06 5.603592845926119 0.690797822176239 LTAGVPDT(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LTAGVPDTPTR 11 0 P16144-4;P16144-2;P16144-3;P16144 P16144-4 ITGB4 Integrin beta-4 1 LTAGVPDT(0.984)PT(0.016)R;LTAGVPDT(0.993)PT(0.007)R;LTAGVPDT(0.986)PT(0.014)R;LTAGVPDT(0.985)PT(0.015)R;LTAGVPDT(0.97)PT(0.03)R;LTAGVPDT(0.685)PT(0.315)R 124.47 0.0012468 174653500.0 446482.0 489917.0 414583.0 303831.0 602696.0 301775.0 316105.0 251647.0 272576.0 267461.0 True False 522062.5841785335 538552.7220113426 424468.2310347828 286808.334103392 484602.04528943734 285949.38775547413 286161.24599798495 245041.53289203608 276561.9083368704 315949.56207988865 1.6523605247046638 1.7045528357946202 1.3434683315922904 0.9077662023499553 1.533795590977602 0.9050475837759544 0.9057181282803245 0.7755716807421201 0.8753356279916001 1.0 18.269334740607853 -5.24058970532187 0.49689542189933944 0.8524285719491411 2.108081948939067 0.6789546859494033 0.1929832628195271 1.7397011481474025 0.4594952726972895 0.13509831065078462 1.212303162511651 5.74659108369732e-06 5.24058970532187 1.255653376989926 LTAGVPDT(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 4 LTAGVPDTPTR 11 0 P16144-4;P16144-2;P16144-3;P16144 P16144-4 ITGB4 Integrin beta-4 1 LTAGVPDT(0.977)PT(0.023)R;LTAGVPDT(0.996)PT(0.004)R;LTAGVPDT(0.988)PT(0.012)R;LT(0.029)AGVPDT(0.923)PT(0.049)R 148.89 0.00072134 238021000.0 813578.0 1359670.0 587333.0 375984.0 595229.0 423610.0 364986.0 361825.0 682485.0 239650.0 True False 801976.2285280665 1356521.7676528739 539044.7479109442 403635.1176058557 560218.8004852401 405493.18778314034 383883.18918978673 378636.7104071032 605616.3524143419 281073.183186448 2.853264831017625 4.8262226665467205 1.917809240283775 1.4360499035516563 1.9931421209743183 1.4426605312757965 1.3657766452061006 1.3471107635193253 2.1546571805557497 1.0 18.100586289131684 -5.384939987512916 5.783190550878192 1.5670770209532303 3.8209367595581467 0.7368121605764422 0.5427373241911188 0.09656398932006599 4.1101431606756185 0.1317488237020739 0.279522165156435 4.121544682570911e-06 5.384939987512916 2.253859738604916 LTANETQS(ph)ASSTLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LTANETQSASSTLQK 15 0 O95819-6;E7EN19 O95819-6;E7EN19 MAP4K4 1 LTANET(0.129)QS(0.864)AS(0.006)S(0.001)TLQK;LTANET(0.045)QS(0.954)AS(0.001)STLQK 143.28 8.5906e-05 6595200.0 28109.0 29380.0 26484.0 25999.0 30073.0 22160.9 18923.5 17474.7 19724.4 14444.5 True False 32867.29852194364 32296.65223434432 27115.47900112931 24542.360319895262 24180.411530836835 20998.743391965167 17130.929085724278 17016.00764097511 20012.83203510132 17063.17350740091 1.9262125247503294 1.892769373782439 1.5891228550989274 1.438323317127987 1.4171110385971828 1.2306470061303227 1.003970866163553 0.9972358092470113 1.172866936295352 1.0 14.058598371903436 -5.69183800064071 0.5310863325907006 1.001885531318253 2.179319486435201 0.9476191883284459 0.07609915198827504 0.38720977127497114 0.16188175291632956 0.056334584106578905 0.25545278573199476 2.0331152566915473e-06 5.69183800064071 1.177433955116948 LTANETQS(ph)ASSTLQK ddPTM_PC-9_Lapatinib_30min_R1 2 LTANETQSASSTLQK 15 0 O95819-6;E7EN19 O95819-6;E7EN19 MAP4K4 1 LTANETQS(0.987)AS(0.011)S(0.002)TLQK;LTANET(0.001)QS(0.992)AS(0.006)S(0.002)TLQK 203.06 3.1095999999999997e-50 0.0 27538.0 32259.0 31279.0 31579.0 30623.0 24414.0 19041.4 22531.3 26925.0 18461.5 True False 27145.303070149286 32184.30626748705 28707.36136043167 33901.425004455865 28821.815347134434 23369.870131813677 20027.27052171425 23578.18645255459 23892.422967180435 21652.545676597547 1.2536772107811973 1.486398262273263 1.325819226487493 1.5657015812739803 1.3311051632273225 1.0793128198811397 0.9249383800335347 1.0889336895863617 1.1034463718048537 1.0 14.402249031249708 -6.73213058842317 3.6588353732545276 1.032720472508773 1.4113541084373635 0.7916269090203556 0.09141051515862894 0.09686879555515011 2.7351389755124744 0.03133655611036295 0.02981181819292282 1.8529743670032262e-07 6.73213058842317 0.37863363592859045 LTATEGPGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 LTATEGPGSPR 11 0 Q8NC74 Q8NC74 RBBP8NL RBBP8 N-terminal-like protein 1 LTATEGPGS(1)PR;LTATEGPGS(1)PR 110.93 0.001875 8730800.0 37458.0 33397.0 51542.0 55292.0 54015.0 47568.0 34583.0 53395.0 37405.0 42818.0 True False 49368.86482519879 44191.92713606963 50858.51940305547 42545.283652884355 46515.9496167682 44593.565440308914 37660.820003851804 45144.02964503643 39382.15193617901 41318.95485278489 1.1948236590469166 1.0695315816559456 1.2308762306369814 1.0296795696906842 1.1257774980635318 1.0792520188177828 0.911465939495163 1.092574335577458 0.953125558874698 1.0 15.33451614179274 -6.697164476035878 0.9906255704273882 0.9936013355185518 1.146934701575249 0.46284061789382336 0.06971158608173772 0.49155606068994256 1.041161777229997 0.03721168128655049 0.03626777841508306 2.0083320729041688e-07 6.697164476035878 0.15333336605669712 LTATEGPGS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTATEGPGSPR 11 0 Q8NC74 Q8NC74 RBBP8NL RBBP8 N-terminal-like protein 1 LTATEGPGS(1)PR 101.56 0.0036849000000000005 4798100.0 29897.0 26841.0 22148.0 30235.0 30332.0 22205.0 28294.0 22503.0 23599.0 24518.0 True False 34957.97160733389 29505.59709401075 22676.09231675773 28541.03097319257 24388.662340083873 21040.53071033155 25613.78748917921 21912.320093899354 23944.090730078267 28962.919315618787 1.2069906084530009 1.0187369847796839 0.7829353135866118 0.9854335007521599 0.8420650582322977 0.7264644313318601 0.8843648394023079 0.7565646216499569 0.8267153759312507 1.0 14.821919405654986 -4.937676393862775 2.4816949384314517 0.8426955799365511 1.2332635067027267 0.6309729312399551 0.08567628786319238 0.22861107964218158 2.2839927233144994 0.022091279396835146 0.16632454788459258 1.15431305150665e-05 4.937676393862775 0.3905679267661756 LTATEGPGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 LTATEGPGSPR 11 0 Q8NC74 Q8NC74 RBBP8NL RBBP8 N-terminal-like protein 1 LTATEGPGS(1)PR;LTATEGPGS(1)PR 105.36 0.0025681999999999996 7685900.0 30641.0 34221.0 48493.0 37855.0 36455.0 46110.0 35285.0 35742.0 41012.0 30003.0 True False 30204.0537211288 34141.76337703195 44506.092728393276 40638.98298057809 34310.788573287624 44137.98278765987 37111.884649169035 37402.70380258603 36392.79668449409 35188.97857351549 0.8583384612323324 0.9702402502449529 1.2647736459702241 1.1548781643569637 0.9750436063839368 1.254312701786682 1.0546451233768064 1.0629096188298195 1.0342100896297297 1.0 15.102836017299694 -5.021978011268964 8.634051200549475 1.1047324991244258 0.885320814887118 0.40708682612928837 0.09394401756969839 0.20060466350577155 75.73305525625017 0.023553309463721733 0.06851678760724159 9.50652924874079e-06 5.021978011268964 -0.21941168423730784 LTATPT(ph)PLGGMTGFHMQTEDR ddPTM_PC-9_AZD4547_30min_R2 1 LTATPTPLGGMTGFHMQTEDR 21 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 LT(0.044)AT(0.379)PT(0.568)PLGGMT(0.009)GFHMQTEDR 56.016999999999996 0.020181 14683000.0 29931.0 26091.0 36947.0 53354.0 44106.0 40799.0 30299.0 37820.0 31429.0 33619.0 True False 39448.43539652475 34524.40551268654 36457.05863925907 41054.059611082805 37982.64322497785 38247.8320803726 32995.55230305947 31975.78801714165 33090.27277642481 32442.00904282718 1.215967708548761 1.0641882710503643 1.1237608186081067 1.2654598411857518 1.1707857911893311 1.1789600338832613 1.0170625456488083 0.9856290951318686 1.0199822314561915 1.0 14.98557554393743 -7.287746757640688 6.025579190792799 1.00326882178799 1.1675080585085875 0.7179749673069188 0.050410271171462205 0.10905804076372547 13.85121271068232 0.022304022424994737 0.01534989224078314 5.1552916824010206e-08 7.287746757640688 0.1642392367205976 LTATPT(ph)PLGGMTGFHMQTEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTATPTPLGGMTGFHMQTEDR 21 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 LT(0.015)AT(0.145)PT(0.834)PLGGMT(0.006)GFHMQTEDR 52.666000000000004 0.035013999999999997 13854000.0 57903.0 52778.0 61681.0 57150.0 68787.0 68592.0 68412.0 52796.0 65344.0 50328.0 True False 67704.83426362026 58017.45104234934 63151.70896649515 53948.07078279991 55308.6811416111 64994.91477068506 61931.52010001168 51410.160941985996 66299.53238129728 59452.06800377118 1.1388137795194204 0.9758693514020264 1.0622289701089842 0.9074212654701576 0.9303071028261414 1.0932321944892194 1.041705060555391 0.8647329297060774 1.1151762185478855 1.0 15.859439373656546 -4.756500880238079 24.941809209838517 0.9959889588709367 1.1388140054194722 0.22618699765066796 0.07742540307609946 224.4764753089134 1133579.989875692 0.018743331743986614 0.1513225963878797 1.7518588834969507e-05 4.756500880238079 0.14282504654853545 LTATPT(ph)PLGGMTGFHMQTEDR ddPTM_PC-9_Lapatinib_30min_R1 1 LTATPTPLGGMTGFHMQTEDR 21 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 LT(0.016)AT(0.101)PT(0.654)PLGGMT(0.228)GFHMQTEDR 54.668 0.022581 8936700.0 29153.0 29888.0 40086.0 28920.0 30131.0 41719.0 24072.0 32429.0 34230.0 21470.0 True False 28737.272873994574 29818.796172313232 36790.28381643477 31046.873274291887 28358.753819825244 39934.77562173894 25318.330374799418 33935.76972788492 30374.656942120197 25181.060893023252 1.1412256614635572 1.1841755317217364 1.4610299372504996 1.2329454031420033 1.1261937668274498 1.5859052083386764 1.0054512985914028 1.3476703730654684 1.2062500889522054 1.0 14.620051445484128 -8.550860095988876 20.135660368839194 0.9999999935043792 1.2626066769932882 0.19119271508468005 0.16050904034519203 896.7049281120776 645279.4997242208 0.14703323077516045 0.037963816928317545 2.8128068045541704e-09 8.550860095988876 0.26260668348890903 LTATPTPLGGMT(ph)GFHMQTEDR ddPTM_PC-9_Lapatinib_30min_R1 1 LTATPTPLGGMTGFHMQTEDR 21 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 LT(0.002)AT(0.029)PT(0.393)PLGGMT(0.573)GFHMQT(0.004)EDR 53.327 0.029927999999999996 8109000.0 38924.0 42806.0 44691.0 36042.0 39753.0 48235.0 30407.0 37739.0 39315.0 30859.0 True False 38368.9366222126 42706.88533699279 41016.67849224884 38692.64891258743 37414.806697405074 46172.101491276815 31981.325677406327 39492.491712992945 34886.93069469634 36192.93703296718 1.0601222163115238 1.1799784388344121 1.133278530418458 1.069066289849407 1.0337598925261282 1.2757213223458455 0.8836344408378737 1.0911657066410578 0.9639154363990623 1.0 15.143420565761346 -7.274265364225542 24.999876135555436 0.9922760506159065 1.1214483344949209 0.42418701200413367 0.0800038033940541 828.8861444291188 1615623.9664674322 0.032136392785936656 0.021820483067188257 5.31783227815198e-08 7.274265364225542 0.12917228387901436 LTDEDFS(ph)PFGSGGGLFSGGK ddPTM_PC-9_AZD4547_30min_R2 1 LTDEDFSPFGSGGGLFSGGK 20 0 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 LTDEDFS(0.997)PFGS(0.003)GGGLFSGGK 178.57 1.5794e-09 41074000.0 171460.0 154270.0 233810.0 229820.0 223670.0 231860.0 199240.0 247070.0 202730.0 203470.0 True False 225980.71341044878 204134.76058572516 230709.52663125997 176838.5496836051 192617.2813252341 217361.75754688124 216971.9740209768 208891.00860378626 213445.89391850232 196346.5772314478 1.150927694268228 1.0396654908075982 1.1750117057518457 0.9006449319213383 0.9810065652337921 1.1070310499513385 1.1050458687915725 1.0638892286752288 1.0870874192367423 1.0 17.583042923196118 -1.5228789156783762 0.005589310785348513 1.968216491464173e-08 2.196828836461117 0.05137824613087982 0.0767662494033502 201402.07009135623 87.42893137874452 15815.568074655102 18656.073664024556 0.029999988229322802 1.5228789156783762 2.196828816778952 LTDEDFS(ph)PFGSGGGLFSGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LTDEDFSPFGSGGGLFSGGK 20 0 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 LTDEDFS(1)PFGSGGGLFSGGK;LTDEDFS(1)PFGSGGGLFSGGK 197.94 1.3244000000000002e-15 12038900.0 72844.0 80413.0 101830.0 97634.0 112516.0 113209.0 130073.0 110514.0 109444.0 102152.0 True False 85175.05046541894 88395.87120899711 104258.01339242561 92163.88351369876 90469.29750286431 107272.12074694541 117751.54379303043 107613.12459926186 111044.41145229393 120671.3489652128 0.7058431947253133 0.7325340436401346 0.8639831599336903 0.7637594532921631 0.7497164677337356 0.8889609809356641 0.9758036584722021 0.8917868700571552 0.9202218455708643 1.0 16.88072365166917 -6.881108339148181 4.031819381892711 0.9374714352474863 0.7671480152069718 0.7699629991371919 0.047670030140537174 0.11767021916393203 3.5047638119424107 0.018018854922445923 0.015835235104911676 1.314896776984141e-07 6.881108339148181 -0.17032342004051448 LTDEDFSPFGS(ph)GGGLFSGGK ddPTM_PC-9_AZD4547_30min_R2 1 LTDEDFSPFGSGGGLFSGGK 20 0 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 LT(0.001)DEDFS(0.347)PFGS(0.652)GGGLFSGGK 100.45 0.00031401 30869000.0 145690.0 119180.0 169510.0 230770.0 217950.0 199620.0 147050.0 199470.0 189020.0 211930.0 True False 192016.38945974762 157702.60430807504 167262.18664413347 177569.54186095847 187691.40459084781 187137.72984347562 160137.16512640347 168646.49486460202 199011.21130802186 204510.39520647164 0.9389077228367282 0.7711226813133879 0.8178664291136265 0.8682665821543499 0.917759727574515 0.9150524092163786 0.7830270190653663 0.8246353183873035 0.9731104920466372 1.0 17.641814651255032 -8.34152775330444 5.1096760363206295 0.9950010487705125 0.8528749406022296 0.48664465060538664 0.05433332783486329 0.19796852698874318 8.724368879694504 0.053790130938370484 0.014152538535070553 4.554830778878864e-09 8.34152775330444 -0.14212610816828297 LTEDLEYHELLDR ddPTM_PC-9_AZD4547_30min_R2 2 LTEDLEYHELLDR 13 0 P22059;H0YCV6 P22059 OSBP Oxysterol-binding protein 1 0 ; 151.66 1.621e-05 1456800.0 11116.0 10667.2 14871.5 22828.0 16874.6 15624.6 14861.0 18232.3 14250.7 14008.4 False True 14650.656772836512 14115.163791534624 14674.294193134523 17565.357289084215 14531.853066798412 14647.591292016712 16183.60021042829 15414.916971574088 15003.962908619345 13517.970179825106 1.0837911741144306 1.0441777577376816 1.0855397665424038 1.299407903362565 1.0750025982810996 1.0835644033212553 1.197191589798112 1.1403277834256567 1.1099272086730898 1.0 13.722590916424709 -5.538624006580641 24.99994904838915 1.1383576231741785 1.0642029475055135 0.10700435040984158 0.0756005907626015 413.03870151622175 655810.5017305311 0.01997825409126178 0.03461554377948191 2.8931835918984953e-06 5.538624006580641 -0.07415467566866507 LTEGCS(ph)FR ddPTM_PC-9_AZD4547_30min_R2 1 LTEGCSFR 8 0 H0YMV8;Q71UM5;C9J1C5;P42677 H0YMV8;P42677 RPS27L;RPS27 40S ribosomal protein S27;40S ribosomal protein S27-like 1 LTEGCS(1)FR 104.42 0.0038583 25252000.0 52062.0 67029.0 83390.0 120140.0 117740.0 81088.0 61905.0 69742.0 83703.0 61397.0 True False 68616.63304312833 88694.81342646375 82284.19411394194 92443.57914449686 101393.83334033648 76017.55454136762 67414.4250741244 58964.97641172637 88127.36969693871 59247.50971779239 1.1581353101584004 1.4970217963410561 1.38882114211851 1.560294763186232 1.711360255026673 1.2830506278399594 1.1378440274575699 0.9952313049542203 1.4874442844383977 1.0 15.854466895698835 -6.992339000177904 24.77266109704129 1.1626917452332266 1.469372462506245 0.39010251533372975 0.18208232923433101 170.27135588601288 550586.996969143 0.06384952431780336 0.056201931574219016 1.0177966095257501e-07 6.992339000177904 0.3066807172730184 LTEGCS(ph)FR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTEGCSFR 8 0 H0YMV8;Q71UM5;C9J1C5;P42677 H0YMV8;P42677 RPS27L;RPS27 40S ribosomal protein S27;40S ribosomal protein S27-like 1 LTEGCS(1)FR 72.243 0.033212 4271100.0 48149.0 53082.0 45615.0 46229.0 51526.0 53267.0 38059.0 53066.0 43767.0 36062.0 True False 56299.674713901695 58351.63015328335 46702.63459585083 43638.93900644019 41429.85018248591 50473.58474880569 34453.77599670147 51673.073728074625 44407.00957597085 42599.755133365084 1.3215962048994625 1.3697644498332116 1.0963122780786192 1.0243941278493687 0.9725372846107541 1.1848327435402004 0.8087787333246078 1.2129899236815826 1.0424240570620154 1.0 15.378557517303493 -5.338431748695666 3.934233027289098 1.0396329381665335 1.3480659286843961 0.5692815818234429 0.10619544683902646 0.14809727588293084 4.336523234144357 0.026974677425177465 0.06283079528236904 4.587417334319652e-06 5.338431748695666 0.30843299051786266 LTEGCS(ph)FR ddPTM_PC-9_Lapatinib_30min_R1 1 LTEGCSFR 8 0 H0YMV8;Q71UM5;C9J1C5;P42677 H0YMV8;P42677 RPS27L;RPS27 40S ribosomal protein S27;40S ribosomal protein S27-like 1 LTEGCS(1)FR 96.665 0.0060501999999999995 21755000.0 44352.0 46630.0 82197.0 55305.0 67041.0 40139.0 51039.0 60208.0 75655.0 56112.0 True False 43719.53234683934 46522.03109993868 75439.07994959547 59372.31419207163 63097.780187677294 38422.348538579055 53681.54968425505 63005.48348011025 67133.93721753145 65810.88443545974 0.6643206928743645 0.7069048151991104 1.1463009591305224 0.9021655718712857 0.9587742320885664 0.5838296942545967 0.8156940929262265 0.9573717785528209 1.0201038596186809 1.0 16.006038589990805 -7.8783987322375655 4.217430174968423 1.0036259927510547 0.8322477218190494 0.2092260347297792 0.1503239418732808 0.40157592466984454 12.550107017859402 0.09538642214431349 0.043187742817389706 1.3231261954862733e-08 7.8783987322375655 -0.1713782709320053 LTEGCSFR ddPTM_PC-9_AZD4547_30min_R2 1 LTEGCSFR 8 0 H0YMV8;Q71UM5;C9J1C5;P42677 H0YMV8;P42677 RPS27L;RPS27 40S ribosomal protein S27;40S ribosomal protein S27-like 0 98.62899999999999 0.025099 5081200.0 12798.0 12115.0 18282.0 22328.0 18196.0 17354.0 16555.0 21559.0 19359.0 16983.0 False True 16867.497785063122 16030.936828262526 18039.5687347534 17180.62456416121 15669.799485822723 16268.851636628018 18028.362928715454 18227.551926535078 20382.277217818206 16388.430339222894 1.0292320518758689 0.9781862262852123 1.1007502464454324 1.0483386272230317 0.9561501108693582 0.9927034682321781 1.1000664832169842 1.1122207282359777 1.243699170446893 1.0 14.000390061304524 -7.427977863291344 3.720878150349322 1.1302606054783728 1.0184302311268554 0.33225747354980506 0.06652599543062558 0.26372206990844976 6.698647437658167 0.030196315939254162 0.019043486455889908 3.7326918345900755e-08 7.427977863291344 -0.11183037435151744 LTEGCSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LTEGCSFR 8 0 H0YMV8;Q71UM5;C9J1C5;P42677 H0YMV8;P42677 RPS27L;RPS27 40S ribosomal protein S27;40S ribosomal protein S27-like 0 ; 110.12 0.017357 7609400.0 28984.0 30527.0 29451.0 38485.0 38612.0 33385.0 33698.0 27232.0 30187.0 26335.0 False True 33890.41873990587 33557.51881408539 30153.223533539458 36328.81022005343 31046.25577856122 31634.231829066375 30505.88148760729 26517.18885468904 30628.42776680675 31109.327032254707 1.0893973599868516 1.07869639157711 0.9692663393932005 1.167778723801613 0.9979725934402858 1.0168729074810083 0.9806024237032915 0.8523870936582956 0.9845416371447268 1.0 14.925059565880117 -6.995579056167887 1.5643780387537587 0.9398250968903247 1.066428758400208 0.40740501727072653 0.061623506081677 0.36189755888848996 1.7946513475724242 0.029606648002186882 0.022196163328369902 1.0102315877436086e-07 6.995579056167887 0.12660366150988323 LTEGCSFR ddPTM_PC-9_Lapatinib_30min_R1 2 LTEGCSFR 8 0 H0YMV8;Q71UM5;C9J1C5;P42677 H0YMV8;P42677 RPS27L;RPS27 40S ribosomal protein S27;40S ribosomal protein S27-like 0 ; 122.18 0.015388999999999998 17396800.0 68702.0 59581.0 55939.0 53313.0 56713.0 61873.0 57627.0 53625.0 58634.0 53882.0 False True 67722.29688159631 59443.04385514574 51339.911350784474 57233.815866954435 53377.252842048016 59226.8360230076 60610.64408892344 56116.61326768718 52030.021476607544 63195.43190674797 1.0716327879763248 0.9406224795308101 0.8123990896453139 0.9056638136663016 0.8446378358614941 0.9372012222402961 0.9590985022202448 0.887985279545104 0.8233193429769378 1.0 15.947532656248217 -4.820075622288435 3.6721146272367347 0.8935735511865129 1.0838049845651023 0.4638342688122362 0.05645656136302909 0.20862509742709356 4.792713306459739 0.013982770075220299 0.10108872079018882 1.5132977198733165e-05 4.820075622288435 0.1902314333785894 LTEVPVEPVLTVHPES(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 LTEVPVEPVLTVHPESK 17 0 Q9H307 Q9H307 PNN Pinin 1 LTEVPVEPVLTVHPES(1)K 149.18 3.697e-12 0.0 8509.2 7247.3 5547.7 9840.0 10504.0 9956.5 8238.8 7937.9 8437.8 8547.6 True False 11214.948597644865 9589.847996324139 5474.133873197216 7571.540026484517 9045.700912237951 9333.918481046834 8972.037239329564 6711.279949795577 8883.804881889886 8248.351125686957 1.3596594551751502 1.1626381867352253 0.6636640208186224 0.9179458913800699 1.0966677793417272 1.1316102259491854 1.0877370643677993 0.8136510979625196 1.0770400952287305 1.0 13.00989003304525 -5.006900252571255 15.082836903318762 0.97462753016688 1.310457440838317 0.43786655470332814 0.13845888347383148 1.6524149579010978 3636.057779320255 0.036676934971559626 0.11895905756670282 9.842371363793e-06 5.006900252571255 0.33582991067143697 LTEVPVEPVLTVHPES(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTEVPVEPVLTVHPESK 17 0 Q9H307 Q9H307 PNN Pinin 1 LTEVPVEPVLTVHPES(1)K 104.3 0.0022273 0.0 6673.7 5827.3 7135.4 7233.4 8766.1 5459.1 6507.7 6600.0 6142.1 5042.0 True False 7803.425598416699 6405.795832715953 7305.534997155187 6828.136048999209 7048.44563297538 5172.815185803694 5891.243544332068 6426.756993278039 6231.9165927884105 5956.07468754996 1.3101624824699185 1.0755062971433265 1.2265687353494772 1.1464154509801778 1.1834045076212383 0.8684940094214196 0.9891151225229917 1.0790255882304416 1.046312700848941 1.0 12.540146129697337 -6.729470836594186 24.933108075714273 1.0010614483318547 1.1819258566296023 0.6171631544040606 0.0754121869372362 135.35674542746122 105567.9236470872 0.02470647672442124 0.02470445604581604 1.864357367927408e-07 6.729470836594186 0.18086440829774753 LTEVPVEPVLTVHPES(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 LTEVPVEPVLTVHPESK 17 0 Q9H307 Q9H307 PNN Pinin 1 LTEVPVEPVLT(0.076)VHPES(0.924)K 74.561 0.0054036 1529700.0 14284.0 14734.0 12306.0 14217.0 11111.0 12268.0 10346.0 12853.0 12272.0 9130.9 True False 14080.307540635222 14699.88432825427 11294.248182533716 15262.565606521695 10457.472825066476 11743.326238104783 10881.665256633207 13450.197302183384 10889.798130110983 10709.163898840521 1.3147905544857421 1.3726453780248729 1.054633983494878 1.4251874143203813 0.9764975981176929 1.0965679813132965 1.0161078268501766 1.2559521386762633 1.016867258076984 1.0 13.386558227883851 -5.710297378158866 0.7782246686775212 1.073235356004006 1.3605015722248306 0.36201241499561865 0.12973079678955815 1.1306152680877941 1.1665554808976815 0.05956173981472202 0.22820382833478492 1.9485099230656003e-06 5.710297378158866 0.2872662162208246 LTFDSS(ph)FSPNTGK ddPTM_PC-9_Lapatinib_30min_R1 1 LTFDSSFSPNTGK 13 0 P21796;C9JI87 P21796 VDAC1 Voltage-dependent anion-selective channel protein 1 1 LT(0.048)FDS(0.105)S(0.563)FS(0.28)PNT(0.003)GK 84.81700000000001 0.0083994 6402100.0 43023.0 70085.0 36635.0 24383.0 34032.0 33659.0 30580.0 30731.0 51039.0 19492.0 True False 42409.484130548066 69922.7224885096 33623.011715189554 26176.207159303573 32030.30466948632 32219.48303296129 32163.282770910835 32158.874449031147 45290.450355503155 22861.166228542603 1.8550883934170872 3.058580729849632 1.4707478778230736 1.1450075161354663 1.4010792078269336 1.4093543046257477 1.4068959758822086 1.4067031457424153 1.9811084833877444 1.0 14.48061138193031 -5.34640135073804 8.178627207742059 1.4054802927919194 2.45376829068732 0.5796581069738731 0.3592430926795249 0.18311594507570728 15.943859662393194 0.08788833496826201 0.18379696628574546 4.50400277335797e-06 5.34640135073804 1.0482879978954007 LTFDSS(ph)FSPNTGKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTFDSSFSPNTGKK 14 1 P21796;C9JI87 P21796 VDAC1 Voltage-dependent anion-selective channel protein 1 1 LTFDS(0.238)S(0.583)FS(0.178)PNT(0.002)GKK 140.03 0.00016462 16211000.0 145160.0 100020.0 99072.0 113860.0 161250.0 120530.0 116850.0 102250.0 114660.0 100130.0 True False 169732.72095931345 109949.32459084816 101434.25221265228 107480.79333910055 129654.22004281034 114209.19461906153 105781.12207926033 99566.04584283027 116336.6855845914 118282.77637135629 1.4349741032999326 0.9295463630787231 0.8575572481845793 0.9086766191694535 1.0961377811740967 0.9655606515397855 0.8943070607943271 0.8417628406881179 0.9835471330106843 1.0 16.851880486806962 -4.760894250352828 24.99945164566876 0.9373527594616526 1.4349746683889706 0.8129345133433415 0.07092807806799115 5.678558875055999 260183.83857070268 0.018722486787166842 0.10778063340399602 1.7342262262028474e-05 4.760894250352828 0.49762190892731795 LTFDSSFS(ph)PNTGK ddPTM_PC-9_AZD4547_30min_R2 1 LTFDSSFSPNTGK 13 0 P21796;C9JI87 P21796 VDAC1 Voltage-dependent anion-selective channel protein 1 1 LTFDS(0.013)S(0.206)FS(0.77)PNT(0.012)GK 68.262 0.03323 11849000.0 33746.0 44155.0 49623.0 35805.0 44172.0 32742.0 59632.0 62783.0 47273.0 40689.0 True False 44476.52603959524 58427.24025191345 48964.9665969078 27550.710431735584 38039.48026422077 30694.637564047167 64939.13247750891 53081.32995981505 49771.75427025773 39264.4904947677 1.1327417083260531 1.4880427458927383 1.2470546791746289 0.7016698824961687 0.9688010664315084 0.7817403760310468 1.6538895999723353 1.3518914747381874 1.2676021933072124 1.0 15.260937556023057 -7.258280955746371 24.99037197342506 1.347670096336795 1.0620781826137098 0.19992149823676386 0.2566930393795304 470.47176061545787 3722529.3828029754 0.10865311480210592 0.08049014210711082 5.5172040235242244e-08 7.258280955746371 -0.2855919137230851 LTFDSSFS(ph)PNTGKK ddPTM_PC-9_Lapatinib_30min_R1 2 LTFDSSFSPNTGKK 14 1 P21796;C9JI87 P21796 VDAC1 Voltage-dependent anion-selective channel protein 1 1 LTFDS(0.004)S(0.009)FS(0.932)PNT(0.055)GKK;LTFDS(0.042)S(0.105)FS(0.843)PNT(0.01)GKK 168.45 0.000516 28590000.0 507020.0 386120.0 175019.0 130950.0 148313.0 164821.0 112791.0 116773.0 234430.0 74150.0 True False 499789.8018239195 385225.96286314155 160629.6134128776 140580.499836394 139589.52093457695 157771.9900465168 118630.76608939856 122198.69988079497 208026.02474265976 86966.72870133552 5.746908148520991 4.429578628697181 1.8470237504795424 1.6164860048856264 1.6050910850511653 1.8141649387358632 1.3640936926212883 1.4051201155381436 2.3920185092516326 1.0 16.408175946967347 -5.1363407497800235 2.3669428265273273 1.6029196286607457 5.752326929895429 0.9438750222667278 0.34476236470814947 0.06617756635241326 0.6648744943574261 0.09071547629623372 0.40552768202449624 7.3056565282454516e-06 5.1363407497800235 4.1494073012346835 LTFDT(ph)TFSPNTGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTFDTTFSPNTGK 13 0 Q5JSD2;Q5JSD1;A0A0A0MR02;P45880-2;P45880;P45880-1 Q5JSD2 VDAC2 Voltage-dependent anion-selective channel protein 2 1 LT(0.008)FDT(0.704)T(0.067)FS(0.218)PNT(0.003)GK 78.486 0.036539 6519900.0 32460.0 30402.0 26018.0 19067.0 35784.0 17655.0 21349.0 17880.0 19938.0 20210.0 True False 37954.83688577643 33420.10964018162 26638.367793814472 17998.737806048037 28772.38207759336 16729.140720148775 19326.668166624986 17410.66894542596 20229.555531009817 23873.91301772802 1.589803768556598 1.399858901025772 1.1157939535941868 0.7539081587791133 1.2051808204305632 0.7007288963366097 0.8095308109849276 0.7292758808536055 0.8473498046167791 1.0 14.543147428105895 -5.137104813556153 1.0696727780546864 0.8378488490712946 1.7659066363955194 0.7521996728301558 0.14461506063158427 0.4981753660420539 0.6939492332920254 0.04762373688606704 0.4589794637083571 7.292814826661742e-06 5.137104813556153 0.9280577873242247 LTFDT(ph)TFSPNTGKK ddPTM_PC-9_AZD4547_30min_R2 1 LTFDTTFSPNTGKK 14 1 Q5JSD2;Q5JSD1;A0A0A0MR02;P45880-2;P45880;P45880-1 Q5JSD2 VDAC2 Voltage-dependent anion-selective channel protein 2 1 LT(0.016)FDT(0.687)T(0.147)FS(0.15)PNTGKK 197.06 3.0099999999999996e-47 0.0 37485.0 23307.0 51834.0 41364.0 37625.0 29970.0 41852.0 43144.0 44146.0 33432.0 True False 49404.4502635639 30840.5319567738 51146.64729226608 31828.16886742943 32401.41820477465 28095.97116225317 45576.74692193289 36477.086150490744 46479.46743415474 32261.555855908835 1.5313722154077474 0.9559530263982985 1.5853744785497803 0.986566457290062 1.004335263602614 0.870880849260321 1.412726253051597 1.1306672968101696 1.440707560470672 1.0 14.977528395584175 -4.739365353762074 24.53909730503142 1.1610057752115452 1.5313740430050218 0.19418519443516724 0.23015695846548637 2474.526425004351 2750684.918321178 0.05618189038437313 2.734677987392488 1.8223619804571248e-05 4.739365353762074 0.37036826779347654 LTFDTT(ph)FSPNTGKK ddPTM_PC-9_AZD4547_30min_R2 1 LTFDTTFSPNTGKK 14 1 Q5JSD2;Q5JSD1;A0A0A0MR02;P45880-2;P45880;P45880-1 Q5JSD2 VDAC2 Voltage-dependent anion-selective channel protein 2 1 LTFDT(0.114)T(0.443)FS(0.443)PNTGKK 82.94200000000001 0.0073435 37222000.0 67337.0 58382.0 100960.0 79419.0 80543.0 57861.0 94996.0 81860.0 82625.0 63760.0 True False 88748.7653033908 77252.83977776482 99621.20443390799 61110.176561318454 69360.99472337979 54242.94252316085 103450.45996836312 69210.41795566412 86992.38881771927 61527.78180703357 1.4424177614874694 1.2555765462185675 1.6191255642263338 0.9932127368572325 1.1273118042986356 0.8816008139750626 1.6813617674826877 1.124864507105509 1.4138716895491055 1.0 15.908950361139599 -5.762167546920334 24.999998683006723 1.1867420510656104 1.4206935850149651 0.21265090187916602 0.23154820468373138 34.21988936339281 1174939.458344175 0.06397926873304495 0.10159487150496818 1.729149140272724e-06 5.762167546920334 0.23395153394935475 LTFDTTFS(ph)PNTGK ddPTM_PC-9_AZD4547_30min_R2 2 LTFDTTFSPNTGK 13 0 Q5JSD2;Q5JSD1;A0A0A0MR02;P45880-2;P45880;P45880-1 Q5JSD2 VDAC2 Voltage-dependent anion-selective channel protein 2 1 LTFDT(0.077)T(0.007)FS(0.842)PNT(0.074)GK;LTFDTT(0.005)FS(0.994)PNTGK 146.27 0.0001028 15210900.0 73888.0 90868.0 112792.0 83712.0 83832.0 82481.0 117987.0 121085.0 110794.0 77981.0 True False 97382.84703412605 120239.30397941056 111296.3043830165 64413.49173750735 72193.37384565221 77323.45003115808 128487.61442889457 102374.09550649382 116650.34464956605 75250.90892556922 1.2941085818703872 1.597845204744828 1.4790027917549784 0.8559829064818183 0.9593687953597846 1.0275417418231958 1.7074559797806808 1.3604366640641135 1.5501519691269785 1.0 16.199421387262213 -7.2461099255371915 24.889220420162214 1.4345475778339212 1.206079550816503 0.11410010650366542 0.2707754813734227 1692.5100559360753 2747998.3151394986 0.11194480186285023 0.08638753449068336 5.6740097072439606e-08 7.2461099255371915 -0.2284680270174182 LTFDTTFS(ph)PNTGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTFDTTFSPNTGK 13 0 Q5JSD2;Q5JSD1;A0A0A0MR02;P45880-2;P45880;P45880-1 Q5JSD2 VDAC2 Voltage-dependent anion-selective channel protein 2 1 LTFDTT(0.002)FS(0.998)PNTGK 219.84 8.4151e-15 6163300.0 49709.0 56533.0 44654.0 33640.0 59143.0 26934.0 36573.0 23709.0 29864.0 28623.0 True False 58123.751902497235 62145.22262641888 45718.72071123804 31755.259862351526 47554.353711577896 25521.53362540283 33108.540674409815 23086.663871761975 30300.704502862744 33812.12332045668 1.7190210550111111 1.8379568191394944 1.3521398901197592 0.9391678706891284 1.4064290864220002 0.7548042275701166 0.9791914089695398 0.6827924899290281 0.8961491183409505 1.0 15.045252996422768 -5.435165626567758 0.7403576020695286 0.8595079687337828 2.0381046035964134 0.7522083266429083 0.18878243444874385 0.6361557816013854 0.4773037935944243 0.08562887485078002 0.5412969105778556 3.6714225702259304e-06 5.435165626567758 1.1785966348626307 LTFDTTFS(ph)PNTGK ddPTM_PC-9_Lapatinib_30min_R1 2 LTFDTTFSPNTGK 13 0 Q5JSD2;Q5JSD1;A0A0A0MR02;P45880-2;P45880;P45880-1 Q5JSD2 VDAC2 Voltage-dependent anion-selective channel protein 2 1 LTFDT(0.051)T(0.216)FS(0.706)PNT(0.027)GK;LTFDTT(0.003)FS(0.85)PNT(0.147)GK 156.96 0.00021732 10299300.0 151885.0 209529.0 79985.0 72361.0 71962.0 87312.0 79306.0 68938.0 126974.0 44419.0 True False 149719.09204770238 209043.84847392337 73408.94205102872 77682.66932921973 67729.33664273554 83577.86929421303 83412.07663276182 72141.11115054214 112672.85102450392 52096.76496540292 2.8738654338158947 4.012607090147495 1.4090883013518989 1.4911227094582211 1.3000679924696685 1.6042813666014861 1.6010989682018675 1.3847522240286998 2.162760991000672 1.0 15.668906168305151 -5.270056346603756 24.980003049763457 1.5086013990022151 3.4432362789284245 0.8103971102893818 0.3770557828594077 199.82199092345513 579271.3883794318 0.09110783568044081 0.19450353670168521 5.369621248543204e-06 5.270056346603756 1.9346348799262094 LTFDTTFS(ph)PNTGKK ddPTM_PC-9_AZD4547_30min_R2 1 LTFDTTFSPNTGKK 14 1 Q5JSD2;Q5JSD1;A0A0A0MR02;P45880-2;P45880;P45880-1 Q5JSD2 VDAC2 Voltage-dependent anion-selective channel protein 2 1 LTFDT(0.033)T(0.025)FS(0.94)PNT(0.002)GKK 103.76 0.0016646 10714000.0 20315.0 13719.0 23684.0 25020.0 22756.0 15954.0 26062.0 23728.0 25341.0 21125.0 True False 26774.747421750053 18153.39846033294 23369.934685149317 19252.025555146618 19596.72219715221 14956.393857944178 28381.467511216077 20061.38281519665 26680.47352532316 20385.420179949557 1.3134263206448318 0.8905089176522365 1.1464043654167715 0.9444017040218916 0.9613106830354624 0.7336809212622856 1.3922434397075207 0.9841044549539568 1.3088017460422627 1.0 14.315250073206036 -7.269579479485444 24.999949566680336 1.1699627542888933 0.9959920160345931 0.17463175709750534 0.18420158219837565 1116.1482535547864 3427910.5014036545 0.07262482476572482 0.049916636872383215 5.3755204764507056e-08 7.269579479485444 -0.1739707382543002 LTFDTTFS(ph)PNTGKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LTFDTTFSPNTGKK 14 1 Q5JSD2;Q5JSD1;A0A0A0MR02;P45880-2;P45880;P45880-1 Q5JSD2 VDAC2 Voltage-dependent anion-selective channel protein 2 1 LTFDT(0.095)T(0.024)FS(0.877)PNT(0.004)GKK;LTFDTT(0.027)FS(0.973)PNTGKK 198.81 1.0545e-07 15516500.0 118767.0 82830.0 88801.0 78854.0 146501.0 92982.0 100191.0 88817.0 88576.0 80174.0 True False 138871.9073448246 91052.8149956002 90918.35261966806 74436.06602811714 117795.18071622816 88105.86023454393 90700.1831599758 86485.64785939026 89871.25643067127 94708.91154296526 1.4663024321826836 0.9613964885901318 0.9599767449383304 0.7859457448663506 1.243760262863856 0.9302805702140731 0.9576731659388686 0.9131732848619586 0.9489208034019126 1.0 16.531212560617526 -4.761158648835195 24.999998247905527 0.9654434359893953 1.4663029798231553 0.660877561760886 0.10734154391333518 4.004235342160791 355974.6769895826 0.02614657032640201 0.1481416576058132 1.7331707505885865e-05 4.761158648835195 0.50085954383376 LTFS(ph)TLELR ddPTM_PC-9_AZD4547_30min_R2 1 LTFSTLELR 9 0 Q3KR16-3;Q3KR16-2;Q3KR16 Q3KR16-3 PLEKHG6 Pleckstrin homology domain-containing family G member 6 1 LT(0.147)FS(0.708)T(0.145)LELR 76.943 0.023778999999999998 3629500.0 4225.5 2584.6 6757.4 12581.0 7069.4 7735.5 6300.1 8773.9 3986.4 8580.1 True False 5569.121104140035 3420.0214053922678 6667.792460793277 9680.644824512372 6087.935836726482 7251.79796214913 6860.796695089114 7418.095359164438 4197.112965603101 8279.713310579184 0.6726224562659964 0.413060365389998 0.8053168280927895 1.169200485739426 0.7352834099880952 0.8758513356837293 0.828627325335397 0.8959362578032942 0.5069152527588547 1.0 13.015365099178203 -5.3780242767446484 6.186269416800483 0.8584066218579598 0.5458446033374748 0.3462082851840832 0.17099066270145113 0.23506228214505626 10.965823907521527 0.043844447265224164 0.09263007559490471 4.187701555175036e-06 5.3780242767446484 -0.31256201852048504 LTFS(ph)TLELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTFSTLELR 9 0 Q3KR16-3;Q3KR16-2;Q3KR16 Q3KR16-3 PLEKHG6 Pleckstrin homology domain-containing family G member 6 1 LTFS(0.954)T(0.046)LELR 126.03 0.0014077 1516100.0 2593.9 4154.5 5201.7 5812.0 5961.5 5798.8 6302.6 4847.3 5385.1 4093.8 True False 3032.996038139727 4566.931303866016 5325.728255557106 5486.372482758235 4793.386869985823 5494.700719796022 5705.572101127479 4720.063511138883 5463.846899891712 4835.973533497033 0.6271738290400608 0.9443664801373582 1.1012732428471166 1.134491833910199 0.9911937765547666 1.136213976717661 1.179818719355483 0.9760317087024395 1.129833912871034 1.0 12.239590633633519 -4.787762815114343 2.3155291979534054 1.08422244664603 0.5179486496465115 0.8086321048661433 0.06691494450405047 0.23257149027499027 1.5177316889827221 0.017173782053019015 0.2705094566819634 1.6301860967657508e-05 4.787762815114343 -0.5662737969995184 LTFS(ph)TLELR ddPTM_PC-9_Lapatinib_30min_R1 3 LTFSTLELR 9 0 Q3KR16-3;Q3KR16-2;Q3KR16 Q3KR16-3 PLEKHG6 Pleckstrin homology domain-containing family G member 6 1 LT(0.167)FS(0.666)T(0.167)LELR;LT(0.058)FS(0.743)T(0.199)LELR;LT(0.002)FS(0.956)T(0.042)LELR 141.91 0.0006911 5094900.0 23453.199999999997 19411.4 22508.5 16365.5 17234.0 20333.8 15108.0 15439.599999999999 16951.3 12284.8 True False 23118.75306720988 19366.454095932873 20657.938015322612 17569.0734637076 16220.330003347648 19464.17077440291 15890.218315988259 16156.980181030929 15042.06608889752 14408.211311532945 1.6045539982263202 1.344126184520291 1.4337614550938131 1.2193792195180095 1.1257698580783728 1.350908197662465 1.1028585000880056 1.1213730720410933 1.0439926069696945 1.0 13.81460362469758 -1.5228787455865869 0.21334494546742633 0.99114815653633 3.9193055632259943 0.7995893283407526 0.08202002272954993 22.48313774229381 0.28247930889852985 0.13412716971666716 22.446870228405928 0.029999999978845046 1.5228787455865869 2.9281574066896643 LTFSCLGGSDNFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTFSCLGGSDNFK 13 0 A0A087WYT3;Q15185-4;Q15185;Q15185-3;Q15185-2 A0A087WYT3 PTGES3 Prostaglandin E synthase 3 0 172.92 0.0009243000000000001 2748600.0 15903.0 12363.0 13969.0 16463.0 19560.0 15541.0 16227.0 20881.0 15840.0 9248.6 False True 18595.063801432625 13590.316935779409 14302.073937727511 15540.631483766143 15727.35841263487 14726.002601633092 14689.861086693689 20332.8958752483 16071.63003366413 10925.29796812269 1.7020189157026573 1.2439310099763488 1.3090786154718541 1.4224446352959756 1.439535878886178 1.347881096204416 1.3445730386077397 1.8610838747441625 1.4710472959691498 1.0 13.415385006760067 LTFSCLGGSDNFK ddPTM_PC-9_Lapatinib_30min_R1 2 LTFSCLGGSDNFK 13 0 A0A087WYT3;Q15185-4;Q15185;Q15185-3;Q15185-2 A0A087WYT3 PTGES3 Prostaglandin E synthase 3 0 ; 178.95 0.00053953 21786000.0 48222.0 44274.0 44726.0 45444.0 42662.0 44794.0 41364.0 34456.0 42695.0 37031.0 False True 47534.34543716824 44171.48627318643 41048.80092735276 48786.10335673998 40152.70503671912 42878.26503991408 43505.62552439358 36056.95154781221 37886.23950171844 43431.75900929413 1.0944605174060802 1.0170319434617878 0.9451332818127067 1.1232817751245132 0.9245010092298285 0.9872560084600394 1.0017007488709735 0.8301978176867357 0.8723164883469494 1.0 15.40646276343947 -7.085420540606802 1.0392368131402716 0.8996772436743407 1.031122610608422 0.3211952978081648 0.07099688471779453 0.6014568253981127 1.3147369875365054 0.04644594205219638 0.030802166806555505 8.214468326535089e-08 7.085420540606802 0.13144536693408126 LTFST(ph)LELR ddPTM_PC-9_AZD4547_30min_R2 1 LTFSTLELR 9 0 Q3KR16-3;Q3KR16-2;Q3KR16 Q3KR16-3 PLEKHG6 Pleckstrin homology domain-containing family G member 6 1 LT(0.004)FS(0.402)T(0.594)LELR 97.81299999999999 0.011401 508040.0 2809.9 2604.4 4380.1 6040.4 3637.1 3548.7 3540.8 3957.4 1168.2 3114.0 True False 3703.3897504492006 3446.2213681821636 4322.0170120935045 4647.879103249703 3132.151445915905 3326.799228010938 3855.924340561503 3345.874762005193 1229.948667072433 3004.9798078278336 1.2324175160185906 1.146836780468513 1.4382848766021155 1.546725569051144 1.0423202970471865 1.1070953686093927 1.2831781200382772 1.1134433427104382 0.4093034714803985 1.0 11.553139581340803 -8.07588876060539 5.930078639382786 0.7097901092046829 1.2531817315972242 0.5586315293471882 0.19342766141616952 0.16771506994900878 10.072243012678836 0.13374946902524 0.04974849267993853 8.39675031805108e-09 8.07588876060539 0.5433916223925414 LTGMAFR ddPTM_PC-9_AZD4547_30min_R2 1 LTGMAFR 7 0 P04406;P04406-2;E7EUT5;O14556 P04406 GAPDH;GAPDHS Glyceraldehyde-3-phosphate dehydrogenase;Glyceraldehyde-3-phosphate dehydrogenase, testis-specific 0 110.34 0.043677999999999995 20075000.0 33142.0 27597.0 41221.0 52521.0 49742.0 39086.0 32727.0 38438.0 32808.0 36286.0 False True 43680.466603575675 36517.190561251424 40674.38260667704 40413.09489136112 42836.1819094193 36641.94624116874 35639.639599400216 32498.29031736887 34542.16390114054 35015.63818459881 1.2474559616276817 1.0428823364217037 1.1616062055543845 1.1541441763336564 1.223344315005524 1.0464451925164466 1.0178206494912856 0.9281078969928024 0.9864782049391144 1.0 15.095711761397162 -7.0333707644366354 2.822552686599976 0.9766277450389085 1.1577711045728298 0.7003943205836285 0.05617512948684347 0.15403393345836625 2.45580745819253 0.022590827675361344 0.01779509219995107 9.260389109692776e-08 7.0333707644366354 0.18114335953392136 LTGMAFR ddPTM_PC-9_Lapatinib_30min_R1 1 LTGMAFR 7 0 P04406;P04406-2;E7EUT5;O14556 P04406 GAPDH;GAPDHS Glyceraldehyde-3-phosphate dehydrogenase;Glyceraldehyde-3-phosphate dehydrogenase, testis-specific 0 110.34 0.043677999999999995 51236000.0 50916.0 51673.0 62212.0 50944.0 44666.0 50539.0 45871.0 39646.0 46596.0 50857.0 False True 50189.92850314912 51553.35434327964 57097.1695052647 54690.591704202154 42038.83369673473 48377.56478216314 48245.97593147324 41488.09789483874 41347.86780236728 59647.56468730716 0.8414413692539137 0.8642993995402809 0.9572422579964077 0.9168956350675649 0.7047870926016276 0.8110568308324876 0.8088507248266558 0.6955539276805931 0.6932029500135819 1.0 15.864175615789023 -6.246896918544673 24.48464756412891 0.7727908020872949 0.8972269845059453 0.2585396409598816 0.08916156628731185 755.1117016133967 1271355.1559104444 0.025605680785382338 0.03289986147720576 5.663737040492272e-07 6.246896918544673 0.1244361824186504 LTGS(ph)LGCSIDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTGSLGCSIDR 11 0 Q99698 Q99698 LYST Lysosomal-trafficking regulator 1 LT(0.004)GS(0.962)LGCS(0.034)IDR 67.51899999999999 0.039502999999999996 2124500.0 15557.0 13155.0 12837.0 11948.0 14874.0 14511.0 16281.0 14152.0 13382.0 11446.0 True False 18190.492835244117 14460.94146163375 13143.082764593602 11278.592295938646 11959.546473902406 13750.017614844455 14738.745815767548 13780.524995283451 13577.68643374327 13521.069193513858 1.3453442604945924 1.069511682446737 0.9720446346727093 0.8341494399976193 0.8845118904974968 1.0169327157530135 1.0900577169472527 1.0191890003709214 1.0041873345531411 1.0 13.722921618387767 -4.772896723597606 2.561048189069562 0.9761012828133195 1.428649609757391 0.7241920726329751 0.06825983154235911 0.31381697506476136 2.6000262540850567 0.02065050357862309 0.3161180835377587 1.686954139950821e-05 4.772896723597606 0.45254832694407154 LTGS(ph)QLSITQVASIK ddPTM_PC-9_AZD4547_30min_R2 2 LTGSQLSITQVASIK 15 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 LT(0.007)GS(0.987)QLS(0.005)IT(0.001)QVASIK;LT(0.001)GS(0.997)QLS(0.001)IT(0.001)QVASIK 88.427 0.0048519 17578800.0 49536.0 49438.0 76808.0 96562.0 74792.0 83480.0 75727.0 94667.0 82352.0 93048.0 True False 65287.417587192234 65417.86668721771 75789.4757345443 74301.12276802835 64408.42180389392 78259.98240323315 82466.55629736229 80038.39038124653 86704.95859505983 89790.41784160679 0.7271089628111694 0.728561780418674 0.8440708658716725 0.8274950106491089 0.717319546474463 0.8715850119027879 0.9184338182147228 0.8913912230861522 0.965637098916392 1.0 16.4542738727341 -7.3575740291487834 0.4723669222339729 1.0074552282974423 0.7403281723917838 0.7712954517367969 0.045550659564509474 0.5042440253801118 0.25205733036968353 0.048900544131209506 0.04443325138387122 4.389610346613733e-08 7.3575740291487834 -0.26712705590565844 LTGS(ph)QLSITQVASIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTGSQLSITQVASIK 15 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 LT(0.006)GS(0.994)QLSITQVASIK 137.73 4.4478000000000003e-05 7420000.0 13479.0 14295.0 30039.0 30226.0 30254.0 28208.0 27772.0 25881.0 27920.0 22757.0 True False 15760.728477614926 15714.113127636221 30755.243683541907 28532.535214014184 24325.9458801562 26728.72282265402 25141.235108131932 25201.65117318622 28328.2771805494 26882.66395568713 0.5862785214885924 0.5845444913323719 1.14405490967109 1.0613730566675486 0.9048934257503134 0.9942735908432713 0.9352211205546542 0.9374685192928848 1.053774924510651 1.0 14.714388489586758 -5.2485224317254175 24.87771000237617 0.9973717249919385 0.5854114131018001 0.8619657381494072 0.06694385990325298 253.1607265679562 487578.86958968756 0.018002623834260618 0.04696077766221937 5.642577961375062e-06 5.2485224317254175 -0.4119603118901384 LTGS(ph)TSSLNK ddPTM_PC-9_AZD4547_30min_R2 4 LTGSTSSLNK 10 0 Q9NV70-2;Q9NV70 Q9NV70-2 EXOC1 Exocyst complex component 1 1 LT(0.01)GS(0.973)T(0.012)S(0.003)S(0.002)LNK;LT(0.001)GS(0.818)T(0.044)S(0.105)S(0.031)LNK;LT(0.001)GS(0.883)T(0.065)S(0.016)S(0.035)LNK;LT(0.013)GS(0.959)T(0.015)S(0.004)S(0.008)LNK 132.32 0.00015032 113174000.0 157871.0 161723.0 247480.0 331597.0 283223.0 261753.0 248461.0 262238.0 231350.0 268435.0 True False 208070.6940792074 213996.79708436632 244198.25349944082 255152.43477257976 243902.3752348413 245385.54353130687 270573.54766726436 221715.14272975098 243578.6886896143 259037.1723552551 0.803246469174123 0.8261238923303316 0.9427150986829661 0.985003165579079 0.94157287549581 0.9472985722480564 1.0445355977565558 0.8559201782270884 0.9403232998372899 1.0 17.982799616844822 -5.250225980894797 3.7366516991233367 0.9562566163710561 0.8084423635867032 0.6079452811253259 0.0460426153123248 0.14678366729518458 4.594392116191096 0.01218218941957999 0.03334665833314211 5.620487924852977e-06 5.250225980894797 -0.1478142527843529 LTGS(ph)TSSLNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LTGSTSSLNK 10 0 Q9NV70-2;Q9NV70 Q9NV70-2 EXOC1 Exocyst complex component 1 1 LT(0.003)GS(0.355)T(0.214)S(0.214)S(0.214)LNK;LT(0.006)GS(0.959)T(0.021)S(0.01)S(0.003)LNK;LTGS(0.978)T(0.014)S(0.004)S(0.004)LNK;LT(0.003)GS(0.544)T(0.28)S(0.127)S(0.046)LNK;LT(0.002)GS(0.936)T(0.016)S(0.03)S(0.016)LNK;LT(0.002)GS(0.722)T(0.119)S(0.048)S(0.108)LNK 114.71 0.001185 111613100.0 192532.0 212185.0 235998.0 286863.0 334874.0 267789.0 285371.0 260533.0 267560.0 220838.0 True False 225123.8649196645 233249.324518188 241625.08734739939 270790.99613239366 269257.8436131226 253745.6734244082 258338.592972876 253694.28480753087 271472.5588262099 260874.1812473538 0.8629595456447574 0.8941065896322923 0.9262131123596975 1.0380137844137094 1.0321368037483927 0.9726745368634754 0.990280416933734 0.9724775506510737 1.040626395177095 1.0 17.992994641936015 -5.559634606746452 3.6529977161090907 1.0042367667993193 0.8824563084826624 0.8161590247467542 0.024944992827979778 0.09544497690435412 2.682522516710395 0.00733323231290383 0.014334222701305499 2.756546946154119e-06 5.559634606746452 -0.12178045831665685 LTGS(ph)TSSLNK ddPTM_PC-9_Lapatinib_30min_R1 2 LTGSTSSLNK 10 0 Q9NV70-2;Q9NV70 Q9NV70-2 EXOC1 Exocyst complex component 1 1 LTGS(0.683)T(0.225)S(0.054)S(0.038)LNK;LTGS(0.386)T(0.098)S(0.339)S(0.177)LNK 166.86 0.00014769 47184000.0 314093.0 300114.0 297393.0 264583.0 305001.0 288993.0 271940.0 255190.0 279077.0 215078.0 True False 309613.976222398 299419.10447194905 272942.4955101785 284041.31644301384 287061.44083503744 276633.44306558673 286019.72258736094 267047.0590168975 247644.40944890663 252253.94572657917 1.227390022901731 1.1869749097859215 1.082014771757124 1.1260133736456568 1.1379859292515746 1.0966466441933589 1.1338562882079983 1.0586437339868324 0.9817266038618525 1.0 17.94451731041125 -1.5228787452803474 0.12332954864020829 0.9439642796091231 1.7989321094021307 0.730242510246492 0.03780968021949368 52.32410909415875 0.442994927488309 0.2590122785369609 7.711694795132547 0.029999999999999322 1.5228787452803474 0.8549678297930076 LTGST(ph)SSLNK ddPTM_PC-9_AZD4547_30min_R2 3 LTGSTSSLNK 10 0 Q9NV70-2;Q9NV70 Q9NV70-2 EXOC1 Exocyst complex component 1 1 LTGS(0.003)T(0.332)S(0.332)S(0.332)LNK;LTGS(0.044)T(0.401)S(0.401)S(0.154)LNK;LTGS(0.074)T(0.394)S(0.394)S(0.137)LNK 162.26 0.00082435 74169500.0 215979.0 225083.0 338528.0 379641.0 363672.0 350787.0 291706.0 309016.0 280705.0 336608.0 True False 284655.82935772376 297836.67801203596 334038.8975297341 292120.6328449805 313182.4202356622 328852.23343654734 317667.26889059914 261264.67768125405 295542.4932293845 324823.4563755006 0.8763401280622343 0.9169186281539116 1.0283706147858371 0.8993212377719572 0.9641619596388348 1.0124029745450076 0.9779689940968155 0.8043282360102354 0.9098557614254714 1.0 18.30929629161116 -10.537528234515094 4.6539791386610565 1.0000017003655137 0.9344846543651425 0.09251880890398212 0.06334868674575657 1.1762753335521425e-06 2.490629248582573e-07 0.06455279952974098 0.015655947182750752 2.9004926246533682e-11 10.537528234515094 -0.06551704600037123 LTGST(ph)SSLNK ddPTM_PC-9_Lapatinib_30min_R1 2 LTGSTSSLNK 10 0 Q9NV70-2;Q9NV70 Q9NV70-2 EXOC1 Exocyst complex component 1 1 LTGS(0.149)T(0.33)S(0.33)S(0.191)LNK;LT(0.008)GS(0.22)T(0.413)S(0.122)S(0.237)LNK 141.71 0.00030681 73894000.0 186081.0 183527.0 183965.0 180980.0 178609.0 177484.0 144159.0 163291.0 186609.0 119171.0 True False 183427.450816924 183102.0545073651 168840.1078254358 194289.8729315819 168103.56977880473 169893.4230554116 151622.84764459575 170878.09598310338 165591.1293401143 139769.54856462407 1.3123563229662591 1.31002823138336 1.207989219106411 1.3900729803226755 1.202719558767696 1.2155253043323626 1.0848060196351794 1.2225702789910344 1.1847439663407893 1.0 17.092690551028703 -6.696972953868111 1.9959051530163472 1.144073560186324 1.2977273311610709 0.5213102066008366 0.07370027871622559 0.2851874164290403 2.336409564221592 0.02780203678619537 0.026690390853811488 2.009217934809145e-07 6.696972953868111 0.15365377097474697 LTGSTS(ph)SLNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LTGSTSSLNK 10 0 Q9NV70-2;Q9NV70 Q9NV70-2 EXOC1 Exocyst complex component 1 1 LTGS(0.002)T(0.196)S(0.644)S(0.159)LNK;LTGS(0.001)T(0.11)S(0.667)S(0.221)LNK 180.66 0.00012641 56300000.0 328990.0 346530.0 337450.0 477320.0 512570.0 423660.0 472490.0 371310.0 367100.0 386800.0 True False 384681.5091513112 380931.2082630134 345496.0877862524 450577.30789232 412135.5880145327 401442.5237891945 427732.3266686325 361563.5059354642 372468.1430150322 456923.7780928839 0.8418942668225788 0.8336865502008901 0.7561350587362508 0.9861104400671532 0.901978859000753 0.8785765657999723 0.9361130831358982 0.7912993879297857 0.8151647186531767 1.0 18.80159399609036 -5.744552943080209 24.99986752509714 0.8931540681369063 0.8128834465618829 0.2803946821273454 0.06568433668791321 373.02330716738976 552245.4941480207 0.018250371739896284 0.03150516799869044 1.8007236021445619e-06 5.744552943080209 -0.0802706215750234 LTGSTSS(ph)LNK ddPTM_PC-9_Lapatinib_30min_R1 1 LTGSTSSLNK 10 0 Q9NV70-2;Q9NV70 Q9NV70-2 EXOC1 Exocyst complex component 1 1 LTGS(0.099)T(0.099)S(0.231)S(0.571)LNK 112.83 0.0013942 12629000.0 77695.0 55031.0 52976.0 48479.0 49344.0 51711.0 33498.0 41273.0 57449.0 35777.0 True False 76587.05505248181 54903.57910059455 48620.517773273714 52044.30738120321 46441.6829340366 49499.44107422862 35232.36253302717 43190.694254494214 50978.48865521073 41961.00678014409 1.825195840837707 1.3084428452411412 1.1587071308375017 1.24030168422533 1.1067819029550254 1.1796533227522965 0.8396453096949783 1.0293054807000488 1.2149014660757307 1.0 15.356761672795807 -1.5228787581194312 0.7525570311829404 1.0638912475936901 135.48145136819466 0.8141269128687685 0.10677190703205114 160.14441293787516 0.6844552558469166 0.04115069112148977 36504.01508353855 0.029999999113106846 1.5228787581194312 134.41756012060097 LTGVFAPR ddPTM_PC-9_Lapatinib_30min_R1 1 LTGVFAPR 8 0 P62701;C9JEH7;Q8TD47;P22090 P62701 RPS4X;RPS4Y1;RPS4Y2 40S ribosomal protein S4, X isoform;40S ribosomal protein S4, Y isoform 2;40S ribosomal protein S4, Y isoform 1 0 99.375 0.024045 4159000.0 23143.0 19836.0 19830.0 22962.0 22230.0 23168.0 25443.0 21839.0 20526.0 19982.0 False True 22812.97657609358 19790.070960720208 18199.65394601362 24650.702078986527 20922.47510586156 22177.158647245815 26760.31404644488 22853.719667189187 18214.145731637713 23435.862075658624 0.9734216945997478 0.8444353741642355 0.7765728389789626 1.0518367960779937 0.8927546611392817 0.9462915669861299 1.1418531974652282 0.975160187980707 0.7771911983794961 1.0 14.516430244108339 -5.763255431601641 24.999995807962215 0.9713050952863268 0.8627725193657401 0.1848937356797563 0.10044711878723056 81.13082757337997 1116884.5896177469 0.028648856383912038 0.045098232621046404 1.7248231337054086e-06 5.763255431601641 -0.10853257592058674 LTHDDTGAR ddPTM_PC-9_Lapatinib_30min_R1 1 LTHDDTGAR 9 0 Q5JRX3-3;Q5JRX3;Q5JRX3-2 Q5JRX3-3 PITRM1 Presequence protease, mitochondrial 0 79.48899999999999 0.016357 0.0 12240.0 10115.0 6061.5 4925.3 7329.3 4005.5 5320.6 4416.3 8240.8 4682.3 False True 12065.455355458911 10091.57933896375 5563.146868066647 5287.52299231915 6898.204983958218 3834.1941022765513 5596.074634104256 4621.497420495795 7312.634324528892 5491.629316227424 2.19706295903954 1.837629373334387 1.0130230115182561 0.962833193546922 1.2561308469190464 0.698188803630053 1.0190190036257913 0.8415530536337471 1.3315964904842559 1.0 12.423018531835208 -5.148508075597548 2.8445205384639647 0.9992365204204777 2.163548672228844 0.8456891860730855 0.17404234910220517 0.0945929646846426 1.418902333101192 0.04484048817191932 0.16760838940558978 7.103819605048046e-06 5.148508075597548 1.1643121518083666 up LTIAEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTIAEER 7 0 P62701;Q8TD47 P62701 RPS4X;RPS4Y2 40S ribosomal protein S4, X isoform;40S ribosomal protein S4, Y isoform 2 0 100.19 0.015778999999999998 0.0 19826.0 20398.0 26363.0 27855.0 30500.0 27439.0 26281.0 25777.0 25137.0 20293.0 False True 23182.15021865076 22422.97863431434 26991.593902234257 26294.374657128457 24523.743946081973 26000.050536401162 23791.473422037154 25100.38106298909 25504.58107046814 23971.96026070039 0.9670527552415292 0.9353836061156229 1.125965236413488 1.0968804541293784 1.0230178791963949 1.0846026046115895 0.9924709186607853 1.0470725293224614 1.063933895814116 1.0 14.549060266957799 -5.241020430144012 24.993159263723925 1.0552098210040206 0.9512181587248595 0.510587070933024 0.04033747447317563 647.4960923410097 792544.370421735 0.010353084247985526 0.027325040310073177 5.740894551726767e-06 5.241020430144012 -0.10399166227916112 LTIAEER ddPTM_PC-9_Lapatinib_30min_R1 1 LTIAEER 7 0 P62701;Q8TD47 P62701 RPS4X;RPS4Y2 40S ribosomal protein S4, X isoform;40S ribosomal protein S4, Y isoform 2 0 111.65 0.042787 6493300.0 61143.0 71571.0 63960.0 57071.0 65192.0 67540.0 52254.0 50144.0 63757.0 52862.0 False True 60271.08960774706 71405.28174680912 58701.45569273983 61268.19172327499 61357.53473240336 64651.471643429875 54959.456439214395 52473.87329967191 56576.015269025884 61999.12626581256 0.9721280482138283 1.1517143232094753 0.9468110153853712 0.9882105670424485 0.9896516036265016 1.0427803670368798 0.8864553381540158 0.8463647225397586 0.9125292351131554 1.0 15.919960263744747 -7.265845855141624 24.950480317676544 0.8985343779278091 1.0159216049156663 0.3829278763355741 0.06377454541171788 352.23426437768893 1994419.5710892968 0.02565876906270494 0.017971327362495598 5.421932978173345e-08 7.265845855141624 0.1173872269878572 LTIFGNSAVSQPASSSNHS(ph)SR ddPTM_PC-9_AZD4547_30min_R2 1 LTIFGNSAVSQPASSSNHSSR 21 0 P46934-3;P46934-2;P46934;H0Y8X6;P46934-4 P46934-3 NEDD4 E3 ubiquitin-protein ligase NEDD4 1 LTIFGNSAVSQPAS(0.085)S(0.147)S(0.147)NHS(0.369)S(0.252)R 78.484 0.00062088 4046100.0 9186.4 6575.8 26750.0 82720.0 50895.0 33103.0 24498.0 56422.0 23936.0 40974.0 True False 12107.484111009828 8701.29875322234 26395.277521860487 63650.182011260134 43829.10776164802 31033.064176979184 26678.27454108553 47703.276348576575 25201.208093687514 39539.51273151497 0.30621227411736807 0.22006590754688204 0.6675670917113282 1.6097867073745638 1.1084888187484927 0.7848620793003419 0.6747244135819006 1.2064710223541697 0.6373676950652173 1.0 15.27100747155338 -5.521764104873146 24.999601037638037 1.0045001081926628 0.30830832468422437 0.5491396833208047 0.26787463841980125 30.075289243343132 674539.8559530966 0.07579882791885956 0.1335227947958207 3.007709552417699e-06 5.521764104873146 -0.6961917835084384 LTLEDLEDSWDR ddPTM_PC-9_AZD4547_30min_R2 2 LTLEDLEDSWDR 12 0 Q6P2Q9;I3L3Z8 Q6P2Q9 PRPF8 Pre-mRNA-processing-splicing factor 8 0 ; 143.96 0.00029264 1897230.0 9119.8 9067.0 12323.900000000001 16797.1 12304.1 13441.3 10033.0 11886.2 11498.6 13430.8 False True 12019.706696375892 11997.730435151158 12160.477033706795 12924.788107608041 10595.88809922572 12600.813386159276 10925.91756350361 10049.460907703578 12106.392521142841 12960.591780017363 0.9274041571857754 0.9257085354427453 0.9382655699761963 0.9972374970975844 0.8175466274281131 0.9722405890128571 0.8430107011277977 0.7753859606316614 0.9340925728259164 1.0 13.66184397266433 -6.2553735920154345 24.988282529550833 0.8808733303959332 0.9449872378988914 0.136475329542053 0.06737875798186949 887.2271535756017 3654968.5611636993 0.019713089135216844 0.024774206628044606 5.554262588165703e-07 6.2553735920154345 0.0641139075029582 LTLEDLEDSWDR ddPTM_PC-9_Lapatinib_30min_R1 2 LTLEDLEDSWDR 12 0 Q6P2Q9;I3L3Z8 Q6P2Q9 PRPF8 Pre-mRNA-processing-splicing factor 8 0 ; 124.67 0.0014542 935640.0 10816.2 12637.2 13353.7 10530.7 13117.8 12795.5 11232.3 10817.6 12312.2 11558.0 False True 10661.959004551847 12607.939339827253 12255.810332772668 11305.162807385386 12346.23679458708 12248.266292767346 11813.853533934 11320.225187590353 10925.470382786214 13555.784899933073 0.7865246522615217 0.9300781498745603 0.9041018593348421 0.8339733103496797 0.9107725510345059 0.9035453412091112 0.8714990405308309 0.8350844507459131 0.8059636873435603 1.0 13.726621029313597 -11.800436340072686 2.349005190649528 1.5895504432403413 0.8686377601432592 0.4373734471212647 0.045861468834661495 2263466.4834509403 573604.3258235533 7079420.200445238 0.011762348512495765 1.5833016338504111e-12 11.800436340072686 -0.7209126830970821 LTLNS(ph)PIFDKPLSR ddPTM_PC-9_AZD4547_30min_R2 2 LTLNSPIFDKPLSR 14 1 E5RGN0;A0A087WZU2;Q00536;Q00536-3;Q00536-2;E5RJM2;E5RIY8;H0YBX5;E5RIU4 E5RGN0 CDK16 Cyclin-dependent kinase 16 1 LT(0.319)LNS(0.681)PIFDKPLSR;LTLNS(0.988)PIFDKPLS(0.011)R 153.41 0.0012706 5212000.0 45045.0 74735.0 91254.0 180559.0 163770.0 155007.0 129233.0 178001.0 131258.0 160882.0 True False 59368.373005795285 98891.6272274205 90043.91233569552 138933.91215874176 141033.3623759719 145314.38778603208 140734.48664250594 150495.03550606096 138196.0299114821 155249.5701486699 0.38240603789719363 0.63698486979848 0.5799945999816153 0.8949069039334282 0.9084299701500989 0.9360050893981625 0.9065048393224918 0.9693748933536117 0.8901540260571605 1.0 17.244229748388264 -5.421633898978322 0.9656010841996667 0.9460399849530291 0.37609442642667595 0.894092428489695 0.06307757065945123 0.25771179141984896 0.36085027038203304 0.022204383992833032 0.12456125482445526 3.7876173827695016e-06 5.421633898978322 -0.5699455585263531 down LTLNS(ph)PIFDKPLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTLNSPIFDKPLSR 14 1 E5RGN0;A0A087WZU2;Q00536;Q00536-3;Q00536-2;E5RJM2;E5RIY8;H0YBX5;E5RIU4 E5RGN0 CDK16 Cyclin-dependent kinase 16 1 LTLNS(0.998)PIFDKPLS(0.002)R 124.5 0.00018305 4538700.0 13913.0 16290.0 22816.0 27137.0 33833.0 29574.0 30093.0 28675.0 23873.0 23808.0 True False 16268.196105724204 17907.16354314053 23360.019970161862 25616.60186934106 27203.666522222666 28023.087377948472 27242.37318554712 27922.311633673904 24222.097461721194 28124.20193597569 0.5784411640464857 0.6367172154397807 0.8306020566677976 0.9108383565036567 0.9672689231911857 0.9964047136961467 0.9686451991620584 0.9928214744453413 0.8612545705959026 1.0 14.779524537946829 -5.3498079734121635 1.442108894096784 0.9655374571607271 0.5517302874641176 0.9308013946301719 0.03809272921412816 0.12058471239382915 0.422722200171992 0.011540846720652875 0.05268327297367766 4.4688114034803594e-06 5.3498079734121635 -0.4138071696966096 LTLNS(ph)PIFDKPLSR ddPTM_PC-9_Lapatinib_30min_R1 2 LTLNSPIFDKPLSR 14 1 E5RGN0;A0A087WZU2;Q00536;Q00536-3;Q00536-2;E5RJM2;E5RIY8;H0YBX5;E5RIU4 E5RGN0 CDK16 Cyclin-dependent kinase 16 1 LT(0.086)LNS(0.914)PIFDKPLSR;LT(0.005)LNS(0.994)PIFDKPLS(0.001)R 80.541 0.0054145 37800000.0 191164.0 156960.0 191971.0 153427.0 156597.0 174104.0 138841.0 145820.0 168561.0 146580.0 True False 188437.9663048158 156596.56876359362 176187.88540948965 164710.53339746795 147386.2723415475 166657.97777624681 146029.50762576947 152595.3295420817 149575.88515397956 171916.1576944273 1.096103873143531 0.9108891849591967 1.0248477384112733 0.9580864044799849 0.8573148348482724 0.9694142773506685 0.8494228208923207 0.8876148210182346 0.8700513503788486 1.0 17.39134561861377 -1.5228787452811663 0.5041773612884011 0.9005260364570958 6.343875687405264 0.40487686585511196 0.05967045343029472 107.17318566571089 1.1257254934234153 0.03146328650654441 619.157078899303 0.029999999999942753 1.5228787452811663 5.443349650948168 LTLPHSIR ddPTM_PC-9_Lapatinib_30min_R1 1 LTLPHSIR 8 0 O76021;J3QSV6;I3L3C4;I3L3U9;I3L234 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 0 136.27 2.0373999999999998e-08 0.0 19865.0 17526.0 18275.0 17230.0 18072.0 16642.0 18396.0 16229.0 20161.0 16321.0 False True 19581.721457205167 17485.419623794238 16772.500043540036 18497.151677595048 17009.040490919037 15930.260454396794 19348.4548676807 16983.058586877312 17890.255875258117 19142.06310363451 1.022968180137656 0.9134553328514665 0.8762117203738313 0.9663091996642194 0.8885688234770015 0.8322123048153628 1.010782106553969 0.8872115035318597 0.9346043724963631 1.0 14.224458709320043 -10.716601669605437 4.909281427079465 1.0000085104274226 0.9226976947932453 0.1294777115047301 0.057196843144038445 5.162139129834128e-06 8.478427602409576e-07 0.05365924920942926 0.013012847131990489 1.9204293310141453e-11 10.716601669605437 -0.0773108156341773 LTNENLDLK ddPTM_PC-9_AZD4547_30min_R2 1 LTNENLDLK 9 0 A0A0A0MR36;Q9ULV0-2;Q9ULV0 A0A0A0MR36 MYO5B Unconventional myosin-Vb 0 99.139 0.019522 4788400.0 21412.0 19685.0 22760.0 33327.0 28640.0 22362.0 19999.0 26962.0 22679.0 20505.0 False True 28220.570602732576 26047.791288844226 22458.187528880168 25643.97504701723 24663.830362385273 20963.700604948455 21778.872256803414 22795.64242512358 23877.765639903857 19787.126191236257 1.4262086535452279 1.316400928416822 1.134989857133823 1.2959928995841234 1.2464584358545667 1.0594616116732154 1.100658683141633 1.1520441222646975 1.2067323677593642 1.0 14.272274475476344 -1.5228787452803376 0.28885875761039637 1.086682589052258 3.6457589082336908 0.6348727902504432 0.07447605301436007 37.4360005469769 0.5308848516238571 0.0832295170719193 48.866565299023335 0.029999999999999995 1.5228787452803376 2.5590763191814325 LTNENLDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTNENLDLK 9 0 A0A0A0MR36;Q9ULV0-2;Q9ULV0 A0A0A0MR36 MYO5B Unconventional myosin-Vb 0 111.74 0.0024631999999999996 0.0 17112.0 15138.0 15832.0 16280.0 16652.0 17815.0 12163.0 11629.0 12982.0 17800.0 False True 20008.723622594167 16640.800596443296 16209.494923194348 15367.884380472131 13389.16013738219 16880.750038484886 11010.832587505718 11323.75107194399 13171.837190468921 21026.999095277522 0.9515729530367435 0.7914015937814289 0.7708896000682692 0.7308643668474605 0.6367603896644137 0.8028130862608993 0.523652116862394 0.5385338640399335 0.6264249658633979 1.0 14.35995534757992 -4.222920414852684 0.6485414689714835 0.6588634063868656 1.3714414555707424 0.2434264682619629 0.13216216814313506 7.84379238243235 1.4818974119780002 0.05690456273449843 4.872123197940273 5.985212649752001e-05 4.222920414852684 0.7125780491838768 LTNENLDLK ddPTM_PC-9_Lapatinib_30min_R1 2 LTNENLDLK 9 0 A0A0A0MR36;Q9ULV0-2;Q9ULV0 A0A0A0MR36 MYO5B Unconventional myosin-Vb 0 ; 115.49 0.0091017 6734000.0 25744.0 44449.0 39672.0 39887.0 36566.0 39150.0 34450.0 35132.0 39840.0 35311.0 False True 25376.885839128594 44346.0810714384 36410.32129834858 42820.42303913139 34415.25977152198 37475.64576310747 36233.65243485543 36764.36097567156 35352.79966620124 41414.45930105005 0.6127542473670584 1.0707873969590622 0.8791693025296943 1.033948619921876 0.8309962354295278 0.9048927933765706 0.8749034285698556 0.8877179998517912 0.8536342200972519 1.0 15.33784693277981 LTPAEEENNS(ph)FQRLSP ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTPAEEENNSFQRLSP 16 1 Q5HYI7-5;Q5HYI7 Q5HYI7-5 MTX3 Metaxin-3 1 LTPAEEENNS(0.789)FQRLS(0.211)P 102.15 0.0074346 12237000.0 24711.0 20905.0 21342.0 22579.0 28832.0 21648.0 24275.0 25082.0 24571.0 17819.0 True False 28894.084235502825 22980.310243668086 21850.874219985708 21313.971832105668 23182.576572243768 20512.740770874003 21975.49626421946 24423.624076575714 24930.304391234935 21049.4436448736 1.3726768613449656 1.0917300538375383 1.038073717701669 1.0125669918737492 1.1013391595216662 0.9745027525166772 1.043994161317009 1.160297843906381 1.184368803842779 1.0 14.36149448165874 -4.762487482521807 4.562323752701081 1.0655253485781717 1.397411081547243 0.6733417885410198 0.06402795631652061 0.12521428938337165 5.875862066468905 0.016996618485181067 0.1364181414543809 1.7278757815912866e-05 4.762487482521807 0.3318857329690712 LTPAEEENNSFQRLS(ph)P ddPTM_PC-9_AZD4547_30min_R2 1 LTPAEEENNSFQRLSP 16 1 Q5HYI7-5;Q5HYI7 Q5HYI7-5 MTX3 Metaxin-3 1 LTPAEEENNS(0.016)FQRLS(0.984)P 112.34 0.0017279 17528000.0 27004.0 20468.0 31476.0 46825.0 36587.0 31918.0 28180.0 40347.0 30197.0 35442.0 True False 35590.71028190686 27083.880726444662 31058.607673946957 36030.21968903837 31507.526587590462 29922.16241430753 30687.965408106415 34112.29823182483 31793.15177160268 34201.18636770523 1.040627944869003 0.7918988667603313 0.9081149215126151 1.053478651344686 0.9212407502139084 0.8748866806141495 0.8972778042893796 0.9974010218556532 0.9295920740814898 1.0 15.061758749605632 -8.536036569909891 1.0197602844813964 0.9965163404500409 0.9264739348909715 0.060506592417030935 0.07467376327859929 1.7165105257025055 3.919115555253963 0.07174763946356157 0.02369086553536478 2.9104720304919685e-09 8.536036569909891 -0.07004240555906938 LTPAEEENNSFQRLS(ph)P ddPTM_PC-9_Lapatinib_30min_R1 1 LTPAEEENNSFQRLSP 16 1 Q5HYI7-5;Q5HYI7 Q5HYI7-5 MTX3 Metaxin-3 1 LTPAEEENNS(0.478)FQRLS(0.522)P 80.488 0.038729 11916000.0 50922.0 27750.0 42467.0 33572.0 46581.0 44730.0 30711.0 31913.0 40009.0 27260.0 True False 50195.842942048854 27685.746579954903 38975.52718736057 36040.99687290894 43841.197161769545 42817.002170722764 32301.065309922902 33395.79448413431 35502.765106552346 31971.854678333224 1.570000972638779 0.8659412116844463 1.219057435969569 1.1272726351197042 1.3712434765781658 1.3392092076453452 1.010296888776139 1.0445372913184816 1.110438085739579 1.0 14.964514816430565 -7.276485539493714 24.59778589451494 1.045029492258507 1.2300768012518815 0.25329482160426586 0.1726799809072025 1079.8830434836948 1765408.465474451 0.07093274465206248 0.048033861839403155 5.290716131737222e-08 7.276485539493714 0.1850473089933744 LTPEEEEILNK ddPTM_PC-9_AZD4547_30min_R2 1 LTPEEEEILNK 11 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 0 109.44 0.0094946 2783000.0 9035.1 9261.4 6807.2 14786.0 13886.0 8649.7 7159.9 14590.0 9671.6 12554.0 False True 11908.073858245327 12254.966433451962 6716.932080254533 11377.316141422778 11958.16858980733 8108.832891629671 7797.117229435802 12335.450744846556 10182.821031037274 12114.488281140208 0.9829613584903767 1.0115958799952327 0.5544544618291 0.9391495437025552 0.987096467658792 0.6693500132608551 0.6436191978141022 1.0182395210246182 0.8405490017180383 1.0 13.564445845844846 -8.534149858748082 1.389352193284358 0.9901385856612082 0.8368095729757083 0.06759389692149975 0.16210840393485995 1.350587135373936 5.739218410371343 0.15841760528255186 0.04756677539145317 2.923143536523437e-09 8.534149858748082 -0.1533290126854998 LTPEEEEILNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTPEEEEILNK 11 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 0 99.01299999999999 0.021830000000000002 2645500.0 17864.0 12559.0 18294.0 22874.0 20114.0 20555.0 18232.0 18926.0 20025.0 15224.0 False True 20888.02236991713 13805.774520460534 18730.198340381343 21592.443938508583 16172.806089557129 19477.05961499055 16504.932971750735 18429.21255375458 20317.827741421974 17983.99068688231 1.161478713684669 0.7676702440983021 1.0414928847824263 1.2006480827560877 0.8992890605394789 1.0830221141738747 0.9177569794778412 1.0247565668056657 1.1297730350940398 1.0 14.13442557311282 LTPEEEEILNK ddPTM_PC-9_Lapatinib_30min_R1 4 LTPEEEEILNK 11 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 0 ;;; 185.61 0.0018736 34601900.0 98637.0 91367.0 100213.0 98403.0 104156.0 88603.0 103406.0 82320.0 82810.0 94937.0 False True 97230.41829218958 91155.44532507156 91973.87397336682 105639.88488278483 98029.74885857466 84813.65623368089 108759.85671055602 86144.88772393513 73483.06577204126 111346.73395439905 0.8732220051645999 0.8186629467048703 0.8260132175141643 0.9487470456569349 0.8804007569608802 0.7617076246566467 0.9767673720461126 0.7736633546810175 0.6599481023137644 1.0 16.76469971575159 LTPEELER ddPTM_PC-9_AZD4547_30min_R2 2 LTPEELER 8 0 Q5H8X8;O95399;O95399-2 Q5H8X8 UTS2 Urotensin-2 0 ; 153.04 0.00051874 23843000.0 44844.0 42963.0 65864.0 80482.0 64256.0 48440.0 47386.0 65860.0 55852.0 49906.0 False True 59103.459186855005 56849.94956274393 64990.600325226886 61928.11833450475 55335.163539295696 45411.03914246057 51603.26220115438 55682.850312240924 58804.22269588211 48158.80613020415 1.2272617188030042 1.180468415455359 1.349506051904933 1.2859147331657954 1.149014437560791 0.942943623222 1.0715228708460431 1.1562340262691406 1.2210481824839379 1.0 15.555512007291105 -6.434820085715654 4.749946957157524 1.0837330957624414 1.2596420386420886 0.520582790658018 0.08224346304910131 0.20345155363362707 7.846116355787618 0.028066706615362782 0.03158453178585188 3.6743448530393873e-07 6.434820085715654 0.1759089428796472 LTPEELER ddPTM_PC-9_Lapatinib_30min_R1 4 LTPEELER 8 0 Q5H8X8;O95399;O95399-2 Q5H8X8 UTS2 Urotensin-2 0 ;;; 139.97 0.011986 32364400.0 60650.0 65330.6 70902.3 56664.5 58457.0 67688.0 64385.0 50321.6 65390.0 48796.0 False True 59785.11987815217 65179.3310096001 65072.98658479287 60831.79635723068 55018.67419088395 64793.14202843465 67718.54026177558 52659.725244032605 58025.08961277354 57230.32358341703 1.0446406054477633 1.1388950285174757 1.1370368453350546 1.0629294497796133 0.9613552876507949 1.132147050225818 1.1832632776061676 0.9201367727246471 1.013887148972661 1.0 15.804492143537 -7.772212728348092 24.999810051354032 0.9752589751484891 1.0928140937326987 0.4183692882675498 0.06280540198452064 226.53498661714548 525671.3711722889 0.03558370863311855 0.017362725280922368 1.6896131139652043e-08 7.772212728348092 0.11755511858420953 LTPLSHEVISR ddPTM_PC-9_AZD4547_30min_R2 1 LTPLSHEVISR 11 0 Q2VIR3;P41091;Q2VIR3-2;H7BZU1 Q2VIR3 EIF2S3L;EIF2S3 Putative eukaryotic translation initiation factor 2 subunit 3-like protein;Eukaryotic translation initiation factor 2 subunit 3 0 160.91 0.0010535 4555900.0 18412.0 26753.0 37543.0 53064.0 48418.0 32457.0 32739.0 36693.0 33723.0 43612.0 False True 24266.633006609 35400.384066570965 37045.155289839575 40830.91463062751 41695.996455515735 30427.458659100805 35652.707576153145 31022.93997125802 35505.52893313099 42085.15715445969 0.5766078743046231 0.8411607906475324 0.8802427695322024 0.9701975088454845 0.9907530178035057 0.7229973871174308 0.8471563369788936 0.7371468248864689 0.8436591742504289 1.0 15.361023884210104 -4.761328012309034 4.4802265109194925 0.8656744415040802 0.5519098007152734 0.48608861804803694 0.09084753946528466 0.19410098290381608 8.528747424875817 0.02386652670417844 0.19760391759504026 1.7324949911601295e-05 4.761328012309034 -0.31376464078880684 LTPLSHEVISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTPLSHEVISR 11 0 Q2VIR3;P41091;Q2VIR3-2;H7BZU1 Q2VIR3 EIF2S3L;EIF2S3 Putative eukaryotic translation initiation factor 2 subunit 3-like protein;Eukaryotic translation initiation factor 2 subunit 3 0 71.153 0.025547 4936600.0 37501.0 46416.0 46990.0 47096.0 57919.0 50531.0 47665.0 53845.0 40190.0 38336.0 False True 43849.178621488056 51023.873727342616 48110.419810567386 44457.36380729209 46570.18772502037 47881.06540525847 43149.82613528407 52431.625803493356 40777.702717989974 45286.013332390976 0.9682719982358169 1.1267027051561551 1.0623681854581852 0.9817018663352688 1.0283569759873494 1.0573036105832565 0.9528289853772801 1.157788507870077 0.900448057078665 1.0 15.466777919627583 -8.295061340452058 24.998633758798693 0.9502240463035031 1.0405077387565984 0.23635122241187978 0.0658870114991417 1029.5365571678894 765473.0686791181 0.05942729618241028 0.015347033288724577 5.069191051473453e-09 8.295061340452058 0.09028369245309531 LTPS(ph)PDIIVLSDNEASSPR ddPTM_PC-9_AZD4547_30min_R2 2 LTPSPDIIVLSDNEASSPR 19 0 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 LTPS(1)PDIIVLSDNEASSPR;LTPS(1)PDIIVLSDNEASSPR 195.45 9.3205e-15 12825800.0 20202.6 19374.9 28802.9 41825.0 33763.0 27217.5 19151.4 26876.4 20661.4 26222.8 True False 26626.60655981529 25637.457528180243 28420.954726519452 32182.892439808424 29075.59024180217 25515.58542237656 20855.837498822184 22723.269938231246 21753.5194229159 25304.747753599124 1.0522375808321645 1.0131481166230474 1.1231471265101667 1.2718124184909534 1.149017193331505 1.0083319411373088 0.824186737678736 0.8979844477998912 0.8596615795082119 1.0 14.627120472688993 -6.995985660049447 3.920792171208063 0.8881440998072521 1.1229611032349769 0.662037879265266 0.07607753641515858 0.141701554572632 4.933622777950401 0.03173413173572501 0.026161329743448175 1.009286211103879e-07 6.995985660049447 0.23481700342772482 LTPS(ph)PDIIVLSDNEASSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LTPSPDIIVLSDNEASSPR 19 0 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 LT(0.001)PS(0.999)PDIIVLSDNEASSPR;LTPS(1)PDIIVLSDNEASSPR 235.02 1.6144e-43 9279200.0 23133.0 25400.0 30873.0 29756.0 32111.0 25986.0 27499.0 26417.0 26135.0 16925.7 True False 27048.96000242347 27921.544137247987 31609.129406504504 28088.86779025363 25819.080060742246 24623.248414261456 24894.095644480785 25723.581741125152 26517.174932437632 19994.19542623253 1.35284063328375 1.3964825061484953 1.5809152972983898 1.4048511176099054 1.2913287836962635 1.2315198431018421 1.245066136135668 1.2865524814954856 1.3262436605799555 1.0 14.287293607287207 -6.309471240211238 2.917333007321815 1.239386507773168 1.445302445366581 0.5120117252548424 0.09862324129769932 0.23420952881165188 3.9682213088740066 0.0315764450260975 0.03818539959715132 4.903754952945178e-07 6.309471240211238 0.20591593759341298 LTPS(ph)PDIIVLSDNEASSPR ddPTM_PC-9_Lapatinib_30min_R1 3 LTPSPDIIVLSDNEASSPR 19 0 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 LTPS(1)PDIIVLSDNEASSPR;LTPS(1)PDIIVLSDNEASSPR;LT(0.036)PS(0.963)PDIIVLSDNEASSPR 292.45 4.710899999999998e-121 9897700.0 38338.9 28194.3 39669.8 29826.7 31855.4 29284.0 27710.0 29806.6 37176.7 21726.2 True False 37792.18025550683 28129.017830602625 36408.30217385631 32020.255016954405 29981.72800212607 28031.591584338137 29144.688213928704 31191.523450343022 32989.468557993554 25481.544721658225 1.4831196722302744 1.1038976693863525 1.428810638112956 1.2566057264863757 1.1766055916006881 1.1000742651410957 1.1437567279489522 1.2240829114190852 1.2946416286118603 1.0 14.637165117690188 -6.134491000251309 3.599304119232188 1.1641223493855706 1.3182882645053242 0.32130143884907425 0.1175820079449354 0.331971204885862 7.785988898361139 0.03450815187311256 0.046079346387333624 7.336839181631505e-07 6.134491000251309 0.15416591511975364 LTPSPDIIVLS(ph)DNEASSPR ddPTM_PC-9_AZD4547_30min_R2 2 LTPSPDIIVLSDNEASSPR 19 0 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 LTPSPDIIVLS(1)DNEASSPR;LTPSPDIIVLS(0.998)DNEAS(0.002)SPR 216.16 9.1264e-28 7462900.0 38939.0 35046.0 51041.0 69960.0 51945.0 48057.0 44989.0 60390.0 42994.0 48687.0 True False 51320.7920184851 46373.93413811707 50364.16299040302 53831.802871225365 44733.33338596733 45051.98819300635 48992.93384475864 51058.11312414557 45266.57506600937 46982.48294916946 1.0923388632739839 0.9870473254529611 1.0719774654075267 1.1457845454755171 0.9521279118935563 0.9589103292337333 1.0427914994991707 1.086747866846151 0.9634777096600761 1.0 15.51983533904253 -6.2760627036102985 24.991509450055652 1.005030786401239 1.0678906778086312 0.31250751835198 0.05291394332681895 1225.3999581282453 2094226.0331742947 0.01742356758490095 0.01985044711958133 5.29586976392974e-07 6.2760627036102985 0.06285989140739212 LTPSPDIIVLS(ph)DNEASSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LTPSPDIIVLSDNEASSPR 19 0 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 LTPSPDIIVLS(1)DNEASSPR;LTPSPDIIVLS(0.999)DNEASS(0.001)PR;LTPSPDIIVLS(0.998)DNEAS(0.001)S(0.001)PR 180.76 3.9353e-09 11943500.0 41998.5 47721.0 50956.0 57849.0 63132.0 62263.0 57391.0 49741.0 56525.0 42795.9 True False 49108.016541813966 52458.42550289804 52170.98429170611 54607.90807898847 50761.73779685401 58997.81867225283 51954.509005141874 48435.3514549459 57351.5711902061 50554.457897841996 0.9713884508671633 1.037661715390233 1.0319759416099508 1.0801798763095727 1.0041001309801576 1.1670151580197492 1.0276939198938506 0.9580826987171283 1.1344513139889538 1.0 15.625550694299715 -4.1903878736485725 1.337141180197638 1.0523650018633564 0.7450259448228838 0.13564206227656672 0.05966140140579486 11.336350618281555 5.9123833437602045 0.016755283307281314 6.985937379201822 6.450778448685911e-05 4.1903878736485725 -0.3073390570404726 LTPSPDIIVLS(ph)DNEASSPR ddPTM_PC-9_Lapatinib_30min_R1 3 LTPSPDIIVLSDNEASSPR 19 0 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 LTPSPDIIVLS(0.999)DNEAS(0.001)S(0.001)PR;LTPS(0.004)PDIIVLS(0.857)DNEAS(0.055)S(0.084)PR;LTPSPDIIVLS(0.917)DNEAS(0.041)S(0.041)PR 111.63 0.00012313 15258200.0 46654.7 40522.1 50493.1 37218.4 42344.8 45300.5 40903.5 46284.1 43070.3 37021.9 True False 45989.39542257584 40428.27356712039 46341.7522270025 39955.565292942745 39854.162117079955 43363.103215623196 43021.2830876374 48434.62825441418 38219.269263634225 43421.08608641912 1.0591488967144933 0.9310746738729136 1.067263774442917 0.9201880674615301 0.9178527233924995 0.9986646379438662 0.990792422879842 1.1154633064225252 0.8802006745655339 1.0 15.406108191911867 -6.976735769949701 24.967461885015965 1.004592157880649 0.9760814206337346 0.009681266378283704 0.07192486071920076 964.3423374114195 1034941.7546666126 0.02453926269631273 0.021640868011876428 1.0550285934044632e-07 6.976735769949701 -0.02851073724691433 LTPSPDIIVLSDNEAS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 2 LTPSPDIIVLSDNEASSPR 19 0 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 LTPSPDIIVLS(0.288)DNEAS(0.356)S(0.356)PR;LTPSPDIIVLSDNEAS(0.956)S(0.044)PR 171.3 3.5346000000000004e-08 18001100.0 52028.0 51065.0 61352.0 86427.0 73747.0 66231.0 55373.0 69361.0 56633.0 62015.0 True False 68571.82175037234 67570.76261949865 60538.432393315365 66502.59043383926 63508.502015880906 62089.56510000627 60301.089728285144 58642.85120721745 59626.50476143904 59843.873725896905 1.1458453051427133 1.1291174586891424 1.0116061782798311 1.1112681431426263 1.0612364818956925 1.0375258357170412 1.0076401471683205 0.9799307356976839 0.9963677323855491 1.0 15.868915944217857 -4.075429736354044 0.28202177845025184 0.9788143069336129 1.3556407636537686 0.7113059136382283 0.030864857252873187 7.127477990077455 0.3428806180936414 0.03825114577116275 0.9943383579558523 8.405629891243655e-05 4.075429736354044 0.3768264567201557 LTPSPDIIVLSDNEAS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LTPSPDIIVLSDNEASSPR 19 0 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 LTPSPDIIVLS(0.049)DNEAS(0.692)S(0.26)PR;LTPSPDIIVLS(0.086)DNEAS(0.747)S(0.168)PR 221.99 1.164e-28 6068000.0 31905.5 28806.0 27656.2 38001.4 36512.8 34401.6 37215.6 31693.9 30317.0 25777.5 True False 37306.47098765063 31665.669307778164 28315.628694722578 35872.30476020108 29358.37894932792 32597.51953544435 33690.268950388694 30861.96870746285 30760.328770870907 30450.756695422275 1.2251410157324265 1.039897616486441 0.9298825962830449 1.178043131046193 0.9641264170535843 1.0704994907514007 1.1063852792680657 1.0135041639901972 1.0101663179849705 1.0 14.894190458819613 -4.761856495293404 8.471341111839397 1.0373845421929282 1.2269119591856081 0.41843357049943075 0.0672868394517439 0.0837440097553929 65.74320991709675 0.01599215642098258 0.09170584203696826 1.7303880399907525e-05 4.761856495293404 0.18952741699267994 LTPSPDIIVLSDNEAS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 3 LTPSPDIIVLSDNEASSPR 19 0 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 LTPSPDIIVLS(0.144)DNEAS(0.816)S(0.04)PR;LTPSPDIIVLS(0.095)DNEAS(0.589)S(0.316)PR;LTPSPDIIVLS(0.334)DNEAS(0.539)S(0.127)PR 234.62 1.6989999999999997e-43 13220600.0 57635.7 48412.5 59336.2 46812.3 58434.2 57816.3 49082.7 46526.9 55665.5 42161.5 True False 56813.80434890706 48300.40383070515 54457.80668035568 50255.03270325499 54997.21524205743 55343.63162537804 51623.962042504434 48688.70962879919 49395.86520629833 49449.059098332604 1.148936003735262 0.9767709378384071 1.1012910593923104 1.016299068569124 1.1121994279545737 1.1192049481735074 1.043982696209586 0.9846235806424262 0.9989242688737819 1.0 15.59365544963224 -7.597419289669399 4.434470253354225 0.9946847202148511 1.0747139459520068 0.3830433809414109 0.04777412569517668 0.23195938049581982 8.70805464558455 0.022913603256415623 0.01281708095044604 2.52685726372775e-08 7.597419289669399 0.08002922573715565 LTPSPDIIVLSDNEASS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTPSPDIIVLSDNEASSPR 19 0 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 LTPSPDIIVLS(0.009)DNEAS(0.172)S(0.819)PR 108.71 0.00017830000000000002 3029300.0 2869.5 3443.4 5558.3 4516.6 5978.6 5339.4 5602.9 4670.3 3729.8 3556.3 True False 3355.249674791603 3785.2379953621926 5690.830951970139 4263.54954501477 4807.136247739203 5059.392464523497 5072.152750516797 4547.709573591884 3784.3412689116476 4201.029038344689 0.7986732879412934 0.9010263820632078 1.3546278542774532 1.014882188649359 1.144275891421435 1.2043221835279256 1.2073596026642446 1.0825227657516492 0.9008129280636378 1.0 12.036527042714818 -5.028367391081207 16.12339649468597 1.1211841260144007 0.8242491292701216 0.44141605763609637 0.1208574940694338 6.495488497416113 3694.209823928253 0.030258181835305972 0.08154886448772307 9.367692124501798e-06 5.028367391081207 -0.29693499674427903 LTPVRPAAAS(ph)PIVSGAR ddPTM_PC-9_AZD4547_30min_R2 2 LTPVRPAAASPIVSGAR 17 1 I3VM54;Q9Y2K7;Q9Y2K7-3;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 1 LTPVRPAAAS(0.755)PIVS(0.245)GAR;LT(0.002)PVRPAAAS(0.632)PIVS(0.366)GAR 90.853 0.0010925000000000002 77688000.0 94116.0 78106.0 98880.0 112178.0 95440.0 92705.0 86963.0 127521.0 92796.0 77679.0 True False 124042.93026558837 103352.2370539227 97568.78659295569 86317.09523282314 82189.80341431758 86908.14169491758 94702.53853034612 107815.55959106062 97701.0071132113 74959.48185364754 1.6547997291092857 1.3787746993196908 1.3016203444875865 1.1515167007337437 1.0964563972678822 1.1594015799708814 1.263383046260183 1.4383178341808975 1.303384237686765 1.0 16.193823360164522 -4.733331624354305 1.5171487157875592 1.2193005130044219 1.8566615361271213 0.5862814487655887 0.11496233231512504 0.9900707753951087 1.9660890183230824 0.03518417055704646 0.9864934532314641 1.847857068854226e-05 4.733331624354305 0.6373610231226994 LTPVRPAAAS(ph)PIVSGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LTPVRPAAASPIVSGAR 17 1 I3VM54;Q9Y2K7;Q9Y2K7-3;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 1 LTPVRPAAAS(0.633)PIVS(0.367)GAR;LTPVRPAAAS(0.909)PIVS(0.091)GAR;LT(0.001)PVRPAAAS(0.555)PIVS(0.445)GAR 72.66199999999999 0.0055268999999999995 54764000.0 71905.0 72612.0 72536.0 78826.0 101612.0 80958.0 79458.0 61014.0 69097.0 67753.0 True False 84077.09631151437 79820.4394840098 74265.53333431171 74409.6347773402 81701.85802784529 76712.41996158622 71931.16301389689 59412.44714967675 70107.41290631874 80036.08256754724 1.0504898992345941 0.9973056766820708 0.9279006537037164 0.9297011096781436 1.0208128060102417 0.9584729474589665 0.8987341797143791 0.7423207788753907 0.8759475808570578 1.0 16.288362934615655 -7.3336182674187 3.4407979309541097 0.8522676739759155 0.9795325157005109 0.33141753992974543 0.0689459041632867 0.2466397471219384 5.718472303089998 0.030475784259847694 0.01996258142046431 4.6385445556692533e-08 7.3336182674187 0.1272648417245954 LTPVRPAAAS(ph)PIVSGAR ddPTM_PC-9_Lapatinib_30min_R1 2 LTPVRPAAASPIVSGAR 17 1 I3VM54;Q9Y2K7;Q9Y2K7-3;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 1 LTPVRPAAAS(0.999)PIVS(0.001)GAR;LTPVRPAAAS(0.999)PIVS(0.001)GAR 129.89 9.8906e-06 24426000.0 68598.0 53213.0 56033.0 54222.0 51387.0 48355.0 44864.0 44627.0 62647.0 32634.0 True False 67619.77994066746 53089.78856789697 51426.183033634916 58209.66675928955 48364.51769072913 46286.96937101047 47186.83839876208 46700.53333887322 55591.035157844104 38274.74341792834 1.766694532797144 1.3870710506978627 1.34360621238146 1.5208375435385273 1.2636144196351327 1.209334543816409 1.2328453226588898 1.2201396839932346 1.4524208444936202 1.0 15.224105085924464 -1.5228787452803376 0.4261511427546786 1.225955715862522 10.279906745216854 0.5817370133885866 0.1283716428420234 61.38280991020356 0.7773501830457483 0.08457648627802405 475.86832147152467 0.029999999999999995 1.5228787452803376 9.053951029354332 LTPVRPAAASPIVS(ph)GAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTPVRPAAASPIVSGAR 17 1 I3VM54;Q9Y2K7;Q9Y2K7-3;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 1 LTPVRPAAAS(0.37)PIVS(0.629)GAR 68.751 0.0080229 12748000.0 19997.0 19823.0 22515.0 25858.0 25062.0 18558.0 21988.0 15669.0 17664.0 13588.0 True False 23382.097141246817 21790.896434356968 23051.842988612992 24409.26009276711 20151.281009072343 17584.785810508136 19905.137460665606 15257.705352677813 17922.30258299514 16051.396837451175 1.456701705031155 1.3575701015324955 1.436126912944321 1.52069382745652 1.2554222671795956 1.09552993976694 1.2400875551355675 0.950553120528332 1.1165571921553121 1.0 13.970411229717998 -6.555532074987022 2.8288228443456633 1.0852182358703522 1.4358807508405271 0.8138916463910052 0.08136017401070501 0.11510658186482878 1.8760826212418162 0.028506468821919897 0.029795676115702264 2.782709848150433e-07 6.555532074987022 0.350662514970175 LTPVS(ph)PES(ph)SSTEEK ddPTM_PC-9_AZD4547_30min_R2 1 LTPVSPESSSTEEK 14 0 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 2 LTPVS(0.968)PES(0.35)S(0.355)S(0.293)T(0.034)EEK 99.566 0.022507 0.0 20095.0 18118.0 17272.0 21584.0 16670.0 20446.0 19967.0 18275.0 17030.0 18756.0 True False 26484.791998034314 23974.289183199362 17042.961994675672 16608.142269475808 14355.658245145347 19167.508387835434 21744.024318795615 15451.018667722474 17930.17103256593 18099.35814888208 1.4633000673380325 1.324593335630532 0.9416335018337844 0.9176094606703842 0.7931584162851674 1.0590159181428946 1.201369912674978 0.8536777128020321 0.9906523140254784 1.0 14.143650915982585 -5.156720976004066 3.5072231890133714 0.9669753928501642 1.4381815405177658 0.7215215811817601 0.10669841696675826 0.1312735399657329 2.9356473215766474 0.029823114510522785 0.09640694810860022 6.970742240770853e-06 5.156720976004066 0.4712061476676016 LTPVS(ph)PESS(ph)STEEK ddPTM_PC-9_Lapatinib_30min_R1 2 LTPVSPESSSTEEK 14 0 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 2 LTPVS(1)PES(0.166)S(0.543)S(0.241)T(0.05)EEK;LTPVS(0.99)PES(0.276)S(0.603)S(0.083)T(0.048)EEK 137.39 6.6082e-05 0.0 34801.0 54197.0 41834.0 47099.0 51430.0 48649.0 46491.0 43659.0 45057.0 40715.0 True False 34304.73135827821 54071.51017635377 38394.570003909925 50562.817577658105 48404.98851527037 46568.39567635795 48898.0764977899 45687.556525015476 39982.20618875575 47752.53350067269 0.7183855775483611 1.1323275690826344 0.8040321044614117 1.0588509943026547 1.0136632544237363 0.9752026177983193 1.023989156451795 0.9567567032725474 0.8372792657837206 1.0 15.543289656611876 -4.737032955808219 24.975945173039968 0.9762124829197443 0.7183844126717711 0.4169818417797384 0.09207613751346738 2229.1458022127526 2281043.6011510915 0.021581024012430935 1.4494934784769473 1.8321753851185045e-05 4.737032955808219 -0.25782807024797316 LTPVS(ph)PESSSTEEK ddPTM_PC-9_AZD4547_30min_R2 12 LTPVSPESSSTEEK 14 0 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 LT(0.001)PVS(0.661)PES(0.14)S(0.14)S(0.041)T(0.016)EEK;LT(0.001)PVS(0.989)PES(0.002)S(0.004)S(0.004)TEEK;LTPVS(0.657)PES(0.264)S(0.074)S(0.004)T(0.001)EEK;LT(0.004)PVS(0.995)PESSSTEEK;LT(0.005)PVS(0.986)PES(0.002)S(0.002)S(0.003)T(0.003)EEK;LT(0.001)PVS(0.962)PES(0.018)S(0.018)STEEK;LTPVS(1)PESSSTEEK;LT(0.001)PVS(0.989)PES(0.008)S(0.002)STEEK;LT(0.002)PVS(0.408)PES(0.408)S(0.129)S(0.041)T(0.013)EEK;LT(0.009)PVS(0.991)PESSSTEEK;LTPVS(0.502)PES(0.243)S(0.243)S(0.009)T(0.003)EEK;LTPVS(0.553)PES(0.122)S(0.227)S(0.05)T(0.05)EEK 217.19 1.9957e-15 9547398600.0 926112.3 975904.0 1001128.0 1174372.0 1082092.0 1029676.0 1040360.0 1047236.0 935482.0 991692.4 True False 1220596.74706749 1291345.883157135 987852.3885945851 903638.6792665318 931862.2040675364 965290.1969457538 1132950.0245556273 885409.7392892479 984929.6686956455 956973.5509236739 1.2754759479918396 1.3494060331246605 1.0322671798411847 0.9442671413377485 0.9737596228945931 1.0086905704071472 1.1838885447378356 0.9252186107282147 1.0292130516512064 1.0 19.868119526129767 -5.283094534661584 8.191708002128008 1.0114275004285882 1.3126217960372095 0.7554338003961111 0.06834418463657996 0.09784924379319257 33.24507766061967 0.018203899787351315 0.03950586782999768 5.210812728608273e-06 5.283094534661584 0.3011942956086213 LTPVS(ph)PESSSTEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 11 LTPVSPESSSTEEK 14 0 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 LT(0.016)PVS(0.98)PES(0.003)S(0.001)STEEK;LTPVS(0.675)PES(0.108)S(0.202)S(0.005)T(0.01)EEK;LT(0.019)PVS(0.827)PES(0.075)S(0.075)S(0.004)T(0.001)EEK;LTPVS(1)PESSSTEEK;LTPVS(0.88)PES(0.046)S(0.046)S(0.014)T(0.014)EEK;LT(0.002)PVS(0.937)PES(0.021)S(0.018)S(0.018)T(0.004)EEK;LTPVS(0.814)PES(0.043)S(0.101)S(0.036)T(0.005)EEK;LTPVS(0.825)PES(0.077)S(0.077)S(0.009)T(0.011)EEK;LT(0.001)PVS(0.982)PES(0.013)S(0.004)S(0.001)TEEK;LT(0.002)PVS(0.983)PES(0.011)S(0.003)S(0.001)TEEK;LT(0.001)PVS(0.526)PES(0.177)S(0.177)S(0.06)T(0.06)EEK 225.31 2.0692e-20 4342766200.0 754032.0 909006.4 707767.5 816915.4 828701.1 729103.3 757563.2 837141.1 766162.9 603740.8 True False 881674.7247891504 999246.5479779858 724643.3614231895 771146.278613461 666323.0683356225 690867.8394349967 685801.329413394 815167.0331493125 777366.5829746973 713194.2278304563 1.2362336799488876 1.4010861403319308 1.016053317800344 1.0812570384357922 0.9342799511468057 0.9686952200056684 0.9615912505343855 1.1429804131043775 1.0899787920878916 1.0 19.44393550113209 -5.270492132799481 24.777105226743796 1.0240468392015876 1.3186599112400985 0.7309204358606265 0.07142698844579022 257.5224602610619 704832.3923180302 0.01954817296356524 0.04165635456312587 5.364235886112189e-06 5.270492132799481 0.29461307203851095 LTPVS(ph)PESSSTEEK ddPTM_PC-9_Lapatinib_30min_R1 9 LTPVSPESSSTEEK 14 0 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 LT(0.26)PVS(0.503)PES(0.098)S(0.076)S(0.023)T(0.039)EEK;LT(0.006)PVS(0.979)PES(0.003)S(0.006)S(0.006)T(0.002)EEK;LT(0.006)PVS(0.949)PES(0.036)S(0.009)STEEK;LTPVS(0.999)PESSSTEEK;LTPVS(0.995)PESS(0.004)STEEK;LT(0.003)PVS(0.633)PES(0.179)S(0.141)S(0.036)T(0.009)EEK;LTPVS(1)PESSSTEEK;LT(0.043)PVS(0.389)PES(0.197)S(0.124)S(0.124)T(0.124)EEK;LTPVS(0.997)PES(0.002)SSTEEK 233.28 9.811399999999999e-27 4588350000.0 377734.4 378346.9 417182.0 406084.69999999995 448414.2 407014.1 357759.1 396042.8 404253.1 352915.1 True False 372347.8381879945 377470.86099861417 382882.90632909053 435949.523496848 422039.35837223753 389607.0557392085 376282.11566927965 414444.3943133228 358721.8589041373 413916.0048051877 0.8995734252007058 0.9119503875581553 0.9250256136128316 1.0532318596910273 1.0196256087533342 0.941270816340092 0.9090784393475659 1.0012765621575415 0.8666537527897045 1.0 18.65897850847653 -5.540787033733071 24.999089200006352 0.970112312080764 0.9089433862508765 0.21513819292086633 0.05155811025372493 364.1823853766524 508378.6579017411 0.014453594801198188 0.025039546612349688 2.878809759103331e-06 5.540787033733071 -0.06116892582988753 LTPVSLS(ph)NSPIK ddPTM_PC-9_Lapatinib_30min_R1 1 LTPVSLSNSPIK 12 0 P46100-4;P46100;P46100-2;P46100-5;P46100-3 P46100-4 ATRX Transcriptional regulator ATRX 1 LTPVS(0.033)LS(0.646)NS(0.321)PIK 82.774 0.011746 30371000.0 20628.0 34244.0 30301.0 36915.0 38783.0 32594.0 43805.0 43587.0 37082.0 37423.0 True False 20333.840937288103 34164.71012194509 27809.768745242494 39629.852244830035 36501.86019031168 31200.03060032503 46073.00856048886 45612.21114216656 32905.43466922879 43891.51568698696 0.4632749773851332 0.7783898456729375 0.6336023787277774 0.9029046189120229 0.8316381792468793 0.7108442283658769 1.0497019262004814 1.039203372867111 0.7496992107516728 1.0 15.42165447057962 -4.171732795593318 0.39443962073534167 0.9534022414184098 2.147443779138936e-14 0.5436607258793349 0.12096327654493538 7.53217934020023 0.6403690791884263 0.09703793717970736 3.729477851501341 6.733908398989338e-05 4.171732795593318 -0.9534022414183884 LTPVSLS(ph)NSPIKGADCQEVPQDK ddPTM_PC-9_AZD4547_30min_R2 2 LTPVSLSNSPIKGADCQEVPQDK 23 1 P46100-4;P46100;P46100-2;P46100-5;P46100-3 P46100-4 ATRX Transcriptional regulator ATRX 1 LTPVS(0.026)LS(0.537)NS(0.437)PIKGADCQEVPQDK;LTPVS(0.034)LS(0.519)NS(0.447)PIKGADCQEVPQDK 97.77600000000001 3.6356999999999998e-06 40171000.0 149726.0 137060.0 149617.0 115850.0 138788.0 166720.0 162419.0 165317.0 156243.0 145557.0 True False 197335.75350573182 181361.9646456178 147632.98082198884 89142.57236465768 119519.68185526297 156294.97204440567 176873.9763527055 139771.0562567371 164501.68600359355 140461.093734103 1.4049139748213426 1.2911900357898491 1.0510595987630742 0.6346424479180491 0.8509095200519886 1.1127278585789506 1.2592382107427782 0.9950873408499 1.1711548132680791 1.0 17.099811048656335 -5.213984656754123 3.541349863903448 1.0009894904879686 1.373768804831449 0.41417466308684425 0.1635981780720303 0.2527299395114855 6.485303533247633 0.04821492392226722 0.14367987774087757 6.10963609336602e-06 5.213984656754123 0.37277931434348033 LTPVSLS(ph)NSPIKGADCQEVPQDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LTPVSLSNSPIKGADCQEVPQDK 23 1 P46100-4;P46100;P46100-2;P46100-5;P46100-3 P46100-4 ATRX Transcriptional regulator ATRX 1 LTPVS(0.03)LS(0.541)NS(0.429)PIKGADCQEVPQDK;LT(0.004)PVS(0.064)LS(0.501)NS(0.432)PIKGADCQEVPQDK;LT(0.001)PVS(0.087)LS(0.48)NS(0.431)PIKGADCQEVPQDK;LT(0.002)PVS(0.115)LS(0.441)NS(0.441)PIKGADCQEVPQDK 85.166 1.6143e-05 39846400.0 98633.0 127351.0 99531.0 122147.0 122286.0 111039.0 136069.0 108679.0 103959.0 108557.0 True False 115329.61880945145 139993.56564656176 101904.19651341962 115303.49959591715 98324.93613739607 105215.91936701206 123179.55926575004 105826.29140491899 105479.20370389464 128237.52476326084 0.8993437687007866 1.0916739535093472 0.7946519297026736 0.8991400903033556 0.7667407517332672 0.820476842182123 0.9605578358842445 0.8252365413344089 0.8225299412057406 1.0 16.96845895845557 -5.270497246923355 24.992053608803488 0.8550054949009775 0.9955088652420622 0.29841930699003405 0.08195994540620244 633.3927086694302 1747631.076886741 0.020262332301166974 0.0431607603782898 5.364172718822632e-06 5.270497246923355 0.14050337034108462 LTPVSLS(ph)NSPIKGADCQEVPQDK ddPTM_PC-9_Lapatinib_30min_R1 2 LTPVSLSNSPIKGADCQEVPQDK 23 1 P46100-4;P46100;P46100-2;P46100-5;P46100-3 P46100-4 ATRX Transcriptional regulator ATRX 1 LTPVS(0.056)LS(0.812)NS(0.133)PIKGADCQEVPQDK;LT(0.001)PVS(0.044)LS(0.536)NS(0.419)PIKGADCQEVPQDK 96.633 4.0693e-06 32804000.0 58970.0 93118.0 79760.0 77420.0 102284.0 86805.0 104622.0 105365.0 91133.0 93719.0 True False 58129.07698622648 92902.39099215278 73202.44068250373 83113.72506554889 96267.8562180811 83092.55250233819 110038.8152406224 110260.64255384349 80868.64186696582 109918.20427728216 0.5288393980635705 0.8451956762120595 0.6659719485394939 0.7561415837533546 0.8758135820271737 0.7559489626734351 1.001097279237168 1.003115391838985 0.7357165484887721 1.0 16.746070814733287 -3.4657704570830425 0.2443291321668786 0.9772620380024177 2.2443977063930402e-11 0.496512453749692 0.10670866008770115 17.381263398234214 0.5273175646977872 0.14851159815014517 5.7068712069113365 0.0003421602408215472 3.4657704570830425 -0.9772620379799738 LTPVSLS(ph)NSPIKGADCQEVPQDKDGYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTPVSLSNSPIKGADCQEVPQDKDGYK 27 2 P46100-4;P46100;P46100-2;P46100-5;P46100-3 P46100-4 ATRX Transcriptional regulator ATRX 1 LT(0.003)PVS(0.035)LS(0.536)NS(0.426)PIKGADCQEVPQDKDGYK 60.527 0.00060908 51960000.0 89614.0 56934.0 65489.0 109570.0 111460.0 124990.0 114990.0 121310.0 105220.0 91922.0 True False 104783.88024282125 62586.031256302245 67050.50612841555 103431.14813073279 89620.21312230488 118435.30436768038 104097.31474449422 118125.74103856951 106758.64344331702 108586.73094584818 0.9649786795320011 0.5763690527483849 0.6174834212649187 0.9525210606286099 0.825333006543849 1.0906977614672244 0.9586559410873801 1.087846922083679 0.9831647247632603 1.0 16.728488294262306 -6.217886630079475 1.4982214860764338 1.020259159397445 0.7166787205588359 0.48656077590284075 0.12176909589382193 0.31454084380625935 1.4108892779136673 0.043920143457328066 0.06263272572155153 6.054989159169695e-07 6.217886630079475 -0.3035804388386092 LTPVSLSNS(ph)PIK ddPTM_PC-9_AZD4547_30min_R2 2 LTPVSLSNSPIK 12 0 P46100-4;P46100;P46100-2;P46100-5;P46100-3 P46100-4 ATRX Transcriptional regulator ATRX 1 LTPVSLS(0.001)NS(0.999)PIK;LTPVSLS(0.002)NS(0.998)PIK 155.37 0.00031556 70688000.0 199833.0 230970.0 218340.0 172532.0 190201.0 236040.0 238060.0 264220.0 239840.0 211560.0 True False 263375.7372153871 305626.53563547647 215444.6689391781 132757.4129928281 163794.87425824194 221280.38148609392 259246.8788166715 223390.87017158026 252517.4527569358 204153.34879385275 1.2900877637884605 1.4970439497619408 1.0553080329665665 0.650282808375003 0.8023129438040056 1.0838929794364307 1.2698634646373121 1.094230741211857 1.2369008603033962 1.0 17.63929370719047 -5.315999662383354 7.048674861513594 1.016032260726938 1.3928111928317903 0.4008391188428988 0.18061962346664936 0.24462148117360608 27.124415378707393 0.05348872066489342 0.11329548644675336 4.830591775655108e-06 5.315999662383354 0.37677893210485225 LTPVSLSNS(ph)PIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LTPVSLSNSPIK 12 0 P46100-4;P46100;P46100-2;P46100-5;P46100-3 P46100-4 ATRX Transcriptional regulator ATRX 1 LTPVSLS(0.038)NS(0.962)PIK;LTPVS(0.001)LS(0.053)NS(0.946)PIK 134.37 5.7195e-05 71318000.0 93965.0 154179.0 125344.0 114060.0 136401.0 96217.0 139791.0 92424.0 95880.0 84048.0 True False 109871.41860665384 169484.87218648652 128332.67632976701 107669.5879875094 109674.20321277126 91171.21113965199 126548.98448080315 89997.96793132272 97282.06361286098 99285.23707639817 1.1066239235759672 1.7070500829450708 1.2925655425591356 1.0844471057128022 1.1046375719320585 0.9182756049572346 1.274600214565898 0.906458710090715 0.9798240551916516 1.0 16.599291595993513 -5.689683271070323 3.325183699353165 1.0386364727820943 1.4248517380316594 0.4561555883146845 0.1677266170490602 0.19080162259782263 4.207049291849582 0.04503821878386526 0.08179144022480174 2.043227517684183e-06 5.689683271070323 0.3862152652495652 LTPVSLSNS(ph)PIK ddPTM_PC-9_Lapatinib_30min_R1 1 LTPVSLSNSPIK 12 0 P46100-4;P46100;P46100-2;P46100-5;P46100-3 P46100-4 ATRX Transcriptional regulator ATRX 1 LTPVS(0.002)LS(0.026)NS(0.973)PIK 183.41 0.00053909 31715000.0 63025.0 117440.0 96338.0 94815.0 133660.0 117320.0 132180.0 145030.0 110310.0 126240.0 True False 62126.25194263053 117168.07489549194 88417.46151543436 101788.01139356781 125798.3815856705 112302.49708627751 139023.63363829275 151768.62325804526 97885.7261842033 148060.4157957734 0.41960068536025286 0.7913531396339403 0.5971715062410243 0.687476195757607 0.8496422282049378 0.7584910286972417 0.9389655762554017 1.0250452319908838 0.661120162726151 1.0 17.175826459638813 -4.133608531418487 0.2879044345691459 0.9536937403153588 7.762632899503703e-14 0.5300060622240464 0.12352656654666858 9.815699400601886 0.5005549015118819 0.14032512726186408 3.520727509503103 7.35176249894388e-05 4.133608531418487 -0.9536937403152812 LTPVSLSNS(ph)PIKGADCQEVPQDKDGYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTPVSLSNSPIKGADCQEVPQDKDGYK 27 2 P46100-4;P46100;P46100-2;P46100-5;P46100-3 P46100-4 ATRX Transcriptional regulator ATRX 1 LT(0.001)PVS(0.031)LS(0.262)NS(0.706)PIKGADCQEVPQDKDGY(0.001)K 50.77 0.005409399999999999 48778000.0 131770.0 102060.0 89325.0 178570.0 185180.0 188780.0 192180.0 221960.0 174720.0 121710.0 True False 154076.0584238684 112191.84230895799 91454.84676694917 168565.30183175154 148895.30832575282 178880.04447180347 173975.31913728954 216133.78518605928 177274.94946223457 143775.05954417013 1.0716466326799443 0.7803289573633649 0.6360967406788149 1.1724238012223909 1.0356129136570427 1.244166026005703 1.2100521445713008 1.503277312986675 1.233002093856012 1.0 17.13345390965359 -6.251697685677749 1.3977549172990915 1.267522160184883 0.8395048042930169 0.45597354594215556 0.17290305406128204 0.3408368451826797 1.340741147594816 0.06580212702341731 0.09274932585287077 5.601473869033865e-07 6.251697685677749 -0.42801735589186607 LTPVSPES(ph)SSTEEK ddPTM_PC-9_AZD4547_30min_R2 1 LTPVSPESSSTEEK 14 0 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 LTPVS(0.072)PES(0.449)S(0.449)S(0.022)T(0.009)EEK 143.64 6.2449e-06 0.0 15936.0 18369.0 15158.0 19401.0 17283.0 15883.0 12683.0 15923.0 15215.0 16801.0 True False 21003.31651060837 24306.420024626834 14956.995015938735 14928.399192462013 14883.55377629556 14889.833499168075 13811.762429773373 13462.46622413926 16019.233837961881 16212.802103826398 1.2954772639611358 1.4992115409149571 0.9225422551977441 0.9207784747424227 0.918012425056547 0.9183997561811916 0.8519047072383401 0.8303602386512798 0.9880607766242436 1.0 13.984845836964372 -5.269746731179588 24.95249259361618 0.9103439635598336 1.39734440674266 0.8904300149060388 0.06710131874870888 139.69573908793325 419599.8869103643 0.01663711036481597 0.03557543501237354 5.373450701571537e-06 5.269746731179588 0.4870004431828263 LTPVSPES(ph)SSTEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LTPVSPESSSTEEK 14 0 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 LT(0.012)PVS(0.051)PES(0.732)S(0.194)S(0.009)T(0.002)EEK;LT(0.011)PVS(0.155)PES(0.294)S(0.294)S(0.092)T(0.155)EEK;LTPVS(0.019)PES(0.756)S(0.21)S(0.012)T(0.003)EEK 166.64 9.63e-05 40881800.0 136123.0 258313.0 118400.0 181768.0 155398.0 131466.0 134978.0 128215.0 127918.0 114959.0 True False 159165.9353481994 283956.6075088563 121223.10503450048 171584.12825980666 124948.87743387667 124571.69152733381 122191.90668390604 124849.49210502164 129788.5587529198 135800.15668505663 1.1720600272747248 2.090988806201449 0.8926580645679019 1.2635046412924182 0.9200937648669588 0.917316257714168 0.8997920891011164 0.9193619149834162 0.9557320250662248 1.0 17.051125618589587 -5.284323359812127 24.92451022834686 0.9723372798705535 1.6315244758496585 0.5692106367993147 0.2298280402800144 425.3411357829399 463267.5202926018 0.05574696112285974 0.11616999539897593 5.196089706037175e-06 5.284323359812127 0.659187195979105 LTPVSPESS(ph)STEEK ddPTM_PC-9_AZD4547_30min_R2 3 LTPVSPESSSTEEK 14 0 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 LTPVS(0.018)PES(0.3)S(0.678)S(0.003)T(0.001)EEK;LT(0.001)PVS(0.086)PES(0.277)S(0.627)S(0.008)T(0.002)EEK;LT(0.001)PVS(0.195)PES(0.298)S(0.443)S(0.047)T(0.017)EEK 164.2 2.0377e-13 28428000.0 51114.2 117403.0 57982.0 99699.0 62242.0 61925.0 49308.0 61484.0 53974.0 76473.0 True False 67367.45235859288 155351.22380920366 57213.12079523423 76714.93588419515 53600.77267512517 58052.81996071159 53696.31647774699 51983.0605617646 56826.955449895075 73795.70354656977 0.9128912541104747 2.105152689697811 0.7752906747359501 1.0395582967209351 0.7263400184442944 0.7866693746483029 0.7276347252907645 0.7044185238908928 0.7700577773343358 1.0 16.1712492032539 -5.300031718532982 24.99160937990343 0.8062330602215696 1.509022165103047 0.48081782341187485 0.2878030087537872 348.6677851186457 225789.50777340398 0.06882865842062068 0.14328243725827264 5.011506309441536e-06 5.300031718532982 0.7027891048814775 LTPVSPESS(ph)STEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTPVSPESSSTEEK 14 0 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 LTPVS(0.17)PES(0.288)S(0.377)S(0.134)T(0.032)EEK 156.2 0.00017911 2142000000.0 70446.0 100040.0 86947.0 89802.0 91859.0 69461.0 90221.0 97557.0 73336.0 74679.0 True False 82371.11642807774 109971.3100586729 89020.1462283338 84770.68508201206 73859.8883653491 65818.34288089804 81674.61373652489 94996.23212018573 74408.40026191868 88217.71154136122 0.9337253822261953 1.2465899209719629 1.0090960723527311 0.9609259138655732 0.8372455720608849 0.7460898920511994 0.925830111771052 1.0768385447818647 0.8434632792195251 1.0 16.428780715464143 -5.704226459780649 2.8349161734235184 0.9034025159680347 1.0951374430279273 0.2892499804456673 0.11185103499674705 0.30447840655245256 4.953565987220689 0.03276817320726916 0.06081784221838554 1.9759390320246793e-06 5.704226459780649 0.1917349270598926 LTPVSPESS(ph)STEEK ddPTM_PC-9_Lapatinib_30min_R1 3 LTPVSPESSSTEEK 14 0 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 LTPVS(0.207)PES(0.144)S(0.459)S(0.144)T(0.046)EEK;LTPVS(0.097)PES(0.256)S(0.556)S(0.071)T(0.02)EEK;LT(0.001)PVS(0.097)PES(0.239)S(0.411)S(0.126)T(0.126)EEK 128.73 2.478e-05 2268635000.0 117546.0 104903.0 106580.8 110088.0 124010.0 115827.0 112603.0 100357.0 116797.0 111180.3 True False 115869.77248470335 104660.10354872099 97818.13803778548 118184.23876280221 116715.97561304062 110873.34921592458 118433.03236928959 105019.95259124093 103642.09193306488 130397.66671656223 0.8885877746306817 0.8026225175962276 0.7501525180692614 0.9063370667489961 0.8950771785413867 0.8502709596554628 0.9082450273187828 0.805382145521949 0.7948155403604392 1.0 16.99255852923156 -11.027032217912781 2.835236049598447 1.0060741415774304 0.844781164248077 0.4452415104035833 0.05203500482233541 64141688.791375 69064538.26431052 3033285.718978482 0.013452871404687108 9.39653600259889e-12 11.027032217912781 -0.16129297732935333 LTPYEVDELRR ddPTM_PC-9_Lapatinib_30min_R1 1 LTPYEVDELRR 11 1 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 103.08 0.0019312 5013200.0 21856.0 18317.0 23392.0 17283.0 22242.0 21793.0 19736.0 18090.0 18409.0 17882.0 False True 21544.32943210047 18274.58811189312 21468.800055731237 18554.04947439787 20933.769289454463 20860.964191964267 20757.83351101034 18930.527440791826 16335.584564636001 20972.879873732734 1.0272470715423037 0.8713437649915183 1.0236457837447308 0.8846686571468756 0.9981351829355941 0.9946637904549944 0.9897464552308943 0.9026193615165444 0.7788908658698481 1.0 14.356237357068098 -7.907463366376877 5.470462187133936 0.8743265614918786 0.966566280353244 0.18895836987568915 0.07072630250611091 0.2769103061219566 12.8382542784806 0.03734042257150937 0.01742783365127403 1.2374755691148975e-08 7.907463366376877 0.0922397188613654 LTQAEISEQPTMATVVPQVPTS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTQAEISEQPTMATVVPQVPTSPK 24 0 C9K0J5;Q70E73 C9K0J5 RAPH1 Ras-associated and pleckstrin homology domains-containing protein 1 1 LTQAEISEQPTMATVVPQVPT(0.297)S(0.702)PK 56.832 0.004698 4240900.0 15375.0 17437.0 15428.0 18258.0 22140.0 22477.0 23907.0 24185.0 20458.0 21117.0 True False 17977.683829907968 19168.03012288161 15795.862031015822 17235.063453234652 17801.82593331982 21298.266551502926 21642.355888308743 23550.169376125654 20757.15954726647 24945.34493791999 0.7206829119680634 0.7684010852759887 0.6332188258100281 0.6909130138759974 0.7136331839716858 0.8537972356969474 0.8675909650545542 0.9440707047640983 0.8321055330733487 1.0 14.606482998255817 -6.871668520984861 2.2379717609885112 0.9068046035082235 0.7006804537010874 0.7816147631837468 0.051965796373540714 0.1427856971140481 1.4603769613243125 0.020771605110585123 0.017830282810524782 1.343790229317087e-07 6.871668520984861 -0.206124149807136 LTQT(ph)SSTEQLNVLETETEVLNK ddPTM_PC-9_Lapatinib_30min_R1 1 LTQTSSTEQLNVLETETEVLNK 22 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 LT(0.006)QT(0.355)S(0.355)S(0.214)T(0.069)EQLNVLETETEVLNK 132.88 3.3401e-05 10311000.0 6532.8 10144.0 10011.0 10799.0 13530.0 11459.0 10564.0 9824.8 9538.3 8765.6 True False 6439.641074031203 10120.512191245505 9187.93422357752 11593.194484407948 12734.192001003466 10968.925282233678 11110.952229951024 10281.296075195767 8463.996211248175 10280.72228057218 0.6263802190435983 0.9844164558720326 0.8937051281834801 1.1276634236405734 1.2386476021308046 1.0669411139489702 1.0807559942503027 1.0000558126761845 0.8232880901026641 1.0 13.327654005364742 -4.3836252459716905 1.3726509236514128 1.0476861778721676 3.990793348708472e-16 0.5406371149916382 0.11014694649221196 2.720547266908354 2.2255538500419236 0.03378721781464003 5.158909264350582 4.134040757570998e-05 4.3836252459716905 -1.0476861778721671 LTQTS(ph)STEQLNVLETETEVLNK ddPTM_PC-9_AZD4547_30min_R2 3 LTQTSSTEQLNVLETETEVLNK 22 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 LT(0.005)QT(0.071)S(0.4)S(0.4)T(0.123)EQLNVLETETEVLNK;LT(0.002)QT(0.161)S(0.494)S(0.258)T(0.085)EQLNVLETETEVLNK;LT(0.011)QT(0.147)S(0.496)S(0.266)T(0.08)EQLNVLETETEVLNK 188.96 7.0338e-16 41303000.0 148445.0 161065.0 206132.0 200445.0 223227.0 228033.0 204111.0 261981.0 217870.0 204274.0 True False 195647.42215218712 213126.1114522579 203398.55499574367 154235.50209437907 192235.7842284981 213774.06046186457 222276.48358459916 221497.85617447845 229386.16340957952 197122.42943616613 0.9925173036462771 1.0811865096319453 1.0318387185949833 0.7824350711156638 0.975210100536781 1.0844735481057508 1.127606250695985 1.1236562820782694 1.1636735812646897 1.0 17.588732416192606 -6.8157442516536975 4.342487296550964 1.1123794146732708 0.9709408494944951 0.37401124752077264 0.08220863116192031 0.23645495112345288 9.156211809734023 0.03150353549016682 0.02833689615519006 1.5284658798158112e-07 6.8157442516536975 -0.14143856517877573 LTQTS(ph)STEQLNVLETETEVLNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LTQTSSTEQLNVLETETEVLNK 22 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 LT(0.016)QT(0.119)S(0.311)S(0.239)T(0.311)EQLNVLET(0.003)ET(0.001)EVLNK;LT(0.055)QT(0.171)S(0.538)S(0.118)T(0.118)EQLNVLETETEVLNK;LT(0.002)QT(0.117)S(0.576)S(0.117)T(0.187)EQLNVLETETEVLNK;LT(0.004)QT(0.163)S(0.456)S(0.277)T(0.1)EQLNVLETETEVLNK 126.04 2.5644e-06 50198540.0 75294.3 88512.0 92596.8 108373.0 120110.4 93583.2 103760.6 87667.3 90483.9 81974.0 True False 88040.1378597881 97298.88640457076 94804.65888731946 102301.21216000649 96575.62933972066 88675.53224819194 93931.64480630979 85366.12626618256 91807.05585877896 96835.23729417306 0.9091745971802953 1.004788020594086 0.9790305836636207 1.0564461348840246 0.9973190755585827 0.9157362002305733 0.9700151249793242 0.881560562575493 0.9480748787745609 1.0 16.563244503691664 -6.749975865531722 24.744642786315687 0.9373584995987895 0.993363344857538 0.20263483988689557 0.044838568754609835 264.6942629279029 571356.1426433224 0.014652257933180044 0.014530260296298532 1.778378234735826e-07 6.749975865531722 0.05600484525874849 LTQTS(ph)STEQLNVLETETEVLNK ddPTM_PC-9_Lapatinib_30min_R1 2 LTQTSSTEQLNVLETETEVLNK 22 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 LT(0.007)QT(0.083)S(0.387)S(0.387)T(0.137)EQLNVLETETEVLNK;LT(0.002)QT(0.161)S(0.493)S(0.259)T(0.085)EQLNVLETETEVLNK 185.67 1.2667e-15 19042300.0 44060.0 82189.0 83369.0 71907.0 85292.0 85122.0 80771.0 77934.0 85938.0 76708.0 True False 43431.6963203856 81998.6964201772 76514.72263364628 77195.28065472029 80275.29225052374 81481.53048907362 84952.92716446174 81555.0981520549 76258.75747274104 89966.87559301469 0.48275207996394814 0.9114320785253972 0.8504766018526392 0.8580411417634467 0.892276092966338 0.90568367470794 0.9442689501496677 0.9065013941463039 0.8476314973714838 1.0 16.457106300835235 -4.760234317939925 24.9999450348441 0.897068215629406 0.4827515838531062 0.8907836656732959 0.04399232854425589 8.92171472266353 185011.28342729565 0.010670389441890745 0.06413472810929412 1.7368634738030437e-05 4.760234317939925 -0.4143166317762998 LTQTSS(ph)TEQLNVLETETEVLNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTQTSSTEQLNVLETETEVLNK 22 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 LT(0.001)QT(0.061)S(0.185)S(0.568)T(0.185)EQLNVLETETEVLNK 183.65 1.6125e-15 8286400.0 41029.0 46211.0 51265.0 60487.0 63958.0 47342.0 61972.0 48140.0 48527.0 45033.0 True False 47974.3993403118 50798.5226821404 52487.35202359518 57098.1094914999 51425.889026344616 44859.302179172104 56101.56352157397 46876.37600854621 49236.61557093553 53197.126418968175 0.9018231353790919 0.9549110281270283 0.9866576553443324 1.0733307104186134 0.9667042655899548 0.8432655144917169 1.054597631453457 0.8811824841695169 0.925550285990251 1.0 15.69906069645876 -6.533268726674706 24.99669521906628 0.9366409874839571 0.983235715396997 0.06516936147693786 0.06738314063972062 546.7750974047531 1315447.9336089178 0.022219879909365872 0.02224266128713999 2.929080269019067e-07 6.533268726674706 0.04659472791303987 LTQTSS(ph)TEQLNVLETETEVLNK ddPTM_PC-9_Lapatinib_30min_R1 1 LTQTSSTEQLNVLETETEVLNK 22 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 LT(0.004)QT(0.064)S(0.188)S(0.557)T(0.188)EQLNVLETETEVLNK 163.19 6.9173e-08 6646400.0 66390.0 91894.0 104570.0 94443.0 117630.0 117540.0 99607.0 108240.0 114960.0 97188.0 True False 65443.26642556503 91681.22508895062 95972.65825187322 101388.65327261231 110711.23466947791 112513.08819912275 104764.1630792059 113269.2255495471 102011.99421753254 113986.81630513011 0.5741301366851114 0.8043142887992425 0.8419627932669426 0.889477016370087 0.9712635044838535 0.9870710652882667 0.9190901761723375 0.993704616210509 0.894945551812393 1.0 16.798507446624242 -4.241740224320903 0.7565737722278291 0.9598769404444568 7.622634780798661e-17 0.9029165207840989 0.038048482762195385 1.532453733966297 0.3757285362258823 0.014168266189682387 1.5062241597150998 5.7313875463379564e-05 4.241740224320903 -0.9598769404444567 LTQYHGGS(ph)LPNVSQLR ddPTM_PC-9_AZD4547_30min_R2 2 LTQYHGGSLPNVSQLR 16 0 Q6UUV7;Q6UUV7-3;H0YK33 Q6UUV7 CRTC3 CREB-regulated transcription coactivator 3 1 LT(0.002)QY(0.003)HGGS(0.994)LPNVS(0.001)QLR;LTQYHGGS(1)LPNVSQLR 128.4 1.1961e-05 31880000.0 70663.0 82005.0 179223.0 311100.0 286262.0 283872.0 256168.0 325250.0 205811.0 267971.0 True False 93132.36411829297 108511.51255482202 176846.38591777204 239380.70144708658 246519.4625418 266121.4389646694 278966.455736828 274990.08600146294 216689.74928851594 258589.41685402434 0.3601553584494407 0.41962859066300295 0.6838887223973407 0.9257173180533478 0.9533238658446802 1.0291273409495214 1.0788007457177051 1.0634235899789237 0.8379683589713145 1.0 17.980303706411547 -5.497638001198456 1.4755931121085422 1.0063301634395108 0.3330246008785852 0.9359665995590507 0.0629887076959577 0.1040743964020656 0.41883041068928833 0.020113613524454968 0.06856632564262446 3.179523204081404e-06 5.497638001198456 -0.6733055625609256 down LTQYHGGS(ph)LPNVSQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTQYHGGSLPNVSQLR 16 0 Q6UUV7;Q6UUV7-3;H0YK33 Q6UUV7 CRTC3 CREB-regulated transcription coactivator 3 1 LT(0.002)QY(0.001)HGGS(0.994)LPNVS(0.003)QLR 56.48 0.034796 7280300.0 22445.0 28096.0 38305.0 48760.0 63048.0 52095.0 51726.0 56331.0 48252.0 41121.0 True False 26244.495191042894 30885.185200004697 39218.33647252144 46028.13528205291 50694.19699385497 49363.0464919938 46826.13881619017 54852.37093762809 48957.594216184436 48575.911786343095 0.5402779737100358 0.635812773537849 0.8073618184465557 0.947550619008525 1.0436077292142032 1.016204218854663 0.9639785872090441 1.1292092916112713 1.007857442419612 1.0 15.567953455489558 -5.41114406623313 1.209709056858836 1.0339152779705887 0.5069819771634141 0.9473526616247744 0.041146731250167386 0.12866606320604956 0.30879508051605725 0.013542455376401495 0.06454405747269723 3.8802162825725935e-06 5.41114406623313 -0.5269333008071746 LTQYHGGS(ph)LPNVSQLR ddPTM_PC-9_Lapatinib_30min_R1 2 LTQYHGGSLPNVSQLR 16 0 Q6UUV7;Q6UUV7-3;H0YK33 Q6UUV7 CRTC3 CREB-regulated transcription coactivator 3 1 LTQYHGGS(1)LPNVSQLR;LTQYHGGS(0.999)LPNVS(0.001)QLR 104.82 0.00068054 21729000.0 145747.0 114752.0 142022.0 113802.0 137921.0 149355.0 119125.0 125872.0 140107.0 90313.0 True False 143668.62105327373 114486.29879434204 130345.49938077388 122171.37871234307 129808.75794311885 142967.4348135099 125292.70961689853 131720.4726383277 124326.67426788283 105923.48171549184 1.356343454033776 1.0808396489632937 1.230562829598814 1.1533927768773002 1.2254955732269295 1.3497237109097047 1.182860566776232 1.2435436458945524 1.1737404421979025 1.0 16.692662924004992 -8.68975134368762 3.252877131327915 1.0000196844270566 1.2228082010690067 0.43304659706274606 0.07813933979191343 0.8357558941459756 14.757239954138232 0.0726298668645871 0.019216143193201647 2.042907281184058e-09 8.68975134368762 0.2227885166419501 LTRDETNYGIPQR ddPTM_PC-9_AZD4547_30min_R2 1 LTRDETNYGIPQR 13 1 D6R9L0;P63244;D6R9Z1;D6RFX4;D6RHH4;D6RFZ9;D6RBD0;D6RAC2;D6REE5;E9PD14;D6RAU2;D6R909;D6RGK8 D6R9L0 GNB2L1 Guanine nucleotide-binding protein subunit beta-2-like 1;Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed 0 84.352 0.011187 3907000.0 31868.0 29531.0 32724.0 32260.0 31356.0 34418.0 30740.0 30684.0 35725.0 30928.0 False True 42001.3611044219 39076.31823982012 32290.058378518246 24822.955412031555 27002.760643957852 32265.83701910007 33475.800448729264 25942.49284817491 37613.350565967005 29845.220133750532 1.4073061252754697 1.309299045699803 1.0819172461724604 0.8317229794515894 0.9047599757329892 1.0811056803904147 1.12164696050853 0.8692344278887655 1.2602805540519992 1.0 14.865212274473 -5.250292091522036 3.04729348886257 1.004932432718829 1.3843799754430588 0.5675511033548417 0.12066137054982294 0.18006968286157946 3.369778072054056 0.03239928905764603 0.09703660367389055 5.619632409258073e-06 5.250292091522036 0.37944754272422987 LTRPAAS(ph)PAVGEK ddPTM_PC-9_AZD4547_30min_R2 3 LTRPAASPAVGEK 13 1 F5H0Q6;A0A0A0MQS2;Q8N2M8-3;Q8N2M8;Q8N2M8-4 F5H0Q6 CLASRP CLK4-associating serine/arginine rich protein 1 LT(0.001)RPAAS(0.999)PAVGEK;LT(0.083)RPAAS(0.917)PAVGEK;LT(0.002)RPAAS(0.998)PAVGEK 78.501 0.007043000000000001 211689000.0 255294.0 209690.0 290647.0 402117.0 354247.0 308248.0 292329.0 348081.0 268733.0 311305.0 True False 336472.1815549236 277468.1917885573 286792.83087462414 309415.138295719 305065.91879832104 288973.20383123786 318345.7146836888 294293.0795556505 282937.6777507071 300406.3067038668 1.1200569829800866 0.9236430314430071 0.9546831224064064 1.0299888231066097 1.0155110328593986 0.96194120224014 1.059717148340385 0.9796501371249752 0.9418499926155682 1.0 18.1965555754211 -4.743146638072983 24.992797876243596 0.9875764085735497 1.1200574057840864 0.5061229336987918 0.03989753655549284 1077.7706161507942 1472447.2076349556 0.010192049942519767 0.3370205082447232 1.8065640427398078e-05 4.743146638072983 0.13248099721053674 LTRPAAS(ph)PAVGEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTRPAASPAVGEK 13 1 F5H0Q6;A0A0A0MQS2;Q8N2M8-3;Q8N2M8;Q8N2M8-4 F5H0Q6 CLASRP CLK4-associating serine/arginine rich protein 1 LT(0.003)RPAAS(0.997)PAVGEK 95.073 0.017412 7485700.0 28786.0 23301.0 25210.0 27990.0 29229.0 24428.0 30660.0 30862.0 24041.0 22507.0 True False 33658.901250584124 25614.16928905572 25811.102009457394 26421.81104480436 23501.787272132136 23146.952676963727 27755.662840822588 30051.905200991947 24392.554143896432 26587.340934686024 1.265974710794508 0.9633971803340177 0.9708041910947197 0.9937741088780445 0.8839465116073923 0.8706005137492353 1.0439427887507307 1.1303087914965588 0.9174499324253123 1.0 14.698451876482887 -4.759990557060923 24.997806831689072 0.975501514256846 1.2659750655765045 0.5921668235335248 0.07246287049983836 28.124874185453464 485094.8470795635 0.019364838408072564 0.11842055972409327 1.737838614460319e-05 4.759990557060923 0.2904735513196586 LTRPAAS(ph)PAVGEK ddPTM_PC-9_Lapatinib_30min_R1 4 LTRPAASPAVGEK 13 1 F5H0Q6;A0A0A0MQS2;Q8N2M8-3;Q8N2M8;Q8N2M8-4 F5H0Q6 CLASRP CLK4-associating serine/arginine rich protein 1 LTRPAAS(1)PAVGEK;LT(0.057)RPAAS(0.943)PAVGEK;LTRPAAS(1)PAVGEK;LT(0.02)RPAAS(0.98)PAVGEK 74.618 0.009096700000000001 252898000.0 638551.0 540129.0 605242.0 554706.0 580016.0 549766.0 466467.0 491338.0 528926.0 415774.0 True False 629445.145644087 538878.3644859269 555481.3390616819 595500.9296849696 545900.5992353304 526253.7897471406 490618.37881944026 514167.3571975555 469352.78404229844 487639.9819159686 1.290798886446835 1.1050742032444498 1.1391218104782144 1.221189713249534 1.1194746523663874 1.0791850735443307 1.006107778307614 1.0543995083777977 0.962498567484523 1.0 18.895456892739375 -6.8604228760447965 1.341269966247109 1.003618781611908 1.1819388931044748 0.7170499414964898 0.051356143406732085 0.24228367178881555 0.9066446984178325 0.02525727319516159 0.020869006321683092 1.3790408274591126e-07 6.8604228760447965 0.17832011149256677 LTS(ph)DEEGEPSGK ddPTM_PC-9_AZD4547_30min_R2 1 LTSDEEGEPSGK 12 0 Q8WVC0-2;Q8WVC0 Q8WVC0-2 LEO1 RNA polymerase-associated protein LEO1 1 LT(0.073)S(0.927)DEEGEPSGK 206.74 6.7503e-08 18976000.0 48041.0 55344.0 56762.0 58822.0 56079.0 60813.0 54130.0 63334.0 54927.0 54155.0 True False 63317.038685124026 73232.86568909299 56009.298792368034 45261.49669084072 48293.398844001575 57010.35349649989 58947.4651362952 53547.18557053542 57830.32908430702 52259.04993349909 1.2115994983777258 1.4013432272933317 1.0717626681625714 0.8660987283243204 0.9241155150247871 1.0909182920287863 1.1279857787561633 1.0246490443028626 1.1066088870329163 1.0 15.673393276333512 -5.373219166643501 5.58575160732603 1.0209928168913494 1.3039647703174848 0.625001827385347 0.08729930924566198 0.1414639298975976 5.979900013684564 0.02458868167142919 0.05240930649275499 4.2342922862769175e-06 5.373219166643501 0.28297195342613546 LTS(ph)DEEGEPSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTSDEEGEPSGK 12 0 Q8WVC0-2;Q8WVC0 Q8WVC0-2 LEO1 RNA polymerase-associated protein LEO1 1 LT(0.003)S(0.997)DEEGEPSGK 142.76 8.242e-05 3313500.0 25608.0 35940.0 26591.0 32353.0 39568.0 37232.0 36315.0 28513.0 24341.0 26251.0 True False 29942.928618945258 39507.885680814645 27225.030286929086 30540.36629984122 31814.93444126462 35279.48837680994 32874.980302168064 27764.563962020715 24696.94107635219 31010.098497198345 0.9655863757301673 1.2740328988114644 0.87794078723706 0.9848522829619659 1.025953995087729 1.1376774046685894 1.0601378871833704 0.8953394315896529 0.7964160797033093 1.0 14.920450487931262 -7.7790521902382 7.599917901411069 0.883408227534963 1.0492808308693866 0.27684813725634694 0.10990018074770433 0.20138167908374763 55.09342359446643 0.05774851056653096 0.028859573818909016 1.6632127659830676e-08 7.7790521902382 0.16587260333442366 LTS(ph)DEEGEPSGK ddPTM_PC-9_Lapatinib_30min_R1 2 LTSDEEGEPSGK 12 0 Q8WVC0-2;Q8WVC0 Q8WVC0-2 LEO1 RNA polymerase-associated protein LEO1 1 LT(0.015)S(0.985)DEEGEPSGK;LT(0.001)S(0.999)DEEGEPSGK 215.02 9.3576e-11 48231000.0 143253.0 186139.0 184691.0 179376.0 199455.0 176448.0 204071.0 199546.0 173434.0 152497.0 True False 141210.18595061713 185708.00658184587 169506.41890787717 192567.90942079414 187723.44904361735 168901.7303603777 214636.79785292802 208817.63563848785 153900.03657901482 178855.90326052022 0.7895192910962038 1.0383107473469575 0.9477261628931272 1.0766651025227896 1.0495792737138832 0.9443452929499154 1.200054311544247 1.1675188340545046 0.8604694269153931 1.0 17.44843821068512 -4.17133072851941 1.4405389907370347 1.045152809488224 7.747300015422696e-15 0.33995100834947145 0.09848166566337893 6.894248572971061 3.7535573632341293 0.027784990320612643 16.02172847356219 6.740145495316553e-05 4.17133072851941 -1.0451528094882163 LTS(ph)DEEGEPSGKR ddPTM_PC-9_Lapatinib_30min_R1 2 LTSDEEGEPSGKR 13 1 Q8WVC0-2;Q8WVC0 Q8WVC0-2 LEO1 RNA polymerase-associated protein LEO1 1 LT(0.079)S(0.921)DEEGEPSGKR;LT(0.121)S(0.879)DEEGEPSGKR 78.508 0.006839499999999999 26309000.0 79877.0 55209.0 72849.0 54998.0 67176.0 59730.0 51625.0 66240.0 76520.0 53919.0 True False 78737.93933235224 55081.16695253084 66859.63642527215 59042.73638794969 63224.83975309748 57175.487137430624 54297.88989693503 69317.75222100886 67901.51180867771 63238.827307448635 1.2450885426693867 0.8710023461495001 1.057256107868987 0.933646920758053 0.9997788138245647 0.904119977738679 0.8586163312762681 1.096126464901164 1.0737313561897734 1.0 15.948522994345435 -4.747118654739197 24.995464882978258 0.9760118671870808 1.2450892325562295 0.5043513595024185 0.07968030549317714 657.9887168692744 1148391.5604198829 0.020177342888647542 0.42888068645533006 1.790116704717947e-05 4.747118654739197 0.2690773653691487 LTS(ph)PGALLFQ ddPTM_PC-9_AZD4547_30min_R2 2 LTSPGALLFQ 10 0 O60566-3;O60566;O60566-2 O60566-3 BUB1B Mitotic checkpoint serine/threonine-protein kinase BUB1 beta 1 LT(0.054)S(0.946)PGALLFQ;LT(0.042)S(0.958)PGALLFQ 197.27 0.00080878 2880400.0 16189.0 14912.6 22503.0 28602.0 19621.8 19816.6 16834.5 25067.0 17771.4 20504.0 True False 21336.765247881445 19732.806318212773 22204.595516800997 22008.250796494947 16897.651766922183 18577.464869332867 18332.737887252213 21193.471132355633 18710.75992296784 19786.161200931885 1.0783681094681736 0.9973034242379164 1.1222285763928381 1.1123052406678262 0.8540136510222276 0.9389120345617071 0.9265434412001445 1.0711259711842167 0.9456488165115428 1.0 14.272204115553343 -6.239441471697835 24.997132872222416 0.9572656494165285 1.0750105801797958 0.49210184127853096 0.06044596749598477 759.0290464743342 862516.0713141203 0.018634127086497355 0.024036937503693304 5.761804630923064e-07 6.239441471697835 0.11774493076326731 LTS(ph)PGALLFQ ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LTSPGALLFQ 10 0 O60566-3;O60566;O60566-2 O60566-3 BUB1B Mitotic checkpoint serine/threonine-protein kinase BUB1 beta 1 LT(0.054)S(0.946)PGALLFQ;LT(0.054)S(0.946)PGALLFQ 176.33 0.0016447 2918000.0 22167.0 21951.0 20825.9 24307.0 24216.0 23407.0 21397.0 19874.1 16363.6 13551.8 True False 25919.43528179317 24130.15021089491 21322.468438665564 22945.157594357268 19471.048636010528 22179.495714331497 19370.121259135063 19352.425933349565 16602.886693110253 16008.63406401023 1.6190909966556035 1.507320994059265 1.3319355263795816 1.4332988999943077 1.2162841975246543 1.3854708418998891 1.2099796385927737 1.2088742772162349 1.037120757881273 1.0 13.96656259476476 -1.5228787452805557 0.1371385359088824 0.8911257493902832 3.3423938639091073 0.8559803770149759 0.07131756985768138 27.148764911969025 0.2500686098351183 0.3208131027052764 12.986690154238097 0.029999999999984935 1.5228787452805557 2.451268114518824 LTS(ph)PGALLFQ ddPTM_PC-9_Lapatinib_30min_R1 2 LTSPGALLFQ 10 0 O60566-3;O60566;O60566-2 O60566-3 BUB1B Mitotic checkpoint serine/threonine-protein kinase BUB1 beta 1 LT(0.364)S(0.636)PGALLFQ;LT(0.05)S(0.95)PGALLFQ 163.16 0.00013702 2571100.0 19964.8 20540.1 26427.0 18288.4 18947.0 15627.599999999999 17317.1 13618.4 20043.9 12964.8 True False 19680.09829090409 20492.54066042998 24254.274071170024 19633.38994431396 17832.57471123522 14959.2439777149 18213.69470477894 14251.160580413445 17786.34491037579 15205.748405489898 1.2942538417772826 1.3476837912845732 1.5950726938513093 1.291182085929128 1.1727521879026308 0.983788734286436 1.1978163927928105 0.9372219111075252 1.1697119034242465 1.0 13.892329205080754 -6.270820364936889 2.5361138791905318 1.0646826954444373 1.407354884774676 0.6739750573813061 0.10720921321435838 0.16599427304603318 2.112055632333972 0.034344351258801885 0.04320004001573516 5.360183222555979e-07 6.270820364936889 0.3426721893302387 LTS(ph)PVTSISPIQASEK ddPTM_PC-9_Lapatinib_30min_R1 1 LTSPVTSISPIQASEK 16 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7 E9PMC9 C11orf30;EMSY Protein EMSY 1 LT(0.028)S(0.968)PVT(0.004)SISPIQASEK 88.10799999999999 0.0040788000000000005 4791700.0 17469.0 15469.0 18070.0 15233.0 20858.0 24842.0 21335.0 20213.0 27516.0 21990.0 True False 17219.888856577745 15433.18248091252 16584.35435221714 16353.285635798336 19631.17344840577 23779.565569530405 22439.62190704327 21152.169771184366 24416.85832367452 25790.942200166824 0.6676719571907056 0.5983954506637874 0.6430301856948004 0.6340708884878412 0.7611654237385244 0.9220122857464506 0.870058244979438 0.8201394740455642 0.9467222303928309 1.0 14.654576858480324 -6.510300085762222 2.5968521674135916 0.89868957657235 0.6326585587845104 0.8770203080725092 0.04855351811404532 0.09419401226323937 1.276163492204399 0.016635540696064773 0.017941654945091347 3.08816085935046e-07 6.510300085762222 -0.26603101778783966 LTS(ph)QSEAMALQSIR ddPTM_PC-9_AZD4547_30min_R2 2 LTSQSEAMALQSIR 14 0 E7EUN2;A0A087X1U1;F5GXM9;Q9UPQ3-2;Q9UPQ3;H7C0A7 E7EUN2 AGAP1 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 1 LT(0.18)S(0.811)QS(0.009)EAMALQSIR;LT(0.021)S(0.978)QS(0.001)EAMALQSIR 120.32 7.7888e-05 28252000.0 160131.0 163688.0 234030.0 300750.0 234390.0 177483.0 177094.0 214370.0 166046.0 169578.0 True False 211049.32706828698 216596.94490669685 230926.60928751458 231416.734041181 201848.99436590393 166384.959952959 192855.0229234633 181244.0422325397 174822.85257037226 163641.12583552572 1.289708354123711 1.3236094765346247 1.4111770993290338 1.4141722189920396 1.233485734929376 1.016767387192087 1.178524175623799 1.1075702474371054 1.0683307859057705 1.0 17.320175842415487 -6.534567450923641 4.309301595984931 1.0884659338741394 1.3587237624235575 0.8406253717036172 0.0584879215572965 0.08227751369108888 3.6993865423004078 0.019943718746495767 0.020871158752562628 2.920334163529688e-07 6.534567450923641 0.27025782854941816 LTSPVTSIS(ph)PIQASEK ddPTM_PC-9_AZD4547_30min_R2 2 LTSPVTSISPIQASEK 16 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7 E9PMC9 C11orf30;EMSY Protein EMSY 1 LTSPVTS(0.043)IS(0.694)PIQAS(0.263)EK;LTSPVT(0.014)S(0.115)IS(0.867)PIQAS(0.004)EK 95.073 0.0025127 16331500.0 32969.0 34040.0 47802.0 63130.0 52006.0 51434.0 44060.0 45052.0 41912.0 48810.0 True False 43452.456202199246 45042.764311519284 47168.114246728066 48576.35384877721 44785.86458890396 48217.823849160144 47981.25464447016 38090.24859196894 44127.382754956176 47101.17675660776 0.9225344077226979 0.9562980675466944 1.0014211426280537 1.0313193256251818 0.9508438572635239 1.0237074139001363 1.0186848386487273 0.8086899567031585 0.9368637005181745 1.0 15.523475483542812 -10.230715219345937 4.383616832507985 1.0000000716748831 0.9630015512783339 0.032710926786988836 0.06265365511552415 91476801.4672862 221675049.369767 126.7077059271787 0.016654416354918364 5.87874714248211e-11 10.230715219345937 -0.03699852039654927 LTSPVTSIS(ph)PIQASEK ddPTM_PC-9_Lapatinib_30min_R1 3 LTSPVTSISPIQASEK 16 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7 E9PMC9 C11orf30;EMSY Protein EMSY 1 LTSPVTS(0.003)IS(0.997)PIQASEK;LTSPVTS(0.008)IS(0.992)PIQASEK;LTSPVTSIS(1)PIQASEK 200.9 2.3097e-12 11264500.0 57216.6 55063.5 56314.0 55475.0 63253.0 57086.0 48872.0 53840.0 63578.0 52534.0 True False 56400.68079176065 54936.00384884136 51684.0802983263 59554.81655917505 59532.582900182744 54644.564853965545 51402.35302746748 56341.602952583315 56417.1761339795 61614.43190284513 0.9153810081491034 0.891609354371157 0.8388307528311353 0.9665725175082728 0.9662116660274481 0.8868793100312957 0.8342583294206094 0.9144221769572408 0.9156487269563603 1.0 15.910980691444472 -8.833385489728682 2.1843133668403913 0.9999471744409206 0.9011566185359713 0.32891712643427373 0.041872383399923205 2.170355304042438 13.605217426803632 0.043260306802713096 0.01183165241784336 1.4676230035308987e-09 8.833385489728682 -0.09879055590494934 LTSS(ph)CPDLPSQTDKK ddPTM_PC-9_AZD4547_30min_R2 2 LTSSCPDLPSQTDKK 15 1 P56962 P56962 STX17 Syntaxin-17 1 LT(0.002)S(0.186)S(0.812)CPDLPSQTDKK;LT(0.009)S(0.188)S(0.803)CPDLPSQTDKK 127.91 8.9121e-06 37437000.0 79532.0 78802.0 112093.0 174132.0 158702.0 146298.0 119752.0 141733.0 122230.0 145864.0 True False 104821.52163163314 104273.20544290089 110606.57357973496 133988.55771258168 136668.96669592403 137149.9629327768 130409.69600963643 119831.42155033168 128690.82826250936 140757.3457575465 0.7446966342501757 0.7408011630349347 0.7857961016844831 0.9519116532886033 0.9709544177632854 0.9743716194323286 0.9264858988906068 0.8513333418260133 0.914274331971124 1.0 17.102850689185985 -5.681578251692236 4.25727978549772 0.9373462740112825 0.747625573785324 0.8269520747149415 0.038822747607134986 0.09231950432844675 3.131952657584722 0.011950363098738679 0.021155390795182707 2.0817172851493864e-06 5.681578251692236 -0.18972070022595844 LTSS(ph)CPDLPSQTDKK ddPTM_PC-9_Lapatinib_30min_R1 3 LTSSCPDLPSQTDKK 15 1 P56962 P56962 STX17 Syntaxin-17 1 LT(0.017)S(0.202)S(0.781)CPDLPSQTDKK;LT(0.037)S(0.192)S(0.771)CPDLPSQTDKK;LT(0.005)S(0.17)S(0.825)CPDLPSQTDKK 109.54 0.00028403 51556000.0 133902.0 114596.0 142014.0 122111.0 132103.0 133035.0 116607.0 122766.0 123380.0 95629.0 True False 131992.5329253803 114330.6600027574 130338.15710989272 131091.4502903549 124332.96126449076 127345.4031697317 122644.33989756714 128470.15653931707 109483.64515100185 112158.34523236721 1.1768409443980388 1.0193682847753294 1.1620905857683703 1.1688069222023783 1.1085484633969986 1.1354072931969554 1.0934927725928487 1.1454355560716896 0.9761524648404541 1.0 16.775177443745804 -8.263899104798313 24.966587323200493 0.988076213045757 1.123922894378982 0.6131565216311896 0.043868828999620905 142.10614252001415 1442351.4197283282 0.035101475037572 0.01066813782559871 5.446291662781648e-09 8.263899104798313 0.13584668133322508 LTTEATQT(ph)PVSNK ddPTM_PC-9_Lapatinib_30min_R1 1 LTTEATQTPVSNK 13 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 LTTEAT(0.033)QT(0.74)PVS(0.228)NK 142.57 1.7436e-05 0.0 10827.0 30246.0 32021.0 22190.0 25465.0 23593.0 27744.0 23156.0 20234.0 19274.0 True False 10672.604994571377 30175.967245308704 29388.3569846345 23821.926623670002 23967.19876611627 22583.982387969198 29180.448567565403 24231.91229513408 17955.033846534025 22605.485219009326 0.4721245702612305 1.334895798650375 1.3000542434683662 1.0538117803212537 1.0602381914793786 0.9990487781690239 1.2908569882422645 1.071948337333501 0.7942777459797828 1.0 14.464385264494357 -8.155418302629078 7.129192139614839 0.8989630218558304 1.0939510197181075 0.07628820620391097 0.23644394046779968 0.5762001881564796 33.14123946028906 0.15703726235000676 0.05855576405889769 6.99168248530755e-09 8.155418302629078 0.19498799786227705 LTTLELLEVR ddPTM_PC-9_Lapatinib_30min_R1 2 LTTLELLEVR 10 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 ; 103.7 0.012575 5176400.0 27920.0 19215.1 32019.0 20948.6 29019.0 27388.0 23965.5 22054.5 24626.0 19331.8 False True 27521.855680099074 19170.608616522233 29386.521416914286 22489.229926481006 27312.1594735491 26216.67908454628 25206.316325907916 23079.23258391062 21852.360556723677 22673.27587199568 1.2138455790630587 0.8455156072175845 1.2960862639708053 0.9918826927986178 1.2045969725655312 1.1562810434872863 1.111719209355224 1.0179046342578288 0.9637937049808522 1.0 14.468705228627712 -7.847150266309429 3.621521835992702 0.9842490136177967 1.1140379414791295 0.18788988197321332 0.11868955424405028 0.3971601126638288 10.0173820181252 0.06792609167000152 0.030377348195936144 1.4218367451196633e-08 7.847150266309429 0.12978892786133278 LTTPTYGDLNHLVSATMS(ph)GVTTCLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTTPTYGDLNHLVSATMSGVTTCLR 25 0 P04350;M0R2D3;P68371;Q5JP53;P07437;Q5ST81;Q9BVA1;Q13885 P04350;P68371;Q5JP53 TUBB4A;TUBB4B;TUBB;TUBB2B;TUBB2A Tubulin beta-4A chain;Tubulin beta-4B chain;Tubulin beta chain;Tubulin beta-2B chain;Tubulin beta-2A chain 1 LTTPTYGDLNHLVS(0.056)AT(0.18)MS(0.511)GVT(0.169)T(0.084)CLR 53.876000000000005 0.005762399999999999 3968500.0 7412.9 8091.0 10390.0 11471.0 12215.0 12594.0 10515.0 9338.9 8580.4 8522.0 True False 8667.757558551204 8894.221008443837 10637.73700429442 10828.31705948377 9821.558436111187 11933.54846953009 9518.943077992484 9093.763770382471 8705.872117478015 10066.971139885123 0.8610094772408491 0.8835051660379878 1.0566968809663053 1.0756281019404348 0.9756219919215208 1.1854159810044183 0.9455617728234699 0.9033266951916823 0.8647955771905947 1.0 13.297342063017018 -10.513208129136672 3.9184402962420704 1.0000022066807694 0.9788365157683463 0.00308694789250763 0.10044989336144149 494213059891.3271 736694775793.5364 14442907.649806712 0.026971128306210262 3.067551557861782e-11 10.513208129136672 -0.021165690912423152 LTTTGQVT(ph)SPVK ddPTM_PC-9_AZD4547_30min_R2 3 LTTTGQVTSPVK 12 0 P49916-4;P49916-3;P49916-2;P49916;K7ENR9;K7ERZ5 P49916-4 LIG3 DNA ligase 3 1 LTTTGQVT(0.5)S(0.5)PVK;LTTTGQVT(0.5)S(0.5)PVK;LTTTGQVT(0.5)S(0.5)PVK 219.89 8.6257e-11 163100000.0 445700.0 441610.0 488510.0 439650.0 449980.0 506580.0 541990.0 551760.0 489780.0 459010.0 True False 587423.3288640913 584351.796345771 482032.03821323585 338295.4850247888 387508.04422018596 474903.47251832526 590226.0600262462 466498.1701834492 515668.7708943129 442940.19961176993 1.3261910510244015 1.3192566329674889 1.0882553415466225 0.7637497913291669 0.8748540876620153 1.0721615986414659 1.332518612091587 1.053185442622565 1.1641950117561883 1.0 18.756752411259782 -5.295695095536729 4.706517825006099 1.0388506728338607 1.326126071439505 0.3772622054595035 0.14428012400292958 0.21597421727257096 12.030237890600402 0.04289469731298712 0.09956387164588557 5.061799102403253e-06 5.295695095536729 0.2872753986056442 LTTTGQVT(ph)SPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 LTTTGQVTSPVK 12 0 P49916-4;P49916-3;P49916-2;P49916;K7ENR9;K7ERZ5 P49916-4 LIG3 DNA ligase 3 1 LTTTGQVT(0.741)S(0.259)PVK;LTTTGQVT(0.936)S(0.064)PVK;LTTTGQVT(0.5)S(0.5)PVK;LTTTGQVT(0.926)S(0.073)PVK;LTTT(0.001)GQVT(0.5)S(0.5)PVK 219.74 9.0774e-11 250245000.0 441423.0 556071.0 484343.0 492013.0 485044.0 388048.0 516039.0 418361.0 388944.0 357449.0 True False 516147.19539833936 611274.053934787 495891.5740010568 464447.1067376686 390003.1101174888 367698.0797605378 467156.0501211762 407379.46704012033 394631.57019024465 422251.67413527245 1.2223686180886202 1.4476533578857036 1.1743981240964674 1.0999295803594102 0.9236271494155106 0.8708031306531708 1.1063450513911242 0.9647788084544393 0.9345885270873326 1.0 18.687743617444212 -5.733044538665716 2.0045732672650187 0.9696967243202783 1.3327815913534753 0.7534476425000912 0.08221727966016246 0.14914508715226135 1.2204616301877658 0.024579427124857382 0.04990838987698938 1.8490789786832168e-06 5.733044538665716 0.363084867033197 LTTTGQVT(ph)SPVK ddPTM_PC-9_Lapatinib_30min_R1 2 LTTTGQVTSPVK 12 0 P49916-4;P49916-3;P49916-2;P49916;K7ENR9;K7ERZ5 P49916-4 LIG3 DNA ligase 3 1 LTTTGQVT(0.723)S(0.277)PVK;LTTTGQVT(0.5)S(0.5)PVK 223.36 7.0875e-15 104895500.0 158927.0 239957.0 223532.0 215292.0 243293.0 215009.0 225989.0 217192.0 225642.0 199372.0 True False 156660.6718363579 239401.3943094139 205154.0618184727 231125.29187305892 228982.98407244185 205813.5662804591 237689.60464733045 227283.5332183785 200227.82184440191 233833.1845535087 0.669967661499768 1.0238127439718934 0.8773522124766115 0.9884195535136711 0.9792578607252514 0.8801726182425669 1.016492184807667 0.9719900691271155 0.856284886282183 1.0 17.83512015962505 -4.752552899238267 24.99914838881294 0.9529697161111707 0.6699671209636869 0.6826732281146093 0.05825858249234643 191.7990136803672 539522.7108924511 0.013640996633366365 0.1610607515551807 1.7678568708177548e-05 4.752552899238267 -0.2830025951474837 LTTTGQVT(ph)SPVKGASFVTSTNPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LTTTGQVTSPVKGASFVTSTNPR 23 1 P49916-4;P49916-3;P49916-2;P49916;K7ENR9;K7ERZ5 P49916-4 LIG3 DNA ligase 3 1 LT(0.002)T(0.015)T(0.053)GQVT(0.514)S(0.399)PVKGAS(0.014)FVT(0.003)S(0.001)T(0.001)NPR;LT(0.002)T(0.007)T(0.025)GQVT(0.517)S(0.443)PVKGAS(0.003)FVT(0.002)S(0.001)T(0.001)NPR 53.998000000000005 0.008250200000000001 110578000.0 168857.0 112794.0 149776.0 229029.0 210440.0 274960.0 210701.0 241150.0 238640.0 192827.0 True False 197441.15502222852 123991.44289042319 153347.22786864344 216197.24765203623 169205.79265617975 260540.61356058356 190741.87593686083 234820.0680195457 242129.65853747496 227785.00868230776 0.8667873103870506 0.5443353959406272 0.6732103607508129 0.9491285177312393 0.7428311179695387 1.1438005295772564 0.837376774882007 1.030884645912101 1.0629745124060106 1.0 17.7973132758666 -6.188628040194544 1.1285491386950615 1.0037275773182948 0.6811121142938734 0.47940858626384864 0.12926919057708244 0.4097126283955294 1.0767259221346566 0.05199296512631062 0.08379587972528478 6.476971108244137e-07 6.188628040194544 -0.32261546302442135 LTTTGQVTS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 2 LTTTGQVTSPVK 12 0 P49916-4;P49916-3;P49916-2;P49916;K7ENR9;K7ERZ5 P49916-4 LIG3 DNA ligase 3 1 LTTTGQVT(0.057)S(0.943)PVK;LTTTGQVT(0.202)S(0.798)PVK 120.84 0.00047439 112730000.0 54661.0 61803.0 62577.0 67428.0 57039.0 61655.0 69897.0 76108.0 65379.0 63506.0 True False 72042.06098057008 81779.61112646374 61747.18809291455 51883.51635221523 49120.11941480776 57799.703103394 76117.69759156906 64347.25738785351 68834.80046612608 61282.67426972203 1.1755697974845714 1.334465443961029 1.0075798556235986 0.8466261789402579 0.8015335492478103 0.9431654834285053 1.2420753255080543 1.0500073333066928 1.1232342792869163 1.0 15.90319163489788 -5.27511829329567 23.060847182942883 0.9973597409827665 1.2550175922249847 0.3975724000378492 0.12459644883008705 266.5401989156922 449353.3222913443 0.03663910238529726 0.077089487921298 5.307398614164059e-06 5.27511829329567 0.2576578512422182 LTTTGQVTS(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTTTGQVTSPVK 12 0 P49916-4;P49916-3;P49916-2;P49916;K7ENR9;K7ERZ5 P49916-4 LIG3 DNA ligase 3 1 LTTTGQVT(0.109)S(0.891)PVK 174.72 0.0010935 16348000.0 54880.0 70168.0 68346.0 61939.0 68681.0 42696.0 64124.0 55098.0 41477.0 43658.0 True False 64170.100070591834 77133.81531584312 69975.62784364847 58468.75863894739 55223.45108068381 40456.94659798766 58049.71050244323 53651.735881156594 42083.52265822521 51572.84980346217 1.2442612792416212 1.495628331763528 1.356830737690801 1.1337119988863265 1.0707853316451124 0.784462110435319 1.1255866356748478 1.040309699495312 0.8160014972723122 1.0 15.654324147478025 -5.977648336518873 1.980425009459589 0.9693279086932208 1.3864244362077642 0.7070122804790671 0.11344573868645673 0.1758260513967916 1.3898034321752446 0.036162240020958525 0.05876589334766354 1.052814029228668e-06 5.977648336518873 0.4170965275145434 LTTTGQVTS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 3 LTTTGQVTSPVK 12 0 P49916-4;P49916-3;P49916-2;P49916;K7ENR9;K7ERZ5 P49916-4 LIG3 DNA ligase 3 1 LTTTGQVT(0.072)S(0.928)PVK;LTTTGQVT(0.032)S(0.968)PVK;LTTTGQVT(0.182)S(0.818)PVK 199.8 6.093099999999999e-06 150150900.0 239802.0 385915.0 367674.0 332486.0 381655.0 357194.0 361827.0 346146.0 329889.0 314617.0 True False 236382.37950569854 385021.43752804736 337445.26298268314 356938.12958078174 359206.8032626 341917.6452798822 380560.6316268925 362229.20682809915 292733.4269348262 368998.12924919854 0.6406059022214188 1.0434238198211234 0.9144904438114196 0.9673169083730714 0.9734651067025164 0.926610782487117 1.031334853651481 0.9816559437987609 0.7933195421083886 1.0 18.49325397654973 -4.7520085884657846 24.997976466435063 0.9590539451425686 0.6406052753919205 0.6682564375761857 0.06731462258839963 219.2853696740542 581213.2760951896 0.01603821998652133 0.20016217715863602 1.770073953567101e-05 4.7520085884657846 -0.3184486697506481 LTTTGQVTS(ph)PVKGASFVTSTNPR ddPTM_PC-9_AZD4547_30min_R2 2 LTTTGQVTSPVKGASFVTSTNPR 23 1 P49916-4;P49916-3;P49916-2;P49916;K7ENR9;K7ERZ5 P49916-4 LIG3 DNA ligase 3 1 LT(0.003)T(0.005)T(0.012)GQVT(0.278)S(0.606)PVKGAS(0.036)FVT(0.02)S(0.02)T(0.02)NPR;LTTT(0.002)GQVT(0.137)S(0.816)PVKGAS(0.01)FVT(0.014)S(0.014)T(0.006)NPR 72.05199999999999 0.00035446 144865000.0 101676.0 72319.0 93165.0 149319.0 119408.0 89014.0 91162.0 88386.0 83124.0 90020.0 True False 134006.85300781982 95694.70247487554 91929.57122707042 114895.81150555293 102830.2603321126 83447.94050840192 99275.24139580551 74727.9746082252 87517.76493899066 86868.42719995535 1.5426416400904828 1.1016051004883938 1.05826218098165 1.3226417837758664 1.1837472329896799 0.9606245122444765 1.1428230554617034 0.8602432093793406 1.0074749567819463 1.0 16.406544296534676 -1.5228787452803376 0.31471191904134593 0.9761837406266782 5.026576093465586 0.5272369011491447 0.12832500085261705 49.90600460046575 0.7125977947135474 0.1284313217011098 115.67899839897181 0.029999999999999995 1.5228787452803376 4.050392352838908 LTTTGQVTS(ph)PVKGASFVTSTNPR ddPTM_PC-9_Lapatinib_30min_R1 2 LTTTGQVTSPVKGASFVTSTNPR 23 1 P49916-4;P49916-3;P49916-2;P49916;K7ENR9;K7ERZ5 P49916-4 LIG3 DNA ligase 3 1 LTT(0.002)T(0.007)GQVT(0.265)S(0.687)PVKGAS(0.024)FVT(0.01)S(0.004)T(0.001)NPR;LTTT(0.001)GQVT(0.291)S(0.705)PVKGAS(0.002)FVT(0.001)STNPR 72.051 0.00035453 98841000.0 221450.0 132449.0 152803.0 129468.0 102869.0 109001.0 101674.0 75113.0 128483.0 90552.0 True False 218292.08239104325 132142.32247814254 140240.12717663753 138989.508612587 96818.44766823541 104339.28132374142 106938.18222529718 78603.02419348784 114011.89155402932 106203.79254704436 2.055407600386285 1.2442335561567481 1.320481348295696 1.308705699478856 0.9116289102891351 0.9824440240919172 1.0069149101048112 0.7401150402295624 1.0735199640213062 1.0 16.69647576026926 -1.522878745298983 0.5447663105245627 0.9405876314834416 45.19555985671088 0.8247644888545818 0.14395366815326524 51.746447320640605 0.4818430070601495 0.07171465228793514 2674.0200980569152 0.029999999998712022 1.522878745298983 44.25497222522744 up LTVADIR ddPTM_PC-9_AZD4547_30min_R2 1 LTVADIR 7 0 P11413;P11413-2;P11413-3;E7EUI8;E7EM57;E9PD92 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 97.473 0.019500999999999998 0.0 34328.0 38456.0 46052.0 56597.0 48179.0 45505.0 39652.0 55643.0 41599.0 42548.0 False True 45243.589933243195 50886.1499519326 45441.32039015774 43549.436064933354 41490.177480075436 42659.565156434124 43180.95118389763 47044.65289893744 43797.83821395834 41058.40747060326 1.1019324109352369 1.2393600503956648 1.1067482445024817 1.0606703656519947 1.0105159950439215 1.0389970723286637 1.0516957145698858 1.1457982858351283 1.0667203360314557 1.0 15.325390050375903 -5.521003606207071 4.493091870732417 1.058054520058049 1.1723564783318534 0.4816856828092454 0.048365629574178025 0.16091925022744977 8.263312432718259 0.01330171158377527 0.026138172502754593 3.01298100549726e-06 5.521003606207071 0.11430195827380452 LTVADIR ddPTM_PC-9_Lapatinib_30min_R1 1 LTVADIR 7 0 P11413;P11413-2;P11413-3;E7EUI8;E7EM57;E9PD92 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 110.34 0.043677999999999995 11933000.0 95695.0 107830.0 104400.0 107800.0 104200.0 107450.0 105500.0 99147.0 100330.0 106010.0 False True 94330.37175168628 107580.32626005566 95816.6349956542 115727.9716102583 98071.16086508222 102854.61397818376 110962.27378453534 103753.73157391831 89029.7788782622 124333.68725055417 0.758687157420129 0.8652548527999693 0.7706409832643899 0.9307853259193235 0.7887738474887472 0.8272465512175609 0.892455425703952 0.8344780394458693 0.716055164509451 1.0 16.92385771084946 -10.985175299742785 3.530227506557413 1.0021952388082276 0.8253755021020095 0.43089259099450117 0.06166156595063229 86842993.82827097 140583230.25120696 1936239.722974859 0.014725079201984447 1.0347244235452963e-11 10.985175299742785 -0.1768197367062181 LTVAS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LTVASPK 7 0 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 LTVAS(1)PK;LTVAS(1)PK 91.087 0.015491999999999999 29638000.0 300320.0 320720.0 266000.0 355550.0 340980.0 272190.0 348680.0 323810.0 315870.0 242507.0 True False 351158.2444096233 352558.96203536063 272342.44881061715 335629.6862086528 274167.41674541123 257915.8772368901 315650.5061754087 315310.3306050547 320489.00118266983 286471.59941564454 1.22580473989718 1.2306942913521743 0.9506787038092134 1.171598465234539 0.9570492059410711 0.9003191861357166 1.1018561938401028 1.1006687268414617 1.118746157861426 1.0 18.128032592779633 -5.243373794030989 24.24371553015299 1.040508634720454 1.2282495934369257 0.4642326885424459 0.08187142222078489 510.7009915714555 685347.9222260204 0.02151523355543324 0.0566402568410457 5.709869808716215e-06 5.243373794030989 0.18774095871647178 LTVAS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 LTVASPK 7 0 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 LTVAS(1)PK 81.525 0.023815 32073000.0 295720.0 268890.0 216850.0 286250.0 267430.0 209410.0 213010.0 194540.0 212280.0 189140.0 True False 291502.9785715937 268267.40172555216 199021.43006520718 307301.77990200743 251700.2931876097 200454.02245855262 224038.61553406515 203579.03860318672 188370.7909925 221832.59698679234 1.314067375720032 1.209323631285462 0.8971694546634041 1.3852868517799655 1.1346407002691117 0.9036274433125238 1.0099445193232992 0.9177147153684884 0.8491573986473926 1.0 17.759111851008647 -6.680221271291129 5.023338010126821 0.9357289609583113 1.188724738088726 0.5027986316883402 0.1261283595883133 0.18609510199413537 8.223360373989049 0.042756500406408694 0.04227570553151338 2.088231914011856e-07 6.680221271291129 0.25299577713041477 LTVENS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 LTVENSPK 8 0 F8VVL1;O43583 F8VVL1 DENR Density-regulated protein 1 LTVENS(1)PK;LTVENS(1)PK 103.21 0.0040413 98433500.0 650998.0 671798.0 431704.0 439009.0 384232.0 639700.0 705182.0 608816.0 547335.0 495984.0 True False 858001.8224004171 888943.5657740906 425979.32288961735 337802.2576714373 330888.0191270958 599699.4578743182 767941.8318814521 514737.4763998984 576266.0106934509 478619.75112578005 1.7926586196709973 1.8573064811537174 0.890016180668798 0.7057841989948795 0.6913379950342653 1.2529768286071394 1.6044925644525667 1.0754622540945384 1.2040163602483878 1.0 18.868520408010383 -5.255191722305412 24.681161600400937 1.057225459118204 1.824982673733455 0.5944506511481595 0.2550309953115255 319.9625276384166 1263990.0792716648 0.07488830286345839 0.18781742537510485 5.556589036483321e-06 5.255191722305412 0.7677572146152509 LTVENS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LTVENSPK 8 0 F8VVL1;O43583 F8VVL1 DENR Density-regulated protein 1 LT(0.001)VENS(0.999)PK;LTVENS(1)PK;LTVENS(1)PK;LT(0.001)VENS(0.999)PK 108.9 0.0037865999999999998 98237000.0 659082.0 1004490.0 522255.0 580867.0 556726.0 384960.0 623149.0 386056.0 385539.0 427353.0 True False 770651.5651371308 1104209.1287568589 534707.5398631176 548322.9051862216 447639.5367910298 364772.01991665066 564119.8155119304 375922.4390601441 391176.7785068715 504828.71597551403 1.5265604763547367 2.187294608673602 1.0591860624050808 1.0861563295318113 0.8867156772689252 0.7225659087395166 1.1174479534545578 0.7446534382136409 0.774870299822336 1.0 18.9454344513523 -5.380487267061559 5.06542720983318 0.9070092679591255 1.8499585387702133 0.7833358274134817 0.19721628355606607 0.08732778684572227 3.2233280815265157 0.05052259393145455 0.10873940014391903 4.16401929198716e-06 5.380487267061559 0.9429492708110878 LTVENS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 LTVENSPK 8 0 F8VVL1;O43583 F8VVL1 DENR Density-regulated protein 1 LTVENS(1)PK;LT(0.001)VENS(0.999)PK;LT(0.001)VENS(0.999)PK;LT(0.381)VENS(0.619)PK 111.5 0.0037450000000000005 431122000.0 2005360.0 2255220.0 1143701.0 1477830.0 1653180.0 1520340.0 2004670.0 1771650.0 1289714.0 1355500.0 True False 1976763.1986620123 2249998.1766503 1049670.3185935314 1586514.548096361 1555943.202676935 1455318.6022856387 2108462.003674358 1853967.326726303 1144452.828029495 1589796.3689097848 1.2434065376672063 1.4152744468735037 0.6602545704097632 0.9979356973775992 0.978705973359302 0.9154119551069516 1.3262465840957054 1.1661665374148988 0.7198738469973437 1.0 20.600410557237794 -5.230532368406658 24.98739420653353 0.9885089536191765 1.3293405823667592 0.37020235210342445 0.18600383433710854 769.3098865587912 621961.6734195871 0.04839942495952681 0.12802331461593242 5.8812227916167136e-06 5.230532368406658 0.34083162874758277 LTVENS(ph)PKQEAGISEGQGTAGEEEEK ddPTM_PC-9_AZD4547_30min_R2 3 LTVENSPKQEAGISEGQGTAGEEEEK 26 1 F8VVL1;O43583 F8VVL1 DENR Density-regulated protein 1 LT(0.01)VENS(0.988)PKQEAGIS(0.001)EGQGTAGEEEEK;LT(0.001)VENS(0.998)PKQEAGIS(0.001)EGQGTAGEEEEK;LT(0.004)VENS(0.991)PKQEAGIS(0.002)EGQGT(0.003)AGEEEEK 102.69 7.4077e-10 182826400.0 114448.0 134878.0 101682.0 87451.0 87804.0 108745.0 123233.0 112885.0 98481.0 92655.0 True False 150840.08333371647 178474.67581695333 100333.63024216135 67290.52305448145 75613.93020736317 101945.15795926665 134200.4982660457 95441.2170892393 103686.5046070539 89411.17665198693 1.6870383433251064 1.9961114762153978 1.1221598238516381 0.7525963260319771 0.8456876761802782 1.1401836076496952 1.5009364968810468 1.0674416852909 1.1596593232480374 1.0 16.44816756322369 -5.272385938999556 21.459742594408755 1.074029741682591 1.8415748572415964 0.699699122661811 0.2012513638821888 54.661981354919575 107161.84727267794 0.05784630433584486 0.12302477373869003 5.340895258434897e-06 5.272385938999556 0.7675451155590054 LTVENS(ph)PKQEAGISEGQGTAGEEEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LTVENSPKQEAGISEGQGTAGEEEEK 26 1 F8VVL1;O43583 F8VVL1 DENR Density-regulated protein 1 LT(0.012)VENS(0.987)PKQEAGISEGQGTAGEEEEK;LT(0.005)VENS(0.995)PKQEAGISEGQGTAGEEEEK;LT(0.095)VENS(0.903)PKQEAGIS(0.001)EGQGTAGEEEEK;LT(0.022)VENS(0.936)PKQEAGIS(0.019)EGQGT(0.023)AGEEEEK 74.905 3.8751e-05 87232000.0 127887.0 145076.0 83137.0 123693.0 129872.0 93936.0 127085.0 102433.0 98629.0 86179.0 True False 149535.74321661386 159478.1865061174 85119.30137882827 116762.88222811655 104424.51389395287 89009.83079512294 115046.58878427731 99744.2422867346 100071.26253726362 101802.57050741147 1.4688798374273595 1.5665438083855359 0.8361213371584894 1.146954164773432 1.0257551786116297 0.8743377534719795 1.1300951263887944 0.9797811763453752 0.9829934749042334 1.0 16.635414464253913 -5.253321051409292 24.992275833586785 1.003037071166389 1.5177118891680217 0.8320344610040744 0.09355071085910474 212.02917811709983 652728.2374285031 0.022801497195413273 0.058174027572224236 5.580574992176963e-06 5.253321051409292 0.5146748180016327 LTVENS(ph)PKQEAGISEGQGTAGEEEEK ddPTM_PC-9_Lapatinib_30min_R1 6 LTVENSPKQEAGISEGQGTAGEEEEK 26 1 F8VVL1;O43583 F8VVL1 DENR Density-regulated protein 1 LT(0.002)VENS(0.998)PKQEAGISEGQGTAGEEEEK;LT(0.001)VENS(0.999)PKQEAGISEGQGTAGEEEEK;LT(0.001)VENS(0.999)PKQEAGISEGQGTAGEEEEK;LTVENS(1)PKQEAGISEGQGTAGEEEEK;LT(0.03)VENS(0.969)PKQEAGISEGQGTAGEEEEK;LT(0.006)VENS(0.987)PKQEAGIS(0.005)EGQGT(0.003)AGEEEEK 113.65 8.8003e-12 254289400.0 259634.0 335316.0 240341.0 268721.0 322509.0 294019.0 339775.0 316342.0 242074.0 252003.0 True False 255931.5715489557 334539.59640375373 220581.09072308906 288483.63876697695 303539.65469708986 281444.4927617648 357366.88696815626 331040.404183249 214809.07696777084 295561.38277710974 0.8659168161422499 1.1318785737852581 0.7463122842723834 0.9760532179690393 1.026993620902081 0.9522370281167928 1.209112244672558 1.1200394350330092 0.7267832994602131 1.0 18.17309825773873 -5.996094902815525 24.993173179897244 1.0177242147560392 0.923880612384468 0.06745864966755333 0.14648771434909036 325.1603894688097 2081026.7033119637 0.041156904550021696 0.06073056386089521 1.0090323664060323e-06 5.996094902815525 -0.0938436023715713 LTVENS(ph)PKQEAGISEGQGTAGEEEEKK ddPTM_PC-9_Lapatinib_30min_R1 1 LTVENSPKQEAGISEGQGTAGEEEEKK 27 2 F8VVL1;O43583 F8VVL1 DENR Density-regulated protein 1 LT(0.012)VENS(0.848)PKQEAGIS(0.139)EGQGT(0.001)AGEEEEKK 54.958 0.0013397 6465500.0 9248.1 9394.2 22205.0 10466.0 12079.0 17916.0 7402.4 8452.7 19862.0 8153.0 True False 9116.22039810617 9372.448307077922 20379.39061377873 11235.704553552525 11368.536968227698 17149.77444423584 7785.660051778626 8845.443300098455 17624.93240386769 9562.235186810369 0.9533566389039032 0.9801524564053572 2.1312371235010996 1.1750081789507174 1.1888995351117115 1.7934901316683065 0.8142092198817433 0.9250392954462554 1.8431812290267207 1.0 13.22313217441717 -7.277248829766635 24.99010069045282 1.1393607755637118 1.3700786491439678 0.06232116002069654 0.42680903874619 2733.5951742636826 4320995.080221665 0.18012263385838134 0.12188810082905582 5.281425648845888e-08 7.277248829766635 0.23071787358025597 LTVENS(ph)PKQEAGISEGQGTAGEEEEKKK ddPTM_PC-9_AZD4547_30min_R2 1 LTVENSPKQEAGISEGQGTAGEEEEKKK 28 3 F8VVL1;O43583 F8VVL1 DENR Density-regulated protein 1 LT(0.006)VENS(0.989)PKQEAGIS(0.001)EGQGT(0.004)AGEEEEKKK 61.903 0.0008757999999999999 10235000.0 28169.0 17296.0 12794.0 18782.0 20584.0 17062.0 20530.0 12006.0 21420.0 22322.0 True False 37126.15604840153 22886.593758285468 12624.343200548907 14452.100079007343 17726.26690570317 15995.110442788247 22357.1302281201 10150.748570433705 22552.217470203308 21540.513574288016 1.7235501800067303 1.0624906262961256 0.5860743829069165 0.6709264395746902 0.8229268464082607 0.7425593817726297 1.037910732769475 0.47123985857747686 1.046967491857897 1.0 14.39476502693601 -4.825879949615434 3.037478091889615 0.7822027202284091 1.8257397837966254 0.6970065081101064 0.18406169319908264 0.16729993591252953 2.4013383864805764 0.04410606219722013 0.4051071033835964 1.4932071141422504e-05 4.825879949615434 1.0435370635682162 LTVENS(ph)PKQEAGISEGQGTAGEEEEKKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTVENSPKQEAGISEGQGTAGEEEEKKK 28 3 F8VVL1;O43583 F8VVL1 DENR Density-regulated protein 1 LT(0.114)VENS(0.886)PKQEAGISEGQGTAGEEEEKKK 57.768 0.0033187 23016000.0 95760.0 47952.0 39502.0 107530.0 91824.0 83807.0 100620.0 115540.0 91107.0 80237.0 True False 111970.27665378767 52712.35765627228 40443.87749216925 101505.44271696388 73831.74636409942 79412.01338620832 91088.54517428482 112507.1974247493 92439.26751748956 94783.33294425759 1.181328754493554 0.5561353037381858 0.4266981993126834 1.0709207997218202 0.778952839815415 0.8378267667893763 0.9610185920329929 1.1869934716361492 0.9752692234599243 1.0 16.532345772083687 -7.317529901694614 2.5089079498646467 1.0626441993604956 0.784875651242862 0.21256217034754354 0.21201205500622372 0.4375752976475875 5.40607527749297 0.10440898191295972 0.06648647224254108 4.813601106397224e-08 7.317529901694614 -0.27776854811763363 LTVENS(ph)PKQEAGISEGQGTAGEEEEKKK ddPTM_PC-9_Lapatinib_30min_R1 1 LTVENSPKQEAGISEGQGTAGEEEEKKK 28 3 F8VVL1;O43583 F8VVL1 DENR Density-regulated protein 1 LT(0.015)VENS(0.982)PKQEAGIS(0.003)EGQGTAGEEEEKKK 57.981 0.0032225 34583000.0 396270.0 211950.0 186240.0 255490.0 214830.0 241350.0 199370.0 212760.0 196380.0 191690.0 True False 390619.1171329825 211459.2427971696 170928.06610719016 274279.5868896558 202194.12177203078 231028.02311432883 209692.40307509815 222645.6063185665 174261.6164269225 224823.3610891308 1.7374489698965148 0.9405572524704716 0.760277158384026 1.219978144446111 0.8993465838804504 1.0275979417580996 0.9326984618469697 0.9903134853957596 0.775104578023975 1.0 17.778432426260622 -4.7609277602771485 24.999999756339374 0.9521197191091634 1.737449860410924 0.7854173592436413 0.12354359971543596 5.298618372316153 258667.25413476172 0.029423351309410352 0.16903276311214924 1.7340924194195237e-05 4.7609277602771485 0.7853301413017607 LTVLSEER ddPTM_PC-9_Lapatinib_30min_R1 1 LTVLSEER 8 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 101.6 0.020899 2108200.0 15336.0 16739.0 16106.0 16369.0 18910.0 16532.0 17492.0 14495.0 20944.0 15104.0 False True 15117.305827722048 16700.2418739411 14781.826850957907 17572.830865383257 17797.75097849042 15824.964897974267 18397.65017098667 15168.490616599083 18585.06616990258 17714.70627518506 0.8533760364346837 0.9427332079073175 0.8344381567118863 0.9919910944275411 1.004687896147716 0.8933235839276679 1.0385523691554674 0.8562654317247844 1.0491320534022475 1.0 14.112659924099834 -1.5228787665221621 0.2857157972071654 0.9864827381531084 0.01805778096616865 0.25825602291448113 0.06645479485003655 78.8105594138956 1.1154663173062338 0.06882919516667965 38.36354718045883 0.02999999853266678 1.5228787665221621 -0.9684249571869398 LTVNGVCAS(ph)TPPLTPIK ddPTM_PC-9_AZD4547_30min_R2 1 LTVNGVCASTPPLTPIK 17 0 Q9UJM3 Q9UJM3 ERRFI1 ERBB receptor feedback inhibitor 1 1 LTVNGVCAS(0.655)T(0.343)PPLT(0.001)PIK 70.41 0.014759 4602900.0 17947.0 19712.0 32722.0 34805.0 35079.0 32324.0 22409.0 32005.0 28129.0 31821.0 True False 23653.77267920986 26083.51851083045 32288.08489982503 26781.2449818896 30208.886357615687 30302.77517012584 24403.357588014787 27059.362651735024 29615.84151350834 30706.956475558596 0.7703066469005886 0.8494335324828365 1.0514908869436457 0.8721556303766642 0.9837798930565017 0.9868374677329397 0.7947175620429462 0.8812127855547358 0.9644668476695587 1.0 14.906277906021085 -5.0127928530648695 11.837857576605723 0.9341267853989373 0.7899616838297239 0.3725880974193123 0.07123174515557038 0.6530775289376602 613.1320947779442 0.018193554404941584 0.05506235853649171 9.7097298514271e-06 5.0127928530648695 -0.14416510156921347 LTVVS(ph)PNR ddPTM_PC-9_AZD4547_30min_R2 1 LTVVSPNR 8 0 Q14CZ0;A0A087X1J2 Q14CZ0 C16orf72 UPF0472 protein C16orf72 1 LT(0.002)VVS(0.998)PNR 84.81700000000001 0.013691 14195000.0 39393.0 37506.0 51550.0 53093.0 58228.0 56844.0 53059.0 57157.0 54063.0 51007.0 True False 51919.154574698485 49629.08103019512 50866.413317828345 40853.22912867301 50144.04728844168 53289.53569393123 57781.148211097156 48324.69898719635 56920.65980819803 49221.2604553225 1.054811560988464 1.0082854557380299 1.0334236231922407 0.8299915270506929 1.0187477286152957 1.0826528049256572 1.173906309521357 0.981785077020936 1.1564242622324588 1.0 15.586993982273588 -6.644026246895144 4.625763234180318 1.0833769484170246 0.9805924381808288 0.24970733391673738 0.07927346634138985 0.2958833438331148 10.652186521221319 0.0266391311300829 0.026491065322514117 2.269727675136269e-07 6.644026246895144 -0.10278451023619584 LTVVS(ph)PNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LTVVSPNR 8 0 Q14CZ0;A0A087X1J2 Q14CZ0 C16orf72 UPF0472 protein C16orf72 1 LT(0.003)VVS(0.997)PNR;LTVVS(1)PNR 77.533 0.023407 19922500.0 73086.0 75624.0 101436.0 94653.0 97582.0 84511.0 90694.0 90501.0 92475.0 71245.0 True False 85458.01628570128 83131.45093839541 103854.61893817225 89349.89927916629 78461.50759824824 80079.09438688729 82102.80775230155 88125.44464373562 93827.27192948785 84161.15452489033 1.0154092677094562 0.9877650967087152 1.233997080059752 1.061652490196548 0.9322769874199333 0.951497099094621 0.975542793059237 1.0471035615091624 1.1148524810426501 1.0 16.360866875243225 LTWHS(ph)CPEDEAQ ddPTM_PC-9_AZD4547_30min_R2 5 LTWHSCPEDEAQ 12 0 Q13185 Q13185 CBX3 Chromobox protein homolog 3 1 LTWHS(1)CPEDEAQ;LTWHS(1)CPEDEAQ;LTWHS(1)CPEDEAQ;LTWHS(1)CPEDEAQ;LTWHS(1)CPEDEAQ 124.38 0.00032419 212759900.0 344203.0 297617.0 435974.0 591684.0 482350.0 402237.0 365628.0 443710.0 331437.0 439834.0 True False 453652.39413283975 393815.87503235665 430192.69989964913 455280.39522667293 415384.0284670587 377085.0568031773 398168.18368471024 375144.81494145707 348956.0831779541 424435.5455350504 1.0688369504042319 0.9278579025135746 1.0135642606401902 1.072672635494605 0.97867398910574 0.8884389179229032 0.9381122478391222 0.8838675716204292 0.8221650774749658 1.0 18.69518595825719 -6.630860582295273 4.310915395216349 0.901476874321742 1.0149051663066702 0.4767739044972763 0.05639430938125334 0.1941310162677676 6.409587963002088 0.018939431394038305 0.01888433244591742 2.3395881753561558e-07 6.630860582295273 0.11342829198492821 LTWHS(ph)CPEDEAQ ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LTWHSCPEDEAQ 12 0 Q13185 Q13185 CBX3 Chromobox protein homolog 3 1 LTWHS(1)CPEDEAQ;LTWHS(1)CPEDEAQ;LTWHS(1)CPEDEAQ;LTWHS(1)CPEDEAQ;LTWHS(1)CPEDEAQ;LTWHS(1)CPEDEAQ 124.21 0.0003292 119172100.0 201053.0 211874.0 230454.0 245064.0 287781.0 238621.0 233716.0 244558.0 229950.0 182661.0 True False 235087.30192224256 232907.4504935149 235948.89736166227 231333.8585882077 231392.3789031936 226107.2946917373 211576.7285226902 238138.6116306202 233312.58372734013 215775.99335631926 1.0894970208017247 1.0793946391844702 1.0934900295976426 1.0721019284392639 1.0723731370852103 1.047879753325281 0.9805387764954248 1.1036381199152803 1.0812722031688762 1.0 17.719174837907914 -6.620533610408087 2.9402827240901237 1.0452836128342589 1.083364995317437 0.25366016990237994 0.033508549818271754 0.4393752589026303 7.659983306426527 0.012311154934178463 0.012374363228617723 2.395887322874851e-07 6.620533610408087 0.03808138248317805 LTWHS(ph)CPEDEAQ ddPTM_PC-9_Lapatinib_30min_R1 6 LTWHSCPEDEAQ 12 0 Q13185 Q13185 CBX3 Chromobox protein homolog 3 1 LTWHS(1)CPEDEAQ;LT(0.001)WHS(0.999)CPEDEAQ;LTWHS(1)CPEDEAQ;LTWHS(1)CPEDEAQ;LT(0.001)WHS(0.999)CPEDEAQ;LTWHS(1)CPEDEAQ 161.87 8.406100000000001e-05 180424000.0 233686.0 283564.0 357266.0 318134.0 339242.0 333193.0 274333.0 287972.0 353297.0 261496.0 True False 230353.59478723584 282907.4249801204 327892.96856664115 341530.6356239135 319288.4525354339 318943.11210081866 288536.62041832175 301352.23041347146 313504.9714776585 306695.235178482 0.751083056941465 0.9224382792105712 1.0691166048791827 1.1135831159070957 1.0410610140376757 1.0399350088214085 0.9407926414324865 0.9825787813041791 1.0222035933985525 1.0 18.226446227485262 -4.876845410534305 2.840444818828266 1.0260611113888225 0.7298326346666646 0.7781213789667123 0.0451468486896146 0.1728958710185469 2.2439023188992633 0.013354421263688155 0.10830479864479281 1.3278670350571309e-05 4.876845410534305 -0.2962284767221579 LTWHSCPEDEAQ ddPTM_PC-9_Lapatinib_30min_R1 1 LTWHSCPEDEAQ 12 0 Q13185 Q13185 CBX3 Chromobox protein homolog 3 0 106.88 0.007456399999999999 4966800.0 24287.0 28440.0 28332.0 25298.0 27749.0 26826.0 24322.0 21778.0 26894.0 26869.0 False True 23940.662926309677 28374.148927348397 26002.6523246827 27158.499311654065 26116.858376633045 25678.714514460284 25581.27415154 22789.885384497735 23864.91451362489 31513.270849307966 0.7597009856828434 0.9003873023219199 0.8251334001165328 0.8618115028910263 0.8287574622615403 0.8148539907917616 0.811761948604639 0.7231837499025653 0.7572972868396797 1.0 14.943671882974309 -6.8382959411712605 2.3094443171686487 0.801048277131714 0.840636241753722 0.0 0.07650498689329695 1.0363871460423228 11.308934394690358 0.029055880680723085 0.025543395954338785 1.4511224426260768e-07 6.8382959411712605 0.039587964622007976 LTYHGVS(ph)PCK ddPTM_PC-9_AZD4547_30min_R2 1 LTYHGVSPCK 10 0 Q9UBS8-2;Q9UBS8 Q9UBS8-2 RNF14 E3 ubiquitin-protein ligase RNF14 1 LTYHGVS(1)PCK 59.79600000000001 0.040239 10327000.0 38101.0 42350.0 50371.0 58015.0 61062.0 55640.0 50172.0 64039.0 44599.0 60512.0 True False 50216.32544996793 56038.80930061229 49703.04762817325 44640.53807281496 52584.59530684252 52160.822004263115 54637.210803957205 54143.2440198238 46956.412089336925 58393.49329841933 0.8599644003714237 0.9596755757396898 0.8511744172277269 0.7644779503887524 0.9005214851269387 0.8932642843903136 0.9356729271998563 0.9272136493551657 0.8041377461246697 1.0 15.833520000211527 -6.493196007074774 24.943050418602677 0.907641043974238 0.8613579083712073 0.13685418969466656 0.06306854154885545 1641.2571242022473 1379185.2306652465 0.019986111791991237 0.02262836917492765 3.2122104670761963e-07 6.493196007074774 -0.046283135603030656 LTYHGVS(ph)PCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LTYHGVSPCK 10 0 Q9UBS8-2;Q9UBS8 Q9UBS8-2 RNF14 E3 ubiquitin-protein ligase RNF14 1 LTYHGVS(1)PCK 64.22399999999999 0.029454 3308400.0 46433.0 46595.0 40865.0 44815.0 50979.0 39057.0 46708.0 35792.0 35161.0 29946.0 True False 54293.189806446615 51220.64366437282 41839.37658137551 42304.160842190315 40990.03090581352 37008.78216408106 42283.48010336408 34852.49792475871 35675.16310692328 35374.97274759444 1.5347910002316156 1.4479345052740973 1.1827394717702124 1.1958782595830288 1.1587296815260701 1.0461854607816687 1.1952936446075266 0.9852303823224497 1.0084859530909251 1.0 15.110441416061446 -1.5228787453650192 0.3409687140632081 1.0084340131192828 7.2880027299061245 0.887742345757466 0.05956616305466729 18.051429893402915 0.2556448816985923 0.05193865519559168 72.23216105345344 0.0299999999941504 1.5228787453650192 6.279568716786842 LVAAASPS(ph)AMLSQSLDLSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LVAAASPSAMLSQSLDLSDR 20 0 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 LVAAAS(0.333)PS(0.667)AMLSQSLDLSDR 148.19 1.4957e-14 0.0 10552.0 12741.0 12604.0 16409.0 22617.0 18588.0 20294.0 16888.0 22270.0 16695.0 True False 12338.245188500085 14005.842277664433 12904.52716093618 15489.656928695771 18185.361207492973 17613.21255769615 18371.60540416353 16444.70789431509 22595.656619299265 19721.67134245272 0.6256186392246013 0.7101752196587702 0.6543323299966973 0.7854129936418144 0.9221004088201847 0.8930892444081088 0.9315440403175643 0.8338394656702516 1.145727267580006 1.0 14.267494199789276 -5.990550603764226 0.46253904004475344 1.0167261574901736 0.5503276279401327 0.7644179332085199 0.07460712093583265 0.8788797318051516 0.31235809880924537 0.06261565473426316 0.20148873470446388 1.0219964711716999e-06 5.990550603764226 -0.4663985295500409 LVAAASPSAMLS(ph)QSLDLSDR ddPTM_PC-9_AZD4547_30min_R2 1 LVAAASPSAMLSQSLDLSDR 20 0 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 LVAAAS(0.058)PS(0.027)AMLS(0.872)QS(0.027)LDLS(0.015)DR 67.994 0.0046577 4719700.0 27523.0 30200.0 36966.0 66793.0 55714.0 46827.0 47104.0 67902.0 51039.0 51106.0 True False 36274.74148603628 39961.55940681206 36475.80668684466 51394.905791563106 47979.072793642954 43898.90028744841 51296.16474746073 57409.306132732825 53736.817341816386 49316.794495455724 0.7355454030853282 0.8103032611029556 0.7396224158527925 1.042138004251247 0.9728749259659195 0.8901409902359622 1.040135825376635 1.164092409493946 1.0896251042181573 1.0 15.58979140970787 -5.738288643109653 0.5568645717056128 1.083245864729857 0.6649596697896764 0.6829132621969445 0.07929415107387573 0.974673387283289 0.46959305200917206 0.0561679683626482 0.23501334518538147 1.826885618119896e-06 5.738288643109653 -0.4182861949401807 LVAAASPSAMLSQS(ph)LDLSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LVAAASPSAMLSQSLDLSDR 20 0 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 LVAAAS(0.022)PS(0.061)AMLS(0.102)QS(0.782)LDLS(0.033)DR 64.12100000000001 0.0061888 2655300.0 5856.4 5783.2 6026.1 6389.4 9758.2 10662.0 10019.0 8576.0 8074.6 10233.0 True False 6847.77285082751 6357.3178761627005 6169.785078111518 6031.422632714287 7846.150759824818 10102.865950621708 9069.927788721512 8350.8890870231 8192.6757493576 12088.161895616573 0.5664858652588579 0.5259127012906735 0.5103989449668782 0.4989528337555944 0.6490772399954372 0.8357652749741236 0.750314883854299 0.6908320023453121 0.677743714892538 1.0 13.561307267173358 -6.5028305571681555 3.846059379698853 0.7685553591413742 0.5263119170793088 0.6696628421312903 0.08715813674948851 0.14387263820087112 4.679744734366635 0.028227332722066418 0.03040494059565417 3.1417342229365816e-07 6.5028305571681555 -0.24224344206206538 LVAIVDVIDQNR ddPTM_PC-9_Lapatinib_30min_R1 2 LVAIVDVIDQNR 12 0 E7EPB3;P50914 E7EPB3 RPL14 60S ribosomal protein L14 0 ; 178.54 0.002617 25704000.0 9966.8 14539.9 14931.2 13506.5 10116.3 17215.6 15652.3 8173.5 23768.4 14441.8 False True 9824.671604312727 14506.233754878787 13703.614372098764 14499.813066363185 9521.279123411043 16479.328919523694 16462.699506707908 8553.270648828746 21091.352499652054 16938.045887511104 0.5800357177894253 0.8564290031575981 0.8090434081420704 0.8560499341340375 0.5621238238840378 0.9729179522222434 0.9719361735137533 0.5049738739422894 1.245205771652992 1.0 14.047979822636727 -8.277873164240772 24.995564062471786 1.1226029089843081 0.7789676561112772 0.4217322972875287 0.16716184702954157 901.6216846189706 1371340.8989156552 0.15266966084206324 0.03987562493957409 5.273838614583485e-09 8.277873164240772 -0.343635252873031 LVALTLAR ddPTM_PC-9_AZD4547_30min_R2 2 LVALTLAR 8 0 Q5SZD4 Q5SZD4 GLYATL3 Glycine N-acyltransferase-like protein 3 0 ; 82.671 0.013544999999999998 7959700.0 44195.0 40425.0 57471.0 77414.0 61903.0 57190.0 46590.0 61684.0 47916.0 54705.0 False True 58248.09068689359 53491.59069603901 56708.89698911568 59567.3983343773 53308.83697355926 53613.900259234535 50736.41974321068 52152.15515730739 50448.74193754725 52789.79460090609 1.103396804766007 1.0132941622606897 1.0742397733849551 1.1283885225299755 1.0098322483839377 1.015611079083727 0.9611028064568343 0.9879211607391297 0.9556533098668534 1.0 15.687971432206396 -6.6090835751970545 2.3597682438330563 0.9792740308788274 1.07410551118485 0.6488026011091077 0.03278563806694431 0.1918361866597272 2.172334198062173 0.0120243771221879 0.012217933040957495 2.4598941790133543e-07 6.6090835751970545 0.09483148030602273 LVALTLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LVALTLAR 8 0 Q5SZD4 Q5SZD4 GLYATL3 Glycine N-acyltransferase-like protein 3 0 68.78699999999999 0.031301 0.0 12672.0 14292.0 18533.0 20592.0 23607.0 20437.0 20803.0 18325.0 18616.0 14606.0 False True 14817.119316591474 15710.815307462519 18974.897006793908 19438.297000164745 18981.377814267446 19365.247742717682 18832.389239322652 17843.988166942436 18888.2237819881 17253.95217896762 0.8587666850412037 0.9105632810675014 1.0997420654685772 1.1265996798032059 1.1001176783951876 1.1223659102477235 1.0914826379476774 1.034197149838752 1.0947186816138648 1.0 14.074639242073497 -5.191620102718407 4.029481649124039 1.0890142202959616 0.8716174949083642 0.8174934859202585 0.03777732404364882 0.08419456306913127 2.6550296765908548 0.009784303159849805 0.028753863348541537 6.432501516673637e-06 5.191620102718407 -0.21739672538759747 LVALTLAR ddPTM_PC-9_Lapatinib_30min_R1 1 LVALTLAR 8 0 Q5SZD4 Q5SZD4 GLYATL3 Glycine N-acyltransferase-like protein 3 0 89.296 0.0086715 3365000.0 36909.0 39081.0 36671.0 37808.0 39946.0 38416.0 35170.0 31185.0 38197.0 32257.0 False True 36382.67089171838 38990.510345629504 33656.05193415356 40588.52644379073 37596.45481685765 36773.03723206989 36990.93051186837 32633.96894643962 33894.85162775827 37832.57947024926 0.9616756615902688 1.0306067122991394 0.8896050019697962 1.0728458649167365 0.9937586953705525 0.9719939202397613 0.9777533287403058 0.8625890542859307 0.8959170139168666 1.0 15.207341523953378 -7.640392432936965 7.476066268796999 0.9097990685164171 0.9873945495938462 0.2274791672138955 0.054994693192278135 0.2821935066515445 17.239115751412168 0.02499197818958022 0.014324941723004333 2.2887985362978488e-08 7.640392432936965 0.07759548107742908 LVAMVFQWFHSTAYMMDDEVGS(ph)LVEK ddPTM_PC-9_AZD4547_30min_R2 1 LVAMVFQWFHSTAYMMDDEVGSLVEK 26 0 G3V2U4;Q9P2D8-2;Q9P2D8;Q9P2D8-3 G3V2U4 UNC79 Protein unc-79 homolog 1 LVAMVFQWFHS(0.22)T(0.22)AY(0.207)MMDDEVGS(0.352)LVEK 42.903999999999996 0.031507 8473300.0 17157.0 10591.0 19074.0 20060.0 17499.0 18197.0 20365.0 17080.0 20494.0 17227.0 True False 22612.569112230634 14014.333631706839 18821.0662972698 15435.476923910517 15069.565904726964 17059.138713364053 22177.445547767446 14440.678459354292 21577.27100066977 16623.88797349071 1.360245518274051 0.8430238253563067 1.1321699428727396 0.928511846839001 0.9065006891743769 1.0261822469308874 1.3340709215036048 0.8686703424843891 1.2979677819700166 1.0 14.02097021677753 -7.041789352342061 24.99339797730654 1.1236464672982795 1.0173869957487967 0.05385141204047661 0.18338260999099573 1401.6193018667882 838277.0041120966 0.06567337321111073 0.05087635122059528 9.082609609471373e-08 7.041789352342061 -0.1062594715494829 LVARPEPATGYTLEFR ddPTM_PC-9_AZD4547_30min_R2 2 LVARPEPATGYTLEFR 16 1 Q16658 Q16658 FSCN1 Fascin 0 ; 100.18 0.0023476 23235000.0 41544.0 53544.0 64243.0 78089.0 67152.0 55340.0 55165.0 60106.0 42385.0 53744.0 False True 54754.127831119054 70851.05089001144 63391.09584436952 60086.78751302328 57829.10392789446 51879.581051688016 60074.578131234535 50817.998798474764 44625.384569307505 51862.438918400425 1.055756901777573 1.3661341882028997 1.2222929959793851 1.1585800584419665 1.1150479062290513 1.000330530797338 1.158344639860747 0.9798613381532448 0.8604567293782772 1.0 15.662402432496263 -6.8802377008075855 0.6786754364340022 0.946550544075051 1.2341077027215737 0.5159191981476803 0.09485285811925462 0.5844834673003771 0.5798924792352111 0.07441226116799296 0.06876236103974877 1.317535419342111e-07 6.8802377008075855 0.28755715864652265 LVARPEPATGYTLEFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LVARPEPATGYTLEFR 16 1 Q16658 Q16658 FSCN1 Fascin 0 ; 67.102 0.033136 18389100.0 49832.0 60576.0 59044.0 62145.0 67073.0 61332.0 69423.0 73374.0 50974.0 38898.0 False True 58267.5733731365 66589.58494716285 60451.832885616976 58663.217126808406 53930.52713755924 58115.64195118466 62846.75086100549 71448.0102461794 51719.39831666638 45949.899483601446 1.2680674828011533 1.4491780329340496 1.3156031583309766 1.2766778118359992 1.17368106880856 1.2647610246008245 1.3677233588603208 1.5549111325407294 1.1255606410003998 1.0 15.487774085140618 -8.514061136097377 23.85821540173551 0.9999999827385291 1.3293720625954428 0.5516024600413145 0.1009113247334643 210.31374525621763 569054.4265440179 0.10257093832654982 0.026483702413277885 3.061532428169909e-09 8.514061136097377 0.32937207985691375 LVARPEPATGYTLEFR ddPTM_PC-9_Lapatinib_30min_R1 2 LVARPEPATGYTLEFR 16 1 Q16658 Q16658 FSCN1 Fascin 0 ; 90.689 0.0044729 21335600.0 71011.0 61400.0 64687.0 63135.0 68154.0 63202.0 55861.0 57375.0 49514.0 52568.0 False True 69998.3701181773 61257.832072404744 59368.684559040994 67778.15851218607 64145.31571591946 60498.99779105793 58753.20925002781 60040.85195773522 43937.21191446505 61654.308757542974 1.1353362243253355 0.993569359658262 0.9629283947130077 1.0993255763960517 1.0404028040955327 0.9812614723971956 0.9529457135117059 0.9738305913678683 0.7126381399757342 1.0 15.911914101524228 -7.51252043473969 1.338050145764666 0.8724405289486533 1.0390448334764597 0.38181251288399065 0.084269267318447 0.46530751425401295 1.5807891363472917 0.05894674473332082 0.027678396968156622 3.0724127964657853e-08 7.51252043473969 0.1666043045278064 LVDVS(ph)PDR ddPTM_PC-9_Lapatinib_30min_R1 2 LVDVSPDR 8 0 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 LVDVS(1)PDR;LVDVS(1)PDR 85.355 0.013288 10348800.0 28047.0 38927.0 36419.0 34305.0 35836.0 32839.0 37452.0 37225.0 35237.0 31896.0 True False 27647.044636810115 38836.86692316775 33424.77040140544 36827.904138125275 33728.1969362868 31434.552521447913 39391.08130595662 38954.60939654368 31268.237997940087 37409.1811012515 0.7390443688671174 1.0381640490352375 0.8934911007791944 0.984461649626787 0.9016021186082162 0.8402897790349195 1.0529789785919375 1.0413114708688578 0.8358439580195468 1.0 15.191104764735323 -7.262439944148977 24.99933851742075 0.9859762211637569 0.9094944611876994 0.15506642719719133 0.09307233157230495 190.92934304811666 4770328.686974592 0.036220528685907916 0.026039838231455368 5.464621114639447e-08 7.262439944148977 -0.07648175997605755 LVDVS(ph)PDRGSPPSR ddPTM_PC-9_AZD4547_30min_R2 1 LVDVSPDRGSPPSR 14 1 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 LVDVS(0.666)PDRGS(0.275)PPS(0.059)R 56.768 0.032867 36192000.0 22512.0 21528.0 28812.0 40424.0 31830.0 25657.0 10078.0 35823.0 25622.0 17041.0 True False 29670.347721311224 28486.504997014894 28429.934054573634 31104.871344574196 27410.953925793423 24052.66373406506 10974.922476327056 30287.37848064691 26976.3266116503 16444.399776876722 1.8042828028927 1.7322921714096957 1.7288520371871743 1.8915175845038918 1.6668868610417336 1.4626659568254168 0.6673957471989603 1.8418050455836934 1.6404567498768206 1.0 14.005308730092686 -6.765934943542548 3.5483972388663365 1.3250415206478845 1.7767055920161372 0.35261914820058116 0.30555916075630185 0.29288570399267805 7.83318946115853 0.11291432949218401 0.10500362118617289 1.714214074166197e-07 6.765934943542548 0.4516640713682527 LVDVS(ph)PDRGSPPSR ddPTM_PC-9_Lapatinib_30min_R1 1 LVDVSPDRGSPPSR 14 1 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 LVDVS(0.996)PDRGS(0.003)PPS(0.001)R 72.428 0.010763 36482000.0 39309.0 43573.0 46608.0 40995.0 39271.0 36992.0 28433.0 23744.0 41414.0 35074.0 True False 38748.446451612246 43472.10939561712 42776.07015208281 44009.909055311036 36961.156989756615 35409.93839256374 29905.121616262528 24847.232921733594 36749.51921124646 41136.49416683269 0.9419481955478388 1.056777206616396 1.0398569693032342 1.0698507480201147 0.8985004127930148 0.8607913510800314 0.7269730253380287 0.6040192151757864 0.8933556433420294 1.0 15.328131225827352 -6.636136674959908 2.033232074551267 0.7782917125138079 1.0292442314430765 0.4551870694827319 0.10517209443087043 0.2514761554172341 2.1263394497110126 0.039413199301439446 0.03944750828126347 2.3113372846300163e-07 6.636136674959908 0.2509525189292686 LVEALCAEHQINLIK ddPTM_PC-9_AZD4547_30min_R2 1 LVEALCAEHQINLIK 15 0 P25398 P25398 RPS12 40S ribosomal protein S12 0 122.39 0.00038365 0.0 8996.9 5790.0 9422.4 10751.0 10996.0 10199.0 7693.7 9010.0 9263.1 9441.4 False True 11857.727052854696 7661.50427037887 9297.452819513213 8272.52305129421 9469.395204776143 9561.254917711709 8378.424395328184 7617.711529202709 9752.72855500655 9110.859459738496 1.3014937948779468 0.8409200366041838 1.0204803246718146 0.9079849258844404 1.0393525711401916 1.04943501323487 0.9196085651801575 0.8361133834701207 1.0704509929172452 1.0 13.153371439657233 -4.748268021591468 24.999321314057116 0.9633128874760944 1.3014946087338302 0.6090630998606973 0.08088430305780353 436.1474700162686 827762.1140122843 0.019642150746392747 0.3647087533376099 1.7853853975413916e-05 4.748268021591468 0.3381817212577357 LVEALCAEHQINLIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LVEALCAEHQINLIK 15 0 P25398 P25398 RPS12 40S ribosomal protein S12 0 98.0 0.0019649999999999997 3067500.0 8503.6 9949.9 12817.0 14657.0 14420.0 13384.0 11781.0 13376.0 10705.0 9960.9 False True 9943.091526244252 10937.660315401721 13122.605888743175 13835.815808635141 11594.504514836124 12682.119478814577 10665.01839294622 13024.894173043502 10861.540373129701 11766.732319558982 0.8450172279109788 0.9295410160066992 1.115229405442531 1.1758418083189395 0.9853631577531023 1.077794508653351 0.9063704436633216 1.1069253399597754 0.9230719351943916 1.0 13.522426111914374 -5.033014097913129 4.64752518645633 1.0399170781920308 0.8594571081530875 0.36728047838114697 0.08156288552866936 0.1837271832995116 9.705697624557626 0.020812569893089963 0.06927379251587369 9.267997374473283e-06 5.033014097913129 -0.18045997003894332 LVEALCAEHQINLIK ddPTM_PC-9_Lapatinib_30min_R1 4 LVEALCAEHQINLIK 15 0 P25398 P25398 RPS12 40S ribosomal protein S12 0 ;;; 139.74 5.3877e-05 9186600.0 53024.5 43127.3 44095.0 43772.3 50788.5 43708.5 46075.9 37273.4 44986.5 44357.0 False True 52268.36090649764 43027.44138658339 40469.679311622305 46991.46096211227 47801.220284032825 41839.189344489976 48461.484650889804 39005.25823723659 39919.646641153675 52024.04834801273 1.0046961466137851 0.8270683030807809 0.7779033081182389 0.9032642105774781 0.9188293068672497 0.8042278652481721 0.931520829111735 0.7497543823639505 0.7673306462832888 1.0 15.666891049194636 -7.753796641275486 24.99975860541337 0.8189068816269572 0.8743777937041718 0.0266499557853509 0.08930957296365881 472.2989276832714 1544925.7566664855 0.041577476251834944 0.02341531442040531 1.7628012862423597e-08 7.753796641275486 0.05547091207721455 LVEDEERR ddPTM_PC-9_AZD4547_30min_R2 2 LVEDEERR 8 1 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ; 101.43 0.0029033 18771600.0 35970.0 32398.0 49394.0 63537.0 46048.0 37893.0 40482.0 49371.0 37400.0 42768.0 False True 47407.71177752153 42870.0199225794 48739.00328653372 48889.52628686455 39655.03004633791 35523.54471976175 44084.81957597455 41741.84638271553 39376.887646386705 41270.705337566076 1.1487012734519304 1.0387518112891947 1.1809588154087043 1.1846060271318783 0.9608517645140046 0.860744792927659 1.0681867250726864 1.0114158709257774 0.9541123013118085 1.0 15.332830474504844 -6.269451201200277 24.9595886773162 0.9753140813761336 1.1341974587131118 0.6222459350987228 0.06194412269749271 422.6048373886637 1316556.9168272128 0.02007628988282558 0.023161686813178636 5.377108487410969e-07 6.269451201200277 0.15888337733697822 LVEDEERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LVEDEERR 8 1 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ; 120.87 0.0021495999999999998 12758300.0 49391.0 52124.0 62724.0 68340.0 62552.0 63919.0 65995.0 66800.0 60442.0 40042.0 False True 57751.92078328352 57298.52624448479 64219.5780420947 64511.13136126933 50295.38463328913 60566.97511703145 59743.475837576174 65046.57078045048 61325.849904970164 47301.297627702384 1.2209373459019155 1.2113521006435868 1.3576705346976357 1.3638342835543662 1.0632982001710083 1.280450603992731 1.2630409488509873 1.3751540452952697 1.296494028296048 1.0 15.5295921414518 -11.784786362265994 2.1654159035499956 2.5526183586741267e-05 1.2709263794631782 0.46055837141133216 0.08774046687370304 1443949.5369771607 237114.77950167615 7074690.454594731 0.022533051747212023 1.6413970091123698e-12 11.784786362265994 1.2709008532795916 LVEDEERR ddPTM_PC-9_Lapatinib_30min_R1 1 LVEDEERR 8 1 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 132.76 0.0025800999999999997 7850800.0 21251.0 23935.0 23105.0 18371.0 18447.0 19820.0 15839.0 19758.0 24441.0 12708.0 False True 20947.956843043892 23879.57997806201 21205.396087879202 19722.064623859475 17361.9837281974 18972.34480267663 16659.065919177796 20676.028810125197 21688.19720486006 14904.560867654387 1.405472930672166 1.6021659537709059 1.4227454452481574 1.3232234615284741 1.164877240085353 1.2729220921798559 1.117715984194543 1.3872283117710598 1.455138289376066 1.0 13.863466249451486 -5.74989506022388 2.63951174338212 1.2488295148197626 1.5044152641792559 0.41162826059385405 0.1305423863602751 0.2723824118749598 3.8689278899688886 0.038061503243344945 0.06927177833117354 1.7787091525260553e-06 5.74989506022388 0.2555857493594933 LVEIDNGK ddPTM_PC-9_Lapatinib_30min_R1 3 LVEIDNGK 8 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ;; 111.74 0.017237 14053900.0 172342.0 137605.0 132276.0 138144.0 143565.0 129352.0 132999.0 116933.0 123355.0 122662.0 False True 169884.37147634817 137286.38407692625 121400.77788012591 148303.57059487456 135120.78895964974 123819.91649423934 139885.03745089498 122366.1340649036 109461.46091426331 143863.96326315854 1.1808681453158123 0.9542791743183074 0.8438581499249915 1.0308597596716769 0.9392260987032893 0.8606736091911059 0.9723424426658868 0.8505683514437127 0.7608678256279819 1.0 17.13434572855447 -4.777388956064695 3.7007740740314947 0.907570142180506 1.2113976171009118 0.5259153786018789 0.07751531846048607 0.21199988748713236 5.0331412329420315 0.019638513175415855 0.17909039583168254 1.6695946481398734e-05 4.777388956064695 0.30382747492040574 LVEPHS(ph)PSPSSK ddPTM_PC-9_AZD4547_30min_R2 3 LVEPHSPSPSSK 12 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 LVEPHS(0.999)PS(0.001)PSSK;LVEPHS(0.974)PS(0.026)PSSK;LVEPHS(0.986)PS(0.013)PS(0.001)SK 89.13600000000001 0.004338600000000001 74958800.0 138988.0 118618.0 207221.0 296894.0 247925.0 219283.0 166572.0 245427.0 178836.0 204919.0 True False 183183.29287000725 156958.94879858397 204473.114144204 228449.67526657484 213504.8932470101 205571.1993450909 181396.58530727823 207501.89650140188 188288.90585906975 197744.84818248954 0.9263618979390851 0.7937448193529363 1.0340249873691034 1.1552749786722596 1.0796988908149776 1.0395780281232854 0.9173264789172952 1.0493416056528968 0.9521810939180911 1.0 17.593280583302302 -5.275698452498845 24.184598132067983 1.0329820908151257 0.8600533675594765 0.48895142549313897 0.06872898051302284 376.206277134795 638078.3258152069 0.018931698336226096 0.039740198621102805 5.300313374682327e-06 5.275698452498845 -0.17292872325564923 LVEPHS(ph)PSPSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LVEPHSPSPSSK 12 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 LVEPHS(0.996)PS(0.003)PS(0.001)S(0.001)K;LVEPHS(0.966)PS(0.022)PS(0.008)S(0.003)K;LVEPHS(0.973)PS(0.015)PS(0.005)S(0.007)K;LVEPHS(1)PSPSSK 84.17299999999999 0.0058671999999999995 53899200.0 159485.0 166590.0 213972.0 232794.0 254866.0 246253.0 243223.0 209982.0 217286.0 180271.0 True False 186482.6605276665 183127.95424504456 219073.9039733291 219751.3069083315 204926.83687088965 233339.0591763691 220183.15665797124 204470.1949943197 220463.39668527467 212952.70527554888 0.8756998897307662 0.8599465971004558 1.02874440449047 1.0319254062726537 0.9623114982536887 1.0957318380832093 1.0339533201659334 0.9601671635481066 1.0352692932452179 1.0 17.70017353192698 -5.260980136776346 24.999914629175343 1.0188713597029286 0.8678232298546961 0.7247604877250684 0.037144568242828455 19.357229643708518 1053679.373531346 0.009663299699248638 0.022554449095772845 5.483020419077497e-06 5.260980136776346 -0.15104812984823257 LVEPHS(ph)PSPSSK ddPTM_PC-9_Lapatinib_30min_R1 3 LVEPHSPSPSSK 12 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 LVEPHS(0.65)PS(0.298)PS(0.021)S(0.032)K;LVEPHS(0.961)PS(0.029)PS(0.008)S(0.003)K;LVEPHS(0.927)PS(0.04)PS(0.013)S(0.02)K 90.229 0.0040019 74091300.0 199809.0 167521.0 207206.0 144856.0 191997.0 192859.0 171129.0 170205.0 204844.0 133850.0 True False 196959.68701951738 167133.1154169592 190170.32251829005 155509.19346545005 180704.11394062554 184610.87014628723 179989.22227937204 178113.34566390113 181772.3116170514 156985.79415608625 1.2546338226227418 1.0646384681838394 1.2113855495052592 0.9905940489802022 1.1510857712447335 1.1759718204994662 1.1465319091255746 1.1345825692152016 1.1578901937860737 1.0 17.2602744881535 -11.123031839384813 2.6411694704843387 0.9877627704889622 1.139315665878905 0.2755241963550138 0.06934612310615237 19827869.73292828 18012468.155917782 1679376.259072392 0.016197819925129243 7.533003350825128e-12 11.123031839384813 0.15155289538994277 LVEQANS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 LVEQANSPK 9 0 O95391 O95391 SLU7 Pre-mRNA-splicing factor SLU7 1 LVEQANS(1)PK;LVEQANS(1)PK;LVEQANS(1)PK 107.09 0.0025256 245483000.0 588391.0 582706.0 534532.0 568474.0 625955.0 549082.0 607561.0 581624.0 569560.0 507965.0 True False 775487.0987069118 771054.3190631071 527443.7564229954 437421.1021357482 539051.9530197934 514747.81573948136 661632.7519983854 491747.3751898997 599665.7788202149 490181.2999625117 1.5820413768665182 1.5729982337597868 1.0760177029669094 0.8923659514738761 1.0996991379740908 1.0501172031222907 1.3497715070913274 1.0031948897836531 1.2233550705954641 1.0 18.902955921991328 -5.2601566185437445 23.588799506127508 1.0885254474472343 1.577519929377685 0.7309201235730068 0.11908926053895548 24.70677119323491 454302.7491917114 0.031086267799041757 0.07344517659886546 5.493427300230943e-06 5.2601566185437445 0.4889944819304506 LVEQANS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LVEQANSPK 9 0 O95391 O95391 SLU7 Pre-mRNA-splicing factor SLU7 1 LVEQANS(1)PK;LVEQANS(1)PK;LVEQANS(1)PK;LVEQANS(1)PK;LVEQANS(1)PK;LVEQANS(1)PK 111.63 0.0022221 233105300.0 1025554.0 1132260.0 760468.0 1128370.0 1072698.0 908269.0 1146209.0 892021.0 780631.0 829145.0 True False 1199160.0365851996 1244663.2899543443 778600.441210949 1065151.0871248993 862510.5273270227 860637.7747238073 1037631.7856854661 868606.3939243741 792046.2515662397 979462.4249917902 1.2243042775175892 1.2707616527145256 0.7949262997173936 1.0874854000997816 0.8805958302425458 0.8786838093671855 1.0593890681351696 0.8868195162582727 0.8086540446642235 1.0 19.901630622041665 -5.248934677017286 24.875767379523616 0.927951269145368 1.2475330240489924 0.656466237798975 0.09342715425464046 412.70187458934134 820989.595898503 0.022999055381556728 0.05994737114471184 5.637224399148346e-06 5.248934677017286 0.3195817549036244 LVEQANS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 LVEQANSPK 9 0 O95391 O95391 SLU7 Pre-mRNA-splicing factor SLU7 1 LVEQANS(1)PK;LVEQANS(1)PK;LVEQANS(1)PK 95.618 0.005368199999999999 260705000.0 359618.0 427541.0 307389.0 271970.0 333986.0 268735.0 327854.0 324011.0 277442.0 248574.0 True False 354489.78137413616 426551.0550825406 282116.66297585395 291971.58106532396 314341.6001217401 257241.83050188224 344828.67591805785 339065.7339203088 246193.56036622 291539.68469596526 1.215922908552978 1.4630977444026982 0.9676784252204355 1.001481432518558 1.0782120466706067 0.8823561388225729 1.1827846911396145 1.1630174268518763 0.8444598567188721 1.0 18.15333275243283 -5.268982501177709 24.976853398438347 1.0238507716503105 1.3395103312707437 0.555070176348143 0.11599855100186388 365.9913658210244 1211876.73069614 0.02962073274165923 0.06358389780779235 5.382914712031658e-06 5.268982501177709 0.31565955962043324 LVES(ph)PKEGK ddPTM_PC-9_AZD4547_30min_R2 1 LVESPKEGK 9 1 Q96S94;Q96S94-3 Q96S94 CCNL2 Cyclin-L2 1 LVES(1)PKEGK 111.94 0.010626 5522200.0 20808.0 18316.0 17709.0 25299.0 27904.0 18081.0 18023.0 17028.0 15920.0 22713.0 True False 27424.511166713008 24236.28881109832 17474.16708914496 19466.706415653636 24030.01125810053 16950.392211701695 19627.01208482264 14396.71386451318 16761.49869867585 21917.824783299144 1.2512423763698406 1.1057798413264892 0.797258270923849 0.8881678089920128 1.0963684350835226 0.7733610602005309 0.8954817496204255 0.6568495736622153 0.7647428001818734 1.0 14.419817005855881 -1.5228787455401391 0.5879054632659457 0.8284164969200779 26.490010634558068 0.5104082485143095 0.12382896491388799 130.68482671932713 1.0560168618370793 0.05884856207503933 4291.844999194664 0.029999999982053542 1.5228787455401391 25.66159413763799 LVETTMVPS(ph)PEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LVETTMVPSPEAK 13 0 Q16236-3;Q16236-2;Q16236;C9J0Y1;K7EIW5;C9J1A8 Q16236-3 NFE2L2 Nuclear factor erythroid 2-related factor 2 1 LVET(0.002)T(0.066)MVPS(0.932)PEAK 94.67299999999999 0.0032658 3322100.0 45632.0 68989.0 47500.0 42718.0 51741.0 29602.0 40469.0 25524.0 33345.0 32229.0 True False 53356.59632691778 75837.77198758289 48632.58014475318 40324.6489536246 41602.722475876304 28049.619008657264 36635.48334981244 24854.02204491344 33832.60754245771 38071.86257537638 1.4014706063114197 1.991963798394047 1.2773890441653128 1.0591719507756694 1.0927419795527307 0.7367545770350314 0.9622718950847197 0.6528186530329672 0.8886512309576238 1.0 15.216437531601635 -5.6903991741564415 1.605738262476752 0.8652817342924414 1.7089034104698073 0.733974709902057 0.1877331354272507 0.18124250325422342 0.9368125852626353 0.056990258964219644 0.1369299395734784 2.0398621792159344e-06 5.6903991741564415 0.8436216761773659 LVEVMFMT(ph)NPAVQPR ddPTM_PC-9_AZD4547_30min_R2 1 LVEVMFMTNPAVQPR 15 0 O95155-2;O95155;O95155-4;O95155-3 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 LVEVMFMT(1)NPAVQPR 58.817 0.045714 0.0 1812.6 1556.5 2314.2 1373.1 2271.3 1851.1 3241.6 3679.3 4299.7 1658.1 True False 2388.9690955778556 2059.608185983541 2283.5121959285825 1056.5530091835262 1955.9692004918193 1735.3504243725995 3530.096120188705 3110.7487269029434 4526.973363988477 1600.050423686362 1.4930586312860699 1.2872145499254968 1.4271501460982652 0.6603248207324179 1.2224422252802851 1.0845598355422572 2.206240545879613 1.9441566845975256 2.8292691886289227 1.0 10.64390165530972 -7.2602680112039915 24.99999863814291 2.0735963558205937 1.1873355426634027 0.40567141152350006 0.46994562334572054 95.27488913131471 2033439.7797260673 0.17798532221400526 0.13002296258422988 5.4920184658200065e-08 7.2602680112039915 -0.886260813157191 LVGATATSS(ph)PPPK ddPTM_PC-9_AZD4547_30min_R2 2 LVGATATSSPPPK 13 0 H9KVD1;Q96QD9-4;Q96QD9 H9KVD1 FYTTD1 UAP56-interacting factor 1 LVGAT(0.001)AT(0.025)S(0.052)S(0.923)PPPK;LVGATAT(0.003)S(0.027)S(0.971)PPPK 169.09 0.00025827 118167000.0 78683.0 77509.0 100680.0 124411.0 99863.0 86842.0 72098.0 93806.0 91487.0 100728.0 True False 103702.55729193 102562.26847889388 99344.91741685674 95729.96608078927 85998.74621085475 81411.756011758 78514.5823276668 79310.43814743508 96322.81604558788 97201.54337921708 1.0668817972092295 1.055150617092187 1.0220508230952425 0.9848605562497431 0.8847467151354138 0.8375562072522077 0.8077503668985384 0.8159380539670799 0.9909597388777976 1.0 16.56869160086883 -6.050139280980882 1.9502083172658693 0.8718285258164546 1.0535014295640677 0.558437603738029 0.06314343567604326 0.2282613230975256 1.73115450840033 0.02067715210956862 0.031772859554617935 8.909651541626218e-07 6.050139280980882 0.18167290374761302 LVGATATSS(ph)PPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LVGATATSSPPPK 13 0 H9KVD1;Q96QD9-4;Q96QD9 H9KVD1 FYTTD1 UAP56-interacting factor 1 LVGATAT(0.002)S(0.015)S(0.982)PPPK;LVGAT(0.002)AT(0.108)S(0.108)S(0.782)PPPK;LVGAT(0.019)AT(0.016)S(0.045)S(0.92)PPPK;LVGATAT(0.009)S(0.075)S(0.916)PPPK;LVGAT(0.006)AT(0.025)S(0.052)S(0.918)PPPK;LVGAT(0.002)AT(0.052)S(0.355)S(0.591)PPPK 149.23 0.00012043 156344600.0 236804.0 222482.0 242691.0 267506.0 295451.0 251131.0 274905.0 258649.0 251897.0 192893.0 True False 276890.2401078068 244568.5426276858 248477.6738507434 252518.50608615312 237559.49746275018 237961.24826914098 248864.00826015446 251859.7378112688 255580.51708269503 227862.97395985195 1.2151611790891186 1.073314099160214 1.0904697219238595 1.1082033280696377 1.0425541865551473 1.0443173111181647 1.0921651900497127 1.1053122560212214 1.1216412769532567 1.0 17.797806990860003 -4.7600757436433465 24.933847916232452 1.078654808036069 1.2151613504046497 0.5842553577701854 0.035286138602743246 24.43568889575071 446632.3114987166 0.008691763297694338 0.05289878252784777 1.7374977719664358e-05 4.7600757436433465 0.13650654236858073 LVGATATSS(ph)PPPK ddPTM_PC-9_Lapatinib_30min_R1 2 LVGATATSSPPPK 13 0 H9KVD1;Q96QD9-4;Q96QD9 H9KVD1 FYTTD1 UAP56-interacting factor 1 LVGATAT(0.006)S(0.065)S(0.929)PPPK;LVGATAT(0.004)S(0.027)S(0.969)PPPK 196.5 9.7988e-07 143400000.0 607470.0 629690.0 657810.0 519200.0 611790.0 567090.0 573250.0 577560.0 561240.0 455380.0 True False 598807.3664036467 628231.9914930371 603727.4010200318 557383.7000004258 575805.7150254186 542836.8826513566 602930.0800662086 604395.5460864414 498027.24108079326 534091.826244291 1.12116931392572 1.1762621343800286 1.1303812778139948 1.043610241931471 1.0781024661516685 1.0163736945172153 1.1288884241235912 1.131632270683719 0.9324749352239627 1.0 19.026728279792003 -1.522878745609763 0.13080905392286693 0.9717164549463727 1.58732699315389 0.3799928500927825 0.05674038416149928 95.79408528068778 0.85014024563826 0.3087116193928755 10.882988225577224 0.029999999977244098 1.522878745609763 0.6156105382075173 LVGIISS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 LVGIISSR 8 0 P12268;H0Y4R1;E7ETK5 P12268 IMPDH2 Inosine-5-monophosphate dehydrogenase 2 1 LVGIIS(0.191)S(0.809)R 68.846 0.042481 5705400.0 48675.0 49622.0 50214.0 40779.0 46689.0 50030.0 40314.0 47440.0 47333.0 37172.0 True False 47980.88557409825 49507.10330776658 46085.59875164539 43778.02369475618 43942.84481410575 47890.33352562621 42401.261662083045 49644.23558823458 42001.85910141321 43597.13067142344 1.1005514545375397 1.1355587522693769 1.0570787123349168 1.0041491956132633 1.007929745314843 1.0984744360026617 0.9725700065365942 1.1387041950624248 0.9634087944449088 1.0 15.411945567250571 -5.413155427051065 4.39125112262091 1.0320801016203962 1.1171191238643368 0.32143141960855415 0.05207470057919801 0.25503755574509956 8.01260410411071 0.0129392546370108 0.028164571121852028 3.862287272308446e-06 5.413155427051065 0.08503902224394055 LVGS(ph)PPWK ddPTM_PC-9_AZD4547_30min_R2 2 LVGSPPWK 8 0 Q86UA6-6;Q86UA6-5;Q86UA6-7;Q86UA6-3;Q86UA6-4;Q86UA6-9;Q86UA6-2;Q86UA6;Q86UA6-8 Q86UA6-6 RPAIN RPA-interacting protein 1 LVGS(1)PPWK;LVGS(1)PPWK 89.88600000000001 0.009889299999999998 12442600.0 160132.0 146442.0 189561.0 270660.0 231816.0 179134.0 178002.0 209873.0 185162.0 205753.0 True False 211050.6450474859 193776.51267060838 187047.29728304292 208263.51865531522 199632.3498354299 167932.72266196404 193843.8331644346 177441.95025176037 194949.28530428506 198549.65009633882 1.0629615561905117 0.9759599806727715 0.9420681285123654 1.0489241283188517 1.005453042795924 0.8457971221831967 0.9762990419292056 0.8936905714296816 0.9818666777286849 1.0 17.599140292842776 -6.626135847171364 21.054075247038604 0.9341139105768643 1.0041075460219329 0.286302481228641 0.052869241067309024 4.713552724598315 946.0090215602537 0.01675658897383801 0.016756568354457758 2.3651797543141216e-07 6.626135847171364 0.06999363544506854 LVGS(ph)PPWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LVGSPPWK 8 0 Q86UA6-6;Q86UA6-5;Q86UA6-7;Q86UA6-3;Q86UA6-4;Q86UA6-9;Q86UA6-2;Q86UA6;Q86UA6-8 Q86UA6-6 RPAIN RPA-interacting protein 1 LVGS(1)PPWK 70.55199999999999 0.037828 5227600.0 116990.0 81189.0 107840.0 129580.0 133960.0 124350.0 115660.0 110210.0 114070.0 106030.0 True False 136794.09634217483 89248.9073605914 110411.31458547771 122320.05270402803 107711.49963990612 117828.8670943358 104703.84749411397 107317.10427714759 115738.05795076171 125252.39966698176 1.0921475093960664 0.7125524748259066 0.8815105728835281 0.9765884967413783 0.8599555771089976 0.9407314143889979 0.8359428463845658 0.856806772265281 0.9240386472313779 1.0 16.93447871821251 -8.567077611142917 7.668524138408829 0.9999992958084706 0.8892441127958267 0.10211516197899906 0.0935312039227147 1.6940918337221684 292.40155015671485 0.0847454769675513 0.021910727561216762 2.7097073469521076e-09 8.567077611142917 -0.11075518301264387 LVGS(ph)PPWK ddPTM_PC-9_Lapatinib_30min_R1 1 LVGSPPWK 8 0 Q86UA6-6;Q86UA6-5;Q86UA6-7;Q86UA6-3;Q86UA6-4;Q86UA6-9;Q86UA6-2;Q86UA6;Q86UA6-8 Q86UA6-6 RPAIN RPA-interacting protein 1 LVGS(1)PPWK 83.78299999999999 0.014566999999999998 4313300.0 53561.0 44835.0 42107.0 42339.0 44040.0 42845.0 38582.0 40385.0 51028.0 39591.0 True False 52797.21031811559 44731.18731215421 38645.124997720384 45452.751298763615 41449.65378597136 41012.61922657316 40579.587176824134 42261.43453269087 45280.68929133825 46434.25159830853 1.1370315769241093 0.9633231025044374 0.8322547186079363 0.9788625795450384 0.8926525648467919 0.8832406642700608 0.8739149610478988 0.9101349344075643 0.9751570819542981 1.0 15.50290176209043 -4.8002084430637355 3.6282338933523635 0.9126380665857903 1.1575041948014373 0.6256186675639989 0.050391418984848294 0.15223934591355773 3.4246730789251396 0.012124275028874223 0.0983105641681241 1.5841326929849928e-05 4.8002084430637355 0.24486612821564702 LVGS(ph)QEELASWGHEYVR ddPTM_PC-9_AZD4547_30min_R2 2 LVGSQEELASWGHEYVR 17 0 Q13200;Q13200-3;H7C2Q3 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 1 LVGS(1)QEELASWGHEYVR;LVGS(1)QEELASWGHEYVR 126.62 2.0419000000000002e-05 14205300.0 9447.3 9976.5 33967.0 56925.0 46226.0 42595.0 37496.0 57952.0 33491.0 46480.0 True False 12451.344883952714 13201.208523909285 33516.57538635648 43801.82073248287 39808.31781884153 39931.52791645557 40833.07136062307 48996.85000447895 35261.26588676837 44852.74934741092 0.2776049420629653 0.2943232848817842 0.7472579914054074 0.9765693601792838 0.8875335045908268 0.8902804955647735 0.9103805665143717 1.0923934589821802 0.7861561754809974 1.0 15.452908800553656 -5.35877388247905 2.7338518637987037 0.9330115463197585 0.26324482621712386 0.9158305384167628 0.07754154880499256 0.06637041591228843 0.9471700631902792 0.020548223787121303 0.05512304690010643 4.377499624692066e-06 5.35877388247905 -0.6697667201026346 down LVGS(ph)QEELASWGHEYVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LVGSQEELASWGHEYVR 17 0 Q13200;Q13200-3;H7C2Q3 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 1 LVGS(1)QEELASWGHEYVR 161.97 1.7383e-05 4375100.0 5443.0 6436.5 12008.0 11902.0 18821.0 14203.0 16216.0 14195.0 13335.0 10024.0 True False 6364.392395849696 7075.473182653409 12294.316260593603 11235.169526804626 15133.160157678967 13458.16967704747 14679.90308632678 13822.39629084573 13529.999147658536 11841.271850059657 0.5374754060576383 0.5975264542733864 1.0382597761685257 0.9488144237435122 1.278001244233129 1.1365476485517616 1.2397235087760292 1.1673067273407876 1.1426136752016527 1.0 13.531536426160658 -5.2724740414342754 1.3071413504202007 1.1637255970925042 0.44362233094183845 0.8500632361246541 0.09333295913036274 0.21459096600525127 0.559171924697575 0.027558299123745418 0.16280299626669348 5.33981189640654e-06 5.2724740414342754 -0.7201032661506658 LVGS(ph)QEELASWGHEYVR ddPTM_PC-9_Lapatinib_30min_R1 1 LVGSQEELASWGHEYVR 17 0 Q13200;Q13200-3;H7C2Q3 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 1 LVGS(1)QEELASWGHEYVR 121.14 4.3026000000000004e-05 4013100.0 9622.7 7259.1 11684.0 11580.0 11087.0 10276.0 9528.5 8902.6 12272.0 9587.7 True False 9485.47853341294 7242.291999947778 10723.386621544287 12431.631829747581 10434.884457880671 9836.519434525982 10021.839106691436 9316.247296539148 10889.798130110983 11244.921170192785 0.8435344623452188 0.6440500462684537 0.9536204353276443 1.1055330350114363 0.9279642160178677 0.8747521912914702 0.8912324910962109 0.8284848915823416 0.9684192503702795 1.0 13.45698592703507 -5.27787902293283 24.59799181425013 0.9384995237640531 0.7437922553263714 0.4723542277022986 0.08438925795730329 521.6654126596419 780547.418572189 0.02317674861588899 0.04848006896632282 5.27376747025794e-06 5.27787902293283 -0.1947072684376817 LVGYLDR ddPTM_PC-9_Lapatinib_30min_R1 1 LVGYLDR 7 0 C9JIZ6;P07602;P07602-2;P07602-3;Q5BJH1 C9JIZ6 PSAP Prosaposin;Saposin-A;Saposin-B-Val;Saposin-B;Saposin-C;Saposin-D 0 114.59 0.039616000000000005 8191600.0 45359.0 47788.0 43994.0 38251.0 46873.0 49744.0 38049.0 38630.0 44308.0 34471.0 False True 44712.17234217813 47677.34982208595 40376.98314175104 41064.10614159538 44116.022295863644 47616.56507892762 40018.99104481318 40424.89082574835 39317.566456075416 40429.266420279695 1.1059357812079935 1.1792781329856272 0.9987067962602847 1.0157024793553326 1.0911902738293227 1.1777746492833396 0.9898520202864547 0.9998917716070863 0.9725025937238713 1.0 15.303112406027568 -7.30972097187345 23.725874925274844 0.9905524338995415 1.090483730808201 0.46164914283487835 0.05501038602662787 235.1642276631927 115559.9143557245 0.024859884373454766 0.016760594000539135 4.900935965144265e-08 7.30972097187345 0.09993129690865943 LVHDS(ph)LEDLQMTR ddPTM_PC-9_AZD4547_30min_R2 2 LVHDSLEDLQMTR 13 0 A0A087WYY3;A0A2R8Y635;A0A2R8YDN7;Q9H7F0-2;Q9H7F0 A0A087WYY3 ATP13A3 Probable cation-transporting ATPase 13A3 1 LVHDS(1)LEDLQMTR;LVHDS(1)LEDLQMTR 98.421 0.001916 13694800.0 26994.1 33107.0 40521.0 42164.0 40423.0 36034.0 42444.0 43209.0 34488.0 34833.0 True False 35577.662287839674 43808.19030732871 39983.66506404895 32443.741227306233 34810.96420177024 33780.788283637994 46221.43377507693 36532.041894042144 36310.965271352536 33613.50727234006 1.058433504114457 1.3032912618249055 1.189511845345302 0.9651995242401734 1.0356242780537082 1.004976600922439 1.375085122792637 1.086826245117947 1.0802492277035358 1.0 15.036753462523352 -5.567519762029758 24.992477278764802 1.0885040077608077 1.1972477085943967 0.1320465262176015 0.12063347747682247 255.6650112543834 143134.06789127292 0.033750662347537486 0.05845790367206616 2.706950024727749e-06 5.567519762029758 0.10874370083358897 LVHDS(ph)LEDLQMTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LVHDSLEDLQMTR 13 0 A0A087WYY3;A0A2R8Y635;A0A2R8YDN7;Q9H7F0-2;Q9H7F0 A0A087WYY3 ATP13A3 Probable cation-transporting ATPase 13A3 1 LVHDS(1)LEDLQMTR;LVHDS(1)LEDLQMTR 66.738 0.025481 9369800.0 28230.0 27588.0 30757.0 30133.0 50792.0 32432.0 31230.0 28727.0 30960.0 27098.0 True False 33008.781432084696 30326.754317259732 31490.363526572037 28444.745702504115 40839.67221342279 30731.208826726983 28271.668314379982 27972.94668877245 31412.731429434418 32010.652892350026 1.0311811365763552 0.9473956816578173 0.9837463682003709 0.8886024848715879 1.275815034162666 0.9600306788516392 0.8831956164548086 0.8738636722857185 0.9813211725194615 1.0 14.966264482079609 -10.007803661653636 5.652376026114254 0.9999999958435762 0.9790619534620179 0.0026391633770087575 0.10982292044023535 42606028.33427911 37718010.07397676 0.11426786172573858 0.027444302832245766 9.821918776153366e-11 10.007803661653636 -0.020938042381558386 LVHDS(ph)LEDLQMTR ddPTM_PC-9_Lapatinib_30min_R1 5 LVHDSLEDLQMTR 13 0 A0A087WYY3;A0A2R8Y635;A0A2R8YDN7;Q9H7F0-2;Q9H7F0 A0A087WYY3 ATP13A3 Probable cation-transporting ATPase 13A3 1 LVHDS(1)LEDLQMTR;LVHDS(1)LEDLQMTR;LVHDS(1)LEDLQMTR;LVHDS(1)LEDLQMTR;LVHDS(1)LEDLQMTR 139.0 3.7708e-05 20522300.0 108036.0 125717.0 83443.0 62822.4 73608.5 67453.2 53209.3 45117.600000000006 90430.0 41375.7 True False 106495.38682862392 125425.91001052948 76582.6386392946 67442.5688653828 69278.99274987902 64568.3838770891 55964.21719889558 47213.92840589659 80244.821129884 48527.434615345264 2.1945398035722277 2.5846392047039615 1.578130788209393 1.3897822829492046 1.4276252865831842 1.330554239862319 1.1532490361894934 0.9729327086861229 1.6535970171501528 1.0 15.566512974134449 -5.416574784526868 3.257005719340176 1.2829994658051374 2.3915101459283563 0.8061284183497688 0.2145587215880396 0.0982253842159204 1.9396831683975828 0.057677474711878125 0.13445468716665807 3.83199748588946e-06 5.416574784526868 1.108510680123219 LVHILNMVTGTIHTYPVT(ph)EDES(ph)LQS(ph)LK ddPTM_PC-9_Lapatinib_30min_R1 1 LVHILNMVTGTIHTYPVTEDESLQSLK 27 0 A0A499FJS7;O14920-4;O14920-2;O14920;E5RGW5;G3V105 A0A499FJS7 IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta 3 LVHILNMVT(0.131)GT(0.131)IHT(0.131)Y(0.121)PVT(0.555)EDES(0.946)LQS(0.986)LK 51.645 0.027267000000000003 0.0 4447.2 6425.4 6897.6 7083.9 7866.7 6687.6 7209.6 6176.7 7377.4 5897.7 True False 4383.7821124834045 6410.5223810754 6330.505953505977 7604.873637197654 7403.996172527269 6401.5869375570255 7582.877811156277 6463.692031151951 6546.479524533962 6917.109586808721 0.6337592396748346 0.9267631661208015 0.915195266759771 1.0994293991959494 1.0703887338502003 0.92547137749056 1.0962494833994259 0.9344498522155178 0.9464183619439007 1.0 12.755953597683083 -4.35761325118143 1.3831492265521896 1.0060744967837691 0.002438137323043628 0.7358727344439798 0.06563385502116117 1.8133684670269035 1.4232642454655922 0.01902177756255579 3.3826608136206007 4.389213929727865e-05 4.35761325118143 -1.0036363594607256 LVHNLTS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 LVHNLTSPK 9 0 Q7Z7G8-2;Q7Z7G8-6;Q7Z7G8 Q7Z7G8-2 VPS13B Vacuolar protein sorting-associated protein 13B 1 LVHNLT(0.384)S(0.616)PK 67.749 0.025453 5032300.0 34214.0 40854.0 38138.0 39432.0 40481.0 39442.0 35289.0 41708.0 35311.0 35711.0 True False 45093.34030459051 54059.25655648675 37632.26520107349 30341.56161832697 34860.911902923144 36975.685504891204 38429.65263614856 35262.98695449349 37177.46737116475 34460.76875958245 1.3085413334562213 1.5687188214991457 1.0920320862142447 0.8804667658463059 1.011611555915433 1.0729791248377023 1.1151710777044836 1.0232791729200172 1.078834532988382 1.0 15.072667265478714 -5.359225451191238 5.6409246268470135 1.0295449040252902 1.4358489525990878 0.789431156567632 0.08389470067546806 0.0867801625361525 4.002751046099663 0.02191621990411811 0.0467805612163796 4.372950373843216e-06 5.359225451191238 0.40630404857379765 LVHS(ph)GSGCRSPSLGSDLTFATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LVHSGSGCRSPSLGSDLTFATR 22 1 Q13425 Q13425 SNTB2 Beta-2-syntrophin 1 LVHS(0.373)GS(0.298)GCRS(0.26)PS(0.066)LGS(0.002)DLTFATR 49.326 0.018009 7104400.0 47788.0 39205.0 47374.0 59240.0 84519.0 67535.0 69484.0 69156.0 72995.0 48852.0 True False 55877.564543976696 43097.013303181375 48503.5758268955 55920.974858671354 67958.10867471801 63993.345711427304 62901.97249940373 67340.72827683888 74062.41378202726 57708.48088778079 0.9682730109052 0.7468055412338319 0.8404930277269812 0.9690252454819354 1.1776104244862817 1.108907126421643 1.089995292402899 1.1669121633575634 1.2833887262783459 1.0 15.816495733699965 -6.036311787740766 2.9414349170749876 1.1422511184161335 0.8423493182623742 0.6990712532938828 0.08477864742669289 0.13799179116494728 2.395607822975248 0.025574698489490545 0.03695756819095377 9.197890017637138e-07 6.036311787740766 -0.2999018001537592 LVHSGS(ph)GCRSPSLGSDLTFATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LVHSGSGCRSPSLGSDLTFATR 22 1 Q13425 Q13425 SNTB2 Beta-2-syntrophin 1 LVHS(0.298)GS(0.391)GCRS(0.308)PS(0.003)LGSDLTFATR 67.832 0.0010162 3963200.0 8562.7 9956.7 12049.0 14108.0 15787.0 16679.0 13258.0 12791.0 13096.0 8123.8 True False 10012.195988966043 10945.135374462083 12336.293856086962 13317.574498753129 12693.65067792774 15804.323878298579 12002.106260392235 12455.249803184755 13287.504224802104 9596.58063203458 1.0433086922173183 1.1405245049393802 1.2854884806476672 1.3877416352130059 1.322726413151238 1.6468703264516718 1.2506648691438813 1.2978841402746706 1.384608198929394 1.0 13.228304733833138 -5.188724026676521 2.036835854198737 1.34979887557002 1.0430787428375663 0.27547270902559395 0.15080651272468873 0.45160579876808293 3.281132744649483 0.04060352187772218 0.18584757170834 6.475539745428862e-06 5.188724026676521 -0.3067201327324538 LVHSGSGCRS(ph)PSLGSDLTFATR ddPTM_PC-9_AZD4547_30min_R2 1 LVHSGSGCRSPSLGSDLTFATR 22 1 Q13425 Q13425 SNTB2 Beta-2-syntrophin 1 LVHS(0.021)GS(0.008)GCRS(0.489)PS(0.443)LGS(0.035)DLT(0.004)FAT(0.001)R 45.14 0.031662 9730400.0 2123.3 1906.9 9746.6 17595.0 9025.2 6986.7 5380.3 10101.0 5531.7 7180.7 True False 2798.4652326163864 2523.2681335380753 9617.353715684696 13538.744590040154 7772.206766291889 6549.820544521659 5859.136276977819 8540.122547888624 5824.0943688106245 6929.305878634974 0.4038593881740526 0.3641444291437661 1.3879245459978524 1.9538384979921244 1.1216429036934015 0.9452347261385334 0.845558902954942 1.2324643618663533 0.840501844025672 1.0 12.758495126836157 -5.253058833014395 24.7145532540707 1.1814370281470579 0.38400176036939326 0.5031619074834234 0.31047879419386765 458.72002112363214 1352773.6764351737 0.08733791049809914 0.22286172304325383 5.583945450084233e-06 5.253058833014395 -0.7974352677776646 LVHSGSGCRS(ph)PSLGSDLTFATR ddPTM_PC-9_Lapatinib_30min_R1 2 LVHSGSGCRSPSLGSDLTFATR 22 1 Q13425 Q13425 SNTB2 Beta-2-syntrophin 1 LVHS(0.057)GS(0.057)GCRS(0.884)PSLGSDLTFATR;LVHS(0.022)GS(0.022)GCRS(0.867)PS(0.075)LGS(0.011)DLT(0.002)FATR 77.469 0.00030514 8311900.0 72822.3 62110.2 63292.7 38852.9 49878.5 52133.1 31425.7 39171.1 80900.4 27547.3 True False 71783.84064802586 61966.38764793933 58089.018522887374 41710.271875474944 46944.744694903995 49903.48884119176 33052.768978868946 40991.13230713101 71788.54503302074 32308.81410053002 2.221803636143001 1.917940641681515 1.7979310024237143 1.2909873988470129 1.4530011701708938 1.5445781663763727 1.0230263752802589 1.2687290898262513 2.2219492430037246 1.0 14.979640176804438 -5.3343383947311835 1.5398677845232434 1.401224872363802 2.194375285334023 0.410657833441331 0.3283839067275066 0.49947747905459416 2.0260618278994698 0.09790134451563844 0.43258911763922325 4.630859505796614e-06 5.3343383947311835 0.7931504129702209 LVIEEAER ddPTM_PC-9_Lapatinib_30min_R1 1 LVIEEAER 8 0 P50991;P50991-2 P50991 CCT4 T-complex protein 1 subunit delta 0 101.6 0.020899 2464400.0 11689.0 13177.0 13525.0 10420.0 13330.0 15493.0 13018.0 12909.0 15968.0 16898.0 False True 11522.31271649993 13146.48946609246 12413.026708009786 11186.32156010102 12545.955607788343 14830.400505946965 13692.008342436793 13508.799266621429 14169.515689505552 19818.796784830334 0.5813830598091261 0.663334389510216 0.6263259491873362 0.5644299036691891 0.6330331626080976 0.748299741248592 0.690859717221426 0.6816155094219094 0.7149533770057703 1.0 14.274581757550619 -14.522878742805828 0.1690417893514149 2.3614995163540895 0.5731890706728797 0.8801241020446573 0.04034251105137385 45.246978450691536 0.4244381606167006 20.552989136655587 0.15978279146934493 3.0000000170933073e-15 14.522878742805828 -1.7883104456812098 LVIGDHK ddPTM_PC-9_AZD4547_30min_R2 1 LVIGDHK 7 0 E9PM92;O00193;E9PRZ9 E9PM92 C11orf58;SMAP Small acidic protein 0 120.49 0.0050638 2619700.0 23568.0 24794.0 31676.0 43583.0 29183.0 34720.0 24519.0 34947.0 28407.0 30989.0 False True 31062.133755146682 32808.1756269039 31255.95554326928 33535.61270063771 25131.444185247536 32548.952911359032 26701.143500403155 29546.744152169464 29908.536025960086 29904.084542317512 1.038725452745106 1.0971135257619 1.045206901386288 1.1214392018314818 0.8404017233727328 1.0884450538955222 0.8928928575833228 0.9880504487725624 1.000148858716483 1.0 14.868054932417236 -6.224097445162063 24.99988541645727 0.9699601625016506 1.074983978487204 0.3869192582760258 0.06614651974609236 584.5000703183482 391314.1820138359 0.01808717348825053 0.023349899446439618 5.969013413547785e-07 6.224097445162063 0.10502381598555333 LVIGDHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LVIGDHK 7 0 E9PM92;O00193;E9PRZ9 E9PM92 C11orf58;SMAP Small acidic protein 0 ; 124.59 0.0038868 3749700.0 41300.0 44856.0 48140.0 49179.0 58010.0 51528.0 50203.0 50040.0 48228.0 38022.0 False True 48291.27428781782 49309.007237023456 49287.84017196669 46423.66007046923 46643.356928269335 48825.78097014025 45447.40840175531 48726.503021762604 48933.24326158798 44915.0876180136 1.0751682084763465 1.0978272525343498 1.0973559840546623 1.0335872093868657 1.0384785915359676 1.0870685900779193 1.0118517142450865 1.0848582426503028 1.0894611556309837 1.0 15.454912527753804 -5.7498549691654075 24.997583793806207 1.0524239015087542 1.0908881691548966 0.27777337779705624 0.029840848058314887 307.5979489598492 663748.4599317492 0.007961969748395357 0.013637737470972439 1.7788733582140153e-06 5.7498549691654075 0.038464267646142414 LVIGDHK ddPTM_PC-9_Lapatinib_30min_R1 2 LVIGDHK 7 0 E9PM92;O00193;E9PRZ9 E9PM92 C11orf58;SMAP Small acidic protein 0 ; 124.59 0.0038868 9175800.0 108445.0 96900.0 98944.0 105972.0 114047.0 99679.0 96244.0 91335.0 99550.0 102550.0 False True 106898.55441362249 96675.63400351812 90809.20625488514 113765.53439222861 107338.97968502901 95415.96153309807 101227.04339449121 95578.75753481043 88337.63069202643 120275.6308607145 0.8887798272071974 0.8037840526105706 0.7550091868572028 0.9458735204970579 0.8924416269271802 0.7933108381995915 0.8416255451756262 0.7946643626047212 0.7344599239252882 1.0 16.875984840992572 -6.774423492522206 24.9874831568298 0.8205295044263521 0.8534628633294025 0.01007420331318154 0.08058536677314329 964.6027412388746 1856333.4240341012 0.028118402767173197 0.024946978809109205 1.6810340389498527e-07 6.774423492522206 0.03293335890305038 LVIIEGDLER ddPTM_PC-9_Lapatinib_30min_R1 2 LVIIEGDLER 10 0 A0A087WWU8;P06753-5;P06753-2;P06753-4;P06753-3;P06753-6;P06753-7;J3KN67;A0A494C0P6;A0A2R2Y2Q3;P06753 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 ; 103.7 0.012575 4992700.0 22233.6 22166.1 26901.0 20276.4 31702.0 30423.0 29864.0 31184.0 36181.0 28415.0 False True 21916.544786857114 22114.77575733113 24689.303620862942 21767.59409608754 29837.350688530067 29121.87920947685 31410.21179432577 32632.922482788934 32105.914777179398 33326.494889392474 0.6576312588406336 0.6635794082374401 0.7408310925827765 0.6531618211975834 0.8953041952823857 0.8738356465667827 0.942499710772865 0.979188558265565 0.963375082910337 1.0 15.024381969676686 -6.491103358185455 1.033083238913328 0.9763012390502264 0.662131916219878 0.9113052100023039 0.040390843878751484 0.13600075901943945 0.31076520267829166 0.01920408324585369 0.02306047118247696 3.227725860536265e-07 6.491103358185455 -0.3141693228303484 LVIIESDLER ddPTM_PC-9_Lapatinib_30min_R1 2 LVIIESDLER 10 0 P09493-3;P09493-4;P09493-10;P09493-9;P09493;P09493-8;Q6ZN40;H0YKX5;A0A0S2Z4G6;H7BYY1;P09493-2;B7Z596;F5H7S3;P09493-7;A0A494BZZ2;H0YK48;P09493-5;P09493-6;H0YKJ4;H0YL42;A0A494C0V8 P09493-3 TPM1 Tropomyosin alpha-1 chain 0 ; 131.11 0.0008793 4327800.0 21635.5 18638.7 18476.2 15955.900000000001 19895.1 21872.0 16020.2 18550.1 21027.5 18218.2 False True 21326.973802535238 18595.543235308305 16957.158156194502 17129.350113322056 18724.909333271535 20936.585546122267 16849.647568559372 19412.005366469446 18659.1615206086 21367.191595774402 0.9981177782274804 0.8702848547951327 0.7936072497027624 0.8016659576689327 0.8763392816197049 0.9798473258536563 0.788575676547571 0.9084958722562484 0.8732622364980643 1.0 14.38310967888532 -6.527755570686519 24.984658971242993 0.9002111877055052 0.8583077976344596 0.0627069972638793 0.07526076692947976 433.63960431654084 2221574.180210716 0.025126550210902213 0.025220048657334095 2.9665005234987165e-07 6.527755570686519 -0.0419033900710456 LVILANNCPALR ddPTM_PC-9_Lapatinib_30min_R1 1 LVILANNCPALR 12 0 P62888;E5RI99;E5RJH3 P62888 RPL30 60S ribosomal protein L30 0 87.696 0.038877999999999996 3176000.0 12183.0 13215.0 13196.0 10937.0 13053.0 14768.0 15093.0 10129.0 14509.0 12864.0 False True 12009.26818591142 13184.40147942718 12111.075818033069 11741.343464762453 12285.248203185376 14136.40706588942 15874.441689383826 10599.630317732468 12874.84363345667 15087.525259797447 0.795973360714867 0.8738611039517944 0.80272116264849 0.7782153310489359 0.8142652947810414 0.9369599601306122 1.0521567597095074 0.7025426725200903 0.8533436340128797 1.0 13.881068565916921 -6.74420005302804 24.068443153109328 0.8993567724405217 0.8138836401616264 0.2177808008139911 0.09003274249333695 297.4067045725687 415218.47708276537 0.030990586724817425 0.0309082683711454 1.8021873916141186e-07 6.74420005302804 -0.0854731322788953 LVINGNPIT(ph)IFQERDPSK ddPTM_PC-9_AZD4547_30min_R2 1 LVINGNPITIFQERDPSK 18 1 P04406;P04406-2 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 LVINGNPIT(1)IFQERDPSK 75.764 0.0041006 4816100.0 9448.8 11599.0 13226.0 13812.0 17999.0 13583.0 12142.0 12966.0 8959.0 12936.0 True False 12453.321852750769 15348.149919192483 13050.614598285123 10627.85679327278 15500.149535355193 12733.652862758914 13222.614477829238 10962.402629039107 9432.554449839006 12483.11457741196 0.9976133580705011 1.2295128610743322 1.0454614124827508 0.8513786144768514 1.2416892786839047 1.020070174297711 1.0592400154489805 0.8781784835072681 0.7556250798904863 1.0 13.607690315735427 -7.772538533970124 5.046710853591604 0.8588866960455834 1.067116849854568 0.33588934960125016 0.11896354903287838 0.19230174691506519 13.39647571189821 0.06309488268342234 0.03153220737985599 1.688346049702633e-08 7.772538533970124 0.20823015380898457 LVINGNPITIFQER ddPTM_PC-9_AZD4547_30min_R2 3 LVINGNPITIFQER 14 0 P04406;P04406-2 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ;; 171.32 0.00049663 8770720.0 16596.82 17944.2 18435.0 23896.5 28251.9 19395.399999999998 16956.8 25987.6 24226.47 19555.5 False True 21874.263524698483 23744.31173204362 18190.539854784973 18387.531122244654 24329.61134829166 18182.602571917414 18465.922350325705 21971.813555639095 25507.03174488124 18870.867897230954 1.159155140284154 1.258252236269842 0.9639482377731122 0.9743871464938175 1.2892682774734332 0.9635276273957419 0.9785412335505422 1.1643244855136294 1.3516618251895056 1.0 14.203873155547559 -7.987167017025984 24.520804163854304 1.2032183460264292 1.0840531581194792 0.0714699431339636 0.1391197434631958 374.4582135948802 715501.0390970459 0.07613318063495958 0.03653680871596732 1.0299899400937916e-08 7.987167017025984 -0.11916518790694997 LVINGNPITIFQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LVINGNPITIFQER 14 0 P04406;P04406-2 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ;;; 282.21 1.3741999999999997e-70 60281200.0 52968.9 53068.5 53148.3 58149.0 56481.2 52187.0 58430.0 60220.0 46553.5 40971.299999999996 False True 61935.48858653735 58336.78996250172 54415.55703805018 54891.10005160157 45414.114313686696 49450.221850037065 52895.08740343332 58639.2888083642 47234.256866930744 48399.07236136766 1.279683381617341 1.205328679172504 1.1243099171769437 1.1341353743675442 0.9383261310176769 1.0217183808983172 1.0928946531969979 1.2115787751165727 0.9759331028962721 1.0 15.562691775965027 -5.242855702323069 1.2870077703112557 1.0555167930380014 1.2939723259416667 0.5254106952968335 0.0739634128869009 0.6179123858357843 1.5110314425019524 0.02439112316459205 0.15626485754099478 5.716685463855082e-06 5.242855702323069 0.23845553290366528 LVINGNPITIFQER ddPTM_PC-9_Lapatinib_30min_R1 4 LVINGNPITIFQER 14 0 P04406;P04406-2 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ;;; 181.31 0.00015387 49411270.0 33145.1 30388.7 34387.200000000004 26135.199999999997 28370.3 29792.9 26657.7 28978.6 29647.6 27516.2 False True 32672.444795933086 30318.336832226167 31560.017154430618 28057.26979247142 26701.614732155853 28518.72711764201 28037.905268872124 30325.05154758043 26308.37508493141 32272.338506968168 1.0123978090053354 0.9394527398651294 0.9779278048789756 0.8693906636611833 0.8273839445006597 0.8836895135902318 0.8687906289411982 0.9396608039740509 0.8151989072391196 1.0 14.978010501228326 -5.759158966635779 24.999531977554874 0.8804945063890494 0.9728788012465696 0.37692594084427467 0.05276503962830437 58.21970916687541 638228.5320575205 0.013673582361593235 0.02229908080505503 1.7411694291663197e-06 5.759158966635779 0.0923842948575202 LVINGNPITIFQERDPS(ph)K ddPTM_PC-9_AZD4547_30min_R2 2 LVINGNPITIFQERDPSK 18 1 P04406;P04406-2 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 LVINGNPIT(0.016)IFQERDPS(0.984)K;LVINGNPIT(0.035)IFQERDPS(0.965)K 88.765 0.00071164 25356000.0 54301.0 50750.0 40903.0 41002.0 54384.0 51993.0 55531.0 56144.0 53095.0 47321.0 True False 71567.58846903522 67153.94502965934 40360.59949445458 31549.622374585208 46833.720336171806 48741.869490791745 60473.15142219857 47468.23486077214 55901.49330440919 45664.306193391385 1.5672544802485713 1.4706003578650226 0.8838544337786443 0.6909033554779186 1.02560893267113 1.0673953806363918 1.3242980450877921 1.0395041295435652 1.224183568401601 1.0 15.478779293227653 -5.178342228154919 5.74864189035671 1.0332642508570717 1.535674775443809 0.5887655737235142 0.16313100342224657 0.17002734044266674 9.111960575945375 0.04642123145102541 0.12764453224752112 6.632202406159017e-06 5.178342228154919 0.5024105245867372 LVINGNPITIFQERDPS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LVINGNPITIFQERDPSK 18 1 P04406;P04406-2 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 LVINGNPIT(0.008)IFQERDPS(0.992)K;LVINGNPIT(0.002)IFQERDPS(0.998)K 73.809 0.0031521 66663000.0 56082.0 59373.0 40818.0 56961.0 56181.0 43798.0 58299.0 43074.0 42947.0 34103.7 True False 65575.57493000966 65267.1590575128 41791.25592312701 53769.659840053624 45172.73634868297 41501.15577802755 52776.49667179114 41943.353140675514 43575.018627258425 40286.43084525932 1.6277335458652633 1.6200779688874591 1.037353149591428 1.3346841284248674 1.1212891139995005 1.0301522102425504 1.3100315804720035 1.0411285452856436 1.0816301596592315 1.0 15.298006375903839 -5.254271854822302 24.703105363264736 1.132360434921701 1.6239058498583743 0.7709411421605965 0.10979199394775323 206.68868872270463 712353.8052726196 0.02733944131572854 0.06910828269039057 5.568370771433698e-06 5.254271854822302 0.49154541493667336 LVINGNPITIFQERDPS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 LVINGNPITIFQERDPSK 18 1 P04406;P04406-2 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 LVINGNPIT(0.089)IFQERDPS(0.911)K 46.578 0.045114 19211000.0 16443.0 13702.0 10841.0 12798.0 13161.0 9435.9 11619.0 10606.0 9367.3 9235.3 True False 16208.5198047231 13670.273860848369 9949.694827470177 13739.207612876475 12386.895855521547 9032.348553157228 12220.574967796372 11098.793479106578 8312.256031958006 10831.609299736274 1.496409199796169 1.262072281464326 0.9185795528751606 1.2684364098334857 1.1435877636228202 0.8338879572933955 1.1282326226532116 1.02466708057655 0.767407298577543 1.0 13.402959985955114 -1.522878745280342 0.5057655615013803 0.9762451728432104 17.672507231476175 0.5543012257667579 0.14036284169868637 88.07041817003433 0.9209354843554628 0.07763534455405495 1566.7610946277111 0.02999999999999969 1.522878745280342 16.696262058632964 LVINGNPITIFQERDPS(ph)KIK ddPTM_PC-9_AZD4547_30min_R2 1 LVINGNPITIFQERDPSKIK 20 2 P04406;P04406-2 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 LVINGNPITIFQERDPS(1)KIK 58.711999999999996 0.005340600000000001 149090000.0 31545.0 28613.0 31476.0 39070.0 42805.0 35309.0 36554.0 37704.0 34538.0 41813.0 True False 41575.653823239234 37861.59269228851 31058.607673946957 30063.015125482725 36862.26461808316 33101.122648248165 39807.23518551887 31877.713151726824 36363.6081692755 40349.139596886685 1.0303975311148192 0.9383494436448873 0.7697464675639185 0.7450720244801049 0.9135824205016612 0.820367496778103 0.9865696166812531 0.7900469122812842 0.9012238806718271 1.0 15.300250289420799 LVINGNPITIFQERDPSK ddPTM_PC-9_AZD4547_30min_R2 2 LVINGNPITIFQERDPSK 18 1 P04406;P04406-2 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 95.197 0.001181 48989000.0 149236.0 121414.0 149172.0 240830.0 222304.0 154088.0 154558.0 184191.0 184793.0 200425.0 False True 196689.94369836542 160658.70111982388 147193.88181274675 185310.36428640902 191440.92684635796 144452.85300131005 168313.36258148024 155728.51323811075 194560.78071761364 193408.1817546221 1.016968061609239 0.830671689596112 0.7610530251480898 0.9581309467120329 0.9898284814509036 0.7468807766601006 0.8702494437128839 0.8051805865983698 1.0059594116057295 1.0 17.561289300932785 -8.27967854091265 23.84765949751825 1.0029798081818122 0.8697901150200014 0.2625150850903196 0.0874801324183097 707.274894115654 924744.6878413113 0.0841133585412341 0.021917567424691788 5.251960596585585e-09 8.27967854091265 -0.13318969316181084 LVINGNPITIFQERDPSK ddPTM_PC-9_Lapatinib_30min_R1 2 LVINGNPITIFQERDPSK 18 1 P04406;P04406-2 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 91.616 0.0015815999999999998 19742400.0 139443.0 100252.0 108962.0 98511.0 123804.0 117561.0 118130.0 100767.0 133851.0 145233.0 False True 137454.51724928533 100019.87265346463 100003.56496548338 105755.82756306272 116522.09212802917 112533.19007807587 124246.19338547079 105449.00268801943 118775.29086648334 170336.33053919201 0.8069594831248227 0.5871904856518642 0.5870947474853226 0.6208647751674431 0.6840706956594856 0.6606528960783475 0.7294168718568437 0.6190634866573992 0.697298635531865 1.0 17.378026650490995 -13.012275434520564 0.37587162154979437 2.265786052027264 0.6511941897144712 0.7071807869332114 0.0645726933003722 85.92752963360867 1.9644768045296388 85.79907958466839 0.04405721416786831 9.721304919676073e-14 13.012275434520564 -1.614591862312793 LVINSGNGAVEDRKPS(ph)GLNGEASK ddPTM_PC-9_AZD4547_30min_R2 1 LVINSGNGAVEDRKPSGLNGEASK 24 2 P16070;P16070-5;P16070-7;P16070-3;P16070-4;P16070-8;P16070-17;H0Y2P0;H0YD13;H0YE40;P16070-10;P16070-16;P16070-11;P16070-13;P16070-14;P16070-12;P16070-18;P16070-6;J3KN83 P16070 CD44 CD44 antigen 1 LVINSGNGAVEDRKPS(0.918)GLNGEAS(0.081)K 45.243 0.016962 28142000.0 59282.0 52141.0 58555.0 65150.0 51903.0 23963.0 46833.0 52823.0 42608.0 37918.0 True False 78132.44285779899 68994.55857717167 57778.52244084265 50130.674057466116 44697.16436099452 22464.58982185762 51001.046272457286 44660.41910178407 44860.17189404398 36590.502361340965 2.135320310342293 1.8855865354302057 1.5790579170043728 1.3700460726778865 1.2215509893687193 0.6139459250931787 1.39383290693329 1.2205467599419797 1.22600590314497 1.0 15.159181602530088 -5.436348967729378 1.1522203930414692 1.1144369361757698 2.1760203846745108 0.7667616169052001 0.1973093963843283 0.33819346215135554 0.7350280397673826 0.06984462994979121 0.3308541248534663 3.661432501009001e-06 5.436348967729378 1.061583448498741 up LVINSGNGAVEDRKPS(ph)GLNGEASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LVINSGNGAVEDRKPSGLNGEASK 24 2 P16070;P16070-5;P16070-7;P16070-3;P16070-4;P16070-8;P16070-17;H0Y2P0;H0YD13;H0YE40;P16070-10;P16070-16;P16070-11;P16070-13;P16070-14;P16070-12;P16070-18;P16070-6;J3KN83 P16070 CD44 CD44 antigen 1 LVINS(0.001)GNGAVEDRKPS(0.991)GLNGEAS(0.009)K 62.049 0.0083089 6540200.0 20654.0 9093.1 12477.0 11384.0 21730.0 12914.0 11659.0 18869.0 16706.0 7958.8 True False 24150.31426490532 9995.802873795656 12774.498999285994 10746.191387425968 17472.16249011021 12236.767106202291 10554.575116149734 18373.70874335809 16950.293645353082 9401.66743817387 2.568726709779914 1.06319468748803 1.3587482309167112 1.143009094726419 1.8584110324055358 1.30155285609412 1.1226280003581788 1.9543031982555321 1.8029029166176735 1.0 13.198700934159607 -4.750108176614422 24.966248122500836 1.4235282126452122 2.568729250413562 0.5237963373551584 0.3335106501475792 420.31816165827905 926034.9492539702 0.08402738328562492 1.2792051155786788 1.777836520944143e-05 4.750108176614422 1.14520103776835 LVLAES(ph)PQPK ddPTM_PC-9_AZD4547_30min_R2 2 LVLAESPQPK 10 0 E7EUR8;A0A1B0GVL4;P78312-4;P78312-6;P78312-2;P78312-5;P78312 E7EUR8 FAM193A Protein FAM193A 1 LVLAES(1)PQPK;LVLAES(1)PQPK 128.28 0.00028478 32005000.0 160609.0 119434.0 178415.0 223770.0 205113.0 188283.0 176554.0 188494.0 180517.0 195250.0 True False 211679.32112526993 158038.70484083402 176049.10052570983 172183.28371203682 176636.6004580985 176509.63424566237 192266.9639695815 159366.58346121333 190058.76008724025 188414.35692947498 1.1234776615483884 0.8387827096423931 0.9343720053753994 0.9138543713868176 0.9374901325816429 0.9368162656083122 1.02044752376035 0.8458303605858737 1.0087275894712249 1.0 17.523549375065834 LVLAES(ph)PQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LVLAESPQPK 10 0 E7EUR8;A0A1B0GVL4;P78312-4;P78312-6;P78312-2;P78312-5;P78312 E7EUR8 FAM193A Protein FAM193A 1 LVLAES(1)PQPK;LVLAES(1)PQPK;LVLAES(1)PQPK;LVLAES(1)PQPK 121.08 0.00065265 34593200.0 173107.0 170798.0 171384.0 230987.0 228438.0 195609.0 214424.0 197179.0 182016.0 160433.0 True False 202410.59608090253 187753.69667534184 175470.4445374397 218045.5472599583 183677.21375590423 185350.91969003595 194112.20642467556 192003.26017841944 184677.6396595586 189518.23291307056 1.0680270334398143 0.9906893589571506 0.9258763225062657 1.1505254344576588 0.9691796453175799 0.9780110168875091 1.0242402719832882 1.0131123387293757 0.9744584297821504 1.0 17.531977126357674 LVLAES(ph)PQPK ddPTM_PC-9_Lapatinib_30min_R1 2 LVLAESPQPK 10 0 E7EUR8;A0A1B0GVL4;P78312-4;P78312-6;P78312-2;P78312-5;P78312 E7EUR8 FAM193A Protein FAM193A 1 LVLAES(1)PQPK;LVLAES(1)PQPK 130.44 0.00021314 37447000.0 205025.0 180296.0 184151.0 175976.0 172815.0 166180.0 147922.0 147785.0 167098.0 125925.0 True False 202101.30590302017 179878.53568935295 169010.81562341645 188917.8620787269 162650.3614673626 159072.86878450055 155580.6773720954 154651.63061566697 148277.6636200526 147690.96846548462 1.3684066669943413 1.217938629276377 1.1443544407586053 1.2791429566857841 1.1012884752351935 1.0770656488834378 1.0534203884542515 1.047129910667551 1.0039724511299761 1.0 17.172222080170904 -2.6921036594504826 0.23097470328409994 0.9705561485494001 2.2674043354642825 0.8299963386486775 0.04811144401496461 12.07268622394281 0.2528212733993703 0.07416986902853545 5.300853720247491 0.002031871976289218 2.6921036594504826 1.2968481869148825 LVLGSARNSSIS(ph)GPFGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LVLGSARNSSISGPFGSR 18 1 Q13610;B4DJV5 Q13610 PWP1 Periodic tryptophan protein 1 homolog 1 LVLGSARNSS(0.002)IS(0.499)GPFGS(0.499)R 42.818000000000005 0.043281 5781500.0 36557.0 35706.0 33648.0 47554.0 48823.0 43545.0 41519.0 37668.0 35870.0 32398.0 True False 42745.37806633795 39250.65570726678 34450.29593075061 44889.70355214814 39256.48362883803 41261.42354340859 37586.01974847076 36679.25491254504 36394.53089062703 38271.50093757313 1.1168983974802142 1.0255844360870718 0.9001553397904224 1.172927699526871 1.0257367144516114 1.0781239965140772 0.9820889912255989 0.9583960391930983 0.9509564558231531 1.0 15.223982861499978 -7.385678451361701 5.203518585428494 0.9668958516787673 1.0490125829482801 0.2531630307035172 0.06747876411051663 0.34512492376147363 13.201972688298317 0.02919777965756275 0.019328370846472088 4.114542462418403e-08 7.385678451361701 0.0821167312695128 LVLPSNT(ph)PNVR ddPTM_PC-9_AZD4547_30min_R2 1 LVLPSNTPNVR 11 0 H0Y8J2;Q03188;H0Y9W1 H0Y8J2 CENPC Centromere protein C 1 LVLPS(0.065)NT(0.935)PNVR 130.15 0.00054629 9820700.0 23307.0 36762.0 46954.0 62043.0 51638.0 42779.0 47629.0 54347.0 49861.0 57992.0 True False 30718.14118428395 48644.597579908135 46331.35928080143 47739.94490479464 44468.955036761574 40104.02236736833 51867.88873040096 45948.919919820175 52496.55066675101 55961.71773139104 0.5489134792417744 0.8692477563572274 0.8279116717464949 0.8530821933297358 0.7946317025186176 0.7166331555414795 0.9268459016815759 0.821077725676131 0.9380796872377581 1.0 15.772152625907115 -1.5439166997920108 0.07775620336346681 1.1537275738311186 5.808547215575596e-13 0.4685495726898198 0.08785323440101081 208.9318081002959 1.1972206223915194 2.7822179908589306 25.99430299916081 0.02858138698432209 1.5439166997920108 -1.1537275738305377 LVLPSNT(ph)PNVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LVLPSNTPNVR 11 0 H0Y8J2;Q03188;H0Y9W1 H0Y8J2 CENPC Centromere protein C 1 LVLPS(0.03)NT(0.97)PNVR;LVLPS(0.04)NT(0.96)PNVR;LVLPS(0.008)NT(0.992)PNVR 130.15 0.00054629 17798700.0 82648.0 72816.0 90982.0 94657.0 105293.0 85797.0 103158.0 80733.0 77369.0 78553.0 True False 96638.67402759231 80044.6912558209 93151.35593115647 89353.67517213472 84661.59250212484 81297.65428301353 93386.12744075597 78613.84429368409 78500.37525723224 92794.03707479432 1.0414319397452134 0.8626059796418046 1.0038506661378914 0.9629247523751275 0.9123602676526023 0.8761086040203809 1.0063806941116744 0.8471863793394327 0.8459635740813709 1.0 16.501744480602504 -6.268676599177666 7.081758215814084 0.9095905229222 0.962864178268086 0.12751741227126334 0.06671935993804465 0.3053820567044834 102.7073448548176 0.019922945740015217 0.02379222408498995 5.386707586454304e-07 6.268676599177666 0.05327365534588602 LVLPSNT(ph)PNVR ddPTM_PC-9_Lapatinib_30min_R1 2 LVLPSNTPNVR 11 0 H0Y8J2;Q03188;H0Y9W1 H0Y8J2 CENPC Centromere protein C 1 LVLPS(0.079)NT(0.921)PNVR;LVLPS(0.003)NT(0.997)PNVR 137.62 0.00022799999999999999 20563800.0 66081.0 86962.0 85736.0 81118.0 74910.0 76208.0 65054.0 63430.0 91708.0 61822.0 True False 65138.6728222288 86760.64483192924 78687.11703053059 87083.6883217154 70503.94107872646 72948.76148952475 68422.17780833326 66377.18936259954 81378.87931194736 72507.850327363 0.8983671771833894 1.1965689844646727 1.0852220369969463 1.2010242743171184 0.972362864992009 1.0060808748317747 0.9436519976722039 0.9154483143951397 1.1223457728305677 1.0 16.145849581783622 -6.294493252158665 24.75139366117259 0.9872425153429004 1.1018099164022266 0.2211392969404582 0.09302330693620513 764.7759361169308 572677.0141981564 0.027775233894882533 0.03149586280114808 5.075826255219513e-07 6.294493252158665 0.11456740105932617 LVLVS(ph)PTSEQYDSLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LVLVSPTSEQYDSLLR 16 0 O00178 O00178 GTPBP1 GTP-binding protein 1 1 LVLVS(0.485)PT(0.485)S(0.03)EQYDSLLR 140.77 5.7592e-07 0.0 3659.0 3742.9 5227.6 5003.5 4916.0 4924.5 4238.8 4131.9 3061.9 3386.4 True False 4278.3964314558225 4114.470376035648 5352.245809783402 4723.170116565868 3952.7450898012776 4666.250550913208 3837.2701777455586 4023.442003109927 3106.674494954307 4000.327513272352 1.0695115380580438 1.0285333794257072 1.3379519031943343 1.1806958557506246 0.9881053680446902 1.1664671293616449 0.9592390035601337 1.005778149354243 0.7766050366243593 1.0 11.965902405269857 -7.440271114811505 1.3209235930407788 0.9007558408147962 1.1379369623609028 0.42746367401940144 0.108510635619116 0.44237746083221346 1.4734669125872133 0.0770183904733941 0.038336776539875876 3.628514686082846e-08 7.440271114811505 0.2371811215461066 LVNHFVEEFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LVNHFVEEFK 10 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 95.48299999999999 0.0049513000000000005 2034100.0 16327.0 15203.0 14468.0 20208.0 18440.0 20518.0 19357.0 18793.0 16731.0 13862.0 False True 19090.8386270509 16712.253366873272 14812.97199019555 19075.811275219967 14826.81437264759 19441.999960125322 17523.36482745606 18299.703662829415 16975.659223057737 16375.070868468376 1.1658476949746808 1.0205912084969457 0.90460506150964 1.1649299980711596 0.9054503941841199 1.1872925690698894 1.0701245184348376 1.1175343184661928 1.0366769926929504 1.0 13.999213529947118 -6.78018106754602 24.999316853083144 1.0889089332026949 1.0319109934984434 0.06328322346303716 0.09457533427178896 670.7866271496277 894748.7014690725 0.031883611174370774 0.02816131317475032 1.6588951309868534e-07 6.78018106754602 -0.05699793970425149 LVPGGGATEIELAK ddPTM_PC-9_Lapatinib_30min_R1 2 LVPGGGATEIELAK 14 0 P50990-2;P50990;P50990-3 P50990-2 CCT8 T-complex protein 1 subunit theta 0 ; 142.19 0.00061187 9443500.0 86753.0 65375.0 68272.0 68827.0 69656.0 68233.0 58871.0 56872.0 63793.0 53219.0 False True 85515.88631144832 65223.62820412805 62658.939697541246 73888.76718014115 65558.971028965 65314.83364889165 61919.05232198468 59514.48074144348 56607.96056992909 62417.833240140004 1.3700553491250365 1.044951816145128 1.0038627815943824 1.1837765482161011 1.0503243644607159 1.046413024265133 0.992008999795998 0.9534852085056131 0.9069196675274099 1.0 15.929670656256086 LVPLLDTGDIIIDGGNSEYR ddPTM_PC-9_Lapatinib_30min_R1 2 LVPLLDTGDIIIDGGNSEYR 20 0 P52209-2;P52209;K7EMN2;K7EM49 P52209-2 PGD 6-phosphogluconate dehydrogenase, decarboxylating 0 ; 157.86 6.4003e-05 135927000.0 212229.0 197032.0 200187.0 209345.0 206514.0 202980.0 183885.0 185528.0 228992.0 208435.0 False True 209202.57554196758 196575.78450960998 183728.39760416662 224740.92965444794 194367.25254214567 194299.01856949067 193405.66554378497 194148.30818326326 203200.50956733842 244462.71202782073 0.8557647659499072 0.8041135716732086 0.7515600071689366 0.9193260100496292 0.7950793433070724 0.7948002251868119 0.7911458722660931 0.7941837287691077 0.8312126944914752 1.0 17.899254901679612 -8.62708108070045 9.160702763307324 0.9999999968047955 0.8124741613260795 0.626592182898523 0.04298397790715392 9.558225372581335 840.7657069490887 0.041048215480471856 0.010604356634728904 2.360037584330772e-09 8.62708108070045 -0.18752583547871593 LVPS(ph)QEETK ddPTM_PC-9_AZD4547_30min_R2 4 LVPSQEETK 9 0 P49321;P49321-3;P49321-4 P49321 NASP Nuclear autoantigenic sperm protein 1 LVPS(1)QEETK;LVPS(1)QEETK;LVPS(1)QEETK;LVPS(0.999)QEET(0.001)K 115.33 0.0019855 111632000.0 414092.0 446571.0 439351.0 339137.0 379909.0 506741.0 493991.0 532920.0 485714.0 389057.0 True False 545764.6423513328 590916.3425781275 433524.91867315635 260954.204264419 327165.19305668486 475054.4051628734 537955.2420126288 450569.4592833191 511387.850435216 375436.2328497336 1.4536813301388847 1.5739459617224496 1.1547231746454063 0.6950693125265418 0.8714267948337076 1.2653397930108985 1.4328804599633371 1.200122470501288 1.3621164013754004 1.0 18.518208363897422 -6.959407175033249 24.999765592347384 1.2774083941814565 1.1403522545119507 0.03267233861510832 0.25908656433387806 553.077637952908 340620.49194183236 0.1033475119407295 0.0911438183088271 1.0979759437023843e-07 6.959407175033249 -0.1370561396695058 LVPS(ph)QEETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LVPSQEETK 9 0 P49321;P49321-3;P49321-4 P49321 NASP Nuclear autoantigenic sperm protein 1 LVPS(1)QEETK;LVPS(1)QEETK;LVPS(1)QEETK;LVPS(1)QEETK 111.5 0.002231 114042000.0 695343.0 1025410.0 867560.0 748750.0 791200.0 554622.0 753960.0 531897.0 518276.0 519955.0 True False 813050.8362497354 1127205.9281013985 888245.9206396207 706799.9649802538 636170.0396767223 525536.6459637695 682539.4506023045 517935.26734145527 525854.8060181378 614218.7255384852 1.323715481869971 1.8351865243332945 1.446139434874598 1.1507300829368279 1.0357385947798845 0.8556180788904341 1.111231914989115 0.8432423920117084 0.8561360703503809 1.0 19.228392970517618 -5.857768938904207 1.980274240653089 0.9438526268618916 1.5952385642673215 0.7764048757516986 0.14117448308566635 0.137872682531583 1.1028995594788602 0.04262802587802477 0.07699827802501825 1.387493831745717e-06 5.857768938904207 0.6513859374054298 LVPS(ph)QEETK ddPTM_PC-9_Lapatinib_30min_R1 1 LVPSQEETK 9 0 P49321;P49321-3;P49321-4 P49321 NASP Nuclear autoantigenic sperm protein 1 LVPS(1)QEETK 108.98 0.0023989999999999997 14808000.0 58905.0 81753.0 72734.0 76178.0 86043.0 84631.0 88261.0 89923.0 77105.0 76253.0 True False 58065.00389814596 81563.7059513895 66754.09128135943 81780.38424235828 80982.11990704662 81011.52941449666 92830.72271561026 94101.15086005113 68420.62294835452 89433.22944926404 0.6492553635344965 0.912006716671917 0.7464126219352215 0.9144295106636259 0.9055036970680816 0.905832540246743 1.0379891600389275 1.0521944856462466 0.7650469894656987 1.0 16.44852335250583 -3.480402858632198 0.42357297605268107 0.9674607337297271 8.500650605076747e-17 0.4345916339686363 0.09393359528720631 14.992574918946275 0.8884709949680716 0.06505467926219095 9.215643249522858 0.00033082410128361335 3.480402858632198 -0.967460733729727 LVPS(ph)QEETKLSVEESEAAGDGVDTK ddPTM_PC-9_AZD4547_30min_R2 4 LVPSQEETKLSVEESEAAGDGVDTK 25 1 P49321;P49321-3;P49321-4 P49321 NASP Nuclear autoantigenic sperm protein 1 LVPS(0.773)QEET(0.222)KLS(0.006)VEESEAAGDGVDTK;LVPS(0.726)QEET(0.224)KLS(0.047)VEES(0.003)EAAGDGVDTK;LVPS(0.991)QEET(0.009)KLSVEESEAAGDGVDTK;LVPS(0.437)QEET(0.437)KLS(0.113)VEES(0.012)EAAGDGVDTK 89.29899999999999 3.2416000000000004e-06 68918600.0 89518.0 80007.0 114107.0 140519.0 128781.0 133429.0 104397.0 116743.0 114681.0 129809.0 True False 117982.86190992991 105867.69812784143 112593.86662381078 108124.51554690841 110901.98107186916 125085.6635371464 113688.13075621318 98703.0518372601 120742.8035340982 125264.42642078445 0.9418704518200999 0.8451537372008066 0.8988494965489155 0.8631701643984688 0.8853429839636242 0.9985729158010308 0.9075851301495245 0.7879575603188395 0.9639033761149606 1.0 16.934617239351816 -6.57581520204729 24.99982572045358 0.9196397267026718 0.8837266473594121 0.10117663165499968 0.061361909896457685 287.4014227610644 135726.31520955975 0.02041424075173933 0.020414246615501886 2.655735371538852e-07 6.57581520204729 -0.03591307934325971 LVPS(ph)QEETKLSVEESEAAGDGVDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LVPSQEETKLSVEESEAAGDGVDTK 25 1 P49321;P49321-3;P49321-4 P49321 NASP Nuclear autoantigenic sperm protein 1 LVPS(0.806)QEET(0.191)KLS(0.003)VEES(0.001)EAAGDGVDTK;LVPS(0.485)QEET(0.485)KLS(0.031)VEESEAAGDGVDTK;LVPS(0.527)QEET(0.463)KLS(0.007)VEES(0.003)EAAGDGVDTK;LVPS(0.948)QEET(0.045)KLS(0.005)VEES(0.002)EAAGDGVDTK 79.17699999999999 4.6291999999999997e-05 53086200.0 94443.0 64109.4 81213.7 118278.0 130131.0 114035.0 117312.9 139463.0 107308.0 85142.0 True False 110430.33456572347 70473.75754773566 83150.14261267234 111651.26712244985 104632.76470319973 108054.80385285562 106200.17284015444 135802.24402326316 108877.17649320888 100577.5706162987 1.0979618406872529 0.7006905925038849 0.8267264968040277 1.1101010537269493 1.0403190697692581 1.0743429493349208 1.055903142116107 1.3502239434808565 1.0825194506693048 1.0 16.617949086056754 -5.76589104481274 24.58149315847503 1.1108757867993442 0.8576827080527932 0.39516835420342833 0.1276947302425688 80.36962784407218 443794.74079634616 0.035626595933495826 0.05497343176409369 1.7143873566438392e-06 5.76589104481274 -0.25319307874655095 LVPS(ph)QEETKLSVEESEAAGDGVDTK ddPTM_PC-9_Lapatinib_30min_R1 3 LVPSQEETKLSVEESEAAGDGVDTK 25 1 P49321;P49321-3;P49321-4 P49321 NASP Nuclear autoantigenic sperm protein 1 LVPS(0.481)QEET(0.481)KLS(0.023)VEES(0.008)EAAGDGVDT(0.007)K;LVPS(0.953)QEET(0.042)KLS(0.004)VEES(0.001)EAAGDGVDTK;LVPS(0.587)QEET(0.386)KLS(0.024)VEES(0.002)EAAGDGVDTK 63.398 0.00065041 23573400.0 97676.0 77830.0 92178.0 81673.0 79540.0 84057.0 71053.0 71879.0 96060.0 70836.0 True False 96283.1223284153 77649.78941686102 84599.48065736966 87679.5048731409 74861.61358165675 80462.07805643746 74731.77667500086 75218.7607471906 85240.71124335575 83079.90821696306 1.1589218668486256 0.9346398074258666 1.0182904925272454 1.0553635259702745 0.9010796375238616 0.9684902136183259 0.8995168420244151 0.9053784767161384 1.0260087315064161 1.0 16.342212001906717 -6.253544336511821 24.92614665340794 0.9437403614939441 1.0324698149931182 0.3178041369983572 0.0648683963525873 728.1024796472016 2298756.459137434 0.018633514718800037 0.02359454886080434 5.577706572139322e-07 6.253544336511821 0.08872945349917405 LVPSQEET(ph)KLSVEESEAAGDGVDTK ddPTM_PC-9_Lapatinib_30min_R1 1 LVPSQEETKLSVEESEAAGDGVDTK 25 1 P49321;P49321-3;P49321-4 P49321 NASP Nuclear autoantigenic sperm protein 1 LVPS(0.206)QEET(0.79)KLS(0.004)VEES(0.001)EAAGDGVDTK 71.696 0.00026743 16073000.0 92159.0 64088.0 71469.0 75246.0 70242.0 69993.0 59644.0 59233.0 76562.0 59239.0 True False 90844.79576010931 63939.60817355502 65593.09469831792 80779.84185329775 66110.50366108543 66999.56255165217 62732.07447966664 61985.18142069775 67938.78132639802 69478.38221899421 1.3075260657878973 0.9202806129253109 0.9440791884239623 1.1626615254034212 0.9515262380852031 0.964322432558535 0.9029006214038868 0.8921506149254013 0.9778405765444652 1.0 16.084276541314985 -6.416657914590352 9.244043584373319 0.940121107751773 1.0619294690970893 0.2694225178888692 0.10663097013347311 0.5571950576905581 44.72322768947058 0.03284354228637087 0.03722719022760195 3.8312640579468647e-07 6.416657914590352 0.12180836134531625 LVPVGYGIR ddPTM_PC-9_Lapatinib_30min_R1 2 LVPVGYGIR 9 0 P29692-2;P29692;E9PRY8;A0A087X1X7;E9PK01;P29692-3;P29692-4;E9PQZ1;H0YE72;H0YE58;E9PQC9 P29692-2 EEF1D Elongation factor 1-delta 0 ; 96.04799999999999 0.024097999999999998 11705700.0 104778.0 91820.0 106371.0 97832.0 93375.0 101330.0 91555.0 87795.0 92058.0 84003.0 False True 103283.84650606818 91607.3964314041 97625.58698393423 105026.89163798503 87882.86608231328 96996.35211176692 96295.26991794442 91874.27621140516 81689.45862628403 98522.80662303817 1.0483242413225844 0.9298090418993707 0.9908932797404278 1.066016034640917 0.892005304097408 0.9845065872198335 0.9773906491152184 0.9325178540937105 0.8291426262229735 1.0 16.588170106081662 -7.8577606211965305 3.9615644614715673 0.9052610786366251 0.9820896196847548 0.18352500511868985 0.06105459390917479 0.33432214843741925 9.680669607553703 0.034823798209747146 0.015745428448505964 1.3875204056007685e-08 7.8577606211965305 0.07682854104812975 LVPVS(ph)PLPPK ddPTM_PC-9_AZD4547_30min_R2 2 LVPVSPLPPK 10 0 O95396 O95396 MOCS3 Adenylyltransferase and sulfurtransferase MOCS3;Molybdopterin-synthase adenylyltransferase;Molybdopterin-synthase sulfurtransferase 1 LVPVS(1)PLPPK;LVPVS(1)PLPPK 122.51 0.0005327000000000001 36423000.0 354890.0 357640.0 444610.0 601900.0 547400.0 469240.0 403880.0 483290.0 404730.0 441850.0 True False 467737.63782943017 473240.1359686176 438714.18089698703 463141.25426230015 471402.9588117917 439898.3486211426 439824.5375807671 408608.6353993752 426123.2015273285 426380.96598867315 1.0969946483067343 1.1098997697312531 1.0289253411669448 1.086214655920179 1.105591000570871 1.0317025939493476 1.03152948340675 0.9583181895840771 0.9993954597369351 1.0 18.701783510829713 -7.2132721137696425 1.7282611725118053 0.986221936462962 1.0832551766208385 0.7116434978101266 0.026590586491547115 0.201018298395691 1.1755459274943578 0.014144892985462797 0.009057979328309063 6.119668345088154e-08 7.2132721137696425 0.09703324015787651 LVPVS(ph)PLPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LVPVSPLPPK 10 0 O95396 O95396 MOCS3 Adenylyltransferase and sulfurtransferase MOCS3;Molybdopterin-synthase adenylyltransferase;Molybdopterin-synthase sulfurtransferase 1 LVPVS(1)PLPPK;LVPVS(1)PLPPK;LVPVS(1)PLPPK 108.7 0.005656100000000001 25210000.0 130909.0 111563.0 120561.0 146449.0 160106.0 141885.0 150342.0 145310.0 130497.0 124556.0 True False 153069.30812939326 122638.23734581853 123435.63147013889 138243.93732406394 128734.37863053785 134444.30082573261 136100.51737817834 141495.76646867182 132405.27174893089 147137.01681524623 1.0403181432011495 0.8334968317307276 0.8389162302042037 0.9395591967020172 0.8749285626212212 0.9137353993967995 0.9249916868239488 0.9616598836331044 0.8998773701874534 1.0 17.166800720740774 -9.08817726032142 0.4554328764287756 1.0057776604295294 0.8996343642497171 0.15914022106401304 0.05761471762220084 3.9390815694572536 1.4453516842875471 0.11609792978666765 0.033919166169668113 8.162491455779775e-10 9.08817726032142 -0.10614329617981233 LVPVS(ph)PLPPK ddPTM_PC-9_Lapatinib_30min_R1 1 LVPVSPLPPK 10 0 O95396 O95396 MOCS3 Adenylyltransferase and sulfurtransferase MOCS3;Molybdopterin-synthase adenylyltransferase;Molybdopterin-synthase sulfurtransferase 1 LVPVS(1)PLPPK 98.182 0.004857899999999999 11594000.0 140470.0 121190.0 125250.0 114140.0 113760.0 108740.0 107950.0 101550.0 119720.0 81398.0 True False 138466.8720409569 120909.39200089154 114952.42847898186 122534.2363598784 107068.86046076528 104089.44368532076 113539.12279659336 106268.38372650111 106235.87289251034 95467.53584398278 1.4504079404253767 1.2664974635826671 1.2040996707701992 1.283517326351957 1.1215211486734284 1.090312458210174 1.1892956259198306 1.1131363430199932 1.1127957996750397 1.0 16.54272260129089 -1.5228787452803376 0.2847138381129626 1.065656777551329 3.7760111691081 0.8032757863185438 0.05336023032700043 23.74752067278669 0.3358926575443745 0.05873876970504544 32.200868334938946 0.029999999999999995 1.5228787452803376 2.7103543915567707 LVQAFQFTDK ddPTM_PC-9_AZD4547_30min_R2 1 LVQAFQFTDK 10 0 A0A0A0MSI0;Q06830;A0A0A0MRQ5 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 157.24 0.0016995 8853600.0 34261.0 34671.0 45347.0 59403.0 50994.0 49525.0 41365.0 57760.0 42492.0 39171.0 False True 45155.28532692978 45877.72272164174 44745.669150796566 45708.55611720118 43914.36332051238 46428.19392094055 45046.4048653769 48834.519192757885 44738.04037086269 37799.635212724475 1.194595796303589 1.2137080811350778 1.183759284950291 1.2092327309501212 1.1617668549809048 1.2282709518136155 1.191715333014985 1.2919309648871622 1.183557463427651 1.0 15.206084691262125 -8.559688307863828 23.30203675226285 0.9999999991934864 1.209027551384565 0.7854477798398888 0.032627106921458086 3630.168462686365 2298048.1894134316 0.03114824605774739 0.008042442524727697 2.75620611635863e-09 8.559688307863828 0.2090275521910786 LVQAFQFTDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LVQAFQFTDK 10 0 A0A0A0MSI0;Q06830;A0A0A0MRQ5 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 ; 143.89 0.00054506 24186000.0 111829.0 102327.0 102503.0 122130.0 141177.0 118016.0 113082.0 109867.0 106445.0 94020.0 False True 130759.44097657067 112485.34830441639 104947.0602647923 115287.45205080243 113514.38029757439 111827.03320470556 102370.05431721814 106983.10766370897 108001.55675084463 111065.08173808931 1.1773226916171913 1.012787696583849 0.9449149869828181 1.038017081936429 1.0220528227338 1.0068604052209051 0.921712321417315 0.9632470078759197 0.9724168483982301 1.0 16.761045786919894 -4.772033823766521 3.845509043834566 0.9839009265376235 1.1982918303501928 0.7494492853302794 0.033394050115137096 0.13296808314792455 3.5401697104901975 0.009081911319138063 0.08191366835932294 1.690309281679255e-05 4.772033823766521 0.2143909038125693 LVQAFQFTDK ddPTM_PC-9_Lapatinib_30min_R1 2 LVQAFQFTDK 10 0 A0A0A0MSI0;Q06830;A0A0A0MRQ5 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 ; 180.67 0.0072887 98316000.0 272370.0 261486.0 274431.0 261602.0 259743.0 254795.0 271929.0 223118.0 248884.0 238114.0 False True 268485.9538534588 260880.5452326515 251868.3425142951 280841.08375868987 244465.42741438598 243898.0118061549 286008.1530611844 233484.87681230486 220852.06305529192 279271.68763303856 0.9613790646986309 0.9341460548462295 0.9018756775847923 1.005619603401092 0.8753677448879537 0.8733359757063363 1.0241215480353223 0.8360492207112047 0.7908143676400534 1.0 18.09130979606106 -6.778151660632086 0.8323887961293035 0.8890953644882503 0.944249298361 0.053652209038279275 0.0719601130777108 1.8271249904539215 2.7552486577421673 0.04831314743897688 0.04495017507962761 1.6666650922808298e-07 6.778151660632086 0.055153933872749694 LVQGSILK ddPTM_PC-9_Lapatinib_30min_R1 1 LVQGSILK 8 0 P12004 P12004 PCNA Proliferating cell nuclear antigen 0 93.162 0.034239 2480900.0 25684.0 19833.0 23726.0 15086.0 19481.0 24508.0 23687.0 18906.0 23929.0 22511.0 False True 25317.741450131252 19787.077907035884 21775.33986500851 16195.474765420713 18335.165881119632 23459.84997093839 24913.396958618883 19784.441779746274 21233.864036459076 26401.996355977957 0.958932843894541 0.7494538534225531 0.824761111675486 0.6134185668029503 0.6944613442827088 0.8885634879510388 0.9436179227779484 0.749354007666419 0.8042522144978362 1.0 14.68835940095051 -6.777357748880308 24.858335318767104 0.865645945328749 0.7617064746714476 0.20531172713997603 0.1055861479418334 411.6899754783179 642896.2264193466 0.038392467754277015 0.03396846459980473 1.669714624842899e-07 6.777357748880308 -0.10393947065730136 LVQS(ph)PNSYFMDVK ddPTM_PC-9_AZD4547_30min_R2 1 LVQSPNSYFMDVK 13 0 H0YMV8;Q71UM5;C9JLI6;P42677 H0YMV8;P42677 RPS27L;RPS27 40S ribosomal protein S27;40S ribosomal protein S27-like 1 LVQS(0.871)PNS(0.129)YFMDVK 124.09 0.0001579 4480200.0 16371.0 11800.0 20123.0 22837.0 17092.0 20966.0 13427.0 18262.0 15502.0 18280.0 True False 21576.63746204629 15614.119238423255 19856.15587186537 17572.28247813282 14719.070829395581 19654.992705632296 14621.97698845439 15440.027519012196 16321.404072039753 17640.022763998964 1.2231638105411888 0.8851530095692212 1.1256309664400914 0.9961598526956329 0.8344133693203235 1.1142271735468294 0.8289091904289363 0.875283877213771 0.9252484699367655 1.0 14.106564802207197 -1.5228787452803376 0.5490135955846169 0.9279986103031226 11.062199917229455 0.3106330962315319 0.10697149152987126 172.97547486979732 1.5893089563472595 0.051857711423989074 2066.329038520596 0.029999999999999995 1.5228787452803376 10.134201306926332 LVQS(ph)PNSYFMDVK ddPTM_PC-9_Lapatinib_30min_R1 1 LVQSPNSYFMDVK 13 0 H0YMV8;Q71UM5;C9JLI6;P42677 H0YMV8;P42677 RPS27L;RPS27 40S ribosomal protein S27;40S ribosomal protein S27-like 1 LVQS(0.976)PNS(0.024)YFMDVK 120.32 0.00021445 3126500.0 21246.0 20538.0 18342.0 15478.0 19194.0 14870.0 18243.0 16613.0 20071.0 14605.0 True False 20943.02814396078 20490.44552285097 16833.99156216751 16616.303753094384 18065.046656855913 14234.044763663034 19187.533276315462 17384.900628738233 17810.392623000127 17129.454790060776 1.2226325006043273 1.1962111914233475 0.9827511598288169 0.9700427688297386 1.0546188934943805 0.8309689326435667 1.120148510940866 1.0149126660368477 1.0397524522108235 1.0 14.064191612454534 -5.239935244689246 7.085716451889317 1.0010017331474328 1.2110552431474415 0.5835811368739446 0.07021273359179399 0.12411086594686431 28.32584798395854 0.017613054623254878 0.044867777972652 5.755257444834152e-06 5.239935244689246 0.21005351000000871 LVQSPNS(ph)YFMDVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LVQSPNSYFMDVK 13 0 H0YMV8;Q71UM5;C9JLI6;P42677 H0YMV8;P42677 RPS27L;RPS27 40S ribosomal protein S27;40S ribosomal protein S27-like 1 LVQS(0.004)PNS(0.987)Y(0.009)FMDVK 99.927 0.0020988000000000005 6477000.0 33260.0 36780.0 36529.0 41343.0 42283.0 35311.0 38216.0 38470.0 32394.0 24387.0 True False 38890.26108505618 40431.27532944804 37399.989897003965 39026.685745814444 33997.94968105522 33459.22899853716 34595.903820119915 37460.20326233426 32867.700966572986 28808.170052614234 1.3499733240267733 1.403465588255199 1.2982424717952556 1.3547089480011216 1.1801495762820948 1.1614493019663656 1.2009059845500483 1.3003326207085788 1.140915959137445 1.0 14.814190400343403 -1.5228787754397055 0.048826385592805485 0.5031460398823991 2.598628365519115 0.7475531998460767 0.05895796869994423 276.0517352037008 1.0224410076341484 10.534489466784159 44.02969447224338 0.02999999791666474 1.5228787754397055 2.095482325636716 LVQSPNSYFMDVK ddPTM_PC-9_Lapatinib_30min_R1 2 LVQSPNSYFMDVK 13 0 H0YMV8;Q71UM5;C9JLI6;P42677 H0YMV8;P42677 RPS27L;RPS27 40S ribosomal protein S27;40S ribosomal protein S27-like 0 ; 90.861 0.024883000000000002 9041500.0 40045.0 40273.0 41716.0 34912.0 38508.0 35684.0 44079.0 36753.0 40794.0 41725.0 False True 39473.95095664641 40179.75034286577 38286.27150841672 37479.5449430179 36243.03514964092 34157.87850346681 46361.19493979656 38460.67855342301 36199.35014013585 48937.11065493229 0.8066261049816986 0.8210486848351789 0.7823566000531319 0.7658716348681776 0.7406043116276225 0.6979954077044411 0.9473627339117107 0.7859205016131581 0.7397116351103451 1.0 15.578641303875317 -10.90537631691894 5.908798362364652 1.000047526217958 0.7883427275739094 0.5036550950445169 0.06328076530276176 4.055159412636693e-05 4.237874315584156e-06 0.0627129035145976 0.01520670513512265 1.2434367047816012e-11 10.90537631691894 -0.21170479864404856 LVRLS(ph)SDSFAR ddPTM_PC-9_AZD4547_30min_R2 2 LVRLSSDSFAR 11 1 A0A087WSV0;Q9HB09;Q9HB09-3 A0A087WSV0 BCL2L12 Bcl-2-like protein 12 1 LVRLS(0.762)S(0.237)DS(0.001)FAR;LVRLS(0.773)S(0.226)DS(0.001)FAR 96.37100000000001 0.0027519000000000003 43536000.0 30888.3 36799.1 52708.0 68557.0 56233.0 45615.0 47781.0 52184.0 36238.0 40972.0 True False 40710.13688344783 48693.689429378064 52009.057481204574 52752.242845091445 48426.01860223505 42762.686839044974 52033.41643593799 44120.16186902484 38153.46669865676 39537.58275090621 1.0296566975257166 1.2315798296561768 1.315433414553208 1.33423034932206 1.224809794451208 1.0815705934390956 1.3160495107593642 1.1159043825969255 0.9649923956917239 1.0 15.270937049810223 -8.045251800420733 4.011039843850048 0.9893164835353608 1.222870409009743 0.5000854769851983 0.09403553850109575 0.19308964522067418 6.412432754741774 0.0695011565435459 0.02556289354981776 9.010485654736192e-09 8.045251800420733 0.23355392547438225 LVRLS(ph)SDSFAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 LVRLSSDSFAR 11 1 A0A087WSV0;Q9HB09;Q9HB09-3 A0A087WSV0 BCL2L12 Bcl-2-like protein 12 1 LVRLS(0.482)S(0.482)DS(0.035)FAR;LVRLS(0.892)S(0.082)DS(0.026)FAR;LVRLS(0.778)S(0.089)DS(0.133)FAR;LVRLS(0.942)S(0.04)DS(0.018)FAR 85.287 0.0054475 44636900.0 43545.5 33534.9 39274.399999999994 39831.5 65304.0 41381.6 47467.7 51617.0 46001.100000000006 34878.8 True False 50916.89308717124 36864.02324756681 40210.85064499142 37599.87019046535 52508.149988686455 39211.47604785661 42971.21581961238 50262.108442732184 46673.77906196891 41202.05033957115 1.2357854200830822 0.8947133199379151 0.9759429521975084 0.9125727938435577 1.274406238425876 0.9516874943040696 1.0429387728392268 1.2198933797830833 1.13280234059475 1.0 15.330428511645572 -6.222520147902842 24.99992899372996 1.1039854222904284 0.9948357201339323 0.1286311923511 0.12499922928257905 1073.43061071222 689522.2835222521 0.036327693771211735 0.04689801068583395 5.990731456090956e-07 6.222520147902842 -0.10914970215649611 LVRLS(ph)SDSFAR ddPTM_PC-9_Lapatinib_30min_R1 1 LVRLSSDSFAR 11 1 A0A087WSV0;Q9HB09;Q9HB09-3 A0A087WSV0 BCL2L12 Bcl-2-like protein 12 1 LVRLS(0.874)S(0.081)DS(0.044)FAR 106.54 0.011684 16783000.0 44936.0 39811.0 21524.0 20326.0 23025.0 19825.0 19409.0 19890.0 31268.0 14176.0 True False 44295.204399746865 39718.82007548053 19754.37980504271 21820.841845548297 21670.7147688917 18977.130964332187 20413.90305103364 20814.162012014876 27746.268573362944 16626.302711667337 2.664164436791059 2.3889147674189917 1.1881402707277955 1.312429000239226 1.3033995076779457 1.1413921238794227 1.2278077336284992 1.2518815742124527 1.668817719401457 1.0 14.021179763293011 -5.202568367261471 4.250278004308701 1.266200170151899 2.591871620930422 0.9024373270414638 0.16695786525856984 0.05719593854863052 2.1200241079810698 0.042234588694290254 0.12075059435740958 6.272369476699789e-06 5.202568367261471 1.325671450778523 LVRLSSDS(ph)FARLVELFCS(ph)RDDS(ph)SR ddPTM_PC-9_AZD4547_30min_R2 1 LVRLSSDSFARLVELFCSRDDSSR 24 3 A0A087WSV0;Q9HB09;Q9HB09-3 A0A087WSV0 BCL2L12 Bcl-2-like protein 12 3 LVRLS(0.167)S(0.169)DS(0.665)FARLVELFCS(0.968)RDDS(0.861)S(0.17)R 61.138999999999996 0.0044441 20051000.0 14571.0 13497.0 15595.0 21164.0 18397.0 14481.0 15692.0 21240.0 17573.0 14898.0 True False 19204.27490437215 17859.641301779542 15388.200110408025 16284.966780540495 15842.894105335268 13575.5007808004 17088.55760056799 17957.846046644343 18501.872904009455 14376.425554598274 1.3358170868995802 1.2422866333465739 1.0703773376746026 1.132754920108203 1.102005087785395 0.9442890187998295 1.1886513470034452 1.24911759035267 1.2869591842383703 1.0 13.811417399159762 -5.022926952875033 3.702459530329325 1.126742683324866 1.3259160706818682 0.3303488608071916 0.09908304675063673 0.27667336277422555 8.021024558449781 0.02734738404982685 0.10806529803995787 9.485779980670786e-06 5.022926952875033 0.1991733873570023 LVRLSSDS(ph)FARLVELFCS(ph)RDDS(ph)SR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LVRLSSDSFARLVELFCSRDDSSR 24 3 A0A087WSV0;Q9HB09;Q9HB09-3 A0A087WSV0 BCL2L12 Bcl-2-like protein 12 3 LVRLS(0.151)S(0.171)DS(0.679)FARLVELFCS(0.983)RDDS(0.781)S(0.236)R 58.626000000000005 0.0067021 12092000.0 14515.0 11920.0 13408.0 17541.0 20372.0 20162.0 21200.0 26558.0 20804.0 19110.0 True False 16972.10281568223 13103.338823464406 13727.697570123164 16558.2346386893 16380.252841625637 19104.669226827504 19191.78252529156 25860.880640527004 21108.21914269878 22574.49172532325 0.7518265758623277 0.5804488970516025 0.6081066071013209 0.7334931319899828 0.7256089324594123 0.8462945460427167 0.8501534722822979 1.1455797523678994 0.935047371145032 1.0 14.462405884703617 -7.052781661332036 1.048779915885835 1.0299136862734202 0.651012020466333 0.7836957902650419 0.07733682870701261 0.21946194782411996 0.4920167966545499 0.048460955670667626 0.033108149973541647 8.855607077039758e-08 7.052781661332036 -0.3789016658070872 LVS(ph)LIGSK ddPTM_PC-9_AZD4547_30min_R2 2 LVSLIGSK 8 0 P25786;P25786-2;F5GX11 P25786 PSMA1 Proteasome subunit alpha type-1 1 LVS(1)LIGSK;LVS(0.988)LIGS(0.012)K 81.017 0.01848 6664900.0 39615.0 44994.0 42562.0 73054.0 52959.0 58123.0 46051.0 51519.0 48700.0 49432.0 True False 52211.74595681163 59537.43059437423 41997.600070483226 56212.52897304884 45606.556988881384 54488.559621743094 50149.44978739207 43557.92233884507 51274.1825769795 47701.40072592977 1.0945537271912877 1.2481275117359514 0.8804269776433201 1.1784251220633977 0.9560842301238827 1.1422842682295475 1.0513202762226554 0.9131371757636382 1.0748988875940413 1.0 15.541744010364766 -1.522878825332503 0.30270832366489103 1.0066834363878248 2.2711686331846512 0.1171144653891747 0.10527229476081319 108.82932021055842 1.552031171237709 0.10122792144416372 74.74639775238796 0.029999994470192828 1.522878825332503 1.2644851967968265 LVS(ph)LIGSK ddPTM_PC-9_Lapatinib_30min_R1 2 LVSLIGSK 8 0 P25786;P25786-2;F5GX11 P25786 PSMA1 Proteasome subunit alpha type-1 1 LVS(1)LIGSK;LVS(0.998)LIGS(0.002)K 85.355 0.013288 4810500.0 46705.0 42388.0 44609.0 42606.0 42252.0 41451.0 37116.0 39556.0 44395.0 33842.0 True False 46038.97813535197 42289.85319031093 40941.420215719685 45739.38736944948 39766.82043062813 39678.23735700044 39037.68487001725 41393.91616627756 39394.76759992478 39691.54460836952 1.1599190353918352 1.0654625212391842 1.0314897195279875 1.1523710609086422 1.0018965203546837 0.9996647333455934 0.9835264728343579 1.042890030476392 0.9925229161179543 1.0 15.27654408589009 -6.286767451307559 24.445440663214313 1.0043791484247266 1.094619945149919 0.61502347944331 0.038132405566270455 419.11208311167616 404505.3961663799 0.011761407968237849 0.013342420527064417 5.166929652560912e-07 6.286767451307559 0.09024079672519236 LVS(ph)PETEASEESLQFNLEKPATGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LVSPETEASEESLQFNLEKPATGER 25 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 LVS(0.481)PET(0.481)EAS(0.036)EES(0.003)LQFNLEKPATGER;LVS(0.458)PET(0.228)EAS(0.249)EES(0.065)LQFNLEKPATGER 75.225 8.0271e-05 7669400.0 15221.8 17265.8 15857.6 21707.3 18525.8 20366.2 19831.0 15971.0 15591.1 15947.4 True False 17798.550095745893 18979.834518303003 16235.705324282904 20491.110357016147 14895.802478568035 19298.160619353963 17952.464115993258 15551.778172673276 15819.090342036676 18838.53738045106 0.9447946906013854 1.0075004303677295 0.8618347059751496 1.0877229979796614 0.7907090756432906 1.0243980320563453 0.9529648588654611 0.8255300217102582 0.8397196673268438 1.0 14.201399338349285 -7.734820223467135 23.887379688492604 0.8744686659115923 0.9531515765979125 0.09197442571398118 0.08960811074143547 244.12467873408804 219071.63666823233 0.03941308808929522 0.022744066387691227 1.8415341481812268e-08 7.734820223467135 0.07868291068632016 LVS(ph)PETEASEESLQFNLEKPATGER ddPTM_PC-9_Lapatinib_30min_R1 1 LVSPETEASEESLQFNLEKPATGER 25 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 LVS(0.707)PET(0.078)EAS(0.187)EES(0.028)LQFNLEKPATGER 60.635 0.0014432 3139300.0 5027.7 5135.8 6776.5 4835.5 6562.0 6455.3 7004.2 7565.9 7615.0 5851.4 True False 4956.004076032742 5123.908370642609 6219.362328046462 5191.11880075513 6176.0360613883795 6179.221867039274 7366.843204186187 7917.439334675889 6757.318510495038 6862.806693499593 0.7221541123585832 0.746619947126872 0.90624180540265 0.7564133790439012 0.899928606067002 0.9003928192953757 1.0734446609379242 1.1536736627268311 0.9846290027220972 1.0 12.744583003141173 -6.874331097744844 1.4236497401754231 1.0671395031911124 0.788228422324255 0.7424596200262423 0.06909006192019157 0.2019521370159251 0.8475588668007434 0.0337430459032533 0.027682927768501515 1.3355769102109403e-07 6.874331097744844 -0.27891108086685734 LVS(ph)PGSANETSSILVESVTR ddPTM_PC-9_AZD4547_30min_R2 7 LVSPGSANETSSILVESVTR 20 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;A0A0A0MT44 O75369-2 FLNB Filamin-B 1 LVS(0.5)PGS(0.5)ANETSSILVESVTR;LVS(0.968)PGS(0.029)ANET(0.001)S(0.001)SILVESVTR;LVS(0.993)PGS(0.007)ANETSSILVESVTR;LVS(0.999)PGS(0.001)ANETSSILVESVTR;LVS(0.997)PGS(0.003)ANETSSILVESVTR;LVS(0.971)PGS(0.029)ANETSSILVESVTR;LVS(0.5)PGS(0.5)ANETSSILVESVTR 209.85 1.8359000000000003e-21 250017000.0 81357.5 85308.98 113689.00000000001 150222.80000000002 137910.8 128144.8 106996.8 135570.4 121054.59999999999 115797.6 True False 107227.49265887399 112883.43947697167 112181.40957692714 115591.2543791239 118764.26593368895 120131.88539848838 116519.30791973295 114621.10977787129 127453.29901813605 111743.56127004605 0.9595854243426316 1.010200840155532 1.0039183314179774 1.034433242196204 1.062828717680442 1.0750676283546272 1.0427384503895087 1.025751358513366 1.1405874089704813 1.0 16.769832179300515 -5.275657803323986 0.8445114825148596 1.0603450092880393 0.9507076917008824 0.42548667816841057 0.035684941729656056 1.253038438086318 1.1207302322373145 0.013699908834573591 0.11177903721881471 5.300809497606954e-06 5.275657803323986 -0.10963731758715689 LVS(ph)PGSANETSSILVESVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 LVSPGSANETSSILVESVTR 20 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;A0A0A0MT44 O75369-2 FLNB Filamin-B 1 LVS(0.62)PGS(0.379)ANETSSILVESVTR;LVS(0.99)PGS(0.01)ANETSSILVESVTR;LVS(0.993)PGS(0.007)ANETSSILVESVTR;LVS(0.965)PGS(0.035)ANETSSILVESVTR;LVS(0.998)PGS(0.002)ANETSSILVESVTR;LVS(0.966)PGS(0.031)ANET(0.001)S(0.001)S(0.001)ILVESVTR 176.46 2.2984000000000003e-09 183253000.0 97531.1 91883.09999999999 95298.2 110165.4 111691.1 92415.20000000001 97931.7 97544.6 83144.3 72228.2 True False 114041.18890296826 101004.64693374693 97570.47050843605 103993.18979904595 89806.03073626988 87568.78422433841 88654.90041189139 94984.15760704667 84360.12809393821 85322.60090188323 1.3365882860756906 1.1837970932214934 1.1435477760533492 1.2188234852173925 1.052546802218821 1.0263257718202727 1.0390552968941973 1.1132356093583429 0.988719603038686 1.0 16.38064032379166 -1.5228787500057768 0.29897085710291105 1.0089532223051323 3.6430994786912008 0.7929425872306095 0.048137170442541385 25.08521640806074 0.35736373100171054 0.05085380962786721 35.29765479567868 0.029999999673578224 1.5228787500057768 2.6341462563860683 LVS(ph)PGSANETSSILVESVTR ddPTM_PC-9_Lapatinib_30min_R1 7 LVSPGSANETSSILVESVTR 20 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;A0A0A0MT44 O75369-2 FLNB Filamin-B 1 LVS(0.986)PGS(0.004)ANET(0.002)S(0.002)S(0.002)ILVESVT(0.002)R;LVS(0.935)PGS(0.065)ANETSSILVESVTR;LVS(0.975)PGS(0.023)ANET(0.001)SSILVESVTR;LVS(0.865)PGS(0.135)ANETSSILVESVTR;LVS(0.977)PGS(0.023)ANETSSILVESVTR;LVS(0.875)PGS(0.125)ANETSSILVESVTR;LVS(1)PGSANETSSILVESVTR 152.0 8.3048e-06 212475400.0 66361.19999999998 76042.1 85577.6 67597.20000000001 93458.8 85407.8 74839.2 68984.1 91887.45 76926.3 True False 65414.877118846285 75866.0291894628 78541.74006708885 72568.52358564874 87961.73713107048 81755.10748930593 78714.00758498201 72189.35312483856 81538.11776325511 90222.90845714838 0.7250362268017025 0.840873238147666 0.8705299065413354 0.8043248087054893 0.9749379468613356 0.906145777024421 0.8724392610593732 0.8001222124104443 0.9037407367773104 1.0 16.46120617357692 -3.7514069539372326 0.8571647142939393 0.8905615773797151 6.121710654615027e-10 0.43197037749234823 0.05906725882565398 11.829157208671813 1.7821681651561327 0.020448038910500035 15.019511297770132 0.0001772527762285748 3.7514069539372326 -0.890561576767544 LVS(ph)SDPEINTK ddPTM_PC-9_AZD4547_30min_R2 1 LVSSDPEINTK 11 0 Q9Y266 Q9Y266 NUDC Nuclear migration protein nudC 1 LVS(0.5)S(0.5)DPEINTK 155.47 1.1374e-11 0.0 28203.0 30887.0 36586.0 40175.0 36636.0 34009.0 31062.0 39847.0 34478.0 32325.0 True False 37170.96734115761 40870.618721794846 36100.84573513229 30913.27444756254 31549.723783391993 31882.411853756035 33826.4578249326 33689.56174296783 36300.43669176795 31193.31158896424 1.1916326112136224 1.3102366064991415 1.1573264875122866 0.9910225260757254 1.0114259171685334 1.0220912827041932 1.0844138086608262 1.0800251729247858 1.1637250052222907 1.0 14.928949101846744 -5.534816089219414 5.095654670068712 1.0529173047355662 1.2487138870829195 0.6834797874393236 0.05522732181822981 0.09713263351621396 7.336396913009629 0.015519950142871792 0.02925491725256149 2.9186627190896102e-06 5.534816089219414 0.1957965823473533 LVSDGNINSDR ddPTM_PC-9_Lapatinib_30min_R1 1 LVSDGNINSDR 11 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 95.48299999999999 0.028567000000000002 4294900.0 15665.0 18186.0 13547.0 21112.0 18182.0 14140.0 14812.0 11880.0 16570.0 13958.0 False True 15441.614227390823 18143.89143434452 12433.217952932251 22664.646907567443 17112.57050718736 13535.26516194992 15578.892884327384 12431.98817007224 14703.712110164515 16370.621702134076 0.9432515458699929 1.1083202436947939 0.7594835540858815 1.384470750100644 1.0453219687409039 0.8268021464441672 0.9516372174366792 0.7594084327568088 0.8981767691967213 1.0 13.998821491193793 -6.748683192811287 23.12921516947956 0.8761949798249791 1.054156734937411 0.20455373334494031 0.1577442559826333 140.11218039541453 254046.36821926435 0.051378696827678816 0.05098224897980898 1.783679443456607e-07 6.748683192811287 0.17796175511243195 LVSFHDDS(ph)DEDLLHI ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LVSFHDDSDEDLLHI 15 0 P11717 P11717 IGF2R Cation-independent mannose-6-phosphate receptor 1 LVSFHDDS(1)DEDLLHI;LVSFHDDS(1)DEDLLHI 131.96 5.5111e-05 0.0 2430.3 2293.79 6670.9 9637.7 8729.1 8317.9 6988.9 6779.1 6811.4 5462.5 True False 2841.701789387013 2521.5023120700007 6829.959555529134 9097.730914844979 7018.695517368661 7881.694681173918 6326.86079674576 6601.155808050175 6911.0038390972095 6452.808008873791 0.44038220035047587 0.39076047336329767 1.058447662806129 1.409887122371212 1.087696318829984 1.2214364150204293 0.9804817976987956 1.0229896502379088 1.0710072002131965 1.0 12.65571138611412 -5.282067628095584 5.775111675910612 1.1193996531528154 0.4112563187637139 0.841122125378167 0.120135294140439 0.05659840760592741 6.921715560578331 0.032760714794261604 0.07454183344477948 5.223148480879695e-06 5.282067628095584 -0.7081433343891015 down LVSGGGACSDTGACT(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 2 LVSGGGACSDTGACTPAR 18 0 Q9UJC3-2;Q9UJC3 Q9UJC3-2 HOOK1 Protein Hook homolog 1 1 LVSGGGACS(0.021)DT(0.023)GACT(0.956)PAR;LVSGGGACS(0.001)DT(0.002)GACT(0.998)PAR 117.3 0.00027248 10713000.0 22937.0 18329.4 23746.0 32277.0 33126.0 30721.0 27305.0 32702.0 23573.0 29663.0 True False 30230.488880762034 24254.020099047055 23431.112524639222 24836.036324678942 28527.02669638179 28800.011013532836 29735.092103206025 27648.657317201654 24819.020654766686 28624.507398714522 1.0561051220786994 0.8473165934773872 0.8185682358918593 0.8676493879435034 0.9965945020127364 1.0061312361597599 1.0387983866070434 0.9659085807863826 0.8670549438304488 1.0 14.80496324552596 -6.263560772533446 24.861275050508244 0.9817150598034157 0.8882002015382571 0.2279102193373711 0.07276101983862597 248.03069432087565 2906749.6883963873 0.022934171057864727 0.027289932428745 5.450536188574601e-07 6.263560772533446 -0.0935148582651586 LVSGGGACSDTGACT(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LVSGGGACSDTGACTPAR 18 0 Q9UJC3-2;Q9UJC3 Q9UJC3-2 HOOK1 Protein Hook homolog 1 1 LVS(0.001)GGGACS(0.024)DT(0.044)GACT(0.931)PAR 123.58 0.00014576 0.0 7782.8 8380.2 8350.2 8519.9 8158.6 5619.8 7475.4 4643.1 5211.3 4102.8 True False 9100.27432269319 9212.130873187625 8549.300436309852 8042.557624888484 6559.980897000143 5325.087794907514 6767.275994790779 4521.223544771104 5287.505403689005 4846.605162253072 1.877659520022194 1.9007388810903514 1.763977082947579 1.6594208431762758 1.3535208001038326 1.0987253173377973 1.396291995786352 0.9328640137603645 1.0909709428921106 1.0 12.242758840105987 -6.263003567081281 0.8206101702166687 1.050207316288213 1.9465429141616144 0.9020356277826633 0.11042838335794701 0.18826489055442155 0.2728787223072179 0.05892114365428368 0.09956520101033273 5.457533785230218e-07 6.263003567081281 0.8963355978734013 LVSGGGACSDTGACT(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 2 LVSGGGACSDTGACTPAR 18 0 Q9UJC3-2;Q9UJC3 Q9UJC3-2 HOOK1 Protein Hook homolog 1 1 LVSGGGACS(0.006)DT(0.006)GACT(0.987)PAR;LVSGGGACS(0.11)DT(0.349)GACT(0.54)PAR 130.95 0.00010034 9532400.0 35922.0 50029.0 65920.0 51934.0 48351.0 44656.0 39218.0 31746.0 52816.0 31739.0 True False 35409.745692711986 49913.160924272575 60500.31205855868 55753.39960674529 45507.089241723465 42746.16697822034 41248.51614485223 33221.035054470834 46867.30590286357 37225.04386044086 0.9512344921732114 1.3408489486647832 1.6252583149499655 1.497738990335873 1.222485846150579 1.1483174375422776 1.1080850918402039 0.8924377679451145 1.2590262103806293 1.0 15.183985928214534 -6.689953892476393 2.341163236743055 1.0656778710234334 1.3700693165298636 0.32509224887979915 0.18383012587827025 0.3511763356084993 3.9395818257238515 0.07256878735136764 0.07010332930235388 2.041954720340904e-07 6.689953892476393 0.30439144550643027 LVSIGAEEIVDGNAK ddPTM_PC-9_Lapatinib_30min_R1 4 LVSIGAEEIVDGNAK 15 0 O43707 O43707 ACTN4 Alpha-actinin-4 0 ;;; 241.35 5.705199999999999e-32 12931800.0 68416.0 58585.6 67517.4 62424.0 68902.3 54391.0 66449.0 64468.7 62536.0 69697.0 False True 67440.37529404224 58449.94864268856 61966.379996701005 67014.86920035961 64849.60218113387 52064.823721613735 69889.40408254587 67464.1511565603 55492.53714672589 81744.0335845853 0.82501893210662 0.7150362672305253 0.7580538576259611 0.819813584694416 0.7933252047567512 0.6369250627660701 0.854978657374758 0.8253097895732198 0.6788573393470306 1.0 16.318825813131944 -11.568220080318923 2.7883355475018226 1.3098842807870676 0.7683940737901076 0.5169391255365378 0.06742632602342517 7158043.240827069 8223864.191943776 14028926.501744589 0.016491658330918226 2.702588470435613e-12 11.568220080318923 -0.54149020699696 LVSPET(ph)EASEESLQFNLEKPATGER ddPTM_PC-9_AZD4547_30min_R2 1 LVSPETEASEESLQFNLEKPATGER 25 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 LVS(0.155)PET(0.747)EAS(0.097)EESLQFNLEKPATGER 126.09 5.8857e-08 5400500.0 10366.0 7845.3 11174.0 12357.0 14811.0 12738.0 7927.1 13241.0 9746.3 12987.0 True False 13662.17237380561 10381.139801796779 11025.825459038108 9508.284563746865 12754.748306469566 11941.490846339035 8632.59654317247 11194.907697910441 10261.469520534196 12532.329082935146 1.0901542948157126 0.8283488035701544 0.8797906108331934 0.7587005177428654 1.0177476366972584 0.9528548737679865 0.688826193921702 0.893282296038186 0.8187998777104326 1.0 13.613366938195275 LVSPET(ph)EASEESLQFNLEKPATGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LVSPETEASEESLQFNLEKPATGER 25 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 LVS(0.008)PET(0.83)EAS(0.161)EESLQFNLEKPATGER 99.92299999999999 1.1825e-06 3359800.0 6589.6 10805.0 10327.0 8051.1 11720.0 10789.0 10132.0 8749.9 6322.4 6802.4 True False 7705.089129467415 11877.648992242697 10573.234845365598 7600.022969018377 9423.550132723956 10223.205847050987 9172.223610672363 8520.224396285379 6414.853139194326 8035.621272231232 0.9588666350035634 1.478124539453893 1.3157955666606165 0.9457915836927063 1.1727220352319245 1.2722358982222584 1.1414454837946255 1.0603068646015952 0.7983020754552222 1.0 12.97219385451358 -7.940559085402952 2.7137055034181494 0.9014750193388084 1.1955695957633707 0.34173774053359507 0.15615833830650888 0.31041792857712974 4.44719604771151 0.1143866603592664 0.04330779460339702 1.1466765064251413e-08 7.940559085402952 0.2940945764245624 LVSPETEAS(ph)EESLQFNLEKPATGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LVSPETEASEESLQFNLEKPATGER 25 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 LVS(0.003)PET(0.087)EAS(0.849)EES(0.06)LQFNLEKPATGER 71.042 0.0001989 6274400.0 6576.4 7721.2 5744.3 5671.8 6001.3 4929.2 7061.8 5212.6 5891.6 5122.1 True False 7689.654630179303 8487.7097083669 5881.265897379066 5354.027434223702 4825.388345692512 4670.70407463933 6392.855180995466 5075.774773206226 5977.753504187855 6050.696183478707 1.2708710530163019 1.4027658059484798 0.9719982162445593 0.8848613898087886 0.797493081683415 0.7719283753483748 1.0565486990490478 0.8388745062205433 0.9879447460128603 1.0 12.562885430796237 -5.345913470752797 4.4399525754516285 0.8975094889656553 1.3368408010265052 0.7741488003642192 0.09165255090266361 0.08926339223023878 3.132012425474358 0.024283100787831143 0.05427042042425694 4.509065346406957e-06 5.345913470752797 0.43933131206084985 LVSPETEAS(ph)EESLQFNLEKPATGER ddPTM_PC-9_Lapatinib_30min_R1 1 LVSPETEASEESLQFNLEKPATGER 25 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 LVS(0.003)PET(0.273)EAS(0.595)EES(0.129)LQFNLEKPATGER 56.29 0.0026896999999999997 6867300.0 11910.0 8254.9 16817.0 14545.0 14991.0 26448.0 21186.0 15485.0 28406.0 12686.0 True False 11740.161215973498 8235.786286229539 15434.371175497272 15614.687820697627 14109.258853439973 25316.880693299263 22282.907416105863 16204.489630771777 25206.617151559043 14878.758196967538 0.7890551792397754 0.5535264554476117 1.0373426983068368 1.049461763810375 0.9482820183417997 1.7015452740175008 1.4976322029782954 1.0891022904098568 1.6941344712958937 1.0 13.860966501570863 -5.964104566594164 1.0320939949509533 1.3887115576500282 0.6767689710987206 0.5033636238708632 0.25359650523075133 0.4513411233177867 0.9701855820491231 0.10230043867698928 0.22580762126885467 1.086164072626411e-06 5.964104566594164 -0.7119425865513076 LVSPGS(ph)ANETSSILVESVTR ddPTM_PC-9_AZD4547_30min_R2 2 LVSPGSANETSSILVESVTR 20 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;A0A0A0MT44 O75369-2 FLNB Filamin-B 1 LVS(0.026)PGS(0.963)ANET(0.004)S(0.004)S(0.004)ILVESVTR;LVS(0.081)PGS(0.918)ANETSSILVESVTR 117.55 1.6118e-05 5912400.0 16012.5 15752.1 23075.4 29445.2 28730.4 24773.9 21082.5 25815.7 19991.6 24049.2 True False 21104.141919309517 20843.65827589551 22769.405118801482 22657.064063805075 24741.679882802873 23224.784116668132 22958.80165778579 21826.476750770074 21048.315162339695 23207.24482800678 0.909377311943587 0.8981530737651862 0.981133490319501 0.976292715129297 1.0661187946336619 1.0007557678126524 0.9892945857182854 0.9405027142398921 0.9069717374178919 1.0 14.502287635152516 -5.265883852620178 21.055686665773823 0.9841490968626236 0.9037651488572862 0.39418026868029854 0.03907390479291648 41.62815983068431 197228.87955440747 0.011205788992378792 0.024847282497892427 5.4214586208459554e-06 5.265883852620178 -0.08038394800533744 LVSPGS(ph)ANETSSILVESVTR ddPTM_PC-9_Lapatinib_30min_R1 1 LVSPGSANETSSILVESVTR 20 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;A0A0A0MT44 O75369-2 FLNB Filamin-B 1 LVS(0.007)PGS(0.951)ANET(0.011)S(0.03)S(0.001)ILVESVTR 77.554 0.0019507 2428700.0 7631.0 5245.0 7576.7 5894.2 4860.3 8688.2 5826.8 5527.2 9002.3 5797.6 True False 7522.180540645991 5232.855524751839 6953.772972907785 6327.679130474798 4574.426709717451 8316.625939183405 6128.483193248638 5784.0138900356305 7988.366175578399 6799.707435183592 1.1062506162727122 0.7695706873615735 1.0226576715531928 0.9305810861410908 0.6727387543246471 1.2230858486867908 0.9012863055751705 0.8506268755193086 1.174810277019325 1.0 12.731256958835372 -6.767227292305829 24.99989006782968 1.0125837465019087 0.9015670024364892 0.14608304473618205 0.15381473760194445 333.6841817918747 1441282.2572566832 0.052237104485249944 0.04730433148554643 1.7091205958389689e-07 6.767227292305829 -0.1110167440654195 LVSPGSANETSSILVESVTR ddPTM_PC-9_Lapatinib_30min_R1 2 LVSPGSANETSSILVESVTR 20 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;A0A0A0MT44 O75369-2 FLNB Filamin-B 0 ; 133.96 0.00019928 10397000.0 52223.0 25717.0 40407.0 35519.0 32980.0 36937.0 32386.0 29928.0 39162.0 33403.0 False True 51478.290443474725 25657.453866547774 37084.892435530615 38131.18574791056 31040.18124117474 35357.290614352474 34062.78861408496 31318.564137535534 34751.163165857746 39176.66404330024 1.314003928118485 0.6549167595839636 0.9466066940907045 0.973313748862482 0.7923130261133873 0.9025089674627125 0.8694662867781917 0.7994188607514031 0.8870373222040758 1.0 15.257706934554411 -4.743434490689787 24.98886097086514 0.8675116572565968 1.3140053323698568 0.658736782935863 0.09596941153912016 686.6561633032953 952955.0457608433 0.02265332587041322 0.7250955022868861 1.8053670395322973e-05 4.743434490689787 0.44649367511326 LVSS(ph)DPEINTK ddPTM_PC-9_AZD4547_30min_R2 1 LVSSDPEINTK 11 0 Q9Y266 Q9Y266 NUDC Nuclear migration protein nudC 1 LVS(0.078)S(0.919)DPEINT(0.003)K 95.01799999999999 0.016250999999999998 0.0 15456.0 16377.0 21059.0 26663.0 20931.0 25110.0 22511.0 24897.0 21668.0 20782.0 True False 20370.686495228598 21670.544980309965 20779.743900293837 20516.257289243582 18025.091945359156 23539.867730536444 24514.435390414594 21049.74072614425 22813.326243901287 20054.428505548483 1.015769982654585 1.0805865135630441 1.0361673430157674 1.023028768113104 0.8988085569415319 1.1737989803111886 1.2223951125624026 1.0496305452095227 1.1375704990840052 1.0 14.291633233562314 -6.7880431164124655 24.998963490620568 1.126388194714047 1.0168257894235808 0.34518079491815035 0.07201604688736335 254.29506453974517 238953.84084623287 0.025585776768743802 0.022570594047826263 1.6291342854482159e-07 6.7880431164124655 -0.10956240529046624 LVSS(ph)DPEINTK ddPTM_PC-9_Lapatinib_30min_R1 2 LVSSDPEINTK 11 0 Q9Y266 Q9Y266 NUDC Nuclear migration protein nudC 1 LVS(0.029)S(0.971)DPEINTK;LVS(0.048)S(0.952)DPEINTK 120.55 0.0018428000000000001 2237200.0 100152.0 92374.0 74981.0 80158.0 80159.0 78372.0 67651.0 73370.0 79797.0 63424.0 True False 98723.8141143728 92160.11367844143 68816.35161502994 86053.08671924913 75444.20521865762 75020.2122540551 71153.63776111478 76779.03805035357 70809.42156033781 74386.7538928321 1.3271692733978249 1.2389317836239384 0.9251156693054874 1.1568334712282853 1.0142155863844922 1.0085157414199795 0.9565363997953825 1.0321600827073056 0.9519090141015146 1.0 16.18275812192448 -5.12000401461119 4.487080596458736 1.0113732752756563 1.3087239288011103 0.7729334715053411 0.06073721747163912 0.09493822030990957 2.9756622641402006 0.015409200847667252 0.04593373872000255 7.585705627827184e-06 5.12000401461119 0.297350653525454 LVT(ph)SPQSEPPAPFPPPR ddPTM_PC-9_AZD4547_30min_R2 1 LVTSPQSEPPAPFPPPR 17 0 Q9H792;H0YN99 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 LVT(0.632)S(0.368)PQS(0.001)EPPAPFPPPR 199.33 4.7517e-12 5601400.0 10430.0 12532.0 12097.0 24434.0 23437.0 21095.0 14937.0 22171.0 18020.0 17713.0 True False 13746.523042522911 16582.72392338307 11936.585875960616 18801.11880153686 20183.177102067864 19775.92631523958 16266.364063196788 18744.98138889602 18972.50041144088 17092.8732614176 0.8042254120933464 0.9701542666213965 0.6983370024104802 1.0999390514393592 1.180794872423571 1.1569691071119228 0.9516459763329301 1.096654793036323 1.1099655465337133 1.0 14.061107309716078 -5.781507580177252 24.998306276216017 1.090582267023964 0.8388304430792733 0.6434603946012529 0.08873331130757768 144.4235632350424 179903.25651568378 0.024906017545786183 0.036994459846156416 1.6538359184620927e-06 5.781507580177252 -0.25175182394469064 LVT(ph)SPQSEPPAPFPPPR ddPTM_PC-9_Lapatinib_30min_R1 2 LVTSPQSEPPAPFPPPR 17 0 Q9H792;H0YN99 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 LVT(0.5)S(0.5)PQS(0.001)EPPAPFPPPR;LVT(0.607)S(0.392)PQS(0.001)EPPAPFPPPR 220.25 3.6289e-24 5062800.0 35430.6 24490.9 29788.3 24788.1 47402.2 46639.5 50315.0 47185.0 52028.0 34729.2 True False 34925.35314682372 24434.192825766404 27339.220960163268 26611.099564677552 44614.0957923109 44644.83730698469 52920.06450681422 49377.387357311316 46168.05876087146 40732.09594624983 0.857440608823845 0.5998756572215146 0.6711960267460867 0.6533201630427666 1.095305673716957 1.0960603983133628 1.299222720496575 1.2122476442771282 1.1334564963657885 1.0 15.313878432374974 -6.323591938417922 4.069560064730045 1.1636344028597674 0.6851207160498808 0.835414408385317 0.09641841334914047 0.08286617448619354 2.7717808737813012 0.030533677461027753 0.03561472475894341 4.74687790783156e-07 6.323591938417922 -0.4785136868098866 LVT(ph)VTYTIVT(ph)PLLNPMVYS(ph)LR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LVTVTYTIVTPLLNPMVYSLR 21 0 A0A126GVZ9;A0A286YEZ2;Q8NGX6 A0A126GVZ9 OR10R2 Olfactory receptor 10R2 3 LVT(0.776)VT(0.106)Y(0.093)T(0.046)IVT(0.977)PLLNPMVY(0.193)S(0.808)LR 46.336999999999996 0.035684 2920600.0 17260.0 13253.0 13913.0 20225.0 18415.0 19273.0 18081.0 18226.0 19674.0 14019.0 True False 20181.777099460913 14568.670253974306 14244.73868534633 19091.858820334703 14806.712943183586 18262.28995182256 16368.236784896078 17747.586812043275 19961.69503044875 16560.533725657053 1.218667069177457 0.8797222659196802 0.8601618112873448 1.1528528691533593 0.8940963611724487 1.1027597452085132 0.9883882401408929 1.0716796394398287 1.2053775174843742 1.0 14.015461549424753 -7.939693217518321 5.139462594574051 1.1139469354554767 1.0074792665181398 0.08077441195539037 0.12145028812772347 0.40896942210005044 21.53690311505667 0.06777134470819945 0.030934720142034168 1.1489649554394092e-08 7.939693217518321 -0.10646766893733695 LVTS(ph)PQSEPPAPFPPPR ddPTM_PC-9_AZD4547_30min_R2 1 LVTSPQSEPPAPFPPPR 17 0 Q9H792;H0YN99 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 LVT(0.013)S(0.987)PQSEPPAPFPPPR 195.2 2.0989e-53 0.0 6134.6 7374.8 9611.0 16644.0 15956.0 13544.0 10421.0 13222.0 9879.8 10465.0 True False 8085.275192393201 9758.559877925753 9483.551860284164 12806.98294723662 13740.784820608224 12697.091538924155 11348.448811848004 11178.843711333871 10402.026057988549 10098.623535298098 0.8006314092343808 0.966325741702945 0.9390935137977913 1.2681909472584942 1.3606591801921857 1.2573091267877778 1.1237619436135375 1.1069670705378847 1.0300439482301678 1.0 13.301871043404837 -5.675074919887133 6.045233104202419 1.1782882345161736 0.9018509559603788 0.5352740657017605 0.11153886991109081 0.16861494612649694 9.37251343214539 0.03294060267422404 0.057420169815440625 2.1131244745245592e-06 5.675074919887133 -0.2764372785557948 LVTS(ph)PQSEPPAPFPPPR ddPTM_PC-9_Lapatinib_30min_R1 1 LVTSPQSEPPAPFPPPR 17 0 Q9H792;H0YN99 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 LVT(0.054)S(0.922)PQS(0.023)EPPAPFPPPR 156.72 2.7523e-05 4821000.0 14185.0 9864.3 10866.0 11446.0 19685.0 22811.0 24222.0 22145.0 19411.0 17333.0 True False 13982.719298789585 9841.459819410788 9972.639423972969 12287.777022736685 18527.167002199058 21835.426705038175 25476.09664084376 23173.93754429711 17224.72877310823 20328.98595522926 0.6878217796787246 0.4841097259393429 0.49056256155303657 0.6044461366542427 0.9113670029091286 1.0741030936381464 1.2531907246603464 1.139945573051864 0.8472989656760269 1.0 14.31125063241784 -6.370314594820441 2.398497504666698 1.0822867041233422 0.5446886516738231 0.8176724987782793 0.11075571627275817 0.12039311354542799 1.3559552156846253 0.03918954445173155 0.04633968628276395 4.2627062444865123e-07 6.370314594820441 -0.5375980524495191 LVTSGAESGNLNT(ph)SPSSNQTR ddPTM_PC-9_AZD4547_30min_R2 1 LVTSGAESGNLNTSPSSNQTR 21 0 Q8NHV4-2;Q8NHV4;Q8NHV4-3 Q8NHV4-2 NEDD1 Protein NEDD1 1 LVTSGAESGNLNT(0.874)S(0.116)PS(0.005)S(0.005)NQTR 159.01 1.9791e-05 32115000.0 15510.0 17279.0 22651.0 30312.0 24961.0 20716.0 19405.0 26434.0 22629.0 21890.0 True False 20441.85737195882 22864.098840738607 22350.63294009952 23324.036715731592 21495.596008222736 19420.625245153045 21132.007407533885 22349.232692890604 23825.1227419809 21123.637762797436 0.9677242907450649 1.0823940032245032 1.0580863576189061 1.1041676143873977 1.017608626392959 0.9193788240090112 1.0003962217507436 1.058020069452794 1.1278891926437629 1.0 14.366570686330073 -11.808356888148156 2.200657850538006 0.844159817967867 1.0366778604044398 0.03345257361667364 0.06005980950182328 18272195.164300606 2325256.800981312 14204029.147243908 0.01782806931978598 1.5546875182212047e-12 11.808356888148156 0.19251804243657278 LVTSGAESGNLNT(ph)SPSSNQTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LVTSGAESGNLNTSPSSNQTR 21 0 Q8NHV4-2;Q8NHV4;Q8NHV4-3 Q8NHV4-2 NEDD1 Protein NEDD1 1 LVTSGAESGNLNT(0.538)S(0.154)PS(0.154)S(0.154)NQTR;LVTSGAESGNLNT(0.676)S(0.023)PS(0.225)S(0.077)NQTR;LVTSGAESGNLNT(0.567)S(0.221)PS(0.029)S(0.183)NQTR 293.08 2.9577999999999996e-131 40107700.0 77059.0 66849.0 77273.0 78164.0 91291.0 70337.0 82693.0 72183.0 68298.0 62875.0 True False 90103.56671537433 73485.32693034987 79115.4813794846 73784.72449110723 73403.18388792679 66648.4038987882 74859.7203945252 70288.27273421055 69296.72904287842 74273.73978177382 1.2131281793553232 0.9893850389957417 1.06518779870162 0.9934160405534529 0.9882790889969343 0.8973346985705866 1.0078894723016918 0.9463408324493541 0.9329909769789628 1.0 16.18056460130641 -1.5228787453096937 0.7494090051635145 0.9632547126938474 41.24737467261849 0.7132796093876621 0.04409792807165335 199.63121045653207 0.8636418642246547 0.016030701426337668 13575.280047953533 0.02999999999797215 1.5228787453096937 40.284119959924645 LVTSGAESGNLNT(ph)SPSSNQTR ddPTM_PC-9_Lapatinib_30min_R1 1 LVTSGAESGNLNTSPSSNQTR 21 0 Q8NHV4-2;Q8NHV4;Q8NHV4-3 Q8NHV4-2 NEDD1 Protein NEDD1 1 LVTSGAESGNLNT(0.94)S(0.042)PS(0.013)S(0.005)NQTR 232.37 6.225299999999999e-42 30887000.0 144230.0 102640.0 112240.0 111760.0 129840.0 110250.0 114050.0 102430.0 143970.0 80093.0 True False 142173.25375145726 102402.3433861827 103012.06045892925 119979.203220431 122203.0664752616 105534.86450530266 119954.95094906425 107189.27173909936 127754.58252868963 93936.96833278585 1.5134962973021133 1.0901176097509022 1.0966083139280536 1.277230949112458 1.3009049434333333 1.123464663362666 1.2769727731057465 1.1410765499623665 1.3600032532037845 1.0 16.519405413193766 -10.79027197762401 3.5102962998177047 0.9993835718697635 1.2307647606259997 0.24030411437211308 0.1277460379148211 19082596.85055289 29200328.006510876 124781.20562379088 0.03148547502128039 1.6207947541171483e-11 10.79027197762401 0.23138118875623626 LVTSGAESGNLNTSPS(ph)SNQTR ddPTM_PC-9_AZD4547_30min_R2 1 LVTSGAESGNLNTSPSSNQTR 21 0 Q8NHV4-2;Q8NHV4;Q8NHV4-3 Q8NHV4-2 NEDD1 Protein NEDD1 1 LVTSGAESGNLNT(0.116)S(0.037)PS(0.424)S(0.424)NQTR 335.42 1.0168999999999997e-209 30613000.0 43517.0 40927.0 57360.0 72999.0 60074.0 51049.0 43226.0 45981.0 39439.0 44462.0 True False 57354.50079016968 54155.85237889397 56599.368921641806 56170.20837330722 51733.76205272112 47856.89796002209 47073.03026014219 38875.692988265226 41523.66502368572 42905.39891317952 1.3367665199018053 1.2622153330512116 1.319166593373773 1.3091641097888282 1.2057634554897412 1.115405034617254 1.097135359477627 0.906079280766774 0.9677958036868557 1.0 15.388871577278797 -7.005920718695378 1.0473539573020247 0.9530529607269139 1.310185841880505 0.924531635218446 0.041086510015188406 0.12554078914737254 0.2835485862211347 0.025679991296236097 0.018328865575263285 9.864595493097195e-08 7.005920718695378 0.3571328811535911 LVTSGAESGNLNTSPS(ph)SNQTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LVTSGAESGNLNTSPSSNQTR 21 0 Q8NHV4-2;Q8NHV4;Q8NHV4-3 Q8NHV4-2 NEDD1 Protein NEDD1 1 LVT(0.101)S(0.01)GAES(0.004)GNLNT(0.044)S(0.149)PS(0.501)S(0.191)NQTR 265.09 1.3489999999999999e-86 22253000.0 15491.0 14044.0 17187.0 16690.0 18562.0 20278.0 16597.0 16973.0 14205.0 13827.0 True False 18113.320338803544 15438.195506437429 17596.803262060468 15754.913409710061 14924.909348431922 19214.58598262117 15024.812008125664 16527.47673438003 14412.721251780229 16333.725645528217 1.1089521602049521 0.9451729410346768 1.077329425260553 0.9645633673309175 0.9137480126904179 1.1763749679413567 0.9198643551502959 1.011862026646986 0.8823903109775869 1.0 13.995566279896602 LVTSGAESGNLNTSPS(ph)SNQTR ddPTM_PC-9_Lapatinib_30min_R1 1 LVTSGAESGNLNTSPSSNQTR 21 0 Q8NHV4-2;Q8NHV4;Q8NHV4-3 Q8NHV4-2 NEDD1 Protein NEDD1 1 LVTSGAESGNLNT(0.013)S(0.126)PS(0.431)S(0.431)NQTR 309.61 4.133499999999999e-149 40150000.0 52435.0 46747.0 50629.0 44128.0 49959.0 49811.0 41652.0 41636.0 50710.0 34400.0 True False 51687.26728459864 46638.76019362713 46466.4790535917 47373.320326692694 47020.50984317311 47680.699645112254 43808.53675519875 43570.56055969089 44998.5058000267 40345.99416488126 1.2811003509634487 1.155970032688483 1.1516999398675853 1.1741765522766148 1.1654319298965647 1.1817951356027163 1.0858212236924236 1.0799228389721134 1.115315330095278 1.0 15.300137819214816 -1.5228787453328687 0.05156459629082539 0.7187676467799675 1.9326720703385845 0.7645044015322352 0.03452279085028287 231.1582919096058 0.901820981808253 4.890604322028975 22.110675316866743 0.029999999996371277 1.5228787453328687 1.213904423558617 LVTSPQS(ph)EPPAPFPPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LVTSPQSEPPAPFPPPR 17 0 Q9H792;H0YN99 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 LVT(0.091)S(0.381)PQS(0.528)EPPAPFPPPR 99.238 0.0012772999999999999 4507100.0 15026.0 16209.0 15875.0 18539.0 25018.0 21294.0 28933.0 23946.0 23164.0 23612.0 True False 17569.605022972177 17818.122398450894 16253.520206272759 17500.319934248957 20115.90249321569 20177.305154055404 26192.25678321984 23317.44287288423 23502.729678017404 27892.668687510857 0.6299004666713406 0.6388102407149405 0.5827165693023267 0.6274164774374871 0.721189597115271 0.7233909877935035 0.9390373175352565 0.8359703094069583 0.8426131590822258 1.0 14.767598353286365 -6.9062910257005194 1.2426698880087426 0.9000948193276034 0.6165263215946699 0.8466471213330331 0.05331704629793458 0.1699943117828753 0.5452272083373524 0.02804720091259028 0.022102014940771554 1.2408205408962852e-07 6.9062910257005194 -0.28356849773293347 LVVECVMNNVTCTR ddPTM_PC-9_Lapatinib_30min_R1 1 LVVECVMNNVTCTR 14 0 I6L8B7;Q01469 I6L8B7 FABP5 Fatty acid-binding protein, epidermal 0 101.72 0.007555 3410800.0 9053.7 7917.1 9490.1 6840.2 6800.3 10566.0 8062.3 7085.7 8171.4 6700.5 False True 8924.592577754758 7898.76844137517 8709.86061084538 7343.25112623829 6400.319723904206 10114.116810548998 8479.726444863132 7414.927489619605 7251.050883343293 7858.672497144967 1.1356361498709913 1.0051021268852685 1.1083119463254956 0.9344136848693049 0.8144275927301238 1.2870006752697007 1.0790278444538557 0.94353435549241 0.9226813925605857 1.0 12.940069914762406 -2.32201961369859 1.2495988517822683 1.0104691309286427 69.7627439750417 0.08506438008665107 0.12151167756006459 2505.6430204180956 9.377828615673913 0.03736367480871185 491681.46145398746 0.004764094706150062 2.32201961369859 68.75227484411306 LVVPATQCGSLIGK ddPTM_PC-9_Lapatinib_30min_R1 2 LVVPATQCGSLIGK 14 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 0 ; 179.35 0.00028086 12254800.0 90723.0 88847.0 98931.0 96025.0 97263.0 86723.0 98268.0 72528.0 82105.0 80592.0 False True 89429.27338343918 88641.28023024321 90797.27506470344 103086.99883000969 91542.18156641537 83014.05945118688 103355.83621098312 75897.91565648139 72857.47029602033 94522.21981791024 0.9461190559819456 0.9377824642819835 0.9605918612535485 1.0906112766775773 0.9684726167324923 0.8782491525390227 1.0934554479368994 0.8029637454843196 0.7707972838172297 1.0 16.52836589039618 -7.783084761428975 24.999159610853532 0.8401603332946193 0.9792905260485254 0.3077829437372568 0.08406474753770514 266.52069939701397 307811.5203669189 0.04458173309015976 0.02144591625409508 1.6478407503960802e-08 7.783084761428975 0.13913019275390615 LVVSS(ph)PTSPK ddPTM_PC-9_Lapatinib_30min_R1 1 LVVSSPTSPK 10 0 Q9Y4G2 Q9Y4G2 PLEKHM1 Pleckstrin homology domain-containing family M member 1 1 LVVS(0.146)S(0.685)PT(0.146)S(0.023)PK 70.41199999999999 0.035844 10499000.0 110600.0 82413.0 76281.0 82099.0 87403.0 79423.0 91774.0 104130.0 91529.0 77008.0 True False 109022.823718444 82222.17776193951 70009.47063317508 88136.83433423538 82262.12738090949 76026.26343405584 96525.60866636925 108968.2599452543 81220.04017690087 90318.7301932899 1.2070898636985452 0.9103557765479756 0.7751378975695158 0.9758422660019126 0.9107980947568839 0.8417552291905904 1.0687219412827893 1.2064857390272516 0.8992602088523938 1.0 16.462737582702864 -7.286945282376481 23.62011993697013 1.060824168094494 0.9288668809677031 0.13696838046037785 0.12750963374633548 663.6267321582648 614557.2287565693 0.05325266195935424 0.035923111985826595 5.1648143769409316e-08 7.286945282376481 -0.131957287126791 LVVSSPT(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 1 LVVSSPTSPK 10 0 Q9Y4G2 Q9Y4G2 PLEKHM1 Pleckstrin homology domain-containing family M member 1 1 LVVS(0.022)S(0.035)PT(0.695)S(0.248)PK 105.17 0.0055842 0.0 162200.0 147440.0 139080.0 149510.0 136360.0 120050.0 146180.0 156560.0 129230.0 146380.0 True False 213776.22603041347 195097.09665365441 137235.7083267423 115042.77940647356 117428.76774493205 112543.25452213848 159189.7368118165 132367.24939089658 136060.83397172618 141255.2807546042 1.5134034273861683 1.3811667472636788 0.971543913923863 0.8144317068494712 0.8313230281913158 0.7967366170023357 1.1269648537131078 0.9370782365358195 0.9632265303277258 1.0 17.107945277370447 -5.220556523912557 3.1757084071158896 0.9180818788150057 1.4890861164824587 0.8338044950832253 0.09332321129338635 0.09805944134864523 1.9803271927538146 0.026646153802887478 0.08241613700963558 6.017879344296784e-06 5.220556523912557 0.571004237667453 LVYLLTDKT(ph)GT(ph)LT(ph)QNEMIFK ddPTM_PC-9_Lapatinib_30min_R1 1 LVYLLTDKTGTLTQNEMIFK 20 1 O43861-2;O43861 O43861-2 ATP9B Probable phospholipid-transporting ATPase IIB 3 LVY(0.267)LLT(0.238)DKT(0.807)GT(0.763)LT(0.924)QNEMIFK 43.888000000000005 0.029192000000000003 4344700.0 7616.9 7119.6 10381.0 8177.5 8939.6 8268.6 5482.3 7229.0 9344.8 5217.6 True False 7508.281609231613 7103.115003626925 9527.514251818826 8778.900629340309 8413.790303929823 7914.971253048027 5766.14666890008 7564.885730761972 8292.290218893502 6119.455207985011 1.2269526214415922 1.1607430338501994 1.556921969031947 1.434588591789201 1.374924730709857 1.293411093641167 0.9422647070569429 1.236202484314434 1.3550700082048568 1.0 12.579187505599096 -7.015898579042508 23.8399518301053 1.1480349672678263 1.3541491494853592 0.3277264099256936 0.1471382336689359 518.8757432996331 778054.0599348316 0.05784536639810867 0.0462450091646072 9.640541332707236e-08 7.015898579042508 0.20611418221753297 LWCTYHEK ddPTM_PC-9_AZD4547_30min_R2 2 LWCTYHEK 8 0 P15121;E9PCX2 P15121 AKR1B1 Aldose reductase 0 ; 128.38 0.0031006000000000002 11435300.0 66506.0 46255.0 103647.0 100761.0 92687.0 68812.0 108545.0 152221.0 78847.0 83129.0 False True 87653.5245892647 61206.02418417522 102272.57305825336 77532.10819193165 79819.00994407838 64509.1747619941 118205.29472047235 128698.74214059561 83014.69145065926 80218.67901249853 1.0926822239943366 0.7629896794316318 1.2749221791886989 0.966509410854942 0.9950177555484568 0.8041665053091089 1.4735382852920738 1.6043488090915037 1.0348548800925168 1.0 16.291650588561396 -7.265172055183706 24.997232054593898 1.3285478953000007 0.9858319216616293 0.2980670700991612 0.21665563012026262 358.2705591043282 2399275.3897549524 0.08578657505485351 0.060360634869749456 5.430351537109306e-08 7.265172055183706 -0.3427159736383715 LWNPQEK ddPTM_PC-9_AZD4547_30min_R2 1 LWNPQEK 7 0 Q13033-2;Q13033 Q13033-2 STRN3 Striatin-3 0 73.975 0.029289999999999997 46171000.0 413400.0 274190.0 325400.0 472760.0 398530.0 319180.0 233600.0 196110.0 161440.0 198310.0 False True 544852.6007458263 362816.55542231153 321084.9833874167 363772.4860691889 343200.98862854013 299221.62414307595 254389.9474568371 165805.70565948327 169973.38881370804 191367.22726086577 2.8471573139485393 1.8959179197790823 1.6778472886045623 1.900913188094144 1.7934156936950305 1.5635990991037692 1.3293287001021379 0.8664268591479468 0.8882053173190709 1.0 17.545984255584827 -1.5228787452803412 0.20309050229125694 0.7451420276139236 9.72776044365979 0.8258364851167167 0.23794089336362112 22.9970094760593 0.28052392120827085 0.4698385750879274 66.03639001642911 0.02999999999999975 1.5228787452803412 8.982618416045867 up LWNPQEK ddPTM_PC-9_Lapatinib_30min_R1 1 LWNPQEK 7 0 Q13033-2;Q13033 Q13033-2 STRN3 Striatin-3 0 85.359 0.016229 33865000.0 485390.0 360510.0 487710.0 288360.0 265890.0 347380.0 360970.0 371460.0 397460.0 215610.0 False True 478468.2495903764 359675.26124466903 447612.36641504336 309566.9563407616 250250.87295985318 332523.367182331 379659.26036022557 388719.38768139994 352693.86936065083 252877.90121773435 1.892091983072902 1.422327769696963 1.7700730837276193 1.2241755995681747 0.9896114755570545 1.3149562123897092 1.501354046881816 1.5371821175734237 1.3947200117616145 1.0 17.948081441067835 -5.763857440754013 24.9981978586969 1.3012125716714902 1.6675806575927532 0.458777003857469 0.20481427453243317 66.2637090406174 685053.7056185384 0.06002389268534859 0.09399815778233334 1.7224338793784158e-06 5.763857440754013 0.366368085921263 LWPTFFER ddPTM_PC-9_Lapatinib_30min_R1 1 LWPTFFER 8 0 O60218 O60218 AKR1B10 Aldo-keto reductase family 1 member B10 0 113.89 0.017054 3261500.0 10865.0 11780.0 11201.0 8493.9 10390.0 11873.0 13161.0 12596.0 10838.0 10464.0 False True 10710.06310760303 11752.724133761047 10280.097017110367 9118.569740819772 9778.880627525938 11365.219467314808 13842.412182732422 13181.256143958748 9617.31031080043 12272.688457596438 0.8726745687880484 0.9576324025797666 0.8376401839441533 0.7429969213612395 0.7968002008128133 0.9260578484154437 1.1279038191639559 1.0740316752520458 0.783635170405356 1.0 13.583163700236076 -6.997277287617632 8.451791316639534 1.0061056736069796 0.8439956717405922 0.3580503164989466 0.09756418122975348 0.1281637231145863 96.30629911306748 0.03696880688924513 0.03140882292006175 1.0062889699930679e-07 6.997277287617632 -0.16211000186638735 LWTLVSEQTR ddPTM_PC-9_Lapatinib_30min_R1 1 LWTLVSEQTR 10 0 E9PLL6;P46776;E9PJD9 E9PLL6 RPL27A 60S ribosomal protein L27a 0 147.73 0.00068375 6012500.0 15142.0 11794.0 17380.0 14338.0 18416.0 14784.0 15878.0 15331.0 15958.0 16388.0 False True 14926.07230329728 11766.691717621197 15951.08348874012 15392.464350165861 17332.807087249057 14151.722783187248 16700.085148349335 16043.334228567126 14160.641994810225 19220.6439643626 0.7765646318079678 0.6121902959879008 0.8298932917292136 0.8008297941892766 0.9017807686041206 0.7362772448949294 0.8688618955386361 0.8346928572379474 0.7367412882245656 1.0 14.230369052218293 -14.522878745280336 0.08025721598087068 1.6063074775035187 0.6041074535894713 0.4064703321576183 0.07708940539066537 262.407929820822 1.4849045907049787 28.98762619502086 2.6703897349278285 3.0000000000000132e-15 14.522878745280336 -1.0022000239140474 LY(ph)GLILMS(ph)S(ph)FIFLS(ph)DT(ph)LSLKGK ddPTM_PC-9_AZD4547_30min_R2 1 LYGLILMSSFIFLSDTLSLKGK 22 1 Q8IZF6 Q8IZF6 GPR112 Probable G-protein coupled receptor 112 5 LY(1)GLILMS(1)S(1)FIFLS(0.902)DT(0.549)LS(0.549)LKGK 63.43600000000001 0.012083 0.0 575.87 0.0 402.29 1275.0 2592.4 0.0 631.1 1106.8 777.26 785.69 True False 758.9846811598919 0.0 396.95537174838375 981.0684485536344 2232.49000808127 0.0 687.2666773973017 935.7694917338015 818.3443767922607 758.1832322454239 1.0010570649420647 0.0 0.5235612644357311 1.2939727586010008 2.9445256939665647 0.0 0.9064651500692031 1.2342260444911723 1.0793490834249453 1.0 9.566402740422204 -5.737238021528293 7.312024123387714 1.2278643788817887 0.45245257279999196 0.16524620008192248 0.7173435587099054 0.3080399356372741 63.289019768566725 0.20187554012709358 0.34135137579047303 1.8313104704323915e-06 5.737238021528293 -0.7754118060817967 LY(ph)KSEPELTTVAEVDESNGEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LYKSEPELTTVAEVDESNGEEK 22 1 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 LY(0.578)KS(0.158)EPELT(0.207)T(0.057)VAEVDESNGEEK 61.345 0.029836 4553700.0 10913.0 14630.0 13380.0 17791.0 17632.0 15568.0 18677.0 14583.0 12718.0 13449.0 True False 12760.355358425086 16082.369713698343 13699.029943932564 16794.22794920023 14177.136172371062 14751.586674102311 16907.77935022973 14200.211701965703 12903.97668990786 15887.197237774586 0.8031848014126187 1.0122848903430053 0.8622685133763386 1.057091927408632 0.8923623191800278 0.9285203962236862 1.0642392800429603 0.8938147798783678 0.812224868665091 1.0 13.955577011610643 -4.743757905017032 24.794455763201224 0.9458349369909964 0.8031843142678337 0.22394238192439242 0.0802791215457657 1582.0886343116804 2218408.07376713 0.019404334320175482 0.584483776276073 1.8040231030106375e-05 4.743757905017032 -0.14265062272316276 LYAVHQEGNK ddPTM_PC-9_Lapatinib_30min_R1 1 LYAVHQEGNK 10 0 P50990-2;P50990;P50990-3;H7C2U0 P50990-2 CCT8 T-complex protein 1 subunit theta 0 82.029 0.012988 9519800.0 105830.0 123370.0 130250.0 108710.0 130230.0 125690.0 125190.0 118170.0 137640.0 107560.0 False True 104320.84479315483 123084.34434482997 119541.34777954 116704.89604592907 122570.12744203123 120314.5316977005 131671.7256406256 123660.60960079407 122137.5337865445 126151.6026853087 0.8269482319094134 0.9756859344218547 0.94760070609441 0.9251162376197083 0.9716097523373395 0.9537297120023988 1.0437578503785412 0.9802539719552471 0.9681805953050198 1.0 16.944799009498226 -4.073988999422967 1.6677657032333384 0.9746668842824703 3.7161844178395415e-15 0.6618342507065572 0.031088769282149438 6.19281280668317 2.9169478113908047 0.009052513748226064 17.307424837121122 8.433561195057868e-05 4.073988999422967 -0.9746668842824666 LYDNLLEQNLIR ddPTM_PC-9_Lapatinib_30min_R1 1 LYDNLLEQNLIR 12 0 O00231-2;O00231 O00231-2 PSMD11 26S proteasome non-ATPase regulatory subunit 11 0 145.23 0.00049443 3835200.0 12206.0 9791.0 8299.5 9719.9 14057.0 9443.7 10764.0 10283.0 11910.0 11003.0 False True 12031.940201693738 9768.329541057252 7617.147146996472 10434.733870635882 13230.194897125326 9039.81496533992 11321.3072513435 10760.78571993711 10568.570382139982 12904.853889424076 0.9323577240618186 0.7569500301791637 0.5902544276955323 0.8085898499933787 1.0252107470947716 0.7004972735683839 0.8772906185804753 0.8338556803619377 0.8189608710565294 1.0 13.655626186677061 -14.522878745107931 0.17451814972377258 1.7565259501279364 0.7705423334444914 0.19493574456976825 0.11339091612651644 226.16805247898716 2.147626399013535 59.067703305801345 0.39603621628557917 3.0000000011909404e-15 14.522878745107931 -0.985983616683445 LYEALT(ph)PVH ddPTM_PC-9_AZD4547_30min_R2 2 LYEALTPVH 9 0 G5E9W3;Q9UKF6 G5E9W3 CPSF3 Cleavage and polyadenylation specificity factor subunit 3 1 LYEALT(1)PVH;LYEALT(1)PVH 102.07 0.0080596 9645600.0 32643.0 29383.0 44019.0 62077.0 53613.0 44805.0 39687.0 57438.0 41434.0 44674.0 True False 43022.79498342046 38880.48013411784 43435.27929849634 47766.10673008941 46169.76037774309 42003.33626709219 43219.066116093636 48562.27689393396 43624.11665081248 43109.9768577073 0.9979776868223661 0.9018905359761681 1.0075458737048912 1.1080058541379076 1.0709762273854888 0.9743298263817728 1.002530487519082 1.1264742046655005 1.011926236815255 1.0 15.39573416759868 -5.515713100427904 24.663352206295986 1.0450996557950083 0.9511301187310186 0.3400120058181533 0.05081613190754543 276.2808337944746 950926.2478455985 0.013793637518999749 0.02520370018266819 3.0499091268102485e-06 5.515713100427904 -0.0939695370639897 LYEALT(ph)PVH ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LYEALTPVH 9 0 G5E9W3;Q9UKF6 G5E9W3 CPSF3 Cleavage and polyadenylation specificity factor subunit 3 1 LYEALT(1)PVH;LYEALT(1)PVH 122.33 0.0038214 9359600.0 51165.0 60963.0 73531.0 61853.0 75071.0 67831.0 69238.0 61591.0 60826.0 53745.0 True False 59826.223945186415 67015.00374956896 75284.25790787028 58387.57694013159 60361.37645168268 64273.822950349066 62679.2754002894 59974.301511058766 61715.465178513514 63488.54305481412 0.942315275584986 1.055544835730601 1.1857928105685476 0.9196553288318727 0.9507443949307273 1.0123688441685763 0.9872533276779398 0.9446476265690762 0.972072474953949 1.0 15.954208650658053 -5.802377840473016 24.999999934568898 0.9689683520479596 1.0606515232428746 0.32752930795290325 0.06019627893260734 169.72962770463567 103648.52959883741 0.01728654073285263 0.025640382579972528 1.5762393292572948e-06 5.802377840473016 0.09168317119491498 LYEALT(ph)PVH ddPTM_PC-9_Lapatinib_30min_R1 2 LYEALTPVH 9 0 G5E9W3;Q9UKF6 G5E9W3 CPSF3 Cleavage and polyadenylation specificity factor subunit 3 1 LYEALT(1)PVH;LYEALT(1)PVH 122.33 0.0038214 6504200.0 59575.0 52208.0 60346.0 48927.0 56869.0 49297.0 46571.0 42817.0 58028.0 39994.0 True False 58725.44957528303 52087.115583649975 55384.584822296405 52525.25479568736 53524.077228755785 47188.68222691976 48982.218506346944 44806.43413114338 51492.27557807043 46906.9096113448 1.2519573355367632 1.1104358827990728 1.180734038571179 1.119776494143279 1.1410702105987935 1.0060070598960713 1.0442431384245405 0.9552203396556015 1.097754595319079 1.0 15.517512833799367 -6.708133059630391 4.793659445362635 1.0190125456100467 1.1588768030777137 0.6665916214588261 0.04961885147539443 0.12156185628255427 5.822662699727197 0.015986284503531616 0.015617762221457542 1.9582446124066265e-07 6.708133059630391 0.13986425746766695 LYEEGSNKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LYEEGSNKR 9 1 P25788-2;P25788 P25788-2 PSMA3 Proteasome subunit alpha type-3 0 72.243 0.020761 3733200.0 14527.0 16180.0 15795.0 16254.0 18313.0 18240.0 16510.0 15052.0 14717.0 13467.0 False True 16986.13417867141 17786.2434701052 16171.612702871065 15343.34107617899 14724.699110970454 17283.462290315143 14946.053277951109 14656.90094891229 14932.208283171401 15908.460495286647 1.0677421730219625 1.118036750028383 1.0165416513849588 0.9644768002991182 0.9255891929538426 1.0864321092186062 0.9395034348156643 0.9213274253190515 0.9386331435147676 1.0 13.957506608475498 -5.481163901585863 3.3653846313900413 0.9671256074151472 1.0921351530799457 0.5245568658690885 0.04708625677377043 0.1897567470919544 4.323593885060769 0.013355872238179809 0.02908689637957976 3.302448839721619e-06 5.481163901585863 0.1250095456647985 LYEQLSGK ddPTM_PC-9_Lapatinib_30min_R1 1 LYEQLSGK 8 0 P30086 P30086 PEBP1 Phosphatidylethanolamine-binding protein 1;Hippocampal cholinergic neurostimulating peptide 0 99.13600000000001 0.024384 5568400.0 51566.0 37185.0 49411.0 47819.0 45622.0 42238.0 39282.0 34566.0 38409.0 38870.0 False True 50830.65938395376 37098.90041713959 45348.61831197573 51335.7687795077 42938.60365630305 40431.57920158704 41315.82975169785 36172.06254938695 34082.97395529929 45588.62770898063 1.1149855114840512 0.8137753269074905 0.9947353230604566 1.1260652351111442 0.941870940498708 0.8868786193716094 0.9062749160918245 0.7934448648091532 0.74762009009947 1.0 15.476386361964552 -6.824646763493314 2.07882869824984 0.8461118618736249 0.9988514912486202 0.30032207159569146 0.10233223724715883 0.4082185490621644 3.6226388214168592 0.0420864868902353 0.03708350379881571 1.4974531250618346e-07 6.824646763493314 0.1527396293749953 LYGPSSVSFADDFVR ddPTM_PC-9_Lapatinib_30min_R1 1 LYGPSSVSFADDFVR 15 0 P50454;E9PQ34;E9PJH8;E9PIG2;E9PRS3;E9PNX1;E9PK86;E9PMI5;E9PR70;E9PPV6 P50454 SERPINH1 Serpin H1 0 197.07 4.346600000000001e-09 3731400.0 9167.3 6649.7 8988.6 9651.9 9603.2 8557.9 7745.6 7355.4 9061.8 7207.1 False True 9036.572620923069 6634.303028206346 8249.592004999397 10361.732923794534 9038.358656617631 8191.898566439261 8146.6292684881255 7697.15873620786 8041.164659015617 8452.8376321429 1.0690578731289535 0.7848610510367117 0.9759553376051329 1.22582893162325 1.0692691673442558 0.9691300037857834 0.9637744888781038 0.9106005664817832 0.9512976599051366 1.0 13.045220022576355 -6.948810989518045 8.828804418479377 0.9514236933619774 1.0201427767807982 0.09053986854679286 0.1042126949522454 0.8820288054491018 140.77468249780452 0.04056337076943227 0.035731769602006934 1.1250945228757412e-07 6.948810989518045 0.06871908341882083 LYHS(ph)LGPVTR ddPTM_PC-9_AZD4547_30min_R2 3 LYHSLGPVTR 10 0 Q86X27 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 LYHS(1)LGPVTR;LYHS(1)LGPVTR;LYHS(1)LGPVTR 98.337 0.0027193 71674000.0 107721.0 90974.0 127526.0 158997.0 127176.0 114306.0 97849.0 142566.0 113000.0 121762.0 True False 141974.03726400874 120379.56640646748 125834.92191599171 122342.69812916238 109519.80761755278 107158.42775016715 106557.37144136979 120535.70054076711 118972.94930592766 117499.14944146853 1.208298425468452 1.0245143643906445 1.0709432580078002 1.0412219893566688 0.9320902162964966 0.9119932208832494 0.9068778110130123 1.02584317515261 1.0125430683665781 1.0 16.84229078781418 -1.5228787452849224 0.6374362628001631 0.9673024107688072 19.63267767818218 0.6532255350049304 0.04953942792216509 138.16111058080165 0.9348753507758345 0.023241799377174358 3628.337995784324 0.02999999999968329 1.5228787452849224 18.665375267413374 LYHS(ph)LGPVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LYHSLGPVTR 10 0 Q86X27 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 LY(0.001)HS(0.999)LGPVTR;LYHS(1)LGPVTR;LY(0.022)HS(0.978)LGPVTR 109.44 0.0010672000000000001 79387000.0 81743.0 82129.0 95649.0 87089.0 92420.0 85719.0 93436.0 83511.0 79228.0 65325.0 True False 95580.4754021571 90282.22434834793 97929.63491085234 82209.68567634762 74310.96444252125 81223.74474032466 84585.06566194071 81318.92473721837 80386.55961534976 77167.90538758466 1.2386039885635511 1.1699452498405276 1.269046171708167 1.065335196846928 0.9629776014948949 1.052558629554205 1.0961171647345165 1.0537920438397899 1.0417097524106562 1.0 16.235713325933546 -5.838707364942015 6.077644029993083 1.0393315774024379 1.219722881287135 0.8164673668675007 0.040688828530214494 0.08503629565460988 5.139785032337448 0.011754393281120056 0.017728131635270417 1.4497483897923218e-06 5.838707364942015 0.18039130388469715 LYHS(ph)LGPVTR ddPTM_PC-9_Lapatinib_30min_R1 4 LYHSLGPVTR 10 0 Q86X27 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 LY(0.004)HS(0.994)LGPVT(0.002)R;LYHS(0.999)LGPVTR;LYHS(0.997)LGPVT(0.003)R;LY(0.002)HS(0.998)LGPVTR 90.412 0.0049457 132551900.0 163867.0 131550.0 147331.0 118705.0 118961.0 121898.0 119755.0 120115.0 132664.0 94369.0 True False 161530.2265304725 131245.4040574077 135218.01389410638 127434.96168827174 111963.9478663246 116684.70669811679 125955.3279342847 125695.9814013662 117721.98330614754 110680.55591121154 1.45942731494819 1.1858036217553276 1.2216961938877402 1.1513762344173684 1.0115954599662709 1.054247566227638 1.1380077277107883 1.1356645290271228 1.0636193714150177 1.0 16.75604226968754 -1.5228787452803514 0.6547175690999995 1.078446097858886 34.700298107484464 0.8059122552805591 0.055758790179802314 100.25285447421693 0.6355806791739439 0.024085145117629058 4890.661206612949 0.029999999999999045 1.5228787452803514 33.62185200962558 LYINHT(ph)PPPLSK ddPTM_PC-9_Lapatinib_30min_R1 1 LYINHTPPPLSK 12 0 A0A0C4DG98;Q8NI27;Q8NI27-2;H0Y7U4;H0Y594;B7ZBA0 A0A0C4DG98 THOC2 THO complex subunit 2 1 LYINHT(0.891)PPPLS(0.109)K 78.985 0.038821 5758900.0 43463.0 39117.0 39552.0 30451.0 29589.0 32405.0 29761.0 28284.0 33172.0 21996.0 True False 42843.20964986199 39026.426989841304 36300.18723513518 32690.468121558155 27848.63319421224 31019.113689744492 31301.87895830863 29598.17789581846 29435.820043354102 25797.97929217233 1.6607195922070357 1.5127706921480775 1.4070942078067892 1.2671716552418955 1.0794889351144694 1.2023854015246989 1.2133461541232533 1.1473060568274505 1.1410126238951426 1.0 14.654970445999036 -5.400929719049825 1.0008820652943158 1.137518858379522 1.7037994848495803 0.8979646312639343 0.062153315113386336 0.2606783253469868 0.39167636294264263 0.02257392996622905 0.12849057714479137 3.972558313323143e-06 5.400929719049825 0.5662806264700584 LYKS(ph)EPELTTVAEVDESNGEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LYKSEPELTTVAEVDESNGEEK 22 1 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 LY(0.448)KS(0.508)EPELT(0.022)T(0.022)VAEVDESNGEEK 76.733 0.0031994 0.0 8177.9 10821.0 13837.0 15373.0 18133.0 16991.0 21165.0 14064.0 10851.0 12844.0 True False 9562.256949112478 11895.237366502379 14166.926557114717 14511.70064993846 14579.968818829648 16099.962049053973 19160.097978669608 13694.834902039756 11009.67534692484 15172.51552695195 0.6302354367096481 0.7839990241151559 0.9337229895694661 0.9564465842305688 0.9609460470104828 1.061126747272365 1.2628161720865767 0.9026080663890381 0.725632827817353 1.0 13.889172676564568 -4.8897352245924335 1.1781970680526552 0.9957349113895593 0.49789526788739513 0.4472858171994476 0.1260670918269927 1.28533943947961 1.7250492266491404 0.04239500353065907 0.7543639513999462 1.289035195566898e-05 4.8897352245924335 -0.49783964350216414 LYKS(ph)EPELTTVAEVDESNGEEKSEPVSEIETSVVK ddPTM_PC-9_AZD4547_30min_R2 2 LYKSEPELTTVAEVDESNGEEKSEPVSEIETSVVK 35 2 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 LY(0.456)KS(0.525)EPELT(0.014)T(0.005)VAEVDESNGEEKSEPVSEIETSVVK;LY(0.329)KS(0.371)EPELT(0.15)T(0.15)VAEVDESNGEEKSEPVSEIETSVVK 65.801 6.3312e-06 17213100.0 9918.8 13547.2 16787.9 22381.0 28311.0 19962.2 20216.7 24074.5 20415.6 24933.0 True False 13072.772076143458 17926.06747006505 16565.281476981014 17221.40623300306 24380.506333431902 18713.960478315978 22015.94713506261 20354.33920197453 21494.726936726536 24060.103259014562 0.543338153432301 0.7450536382610377 0.6884958596665426 0.7157660982419409 1.0133167788586814 0.7778005055445656 0.9150395947205227 0.845978879760144 0.893376337804084 1.0 14.554355213707186 -3.8332803679652017 0.334027930751521 0.9385271910965463 2.158886652977783e-14 0.672678222423678 0.08021489891566835 8.143589510197197 0.4465224118470377 0.07605913821567133 3.4880206112529155 0.00014679782873255624 3.8332803679652017 -0.9385271910965247 LYKSEPELT(ph)TVAEVDESNGEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LYKSEPELTTVAEVDESNGEEK 22 1 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 LY(0.009)KS(0.043)EPELT(0.693)T(0.255)VAEVDESNGEEK 62.325 0.0038061999999999996 5110000.0 14439.0 20858.0 21658.0 24581.0 28021.0 24656.0 34289.0 22848.0 22987.0 24763.0 True False 16883.23751675065 22928.64439428024 22174.408858422383 23203.806262677255 22530.486200431573 23362.995955592665 31040.89768913785 22248.26420945706 23323.141387868516 29252.335876199853 0.5771586101090515 0.7838226831292244 0.758038911910068 0.793229175300022 0.7702115241594337 0.7986711233751816 1.061142529625923 0.7605636795507529 0.7973086828544376 1.0 14.836264211850828 -2.7549357741391423 0.21388494681942816 0.9412756364112768 2.077112472591311e-31 0.4770089745695546 0.0918669652763328 30.947711823232996 0.613693818765558 0.1607112724834455 8.940025956089578 0.0017581836046124762 2.7549357741391423 -0.9412756364112768 LYNNHEIR ddPTM_PC-9_AZD4547_30min_R2 4 LYNNHEIR 8 0 O60506-2;O60506;O60506-4;O60506-3;B7Z645;O60506-5 O60506-2 SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0 ;;; 129.42 0.0031769000000000003 22099600.0 137006.0 134829.0 186712.0 259331.0 215943.0 178739.0 172580.0 202012.0 145785.0 179586.0 False True 180571.05809816808 178409.8375252007 184236.07688454652 199546.24457400964 185963.04189750552 167562.4220744066 187939.28566824022 170795.68717395084 153490.89747402366 173298.7488017243 1.041964003472202 1.0294929349393294 1.0631125623147801 1.151458080071402 1.073077810332438 0.9668992028679864 1.0844814920346977 0.9855563779595589 0.8857011290349054 1.0 17.402901712869898 -7.943393338530457 4.7685980055875135 0.9400058292325902 1.0578616551690692 0.4694524410204277 0.05070620313680515 0.17003043381175817 7.930764813100019 0.031019744105525326 0.013902997401266907 1.1392175360551416e-08 7.943393338530457 0.11785582593647892 LYNNHEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LYNNHEIR 8 0 O60506-2;O60506;O60506-4;O60506-3;B7Z645;O60506-5 O60506-2 SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0 ; 101.25 0.0038966 9902000.0 55508.0 49314.0 53680.0 66487.0 59848.0 51651.0 53582.0 53991.0 52498.0 33579.0 False True 64904.40806702644 54209.568015127865 54959.93478253369 62761.94894376235 48121.21402246276 48942.330633611105 48506.32505991381 52573.79345819312 53265.68393354162 39666.606888782255 1.6362480473564642 1.3666298246059048 1.3855466623760149 1.5822363914245328 1.2131416775169512 1.2338421274810887 1.222850373764423 1.3253917484195257 1.3428343917312775 1.0 15.27563737309789 -1.5228787453407782 0.06746875904890165 0.6635364139553681 2.8548096207704834 0.6088319234228234 0.10928108258473622 202.39135324189502 1.0153680425210996 5.98693744787092 42.43614134725371 0.02999999999582491 1.5228787453407782 2.191273206815115 LYNNHEIR ddPTM_PC-9_Lapatinib_30min_R1 4 LYNNHEIR 8 0 O60506-2;O60506;O60506-4;O60506-3;B7Z645;O60506-5 O60506-2 SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0 ;;; 104.17 0.0032417 22637800.0 152058.0 139910.0 151275.0 134968.0 148559.0 158400.0 136031.0 125273.0 147327.0 116296.0 False True 149889.6250359783 139586.04699104454 138837.75343838707 144893.9969600491 139821.05169823163 151625.6012484349 143074.01957520505 131093.64091157092 130733.48183791248 136397.60864532072 1.0989168103800215 1.0233760575232285 1.0178899382276674 1.0622913289984564 1.025098996140123 1.1116441318462702 1.0489481523627384 0.9611139243097591 0.9584734155997056 1.0 17.057458825354765 -7.746911546137284 10.190843813542 0.9698186031929947 1.054070677002394 0.595354216627658 0.03102464110328899 0.17493788343728067 116.5287343394425 0.015155165498457244 0.00843066900443131 1.7909705884298762e-08 7.746911546137284 0.08425207380939925 LYNSEESRPYT(ph)NK ddPTM_PC-9_AZD4547_30min_R2 1 LYNSEESRPYTNK 13 1 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 LYNSEES(0.003)RPY(0.052)T(0.944)NK 73.593 0.015082 36954000.0 80543.0 64172.0 109630.0 119220.0 83118.0 70948.0 94054.0 77575.0 73909.0 75774.0 True False 106153.9986015269 84914.34404814373 108176.23456903055 91735.67093063859 71578.50042111508 66511.61034432876 102424.62379325912 65587.56624615985 77815.67885178595 73121.17532381073 1.4517545448556206 1.1612825378162752 1.4794105003096785 1.2545705197488304 0.9789024876054843 0.9096080588117997 1.400751879871742 0.8969708973592266 1.0642016968024108 1.0 16.158001639499666 -6.0984390192336315 4.65611866636978 1.0493421713308073 1.3474308998611846 0.4759206255724783 0.15416615482470963 0.20869544378856686 7.443387843017728 0.045258633814484014 0.05993470730351525 7.971884186711873e-07 6.0984390192336315 0.29808872853037727 LYNSEESRPYT(ph)NK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LYNSEESRPYTNK 13 1 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 LYNSEES(0.007)RPY(0.428)T(0.565)NK 70.563 0.020123 30187000.0 53195.0 55457.0 43002.0 63720.0 57334.0 47963.0 46330.0 50572.0 44426.0 36897.0 True False 62199.8628508588 60962.404457455144 44027.330765993174 60149.97498302731 46099.81427556275 45447.735845964104 41941.286999847056 49244.53858546317 45075.64620426534 43586.13402350868 1.4270562013440007 1.3986650989641423 1.01012241054108 1.380025467516452 1.0576715579018383 1.0427108727158814 0.9622621491785791 1.1298212077928858 1.034173991663341 1.0 15.411581625625933 -1.6508066825168852 0.34977417163373314 1.0116806161632945 5.88413685036764 0.5991963547821643 0.11008227760602916 38.06375626235169 0.5844011707296415 0.09161663382928506 120.61943255549227 0.022345666740467937 1.6508066825168852 4.872456234204345 LYPPGDEEEAELADS(ph)SGLYHEGSPSPGSPWK ddPTM_PC-9_AZD4547_30min_R2 1 LYPPGDEEEAELADSSGLYHEGSPSPGSPWK 31 0 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 LYPPGDEEEAELADS(0.352)S(0.308)GLY(0.209)HEGS(0.109)PS(0.021)PGS(0.001)PWK 80.132 3.9097e-07 13893000.0 10448.0 9297.8 14260.0 28233.0 22675.0 19860.0 15119.0 25698.0 15733.0 16924.0 True False 13770.246668099664 12303.13202161117 14070.903082681521 21724.318045501786 19526.967648990452 18618.15106047208 16464.561710616068 21726.964581293134 16564.61426044392 16331.495911264685 0.8431711793529952 0.7533377278149431 0.8615807859325418 1.3302099307704809 1.1956631379689893 1.1400150458740383 1.0081478022634534 1.3303719818040007 1.0142741577652075 1.0 13.995369322618116 -5.635088100045203 6.544045310042767 1.1546248179571477 0.8011374250486095 0.627957770942027 0.11544213325927354 0.1228613361681398 6.556918058368721 0.030281737526563435 0.05282097413149039 2.3169245959490714e-06 5.635088100045203 -0.35348739290853814 LYPPGDEEEAELADSSGLY(ph)HEGSPSPGSPWK ddPTM_PC-9_AZD4547_30min_R2 1 LYPPGDEEEAELADSSGLYHEGSPSPGSPWK 31 0 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 LYPPGDEEEAELADS(0.069)S(0.083)GLY(0.311)HEGS(0.083)PS(0.18)PGS(0.273)PWK 88.244 8.887500000000001e-09 15819000.0 28146.0 24798.0 57783.0 87129.0 79996.0 69800.0 46974.0 70884.0 47944.0 72148.0 True False 37095.84252683125 32813.46854867965 57016.759665258534 67042.75517963115 68889.93623147247 65435.39496580815 51154.594999304114 59930.506552275794 50478.22196038407 69622.12048014202 0.5328169017404736 0.47130808890026377 0.8189460371509533 0.9629519284571837 0.9894834537698635 0.9398650100648969 0.7347462939439583 0.8607969153908416 0.7250313781347945 1.0 16.087258134426868 -5.324308261923286 4.4512214360062226 0.8818311913365685 0.5000321055069809 0.729074158062634 0.09241705272074946 0.10625912492665283 4.233542750020029 0.025885510166575035 0.05881131372381408 4.739054880635344e-06 5.324308261923286 -0.38179908582958766 LYPPGDEEEAELADSSGLYHEGS(ph)PSPGSPWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LYPPGDEEEAELADSSGLYHEGSPSPGSPWK 31 0 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 LYPPGDEEEAELADS(0.007)S(0.019)GLY(0.054)HEGS(0.826)PS(0.063)PGS(0.031)PWK 64.035 8.201200000000001e-05 2512600.0 4050.0 3699.8 5679.6 6343.7 7960.6 6877.6 5562.9 4806.1 6581.5 5599.6 True False 4735.585008853807 4067.0916928736237 5815.023204002948 5988.283055552889 6400.777575645252 6516.926548677159 5035.941840091716 4679.944967483877 6677.741986525285 6614.763153590791 0.7159114996102496 0.6148506905596194 0.8790977195980617 0.9052906228852925 0.9676503038768095 0.9852093563077127 0.76131854204908 0.7075000054905053 1.009520950557437 1.0 12.69147378534483 -5.272784011970829 21.9951950865984 0.8919190375515077 0.6653811207500713 0.47913426614254995 0.09821747048668528 116.60657720312582 226081.8305747609 0.02685263628517206 0.05696745485739618 5.336002053344326e-06 5.272784011970829 -0.22653791680143642 LYPPGDEEEAELADSSGLYHEGS(ph)PSPGSPWK ddPTM_PC-9_Lapatinib_30min_R1 1 LYPPGDEEEAELADSSGLYHEGSPSPGSPWK 31 0 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 LYPPGDEEEAELADS(0.086)S(0.026)GLY(0.105)HEGS(0.35)PS(0.25)PGS(0.182)PWK 82.62700000000001 1.3764e-07 7643300.0 55807.0 36173.0 77569.0 51457.0 64273.0 67981.0 52786.0 51290.0 73378.0 48029.0 True False 55011.181946249606 36089.24364096251 71191.57624499888 55241.31943551996 60492.58850557989 65073.61110145097 55519.00079611839 53673.12064335062 65113.39693540448 56330.74865538029 0.9765746640932554 0.6406668560673485 1.2638137774545484 0.9806601324167511 1.073882203761588 1.1552058627794508 0.9855896135123642 0.9528210067242586 1.1559121525927978 1.0 15.781635025176744 -5.257411127609637 24.999754733118056 1.066136180207749 0.808620774760013 0.43543333241945203 0.11939634707062594 296.8113872197174 1842024.7572940572 0.02887860630059073 0.07077521207276982 5.528265247122138e-06 5.257411127609637 -0.2575154054477359 LYPPGDEEEAELADSSGLYHEGSPS(ph)PGSPWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LYPPGDEEEAELADSSGLYHEGSPSPGSPWK 31 0 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 LYPPGDEEEAELADSSGLY(0.111)HEGS(0.132)PS(0.525)PGS(0.231)PWK 85.395 4.3651e-09 7773700.0 15470.0 18455.0 35629.0 42114.0 46098.0 48303.0 45329.0 42002.0 44474.0 34723.0 True False 18088.765453572432 20287.090435153998 36478.530483734954 39754.489115430166 37065.42781726184 45769.90564742828 41035.10896645949 40899.49200479762 45124.34811345824 41018.00503288322 0.4409957392874439 0.49458988604858495 0.8893297090994778 0.9691960660583048 0.9036379947671106 1.115849140169922 1.0004169859934084 0.9971107071640711 1.1001107459342074 1.0 15.323969705615 -5.303778955419257 1.9793612651363897 1.0151648628280727 0.41170190519608596 0.9323287359420845 0.05789546502820777 0.08513593427860457 0.6075970086999668 0.016714569833559526 0.0619815366935764 4.968451383421043e-06 5.303778955419257 -0.6034629576319868 down LYPPGDEEEAELADSSGLYHEGSPSPGS(ph)PWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LYPPGDEEEAELADSSGLYHEGSPSPGSPWK 31 0 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 LYPPGDEEEAELADS(0.003)S(0.003)GLY(0.01)HEGS(0.063)PS(0.124)PGS(0.797)PWK 112.91 2.2253e-16 7116400.0 23010.0 24060.0 45824.0 54980.0 60574.0 59755.0 50002.0 53720.0 48778.0 36035.0 True False 26905.138531784203 26448.517792999475 46916.61794848775 51899.64884756499 48704.959534097376 56621.34260733448 45265.44857686928 52309.9069210449 49491.28597109021 42567.86024709695 0.6320528768795487 0.6213259872465217 1.1021605896126145 1.219221463007515 1.144172134830737 1.3301430299446624 1.0633714805985885 1.2288592054521308 1.162644438405039 1.0 15.37747695173419 -5.295885682190592 4.140461290991266 1.1741555301252422 0.6171976557637577 0.8585061474738355 0.08614751605778269 0.060714336371358466 2.373799538767543 0.021289642204302323 0.051419414754737054 5.059578259756888e-06 5.295885682190592 -0.5569578743614845 LYPPGDEEEAELADSSGLYHEGSPSPGS(ph)PWK ddPTM_PC-9_Lapatinib_30min_R1 1 LYPPGDEEEAELADSSGLYHEGSPSPGSPWK 31 0 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 LYPPGDEEEAELADS(0.062)S(0.011)GLY(0.038)HEGS(0.271)PS(0.188)PGS(0.43)PWK 88.573 4.811500000000001e-09 7836400.0 36033.0 23265.0 44240.0 33979.0 45162.0 45214.0 28005.0 36954.0 49537.0 29981.0 True False 35519.162812357084 23211.131321897345 40602.7579713385 36477.929010621156 42505.65995190822 43280.30261898188 29454.9618704826 38671.01774720957 43957.62141226431 35163.17590282861 1.0101238554365004 0.6600976938499513 1.1546954144171122 1.037390055762477 1.2088117429827767 1.230841683316219 0.8376650036356121 1.09975895960236 1.2501038453903774 1.0 15.101777758686639 -5.278748033869118 24.923309455214767 1.102580993028232 0.8351107565326754 0.3655186045562031 0.14086697127047382 707.8695737641124 1019284.504294715 0.036331763078874334 0.07591984003723634 5.263225361926964e-06 5.278748033869118 -0.26747023649555657 LYPTTQPPEQGLDPTRS(ph)SLPR ddPTM_PC-9_AZD4547_30min_R2 1 LYPTTQPPEQGLDPTRSSLPR 21 1 P85299;P85299-5;P85299-2;P85299-4;P85299-3 P85299 PRR5 Proline-rich protein 5 1 LYPTTQPPEQGLDPT(0.056)RS(0.472)S(0.472)LPR 95.834 0.00015882 7371700.0 11146.0 11281.0 13575.0 11368.0 14786.0 12499.0 10245.0 11492.0 11918.0 11031.0 True False 14690.196148797742 14927.362638021415 13394.986630252577 8747.283233849188 12733.21912493816 11717.435554120862 11156.785152805189 9716.17545988874 12547.961148920776 10644.80804757508 1.3800339172996374 1.4023139328869265 1.2583586825038142 0.8217417537972276 1.1961905811762221 1.1007653216245765 1.048096414979201 0.91276192266352 1.1787869816759393 1.0 13.377862314186217 -5.551179579001105 9.10335302956399 1.0425170527925158 1.3762962424757577 0.6518581976725976 0.10662961347598024 0.15295949713201307 45.78103687615288 0.028157952163173433 0.049225832290082934 2.8107383612020133e-06 5.551179579001105 0.33377918968324183 LYPTTQPPEQGLDPTRS(ph)SLPR ddPTM_PC-9_Lapatinib_30min_R1 2 LYPTTQPPEQGLDPTRSSLPR 21 1 P85299;P85299-5;P85299-2;P85299-4;P85299-3 P85299 PRR5 Proline-rich protein 5 1 LYPTTQPPEQGLDPT(0.051)RS(0.474)S(0.474)LPR;LYPTTQPPEQGLDPT(0.12)RS(0.44)S(0.44)LPR 64.013 0.0022849 13192000.0 17856.800000000003 18881.3 24991.0 16612.9 25186.0 27545.0 26890.0 28561.0 26911.0 22122.4 True False 17602.158757463934 18837.581509913623 22936.336448049748 17834.668085009816 23704.60899758117 26366.96456053115 28282.23262621949 29888.048327056673 23879.999794606978 25946.227363754904 0.6784091772067388 0.7260239126798229 0.8839950458497189 0.6873703770099395 0.9136052292016403 1.016215736911486 1.0900325596363125 1.151922701826325 0.9203650095183278 1.0 14.663237162476445 -6.550411265827323 2.5111071739707023 1.051387590528149 0.7519978707160082 0.7522744201125673 0.07839048007661145 0.1396437018524037 1.7808289520321823 0.027794549865440075 0.02925600232197849 2.8157152576279353e-07 6.550411265827323 -0.2993897198121407 LYQAGEGR ddPTM_PC-9_Lapatinib_30min_R1 1 LYQAGEGR 8 0 P20073-2;P20073 P20073-2 ANXA7 Annexin A7 0 95.815 0.029077 3703900.0 17490.0 18720.0 19250.0 12967.0 19623.0 18035.0 12695.0 12222.0 14931.0 12992.0 False True 17240.589392726815 18676.654990153365 17667.33930714888 13920.63643664394 18468.813720302365 17263.685091638385 13352.284982887933 12789.878738604626 13249.313549599668 15237.649889248176 1.131446746580779 1.225691305805089 1.159453028226821 0.9135684661232745 1.2120513238287571 1.1329624461197128 0.8762693118647795 0.8393603233809225 0.8695116140546387 1.0 13.89535279192317 -7.261066543354654 24.50025613073469 0.8828986597949356 1.1289220112063956 0.6197566338744285 0.0891281351173851 16.889226787370827 1109907.8791604072 0.036428827282216386 0.026456283623672614 5.481929634078183e-08 7.261066543354654 0.24602335141145992 LYQVEYAFK ddPTM_PC-9_Lapatinib_30min_R1 1 LYQVEYAFK 9 0 G3V3U4;G3V3I1;G3V295;G3V5Z7;P60900 G3V3U4 PSMA6 Proteasome subunit alpha type;Proteasome subunit alpha type-6 0 129.38 0.0059886 4320900.0 43818.0 34654.0 46064.0 36074.0 41990.0 41572.0 41723.0 32805.0 45177.0 41185.0 False True 43193.147284762934 34573.7607921354 42276.79573218214 38727.002299336295 39520.23075551627 39794.062469065226 43883.2127877931 34329.2400605404 40088.69052509972 48303.77237443703 0.8941982201709218 0.7157569500810308 0.8752276199975544 0.8017386716535438 0.8181603384755696 0.8238292893688102 0.9084841748512514 0.710694804422933 0.8299287727331865 1.0 15.559848243007401 -8.572455440505845 22.23044210587306 1.0000000006305625 0.8165028440400749 0.4255936467117396 0.06290088834431039 9683.694904150942 4342208.652765073 0.056903846957504216 0.014692510036967896 2.6763601790918947e-09 8.572455440505845 -0.1834971565904876 LYRDS(ph)S(ph)VQS(ph)ILS(ph)FK ddPTM_PC-9_AZD4547_30min_R2 1 LYRDSSVQSILSFK 14 1 A0A1B0GU80;Q96N23 A0A1B0GU80 CFAP54 Cilia- and flagella-associated protein 54 4 LY(0.285)RDS(0.841)S(0.874)VQS(0.999)ILS(1)FK 63.31 0.032452999999999996 6544900.0 8552.2 6491.4 10280.0 11772.0 11119.0 10397.0 9081.7 10263.0 8126.2 9229.0 True False 11271.621703189303 8589.618103754292 10143.680483167325 9058.147275586969 9575.318777910687 9746.873946411282 9889.9537064159 8677.089170278286 8555.7343420339 8905.895519088972 1.2656359687837808 0.9644867363807752 1.1389848961763895 1.017095614491733 1.0751663049927844 1.094429406399362 1.1104951416977313 0.9743084400305101 0.960682092406706 1.0 13.120544971338886 -4.748322170575955 24.999649559101318 1.0442945566414543 1.2656365001194771 0.5516810533753266 0.061461811706134406 520.5580666667745 992055.9185391349 0.015414707594366394 0.2847987879214249 1.7851628048456187e-05 4.748322170575955 0.22134194347802283 LYREEGLAYIWMPT(ph)PDMS(ph)T(ph)EDEK ddPTM_PC-9_Lapatinib_30min_R1 2 LYREEGLAYIWMPTPDMSTEDEK 23 1 H0Y7S8;A0A1W2PPT8 H0Y7S8 EPM2A 3 LY(0.018)REEGLAY(0.272)IWMPT(0.816)PDMS(0.947)T(0.947)EDEK;LY(0.017)REEGLAY(0.155)IWMPT(0.885)PDMS(0.971)T(0.971)EDEK 50.425 0.013702 3917700.0 17373.6 20944.9 20405.9 20381.1 24652.5 22135.5 19901.9 24375.7 23452.9 22845.4 True False 17125.84927807196 20896.40337090082 18728.205671051903 21879.99408335652 23202.48841867981 21188.816265370755 20932.32300125541 25508.28400986785 20811.38743201433 26794.19695041797 0.6391626257641885 0.7798854136053834 0.6989649925208808 0.8165945082752408 0.8659519992935586 0.7907987055771876 0.7812259885970899 0.9520077820234855 0.7767124900412321 1.0 14.70963295719556 -2.0307573373878895 0.08219745169778149 1.139283581482758 3.931356635403299e-15 0.6142508852805593 0.06338920214668806 112.6975719084524 0.7468574155708184 1.6623158264685205 14.636530955950906 0.009316282785904711 2.0307573373878895 -1.139283581482754 LYRPGSVAYVSR ddPTM_PC-9_Lapatinib_30min_R1 2 LYRPGSVAYVSR 12 1 P53396;P53396-2;P53396-3 P53396 ACLY ATP-citrate synthase 0 ; 100.38 0.003956800000000001 12062100.0 28962.0 25973.0 25982.3 21616.7 22424.0 27410.0 21249.1 20493.3 26975.0 19675.0 False True 28548.996569019666 25912.861114276377 23846.135588578392 23206.464229197263 21105.064407280253 26237.738195830796 22349.274425355194 21445.49353246981 23936.791440657085 23075.79753471041 1.2371835264231503 1.122945418259043 1.033382943870488 1.0056624996076649 0.9145973990946229 1.1370241117935023 0.9685157963332627 0.929350047391068 1.0373115557393662 1.0 14.494092890020204 -4.913768942345752 1.438896264720538 0.9966716963264783 1.298848244988358 0.6309391219473109 0.057972730167960035 0.5957797007699611 1.3663427574347011 0.016941426950568543 0.24318080737927844 1.219638310403485e-05 4.913768942345752 0.3021765486618797 LYS(ph)GDHQR ddPTM_PC-9_AZD4547_30min_R2 3 LYSGDHQR 8 0 H0YDE2;A0A1B0GTN9;E9PKC0;Q6IQ23-3;Q6IQ23;Q6IQ23-2;A0A1B0GUM1;A0A1B0GUN0 H0YDE2 PLEKHA7 Pleckstrin homology domain-containing family A member 7 1 LYS(1)GDHQR;LYS(1)GDHQR;LYS(1)GDHQR 92.538 0.004850899999999999 4574000.0 68460.0 80120.9 86928.0 131923.0 122402.0 98059.0 88773.0 124797.0 82990.0 106052.0 True False 90228.8559435398 106018.41407540556 85775.27792225381 101510.19054003216 105408.59511231432 91927.35522854152 96673.62502391146 105512.49119976822 87376.6819725571 102339.15175971652 0.8816650753114444 1.0359516592860534 0.8381472432334278 0.9918998623163235 1.0299928551274744 0.8982618445419501 0.944639694209043 1.0310080686177898 0.8537952530397163 1.0 16.64299865513776 -4.454749241834609 15.718535577419997 0.9565495179973224 3.9880778959582226e-05 0.09761372770252041 0.06963987767414409 849485.5558150285 4286827.686984685 0.016334824435047954 26513305.893332895 3.50954453761689e-05 4.454749241834609 -0.9565096372183628 LYS(ph)GDHQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LYSGDHQR 8 0 H0YDE2;A0A1B0GTN9;E9PKC0;Q6IQ23-3;Q6IQ23;Q6IQ23-2;A0A1B0GUM1;A0A1B0GUN0 H0YDE2 PLEKHA7 Pleckstrin homology domain-containing family A member 7 1 LYS(1)GDHQR;LY(0.001)S(0.999)GDHQR 73.499 0.023385 0.0 42515.0 38482.0 48442.0 49423.0 55993.0 37841.0 42360.0 38183.0 36982.0 30682.0 True False 49711.949790473955 42302.238641321936 49597.040997308046 46653.98954152787 45021.573599113704 35856.55134472672 38347.35414015803 37180.73670823263 37522.79178692971 36244.403721421615 1.3715758761701626 1.1671384903021578 1.368405488982968 1.2872053269275845 1.2421662098555784 0.9892989720654265 1.0580213826912401 1.025833863732668 1.0352713228594936 1.0 15.145470634080395 -6.679667466860297 4.6194630577176365 1.0255108410969433 1.2905346385710188 0.8487028513312977 0.056309743973635557 0.07722000403692308 2.9894098759162997 0.01828058561743005 0.018025739296398627 2.090896487945945e-07 6.679667466860297 0.26502379747407545 LYS(ph)GDHQR ddPTM_PC-9_Lapatinib_30min_R1 2 LYSGDHQR 8 0 H0YDE2;A0A1B0GTN9;E9PKC0;Q6IQ23-3;Q6IQ23;Q6IQ23-2;A0A1B0GUM1;A0A1B0GUN0 H0YDE2 PLEKHA7 Pleckstrin homology domain-containing family A member 7 1 LYS(1)GDHQR;LYS(1)GDHQR 105.98 0.002759 4915600.0 62439.0 65282.2 60833.0 60042.0 54441.0 44818.0 42480.0 51193.0 56652.0 52173.0 True False 61548.608410089764 65131.043076826405 55831.545562170744 64457.688974240424 51238.887415124154 42901.238615860806 44679.40654376367 53571.61366923473 50271.255187992785 61191.03353384737 1.005843582884486 1.0643886745400313 0.9124138348029036 1.053384544299062 0.8373594047366718 0.7011033502503321 0.7301626392541578 0.8754814320892617 0.8215461038125074 1.0 15.901032646454818 -6.3382882887143905 5.6122254481343585 0.8082192639802598 1.0057418558107036 0.5107562672392811 0.08594869038753078 0.17184551056777714 9.487827478200057 0.026615048806442478 0.03035728252467889 4.5889329407589774e-07 6.3382882887143905 0.19752259183044385 LYS(ph)SGSSTPTGLAGGSR ddPTM_PC-9_AZD4547_30min_R2 1 LYSSGSSTPTGLAGGSR 17 0 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 LYS(0.837)S(0.16)GS(0.002)STPTGLAGGSR 142.74 0.00011163 6962100.0 10776.0 12987.0 11720.0 14460.0 13593.0 13745.0 13414.0 13210.0 14015.0 10738.0 True False 14202.543845275824 17184.793775373117 11564.585142288037 11126.470404772987 11705.84658225919 12885.522977149476 14607.820013638728 11168.698035601306 14755.804287810426 10362.065888392823 1.3706285984134645 1.6584331696464933 1.11605014548713 1.0737695093443114 1.1296827011466524 1.2435283770568695 1.409740120452412 1.0778447228474046 1.4240214689562336 1.0 13.339024041822302 -5.26892770215949 24.994893936631062 1.1913741581352788 1.5145308897914307 0.44308871184724474 0.1479079780325084 457.9136806643981 1528450.7920705078 0.037693052306748666 0.08102418323413976 5.3835939678466715e-06 5.26892770215949 0.3231567316561519 LYS(ph)SGSSTPTGLAGGSR ddPTM_PC-9_Lapatinib_30min_R1 2 LYSSGSSTPTGLAGGSR 17 0 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 LYS(0.891)S(0.094)GS(0.003)S(0.003)T(0.003)PT(0.007)GLAGGSR;LY(0.001)S(0.889)S(0.073)GS(0.01)S(0.013)T(0.013)PT(0.001)GLAGGSR 73.252 0.010915000000000001 9002400.0 17498.7 26603.0 16402.2 19081.6 27607.0 28231.0 40337.0 41167.0 34880.0 36045.0 True False 17249.165329131443 26541.402387983457 15053.674430322968 20484.924518351578 25983.210537450304 27023.625939675254 42425.45248954319 43079.7691075222 30951.447097316744 42275.33022305652 0.40801964734799234 0.6278224734837922 0.3560865012974601 0.48455977541198053 0.6146187481057058 0.6392292099692897 1.0035510607650984 1.0190285653647468 0.7321396884189483 1.0 15.367528403476378 -6.986730309348266 1.9531822806581505 0.9414091468325543 0.48537208228313755 0.7822604042875456 0.10941059227563457 0.15194964489493726 1.1681439307311101 0.048042979566871626 0.03750415933926993 1.0310261741730449e-07 6.986730309348266 -0.4560370645494167 LYS(ph)VSYLLK ddPTM_PC-9_AZD4547_30min_R2 2 LYSVSYLLK 9 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 LYS(0.999)VS(0.001)YLLK;LYS(0.989)VS(0.011)YLLK 163.9 0.00032942 16232800.0 31219.0 30141.0 43746.0 51999.0 47616.0 40100.0 29246.0 44644.0 30576.0 33169.0 True False 41145.99260446051 39883.48881061996 43165.89945687136 40011.433926541504 41005.34031198804 37592.540660872604 31848.83734299075 37745.295617061674 32192.184937858827 32007.763405857855 1.2855003982230835 1.2460567239546871 1.348607177250361 1.2500540390528776 1.2811060801731464 1.17448195877356 0.9950347651333233 1.1792543933311432 1.005761775031342 1.0 14.966134249309826 -6.975831035959985 3.1589802467160424 1.060052418155849 1.282260110376489 0.7917567744853972 0.056985066795616886 0.11314527236927527 2.3331551788125724 0.02121141060166522 0.017508937929893293 1.0572287483691614e-07 6.975831035959985 0.22220769222063996 LYS(ph)VSYLLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LYSVSYLLK 9 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 LY(0.004)S(0.841)VS(0.154)Y(0.002)LLK 100.82 0.0059051 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LYSESLAR ddPTM_PC-9_AZD4547_30min_R2 2 LYSESLAR 8 0 P50395;P50395-2;Q5SX87;Q5SX91;P31150 P50395 GDI2;GDI1 Rab GDP dissociation inhibitor beta;Rab GDP dissociation inhibitor alpha 0 ; 123.69 0.015127000000000002 5927100.0 24414.7 22242.2 32686.0 37632.0 33979.0 32605.0 28106.6 39113.0 28508.0 32915.0 False True 32178.066742692627 29431.556180072683 32252.562283346997 28956.523808604194 29261.60237023358 30566.204195704522 30608.032950301036 33068.984577325806 30014.87467976451 31762.655868546255 1.0130785938010223 0.9266087918428131 1.0154239751495682 0.9116531038350322 0.9212580488022286 0.9623314977880503 0.9636484139417129 1.0411278173395184 0.9449737076138987 1.0 14.955043929567614 -7.54894101970208 24.929829003903116 0.9963081062981812 0.9563327317592806 0.15060994365025926 0.03938975159058086 377.0099977558559 360623.3961508494 0.01785764904518854 0.010310491581104506 2.8252636398793032e-08 7.54894101970208 -0.039975374538900654 LYSESLAR ddPTM_PC-9_Lapatinib_30min_R1 2 LYSESLAR 8 0 P50395;P50395-2;Q5SX87;Q5SX91;P31150 P50395 GDI2;GDI1 Rab GDP dissociation inhibitor beta;Rab GDP dissociation inhibitor alpha 0 ; 148.04 0.0044831 18238000.0 75448.0 84235.0 89273.0 72696.0 74373.0 92503.0 69309.0 66051.0 87261.0 73953.0 False True 74372.09768453121 84039.959032883 81933.31854374557 78042.30634674706 69998.52636294393 88546.86232502495 72897.4808884584 69119.97059103035 77432.74728093337 86735.67751382156 0.8574568138085947 0.9689203040985183 0.9446322539036981 0.8997716808554451 0.8070326810070686 1.0208816586567249 0.8404555423786481 0.7969035646261701 0.8927439030910234 1.0 16.40433792760684 -5.985535973157404 15.884322083910236 0.8835959756090436 0.927198874790834 0.02365171006478395 0.07391082806627144 10.19986022683765 11188.320091988195 0.0206520610815374 0.030515683811636746 1.0338654610609285e-06 5.985535973157404 0.04360289918179039 LYSGS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 LYSGSPTR 8 0 Q6PJI9-3;Q6PJI9;H3BMH3;Q6PJI9-4 Q6PJI9-3 WDR59 WD repeat-containing protein 59 1 LYS(0.003)GS(0.499)PT(0.499)R;LYS(0.052)GS(0.829)PT(0.118)R;LYS(0.213)GS(0.726)PT(0.061)R 85.86200000000001 0.012908000000000001 47204000.0 101412.0 103348.0 105515.0 120968.0 139655.0 119809.0 147119.0 117331.0 111253.0 96558.0 True False 118579.04862169942 113607.70643686214 108030.87776786591 114190.55514354775 112290.60527180582 113526.0051283094 133182.82327067782 114251.18557247074 112879.86465500212 114063.2010472928 1.0395907491017569 0.9960066471373024 0.94711420314317 1.0011165222007241 0.9844595298114418 0.9952903660948402 1.1676230550066509 1.0016480733790734 0.9896256077207579 1.0 16.79947390033574 -7.044716933229842 24.99979828568223 1.045803682141632 0.9914423312456896 0.15510377778535456 0.051468501325866924 751.7494109530528 420276.6766323234 0.019874089502993575 0.015395237580351597 9.02158959989343e-08 7.044716933229842 -0.05436135089594252 LYSGS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 1 LYSGSPTR 8 0 Q6PJI9-3;Q6PJI9;H3BMH3;Q6PJI9-4 Q6PJI9-3 WDR59 WD repeat-containing protein 59 1 LYS(0.023)GS(0.972)PT(0.005)R 102.06 0.0043946 22170000.0 42626.0 42465.0 42565.0 37719.0 41671.0 41518.0 43138.0 40137.0 43119.0 37305.0 True False 42018.14542334898 42366.67490154181 39065.47000565153 40492.98108689542 39219.99370833817 39742.37192318504 45371.47456414491 42001.91154732235 38262.48415680048 43753.11954421204 0.960346276129868 0.968312096209066 0.8928613642320135 0.9254878625506399 0.8963930827539464 0.9083323049234425 1.036988334472872 0.9599752425625306 0.8745087105877483 1.0 15.417098262563417 LYSGSPT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 LYSGSPTR 8 0 Q6PJI9-3;Q6PJI9;H3BMH3;Q6PJI9-4 Q6PJI9-3 WDR59 WD repeat-containing protein 59 1 LYS(0.002)GS(0.228)PT(0.77)R 82.831 0.03891 26887000.0 35910.0 39481.0 53635.0 68766.0 58001.0 54418.0 55006.0 45265.0 41426.0 46161.0 True False 47328.63302559904 52242.46115696513 52923.76485551354 52913.061124109234 49948.562320136465 51015.23385744053 59901.42743925835 38270.33433622205 43615.69378714482 44544.917440314915 1.0624923278624094 1.1728040853810997 1.1880988426216148 1.1878585518764666 1.1213077762925885 1.1452537525924276 1.3447421362834355 0.859140313538574 0.9791396256505548 1.0 15.442973209681396 -7.775959481603415 24.999986704613637 0.9393549450991131 1.1724229183191757 0.6565018096589823 0.07570262196463301 142.78714396741424 245840.1120536024 0.04007025930084336 0.019382912104440132 1.675099150555549e-08 7.775959481603415 0.23306797322006256 LYSGSPT(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 LYSGSPTR 8 0 Q6PJI9-3;Q6PJI9;H3BMH3;Q6PJI9-4 Q6PJI9-3 WDR59 WD repeat-containing protein 59 1 LYS(0.003)GS(0.226)PT(0.771)R 84.81700000000001 0.033477 25014000.0 75070.0 70561.0 77957.0 65022.0 66660.0 69429.0 65419.0 64421.0 73235.0 55652.0 True False 73999.4880338479 70397.6203397548 71547.67638272232 69803.93478703336 62739.189858602476 66459.68351690388 68806.07572237472 67414.2348404229 64986.50310126124 65271.37404837127 1.1337203960040492 1.0785374349187833 1.0961570432039598 1.0694417852350266 0.9612052875140603 1.0182056757017552 1.0541539338728179 1.0328300242379393 0.9956355913865255 1.0 15.994162789801383 -6.040073251589189 6.021837010228697 1.0143426649787959 1.0979685245005135 0.716056016612991 0.026447193496199506 0.1180743599736368 11.794552530544381 0.008149582950063676 0.010878930150616459 9.118570252679983e-07 6.040073251589189 0.08362585952171764 LYSILQGDS(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 1 LYSILQGDSPTK 12 0 O15042-2;O15042;O15042-3 O15042-2 U2SURP U2 snRNP-associated SURP motif-containing protein 1 LYSILQGDS(0.812)PT(0.188)K 169.3 0.0010052 6699300.0 21482.0 22415.0 24445.0 18898.0 22298.0 23624.0 25025.0 25982.0 20258.0 19315.0 True False 28312.829146642125 29660.21040078452 24120.84332792075 14541.35807118948 19202.307591496745 22146.78754544775 27252.176520151264 21967.07890696391 21328.79652247332 18638.787729028434 1.5190273937476706 1.5913164971878022 1.2941208236603525 0.780166515257989 1.030233718558352 1.1882096554464154 1.4621217278904979 1.178568007014315 1.1443231626730428 1.0 14.186020409381058 -5.441405470069148 4.651734028988021 1.1274641759082573 1.5449313884069173 0.5314177792717423 0.16453174105041307 0.18941996011085985 7.251465197060004 0.04852020197926553 0.10365738917874352 3.619049555542211e-06 5.441405470069148 0.41746721249866003 LYSILQGDS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LYSILQGDSPTK 12 0 O15042-2;O15042;O15042-3 O15042-2 U2SURP U2 snRNP-associated SURP motif-containing protein 1 LYSILQGDS(0.975)PT(0.025)K;LYSILQGDS(0.89)PT(0.11)K 121.18 0.00045855 2987900.0 41074.0 56011.0 47261.0 49847.0 52836.0 41193.0 50804.0 44612.0 34299.1 36150.5 True False 48027.01695152128 61571.4019161967 48387.88147834059 47054.23419615442 42483.16508639958 39032.76656386795 45991.477330892085 43440.98227032119 34800.659449977866 42704.29948279947 1.1246412547023679 1.4418080301492022 1.1330915637155075 1.1018617508316002 0.9948217299176408 0.9140242794426273 1.07697533709496 1.0172507873081595 0.8149216793497561 1.0 15.382093707714901 -5.80691769439484 1.6926921077669481 0.9730372813831637 1.2815433752299012 0.5884017036260616 0.10110395665753609 0.24324567896104057 1.4205619272853087 0.03134923379085032 0.06359957683052508 1.5598480904564278e-06 5.80691769439484 0.30850609384673755 LYSILQGDS(ph)PTKWR ddPTM_PC-9_AZD4547_30min_R2 1 LYSILQGDSPTKWR 14 1 O15042-2;O15042;O15042-3 O15042-2 U2SURP U2 snRNP-associated SURP motif-containing protein 1 LYS(0.004)ILQGDS(0.938)PT(0.059)KWR 51.798 0.044282 4972200.0 7752.8 4422.0 10539.0 12435.0 9431.4 8235.0 9057.1 11745.0 8062.5 7375.0 True False 10218.029131742253 5851.32502307692 10399.245973939733 9568.302868834853 8122.012907814263 7720.064148186678 9863.164354072416 9930.080123250362 8488.667290080024 7116.80349477529 1.4357610322167371 0.8221844297615629 1.4612242675485145 1.3444663571024968 1.1412445086866503 1.0847656751875001 1.385898087717798 1.3953005911348264 1.1927640402481072 1.0 12.797013686285693 -13.54925315242998 5.987682100589283 1.25104349844672 1.2340519335347004 0.0 0.20262354313064998 0.0 0.0 0.0 0.044608532555220064 2.823233818044522e-14 13.54925315242998 -0.016991564912019586 LYSILQGDSPT(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LYSILQGDSPTK 12 0 O15042-2;O15042;O15042-3 O15042-2 U2SURP U2 snRNP-associated SURP motif-containing protein 1 LYSILQGDS(0.217)PT(0.783)K 142.39 0.00019880000000000003 4584000.0 25290.0 36508.0 28089.0 30005.0 28666.0 23204.0 25411.0 15874.0 17376.0 19148.0 True False 29571.097499731542 40132.27296703346 28758.74828812572 28323.917127522494 23049.103080602796 21987.14139169257 23003.88612029169 15457.32431989327 17630.091127837622 22619.380824515407 1.3073345256065412 1.774242773415671 1.271420668463052 1.2521968371841716 1.0189979672485838 0.9720487736721068 1.0169989310830094 0.6833663768170111 0.779424125912842 1.0 14.465271817558564 -6.097324861355089 0.8805720694947909 0.8408837169554921 1.5624214445688334 0.7385554025972119 0.1504466912795679 0.30757321054162823 0.49400254821251016 0.07053465340596494 0.14251374673354789 7.992361859688961e-07 6.097324861355089 0.7215377276133412 LYSILQGDSPT(ph)KWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LYSILQGDSPTKWR 14 1 O15042-2;O15042;O15042-3 O15042-2 U2SURP U2 snRNP-associated SURP motif-containing protein 1 LYS(0.001)ILQGDS(0.174)PT(0.825)KWR 67.29899999999999 0.024968999999999998 4243900.0 15660.0 12174.0 14136.0 23076.0 20112.0 17037.0 17090.0 20522.0 18936.0 14754.0 True False 18310.928700901382 13382.55426483689 14473.05585107853 21783.126533401413 16171.197975200019 16143.549728075603 15471.111479114754 19983.319244856346 19212.903176607568 17428.783407400253 1.0506142782821302 0.7678421351632991 0.8304111372990772 1.2498363209994514 0.9278443364172932 0.9262579808766835 0.8876759276580216 1.1465699456894645 1.1023662826890015 1.0 14.089184247156036 -6.152378465283413 0.42670245714443567 1.0555933076244177 0.8798712590951463 0.07734483037927953 0.13639715243293873 4.711517763324323 1.477537215647153 0.1335078100856671 0.37562641470167635 7.040792327374636e-07 6.152378465283413 -0.17572204852927142 LYSNAYLNDLAGCIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 LYSNAYLNDLAGCIK 15 0 P00352;Q5SYQ7;Q5SYQ9;Q5SYQ8 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ; 125.03 0.00012698 5559900.0 23504.0 27204.0 23937.0 28802.0 30553.0 31196.0 31405.0 28596.0 27782.0 27434.0 False True 27482.762974839487 29904.633335027334 24507.748861578024 27188.31731734388 24566.358976545638 29560.02684258063 28430.091047489674 27845.38529996648 28188.259191619756 32407.567032575487 0.8480353661604502 0.9227669977498697 0.7562353828333762 0.8389496591957887 0.7580439146157435 0.9121334783591573 0.8772670598478519 0.8592247999356698 0.8698048564795203 1.0 14.984043095305765 -6.796191521118681 24.999969247315352 0.8932364285696798 0.8272246625244142 0.31065172901012916 0.05765482001589897 272.4344366548018 195981.74055000636 0.020185201160985034 0.017802395023475227 1.5988527891591622e-07 6.796191521118681 -0.0660117660452656 LYSNAYLNDLAGCIK ddPTM_PC-9_Lapatinib_30min_R1 2 LYSNAYLNDLAGCIK 15 0 P00352;Q5SYQ7;Q5SYQ9;Q5SYQ8 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ; 179.46 0.00013639 35806000.0 72267.0 61477.0 70277.0 63356.0 69237.0 64069.0 57043.0 61316.0 62782.0 63825.0 False True 71236.45932785515 61334.65378363563 64499.096337065 68015.41158942028 65164.61578517936 61328.9182221336 59996.40742645743 64164.96520506311 55710.83003623109 74857.06620853335 0.9516330646649699 0.8193569009607242 0.8616300317913396 0.9086037569245113 0.8705205678732693 0.8192802807858692 0.8014795458229984 0.8571664433964767 0.7442294075623328 1.0 16.191850886919838 -6.654683887956735 5.6715050558877484 0.832992115822341 0.880053442452527 0.0590871699479566 0.0689338472499384 0.5135786928391491 23.900870185082912 0.021618351020106362 0.021521994523260948 2.2147061520416722e-07 6.654683887956735 0.04706132663018603 LYSSEES(ph)RPYTNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LYSSEESRPYTNK 13 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YF61;A0A087X209;Q9BVE2;A0A2R8YEB7;A0A2R8Y644 Q14004 CDK13 Cyclin-dependent kinase 13 1 LYSS(0.005)EES(0.993)RPYT(0.001)NK 91.307 0.024997 11824000.0 18897.0 17129.0 24457.0 23755.0 21448.0 18667.0 20581.0 20925.0 20070.0 15973.0 True False 22095.888867237136 18829.45391838271 25040.147633689012 22424.08436474911 17245.41836575626 17688.0696586246 18631.41868646348 20375.74092187015 20363.485781290336 18868.778457801567 1.1710291112195064 0.9979158937338312 1.3270677638030035 1.1884226853846784 0.913965808879689 0.9374252656674347 0.9874205014453414 1.0798653960264983 1.079215902970696 1.0 14.203713407155762 -6.246668457242906 24.675969555386835 0.9999194889540587 1.1698778738751392 0.47252621833007313 0.08874338999913027 670.4766668596103 1120082.6485077655 0.027857981270193347 0.03579986467742477 5.666717242156337e-07 6.246668457242906 0.1699583849210805 LYSSEES(ph)RPYTNK ddPTM_PC-9_Lapatinib_30min_R1 1 LYSSEESRPYTNK 13 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YF61;A0A087X209;Q9BVE2;A0A2R8YEB7;A0A2R8Y644 Q14004 CDK13 Cyclin-dependent kinase 13 1 LYS(0.001)SEES(0.972)RPYT(0.027)NK 164.93 0.0015484000000000001 23345000.0 27418.0 25026.0 24619.0 19477.0 17534.0 24408.0 23268.0 17228.0 22042.0 12685.0 True False 27027.0142921546 24968.05383459284 22594.920852088224 20909.403553367316 16502.684593170336 23364.126737826988 24472.70318880162 18028.475773906106 19559.39784744999 14877.585348299965 1.8166263986677735 1.6782329423803908 1.5187223143485515 1.4054299178163745 1.10923138445017 1.5704246482778044 1.6449378454816308 1.2117877566715616 1.3146890029224405 1.0 13.860852773689295 -1.5228787452803376 0.09906435182371555 0.8310158648308448 3.4048528061669683 0.5587638606940168 0.16726971422485448 115.81603712378185 0.8173826557052561 2.4513204383404683 40.49990999098074 0.029999999999999995 1.5228787452803376 2.5738369413361237 LYSSEESRPYT(ph)NK ddPTM_PC-9_AZD4547_30min_R2 1 LYSSEESRPYTNK 13 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YF61;A0A087X209;Q9BVE2;A0A2R8YEB7;A0A2R8Y644 Q14004 CDK13 Cyclin-dependent kinase 13 1 LYSSEESRPYT(1)NK 154.13 0.0016515 15901000.0 23191.0 19195.0 31555.0 30697.0 25700.0 17546.0 26668.0 16419.0 17432.0 24311.0 True False 30565.25559723383 25399.40837131646 31136.56008232926 23620.280913922274 22131.998614291257 16448.845846276075 29041.400337238516 13881.820821085372 18353.419931866672 23459.8792896925 1.3028735237637474 1.0826742992866174 1.3272259289078967 1.0068372740647582 0.9433978044386327 0.7011479318865531 1.2379177223643412 0.591726012298136 0.7823322407260024 1.0 14.517907969701461 -6.03775136093282 2.538379336329941 0.8630653185157188 1.2219810856742692 0.4491013876304072 0.17702070899926745 0.26385636251864897 3.3870557757091717 0.05413311092185961 0.07982556358594667 9.167451880895612e-07 6.03775136093282 0.35891576715855045 LYSSGS(ph)STPTGLAGGSR ddPTM_PC-9_AZD4547_30min_R2 1 LYSSGSSTPTGLAGGSR 17 0 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 LYS(0.208)S(0.208)GS(0.579)S(0.002)T(0.002)PT(0.001)GLAGGSR 200.63 1.2521e-12 7195000.0 11380.0 15265.0 14638.0 13559.0 14291.0 14654.0 14060.0 13838.0 13318.0 12110.0 True False 14998.603281295367 20199.112726655174 14443.890555700713 10433.182034461752 12306.941330616208 13737.683063452052 15311.312762170906 11699.655065605668 14021.962290764135 11686.032585997124 1.2834640987795598 1.7284833477923818 1.235996087586493 0.8927907703221186 1.05313255290449 1.1755643296693639 1.3102233499261162 1.0011657061118302 1.1998907402984702 1.0 13.512497596843456 -5.493705488662365 9.883248178181555 1.0987032650411082 1.5006066661936377 0.547491925831122 0.14956706018640542 0.3622981608812529 119.26242156967098 0.038489288252249676 0.07793011530208199 3.2084443531001857e-06 5.493705488662365 0.40190340115252954 LYTCRLCHDNNEDHQLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LYTCRLCHDNNEDHQLDR 18 1 Q96PM5-6;Q96PM5-2;Q96PM5;D6RAF6;H0YAI4;Q96PM5-5;Q96PM5-3;Q96PM5-4 Q96PM5-6 RCHY1 RING finger and CHY zinc finger domain-containing protein 1 0 43.023999999999994 0.034307 7171800.0 33537.0 30089.0 36016.0 59260.0 23000.0 58033.0 47128.0 25403.0 50441.0 48316.0 False True 39214.15171405681 33076.03706872657 36874.75803144062 55939.854323512234 18493.315106881473 54989.64731874221 42663.694662827394 24736.198166703347 51178.60420000328 57075.308330754415 0.6870598313163503 0.5795156966485261 0.6460719899706798 0.9801060381371545 0.3240160350901959 0.9634577355250419 0.7474982774615783 0.4333957869023813 0.8966855492645012 1.0 15.800579127710312 -8.508624173717502 23.02745410805759 1.000000052843039 0.6766909404001106 0.256528913655932 0.19322778730730625 286.2395858804684 462402.8253431444 0.1771141802587043 0.045730684709032604 3.1001008792516504e-09 8.508624173717502 -0.3233091124429285 LYTLVLTDPDAPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 LYTLVLTDPDAPSR 14 0 P30086 P30086 PEBP1 Phosphatidylethanolamine-binding protein 1;Hippocampal cholinergic neurostimulating peptide 0 138.76 3.5015e-05 0.0 9025.5 8249.3 21423.0 17961.0 19814.0 20396.0 14036.0 11545.0 17298.0 18225.0 False True 10553.33888824939 9068.235986275578 21933.805567179937 16954.70340034766 15931.588935989115 19326.397854894047 12706.408468160022 11241.955982938633 17550.950525399112 21529.04823097938 0.4901906844661895 0.42120933024929424 1.018800521595661 0.787526843660026 0.7400043311280357 0.8976893751895723 0.590198337234251 0.5221761715765 0.8152218498978531 1.0 14.39399692094046 -14.295446902661213 0.035576252382815865 2.0406936793087347 1.1710062168735839e-05 0.20085229142134686 0.18115777482830708 2238.38618003054 6.170170724893819 294.0306911826693 104.33641136415804 5.064692672490855e-15 14.295446902661213 -2.040681969246566 LYTLVLTDPDAPSR ddPTM_PC-9_Lapatinib_30min_R1 2 LYTLVLTDPDAPSR 14 0 P30086 P30086 PEBP1 Phosphatidylethanolamine-binding protein 1;Hippocampal cholinergic neurostimulating peptide 0 ; 187.31 2.0481999999999998e-05 15269800.0 42012.0 41051.0 49958.0 43118.0 48639.0 51824.0 48735.0 39075.0 47698.0 42050.0 False True 41412.90117594279 40955.9489316659 45850.646083456806 46289.04155743141 45778.14964795326 49607.60832764444 51258.25983781361 40890.56715030073 42325.74895779283 49318.28647189699 0.8397068134056336 0.8304414419386571 0.9296885468554115 0.9385776528105507 0.9282185761672599 1.0058664214928132 1.0393357820130689 0.829115731212628 0.8582161300740099 1.0 15.589835054767862 -5.295378734951438 4.684600424932567 0.9410137521328705 0.833992890050435 0.3280762194228083 0.06082746097203348 0.2353504734438752 12.965555799307788 0.01736933799393275 0.0403906037958765 5.065487698933616e-06 5.295378734951438 -0.10702086208243555 LYTSAPNT(ph)SQGK ddPTM_PC-9_AZD4547_30min_R2 1 LYTSAPNTSQGK 12 0 Q5QJE6;J3KP30 Q5QJE6 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 LYT(0.003)S(0.065)APNT(0.466)S(0.466)QGK 83.617 0.026473000000000003 4505200.0 22471.0 27058.0 30007.0 24187.0 39546.0 39333.0 31679.0 34263.0 29174.0 30055.0 True False 29616.310574164192 35803.96935197089 29609.087573774494 18611.060835424916 34055.720513648324 36873.50129212226 34498.36962964525 28968.440635413128 30716.078080098563 29002.783598030033 1.021154072127609 1.2345011378288122 1.020905027053529 0.6416991242416139 1.174222481043561 1.2713780098896035 1.1894847786951213 0.998815873569486 1.0590734498389631 1.0 14.823903751870747 LYVHEAVK ddPTM_PC-9_Lapatinib_30min_R1 2 LYVHEAVK 8 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 91.853 0.0092458 0.0 91626.0 87890.0 92676.0 80957.0 91235.0 92147.0 91768.0 78313.0 90086.0 79768.0 False True 90319.39643784954 87686.49610494541 85056.53701970537 86910.84784463531 85868.73667491136 88206.08761514857 96519.29801572744 81951.70787566208 79939.56603236447 93555.79251582116 0.9654067803719977 0.9372642115143945 0.9091530810913875 0.9289734553842605 0.9178345281014016 0.9428180259413879 1.0316763443525436 0.8759661552950159 0.8544587553875506 1.0 16.51353936038202 -10.617786159590242 4.148071746395237 1.0000117267123005 0.9304217592961359 0.17594104989512904 0.04585369419314404 33862945.132385306 4591.799658227947 3961.4722553657666 0.011519048295166477 2.4110923239350867e-11 10.617786159590242 -0.06958996741616463 MAAVVLPPTAALSSLFPAS(ph)QR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MAAVVLPPTAALSSLFPASQR 21 0 Q8N988-2 Q8N988-2 1 MAAVVLPPT(0.002)AALS(0.088)S(0.088)LFPAS(0.822)QR 47.618 0.041612 4992700.0 23571.0 20689.0 21565.0 54744.0 45735.0 44214.0 40455.0 34449.0 28821.0 22503.0 True False 27561.104751529165 22742.86719116235 22079.19138571793 51676.87116244268 36773.55506144457 41895.34000570137 36622.809531163664 33544.75025173263 29242.45260102487 26582.615766350013 1.0368093566780507 0.8555541482848251 0.8305876133404145 1.9440100107777427 1.3833685663092232 1.5760427933031027 1.377697734980738 1.2619055455857633 1.100059258955315 1.0 14.698195454346529 -5.693884072369955 24.99999919279795 1.3970265731442113 0.9024370413305509 0.4259605409609162 0.24925795080356275 48.94455572500528 18111.823070824423 0.06742244936746206 0.11677908290041421 2.023559261807529e-06 5.693884072369955 -0.4945895318136604 MAAVVLPPTAALSSLFPAS(ph)QR ddPTM_PC-9_Lapatinib_30min_R1 1 MAAVVLPPTAALSSLFPASQR 21 0 Q8N988-2 Q8N988-2 1 MAAVVLPPT(0.001)AALS(0.044)S(0.044)LFPAS(0.911)QR 47.732 0.041116 13092000.0 74078.0 54532.0 70587.0 63221.0 73406.0 75727.0 68272.0 53781.0 77062.0 45951.0 True False 73021.63413575856 54405.73450443609 64783.60933369959 67870.48323907348 69088.40340174876 72488.3327382589 71806.79010253849 56279.861597193165 68382.46606116462 53893.56912414125 1.3549229587588962 1.0095032744837347 1.2020656710353264 1.259342892706495 1.2819415103610403 1.3450275035836932 1.3323814189617875 1.0442778704738447 1.2688427798064161 1.0 15.717825512523028 -10.85123999541204 4.617866631188986 0.9998191270496035 1.2285134641802429 0.2751271287336511 0.11330604580112887 0.000214282665694081 3.1165838827995675e-05 0.11141812517998083 0.027001593897938873 1.4085102266819073e-11 10.85123999541204 0.22869433713063936 MAEESSSSSSSS(ph)SPTAATSQQQQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MAEESSSSSSSSSPTAATSQQQQLK 25 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 MAEES(0.019)S(0.019)S(0.019)S(0.019)S(0.019)S(0.08)S(0.08)S(0.243)S(0.243)PT(0.039)AAT(0.164)S(0.056)QQQQLK;MAEESSS(0.001)S(0.004)S(0.012)S(0.047)S(0.16)S(0.696)S(0.079)PT(0.002)AATSQQQQLK 112.75 5.8814e-08 20254500.0 32607.2 31335.8 44724.0 42609.7 48859.0 45763.2 42800.0 43404.0 40251.0 36535.6 True False 38126.95493844393 34446.611132912396 45790.38977671452 40222.41665151125 39285.42968726617 43363.297230490636 38745.674154833905 42264.690990339404 40839.59472758933 43159.215064349555 0.8834024178057311 0.7981287676699672 1.0609643782548392 0.9319543136162325 0.9102443042277845 1.0047285884564119 0.8977381561982731 0.9792738567493308 0.9462543437525053 1.0 15.39738100635249 -5.243596946021341 24.998416643450607 0.9613361843641072 0.8407655860641999 0.5004054328688783 0.05000698221692833 659.1951254963335 923572.2821513376 0.012068709706803887 0.0317862232136895 5.70693668022669e-06 5.243596946021341 -0.12057059829990724 MAEESSSSSSSS(ph)SPTAATSQQQQLK ddPTM_PC-9_Lapatinib_30min_R1 2 MAEESSSSSSSSSPTAATSQQQQLK 25 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 MAEESSS(0.001)S(0.003)S(0.014)S(0.049)S(0.171)S(0.614)S(0.145)PT(0.002)AATSQQQQLK;MAEESS(0.001)S(0.001)S(0.003)S(0.01)S(0.077)S(0.077)S(0.412)S(0.412)PT(0.007)AATSQQQQLK 115.34 6.1563e-09 19410500.0 32106.0 25585.0 32372.0 29430.0 29098.0 34580.0 32276.0 30030.0 35964.0 29842.0 True False 31648.1625524807 25525.759504437723 29710.49911953366 31594.380375601995 27386.512848869086 33101.09400991711 33947.09335231913 31425.303429904838 31913.35560229071 35000.149938034476 0.9042293421174408 0.7293042901138836 0.8488677669134045 0.9026927150751589 0.7824684436311031 0.9457414916370496 0.9699127978714458 0.8978619658927555 0.9118062539386621 1.0 15.095073482018352 -6.7766745258554675 24.987712269141845 0.9402339254710087 0.832419582189388 0.5033046118871305 0.05529923436927924 209.91678141955626 344289.9182675392 0.019207711700569532 0.017002025287155574 1.6723434523469465e-07 6.7766745258554675 -0.10781434328162065 MAEESSSSSSSSS(ph)PTAATSQQQQLK ddPTM_PC-9_AZD4547_30min_R2 2 MAEESSSSSSSSSPTAATSQQQQLK 25 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 MAEESSSSSS(0.002)S(0.007)S(0.172)S(0.803)PT(0.014)AAT(0.001)SQQQQLK;MAEESSSSSSS(0.002)S(0.158)S(0.839)PT(0.001)AATSQQQQLK 154.17 1.0082000000000001e-07 30270000.0 29612.0 23974.6 33815.0 44644.0 39307.0 33084.0 29928.0 37637.0 32609.0 37968.0 True False 39028.00003213698 31723.92060114423 33366.5910056715 34352.01554292428 33849.90153820805 31015.252249982783 32591.534021781717 31821.06646222001 34332.64516740706 36638.75187655976 1.0652109592495638 0.8658570223141286 0.9106912571172578 0.9375869477939706 0.9238824961137411 0.8465149783070338 0.8895372345539063 0.8685084734717192 0.9370582623304897 1.0 15.161082737455713 -4.7531661206372435 24.991724967451518 0.9036134802925889 1.06521125912601 0.5453318012471158 0.04259147633850988 223.76140292395863 675882.1829104079 0.010175472112573485 0.11272565551070282 1.7653624282082485e-05 4.7531661206372435 0.16159777883342097 MAEESSSSSSSSS(ph)PTAATSQQQQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MAEESSSSSSSSSPTAATSQQQQLK 25 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 MAEESSSSSSS(0.001)S(0.21)S(0.781)PT(0.007)AATSQQQQLK 179.44 3.4865e-15 12543000.0 30749.0 30040.0 39269.0 43991.0 39214.0 40462.0 41873.0 33829.0 35472.0 32498.0 True False 35954.19837956683 33022.17267255627 40205.32188851182 41526.326890746284 31530.298200054385 38340.10149071992 37906.4863057327 32941.02459478831 35990.71089356906 38389.630145973555 0.9365601659316282 0.860184704749487 1.0472964114432528 1.0817068758632393 0.8213233125758935 0.9987098428647188 0.9874147305299963 0.8580709027290091 0.9375112694943194 1.0 15.228429040564212 -6.255876702044963 24.998679689943963 0.9326642838508038 0.9774803874376577 0.08080445563844552 0.07813346867372746 1480.3612860861626 6652746.932081131 0.02432236342229432 0.030564503110868405 5.547831957887192e-07 6.255876702044963 0.04481610358685395 MAEESSSSSSSSS(ph)PTAATSQQQQLK ddPTM_PC-9_Lapatinib_30min_R1 1 MAEESSSSSSSSSPTAATSQQQQLK 25 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 MAEESSSSSSS(0.002)S(0.087)S(0.903)PT(0.007)AATSQQQQLK 105.44 0.00044419 0.0 33570.0 30767.0 36140.0 28650.0 30078.0 31968.0 25342.0 27601.0 33175.0 25961.0 True False 33091.285644015974 30695.760901818834 33168.70870443428 30757.016573598274 28308.87117562321 30600.803161047723 26654.084760641676 28883.443222404356 29438.482151762702 30448.324259141915 1.0868015383171876 1.0081264453364007 1.0893443074942157 1.0101382365685914 0.929734948126863 1.0050077928955328 0.8753875758085097 0.9486053477551326 0.9668342303903305 1.0 14.894075210323058 -6.040353664619129 4.197650148400015 0.9508007073928807 1.0560034304967978 0.5874489737606482 0.04025406246980916 0.1466019015119284 5.644181384351574 0.011586513669801133 0.015995687729412338 9.11268452142362e-07 6.040353664619129 0.1052027231039171 MAEGEDMQTFT(ph)SIMDALVRIS(ph)T(ph)SMK ddPTM_PC-9_Lapatinib_30min_R1 1 MAEGEDMQTFTSIMDALVRISTSMK 25 1 Q5VT61;Q7Z4K8-4;Q7Z4K8-2;Q7Z4K8 Q5VT61 TRIM46 Tripartite motif-containing protein 46 3 MAEGEDMQT(0.1)FT(0.474)S(0.474)IMDALVRIS(0.65)T(0.651)S(0.651)MK 40.381 0.032612999999999996 2153800.0 5588.6 6285.7 6952.8 5786.3 6663.4 7007.4 8362.9 7158.8 6227.3 6653.2 True False 5508.905539176281 6271.1458478422555 6381.167622584142 6211.843804530954 6271.471912748443 6707.709837047232 8795.89004201603 7491.42398248427 5525.915897623868 7803.196755168257 0.7059806015435395 0.8036636835651638 0.8177632607248729 0.7960639721684181 0.8037054696326459 0.8596104965063893 1.1272162317565921 0.9600455066729552 0.7081605233091056 1.0 12.929849562227494 -7.009222215874061 15.625302040299413 0.9523674458532221 0.7931124681507291 0.3688421242319686 0.10048323676268901 3.747842486961855 6349.090257616951 0.03755241656519952 0.031199274342460483 9.789889370253798e-08 7.009222215874061 -0.15925497770249297 MAGNEALS(ph)PTSPFR ddPTM_PC-9_AZD4547_30min_R2 1 MAGNEALSPTSPFR 14 0 Q86WR7;Q86WR7-2;D3DRR9 Q86WR7 PROSER2;C10orf47 Proline and serine-rich protein 2 1 MAGNEALS(0.481)PT(0.481)S(0.037)PFR 65.528 0.034101 140380000.0 56731.0 55833.0 89580.0 116800.0 81616.0 80485.0 55791.0 94033.0 65675.0 68594.0 True False 74770.27792189515 73879.92537617678 88392.11066946786 89873.56454201143 70285.02719470816 75452.26022669146 60756.29091851187 79502.36051337591 69146.44642183022 66192.54493838879 1.1295875992000368 1.1161366502065044 1.3353786404759351 1.3577596181815437 1.0618269362528454 1.139890606969735 0.9178721104478319 1.2010772600959176 1.0446258938403241 1.0 16.014381119451038 -6.293383438702809 24.378970007469494 1.0677358812624052 1.2334359199320932 0.41698941255534205 0.1004961764485452 528.5112430483465 403346.0025704154 0.032340259571763494 0.036674050045193425 5.088813811648723e-07 6.293383438702809 0.16570003866968808 MAGNEALS(ph)PTSPFR ddPTM_PC-9_Lapatinib_30min_R1 2 MAGNEALSPTSPFR 14 0 Q86WR7;Q86WR7-2;D3DRR9 Q86WR7 PROSER2;C10orf47 Proline and serine-rich protein 2 1 MAGNEALS(0.991)PT(0.008)S(0.001)PFR;MAGNEALS(0.469)PT(0.469)S(0.061)PFR 178.01 7.9901e-05 21340300.0 40815.8 38697.0 31430.2 32673.1 69012.0 75896.0 76955.0 73785.0 95390.0 76262.0 True False 40233.75920729901 38607.39947403659 28846.130280080542 35075.98876826647 64952.84984281237 72650.10500221717 80939.35335629314 77213.3204653857 84646.17369876846 89443.78508727242 0.44982174186883944 0.4316387039788895 0.3225056973151873 0.3921568025552809 0.7261862831435 0.8122431863916619 0.9049186958861222 0.8632608782158182 0.9463617132948609 1.0 16.448693621074604 -6.471809081284704 1.9539727226642454 0.9062137034029994 0.3890104373432028 0.9490008017555577 0.05541922037345185 0.07084086142312426 0.5403246901099064 0.02100025320648377 0.02359264739906617 3.374356149775705e-07 6.471809081284704 -0.5172032660597967 down MAGNEALSPT(ph)SPFR ddPTM_PC-9_AZD4547_30min_R2 3 MAGNEALSPTSPFR 14 0 Q86WR7;Q86WR7-2;D3DRR9 Q86WR7 PROSER2;C10orf47 Proline and serine-rich protein 2 1 MAGNEALS(0.081)PT(0.905)S(0.015)PFR;MAGNEALS(0.432)PT(0.457)S(0.11)PFR;MAGNEALS(0.031)PT(0.866)S(0.103)PFR 176.42 5.8903e-05 15329700.0 49609.5 52488.7 61253.0 80449.0 71035.0 61466.0 49701.0 62471.0 53286.0 60620.0 True False 65384.28905829727 69454.64580252767 60440.745198000805 61902.725974659945 61173.01640335332 57622.521303271686 54124.2927164051 52817.542390768314 56102.589174474946 58497.71225129198 1.1177238654636992 1.1873053343379885 1.033215537359171 1.0582076391080193 1.04573348339793 0.9850388858924827 0.9252377679985205 0.9028992820074222 0.9590561239980092 1.0 15.836092583933457 -6.0684961514722655 0.7174777560861884 0.9373913506033276 1.1592827269984491 0.7544699160545096 0.04081444624696294 0.4014349522445648 0.4165866189732881 0.023597451651419757 0.05504838287873998 8.540904159606896e-07 6.0684961514722655 0.22189137639512158 MAGNEALSPT(ph)SPFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 MAGNEALSPTSPFR 14 0 Q86WR7;Q86WR7-2;D3DRR9 Q86WR7 PROSER2;C10orf47 Proline and serine-rich protein 2 1 MAGNEALS(0.201)PT(0.789)S(0.01)PFR;MAGNEALS(0.038)PT(0.95)S(0.012)PFR;MAGNEALS(0.001)PT(0.967)S(0.032)PFR 144.4 0.00066944 91483000.0 135559.0 130019.0 170993.0 202425.0 340349.0 443740.0 528820.0 514580.0 437750.0 339745.0 True False 158506.46128770662 142926.4270543639 175070.1216145638 191083.7835207042 273660.05666573904 420469.4932403747 478726.34127474885 501072.82024257694 444151.26560836256 401338.07908005913 0.3949449841665477 0.3561247599080995 0.4362160750254668 0.47611675413084015 0.6818691545367894 1.0476690729276632 1.1928256156806198 1.2485055527029187 1.1066761136307801 1.0 18.614458520396944 -6.615697746324881 1.7449671133268483 1.163410839298388 0.3994304171128847 0.9619326001978094 0.0665317613692844 0.059327094381070304 0.37046433093327136 0.02629278609875618 0.02678178613038987 2.4227145842178885e-07 6.615697746324881 -0.7639804221855033 down MAGNEALSPT(ph)SPFR ddPTM_PC-9_Lapatinib_30min_R1 4 MAGNEALSPTSPFR 14 0 Q86WR7;Q86WR7-2;D3DRR9 Q86WR7 PROSER2;C10orf47 Proline and serine-rich protein 2 1 MAGNEALS(0.019)PT(0.65)S(0.331)PFR;MAGNEALS(0.089)PT(0.865)S(0.046)PFR;MAGNEALS(0.395)PT(0.537)S(0.068)PFR;MAGNEALS(0.081)PT(0.908)S(0.012)PFR 181.58 7.2325e-05 57702800.0 101888.3 90686.0 102257.5 90655.7 178257.0 219890.0 224863.0 189767.0 256286.0 188783.0 True False 100435.35415797407 90476.02213873136 93850.2830753652 97322.82259654973 167772.27372674627 210485.81728862578 236505.30587689107 198584.26759849308 227420.3718687764 221413.89001246422 0.4536090944986341 0.40862848366756993 0.42386809188024294 0.43955156829172304 0.7577314761838191 0.9506441410553635 1.0681593005008732 0.8968916430099034 1.0271278457551785 1.0 17.756386204340963 -6.463327734718525 2.141556554608695 0.9915997015827379 0.4209896373268979 0.9730710260441416 0.04369506811343661 0.04576620253127104 0.4173125954712238 0.015543990462162545 0.017447782460205893 3.4409016956305174e-07 6.463327734718525 -0.57061006425584 down MAGNEALSPTS(ph)PFR ddPTM_PC-9_AZD4547_30min_R2 3 MAGNEALSPTSPFR 14 0 Q86WR7;Q86WR7-2;D3DRR9 Q86WR7 PROSER2;C10orf47 Proline and serine-rich protein 2 1 MAGNEALS(0.002)PT(0.043)S(0.955)PFR;MAGNEALSPT(0.052)S(0.947)PFR;MAGNEALS(0.023)PT(0.013)S(0.964)PFR 102.63 0.001245 76936800.0 346686.0 309311.0 457152.0 588803.0 534838.0 440169.0 436977.0 550005.0 467551.0 436154.0 True False 456924.93648323143 409289.7318437234 451089.86578219006 453063.56526566745 460584.9756758876 412645.16284677474 475867.10646338324 465014.36510756274 492264.79133571516 420884.3812149465 1.0856305362633045 0.972451699590863 1.0717667034353968 1.0764561135716912 1.0943266042477968 0.9804240339249748 1.1306361739766175 1.1048506094838406 1.1695962437824807 1.0 18.683064447499405 -7.296049769969502 24.995767238996862 1.1100083136745178 1.048098526360116 0.17828969410099826 0.055961565793082105 956.0022429737188 690425.1168947471 0.022468231272824733 0.015148424005117709 5.057666980256974e-08 7.296049769969502 -0.06190978731440189 MAGNEALSPTS(ph)PFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 MAGNEALSPTSPFR 14 0 Q86WR7;Q86WR7-2;D3DRR9 Q86WR7 PROSER2;C10orf47 Proline and serine-rich protein 2 1 MAGNEALS(0.052)PT(0.062)S(0.886)PFR;MAGNEALS(0.025)PT(0.014)S(0.962)PFR;MAGNEALS(0.01)PT(0.053)S(0.937)PFR;MAGNEALSPT(0.017)S(0.983)PFR 98.676 0.0021086 59594400.0 240113.0 238820.0 245305.0 259181.0 422096.0 406788.0 458363.0 508764.0 411295.0 343161.0 True False 280759.3884520775 262528.4712936045 251154.00152439257 244659.92884613975 339389.3188414886 385455.321170653 414943.53837925615 495409.4840800168 417309.4112813052 405373.3728390177 0.6925945492812943 0.6476214001304424 0.619562157636168 0.603542179232624 0.8372264721399628 0.9508649235422905 1.0236082737087888 1.2221066238525595 1.0294445546797855 1.0 18.628891802179155 -6.709050133158193 1.5469262276948097 1.0878585212074467 0.636856162046438 0.8962069184708247 0.06536267388126879 0.10923162647636153 0.542931806682985 0.028368265204047675 0.02687763002152182 1.9541138679349821e-07 6.709050133158193 -0.4510023591610087 MAGNEALSPTS(ph)PFR ddPTM_PC-9_Lapatinib_30min_R1 3 MAGNEALSPTSPFR 14 0 Q86WR7;Q86WR7-2;D3DRR9 Q86WR7 PROSER2;C10orf47 Proline and serine-rich protein 2 1 MAGNEALS(0.028)PT(0.054)S(0.918)PFR;MAGNEALS(0.013)PT(0.014)S(0.973)PFR;MAGNEALS(0.073)PT(0.225)S(0.702)PFR 99.796 0.0021166 32311500.0 111765.0 131942.0 140242.0 114908.0 195428.0 238255.0 197211.0 211505.0 248608.0 252661.0 True False 110171.21060480928 131636.49640549204 128711.844109775 123358.71764185095 183933.30926623094 228065.38904953195 207421.620619166 221332.29443696328 220607.14908170077 296333.1172003799 0.37178163428258243 0.44421797215624637 0.43434849714330204 0.41628394020650755 0.6206977843176926 0.7696250463133844 0.6999609850521968 0.7469036755932305 0.7444566141168981 1.0 18.1768603405298 -6.368388559003 0.22749572577969573 1.038789522714882 0.10079227319119899 0.905463638859964 0.05938355765055978 1.6688701920650717 0.1579088249791992 0.14460010062262169 0.4678158167422234 4.2816527371878745e-07 6.368388559003 -0.937997249523683 down MAGS(ph)RLET(ph)VGS(ph)IFS(ph)RTR ddPTM_PC-9_AZD4547_30min_R2 1 MAGSRLETVGSIFSRTR 17 2 J3QLR8;Q9Y3D9 J3QLR8 MRPS23 28S ribosomal protein S23, mitochondrial 4 MAGS(1)RLET(1)VGS(0.889)IFS(0.555)RT(0.555)R 44.691 0.040006 10770000.0 14895.0 16963.0 24408.0 31879.0 24655.0 24848.0 17157.0 28360.0 17366.0 25968.0 True False 19631.300164753495 22445.958020455397 24084.33397209611 24529.78907564025 21232.078826278244 23294.25063195418 18683.939762486916 23977.613647967668 18283.93130660834 25058.86822404405 0.7834072947443497 0.8957291215138935 0.9611102048490413 0.9788865505148333 0.8472880194128644 0.9295811137074134 0.7456019001113396 0.9568514201675351 0.7296391498266015 1.0 14.613033636809737 MALPPQEDAT(ph)ASPPR ddPTM_PC-9_AZD4547_30min_R2 4 MALPPQEDATASPPR 15 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MALPPQEDAT(0.636)AS(0.364)PPR;MALPPQEDAT(0.652)AS(0.348)PPR;MALPPQEDAT(0.585)AS(0.415)PPR;MALPPQEDAT(0.945)AS(0.055)PPR 192.54 1.2001e-07 448310000.0 1241540.9 1235821.1 1716989.6 1808834.8 1528187.4 1734132.3 1542142.6 2016770.7 1516661.1 1624807.3 True False 1636325.080545024 1635276.102776221 1694221.1960429251 1391835.883079078 1316024.9579446418 1625696.7331442023 1679390.303873927 1705125.12909525 1596828.709420997 1567923.2909798499 1.0436257245228033 1.042956700869135 1.0805510740159663 0.8876938630137137 0.8393426933037087 1.036847110121215 1.07109213412119 1.0875054531715376 1.0184354799800717 1.0 20.580423548145873 -6.976459477767484 24.99990570841546 1.0518960881021127 0.9784950880935882 0.1620547302198313 0.07202104300720638 437.6597730194046 464791.0241675836 0.028328508296362187 0.024982212996730698 1.055700001647286e-07 6.976459477767484 -0.07340100000852445 MALPPQEDAT(ph)ASPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 MALPPQEDATASPPR 15 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MALPPQEDAT(0.638)AS(0.362)PPR;MALPPQEDAT(0.616)AS(0.384)PPR;MALPPQEDAT(0.588)AS(0.412)PPR;MALPPQEDAT(0.5)AS(0.5)PPR;MALPPQEDAT(0.749)AS(0.251)PPR;MALPPQEDAT(0.5)AS(0.5)PPR 166.04 6.5349e-05 264997000.0 749723.0 852441.0 927125.0 816577.0 973411.0 682342.0 829012.0 684906.0 632345.0 586522.3 True False 876636.2961957764 937065.7088936942 949231.1761411425 770826.8380683541 782678.1022393316 646558.7843255599 750481.9818328766 666927.9432178936 641591.8493457935 692854.1500820275 1.2652537277751612 1.352471813559541 1.370030295739388 1.1125383862925484 1.1296433775372057 0.9331816577110973 1.0831745494257723 0.9625805707289702 0.9260128546099275 1.0 19.402192162876027 -6.111299456383948 1.4332769773081426 0.9866722395531965 1.3363199244877229 0.8351440880235508 0.06425596055592521 0.15192075433889765 0.6282904416337219 0.02287793847004909 0.03644337291800622 7.739279720202861e-07 6.111299456383948 0.34964768493452636 MALPPQEDAT(ph)ASPPR ddPTM_PC-9_Lapatinib_30min_R1 9 MALPPQEDATASPPR 15 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MALPPQEDAT(0.867)AS(0.133)PPR;MALPPQEDAT(0.937)AS(0.063)PPR;MALPPQEDAT(0.5)AS(0.5)PPR;MALPPQEDAT(0.766)AS(0.234)PPR;MALPPQEDAT(0.645)AS(0.355)PPR;MALPPQEDAT(0.668)AS(0.332)PPR;MALPPQEDAT(0.857)AS(0.143)PPR;MALPPQEDAT(0.539)AS(0.461)PPR;MALPPQEDAT(0.5)AS(0.5)PPR 164.7 2.154e-05 342575400.0 659109.2000000001 901746.0 922219.7 800674.7000000001 967987.8 944885.8 884634.3 845627.0 903941.1 792869.2 True False 649710.1819421758 899658.0625401104 846398.3561369888 859558.9884105022 911052.6607412371 904475.2369703801 930436.3355051264 884917.917533139 802129.7343962248 929915.5847881995 0.6986765170627351 0.9674620764045151 0.9101883762167157 0.924340878324217 0.979715444761302 0.9726423040607349 1.0005599978379172 0.9516110193321372 0.8625833866188192 1.0 19.826740232662914 -4.759235361914564 24.999907991214375 0.9514490268296452 0.6986761917640489 0.7768194035803324 0.04075300800131832 27.38869997274464 310594.0712572443 0.010318181636972727 0.06650612750044313 1.7408631728566373e-05 4.759235361914564 -0.2527728350655962 MALPPQEDAT(ph)ASPPRQK ddPTM_PC-9_AZD4547_30min_R2 1 MALPPQEDATASPPRQK 17 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MALPPQEDAT(0.5)AS(0.5)PPRQK 90.96799999999999 0.0074593 0.0 20047.0 19297.0 32073.0 63327.0 42937.0 28305.0 21293.0 30800.0 20512.0 32600.0 True False 26421.52899649633 25534.37787659776 31647.691063874085 48727.93854239685 36975.93869656903 26535.083875461325 23188.03574999325 26040.567713589706 21596.22244392205 31458.68392266774 0.8398803033669867 0.8116797873479638 1.006008107067383 1.5489503204323702 1.1753809786659828 0.8434899546557736 0.7370949085789623 0.8277704107903262 0.686494784620051 1.0 14.941170696267568 -6.855287355337056 6.013948737852448 0.7983485271608031 1.0832568734606813 0.2803118565414182 0.20561245462634284 0.300822908271125 15.856994880506155 0.08136945677891372 0.07192222752396593 1.3954447453984006e-07 6.855287355337056 0.28490834629987827 MALPPQEDAT(ph)ASPPRQK ddPTM_PC-9_Lapatinib_30min_R1 4 MALPPQEDATASPPRQK 17 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MALPPQEDAT(0.5)AS(0.5)PPRQK;MALPPQEDAT(0.5)AS(0.5)PPRQK;MALPPQEDAT(0.58)AS(0.42)PPRQK;MALPPQEDAT(0.5)AS(0.5)PPRQK 101.3 0.023812 33384200.0 188991.0 75957.0 100918.0 90587.0 70500.0 78196.0 51427.4 48625.5 97079.0 55338.7 True False 186295.9536832951 75781.12623328416 92620.91159474559 97249.07016937353 66353.32860833283 74851.73936377912 54090.05913579926 50884.818246115115 86144.94073280992 64903.92056081727 2.8703343661455585 1.1675893471223293 1.4270464833931953 1.4983543263499424 1.0223315946862934 1.153269921400825 0.8333866223861617 0.7840022267751028 1.3272686763519788 1.0 15.986018007277913 -2.974263715226464 1.3238082570953098 1.0943517651844927 199.99999996168384 0.8249280831284622 0.23712131336399286 68.35894396320604 1.3874543727304727 0.07209678919142706 40150.397211210104 0.0010610510629537084 2.974263715226464 198.90564819649936 up MALPPQEDATAS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 11 MALPPQEDATASPPR 15 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MALPPQEDAT(0.408)AS(0.592)PPR;MALPPQEDAT(0.092)AS(0.908)PPR;MALPPQEDAT(0.467)AS(0.533)PPR;MALPPQEDAT(0.352)AS(0.648)PPR;MALPPQEDAT(0.251)AS(0.749)PPR;MALPPQEDAT(0.17)AS(0.83)PPR;MALPPQEDAT(0.066)AS(0.934)PPR;MALPPQEDAT(0.005)AS(0.995)PPR;MALPPQEDAT(0.002)AS(0.998)PPR;MALPPQEDAT(0.112)AS(0.888)PPR;MALPPQEDAT(0.028)AS(0.972)PPR 201.04 3.1156e-10 288642300.0 1075440.6 1078586.4 1374791.0 1556185.0 1377583.0 1373283.0 1239710.0 1581963.0 1277691.8 1304902.0 True False 1417408.3402458925 1427218.3608933638 1356560.3730675185 1197430.5910685793 1186329.3792634695 1287411.3969173362 1350041.7883635052 1337506.968243299 1345227.9800884915 1259217.7781612582 1.1256260551813588 1.1334166223236017 1.0773040188873464 0.9509320880277738 0.942116129424235 1.0223897877277806 1.0721273252152383 1.0621728754468196 1.0683044691862813 1.0 20.2640963839957 -5.533654074045923 7.280376184503495 1.0183763801381536 1.1239488113606788 0.5342691252865255 0.0425659934062235 0.11928831675616156 35.95264089308199 0.013398191379166695 0.024281085016602942 2.926482463092675e-06 5.533654074045923 0.10557243122252524 MALPPQEDATAS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 MALPPQEDATASPPR 15 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MALPPQEDAT(0.398)AS(0.602)PPR;MALPPQEDAT(0.181)AS(0.819)PPR;MALPPQEDAT(0.257)AS(0.743)PPR;MALPPQEDAT(0.332)AS(0.668)PPR;MALPPQEDAT(0.002)AS(0.998)PPR 163.62 7.3449e-05 472002000.0 1289835.0 1600691.0 1657374.0 1517340.0 1683249.0 1234021.0 1539136.0 1269257.0 1226471.0 1080336.0 True False 1508178.5900975189 1759597.0238817197 1696892.081785899 1432328.359082653 1353428.4417540468 1169306.766390186 1393337.8957003388 1235940.3486389534 1244405.818119826 1276192.3648649321 1.1817799820931694 1.3787866722333426 1.3296522753961877 1.1223451875409438 1.060520716951076 0.9162464833535824 1.0917930039863581 0.9684592876950499 0.9750926681429642 1.0 20.283414377204046 -6.01046142136378 2.2726097851371274 0.9983545048749474 1.3059312644567853 0.8000540472074881 0.065700280212257 0.12292773909484185 1.271709092014501 0.020277746003768957 0.031107118271860905 9.761994949584933e-07 6.01046142136378 0.30757675958183794 MALPPQEDATAS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 8 MALPPQEDATASPPR 15 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MALPPQEDAT(0.175)AS(0.825)PPR;MALPPQEDAT(0.085)AS(0.915)PPR;MALPPQEDAT(0.403)AS(0.597)PPR;MALPPQEDAT(0.326)AS(0.674)PPR;MALPPQEDAT(0.139)AS(0.861)PPR;MALPPQEDAT(0.002)AS(0.998)PPR;MALPPQEDAT(0.013)AS(0.987)PPR;MALPPQEDAT(0.003)AS(0.997)PPR 220.72 3.0659e-18 396347000.0 862384.5 1261527.0 1306430.0 1123359.5 1337479.0 1254406.0 1158159.0 1190313.0 1266321.0 1050670.0 True False 850086.73888805 1258606.0117394896 1199020.368365635 1205975.1050474355 1258811.114804887 1200757.9795432086 1218122.806104492 1245619.2874312447 1123694.5940287043 1232276.909570225 0.6898504161572989 1.0213662221249016 0.9730121201279436 0.9786559300766556 1.0215326644754839 0.9744222018750566 0.9885138613279141 1.0108274185431854 0.9118848087647845 1.0 20.232895055206214 -4.757417946241809 24.999951836609327 0.9871128186802989 0.6898499856081108 0.8962579124980218 0.030297058420363687 32.41867469462085 201508.9865667349 0.00708700707333964 0.052727400313810055 1.7481635218226913e-05 4.757417946241809 -0.29726283307218804 MALPPQEDATAS(ph)PPRQK ddPTM_PC-9_AZD4547_30min_R2 9 MALPPQEDATASPPRQK 17 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MALPPQEDAT(0.017)AS(0.983)PPRQK;MALPPQEDAT(0.115)AS(0.885)PPRQK;MALPPQEDAT(0.026)AS(0.974)PPRQK;MALPPQEDAT(0.233)AS(0.767)PPRQK;MALPPQEDAT(0.016)AS(0.984)PPRQK;MALPPQEDAT(0.008)AS(0.992)PPRQK;MALPPQEDAT(0.152)AS(0.848)PPRQK;MALPPQEDATAS(1)PPRQK;MALPPQEDAT(0.017)AS(0.983)PPRQK 175.7 1.1495e-05 317681700.0 541496.0 293408.50000000006 666977.0 1406726.0 1101787.0 674303.0 463708.0 645494.0 473481.0 768541.0 True False 713680.464183509 388247.0597090604 658132.4491849696 1082427.054400046 948822.8932779813 632138.7268141747 504977.1136785746 545747.73427649 498508.2390293807 741634.6135156729 0.9623073831470069 0.5235018061907862 0.8874079461652061 1.459515285119808 1.279367057559713 0.8523587158608472 0.680897445286112 0.7358714444157437 0.6721749901426975 1.0 19.500349053327533 -6.99130252812226 24.9777784801012 0.7525684884816339 1.016922486863169 0.18947367289564265 0.24517082388799852 357.2787981312098 1026043.5988214947 0.09744602887241664 0.0858121211990088 1.020228548233387e-07 6.99130252812226 0.26435399838153506 MALPPQEDATAS(ph)PPRQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 MALPPQEDATASPPRQK 17 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MALPPQEDAT(0.077)AS(0.923)PPRQK;MALPPQEDAT(0.001)AS(0.999)PPRQK;MALPPQEDAT(0.044)AS(0.956)PPRQK;MALPPQEDAT(0.104)AS(0.896)PPRQK;MALPPQEDAT(0.004)AS(0.996)PPRQK;MALPPQEDAT(0.082)AS(0.918)PPRQK 170.79 2.8298000000000002e-05 199958200.0 353867.0 116291.6 263899.0 519220.0 491016.0 661663.0 467881.0 659764.0 600485.0 398027.0 True False 413769.6939081647 127836.26150359002 270191.3530025305 490129.78673395247 394804.939587849 626964.2274888589 423559.92451490235 642445.8940777405 609265.9571189905 470186.1443200009 0.8800125203743986 0.2718843654750209 0.5746476289582935 1.042416482609871 0.8396779538427898 1.333438330888282 0.9008345516592562 1.3663650063675685 1.2957973442627313 1.0 18.842872499996545 -6.005942800284456 1.3853892739901068 1.1704590972302487 0.5312129489697143 0.5497373884440058 0.21961973341501945 0.29749302496072083 1.1574428944192685 0.07654986765125123 0.13746186268152757 9.86409394307614e-07 6.005942800284456 -0.6392461482605344 MALPPQEDATAS(ph)PPRQK ddPTM_PC-9_Lapatinib_30min_R1 8 MALPPQEDATASPPRQK 17 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MALPPQEDAT(0.049)AS(0.951)PPRQK;MALPPQEDAT(0.003)AS(0.997)PPRQK;MALPPQEDAT(0.019)AS(0.981)PPRQK;MALPPQEDAT(0.023)AS(0.977)PPRQK;MALPPQEDAT(0.008)AS(0.992)PPRQK;MALPPQEDAT(0.077)AS(0.923)PPRQK;MALPPQEDAT(0.01)AS(0.99)PPRQK;MALPPQEDAT(0.021)AS(0.979)PPRQK 106.19 0.00089995 226810000.0 2009571.0 706373.0 1111393.0 828137.0 709254.0 815163.0 553128.0 483442.0 952667.0 540161.0 True False 1980914.149029816 704737.4367179285 1020018.5576410427 889040.9575640493 667537.0741670154 780300.3787277641 581766.2613639104 505904.4802117889 845367.6104317496 633527.1091307094 3.126802500603196 1.1124029683353722 1.6100629995781164 1.4033195182191047 1.0536835196886405 1.231676383664858 0.9182973435220122 0.7985522212395344 1.3343826937283172 1.0 19.273046829196183 -3.2033034749217415 1.5125268422303464 1.1359817305768187 199.9999739979375 0.8414501149583765 0.25177555995214757 54.08404902236962 1.5950126020886806 0.07271434765269605 36168.86111386066 0.0006261761543705015 3.2033034749217415 198.8639922673607 up MANS(ph)SPVLSK ddPTM_PC-9_AZD4547_30min_R2 1 MANSSPVLSK 10 0 Q9NXE8 Q9NXE8 CWC25 Pre-mRNA-splicing factor CWC25 homolog 1 MANS(0.997)S(0.003)PVLSK 110.93 0.0014690999999999999 48252000.0 173360.0 167690.0 233010.0 305340.0 254040.0 233790.0 184290.0 246910.0 197690.0 209610.0 True False 228484.87388799377 221892.51314332194 229920.13515397054 234948.58045597398 218770.93104959326 219171.07434178106 200691.4529829646 208755.73292735202 208139.48980786608 202271.61770031846 1.1295943369895443 1.0970027118291672 1.1366900495877557 1.1615499155401479 1.0815700864849949 1.083548333837427 0.9921879068585144 1.0320564758454658 1.0290098639357368 1.0 17.625934372802305 -6.901690097247869 1.804025379920105 1.0159304542783398 1.1272633128194958 0.8320700356549036 0.022931885306988257 0.1395095383021662 0.928840038409534 0.010182062436805793 0.008382356278580607 1.2540357073558382e-07 6.901690097247869 0.11133285854115593 MANS(ph)SPVLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MANSSPVLSK 10 0 Q9NXE8 Q9NXE8 CWC25 Pre-mRNA-splicing factor CWC25 homolog 1 MANS(0.64)S(0.359)PVLS(0.001)K;MANS(0.974)S(0.026)PVLSK 79.283 0.016941 32843000.0 267710.0 253780.0 298160.0 319130.0 357160.0 277300.0 302910.0 295740.0 258530.0 259830.0 True False 313028.01548648137 278973.60122640873 305269.26517809666 301250.1807334197 287177.0618945129 262757.899841249 274216.1719215122 287977.1383624315 262310.5121592917 306935.1221868512 1.0198507530067575 0.9089008753341024 0.9945726087099916 0.9814783612480467 0.9356278937660634 0.8560698364173889 0.8934010873952025 0.9382345569013155 0.8546122395194851 1.0 18.227574215404452 -6.506591032568451 6.043571767223173 0.9027202462738293 0.9713591407645277 0.30899320465542823 0.047127255968587016 0.19392930071120998 26.975608194920344 0.014348099902390936 0.01545759907862646 3.1146479654534177e-07 6.506591032568451 0.06863889449069838 MANS(ph)SPVLSK ddPTM_PC-9_Lapatinib_30min_R1 2 MANSSPVLSK 10 0 Q9NXE8 Q9NXE8 CWC25 Pre-mRNA-splicing factor CWC25 homolog 1 MANS(0.5)S(0.5)PVLSK;MANS(0.69)S(0.309)PVLS(0.001)K 145.14 0.00013651 54996700.0 129801.0 120391.0 144979.0 119839.0 119417.0 114788.0 112982.0 105673.0 124194.0 94324.0 True False 127950.01393741176 120112.24203630094 133059.38625512389 128652.35983118453 112393.1268428551 109878.78482389728 118831.6551348283 110582.95335825282 110205.96389920158 110627.7777211704 1.156581254482946 1.0857331179429048 1.2027665112327466 1.1629299845057346 1.0159575574783228 0.9932296127364965 1.0741574818065605 0.9995948181926736 0.9961870894393995 1.0 16.755354154303603 -6.264751540907893 24.764004826165987 1.0152180737072756 1.1508951633006033 0.7951100138060948 0.03451035437853855 116.83408723645009 873530.9002831597 0.010770288461167564 0.012721773390775069 5.435612129490372e-07 6.264751540907893 0.1356770895933277 MANSS(ph)PVLSK ddPTM_PC-9_AZD4547_30min_R2 4 MANSSPVLSK 10 0 Q9NXE8 Q9NXE8 CWC25 Pre-mRNA-splicing factor CWC25 homolog 1 MANS(0.008)S(0.992)PVLSK;MANS(0.071)S(0.926)PVLS(0.003)K;MANS(0.082)S(0.918)PVLSK;MANS(0.225)S(0.772)PVLS(0.003)K 124.39 0.00036499 77349400.0 363170.0 299908.0 393191.0 531699.0 472995.0 405384.0 363020.0 443188.0 368313.0 398015.0 True False 478650.50559473154 396847.3959794104 387977.0304335643 409124.0102176616 407327.80873800395 380035.2743956909 395328.076737075 374703.4780470903 387781.2732541076 384080.61599633796 1.2462240625007102 1.0332398445830293 1.0101447828266956 1.0652034837956061 1.060526857574837 0.9894674674217726 1.0292841145121583 0.9755854954436517 1.0096351055055717 1.0 18.55104962937159 -4.761300779995005 5.069707138270279 1.0193766129766495 1.26025578871658 0.8651163734183835 0.02694441692380359 0.06144712998093966 4.263124294883943 0.007166682990853708 0.05278159230818446 1.7326036301800778e-05 4.761300779995005 0.24087917573993045 MANSS(ph)PVLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MANSSPVLSK 10 0 Q9NXE8 Q9NXE8 CWC25 Pre-mRNA-splicing factor CWC25 homolog 1 MANS(0.28)S(0.712)PVLS(0.008)K;MANS(0.065)S(0.894)PVLS(0.042)K 114.87 0.0010318 87295000.0 268420.0 285970.0 313490.0 347000.0 342410.0 295240.0 328260.0 315890.0 289280.0 226616.0 True False 313858.2044633435 314359.2116901097 320964.79051744624 327558.7149891783 275317.21851075115 279757.0946596842 297164.83640340547 307598.2222131211 293510.1727360071 267699.68690873124 1.1724264906232387 1.1742980177533282 1.1989733504129014 1.2236051478866885 1.028455511808712 1.0450407988525732 1.1100679266192792 1.1490421440724088 1.0964158237363781 1.0 18.030255926095798 -6.255481051597375 24.999973945892968 1.0795608736839664 1.1915128874044498 0.6590509572589109 0.04233433835134823 353.4992848537939 1483212.7237018584 0.013474447050046993 0.01695793259949483 5.552888440151284e-07 6.255481051597375 0.11195201372048347 MAPALS(ph)GANLTSPR ddPTM_PC-9_AZD4547_30min_R2 1 MAPALSGANLTSPR 14 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MAPALS(0.428)GANLT(0.144)S(0.428)PR 64.53399999999999 0.041017000000000005 11925000.0 28046.0 21857.0 38791.0 49210.0 40971.0 38739.0 31726.0 38958.0 34784.0 33320.0 True False 36964.04460696047 28921.847813069257 38276.60599441085 37865.39478692105 35282.883860938804 36316.644206023535 34549.552538594166 32937.936265780125 36622.61122705656 32153.476941818684 1.1496126740459967 0.8994936337803523 1.190434429958287 1.1776454178015652 1.0973271700843659 1.129477980615846 1.0745199531954555 1.024397340461217 1.1389938106328195 1.0 14.972687132514675 -9.767841942009303 8.390514876527297 0.9999967678485088 1.095264798753873 0.11550487804217624 0.08103297638832373 0.0 0.0 0.07815464035173197 0.01895528454719713 1.7067034169964529e-10 9.767841942009303 0.09526803090536429 MAPALSGANLT(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 MAPALSGANLTSPR 14 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MAPALS(0.016)GANLT(0.645)S(0.338)PR 81.789 0.038225999999999996 3936300.0 15162.0 14635.0 18244.0 27707.0 22790.0 20790.0 18774.0 22232.0 19057.0 20085.0 True False 19983.20061080849 19365.47754697664 18002.072639582173 21319.579218882773 19626.001884034948 19489.998013454893 20444.84962994285 18796.55524053659 20064.314114363424 19381.830263398202 1.031027531416677 0.9991562862640251 0.9288117992436635 1.0999776042381266 1.0125979650692667 1.0055808841882679 1.054846180783665 0.9698029022590874 1.035212559479177 1.0 14.242417193194594 -5.743695437403952 24.999994712254434 1.0240367896192222 0.9876143733989374 0.16369023294717366 0.040382358206304175 485.10382115438426 683472.5645892645 0.010789100173143806 0.018636985740319488 1.8042826069347822e-06 5.743695437403952 -0.03642241622028475 MAPALSGANLT(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 2 MAPALSGANLTSPR 14 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MAPALS(0.064)GANLT(0.625)S(0.311)PR;MAPALSGANLT(0.8)S(0.2)PR 129.77 5.2665e-05 24640000.0 65259.0 62638.0 70429.0 56997.0 68024.0 67698.0 56760.0 51170.0 67102.0 49171.0 True False 64328.39469296512 62492.96555946727 64638.599483802005 61188.7495164182 64022.962060329686 64802.714351745846 59698.75507118704 53547.54500526909 59544.26614461436 57670.14183376095 1.1154540746301118 1.0836277417109277 1.1208330243079379 1.0610126413907552 1.110157874154034 1.1236787753799036 1.0351761444123675 0.9285141895371856 1.0324973071204806 1.0 15.81553695010838 -7.485378010038419 4.8526244159481156 0.9841307303619583 1.1000836037249981 0.7539096745321576 0.029828523905152785 0.0890767581490607 5.094412211424839 0.012648357366059036 0.007970757493715716 3.27055901406674e-08 7.485378010038419 0.11595287336303983 MAPALSGANLTS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 MAPALSGANLTSPR 14 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MAPALS(0.001)GANLT(0.085)S(0.914)PR;MAPALS(0.001)GANLT(0.349)S(0.649)PR 123.68 4.0479e-05 43841700.0 52489.0 49746.0 67242.0 91259.0 77106.0 66444.0 62488.0 87053.0 63793.0 67977.0 True False 69179.41016097655 65825.42166394932 66350.32714485767 70220.64748749508 66401.16284644122 62289.24617633469 68049.3109447038 73600.95912893272 67164.9677440093 65597.14592058834 1.0546100625280996 1.003479964564881 1.011481920649126 1.0704832733500926 1.0122568888412649 0.949572505055964 1.0373821907904963 1.1220146562174178 1.0239007627758523 1.0 16.001345425249696 -7.523848699463318 24.999829516353756 1.0597143079435563 1.0162629397515013 0.0881881930856998 0.042178209431593276 59.670548277808386 1537825.6794722646 0.01950602557877383 0.011379673595338782 2.993307270432084e-08 7.523848699463318 -0.04345136819205497 MAPALSGANLTS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 MAPALSGANLTSPR 14 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MAPALS(0.001)GANLT(0.24)S(0.758)PR;MAPALS(0.011)GANLT(0.225)S(0.764)PR;MAPALS(0.034)GANLT(0.367)S(0.599)PR;MAPALS(0.055)GANLT(0.077)S(0.868)PR;MAPALSGANLT(0.095)S(0.904)PR 99.238 0.0019859 330475800.0 442548.0 457724.0 471967.0 519401.0 574764.0 479591.0 513810.0 454894.0 438273.0 361007.0 True False 517462.6356785776 503163.81372746767 483220.48322481505 490300.6458907617 462143.1201778979 454440.4036882964 465138.19713773817 442953.5145000331 444681.9134939444 426454.71137016 1.2134058362634041 1.1798763158480494 1.133110903317897 1.149713282133689 1.083686280995875 1.0656240664529673 1.090709481537422 1.0386882890257303 1.0427412375518659 1.0 18.70203301281292 -1.5228787452803376 0.17719265831705278 0.9848595244535735 1.982078965642215 0.9443626340395676 0.01517326528030894 11.860583009050966 0.13219390552338103 0.03558654651018433 3.1701255286761745 0.029999999999999995 1.5228787452803376 0.9972194411886416 MAPALSGANLTS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 MAPALSGANLTSPR 14 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MAPALSGANLT(0.005)S(0.995)PR;MAPALS(0.001)GANLT(0.113)S(0.887)PR;MAPALS(0.001)GANLT(0.098)S(0.901)PR;MAPALSGANLT(0.034)S(0.966)PR 159.41 7.5743e-05 244814300.0 419073.0 405782.0 455782.0 394227.0 400618.0 389168.0 348078.0 371661.0 422772.0 322133.0 True False 413096.942171425 404842.43671017204 418309.36332939897 423219.76868272014 377054.43688529206 372524.1918349171 366099.7756812659 388929.7268751873 375154.96537347423 377813.25983475824 1.0933892112524015 1.0715411017793166 1.107185500880388 1.1201824119879251 0.9979915396569246 0.9860008407270979 0.9689966303495664 1.0294231786499262 0.9929639990336849 1.0 18.5273138102609 -6.2706160714459065 24.664929767566214 0.995527453957924 1.096830091476239 0.8842173898595831 0.018111174826490994 180.07309119926217 483995.6854130829 0.0058935419201551955 0.006776323994924614 5.362705262753322e-07 6.2706160714459065 0.10130263751831503 MAPPVDDLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 6 MAPPVDDLSPK 11 0 Q92576-2;Q92576;E7ER40;E7EVH3 Q92576-2 PHF3 PHD finger protein 3 1 MAPPVDDLS(1)PK;MAPPVDDLS(1)PK;MAPPVDDLS(1)PK;MAPPVDDLS(1)PK;MAPPVDDLS(1)PK;MAPPVDDLS(1)PK 145.81 0.00018787 167672700.0 842593.0 710551.0 617768.0 723099.0 722348.0 663085.0 770666.0 625127.0 640409.0 677402.0 True False 1110520.0469768452 940222.7151678711 609575.99267756 556399.6973181836 622062.4488340871 621622.1901275491 839253.781022133 528527.9861393898 674259.7123191141 653686.3621651232 1.6988576039717413 1.4383391938202434 0.9325205908511507 0.8511722586276556 0.9516221919847124 0.9509486905442359 1.2838783698077747 0.8085345155263954 1.031472815320559 1.0 19.31823907303142 -5.0998912389847275 3.0788927441576694 0.9736128823781368 1.6719771101855614 0.7963002647994784 0.12281537135403785 0.11081008072483713 1.9277061156015045 0.032934357153341094 0.12624473425488303 7.945271844402082e-06 5.0998912389847275 0.6983642278074246 MAPPVDDLS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MAPPVDDLSPK 11 0 Q92576-2;Q92576;E7ER40;E7EVH3 Q92576-2 PHF3 PHD finger protein 3 1 MAPPVDDLS(1)PK 84.169 0.034953 0.0 30731.0 41824.0 29400.0 37084.0 38074.0 32914.0 30173.0 32713.0 25305.0 28868.0 True False 35933.15133508305 45976.01031481336 30101.00750012089 35006.30370795016 30613.673016495883 31187.931898214505 27314.795006397275 31854.318412288565 25675.03775264336 34101.53988103775 1.053710520417401 1.3482092150442284 0.8826876324391038 1.0265314654431632 0.8977211329251056 0.9145608088963934 0.800984210733127 0.9341020529692045 0.7528996591417864 1.0 15.05754926626451 -5.277616352965923 24.79749203956056 0.9000842898347547 1.2009598633864387 0.5838054917101291 0.10124028119568851 406.4022866780023 622969.0935163444 0.025165330912208354 0.05265105461608611 5.2769581148220285e-06 5.277616352965923 0.30087557355168393 MAPPVDDLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 9 MAPPVDDLSPK 11 0 Q92576-2;Q92576;E7ER40;E7EVH3 Q92576-2 PHF3 PHD finger protein 3 1 MAPPVDDLS(1)PK;MAPPVDDLS(1)PK;MAPPVDDLS(1)PK;MAPPVDDLS(1)PK;MAPPVDDLS(1)PK;MAPPVDDLS(1)PK;MAPPVDDLS(1)PK;MAPPVDDLS(1)PK;MAPPVDDLS(1)PK 151.66 0.00035894 229418800.0 1483491.0 1317814.0 904095.0 1131044.0 1086325.0 1010462.0 1119339.0 1041535.0 890880.0 981162.0 True False 1462336.1463010672 1314762.68264925 829763.7990076222 1214224.7488121793 1022429.4992971248 967246.895761968 1177292.8964522104 1089928.5184104564 790539.7130177057 1150754.5443838157 1.2707628689696735 1.1425222599083926 0.7210606319629426 1.0551552933143962 0.8884861713447293 0.8405327621624914 1.0230616965172228 0.947142484667806 0.6869750954935476 1.0 20.13414870916779 -5.063502146129629 5.708816937586399 0.9018967370948621 1.2431873253773893 0.5475829734811313 0.11565277123059439 0.13286694588283057 8.620721073701356 0.028355000791360607 0.08135057054687787 8.639683912478187e-06 5.063502146129629 0.34129058828252723 MAPTPIPT(ph)RSPSDSSTASTPVAEQIER ddPTM_PC-9_AZD4547_30min_R2 5 MAPTPIPTRSPSDSSTASTPVAEQIER 27 1 Q16643-3;Q16643;Q16643-2;D6R9Q9 Q16643-3 DBN1 Drebrin 1 MAPT(0.001)PIPT(0.477)RS(0.477)PS(0.035)DS(0.003)S(0.001)TAS(0.003)T(0.003)PVAEQIER;MAPT(0.006)PIPT(0.758)RS(0.222)PS(0.006)DS(0.005)S(0.002)T(0.001)ASTPVAEQIER;MAPT(0.001)PIPT(0.498)RS(0.498)PS(0.001)DSSTASTPVAEQIER;MAPT(0.003)PIPT(0.331)RS(0.331)PS(0.331)DS(0.001)S(0.001)T(0.001)AS(0.001)T(0.001)PVAEQIER;MAPT(0.001)PIPT(0.499)RS(0.499)PS(0.002)DSSTASTPVAEQIER 92.88600000000001 6.5947e-08 1330372000.0 166529.9 148969.4 258689.0 357725.0 307570.0 235589.1 199397.8 259526.0 196498.8 247770.0 True False 219482.94416289852 197120.84529460748 255258.61483561018 275257.0280461562 264869.2145446523 220857.6763343738 217143.8179152773 219422.22001419068 206885.32540774895 239095.6477153186 0.917971306714156 0.8244434692902114 1.067600423825097 1.151242319449886 1.1077960518127927 0.9237210231335536 0.908188082845496 0.917717332418563 0.8652826907751949 1.0 17.867228343187 -6.955462870725768 23.9129344762585 0.9159421248131486 1.0140984142239369 0.19318123838836077 0.0923877498210074 155.0763057704034 83262.81894086169 0.03689821828139153 0.0325411454241174 1.1079932873425002e-07 6.955462870725768 0.09815628941078824 MAPTPIPT(ph)RSPSDSSTASTPVAEQIER ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 MAPTPIPTRSPSDSSTASTPVAEQIER 27 1 Q16643-3;Q16643;Q16643-2;D6R9Q9 Q16643-3 DBN1 Drebrin 1 MAPTPIPT(0.488)RS(0.488)PS(0.023)DSSTASTPVAEQIER;MAPT(0.003)PIPT(0.498)RS(0.498)PSDSSTASTPVAEQIER;MAPT(0.002)PIPT(0.523)RS(0.365)PS(0.106)DS(0.002)S(0.001)T(0.001)ASTPVAEQIER;MAPT(0.021)PIPT(0.888)RS(0.077)PS(0.008)DS(0.001)S(0.001)T(0.001)AS(0.001)T(0.002)PVAEQIER;MAPT(0.036)PIPT(0.459)RS(0.459)PS(0.03)DS(0.005)S(0.002)T(0.001)AS(0.002)T(0.006)PVAEQIER 92.51799999999999 9.0163e-08 549053700.0 206383.5 208804.4 263496.0 274477.0 335840.0 301047.0 256775.8 270847.9 235629.0 174975.4 True False 241320.1502900693 229533.1208917947 269778.74395414506 259098.94355643998 270034.5628476123 285259.56535704504 232452.13732819655 263738.429612072 239074.62835872706 206697.05491549522 1.1675064765133163 1.1104808483393034 1.305189104239728 1.2535202480865943 1.3064267556110638 1.3800852918473794 1.124603044892105 1.275966073729968 1.1566426452300875 1.0 17.65715830737492 -8.605516245439885 3.1491633994222057 1.0000546880177785 1.2415486550680428 0.4532351534926652 0.0808134656685837 0.3375488940968371 8.119532733056577 0.08107909982208435 0.021516152218563546 2.4801831609672132e-09 8.605516245439885 0.24149396705026427 MAPTPIPT(ph)RSPSDSSTASTPVAEQIER ddPTM_PC-9_Lapatinib_30min_R1 5 MAPTPIPTRSPSDSSTASTPVAEQIER 27 1 Q16643-3;Q16643;Q16643-2;D6R9Q9 Q16643-3 DBN1 Drebrin 1 MAPT(0.113)PIPT(0.438)RS(0.438)PS(0.007)DS(0.001)S(0.001)TASTPVAEQIER;MAPT(0.013)PIPT(0.467)RS(0.467)PS(0.036)DS(0.006)S(0.002)T(0.002)AS(0.003)T(0.003)PVAEQIER;MAPT(0.013)PIPT(0.491)RS(0.491)PS(0.004)DSSTASTPVAEQIER;MAPT(0.003)PIPT(0.498)RS(0.498)PSDSSTASTPVAEQIER;MAPT(0.001)PIPT(0.927)RS(0.062)PS(0.009)DS(0.002)STASTPVAEQIER 110.91 1.5659e-10 571993000.0 285959.0 227327.0 254908.0 212688.0 246604.0 241321.0 190034.0 197044.0 246887.0 155827.0 True False 281881.1722215413 226800.6382984298 233950.4482133354 228329.78502636895 232099.237562118 231000.263376727 199873.03067649665 206199.3835844881 219079.98622463437 182761.48932357423 1.542344469093696 1.2409651460920492 1.2800861334585236 1.2493320440288014 1.2699570266205953 1.263943866028293 1.093627718926206 1.1282430688634721 1.1987207317880806 1.0 17.479602578667162 -1.5228787452803383 0.14869785226506907 0.985719143253544 2.5807449633130233 0.7170817211102541 0.07254805067570101 39.8362299767975 0.3905570248057495 0.26519635404530084 13.673285978235397 0.02999999999999995 1.5228787452803383 1.5950258200594791 MAPTPIPTRS(ph)PSDSSTASTPVAEQIER ddPTM_PC-9_AZD4547_30min_R2 4 MAPTPIPTRSPSDSSTASTPVAEQIER 27 1 Q16643-3;Q16643;Q16643-2;D6R9Q9 Q16643-3 DBN1 Drebrin 1 MAPT(0.062)PIPT(0.195)RS(0.651)PS(0.078)DS(0.005)S(0.002)T(0.001)AS(0.003)T(0.003)PVAEQIER;MAPTPIPT(0.388)RS(0.61)PS(0.001)DSSTASTPVAEQIER;MAPTPIPT(0.012)RS(0.77)PS(0.154)DS(0.041)S(0.015)T(0.006)AS(0.001)T(0.001)PVAEQIER;MAPTPIPT(0.136)RS(0.756)PS(0.092)DS(0.009)S(0.003)T(0.004)AST(0.001)PVAEQIER 125.08 1.0942000000000001e-11 126984000.0 96793.0 93701.0 132364.0 180510.0 183109.0 153926.0 111569.0 161980.0 104158.0 137936.0 True False 127571.16058052947 123988.0158270759 130608.7668748987 138896.20835169934 157687.47604141058 144300.98288691966 121498.42486220833 136949.71293010563 109663.57923722862 133106.90262445057 0.9584113074921463 0.9314920066684835 0.9812321096780373 1.0434936551982041 1.184667909269228 1.084098420455716 0.9127883112493832 1.0288701053806144 0.8238759754378387 1.0 17.022225862544992 MAPTPIPTRS(ph)PSDSSTASTPVAEQIER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 MAPTPIPTRSPSDSSTASTPVAEQIER 27 1 Q16643-3;Q16643;Q16643-2;D6R9Q9 Q16643-3 DBN1 Drebrin 1 MAPTPIPT(0.164)RS(0.824)PS(0.011)DSSTASTPVAEQIER;MAPTPIPT(0.047)RS(0.931)PS(0.022)DSSTASTPVAEQIER;MAPTPIPT(0.135)RS(0.719)PS(0.135)DS(0.003)S(0.004)T(0.002)AS(0.001)T(0.001)PVAEQIER;MAPTPIPT(0.192)RS(0.802)PS(0.005)DS(0.001)STASTPVAEQIER 134.8 2.0793e-10 283142000.0 81031.8 62331.0 85447.0 103859.1 107451.7 106806.9 89421.6 99760.8 97035.1 77566.4 True False 94748.88328899763 68518.80974877185 87484.38053955194 98040.21134274511 86397.31073348265 101205.75814119837 80950.93869167985 97142.18470530497 98454.05476512636 91628.57430471564 1.0340538855696395 0.7477886703869139 0.9547718187627589 1.0699742093193247 0.9429079453551668 1.104521803478392 0.8834682772916803 1.0601734823708326 1.0744907416949676 1.0 16.483509951443757 -5.519685564112241 24.77702725605008 1.016247201944419 0.8810110167614442 0.24826652870248145 0.08969057857942692 129.59706217245324 1005587.9550074202 0.022599654349282638 0.040184103024830366 3.02213900363598e-06 5.519685564112241 -0.13523618518297487 MAPTPIPTRS(ph)PSDSSTASTPVAEQIER ddPTM_PC-9_Lapatinib_30min_R1 6 MAPTPIPTRSPSDSSTASTPVAEQIER 27 1 Q16643-3;Q16643;Q16643-2;D6R9Q9 Q16643-3 DBN1 Drebrin 1 MAPTPIPT(0.073)RS(0.914)PS(0.012)DSSTASTPVAEQIER;MAPT(0.007)PIPT(0.157)RS(0.803)PS(0.032)DS(0.001)STASTPVAEQIER;MAPT(0.004)PIPT(0.188)RS(0.806)PS(0.001)DSSTASTPVAEQIER;MAPT(0.004)PIPT(0.182)RS(0.783)PS(0.012)DS(0.004)S(0.004)T(0.005)AS(0.001)T(0.005)PVAEQIER;MAPT(0.001)PIPT(0.147)RS(0.702)PS(0.147)DS(0.002)S(0.001)T(0.001)ASTPVAEQIER;MAPTPIPT(0.033)RS(0.964)PS(0.004)DSSTASTPVAEQIER 123.29 6.1922e-13 610320000.0 314608.0 258984.0 322673.0 277195.0 294645.0 271443.0 226222.0 235766.0 292719.0 194308.0 True False 310121.6322279593 258384.3384599291 296144.07149379957 297580.84499541204 277314.56039435795 259834.0156545383 237934.66824725282 246720.54906609855 259749.90375227822 227893.8789008649 1.3608159803311959 1.1337923585579397 1.299482342053706 1.3057869146404821 1.2168583102444421 1.1401535526435422 1.0440590567628003 1.0826115657692736 1.1397844690039738 1.0 17.79800264959745 -6.810394259713524 2.3074790943566144 1.0741517716501292 1.266108968325128 0.6838001389410382 0.06393327260536877 0.18203118234326296 1.9866845662839163 0.024533708448464423 0.021954706050682272 1.547411215590465e-07 6.810394259713524 0.1919571966749989 MAPYQGPDAVPGALDYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MAPYQGPDAVPGALDYK 17 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 139.86 9.634299999999999e-08 0.0 8110.0 8502.3 7861.8 10633.0 10968.0 8126.9 9292.7 8227.6 9313.1 9307.2 False True 9482.862820198607 9346.352154256832 8049.255128042533 10037.267482651121 8818.89913444679 7700.711057410203 8412.428182678152 8011.634217862786 9449.2864688458 10994.521684245343 0.8625079919381236 0.8500917477519496 0.73211508051112 0.9129335291624442 0.8021175807114809 0.7004134675949547 0.7651472637261505 0.7286932936194122 0.8594540754225083 1.0 13.424497220779385 -5.03044648579882 24.051050645546614 0.799804487929221 0.8594040238976353 0.022916972767732635 0.08784522598219198 1052.6703231620638 831555.606892471 0.021516494466421374 0.057122181165285814 9.322953416302475e-06 5.03044648579882 0.059599535968414274 MAPYQGPDAVPGALDYK ddPTM_PC-9_Lapatinib_30min_R1 4 MAPYQGPDAVPGALDYK 17 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ;;; 190.86 4.2769000000000004e-08 24174400.0 135787.0 106240.0 128234.0 120663.0 126956.0 115816.0 125529.0 101622.0 120016.0 121496.0 False True 133850.65247971402 105994.00780736614 117691.09551755458 129536.95953996792 119488.69768509945 110862.81966028239 132028.27740188572 106343.72910935013 106498.53425549217 142496.42171675616 0.9393264116187594 0.74383627694212 0.8259231642426238 0.9090541220568464 0.838538233069531 0.7780042356477365 0.9265374934419178 0.7462905231454325 0.7473769023279901 1.0 17.12056616609098 -6.526132137268388 24.458290597311038 0.826888784912789 0.8482357353177788 0.0 0.08859952682823156 537.5216355039519 4040893.621264332 0.028444536188196888 0.028606653884848714 2.9776103318995876e-07 6.526132137268388 0.021346950404989795 MARS(ph)RSRSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MARSRSRSPR 10 3 A2AJT9-3;A2AJT9-2;A2AJT9 A2AJT9-3 CXorf23 Uncharacterized protein CXorf23 1 MARS(0.835)RS(0.128)RS(0.038)PR 66.663 0.024905 3678500.0 19309.0 31106.0 33817.0 30716.0 71323.0 72161.0 31569.0 53257.0 70953.0 67157.0 True False 22577.632329866214 34193.9981076077 34623.32553168666 28995.082102615608 57347.77014643949 68376.75012781969 28578.555780232517 51859.06018045586 71990.55339511171 79332.03248548043 0.2845966707584157 0.431023850471321 0.4364356294290521 0.36549022121577895 0.7228829055518707 0.8619059412140259 0.36023980332866223 0.6536963513439196 0.9074588301804523 1.0 16.275615890835432 -6.5610925431824505 0.17534083045086019 1.1243312626315565 1.9677495189558556e-17 0.6201373293865499 0.15201228666498615 6.169375923351844 0.4447093938277275 0.7372487091784191 1.9086344970052294 2.747308670697264e-07 6.5610925431824505 -1.1243312626315565 MAS(ph)NIFGTPEENQASWAK ddPTM_PC-9_AZD4547_30min_R2 3 MASNIFGTPEENQASWAK 18 0 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 MAS(0.966)NIFGT(0.034)PEENQASWAK;MAS(0.995)NIFGT(0.005)PEENQASWAK;MAS(0.966)NIFGT(0.034)PEENQASWAK 150.51 2.915e-08 42782400.0 85044.0 83853.0 106188.0 146043.0 138480.0 118363.0 93460.0 131851.0 106021.0 114568.0 True False 112086.22297491092 110956.8424152122 104779.87773799343 112375.0426918576 119254.44233879594 110961.74289882451 101777.75894398957 111476.45758456209 111625.05361383868 110557.00919178536 1.013831902602148 1.003616534368556 0.9477452266841786 1.0164443079037935 1.0786692151912591 1.0036608597681678 0.9205907403612352 1.0083165092787716 1.0096605762932729 1.0 16.75443096775625 -7.01758370945227 24.913669821761204 0.9820194011076036 1.01155288510688 0.10423888186962293 0.037710050914416725 1741.1483029428073 2466959.5824618833 0.015235876292792248 0.012061760195912723 9.603207005208511e-08 7.01758370945227 0.029533483999276466 MAS(ph)NIFGTPEENQASWAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MASNIFGTPEENQASWAK 18 0 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 MAS(0.501)NIFGT(0.498)PEENQASWAK 131.69 9.6613e-06 0.0 27979.0 28767.0 26327.0 32371.0 36961.0 32111.0 38060.0 29866.0 30373.0 26381.0 True False 32715.29208956066 31622.797645520182 26954.73552570351 30557.35781819799 29718.757376758538 30427.042631815217 34454.6812694621 29082.049145642704 30817.147664929325 31163.66646811891 1.0497895721939232 1.0147328998617982 0.8649410862254855 0.9805443736685737 0.9536348172369723 0.9763627352045602 1.1056042235822914 0.933203709370791 0.9888806792504957 1.0 14.927577358911636 -7.025010251251354 24.90232810335048 1.0070168857668726 0.9690571886572175 0.0697462062012395 0.059464243836803606 2046.0594360457237 2037222.9782788523 0.02328735380155578 0.01812310934301647 9.440385925786209e-08 7.025010251251354 -0.03795969710965519 MAS(ph)NIFGTPEENQASWAK ddPTM_PC-9_Lapatinib_30min_R1 2 MASNIFGTPEENQASWAK 18 0 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 MAS(0.555)NIFGT(0.108)PEENQAS(0.337)WAK;MAS(0.874)NIFGT(0.125)PEENQASWAK 162.59 1.6053000000000001e-06 27072000.0 54649.0 41418.0 57644.0 51964.0 55825.0 51378.0 50788.0 41705.0 53503.0 40801.0 True False 53869.695238600776 41322.099165714324 52904.732832274756 55785.605906822406 52541.483256172825 49180.682707967666 53417.55413240744 43642.7665515878 47476.928728432846 47853.39848608485 1.1257235001661456 0.8635144101150989 1.1055585288818885 1.165760586952756 1.0979676453167941 1.027736467291216 1.1162750363057405 0.912009761736746 0.9921328522202769 1.0 15.546333766223455 -7.760177299945015 24.998825725780286 0.9640534800778745 1.0680056218253158 0.254556537267835 0.0810880397703822 49.003489352283545 970712.6717883846 0.04182643151935679 0.02241423355465835 1.7370915194680147e-08 7.760177299945015 0.10395214174744127 MAS(ph)PPAPSPAPPAISPIIK ddPTM_PC-9_AZD4547_30min_R2 2 MASPPAPSPAPPAISPIIK 19 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 MAS(1)PPAPSPAPPAISPIIK;MAS(0.912)PPAPS(0.088)PAPPAISPIIK 105.02 0.00024819999999999996 10219000.0 35718.0 32855.0 42015.0 51623.0 43693.0 47352.0 42162.0 50755.0 50643.0 52933.0 True False 47075.58101944714 43474.7362354573 41457.85364788669 39722.11491739945 37626.981146078935 44391.07195445485 45914.336321383314 42911.980983871654 53319.885590266356 51079.83178155127 0.9216079884673708 0.8511135357959276 0.8116286252700661 0.7776477238076195 0.7366308743340231 0.8690528219493426 0.8988740706457533 0.8400963645962978 1.0438539777948943 1.0 15.64046615344832 -8.25626831465184 24.063217110795932 1.0219270076030207 0.8354967793693725 0.662229246005712 0.05241672012381517 148.12232172896904 689291.67384406 0.041679646753639395 0.014646697514441118 5.542831614157164e-09 8.25626831465184 -0.1864302282336482 MAS(ph)PPAPSPAPPAISPIIK ddPTM_PC-9_Lapatinib_30min_R1 2 MASPPAPSPAPPAISPIIK 19 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 MAS(1)PPAPSPAPPAISPIIK;MAS(1)PPAPSPAPPAISPIIK 202.35 7.9815e-16 9381700.0 45353.0 43803.0 52935.0 44447.0 50647.0 52378.0 51911.0 48138.0 52461.0 44411.0 True False 44706.25790327841 43701.57684474831 48582.88863500913 47715.780650845496 47668.043035833165 50137.91503908151 54598.69757752622 50374.66721640886 46552.289741179295 52087.38217606225 0.8582934299167759 0.8390050530286047 0.9327189542909361 0.9160717751097538 0.9151552841474901 0.9625731404509583 1.0482135076970347 0.9671184289150069 0.8937344860954307 1.0 15.668646311041652 -5.571159283485926 0.714784796657754 0.9749839859888363 0.8243191127738871 0.5398431065865141 0.040906132593393735 1.0407809123385228 0.7990512466305878 0.021479085797227918 0.10814807414818785 2.684359739166711e-06 5.571159283485926 -0.15066487321494915 MASNIFGT(ph)PEENQASWAK ddPTM_PC-9_AZD4547_30min_R2 4 MASNIFGTPEENQASWAK 18 0 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 MASNIFGT(1)PEENQASWAK;MAS(0.001)NIFGT(0.999)PEENQASWAK;MAS(0.017)NIFGT(0.951)PEENQAS(0.032)WAK;MAS(0.408)NIFGT(0.592)PEENQASWAK 167.97 2.5835000000000003e-07 69728900.0 166289.0 141036.0 201603.0 260714.0 244678.0 210666.0 172455.0 245659.0 179565.0 201409.0 True False 219165.44297393036 186623.12889070032 198929.61249493994 200610.4152911469 210708.68314971015 197493.02171729173 187803.16091039707 207698.04623223195 189056.4393107868 194357.7322141287 1.1276394331071449 0.9602042932106917 1.0235230172153598 1.032171002438583 1.0841281216307217 1.0161315398540913 0.9662757368638656 1.0686379382293159 0.9727240442510344 1.0 17.56835497858976 -8.283201546150725 24.73234073602535 0.9863620148651012 1.0306189013503648 0.13362618942299764 0.048429910314357616 1751.9521846104362 1991043.8462204866 0.044565071556725504 0.011554313763807411 5.209528926581418e-09 8.283201546150725 0.0442568864852636 MASNIFGT(ph)PEENQASWAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 MASNIFGTPEENQASWAK 18 0 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 MAS(0.037)NIFGT(0.962)PEENQAS(0.002)WAK;MAS(0.201)NIFGT(0.794)PEENQAS(0.006)WAK;MASNIFGT(0.979)PEENQAS(0.021)WAK;MAS(0.005)NIFGT(0.99)PEENQAS(0.006)WAK 105.06 0.00085895 72703100.0 133833.0 131009.0 146682.0 168769.0 174387.0 160983.0 174613.0 181233.0 159184.0 121556.0 True False 156488.28357776089 144014.70771168167 150179.4551745825 159313.42008648044 140217.1191975537 152540.768085625 158072.3925513551 176475.8257822365 161511.764853459 143593.14056323335 1.0898033357578734 1.0029358446148247 1.0458678916382413 1.1094779281349059 0.9764889788437146 1.0623123603766533 1.1008352622648128 1.2289989973756634 1.1247874670053262 1.0 17.13162730777765 -7.340251104327926 3.5915424685969737 1.136770880705695 1.0447763353470747 0.18474614631159036 0.06371459739822534 0.30176037714113635 7.502368746867319 0.0273540172237847 0.017910176501365598 4.568239826021711e-08 7.340251104327926 -0.0919945453586204 MASNIFGT(ph)PEENQASWAK ddPTM_PC-9_Lapatinib_30min_R1 4 MASNIFGTPEENQASWAK 18 0 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 MAS(0.126)NIFGT(0.873)PEENQAS(0.001)WAK;MAS(0.009)NIFGT(0.99)PEENQASWAK;MAS(0.046)NIFGT(0.954)PEENQASWAK;MAS(0.015)NIFGT(0.985)PEENQASWAK 145.71 0.0003148 36509000.0 223019.0 171783.0 203966.0 177167.0 190264.0 196646.0 181925.0 161666.0 214783.0 169731.0 True False 219838.70816332422 171385.2470178163 187196.70281152884 190196.4521917866 179073.04559341617 188235.9089842151 191344.1863341383 169177.59255074942 190591.87677474166 199068.77719765904 1.1043354525910527 0.8609348458881864 0.9403619464927833 0.9554308559545581 0.899553652331984 0.9455822838420924 0.961196371564332 0.8498449376758359 0.9574172276423815 1.0 17.602907434749675 -4.747832761913586 24.964796489871034 0.9269667661143928 1.1043358979209303 0.5788892159723392 0.04452909621985578 458.56508453831464 841304.6256075277 0.01039262043116651 0.2021735372583847 1.787175647825996e-05 4.747832761913586 0.17736913180653757 MASPPAPS(ph)PAPPAISPIIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MASPPAPSPAPPAISPIIK 19 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 MAS(0.194)PPAPS(0.805)PAPPAISPIIK 80.318 0.0022131 8557400.0 47280.0 50776.0 50824.0 53690.0 51216.0 45045.0 60058.0 56275.0 44994.0 38671.0 True False 55283.570177434085 55816.70571310646 52035.83691109337 50681.92336532858 41180.59245713227 42682.7609028095 54368.87145773399 54797.840878291194 45651.95212971489 45681.74618053242 1.2101895133114142 1.2218601603476602 1.1390947426889033 1.10945678751061 0.9014671263744654 0.9343504675615716 1.1901662261961354 1.1995566163721574 0.9993477908944245 1.0 15.479330178189036 -5.647145731243539 2.3124557371207213 1.0489300128803394 1.2127732589359885 0.36061418507329934 0.09212730254832548 0.38343667473309806 4.137378528658554 0.03020171115963302 0.06300681620631653 2.2534829097222157e-06 5.647145731243539 0.16384324605564915 MASSHWNETT(ph)TS(ph)VYQYLGFQVQK ddPTM_PC-9_Lapatinib_30min_R1 1 MASSHWNETTTSVYQYLGFQVQK 23 0 P0DKX4 P0DKX4 SMIM18 Small integral membrane protein 18 2 MAS(0.007)S(0.007)HWNET(0.053)T(0.467)T(0.467)S(0.528)VY(0.419)QY(0.051)LGFQVQK 47.047 0.036029000000000005 4132500.0 4098.4 3142.4 4256.5 4882.2 5030.7 4662.6 5170.7 5142.2 3800.4 4019.2 True False 4039.9560644454873 3135.1239658684804 3906.5470005651496 5241.253274541764 4734.80411673674 4463.191467051466 5438.413545570594 5381.125384524031 3372.3589320138362 4713.913364752636 0.8570280681553182 0.6650788258670081 0.8287269405024686 1.1118688166253137 1.0044317216647023 0.9468123662229574 1.1536939957860206 1.1415410017418526 0.7154053693964743 1.0 12.202709528742258 -5.610368403527477 5.4965853352186045 1.018636152598354 0.7576343703923747 0.41025422233907094 0.12591803769234355 0.17836543666804242 8.627020054212771 0.033786662366174405 0.05964701766770441 2.4526275169806582e-06 5.610368403527477 -0.26100178220597936 MATADTPAPAS(ph)S(ph)GLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 MATADTPAPASSGLSPK 17 0 O60293-2;O60293;G3V1X1;O60293-4 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 3 MAT(0.008)ADT(0.032)PAPAS(0.971)S(0.989)GLS(1)PK 71.316 0.031541 0.0 559.93 681.5 6881.9 13305.0 9577.8 4533.3 2953.0 11261.0 2974.4 5219.6 True False 737.9760927324885 901.7815475411402 6790.641509446416 10237.737810200873 8248.087794862213 4249.832034362438 3215.8112792809884 9520.871202036813 3131.6207116420514 5036.863392722592 0.1465150104723384 0.17903633218325132 1.3481885411579226 2.0325621347985448 1.6375444699928317 0.8437457407526121 0.6384551314072339 1.8902381223586184 0.6217402513172601 1.0 12.298309888138983 -5.258951236625676 23.564802541474158 1.288570352108282 0.16277535130020768 0.4626942977728896 0.4679581154997032 82.37748536954915 780153.3512667399 0.12485578283062267 0.29954416779047466 5.508695455675694e-06 5.258951236625676 -1.1257950008080744 MATEVAADALGEEWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MATEVAADALGEEWK 15 0 P62753;A2A3R5;A2A3R7 P62753 RPS6 40S ribosomal protein S6 0 107.45 0.0052054 0.0 5404.8 4111.4 5392.3 6479.3 7855.1 6394.7 6916.4 5474.3 5446.5 5596.6 False True 6319.72589033409 4519.552620703989 5520.87288241163 6116.28582717402 6315.949543307164 6059.350674774021 6261.2285216003065 5330.605425500303 5526.144758734323 6611.219277338776 0.9559092846906718 0.6836186232992791 0.835076352910496 0.925137341630577 0.9553380818809466 0.9165254426734278 0.9470610879693357 0.8062968723140037 0.8358737665344493 1.0 12.690700650669449 -5.642087409906037 5.225339844669067 0.9073405289347732 0.80613224221859 0.19090740419152186 0.08110422766473081 0.3069757687014059 12.70647252874054 0.021985279948235986 0.03874750393152147 2.2798831565939326e-06 5.642087409906037 -0.1012082867161832 MATEVAADALGEEWK ddPTM_PC-9_Lapatinib_30min_R1 4 MATEVAADALGEEWK 15 0 P62753;A2A3R5;A2A3R7 P62753 RPS6 40S ribosomal protein S6 0 ;;; 196.7 1.4751e-14 10199900.0 53452.9 53003.399999999994 52340.299999999996 49192.1 56046.799999999996 45808.9 52988.1 51066.8 52516.3 55436.5 False True 52690.65184393865 52880.67388381917 48037.082573400745 52809.85113403507 52750.23741624841 43849.76013276152 55731.56454523547 53439.549956518924 46601.36127284449 65018.625160506956 0.8103932021611485 0.8133157807209292 0.7388203373235737 0.8122265120750718 0.8113096406764612 0.6744184458609002 0.857163073006463 0.8219114111471355 0.7167386446237975 1.0 15.988565429655093 -11.581089598860137 2.32849957376471 1.2934188662754778 0.7852369492679296 0.5957514003438389 0.053362091785985964 14123792.128434995 4651940.036593874 22036872.877830952 0.012931698373017563 2.6236771993257557e-12 11.581089598860137 -0.5081819170075481 MAVNVY(ph)STSVTS(ph)DNLS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 MAVNVYSTSVTSDNLSR 17 0 Q15691 Q15691 MAPRE1 Microtubule-associated protein RP/EB family member 1 3 MAVNVY(0.831)S(0.104)T(0.118)S(0.127)VT(0.16)S(0.692)DNLS(0.967)R 55.755 0.022806 19865000.0 0.0 0.0 0.0 0.0 708.89 883.53 0.0 1033.5 0.0 0.0 True False 0.0 0.0 0.0 0.0 610.4728598320983 828.2827294289472 0.0 873.7963224673692 0.0 0.0 0.0 MAVNVY(ph)STSVTS(ph)DNLS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 MAVNVYSTSVTSDNLSR 17 0 Q15691 Q15691 MAPRE1 Microtubule-associated protein RP/EB family member 1 3 MAVNVY(0.466)S(0.285)T(0.309)S(0.079)VT(0.083)S(0.846)DNLS(0.932)R 47.09 0.046 21628000.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MAVS(ph)TEELEAT(ph)VQEVLGRLK ddPTM_PC-9_AZD4547_30min_R2 1 MAVSTEELEATVQEVLGRLK 20 1 A0A4V7I672;K7EJ46;K7EJ46-2 A0A4V7I672 SMIM22 Small integral membrane protein 22 2 MAVS(0.501)T(0.501)EELEAT(0.998)VQEVLGRLK 54.073 0.020544 10548000.0 22739.0 20421.0 27087.0 38928.0 34704.0 29898.0 29117.0 32506.0 27708.0 26673.0 True False 29969.528999417897 27021.688895579784 26727.808681668594 29953.75103160461 29885.948634644497 28028.473333635146 31708.356592896882 27482.94461356973 29172.58831299689 25739.186388629343 1.1643541698216757 1.0498268471888064 1.0384092285634945 1.1637411757831286 1.1611069667628284 1.0889416980956759 1.2319098247372926 1.067747216194476 1.1333920145154355 1.0 14.651678830480202 -4.439332700614953 19.726672544704293 1.1109194136410276 3.5409512168499524 0.0606271108391615 0.06640228158440523 439.82669019659875 109864.29813346679 0.015753432874072073 2749.094232112603 3.6363635795551756e-05 4.439332700614953 2.4300318032089248 MCFGLAFMLAGVILGGAYLYK ddPTM_PC-9_Lapatinib_30min_R1 1 MCFGLAFMLAGVILGGAYLYK 21 0 A0A3B3IUC0 A0A3B3IUC0 0 50.387 0.035838999999999996 17910000.0 22253.0 10416.0 10031.0 13355.0 10023.0 7910.7 6422.7 4869.9 10523.0 5646.9 False True 21935.668139299592 10391.882391957128 9206.28990077976 14337.171250974 9433.466845976176 7572.3778017423765 6755.235979487547 5096.173332444004 9337.788927897484 6622.959140978718 3.3120645428076756 1.5690693798273156 1.3900568771166066 2.164768186816158 1.4243583034670708 1.1433526374772949 1.0199724678490592 0.7694707492474291 1.4099119032942693 1.0 12.693260242502264 -1.5228787476837229 0.6720149751791588 1.168414723922246 199.99999965475718 0.7321966181118178 0.3620027238151377 140.22609892566322 0.831536002042599 0.1577451876464436 41674.98894648415 0.029999999833980023 1.5228787476837229 198.83158493083494 up MCHNVNR ddPTM_PC-9_AZD4547_30min_R2 3 MCHNVNR 7 0 P49915-2;P49915 P49915-2 GMPS GMP synthase [glutamine-hydrolyzing] 0 ;; 106.76 0.0056405 5535900.0 22153.16 13818.54 18950.2 25474.0 23002.5 19261.89 18606.2 22513.8 24812.8 29046.5 False True 29197.40406564689 18285.11281872214 18698.907966159277 19601.362869376684 19808.999927051926 18057.44097332308 20262.115755014536 19034.80952565638 26124.353951664816 28029.59087606653 1.041663583130552 0.6523503286070133 0.6671131251553731 0.6993096315977123 0.706717412131981 0.6442277753237449 0.7228830361671684 0.6790969447188587 0.9320276584547466 1.0 14.774663066289548 -8.370835874599177 4.086489524171446 0.9948765682399137 0.7178455540501258 0.43546466825030006 0.1095225658948297 0.1970110219624482 5.305850570157751 0.10130203050518306 0.026780122224982397 4.257592825751149e-09 8.370835874599177 -0.2770310141897878 MCHNVNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 MCHNVNR 7 0 P49915-2;P49915 P49915-2 GMPS GMP synthase [glutamine-hydrolyzing] 0 ;; 103.28 0.0071960999999999995 2812560.0 6686.49 8838.04 7494.820000000001 6650.58 11877.09 10471.9 6353.549999999999 7044.8099999999995 7211.1 8597.83 False True 7818.380692802692 9715.422202628477 7673.524933063136 6277.969564071275 9549.859474903953 9922.735129273631 5751.69574828142 6859.891202093188 7316.548695439108 10156.54851861517 0.7697871652434852 0.9565673008721234 0.7555248634906742 0.6181203735269771 0.9402662191196878 0.9769790506181307 0.5663041669854253 0.6754155892151956 0.7203774670134405 1.0 13.310122596516027 -7.260559984072427 24.99996577952853 0.7134756126839193 0.8328278893660558 0.08326688337802524 0.14454586891664395 171.91852840194323 4887507.881088167 0.05786978302637722 0.04219007782806027 5.4883274645403e-08 7.260559984072427 0.11935227668213644 MCHNVNR ddPTM_PC-9_Lapatinib_30min_R1 5 MCHNVNR 7 0 P49915-2;P49915 P49915-2 GMPS GMP synthase [glutamine-hydrolyzing] 0 ;;;; 105.27 0.0069394999999999995 8581460.0 29343.9 25480.8 27554.29 23935.1 26865.13 25650.6 26814.899999999998 26975.899999999998 32552.999999999996 22447.0 False True 28925.4506049878 25421.800773135674 25288.882638835283 25695.36709915295 25284.975872277773 24553.583632469083 28203.24431568664 28229.298794364637 28886.538341713072 26326.934041252607 1.0987018298318934 0.965619495733964 0.9605707447441177 0.9760106155502182 0.9604223504589576 0.9326412104803089 1.0712696082078519 1.0722592592867497 1.0972237897679133 1.0 14.684251898615555 -7.279936545847775 24.471365234697004 1.0662097836203457 0.979296452534401 0.3868120316509782 0.04769370987832721 616.6542938260404 815817.0512413346 0.01979124614175055 0.013373264534147474 5.2488414472718175e-08 7.279936545847775 -0.08691333108594468 MCS(ph)PSPDATSGTGSQR ddPTM_PC-9_AZD4547_30min_R2 2 MCSPSPDATSGTGSQR 16 0 A0A2R8Y589;A0A2R8Y4C1;A0A2R8Y7U5;A8MST6;A0A2U3TZI9;A0A2R8Y5W6;A0A2R8Y432;A0A2R8YCP0;A0A2R8Y7A4;Q5JTW2;Q5JTW2-3;Q5JTW2-5;Q5JTW2-2 A0A2R8Y589 CEP78 Centrosomal protein of 78 kDa 1 MCS(0.972)PS(0.024)PDAT(0.003)S(0.001)GTGSQR;MCS(0.5)PS(0.5)PDATSGTGSQR 110.22 0.00052466 2428870.0 6602.1 6218.7 10990.0 12644.900000000001 12641.1 12337.8 11412.0 17374.3 12572.8 14269.4 True False 8701.430467789118 8228.773161693447 10844.265419261565 9729.813666757536 10886.101466269152 11566.315415603836 12427.645892026625 14689.501156695509 13237.372540120083 13769.832649267333 0.6319198416875534 0.5975942752021234 0.7875379240602876 0.7066036250829266 0.7905761633819407 0.8399750171414944 0.9025270102093708 1.0667886481160038 0.9613314030235813 1.0 13.749223405431968 -6.724127375952724 0.6049869734446585 1.0321072374519862 0.6215210554882097 0.8759844708945445 0.05216054547963501 0.27334158869233915 0.2188868445929045 0.04257407286700884 0.04976221920111352 1.8874376938141348e-07 6.724127375952724 -0.4105861819637765 MCS(ph)PSPDATSGTGSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MCSPSPDATSGTGSQR 16 0 A0A2R8Y589;A0A2R8Y4C1;A0A2R8Y7U5;A8MST6;A0A2U3TZI9;A0A2R8Y5W6;A0A2R8Y432;A0A2R8YCP0;A0A2R8Y7A4;Q5JTW2;Q5JTW2-3;Q5JTW2-5;Q5JTW2-2 A0A2R8Y589 CEP78 Centrosomal protein of 78 kDa 1 MCS(0.998)PS(0.002)PDATSGTGSQR 90.725 0.018619999999999998 0.0 2774.2 2368.2 3503.5 3253.2 3390.0 4161.9 3562.1 4370.6 3860.8 2371.5 True False 3243.8172670524013 2603.2992451114424 3587.0367270977417 3070.9337510167056 2725.753835318618 3943.642637393781 3224.672100629294 4255.876381033484 3917.2568960839944 2801.4341772163275 1.1579130766069443 0.9292737506680369 1.280428701937961 1.0962005732607178 0.9729851436406369 1.407722754818541 1.1510790176171553 1.5191777182008885 1.3983041000722047 1.0 11.451949879918324 -6.765677073564147 24.999527946688033 1.318694225214976 1.0897948176906405 0.28466186683509753 0.16265064798917975 129.55017149736787 764252.9617331154 0.054470855318910334 0.049714684167274356 1.7152322211297927e-07 6.765677073564147 -0.22889940752433557 MCS(ph)PSPDATSGTGSQR ddPTM_PC-9_Lapatinib_30min_R1 2 MCSPSPDATSGTGSQR 16 0 A0A2R8Y589;A0A2R8Y4C1;A0A2R8Y7U5;A8MST6;A0A2U3TZI9;A0A2R8Y5W6;A0A2R8Y432;A0A2R8YCP0;A0A2R8Y7A4;Q5JTW2;Q5JTW2-3;Q5JTW2-5;Q5JTW2-2 A0A2R8Y589 CEP78 Centrosomal protein of 78 kDa 1 MCS(0.976)PS(0.024)PDATSGTGSQR;MCS(0.984)PS(0.015)PDATSGTGSQR 111.81 0.0030482 0.0 11545.6 8460.7 11411.1 9614.3 10869.3 10084.5 8615.3 7361.6 9783.8 9860.9 True False 11380.95762679627 8441.109768973854 10472.923406119822 10321.36769436461 10229.989143865994 9653.20944311768 9061.35807901335 7703.646810842071 8681.845416018565 11565.343426176678 0.9840570407132853 0.7298624396979411 0.9055436592064959 0.8924393607718999 0.8845382940131047 0.8346669084870296 0.7834923482258316 0.66609754046783 0.7506777011366836 1.0 13.497520486153535 -7.115354991509325 3.0389732014868054 0.7720786567875366 0.8725538100341753 0.09763738080348461 0.09910977818344333 0.4656555996978852 8.204064550564429 0.03945749751047933 0.029767373166517896 7.66734505776792e-08 7.115354991509325 0.1004751532466387 MDAMLLR ddPTM_PC-9_AZD4547_30min_R2 1 MDAMLLR 7 0 A6NKX1 REV__Q86WC4 FAM223B Protein FAM223B 0 54.787 0.045877999999999995 0.0 553.86 835.53 2043.5 2439.1 2011.9 2228.4 1067.5 1228.5 1037.4 842.98 False True 729.9759589963315 1105.5987328203203 2016.4018548008196 1876.8031787193495 1732.5824129218915 2089.0577957278924 1162.5054319784804 1038.6635531215898 1092.234846105925 813.467526783143 0.8973633672668179 1.3591184606869435 2.478773630675437 2.307164228351151 2.1298728663126703 2.5680899691092414 1.4290741716213402 1.276834684758695 1.3426901629683576 1.0 9.667940945157467 -7.490912433105859 15.731711123643466 1.2564314998275148 1.9788987076009736 0.3346651380757113 0.4852868179872994 9.709206585233108 4778.600631840609 0.22335880512843218 0.14968371196977204 3.2291451493403093e-08 7.490912433105859 0.7224672077734589 MDAPASGSACSGLNKQEPGGSHGS(ph)ETEDTGR ddPTM_PC-9_AZD4547_30min_R2 1 MDAPASGSACSGLNKQEPGGSHGSETEDTGR 31 1 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 MDAPAS(0.003)GS(0.009)ACS(0.003)GLNKQEPGGS(0.075)HGS(0.883)ET(0.027)EDTGR 75.119 0.00010712 0.0 10630.0 4666.5 12427.0 28845.0 19924.0 14273.0 7512.5 12589.0 7743.7 14098.0 True False 14010.118882264487 6174.8548666188235 12262.209860342438 22195.23090080751 17157.8965132739 13380.507053681655 8181.097946359095 10643.659316440944 8153.016172923123 13604.433311097238 1.0298201006899954 0.45388548904730547 0.9013392605144429 1.631470447409426 1.2611989136863258 0.9835401995588507 0.6013552905350135 0.7823669735481618 0.5992911271263792 1.0 13.731789242326155 -7.123344184744949 5.6985093152897655 0.7296376257043525 1.0523376426047528 0.19830636807071056 0.2950457559981741 0.424756579678309 18.021178565425718 0.1268897559599514 0.09805180271417055 7.527587549241432e-08 7.123344184744949 0.3227000169004003 MDAPASGSACSGLNKQEPGGSHGS(ph)ETEDTGR ddPTM_PC-9_Lapatinib_30min_R1 1 MDAPASGSACSGLNKQEPGGSHGSETEDTGR 31 1 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 MDAPAS(0.048)GS(0.048)ACS(0.048)GLNKQEPGGS(0.145)HGS(0.658)ET(0.048)EDT(0.003)GR 56.46 0.0050522 0.0 12613.0 3693.6 7424.3 6948.5 3971.2 5863.5 3340.1 2667.4 5997.2 3789.2 True False 12433.136307059078 3685.047696134107 6813.9027126267765 7459.5158695164955 3737.6218236795994 5612.731773486093 3513.034034765183 2791.3371418224488 5321.732182684291 4444.158171208374 2.797635868949841 0.8291891409283788 1.5332268677498633 1.67849918525475 0.84101908161008 1.2629459972528343 0.7904835740375962 0.6280913131999258 1.1974668717151673 1.0 12.1176944489942 -4.755987805439509 24.999812505865297 1.094282213702481 2.797638556294622 0.7201558176284164 0.3203139706490395 99.64633533760802 456909.51199474756 0.08480181394424156 0.7158096599473684 1.7539297497669406e-05 4.755987805439509 1.703356342592141 MDAPASGSACSGLNKQEPGGSHGSET(ph)EDTGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MDAPASGSACSGLNKQEPGGSHGSETEDTGR 31 1 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 MDAPASGSACSGLNKQEPGGS(0.003)HGS(0.253)ET(0.564)EDT(0.18)GR;MDAPASGSACSGLNKQEPGGS(0.271)HGS(0.271)ET(0.454)EDT(0.004)GR 65.152 9.735200000000001e-05 9213300.0 7376.4 1028.9 9343.1 12276.4 12292.900000000001 15355.3 9939.5 15217.3 12232.2 8408.3 True False 8625.078829459066 1131.0423922367893 9565.87493790406 11588.593108625804 9884.194490321013 14550.04103653925 8997.958604251668 14817.861999062108 12411.072783951162 9932.658229933817 0.8683555428763138 0.11387106714577107 0.9630729978280748 1.1667161841632219 0.9951207684296688 1.4648687893730337 0.905896326638395 1.4918324637815352 1.2495217792300761 1.0 13.27796415568098 -5.471786014921157 5.24109968175288 1.187746610802773 0.4909157850465896 0.5486600898233784 0.24739412747526293 0.1342290202799366 8.235902620916969 0.0618366002496728 0.12848260872137496 3.374535374232708e-06 5.471786014921157 -0.6968308257561834 MDATANDVPSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MDATANDVPSDR 12 0 A0A499FI48;P13667 A0A499FI48 PDIA4 Protein disulfide-isomerase A4 0 95.477 0.018462 0.0 7020.1 8568.4 9932.2 7575.2 8849.0 8234.4 11243.0 6566.9 5384.2 9649.5 False True 8208.464276704843 9419.014125417154 10169.021316078257 7150.786103129762 7115.101973078007 7802.573568167263 10177.981647728908 6394.52583320569 5462.933739094344 11398.877964600031 0.7201116024047955 0.8263106381758384 0.8921072185928145 0.6273236826762248 0.6241931877132492 0.6845036496046953 0.8928932899656705 0.5609785325419144 0.479251883918737 1.0 13.476604200906593 -5.767595946489151 24.988682742156527 0.6820833885665532 0.814189904356145 0.11020440886098737 0.14924588284659338 287.5565693640092 1167158.7994059478 0.04156713008349524 0.06344375525985076 1.7076704113729025e-06 5.767595946489151 0.13210651578959187 MDCQECPEGYR ddPTM_PC-9_Lapatinib_30min_R1 3 MDCQECPEGYR 11 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ;; 112.71 0.011375 11393100.0 23391.3 31522.0 36037.0 28008.9 30334.7 34952.9 28679.899999999998 36270.4 33003.3 24220.800000000003 False True 23057.735772560933 31449.01274570592 33074.17696684281 30068.76794095138 28550.47258631485 33458.0459461895 30164.80489017154 37955.655195605075 29286.12081384387 28407.333007812664 0.8116825245868569 1.1070737522968708 1.1642830728863796 1.0584861286584624 1.0050388249563174 1.1777960971199857 1.061866838462996 1.3361217395933087 1.0309352449872546 1.0 14.793975771548087 -6.760914404734985 24.999998929911328 1.13863427360042 1.0427519899934101 0.11045426833716465 0.12297023311869625 31.109401930330627 1481510.8367836901 0.04115000279540723 0.038765502740439446 1.7341457475217665e-07 6.760914404734985 -0.0958822836070099 MDEERSSMLPTMAAGPNS(ph)ILFAINIDNK ddPTM_PC-9_Lapatinib_30min_R1 1 MDEERSSMLPTMAAGPNSILFAINIDNK 28 1 Q8IUI4 Q8IUI4 SNX29P2 Putative protein SNX29P2 1 MDEERS(0.04)S(0.04)MLPT(0.013)MAAGPNS(0.906)ILFAINIDNK 48.115 0.044905 0.0 2960.6 3671.2 3588.6 6101.4 5678.1 5019.3 5622.5 5117.6 4944.2 3379.1 True False 2918.381301092455 3662.6995619578547 3293.559160396595 6550.117309673735 5344.125321574116 4804.636239559778 5913.605538896217 5355.382378717318 4387.332131265868 3963.1729326322743 0.736374957817981 0.9241836337242922 0.8310409907369516 1.6527457723938517 1.3484461597855726 1.212320613112539 1.4921391620850866 1.3512865751130272 1.1070251553095551 1.0 11.952440205187186 -5.734872257463617 24.99911382803502 1.3290034352777833 0.8398977630145399 0.5980039850764635 0.1792565373742019 143.8820745310612 135388.96144797897 0.04717253899730168 0.08167525733640656 1.8413135222114279e-06 5.734872257463617 -0.4891056722632434 MDFAFPGS(ph)TNSLHR ddPTM_PC-9_Lapatinib_30min_R1 3 MDFAFPGSTNSLHR 14 0 P16144-4;P16144-2;P16144-3;P16144 P16144-4 ITGB4 Integrin beta-4 1 MDFAFPGS(0.562)T(0.27)NS(0.168)LHR;MDFAFPGS(0.447)T(0.371)NS(0.182)LHR;MDFAFPGS(0.453)T(0.273)NS(0.273)LHR 105.28 0.00068406 42901900.0 423420.0 383030.0 181756.0 103147.0 183315.0 132339.0 98675.0 94794.0 260958.0 63619.0 True False 417381.9531542818 382143.11756829266 166812.72327844918 110732.774468305 172532.7721111567 126679.16946727669 103783.90867951687 99198.47530251072 231566.1620304355 74615.45938301105 5.593773148427658 5.121500567418628 2.2356321954968785 1.4840460058002052 2.3122925669534924 1.6977603638009613 1.390916969991169 1.3294627698170667 3.1034609174189445 1.0 16.18718694923341 -5.265347241743946 3.379680556074344 1.778551144009402 5.526065547751675 0.8674661918743077 0.5572698423863365 0.07301609444082101 1.7618843522603143 0.143610226173992 0.3976836872052026 5.428161472997245e-06 5.265347241743946 3.747514403742273 MDFAFPGST(ph)NSLHR ddPTM_PC-9_AZD4547_30min_R2 2 MDFAFPGSTNSLHR 14 0 P16144-4;P16144-2;P16144-3;P16144 P16144-4 ITGB4 Integrin beta-4 1 MDFAFPGS(0.271)T(0.686)NS(0.043)LHR;MDFAFPGS(0.004)T(0.635)NS(0.361)LHR 107.51 0.00077308 29553100.0 38433.0 75235.0 90322.0 104576.0 117743.0 82319.0 91180.0 132248.0 86271.0 83305.0 True False 50653.89454393898 99553.24244938772 89124.27126465364 80467.6188830941 101396.41684212028 77171.57991676725 99294.84336093494 111812.11035671455 90831.1089342629 80388.51730606858 0.6301135565304808 1.2384012765200283 1.1086691762870167 1.000983990993693 1.2613296057702734 0.9599826256646423 1.2351868984333054 1.390896537262963 1.1299015329320672 1.0 16.2947018211442 -4.755805259901119 24.999820725303113 1.1541595043553017 0.6301127210631078 0.5873812083005997 0.12991628363484853 129.50547029245428 574584.8128258535 0.03245345546241706 0.27864960495598884 1.7546671281165695e-05 4.755805259901119 -0.5240467832921939 MDFAFPGST(ph)NSLHR ddPTM_PC-9_Lapatinib_30min_R1 2 MDFAFPGSTNSLHR 14 0 P16144-4;P16144-2;P16144-3;P16144 P16144-4 ITGB4 Integrin beta-4 1 MDFAFPGS(0.03)T(0.565)NS(0.405)LHR;MDFAFPGS(0.104)T(0.497)NS(0.399)LHR 100.45 0.0019527999999999998 21822800.0 230451.0 219532.0 93023.0 71713.1 102455.0 69355.9 50980.8 49896.1 122354.0 25297.9 True False 227164.72648046256 219023.68714200536 85375.00801916419 76987.12060188879 96428.79833428022 66389.70983349941 53620.33637302983 52214.45496066848 108573.20407526064 29670.608307667128 7.656220732817309 7.381840131852229 2.8774269517454614 2.5947267344024993 3.2499771266692306 2.2375580960483297 1.8071869581175353 1.7598039925314184 3.6592847355679066 1.0 14.85674688484617 -5.273430026792748 3.9816346402598035 2.3954447682850537 7.659890893752921 0.8921933041240117 0.7142062655513767 0.058305041970781984 2.1761025002278718 0.1867141041161419 0.47690952218244936 5.328070628894412e-06 5.273430026792748 5.264446125467868 MDFAFPGSTNS(ph)LHR ddPTM_PC-9_AZD4547_30min_R2 6 MDFAFPGSTNSLHR 14 0 P16144-4;P16144-2;P16144-3;P16144 P16144-4 ITGB4 Integrin beta-4 1 MDFAFPGS(0.001)T(0.021)NS(0.978)LHR;MDFAFPGS(0.016)T(0.318)NS(0.665)LHR;MDFAFPGS(0.228)T(0.283)NS(0.489)LHR;MDFAFPGS(0.002)T(0.08)NS(0.918)LHR;MDFAFPGS(0.391)T(0.21)NS(0.399)LHR;MDFAFPGS(0.272)T(0.181)NS(0.547)LHR 116.51 9.9486e-05 81914200.0 145765.0 273893.0 352059.0 431780.0 456443.0 334244.0 359903.0 478283.0 314741.0 291739.0 True False 192115.23789965053 362423.555980463 347390.46762873564 332239.791934501 393073.7682296873 313343.6698417126 391933.66977550415 404375.35219996126 331377.56670351326 281525.30640844 0.6824084141868498 1.2873569364121566 1.233958225853905 1.1801418358194906 1.396228897658712 1.113021326001543 1.3921791784035304 1.4363730115732085 1.1770791440778936 1.0 18.1029050869341 -4.759951246853676 24.99619302847048 1.2625287230159723 0.6824077035304181 0.6230095543183503 0.13103533039378248 23.141764016248874 388580.9107781533 0.030905689146355667 0.18945662281054568 1.7379959222106954e-05 4.759951246853676 -0.5801210194855542 MDFAFPGSTNS(ph)LHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 MDFAFPGSTNSLHR 14 0 P16144-4;P16144-2;P16144-3;P16144 P16144-4 ITGB4 Integrin beta-4 1 MDFAFPGS(0.315)T(0.251)NS(0.434)LHR;MDFAFPGS(0.018)T(0.25)NS(0.733)LHR;MDFAFPGS(0.055)T(0.201)NS(0.744)LHR;MDFAFPGS(0.033)T(0.421)NS(0.546)LHR;MDFAFPGS(0.08)T(0.294)NS(0.626)LHR;MDFAFPGS(0.058)T(0.27)NS(0.672)LHR 118.23 8.2225e-05 123434500.0 324852.0 337549.0 510086.0 419938.0 1019794.0 471198.0 382682.0 423506.0 413996.0 391274.0 True False 379843.02748053696 371058.6339363747 522248.3847519264 396410.23531736544 819972.6863524808 446487.5473833286 346431.5905822469 412389.4162416976 420049.90829651593 462208.8788767196 0.821799504162811 0.8027942579513784 1.129896911589231 0.8576430558424993 1.7740305818988473 0.9659865220858637 0.7495130587369074 0.8922143971874892 0.908788055559079 1.0 18.818185448193844 -6.995290422393237 24.998395750358466 0.8756613815736444 1.0844421270104214 0.100925066898645 0.26647471417875296 311.22141484113 1651946.9527485943 0.09843536892632035 0.08650253118591464 1.0109032146810184e-07 6.995290422393237 0.20878074543677705 MDFAFPGSTNS(ph)LHR ddPTM_PC-9_Lapatinib_30min_R1 4 MDFAFPGSTNSLHR 14 0 P16144-4;P16144-2;P16144-3;P16144 P16144-4 ITGB4 Integrin beta-4 1 MDFAFPGS(0.019)T(0.063)NS(0.918)LHR;MDFAFPGS(0.042)T(0.237)NS(0.721)LHR;MDFAFPGS(0.037)T(0.102)NS(0.861)LHR;MDFAFPGS(0.131)T(0.095)NS(0.774)LHR 102.36 0.0010266 20481100.0 366498.0 336754.0 173889.0 90006.0 159998.0 105972.0 76919.0 82471.0 225767.0 49014.2 True False 361271.6713124974 335974.2668031046 159592.5176509512 96625.3414912142 150587.23220817078 101439.82459279742 80901.48945244253 86302.9037351877 200338.74302809374 57486.23916268376 6.284489585239921 5.844429409485474 2.776186440015857 1.6808429790957162 2.619535290559101 1.764593162995526 1.4073192233622127 1.5012793494970844 3.4849860757309776 1.0 15.810929030081315 -5.297173954472611 2.8714908409025752 1.948407762690672 6.2796159319458535 0.8603258012131071 0.6589758401434846 0.0864855163668889 1.4015059195039898 0.1748583027530257 0.49893046618987297 5.044591984940485e-06 5.297173954472611 4.331208169255182 MDGEATS(ph)PLPR ddPTM_PC-9_Lapatinib_30min_R1 2 MDGEATSPLPR 11 0 Q86UU1-3;Q86UU1-2;Q86UU1;A0A087WZL0 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 MDGEAT(0.24)S(0.76)PLPR;MDGEAT(0.432)S(0.568)PLPR 80.834 0.013849 8178200.0 42514.0 61959.0 68021.0 64570.0 67796.0 70358.0 77869.0 63870.0 73640.0 58381.0 True False 41907.742563887245 61815.537742249646 62428.57594865313 69318.69319920555 63808.37257206442 67348.95235250858 81900.6758040568 66837.6333688984 65345.88773642219 68472.07806220737 0.6120413422506874 0.9027846020109072 0.91173771434155 1.0123643850304795 0.9318889447767901 0.9835973181845246 1.1961178647104802 0.9761297635537795 0.9543435745743687 1.0 16.063228177061248 -4.295857583533036 0.9938777514419583 1.0124000938521673 2.6515961225188927e-16 0.7257632926528139 0.07161068112393137 2.4472263651861565 0.9994463027247363 0.02409711769609365 3.33597332341001 5.059905622783603e-05 4.295857583533036 -1.0124000938521671 MDGT(ph)YACSYTPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MDGTYACSYTPVK 13 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 1 MDGT(0.455)Y(0.067)ACS(0.294)Y(0.006)T(0.178)PVK 85.53299999999999 0.030729000000000003 6796300.0 37924.0 39900.0 45157.0 50770.0 52094.0 37745.0 47537.0 45199.0 38706.0 29681.0 True False 44343.78416685721 43861.00831008639 46233.71413887617 47925.521498560855 41886.55465990801 35765.58575372502 43033.951221923795 44012.57414229913 39272.00202544217 35061.93034533326 1.2647274046267496 1.2509581725275514 1.318630026456312 1.3668820006922333 1.1946448540441843 1.0200689295044878 1.2273697083438422 1.2552809759419647 1.1200752964438327 1.0 15.097617805851588 -6.511016949471972 24.333230754288124 1.1425416241655 1.2959192639668262 0.5103702874882514 0.08017125252351061 383.4440813439291 786597.2936623855 0.02613533998890616 0.028076625419532472 3.083067623166747e-07 6.511016949471972 0.15337763980132624 MDGTYACS(ph)YTPVK ddPTM_PC-9_AZD4547_30min_R2 1 MDGTYACSYTPVK 13 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 1 MDGT(0.008)Y(0.009)ACS(0.744)Y(0.004)T(0.235)PVK 97.273 0.0026884 6476700.0 42875.0 37632.0 49259.0 77011.0 61045.0 55681.0 45044.0 70767.0 47977.0 56560.0 True False 56508.35814459926 49795.80806613081 48605.79347474117 59257.30375808934 52569.955463401144 52199.25826778175 49052.828738209544 59831.5862138832 50512.96627301326 54579.85161552414 1.0353336711623928 0.9123478095343044 0.8905446247295445 1.0856992462257775 0.9631751261201429 0.9563832938844913 0.8987351062027705 1.0962211226837655 0.9254874239827701 1.0 15.736080851958526 -7.740992616057434 24.999557499078733 1.0081408545512267 0.9628772095003003 0.07987119163494283 0.06850759345295557 616.7487968481033 754079.2811119434 0.031806593214387134 0.018336638470994995 1.8155465307162104e-08 7.740992616057434 -0.04526364505092639 MDGTYACSYT(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 1 MDGTYACSYTPVK 13 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 1 MDGTYACS(0.249)Y(0.043)T(0.707)PVK 94.53200000000001 0.014303 6684400.0 59754.0 36935.0 55833.0 73427.0 66168.0 52788.0 59526.0 64735.0 53095.0 71707.0 True False 78754.52903958914 48873.51644670875 55092.61793936589 56499.539585841296 56981.71534281802 49487.15801511579 64823.69868285814 54731.69321231271 55901.49330440919 69196.55975591214 1.1381278103621382 0.7062998018847753 0.796175678873382 0.8165079273469804 0.8234761315276156 0.7151678954803474 0.9368052242990248 0.7909597443193186 0.8078652103746093 1.0 16.078412692751606 -10.114252755593832 9.557255122859765 0.9999999998806929 0.8288102552138455 0.14457372570505855 0.1176349574611976 0.0 0.0 0.106685537704737 0.02587504376233976 7.686829433229116e-11 10.114252755593832 -0.17118974466684733 MDGTYACSYT(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MDGTYACSYTPVK 13 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 1 MDGTYACS(0.052)Y(0.023)T(0.924)PVK 89.911 0.021346 0.0 24384.0 21457.0 21024.0 22034.0 24522.0 19318.0 23428.0 20265.0 19349.0 16598.0 True False 28511.729594047207 23587.109155627157 21525.291893964008 20799.50641519184 19717.0901326499 18304.930072604588 21208.730235968433 19733.065222542347 19631.942520288347 19607.086010304283 1.4541543592486506 1.2029890185227534 1.0978322777108047 1.0608157889581804 1.0056104268777015 0.9335874827592758 1.0816870097281372 1.006425187922971 1.0012677309606843 1.0 14.259087518808975 -3.9082411493597933 0.8024711572389874 1.004976402018392 2.8530380674024993 0.9378476901523156 0.03530902347951683 1.9660661235430503 0.34690445610197246 0.013139898773847357 4.50463357166455 0.00012352613432178 3.9082411493597933 1.8480616653841073 MDGTYACSYT(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 1 MDGTYACSYTPVK 13 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 1 MDGTYACS(0.032)YT(0.968)PVK 84.566 0.032803 0.0 42495.0 43759.0 63298.0 48247.0 54377.0 43531.0 46114.0 35551.0 49868.0 33187.0 True False 41889.013507371434 43657.678724044956 58093.88277734591 51795.24532727385 51178.65176929527 41669.28060571725 48501.557282465095 37202.829245306246 44251.34070667982 38923.328731102134 1.0761929894731623 1.1216327109546462 1.4925209295094366 1.3306992751081503 1.314858041121246 1.070547714291993 1.2460793787071291 0.955797730001928 1.1368847976077718 1.0 15.248347474521992 -7.313058010045134 1.2722575977685353 1.0404261369671524 1.2678634056615576 0.3144358058438248 0.13178298852796524 0.5858581404207894 1.8343048973146612 0.09153144909445046 0.05044286506700539 4.8634223912906454e-08 7.313058010045134 0.22743726869440528 MDGTYACSYTPVK ddPTM_PC-9_Lapatinib_30min_R1 1 MDGTYACSYTPVK 13 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 171.92 0.00099355 3562400.0 15493.0 9609.3 11062.0 13253.0 13482.0 13217.0 12793.0 10412.0 10913.0 9757.8 False True 15272.066978931764 9587.050256243632 10152.525060554854 14227.669830711968 12689.015266631839 12651.73972033183 13455.358943370262 10895.779530874763 9683.863021015415 11444.422728548787 1.33445498660537 0.8377050099982912 0.8871155235491941 1.2431968101999769 1.108751010654154 1.1054939179038992 1.1757132065565068 0.9520602121498535 0.8461643938456108 1.0 13.482357072878699 -7.909528815585422 6.6800242801254806 0.91541925132268 1.08648858054527 0.2154328436411692 0.14441050999595667 0.34051543231560694 20.664567395969183 0.08165770346507344 0.03875021236560416 1.2316042656666896e-08 7.909528815585422 0.17106932922259 MDMT(ph)SPEQSR ddPTM_PC-9_AZD4547_30min_R2 3 MDMTSPEQSR 10 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 MDMT(0.5)S(0.5)PEQSR;MDMT(0.82)S(0.179)PEQS(0.001)R;MDMT(0.833)S(0.167)PEQSR 77.67399999999999 0.01904 13380700.0 59590.0 51493.0 67705.0 97100.0 77722.0 72605.0 55943.0 82058.0 62473.0 70937.0 True False 78538.380451001 68137.10524950233 66807.1874623389 74715.0951800454 66931.64187937543 68064.99787238549 60921.81862404887 69377.82160525162 65775.19523884283 68453.51722154241 1.1473242521172435 0.995377710527042 0.9759496688259955 1.0914719683173923 0.9777677553478867 0.9943243332859066 0.8899735338197743 1.0135026572954287 0.960873858767089 1.0 16.062837050290675 -6.398143491409892 7.113805377432648 0.9694884565916853 1.042838666655711 0.3325603188014137 0.05468207249913503 0.3366609159579645 18.07901982263448 0.016920047668883546 0.019174946493915965 3.9981262937085446e-07 6.398143491409892 0.07335021006402576 MDMT(ph)SPEQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MDMTSPEQSR 10 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 MDMT(0.775)S(0.225)PEQSR;MDMT(0.5)S(0.5)PEQSR 92.538 0.0065428 10425800.0 38327.0 38509.0 42465.0 43460.0 49849.0 40565.0 40855.0 41960.0 35650.0 27345.0 True False 44815.00410724442 42331.91902288516 43477.5266494093 41025.07709922109 40081.44629404065 38437.699989398745 36984.91863541444 40858.59446029493 36171.31380682614 32302.432037099123 1.3873569660567568 1.3104870547910212 1.345952112815396 1.2700305986900327 1.2408182222319168 1.1899320752460159 1.1449577107054203 1.264876725485224 1.119770603194324 1.0 14.979355168486451 -1.5228787463831253 0.06487279374645685 0.6918752520967527 2.4254248112140724 0.8674197796635746 0.040125750616661994 101.1449538763789 0.48940128762108925 2.4676591937707983 16.26719645553685 0.029999999923822126 1.5228787463831253 1.7335495591173196 MDMT(ph)SPEQSR ddPTM_PC-9_Lapatinib_30min_R1 1 MDMTSPEQSR 10 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 MDMT(0.5)S(0.5)PEQSR 80.014 0.0097133 0.0 10987.0 8290.1 9285.4 9941.5 10321.0 8245.2 8039.0 7501.1 11501.0 7103.6 True False 10830.323365230957 8270.904782792222 8521.990254680526 10672.631073871806 9713.939071866725 7892.572016499963 8455.220084870905 7849.6284901118615 10205.63626910092 8331.447795047976 1.2999329326252582 0.9927331943084683 1.0228702698882426 1.281005575071283 1.165936498772815 0.947322987631409 1.0148560361737484 0.9421685982090056 1.2249535159023524 1.0 13.024351505972174 -6.745573077576619 24.84517175767987 1.0215579953424319 1.1435580485770764 0.22699333070897898 0.11612593901738655 371.5596366455706 581827.1921267501 0.038694100287613116 0.03856899781924918 1.7964987626736137e-07 6.745573077576619 0.12200005323464458 MDMTS(ph)PEQSR ddPTM_PC-9_AZD4547_30min_R2 1 MDMTSPEQSR 10 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 MDMT(0.182)S(0.818)PEQSR 105.17 0.0014942 6892100.0 13643.0 10868.0 18241.0 21210.0 19248.0 16606.0 12828.0 18540.0 15312.0 16486.0 True False 17981.190207971256 14380.868464676598 17999.112421542326 16320.362191233397 16575.747444664514 15567.62419487408 13969.667148871156 15675.06900681666 16121.361059932444 15908.830157947861 1.1302647667646428 0.9039551193833123 1.1313913243677558 1.0258681517873858 1.0419212022565636 0.978552416507928 0.8781077558925399 0.9853062010964762 1.0133593042275584 1.0 13.957540131787962 -6.805769677157831 4.75639034454884 0.9630608321712028 1.0426068101885428 0.23137343152555656 0.06836601520743876 0.2988628073496481 14.847483231181135 0.023553336891919026 0.02124384533658365 1.5639768590093028e-07 6.805769677157831 0.07954597801734009 MDMTS(ph)PEQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MDMTSPEQSR 10 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 MDMT(0.194)S(0.806)PEQSR;MDMT(0.417)S(0.546)PEQS(0.038)R 89.266 0.005654 11685400.0 53785.0 49935.0 52926.0 56254.0 58556.0 51367.0 56536.0 50223.0 45923.0 40019.0 True False 62889.738197827675 54892.216791081846 54187.956562972744 53102.270757928694 47082.372147763155 48673.22409356455 51180.500794805834 48904.69946566713 46594.536997219584 47274.127909770315 1.330320430614015 1.1611471055764748 1.1462497344509135 1.123283984408602 0.9959437482935031 1.029595388548777 1.0826323627268473 1.0344918378824248 0.9856244643190916 1.0 15.528763223830156 -1.5228787540462438 0.43314770001211933 1.0135996323094163 7.264579941875269 0.8828593189603462 0.03451571608401144 27.189788915659136 0.3395658085909864 0.023585374858608236 148.64609025647965 0.029999999394472652 1.5228787540462438 6.250980309565852 MDMTS(ph)PEQSR ddPTM_PC-9_Lapatinib_30min_R1 1 MDMTSPEQSR 10 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 MDMT(0.103)S(0.897)PEQSR 68.069 0.025075999999999998 1114100.0 10661.0 10833.0 13770.0 11859.0 10647.0 12241.0 9006.4 9598.1 12992.0 8172.1 True False 10508.972185012039 10807.916854077537 12637.883753737144 12731.1504204643 10020.764392807385 11717.480965164705 9472.707323346356 10044.062765586734 11528.704148174864 9584.636596361219 1.096439294214007 1.1276292789421702 1.318556382047399 1.328287232642461 1.0455027994083512 1.2225274111710416 0.9883220118061277 1.0479336033877316 1.2028316391830343 1.0 13.226508017487543 -6.778788101108117 1.6478930596250108 1.0724508207533068 1.2085488204554815 0.24057337405693457 0.10315104023471125 0.5611853315028366 3.157685872796261 0.046325115529079974 0.0415991994184561 1.6642244527647847e-07 6.778788101108117 0.13609799970217473 MDPASTLGLS(ph)TES(ph)IHGY(ph)S(ph)IS(ph)HVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MDPASTLGLSTESIHGYSISHVK 23 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-5 Q8NEY1-2 NAV1 Neuron navigator 1 5 MDPAS(0.004)T(0.005)LGLS(0.888)T(0.517)ES(0.889)IHGY(0.928)S(0.936)IS(0.832)HVK 45.347 0.017431 3255100.0 5182.9 5137.7 6166.8 5464.4 8037.0 7827.7 5106.6 5877.2 5435.0 4589.8 True False 6060.262603058861 5647.736902123583 6313.8398997192335 5158.2473838238275 6462.207544087238 7417.201632121698 4622.865879417637 5722.929727408137 5514.476592990188 5421.89440716319 1.1177389576330155 1.0416537981009033 1.164508089898918 0.9513736337264254 1.1918726295277213 1.368009237199896 0.8526292716638102 1.0555221658037515 1.017075615804078 1.0 12.40458130124136 -7.29367314463831 24.999925676313502 0.9859336550713559 1.1297672819359206 0.3208345569937291 0.11195381425878775 944.2760816393836 732359.857626971 0.04828168201826214 0.03255483289031199 5.08542033552234e-08 7.29367314463831 0.1438336268645647 MDPHAVEIS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 MDPHAVEISR 10 0 P41970;F8VUJ0 P41970 ELK3 ETS domain-containing protein Elk-3 1 MDPHAVEIS(1)R;MDPHAVEIS(1)R 86.189 0.011425 5044200.0 2875.33 1912.21 39173.0 66812.0 47134.0 26181.0 11742.7 58778.0 19395.2 22000.2 True False 3789.6251294206522 2530.294487195367 38653.54042481651 51409.525635110185 40590.25769206243 24543.897931229574 12787.777551375837 49695.21068407066 20420.390675914434 21229.97969433971 0.1785034740485896 0.11918496972797334 1.8207054825927238 2.421553217444522 1.9119310652418813 1.1560961566898444 0.6023452558829007 2.34080349579045 0.961865765767024 1.0 14.373815370910997 -5.256051083350391 24.710872563124028 1.574236815478831 0.14884399570582957 0.47742363917570796 0.5750021190336322 314.4226116228638 1441936.7779572844 0.15247853325675623 0.3792380127117351 5.545604796321141e-06 5.256051083350391 -1.4253928197730015 MDRT(ph)PPPPT(ph)LSPAAITVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MDRTPPPPTLSPAAITVGR 19 1 Q8NDX5-2;Q8NDX5;Q8NDX5-7;E7EX82;H7C4H9 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 2 MDRT(1)PPPPT(0.996)LS(0.004)PAAITVGR;MDRT(1)PPPPT(0.855)LS(0.144)PAAIT(0.001)VGR 86.08 0.0009887000000000001 12248800.0 64406.0 65386.0 79483.0 82497.0 99345.0 84794.0 87225.0 79387.0 76794.0 63988.0 True False 75308.66372351561 71877.08995898024 81378.1761609561 77874.96054888247 79879.06040404944 80347.25336869422 78962.41654568643 77303.17536747924 77916.96697002537 75588.51787127057 0.9962976632478552 0.9508995808250799 1.0765944147700515 1.0302485449113552 1.0567618290926908 1.0629557984656866 1.0446350685187624 1.0226840999730777 1.030804269806166 1.0 16.20587948081767 -5.255658475993652 24.95525136234002 1.0425477651261823 0.9735986193973903 0.5739506750500531 0.023036084504944442 294.5255360960224 1271409.8627542483 0.005671607167497574 0.01419649279588287 5.550620355476815e-06 5.255658475993652 -0.06894914572879196 MDRT(ph)PPPPTLS(ph)PAAITVGR ddPTM_PC-9_AZD4547_30min_R2 3 MDRTPPPPTLSPAAITVGR 19 1 Q8NDX5-2;Q8NDX5;Q8NDX5-7;E7EX82;H7C4H9 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 2 MDRT(1)PPPPT(0.075)LS(0.913)PAAIT(0.013)VGR;MDRT(1)PPPPT(0.082)LS(0.918)PAAITVGR;MDRT(1)PPPPT(0.461)LS(0.538)PAAIT(0.001)VGR 136.26 7.7134e-05 23927600.0 67479.0 65253.0 114983.0 155796.0 117826.0 105384.0 91197.0 129279.0 94758.0 104182.0 True False 88935.91834960725 86344.75615803666 113458.25029144243 119879.63922420543 101467.893724805 98794.32182058338 99313.35632800146 109301.90108588201 99766.71442770903 100534.61989053291 0.8846297767519796 0.8588559468574419 1.1285490551909523 1.192421469885064 1.0092831089955707 0.9826895643327199 0.9878523083504844 1.0872065881871873 0.992361780810829 1.0 16.617332864833656 -5.247861572438509 24.715037920433648 1.0500194521577038 0.8717428235143324 0.528665791800045 0.06636575866265103 557.7176368612226 1015181.7751482757 0.01842086824091625 0.04813766554664837 5.651170722246321e-06 5.247861572438509 -0.17827662864337135 MDRT(ph)PPPPTLS(ph)PAAITVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MDRTPPPPTLSPAAITVGR 19 1 Q8NDX5-2;Q8NDX5;Q8NDX5-7;E7EX82;H7C4H9 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 2 MDRT(1)PPPPT(0.035)LS(0.939)PAAIT(0.026)VGR 76.133 0.0030789999999999997 8444700.0 13624.0 17343.0 16976.0 19737.0 22357.0 21490.0 18005.0 19918.0 16359.0 13874.0 True False 15930.27411373439 19064.698424105976 17380.772221838524 18631.199878217343 17976.306341067353 20363.026569017118 16299.436055088423 19395.173604865464 16598.219426812586 16389.24637347642 0.9719955238158595 1.163244360946296 1.060498562640851 1.1367941791618432 1.0968354451098712 1.242462655389187 0.9945201678990352 1.1834085084140107 1.0127506200452485 1.0 14.00046189608289 -8.403084895160948 7.6553249865783215 1.0004999789641404 1.1080192333179704 0.20658532823863185 0.0783697187809303 0.37992379434349355 21.112842644753513 0.06943730292431184 0.0179553655941603 3.9528934201402116e-09 8.403084895160948 0.10751925435382992 MDRT(ph)PPPPTLS(ph)PAAITVGR ddPTM_PC-9_Lapatinib_30min_R1 5 MDRTPPPPTLSPAAITVGR 19 1 Q8NDX5-2;Q8NDX5;Q8NDX5-7;E7EX82;H7C4H9 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 2 MDRT(1)PPPPT(0.027)LS(0.85)PAAIT(0.124)VGR;MDRT(1)PPPPT(0.008)LS(0.99)PAAIT(0.002)VGR;MDRT(1)PPPPT(0.184)LS(0.728)PAAIT(0.088)VGR;MDRT(1)PPPPT(0.072)LS(0.833)PAAIT(0.096)VGR;MDRT(1)PPPPT(0.06)LS(0.937)PAAIT(0.002)VGR 93.104 0.00067579 18795700.0 104310.0 85854.0 114676.0 95049.7 96814.0 112740.0 84965.0 90838.3 123724.0 76360.5 True False 102822.52027188896 85655.21033785418 105247.78194216116 102039.9720145044 91119.59086364749 107918.37300977611 89364.07196306218 95058.97903951805 109788.9002485211 89559.3106810295 1.1480941455444775 0.9564076552902468 1.1751740957119137 1.1393563800186612 1.0174217529227645 1.2049933411628573 0.9978200064685326 1.0614081139824303 1.2258792459841548 1.0 16.450555803665736 -5.279057727408247 24.99287922425835 1.1031127933231715 1.0522508609930745 0.04788474557279698 0.09007252234367497 2419.1260192187538 3431698.3156432323 0.02244640060355953 0.04690606239017832 5.2594735162848016e-06 5.279057727408247 -0.05086193233009695 MDRT(ph)PPPPTLSPAAIT(ph)VGR ddPTM_PC-9_Lapatinib_30min_R1 1 MDRTPPPPTLSPAAITVGR 19 1 Q8NDX5-2;Q8NDX5;Q8NDX5-7;E7EX82;H7C4H9 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 2 MDRT(1)PPPPT(0.089)LS(0.397)PAAIT(0.514)VGR 81.839 0.0033399000000000002 1994600.0 7809.9 6862.6 8715.4 7961.4 8140.4 9492.7 8771.9 8568.3 9012.5 4636.0 True False 7698.529393839751 6846.710071336888 7998.853454416896 8546.907914451842 7661.5976766421745 9086.7193495645 9226.066060763666 8966.414498117005 7997.4173441676385 5437.326422918299 1.4158666953285157 1.2592052672206777 1.4711004696539416 1.5718953120832833 1.4090744385602059 1.6711741475119155 1.6968019469781788 1.6490484110579826 1.4708363489928749 1.0 12.408681725744465 -5.458890422034719 5.106146427033619 1.5341177785671805 1.339679982570112 0.06989613243770232 0.19423104353737536 0.3963828895864085 20.39909048570776 0.04901445451842316 0.10299000399763211 3.4762386025529316e-06 5.458890422034719 -0.19443779599706845 MDRT(ph)PPPPTLSPAAITVGR ddPTM_PC-9_AZD4547_30min_R2 4 MDRTPPPPTLSPAAITVGR 19 1 Q8NDX5-2;Q8NDX5;Q8NDX5-7;E7EX82;H7C4H9 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 1 MDRT(1)PPPPTLSPAAITVGR;MDRT(1)PPPPTLSPAAITVGR;MDRT(1)PPPPTLSPAAITVGR;MDRT(1)PPPPTLSPAAITVGR 145.82 0.00044478 26112900.0 46148.6 52386.6 74565.9 93433.0 84940.0 67294.8 60290.899999999994 79293.2 56645.299999999996 66488.0 True False 60822.894849489276 69319.54397420188 73577.10744550651 71893.4653754602 73147.5471711244 63086.845517837624 65656.67330105056 67040.25791646788 59639.45491432808 64160.27535737217 0.9479836941270324 1.0804121956785975 1.1467704437938064 1.1205292523296422 1.1400753310937837 0.9832695568471994 1.0233228104982945 1.0448873160698613 0.9295386371417024 1.0 15.96939271298603 -6.773606431151404 24.989009716378295 1.0007040533302667 1.0919458158860946 0.37009293161320267 0.05901700963819926 262.8083524189558 539759.6295730496 0.02155249046847247 0.01914736920048699 1.6841996348094676e-07 6.773606431151404 0.09124176255582794 MDRT(ph)PPPPTLSPAAITVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 MDRTPPPPTLSPAAITVGR 19 1 Q8NDX5-2;Q8NDX5;Q8NDX5-7;E7EX82;H7C4H9 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 1 MDRT(1)PPPPTLSPAAITVGR;MDRT(1)PPPPTLSPAAITVGR;MDRT(1)PPPPTLSPAAITVGR 69.98 0.0047547 51459900.0 85422.0 80340.0 78164.0 108883.0 113223.0 100021.0 105759.0 91623.0 91203.0 78415.0 True False 99882.25743859491 88315.62425143733 80027.72619862088 102782.63851344884 91037.7659281064 94775.72268309261 95740.74189114646 89217.99333259305 92536.67133587562 92631.01876720166 1.0782808908710906 0.9534130729296015 0.8639409051491151 1.1095920122800336 0.9828000073809035 1.0231531936540714 1.0335710776512141 0.9631546162394461 0.9989814704341842 1.0 16.499207760163472 -5.764587436363979 24.9994879330141 1.0140181499687175 0.9640317874851415 0.12734033684504864 0.06063681380053772 175.39781204012732 1392894.9866028973 0.016918245436016676 0.026351336864965276 1.7195411117446472e-06 5.764587436363979 -0.04998636248357602 MDRT(ph)PPPPTLSPAAITVGR ddPTM_PC-9_Lapatinib_30min_R1 3 MDRTPPPPTLSPAAITVGR 19 1 Q8NDX5-2;Q8NDX5;Q8NDX5-7;E7EX82;H7C4H9 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 1 MDRT(1)PPPPTLSPAAITVGR;MDRT(1)PPPPTLSPAAITVGR;MDRT(1)PPPPTLSPAAITVGR 116.09 0.0015475 60519900.0 147085.0 100701.0 131261.0 121089.0 102019.0 97361.0 104727.0 105715.4 129574.0 99860.0 True False 144987.54092791435 100467.83302155107 120469.2272621126 129994.28900106225 96018.44299707114 93197.096989576 110149.25162685354 110627.32341704154 114980.01164529021 117120.66794491398 1.2379330093652399 0.8578147203600706 1.0285906781096363 1.1099175857006143 0.8198249265640462 0.7957357025440627 0.9404766345651363 0.9445585084015531 0.9817226426626035 1.0 16.837636160955448 -4.751621119574784 24.989165459037373 0.9398446328737199 1.2379336122929858 0.4835393373234179 0.09170429455803804 376.63128748303825 958524.7820937167 0.024360236983066202 0.31604814382601965 1.7716538829965714e-05 4.751621119574784 0.29808897941926593 MDS(ph)FDEDLAR ddPTM_PC-9_AZD4547_30min_R2 1 MDSFDEDLAR 10 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 MDS(1)FDEDLAR 92.866 0.0063041 1832000.0 28829.0 37016.0 34296.0 41186.0 35625.0 44344.0 32748.0 43626.0 40065.0 35698.0 True False 37996.022319548734 48980.69811266741 33841.212631391674 31691.204017356868 30679.08368226174 41571.162669968464 35662.50855871785 36884.60412574886 42182.75410568139 34448.22388562554 1.1029892991203998 1.4218642527200345 0.9823790260929197 0.9199662694534705 0.8905853545344443 1.2067723087260578 1.0352495582101404 1.0707258594292859 1.224526241054863 1.0 15.072141980549958 -5.2786785831144645 24.94696711964379 1.0397826091148625 1.2624267982228659 0.33496223956238946 0.12463067543201874 783.0722014722209 1133188.2893931374 0.033114234635439034 0.06918249869993268 5.2640671046098335e-06 5.2786785831144645 0.22264418910800332 MDS(ph)FDEDLARPSGLLAQER ddPTM_PC-9_Lapatinib_30min_R1 2 MDSFDEDLARPSGLLAQER 19 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 MDS(1)FDEDLARPSGLLAQER;MDS(1)FDEDLARPSGLLAQER 88.98299999999999 0.00051137 5652700.0 2766.6000000000004 3509.7999999999997 6950.0 3662.44 3739.6 5459.9 3125.0 6125.3 6040.400000000001 6332.200000000001 True False 2727.147776667698 3501.6732737414695 6378.597827775826 3931.7880551416874 3519.644080336479 5226.392804648542 3286.797209257568 6409.903799507025 5360.066543768119 7426.712332873864 0.3672079453779506 0.47149709276358237 0.8588723437612324 0.5294116533553993 0.4739168453794825 0.7037289947954831 0.44256422787627997 0.8630876641248104 0.7217280410932478 1.0 12.858507982539646 -14.522878745280336 0.08736435810047187 2.38052887348845 0.24586645375479838 0.4813222971769311 0.1475102919282228 205.48652913536378 1.249152519532981 52.335765567247165 3.9318092884495903 3.0000000000000132e-15 14.522878745280336 -2.1346624197336515 MDSNFGLAGLPGS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 MDSNFGLAGLPGSPK 15 0 O43463;O43463-2 O43463 SUV39H1 Histone-lysine N-methyltransferase SUV39H1 1 MDSNFGLAGLPGS(1)PK 98.227 0.0022971 7996200.0 39158.0 32632.0 30506.0 39462.0 40387.0 32390.0 39869.0 35463.0 32078.0 34559.0 True False 51609.42946300214 43179.65584645999 30101.470507733695 30364.645581822373 34779.96218036504 30364.64817969237 43417.263763512936 29983.008208669868 33773.577591465044 33349.099928940916 1.5475508956154647 1.2947772485154223 0.9026171792304094 0.9105086987811452 1.0429055732980186 0.9105087766803989 1.3019021159798887 0.8990649904362218 1.0127283094125057 1.0 15.025360204060465 -5.011505826641126 3.2204261085033363 1.0011486853952294 1.5341653511526414 0.7043847495461313 0.11506538827884205 0.13544936449793088 2.761393501994927 0.029999601760470826 0.13701851850119987 9.7385471967788e-06 5.011505826641126 0.533016665757412 MDSNFGLAGLPGS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 MDSNFGLAGLPGSPK 15 0 O43463;O43463-2 O43463 SUV39H1 Histone-lysine N-methyltransferase SUV39H1 1 MDSNFGLAGLPGS(1)PK;MDSNFGLAGLPGS(1)PK;MDS(0.003)NFGLAGLPGS(0.997)PK;MDS(0.002)NFGLAGLPGS(0.998)PK 111.11 0.00040234 30719200.0 153211.0 149170.0 117296.0 171580.0 176063.0 155893.0 175757.0 181600.0 155400.0 134070.0 True False 179146.59624481524 163978.6117698139 120092.78148755743 161966.92886986537 141564.71902882063 147717.69664605806 159108.024589513 176833.19242110525 157672.43101208404 158375.82970246434 1.1311485886537882 1.0353764970189916 0.7582772050076829 1.0226745405163624 0.8938530538073505 0.9327035376772492 1.0046231479160943 1.1165415376406627 0.9955586739990455 1.0 17.27299265184233 -7.520311587146233 24.582964825223804 1.0457465376582162 0.9570670042803399 0.10556141387497486 0.0971964964416149 173.27620799319524 1659349.685576938 0.045731166740125374 0.02700671207395379 3.017785815231529e-08 7.520311587146233 -0.08867953337787637 MDSNFGLAGLPGS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 MDSNFGLAGLPGSPK 15 0 O43463;O43463-2 O43463 SUV39H1 Histone-lysine N-methyltransferase SUV39H1 1 MDS(0.001)NFGLAGLPGS(0.999)PK;MDSNFGLAGLPGS(1)PK;MDSNFGLAGLPGS(1)PK 137.52 7.551799999999999e-06 16331500.0 185501.0 152857.0 133356.0 165160.0 165991.0 140897.0 128135.0 126373.0 140007.0 133468.0 True False 182855.72172328297 152503.06900800584 122391.98444904655 177306.41735760868 156227.73573086222 134871.16375694884 134769.20333062994 132244.75092731824 124237.9373209297 156537.76596506865 1.1681252801581898 0.9742254085958838 0.7818687311300857 1.1326750210372527 0.998019454076816 0.8615886583372174 0.8609373111962236 0.8448105165677949 0.7936611114576233 1.0 17.256151235093434 -6.756890272876998 7.679697297105793 0.8615712194202971 1.0032369860861234 0.28640374065649876 0.10856155665210933 0.17299079734504746 68.60652869089903 0.037365352421105315 0.03540523554101626 1.750288853811126e-07 6.756890272876998 0.1416657666658263 MDTMMLNVRNLFEQLVR ddPTM_PC-9_Lapatinib_30min_R1 1 MDTMMLNVRNLFEQLVR 17 1 Q9H0H5;F8VRD2;F8VVY0;F8VXH1;F8VUW9;F8VV39;F8VS54;F8VWX0;F8W0L1;F8VZ66;F8VV47;F8VWY4;F8VVE5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 0 58.511 0.024636 1059200.0 14053.0 8555.5 6844.1 8119.7 6183.2 5903.9 7358.7 5019.9 5672.7 4555.0 False True 13852.601642995425 8535.690265398356 6281.404516990004 8716.849824525167 5819.516332638922 5651.403959663093 7739.697479604371 5253.142880045932 5033.780789820778 5342.325680844014 2.5929908565227917 1.5977480174982208 1.1757809037201246 1.6316582599561815 1.0893226434146408 1.0578546306016763 1.4487505895338089 0.9833063713959138 0.942245211270143 1.0 12.383252213427406 -1.9419697731227563 0.8287802058857665 1.1346156040594197 199.99999999967284 0.8256693872344923 0.20034143872263374 107.51010883082132 0.7217928391610771 0.0711160073809732 39712.01026512074 0.011429578818408746 1.9419697731227563 198.8653843956134 up MDTSRLGVLLSLPVLLQLATGGS(ph)S(ph)PRSGVLLR ddPTM_PC-9_AZD4547_30min_R2 1 MDTSRLGVLLSLPVLLQLATGGSSPRSGVLLR 32 2 O75473-3;O75473-2;O75473 O75473-3 LGR5 Leucine-rich repeat-containing G-protein coupled receptor 5 2 MDTSRLGVLLSLPVLLQLAT(0.175)GGS(0.625)S(0.625)PRS(0.574)GVLLR 48.422 0.011313 1496400.0 770.98 651.32 2040.8 4382.9 2544.7 1009.1 1066.2 870.87 1058.0 860.39 True False 1016.1356026197809 861.846452743206 2013.7376585649674 3372.4901201299795 2191.4123297193382 946.0008174784679 1161.0897344969148 736.2970521017489 1113.9237200501916 830.2680079823343 1.2238645748727937 1.038034037753197 2.4254067833573734 4.061929506745171 2.6394035524080617 1.139392109997566 1.3984517328549404 0.8868185272982543 1.34164355285371 1.0 9.697433298975232 -6.770770379666259 24.846269553810032 1.1615114602760686 2.316182533251853 0.3378032822524468 0.7862236747283177 248.9815083177331 662975.289169589 0.3152601322743933 0.28178320272036916 1.6952338681986976e-07 6.770770379666259 1.1546710729757843 MDYEDDRLR ddPTM_PC-9_AZD4547_30min_R2 2 MDYEDDRLR 9 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 0 ; 91.069 0.010482 9753100.0 42362.0 37435.0 115211.0 170865.0 112750.0 80705.0 48848.0 158408.0 58281.0 69606.0 False True 55832.23481566208 49535.131668675815 113683.22686246989 131474.7140879346 97096.60870666699 75658.50359191326 53195.377368885056 133929.68345371194 61361.61467698031 67169.11512641743 0.8312188527507253 0.7374688735358044 1.692492548822615 1.9573685590540997 1.4455543820091081 1.1263882730853036 0.7919618602800896 1.9939176391060982 0.9135391252585812 1.0 16.035510402786883 -10.221918308100786 14.768644356501367 0.9999999991275234 1.3004377199294233 0.029997756112340235 0.45418829353510715 0.0 0.0 0.45678712909750147 0.11078715186421467 5.999039090977691e-11 10.221918308100786 0.3004377208018999 MDYEDDRLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MDYEDDRLR 9 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 0 84.743 0.010676 0.0 15525.0 15407.0 17773.0 24213.0 22084.0 20501.0 20220.0 22335.0 18567.0 17039.0 False True 18153.07586727292 16936.505138684242 18196.775724477844 22856.42410960516 17756.798731320458 19425.891470052127 18304.61521987713 21748.729915888638 18838.50724968698 20128.035819350207 0.9018801451963511 0.8414385432682027 0.9040512391668275 1.1355516412402247 0.8821923257037259 0.9651161019584897 0.9094089152146619 1.0805192374995858 0.9359337105102162 1.0 14.296918774265663 -5.5388776553388395 24.999972587123263 0.9847309774445692 0.8719306674792144 0.3083410438628975 0.07275689112151001 260.31627879812027 406769.92819265544 0.01911451319777846 0.03311919600080964 2.8914943275970964e-06 5.5388776553388395 -0.11280030996535473 MDYEDDRLR ddPTM_PC-9_Lapatinib_30min_R1 2 MDYEDDRLR 9 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 0 ; 115.7 0.0025447 20780600.0 104164.0 95758.0 173068.0 117403.0 142257.0 200315.0 91951.0 127814.0 179208.0 94518.0 False True 102678.60225866186 95536.27823435415 158839.0171017992 126037.20826492702 133889.72294802286 191747.99440707205 96711.77286030164 133752.70504794738 159023.7078960991 110855.31036268169 0.9262398158710814 0.8618105702089619 1.4328498705396322 1.1369523737976577 1.2077880843955986 1.7297141091368236 0.8724144341294333 1.206552077752099 1.4345159232861868 1.0 16.758318356508546 -5.246802640831522 24.648088069487216 1.2577064890480982 0.8940251112159548 0.2827349820591306 0.2283322920771024 831.7682334219127 1400680.2825885948 0.05668035585465737 0.1484844812943732 5.6649666719051495e-06 5.246802640831522 -0.3636813778321434 MEAQS(ph)HS(ph)S(ph)T(ph)TTEKK ddPTM_PC-9_Lapatinib_30min_R1 1 MEAQSHSSTTTEKK 14 1 F8WEV4;C9J9N4;P10071 F8WEV4 GLI3 Transcriptional activator GLI3;Transcriptional repressor GLI3R 4 MEAQS(1)HS(0.991)S(0.902)T(0.397)T(0.369)T(0.341)EKK 50.387 0.044895 0.0 3836.5 5812.7 7006.0 5217.3 6034.3 5851.0 4890.5 5413.3 7033.9 4798.9 True False 3781.790806472064 5799.241050281221 6429.993723942077 5600.997646402597 5679.374337890261 5600.766369347167 5143.70616059972 5664.821680223238 6241.668111749317 5628.383470867692 0.6719142052147788 1.0303564212171898 1.1424228212635992 0.9951343357099168 1.009059593626926 0.9950932445055547 0.9138869423562477 1.0064740097301736 1.1089628388072639 1.0 12.45850490973128 -4.760489461119474 24.99970849152448 1.020820069570224 0.6719137953614108 0.7533674356088762 0.0601508433097562 12.247416386138978 322156.71337942075 0.015874630538299468 0.09380784412281297 1.7358433854975724e-05 4.760489461119474 -0.34890627420881326 MEDEGGFPVPQENGQPES(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 MEDEGGFPVPQENGQPESPR 20 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 MEDEGGFPVPQENGQPES(1)PR;MEDEGGFPVPQENGQPES(1)PR;MEDEGGFPVPQENGQPES(1)PR;MEDEGGFPVPQENGQPES(1)PR 146.89 1.8113e-14 29789000.0 50469.3 52793.3 68881.8 83482.3 83056.5 72954.40000000001 65186.0 81641.2 69764.8 71816.8 True False 66517.48757334633 69857.70179575011 67968.38232543148 64236.745523677666 71525.5386345478 68392.54983515127 70987.42771798527 69025.42846814018 73452.42490033797 69302.51569133255 0.9598134628995216 1.0080110526851624 0.9807491351130284 0.9269035168908242 1.0320770887036252 0.9868696562151626 1.0243124222814244 0.9960017725124656 1.0598810759985793 1.0 16.08062010290091 -6.289821105109795 24.998432415080554 1.0152304957504077 0.9725136759608576 0.4234278323161136 0.027084097458071346 777.2349816001677 684581.0221764898 0.008263827083315172 0.009372468222563053 5.130726857322491e-07 6.289821105109795 -0.04271681978955011 MEDEGGFPVPQENGQPES(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MEDEGGFPVPQENGQPESPR 20 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 MEDEGGFPVPQENGQPES(1)PR;MEDEGGFPVPQENGQPES(1)PR 207.38 2.9162e-21 23556000.0 45364.0 53668.0 61366.0 54630.0 76145.0 69231.0 72614.0 59121.0 56279.0 45504.0 True False 53043.22922015904 58995.804360544294 62829.19817185098 51569.25821284969 61224.9338614561 65600.40448578993 65735.47624016622 57569.13639387742 57101.97390559239 53753.514990534226 0.9867862451320576 1.0975245873862056 1.1688388784047878 0.9593653219130102 1.138994052244538 1.2203928337959273 1.2229056323431493 1.0709836631895628 1.0622928363967978 1.0 15.714071476458214 -4.773624170842378 4.530379377807183 1.113491630720859 0.9777739041574013 0.14969852994044963 0.08258375014891804 0.3596727010816259 16.411333377958357 0.021461587634742308 0.15599428925475609 1.6841308414627536e-05 4.773624170842378 -0.13571772656345782 MEDEGGFPVPQENGQPES(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 MEDEGGFPVPQENGQPESPR 20 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 MEDEGGFPVPQENGQPES(1)PR;MEDEGGFPVPQENGQPES(1)PR;MEDEGGFPVPQENGQPES(1)PR;MEDEGGFPVPQENGQPES(1)PR 211.11 1.0799e-21 24053900.0 73789.4 70414.7 79350.9 63143.6 81138.2 76529.5 70777.6 70526.9 92753.6 63788.8 True False 72737.14962468127 70251.65908841635 72826.97530533191 67787.39098487473 76365.81059983875 73256.51168397782 74442.11781054352 73803.83724510658 82306.71282929121 74814.60908676666 0.9722319011294165 0.9390099065670662 0.9734325447169071 0.9060715789647169 1.020733938625183 0.9791738883380139 0.9950211425178852 0.9864896461533624 1.100142256091127 1.0 16.191032392965717 -7.228679252735231 0.805793164288775 1.0360884100332957 0.9522670269159711 0.4043537953291696 0.03740400309828342 0.6396232974772486 0.8185736273208939 0.029042495017561627 0.01802184361223504 5.906371329258541e-08 7.228679252735231 -0.08382138311732457 MEDEGGFPVPQENGQPES(ph)PRR ddPTM_PC-9_Lapatinib_30min_R1 2 MEDEGGFPVPQENGQPESPRR 21 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 MEDEGGFPVPQENGQPES(1)PRR;MEDEGGFPVPQENGQPES(1)PRR 108.94 2.294e-05 5277500.0 16935.5 15712.4 18807.4 16072.1 18355.3 20918.7 17252.7 15658.2 19213.6 13525.099999999999 True False 16693.99666440967 15676.018903166985 17261.128170663458 17254.095848953886 17275.677341908275 20024.05596487141 18145.96038789057 16385.737135069452 17049.56203982238 15862.895513937072 1.0523927772040356 0.9882192623278708 1.088144857002803 1.0877015380826605 1.089062039570893 1.262320359311348 1.143924851042964 1.0329600368780727 1.0748076872121302 1.0 13.953368515176557 -5.419226324208739 4.379049399710655 1.1072448787412008 1.0208618494725419 0.16269255974163732 0.06806009990967583 0.3715861168811101 11.808298034964533 0.019170737629734914 0.04164899794837122 3.8086729001114166e-06 5.419226324208739 -0.08638302926865893 MEEASEGGGNDR ddPTM_PC-9_AZD4547_30min_R2 2 MEEASEGGGNDR 12 0 Q9BV40;B8ZZT4 Q9BV40 VAMP8 Vesicle-associated membrane protein 8 0 ; 60.49 0.040546 7029700.0 566.98 625.45 3151.1 3710.9 2587.5 2288.8 949.08 2180.4 1098.1 1233.3 False True 747.2678460833795 827.6144811586295 3109.314355107837 2855.4093378334746 2228.270288501114 2145.680974179681 1033.546281388418 1843.4692806075018 1156.1433241844181 1190.1225423873038 0.6278915149228345 0.6954027435683151 2.612600168778222 2.399256577482954 1.8723032369686547 1.802907597965158 0.8684368580358082 1.548974340835213 0.9714489752166817 1.0 10.216894414659496 -7.249291882150028 23.695719292856506 1.1429628994395338 1.709574959147223 0.16693044814181257 0.6176533479408949 790.805513448387 1542599.9476012865 0.26361507556027236 0.20238322242423656 5.632589715324881e-08 7.249291882150028 0.5666120597076891 MEEASEGGGNDR ddPTM_PC-9_Lapatinib_30min_R1 1 MEEASEGGGNDR 12 0 Q9BV40;B8ZZT4 Q9BV40 VAMP8 Vesicle-associated membrane protein 8 0 69.721 0.021356 2775900.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 False True 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MEEELPLFSGDS(ph)GK ddPTM_PC-9_AZD4547_30min_R2 1 MEEELPLFSGDSGK 14 0 O95199 O95199 RCBTB2 RCC1 and BTB domain-containing protein 2 1 MEEELPLFS(0.003)GDS(0.997)GK 67.115 0.030876 12368000.0 582.16 2121.6 6175.1 3967.5 5911.5 3999.3 2180.2 5788.8 3321.3 2632.9 True False 767.2747703197638 2807.365709850745 6093.214139261334 3052.8541722639557 5090.790264917618 3749.22313877875 2374.233576392958 4894.273973390525 3496.857137431663 2540.7229723923897 0.3019907241588343 1.1049475839576794 2.3982205873959788 1.201569083066673 2.0036778193586526 1.475652079946526 0.934471645351141 1.9263312161821364 1.3763236588280856 1.0 11.311023364443871 -4.8853802415534595 3.9359078052398764 1.563785955040279 0.3030435154263641 0.4216990808381875 0.43983900767137957 0.20152925426402718 5.256905469490059 0.1055387239446472 0.5814062152574031 1.3020263050602414e-05 4.8853802415534595 -1.260742439613915 MEEEQHHWDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MEEEQHHWDDR 11 0 Q96KR1 Q96KR1 ZFR Zinc finger RNA-binding protein 0 ; 79.23 0.009762100000000001 12620600.0 21946.8 27711.0 34911.0 21489.8 26705.0 27400.0 21646.0 20935.0 21443.2 17360.1 False True 25661.959770941423 30461.96494438106 35743.410640704795 20285.796176871627 21472.34695344651 25963.095765056714 19595.53417653118 20385.47843246603 21756.766233451188 20507.348707524015 1.2513543382390633 1.4854170267853668 1.7429562031873367 0.9891964322735146 1.047056216758456 1.2660386349958062 0.9555371811345706 0.994057238856368 1.0609253562586942 1.0 14.323853364602009 -5.77736079923201 24.9999875046311 1.0500466979250092 1.4924599960726515 0.6942581799164835 0.13637603680868815 130.00515323381762 204135.17354684434 0.039310975087522286 0.058519794769867454 1.6697028973188957e-06 5.77736079923201 0.4424132981476423 MEEESQS(ph)QGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MEEESQSQGR 10 0 Q14683;G8JLG1 Q14683 SMC1A Structural maintenance of chromosomes protein 1A;Structural maintenance of chromosomes protein 1 MEEES(0.001)QS(0.999)QGR 96.82 0.013624 0.0 14530.0 22474.0 21578.0 15307.0 20495.0 14170.0 17549.0 12416.0 13425.0 14084.0 True False 16989.642019418716 24705.070194508324 22092.501355020704 14449.398415963567 16479.15187458852 13426.900255140654 15886.63167624252 12090.09315583941 13621.315227395266 16637.317711117354 1.021176749426738 1.4849190610815801 1.3278884095756673 0.8684932671754065 0.9904933091213889 0.8070351536394932 0.9548793833291281 0.7266852365126497 0.8187206293652287 1.0 14.02213523870193 -5.763373344545477 24.999912859176238 0.8740838740755988 1.2986872384544932 0.649535487089262 0.13334139500241468 27.73916553066645 358585.85429741425 0.03607753974055238 0.05670238278956585 1.7243548998799691e-06 5.763373344545477 0.42460336437889434 MEES(ph)DEEAVQAK ddPTM_PC-9_Lapatinib_30min_R1 1 MEESDEEAVQAK 12 0 I3VM54;Q9Y2K7;Q9Y2K7-3;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 1 MEES(1)DEEAVQAK 172.33 0.0011470999999999999 4316200.0 31031.0 34490.0 45151.0 42311.0 37944.0 42439.0 37733.0 39419.0 50380.0 34197.0 True False 30588.492249611558 34410.14052405927 41438.85906790019 45422.69208535838 35712.20852077422 40623.98290014094 39686.630111013044 41250.550646134485 44705.673875080785 40107.90588536175 0.7626549323477766 0.8579390961575483 1.0331843100046816 1.1325121838868275 0.8904032193265957 1.0128672141660615 0.9894964405383612 1.0284892650351452 1.1146349550849297 1.0 15.291599021651187 -5.101883290338818 3.1281037624582764 1.0235836280979256 0.7738459463877372 0.6574233903540081 0.06364799247555117 0.15823884026777368 2.836905518810104 0.017092316332258772 0.06445706918068969 7.908911387249103e-06 5.101883290338818 -0.2497376817101884 MEES(ph)FSSK ddPTM_PC-9_Lapatinib_30min_R1 2 MEESFSSK 8 0 G5E972;P42167;H0YJH7;P42167-2 G5E972 TMPO Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 MEES(0.985)FS(0.015)SK;MEES(0.942)FS(0.024)S(0.033)K 94.40899999999999 0.0067423000000000005 12094400.0 142021.0 140726.0 68137.0 50539.0 56361.0 71327.0 64207.0 53339.0 87209.0 28398.0 True False 139995.7544965381 140400.15759317967 62535.038876426115 54255.80665316171 53045.95678998936 68276.51048135804 67531.32429273613 55817.324663592895 77386.60406851774 33306.556462043525 4.203249130725316 4.2153909772444065 1.8775594213016784 1.6289827714549883 1.5926580957248175 2.0499420454698347 2.0275684869943094 1.675865973331793 2.3234645754119994 1.0 15.023518582197513 -5.265701163305401 6.668304475809232 1.8001699855616966 4.222357938451594 0.8946847894643674 0.334440584157434 0.034309408235115704 9.268498334300077 0.08239928823953106 0.19259358650899464 5.423739678859966e-06 5.265701163305401 2.4221879528898977 MEGGGAEVHAQLPS(ph)LEGDLRGPDVK ddPTM_PC-9_AZD4547_30min_R2 1 MEGGGAEVHAQLPSLEGDLRGPDVK 25 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 MEGGGAEVHAQLPS(1)LEGDLRGPDVK 52.09 0.0077733 2934200.0 10383.0 10701.0 13288.0 19146.0 18525.0 15973.0 13031.0 17862.0 12984.0 18037.0 True False 13684.578020183646 14159.888980539603 13111.792437775044 14732.185502751277 15953.123514776104 14974.205784940596 14190.733755608038 15101.838327926609 13670.307732638646 17405.530120035524 0.7862201223294724 0.8135281650652019 0.7533118696960598 0.8464083197209284 0.9165548767981762 0.8603131120783142 0.8153002900654586 0.8676459851425534 0.7854002514351884 1.0 14.08725813442687 -14.522878745280336 0.2204579302727348 1.8407780494844708 0.8092552919337692 0.5589347486796977 0.04561644518829286 125.82689389280453 1.2557172160167045 47.20049345667608 0.09299550299733866 3.0000000000000132e-15 14.522878745280336 -1.0315227575507016 MEGS(ph)DFESSGGR ddPTM_PC-9_AZD4547_30min_R2 1 MEGSDFESSGGR 12 0 A0A1B0GW41;Q8WYH8-2;Q8WYH8;E9PEN0 A0A1B0GW41 ING5 Inhibitor of growth protein 5 1 MEGS(1)DFESSGGR 152.0 0.00019493 5112200.0 15953.0 17613.0 16494.0 22276.0 25505.0 25983.0 28647.0 23539.0 18857.0 23829.0 True False 21025.72215698638 23306.057809012604 16275.27878301186 17140.61236076922 21964.070998346262 24358.27890253 31196.52750340754 19901.588422408702 19853.742522671502 22994.7539629831 0.9143703903435338 1.0135380376989742 0.7077822536919405 0.7454140361041539 0.9551774736839529 1.0592972180412061 1.3566802042599644 0.8654838601207141 0.8634031290194281 1.0 14.489017140942742 -6.511374051560728 5.205515074454161 1.0387610817153903 0.8469045721159312 0.24779250820071475 0.15029551136865757 0.27354266979541786 22.6416685547456 0.05279128981855985 0.056445331623283836 3.080533588272718e-07 6.511374051560728 -0.1918565095994591 MEGS(ph)DFESSGGR ddPTM_PC-9_Lapatinib_30min_R1 2 MEGSDFESSGGR 12 0 A0A1B0GW41;Q8WYH8-2;Q8WYH8;E9PEN0 A0A1B0GW41 ING5 Inhibitor of growth protein 5 1 MEGS(1)DFESSGGR;MEGS(1)DFESSGGR 154.23 0.00018407 11692900.0 41216.0 47149.0 48844.0 46844.0 55516.0 50336.0 53182.0 46555.0 50482.0 42834.0 True False 40628.252281911315 47039.829387325924 44828.23486329246 50289.06402700308 52250.65802865545 48183.246618947065 55935.50373847551 48718.115257383244 44796.18556097316 50237.79982728264 0.8087187819050813 0.9363433420462018 0.8923208225163475 1.0010204308289115 1.0400666073811555 0.9591034397326491 1.1134146784051364 0.9697501766573364 0.8916828705672277 1.0 15.616485662095585 -4.63778409011598 0.8613625014936818 0.9996282635034057 0.6830936467197053 0.4642731288288148 0.05946400697835437 2.657367453961834 1.2964147706671298 0.02184746033169185 0.8462712055749617 2.3025862656923262e-05 4.63778409011598 -0.31653461678370043 MEIGDTLSTAEES(ph)SPPK ddPTM_PC-9_AZD4547_30min_R2 1 MEIGDTLSTAEESSPPK 17 0 Q9BYW2;C9JG86;Q9BYW2-3;Q9BYW2-2 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 MEIGDTLSTAEES(0.894)S(0.106)PPK 194.55 3.9414e-12 12463000.0 42261.0 41805.0 32461.0 37337.0 37891.0 36914.0 47913.0 39572.0 40640.0 34002.0 True False 55699.118916592626 55317.64870866813 32030.545930359396 28729.531500899633 32630.48869626887 34605.76174452499 52177.164180220105 33457.05667409652 42788.14743179565 32811.60032940331 1.6975435016096803 1.685917424121998 0.9761957846858208 0.8755906817246696 0.9944802560278616 1.0546807042969462 1.5902047951456615 1.0196715898710618 1.3040554865424259 1.0 15.001918340092447 -5.252963943227932 24.257879797433 1.1064023531822145 1.6917306171630586 0.5958639198977003 0.19428647252682266 295.76917209763474 846524.5999344724 0.05260770117368369 0.1341979470278382 5.585165629714978e-06 5.252963943227932 0.5853282639808441 MEIGDTLSTAEES(ph)SPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 MEIGDTLSTAEESSPPK 17 0 Q9BYW2;C9JG86;Q9BYW2-3;Q9BYW2-2 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 MEIGDTLSTAEES(0.909)S(0.091)PPK;MEIGDTLSTAEES(0.64)S(0.359)PPK;MEIGDTLSTAEES(0.912)S(0.088)PPK;MEIGDTLSTAEES(0.912)S(0.088)PPK 223.14 6.7565e-29 26187700.0 172534.0 203742.0 150779.0 180840.0 177938.0 126693.0 179948.0 128108.0 121397.0 127866.0 True False 201740.59849816852 223968.15927603113 154374.14319254155 170708.1210911901 143072.32623862088 120048.99604972024 162902.02272930008 124745.30074164565 123172.20146443938 151047.09361330068 1.3356139047246385 1.4827703990744598 1.0220265713139673 1.1301648843917786 0.947203437127389 0.7947785897626113 1.0784849865853725 0.8258702485266557 0.8154556206144258 1.0 17.20463889901893 -5.492237907744744 1.075000944119957 0.9025553772290474 1.4650007574264294 0.7192312322587814 0.11363080118692549 0.3603707368993561 0.6897628072914134 0.03921398546757507 0.1770676054402433 3.2193047639087476e-06 5.492237907744744 0.562445380197382 MEIGDTLSTAEES(ph)SPPK ddPTM_PC-9_Lapatinib_30min_R1 2 MEIGDTLSTAEESSPPK 17 0 Q9BYW2;C9JG86;Q9BYW2-3;Q9BYW2-2 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 MEIGDTLSTAEES(0.963)S(0.037)PPK;MEIGDTLSTAEES(0.92)S(0.08)PPK 201.16 8.5724e-13 14576400.0 75718.0 125228.0 92762.0 105217.0 110428.0 109613.0 124843.0 117276.0 93370.0 102374.0 True False 74638.24743501926 124938.0422599856 85135.46643167498 112955.00917362259 103932.84214980122 104925.10751038296 131306.7596785095 122725.07109708709 82853.68737031141 120069.20949521947 0.6216268746067739 1.0405502192046994 0.7090532767692173 0.9407491699869971 0.8656077822677701 0.8738718939809504 1.093592272577904 1.0221194227315484 0.6900494116571178 1.0 16.87350670871301 -4.745084558424854 24.97509756778328 0.9128679345172475 0.6216260320517679 0.32049540736199666 0.12814525117406622 1190.7437419417365 1818260.4937165852 0.031215132150636333 0.8293929803252676 1.7985207037162697e-05 4.745084558424854 -0.29124190246547954 MEIGDTLSTAEES(ph)SPPKSR ddPTM_PC-9_AZD4547_30min_R2 1 MEIGDTLSTAEESSPPKSR 19 1 Q9BYW2;C9JG86;Q9BYW2-3;Q9BYW2-2 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 MEIGDTLS(0.002)T(0.01)AEES(0.572)S(0.402)PPKS(0.014)R 63.536 0.019462 10856000.0 42487.0 34844.0 39269.0 81536.0 57698.0 51100.0 41409.0 48437.0 35584.0 49883.0 True False 55996.98221550059 46106.64158844237 38748.26740209121 62739.13491864252 49687.628639975745 47904.70892195987 45094.3207801376 40952.17462153071 37464.897593824186 48136.6113532035 1.1632929830606777 0.9578289848891485 0.8049645854332143 1.3033558689516522 1.032221156478831 0.9951824105452284 0.9367988213639921 0.8507490134908579 0.7783035934732636 1.0 15.554846964319875 -7.334326027004069 2.0379889492311745 0.8631851429241518 1.0445055614334542 0.25194482579906485 0.13169360132023797 0.48405922764689263 3.9226718194103687 0.0708999978018292 0.042734030058770314 4.630991384106317e-08 7.334326027004069 0.18132041850930236 MEIGDTLSTAEES(ph)SPPKSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MEIGDTLSTAEESSPPKSR 19 1 Q9BYW2;C9JG86;Q9BYW2-3;Q9BYW2-2 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 MEIGDTLS(0.001)T(0.002)AEES(0.498)S(0.498)PPKS(0.001)R 56.485 0.043522000000000005 7879800.0 35258.0 19337.0 20295.0 51768.0 45899.0 43771.0 42138.0 56422.0 46150.0 39656.0 True False 41226.483022757406 21256.649566219075 20778.909769216112 48867.60679412051 36905.42043872839 41475.57170555832 38146.383587298835 54940.982284050515 46824.85644277776 46845.31888327675 0.8800555531595452 0.45376251187837385 0.4435642720458447 1.0431694768880246 0.7878144779136771 0.8853728119324349 0.814305132223503 1.1728169130611645 0.9995631913500264 1.0 15.515617270309125 -6.401721205119792 0.7025606989318482 1.0323987941885815 0.5919888722121822 0.4051785489460541 0.17516741036534228 0.7525566974473779 0.8183370555726753 0.11700717429496676 0.17897588581413784 3.965325061878154e-07 6.401721205119792 -0.4404099219763993 MEIGDTLSTAEESS(ph)PPK ddPTM_PC-9_AZD4547_30min_R2 1 MEIGDTLSTAEESSPPK 17 0 Q9BYW2;C9JG86;Q9BYW2-3;Q9BYW2-2 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 MEIGDTLSTAEES(0.213)S(0.787)PPK 151.38 3.9071e-05 13050000.0 30734.0 32554.0 23407.0 23982.0 25057.0 29293.0 29478.0 31320.0 31081.0 27673.0 True False 40506.77269308717 43076.44387183309 23096.6078861379 18453.320418206484 21578.26806530336 27461.304079275353 32101.484893547233 26480.21366200097 32723.878206880894 26704.176693005662 1.5168703067972389 1.6130976201605063 0.8649061961976662 0.6910274984452063 0.8080484305271664 1.0283523957684118 1.2021147576496987 0.9916131834514355 1.2254217227169526 1.0 14.70477778524635 -5.258109355481738 24.980106274331366 0.9698431664583737 1.5649840244310387 0.6945058130812968 0.15608797789135317 165.69345938674908 1242931.6484190482 0.04516499400976891 0.10980965788824115 5.519384435150927e-06 5.258109355481738 0.595140857972665 MEIGDTLSTAEESS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 2 MEIGDTLSTAEESSPPK 17 0 Q9BYW2;C9JG86;Q9BYW2-3;Q9BYW2-2 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 MEIGDT(0.004)LS(0.023)T(0.006)AEES(0.228)S(0.739)PPK;MEIGDTLSTAEES(0.26)S(0.74)PPK 136.39 4.9633000000000004e-05 14167900.0 83542.0 131547.0 93295.0 104968.0 123457.0 107316.0 128398.0 117508.0 99783.0 100266.0 True False 82350.67576027347 131242.41100372357 85624.64522911464 112687.69688298319 116195.50198580066 102726.34484581454 135045.8201837608 122967.85066404434 88544.3877784277 117596.8445039531 0.7002796385195964 1.1160368422922415 0.7281202619874405 0.9582544273047658 0.9880835023757347 0.8735467799253859 1.1483796249245544 1.0456730466089221 0.7529486709607349 1.0 16.84348982305007 -5.970549211907211 24.980386541246055 0.9745379122656743 0.8696434359224194 0.12011716083612833 0.14312112539079574 484.53281156587576 410981.3924878712 0.038953390188166646 0.057776488077434775 1.0701651107048868e-06 5.970549211907211 -0.10489447634325488 MEISAELPQT(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 2 MEISAELPQTPQR 13 0 H3BS20;H3BNQ6;A0A087WTJ9;Q8IWV7-2;Q8IWV7 H3BS20 UBR1 E3 ubiquitin-protein ligase UBR1 1 MEIS(0.001)AELPQT(0.999)PQR;MEIS(0.004)AELPQT(0.996)PQR 88.163 0.025745 9099500.0 34705.0 40612.0 50625.0 55945.0 53331.0 51623.0 42746.0 57039.0 51094.0 50163.0 True False 45740.46809115609 53739.034789054705 49953.67942221264 43047.7445916338 45926.911210068785 48395.00564928248 46550.3111900254 48224.93317582611 53794.72452953167 48406.80863842891 0.9449180678860932 1.1101544658821543 1.03195564482133 0.8892911101241098 0.9487696566224074 0.9997561708883849 0.9616480098436052 0.9962427710539378 1.1113049185156452 1.0 15.56292236295953 -10.352438510000539 6.930013604930548 0.9999999999993631 0.9976453022398414 0.0 0.06705659455245444 4.832949295241613e-11 1.8082169937092306e-18 0.06715290075718941 0.01628697051545301 4.441825469242292e-11 10.352438510000539 -0.0023546977595216845 MEISAELPQT(ph)PQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MEISAELPQTPQR 13 0 H3BS20;H3BNQ6;A0A087WTJ9;Q8IWV7-2;Q8IWV7 H3BS20 UBR1 E3 ubiquitin-protein ligase UBR1 1 MEIS(0.001)AELPQT(0.999)PQR;MEISAELPQT(1)PQR 103.3 0.0058582 6918000.0 60029.0 61811.0 57166.0 79576.0 72894.0 68044.0 69822.0 61823.0 64317.0 52886.0 True False 70190.72407320628 67947.18758533205 58529.05424326232 75117.61470887286 58610.94397395738 64475.65285538394 63207.95469249564 60200.21175688304 65257.51444919039 62473.81315465436 1.1235223292589593 1.0876106988559882 0.93685740133027 1.2023856223233675 0.9381681862265328 1.032042860834731 1.0117511882302415 0.9636071294040753 1.044557890001767 1.0 15.930963968543963 -6.302923084904567 24.9999782412859 0.9988891626234624 1.0768285982944021 0.2887330703960561 0.06777640877782959 715.5146918292245 431200.0961676048 0.020287243670272778 0.02300390723805698 4.978252437911219e-07 6.302923084904567 0.07793943567093975 MEISAELPQT(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 2 MEISAELPQTPQR 13 0 H3BS20;H3BNQ6;A0A087WTJ9;Q8IWV7-2;Q8IWV7 H3BS20 UBR1 E3 ubiquitin-protein ligase UBR1 1 MEISAELPQT(1)PQR;MEISAELPQT(1)PQR 104.81 0.0031758000000000003 4054400.0 32765.0 42660.0 40054.0 32596.0 35963.0 36315.0 34578.0 33147.0 31514.0 24841.0 True False 32297.76509163489 42561.22339102259 36760.91473291123 34993.21857706838 33847.72704597838 34761.892104399674 36368.279648546595 34687.13062907277 27964.561462868114 29134.733751448122 1.1085656511286825 1.4608413364651776 1.2617556435052046 1.2010824905969517 1.1617654492653808 1.1931426043209288 1.2482791145032837 1.190576544305941 0.9598358338002027 1.0 14.8304525061873 -8.187274141341923 3.9703965021614436 0.9776267885622851 1.2367529819194845 0.562054785384088 0.08810165379175156 0.16455640175294436 4.784289242761641 0.07081942523699329 0.02332455931611739 6.4971943602624205e-09 8.187274141341923 0.25912619335719933 MELAGSNTTAS(ph)SPAR ddPTM_PC-9_AZD4547_30min_R2 2 MELAGSNTTASSPAR 15 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 MELAGS(0.001)NT(0.001)T(0.041)AS(0.506)S(0.451)PAR;MELAGS(0.022)NT(0.004)T(0.002)AS(0.486)S(0.486)PAR 111.07 0.00040553 5308900.0 30026.0 29880.0 50055.0 53386.0 47730.0 46194.0 38625.0 53797.0 41281.0 41726.0 True False 39573.643420402 39538.12566475312 49391.23799464403 41078.682505477926 41103.5133797713 43305.48187751494 42062.55017346025 45483.90978207747 43463.02938316816 40265.185440405934 0.9828253114336839 0.9819432155173136 1.2266487153708756 1.0202034848759358 1.020820168346328 1.0755068281408704 1.0446381834181415 1.1296088490489 1.0794195756901497 1.0 15.297245357258957 MELAGSNTTAS(ph)SPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MELAGSNTTASSPAR 15 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 MELAGS(0.001)NT(0.003)T(0.006)AS(0.495)S(0.495)PAR;MELAGS(0.031)NT(0.031)T(0.031)AS(0.453)S(0.453)PAR 128.85 1.4805999999999999e-05 17752600.0 68588.0 63167.0 79079.0 69049.0 91544.0 74850.0 66312.0 63821.0 67983.0 57456.0 True False 80198.59372525057 69437.80230384023 80964.54326877749 65180.40838987843 73606.61035410251 70924.7342341057 60030.447302695015 62145.76637393909 68977.12276379991 67872.31797855429 1.1816097654214643 1.0230651371856874 1.1928949191680762 0.9603386230373563 1.0844864673306147 1.044972918952258 0.8844614283199068 0.9156275816832332 1.0162776934418936 1.0 16.050535664503457 -6.392098164890721 0.8342195947040894 0.9524154824836686 1.1222345076030433 0.41646339955691014 0.07365296209367364 0.6170113312056431 0.9407851948394993 0.040597986369350796 0.058192065503184384 4.054168874900237e-07 6.392098164890721 0.16981902511937474 MELAGSNTTAS(ph)SPAR ddPTM_PC-9_Lapatinib_30min_R1 1 MELAGSNTTASSPAR 15 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 MELAGS(0.021)NT(0.07)T(0.07)AS(0.51)S(0.329)PAR 69.805 0.022019999999999998 3805600.0 12642.0 13131.0 13589.0 13175.0 14359.0 13521.0 12600.0 10462.0 13209.0 11592.0 True False 12461.722761741126 13100.595976266235 12471.764875056928 14143.9334505116 13514.43185088017 12942.738348990451 13252.366347726507 10948.102713408733 11721.263323063562 13595.661754630917 0.9165955277974203 0.9635864890360298 0.9173341540957968 1.0403269591267914 0.9940253071004007 0.9519756068204573 0.9747496360898007 0.805264422651558 0.8621326077835894 1.0 13.730858754294923 -7.732697339894697 24.99361517676211 0.8752738496050092 0.9670396311400573 0.2667822148418979 0.056606916355291775 216.58295701860845 188337.22832419723 0.026022148299526187 0.015020446143255223 1.850557824646547e-08 7.732697339894697 0.09176578153504811 MELAGSNTTASS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 3 MELAGSNTTASSPAR 15 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 MELAGSNTT(0.002)AS(0.097)S(0.901)PAR;MELAGSNT(0.001)T(0.001)AS(0.214)S(0.784)PAR;MELAGS(0.013)NT(0.013)T(0.013)AS(0.47)S(0.49)PAR 143.93 5.3202e-07 23773600.0 41192.1 38975.5 60738.0 80951.0 68353.0 58326.0 47527.0 74747.0 49020.0 58459.0 True False 54290.330951093805 51573.568167556434 59932.57443449582 62288.99763048258 58863.36580866342 54678.865999652284 51756.81092800117 63196.56866518475 51611.09712368658 56412.36820353474 0.962383475113389 0.9142244832104902 1.0624013198357538 1.104172712724009 1.043447876470733 0.9692708840439386 0.9174727559967629 1.1202608696939074 0.9148897443460402 1.0 15.783723882416346 -5.253307121823895 24.949724628873806 1.0196561998610068 0.938303975203522 0.1768228116874071 0.06720095964654833 995.0775457326278 3052876.5916468217 0.017341570807339907 0.04418800460299536 5.580753986720542e-06 5.253307121823895 -0.0813522246574847 MELAGSNTTASS(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MELAGSNTTASSPAR 15 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 MELAGSNTTAS(0.234)S(0.765)PAR 144.15 9.1889e-05 9778900.0 15629.0 11796.0 16347.0 15779.0 20295.0 14478.0 17169.0 14511.0 15790.0 11190.0 True False 18274.6810131793 12967.028922951857 16736.774476342736 14894.953786208216 16318.340438876512 13718.748192937632 15542.628027204284 14130.101625675397 16020.898878254833 13218.658420008742 1.3824913567262913 0.9809640669225554 1.266147739396058 1.1268128211605883 1.2344929356957937 1.0378321125366186 1.175809793502025 1.068951263941205 1.2119912905839532 1.0 13.690288142702554 -14.522878745276435 0.05606232189910069 0.4617355954858939 1.4041981937034547 0.19941092052817933 0.10955960273563492 792.2838505421932 3.248926708930286 61.6801281477605 11.48692470217293 3.0000000000269596e-15 14.522878745276435 0.9424625982175607 MELAGSNTTASS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 4 MELAGSNTTASSPAR 15 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 MELAGS(0.023)NT(0.234)T(0.156)AS(0.234)S(0.354)PAR;MELAGSNTT(0.001)AS(0.241)S(0.758)PAR;MELAGSNTTAS(0.081)S(0.919)PAR;MELAGSNTTAS(0.326)S(0.674)PAR 184.0 2.4829999999999997e-29 8943500.0 108609.0 92919.0 106949.0 97656.0 88700.0 90391.0 78207.0 70545.0 94222.0 84251.0 True False 107060.21574354854 92703.85176442644 98156.0660550785 104837.94801086598 83482.84039090954 86525.18764171263 82256.17579021 73822.778237184 83609.72615835367 98813.67309259903 1.0834554813403365 0.9381682601511329 0.99334497932382 1.0609660053080059 0.844851099833898 0.8756398273003093 0.8324371842055414 0.7470907206131698 0.8461351910276869 1.0 16.59242306445706 -6.27259535579782 23.96802123404286 0.8446814724700811 1.0113798138587453 0.5598961310799524 0.06935212188726113 296.8288604390646 637719.4532193532 0.021019219957504054 0.024070083819006934 5.338320499576723e-07 6.27259535579782 0.16669834138866424 MELQEIQLK ddPTM_PC-9_Lapatinib_30min_R1 2 MELQEIQLK 9 0 A0A087WWU8;P06753-5;P06753-2;P06753-4;P06753-3;P06753-6;P06753-7;J3KN67;A0A494C0P6;A0A2R2Y2Q3;P06753 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 ; 125.48 0.0065666 7381300.0 54150.0 54777.0 61354.0 60176.0 59343.0 45128.0 57446.0 53767.0 56907.0 60458.0 False True 53377.81107010618 54650.16722198888 56309.71095328894 64601.54378125128 55852.56141282692 43197.980638506095 60420.27279456322 56265.211106083676 50497.534402723715 70908.08474477875 0.7527746837646268 0.7707184225704671 0.7941225765152999 0.9110603397873915 0.7876755043357672 0.6092109354524194 0.8520928609485847 0.7934950056626189 0.7121548210543376 1.0 16.113662508512625 -11.326356193652346 3.108951186025833 1.0542541826881016 0.7784791498367404 0.4404981262285955 0.0757120265056543 685378956.8013865 166606886.39269468 270244730.41535795 0.019450990699708057 4.7167602984419245e-12 11.326356193652346 -0.2757750328513612 MENDFLPS(ph)LELSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MENDFLPSLELSR 13 0 A0A2R8YCN4;A0A2R8YG38;Q01968-2;Q01968 A0A2R8YCN4 OCRL Inositol polyphosphate 5-phosphatase OCRL-1 1 MENDFLPS(1)LELSR 72.243 0.024038999999999998 11209000.0 26759.0 32639.0 38745.0 51046.0 59335.0 56836.0 43994.0 63880.0 38253.0 29899.0 True False 31288.77018565903 35879.18421636367 39668.827741230765 48186.05811336491 47708.732689861405 53855.42010594028 39826.5698310225 62203.21768645471 38812.37775743398 35319.45201964622 0.8858792647251393 1.0158477033110849 1.1231439185173437 1.3642923476434947 1.3507778281306213 1.5248090507175351 1.1276100718909576 1.7611603275117227 1.0988952415186068 1.0 15.108175339334478 -5.4491716195023265 1.7688903721191278 1.3546998491759121 0.915220328921511 0.3234201273238998 0.21094859446321312 0.3975230630230897 2.337626171396678 0.05815460069057311 0.1844844750366709 3.5549081203523355e-06 5.4491716195023265 -0.4394795202544012 MEPPGPVR ddPTM_PC-9_AZD4547_30min_R2 1 MEPPGPVR 8 0 I3L4J6 I3L4J6 ZNF232 0 64.207 0.046278 2452500.0 6849.0 8194.0 8921.4 10233.0 10307.0 8925.3 7226.2 11991.0 7771.3 10371.0 False True 9026.83953195009 10842.550257596617 8803.096406860795 7873.939948273995 8876.050961770434 8367.199580061997 7869.317800995693 10138.066475768 8182.07505257661 10007.914446686726 0.9019700937729903 1.0833975765236692 0.8796134752905683 0.7867713088695302 0.8869031613983258 0.8360582641503382 0.7863094596697868 1.0130049102412506 0.8175604513970852 1.0 13.28885374124532 -5.396011545012808 8.322335809693305 0.8681102119838959 0.9921349121989614 0.2298111073476693 0.08491463314753345 0.3581014292527747 22.412281707633756 0.0211084338850207 0.04407995301114125 4.017801300353554e-06 5.396011545012808 0.12402470021506551 MEPQS(ph)PGEVKK ddPTM_PC-9_AZD4547_30min_R2 1 MEPQSPGEVKK 11 1 Q03112;Q03112-3;E7EUL6;A0A0C3SFZ7;Q03112-8;Q03112-5;Q03112-6;Q03112-1;Q03112-4;H9KVD4 Q03112 MECOM MDS1 and EVI1 complex locus protein EVI1 1 MEPQS(1)PGEVKK 55.335 0.031742 9452200.0 83719.0 67421.0 88230.0 113480.0 81207.0 82826.0 83318.0 105360.0 86891.0 89548.0 True False 110339.90053662275 89213.51976048588 87060.01255154221 87318.93924852266 69932.80978485403 77646.87712661925 90733.14059164672 89079.03293194214 91483.88086850777 86412.95177628995 1.276890770058128 1.0324091230148715 1.0074880068548915 1.0104843944525606 0.8092862047566607 0.8985560096087825 1.0499946909178741 1.0308527958002671 1.0586825121463932 1.0 16.398959942667865 -4.430279161428125 1.5862555663384652 0.9764330483837583 1.7027571286990695 0.5968994290121392 0.07194098489821764 2.1638480096814794 2.520143472088093 0.022246906940393732 3.1971172842735234 3.7129648561338935e-05 4.430279161428125 0.7263240803153111 MEPQS(ph)PGEVKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MEPQSPGEVKK 11 1 Q03112;Q03112-3;E7EUL6;A0A0C3SFZ7;Q03112-8;Q03112-5;Q03112-6;Q03112-1;Q03112-4;H9KVD4 Q03112 MECOM MDS1 and EVI1 complex locus protein EVI1 1 MEPQS(1)PGEVKK 53.136 0.035703 7282000.0 59661.0 78242.0 59540.0 75221.0 91556.0 88737.0 100510.0 89108.0 81958.0 72870.0 True False 69760.42894153757 86009.34867663617 60959.659406707404 71006.61123977223 73616.25904024525 84083.4755074394 90988.96517061575 86769.00941773015 83156.48070069743 86080.7541613973 0.8104068048792893 0.9991704825839787 0.7081682775735324 0.824883702884831 0.8551999777118389 0.9767976166866162 1.0570186803895303 1.0079954603446248 0.9660287193207323 1.0 16.39340309708318 -6.790452195606726 3.6212832109409323 1.0094031245502169 0.8382853631787068 0.5804308454088087 0.06935863147229014 0.1708734277570462 4.715341878745231 0.025336255652724977 0.02319520033689553 1.6201223169199873e-07 6.790452195606726 -0.17111776137151002 MEPQS(ph)PGEVKK ddPTM_PC-9_Lapatinib_30min_R1 1 MEPQSPGEVKK 11 1 Q03112;Q03112-3;E7EUL6;A0A0C3SFZ7;Q03112-8;Q03112-5;Q03112-6;Q03112-1;Q03112-4;H9KVD4 Q03112 MECOM MDS1 and EVI1 complex locus protein EVI1 1 MEPQS(1)PGEVKK 62.287 0.020741 11184000.0 96810.0 80644.0 99352.0 89486.0 111000.0 112730.0 97663.0 102200.0 105840.0 94246.0 True False 95429.47164722052 80457.27377275271 91183.66206981082 96067.09895654497 104471.19823439643 107908.80068646489 102719.51227127094 106948.58509944279 93919.18465539004 110536.29552509877 0.8633315527165641 0.7278810402550879 0.8249205533498842 0.8691000408524784 0.9451302645715571 0.9762295739498772 0.9292831081709906 0.9675426934780771 0.8496682850572318 1.0 16.754160642932682 -5.953820521587857 2.1767004964268404 0.9439471944588641 0.7939604292927339 0.6258831852363922 0.048602830722376 0.18838488021782268 1.8038990546451577 0.0146062659365606 0.02364321532415686 1.1121912612817542e-06 5.953820521587857 -0.1499867651661302 MEPTYQLS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 MEPTYQLSR 9 0 R4GMY7;M0R1A1;Q15833-2;Q15833;Q15833-3 R4GMY7 STXBP2 Syntaxin-binding protein 2 1 MEPT(0.107)Y(0.078)QLS(0.815)R 69.423 0.028016000000000003 982920.0 0.0 0.0 730.7 0.0 0.0 529.64 0.0 0.0 453.68 0.0 True False 0.0 0.0 670.6246665835678 0.0 0.0 506.98853185114257 0.0 0.0 402.5817809378058 0.0 0.0 MES(ph)SPFNRR ddPTM_PC-9_Lapatinib_30min_R1 2 MESSPFNRR 9 1 Q9UHB6;Q9UHB6-4;F8VRN8;F8VTU2;F8VVQ7 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 MES(1)SPFNRR;MES(0.999)S(0.001)PFNRR 62.54600000000001 0.029299000000000002 587910.0 11123.7 8842.3 16226.800000000001 8713.3 12016.400000000001 11944.3 11581.5 10866.6 13840.599999999999 8450.5 True False 10965.073998163258 8821.826197619288 14892.695141259399 9354.105148716711 11309.618977151378 11433.47013252322 12181.133401285277 11371.501906473653 12281.725880020702 9911.157665416535 1.106336350235271 0.8900903905909698 1.5026191333052017 0.9437954136635751 1.1410996937940519 1.1535958279039957 1.2290323504578555 1.147343457783218 1.239181768127441 1.0 13.27483786483983 -6.681935306789229 4.3441905035884645 1.1679495959697352 1.1145457149745632 0.010490317926998505 0.16374315777099774 1.1593339751231375 40.9665952280661 0.0544951815865463 0.053575801315359745 2.080006505171941e-07 6.681935306789229 -0.053403880995172015 MESEGGADDS(ph)AEEGDLLDDDDNEDRGDDQVK ddPTM_PC-9_Lapatinib_30min_R1 1 MESEGGADDSAEEGDLLDDDDNEDRGDDQVK 31 1 B4DY08 B4DY08 HNRNPC 1 MESEGGADDS(1)AEEGDLLDDDDNEDRGDDQVK 151.67 1.3590000000000003e-26 0.0 9014.8 8195.9 9982.2 6459.7 7861.8 8839.7 6921.7 7494.8 7862.1 6701.4 True False 8886.247298888149 8176.922897104599 9161.50204840631 6934.767886927495 7399.384380893498 8461.646637347154 7280.071757861794 7843.0357691125755 6976.587506416689 7859.728060945792 1.1306049306009744 1.0403569733837124 1.1656258304824696 0.8823165169524971 0.9414300753813996 1.0765826211459193 0.9262498271455151 0.9978762252709278 0.8876372633148288 1.0 12.940263682144456 -5.756890419720594 24.99999979558496 0.9616006796665402 1.1050120210805734 0.5644557681610061 0.061590357199251336 87.60602093407253 481454.27775120427 0.016574296922917234 0.027517565469205647 1.7502882620037775e-06 5.756890419720594 0.14341134141403322 MESMNRPYTSLVPPLS(ph)PQPK ddPTM_PC-9_AZD4547_30min_R2 1 MESMNRPYTSLVPPLSPQPK 20 1 C9K0J5;Q70E73 C9K0J5 RAPH1 Ras-associated and pleckstrin homology domains-containing protein 1 1 MES(0.013)MNRPY(0.01)T(0.011)S(0.011)LVPPLS(0.955)PQPK 51.232 0.021616 7617700.0 19236.0 21583.0 30252.0 38048.0 29678.0 29135.0 24734.0 30160.0 28041.0 31839.0 True False 25352.64786634426 28559.282671431265 29850.83871369434 29276.621435740155 25557.7219795695 27313.183844252446 26935.278083892954 25499.4650078528 29523.1900131639 30724.326301037367 0.8251652979446538 0.9295332431900061 0.9715701630432972 0.9528808263812661 0.8318399475762167 0.8889758420294557 0.8766759544206351 0.8299438288087653 0.9609060170724424 1.0 14.907093756207326 -8.491400949595771 7.758321009448447 0.9999829588312069 0.8924536816913786 0.37518839342746346 0.04863958164365908 0.23719927573917118 50.03723395514102 0.04984484788202613 0.012886521864048673 3.225514885012218e-09 8.491400949595771 -0.1075292771398283 MESMNRPYTSLVPPLS(ph)PQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MESMNRPYTSLVPPLSPQPK 20 1 C9K0J5;Q70E73 C9K0J5 RAPH1 Ras-associated and pleckstrin homology domains-containing protein 1 1 MES(0.001)MNRPY(0.004)T(0.005)S(0.005)LVPPLS(0.985)PQPK;MESMNRPYTSLVPPLS(0.999)PQPK 53.278 0.015012000000000001 19306300.0 27458.9 24463.5 33089.0 45895.0 68080.0 68597.0 74046.0 86359.0 78326.0 64148.0 True False 32107.14943200392 26892.074606360864 33877.9672507313 43323.651943597564 54740.21271636926 64999.652561883086 67031.82683338397 84092.16775492394 79471.3695717662 75777.52460471129 0.42370280105465113 0.3548819355955699 0.44707144271937616 0.5717216571746396 0.7223805871453066 0.8577695418390836 0.8845871804740428 1.1097243964300163 1.0487459175570015 1.0 16.209482392201075 -6.51601874989278 0.7817900238231653 1.0608236390410593 0.3575657675727742 0.9663319788330608 0.04844748852382992 0.10644469190151067 0.1445227951599712 0.03044542772561815 0.038699184080643094 3.047763405016543e-07 6.51601874989278 -0.7032578714682851 down MESMNRPYTSLVPPLS(ph)PQPK ddPTM_PC-9_Lapatinib_30min_R1 1 MESMNRPYTSLVPPLSPQPK 20 1 C9K0J5;Q70E73 C9K0J5 RAPH1 Ras-associated and pleckstrin homology domains-containing protein 1 1 MESMNRPYTSLVPPLS(1)PQPK 88.22200000000001 0.00033845 5386200.0 21872.0 19714.0 14743.0 13642.0 23910.0 28748.0 31315.0 26974.0 36552.0 34990.0 True False 21560.10126916645 19668.353444224544 13530.887449625754 14645.278188377928 22503.66080886864 27518.515054861124 32936.33747452822 28227.310513428325 32435.128850376193 41037.97487875566 0.5253695225669525 0.47927202797734453 0.32971625645763425 0.35687136686560583 0.5483618739802443 0.6705622082025976 0.8025819395775922 0.687833904982502 0.7903686511384619 1.0 15.324671918865205 -6.794945902114466 1.7829159798008092 0.7973571637971107 0.4207434174067753 0.7919327402671377 0.09137736747162803 0.16603524680914147 1.0901137759444892 0.039309496419386 0.03502726160827299 1.6034451113665955e-07 6.794945902114466 -0.37661374639033546 MESSFGS(ph)PSKQESSESLPK ddPTM_PC-9_Lapatinib_30min_R1 2 MESSFGSPSKQESSESLPK 19 1 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4;A8MV73 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 MES(0.002)S(0.027)FGS(0.297)PS(0.297)KQES(0.186)S(0.186)ES(0.004)LPK;MES(0.291)S(0.319)FGS(0.351)PS(0.038)KQESSESLPK 71.402 0.002991 129973000.0 152223.0 156118.0 135569.0 156222.0 166558.0 150849.0 141303.0 153175.0 141181.0 120281.0 True False 150052.27210572094 155756.51836286118 124423.04013147333 167711.08702131468 156761.38590562713 144397.5399161939 148618.9779391109 160292.06969282974 125279.70907816154 141071.41058564192 1.0636618112968177 1.10409697979382 0.88198621970919 1.1888382367843433 1.1112200923975315 1.023577628640303 1.0535017500862585 1.1362477274976939 0.8880588104852505 1.0 17.106066116621072 -8.264761168491772 24.99980289009089 0.9440294048395651 1.068420408300671 0.2803980867470346 0.08092270722762993 394.09010168751263 2965855.217558887 0.066338300327037 0.019938369430243973 5.435491632376458e-09 8.264761168491772 0.12439100346110588 MESSFGSPS(ph)KQESSESLPK ddPTM_PC-9_Lapatinib_30min_R1 1 MESSFGSPSKQESSESLPK 19 1 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4;A8MV73 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 MES(0.002)S(0.01)FGS(0.098)PS(0.808)KQES(0.031)S(0.049)ESLPK 78.419 0.0014657 16549000.0 17283.0 22292.0 17061.0 16151.0 23527.0 18239.0 18854.0 17268.0 17517.0 13486.0 True False 17036.54125068597 22240.3842436164 15658.310437364516 17338.798418156584 22143.188115861678 17458.960487185617 19830.167866669482 18070.33431993329 15544.050997812423 15817.03713103454 1.0771006674352837 1.4061030557978929 0.9899648276503956 1.0962102620430854 1.3999580283221706 1.1038072644420531 1.253722027860755 1.1424601314539222 0.9827410069938768 1.0 13.949191757066071 -8.17244538374534 3.785445338881892 0.9895055794644741 1.1917261168956912 0.26931030813766843 0.12824377226812084 0.30416072802844357 7.7374303101320985 0.09845163830140026 0.03239604495671987 6.722868496310133e-09 8.17244538374534 0.20222053743121704 MESSFGSPSKQES(ph)SESLPK ddPTM_PC-9_AZD4547_30min_R2 1 MESSFGSPSKQESSESLPK 19 1 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4;A8MV73 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 MES(0.006)S(0.039)FGS(0.035)PS(0.05)KQES(0.391)S(0.391)ES(0.088)LPK 46.159 0.041472 7417800.0 15766.0 14542.0 17484.0 16217.0 16451.0 16560.0 16998.0 19838.0 21354.0 17046.0 True False 20779.26004682803 19242.41711569076 17252.15073615734 12478.421200152377 14167.062614930184 15524.500582145896 18510.78907051073 16772.492931889385 22482.72884494497 16449.224728398593 1.2632364375783554 1.1698069321449474 1.0488123921349644 0.7586023904585082 0.8612602021584401 0.9437831167412883 1.1253289669362334 1.0196524887238418 1.366795652449802 1.0 14.005731969172462 -9.726044958365865 12.260586441729433 0.9999972870373298 1.0470318302140402 0.004840206153201909 0.1730067156557421 0.0 0.0 0.17962983667410215 0.04356663471292778 1.8791222791256724e-10 9.726044958365865 0.04703454317671041 MET(ph)EADAPSPAPSLGER ddPTM_PC-9_Lapatinib_30min_R1 2 METEADAPSPAPSLGER 17 0 Q12873;Q12873-3;Q12873-2 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 MET(0.958)EADAPS(0.042)PAPSLGER;MET(0.989)EADAPS(0.011)PAPSLGER 184.87 1.3135e-07 35144900.0 66997.0 57865.0 76591.0 55767.0 64516.0 66055.0 60879.0 64994.0 67880.0 47112.0 True False 66041.61049425481 57731.01714771501 70293.98362980984 59868.291213258446 60721.29572333622 63229.98163172579 64031.01673676525 68013.85851226219 60234.639591911095 55255.246427205966 1.1952097721844197 1.0448060750895511 1.27216849394412 1.0834860956077677 1.0989236253489758 1.1443253938795812 1.1588223902162955 1.230903179517344 1.0901162059111447 1.0 15.75382383292532 -8.530422013237768 23.245328471626344 0.9999999958554671 1.150296458180201 0.35362746606438866 0.06458080283770984 396.3126254085939 1221278.8286650637 0.0596748520957432 0.01540798054844589 2.9483428664108244e-09 8.530422013237768 0.15029646232473404 METEADAPS(ph)PAPSLGER ddPTM_PC-9_AZD4547_30min_R2 6 METEADAPSPAPSLGER 17 0 Q12873;Q12873-3;Q12873-2 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 MET(0.062)EADAPS(0.927)PAPS(0.011)LGER;MET(0.002)EADAPS(0.997)PAPS(0.001)LGER;METEADAPS(1)PAPSLGER;METEADAPS(1)PAPSLGER;METEADAPS(1)PAPSLGER;METEADAPS(1)PAPSLGER 217.32 1.9258000000000002e-22 123606000.0 162011.0 161396.0 216069.0 282276.0 255399.0 223724.0 163840.0 244131.0 192727.0 199902.0 True False 213527.12796185838 213564.10072920023 213203.7838830232 217201.62932072606 219941.25735764074 209734.50291304357 178421.44259986363 206406.16352228448 202914.15576003125 192903.4918254329 1.1069116786910667 1.1071033432741801 1.1052354826006 1.1259600708383322 1.1401621363944803 1.0872509405005577 0.9249259353030544 1.0699970309976077 1.051894674585038 1.0 17.5575197328764 -7.016108131652883 24.421313069753726 1.0159019054277396 1.1160915146993555 0.6445085532812389 0.037028304113355025 348.60291517269235 528511.137386274 0.013843799064133947 0.01104563261534367 9.635890770984722e-08 7.016108131652883 0.10018960927161591 METEADAPS(ph)PAPSLGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 METEADAPSPAPSLGER 17 0 Q12873;Q12873-3;Q12873-2 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 METEADAPS(0.994)PAPS(0.006)LGER;MET(0.002)EADAPS(0.792)PAPS(0.205)LGER;MET(0.499)EADAPS(0.501)PAPS(0.001)LGER 119.04 9.188700000000001e-05 93779600.0 77914.0 85443.0 99047.0 104328.0 133466.0 113432.0 106049.0 94551.0 90422.0 85045.0 True False 91103.30132835437 93925.21636688487 101408.65611783936 98482.84039593974 107314.29539369763 107483.42623437657 96003.27099172832 92069.13643506533 91744.25068838251 100462.98528415062 0.9068345029831314 0.9349236049598342 1.0094131269443567 0.9802898064136735 1.0681973573666828 1.069880871351466 0.9556083837265198 0.9164483433839435 0.9132144583290259 1.0 16.61630452526046 -10.613139461308638 4.365915811264996 1.0000025124230245 0.9764468488377833 0.01633125958511361 0.057316727198649844 1.567748033055038e-06 3.2674020559026907e-07 0.062056363161909274 0.015049273247165871 2.437028110507029e-11 10.613139461308638 -0.023555663585241193 METEADAPS(ph)PAPSLGER ddPTM_PC-9_Lapatinib_30min_R1 5 METEADAPSPAPSLGER 17 0 Q12873;Q12873-3;Q12873-2 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 MET(0.04)EADAPS(0.96)PAPS(0.001)LGER;MET(0.003)EADAPS(0.972)PAPS(0.025)LGER;METEADAPS(1)PAPSLGER;MET(0.023)EADAPS(0.977)PAPSLGER;METEADAPS(1)PAPSLGER 270.94 6.0971e-70 79849700.0 178405.0 144075.0 176878.0 148467.0 165223.0 166302.0 142318.0 152670.0 171621.0 129326.0 True False 175860.91198452955 143741.40318944183 162335.77360882462 159385.75845139349 155504.90798091626 159189.65112889637 149686.52967267775 159763.6055492363 152291.2357307509 151679.82678393734 1.1594218935589722 0.9476632867876127 1.0702528942102914 1.0508039324071288 1.0252181274074608 1.0495110292791705 0.9868585219701036 1.0532950158020289 1.0040309180184157 1.0 17.210669696250697 -4.738687202181337 24.998571345353433 1.0249637774508265 1.1594224411541096 0.5759357823484232 0.03551459739143424 1391.1983791543184 1528477.3134137944 0.008321350600033965 0.4563276073790871 1.8252098247033465e-05 4.738687202181337 0.1344586637032832 METVSNASSSSNPS(ph)SPGR ddPTM_PC-9_AZD4547_30min_R2 2 METVSNASSSSNPSSPGR 18 0 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 METVSNASSSSNPS(0.629)S(0.371)PGR;METVSNASSSSNPS(0.5)S(0.5)PGR 341.3 8.402199999999997e-200 23342500.0 30324.6 27753.2 42208.0 58905.0 44502.0 40653.0 31688.0 45332.0 32428.0 39536.0 True False 39967.192009136175 36723.87915659393 41648.2943417827 45325.36232317789 38323.665460435404 38110.9614834527 34508.170612209906 38326.981025728885 34142.07787692589 38151.85667382183 1.0475818346361097 0.9625712182388304 1.091645282111787 1.188025073345335 1.0045032876927182 0.9989280943593714 0.9044951837399813 1.0045901921210356 0.8948995108894064 1.0 15.21946564759055 -6.709365843796647 2.7560621606914504 0.9538603113330393 1.0673183281775553 0.40476427375314006 0.06300094050796784 0.28796045937404596 4.465263694018643 0.024067661793835293 0.023029639393755973 1.9526938398747306e-07 6.709365843796647 0.11345801684451606 METVSNASSSSNPS(ph)SPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 METVSNASSSSNPSSPGR 18 0 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 METVSNASSSSNPS(0.5)S(0.5)PGR;METVSNAS(0.001)S(0.001)S(0.001)SNPS(0.498)S(0.498)PGR;METVSNASSSSNPS(0.603)S(0.396)PGR 205.98 3.1457000000000004e-20 164870000.0 68361.8 69567.3 80047.6 87380.7 94375.1 87239.4 91480.7 90467.3 84913.8 73158.4 True False 79934.10253290422 76473.48178973103 81956.23836621366 82485.04267105152 75882.97663232381 82664.41228781357 82814.98583308663 88092.62923302752 86155.50368387326 86421.4387984244 0.9249337160348405 0.8848901713856362 0.9483322599774612 0.9544511618632685 0.8780573164179637 0.9565266840861792 0.9582690011242497 1.019337683540552 0.9969228108412842 1.0 16.399101629570737 -7.394963434411012 1.8281823451118335 1.0059880496987605 0.9207352850387635 0.6723161178994459 0.025368194635651556 0.2123698038539124 1.3835751145659312 0.014581219027489212 0.008136828022311743 4.027509426666881e-08 7.394963434411012 -0.0852527646599971 METVSNASSSSNPS(ph)SPGR ddPTM_PC-9_Lapatinib_30min_R1 5 METVSNASSSSNPSSPGR 18 0 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 METVSNASSSSNPS(0.5)S(0.5)PGR;METVSNAS(0.001)S(0.001)S(0.014)S(0.014)NPS(0.485)S(0.485)PGR;METVSNASSSSNPS(0.955)S(0.045)PGR;METVSNASSSS(0.001)NPS(0.5)S(0.5)PGR;METVSNASSSSNPS(0.741)S(0.258)PGR 204.71 3.7265e-20 127179600.0 84907.2 68748.40000000001 89984.9 67051.8 74491.5 80874.0 76014.2 82542.8 84274.0 58051.3 True False 83696.40775792646 68589.21730368916 82586.68887375883 71983.01305024776 70110.05642592387 77415.20754650196 79949.84333566294 86378.03982530611 74782.17467543787 68085.38985650497 1.2292858707914116 1.0073999348207603 1.212986942541071 1.0572461023129531 1.0297371664271298 1.1370311267903477 1.1742584349471037 1.268672177795475 1.0983586175102598 1.0 16.0550576294326 -6.9909295582295945 24.929148675911197 1.1574163992790065 1.1027184664531149 0.0 0.09251341521894556 551.1965347718457 1514897.332739163 0.031264400763993956 0.02752970187533058 1.0211050916543775e-07 6.9909295582295945 -0.05469793282589164 METVSNASSSSNPSS(ph)PGR ddPTM_PC-9_AZD4547_30min_R2 14 METVSNASSSSNPSSPGR 18 0 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 METVSNASSSSNPS(0.003)S(0.997)PGR;METVSNASSSSNPS(0.046)S(0.954)PGR;METVSNASSSSNPS(0.004)S(0.996)PGR;METVSNASSS(0.001)S(0.001)NPS(0.012)S(0.987)PGR;METVSNASSSSNPS(0.161)S(0.838)PGR;METVSNASSSSNPS(0.233)S(0.767)PGR;METVSNASSSSNPS(0.014)S(0.986)PGR;METVSNASSSSNPS(0.013)S(0.987)PGR;METVSNASSSSNPS(0.008)S(0.992)PGR;METVSNASSSSNPS(0.04)S(0.96)PGR;METVSNASSSSNPS(0.014)S(0.986)PGR;METVSNASSSSNPS(0.006)S(0.994)PGR;METVSNASSSSNPS(0.002)S(0.998)PGR;METVSNASSSSNPS(0.089)S(0.911)PGR 380.03 0.0 474690300.0 293997.9 273484.6 406173.4 532303.5 428896.3 368109.5 314324.1 411498.3 299123.4 369854.6 True False 387483.1166637909 361883.14866715966 400787.27532701456 409589.15208209417 369351.45203403226 345091.5547731542 342298.33597353403 347910.69302522915 314934.45225147606 356906.10302897886 1.0856724314191102 1.0139449720695213 1.1229487866013679 1.1476103899765415 1.0348700930004633 0.966897320736302 0.9590711200187609 0.9747961440630806 0.882401420369954 1.0 18.44518504585558 -6.641320678718462 3.130228464767694 0.9539802627786318 1.0894923133371914 0.6918772898666984 0.042762895208171274 0.15068451410918218 2.9458037554726046 0.015556049655476736 0.015457958142330796 2.2839117629145453e-07 6.641320678718462 0.13551205055855964 METVSNASSSSNPSS(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 METVSNASSSSNPSSPGR 18 0 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 METVSNASSSSNPS(0.022)S(0.978)PGR;METVSNASSSSNPS(0.23)S(0.77)PGR;METVSNASSSSNPS(0.06)S(0.94)PGR;METVSNASSSSNPS(0.227)S(0.773)PGR;METVSNASSS(0.001)S(0.002)NPS(0.017)S(0.98)PGR;METVSNASSSSNPS(0.403)S(0.597)PGR;METVSNASSSS(0.001)NPS(0.092)S(0.907)PGR;METVSNASSSSNPS(0.002)S(0.998)PGR 300.25 1.7340999999999993e-121 289864500.0 161284.69999999998 159126.9 173794.5 214745.6 209867.9 193727.0 204779.7 187640.7 177600.4 163096.1 True False 188587.01419197084 174923.96699895497 177938.41999931127 202714.1002466285 168745.79154432597 183567.61508310726 185381.4843393609 182715.33044675525 180197.4698630531 192664.13186198272 0.9788382111885123 0.9079218083221835 0.923567963998507 1.0521631519448842 0.8758547318252733 0.9527856239199113 0.962200294096055 0.9483619430400547 0.935293290565053 1.0 17.555728485606643 -11.117850710150252 3.0863579509309806 1.0029205155300518 0.9480534286104502 0.10829634674535826 0.04426592127834344 228498609.5586292 364322592.434906 5734289.459823004 0.010649830720391688 7.623410216842387e-12 11.117850710150252 -0.054867086919601626 METVSNASSSSNPSS(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 9 METVSNASSSSNPSSPGR 18 0 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 METVS(0.001)NAS(0.034)S(0.034)S(0.002)S(0.001)NPS(0.079)S(0.849)PGR;METVS(0.003)NAS(0.127)S(0.127)S(0.127)S(0.127)NPS(0.029)S(0.459)PGR;METVSNASSSSNPS(0.054)S(0.946)PGR;METVSNASSSSNPS(0.043)S(0.957)PGR;METVSNASSSSNPS(0.038)S(0.962)PGR;METVSNASSSSNPSS(1)PGR;METVSNASSSSNPSS(1)PGR;METVSNASSSSNPS(0.022)S(0.978)PGR;METVSNASSSSNPS(0.002)S(0.998)PGR 408.66 0.0 253756100.0 316886.0 288635.0 328444.0 262325.9 264075.4 284789.0 274941.0 270354.3 312858.0 209316.5 True False 312367.1475302242 287966.68339118134 301440.60215050366 281618.2217795493 248543.00416421186 272609.2383455838 289176.0996833553 282915.94775489566 277620.63749920664 245496.57812829598 1.2723890080740017 1.172996730083507 1.2278810745499331 1.1471370555412639 1.0124092403207503 1.1104400738454236 1.1779231380252986 1.1524231820740263 1.1308533895495794 1.0 17.905343390008376 -1.5228804883916898 0.432222947422598 1.1033410450680272 4.471103974105178 0.44866668681893873 0.059779414596522494 87.70642939484593 1.0973908766225868 0.04149072554250917 257.61279603139866 0.02999987959037519 1.5228804883916898 3.367762929037151 MEVDRS(ph)PGLPMSDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MEVDRSPGLPMSDLK 15 1 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;H0Y2S9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 MEVDRS(0.998)PGLPMS(0.002)DLK 77.191 0.042524 0.0 27546.0 20502.0 36738.0 43674.0 49351.0 48724.0 42459.0 48729.0 42375.0 36356.0 True False 32208.993741700495 22537.303067002304 37613.973249640854 41227.08737301844 39681.02581911776 46168.82766630015 38436.976143460124 47449.91538264325 42994.6542093761 42947.05500606233 0.7499697880833489 0.5247694647239719 0.8758219450514438 0.9599514417740378 0.923952196804099 1.0750173128234997 0.8949851424744824 1.104846778805795 1.001108322871197 1.0 15.390271584863845 -5.472134251049736 3.480883322400758 0.9932276443865783 0.6387136972488235 0.7602401905199143 0.07890575438001184 0.10237242075803996 2.473730576818718 0.020664842630951235 0.04505958904827489 3.3718306101332365e-06 5.472134251049736 -0.35451394713775475 MEVDRS(ph)PGLPMSDLK ddPTM_PC-9_Lapatinib_30min_R1 1 MEVDRSPGLPMSDLK 15 1 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;H0Y2S9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 MEVDRS(1)PGLPMSDLK 74.789 0.023814 20557000.0 99237.0 75119.0 93828.0 82056.0 94117.0 92562.0 98293.0 86027.0 102030.0 80358.0 True False 97821.86218216285 74945.06657079776 86113.82402655415 88090.67197079175 88581.22310114144 88603.33903256069 103382.13058865732 90024.12847700393 90538.30697646862 94247.77322969557 1.0379222641553207 0.7951919074856624 0.9136961126570302 0.9346711222142293 0.939876031715424 0.9401106890517342 1.096918548268509 0.9551857342836314 0.9606413379742519 1.0 16.524170912111906 -7.0197951275454695 24.05702530004054 1.0021751389352385 0.9193808884585485 0.24592853521219582 0.06563171884342309 657.9504330652907 799605.5214429172 0.02439705399234607 0.01918666750348354 9.554431969284664e-08 7.0197951275454695 -0.08279425047668998 MEVEELS(ph)PLALGR ddPTM_PC-9_AZD4547_30min_R2 1 MEVEELSPLALGR 13 0 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4;P30305-3 G8JLH2 CDC25B M-phase inducer phosphatase 2 1 MEVEELS(1)PLALGR 81.494 0.010190000000000001 4653100.0 21213.0 24590.0 28871.0 32308.0 24054.0 27227.0 22146.0 29551.0 22564.0 22043.0 True False 27958.292742189704 32538.236616341354 28488.15167602371 24859.88975362416 20714.517302263117 25524.49138587478 24116.951097513298 24984.571964425006 23756.686974681023 21271.281279367013 1.3143680615661382 1.5296792040403888 1.339277653370933 1.168706737837089 0.9738255552267107 1.1999508186953152 1.1337798969781179 1.174568265836429 1.1168432527722172 1.0 14.376619316454779 -5.722431833600043 3.189907896853406 1.1124739467033133 1.4236913460987126 0.7196518142789357 0.08287789390239439 0.1212534177297535 2.5193939521547795 0.022875826166786403 0.04085750904021831 1.8948209000904255e-06 5.722431833600043 0.3112173993953993 MEVEELS(ph)PLALGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MEVEELSPLALGR 13 0 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4;P30305-3 G8JLH2 CDC25B M-phase inducer phosphatase 2 1 MEVEELS(1)PLALGR 62.162 0.04451 3711300.0 14299.0 15398.0 21176.0 14668.0 22221.0 19342.0 20326.0 19866.0 18817.0 12999.0 True False 16719.53828187668 16926.611678163168 21680.916150427227 13846.199514297628 17866.954564783195 18327.671470355006 18400.574132503596 19344.53854976691 19092.163026733444 15355.615799972622 1.088822389129226 1.1023075791068795 1.4119209827108257 0.9017026535869903 1.1635452981843326 1.1935484521817539 1.1982960743610427 1.2597696374899794 1.2433342482277712 1.0 13.906478748831823 -6.521894900733017 24.788964203244515 1.194444728640004 1.1308586039305257 0.0270882213716801 0.13363107132369517 120.71743587776676 3041751.4216395263 0.04315417052331106 0.0436757823638594 3.006803861140852e-07 6.521894900733017 -0.06358612470947822 MEVEELS(ph)PLALGR ddPTM_PC-9_Lapatinib_30min_R1 1 MEVEELSPLALGR 13 0 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4;P30305-3 G8JLH2 CDC25B M-phase inducer phosphatase 2 1 MEVEELS(1)PLALGR 67.234 0.03135 2452000.0 13146.0 15421.0 14396.0 12802.0 17130.0 17629.0 20009.0 19993.0 20384.0 17467.0 True False 12958.535629318849 15385.293621963408 13212.416450167018 13743.50178622008 16122.447078875783 16875.04876520616 21044.96811521109 20921.947768034872 18088.139266964004 20486.147676685476 0.6325511186305894 0.7510096024287104 0.6449439230199233 0.6708680423045593 0.7869926222012029 0.8237297236908542 1.0272779659380074 1.021272915641693 0.882944883168515 1.0 14.32236109741441 -6.852813417320917 1.6709918061391327 0.9847123386385377 0.6807004603419831 0.8621327579283256 0.05425995937607783 0.12541183650340068 0.7220063802699944 0.02390404992616942 0.020272199384489018 1.4034165143674433e-07 6.852813417320917 -0.3040118782965546 MEVGPFST(ph)GQESPTAENAR ddPTM_PC-9_AZD4547_30min_R2 1 MEVGPFSTGQESPTAENAR 19 0 Q9Y4W2-3;Q9Y4W2-2;Q9Y4W2 Q9Y4W2-3 LAS1L Ribosomal biogenesis protein LAS1L 1 MEVGPFS(0.063)T(0.529)GQES(0.32)PT(0.087)AENAR 119.48 0.00019059 9436800.0 25746.0 22354.0 25727.0 19060.0 22059.0 32159.0 29732.0 35390.0 28172.0 22008.0 True False 33932.692449932394 29579.493343704533 25385.843170276818 14666.011474064531 18996.48861605645 30148.09264620951 32378.090401484027 29921.288681296763 29661.11440572211 21237.506618713844 1.5977719540782598 1.3927950147236203 1.1953306772795818 0.6905712491287131 0.8944782905596518 1.4195683696523926 1.5245711741393144 1.4088889632143085 1.3966382654160372 1.0 14.374326776577975 -6.811220051018149 24.999937385499354 1.386404193382715 1.143973155043783 0.11118336510006199 0.26616029603044455 227.58177241810515 114290.18244166985 0.10263577416869284 0.09051637606610051 1.544471678771329e-07 6.811220051018149 -0.24243103833893187 MEVGPFSTGQES(ph)PTAENAR ddPTM_PC-9_AZD4547_30min_R2 1 MEVGPFSTGQESPTAENAR 19 0 Q9Y4W2-3;Q9Y4W2-2;Q9Y4W2 Q9Y4W2-3 LAS1L Ribosomal biogenesis protein LAS1L 1 MEVGPFST(0.001)GQES(0.584)PT(0.414)AENAR 139.78 0.00014292 9621100.0 19939.0 18700.0 21061.0 12067.0 17404.0 24967.0 28576.0 28160.0 24633.0 20203.0 True False 26279.187243035907 24744.409301569045 20781.717378987058 9285.139583291531 14987.755014907587 23405.8095431423 31119.208640952755 23808.51905242489 25935.050090733803 19495.69911931461 1.3479479285254674 1.269224004234579 1.0659642032738583 0.47626604855081284 0.768772380163533 1.2005627189821522 1.5962089100012116 1.2212190446064857 1.3302959761540254 1.0 14.250868270519078 -6.986879026005744 20.931333792356035 1.3186544071793245 0.9782649697015405 0.22187983542757606 0.2670412284217138 50.251944200745974 80161.69293668824 0.10329376534428317 0.09097639599744445 1.0306731774783097e-07 6.986879026005744 -0.34038943747778394 MEVGPFSTGQES(ph)PTAENAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MEVGPFSTGQESPTAENAR 19 0 Q9Y4W2-3;Q9Y4W2-2;Q9Y4W2 Q9Y4W2-3 LAS1L Ribosomal biogenesis protein LAS1L 1 MEVGPFS(0.001)T(0.005)GQES(0.979)PT(0.016)AENAR;MEVGPFST(0.001)GQES(0.91)PT(0.089)AENAR 173.03 3.0226e-28 7056600.0 32015.0 65234.0 48722.0 29909.0 44687.0 29853.0 41681.0 17901.3 28485.0 39951.0 True False 37434.50717492705 71710.00040351311 49883.71725921397 28233.295696286288 35930.9031383136 28287.456126797042 37732.67393569235 17431.40984299518 28901.539236674405 47193.800048058016 0.7932081573598023 1.5194792606335992 1.0569972582927583 0.5982416263902458 0.7613479546407522 0.5993892438835522 0.7995260796390354 0.36935804756651436 0.6124011884451691 1.0 15.526309721606204 -5.669508396641044 4.697165033209987 0.6564889042612281 1.1842621359888432 0.44975093958311185 0.22568230890771276 0.15977222595066076 6.079436335748759 0.05882036243242094 0.10381643450983848 2.140383544237881e-06 5.669508396641044 0.5277732317276151 MEVGPFSTGQES(ph)PTAENAR ddPTM_PC-9_Lapatinib_30min_R1 2 MEVGPFSTGQESPTAENAR 19 0 Q9Y4W2-3;Q9Y4W2-2;Q9Y4W2 Q9Y4W2-3 LAS1L Ribosomal biogenesis protein LAS1L 1 MEVGPFS(0.011)T(0.003)GQES(0.979)PT(0.007)AENAR;MEVGPFST(0.005)GQES(0.987)PT(0.007)AENAR 227.88 2.1920000000000002e-35 14333900.0 103378.0 89111.0 76148.0 54971.0 73555.0 76426.0 74256.0 76440.0 78711.0 64619.0 True False 101903.81076279675 88904.66895446373 69887.40537978052 59013.75071788032 69228.63951469405 73157.4381377076 78100.61234260163 79991.68145793962 69845.7383164249 75788.30805059477 1.3445848493512718 1.1730657569913387 0.9221396700547144 0.7786656310955499 0.9134474867611292 0.9652865992056341 1.030510039760529 1.0554620299022741 0.9215898878465169 1.0 16.20968767888942 -5.045052169175013 2.9611263116863005 0.9470037773623023 1.3351295772894183 0.7555818760847944 0.07357823510692962 0.1457036100288124 2.3927844126645406 0.022123943979490437 0.09913264260923474 9.014628438109205e-06 5.045052169175013 0.38812579992711593 MEVGPFSTGQESPT(ph)AENAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MEVGPFSTGQESPTAENAR 19 0 Q9Y4W2-3;Q9Y4W2-2;Q9Y4W2 Q9Y4W2-3 LAS1L Ribosomal biogenesis protein LAS1L 1 MEVGPFS(0.003)T(0.01)GQES(0.059)PT(0.929)AENAR 169.58 6.9818e-28 0.0 10661.0 18881.0 12044.0 11764.0 12189.0 9920.7 10222.0 5584.9 7063.4 7115.9 True False 12465.696735651956 20755.380899818083 12331.17463712435 11104.901219402595 9800.652949468631 9400.441027605779 9253.698159128791 5438.302292690688 7166.688862360052 8405.95634056659 1.4829599667908488 2.4691278492197237 1.4669567789229305 1.3210752910779555 1.165917660334652 1.118307143975977 1.100850133431107 0.6469581892123089 0.8525726963122666 1.0 13.037196248002838 -5.908773159375589 0.9280736121133882 0.8997062163355793 2.018839285182375 0.6590348232892516 0.27524212317352265 0.37722447046068863 0.6389215535949885 0.11698777984840138 0.2972236314941782 1.2337490765843137e-06 5.908773159375589 1.1191330688467955 MEVKDANSALLS(ph)NY(ph)ETLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MEVKDANSALLSNYETLK 18 1 O75575-2 O75575-2 2 MEVKDANSALLS(0.923)NY(0.917)ET(0.16)LK 51.606 0.027149 11019000.0 65206.0 86803.0 88912.0 81796.0 92896.0 69344.0 88899.0 62032.0 66716.0 63471.0 True False 76244.08792279541 95420.22817895828 91031.9992806378 77213.23530621004 74693.6956595159 65707.47856686474 80477.84314697605 60403.7257283369 67691.59528572836 74977.78986384034 1.0168889755386852 1.2726465844384238 1.2141195338773243 1.029814768432482 0.9962109552063303 0.8763592349973174 1.0733557669961171 0.8056215825783883 0.9028219611255051 1.0 16.194175679175565 -6.0459355992000186 2.227577592081162 0.9328286433016145 1.1773427271225498 0.5371687635543043 0.0927175336500719 0.2230858873496726 2.2021313506469338 0.02915586022688851 0.043706658560368566 8.996309764072629e-07 6.0459355992000186 0.2445140838209353 MEVY(ph)AS(ph)EKEQHGDLCRPGEHVTS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 MEVYASEKEQHGDLCRPGEHVTSR 24 2 G5E953 G5E953 MTMR3 3 MEVY(1)AS(1)EKEQHGDLCRPGEHVT(0.166)S(0.834)R 51.323 0.032166 0.0 968.13 1064.0 1191.1 2108.3 2634.5 2731.5 1196.6 2130.4 1098.1 893.77 True False 1275.975201645035 1407.9171923459608 1175.3052357490849 1622.2640079102953 2268.7451497801694 2560.6988731963456 1303.0950818786414 1801.1956317218035 1156.1433241844181 862.4793843424156 1.479426899714111 1.6324067773740538 1.3627053087711523 1.8809307646781215 2.6304920337428586 2.9689971953923417 1.5108709906987128 2.088392678620484 1.340488068669493 1.0 9.752346162538496 -5.903201816052604 5.687823058451645 2.029860244804872 1.5110373613503356 0.09117437800684947 0.5560181796621321 0.4152878788610591 20.120817122824803 0.16128522158991276 0.24223478366314713 1.249678171526488e-06 5.903201816052604 -0.5188228834545365 MEYAMKS(ph)LSLLY(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 MEYAMKSLSLLYPK 14 1 A0A0C4DG75;A0A0A0MRY9;Q96AQ7-3;Q96AQ7;Q96AQ7-4 A0A0C4DG75 CIDEC Cell death activator CIDE-3 2 MEY(0.567)AMKS(0.434)LS(0.105)LLY(0.894)PK 60.628 0.025378 8122200.0 0.0 1654.6 24116.0 24951.0 21478.0 17932.0 7400.6 29188.0 8626.6 15497.0 True False 0.0 2189.4170925334856 23796.206082885514 19198.93243910725 18496.15043726645 16810.70920525606 8059.239063138126 24677.665273514835 9082.584464447053 14954.454746919684 0.0 0.1464056784139496 1.5912453169037843 1.2838269775808338 1.2368321513745784 1.1241271908438337 0.5389189508763712 1.6501882342850338 0.6073497575241171 1.0 13.86828768898662 -5.189072550028528 7.210899636659889 1.139603442294521 0.05631444385714322 0.6044426424743543 0.3417339193404687 0.17111232545328298 14.75653820084112 0.08387383233086718 0.22523152538005567 6.470345179121365e-06 5.189072550028528 -1.0832889984373777 MFGGPGTASR ddPTM_PC-9_Lapatinib_30min_R1 1 MFGGPGTASR 10 0 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 0 93.14299999999999 0.026851 0.0 18213.0 17231.0 16304.0 17542.0 17563.0 19568.0 11962.0 11798.0 14973.0 17445.0 False True 17953.279280144852 17191.102678169493 14963.548055260011 18832.097198396536 16529.97887018653 18731.122255235936 12581.333829484482 12346.178150716518 13286.583067320062 20460.345005998654 0.8774670844935035 0.8402156793118264 0.7313438776752266 0.9204193376443681 0.8079032325867525 0.9154841841495959 0.6149130831271824 0.6034198419966433 0.6493821616118713 1.0 14.32054285181973 -7.261881808184981 24.999105239557224 0.6838804248599814 0.8444719235382343 0.21209989368522608 0.11764561178134154 49.63888151541099 2804687.0290610525 0.04463660746430732 0.03217983357596976 5.4716485174823085e-08 7.261881808184981 0.16059149867825295 MFPTGFSS(ph)PSPSAAAAAQEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MFPTGFSSPSPSAAAAAQEVR 21 0 A0A669KAX4;Q13620-1;A0A669KAU9 A0A669KAX4 CUL4B Cullin-4B 1 MFPT(0.048)GFS(0.051)S(0.848)PS(0.049)PS(0.003)AAAAAQEVR 143.69 6.3678e-11 0.0 2683.8 8285.8 7105.2 6500.2 8977.9 8116.6 8870.7 9319.4 5011.4 4687.4 True False 3138.114332533791 9108.35946505548 7274.614914621051 6136.014867932736 7218.744943394401 7690.951207542318 8030.403077693578 9074.775624720509 5084.68224436265 5537.188514562016 0.566734241444191 1.6449429960894042 1.313774110361215 1.1081462825034567 1.3036841574763314 1.3889632233607747 1.4502672351816743 1.6388778530575838 0.9182786952242389 1.0 12.434937924174262 -4.74605968944127 24.999729929060464 1.3282661233666146 0.566732176866117 0.4754561826631305 0.23247535108173617 729.8205182248422 1186260.2258543393 0.05563209595191799 1.3244319361357935 1.794486975561394e-05 4.74605968944127 -0.7615339465004977 MFPTGFSS(ph)PSPSAAAAAQEVR ddPTM_PC-9_Lapatinib_30min_R1 2 MFPTGFSSPSPSAAAAAQEVR 21 0 A0A669KAX4;Q13620-1;A0A669KAU9 A0A669KAX4 CUL4B Cullin-4B 1 MFPT(0.001)GFS(0.031)S(0.755)PS(0.195)PS(0.017)AAAAAQEVR;MFPTGFS(0.184)S(0.602)PS(0.199)PS(0.015)AAAAAQEVR 137.89 2.828e-10 0.0 24479.0 16225.3 20571.6 18629.9 17112.7 18523.4 13716.2 12111.6 16556.0 12127.900000000001 True False 24129.924971101176 16187.73131472946 18880.28245667239 20000.004993524555 16106.164630862671 17731.197362154406 14426.357722117962 12674.3491515696 14691.28893759106 14224.191355589048 1.6964004749289254 1.1380422907745043 1.3273360843288884 1.4060556761046414 1.132307927264642 1.2465522235249855 1.0142128548101597 0.8910418058028673 1.0328382521245032 1.0 13.796059017287476 -6.690179886789616 0.6613847080419643 0.9431200579718693 1.4265768623366526 0.6096302580533934 0.14141139575880196 0.5369697957690346 0.5190012070172468 0.10452146888021564 0.11896529407187244 2.0408924224604838e-07 6.690179886789616 0.48345680436478333 MFPTPPSLEQHPAFS(ph)PVMNYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MFPTPPSLEQHPAFSPVMNYK 21 0 F8VRB8;H0YHC1;A0A3B3IS46;A0A3B3IRX3;Q71F56 F8VRB8 MED13L Mediator of RNA polymerase II transcription subunit 13-like 1 MFPT(0.001)PPS(0.006)LEQHPAFS(0.966)PVMNY(0.027)K 45.236999999999995 0.038077 6412600.0 12308.0 15031.0 16329.0 21244.0 22974.0 20096.0 17162.0 16771.0 16893.0 13584.0 True False 14391.501305919173 16523.17834358168 16718.34528807735 20053.76755397728 18472.409620238926 19042.130383013882 15536.291117879899 16330.779020343338 17140.02816658384 16046.671669115165 0.8968527307515316 1.029695047315241 1.0418575037124334 1.249715079082382 1.1511676689810106 1.186671652269426 0.9681939930124208 1.0177050641457936 1.0681360297022247 1.0 13.969986470391836 -10.70350777168085 14.51966300368253 1.0000003252545069 1.0727938328069442 0.03827982094072402 0.09908540283740579 0.0 0.0 0.1034045809657822 0.02507929467615609 1.979211603015186e-11 10.70350777168085 0.0727935075524373 MFS(ph)GKLKPTMAFMSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MFSGKLKPTMAFMSGK 16 2 Q6YN16-2;Q6YN16 Q6YN16-2 HSDL2 Hydroxysteroid dehydrogenase-like protein 2 1 MFS(0.958)GKLKPT(0.041)MAFMS(0.002)GK 41.553999999999995 0.038675 4276200.0 37002.0 52835.0 35404.0 62124.0 36362.0 43865.0 50026.0 50849.0 56903.0 51900.0 True False 43265.70777718731 58080.10962564949 36248.16563041767 58643.39368872545 29237.127126801057 41564.6421800808 45287.175123124296 49514.267628968926 57735.09872510039 61309.059159826036 0.7056984460387546 0.9473332395175235 0.5912366969442909 0.9565208550313669 0.4768810274935561 0.6779526998078099 0.7386702021485204 0.8076174762344767 0.9417058346074318 1.0 15.903812644971403 -8.208918069371702 1.9729027550885905 0.9971560394530784 0.7279893783312362 0.336858227848866 0.13612715424016533 0.38518407291674134 2.701407609975502 0.12259270770960315 0.036575708741600814 6.181330013169381e-09 8.208918069371702 -0.2691666611218422 MFS(ph)PMEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MFSPMEEK 8 0 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 MFS(1)PMEEK;MFS(1)PMEEK 69.27600000000001 0.024692 39790000.0 206007.0 264750.0 206500.0 243190.0 253660.0 198007.0 238600.0 183359.0 168295.0 166835.0 True False 240879.91627628292 291032.63032820454 211423.74315561142 229564.85273261735 203957.14391354594 187623.16434859796 215998.080685593 178546.02053491928 170755.99599214023 197080.86483486625 1.2222389853937154 1.4767168318043475 1.0727766154911236 1.164825681706691 1.0348906479806719 0.9520110666543254 1.0959870754909538 0.905953100441906 0.8664260537684184 1.0 17.5884281820816 -5.745455791474443 0.775622884662428 0.9505342658615653 1.3835655344284574 0.6531916020317048 0.09956400872016623 0.5584501471452941 0.5845491451622786 0.04640041417424489 0.16823366918532054 1.7969839928580093e-06 5.745455791474443 0.4330312685668921 MFVSSSGLPPS(ph)PVPSPR ddPTM_PC-9_AZD4547_30min_R2 7 MFVSSSGLPPSPVPSPR 17 0 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 MFVSSSGLPPS(0.995)PVPS(0.005)PR;MFVSSSGLPPS(0.997)PVPS(0.003)PR;MFVSSSGLPPS(1)PVPSPR;MFVS(0.002)S(0.02)S(0.016)GLPPS(0.962)PVPSPR;MFVS(0.002)S(0.014)S(0.004)GLPPS(0.975)PVPS(0.005)PR;MFVSS(0.003)S(0.002)GLPPS(0.995)PVPSPR;MFVS(0.001)S(0.003)S(0.003)GLPPS(0.99)PVPS(0.003)PR 177.66 3.9122e-06 49028700.0 175582.1 185993.0 227825.0 327253.0 279957.0 243258.0 209158.0 268673.0 227972.0 226530.0 True False 231413.55546544213 246111.59995864882 224803.89164178935 251809.87685844873 241089.80295957785 228047.03880505072 227772.65680726498 227155.76134134043 240022.134505938 218599.2536503662 1.0586200620591846 1.1258574576484448 1.028383619284204 1.15192468708608 1.1028848403351992 1.043219658790764 1.0419644761073656 1.0391424378084095 1.0980007044755795 1.0 17.737928949752423 -6.764621920571355 24.952302738183214 1.0467555395636656 1.094954322910634 0.2862152556941202 0.03862760795586491 109.46905709530053 858265.2611579207 0.012851386443437035 0.011792795021089595 1.7194045807486372e-07 6.764621920571355 0.048198783346968366 MFVSSSGLPPS(ph)PVPSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 MFVSSSGLPPSPVPSPR 17 0 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 MFVS(0.001)S(0.003)S(0.001)GLPPS(0.963)PVPS(0.033)PR;MFVSS(0.001)S(0.002)GLPPS(0.986)PVPS(0.011)PR;MFVS(0.042)S(0.115)S(0.091)GLPPS(0.746)PVPS(0.006)PR;MFVSS(0.001)S(0.001)GLPPS(0.685)PVPS(0.312)PR;MFVSS(0.001)SGLPPS(0.98)PVPS(0.019)PR;MFVSSSGLPPS(1)PVPSPR 119.96 8.0923e-05 75003500.0 243892.0 261418.0 255839.0 283227.0 339457.0 284075.0 298572.0 279002.0 262370.0 227388.0 True False 285178.0985134256 287369.8513886258 261939.17203481073 267358.709424323 272942.837662464 269177.60691454343 270289.0986859126 271678.49312705494 266206.66489472537 268611.6443975826 1.0616743706438962 1.0698339308152942 0.9751594076357475 0.9953355150478692 1.0161243689736348 1.0021069917435266 1.0062449053245328 1.0114174079696 0.9910466297607801 1.0 18.035162321832523 -5.249420085728065 24.999862208648945 1.0008405310761614 1.0657541620037787 0.8536196343732989 0.01093626770165247 268.59123919769826 558661.4580702941 0.002872113532941218 0.007470797782775749 5.630927222221283e-06 5.249420085728065 0.06491363092761726 MFVSSSGLPPS(ph)PVPSPR ddPTM_PC-9_Lapatinib_30min_R1 5 MFVSSSGLPPSPVPSPR 17 0 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 MFVSSSGLPPS(1)PVPSPR;MFVSSSGLPPS(1)PVPSPR;MFVS(0.001)S(0.003)S(0.003)GLPPS(0.993)PVPSPR;MFVSS(0.002)S(0.005)GLPPS(0.986)PVPS(0.008)PR;MFVS(0.236)S(0.131)S(0.019)GLPPS(0.614)PVPSPR 240.34 8.508300000000001e-38 34485200.0 220637.0 187684.0 207685.0 164605.0 190602.4 179121.9 170509.3 174466.3 187998.0 153722.0 True False 217490.67592012996 187249.4292292706 190609.94098728374 176710.6008061834 179391.54157073618 171461.27389054294 179337.43724558767 182572.6412185416 166823.6855332957 180292.64287831 1.2063203048552962 1.0385860800523965 1.0572252863137488 0.9801320674269315 0.9950020073299274 0.9510164760648172 0.9947019156329798 1.0126460974992224 0.9252939158803875 1.0 17.45998100099333 -1.5228789075072866 0.7536824007427186 0.9790420795841883 41.1925593287037 0.833117542767643 0.029832635938869128 139.3169854740099 0.5922613612406123 0.010549524854268815 9516.238932866345 0.029999988793761458 1.5228789075072866 40.21351724911951 MFVSSSGLPPSPVPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 MFVSSSGLPPSPVPSPR 17 0 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 MFVS(0.001)S(0.007)S(0.002)GLPPS(0.02)PVPS(0.971)PR;MFVS(0.001)S(0.001)S(0.001)GLPPS(0.044)PVPS(0.953)PR 76.051 0.007549800000000001 14377300.0 42309.0 42091.0 50801.0 54157.0 58393.0 48702.0 44975.0 57588.0 49498.0 49904.0 True False 55762.38191813057 55696.09261563334 50127.34554721628 41671.940367309166 50286.13988654901 45656.656241042845 48977.687871880225 48689.09784059105 52114.36322783021 48156.87614959541 1.1579318755001733 1.1565553472076961 1.0409177163298502 0.8653372830467383 1.0442151548688337 0.9480817671647589 1.0170445383486884 1.011051831712305 1.082179065476365 1.0 15.555454189635917 -5.344441180808881 4.033380142555425 0.9944099799649708 1.1584859837801245 0.5704533824701797 0.055078270239311874 0.1494128137270385 4.480268071379493 0.014601926476209722 0.03355858431174813 4.5243773462735264e-06 5.344441180808881 0.16407600381515364 MFVSSSGLPPSPVPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MFVSSSGLPPSPVPSPR 17 0 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 MFVSS(0.009)S(0.002)GLPPS(0.217)PVPS(0.772)PR 87.15700000000001 0.0025916999999999997 4315200.0 11749.0 7324.3 12769.0 17786.0 25787.0 25632.0 25532.0 30823.0 30801.0 21268.0 True False 13737.873646672442 8051.408099387616 13073.461386702169 16789.50808299001 20734.222463528396 24287.812797442857 23113.424124327546 30013.928909668026 31251.406355232888 25123.72004260465 0.5468088970652372 0.32047037961472613 0.5203632807773798 0.6682731719076023 0.8252847280724124 0.9667283649179235 0.9199841458642248 1.1946450947061418 1.2439004376038638 1.0 14.61676247792164 -6.403527640441319 0.7883397446363769 1.1417525811154074 0.3955210055184703 0.8842537435459803 0.09748016565102824 0.20528353279654787 0.2810859338234861 0.05811463158173044 0.08408115474892619 3.948865662037072e-07 6.403527640441319 -0.7462315755969371 MFVSSSGLPPSPVPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 MFVSSSGLPPSPVPSPR 17 0 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 MFVSSSGLPPS(0.057)PVPS(0.943)PR 151.31 6.319e-12 0.0 9817.8 9097.6 9895.2 7250.8 9771.9 10991.0 11550.0 12739.0 12311.0 11213.0 True False 9677.79637163598 9076.53506615488 9081.654852576596 7784.048019959738 9197.13605429459 10520.940551272386 12148.00248541596 13330.90044600591 10924.40553942278 13151.152109616676 0.735889623279406 0.6901703356862351 0.6905596389487205 0.591890957923581 0.699340710048457 0.800001434367034 0.9237215404521729 1.01366787752822 0.8306804946339564 1.0 13.68290157222461 -7.0356619841744 2.2086307987242937 0.9461606607854834 0.6762290492359952 0.8235914044765271 0.05688555327423161 0.12474166201185194 1.2124449352656854 0.024765199844092714 0.018982593244352565 9.211662459058019e-08 7.0356619841744 -0.2699316115494882 MGAGLGHGMDR ddPTM_PC-9_AZD4547_30min_R2 1 MGAGLGHGMDR 11 0 A0A087X0X3;P52272-2;P52272;M0R2T0;M0QZM1 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 62.166000000000004 0.032343000000000004 6282800.0 9451.6 7743.5 13285.0 14923.0 13297.0 11799.0 11098.0 13125.0 10955.0 12485.0 False True 12457.012194507155 10246.434942604279 13108.832219735197 11482.73290805167 11450.94107292728 11061.206664778952 12085.700500325223 11096.832832495624 11534.058934924244 12047.903950138238 1.033956798299693 0.8504744879283929 1.088059157342866 0.9530896789661008 0.9504508933934431 0.918102162048863 1.003137188870646 0.9210592048559865 0.9573498413217265 1.0 13.55649455307734 MGATPT(ph)PFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MGATPTPFK 9 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 MGAT(0.087)PT(0.913)PFK 87.75399999999999 0.040669 16037000.0 173540.0 178250.0 193050.0 216050.0 210540.0 168880.0 182890.0 163740.0 165900.0 150860.0 True False 202916.89442876264 195945.4819867896 197653.04414620248 203945.41894355087 169286.1983740358 160023.63550375128 165565.3351910651 159441.99849687045 168325.97364803543 178209.72379289713 1.138640979347336 1.099521832010153 1.1091035883984703 1.1444124069265826 0.949926832111408 0.897951200966562 0.9290477066418303 0.8946874227927247 0.9445386596505368 1.0 17.443216532312704 -6.310783015659377 5.382414122930474 0.9269399246039686 1.1203969730517 0.8996585571692843 0.030522274270862973 0.05516921069036315 3.776415527245205 0.009042661730009068 0.010433243413548053 4.88896563233072e-07 6.310783015659377 0.19345704844773148 MGCGNS(ph)T(ph)AT(ph)S(ph)AGAGQETMEEYMLAYHLK ddPTM_PC-9_AZD4547_30min_R2 1 MGCGNSTATSAGAGQETMEEYMLAYHLK 28 0 F8W1S6 F8W1S6 C12orf75 4 MGCGNS(0.968)T(0.968)AT(0.968)S(0.942)AGAGQET(0.074)MEEY(0.04)MLAY(0.04)HLK 40.141999999999996 0.045223 0.0 833.41 0.0 763.43 1064.7 1054.6 2319.2 676.58 1467.5 1084.0 949.14 True False 1098.4170439951129 0.0 753.3064193836996 819.2498644510227 908.186993721073 2174.1800573739574 736.7943092908666 1240.7315947952238 1141.2980269701386 915.9108974957312 1.1992619009102163 0.0 0.8224669249414739 0.8944645889583829 0.9915669703289078 2.3737899213979934 0.8044388502259311 1.354642245427598 1.2460797552367346 1.0 9.839063445309185 -6.180224280885394 2.2272669457631538 1.35467317245185 0.6256751898770426 0.2623177030062186 0.48182907330216174 0.38709649673377183 3.7677810685553643 0.15560946077193744 0.21167152217047805 6.603523369365895e-07 6.180224280885394 -0.7289979825748073 MGGAGGEGS(ph)DDDTSLT ddPTM_PC-9_AZD4547_30min_R2 2 MGGAGGEGSDDDTSLT 16 0 F5GY11;F5H8H3;Q9Y365 F5GY11 STARD10 PCTP-like protein 1 MGGAGGEGS(0.868)DDDT(0.009)S(0.121)LT(0.001);MGGAGGEGS(1)DDDTSLT 117.03 0.001592 0.0 40247.0 46434.0 50781.0 90953.0 73869.0 54695.0 50277.0 79632.0 50089.0 54342.0 True False 53044.708810394965 61442.88243363943 50107.61076028401 69985.19105984212 63613.56442175418 51274.91300365157 54751.55560054527 67326.70416131744 52736.602281279775 52439.50312041748 1.0115410264011797 1.1716907822819635 0.9555317609555012 1.3345891340567102 1.2130848050882093 0.9777917400534546 1.044089900600671 1.2838928699746504 1.0056655601823699 1.0 15.678366395217703 -8.470115591728936 24.995454860378622 0.9999972778671863 1.1238429244368857 0.1363811707021172 0.12203087234004333 563.3329008540147 266867.7294324862 0.11714890884250008 0.03024771820020165 3.387539814500814e-09 8.470115591728936 0.12384564656969943 MGGAGGEGS(ph)DDDTSLT ddPTM_PC-9_Lapatinib_30min_R1 2 MGGAGGEGSDDDTSLT 16 0 F5GY11;F5H8H3;Q9Y365 F5GY11 STARD10 PCTP-like protein 1 MGGAGGEGS(0.978)DDDT(0.005)S(0.016)LT(0.001);MGGAGGEGS(0.624)DDDT(0.006)S(0.37)LT 120.87 0.00017788 9723500.0 69226.0 68298.0 59060.0 58314.0 56301.0 62242.0 53055.0 59049.0 65932.0 49983.0 True False 68238.8245455065 68139.86017721654 54204.31477819285 62602.60608980139 52989.4858720248 59580.05475318861 55801.92829989128 61792.632108972735 58506.04386526055 58622.49495183895 1.1640382177791615 1.1623500540738934 0.9246333651053945 1.0678939226525974 0.9039104513644136 1.016334340633853 0.9518859329637046 1.0540771449549904 0.998013542639663 1.0 15.839166749454224 -5.247036265935842 24.78181467047066 0.9908695689227542 1.1631941813980207 0.6659494794990581 0.04917426076810626 386.57069479213993 665125.7831516159 0.011673895358636461 0.0305735750074103 5.66192006972266e-06 5.247036265935842 0.17232461247526643 MGLLS(ph)PSGIGGVSPR ddPTM_PC-9_AZD4547_30min_R2 3 MGLLSPSGIGGVSPR 15 0 M0QZ22;Q5PRF9;A0A087WZT0 M0QZ22 SAMD4B Protein Smaug homolog 2 1 MGLLS(0.851)PS(0.149)GIGGVSPR;MGLLS(0.962)PS(0.038)GIGGVSPR;MGLLS(0.977)PS(0.022)GIGGVSPR 87.824 0.0044394 24542400.0 78535.0 76363.0 101882.0 144276.0 114121.0 100427.0 84343.0 114456.0 76999.0 93153.0 True False 103507.49637052148 101045.8463901453 100530.97811148372 111015.39724197985 98277.26902184974 94147.28381420061 91849.36360595866 96769.45513722817 81069.00994342606 89891.74182356644 1.1514683581688643 1.1240837516361781 1.118356103375984 1.234989944458675 1.0932847337049254 1.0473407445923861 1.0217775486677576 1.0765110695836873 0.9018515861283782 1.0 16.45590096383834 -6.759324856230629 2.093575071535093 1.0073669355871953 1.152768731890463 0.6542515713665024 0.05100204591127583 0.2084322459932746 1.87973650981291 0.020075088661860134 0.01849448267329679 1.740504473139823e-07 6.759324856230629 0.14540179630326766 MGLLS(ph)PSGIGGVSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MGLLSPSGIGGVSPR 15 0 M0QZ22;Q5PRF9;A0A087WZT0 M0QZ22 SAMD4B Protein Smaug homolog 2 1 MGLLS(0.992)PS(0.008)GIGGVSPR 108.36 0.00065443 8899000.0 19646.0 19721.0 26126.0 31123.0 52896.0 54097.0 64609.0 57832.0 60862.0 48464.0 True False 22971.679773812826 21678.770548451477 26748.942923406747 29379.2792121274 42531.40851711318 51260.058087674224 58488.76779134731 56313.97127806903 61751.99161040825 57250.13955918709 0.40125107031510276 0.3786675581120505 0.467229305105061 0.5131739317727624 0.7429048879984441 0.8953700110142069 1.0216353748951073 0.9836477554757711 1.0786347786378232 1.0 15.80499158963417 -6.4695196327347855 1.1142975731914382 1.0326716598641972 0.3891124328043828 0.9891209911035621 0.02790144211740543 0.041383863607674376 0.10852530604531671 0.012156456517750333 0.014690526270858777 3.392191544393302e-07 6.4695196327347855 -0.6435592270598144 down MGLLS(ph)PSGIGGVSPR ddPTM_PC-9_Lapatinib_30min_R1 2 MGLLSPSGIGGVSPR 15 0 M0QZ22;Q5PRF9;A0A087WZT0 M0QZ22 SAMD4B Protein Smaug homolog 2 1 MGLLS(0.81)PS(0.19)GIGGVSPR;MGLLS(0.967)PS(0.033)GIGGVSPR 163.64 1.6362e-05 12149100.0 45676.0 44653.0 47198.0 40923.0 67535.0 73837.0 74793.0 70555.0 76580.0 59574.0 True False 45024.651864047475 44549.60872197213 43317.562629548695 43932.61393512611 63562.72407891869 70679.16363245374 78665.41557504042 73833.24287369073 67954.75397684974 69871.28652263478 0.6443942011782158 0.6375953691297827 0.6199622875917131 0.6287649207789262 0.9097116604304627 1.0115623620234508 1.1258618452596658 1.0567036410553636 0.9725705273057456 1.0 16.092412084049204 -6.41369689499873 2.4658151762656626 1.0428244514082998 0.6274371444759916 0.9568971007343687 0.040156856488211386 0.05672233870481501 0.6758246911638017 0.014662959982464354 0.016834961806026016 3.8574748657570517e-07 6.41369689499873 -0.4153873069323082 MGLLSPS(ph)GIGGVSPR ddPTM_PC-9_Lapatinib_30min_R1 1 MGLLSPSGIGGVSPR 15 0 M0QZ22;Q5PRF9;A0A087WZT0 M0QZ22 SAMD4B Protein Smaug homolog 2 1 MGLLS(0.186)PS(0.814)GIGGVSPR 91.712 0.0033634 5709200.0 21545.0 21151.0 20900.0 20189.0 31748.0 35782.0 33077.0 43240.0 39059.0 26991.0 True False 21237.764349130895 21102.02615901357 19181.682676333054 21673.766408529704 29880.645058969538 34251.68727191598 34789.56521299601 45249.088255380804 34659.76411049583 31656.358386753185 0.6708846320749887 0.666596767107737 0.6059345943075928 0.6846576016020604 0.9439065824916012 1.0819844422234248 1.0989755924532978 1.4293838761414701 1.0948752755149322 1.0 14.950207683049046 -6.530351834829455 1.5401392414018074 1.1865797860187326 0.6399130595562662 0.8191042729324699 0.1071764228588283 0.1471513220441706 0.7132424207612573 0.04272067630265837 0.0468060332443267 2.948819332809834e-07 6.530351834829455 -0.5466667264624664 MGLS(ph)MER ddPTM_PC-9_Lapatinib_30min_R1 3 MGLSMER 7 0 A0A087X0X3;P52272-2;P52272;M0QZM1;M0R2I7 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 1 MGLS(1)MER;MGLS(1)MER;MGLS(1)MER 75.043 0.033296 9271600.0 39322.0 29402.2 50280.0 35098.7 41326.9 40787.4 32259.0 40531.7 41531.0 34664.1 True False 38761.26106922835 29334.1210123658 46146.172486412725 37679.97548383087 38896.132993811545 39043.01798207328 33929.21317550074 42414.950750245545 36853.341439181815 40655.743497990115 0.9534018501259134 0.7215246478966982 1.1350468228110018 0.9268057165328595 0.9567192639272343 0.9603321603011254 0.8345490761269214 1.0432708173776823 0.906473188493127 1.0 15.311171557944318 -5.2455567111467305 24.999430244777876 0.9646881588238652 0.8374632837933257 0.24750962529429354 0.09228786526638916 1136.0976604845082 1788219.1660140492 0.02209334030009892 0.05803052592204689 5.681241997847337e-06 5.2455567111467305 -0.12722487503053947 MGMTFSS(ph)AYVPSALCCPSR ddPTM_PC-9_AZD4547_30min_R2 1 MGMTFSSAYVPSALCCPSR 19 0 F5H4C6 F5H4C6 GNS 1 MGMT(0.014)FS(0.081)S(0.331)AY(0.287)VPS(0.287)ALCCPSR 56.215 0.020235 3012900.0 1072.2 0.0 2656.5 1861.3 4636.1 2308.1 997.18 6505.0 2578.0 2166.7 True False 1413.1372968545616 0.0 2621.2730742737344 1432.2060417983375 3992.457539911117 2163.77414212868 1085.9270882063709 5499.801720029257 2714.2678169086903 2090.8444924921523 0.6758691533152676 0.0 1.2536910725241672 0.6849892696186315 1.9094952083941756 1.0348804752808758 0.5193724794482518 2.630421219645009 1.298168193117728 1.0 11.029870049481378 -5.6030517446270265 1.3042733748793385 1.4068751626749407 0.3255377562303009 0.2650625720802423 0.6046045976314316 0.6613183528059545 2.1183225144281037 0.20112433472361774 0.6385240478867904 2.4942975226504964e-06 5.6030517446270265 -1.0813374064446397 MGPSGGEGMEPERRDS(ph)QDGSSYR ddPTM_PC-9_AZD4547_30min_R2 1 MGPSGGEGMEPERRDSQDGSSYR 23 2 Q14847;Q14847-2;C9J9W2;Q14847-3 Q14847 LASP1 LIM and SH3 domain protein 1 1 MGPS(0.001)GGEGMEPERRDS(0.889)QDGS(0.047)S(0.047)Y(0.016)R 46.982 0.023549 299710000.0 198210.0 168390.0 192580.0 221100.0 285230.0 112820.0 144750.0 194200.0 158990.0 168930.0 True False 261236.65697588338 222818.77445407573 190026.26337046348 170128.810960948 245630.73792818328 105765.34756507845 157632.46958209385 164190.85227204964 167393.8868154818 163015.81211829008 1.6025234213863915 1.3668537521525241 1.1656922166088628 1.043633796931898 1.506790873451864 0.6488042245149284 0.966976562173675 1.0072081360604879 1.0268567486816238 1.0 17.314652383422313 -1.5228787452840358 0.40645591124166014 0.9589653271310605 12.126536915915302 0.514284868240988 0.18839109492099992 60.76015804976013 0.7975063771166884 0.133771724489427 546.11697254496 0.029999999999744537 1.5228787452840358 11.167571588784241 MGPSGGEGMEPERRDS(ph)QDGSSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MGPSGGEGMEPERRDSQDGSSYR 23 2 Q14847;Q14847-2;C9J9W2;Q14847-3 Q14847 LASP1 LIM and SH3 domain protein 1 1 MGPSGGEGMEPERRDS(0.933)QDGS(0.023)S(0.023)Y(0.021)R 52.03 0.010533 60863000.0 21246.0 16407.0 16677.0 22530.0 17857.0 16005.0 13548.0 20910.0 17125.0 16231.0 True False 24842.528172372342 18035.77852991447 17074.642927874702 21267.71714324552 14358.049037547074 15165.669624807766 12264.635360974058 20361.134655976348 17375.420727682973 19173.5518154747 1.2956664686572203 0.940659232232499 0.8905310342183966 1.1092215645762957 0.7488465974237959 0.7909681925791011 0.6396642353492088 1.0619385939512347 0.9062181537830418 1.0 14.226829994172924 -2.0451134447344073 1.0823895206579057 0.8754362440860731 199.99927637194492 0.43287343588418026 0.13599630095026033 737.3777316020812 2.4285446981825096 0.0429789705856312 362576.32288335287 0.009013356634167113 2.0451134447344073 199.12384012785884 MGPSGGEGMEPERRDS(ph)QDGSSYR ddPTM_PC-9_Lapatinib_30min_R1 3 MGPSGGEGMEPERRDSQDGSSYR 23 2 Q14847;Q14847-2;C9J9W2;Q14847-3 Q14847 LASP1 LIM and SH3 domain protein 1 1 MGPSGGEGMEPERRDS(0.975)QDGS(0.011)S(0.011)Y(0.002)R;MGPSGGEGMEPERRDS(0.707)QDGS(0.127)S(0.127)Y(0.038)R;MGPS(0.002)GGEGMEPERRDS(0.909)QDGS(0.039)S(0.039)Y(0.012)R 55.336999999999996 0.024766999999999997 190101900.0 161838.0 91844.1 200335.3 124551.1 119149.3 99464.4 74691.0 93619.6 141018.0 104165.2 True False 159530.16044254586 91631.44062933492 183864.50495062143 133711.00338428965 112141.17243053662 95210.53947484092 78558.13451413026 97969.50839115295 125135.06785462753 122170.01602859562 1.3058045306731036 0.7500321568909942 1.5049887928932197 1.0944666108007441 0.9179107613793583 0.7793282064607042 0.6430230351753626 0.8019112346536961 1.0242698816159432 1.0 16.898530724939192 -6.310259533004243 3.2251646722498677 0.8277185414973435 1.1631297732129087 0.3483472170911047 0.20413304122030795 0.28136097279259675 5.90177126550125 0.06507755951927291 0.07799396903355284 4.894862165381715e-07 6.310259533004243 0.3354112317155652 MGQAPSQSLLPPAQDQPRS(ph)PVPSAFSDQSR ddPTM_PC-9_AZD4547_30min_R2 6 MGQAPSQSLLPPAQDQPRSPVPSAFSDQSR 30 1 Q9UQ35;I3L3Q8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MGQAPSQSLLPPAQDQPRS(0.929)PVPS(0.04)AFS(0.018)DQS(0.013)R;MGQAPS(0.001)QS(0.001)LLPPAQDQPRS(0.912)PVPS(0.055)AFS(0.025)DQS(0.005)R;MGQAPSQS(0.001)LLPPAQDQPRS(0.953)PVPS(0.038)AFS(0.007)DQSR;MGQAPS(0.001)QS(0.001)LLPPAQDQPRS(0.799)PVPS(0.149)AFS(0.024)DQS(0.027)R;MGQAPSQSLLPPAQDQPRS(0.822)PVPS(0.112)AFS(0.061)DQS(0.004)R;MGQAPSQSLLPPAQDQPRS(0.694)PVPS(0.257)AFS(0.048)DQS(0.001)R 71.289 2.5153e-05 668175000.0 101244.8 101533.0 159247.3 252677.0 190933.0 164257.4 131531.4 195378.7 130768.5 184216.1 True False 133438.54037733682 134351.55666396866 157135.5767516628 194426.22147073454 164425.24869348132 153986.35881170133 143237.43978991508 165187.41127088087 137680.65594081618 177766.75041001668 0.7506383509264953 0.7557743861216372 0.8839424492444827 1.093715337779945 0.9249493975348969 0.866226999461563 0.8057605792958458 0.9292368279775507 0.7745017311913367 1.0 17.43962598136953 -5.291184999498137 4.898370130712978 0.9100441834303699 0.7514222008305044 0.3494792294080178 0.08593008568936142 0.20854907177408452 13.513595975584776 0.02370095496452977 0.05486199647938813 5.114639172201278e-06 5.291184999498137 -0.15862198259986549 MGQAPSQSLLPPAQDQPRS(ph)PVPSAFSDQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MGQAPSQSLLPPAQDQPRSPVPSAFSDQSR 30 1 Q9UQ35;I3L3Q8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MGQAPS(0.004)QS(0.003)LLPPAQDQPRS(0.946)PVPS(0.037)AFS(0.009)DQS(0.001)R;MGQAPS(0.002)QS(0.014)LLPPAQDQPRS(0.668)PVPS(0.291)AFS(0.024)DQS(0.001)R 61.693999999999996 0.0010702 129100000.0 22483.0 22131.9 34562.0 39865.0 42626.0 44744.0 44224.0 41783.0 35148.0 30730.0 True False 26288.927840508684 24329.00876736846 35386.08915711492 37631.493294073814 34273.741293301326 42397.545872689705 40034.78256596669 40686.24052274792 35661.97300651683 36301.105741453866 0.7241908284487372 0.6702002120994918 0.9747936993750014 1.0366486784753974 0.9441514409342798 1.1679408934443019 1.102852977843294 1.1207989313748774 0.9823935739178551 1.0 15.147725873319123 -5.367669088061634 3.113522767006874 1.056983006427227 0.6915242755130065 0.8158760288988274 0.06591939222278503 0.10021698367567174 1.8281561813108993 0.018656193753453804 0.046334160300650504 4.288751786170782e-06 5.367669088061634 -0.36545873091422043 MGQAPSQSLLPPAQDQPRS(ph)PVPSAFSDQSR ddPTM_PC-9_Lapatinib_30min_R1 6 MGQAPSQSLLPPAQDQPRSPVPSAFSDQSR 30 1 Q9UQ35;I3L3Q8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MGQAPSQSLLPPAQDQPRS(0.985)PVPS(0.008)AFS(0.006)DQSR;MGQAPS(0.001)QSLLPPAQDQPRS(0.546)PVPS(0.079)AFS(0.354)DQS(0.02)R;MGQAPSQSLLPPAQDQPRS(0.919)PVPS(0.046)AFS(0.015)DQS(0.02)R;MGQAPSQSLLPPAQDQPRS(0.993)PVPS(0.007)AFS(0.001)DQSR;MGQAPSQSLLPPAQDQPRS(0.978)PVPS(0.015)AFS(0.004)DQS(0.003)R;MGQAPS(0.001)QS(0.002)LLPPAQDQPRS(0.864)PVPS(0.121)AFS(0.011)DQS(0.001)R 100.12 7.4849e-13 545125000.0 178952.8 149640.4 170818.4 168355.2 162648.7 167062.5 115194.7 137508.5 177266.7 130994.1 True False 176400.9002560761 149293.91684767854 156774.37053009274 180736.6030244833 153082.0232456475 159917.62631670837 121158.91791400408 143897.64690945964 157301.05754489434 153636.25564633356 1.1481723471714003 0.9717362364736943 1.0204256141921542 1.1763929175710581 0.9963925676374078 1.0408846899057105 0.7886088957603118 0.9366125613000362 1.0238537569348023 1.0 17.229159183132744 -7.033475679424633 24.86914271948939 0.929523671142301 1.0572595858633702 0.3414717875065839 0.08282871715871895 680.9240431745129 505857.58300151234 0.03154541310979053 0.024452466111658532 9.258152295018954e-08 7.033475679424633 0.12773591472106927 MGS(ph)KSPGNTSQPPAFFSK ddPTM_PC-9_AZD4547_30min_R2 2 MGSKSPGNTSQPPAFFSK 18 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2;H7C184 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 MGS(0.832)KS(0.168)PGNTSQPPAFFSK;MGS(0.491)KS(0.491)PGNT(0.008)S(0.01)QPPAFFSK 114.78 6.4975e-05 43952000.0 102412.0 71673.0 144414.0 311704.0 226061.0 141415.0 96457.0 137395.0 90376.0 181752.0 True False 134976.88569806845 94839.89560809397 142498.97600156858 239845.4585787938 194676.33224689844 132572.297694696 105041.48613803105 116163.75977300826 95153.09085373914 175388.91780100344 0.7695861710670537 0.5407405256682151 0.8124742303458885 1.3675063486674959 1.1099694022160427 0.755876137197635 0.5989060623386211 0.662320979167041 0.5425262442276997 1.0 17.4201980663549 -6.98740432353861 23.610796423576243 0.6734544686715387 0.9193699262006969 0.16528397621490276 0.23320208038792592 216.09687718763084 405073.27770413354 0.09100223239614554 0.08019155726895322 1.0294272883347602e-07 6.98740432353861 0.24591545752915822 MGS(ph)KSPGNTSQPPAFFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MGSKSPGNTSQPPAFFSK 18 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2;H7C184 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 MGS(0.593)KS(0.399)PGNT(0.006)S(0.002)QPPAFFSK 69.27199999999999 0.017001 29770000.0 79302.0 25553.0 45780.0 111120.0 107070.0 135360.0 83107.0 161310.0 122760.0 78460.0 True False 92726.26231410493 28089.732966106196 46871.568821616806 104894.30665590061 86090.40210842632 128261.48331233874 75234.50331742475 157075.7834220729 124555.13276089683 92684.17691098175 1.0004540732250726 0.3030693469186752 0.5057127374247976 1.1317390967030547 0.928857599837258 1.3838552338391816 0.8117297453014392 1.694742173444944 1.3438662014609617 1.0 16.500035441803256 -5.806359447880155 5.468999229712053 1.2009034662473732 0.5719886755494786 0.4613873572436018 0.2875425154219436 0.15599199643545797 10.733184462016013 0.0812574588579028 0.12539528669930178 1.5618544241554872e-06 5.806359447880155 -0.6289147906978946 MGS(ph)KSPGNTSQPPAFFSK ddPTM_PC-9_Lapatinib_30min_R1 1 MGSKSPGNTSQPPAFFSK 18 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2;H7C184 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 MGS(0.482)KS(0.482)PGNT(0.016)S(0.02)QPPAFFSK 63.979 0.025252 11462000.0 116890.0 33521.0 80377.0 67846.0 54024.0 59654.0 39653.0 40070.0 68135.0 37375.0 True False 115223.12716499911 33443.384184024086 73768.71332419229 72835.62116762123 50846.4145352706 57102.73748026597 41706.03831638091 41931.79848272682 60460.9188066421 43835.218950942915 2.6285514233189566 0.7629341197417403 1.682864032383383 1.66157767454369 1.1599443495919135 1.3026680109473403 0.9514276263352346 0.9565778268303791 1.3792772171231862 1.0 15.419802833598185 -4.749458349060812 24.999847872988664 1.227714768635826 2.6285545831525683 0.6821457939697206 0.29091329824074313 340.1197258443086 709656.6957149218 0.07451621036765607 1.2175560243135892 1.7804986590899242e-05 4.749458349060812 1.4008398145167422 MGS(ph)PAPLLPGDLLGGGSDSI ddPTM_PC-9_AZD4547_30min_R2 6 MGSPAPLLPGDLLGGGSDSI 20 0 Q9UPQ9-1;Q9UPQ9;Q9UPQ9-2 Q9UPQ9-1 TNRC6B Trinucleotide repeat-containing gene 6B protein 1 MGS(1)PAPLLPGDLLGGGSDSI;MGS(1)PAPLLPGDLLGGGSDSI;MGS(1)PAPLLPGDLLGGGSDSI;MGS(1)PAPLLPGDLLGGGSDSI;MGS(1)PAPLLPGDLLGGGSDSI;MGS(1)PAPLLPGDLLGGGSDSI 132.59 1.3778e-06 8399360.0 32279.700000000004 26468.399999999998 42400.299999999996 47384.2 45103.420000000006 41725.35 36626.4 47022.06 36917.200000000004 45451.04 True False 42543.973140529924 35023.79268222729 41838.04431813615 36460.504768592255 38841.58867470027 39116.25726843244 39886.07864526149 39755.88108644409 38868.56782404245 43859.8129238199 0.9699989649847467 0.7985394908788167 0.9539038479440082 0.831296404111903 0.8855849144218699 0.8918473349709324 0.9093991968123442 0.9064307035576296 0.886200036729597 1.0 15.420612038016658 -12.044750072248476 0.34871452679351406 1.1740591222616577 0.8853666274834701 0.3079385299340579 0.048008813620518266 67.41184775382347 2.6940963616216327 8.914442592562585 0.03442858446339261 9.020901230060927e-13 12.044750072248476 -0.2886924947781876 MGS(ph)PAPLLPGDLLGGGSDSI ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 MGSPAPLLPGDLLGGGSDSI 20 0 Q9UPQ9-1;Q9UPQ9;Q9UPQ9-2 Q9UPQ9-1 TNRC6B Trinucleotide repeat-containing gene 6B protein 1 MGS(1)PAPLLPGDLLGGGSDSI;MGS(1)PAPLLPGDLLGGGSDSI;MGS(1)PAPLLPGDLLGGGSDSI;MGS(1)PAPLLPGDLLGGGSDSI;MGS(1)PAPLLPGDLLGGGSDSI;MGS(1)PAPLLPGDLLGGGSDSI 118.31 1.3144000000000002e-05 3760140.0 17935.93 15056.31 16197.39 19219.719999999998 19590.04 17229.079999999998 18540.65 16714.9 12970.99 11435.15 True False 20972.128698234883 16551.0009531137 16583.597206543636 18142.901399572962 15751.51229027881 16325.556714738086 16784.345409318248 16276.15158590047 13160.666190047788 13508.2521744024 1.5525419889611056 1.225251108687265 1.2276641709405525 1.3430976239807721 1.1660659045237027 1.2085617372227004 1.2425253239737346 1.2049043337185494 0.974268618925158 1.0 13.721553396740962 -1.5228787453218733 0.1240137616686045 0.9155134810444889 2.523805314425955 0.6402584281622166 0.09254554040348068 63.132134506994475 0.5368884195201201 0.5823904980038763 17.614284470491164 0.029999999997130815 1.5228787453218733 1.608291833381466 MGS(ph)PAPLLPGDLLGGGSDSI ddPTM_PC-9_Lapatinib_30min_R1 6 MGSPAPLLPGDLLGGGSDSI 20 0 Q9UPQ9-1;Q9UPQ9;Q9UPQ9-2 Q9UPQ9-1 TNRC6B Trinucleotide repeat-containing gene 6B protein 1 MGS(1)PAPLLPGDLLGGGSDSI;MGS(1)PAPLLPGDLLGGGSDSI;MGS(1)PAPLLPGDLLGGGSDSI;MGS(1)PAPLLPGDLLGGGSDSI;MGS(1)PAPLLPGDLLGGGSDSI;MGS(1)PAPLLPGDLLGGGSDSI 150.01 7.3439e-06 16044500.0 91693.2 85853.8 86849.70000000001 84971.5 80478.3 70874.0 64555.0 74859.9 74726.3 60533.600000000006 True False 90385.63815352654 85655.01080094169 79709.25291553697 91220.58756661451 75744.72462042554 67842.8842353635 67897.3420299591 78338.164243501 66309.8371911761 70996.75210404821 1.2730953948578274 1.2064637925325272 1.1227168927209557 1.2848557837255368 1.0668759115828146 0.9555772936758767 0.9563443399559064 1.1034049012368017 0.9339840940047051 1.0 16.11546540655324 -6.4522618541194365 4.601318693718548 0.9952054230110728 1.2124985832232784 0.7688403521086877 0.05989935382379291 0.10901768554560795 4.3899564027693385 0.01897586523583525 0.021211474710369875 3.529702852248559e-07 6.4522618541194365 0.21729316021220557 MGS(ph)PEER ddPTM_PC-9_Lapatinib_30min_R1 1 MGSPEER 7 0 Q15042-4;Q15042;Q15042-3 Q15042-4 RAB3GAP1 Rab3 GTPase-activating protein catalytic subunit 1 MGS(1)PEER 72.87899999999999 0.033208999999999995 1372400.0 21092.0 18500.0 20702.0 12645.0 17845.0 16656.0 15226.0 14264.0 18778.0 13804.0 True False 20791.224212200916 18457.164386636603 18999.961472030966 13574.955482483427 16795.39218461987 15943.661707032377 16014.327778609835 14926.757513292117 16663.02389889374 16190.003007326182 1.2842013804934207 1.140034648436106 1.173561330620707 0.8384776381042417 1.0373927773218905 0.9847843573480294 0.9891491540404994 0.9219737332066936 1.0292168501360692 1.0 13.982815633173509 -5.650213732287129 7.572460001574571 0.9726715398891345 1.1979275409249637 0.7317893637564123 0.06329691430598554 0.112813929897361 7.076058123615112 0.016443726215324517 0.0285690769188993 2.237619652622944e-06 5.650213732287129 0.2252560010358292 MGS(ph)SPLEVPKPR ddPTM_PC-9_AZD4547_30min_R2 1 MGSSPLEVPKPR 12 1 Q8NCE2-2;Q8NCE2 Q8NCE2-2 MTMR14 Myotubularin-related protein 14 1 MGS(0.5)S(0.5)PLEVPKPR 88.22399999999999 0.012412999999999999 8181300.0 54613.0 47383.0 76371.0 91418.0 78832.0 76999.0 63815.0 78284.0 73573.0 80910.0 True False 71978.7979790319 62698.62812493295 75358.27064007505 70342.99249402054 67887.53753936988 72184.24035776881 69494.4113739642 66187.00658735908 77461.91857774359 78077.3655270873 0.9218907104909984 0.8030320657166766 0.9651743515081984 0.9009396259613359 0.8694906274190018 0.924521977278114 0.8900711608904707 0.8477105514580521 0.9921174729041006 1.0 16.252616754105887 -8.279502988339212 23.05152822016959 0.9960588809937059 0.8907241052385699 0.5013076801553646 0.04217020789454132 272.01337560533955 347115.9122693803 0.03856648818691847 0.010070826461053511 5.2540839981218655e-09 8.279502988339212 -0.10533477575513595 MGSDEFDIS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 MGSDEFDISPR 11 0 Q8IWI9-3;Q8IWI9 Q8IWI9-3 MGA MAX gene-associated protein 1 MGS(0.042)DEFDIS(0.958)PR 74.237 0.020307 2808500.0 24006.0 28860.0 32642.0 23047.0 25884.0 31172.0 28508.0 27406.0 27765.0 21950.0 True False 23663.67003783876 28793.176443153097 29958.300761763832 24741.95326253822 24361.554009901985 29838.846225481102 29984.004749284704 28679.382810521878 24637.8133215883 25744.02825346348 0.9191906489869224 1.1184409898742012 1.1636990321331466 0.9610754392801583 0.946299225981641 1.159058944921206 1.1646974767925373 1.1140207945764466 0.9570302315945308 1.0 14.651950194048077 -6.772049046938803 24.996688350226886 1.0914462622853356 1.0316295157907192 0.07384269731861048 0.09314352325596031 599.8114238973078 1413163.5889496536 0.034275794983577884 0.030533976965359155 1.6902500328987683e-07 6.772049046938803 -0.059816746494616435 MGSDGESDQASGTSSDEVQS(ph)PTGVCLR ddPTM_PC-9_AZD4547_30min_R2 1 MGSDGESDQASGTSSDEVQSPTGVCLR 27 0 Q00537-2;Q00537;F5H6Z0;F8VQZ9;F8VZY6 Q00537-2 CDK17 Cyclin-dependent kinase 17 1 MGSDGESDQASGTSSDEVQS(0.886)PT(0.114)GVCLR 115.92 5.6485e-07 0.0 1082.3 2488.8 4986.2 7370.0 5271.9 5153.4 3711.7 5505.0 4474.6 4521.8 True False 1426.4488867615107 3293.255928863374 4920.079730074795 5670.960365364929 4539.987684617981 4831.157083335185 4042.034109484332 4654.328742315304 4711.118220923049 4363.493158328803 0.3269052648882424 0.7547292523141426 1.1275552754525604 1.299637735088573 1.040447989691996 1.1071765001198022 0.9263298836092164 1.0666520087080622 1.0796666913366688 1.0 12.091267819771996 -4.914849510120656 2.4972183753501187 1.0841168258206155 0.2665498256902152 0.8642174468881394 0.09331292751959017 0.13848591222033368 1.36698258358199 0.026599560224049263 0.21641423240294497 1.2166075012780421e-05 4.914849510120656 -0.8175670001304003 down MGSDGESDQASGTSSDEVQS(ph)PTGVCLR ddPTM_PC-9_Lapatinib_30min_R1 1 MGSDGESDQASGTSSDEVQSPTGVCLR 27 0 Q00537-2;Q00537;F5H6Z0;F8VQZ9;F8VZY6 Q00537-2 CDK17 Cyclin-dependent kinase 17 1 MGSDGESDQASGTSSDEVQS(0.974)PT(0.026)GVCLR 136.08 7.9139e-16 0.0 1666.2 1890.9 4563.6 3994.2 3387.2 2864.7 3057.5 4437.2 3510.7 1735.8 True False 1642.4396824563432 1886.5217372265504 4188.3984240054315 4287.946792260604 3187.971555491421 2742.1834589418613 3215.8023895376027 4643.368510794994 3115.287996690076 2035.8307171918848 0.8067663330681227 0.9266594325822517 2.05734120653346 2.10623936265937 1.565931552446923 1.3469604499947232 1.579602057470332 2.280822502373776 1.530229390087569 1.0 10.991401888501386 -5.196100976567663 7.316960836388156 1.723778702859966 0.8549913629718036 0.44359313733243544 0.36375906819230913 0.24154363052220318 23.56740906002514 0.09285298560745071 0.24875388204275356 6.3664747861405225e-06 5.196100976567663 -0.8687873398881625 MGSFSSHMTEFPRK ddPTM_PC-9_Lapatinib_30min_R1 1 MGSFSSHMTEFPRK 14 1 Q8WYA1-6;Q8WYA1-8;Q8WYA1-7 Q8WYA1-6 ARNTL2 Aryl hydrocarbon receptor nuclear translocator-like protein 2 0 64.297 0.027868 0.0 9489.4 10641.0 7490.8 9175.5 11883.0 11309.0 11277.0 11204.0 8929.2 7348.1 False True 9354.079415857168 10616.361418281087 6874.935339324196 9850.296878570713 11184.065302876872 10825.340432566592 11860.86788121522 11724.578742212905 7923.499467355529 8618.209294272201 1.085385501379508 1.2318523553769911 0.7977220214289049 1.1429632934439613 1.2977249589784248 1.2561008978699655 1.3762566533511944 1.3604425631674142 0.9193904669525272 1.0 13.073172419562244 -5.997644460826802 24.99974372579273 1.2301470594515331 1.0431181142469013 0.14279598938062077 0.17050777778963008 123.91523856328507 1315088.4386326957 0.047600828548948676 0.07010401977336786 1.0054385649778407e-06 5.997644460826802 -0.18702894520463187 MGSKS(ph)PGNTSQPPAFFSK ddPTM_PC-9_AZD4547_30min_R2 2 MGSKSPGNTSQPPAFFSK 18 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2;H7C184 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 MGS(0.293)KS(0.706)PGNT(0.001)SQPPAFFSK;MGS(0.342)KS(0.612)PGNT(0.037)S(0.009)QPPAFFSK 89.20100000000001 0.00069087 46515000.0 122092.0 67167.0 138811.0 356840.0 258000.0 144552.0 103685.0 152857.0 102389.0 174400.0 True False 160914.71632863942 88877.41922772664 136970.27544250368 274576.051123042 222181.15340416963 135513.14058878942 112912.76413553981 129236.46295442166 107801.07350871358 168294.30908322896 0.9561506696525311 0.5281070982844277 0.8138734826426355 1.6315230896325321 1.3201940969631436 0.8052152287679092 0.6709244344067479 0.7679193887091483 0.6405509140264583 1.0 17.36062686681342 -6.974263637199324 24.214459026387008 0.7487315690431262 1.0424230881796566 0.18258552123279126 0.28803738230085363 299.0452476206355 281359.8510284823 0.11435654296515446 0.1008490447066441 1.0610512535865405e-07 6.974263637199324 0.29369151913653035 MGSKS(ph)PGNTSQPPAFFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MGSKSPGNTSQPPAFFSK 18 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2;H7C184 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 MGS(0.264)KS(0.725)PGNT(0.008)S(0.003)QPPAFFSK 68.705 0.017854 24733000.0 75264.0 24803.0 59218.0 132490.0 122310.0 141040.0 104790.0 170560.0 118910.0 88034.0 True False 88004.70866824039 27265.27792268353 60629.98170551565 125067.01483837566 98344.23350968164 133643.61411327004 94863.53258609895 166082.98072325776 120648.83379438156 103993.86732323939 0.8462490234611563 0.2621815942082057 0.5830149725758563 1.2026383676033083 0.945673394412795 1.2851105315457854 0.9122031426260836 1.5970459124000995 1.1601533523065768 1.0 16.66613892738758 -5.7386005374672004 6.29366829934028 1.1695066178182356 0.5274112639285309 0.5878380272053405 0.22723319076440252 0.10572958314015646 14.055854782435588 0.06072082811428681 0.10227429004929713 1.8255740869219672e-06 5.7386005374672004 -0.6420953538897047 MGSKS(ph)PGNTSQPPAFFSK ddPTM_PC-9_Lapatinib_30min_R1 2 MGSKSPGNTSQPPAFFSK 18 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2;H7C184 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 MGS(0.199)KS(0.591)PGNT(0.155)S(0.055)QPPAFFSK;MGS(0.37)KS(0.609)PGNT(0.012)S(0.009)QPPAFFSK 62.707 0.0094485 32667000.0 283770.0 93502.0 207541.0 157191.0 125239.0 134999.0 86671.0 87345.0 170544.0 103859.0 True False 279723.38776295504 93285.50186374589 190477.78011142727 168751.350513804 117872.68824934747 129225.4074680394 91158.40029554002 91403.36756859938 151335.53881206387 121810.88976658146 2.296374226466709 0.7658223500583816 1.5637171723844054 1.3853552078732172 0.9676695447773142 1.0608690874491264 0.7483600232312655 0.7503710689885765 1.2423810309739847 1.0 16.894283588879468 -4.752997795244835 24.99491899640844 1.0603118236958105 2.296376538722476 0.6698888370450037 0.2616374393363453 205.74442924911892 609147.8552692977 0.06927083745277263 0.7795146734428832 1.7660467862407647e-05 4.752997795244835 1.2360647150266655 MGSS(ph)PLEVPKPR ddPTM_PC-9_AZD4547_30min_R2 1 MGSSPLEVPKPR 12 1 Q8NCE2-2;Q8NCE2 Q8NCE2-2 MTMR14 Myotubularin-related protein 14 1 MGS(0.056)S(0.944)PLEVPKPR 106.79 0.0042247 0.0 15202.0 16268.0 17408.0 29248.0 26196.0 17991.0 17107.0 21044.0 18983.0 22074.0 True False 20035.919778756786 21526.312861921142 17177.158545814855 22505.32547709546 22559.13757587448 16866.019925929148 18629.48985934976 17792.13334301241 19986.402625437404 21301.195978802694 0.9406006967259015 1.0105682743514715 0.8063940899331773 1.0565287272832484 1.059054975050396 0.7917874631411733 0.8745748303470091 0.8352645250866556 0.9382760782693295 1.0 14.378646813955896 -6.762231847869455 24.999999250932877 0.8768467643001084 0.9718295127536104 0.19979535122665004 0.08516847574359773 33.31986396419965 1051117.1869414807 0.02910056193948107 0.02718940625862216 1.7288931441573564e-07 6.762231847869455 0.09498274845350196 MGSS(ph)PLEVPKPR ddPTM_PC-9_Lapatinib_30min_R1 2 MGSSPLEVPKPR 12 1 Q8NCE2-2;Q8NCE2 Q8NCE2-2 MTMR14 Myotubularin-related protein 14 1 MGS(0.23)S(0.77)PLEVPKPR;MGS(0.062)S(0.938)PLEVPKPR 110.44 0.00056276 13931900.0 39524.0 37231.0 52238.0 48072.0 42872.0 45682.0 36178.0 54484.0 57391.0 51439.0 True False 38960.38051218608 37144.79390696583 47943.193284511304 51607.37524349096 40350.35324959503 43728.28734994316 38051.1198196865 57015.52554362088 50927.02122597779 60330.16261184086 0.6457861014374162 0.6156919242196027 0.794680325875694 0.8554158153945055 0.6688255344048345 0.7248163349283052 0.630714690170888 0.9450583766938261 0.8441386368148536 1.0 15.880591850509598 -7.770805778275015 24.998360239639457 0.9209489563487275 0.7102777719089828 0.6288209022918306 0.078920618185914 147.4916492176992 393639.6840428505 0.044649705490203605 0.02190499675964954 1.6950956981840997e-08 7.770805778275015 -0.21067118443974475 MHACTAS(ph)S ddPTM_PC-9_AZD4547_30min_R2 1 MHACTASS 8 0 Q8TDX7 Q8TDX7 NEK7 Serine/threonine-protein kinase Nek7 1 MHACTAS(0.593)S(0.406) 74.127 0.024855000000000002 309480.0 1139.0 706.86 1156.4 1038.8 1672.9 1214.5 1027.2 2109.3 2082.6 881.08 True False 1501.1783073282447 935.3386715993099 1141.0653804216622 799.3207093000118 1440.6467113559477 1138.5571230082232 1118.6188100499255 1783.3561518920394 2192.6819842878335 850.2336573798804 1.7656067767939765 1.1000960306390282 1.3420609387988973 0.9401188748081741 1.6944127050856956 1.3391108586748424 1.3156604662030358 2.097489479995079 2.5789169427200807 1.0 9.731715560459568 -7.757904760329752 24.960187148916063 2.003652493425066 1.3425768327314282 0.2313689271217847 0.4325854813703281 98.62945558289707 696501.3079892272 0.20093057462334096 0.11007921555310156 1.7462050492405776e-08 7.757904760329752 -0.6610756606936377 MHEFHS(ph)QENLVVHIPK ddPTM_PC-9_Lapatinib_30min_R1 1 MHEFHSQENLVVHIPK 16 0 H3BRG5;Q9Y3M8-5;Q9Y3M8-3;Q9Y3M8-4;Q9Y3M8-2;Q9Y3M8 H3BRG5 STARD13 StAR-related lipid transfer protein 13 1 MHEFHS(1)QENLVVHIPK 70.942 0.018877 2925900.0 6703.6 5967.8 6233.8 6872.5 6705.3 5323.4 4301.4 6928.8 5110.0 4275.2 True False 6608.005434710323 5953.98192576054 5721.281027163876 7377.926575987931 6310.907437127015 5095.730591451499 4524.105445088158 7250.737342827987 4534.457989314464 5014.16262365408 1.3178681926943023 1.1874329519495253 1.141024226093904 1.4714174887712865 1.2586164252742027 1.0162675154197485 0.9022653999584898 1.4460514919526084 0.904330060601419 1.0 12.291793072324683 -6.725947359081405 9.445866660781695 1.0722437098093225 1.2741485902470495 0.30820368814388344 0.1647638079850209 0.4797816398658111 121.16767239374954 0.054317942740136134 0.05395971561099325 1.8795446229659793e-07 6.725947359081405 0.20190488043772703 MHLPS(ph)PTDSNFYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MHLPSPTDSNFYR 13 0 P00533;E9PFD7;Q504U8 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 MHLPS(0.964)PT(0.035)DSNFYR;MHLPS(0.998)PT(0.002)DSNFYR 70.134 0.020044 8202000.0 31755.0 26860.0 34383.0 29318.0 52694.0 33571.0 35870.0 35037.0 32703.0 26204.0 True False 37130.49431016115 29526.48328844413 35202.82111825362 27675.407510238456 42368.98896704402 31810.477661632078 32472.133923689053 34117.31587477009 33181.21950700241 30954.577769250125 1.1995154508954762 0.9538648373286924 1.137241198399535 0.8940650948801132 1.368747113363401 1.0276501879225177 1.0490252577745205 1.1021735178911658 1.071932550795902 1.0 14.917865160123904 -9.283202504163004 0.9883966667995576 0.9994591519336379 1.0885255176124302 0.045712104821623134 0.12436378521346504 14.994565880160636 16.351523962360986 0.13137199680050182 0.036431775804106635 5.209517434869264e-10 9.283202504163004 0.08906636567879234 MHLPS(ph)PTDSNFYR ddPTM_PC-9_Lapatinib_30min_R1 2 MHLPSPTDSNFYR 13 0 P00533;E9PFD7;Q504U8 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 MHLPS(0.984)PT(0.016)DS(0.001)NFYR;MHLPS(0.992)PT(0.007)DSNFYR 76.574 0.011848000000000001 7397700.0 54829.0 49242.0 29916.0 19658.8 43097.0 31606.0 27140.0 25580.0 46457.0 21429.8 True False 54047.128405592855 49127.98317441948 27456.421959099516 21104.573731834353 40562.11919196205 30254.285057184527 28545.17640296011 26768.54018438113 41224.5234461022 25133.912376586395 2.150366707569996 1.954649257876178 1.0924054141557629 0.8396851797531693 1.6138402403975858 1.2037236624318002 1.1357235584839347 1.0650367433172672 1.6401952401371893 1.0 14.617347639982976 -5.193295327890829 4.776215513597723 1.2010184456218602 2.091055718723041 0.6694489023443606 0.24078600874628303 0.12207956718535073 5.408602011034721 0.061446896407914516 0.1728002414265157 6.4077369101018455e-06 5.193295327890829 0.8900372731011807 MHLY(ph)PADFRFDKPKK ddPTM_PC-9_AZD4547_30min_R2 1 MHLYPADFRFDKPKK 15 3 H7BY64;Q8NB15;Q8NB15-1 H7BY64 PRAP1;ZNF511 Zinc finger protein 511 1 MHLY(1)PADFRFDKPKK 62.162 0.021808 8826100.0 26231.0 28002.0 18247.0 16558.0 21208.0 25067.0 31553.0 19429.0 23624.0 23651.0 True False 34571.91236130573 37053.098891044756 18005.032857621998 12740.808918549857 18263.635276727207 23499.556527334003 34361.15587373958 16426.694484004372 24872.716410648136 22822.98568880413 1.5147848240673027 1.6234991949024988 0.7888990994922461 0.5582446176093382 0.8002298877874895 1.0296442738805103 1.5055504280754788 0.7197434510973088 1.089809928893287 1.0 14.478199915990718 -5.256535592761903 24.760232694368952 0.9317777708697589 1.569142089896941 0.5176402467124464 0.24424077547557055 294.2891083588039 1485911.8157214115 0.06755911138255638 0.16712106419657355 5.5394214354877425e-06 5.256535592761903 0.6373643190271822 MHVEHER ddPTM_PC-9_Lapatinib_30min_R1 1 MHVEHER 7 0 Q15424-2;Q15424;Q15424-4;Q15424-3;K7EII0 Q15424-2 SAFB Scaffold attachment factor B1 0 75.189 0.022446999999999998 499170.0 707.9 855.9 701.82 1087.4 977.65 584.36 2466.6 1335.6 1099.3 1055.2 False True 697.805216187039 853.9182161363397 644.1190687035441 1167.3710234600624 920.1465491338528 559.3682850096927 2594.3084788335073 1397.656851847515 975.485257857807 1237.5899140343804 0.5638420354544469 0.6899847893497116 0.5204624418793142 0.9432615846509175 0.7434987459895306 0.45198193574980394 2.0962585824381863 1.1293376230671899 0.7882136455668529 1.0 10.273317629102175 MIAGQVLDINLAAEPK ddPTM_PC-9_Lapatinib_30min_R1 1 MIAGQVLDINLAAEPK 16 0 B4DY08;B2R5W2;G3V4W0;G3V576;G3V555;G3V575;G3V5X6;G3V3K6;G3V251;B4DSU6;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 0 145.49 0.00039547 3287000.0 24097.0 23085.0 23859.0 20131.0 20684.0 23122.0 20519.0 20099.0 20922.0 21310.0 False True 23753.37236115142 23031.54810083818 21897.405118403374 21611.500895047357 19467.407786308624 22133.125960014575 21581.37341976193 21032.872915006898 18565.54404157284 24993.40510620985 0.9503856021302863 0.9215050131410774 0.8761273234019142 0.8646881368588617 0.7789017824334692 0.8855586450089342 0.8634827198635624 0.8415369104620753 0.742817713820037 1.0 14.609259847408058 -5.269679462896822 1.6328548651925783 0.8456724000340604 0.9525105372142431 0.20376812876380102 0.06408980147495286 0.6894638379957087 3.0902029352349816 0.017992657444716655 0.08573398719007293 5.374283064890403e-06 5.269679462896822 0.10683813718018265 MIIY(ph)RDLISHDEMFS(ph)DIY(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 MIIYRDLISHDEMFSDIYK 19 1 Q5W0H4;A0A0B4J2C3;P13693 Q5W0H4 TPT1 Translationally-controlled tumor protein 3 MIIY(0.931)RDLIS(0.075)HDEMFS(0.994)DIY(1)K 52.853 0.012206 17331000.0 18115.0 20944.0 22422.0 19745.0 20219.0 27345.0 28721.0 38368.0 34356.0 24125.0 True False 23875.193184592772 27713.738417757348 22124.66962972546 15193.09530720903 17411.940855344557 25635.112827220997 31277.11336005053 32439.1072089289 36171.98802083589 23280.391093078488 1.0255494888009473 1.1904326824645546 0.9503564412327834 0.652613405267324 0.7479230389957373 1.101146141605954 1.343496045019173 1.3934090316280554 1.5537534518305498 1.0 14.506827674191932 -7.0971223717452325 3.399941724891395 1.3552241551980364 0.9162852572384405 0.5051513697992985 0.18893085844654708 0.21293446894190765 4.62343858705521 0.08171271342304783 0.06272020777950561 7.996089163725963e-08 7.0971223717452325 -0.43893889795959595 MIIY(ph)RDLISHDEMFS(ph)DIY(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MIIYRDLISHDEMFSDIYK 19 1 Q5W0H4;A0A0B4J2C3;P13693 Q5W0H4 TPT1 Translationally-controlled tumor protein 3 MIIY(0.872)RDLIS(0.129)HDEMFS(0.999)DIY(1)K;MIIY(0.904)RDLIS(0.198)HDEMFS(0.899)DIY(0.998)K 56.407 0.008333700000000001 24989000.0 13087.0 15592.800000000001 16557.1 16124.6 23983.0 20654.7 25462.0 20120.3 23453.0 18277.9 True False 15302.370619967853 17140.750134774815 16951.88405715142 15221.190938658541 19283.703313406022 19571.531171478735 23050.05503108367 19592.163444220034 23795.955756283132 21591.538582223213 0.7087207130559297 0.7938642292442823 0.7851170027831308 0.7049609216450411 0.8931139038550369 0.9064444896758032 1.067550371332096 0.9074000618163771 1.1020963450874623 1.0 14.39817843096244 -6.679651235361204 1.5838057727459818 1.0112779042548432 0.7528726684817102 0.7931524730316332 0.06041233995434705 0.16191855519416207 0.8414977515901825 0.024003085065880062 0.02329472170282087 2.0909746354244045e-07 6.679651235361204 -0.258405235773133 MIIY(ph)RDLISHDEMFS(ph)DIY(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 MIIYRDLISHDEMFSDIYK 19 1 Q5W0H4;A0A0B4J2C3;P13693 Q5W0H4 TPT1 Translationally-controlled tumor protein 3 MIIY(0.808)RDLIS(0.216)HDEMFS(0.976)DIY(0.999)K 40.515 0.039865 10989000.0 5731.2 9188.7 7276.9 5261.0 9218.7 9171.1 11832.0 8764.5 8941.1 9494.3 True False 5649.472037026639 9167.424129702044 6678.621371646316 5647.911490181523 8676.474190661542 8778.873431878286 12444.603065579371 9171.730666380314 7934.059164042965 11135.377104640464 0.5073444737378786 0.8232701994332718 0.5997660706850353 0.5072043305859718 0.7791809930752844 0.7883768416087006 1.1175735629459116 0.823656943109557 0.71250924773231 1.0 13.442862796030104 -6.645646905456581 2.478714076862266 0.8979578377998101 0.6260469875220582 0.4891808193913362 0.1337133197614115 0.26645204130014427 3.333491085801546 0.04967054424041688 0.04930744783352323 2.2612735067760997e-07 6.645646905456581 -0.27191085027775186 MIPCDFLIPVQTQHPIR ddPTM_PC-9_Lapatinib_30min_R1 1 MIPCDFLIPVQTQHPIR 17 0 P06744-2;P06744;A0A2U3TZU2;K7EQ48;K7ESF4 P06744-2 GPI Glucose-6-phosphate isomerase 0 95.06700000000001 0.0011444 2934400.0 27027.0 22410.0 26533.0 19822.0 21820.0 23985.0 21583.0 21402.0 22655.0 21742.0 False True 26641.590023855228 22358.11102186629 24351.559160341872 21279.776004253585 20536.590499770562 22959.217461765827 22700.462133569927 22396.415051842272 20103.35533227382 25500.075730606048 1.044765133457196 0.8767860636206399 0.9549602682596865 0.8344985414577762 0.8053540984241806 0.9003587951783768 0.8902115575415358 0.8782881779822066 0.7883645344686211 1.0 14.638213911182898 MIPLEKPGSGGS(ph)SPGATSGSGR ddPTM_PC-9_AZD4547_30min_R2 1 MIPLEKPGSGGSSPGATSGSGR 22 1 Q9UEE5 Q9UEE5 STK17A Serine/threonine-protein kinase 17A 1 MIPLEKPGS(0.111)GGS(0.387)S(0.387)PGAT(0.081)S(0.027)GS(0.006)GR 47.485 0.025222 9379900.0 31905.0 24728.0 38961.0 43038.0 38184.0 37023.0 30200.0 36017.0 29666.0 40125.0 True False 42050.12633477406 32720.84241760425 38444.35168333482 33116.25403047162 32882.81070381701 34707.945957293916 32887.74149484789 30451.40023832342 31234.08419566065 38720.23596309946 1.0859987107219078 0.8450579291094027 0.9928749328896765 0.8552699436550836 0.8492409688606872 0.8963774391863398 0.8493683128943232 0.786446659760641 0.8066604817549886 1.0 15.240800124046155 -1.5228913770589065 0.8596126202134217 0.8593037792299295 76.8258450211087 0.4096475441272408 0.07079343051000529 686.2825168783806 1.8244066387422462 0.023525485740778593 102021.77149146248 0.02999912744033866 1.5228913770589065 75.96654124187877 MIS(ph)TVVWLMVLLIMVPNMMIPIK ddPTM_PC-9_Lapatinib_30min_R1 1 MISTVVWLMVLLIMVPNMMIPIK 23 0 O14626 O14626 GPR171 Probable G-protein coupled receptor 171 1 MIS(0.958)T(0.042)VVWLMVLLIMVPNMMIPIK 57.482 0.03035 0.0 8117.6 6715.5 5005.5 7067.7 6208.0 5315.2 5734.2 6264.8 6556.6 6403.7 True False 8001.84153541448 6699.950672349088 4593.96711178876 7587.482235156045 5842.857645397595 5087.881286336365 6031.088818343915 6555.885478776815 5818.126663941137 7510.571012606106 1.065410542285507 0.892069412712238 0.61166682321198 1.0102403961590734 0.7779511884769693 0.6774293562761897 0.8030133538742984 0.8728877561736783 0.7746583654126579 1.0 12.874706881581202 -4.857730029425437 3.997865888574096 0.8084960422864121 1.0700175890398214 0.2845015622051118 0.11857575828252534 0.2609513627950806 6.925909021535744 0.02852308685460674 0.16401154952823413 1.3876181461971047e-05 4.857730029425437 0.2615215467534092 MISTPS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 MISTPSPK 8 0 Q53F19;Q53F19-2 Q53F19 C17orf85 Uncharacterized protein C17orf85 1 MIS(0.01)T(0.052)PS(0.937)PK 79.48899999999999 0.020640000000000002 27365000.0 341120.0 258580.0 296770.0 391480.0 353870.0 352810.0 359760.0 343070.0 331110.0 365580.0 True False 449589.06426322256 342160.92819249915 292834.6358939267 301230.33430570696 304741.2587408263 330748.7349267445 391777.94305253256 290056.4144643249 348611.79862553754 352781.15547389106 1.2744134920111858 0.9698957069656237 0.8300744848475873 0.8538730871297934 0.8638252185876176 0.9375464924776086 1.1105410166431853 0.822199286905481 0.988181463823506 1.0 18.42841397288759 -4.773030107723876 4.094717291186306 0.9204206516493119 1.3072030249169628 0.5962054804025161 0.08540608713109502 0.1557960954101567 5.068943872048966 0.021819191986367174 0.1799954536615922 1.6864361081474897e-05 4.773030107723876 0.38678237326765097 MISTPS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MISTPSPK 8 0 Q53F19;Q53F19-2 Q53F19 C17orf85 Uncharacterized protein C17orf85 1 MIS(0.05)T(0.013)PS(0.937)PK;MIS(0.026)T(0.017)PS(0.957)PK 75.652 0.026068 10869500.0 135188.0 141195.0 105353.0 151960.0 138109.0 114597.0 134053.0 142008.0 114463.0 103037.0 True False 158072.65831529134 155211.90647475334 107865.01507347764 143446.17386096733 111047.53287375173 108587.33158351119 121354.52938032612 138280.44046991345 116136.8048322791 121716.79245955657 1.2986922767276743 1.2751889311109341 0.8861966610672761 1.1785241047050339 0.9123435692790708 0.8921310641634926 0.9970237214445917 1.136083507260188 0.954155975403874 1.0 16.89316869529759 -5.2440026843753325 23.213821891303695 0.999481502940159 1.2869408379283216 0.6163923308441588 0.09219754674647747 211.34250876447226 281361.0477109302 0.023420832863444187 0.06155862840739787 5.701607481047756e-06 5.2440026843753325 0.28745933498816256 MISTPS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 MISTPSPK 8 0 Q53F19;Q53F19-2 Q53F19 C17orf85 Uncharacterized protein C17orf85 1 MIS(0.001)T(0.009)PS(0.99)PK;MIS(0.002)T(0.013)PS(0.984)PK 82.029 0.017048 52974000.0 924910.0 749670.0 732770.0 705250.0 656570.0 508790.0 617450.0 632140.0 607680.0 686990.0 True False 911720.6137922789 747934.1851745889 672524.4791739988 757116.4376450336 617951.8434662849 487030.2377474187 649418.5397939469 661511.5321405267 539236.6792459127 805735.3061433653 1.1315386167651136 0.9282628916369071 0.8346717266158072 0.9396590069621686 0.7669414989695538 0.6044543835103595 0.8059948904341485 0.8210035319251894 0.6692479219099352 1.0 19.619946448137526 -3.3511762226129975 0.6691424050588971 0.7732779519089367 3.2650519738776937 0.4766559010810344 0.10700884611644373 15.16605997225605 1.1422867344172285 0.04385404115253038 44.13738098040703 0.00044547545223130874 3.3511762226129975 2.491774021968757 MISTPS(ph)PKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MISTPSPKK 9 1 Q53F19;Q53F19-2 Q53F19 C17orf85 Uncharacterized protein C17orf85 1 MIS(0.002)T(0.073)PS(0.924)PKK 77.062 0.022706 17731000.0 105410.0 91803.0 69758.0 113070.0 107440.0 103870.0 106220.0 129860.0 87756.0 86212.0 True False 123253.83105759976 100916.59513510956 71421.29527868825 106735.05447788621 86387.90326449345 98422.8743473154 96158.07263379593 126451.31259804346 89039.265481959 101841.55314618349 1.210250897103671 0.9909176757178256 0.7012981741958515 1.0480501443716062 0.8482579123718994 0.9664313956999369 0.9441929120598791 1.2416475268845821 0.8742921011244981 1.0 16.63596680094122 MITNSLNHDS(ph)PPSTPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MITNSLNHDSPPSTPPR 17 0 J3QKZ5;J3QS16;Q8N9M1-2;Q8N9M1;Q8N9M1-3 J3QKZ5 C19orf47 Uncharacterized protein C19orf47 1 MIT(0.024)NS(0.029)LNHDS(0.919)PPS(0.012)T(0.016)PPR 57.227 0.03207 3881300.0 5676.0 9577.9 15777.0 17934.0 16274.0 14737.0 15193.0 12253.0 12182.0 9278.2 True False 6636.834693889931 10528.730613864078 16153.183514605696 16929.21612281248 13085.226523886486 13964.165776994201 13753.809052205406 11931.371733126636 12360.138703920233 10960.264213809218 0.6055360130395353 0.9606274455134544 1.4737950837219544 1.544599271747735 1.193878748598045 1.2740720026986452 1.2548793335544324 1.0886025647168145 1.127722695621449 1.0 13.41999495662141 -4.953670001853239 3.598546325772906 1.2577655463386692 0.6210772924104941 0.6134742385542253 0.1582477895855848 0.16075889109822084 4.125124109313839 0.04305970661619825 0.21692203853821893 1.1125767963371377e-05 4.953670001853239 -0.6366882539281751 MITNSLNHDS(ph)PPSTPPR ddPTM_PC-9_Lapatinib_30min_R1 1 MITNSLNHDSPPSTPPR 17 0 J3QKZ5;J3QS16;Q8N9M1-2;Q8N9M1;Q8N9M1-3 J3QKZ5 C19orf47 Uncharacterized protein C19orf47 1 MITNSLNHDS(0.979)PPS(0.015)T(0.006)PPR 68.42 0.012101 4846900.0 8637.4 6651.6 14411.0 9544.2 12197.0 16323.0 8533.9 8316.0 14170.0 8221.7 True False 8514.229092094829 6636.198628873082 13226.183208068689 10246.11230651786 11479.596440224635 15624.903340771474 8975.743585306607 8702.391719050569 12574.025383284932 9642.809890273376 0.8829614177795896 0.6882017487005485 1.371610905801413 1.0625650016032184 1.1904825015583902 1.6203682866891513 0.9308224145702972 0.9024746747137057 1.3039793925594498 1.0 13.235237890045727 -5.25216556804588 24.941383639126414 1.1733436592304811 0.7855815557914068 0.3477297099258714 0.21212557124976825 721.4030186968874 1940161.0844070276 0.05512986675096697 0.14155295149637645 5.5954424325011475e-06 5.25216556804588 -0.38776210343907436 MIYASSK ddPTM_PC-9_Lapatinib_30min_R1 1 MIYASSK 7 0 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;Q9Y281-3;P60981;F6RFD5;P60981-2;Q9Y281 P23528;P60981;Q9Y281 CFL1;CFL2;DSTN Cofilin-1;Cofilin-2;Destrin 0 107.32 0.04573 25405000.0 177210.0 175060.0 175270.0 181230.0 192670.0 140750.0 190680.0 135360.0 157270.0 164140.0 False True 174682.95290366586 174654.6593256546 160859.97716176574 194558.2587655572 181337.5294037944 134730.4506042752 200552.4773955947 141649.3197559749 139556.59647348052 192511.3802971979 0.907390267702571 0.9072432967652291 0.8355868464162018 1.0106325063235189 0.9419574527170634 0.699857070248414 1.0417694636336978 0.7357971229404596 0.7249264758168265 1.0 17.55458420758481 MIYSYSSHS(ph)VS(ph)SIALSPASLDSMS(ph)GNVTMTNPSSSGK ddPTM_PC-9_Lapatinib_30min_R1 1 MIYSYSSHSVSSIALSPASLDSMSGNVTMTNPSSSGK 37 0 Q5T6X5-2;Q5T6X5-3;Q5T6X5 Q5T6X5-2 GPRC6A G-protein coupled receptor family C group 6 member A 3 MIY(0.037)S(0.142)Y(0.137)S(0.141)S(0.141)HS(0.325)VS(0.325)S(0.194)IALS(0.225)PAS(0.253)LDS(0.253)MS(0.453)GNVT(0.113)MT(0.112)NPS(0.049)S(0.049)S(0.049)GK 40.545 0.0093286 962450000.0 157150.0 250010.0 91122.0 197340.0 226350.0 172880.0 199510.0 232350.0 157560.0 204170.0 True False 154909.01218221986 249431.1172055689 83630.300901092 211853.0419069419 213036.53802122225 165486.3254029632 209839.6515900728 243145.82923537766 139813.9336196453 239460.51246057567 0.6469083799681744 1.0416377825410141 0.34924464180648884 0.8847097157274353 0.8896520592567269 0.6910798097878813 0.8763016893009465 1.0153900813830787 0.5838705187046821 1.0 17.86942824658133 MKDCEYQQISPGAAPLPAS(ph)PGAR ddPTM_PC-9_AZD4547_30min_R2 1 MKDCEYQQISPGAAPLPASPGAR 23 1 Q9NUE0 Q9NUE0 ZDHHC18 Palmitoyltransferase ZDHHC18 1 MKDCEYQQIS(0.002)PGAAPLPAS(0.998)PGAR 75.887 0.00056304 4496700.0 15476.0 30923.0 32710.0 40274.0 34316.0 26936.0 33559.0 48027.0 31029.0 32579.0 True False 20397.046079202744 40918.255017776486 32276.244027665663 30989.451527097328 29551.81573727701 25251.68766187691 36545.68598760264 40605.53070066798 32669.129593040994 31438.419126275843 0.6487936304072982 1.3015366597609075 1.0266497147335751 0.9857191420034452 0.9399905134726692 0.8032111144154783 1.1624530432275524 1.2915894573951519 1.0391467033320558 1.0 14.940241053379307 -7.307989723913888 24.920806128389113 1.1475965291032038 0.971436206484943 0.18114601316390633 0.17323579075326925 696.617247771332 372932.585804452 0.07122477053082193 0.048019901264625894 4.9205117824351334e-08 7.307989723913888 -0.17616032261826076 MKDTDSEEEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MKDTDSEEEIR 11 1 P0DP25;P0DP24;P0DP23;E7EMB3;G3V361;A0A590UJI2;Q96HY3;A0A590UJC0;G3V226 P0DP25 CALM2;CALM1 0 92.943 0.044577 9128400.0 39508.0 48352.0 64824.0 61463.0 71331.0 35132.0 57085.0 48876.0 37588.0 39271.0 False True 46195.924081431156 53152.06701276432 66369.65000638909 58019.42737573459 57354.20260386795 33289.61607364866 51677.495540390024 47593.056788402646 38137.65339049035 46390.52143093505 0.9958052347009377 1.145752739423196 1.4306726451695186 1.2506741805459622 1.2363345104722596 0.7175952122721738 1.1139666885901698 1.025922005624746 0.8221001233467197 1.0 15.501542441766437 -6.7239057469596615 24.998671185406966 0.9486649403440671 1.2224901171788198 0.4772986082132443 0.14385451145840786 154.48676865432486 102892.99751078206 0.04865059432524695 0.048649477981010956 1.8884011361033547e-07 6.7239057469596615 0.2738251768347527 MKEIAEAYLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MKEIAEAYLGK 11 1 P11142;E9PKE3;P11142-2;E9PN89;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65;E9PPY6 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 70.41199999999999 0.038087 0.0 59149.0 45211.0 58873.0 72773.0 71116.0 68095.0 69037.0 83313.0 74044.0 64811.0 False True 69161.75745399857 49699.24929091016 60276.75559709581 68695.76474324938 57181.33031047748 64523.97832560352 62497.3155754035 81126.12202742013 75126.75342251443 76560.72125640628 0.9033582275481946 0.6491481333419588 0.7873065275237608 0.8972716507356729 0.7468755436482096 0.8427817458708231 0.8163104337287573 1.059631109739994 0.9812701890687602 1.0 16.224316800650023 -7.74774346512978 17.882926511674732 1.0153375617604201 0.8020188686474619 0.6381311582261169 0.07154933095383996 4.554168100106285 5947.29646524573 0.03363611457654856 0.0191120137764437 1.787543152945331e-08 7.74774346512978 -0.21331869311295826 MKETIQGTGSWGPEPPGPGIPPAYS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MKETIQGTGSWGPEPPGPGIPPAYSSPR 28 1 Q9H4L4 Q9H4L4 SENP3 Sentrin-specific protease 3 1 MKETIQGTGSWGPEPPGPGIPPAY(0.008)S(0.496)S(0.496)PR 86.022 6.3827e-07 7451300.0 7902.5 6714.4 5774.2 7516.4 10953.0 9985.8 13229.0 11509.0 12367.0 11909.0 True False 9240.237168510424 7380.961258076293 5911.878826775446 7095.280476497587 8806.83827676839 9462.127069003776 11975.853350334055 11206.900944793475 12547.843978934608 14068.007428407866 0.6568262929582616 0.5246628774997475 0.42023569129182053 0.5043557527677954 0.6260188816068245 0.672598953132245 0.8512828423839844 0.7966231893056234 0.8919418078779547 1.0 13.78013038141976 -7.191869334111641 0.9040872732180429 0.9304132196724629 0.5143710981071811 0.8495274533339852 0.06875196054484445 0.22881305945959554 0.3701430458370581 0.05442138018806216 0.03345247218362527 6.428811114295252e-08 7.191869334111641 -0.41604212156528186 MKGT(ph)ASGSS(ph)RS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MKGTASGSSRSK 12 2 A0A087WWP5;Q12962 A0A087WWP5 TAF10 Transcription initiation factor TFIID subunit 10 3 MKGT(0.999)AS(0.067)GS(0.232)S(0.851)RS(0.851)K 68.171 0.026805000000000002 0.0 656.46 1068.4 8986.4 2824.3 4758.2 2457.8 2229.7 1041.9 2840.7 1030.5 True False 767.5857123239925 1174.4636911903833 9200.669857111783 2666.063627504144 3825.864867024499 2328.9086412903803 2018.486674369932 1014.5512289843011 2882.239863423592 1217.321492566488 0.6305529944318045 0.9647933585024058 7.558126520639952 2.1901064293897106 3.1428549404466684 1.913141808069391 1.6581377119320728 0.8334291599874042 2.367689949634377 1.0 10.249494516378054 -6.905229119239497 2.6252965388109195 1.4569678245249764 3.023102513794913 0.1217999271170419 1.8096996424647027 0.6254031835061734 8.742763063348322 0.7458436455079371 0.6344150102259092 1.243858220657194e-07 6.905229119239497 1.5661346892699366 MKKFS(ph)RMPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MKKFSRMPK 9 3 K4DI97;Q9NSY1-2;Q9NSY1-3;Q9NSY1 K4DI97 BMP2K BMP-2-inducible protein kinase 1 MKKFS(1)RMPK 41.70399999999999 0.045939 0.0 2606.5 1049.4 2067.1 1170.8 3055.9 2521.3 3005.4 3369.2 2888.7 842.28 True False 3047.7289692783816 1153.5774967570098 2116.3875035204037 1105.2038717848138 2457.1183319617007 2389.078589505019 2720.706754788266 3280.7620699624817 2930.941772616514 994.978696515189 3.0631097730561874 1.1593991919598852 2.1270681582759856 1.1107814425129676 2.469518533982191 2.4011354191527134 2.7344371937984833 3.2973189088902255 2.9457331929636656 1.0 9.958521826224061 -6.492907572222297 21.675403628228413 2.6132385561240836 1.8279893722187384 0.11981447591018124 0.7626994605167634 218.20705716309982 157808.50889598537 0.22620606435254084 0.25583654458056215 3.21434455173291e-07 6.492907572222297 -0.7852491839053453 MKPPAACAGDMADAAS(ph)PCSVVNDLR ddPTM_PC-9_AZD4547_30min_R2 2 MKPPAACAGDMADAASPCSVVNDLR 25 1 P52888 P52888 THOP1 Thimet oligopeptidase 1 MKPPAACAGDMADAAS(0.983)PCS(0.017)VVNDLR;MKPPAACAGDMADAAS(0.775)PCS(0.225)VVNDLR 64.592 0.00044896 13856000.0 31450.2 26905.0 40520.0 53458.0 45086.0 39710.0 39170.0 46265.0 31185.0 40548.0 True False 41450.709395201724 35601.51509404897 39982.678324702334 41134.08401786679 38826.58714100916 37226.92742252496 42656.05411765535 39115.807313936 32833.37543456069 39128.42686185066 1.059350265768421 0.9098631851402043 1.0218319909938558 1.0512583131209807 0.9922859224086059 0.9514036317882327 1.090155100491506 0.9996774838927407 0.8391182081120796 1.0 15.255929488146723 -8.039732836275567 23.818997325752147 0.919505196312546 1.0087471681896891 0.2579220609259818 0.06119241140366413 404.7895721024658 242659.3399531987 0.03945761533398079 0.014920339522380553 9.125720511206182e-09 8.039732836275567 0.08924197187714311 MKPPAACAGDMADAAS(ph)PCSVVNDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MKPPAACAGDMADAASPCSVVNDLR 25 1 P52888 P52888 THOP1 Thimet oligopeptidase 1 MKPPAACAGDMADAAS(0.66)PCS(0.34)VVNDLR;MKPPAACAGDMADAAS(0.956)PCS(0.044)VVNDLR 71.86399999999999 0.00017477 28827000.0 42238.0 39150.0 52121.0 63866.0 62636.0 53830.0 53966.0 42463.0 51403.0 51478.0 True False 49388.05916147336 43036.553266663745 53363.76230999325 60287.79507636569 50362.92543628823 51007.06003770084 48853.949799994545 41348.39124326749 52154.671630078126 60810.553900376246 0.8121626262833265 0.7077151991933668 0.8775411320445657 0.991403485242595 0.8281938283080928 0.8387863087263417 0.8033794574545435 0.6799541953031225 0.8576582235301007 1.0 15.892034110099699 -12.029397507947362 1.829849583528975 2.5119579974657285 0.8210986820371488 0.2986308233286734 0.08189056577877002 3467962.2861826443 220669.30334983591 21704408.780365165 0.022152211070723123 9.345498928998106e-13 12.029397507947362 -1.6908593154285798 MKPPAACAGDMADAAS(ph)PCSVVNDLR ddPTM_PC-9_Lapatinib_30min_R1 1 MKPPAACAGDMADAASPCSVVNDLR 25 1 P52888 P52888 THOP1 Thimet oligopeptidase 1 MKPPAACAGDMADAAS(0.974)PCS(0.026)VVNDLR 63.202 0.00073093 12361000.0 55056.0 58328.0 79212.0 61881.0 64528.0 72278.0 63470.0 53732.0 75035.0 52608.0 True False 54270.89134396617 58192.94509966162 72699.49512716236 66431.93516896467 60732.589906929155 69186.83842824724 66756.16603890488 56228.584878309906 66583.76814642084 61701.22270424631 0.8795756220926756 0.9431408738624032 1.1782504777196114 1.0766712920324801 0.9843012382111109 1.1213203790122908 1.0819261452708728 0.9113042240318557 1.0791320694822877 1.0 15.913011458419676 -5.0190407945006745 19.077847157214013 1.0531879509322324 0.8954653350208872 0.4059535667066989 0.07091609410993657 29.656638561185684 29720.862908575084 0.018221992784020258 0.05085897854532133 9.571041635895536e-06 5.0190407945006745 -0.15772261591134518 MKS(ph)SSSVTTSETQPCTPSSSDYSDLQR ddPTM_PC-9_AZD4547_30min_R2 1 MKSSSSVTTSETQPCTPSSSDYSDLQR 27 1 K7EM16;P50552 K7EM16 VASP Vasodilator-stimulated phosphoprotein 1 MKS(0.135)S(0.135)S(0.135)S(0.135)VT(0.135)T(0.135)S(0.135)ET(0.055)QPCTPSSSDYSDLQR 85.42299999999999 1.3122e-06 20451000.0 15815.0 12593.0 18780.0 20123.0 21909.0 22758.0 12743.0 20041.0 12450.0 17312.0 True False 20843.841027564707 16663.440980463056 18530.964929365997 15483.953247250807 18867.313526867987 21334.93866234761 13877.102313537962 16944.123946365307 13108.081582821242 16705.912149362703 1.2476924840263726 0.9974577162551841 1.1092459222630904 0.926854703222026 1.1293794291614145 1.2770891210008843 0.8306701357858718 1.0142591314304075 0.784637286825508 1.0 14.028071136088581 -7.280936111644611 24.995910496429335 0.9085798972302145 1.1011861907486078 0.4296435946662578 0.11635045656923408 875.5666744446415 1122521.3061664645 0.04791824835379547 0.03235941172826794 5.236774682608496e-08 7.280936111644611 0.1926062935183933 MKS(ph)SSSVTTSETQPCTPSSSDYSDLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MKSSSSVTTSETQPCTPSSSDYSDLQR 27 1 K7EM16;P50552 K7EM16 VASP Vasodilator-stimulated phosphoprotein 1 MKS(0.143)S(0.143)S(0.143)S(0.143)VT(0.143)T(0.143)S(0.143)ET(0.002)QPCTPSSSDYSDLQR;MKS(0.219)S(0.219)S(0.219)S(0.219)VT(0.034)T(0.034)S(0.053)ET(0.005)QPCTPSSSDYSDLQR 121.35 4.306999999999999e-12 39654000.0 37389.0 25630.0 31763.0 40898.0 45022.0 45846.0 40600.0 40956.0 39823.0 38610.0 True False 43718.21923358889 28174.377017230934 32520.350381848304 38606.61765310498 36200.26229313122 43441.755052729575 36754.07408145461 39880.94839646902 40405.33603728579 45609.687363408186 0.9585292458869871 0.6177279136500883 0.7130141042786183 0.8464565289714825 0.7936967864895743 0.9524677226264457 0.8058392022862609 0.8743964429904155 0.8858937294470967 1.0 15.477052660668019 -6.298027232663131 1.6516299992699468 0.8881470172528816 0.7556890605359834 0.24476316503135231 0.09686614845898188 0.5232904054108413 2.831463494822904 0.03442195569496568 0.04495189309454105 5.034690375081693e-07 6.298027232663131 -0.1324579567168982 MKSSSSVT(ph)TSETQPCTPSSSDYSDLQR ddPTM_PC-9_Lapatinib_30min_R1 1 MKSSSSVTTSETQPCTPSSSDYSDLQR 27 1 K7EM16;P50552 K7EM16 VASP Vasodilator-stimulated phosphoprotein 1 MKS(0.059)S(0.059)S(0.059)S(0.059)VT(0.228)T(0.228)S(0.228)ET(0.08)QPCTPSSSDYSDLQR 63.559 0.00042747 14088000.0 11060.0 8542.2 9836.3 11164.0 10245.0 11085.0 9113.7 12205.0 13916.0 14188.0 True False 10902.282371844403 8522.421060731207 9027.597383216022 11985.037802012257 9642.409242444977 10610.920390397085 9585.56279232342 12772.088856543076 12348.633538023507 16640.37689567834 0.6551703990956976 0.5121531269489791 0.5425115933257841 0.7202383622167166 0.5794585845558102 0.6376610612198838 0.5760424089200096 0.7675360321832678 0.7420885725990114 1.0 14.022400489673181 -8.684874928791984 0.6484324478372496 1.0050611420203441 0.5905989441900814 0.7819064994695258 0.0636029674778602 0.43748871319325455 0.40017315196935294 0.06609363896243342 0.025973120489950964 2.065975044306216e-09 8.684874928791984 -0.4144621978302627 MKSSSSVTT(ph)SETQPCTPSSSDYSDLQR ddPTM_PC-9_Lapatinib_30min_R1 1 MKSSSSVTTSETQPCTPSSSDYSDLQR 27 1 K7EM16;P50552 K7EM16 VASP Vasodilator-stimulated phosphoprotein 1 MKS(0.132)S(0.132)S(0.132)S(0.132)VT(0.049)T(0.242)S(0.065)ET(0.115)QPCTPSSSDYSDLQR 80.02 1.5993e-05 17177000.0 4980.7 3940.9 3873.3 3074.9 4113.8 4124.6 3990.5 5222.3 6781.1 5520.5 True False 4909.674304651484 3931.7750881781726 3554.8522253703773 3301.038403565702 3871.834372041983 3948.20047291221 4197.108564333545 5464.947122943454 6017.34110985134 6474.711069396135 0.758284694410215 0.6072510488942745 0.5490364260689583 0.5098356309934265 0.5979933823368415 0.6097879010499907 0.6482310205581094 0.844044941059145 0.9293605607041471 1.0 12.660600099384085 -7.911135410999048 1.6012527181371303 0.9844462240144181 0.595549909894281 0.852020756225234 0.0614576098068367 0.14696958214225658 0.6877331904774722 0.055062111349696255 0.019336754173134085 1.2270565809737554e-08 7.911135410999048 -0.38889631412013703 MKSSSSVTTSET(ph)QPCTPSSSDYSDLQR ddPTM_PC-9_AZD4547_30min_R2 2 MKSSSSVTTSETQPCTPSSSDYSDLQR 27 1 K7EM16;P50552 K7EM16 VASP Vasodilator-stimulated phosphoprotein 1 MKS(0.099)S(0.099)S(0.099)S(0.099)VT(0.099)T(0.099)S(0.099)ET(0.308)QPCTPSSSDYSDLQR;MKS(0.088)S(0.088)S(0.088)S(0.088)VT(0.088)T(0.088)S(0.088)ET(0.384)QPCT(0.002)PSSSDYSDLQR 52.059 0.0078998 32746700.0 8741.2 9075.25 16483.7 22831.0 22986.3 24469.03 15407.1 19289.8 16239.02 20048.3 True False 11520.719771745087 12008.647086313616 16265.115367741757 17567.665685433753 19795.049017419573 22938.977685962895 16778.302052492407 16309.004645506588 17097.381444583618 19346.415119227597 0.5954963594415548 0.6207169138213479 0.8407301956204039 0.9080579310000425 1.023189510585147 1.185696551252268 0.8672563856968597 0.8429987956423899 0.8837493323293389 1.0 14.239778640035043 -5.393015149924846 1.8988662266594676 0.9629013375153922 0.5820755865509591 0.6915969296783171 0.09297525771725815 0.23408912262687154 1.5721524474482107 0.03030242450813809 0.0994447764144355 4.0456177872179315e-06 5.393015149924846 -0.38082575096443305 MKTPVQYSQQQNS(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 1 MKTPVQYSQQQNSPQK 16 1 P46013 P46013 MKI67 Antigen KI-67 1 MKTPVQYSQQQNS(1)PQK 123.43 6.311600000000001e-05 9744200.0 38259.0 53684.0 54939.0 91097.0 74175.0 41020.0 32389.0 40140.0 27548.0 52927.0 True False 50424.5661633638 71036.30315216228 54210.47296349506 70095.99408462002 63877.08160369869 38455.01291543625 35271.55825419299 33937.28532543801 29004.131039643362 51074.041839725 0.9872836444313666 1.3908494529389444 1.0614094951328203 1.3724387489164778 1.2506760636675434 0.7529267614282729 0.6905965728124348 0.664472285783379 0.567883997328055 1.0 15.640302613485074 -6.785135435010988 6.2357232401645435 0.7081278300451453 1.2237689915838146 0.7010963411002455 0.15535798283750385 0.08512811247748839 10.872651314355906 0.05129410935755747 0.04657081226087049 1.6400782339991635e-07 6.785135435010988 0.5156411615386692 MLAEDELR ddPTM_PC-9_Lapatinib_30min_R1 3 MLAEDELR 8 0 P61204-2;P84077;P61204;F5H423 P61204-2 ARF3;ARF1 ADP-ribosylation factor 3;ADP-ribosylation factor 1 0 ;; 148.04 0.0044831 7630700.0 47953.4 59687.2 66532.0 54925.5 70786.1 68050.4 64650.3 65576.9 59102.9 52360.2 False True 47269.575722423455 59548.99795557062 61061.995780946956 58964.90449609674 66622.60076882708 65140.04302523025 67997.5761976527 68623.84217424341 52446.10902087162 61410.590804419066 0.7697300270724959 0.9696861270268957 0.9943235357467523 0.9601748448225914 1.0848715163970213 1.0607297889819816 1.1072613910231204 1.117459403587195 0.8540238472530317 1.0 15.906199862236317 -4.033626810886826 0.9779830161314913 1.0391393129225786 2.214366183653313e-15 0.5054016424956952 0.07455907681945424 5.826826776724329 1.549640115826228 0.024071468606857042 9.070200714104935 9.25493108285883e-05 4.033626810886826 -1.0391393129225763 MLCVIYHLDNPVGKMSS(ph)S(ph)PLSK ddPTM_PC-9_Lapatinib_30min_R1 1 MLCVIYHLDNPVGKMSSSPLSK 22 1 Q5JRS0;Q5JRS1 Q5JRS0 UBA1 2 MLCVIY(0.008)HLDNPVGKMS(0.481)S(0.522)S(0.556)PLS(0.434)K 55.06100000000001 0.039226 0.0 11915.0 9864.2 6586.2 8544.5 4760.2 8043.4 7213.8 8919.3 6454.0 10856.0 True False 11745.089915056613 9841.36005095464 6044.708059467219 9172.891033616424 4480.214394913279 7699.402532081186 7587.295266605517 9333.7232395055 5727.082556367039 12732.445135289272 0.9224536049642105 0.7729355945684231 0.47474840812105235 0.7204343656029446 0.3518738425580101 0.6047073009363697 0.5959024512563226 0.7330660482200809 0.44980225679463914 1.0 13.636221880156848 -10.336705934192024 6.987343049690579 1.0000000019491924 0.6215129303038001 0.3267513509903335 0.16136654090019162 4.965056707285968e-09 1.0015967069340354e-09 0.15655378801138772 0.03796987082714754 4.6056832415440626e-11 10.336705934192024 -0.3784870716453923 MLDAEDIVNTARPDEK ddPTM_PC-9_AZD4547_30min_R2 2 MLDAEDIVNTARPDEK 16 1 O43707 O43707 ACTN4 Alpha-actinin-4 0 ; 141.59 0.00014572 50665000.0 94702.0 90898.0 149045.0 166098.0 155030.0 126880.0 117395.0 137018.0 138395.0 145854.0 False True 124815.26607603116 120279.00089272845 147068.56591572714 127806.672288519 133506.76051259035 118946.17354243198 127842.92757575077 115845.01646041016 145710.27716100786 140747.69585450224 0.8868014877135807 0.854571722559968 1.0449092258516197 0.9080551657530436 0.9485537912507129 0.8451021014609891 0.9083127563800991 0.8230686531462995 1.035258703713599 1.0 17.1027517789342 -8.28464317337476 24.750242051638548 1.0176293979364666 0.9055876457051643 0.374636561192877 0.05942653562054984 886.0166654025425 945055.9228969426 0.05751489413496666 0.014889783288781941 5.192264724798952e-09 8.28464317337476 -0.1120417522313023 MLDAEDIVNTARPDEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MLDAEDIVNTARPDEK 16 1 O43707 O43707 ACTN4 Alpha-actinin-4 0 86.539 0.026974 21358000.0 70548.0 76026.0 75346.0 80007.0 111600.0 88799.0 85521.0 98896.0 77169.0 64764.0 False True 82490.38301348589 83573.35884166988 77142.53439129614 75524.46717619381 89732.78112730331 84142.2241182947 77419.8317615782 96300.08478897344 78297.45063559497 76505.2005284581 1.0782323612471474 1.0923879457133452 1.0083305952854926 0.9871808276366849 1.172897796587369 1.0998235876395857 1.0119551511113272 1.2587390677206594 1.0234265134233613 1.0 16.223270199532593 -6.253388520335318 24.812461502488443 1.1035522084794311 1.042793843756034 0.09067296879082609 0.07901574149630003 1247.9584442282426 3846162.526795621 0.022879221156344172 0.028984356800807676 5.579708100765382e-07 6.253388520335318 -0.06075836472339713 MLDAEDIVNTARPDEK ddPTM_PC-9_Lapatinib_30min_R1 2 MLDAEDIVNTARPDEK 16 1 O43707 O43707 ACTN4 Alpha-actinin-4 0 ; 119.62 0.00063988 59007300.0 149772.0 143610.0 172758.0 167711.0 151850.0 139140.0 148707.0 127828.0 184523.0 164741.0 False True 147636.22381517908 143277.47986837206 158554.50410516528 180045.026407495 142918.48154858637 133189.30655118206 156406.32083106058 133767.35553905688 163740.0766266679 193216.2623464156 0.7640983322122415 0.7415394446016724 0.8206064136614671 0.9318316389160555 0.7396814316403098 0.6893276214627743 0.8094883884599795 0.6923193416257408 0.8474445920763122 1.0 17.55985700038668 -8.538256305924515 21.494753874799745 1.000000004661557 0.7762161352184054 0.5166448386135403 0.06675785327274884 330.0067830306094 461284.7013524735 0.06755452886670858 0.017442504329925005 2.8956341779106368e-09 8.538256305924515 -0.22378386944315154 MLDGLDPHPMLPNY(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 MLDGLDPHPMLPNYK 15 0 Q02880;Q02880-2;E9PCY5 Q02880 TOP2B DNA topoisomerase 2-beta;DNA topoisomerase 2 1 MLDGLDPHPMLPNY(1)K 80.96 0.010413 2412600.0 7115.2 6688.9 9348.4 13292.0 9895.0 8564.7 5025.9 9274.8 8838.5 8422.4 True False 9377.685594646118 8850.956116431296 9224.434107863948 10227.734759352872 8521.250050132769 8029.147955066721 5473.1953635415875 7841.59277370136 9305.685065844624 8127.534339579044 1.153816791518081 1.0890087628826581 1.1349609515573842 1.2584056039660616 1.0484422081905491 0.987894682396701 0.6734139943141803 0.9648181657645886 1.1449579512113879 1.0 12.988602031109645 -6.6343496013281 3.0892591404197436 0.932934967204695 1.1522184842232155 0.39726097874850985 0.11702344863092615 0.26098097923020985 4.983012205365208 0.04325223296327027 0.043133557682545405 2.320867776250089e-07 6.6343496013281 0.21928351701852045 MLDMGFEPQIR ddPTM_PC-9_Lapatinib_30min_R1 1 MLDMGFEPQIR 11 0 P17844-2;P17844;J3KTA4;J3QSF1;J3KRZ1;A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2;A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDT5;A0A2R8YDH3;A0A2R8Y7T2;O15523-2;O15523 P17844-2;A0A1X7SBZ2;A0A2R8Y5G6 DDX5;DDX17;DDX3X;DDX3Y Probable ATP-dependent RNA helicase DDX5;Probable ATP-dependent RNA helicase DDX17;ATP-dependent RNA helicase DDX3X;ATP-dependent RNA helicase DDX3Y 0 140.17 0.00054597 2678700.0 11068.0 10146.0 11240.0 10238.0 9609.6 11995.0 10021.0 9316.4 11544.0 10081.0 False True 10910.168290377385 10122.507560368385 10315.890587654716 10990.936672966816 9044.382221200507 11482.001811710696 10539.838346870421 9749.273955190316 10243.79315629084 11823.487417911854 0.922753829284679 0.8561355209828709 0.8724913575014067 0.9295850102835332 0.7649504669408136 0.9711180302282194 0.8914322800312889 0.824568387531818 0.8663935431412668 1.0 13.529368010534336 MLDQTLLDLNEM ddPTM_PC-9_Lapatinib_30min_R1 1 MLDQTLLDLNEM 12 0 A0A087WWU8;P06753-5;P06753-2;P06753-7;J3KN67 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 163.38 1.0373e-12 0.0 5995.4 7615.4 8236.7 7518.1 7507.3 8680.3 7078.5 7385.0 9330.0 6835.3 False True 5909.904496578297 7597.767009188785 7559.510320581461 8071.006153646394 7065.735373919684 8309.063803767598 7444.990094633501 7728.134060267968 8279.157150744417 8016.772497535254 0.7371924921650563 0.9477338931003354 0.9429618119892541 1.0067650237209318 0.8813690766567263 1.0364599726788066 0.9286767333016439 0.9639956806363126 1.0327294622979302 1.0 12.96880581822837 -4.7318403158002 3.2912608491749595 0.9704670323363409 0.6885717749580029 0.7034187838376387 0.04578963151955115 0.2200104759503508 3.320214284298451 0.01092946329088774 0.1695017732731918 1.8542132672002155e-05 4.7318403158002 -0.281895257378338 MLENTDNSS(ph)PSTEHSQGLEK ddPTM_PC-9_Lapatinib_30min_R1 1 MLENTDNSSPSTEHSQGLEK 20 0 Q96H79 Q96H79 ZC3HAV1L Zinc finger CCCH-type antiviral protein 1-like 1 MLENT(0.238)DNS(0.172)S(0.581)PS(0.003)T(0.006)EHSQGLEK 62.001999999999995 0.036708 0.0 30533.0 26471.0 28706.0 28239.0 30424.0 38115.0 26401.0 29633.0 31375.0 19713.0 True False 30097.59382093356 26409.708025873377 26345.903488364456 30315.790262542458 28634.520135885406 36484.910300404634 27767.914598914886 31009.857360585083 27841.217106603006 23120.365784078615 1.3017784451169747 1.142270337438169 1.1395106692692138 1.3112158581599445 1.2384977125060888 1.578042088137258 1.2010153670681418 1.3412355864170373 1.204185840596662 1.0 14.496876602245385 -8.595551407729628 6.004753868656438 1.0000056604899175 1.2788257303612174 0.33961607700263374 0.11863703451973322 0.92449449399315 75.16631927102806 0.11800595632896452 0.0305848361203602 2.537748573180362e-09 8.595551407729628 0.2788200698712999 MLENY(ph)S(ph)HLIS(ph)VGY(ph)CITK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MLENYSHLISVGYCITK 17 0 A0A087X186 A0A087X186 ZNF658 4 MLENY(0.999)S(0.999)HLIS(0.917)VGY(0.922)CIT(0.162)K 43.023999999999994 0.044579 0.0 10495.0 14913.0 13584.0 13060.0 12654.0 16011.0 16298.0 12095.0 13131.0 12299.0 True False 12271.596214301404 16393.4640834165 13907.89407760688 12328.290541091283 10174.539537499062 15171.35497424537 14754.135452698192 11777.519065711807 13323.016033588616 14528.711341169561 0.844644506049739 1.12834949352754 0.9572696263980763 0.848546732851453 0.7003057118127045 1.044232665787417 1.015515767794894 0.8106375568449912 0.9170129215683153 1.0 13.826619124904777 -5.528177276413186 23.714928029105824 0.8994331324776309 1.0005751290495661 0.07312499731764888 0.11646084487208046 156.14384449957902 698858.449049416 0.03200895186238 0.05572439102432837 2.96362141003203e-06 5.528177276413186 0.10114199657193523 MLFKDDYPS(ph)SPPK ddPTM_PC-9_AZD4547_30min_R2 1 MLFKDDYPSSPPK 13 1 H3BPC4;H3BQQ9;B0QYN7;P63279 H3BPC4 UBE2I SUMO-conjugating enzyme UBC9 1 MLFKDDYPS(0.5)S(0.5)PPK 66.387 0.01772 5090300.0 59279.0 44445.0 46706.0 44852.0 57953.0 44285.0 50171.0 45083.0 43952.0 55209.0 True False 78128.48892020292 58810.9770806544 46086.647922841716 34512.064356492265 49907.22629159619 41515.85194929535 54636.12180589447 38116.458254278084 46275.21299021361 53276.14971431174 1.4664815182621018 1.1038894025942685 0.8650521512905298 0.6477957686799799 0.9367648855861191 0.7792577386301401 1.0255268464195602 0.7154506933904562 0.8685915412123439 1.0 15.701202201658571 -4.8841570397237914 2.1461064728918253 0.843205373283555 1.5587663033579955 0.739221350479919 0.11273096411708665 0.24609045124252094 1.5585904906207984 0.029140002265277812 0.31763377461286463 1.3056986656124203e-05 4.8841570397237914 0.7155609300744404 MLFKDDYPSS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 2 MLFKDDYPSSPPK 13 1 H3BPC4;H3BQQ9;B0QYN7;P63279 H3BPC4 UBE2I SUMO-conjugating enzyme UBC9 1 MLFKDDY(0.01)PS(0.201)S(0.789)PPK;MLFKDDY(0.005)PS(0.343)S(0.652)PPK 80.361 0.0060592 10300600.0 176528.0 137044.0 126637.0 136331.0 150869.0 131562.0 124770.0 122231.0 122494.0 102811.0 True False 174010.67834872933 136726.6830379586 116225.39469295634 146357.23652688405 141995.1820398664 125935.39994600113 131229.98009570135 127910.2984862037 108697.43580099528 120581.74436295388 1.4430930591363242 1.133892064344401 0.9638722288103179 1.2137594898805357 1.1775844079055415 1.044398558101238 1.0883071959939146 1.0607766470950255 0.9014418921807389 1.0 16.879651979430854 -4.780914621359932 3.771946019974963 1.0679363208537784 1.4817446908037084 0.630554119452063 0.08818035915090913 0.17047968492120588 4.293444469350967 0.02276486100502019 0.1971953008859253 1.6560955059075933e-05 4.780914621359932 0.41380836994993 MLGY(ph)DIS(ph)WAAFNIIEVMSASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MLGYDISWAAFNIIEVMSASK 21 0 A0A2R8YCY8;A0A2R8Y4J3 A0A2R8YCY8 2 MLGY(0.998)DIS(0.995)WAAFNIIEVMS(0.005)AS(0.002)K 44.586999999999996 0.041894 0.0 4169.0 7260.5 5780.5 7548.6 5607.2 5256.1 5624.1 5135.7 5180.1 4942.8 True False 4874.729358496671 7981.274457027126 5918.329042668328 7125.6764148914 4508.509411621994 4980.460863164766 5091.344533042087 5000.893316723942 5255.849162713608 5838.890512816728 0.83487254090419 1.3669162727932185 1.0136050726892767 1.220381920032598 0.7721517301489959 0.8529806908063003 0.871971228415102 0.8564800634207252 0.9001451818931512 1.0 12.511478543540848 -6.262103272786295 24.99995378670745 0.8671309315467501 1.120560628285281 0.40336966477432323 0.13849724701256752 53.86247476130505 2028271.293821763 0.038950398095106996 0.046869529484168296 5.468859010377931e-07 6.262103272786295 0.2534296967385308 MLIS(ph)AVSPEIR ddPTM_PC-9_AZD4547_30min_R2 1 MLISAVSPEIR 11 0 A0AVK6;E9PMT9 A0AVK6 E2F8 Transcription factor E2F8 1 MLIS(0.642)AVS(0.358)PEIR 66.262 0.042637 1335100.0 4001.5 3701.8 5129.4 7920.0 7719.0 8404.6 5461.0 7640.6 6934.7 7760.0 True False 5273.893763629474 4898.334457355524 5061.380804509577 6094.166362780224 6647.350089638689 7879.059033375807 5947.0184206412005 6459.920833521223 7301.254084529356 7488.324761960175 0.7042821901128334 0.65412954339781 0.675902950980546 0.8138223910557252 0.8876952190170035 1.0521791300239163 0.7941720758228018 0.8626656881038166 0.9750183541209221 1.0 12.870427289336256 -5.9823157349325236 2.2849671309469373 0.9218227113028993 0.6726327457793565 0.7232377988359852 0.06945068457765627 0.16684527675079042 1.7537361778708713 0.022230500520064367 0.0348130299672291 1.0415599331817508e-06 5.9823157349325236 -0.24918996552354278 MLIS(ph)AVSPEIR ddPTM_PC-9_Lapatinib_30min_R1 1 MLISAVSPEIR 11 0 A0AVK6;E9PMT9 A0AVK6 E2F8 Transcription factor E2F8 1 MLIS(0.607)AVS(0.393)PEIR 71.153 0.026804 5110900.0 41859.0 35588.0 44649.0 32912.0 45536.0 37759.0 33377.0 37253.0 41865.0 32240.0 True False 41262.08298399956 35505.598172520185 40978.131570124155 35332.45827121349 42857.662007220526 36144.13559052807 35105.09774508473 38983.91037876271 37149.72284200591 37812.64104290032 1.0912245705658505 0.9389875235701552 1.08371513969713 0.9344086341688499 1.1334215443612197 0.9558744005614618 0.9283958162365926 1.030975602432359 0.982468344378741 1.0 15.206580998153322 MLISAVS(ph)PEIR ddPTM_PC-9_AZD4547_30min_R2 3 MLISAVSPEIR 11 0 A0AVK6;E9PMT9 A0AVK6 E2F8 Transcription factor E2F8 1 MLIS(0.064)AVS(0.936)PEIR;MLIS(0.043)AVS(0.957)PEIR;MLIS(0.322)AVS(0.678)PEIR 80.87100000000001 0.013813999999999998 28941300.0 97773.0 108040.0 159032.0 214133.0 162744.0 158957.0 134352.0 166525.0 142473.0 156239.0 True False 128862.78019526269 142961.81716264828 156923.13177033726 164767.94517187093 140149.80476592272 149017.39366160386 146309.06772568906 140792.38761381563 150003.83191560567 150769.12016545053 0.8547027405469481 0.9482168298506041 1.0408174538535044 1.092849417646388 0.9295657135368673 0.988381397318467 0.9704179978309411 0.9338277457566466 0.9949241048232884 1.0 17.201981447167142 -4.849410040790636 3.4461465641470292 0.991860830726105 0.8471983153875746 0.46418208826023577 0.04535378839376672 0.2547942333379367 5.033438224832146 0.012359358871302356 0.08695162002552631 1.4144576837021129e-05 4.849410040790636 -0.14466251533853036 MLISAVS(ph)PEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 MLISAVSPEIR 11 0 A0AVK6;E9PMT9 A0AVK6 E2F8 Transcription factor E2F8 1 MLIS(0.012)AVS(0.988)PEIR;MLIS(0.014)AVS(0.986)PEIR;MLIS(0.179)AVS(0.821)PEIR 97.779 0.0046224 28717200.0 112737.0 119187.0 141330.0 151862.0 175645.0 170759.0 153709.0 159371.0 146232.0 120841.0 True False 131821.1474427532 131019.09768055801 144699.84319700958 143353.66448324674 141228.6231281827 161804.0974359605 139148.57076320917 155187.68011753255 148370.36635623578 142748.51672317032 0.9234502078812603 0.9178315872426264 1.013669679507938 1.0042392577798196 0.9893526487708791 1.1334905689405117 0.9747812023368168 1.0871404038368069 1.039382893511726 1.0 17.12311622929117 -5.317545929565283 0.9655460991072777 1.0438622479227735 0.8902576466702361 0.4776949338585864 0.045613829887050844 0.8208787135886438 1.052928866219714 0.01594943659731039 0.1103817010899823 4.8134234611459995e-06 5.317545929565283 -0.1536046012525374 MLISAVS(ph)PEIR ddPTM_PC-9_Lapatinib_30min_R1 4 MLISAVSPEIR 11 0 A0AVK6;E9PMT9 A0AVK6 E2F8 Transcription factor E2F8 1 MLIS(0.274)AVS(0.726)PEIR;MLIS(0.086)AVS(0.914)PEIR;MLIS(0.009)AVS(0.991)PEIR;MLIS(0.051)AVS(0.949)PEIR 92.792 0.006563899999999999 24117400.0 177980.0 148487.0 169975.0 169241.4 167835.0 148363.0 137910.2 134329.0 173600.0 140631.1 True False 175441.97256246558 148143.18747451395 156000.31162247405 181687.9771287603 157963.27527630577 142017.86034104496 145050.51535620887 140570.41573212374 154047.33991095738 164938.99825583823 1.0636779319487324 0.8981695599043704 0.9458061057246188 1.1015465053749303 0.9577072550864388 0.8610326353550414 0.8794191603566054 0.8522569993670255 0.9339655359856939 1.0 17.331573025052094 -6.559086686200426 7.2128939499254745 0.8956500449411383 0.9955739812672372 0.31803863089166107 0.06599035900587269 0.23265573302504333 35.80852881146359 0.021769044988769894 0.02191295767411645 2.760026893373535e-07 6.559086686200426 0.09992393632609886 MLLADQGQSWK ddPTM_PC-9_Lapatinib_30min_R1 1 MLLADQGQSWK 11 0 P09211;A8MX94;A0A087X2E9 P09211 GSTP1 Glutathione S-transferase P 0 124.67 0.0023030999999999998 4956200.0 45210.0 35536.0 37497.0 35148.0 24956.0 27740.0 28139.0 29784.0 33304.0 31787.0 False True 44565.29710950142 35453.71857532534 34414.14140260577 37732.901170290825 23488.137145383775 26553.62486509835 29595.899734815557 31167.873371837675 29552.95281333247 37281.3405964849 1.195378073762275 0.9509775670102412 0.9230929159733738 1.0121122407773206 0.6300239414566109 0.7122497324466379 0.7938528835415867 0.8360180420866186 0.7927009152701685 1.0 15.186166118219932 -4.343433012871338 0.7462414898179459 0.7975450253044087 1.6806651018599463 0.5145269382033709 0.10919382051003906 3.9616231010301473 1.0635996566275094 0.04366017064184421 3.4048997961824696 4.534892401813794e-05 4.343433012871338 0.8831200765555376 MLLS(ph)PGGVSQPLTASLAR ddPTM_PC-9_AZD4547_30min_R2 2 MLLSPGGVSQPLTASLAR 18 0 Q6PK04;I3L0U5 Q6PK04 CCDC137 Coiled-coil domain-containing protein 137 1 MLLS(1)PGGVSQPLTASLAR;MLLS(1)PGGVSQPLTASLAR 94.845 0.00082146 11143500.0 24818.0 29019.0 38647.0 52815.0 39832.0 36592.0 27721.0 43903.0 34499.0 39332.0 True False 32709.607753531523 38398.82425252578 38134.51552849881 40639.31773361585 34302.0143503677 34303.89645542767 30188.115297307228 37118.80014057564 36322.54670889558 37954.99865172908 0.8617997343030178 1.011693469017591 1.0047297294993198 1.0707237301341461 0.9037548562475061 0.9038044440521912 0.795365995775947 0.9779686855260802 0.9569898036932446 1.0 15.212002279818982 -6.316838613947145 24.999879079017866 0.9145394862001015 0.990233346041829 0.1557344190183827 0.07155924163947879 492.8938405502623 222425.73405146203 0.02263604605413201 0.02566687301705293 4.821269251743622e-07 6.316838613947145 0.0756938598417275 MLLS(ph)PGGVSQPLTASLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MLLSPGGVSQPLTASLAR 18 0 Q6PK04;I3L0U5 Q6PK04 CCDC137 Coiled-coil domain-containing protein 137 1 MLLS(0.999)PGGVSQPLTASLAR;MLLS(1)PGGVSQPLTASLAR 112.91 0.00014739 11221700.0 60600.0 50175.0 62611.0 63146.0 81634.0 62434.0 70958.0 67262.0 58293.0 43295.0 True False 70858.38309544211 55156.04240497708 64103.88369353978 59608.13434209417 65638.40371457231 59159.85113122455 64236.344548567875 65496.44376998001 59145.42484547876 51144.04077696856 1.3854670459935854 1.0784451436972735 1.2533988851816995 1.1654952060208978 1.2834027721980645 1.1567300946988472 1.2559888419589855 1.2806270833311766 1.1564480230141185 1.0 15.642278528760134 -8.5848042842126 5.717209890844378 1.000011036470611 1.2254981987439937 0.4394074160439615 0.07978446739921459 0.4410017707802282 39.01806102827765 0.07058366336625481 0.01830804440069986 2.6013315950041106e-09 8.5848042842126 0.22548716227338272 MLLS(ph)PGGVSQPLTASLAR ddPTM_PC-9_Lapatinib_30min_R1 2 MLLSPGGVSQPLTASLAR 18 0 Q6PK04;I3L0U5 Q6PK04 CCDC137 Coiled-coil domain-containing protein 137 1 MLLS(1)PGGVSQPLTASLAR;MLLS(1)PGGVSQPLTASLAR 106.19 0.0033286 0.0 27536.7 23447.9 28144.6 22721.8 23805.5 23662.3 20479.2 20185.0 23519.8 20130.2 True False 27144.02160838768 23393.607828184682 25830.65962929778 24392.836969702817 22405.307293413734 22650.31858851538 21539.51277050483 21122.868788965345 20870.752449526106 23609.67824819455 1.1496989210542674 0.990848226827217 1.094070802564752 1.0331710882831773 0.9489882521006862 0.9593658308430132 0.912317082175907 0.8946699131988649 0.8839913966689533 1.0 14.527090760256323 -6.282722527414638 1.2957909467169297 0.9169777137754456 1.076669052550934 0.6576560069619208 0.04795390864690544 0.2605085977672798 0.8901319723005817 0.018368910062229574 0.025684835450447484 5.215278110133704e-07 6.282722527414638 0.15969133877548836 MLMS(ph)SVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MLMSSVK 7 0 A6QRH7;Q5HY75;D3DWX8;P98173-3;P98173-2;P98173 A6QRH7 FAM3A Protein FAM3A 1 MLMS(1)SVK 64.77600000000001 0.034983999999999994 11569000.0 42272.0 26753.0 22455.0 30841.0 37297.0 38432.0 35327.0 28833.0 37842.0 37758.0 True False 49427.814689942774 29408.861035582493 22990.412361061735 29113.07875787106 29988.920588754725 36416.55826433068 31980.570814668616 28076.16430108876 38395.36765996958 44603.22650783645 1.1081667977821892 0.6593438039827809 0.5154428089865314 0.6527123940855738 0.6723486827457628 0.8164556942519071 0.7170012870941045 0.6294648728193686 0.8608204084344393 1.0 15.444860455132005 -8.51397912201296 4.508358359548328 0.9995873405547056 0.7122443481759577 0.26226930107266544 0.14879103115697823 0.21566170592065573 13.884729283564562 0.14417198611295412 0.03762032225142979 3.0621106360434117e-09 8.51397912201296 -0.28734299237874783 MLMS(ph)SVK ddPTM_PC-9_Lapatinib_30min_R1 1 MLMSSVK 7 0 A6QRH7;Q5HY75;D3DWX8;P98173-3;P98173-2;P98173 A6QRH7 FAM3A Protein FAM3A 1 MLMS(0.998)S(0.002)VK 69.383 0.02791 14738000.0 39455.0 40550.0 32773.0 30175.0 36268.0 40418.0 34655.0 33489.0 36419.0 27088.0 True False 38892.36446483913 40456.10896638459 30078.530447438447 32394.17016084914 34134.78754563146 38689.416358959825 36449.26633178269 35045.02119760517 32317.10871092828 31770.124707508818 1.2241804154972984 1.2734010123927166 0.9467551898003547 1.0196425245127485 1.0744303920709433 1.217792398209115 1.1472811853070242 1.1030810083449984 1.0172169296927622 1.0 14.955383132633635 -5.2368060055666374 24.987049312253617 1.0764580797090388 1.2487907616200749 0.4832883208646913 0.07504781110358011 748.2327611687693 758973.0343019105 0.02078345595037235 0.05492938438835498 5.79687578487999e-06 5.2368060055666374 0.172332681911036 MLPDKDCR ddPTM_PC-9_AZD4547_30min_R2 2 MLPDKDCR 8 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 0 ; 102.77 0.0054135 155692000.0 387450.0 404470.0 497560.0 687900.0 550320.0 519230.0 452210.0 506070.0 425490.0 438370.0 False True 510651.04053935857 535207.017658056 490962.02930007095 529315.282949055 473917.5672146599 486762.46601857577 492455.8139531508 427868.50983169884 447980.5327449486 423022.7997294428 1.2071477964449224 1.265196622972483 1.1606041792879267 1.251268922827788 1.1203121144244905 1.1506766687987022 1.1641353947544104 1.0114549620147075 1.0589985528710704 1.0 18.690375897049563 -7.421131256552532 0.5599476867496487 0.9937820260216677 1.2312148429334615 0.7643955213283152 0.0425228871053894 0.381935413812554 0.25001399702591154 0.038854008110178556 0.028063122921396844 3.792003621625497e-08 7.421131256552532 0.23743281691179385 MLPDKDCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MLPDKDCR 8 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 0 ; 98.29899999999999 0.007192699999999999 26859000.0 174989.0 176004.0 174203.0 191586.0 221222.0 202566.0 214116.0 196383.0 182153.0 153856.0 False True 204611.18150970823 193476.51395008602 178356.66018855665 180852.05755019226 177875.1371554142 191943.0823629374 193833.38241440206 191228.15433498815 184816.64302537992 181748.87487657423 1.1257906363858363 1.0645266116859102 0.9813357046071332 0.9950656237790138 0.9786863180099977 1.0560895218376787 1.0664901367121773 1.0521559182407665 1.0168791589542934 1.0 17.471586907549984 -4.920849912653597 3.545355571985691 1.0209543653414865 1.1253912985534253 0.555491321208401 0.029837139223276403 0.21248130494138112 4.878785210307347 0.008609884748670716 0.04806573441312546 1.1999139084152417e-05 4.920849912653597 0.10443693321193881 MLPDKDCR ddPTM_PC-9_Lapatinib_30min_R1 2 MLPDKDCR 8 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 0 ; 97.473 0.0075214 204390000.0 484960.0 495290.0 553710.0 454780.0 491960.0 450360.0 465210.0 456970.0 478770.0 381230.0 False True 478044.38146922813 494143.1864355274 508186.1011824099 488226.03830160643 463023.880030574 431099.1526404361 489296.29750998825 478202.49445100274 424845.88092839264 447125.0975429565 1.0691513048499837 1.1051564520778299 1.1365635791303064 1.0919226878216142 1.035557794843064 0.9641578050738233 1.0943163338376019 1.0695049262025837 0.9501722968873976 1.0 18.770319002389712 -6.258293020981314 3.9879947248170984 1.022672438436017 1.1048389813828072 0.4605686329860412 0.043463613730132786 0.21644503891468314 8.147165383720106 0.013859422548821061 0.017088280400274384 5.517050750938675e-07 6.258293020981314 0.08216654294679016 MLPHAPGVQMQAIPEDAIPEES(ph)GDEDEDDPDKR ddPTM_PC-9_Lapatinib_30min_R1 4 MLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKR 33 1 Q13547 Q13547 HDAC1 Histone deacetylase 1 1 MLPHAPGVQMQAIPEDAIPEES(1)GDEDEDDPDKR;MLPHAPGVQMQAIPEDAIPEES(1)GDEDEDDPDKR;MLPHAPGVQMQAIPEDAIPEES(1)GDEDEDDPDKR;MLPHAPGVQMQAIPEDAIPEES(1)GDEDEDDPDKR 52.192 0.0014543 38205400.0 112740.0 93687.2 95244.0 93487.0 99619.0 98822.0 80149.8 93854.0 105303.0 89623.0 True False 111132.30692601626 93470.27304452453 87413.40597247203 100362.34584348962 93759.60627848952 94595.61342533334 84299.56446801663 98214.79947087195 93442.66725025066 105114.21613485894 1.057252872279771 0.8892258010524902 0.831604032135128 0.9547932671136243 0.8919783615015333 0.8999316829225983 0.8019806222962493 0.9343626683650933 0.888963174404174 1.0 16.681598273711174 -4.760524073157736 24.993827798872807 0.8935365360294508 1.0572530647004428 0.43304648913254706 0.053902295931891386 20.0150044665667 546244.7026361321 0.012693003692067864 0.07493618488590313 1.7357050492163226e-05 4.760524073157736 0.16371652867099196 MLPHAPGVQMQAIPEDAVHEDS(ph)GDEDGEDPDKR ddPTM_PC-9_Lapatinib_30min_R1 5 MLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKR 33 1 Q92769-3;Q92769 Q92769-3 HDAC2 Histone deacetylase 2 1 MLPHAPGVQMQAIPEDAVHEDS(1)GDEDGEDPDKR;MLPHAPGVQMQAIPEDAVHEDS(1)GDEDGEDPDKR;MLPHAPGVQMQAIPEDAVHEDS(1)GDEDGEDPDKR;MLPHAPGVQMQAIPEDAVHEDS(1)GDEDGEDPDKR;MLPHAPGVQMQAIPEDAVHEDS(1)GDEDGEDPDKR 63.931999999999995 2.1701999999999997e-05 96223000.0 176450.0 143526.0 142125.0 141177.0 136911.0 149093.0 127533.0 132758.0 146569.0 113942.5 True False 173933.79064303276 143193.6743652113 130440.03111836557 151559.62753266597 128858.1641573826 142716.63994275796 134136.03471623847 138926.42133690635 130060.85578000627 133637.30930616212 1.3015361619153203 1.071509708693368 0.9760749583750478 1.1341116363353585 0.964237942430953 1.0679400886154866 1.003731932442113 1.039578109273563 0.9732376119758426 1.0 17.027963314858255 -4.773133471478581 3.5411392295581443 1.024267825269092 1.337062408775993 0.7477516949656113 0.048820899883945106 0.13352749517624918 2.7650385710976195 0.011385027413370247 0.11379628405160327 1.686034777637585e-05 4.773133471478581 0.31279458350690104 MLPPES(ph)PGLNNSISCPHWFDINDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MLPPESPGLNNSISCPHWFDINDSK 25 0 Q9NVE5;Q9NVE5-3 Q9NVE5 USP40 Ubiquitin carboxyl-terminal hydrolase 40 1 MLPPES(0.82)PGLNNS(0.154)IS(0.026)CPHWFDINDSK 64.954 0.00061831 4719500.0 25654.0 17867.0 29447.0 45740.0 46770.0 51661.0 45271.0 54206.0 43433.0 36125.0 True False 29996.71551040385 19640.717681110626 30149.12815836939 43177.336091080804 37605.75424125422 48951.80621600713 40982.6031463431 52783.14993600447 44068.12545783675 42674.17653465732 0.702924296290577 0.4602483111808766 0.7064958390909812 1.0117907267880106 0.8812297575493496 1.1471060531478916 0.9603607257203796 1.2368873689486959 1.0326649284502853 1.0 15.381075694001563 -5.705456379901345 2.5420888611113184 1.051328312567871 0.5748555913774424 0.7638059795564252 0.10717988433555951 0.12249636808731003 1.6061594218272008 0.03065109532149089 0.05853871262976872 1.970351097350682e-06 5.705456379901345 -0.4764727211904286 MLPSVS(ph)T(ph)TAIQVS(ph)CAGCKK ddPTM_PC-9_Lapatinib_30min_R1 1 MLPSVSTTAIQVSCAGCKK 19 1 Q5SVZ7;Q5SVZ6 Q5SVZ7 ZMYM1 Zinc finger MYM-type protein 1 3 MLPS(0.578)VS(0.627)T(0.605)T(0.191)AIQVS(1)CAGCKK 54.582 0.033839 5001900.0 3996.8 7304.2 16944.0 10905.0 13269.0 15499.0 6843.6 6914.9 15063.0 9621.2 True False 3939.8048990766483 7287.2875736687065 15550.929725731456 11706.99007801358 12488.543507857727 14836.143899933653 7197.928122008028 7236.191498083549 13366.446319578044 11284.211600556846 0.3491431247959077 0.645795012680292 1.3781139769626491 1.0374663727004083 1.1067271644606036 1.3147700898485037 0.6378760321769249 0.6412669093981243 1.1845263801077999 1.0 13.462018004131455 -5.0295009161516235 5.849403645154061 1.02365649636873 0.4111051961779514 0.48140457068269404 0.23314918917937366 0.13948974822231927 15.532541080057523 0.06319381319934746 0.1933578940604593 9.343273972756405e-06 5.0295009161516235 -0.6125513001907786 MLQHIDYR ddPTM_PC-9_AZD4547_30min_R2 6 MLQHIDYR 8 0 P63162-2;J3KRY3;S4R3P3;J3QLE5;P14678-2;P63162;P14678;P14678-3 P63162-2 SNRPN;SNRPB Small nuclear ribonucleoprotein-associated protein N;Small nuclear ribonucleoprotein-associated proteins B and B 0 ;;;;; 124.08 0.00027123 21372900.0 151028.0 135520.5 187499.0 260647.0 225030.0 193941.0 179494.0 221501.0 174163.0 210730.0 False True 199051.76242244977 179324.85137718104 185012.64075032977 200558.86110600713 193788.46880054323 181813.83861122944 195468.61827404704 187273.11003661843 183368.90061918856 203352.40684122036 0.9788512735817847 0.8818427780754015 0.9098128889853245 0.9862625391132229 0.952968650879334 0.8940825507572749 0.9612309060431772 0.920928908320437 0.9017296793657568 1.0 17.633622540807764 -12.119663443215728 2.2165938954025712 2.441231870078316 0.9314782288677249 0.25885676852734674 0.03452586449045232 5142479.617295455 482359.4424814034 38558221.706328586 0.009191102099198155 7.591656630423602e-13 12.119663443215728 -1.5097536412105912 MLQHIDYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 MLQHIDYR 8 0 P63162-2;J3KRY3;S4R3P3;J3QLE5;P14678-2;P63162;P14678;P14678-3 P63162-2 SNRPN;SNRPB Small nuclear ribonucleoprotein-associated protein N;Small nuclear ribonucleoprotein-associated proteins B and B 0 ;;; 76.827 0.016561000000000003 11245000.0 92075.0 97036.0 99539.0 104916.0 113855.0 103316.0 100326.0 113688.0 100571.0 75421.0 False True 107661.4789358553 106669.0927914172 101912.38726375948 99037.8966622613 91545.93006495608 97897.92708257676 90822.39498266047 110703.81046239316 102041.66061336063 89094.2302676927 1.2084001243669247 1.1972615114460166 1.1438719090737224 1.11160842138365 1.027518053524869 1.0988133214511473 1.0193970441158233 1.2425474705799946 1.1453228823770747 1.0 16.44304438555354 -5.46193219919379 2.126531427165965 1.0965957781483835 1.206812827550782 0.30987499886118 0.06625272670020928 0.44877140235717217 3.9156764947861142 0.019846448546426063 0.053976567241586774 3.451976263906214e-06 5.46193219919379 0.1102170494023984 MLQHIDYR ddPTM_PC-9_Lapatinib_30min_R1 5 MLQHIDYR 8 0 P63162-2;J3KRY3;S4R3P3;J3QLE5;P14678-2;P63162;P14678;P14678-3 P63162-2 SNRPN;SNRPB Small nuclear ribonucleoprotein-associated protein N;Small nuclear ribonucleoprotein-associated proteins B and B 0 ;;;; 141.52 0.0018708 22938200.0 156947.0 147555.0 158535.0 133397.0 138916.0 156902.0 141615.0 126162.0 164648.0 124565.0 False True 154708.90699944488 147213.34546325216 145500.8642627969 143207.46037934703 130745.23399936408 150191.66721642631 148947.13177248323 132023.94709702485 146103.6084196964 146095.89427757042 1.0589545158983757 1.007648751467024 0.9959271270577734 0.9802291918434367 0.8949275039239547 1.0280348257499574 1.0195162054964781 0.9036800640419778 1.0000528019090758 1.0 17.156556109192742 -4.747125612801162 1.2680724599817796 0.9729535061272622 1.1005162845294962 0.2630861299916072 0.042223806880595606 2.099281170758483 2.770573691788961 0.01277973962050303 0.35907458990588326 1.790088024539642e-05 4.747125612801162 0.12756277840223407 MLS(ph)SEDS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MLSSEDSPR 9 0 Q5T6X5-2;Q5T6X5-3;Q5T6X5 Q5T6X5-2 GPRC6A G-protein coupled receptor family C group 6 member A 2 MLS(0.5)S(0.5)EDS(1)PR 84.615 0.029153 735940.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MLSS(ph)TPPTPIACAPSAVNQAAPHQQNR ddPTM_PC-9_AZD4547_30min_R2 1 MLSSTPPTPIACAPSAVNQAAPHQQNR 27 0 O75376-2;O75376;A0A088AWL3;E7EVK1 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 MLS(0.096)S(0.339)T(0.339)PPT(0.227)PIACAPSAVNQAAPHQQNR 93.384 3.5554e-08 7983700.0 15679.0 14512.0 21988.0 36846.0 33107.0 24359.0 19140.0 25775.0 22922.0 25206.0 True False 20664.59585654044 19202.720202372737 21696.424753296025 28351.723965025263 28510.66451841794 22835.827879256747 20843.422920906916 21792.066000577106 24133.61012380952 24323.545612109298 0.8495716942785152 0.7894704377643367 0.8919926847545869 1.1656081895770396 1.1721426215191306 0.9388363129053068 0.8569237089567309 0.895924728577732 0.9921912910507086 1.0 14.57006592346944 -5.531063612016282 24.942736887486706 0.9994734279727996 0.8248236560057773 0.37619542195430333 0.09697971278073268 207.83823838971637 633368.7640601265 0.030416792692143327 0.05280035476205493 2.9439903898197812e-06 5.531063612016282 -0.17464977196702225 MLSS(ph)TPPTPIACAPSAVNQAAPHQQNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MLSSTPPTPIACAPSAVNQAAPHQQNR 27 0 O75376-2;O75376;A0A088AWL3;E7EVK1 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 MLS(0.023)S(0.512)T(0.374)PPT(0.092)PIACAPSAVNQAAPHQQNR 147.03 9.5847e-10 8485500.0 8434.8 15185.0 12342.0 12567.0 18715.0 15703.0 16337.0 12691.0 11196.0 13149.0 True False 9862.645045106197 16692.466445831134 12636.280087295647 11862.91173276372 15047.93009675161 14879.507036448387 14789.44109036266 12357.874697226001 11359.720319248969 15532.809612573263 0.6349556384907167 1.0746585364903443 0.8135218548656531 0.7637325138628565 0.9687835280341581 0.9579404761649786 0.9521420437929741 0.7955981567702173 0.731337124614833 1.0 13.923031191084608 -4.728457810075206 24.786095646457902 0.888276899073686 0.6349535997011734 0.3411515085578902 0.10814450249793685 5612.040696864026 4217251.820144435 0.027287055552156728 4.711547421612351 1.868711206055148e-05 4.728457810075206 -0.25332329937251263 MLSSTPPT(ph)PIACAPSAVNQAAPHQQNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MLSSTPPTPIACAPSAVNQAAPHQQNR 27 0 O75376-2;O75376;A0A088AWL3;E7EVK1 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 MLS(0.028)S(0.102)T(0.377)PPT(0.492)PIACAPSAVNQAAPHQQNR 114.66 8.0463e-12 9875800.0 17509.0 20892.0 24729.0 26058.0 23531.0 19247.0 20285.0 24973.0 20799.0 18776.0 True False 20472.927881486736 22966.019689582074 25318.633145254746 24598.054741175863 18920.269468696883 18237.65343759296 18363.45794931789 24317.485211080686 21103.14602715785 22179.940169265792 0.9230380120617087 1.0354410117573505 1.1415104347458143 1.1090225921916956 0.8530351896491697 0.8222589104574969 0.8279309055469721 1.0963728948546416 0.9514518914888676 1.0 14.436967853361969 -4.4755420012550795 10.004040675240471 0.9800091398286765 0.7536438791298652 0.024146340257141574 0.11166510528196079 17809.859029927873 178276.62744021896 0.03118586104738476 66214.99629380429 3.3454766169463595e-05 4.4755420012550795 -0.22636526069881135 MLWGSDPYPHAEPQQAT(ph)TPK ddPTM_PC-9_AZD4547_30min_R2 1 MLWGSDPYPHAEPQQATTPK 20 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3 E7EPN9 PRRC2C Protein PRRC2C 1 MLWGSDPY(0.016)PHAEPQQAT(0.971)T(0.012)PK 55.437 0.022573 9393000.0 39896.0 40753.0 51451.0 69191.0 61695.0 60420.0 50931.0 53425.0 55106.0 57096.0 True False 52582.09811164851 53925.610281649395 50768.72612251382 53240.08394029373 53129.71418321787 56641.92784862652 55463.760333579376 45169.3938343679 58018.79065887133 55097.086418669875 0.9543535153944338 0.9787379657770158 0.9214412126393425 0.966295813461619 0.9642926266463093 1.028038532168793 1.0066550509063807 0.8198145631719296 1.0530282893363927 1.0 15.749688409408057 -1.559461655304275 15.097023429536367 0.965645790926409 0.9647366300565626 0.0 0.0615731208524281 0.0 0.0 0.013486485967557214 0.0 0.027576449193758845 1.559461655304275 -0.0009091608698463816 MLWGSDPYPHAEPQQAT(ph)TPK ddPTM_PC-9_Lapatinib_30min_R1 1 MLWGSDPYPHAEPQQATTPK 20 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3 E7EPN9 PRRC2C Protein PRRC2C 1 MLWGSDPYPHAEPQQAT(0.577)T(0.423)PK 85.24799999999999 0.0028751 0.0 11383.0 7855.5 11801.0 7702.6 14702.0 11054.0 13834.0 10880.0 13732.0 9827.8 True False 11220.67633261346 7837.311072390481 10830.767333177342 8269.07489912035 13837.257265244123 10581.246188132563 14550.256829718133 11385.524519392766 12185.357555629396 11526.522135279642 0.973465907662636 0.679937190108935 0.9396387918283887 0.7173954816614541 1.200471148438776 0.9179912261432407 1.2623284507634474 0.9877675491156765 1.0571582141271592 1.0 13.492669657927985 -6.258545496779518 24.998769644261234 1.0722618498876242 0.825063434745332 0.475447965141924 0.12520239588325574 212.43500033694792 1835114.1235559913 0.03475006229470291 0.042909470818390194 5.513844362087123e-07 6.258545496779518 -0.24719841514229224 MLWGSDPYPHAEPQQATT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 MLWGSDPYPHAEPQQATTPK 20 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3 E7EPN9 PRRC2C Protein PRRC2C 1 MLWGSDPYPHAEPQQAT(0.237)T(0.763)PK;MLWGSDPYPHAEPQQAT(0.181)T(0.819)PK;MLWGSDPYPHAEPQQAT(0.277)T(0.722)PK 119.94 1.2350999999999999e-05 31621800.0 62235.6 53113.3 55047.0 71661.0 79857.0 74280.0 66490.0 63057.0 61036.0 75388.0 True False 82025.22621910246 70281.13553780892 54317.040812929146 55140.66360141328 68770.23398215773 69635.25985759652 72407.48119180262 53312.989555708686 64262.2383525364 72748.6890663214 1.1275148359625298 0.9660811272315446 0.7466394447796987 0.7579609242325213 0.9453123467209601 0.9572029510265605 0.9953097728784128 0.7328378042263533 0.883345654434428 1.0 16.150633630394324 -4.886634529193603 3.6943317814356265 0.8720773179315039 1.1301575742831376 0.38280471292143003 0.09660070256831481 0.25584417493486294 5.970200791225005 0.025596619268079438 0.149545402927271 1.2982713426222873e-05 4.886634529193603 0.2580802563516337 MLWGSDPYPHAEPQQATT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 MLWGSDPYPHAEPQQATTPK 20 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3 E7EPN9 PRRC2C Protein PRRC2C 1 MLWGSDPYPHAEPQQAT(0.299)T(0.701)PK;MLWGSDPYPHAEPQQAT(0.097)T(0.903)PK;MLWGSDPYPHAEPQQAT(0.254)T(0.745)PK 63.883 0.007404699999999999 34366900.0 97099.0 94136.0 81547.0 128533.0 140556.0 137513.0 146840.0 142688.0 123619.0 121067.0 True False 113535.9429073323 103481.1999568497 83491.38974871962 121331.71271960862 113015.06078968868 130301.57620219873 132930.2521704631 138942.59119043298 125426.6940108288 143015.48873415508 0.7938716562258445 0.7235663834230301 0.583792640137866 0.8483816249101982 0.7902295184248692 0.9111011496412835 0.9294815082411181 0.9715212836052114 0.8770147563805394 1.0 17.125811875355787 -6.5192715093188705 1.263420315368813 0.9452019121886724 0.7117848285684591 0.6785586053600077 0.06735130943362677 0.2591289124690332 0.8614864867433645 0.02963334317317091 0.03344094131389085 3.025021674012347e-07 6.5192715093188705 -0.2334170836202133 MLWGSDPYPHAEPQQATT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 MLWGSDPYPHAEPQQATTPK 20 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3 E7EPN9 PRRC2C Protein PRRC2C 1 MLWGSDPY(0.001)PHAEPQQAT(0.186)T(0.813)PK 63.165 0.008694 9702700.0 22575.0 15537.0 18028.0 19532.0 24328.0 23494.0 24742.0 22392.0 25302.0 19980.0 True False 22253.076360252027 15501.025031090438 16545.80743009245 20968.44843684195 22897.074870688273 22489.216387188924 26023.019696464227 23432.414066014957 22452.22231812812 23433.51637832347 0.9496259972675984 0.6614894999467188 0.7060744603143595 0.8948058882122462 0.9771079380928328 0.9597030178531787 1.1105042570792365 0.9999529600128843 0.9581243359147298 1.0 14.516285837417774 -6.0481526621539174 2.690615621722762 1.0055413315005681 0.7624225745169285 0.6102496956904181 0.08126683639575877 0.17609294662228495 2.5324810139048313 0.025261192008711388 0.03665337733909159 8.950500843874192e-07 6.0481526621539174 -0.2431187569836396 MMEGQRGAPRRS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 MMEGQRGAPRRSR 13 3 A0A3B3IS60 A0A3B3IS60 1 MMEGQRGAPRRS(1)R 62.298 0.0273 10946000.0 1324.0 1276.0 46122.0 102700.0 54648.0 15011.0 8394.4 61628.0 8276.1 13153.0 True False 1745.0044590891982 1688.442046460006 45510.392144420555 79024.10169918287 47061.06849314354 14072.359797016417 9141.485337892422 52104.808670555445 8713.557750006981 12692.517473461623 0.1374829274600387 0.1330265686055044 3.5856079961738696 6.226038440712161 3.7077804770836056 1.1087130529022207 0.7202263346893995 4.105159498854322 0.6865113850129322 1.0 13.631690625739425 -6.7703820359091225 24.984456999937354 1.66795107377788 2.850804613030757 0.09233156740494375 1.8967150446996206 597.1954270708294 1668465.5131209914 0.7416344325796866 0.6635007236143386 1.6967504150209708e-07 6.7703820359091225 1.182853539252877 MMEGQRGAPRRS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MMEGQRGAPRRSR 13 3 A0A3B3IS60 A0A3B3IS60 1 MMEGQRGAPRRS(1)R 64.53399999999999 0.02284 4525600.0 5873.6 5029.5 103400.0 12509.0 29192.0 22538.0 6053.3 13210.0 18834.0 6259.6 True False 6867.884471112031 5528.795521192466 105865.44814668382 11808.161284725178 23472.037156525417 21356.067604118565 5479.887601903179 12863.251497151958 19109.411619572616 7394.415929033661 0.9287933674579705 0.7476987464938285 14.316945268254452 1.5969025002179351 3.174292247257027 2.8881344800020576 0.7410845771316136 1.7395899311864909 2.584303047457858 1.0 12.852220480726807 MMMGS(ph)CPWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MMMGSCPWR 9 0 Q7Z6G3-2 Q7Z6G3-2 1 MMMGS(1)CPWR 67.89699999999999 0.039199 1727500.0 2487.0 1273.5 2990.3 3536.4 3134.0 3903.7 2644.1 2467.9 4435.0 996.48 True False 2907.999979510967 1399.9246637317049 3061.600092775902 3338.2669731634905 2519.915197607242 3698.983099928902 2393.6317063737465 2403.1202399561935 4499.853484804316 1177.1339358686603 2.4704070547121066 1.1892654022404319 2.600893576750558 2.835927902036086 2.140720882154912 3.1423638272727694 2.0334404042199137 2.041501112770844 3.8227200386366156 1.0 10.20106276614311 -5.300520950372006 24.77642302310992 2.5016664325356333 1.8298352871536228 0.09212779134078342 0.7690374794798579 883.4146535099117 560054.1018477232 0.18736253835885502 0.390037318598383 5.005864036510975e-06 5.300520950372006 -0.6718311453820105 MMNGGHYTYSENR ddPTM_PC-9_AZD4547_30min_R2 2 MMNGGHYTYSENR 13 0 Q99497;K7ELW0 Q99497 PARK7 Protein deglycase DJ-1 0 ; 78.486 0.008595499999999999 6445900.0 3888.5099999999998 2652.3999999999996 11931.0 11760.8 12666.4 12959.8 9541.5 17637.3 11425.0 10680.2 False True 5124.9752939674745 3509.7364294910017 11772.78714442308 9049.529262548696 10907.888997978944 12149.421657276222 10390.675015665272 14911.860549834279 12028.902175400217 10306.289448799876 0.4972667728213529 0.34054316511552035 1.1422915301291068 0.8780589083496462 1.0583720797060596 1.178835672880405 1.0081877738137097 1.446869954886693 1.167141892837187 1.0 13.331237395344784 -5.263975711709333 24.999924570522545 1.114628509853082 0.41890492765019366 0.7812441246817545 0.14625672925168176 91.87444105339321 905590.6979044263 0.03994531464683189 0.08983699340128062 5.44533105470926e-06 5.263975711709333 -0.6957235822028882 MMNGGHYTYSENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 MMNGGHYTYSENR 13 0 Q99497;K7ELW0 Q99497 PARK7 Protein deglycase DJ-1 0 ;; 82.20200000000001 0.0061994 5935500.0 12249.6 16121.5 25586.399999999998 21368.2 30142.2 26725.9 25341.0 16544.9 18635.1 13391.3 False True 14323.215339371754 17721.935976718232 26196.47681296236 20171.009030639118 24236.05228759317 25324.346755741968 22940.517027047805 16110.613905770577 18907.60308335445 15819.036684527528 0.9054416918687075 1.1202917301564839 1.6560096126829849 1.2751098207116631 1.5320814263802964 1.6008779333896803 1.4501841979724177 1.018432046594104 1.1952436460209883 1.0 13.949374127731216 -7.762773498867446 24.99915884551168 1.0801283339927215 1.3770907715427934 0.26954443303212783 0.21897910533292467 51.32425939780885 961655.6705750112 0.11941311585947462 0.0622955823355906 1.7267382170159388e-08 7.762773498867446 0.2969624375500719 MMNGGHYTYSENR ddPTM_PC-9_Lapatinib_30min_R1 2 MMNGGHYTYSENR 13 0 Q99497;K7ELW0 Q99497 PARK7 Protein deglycase DJ-1 0 ; 69.352 0.020424 1173300.0 3910.0 5669.6 9120.900000000001 4821.5 7796.1 8945.3 5277.4 7369.1 8301.7 5812.7 False True 3854.2426829938177 5656.472389539184 8371.01480969217 5176.089194052498 7337.548725722333 8562.730371512778 5550.637949483484 7711.495288222167 7366.675125223467 6817.417450064102 0.5653523069733066 0.8297089669176704 1.227886493823766 0.7592448653710987 1.0762944735991398 1.256007928842947 0.8141848420080675 1.1311461187035947 1.080566824487798 1.0 12.735009610773776 -4.938870654201311 3.5735046943424233 1.0388794561223322 0.5720230016433594 0.49476985710897603 0.15089164939423946 0.1974456983339115 4.811869309044666 0.03730399221776627 0.1971237299565822 1.1511431825326514e-05 4.938870654201311 -0.46685645447897284 MMS(ph)S(ph)SWPGT(ph)S(ph)PRLSR ddPTM_PC-9_Lapatinib_30min_R1 1 MMSSSWPGTSPRLSR 15 1 Q18PE1-2 Q18PE1-2 4 MMS(0.988)S(0.516)S(0.516)WPGT(0.948)S(0.701)PRLS(0.331)R 42.946999999999996 0.037307 3742300.0 4146.5 6827.0 5693.5 6458.8 5498.7 7579.1 4957.8 8194.2 7035.0 6280.1 True False 4087.3701496250287 6811.192500949627 5225.402407545565 6933.801697925184 5175.277276860146 7254.959560745026 5214.490625298294 8574.93244639781 6242.644218165807 7365.606917292755 0.5549264569127117 0.9247292962319928 0.7094327006885909 0.9413754733023031 0.7026274053139848 0.9849778357995246 0.707951250161866 1.1641854558197826 0.8475396920122782 1.0 12.84658869118505 -2.7837136262059388 0.19719884801948084 1.017635633366826 1.8077315325521354e-11 0.29259749621385767 0.14615142896527883 42.980895305120555 0.7914146466404851 0.2717544674874219 12.165392605854732 0.0016454563795491916 2.7837136262059388 -1.0176356333487486 MNDLT(ph)IIQT(ph)T(ph)QGFCRY(ph)LEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MNDLTIIQTTQGFCRYLEK 19 1 Q96G03;E7ENQ8 Q96G03 PGM2 Phosphoglucomutase-2 4 MNDLT(1)IIQT(1)T(1)QGFCRY(1)LEK 53.773 0.031393 0.0 9935.6 11367.0 12730.0 12612.0 15933.0 9964.4 12867.0 11697.0 9513.8 9020.1 True False 11617.500842955025 12495.440638114093 13033.531478793848 11905.390528655691 12811.043025997511 9441.849322676328 11648.144610987096 11389.96614399594 9652.921326658703 10655.372726927691 1.0902951159649155 1.1726892111935492 1.2231886967084877 1.1173133811235922 1.2023082959474636 0.8861115950280545 1.0931710142387159 1.068941128188958 0.9059205692790411 1.0 13.379293439294665 -6.743683529940022 24.999999950234123 1.0015340440153722 1.1628097685819874 0.5996168885534376 0.06931044800562257 178.3745108840198 251148.47791886053 0.022581832654548963 0.02253592907204587 1.804332077341357e-07 6.743683529940022 0.1612757245666152 MNEGDAYYLLKDFALT(ph)IK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MNEGDAYYLLKDFALTIK 18 1 H0Y8Z7;Q8IY21 H0Y8Z7 DDX60 Probable ATP-dependent RNA helicase DDX60 1 MNEGDAYYLLKDFALT(1)IK 62.361999999999995 0.013556 5811500.0 2191.1 795.77 19740.0 6731.8 20502.0 22534.0 7259.8 11689.0 20238.0 6401.9 True False 2562.0099538023646 874.7687865392847 20210.676464366876 6354.639070790066 16484.780274838453 21352.27737116015 6572.099187599606 11382.176135519245 20533.94246346556 7562.513792587481 0.33877755784241476 0.11567169469452121 2.6724812699418408 0.8402813198196964 2.179801680625862 2.8234364864350963 0.869036324144143 1.505078396904964 2.7152271092176035 1.0 12.884650153140571 -5.24390779823301 24.812935689855852 1.822630782871084 0.22722422048666127 0.4342923716579752 0.7297232142376813 676.9850039069776 958151.7620281321 0.18052313344263346 0.4752004833850512 5.702853323824759e-06 5.24390779823301 -1.5954065623844227 MNEVS(ph)VIK ddPTM_PC-9_AZD4547_30min_R2 1 MNEVSVIK 8 0 P31751;P31751-2;A0A1B0GXA2;C9JHS6;J3QLS6;M0QZK3;E7EVP8;A8MX96;C9JIF6;C9J258;A0A5F9ZHJ8;A0A0A0MRF1;C9JIJ1;C9JC83;J3KSY8;J3KRI8 P31751 AKT2 RAC-beta serine/threonine-protein kinase 1 MNEVS(1)VIK 110.81 0.0033076 16645000.0 62276.0 56016.0 87108.0 120460.0 79830.0 71986.0 64460.0 64035.0 57318.0 66873.0 True False 82078.47257873016 74122.07654741673 85952.89100464397 92689.80808844765 68746.98246610381 67484.70404023888 70196.81512443347 54139.86212791288 60347.712462983785 64531.796624557 1.2719074451972707 1.1486132484216351 1.3319463504900368 1.436343212753128 1.0653195178505654 1.0457589524875894 1.0877864680079385 0.8389641224913679 0.9351624411464007 1.0 15.97772257154726 -6.450041834097478 4.714573765513113 0.984296690458305 1.2885718528892993 0.7298060671387021 0.09090269070386965 0.13093208410020035 5.444402272908718 0.031899938671474504 0.03571451682699612 3.54779212923143e-07 6.450041834097478 0.3042751624309943 MNGHISNHPS(ph)SFGMYPSQMKTK ddPTM_PC-9_AZD4547_30min_R2 1 MNGHISNHPSSFGMYPSQMKTK 22 1 F5H714 F5H714 EPS8 1 MNGHIS(0.004)NHPS(0.845)S(0.128)FGMY(0.02)PS(0.001)QMKT(0.001)K 46.621 0.039899000000000004 0.0 7552.9 5232.8 6278.4 7644.7 7125.2 8980.8 5731.2 9979.2 7474.3 11030.0 True False 9954.565089920547 6924.20026701875 6195.144313766312 5882.33252443762 6135.988969904594 8419.229156288398 6241.265697194442 8437.143939203073 7869.376238914128 10643.843057270704 0.9352416262019837 0.6505357350500295 0.5820401785738911 0.5526511893107496 0.5764824731902789 0.7909952364937687 0.5863733299723068 0.7926783487698782 0.7393359895079095 1.0 13.37773152274051 -8.849919325750468 0.822867612673188 1.000249891566531 0.6594237421012552 0.4090155035416262 0.1155023558634666 1.130535813433902 1.4272648570685633 0.11603636648568165 0.039840554920807215 1.4127999610150682e-09 8.849919325750468 -0.3408261494652758 MNGVMFPGNS(ph)PSYTER ddPTM_PC-9_AZD4547_30min_R2 4 MNGVMFPGNSPSYTER 16 0 Q9NY27-2;Q9NY27-3;Q9NY27 Q9NY27-2 PPP4R2 Serine/threonine-protein phosphatase 4 regulatory subunit 2 1 MNGVMFPGNS(0.933)PS(0.066)YT(0.001)ER;MNGVMFPGNS(0.974)PS(0.026)YTER;MNGVMFPGNS(0.955)PS(0.044)YT(0.001)ER;MNGVMFPGNS(0.774)PS(0.21)YT(0.016)ER 138.98 1.5109e-05 54957500.0 64913.2 64548.9 85103.0 111316.0 94636.0 83709.0 71124.7 96276.0 71927.1 76499.0 True False 85554.24732156261 85413.06960246265 83974.4786146876 85653.81601505591 81497.42493626707 78474.66299703189 77454.66051319882 81398.7564023886 75729.01966391507 73820.79329448356 1.1589451088702383 1.1570326704799223 1.1375450583374156 1.1602938981347495 1.1039900995260254 1.0630428026421128 1.0492255238198152 1.1026535041106271 1.0258494427419558 1.0 16.17173962073454 -6.807352985244873 0.33239657488742186 1.000043254687513 1.1957839285025245 0.8418450157126427 0.022165767270089724 0.8034875152534248 0.1875752454473145 0.029276766003595498 0.05760947476971788 1.5582854469726225e-07 6.807352985244873 0.19574067381501137 MNGVMFPGNS(ph)PSYTER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MNGVMFPGNSPSYTER 16 0 Q9NY27-2;Q9NY27-3;Q9NY27 Q9NY27-2 PPP4R2 Serine/threonine-protein phosphatase 4 regulatory subunit 2 1 MNGVMFPGNS(0.965)PS(0.031)YT(0.004)ER;MNGVMFPGNS(0.993)PS(0.007)YTER 125.41 1.9052e-05 58191000.0 51682.0 56760.0 57923.0 58491.0 56591.0 62024.0 59994.0 62861.0 54956.0 44584.0 True False 60430.74183397098 62394.75768622818 59304.10399420076 55213.93890038058 45502.39979189261 58771.352252988254 54310.93400105384 61210.965356734974 55759.62753346246 52666.7262732502 1.1474178501325263 1.184709248159951 1.1260260166260179 1.0483647419798736 0.8639686384874771 1.1159104886843638 1.031219098739364 1.1622322040514688 1.0587259068309163 1.0 15.684604164916903 -5.653658078780791 3.674345504740766 1.0421898831570096 1.1637643821022305 0.3359052086186167 0.07388610402673296 0.2812281325240163 7.208592093523893 0.021688387418664874 0.03959684467514747 2.2199434994858603e-06 5.653658078780791 0.12157449894522099 MNGVMFPGNS(ph)PSYTER ddPTM_PC-9_Lapatinib_30min_R1 6 MNGVMFPGNSPSYTER 16 0 Q9NY27-2;Q9NY27-3;Q9NY27 Q9NY27-2 PPP4R2 Serine/threonine-protein phosphatase 4 regulatory subunit 2 1 MNGVMFPGNS(0.86)PS(0.112)Y(0.001)T(0.027)ER;MNGVMFPGNS(0.898)PS(0.096)Y(0.004)T(0.002)ER;MNGVMFPGNS(0.968)PS(0.031)YTER;MNGVMFPGNS(0.939)PS(0.027)YT(0.034)ER;MNGVMFPGNS(0.979)PS(0.02)YT(0.001)ER;MNGVMFPGNS(0.958)PS(0.04)YT(0.002)ER 103.39 0.0012068 74440600.0 209868.0 157927.7 177373.0 158991.1 165571.0 161309.0 138046.9 150603.8 160819.4 129541.6 True False 206875.24383492192 157562.02811369888 162790.07661958024 170683.83587276196 155832.4393051104 154410.19009964503 145194.29301333058 157601.40235420247 142706.22566864153 151932.69295666792 1.3616242811803771 1.0370515064762031 1.0714617996405087 1.1234174327538706 1.025667591829987 1.0163065440015844 0.9556487822850663 1.0373106622888024 0.9392726666757771 1.0 17.213072817558533 -2.2497583989640164 1.2185276162580452 1.016789988158174 199.9986101685235 0.7920074378056614 0.05164184037011842 401.3114071788218 1.3676147073471965 0.016017176647376313 222317.71384801425 0.005626542466065069 2.2497583989640164 198.98182018036533 MNGVMFPGNSPS(ph)YTER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MNGVMFPGNSPSYTER 16 0 Q9NY27-2;Q9NY27-3;Q9NY27 Q9NY27-2 PPP4R2 Serine/threonine-protein phosphatase 4 regulatory subunit 2 1 MNGVMFPGNS(0.232)PS(0.687)Y(0.067)T(0.014)ER 84.821 0.0029163 18487000.0 28343.0 27209.0 37046.0 31263.0 37541.0 37562.0 36093.0 25342.0 27040.0 22132.0 True False 33140.91010023297 29910.129701983475 37929.317137737366 29511.435466013525 30185.110540323385 35592.182595878134 32674.009749308887 24676.799352068498 27435.408845345843 26144.356403184403 1.2676123898080116 1.1440377127945056 1.4507649969581025 1.1287879881571308 1.1545555023357474 1.3613715345290724 1.2497538377088973 0.9438671570841516 1.049381687667178 1.0 14.674211935281622 -7.753827060470142 24.85491383660741 0.9974683064362558 1.2503911769994804 0.5898964124499326 0.09675777341400793 106.69185770213497 348361.96072606987 0.04610008506365863 0.025957853732405296 1.7626778190564025e-08 7.753827060470142 0.2529228705632246 MNGVMFPGNSPS(ph)YTER ddPTM_PC-9_Lapatinib_30min_R1 2 MNGVMFPGNSPSYTER 16 0 Q9NY27-2;Q9NY27-3;Q9NY27 Q9NY27-2 PPP4R2 Serine/threonine-protein phosphatase 4 regulatory subunit 2 1 MNGVMFPGNS(0.12)PS(0.834)Y(0.006)T(0.04)ER;MNGVMFPGNS(0.177)PS(0.811)Y(0.001)T(0.012)ER 131.4 7.1122e-05 3687000.0 39385.0 36538.0 36069.0 31234.0 35539.0 34955.0 32044.0 28152.0 36613.0 26478.0 True False 38823.36267767555 36453.39850588804 33103.54605036637 33531.052553569585 33448.665892362296 33460.05613408482 33703.08152750385 29460.044693928776 32489.25838801772 31054.687020282738 1.2501611319514783 1.1738453033540235 1.0659758389690246 1.0797420863288514 1.0770891321659748 1.077455912282454 1.0852816357637534 0.948650510458777 1.04619500324695 1.0 14.922523407435136 -1.5228787452803587 0.39026420932233097 1.0184645517510602 4.555739394485086 0.7826423054063051 0.03694448276080266 33.38153688186581 0.44937645014939565 0.028756997943922762 90.07500349792444 0.029999999999998538 1.5228787452803587 3.537274842734026 MNLS(ph)LSQK ddPTM_PC-9_AZD4547_30min_R2 1 MNLSLSQK 8 0 Q86UV5-5 Q86UV5-5 1 MNLS(0.871)LS(0.129)QK 83.61399999999999 0.037361 0.0 11192.0 15064.0 19966.0 26268.0 21461.0 22653.0 14010.0 23881.0 25052.0 22220.0 True False 14750.823191938307 19933.143407424406 19701.237794447352 20212.318436554404 18481.510593825085 21236.504328946314 15256.862859033743 20190.740180786877 26376.19757532836 21442.08456324162 0.6879379263910651 0.9296271241088189 0.9188116825274246 0.9426470815810783 0.8619269520794691 0.990412301859506 0.7115382281995444 0.9416407309296814 1.2301134946807055 1.0 14.388157548538219 -8.058192998333874 7.173070407322933 1.1083992931321642 0.8724052494135303 0.4699431412799394 0.105319350602596 0.23298232569594388 24.528861318550323 0.06792306915414262 0.02568247237113677 8.74595023123073e-09 8.058192998333874 -0.23599404371863397 MNLS(ph)LSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MNLSLSQK 8 0 Q86UV5-5 Q86UV5-5 1 MNLS(0.861)LS(0.139)QK 77.732 0.023126 3802600.0 23825.0 23479.0 38349.0 33503.0 31467.0 29592.0 20880.0 32465.0 28213.0 23419.0 True False 27858.101934800477 25809.839952694685 39263.38559939241 31625.93552819151 25301.267237749536 28040.14342626127 18902.09524189093 31612.828149510864 28625.561751247846 27664.679315298003 1.0069916812444493 0.9329527972667433 1.4192604639259476 1.1431882208988056 0.9145693304226539 1.0135719668637417 0.6832573414808556 1.1427144261899909 1.0347331854094002 1.0 14.755757579928389 -6.253909074453289 23.976902293798105 0.9603041239746102 1.132813785353156 0.19183584857763591 0.16124762751271743 572.7373174322369 1823623.577345128 0.049857704246707234 0.0630156951944467 5.573024156747993e-07 6.253909074453289 0.17250966137854573 MNLT(ph)VHQRTHTGEK ddPTM_PC-9_Lapatinib_30min_R1 1 MNLTVHQRTHTGEK 14 1 M0R0C0;Q9NQZ8 M0R0C0 ZNF71 Endothelial zinc finger protein induced by tumor necrosis factor alpha 1 MNLT(0.972)VHQRT(0.025)HT(0.003)GEK 59.261 0.038974 2062300.0 8974.6 9206.3 10692.0 9049.2 15609.0 11835.0 9132.3 7163.6 10659.0 11285.0 True False 8846.620558259927 9184.98337798338 9812.945032313548 9714.708355246266 14690.909308474727 11328.84463873249 9605.12580931292 7496.447008007534 9458.471175753992 13235.597213682693 0.6683960244056437 0.6939606297846637 0.7414055349288753 0.7339833781888887 1.109954395808265 0.8559375490076835 0.7257039976543963 0.566385247826812 0.7146236790868806 1.0 13.69213567281719 -6.018767736513741 24.93594464556902 0.8140808569550833 0.7067196054809713 0.14036423218090655 0.14343952653197614 1899.9876049394272 2524438.7853928567 0.04653287624428359 0.06114194574452129 9.577061217613012e-07 6.018767736513741 -0.10736125147411191 MNMLRQKFPS(ph)VPVMALT(ph)AT(ph)ANPRVQK ddPTM_PC-9_AZD4547_30min_R2 1 MNMLRQKFPSVPVMALTATANPRVQK 26 3 H0YNU5;A0A3B3IT82;P54132 H0YNU5 BLM Bloom syndrome protein 3 MNMLRQKFPS(1)VPVMALT(1)AT(1)ANPRVQK 46.464 0.037443000000000004 0.0 3205.3 3205.9 4296.6 3624.0 4419.1 5974.0 5284.4 5583.6 4765.4 4522.8 True False 4224.518725618283 4242.144480208566 4239.624276651434 2788.5427902418587 3805.5842442184667 5600.444835612296 5754.701362760736 4720.782918363621 5017.289315243084 4364.45814863318 0.9679365872579802 0.971975062136197 0.9713976242341011 0.6389207308850352 0.871948845565231 1.283193616455273 1.3185374144469546 1.0816423843683853 1.1495789727790955 1.0 12.091586837759916 -6.75020809820275 24.8597279694399 1.1811898062145654 0.8804904808091853 0.55962567302778 0.12478667174620013 154.39661909018758 341746.4733296621 0.043758064167099736 0.04337144077599398 1.7774275269966817e-07 6.75020809820275 -0.30069932540538 MNS(ph)LTFK ddPTM_PC-9_Lapatinib_30min_R1 1 MNSLTFK 7 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 MNS(0.868)LT(0.132)FK 71.61399999999999 0.040964 8835800.0 43640.0 52714.0 54398.0 48157.0 64535.0 63307.0 67593.0 82705.0 64880.0 51691.0 True False 43017.685597404154 52591.943971738525 49925.60642235243 51698.626427042655 60739.17818069167 60599.50718582485 71092.63480491095 86547.7762294465 57572.531183311636 60625.72047607202 0.7095616391789114 0.8674856737165821 0.8235053708278361 0.852750714071056 1.0018714450521777 0.9995676209694281 1.1726480814849871 1.4275752197222216 0.949638713259244 1.0 15.887642366826555 -6.586014126254986 1.234174164030331 1.1650683303715608 0.8022325026957615 0.5451730488361757 0.12903907998248276 0.3208893469496641 1.0264939056679083 0.058470425378197334 0.06216080791113617 2.5940949828676607e-07 6.586014126254986 -0.36283582767579925 MNS(ph)LTFKK ddPTM_PC-9_AZD4547_30min_R2 1 MNSLTFKK 8 1 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 MNS(0.996)LT(0.004)FKK 78.655 0.032054 5688900.0 19081.0 16001.0 20353.0 37018.0 22013.0 23371.0 14850.0 20033.0 18675.0 20495.0 True False 25148.36109054456 21173.010333390706 20083.10592158605 28484.07202239879 18956.874922038656 21909.60767544272 16171.621231738109 16937.36016254359 19662.12237423186 19777.47628819249 1.271565730838903 1.0705617857841334 1.0154534192806 1.4402278433980118 0.9585082871951793 1.1078060393642413 0.8176787066301708 0.8563964337884455 0.9941674098211662 1.0 14.271570721783906 -6.809585732404475 1.8507499782900496 0.9135485592773739 1.1702152487357722 0.40062141366875936 0.13667690242691896 0.34381097870752847 2.427998367915595 0.05657807977171081 0.04999267027562726 1.5502947188634517e-07 6.809585732404475 0.2566666894583983 MNS(ph)LTFKK ddPTM_PC-9_Lapatinib_30min_R1 1 MNSLTFKK 8 1 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 MNS(0.999)LT(0.001)FKK 77.37899999999999 0.034706 7349800.0 28566.0 16849.0 15431.0 13841.0 18178.0 16977.0 19095.0 15874.0 17018.0 13909.0 True False 28158.64360163718 16809.987175699465 14162.322745382555 14858.913312222476 17108.805779323047 16250.933285319925 20083.64566744744 16611.563990886083 15101.25363251537 16313.15211742247 1.7261313692749611 1.0304561040503248 0.868153661747393 0.910854824700196 1.0487737536052777 0.9961859711933847 1.231132127187 1.0182927169020208 0.9257103424167307 1.0 13.993747954045267 -4.762221054578816 6.236939361231047 1.0035337828623896 1.7493081419894954 0.843896393299209 0.09333775786526594 0.0499203624908855 8.240756388091867 0.025145457154978904 0.15891890687824994 1.7289361119565047e-05 4.762221054578816 0.7457743591271058 MNS(ph)QDSNTSVLEVVSEKPLSER ddPTM_PC-9_AZD4547_30min_R2 1 MNSQDSNTSVLEVVSEKPLSER 22 1 A0A494C100;Q9UJA3-2;Q9UJA3-3;Q9UJA3;Q9UJA3-4 A0A494C100 MCM8 DNA helicase MCM8 1 MNS(0.789)QDS(0.07)NT(0.07)S(0.07)VLEVVSEKPLSER 65.184 0.0046037 4455400.0 15319.0 14717.0 20283.0 31441.0 21862.0 16462.0 20250.0 21122.0 20966.0 20761.0 True False 20190.123345005602 19473.982443379242 20014.034167323236 24192.763208607703 18826.83866558893 15432.628537638016 22052.21077055197 17858.080235274087 22074.219957062676 20034.1637091566 1.0077846841082625 0.97203869979752 0.9989952392260744 1.2075753976968062 0.9397366887335624 0.7703155850016612 1.1007302870582525 0.891381367075086 1.1018288698007228 1.0 14.29017466781409 -4.359175937233597 17.2816011460732 0.9951871587803596 9.514982886102281 7.808028031441872e-05 0.11515715715805129 2076.436595457879 219092.927945107 0.027853518006679685 358.76172435863697 4.373448962777497e-05 4.359175937233597 8.519795727321922 MNS(ph)QDSNTSVLEVVSEKPLSER ddPTM_PC-9_Lapatinib_30min_R1 1 MNSQDSNTSVLEVVSEKPLSER 22 1 A0A494C100;Q9UJA3-2;Q9UJA3-3;Q9UJA3;Q9UJA3-4 A0A494C100 MCM8 DNA helicase MCM8 1 MNS(0.611)QDS(0.171)NT(0.171)S(0.048)VLEVVSEKPLSER 82.36 0.00053988 2924800.0 28676.0 22222.0 19498.0 19178.0 31758.0 26722.0 31039.0 27637.0 29942.0 30378.0 True False 28267.074981465634 22170.5463243156 17894.949704456554 20588.41409593256 29890.056878630316 25579.162352024465 32646.047545006582 28921.115913828828 26569.61665676199 35628.79682385935 0.7933771976980196 0.6222648054583972 0.5022608479574852 0.5778588089212494 0.8389297294096104 0.7179350590614106 0.9162826268425845 0.8117342849607925 0.7457343223829903 1.0 15.12075614436896 -6.26569001447797 24.46311056701566 0.8268900119164215 0.6151293260667839 0.5154864599206596 0.10136162850776767 228.79984400196858 1316779.9142076562 0.031186759985450643 0.03663055929782818 5.423878914140132e-07 6.26569001447797 -0.2117606858496376 MNS(ph)TGGQTPR ddPTM_PC-9_AZD4547_30min_R2 9 MNSTGGQTPR 10 0 Q96ST2-3;Q96ST2;A0A1B0GW95;Q96ST2-2 Q96ST2-3 IWS1 Protein IWS1 homolog 1 MNS(0.616)T(0.384)GGQTPR;MNS(0.596)T(0.403)GGQT(0.001)PR;MNS(0.642)T(0.358)GGQT(0.001)PR;MNS(0.623)T(0.377)GGQTPR;MNS(0.634)T(0.365)GGQT(0.001)PR;MNS(0.591)T(0.409)GGQTPR;MNS(0.464)T(0.268)GGQT(0.268)PR;MNS(0.836)T(0.163)GGQTPR;MNS(0.912)T(0.088)GGQTPR 140.14 0.00012246 246156600.0 918673.4 1082066.0 1241924.0 1406174.0 1286756.0 1189381.0 1047660.1 1342420.0 1059482.6 1068749.0 True False 1210792.431606222 1431822.6735460754 1225455.276301274 1082002.3094717315 1108112.140425327 1115008.8180491128 1140899.8193134596 1134979.8347427647 1115484.687259405 1031332.42281188 1.1740079191004706 1.3883231457441019 1.1882252988421784 1.0491305087856178 1.074447109307502 1.0811342622285576 1.1062386812225384 1.1004985489046246 1.0815956742813222 1.0 19.97607799169375 -5.554459738366015 4.5831271587370885 1.077814733481881 1.284136630388239 0.6979000683853449 0.05616825155457497 0.09330062795397531 4.641582458097638 0.014272045419832116 0.02668924660527956 2.789589255563233e-06 5.554459738366015 0.20632189690635805 MNS(ph)TGGQTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 MNSTGGQTPR 10 0 Q96ST2-3;Q96ST2;A0A1B0GW95;Q96ST2-2 Q96ST2-3 IWS1 Protein IWS1 homolog 1 MNS(0.679)T(0.314)GGQT(0.007)PR;MNS(0.61)T(0.389)GGQTPR;MNS(0.927)T(0.073)GGQTPR;MNS(0.637)T(0.363)GGQTPR;MNS(0.621)T(0.379)GGQTPR 93.839 0.0057567 117525300.0 190654.0 277812.0 256077.0 418109.0 800577.0 1079906.0 1415620.0 1337330.0 1197000.0 1041514.0 True False 222927.9566118554 305391.3393644539 262182.8468574305 394683.7082576668 643709.6838400812 1023273.8282941362 1281522.225398739 1302226.5045182614 1214503.8604984803 1230332.2435797136 0.18119329780648133 0.24821859376447977 0.21309922439697773 0.3207944116861594 0.5231998813321964 0.8317052841896344 1.0416066327499356 1.0584348344227472 0.9871348709555234 1.0 20.23061652833541 -6.654711640792261 1.4249075561082756 1.0369652109496887 0.21691904819038443 0.9919203031408567 0.03222176340881329 0.032376257131785866 0.1368450223369929 0.014486120856879316 0.014366014557698292 2.214564629608643e-07 6.654711640792261 -0.8200461627593043 down MNS(ph)TGGQTPR ddPTM_PC-9_Lapatinib_30min_R1 8 MNSTGGQTPR 10 0 Q96ST2-3;Q96ST2;A0A1B0GW95;Q96ST2-2 Q96ST2-3 IWS1 Protein IWS1 homolog 1 MNS(0.644)T(0.356)GGQTPR;MNS(0.678)T(0.322)GGQTPR;MNS(0.574)T(0.426)GGQTPR;MNS(0.925)T(0.074)GGQTPR;MNS(0.627)T(0.372)GGQT(0.001)PR;MNS(0.639)T(0.36)GGQT(0.002)PR;MNS(0.974)T(0.026)GGQTPR;MNS(0.768)T(0.212)GGQT(0.02)PR 123.28 0.00046875 109564100.0 112741.6 141732.80000000002 188249.0 177727.4 553115.0 808917.0 932973.0 903497.0 881328.0 834195.0 True False 111133.88410972273 141404.62640963707 172771.89388215396 190798.06587722653 520581.86316593003 774321.5055876272 981277.776868051 945476.7689979583 782063.5598447239 978384.4942550309 0.11358917149882179 0.14452868707542885 0.17658895341928663 0.19501337868452778 0.5320831086579265 0.7914286358117492 1.0029572040746855 0.9663652424478277 0.7993417357254918 1.0 19.900042014198846 -6.553267398043574 1.6196036122067676 0.9416735907977978 0.13810428528523463 0.9741415387732949 0.058361584997314184 0.053725078336808466 0.28782333381205794 0.023638040724722618 0.025339724308978313 2.7972584983762205e-07 6.553267398043574 -0.8035693055125631 down MNSSAGY(ph)NHQQMSEGHR ddPTM_PC-9_AZD4547_30min_R2 1 MNSSAGYNHQQMSEGHR 17 0 A0A1W2PRT1 A0A1W2PRT1 1 MNS(0.323)S(0.323)AGY(0.354)NHQQMSEGHR 51.193000000000005 0.043507 0.0 0.0 0.0 0.0 467.84 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 359.98671605594666 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MNSTGGQT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 MNSTGGQTPR 10 0 Q96ST2-3;Q96ST2;A0A1B0GW95;Q96ST2-2 Q96ST2-3 IWS1 Protein IWS1 homolog 1 MNSTGGQT(1)PR 89.805 0.03482 6076500.0 2481.3 2753.5 3671.7 3736.6 4273.4 4334.0 2546.4 3134.2 2833.3 2974.5 True False 3270.3017857538 3643.51502737275 3623.01085895384 2875.1845998945196 3680.112174253397 4062.994294868376 2773.024666969557 2649.881406751069 2983.0624537034105 2870.363660367338 1.1393336081098795 1.2693565897871166 1.2622131853809009 1.001679557051863 1.2821065933444928 1.4154980955787357 0.9660882714125066 0.9231866482074774 1.0392628972043387 1.0 11.48701781521177 -7.294126791602666 24.858275964252808 0.9757332641977853 1.2239054065665211 0.5743121936129184 0.10375173533883597 470.75342702289305 357998.86209418456 0.04496771592227579 0.030319436144482792 5.0801110785090766e-08 7.294126791602666 0.24817214236873586 MNSTGGQT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 MNSTGGQTPR 10 0 Q96ST2-3;Q96ST2;A0A1B0GW95;Q96ST2-2 Q96ST2-3 IWS1 Protein IWS1 homolog 1 MNSTGGQT(0.999)PR;MNSTGGQT(1)PR;MNST(0.002)GGQT(0.998)PR 99.73200000000001 0.0081482 8441500.0 47510.0 47740.0 55948.0 38757.2 37673.0 34702.3 29237.5 26432.699999999997 36093.9 21780.0 True False 46832.49868773305 47629.460963136844 51348.17140552547 41607.53377822907 35457.14820796774 33218.16352401238 30751.274689813778 27660.859739315518 32028.62489638304 25544.64397997422 1.8333588334387239 1.8645576348793926 2.0101345489794253 1.6288163503412847 1.3880462861711618 1.3003964177404013 1.2038247514399225 1.0828438149696002 1.2538293710999437 1.0 14.640733208342262 -6.315856926684795 1.260685232687978 1.1491632108633172 1.9137353270584638 0.9267617154314857 0.09084012359440545 0.10939126111387205 0.35583154123379807 0.0370596208568272 0.05059194320846183 4.832179664146138e-07 6.315856926684795 0.7645721161951466 MNVLADALK ddPTM_PC-9_Lapatinib_30min_R1 1 MNVLADALK 9 0 I3L3P7;I3L246;H3BN98;P62244;H3BV27;H3BT37;I3L303 I3L3P7 RPS15A 40S ribosomal protein S15a 0 96.89 0.022851 2307100.0 31008.0 25126.0 27580.0 28127.0 29583.0 29167.0 28876.0 29763.0 24940.0 24464.0 False True 30565.820233829214 25067.822290736833 25312.478861878746 30195.55340892142 27842.986102415784 27919.595401597817 30371.05798864688 31145.897635173416 22130.994570157098 28692.56980376904 1.0652869520879968 0.8736694713013797 0.8821962980309178 1.0523823280881222 0.9703901146825247 0.9730601194853697 1.058499053809302 1.0855039422464734 0.7713144804216868 1.0 14.808389566098798 -5.756486925145075 24.99770591245187 0.9925376379819918 0.933712780871488 0.0455800557261723 0.09487423882668637 351.80276938678224 1775712.3662101454 0.02544311783283532 0.04235106167291266 1.7519151765134467e-06 5.756486925145075 -0.05882485711050378 MNYMQNHQAGAPAPS(ph)LSR ddPTM_PC-9_AZD4547_30min_R2 2 MNYMQNHQAGAPAPSLSR 18 0 H0YJG4;Q9HCK8-2;Q9HCK8;A0A2R8Y840 H0YJG4 CHD8 Chromodomain-helicase-DNA-binding protein 8 1 MNYMQNHQAGAPAPS(0.583)LS(0.417)R;MNYMQNHQAGAPAPS(0.586)LS(0.414)R 53.278 0.025061 28724000.0 26121.0 23295.0 30145.0 35638.0 29616.0 29602.0 24490.0 30229.0 21927.0 28015.1 True False 34426.93464944786 30824.653191446578 29745.257603606915 27422.209701611297 25504.32960937159 27750.982260427692 26669.5625565836 25557.802643315037 23086.016455142297 27034.299876132794 1.273453901421048 1.140205344051099 1.1002784514448434 1.0143488023457552 0.9434063292272667 1.026510114468606 0.9865083497179373 0.9453842992205143 0.8539528140517434 1.0 14.722503374093636 -3.375219111685919 0.45441478549192676 0.9395157455706727 2.3612453701347116 0.845040112274648 0.04401630867929021 6.184051622446522 0.3633366716197643 0.028888995148983132 6.216062327135458 0.00042148380137744027 3.375219111685919 1.4217296245640387 MNYMQNHQAGAPAPS(ph)LSR ddPTM_PC-9_Lapatinib_30min_R1 2 MNYMQNHQAGAPAPSLSR 18 0 H0YJG4;Q9HCK8-2;Q9HCK8;A0A2R8Y840 H0YJG4 CHD8 Chromodomain-helicase-DNA-binding protein 8 1 MNYMQNHQAGAPAPS(0.58)LS(0.42)R;MNYMQNHQAGAPAPS(0.525)LS(0.475)R 53.342 0.033875 7290300.0 26770.0 22289.6 25177.0 21101.5 19510.9 20675.6 18573.0 20081.7 18478.5 12152.9 True False 26388.254890983248 22237.98980066894 23107.044246030488 22653.374702540474 18363.307221905274 19791.352785177645 19534.619061613044 21014.769093850133 16397.256742768568 14253.512572278642 1.8513510095964143 1.560176110127348 1.6211473578078497 1.5893187442510521 1.2883355684282123 1.388524595942016 1.370512634170297 1.474357214566276 1.1504011140846258 1.0 13.799029873994623 -1.5228787453571655 0.10283687389376113 0.7849026924302257 3.6705097379698257 0.8141457440512204 0.10080648406706927 53.55329213986985 0.39015625398238685 1.2006993071383711 21.82524334809037 0.029999999994692914 1.5228787453571655 2.8856070455396 MNYMQNHQAGAPAPSLS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 MNYMQNHQAGAPAPSLSR 18 0 H0YJG4;Q9HCK8-2;Q9HCK8;A0A2R8Y840 H0YJG4 CHD8 Chromodomain-helicase-DNA-binding protein 8 1 MNYMQNHQAGAPAPS(0.272)LS(0.728)R 60.761 0.01286 11471000.0 35029.0 28431.0 33505.0 31021.0 31680.0 25852.0 16702.0 21903.0 27139.0 17615.0 True False 34529.48003646812 28365.16976629543 30750.34823304014 33302.387823022436 29816.644685276406 24746.370223955397 17566.74783648635 22920.693340832677 24082.32003366053 20659.729279487896 1.6713423283213527 1.372969092797257 1.488419708556915 1.6119469608000556 1.4432253337840197 1.1978070907504552 0.8502893527229116 1.1094382230646938 1.165664840418348 1.0 14.33453372912032 -6.828072406475228 2.9873107902622884 1.0386103750303255 1.520437291702635 0.8214306599586387 0.10796749519524165 0.1064797133958469 1.9271418152583057 0.04060538093280783 0.03632420782035484 1.4856879246706704e-07 6.828072406475228 0.4818269166723095 MNYT(ph)ESSPLRES(ph)T(ph)AIGFTPELESIIPVPS(ph)NK ddPTM_PC-9_Lapatinib_30min_R1 1 MNYTESSPLRESTAIGFTPELESIIPVPSNK 31 1 Q8NE79 Q8NE79 BVES Blood vessel epicardial substance 4 MNY(0.319)T(0.342)ES(0.342)S(0.234)PLRES(0.794)T(0.873)AIGFT(0.066)PELES(0.09)IIPVPS(0.941)NK 44.931000000000004 0.006337399999999999 3496800.0 7634.1 7507.6 6991.0 8895.6 10239.0 7533.9 5084.0 7521.3 9772.6 6665.5 True False 7525.23633407752 7490.216613465568 6416.2269660404045 9549.812098851691 9636.762150648525 7211.692659378677 5347.224643796949 7870.767055855582 8671.906877959793 7817.622793779535 0.9625990576144623 0.9581194707201167 0.8207388787222866 1.2215749404602196 1.2326972539934358 0.9224917663099587 0.68399624602657 1.006798007972236 1.1092767081138797 1.0 12.932514259840286 -9.828429476512204 15.218958053656369 1.0000299780576978 0.9882733398237031 4.328969104527847e-05 0.15990798964181568 0.0 0.0 0.16730778274809605 0.04057809766225249 1.4844669176307326e-10 9.828429476512204 -0.011756638233994643 MPCES(ph)SPPESADTPTSTR ddPTM_PC-9_AZD4547_30min_R2 1 MPCESSPPESADTPTSTR 18 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 MPCES(0.5)S(0.5)PPESADTPTSTR 243.99 2.4621e-53 5833400.0 6026.4 8752.8 8603.7 14305.0 11272.0 5737.6 4465.8 7766.3 6550.2 6087.6 True False 7942.669843093009 11581.971429667035 8489.609316442282 11007.203260046857 9707.077368882918 5378.826964983106 4863.247548599061 6566.196786819865 6896.430199501664 5874.474976921234 1.352064631187807 1.9715755833786963 1.4451690320913784 1.8737339597649705 1.6524161575321443 0.9156268408861462 0.827860799085036 1.1177504053751468 1.173965371645183 1.0 12.5202442032267 -6.75561463992338 24.942950462200777 1.0032013118217795 1.6764088385971576 0.7435129585216942 0.19131466413438386 65.53805504355272 280649.6623738066 0.06165128519390763 0.06007389364779382 1.755437453407739e-07 6.75561463992338 0.6732075267753781 MPCES(ph)SPPESADTPTSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 MPCESSPPESADTPTSTR 18 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 MPCES(0.44)S(0.44)PPES(0.12)ADTPTSTR;MPCES(0.621)S(0.374)PPES(0.005)ADTPTSTR;MPCES(0.934)S(0.051)PPES(0.015)ADTPTSTR 230.96 9.013399999999997e-97 30979000.0 66706.6 83014.0 73740.7 102180.0 113038.0 87926.0 94273.0 87839.4 77756.0 55472.4 True False 77998.7098645945 91255.0812995867 75498.957951162 96455.18587202975 90889.01535007257 83315.00577512331 85342.77896258552 85533.70882353761 78893.03440010044 65529.10700072323 1.1902910543818892 1.3925885072503665 1.1521438549487442 1.471944152557507 1.3870021965821915 1.2714198253030335 1.3023644433555857 1.3052781082854312 1.2039387992763235 1.0 15.999848251054607 -8.692538075493601 1.5360385950028912 0.9999207281310996 1.3158879186046826 0.5267380982229593 0.08949771923414908 0.5031359735583744 2.3377343761246334 0.08301678400635208 0.024109534218958888 2.02984055174767e-09 8.692538075493601 0.315967190473583 MPCES(ph)SPPESADTPTSTR ddPTM_PC-9_Lapatinib_30min_R1 2 MPCESSPPESADTPTSTR 18 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 MPCES(0.861)S(0.107)PPES(0.032)ADTPTSTR;MPCES(0.891)S(0.109)PPESADTPTSTR 158.65 1.7031999999999998e-06 9528800.0 38604.0 44709.0 41933.0 22741.3 30523.0 32132.0 42316.0 35911.0 29653.0 23471.0 True False 38053.49988089345 44605.479057412784 38485.43060606096 24413.771064752895 28727.69715052687 30757.7892633504 44506.915426221814 37579.55615955086 26313.16688006689 27527.93107685838 1.3823596032207262 1.620371648449484 1.3980502384508695 0.8868727183524725 1.0435835904383344 1.1173302191680956 1.6167911530277328 1.3651427727942287 0.9558715766397463 1.0 14.748608564589382 -5.536484325716813 24.86370644786605 1.1686363618407267 1.503327003336264 0.33881360788122483 0.2095610627741709 257.6695662733706 470880.05346502917 0.06134488648596189 0.1063201738217367 2.9074728922329045e-06 5.536484325716813 0.3346906414955373 MPCESS(ph)PPESADTPTSTR ddPTM_PC-9_AZD4547_30min_R2 3 MPCESSPPESADTPTSTR 18 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 MPCES(0.046)S(0.949)PPES(0.001)ADT(0.001)PT(0.001)S(0.001)T(0.001)R;MPCES(0.043)S(0.952)PPES(0.005)ADTPTSTR;MPCES(0.101)S(0.891)PPES(0.008)ADTPTSTR 145.94 4.0171e-05 54028200.0 82480.0 129372.0 122461.0 167792.0 130299.0 108799.0 84157.0 116582.0 88222.0 109520.0 True False 108706.92430942354 171188.96899265214 120837.08712540417 129110.14676055795 112209.23297445683 101995.78133073018 91646.80996628862 98566.93068784804 92885.23481121736 105685.73813529332 1.0285865077676106 1.619792528425217 1.1433622857486683 1.2216420970185962 1.0617254035810628 0.9650855747457671 0.8671634563309498 0.9326417398123089 0.8788814503269171 1.0 16.689421178407024 -6.327979062840688 1.2770653773603038 0.9113006258430029 1.3078417748652669 0.5297099903093219 0.14463885329233492 0.3141416490029765 1.0474573868909944 0.05583213075616293 0.07510138078438076 4.6991676255403183e-07 6.327979062840688 0.396541149022264 MPCESS(ph)PPESADTPTSTR ddPTM_PC-9_Lapatinib_30min_R1 2 MPCESSPPESADTPTSTR 18 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 MPCES(0.048)S(0.952)PPESADTPTSTR;MPCES(0.157)S(0.843)PPESADTPTSTR 218.34 1.1256999999999999e-27 16697100.0 32696.5 48824.0 32369.6 12750.8 18614.5 25170.2 48415.9 40723.4 29026.9 15589.6 True False 32230.241914196235 48710.95102773761 29708.296438269397 13688.536367421886 17519.631707515073 24093.72922060199 50922.63840118189 42615.55783208082 25757.5848551922 18284.24158816373 1.762733321958534 2.6640946955804035 1.6248033201169803 0.7486521276487144 0.9581820292101354 1.317731944441109 2.7850560908223048 2.330726031298335 1.408731378383576 1.0 14.158313165939582 MPCKRCRPS(ph)VY(ph)SLSY(ph)IK ddPTM_PC-9_Lapatinib_30min_R1 1 MPCKRCRPSVYSLSYIK 17 3 Q9UMX2 Q9UMX2 OAZ3 Ornithine decarboxylase antizyme 3 3 MPCKRCRPS(1)VY(0.843)S(0.184)LS(0.433)Y(0.541)IK 50.493 0.039025 0.0 4876.1 5012.2 13033.0 5572.2 11146.0 10460.0 6888.2 10191.0 13565.0 7897.2 True False 4806.5659198327785 5000.594558848648 11961.477048834871 5981.998176314288 10490.41419387913 10012.65018345093 7244.837291778552 10664.51106407459 12037.16685421736 9262.220497642453 0.5189431541881573 0.5398915476177087 1.2914265053266083 0.6458492515738432 1.1326025110878428 1.0810204945994848 0.7821922716720691 1.1513989617056803 1.2995983908266084 1.0 13.177142387100883 -5.239530360939965 23.487913276402576 1.033761716915036 0.5294169280917181 0.5313959613463249 0.19442846154017934 286.6890799153594 307346.5441820278 0.04847700172792468 0.12793968613094242 5.760625453985696e-06 5.239530360939965 -0.5043447888233178 MPCQSLQPEPINT(ph)PTHTK ddPTM_PC-9_AZD4547_30min_R2 2 MPCQSLQPEPINTPTHTK 18 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 MPCQSLQPEPINT(0.826)PT(0.17)HT(0.005)K;MPCQSLQPEPINT(0.97)PT(0.029)HT(0.002)K 130.17 4.1463e-05 31130000.0 46736.0 47727.0 51298.0 78930.0 62155.0 60709.0 52103.0 76644.0 49655.0 61177.0 True False 61597.07583081029 63153.8193976463 50617.75500248225 60733.90795634374 53525.85112339586 56912.85663294049 56740.06606311453 64800.430903908076 52279.66192730839 59035.211850829546 1.043395524461809 1.0697652708899168 0.8574163353624178 1.0287742866038403 0.906676700994065 0.9640493334172862 0.9611224265017563 1.0976572942203733 0.8855674484476974 1.0 15.849288093508877 -5.146021238550924 21.059855174395203 0.9662876784843891 1.0565982478190625 0.23898629395977222 0.06678521033161786 9.113010620341297 1644.1858005095469 0.016090478096273626 0.042571806014701556 7.144613855082434e-06 5.146021238550924 0.09031056933467341 MPCQSLQPEPINT(ph)PTHTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 MPCQSLQPEPINTPTHTK 18 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 MPCQSLQPEPINT(0.96)PT(0.033)HT(0.007)K;MPCQSLQPEPINT(0.998)PT(0.002)HTK;MPCQSLQPEPINT(0.995)PT(0.005)HTK;MPCQSLQPEPINT(0.994)PT(0.006)HTK 132.65 3.9853e-06 24737900.0 70359.3 60943.6 63056.8 67140.1 73519.0 69728.9 66966.9 50211.4 51662.7 53464.1 True False 82269.73983048093 66993.67784577893 64560.31325624568 63378.45786814113 59113.479710557425 66072.19373328701 60623.31043362957 48893.40395337589 52418.169251273954 63156.71810841725 1.3026284818861793 1.060752994333477 1.022224003872699 1.0035109449376902 0.935980866027284 1.0461625573999103 0.9598869645120139 0.7741599851569804 0.8299698087745933 1.0 15.946648584127454 -1.5228787452803714 0.44853860522017797 0.8989034712148865 9.318305777199006 0.6922217837788165 0.07507244432684444 53.26445851265872 0.6437267535173816 0.050759715347735906 410.3274582721885 0.029999999999997664 1.5228787452803714 8.41940230598412 MPCQSLQPEPINT(ph)PTHTK ddPTM_PC-9_Lapatinib_30min_R1 2 MPCQSLQPEPINTPTHTK 18 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 MPCQSLQPEPINT(0.976)PT(0.022)HT(0.001)K;MPCQSLQPEPINT(0.999)PT(0.001)HTK 108.14 0.00027885 23532000.0 56757.0 34918.0 46836.0 37546.0 34013.0 35428.0 32244.0 22463.7 32282.0 22919.0 True False 55947.6347720409 34837.149516355516 42985.3248721883 40307.25808978434 32012.422212130874 33912.8270267017 33913.4365488963 23507.445509768666 28646.06121546958 26880.51861235214 2.0813450655052406 1.2959999030802605 1.5991255783448937 1.4994970398845782 1.1909153492827522 1.26161356913397 1.2616362443733653 0.8745160704959956 1.0656811212826132 1.0 14.714273352199267 -1.5228787452891857 0.24131565433131164 0.9338036794461257 6.6645392331134135 0.731468266848436 0.17020967874487797 26.579485179298143 0.3559912584358036 0.22869747310988153 61.10945994902304 0.029999999999388797 1.5228787452891857 5.730735553667287 up MPDEPEEPVVAVS(ph)SPAVPPPTK ddPTM_PC-9_AZD4547_30min_R2 3 MPDEPEEPVVAVSSPAVPPPTK 22 0 O60885;O60885-2;O60885-3;M0QZD9 O60885 BRD4 Bromodomain-containing protein 4 1 MPDEPEEPVVAVS(0.5)S(0.5)PAVPPPTK;MPDEPEEPVVAVS(0.499)S(0.499)PAVPPPT(0.002)K;MPDEPEEPVVAVS(0.519)S(0.481)PAVPPPTK 89.62200000000001 0.00014381 19592100.0 133753.0 137178.0 167059.0 216842.0 197510.0 180374.0 143498.0 196363.0 159535.0 168695.0 True False 176283.67176477134 181518.10583800217 164843.68850558868 166852.42707550357 170089.14577076526 169095.18526594102 156269.0440075391 166019.610322845 167967.69440284226 162789.03939676203 1.082896443261878 1.1150511515433923 1.012621544524376 1.0249610642940028 1.0448439673890504 1.0387381478049587 0.9599481917616586 1.0198451378425373 1.031812061950058 1.0 17.31264404050127 -5.266292349708363 24.989274106846075 1.0173802427589171 1.0989738001855862 0.6587366166213774 0.023711516801104747 226.4286967729354 1165949.8664442643 0.006453043789562236 0.014127820102248249 5.4163615981346394e-06 5.266292349708363 0.08159355742666907 MPDEPEEPVVAVS(ph)SPAVPPPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MPDEPEEPVVAVSSPAVPPPTK 22 0 O60885;O60885-2;O60885-3;M0QZD9 O60885 BRD4 Bromodomain-containing protein 4 1 MPDEPEEPVVAVS(0.487)S(0.487)PAVPPPT(0.025)K 72.968 0.00085013 7689600.0 55228.0 61888.0 57293.0 64677.0 69062.0 68188.0 66508.0 52342.0 55106.0 49317.0 True False 64577.00959727849 68031.83163645674 58659.08240491243 61053.35737566319 55529.7968657152 64612.101241886456 60207.8807637779 50968.07796093324 55911.8209996904 58257.7817068428 1.108470108289301 1.1677724356000654 1.0068883621434301 1.0479863047804998 0.9531738977832179 1.10907245948737 1.0334736236053088 0.8748715874114148 0.9597313759909802 1.0 15.830163148287134 -4.496020103029686 0.3662775019648039 0.9591588133528793 1.3224620305225099 0.42070460177761004 0.06272482068837394 7.642590187539948 0.6968506697434238 0.05897571219435474 1.2792829146895075 3.191390125626864e-05 4.496020103029686 0.36330321716963054 MPDEPEEPVVAVSS(ph)PAVPPPTK ddPTM_PC-9_AZD4547_30min_R2 1 MPDEPEEPVVAVSSPAVPPPTK 22 0 O60885;O60885-2;O60885-3;M0QZD9 O60885 BRD4 Bromodomain-containing protein 4 1 MPDEPEEPVVAVS(0.221)S(0.777)PAVPPPT(0.002)K 73.649 0.00074115 4912200.0 41009.0 39329.0 48379.0 69347.0 63261.0 51579.0 45865.0 59280.0 41598.0 51934.0 True False 54049.008959810395 52041.33012948712 47737.462849722964 53360.12055046974 54478.302114345504 48353.7569762381 49946.8961477218 50119.63811888305 43796.78535599988 50115.80646747931 1.0784822747466587 1.038421484113147 0.9525430440932906 1.0647363439136852 1.0870482978199116 0.9648404442541572 0.9966295998874702 1.0000764559462136 0.8739116147800611 1.0 15.612978079091778 -7.371116817527591 1.2422127206564801 0.950261856986753 1.0370086732878214 0.3311145892576849 0.0507336696644446 0.5895330537427518 1.74350723098993 0.03561711751782379 0.018626031851782795 4.254839500896663e-08 7.371116817527591 0.0867468163010684 MPDEPEEPVVAVSS(ph)PAVPPPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MPDEPEEPVVAVSSPAVPPPTK 22 0 O60885;O60885-2;O60885-3;M0QZD9 O60885 BRD4 Bromodomain-containing protein 4 1 MPDEPEEPVVAVS(0.454)S(0.54)PAVPPPT(0.006)K;MPDEPEEPVVAVS(0.314)S(0.676)PAVPPPT(0.011)K 70.11399999999999 0.0013069000000000002 12006800.0 50236.0 51999.0 50586.0 60775.0 63188.0 57924.0 59336.0 47670.0 51591.0 44480.0 True False 58739.96259377282 57161.117070581 51792.16208847334 57369.973785208465 50806.76499885333 54886.36347062574 53715.264524561324 46418.71301054002 52345.42077441707 52543.87189651375 1.1179222328621385 1.0878740946834107 0.9856936730981508 1.0918489961721858 0.9669398764316096 1.0445816322543868 1.0222936107631095 0.8834277211615208 0.9962231347836806 1.0 15.681234894449668 -2.0485942954659806 0.30429002132412886 0.9658161450840331 1.9598278787962702 0.43715789692349993 0.04952417633433048 36.483294166601254 0.6989591198388014 0.04995013719174528 18.70547048964162 0.008941403721160783 2.0485942954659806 0.9940117337122371 MPDEPEEPVVAVSS(ph)PAVPPPTK ddPTM_PC-9_Lapatinib_30min_R1 1 MPDEPEEPVVAVSSPAVPPPTK 22 0 O60885;O60885-2;O60885-3;M0QZD9 O60885 BRD4 Bromodomain-containing protein 4 1 MPDEPEEPVVAVS(0.135)S(0.864)PAVPPPT(0.001)K 128.38 4.7725e-06 3013700.0 24218.0 23262.0 27975.0 26176.0 24697.0 22345.0 22188.0 21758.0 25379.0 19662.0 True False 23872.64687896271 23208.138268213028 25675.003486622838 28101.070360576225 23244.371016170175 21389.35643873911 23336.7860732822 22768.956111484164 22520.549767282148 23060.550502031845 1.0352158278640968 1.0064000105360962 1.1133733986255288 1.2185776032580082 1.0079712110134635 0.9275301748262476 1.0119787067193395 0.9873552719167745 0.9765833545603294 1.0 14.49313933300191 -6.503627458490762 24.964112490880563 0.9802876518580403 1.0916889283873532 0.4783816927838235 0.05592341793288194 714.8312120982997 926959.1517673702 0.01881601353867392 0.021013151331027144 3.135974636644415e-07 6.503627458490762 0.11140127652931286 MPEANQLHLPNLNS(ph)QVDSPSSEKSPVMTPFK ddPTM_PC-9_AZD4547_30min_R2 1 MPEANQLHLPNLNSQVDSPSSEKSPVMTPFK 31 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-3 E7EPK0 LIMCH1 LIM and calponin homology domains-containing protein 1 1 MPEANQLHLPNLNS(0.579)QVDS(0.086)PS(0.086)S(0.105)EKS(0.13)PVMT(0.014)PFK 78.921 2.5048e-07 17313000.0 30362.0 34268.0 40262.0 39137.0 48552.0 46590.0 48078.0 53718.0 43052.0 39117.0 True False 40016.484431167846 45344.46085273628 39728.099573276515 30114.569310622435 41811.39286852412 43676.719934914065 52356.848860572754 45417.11741683806 45327.64082760003 37747.52573628814 1.0601088058256085 1.201256505380561 1.0524689711009159 0.7977892252066776 1.1076591658120052 1.157075042217296 1.3870273041562593 1.2031813087334848 1.2008109125951225 1.0 15.204094461736194 -6.742664630086758 3.3824163603245094 1.2186945235945574 1.0348607321208672 0.24455840529137185 0.1286662336514228 0.31427900785354684 7.511161778735935 0.04763781394745402 0.04492004107107535 1.8085701969376385e-07 6.742664630086758 -0.18383379147369028 MPEANQLHLPNLNS(ph)QVDSPSSEKSPVMTPFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MPEANQLHLPNLNSQVDSPSSEKSPVMTPFK 31 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-3 E7EPK0 LIMCH1 LIM and calponin homology domains-containing protein 1 1 MPEANQLHLPNLNS(0.531)QVDS(0.108)PS(0.108)S(0.108)EKS(0.108)PVMT(0.035)PFK 63.803000000000004 5.1912e-05 20119000.0 14785.0 21697.0 22903.0 27686.0 49246.0 43666.0 58701.0 48481.0 44022.0 49784.0 True False 17287.80848293914 23850.934769522428 23449.094380111193 26134.84317922307 39596.599815368914 41376.07809040024 53140.41632156317 47208.42511986557 44665.73846855825 58809.44511007286 0.2939631287216157 0.40556299629899495 0.39873007365095575 0.4443987378270077 0.6733034080028554 0.7035617835359129 0.9036034300629934 0.8027354284929263 0.7594994032839109 1.0 15.843760257726172 -6.416535941592082 0.9571472385460476 0.8631955356143904 0.33489574012728424 0.9076034812863292 0.0690583308516053 0.15506273343380828 0.30632793664856106 0.03425779438872012 0.045507751914977225 3.8323402318629347e-07 6.416535941592082 -0.5282997954871063 down MPEANQLHLPNLNSQVDS(ph)PSSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MPEANQLHLPNLNSQVDSPSSEK 23 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3 E7EPK0 LIMCH1 LIM and calponin homology domains-containing protein 1 1 MPEANQLHLPNLNS(0.061)QVDS(0.818)PS(0.091)S(0.031)EK 92.449 1.0148e-05 6049900.0 52145.0 55967.0 50109.0 48407.0 57464.0 44430.0 54701.0 44095.0 39407.0 48013.0 True False 60972.11858930415 61523.033886982565 51303.78859944073 45694.91272761145 46204.341708775544 42100.012585455144 49519.325279055374 42937.552972514415 39983.252824280426 56717.376829301145 1.0750165469183852 1.0847298892567743 0.9045515055085611 0.805659839754872 0.8146417251953304 0.7422771457178107 0.8730891315388349 0.757044055505969 0.7049559598747946 1.0 15.791503189227159 -5.4237762156168365 2.3811000305890437 0.802775279534452 1.088489348186536 0.6458643894425045 0.07744809109657466 0.16869170717942542 1.8363541869563895 0.020705420857855598 0.05527806246503001 3.768979579101827e-06 5.4237762156168365 0.28571406865208404 MPEANQLHLPNLNSQVDSPS(ph)SEKSPVMTPFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MPEANQLHLPNLNSQVDSPSSEKSPVMTPFK 31 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-3 E7EPK0 LIMCH1 LIM and calponin homology domains-containing protein 1 1 MPEANQLHLPNLNS(0.043)QVDS(0.043)PS(0.295)S(0.295)EKS(0.295)PVMT(0.027)PFK 59.893 0.00025324 25932000.0 24211.0 28720.0 43558.0 53337.0 80141.0 71795.0 86541.0 76537.0 71050.0 73483.0 True False 28309.444110952965 31571.13179613235 44596.587914634925 50348.700810887116 64437.94634698212 68029.94381212578 78343.20997741778 74527.98484765466 72088.97183660585 86804.88620889225 0.32612731088463726 0.36370224275345253 0.5137566542891968 0.5800215058139138 0.742330865936682 0.7837109958120864 0.9025207381631513 0.8585690057620288 0.8304713592173466 1.0 16.40548863317465 -5.758793665576105 0.5306870790480546 0.9292333886458558 0.17298390863094895 0.9659600187191557 0.04054635197791875 0.281549270066491 0.12263183844528756 0.02875223558548451 0.11848744307731975 1.742634606924817e-06 5.758793665576105 -0.7562494800149069 down MPEANQLHLPNLNSQVDSPSSEKS(ph)PVMTPFK ddPTM_PC-9_AZD4547_30min_R2 1 MPEANQLHLPNLNSQVDSPSSEKSPVMTPFK 31 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-3 E7EPK0 LIMCH1 LIM and calponin homology domains-containing protein 1 1 MPEANQLHLPNLNS(0.015)QVDS(0.227)PS(0.227)S(0.227)EKS(0.296)PVMT(0.007)PFK 71.297 1.0545e-05 13858000.0 17511.0 21159.0 23956.0 21752.0 22817.0 23182.0 20279.0 29481.0 26503.0 24625.0 True False 23079.133748573222 27998.2329632032 23638.32778742766 16737.412465049925 19649.253400088866 21732.425875320423 22083.791714371528 24925.388855985017 27903.89447305314 23762.886245266644 0.9712260333346662 1.17823368231543 0.9947582774014334 0.7043509905445038 0.8268883332302626 0.914553293358854 0.9293396217292595 1.0489209348864317 1.1742636893955316 1.0 14.536422456380228 -7.847224832437099 3.9882955726009257 1.093764926851112 0.929532869929644 0.23120367163955757 0.1203579663830393 0.359431790132079 10.70783869973008 0.08005019378393406 0.03645418588147019 1.421592644023328e-08 7.847224832437099 -0.16423205692146803 MPETVPQEEMPGPPLNS(ph)ESGEEAPTGR ddPTM_PC-9_AZD4547_30min_R2 1 MPETVPQEEMPGPPLNSESGEEAPTGR 27 0 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 MPETVPQEEMPGPPLNS(0.499)ES(0.499)GEEAPT(0.001)GR 73.23899999999999 0.0012925 0.0 2797.6 2100.9 4015.0 7056.1 3623.5 3872.5 3244.2 4285.1 3348.4 3907.9 True False 3687.1786063050927 2779.9748396613054 3961.7584766456052 5429.425160658273 3120.4395711628163 3630.351962823669 3532.927515151838 3622.9362568020574 3525.389588105917 3771.0856104721875 0.9777499073651132 0.7371815776182332 1.0505617972829695 1.4397512338571492 0.8274645270575276 0.9626808664174302 0.9368462771942935 0.9607144019062511 0.9348474026460761 1.0 11.880764187303349 MPETVPQEEMPGPPLNS(ph)ESGEEAPTGR ddPTM_PC-9_Lapatinib_30min_R1 1 MPETVPQEEMPGPPLNSESGEEAPTGR 27 0 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 MPETVPQEEMPGPPLNS(0.791)ES(0.206)GEEAPT(0.003)GR 79.365 0.00019413 0.0 9530.2 7322.4 10118.0 8447.7 8194.2 9924.6 8548.5 9816.3 8261.6 8013.9 True False 9394.29760037536 7305.445432686916 9286.137096609464 9068.972038701091 7712.233266417045 9500.147993372579 8991.099501868253 10272.401134164993 7331.09160949518 9399.091937149475 0.9994899148975056 0.7772501302825311 0.987982366669533 0.9648774689453138 0.8205296126463878 1.0107516829177599 0.9565923561542525 1.092914209463555 0.7799787105517482 1.0 13.198305666872285 -6.801839311510573 24.999951954982908 0.9731385682883668 0.9100272278405587 0.07885797192023725 0.09838483350425749 391.6431411553476 242350.65733848355 0.033019130234880505 0.02912045701326328 1.578195092166082e-07 6.801839311510573 -0.06311134044780808 MPETVPQEEMPGPPLNSES(ph)GEEAPTGR ddPTM_PC-9_Lapatinib_30min_R1 2 MPETVPQEEMPGPPLNSESGEEAPTGR 27 0 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 MPETVPQEEMPGPPLNS(0.276)ES(0.685)GEEAPT(0.039)GR;MPETVPQEEMPGPPLNS(0.195)ES(0.772)GEEAPT(0.033)GR 91.432 5.0246999999999995e-05 0.0 11775.3 9619.9 11213.5 9428.3 11452.3 9779.900000000001 9049.0 11766.9 13189.0 10210.5 True False 11607.382062674445 9597.62571259489 10291.569315361765 10121.688633886795 10778.698230088097 9361.6364750604 9517.512942902951 12313.633131180382 11703.5159336729 11975.371320363958 0.9692711609648587 0.8014470245506506 0.8593945891148351 0.8452087507862909 0.9000721515631892 0.7817408099188593 0.794757230343125 1.0282464569796859 0.977298792712275 1.0 13.547782769852644 -7.767561957461278 24.99969173806626 1.0020795079006364 0.8478284002233352 0.6304571664504557 0.05315720652853511 93.58798357511043 382129.9533430646 0.027697910017939968 0.013840243114135524 1.707804063378512e-08 7.767561957461278 -0.1542511076773012 MPFIT(ph)CDEFNGVPS(ph)Y(ph)MK ddPTM_PC-9_Lapatinib_30min_R1 1 MPFITCDEFNGVPSYMK 17 0 K7EPW0 K7EPW0 SKA1 3 MPFIT(1)CDEFNGVPS(1)Y(1)MK 44.541000000000004 0.045659 0.0 2962.5 4722.8 5587.1 3783.6 6466.3 4351.7 4645.3 3303.1 5644.3 3275.2 True False 2920.254206744036 4711.864646767969 5127.750204829686 4061.858565719596 6085.964947234939 4165.587935308168 4885.810904372535 3456.574084559397 5008.5794968860355 3841.3139560703235 0.7602227363189717 1.2266283622357756 1.3348948467819044 1.0574138464523972 1.5843445802229872 1.0844174631249297 1.271911372058413 0.8998415969350975 1.3038714237275801 1.0 11.907384166874042 -11.075220894958187 8.890634563303763 0.9999814269779496 1.1773556103348728 0.04874437920684904 0.22178161961091372 7.846256642644154e-05 3.950644166116566e-06 0.2063625810220809 0.05004504402169222 8.409672921249533e-12 11.075220894958187 0.17737418335692323 MPFLSIS(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 1 MPFLSISSPK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 MPFLS(0.014)IS(0.493)S(0.493)PK 64.82 0.0444 42335000.0 31845.0 30965.0 34025.0 47378.0 44848.0 39532.0 42680.0 50469.0 51098.0 44864.0 True False 41971.04758285159 40973.83069642171 33573.806268459935 36455.7340828032 38621.629332830154 37060.05779066373 46478.43731788435 42670.175712245444 53798.93596136546 43293.32501553882 0.9694577066507911 0.9464237427297487 0.7754961360997252 0.8420636222724525 0.8920920100031147 0.8560224417358139 1.0735705169608094 0.9856063422462996 1.2426612172212683 1.0 15.401856986272389 -7.265481341281649 24.074877134491043 1.0742600698997076 0.8773064723573881 0.5759682415278712 0.08202532457840409 155.66664572032494 927178.4272452546 0.033427748294773074 0.023491378174795 5.4264856479408244e-08 7.265481341281649 -0.19695359754231945 MPFLSIS(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MPFLSISSPK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 MPFLSIS(0.706)S(0.293)PK;MPFLS(0.005)IS(0.788)S(0.207)PK 105.2 0.0024954 71212300.0 103115.0 102429.0 83329.0 97693.0 115926.0 83810.0 104889.0 116244.0 83081.0 83382.0 True False 120570.33288591633 112597.4741903219 85315.87938699221 92219.57793497948 93211.13248175394 79414.85606092714 94953.15458940128 113192.71817069908 84295.90245118998 98498.49654845102 1.2240829770087736 1.1431390136491641 0.8661642804367645 0.9362536603755879 0.9463203576503704 0.8062544997513063 0.9640061312275381 1.1491821919842202 0.8558090265847373 1.0 16.587814083421534 -5.116546993057733 4.519859210506216 0.9424713320547278 1.2069647757563104 0.549736712834742 0.08908483248789396 0.1622664813796722 5.157002577902283 0.023547515204841284 0.07014778573650726 7.646329464611916e-06 5.116546993057733 0.2644934437015827 MPFLSIS(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 1 MPFLSISSPK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 MPFLS(0.01)IS(0.606)S(0.384)PK 124.67 0.00035669 27970000.0 71516.0 75978.0 61543.0 66863.0 74377.0 61356.0 72585.0 63284.0 67267.0 70532.0 True False 70496.16872557187 75802.07760907443 56483.17210285004 71780.32806842934 70002.29109080824 58731.94690782175 76343.0961388673 66224.40566960037 59690.682107087305 82723.36222201757 0.8521917730612825 0.9163321650978424 0.6827958944809007 0.8677153120998793 0.8462215414181569 0.7099801716254434 0.9228722586731115 0.8005526358063592 0.7215698262709164 1.0 16.33600720352984 -10.580325774850452 4.88530495460189 1.0000045994796238 0.8149166092579011 0.32698379196922156 0.08030203091422457 3.894487037175468e-06 7.513656282605568e-07 0.07527182420315867 0.018255645361364054 2.6282957037446026e-11 10.580325774850452 -0.18508799022172273 MPFLSISS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 MPFLSISSPK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 MPFLSIS(0.027)S(0.973)PK;MPFLSIS(0.029)S(0.971)PK;MPFLS(0.009)IS(0.214)S(0.777)PK 163.12 0.00011981 91834000.0 227518.0 252821.0 238613.0 299088.0 273052.0 293066.0 319651.0 390611.0 357186.0 329507.0 True False 299863.9913316131 334540.444065882 235448.83571303534 230137.88246353663 235143.44302060158 274740.5366912536 348099.31975396164 330251.0452978243 376066.12275032897 317971.0602241257 0.9430543494123346 1.052109722910246 0.7404725308871708 0.7237699000070045 0.7395120891028822 0.8640425845597378 1.0947515774190257 1.0386198198824854 1.1827055030896658 1.0 18.2785359406664 -7.229465075580965 5.300509793449827 1.0830148009474607 0.8368685662934764 0.5503209239086055 0.10415518932835213 0.16168275469185683 12.923399652057405 0.04584617482125713 0.0342004121475202 5.895693862343231e-08 7.229465075580965 -0.24614623465398433 MPFLSISS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MPFLSISSPK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 MPFLSIS(0.029)S(0.971)PK;MPFLS(0.001)IS(0.23)S(0.769)PK 123.62 0.00044006 65622700.0 138343.0 140751.0 111331.0 133328.0 156725.0 115343.0 146862.0 178126.0 112595.0 112086.0 True False 161761.73750120038 154723.8290890472 113985.5532651686 125858.06441520792 126015.86130982629 109294.21003025325 132950.1681711967 173450.38124009766 114241.48886618765 132406.3045277122 1.2217072146088344 1.1685533377050337 0.8608770833968241 0.9505443480515404 0.9517361107488019 0.8254456645406816 1.0041075358565776 1.30998581871753 0.8628100397007703 1.0 17.014612292158382 -5.120728426079823 5.924716652537365 0.9768125736461546 1.2085525950249516 0.33231805566455996 0.12781220975980778 0.2635101362592906 11.449355352626922 0.03407903344292982 0.09425994479863513 7.5730630732830426e-06 5.120728426079823 0.231740021378797 MPFLSISS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 MPFLSISSPK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 MPFLSIS(0.054)S(0.946)PK;MPFLS(0.002)IS(0.374)S(0.624)PK;MPFLS(0.001)IS(0.155)S(0.844)PK 179.57 0.00036178 40474000.0 122133.0 124236.0 99040.0 113034.0 128137.0 99159.0 131685.0 105608.4 108292.0 118386.0 True False 120391.36102355075 123948.33917503737 90897.3135054556 121346.8974303704 120600.23358703466 94918.20072091876 138503.0049603463 110515.35180641912 96095.01459468537 138848.86236057052 0.867067680474844 0.8926853059347463 0.6546493212843787 0.8739495258898843 0.8685719964622627 0.6836080548822204 0.9975091088659691 0.7959399157295697 0.692083557336901 1.0 17.08315583111473 -7.247395678553266 24.927516381509836 0.8543781607443373 0.8096114641371474 0.0639149627079677 0.11364642536632763 3346.5271897913576 5940079.906226183 0.04329526500484623 0.0333623377467437 5.6572363268191164e-08 7.247395678553266 -0.044766696607189904 MPFPVNHGASSEDTLLK ddPTM_PC-9_Lapatinib_30min_R1 2 MPFPVNHGASSEDTLLK 17 0 P09936;D6RE83;D6R956 P09936 UCHL1 Ubiquitin carboxyl-terminal hydrolase isozyme L1;Ubiquitin carboxyl-terminal hydrolase 0 ; 145.7 6.3143e-05 18106100.0 78755.0 80093.0 93208.0 85291.0 96266.0 91994.0 93341.0 83909.0 86110.0 68495.0 False True 77631.93925810176 79907.54957939924 85544.79803328465 91563.58466243511 90603.82314623785 88059.63106848807 98173.7402589793 87807.7184648644 76411.38502150067 80334.26948614948 0.9663614265078537 0.9946881958412056 1.064860595365637 1.1397823774101996 1.1278352778431495 1.09616520610386 1.2220655130984361 1.0930294011076236 0.9511679823599422 1.0 16.293727932309764 -5.300449603356217 2.7411565621378613 1.101282524155628 0.9727038442559055 0.26291423092874666 0.07070284738151075 0.3399617983812876 4.967360250986728 0.019636273304643143 0.05731588574929857 5.006686480299659e-06 5.300449603356217 -0.1285786798997226 MPFQTS(ph)PGGK ddPTM_PC-9_AZD4547_30min_R2 3 MPFQTSPGGK 10 0 I6LM39;A0A087X1U4;P51608;P51608-2 I6LM39 MECP2 Methyl-CpG-binding protein 2 1 MPFQT(0.064)S(0.936)PGGK;MPFQT(0.172)S(0.828)PGGK;MPFQT(0.068)S(0.932)PGGK 118.77 0.00084579 34772000.0 238839.0 236717.0 290779.0 304845.0 298134.0 310135.0 309696.0 368360.0 269479.0 328126.0 True False 314784.8338401847 313231.1409967658 286923.0804683765 234567.69505830025 256743.2402674367 290742.2094229355 337258.34403935133 311438.42607071076 283723.10978771764 316638.4086137819 0.9941460835982849 0.9892392472791508 0.9061537471859564 0.7408061962072737 0.8108404832864037 0.9182152307289001 1.0651213967245536 0.9835775370213732 0.8960476747904182 1.0 18.27247674114289 -7.012291850399629 24.505044275869597 0.9857967240977095 0.8844406071054428 0.2504312049961276 0.08005703129983262 724.2431709260735 1443851.2969300016 0.0333029686115871 0.027228001041120563 9.720937471420217e-08 7.012291850399629 -0.10135611699226665 MPFQTS(ph)PGGK ddPTM_PC-9_Lapatinib_30min_R1 2 MPFQTSPGGK 10 0 I6LM39;A0A087X1U4;P51608;P51608-2 I6LM39 MECP2 Methyl-CpG-binding protein 2 1 MPFQT(0.066)S(0.934)PGGK;MPFQT(0.002)S(0.998)PGGK 108.98 0.0019491 22677000.0 125993.0 139388.0 139336.0 119000.0 107051.0 148372.0 127570.0 105840.0 133957.0 96726.0 True False 124196.31671571337 139065.25564997326 127880.33193251373 127751.65697236262 100754.4706503637 142026.47543202483 134174.95039519595 110757.7127879162 118869.35203025401 113444.96022070642 1.094771565648137 1.2258389916962615 1.127245597192889 1.1261113470692978 0.8881352724206218 1.2519416918628494 1.1827316976810558 0.9763123242534336 1.0478151854343682 1.0 16.791632993309598 -6.367280578499863 0.11425047543545651 0.9175458980339691 1.298343461630719 0.14765447515647134 0.10092366096953077 45.9859117386996 1.7265128219925798 1.767324105773553 3.879646567373933 4.292590118568959e-07 6.367280578499863 0.3807975635967499 MPIEDS(ph)SPEKGR ddPTM_PC-9_Lapatinib_30min_R1 1 MPIEDSSPEKGR 12 1 O75376-2;O75376;A0A088AWL3 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 MPIEDS(0.539)S(0.461)PEKGR 55.18600000000001 0.038574000000000004 10025000.0 35572.0 37903.0 37515.0 37400.0 41907.0 39472.0 42459.0 36438.0 35247.0 37914.0 True False 35064.73675689413 37815.23793225338 34430.66151208778 40150.52076274259 39442.11265233201 37783.874573726105 44657.31926651747 38131.04250345896 31277.111692635423 44467.384382770564 0.7885495682646987 0.8504039186731513 0.7742902351915344 0.9029206759077875 0.8869897161663133 0.8496986071518506 1.0042713302431276 0.8575058558702476 0.7033719686187372 1.0 15.440459925930229 -5.768822251552701 24.993771035285977 0.8838641699227617 0.8090135059568093 0.17475629895566736 0.08132371663860201 318.203872665799 1077242.019979703 0.022855412190177622 0.034685311043982266 1.7028553119883386e-06 5.768822251552701 -0.07485066396595241 MPIEDSS(ph)PEKGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MPIEDSSPEKGR 12 1 O75376-2;O75376;A0A088AWL3 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 MPIEDS(0.146)S(0.854)PEKGR 81.565 0.028357999999999998 4674900.0 12013.0 17035.0 14728.0 13981.0 15089.0 12396.0 14140.0 9590.3 11091.0 9163.1 True False 14046.563632434767 18726.122219607056 15079.171376251034 13197.689897013575 12132.418767292815 11745.93193808917 12800.556835265217 9338.564786762787 11253.184892889452 10824.297494940307 1.2976882461887869 1.7300080885951596 1.3930854527325787 1.2192652597716096 1.1208504545411815 1.0851449660894548 1.1825762218054974 0.8627409576582675 1.0396226543246454 1.0 13.401985775544999 -5.926669124143174 1.4536633843230942 1.0367512771272607 1.5282311944115086 0.7013218025258732 0.12544299732061015 0.2173904164767123 0.9330238200970353 0.04265839793208126 0.08163081192018823 1.1839432228098767e-06 5.926669124143174 0.4914799172842479 MPIVGLGTWKS(ph)PLGK ddPTM_PC-9_AZD4547_30min_R2 1 MPIVGLGTWKSPLGK 15 1 O60218 O60218 AKR1B10 Aldo-keto reductase family 1 member B10 1 MPIVGLGT(0.01)WKS(0.99)PLGK 51.798 0.042457 4727100.0 15460.0 12474.0 23505.0 28275.0 27276.0 18866.0 13100.0 20193.0 17823.0 21926.0 True False 20375.958412023425 16505.97655763489 23193.308342105815 21756.6355943953 23489.19821803147 17686.30603760656 14265.874621937332 17072.63583897784 18765.08739362436 21158.377413754984 0.9630208410394026 0.7801154235439819 1.0961761333847806 1.028275239114101 1.110160659236621 0.8359008676208203 0.6742423742126434 0.8068972164131537 0.886886882990623 1.0 14.368941374350833 -6.8870696464346794 8.400374902009496 0.8160392370117339 0.9906574675181374 0.3033586942263594 0.11446150434000556 0.2978720023456623 20.804569597334595 0.041694323269253625 0.0367814113019967 1.296971263119634e-07 6.8870696464346794 0.17461823050640357 MPLDLS(ph)PLATPIIR ddPTM_PC-9_AZD4547_30min_R2 2 MPLDLSPLATPIIR 14 0 B8ZZU6;E9PBF9;P15336-5;P15336;E9PEK8;H7C2N6;P15336-3;P15336-7;P15336-4;C9JCI8 B8ZZU6 ATF2 Cyclic AMP-dependent transcription factor ATF-2 1 MPLDLS(1)PLATPIIR;MPLDLS(1)PLATPIIR 163.64 1.3858e-05 5295600.0 18895.4 18081.0 24290.0 34884.0 34789.0 33155.0 24495.0 34366.0 26178.0 28529.0 True False 24903.744151264385 23925.329656773818 23967.89872919595 26842.032752427454 29959.147851851303 31081.812608758875 26675.00754689731 29055.524352117685 27561.71563655377 27530.20839355177 0.904597008321137 0.8690573392963382 0.8706036070111914 0.9750028902329159 1.088228153727614 1.1290075310886123 0.9689359108936215 1.0554051729925582 1.0011444607520437 1.0 14.748727910195084 -5.940502940505923 3.650373688686423 1.0437324243835295 0.8807616160631354 0.7178211072456813 0.04449909833427711 0.12115769627834572 3.3019552163759123 0.01346949539157324 0.020431906390568463 1.146824756515148e-06 5.940502940505923 -0.16297080832039412 MPLDLS(ph)PLATPIIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MPLDLSPLATPIIR 14 0 B8ZZU6;E9PBF9;P15336-5;P15336;E9PEK8;H7C2N6;P15336-3;P15336-7;P15336-4;C9JCI8 B8ZZU6 ATF2 Cyclic AMP-dependent transcription factor ATF-2 1 MPLDLS(0.982)PLAT(0.018)PIIR 84.75299999999999 0.0063076 1362700.0 6132.1 4785.3 6381.7 8365.4 8304.5 6572.5 7708.7 6401.1 5757.8 4367.7 True False 7170.143415504302 5260.352959054045 6533.863930732021 7896.713758992731 6677.29283935206 6227.82652977501 6978.476129845044 6233.0779075260725 5841.996932312582 5159.529435305824 1.3896894097434878 1.019541224643143 1.2663681858314149 1.530510457980295 1.2941670210582434 1.207053202789968 1.3525411992210883 1.2080710044745806 1.132273205447137 1.0 12.333023778157946 -8.408189898068331 1.5803539407972351 1.0031742501426404 1.2888080727880848 0.3634564364444274 0.12437305821353649 0.4335782142821293 2.288620980225245 0.12278403142602239 0.03628093263837077 3.90670035442984e-09 8.408189898068331 0.28563382264544446 MPLDLS(ph)PLATPIIR ddPTM_PC-9_Lapatinib_30min_R1 4 MPLDLSPLATPIIR 14 0 B8ZZU6;E9PBF9;P15336-5;P15336;E9PEK8;H7C2N6;P15336-3;P15336-7;P15336-4;C9JCI8 B8ZZU6 ATF2 Cyclic AMP-dependent transcription factor ATF-2 1 MPLDLS(1)PLATPIIR;MPLDLS(0.999)PLAT(0.001)PIIR;MPLDLS(1)PLATPIIR;MPLDLS(1)PLATPIIR 166.9 3.0743e-05 68822500.0 131456.0 128236.0 180395.0 119340.0 199423.0 206867.0 213934.0 200865.0 204143.0 168896.0 True False 129581.41333392187 127939.07742079638 165563.6194448378 128116.66170656937 187693.33122070294 198019.78064052982 225010.4557328986 210197.9211937338 181150.26561890842 198089.4485602266 0.6541560606875246 0.6458651803551169 0.8358023137941154 0.6467616656907251 0.9475180661308023 0.99964830070353 1.1359032869662768 1.0611262877529077 0.9144872022995812 1.0 17.595792510064264 -6.404805543624091 3.254643729587563 1.0307339086773255 0.7013321846580506 0.8117185592940555 0.0744974827362109 0.10931953932436655 2.1745730925052187 0.025146444736447473 0.028625439483984008 3.937263278836271e-07 6.404805543624091 -0.3294017240192749 MPLLELGGETT(ph)PPLSTER ddPTM_PC-9_AZD4547_30min_R2 3 MPLLELGGETTPPLSTER 18 0 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 MPLLELGGET(0.235)T(0.756)PPLS(0.005)T(0.005)ER;MPLLELGGET(0.236)T(0.756)PPLS(0.006)T(0.002)ER;MPLLELGGET(0.138)T(0.843)PPLS(0.014)T(0.005)ER 140.75 0.00060198 24552100.0 22923.0 27094.1 30814.1 41150.0 35128.6 30380.0 24926.1 35017.6 29998.4 30725.6 True False 30212.037171980126 35851.73797099691 30405.484900424733 31663.503261162376 30251.600253774013 28480.333797439147 27144.474611745954 29606.434544396096 31584.05418105259 29649.906096144794 1.0189589496173286 1.2091686852140993 1.025483345607566 1.0679124297557017 1.0202932904973838 0.9605539290777815 0.9154995136822842 0.9985338384678948 1.0652328570160052 1.0 14.855739915186133 -6.038401086154841 1.4172148841481107 0.984950396446317 1.1047022052320201 0.34560558807596964 0.059887268238976256 0.4317902607897904 1.7539453527162436 0.021435200477501214 0.036850702969307064 9.153747190403204e-07 6.038401086154841 0.11975180878570313 MPLLELGGETT(ph)PPLSTER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MPLLELGGETTPPLSTER 18 0 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 MPLLELGGET(0.209)T(0.79)PPLS(0.001)TER;MPLLELGGET(0.077)T(0.923)PPLSTER 123.92 0.00015441 3995200.0 12732.400000000001 17700.4 17248.300000000003 17004.3 18189.1 18661.1 15220.099999999999 15722.6 12837.0 11720.5 True False 14887.743843637085 19457.578734131668 17659.56488654203 16051.604199684409 14625.076426546868 17682.479065010953 13778.341944018399 15309.898409471707 13024.71683978197 13845.333870573057 1.075289623407318 1.4053528008802234 1.2754885546007495 1.1593511828415037 1.0563180753359138 1.2771435655006764 0.9951614076496167 1.1057803699491453 0.9407297044287801 1.0 13.7571122232588 -7.083295266222559 0.5993782420865037 0.9771737532173462 1.2603531938893586 0.42992062250767304 0.10661887287578872 0.7680664041655012 0.577648719758841 0.09221105499283526 0.0785533080965681 8.254765373953454e-08 7.083295266222559 0.2831794406720124 MPLLELGGETT(ph)PPLSTER ddPTM_PC-9_Lapatinib_30min_R1 1 MPLLELGGETTPPLSTER 18 0 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 MPLLELGGET(0.163)T(0.501)PPLS(0.258)T(0.077)ER 113.14 0.00061922 6032800.0 16304.0 14034.0 13159.0 11426.0 13057.0 16440.0 15906.0 12801.0 11442.0 9153.0 True False 16071.501970212583 14001.505135246394 12077.11781520894 12266.306156018636 12289.012931049685 15736.899523511787 16729.534851344277 13395.781192348039 10153.281470398464 10735.083854394126 1.497100738866994 1.3042753391735495 1.1250138311928963 1.1426371998946 1.1447523929698507 1.4659316812947203 1.558398153033195 1.2478506338695086 0.945803647937271 1.0 13.390045840037805 -8.200857521602956 4.891901251763636 0.9718714663344187 1.3092538617960292 0.4638984950282785 0.14617046554120167 0.20086870965463813 9.728534336917233 0.12177896825487813 0.04204998937090971 6.297127379704149e-09 8.200857521602956 0.33738239546161053 MPLLELGGETTPPLS(ph)TERSPEAVGSECPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MPLLELGGETTPPLSTERSPEAVGSECPSR 30 1 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 MPLLELGGET(0.031)T(0.031)PPLS(0.362)T(0.142)ERS(0.314)PEAVGS(0.112)ECPS(0.007)R 47.577 0.027638 24476000.0 4696.9 4166.7 8156.6 8866.4 9786.2 10508.0 11788.0 9029.2 9612.2 9218.9 True False 5491.992401996407 4580.3424392390225 8351.08427807776 8369.644353256637 7868.664360824509 9956.94198172322 10671.355302270611 8792.19306722819 9752.760240504189 10890.213593227749 0.5043052971350066 0.4205925255761173 0.766843019798162 0.7685473091603486 0.7225445390453831 0.9143018083607746 0.9799032141028677 0.8073480829334472 0.8955527049138041 1.0 13.4107446299191 -5.164838504435694 0.5804089758403516 0.9214525195798551 0.23763432681246566 0.7962394442605135 0.08190675107069999 1.1491115531361757 0.4002480509775531 0.04709473490790045 0.49766782491849537 6.841660120964069e-06 5.164838504435694 -0.6838181927673894 MPLLELGGETTPPLSTERS(ph)PEAVGSECPSR ddPTM_PC-9_AZD4547_30min_R2 2 MPLLELGGETTPPLSTERSPEAVGSECPSR 30 1 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 MPLLELGGET(0.004)T(0.004)PPLS(0.283)T(0.091)ERS(0.318)PEAVGS(0.29)ECPS(0.009)R;MPLLELGGET(0.013)T(0.013)PPLS(0.201)T(0.084)ERS(0.646)PEAVGS(0.04)ECPS(0.002)R 48.626000000000005 0.023799 80174000.0 18119.4 17258.3 38222.0 40586.0 43906.0 36043.0 26568.7 37134.0 25830.5 35760.0 True False 23880.992293067076 22836.707970549152 37715.15130618886 31229.52474744926 37810.40977272654 33789.22551221525 28933.26282960813 31395.793554429878 27195.847495989092 34508.05328449688 0.6920411330127357 0.6617790862403935 1.0929376686436498 0.9049923648251543 1.0956981392431453 0.9791692748833047 0.8384495813505284 0.9098106258151277 0.7881014692940423 1.0 15.074645468332445 -5.24312548807092 24.593286992633665 0.9484141903526214 0.6769100256602282 0.5779874265994729 0.09370835445825897 483.27942562644444 648981.23579592 0.024553442455524332 0.06467583541455543 5.713135335104452e-06 5.24312548807092 -0.27150416469239325 MPLLELGGETTPPLSTERS(ph)PEAVGSECPSR ddPTM_PC-9_Lapatinib_30min_R1 2 MPLLELGGETTPPLSTERSPEAVGSECPSR 30 1 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 MPLLELGGET(0.001)T(0.001)PPLS(0.098)T(0.058)ERS(0.744)PEAVGS(0.094)ECPS(0.005)R;MPLLELGGET(0.001)T(0.001)PPLS(0.137)T(0.049)ERS(0.634)PEAVGS(0.155)ECPS(0.023)R 73.212 8.2974e-06 15470700.0 12327.7 14401.5 15762.699999999999 13687.7 16230.9 15713.5 11161.6 8828.2 15263.2 8939.5 True False 12151.904737376688 14368.154211575516 14466.751651781582 14694.339118828668 15276.230373177164 15041.470234957575 11739.493033871757 9238.390400928596 13544.09768737859 10484.680663864992 1.1590152458584373 1.3703950241512601 1.3797989767719516 1.401505643321316 1.4570048304690906 1.4346140542741912 1.11968055205834 0.8811322630710459 1.2917987797241883 1.0 13.355995300910115 -7.358092001432125 4.969635302477168 1.0548209779798732 1.3729140025463238 0.5849101329288524 0.12169791433307768 0.15553700949370516 6.167773457152611 0.05130747492728204 0.03402579862267346 4.384378087773224e-08 7.358092001432125 0.3180930245664506 MPLLELGGETTPPLSTERSPEAVGS(ph)ECPSR ddPTM_PC-9_AZD4547_30min_R2 1 MPLLELGGETTPPLSTERSPEAVGSECPSR 30 1 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 MPLLELGGET(0.012)T(0.012)PPLS(0.071)T(0.014)ERS(0.359)PEAVGS(0.427)ECPS(0.106)R 53.089 0.0023173 3908500.0 3623.1 1283.7 5128.0 8734.9 7370.4 8095.0 4224.6 6642.7 3711.7 5930.7 True False 4775.170434838424 1698.6309208783 5059.999369424324 6721.203757859717 6347.147182364684 7588.818370318299 4600.581215865374 5616.223349060467 3907.892884414265 5723.067998164585 0.8343724793012844 0.2968042527929179 0.8841410535480426 1.1744057138610338 1.1090462640667984 1.3260052777202835 0.8038662509934885 0.9813308789728893 0.6828318107818298 1.0 12.482573032913995 -5.4735639478100095 7.547647013778347 1.019833327061231 0.5689022556273254 0.41666559678441606 0.207912044151774 0.24995069356787183 33.663693439421394 0.0548178399816676 0.11326379545427051 3.3607487996582174e-06 5.4735639478100095 -0.45093107143390554 MPLPS(ph)PTESR ddPTM_PC-9_AZD4547_30min_R2 1 MPLPSPTESR 10 0 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 1 MPLPS(0.929)PT(0.064)ES(0.007)R 89.35600000000001 0.0094013 7805600.0 20439.0 20232.0 28655.0 32554.0 30264.0 25292.0 21694.0 30994.0 28373.0 30694.0 True False 26938.176842389836 26771.598341676217 28275.015977155603 25049.17825428628 26062.365994665783 23710.487241765324 23624.723973153323 26204.589471266216 29872.738855372467 29619.4124025265 0.9094770847004393 0.9038531209819892 0.9546109690799868 0.8457013904890839 0.8799082723343523 0.8005049836755994 0.7976094748975561 0.8847099704459699 1.0085527170290642 1.0 14.854255399907146 -8.235252717590544 5.325307517530767 1.005711855767644 0.8698067660163996 0.5746680669422424 0.04556684725557917 0.13428195802076243 11.59193479078283 0.03921017767940244 0.013093371613659161 5.817645882560977e-09 8.235252717590544 -0.1359050897512445 MPLPS(ph)PTESR ddPTM_PC-9_Lapatinib_30min_R1 2 MPLPSPTESR 10 0 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 1 MPLPS(0.94)PT(0.06)ESR;MPLPS(0.989)PT(0.011)ESR 132.03 0.00016013 26002000.0 36202.0 49724.0 51384.0 45663.0 64280.0 61130.0 64637.0 62148.0 70817.0 53989.0 True False 35685.75284136628 49608.867133033425 47159.405867975984 49021.20934730258 60499.176779342386 58515.61240098997 67983.58758872996 65035.62296242843 62840.843723930026 63320.92671417947 0.5635696552965193 0.7834513755138157 0.7447680935063695 0.7741707503520356 0.9554373241002297 0.9241117500557136 1.073635385906416 1.0270794559907315 0.9924182570413654 1.0 15.95039474930388 -5.945447662263924 0.694148836236528 1.0337700328740123 0.6105505240673448 0.8655638964955288 0.05591817865773565 0.331171669414487 0.3016974569289606 0.03132694144106967 0.08848001831905121 1.1338414714787232e-06 5.945447662263924 -0.4232195088066675 MPLPSPT(ph)ESR ddPTM_PC-9_AZD4547_30min_R2 1 MPLPSPTESR 10 0 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 1 MPLPS(0.325)PT(0.671)ES(0.004)R 122.18 0.0013705 8609500.0 20251.0 16805.0 22718.0 36183.0 23986.0 34528.0 27717.0 28663.0 20954.0 20296.0 True False 26690.396753032754 22236.88761031379 22416.744476322503 27841.568371777365 20655.957928497668 32368.958701710937 30183.759305056243 24233.791960214996 22061.58566156116 19585.4432176216 1.362767053901472 1.1353783196648115 1.144561510671022 1.4215439529460068 1.0546586921205283 1.6527049371334948 1.541132307789646 1.2373369185952934 1.1264276951216352 1.0 14.257494156325704 -8.345436840458625 2.5673344060958403 1.0137877621246663 1.3228509005384548 0.26930007290162417 0.17649319299826793 0.39286516857114784 4.889796574587772 0.17591537318421233 0.04887089803959969 4.51401668010814e-09 8.345436840458625 0.3090631384137885 MPNS(ph)PAPHFAMPPIHEDHLEK ddPTM_PC-9_AZD4547_30min_R2 1 MPNSPAPHFAMPPIHEDHLEK 21 0 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 MPNS(1)PAPHFAMPPIHEDHLEK 71.742 0.00052184 6790300.0 27638.0 32661.0 35419.0 57151.0 57879.0 49151.0 34989.0 38816.0 38748.0 46157.0 True False 36426.30909388765 43218.029529334075 34949.32091763653 43975.719924148056 49843.499914263186 46077.58020006355 38102.95321732559 32817.87910294474 40796.14017439016 44541.05747909737 0.8178141956100193 0.9702964405282883 0.7846540449570121 0.987307495893769 1.1190461730203463 1.0344967723697907 0.8554568610142874 0.7368006275635869 0.9159221285560034 1.0 15.44284819007163 -10.56273838944167 4.056074463370903 1.0000098859563622 0.9162777246461892 0.05021708736532826 0.11224314181980764 173576266.70973417 401196594.171776 26692.854599084352 0.030608627531825222 2.736916895408726e-11 10.56273838944167 -0.08373216131017303 MPNS(ph)PAPHFAMPPIHEDHLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MPNSPAPHFAMPPIHEDHLEK 21 0 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 MPNS(1)PAPHFAMPPIHEDHLEK 53.201 0.0056415 6411800.0 30458.0 21381.0 21049.0 26167.0 37807.0 32955.0 43930.0 44286.0 39818.0 30675.0 True False 35613.93782707883 23503.564377893665 21550.887988777038 24700.947824558614 30398.989749820357 31226.781786038133 39768.63237434235 43123.539424895665 40400.26292174483 36236.13467683363 0.9828293813536193 0.6486222823572816 0.5947347359472887 0.6816661888705902 0.8389136981890881 0.8617580783527096 1.0974854997370098 1.190070072580486 1.1149164578961948 1.0 15.145141450276428 -7.032761134887497 1.7119148195607934 1.124775724897491 0.7211665441292804 0.693868593552881 0.11002296285905677 0.19924366117407769 1.1717940635506563 0.054178935417296625 0.04001119349416038 9.273397267116174e-08 7.032761134887497 -0.4036091807682106 MPQPSSGRES(ph)PRH ddPTM_PC-9_AZD4547_30min_R2 1 MPQPSSGRESPRH 13 2 P56181-2;P56181 P56181-2 NDUFV3 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial 1 MPQPS(0.002)S(0.029)GRES(0.969)PRH 79.82 0.012126000000000001 2378700.0 4197.0 3459.1 4939.4 7477.6 5912.6 6281.4 3864.8 6254.3 5826.0 5619.9 True False 5531.558696976865 4577.186428612704 4873.900328653373 5753.7548477683595 5091.737548905001 5888.623065017588 4208.759712890335 5287.841644516372 6133.9504659852655 5423.14901156443 1.0199901727172276 0.8440089731726385 0.8987214473104412 1.0609619679449964 0.9388894787967801 1.0858309540196243 0.7760730350420932 0.9750500370247017 1.1310680294613165 1.0 12.404915096411399 -8.018810015592324 24.1722755454774 1.061375755068729 0.9447487260756713 0.19952836133656615 0.09404669694905804 789.7040166745805 1014820.4037819352 0.06013329712047917 0.023627831122441312 9.57612892482062e-09 8.018810015592324 -0.11662702899305777 MPRRPRSNS(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 1 MPRRPRSNSSR 11 3 V9GY78 V9GY78 RRBP1 1 MPRRPRS(0.006)NS(0.497)S(0.497)R 60.06399999999999 0.035579 42111000.0 48343.0 46313.0 30849.0 37426.0 52011.0 46069.0 60218.0 44809.0 43637.0 56982.0 True False 47653.61995497955 46205.76509396226 28312.714300583666 40178.43288947609 48951.81523756034 44098.73626208425 63335.793391063096 46890.98972329687 38722.141542018646 66831.26277625762 0.7130438357048209 0.691379500768273 0.42364476031780146 0.6011921849208246 0.73246880582587 0.6598519080766301 0.9476970920496162 0.7016325560132212 0.5794016143560738 1.0 16.02823551370709 -6.569585359383588 1.9289854548562075 0.7754146814658252 0.6032047352063787 0.25766463967787623 0.13750188958706727 0.5192723682601126 3.9237258639624195 0.053094897519354034 0.055731601593663464 2.6941057612463613e-07 6.569585359383588 -0.1722099462594464 MPS(ph)ARPPSPPLSSWER ddPTM_PC-9_AZD4547_30min_R2 1 MPSARPPSPPLSSWER 16 1 O43896 O43896 KIF1C Kinesin-like protein KIF1C 1 MPS(0.864)ARPPS(0.119)PPLS(0.015)S(0.002)WER 49.924 0.045899 36124000.0 46004.0 48214.0 73866.0 103230.0 92525.0 95272.0 62677.0 82319.0 81402.0 76126.0 True False 60632.315057356136 63798.232623842254 72886.4885768129 79431.91838760133 79679.50084775465 89314.62677911876 68255.1315785623 69598.4900524347 85704.7435345233 73460.85191095088 0.8253690704656479 0.8684657333021181 0.9921813684541227 1.0812822928311336 1.084652556770537 1.2158125648663292 0.9291361290133289 0.9474228550575737 1.166672333699784 1.0 16.1646880063647 -5.319675054530315 2.3204532519199548 1.0603256831101084 0.8300790781959508 0.5047271585765414 0.08402154225994006 0.27130222925046255 2.759909227047351 0.024401024859992845 0.07730678513608627 4.789883443510819e-06 5.319675054530315 -0.2302466049141576 MPS(ph)ARPPSPPLSSWER ddPTM_PC-9_Lapatinib_30min_R1 1 MPSARPPSPPLSSWER 16 1 O43896 O43896 KIF1C Kinesin-like protein KIF1C 1 MPS(0.951)ARPPS(0.049)PPLSSWER 101.71 0.0034755000000000003 19142000.0 23802.0 14336.0 20650.0 19243.0 17555.0 22016.0 15598.0 20233.0 17252.0 13220.0 True False 23462.579115247787 14302.805872801211 18952.236711305148 20658.19441276621 16522.449414457926 21074.427001802647 16405.58811839984 21173.099044197956 15308.898088386144 15505.059385457273 1.5132208482383591 0.9224605670466701 1.2223259672956235 1.3323518407251145 1.0656166483280225 1.3591967936329916 1.0580796700325574 1.3655606546116767 0.9873485620277523 1.0 13.920451431133047 -8.289459095166855 23.771822271424234 0.9936739895067314 1.215882346863046 0.23938175368662074 0.16691834113899776 648.2584766302615 549970.206591024 0.14705329428860414 0.03801257704441402 5.1350054022835944e-09 8.289459095166855 0.2222083573563146 MPS(ph)GTEQQTEGTSVTFSPLKSPPQLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MPSGTEQQTEGTSVTFSPLKSPPQLER 27 1 A0A075B6Q3;Q5H9F3-3;H7C4B2;Q5H9F3-2;Q5H9F3 A0A075B6Q3 BCORL1 BCL-6 corepressor-like protein 1 1 MPS(0.7)GT(0.104)EQQT(0.112)EGT(0.033)S(0.033)VT(0.005)FS(0.011)PLKSPPQLER 48.373999999999995 0.039095 6121700.0 8702.7 3340.1 10265.0 16689.0 16989.0 12071.0 12898.0 14773.0 8353.8 13563.0 True False 10175.895223840007 3671.6830540481096 10509.756530229284 15753.969436468018 13660.12740655693 11437.975510218976 11676.208066566533 14385.224403287346 8475.958521163095 16021.86453535107 0.635125531200669 0.22916702646853682 0.6559633872225219 0.9832794055715576 0.8525928662308223 0.7138979040162224 0.7287671195074603 0.8978495837077766 0.5290244779227482 1.0 13.967754429878934 -5.51557990136665 23.213466156775947 0.8057148286801427 0.4347508821912824 0.47848012780980387 0.1591495647988082 98.07958434599173 311933.37523337157 0.04054041915592522 0.0743208917167235 3.0508446840277983e-06 5.51557990136665 -0.3709639464888603 MPS(ph)LEISAPK ddPTM_PC-9_AZD4547_30min_R2 2 MPSLEISAPK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 MPS(1)LEISAPK;MPS(1)LEISAPK 137.4 0.00011719 17783700.0 64533.0 83456.0 94094.0 129418.0 125137.0 105855.0 82686.0 114683.0 91942.0 111317.0 True False 85053.1516302141 110431.51992897055 92846.25208007266 99582.67958816793 107763.887571851 99235.87011612665 90044.8938159933 96961.377503169 96801.86641668685 107419.8257122576 0.7917826254721687 1.028036670109485 0.8643306900234343 0.9270419024409627 1.0032029642322733 0.9238133599466725 0.8382520937726521 0.9026394975066954 0.9011545659735777 1.0 16.712900760284512 -6.453886909346842 0.005647345195199387 1.8308555128506085 3.341222040935609e-05 0.06832283385558213 0.06953561320471267 47955.294945755995 86.52193305123379 13752.627626395693 14295.066665113212 3.516519990870288e-07 6.453886909346842 -1.8308221006301992 MPS(ph)LEISAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 MPSLEISAPK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 MPS(0.996)LEIS(0.004)APK;MPS(1)LEISAPK;MPS(1)LEISAPK 93.62299999999999 0.0058783 18810400.0 151126.0 164875.0 165788.0 197428.0 224120.0 171159.0 171982.0 162840.0 142704.0 131604.0 True False 176708.64692544195 181242.7003790854 169741.0146744915 186366.74923021198 180205.2948588813 162183.12073180085 155690.6199181457 158565.6225432422 144790.7760305557 155462.7634233089 1.1366622015091983 1.1658270854582742 1.0918435446326424 1.198787060813751 1.1591540693780225 1.0432280834362446 1.0014656660528822 1.019958857359846 0.9313534176432043 1.0 17.246209540595444 -6.9188019659492515 2.911122817657561 0.9909900189046111 1.1511986791648987 0.8415896193757936 0.03340564522341792 0.10170338542324263 1.7432866771994806 0.013018357513556924 0.011066520396177707 1.2055855503141782e-07 6.9188019659492515 0.16020866026028757 MPS(ph)LEISAPK ddPTM_PC-9_Lapatinib_30min_R1 3 MPSLEISAPK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 MPS(1)LEISAPK;MPS(0.996)LEIS(0.004)APK;MPS(0.999)LEIS(0.001)APK 134.98 0.00011253 9737200.0 149677.0 116093.0 105966.0 95240.0 112501.0 101020.0 102566.0 102685.0 113536.0 130522.0 True False 147542.57853259996 115824.19379123267 97253.884520589 102244.26731132645 105883.91236547606 96699.61008912165 107876.36562070763 107456.11997002234 100748.38009291724 153082.55379036718 0.9638105380358776 0.7566126310503254 0.6353035150809508 0.6679028065558718 0.6916785077316817 0.6316827600194277 0.7046940552640285 0.7019488328968816 0.6581310384387963 1.0 17.223950348428644 -10.443809569698193 5.25804718661021 1.000000621773524 0.7066210930521198 0.4704389691354085 0.09134918205511894 131017284.47656125 21.043300077787517 986.2692246150349 0.022669153506934034 3.599071133433548e-11 10.443809569698193 -0.29337952872140416 MPS(ph)PFR ddPTM_PC-9_Lapatinib_30min_R1 1 MPSPFR 6 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 MPS(1)PFR 90.37 0.037231 10613000.0 21522.0 21091.0 21495.0 16438.0 17522.0 17932.0 16626.0 15666.0 21511.0 13346.0 True False 21215.092333348577 21042.165085327186 19727.76407309948 17646.905355560517 16491.390409577438 17165.090161533673 17486.812928357205 16393.899551544764 19088.20465912787 15652.838317572821 1.3553511448164155 1.3443034840335621 1.2603314282593656 1.127393319826797 1.053571887410554 1.0966119890386337 1.1171656266790575 1.047343569194092 1.219472422308119 1.0 13.93413666325101 -5.641202749178114 2.2001575000436158 1.092104070308564 1.350870981846924 0.795282887827215 0.053958426760258436 0.12631726437102467 1.2326205792902356 0.015124060719811063 0.032438672149300116 2.2845320269236236e-06 5.641202749178114 0.25876691153835996 MPSARPPS(ph)PPLSSWER ddPTM_PC-9_AZD4547_30min_R2 2 MPSARPPSPPLSSWER 16 1 O43896 O43896 KIF1C Kinesin-like protein KIF1C 1 MPS(0.05)ARPPS(0.693)PPLS(0.033)S(0.225)WER;MPSARPPS(0.973)PPLS(0.013)S(0.013)WER 70.117 0.024475999999999998 18830700.0 39239.0 33226.0 40260.0 61974.0 51137.0 43320.0 43566.0 51200.0 31683.0 38649.0 True False 51716.18577809747 43965.654730156886 39726.12609458333 47686.851788755266 44037.510238872084 40611.19355184543 47443.289601474935 43288.21645895435 33357.69869787353 37295.91027384004 1.386644953786583 1.178833132301777 1.0651603836157844 1.2786080682471934 1.1807597646908947 1.0888913356360894 1.2720775348591622 1.1606692567929469 0.8944063424903498 1.0 15.186729818310502 -1.5228794211161925 0.07641223203643582 0.799015954842458 2.053720507065598 0.3984870890481348 0.10636707251245929 249.75272057998774 1.4032988402944229 3.666915813991816 33.27059643690688 0.029999953314949382 1.5228794211161925 1.2547045522231401 MPSARPPS(ph)PPLSSWER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MPSARPPSPPLSSWER 16 1 O43896 O43896 KIF1C Kinesin-like protein KIF1C 1 MPS(0.016)ARPPS(0.479)PPLS(0.479)S(0.025)WER;MPS(0.034)ARPPS(0.88)PPLS(0.079)S(0.007)WER 77.74 0.022491 28962000.0 29899.0 32950.0 40669.0 39707.0 47743.0 37208.0 40002.0 39378.0 37331.0 27771.0 True False 34960.31016783208 36221.05824103626 41638.70319804141 37482.34552183092 38388.101875993154 35256.746979059535 36212.72097059965 38344.36922443982 37876.895251686605 32805.662464884976 1.0656791401561676 1.104109946866859 1.269253539464758 1.142557189995838 1.1701669465472186 1.0747152878500226 1.103855805666524 1.1688338641380416 1.1545840689006006 1.0 15.00165723417755 -6.743567042292846 24.976917969364244 1.1111660357884408 1.15395672222602 0.11532370909307144 0.06550908548102098 653.8303607584782 913737.8710478389 0.02221188295138341 0.02216520805201452 1.8048161051094753e-07 6.743567042292846 0.04279068643757933 MPSLVVS(ph)GIMER ddPTM_PC-9_AZD4547_30min_R2 1 MPSLVVSGIMER 12 0 A1L020 A1L020 MEX3A RNA-binding protein MEX3A 1 MPS(0.411)LVVS(0.589)GIMER 60.91 0.034675 2621800.0 10715.0 11396.0 6126.1 7496.6 9566.5 6328.9 10150.0 7975.4 7897.8 9320.0 True False 14122.147114154654 15079.534139073849 6044.863911277366 5768.374691315433 8238.356604810018 5933.152882508643 11053.330336844578 6742.985186459851 8315.261584321737 8993.709636787222 1.5702249332567333 1.6766756708926436 0.6721213109384686 0.6413787996580286 0.9160131844942423 0.659700292995907 1.2290068040036373 0.7497445946974796 0.9245641587437502 1.0 13.134700591803409 -5.2562153796203 24.984289749002954 0.8419082487908035 1.6234503952483257 0.7595791141767227 0.17423012002824587 188.74312199897798 902675.1678557082 0.04435526925898676 0.11016848348668236 5.5435072567470615e-06 5.2562153796203 0.7815421464575222 MPSRT(ph)ARYARY(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MPSRTARYARYSPR 14 3 I3L267;Q86WC6 I3L267 PPP1R27 Protein phosphatase 1 regulatory subunit 27 2 MPS(0.001)RT(0.989)ARY(0.3)ARY(0.678)S(0.032)PR 72.705 0.020801 0.0 45394.0 49754.0 54761.0 57609.0 60195.0 55229.0 63361.0 57751.0 57729.0 36921.0 True False 53078.30762763203 54693.24830726913 56066.70992224901 54381.354500897985 48400.221863423096 52332.694014902096 57358.98738608482 56235.097442242455 58573.17741246192 43614.48503352484 1.2169880622649263 1.254015684588009 1.285506635677404 1.2468645327142358 1.1097281516959248 1.1998925121935038 1.31513618335732 1.289367452098004 1.3429753295823368 1.0 15.412519735089788 -7.21989141316273 24.944189346602293 1.2609838152329815 1.2197773525834457 0.0 0.09864765913973847 1936.5448906015758 1162646.7482435426 0.03666236595088351 0.028397859404393638 6.027102631445888e-08 7.21989141316273 -0.04120646264953587 MPSRTGPKMEGS(ph)GGR ddPTM_PC-9_AZD4547_30min_R2 1 MPSRTGPKMEGSGGR 15 2 F2Z3C5;Q05513 F2Z3C5 PRKCZ Protein kinase C zeta type 1 MPSRTGPKMEGS(1)GGR 77.506 0.011588 9091200.0 7062.8 6732.3 9599.4 14371.0 12883.0 11963.0 8006.5 12384.0 9514.5 9373.5 True False 9308.62348463383 8908.384317698037 9472.10568386346 11057.98797973669 11094.417826767096 11214.951718853345 8719.062989354295 10470.337356009579 10017.41704576327 9045.336618071347 1.0291074702556091 0.9848593472906583 1.0471811148453543 1.222507071505149 1.2265345442868278 1.2398600729183922 0.9639290783202914 1.1575398239012216 1.107467579011912 1.0 13.142958477744724 -5.5690266285511845 8.280556940600746 1.1391387400429673 1.0091323810437003 0.25474385600508453 0.08782194063534722 0.31691635527312134 50.95192348427967 0.024539391754502773 0.04275341097220617 2.697574026957916e-06 5.5690266285511845 -0.13000635899926705 MPTFS(ph)TPGAK ddPTM_PC-9_Lapatinib_30min_R1 2 MPTFSTPGAK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 MPT(0.026)FS(0.487)T(0.487)PGAK;MPT(0.107)FS(0.559)T(0.335)PGAK 73.781 0.023829 9376900.0 155927.0 190660.0 206604.0 169609.0 129014.0 141741.0 129590.0 109543.0 131327.0 111004.0 True False 153703.45238649042 190218.53848411507 189617.81663450325 182082.6116590374 121425.65017128305 135679.06784440912 136299.53611126012 114632.76768638217 116535.57032538184 130190.89349646763 1.180600641554555 1.4610740688193842 1.456459907003004 1.3985817807140075 0.9326739137448012 1.0421548251229291 1.0469206597384497 0.8804975878707861 0.8951130697059368 1.0 16.990269013823955 -6.259516955136411 24.97238888065112 0.9680826536729498 1.3862631027474095 0.8330195591186654 0.08941107234324279 66.37174885104504 862171.3998700371 0.027837151916778175 0.034143235447755965 5.501524417856278e-07 6.259516955136411 0.4181804490744597 MPTFST(ph)PGAK ddPTM_PC-9_Lapatinib_30min_R1 1 MPTFSTPGAK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 MPT(0.03)FS(0.212)T(0.758)PGAK 81.771 0.027038999999999997 0.0 108060.0 107660.0 127550.0 106780.0 80239.0 97821.0 72244.0 66708.0 87084.0 67854.0 True False 106519.04458422273 107410.71988461076 117063.33135723817 114632.95740763782 75519.49977594358 93637.42386188838 75984.44082739313 69807.49720952685 77275.68288482598 79582.47349022813 1.3384736602501066 1.3496780782743532 1.470968747554853 1.4404296873445823 0.9489463755511012 1.1766086143751997 0.9547886298950383 0.8771717458379633 0.97101383628538 1.0 16.280163119453547 -6.261295040299961 24.999920620563294 0.9897078203553504 1.4013783958174866 0.8642365097505049 0.07995641454070469 4.872373631424662 843913.9061803499 0.026212703461066453 0.03172583666089337 5.47904616498721e-07 6.261295040299961 0.41167057546213615 MQAS(ph)AHVTRPSKRPS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 MQASAHVTRPSKRPSK 16 3 A0A087WYE2;Q5T4B2-2;Q5T4B2 A0A087WYE2 CERCAM Probable inactive glycosyltransferase 25 family member 3 2 MQAS(1)AHVTRPS(0.003)KRPS(0.997)K 70.99 0.042067 0.0 7808.5 5477.9 6881.7 5590.9 5569.7 7034.3 9119.9 6159.2 6334.8 4911.3 True False 7697.149358096475 5465.216259111169 6315.913190130198 6002.073436695655 5242.101196451513 6733.459386754194 9592.08379798659 6445.378917265066 5621.308115598684 5760.211661104105 1.3362615492190268 0.9487874023822952 1.0964724148555989 1.0419883486616863 0.9100535717895336 1.1689604102956765 1.6652311342580075 1.1189482776800652 0.9758856872494168 1.0 12.491906109665585 -6.989769293974809 24.57913490793132 1.2309525032926891 1.0583475689611683 0.0623503565628275 0.20796462761162507 371.8858105153355 893445.6028795327 0.07444975513659911 0.06558248820773101 1.0238367306541417e-07 6.989769293974809 -0.1726049343315208 MQAS(ph)IEK ddPTM_PC-9_AZD4547_30min_R2 5 MQASIEK 7 0 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 MQAS(1)IEK;MQAS(1)IEK;MQAS(1)IEK;MQAS(1)IEK;MQAS(1)IEK 112.11 0.0092188 491939000.0 3852345.0 3750845.0 3832530.0 4231575.0 4253235.0 4461246.0 3397960.0 4438150.0 3378844.0 3820414.0 True False 5077310.576246197 4963232.294478281 3781708.1480693873 3256050.7609320395 3662746.7364301537 4182283.582372939 3700371.85727925 3752335.896041167 3557442.7957932614 3686662.4687035186 1.3772105852781595 1.3462670739759075 1.025780955043409 0.883197414619052 0.993512904293141 1.1344362598628983 1.0037186448968713 1.0178137890016126 0.964949415899281 1.0 21.813883906282513 -5.261287926231346 4.847740902145366 1.002239092350961 1.3686976673133344 0.8606560743995446 0.0578761431972187 0.061875323773911764 4.408178528690916 0.016299132050034557 0.04050391318816032 5.4791359165987e-06 5.261287926231346 0.36645857496237344 MQAS(ph)IEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MQASIEK 7 0 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 MQAS(1)IEK;MQAS(1)IEK 83.86200000000001 0.020397 45596000.0 196452.0 200390.0 192407.0 194463.0 211665.0 141964.0 178219.0 138018.0 139577.0 123859.0 True False 229707.4434961357 220283.3948686272 196994.71258761117 183567.8685675525 170190.76269991606 134519.157926661 161336.80612617623 134395.17374215857 141618.04957125869 146313.6562326956 1.5699658487845563 1.5055559442673687 1.346386370622254 1.2546188325415657 1.1631912364300883 0.9193889442057496 1.1026777013185154 0.9185415579282498 0.9679072563536444 1.0 17.158704904608513 -5.793543589636448 0.7438425670738498 0.9633327414352226 1.6324873646659774 0.9331738419170491 0.05843458577371612 0.2176954784077346 0.21313258373829472 0.028621805958490426 0.09826456687868733 1.6086309133557557e-06 5.793543589636448 0.6691546232307548 MQAS(ph)IEK ddPTM_PC-9_Lapatinib_30min_R1 3 MQASIEK 7 0 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 MQAS(1)IEK;MQAS(1)IEK;MQAS(1)IEK 101.97 0.011026000000000001 450270000.0 522150.0 508710.0 568010.0 507930.0 427750.0 427010.0 408240.0 355426.0 411940.0 289746.0 True False 514704.0452494164 507532.11325004976 521310.41038200795 545284.8666048095 402590.58598885674 408747.7777089275 429376.6696663389 371940.38950640615 365542.9792794916 339828.21003772295 1.5146007013139997 1.493496120271212 1.5340410094975323 1.6045897618219502 1.1846885399660223 1.2028070820358148 1.2635109651981968 1.0944953318181518 1.0756699075656908 1.0 18.374446093857813 -6.307004079236137 6.276054368738111 1.149275679285066 1.5333430058830777 0.8750863500419949 0.07393154021802564 0.07601507766052437 7.814098904904902 0.023876299256396043 0.027407337744342886 4.931691716995455e-07 6.307004079236137 0.3840673265980117 MQAS(ph)IEKGGSLPK ddPTM_PC-9_AZD4547_30min_R2 1 MQASIEKGGSLPK 13 1 P06748;P06748-2 P06748 NPM1 Nucleophosmin 1 MQAS(1)IEKGGSLPK 62.69 0.022855 21015000.0 31876.0 14074.0 33597.0 144910.0 83436.0 29463.0 23168.0 36585.0 24576.0 51085.0 True False 42011.90493801156 18623.145267929576 33151.48182811018 111503.23833718206 71852.35161019478 27620.67395240122 25229.907117636954 30931.62888966493 25875.037187101607 49296.52969906384 0.8522284467989516 0.3777780176741982 0.672491188132047 2.2618881900585297 1.457553950528069 0.56029651825422 0.5117988481472374 0.6274605753891909 0.5248855719674115 1.0 15.589198469110652 -6.78364525765281 24.667921095531078 0.6132862775861518 1.1209987513393092 0.1911207980962223 0.491054250430354 384.04356213547845 426620.40893186943 0.19415465397479068 0.17136854254224332 1.6457154349412883e-07 6.78364525765281 0.5077124737531573 MQASIEK ddPTM_PC-9_AZD4547_30min_R2 2 MQASIEK 7 0 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 0 ; 116.25 0.0012814 0.0 49051.0 46084.0 49538.0 92932.0 75943.0 64915.0 55285.0 75515.0 56669.0 80260.0 False True 64648.19767581892 60979.75177826251 48881.09375244579 71507.96318508725 65399.62532160006 60855.85478804353 60205.25789876377 63845.89191206915 59664.40764794359 77450.12182924265 0.8347075014078268 0.7873422318522233 0.6311299788554997 0.9232776075258305 0.8444095861564841 0.7857425314606327 0.7773423266073187 0.8243485020311875 0.7703591193760556 1.0 16.24097988792912 -11.06563357767374 2.634487888194616 1.0126430921607965 0.7973403184070841 0.42834327384681536 0.07013538304925607 16736398.898193631 16145375.6808442 1499479.2180246077 0.01775307257387534 8.59738593014417e-12 11.06563357767374 -0.21530277375371243 MQASIEK ddPTM_PC-9_Lapatinib_30min_R1 1 MQASIEK 7 0 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 0 114.5 0.039793 20764000.0 30120.0 32730.0 30552.0 37967.0 38894.0 25740.0 35566.0 27136.0 29239.0 29668.0 False True 29690.483276668467 32654.215695925217 28040.132494130496 40759.21983419914 36606.33138854612 24639.16020287066 37407.43345422547 28396.8376248384 25945.79591968017 34796.074269874916 0.8532710628903712 0.9384453959565192 0.8058418394171134 1.1713740900216114 1.0520247515461378 0.708101724688014 1.0750475230078287 0.8160931432837892 0.7456529641374812 1.0 15.086636928414839 MQCLEMT(ph)TKR ddPTM_PC-9_AZD4547_30min_R2 1 MQCLEMTTKR 10 1 A0A075B6E9 A0A075B6E9 LRRC7 1 MQCLEMT(0.5)T(0.5)KR 61.765 0.028842000000000003 12031000.0 22529.0 21310.0 36964.0 43038.0 37520.0 27968.0 25506.0 38171.0 26300.0 28155.0 True False 29692.753367689224 28198.040760237236 36473.83320815147 33116.25403047162 32310.995642342743 26219.1565387353 27775.984588330815 32272.54903231928 27690.164307485855 27169.30201971505 1.092878769802149 1.0378640106313992 1.342464859115067 1.218884975640568 1.1892464377221281 0.9650287121733827 1.0223297075565478 1.1878313623552466 1.0191709852315252 1.0 14.729689882701159 -6.738524907662302 24.994497889975584 1.0495777063394092 1.1801795507936599 0.35068545044789123 0.09283295318759537 306.394614882441 334206.3191676069 0.03264068597503483 0.03262040672220163 1.825892027490679e-07 6.738524907662302 0.13060184445425072 MQFS(ph)FEGPEK ddPTM_PC-9_Lapatinib_30min_R1 1 MQFSFEGPEK 10 0 A0A0C4DGT3;A0A3B3IU98;Q6DN90-2;A0A2R8Y7T6;A0A3B3IRZ4;Q6DN90;Q6DN90-3;A0A2R8Y695 A0A0C4DGT3;A0A2R8Y7T6 IQSEC1 IQ motif and SEC7 domain-containing protein 1 1 MQFS(1)FEGPEK 66.78399999999999 0.039892000000000004 8608200.0 115110.0 92376.0 119740.0 108720.0 108400.0 87105.0 75802.0 81865.0 119380.0 123270.0 True False 113468.51029141128 92162.10904756468 109895.43940976646 116715.63147928833 102024.1251225998 83379.72220167246 79726.65665796543 85668.74676287593 105934.16727286902 144577.05525304997 0.7848306917913765 0.637460134225693 0.760116736486429 0.8072901420976073 0.7056730056095641 0.576714763319358 0.5514475067874474 0.592547320962734 0.7327176991359716 1.0 17.14147908551417 -8.555060373941311 20.76427501112225 1.0000000028687646 0.6753814966349431 0.5676871645432033 0.0841848817216086 928.2358356204708 598917.7818576134 0.0907965254800646 0.02344356206634972 2.785733879747273e-09 8.555060373941311 -0.3246185062338215 MQGPPAPAPVPGPGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 MQGPPAPAPVPGPGSPR 17 0 B7Z6T1;Q08493-3 B7Z6T1 PDE4C 1 MQGPPAPAPVPGPGS(1)PR 62.104 0.026369999999999998 12786000.0 3509.4 23083.0 12227.0 15200.0 14199.0 16384.0 19039.0 31162.0 8757.0 5222.5 True False 4625.3161999453405 30544.128337332546 12064.861991020125 11695.874837659016 12227.713942580605 15359.505889968497 20733.43411656984 26346.62893152218 9219.877142230178 5039.661864605287 0.9177830426342705 6.060749541918882 2.393982436749268 2.320765787840223 2.426296499862158 3.047725482902309 4.114052623686036 5.227856479134178 1.8294634421772444 1.0 12.299111224216237 -4.541594572938531 24.643266963940047 3.257997309812382 0.1088309976015678 0.16768509278051236 1.4821849383269565 218572723.68849838 17829608860.257946 0.35857309746808036 10656676690.206572 2.8734617940073334e-05 4.541594572938531 -3.1491663122108142 MQGQS(ph)PPAPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MQGQSPPAPTR 11 0 Q14008-2;Q14008;Q14008-3 Q14008-2 CKAP5 Cytoskeleton-associated protein 5 1 MQGQS(1)PPAPTR 85.536 0.010048 4840100.0 35853.0 34931.0 41468.0 39907.0 51477.0 39768.0 38927.0 34644.0 33125.0 26388.0 True False 41922.20477097175 38398.71882906336 42456.754388265734 37671.14017023964 41390.45138073646 37682.496072437076 35239.55275292568 33734.63170835219 33609.39045865685 31171.93551270695 1.3448701237650948 1.231836207713521 1.3620185493762051 1.2084953837686259 1.3278114015045368 1.2088596826807934 1.1304897233141202 1.0822116481859327 1.0781938915841878 1.0 14.927960116414923 -7.414208421718113 0.924092004675696 1.0247421084115091 1.299582119812877 0.8329443697473657 0.04805185117666734 0.21636717697605853 0.347703156294336 0.036384014473620156 0.018725783380902004 3.8529340761551345e-08 7.414208421718113 0.2748400114013678 MQGQS(ph)PPAPTR ddPTM_PC-9_Lapatinib_30min_R1 1 MQGQSPPAPTR 11 0 Q14008-2;Q14008;Q14008-3 Q14008-2 CKAP5 Cytoskeleton-associated protein 5 1 MQGQS(0.998)PPAPT(0.002)R 69.314 0.030842 2300100.0 27086.0 21766.0 24794.0 20789.0 21207.0 21981.0 19144.0 17389.0 24183.0 16520.0 True False 26699.74867303594 21715.60216429906 22755.533027607737 22317.892410071006 19959.645954566182 21040.923870213668 20135.182647688605 18196.956421665494 21459.255881720484 19375.45998848367 1.378018828399721 1.1207786642075241 1.1744512409580523 1.1518638743718213 1.0301508179124386 1.0859573854101998 1.0392105611766893 0.9391754535108507 1.1075482024414065 1.0 14.241942941044801 -1.5228787452907158 0.4005338648074425 1.0162885772540164 6.221177023292057 0.7365937810253445 0.058647366761108564 37.10693985494601 0.4917977623780636 0.041142670838949125 152.4707466645847 0.0299999999992831 1.5228787452907158 5.204888446038041 MQHLIAR ddPTM_PC-9_AZD4547_30min_R2 5 MQHLIAR 7 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ;;;; 143.02 0.0016954000000000001 54401900.0 215353.0 155816.0 266710.0 326392.0 264745.0 247870.0 261488.0 353755.0 224288.0 273240.0 False True 283830.7743793327 206180.47485204748 263173.2511347821 251147.36710613163 227989.72658134368 232370.6497159725 284759.92543062265 299090.2932311988 236143.4057869728 263673.9507677834 1.076446018094906 0.781952385708476 0.9981010652302083 0.9524921456018843 0.8646653411058165 0.8812802669332339 1.0799698817476648 1.1343187006539242 0.8955886810181843 1.0 18.008395524006907 -7.260970851646927 24.99990646437079 1.0386625425557454 0.9210010265299307 0.21536698146072908 0.09381180582161104 57.76431145598552 3082315.5529428707 0.03598382889010808 0.0261274851453551 5.483137646213813e-08 7.260970851646927 -0.11766151602581476 MQHLIAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 MQHLIAR 7 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ;;; 118.69 0.00025121 50829900.0 237658.0 284324.0 292994.0 305371.0 357738.0 292362.0 308347.0 300792.0 271400.0 227498.0 False True 277888.80544053804 312549.8076881461 299980.08814593323 288262.0528961404 287641.80694372026 277030.022046114 279138.1399210415 292896.52871546726 275368.71156164445 268741.58652682236 1.0340372289675483 1.1630124378124536 1.116239924095235 1.0726365674237386 1.0703286032547534 1.030841655831575 1.038686060942717 1.0898816684861465 1.0246598418967088 1.0 18.035860063497864 -6.166469969837205 1.8403620619689152 1.0436496217273579 1.109017746717876 0.36171174130721206 0.037129725934103276 0.3782338221260633 2.5289778687483415 0.012366207165422017 0.017545528132863645 6.816007037446704e-07 6.166469969837205 0.06536812499051803 MQHLIAR ddPTM_PC-9_Lapatinib_30min_R1 5 MQHLIAR 7 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ;;;; 123.99 0.0039086 61191000.0 256636.0 250861.0 267520.0 234772.0 225860.0 266234.0 225627.0 218268.0 254353.0 209704.0 False True 252976.3235787215 250280.14676735335 245525.5382570632 252037.91605643378 212575.35885784493 254847.79244176653 237308.8620586104 228409.52810650904 225705.0866841687 245951.0569869837 1.0285636771713877 1.0176014278344767 0.9982699048537002 1.0247482533477066 0.8642994320170574 1.0361727880488583 0.9648621354417246 0.9286787822936536 0.9176829302917513 1.0 17.90801172956556 MQHNLEQQIQAR ddPTM_PC-9_Lapatinib_30min_R1 1 MQHNLEQQIQAR 12 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 72.73100000000001 0.022083000000000002 0.0 10451.0 8134.4 7209.1 5963.0 5285.0 7392.4 7065.1 6451.8 9021.9 5794.8 False True 10301.966823521323 8115.565296576048 6616.395625930747 6401.538911984872 4974.14669070978 7076.2442845260675 7430.896308200206 6751.574181453881 8005.758617181245 6796.423458914354 1.5157923701780254 1.1940935325228264 0.9735113866768442 0.9418981837555248 0.7318770998863481 1.0411717762001267 1.093353931390732 0.993401047222617 1.177936993711111 1.0 12.730560028744442 -4.857160339499585 2.2356109010589145 0.9878317722201186 1.6027464335796782 0.6840861352237045 0.10925350508773667 0.31357090788734854 2.1212659788177795 0.031218798033938025 0.3648551163404442 1.389439561894145e-05 4.857160339499585 0.6149146613595595 MQLEEQSSES(ph)RQK ddPTM_PC-9_AZD4547_30min_R2 1 MQLEEQSSESRQK 13 1 A0AVK6 A0AVK6 E2F8 Transcription factor E2F8 1 MQLEEQS(0.007)S(0.007)ES(0.986)RQK 74.16199999999999 0.042959 3319000.0 6904.5 7412.7 7950.3 9360.8 8819.8 11342.0 9976.4 11234.0 13244.0 9306.5 True False 9099.987377478374 9808.710311750852 7844.873827366262 7202.812182918325 7595.3230108298085 10632.782947022875 10864.280273152332 9498.04343163854 13944.050801838128 8980.682267678138 1.0132846376527116 1.092201017627895 0.8735275999686907 0.802033962257139 0.8457400879402786 1.1839616000324074 1.2097388538344513 1.057608224914315 1.5526716552508897 1.0 13.132609336177037 -6.8007638118765 8.803658573840613 1.2056704464391224 0.9249882877270962 0.4363351866572921 0.1564912844661125 0.282227628692243 58.125300880353606 0.0550508167117477 0.048846974769884165 1.582108224228465e-07 6.8007638118765 -0.2806821587120262 MQNGFGSPEPSLPGTPHS(ph)PAPPSGGTWK ddPTM_PC-9_AZD4547_30min_R2 1 MQNGFGSPEPSLPGTPHSPAPPSGGTWK 28 0 Q8N1G0;Q8N1G0-2;F8WCX2 Q8N1G0 ZNF687 Zinc finger protein 687 1 MQNGFGSPEPS(0.001)LPGT(0.12)PHS(0.839)PAPPS(0.014)GGT(0.026)WK 58.928999999999995 0.0011555 4416800.0 9437.3 8154.9 12766.0 20847.0 18463.0 11652.0 12401.0 15609.0 10731.0 15844.0 True False 12438.165091965626 10790.811947238803 12596.714498843778 16041.0462329393 15899.731144578203 10923.39859801714 13504.664976079763 13196.987709137074 11298.218752229299 15289.306382538261 0.8135205601067103 0.7057751134847335 0.8238905143028815 1.0491676882909216 1.0399249479843704 0.7144469686664547 0.8832751884351852 0.8631514981091098 0.7389621523402045 1.0 13.900235338166384 -5.524719103245048 24.995771488249122 0.893870851551226 0.7609440563374246 0.2083763971152569 0.10943755540690946 91.15504691142095 1238063.992360437 0.031063019163911906 0.05428451491347268 2.987314155183763e-06 5.524719103245048 -0.13292679521380146 MQNGFGSPEPSLPGTPHS(ph)PAPPSGGTWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MQNGFGSPEPSLPGTPHSPAPPSGGTWK 28 0 Q8N1G0;Q8N1G0-2;F8WCX2 Q8N1G0 ZNF687 Zinc finger protein 687 1 MQNGFGSPEPS(0.002)LPGT(0.115)PHS(0.872)PAPPS(0.01)GGT(0.001)WK 62.831 0.00052433 7716200.0 13140.0 13838.0 14073.0 18903.0 25311.0 18060.0 16679.0 18152.0 15264.0 13052.0 True False 15364.342473170123 15211.745187844 14408.553692149706 17843.926194352865 20351.491246533802 17112.901807187034 15099.044374497067 17675.529233633777 15487.207123349064 15418.224280424854 0.9965053169369744 0.9866081146035084 0.9345144700251223 1.157326931416331 1.3199633677901725 1.1099139236749695 0.9792985300951277 1.1464049888076167 1.0044741107451518 1.0 13.912348998930662 -5.760170306695961 24.99989765937776 1.112821936165693 0.973949168277517 0.2770755877122941 0.0951552601052994 44.34370712351182 873496.7649293743 0.02793806681004102 0.045159933808408464 1.7371194912980494e-06 5.760170306695961 -0.13887276788817604 MQNGFGSPEPSLPGTPHS(ph)PAPPSGGTWK ddPTM_PC-9_Lapatinib_30min_R1 1 MQNGFGSPEPSLPGTPHSPAPPSGGTWK 28 0 Q8N1G0;Q8N1G0-2;F8WCX2 Q8N1G0 ZNF687 Zinc finger protein 687 1 MQNGFGSPEPSLPGT(0.173)PHS(0.817)PAPPS(0.007)GGT(0.003)WK 87.792 1.8406e-07 7065500.0 38290.0 28236.0 34201.0 26845.0 35301.0 38370.0 28823.0 31554.0 39615.0 26163.0 True False 37743.977578473976 28170.621276814683 31389.12579967784 28819.27085229481 33224.6645844363 36729.00454483864 30315.313907977852 33020.11403354037 35153.14153555628 30685.239689993854 1.2300369154614068 0.9180512051206443 1.0229389151525357 0.9391900191574023 1.082757212265496 1.1969600014829147 0.9879445040757941 1.0760911228699932 1.1456042674165379 1.0 14.905257232316544 -6.474907565973331 24.918166212079218 1.0868640861686178 1.018349250698802 0.06464553353817792 0.0970446514267597 911.6110396202828 473527.70678480703 0.02920091885352225 0.033109725313432224 3.3503673985543016e-07 6.474907565973331 -0.06851483546981574 MQNNSS(ph)PSISPNTSFTSDGSPSPLGGIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MQNNSSPSISPNTSFTSDGSPSPLGGIK 28 0 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 MQNNS(0.08)S(0.26)PS(0.26)IS(0.26)PNT(0.08)S(0.057)FT(0.003)S(0.001)DGSPSPLGGIK 58.191 0.0015821 7306200.0 15003.0 16830.0 23662.0 19279.0 21429.0 19158.0 19133.0 13771.0 15631.0 14655.0 True False 17542.711577242888 18500.77117440486 24226.19181863471 18198.860133361326 17230.14127936362 18153.320754268494 17320.58372907564 13409.525841580597 15859.573804053292 17311.835491083835 1.0133363147008856 1.0686776213841316 1.3994005333005848 1.051238047099878 0.99528101963756 1.0486075126821792 1.0005053327820905 0.7745871804573781 0.91611162849956 1.0 14.079471074415702 -6.8651616618311495 1.0836383072409137 0.8963097678241704 1.1425080227899416 0.37451476284219476 0.11733396390989195 0.5206206048871864 1.2880763396576893 0.07027556086335703 0.057378605966533755 1.3640752785234227e-07 6.8651616618311495 0.2461982549657712 MQNNSSPSIS(ph)PNTSFTSDGSPSPLGGIKR ddPTM_PC-9_Lapatinib_30min_R1 1 MQNNSSPSISPNTSFTSDGSPSPLGGIKR 29 1 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 MQNNS(0.005)S(0.04)PS(0.298)IS(0.512)PNT(0.129)S(0.013)FT(0.002)SDGSPSPLGGIKR 90.26799999999999 1.0747e-08 8760700.0 40201.0 12869.0 18074.0 11387.0 11237.0 13443.0 8155.4 7894.1 17323.0 11551.0 True False 39627.726368039504 12839.202621169008 16588.025487657593 12224.437965918456 10576.061752792015 12868.07422716357 8577.646707321326 8260.8887048289 15371.901320722991 13547.57495925998 2.9250789523001184 0.9477122407352477 1.2244276586430265 0.9023340341485145 0.7806608772858725 0.9498433679725122 0.6331499720884268 0.6097688132135008 1.134660732046074 1.0 13.725747009183335 -4.760408500519727 6.151540220505156 0.8908978976480589 2.9956299836181097 0.9140582140181598 0.18544438534501986 0.03607661980235664 5.568295557331816 0.04882828911586678 0.31919403045699496 1.736167009276814e-05 4.760408500519727 2.104732085970051 MQNNSSPSISPNT(ph)SFTSDGSPSPLGGIKR ddPTM_PC-9_AZD4547_30min_R2 1 MQNNSSPSISPNTSFTSDGSPSPLGGIKR 29 1 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 MQNNS(0.005)S(0.012)PS(0.13)IS(0.054)PNT(0.598)S(0.143)FT(0.054)S(0.005)DGSPSPLGGIKR 98.37700000000001 8.8755e-11 9049300.0 16603.0 10121.0 22230.0 44387.0 31388.0 25473.0 17578.0 23048.0 13966.0 28707.0 True False 21882.408636146498 13392.415323057772 21935.21567517602 34154.262922313865 27030.31799631807 23880.169283152325 19142.40794690187 19486.461190351158 14704.214247845914 27701.976667730767 0.7899222823920967 0.48344619893706753 0.7918285376627192 1.2329179008405988 0.9757541247157611 0.8620384591894356 0.6910123481982535 0.7034321566319985 0.5308001816698672 1.0 14.757701302646586 -9.995270703681026 8.253926643160941 1.0000056906238006 0.7918790087301174 0.09057704416974066 0.2036029035716797 0.0 0.0 0.21786881282036988 0.052840948693312254 1.010949114785523e-10 9.995270703681026 -0.20812668189368322 MQNNSSPSISPNT(ph)SFTSDGSPSPLGGIKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MQNNSSPSISPNTSFTSDGSPSPLGGIKR 29 1 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 MQNNS(0.005)S(0.012)PS(0.163)IS(0.128)PNT(0.57)S(0.068)FT(0.007)S(0.001)DGS(0.007)PS(0.039)PLGGIKR;MQNNS(0.003)S(0.007)PS(0.159)IS(0.037)PNT(0.383)S(0.383)FT(0.006)S(0.002)DGS(0.004)PS(0.017)PLGGIKR 63.701 0.00015798 15644800.0 57958.0 47149.0 59900.0 73082.0 90484.0 89791.0 82628.0 86472.0 78649.0 68353.0 True False 67769.1446773208 51829.64112311438 61328.24317201505 68987.45247504085 72754.30974482904 85082.20189197848 74800.87766508452 84202.2016246574 79799.0928357101 80744.85781794957 0.839299820554712 0.6418940168297956 0.7595312547368409 0.8543881844535857 0.9010395424667621 1.0537166599984367 0.9263856508823562 1.0428181298492456 0.9882869942706217 1.0 16.301082765216535 -6.163516223297917 1.5101222815020041 1.0001787027974631 0.7326806580695479 0.779423851732223 0.05840129916040964 0.16689193664526836 0.7610866703988826 0.0201854169060691 0.030133446986727375 6.862522426205776e-07 6.163516223297917 -0.2674980447279153 MQNNSSPSISPNT(ph)SFTSDGSPSPLGGIKR ddPTM_PC-9_Lapatinib_30min_R1 2 MQNNSSPSISPNTSFTSDGSPSPLGGIKR 29 1 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 MQNNSSPS(0.005)IS(0.013)PNT(0.635)S(0.345)FT(0.002)S(0.001)DGSPSPLGGIKR;MQNNS(0.001)S(0.003)PS(0.166)IS(0.279)PNT(0.547)S(0.005)FTSDGSPSPLGGIKR 132.33 1.0899e-11 12679100.0 64304.0 16612.2 28198.0 23273.0 18090.7 25562.0 16818.2 13799.4 23381.0 17771.3 True False 63387.01316809065 16573.735471550528 25879.66928742772 24984.57405645211 17026.640593684653 24468.77284793237 17688.964103915405 14440.570501186434 20747.58556715489 20843.04552623122 3.041158888623898 0.7951686067514598 1.241645289065739 1.1987007380955306 0.8168979227270997 1.1739538167365287 0.848674637382221 0.6928243995347418 0.9954200570662193 1.0 14.347278475043645 -4.758371630908813 24.99996600967789 0.9769547034445506 3.041161703627046 0.9243650670560228 0.1774158848359629 21.728021898512164 177037.2428632848 0.045683986648332 0.3146489367363114 1.7443288713201925e-05 4.758371630908813 2.0642070001824955 MQNNSSPSISPNTSFTSDGSPS(ph)PLGGIKR ddPTM_PC-9_AZD4547_30min_R2 1 MQNNSSPSISPNTSFTSDGSPSPLGGIKR 29 1 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 MQNNSS(0.001)PS(0.007)IS(0.002)PNT(0.019)S(0.019)FT(0.005)S(0.005)DGS(0.215)PS(0.726)PLGGIKR 47.59 0.0077631 10296000.0 11397.0 12304.0 22627.0 33729.0 30029.0 19514.0 13638.0 18894.0 18178.0 19898.0 True False 15021.008927673414 16281.027382166081 22326.95119578085 25953.300157855334 25859.991688270526 18293.786495168784 14851.755579693234 15974.366440927404 19138.851968877472 19201.377076479832 0.7822881071416988 0.8479093617774452 1.1627786437843357 1.351637440089965 1.3467779725000542 0.9527330473384238 0.7734734608115925 0.8319385832224887 0.9967437175285231 1.0 14.228922160817024 -6.9860783562671545 24.811864538246425 0.8831865565733226 1.106800581558305 0.20902085526009506 0.1828126680969811 347.31715895445643 619003.6726254827 0.07291129651209749 0.06427154078534651 1.0325750897195086e-07 6.9860783562671545 0.2236140249849825 MQNNSSPSISPNTSFTSDGSPS(ph)PLGGIKR ddPTM_PC-9_Lapatinib_30min_R1 1 MQNNSSPSISPNTSFTSDGSPSPLGGIKR 29 1 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 MQNNSSPS(0.002)IS(0.004)PNT(0.028)S(0.028)FT(0.048)S(0.118)DGS(0.246)PS(0.527)PLGGIKR 47.191 0.033482 0.0 15862.0 9159.0 14349.0 10957.0 10096.0 11556.0 8056.5 9322.7 13415.0 8647.6 True False 15635.804971265461 9137.792898227277 13169.28060874178 11762.814331480507 9502.173129499704 11061.776818351711 8473.626149242746 9755.866676189602 11904.061433787389 10142.326137797305 1.5416389454284716 0.9009563263967184 1.2984477554575922 1.1597748062591031 0.93688301878679 1.0906548131131277 0.8354716693307829 0.9618963681154475 1.1737013059977082 1.0 13.308100951278993 -4.751289321211596 24.924737676947185 1.0423902085632277 1.5416400072318905 0.5557817781740576 0.1345895823937733 321.9873432413317 790624.5646568035 0.034346778016973986 0.45907760592511027 1.773007933048345e-05 4.751289321211596 0.4992497986686628 MQPDCS(ph)NPLTLDECAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MQPDCSNPLTLDECAR 16 0 Q9UBB9 Q9UBB9 TFIP11 Tuftelin-interacting protein 11 1 MQPDCS(0.978)NPLT(0.022)LDECAR 95.9 0.014497999999999999 0.0 4132.5 4348.3 5102.6 6055.7 6533.4 6623.3 5338.8 5615.3 4080.8 4872.3 True False 4832.050629404531 4779.970487086435 5224.2653357182635 5716.418761844297 5253.227170404324 6275.96248834672 4833.070214435217 5467.904324902147 4140.473979884886 5755.6094208944205 0.8395376190508825 0.8304890303594695 0.9076823935885513 0.9931908758596698 0.912714325495001 1.090407987999199 0.8397147653713026 0.9500130959290208 0.7193806384522626 1.0 12.49075297791168 -5.341374249462675 4.278994870025723 0.9307247936306462 0.8346195874864276 0.13457462624998429 0.09382293196650919 0.41583330889844244 14.001840032131858 0.02452410857399309 0.05551859706481168 4.556440994140913e-06 5.341374249462675 -0.09610520614421858 MQQHEQALADCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MQQHEQALADCR 12 0 Q9UNE7;Q9UNE7-2 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 0 69.229 0.028192000000000002 0.0 4288.4 4918.7 7293.8 7066.8 8279.5 6587.1 6391.1 4843.2 7492.4 4682.6 False True 5014.341420239175 5406.996029444156 7467.711853890538 6670.870106874724 6657.1914098880525 6241.660880073186 5785.688740442964 4716.071131794574 7601.962175771783 5531.5183125587955 0.9065036282813312 0.9774885888324869 1.3500293105666479 1.2059745136754112 1.2035016488643853 1.1283811292646502 1.0459494868356665 0.8525816720315605 1.3742993778963433 1.0 12.433459815998804 -7.220092835205106 6.342862147656452 1.0559358488577937 1.1391238873503513 0.02629237112544225 0.16713698864567597 0.7687092117546803 87.1061749692809 0.0666044047528268 0.050703954548785166 6.024307961247753e-08 7.220092835205106 0.08318803849255763 MQQNIQELEEQLEEEESAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MQQNIQELEEQLEEEESAR 19 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 162.29 1.3730000000000004e-20 0.0 2689.8 2413.4 2986.8 2182.0 3044.7 3375.2 2657.2 1854.1 2742.4 2102.3 False True 3145.1300140283865 2652.986402395051 3058.0166395020783 2059.749614139446 2448.112891561827 3198.198570299982 2405.4907795379577 1805.431839581335 2782.502411888923 2483.430348202358 1.2664458321953755 1.068274938459791 1.2313679913413467 0.8293969732754554 0.9857787609521259 1.2878148858151033 0.9686161648460094 0.7269911317980812 1.1204269988498166 1.0 11.278118569302274 -1.5228787455476418 0.4541462056034836 0.9782853677145852 7.329031923265719 0.20514357190276722 0.15641990948217135 149.57498481941644 1.784952229125699 0.09980755635338671 883.1537937033444 0.029999999981535276 1.5228787455476418 6.350746555551133 MQQNIQELEEQLEEEESAR ddPTM_PC-9_Lapatinib_30min_R1 2 MQQNIQELEEQLEEEESAR 19 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 130.95 4.2894e-06 0.0 2905.7 816.74 2463.08 2726.17 1612.2200000000003 2897.3 2063.0 2124.6 743.29 1201.8 False True 2864.2641851598805 814.8488887103558 2260.575070163753 2926.6616360365233 1517.3923893464755 2773.3892329361756 2169.8120456634747 2223.3166722336273 659.5728530093049 1409.5295287021595 2.0320710753730604 0.5780999064706628 1.6037798599687396 2.0763393575239824 1.0765240163103444 1.9675992424861122 1.5393874349417525 1.577346644366345 0.46793830109867524 1.0 10.460997986384495 -10.120594006883177 7.084730379338291 0.999962671761031 1.4463490896925448 0.055065825303625804 0.539460429132652 3.6916760996410985e-10 0.0 0.5014636723804732 0.12162280521381298 7.57540738722013e-11 10.120594006883177 0.4463864179315138 MQQQLDEYQELLDIK ddPTM_PC-9_Lapatinib_30min_R1 2 MQQQLDEYQELLDIK 15 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ; 220.4 4.5981e-77 0.0 33614.0 30658.0 43027.0 37999.0 38292.0 33042.0 37679.0 32307.0 38584.0 36159.0 False True 33134.658195947355 30587.013284621917 39489.48614902309 40793.57322094801 36039.73984496855 31628.870684664034 39629.834255237096 33808.101162502026 34238.26361246758 42409.03497116107 0.7813112988418515 0.7212381348790807 0.9311573860588122 0.9619076040916376 0.8498127785618381 0.7458050084415326 0.9344667777087151 0.7971910038861333 0.8073341832878356 1.0 15.372084033949005 -11.903709041546506 2.2253530087262763 2.1320366219217806 0.8391838584168324 0.28035243809312715 0.07840274051697584 8188202.266170323 1126883.5533459315 46417753.890600055 0.020557532965652787 1.2482194870596511e-12 11.903709041546506 -1.292852763504948 MQS(ph)LQLDCVAVPSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MQSLQLDCVAVPSSR 15 0 Q13546-2;Q13546 Q13546-2 RIPK1 Receptor-interacting serine/threonine-protein kinase 1 1 MQS(1)LQLDCVAVPSSR;MQS(1)LQLDCVAVPSSR 163.0 0.00029093 54825000.0 112727.0 85046.0 90200.0 106554.0 129228.0 104970.0 116481.0 136356.0 94623.0 88549.0 True False 131809.45464026264 93488.80483056676 92350.7100854048 100584.12483272902 103906.70107095983 99465.18841087619 105447.07643058921 132776.7994811241 96006.68236587131 104602.23274650166 1.260101731859743 0.8937553470501176 0.8828751324000147 0.9615867863594239 0.9933506995283033 0.95088972576642 1.0080767270631306 1.2693495730908737 0.9178263201947015 1.0 16.674554120839325 -7.540109211793545 24.970906461606415 1.0838953811570922 0.9799254904820959 0.04794577889769258 0.12872957589070813 528.8265047367437 766381.890792034 0.0582393498105993 0.03363323730600961 2.8833063484980296e-08 7.540109211793545 -0.10396989067499629 MQS(ph)LQLDCVAVPSSR ddPTM_PC-9_Lapatinib_30min_R1 1 MQSLQLDCVAVPSSR 15 0 Q13546-2;Q13546 Q13546-2 RIPK1 Receptor-interacting serine/threonine-protein kinase 1 1 MQS(1)LQLDCVAVPSSR 106.28 0.00084521 31646000.0 83833.0 69101.0 88579.0 85037.0 125860.0 97268.0 110070.0 89554.0 109830.0 100530.0 True False 82637.52604691053 68941.00088005263 81296.37654482803 91290.90465511623 118457.1622502805 93108.07438278255 115768.88602335368 93715.00577295022 97459.78883882744 117906.47655219531 0.7008735097798314 0.5847091940664816 0.689498820778004 0.7742653951218974 1.0046705296790157 0.7896773536572022 0.9818704570660683 0.794824919829269 0.8265855421070407 1.0 16.847283441550985 -5.893747972683105 2.901287088578428 0.8883719161959492 0.6465601612239172 0.6361789168963323 0.08152826842013107 0.16022763018999586 2.7148003319383496 0.02316040200820913 0.03710845379421874 1.277179759531315e-06 5.893747972683105 -0.241811754972032 MQSLS(ph)LNK ddPTM_PC-9_AZD4547_30min_R2 1 MQSLSLNK 8 0 Q13442 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 1 MQS(0.069)LS(0.931)LNK 78.488 0.022056 7271400.0 44045.0 45775.0 50835.0 61102.0 58250.0 47350.0 43662.0 44921.0 42477.0 47125.0 True False 58050.39380708744 60570.873571086835 50160.89468500109 47015.87791648956 50162.992968189326 44389.19701477103 47547.83341549828 37979.49163188841 44722.24750148579 45475.16809373363 1.2765295047933347 1.3319549132009334 1.1030392363060477 1.0338802446992656 1.1030853776019724 0.9761194708126381 1.0455779584473985 0.835169900935933 0.9834432587319762 1.0 15.472791350192516 -5.234625282372865 0.5957491978833457 0.9512071544091417 1.4629084482413657 0.762520937133285 0.067472086789054 1.0733880622889327 0.4180102825037053 0.037493863019673127 0.3514150312105491 5.826056843542816e-06 5.234625282372865 0.511701293832224 MQSLS(ph)LNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MQSLSLNK 8 0 Q13442 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 1 MQS(0.011)LS(0.989)LNK 75.229 0.023483 13945000.0 139110.0 149510.0 119040.0 128360.0 188060.0 188180.0 161550.0 184620.0 146870.0 130880.0 True False 162658.57545225965 164352.36472283222 121878.36506171376 121168.40534873471 151210.99300000578 178311.50952804307 146246.81447928547 179773.92062105905 149017.69589925825 154607.50795449023 1.0520742336791258 1.0630296477659447 0.7883081919772582 0.7837161788055045 0.9780313711835764 1.1533172734439927 0.9459231082253406 1.1627761355158557 0.9638451448497742 1.0 17.23825085466791 -6.526031119257679 24.917478038560102 1.0509796176484334 0.9171543808864459 0.22209752023572704 0.10866909380103879 138.31078436601138 1093240.5077039916 0.03732980033985606 0.03751954359555527 2.978303012258585e-07 6.526031119257679 -0.13382523676198754 MQTEAQHER ddPTM_PC-9_AZD4547_30min_R2 2 MQTEAQHER 9 0 Q9H2K8;F5GWV8;G3V1Q8 Q9H2K8 TAOK3 Serine/threonine-protein kinase TAO3 0 ; 115.91 0.0013232 1371060.0 2848.07 3539.7 3197.3599999999997 4940.9 3560.8999999999996 4924.5 4400.1 2153.02 3181.2599999999998 4988.0 False True 3753.697016463877 4683.838802393793 3154.9609172820888 3801.8518411440427 3066.5305006081626 4616.570236520379 4791.700375876826 1820.3202304776928 3349.414908928989 4813.371638229041 0.7798477446975101 0.9730889601778377 0.6554575782648018 0.7898521300430561 0.6370857542461473 0.9591136075707067 0.9954976960058316 0.37817986378201907 0.6958562855041298 1.0 12.232832102091436 -7.737443305526742 24.99871737334024 0.6527629087095085 0.8224779446885085 0.09258022717701564 0.18282872485660115 416.2275198248439 433619.71528949233 0.08424910314654357 0.0486090886450897 1.830445044056184e-08 7.737443305526742 0.16971503597900006 MQTEAQHER ddPTM_PC-9_Lapatinib_30min_R1 2 MQTEAQHER 9 0 Q9H2K8;F5GWV8;G3V1Q8 Q9H2K8 TAOK3 Serine/threonine-protein kinase TAO3 0 ; 101.3 0.0015396 0.0 1098.62 0.0 0.0 0.0 360.48 504.39 1093.4299999999998 662.46 0.0 0.0 False True 1082.9534773377661 0.0 0.0 0.0 339.27727513094806 482.81841549051774 1150.0424552059208 693.2403100291293 0.0 0.0 0.0 MQY(ph)S(ph)MEY(ph)FQFMK ddPTM_PC-9_AZD4547_30min_R2 1 MQYSMEYFQFMK 12 0 Q93008;Q93008-3 Q93008 USP9X Probable ubiquitin carboxyl-terminal hydrolase FAF-X 3 MQY(1)S(1)MEY(1)FQFMK 54.776 0.037670999999999996 0.0 3673.6 3017.0 4164.6 7723.3 6869.0 6485.0 4156.8 6922.2 3856.5 5336.4 True False 4841.728384373173 3992.1862493494045 4109.3746828987005 5942.812508795519 5915.357917570691 6079.491924831888 4526.747147211381 5852.5330463315195 4060.3467167992085 5149.574260273743 0.940219159809882 0.7752458839455957 0.7980028008529492 1.154039578502866 1.1487081491774118 1.1805814650993522 0.879052698032312 1.1365081365037755 0.7884820203725671 1.0 12.330237447447066 -5.749880581558595 24.99632906460344 1.0502902769283042 0.8315648794323431 0.3477284808218748 0.12702690394677607 232.2148582006836 502168.73319598404 0.03438368683783526 0.05891564228416681 1.7787684527585537e-06 5.749880581558595 -0.2187253974959611 MQYAPNTQVEILPQGHES(ph)PIFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MQYAPNTQVEILPQGHESPIFK 22 0 H7C0X8;P40121-2;P40121 H7C0X8 CAPG Macrophage-capping protein 1 MQYAPNT(0.001)QVEILPQGHES(0.999)PIFK 64.574 0.0021936 4117400.0 15370.0 12824.0 9978.7 13960.0 14647.0 11083.0 11010.0 12101.0 12340.0 10430.0 True False 17971.837428662468 14097.081969136534 10216.630052430484 13177.866458930652 11777.02549436927 10501.78796949357 9967.053094502831 11783.361572069325 12520.449155013603 12320.876436165425 1.4586492707539698 1.144162271423924 0.8292129302134421 1.06955593031107 0.9558593948560518 0.8523572185715383 0.8089565012799395 0.9563736502933887 1.0161979320125614 1.0 13.588817264245925 -4.886591053222822 2.7333546754531803 0.9327035166490624 1.5014644497354068 0.7962683546176919 0.081586796036593 0.1534848660954869 1.8356111399456434 0.021951696862717775 0.17947913435129512 1.298401315335751e-05 4.886591053222822 0.5687609330863445 MREDYDS(ph)VEQDGDEPGPQR ddPTM_PC-9_AZD4547_30min_R2 2 MREDYDSVEQDGDEPGPQR 19 1 Q9Y5S9;Q9Y5S9-2 Q9Y5S9 RBM8A RNA-binding protein 8A 1 MREDYDS(1)VEQDGDEPGPQR;MREDY(0.001)DS(0.999)VEQDGDEPGPQR 71.634 0.0029131 12439000.0 20112.5 20410.4 32428.0 35654.0 33108.0 29536.0 25300.1 29648.7 25734.1 30654.0 True False 26507.856634011718 27007.66265287408 31997.983531921196 27434.521148808864 28511.525685679197 27689.109250861173 27551.759887211967 25067.174674347658 27094.3519887936 29580.81279035144 0.8961165746824222 0.9130128656127847 1.0817141421603595 0.9274431146718645 0.9638520039239415 0.9360496429595303 0.9314064519619522 0.8474133165983856 0.9159434590529959 1.0 14.85237407338262 -7.132150521609902 2.2814734924177023 0.9099708270311039 0.9591499381317923 0.04700712987578759 0.05880602350548715 0.7132333864554686 7.274937544991666 0.026897351547954654 0.019365140911042775 7.376485250911108e-08 7.132150521609902 0.0491791111006884 MREDYDS(ph)VEQDGDEPGPQR ddPTM_PC-9_Lapatinib_30min_R1 2 MREDYDSVEQDGDEPGPQR 19 1 Q9Y5S9;Q9Y5S9-2 Q9Y5S9 RBM8A RNA-binding protein 8A 1 MREDYDS(1)VEQDGDEPGPQR;MREDY(0.002)DS(0.998)VEQDGDEPGPQR 87.74799999999999 0.00054604 26794000.0 40402.0 38836.0 53390.0 42544.0 49794.0 46377.0 38194.0 46259.0 44151.0 37284.0 True False 39825.86007118061 38746.07762807672 49000.4802913599 45672.827682623574 46865.21481877059 44393.563820067306 40171.4984353227 48408.36201678214 39178.24944935871 43728.48972219279 0.9107531571338137 0.8860602749884721 1.1205619174743988 1.0444638717866355 1.0717318415638277 1.0152091714600648 0.9186573488024017 1.107021127972189 0.8959433471921447 1.0 15.41628590158099 -5.233219231900476 24.829272607251244 1.0242089063086752 0.8984066632803016 0.33875996297646505 0.06882992586180169 717.9388146528538 631670.166172998 0.01693745639523087 0.04479680473038513 5.844949565445384e-06 5.233219231900476 -0.12580224302837362 MREDYDSVEQDGDEPGPQR ddPTM_PC-9_AZD4547_30min_R2 1 MREDYDSVEQDGDEPGPQR 19 1 Q9Y5S9;Q9Y5S9-2 Q9Y5S9 RBM8A RNA-binding protein 8A 0 80.596 0.014674000000000001 6037000.0 10277.0 5105.4 7612.1 14672.0 12557.0 10692.0 7826.4 13089.0 7190.3 11126.0 False True 13544.872225120607 6755.620708461532 7511.158580342214 11289.59708014033 10813.677299597488 10023.427549776809 8522.93443825422 11066.39580529791 7570.3645787116175 10736.482126490831 1.261574514402669 0.6292210641130713 0.6995921468363866 1.051517335672246 1.0071899875766746 0.9335858274327439 0.7938293323494686 1.0307282846392545 0.7051066158842436 1.0 13.390233742515377 -4.734572895128085 24.783227971366347 0.8771486056179011 1.26157670882538 0.3836931484536916 0.14788999889554635 2932.329527724766 2704794.6506465874 0.03762826763419078 3.2416410834133442 1.8425831905195305e-05 4.734572895128085 0.3844281032074789 MREDYDSVEQDGDEPGPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MREDYDSVEQDGDEPGPQR 19 1 Q9Y5S9;Q9Y5S9-2 Q9Y5S9 RBM8A RNA-binding protein 8A 0 ; 103.87 0.0016332999999999999 18548600.0 21565.1 26308.0 28540.0 25233.0 29350.0 26086.7 27677.0 20925.0 24919.0 18824.4 False True 25215.645499860042 28919.684376485046 29220.501838552747 23819.27681648977 23599.078190737902 24718.66752898926 25055.23419587237 20375.74092187015 25283.393232883613 22237.114706131597 1.1339441214874497 1.3005142420077915 1.314041962039957 1.0711496132149696 1.0612473112004392 1.111595090264719 1.1267304471368182 0.9162942760848287 1.136990727754444 1.0 14.44068198824059 -5.774840046368066 24.141725350122723 1.0619953287538333 1.2546014973087583 0.565033885482787 0.07591509537884167 102.24430015610832 184196.25004229712 0.02106477930140763 0.03146284765897559 1.6794224470184674e-06 5.774840046368066 0.19260616855492496 MREDYDSVEQDGDEPGPQR ddPTM_PC-9_Lapatinib_30min_R1 3 MREDYDSVEQDGDEPGPQR 19 1 Q9Y5S9;Q9Y5S9-2 Q9Y5S9 RBM8A RNA-binding protein 8A 0 ;; 212.59 1.2022000000000001e-21 14273000.0 43763.600000000006 38001.2 46984.1 35645.0 37822.3 41023.5 36142.2 35884.3 40197.4 35412.5 False True 43139.52303873869 37913.210556186765 43121.24866187084 38266.45220823425 35597.666675502835 39269.02053544925 38013.466270857236 37551.61558007772 35669.9455146124 41533.5034408098 1.0386680502456929 0.9128343966989834 1.0382280590252582 0.9213393775646331 0.857083167237114 0.9454781629826218 0.9152482483215258 0.9041282932847997 0.8588234210833269 1.0 15.341987950890816 -5.902795536890966 7.768676122267784 0.9084925737697129 0.9878279349460166 0.3493033191647199 0.050670645437349095 0.25631346873922023 18.00254839981539 0.01341962072567006 0.019983703778173798 1.2508477828808284e-06 5.902795536890966 0.07933536117630369 MRGRGNAR ddPTM_PC-9_Lapatinib_30min_R1 1 MRGRGNAR 8 2 Q8N6Y1 Q8N6Y1 PCDH20 Protocadherin-20 0 98.41799999999999 0.011545 3504600.0 7440.1 8924.3 4645.3 7780.1 6913.2 3766.7 11625.0 11310.0 8058.3 9488.2 False True 7334.002809652762 8903.636331657355 4263.381365376554 8352.274507652777 6506.579167874144 3605.60702160656 12226.885618438144 11835.50388918494 7150.6893963390885 11128.222727768212 0.6590452931313329 0.8000950870115265 0.38311430941601793 0.7505488263468504 0.5846916733287789 0.3240056485039163 1.0987276151409553 1.0635574232039633 0.64257245485355 1.0 13.441935579904479 -7.273935308596405 24.99726401895218 0.956510829046918 0.591952375532524 0.5025301940987396 0.17904537818272265 675.594795255563 1351476.5028579575 0.07437761773116568 0.05053696967659742 5.321875266659597e-08 7.273935308596405 -0.364558453514394 MRKET(ph)PPPLVPPAAR ddPTM_PC-9_AZD4547_30min_R2 1 MRKETPPPLVPPAAR 15 2 Q9BQA1-2;Q9BQA1 Q9BQA1-2 WDR77 Methylosome protein 50 1 MRKET(1)PPPLVPPAAR 51.76 0.042591000000000004 13020000.0 10779.0 10276.0 14733.0 27058.0 23557.0 18862.0 13615.0 19363.0 10253.0 16719.0 True False 14206.49778287196 13597.516041867575 14537.63079362882 20820.19614193274 20286.517173418655 17682.556158238873 14826.70862425013 16370.89326747526 10794.952648085638 16133.672898867544 0.8805495110706716 0.8428035033995274 0.9010738524796326 1.2904808639943453 1.257402285306194 1.0960031400834989 0.9189915227109164 1.0147034323860853 0.6690945524774683 1.0 13.977787291061027 -11.14004416447585 15.752020505305682 1.000000001788846 0.9980813703554478 0.0 0.18012015698406914 1.228414729567232e-08 2.6868604606930774e-10 0.18935190290617573 0.045924539352567316 7.243622941430934e-12 11.14004416447585 -0.0019186314333982102 MRKET(ph)PPPLVPPAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MRKETPPPLVPPAAR 15 2 Q9BQA1-2;Q9BQA1 Q9BQA1-2 WDR77 Methylosome protein 50 1 MRKET(1)PPPLVPPAAR;MRKET(1)PPPLVPPAAR 63.336999999999996 0.019828 31450300.0 33077.0 23762.0 22217.8 40019.0 35455.0 40056.0 32847.0 27673.4 32652.0 20668.8 True False 38676.28279947095 26120.934322412842 22747.55661347572 37776.86517334855 28507.847265847086 37955.39284544205 29735.494368313764 26947.002572390982 33129.47372848492 24415.889825869228 1.584061980755356 1.0698333957395678 0.9316701859202416 1.547224591967279 1.1675940327860723 1.554536538137037 1.2178746947329475 1.103666618934362 1.3568816850321563 1.0 14.575532736839826 -10.249314392520251 6.097482125083124 0.9999999953610936 1.27036562441909 0.13256585814158128 0.21431940178480904 1.315731101141614e-08 2.7334686223866325e-09 0.20336762826249094 0.049323893730325134 5.632297774259061e-11 10.249314392520251 0.2703656290579963 MRLPLVS(ph)RS(ph)TVSKSIK ddPTM_PC-9_Lapatinib_30min_R1 1 MRLPLVSRSTVSKSIK 16 3 G5E9Y6 G5E9Y6 SPATA4 2 MRLPLVS(1)RS(1)TVSKSIK 59.708999999999996 0.02075 27276000.0 51346.0 37188.0 197900.0 73189.0 115370.0 130620.0 68646.0 90046.0 168000.0 76143.0 True False 50613.79662429679 37101.89347082391 181629.42591609195 78571.56321134689 108584.163426147 125033.68709009196 72200.15399254233 94229.8658890846 149078.07088157162 89304.21609583023 0.5667570786353954 0.41545511615051584 2.033828119841394 0.8798191915937498 1.21589067317525 1.4000871689632357 0.808474192473355 1.0551558482744956 1.6693284751707522 1.0 16.446440666844033 -5.185630424660849 24.999998927070685 1.233837483236895 0.49110159598899633 0.4258479528317509 0.3552347336976421 117.95181144822517 38896.53680147261 0.08678551926641345 0.22961291616964072 6.521831519328618e-06 5.185630424660849 -0.7427358872478986 MRSHS(ph)YLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MRSHSYLR 8 1 O95886 O95886 DLGAP3 Disks large-associated protein 3 1 MRS(0.004)HS(0.603)Y(0.393)LR 60.681999999999995 0.032483 16755000.0 6265.7 6089.0 11296.0 10236.0 12348.0 11096.0 9259.1 12591.0 9139.3 6465.7 True False 7326.3592567840205 6693.475679200907 11565.339480318562 9662.510105559755 9928.49804085968 10514.106226608375 8382.011017921091 12260.499591267248 9272.94497264309 7637.880227546958 0.9592136873737037 0.8763525323505414 1.5142080179009272 1.2650774583647855 1.2999022955415465 1.3765738547048634 1.0974263497469277 1.6052228139226696 1.2140731062002084 1.0 12.898956581360029 -5.246496398269315 24.942715767533777 1.312916231364083 0.9177830370251396 0.4394989867419873 0.17030184223548295 636.4589134784143 1062368.4617571307 0.040097337807537964 0.10513937902542807 5.668962729396709e-06 5.246496398269315 -0.39513319433894334 MRSLQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MRSLQER 7 1 Q8N6G5-2;Q8N6G5 Q8N6G5-2 CSGALNACT2 Chondroitin sulfate N-acetylgalactosaminyltransferase 2 0 68.485 0.039194 0.0 8531.0 4129.7 7937.8 9074.5 12106.0 10364.0 8336.0 10590.0 8589.6 8285.1 False True 9975.129805069591 4539.669323763506 8127.067256274139 8566.085184925947 9733.916203648145 9820.493595220723 7546.353732586337 10312.02372103249 8715.20665007332 9787.123045184484 1.0192096041928902 0.4638410391700491 0.8303836805518517 0.8752403689397449 0.9945635871449968 1.0034096383464453 0.7710492345653442 1.0536317642502995 0.8904768653502753 1.0 13.256669122180373 -5.722076271573074 2.925272582338345 0.9452293678738839 0.7269596424173287 0.2307152522693604 0.1464760245059812 0.3160735637337382 5.502271036170537 0.039734669215464556 0.0721926229154012 1.8963728475758603e-06 5.722076271573074 -0.2182697254565552 MRSLS(ph)ST(ph)S(ph)S(ph)GSK ddPTM_PC-9_Lapatinib_30min_R1 1 MRSLSSTSSGSK 12 1 A0A096LNU0;D6REY2;P23508;P23508-2;A0A096LPB3 A0A096LNU0 MCC Colorectal mutant cancer protein 4 MRSLS(0.645)S(0.645)T(0.71)S(0.667)S(0.667)GS(0.667)K 48.64 0.042515 0.0 3763.8 4408.6 2833.1 4309.4 4449.6 2622.7 3755.1 3880.6 3617.3 2828.2 True False 3710.1275218036135 4398.392157563577 2600.1734540822563 4626.3276517369795 4187.883276250187 2510.5332348123097 3949.5207041545896 4060.9068428267965 3209.881582142311 3317.0506016603817 1.1185019366139526 1.3259948929817107 0.7838811541737453 1.394711208029575 1.2625322249090507 0.7568570806714972 1.1906724311584571 1.2242523043797011 0.9676914728209373 1.0 11.69568530529199 MRT(ph)PSNLAAAR ddPTM_PC-9_AZD4547_30min_R2 1 MRTPSNLAAAR 11 1 Q86U86-8;Q86U86;E7EVG2;Q86U86-5;Q86U86-4;Q86U86-7;Q86U86-9;Q86U86-2;Q86U86-6;H0Y5B5 Q86U86-8 PBRM1 Protein polybromo-1 1 MRT(0.997)PS(0.003)NLAAAR 60.167 0.041868999999999996 3391400.0 21943.0 21459.0 27177.0 34028.0 31440.0 24287.0 20431.0 31960.0 24694.0 28653.0 True False 28920.41755724643 28395.20209638344 26816.615222863642 26183.37032735928 27075.098693903383 22768.330050638728 22249.319419908505 27021.31636773789 25999.27442619984 27649.86719129445 1.045951409356209 1.0269561839097607 0.9698641601904997 0.9469618839834104 0.9792126127256036 0.8234516966434953 0.8046808784280055 0.9772674921290596 0.9403037723951783 1.0 14.7549849304282 -5.533233264046489 1.08033801957239 0.9087247245462035 1.0540048919562153 0.3558907885072161 0.06050413398116994 0.7686303881684445 1.5304779451717432 0.023068605907987642 0.09624222222714676 2.9293194549400254e-06 5.533233264046489 0.14528016741001182 MRT(ph)PSNLAAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MRTPSNLAAAR 11 1 Q86U86-8;Q86U86;E7EVG2;Q86U86-5;Q86U86-4;Q86U86-7;Q86U86-9;Q86U86-2;Q86U86-6;H0Y5B5 Q86U86-8 PBRM1 Protein polybromo-1 1 MRT(0.997)PS(0.003)NLAAAR 70.563 0.020640000000000002 3447000.0 15036.0 22656.0 16092.0 16073.0 19950.0 23397.0 16617.0 19977.0 19295.0 15766.0 True False 17581.297825463163 24905.137951712204 16475.694309249848 15172.481919369078 16040.940712273285 22170.02013193547 15042.917463338195 19452.62491738113 19577.1528724463 18624.250996412677 0.9440002622843516 1.3372423920032717 0.8846366123622005 0.8146626633356443 0.8612931986023503 1.1903845226423209 0.8077059027090914 1.0444782408231081 1.0511645744152163 1.0 14.184894786037567 -3.228813331086382 8.655047098049685 0.9929777521341572 1.0459485140757865 0.0 0.1616088616675199 0.0 0.0 0.03727067028660408 0.0 0.0005904548155509497 3.228813331086382 0.05297076194162931 MRTPPALGSQGS(ph)EVTGPTFADGELIPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MRTPPALGSQGSEVTGPTFADGELIPR 27 1 Q86YS3-2 Q86YS3-2 1 MRT(0.094)PPALGS(0.073)QGS(0.823)EVT(0.008)GPT(0.001)FADGELIPR 46.398999999999994 0.045336 0.0 1103.7 1844.5 1813.0 1953.4 2553.0 4577.4 985.69 2252.7 2082.2 2036.7 True False 1290.534610931344 2027.6097701241706 1856.2287958407892 1843.9573310082476 2052.757976863845 4337.353085947832 892.318307422388 2193.569011932946 2112.648235864611 2405.937587491672 0.5363957143530064 0.8427524390763894 0.7715199286511893 0.7664194368943207 0.8532049989725474 1.8027704078848414 0.37088173527921026 0.9117314694018592 0.8780976891703861 1.0 11.23238350266064 -6.527681366823328 24.998209758328873 0.9905016900146688 0.7490723648751008 0.12047477643141391 0.33428298061715755 332.2073597347092 1729159.700506076 0.11094074509479819 0.11132806990625096 2.967007425185644e-07 6.527681366823328 -0.24142932513956805 MS(ph)ACS(ph)S(ph)SEIS(ph)VK ddPTM_PC-9_Lapatinib_30min_R1 1 MSACSSSEISVK 12 0 B1APG2 B1APG2 PRKACB 4 MS(1)ACS(0.997)S(0.691)S(0.627)EIS(0.684)VK 66.285 0.019886 0.0 3582.0 8146.0 8287.2 6290.5 11800.0 10308.0 9457.8 7100.2 11690.0 10927.0 True False 3530.9200231416517 8127.1384374887475 7605.858405517098 6753.124354492845 11105.947199692599 9867.15086912162 9947.47860662919 7430.101212554453 10373.349098842686 12815.717390687709 0.27551481633851616 0.6341539993222833 0.5934789425868384 0.5269407984448745 0.8665880232161267 0.7699257535353732 0.7761936615313734 0.5797647518314809 0.8094239895130863 1.0 13.645626618773505 -4.5599371905836446 0.5298228362846691 0.7881444333275128 3.4616746086965873e-37 0.5829647990232296 0.12553347464805864 4.337826616274943 0.7848355646629781 0.07282876177020096 2.227497203497781 2.7546270597864788e-05 4.5599371905836446 -0.7881444333275128 MS(ph)ADMSEIEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MSADMSEIEAR 11 0 O43318-3;O43318;Q9UG54;O43318-4;O43318-2 O43318-3 MAP3K7;DKFZp586F0420 Mitogen-activated protein kinase kinase kinase 7 1 MS(0.993)ADMS(0.007)EIEAR 58.781000000000006 0.042212 35737000.0 53255.0 65822.0 68735.0 70701.0 74911.0 69163.0 65667.0 63064.0 64228.0 56935.0 True False 62270.01966580482 72356.37315755647 70373.90307893902 66739.85218573465 60232.727303113 65535.970525496974 59446.54637209054 61408.636821831285 65167.21299256186 67256.8648027879 0.9258537377321168 1.0758213807575103 1.0463452806682407 0.9923128647377596 0.8955625195989848 0.9744131058987515 0.8838732900559824 0.913046378267781 0.968930282189731 1.0 16.03739390835608 -6.055699926038893 5.5574885007838475 0.9342602515029181 1.0218357441777373 0.33298885820198665 0.049368442560723855 0.20608329919479512 13.866515344882353 0.01414067573123401 0.01877172641053061 8.796300836467558e-07 6.055699926038893 0.08757549267481912 MS(ph)ADMSEIEAR ddPTM_PC-9_Lapatinib_30min_R1 5 MSADMSEIEAR 11 0 O43318-3;O43318;Q9UG54;O43318-4;O43318-2 O43318-3 MAP3K7;DKFZp586F0420 Mitogen-activated protein kinase kinase kinase 7 1 MS(0.995)ADMS(0.005)EIEAR;MS(1)ADMSEIEAR;MS(0.995)ADMS(0.005)EIEAR;MS(1)ADMSEIEAR;MS(1)ADMSEIEAR 184.96 0.0011801 42446400.0 148323.7 131199.59999999998 151765.1 119683.6 140781.5 148393.2 144880.5 150036.5 161885.0 117478.79999999999 True False 146208.57683876506 130895.8153870791 139287.55930822747 128485.53119678532 132501.00895707836 142046.76875744452 152381.70338426903 157007.74352517215 143651.80657537616 137784.85404933887 1.0611367834842702 0.9500014808609305 1.0109061715763803 0.9325083811517949 0.9616514810084391 1.030931663262346 1.1059394331520882 1.1395138065679542 1.042580533009357 1.0 17.07205778345982 -7.002758674698836 4.105524270424162 1.0828274036910908 0.9805969453009289 0.421483495124371 0.04829011840812118 0.17888326084871206 7.059678279533643 0.01796501535168911 0.014754034626897873 9.93668048593859e-08 7.002758674698836 -0.10223045839016187 MS(ph)DYSPNSTGSVQNTSR ddPTM_PC-9_AZD4547_30min_R2 1 MSDYSPNSTGSVQNTSR 17 0 H7C1W4;Q93075 H7C1W4 TATDN2 Putative deoxyribonuclease TATDN2 1 MS(0.897)DY(0.001)S(0.085)PNS(0.013)T(0.002)GS(0.001)VQNTSR 140.45 6.5419e-08 0.0 7943.0 6259.4 12993.0 21856.0 17410.0 12434.0 10334.0 12195.0 11943.0 12821.0 True False 10468.70877533648 8282.628640761568 12820.70433052461 16817.436871833903 14992.92201847514 11656.500014396253 11253.705980389346 10310.542963221646 12574.282597882257 12372.14069240869 0.8461517724058764 0.6694580062319879 1.0362559438393026 1.359298870740515 1.211829253418894 0.9421570853577877 0.9096005501533301 0.833367742863448 1.016338474521034 1.0 13.594807524093646 -5.274345524484142 23.19684286899725 1.0422427977004973 0.7578049101276535 0.3657115638092988 0.1478599720437381 307.9052266515874 553415.0900725846 0.044387716653436236 0.09354796753566226 5.316850825496215e-06 5.274345524484142 -0.28443788757284383 MS(ph)GFIYQGK ddPTM_PC-9_AZD4547_30min_R2 5 MSGFIYQGK 9 0 B1ALK7;A0A2R8YG42;Q14155-1;Q14155-5;Q14155-6;Q14155-2;Q14155-3;Q14155;E7EUY6;E9PDQ5;Q15052-2;Q15052;F6SJA5 B1ALK7 ARHGEF7;ARHGEF6 Rho guanine nucleotide exchange factor 7;Rho guanine nucleotide exchange factor 6 1 MS(1)GFIYQGK;MS(1)GFIYQGK;MS(1)GFIYQGK;MS(1)GFIYQGK;MS(1)GFIYQGK 96.756 0.0050028 228585000.0 574247.0 499110.0 676244.0 919587.0 780645.0 641228.0 625744.0 674237.0 626315.0 656207.0 True False 756845.6009203877 660437.5468719851 667276.5627100191 707590.4246275226 672265.9166635555 601131.9117927687 681434.0037732468 570049.1640749213 659420.7322525863 633233.3926638654 1.1952079749561446 1.0429607069419984 1.0537608572771913 1.1174243696322685 1.0616400279137042 0.9493054516028393 1.0761182396061153 0.9002196831042931 1.0413549567854545 1.0 19.27237781039249 -6.581637005125928 5.717573067540977 0.9927395950237401 1.094164055547976 0.4311378287603631 0.05904057735791205 0.19645872779014947 13.047480795881995 0.01875847841904729 0.01884542545596361 2.6203722699780707e-07 6.581637005125928 0.10142446052423582 MS(ph)GFIYQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 MSGFIYQGK 9 0 B1ALK7;A0A2R8YG42;Q14155-1;Q14155-5;Q14155-6;Q14155-2;Q14155-3;Q14155;E7EUY6;E9PDQ5;Q15052-2;Q15052;F6SJA5 B1ALK7 ARHGEF7;ARHGEF6 Rho guanine nucleotide exchange factor 7;Rho guanine nucleotide exchange factor 6 1 MS(1)GFIYQGK;MS(1)GFIYQGK;MS(1)GFIYQGK;MS(1)GFIYQGK;MS(1)GFIYQGK 96.113 0.005209 203361000.0 507607.0 520649.0 499812.0 594886.0 566444.0 539078.0 526184.0 497288.0 473853.0 401784.0 True False 593534.8394047538 572335.591870632 511729.41362756613 561556.4660664338 455453.364452277 510807.80068741826 476340.0422777358 484234.7169201887 480782.2036831982 474624.2586796061 1.2505362474643715 1.2058709208476968 1.0781779571301007 1.1831600593460418 0.9596082714342035 1.0762361833515925 1.0036150356134408 1.020248560971828 1.0129743579072914 1.0 18.85642631492307 -4.804054502406116 0.5147131524854773 1.003699344550313 1.4307736518724412 0.7434434957290792 0.04815026323509942 2.064829351811075 0.42683947750967294 0.028218755583887277 0.5345309220419686 1.5701657417767557e-05 4.804054502406116 0.42707430732212814 MS(ph)GFIYQGK ddPTM_PC-9_Lapatinib_30min_R1 5 MSGFIYQGK 9 0 B1ALK7;A0A2R8YG42;Q14155-1;Q14155-5;Q14155-6;Q14155-2;Q14155-3;Q14155;E7EUY6;E9PDQ5;Q15052-2;Q15052;F6SJA5 B1ALK7 ARHGEF7;ARHGEF6 Rho guanine nucleotide exchange factor 7;Rho guanine nucleotide exchange factor 6 1 MS(1)GFIYQGK;MS(1)GFIYQGK;MS(1)GFIYQGK;MS(1)GFIYQGK;MS(1)GFIYQGK 117.14 0.0018763999999999999 171711000.0 1133982.0 1127500.0 1155685.0 977825.0 1068283.0 1089411.0 953466.0 1009112.0 1115669.0 818999.0 True False 1117811.2087331717 1124889.343023391 1060669.040373111 1049737.5124285754 1005448.6942651876 1042819.4310710761 1002831.804135032 1055999.0274644743 990010.6087045943 960561.8859024289 1.1637055614412706 1.1710743050840287 1.1042172877561485 1.0928369403730482 1.0467297412291021 1.0856348210103797 1.0440054085561508 1.0993555365486776 1.0306578089703184 1.0 19.873519039507606 -1.5228787452852617 0.23271834738283245 1.021914578863655 1.9350622781662141 0.7829978396740158 0.024450749607437126 23.329695738541588 0.3071604922639837 0.03516996694465764 8.145461683257494 0.029999999999659854 1.5228787452852617 0.9131476993025591 MS(ph)GGSTMSSGGGNTNNSNSK ddPTM_PC-9_AZD4547_30min_R2 1 MSGGSTMSSGGGNTNNSNSK 20 0 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 MS(0.596)GGS(0.151)T(0.151)MS(0.102)S(0.001)GGGNTNNSNSK 104.55 9.352e-05 2058300.0 2973.3 1151.0 3522.6 5239.2 5691.4 4830.3 2885.4 4045.1 3777.2 4024.8 True False 3918.747551518064 1523.0382409682343 3475.8880223740484 4031.3833848330974 4901.247350715067 4528.260577411795 3142.195010239539 3420.022742150705 3976.855080693365 3883.8929770537784 1.0089741336000266 0.3921421753808397 0.8949494857118251 1.0379748897950327 1.2619419174709154 1.1659076612473542 0.8090323365766704 0.8805656495573796 1.0239352897180254 1.0 11.923287731659906 -5.5088880327855865 15.21746546086241 1.022639436650794 0.6862967706773999 0.33263504328202254 0.1830304428067824 4.096453519131437 4451.542492775166 0.049494054872708367 0.09585636125470205 3.098217960344609e-06 5.5088880327855865 -0.33634266597339413 MS(ph)GGSTMSSGGGNTNNSNSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MSGGSTMSSGGGNTNNSNSK 20 0 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 MS(0.431)GGS(0.132)T(0.233)MS(0.198)S(0.006)GGGNTNNSNSK 97.20299999999999 0.0014918 0.0 3143.8 4537.1 3049.9 3170.4 3791.0 3343.3 2952.0 2504.9 2649.1 2809.5 True False 3675.983247119653 4987.513303350703 3122.621182810161 2992.7727665754815 3048.180763921204 3167.971462456721 2672.3651893707865 2439.1490291609334 2687.8380758951785 3318.840110010239 1.1076108294678624 1.5027880639104712 0.9408772581094685 0.9017526206064348 0.9184476090690008 0.9545417547840072 0.8052105858641505 0.7349402045021711 0.8098727226382972 1.0 11.696463411803 -5.394405270058641 5.678004157324766 0.8701747417377562 1.3016258729538535 0.6844753036773328 0.11513041712434928 0.11499544724915145 4.778241826371316 0.029967482694211775 0.06360543542254696 4.03268899375731e-06 5.394405270058641 0.43145113121609724 MS(ph)GGSTMSSGGGNTNNSNSK ddPTM_PC-9_Lapatinib_30min_R1 3 MSGGSTMSSGGGNTNNSNSK 20 0 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 MS(0.578)GGS(0.088)T(0.088)MS(0.218)S(0.027)GGGNTNNSNSK;MS(0.666)GGS(0.156)T(0.156)MS(0.019)S(0.004)GGGNTNNSNSK;MS(0.711)GGS(0.282)T(0.007)MSSGGGNTNNSNSK 130.72 2.2240000000000002e-06 2044160.0 9734.699999999999 14402.599999999999 11534.8 10111.1 15750.099999999999 13439.5 15214.5 10995.6 13499.2 11348.0 True False 9595.881392874651 14369.25166459311 10586.453269615622 10854.704023640825 14823.710083887996 12864.72391400466 16002.23236487976 11506.49571741131 11978.777943122079 13309.486679740477 0.7209805775215489 1.079624782709749 0.7954065791079816 0.8155614325955719 1.1137702332616966 0.9665830263451987 1.2023177715214324 0.8645333959367751 0.9000180270931121 1.0 13.700167310012352 -6.2472021153348525 24.88325217245252 1.008755081761722 0.8649822467415547 0.2664586748067953 0.125325406814709 1158.6722834378572 2025074.3977977922 0.0369528977190962 0.04749553280193553 5.659758295157209e-07 6.2472021153348525 -0.14377283502016724 MS(ph)LPDVDLDLKGPK ddPTM_PC-9_AZD4547_30min_R2 1 MSLPDVDLDLKGPK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 MS(1)LPDVDLDLKGPK 51.888000000000005 0.044024 2007700.0 8592.2 8958.5 8414.1 14733.0 13884.0 9846.7 9213.1 9888.2 8696.8 9753.9 True False 11324.340871137623 11854.159931984306 8302.523536324725 11336.534472580945 11956.446255284816 9230.984292404342 10033.048051860367 8360.205898231101 9156.495093130914 9412.418929856098 1.2031275865991184 1.259416949067474 0.8820818110835679 1.2044230667019689 1.2702841155273157 0.9807239096767945 1.065937260828419 0.8882101360483023 0.9728099823613464 1.0 13.200349818417621 -6.7894346088049495 24.375489842891014 0.9798242891267827 1.1557734416455767 0.4089257660665213 0.1093785432881995 181.90744504331792 158385.55146887965 0.03992055514900548 0.0352148852246648 1.6239228441746401e-07 6.7894346088049495 0.17594915251879406 MS(ph)LPLLAGGVADDINTNKK ddPTM_PC-9_AZD4547_30min_R2 2 MSLPLLAGGVADDINTNKK 19 1 Q15398-1;Q15398;Q15398-3 Q15398-1 DLGAP5 Disks large-associated protein 5 1 MS(1)LPLLAGGVADDINTNKK;MS(1)LPLLAGGVADDINTNKK 140.17 7.7818e-05 22608700.0 28944.0 49441.0 47874.0 52379.0 53520.0 61965.0 51168.0 70129.0 48506.0 60505.0 True False 38147.589927400106 65421.836378549495 47239.15947968409 40303.83079748298 46089.67182244622 58090.31875438831 55721.85287444958 59292.174454101754 51069.92813303836 58386.73836628872 0.6533605232078818 1.1204913685728795 0.8090734437558339 0.6902908421538677 0.7893859652392816 0.9949231688531593 0.9543580346084584 1.015507564100135 0.874683696367 1.0 15.833353100266933 -6.762960044006266 24.990952623363825 0.9680176999112049 0.8226478856184278 0.28642777165857214 0.12209744462188321 60.20849330872799 989467.0615269124 0.04246307696594743 0.0394598696255485 1.7259966799626258e-07 6.762960044006266 -0.14536981429277707 MS(ph)LPLLAGGVADDINTNKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MSLPLLAGGVADDINTNKK 19 1 Q15398-1;Q15398;Q15398-3 Q15398-1 DLGAP5 Disks large-associated protein 5 1 MS(1)LPLLAGGVADDINTNKK 56.766000000000005 0.010404 6631700.0 28463.0 40276.0 39278.0 38425.0 45417.0 29526.0 39385.0 26766.0 21996.0 30192.0 True False 33281.223730124926 44274.33510518896 40214.5364826445 36272.17182553084 36517.86487866247 27977.604582447635 35654.16767729281 26063.420860921222 22317.64988765633 35665.570600259525 0.9331470987283953 1.241374646754335 1.1275450190709095 1.0170080336599716 1.0238968356333191 0.7844429266538653 0.9996802820542389 0.7307725748464983 0.6257477312726334 1.0 15.122244434439244 -6.62619296602702 1.1167484319997512 0.7984359772084265 1.1128957231110344 0.4493872056626871 0.13111258704244486 0.41352567382796757 1.0982944231928722 0.06444642158524853 0.06654477558847681 2.364868703902478e-07 6.62619296602702 0.31445974590260783 MS(ph)LPLLAGGVADDINTNKK ddPTM_PC-9_Lapatinib_30min_R1 1 MSLPLLAGGVADDINTNKK 19 1 Q15398-1;Q15398;Q15398-3 Q15398-1 DLGAP5 Disks large-associated protein 5 1 MS(1)LPLLAGGVADDINTNKK 121.48 1.7454e-05 13230000.0 64792.0 69633.0 65922.0 70519.0 65120.0 66688.0 61846.0 52378.0 61504.0 47052.0 True False 63868.05419860244 69471.76906673893 60502.14762627882 75705.202504488 61289.76963084593 63835.909697320785 65048.083265197936 54811.67309528985 54576.77185416767 55184.875507150915 1.15734707402441 1.258891470322094 1.0963537938658372 1.3718469382915983 1.1106262190064002 1.1567645865043015 1.1787302710643777 0.9932372337813338 0.988980610223458 1.0 15.751985301975738 -7.748678928023084 5.402679033652814 0.9913992893555426 1.1927544778697525 0.5941506754926767 0.07427275475830927 0.11311829229907151 9.865432155746355 0.03705305742242038 0.019442808782032337 1.7836969593420612e-08 7.748678928023084 0.20135518851420997 MS(ph)PGVAGSPR ddPTM_PC-9_AZD4547_30min_R2 2 MSPGVAGSPR 10 0 E7EWM1;Q15596 E7EWM1 NCOA2 Nuclear receptor coactivator 2 1 MS(1)PGVAGSPR;MS(1)PGVAGSPR 90.601 0.0075786000000000004 5244300.0 37558.0 37238.0 48544.0 71459.0 58208.0 50741.0 47931.0 64110.0 56741.0 58497.0 True False 49500.66274506956 49274.45527122076 47900.27484191385 54985.23158054447 50126.82394321654 47568.157248711665 52196.76614534949 54203.272601241435 59740.21342095268 56449.03783510108 0.8769088835432569 0.8729015969264399 0.8485578617272472 0.974068534899874 0.8880013879004813 0.842674367412032 0.9246706081656639 0.9602160582361036 1.058303484205803 1.0 15.784661370249086 -7.879767820354019 2.2321584082961428 1.0270447046645839 0.8865496001632244 0.6927982087689442 0.037615395248170376 0.18097052830897004 1.7376527710474996 0.028532252623689514 0.010833829640012786 1.3189616846826115e-08 7.879767820354019 -0.1404951045013595 MS(ph)PGVAGSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MSPGVAGSPR 10 0 E7EWM1;Q15596 E7EWM1 NCOA2 Nuclear receptor coactivator 2 1 MS(1)PGVAGSPR;MS(1)PGVAGSPR 96.756 0.0047626000000000005 4998100.0 39628.0 51340.0 56736.0 50224.0 61050.0 55995.0 50546.0 42669.0 36038.0 38964.0 True False 46336.23771132312 56436.695905760316 58088.801412478235 47410.11210840495 49087.69075109197 53058.52362643619 45757.91695865035 41548.98396154252 36564.98757280228 46027.86476114573 1.0066997014043046 1.2261419511556655 1.2620355455096781 1.0300306641299173 1.0664776870668393 1.1527478822181942 0.9941351221939964 0.9026919709865829 0.7944098159354221 1.0 15.490219896846043 -7.511080025802632 2.498856879077638 0.8844420713319774 1.1287071258709611 0.5662191381899826 0.08868577096723561 0.21130831807915146 2.631849435058057 0.0493239557455585 0.027007946077568984 3.08261987519974e-08 7.511080025802632 0.24426505453898373 MS(ph)PLSAAR ddPTM_PC-9_AZD4547_30min_R2 1 MSPLSAAR 8 0 C9JB06;Q8N5I4 C9JB06 DHRSX Dehydrogenase/reductase SDR family member on chromosome X 1 MS(0.859)PLS(0.141)AAR 78.264 0.022374 6470700.0 41375.0 44113.0 56890.0 53302.0 58793.0 56377.0 53253.0 51882.0 53965.0 57010.0 True False 54531.38934653744 58371.664573268215 56135.601428734364 41014.04740769083 50630.60679105161 52851.737277755965 57992.41383526933 43864.829029755274 56817.47972826895 55014.09725249346 0.9912257415814609 1.0610310354701418 1.0203857598733945 0.7455188661817387 0.9203205963496351 0.9606944386488231 1.054137334456413 0.7973379773630138 1.032780370229446 1.0 15.747513733282188 -5.563276410867194 24.999997927514784 0.9242601270703967 1.0297745656310122 0.17544876818170663 0.09286812622901579 224.74501778111835 139081.90856715466 0.024843900991557043 0.04303098299087201 2.733528392309823e-06 5.563276410867194 0.10551443856061549 MS(ph)PMGTASGSNSPTSDSASVQR ddPTM_PC-9_AZD4547_30min_R2 11 MSPMGTASGSNSPTSDSASVQR 22 0 Q5QPB1;O76080 Q5QPB1 ZFAND5 AN1-type zinc finger protein 5 1 MS(1)PMGTASGSNSPTSDSASVQR;MS(0.756)PMGT(0.243)AS(0.001)GSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(0.983)PMGT(0.016)AS(0.001)GSNSPTSDSASVQR;MS(0.983)PMGT(0.017)ASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(0.999)PMGT(0.001)ASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR 257.81 1.2236999999999999e-73 131079800.0 98951.62999999999 108330.57 152031.33000000002 218512.40000000002 185457.8 163802.12 124209.8 183493.7 136490.44 149333.2 True False 130416.19001823614 143346.3082327422 150015.2952286938 168137.74216292656 159710.18570465018 153559.5475420731 135264.2315737336 155138.96493075095 143705.04600764424 144105.09012148847 0.9050075185289302 0.9947345240330748 1.0410131599253205 1.1667717082108429 1.1082896903225679 1.0656080740285718 0.9386499218015023 1.0765682516832704 0.9972239418225479 1.0 17.136761770139152 -4.894194885906672 2.320097613223219 1.0545749983510364 0.8884979346846124 0.35285054519619596 0.0599714916054583 0.5258252820770059 4.159747007478154 0.01706218122687898 0.16357580811017575 1.275866146392549e-05 4.894194885906672 -0.16607706366642405 MS(ph)PMGTASGSNSPTSDSASVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 MSPMGTASGSNSPTSDSASVQR 22 0 Q5QPB1;O76080 Q5QPB1 ZFAND5 AN1-type zinc finger protein 5 1 MS(0.827)PMGT(0.154)AS(0.018)GSNS(0.001)PTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(0.998)PMGT(0.001)ASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(0.574)PMGT(0.426)ASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR 236.12 1.7963999999999995e-125 81428300.0 55316.399999999994 58500.299999999996 64342.5 73165.1 84068.9 66920.1 69215.1 63936.99999999999 59137.4 51761.0 True False 64680.37397129897 64307.82316898611 65876.66922029 69065.89665145455 67596.20253864821 63410.69214989681 62658.54465407117 62258.72149685125 60002.172598030884 61144.85956014945 1.0578219401693376 1.0517290191128035 1.0773868759234906 1.1295454294651377 1.1055091634015848 1.0370567960421662 1.0247557211646332 1.0182167715277204 0.9813118065796769 1.0 15.899943596228418 -7.087564871220476 2.253419913593319 1.0051211255022259 1.0841988602675197 0.7043004031187033 0.023844867221587417 0.2013007898231417 2.0152343543130136 0.011975578640853453 0.008878068663357537 8.174009324166809e-08 7.087564871220476 0.07907773476529378 MS(ph)PMGTASGSNSPTSDSASVQR ddPTM_PC-9_Lapatinib_30min_R1 15 MSPMGTASGSNSPTSDSASVQR 22 0 Q5QPB1;O76080 Q5QPB1 ZFAND5 AN1-type zinc finger protein 5 1 MS(1)PMGTASGSNSPTSDSASVQR;MS(0.953)PMGT(0.047)ASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(0.999)PMGT(0.001)ASGSNSPTSDSASVQR;MS(0.96)PMGT(0.04)ASGSNSPTSDSASVQR;MS(0.973)PMGT(0.027)ASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR 324.71 6.357199999999997e-188 130017200.0 224552.09999999998 221386.5 244506.8 200115.09999999998 217060.5 234725.40000000002 185845.39999999997 208551.9 222549.90000000002 159011.90000000002 True False 221349.9458761883 220873.89316119597 224404.39472754268 214832.23201840423 204293.42814736208 224686.74181363216 195467.56546347387 218241.982630142 197483.98670765865 186496.8950449621 1.1868827404489688 1.1843301364773178 1.2032607549495211 1.151934631225956 1.095425358680151 1.2047747055491889 1.0481009102931664 1.1702177807170815 1.0589130004553036 1.0 17.50879208593328 -11.08378967607148 0.07643543105704068 0.6624639449899734 1.3644169233043428 0.6127981862430167 0.043601929203665866 71.58801968534893 0.8770762886039082 6.599358609405356 2.2373307132809432 8.245373324848393e-12 11.08378967607148 0.7019529783143694 MS(ph)PNQLCSVPLQPGR ddPTM_PC-9_AZD4547_30min_R2 1 MSPNQLCSVPLQPGR 15 0 Q86TB9-4 Q86TB9-4 PATL1 Protein PAT1 homolog 1 1 MS(0.998)PNQLCS(0.002)VPLQPGR 101.35 0.0014891 6273700.0 12181.0 14714.0 15871.0 17745.0 18408.0 16728.0 14025.0 18873.0 12714.0 17137.0 True False 16054.304619460368 19470.012752047445 15660.540170072823 13654.164407517052 15852.366945209087 15681.995515587949 15273.19782997488 15956.611508395405 13386.036083854566 16537.038846096842 0.9708089077416413 1.177357865168398 0.9469978462177409 0.8256716655618052 0.9585976723366436 0.9482952577866922 0.923575131685667 0.9649013742361479 0.809457860529487 1.0 14.01341330544264 -5.438403947538275 7.834110814779312 0.9177329516149808 1.0727289715631745 0.4141535834440385 0.07292457631309596 0.2553611423182774 21.218891197011242 0.01791816458037011 0.03741005052175823 3.644148384095417e-06 5.438403947538275 0.15499601994819368 MS(ph)PNQLCSVPLQPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MSPNQLCSVPLQPGR 15 0 Q86TB9-4 Q86TB9-4 PATL1 Protein PAT1 homolog 1 1 MS(1)PNQLCSVPLQPGR 107.03 0.00077638 5418200.0 10436.0 15202.0 17651.0 14048.0 19402.0 16517.0 17184.0 16569.0 13657.0 13737.0 True False 12202.608679604522 16711.154093482033 18071.86678179027 13260.936104230499 15600.317378422367 15650.81944348328 15556.207118613684 16134.081306306634 13856.707788494383 16227.409357967841 0.7519751557640285 1.0298103489499184 1.1136630859020502 0.8171936636157656 0.9613560017059923 0.964468147578871 0.9586377452772774 0.9942487399188348 0.8539075759305094 1.0 13.986145077233502 MS(ph)PNQLCSVPLQPGR ddPTM_PC-9_Lapatinib_30min_R1 2 MSPNQLCSVPLQPGR 15 0 Q86TB9-4 Q86TB9-4 PATL1 Protein PAT1 homolog 1 1 MS(0.848)PNQLCS(0.152)VPLQPGR;MS(0.999)PNQLCS(0.001)VPLQPGR 108.68 0.00062436 9343100.0 31791.0 34682.0 37604.0 31502.0 32820.0 35531.0 31552.0 29802.0 37854.0 30009.0 True False 31337.654510244596 34601.69595985575 34512.34427563773 33818.762167591376 30889.592126602638 34011.42195680641 33185.608174878325 31186.709717549926 33590.48389970837 35196.01566552095 0.8903750585877788 0.9831140061047475 0.9805753186275298 0.9608690508886558 0.8776445726174338 0.9663429599539869 0.9428796853101734 0.8860863688074029 0.95438313867483 1.0 15.10312449861257 MS(ph)PPPSGFGER ddPTM_PC-9_AZD4547_30min_R2 1 MSPPPSGFGER 11 0 A0A087WZ13;Q8IY67-2;E9PAU2;K7EQG2 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 MS(0.967)PPPS(0.033)GFGER 70.685 0.027833 6109600.0 28569.0 31376.0 46689.0 43715.0 46262.0 39913.0 42179.0 53938.0 42140.0 44063.0 True False 37653.347727884684 41517.67840887867 46069.87335394934 33637.18214001737 39839.31984024679 37417.233800434136 45932.84928844997 45603.12147193516 44367.434369484945 42520.367781733374 0.8855367366803552 0.9764186100646699 1.0834777721217366 0.7910839885648356 0.9369467367909655 0.8799837760695116 1.0802552208445992 1.0725006356018898 1.0434395722358982 1.0 15.37586645512468 -7.268282666408087 24.884246978941615 1.0550905823038073 0.9294668161933685 0.4040668714518265 0.07322234471740544 544.2270739736995 1978963.9125331386 0.030896459585031885 0.02135740563273563 5.391595890158024e-08 7.268282666408087 -0.1256237661104388 MS(ph)PPPSGFGER ddPTM_PC-9_Lapatinib_30min_R1 1 MSPPPSGFGER 11 0 A0A087WZ13;Q8IY67-2;E9PAU2;K7EQG2 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 MS(0.992)PPPS(0.008)GFGER 65.241 0.045183999999999995 7834100.0 10145.0 22325.0 25104.0 19351.0 24583.0 20326.0 18369.0 23156.0 22852.0 20700.0 True False 10000.33043963485 22273.307834143918 23040.046024242358 20774.137093043642 23137.076272037568 19456.704362220233 19320.05693979271 24231.91229513408 20278.167117771853 24277.967418983768 0.4119097067333261 0.9174288543087697 0.9490105010284577 0.855678596751046 0.9530071390550554 0.8014140568870841 0.7957856029037135 0.998103007428304 0.8352497870936125 1.0 14.567360022012043 -4.759895727925342 24.999979776095408 0.8959385115778684 0.4119091124793048 0.8048574311810872 0.07216034719553367 16.289587485123437 263729.46662553796 0.017434139771595678 0.10720074395393211 1.7382181166960943e-05 4.759895727925342 -0.48402939909856363 MS(ph)PSGGAPQTTPTLR ddPTM_PC-9_AZD4547_30min_R2 3 MSPSGGAPQTTPTLR 15 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 MS(1)PSGGAPQTTPTLR;MS(0.998)PS(0.002)GGAPQTTPTLR;MS(1)PSGGAPQTTPTLR 119.74 8.1367e-05 22674900.0 46039.0 54001.0 54744.0 74855.0 82847.0 94309.0 68735.0 107280.0 81060.0 82274.0 True False 60678.444329310885 71455.76720288946 54018.05879090585 57598.33624822147 71345.12409331478 88411.84332135254 74852.28184266134 90702.34104915263 85344.66611273027 79393.61230225676 0.7642736307085262 0.9000190963833791 0.6803829328895568 0.7254782164204946 0.8986254942236303 1.1135888739356357 0.9427998005392892 1.1424387733340913 1.074956330086323 1.0 16.276735318018837 -6.545910589702803 3.8872558904087198 1.055751326566636 0.772779238415799 0.7693559333530176 0.07410053585040036 0.10626062346015619 3.5602287594468227 0.02524339374952624 0.026273484211730803 2.84504677064384e-07 6.545910589702803 -0.2829720881508371 MS(ph)PSGGAPQTTPTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MSPSGGAPQTTPTLR 15 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 MS(0.998)PS(0.002)GGAPQTTPTLR;MS(0.997)PS(0.003)GGAPQTTPTLR 90.853 0.0036010999999999994 12214400.0 30865.0 43184.0 48345.0 41648.0 49344.0 44837.0 61117.0 40819.0 44737.0 41988.0 True False 36089.83488846241 47471.022126886484 49497.72814943352 39314.597584637806 39675.39741886784 42485.668788972594 55327.555311237906 39747.54450130552 45391.193990911146 49600.09202317489 0.7276162889294636 0.9570752833423448 0.9979362160519069 0.7926315452452922 0.7999057219557196 0.8565643138146157 1.1154728359251218 0.8013602975319901 0.9151433422684538 1.0 15.598055176799804 MS(ph)PSGGAPQTTPTLR ddPTM_PC-9_Lapatinib_30min_R1 2 MSPSGGAPQTTPTLR 15 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 MS(0.995)PS(0.005)GGAPQTTPTLR;MS(0.975)PS(0.024)GGAPQT(0.001)TPTLR 82.57799999999999 0.0067388000000000005 11433100.0 19392.2 32033.0 30220.0 24967.0 53788.0 48081.0 52454.0 49694.0 44692.0 46674.0 True False 19115.663671906066 31958.82955660167 27735.428252573456 26803.156467470442 50624.29559127672 46024.687712285326 55169.81146060683 52002.96465686615 39658.31633237616 54741.53871080431 0.34919850852006135 0.5838131391490092 0.5066614659682435 0.4896310388546005 0.924787588794705 0.8407635005554102 1.0078235424120074 0.9499726511451231 0.7244647714761592 1.0 15.7403483670336 -6.260095796223847 24.896602156805255 0.9070998030008315 0.49131334137238414 0.8320931525007321 0.09363437135066927 44.59379981550785 826322.256871797 0.027662798727247414 0.03376897209185048 5.49419670072837e-07 6.260095796223847 -0.41578646162844735 MS(ph)PSTFQIT(ph)DMTR ddPTM_PC-9_AZD4547_30min_R2 1 MSPSTFQITDMTR 13 0 Q9NP31-4 Q9NP31-4 2 MS(1)PS(0.003)T(0.01)FQIT(0.982)DMT(0.006)R 98.654 0.022866 0.0 758.97 0.0 1094.2 1207.0 1497.4 1237.5 1093.7 1001.3 957.86 830.29 True False 1000.3066724433002 0.0 1079.6901930624213 928.7447979641076 1289.511857005437 1160.118929372315 1191.0371812223555 846.5720925849799 1008.490524090053 801.221799820607 1.2484766049391918 0.0 1.3475546887318384 1.1591606695824463 1.6094318168753743 1.4479372997989632 1.4865261797532567 1.0566014214472532 1.2586908198402158 1.0 9.646057864626322 -5.306195271540063 24.86695309560665 1.3163346855942941 0.6242378138980478 0.39321611480675445 0.33287649547626735 322.4401723057039 179151.34449194747 0.08159465354979331 0.1698541153213783 4.940884803593101e-06 5.306195271540063 -0.6920968716962463 MS(ph)PTPPLFSLPEAR ddPTM_PC-9_Lapatinib_30min_R1 1 MSPTPPLFSLPEAR 14 0 A0A087WWS1;Q96FV9;J3KRD7;J3QQZ3;J3KT14;Q96FV9-2 A0A087WWS1 THOC1 THO complex subunit 1 1 MS(0.999)PT(0.001)PPLFSLPEAR 98.0 0.0022564 2144400.0 10939.0 11311.0 11369.0 9009.4 9917.2 9657.4 8424.3 7834.9 11848.0 9379.5 True False 10783.007854033081 11284.810074445772 10434.284705609114 9671.981330477354 9333.889793965376 9244.375514498955 8860.469033583526 8198.938056708668 10513.553475028919 11000.734077601852 0.9802080277522502 1.0258233673171244 0.9485080388275122 0.8792123563981137 0.8484788131520905 0.8403416944075626 0.8054434341453601 0.745308267509365 0.9557138097206748 1.0 13.425312177370284 -5.688673254746224 2.159738438937069 0.8492423982410576 1.0036007595741498 0.3751136576300237 0.0694350885377466 0.27658654305299957 2.6168438014828967 0.019976337128741542 0.04111304812331577 2.0479848765884498e-06 5.688673254746224 0.15435836133309222 MS(ph)QGSPGDWAPLDPTPGPPASPNPFVHELHLSR ddPTM_PC-9_Lapatinib_30min_R1 1 MSQGSPGDWAPLDPTPGPPASPNPFVHELHLSR 33 0 Q643R3 Q643R3 LPCAT4 Lysophospholipid acyltransferase LPCAT4 1 MS(0.973)QGS(0.026)PGDWAPLDPT(0.001)PGPPASPNPFVHELHLSR 42.536 0.042339999999999996 0.0 8162.3 7019.2 7080.0 6505.3 5898.6 5108.7 5141.2 5086.4 4489.4 4259.8 True False 8045.904105217501 7002.947473658363 6497.90972959034 6983.721463044639 5551.655945093791 4890.212809961353 5407.386179915199 5322.732712816111 3983.7564965221827 4996.100754173287 1.6104367187744735 1.401682595734031 1.3005962147906203 1.3978343925932788 1.111197755661041 0.9788058829431162 1.0823212833324791 1.065377376220843 0.7973731300743917 1.0 12.286586856099643 -5.7388274301636555 0.5032294936886174 0.9306980652278743 1.6935536797533965 0.8426056181707403 0.09243154277561169 0.7395245990837742 0.28037506602296464 0.07034082941190153 0.3027219780165365 1.8246205835653215e-06 5.7388274301636555 0.7628556145255222 MS(ph)QPGSPSPK ddPTM_PC-9_Lapatinib_30min_R1 1 MSQPGSPSPK 10 0 Q14839-2;A0A2R8Y8C1;A0A0C4DGG9;A0A2R8Y521;A0A2R8Y212;F5GWX5;A0A2U3TZM0;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8YER1;Q14839;A0A2R8YDJ9;A0A2R8YD40;A0A2R8YE38;A0A2R8YDW2;A0A2R8YFD8;A0A2R8Y5M9;A0A2R8Y4X2;A0A2R8Y7I0;A0A2R8Y7M9 Q14839-2 CHD4 Chromodomain-helicase-DNA-binding protein 4 1 MS(0.512)QPGS(0.419)PS(0.068)PK 65.695 0.042392 85716000.0 45196.0 40610.0 46755.0 41718.0 41704.0 38235.0 40389.0 38115.0 42268.0 33763.0 True False 44551.4967520687 40515.970040070984 42910.98437951922 44786.08088716835 39251.052713218654 36599.77818013829 42480.14479510524 39885.962045648455 37507.33273822777 39598.889563630386 1.125069345201716 1.023159247305836 1.0836411033841422 1.1309933531141778 0.9912159948360976 0.9242627402803074 1.0727610108067562 1.0072495083872688 0.947181427346801 1.0 15.273172354210256 -6.280560802112529 23.88245199598811 0.9916142497521986 1.0853849604246286 0.5341270137817706 0.04576056949773302 394.09524686020416 492219.5230652702 0.014442026972891294 0.016405096057906344 5.241302165731359e-07 6.280560802112529 0.09377071067243004 MS(ph)QPIMVQRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MSQPIMVQRR 10 1 Q8TB72-4;A0A0A0MR59 Q8TB72-4 PUM2 Pumilio homolog 2 1 MS(1)QPIMVQRR 53.683 0.036521 0.0 714.14 885.81 1111.1 1086.5 1059.2 1107.0 939.78 2168.9 2141.6 1048.1 True False 835.0297970920639 973.7473626856549 1137.5928378702151 1025.6269274805263 851.6573635308206 1048.9469712378757 850.7572349820044 2111.9686731395054 2172.916848490852 1238.1122332449643 0.6744378858962866 0.7864774586174338 0.9188123720324626 0.8283796088440739 0.6878676590560087 0.8472147702544656 0.6871406421308491 1.7057974361534687 1.7550241328250682 1.0 10.273926383549377 -7.758613516513655 24.99996005421963 1.5478081844452478 0.7830669829541967 0.7131178522388724 0.20558816601885588 33.74506522352871 298545.9964563331 0.09634356657500526 0.05244686827036523 1.743357616596754e-08 7.758613516513655 -0.7647412014910511 MS(ph)QSRR ddPTM_PC-9_Lapatinib_30min_R1 1 MSQSRR 6 1 P31645-2 P31645-2 1 MS(0.996)QS(0.004)RR 63.148 0.031386000000000004 2162500.0 5481.6 2823.7 4176.3 3022.7 3258.9 4473.5 3549.8 2585.2 4808.0 3785.7 True False 5403.431378797673 2817.1618961376093 3832.9407349841986 3244.999441431608 3067.2179092439146 4282.178833237834 3733.591274695204 2705.317829736596 4266.4724095154525 4440.053200871828 1.2169744672736533 0.634488320001311 0.8632645965214065 0.7308469729133955 0.6908065670568204 0.9644431360410287 0.8408888600618779 0.6092985167847521 0.9609056956069147 1.0 12.116361247763173 -4.746913468030806 24.99893756449113 0.7995117787016985 1.2169755471615 0.45164112396015577 0.13385362565149572 676.1830242116764 1163638.3737284194 0.0313793803810507 0.6801173266075616 1.7909626628234034e-05 4.746913468030806 0.4174637684598015 MS(ph)S(ph)LRARLPAT(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 MSSLRARLPATR 12 2 J3KPS0 J3KPS0 DNAJB12 3 MS(1)S(1)LRARLPAT(1)R;MS(1)S(1)LRARLPAT(1)R 73.296 0.018827 0.0 7438.700000000001 9363.0 10407.0 17809.7 16247.7 10578.9 4672.2 16648.0 10414.1 8667.1 True False 9804.051865428108 12389.406646555679 10268.996380186993 13703.948822122089 13991.987310716737 9917.399710655987 5088.016748749278 14075.434132981873 10964.568065193474 8363.667467059928 1.1722192332539636 1.4813365901204243 1.2278102184993784 1.6385095266035756 1.6729487830337337 1.1857716426095837 0.6083475662785842 1.6829260833740198 1.31097608894389 1.0 13.029919987292525 -6.9006776783635475 10.86415801130244 1.1632777573136015 1.4400809345850896 0.19075438275496104 0.28958246819157096 0.7064775520411147 71.8231078905079 0.10540725464124694 0.09297136979508598 1.2569625012244284e-07 6.9006776783635475 0.27680317727148807 MS(ph)S(ph)MQLAPQELARWR ddPTM_PC-9_AZD4547_30min_R2 1 MSSMQLAPQELARWR 15 1 H0YF46;E9PPM7;Q6ZMY3-4;Q6ZMY3-3;Q6ZMY3-2;Q6ZMY3 H0YF46 SPOCD1 SPOC domain-containing protein 1 2 MS(1)S(1)MQLAPQELARWR 90.476 0.002805 2029500.0 6745.3 5135.9 5780.9 8033.4 8633.9 6985.8 6107.2 5940.9 5806.1 6122.1 True False 8890.165089044092 6795.979237001522 5704.241488827043 6181.423744792758 7435.23201696223 6548.976821663933 6650.728968785925 5022.870413300815 6112.998592611927 5907.767142422213 1.5048265909477065 1.1503464969364277 0.9655494794075917 1.046321494360447 1.258551977035735 1.1085367218754023 1.1257601744369183 0.8502146906286855 1.0347392585459232 1.0 12.528397247343447 -4.786840010240549 3.3554222641713274 1.055455604534199 1.5613599409956722 0.6434608646124966 0.10163198220059394 0.20828703094594905 3.7440082718926067 0.027741970460628068 0.2724216231436006 1.633653658784155e-05 4.786840010240549 0.5059043364614733 MS(ph)S(ph)MQLAPQELARWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MSSMQLAPQELARWR 15 1 H0YF46;E9PPM7;Q6ZMY3-4;Q6ZMY3-3;Q6ZMY3-2;Q6ZMY3 H0YF46 SPOCD1 SPOC domain-containing protein 1 2 MS(1)S(1)MQLAPQELARWR 80.102 0.0067936 1465200.0 2103.5 3654.1 1037.4 3943.6 3581.0 3570.3 4776.9 4973.5 4317.8 3926.9 True False 2459.581003981231 4016.854898894402 1062.135550361409 3722.652877323706 2879.3287564235916 3383.0671828460613 4324.397450238924 4842.950894858836 4380.939656524933 4638.8158846767055 0.5302174229647503 0.8659224678787505 0.2289669555262879 0.8025006747132734 0.620703392418486 0.7292954208467876 0.9322201091281952 1.0440058444346638 0.9444090400303212 1.0 12.179540871195796 -7.162270793781907 1.7359698999016546 1.0029668304771224 0.6071809555840892 0.5437795703550208 0.161136048170086 0.28276972524015337 1.6767144414044524 0.07953855817881253 0.053136083255591854 6.88223037762376e-08 7.162270793781907 -0.3957858748930332 MS(ph)SHTETSSFLQTLTGR ddPTM_PC-9_AZD4547_30min_R2 3 MSSHTETSSFLQTLTGR 17 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 MS(0.826)S(0.173)HT(0.001)ETSSFLQTLTGR;MS(0.904)S(0.095)HT(0.001)ETSSFLQTLTGR;MS(0.499)S(0.499)HT(0.002)ETSSFLQTLTGR 99.669 0.0010876 12575500.0 31848.5 30092.300000000003 48653.0 84213.0 61618.5 57272.0 40411.8 61237.0 37778.4 50902.4 True False 41975.66051004707 39819.047488000375 48007.82943069453 64798.99392788014 53063.83488773178 53690.77278627172 44008.371911970025 51774.22873626925 39775.28909786783 49120.32246948473 0.8545477390976784 0.8106430390952211 0.977351674767988 1.3191890987306842 1.080282706219954 1.0930460161296034 0.895930028539808 1.0540286816812576 0.8097521982388785 1.0 15.584032411422024 -5.385998461922184 4.838360675740898 1.0437569630743917 0.835193143424011 0.2820549446300138 0.1266295820492427 0.2762605522467976 9.582771604545774 0.035106088527348006 0.07593368263144158 4.111511772164723e-06 5.385998461922184 -0.20856381965038073 MS(ph)SHTETSSFLQTLTGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MSSHTETSSFLQTLTGR 17 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 MS(0.829)S(0.17)HT(0.001)ETSSFLQTLTGR;MS(0.81)S(0.19)HTETSSFLQTLTGR 105.65 0.00062379 7749500.0 32699.0 30266.0 37985.0 34517.0 44827.0 41671.0 42019.0 39836.0 40203.0 29745.0 True False 38234.29486531128 33270.608458974304 38890.706458914705 32583.124395623865 36043.47114331202 39485.69940239705 38038.65612878423 38790.34720973093 40790.89281839641 35137.53303870956 1.0881325909587947 0.9468680804176394 1.1068137998211323 0.9273025616149088 1.025782632594167 1.1237470587049265 1.082564791525877 1.1039576161194131 1.1608923362223176 1.0 15.100725284676164 -6.691017956616001 6.496568389742668 1.0998534853428898 1.0139366505990295 0.2547388162298848 0.06386586204163013 0.25957367538045567 18.769108345393892 0.019929147156094316 0.01980891424443564 2.0369578546089362e-07 6.691017956616001 -0.08591683474386036 MS(ph)SHTETSSFLQTLTGR ddPTM_PC-9_Lapatinib_30min_R1 2 MSSHTETSSFLQTLTGR 17 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 MS(0.489)S(0.489)HT(0.019)ET(0.003)S(0.001)SFLQTLTGR;MS(0.783)S(0.213)HT(0.003)ETSSFLQTLTGR 74.726 0.0053433 4612100.0 10223.2 10212.0 10385.3 7299.200000000001 10264.9 7827.6 10322.5 9675.7 14396.0 7259.6 True False 10077.415293294724 10188.354741423413 9531.460722417301 7836.0075174174 9661.138763569876 7492.831795026816 10856.948541619598 10125.268344879465 12774.570883399421 8514.41218719104 1.1835714635069048 1.1966010709172183 1.1194502348331568 0.9203227827290037 1.1346806510147531 0.8800175079964916 1.2751260219645741 1.1891917048732705 1.500346777034979 1.0 13.055691218101215 -7.344330415793844 24.999813540167604 1.2569329269956038 1.0761289933270164 0.2306713408172929 0.14976068978161947 132.94429300223211 40093.76565226994 0.06124466595309141 0.04129113123370737 4.5255314172053585e-08 7.344330415793844 -0.18080393366858738 MS(ph)SPEDDSDTKR ddPTM_PC-9_Lapatinib_30min_R1 1 MSSPEDDSDTKR 12 1 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 1 MS(0.771)S(0.229)PEDDSDTKR 59.607 0.023607 1583700.0 14899.0 12833.0 16535.0 14964.0 16435.0 13681.0 14108.0 11580.0 16358.0 12179.0 True False 14686.53752785803 12803.28597695717 15175.556126945798 16064.502478440658 15468.325612453209 13095.895521968667 14838.443209025843 12118.049074868399 14515.589782623481 14284.12392250258 1.028172088644618 0.8963298026830638 1.0624072018192796 1.124640374558313 1.0829033475469287 0.9168147513294791 1.038806670225677 0.8483578790420712 1.0162044141717548 1.0 13.80212493480032 -6.7629786385030455 24.999985269073644 0.9592322324886965 1.0370408781145624 0.1996251534161665 0.07458623319369471 71.76690012375883 1165589.1887329733 0.02666263589010784 0.02477729616849318 1.7259227822872128e-07 6.7629786385030455 0.07780864562586587 MS(ph)SPPSSPQK ddPTM_PC-9_AZD4547_30min_R2 2 MSSPPSSPQK 10 0 A0A087X1M6;G5E9X3;Q9Y2H6-2;Q9Y2H6 A0A087X1M6 FNDC3A Fibronectin type-III domain-containing protein 3A 1 MS(0.553)S(0.446)PPSS(0.001)PQK;MS(0.498)S(0.498)PPSS(0.003)PQK 94.76700000000001 0.0054381 14448900.0 91157.0 97098.0 140824.0 122856.0 113558.0 78269.0 111621.0 121213.0 95824.0 89858.0 True False 120143.02981661157 128483.02964512048 138956.58174723282 94533.44730627858 97792.43185376233 73374.82705700352 121555.05276147055 102482.31604764101 100889.06101142688 86712.09877064644 1.3855394059183133 1.4817197538368687 1.6025051142490863 1.0901990454217885 1.1277830111392342 0.846189033563586 1.4018234419972206 1.1818687069114404 1.1634946269525608 1.0 16.403945683476792 -5.769087066840775 24.999089292023314 1.1246556986404852 1.48910127019432 0.5950783054478089 0.14125282122188426 118.89216741149949 388640.8775729685 0.0404593579418598 0.0613188422999041 1.7018172958874103e-06 5.769087066840775 0.36444557155383484 MS(ph)SRLGAVPAT(ph)S(ph)GPTTFK ddPTM_PC-9_AZD4547_30min_R2 2 MSSRLGAVPATSGPTTFK 18 1 G3XAG1;Q96ME7-3;Q96ME7 G3XAG1 ZNF512 Zinc finger protein 512 3 MS(0.935)S(0.309)RLGAVPAT(0.87)S(0.868)GPT(0.014)T(0.003)FK;MS(0.978)S(0.071)RLGAVPAT(0.978)S(0.973)GPT(0.001)TFK 77.795 0.010121 0.0 15976.300000000001 17196.800000000003 21774.2 24648.0 24116.0 22125.0 23793.0 23370.0 19403.5 21557.0 True False 21056.431072316293 22755.32929824721 21485.45988099046 18965.7844078039 20767.90967246101 20741.520252414113 25910.530906851527 19758.703489175045 20429.129396969653 20802.295991440136 1.012216684205471 1.0938854685853292 1.0328407926620906 0.9117159190316331 0.9983469940532874 0.9970784119670717 1.245561111019349 0.9498328212090379 0.9820612784942567 1.0 14.344455149870571 MS(ph)TRS(ph)S(ph)KAAS(ph)NDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MSTRSSKAASNDK 13 2 Q5FWF5-2;Q5FWF5 Q5FWF5-2 ESCO1 N-acetyltransferase ESCO1 4 MS(0.771)T(0.258)RS(0.986)S(0.986)KAAS(1)NDK 54.416000000000004 0.041851 0.0 12236.0 20836.0 13923.0 14462.0 19259.0 14046.0 22169.0 16035.0 15073.0 14209.0 True False 14307.313127983998 22904.460379673186 14254.977123271534 13651.74102643661 15485.337201888276 13309.40303343017 20068.991830339077 15614.098240486877 15293.41410968556 16784.979221617883 0.8523878962898671 1.3645808003249618 0.8492698701057739 0.813330826698559 0.9225711272817211 0.7929353297195976 1.195651872150763 0.9302423335965175 0.9111369104341046 1.0 14.034883130651794 -5.341197410026063 24.999998221176178 0.925005157149724 1.1085541215449937 0.17656577840891163 0.15681854936690945 149.29601560135887 46795.089382828 0.039663883843658966 0.08256696434836173 4.558296699340346e-06 5.341197410026063 0.1835489643952697 MS(ph)Y(ph)IAS(ph)TK ddPTM_PC-9_Lapatinib_30min_R1 1 MSYIASTK 8 0 Q9UI47 Q9UI47 CTNNA3 Catenin alpha-3 3 MS(0.998)Y(0.986)IAS(0.508)T(0.508)K 41.979 0.043024 0.0 12025.0 13421.0 12222.0 10050.0 12194.0 10534.0 9031.0 8468.1 8888.1 9795.7 True False 11853.52129488508 13389.92449908378 11217.154338284341 10789.1105258172 11476.772894326401 10083.485375953362 9498.580990977624 8861.558840318921 7887.0285821577145 11488.873693050205 1.0317391949443622 1.1654688576812842 0.9763493478973285 0.9390921002416187 0.998946737596121 0.8776739692118832 0.8267634621767546 0.7713165865579507 0.6864927575040448 1.0 13.48794975045798 -6.396104027599515 0.7857048673833044 0.7973083943334909 1.08734275387507 0.5413148933071108 0.08971743201984521 0.47829337832338453 0.6501167112100626 0.052256118396438296 0.0763936076709703 4.0169458045736675e-07 6.396104027599515 0.2900343595415791 MSAQESTPIMNGVTGPDGEDYS(ph)PWADRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MSAQESTPIMNGVTGPDGEDYSPWADRK 28 1 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L0Y9 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 MSAQESTPIMNGVTGPDGEDY(0.103)S(0.897)PWADRK 53.563 0.0018119 5513700.0 10920.0 11979.0 16031.0 17697.0 15753.0 15851.0 14894.0 18530.0 16210.0 10949.0 True False 12768.540320168777 13168.195953547 16413.23983790607 16705.494464448107 12666.312733856697 15019.745655909277 13483.132496777953 18043.607134157886 16447.040583692902 12933.96702776369 0.9872099018622968 1.0181095966365554 1.269002758602513 1.2915986586782355 0.9793060943071484 1.1612636419799365 1.0424591672327166 1.3950559094070663 1.2716160902829075 1.0 13.658877217226442 -7.740428156772793 24.98883474609865 1.2500021714155825 1.1140819392744516 0.11698239363033003 0.13796710896336079 418.4578175841837 497676.71911666135 0.06563686042782362 0.03784432018261216 1.8179077588757046e-08 7.740428156772793 -0.1359202321411308 MSCFSRPSMS(ph)PTPLDR ddPTM_PC-9_AZD4547_30min_R2 1 MSCFSRPSMSPTPLDR 16 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MSCFS(0.005)RPS(0.011)MS(0.934)PT(0.05)PLDR 76.176 0.0055166 37852000.0 35495.0 26341.0 39873.0 59581.0 51127.0 44330.0 31617.0 53528.0 33587.0 39984.0 True False 46781.67165813529 34855.21312367009 39344.25796744461 45845.520967273806 44028.89856625953 41558.038092181625 34430.85174975516 45256.47755107242 35362.3402507805 38584.17233018243 1.212457565703447 0.9033552106650901 1.0196994153653933 1.1881950084338389 1.141112946248635 1.0770747584411158 0.8923568828978523 1.1729285563985155 0.916498608501143 1.0 15.23572153834847 -7.035790146550152 24.86734529065146 1.006265157383932 1.0861949323080577 0.15391596547955622 0.10773269839097084 1325.2122861760156 920766.7973506834 0.04111260721593273 0.031857390069989354 9.208944454540251e-08 7.035790146550152 0.07992977492412567 MSCFSRPSMS(ph)PTPLDR ddPTM_PC-9_Lapatinib_30min_R1 2 MSCFSRPSMSPTPLDR 16 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MS(0.001)CFS(0.004)RPS(0.034)MS(0.929)PT(0.033)PLDR;MS(0.006)CFS(0.006)RPS(0.074)MS(0.781)PT(0.135)PLDR 62.739 0.017095 65320000.0 68276.0 44639.0 61926.0 45699.0 49618.0 45107.0 35996.0 40196.0 53686.0 35937.0 True False 67302.37171971521 44535.641138111976 56834.683321272794 49059.85690739507 46699.5667927413 43177.8787595527 37859.69675021932 42063.65290271243 47639.317341357426 42148.6625669575 1.5967854641365773 1.0566323680463767 1.348433849614683 1.1639718538982922 1.107972684033668 1.0244187153260245 0.8982419475368948 0.9979830993662011 1.130268778177183 1.0 15.363199232813354 -1.522878745280738 0.4162199561223671 1.0014731237894086 9.873663265896914 0.6285814380136008 0.11750538173667711 52.52350602977993 0.6777183221176025 0.0808245477262435 386.91366356986185 0.02999999999997234 1.522878745280738 8.872190142107506 MSDTGS(ph)PGMQR ddPTM_PC-9_AZD4547_30min_R2 2 MSDTGSPGMQR 11 0 A0A087WWA3;Q4R9M9;O60333-2;O60333;O60333-4;A0A0U1RQL3 A0A087WWA3 KIF1B;KIF1Bbeta Kinesin-like protein;Kinesin-like protein KIF1B 1 MS(0.009)DT(0.233)GS(0.758)PGMQR;MSDT(0.246)GS(0.754)PGMQR 64.945 0.02745 7220300.0 25900.9 26031.6 37591.9 48159.0 42860.9 43906.4 30442.2 49117.0 34068.2 39218.8 True False 34136.847427812274 34445.805624316854 37093.40684388889 37056.68659913293 36910.4038679874 41160.925867145575 33151.49682564431 41527.096246376175 35868.97550039125 37845.76174927368 0.9019992160276021 0.9101628301873966 0.9801204977622302 0.9791502373404891 0.9752850031799337 1.087596707389184 0.8759632596450655 1.0972720412259411 0.9477673018717777 1.0 15.207844125053297 -5.2735786149769455 1.4941410740124588 0.9987202115369499 0.8900552781833577 0.250748633720672 0.060205117216214125 0.7184336749184416 2.6038166883943457 0.016933152138924417 0.08744804206576463 5.326248010934619e-06 5.2735786149769455 -0.10866493335359217 MSDTGS(ph)PGMQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MSDTGSPGMQR 11 0 A0A087WWA3;Q4R9M9;O60333-2;O60333;O60333-4;A0A0U1RQL3 A0A087WWA3 KIF1B;KIF1Bbeta Kinesin-like protein;Kinesin-like protein KIF1B 1 MS(0.001)DT(0.212)GS(0.787)PGMQR;MSDT(0.221)GS(0.779)PGMQR 76.165 0.012503 59243000.0 17761.1 21332.1 22269.3 23982.1 26665.0 21836.6 24748.7 18027.7 20341.9 18332.2 True False 20767.703432284787 23449.8099090625 22800.284568790557 22638.460688017236 21440.184666304125 20691.450254862695 22404.323970928457 17554.491976927056 20639.361804406075 21655.682742384648 0.9589955523146864 1.082847868987588 1.0528545712468205 1.045381988521151 0.990048890231535 0.9554743898406514 1.0345701974603905 0.8106182652264888 0.9530690881433435 1.0 14.402458036763308 -6.900398489293627 1.1424591993700615 0.926945443835631 1.0391347876111028 0.2785936489498829 0.06206351470138333 0.5396427774769454 1.471410416486355 0.03424532203558401 0.027026186077482844 1.2577708076370995e-07 6.900398489293627 0.11218934377547174 MSDTGS(ph)PGMQR ddPTM_PC-9_Lapatinib_30min_R1 4 MSDTGSPGMQR 11 0 A0A087WWA3;Q4R9M9;O60333-2;O60333;O60333-4;A0A0U1RQL3 A0A087WWA3 KIF1B;KIF1Bbeta Kinesin-like protein;Kinesin-like protein KIF1B 1 MS(0.002)DT(0.242)GS(0.756)PGMQR;MSDT(0.197)GS(0.803)PGMQR;MSDT(0.163)GS(0.836)PGMQR;MSDT(0.227)GS(0.773)PGMQR 125.36 0.00040955 33057200.0 150179.5 146486.4 165391.6 129393.8 159011.9 146261.3 134497.1 140055.6 160891.9 115735.3 True False 148037.91279045292 146147.21974089753 151793.741078039 138909.85169706302 149659.13267142352 140006.04515074298 141460.7017386356 146563.0944741049 142770.55995518298 135739.9923974063 1.0905990944587793 1.0766703103461355 1.118268377632084 1.0233524346338276 1.1025426628378328 1.0314281198782371 1.0421446122118583 1.0797340701553289 1.0517943712358053 1.0 17.05048631187089 -14.52287873171434 0.06243129227019559 0.7577788400213249 1.166868594293839 0.424565149953686 0.02727380312066718 371.07303684864627 1.6803206868299148 13.567584010917242 2.096289775121086 3.0000000937105976e-15 14.52287873171434 0.40908975427251415 MSDYS(ph)PNSTGSVQNTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MSDYSPNSTGSVQNTSR 17 0 H7C1W4;Q93075 H7C1W4 TATDN2 Putative deoxyribonuclease TATDN2 1 MS(0.062)DYS(0.866)PNS(0.013)T(0.045)GS(0.013)VQNTSR 120.54 0.00072151 0.0 9944.6 9405.8 12251.0 14514.0 13949.0 15380.0 14944.0 17142.0 12353.0 11599.0 True False 11628.024365196923 10339.545663233353 12543.110302176221 13700.827635022879 11215.793583734345 14573.445725057385 13528.396134809289 16692.040663450338 12533.639255420007 13701.806882366518 0.84864897491451 0.7546118371103149 0.9154347605291768 0.9999285315176278 0.8185631048535987 1.0636148830715617 0.9873439503967613 1.2182364564583148 0.9147435344129773 1.0 13.742078536117853 -5.993146618726248 0.6516304420838177 1.052400290641665 0.7824911359649912 0.39884308488299125 0.09787886893390273 0.9708317593422476 0.7853032025463388 0.058514827577857045 0.159064688601041 1.015905663091598e-06 5.993146618726248 -0.26990915467667376 MSES(ph)PTPCSGSSFEETEALVNTAAK ddPTM_PC-9_AZD4547_30min_R2 2 MSESPTPCSGSSFEETEALVNTAAK 25 0 D6RAA5;Q4VXL8;E7EMZ9;E9PBC6;O95359-6;O95359-1;O95359-5;O95359-3;O95359;H0Y911;Q4VXL4;O95359-2 D6RAA5 TACC2 Transforming acidic coiled-coil-containing protein 2 1 MS(0.173)ES(0.768)PT(0.059)PCSGSSFEETEALVNTAAK;MS(0.159)ES(0.657)PT(0.182)PCS(0.001)GSSFEETEALVNTAAK 112.9 5.0487e-08 5704200.0 40586.0 32746.0 48941.0 64437.0 56457.0 49929.0 48611.0 54453.0 44312.0 47716.0 True False 53491.50375875696 43330.50411706847 48292.01036251867 49582.045191725934 48618.92006875647 46806.931737075 52937.284828014905 46038.54005545784 46654.24185525904 46045.47736362008 1.1617102660557905 0.941037135414809 1.0487894387793566 1.0768059759740933 1.0558891524744978 1.0165370068257027 1.1496739280162172 0.9998493379033199 1.0132209399596743 1.0 15.490771839763948 MSES(ph)PTPCSGSSFEETEALVNTAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MSESPTPCSGSSFEETEALVNTAAK 25 0 D6RAA5;Q4VXL8;E7EMZ9;E9PBC6;O95359-6;O95359-1;O95359-5;O95359-3;O95359;H0Y911;Q4VXL4;O95359-2 D6RAA5 TACC2 Transforming acidic coiled-coil-containing protein 2 1 MS(0.203)ES(0.58)PT(0.203)PCS(0.009)GS(0.003)S(0.001)FEET(0.001)EALVNTAAK 53.758 0.0061354999999999995 2642800.0 13057.0 13941.0 22268.0 16970.0 23278.0 21356.0 19180.0 20889.0 17818.0 16160.0 True False 15267.292212494855 15324.970347140716 22798.953571860282 16019.225917482323 18716.843002521186 20236.05376491064 17363.13154882509 20340.68588372499 18078.554541655783 19089.680077510387 0.7997667928694782 0.8027882230040676 1.1943077872069632 0.8391563322401943 0.9804691815957438 1.0600520114923664 0.9095559212268126 1.0655330943805819 0.9470328715961136 1.0 14.220505304477955 -5.0770177145888455 24.99954874274223 0.9946731095915086 0.8005181327466013 0.4300702379227914 0.09114835749785659 90.05988350421556 29232.377169842424 0.021632536523358798 0.05723437501285607 8.374951205500816e-06 5.0770177145888455 -0.19415497684490723 MSES(ph)PTPCSGSSFEETEALVNTAAK ddPTM_PC-9_Lapatinib_30min_R1 2 MSESPTPCSGSSFEETEALVNTAAK 25 0 D6RAA5;Q4VXL8;E7EMZ9;E9PBC6;O95359-6;O95359-1;O95359-5;O95359-3;O95359;H0Y911;Q4VXL4;O95359-2 D6RAA5 TACC2 Transforming acidic coiled-coil-containing protein 2 1 MS(0.114)ES(0.721)PT(0.165)PCSGSSFEETEALVNTAAK;MS(0.04)ES(0.479)PT(0.479)PCS(0.001)GSSFEETEALVNTAAK 135.06 1.0434000000000001e-08 9424000.0 93669.0 90189.0 111886.0 80044.0 96091.0 100235.0 87338.0 85520.0 100761.0 87412.0 True False 92333.26288320903 89980.17291169571 102687.16497244983 85930.70277895629 90439.11630217465 95948.18270919735 91859.93429188395 89493.57140610905 89412.2351196312 102521.04773083143 0.9006273826388276 0.877675120409794 1.0016203232925842 0.8381762055784582 0.8821516976652654 0.9358876526614213 0.8960104907731905 0.8729287632825802 0.8721354014483215 1.0 16.645560602115253 MSGGS(ph)TMSSGGGNTNNSNSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 MSGGSTMSSGGGNTNNSNSK 20 0 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 MS(0.331)GGS(0.554)T(0.084)MS(0.027)S(0.004)GGGNTNNSNSK;MS(0.273)GGS(0.323)T(0.323)MS(0.07)S(0.011)GGGNTNNSNSK;MS(0.006)GGS(0.426)T(0.426)MS(0.141)S(0.002)GGGNTNNSNSK 110.98 3.7051e-05 5565300.0 8103.030000000001 7499.54 6699.0599999999995 8283.86 8542.0 6026.8 9248.570000000002 6164.200000000001 6820.790000000001 6014.2300000000005 True False 9474.71293686239 8244.044768466796 6858.790996726528 7819.74218083648 6868.256419260074 5710.743998424957 8372.478495751688 6002.396281509776 6920.531150083079 7104.562290381514 1.3336096651147245 1.1603874287411016 0.9654065537594452 1.1006648771907046 0.9667388557573263 0.8038136291881665 1.178465069844871 0.8448650368842706 0.9740967658841441 1.0 12.794530052927016 -3.956243507215316 0.8018932469192239 0.9633035780878544 2.4154141112990923 0.5507457365026924 0.10248057218653327 5.956011881389511 1.1185457041593545 0.03605599545192123 10.524259322239752 0.00011060034782732435 3.956243507215316 1.452110533211238 MSGGST(ph)MSSGGGNTNNSNSK ddPTM_PC-9_AZD4547_30min_R2 1 MSGGSTMSSGGGNTNNSNSK 20 0 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 MS(0.061)GGS(0.08)T(0.564)MS(0.249)S(0.046)GGGNTNNSNSK 108.58 8.6399e-05 2485500.0 6634.0 4593.8 9990.9 10577.0 9108.1 9908.5 8043.6 11378.0 8148.7 8603.5 True False 8743.474004227897 6078.656013344813 9858.414138061902 8138.636063021016 7843.597532250045 9288.919928634816 8759.464817482065 9619.791540429342 8579.423646099236 8302.294083701594 1.0531395197614588 0.7321658269463074 1.1874325383649273 0.9802876146001791 0.9447506259321715 1.1188377374959637 1.0550655914102045 1.1586907719053405 1.0333798778510725 1.0 13.019294320624748 -6.760040712627196 24.999554542846628 1.0819798976484618 0.9774007927085222 0.14377036246193942 0.11318761606520748 68.60137716442786 1226171.2279275495 0.03742588263187905 0.03549415297854525 1.737637927482817e-07 6.760040712627196 -0.1045791049399396 MSGGSTMS(ph)SGGGNTNNSNSK ddPTM_PC-9_AZD4547_30min_R2 3 MSGGSTMSSGGGNTNNSNSK 20 0 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 MS(0.008)GGS(0.036)T(0.186)MS(0.639)S(0.131)GGGNTNNSNSK;MS(0.352)GGS(0.047)T(0.186)MS(0.405)S(0.009)GGGNTNNSNSK;MS(0.006)GGS(0.013)T(0.056)MS(0.727)S(0.199)GGGNTNNSNSK 107.15 6.0106000000000004e-05 3902600.0 9262.2 8931.3 10506.0 13025.0 15276.099999999999 12214.2 9085.7 13651.1 11991.05 11675.5 True False 12207.386934271888 11818.168063909281 10366.683575501544 10022.28748424399 13155.277199679957 11450.444143142897 9894.309698666864 11541.63616607093 12624.872422786239 11266.744298745618 1.0834884160485472 1.0489426005012874 0.9201135040098245 0.8895460142252293 1.1676201084233888 1.0163046075713045 0.8781871174415884 1.024398518332924 1.1205430857423317 1.0 13.459783066078012 MSGGSTMS(ph)SGGGNTNNSNSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MSGGSTMSSGGGNTNNSNSK 20 0 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 MS(0.119)GGS(0.252)T(0.208)MS(0.375)S(0.045)GGGNTNNSNSK;MS(0.022)GGS(0.022)T(0.086)MS(0.82)S(0.049)GGGNTNNSNSK 86.291 0.00045197 2337500.0 7877.5 8411.9 4232.24 7159.0 7973.900000000001 6627.2 7785.0 5961.9 5981.1 5918.4 True False 9211.005162282923 9246.977839689618 4333.152652459582 6757.904439791157 6411.4715361201 6279.657965481162 7047.548441480886 5805.406442155202 6068.562272370491 6991.359069971373 1.3174842073045805 1.3226295126803551 0.6197868839366198 0.96660811898749 0.9170565367838205 0.8982027532319085 1.0080369740628616 0.8303688001221446 0.8680089538578569 1.0 12.77135721707543 -5.235929900729972 24.99980462515282 0.8908742999869556 1.3200570392786304 0.7307114254111935 0.10478345283226766 365.7045174026645 358396.5826307469 0.025621604908219315 0.0677338364847671 5.808581660011676e-06 5.235929900729972 0.42918273929167483 MSGGSTMS(ph)SGGGNTNNSNSK ddPTM_PC-9_Lapatinib_30min_R1 2 MSGGSTMSSGGGNTNNSNSK 20 0 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 MS(0.01)GGS(0.058)T(0.274)MS(0.545)S(0.112)GGGNT(0.001)NNSNSK;MS(0.019)GGS(0.161)T(0.235)MS(0.569)S(0.016)GGGNTNNSNSK 93.348 0.00036712 1617770.0 6141.01 4971.08 7890.099999999999 5849.6 7692.2 9721.8 8563.4 10393.6 9933.3 5027.91 True False 6053.438071276691 4959.569769682243 7241.406434666765 6279.799097693558 7239.759919447069 9306.021276622687 9006.770950961996 10876.524599702265 8814.507151713779 5896.977544231045 1.026532325394169 0.8410358921129251 1.2279860963267466 1.0649182654319285 1.2277068829149018 1.5781001719646492 1.5273537813914912 1.8444236082164942 1.494749994484365 1.0 12.525759985030463 -6.558865640106966 2.316634612723852 1.5480168177462097 1.0343685434904748 0.47565782302949755 0.21743552407383676 0.23080090380809065 2.5046850909538376 0.07613544601379474 0.07992923645590592 2.761432042359367e-07 6.558865640106966 -0.5136482742557349 MSGGSTMSS(ph)GGGNTNNSNSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MSGGSTMSSGGGNTNNSNSK 20 0 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 MS(0.048)GGS(0.011)T(0.048)MS(0.386)S(0.506)GGGNT(0.001)NNSNSK 58.073 0.0090777 398930.0 1340.2 2464.3 2159.5 2676.3 2862.0 960.48 1059.5 2350.4 1282.6 1172.5 True False 1567.0693898434258 2708.93941800867 2210.9906699493554 2526.3555876816686 2301.2116450389035 910.1107379715938 959.1364898842645 2288.7044904546515 1301.355598559193 1385.0649684951072 1.1314049705163427 1.9558211922376258 1.5963082745148252 1.8239978955114213 1.6614467172173177 0.6570888432478673 0.692484837679766 1.6524167042802054 0.9395628567323699 1.0 10.435737934241537 -6.739927914028726 24.523130104850207 1.0105976459933255 1.660170597072847 0.49867338909774117 0.32267261402422304 166.2400791510404 189513.53788314576 0.10770842265512398 0.10760500342463333 1.8200029250565132e-07 6.739927914028726 0.6495729510795216 MSGMEAT(ph)VRPGIGARPPFHS(ph)LPLR ddPTM_PC-9_AZD4547_30min_R2 1 MSGMEATVRPGIGARPPFHSLPLR 24 2 E9PIF9 E9PIF9 MTFR1L 2 MS(0.232)GMEAT(0.768)VRPGIGARPPFHS(1)LPLR 55.668 0.043955 0.0 21271.0 16774.0 18047.0 21370.0 25811.0 26531.0 22876.0 23616.0 23299.0 21504.0 True False 28034.73553571476 22195.867466551837 17807.68498829967 16443.476663208752 22227.588180290746 24872.01237590052 24911.91968331589 19966.689841692685 24530.53757414878 20751.151505308182 1.3509966195631806 1.0696210020380843 0.858154063582661 0.7924127323248775 1.071149626304106 1.1985846843023729 1.2005078213102234 0.9621967164851151 1.1821289805471193 1.0 14.340903775040525 -6.514303453058707 24.758271172586532 1.114594091242349 1.0003056739208236 0.06437793096122191 0.157025037863002 945.6144372722694 2730153.275265854 0.053760779404051766 0.05638317957983601 3.0598247060098333e-07 6.514303453058707 -0.1142884173215255 MSGS(ph)ASSENR ddPTM_PC-9_AZD4547_30min_R2 3 MSGSASSENR 10 0 A0A5F9UY30;A0A5H1ZRP2;O43493;O43493-5;O43493-3;O43493-7;O43493-4;O43493-6 A0A5F9UY30 TGOLN2 Trans-Golgi network integral membrane protein 2 1 MSGS(0.563)AS(0.424)S(0.012)ENR;MSGS(0.788)AS(0.205)S(0.007)ENR;MS(0.022)GS(0.473)AS(0.473)S(0.031)ENR 97.163 0.0046243000000000005 11760600.0 45380.4 49233.0 47161.0 38690.0 44084.6 42725.1 53751.0 49632.9 58836.0 50854.0 True False 59810.42322904189 65146.60444621122 46535.614325549985 29770.618254541252 37964.21424558693 40053.49274288896 58534.73487051555 41963.275755578805 61945.95084392535 49073.616938752944 1.218789788893881 1.3275280794468116 0.9482817291341995 0.6066522117515184 0.7736176099057205 0.8161919834211183 1.192794387737319 0.8551086790270971 1.2623066060371688 1.0 15.582659987766219 -5.2957272992982 7.034523932241154 0.9138507800763429 1.273280191015634 0.3507188362022621 0.18454698566473826 0.21017362348212565 35.23077827867172 0.050569582078619175 0.10895504373030443 5.061423774292636e-06 5.2957272992982 0.35942941093929104 MSGS(ph)ASSENR ddPTM_PC-9_Lapatinib_30min_R1 2 MSGSASSENR 10 0 A0A5F9UY30;A0A5H1ZRP2;O43493;O43493-5;O43493-3;O43493-7;O43493-4;O43493-6 A0A5F9UY30 TGOLN2 Trans-Golgi network integral membrane protein 2 1 MS(0.029)GS(0.485)AS(0.485)S(0.002)ENR;MS(0.011)GS(0.487)AS(0.487)S(0.015)ENR 83.182 0.012235 11795100.0 22403.0 55501.0 29829.0 23496.0 34969.0 26612.0 36195.0 33702.0 42701.0 18987.8 True False 22083.529111792952 55372.49084447124 27376.5747632698 25223.974220358294 32912.192171699186 25473.866795601916 38068.99999650485 35267.9179551999 37891.56371853563 22269.815930346856 0.9916350086082187 2.4864368442765485 1.2293130239107193 1.1326530178449223 1.4778834398379588 1.1438741512402413 1.7094438551074238 1.5836645469144024 1.7014762868740723 1.0 14.442802013226421 -11.448157087387148 2.5531265771418528 0.675352833557066 1.5038943942521799 0.1170727717363399 0.4073030882011975 11801411.439407997 6889609.339374475 22895585.114281483 0.10233467468210714 3.563222258438531e-12 11.448157087387148 0.8285415606951139 MSGSASS(ph)ENR ddPTM_PC-9_AZD4547_30min_R2 1 MSGSASSENR 10 0 A0A5F9UY30;A0A5H1ZRP2;O43493;O43493-5;O43493-3;O43493-7;O43493-4;O43493-6 A0A5F9UY30 TGOLN2 Trans-Golgi network integral membrane protein 2 1 MSGS(0.312)AS(0.205)S(0.483)ENR 99.34299999999999 0.0038835999999999996 8149800.0 44691.0 53077.0 54165.0 44212.0 51072.0 45652.0 52178.0 50163.0 57363.0 55712.0 True False 58901.808369452694 70233.1022726942 53446.736709217694 34019.60646859081 43981.53436689038 42797.37322319594 56821.74091782028 42411.46098106499 60395.09107111446 53761.539837413016 1.0956123754562277 1.3063818946610326 0.994144454769202 0.6327870550485301 0.8180854659278813 0.7960592898310729 1.0569217527932049 0.7888810683125295 1.1233884158408185 1.0 15.714286839912866 -3.2264778106739014 8.467373403336053 0.9508393940480838 1.0621492206299092 0.0 0.19017273380237054 0.0 0.0 0.04696139540972206 0.0 0.0005936386780856215 3.2264778106739014 0.11130982658182542 MSKPGS(ph)PGSVIPAQAHGK ddPTM_PC-9_Lapatinib_30min_R1 1 MSKPGSPGSVIPAQAHGK 18 1 Q8IZD2-6;Q8IZD2-5;Q8IZD2-2;Q8IZD2-7;Q8IZD2 Q8IZD2-6 KMT2E Histone-lysine N-methyltransferase 2E 1 MS(0.312)KPGS(0.344)PGS(0.344)VIPAQAHGK 48.229 0.035482 5539200.0 49849.0 45020.0 42104.0 38427.0 46729.0 50371.0 35131.0 42772.0 50059.0 39608.0 True False 49138.144118812976 44915.75895602054 38642.37164614006 41253.04976871416 43980.49209274879 48216.74975053601 36949.91128269681 44759.3432668628 44420.828275360625 46454.19002565745 1.0577763618668872 0.9668828351374287 0.8318382394526137 0.8880372200210441 0.9467497349207381 1.037941889071902 0.7954053501371725 0.9635157397457892 0.9562286685189482 1.0 15.503521108700154 MSLRVLGSGTWPS(ph)APK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MSLRVLGSGTWPSAPK 16 1 Q9P0G3 Q9P0G3 KLK14 Kallikrein-14 1 MSLRVLGS(0.11)GT(0.11)WPS(0.78)APK 52.611999999999995 0.037953 28206000.0 110710.0 138770.0 80792.0 118500.0 103110.0 82363.0 108980.0 77319.0 69277.0 84733.0 True False 129451.01637782842 152546.1685010197 82718.38768536627 111860.82918218373 82906.33568132836 78043.73928822516 98656.62545312589 75289.4581762522 70290.04506579218 100094.42215394098 1.29328901243606 1.5240226699786545 0.8264035688037531 1.1175530741378028 0.828281275791991 0.7797011822316852 0.9856355961713449 0.752184353094723 0.7022373829951191 1.0 16.61100205545327 -5.265934507095624 24.998438210377916 0.8728337298930078 1.4086558596739183 0.7268502105389332 0.13110143929054688 170.41192863630008 947705.2973421315 0.03433976232646604 0.0755790299310907 5.420826319172164e-06 5.265934507095624 0.5358221297809105 MSNLENDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MSNLENDR 8 0 Q5VU97;A0A3B3ISH2;A0A0A0MQY7;Q5VU97-2 Q5VU97 CACHD1 VWFA and cache domain-containing protein 1 0 46.994 0.034125 2799700.0 8299.7 9039.5 8359.2 9524.5 12481.0 12082.0 10509.0 10285.0 10916.0 9738.9 False True 9704.675283452822 9936.88182002572 8558.515030442537 8990.873143845627 10035.43764560817 11448.398650854577 9513.511441428724 10015.029647858273 11075.625848956926 11504.485476910022 0.8435557855177883 0.8637397856661605 0.7439285353195352 0.7815102345855172 0.8723065160758131 0.9951247862263798 0.8269393238422296 0.8705325994768607 0.9627223982494624 1.0 13.489908841902475 -6.491367729005233 6.2035947692526285 0.9184008431607094 0.8092931329861477 0.48773816641304646 0.05863357493696308 0.18845685494367967 23.148973058249236 0.01915161760847173 0.02107159932326038 3.225761624522155e-07 6.491367729005233 -0.10910771017456167 MSPAS(ph)PIDDIER ddPTM_PC-9_AZD4547_30min_R2 1 MSPASPIDDIER 12 0 B4DWJ3;Q96CJ1-2;Q96CJ1 B4DWJ3 EAF2 ELL-associated factor 2 1 MS(0.006)PAS(0.994)PIDDIER 95.18299999999999 0.0041175 2428900.0 15526.0 14438.0 18362.0 22097.0 25443.0 20598.0 17508.0 24238.0 17356.0 15805.0 True False 20462.94503913815 19104.80114952161 18118.507882482336 17002.878045246784 21910.678628148347 19310.00380380682 19066.17808250983 20492.574033830773 18273.402727023742 15251.6717606676 1.3416853811337495 1.2526365272816067 1.18796864808014 1.114820611934185 1.4366083254331241 1.2660909641135352 1.250104144758703 1.3436280530688374 1.1981245737368187 1.0 13.896679767053627 -8.548004397808791 17.594667516309737 0.9999999956190659 1.2697067050011497 0.49522333034722044 0.08358288291784513 82.24850224672088 57597.11865834362 0.08221429944980387 0.021228449039631947 2.8313633243377723e-09 8.548004397808791 0.26970670938208374 MSPAS(ph)PIDDIER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MSPASPIDDIER 12 0 B4DWJ3;Q96CJ1-2;Q96CJ1 B4DWJ3 EAF2 ELL-associated factor 2 1 MS(0.32)PAS(0.68)PIDDIER 76.357 0.016505000000000002 2771400.0 18878.0 22556.0 23614.0 20799.0 29335.0 20251.0 22048.0 17086.0 15872.0 19162.0 True False 22073.672542504246 24795.210612589195 24177.047316593704 19633.699461267814 23587.01733305948 19189.00191015197 19959.45382630322 16637.51060411342 16104.097973126074 22635.91891369145 0.9751613189050997 1.095392270449939 1.0680833152291465 0.8673692257040323 1.0420172215227699 0.847723566395416 0.8817602635177599 0.7350048684814 0.7114399920996991 1.0 14.466326254074959 -6.802280067555121 1.0988457273707808 0.7991610245898837 1.029138041031146 0.42661135358903 0.09701380779361066 0.42289523470081375 1.082686825974232 0.05213098071616777 0.04525249256486815 1.5765942286955126e-07 6.802280067555121 0.22997701644126223 MSPAS(ph)PIDDIER ddPTM_PC-9_Lapatinib_30min_R1 2 MSPASPIDDIER 12 0 B4DWJ3;Q96CJ1-2;Q96CJ1 B4DWJ3 EAF2 ELL-associated factor 2 1 MS(0.11)PAS(0.89)PIDDIER;MS(0.027)PAS(0.973)PIDDIER 113.69 0.0017537 1893900.0 25288.0 25037.0 27691.0 27992.0 32985.0 28752.0 23910.9 25486.0 30357.0 24708.0 True False 24927.38848274875 24979.028364768696 25414.35287035113 30050.625058574635 31044.88715100512 27522.34398418558 25148.88940506776 26670.17260121726 26937.87498661823 28978.74487865947 0.8601955877359541 0.861977579407304 0.8769997795545235 1.0369884956854885 1.0712985424661094 0.9497424439680818 0.8678391528125812 0.9203356706058623 0.9295735581169294 1.0 14.822707490091403 -5.6172630031911535 8.560516558064108 0.963918903994991 0.8632043779995361 0.41416761063049534 0.05540865474409623 0.2961951888923327 23.768482055518124 0.0173641165963427 0.03013429588556083 2.413998505044107e-06 5.6172630031911535 -0.10071452599545494 MSPMGT(ph)ASGSNSPTSDSASVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MSPMGTASGSNSPTSDSASVQR 22 0 Q5QPB1;O76080 Q5QPB1 ZFAND5 AN1-type zinc finger protein 5 1 MS(0.029)PMGT(0.968)AS(0.002)GSNSPTSDSASVQR;MS(0.024)PMGT(0.974)AS(0.002)GSNSPTSDSASVQR 132.65 1.2275e-05 34836000.0 9052.7 11544.2 10319.3 11799.7 13461.099999999999 12556.4 12095.5 9358.7 12957.7 9256.0 True False 10585.143311024898 12690.231883040089 10565.351248163182 11138.601064143551 10823.494086314882 11897.920279721098 10949.726676163396 9113.044041362304 13147.181848940012 10934.03952954431 0.9680908215507473 1.1606169749753017 0.966280688817256 1.018708688042192 0.9898897893197908 1.0881541307375315 1.0014347073262995 0.8334562918616136 1.2024084798134929 1.0 13.416538875946287 MSPNETLFLES(ph)TNK ddPTM_PC-9_AZD4547_30min_R2 1 MSPNETLFLESTNK 14 0 Q9HB90;Q9NQL2 Q9HB90 RRAGC;RRAGD Ras-related GTP-binding protein C;Ras-related GTP-binding protein D 1 MSPNETLFLES(0.841)T(0.159)NK 118.21 0.0015405999999999998 0.0 19117.0 23446.0 25201.0 22275.0 23083.0 29604.0 21026.0 25594.0 28311.0 24353.0 True False 25195.808341698026 31024.460988480634 24866.818273959132 17139.84289531937 19878.323891583084 27752.857200111524 22897.273267240787 21639.035391610894 29807.46166194798 23500.4088824763 1.0721434025978138 1.3201668593781295 1.058144068825191 0.7293423268094772 0.8458714055143901 1.180952099127355 0.97433510122093 0.9207939955353974 1.2683805550368403 1.0 14.52039823793926 -5.513250436440025 24.824161120097695 0.9795563705253247 1.1944052554317313 0.21883568588339297 0.15463523163883525 573.5024663672033 1478629.2311484898 0.042197873555888124 0.07887452655612234 3.0672527433048497e-06 5.513250436440025 0.21484888490640652 MSPNETLFLES(ph)TNK ddPTM_PC-9_Lapatinib_30min_R1 2 MSPNETLFLESTNK 14 0 Q9HB90;Q9NQL2 Q9HB90 RRAGC;RRAGD Ras-related GTP-binding protein C;Ras-related GTP-binding protein D 1 MSPNETLFLES(0.764)T(0.236)NK;MSPNETLFLES(0.929)T(0.071)NK 153.23 1.2701e-08 3087300.0 49566.0 54193.0 52705.0 55409.0 55660.0 56886.0 55670.0 53473.0 53466.0 48189.0 True False 48859.17975070881 54067.519438107964 48371.79834718343 59483.962699005504 52386.188231770364 54453.11838774277 58552.32020459798 55957.55079278392 47444.096058060146 56518.40444219368 0.8644826447760282 0.9566356299638209 0.855859234254525 1.0524706648406001 0.9268872458236203 0.9634581677449289 1.0359867866490209 0.9900766192013897 0.8394450715003 1.0 15.786433117411207 -5.742282628768597 24.999476951688866 0.9725576294455622 0.8987568320845171 0.26232336880556406 0.06141806833577384 361.8061863136092 472151.9019173637 0.01631761370561401 0.028206665556717917 1.8101616980070963e-06 5.742282628768597 -0.07380079736104517 MSQPGS(ph)PSPK ddPTM_PC-9_AZD4547_30min_R2 4 MSQPGSPSPK 10 0 Q14839-2;A0A2R8Y8C1;A0A0C4DGG9;A0A2R8Y521;A0A2R8Y212;F5GWX5;A0A2U3TZM0;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8YER1;Q14839;A0A2R8YDJ9;A0A2R8YD40;A0A2R8YE38;A0A2R8YDW2;A0A2R8YFD8;A0A2R8Y5M9;A0A2R8Y4X2;A0A2R8Y7I0;A0A2R8Y7M9 Q14839-2 CHD4 Chromodomain-helicase-DNA-binding protein 4 1 MS(0.057)QPGS(0.887)PS(0.057)PK;MS(0.041)QPGS(0.954)PS(0.005)PK;MS(0.149)QPGS(0.54)PS(0.311)PK;MS(0.001)QPGS(0.992)PS(0.007)PK 87.21600000000001 0.0094828 183839900.0 185114.0 168381.0 198326.0 245207.0 216767.0 197559.0 195853.0 212692.0 190303.0 197794.0 True False 243976.40138960592 222806.86538008042 195696.06765609357 188678.3145603853 186672.64372078094 185205.60449928488 213283.53758246521 179825.33857593572 200362.02806872566 190869.2922638082 1.2782380994654512 1.1673269321506679 1.0252883810435787 0.9885210571201016 0.9780129716349192 0.9703268781617563 1.117432432702047 0.9421386564759292 1.0497342222645074 1.0 17.542225489896033 -5.057893481349944 2.0864627671290035 1.0052258111553165 1.2902994322030847 0.7902417902514545 0.045897915533586665 0.17517227948900368 1.246172181911538 0.01229770203356844 0.07616315819571624 8.751984072919315e-06 5.057893481349944 0.28507362104776823 MSQPGS(ph)PSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MSQPGSPSPK 10 0 Q14839-2;A0A2R8Y8C1;A0A0C4DGG9;A0A2R8Y521;A0A2R8Y212;F5GWX5;A0A2U3TZM0;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8YER1;Q14839;A0A2R8YDJ9;A0A2R8YD40;A0A2R8YE38;A0A2R8YDW2;A0A2R8YFD8;A0A2R8Y5M9;A0A2R8Y4X2;A0A2R8Y7I0;A0A2R8Y7M9 Q14839-2 CHD4 Chromodomain-helicase-DNA-binding protein 4 1 MS(0.006)QPGS(0.497)PS(0.497)PK 77.124 0.019546 2426800.0 25623.0 24562.0 21540.0 29212.0 32849.0 28779.0 27842.0 26892.0 23126.0 21108.0 True False 29960.46782268176 27000.35303539706 22053.59529090489 27575.34634658182 26412.47425851957 27269.778577465964 25204.604201375816 26186.113494429257 23464.17399990637 24934.71330916393 1.2015565389184073 1.082841928063154 0.8844535334119852 1.105901880830826 1.0592652071444728 1.0936471672783925 1.0108239019581067 1.0501870693177537 0.9410244147977785 1.0 14.605867995031915 -4.86043356176193 4.043192063560266 1.024726902646128 1.2039508714739549 0.42785495905809623 0.06417658679491296 0.21078890136296682 5.6979977187178905 0.016015865393155027 0.09043779278862694 1.3790068968900525e-05 4.86043356176193 0.17922396882782676 MSQPGS(ph)PSPK ddPTM_PC-9_Lapatinib_30min_R1 3 MSQPGSPSPK 10 0 Q14839-2;A0A2R8Y8C1;A0A0C4DGG9;A0A2R8Y521;A0A2R8Y212;F5GWX5;A0A2U3TZM0;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8YER1;Q14839;A0A2R8YDJ9;A0A2R8YD40;A0A2R8YE38;A0A2R8YDW2;A0A2R8YFD8;A0A2R8Y5M9;A0A2R8Y4X2;A0A2R8Y7I0;A0A2R8Y7M9 Q14839-2 CHD4 Chromodomain-helicase-DNA-binding protein 4 1 MS(0.012)QPGS(0.559)PS(0.429)PK;MS(0.278)QPGS(0.678)PS(0.045)PK;MS(0.019)QPGS(0.561)PS(0.42)PK 85.973 0.010182 355699000.0 592946.0 529230.0 538243.0 482558.0 506690.0 530200.0 493755.0 477791.0 514814.0 402556.0 True False 584490.4813070204 528004.600450795 493990.73821806425 518046.925086299 476887.4903908681 507524.581956566 519319.21793822973 499990.9141218008 456830.22608824633 472137.2682278476 1.2379672621500248 1.1183285793825253 1.0462862634679169 1.0972379431743906 1.010061104010811 1.0749513247737117 1.0999326951830728 1.0589948046221833 0.9675792546581723 1.0 18.84884684122833 -1.5228791695656811 0.8395017113631758 1.044518974601751 65.71475683626986 0.693750560178721 0.039854006513188434 365.7319715033671 1.064189262947326 0.013920124061480103 45136.07036389694 0.029999970691421098 1.5228791695656811 64.6702378616681 MSQPGSPS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 MSQPGSPSPK 10 0 Q14839-2;A0A2R8Y8C1;A0A0C4DGG9;A0A2R8Y521;A0A2R8Y212;F5GWX5;A0A2U3TZM0;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8YER1;Q14839;A0A2R8YDJ9;A0A2R8YD40;A0A2R8YE38;A0A2R8YDW2;A0A2R8YFD8;A0A2R8Y5M9;A0A2R8Y4X2;A0A2R8Y7I0;A0A2R8Y7M9 Q14839-2 CHD4 Chromodomain-helicase-DNA-binding protein 4 1 MSQPGS(0.007)PS(0.993)PK;MS(0.008)QPGS(0.014)PS(0.978)PK;MSQPGS(0.117)PS(0.883)PK;MSQPGS(0.018)PS(0.982)PK 132.03 0.00016013 101474000.0 959992.0 838473.0 1022942.0 1271907.0 1075245.0 1041236.0 966766.0 1017641.0 911627.0 1004776.0 True False 1265249.4869259493 1109493.0000168195 1009377.1207015711 978688.4919172609 925965.7918297102 976127.3483183115 1052806.3011260943 860387.9665138026 959813.7420965926 969599.098070014 1.3049202391425767 1.1442801485946759 1.041025226519636 1.0093743835625872 0.9549986109443007 1.0067329376247276 1.0858160895793985 0.8873646522840254 0.9899078330488351 1.0 19.887028831240123 -4.6589999643176725 1.0810246553319283 0.9862667960692922 1.5311686230153456 0.8198956368325224 0.046445521773501704 0.8762144123447779 0.7090286724230056 0.01499735132374777 0.5841274178717414 2.192805115514808e-05 4.6589999643176725 0.5449018269460534 MSQPGSPS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 MSQPGSPSPK 10 0 Q14839-2;A0A2R8Y8C1;A0A0C4DGG9;A0A2R8Y521;A0A2R8Y212;F5GWX5;A0A2U3TZM0;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8YER1;Q14839;A0A2R8YDJ9;A0A2R8YD40;A0A2R8YE38;A0A2R8YDW2;A0A2R8YFD8;A0A2R8Y5M9;A0A2R8Y4X2;A0A2R8Y7I0;A0A2R8Y7M9 Q14839-2 CHD4 Chromodomain-helicase-DNA-binding protein 4 1 MSQPGS(0.009)PS(0.991)PK;MSQPGS(0.05)PS(0.95)PK;MS(0.008)QPGS(0.341)PS(0.651)PK;MS(0.035)QPGS(0.315)PS(0.65)PK 134.49 0.00011159999999999999 663791200.0 265395.0 283336.0 262405.0 303302.0 324896.0 273110.0 324655.0 299793.0 276950.0 237767.0 True False 310321.1317098157 311463.7255776095 268661.73037650477 286308.97225835145 261234.96108545118 258787.63081732302 293901.3281013459 291923.75140694005 280999.8698120755 280872.2749374631 1.1048478593300441 1.1089158787458024 0.9565263443546465 1.0193564755442623 0.9300845416074469 0.9213712206907667 1.0463878222469047 1.0393469824386816 1.0004542807745649 1.0 18.09955469667856 -5.252046103420057 24.62428562753167 0.9891832159370227 1.1068818936790614 0.5790774216877212 0.04013614751333304 409.299343490395 1072962.0647032098 0.01117249944776562 0.02869125758386436 5.59698182434606e-06 5.252046103420057 0.11769867774203868 MSQPGSPS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 6 MSQPGSPSPK 10 0 Q14839-2;A0A2R8Y8C1;A0A0C4DGG9;A0A2R8Y521;A0A2R8Y212;F5GWX5;A0A2U3TZM0;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8YER1;Q14839;A0A2R8YDJ9;A0A2R8YD40;A0A2R8YE38;A0A2R8YDW2;A0A2R8YFD8;A0A2R8Y5M9;A0A2R8Y4X2;A0A2R8Y7I0;A0A2R8Y7M9 Q14839-2 CHD4 Chromodomain-helicase-DNA-binding protein 4 1 MSQPGS(0.035)PS(0.965)PK;MSQPGS(0.13)PS(0.87)PK;MSQPGS(0.004)PS(0.996)PK;MS(0.007)QPGS(0.325)PS(0.667)PK;MS(0.004)QPGS(0.01)PS(0.986)PK;MS(0.014)QPGS(0.323)PS(0.663)PK 158.86 0.00012626 660768700.0 1317951.0 1038660.0 1124422.0 1027873.0 1042003.0 1051514.0 1003300.0 944500.0 1074830.0 835004.0 True False 1299156.777057389 1036255.0465850815 1031976.363554437 1103466.209303809 980714.4321967182 1006543.1974188542 1055245.9648153982 988384.9180667723 953771.3269383312 979333.3288271084 1.3265726171224204 1.0581229251394364 1.0537539499348767 1.1267524312946313 1.0014102485118768 1.0277840728900072 1.0775146048375643 1.009242603078264 0.973898568407356 1.0 19.90144045785891 -2.4168662831124093 1.3438597080092973 1.033517673531268 199.98746175517059 0.8045312429078617 0.042779040136176893 418.91410759087444 1.4859199386033404 0.01256096296332535 256150.28164602717 0.003829426311019358 2.4168662831124093 198.95394408163932 MSRRSADAS(ph)QRSLAYNR ddPTM_PC-9_AZD4547_30min_R2 1 MSRRSADASQRSLAYNR 17 3 J3KNG8;Q8TF40;Q8TF40-2;Q8TF40-3;A0A087WX11 J3KNG8 FNIP1 Folliculin-interacting protein 1 1 MSRRSADAS(0.75)QRS(0.186)LAY(0.064)NR 71.279 0.0074164 7310600.0 0.0 0.0 0.0 0.0 0.0 0.0 748.97 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 815.6268790528553 0.0 0.0 0.0 0.0 MSS(ph)HTETSSFLQTLTGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MSSHTETSSFLQTLTGR 17 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 MS(0.317)S(0.663)HT(0.019)ETSSFLQTLTGR 86.455 0.0026967 4278100.0 11692.0 15127.0 21074.0 21160.0 28637.0 18805.0 25518.0 22205.0 23614.0 16017.0 True False 13671.22467247376 16628.70858913978 21576.484083590072 19974.473801645596 23025.785422424575 17818.832695689485 23100.750305678783 21622.142278142248 23959.31007670106 18920.755309497767 0.7225517400783219 0.8788607176158854 1.1403606109085505 1.0556911431341691 1.216959103681563 0.9417611720154141 1.2209211486437204 1.1427737383870955 1.2662977605695296 1.0 14.207682061224466 -5.054274741626561 2.2515032735385905 1.128726381773636 0.7069538376975452 0.6522101467502405 0.09702250990061047 0.2180436773809144 1.8701396172292621 0.02521423710935472 0.14536319542302403 8.825214266358077e-06 5.054274741626561 -0.42177254407609077 MSS(ph)PEDDSDTKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MSSPEDDSDTKR 12 1 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 1 MS(0.036)S(0.96)PEDDS(0.003)DTKR 114.24 0.0018257000000000002 0.0 9118.9 8487.1 13386.0 7903.4 12803.0 10702.0 9171.5 9535.9 8691.3 6424.2 True False 10662.549663515298 9329.643198710137 13705.1730066877 7460.598121168515 10294.34405710451 10140.768280205739 8302.70912409017 9285.592729121216 8818.393820175825 7588.856606060777 1.4050271624581416 1.2293872032394306 1.8059602016649225 0.9830991028622376 1.356507915682979 1.3362709043819458 1.0940658856907746 1.2235825778688918 1.1620187701442517 1.0 12.88966681944277 -7.297411366009785 0.28910617484557144 0.9832162285418359 1.4821288997800186 0.2815082204270257 0.19290197420235186 2.6796158788797033 0.6396605024043363 0.3160593417188121 0.48592516818389075 5.041835060561279e-08 7.297411366009785 0.4989126712381827 MSS(ph)PLADAK ddPTM_PC-9_Lapatinib_30min_R1 1 MSSPLADAK 9 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 MS(0.189)S(0.811)PLADAK 89.82700000000001 0.0090455 5804700.0 94980.0 75645.0 101650.0 81663.0 82203.0 83099.0 76748.0 67240.0 85652.0 65865.0 True False 93625.56778280124 75469.84865011481 93292.72938034737 87668.76943978225 77367.9811573162 79545.04948323022 80721.63590915185 70364.21587168823 76004.96980445443 77249.67749040424 1.2119865198716353 0.9769600482732046 1.2076779141496865 1.1348755397803731 1.0015314454474797 1.0297136773562725 1.0449446331886485 0.9108674386430764 0.9838872118772998 1.0 16.237241289473054 -6.2738499856461445 8.141959678317276 0.9947743663328388 1.1271592827112906 0.48987816914160054 0.06874983381233332 0.1576007940493689 77.5618076588697 0.02089641718670624 0.02460056093386575 5.322920922833847e-07 6.2738499856461445 0.13238491637845184 MSS(ph)PPSSPQK ddPTM_PC-9_AZD4547_30min_R2 1 MSSPPSSPQK 10 0 A0A087X1M6;G5E9X3;Q9Y2H6-2;Q9Y2H6 A0A087X1M6 FNDC3A Fibronectin type-III domain-containing protein 3A 1 MS(0.263)S(0.733)PPSS(0.005)PQK 119.74 0.00067285 11900000.0 80429.0 84663.0 116720.0 91857.0 105660.0 58239.0 94329.0 98694.0 80615.0 77177.0 True False 106003.74897287409 112028.65907479895 115172.21653650678 70680.7878265029 90990.93282435872 54597.3061234055 102724.09826051358 83443.11006250072 84876.1443212157 74475.05672085048 1.423345662833133 1.5042440248781273 1.5464535591855746 0.9490531587163556 1.221763860689808 0.7330951935766719 1.3793087616642838 1.1204168715878198 1.139658673095757 1.0 16.184469696793755 -5.754143207739165 24.99998540316172 1.0868530870243343 1.492637476316645 0.5732489875210259 0.16344892547320314 119.58655536760723 409752.78492906503 0.04332633057196569 0.07313256675059801 1.7613951341073565e-06 5.754143207739165 0.40578438929231075 MSS(ph)PPSSPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MSSPPSSPQK 10 0 A0A087X1M6;G5E9X3;Q9Y2H6-2;Q9Y2H6 A0A087X1M6 FNDC3A Fibronectin type-III domain-containing protein 3A 1 MS(0.03)S(0.965)PPSS(0.005)PQK 67.385 0.038512 3429400.0 30426.0 37182.0 37542.0 32683.0 48692.0 30636.0 28241.0 25785.0 24276.0 22987.0 True False 35576.52085910763 40873.183232722644 38437.14365882787 30851.87746971563 39151.15213844665 29029.394228404308 25565.80803286599 25108.171071465797 24630.990574320113 27154.36113500812 1.310158640161909 1.5052161613932378 1.415505357232422 1.1361665743607046 1.4417997883946512 1.0690509006665174 0.9414991538838259 0.9246459876787777 0.9070731015124193 1.0 14.728896300694169 -6.914393821178965 3.7679633911776884 0.9424508160135013 1.3600045622104564 0.8139638994851184 0.09525224950350603 0.09881282669423883 2.7318335764919617 0.03668226538244334 0.03176657185226874 1.2178847119319174e-07 6.914393821178965 0.41755374619695507 MSS(ph)PPSSPQK ddPTM_PC-9_Lapatinib_30min_R1 3 MSSPPSSPQK 10 0 A0A087X1M6;G5E9X3;Q9Y2H6-2;Q9Y2H6 A0A087X1M6 FNDC3A Fibronectin type-III domain-containing protein 3A 1 MS(0.006)S(0.994)PPSSPQK;MS(0.225)S(0.533)PPS(0.003)S(0.238)PQK;MS(0.338)S(0.661)PPSSPQK 115.0 0.0010218 17536800.0 197005.0 215529.0 98907.0 61442.0 89932.0 101085.0 96535.0 84664.0 146227.0 44183.9 True False 194195.67257370797 215029.95584256196 90775.24825206098 65960.64964450349 84642.37657311485 96761.83019064418 101533.10995061725 88597.79852112781 129757.37542142575 51821.02824365399 3.7474299363692998 4.1494729674510955 1.7517068134049871 1.272854898485752 1.633359650355455 1.867230996183362 1.9593032672610273 1.7096881618125266 2.5039521564745457 1.0 15.66125002160746 -5.264915569808205 24.816803907260102 1.7334543898499524 3.948451585246262 0.8416687659844868 0.3878678104373483 85.9032732206702 613275.629621692 0.09896325692239875 0.22017462456199308 5.433559538070228e-06 5.264915569808205 2.2149971953963097 MSSPLASSHNS(ph)QTSMHK ddPTM_PC-9_AZD4547_30min_R2 2 MSSPLASSHNSQTSMHK 17 0 A0A3B3IRI0;Q5TC84 A0A3B3IRI0 OGFRL1 Opioid growth factor receptor-like protein 1 1 MSSPLAS(0.021)S(0.006)HNS(0.324)QT(0.324)S(0.324)MHK;MSSPLAS(0.01)S(0.01)HNS(0.327)QT(0.327)S(0.327)MHK 59.708999999999996 0.022685 34517000.0 1210.7 3066.3 97115.0 168911.0 99717.0 40519.0 8979.4 134849.0 28786.0 31787.0 True False 1595.6774158755995 4057.4215102353596 95827.19164618629 129971.17859893557 85873.01579071119 37985.340524635816 9778.549204597251 114011.18557174849 30307.569192216266 30674.146805209803 0.05202027055580839 0.13227495897444924 3.1240377199313225 4.237157089463392 2.7995241835422857 1.2383503530140325 0.3187879769466458 3.7168494464003947 0.9880492971712819 1.0 14.904735595743704 -5.2452751894808305 23.415810274586214 2.2706762739894133 0.0921462074464651 0.3132939345596797 1.2290201651722341 428.3324194389646 620484.9955980557 0.32791591679103727 0.8603284426961774 5.6849259295470324e-06 5.2452751894808305 -2.1785300665429483 MSSPLASSHNS(ph)QTSMHK ddPTM_PC-9_Lapatinib_30min_R1 2 MSSPLASSHNSQTSMHK 17 0 A0A3B3IRI0;Q5TC84 A0A3B3IRI0 OGFRL1 Opioid growth factor receptor-like protein 1 1 MSSPLAS(0.098)S(0.027)HNS(0.636)QT(0.12)S(0.12)MHK;MSSPLAS(0.387)S(0.083)HNS(0.434)QT(0.076)S(0.02)MHK 65.038 0.013165999999999999 33433000.0 7936.1 4016.9 191323.0 17143.9 35948.0 78929.0 18129.5 15280.4 156907.0 24246.0 True False 7822.929758697501 4007.5991148475996 175593.16146813706 18404.719596373878 33833.609316487265 75553.39066248554 19068.156801675228 15990.383167842747 139234.48135604002 28436.88879423579 0.2750979481371121 0.1409295912730069 6.174837294568248 0.6472128413747058 1.1897788665033355 2.6568796329716755 0.670543002775338 0.5623112740478144 4.896262821278223 1.0 14.79547601164261 -8.233127966781037 24.973947814939805 2.948135176853597 1.6144318659315073 0.07885631634440415 1.9118886622771483 1752.1602609498566 1545613.4692850893 1.2783508995907777 0.482958885059507 5.846177985552994e-09 8.233127966781037 -1.3337033109220895 MSTSQNS(ph)IPFEHHGK ddPTM_PC-9_AZD4547_30min_R2 1 MSTSQNSIPFEHHGK 15 0 P48730-2 P48730-2 CSNK1D Casein kinase I isoform delta 1 MST(0.001)S(0.003)QNS(0.995)IPFEHHGK 70.335 0.0093589 7387600.0 13292.0 13226.0 22601.0 28627.0 25697.0 21293.0 18628.0 25720.0 17898.0 22859.0 True False 17518.579509224797 17501.045851473395 22301.295972768945 22027.487432741083 22129.415112507482 19961.545343939164 20285.855912782343 21745.564986802834 18844.051740508818 22058.713367738088 0.7941795705476888 0.7933847074267487 1.010997133014369 0.9985844172107212 1.003205161769444 0.9049279081314809 0.9196300606748609 0.9858038691688497 0.854267945113659 1.0 14.42906102396392 -5.249941342283385 24.589099085654247 0.958728603044621 0.7937820981373948 0.6465257857459812 0.049061804756794024 365.13768154568027 780859.6300611479 0.012760272810857037 0.03310323560031575 5.624172826044134e-06 5.249941342283385 -0.1649465049072263 MSTSQNS(ph)IPFEHHGK ddPTM_PC-9_Lapatinib_30min_R1 2 MSTSQNSIPFEHHGK 15 0 P48730-2 P48730-2 CSNK1D Casein kinase I isoform delta 1 MS(0.007)T(0.006)S(0.019)QNS(0.969)IPFEHHGK;MS(0.054)T(0.012)S(0.048)QNS(0.886)IPFEHHGK 57.794 0.023949 15754300.0 56198.0 41702.0 54002.0 42704.0 44967.0 41782.0 40125.0 42674.0 50861.0 35465.0 True False 55396.60621454899 41605.44158116324 49562.16401374822 45844.59461636794 42322.12946852348 39995.081258599144 42202.476166867134 44656.7898290962 45132.49858992626 41595.07799585796 1.3318067637729971 1.0002491541260319 1.1915391532306687 1.1021639296104493 1.0174792669637 0.9615339887710238 1.0146026453194692 1.0736075511997627 1.0850442111064333 1.0 15.344125201880164 -3.1752950950978853 2.0121358446185025 1.0516279296079614 145.9633021161216 0.6135493304936126 0.0655943869654216 526.6249876859016 5.112346053026711 0.018550177358106296 350659.95849589095 0.0006678899444425819 3.1752950950978853 144.91167418651364 MSVNS(ph)GSSSSK ddPTM_PC-9_AZD4547_30min_R2 1 MSVNSGSSSSK 11 0 Q68DW7;Q8WVM7-2;Q8WVM7 Q68DW7 DKFZp781D1416;STAG1 Cohesin subunit SA-1 1 MS(0.001)VNS(0.306)GS(0.306)S(0.103)S(0.103)S(0.183)K 64.53399999999999 0.041343 2139900.0 10068.0 9464.5 12543.0 11578.0 11627.0 10145.0 10630.0 13620.0 10292.0 9538.5 True False 13269.414572590678 12523.714536614987 12376.671624549386 8908.870978316849 10012.791746628971 9510.631546248193 11576.04940696136 11515.341956464026 10836.014108465568 9204.560018293447 1.4416131293857182 1.3605989326730386 1.3446239255273016 0.9678758094478241 1.0878077525410468 1.0332521627700237 1.257642883956945 1.251047517054379 1.1772441145399362 1.0 13.16813304647662 -5.623774771629242 7.031111968772388 1.123571546615401 1.3890540207844633 0.6337016248498044 0.09476994308592097 0.15444312283265021 9.324320649258185 0.02794900624122845 0.048673634327777326 2.3780732534830277e-06 5.623774771629242 0.26548247416906223 MSVNS(ph)GSSSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MSVNSGSSSSK 11 0 Q68DW7;Q8WVM7-2;Q8WVM7 Q68DW7 DKFZp781D1416;STAG1 Cohesin subunit SA-1 1 MS(0.002)VNS(0.754)GS(0.068)S(0.036)S(0.104)S(0.036)K;MS(0.002)VNS(0.737)GS(0.143)S(0.05)S(0.05)S(0.017)K 64.53399999999999 0.041343 3001100.0 20477.7 27120.2 21900.2 24884.2 27109.1 20655.0 26563.0 17887.0 20054.1 16585.2 True False 23944.17015698904 29812.514224842238 22422.383824971002 23490.018949664907 21797.26645930264 19571.815438950613 24046.760340533954 17417.48520284307 20347.35327387018 19591.965471629028 1.2221423211296694 1.5216704147428959 1.1444683208247115 1.1989618389069039 1.1125614982767855 0.9989715155068237 1.2273786606737278 0.8890116322461467 1.0385559990566042 1.0 14.257974515997958 -5.852051531062422 0.7712616122046846 1.0180856385627222 1.3929783493219194 0.5269728478588731 0.11443978244972496 0.6662110236114454 0.7321468300047953 0.05480485981989559 0.16868099181274568 1.4058806999418243e-06 5.852051531062422 0.3748927107591973 MSVNS(ph)GSSSSK ddPTM_PC-9_Lapatinib_30min_R1 1 MSVNSGSSSSK 11 0 Q68DW7;Q8WVM7-2;Q8WVM7 Q68DW7 DKFZp781D1416;STAG1 Cohesin subunit SA-1 1 MSVNS(0.686)GS(0.096)S(0.045)S(0.045)S(0.128)K 84.89200000000001 0.010357 1595600.0 9210.4 11258.0 11133.0 9992.4 10380.0 9876.8 9855.4 12276.0 11314.0 7513.7 True False 9079.058007019506 11231.932792689458 10217.687714622776 10727.274429669234 9769.468807865185 9454.392287945328 10365.66438915745 12846.38777574132 10039.698178298217 8812.433033624073 1.0302555460425196 1.2745552505004827 1.1594627358456986 1.2172886181079656 1.1086006294277093 1.0728469937725305 1.1762545428268198 1.457757208108769 1.1392651881712441 1.0 13.105324673948763 -7.538904159717663 24.999616727288128 1.2425078463445236 1.149918211042495 0.0023136744993281777 0.12567096702499733 580.2946477425606 905247.0850337556 0.05619525262810005 0.03245492427643853 2.8913178691668542e-08 7.538904159717663 -0.09258963530202857 MSVNSGSS(ph)SSK ddPTM_PC-9_AZD4547_30min_R2 1 MSVNSGSSSSK 11 0 Q68DW7;Q8WVM7-2;Q8WVM7 Q68DW7 DKFZp781D1416;STAG1 Cohesin subunit SA-1 1 MS(0.109)VNS(0.152)GS(0.135)S(0.314)S(0.253)S(0.037)K 72.49600000000001 0.023854 2626100.0 8478.4 12857.0 11338.0 12636.0 8667.2 10328.0 12484.0 12357.0 10919.0 10726.0 True False 11174.354838324662 17012.773817661673 11187.650711882401 9722.9654242539 7463.90888676207 9682.18852731901 13595.051815287457 10447.509585611298 11496.1560484197 10350.486004740314 1.079597115846254 1.6436690808402779 1.0808816809914705 0.9393728390919013 0.721116755613577 0.9354332272788699 1.3134698997768024 1.0093738188551291 1.110687560289893 1.0 13.337410890285366 -5.48161595558242 13.550839669736472 1.0033797966140057 1.3618851192639934 0.3587665999733095 0.18846565055048317 2.816056589769146 922.7802702677358 0.05026027448055017 0.10421176561257929 3.2990131329342124e-06 5.48161595558242 0.3585053226499877 MSVQPT(ph)VSLGGFEITPPVVLR ddPTM_PC-9_AZD4547_30min_R2 1 MSVQPTVSLGGFEITPPVVLR 21 0 P06748;P06748-3;P06748-2;E5RI98 P06748;E5RI98 NPM1 Nucleophosmin 1 MS(0.001)VQPT(0.94)VS(0.056)LGGFEIT(0.003)PPVVLR 101.61 0.00040205 9165900.0 2335.5 3485.6 4941.9 6950.5 4783.1 3989.6 3228.0 4911.3 3135.9 3700.2 True False 3078.140418582194 4612.252035376959 4876.367177019901 5348.16960915454 4119.049127315818 3740.1296813121526 3515.2857465353986 4152.371435446531 3301.657271933264 3570.6571242532236 0.8620655278476127 1.291709585904745 1.3656778030849872 1.497811025547033 1.1535829355716383 1.047462568138455 0.9844926645737777 1.162915197665463 0.9246637683319372 1.0 11.801973889073576 -6.578531391289769 4.371109552313787 1.0338127742369612 1.2714953484674052 0.30663825471038053 0.16177347652360632 0.26631879448989654 10.594186306466073 0.056096838430838084 0.05691378194693218 2.6391775527727926e-07 6.578531391289769 0.23768257423044403 MSVQPTVS(ph)LGGFEITPPVVLR ddPTM_PC-9_AZD4547_30min_R2 1 MSVQPTVSLGGFEITPPVVLR 21 0 P06748;P06748-3;P06748-2;E5RI98 P06748;E5RI98 NPM1 Nucleophosmin 1 MSVQPT(0.135)VS(0.865)LGGFEITPPVVLR 244.73 3.5379999999999995e-61 10792000.0 30272.0 22477.0 31900.0 49324.0 39452.0 35156.0 30680.0 41169.0 31629.0 37850.0 True False 39897.86630328413 29742.25068830844 31476.98515691028 37953.1138482035 33974.770791090246 32957.689762434864 33410.460564964655 34807.27701950571 33300.84436811674 36524.883020643356 1.0923475451169662 0.8143010525591152 0.861795645974278 1.0391029541902415 0.9301815086413331 0.9023352585087716 0.9147314871913902 0.9529743599680558 0.9117303496713615 1.0 15.156592032022221 -11.189248190521955 2.771981014438812 1.0081305073777966 0.9315859631536109 0.05851573858464276 0.07617347755821065 43700647.79961527 40705362.349769264 2522184.310075091 0.018133893300082866 6.4677289247325676e-12 11.189248190521955 -0.07654454422418577 MSWFVDLAGK ddPTM_PC-9_AZD4547_30min_R2 1 MSWFVDLAGK 10 0 Q8TBA6-2;Q8TBA6 Q8TBA6-2 GOLGA5 Golgin subfamily A member 5 0 100.19 0.018818 19958000.0 37249.0 38030.0 54718.0 64515.0 55623.0 55820.0 40500.0 49301.0 43011.0 47011.0 False True 49093.40717266886 50322.45378281664 53992.40356789395 49642.06349681387 47900.70657286862 52329.566575808225 44104.42154110394 41682.66327427554 45284.47365130321 45365.15919903473 1.0821830682281275 1.1092753705995457 1.1901733515583648 1.0942772906188796 1.0558919536181819 1.1535188567556418 0.9722091208277384 0.9188254601157104 0.9982214203773094 1.0 15.469297101126028 -7.273236582644121 23.767252797869833 0.9655494219815863 1.113889891009649 0.7430799498216428 0.040800044112736376 194.3343942322491 391513.7317195241 0.017252091393410038 0.011751193549032871 5.3304443953320624e-08 7.273236582644121 0.14834046902806275 MSYLTAMGADYLS(ph)CDSR ddPTM_PC-9_AZD4547_30min_R2 6 MSYLTAMGADYLSCDSR 17 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 MSYLTAMGADYLS(0.998)CDS(0.002)R;MSYLTAMGADYLS(0.987)CDS(0.012)R;MSYLTAMGADYLS(0.99)CDS(0.01)R;MSYLTAMGADYLS(0.969)CDS(0.03)R;MS(0.001)YLT(0.003)AMGADY(0.019)LS(0.966)CDS(0.012)R;MSYLTAMGADYLS(1)CDSR 170.47 1.3835e-05 52862000.0 163336.0 165270.0 229797.0 319734.0 283412.0 270543.0 207412.0 265874.0 199323.0 232092.0 True False 215273.45040014607 218690.29546900088 226749.74163330748 246024.2661410571 244065.13584721868 253625.90344175696 225871.26618971516 224789.2824767197 209858.80685403044 223966.5297233068 0.9611858105141855 0.9764418627157179 1.0124269100094516 1.0984867535564395 1.0897393291253927 1.1324277058500305 1.008504558555073 1.0036735522688562 0.9370096822650003 1.0 17.772923621853018 -7.758683582679947 2.764086794545788 0.9720075531530075 1.0457517167087953 0.22776049577836543 0.05325385594887653 0.43979063342117913 6.771625230639038 0.03725500418403294 0.01688304091184219 1.743076377629124e-08 7.758683582679947 0.07374416355578783 MSYLTAMGADYLS(ph)CDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 MSYLTAMGADYLSCDSR 17 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 MSYLT(0.001)AMGADYLS(0.982)CDS(0.018)R;MSYLTAMGADYLS(0.974)CDS(0.026)R;MSYLTAMGADYLS(0.992)CDS(0.008)R 84.895 0.0019889 61110000.0 100872.0 109392.0 131373.0 126860.0 161059.0 133230.0 128861.0 122087.0 127632.0 99655.0 True False 117947.63728718569 120251.71481345787 134505.43055487666 119752.44548566926 129500.64512170521 126243.18426198945 116654.35320715075 118882.34561186915 129498.37654397824 117721.66263145402 1.001919567313954 1.0214918148915768 1.1425716180714065 1.0172507150240726 1.1000579012133658 1.0723870309002803 0.9909336191789556 1.0098595530717982 1.100038630522855 1.0 16.845020297747013 -9.558704107023976 8.153302846024523 1.0000000007350824 1.0507083412195497 0.09014130711164181 0.04834530717783845 8992203.156803902 3514068.880425489 0.047029115496769254 0.011757278947342421 2.7624593305594957e-10 9.558704107023976 0.05070834048446726 MT(ph)ALAQDFAVGLGPR ddPTM_PC-9_AZD4547_30min_R2 1 MTALAQDFAVGLGPR 15 0 P50416-2;P50416 P50416-2 CPT1A Carnitine O-palmitoyltransferase 1, liver isoform 1 MT(1)ALAQDFAVGLGPR 62.525 0.042722 8104400.0 48326.0 30999.0 48604.0 60588.0 58527.0 49473.0 32911.0 39844.0 27655.0 35009.0 True False 63692.66275675575 41018.82053151545 47959.47920271059 46620.372675268714 50401.536299557374 46379.445489160855 35840.01524294499 33687.025324034694 29116.78684119853 33783.345565910255 1.8853272726495767 1.2141728370711244 1.41961899863183 1.3799809312643065 1.4919048263359693 1.3728493940505686 1.0608782121066795 0.9971488838579459 0.8618680700048663 1.0 15.044024584904529 -7.306941006246568 2.1106781886573542 0.9448648638512229 1.4574375926781133 0.684042499609989 0.16229740978310833 0.19396464136871813 1.687630057871467 0.08013306156756152 0.049761648015103584 4.9324080031602446e-08 7.306941006246568 0.5125727288268904 MT(ph)CTCRQDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MTCTCRQDSK 10 1 Q58F21-2 Q58F21-2 1 MT(0.884)CT(0.116)CRQDSK 64.84100000000001 0.032579000000000004 1009600.0 2347.7 3511.5 3881.8 5176.9 3446.8 3067.1 3852.1 4894.4 4257.5 3584.2 True False 2745.119240811377 3860.0985133049708 3974.356833808478 4886.855076736249 2771.4242830608314 2906.2558766790335 3487.2012012111145 4765.927186045458 4319.757883101327 4233.987087488412 0.6483532387057357 0.9116935015488603 0.9386794885494216 1.1541969722054861 0.6545660687654179 0.6864111336728275 0.8236211233416187 1.12563573944969 1.0202576894639974 1.0 12.047801154185946 -7.752205874015725 24.99280506634593 1.0547100397818887 0.8383888857939904 0.31250394730027364 0.1475116461856525 248.3852276739321 672321.731189228 0.07569597695237502 0.0429231558855081 1.7692700504030742e-08 7.752205874015725 -0.2163211539878983 MT(ph)EVKCQHY(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MTEVKCQHYK 10 1 B7Z2D2 B7Z2D2 CEP70 2 MT(1)EVKCQHY(1)K 69.01 0.024073 0.0 19929.0 25297.0 20085.0 14607.0 18125.0 13108.0 15774.0 14450.0 12917.0 13127.0 True False 23302.586084308034 27808.318977951265 20563.902572786672 13788.617146532953 14573.53636140117 12420.593404684809 14279.772526129673 14070.702811040557 13105.886688436847 15506.821186725168 1.5027313337601738 1.793295907852279 1.3261197975501704 0.8891968882917727 0.939814561986247 0.8009761159377804 0.9208703933694723 0.9073879579578811 0.8451691375442134 1.0 13.920615351663377 -5.588848288294021 3.0506697909881364 0.8930962573609365 1.644026113644961 0.9260393600229604 0.08587411674122125 0.05322548524405487 0.996724005158219 0.022535787277025165 0.045040559057729426 2.5772212981997834e-06 5.588848288294021 0.7509298562840245 MT(ph)LEAIRY(ph)S(ph)RGSLQILDQLLLPKQS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 MTLEAIRYSRGSLQILDQLLLPKQSR 26 3 Q9BV20-2;Q9BV20 Q9BV20-2 MRI1 Methylthioribose-1-phosphate isomerase 4 MT(0.927)LEAIRY(0.98)S(0.982)RGS(0.11)LQILDQLLLPKQS(1)R 49.125 0.018657 5277600.0 2741.3 2948.9 3463.9 6184.2 6847.4 5433.5 4695.8 6799.8 4855.5 5168.6 True False 3612.9763774178386 3902.074256117487 3417.966422727946 4758.528234937556 5896.75670472755 5093.74238605614 5113.717103030022 5749.047153859327 5112.151817300284 4987.648887199399 0.7243846668297759 0.7823474234788268 0.6852860937144192 0.9540623934355379 1.1822718154562444 1.021271244479343 1.0252760807109282 1.152656749478502 1.0249622483291512 1.0 12.284144192787686 -5.9193375960588375 4.24089394962238 1.0712061798524124 0.7377347968891304 0.859819198292896 0.06068507396601542 0.070309963209065 2.400045967581359 0.016859866495206436 0.025601039499483603 1.2040995773175648e-06 5.9193375960588375 -0.33347138296328205 MT(ph)MLQES(ph)FSFDDLSVDFTQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MTMLQESFSFDDLSVDFTQK 20 0 F5H0T0;J3KQ53;F5H1R3;F5H6X5;F5H3F5;F5H1B1;F5H630;P51523 F5H0T0 ZNF84 Zinc finger protein 84 2 MT(0.997)MLQES(0.981)FS(0.015)FDDLS(0.003)VDFT(0.003)QK 49.537 0.041436 0.0 729.28 0.0 98290.0 3404.2 24232.0 15993.0 2755.9 3138.4 14704.0 1286.7 True False 852.7327000634335 0.0 100633.60636690083 3213.473710565307 19483.913550867484 15154.29892593256 2494.841201011839 3056.020325409666 14919.018182764992 1519.9685244884047 0.5610199726671634 0.0 66.207690978846 2.1141712205171532 12.818629620916285 9.970139961308236 1.6413768843348646 2.010581322029856 9.815346793307103 1.0 10.569825733308148 MT(ph)NNEDSLSPTSSTLSNLELDAAEKDR ddPTM_PC-9_AZD4547_30min_R2 1 MTNNEDSLSPTSSTLSNLELDAAEKDR 27 1 Q9ULH7-4;Q9ULH7;Q9ULH7-5 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2 1 MT(0.887)NNEDS(0.094)LS(0.016)PT(0.003)S(0.001)STLSNLELDAAEKDR 115.01 5.0355e-12 17256000.0 11479.0 10055.0 12164.0 16739.0 16971.0 14445.0 13343.0 16312.0 11515.0 11297.0 True False 15129.083221967454 13305.082113758115 12002.697412183594 12880.082164971993 14614.869590783546 13541.751866491393 14530.501151183953 13791.35521246998 12123.659391661586 10901.49546853919 1.3877988818716416 1.22048228632076 1.1010138422588334 1.1814968140970052 1.3406297909273865 1.2421921291048337 1.332890628915801 1.265088377302975 1.1121097492219723 1.0 13.412238437217258 -8.470729316074822 3.0299073915811867 1.001749092798893 1.2543306759467578 0.5357808599494409 0.07876198491853832 0.19355843710925083 3.858180624934394 0.08061004238012946 0.021552469304770214 3.3827560849072075e-09 8.470729316074822 0.25258158314786483 MT(ph)T(ph)S(ph)S(ph)IR ddPTM_PC-9_Lapatinib_30min_R1 1 MTTSSIR 7 0 F6PQP6;E9PBC1;I3L2B2;O95208-2;O95208;J3KSR0;J3QKL8;J3KSF8;J3KTF6;J3KSA6;J3KSC7;J3QLN2 F6PQP6 EPN2 Epsin-2 4 MT(1)T(1)S(1)S(1)IR 63.534 0.023639 28456000.0 63738.0 48952.0 59186.0 51570.0 55573.0 49800.0 49552.0 48243.0 62963.0 50662.0 True False 62829.08443188233 48838.65465160189 54319.955544566896 55362.6298324769 52304.30540072178 47670.17008947 52117.560100201874 50484.5458997302 55871.44391021656 59418.85919712831 1.0573929772606412 0.8219386119409415 0.9141871163220205 0.931734984153862 0.8802643825119016 0.802273398271064 0.877121520076587 0.8496384242626135 0.940298158954166 1.0 15.858633286196271 -4.748188972639653 24.91194282648414 0.8846121785784944 1.0573934143214667 0.4385905135658309 0.05613942689648275 565.5381367239542 1063196.750854627 0.013482320311150788 0.2518994660974524 1.7857103975015696e-05 4.748188972639653 0.17278123574297233 MT(ph)VVGNPR ddPTM_PC-9_Lapatinib_30min_R1 1 MTVVGNPR 8 0 E9PP24;E9PJC4;E9PQY7;E9PS99;E9PL78;E9PJM1;E9PMQ9;E9PSI1;O15321-2;O15321 E9PP24 TM9SF1 Transmembrane 9 superfamily member 1 1 MT(1)VVGNPR 84.213 0.031010000000000003 0.0 14570.0 24627.0 21783.0 19493.0 24056.0 20249.0 20028.0 24069.0 29911.0 22078.0 True False 14362.22912818923 24569.97769457837 19992.085824811627 20926.580246741756 22641.073375915705 19382.997472724463 21064.951842243372 25187.33360820443 26542.10820320646 25894.15288291419 0.5546514378412394 0.9488620000691526 0.7720695060081715 0.8081585190821129 0.8743701127544908 0.7485472708981339 0.8135022581156813 0.9727035181299117 1.02502322911362 1.0 14.660338741586108 -7.790350462018211 3.6658480290972504 1.0085716852539994 0.7950243339408132 0.5085991442946411 0.09539891860685894 0.18653921140606156 5.246180209906488 0.052264829204771136 0.024550045777893513 1.620501875422735e-08 7.790350462018211 -0.21354735131318625 MTDQEAIQDLWQWR ddPTM_PC-9_AZD4547_30min_R2 5 MTDQEAIQDLWQWR 14 0 P06748;P06748-2 P06748 NPM1 Nucleophosmin 0 ;;;; 158.34 0.0008705 42977100.0 53500.6 53571.5 85742.3 108413.0 90993.0 85622.0 60850.5 87038.0 67586.6 83795.2 False True 70512.67791838937 70887.43972721961 84605.30107897632 83420.05781415298 78360.19260350983 80268.04280461934 66266.07661696163 73588.27703426698 71159.0896952214 80861.55555327398 0.8720173317953738 0.8766519422263261 1.0462982130393947 1.0316405273602904 0.9690661040014722 0.9926601368896049 0.8195003937724593 0.9100527009498952 0.8800113874675548 1.0 16.303166336898954 -7.231782430902554 24.980253243179128 0.8948954783500399 0.9676663457485569 0.1658149495733191 0.0674665355557287 1161.8805423766269 978661.3878259849 0.027061096533009626 0.020958227990374445 5.864318765122393e-08 7.231782430902554 0.07277086739851701 MTDQEAIQDLWQWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 MTDQEAIQDLWQWR 14 0 P06748;P06748-2 P06748 NPM1 Nucleophosmin 0 ;;;;; 192.14 3.9591e-06 40927900.0 48039.00000000001 52003.2 57440.3 60704.0 68147.9 62098.200000000004 60249.200000000004 57809.5 60666.8 45752.4 False True 56171.05388650077 57165.73401882417 58809.89459555081 57302.95168502339 54794.8081987934 58841.66107436661 54541.95960956587 56292.061879228284 61553.93717969038 54046.94794420087 1.0393011265778203 1.0577051284716983 1.0881260983740895 1.0602439890626958 1.0138372337946748 1.088713855500516 1.009158919868631 1.0415400687814105 1.1388975607510692 1.0 15.721925530162686 -10.905607399361372 5.311943326971725 0.9999694862942018 1.0579969775706342 0.19246701840408087 0.03654713757236254 1.2859145278035917e-05 1.4942642133483863e-06 0.03445462962115562 0.00835208201370568 1.2427752642791296e-11 10.905607399361372 0.058027491276432364 MTDQEAIQDLWQWR ddPTM_PC-9_Lapatinib_30min_R1 5 MTDQEAIQDLWQWR 14 0 P06748;P06748-2 P06748 NPM1 Nucleophosmin 0 ;;;; 206.18 3.9938999999999995e-10 13259900.0 51081.3 46996.4 54884.8 47176.00000000001 55898.8 50907.899999999994 43923.8 38781.5 55666.4 43242.0 False True 50352.87129483683 46887.58272325021 50372.38360545476 50645.48041452259 52610.94248526923 48730.68778911105 46197.95944319602 40583.430068826325 49396.66383882091 50716.322083656836 0.9928336524833071 0.924506762259079 0.9932183868216085 0.9986031781047255 1.0373572121118564 0.9608482198044552 0.9109091027340714 0.8002045180224967 0.9739796146365042 1.0 15.63016250546718 -7.168058699847415 3.8826061776124634 0.9045090135237989 0.9871464335721134 0.22162030300681845 0.05625086863257466 0.2909058719482258 8.02204336108991 0.02236058476057036 0.016821769392035325 6.791118367114201e-08 7.168058699847415 0.08263742004831454 MTGSAPPPS(ph)PTPNK ddPTM_PC-9_AZD4547_30min_R2 1 MTGSAPPPSPTPNK 14 0 Q9UBW7 Q9UBW7 ZMYM2 Zinc finger MYM-type protein 2 1 MTGS(0.003)APPPS(0.965)PT(0.032)PNK 106.6 0.0007575 14660000.0 43981.0 44080.0 53479.0 61212.0 54802.0 60385.0 59343.0 64769.0 55225.0 54816.0 True False 57966.04313837013 58327.99796861839 52769.833517442166 47100.51911597259 47193.68825137706 56609.11640415941 64624.41203737607 54760.43929355496 58144.08075592796 52896.908524691884 1.0958304512505113 1.1026730974531584 0.9975976855586863 0.8904210175909697 0.892182351816409 1.0701781632046548 1.2217048942890467 1.0352294835527713 1.0991961983711531 1.0 15.690895788345765 -6.983605003265913 24.969398005618316 1.0996788886075262 0.9944582854504231 0.21556698884555858 0.08500642491700115 362.8370670305314 552594.4836390852 0.032538963280322054 0.028689463248851802 1.0384724912736142e-07 6.983605003265913 -0.10522060315710302 MTGSAPPPS(ph)PTPNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 MTGSAPPPSPTPNK 14 0 Q9UBW7 Q9UBW7 ZMYM2 Zinc finger MYM-type protein 2 1 MTGSAPPPS(0.992)PT(0.008)PNK;MTGSAPPPS(0.5)PT(0.5)PNK;MTGSAPPPS(0.933)PT(0.067)PNK 119.77 8.4801e-05 7192600.0 116136.0 151135.0 138536.0 137022.0 170835.0 109916.0 146278.0 123533.0 120923.0 111233.0 True False 135795.5310094432 166138.68398358178 141839.2236407059 129345.10157131772 137361.10809930865 104151.81146394074 132421.48887899067 120290.38964403298 122691.27011115979 131398.66238005634 1.0334620501437783 1.264386417443457 1.079457135038798 0.9843715242488624 1.0453767611576332 0.792639815180865 1.0077841469647226 0.9154612951546349 0.9337330220020705 1.0 17.003591063738746 -5.8128626857937205 1.737179100833086 0.9390947615813167 1.1538178103385102 0.4829382151097319 0.08321116573849864 0.27718950798068265 1.7063757985641759 0.025405009117689496 0.05058049188182399 1.5386410473054415e-06 5.8128626857937205 0.2147230487571935 MTGSAPPPS(ph)PTPNK ddPTM_PC-9_Lapatinib_30min_R1 3 MTGSAPPPSPTPNK 14 0 Q9UBW7 Q9UBW7 ZMYM2 Zinc finger MYM-type protein 2 1 MTGSAPPPS(0.99)PT(0.01)PNK;MT(0.001)GS(0.001)APPPS(0.925)PT(0.072)PNK;MTGSAPPPS(0.803)PT(0.197)PNK 162.64 5.019e-13 9832900.0 72893.0 102551.0 106423.0 102593.0 117969.0 119078.0 109540.0 118804.0 121229.0 101746.0 True False 71853.53245306094 102313.5494602147 97673.31174466001 110138.03146021538 111030.29535597753 113985.31152437585 115211.44521666376 124324.06755532503 107574.91342203582 119332.66053197697 0.6021279684266044 0.8573809467090382 0.8184960538819712 0.9229496013013323 0.9304267152094988 0.9551895601441969 0.9654644814173998 1.0418276689809538 0.9014708374260164 1.0 16.86462942726734 -4.034792624777271 0.6077087323947085 0.9756097099384036 7.50281942544581e-17 0.8354917521781041 0.04731519633202562 3.0032669664479017 0.4303958809035986 0.021077760824879933 2.5103077620343734 9.230120593700671e-05 4.034792624777271 -0.9756097099384035 MTNGFSGADLTEICQR ddPTM_PC-9_Lapatinib_30min_R1 1 MTNGFSGADLTEICQR 16 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 97.631 0.028858999999999996 3461300.0 9814.2 12411.0 11053.0 13002.0 11665.0 9817.6 11084.0 9195.5 12628.0 10568.0 False True 9674.247708296143 12382.26309202957 10144.265005813842 13958.21045340052 10978.88763427239 9397.724133943393 11657.875285571472 9622.756499823166 11205.701661264795 12394.664719025153 0.7805170956699365 0.9989994382843977 0.8184380324739994 1.1261466743812285 0.8857752817968831 0.7582072082610177 0.9405559206193977 0.7763627914075598 0.9040746091392563 1.0 13.597431625984822 -6.510030573553295 24.986876484229334 0.8610279277823096 0.9376039403917249 0.044062132315448754 0.11109716515444533 1497.0790380357153 2911495.8827160657 0.03342573041759611 0.03617866675471846 3.0900778889102044e-07 6.510030573553295 0.07657601260941527 MTNNEDS(ph)LSPTSSTLSNLELDAAEKDR ddPTM_PC-9_AZD4547_30min_R2 1 MTNNEDSLSPTSSTLSNLELDAAEKDR 27 1 Q9ULH7-4;Q9ULH7;Q9ULH7-5 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2 1 MT(0.203)NNEDS(0.428)LS(0.301)PT(0.063)S(0.005)S(0.001)TLSNLELDAAEKDR 86.946 1.0761e-06 15750000.0 30992.0 30515.0 39187.0 52131.0 52310.0 43848.0 40343.0 46808.0 40524.0 43387.0 True False 40846.81132635378 40378.37699665135 38667.35477566906 40113.00336592117 45047.65943632594 41106.1776283776 43933.448845253246 39574.89914083464 42666.01590861432 41868.03433597502 0.9756085274645017 0.9644201748911894 0.9235531447542599 0.9580818398119578 1.0759439785215528 0.9818033800802825 1.0493315375807726 0.9452294517402264 1.01905944679026 1.0 15.353561566070221 -6.040675555836117 24.995790011281603 1.010204265076584 0.9530666908068354 0.37804842889629864 0.03545647569128264 525.0225481364813 322633.89554280054 0.01016582724513849 0.013125790099786108 9.105932866844938e-07 6.040675555836117 -0.057137574269748526 MTNNEDS(ph)LSPTSSTLSNLELDAAEKDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 MTNNEDSLSPTSSTLSNLELDAAEKDR 27 1 Q9ULH7-4;Q9ULH7;Q9ULH7-5 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2 1 MT(0.001)NNEDS(0.48)LS(0.48)PT(0.029)S(0.008)S(0.002)T(0.001)LSNLELDAAEKDR;MT(0.01)NNEDS(0.464)LS(0.464)PT(0.05)S(0.005)S(0.006)T(0.002)LSNLELDAAEKDR;MT(0.172)NNEDS(0.35)LS(0.35)PT(0.041)S(0.041)S(0.019)T(0.022)LS(0.005)NLELDAAEKDR 78.531 0.00015452 24767600.0 24735.6 22192.5 23319.0 30150.8 31728.7 33920.7 31050.1 26892.3 28044.7 21299.9 True False 28922.848529630668 24395.624734876994 23875.013397799958 28461.548426212477 25511.689001378716 32141.83877802043 28108.809744743186 26186.40561974713 28454.800682140172 25161.40326008438 1.1494926666317289 0.9695653490669098 0.948874478542096 1.1311590268641094 1.0139215503075707 1.277426320216794 1.1171399883461397 1.040737090418514 1.130890848495735 1.0 14.618924763607307 -5.780413521199463 24.99998566625193 1.107627069533629 1.0173362560365045 0.13859262338031342 0.08904505992998393 407.4485088166831 536845.5948254581 0.025016132440263825 0.03717372443762186 1.6580074543782339e-06 5.780413521199463 -0.09029081349712453 MTNNEDS(ph)LSPTSSTLSNLELDAAEKDR ddPTM_PC-9_Lapatinib_30min_R1 1 MTNNEDSLSPTSSTLSNLELDAAEKDR 27 1 Q9ULH7-4;Q9ULH7;Q9ULH7-5 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2 1 MT(0.015)NNEDS(0.626)LS(0.224)PT(0.06)S(0.06)S(0.01)T(0.005)LSNLELDAAEKDR 80.813 3.033e-05 30595000.0 54913.0 42163.0 51181.0 48175.0 50488.0 50295.0 46546.0 47629.0 48268.0 41878.0 True False 54129.93055018914 42065.37416398702 46973.09574437331 51717.95020708888 47518.39510322712 48144.00009337139 48955.92412867287 49842.017218213 42831.549555426725 49116.55650107261 1.1020709594942195 0.856439806871811 0.9563597102607857 1.0529636825407225 0.9674618598758936 0.9801990107413172 0.9967295677090833 1.0147701868538879 0.8720389336433095 1.0 15.583921798299704 -10.449824313181049 4.77773592056002 1.0000001193637207 0.9771183817317657 0.008964493162639697 0.07021864664257986 1.2124447554081516e-07 2.7262940144075535e-08 0.0645107637872545 0.015646041610649038 3.549569522961803e-11 10.449824313181049 -0.022881737631955 MTNNEDS(ph)LSPTSSTLSNLELDAAEKDRK ddPTM_PC-9_AZD4547_30min_R2 1 MTNNEDSLSPTSSTLSNLELDAAEKDRK 28 2 Q9ULH7-4;Q9ULH7;Q9ULH7-5 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2 1 MT(0.121)NNEDS(0.544)LS(0.322)PT(0.011)S(0.002)STLSNLELDAAEKDRK 69.133 0.00048182 7655400.0 11453.0 8323.1 18590.0 33165.0 24969.0 17089.0 15822.0 15605.0 12539.0 18272.0 True False 15094.815762801045 11013.379307908528 18343.484453509773 25519.32164414218 21502.485346312787 16020.42212852 17230.127348724614 13193.60581722622 13201.785941124144 17632.302841563964 0.8560887309182669 0.6246137788620045 1.0403340175322628 1.4473050896101014 1.2194938766379277 0.9085836531094318 0.97719098313742 0.7482633400627302 0.7487272683409266 1.0 14.105933287624609 -7.4906037646716355 2.346126738926963 0.8153853556451071 1.0299363048563142 0.11849283171301173 0.21583349670612204 0.6795673864367543 7.407149057564247 0.13454139445732272 0.07381717062302613 3.231441032686893e-08 7.4906037646716355 0.2145509492112071 MTNNEDSLS(ph)PTSSTLSNLELDAAEKDR ddPTM_PC-9_AZD4547_30min_R2 2 MTNNEDSLSPTSSTLSNLELDAAEKDR 27 1 Q9ULH7-4;Q9ULH7;Q9ULH7-5 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2 1 MT(0.001)NNEDS(0.204)LS(0.498)PT(0.145)S(0.104)S(0.032)T(0.014)LS(0.001)NLELDAAEKDR;MT(0.001)NNEDS(0.123)LS(0.747)PT(0.123)S(0.006)STLSNLELDAAEKDR 127.3 1.8108000000000004e-10 96465000.0 60575.0 57596.0 85220.0 121638.0 109421.0 90446.0 88887.0 93607.0 74376.0 84763.0 True False 79836.58996172824 76212.78064883266 84089.92711824119 93596.23838836624 94229.78289394436 84790.39732202701 96797.77080306433 79142.1890248698 78307.36351838651 81795.47316984908 0.9760514471986341 0.9317481480983195 1.028051111626039 1.1442716175015304 1.1520170889931196 1.0366147909672085 1.183412321633776 0.9675619683809432 0.957355712776189 1.0 16.319733381443548 -5.451151642156141 4.934595144799773 1.070496432901601 0.9566019953747762 0.24605065840012819 0.07447912605812339 0.29183597666615313 13.212763811994794 0.020795103554777924 0.04398870612361186 3.5387375777408704e-06 5.451151642156141 -0.11389443752682471 MTNNEDSLS(ph)PTSSTLSNLELDAAEKDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 MTNNEDSLSPTSSTLSNLELDAAEKDR 27 1 Q9ULH7-4;Q9ULH7;Q9ULH7-5 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2 1 MT(0.015)NNEDS(0.296)LS(0.564)PT(0.115)S(0.008)S(0.002)TLSNLELDAAEKDR;MT(0.017)NNEDS(0.186)LS(0.693)PT(0.069)S(0.02)S(0.014)T(0.001)LSNLELDAAEKDR;MT(0.011)NNEDS(0.214)LS(0.583)PT(0.143)S(0.038)S(0.009)T(0.001)LSNLELDAAEKDR 90.836 4.7303999999999995e-07 113810000.0 104361.0 95291.0 103499.0 127149.0 139432.0 131091.0 130291.0 137134.0 116466.0 106953.0 True False 122027.25607629462 104750.86072372044 105966.80868214351 120025.25375262012 112111.30052098674 124216.3571874837 117948.89325484738 133534.3778054836 118169.09491797494 126342.73226051782 0.9658430991081884 0.8291008026304585 0.8387250044873235 0.949997293909466 0.8873585248244753 0.983169787173436 0.9335629453670322 1.0569217193287908 0.9353058367798404 1.0 16.94698315151509 -6.742185291165453 1.1041451417629613 0.9922025118825091 0.8806429172285829 0.40041629808332 0.05208868930519417 0.4586333030895388 1.1903344094432151 0.026728086896537686 0.02461506238414841 1.8105674516031775e-07 6.742185291165453 -0.11155959465392618 MTNNEDSLS(ph)PTSSTLSNLELDAAEKDR ddPTM_PC-9_Lapatinib_30min_R1 4 MTNNEDSLSPTSSTLSNLELDAAEKDR 27 1 Q9ULH7-4;Q9ULH7;Q9ULH7-5 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2 1 MT(0.261)NNEDS(0.301)LS(0.37)PT(0.054)S(0.009)S(0.004)TLSNLELDAAEKDR;MT(0.054)NNEDS(0.178)LS(0.597)PT(0.129)S(0.029)S(0.009)T(0.003)LSNLELDAAEKDR;MT(0.193)NNEDS(0.109)LS(0.471)PT(0.109)S(0.109)S(0.009)T(0.002)LSNLELDAAEKDR;MT(0.022)NNEDS(0.197)LS(0.607)PT(0.137)S(0.033)S(0.003)T(0.001)LSNLELDAAEKDR 84.12700000000001 4.6873999999999995e-07 58833300.0 90185.0 72823.0 75492.0 63712.0 84579.0 75055.0 72579.0 73248.0 78135.0 61983.0 True False 88898.9453620964 72654.38281773182 69285.33916754702 68397.5930170015 79604.22950871187 71845.07261175038 76336.78548822556 76651.36948497067 69334.6135019737 72696.67896284403 1.222874918502584 0.9994181832551962 0.9530743378656874 0.9408626912924065 1.0950187910151763 0.9882854847945817 1.0500725284471664 1.0543998787640343 0.9537521450933306 1.0 16.149601837872115 -4.760411700751417 24.951679240346632 1.0058239195203962 1.2228751813422485 0.6584770726623821 0.04729671093395831 15.825442470665168 384045.0117516517 0.012046453250033643 0.07146308848451832 1.7361542158464497e-05 4.760411700751417 0.2170512618218523 MTNNEDSLSPT(ph)SSTLSNLELDAAEKDR ddPTM_PC-9_AZD4547_30min_R2 1 MTNNEDSLSPTSSTLSNLELDAAEKDR 27 1 Q9ULH7-4;Q9ULH7;Q9ULH7-5 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2 1 MTNNEDS(0.074)LS(0.203)PT(0.565)S(0.126)S(0.029)T(0.004)LSNLELDAAEKDR 107.95 3.1617e-10 4839000.0 11445.0 13013.0 14729.0 19726.0 19547.0 16584.0 17078.0 17780.0 15753.0 17514.0 True False 15084.271929211382 17219.197766915404 14533.683836242362 15178.475463661962 16833.236455780218 15546.999858351903 18597.9089155302 15032.50954375407 16585.671419613103 16900.840190846717 0.8925160973583334 1.0188367899153976 0.8599385398670075 0.8980899938857735 0.9959999778529879 0.9198950870366767 1.1004132756431004 0.8894533865775198 0.9813518873810602 1.0 14.04480734848519 -6.264422245311893 24.930382854242552 0.978555130146023 0.9204942564019074 0.1889966752085035 0.06451707871141209 491.0371737531759 4104022.6934950063 0.01929419823914443 0.022843733777467286 5.439735142721441e-07 6.264422245311893 -0.058060873744115615 MTNNEDSLSPT(ph)SSTLSNLELDAAEKDR ddPTM_PC-9_Lapatinib_30min_R1 1 MTNNEDSLSPTSSTLSNLELDAAEKDR 27 1 Q9ULH7-4;Q9ULH7;Q9ULH7-5 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2 1 MTNNEDS(0.009)LS(0.223)PT(0.757)S(0.009)S(0.003)T(0.001)LSNLELDAAEKDR 119.52 3.0673e-12 7343100.0 35055.0 34898.0 33774.0 32086.0 35798.0 35136.0 34348.0 31334.0 32979.0 29774.0 True False 34555.10927170034 34817.19582512675 30997.23209141018 34445.711475758275 33692.43202157591 33633.31518601644 36126.37137394525 32789.89203039086 29264.557735734194 34920.396228638776 0.9895394383687188 0.9970446955173037 0.887654077246376 0.9864066618897295 0.9648353300740673 0.9631424273025064 1.034534978853345 0.9389896900281831 0.8380362451825177 1.0 15.091782308329206 -7.997934175956151 24.973159558191824 0.9088497311112916 0.9729314554939585 0.16593303845440577 0.05058692873233495 88.66484944690069 1071848.8670339228 0.026800864969978726 0.012733556909466846 1.0047680668745542e-08 7.997934175956151 0.0640817243826669 MTNNEDSLSPTSST(ph)LSNLELDAAEK ddPTM_PC-9_Lapatinib_30min_R1 1 MTNNEDSLSPTSSTLSNLELDAAEK 25 0 Q9ULH7-4;Q9ULH7;Q9ULH7-5 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2 1 MT(0.126)NNEDS(0.089)LS(0.075)PT(0.025)S(0.025)S(0.025)T(0.431)LS(0.205)NLELDAAEK 58.812 0.030897000000000004 0.0 5581.1 9551.5 8007.8 5907.9 11364.0 8799.7 9640.3 8887.1 8601.1 8679.9 True False 5501.512490551613 9529.384088592413 7349.429595001912 6342.386674176656 10695.591862483616 8423.357344102602 10139.427563649826 9300.027109953622 7632.353544401693 10180.209149760258 0.540412520962909 0.9360695785721483 0.7219330651153656 0.6230114313836095 1.0506259454144413 0.8274247827512434 0.9959940325871014 0.9135398863757761 0.7497246306163989 1.0 13.313479581063483 -6.255452464356234 24.998300350763618 0.9174443271754192 0.7230201757237517 0.4186645745559283 0.12478383689102451 538.3389445288309 2247827.850940024 0.03617657065969326 0.04545179462627986 5.553253968593729e-07 6.255452464356234 -0.19442415145166758 MTPPTT(ph)KPVMTDS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 MTPPTTKPVMTDSK 14 1 J3QRZ9;J3QLI3 J3QRZ9 2 MT(0.003)PPT(0.431)T(0.566)KPVMT(0.232)DS(0.768)K 80.102 0.012573 4237800.0 6874.0 7355.2 14313.0 18336.0 12244.0 12625.0 9897.6 14820.0 12084.0 13753.0 True False 9059.789011917792 9732.624561224633 14123.200268051944 14108.918488376039 10544.131946824215 11835.556754202415 10778.467225808157 12529.909529720762 12722.73557002505 13271.5116560874 0.6826493655500225 0.7333470981627369 1.06417419763738 1.0630980745817706 0.7944936658355579 0.8918017073641842 0.8121506807300487 0.9441207493476089 0.9586500693905027 1.0 13.696045085942082 -5.1172344126946605 6.348335065798227 0.9314216010297605 0.6952782100113196 0.5359125283897023 0.08685825002983434 0.18368639864304875 8.700866822577414 0.023826488969402232 0.06523918714504226 7.63423610505917e-06 5.1172344126946605 -0.23614339101844084 MTSERAPSPS(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 1 MTSERAPSPSSR 12 1 Q9UQ35;I3L3Q8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 MT(0.001)S(0.001)ERAPS(0.333)PS(0.637)S(0.029)R 90.689 0.032876999999999997 2772900.0 67667.0 4914.7 5706.2 6308.7 3853.3 5435.9 3458.0 3605.4 7140.8 2676.3 True False 66702.05617139213 4903.32031410827 5237.058262568979 6772.66284320626 3626.656469879278 5203.419228701807 3637.0383198760524 3772.920046159803 6336.527908042416 3138.894889054409 21.25017196465795 1.5621167600121182 1.6684401509687512 2.157658374233271 1.1553927729551363 1.6577233111075393 1.1587002586670587 1.2019899294227065 2.018712996774254 1.0 11.616041003426357 -4.761438435772206 11.20971411480291 1.5205769587023863 21.29194874116335 0.9962181490376353 0.3648968658126034 0.0033366647006188525 15.572101539104693 0.08898805428735834 0.4995491381894381 1.732054543984442e-05 4.761438435772206 19.771371782460964 MTTTSAAAY(ph)GTHLSPHVPHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MTTTSAAAYGTHLSPHVPHR 20 0 P16144-4;P16144-2;P16144-3;P16144;J3QRK0 P16144-4 ITGB4 Integrin beta-4 1 MT(0.069)T(0.069)T(0.069)S(0.069)AAAY(0.292)GT(0.174)HLS(0.257)PHVPHR 51.089 0.03951 0.0 7720.5 6373.2 9444.9 8920.5 12969.0 9216.9 8502.7 9262.7 8689.9 7378.4 True False 9027.42816317428 7005.889176988541 9670.102235982718 8420.713305651205 10427.817548745481 8733.549538574869 7697.262701782855 9019.563939641892 8816.973347824365 8716.045512617733 1.0357252208132433 0.8037921746560991 1.1094598143141692 0.9661162614927845 1.1963931961632956 1.002008253161574 0.8831141015314752 1.0348229511404883 1.0115795443083133 1.0 13.089458014463368 -5.272114548639666 24.977782672836486 1.0247477509887033 0.9197586876199704 0.1680570635385391 0.09404092967437232 1107.0633135742096 2590311.0302128107 0.024357388419661407 0.05154197496914443 5.344233823686743e-06 5.272114548639666 -0.10498906336873293 MTTTSAAAYGT(ph)HLSPHVPHR ddPTM_PC-9_AZD4547_30min_R2 1 MTTTSAAAYGTHLSPHVPHR 20 0 P16144-4;P16144-2;P16144-3;P16144;J3QRK0 P16144-4 ITGB4 Integrin beta-4 1 MTTTSAAAY(0.175)GT(0.798)HLS(0.027)PHVPHR 72.48899999999999 0.0023355 34031000.0 5408.8 7003.6 11796.0 17729.0 12440.0 12919.0 14200.0 18996.0 15568.0 11532.0 True False 7128.685889971036 9267.376737137383 11639.577332630519 13641.852960319513 10712.92073003048 12111.172887726018 15463.772490954965 16060.604684654221 16390.892697298095 11128.268190067613 0.6405925673442746 0.8327779829577487 1.04594687455675 1.2258738491309338 0.962676361411936 1.0883250368225026 1.3895938008356905 1.4432258829805071 1.4729059739886183 1.0 13.441941473756671 -4.505780283713943 0.4663821558266314 1.3239042921907163 3.517098211290902e-13 0.6115284403089938 0.16132005043201572 4.29782428624086 0.5981413871012875 0.11502672528349107 3.3117957248958234 3.120467877713562e-05 4.505780283713943 -1.3239042921903645 MTTTSAAAYGTHLS(ph)PHVPHR ddPTM_PC-9_AZD4547_30min_R2 2 MTTTSAAAYGTHLSPHVPHR 20 0 P16144-4;P16144-2;P16144-3;P16144;J3QRK0 P16144-4 ITGB4 Integrin beta-4 1 MTTTSAAAY(0.001)GT(0.003)HLS(0.996)PHVPHR;MTTTSAAAY(0.001)GT(0.002)HLS(0.996)PHVPHR 100.9 0.00011505 39566800.0 14503.9 32909.0 54267.0 76737.0 58143.0 32692.0 56418.0 72164.0 53068.0 51090.0 True False 19115.83850013884 43546.19067942975 53547.38412257212 59046.4702248316 50070.84807123488 30647.764071951304 61439.092703851886 61012.711963749614 55873.06613953079 49301.354650585716 0.3877345487891526 0.8832656016869185 1.0861239919689702 1.1976642557453563 1.0156079569436338 0.6216414191691424 1.2461948183633118 1.2375463594492684 1.1332967731925598 1.0 15.589339667548826 -4.772729774667554 2.425430020609811 1.0682413403140412 0.22115435711190926 0.5922012516786621 0.1701035144239064 0.42720391761871007 3.0556471757795256 0.047695205503724865 0.777085324397319 1.6876027535981446e-05 4.772729774667554 -0.8470869832021319 MTTTSAAAYGTHLS(ph)PHVPHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 MTTTSAAAYGTHLSPHVPHR 20 0 P16144-4;P16144-2;P16144-3;P16144;J3QRK0 P16144-4 ITGB4 Integrin beta-4 1 MTTTSAAAY(0.022)GT(0.341)HLS(0.636)PHVPHR;MTTTSAAAY(0.013)GT(0.037)HLS(0.95)PHVPHR;MTTTSAAAY(0.022)GT(0.076)HLS(0.902)PHVPHR 70.335 0.0016577999999999999 52016000.0 22911.9 35210.0 68780.0 66939.0 132259.0 66376.0 60682.0 61318.0 56367.0 39852.2 True False 26790.432139347555 38705.4161052166 70419.9760496027 63188.624849166124 106343.79837917558 62895.125711730194 54933.761660365184 59708.46747179137 57191.26073911277 47077.0883901584 0.5690758085401936 0.8221709844168714 1.4958439117132019 1.342237317768698 2.258928961320536 1.3360028808595266 1.1668895324429036 1.2683126657483261 1.2148427758558824 1.0 15.522737475308677 -5.134897521033653 3.479000684637408 1.4157038182226498 0.6092234232011051 0.42887706769687206 0.3216848595080484 0.2294198213864578 4.95942498085921 0.08807668529121102 0.29356501753061776 7.329974756121194e-06 5.134897521033653 -0.8064803950215447 MTTTSAAAYGTHLS(ph)PHVPHR ddPTM_PC-9_Lapatinib_30min_R1 3 MTTTSAAAYGTHLSPHVPHR 20 0 P16144-4;P16144-2;P16144-3;P16144;J3QRK0 P16144-4 ITGB4 Integrin beta-4 1 MTTTSAAAY(0.268)GT(0.059)HLS(0.673)PHVPHR;MTTTSAAAY(0.021)GT(0.008)HLS(0.971)PHVPHR;MTTTSAAAY(0.001)GT(0.004)HLS(0.995)PHVPHR 95.209 0.00069674 27959400.0 68648.0 54599.0 35489.9 31613.6 38959.8 24230.4 19592.2 21860.5 56323.0 15006.0 True False 67669.06693149847 54472.57937005255 32572.057416975742 33938.56960387805 36668.261161913884 23194.122275821188 20606.588250629142 22876.2186356788 49979.3106325164 17599.767105761865 3.844884226300061 3.0950738747116233 1.8507095702597225 1.9283533355828977 2.083451499191107 1.3178652954008594 1.1708443712236904 1.2998023495543596 2.83977113629839 1.0 14.10326871764012 -4.822571086555051 1.0200903254644946 1.5982328775677872 5.0280655068631654 0.6769806443816444 0.5072935375401979 1.0389515375812417 0.9104508825499495 0.16746771750245829 3.8592103186442297 1.5046272169863869e-05 4.822571086555051 3.4298326292953782 MTVQAT(ph)PSSTTEETAT(ph)QK ddPTM_PC-9_Lapatinib_30min_R1 1 MTVQATPSSTTEETATQK 18 0 H0YDV8 H0YDV8 CD44 2 MT(0.02)VQAT(0.779)PS(0.09)S(0.107)T(0.002)T(0.002)EET(0.289)AT(0.711)QK 83.064 0.0026715999999999997 16298000.0 18101.0 24700.0 87668.0 32486.0 80950.0 105470.0 69578.0 70614.0 107070.0 27493.0 True False 17842.87642068314 24642.808667563488 80460.27544826626 34875.12881011914 76188.68015382337 100959.29396257848 73180.40839223133 73894.98422908093 95010.64910291594 32245.128417880238 0.5533510733605604 0.7642335408997413 2.4952691893653696 1.081562720363692 2.3627966112107655 3.1309937009460183 2.2695027739958413 2.291663511816112 2.946511729512344 1.0 14.976793594713303 -5.101377121655093 0.9326463003747678 2.3734121168047446 1.6343265960902562e-11 0.4295473348819412 0.677703065502777 1.2485334785310083 1.2008910006150384 0.23743592419865453 2.7100597357540375 7.918134569267324e-06 5.101377121655093 -2.3734121167884012 MVAEVS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 MVAEVSPK 8 0 Q6S8J7-2;Q6S8J7 Q6S8J7-2 POTEA POTE ankyrin domain family member A 1 MVAEVS(1)PK 67.89699999999999 0.045071 4215700.0 35381.0 30534.0 27032.0 43858.0 36318.0 35385.0 34765.0 32422.0 32761.0 33848.0 True False 46631.42202948255 40403.51837508605 26673.538017604973 33747.21569934532 31275.872594312463 33172.37035623382 37859.017651271075 27411.924883441734 34492.67957709294 32662.99182252937 1.427653115270305 1.2369815537601072 0.8166287449273658 1.0331942610372913 0.9575323890795534 1.0155949747797783 1.159079910896519 0.8392349675859851 1.0560171512917422 1.0 14.995369322618116 -5.03248627404734 4.553206323105715 0.9874274403102068 1.3961222571780467 0.6964380637731482 0.09554801521063352 0.0941529453052634 4.701456478312695 0.023723535086129052 0.07994505487318486 9.279268169523816e-06 5.03248627404734 0.4086948168678399 MVEPENAVT(ph)ITPLRPEDDYSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MVEPENAVTITPLRPEDDYSPR 22 1 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;A0A669KAX5;H0YDF9 A0A0G2JMS7 SCRIB Protein scribble homolog 1 MVEPENAVT(0.612)IT(0.304)PLRPEDDY(0.055)S(0.029)PR 44.729 0.044956 5609100.0 8247.1 12938.0 15273.0 12856.0 23034.0 13799.0 11259.0 11564.0 14131.0 11696.0 True False 9643.171142350182 14222.399135736783 15637.166243175041 12135.719999714362 18520.653050952522 13075.356148248817 10192.46601189895 11260.457253070801 14337.639141774482 13816.392214514939 0.6979514617585522 1.0293858856145752 1.1317836089472961 0.8783566513814705 1.3404840253083925 0.9463654436874179 0.7377082130884473 0.815007063945465 1.0377267031194977 1.0 13.754093322791235 -6.997303557930302 24.999888372347282 0.8764575924814558 1.0280130033267503 0.08604724592844382 0.17436858034521024 170.980584402655 1585213.3035601128 0.06149323398520968 0.05392752113950466 1.0062281017862235e-07 6.997303557930302 0.15155541084529445 MVEPENAVT(ph)ITPLRPEDDYSPR ddPTM_PC-9_Lapatinib_30min_R1 1 MVEPENAVTITPLRPEDDYSPR 22 1 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;A0A669KAX5;H0YDF9 A0A0G2JMS7 SCRIB Protein scribble homolog 1 MVEPENAVT(0.399)IT(0.399)PLRPEDDY(0.073)S(0.13)PR 71.637 0.00099181 16050000.0 32355.0 39664.0 16423.0 15178.0 17554.0 12915.0 13911.0 16718.0 22459.0 11605.0 True False 31893.611766819686 39572.16044494892 15072.764334613286 16294.240752323716 16521.50823249185 12362.655556335454 14631.243512954234 17494.779312059578 19929.43091624533 13610.908787309509 2.343238961130688 2.907385617178264 1.1074032285534656 1.197145687106219 1.2138431379318417 0.9082902361275174 1.074964481915863 1.2853498311862392 1.4642248528494337 1.0 13.732475776969839 -5.2669597957936665 24.999847827853767 1.1583305924166096 2.6253123343105016 0.9030676877859783 0.19249848331168087 106.76135537366984 483483.1783858477 0.04982890225448021 0.10866552936727478 5.408043848404823e-06 5.2669597957936665 1.466981741893892 MVEPENAVTITPLRPEDDY(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MVEPENAVTITPLRPEDDYSPR 22 1 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;A0A669KAX5;H0YDF9 A0A0G2JMS7 SCRIB Protein scribble homolog 1 MVEPENAVT(0.001)IT(0.008)PLRPEDDY(0.793)S(0.198)PR 54.875 0.0087581 16284000.0 32817.0 32724.0 37281.0 28321.0 86866.0 29554.0 43330.0 27143.0 37277.0 31807.0 True False 38372.269934705015 35972.622454618235 38169.920428979814 26734.266187920835 69845.23087279857 28004.136213156442 39225.468717966185 26430.52501038572 37822.10560384453 37573.35731592653 1.021262742428392 0.9573970766612921 1.015877290603478 0.7115218893838045 1.8589031127967022 0.7453189763611062 1.0439702895897292 0.7034379384347003 1.006620337007057 1.0 15.19742241132992 -1.961505274129835 4.1018708636997605 1.0063709870461517 0.5536494064590926 0.0 0.31270250036422353 39936885.03379335 0.0 0.0715102945674808 0.0 0.01092684357404459 1.961505274129835 -0.45272158058705914 MVEPENAVTITPLRPEDDYS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MVEPENAVTITPLRPEDDYSPR 22 1 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;A0A669KAX5;H0YDF9 A0A0G2JMS7 SCRIB Protein scribble homolog 1 MVEPENAVT(0.002)IT(0.006)PLRPEDDY(0.008)S(0.985)PR 66.587 0.0041103 7236000.0 18158.0 20373.0 23743.0 17527.0 42537.0 16141.0 21559.0 21150.0 17095.0 15536.0 True False 21231.790763152443 22395.496799533583 24309.123165828933 16545.019013300687 34202.18020440946 15294.537545393452 19516.775446356623 20594.834910277365 17344.982034437387 18352.55381709166 1.156884811495791 1.2202932094756616 1.3245635135089453 0.9015104479842134 1.863619665430819 0.8333738016967269 1.063436491774825 1.1221781510918376 0.9450990966872456 1.0 14.16369321225799 MVINHLEK ddPTM_PC-9_Lapatinib_30min_R1 1 MVINHLEK 8 0 P50990-2;P50990;H7C4C8 P50990-2 CCT8 T-complex protein 1 subunit theta 0 76.064 0.02139 1968500.0 28587.0 23328.0 26608.0 28391.0 28908.0 24746.0 27074.0 24045.0 27647.0 26127.0 False True 28179.344137786244 23273.98544926804 24420.39294985024 30478.96884959962 27207.688275314704 23687.671265743484 28475.75924590061 25162.21848058814 24533.10372418338 30643.01713796084 0.9196008346997079 0.7595200350045173 0.796931739453229 0.994646470756367 0.8878919511358945 0.7730202009513935 0.9292740045047518 0.8211403716319097 0.800609927336155 1.0 14.903270732806968 -11.728430079943465 2.253633849284996 1.4265214655324083 0.8532450406268502 0.2646643674517781 0.07319223079797982 5931097.020778372 1329969.085766561 12864944.918513117 0.01851404460308128 1.8688305289212934e-12 11.728430079943465 -0.5732764249055581 MVIPNQPPLTAT(ph)KKST(ph)LK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MVIPNQPPLTATKKSTLK 18 2 C9JXK9;C9JUT4;A0A087WZF1;Q93052 C9JXK9 LPP Lipoma-preferred partner 2 MVIPNQPPLT(0.459)AT(0.528)KKS(0.035)T(0.978)LK 44.415 0.030944 47768000.0 70402.0 33251.0 49666.0 79632.0 72518.0 74421.0 71326.0 96228.0 66928.0 54115.0 True False 82319.66809711764 36551.93953179657 50850.225799353866 75170.47721042717 58308.61847481879 70518.23174931707 64569.484924478624 93702.11696199373 67906.69538466382 63925.62112589567 1.2877413883080866 0.5717885706548063 0.7954592369029782 1.175905308176604 0.9121322162828155 1.1031293948702956 1.0100720773180276 1.4657990851188754 1.0622766613550425 1.0 15.964106652863789 -6.6767007933420155 0.9998994745805821 1.1772826212260499 0.8934322001443522 0.12855168028535124 0.2215942366471009 0.8657378298555966 1.8678816166151577 0.12048665022520551 0.11979403396632733 2.1052283347721772e-07 6.6767007933420155 -0.28385042108169767 MVIQGPS(ph)SPQGEAMVTDVLEDQK ddPTM_PC-9_AZD4547_30min_R2 3 MVIQGPSSPQGEAMVTDVLEDQK 23 0 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 MVIQGPS(0.478)S(0.478)PQGEAMVT(0.044)DVLEDQK;MVIQGPS(0.498)S(0.498)PQGEAMVT(0.004)DVLEDQK;MVIQGPS(0.5)S(0.5)PQGEAMVTDVLEDQK 80.847 8.3842e-05 23844700.0 69006.0 94175.0 82501.0 79697.0 85350.0 99415.0 85371.0 111701.0 105877.0 85755.0 True False 90948.47258603398 124615.22705750084 81406.98283480418 61324.08795637565 73500.62574823976 93198.56433418061 92968.85361445881 94440.1770836261 111473.44206782042 82752.74355179064 1.099038759109105 1.5058742672321268 0.9837375697865023 0.7410520222570759 0.8881956367070724 1.1262292986800186 1.1234534303539367 1.141233184909705 1.3470664208015652 1.0 16.33651952280404 -10.025726115369512 15.96539323461463 1.0000356171723555 1.0993357993952284 0.022847513557853527 0.2039644016498667 0.0 0.0 0.2149475234146414 0.05213243194138188 9.424837796292701e-11 10.025726115369512 0.09930018222287296 MVIQGPS(ph)SPQGEAMVTDVLEDQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 MVIQGPSSPQGEAMVTDVLEDQK 23 0 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 MVIQGPS(0.556)S(0.444)PQGEAMVTDVLEDQK;MVIQGPS(0.606)S(0.394)PQGEAMVTDVLEDQK;MVIQGPS(0.499)S(0.499)PQGEAMVT(0.002)DVLEDQK;MVIQGPS(0.499)S(0.499)PQGEAMVT(0.002)DVLEDQK 91.337 8.961e-06 26423400.0 182955.0 283346.0 206481.0 200596.0 223808.0 138453.0 203547.0 127438.0 134670.0 148457.0 True False 213925.66797403633 311474.7183115223 211404.2901235529 189357.25646100647 179954.4290191713 131192.2809474234 184265.55460733548 124092.88753172202 136639.29397939087 175371.07891503465 1.2198457653196109 1.7760894227173474 1.2054683784318618 1.0797519045472028 1.0261351537123018 0.7480839016277285 1.050718030289419 0.7076017796061097 0.7791438293288433 1.0 17.420051321728458 -5.816002436549282 1.4045654721470153 0.8613806506912253 1.5038218182450305 0.652376498814114 0.17341242829075235 0.24134098692476214 0.9616367063289901 0.056488381137675514 0.12548150224145135 1.5275574880634633e-06 5.816002436549282 0.6424411675538052 MVIQGPS(ph)SPQGEAMVTDVLEDQK ddPTM_PC-9_Lapatinib_30min_R1 3 MVIQGPSSPQGEAMVTDVLEDQK 23 0 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 MVIQGPS(0.5)S(0.5)PQGEAMVTDVLEDQK;MVIQGPS(0.499)S(0.499)PQGEAMVT(0.003)DVLEDQK;MVIQGPS(0.5)S(0.5)PQGEAMVT(0.001)DVLEDQK 83.236 3.3686e-05 10653700.0 50866.3 75638.6 67732.9 66374.2 84278.6 69887.3 82026.5 84036.1 76719.1 71049.0 True False 50140.937234263 75463.46346892159 62164.16241855505 71255.58008584045 79321.49844610284 66898.38309425346 86273.43081125301 87940.72399486612 68078.18707006182 83329.72498315829 0.6017173012919094 0.9056007743236096 0.7460022510708995 0.8551039872055485 0.9518991987809206 0.8028153591983441 1.035325999560057 1.0553343841305098 0.8169736199635971 1.0 16.34654359826368 -3.4358929542565435 0.347209862537013 0.9798088122808841 1.5514126918042574e-16 0.4872010306175536 0.09632914843766453 14.881885476469696 0.6885775226530251 0.08494744560436779 7.3597816774454135 0.00036652790602168027 3.4358929542565435 -0.979808812280884 MVIQGPS(ph)SPQGEAMVTDVLEDQKEGR ddPTM_PC-9_AZD4547_30min_R2 9 MVIQGPSSPQGEAMVTDVLEDQKEGR 26 1 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 MVIQGPS(0.5)S(0.5)PQGEAMVTDVLEDQKEGR;MVIQGPS(0.553)S(0.42)PQGEAMVT(0.027)DVLEDQKEGR;MVIQGPS(0.498)S(0.498)PQGEAMVT(0.003)DVLEDQKEGR;MVIQGPS(0.333)S(0.333)PQGEAMVT(0.333)DVLEDQKEGR;MVIQGPS(0.499)S(0.499)PQGEAMVT(0.002)DVLEDQKEGR;MVIQGPS(0.5)S(0.5)PQGEAMVTDVLEDQKEGR;MVIQGPS(0.5)S(0.5)PQGEAMVTDVLEDQKEGR;MVIQGPS(0.5)S(0.5)PQGEAMVTDVLEDQKEGR;MVIQGPS(0.498)S(0.498)PQGEAMVT(0.004)DVLEDQKEGR 82.21600000000001 9.9995e-06 543696800.0 459477.2 400304.1 510999.1 782062.0 686590.0 599307.0 468308.5 556849.0 515279.0 598230.0 True False 605581.3918805277 529694.5719516703 504222.9180531196 601769.6886374535 591268.8299060783 561832.2385497649 509987.04926622385 470800.7821670363 542515.5959770727 577286.1497870417 1.0490142403449727 0.917559813529343 0.8734367145983413 1.0424114433707505 1.024221402374186 0.973230067544531 0.8834215916220333 0.8155414474099416 0.9397689450495292 1.0 19.138927087149135 -7.253860895316672 20.700364400700597 0.8943114435922 0.9771477957575788 0.19270697336375386 0.06746990173674232 81.2137976906995 221834.63959110086 0.02685387791537738 0.020277004643516332 5.573642443181243e-08 7.253860895316672 0.08283635216537877 MVIQGPS(ph)SPQGEAMVTDVLEDQKEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 MVIQGPSSPQGEAMVTDVLEDQKEGR 26 1 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 MVIQGPS(0.5)S(0.5)PQGEAMVT(0.001)DVLEDQKEGR;MVIQGPS(0.5)S(0.5)PQGEAMVTDVLEDQKEGR;MVIQGPS(0.499)S(0.499)PQGEAMVT(0.001)DVLEDQKEGR;MVIQGPS(0.489)S(0.489)PQGEAMVT(0.021)DVLEDQKEGR;MVIQGPS(0.333)S(0.333)PQGEAMVT(0.333)DVLEDQKEGR;MVIQGPS(0.471)S(0.471)PQGEAMVT(0.059)DVLEDQKEGR 74.222 4.3073e-05 373637800.0 435940.0 334021.0 389205.0 531838.0 511597.0 520903.0 490203.0 439836.0 433801.0 381458.0 True False 509736.03179252543 367180.39741211425 398485.12326818216 502040.8411020605 411353.2403797929 493585.9296826763 443767.4230776186 428290.7710447633 440144.5189541362 450613.3157801344 1.1312049909355952 0.8148458657428376 0.8843172390019053 1.1141278420343417 0.9128741339292834 1.0953647226960983 0.984807611176195 0.950461861747861 0.9767676709511482 1.0 18.781530420780065 -5.705625595314409 24.999971344291186 1.0019492408714552 0.9305951407168753 0.07682535260230261 0.09413373041117391 200.62271001537667 89860.31614268562 0.02454524453081318 0.0425135770191208 1.9695835333067924e-06 5.705625595314409 -0.07135410015457988 MVIQGPS(ph)SPQGEAMVTDVLEDQKEGR ddPTM_PC-9_Lapatinib_30min_R1 9 MVIQGPSSPQGEAMVTDVLEDQKEGR 26 1 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 MVIQGPS(0.484)S(0.484)PQGEAMVT(0.032)DVLEDQKEGR;MVIQGPS(0.484)S(0.484)PQGEAMVT(0.032)DVLEDQKEGR;MVIQGPS(0.499)S(0.499)PQGEAMVT(0.002)DVLEDQKEGR;MVIQGPS(0.5)S(0.5)PQGEAMVT(0.001)DVLEDQKEGR;MVIQGPS(0.856)S(0.144)PQGEAMVTDVLEDQKEGR;MVIQGPS(0.5)S(0.5)PQGEAMVTDVLEDQKEGR;MVIQGPS(0.5)S(0.5)PQGEAMVTDVLEDQKEGR;MVIQGPS(0.497)S(0.497)PQGEAMVT(0.005)DVLEDQKEGR;MVIQGPS(0.499)S(0.499)PQGEAMVT(0.002)DVLEDQKEGR 96.708 6.110800000000001e-09 181105900.0 479966.0 329746.0 367728.0 310990.0 340599.0 353329.0 301129.0 315128.0 364504.0 286359.0 True False 473121.59682501515 328982.4933965339 337494.8233111301 333861.2420322285 320565.63646339794 338217.9423201273 316719.9861844871 329769.99731132353 323449.72112271603 335855.7716006176 1.4087046787084159 0.9795350302562105 1.0048802249331643 0.9940613509219043 0.9544741033797034 1.0070332890462237 0.9430238005887664 0.9818797984018838 0.9630613747717451 1.0 18.357482295928627 -4.761378313378576 24.99957117376577 0.9802874550444309 1.4087051466643281 0.9748298837944478 0.020623282743997783 0.19251382017421562 78183.64082966377 0.004979296838052001 0.027848461605200624 1.732294340891465e-05 4.761378313378576 0.4284176916198972 MVIQGPSS(ph)PQGEAMVTDVLEDQKEGR ddPTM_PC-9_AZD4547_30min_R2 2 MVIQGPSSPQGEAMVTDVLEDQKEGR 26 1 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 MVIQGPS(0.204)S(0.796)PQGEAMVT(0.001)DVLEDQKEGR;MVIQGPS(0.247)S(0.753)PQGEAMVTDVLEDQKEGR 84.68 2.133e-06 12270400.0 46264.6 44108.4 63583.0 82275.0 69455.0 69789.0 49293.6 63129.0 54595.0 57639.0 True False 60975.780436539346 58365.57771322614 62739.84787560585 63307.769886078604 59812.37213056807 65425.082797547024 53680.63490564349 53373.86361010408 57480.78024209847 55621.076153946204 1.0962711377207548 1.049342834570187 1.1279869469255959 1.1381975010849739 1.0753544567354527 1.1762642386937212 0.9651132020004068 0.9595978233570606 1.033435241040735 1.0 15.763344037699383 -7.275536936829614 24.99765842531277 0.9861697102959333 1.1082333230318373 0.7120898668717734 0.03766061738394304 442.6387432700179 784879.8970357949 0.015722319954075557 0.01065909868711789 5.302284946755075e-08 7.275536936829614 0.12206361273590405 MVIQGPSS(ph)PQGEAMVTDVLEDQKEGR ddPTM_PC-9_Lapatinib_30min_R1 4 MVIQGPSSPQGEAMVTDVLEDQKEGR 26 1 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 MVIQGPS(0.267)S(0.729)PQGEAMVT(0.004)DVLEDQKEGR;MVIQGPS(0.217)S(0.728)PQGEAMVT(0.055)DVLEDQKEGR;MVIQGPS(0.231)S(0.769)PQGEAMVTDVLEDQKEGR;MVIQGPS(0.171)S(0.828)PQGEAMVT(0.001)DVLEDQKEGR 98.95700000000001 4.7138e-09 95728700.0 419629.0 309352.0 355441.0 289157.0 316956.0 352140.0 291495.0 289551.0 332577.0 249542.0 True False 413645.01350946625 308635.71445053077 326218.01302193844 310422.5703794745 298313.27123947215 337079.7930784331 306587.1848040107 303004.59651789506 295118.67606893106 292675.0022061865 1.413325396400126 1.0545339100505076 1.1146083900671546 1.060639166445739 1.0192646074682987 1.1517204767661158 1.0475345775790694 1.0352937361709884 1.0083494450989123 1.0 18.15894000278248 -4.760948878182739 24.99999998952459 1.0595279115303802 1.4133257969527895 0.8519986306787904 0.044804668860700086 4.251863545359746 216494.50986012767 0.011106917992235597 0.06376390437535723 1.734008099882456e-05 4.760948878182739 0.3537978854224093 MVIQGPSSPQGEAMVT(ph)DVLEDQKEGR ddPTM_PC-9_Lapatinib_30min_R1 1 MVIQGPSSPQGEAMVTDVLEDQKEGR 26 1 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 MVIQGPS(0.301)S(0.301)PQGEAMVT(0.399)DVLEDQKEGR 43.88399999999999 0.015844999999999998 77297000.0 55024.0 43483.0 47592.0 44203.0 36978.0 37610.0 38490.0 43053.0 46015.0 36694.0 True False 54239.34766983422 43382.31778508756 43679.1694704327 47453.83607688531 34803.026741545174 36001.50797319213 40482.8238669836 45053.399552703704 40832.30614056853 43036.50900831836 1.2603101162166872 1.0080352422800454 1.0149329134012735 1.1026413891450428 0.8086861026487588 0.8365341149356128 0.9406623538902477 1.0468646409957534 0.9487829538561366 1.0 15.393273435124014 -1.5228787452817583 0.8345725213548579 0.9459475163982646 97.34202299669315 0.5349618972786536 0.08355906444890261 516.9088797433091 1.5451561667287852 0.031440201369268866 94489.1961720265 0.029999999999901862 1.5228787452817583 96.39607548029488 MVIS(ph)NIFNTDY(ph)HMNLR ddPTM_PC-9_AZD4547_30min_R2 1 MVISNIFNTDYHMNLR 16 0 Q5VSJ8;E7EU00;F6XSS0;P18577-14;P18577-9;P18577-8;P18577-7;P18577-2;P18577-5;P18577-6;P18577 Q5VSJ8 RHCE Blood group Rh(CE) polypeptide 2 MVIS(0.937)NIFNT(0.078)DY(0.985)HMNLR 40.278 0.032326 518610.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MVPPVVVGS(ph)PPGS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 1 MVPPVVVGSPPGSPSR 16 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 2 MVPPVVVGS(1)PPGS(0.969)PS(0.031)R 82.12100000000001 0.024678 0.0 19243.0 18137.0 16481.0 15714.0 16739.0 17522.0 11934.0 12022.0 18263.0 12894.0 True False 18968.591291265995 18095.00489083397 15125.995798499769 16869.659980367316 15754.444930140211 16772.624905776986 12551.884126489535 12580.586008468721 16206.028622084157 15122.71071982497 1.2543115875647417 1.1965450656351244 1.000217228163367 1.1155182620965036 1.0417738738787798 1.1091017487882695 0.8300022634192668 0.8319001957748438 1.0716351666265111 1.0 13.884429142886933 -4.058459095385258 0.39850461765201256 0.9376472580700522 1.7305808697316871 0.5101083355488868 0.09185931565197113 8.345941277349649 0.6715663598427001 0.0758563925815906 3.53780621351814 8.740593131755483e-05 4.058459095385258 0.7929336116616349 MVPPVVVGS(ph)PPGSPSR ddPTM_PC-9_AZD4547_30min_R2 3 MVPPVVVGSPPGSPSR 16 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 MVPPVVVGS(0.983)PPGS(0.015)PS(0.002)R;MVPPVVVGS(0.755)PPGS(0.237)PS(0.008)R;MVPPVVVGS(0.676)PPGS(0.305)PS(0.02)R 135.61 7.1897e-06 21920000.0 66402.8 70333.3 88565.0 113806.0 107285.0 92591.4 77801.0 99337.0 80792.1 88412.0 True False 87517.50913595773 93067.16378235546 87390.57023265709 87569.7849851724 92390.32962390048 86801.64512087574 84725.13827949195 83986.74918717066 85062.60546565875 85316.72279051822 1.0257954862007908 1.0908431634307758 1.0243076313096422 1.0264082130790024 1.082909968901998 1.0174048214908993 0.99306601927879 0.9844113374277971 0.9970214828166406 1.0 16.380540929092525 -6.985349120600599 5.928271708057871 0.9938493861250893 1.0498253145836351 0.6022308808564285 0.021681915315655297 0.11128162843679312 14.059053105429289 0.007817177778068729 0.006661628446635907 1.0343103710843115e-07 6.985349120600599 0.05597592845854582 MVPPVVVGS(ph)PPGSPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 MVPPVVVGSPPGSPSR 16 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 MVPPVVVGS(0.99)PPGS(0.01)PSR;MVPPVVVGS(0.966)PPGS(0.027)PS(0.007)R;MVPPVVVGS(0.946)PPGS(0.051)PS(0.003)R 105.63 0.0029905 20823500.0 104328.0 93351.2 111135.9 131008.0 137972.0 123009.0 121724.0 127583.0 120018.0 92700.9 True False 121988.66982807394 102618.49019941188 113785.8013412478 123668.04649366636 110937.37704028937 116558.1914950316 110193.42151455616 124234.08143536228 121773.03619825136 109506.8393500795 1.1139822001262552 0.9370966307533867 1.0390748378508943 1.129318015455777 1.0130634552024336 1.0643918880939465 1.0062697651448211 1.134486961478284 1.1120130662246435 1.0 16.74066145191903 -7.7570736269697695 24.98562863969644 1.092437507360116 1.0420205882556894 0.07109606867391316 0.060934556038283544 228.94525571869255 1310301.3143089414 0.029097338025887792 0.016025539209826727 1.749550058125533e-08 7.7570736269697695 -0.05041691910442658 MVPPVVVGS(ph)PPGSPSR ddPTM_PC-9_Lapatinib_30min_R1 2 MVPPVVVGSPPGSPSR 16 0 E9PIR9;E7ET48;Q8N1P7 E9PIR9 AIM1L Absent in melanoma 1-like protein 1 MVPPVVVGS(0.902)PPGS(0.091)PS(0.006)R;MVPPVVVGS(0.63)PPGS(0.325)PS(0.045)R 96.48899999999999 0.0020415 20391000.0 105707.0 87017.0 99143.0 82568.0 89183.0 100963.0 84120.0 82315.0 103131.0 70642.0 True False 104199.59879571022 86815.51748280847 90991.84524304727 88640.3261587735 83937.43128052418 96645.0478462483 88475.32199767885 86139.65540568151 91515.30076242473 82852.37557545186 1.2576537253396904 1.0478337751914846 1.0982406311353494 1.0698585954008124 1.013096253396913 1.1664728642359294 1.067867051284562 1.0396763497413057 1.1045585612579536 1.0 16.338255443101062 -4.7570639717928165 24.995450475671774 1.0711882439777456 1.2576540022884262 0.6077966667415458 0.0457364738313516 87.71876693602327 501048.37116687594 0.010852727782482856 0.08320949757564315 1.7495889543212654e-05 4.7570639717928165 0.18646575831068057 MVS(ph)PLRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MVSPLRR 7 1 Q53ET0;H0YDQ8 Q53ET0 CRTC2 CREB-regulated transcription coactivator 2 1 MVS(1)PLRR 62.582 0.024712 2366000.0 3834.5 3603.8 4378.4 5088.3 6481.4 4481.2 5006.4 5804.0 4291.7 4803.6 True False 4483.6051151728225 3961.5614473155215 4482.797661174468 4803.219047491175 5211.4161971192 4246.197983298255 4532.157548802816 5651.651149846325 4354.457993401283 5674.454654723319 0.7901385045769546 0.6981395902103095 0.7899962082599539 0.8464635528443349 0.9183994787554264 0.7483006282839518 0.7986948217182994 0.9959813750810375 0.7673791154145018 1.0 12.47026603306013 -13.475191169733236 0.027914763662794825 2.102441179348296 1.8807379179921528e-06 0.3878169757583543 0.07682156279323016 1432.3362723915923 3.5830381949048093 191.14867107091808 94.05035922679185 3.3481802498445685e-14 13.475191169733236 -2.102439298610378 MVSNSCTQAILPPQPPK ddPTM_PC-9_Lapatinib_30min_R1 1 MVSNSCTQAILPPQPPK 17 0 E5RIU9 E5RIU9 CHMP7 0 54.598 0.037344999999999996 45816000.0 46019.0 44961.0 52195.0 45952.0 52006.0 45605.0 43153.0 45571.0 49995.0 42688.0 False True 45362.760621148955 44856.8955668956 47903.72857852649 49331.4633713783 48947.10932772996 43654.58046044742 45387.25119074936 47688.39502511467 44364.03662931049 50066.563921815425 0.9060490089151716 0.8959451588677962 0.9568008032932629 0.9853175354397185 0.9776406746060381 0.8719308265016741 0.9065381690987754 0.9524998579807766 0.8861010853189352 1.0 15.611559825922578 -7.657078295614272 0.0044753862025982225 1.8729816659813576 1.01500929264138e-07 0.09109315010691166 0.041431900595873726 21879.62751427995 86.74194099824243 18094.91424921416 18201.48371954944 2.2025293501698218e-08 7.657078295614272 -1.8729815644804284 MVSQS(ph)QPGSR ddPTM_PC-9_Lapatinib_30min_R1 2 MVSQSQPGSR 10 0 E3W994;J3KR49;O75122;E7ERI8;E7EW49;O75122-3 E3W994;E7ERI8 CLASP2 CLIP-associating protein 2 1 MVSQS(0.783)QPGS(0.217)R;MVS(0.051)QS(0.598)QPGS(0.35)R 110.93 0.0016683 12064100.0 32632.0 26896.0 33143.0 24492.0 29894.0 27043.0 24576.0 29134.0 34104.0 25274.0 True False 32166.661696024115 26833.723964485318 30418.110475679743 26293.223382916887 28135.69369386531 25886.433930312014 25848.425028708465 30487.67199889601 30262.848388959006 29642.577224511864 1.0851506416731218 0.9052426096842934 1.0261628145654818 0.8870086829418682 0.9491648948324071 0.8732855356755606 0.8720032955614277 1.0285094905204573 1.0209250079623384 1.0 14.855383265364036 -7.794048079048669 24.99598725081084 1.0185380387244465 0.9398045843823417 0.21304077451271397 0.0649025199149709 298.57120613892283 228864.01754145708 0.03517732037080667 0.016900470954907775 1.6067633646594655e-08 7.794048079048669 -0.07873345434210477 MVSQSQPGS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 MVSQSQPGSR 10 0 E3W994;J3KR49;O75122;E7ERI8;E7EW49;O75122-3 E3W994;E7ERI8 CLASP2 CLIP-associating protein 2 1 MVS(0.001)QS(0.044)QPGS(0.956)R 87.641 0.010498 3704500.0 7876.0 8567.3 8863.3 11642.0 7181.1 10422.0 7247.1 9962.5 6661.9 8336.7 True False 10380.404169023052 11336.512182317252 8745.766850822656 8958.116767106989 6184.128219808835 9770.310692459214 7892.077860507024 8423.024540475251 7014.034433461592 8044.834670493996 1.2903191419328 1.4091665828629303 1.087128226873259 1.1135240354861031 0.7687079316235464 1.214482471379274 0.9810118148795229 1.0470102724880526 0.8718680645093845 1.0 12.973847057070184 -5.448388169368732 2.3301788588488117 0.9986075194511694 1.354646037470513 0.5689162682913235 0.11914984259887745 0.21198877775583674 2.223458815373661 0.03238096460826685 0.0847804169621219 3.5613268223355697e-06 5.448388169368732 0.3560385180193435 MVVESAYEVIK ddPTM_PC-9_Lapatinib_30min_R1 2 MVVESAYEVIK 11 0 A0A5F9ZHM4;P07195;A0A3B3IS95 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain 0 ; 203.4 3.7742e-05 21529000.0 91642.0 73702.0 94831.0 78589.0 87860.0 89414.0 86314.0 76333.0 68746.0 84279.0 False True 90335.16827491524 73531.34754723731 87034.36123824595 84368.6972252185 82692.24753940606 85589.97165421433 90782.91658235446 79879.70984731696 61003.10155252685 98846.51285529131 0.9138933247666869 0.7438941994330671 0.880500067469876 0.8535323582808838 0.8365722285060813 0.8658876189139397 0.9184230577284831 0.8081186431357346 0.6171497586549541 1.0 16.592902450459746 -10.718361345764196 4.41730759512444 1.000041183153237 0.8300247630796571 0.27134137251690293 0.08514205241943557 121249032.86703129 5.161384300515616 58562.617686253485 0.020441630982749263 1.9126638702796653e-11 10.718361345764196 -0.17001642007357987 MVVS(ph)IAEDLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 MVVSIAEDLLR 11 0 Q9P2D3;Q9P2D3-2;Q9P2D3-3 Q9P2D3 HEATR5B HEAT repeat-containing protein 5B 1 MVVS(1)IAEDLLR;MVVS(1)IAEDLLR 52.167 0.039602 1963110.0 4477.05 5116.4 5704.8 5392.7 6421.0 3527.99 6267.200000000001 5618.8 3956.2 3832.0 True False 5234.926139231837 5624.322378890378 5840.824067574483 5090.56450236929 5162.851143534174 3342.9759937285594 5673.525445401283 5471.3124536107025 4014.0519406049266 4526.71126590469 1.156452406996099 1.2424742928167132 1.2903018824212902 1.124561343399911 1.1405302525966052 0.7384999389972018 1.2533437880463965 1.2086727277749685 0.8867479511756964 1.0 12.144247572574978 -6.1520444687289695 2.500480878506124 1.0417082165597193 1.2271451346385973 0.2599852930923273 0.1447805017906817 0.4413339123205354 5.392280498978007 0.04735832579667952 0.06474198810945594 7.046209170008757e-07 6.1520444687289695 0.18543691807887797 MWNRS(ph)FQGVTGY(ph)LK ddPTM_PC-9_Lapatinib_30min_R1 1 MWNRSFQGVTGYLK 14 1 P16066 P16066 NPR1 Atrial natriuretic peptide receptor 1 2 MWNRS(0.999)FQGVT(0.023)GY(0.978)LK 53.869 0.037438 3804400.0 19179.0 17387.0 16572.0 14873.0 20871.0 15281.0 16219.0 13232.0 15689.0 14215.0 True False 18905.503943002146 17346.741469754106 15209.514129769936 15966.810034873559 19643.408813964772 14627.467251750833 17058.74045982352 13846.807025790908 13921.939607505798 16672.04380970312 1.1339643872576173 1.0404688032104568 0.9122765213055647 0.9576996208215868 1.1782243999702258 0.8773649720880446 1.023194315857984 0.8305404654546358 0.8350469664315084 1.0 14.025143353302884 -7.342664579752605 1.5968417393654613 0.88468373302312 1.025926694263169 0.24340178918546496 0.09836151530615092 0.5520530937933835 2.7340590275159586 0.05858538153938799 0.033025688813217526 4.542923464639024e-08 7.342664579752605 0.1412429612400491 MWNST(ph)FQTY(ph)KK ddPTM_PC-9_Lapatinib_30min_R1 1 MWNSTFQTYKK 11 1 H3BMH7 H3BMH7 2 MWNS(0.048)T(0.945)FQT(0.117)Y(0.89)KK 62.693999999999996 0.024944 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1701.5 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1509.8591524106787 0.0 0.0 MY(ph)HICFFLVTYMAPLCLMVLAYLQIFRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MYHICFFLVTYMAPLCLMVLAYLQIFRK 28 1 O43614 O43614 HCRTR2 Orexin receptor type 2 1 MY(0.996)HICFFLVT(0.002)Y(0.002)MAPLCLMVLAYLQIFRK 41.49100000000001 0.035476 2148500.0 2702.2 3292.0 4645.9 5253.8 4394.8 5794.8 5509.5 5848.4 4100.9 4699.8 True False 3159.6290891172234 3618.808003929936 4756.675875673865 4959.446619049419 3533.6704883357716 5490.910486837616 4987.600274674237 5694.885696892016 4160.867904359418 5551.836536403668 0.569114214440461 0.6518217854940851 0.8567752030313042 0.8932983863141648 0.6364867670662345 0.989025964801637 0.8983694390082082 1.0257660973175935 0.7494579274941545 1.0 12.438749375706589 -4.064342321330079 0.4895635649903818 0.9214639618883785 6.679159217931565e-22 0.5002451463246396 0.11078022387002143 7.606887386082837 0.8270798000974052 0.06700581745423521 4.679839222210241 8.622985953839332e-05 4.064342321330079 -0.9214639618883785 MYASVLLITAMS(ph)LDR ddPTM_PC-9_AZD4547_30min_R2 1 MYASVLLITAMSLDR 15 0 G3V4Q5 G3V4Q5 LTB4R 1 MYASVLLIT(0.034)AMS(0.966)LDR 90.149 0.0037959000000000005 6070400.0 23429.0 18256.0 24647.0 41073.0 32947.0 35461.0 27347.0 37503.0 20723.0 29212.0 True False 30878.93464652632 24156.89498446227 24320.164675936292 31604.254421524256 28372.877756616905 33243.61806421952 29780.83002184123 31707.773083206353 21818.37547315701 28189.296771440797 1.0954134435098946 0.8569527356544827 0.8627446393262137 1.1211437687776316 1.0065124357895334 1.1792993040500168 1.0564587780711454 1.1248160371042035 0.7739950254900183 1.0 14.782859867496464 -4.463510989018378 22.467643387966916 1.0073267299206523 2.9954751768913765 0.04715343017879048 0.1252042041853316 1170.7343085956434 569931.9151438519 0.030818507882651974 32952.28190314784 3.439450083784281e-05 4.463510989018378 1.9881484469707242 MYFPDVEFDIKS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 MYFPDVEFDIKSPK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 MYFPDVEFDIKS(1)PK;MYFPDVEFDIKS(1)PK;MYFPDVEFDIKS(1)PK 98.508 0.0052882 4888600.0 74484.0 53473.1 41703.8 61320.0 82723.0 82004.0 104009.0 144158.0 83697.0 87105.0 True False 87092.6700739425 58781.55597659352 42698.17675454222 57884.43920212228 66514.02198202428 77703.56588020851 94156.5145600494 140374.00524802663 84920.91028583261 102896.44697719958 0.8464108589992522 0.5712690545050472 0.41496259597771673 0.5625504174594937 0.6464170915130127 0.755162769589377 0.9150608920530868 1.3642259705928579 0.8253045929238927 1.0 16.650833641150008 -7.183126878290967 2.027480387453956 1.075664670426562 0.5934638709657418 0.6000772350146162 0.1619674935858703 0.21446598348519957 1.7268423723146094 0.07779057343137119 0.052803387884503485 6.559536027337885e-08 7.183126878290967 -0.4822007994608202 MYPES(ph)TTGSPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MYPESTTGSPAR 12 0 A0A590UJ15;A0A590UJK5;A0A5F9UN28;A0A590UJJ4;K7EKU4;K7EIR5;A0A590UJU4;Q5TG84;A0A590UJU1;A0A590UJY1;A0A590UK89;Q5TG78;A0A590UJX9;A0A590UJV4;A0A590UJ72;A0A590UJI8;Q13303-2;Q13303;Q13303-5 A0A590UJ15 KCNAB2 Voltage-gated potassium channel subunit beta-2 1 MY(0.001)PES(0.354)T(0.354)T(0.2)GS(0.09)PAR 72.34 0.022246000000000002 6011400.0 31719.0 27112.0 29749.0 35834.0 35361.0 32961.0 34715.0 28892.0 26707.0 23039.0 True False 37088.400221193544 29803.500183034143 30458.328983710755 33826.3371553955 28432.265891062434 31232.467135475705 31426.543885164938 28133.6156136044 27097.539350319956 27215.78832337635 1.3627531115583138 1.0950812752109458 1.1191418974092073 1.2428938950242048 1.0446974951903643 1.1475863482025 1.154717383592077 1.0337240751332455 0.9956551332758997 1.0 14.732156204837297 -1.5228787452833192 0.16134120301153118 0.9716365443290664 2.0722258648297243 0.5244414334751918 0.07541488573527745 56.72881753498593 0.5911722099610836 0.22444708862037857 14.863929305679076 0.02999999999979403 1.5228787452833192 1.1005893205006578 MYPESTTGS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 1 MYPESTTGSPAR 12 0 A0A590UJ15;A0A590UJK5;A0A5F9UN28;A0A590UJJ4;K7EKU4;K7EIR5;A0A590UJU4;Q5TG84;A0A590UJU1;A0A590UJY1;A0A590UK89;Q5TG78;A0A590UJX9;A0A590UJV4;A0A590UJ72;A0A590UJI8;Q13303-2;Q13303;Q13303-5 A0A590UJ15 KCNAB2 Voltage-gated potassium channel subunit beta-2 1 MYPES(0.009)T(0.009)T(0.158)GS(0.825)PAR 94.402 0.0043325 4018300.0 14337.0 13386.0 13915.0 23327.0 21734.0 20554.0 13989.0 19467.0 16394.0 20248.0 True False 18895.86777187451 17712.76272250286 13730.478008100521 17949.320548557364 18716.6092561481 19268.75513076247 15233.99389971612 16458.822457157497 17260.553370985668 19539.12368301155 0.9670785690508565 0.906528000429383 0.7027171858295056 0.9186348804457156 0.9579042315199329 0.9861627083877793 0.7796661788349004 0.8423521302271992 0.8833842116467586 1.0 14.25407814437245 -4.85491945241846 4.8718427471080235 0.8775758405210499 0.965975397322934 0.07003839048548632 0.08751537113717686 0.5002711407798582 18.369677748456176 0.02245750103765938 0.10834556437976045 1.3966273662469033e-05 4.85491945241846 0.08839955680188416 MYPESTTGS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 1 MYPESTTGSPAR 12 0 A0A590UJ15;A0A590UJK5;A0A5F9UN28;A0A590UJJ4;K7EKU4;K7EIR5;A0A590UJU4;Q5TG84;A0A590UJU1;A0A590UJY1;A0A590UK89;Q5TG78;A0A590UJX9;A0A590UJV4;A0A590UJ72;A0A590UJI8;Q13303-2;Q13303;Q13303-5 A0A590UJ15 KCNAB2 Voltage-gated potassium channel subunit beta-2 1 MYPES(0.041)T(0.041)T(0.171)GS(0.747)PAR 76.24 0.016617 2650100.0 26035.0 21650.0 29184.0 25630.0 27105.0 22623.0 20717.0 25629.0 26243.0 21277.0 True False 25663.73612576572 21599.870755172036 26784.60417349779 27514.91569917361 25510.737190480348 21655.467026788774 21789.62489094047 26819.816903264425 23287.236988958815 24954.701100179613 1.028412883918734 0.8655631926209114 1.0733289918389368 1.1025944806437922 1.0222818172843886 0.8677910803200487 0.8731671360625369 1.0747400578190611 0.9331803613063995 1.0 14.607024003329904 MYRS(ph)S(ph)ARS(ph)SVSS(ph)HR ddPTM_PC-9_AZD4547_30min_R2 1 MYRSSARSSVSSHR 14 2 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 4 MY(0.158)RS(0.838)S(0.969)ARS(0.849)S(0.204)VS(0.447)S(0.535)HR 69.729 0.02065 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MYRSS(ph)ARS(ph)S(ph)VS(ph)SHR ddPTM_PC-9_AZD4547_30min_R2 1 MYRSSARSSVSSHR 14 2 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 4 MYRS(0.017)S(0.994)ARS(0.995)S(0.995)VS(0.567)S(0.432)HR 76.156 0.011865 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MYTIIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 MYTIIK 6 0 A0A1W2PS44 A0A1W2PS44 0 63.67100000000001 0.031426 993990.0 1078.3 1228.3 2482.8 3919.8 2668.4 4024.4 2237.8 2996.8 3159.3 1053.2 False True 1260.8348926042127 1350.237506448099 2541.9993680714333 3700.1863141630633 2145.5461752696756 3813.3533794486966 2025.8193837310116 2918.137175372065 3205.4987856916086 1244.1368228733872 1.0134214094654481 1.0852805588774936 2.0431831301324053 2.974099187593632 1.7245259008687202 3.065059492927469 1.6282930835953355 2.345511459609806 2.5764841348304217 1.0 10.280929437997498 -5.293744558827378 4.199534795398527 2.253768554999124 1.0262932409128436 0.3594398675270192 0.5952414422650146 0.1863063581895898 7.634452446848572 0.14574614733014096 0.35158337665282835 5.08458417175175e-06 5.293744558827378 -1.2274753140862804 NAASFPLRS(ph)PQPVCSPAGSEGT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 NAASFPLRSPQPVCSPAGSEGTPK 24 1 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 2 NAAS(0.022)FPLRS(0.97)PQPVCS(0.016)PAGS(0.135)EGT(0.857)PK 73.126 0.0015302999999999998 5205100.0 35027.0 38190.0 44583.0 63337.0 44921.0 40797.0 41766.0 54480.0 41356.0 48602.0 True False 46164.85739314002 50534.17065384612 43991.80028998528 48735.63319689535 38684.49454290184 38245.957140688784 45483.09308853699 46061.367825856105 43541.99373005264 46900.45877329746 0.984315689027412 1.0774771073799707 0.9379823021055774 1.0391291358677015 0.8248212395936447 0.8154708533994965 0.9697792788848487 0.9821091100303034 0.9283916377134259 1.0 15.517314414586988 -6.233506553831242 24.994478733257736 0.9164537611840421 1.0094408707151437 0.30323764613321014 0.06642192610785065 968.4799671686987 866602.4283484601 0.020687906368499397 0.026701313650175522 5.841083923901909e-07 6.233506553831242 0.09298710953110156 NAASFPLRS(ph)PQPVCSPAGSEGTPK ddPTM_PC-9_AZD4547_30min_R2 2 NAASFPLRSPQPVCSPAGSEGTPK 24 1 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 NAAS(0.031)FPLRS(0.969)PQPVCSPAGSEGTPK;NAAS(0.001)FPLRS(0.999)PQPVCSPAGSEGTPK 124.96 2.3681999999999997e-09 53883000.0 73387.0 68724.0 84611.0 118885.0 89685.0 79304.0 82436.0 93886.0 89255.0 86461.0 True False 96722.53945557323 90937.68902893228 83489.0028561548 91477.9000049403 77233.78582578638 74345.10834338747 89772.64430030725 79378.07598565213 93972.83708230595 83434.02670668006 1.159269704141335 1.089935277229661 1.0006589176100538 1.0964099854192488 0.9256869034657624 0.8910646085050467 1.0759716130675459 0.9513873310311752 1.126313097804521 1.0 16.348348254220113 -4.7515230532709705 1.0905660996347353 0.9996328853832207 1.249710408994584 0.320116088122393 0.07102633185408577 2.174848840345367 2.032656560240651 0.02255096210064523 0.6420117640487302 1.7720539782599843e-05 4.7515230532709705 0.2500775236113634 NAASFPLRS(ph)PQPVCSPAGSEGTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NAASFPLRSPQPVCSPAGSEGTPK 24 1 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 NAAS(0.012)FPLRS(0.986)PQPVCS(0.002)PAGSEGTPK;NAAS(0.036)FPLRS(0.964)PQPVCSPAGSEGTPK 79.455 7.378300000000001e-05 18485700.0 26995.0 26921.4 25175.0 42424.0 45270.0 38397.0 47620.0 39598.0 36984.0 36728.0 True False 31564.720324446553 29593.97867466567 25775.267476719167 40047.12082046374 36399.66847341413 36383.393725944654 43109.08886105583 38558.59445754908 37524.82103314611 43386.49566131199 0.7275240796318337 0.6821011520654987 0.5940850276991404 0.9230319298678461 0.8389630902103934 0.838587979309607 0.993606148732968 0.8887234119701449 0.864896333782662 1.0 15.404958443551164 -5.769457920401046 24.999997317570628 0.9001378318707186 0.6693231857718419 0.761979377821902 0.061112475844203075 82.62146560516274 257595.55391514895 0.01723208388973132 0.026075553594207865 1.7003646971546208e-06 5.769457920401046 -0.2308146460988767 NAASFPLRS(ph)PQPVCSPAGSEGTPK ddPTM_PC-9_Lapatinib_30min_R1 2 NAASFPLRSPQPVCSPAGSEGTPK 24 1 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 NAAS(0.01)FPLRS(0.99)PQPVCSPAGSEGTPK;NAAS(0.006)FPLRS(0.992)PQPVCS(0.002)PAGSEGTPK 125.45 6.5895e-08 37022000.0 33533.3 38622.0 35872.0 35699.0 37570.0 34779.0 42572.0 37877.0 32683.0 32101.0 True False 33055.10899274594 38532.57313192863 32922.74262992436 38324.42354837297 35360.206465461924 33291.58324380878 44776.16985360418 39636.90369678672 29001.89637275237 37649.61507810618 0.8779667182299556 1.0234519809031435 0.8744509754382438 1.0179233829845766 0.9391917126404944 0.884247639046072 1.1892862585902557 1.0527837698886908 0.7703105679191236 1.0 15.20034749470572 NADDDRGPR ddPTM_PC-9_AZD4547_30min_R2 1 NADDDRGPR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 78.264 0.02833 3669900.0 6620.5 3451.2 4322.8 5250.0 4032.3 4992.8 2720.2 4438.6 4883.2 7357.7 False True 8725.68128504535 4566.732908105621 4265.476847532659 4039.6936116914344 3472.4847475644597 4680.599426723307 2962.292530274346 3752.716358881148 5141.315982749619 7100.109162509583 1.2289502999642892 0.6431919289662693 0.6007621502575597 0.5689621834298075 0.4890748392855816 0.6592292202263714 0.41721788531309045 0.528543473485797 0.7241178783415191 1.0 12.79362549054709 -4.759349959452151 4.522177930623224 0.5951990931574884 1.2831431371351933 0.5800974234778118 0.15254456377336906 0.13158433522115195 5.9602951524163315 0.035396116540070154 0.29646239161440563 1.74040387087929e-05 4.759349959452151 0.6879440439777049 NADDDRGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NADDDRGPR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 ; 101.25 0.004612 6456100.0 11726.0 21174.0 15095.9 10976.6 38366.0 36242.0 13875.3 27074.0 33905.0 39942.0 False True 13710.980200943142 23276.014785908992 15455.843507519565 10361.616688617352 30848.457712635445 34341.40571960531 12560.931135527255 26363.336187274206 34400.796483041806 47183.16841930196 0.2905904936077624 0.49331182211127445 0.3275711238840162 0.21960408840154455 0.653802166028676 0.7278317007968615 0.26621635545756944 0.5587445072147664 0.7290904285471624 1.0 15.525984680478121 -14.522878745280336 0.1057602794587346 2.813439277348961 0.12793567376578527 0.5856375449053597 0.15519750591695394 133.8519533775858 0.9471226634766461 52.07230148509094 2.3203829685783264 3.0000000000000132e-15 14.522878745280336 -2.6855036035831756 NADDDRGPR ddPTM_PC-9_Lapatinib_30min_R1 1 NADDDRGPR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 101.25 0.004612 4721200.0 6207.6 13882.0 6241.7 10806.0 11551.0 5711.8 17035.0 13902.0 12252.0 9730.6 False True 6119.07848566558 13849.857081907534 5728.531519658759 11600.709287759273 10871.592890139766 5467.519628856124 17916.98894710484 14547.937671746145 10872.05074072032 11412.521244790512 0.5361723631803764 1.213566817080809 0.501951444101247 1.0164896116232567 0.9526022039260024 0.4790807843053864 1.5699413444933066 1.2747347724226021 0.952642322193538 1.0 13.478329925386582 -7.2598913697820215 24.997477710306306 1.2222241635972597 0.8083727243487131 0.35303941566275465 0.27394159365845705 156.85291590499264 2532910.694518165 0.10455543219255413 0.0765612003142861 5.4967834788506114e-08 7.2598913697820215 -0.4138514392485466 NADHSMNYQYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NADHSMNYQYR 11 0 Q12906-7;Q12906;K7ELV3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 0 64.64 0.031675999999999996 3946800.0 4352.8 4214.1 4947.5 5037.6 4830.7 5304.5 5641.9 4687.3 6428.9 4797.7 False True 5089.643068281196 4632.447997983333 5065.467163498238 4755.3596041195615 3884.159012470104 5026.322681961439 5107.458388181244 4564.263341604872 6522.910500216116 5667.485031427693 0.8980426132681054 0.8173727803946887 0.8937768931737609 0.8390599318304052 0.6853408506474075 0.886870040959819 0.9011860392853349 0.805341931437813 1.1509356379496134 1.0 12.4684929602861 -8.255373489248377 24.991087431332282 1.075467826804129 0.8401526546886775 0.6414207735291777 0.07015966778927146 269.24175089679505 1109270.8901642289 0.049943890398470234 0.017791940641482387 5.554263902470425e-09 8.255373489248377 -0.2353151721154514 NADHSMNYQYR ddPTM_PC-9_Lapatinib_30min_R1 2 NADHSMNYQYR 11 0 Q12906-7;Q12906;K7ELV3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 0 ; 74.611 0.015365 5849900.0 8349.2 11372.2 10306.7 8726.7 7195.6 11524.8 6429.9 9133.8 9876.5 6202.5 False True 8230.138876944242 11345.868369605889 9459.322911012534 9368.490629417809 6772.368955093906 11031.911169620971 6762.808760257673 9558.189692576247 8764.104565844293 7274.593860688255 1.1313537270334406 1.559656605837298 1.3003231647240827 1.2878369306697555 0.9309617945397116 1.5164985676021279 0.9296476050441446 1.3139138590579598 1.2047551703477661 1.0 12.828650989517786 -1.819450590251828 0.02779228658374807 4.315753003157395e-06 2.9245527392748567 0.14731974445456564 0.1953233396085709 2765.877137808326 6.216938608919111 219.95253512719313 480.46559488617436 0.015154772099600493 1.819450590251828 2.9245484235218537 NADSELMPPPPERGDPPRLS(ph)PDPVAGSAVSQELR ddPTM_PC-9_AZD4547_30min_R2 1 NADSELMPPPPERGDPPRLSPDPVAGSAVSQELR 34 2 E9PMR3;E9PMG4;Q9BUR4 E9PMR3 WRAP53 Telomerase Cajal body protein 1 1 NADS(0.001)ELMPPPPERGDPPRLS(0.932)PDPVAGS(0.063)AVS(0.004)QELR 49.623000000000005 0.01798 16985000.0 39355.0 23364.0 46649.0 80230.0 54749.0 47969.0 33935.0 45757.0 37235.0 50699.0 True False 51869.071365147596 30915.95609207805 46030.40378008488 61734.21304114354 47148.04638653044 44969.49084691767 36955.14925919414 38686.307041257285 39203.1660832409 48924.0434415746 1.0601959224218653 0.6319174360352713 0.940854445832031 1.261837916460583 0.9636988905635925 0.9191695469860443 0.7553576249952891 0.790742226518066 0.801306746652238 1.0 15.578256023235712 -7.0595465335879375 4.819791188626659 0.8199112486646366 0.9654753444634189 0.13655028120502577 0.15703165474387543 0.4469231958297453 21.24883295996279 0.0642848549762606 0.0504243368291358 8.718734771786592e-08 7.0595465335879375 0.14556409579878227 NADSELMPPPPERGDPPRLS(ph)PDPVAGSAVSQELR ddPTM_PC-9_Lapatinib_30min_R1 1 NADSELMPPPPERGDPPRLSPDPVAGSAVSQELR 34 2 E9PMR3;E9PMG4;Q9BUR4 E9PMR3 WRAP53 Telomerase Cajal body protein 1 1 NADS(0.023)ELMPPPPERGDPPRLS(0.887)PDPVAGS(0.045)AVS(0.045)QELR 46.785 0.0033764000000000003 6788100.0 29424.0 17301.0 19027.0 16519.0 18386.0 16900.0 16974.0 17362.0 21473.0 13331.0 True False 29004.40836429925 17260.940597470268 17462.673506343974 17733.862365768597 17304.57162826678 16177.22639582416 17852.830665580128 18168.70190309715 19054.48461928562 15635.24558755907 1.8550657360558502 1.1039763015430188 1.1168787473500885 1.1342234611191135 1.1067668576972012 1.0346640419064697 1.1418324429637092 1.1620349550220015 1.2186879005243916 1.0 13.932514259840286 -4.760811817807243 24.999985060426624 1.1172997865327219 1.855066580524631 0.9356641304824933 0.058348615132504056 3.4160426752695554 135977.5748334284 0.014429258536473416 0.08353213156189926 1.734555427370303e-05 4.760811817807243 0.737766793991909 NADSRGS(ph)LISTDSGNSLPER ddPTM_PC-9_AZD4547_30min_R2 2 NADSRGSLISTDSGNSLPER 20 1 Q6ZSL5;A0A088AWN3;A0A0A0MSY4;Q9BZ29-3;Q9BZ29-5;Q9BZ29;Q9BZ29-4;A0A1B0GVL8 Q6ZSL5 DOCK9 Dedicator of cytokinesis protein 9 1 NADS(0.185)RGS(0.782)LIS(0.026)T(0.007)DSGNSLPER;NADS(0.086)RGS(0.609)LIS(0.231)T(0.065)DS(0.008)GNS(0.001)LPER 91.37799999999999 0.00030849 10234500.0 27844.0 22117.7 21663.7 44250.0 43735.0 36279.0 30737.0 34188.0 31671.0 39049.0 True False 36697.812808821494 29266.813989802882 21376.425183189887 34048.84615568494 37663.15017105167 34010.46839490765 33472.53345454104 28905.030162084586 33345.06440237204 37681.90639559058 0.9738841879060492 0.776680820830965 0.56728619191335 0.9035860818249162 0.9995022485236812 0.9025676152862439 0.8882919325562013 0.7670798249598901 0.8849091670763763 1.0 15.201584334890029 NADSRGS(ph)LISTDSGNSLPER ddPTM_PC-9_Lapatinib_30min_R1 1 NADSRGSLISTDSGNSLPER 20 1 Q6ZSL5;A0A088AWN3;A0A0A0MSY4;Q9BZ29-3;Q9BZ29-5;Q9BZ29;Q9BZ29-4;A0A1B0GVL8 Q6ZSL5 DOCK9 Dedicator of cytokinesis protein 9 1 NADS(0.173)RGS(0.755)LIS(0.052)T(0.013)DS(0.006)GNS(0.002)LPER 68.08800000000001 0.0024757 5194500.0 31503.0 25708.0 24676.0 26633.0 21070.0 18190.0 12122.0 20507.0 29743.0 19526.0 True False 31053.76144305736 25648.47470549481 22647.23453211458 28591.679665083535 19830.704025213825 17412.05610296104 12749.617846598467 21459.830084484114 26393.030132324893 22901.043083240453 1.3559976866635943 1.119969715452175 0.9889171619736563 1.2484880955491338 0.8659301654135755 0.7603171628327974 0.5567265124237486 0.9370678010814689 1.1524815719699668 1.0 14.483125690393358 -6.274379504965265 22.73152335850719 0.8535839767225304 1.1606431878666361 0.41894858852904393 0.1708059530198698 236.64996012496582 415714.3064024305 0.056062797523741645 0.06407349087557145 5.316434835681057e-07 6.274379504965265 0.3070592111441057 NAEAVLQS(ph)PGLSGK ddPTM_PC-9_AZD4547_30min_R2 5 NAEAVLQSPGLSGK 14 0 Q13045-2;Q13045-3;Q13045 Q13045-2 FLII Protein flightless-1 homolog 1 NAEAVLQS(0.997)PGLS(0.003)GK;NAEAVLQS(1)PGLSGK;NAEAVLQS(1)PGLSGK;NAEAVLQS(0.971)PGLS(0.029)GK;NAEAVLQS(0.996)PGLS(0.004)GK 165.16 7.8125e-05 1004400000.0 447913.0 424468.0 493771.0 736645.0 576999.0 538120.0 503000.0 566142.0 437110.0 522880.0 True False 590340.01683083 561668.9800758514 487223.27391576 566822.8763017978 496892.6485777214 504471.27133238845 547766.0255598834 478657.7625489321 460214.74222224904 504574.1303522864 1.169976781050315 1.113154532285875 0.9656128695610845 1.1233688812108742 0.9847763067654659 0.9997961468618572 1.0856006929595083 0.9486371451797185 0.9120854886098376 1.0 18.944706715294814 -1.5228787452803378 0.3613041552663815 0.9769195299979802 3.362797657807554 0.4939462313580604 0.05816041069281215 57.117836133316494 0.7962671272111344 0.04822914503190617 93.83178791632353 0.02999999999999998 1.5228787452803378 2.3858781278095735 NAEAVLQS(ph)PGLSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 NAEAVLQSPGLSGK 14 0 Q13045-2;Q13045-3;Q13045 Q13045-2 FLII Protein flightless-1 homolog 1 NAEAVLQS(0.995)PGLS(0.005)GK;NAEAVLQS(0.996)PGLS(0.004)GK;NAEAVLQS(0.996)PGLS(0.004)GK;NAEAVLQS(1)PGLSGK;NAEAVLQS(1)PGLSGK;NAEAVLQS(0.999)PGLS(0.001)GK;NAEAVLQS(1)PGLSGK 184.92 6.220599999999999e-06 867359000.0 929935.0 947610.0 825360.0 1103126.0 1120706.0 933879.0 1118343.0 1020987.0 952756.0 771805.0 True False 1087354.6284465338 1041682.458263685 845039.7125952314 1041321.4266027439 901111.7043553336 884904.7412399795 1012405.4549378369 994187.1730751479 966688.2540627354 911727.1368949797 1.192631637739422 1.1425375160064744 0.9268559401150851 1.142141529481196 0.9883567877821444 0.9705806764221718 1.110425931146167 1.0904437663893585 1.0602824188769173 1.0 19.79824259142562 -5.019529963733528 22.0447017767885 1.041286739547098 1.1801083569231916 0.4133967954112103 0.06362855336243306 135.20860707223244 152624.5004434412 0.015895535603099666 0.043821371565960075 9.560267325918214e-06 5.019529963733528 0.13882161737609366 NAEAVLQS(ph)PGLSGK ddPTM_PC-9_Lapatinib_30min_R1 4 NAEAVLQSPGLSGK 14 0 Q13045-2;Q13045-3;Q13045 Q13045-2 FLII Protein flightless-1 homolog 1 NAEAVLQS(1)PGLSGK;NAEAVLQS(1)PGLSGK;NAEAVLQS(1)PGLSGK;NAEAVLQS(0.941)PGLS(0.059)GK 171.87 3.4483e-05 1041590000.0 1017650.0 768040.0 826530.0 722020.0 798730.0 774070.0 725490.0 690100.0 756970.0 566610.0 True False 1003138.1243858455 766261.650568236 758575.8938980636 775119.7593881129 751750.2717635995 740964.8305453019 763052.3223501663 722164.5653339085 671712.0673525196 664547.7835396321 1.5095048832196136 1.153057266231237 1.1414918726500032 1.1663867950315518 1.1312207946274293 1.1149910494000053 1.1482279246886684 1.0867007357806353 1.0107806902533447 1.0 19.342013412985942 -2.3517079730725805 1.2382131666156249 1.1027971514227195 199.98151430349736 0.8377262188735045 0.05358161920537997 282.0193248477983 1.1840909385078815 0.015971222813038716 158464.21314238786 0.0044493034556662295 2.3517079730725805 198.87871715207464 NAEEES(ph)ESEAEEGD ddPTM_PC-9_AZD4547_30min_R2 1 NAEEESESEAEEGD 14 0 H0Y503;Q7L1Q6-2;Q7L1Q6;Q7L1Q6-4;Q7L1Q6-3 H0Y503 BZW1 Basic leucine zipper and W2 domain-containing protein 1 1 NAEEES(0.573)ES(0.427)EAEEGD 110.25 0.0026871 0.0 2553.3 1908.6 3743.5 5510.6 3880.4 2670.5 4331.7 3651.1 2160.9 2876.3 True False 3365.1962880607643 2525.517625292763 3693.858744040554 4240.216307921299 3341.673440579604 2503.5132128394084 4717.212908385182 3086.906388931409 2275.120762435217 2775.601612477583 1.212420497571657 0.9098991778717165 1.3308317474074776 1.527674680998747 1.2039456331042873 0.9019713785959 1.6995280904792602 1.1121575859641997 0.8196856321914217 1.0 11.438584794599663 -8.004782810481734 24.990740562032528 0.928535656125437 1.2516007671049114 0.2579083000680803 0.23300118284353194 279.3516332466838 1459636.1727032824 0.13487169459289358 0.0620200789492317 9.890475910749257e-09 8.004782810481734 0.32306511097947443 NAEEES(ph)ESEAEEGD ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NAEEESESEAEEGD 14 0 H0Y503;Q7L1Q6-2;Q7L1Q6;Q7L1Q6-4;Q7L1Q6-3 H0Y503 BZW1 Basic leucine zipper and W2 domain-containing protein 1 1 NAEEES(0.922)ES(0.078)EAEEGD;NAEEES(0.997)ES(0.003)EAEEGD 172.58 0.00017511 5535400.0 11163.8 10992.4 13126.4 18139.0 16548.8 17264.3 17956.7 17883.699999999997 15108.599999999999 10581.8 True False 13053.61084489929 12083.652825759242 13439.383158149223 17122.73063743145 13306.181436554798 16358.929715936827 16255.711380750145 17414.271824346437 15329.534692336989 12500.19657451729 1.0442724454037933 0.9666770241351879 1.0751337451401801 1.3697969096212126 1.0644777749880012 1.3086937968068353 1.3004364598464628 1.3931198377989435 1.2263434899565935 1.0 13.60966316202492 -5.593733173540244 6.148400275152348 1.251717880998144 1.0088662677097455 0.3965877941451431 0.11909783414575997 0.17487676803726385 11.47497572553481 0.031304588587823846 0.055003536000719604 2.548395482006902e-06 5.593733173540244 -0.24285161328839844 NAEEES(ph)ESEAEEGD ddPTM_PC-9_Lapatinib_30min_R1 2 NAEEESESEAEEGD 14 0 H0Y503;Q7L1Q6-2;Q7L1Q6;Q7L1Q6-4;Q7L1Q6-3 H0Y503 BZW1 Basic leucine zipper and W2 domain-containing protein 1 1 NAEEES(0.994)ES(0.006)EAEEGD;NAEEES(0.981)ES(0.019)EAEEGD 134.88 7.498800000000001e-05 0.0 7128.2 6660.5 8195.8 6772.700000000001 6726.5 6758.5 6261.3 8203.2 7436.6 7228.200000000001 True False 7026.550560848214 6645.078021469899 7521.972960702894 7270.786951064889 6330.860494807818 6469.454709832994 6585.479477223805 8584.35061925392 6599.011797130325 8477.58473902892 0.8288387290898472 0.7838409436212926 0.8872778264395752 0.8576483957266505 0.7467764333468636 0.7631247470814487 0.7768108110917155 1.0125939030409774 0.7784070581742389 1.0 13.049437584669596 -8.91176057244592 0.6413993053366115 0.9996028946883884 0.8125680147221633 0.3217872203736042 0.07524259533288227 1.696877841097346 1.3081139421910997 0.0870754670507194 0.030792515317433048 1.2252915191485941e-09 8.91176057244592 -0.18703487996622503 NAEQYKDQADK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NAEQYKDQADK 11 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 78.488 0.023767 5581600.0 12355.0 16424.0 16814.0 20719.0 18939.0 17795.0 13951.0 16884.0 18784.0 11946.0 False True 14446.457477626855 18054.466177565395 17214.909527450098 19558.181601904304 15228.03890474907 16861.798873692856 12629.460283506729 16440.81289007674 19058.68046416332 14111.715235516025 1.0237208756358942 1.2793955856001367 1.2199019920784702 1.3859535340311249 1.0791061646725628 1.1948794737053288 0.89496280733622 1.1650470985057082 1.3505573309895662 1.0 13.784605733280456 NAEQYKDQADK ddPTM_PC-9_Lapatinib_30min_R1 1 NAEQYKDQADK 11 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 88.155 0.012938999999999999 21330000.0 63157.0 71186.0 78666.0 43392.0 62169.0 66777.0 53036.0 45495.0 70939.0 48203.0 False True 62256.36959842465 71021.17319065482 72198.38513954148 46583.19243146865 58512.341648956724 63921.1033747899 55781.944572858956 47608.86378766299 62949.10279921305 56534.82432353981 1.1012039100385516 1.2562376206249788 1.2770603960200106 0.8239734179570533 1.0349787471541416 1.1306500752346835 0.9866829028003652 0.8421157111094045 1.1134571222679555 1.0 15.786852192245517 -5.743603306764327 24.99811381986986 0.9912500322295642 1.2159743930069644 0.49421078913782046 0.10253003513334254 204.90680227241515 287184.54275778297 0.02804507224327501 0.04844345891668227 1.8046654055902738e-06 5.743603306764327 0.2247243607774002 NAGVEGSLIVEK ddPTM_PC-9_Lapatinib_30min_R1 2 NAGVEGSLIVEK 12 0 P10809 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 ; 125.82 0.0012984000000000001 7832100.0 31281.0 28774.0 33390.0 26104.7 26892.0 24972.0 32942.0 24884.0 28546.0 25632.0 False True 30834.927203767144 28707.375570869273 30644.80308912732 28024.52672072638 25310.265431706222 23904.00577257521 34647.57557355609 26040.201483508223 25330.848877293676 30062.457047506876 1.0256955096863691 0.9549244602829302 1.0193712057766995 0.9322101209638317 0.8419227141583638 0.7951447792441039 1.1525197530861657 0.8662033659576663 0.8426074035553391 1.0 14.875675307146704 -5.881318842402506 5.64876627587197 0.9131313440534821 0.9949133575070408 0.12858009362719036 0.09707103033464057 0.4609129597808653 20.944452008671075 0.02818520067933664 0.04244225175299745 1.3142595987727505e-06 5.881318842402506 0.08178201345355873 NAIS(ph)LPQLNQAAYDSLVVGK ddPTM_PC-9_AZD4547_30min_R2 2 NAISLPQLNQAAYDSLVVGK 20 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 NAIS(1)LPQLNQAAYDSLVVGK;NAIS(1)LPQLNQAAYDSLVVGK 144.23 5.5113e-06 24542000.0 228733.0 224813.0 354300.0 540100.0 495250.0 488580.0 421030.0 452120.0 418380.0 463940.0 True False 301465.3360580432 297479.40579217375 349601.75050449255 415588.2894618177 426493.08613726636 458029.01536381955 458500.85435681377 382255.24268403143 440494.7126603019 447697.6018123446 0.6733682173808122 0.6644650420014182 0.7808881465731649 0.9282790164152236 0.9526365216404123 1.023076767687948 1.0241306911199346 0.8538246377389714 0.9839112625958137 1.0 18.77216506459539 -5.632577283386296 1.9194097357589082 0.970873419241348 0.6628844682332403 0.8791329512806659 0.04572666423688273 0.11337925765938657 0.8375654431645801 0.01449705422615049 0.033652179401747 2.3303583874417807e-06 5.632577283386296 -0.30798895100810764 NAIS(ph)LPQLNQAAYDSLVVGK ddPTM_PC-9_Lapatinib_30min_R1 2 NAISLPQLNQAAYDSLVVGK 20 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 NAIS(1)LPQLNQAAYDSLVVGK;NAIS(1)LPQLNQAAYDSLVVGK 127.94 8.7695e-06 36856000.0 522710.0 454670.0 446540.0 424880.0 452610.0 471290.0 386920.0 356610.0 469700.0 359830.0 True False 515256.05954672676 453617.2395498415 409827.2048942479 456127.0925581315 425988.36966549745 451134.02533064876 406952.8243858997 373179.4024688108 416797.43983972736 422026.13605666306 1.2209103075017758 1.0748557987151224 0.9710943704188565 1.080802949362572 1.0093885976964763 1.0689717692509868 0.9642834640252244 0.8842566149000453 0.9876104919335288 1.0 18.686972822164854 -1.5228787452803376 0.629034791217074 0.9817071298395618 18.474539085296147 0.63406744914054 0.05223641112167714 138.6499552542441 0.9679593035021337 0.024497316612808843 3360.4077746644493 0.029999999999999995 1.5228787452803376 17.492831955456584 NAIS(ph)LPVIGGPQALTLPTAQAPPKPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NAISLPVIGGPQALTLPTAQAPPKPPR 27 1 O14613 O14613 CDC42EP2 Cdc42 effector protein 2 1 NAIS(1)LPVIGGPQALTLPTAQAPPKPPR 92.266 7.7893e-08 9169300.0 18121.0 19911.0 34550.0 35075.0 46900.0 44982.0 44803.0 40511.0 44218.0 36716.0 True False 21188.52739393575 21887.63249278521 35373.80303160468 33109.86146468428 37710.28167446702 42623.06473371467 40558.935494369725 39447.62917495251 44864.604597762656 43372.320156303926 0.48852649149450944 0.5046451841614004 0.8155847532279938 0.7633869100238104 0.8694550242774144 0.9827250324656577 0.9351340981576405 0.9095116201483405 1.0344063779867179 1.0 15.404487000257097 -4.876488538288075 0.541657301186545 0.9860158991230148 0.11084888753805937 0.9108959659438303 0.055044691967593956 0.9968281955672558 0.24039392999963752 0.03164566091099568 0.5462811812739699 1.328958629964589e-05 4.876488538288075 -0.8751670115849555 down NALESYAFNMK ddPTM_PC-9_Lapatinib_30min_R1 1 NALESYAFNMK 11 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 147.91 0.0012394 5034300.0 28244.0 29837.0 27449.0 25185.0 33205.0 30543.0 31678.0 23166.0 30025.0 23532.0 False True 27841.235380684753 29767.914259679816 25192.249176204106 27037.18891469714 31251.947183541753 29236.74708921048 33318.13183835559 24242.376931640854 26643.268322733227 27599.474845580986 1.0087596063496287 1.078568140380614 0.9127800190820549 0.9796269336996507 1.1323384723222578 1.059322586853193 1.2072016596247024 0.8783637031964163 0.965354176911056 1.0 14.752353195651299 -7.807447252733423 24.99999708401562 0.9413942892421491 1.0499405921523923 0.26237780490335094 0.08115583301994289 185.1803153823119 100621.83778029004 0.046052293754811055 0.022122918906435148 1.5579472439322924e-08 7.807447252733423 0.10854630291024325 NALFPEVFS(ph)PTPDENSDQNSR ddPTM_PC-9_AZD4547_30min_R2 6 NALFPEVFSPTPDENSDQNSR 21 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 NALFPEVFS(0.999)PT(0.001)PDENSDQNSR;NALFPEVFS(0.978)PT(0.022)PDENSDQNSR;NALFPEVFS(0.995)PT(0.005)PDENSDQNSR;NALFPEVFS(0.989)PT(0.011)PDENSDQNSR;NALFPEVFS(0.991)PT(0.009)PDENSDQNSR;NALFPEVFS(0.988)PT(0.012)PDENSDQNSR 106.51 0.00010287 11376300.0 63565.899999999994 60816.200000000004 76132.9 106621.0 82585.3 81700.9 72682.79999999999 97169.5 76148.5 91772.8 True False 83778.53394714357 80473.84732438967 75123.32800164686 82041.17572802906 71119.75662104401 76592.12980747833 79151.42839475922 82154.18650797592 80173.55424975617 88559.86220546637 0.9460102111808879 0.9086943601795985 0.8482773813192526 0.9263923145870145 0.8030698653983919 0.8648627933699592 0.8937618738737557 0.9276684093903765 0.905303511694121 1.0 16.43436535691231 -8.813530440936558 0.9070840694410689 0.9992084372783948 0.8827488480601889 0.41603628245561286 0.03968503523865843 1.0317777765506 1.5990952499422193 0.03960078227642412 0.013245820550722485 1.5362771075217976e-09 8.813530440936558 -0.11645958921820587 NALFPEVFS(ph)PTPDENSDQNSR ddPTM_PC-9_Lapatinib_30min_R1 2 NALFPEVFSPTPDENSDQNSR 21 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 NALFPEVFS(0.969)PT(0.03)PDENSDQNSR;NALFPEVFS(0.993)PT(0.007)PDENSDQNSR 83.09 0.00056573 1518100.0 15133.0 13275.9 16922.4 13933.2 17555.6 15060.099999999999 15098.099999999999 15904.3 17924.9 15537.0 True False 14917.20064494768 13245.160469218863 15531.105594353045 14957.89400779265 16523.01412363757 14416.01462980778 15879.805742429338 16643.271839501675 15906.009004435009 18222.54974824884 0.8186121509357493 0.7268554978422657 0.8523014511646791 0.8208452831487033 0.9067344774419074 0.7911085346985066 0.8714370909567891 0.9133338676219593 0.8728750490015018 1.0 14.153437218589998 -14.52287873105026 0.027885624186569084 2.073231766043791 0.10473276839512646 0.6475099419174147 0.04224809358300789 995.3641445356529 2.084684619145372 111.43077477072326 47.97788358018112 3.00000009829789e-15 14.52287873105026 -1.9684989976486644 NALLHK ddPTM_PC-9_Lapatinib_30min_R1 1 NALLHK 6 0 A0A1B0GVP4;A8MVM7 A0A1B0GVP4 Putative uncharacterized protein ENSP00000382790 0 76.592 0.028489999999999998 0.0 47095.0 37668.0 42251.0 33839.0 42660.0 35171.0 37063.0 39784.0 42074.0 33036.0 False True 46423.416663834745 37580.782060315025 38777.28587357646 36327.63294359486 40150.82267278698 33666.81831760542 38981.94078934821 41632.50987863251 37335.18306113832 38746.22858229698 1.1981402671290038 0.9699210332302008 1.0008015564976476 0.9375785533922347 1.0362511176412084 0.8689056857778328 1.006083487752894 1.074491928684235 0.9635823776200153 1.0 15.24176827005471 -4.759102565325634 24.99474797462615 0.9842799759652128 1.198140545663443 0.5957140896002222 0.05287863108616302 43.61422934227129 466398.26987209485 0.013044996048557673 0.0849044517908722 1.741395567462319e-05 4.759102565325634 0.2138605696982303 NALLS(ph)LAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NALLSLAK 8 0 P04083;Q5T3N1 P04083;Q5T3N1 ANXA1 Annexin A1;Annexin 1 NALLS(1)LAK 75.566 0.026189999999999998 2957400.0 31992.0 38095.0 23716.0 35805.0 39284.0 33938.0 39117.0 31758.0 29052.0 32624.0 True False 37407.613729197765 41876.819838915835 24281.479383430844 33798.9619313762 31586.58220255356 32158.231535565526 35411.55457744479 30924.386150382437 29476.830539015813 38538.47294855809 0.9706563562892121 1.0866237459593646 0.6300581607331002 0.8770187126119844 0.8196116707767832 0.8344448826109682 0.9188624215783752 0.8024289439714156 0.7648676318431731 1.0 15.234011786855394 -5.231251744565027 24.991670607289862 0.82836581921803 1.028640092085119 0.40748531152090073 0.09533286440112793 631.0570790512157 522436.16626673494 0.022842195316325458 0.060418550702924435 5.871489052050935e-06 5.231251744565027 0.2002742728670891 NALLSLAK ddPTM_PC-9_Lapatinib_30min_R1 1 NALLSLAK 8 0 P04083;Q5T3N1 P04083;Q5T3N1 ANXA1 Annexin A1;Annexin 0 120.15 0.015795 18224000.0 74630.0 72307.0 76885.0 73545.0 87547.0 53966.0 76392.0 69050.0 57688.0 71436.0 False True 73565.76251453401 72139.57758402878 70563.81208468274 78953.74463892807 82397.65758402449 51657.999980890345 80347.20397107332 72258.3150794181 51190.569958429136 83783.61741751341 0.8780447154476343 0.8610224744121557 0.8422149133648255 0.9423530168849483 0.9834578659144979 0.6165644498669283 0.9589846612934408 0.8624396666873188 0.6109854352949996 1.0 16.354380554487264 NALPPVLTTVNGQS(ph)PPEHSAPAK ddPTM_PC-9_AZD4547_30min_R2 3 NALPPVLTTVNGQSPPEHSAPAK 23 0 Q6PKG0;A0A0B4J210;H0YBM7 Q6PKG0 LARP1 La-related protein 1 1 NALPPVLT(0.001)T(0.001)VNGQS(0.999)PPEHSAPAK;NALPPVLTTVNGQS(1)PPEHSAPAK;NALPPVLT(0.007)T(0.007)VNGQS(0.987)PPEHSAPAK 121.48 6.7647e-09 990590000.0 2005162.0 1865767.0 2143943.0 3119455.0 2675214.0 2421975.0 2147050.0 2421523.0 2069183.0 2475418.0 True False 2642761.8060394325 2468839.695687731 2115512.914992529 2400312.8448493127 2303806.713654968 2270528.5203769817 2338133.2906130184 2047332.2614128224 2178555.7890591808 2388754.3692785944 1.1063346822208215 1.0335259779904964 0.8856134151756321 1.0048387041042688 0.9644385137642759 0.9505073228030068 0.9788085877239594 0.8570710692330908 0.9120049416035632 1.0 21.187827081367637 -5.023543224278212 4.175197701197008 0.9435590679854367 1.0961961157039009 0.5707576848277376 0.04560711248187289 0.13839098672883815 5.5848131939599135 0.011955262615621597 0.043531743075381955 9.47232904015203e-06 5.023543224278212 0.1526370477184642 NALPPVLTTVNGQS(ph)PPEHSAPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 NALPPVLTTVNGQSPPEHSAPAK 23 0 Q6PKG0;A0A0B4J210;H0YBM7 Q6PKG0 LARP1 La-related protein 1 1 NALPPVLTTVNGQS(0.999)PPEHS(0.001)APAK;NALPPVLT(0.008)T(0.017)VNGQS(0.945)PPEHS(0.03)APAK;NALPPVLTTVNGQS(1)PPEHSAPAK;NALPPVLT(0.011)T(0.013)VNGQS(0.976)PPEHSAPAK;NALPPVLT(0.193)T(0.193)VNGQS(0.614)PPEHSAPAK;NALPPVLT(0.007)T(0.019)VNGQS(0.974)PPEHSAPAK 100.79 2.9956e-06 846814300.0 2206884.0 2130303.0 1937239.0 2659490.0 2894272.0 2420196.0 2565144.0 2637511.0 2483951.0 1989336.0 True False 2580465.873254158 2341785.403157941 1983430.1247798165 2510487.397482916 2327160.1783054005 2293276.6612484404 2322154.990285688 2568279.130923898 2520274.084201386 2349986.8692248906 1.0980767199372854 0.9965099949389697 0.844017535057131 1.0682984787531873 0.9902864602273207 0.975867861765902 0.9881565810840541 1.092890843160757 1.0724630495627674 1.0 21.164221264941233 -7.746737307099331 24.838692222331133 1.0620077055973838 0.990716186754453 0.1447470418192106 0.066509103855695 355.4093316124377 600455.3030938142 0.031669650259901407 0.01817935175821279 1.7916892703666102e-08 7.746737307099331 -0.07129151884293072 NALPPVLTTVNGQS(ph)PPEHSAPAK ddPTM_PC-9_Lapatinib_30min_R1 2 NALPPVLTTVNGQSPPEHSAPAK 23 0 Q6PKG0;A0A0B4J210;H0YBM7 Q6PKG0 LARP1 La-related protein 1 1 NALPPVLT(0.001)TVNGQS(0.997)PPEHS(0.002)APAK;NALPPVLTTVNGQS(1)PPEHSAPAK 123.68 7.037100000000001e-09 780560000.0 4151900.0 3516200.0 3341100.0 3125000.0 3527300.0 3304400.0 2884860.0 3037300.0 3443700.0 2752100.0 True False 4092693.1446347814 3508058.4549346776 3066407.6550189685 3354822.924694395 3319831.1489386205 3163078.5149326213 3034223.935071607 3178424.0462087896 3055834.2422313527 3227796.818057263 1.2679525308839235 1.0868275336630693 0.9500002100084383 1.0393538112208645 1.0285130496338835 0.9799496973407409 0.9400294089445931 0.9847038786418442 0.9467244732184195 1.0 21.6221183366614 -4.834488538770105 2.405395311176582 0.9849283695025001 1.315819147565439 0.8798815122283761 0.032187288908765176 0.159969242776807 1.2647450402438096 0.008972415248685627 0.10689564872399726 1.4639001700354912e-05 4.834488538770105 0.330890778062939 NALQQENHIIDGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NALQQENHIIDGVK 14 0 H0YJW7;A0A087WUN7;H0YJ40;G3V4X6;G3V2S9;Q9GZT3-2;Q9GZT3 H0YJW7 SLIRP SRA stem-loop-interacting RNA-binding protein, mitochondrial 0 70.889 0.022124 3307400.0 23537.0 23347.0 21882.0 26324.0 32593.0 28946.0 26362.0 18764.0 24983.0 20435.0 False True 27521.349223059773 25664.735865052306 22403.749867947135 24849.151623559494 26206.635620808196 27428.02080347928 23864.80051564793 18271.464882101387 25348.329111807514 24139.703736628995 1.1400864535590614 1.0631752628392561 0.9280871924684078 1.0293892540965197 1.0856237469494245 1.1362202743963536 0.9886119886150908 0.7569051004705047 1.0500679456701276 1.0 14.559120349746818 -7.523650610612457 24.99999752684059 0.9166436200504479 1.05745226859718 0.2843799802453866 0.09035971403521238 31.720613608342408 1027271.8636486104 0.041650349957219175 0.02430734131834442 2.9946728784878334e-08 7.523650610612457 0.14080864854673203 NALTTLAGPLT(ph)PPVK ddPTM_PC-9_AZD4547_30min_R2 2 NALTTLAGPLTPPVK 15 0 H0Y3X6;A0A0C4DFX9;Q9H3P2;C9JEM7;H7C2C7;C9JHL4;H7C0W2 H0Y3X6 NELFA Negative elongation factor A 1 NALT(0.001)T(0.064)LAGPLT(0.935)PPVK;NALTTLAGPLT(1)PPVK 159.81 0.00066621 22331400.0 73115.0 68470.0 87661.0 117811.0 94241.0 91803.0 74142.0 96188.0 77466.0 83866.0 True False 96364.04911352464 90601.58849617286 86498.55786332017 90651.49411180567 81157.26386807083 86062.54389750841 80740.49436791425 81324.35478034962 81560.69461002648 80929.87686682367 1.1907104377793516 1.1195073068659764 1.0688087170286962 1.1201239594245234 1.002809679318076 1.0634211644623028 0.9976599186080429 1.0048743174807382 1.0077946213144604 1.0 16.304384779984964 -1.5228787452807278 0.29552295152554453 0.9911423314205667 2.6359040791908668 0.8244900098824947 0.026757319877036338 20.19244333621566 0.28729349308441343 0.026643098677320714 17.467053229956523 0.029999999999973048 1.5228787452807278 1.6447617477703 NALTTLAGPLT(ph)PPVK ddPTM_PC-9_Lapatinib_30min_R1 2 NALTTLAGPLTPPVK 15 0 H0Y3X6;A0A0C4DFX9;Q9H3P2;C9JEM7;H7C2C7;C9JHL4;H7C0W2 H0Y3X6 NELFA Negative elongation factor A 1 NALTTLAGPLT(1)PPVK;NALTT(0.008)LAGPLT(0.991)PPVK 142.94 0.00011309 14919800.0 78307.0 61984.0 63372.0 62147.0 71185.0 62686.0 60205.0 57296.0 64906.0 53893.0 True False 77190.3278202548 61840.47985628557 58161.79878299417 66717.49769631446 66998.03825509478 60005.065908203134 63322.120314672604 59958.181329331586 57595.6027895195 63208.33324209141 1.2212049244300047 0.9783596036211415 0.9201602984883539 1.0555174337659365 1.05995578143927 0.9493220724296022 1.0018001909992689 0.9485803256303 0.9112026822306033 1.0 15.947827152105418 -4.760974802346916 24.999997855930292 0.9815634619418714 1.221205195117818 0.6917585423412639 0.04818985936682598 6.740047027618994 362316.7860669611 0.012608950922484553 0.07223692818474814 1.7339045955302394e-05 4.760974802346916 0.23964173317594661 NAMS(ph)LPQLNEK ddPTM_PC-9_AZD4547_30min_R2 5 NAMSLPQLNEK 11 0 Q9H3Q1;J3KRZ9 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 NAMS(1)LPQLNEK;NAMS(1)LPQLNEK;NAMS(1)LPQLNEK;NAMS(1)LPQLNEK;NAMS(1)LPQLNEK 123.95 0.00047223 124851400.0 255181.0 293747.0 409041.0 549639.0 532810.0 563608.0 439558.0 518044.0 435078.0 493653.0 True False 336323.24990546843 388694.9732143316 403616.849077358 422928.22038789914 458838.5284700603 528365.5026631682 478677.8104633237 437992.20326684625 458075.3348506591 476370.3587262782 0.7060121263731259 0.8159512154652663 0.8472753219922228 0.8878138881661888 0.9631970588953214 1.1091485710318227 1.0048438188791076 0.9194363067382118 0.9615949574937106 1.0 18.861724121373072 -5.598330533073513 1.0611299055683783 0.9958741343895271 0.7261610841386879 0.7747641658862363 0.05109080749607977 0.3503997760591089 0.6962915644180171 0.020898131392877006 0.0788270928268498 2.521560931071957e-06 5.598330533073513 -0.26971305025083925 NAMS(ph)LPQLNEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NAMSLPQLNEK 11 0 Q9H3Q1;J3KRZ9 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 NAMS(1)LPQLNEK;NAMS(1)LPQLNEK;NAMS(1)LPQLNEK 134.4 5.3933e-05 130662700.0 461691.0 521210.0 541289.0 712799.0 820186.0 644340.0 691263.0 562233.0 554911.0 510846.0 True False 539846.1674870912 572952.2842431124 554195.3826099631 672863.1829555376 659476.4410544655 610549.676104257 625781.5643292741 547474.9794851044 563025.5235865274 603458.3359452881 0.8945873067466181 0.9494479570749662 0.918365609685121 1.115011829112494 1.092828455209634 1.0117511677883457 1.0369921617687454 0.9072291273058837 0.9329981707926454 1.0 19.202894642102976 -5.649572934427766 19.943859604770566 1.0143694243163697 0.923617859391748 0.3311494628130043 0.06053975097101366 3.082304439194755 535.1793746929401 0.018418869628413603 0.031902421563478216 2.240923678553054e-06 5.649572934427766 -0.09075156492462166 NAMS(ph)LPQLNEK ddPTM_PC-9_Lapatinib_30min_R1 6 NAMSLPQLNEK 11 0 Q9H3Q1;J3KRZ9 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 NAMS(1)LPQLNEK;NAMS(1)LPQLNEK;NAMS(1)LPQLNEK;NAMS(1)LPQLNEK;NAMS(1)LPQLNEK;NAMS(1)LPQLNEK 115.06 0.0012295 160795000.0 982585.0 996657.0 963601.0 912801.0 862832.0 838142.0 740891.0 776776.0 840054.0 644773.0 True False 968573.1577159774 994349.3019509232 884377.4453874286 979931.4305548726 812081.9181529804 802296.6204644302 779250.7107724951 812867.848720203 745438.2723592113 756221.1539439828 1.280806749010521 1.3148922068167637 1.1694693288796032 1.2958265256719612 1.0738682909327018 1.0609285607525605 1.0304534681533364 1.0749075776058181 0.9857411003004417 1.0 19.528448681158444 -6.347009307930682 4.14907147831241 1.0380123135239816 1.2622451950150748 0.8649087364600924 0.044188923930822355 0.08145386392621393 2.572426997332998 0.013908815138020565 0.01602819634660897 4.4977021517871e-07 6.347009307930682 0.22423288149109322 NAPAAVDEGSIS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 NAPAAVDEGSISPR 14 0 A0A494C0S2;A0A090HNM7;A0A1W2PS85;R4GMW8;P28715 A0A494C0S2 ERCC5-201;BIVM-ERCC5;ERCC5 DNA repair protein complementing XP-G cells 1 NAPAAVDEGS(0.001)IS(0.999)PR;NAPAAVDEGS(0.144)IS(0.856)PR;NAPAAVDEGS(0.168)IS(0.832)PR 137.27 2.8843e-05 81709800.0 41318.6 36978.5 59713.5 66150.1 59423.0 51740.0 55054.2 55605.0 40527.4 55536.0 True False 54457.055319730316 48931.07697101986 58921.65997389221 50900.21645385712 51173.14216564315 48504.68962078677 59953.91714588257 47012.52492578431 42669.59562567307 53591.70154384278 1.0161471599325802 0.9130345848599318 1.0994549207527784 0.9497779504578002 0.9548706365253017 0.905078365185058 1.1187164321855865 0.8772351608825834 0.7961978141478779 1.0 15.70972200209041 -7.903663105736402 23.99629725147961 0.8774038064515192 0.9889100150027317 0.2425027953074198 0.08179933514516438 13.101177917711965 3248.0788358122895 0.04258239907434333 0.020455942555891327 1.2483515196047852e-08 7.903663105736402 0.11150620855121252 NAPAAVDEGSIS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NAPAAVDEGSISPR 14 0 A0A494C0S2;A0A090HNM7;A0A1W2PS85;R4GMW8;P28715 A0A494C0S2 ERCC5-201;BIVM-ERCC5;ERCC5 DNA repair protein complementing XP-G cells 1 NAPAAVDEGS(0.026)IS(0.974)PR;NAPAAVDEGS(0.001)IS(0.999)PR;NAPAAVDEGSIS(1)PR;NAPAAVDEGSIS(1)PR 213.0 3.1198e-15 143907800.0 77829.1 83024.6 81166.3 93237.8 103598.0 96947.0 84793.0 82570.4 77603.2 74302.2 True False 91004.02943520602 91266.73359753398 83101.61241690684 88013.98834702605 83298.71558446543 91862.92865456028 76760.793191842 80403.01449057035 78737.99998916964 87772.6006841083 1.0368159166517985 1.0398089254071552 0.9467830709037294 1.0027501482357404 0.9490286824729703 1.0466014216118875 0.8745416290910925 0.9160377368780386 0.8970680984211234 1.0 16.421483034273265 -7.263912641657415 24.997800917796024 0.9149150110294901 1.000169787373101 0.4440439933089845 0.044420211071432035 200.55684761000606 2027055.0122464169 0.017508406075014034 0.01243470520570906 5.446121905768962e-08 7.263912641657415 0.0852547763436109 NAPAAVDEGSIS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 NAPAAVDEGSISPR 14 0 A0A494C0S2;A0A090HNM7;A0A1W2PS85;R4GMW8;P28715 A0A494C0S2 ERCC5-201;BIVM-ERCC5;ERCC5 DNA repair protein complementing XP-G cells 1 NAPAAVDEGSIS(1)PR;NAPAAVDEGS(0.006)IS(0.994)PR;NAPAAVDEGSIS(1)PR;NAPAAVDEGS(0.013)IS(0.987)PR 219.03 1.206e-15 165016400.0 75296.0 60504.7 70306.0 61650.3 67682.8 66929.0 60144.3 69061.7 70263.4 57532.1 True False 74222.26523240485 60364.60508454771 64525.71206900831 66184.26872137195 63701.830773504546 64066.60268911921 63258.277565679935 72270.55870413131 62349.59598559648 67476.4468282954 1.0999729345748637 0.8946026046415142 0.9562701520606781 0.9808499384946631 0.9440602427629899 0.9494661574600529 0.9374867904151908 1.0710486710723712 0.924020142083874 1.0 16.042096385804427 NAPLPSLQNGPNTPNKPS(ph)SPPPPQQFVVQHSLFGSPVAK ddPTM_PC-9_AZD4547_30min_R2 1 NAPLPSLQNGPNTPNKPSSPPPPQQFVVQHSLFGSPVAK 39 1 Q9ULH7-4;Q9ULH7;Q9ULH7-5 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2 1 NAPLPS(0.005)LQNGPNT(0.014)PNKPS(0.49)S(0.49)PPPPQQFVVQHS(0.001)LFGSPVAK 70.473 5.509100000000001e-07 27415000.0 38482.0 40913.0 53358.0 91797.0 71937.0 71058.0 50017.0 78415.0 56569.0 65493.0 True False 50718.47552467564 54137.32715267885 52650.43805650214 70634.61989951206 61949.78927300663 66614.73202693975 54468.41610423201 66297.76354743946 59559.12185209759 63200.11000451771 0.8025061273002555 0.8566017867501967 0.8330751014948954 1.1176344454853469 0.9802164785564186 1.054028735427485 0.861840526865198 1.0490134201143055 0.9423895282435449 1.0 15.94763944907262 -5.729426871185263 24.700344947536 0.9983528433325543 0.8333148224339244 0.5823496615228367 0.0659432106507375 120.70654180151375 93134.24616268818 0.01725661211384497 0.029885868310052986 1.864546114012277e-06 5.729426871185263 -0.16503802089862984 NAPLPSLQNGPNTPNKPS(ph)SPPPPQQFVVQHSLFGSPVAK ddPTM_PC-9_Lapatinib_30min_R1 1 NAPLPSLQNGPNTPNKPSSPPPPQQFVVQHSLFGSPVAK 39 1 Q9ULH7-4;Q9ULH7;Q9ULH7-5 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2 1 NAPLPS(0.012)LQNGPNT(0.037)PNKPS(0.472)S(0.472)PPPPQQFVVQHS(0.006)LFGSPVAK 57.50899999999999 5.5673e-05 5194000.0 19700.0 12074.0 16850.0 12778.0 15490.0 20947.0 16480.0 13807.0 19473.0 13907.0 True False 19419.074387462453 12046.043394824346 15464.658042880968 13717.736746158429 14578.908654511722 20051.14563984193 17333.253762740696 14448.523624931593 17279.74568021929 16310.806420087301 1.1905649473926203 0.738531442564927 0.9481234492388878 0.8410213690761837 0.8938189982168699 1.2293166336121968 1.062685272347676 0.8858252162895978 1.0594047427930178 1.0 13.993540491427582 NAPSLPS(ph)RT(ph)CY(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 NAPSLPSRTCYK 12 1 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 3 NAPSLPS(1)RT(1)CY(1)K 74.464 0.034571 1763800.0 4624.9 3566.6 7108.6 7386.5 7263.4 5915.8 5352.2 6141.1 4113.8 5551.8 True False 6095.521996103949 4719.433701335628 7014.3353193232715 5683.656545287388 6255.002285410241 5545.88409081272 5828.5354314147335 5192.13410343915 4331.247069510846 5357.433171836402 1.137769114535599 0.8809132190664204 1.3092716407919136 1.0608917298615905 1.1675371553475062 1.0351755986368603 1.0879343231110896 0.9691458459498448 0.8084556410857098 1.0 12.387326233621486 -7.868399353772288 3.294532725288185 0.8992362801034339 1.0968913338264836 0.3428550595922788 0.1106477877066002 0.2635365670759746 5.535105458134455 0.06716802859962938 0.028903604473664662 1.353943826064266e-08 7.868399353772288 0.1976550537230497 NAPWTLTPEFLAEHR ddPTM_PC-9_AZD4547_30min_R2 1 NAPWTLTPEFLAEHR 15 0 P49585;C9JEJ2;C9J050;H7C1T3;C9J2E1;H7BZN1 P49585 PCYT1A Choline-phosphate cytidylyltransferase A 0 87.429 0.0090022 0.0 6142.4 6199.6 6737.6 10259.0 10441.0 9462.7 7047.6 8829.0 5213.8 7062.9 False True 8095.555430143124 8203.49946021431 6648.255021730367 7893.946049969987 8991.447374778802 8870.995873108208 7674.822746989737 7464.680920236482 5489.390823816338 6815.630020779443 1.1877926773403857 1.203630395899358 0.9754424758182613 1.158212230696646 1.3192393582641286 1.3015665237200935 1.1260621136403817 1.0952297729598317 0.8054120906035572 1.0 12.734631307186818 -8.042608319460937 3.322377968266365 0.9048040053920995 1.18231154628812 0.5435109884981241 0.10033884052163886 0.20267345464376496 4.368954912373583 0.08051901989043503 0.02864614211377077 9.065498294616767e-09 8.042608319460937 0.2775075408960205 NAQGWS(ph)PLAEAISY(ph)GDRQMITALLRK ddPTM_PC-9_AZD4547_30min_R2 1 NAQGWSPLAEAISYGDRQMITALLRK 26 2 Q8N6S4 Q8N6S4 ANKRD13C Ankyrin repeat domain-containing protein 13C 2 NAQGWS(0.834)PLAEAIS(0.2)Y(0.958)GDRQMIT(0.008)ALLRK 45.784 0.037252 0.0 6337.1 3733.6 6408.5 24142.0 16555.0 11395.0 4754.1 4457.4 4839.8 12587.0 True False 8352.165980131538 4940.41318547263 6323.519102760483 18576.43489018185 14256.62401010085 10682.468848644477 5177.205690087958 3768.6112508621673 5095.62194735247 12146.33296118462 0.6876286041904255 0.4067411292988955 0.5206113748872364 1.5293862723461935 1.1737389429105864 0.8794809826786295 0.42623610818445984 0.31026740851788887 0.4195193696431897 1.0 13.568233202250028 -7.256729360882627 23.42390094972243 0.48152799552558506 0.8737836524676301 0.16839929648058483 0.34675340075142624 284.76438159471456 1416200.2199926754 0.1490770060391183 0.11141524487775553 5.536950476468406e-08 7.256729360882627 0.39225565694204506 NAS(ph)ASFQELEDK ddPTM_PC-9_AZD4547_30min_R2 3 NASASFQELEDK 12 0 F2Z3H0;F2Z3N9;H7C3L7;Q99543-2;Q99543 F2Z3H0 DNAJC2 DnaJ homolog subfamily C member 2;DnaJ homolog subfamily C member 2, N-terminally processed 1 NAS(0.791)AS(0.209)FQELEDK;NAS(0.998)AS(0.002)FQELEDK;NAS(0.628)AS(0.372)FQELEDK 166.64 0.00088132 19684700.0 39091.0 52895.0 37502.5 28036.6 33915.8 47434.0 49416.0 45750.0 37095.0 32457.8 True False 51521.12485668869 69992.27433189811 37005.19234630179 21573.195031152023 29207.17659932215 44467.94448149204 53813.928268523276 38680.38873041331 39055.76596905658 31321.462301385407 1.644914415583011 2.234642612098038 1.1814643898240018 0.6887671726041283 0.9324972224566367 1.4197275993568519 1.718116726183087 1.2349483672958144 1.2469330324762349 1.0 14.934863948682542 -5.275843577407242 24.3776983288777 1.1879078275567172 1.9397784799718978 0.5178455214918716 0.29396858265238285 428.6691093970666 725480.9933032615 0.08449265349540297 0.17725784534307948 5.298542504871154e-06 5.275843577407242 0.7518706524151806 NAS(ph)ASFQELEDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NASASFQELEDK 12 0 F2Z3H0;F2Z3N9;H7C3L7;Q99543-2;Q99543 F2Z3H0 DNAJC2 DnaJ homolog subfamily C member 2;DnaJ homolog subfamily C member 2, N-terminally processed 1 NAS(0.986)AS(0.014)FQELEDK;NAS(0.831)AS(0.169)FQELEDK;NAS(0.999)AS(0.001)FQELEDK 198.16 9.158e-06 21610800.0 45372.0 75096.0 43187.0 41273.2 45647.0 29696.8 38580.7 25446.9 26641.9 29274.5 True False 53052.583462151844 82551.03458782597 44216.74186760958 38960.79641351983 36702.798029731275 28139.447529771405 34926.05679592056 24778.945838219228 27031.487385977034 34581.73511318551 1.5341215034037916 2.3871281853740896 1.2786154807700896 1.1266293112824362 1.0613347742559347 0.813708376334253 1.0099567497584516 0.7165327522496515 0.781669493954059 1.0 15.077722636510789 -5.523689177326922 2.834602151782282 0.9186725910443296 1.9604710070263913 0.7472097534776891 0.23460896486246507 0.11689609943901795 1.8860784891875497 0.0632344186705185 0.13850134828586735 2.994406953935167e-06 5.523689177326922 1.0417984159820617 NAS(ph)ASFQELEDK ddPTM_PC-9_Lapatinib_30min_R1 3 NASASFQELEDK 12 0 F2Z3H0;F2Z3N9;H7C3L7;Q99543-2;Q99543 F2Z3H0 DNAJC2 DnaJ homolog subfamily C member 2;DnaJ homolog subfamily C member 2, N-terminally processed 1 NAS(0.975)AS(0.025)FQELEDK;NAS(0.991)AS(0.009)FQELEDK;NAS(0.656)AS(0.344)FQELEDK 164.53 0.00011546 24426900.0 45002.0 63027.0 46848.0 49819.0 51416.0 42772.0 58848.0 59039.0 39522.2 41631.0 True False 44360.26322764391 62881.06485386736 42996.33827850963 53482.85545131217 48391.81196774531 40942.741266401856 61894.861494524564 61782.16747246588 35070.793648783576 48826.86288017938 0.9085216745647481 1.2878374965063155 0.8805877695649258 1.095357192669915 0.9910899270038772 0.838529015613289 1.2676395296256062 1.2653314963953077 0.7182684198828613 1.0 15.57538746752689 NAS(ph)ASFQELEDKK ddPTM_PC-9_AZD4547_30min_R2 3 NASASFQELEDKK 13 1 F2Z3H0;F2Z3N9;H7C3L7;Q99543-2;Q99543 F2Z3H0 DNAJC2 DnaJ homolog subfamily C member 2;DnaJ homolog subfamily C member 2, N-terminally processed 1 NAS(0.998)AS(0.002)FQELEDKK;NAS(0.997)AS(0.003)FQELEDKK;NAS(0.999)AS(0.001)FQELEDKK 113.59 0.00048843 23865000.0 74612.4 99892.1 68693.3 56925.8 51749.8 85934.0 74052.4 89773.0 82945.0 66688.4 True False 98337.59116566989 132180.2678285168 67782.38195859507 43802.436304842726 44565.23353657004 80560.53339529749 80642.92014149268 75900.64562831471 87329.30336442642 64353.65941436909 1.528080796967278 2.053966612487668 1.0532793717626632 0.6806518339975299 0.6925050407719219 1.2518407520009605 1.2531209705144828 1.1794301414872979 1.357021561153479 1.0 15.973734567915477 -5.274886330695048 24.149287505052857 1.0521820061529494 1.7910236729123794 0.5894580937247891 0.24449206773102525 313.5691927239066 563137.5456333549 0.06967954430456628 0.14648961721578618 5.310234125259375e-06 5.274886330695048 0.73884166675943 NAS(ph)ASFQELEDKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NASASFQELEDKK 13 1 F2Z3H0;F2Z3N9;H7C3L7;Q99543-2;Q99543 F2Z3H0 DNAJC2 DnaJ homolog subfamily C member 2;DnaJ homolog subfamily C member 2, N-terminally processed 1 NAS(0.942)AS(0.058)FQELEDKK;NAS(0.985)AS(0.015)FQELEDKK 90.42200000000001 0.0025756 22618000.0 69627.0 125806.0 76822.0 79363.0 76075.0 43957.0 72974.0 40627.0 47411.0 46854.0 True False 81413.47590406504 138295.18825711083 78653.72782905758 74916.54840831767 61168.64985895692 41651.817538124065 66061.37443399173 39560.58429786467 48104.29618220011 55348.259303940074 1.470931099332142 2.498636632774213 1.421069584088229 1.3535484105637372 1.1051594147352437 0.7525406952619195 1.1935583027321877 0.7147575153289143 0.8691203081571115 1.0 15.756250324685222 -5.8147460657859025 1.4312498230747412 0.9162453049321551 1.981253548167681 0.6555972823035747 0.288225654462974 0.23383405342899957 0.9687130091260402 0.09203301585453763 0.20249185914062498 1.5319829581596957e-06 5.8147460657859025 1.065008243235526 NAS(ph)ASFQELEDKK ddPTM_PC-9_Lapatinib_30min_R1 1 NASASFQELEDKK 13 1 F2Z3H0;F2Z3N9;H7C3L7;Q99543-2;Q99543 F2Z3H0 DNAJC2 DnaJ homolog subfamily C member 2;DnaJ homolog subfamily C member 2, N-terminally processed 1 NAS(0.914)AS(0.086)FQELEDKK 60.542 0.026133 17566000.0 64090.0 84322.0 50175.0 49792.0 82055.0 61652.0 56104.0 64052.0 42782.0 61410.0 True False 63176.064847333444 84126.75758972822 46049.80518110103 53453.86978124281 77228.68622633697 59015.287677831424 59008.79060101969 67028.08975332226 37963.44064556782 72024.63667631858 0.8771452070108878 1.1680275176922728 0.639361853195464 0.7421609083773169 1.07225374247156 0.8193764023142295 0.819286196002729 0.9306272526517421 0.527089651506011 1.0 16.136202857369923 NAS(ph)GEDEVLLGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NASGEDEVLLGAR 13 0 O15438-5;O15438-2;O15438;O15438-4 O15438-5 ABCC3 Canalicular multispecific organic anion transporter 2 1 NAS(1)GEDEVLLGAR 98.508 0.0096156 0.0 5105.3 6050.1 5625.1 4288.9 9188.8 5167.5 3225.1 4043.3 3490.0 4779.7 True False 5969.5264557287255 6650.713944282047 5759.22371731055 4048.6068378014065 7388.320602352718 4896.507203136152 2919.5951802980094 3937.167659230471 3541.034647568675 5646.221773915618 1.0572603582995463 1.1779051922839758 1.0200137273950127 0.7170470803157497 1.3085424020156697 0.8672183628629339 0.5170882932345906 0.6973101335514973 0.627151179914244 1.0 12.463070081151534 -7.0001564826026375 24.999998507003 0.6861618071547846 1.0466516775941 0.4474828484266533 0.1805442758459405 4.859155420625764 776433.0624802567 0.06227840846661313 0.054348457043723826 9.996397503973308e-08 7.0001564826026375 0.36048987043931535 NAS(ph)GEDEVLLGAR ddPTM_PC-9_Lapatinib_30min_R1 2 NASGEDEVLLGAR 13 0 O15438-5;O15438-2;O15438;O15438-4 O15438-5 ABCC3 Canalicular multispecific organic anion transporter 2 1 NAS(1)GEDEVLLGAR;NAS(1)GEDEVLLGAR 127.07 0.00096866 666180.0 13231.9 18294.0 15736.7 9643.7 12510.0 12868.5 9545.2 11004.1 15189.0 8855.1 True False 13043.21067956672 18251.641366980002 14442.889271418686 10352.929868440138 11774.186395606308 12318.144252938655 10039.403750977699 11515.39065844208 13478.254872739213 10385.692236320927 1.2558826492038633 1.7573832298968204 1.3906525383940125 0.9968454324338428 1.1336929814297334 1.186068677238436 0.9666571589583423 1.1087744944116833 1.2977714499956923 1.0 13.34230975871939 -5.607720252974916 5.102842938698779 1.1042775428790326 1.5223564357228752 0.578225075030171 0.14629919671141733 0.12633901950054735 5.591435569995281 0.03811811167452359 0.06779384762870906 2.46762832680427e-06 5.607720252974916 0.4180788928438426 NAS(ph)RDQVVYGSGTK ddPTM_PC-9_AZD4547_30min_R2 1 NASRDQVVYGSGTK 14 1 C9JFU4;A0A0G2JNC6;A0A0G2JMP8;A0A0G2JMM6;A0A087WVI4;A0A0G2JPL6;A0A0G2JP95;A0A087WT65;Q7Z404-1;Q7Z404 C9JFU4 TMC4 Transmembrane channel-like protein;Transmembrane channel-like protein 4 1 NAS(1)RDQVVYGSGTK 130.87 0.00059241 0.0 4303.3 6701.3 9547.4 9731.2 9191.3 5536.7 5271.9 6616.8 5035.3 5165.3 True False 5671.659885799507 8867.364173936086 9420.795237839664 7487.822185541281 7915.246648386585 5190.4892737419805 5741.088886976443 5594.325598937674 5301.45567823131 4984.464419194957 1.1378674635449677 1.7790003956670348 1.8900315952824516 1.502232046577763 1.5879833784960549 1.0413333985801223 1.151796543048388 1.1223523990650164 1.0635958515052557 1.0 12.283222780001271 -6.7571385588295545 24.566922809968727 1.088211427973684 1.6034783740278422 0.6390886302952987 0.1886792493970985 56.75201203732456 324175.64620798227 0.06423563054060927 0.062067856668936855 1.749288500468528e-07 6.7571385588295545 0.5152669460541581 NAS(ph)RDQVVYGSGTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NASRDQVVYGSGTK 14 1 C9JFU4;A0A0G2JNC6;A0A0G2JMP8;A0A0G2JMM6;A0A087WVI4;A0A0G2JPL6;A0A0G2JP95;A0A087WT65;Q7Z404-1;Q7Z404 C9JFU4 TMC4 Transmembrane channel-like protein;Transmembrane channel-like protein 4 1 NAS(1)RDQVVYGSGTK 115.38 0.003198 0.0 6230.7 7130.8 4692.3 6263.2 11509.0 6234.8 5262.6 5275.5 4942.3 4863.1 True False 7285.434448065531 7838.698698184562 4804.182227646846 5912.293209568372 9253.894068047779 5907.83611226189 4764.088430075441 5137.023714854286 5014.571787587009 5744.74153372158 1.2681918595118855 1.3644998042421008 0.8362747391586445 1.0291660947430386 1.610846025661469 1.0283902378519463 0.8292955221936941 0.8942132008376711 0.8728977201413708 1.0 12.488026269542798 -6.994554155219941 24.998700315864557 0.8957941181746488 1.2098056243217037 0.3823967286373623 0.19394233176455428 167.8924056265023 770690.3636727554 0.07176833290474434 0.06309996970510011 1.0126184704538474e-07 6.994554155219941 0.31401150614705486 NAS(ph)RDQVVYGSGTK ddPTM_PC-9_Lapatinib_30min_R1 3 NASRDQVVYGSGTK 14 1 C9JFU4;A0A0G2JNC6;A0A0G2JMP8;A0A0G2JMM6;A0A087WVI4;A0A0G2JPL6;A0A0G2JP95;A0A087WT65;Q7Z404-1;Q7Z404 C9JFU4 TMC4 Transmembrane channel-like protein;Transmembrane channel-like protein 4 1 NAS(1)RDQVVYGSGTK;NAS(1)RDQVVYGSGTK;NAS(1)RDQVVYGSGTK 139.0 3.7915e-05 0.0 42556.0 44622.0 19369.5 17176.0 17583.9 18069.0 19458.3 18086.800000000003 29722.9 8424.1 True False 41949.14363618539 44518.68050056753 17777.01447843221 18439.180337456335 16549.64957327752 17296.23099089626 20465.755563806888 18927.178757109654 26375.19400598726 9880.194460592329 4.245781173994271 4.505850636658277 1.7992575499740173 1.8662770668130033 1.675032777875644 1.7505962114291556 2.071391979726272 1.9156686472722468 2.6695015074031283 1.0 13.270323721671568 -5.262183010912556 24.99996698598775 1.8757908019610645 4.375816109202803 0.8699516802633444 0.3914817947069184 18.863281164280423 634187.2060180783 0.09702682462338207 0.22324585431652624 5.467854999140788e-06 5.262183010912556 2.500025307241738 NAS(ph)VPNLR ddPTM_PC-9_AZD4547_30min_R2 4 NASVPNLR 8 0 E9PPF9;E9PLD2;Q9H019-3;Q9H019;E9PNJ0;E9PPQ0;E9PRW1;E9PSD6;C9JF50;E9PLU1;E9PRK5;Q9H019-2 E9PPF9 MTFR1L Mitochondrial fission regulator 1-like 1 NAS(1)VPNLR;NAS(1)VPNLR;NAS(1)VPNLR;NAS(1)VPNLR 125.74 0.0034625 194344000.0 169207.0 172572.0 207988.0 304587.0 261019.0 208814.0 224237.0 244476.0 204812.0 221234.0 True False 223011.30627575982 228352.52417060852 205229.94322305516 234369.17297223976 224781.01736590243 195756.82757006117 244193.65859537094 206697.85169959604 215637.94418801516 213488.66499838873 1.044604903391208 1.0696236456972175 0.961315408593726 1.0978061667770915 1.0528943884097965 0.9169424876563756 1.1438249360789903 0.9681912231787859 1.0100674159428682 1.0 17.703799947632795 -7.559371301571682 0.3059274181287187 0.9937820911396011 1.048973161913556 0.04337210274990422 0.06365589164855605 6.300984196089806 1.8581694979730088 0.10197206775439524 0.12574578084914417 2.758218699248053e-08 7.559371301571682 0.05519107077395491 NAS(ph)VPNLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 NASVPNLR 8 0 E9PPF9;E9PLD2;Q9H019-3;Q9H019;E9PNJ0;E9PPQ0;E9PRW1;E9PSD6;C9JF50;E9PLU1;E9PRK5;Q9H019-2 E9PPF9 MTFR1L Mitochondrial fission regulator 1-like 1 NAS(1)VPNLR;NAS(1)VPNLR;NAS(1)VPNLR;NAS(1)VPNLR;NAS(1)VPNLR 99.973 0.0050353 187569200.0 174271.0 178931.0 151805.0 201958.0 202728.0 192783.0 198822.0 161414.0 142903.0 149001.5 True False 203771.63829085501 196694.08716621684 155424.60692366847 190642.94801666995 163004.9036951244 182673.12010492448 179988.1408133739 157177.05353226955 144992.68602908525 176014.2924547748 1.1576993859360154 1.1174892926195497 0.8830226497862572 1.0831106119729104 0.926089020509553 1.0378311758510212 1.0225768504544603 0.8929789242692021 0.8237551849168142 1.0 17.42533305566552 -1.5228787452816295 0.49654802054313524 0.9443743541673968 7.956097751069606 0.41655039447613074 0.07970171597283411 107.82869556403848 1.1566962219251902 0.045153311992438515 787.2699673138363 0.029999999999910758 1.5228787452816295 7.01172339690221 NAS(ph)VPNLR ddPTM_PC-9_Lapatinib_30min_R1 3 NASVPNLR 8 0 E9PPF9;E9PLD2;Q9H019-3;Q9H019;E9PNJ0;E9PPQ0;E9PRW1;E9PSD6;C9JF50;E9PLU1;E9PRK5;Q9H019-2 E9PPF9 MTFR1L Mitochondrial fission regulator 1-like 1 NAS(1)VPNLR;NAS(1)VPNLR;NAS(1)VPNLR 84.81700000000001 0.013691 182376000.0 160145.0 159265.0 165197.0 129622.0 139624.0 134226.0 137492.0 141680.0 137592.0 111166.0 True False 157861.30293300416 158896.2316777122 151615.14033886103 139154.83428631644 131411.5908313457 128485.46687608832 144610.6630064772 148262.97002826867 122094.94005200699 130380.89498061565 1.2107702049174778 1.218707938009906 1.1628631661210975 1.0672946700281913 1.007905267492475 0.9854623784810718 1.1091399781231535 1.1371525717039421 0.936448089807632 1.0 16.99237295799324 -5.697968884037112 2.493494713006674 1.0376577561994864 1.2131535258648658 0.6555351193694556 0.05521285899205542 0.18441268963358126 2.325042960349595 0.016737468269425175 0.03237156059444718 2.004615647222701e-06 5.697968884037112 0.1754957696653794 NAS(ph)VYSPSGPVNR ddPTM_PC-9_AZD4547_30min_R2 2 NASVYSPSGPVNR 13 0 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 NAS(0.874)VYS(0.097)PS(0.03)GPVNR;NAS(0.487)VY(0.003)S(0.43)PS(0.081)GPVNR 138.31 6.3485e-05 10769900.0 29389.0 31316.0 33596.0 44894.0 37835.0 37064.0 34279.0 39383.0 32180.0 36117.0 True False 38734.09067082511 41438.28458224259 33150.495088763564 34544.38190538579 32582.26332963853 34746.38222081253 37329.76459277783 33297.262281308576 33880.969103227915 34852.55482315924 1.111370195595722 1.188959741760658 0.9511639894684372 0.9911578098266508 0.9348601126936003 0.9969536637160338 1.0710768488045674 0.9553750779607931 0.9721229698981575 1.0 15.088976794484074 -5.262573330978849 24.999956894032593 0.9845555310452365 1.1501649766122684 0.7397766581652812 0.03939866327363518 46.40404491342341 1023083.7400850082 0.010402631932170382 0.02383259548489558 5.462942998540164e-06 5.262573330978849 0.16560944556703183 NAS(ph)VYSPSGPVNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NASVYSPSGPVNR 13 0 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 NAS(0.932)VYS(0.065)PS(0.003)GPVNR 104.7 0.0013109000000000003 3538200.0 10851.0 10387.0 8238.2 7810.2 8193.7 7297.7 8908.7 8587.4 6317.0 3806.4 True False 12687.859982980903 11418.15271470846 8434.629931547479 7372.619815010043 6588.203303967604 6914.995765133372 8064.803442597397 8361.989849102405 6409.374174410123 4496.470188554178 2.8217378189847695 2.539359149711147 1.8758336156698951 1.6396461014635746 1.4651944809370603 1.5378720363220868 1.7935854357772585 1.8596787031720918 1.4254234778927848 1.0 12.13457718837657 -5.252192656170006 1.7551023054112356 1.569979316860767 2.8684936860416244 0.8088613212158269 0.2223512045312713 0.18461294270994727 0.9734225072334923 0.06301432718477029 0.2901367076347085 5.5950934404723555e-06 5.252192656170006 1.2985143691808574 NAS(ph)VYSPSGPVNR ddPTM_PC-9_Lapatinib_30min_R1 1 NASVYSPSGPVNR 13 0 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 NAS(0.573)VYS(0.37)PS(0.056)GPVNR 110.25 0.00069697 4286000.0 13142.0 18410.0 16682.0 17460.0 18203.0 14038.0 15306.0 13996.0 14288.0 15602.0 True False 12954.59267005237 18367.372776107037 15310.470354382203 18744.066644852566 17132.33532847495 13437.627464176303 16098.469787166827 14646.305254910027 12678.73498068984 18298.78491164178 0.7079482453400824 1.0037482196111078 0.8366932792702321 1.0243339508803941 0.9362553530849621 0.7343453420028571 0.879756216869072 0.8003976944716135 0.6928730536978751 1.0 14.15946023242219 -6.740563359365923 24.9973003216121 0.8126419010462665 0.9106507156946931 0.10629090905666416 0.11359439902738591 457.23503595683974 547500.0023496891 0.03569198147215853 0.03565608994986284 1.8173419041416177e-07 6.740563359365923 0.09800881464842659 NASAS(ph)FQELEDK ddPTM_PC-9_Lapatinib_30min_R1 1 NASASFQELEDK 12 0 F2Z3H0;F2Z3N9;H7C3L7;Q99543-2;Q99543 F2Z3H0 DNAJC2 DnaJ homolog subfamily C member 2;DnaJ homolog subfamily C member 2, N-terminally processed 1 NAS(0.087)AS(0.913)FQELEDK 190.18 0.00017441 8640100.0 13207.0 19554.0 13440.0 12989.0 19491.0 15929.0 16452.0 18810.0 10794.0 13580.0 True False 13018.66575813283 19508.72391439418 12335.01507990031 13944.25439003379 18344.57770078037 15247.753802312602 17303.80405974576 19683.981269281045 9578.26605414097 15927.284905787423 0.8173813575345977 1.2248618662748594 0.7744581171784146 0.8754947545998208 1.1517705503035602 0.9573354085461293 1.086425223263141 1.2358654589099847 0.6013746919702906 1.0 13.959212733870087 -4.503734499475374 19.310169580759055 0.9954812101899645 0.40019104544735146 0.06785994786896143 0.1905625016521698 15521745.034452258 367866001.6672423 0.045290376418985166 281159687.42812186 3.1352018051607336e-05 4.503734499475374 -0.595290164742613 NASGVVNS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NASGVVNSSPR 11 0 A0A3B3ITD2;Q8N5G2 A0A3B3ITD2 TMEM57 Macoilin 1 NAS(0.054)GVVNS(0.473)S(0.473)PR 68.676 0.036618 3259100.0 22871.0 22067.0 23046.0 25456.0 41778.0 21204.0 19249.0 20795.0 21482.0 16817.0 True False 26742.60857715936 24257.665924277608 23595.504042441717 24029.782849465508 33591.90080588236 20092.024912491335 17425.59536930836 20249.15328412377 21796.133610048797 19865.788976701242 1.3461639307919413 1.221077398573356 1.187745629942748 1.2096062672188772 1.690942194406636 1.0113882180091325 0.8771660360303455 1.0192977136660488 1.0971692911674173 1.0 14.277998471247342 -6.952208631017642 24.999969439564197 0.9920522444001232 1.3143687171424399 0.5710188627513468 0.14268296449605114 90.89162214020737 47545.649688856574 0.05135039421654975 0.04528677896474351 1.1163268459469008e-07 6.952208631017642 0.3223164727423167 NASGVVNS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 2 NASGVVNSSPR 11 0 A0A3B3ITD2;Q8N5G2 A0A3B3ITD2 TMEM57 Macoilin 1 NAS(0.001)GVVNS(0.499)S(0.499)PR;NAS(0.007)GVVNS(0.497)S(0.497)PR 96.756 0.0056729 9108100.0 133000.0 131613.0 68895.0 42870.0 52250.0 48744.0 55175.0 47605.0 90508.0 23301.0 True False 131103.3956107869 131308.25818477862 63230.71904239078 46022.802810127716 49176.75772745242 46659.33274781377 58031.691526651615 49816.90209059669 80314.0359485076 27328.54680336913 4.797305782634009 4.804802067579774 2.3137241616738855 1.6840559851669066 1.7994647897410263 1.7073477445958267 2.123482523391889 1.822888807408345 2.9388330278361634 1.0 14.738121126080417 -5.296624678048761 3.9529855666123335 1.9104720973415281 4.859789307138707 0.8658974211135153 0.45520981149384365 0.06463457205017685 2.232847075881172 0.11570525966885155 0.2838245715963074 5.0509761978191244e-06 5.296624678048761 2.9493172097971785 NASGVVNSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 NASGVVNSSPR 11 0 A0A3B3ITD2;Q8N5G2 A0A3B3ITD2 TMEM57 Macoilin 1 NAS(0.11)GVVNS(0.204)S(0.686)PR 77.204 0.019762000000000002 4975800.0 32407.0 22464.0 55041.0 52570.0 39510.0 37760.0 34709.0 51367.0 36960.0 36132.0 True False 42711.75189252543 29725.04869253729 54311.12037684951 40450.79869840356 34024.71849224308 35398.86123078679 37798.03375975746 43429.41044623256 38913.63014466452 34867.02967772485 1.2249896904700277 0.8525259813435566 1.5576640992607038 1.1601446716938424 0.9758421869236573 1.0152531362142874 1.0840623393826148 1.245572417485791 1.11605807848682 1.0 15.089575845707598 -6.009273554960821 24.98295044845755 1.0814199556582433 1.2063227931339378 0.11681872389324277 0.1729936661773638 1125.3223276365493 3031632.6859859484 0.05049562797906739 0.07053740040089349 9.788732150222706e-07 6.009273554960821 0.12490283747569442 NASGVVNSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NASGVVNSSPR 11 0 A0A3B3ITD2;Q8N5G2 A0A3B3ITD2 TMEM57 Macoilin 1 NAS(0.002)GVVNS(0.241)S(0.757)PR 76.24 0.020834000000000002 4929300.0 22890.0 21325.0 29359.0 23049.0 37407.0 23327.0 18176.0 24810.0 22389.0 19229.0 True False 26764.824901892243 23442.005067984763 30059.029904627525 21757.639255866223 30077.366878396326 22103.69105516345 16454.237697155622 24158.76378836791 22716.396769173363 22715.065483319744 1.1782851747245167 1.0320025308841319 1.323308089369174 0.9578506067633138 1.3241153498097071 0.9730850686472711 0.7243755343447454 1.0635568630039085 1.0000586080570446 1.0 14.471361843972257 -6.9393858028254085 11.680362008318891 0.9375245035605172 1.1530356724427442 0.3801539189597304 0.13445302117433552 0.68876206910983 130.52431454028334 0.0454911552687167 0.04011884755445229 1.1497785364594154e-07 6.9393858028254085 0.215511168882227 NASVYS(ph)PSGPVNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NASVYSPSGPVNR 13 0 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 NAS(0.012)VYS(0.97)PS(0.018)GPVNR 149.59 9.7875e-08 0.0 13630.0 15527.0 15218.0 18041.0 16310.0 13579.0 16453.0 11428.0 12288.0 7754.9 True False 15937.289795228988 17068.41794563186 15580.854834586396 17030.22125971116 13114.172582314655 12866.89333553669 14894.452730595374 11128.027108966879 12467.688753387929 9160.801982245373 1.7397264809475395 1.8632012763415586 1.700817773900558 1.8590316975214152 1.431552893265387 1.4045597056321186 1.6258896065499981 1.2147437670341745 1.3609822346942615 1.0 13.161258189224627 -7.312303606963222 0.27918619264887384 0.9472965118530767 1.9820711253599022 0.7897286124732119 0.12431237526087033 0.9053701201086429 0.20765089015939187 0.22079381174967708 0.341838854313615 4.8718778736678156e-08 7.312303606963222 1.0347746135068254 NASVYSPS(ph)GPVNR ddPTM_PC-9_Lapatinib_30min_R1 1 NASVYSPSGPVNR 13 0 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 NAS(0.003)VYS(0.487)PS(0.51)GPVNR 112.24 0.00047771 4663900.0 16215.0 21334.0 20507.0 20947.0 24187.0 16487.0 16337.0 20774.0 17183.0 14859.0 True False 15983.771126533189 21284.602433757056 18820.99361930918 22487.512257143557 22764.368213471615 15781.889443074142 17182.849922445086 21739.235879215554 15247.669594988358 17427.358351627045 0.9171654592757553 1.221332688770349 1.0799682453050623 1.2903569091436102 1.3062431926951394 0.905581277704129 0.9859698512965317 1.2474200300808036 0.8749271855975127 1.0 14.089066281093563 -6.767441041520589 24.999957716299935 1.017192826935633 1.1687142955382397 0.24451939015393476 0.1395006322293049 234.20034638291787 975556.1511343109 0.04873575174531794 0.04408486043551489 1.7082796150905409e-07 6.767441041520589 0.15152146860260673 NAT(ph)SPQVQR ddPTM_PC-9_AZD4547_30min_R2 1 NATSPQVQR 9 0 A0A087WZ06;Q13188;Q13188-2 A0A087WZ06 STK3 Serine/threonine-protein kinase 3;Serine/threonine-protein kinase 3 36kDa subunit;Serine/threonine-protein kinase 3 20kDa subunit 1 NAT(0.848)S(0.152)PQVQR 120.86 0.004038900000000001 5313200.0 34806.0 47706.0 35073.0 36159.0 36280.0 40305.0 36820.0 52748.0 53664.0 38169.0 True False 45873.58399022557 63126.03155832371 34607.90910370888 27823.101200981066 31243.1482383847 37784.72197846561 40096.9086702086 44597.00862845553 56500.56948277266 36832.71492773941 1.2454575797690468 1.7138576855430852 0.9395970178034585 0.7553909956289148 0.8482445103403142 1.0258467792177117 1.0886221324947964 1.210798843255203 1.5339778670570117 1.0 15.168700121300512 -5.272449802183997 24.711898347796783 1.0405834796633686 1.4796576440591984 0.36364371551966657 0.2268942298594444 604.0713072511085 1355784.9923346122 0.06372750126465582 0.13477170112648226 5.3401099353052004e-06 5.272449802183997 0.4390741643958298 NATDLQNS(ph)SMSEEELTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NATDLQNSSMSEEELTK 17 0 Q5QNY5;P40855;H0YJ60;P40855-5 Q5QNY5 PEX19 Peroxisomal biogenesis factor 19 1 NATDLQNS(0.381)S(0.236)MS(0.381)EEELT(0.001)K 81.594 0.0044017 4989800.0 45469.0 54421.0 45113.0 62025.0 69403.0 63538.0 65718.0 62152.0 57651.0 51240.0 True False 53166.003646314486 59823.55722414067 46188.665012005265 58549.94033776313 55803.98036360412 60205.955427743625 59492.71528288252 60520.5758554874 58494.03681002338 60529.40638438315 0.878349992542328 0.988338739756341 0.7630781098147716 0.9672974482179834 0.921931730326729 0.9946563005329095 0.9828729346044255 0.9998541117545465 0.966373871875854 1.0 15.885348582067806 -6.420230060262313 1.6810397380648376 0.9883470712117155 0.8915677274730843 0.36870984580931476 0.056641134164931536 0.40587147861066714 2.294370829414504 0.0206308290614499 0.02442849953118401 3.79988050659893e-07 6.420230060262313 -0.09677934373863117 NATDLQNSS(ph)MSEEELTK ddPTM_PC-9_AZD4547_30min_R2 4 NATDLQNSSMSEEELTK 17 0 Q5QNY5;P40855;H0YJ60;P40855-5 Q5QNY5 PEX19 Peroxisomal biogenesis factor 19 1 NATDLQNS(0.092)S(0.688)MS(0.22)EEELTK;NAT(0.001)DLQNS(0.258)S(0.467)MS(0.273)EEELTK;NATDLQNS(0.361)S(0.49)MS(0.149)EEELTK;NATDLQNS(0.032)S(0.765)MS(0.203)EEELTK 117.53 0.00011001 102262000.0 295787.0 280875.0 365483.0 463563.0 439905.0 412721.0 396584.0 441104.0 371077.0 388562.0 True False 389841.1132482008 371662.3509400114 360636.4566176504 356695.71232695563 378831.78406302666 386913.49062583566 431879.2077149915 372941.5123615354 390691.3726512902 374958.56264906854 1.0396911874581223 0.9912091307216202 0.9618034965511043 0.951293683779118 1.010329731868487 1.0318833310334508 1.1518051612524347 0.9946206048122151 1.0419587964362513 1.0 18.516371644008387 -6.696023898550764 3.2630184909507127 1.0512823216954663 0.9846919068462535 0.25705439265719154 0.04592881116880042 0.31470198007749095 6.767309511173513 0.016603101947390727 0.016062085268161348 2.013613440793623e-07 6.696023898550764 -0.0665904148492128 NATDLQNSS(ph)MSEEELTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 NATDLQNSSMSEEELTK 17 0 Q5QNY5;P40855;H0YJ60;P40855-5 Q5QNY5 PEX19 Peroxisomal biogenesis factor 19 1 NATDLQNS(0.056)S(0.569)MS(0.374)EEELT(0.001)K;NAT(0.002)DLQNS(0.053)S(0.473)MS(0.473)EEELTK;NATDLQNS(0.04)S(0.876)MS(0.084)EEELTK;NATDLQNS(0.232)S(0.728)MS(0.04)EEELTK;NAT(0.001)DLQNS(0.154)S(0.64)MS(0.205)EEELTK 144.08 2.4421e-05 90864800.0 185259.0 185967.0 187088.0 234469.0 262673.0 222966.0 257200.0 243463.0 208517.0 180515.0 True False 216619.68966796194 204428.57474691284 191548.88745519108 221332.46208875423 211204.1112639079 211273.2704507896 232836.15403325396 237072.35422037172 211566.1666495921 213240.94054404614 1.0158447487395972 0.9586741374585475 0.8982744447031997 1.0379454410774216 0.990448225960073 0.9907725501105163 1.0918923610035396 1.1117581530803793 0.9921460959130027 1.0 17.702124924961332 -7.140265324412051 5.647251195814516 1.057926123877853 0.9789607241378057 0.30701163455429614 0.048646448961790704 0.25968280048037656 10.95081537928834 0.01909197337668143 0.014731472617022184 7.239935141049223e-08 7.140265324412051 -0.07896539974004735 NATDLQNSS(ph)MSEEELTK ddPTM_PC-9_Lapatinib_30min_R1 6 NATDLQNSSMSEEELTK 17 0 Q5QNY5;P40855;H0YJ60;P40855-5 Q5QNY5 PEX19 Peroxisomal biogenesis factor 19 1 NATDLQNS(0.068)S(0.712)MS(0.22)EEELTK;NATDLQNS(0.049)S(0.764)MS(0.187)EEELTK;NATDLQNS(0.161)S(0.766)MS(0.072)EEELTK;NATDLQNS(0.042)S(0.828)MS(0.13)EEELTK;NATDLQNS(0.192)S(0.616)MS(0.192)EEELTK;NATDLQNS(0.194)S(0.782)MS(0.025)EEELTK 149.99 8.2133e-12 77741100.0 329628.0 309815.0 310635.0 296196.0 303856.0 302370.0 275434.0 286293.0 285475.0 233195.0 True False 324927.44427362824 309097.6424024773 285095.7893857755 317979.24192088994 285983.7874838808 289438.3399588969 289694.62481108727 299595.21794398036 253321.79931498005 273502.44503719395 1.1880239104606212 1.1301458104348672 1.0423884486553858 1.1626193757706536 1.0456352134072862 1.0582660053351107 1.0592030530904077 1.0954023387368184 0.9262140207943315 1.0 18.06119420481211 -1.5228787452883121 0.16835588667150678 0.9733997229384672 1.764212622399925 0.5394772712093087 0.04984461918410612 49.26999794600269 0.5295839662033133 0.12932676115593644 9.786039799555187 0.029999999999449137 1.5228787452883121 0.7908128994614578 NATS(ph)PQVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NATSPQVQR 9 0 A0A087WZ06;Q13188;Q13188-2 A0A087WZ06 STK3 Serine/threonine-protein kinase 3;Serine/threonine-protein kinase 3 36kDa subunit;Serine/threonine-protein kinase 3 20kDa subunit 1 NAT(0.092)S(0.908)PQVQR;NAT(0.009)S(0.991)PQVQR 107.09 0.0025256 8397500.0 48767.0 92890.0 62019.0 51779.0 61005.0 59500.0 85983.0 54994.0 57040.0 46929.0 True False 57022.28990784533 102111.50531137672 63497.7681683673 48877.99049978296 49051.50817805671 56379.7152562363 77838.06777698781 53550.465770959454 57874.10209092185 55436.85621024038 1.0285989106523699 1.8419425683903505 1.1454070903219418 0.8816876324013868 0.8848176381436984 1.0170078014961776 1.4040851718176877 0.9659722688435484 1.043964359584865 1.0 15.758557825002626 -5.5051294652958145 24.661713717802137 1.0342916025564775 1.4498718348716635 0.3314453629136326 0.22799206034171238 635.0673666382211 882391.7018187051 0.05820815673094913 0.11722608970043012 3.1251476065593133e-06 5.5051294652958145 0.41558023231518604 NAVALS(ph)ASPQLK ddPTM_PC-9_AZD4547_30min_R2 3 NAVALSASPQLK 12 0 Q92547;A0A2R8YD63 Q92547 TOPBP1 DNA topoisomerase 2-binding protein 1 1 NAVALS(0.719)AS(0.281)PQLK;NAVALS(0.737)AS(0.263)PQLK;NAVALS(0.637)AS(0.363)PQLK 121.76 0.00043197 12025000.0 191528.0 146593.0 157407.0 244812.0 204775.0 197049.0 169052.0 186194.0 166061.0 183618.0 True False 252429.91997011783 193976.32046764236 155319.68033209318 188374.37570769605 176345.52592379393 184727.49487990764 184097.30050288202 157421.99561247183 174838.64543974923 177189.58970896984 1.4246317765322931 1.094738809352425 0.8765733956899074 1.0631232682297926 0.9952363804975096 1.0425414674943299 1.0389848568714333 0.8884381744493801 0.9867320406741616 1.0 17.43493431920767 -4.801866467955249 3.3218121682096156 0.98892586664026 1.4730954476074083 0.8335159819890596 0.058787898344209916 0.11148429837200083 1.9751284245817462 0.014869989163015341 0.1356363909578857 1.5780964106733136e-05 4.801866467955249 0.48416958096714824 NAVALS(ph)ASPQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NAVALSASPQLK 12 0 Q92547;A0A2R8YD63 Q92547 TOPBP1 DNA topoisomerase 2-binding protein 1 1 NAVALS(0.705)AS(0.295)PQLK 105.14 0.0032628999999999996 0.0 33808.0 30136.0 28262.0 36271.0 35246.0 27281.0 31811.0 28945.0 24331.0 22296.0 True False 39531.02666156284 33127.702918114366 28935.87326423186 34238.85346216859 28339.79931552803 25850.336334544267 28797.631788304225 28185.224419762555 24686.794845270317 26338.088304961115 1.5009072110262713 1.2577869181141117 1.098632251862464 1.29997489057394 1.0760006188524271 0.981481117202991 1.09338352331668 1.070131745835688 0.9373039743594543 1.0 14.684863013942607 -1.522878745661615 0.37926679843189753 1.0049784119277698 7.62024535156674 0.7758687116518598 0.07745720654086577 32.91407565814351 0.4497383681493966 0.06115759756373821 159.92176350330598 0.029999999973662282 1.522878745661615 6.61526693963897 NAVALSAS(ph)PQLK ddPTM_PC-9_AZD4547_30min_R2 2 NAVALSASPQLK 12 0 Q92547;A0A2R8YD63 Q92547 TOPBP1 DNA topoisomerase 2-binding protein 1 1 NAVALS(0.345)AS(0.655)PQLK;NAVALS(0.437)AS(0.563)PQLK 120.54 0.000488 23489300.0 120811.0 99221.0 106242.0 150736.0 143488.0 123475.0 112791.0 125379.0 103149.0 129245.0 True False 159226.38497509467 131292.24787759272 104833.16166271036 115986.14404798474 123567.16798316821 115754.08873070414 122829.18049488065 106004.55647279763 108601.24555714284 124720.17188911614 1.276669062937603 1.0526945712865081 0.8405469626510254 0.929971008628047 0.9907552732771004 0.9281104008870081 0.9848381271001078 0.8499391467086989 0.8707592678247428 1.0 16.928335295906223 -4.869745795150047 2.9990906977284983 0.9241672843688059 1.3015388243375148 0.7929119577748783 0.05512817532465898 0.13652511230919698 2.0018243341368596 0.014415399435952563 0.11241665566424758 1.3497526998685296e-05 4.869745795150047 0.37737153996870887 NAVALSAS(ph)PQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NAVALSASPQLK 12 0 Q92547;A0A2R8YD63 Q92547 TOPBP1 DNA topoisomerase 2-binding protein 1 1 NAVALS(0.13)AS(0.87)PQLK 100.11 0.0031341999999999997 13561000.0 89279.0 80741.0 66725.0 97876.0 92067.0 71789.0 64823.0 71868.0 67187.0 51413.0 True False 104392.1713593724 88756.43288132049 68315.97705597154 92392.32503827335 74027.13225848942 68024.2584626882 58682.49616212148 69981.54115044023 68169.48276968398 60733.76991491591 1.7188488629245162 1.4614016716838512 1.1248433474766644 1.52126774227434 1.2188792555146282 1.120040112082385 0.9662251535567753 1.1522673670427481 1.1224312744818083 1.0 15.890211303632023 -1.5228787452804953 0.3186850861899406 1.0359294976577391 7.287550023065135 0.7151710021560825 0.12397238144499417 32.35063988694724 0.4617874817668446 0.12236238003096048 117.70493088837496 0.029999999999989105 1.5228787452804953 6.251620525407396 NAVALSAS(ph)PQLK ddPTM_PC-9_Lapatinib_30min_R1 2 NAVALSASPQLK 12 0 Q92547;A0A2R8YD63 Q92547 TOPBP1 DNA topoisomerase 2-binding protein 1 1 NAVALS(0.162)AS(0.838)PQLK;NAVALS(0.199)AS(0.801)PQLK 124.16 0.00033048 23208500.0 136158.0 136170.0 135119.0 130048.0 114891.0 119960.0 114064.0 106936.0 112047.0 76655.0 True False 134216.36195168056 135854.70673125982 124010.03739442353 139612.16374741076 108133.33726439692 114829.59044041809 119969.67580056173 111904.63694906107 99427.08695278245 89904.71461363284 1.4928734552851632 1.5110965794741458 1.379349658439593 1.5528903500489 1.2027549136783529 1.2772365824628926 1.334409172156695 1.2447026546936197 1.105916273468774 1.0 16.45610915236773 -7.003613097170154 0.21870674439251683 0.9268447262150812 1.6827120896926184 0.7867836608509078 0.07902222945094646 1.804602525008319 0.23844877214348356 0.22429596613157046 0.4559950304677882 9.917150472838941e-08 7.003613097170154 0.7558673634775372 NAVASVQNGPGGGPSSSSIGSAS(ph)KSDESSTEETDKSR ddPTM_PC-9_Lapatinib_30min_R1 1 NAVASVQNGPGGGPSSSSIGSASKSDESSTEETDKSR 37 2 A0A0C4DG98;Q8NI27;Q8NI27-2;H0Y815 A0A0C4DG98 THOC2 THO complex subunit 2 1 NAVASVQNGPGGGPS(0.01)S(0.01)S(0.01)S(0.01)IGS(0.096)AS(0.378)KS(0.378)DES(0.007)S(0.025)T(0.025)EET(0.009)DKS(0.041)R 67.064 1.4802e-06 4596400.0 56944.0 29061.0 28324.0 31262.0 28860.0 30765.0 24957.0 24283.0 27733.0 19888.0 True False 56131.96811774933 28993.7110400025 25995.310053801793 33561.11176697487 27162.511540943073 29449.252666717763 26249.151344461137 25411.276829449864 24609.41749856323 23325.614300905752 2.4064518684753216 1.242998819494184 1.1144533952442306 1.438809342126165 1.1644928699643435 1.262528492789758 1.1253359078068037 1.0894151168598858 1.0550383445896054 1.0 14.509627455790477 -4.761453394809088 5.217854653890824 1.1727210972869617 2.4766528971831256 0.9113231753435097 0.11628162027703479 0.044359660042363115 3.444417154504838 0.029406454996575876 0.21111330422317745 1.731994885336533e-05 4.761453394809088 1.303931799896164 up NAWGS(ph)IER ddPTM_PC-9_AZD4547_30min_R2 1 NAWGSIER 8 0 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 NAWGS(1)IER 86.014 0.012794 4275500.0 6584.4 7975.8 15193.0 21755.0 19987.0 18350.0 17059.0 22057.0 17877.0 14401.0 True False 8678.10223597199 10553.821374730189 14991.530893070149 16739.72086139947 17212.15005073305 17202.571599177354 18577.217952338087 18648.59746943663 18821.941723381162 13896.825373323254 0.6244665240329439 0.7594411738805906 1.078773783964237 1.204571577443401 1.2385670531468278 1.2378777984934535 1.3367958115095444 1.3419322016692399 1.3544058601694962 1.0 13.76246772715586 -5.241039857393018 1.2808467636965943 1.2748220800382053 0.5412595940863835 0.8389023044682538 0.096488168635074 0.24180804682102533 0.58335213479271 0.029060450957566687 0.18780716747677278 5.740637750643325e-06 5.241039857393018 -0.7335624859518218 NAWGS(ph)IER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NAWGSIER 8 0 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 NAWGS(1)IER 75.229 0.026667000000000003 3000600.0 8305.9 10689.0 10238.0 14654.0 19126.0 15795.0 13585.0 13031.0 18117.0 14769.0 True False 9711.924820997247 11750.133278859985 10482.11274783122 13832.983888909013 15378.397597139798 14966.682394491636 12298.13045311726 12688.950057485778 18381.92685100334 17446.502788660335 0.5566688601517139 0.6734950506239676 0.6008145514781481 0.792880043437703 0.8814601862291428 0.8578614623109164 0.7049051951609837 0.7273062235563443 1.053616708957339 1.0 14.090650251794823 -3.7193442576239604 0.17127053761074185 1.026447486889609 2.2496424299315328e-17 0.6153304544851919 0.09634189192670842 22.14166122001327 0.4717771831324257 0.3042169919505365 5.134146442165026 0.00019083399512273585 3.7193442576239604 -1.026447486889609 NAWGS(ph)IER ddPTM_PC-9_Lapatinib_30min_R1 2 NAWGSIER 8 0 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 NAWGS(1)IER;NAWGS(1)IER 96.113 0.0062194 8229400.0 40859.0 31253.0 31630.0 29329.0 30610.0 31838.0 25011.0 24671.0 29823.0 31193.0 True False 40276.34316737706 31180.63559867858 29029.503495330846 31485.952498675877 28809.57998157546 30476.36295800296 26305.94720023713 25817.30472591348 26464.019689887544 36584.66848794015 1.10090769800617 0.8522869520864192 0.7934882204795759 0.860632439762437 0.7874768631857991 0.8330364663014305 0.7190429293874476 0.705686447163624 0.7233636597967589 1.0 15.158951565479414 NCASPSS(ph)AGQLILPECMK ddPTM_PC-9_AZD4547_30min_R2 2 NCASPSSAGQLILPECMK 18 0 G5EA31;P53992;P53992-2 G5EA31 SEC24C Protein transport protein Sec24C 1 NCASPS(0.065)S(0.935)AGQLILPECMK;NCAS(0.001)PS(0.231)S(0.768)AGQLILPECMK 151.31 5.1168e-05 9967400.0 54410.0 56888.0 67747.0 95622.0 79985.0 72603.0 61501.0 74180.0 65913.0 79636.0 True False 71711.24820169434 75275.93349452727 66848.63051489652 73577.82524517307 68880.46339159872 68063.12293270174 66974.46985677617 62717.185486820956 69397.02661594356 76847.96787931187 0.9331573778803801 0.9795435789889273 0.8698815643359744 0.9574465958647795 0.896321207865562 0.8856853969072215 0.8715190746742735 0.8161202855138211 0.9030430931489319 1.0 16.2297194902241 -6.442734004891358 5.0507520907772765 0.8830289634148397 0.9334112527346803 0.10487678819842627 0.05045341942133835 0.38576234940142845 17.24760011370469 0.015418064763432637 0.017334408204652464 3.6079955656598665e-07 6.442734004891358 0.05038228931984057 NCASPSS(ph)AGQLILPECMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NCASPSSAGQLILPECMK 18 0 G5EA31;P53992;P53992-2 G5EA31 SEC24C Protein transport protein Sec24C 1 NCAS(0.004)PS(0.241)S(0.755)AGQLILPECMK;NCAS(0.005)PS(0.062)S(0.933)AGQLILPECMK 154.52 1.5467999999999998e-05 4144900.0 59400.0 69080.0 56880.0 72975.0 77340.0 62360.0 64092.0 63959.0 58641.0 49238.0 True False 69455.24679652255 75937.80586618473 58236.23491860125 68886.44733814202 62185.78218983539 59089.73182149407 58020.741774103124 62280.144020162115 59498.513687127444 58164.45963220649 1.1941183196012053 1.305570555393536 1.0012340059006586 1.1843391612977114 1.0691371085205137 1.0159078618651043 0.9975291121242741 1.0707594365009232 1.0229358969954614 1.0 15.82785026852171 -5.257775368758134 0.6327915934987465 1.0208269213337593 1.320151630946141 0.548137080847523 0.0676850359873119 1.5510322562707632 0.7029441045350542 0.03433509153416149 0.30969361591507566 5.52363065563127e-06 5.257775368758134 0.29932470961238167 NCASPSS(ph)AGQLILPECMK ddPTM_PC-9_Lapatinib_30min_R1 2 NCASPSSAGQLILPECMK 18 0 G5EA31;P53992;P53992-2 G5EA31 SEC24C Protein transport protein Sec24C 1 NCAS(0.055)PS(0.022)S(0.923)AGQLILPECMK;NCASPS(0.075)S(0.924)AGQLILPECMK 127.49 3.795e-05 9283400.0 45157.0 54532.0 67527.0 62791.0 74171.0 66751.0 62503.0 73429.0 67998.0 54221.0 True False 44513.05289922041 54405.73450443609 61975.19072175795 67408.85960463561 69808.40760579654 63896.21533418102 65739.09951047228 76840.77940574347 60339.349189316075 63593.0276050589 0.6999675054892236 0.8555298678704212 0.9745595241455016 1.060003936646557 1.0977368154153302 1.0047676253284408 1.0337469685944416 1.2083208222599342 0.9488359252849287 1.0 15.956580975388869 -4.976331188034474 1.3021411262168556 1.0600362509817267 0.6163692217917026 0.7416180185988013 0.06637528064705232 0.4585448961442863 0.880099738748717 0.019444050918250706 0.24770451108591127 1.0560118994094032e-05 4.976331188034474 -0.4436670291900241 NCDLDVACR ddPTM_PC-9_Lapatinib_30min_R1 2 NCDLDVACR 9 0 P30838;A8MYB8;I3L3I9;C9JMC5;E9PNN6;C9JKT2 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 0 ; 145.46 0.0022663 25714000.0 106627.0 183688.0 157655.0 166000.0 170230.0 170721.0 171122.0 182983.0 153401.0 174155.0 False True 105106.47942700317 183262.681721757 144693.2144658987 178208.19375976696 160217.40608505707 163419.6608000885 179981.8598536233 191485.0581922833 136123.36399585687 204257.45970304956 0.5145784128511509 0.8972141433080835 0.7083864387438009 0.8724684719904323 0.7843894970493703 0.8000670381276098 0.8811519545738097 0.9374691062478949 0.6664303188424728 1.0 17.640029242551087 -4.754209282182786 24.99877569889469 0.8320832355716576 0.5145778586921643 0.5013140244168346 0.09675975856551951 206.7948863506744 714952.8012195994 0.022335510618525917 0.22293048014865247 1.76112717226259e-05 4.754209282182786 -0.3175053768794933 NCDLDVACRR ddPTM_PC-9_AZD4547_30min_R2 1 NCDLDVACRR 10 1 P30838;A8MYB8;I3L3I9;C9JMC5;E9PNN6;C9JKT2 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 0 70.41199999999999 0.022681 6517100.0 31091.0 24465.0 41195.0 62476.0 56558.0 42476.0 36677.0 41622.0 31692.0 41458.0 False True 40977.29126702588 32372.832810849577 40648.72738366515 48073.12344457794 48705.89796214341 39819.96900526743 39941.181947236284 35190.276278410085 33367.17441949969 40006.56803883307 1.0242640965166159 0.8091879508241328 1.0160513479738815 1.2016307771742611 1.2174475429850964 0.9953357900286642 0.9983656160775071 0.8796124737381129 0.8340424099140737 1.0 15.287949252028957 -7.571023824238457 2.64637794191557 0.8925418979466259 1.0463123877828395 0.2274258427085074 0.11365343429841937 0.4540964495387048 6.412119224785303 0.07075573923090935 0.0373038093971541 2.685197138855573e-08 7.571023824238457 0.15377048983621366 NCDLDVACRR ddPTM_PC-9_Lapatinib_30min_R1 1 NCDLDVACRR 10 1 P30838;A8MYB8;I3L3I9;C9JMC5;E9PNN6;C9JKT2 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 0 97.47200000000001 0.0032475 6376800.0 52692.0 41631.0 42501.0 39780.0 37921.0 43731.0 26938.0 31754.0 45962.0 30568.0 False True 51940.60241747065 41534.605977301006 39006.73183860438 42705.553902189844 35690.56133555449 41860.727071940026 28332.7178313537 33229.406763676234 40785.27555868327 35851.638070700275 1.4487651112354352 1.1585134797856038 1.088004173245367 1.1911744121139873 0.9955071303903008 1.1676098868729425 0.7902768006159415 0.926858814599965 1.137612610008328 1.0 15.129751417095504 -1.5228787487271318 0.48679138527369975 0.9879804453187123 13.418171336785171 0.579071350220218 0.10960772866776504 74.90596112741689 0.8248040603620458 0.06334889595004546 945.6317820560907 0.02999999976190389 1.5228787487271318 12.43019089146646 NCGEIFCNACSDNELPLPS(ph)SPKPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NCGEIFCNACSDNELPLPSSPKPVR 25 1 H0YD93;Q8WXA3;Q8WXA3-3;Q8WXA3-1 H0YD93 RUFY2 RUN and FYVE domain-containing protein 2 1 NCGEIFCNACSDNELPLPS(0.5)S(0.5)PKPVR 97.04700000000001 0.00053204 0.0 9144.1 9162.1 5230.0 8273.3 10663.0 11022.0 12492.0 10423.0 8453.2 8817.2 True False 10692.015525792614 10071.652737790548 5354.703034885451 7809.773823400497 8573.661694985967 10443.986916877933 11308.667325751983 10149.407294081366 8576.812058116771 10415.688563083204 1.0265298795212454 0.966969459272041 0.5140997642598846 0.74980869254108 0.8231488146999695 1.0027168970753435 1.0857340114636111 0.9744345976371038 0.823451277961205 1.0 13.34647059614445 -6.722168546019057 6.19863556438827 0.9825492584761031 0.8027217534254758 0.2424200927101109 0.1414795163963362 0.28078928079703674 28.10965246699042 0.05141786511508744 0.05047180500064826 1.8959699684862168e-07 6.722168546019057 -0.17982750505062728 NCGEIFCNACSDNELPLPS(ph)SPKPVR ddPTM_PC-9_Lapatinib_30min_R1 2 NCGEIFCNACSDNELPLPSSPKPVR 25 1 H0YD93;Q8WXA3;Q8WXA3-3;Q8WXA3-1 H0YD93 RUFY2 RUN and FYVE domain-containing protein 2 1 NCGEIFCNACS(0.001)DNELPLPS(0.5)S(0.5)PKPVR;NCGEIFCNACS(0.001)DNELPLPS(0.5)S(0.5)PKPVR 88.976 3.3721e-06 11052100.0 44352.0 48811.0 43241.9 54144.0 52646.0 48275.0 45026.6 43186.3 46998.2 43197.0 True False 43719.53234683934 48697.98112843889 39686.7179005611 58125.93037908919 49549.46578601835 46210.39078452136 47357.857031154155 45192.89315733929 41704.767803013536 50663.54389361553 0.8629386929316001 0.9612036068912989 0.7833387649292 1.1472930220030275 0.9780102609889164 0.9121034028246227 0.9347521588816855 0.8920199749989136 0.8231711522310038 1.0 15.628660376041687 -10.21717046767214 13.660738829041644 0.9999925443656018 0.9262710088693668 0.05637392125191809 0.09447959583218152 0.0 0.0 0.09170958305243562 0.022242841047443968 6.064982224103092e-11 10.21717046767214 -0.07372153549623506 NCGEIFCNACSDNELPLPSS(ph)PKPVR ddPTM_PC-9_AZD4547_30min_R2 1 NCGEIFCNACSDNELPLPSSPKPVR 25 1 H0YD93;Q8WXA3;Q8WXA3-3;Q8WXA3-1 H0YD93 RUFY2 RUN and FYVE domain-containing protein 2 1 NCGEIFCNACS(0.01)DNELPLPS(0.258)S(0.732)PKPVR 50.631 0.010883 6976800.0 16537.0 11053.0 14905.0 19808.0 18540.0 20917.0 18236.0 14102.0 15542.0 18303.0 True False 21795.422009031787 14625.666096804427 14707.349961246002 15241.571630549317 15966.041023694936 19609.056683378363 19858.968672186948 11922.859931722147 16363.518390378142 17662.217540999613 1.2340139033186346 0.828076432806561 0.8327012124669836 0.8629477920973848 0.9039658234665431 1.110226201090521 1.1243757260993972 0.6750488665449514 0.9264702097793339 1.0 14.108378868320552 -12.146638379825733 1.9622695231172473 2.068866943791837 0.9362006226807409 0.008772201562170512 0.15858451249188588 7721719.759919767 448786.94333528803 36724761.26657317 0.04045673735523553 7.13446842390028e-13 12.146638379825733 -1.132666321111096 NCHTASTTTSS(ph)TPPK ddPTM_PC-9_AZD4547_30min_R2 1 NCHTASTTTSSTPPK 15 0 H0Y4A4;A0A2R8Y6E3;P81274 H0Y4A4 GPSM2 G-protein-signaling modulator 2 1 NCHTASTTT(0.02)S(0.221)S(0.379)T(0.379)PPK 108.49 0.00041336 5102100.0 8695.9 7463.6 15180.0 22456.0 17858.0 20253.0 15600.0 21181.0 15565.0 18428.0 True False 11461.015314043627 9876.062741347105 14978.703281564194 17279.11614174151 15378.724951518032 18986.576708345467 16988.369778795586 17907.963140959208 16387.734123422713 17782.841329046667 0.6444985422730558 0.5553703459758957 0.8423121482334678 0.9716735262951277 0.8648069600890085 1.0676908350597836 0.9553237002146905 1.0070360978652024 0.9215475648795689 1.0 14.118198234865977 -5.440815519031831 2.947726487181817 0.9686952778292184 0.5979204318519628 0.8715838946084825 0.05597348174036487 0.08029121051019569 1.3399416363586012 0.015042239020022717 0.03551274726254513 3.6239690581670884e-06 5.440815519031831 -0.37077484597725563 NCHTASTTTSS(ph)TPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NCHTASTTTSSTPPK 15 0 H0Y4A4;A0A2R8Y6E3;P81274 H0Y4A4 GPSM2 G-protein-signaling modulator 2 1 NCHTASTTTS(0.002)S(0.997)T(0.001)PPK 132.5 3.6911e-06 3021200.0 15403.0 17470.0 24273.0 27527.0 31415.0 26625.0 26935.0 22399.0 26296.0 18063.0 True False 18010.423676882772 19204.306144792212 24851.76037586512 25984.751433738118 25259.456264464425 25228.73812936624 24383.52180748717 21811.04998370225 26680.529252855562 21337.67891337067 0.844066674262168 0.9000185176072906 1.1646890215548444 1.2177871613512512 1.1837958742849148 1.1823562549512987 1.1427448086777567 1.0221847499089958 1.2503951044148922 1.0 14.381115629643727 -5.215952990623308 4.616685122536064 1.1519173178754605 0.8611891168556827 0.6780837452369248 0.07548723262201645 0.10965747312153393 5.348258342703275 0.018963250380678677 0.052336801106556655 6.082008312531497e-06 5.215952990623308 -0.2907282010197778 NCHTASTTTSS(ph)TPPK ddPTM_PC-9_Lapatinib_30min_R1 1 NCHTASTTTSSTPPK 15 0 H0Y4A4;A0A2R8Y6E3;P81274 H0Y4A4 GPSM2 G-protein-signaling modulator 2 1 NCHTASTT(0.001)T(0.005)S(0.005)S(0.871)T(0.119)PPK 99.044 0.0012119000000000001 3742600.0 7904.2 8866.0 17590.0 11366.0 12190.0 13702.0 11648.0 12626.0 14624.0 8585.6 True False 7791.484658547249 8845.471321725412 16143.818099363556 12201.8935558645 11473.008166462101 13115.997400922051 12251.076445898285 13212.650053479141 12976.89112245299 10069.6095204071 0.7737623432921606 0.8784324063211343 1.6032218594620224 1.2117543913829139 1.1393697186778562 1.3025328712440272 1.216638681079958 1.3121313221433606 1.2887184052324951 1.0 13.297720119111151 -5.0868702959326635 7.911013106285858 1.2641635594619032 0.7992197178383118 0.5915355421833454 0.14507196264966 0.16384222465042403 13.245148254306926 0.03523507908839953 0.09466750181132037 8.187092629561776e-06 5.0868702959326635 -0.46494384162359137 NCHTASTTTSST(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 1 NCHTASTTTSSTPPK 15 0 H0Y4A4;A0A2R8Y6E3;P81274 H0Y4A4 GPSM2 G-protein-signaling modulator 2 1 NCHTASTTTS(0.009)S(0.44)T(0.55)PPK 137.32 8.497399999999999e-05 3929900.0 7252.9 8261.8 11870.0 10213.0 10884.0 14184.0 8192.1 9066.2 11193.0 6682.4 True False 7149.472315981037 8242.670309703479 10894.094419525047 10964.098089569257 10243.82451876731 13577.383384518938 8616.246853746847 9487.44874979032 9932.326472484701 7837.443936261699 0.9122198990033465 1.0517038943738926 1.390006041270811 1.3989379928883943 1.307036401418063 1.7323739085009742 1.0993695041162388 1.210528435922138 1.2672915498037003 1.0 12.936167502555518 -5.098098666384158 3.7710187528387724 1.319549363711823 0.9348092225945062 0.3240271100255804 0.18684951395050836 0.24930772976644822 6.271683943111627 0.048434018671150846 0.1608595668799828 7.978134132465794e-06 5.098098666384158 -0.3847401411173168 NCIVLIDSTPYR ddPTM_PC-9_AZD4547_30min_R2 1 NCIVLIDSTPYR 12 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 0 145.28 0.00049738 4872900.0 9610.0 10819.0 12908.0 16204.0 10858.0 11447.0 9799.8 12899.0 11090.0 12267.0 False True 12665.78009958248 14316.030172923834 12736.831486062629 12468.41814930438 9350.55412272274 10731.217280424156 10671.963215271862 10905.755939532264 11676.194759316282 11837.536063784211 1.0699676040128148 1.2093758444143063 1.0759698147851666 1.0532950507707672 0.7899071286743404 0.9065414645920505 0.9015358565978687 0.9212859737675784 0.9863703642718743 1.0 13.531081200509288 -6.036059508711942 4.428836115248871 0.9118443138075126 1.121166804120458 0.6699913713945007 0.06437084562273399 0.11734259036999663 5.2807361842542795 0.019101255588212452 0.026318073943580256 9.203234568285048e-07 6.036059508711942 0.20932249031294548 NCIVLIDSTPYR ddPTM_PC-9_Lapatinib_30min_R1 2 NCIVLIDSTPYR 12 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 0 ; 181.68 0.0029822 35223000.0 75709.0 71401.0 83582.0 62314.0 74975.0 71122.0 73433.0 54263.0 65375.0 79461.0 False True 74629.37577666994 71235.67537136449 76710.21059585031 66896.7794334102 70565.11790652135 68080.27785347961 77235.00142957145 56784.257076820715 58011.77907073059 93195.72797487292 0.8007810808322805 0.7643663172046983 0.8231086581193146 0.7178095057259134 0.757171164815053 0.7305085687171751 0.8287397191681926 0.6093010732437293 0.622472513829942 1.0 16.507976203841856 -5.767602087677935 24.895635809093662 0.7384886734020845 0.7929134489025472 0.023806797009585212 0.10455216468934495 456.62458464275375 1844645.0189889665 0.02845466486267216 0.04344753195235787 1.707646264042767e-06 5.767602087677935 0.05442477550046276 NCLTNFHGMDLTR ddPTM_PC-9_Lapatinib_30min_R1 1 NCLTNFHGMDLTR 13 0 D6RAT0;P61247;D6RG13;D6RB09;E9PFI5;D6RAS7;H0Y8L7;D6RED7 D6RAT0 RPS3A 40S ribosomal protein S3a 0 58.817 0.043348000000000005 5200700.0 36807.0 31590.0 25367.0 26490.0 32399.0 29777.0 36650.0 30983.0 34288.0 25828.0 False True 36282.12543042288 31516.8552958838 23281.423179451707 28438.16296804952 30493.354518884797 28503.507123577267 38547.55767017273 32422.58328900237 30426.124371353122 30292.335386353298 1.1977328577567508 1.0404234237444152 0.768558213901857 0.9387907074626184 1.0066359734225727 0.9409478259117025 1.2725185159391315 1.070323000042075 1.0044165952638995 1.0 14.886665186485343 NCNDFQYESK ddPTM_PC-9_Lapatinib_30min_R1 2 NCNDFQYESK 10 0 Q04917;A2IDB2 Q04917 YWHAH 14-3-3 protein eta 0 ; 118.28 0.0023014 0.0 22975.0 21174.0 21750.0 24131.0 20462.3 22102.0 20987.8 19612.0 27632.0 17872.7 False True 22647.372286901 21124.972903926668 19961.798957427953 25905.674238656196 19258.747744429656 21156.748982278452 22074.4455899059 20523.24511712598 24519.793182140376 20961.972381124215 1.0804027347776897 1.0077760107607636 0.9522862922671869 1.2358414450533135 0.9187469286893883 1.0092919023846072 1.0530710177723277 0.9790703252527277 1.169727387114578 1.0 14.355486850746813 -10.67740087204692 4.448692255140872 0.9999929940713433 1.0404331192476661 0.018858202609902897 0.09221591773304282 6.084762074682868e-06 1.156346646582908e-06 0.0847859616975851 0.020560053846814173 2.101837459849863e-11 10.67740087204692 0.04044012517632278 NCPAVTLT(ph)SPAK ddPTM_PC-9_Lapatinib_30min_R1 1 NCPAVTLTSPAK 12 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 NCPAVT(0.001)LT(0.919)S(0.08)PAK 186.51 0.0009103 86913000.0 1085800.0 855350.0 762970.0 1017200.0 961400.0 916520.0 796880.0 745950.0 962710.0 796820.0 True False 1070316.292888668 853369.4896275455 700241.5517493711 1092008.281279725 904852.3421851245 877322.5761124712 838138.5472362137 780609.5602243579 854279.4620142711 934549.2753040912 1.1452753976406431 0.9131348257157111 0.7492826437873176 1.1684865743696593 0.9682232559547985 0.9387654554940411 0.8968371913439165 0.8352791884305478 0.9141085275961492 1.0 19.83391120835126 -6.9731411026527415 3.006426819160466 0.8988004279415197 0.980900482348534 0.08503155057648404 0.1162353795313141 0.6923271312281071 12.821905227916993 0.04680679545117157 0.038562868980119104 1.0637973333971313e-07 6.9731411026527415 0.08210005440701429 NCPAVTLTS(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 2 NCPAVTLTSPAK 12 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 NCPAVTLT(0.08)S(0.92)PAK;NCPAVTLT(0.009)S(0.991)PAK 148.89 9.802299999999999e-05 147382000.0 686660.0 603860.0 687040.0 903260.0 781240.0 726210.0 745240.0 780250.0 702720.0 761450.0 True False 905003.5965847331 799045.9358740897 677929.4006960384 695027.3622278867 672778.311184005 680799.9738985617 811564.9162788213 659680.2908613113 739864.3445686873 734791.8672673405 1.2316461802311487 1.0874452637121683 0.9226141862691387 0.9458833081708752 0.9156039160940073 0.9265208343015929 1.1044827146726548 0.8977784325711633 1.006903284490901 1.0 19.486976133115242 -4.943480460453741 2.790604442123276 0.962845855830994 1.2409603575189536 0.6747000754697794 0.0581668481330062 0.18076789533452162 2.452993789214388 0.015088084117659516 0.09819277515589886 1.1389890255111604e-05 4.943480460453741 0.2781145016879596 NCPAVTLTS(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NCPAVTLTSPAK 12 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 NCPAVTLT(0.052)S(0.948)PAK;NCPAVTLT(0.039)S(0.961)PAK 138.02 6.8159e-05 136048000.0 889660.0 837720.0 771760.0 1104980.0 1169790.0 1088110.0 1088470.0 1165580.0 1000390.0 910780.0 True False 1040261.8664140454 920883.3053013915 790161.6853160984 1043071.5529934934 940578.0469077769 1031047.5960918191 985362.2417596254 1134984.7600340943 1015018.8111980616 1075897.204269488 0.9668784920027389 0.8559212735631674 0.7344211716328437 0.969489974371406 0.8742266855748638 0.9583142255601259 0.9158516611525781 1.0549193320050734 0.9434161620368168 1.0 20.037108812669317 -6.95351310350193 0.9901084970418379 0.9954115023803785 0.8659037291517435 0.3236099917190355 0.06948677870349526 0.6189382121276729 1.2662957676497293 0.044141366500993484 0.03322989390676695 1.1129788115783871e-07 6.95351310350193 -0.12950777322863494 NCPAVTLTS(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 1 NCPAVTLTSPAK 12 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 NCPAVTLT(0.023)S(0.977)PAK 170.0 0.0010382999999999998 93581000.0 1062100.0 911050.0 907890.0 860800.0 982750.0 869970.0 886070.0 877710.0 995670.0 779240.0 True False 1046954.2592347149 908940.5196997455 833246.7887567473 924106.1035446211 924946.5771608388 832763.4110991217 931946.3690261927 918491.6108378876 883527.159730085 913930.5957279671 1.1455511656230213 0.9945399836141311 0.9117177963530663 1.0111337861586185 1.0120534113688329 0.911188896609601 1.0197124085597284 1.0049905486600845 0.9667333207357338 1.0 19.801725085014567 -4.767920620065457 5.0212117108473455 0.9794529380805559 1.1551642685751156 0.6327172620661838 0.03766978673477839 0.10438537313719842 6.975641625329748 0.009307953920122042 0.06421112060661419 1.7063942536284588e-05 4.767920620065457 0.17571133049455967 NCPHIVVGT(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NCPHIVVGTPGR 12 0 A0A140T9L4;A0A140T973;A0A140T9K1;A0A140T9X9;A0A140T996;F6S4E6;A0A0A0MT12;F6TRA5;F6UJC5;A0A140TA18;F6WLT2;A0A140T9X3;A0A0G2JJZ9;Q5STU3;Q13838;Q13838-2 A0A140T9L4 DDX39B Spliceosome RNA helicase DDX39B 1 NCPHIVVGT(1)PGR 79.317 0.032537 6166500.0 21511.0 21696.0 19759.0 21936.0 22162.0 22924.0 21659.0 25755.0 19082.0 18792.0 True False 25152.387438383746 23849.835496131192 20230.12949642479 20706.99703747155 17819.51519124816 21721.8250846044 19607.302722419332 25078.958539678166 19361.038150402717 22198.840842609854 1.1330495865398822 1.074373011871517 0.9113146780886777 0.9327963196044559 0.8027227780760633 0.9785116816960172 0.8832579530361712 1.1297418057766346 0.87216437505331 1.0 14.438196724850995 -5.128901373562128 3.77167774690642 0.9379065864351738 1.1224236216881882 0.3929481287064278 0.08313135692608527 0.2314012412899336 5.676518815891076 0.02139646156958013 0.06858949574582876 7.431878935578148e-06 5.128901373562128 0.18451703525301444 NCPHIVVGT(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 1 NCPHIVVGTPGR 12 0 A0A140T9L4;A0A140T973;A0A140T9K1;A0A140T9X9;A0A140T996;F6S4E6;A0A0A0MT12;F6TRA5;F6UJC5;A0A140TA18;F6WLT2;A0A140T9X3;A0A0G2JJZ9;Q5STU3;Q13838;Q13838-2 A0A140T9L4 DDX39B Spliceosome RNA helicase DDX39B 1 NCPHIVVGT(1)PGR 99.834 0.0078777 5262200.0 28277.0 22875.0 23373.0 25131.0 29319.0 30254.0 23844.0 23567.0 25721.0 21760.0 True False 27873.764794633305 22822.034342935814 21451.362162389127 26979.21757455842 27594.514063371822 28960.106945518604 25078.525650411968 24662.008855563337 22824.030125862504 25521.18700662257 1.092181362387269 0.8942387490446136 0.8405315221749932 1.0571302019595523 1.0812394445529214 1.134747648610688 0.982655142329558 0.9663347104178076 0.8943169500674019 1.0 14.639407810875696 -4.7053210670579935 22.789905618602845 0.9880069590106124 1.0921884162129176 0.12236018440674312 0.08658210762002881 21186.637054252213 8601337.66134786 0.023958597361570553 34.22855170348126 1.9709650939800482e-05 4.7053210670579935 0.1041814572023052 NCPHVVVGT(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NCPHVVVGTPGR 12 0 K7EQN7;O00148-3;O00148-2;O00148;A0A0D9SEM9;K7EPJ3 K7EQN7 DDX39A ATP-dependent RNA helicase DDX39A 1 NCPHVVVGT(1)PGR 77.324 0.037094999999999996 5811400.0 17716.0 18042.0 23111.0 24765.0 29747.0 20853.0 28632.0 24181.0 20002.0 24459.0 True False 20714.96889305038 19833.090524575917 23662.05388895557 23377.49733921328 23918.288890626252 19759.43197039152 25919.769682271115 23546.274371887303 20294.49140993372 28893.22308266252 0.7169490518169456 0.6864270721142507 0.8189482295297843 0.809099672692488 0.827816572149007 0.6838777354073813 0.8970882067436902 0.8149410782079319 0.702396245371168 1.0 14.81844352723913 -14.522878745279645 0.22704123412047303 2.1497278526747023 0.7519960426101835 0.48424328623060353 0.06943993669178189 143.22713816739775 1.4301007073222034 75.83189419961863 0.12565021213639027 3.0000000000047866e-15 14.522878745279645 -1.3977318100645189 NCPPS(ph)PLPLISK ddPTM_PC-9_AZD4547_30min_R2 2 NCPPSPLPLISK 12 0 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1;Q8IWC1-3 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 1 NCPPS(0.94)PLPLIS(0.06)K;NCPPS(1)PLPLISK 121.95 0.00042302 62274000.0 180584.0 151741.0 194813.0 270690.0 221600.0 174497.0 188683.0 257300.0 208808.0 215835.0 True False 238005.9556194592 200788.31079301573 192229.65233144688 208286.60261881063 190834.6650944333 163585.67500499502 205475.4214725954 217540.19716579944 219845.16459001912 208278.68234506078 1.1427283528957057 0.9640367825083723 0.9229444423552429 1.0000380272894982 0.9162467466462674 0.7854172744091895 0.9865408171354707 1.0444669359171135 1.0555336826348645 1.0 17.668155659235843 -10.230340149660199 7.606523586043496 1.0000007818846908 0.9727514656510072 0.0 0.0909210738677036 0.0 0.0 0.09279515293919957 0.022506130418450884 5.883826397078445e-11 10.230340149660199 -0.02724931623368354 NCPPS(ph)PLPLISK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NCPPSPLPLISK 12 0 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1;Q8IWC1-3 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 1 NCPPS(0.976)PLPLIS(0.024)K 104.94 0.0018506 11838000.0 37544.0 48377.0 43324.0 65250.0 93252.0 90226.0 103200.0 148810.0 117490.0 94570.0 True False 43899.457672199336 53179.5488475451 44357.00846718495 61594.25404335424 74979.94001508314 85494.38972620462 93424.1488967021 144903.89517722794 119208.06898075747 111714.79238429216 0.3929601150865308 0.47602960818841833 0.39705581973960535 0.5513527146116309 0.6711728895951098 0.7652915777895292 0.8362737548249533 1.2970878080206896 1.0670750617401579 1.0 16.769460703109452 -6.971370592216837 0.925653101526901 1.1368290852397993 0.4292318751207383 0.8769163508553028 0.1018377083347207 0.17863304185815354 0.31933428688416843 0.06826180499906943 0.05096066386699328 1.0681430222994327e-07 6.971370592216837 -0.7075972101190611 down NCPPS(ph)PLPLISK ddPTM_PC-9_Lapatinib_30min_R1 2 NCPPSPLPLISK 12 0 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1;Q8IWC1-3 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 1 NCPPS(1)PLPLISK;NCPPS(0.993)PLPLIS(0.007)K 146.84 7.1735e-05 34358000.0 203740.0 193422.0 189542.0 186184.0 344929.0 343716.0 396694.0 326560.0 430797.0 449970.0 True False 200834.6302386596 192974.14324281225 173958.58841327828 199876.5924516164 324640.9543765059 329016.06792113 417232.87428135116 341733.1697658908 382276.1053664778 527746.7149526628 0.38055117075749834 0.36565673982474983 0.32962514684507666 0.37873583442304265 0.6151453816356303 0.6234355583826641 0.7905930296861736 0.6475325380216591 0.7243552532596375 1.0 19.009486167741592 -6.917291663330104 0.2765593326008614 1.013450349619216 0.1628419396393776 0.8807059624320341 0.07227468656067629 0.9191869572653879 0.16443425314130816 0.13129374700430116 0.272032986711187 1.2097853934369257e-07 6.917291663330104 -0.8506084099798383 down NCPS(ph)PVLIDCPHPNCNK ddPTM_PC-9_AZD4547_30min_R2 2 NCPSPVLIDCPHPNCNK 17 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 NCPS(1)PVLIDCPHPNCNK;NCPS(1)PVLIDCPHPNCNK 186.42 1.5801e-08 26557000.0 148679.0 181806.0 177289.0 209668.0 200174.0 214296.0 201848.0 224245.0 205151.0 192437.0 True False 195955.82928468462 240571.2340898962 174938.03202142534 161332.28193830844 172383.29535475257 200896.03724345076 219812.0809686111 189593.0878874653 215994.86303593282 185699.83920326392 1.0552288581693097 1.295484342485461 0.9420472994052576 0.868779868795238 0.9282899548774768 1.081832047380253 1.1836955912923999 1.0209652776270846 1.1631397418686424 1.0 17.502613040486914 -9.516810317399555 15.678675918195907 0.9999999207728186 1.0570436272813688 0.02044390971233756 0.12301032192418704 0.0 0.0 0.1278816200102531 0.031015848639845574 3.042213453699278e-10 9.516810317399555 0.057043706508550174 NCPS(ph)PVLIDCPHPNCNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NCPSPVLIDCPHPNCNK 17 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 NCPS(1)PVLIDCPHPNCNK;NCPS(1)PVLIDCPHPNCNK 129.29 1.7292e-05 16433700.0 136253.0 174442.0 147957.0 139212.0 170612.0 134718.0 158320.0 120646.0 120991.0 101184.0 True False 159317.94178058184 191759.44891298507 151484.8560100472 131412.4029713934 137181.80334849 127653.1509225152 143322.78346246004 117479.17033500357 122760.26448251633 119527.85822789681 1.3328938051982793 1.6043075794712935 1.267360247694055 1.099429078038335 1.1476973266511097 1.0679782338199884 1.1990743044119039 0.9828601639545224 1.027043120344853 1.0 16.86698737919717 -5.557891530230564 3.1522360770997957 1.0816724645070295 1.4686532360938198 0.7624120922704936 0.08795967228660755 0.10826068585055129 2.197944824435295 0.023858854328834153 0.04865264025333018 2.767632805484353e-06 5.557891530230564 0.38698077158679034 NCPS(ph)PVLIDCPHPNCNK ddPTM_PC-9_Lapatinib_30min_R1 2 NCPSPVLIDCPHPNCNK 17 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 NCPS(1)PVLIDCPHPNCNK;NCPS(1)PVLIDCPHPNCNK 148.19 4.211e-05 26902000.0 96043.0 163810.0 177439.0 159009.0 165088.0 167134.0 166855.0 183028.0 155744.0 150549.0 True False 94673.40920787108 163430.70800945655 162850.6503543478 170703.05229847398 155377.84841549574 159986.06842838335 175493.9354722147 191532.14905656385 138202.47066297292 176571.19405606732 0.5361769778699524 0.925579672738475 0.9222945522055949 0.966766143317069 0.8799728021670286 0.9060711702361959 0.9938990128621402 1.0847304402084177 0.7827011161236694 1.0 17.429890474375675 -4.760554701630341 5.544782086091366 0.9431040417013774 0.5165624628782337 0.7174469482057535 0.07612880514509772 0.07810429347706191 7.737567323294878 0.018435163342521942 0.12797805798485565 1.7355826435165174e-05 4.760554701630341 -0.4265415788231437 NCPS(ph)PVLIDCPHPNCNKK ddPTM_PC-9_AZD4547_30min_R2 4 NCPSPVLIDCPHPNCNKK 18 1 O15014 O15014 ZNF609 Zinc finger protein 609 1 NCPS(1)PVLIDCPHPNCNKK;NCPS(1)PVLIDCPHPNCNKK;NCPS(1)PVLIDCPHPNCNKK;NCPS(1)PVLIDCPHPNCNKK 93.495 0.0004723 59416400.0 195714.0 185491.0 231546.0 327556.0 286781.0 257267.0 213988.0 252174.0 212313.0 244746.0 True False 257946.98089590832 245447.33827579377 228475.54875053113 252043.02488975262 246966.40835039096 241180.05382046674 233032.5174503148 213206.3026820379 223535.43173441978 236177.51703488445 1.092174158380234 1.0392493805392158 0.9673890708097516 1.067176198878087 1.0456812801275785 1.0211812574219052 0.986683746937245 0.9027375059182555 0.9464721051386217 1.0 17.84951210807067 -7.385215841961023 2.730948296029713 0.943604218451486 1.038153256378845 0.5305481303461814 0.0376392928128554 0.21403082737204554 3.0896395281556805 0.018448184005281806 0.011344599498691921 4.118927597906738e-08 7.385215841961023 0.09454903792735891 NCPS(ph)PVLIDCPHPNCNKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NCPSPVLIDCPHPNCNKK 18 1 O15014 O15014 ZNF609 Zinc finger protein 609 1 NCPS(1)PVLIDCPHPNCNKK;NCPS(1)PVLIDCPHPNCNKK;NCPS(1)PVLIDCPHPNCNKK;NCPS(1)PVLIDCPHPNCNKK 82.189 0.0010211999999999999 48261500.0 271517.0 228906.0 245143.0 311740.0 346439.0 297655.0 304595.0 316243.0 293318.0 241889.0 True False 317479.4653948045 251630.27489294804 250988.13883000464 294274.21847471665 278556.7648831708 282045.4478083196 275741.556523169 307941.95633715624 297607.2208468622 285741.56090772926 1.1110720624128037 0.8806218951614241 0.8783746334718627 1.0298614508154895 0.9748556142769914 0.9870648389836324 0.9650033255477685 1.0776939670900583 1.0415258455978147 1.0 18.124351364945312 -7.747902219566726 24.996004890833937 1.044707428831103 0.9704361381141957 0.1640535970551824 0.06578320721531848 354.1165485199904 653869.698863086 0.031183857765729534 0.01787803172807035 1.7868898438254453e-08 7.747902219566726 -0.07427129071690719 NCPS(ph)PVLIDCPHPNCNKK ddPTM_PC-9_Lapatinib_30min_R1 6 NCPSPVLIDCPHPNCNKK 18 1 O15014 O15014 ZNF609 Zinc finger protein 609 1 NCPS(1)PVLIDCPHPNCNKK;NCPS(1)PVLIDCPHPNCNKK;NCPS(1)PVLIDCPHPNCNKK;NCPS(1)PVLIDCPHPNCNKK;NCPS(1)PVLIDCPHPNCNKK;NCPS(1)PVLIDCPHPNCNKK 125.33 2.0347e-05 94226200.0 268570.0 271356.0 312575.0 280852.0 308518.0 289367.0 248015.0 244210.0 290566.0 231567.0 True False 264740.1425502944 270727.69185406336 286876.29007439234 301506.79297480657 290371.5778097255 276991.447957423 260856.00315328463 255556.8881324363 257839.39728437335 271593.0474063674 0.9747677456344477 0.9968137787010091 1.056272584346232 1.1101417943283398 1.069142161711014 1.0198767995079725 0.9604664244699255 0.9409551922367984 0.9493593438663571 1.0 18.051087022499793 -7.175321179813447 3.487447761147034 0.9571193469793807 1.0435872203159962 0.4879412320287312 0.03795208192743225 0.22435151392043912 5.205492740427555 0.017563252267470478 0.013021159180624638 6.678498306562695e-08 7.175321179813447 0.08646787333661543 NCQHANAERPTVAR ddPTM_PC-9_Lapatinib_30min_R1 1 NCQHANAERPTVAR 14 1 Q9Y5J1;F6VJE8 Q9Y5J1 UTP18 U3 small nucleolar RNA-associated protein 18 homolog 0 50.897 0.044752 527450.0 1156.5 1053.9 2253.7 737.79 2734.7 1174.4 2107.8 1303.5 2902.1 949.7 False True 1140.008097923875 1051.4597593014225 2068.40948553358 792.0495377952905 2573.850322627065 1124.1736496601118 2216.9315704553906 1364.0653686607043 2575.2349375321933 1113.8543796042943 1.0234803748124348 0.9439831440757651 1.8569837524617887 0.7110889469022624 2.3107601583803494 1.0092644696153938 1.9903244185680478 1.2246352787563661 2.3120032426923403 1.0 10.121344918098574 -4.885405014154738 0.7332953655985075 1.6089298898655955 0.5987443426715886 0.12177598756126895 0.5441576018591457 5.0635041025449326 2.2818908469393215 0.2114068976092467 4.1330095726413125 1.3019520382667313e-05 4.885405014154738 -1.0101855471940069 NCS(ph)ASTSQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NCSASTSQER 10 0 H7BZV4;A0A0C4DG62;Q66PJ3-4;Q66PJ3-3;F8WEP2 H7BZV4 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 NCS(0.477)AS(0.213)T(0.097)S(0.213)QER;NCS(0.775)AS(0.054)T(0.095)S(0.076)QER 131.06 0.00019236 247090000.0 29759.7 33039.7 33625.0 40321.0 46444.0 36178.0 35598.2 33022.2 36106.0 30212.0 True False 34797.42942913251 36319.6630642296 34426.747523522645 38061.94509244574 37343.63160104361 34280.761992270905 32226.080787350653 32155.402239913037 36633.98194415889 35689.19644193961 0.9750129702623634 1.0176654754139858 0.964626580470346 1.0664836669653295 1.0463567500544737 0.960536112042758 0.902964594335351 0.9009842037834763 1.0264725910474417 1.0 15.12319979838442 -6.897393042363964 6.566773312127238 0.946988446738024 1.0141392279053683 0.2590212088772149 0.04579728070246151 0.2636675695119675 14.716253730210502 0.016458624143435442 0.014510961464358523 1.2665051427991156e-07 6.897393042363964 0.0671507811673443 NCS(ph)ASTSQER ddPTM_PC-9_Lapatinib_30min_R1 2 NCSASTSQER 10 0 H7BZV4;A0A0C4DG62;Q66PJ3-4;Q66PJ3-3;F8WEP2 H7BZV4 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 NCS(0.418)AS(0.1)T(0.142)S(0.34)QER;NCS(0.807)AS(0.034)T(0.034)S(0.126)QER 106.26 0.0023421999999999996 260370000.0 19171.9 23377.0 23891.0 21628.0 28586.0 25743.0 22222.0 25023.0 24481.0 21351.0 True False 18898.505190304124 23322.871992778608 21926.774201926954 23218.595268892965 26904.62768223837 24642.031899863996 23372.546426918914 26185.659930952657 21723.69198364137 25041.491901580786 0.754687670550137 0.9313691086954093 0.8756177262962032 0.9272049508930118 1.074401948093994 0.9840480749594805 0.9333527937863592 1.045690889099928 0.8675078972539182 1.0 14.612032896088953 -3.767779008698113 0.7556335117244007 0.979519455576729 4.69395067935199e-13 0.5184091392050445 0.061600772394693845 8.720197936848088 1.2041266647541662 0.022943468135484563 10.325834820895647 0.00017069507521212326 3.767779008698113 -0.9795194555762596 NCS(ph)ASTSQGR ddPTM_PC-9_AZD4547_30min_R2 2 NCSASTSQGR 10 0 Q66PJ3;F5GYV5;F8WCT1;Q66PJ3-2;A0A0C4DH18;A0A0A0MTG7;Q66PJ3-6;Q66PJ3-5 Q66PJ3 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 NCS(0.706)AS(0.075)T(0.173)S(0.046)QGR;NCS(0.983)AS(0.004)T(0.01)S(0.002)QGR 110.64 0.0017109000000000002 4506000.0 33226.0 23958.0 18093.8 21826.5 18921.5 17362.0 18132.6 15283.8 29045.0 29305.0 True False 43791.17685626717 31701.954975774963 17853.864389721093 16794.737641063446 16294.576333864285 16276.351395363337 19746.366272499305 12922.039896784492 30580.259403457276 28279.04086974779 1.5485382640085885 1.1210406718457315 0.6313461786754129 0.5938934675479053 0.5762068243020156 0.5755623562458008 0.6982685998245249 0.45694760145165203 1.0813754095942933 1.0 14.787445569147824 -3.1732295926904857 9.522237875955515 0.791790699956596 1.0050381326017397 0.0 0.32974019822701706 0.0 0.0 0.07920962177930498 0.0 0.0006710739913681025 3.1732295926904857 0.21324743264514368 NCS(ph)ASTSQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NCSASTSQGR 10 0 Q66PJ3;F5GYV5;F8WCT1;Q66PJ3-2;A0A0C4DH18;A0A0A0MTG7;Q66PJ3-6;Q66PJ3-5 Q66PJ3 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 NCS(0.916)AS(0.001)T(0.025)S(0.058)QGR 101.56 0.0035567 2216900.0 6780.2 12008.0 11680.0 7124.0 19300.0 17711.0 8900.4 11464.0 14843.0 14607.0 True False 7927.953944945825 13200.074881892675 11958.495496646667 6724.865376319621 15518.303546209245 16782.20398156641 8057.289678684201 11163.082147112043 15060.050794802823 17255.133471051624 0.4594548027255944 0.7649940757652215 0.6930398722623065 0.38973128707475424 0.8993441616805687 0.9725919541405674 0.4669502958178593 0.646942671631024 0.8727866880930583 1.0 14.074738012829082 -14.522878739824067 0.10943892667288872 2.012486111706011 0.5045189594403798 0.26863374290360487 0.18074438294165168 264.5473314881035 1.9202368304777133 59.96660441706388 2.4093091554029713 3.00000003769058e-15 14.522878739824067 -1.5079671522656313 NCS(ph)ASTSQGR ddPTM_PC-9_Lapatinib_30min_R1 2 NCSASTSQGR 10 0 Q66PJ3;F5GYV5;F8WCT1;Q66PJ3-2;A0A0C4DH18;A0A0A0MTG7;Q66PJ3-6;Q66PJ3-5 Q66PJ3 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 NCS(0.598)AS(0.017)T(0.297)S(0.088)QGR;NCS(0.997)AS(0.003)TSQGR 140.45 0.00012306 6636900.0 10789.0 23795.0 16166.9 18844.9 23516.0 15665.3 44018.0 42540.0 23783.0 24029.0 True False 10635.146881539717 23739.904139460457 14837.719888038711 20230.816810743527 22132.83511423484 14995.331636597888 46297.036658271885 44516.56369990513 21104.308093907235 28182.3806333701 0.3773686481597969 0.8423668833480515 0.5264892303125632 0.7178533663969001 0.7853429915011462 0.5320817936452915 1.6427652887298188 1.5795884768937547 0.7488475997985109 1.0 14.78250586425916 -7.247947593248411 24.88241122716435 1.291099388966361 0.6462073045352204 0.5431610109608389 0.27354572409114725 532.3136939800105 981728.095706866 0.10284326778191165 0.07920412974976915 5.6500515043813175e-08 7.247947593248411 -0.6448920844311405 NCS(ph)SPEFSK ddPTM_PC-9_AZD4547_30min_R2 2 NCSSPEFSK 9 0 Q5JX53;Q5JX54;F2Z2V0;A6PVH9;E7ENH5;Q5JX45;Q5JX52;Q5JX44;Q5JX60;Q5JX61;Q5JX59;Q5JX58;Q5JX56;Q5JX55;E7EV27;Q5JX57;B0QZ18;Q99829 Q5JX53 CPNE1 Copine-1 1 NCS(0.967)S(0.033)PEFSK;NCS(0.912)S(0.088)PEFSK 136.81 0.00098076 17767400.0 145513.0 110670.0 157798.0 223900.0 181761.0 163391.0 171377.0 203661.0 159074.0 180091.0 True False 191783.10714157554 146441.91323019506 155705.49541661842 172283.3142205168 156526.62257323723 153174.13494066446 186629.2209987595 172189.87211420102 167482.32688399267 173786.0689054342 1.1035585783687556 0.8426562275822093 0.8959607429830619 0.9913528472426917 0.9006856738235519 0.8813947855855712 1.0739020807261248 0.9908151625657535 0.9637270003220356 1.0 17.406952911441905 -7.252908461822879 24.955504223452504 1.0063456590070343 0.9307946413217543 0.18600250080654346 0.07246036142157929 1010.4759537497478 2955950.508779059 0.027366388281798732 0.020868537628617553 5.5858791838667624e-08 7.252908461822879 -0.07555101768528005 NCS(ph)SPEFSK ddPTM_PC-9_Lapatinib_30min_R1 1 NCSSPEFSK 9 0 Q5JX53;Q5JX54;F2Z2V0;A6PVH9;E7ENH5;Q5JX45;Q5JX52;Q5JX44;Q5JX60;Q5JX61;Q5JX59;Q5JX58;Q5JX56;Q5JX55;E7EV27;Q5JX57;B0QZ18;Q99829 Q5JX53 CPNE1 Copine-1 1 NCS(0.734)S(0.266)PEFSK 149.49 0.00026763 10115000.0 81269.0 91301.0 101640.0 89719.0 91140.0 94167.0 79007.0 78506.0 98642.0 76522.0 True False 80110.08915709074 91089.59814401658 93283.55154174598 96317.23455381033 85779.32438813431 90139.69692399853 83097.59587577994 82153.67536024349 87531.89921369027 89748.72574084418 0.8926041957232275 1.014940294607015 1.0393858048871787 1.073187766831734 0.9557720589351675 1.004356286731951 0.9258916512723551 0.9153742817192532 0.9752996322916588 1.0 16.45360383513789 -7.248867897184389 23.84797497566052 0.9470892485742967 1.0010920572738695 0.1354922449501843 0.05073529478114372 686.1634941114011 1301647.175386091 0.019937492058581762 0.015321988224837655 5.638091280638731e-08 7.248867897184389 0.05400280869957286 NCSAST(ph)SQASPSPCITER ddPTM_PC-9_AZD4547_30min_R2 1 NCSASTSQASPSPCITER 18 0 F5H7X4;Q66PJ3-7 F5H7X4 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 NCSAS(0.049)T(0.513)S(0.053)QAS(0.304)PS(0.081)PCITER 239.43 3.0615999999999997e-43 8294200.0 12027.0 12322.0 12257.0 22049.0 15765.0 15172.0 12254.0 13573.0 13069.0 14409.0 True False 15851.335822859359 16304.845530156887 12094.464171418465 16965.943703654182 13576.301873708242 14223.292441565072 13344.582260856498 11475.604726511468 13759.800659107701 13904.54529575826 1.140011088869982 1.1726270211173944 0.8698209049028032 1.2201724934385187 0.9763930847742175 1.0229239532129144 0.9597280584879978 0.825313196686283 0.9895901208150464 1.0 13.763268946220334 -6.820615684443695 1.3617738390725034 0.9294647697734904 1.0895302124015311 0.28945790222209966 0.10151565494667382 0.5224789335311073 2.021035549330118 0.048323092795505805 0.041411144996442766 1.511417044626079e-07 6.820615684443695 0.1600654426280408 NCSASTS(ph)QER ddPTM_PC-9_AZD4547_30min_R2 2 NCSASTSQER 10 0 H7BZV4;A0A0C4DG62;Q66PJ3-4;Q66PJ3-3;F8WEP2 H7BZV4 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 NCS(0.027)AS(0.116)T(0.258)S(0.599)QER;NCSAS(0.001)T(0.004)S(0.995)QER 113.38 0.0013155999999999999 141448900.0 25898.0 27569.0 32398.0 45996.0 45620.0 37100.0 30788.0 35010.0 33259.0 35137.0 True False 34133.025288135985 36480.14010882124 31968.38135152287 35392.332831116044 39286.450458520136 34780.131135121526 33528.07235574095 29600.008949765455 35017.00284040578 33906.86432487045 1.0066700642412294 1.0758924729605064 0.9428291877781894 1.04381025894972 1.158657730249146 1.0257548678605042 0.9888284576981171 0.8729798387182048 1.032740819230549 1.0 15.04928975099235 -7.306830301302809 3.780763383870885 0.9603183574524311 1.0451787633474225 0.21526014063521404 0.06385735135976911 0.3306170500272696 9.967859550219938 0.028433428017793288 0.019085701733273296 4.9336654714780885e-08 7.306830301302809 0.08486040589499144 NCSASTS(ph)QER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NCSASTSQER 10 0 H7BZV4;A0A0C4DG62;Q66PJ3-4;Q66PJ3-3;F8WEP2 H7BZV4 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 NCS(0.037)AS(0.218)T(0.11)S(0.636)QER;NCS(0.001)AS(0.029)T(0.015)S(0.955)QER 108.56 0.0020097 6321600.0 33219.0 35759.0 37167.0 41737.0 40606.0 38079.0 42266.0 36877.0 38164.0 33324.0 True False 38842.32059484313 39308.917197002 38053.202236632416 39398.61120317967 32649.54579260998 36082.07020575164 38262.258500659096 35909.01782441125 38722.076300805435 39365.37740736115 0.9867127702827456 0.9985657393862916 0.9666667702140876 1.0008442392276495 0.8293975046840186 0.9165940372517413 0.9719774334871288 0.9121979818157776 0.983658200456236 1.0 15.2646396893788 NCSASTS(ph)QER ddPTM_PC-9_Lapatinib_30min_R1 1 NCSASTSQER 10 0 H7BZV4;A0A0C4DG62;Q66PJ3-4;Q66PJ3-3;F8WEP2 H7BZV4 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 NCS(0.001)AS(0.015)T(0.046)S(0.938)QER 84.352 0.012598999999999999 1486900.0 8438.7 10791.0 10131.0 9442.1 10811.0 8068.3 9198.0 9839.4 9553.4 8728.0 True False 8318.362590531951 10766.01410249706 9298.06828679092 10136.503531922242 10175.118235243785 7723.237617125923 9674.22743384035 10296.574444495694 8477.395490238127 10236.623170671028 0.8126080692669152 1.0517153872912692 0.9083140144721588 0.9902194662165901 0.9939916772941823 0.754471224383231 0.9450604239841514 1.0058565478893893 0.8281437490564986 1.0 13.3214522610616 -3.2450112058461604 15.014074670144886 0.9311328853333832 0.3375673727627734 0.0 0.09428033232785953 0.0 0.0 0.020639351307405563 0.0 0.0005688382532541902 3.2450112058461604 -0.5935655125706099 NCSASTSQAS(ph)PSPCITER ddPTM_PC-9_AZD4547_30min_R2 3 NCSASTSQASPSPCITER 18 0 F5H7X4;Q66PJ3-7 F5H7X4 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 NCSAS(0.003)T(0.019)S(0.019)QAS(0.959)PS(0.001)PCITER;NCS(0.015)AST(0.008)S(0.008)QAS(0.959)PS(0.01)PCITER;NCS(0.003)AS(0.024)T(0.003)S(0.001)QAS(0.962)PS(0.008)PCITER 241.92 2.9542999999999996e-44 18557000.0 36964.5 37858.6 48832.0 61283.0 60599.0 52891.0 40375.9 48042.8 42825.9 52436.0 True False 48718.442090636454 50095.652084726345 48184.45577373802 47155.151162911665 52185.87486488077 49583.717408833254 43969.27688151753 40618.88917371586 45089.58964319232 50600.23160027622 0.9628106542178456 0.990028118457325 0.9522576132531967 0.9319157180034379 1.0313366799806483 0.9799108786799027 0.8689540638639588 0.8027411711193457 0.8910945309378026 1.0 15.626856367785345 -7.261298445850311 24.999726704300993 0.8742592014310205 0.9750144168629149 0.36843940054047297 0.052137353366034714 11.415731757852422 2025214.2869123193 0.02024952305463509 0.014673681390026488 5.479003200834533e-08 7.261298445850311 0.10075521543189436 NCSASTSQAS(ph)PSPCITER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NCSASTSQASPSPCITER 18 0 F5H7X4;Q66PJ3-7 F5H7X4 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 NCSAST(0.001)S(0.011)QAS(0.755)PS(0.233)PCITER;NCSAS(0.166)T(0.235)S(0.008)QAS(0.468)PS(0.123)PCITER 251.0 4.5805e-54 9316000.0 11879.9 11730.7 13437.7 17064.8 17552.2 17991.1 16163.8 15490.0 15416.1 13183.0 True False 13890.932431279583 12895.246370504528 13758.105730761043 16108.714580828066 14112.97240952197 17047.61504447854 14632.647848222052 15083.40391301164 15641.53129810415 15572.973543429422 0.8919897277511571 0.8280529299393381 0.8834604189362338 1.0344019744144937 0.9062477612361026 1.0946923525514691 0.9396181023113525 0.968562867646793 1.0044023547900816 1.0 13.926756822153273 -5.650951860325015 5.7427883458587115 0.989417654212631 0.8594127948742664 0.5633170388114799 0.050450090784784185 0.14152709922213905 6.578185178599645 0.013035421468114726 0.02282610155789341 2.2338198184248097e-06 5.650951860325015 -0.1300048593383646 NCSASTSQAS(ph)PSPCITER ddPTM_PC-9_Lapatinib_30min_R1 2 NCSASTSQASPSPCITER 18 0 F5H7X4;Q66PJ3-7 F5H7X4 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 NCSASTS(0.068)QAS(0.824)PS(0.107)PCITER;NCSAS(0.062)T(0.011)S(0.011)QAS(0.912)PS(0.004)PCITER 214.52 2.0821e-27 8928500.0 14821.1 18826.1 20269.6 19118.3 23244.0 18839.8 16745.6 16389.8 18371.3 14731.4 True False 14609.74839614313 18782.509322122132 18603.111730918692 20524.323558779197 21876.833619462283 18034.065671718814 17612.60523114992 17151.329941906562 16302.130735634608 17277.702861643356 0.8455839594612368 1.087095285324038 1.0767120999758455 1.1879081219959724 1.2661887864751415 1.0437768154790177 1.0193835009311365 0.9926857800050872 0.9435357736024893 1.0 14.076623797837005 -7.237197470967712 2.962381959220929 0.9838090970603596 1.0997763005875467 0.1784647685711097 0.1023812991036058 0.47034109287628373 8.327080659226894 0.04824655822129032 0.03352791851559781 5.7916529373353125e-08 7.237197470967712 0.11596720352718715 NCSASTSQASPS(ph)PCITER ddPTM_PC-9_Lapatinib_30min_R1 2 NCSASTSQASPSPCITER 18 0 F5H7X4;Q66PJ3-7 F5H7X4 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 NCSAS(0.002)T(0.004)S(0.006)QAS(0.044)PS(0.9)PCIT(0.043)ER;NCSASTS(0.012)QAS(0.122)PS(0.865)PCIT(0.001)ER 121.26 7.0003e-05 15152800.0 15365.0 14483.099999999999 14337.1 11017.8 19615.1 12760.400000000001 14779.0 16222.1 18985.0 15528.7 True False 15145.8922824041 14449.565271789012 13158.358980806448 11828.085766303351 18461.378382770374 12214.667437945245 15544.184305797631 16975.83798768761 16846.709379087104 18212.815104307894 0.8316063275040676 0.7933735223815698 0.722478041173003 0.6494375360734674 1.0136477132743573 0.67066334160808 0.8534751062245699 0.9320820471994085 0.9249920609528582 1.0 14.15266631247011 -7.6384897007981305 3.249967251144203 0.9491511167652841 0.7814430027381432 0.3859752689227308 0.09682292422933199 0.271190010475908 5.639832724174262 0.051423021931220655 0.026878226088272356 2.298848225317497e-08 7.6384897007981305 -0.16770811402714092 NCSEEKS(ph)PQTSILK ddPTM_PC-9_Lapatinib_30min_R1 1 NCSEEKSPQTSILK 14 1 Q8ND24 Q8ND24 RNF214 RING finger protein 214 1 NCSEEKS(0.806)PQT(0.171)S(0.022)ILK 74.726 0.0086435 5931000.0 21454.0 19747.0 17738.0 20642.0 19507.0 17382.0 19590.0 16587.0 17803.0 14368.0 True False 21148.06202581825 19701.277034752056 16279.650110660083 22160.0815396934 18359.6366122376 16638.61237942104 20604.274345393835 17357.692573820565 15797.838666098904 16851.489655843416 1.2549669173303593 1.1691118967586613 0.9660659350085977 1.3150221133126458 1.0894963583157895 0.9873674505476993 1.2226975042677668 1.0300390605409544 0.9374743116921329 1.0 14.04058850947914 -7.563211765829335 0.5487118786396463 0.969477953502526 1.1685315976194914 0.27466267851390114 0.10841535613133334 1.2373816110553542 0.7942959919203623 0.1064257374459702 0.0725342709925376 2.733935310210137e-08 7.563211765829335 0.19905364411696547 NCSETQYESK ddPTM_PC-9_AZD4547_30min_R2 1 NCSETQYESK 10 0 P61981 P61981 YWHAG 14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed 0 115.57 0.0051269 2390700.0 5879.4 5456.5 9071.5 11993.0 11584.0 7711.2 8205.4 9655.1 7394.3 8414.7 False True 7748.926900882955 7220.206917326822 8951.205982787194 9228.19914000293 9975.761554394943 7229.017444990542 8935.66470403394 8163.126147125976 7785.147602237362 8120.1039142353475 0.9542891301302583 0.8891766649277829 1.102351161676003 1.1364631829187533 1.2285263415048722 0.8902616913950272 1.1004372355837506 1.005298236739952 0.9587497505529733 1.0 12.987282474583962 -10.534625583696775 14.706229491283699 0.9999887407216849 1.033799255901838 0.005490117714166742 0.1057751514852604 0.0 0.0 0.10707347765984225 0.025969132829043683 2.919943286443196e-11 10.534625583696775 0.03381051518015321 NCSETQYESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NCSETQYESK 10 0 P61981 P61981 YWHAG 14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed 0 136.49 1.7864e-05 0.0 7192.1 7157.7 8740.8 11221.0 13365.0 9547.2 9088.8 8361.4 11340.0 7940.5 False True 8409.580479549995 7868.26915240866 8949.213821668594 10592.323748972844 10746.224191455261 9046.52802511495 8227.84306678632 8141.9221096356105 11505.826046827731 9380.049793036584 0.8965390019350398 0.8388302115677237 0.954068903590701 1.1292396077509321 1.1456468172943897 0.964443497072987 0.8771641140854475 0.8680041459566542 1.2266273954504217 1.0 13.195379865822385 -5.520117067813435 24.126757040588323 1.0219978464896258 0.8748758060624185 0.2606953415218465 0.10904997607442711 100.33349742341261 876537.2433772073 0.03141900931747873 0.05580701763349441 3.0191377761456688e-06 5.520117067813435 -0.14712204042720722 NCSETQYESK ddPTM_PC-9_Lapatinib_30min_R1 2 NCSETQYESK 10 0 P61981 P61981 YWHAG 14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed 0 ; 121.29 0.0029256 13186400.0 31177.0 34956.0 37492.0 32923.0 28178.0 28421.0 27213.0 27352.0 36413.0 29484.0 False True 30732.410262838443 34875.06152969026 34409.552483305226 35344.26724790841 26520.625440079493 27205.500082586892 28621.95598576836 28622.87377338518 32311.784494111078 34580.270115039486 0.8887267265582304 1.008524844186297 0.9950631492707741 1.0220934402862472 0.7669293892688615 0.7867347476489146 0.8276961368592732 0.8277226776472362 0.934399424487381 1.0 15.077661517821314 -6.252036558526494 24.989286219780524 0.8436300335968369 0.981915180134639 0.389898642255348 0.07314162778454117 612.4814167540884 1627752.5485411254 0.021367981632123167 0.02720408248989101 5.597104835770518e-07 6.252036558526494 0.1382851465378021 NCSS(ph)PEFSK ddPTM_PC-9_Lapatinib_30min_R1 1 NCSSPEFSK 9 0 Q5JX53;Q5JX54;F2Z2V0;A6PVH9;E7ENH5;Q5JX45;Q5JX52;Q5JX44;Q5JX60;Q5JX61;Q5JX59;Q5JX58;Q5JX56;Q5JX55;E7EV27;Q5JX57;B0QZ18;Q99829 Q5JX53 CPNE1 Copine-1 1 NCS(0.036)S(0.964)PEFSK 136.96 0.00097226 9886800.0 87289.0 84623.0 100120.0 88253.0 102670.0 92140.0 79969.0 79787.0 104350.0 82010.0 True False 86044.24285315782 84427.06064272148 91888.52007437655 94743.42002337742 96631.15245698649 88199.38698883068 84109.40352867793 83494.19529676362 92597.0041457856 96185.31922854415 0.8945673159196955 0.8777541242246741 0.9553279108638393 0.9850091550692819 1.0046351483991336 0.9169734809452756 0.8744515712301909 0.8680554991804375 0.9626937342253612 1.0 16.553529091710708 -5.536049094098902 0.005467401878153167 1.846566771618307 6.894621933500867e-08 0.10055342476362439 0.048478090686610624 65814.64535742524 73.33409971431809 12011.782743908872 12761.517719109044 2.9103880994779814e-06 5.536049094098902 -1.8465667026720876 NCSSFLIK ddPTM_PC-9_Lapatinib_30min_R1 1 NCSSFLIK 8 0 P46779;H0YKD8;P46779-2;P46779-3;H0YLP6;H0YMF4;P46779-4;P46779-5 P46779 RPL28 60S ribosomal protein L28 0 105.78 0.017677000000000002 5209700.0 27437.0 28524.0 31827.0 27861.0 26998.0 29893.0 24240.0 25184.0 22434.0 26831.0 False True 27045.74334867044 28457.954430509344 29210.306915772842 29909.990881571426 25410.030720110248 28614.546073986483 25495.028592769093 26354.14057871207 19907.246679507003 31468.702599939774 0.8594489481343346 0.9043256340210164 0.9282335940925873 0.9504678747584805 0.8074699183867491 0.9093017414083429 0.810170947207016 0.8374714685175012 0.6326046209335972 1.0 14.941630079596115 -7.120619287107459 1.3386443736519051 0.8024787930400059 0.9020904908835761 0.11407772318118148 0.0913232884656827 0.7792440780948682 2.7852484780835134 0.050219856831006396 0.03296744059550836 7.574966436593226e-08 7.120619287107459 0.09961169784357016 NCVAIAADRR ddPTM_PC-9_AZD4547_30min_R2 4 NCVAIAADRR 10 1 A0A087WXQ8;A0A087WY10;P49720;A0A087WUL2 A0A087WXQ8 PSMB3 Proteasome subunit beta type-3 0 ;;; 91.70100000000001 0.005000999999999999 10348300.0 55625.7 52441.4 57160.6 87153.0 71265.0 70395.7 71063.0 79568.0 67060.0 73010.0 False True 73313.51551356344 69392.05700252956 56402.613095927445 67061.22235042744 61371.084873442356 65993.84575063805 77387.46933272782 67272.59389074375 70604.65469429664 70453.9421225145 1.0405878408631322 0.984927953099652 0.8005600736697915 0.9518448553781794 0.871080922153686 0.9366948642260406 1.098412196696622 0.9548449932547619 1.0021391644987026 1.0 16.1043928117265 -7.032553265017536 24.25245577410355 1.0111529658870306 0.9246056708965776 0.25800927312593847 0.06861138533661412 645.599775317109 480974.95700059726 0.0267459691087262 0.020736979907520842 9.277836930440644e-08 7.032553265017536 -0.086547294990453 NCVAIAADRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NCVAIAADRR 10 1 A0A087WXQ8;A0A087WY10;P49720;A0A087WUL2 A0A087WXQ8 PSMB3 Proteasome subunit beta type-3 0 ;; 120.63 0.00043655 5185100.0 32817.8 34158.0 38655.0 42428.0 50012.0 41588.0 48231.0 45968.0 34923.0 29213.1 False True 38373.205358904335 37548.9804976424 39576.68179990386 40050.89671343193 40212.50761414594 39407.05206851019 43662.210517798936 44761.38870712198 35433.68280717501 34509.203779227624 1.1119701748089186 1.0880859708575639 1.146844246337742 1.160585940193151 1.1652690647806645 1.1419287538656793 1.2652337850831796 1.2970855251683764 1.0267893468032974 1.0 15.074693566825877 -5.4515543499782915 2.790020525912158 1.1683328663715744 1.099659884824465 0.024405675937122395 0.0868792044454369 0.7049269267842835 10.628809270331729 0.023749619503194232 0.056656103609538905 3.535457736868839e-06 5.4515543499782915 -0.06867298154710944 NCVAIAADRR ddPTM_PC-9_Lapatinib_30min_R1 4 NCVAIAADRR 10 1 A0A087WXQ8;A0A087WY10;P49720;A0A087WUL2 A0A087WXQ8 PSMB3 Proteasome subunit beta type-3 0 ;;; 95.48299999999999 0.010757 8261500.0 74518.0 77935.0 79561.0 77928.0 81584.0 78225.0 70555.0 74338.0 81731.0 68995.2 False True 73455.35965507237 77754.5462958122 73019.80169434154 83659.08508018714 76785.38952031532 74879.49910138131 74207.99267173363 77792.01486421136 72525.59411441497 80920.92838967466 0.9077424235835277 0.9608706652670276 0.9023599104389256 1.0338374354447206 0.9488940753442093 0.9253415722172532 0.9170432686385542 0.9613336921890463 0.8962526203996083 1.0 16.304225251293104 -5.486073285403359 0.003062451105968989 1.880834072136172 6.807385190882775e-08 0.053434682870868944 0.04150625425080955 288177.3868030561 175.4557113666918 52945.053281395034 54820.93744247352 3.2653272647163833e-06 5.486073285403359 -1.8808340040623202 NDAPT(ph)PGTSTTPGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NDAPTPGTSTTPGLR 15 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 NDAPT(0.317)PGT(0.317)S(0.102)T(0.2)T(0.064)PGLR 107.63 0.0020009 6508200.0 32431.0 24355.0 26579.0 30862.0 41599.0 31516.0 21534.0 25172.0 23978.0 22957.0 True False 37920.92775855254 26772.803443412387 27212.74416141881 29132.902195953986 33447.97457092014 29863.24547925284 19494.143627340967 24511.26167193861 24328.632888080716 27118.922372487992 1.398319860859336 0.9872369954704859 1.0034596429622882 1.074264743849452 1.2333814047439045 1.1011958760407439 0.7188391691816514 0.9038434984719437 0.8971091311785305 1.0 14.72701223063593 -7.15108211507844 7.5009492294890805 0.8725649962203749 1.1240190641960701 0.48236454427999265 0.12826944703956583 0.2447553113475569 14.835583191577376 0.04905701282922102 0.037963755949665556 7.061840185148318e-08 7.15108211507844 0.25145406797569525 NDAPTPGTST(ph)TPGLR ddPTM_PC-9_AZD4547_30min_R2 2 NDAPTPGTSTTPGLR 15 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 NDAPT(0.117)PGT(0.299)S(0.082)T(0.385)T(0.117)PGLR;NDAPT(0.003)PGT(0.015)S(0.015)T(0.483)T(0.483)PGLR 151.11 0.00034966 15560300.0 49855.0 47408.0 50609.0 84271.0 71822.0 65901.0 54078.0 76275.0 64548.0 64804.0 True False 65707.85295158005 62731.708886031316 49937.89159266683 64843.62292397119 61850.755037962066 61780.200052173626 58890.83723703259 64488.4513751317 67959.87550264627 62535.231684802486 1.0507333415308764 1.0031418641289944 0.7985561138458673 1.0369134514573117 0.9890545436804264 0.9879262999066757 0.9417225402451724 1.0312339082738842 1.0867454020988636 1.0 15.932381597422047 -7.8907281673584 5.864244843133469 1.0481629856253243 0.9709671089170135 0.16656462665783345 0.06840311124282593 0.35228294296960866 16.65907291823955 0.03879607132704966 0.018282811655461143 1.2860913955500789e-08 7.8907281673584 -0.07719587670831074 NDAPTPGTST(ph)TPGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NDAPTPGTSTTPGLR 15 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 NDAPT(0.004)PGT(0.06)S(0.311)T(0.528)T(0.098)PGLR 81.65100000000001 0.021034999999999998 7656300.0 33992.0 37349.0 34105.0 34755.0 43918.0 32401.0 33202.0 35726.0 34472.0 32671.0 True False 39746.174227397205 41056.76188905805 34918.19254393278 32807.790027230294 35312.58316800093 30701.834521299395 30056.866198336334 34788.230354825944 34976.08778538322 38593.993676506325 1.0298538824602714 1.0638122147501647 0.904757171196534 0.8500750220934425 0.9149761349911056 0.7955080984528637 0.7787964741423774 0.9013897511208565 0.9062572813415404 1.0 15.236088720116214 -5.349752000897189 3.9558978778838885 0.8685800959980552 1.0476925865705866 0.5427681878154309 0.06046921925089371 0.15394482756601136 4.38761351240964 0.016207405979386826 0.03731720592564743 4.469387387617664e-06 5.349752000897189 0.17911249057253142 NDAPTPGTSTT(ph)PGLR ddPTM_PC-9_AZD4547_30min_R2 2 NDAPTPGTSTTPGLR 15 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 NDAPTPGT(0.022)S(0.07)T(0.219)T(0.689)PGLR;NDAPT(0.001)PGT(0.104)S(0.059)T(0.194)T(0.642)PGLR 115.58 0.00038562 13660000.0 66809.0 60501.0 69308.0 104885.0 86800.0 82589.0 63114.0 92040.0 72393.0 90561.0 True False 88052.87228647304 80056.76508846143 68388.93063495735 80705.3837070964 74749.31827706173 77424.69677408485 68731.02373198104 77817.33286879228 76219.54618676132 87390.48695462328 1.0075796045420102 0.9160810046753736 0.7825672223392882 0.9235030781897569 0.8553484581894438 0.8859625283274474 0.7864817570780788 0.8904554211855831 0.8721721189897663 1.0 16.415188620712854 -4.8698721031363705 3.8121434010618196 0.8679479306529142 1.00997966341029 0.30570374380836274 0.05978488382297621 0.24778439712065956 6.031736795576664 0.013963512649201098 0.0821262022220079 1.3493602017741848e-05 4.8698721031363705 0.1420317327573758 NDAPTPGTSTT(ph)PGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NDAPTPGTSTTPGLR 15 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 NDAPTPGT(0.01)S(0.033)T(0.225)T(0.732)PGLR;NDAPTPGT(0.001)S(0.009)T(0.215)T(0.774)PGLR 137.27 4.1932e-05 14999800.0 88684.0 84280.0 83533.0 94243.0 110974.0 88963.0 86317.0 83190.0 64026.0 71104.0 True False 103696.44961115849 92646.76141288417 85524.74352066664 88962.87024992848 89229.44133352464 84297.62366958904 78140.42887903731 81006.35064709088 64962.25912470834 83994.59234104559 1.2345610201918344 1.1030086441363742 1.0182172582421514 1.059149973473412 1.062323643065304 1.0036077480716026 0.930303090962827 0.9644234038088849 0.7734100174085049 1.0 16.358008828227888 -2.224501622176894 0.2857409940082335 0.9039988649685217 2.5545841359044523 0.6485528529486392 0.06722899417105048 22.555105719439904 0.4586600261828513 0.07462619824703468 17.32126073097308 0.005963460923578426 2.224501622176894 1.6505852709359305 NDAPTPGTSTT(ph)PGLR ddPTM_PC-9_Lapatinib_30min_R1 2 NDAPTPGTSTTPGLR 15 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 NDAPT(0.001)PGT(0.011)S(0.034)T(0.226)T(0.728)PGLR;NDAPT(0.001)PGT(0.01)S(0.033)T(0.225)T(0.732)PGLR 137.27 1.7241e-05 18922700.0 127280.0 99588.0 104690.0 105792.0 97087.0 89180.0 75985.0 72621.0 96153.0 78109.0 True False 125464.96385970655 99357.4101046683 96082.79231508635 113572.29659176621 91376.53354038614 85365.97928873358 79919.13150253963 75995.23677599474 85323.23660402239 91610.03657629949 1.3695547840460713 1.0845690474309138 1.0488238615106504 1.239736396100824 0.9974511194991296 0.931840903890859 0.8723840147796161 0.8295514292552474 0.9313743318174422 1.0 16.483218044745513 -6.4953201205479045 2.8282668414782366 0.8994725098634353 1.168954310316447 0.6540020005550697 0.09281149612047492 0.17257334526981866 2.77326092416509 0.03193248249493091 0.03467667015453631 3.196538057550284e-07 6.4953201205479045 0.26948180045301173 NDCRS(ph)PTHLTVSSTNTLR ddPTM_PC-9_Lapatinib_30min_R1 1 NDCRSPTHLTVSSTNTLR 18 1 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 NDCRS(0.5)PT(0.5)HLTVSSTNTLR 50.251999999999995 0.029587000000000002 3623600.0 14765.0 12400.0 29360.0 10445.0 18460.0 18653.0 13190.0 13768.0 26372.0 11658.0 True False 14554.448392430615 12371.288561853731 26946.134132877443 11213.160143498577 17374.2190937564 17855.254672266743 13872.91366083434 14407.71154255511 23401.70765052858 13673.069766691442 1.0644609177586641 0.9047923233735747 1.9707450186877653 0.8200909038593969 1.270688981349398 1.3058702235077742 1.0146158761384902 1.0537291031494118 1.7115181923182154 1.0 13.739049561044494 NDDDEEEAAR ddPTM_PC-9_AZD4547_30min_R2 2 NDDDEEEAAR 10 0 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;C9JE79;F8WE61;C9JEK3;Q05682-5;E9PGZ1;Q05682-4;C9J813 E7EX44;Q05682-5 CALD1 Caldesmon 0 ; 117.25 0.0044808999999999995 14046300.0 20777.0 25932.0 22695.5 28486.0 28374.0 30920.0 22413.0 25942.0 28025.0 25585.0 False True 27383.653811553097 34314.01187210102 22394.542841023744 21918.992804312795 24434.75987089106 28986.56751207434 24407.713580265765 21933.259987855337 29506.34428582855 24689.276937467923 1.1091314614400978 1.3898346216865836 0.9070554353512986 0.8877940354360478 0.989691189935554 1.174054938323647 0.9885957228348449 0.8883719050747042 1.1951076720699887 1.0 14.59159696515917 -5.2680535669342525 24.93583144244611 1.000732873395827 1.2494830446296012 0.40514760540038997 0.11901456411775196 427.5312303802454 1611820.3827362815 0.030837973436143813 0.06669300113416708 5.394440820707321e-06 5.2680535669342525 0.2487501712337743 NDDDEEEAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NDDDEEEAAR 10 0 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;C9JE79;F8WE61;C9JEK3;Q05682-5;E9PGZ1;Q05682-4;C9J813 E7EX44;Q05682-5 CALD1 Caldesmon 0 ; 120.77 0.0031248 13692700.0 45504.0 49712.0 48783.0 49099.0 61054.0 56732.0 55160.0 48852.0 51668.0 43778.0 False True 53206.92845503303 54647.07882483746 49946.17173055773 46348.142211105755 49090.90697980617 53756.874049021826 49934.84547618313 47569.68676297256 52423.54675374739 51714.604853542696 1.0288569081348806 1.0567049478498312 0.9658039904202456 0.8962292633263867 0.9492658238196556 1.0394911495749197 0.9655849758032591 0.9198501448032201 1.0137087366753055 1.0 15.658284152821443 -5.268388425288689 23.94597179486863 0.9650079812180113 1.0427809309365026 0.3434943707670839 0.04068197266029962 296.1401388452496 1020486.6646847482 0.011006530400595559 0.023787103833938693 5.39028309493022e-06 5.268388425288689 0.07777294971849125 NDDDEEEAAR ddPTM_PC-9_Lapatinib_30min_R1 2 NDDDEEEAAR 10 0 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;C9JE79;F8WE61;C9JEK3;Q05682-5;E9PGZ1;Q05682-4;C9J813 E7EX44;Q05682-5 CALD1 Caldesmon 0 ; 125.23 0.0017808 18140000.0 18013.0 20273.1 21697.0 18966.2 21226.0 20835.7 21437.0 20059.3 19881.2 17540.9 False True 17756.13131682037 20226.158882525557 19913.156412842036 20361.03761738848 19977.528411921623 19944.60568138896 22546.902967953414 20991.328308074913 17641.969897682742 20572.821193219916 0.8630868440480187 0.9831495006232491 0.9679351327568393 0.9897056619584468 0.9710641153341438 0.969463813157624 1.0959558125836473 1.0203427187221616 0.8575377062771011 1.0 14.328452026712391 -4.760099199249293 5.86279652086644 0.9871837919101247 0.8580226123585509 0.29734176190497585 0.05554680966055287 0.18148923291984337 22.69649185672558 0.0140053399029667 0.09443507307770427 1.7374039348023537e-05 4.760099199249293 -0.1291611795515738 NDDDEEEAARER ddPTM_PC-9_AZD4547_30min_R2 1 NDDDEEEAARER 12 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;C9JE79;F8WE61;C9JEK3;Q05682-5;E9PGZ1;Q05682-4;C9J813 E7EX44;Q05682-5 CALD1 Caldesmon 0 71.176 0.036325 2992000.0 4724.5 2614.7 4866.9 15357.0 11745.0 6808.5 4931.1 7422.1 5339.5 7952.2 False True 6226.792724295256 3459.8506417546855 4802.3617260240335 11816.680913284838 10114.40948345723 6382.763418692049 5369.958347193527 6275.184987890723 5621.735069194702 7673.795898461295 0.8114358013540361 0.4508656064788529 0.6258130642993743 1.5398742772992242 1.3180451522675123 0.8317609046615226 0.6997786256304106 0.81774197162958 0.7325885576813347 1.0 12.905724678454298 -5.575032076896342 24.999963080505566 0.9866303993098544 0.6079372560525972 0.2867708413653838 0.26105660213937343 130.4008153724257 62507.58473705755 0.0788690850080586 0.13660529155239476 2.6605285464796534e-06 5.575032076896342 -0.3786931432572572 NDDDEEEAARER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NDDDEEEAARER 12 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;C9JE79;F8WE61;C9JEK3;Q05682-5;E9PGZ1;Q05682-4;C9J813 E7EX44;Q05682-5 CALD1 Caldesmon 0 84.352 0.013294 2335500.0 7250.5 3617.0 8210.9 11204.0 12472.0 14597.0 13448.0 20275.0 16689.0 10519.0 False True 8477.866446097416 3976.0718560797623 8406.678996011653 10576.27620385809 10028.20113100113 13831.507623450116 12174.108084911362 19742.802733138233 16933.045052513924 12426.01143164182 0.6822677166149408 0.3199797358913594 0.6765388107244722 0.8511400671116774 0.8070329877103716 1.1131091983570298 0.9797277390161572 1.5888286311136655 1.3627095987852798 1.0 13.601075666188198 -6.5422724043238 0.791567480364424 1.3210032922578845 0.5043718732585177 0.687097515898734 0.1922020407039509 0.35026770699787835 0.48737709052743194 0.11893468445614239 0.14593814989970194 2.868980495045852e-07 6.5422724043238 -0.8166314189993668 NDDSMS(ph)PNQWR ddPTM_PC-9_Lapatinib_30min_R1 2 NDDSMSPNQWR 11 0 Q99990;H0Y5G3 Q99990 VGLL1 Transcription cofactor vestigial-like protein 1 1 NDDS(0.294)MS(0.706)PNQWR;NDDS(0.027)MS(0.973)PNQWR 122.1 0.00070294 4565400.0 19867.7 20731.2 22425.9 19280.2 21246.8 23522.0 25345.0 22206.0 26378.0 23280.9 True False 19584.382954710043 20683.19818012113 20582.129068477392 20698.13022486176 19997.104996815997 22516.018892460124 26657.240085962556 23237.77182698856 23407.0318673458 27304.972545150704 0.7172460225816335 0.7574883346218348 0.7537868435664378 0.7580351963597817 0.7323612929384701 0.8246123981713694 0.9762778571515838 0.8510454199711521 0.8572442923588593 1.0 14.736876085748374 -6.990303157980589 4.197037786783974 0.9088470350795756 0.7469475995551113 0.7713021687326265 0.04523866546403634 0.10439061865565233 4.363462506057577 0.016800846449388646 0.013971056960366216 1.0225789348811754e-07 6.990303157980589 -0.1618994355244644 NDELLSDLT(ph)RTPPPPSSTFPK ddPTM_PC-9_AZD4547_30min_R2 1 NDELLSDLTRTPPPPSSTFPK 21 1 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 NDELLS(0.018)DLT(0.542)RT(0.434)PPPPS(0.002)S(0.003)T(0.001)FPK 62.19 0.0053901 6697400.0 35936.0 23679.0 36956.0 72956.0 63250.0 41915.0 30036.0 41079.0 33798.0 43204.0 True False 47362.90048476544 31332.773681917322 36465.93929337855 56137.12135896389 54468.8292744717 39294.04842395202 32709.14581255798 34731.18445151144 35584.49328001546 41691.44111027416 1.1360341409041304 0.7515397128883579 0.8746624804099691 1.3464903074585692 1.3064750899447504 0.9424967661832314 0.7845530147552842 0.8330531045843969 0.8535203469195085 1.0 15.347463620890105 -6.9929534798453785 24.986604258223835 0.8552487089611647 1.073363489889361 0.2553503188892776 0.17388673646715785 271.0001834417847 960947.2886031248 0.06840477332476193 0.06019734756272132 1.0163575558206333e-07 6.9929534798453785 0.21811478092819625 NDELLSDLT(ph)RTPPPPSSTFPK ddPTM_PC-9_Lapatinib_30min_R1 3 NDELLSDLTRTPPPPSSTFPK 21 1 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 NDELLS(0.044)DLT(0.554)RT(0.402)PPPPSSTFPK;NDELLS(0.159)DLT(0.72)RT(0.121)PPPPSSTFPK;NDELLS(0.086)DLT(0.511)RT(0.403)PPPPSSTFPK 64.723 0.0032683 9221400.0 55378.0 35559.5 49079.0 48474.0 41745.2 42656.0 33116.0 34083.2 49589.0 32923.5 True False 54588.29956491857 35477.16416251916 45043.91407041868 52038.939664523685 39289.829410221 40831.702315992625 34830.58444216752 35666.8298988389 44003.76462468008 38614.28310719381 1.413681549217958 0.9187575505165806 1.1665091371857434 1.347660385667729 1.0174947260098512 1.0574248446525143 0.9020129765319561 0.9236693531206382 1.1395722277822689 1.0 15.236846966846448 -6.425940087941116 9.665079907942335 0.9982108770170707 1.1874827654345093 0.3438713848095808 0.1370341480255379 0.533379182586138 49.90797164488223 0.04224697216763795 0.0478861211936696 3.750247343194066e-07 6.425940087941116 0.18927188841743858 NDELLSDLTRT(ph)PPPPSSTFPK ddPTM_PC-9_AZD4547_30min_R2 3 NDELLSDLTRTPPPPSSTFPK 21 1 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 NDELLS(0.043)DLT(0.1)RT(0.857)PPPPSSTFPK;NDELLS(0.114)DLT(0.094)RT(0.791)PPPPSSTFPK;NDELLS(0.056)DLT(0.185)RT(0.758)PPPPSSTFPK 73.435 0.0012902999999999999 16176000.0 70343.0 34551.5 61880.0 107786.0 88770.0 67208.0 56042.3 63358.0 54445.2 75637.0 True False 92710.6107747064 45719.59668359163 61059.43076832622 82937.60297709973 76445.81778173667 63005.4731355592 61029.956131679246 53567.476922000584 57323.06211992125 72988.97165211101 1.2702002600693578 0.6263904758311432 0.8365569398532585 1.1363032126607715 1.0473612115827868 0.8632190824096497 0.8361531167005299 0.7339119281926654 0.7853660741124215 1.0 16.155390874435824 -6.94641377201872 6.623984817720114 0.8210574997531682 0.9638019421905394 0.13225069913904186 0.17372743988111558 0.44646310913021414 42.047611496658384 0.06280780360041192 0.0551165442344061 1.1313219879219887e-07 6.94641377201872 0.14274444243737117 NDELLSDLTRT(ph)PPPPSSTFPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NDELLSDLTRTPPPPSSTFPK 21 1 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 NDELLSDLT(0.042)RT(0.957)PPPPSSTFPK;NDELLS(0.006)DLT(0.124)RT(0.87)PPPPSSTFPK 83.395 0.00038354 11529100.0 30434.0 17030.6 21933.0 46680.0 51739.0 50298.0 50755.0 72099.0 50718.0 38187.0 True False 35585.87510110045 18721.285416685645 22455.965901365707 44064.67093860192 41601.11436151917 47660.28433543149 45947.11896562139 70206.477645205 51459.654800970806 45110.0008118743 0.7888688641240987 0.41501407846921706 0.49780459980516395 0.9768270925635361 0.9222148883351053 1.0565347700655745 1.0185572631053188 1.556339534064574 1.1407593410511554 1.0 15.461159691571845 -6.278141772534983 0.9531215070616658 1.2185555421633998 0.5391568587265656 0.6262327995279342 0.18735292629759304 0.34982380071208946 0.6761471515517935 0.09080987906352776 0.14145353639903382 5.270577788426117e-07 6.278141772534983 -0.6793986834368342 NDELLSDLTRT(ph)PPPPSSTFPK ddPTM_PC-9_Lapatinib_30min_R1 1 NDELLSDLTRTPPPPSSTFPK 21 1 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 NDELLS(0.002)DLT(0.047)RT(0.951)PPPPSSTFPK 91.50299999999999 0.00029795 4101700.0 17602.0 12244.0 14766.0 12163.0 12557.0 15676.0 8607.1 7069.0 14056.0 9900.4 True False 17350.99225218854 12215.649770269121 13551.99647840833 13057.507594578565 11818.421948011865 15005.574022540797 9052.733523136254 7397.451546653254 12472.865263758144 11611.670948546225 1.4942717830254115 1.052014806861067 1.1671013188765078 1.1245158127920734 1.017805447672587 1.2922837797448512 0.7796236702926594 0.6370703733711478 1.074166269353313 1.0 13.503287974123491 -7.267454437512346 24.91397159115818 0.8424709282825357 1.1729734669661687 0.45659992108555414 0.1682841754544068 415.9003159667942 1722623.1911577785 0.06708795654963115 0.04656431405044022 5.401887838101896e-08 7.267454437512346 0.330502538683633 NDESSEQENNGDDATASSNPLAGQRK ddPTM_PC-9_Lapatinib_30min_R1 1 NDESSEQENNGDDATASSNPLAGQRK 26 1 H7C566;C9JWE6;E7ENB6;B7ZAG0;Q9UPQ7-3;Q9UPQ7 H7C566 PDZRN3 E3 ubiquitin-protein ligase PDZRN3 0 44.582 0.028475 14555000.0 28052.0 23664.0 27967.0 23434.0 25992.0 31638.0 22594.0 25892.0 26466.0 22946.0 False True 27651.97333589324 23609.20746191183 25667.66121574196 25157.41453353237 24463.201662238127 30284.916491780165 23763.80676670896 27095.036843393125 23485.12038066471 26912.185526376878 1.027488953239836 0.8772683080224841 0.9537561039249247 0.9347964143928541 0.9090009296443621 1.1253235625214326 0.8830128918150418 1.0067943689239596 0.8726574940428651 1.0 14.715971935895055 NDFTEEEEAQVR ddPTM_PC-9_AZD4547_30min_R2 2 NDFTEEEEAQVR 12 0 E5RJR5;P63208 E5RJR5 SKP1 S-phase kinase-associated protein 1 0 ; 122.42 0.0024119 0.0 19983.9 27842.0 20134.7 36599.0 54308.0 51337.0 42489.0 39726.0 46523.0 36042.0 False True 26338.364509057883 36841.382020015255 19867.70072222074 28161.665998913297 46768.27162431634 48126.88927449417 46270.43868790039 33587.259512664445 48982.1108014131 34780.18055033102 0.7572808447886913 1.0592636794021653 0.5712362732985194 0.8097044222688853 1.344681680321847 1.3837446647192901 1.3303679841725264 0.9657011257908718 1.408334000179505 1.0 15.085977801509392 -6.252835654469479 23.86953796486148 1.2489151075756646 0.8016396214539401 0.5889169937709543 0.1797377853454815 241.82933953689724 670911.8169637534 0.05290054779257522 0.06712526165378704 5.586815707789357e-07 6.252835654469479 -0.4472754861217245 NDFTEEEEAQVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NDFTEEEEAQVR 12 0 E5RJR5;P63208 E5RJR5 SKP1 S-phase kinase-associated protein 1 0 ; 129.74 0.0017211 0.0 7587.5 31298.0 12650.2 33106.0 59668.0 58449.0 59349.0 41160.0 52167.0 31229.0 False True 8871.913890044014 34405.058598723925 12951.82874415066 31251.178151100154 47976.48373032191 55383.831546416084 53727.03307044945 40079.59361262487 52929.84368473214 36890.570491372026 0.24049272678282324 0.9326247369031766 0.35108778670635726 0.8471318750250606 1.3005080455869518 1.5013004897652442 1.456389325370155 1.086445481291722 1.4347797548186842 1.0 15.170964479200487 -6.1090692768673955 3.132085690394577 1.3207278341590887 0.5516895901139275 0.7106853555052906 0.22629199041252732 0.13590023228913933 2.535621678235798 0.06656781590333799 0.09114249272047781 7.779124517511835e-07 6.1090692768673955 -0.7690382440451612 NDFTEEEEAQVR ddPTM_PC-9_Lapatinib_30min_R1 2 NDFTEEEEAQVR 12 0 E5RJR5;P63208 E5RJR5 SKP1 S-phase kinase-associated protein 1 0 ; 190.66 0.00066736 32730000.0 11825.900000000001 37090.0 27818.0 36124.0 46658.0 50779.0 49128.0 22380.0 46226.0 28337.0 False True 11657.260497395553 37004.12038380281 25530.911420585304 38780.679466131376 43913.66817315739 48607.3005416305 51671.60745484983 23419.856502206803 41019.541098639995 33235.01269332092 0.3507524009382508 1.113407740362902 0.7681932200891299 1.1668621830833525 1.321307398868017 1.4625329314647404 1.5547340971900403 0.7046742156627303 1.2342267318250038 1.0 15.020416284448142 -4.66826065958898 1.0055706988478792 1.2117834717825668 1.1695886445317546e-16 0.43786251893637673 0.2637140471142107 2.4104535651865406 1.688101209383564 0.08963669710235407 3.3372290502753996 2.1465417526378633e-05 4.66826065958898 -1.2117834717825666 NDGQASSS(ph)PPSESMGQAK ddPTM_PC-9_AZD4547_30min_R2 1 NDGQASSSPPSESMGQAK 18 0 Q5VYV7 Q5VYV7 SLX4IP Protein SLX4IP 1 NDGQASS(0.029)S(0.947)PPS(0.023)ESMGQAK 195.17 7.2416e-54 0.0 6515.3 7067.0 8011.6 7250.0 7316.1 5314.4 6279.9 7447.2 6104.4 8219.5 True False 8587.029873341275 9351.26954728281 7905.360949313556 5578.624511383414 6300.385800078453 4982.089727883822 6838.798934221695 6296.406359631345 6427.066121620407 7931.737806821087 1.0826164558738507 1.178968565910104 0.9966745172180493 0.7033294149720812 0.7943260296199259 0.6281208291579374 0.8622068833819124 0.7938243185770211 0.8102973494778531 1.0 12.953421272988946 -5.573497670453435 4.288825286000493 0.7864952861637687 1.1245079593552332 0.6712116651805905 0.09470521733250724 0.10558208065056103 4.094404714868305 0.024973584053103886 0.046453816456153936 2.6699450886210853e-06 5.573497670453435 0.33801267319146444 NDGQASSS(ph)PPSESMGQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NDGQASSSPPSESMGQAK 18 0 Q5VYV7 Q5VYV7 SLX4IP Protein SLX4IP 1 NDGQAS(0.019)S(0.127)S(0.583)PPS(0.261)ES(0.01)MGQAK 85.56299999999999 0.012996 0.0 6521.7 7342.1 7725.5 5981.0 7879.4 6911.6 8556.1 5675.5 3588.4 5550.0 True False 7625.695000553549 8070.975165751514 7909.705219121899 5645.903960663625 6335.488132746169 6549.143528823577 7745.6042672003305 5526.524138689323 3640.8735614141656 6556.171066224173 1.1631324020569427 1.2310501181598585 1.2064519273865215 0.8611587317710444 0.9663396620910474 0.9989281034113341 1.1814219288913665 0.8429499601010497 0.5553353511733512 1.0 12.678637782963628 -5.609697733681814 0.42466711793119094 0.847583771215227 1.3500145550982139 0.3618714865560291 0.15943213312973556 3.2680329655928735 0.7686610452508897 0.14677062372935173 0.7790425651756964 2.4564179728394184e-06 5.609697733681814 0.5024307838829869 NDHIQVGR ddPTM_PC-9_AZD4547_30min_R2 2 NDHIQVGR 8 0 Q8IXB1-2;Q8IXB1 Q8IXB1-2 DNAJC10 DnaJ homolog subfamily C member 10 0 ; 109.29 0.0031728000000000004 2041740.0 26710.0 26772.0 30451.0 39569.0 33267.0 30900.0 32658.0 36434.0 29912.0 34506.0 False True 35203.22439748678 35425.52544500572 30047.19984367005 30446.978384955877 28648.451280218953 28967.81811523601 35564.498733070934 30803.962470030132 31493.087253441685 33297.955442809 1.0572187970504732 1.0638949140841676 0.9023737176679724 0.9143798164199654 0.8603666771500186 0.8699578616768159 1.0680685423510414 0.9251007174580904 0.9457964260758511 1.0 15.023145975372229 -5.254072860246725 24.45528702171457 0.9320001741979225 1.0605568816131425 0.42496997103869305 0.05793756501120026 396.59468348797213 1316598.693267147 0.015462551616996478 0.03918794830936631 5.570922794368522e-06 5.254072860246725 0.12855670741522007 NDHIQVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NDHIQVGR 8 0 Q8IXB1-2;Q8IXB1 Q8IXB1-2 DNAJC10 DnaJ homolog subfamily C member 10 0 ; 88.177 0.011555 717990.0 21938.9 22348.0 22542.8 26048.0 23879.0 17972.8 22913.0 17156.0 15772.8 15992.900000000001 False True 25652.72245697353 24566.56174721332 23080.30584604508 24588.61500875542 19200.08136683578 17030.274728693854 20742.51476424555 16705.673178284553 16003.447360794036 18892.286170273266 1.3578410905789533 1.3003488051048286 1.2216788184355158 1.3015161207670696 1.0162921095831603 0.9014406501787349 1.0979356641804203 0.8842589524485757 0.8470889767684773 1.0 14.205509673490985 -6.33139823630201 3.6126347886891716 0.9489542424638985 1.2928884846399387 0.8417967716981782 0.0720866301788649 0.09522542339273592 2.4417013361804996 0.023830255795791486 0.02792470324785326 4.6623166240802817e-07 6.33139823630201 0.3439342421760402 NDHIQVGR ddPTM_PC-9_Lapatinib_30min_R1 2 NDHIQVGR 8 0 Q8IXB1-2;Q8IXB1 Q8IXB1-2 DNAJC10 DnaJ homolog subfamily C member 10 0 ; 70.256 0.032425999999999996 2212900.0 24197.5 36461.0 28688.0 28664.0 32637.0 26571.0 30567.0 29890.0 30141.0 23732.3 False True 23852.439212721976 36376.576794657165 26329.38337888244 30772.046180300906 30717.355826810795 25434.620270026273 32149.609694520346 31278.79851880972 26746.203181199093 27834.396433698003 0.8569411328727348 1.3068929617822602 0.9459297399029102 1.105540271139 1.1035754233069164 0.9137837901609243 1.1550316807156662 1.1237462466023411 0.9609047296897203 1.0 14.764581179421004 -8.27722926769556 23.308706982127024 0.9804523298424818 1.06883592249099 0.06623104157825632 0.12429029478089111 1027.4160528729963 1516615.9337579655 0.1088826546531976 0.028584322623652646 5.281663547219228e-09 8.27722926769556 0.08838359264850826 NDHQEDFWK ddPTM_PC-9_AZD4547_30min_R2 1 NDHQEDFWK 9 0 A6NKB8;Q9H4A4 A6NKB8 RNPEP Aminopeptidase B 0 83.86200000000001 0.011498999999999999 5533400.0 34544.0 36399.0 34730.0 50326.0 39865.0 51044.0 35566.0 41227.0 42899.0 32307.0 False True 45528.273440164085 48164.26492876003 34269.45750782113 38724.11822894916 34330.432869989156 47852.21061081248 38731.30509952847 34856.31445221309 45166.55355995575 31175.941763485494 1.4603656173584663 1.544917721945835 1.0992276598347666 1.2421154274256565 1.101183506513934 1.5349082627187511 1.242345953599776 1.1180516924444026 1.4487630847725221 1.0 14.928145521223914 -14.52287874525844 0.04811223644694856 1.2248594277482278e-09 1.8340513728755967 0.2278148087088836 0.16864040234749422 1018.7333814140495 3.618443838232828 139.47291003094455 32.84165473657521 3.000000000151261e-15 14.52287874525844 1.8340513716507374 NDHQEDFWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NDHQEDFWK 9 0 A6NKB8;Q9H4A4 A6NKB8 RNPEP Aminopeptidase B 0 88.134 0.0082057 0.0 39814.0 39755.0 34809.0 48857.0 46565.0 35930.0 48673.0 39940.0 36959.0 39097.0 False True 46553.72383765568 43701.613668358 35638.97857386763 46119.70068653114 37440.92251964941 34045.76754884993 44062.34107799602 38891.61731992803 37499.45545544145 46184.97660831832 1.007984138055641 0.9462300704183306 0.7716573914524564 0.9985866416618381 0.8106731943847292 0.7371610867659937 0.9540405628366173 0.8420837288661376 0.8119405531687001 1.0 15.49513601696 -5.032042335889623 7.495489113283264 0.8611516537912292 0.9935185962405766 0.21996443712310043 0.08702169667339192 0.26113343086340424 53.90248967821758 0.021257470870274374 0.0606884693220591 9.288758337031657e-06 5.032042335889623 0.13236694244934744 NDHQEDFWK ddPTM_PC-9_Lapatinib_30min_R1 1 NDHQEDFWK 9 0 A6NKB8;Q9H4A4 A6NKB8 RNPEP Aminopeptidase B 0 120.09 0.00013637 0.0 39519.0 36566.0 32317.0 36727.0 35382.0 42092.0 37155.0 29456.0 37623.0 27087.0 False True 38955.45181310298 36481.33367360832 29660.02100722753 39428.0260976804 33300.900323688424 40291.82328124443 39078.70409918876 30824.633294414794 33385.501552246234 31768.951858841214 1.2262114276288842 1.1483329332269319 0.9336166058929396 1.2410867778348718 1.048221561468383 1.268276758398352 1.230091073600002 0.9702754258742213 1.0508845775141662 1.0 14.955329872087587 -7.771785067148391 24.996373385259012 1.0079349728964928 1.1510402356683538 0.32981433456624043 0.09743227278766176 272.45297997709264 658267.2255671759 0.05322818802379482 0.026017298778494548 1.6912777399068577e-08 7.771785067148391 0.14310526277186097 NDKQMVQYIYK ddPTM_PC-9_Lapatinib_30min_R1 1 NDKQMVQYIYK 11 1 P50591 P50591 TNFSF10 Tumor necrosis factor ligand superfamily member 10 0 101.9 0.031389 0.0 19119.0 20953.0 22789.0 20565.0 22067.0 19061.0 21499.0 20557.0 20364.0 23351.0 False True 18846.359554004815 20904.48461584848 20915.376388083918 22077.41870282892 20769.06244539124 18245.805463361205 22612.113024585095 21512.15326701811 18070.391877573336 27387.18923674831 0.6881450809386692 0.7632942700011984 0.7636919658779562 0.8061221073831591 0.7583495431332243 0.666216795949212 0.8256456268335859 0.7854823319420076 0.6598118456539661 1.0 14.74121358855424 -10.764512199558254 4.023900054187584 1.0002180407053867 0.7505612160504338 0.6612942947720203 0.05439170380037204 26000662.734894652 36364.83406849934 53345.77162696483 0.012997763399850166 1.7198390293853593e-11 10.764512199558254 -0.24965682465495287 NDKS(ph)EEEQSSSSVK ddPTM_PC-9_AZD4547_30min_R2 6 NDKSEEEQSSSSVK 14 1 B4DY08;B2R5W2;G3V4W0;G3V5V7;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 NDKS(1)EEEQSSSSVK;NDKS(1)EEEQSSSSVK;NDKS(1)EEEQSSSSVK;NDKS(1)EEEQSSSSVK;NDKS(1)EEEQSSSSVK;NDKS(1)EEEQSSSSVK 221.47 2.093e-15 1307409000.0 220051.0 218852.0 176553.7 183710.6 188987.1 227771.0 231720.0 205746.0 214557.0 213266.0 True False 290022.6406548613 289591.62911588216 174212.48257986188 141358.95947047631 162749.50331980255 213528.44336328245 252342.63109887915 173952.68327273513 225898.04499320337 205799.62225311808 1.4092476821855155 1.4071533559945324 0.8465150745786774 0.6868766712147577 0.7908153646639491 1.0375550791859982 1.2261569206794591 0.8452526849577323 1.0976601536972974 1.0 17.650880808592632 -5.254690700105533 24.63824653615394 0.9349697320314575 1.4082006085601244 0.6084256317954067 0.1497387985761495 303.29234070602945 1107257.8521618608 0.042122223005741935 0.10611620326682909 5.563003073634411e-06 5.254690700105533 0.4732308765286669 NDKS(ph)EEEQSSSSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NDKSEEEQSSSSVK 14 1 B4DY08;B2R5W2;G3V4W0;G3V5V7;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 NDKS(1)EEEQSSSSVK;NDKS(0.999)EEEQSSSSVK;NDKS(0.994)EEEQS(0.006)SSSVK;NDKS(0.985)EEEQS(0.009)S(0.004)S(0.002)S(0.001)VK 137.73 7.2264e-05 342925600.0 108922.0 140930.0 89967.6 139026.0 133057.0 84475.1 125482.0 108776.8 89083.3 92839.0 True False 127360.34329243787 154920.59902607737 92112.76878802321 131236.8239483736 106985.43600766627 80045.07704608547 113595.43654899218 105921.52425854646 90385.97473345393 109669.97578688024 1.161305474708365 1.4126072146412423 0.8399087181985374 1.1966522560687334 0.9755216524855372 0.729872296148179 1.0357933949920826 0.9658206222675012 0.8241633508618569 1.0 16.74280908940228 -5.407299788236143 1.0073183539562232 0.9240208163658046 1.3156365531639982 0.37616092325755957 0.15100007427640305 0.8723496023448035 1.3382011793797663 0.05323348352102532 0.2977686593409807 3.914715557313727e-06 5.407299788236143 0.3916157367981936 NDKS(ph)EEEQSSSSVK ddPTM_PC-9_Lapatinib_30min_R1 7 NDKSEEEQSSSSVK 14 1 B4DY08;B2R5W2;G3V4W0;G3V5V7;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 NDKS(0.999)EEEQS(0.001)SSSVK;NDKS(0.965)EEEQS(0.022)S(0.007)S(0.002)S(0.003)VK;NDKS(1)EEEQSSSSVK;NDKS(1)EEEQSSSSVK;NDKS(0.997)EEEQS(0.002)SSSVK;NDKS(0.915)EEEQS(0.082)S(0.001)S(0.001)SVK;NDKS(0.93)EEEQS(0.029)S(0.021)S(0.01)S(0.01)VK 180.02 5.7489e-19 826922500.0 105196.8 186880.4 148714.0 178416.9 184331.1 173607.2 190255.1 172879.59999999998 153358.90000000002 156544.4 True False 103696.67434126975 186447.68991569726 136487.30897264107 191538.27400733106 173489.10710688608 166182.42475414922 200105.5781526463 180912.21734400818 136086.0057411896 183602.8909576984 0.5647878080806537 1.0154943037288793 0.7433832237646376 1.0432203600294123 0.9449148986812931 0.905118780468643 1.0898825018978056 0.9853451457128192 0.7411975107327883 1.0 17.48622924962371 -4.754487372581207 24.999626019652137 0.9411729767134762 0.564787161480149 0.5068852267159858 0.11130524305262042 198.48065038678303 713679.7301563752 0.026867621607964166 0.26088777308847605 1.7599998362958143e-05 4.754487372581207 -0.37638581523332726 NDKS(ph)EEEQSSSSVKK ddPTM_PC-9_AZD4547_30min_R2 3 NDKSEEEQSSSSVKK 15 2 B4DY08;B2R5W2;G3V4W0;G3V5V7;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 NDKS(1)EEEQSSSSVKK;NDKS(1)EEEQSSSSVKK;NDKS(1)EEEQSSSSVKK 99.413 0.0058113 51300000.0 47835.0 40853.0 40823.0 38786.0 40892.0 55145.0 48396.0 35229.1 46979.0 47013.0 True False 63045.53497019019 54057.9333260428 40281.66034672566 29844.486937726466 35214.85164729953 51696.77443251422 52703.1502445251 29785.252079182595 49462.21403047062 45367.089179643495 1.3896755579919182 1.191567153713246 0.8879048904199985 0.6578444303435249 0.7762202134648009 1.139521520276661 1.1617044689782157 0.656538751279362 1.0902664227500105 1.0 15.469358476734005 -5.062985983024525 3.0444038689811297 0.9112726730911298 1.3734670371200095 0.43529377764333477 0.17458506197200355 0.2540280204865859 4.401951992487216 0.0482729619223986 0.2017482287444305 8.649958363069257e-06 5.062985983024525 0.4621943640288797 NDKS(ph)EEEQSSSSVKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NDKSEEEQSSSSVKK 15 2 B4DY08;B2R5W2;G3V4W0;G3V5V7;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 NDKS(1)EEEQSSSSVKK;NDKS(1)EEEQSSSSVKK;NDKS(1)EEEQSSSSVKK 94.973 0.0082345 45827000.0 49160.0 45309.0 31442.1 56975.0 51629.0 42906.0 57180.0 45827.0 46263.0 47079.0 True False 57481.817045741496 49806.97808325075 32191.798908828267 53782.87546544225 41512.66807187755 40655.93382830377 51763.4964526496 44624.08980772013 46939.50885400273 55614.05002284104 1.0335844453359062 0.8955826461621608 0.5788429164142316 0.9670735262645552 0.7464420961039169 0.7310370996466923 0.9307629354702635 0.8023887810614896 0.8440224877476893 1.0 15.763161782959106 -8.582594446164055 17.40753825209051 1.0000000022701292 0.829790484526241 0.13286255669051206 0.12463040425337127 1592.4016663829232 464198.97353147325 0.1182347376834746 0.030528078003862227 2.6146017879946834e-09 8.582594446164055 -0.17020951774388815 NDKS(ph)EEEQSSSSVKK ddPTM_PC-9_Lapatinib_30min_R1 2 NDKSEEEQSSSSVKK 15 2 B4DY08;B2R5W2;G3V4W0;G3V5V7;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 NDKS(1)EEEQSSSSVKK;NDKS(1)EEEQSSSSVKK 115.53 0.00044589999999999994 47555000.0 49288.0 58682.0 44732.0 49352.0 61854.0 48076.0 42773.0 41088.0 47335.0 41302.0 True False 48585.144081687766 58546.12543441135 41054.30763051342 52981.51071344582 58215.86932964286 46019.90155062974 44987.57665010367 42997.09847911852 42003.63384035228 48440.99566854436 1.0029757524830771 1.208606978993804 0.8475116389313285 1.0937329008670622 1.2017892804677817 0.950019728444872 0.9287087523536762 0.8876179749343821 0.8671092173199849 1.0 15.563940898407221 -6.978274877980732 24.599772502726317 0.915475283712617 1.0682755712180416 0.340838788517256 0.1007980796996963 224.1441137856886 253801.6326191156 0.03537389537253286 0.03119433480318168 1.0512962663203508e-07 6.978274877980732 0.15280028750542463 NDKS(ph)EEEQSSSSVKKDETNVK ddPTM_PC-9_AZD4547_30min_R2 1 NDKSEEEQSSSSVKKDETNVK 21 3 B4DY08;B2R5W2;G3V4W0;G3V5V7;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 NDKS(0.997)EEEQS(0.001)S(0.001)SSVKKDETNVK 52.731 0.023149 14020000.0 46147.0 18646.0 32780.0 62076.0 55552.0 33673.0 25749.0 22565.0 23671.0 43145.0 True False 60820.786082771345 24672.954857596626 32345.315781928508 47765.337264639515 47839.56369731937 31567.42198687189 28040.61111757744 19078.097742115315 24922.20073469573 41634.50668231593 1.4608263896784612 0.5926083151617203 0.7768872110995142 1.1472535901314673 1.149036400559515 0.7582033390653818 0.6734944965611317 0.4582280243569849 0.5985948368467476 1.0 15.345492109450278 -6.946582932883254 5.221246913475302 0.6465902541878645 0.9936162294681098 0.29112437587107454 0.2525747706396517 0.2577961112158458 15.043067548093505 0.09176702492118272 0.07983642058715389 1.1308814155746594e-07 6.946582932883254 0.34702597528024526 NDKSEEEQS(ph)SSSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NDKSEEEQSSSSVK 14 1 B4DY08;B2R5W2;G3V4W0;G3V5V7;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 NDKSEEEQS(0.601)S(0.149)S(0.125)S(0.125)VK 57.196999999999996 0.032102 3693900.0 18148.0 24057.0 17770.0 22199.0 24063.0 16529.0 19924.0 15079.0 15124.0 15305.0 True False 21220.097960661442 26445.21997282578 18193.704193100275 20955.262000129045 19348.027887690834 15662.190142358486 18036.65448273156 14683.192227521142 15345.159888203054 18079.67534568666 1.1736990601285329 1.462704360957174 1.0063070185295566 1.1590507904296203 1.070153502081926 0.8662871341932075 0.9976204847635516 0.8121380471040465 0.8487519601320722 1.0 14.142081151253151 -5.999248239826157 0.7487958673323143 0.8827896580888218 1.3232977548492333 0.6030095449435682 0.11529451879256633 0.5289394496964125 0.5849687425044268 0.059294582736169686 0.1492002676936566 1.0017324908008635e-06 5.999248239826157 0.44050809676041147 NDKSEEEQSSS(ph)SVK ddPTM_PC-9_Lapatinib_30min_R1 1 NDKSEEEQSSSSVK 14 1 B4DY08;B2R5W2;G3V4W0;G3V5V7;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 NDKSEEEQS(0.015)S(0.004)S(0.49)S(0.49)VK 57.788000000000004 0.03105 4639100.0 12782.0 18490.0 14226.0 14006.0 21872.0 14702.0 18270.0 18623.0 13020.0 18433.0 True False 12599.726336068274 18447.187541022206 13056.39319394805 15036.047962646344 20585.5319620065 14073.229732035914 19215.93120420343 19488.292566603977 11553.550493321793 21619.119489571396 0.5828047873155109 0.853281168547162 0.6039280739553791 0.6954977037755591 0.9521910442252989 0.650962206801463 0.8888396779282702 0.9014378488450797 0.5344135545804712 1.0 14.400020145272466 -14.522878745280336 0.13305646742978097 1.7429707215957533 0.6626301977960724 0.2093828106749024 0.14396189545121496 234.94898779345291 1.9478798063974372 47.72914555728675 0.9927934846651265 3.0000000000000132e-15 14.522878745280336 -1.080340523799681 NDKSEEEQSSSS(ph)VK ddPTM_PC-9_AZD4547_30min_R2 2 NDKSEEEQSSSSVK 14 1 B4DY08;B2R5W2;G3V4W0;G3V5V7;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 NDKSEEEQS(0.058)S(0.013)S(0.037)S(0.892)VK;NDKSEEEQSSS(0.014)S(0.986)VK 100.27 0.00094374 13006400.0 41646.0 46584.0 37399.3 36251.5 35347.0 48943.0 43594.0 43759.0 50306.0 38379.0 True False 54888.561709387264 61641.36700022957 36903.360845731506 27894.276755091836 30439.679183632434 45882.58647294485 47473.78154723175 36997.05203178483 52965.07245826554 37035.36289165845 1.4820581580354901 1.664392142735374 0.9964357836505316 0.7531795175517106 0.8219084898041711 1.2388858347943739 1.2818500438650857 0.9989655600247338 1.430121600622819 1.0 15.176615853093438 -5.2633585596769334 24.996516553593384 1.059243917093743 1.5732251777309252 0.5096469965546129 0.1992710601902738 132.8186774713493 1729932.9132542042 0.05566743829739138 0.12605495592633545 5.45307461623047e-06 5.2633585596769334 0.5139812606371821 NDKSEEEQSSSS(ph)VK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NDKSEEEQSSSSVK 14 1 B4DY08;B2R5W2;G3V4W0;G3V5V7;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 NDKSEEEQS(0.001)S(0.001)S(0.066)S(0.933)VK;NDKSEEEQS(0.007)S(0.005)S(0.462)S(0.526)VK;NDKSEEEQS(0.046)S(0.033)S(0.133)S(0.788)VK 94.387 0.0016317999999999999 20908700.0 49679.0 81945.0 42794.0 50882.0 55614.0 34904.9 57817.0 37162.0 34968.0 40233.2 True False 58088.67349502424 90079.95804436145 43814.37125714875 48031.24650166974 44716.83592843941 33074.42559743535 52340.15520116894 36186.53687639373 35479.340847043386 47527.160674164035 1.2222205717961496 1.8953364090468232 0.9218806811862932 1.0106062685074249 0.9408690797880478 0.6959057753141721 1.1012682949861399 0.7613864654040838 0.7465066362849255 1.0 15.53646459554571 -5.287120785849223 20.812529213235127 0.8944745417027566 1.558777618320021 0.6506423727117845 0.19387325375151762 44.33172578623603 35927.075200972184 0.0477165640321816 0.09947675705819627 5.162727636792068e-06 5.287120785849223 0.6643030766172644 NDKSEEEQSSSS(ph)VK ddPTM_PC-9_Lapatinib_30min_R1 2 NDKSEEEQSSSSVK 14 1 B4DY08;B2R5W2;G3V4W0;G3V5V7;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 NDKSEEEQS(0.003)S(0.001)S(0.034)S(0.962)VK;NDKSEEEQS(0.003)S(0.003)S(0.251)S(0.743)VK 80.545 0.0054123999999999995 27562000.0 39631.2 60206.0 44863.0 54529.0 65633.0 56975.0 60380.0 61405.0 43440.0 50527.0 True False 39066.051820528024 60066.59670604559 41174.537316188056 58539.24456341152 61772.5959794428 54538.31206521194 63506.18095839097 64258.100469973564 38547.329756520616 59260.52462700453 0.659225547975084 1.0136021758854583 0.6948054809731664 0.9878286588224984 1.0423902989089222 0.9203143645535544 1.071643920773724 1.0843322915958742 0.6504723000537682 1.0 15.854783777928082 -5.787551302507999 24.98447035091577 0.9745678210341671 0.8116501494510228 0.2286053910186917 0.14578973683667185 323.7503731150179 309770.3208327108 0.03941589843051213 0.05848398734112026 1.6309802327785165e-06 5.787551302507999 -0.1629176715831443 NDKSEEEQSSSSVK ddPTM_PC-9_Lapatinib_30min_R1 3 NDKSEEEQSSSSVK 14 1 B4DY08;B2R5W2;G3V4W0;G3V5V7;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 0 ;; 143.64 0.00014839 36364000.0 207788.0 171311.0 199456.0 167619.0 165688.0 160430.0 172873.0 150103.0 169149.0 151510.0 False True 204824.90501634765 170914.3399048167 183057.49760242502 179946.26042059224 155942.55759514146 153568.78288059603 181823.51806591472 157077.33335794212 150097.6584020651 177698.30162561472 1.1526553891769031 0.9618231482308094 1.030158960033852 1.012650423636089 0.8775692067315897 0.864210752020263 1.0232147206954811 0.8839551752660074 0.8446769441741752 1.0 17.439070367125787 -1.5228787452804098 0.5107140682455205 0.9150337188337389 8.225347551541061 0.48837056654655897 0.06602462024034964 99.7120513386402 1.0281645295122621 0.03601962957655312 786.1442683936737 0.02999999999999501 1.5228787452804098 7.3103138327073225 NDLAVVDVR ddPTM_PC-9_AZD4547_30min_R2 2 NDLAVVDVR 9 0 P19338 P19338 NCL Nucleolin 0 ; 93.556 0.028406 15737100.0 88433.0 90814.0 107668.0 150990.0 143014.0 109695.0 108916.0 107608.0 99415.0 115766.0 False True 116552.8544793318 120167.84953543798 106240.25197097841 116181.58827224569 123158.97470133244 102835.75430908782 118609.31300175034 90979.6561858429 104669.87394025491 111713.06757642806 1.0433233730654887 1.0756830167001332 0.951010067808715 1.039999982032187 1.1024580863565823 0.9205346924945297 1.0617317702837605 0.8144047796700196 0.9369528221812137 1.0 16.769438428611075 -7.743516618084584 24.99999857495876 0.9067590553098966 1.0259195787712037 0.3608336175628849 0.0670600469360884 226.02440048390096 315276.4956366555 0.030425497312290127 0.017519969187553282 1.8050256673082898e-08 7.743516618084584 0.11916052346130701 NDLAVVDVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NDLAVVDVR 9 0 P19338 P19338 NCL Nucleolin 0 ; 109.83 0.010793 8475400.0 61717.0 72078.0 69154.0 86150.0 85296.0 81849.0 83949.0 71462.0 63779.0 62442.0 False True 72164.46913368639 79233.42749309304 70802.89362800548 81323.29480206827 68582.86110245934 77556.69435307028 75996.74298187274 69586.19822024782 64711.64721698643 73762.24030940003 0.97833890119102 1.0741732783703937 0.9598799240779374 1.1025057598705374 0.9297827833697094 1.0514416865289637 1.0302933135314214 0.9433850968783546 0.8773004581415862 1.0 16.170594853567493 -7.813671274157361 5.778855746431521 0.9307238453980344 1.019122359847603 0.28104027236338447 0.05660295198432513 0.2212990052095787 15.857781156847649 0.02889469098725949 0.013843688667564018 1.5357790036189678e-08 7.813671274157361 0.08839851444956848 NDLAVVDVR ddPTM_PC-9_Lapatinib_30min_R1 2 NDLAVVDVR 9 0 P19338 P19338 NCL Nucleolin 0 ; 147.73 0.0016840999999999998 26923200.0 185687.0 172936.0 169392.0 164985.0 185816.0 180094.0 188642.0 164571.0 150278.0 159993.0 False True 183039.06932917473 172535.57731715648 155465.24363202928 177118.54727382603 174886.6682083118 172391.79943961883 198408.95972760484 172217.56945597296 133352.1091425046 187647.57687272766 0.9754406232131702 0.9194660554246276 0.8284958762748846 0.9438893388639761 0.9319953453325381 0.9186998431455574 1.0573489039092474 0.9177713473634668 0.7106519112311849 1.0 17.517666134998656 -11.122249499700926 3.1098389825219392 1.0047737151093976 0.9155571897517913 0.08489471233832147 0.08623209585928139 114950878.22909743 197137355.19222984 4804948.906919816 0.021231457611008628 7.546585560735168e-12 11.122249499700926 -0.08921652535760627 NDLQDTEIS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 NDLQDTEISPR 11 0 Q9NS91 Q9NS91 RAD18 E3 ubiquitin-protein ligase RAD18 1 NDLQDTEIS(1)PR;NDLQDTEIS(1)PR 157.09 0.00018668 47921000.0 79428.0 88170.0 88527.0 86179.0 88866.0 103168.0 100717.0 120646.0 93630.0 94365.0 True False 104684.45179496738 116669.2282416762 87353.07413748566 66311.76300227737 76528.48983881748 96716.8886508955 109680.61788531767 102002.93286927733 98579.09065056643 91061.3100724706 1.1496040602936075 1.281216228372134 0.9592775907568893 0.7282100702208605 0.8404062030066637 1.0621073711099032 1.2044700191335815 1.1201566591574281 1.0825573514384192 1.0 16.474550594688033 -9.332425741238382 16.02353694825635 1.0001376242191549 1.0435253177125274 0.007524761545413261 0.1578520823136072 0.0 0.0 0.17438373707718138 0.04229426866818575 4.651299005885639e-10 9.332425741238382 0.04338769349337257 NDLQDTEIS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NDLQDTEISPR 11 0 Q9NS91 Q9NS91 RAD18 E3 ubiquitin-protein ligase RAD18 1 NDLQDTEIS(1)PR;NDLQDTEIS(1)PR 167.03 0.00038174 36149000.0 139984.0 210026.0 134336.0 150894.0 173465.0 125761.0 167293.0 137692.0 124779.0 109588.0 True False 163680.52638997335 230875.99326652143 137539.0797121172 142439.89838494832 139475.77847892157 119165.87177041233 151445.79594356572 134077.73089673347 126603.65681632407 129455.43690186941 1.2643773819561357 1.783439914088208 1.062443440026203 1.1003006269479547 1.0774037909635872 0.920516547024156 1.1698681767870869 1.0357056768374113 0.9779709515969803 1.0 16.982096031614965 -5.286119346084418 23.099618594726977 1.0477292480543385 1.523908496066136 0.6763551281604328 0.13302768947516774 131.3073858730058 122899.21204327059 0.03203916384541498 0.06676683892794986 5.174646107986128e-06 5.286119346084418 0.47617924801179745 NDLQDTEIS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 NDLQDTEISPR 11 0 Q9NS91 Q9NS91 RAD18 E3 ubiquitin-protein ligase RAD18 1 NDLQDTEIS(1)PR;NDLQDTEIS(1)PR 170.26 0.00025521 48819000.0 50599.0 93969.0 90094.0 100676.0 117307.0 94104.0 116046.0 121028.0 100950.0 106795.0 True False 49877.448981279835 93751.42055393795 82686.81909289729 108080.04888529086 110407.23289443557 90079.39128713825 122054.29406256102 126651.40271443622 89579.94794937276 125254.37345460757 0.3982092409679852 0.7484882001977651 0.6601511533077379 0.8628844319313073 0.8814640946205952 0.7191716249315893 0.9744513560382283 1.0111535367691966 0.7151841926049528 1.0 16.934501452716525 -4.4421055667468075 0.6537963765569855 0.8963037047188257 1.3136630927882174e-15 0.6250305138075377 0.11003540465039499 3.3191141619940168 0.784831122808721 0.04820928968800813 2.4507245560012936 3.6132202310124103e-05 4.4421055667468075 -0.8963037047188244 NDNGASGQTSESIKKS(ph)EEK ddPTM_PC-9_Lapatinib_30min_R1 1 NDNGASGQTSESIKKSEEK 19 2 Q9NWH9;Q9NWH9-3 Q9NWH9 SLTM SAFB-like transcription modulator 1 NDNGAS(0.001)GQT(0.014)S(0.034)ES(0.046)IKKS(0.905)EEK 45.093999999999994 0.030400999999999997 19927000.0 33907.0 47456.0 28779.0 40250.0 39666.0 35757.0 40740.0 36543.0 28002.0 36034.0 True False 33423.479962217716 47346.11854768795 26412.901710152586 43210.11927006392 37332.92386635649 34227.75646363812 42849.31785764904 38240.921186780295 24848.11988586765 42262.42888771311 0.7908556332864927 1.1202886297302428 0.6249735854114993 1.022423945033276 0.8833596376002476 0.809886165193622 1.0138867780528003 0.9048443781681942 0.5879482211466485 1.0 15.367088063139443 NDQCYDDIR ddPTM_PC-9_AZD4547_30min_R2 2 NDQCYDDIR 9 0 Q9ULV4;Q9ULV4-2;Q9ULV4-3;F8W1H8;F8VUX3;F8VSA4;F8VRE9;F8VTT6;F8VVB7 Q9ULV4 CORO1C Coronin-1C;Coronin 0 ; 114.86 0.0092785 10912000.0 54876.0 48728.0 67273.0 87473.0 80752.0 64812.0 54225.0 76890.0 60624.0 68420.0 False True 72325.42650829212 64478.37307202446 66380.91606460266 67307.45129437806 69540.97868098239 60759.29539432607 59050.91995225584 65008.41725642575 63828.46087365106 66024.63662542732 1.0954308907235735 0.976580506422547 1.0053961590307054 1.019429333268859 1.0532580296579908 0.9202518711163423 0.8943770533303357 0.9846084822129836 0.9667370262976887 1.0 16.01071683591703 -6.761375443024587 24.999999998701707 0.9485567994291889 1.0250939333297417 0.46777470073091376 0.04065392613778313 1.6152636263827167 631571.537785755 0.014036296468124328 0.013190637441651576 1.7323057900684877e-07 6.761375443024587 0.07653713390055283 NDQCYDDIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NDQCYDDIR 9 0 Q9ULV4;Q9ULV4-2;Q9ULV4-3;F8W1H8;F8VUX3;F8VSA4;F8VRE9;F8VTT6;F8VVB7 Q9ULV4 CORO1C Coronin-1C;Coronin 0 ;; 114.86 0.0092785 22091600.0 143126.0 145646.0 158149.0 175929.0 182923.0 157522.0 173628.0 155853.0 141801.0 116690.0 False True 167354.40493264425 160104.772339119 161919.8719434222 166072.2684995139 147080.55127374255 149261.26901836754 157180.69888213818 151762.02388990318 143874.57136386394 137844.97328246856 1.2140769514293834 1.1614843002728594 1.1746519883000734 1.2047756588062348 1.066999744505363 1.0828198189897356 1.1402715321366657 1.1009616112654041 1.043741878559762 1.0 17.072687132770184 -1.522878745280365 0.08849078577320066 0.9019873498538141 1.7598919805693485 0.7464158447998399 0.03412223864200187 86.45107295561307 0.5533990822772114 0.7174890427468509 9.00779518374503 0.029999999999998108 1.522878745280365 0.8579046307155344 NDQCYDDIR ddPTM_PC-9_Lapatinib_30min_R1 3 NDQCYDDIR 9 0 Q9ULV4;Q9ULV4-2;Q9ULV4-3;F8W1H8;F8VUX3;F8VSA4;F8VRE9;F8VTT6;F8VVB7 Q9ULV4 CORO1C Coronin-1C;Coronin 0 ;; 156.83 0.00043668 25602700.0 103562.0 113783.0 120359.0 116030.0 119083.0 127584.0 109777.0 109710.0 124747.0 99580.0 False True 102085.18688905508 113519.54245430694 110463.54761917579 124563.2332647334 112078.77206618586 122127.52973283012 115460.71591701369 114807.52711604576 110696.67921585347 116792.27031799052 0.8740748562478284 0.9719782152125913 0.9458121442319469 1.0665366203224311 0.9596420359072462 1.045681614034159 0.9885989509635235 0.983006210971489 0.9478082660304438 1.0 16.833585269691405 -4.270929699721159 1.2718661514179546 0.9958865761556057 0.6214691851888324 0.4820144619604645 0.03681189231558727 3.7428732829354043 2.158099213533276 0.010451743877403273 2.5153758872906207 5.3588339521035326e-05 4.270929699721159 -0.3744173909667733 NDQCYEDIR ddPTM_PC-9_AZD4547_30min_R2 1 NDQCYEDIR 9 0 Q9BR76;A0A087WW53;F5H390;F5H0D2 Q9BR76 CORO1B Coronin-1B;Coronin 0 99.973 0.018287 5370000.0 22857.0 23470.0 22769.0 34255.0 26382.0 27787.0 22614.0 25529.0 23815.0 27011.0 False True 30125.050544865433 31056.21851913507 22467.068182999687 26358.038984474297 22719.31468646817 26049.4744973483 24626.60219087715 21584.079648059484 25073.812280713897 26065.353111508546 1.1557507168995313 1.1914750736840363 0.8619514221382206 1.0112289241474546 0.8716288856427189 0.9993908153059612 0.944802170357088 0.8280754745858224 0.9619594322565744 1.0 14.669845784036283 -5.253822121670059 24.942652294338156 0.9318656293114601 1.1736129282993346 0.7139854793123733 0.06041560242232076 270.5995725591094 886070.6438765454 0.014688874083719097 0.03730736408526981 5.574140078078435e-06 5.253822121670059 0.2417472989878745 NDQCYEDIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NDQCYEDIR 9 0 Q9BR76;A0A087WW53;F5H390;F5H0D2 Q9BR76 CORO1B Coronin-1B;Coronin 0 ; 126.31 0.0064432000000000005 6783600.0 44581.0 46942.0 34397.0 51205.0 57225.0 53141.0 55196.0 51951.0 37108.0 36060.0 False True 52127.68278511393 51602.09153112974 35217.15493134892 48336.14985884983 46012.172043099716 50354.192410616066 49967.435295565665 50587.34129663446 37650.63429856113 42597.39254919706 1.223729427215763 1.211390849135493 0.8267443809072476 1.1347208588653612 1.0801640497117007 1.1820956494569577 1.1730162882119302 1.187568963011282 0.8838718063570966 1.0 15.378477503158502 -8.262845361864454 24.9975149509171 0.9419358942443093 1.1222141167277788 0.3054849407904149 0.11165377089092988 167.941746347244 2985744.868449003 0.09334561109715639 0.02912770954095951 5.4595222231056514e-09 8.262845361864454 0.18027822248346947 NDQDTWDYTNPNLSGQGDPGS(ph)NPNKR ddPTM_PC-9_AZD4547_30min_R2 1 NDQDTWDYTNPNLSGQGDPGSNPNKR 26 1 P14866;M0QXS5;A0A3B3ITJ4;P14866-2 P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 1 NDQDTWDYTNPNLS(0.105)GQGDPGS(0.895)NPNKR 48.356 0.013491999999999999 5768500.0 10060.0 8354.7 14764.0 8717.5 11211.0 13323.0 9129.8 13170.0 11312.0 10608.0 True False 13258.870739001015 11055.193389936852 14568.219713373777 6707.815059032401 9654.54616594628 12489.910703860493 9942.334513233855 11134.87911649274 11909.929226094298 10236.617148823907 1.2952394864669075 1.0799655031747468 1.4231478526133539 0.6552765392621006 0.9431383459579221 1.2201209171230427 0.9712519642659624 1.0877498840300026 1.1634633837471045 1.0 13.321451412374353 -5.72450256817309 24.99999798891841 1.0143849288035256 1.2475021502114694 0.34489905185709513 0.16347353020223993 220.95321642289298 149546.53918869662 0.045044917891413586 0.07801746878735843 1.8858078178515693e-06 5.72450256817309 0.23311722140794378 NDQDTWDYTNPNLSGQGDPGS(ph)NPNKR ddPTM_PC-9_Lapatinib_30min_R1 2 NDQDTWDYTNPNLSGQGDPGSNPNKR 26 1 P14866;M0QXS5;A0A3B3ITJ4;P14866-2 P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 1 NDQDTWDYTNPNLS(0.009)GQGDPGS(0.991)NPNKR;NDQDTWDYTNPNLS(0.011)GQGDPGS(0.988)NPNKR 62.647 0.00057868 6050500.0 16543.4 29041.0 35174.0 26728.0 28753.0 29315.0 28690.0 28318.0 30346.0 24631.0 True False 16307.488082311995 28973.757348773703 32282.12949556647 28693.666281994225 27061.805070572987 28061.265786602664 30175.42781875188 29633.757659941555 26928.11392245337 28888.435531255527 0.564498830844207 1.0029534938790943 1.1174758654077745 0.9932578817205046 0.9367694917675193 0.9713667518008057 1.044550432165283 1.0258000170303316 0.9321416486302552 1.0 14.81820445564256 -4.761502454751701 9.890062442282437 1.0051887446523455 0.56257587616306 0.8695757043627012 0.05090474365077159 0.025386076449626403 50.719150936916755 0.01332882172860255 0.07537519609972368 1.731799242117453e-05 4.761502454751701 -0.4426128684892855 NDQDTWDYTNPNLSGQGDPGSNPNKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NDQDTWDYTNPNLSGQGDPGSNPNKR 26 1 P14866;M0QXS5;A0A3B3ITJ4;P14866-2 P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 0 141.21 1.5727e-09 5164300.0 8516.1 10345.0 11145.0 11657.0 13640.0 9599.9 12361.0 10369.0 10391.0 9334.0 False True 9957.707529357998 11371.983232276789 11410.739067647872 11003.896082503914 10967.339915559282 9096.464344341895 11190.076594109856 10096.824736863635 10542.948717159337 11026.180312096658 0.9030967431607795 1.0313619866891488 1.034876878906952 0.9979789710523511 0.9946635738876115 0.8249878096372413 1.0148642845821585 0.9157137332305875 0.9561741617441922 1.0 13.428645478802942 -6.574472245847574 24.999998774270573 0.9380805169962155 0.997553030355752 0.14800326479641035 0.058996330204481966 167.42613644407322 81126.287787418 0.01871324927071289 0.01871325188178818 2.6639603351693697e-07 6.574472245847574 0.059472513359536516 NDQDTWDYTNPNLSGQGDPGSNPNKR ddPTM_PC-9_Lapatinib_30min_R1 2 NDQDTWDYTNPNLSGQGDPGSNPNKR 26 1 P14866;M0QXS5;A0A3B3ITJ4;P14866-2 P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 0 ; 135.37 4.7897e-12 18630800.0 64262.0 73470.0 77756.0 64698.0 82774.0 74508.0 79255.0 74709.0 76241.0 71271.0 False True 63345.612095792494 73299.88472898326 71363.20182684006 69456.10674620101 77905.39605994536 71321.46652663113 83358.43610230676 78180.25287861329 67653.93572667788 83590.09738736197 0.7578123973494706 0.8768967499739451 0.8537279421525055 0.8309130975686855 0.931993124722976 0.8532286569319665 0.9972286037186717 0.9352812752008278 0.8093534741700937 1.0 16.351044421181648 -1.5228787452803376 0.19932273495579572 0.9613457925668072 0.16703836918888898 0.4045066009351821 0.058481621771257354 57.23659911793635 0.6900554517021906 0.10766540087775912 14.183178370928763 0.029999999999999995 1.5228787452803376 -0.7943074233779182 NDQEPPPEALDFS(ph)DDEKEK ddPTM_PC-9_AZD4547_30min_R2 1 NDQEPPPEALDFSDDEKEK 19 1 Q96HR8-2;Q96HR8 Q96HR8-2 NAF1 H/ACA ribonucleoprotein complex non-core subunit NAF1 1 NDQEPPPEALDFS(1)DDEKEK 48.867 0.032833999999999995 2062100.0 18579.0 19939.0 14829.0 11166.0 12921.0 16680.0 24282.0 18487.0 17340.0 15304.0 True False 24486.735532793202 26383.89182160351 14632.357770903527 8591.851212980295 11127.142182694839 15636.99696317594 26443.050959533004 15630.258938997833 18256.556999688397 14768.211618175057 1.658070466884269 1.786532621805959 0.990800927642157 0.5817800716240015 0.7534522439400043 1.0588280671663506 1.7905384648598794 1.058371815295622 1.236206351297152 1.0 13.850207510607877 -5.261229704903762 24.998691323160426 1.0590322946174968 1.7223015693621095 0.43797192019800246 0.3006713984025031 18.240235784946858 2174357.2994009657 0.08728177123543181 0.2032328536280826 5.4798704963919005e-06 5.261229704903762 0.6632692747446127 NDQEPPPEALDFS(ph)DDEKEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NDQEPPPEALDFSDDEKEK 19 1 Q96HR8-2;Q96HR8 Q96HR8-2 NAF1 H/ACA ribonucleoprotein complex non-core subunit NAF1 1 NDQEPPPEALDFS(1)DDEKEK;NDQEPPPEALDFS(1)DDEKEK 83.992 0.00065151 17050000.0 202155.0 285443.0 137788.0 209753.0 187001.0 116976.0 222307.0 143677.0 123693.0 147228.0 True False 236375.84875675058 313779.89461293264 141073.38848389962 198001.21943840082 150359.49644791035 110841.57263552105 201248.4715966978 139905.63098836498 125501.77612083458 173919.27094379353 1.3591124633516978 1.8041697904445486 0.8111429384354486 1.1384662456548016 0.864536147328394 0.6373162216816235 1.1571372769940855 0.8044285732636212 0.7216093733591702 1.0 17.408058272260703 -5.26863594625967 24.997199079997767 0.8930640830494424 1.5816411382640727 0.6846835160006959 0.18724720057910446 263.84755685431753 916474.0285749446 0.047483128066640734 0.10219451695330112 5.3872118425305e-06 5.26863594625967 0.6885770552146303 NDQEPPPEALDFS(ph)DDEKEK ddPTM_PC-9_Lapatinib_30min_R1 4 NDQEPPPEALDFSDDEKEK 19 1 Q96HR8-2;Q96HR8 Q96HR8-2 NAF1 H/ACA ribonucleoprotein complex non-core subunit NAF1 1 NDQEPPPEALDFS(1)DDEKEK;NDQEPPPEALDFS(1)DDEKEK;NDQEPPPEALDFS(1)DDEKEK;NDQEPPPEALDFS(1)DDEKEK 86.791 0.00057291 41302100.0 170447.1 402175.0 215805.7 314450.0 344226.0 295638.0 374549.0 378235.0 243000.0 348409.0 True False 168016.49309783042 401243.7884970584 198062.9883800926 337575.7019744504 323979.303454355 282994.25190583814 393941.31453766837 395809.178914753 215630.78109655867 408631.0314241899 0.4111691970926618 0.9819219727356853 0.48469884357482446 0.8261137212166867 0.7928406766495419 0.6925422450652523 0.9640513917033566 0.968622420904381 0.5276906659414164 1.0 18.640439240871814 -2.7613912745901756 0.17292043398426693 0.9430868631188707 9.495273623060823e-31 0.1891715874295663 0.19169535106149735 72.87139146972301 1.1638960399866483 0.48991028902844597 16.44506528711738 0.0017322426425637118 2.7613912745901756 -0.9430868631188707 NDQEPPPEALDFS(ph)DDEKEKEAK ddPTM_PC-9_Lapatinib_30min_R1 1 NDQEPPPEALDFSDDEKEKEAK 22 2 Q96HR8-2;Q96HR8 Q96HR8-2 NAF1 H/ACA ribonucleoprotein complex non-core subunit NAF1 1 NDQEPPPEALDFS(1)DDEKEKEAK 46.956 0.018073 11799000.0 23295.0 16819.0 12817.0 20528.0 18314.0 17848.0 13090.0 12253.0 17492.0 12720.0 True False 22962.80902822019 16780.056638856273 11763.235735050754 22037.69759940053 17236.806526709344 17084.682645720102 13767.736150138091 12822.319111775681 15521.866761074094 14918.635051665398 1.5392030804893777 1.1247715746611202 0.7884927605181681 1.477192620040693 1.1553876388165394 1.1451907353825177 0.9228549463445163 0.8594833955901549 1.0404347788735107 1.0 13.864827924909711 -7.153999676970829 3.4949289638714243 0.9434550963480526 1.1991947806007641 0.278894861319951 0.19740986902734053 0.3595988565660191 8.136813075180708 0.08222790936365322 0.06163574848088078 7.014558201641264e-08 7.153999676970829 0.25573968425271154 NDQNTS(ph)VSHAR ddPTM_PC-9_AZD4547_30min_R2 1 NDQNTSVSHAR 11 0 Q6RI45-3;Q6RI45-4;Q6RI45-2;Q6RI45 Q6RI45-3 BRWD3 Bromodomain and WD repeat-containing protein 3 1 NDQNT(0.249)S(0.735)VS(0.016)HAR 74.96600000000001 0.023472 0.0 5126.3 5678.3 6856.8 9508.1 8577.9 10527.0 7545.0 6855.7 7341.1 10217.0 True False 6756.356766336071 7513.699429791422 6765.874351846468 7316.154443680635 7387.006650331871 9868.7450258605 8216.490383398257 5796.309093313543 7729.135558847314 9859.305939812772 0.6852771186512521 0.7620921265309784 0.6862424589671423 0.7420557276894452 0.7492420557214345 1.0009573783494854 0.8333741171596394 0.5879023461385371 0.7839431706481856 1.0 13.26727037422329 -6.540458495818888 24.998002694327266 0.8216670414499088 0.7229146072236824 0.20681362614904997 0.11172127610767943 503.6636436328211 716193.3998829944 0.03874278673223012 0.03875039556137796 2.8809883637713767e-07 6.540458495818888 -0.09875243422622637 NDQWHWDNIR ddPTM_PC-9_AZD4547_30min_R2 1 NDQWHWDNIR 10 0 E9PF63;O75116;D6REE7;C9JFJ0 E9PF63 ROCK2 Rho-associated protein kinase 2 0 67.385 0.036705 1642100.0 8772.7 8871.6 11076.0 17721.0 13928.0 13154.0 12950.0 13714.0 10608.0 13761.0 False True 11562.236116504397 11739.171206406427 10929.12500307016 13635.697236720756 11994.337614780103 12331.478300576517 14102.524912525829 11594.816416369138 11168.71722333878 13279.231578522415 0.8707006913867625 0.8840248878100105 0.8230239030356791 1.0268438468062326 0.9032403376547423 0.9286289065491729 1.0619985673971521 0.8731541691856916 0.8410665298888873 1.0 13.696884045064882 -5.741209851989959 24.999148389240503 0.9446591538863249 0.8617273372507244 0.2738226822595059 0.06593787785447433 358.17846886905755 442624.62353699666 0.018231370562488473 0.031528700124051304 1.814638613771004e-06 5.741209851989959 -0.08293181663560056 NDRGDQVPNR ddPTM_PC-9_AZD4547_30min_R2 1 NDRGDQVPNR 10 1 F5H1H2;F5H2E6;A0A0C4DGG8;Q8IX12-2;Q8IX12;F5H3E1 F5H1H2 CCAR1 Cell division cycle and apoptosis regulator protein 1 0 106.88 0.0029198 2493400.0 2972.1 3455.5 3486.9 6068.9 4972.7 3945.0 4682.7 4625.2 4020.8 4229.1 False True 3917.165976479613 4572.42279901454 3440.6614277000117 4669.808868570315 4282.326440050045 3698.318526362656 5099.451228408087 3910.4816165225693 4233.331279374112 4081.040496237855 0.9598449170231682 1.1204061325119588 0.843084363135288 1.144269181566618 1.0493222118226337 0.9062195118553675 1.2495468332424202 0.958207011208902 1.0373166557098972 1.0 11.99472131121783 NDRGDQVPNR ddPTM_PC-9_Lapatinib_30min_R1 1 NDRGDQVPNR 10 1 F5H1H2;F5H2E6;A0A0C4DGG8;Q8IX12-2;Q8IX12;F5H3E1 F5H1H2 CCAR1 Cell division cycle and apoptosis regulator protein 1 0 99.788 0.0054942 2753700.0 6758.2 4702.1 5382.0 3635.6 5654.6 5528.1 5515.4 5152.3 5215.7 4056.2 False True 6661.826828697907 4691.212576346161 4939.512735120789 3902.9741520060693 5322.007545371334 5291.676049630509 5800.9604249405365 5391.694667395895 4628.252942244122 4757.3087654532355 1.4003351804858573 0.986106390741956 1.0382997990356833 0.8204164044067943 1.1187013094501759 1.1123255417133648 1.2193785837627613 1.1333497431466844 0.9728720943769101 1.0 12.215929948796198 -6.0687866933789945 0.008452501065151038 3.836033183428277e-07 2.172691949053873 0.04697290415357824 0.14586230761736263 32758.047725508008 71.57158659433883 8864.337273092991 9534.51131263469 8.535192227236792e-07 6.0687866933789945 2.1726915654505548 NDS(ph)GEENVPLDLTR ddPTM_PC-9_AZD4547_30min_R2 2 NDSGEENVPLDLTR 14 0 Q6R327-3;Q6R327;Q6R327-4 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 NDS(1)GEENVPLDLTR;NDS(1)GEENVPLDLTR 148.19 0.00011871 9483400.0 20916.1 26607.0 28302.0 26995.0 32017.0 29043.0 31043.0 35089.0 32692.0 24405.0 True False 27566.984718093343 35207.19242175656 27926.696987801715 20771.719818592446 27571.99220364837 27226.936618796084 33805.76686174049 29666.801315004857 34420.03237795922 23550.58837830388 1.1705433543855572 1.494960204654224 1.185817379133056 0.8820042830746647 1.1707559811562598 1.1561043053972724 1.4354531750418709 1.2597053134492204 1.4615359847938612 1.0 14.523475483542812 -7.224682826577541 24.327252211368585 1.310815820181741 1.177913354591679 0.08029805102834353 0.18060851440696 1007.8925076225553 667071.9477937224 0.07107403422081213 0.05505191173419964 5.960973256790797e-08 7.224682826577541 -0.13290246559006214 NDS(ph)GEENVPLDLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NDSGEENVPLDLTR 14 0 Q6R327-3;Q6R327;Q6R327-4 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 NDS(1)GEENVPLDLTR;NDS(1)GEENVPLDLTR 100.02 0.0020607 8994500.0 17537.8 28667.0 22133.0 19550.4 20655.7 15782.400000000001 23041.0 12675.8 17689.6 17646.6 True False 20506.603152660802 31512.87030639717 22660.734659869937 18455.054471251995 16608.363863183135 14954.743160672684 20858.38967760578 12343.073681120264 17948.276934564718 20845.788889591255 0.9837288126284434 1.5117139712631464 1.0870653435037387 0.8853133152694929 0.7967251300082024 0.7173987628810683 1.0006044764283695 0.5921135317303066 0.8610025281186011 1.0 14.347468350187723 -5.678105160755092 3.009936553888854 0.8147504191666369 1.2573558002873946 0.5051688424425418 0.16614918673910406 0.1741821557944893 3.1590969703257334 0.04437058825130323 0.08286542929884573 2.0984317045171254e-06 5.678105160755092 0.44260538112075765 NDS(ph)GEENVPLDLTR ddPTM_PC-9_Lapatinib_30min_R1 2 NDSGEENVPLDLTR 14 0 Q6R327-3;Q6R327;Q6R327-4 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 NDS(1)GEENVPLDLTR;NDS(1)GEENVPLDLTR 142.72 0.00015444 10862700.0 25180.0 38782.0 32594.0 29970.0 34262.0 31677.0 38877.0 39132.0 38947.0 31067.0 True False 24820.928582553523 38692.20266175896 29914.24713647847 32174.0937769892 32246.77652168373 30322.248552693618 40889.86083337805 40950.21557838945 34560.378729908116 36436.889555824564 0.6812032773688228 1.0618964223737883 0.8209879465876794 0.8830087905197183 0.8850035476348439 0.8321854286227487 1.1222105215850309 1.1238669402790287 0.9484996977296466 1.0 15.153112187923321 -7.256758408626282 24.974948262541297 1.0589665372279236 0.8701705847037724 0.4544315045798232 0.1003025076048033 348.3845986614771 1858784.1795863656 0.03721411480560061 0.027842618074113774 5.536580150465787e-08 7.256758408626282 -0.18879595252415116 NDS(ph)GEENVPLDLTREPSDNLR ddPTM_PC-9_AZD4547_30min_R2 1 NDSGEENVPLDLTREPSDNLR 21 1 Q6R327-3;Q6R327;Q6R327-4 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 NDS(0.879)GEENVPLDLT(0.083)REPS(0.037)DNLR 54.875 0.0085179 4293800.0 5165.9 4736.6 4562.8 9991.1 6753.6 7558.8 4694.8 5304.9 5791.9 7354.1 True False 6808.5487426049 6267.613320738607 4502.294290719441 7687.806255956246 5815.97921562169 7086.147041082394 5112.62810496728 4485.1495994747465 6098.0480096018 7096.635197413828 0.9594052044673351 0.8831809930180243 0.6344266212754148 1.0833030079886103 0.819540395389235 0.9985220944800353 0.7204298886365803 0.6320107311010202 0.8592872311971264 1.0 12.79291943115927 -7.280434804895924 24.84630256257851 0.7722661930716556 0.8888902813704297 0.0756174419863157 0.14358813085627595 1632.6081836087128 2135466.449514028 0.058401043809196834 0.03944659031763444 5.2428229893128826e-08 7.280434804895924 0.11662408829877413 NDS(ph)GEENVPLDLTREPSDNLR ddPTM_PC-9_Lapatinib_30min_R1 1 NDSGEENVPLDLTREPSDNLR 21 1 Q6R327-3;Q6R327;Q6R327-4 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 NDS(0.737)GEENVPLDLT(0.261)REPS(0.002)DNLR 81.639 0.00034613 2861600.0 9562.6 5564.4 6026.0 6289.6 4752.0 8626.3 4277.2 5524.4 8774.9 2997.8 True False 9426.235570433932 5551.515973675716 5530.565541032677 6752.158165490533 4472.496702791463 8257.37325788745 4498.652487499667 5781.083791813729 7786.578358206553 3515.9657356825883 2.680980498407481 1.5789448450350005 1.5729861883762002 1.9204277496122049 1.2720535520017444 2.3485363278958027 1.2794926986472182 1.6442378073094024 2.2146343120419716 1.0 11.779705295643495 -11.556686445268717 2.495562368741583 0.030093906884277304 1.7986341505249355 0.24093590988201852 0.44029886834032916 11854643.208749052 4245010.5544624645 65762869.33958131 0.10617223946514734 2.7753231271797147e-12 11.556686445268717 1.768540243640658 NDS(ph)LPVLR ddPTM_PC-9_AZD4547_30min_R2 1 NDSLPVLR 8 0 Q9GZY8-5 Q9GZY8-5 MFF Mitochondrial fission factor 1 NDS(1)LPVLR 90.434 0.009478100000000001 9065600.0 18487.0 17527.0 23293.0 27211.0 26141.0 32045.0 30441.0 30448.0 22029.0 23890.0 True False 24365.4814465121 23192.259990834278 22984.119600624163 20937.924355759184 22511.773376505356 30041.22108423099 33150.190027969016 25742.96122543441 23193.40796690516 23053.618371550074 1.0569048664647354 1.006013876739423 0.99698534217901 0.9082272473807488 0.976496314534581 1.3031022115514912 1.4379603884168952 1.116655997793526 1.0060636726565926 1.0 14.49270558560546 -6.744118706419236 24.992128040057082 1.1966226942711307 0.9858393480421358 0.33406431472259557 0.12753124332866672 268.5553740905128 387499.8206331756 0.044680106415018246 0.04457819958349956 1.8025249864248142e-07 6.744118706419236 -0.21078334622899486 NDS(ph)LPVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 NDSLPVLR 8 0 Q9GZY8-5 Q9GZY8-5 MFF Mitochondrial fission factor 1 NDS(1)LPVLR;NDS(1)LPVLR;NDS(1)LPVLR;NDS(1)LPVLR;NDS(1)LPVLR 92.943 0.0075956999999999995 20422200.0 104670.0 100290.0 109216.0 110358.0 144079.0 99176.0 112109.0 112559.0 98697.0 85946.0 True False 122388.56367326637 110246.1284064801 111820.12364398659 104174.99904546342 115847.75422975533 93975.03597063023 101489.223921128 109604.44551611837 100140.25690862066 101527.3294518381 1.205474076133602 1.085876374388218 1.1013795423135908 1.026078392960009 1.1410499503457388 0.9256131967423561 0.9996246771099383 1.0795560772443231 0.9863379392454578 1.0 16.631508603398736 -1.522878745414406 0.40942343576226 1.0080478975583378 4.196834168745314 0.5264664582363795 0.05424414164206979 62.4506717545004 0.8155555834454703 0.03776193121124744 161.8156988400535 0.029999999990738886 1.522878745414406 3.188786271186976 NDS(ph)LPVLR ddPTM_PC-9_Lapatinib_30min_R1 2 NDSLPVLR 8 0 Q9GZY8-5 Q9GZY8-5 MFF Mitochondrial fission factor 1 NDS(1)LPVLR;NDS(1)LPVLR 102.05 0.0043989 4988900.0 53497.0 41661.0 29751.0 28800.0 23732.8 27323.0 23906.0 21430.7 33059.0 15694.3 True False 52734.122969851705 41564.53651414423 27304.987622181106 30918.04807398362 22336.88336448005 26154.45898302388 25143.735707043645 22426.44855861676 29335.547293296844 18407.038843659757 2.8648889926157675 2.2580783833387192 1.483399250368085 1.6796861427080239 1.2134968342381651 1.4208944309384504 1.3659848235559258 1.2183626464362831 1.59371355395392 1.0 14.167969937297954 -4.698653349553591 0.9875773486813119 1.3280178435941898 3.9323584901163033 0.8883736284250927 0.17659923498698488 0.6328619356290001 0.44294918911066605 0.05430257687151613 1.8290956182243803 2.001458780915174e-05 4.698653349553591 2.6043406465221137 NDS(ph)PTQIPVSSDVCR ddPTM_PC-9_AZD4547_30min_R2 1 NDSPTQIPVSSDVCR 15 0 Q8TC07-2;Q8TC07-3;Q8TC07 Q8TC07-2 TBC1D15 TBC1 domain family member 15 1 NDS(0.812)PT(0.188)QIPVSSDVCR 202.79 3.3268e-11 57483000.0 24422.0 24682.0 23344.0 37576.0 31833.0 32363.0 24763.0 29332.0 23905.0 28646.0 True False 32187.687990843224 32659.97381718328 23034.443307301364 28913.43374341282 27413.53742757718 30339.33649396061 26966.859027712522 24799.413382305636 25168.569496975262 27643.112259163816 1.1644017391772832 1.1814868568699732 0.8332796644366751 1.0459543582625321 0.9916950439793358 1.0975369274457505 0.9755362845865116 0.89712812181937 0.9104824833401951 1.0 14.754632433339719 -5.233669277146789 24.887364820156776 0.9736674770018067 1.172944390566199 0.5641749286925577 0.07162138992596241 524.9410507569335 470446.53242471046 0.018866936974097446 0.04989298217669392 5.8388957715323536e-06 5.233669277146789 0.19927691356439226 NDS(ph)PTQIPVSSDVCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NDSPTQIPVSSDVCR 15 0 Q8TC07-2;Q8TC07-3;Q8TC07 Q8TC07-2 TBC1D15 TBC1 domain family member 15 1 NDS(0.55)PT(0.45)QIPVSSDVCR 194.67 1.3254000000000002e-09 36801000.0 10992.0 9795.7 6125.9 10871.0 12622.0 13774.0 8728.3 10379.0 9536.9 7870.2 True False 12852.728498103957 10768.152358474013 6271.9646886051205 10261.933114257528 10148.809707785136 13051.667192258812 7901.492236580297 10106.562247459517 9676.359120457799 9297.004959531077 1.3824590342858356 1.1582388527645937 0.6746220654830614 1.1037891405809381 1.0916214148493928 1.4038571829391724 0.8498965280727173 1.087077213731988 1.040803910783958 1.0 13.18255030992004 -7.821719562082175 0.01562987919855858 2.0265290113258175e-06 2.1133676143177516 0.04432511035013664 0.20235013278497618 1916.0376576954811 29.829016395519506 2003.9909600523795 2021.3641692594147 1.507580245008182e-08 7.821719562082175 2.1133655877887403 NDS(ph)PTQIPVSSDVCR ddPTM_PC-9_Lapatinib_30min_R1 1 NDSPTQIPVSSDVCR 15 0 Q8TC07-2;Q8TC07-3;Q8TC07 Q8TC07-2 TBC1D15 TBC1 domain family member 15 1 NDS(0.589)PT(0.411)QIPVSSDVCR 232.01 2.7398e-25 42529000.0 24084.0 30321.0 31251.0 25844.0 23932.0 31288.0 28212.0 27129.0 25964.0 20924.0 True False 23740.55774353531 30250.793587416687 28681.663412348553 27744.653973056673 22524.366812122327 29949.885175890333 29672.679317623846 28389.512379283635 23039.660906959056 24540.68552052253 0.9673958669036324 1.232679240444159 1.1687392916698707 1.130557414537372 0.917837718644248 1.2204176265102407 1.2091218598115203 1.1568345291553679 0.9388352614555849 1.0 14.582887929415989 -8.2606982078402 24.999256108930627 0.9694176170364915 1.1296701286447808 0.27858765352102 0.10024975234419886 84.47805215076676 2849658.1266229833 0.07845892903661682 0.02565334655695033 5.486580961598137e-09 8.2606982078402 0.16025251160828924 NDS(ph)PVPTHDEVVDVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NDSPVPTHDEVVDVK 15 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5 Q8NEV8-2 EXPH5 Exophilin-5 1 NDS(0.999)PVPT(0.001)HDEVVDVK 81.96700000000001 0.016076 0.0 18604.0 21743.0 22169.0 25662.0 25785.0 25717.0 24704.0 20827.0 19977.0 15768.0 True False 21753.28975425093 23901.50134551901 22697.593036400678 24224.241337326534 20732.614349171265 24368.355247808904 22363.858278528416 20280.313318030563 20269.12583222907 18626.61358058068 1.1678606881569709 1.283190916165121 1.218557143423227 1.300517736760358 1.1130640714416393 1.3082547260879627 1.2006400509561237 1.088781556040544 1.08818093769663 1.0 14.185077787882284 -7.814229826770757 2.3999004083070483 1.0489861051494818 1.233441238647276 0.6337440927770316 0.05967143013728234 0.18788218841972446 2.1354932511518747 0.0388221057841798 0.01601567788690128 1.5338050849418775e-08 7.814229826770757 0.1844551334977942 NDS(ph)PVPTHDEVVDVK ddPTM_PC-9_Lapatinib_30min_R1 1 NDSPVPTHDEVVDVK 15 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5 Q8NEV8-2 EXPH5 Exophilin-5 1 NDS(0.928)PVPT(0.072)HDEVVDVK 65.085 0.019624000000000003 3367500.0 16373.0 24628.0 23624.0 24832.0 32989.0 26093.0 19228.0 21238.0 21983.0 20448.0 True False 16139.518017559532 24570.97537913981 21681.72591127715 26658.228117123635 31048.651878869405 24977.063215753842 20223.531756673437 22224.795013130817 19507.043048747524 23982.40955475268 0.6729731631307708 1.024541563392261 0.9040678694847992 1.1115742167717537 1.2946427175294561 1.0414743005172324 0.843265215303008 0.9267123456628006 0.8133896222651131 1.0 14.549688995684988 -14.313437379287015 10.56468763128743 0.9995022761822728 0.9734500353061368 0.0 0.16432822174110712 0.0 0.0 0.0 0.03968872458576419 4.859175901106625e-15 14.313437379287015 -0.026052240876136 NDS(ph)WGSFDLR ddPTM_PC-9_AZD4547_30min_R2 3 NDSWGSFDLR 10 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 NDS(0.956)WGS(0.044)FDLR;NDS(0.992)WGS(0.008)FDLR;NDS(0.667)WGS(0.333)FDLR 133.04 0.00012647 41687200.0 152320.7 137470.9 166669.4 226834.4 205244.6 186320.7 182589.9 203320.9 160486.8 171286.9 True False 200755.51413261914 181905.68003503064 164459.25485614868 174541.23363654473 176749.93006967992 174670.03717486857 198840.04737649453 171902.3267544807 168969.8046077042 165290.1977666749 1.214563941752961 1.100523095094909 0.9949728240285659 1.0559684481890976 1.069330985490027 1.0567477051569285 1.2029754338922076 1.0400031524987317 1.0222614945758821 1.0 17.334641645209075 -1.522878745280644 0.010846458635229407 1.91988149360154e-11 2.3065772449550273 0.20151362800247274 0.06521596074210483 22360.94038556364 18.81629523142506 1702.8718760675092 2346.1728865523114 0.02999999999997883 1.522878745280644 2.3065772449358284 NDS(ph)WGSFDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NDSWGSFDLR 10 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 NDS(0.87)WGS(0.13)FDLR;NDS(0.996)WGS(0.004)FDLR;NDS(0.959)WGS(0.041)FDLR 123.95 0.00042909 31466400.0 116836.0 119871.0 107170.0 131863.0 138604.0 124775.0 141139.0 139782.0 107350.0 96383.0 True False 136614.02718381287 131771.00068015954 109725.33924448841 124475.14361561435 111445.54117713924 118231.57934616625 127769.2921621288 136112.87061127106 108919.79066375256 113856.4749325919 1.1998792977271995 1.1573430563187017 0.963716286750057 1.093263634670836 0.9788247988805201 1.0384264875244436 1.1221961002900704 1.1954776457979746 0.9566411636074095 1.0 16.796856813232537 -5.071845522010363 6.969239849378965 1.0527404524563801 1.1898965669410027 0.3578329493074325 0.0725039351375098 0.25091046751166673 20.720179095732796 0.018671279299085675 0.051039617145533 8.475288254467097e-06 5.071845522010363 0.1371561144846225 NDS(ph)WGSFDLR ddPTM_PC-9_Lapatinib_30min_R1 2 NDSWGSFDLR 10 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 NDS(0.958)WGS(0.042)FDLR;NDS(0.992)WGS(0.008)FDLR 123.95 0.00042909 16511800.0 85691.0 62104.4 63160.0 69388.8 75975.6 65054.9 65242.3 78263.7 75818.8 68947.0 True False 84469.03062619537 61960.601077482934 57967.22860465052 74491.8838262512 71506.86458177677 62272.65357737878 68620.22706097434 81900.11721768379 67279.28833664095 80864.39708389736 1.0445762742602058 0.7662284430711626 0.7168448748156636 0.92119506868969 0.8842811813410036 0.7700874033942339 0.8485839199392087 1.0128081105051938 0.8320013598424314 1.0 16.30321703330324 -8.41294791233113 0.6823938120210724 0.9912467688507496 0.843073020914544 0.1327486044840096 0.10020182950727613 1.3756890987064063 1.48426545504355 0.09905775971360171 0.04088634657174947 3.864133192548246e-09 8.41294791233113 -0.14817374793620564 NDSGEENVPLDLT(ph)REPSDNLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NDSGEENVPLDLTREPSDNLR 21 1 Q6R327-3;Q6R327;Q6R327-4 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 NDS(0.006)GEENVPLDLT(0.972)REPS(0.022)DNLR 70.615 0.0019304000000000003 3467500.0 2250.8 3070.1 2443.3 2905.2 4475.1 4369.7 3457.9 2561.4 3267.4 3241.3 True False 2631.815984673617 3374.879238415945 2501.557538266851 2742.4310627854807 3598.236279774145 4140.545239582787 3130.3426789719656 2494.165964027633 3315.1795436865004 3828.9220318833172 0.6873516782944561 0.8814175922918849 0.6533320651181868 0.7162410307520866 0.939751776038201 1.0813866683898479 0.817551951412355 0.6514016068383709 0.8658258162692009 1.0 11.902722567634038 -6.252181812991993 24.250534005940093 0.8809046844370373 0.7392697591824106 0.28858037361896616 0.12065215151860896 724.5626846712458 1898016.0676765079 0.038918083095637566 0.04948640465474237 5.595233136816833e-07 6.252181812991993 -0.14163492525462673 NDSGEENVPLDLT(ph)REPSDNLR ddPTM_PC-9_Lapatinib_30min_R1 1 NDSGEENVPLDLTREPSDNLR 21 1 Q6R327-3;Q6R327;Q6R327-4 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 NDS(0.182)GEENVPLDLT(0.606)REPS(0.212)DNLR 48.371 0.039864 3166600.0 9742.9 5095.5 7170.6 5809.1 3872.6 6038.5 4291.0 3639.6 6234.6 3785.5 True False 9603.964459370962 5083.701682816584 6581.060947316449 6236.320592589517 3644.821281824538 5780.247431431021 4513.166983975749 3808.7091030130423 5532.393694751461 4439.818631138312 2.163143420322246 1.1450246294212223 1.4822814835634737 1.404634087719616 0.8209392285220563 1.3019107111474597 1.0165205741340453 0.8578524078215641 1.2460855170863199 1.0 12.116285027610953 -1.5228787452803376 0.7461429951101402 1.0761120501965693 168.68417199185052 0.6561263848412917 0.21783539571037044 229.68507191161243 1.0079191826816618 0.08022737314250289 64673.77677724617 0.029999999999999995 1.5228787452803376 167.60805994165395 NDSPT(ph)QIPVSSDVCR ddPTM_PC-9_AZD4547_30min_R2 3 NDSPTQIPVSSDVCR 15 0 Q8TC07-2;Q8TC07-3;Q8TC07 Q8TC07-2 TBC1D15 TBC1 domain family member 15 1 NDS(0.028)PT(0.972)QIPVSSDVCR;NDS(0.004)PT(0.975)QIPVS(0.019)S(0.002)DVCR;NDS(0.013)PT(0.987)QIPVSSDVCR 273.52 2.0186e-74 113269000.0 54119.0 53472.0 58959.0 78587.0 73644.0 62661.0 56535.0 70741.0 50532.0 61866.0 True False 71327.71625487026 70755.77829804814 58177.16513687373 60469.981307046575 63419.80178797147 58742.797764362535 61566.50547719293 59809.603916462635 53203.018356877365 59700.09017054487 1.1947673119271482 1.1851871261152296 0.9744904064747538 1.012895979458362 1.062306633152488 0.9839649755394398 1.0312631907475562 1.0018343983334852 0.8911714907781988 1.0 15.865445490076375 -5.256019092089981 24.570487380445314 0.9987873695540824 1.1899772556368862 0.7743268675614825 0.042114484804868776 155.76181368691744 706070.5407267349 0.010947996144145973 0.027259512562114056 5.546013315031359e-06 5.256019092089981 0.19118988608280374 NDSPT(ph)QIPVSSDVCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NDSPTQIPVSSDVCR 15 0 Q8TC07-2;Q8TC07-3;Q8TC07 Q8TC07-2 TBC1D15 TBC1 domain family member 15 1 NDS(0.217)PT(0.783)QIPVSSDVCR;NDS(0.01)PT(0.99)QIPVSSDVCR;NDS(0.009)PT(0.991)QIPVSSDVCR 230.45 2.0651e-24 87221000.0 55181.0 53603.0 50290.0 63332.0 70595.0 56741.0 65747.0 58890.0 52975.0 46956.0 True False 64522.05342557085 58924.351590114304 51489.10432588704 59783.713365114294 56762.41652044782 53765.402073178266 59518.968192940694 57344.199899112675 53749.659156146314 55468.75109650852 1.1632144612975104 1.0622981485123666 0.9282542568211533 1.0777908675300494 1.0233224184494165 0.9692917365244687 1.073017996914791 1.0338109073222348 0.9690079205610524 1.0 15.759387622460748 -4.85678993836107 3.731559620911454 1.0133311311838478 1.168023989927081 0.5233118911589191 0.04455287391813586 0.18547514888833008 4.327458694736208 0.010951641367622764 0.06823536103979534 1.3906250927881924e-05 4.85678993836107 0.15469285874323324 NDSPT(ph)QIPVSSDVCR ddPTM_PC-9_Lapatinib_30min_R1 3 NDSPTQIPVSSDVCR 15 0 Q8TC07-2;Q8TC07-3;Q8TC07 Q8TC07-2 TBC1D15 TBC1 domain family member 15 1 NDS(0.004)PT(0.996)QIPVSSDVCR;NDS(0.236)PT(0.764)QIPVSSDVCR;NDS(0.075)PT(0.925)QIPVSSDVCR 284.23 1.3746e-88 117865000.0 101074.0 120274.0 117587.0 107163.0 115599.0 116202.0 108758.0 109069.0 125952.0 84998.0 True False 99632.66622529826 119995.5129426123 107919.45075894624 115044.12450528827 108799.69409637828 111232.31134009224 114388.95708301899 114136.74391596064 111765.95942664101 99689.79104728437 0.9994269742028148 1.2036890807173688 1.0825526829297738 1.1540211218892125 1.0913825072095191 1.1157843764296094 1.1474490605438483 1.1449190806491296 1.1211374630490372 1.0 16.60515814937275 -8.70210990622598 18.08735280691471 1.000000000160963 1.121206544736292 0.31961717234025855 0.051355990075603576 417499.56981498224 42132807.30411806 0.04506662943855976 0.011636152589251407 1.9855923630127776e-09 8.70210990622598 0.12120654457532898 NDSPVPT(ph)HDEVVDVK ddPTM_PC-9_Lapatinib_30min_R1 1 NDSPVPTHDEVVDVK 15 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5 Q8NEV8-2 EXPH5 Exophilin-5 1 NDS(0.385)PVPT(0.615)HDEVVDVK 77.42 0.027136 5475700.0 21681.0 37303.0 30172.0 30925.0 32514.0 30417.0 26079.0 24305.0 24023.0 23934.0 True False 21371.824964191535 37216.6271953895 27691.374627288074 33199.327662775795 30601.5904449835 29116.13581549013 27429.24301447299 25434.29902976478 21317.27676659519 28070.96000994964 0.761349984347396 1.3258052871080368 0.9864776486971938 1.1826929912980684 1.0901511894903804 1.0372333473871231 0.9771394709960332 0.9060715779136053 0.7594067591218601 1.0 14.776790783546312 -7.474933580635846 1.7980169617976065 0.8709477028559909 1.0828301665763864 0.2234886221042599 0.14568777916691822 0.46875000732943306 2.961321558706245 0.08305715850951588 0.04306437476854697 3.350166714294167e-08 7.474933580635846 0.21188246372039554 NDSVIVADQT(ph)PTPTR ddPTM_PC-9_AZD4547_30min_R2 2 NDSVIVADQTPTPTR 15 0 B8ZZU6;E9PBF9;P15336-5;P15336;E9PEK8;H7C2N6;P15336-3;P15336-7 B8ZZU6 ATF2 Cyclic AMP-dependent transcription factor ATF-2 1 NDSVIVADQT(0.871)PT(0.128)PT(0.001)R;NDSVIVADQT(0.998)PT(0.002)PTR 141.85 0.00020733 10281600.0 17736.7 13625.5 23152.0 35391.0 32271.0 33925.0 23722.0 34658.0 26611.0 26808.0 True False 23376.601653721602 18029.6764138251 22844.989352751938 27232.151735499356 27790.72868800751 31803.664387034973 25833.21204439673 29302.40246161015 28017.60313256678 25869.460079720135 0.9036370137483943 0.6969483073192979 0.8830872110338641 1.0526756898512728 1.0742678278698796 1.2293903424744006 0.9985988097466394 1.1327025137482944 1.0830378000246956 1.0 14.658962323466236 -5.709697925880066 2.878077112459484 1.0935282508522406 0.7970155311848329 0.6974609142313846 0.07777062344305721 0.1264597683662077 2.1231586724233917 0.02128371407759993 0.03919147742199953 1.951201288600688e-06 5.709697925880066 -0.29651271966740766 NDSVIVADQT(ph)PTPTR ddPTM_PC-9_Lapatinib_30min_R1 2 NDSVIVADQTPTPTR 15 0 B8ZZU6;E9PBF9;P15336-5;P15336;E9PEK8;H7C2N6;P15336-3;P15336-7 B8ZZU6 ATF2 Cyclic AMP-dependent transcription factor ATF-2 1 NDSVIVADQT(0.863)PT(0.136)PT(0.001)R;NDSVIVADQT(0.994)PT(0.005)PT(0.001)R 135.95 6.6221e-05 11068300.0 24277.0 21630.4 25489.0 21854.5 27809.0 36724.0 33911.0 36324.0 29307.0 26460.0 True False 23930.805528143464 21580.31613776781 23393.392810385318 23461.75283447482 26173.329294597585 35153.40012782525 35666.74565220269 38011.745647281496 26006.13704360843 31033.575744266218 0.7711262706349569 0.695386065582694 0.7538091325073133 0.7560119087730207 0.8433874816837175 1.132753776667847 1.149295393676718 1.224858713044196 0.838000018364411 1.0 14.921542315904032 -6.624549152489263 3.703775074610969 1.0879246914157927 0.7457433214038726 0.7046960073193299 0.09972498255953158 0.12192654263991698 3.214617115121445 0.03402655284765344 0.03402742259811837 2.3738367419368545e-07 6.624549152489263 -0.34218137001192017 NDSVIVADQTPT(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 4 NDSVIVADQTPTPTR 15 0 B8ZZU6;E9PBF9;P15336-5;P15336;E9PEK8;H7C2N6;P15336-3;P15336-7 B8ZZU6 ATF2 Cyclic AMP-dependent transcription factor ATF-2 1 NDSVIVADQT(0.044)PT(0.954)PT(0.002)R;NDSVIVADQTPT(0.999)PT(0.001)R;NDSVIVADQTPT(1)PTR;NDSVIVADQT(0.001)PT(0.5)PT(0.5)R 182.09 6.7236000000000005e-21 47657900.0 54961.100000000006 50655.6 65593.0 108923.0 91998.0 78488.0 61589.9 91775.0 77237.0 78103.0 True False 72437.58653810223 67029.03207575188 64723.19396229514 83812.48519357451 79225.6657010725 73580.13295238344 67071.28178455408 77593.28252969804 81319.59013753926 75368.63774270283 0.9611104659393371 0.8893491256214406 0.8587549928028468 1.1120339666970989 1.05117550315208 0.9762699069017928 0.8899096997550271 1.0295168501597416 1.0789579402397065 1.0 16.201676696337223 -5.743397977057828 24.9999846441619 1.015019334607999 0.9016992777927771 0.4282338880909896 0.061581990370079186 262.05738817350334 363130.3452567564 0.0181064607504579 0.03127762960877306 1.8055188334914993e-06 5.743397977057828 -0.11332005681522184 NDSVIVADQTPT(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NDSVIVADQTPTPTR 15 0 B8ZZU6;E9PBF9;P15336-5;P15336;E9PEK8;H7C2N6;P15336-3;P15336-7 B8ZZU6 ATF2 Cyclic AMP-dependent transcription factor ATF-2 1 NDSVIVADQTPT(0.995)PT(0.005)R;NDSVIVADQT(0.002)PT(0.995)PT(0.003)R;NDS(0.001)VIVADQT(0.239)PT(0.758)PT(0.003)R;NDSVIVADQT(0.074)PT(0.923)PT(0.003)R 149.74 7.4218e-05 39710000.0 100025.0 98948.0 102934.0 128267.0 151860.0 111556.0 131807.0 123998.0 113661.0 102526.0 True False 116957.25691619806 108770.90351544958 105388.33693936908 121080.61583722458 122104.12313613122 105705.80697688567 119321.28675995787 120743.18388674087 115323.0770995136 121113.15220463036 0.9656858465593351 0.8980932420260389 0.8701642639216182 0.9997313556222961 1.0081821908972077 0.8727855319815907 0.9852050300726631 0.9969452672054608 0.9521928461135751 1.0 16.885996016513573 -6.579925439195426 0.29603288518025805 0.9987803781943939 0.9023628460707115 0.1586255249836368 0.0475233872750511 5.306568015438315 0.8924296783082033 0.06984326436805757 0.1785805525983046 2.630719601901068e-07 6.579925439195426 -0.09641753212368243 NDSVIVADQTPT(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 4 NDSVIVADQTPTPTR 15 0 B8ZZU6;E9PBF9;P15336-5;P15336;E9PEK8;H7C2N6;P15336-3;P15336-7 B8ZZU6 ATF2 Cyclic AMP-dependent transcription factor ATF-2 1 NDSVIVADQTPT(0.992)PT(0.008)R;NDSVIVADQT(0.008)PT(0.992)PTR;NDSVIVADQT(0.001)PT(0.993)PT(0.006)R;NDSVIVADQT(0.001)PT(0.995)PT(0.004)R 210.39 6.3652e-13 48988000.0 116755.0 95203.0 112535.0 90826.0 107618.0 106288.0 93350.0 91916.0 107543.0 85943.0 True False 115090.05228975507 94982.56330275511 103282.8066976623 97505.64702665394 101288.12082512864 101742.3100094294 98183.20623494196 96186.75291585526 95430.37486200493 100798.13303815074 1.1417875393207435 0.9423047872008252 1.0246499968265397 0.9673358433111986 1.0048610799844124 1.0093670085230775 0.9740577853538313 0.9542513339949448 0.9467474444778239 1.0 16.621109392227567 -4.7527922720427025 24.999713363574017 0.9814140270150735 1.1417878417205989 0.7632797505452198 0.026958032670342743 160.42164329582485 463761.19854789815 0.006735213841911545 0.07738839539393584 1.7668827385790453e-05 4.7527922720427025 0.16037381470552536 NDSWGS(ph)FDLR ddPTM_PC-9_Lapatinib_30min_R1 1 NDSWGSFDLR 10 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 NDS(0.332)WGS(0.668)FDLR 127.56 0.00030887 13435000.0 84026.0 58264.0 57655.0 61214.0 93493.0 75286.0 71544.0 58688.0 72482.0 59686.0 True False 82827.77383151889 58129.093287729505 52914.828454735994 65715.88176391785 87993.92555431026 72066.19328023767 75248.19825251937 61414.85873107739 64318.313890702775 70002.6455734041 1.1832091937820621 0.8303842349326056 0.7558975524610712 0.9387628313991192 1.2570085720837605 1.029478138860763 1.0749336348097709 0.8773219673059123 0.9187983306039372 1.0 16.095121825657156 -4.7343887600536325 24.38193376194532 0.9681612177809096 1.18321070147371 0.19652877431288018 0.13236227770221015 4067.826951976285 3666248.8728960264 0.03651179225387921 3.0207698790937587 1.843364586883675e-05 4.7343887600536325 0.21504948369280052 NDSYTLHK ddPTM_PC-9_AZD4547_30min_R2 1 NDSYTLHK 8 0 P62195-2;P62195;J3QQM1;J3QRW1;J3QLH6;J3KRP2;J3QSA9;J3QSE0 P62195-2 PSMC5 26S protease regulatory subunit 8 0 101.46 0.0045408 0.0 17290.0 17779.0 26139.0 34710.0 30369.0 28057.0 24772.0 34023.0 18634.0 29180.0 False True 22787.86034565878 23525.714062705683 25792.37978108081 26708.145764154244 26152.788557097727 26302.591354665903 26976.6600102772 28765.527120761784 19618.95519793504 28158.417081700747 0.8092734857765809 0.8354771503826574 0.9159740658093474 0.9484959927492165 0.9287733923826843 0.9340933930465543 0.9580318358097077 1.0215605173152853 0.6967350167806403 1.0 14.781278615067018 -5.228597507049985 3.0000139649817466 0.929777244221428 0.8135124537239913 0.20104989440924304 0.08299665266984965 0.3977447126053419 7.099626636757516 0.02118565642649562 0.06655642450094464 5.907483168884342e-06 5.228597507049985 -0.11626479049743677 NDSYTLHK ddPTM_PC-9_Lapatinib_30min_R1 2 NDSYTLHK 8 0 P62195-2;P62195;J3QQM1;J3QRW1;J3QLH6;J3KRP2;J3QSA9;J3QSE0 P62195-2 PSMC5 26S protease regulatory subunit 8 0 ; 128.38 0.0026796 5454300.0 69191.0 71984.0 85481.0 76995.0 91382.0 80632.0 79460.0 72580.0 85160.0 67281.0 False True 68204.32365192467 71817.32547068385 78453.08214620208 82657.46914779051 86007.09042392454 77183.55732237246 83574.04999923392 75952.33176631686 75568.38402544413 78910.4312037029 0.8643258262758569 0.9101119379932344 0.9942042002492649 1.0474846973578795 1.0899330939138072 0.9781160252834938 1.059100156017297 0.9625132014581206 0.9576475869250864 1.0 16.267928402869792 -5.18955779932626 2.5818172986521857 1.015977744073709 0.8695870122782084 0.6097542778242117 0.04056655438596914 0.20599303786466894 2.57274742092194 0.011609656693670674 0.04321339893650776 6.463119719936289e-06 5.18955779932626 -0.14639073179550055 NDVAPTLMS(ph)VPR ddPTM_PC-9_Lapatinib_30min_R1 1 NDVAPTLMSVPR 12 0 A0A087WXI5;P12830-2;P12830 A0A087WXI5 CDH1 Cadherin-1;E-Cad/CTF1;E-Cad/CTF2;E-Cad/CTF3 1 NDVAPT(0.201)LMS(0.799)VPR 106.52 0.0025556 0.0 18438.0 18706.0 11310.0 7082.4 8037.9 9755.5 6044.4 6836.3 10834.0 7274.3 True False 18175.070738884904 18662.687406293204 10380.135457862534 7603.263322193804 7565.126525119422 9338.280006181223 6357.34945652366 7153.939455140143 9613.7608329223 8531.653062604526 2.130310574693769 2.187464406879655 1.2166616928388914 0.8911829004768151 0.8867128643894897 1.0945452115384602 0.7451486142103979 0.8385173896131453 1.1268344788961016 1.0 13.05860958472446 -5.34646158193828 3.1698938834775614 0.9337206511887045 2.18595188225333 0.946861265307132 0.11356427279009638 0.04834449670419663 0.9273531968812682 0.03111670302707287 0.07847851595456419 4.503378167949823e-06 5.34646158193828 1.2522312310646257 up NDVVEALTGS(ph)AASR ddPTM_PC-9_AZD4547_30min_R2 1 NDVVEALTGSAASR 14 0 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 1 NDVVEALT(0.02)GS(0.98)AASR 108.97 0.00063452 1604000.0 11588.0 9771.1 9156.3 17134.0 16452.0 15201.0 11617.0 16557.0 12771.0 15157.0 True False 15272.742954626612 12929.416990725216 9034.881479379856 13184.021017661154 14167.923782191438 14250.479066980657 12650.890494889007 13998.496092009904 13446.048987486765 14626.358043431752 1.0441931552116717 0.8839806158397319 0.6177123144771601 0.9013878218017296 0.9686569780475063 0.9743012597302108 0.8649378373839367 0.9570732543564526 0.9193026006583349 1.0 13.83628296332683 -5.991827206799717 24.99987037647986 0.9417806099789142 0.8367282792552875 0.15345753485692393 0.10249674027342898 350.66629698832065 1072645.1375404017 0.029846228103530468 0.04418480457040592 1.0189967367091927e-06 5.991827206799717 -0.10505233072362674 NEAIQAAHDAVAQEGQCR ddPTM_PC-9_AZD4547_30min_R2 2 NEAIQAAHDAVAQEGQCR 18 0 P09936;D6R956;D6R974 P09936 UCHL1 Ubiquitin carboxyl-terminal hydrolase isozyme L1;Ubiquitin carboxyl-terminal hydrolase 0 ; 109.77 0.00020227 67177000.0 78806.0 72076.0 80994.0 104784.0 89171.0 85464.0 90418.0 98772.0 81235.0 83633.0 False True 103864.6687333711 95373.15747699946 79919.96663946056 80627.66769666191 76791.14585350054 80119.92256959627 98465.02683712439 83509.0569547625 85528.9162554606 80705.03412590416 1.286966418616919 1.1817497942967503 0.990272385174649 0.9990413679880049 0.9515037901316323 0.9927499992702427 1.2200605315836146 1.0347440882620027 1.0597717624656589 1.0 16.300371046633174 -5.047535215432621 3.3844608171554156 1.0340733198999221 1.2768331503459742 0.5918467357211978 0.0698971189992434 0.17734845412716305 3.957297091850048 0.019700308287893934 0.07801646360539387 8.963235032403842e-06 5.047535215432621 0.2427598304460521 NEAIQAAHDAVAQEGQCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NEAIQAAHDAVAQEGQCR 18 0 P09936;D6R956;D6R974 P09936 UCHL1 Ubiquitin carboxyl-terminal hydrolase isozyme L1;Ubiquitin carboxyl-terminal hydrolase 0 ;;; 124.25 3.7792e-05 66830200.0 230243.0 245640.0 204242.0 247527.0 280277.0 198371.0 269291.0 217828.0 208727.0 197882.0 False True 269218.59239346284 270025.51582179527 209111.9038720986 233658.8646833617 225358.73383527936 187968.0755478125 243781.8069819948 212110.24580784392 211779.23750231147 233756.44016695002 1.1517055624272237 1.1551575461576233 0.8945717333937402 0.9995825762767493 0.9640749733967844 0.804119344962495 1.0428880881651201 0.9073985112724754 0.905982471974067 1.0 17.834646587325558 -5.254511644462784 24.83654491449467 0.9383541629889478 1.1534315899191798 0.6398221925238372 0.0640984073124447 287.6030952400351 1031074.9467597435 0.015877313272075776 0.04006518059864149 5.565297121796423e-06 5.254511644462784 0.21507742693023202 NEAIQAAHDAVAQEGQCR ddPTM_PC-9_Lapatinib_30min_R1 2 NEAIQAAHDAVAQEGQCR 18 0 P09936;D6R956;D6R974 P09936 UCHL1 Ubiquitin carboxyl-terminal hydrolase isozyme L1;Ubiquitin carboxyl-terminal hydrolase 0 ; 104.45 0.00030683 78479000.0 107059.0 136145.0 115086.0 133492.0 147764.0 130834.0 125294.0 127360.0 141173.0 103396.0 False True 105532.31902778389 135829.7646172238 105624.07332480683 143309.4469962574 139072.8120352014 125238.53480895009 131781.11025174946 133277.61055053896 125272.61012240525 121267.86083349005 0.8702414498156915 1.12008048697856 0.8709980748306979 1.1817595033941608 1.1468233304301367 1.032743003366012 1.0866944410992365 1.0990348937839285 1.0330239954872629 1.0 16.88783772349509 -4.261026776437056 2.4618133935716995 1.0671210741672559 5.281700026266221e-13 0.3107591643441807 0.08404979326907348 10.321683571819893 11.882750249344292 0.021458192459313016 44.84427210309181 5.4824316193305204e-05 4.261026776437056 -1.0671210741667276 NEDEDS(ph)PNKLYTLVTYVPVTTFK ddPTM_PC-9_Lapatinib_30min_R1 1 NEDEDSPNKLYTLVTYVPVTTFK 23 1 H7C2W9;C9JU56;B7Z4E3;B7Z4C8;P62899-3;P62899;P62899-2 H7C2W9 RPL31 60S ribosomal protein L31 1 NEDEDS(0.974)PNKLY(0.025)T(0.001)LVTYVPVTTFK 92.29 0.00057488 0.0 2440.6 2652.3 2449.0 3737.7 2898.6 2984.5 4740.4 3759.7 4013.2 3664.5 True False 2405.7965964487735 2646.158762306828 2247.652673413382 4012.582926601686 2728.110046866862 2856.8598922093024 4985.834717044663 3934.389387459647 3561.191155130491 4297.903942360678 0.5597604387424627 0.6156858779987977 0.5229648460172031 0.9336139151583094 0.6347536109353837 0.6647100378516454 1.160061924116929 0.915420502697097 0.8285878890942504 1.0 12.069417523726406 -6.435744581950201 0.5678955499886772 0.9790100463376392 0.5362592847404827 0.5030733923018423 0.1432548120891864 0.8722032938429405 0.5991638629302176 0.11577246927469237 0.19331722821543346 3.6665314795707274e-07 6.435744581950201 -0.44275076159715654 NEDEEEEEEEKDEAEDLLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NEDEEEEEEEKDEAEDLLGR 20 1 Q9Y5B9 Q9Y5B9 SUPT16H FACT complex subunit SPT16 0 ;; 159.95 1.1127e-05 7249300.0 48563.8 54503.0 38620.9 54897.0 54572.0 50315.8 66360.0 51508.2 49788.7 50148.0 False True 56784.6921612283 59913.697642221516 39541.768726578906 51821.299068475324 43879.00834837986 47677.15087209643 60073.900395205084 50156.16432744906 50516.76554653366 59239.43542865043 0.9585623453420873 1.0113819824360613 0.6674906409971458 0.8747770584493549 0.7407060521572478 0.8048211554872103 1.014086308563148 0.8466685066210412 0.8527556885206546 1.0 15.854270270882363 -9.887698151142427 10.611655195805275 0.9999999999999997 0.8609906153068547 0.13080706496253913 0.10540622578385456 0.0 0.0 0.10451413048278028 0.025348399961769984 1.2950956625201375e-10 9.887698151142427 -0.13900938469314494 NEDEEEEEEEKDEAEDLLGR ddPTM_PC-9_Lapatinib_30min_R1 1 NEDEEEEEEEKDEAEDLLGR 20 1 Q9Y5B9 Q9Y5B9 SUPT16H FACT complex subunit SPT16 0 142.72 0.00031701 9206400.0 16049.0 18985.0 12934.0 17258.0 17750.0 12451.0 18978.0 14318.0 10060.0 15651.0 False True 15820.138316973847 18941.041398934914 11870.616446683824 18527.210891000323 16705.979897842673 11918.499754698614 19960.58797993284 14983.266550428818 8926.93686350363 18356.254496353376 0.8618391251939033 1.0318576375533315 0.6466796616402339 1.0093132504063347 0.9100974221708168 0.6492882171069443 1.0873998278841785 0.8162485736622016 0.4863158148780864 1.0 14.163984093486892 -8.007508645628329 24.985687025295913 0.7125326589264438 0.8835824994749875 0.08636430777230697 0.18037165940141878 644.0545510990681 2143136.8246246893 0.09835499116561833 0.044037739974719096 9.828593067352027e-09 8.007508645628329 0.17104984054854366 NEDVQLR ddPTM_PC-9_AZD4547_30min_R2 1 NEDVQLR 7 0 P30153;E9PPI5;E9PHZ6;P30154-5;P30154-4;P30154;P30154-2 P30153 PPP2R1A;PPP2R1B Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform;Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform 0 87.696 0.029626999999999997 0.0 26162.0 24080.0 29457.0 42122.0 38518.0 34763.0 32384.0 30405.0 25814.0 26790.0 False True 34480.971796594866 31863.38908993493 29066.380933138134 32411.42367841269 33170.44056907667 32589.26411456147 35266.11326387928 25706.605887392714 27178.47533967452 25852.090254241357 1.3337788727136999 1.2325266071940681 1.1243338796703077 1.2537254573871524 1.2830854388509125 1.2606046085273432 1.364149394383823 0.9943724331217366 1.051306686321643 1.0 14.657993312991506 -7.773961968018983 24.99996441594005 1.0171295599934747 1.2581111068571889 0.7735106978206234 0.06176507686034016 116.64194339843861 232859.23313387996 0.03529466528519277 0.01713758823715377 1.6828214224411422e-08 7.773961968018983 0.2409815468637142 NEEDAAELVALAQAVNAR ddPTM_PC-9_Lapatinib_30min_R1 3 NEEDAAELVALAQAVNAR 18 0 P22314;P22314-2 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 ;; 221.78 1.2230000000000002e-27 8082200.0 31058.1 27019.3 27145.2 25219.8 30841.199999999997 26300.1 27407.0 24813.1 27893.3 26849.1 False True 30615.205798642015 26956.73847091085 24913.426439502207 27074.548222786525 29027.181252132163 25175.306031527514 28826.00035651907 25966.007210675038 24751.662824529398 31489.931160823067 0.9722220617849648 0.8560431057546417 0.7911553160362969 0.8597842937322847 0.9217924645146626 0.7994716121465633 0.9154037272835255 0.824581263073055 0.7860183211617555 1.0 14.942602983194645 -6.739106083206466 24.999099095817563 0.8572755339107389 0.8727763159649294 0.0 0.07255328073793224 1878.4815188057632 2102705.282349662 0.02357364485950891 0.023558093776502007 1.8234502417312177e-07 6.739106083206466 0.015500782054190587 NEEDEGHS(ph)NSSPR ddPTM_PC-9_AZD4547_30min_R2 1 NEEDEGHSNSSPR 13 0 Q14103-3;Q14103;D6RAF8;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 NEEDEGHS(0.722)NS(0.214)S(0.064)PR 105.0 0.00072393 616520000.0 163300.0 227260.0 247380.0 251670.0 243990.0 304350.0 277790.0 319070.0 288240.0 255220.0 True False 215226.0031489924 300717.35068848054 244099.57956477944 193651.36976273987 210116.20007396638 285318.9463874456 302512.7718494628 269765.06299919076 303475.77794637723 246284.8254829225 0.8738906375046491 1.2210145310366773 0.9911271597271243 0.7862903018203521 0.8531431023489343 1.158491782138765 1.228304550458141 1.0953377353648466 1.2322146821320115 1.0 17.90996821524587 -6.780002374297539 24.67986193749318 1.1541681235655175 0.9541571873885171 0.3824007469969657 0.12499619797009352 240.08947681760424 319201.26598030835 0.0464758379494361 0.04106321536248206 1.6595778344640282e-07 6.780002374297539 -0.2000109361770004 NEEDEGHS(ph)NSSPR ddPTM_PC-9_Lapatinib_30min_R1 1 NEEDEGHSNSSPR 13 0 Q14103-3;Q14103;D6RAF8;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 NEEDEGHS(0.333)NS(0.333)S(0.333)PR 57.703 0.038723 1097300.0 2295.4 5031.6 3731.1 1932.1 4645.4 4074.5 4798.4 5536.4 3288.5 3843.1 True False 2262.667175075193 5019.949639340583 3424.343360462502 2074.1930792966564 4372.166705207797 3900.243133123404 5046.837673248485 5793.641355621879 2918.114500559809 4507.374714391135 0.5019922501341978 1.1137191730061626 0.7597201425320302 0.4601776445774916 0.9700029356885626 0.8653026163257999 1.1196845154974477 1.2853693608219336 0.6474088988525538 1.0 12.138071676166936 -6.486225311751252 24.369646229130137 0.9996476282609291 0.7381528837275588 0.2528435722440131 0.2264340642186774 646.6605023368934 429943.02357842115 0.07033067337490975 0.07971845294108008 3.264184425183572e-07 6.486225311751252 -0.2614947445333703 NEEDEGHSNS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 NEEDEGHSNSSPR 13 0 Q14103-3;Q14103;D6RAF8;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 NEEDEGHS(0.014)NS(0.493)S(0.493)PR 112.57 0.00049509 0.0 5150.0 7076.3 6178.2 7317.5 5438.7 8374.6 6665.6 8288.5 6489.3 6758.7 True False 6787.59287334545 9363.575590411398 6096.273031235829 5630.563429248015 4683.630383795561 7850.934938118299 7258.8254870217925 7007.702775782093 6832.311149831479 6522.0799701881715 1.0407098509019996 1.435673225905147 0.9347130147286346 0.8633079408692937 0.7181191284381678 1.2037471134981788 1.1129617422971225 1.0744582721790685 1.0475662949643896 1.0 12.67111641539682 -5.28387502365602 24.81643502176488 0.9941862313477485 1.238191599205595 0.28197817236754363 0.15563660532880483 841.6844396912156 930999.9453322245 0.0429037351701687 0.08941977419443371 5.201456566207976e-06 5.28387502365602 0.24400536785784643 NEEDEGHSNS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 10 NEEDEGHSNSSPR 13 0 Q14103-3;Q14103;D6RAF8;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 NEEDEGHSNS(0.5)S(0.5)PR;NEEDEGHS(0.219)NS(0.39)S(0.39)PR;NEEDEGHS(0.019)NS(0.49)S(0.49)PR;NEEDEGHS(0.182)NS(0.409)S(0.409)PR;NEEDEGHS(0.001)NS(0.5)S(0.5)PR;NEEDEGHS(0.014)NS(0.493)S(0.493)PR;NEEDEGHS(0.082)NS(0.459)S(0.459)PR;NEEDEGHS(0.012)NS(0.494)S(0.494)PR;NEEDEGHSNS(0.618)S(0.381)PR;NEEDEGHS(0.19)NS(0.405)S(0.405)PR 146.84 0.00010621 1861799700.0 299946.6 483799.6 422776.99 340927.9 422331.4 286433.36 349786.6 248521.8 259371.12 258532.6 True False 350721.6351646102 531828.0269678325 432857.59683226346 321826.81506616424 339578.59390132275 271412.29036448814 316652.2810123176 241998.36608061337 263163.9319480497 305402.5138370648 1.1483914482502382 1.7414002926366476 1.4173347540393764 1.0537791946200612 1.1119050384846905 0.888703524258773 1.0368358696001259 0.7923915328664316 0.8616953693067838 1.0 18.220352411769156 -5.857868107077764 2.264711883502198 0.939725281845921 1.4803851274051758 0.6516760243769442 0.15907651248730909 0.17135175439564101 1.79014054157861 0.0477378306457876 0.08276187526159766 1.3871770431919126e-06 5.857868107077764 0.5406598455592548 NEEDEGHSNS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 5 NEEDEGHSNSSPR 13 0 Q14103-3;Q14103;D6RAF8;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 NEEDEGHS(0.265)NS(0.47)S(0.265)PR;NEEDEGHS(0.137)NS(0.432)S(0.432)PR;NEEDEGHS(0.02)NS(0.772)S(0.208)PR;NEEDEGHS(0.219)NS(0.39)S(0.39)PR;NEEDEGHS(0.033)NS(0.483)S(0.483)PR 94.007 0.0021969999999999997 909393450.0 58095.229999999996 99757.7 86334.6 105533.45 122032.0 108345.4 120876.7 129339.4 97803.9 101757.28 True False 57266.78136683958 99526.71717474479 79236.50244919366 113294.73196226872 114854.31768414302 103711.71980746322 127135.10407176462 135348.98070069388 86788.19486127452 119345.8902649472 0.4798387379716859 0.8339350182381315 0.6639231755135353 0.9492973047564106 0.9623650837843439 0.8690011828410998 1.0652658737517096 1.1340900000847949 0.7271988559355099 1.0 16.864789361791026 -4.360189400070684 0.5907479350701177 0.9837651334162674 7.406817194273236e-12 0.5572283161346965 0.1255417601193943 4.343840484518366 0.8026253345379495 0.06091848234244091 3.2484761002901963 4.363255049216954e-05 4.360189400070684 -0.9837651334088605 NEEDEGHSNSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 NEEDEGHSNSSPR 13 0 Q14103-3;Q14103;D6RAF8;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 NEEDEGHSNS(0.017)S(0.983)PR;NEEDEGHS(0.001)NS(0.245)S(0.754)PR;NEEDEGHS(0.001)NS(0.19)S(0.81)PR 128.73 0.00079484 770310000.0 117723.0 128012.4 154033.2 150043.5 134841.8 169730.6 150560.8 190580.6 168314.1 152416.8 True False 155156.46520948465 169389.90488107907 151990.61912449502 115453.28922396654 116121.34360889271 159117.31875048118 163960.41952508278 161130.74737651183 177210.83970595442 147080.73422406326 1.0549067899886793 1.1516797612869538 1.0333822436115394 0.7849654125881955 0.7895075056668747 1.0818365817244382 1.1147647609326246 1.0955258567790718 1.2048541954923264 1.0 17.166248758013225 -6.975058456870686 24.99459039823082 1.1098259134940187 0.9642347954094713 0.2616279442664352 0.11494630151339315 347.45932191918666 348197.1622721576 0.04572459702315647 0.040323948538346234 1.0591111571883239e-07 6.975058456870686 -0.1455911180845474 NEEDEGHSNSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 5 NEEDEGHSNSSPR 13 0 Q14103-3;Q14103;D6RAF8;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 NEEDEGHS(0.008)NS(0.255)S(0.737)PR;NEEDEGHS(0.015)NS(0.168)S(0.816)PR;NEEDEGHS(0.005)NS(0.233)S(0.762)PR;NEEDEGHS(0.004)NS(0.215)S(0.781)PR;NEEDEGHS(0.004)NS(0.237)S(0.759)PR 135.61 5.1719e-05 1268516200.0 97094.40000000001 170485.9 172123.6 178639.6 221388.5 203680.5 196900.2 218129.9 187424.3 190898.0 True False 95709.81605106774 170091.15037317263 157972.26202430986 191777.3521082365 208366.86369653777 194969.55981743583 207094.72891592237 228265.01147635074 166314.60166862456 223894.46494440406 0.427477365618814 0.7596934136599067 0.7055657318886219 0.856552448296823 0.9306476770128195 0.870810092897336 0.924965826945953 1.0195205653388169 0.7428258742793068 1.0 17.772459337169686 -4.456562587571026 0.7256090434115892 0.9191116363028778 7.67315888371087e-15 0.7403606814266321 0.0846531158463017 2.1635078834060217 0.6238774303615475 0.03261145043642467 1.8097914134055575 3.494921395357737e-05 4.456562587571026 -0.9191116363028702 down NEEDEGHSNSSPR ddPTM_PC-9_AZD4547_30min_R2 4 NEEDEGHSNSSPR 13 0 Q14103-3;Q14103;D6RAF8;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 0 ;;; 123.1 0.00014413 6759260.0 16955.57 19764.0 36145.4 40171.5 37968.61 50666.8 37393.4 57728.2 45225.399999999994 42897.600000000006 False True 22347.088562234927 26152.326493915018 35666.08837901517 30910.58131848808 32697.323887414987 47498.59698644141 40721.34015938561 48807.63315206658 47615.92231451601 41395.76808101324 0.5398399304610255 0.6317632865933017 0.8615877910325315 0.7467087277616105 0.7898711729040748 1.1474263961834137 0.9837078050996 1.1790488596937738 1.150260631022226 1.0 15.337195667066245 -6.130044117310241 0.6327078686733411 1.1314141770093369 0.5478476508803097 0.7851895937366489 0.09912356296150208 0.44513919730248835 0.3584276290758156 0.0658379849980916 0.1504481999230756 7.412349399692428e-07 6.130044117310241 -0.5835665261290272 NEEDEGHSNSSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NEEDEGHSNSSPR 13 0 Q14103-3;Q14103;D6RAF8;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 0 ;;; 157.09 6.5309e-05 6342280.0 14405.8 29412.300000000003 27927.799999999996 23741.8 27818.7 20246.899999999998 26741.4 16575.47 19071.9 14964.46 False True 16844.417412480536 32332.15876488105 28593.704668771315 22411.62391795414 22367.82543320888 19185.116921369598 24208.26100102981 16140.381475662174 19350.790457010025 17677.398139399826 0.9528787709395581 1.8290111763007888 1.6175290301937 1.2678123636307401 1.2653347091478873 1.0852907633849878 1.3694470651240147 0.9130518727011125 1.094662817707347 1.0 14.10961832579371 -6.279069425201903 1.5797694886071902 1.1008482229907062 1.490616443238231 0.2968250478883485 0.23712340055976977 0.45923557721253383 2.280263768238467 0.08645293528484196 0.11563594847156361 5.259331853404156e-07 6.279069425201903 0.3897682202475248 NEEDEGHSNSSPR ddPTM_PC-9_Lapatinib_30min_R1 4 NEEDEGHSNSSPR 13 0 Q14103-3;Q14103;D6RAF8;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 0 ;;; 171.26 0.00011328 9703590.0 24061.3 30869.500000000004 35695.4 31529.7 40475.8 40698.6 39478.99999999999 40499.4 38282.4 35775.6 False True 23718.181449697975 30798.023569366447 32760.66200022865 33848.49931799589 38095.093022484536 38958.01575107037 41523.02944776942 42381.14997432857 33970.63298045637 41959.36479200945 0.5652655031187401 0.7339964206329329 0.7807711618758214 0.8066971339004122 0.9079044263734705 0.9284701030195137 0.9896010021504633 1.0100522299231622 0.8096078944199265 1.0 15.356705217179728 -4.110331701141399 0.4567735793909873 0.9663856320182075 3.8294221364047895e-17 0.8162635822163146 0.057483295635193304 3.6093841850926847 0.36731119051070826 0.038396683637473984 2.1392465272196026 7.756544686402895e-05 4.110331701141399 -0.9663856320182075 NEEHHQDTYR ddPTM_PC-9_AZD4547_30min_R2 1 NEEHHQDTYR 10 0 Q9NU19 Q9NU19 TBC1D22B TBC1 domain family member 22B 0 80.916 0.0071507 785630.0 2706.9 2727.4 2520.9 3099.1 3746.7 3248.0 2550.9 2300.4 2608.4 3559.9 False True 3567.6378929822918 3608.978712786066 2487.4712188732 2384.650375617701 3226.535377749614 3044.9020465464896 2777.925158251904 1944.9260379331743 2746.2746988458584 3435.26898454923 1.0385323271710063 1.0505665579662402 0.7240979469325607 0.6941670030332749 0.9392380603270268 0.8863649572250414 0.8086485136232843 0.5661641189324171 0.7994351275541295 1.0 11.746207352404744 -5.252861504874551 24.81717191858277 0.7910332079863218 1.0445494873784746 0.3996015210781364 0.11815360758566523 551.6428413744034 1595981.6131694566 0.031115837098293388 0.07958718796683603 5.586483175010256e-06 5.252861504874551 0.2535162793921528 NEEPS(ph)EEEIDAPK ddPTM_PC-9_Lapatinib_30min_R1 1 NEEPSEEEIDAPK 13 0 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 NEEPS(1)EEEIDAPK 99.055 0.0026031999999999995 5858700.0 15166.0 19464.0 18690.0 20363.0 20672.0 18629.0 24273.0 22790.0 15821.0 21141.0 True False 14949.730058896219 19418.932303864596 17153.380345486356 21860.56294897668 19456.113602715704 17832.281096320014 25529.737171298853 23848.906598985395 14039.072377484175 24795.19368138821 0.6029285453865116 0.7831732453229777 0.6918026358617252 0.8816451780889163 0.7846727818593274 0.7191829725333139 1.0296244304178195 0.9618358664762874 0.5662013597426423 1.0 14.597772874192502 -3.250979968525129 0.35574075481766665 0.8796376976279854 4.0899918307288646e-18 0.231662420203543 0.13516905440531102 30.112225497409398 1.2845537918075154 0.11653361863845398 14.15572776196217 0.0005610738545045479 3.250979968525129 -0.8796376976279854 NEEPS(ph)EEEIDAPKPK ddPTM_PC-9_AZD4547_30min_R2 6 NEEPSEEEIDAPKPK 15 1 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 NEEPS(1)EEEIDAPKPK;NEEPS(1)EEEIDAPKPK;NEEPS(1)EEEIDAPKPK;NEEPS(1)EEEIDAPKPK;NEEPS(1)EEEIDAPKPK;NEEPS(1)EEEIDAPKPK 155.24 0.00091431 2413678800.0 895209.0 860647.0 882484.0 1007821.0 949837.0 958944.0 903635.0 903003.0 889073.0 1016833.0 True False 1179866.840496062 1138834.3118806162 870781.6855551985 775483.4391292328 817968.5279300611 898981.0800872777 984056.7644270486 763464.6352946326 936067.5837014975 981233.9861698761 1.2024316902245962 1.1606144181021627 0.8874353088341198 0.7903144918127379 0.8336121042065601 0.9161740143106312 1.0028767636434923 0.7780658294100892 0.9539697940501634 1.0 19.90423767860301 -5.241897951118037 5.024027568789748 0.8853072698043409 1.188408650858483 0.699233702494771 0.07499400897873475 0.09270994390484999 6.991865204694566 0.019399033146342143 0.05031530171816647 5.7293064025462e-06 5.241897951118037 0.3031013810541421 NEEPS(ph)EEEIDAPKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 10 NEEPSEEEIDAPKPK 15 1 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 NEEPS(1)EEEIDAPKPK;NEEPS(1)EEEIDAPKPK;NEEPS(1)EEEIDAPKPK;NEEPS(1)EEEIDAPKPK;NEEPS(1)EEEIDAPKPK;NEEPS(1)EEEIDAPKPK;NEEPS(1)EEEIDAPKPK;NEEPS(1)EEEIDAPKPK;NEEPS(1)EEEIDAPKPK;NEEPS(1)EEEIDAPKPK 116.51 0.0001112 1647353100.0 840897.0 858291.0 704429.0 962395.0 950799.0 812729.0 990813.0 969907.0 843689.0 683759.0 True False 983244.2536271941 943496.4582323893 721225.2589218601 908475.128276688 764496.7613177315 770108.0605123651 896956.0197750819 944447.9689514131 856026.3555222276 807719.0940667337 1.217309657342282 1.1680997331411824 0.8929159459269543 1.1247414292296398 0.9464884103068743 0.9534355027253308 1.110480148808981 1.1692777549633893 1.0598070069289494 1.0 19.623494118826017 -5.0237530129943 23.04852954804283 1.0378958849762594 1.2050073329233593 0.3798232401443483 0.0828537431571917 256.95399879463776 249337.12216530426 0.021846728438609787 0.05877936529405984 9.46775447624228e-06 5.0237530129943 0.16711144794709987 NEEPS(ph)EEEIDAPKPK ddPTM_PC-9_Lapatinib_30min_R1 5 NEEPSEEEIDAPKPK 15 1 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 NEEPS(1)EEEIDAPKPK;NEEPS(1)EEEIDAPKPK;NEEPS(1)EEEIDAPKPK;NEEPS(1)EEEIDAPKPK;NEEPS(1)EEEIDAPKPK 148.06 8.665599999999999e-06 3668040000.0 655788.0 661675.0 588669.0 637939.0 619676.0 544011.0 589863.0 557713.0 537326.0 504124.0 True False 646436.3428632101 660142.9321906903 540270.907148054 684855.1621621202 583227.8760098901 520744.9176815795 620403.2199181748 583626.3820114054 476806.6875863765 591261.161696994 1.0933177836471728 1.1164997381123376 0.9137601827209628 1.158295532546903 0.9864133039551468 0.8807358768280602 1.0492879629325549 0.9870872971536372 0.8064231484744935 1.0 19.173435988022725 -6.040591403482728 0.5369197971416186 0.9337666603797169 1.1119179307038076 0.2693238620892049 0.0893435821525799 1.9446353021701794 1.0214350908463936 0.06701179152351452 0.18750526579512006 9.107697475786748e-07 6.040591403482728 0.17815127032409073 NEEPVRS(ph)PER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NEEPVRSPER 10 1 Q92922 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 1 NEEPVRS(1)PER 72.321 0.014563999999999999 42565000.0 16096.0 20016.0 19357.0 16471.0 23200.0 15281.0 20705.0 13920.0 12248.0 13200.0 True False 18820.73488950885 22003.056198864408 19818.544291831287 15548.183269702493 18654.12654259349 14479.637459336931 18743.672508781216 13554.614749459139 12427.1038290605 15593.05550885749 1.2069946700836092 1.4110804765856042 1.2709852973058133 0.9971222933741557 1.196309891412699 0.9285952615965427 1.2020525738611043 0.8692725259497451 0.7969639960558981 1.0 13.928616035971976 -6.1809955412658635 0.5362506121088303 0.908025363996444 1.371593808349467 0.5375243345683571 0.1273574848832635 0.9487323072522432 0.5287424510562264 0.09869123599355917 0.23142678330978433 6.59180662763501e-07 6.1809955412658635 0.463568444353023 NEFVS(ph)DEMVS(ph)LS(ph)S(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NEFVSDEMVSLSSK 14 0 C9JR62;B8ZZB3;Q6ZP82;Q6ZP82-2 C9JR62 CCDC141 Coiled-coil domain-containing protein 141 4 NEFVS(1)DEMVS(1)LS(1)S(1)K 44.61600000000001 0.038993 1210300.0 951.29 2088.4 2900.2 3270.6 4013.7 3785.5 3832.3 4545.6 3303.6 3883.1 True False 1112.3246081660589 2295.722550245225 2969.3517670697474 3087.358885428267 3227.2442975865324 3586.9817160081107 3469.276800550698 4426.282816461313 3351.908900202829 4587.075291397314 0.24249102914271609 0.5004763175678991 0.6473300694755382 0.6730560737074356 0.7035516298672853 0.7819757662873341 0.7563156434464994 0.9649466239986175 0.7307289911916338 1.0 12.163358872403318 -4.928858575926831 0.470366602413897 0.8783991769483191 5.081480420227072e-32 0.8344123569882034 0.08375821950256632 1.6992132545615457 0.3226006341420915 0.05713312844820759 0.8205365868968266 1.1779895127083169e-05 4.928858575926831 -0.8783991769483191 down NEGS(ph)ESAPEGQAQQR ddPTM_PC-9_AZD4547_30min_R2 1 NEGSESAPEGQAQQR 15 0 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 NEGS(0.568)ES(0.432)APEGQAQQR 164.01 0.00031789 41970000.0 6497.0 12025.0 10231.0 10614.0 9397.2 13386.0 13670.0 14272.0 12779.0 10458.0 True False 8562.910854004922 15911.84608830845 10095.33025518335 8167.106284665309 8092.560987479293 12548.971303901266 14886.603517701016 12066.590337933521 13454.471851154442 10091.86860316746 0.848496070521305 1.5766996890263034 1.0003430139800673 0.8092759235987238 0.8018892541802753 1.2434735129193628 1.4751087338799345 1.1956745388209147 1.3331992696507746 1.0 13.300905707108607 -6.967560223508263 23.652815325688838 1.2804432205778293 1.0270893424860081 0.20157655490568704 0.23650628180362038 178.71624689748322 130306.21991173914 0.08664093275422913 0.07640930840882126 1.0775558189349393e-07 6.967560223508263 -0.2533538780918212 NEGS(ph)ESAPEGQAQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NEGSESAPEGQAQQR 15 0 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 NEGS(0.5)ES(0.5)APEGQAQQR;NEGS(0.996)ES(0.004)APEGQAQQR 181.86 8.3346e-21 2686300.0 7393.799999999999 10671.2 7928.1 7406.1 7939.4 5943.7 8185.0 6054.0 5308.9 5224.5 True False 8645.424305793404 11730.56621249609 8117.135971486681 6991.160227900161 6383.7315634597735 5632.001908714145 7409.657545731672 5895.088914743223 5386.532619047948 6171.660492880754 1.400826295575758 1.9007147632355583 1.3152272359845634 1.1327843188984117 1.0343620765956993 0.9125586080457398 1.2005938360152824 0.9551868450222486 0.8727849863519744 1.0 12.591442985146676 -5.6129860104695135 2.442892159287037 1.0091526569084068 1.6518273973097015 0.7496142494968958 0.14662487234240318 0.12795673607079766 1.5345904348143065 0.04038033013094998 0.0852693115815702 2.4378893466012503e-06 5.6129860104695135 0.6426747404012947 NEGS(ph)VPT(ph)MMTRKK ddPTM_PC-9_AZD4547_30min_R2 1 NEGSVPTMMTRKK 13 2 Q9Y6X0 Q9Y6X0 SETBP1 SET-binding protein 2 NEGS(1)VPT(0.947)MMT(0.053)RKK 59.294 0.043187 0.0 16882.0 14308.0 26116.0 43838.0 37093.0 19749.0 19431.0 25916.0 17460.0 30049.0 True False 22250.124832585985 18932.781191810158 25769.68477610875 33731.82639034842 31943.277221786222 18514.091908019273 21160.32135716522 21911.277690434785 18382.89995470354 28996.993656203776 0.767325230207983 0.6529222103602307 0.8887019489551614 1.1632870217610178 1.101606518265803 0.6384831519959403 0.7297419038693366 0.7556396345849103 0.6339588225129883 1.0 14.823615712130493 -6.781516966149435 24.99999956572321 0.7349282718791946 0.9125800853527403 0.1899913212223926 0.16670087665412536 431.1092814627256 536800.5210218194 0.06420082270209017 0.056690497169851896 1.6538001761470663e-07 6.781516966149435 0.17765181347354564 NEGSES(ph)APEGQAQQR ddPTM_PC-9_AZD4547_30min_R2 1 NEGSESAPEGQAQQR 15 0 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 NEGS(0.067)ES(0.933)APEGQAQQR 204.71 8.4708e-13 42671000.0 5908.2 7548.2 7944.8 6894.3 6936.2 8766.7 9848.0 11073.0 10701.0 7576.8 True False 7786.884701805743 9988.008036903935 7839.446760959899 5304.925650873196 5973.228357527122 8218.51686313396 10724.452921896094 9361.922282226595 11266.63301347552 7311.53853819843 1.0650131516265575 1.3660610533231203 1.0722020707411255 0.7255553155000308 0.8169591565879829 1.1240475339351779 1.466784708289127 1.2804312298042515 1.5409387442347573 1.0 12.835959303408544 -7.060147800453958 5.8533989299199245 1.3418044828275328 1.012190392421731 0.3354396688820419 0.2069116981708586 0.26542255242024043 18.8336096769456 0.08452754220327208 0.0660429248111878 8.70667231339685e-08 7.060147800453958 -0.3296140904058018 NEGSES(ph)APEGQAQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NEGSESAPEGQAQQR 15 0 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 NEGSES(1)APEGQAQQR;NEGS(0.002)ES(0.998)APEGQAQQR;NEGS(0.001)ES(0.999)APEGQAQQR 152.13 5.0876e-10 95030000.0 23646.100000000002 40540.600000000006 32419.7 29167.699999999997 35663.4 21205.399999999998 35148.3 18943.7 21074.11 22325.8 True False 27648.91769823655 44565.20284450848 33192.70860039692 27533.52833195928 28675.412781859 20093.35149402678 31818.7985723446 18446.447947509267 21382.27899045085 26373.290809064452 1.0483681349592393 1.6897854411551667 1.2585728812040646 1.0439928991529588 1.0872899021006248 0.7618826046206085 1.2064781298133844 0.6994367172855522 0.8107550606882096 1.0 14.686789978727088 -5.90448545469388 1.665263823349481 0.9101245569511855 1.3875315839913767 0.44643886218667006 0.20283865490745145 0.31359382474851116 1.7691040549875694 0.0647816868497147 0.11940059343863478 1.2459899670250041e-06 5.90448545469388 0.4774070270401911 NEGSES(ph)APEGQAQQR ddPTM_PC-9_Lapatinib_30min_R1 2 NEGSESAPEGQAQQR 15 0 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 NEGS(0.181)ES(0.819)APEGQAQQR;NEGS(0.009)ES(0.991)APEGQAQQR 173.09 8.2221e-05 84483000.0 9514.9 11460.9 8878.9 9173.900000000001 12757.1 11147.1 12434.9 14654.6 11229.900000000001 9570.0 True False 9379.215781181043 11434.3629902056 8148.9111155451465 9848.579209233276 12006.752459423597 10670.36451815927 13078.718277567017 15335.506215247526 9965.070405910477 11224.161748776563 0.8356272825632952 1.018727567023163 0.7260151179158996 0.8774445192138088 1.0697237556053873 0.9506602592681224 1.1652289560948816 1.366294121422395 0.8878231291523104 1.0 13.454320084111382 -6.574672431735774 1.4824001830910227 1.1193206529911421 0.8662763509500565 0.32531496539028404 0.14173678030747283 0.4359219395458273 1.9740402108782777 0.05888184790249454 0.06237867879952201 2.662732678823589e-07 6.574672431735774 -0.25304430204108563 NEGSESAPEGQAQQR ddPTM_PC-9_Lapatinib_30min_R1 1 NEGSESAPEGQAQQR 15 0 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 159.12 3.0855e-14 0.0 1804.2 2088.9 847.96 1173.6 768.1 666.92 3001.5 1665.4 1041.6 2158.3 False True 1778.471777150241 2084.0632803916333 778.2440020202573 1259.9104590148322 722.9218681427026 638.397386266453 3156.9029835477068 1742.7805638416091 924.284039465743 2531.3592792460227 0.7025758025466725 0.8232980981713435 0.3074411476872856 0.49772091593023593 0.28558643337188716 0.2521954870256911 1.2471177084305494 0.6884761788380765 0.3651334865989649 1.0 11.305696570301567 -7.231898730562735 24.99904471139113 0.7992218324653743 0.47820458277697564 0.2820916009214465 0.2699583312859245 1061.55944948701 898355.6960052699 0.10786294169857114 0.08353816976867584 5.862748570249204e-08 7.231898730562735 -0.3210172496883986 NEIIQS(ph)PISQVPSVEK ddPTM_PC-9_AZD4547_30min_R2 2 NEIIQSPISQVPSVEK 16 0 Q7Z3T8 Q7Z3T8 ZFYVE16 Zinc finger FYVE domain-containing protein 16 1 NEIIQS(0.999)PIS(0.001)QVPSVEK;NEIIQS(0.975)PIS(0.025)QVPSVEK 195.96 7.7467e-12 25015000.0 114332.0 117258.0 110002.0 163002.0 132046.0 136091.0 121240.0 145660.0 125988.0 119861.0 True False 150687.19774666606 155159.35539483337 108543.3016059701 125424.40725579573 113713.69217987153 127581.20825632973 132030.12512699832 123151.59393381407 132647.46847040043 115664.70287284903 1.302793280957264 1.3414581245706487 0.9384306440080729 1.08437928028636 0.9831321860125102 1.1030262914052578 1.141490202695112 1.064729263768528 1.1468275556478165 1.0 16.819589142170607 -5.246402181067693 24.87736396102757 1.062957267930999 1.322125757395946 0.7272516124508903 0.06469873153976187 384.5531354964151 636197.5011937321 0.01642783876858642 0.04309420583565438 5.6701927052934085e-06 5.246402181067693 0.25916848946494686 NEIIQS(ph)PISQVPSVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NEIIQSPISQVPSVEK 16 0 Q7Z3T8 Q7Z3T8 ZFYVE16 Zinc finger FYVE domain-containing protein 16 1 NEIIQS(0.999)PIS(0.001)QVPSVEK;NEIIQS(0.991)PIS(0.009)QVPSVEK 218.05 3.4844e-22 12018500.0 86272.0 74010.0 59807.0 84343.0 97397.0 101413.0 124907.0 99875.0 108255.0 98710.0 True False 100876.1456503298 81357.22368494987 61233.02569931052 79617.53515369548 78312.75702021476 96094.72375261661 113074.90471163181 97253.3870763096 109838.02457666099 116605.3416120699 0.8651074149409982 0.6977143804922272 0.5251305373558655 0.6827949221963792 0.6716052278355364 0.8241022445807902 0.9697231974828102 0.8340388676177322 0.9419639191322569 1.0 16.831274353375996 -6.929397822916749 3.2107982657059484 0.92183885068467 0.679140895379968 0.6406970307647695 0.08710388005891359 0.17018836977486174 3.5492168187049025 0.034562142685398714 0.029404457706471054 1.1765277554913016e-07 6.929397822916749 -0.24269795530470195 NEIIQS(ph)PISQVPSVEK ddPTM_PC-9_Lapatinib_30min_R1 2 NEIIQSPISQVPSVEK 16 0 Q7Z3T8 Q7Z3T8 ZFYVE16 Zinc finger FYVE domain-containing protein 16 1 NEIIQS(0.999)PIS(0.001)QVPSVEK;NEIIQS(0.962)PIS(0.038)QVPSVEK 221.81 7.4646e-23 20630000.0 111863.0 89745.0 84767.0 73406.0 140272.0 144336.0 167125.0 139512.0 151803.0 138212.0 True False 110267.81310683832 89537.20096641636 77797.78447008267 78804.52211523768 132021.47674536286 138163.08574364937 175777.9147510947 145994.236833596 134705.3475835427 162101.76004408594 0.6802382224403324 0.5523518124791823 0.47993176908705015 0.4861422978615756 0.8144358007553878 0.8523231685212665 1.0843677126225486 0.9006332614395471 0.8309925046273872 1.0 17.306540229654324 -6.466720251515009 2.6685945800818405 0.9369465093256876 0.5448974324012502 0.8153829363495503 0.08608142519470023 0.11936873854388917 1.683369716104141 0.030840865438614102 0.034147227540381145 3.414127600241572e-07 6.466720251515009 -0.39204907692443736 NEIIQSPISQVPS(ph)VEK ddPTM_PC-9_AZD4547_30min_R2 2 NEIIQSPISQVPSVEK 16 0 Q7Z3T8 Q7Z3T8 ZFYVE16 Zinc finger FYVE domain-containing protein 16 1 NEIIQSPIS(0.001)QVPS(0.999)VEK;NEIIQSPISQVPS(1)VEK 191.41 1.4490000000000001e-08 10583100.0 111284.0 126705.0 143481.0 170216.0 162972.0 159648.0 174460.0 159344.0 148486.0 163140.0 True False 146669.997149005 167659.91339867972 141578.34819118012 130975.33101098456 140346.1509014894 149665.1853223686 189986.6020261976 134721.04616085184 156334.666819823 157428.51825595167 0.9316609136252229 1.0649907351989019 0.899318304965547 0.8319669934137424 0.8914912777957468 0.9506866162523284 1.206811854236677 0.8557601103874878 0.9930517580407493 1.0 17.264337383895047 -7.015269021291904 24.964518934528257 1.0128664026220353 0.9248369148836223 0.16343859226515 0.09640176518340088 1401.5202867056466 2291452.7200564225 0.03729880819111618 0.029920109579737158 9.654526494709259e-08 7.015269021291904 -0.08802948773841301 NEIIQSPISQVPS(ph)VEK ddPTM_PC-9_Lapatinib_30min_R1 2 NEIIQSPISQVPSVEK 16 0 Q7Z3T8 Q7Z3T8 ZFYVE16 Zinc finger FYVE domain-containing protein 16 1 NEIIQSPIS(0.081)QVPS(0.918)VEK;NEIIQSPIS(0.005)QVPS(0.995)VEK 142.72 2.7129e-05 11117800.0 56140.0 47101.0 52721.0 47045.0 68383.0 90166.0 90155.0 88597.0 89635.0 86607.0 True False 55339.43330518489 46991.940528376836 48386.48288894523 50504.8462375194 64360.84638615084 86309.81036721189 94822.78476819709 92713.54005925018 79539.36240160515 101576.90455342623 0.5448033049292037 0.46262426222744923 0.4763531936877982 0.4972079672988603 0.6336169296466313 0.8496991589443018 0.9335073281183058 0.9127423253037388 0.7830457400852373 1.0 16.632212889599202 -6.644111631773743 2.1899435409971213 0.901974459795233 0.4906819203734629 0.9257092359979268 0.05411585124503801 0.07553788698030484 0.7401921403919289 0.02011795215276216 0.020011675479814525 2.2692814770376035e-07 6.644111631773743 -0.41129253942177013 NEKPTQSVS(ph)SPEATSGSTGSVEK ddPTM_PC-9_Lapatinib_30min_R1 1 NEKPTQSVSSPEATSGSTGSVEK 23 1 H0YE68;Q9BZ95-3;Q9BZ95-4;Q9BZ95-2;Q9BZ95-5;Q9BZ95 H0YE68 WHSC1L1 Histone-lysine N-methyltransferase NSD3 1 NEKPTQSVS(0.5)S(0.5)PEATSGSTGSVEK 107.7 8.3006e-07 7025300.0 33045.0 39659.0 39252.0 38964.0 47019.0 43892.0 43500.0 44141.0 40910.0 35078.0 True False 32573.772240289196 39567.17202214172 36024.852077101685 41829.54254009367 44253.43486291071 42014.84147724935 45752.21715286534 46191.95200464302 36302.284998601725 41141.18556150302 0.791755798859851 0.9617411720668996 0.8756396196518742 1.016731578567701 1.075648021779905 1.0212355551698984 1.1120782381069008 1.1227666722338245 0.8823830549154327 1.0 15.328295748012602 -5.821144648261985 4.297014621462432 1.0449611493759587 0.8838159475634132 0.47907934256444173 0.07439778603644918 0.17535857419542702 6.493860875501101 0.02072142018851405 0.03265844008108323 1.509577283169624e-06 5.821144648261985 -0.16114520181254555 NEKPTQSVSS(ph)PEATSGSTGSVEK ddPTM_PC-9_AZD4547_30min_R2 2 NEKPTQSVSSPEATSGSTGSVEK 23 1 H0YE68;Q9BZ95-3;Q9BZ95-4;Q9BZ95-2;Q9BZ95-5;Q9BZ95 H0YE68 WHSC1L1 Histone-lysine N-methyltransferase NSD3 1 NEKPTQSVS(0.036)S(0.962)PEAT(0.001)SGSTGSVEK;NEKPTQSVS(0.347)S(0.65)PEAT(0.003)S(0.001)GSTGSVEK 147.17 2.1866999999999997e-06 17370200.0 86193.0 83067.0 87202.0 107743.0 99642.0 107091.0 97955.0 108629.0 95111.0 101309.0 True False 113600.58107422614 109916.78328628017 86045.64450322534 82904.51596275618 85808.42824611696 100394.58284073572 106672.80523602078 91842.88409608876 100138.37328704522 97762.20274605969 1.1620092211844604 1.1243280142919077 0.880152472901327 0.848022176608512 0.8777260110331903 1.0269263582523167 1.0911456804334356 0.9394518690894625 1.0243056158130737 1.0 16.576989171406325 -5.1524352953526735 5.8692073096178285 0.9591269264039399 1.1512152607597583 0.4979697886640986 0.07340778273014686 0.20221447921356087 9.187593441783028 0.021065569310877823 0.0580609372518372 7.039871057236999e-06 5.1524352953526735 0.1920883343558184 NEKPTQSVSS(ph)PEATSGSTGSVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NEKPTQSVSSPEATSGSTGSVEK 23 1 H0YE68;Q9BZ95-3;Q9BZ95-4;Q9BZ95-2;Q9BZ95-5;Q9BZ95 H0YE68 WHSC1L1 Histone-lysine N-methyltransferase NSD3 1 NEKPTQSVS(0.007)S(0.992)PEATSGSTGSVEK;NEKPTQSVS(0.188)S(0.81)PEAT(0.001)SGSTGSVEK 138.46 1.9116000000000002e-11 8377900.0 45417.9 49951.5 43456.5 55529.0 57847.0 48062.2 52158.5 50369.7 41905.2 40198.9 True False 53106.253425585535 54910.35480203712 44492.667769693995 52417.89015744699 46512.29560816405 45541.733623332446 47217.66928516131 49047.54874610862 42517.98427315038 47486.64235568268 1.1183408805324886 1.156332645941771 0.936951225913946 1.1038449458024104 0.9794816668607434 0.9590430353491294 0.9943358161963376 1.0328704307778702 0.8953672477974703 1.0 15.535234130522362 -4.782170093905958 0.6718242602886437 0.9779238805235841 1.2542818948561512 0.4450336822658081 0.05971071687747736 2.9066498674401036 0.9926487961298336 0.025965512361912062 0.6186530008298312 1.651314924671452e-05 4.782170093905958 0.276358014332567 NEKPTQSVSS(ph)PEATSGSTGSVEK ddPTM_PC-9_Lapatinib_30min_R1 1 NEKPTQSVSSPEATSGSTGSVEK 23 1 H0YE68;Q9BZ95-3;Q9BZ95-4;Q9BZ95-2;Q9BZ95-5;Q9BZ95 H0YE68 WHSC1L1 Histone-lysine N-methyltransferase NSD3 1 NEKPTQSVS(0.108)S(0.89)PEAT(0.002)S(0.001)GSTGSVEK 156.8 2.0930999999999999e-07 8320000.0 37006.0 40746.0 43923.0 39130.0 47000.0 46001.0 40153.0 46434.0 44377.0 39092.0 True False 36478.28765393076 40651.65514042677 40311.820487683115 42007.75073385341 44235.552405555274 44033.644463568475 42231.92586986213 48591.493155651035 39378.794949473224 45849.00011318421 0.7956179538022503 0.8866421304733556 0.8792300898202393 0.9162195605171722 0.9648095333890395 0.9604057744959695 0.9211089830881183 1.0598157655716947 0.8588801250247892 1.0 15.484602651047423 -2.8546336102172036 0.4128245619658834 0.9720363556280234 4.507041349207483e-09 0.5115475815581285 0.05010798459376509 19.592895689639708 0.7256478371383925 0.03328782602236105 13.098899351477462 0.0013975468954213427 2.8546336102172036 -0.9720363511209821 NELESYAYSLK ddPTM_PC-9_Lapatinib_30min_R1 2 NELESYAYSLK 11 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 ; 178.71 0.0018410999999999998 21216100.0 101099.0 96089.0 117479.0 89439.0 108913.0 96453.0 104566.0 83888.0 82941.0 90074.0 False True 99657.30972071411 95866.51182419069 107820.3301020544 96016.64241975747 102506.9514711967 92327.93003292472 109979.91583463264 87785.74272820038 73599.31117255005 105643.17088393928 0.9433388726110721 0.9074558347885133 1.0206086129363436 0.9088769450629457 0.9703130889909765 0.8739602310343105 1.041050878295368 0.8309646709169941 0.696678361286666 1.0 16.688839984252866 -7.874283134469725 9.02489199878581 0.8206156621232735 0.9490375427867392 0.25238766401201573 0.08402984407663677 0.3034511905139938 22.748776319864003 0.0426103709582055 0.020426772798317998 1.3357244188321391e-08 7.874283134469725 0.12842188066346572 NELS(ph)NSILSLQPEPEIPPELPPPRPHVR ddPTM_PC-9_AZD4547_30min_R2 1 NELSNSILSLQPEPEIPPELPPPRPHVR 28 1 A0A3B3ITT1;Q6IQ22 A0A3B3ITT1 RAB12 Ras-related protein Rab-12 1 NELS(0.943)NS(0.051)ILS(0.006)LQPEPEIPPELPPPRPHVR 49.626000000000005 0.0076352 6102900.0 7383.3 9053.3 15225.0 18907.0 15447.0 12576.0 10009.0 14910.0 12281.0 11198.0 True False 9731.035817819698 11979.602178069263 15023.10655216173 14548.283260238084 13302.45068462869 11789.620731948473 10899.781609997764 12606.002097715023 12930.148587841593 10805.961428405924 0.9005247596238369 1.10861048851962 1.3902609824860268 1.3463201175227792 1.2310288883375222 1.0910293184053736 1.008682261380761 1.1665784836671065 1.196575489696989 1.0 13.399539816974757 -6.765995172882793 24.944643206118197 1.0977410690752676 1.2097459663126362 0.11748606278189122 0.13768585482942305 262.3552135610642 1436481.132401408 0.052011133109168925 0.04738973027300306 1.71397635798946e-07 6.765995172882793 0.11200489723736862 NELS(ph)NSILSLQPEPEIPPELPPPRPHVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NELSNSILSLQPEPEIPPELPPPRPHVR 28 1 A0A3B3ITT1;Q6IQ22 A0A3B3ITT1 RAB12 Ras-related protein Rab-12 1 NELS(0.766)NS(0.233)ILS(0.001)LQPEPEIPPELPPPRPHVR;NELS(0.756)NS(0.235)ILS(0.009)LQPEPEIPPELPPPRPHVR 72.842 2.9361999999999998e-05 9027000.0 37188.0 29159.0 31546.0 44804.0 49019.0 33315.0 37379.0 38394.0 33133.0 30317.0 True False 43483.193903519845 32053.71281488243 32298.176278871237 42293.777136527875 39414.0788358358 31567.902752294332 33838.19051947513 37386.19818180563 33617.507443522336 35813.23211076003 1.2141655846375112 0.895024294812306 0.9018503601959819 1.1809539280265289 1.1005451480597837 0.8814591951562453 0.9448516239702504 1.0439213658845665 0.9386895698090877 1.0 15.12820510596397 -6.748942747417882 24.99795717736994 0.9634711266970298 1.047524796860836 0.1736593596527375 0.10409345925302688 506.8792549520574 1013947.1613433601 0.03594253718284575 0.03570618306384793 1.7826137520440059e-07 6.748942747417882 0.08405367016380627 NELS(ph)NSILSLQPEPEIPPELPPPRPHVR ddPTM_PC-9_Lapatinib_30min_R1 1 NELSNSILSLQPEPEIPPELPPPRPHVR 28 1 A0A3B3ITT1;Q6IQ22 A0A3B3ITT1 RAB12 Ras-related protein Rab-12 1 NELS(0.668)NS(0.321)ILS(0.011)LQPEPEIPPELPPPRPHVR 85.404 1.9049e-07 4750000.0 11584.0 11182.0 11960.0 8135.1 9577.6 9149.6 8349.1 5367.6 11997.0 7269.2 True False 11418.810035754574 11156.108766020026 10976.694966935085 8733.382391898056 9014.264398286085 8758.292936759331 8781.375545539953 5616.998291387189 10645.77152598936 8525.671534399844 1.3393443542460364 1.3085313832472611 1.2874874339980984 1.0243629908400915 1.0573084315897978 1.027284818729046 1.02999224285247 0.6588335322001814 1.2486724926048605 1.0 13.05759775882146 -5.7627630621196655 3.093435688055649 0.9913351476083423 1.3229324665941358 0.5140776149297768 0.13594927043250363 0.19106252832778792 3.7642584798883933 0.0383139490059112 0.06665182470826622 1.7267797136237687e-06 5.7627630621196655 0.3315973189857935 NELSNS(ph)ILSLQPEPEIPPELPPPRPHVR ddPTM_PC-9_AZD4547_30min_R2 1 NELSNSILSLQPEPEIPPELPPPRPHVR 28 1 A0A3B3ITT1;Q6IQ22 A0A3B3ITT1 RAB12 Ras-related protein Rab-12 1 NELS(0.442)NS(0.548)ILS(0.01)LQPEPEIPPELPPPRPHVR 72.37 3.9812e-05 2483100.0 1138.5 1078.3 3595.4 1711.7 3318.3 886.52 1805.9 1400.9 1288.8 1560.9 True False 1500.5193177288916 1426.8393876942205 3547.7226468073713 1317.0940105013776 2857.611323027343 831.0857642562792 1966.6216015081384 1184.4230944794758 1356.923336862653 1506.2533661009843 0.9961931714138269 0.9472771446066003 2.3553292737136498 0.8744173059747209 1.897165103387898 0.5517569506965406 1.305637979484714 0.7863372266150794 0.9008599531798028 1.0 10.556748750072252 -6.769980084989308 24.999889136378993 0.9203595525157886 1.4104538980767383 0.23177513317574028 0.4595813614359695 297.371312154837 870443.7949980819 0.15613388982490145 0.13985603309297964 1.698321528919665e-07 6.769980084989308 0.49009434556094966 NELSNS(ph)ILSLQPEPEIPPELPPPRPHVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NELSNSILSLQPEPEIPPELPPPRPHVR 28 1 A0A3B3ITT1;Q6IQ22 A0A3B3ITT1 RAB12 Ras-related protein Rab-12 1 NELS(0.303)NS(0.673)ILS(0.023)LQPEPEIPPELPPPRPHVR 59.567 0.00077085 4460900.0 5684.1 8296.6 8141.5 9056.5 11209.0 9478.6 8916.6 7062.5 7937.2 6387.6 True False 6646.305863907634 9120.231617680778 8335.624236810689 8549.093666569159 9012.676914479758 8981.525529878349 8071.955097406356 6877.116858337297 8053.266534292864 7545.621315786221 0.8808162490215186 1.2086786807867378 1.1046968682846168 1.1329873722503898 1.1944247580546223 1.1902963525466177 1.069753537792705 0.9114049818468436 1.067276795012837 1.0 12.881423983598077 -7.528960681187055 22.707245489479618 0.9917202530690149 1.1265224425896492 0.2611523358345903 0.09409838262932975 64.48262925439685 240733.8118507163 0.042521099097906905 0.02467045739664775 2.958280282074706e-08 7.528960681187055 0.13480218952063427 NELSNS(ph)ILSLQPEPEIPPELPPPRPHVR ddPTM_PC-9_Lapatinib_30min_R1 1 NELSNSILSLQPEPEIPPELPPPRPHVR 28 1 A0A3B3ITT1;Q6IQ22 A0A3B3ITT1 RAB12 Ras-related protein Rab-12 1 NELS(0.174)NS(0.822)ILS(0.004)LQPEPEIPPELPPPRPHVR 66.67699999999999 0.00011037 5527500.0 7578.5 6034.3 9105.1 5508.7 7014.3 7397.9 6329.3 5237.6 11102.0 4564.1 True False 7470.429200273314 6020.32794909629 8356.513824702399 5913.828174484498 6601.732664644389 7081.509062347194 6657.000184497249 5480.958016798851 9851.575850757186 5352.998603719026 1.395559713967269 1.1246645842413696 1.561090230603958 1.1047692353918854 1.2332774867637362 1.3229050830365015 1.2436020775107735 1.0239042492914017 1.8403845358586026 1.0 12.38613156100117 -5.812869665594186 24.999995538000604 1.2554261019046165 1.3368729575718634 0.0371295618788976 0.24241553904619484 492.73918512693564 239515.5319463262 0.06488590854856224 0.09624154987694146 1.5386163191045393e-06 5.812869665594186 0.08144685566724696 NEMGIPQQTTS(ph)PENAGPQNTK ddPTM_PC-9_AZD4547_30min_R2 1 NEMGIPQQTTSPENAGPQNTK 21 0 Q15398-1;Q15398;Q15398-3 Q15398-1 DLGAP5 Disks large-associated protein 5 1 NEMGIPQQT(0.035)T(0.211)S(0.754)PENAGPQNTK 85.537 0.00031785 7772700.0 51592.0 46547.0 53539.0 70448.0 63140.0 59667.0 46795.0 62120.0 52927.0 58514.0 True False 67997.1828197355 61592.407473803985 52829.037878238836 54207.302010750165 54374.10087573348 55936.01305766301 50959.664346073056 52520.78137559068 55724.613167387964 56465.44267027548 1.2042265074728717 1.0907982752117418 0.9355994636707078 0.9600084484821715 0.9629624475494828 0.9906238295924815 0.9024929573942617 0.9301402573301467 0.9868799487287558 1.0 15.785080575552309 -5.0072251703261195 2.5704743089534046 0.9551843099753825 1.209664081575072 0.8768661284196873 0.029689878031936505 0.10247470499623348 1.1891470586231525 0.00796929165359796 0.045769795796061816 9.835010539838374e-06 5.0072251703261195 0.2544797715996896 NEMGIPQQTTS(ph)PENAGPQNTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NEMGIPQQTTSPENAGPQNTK 21 0 Q15398-1;Q15398;Q15398-3 Q15398-1 DLGAP5 Disks large-associated protein 5 1 NEMGIPQQT(0.045)T(0.169)S(0.785)PENAGPQNT(0.001)K 64.502 0.0031921 5698700.0 60339.0 63006.0 50677.0 63075.0 63634.0 57714.0 55753.0 59953.0 53504.0 42908.0 True False 70553.20095042718 69260.81928785225 51885.33187359274 59541.112241909075 51165.37450049113 54687.37624030961 50471.6722232349 58379.29727545428 54286.39478037664 50686.880740458895 1.3919420552172734 1.366444694880729 1.0236442076455738 1.1746848764828928 1.0094401895133842 1.078925659685692 0.995754157405622 1.15176346270713 1.07101470809279 1.0 15.629324763071686 -5.254723320083647 24.409800998506498 1.0687946453435528 1.3791934479341332 0.8236659881783945 0.05844512149977129 137.45279529133998 499573.09792718105 0.014242114596752604 0.035868001998749344 5.562585250633432e-06 5.254723320083647 0.3103988025905804 NEMGIPQQTTS(ph)PENAGPQNTK ddPTM_PC-9_Lapatinib_30min_R1 1 NEMGIPQQTTSPENAGPQNTK 21 0 Q15398-1;Q15398;Q15398-3 Q15398-1 DLGAP5 Disks large-associated protein 5 1 NEMGIPQQT(0.001)T(0.252)S(0.747)PENAGPQNTK 119.45 7.5463e-05 0.0 33968.0 22319.0 26781.0 23206.0 21303.0 28390.0 20881.0 19921.0 22647.0 17796.0 True False 33483.61009103171 22267.321726775266 24579.169557649544 24912.64665294666 20049.999423309437 27175.825880322376 21962.116008482324 20846.60238518594 20096.25637651755 20872.01488832054 1.6042346783572057 1.0668506057474836 1.1776136462706068 1.1935908816779905 0.9606163818198941 1.3020221586526988 1.0522278814956085 0.9987824604730029 0.9628326006878672 1.0 14.34928225791378 -3.0642745601047094 1.6582624972096371 1.0822262579251307 139.53948328963062 0.6648138400297398 0.11008566638604085 224.45712738317877 3.029691370540853 0.030405781145006618 116860.81603762235 0.000862433146870219 3.0642745601047094 138.4572570317055 NENLQESEILS(ph)QPK ddPTM_PC-9_AZD4547_30min_R2 1 NENLQESEILSQPK 14 0 Q86YC2;H3BN63 Q86YC2 PALB2 Partner and localizer of BRCA2 1 NENLQESEILS(1)QPK 129.88 0.00042364 0.0 4214.2 6040.1 8088.1 7570.4 5307.4 6041.0 6058.3 7936.0 4826.3 5444.6 True False 5554.227939194637 7992.444204406809 7980.846509329337 5825.161241514063 4570.559122392586 5663.255315020733 6597.476963517778 6709.673551137921 5081.408364913267 5253.986211207262 1.0571455112209716 1.5212152988445515 1.5190078901055006 1.1087127006706696 0.8699221769259957 1.0778968743656883 1.2557088462555763 1.277063410791893 0.9671529693157798 1.0 12.359196698866215 -5.823264209335658 8.964436819312914 1.0888986174541733 1.3809316013099782 0.3807628303528674 0.16671168119937596 0.3192938804648687 42.859223340879126 0.04888651960193005 0.07278574417694955 1.5022277860184249e-06 5.823264209335658 0.2920329838558049 NENLQESEILS(ph)QPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NENLQESEILSQPK 14 0 Q86YC2;H3BN63 Q86YC2 PALB2 Partner and localizer of BRCA2 1 NENLQESEILS(1)QPK;NENLQESEILS(1)QPK 167.71 9.382e-19 0.0 17084.800000000003 17224.9 16857.2 22569.0 25517.0 15723.5 18646.5 16889.9 16113.0 15331.900000000001 True False 19976.919199818658 18934.874236601692 17259.139579287 21304.53209968522 20517.127025317175 14898.9319803602 16880.168531030624 16446.558021328296 16348.62214219887 18111.45210274637 1.102999311512378 1.0454641698072602 0.9529406853396294 1.1763017111396972 1.1328261758871347 0.8226249279096162 0.9320162974933943 0.9080750636683839 0.9026676629490029 1.0 14.144614599909692 -6.754976465264844 24.999887508764996 0.9085151973513745 1.0781279379502382 0.605999281176901 0.06805930488478626 110.2255601227562 426374.9094858735 0.023385107783705273 0.022855538427358754 1.7580188797044495e-07 6.754976465264844 0.16961274059886366 NENLQESEILS(ph)QPK ddPTM_PC-9_Lapatinib_30min_R1 2 NENLQESEILSQPK 14 0 Q86YC2;H3BN63 Q86YC2 PALB2 Partner and localizer of BRCA2 1 NENLQESEILS(1)QPK;NENLQESEILS(1)QPK 183.75 7.0824e-06 4244500.0 38942.0 40460.0 40719.0 44286.0 42533.0 34922.9 37955.0 42503.0 40471.0 31612.8 True False 38386.67993891184 40366.317355855 37371.24099988544 47542.94017376523 40031.292563095354 33429.32897625605 39920.124184758686 44477.844544830026 35912.72980147666 37077.030358591815 1.0353223968493082 1.0887149527740148 1.00793511881745 1.2822747591690056 1.079679040525395 0.9016182971759904 1.076680731942925 1.1996064440614842 0.9685977936783344 1.0 15.178238077167135 -6.530341119415602 24.989332132993017 1.0387274733749303 1.1063341084490192 0.10898311671321526 0.09926226875248614 482.9493237112849 1617242.2287462433 0.033732630340348395 0.03379364650499677 2.9488920903756285e-07 6.530341119415602 0.06760663507408893 NENPVDYTVQIPPSTT(ph)YAITPMKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NENPVDYTVQIPPSTTYAITPMKR 24 1 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 NENPVDYTVQIPPS(0.093)T(0.093)T(0.283)Y(0.248)AIT(0.283)PMKR 41.853 0.039454 5768500.0 7440.8 6535.6 8853.8 7932.5 12467.0 7442.1 8912.3 6723.2 9979.9 4801.3 True False 8700.380477501087 7184.411175724327 9064.908170223485 7488.067742511993 10024.180845108329 7051.823174931702 8068.062424535661 6546.7231238192335 10125.837157384138 5671.73768293011 1.5339885170793603 1.2667037118706705 1.598259418362312 1.3202422539830048 1.7673914777965678 1.2433267490764166 1.4225027452905 1.1542711404870707 1.7853147877165167 1.0 12.469575094339795 NENPVDYTVQIPPSTTYAIT(ph)PMK ddPTM_PC-9_AZD4547_30min_R2 1 NENPVDYTVQIPPSTTYAITPMK 23 0 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 NENPVDYTVQIPPS(0.136)T(0.136)T(0.136)Y(0.121)AIT(0.471)PMK 53.998000000000005 0.011436 3692600.0 7066.2 8053.8 9079.8 12425.0 13331.0 11256.0 8894.8 12904.0 7598.2 11498.0 True False 9313.104613909443 10657.03334935705 8959.395919364075 9560.608214336395 11480.220759809996 10552.160540618012 9686.419968489177 10909.983304420835 7999.825339967264 11095.458519718826 0.8393618521810714 0.9604860700815017 0.8074831611006841 0.86166860047697 1.0346774528882579 0.95103420213457 0.8730076320211996 0.983283681790314 0.7209999772204088 1.0 13.43768166767527 NENPVDYTVQIPPSTTYAIT(ph)PMKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NENPVDYTVQIPPSTTYAITPMKR 24 1 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 NENPVDYTVQIPPS(0.176)T(0.127)T(0.127)Y(0.108)AIT(0.463)PMKR 61.256 0.0016334 6989400.0 20259.0 30016.0 23477.0 25352.0 29937.0 22783.0 30831.0 17979.0 17145.0 23474.0 True False 23688.44856651093 32995.79011116673 24036.78071701832 23931.60963229296 24071.059754552643 21588.2193728207 27910.464482889794 17507.070300325126 17395.71318984669 27729.650379918232 0.8542642349240028 1.189910065907727 0.8668259566094536 0.8630332263267262 0.8680621437616417 0.7785247587706642 1.006520605218395 0.631348396408334 0.6273325826871816 1.0 14.75914180630052 -5.472570570780688 10.469413334854709 0.8206806990318539 1.0239448203155337 0.22983901243294969 0.1421530267734153 0.9946673341815979 203.5341456738014 0.03696199121523985 0.07668693175615082 3.3684447567436657e-06 5.472570570780688 0.20326412128367977 NENPVDYTVQIPPSTTYAIT(ph)PMKR ddPTM_PC-9_Lapatinib_30min_R1 1 NENPVDYTVQIPPSTTYAITPMKR 24 1 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 NENPVDYTVQIPPS(0.019)T(0.222)T(0.222)Y(0.174)AIT(0.363)PMKR 94.271 3.0602999999999997e-06 3848500.0 11642.0 16293.0 15169.0 13030.0 18272.0 15561.0 15161.0 16127.0 14486.0 13765.0 True False 11475.982945118674 16255.27455953894 13921.86337403331 13988.269666805774 17197.27688413418 14895.492304462705 15945.962396657264 16876.319294508 12854.434135657406 16144.261909290422 0.7108397404352486 1.0068762914571296 0.8623412734664442 0.8664545796767609 1.0652253401710354 0.9226493219792787 0.987717028270023 1.0453447416382848 0.7962230920114197 1.0 13.978733864220917 -4.753063483694411 24.99744176790232 0.9502571041550354 0.710839294599852 0.42940710779805824 0.0828151128768634 302.5950821463136 903010.6929719846 0.019956623703626223 0.22302788037228127 1.7657796861343092e-05 4.753063483694411 -0.23941780955518344 NENTEGS(ph)PQEDGVELEGLK ddPTM_PC-9_AZD4547_30min_R2 2 NENTEGSPQEDGVELEGLK 19 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 NENTEGS(1)PQEDGVELEGLK;NENT(0.002)EGS(0.998)PQEDGVELEGLK 123.0 2.9124e-05 6424600.0 31945.0 31853.0 34116.0 35235.0 34770.0 43558.0 33958.0 40418.0 35945.0 38137.0 True False 42102.84550272239 42148.859330635256 33663.599549001585 27112.11512532337 29942.78567388743 40834.311374221696 36980.196214637246 34172.32681324251 37844.97931682811 36801.83523799939 1.1440420085150942 1.145292321919719 0.9147261089371584 0.736705518895672 0.8136220783622847 1.1095726914199815 1.0048465239704594 0.9285495299962159 1.0283448929131564 1.0 15.167490092101897 -5.257911140018345 24.171556699527397 0.9357999388200778 1.1446672066627843 0.38893606187234364 0.10134796222767767 203.33406331835397 1392991.5851791895 0.02888971776240171 0.07024222277373458 5.521904101157387e-06 5.257911140018345 0.20886726784270648 NENTEGS(ph)PQEDGVELEGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NENTEGSPQEDGVELEGLK 19 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 NENT(0.005)EGS(0.995)PQEDGVELEGLK;NENT(0.001)EGS(0.999)PQEDGVELEGLK 201.96 2.3593999999999997e-59 3465900.0 32609.0 40028.0 33879.0 33867.0 40698.0 32348.0 37653.0 35047.0 26224.0 26108.0 True False 38129.05964289228 44001.715304163874 34686.80384682299 31969.54178829545 32723.51905303752 30651.61393460055 34086.23525588694 34127.053385365994 26607.476389066163 30841.173729185713 1.2363037794119318 1.4267198677501705 1.1246914320254313 1.0365864175280053 1.061033517737702 0.9938536776761587 1.105218483420764 1.106541978104769 0.8627258035866157 1.0 14.912570050802831 -5.448905665987749 4.121377904680289 1.0338646978964259 1.3292287578906357 0.702491386865937 0.07883412559211211 0.11509498214024026 3.674162816278574 0.020417611342805213 0.04405773381481293 3.557085743812375e-06 5.448905665987749 0.2953640599942098 NENTEGS(ph)PQEDGVELEGLK ddPTM_PC-9_Lapatinib_30min_R1 3 NENTEGSPQEDGVELEGLK 19 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 NENT(0.001)EGS(0.999)PQEDGVELEGLK;NENT(0.001)EGS(0.999)PQEDGVELEGLK;NENTEGS(1)PQEDGVELEGLK 225.83 3.5316999999999996e-35 9333300.0 37398.0 56335.0 65772.0 58291.0 63227.0 57489.0 70022.0 62540.0 58708.0 56834.0 True False 36864.69766204675 56204.559768712046 60364.48004726217 62577.914593075635 59508.11216906475 55030.32948340448 73647.39653972263 65445.836713494784 52095.686817352995 66657.6811734553 0.5530450056628606 0.8431820426284804 0.9055892582009103 0.9387952519715863 0.8927420084448169 0.8255662140452447 1.104859863757919 0.981819882740789 0.7815406401820463 1.0 16.024483510712827 -4.415767799033439 1.4725841455988518 0.9328834523788079 6.309405350068097e-12 0.6351987769431455 0.08551111357939847 1.951467322523226 1.9299753163319529 0.02451329913485456 3.4664290413522787 3.839124542151665e-05 4.415767799033439 -0.9328834523724985 NES(ph)PPQVPVYNNSHK ddPTM_PC-9_AZD4547_30min_R2 2 NESPPQVPVYNNSHK 15 0 A0A087WTW5;Q9UKL3 A0A087WTW5 CASP8AP2 CASP8-associated protein 2 1 NES(1)PPQVPVYNNSHK;NES(0.999)PPQVPVY(0.001)NNSHK 105.52 0.0017652000000000002 0.0 26768.0 32722.0 33963.0 29980.0 33961.0 37756.0 39301.0 34487.0 33187.0 34388.0 True False 35279.667191011846 43298.74658641407 33512.628428970034 23068.574186382702 29246.101359530974 35395.11135141912 42798.71286387471 29157.82658242107 34941.19706739668 33184.08658689257 1.063150166831683 1.3048045325290558 1.0099005841615432 0.6951697804300749 0.8813291058336057 1.066629068084697 1.2897360532074984 0.878668951940903 1.0529503946388012 1.0 15.018203943227327 -5.404975837783963 7.302354158251934 0.977934882909476 1.1818295234634733 0.2117195542862952 0.15481102128777718 0.4020472659165686 22.57531489256659 0.04355732075792434 0.09121532526064523 3.935719714430994e-06 5.404975837783963 0.2038946405539972 NES(ph)PPQVPVYNNSHK ddPTM_PC-9_Lapatinib_30min_R1 2 NESPPQVPVYNNSHK 15 0 A0A087WTW5;Q9UKL3 A0A087WTW5 CASP8AP2 CASP8-associated protein 2 1 NES(1)PPQVPVYNNSHK;NES(1)PPQVPVYNNSHK 84.10700000000001 0.0035193000000000004 3495000.0 30016.0 43572.0 37926.0 36531.0 54943.0 42926.0 35400.0 41064.0 43499.0 36156.0 True False 29587.966335739733 43471.1117110557 34807.87067859369 39217.61160384361 51711.3607620941 41090.15504539339 37232.83878646971 42971.983351502226 38599.68455522309 42405.51642515835 0.6977386158699339 1.025128694937085 0.8208335521635782 0.9248233463459622 1.2194489095153378 0.9689813616092509 0.8780187561724919 1.013358331040341 0.9102514910612588 1.0 15.371964333053613 -4.754641539732763 24.99682614695994 0.9721249285306565 0.6977381474107107 0.3960761629815681 0.10211585651300108 257.2135976576261 945734.2337583551 0.02624331275665615 0.25100978282142183 1.7593751771785617e-05 4.754641539732763 -0.27438678111994574 NESS(ph)PAPPDSDADKLK ddPTM_PC-9_AZD4547_30min_R2 2 NESSPAPPDSDADKLK 16 1 Q8ND04-2;Q8ND04;J3KTD7 Q8ND04-2 SMG8 Protein SMG8 1 NES(0.274)S(0.726)PAPPDSDADKLK;NES(0.06)S(0.94)PAPPDSDADKLK 87.66799999999999 0.001975 24142000.0 61049.0 81721.0 68906.0 50795.0 57889.0 83778.0 77256.0 79506.0 75521.0 67547.0 True False 80461.3121019158 108135.7151087447 67992.26141761939 39084.997524926934 49852.11158687574 78539.3484161243 84131.63433529685 67220.17456612537 79512.88588082268 65182.20008970672 1.2344062027851357 1.6589761462473405 1.043110869593928 0.5996268532074152 0.7648117356926736 1.2049201823202478 1.2907148611048884 1.0312658129614203 1.2198558160263602 1.0 15.99219042762074 -5.333135662696094 8.178773618171663 1.0117141322439784 1.4456004659653952 0.37797377293341905 0.21923821742595767 0.32637110743481945 34.26268424702419 0.06287742668097455 0.1316158987689028 4.6437019497020746e-06 5.333135662696094 0.4338863337214167 NESS(ph)PAPPDSDADKLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NESSPAPPDSDADKLK 16 1 Q8ND04-2;Q8ND04;J3KTD7 Q8ND04-2 SMG8 Protein SMG8 1 NES(0.227)S(0.773)PAPPDSDADKLK 62.739 0.017095 7572900.0 21561.0 32246.0 23251.0 28979.0 27304.0 17490.0 25988.0 15154.0 17749.0 18223.0 True False 25210.851450838745 35447.16977361016 23805.392019908544 27355.400581185622 21953.97720340399 16572.793610614677 23526.22850317343 14756.223556990222 18008.545547190944 21526.685646811366 1.1711441261545572 1.6466617460389572 1.1058549565169458 1.2707669461990603 1.01984938896787 0.7698720500928352 1.0928867030052185 0.685485160098298 0.8365684268659562 1.0 14.393838591809386 -6.183047308761175 1.1996459567420987 0.859274123685916 1.37733511713369 0.5741301094418261 0.17063638243016366 0.3123476558505229 0.920487468125665 0.06551796495121971 0.10371518224041724 6.560737946854994e-07 6.183047308761175 0.518060993447774 NESS(ph)PAPPDSDADKLK ddPTM_PC-9_Lapatinib_30min_R1 1 NESSPAPPDSDADKLK 16 1 Q8ND04-2;Q8ND04;J3KTD7 Q8ND04-2 SMG8 Protein SMG8 1 NES(0.207)S(0.793)PAPPDSDADKLK 141.64 1.1434000000000001e-05 21861000.0 42187.0 95439.0 59649.0 68623.0 97287.0 78360.0 79324.0 89671.0 61791.0 73779.0 True False 41585.4056438517 95218.01685925486 54744.88947179858 73669.76433961712 91564.76993360123 75008.72546608174 83431.00858468705 93837.44202007994 54831.44689192369 86531.60184566182 0.4805805596667866 1.100384308487507 0.6326577609119247 0.8513625400234109 1.0581656641109753 0.8668362062667887 0.9641680820088712 1.0844297345546525 0.6336580592801382 1.0 16.400939489175173 -4.744450902080581 24.94840233222548 0.9072689576957409 0.4805792616090895 0.39125270096483766 0.16072351713275135 1058.2264959464692 1553971.936984273 0.03833978213757854 1.0904229497732438 1.8011467464216842e-05 4.744450902080581 -0.4266896960866514 NEVNGTSEDIKS(ph)EGDTQSN ddPTM_PC-9_AZD4547_30min_R2 1 NEVNGTSEDIKSEGDTQSN 19 1 O95232 O95232 LUC7L3 Luc7-like protein 3 1 NEVNGTSEDIKS(0.515)EGDT(0.176)QS(0.309)N 101.23 0.0019592 4600000.0 18796.0 23426.0 14222.0 10650.0 12642.0 19013.0 20319.0 20025.0 19082.0 19197.0 True False 24772.737018912834 30997.99637960196 14033.406987510274 8194.807040859769 10886.87651680428 17824.114104368353 22127.35163688126 16930.59637872188 20090.63556332491 18524.91887311205 1.3372656144189201 1.6733134753207437 0.7575421562508989 0.4423666898079701 0.5876882156070335 0.9621696173924477 1.1944641587066789 0.9139363305550425 1.0845194897174648 1.0 14.17717960404465 -8.271430427563683 23.421047152758597 1.042259703352417 0.9741261015666303 0.004127620522069275 0.3399456743449943 3821.1221490473213 8957251.687659541 0.3523735683187074 0.09580089631574545 5.352658946020772e-09 8.271430427563683 -0.06813360178578676 NEVNGTSEDIKSEGDTQS(ph)N ddPTM_PC-9_AZD4547_30min_R2 1 NEVNGTSEDIKSEGDTQSN 19 1 O95232 O95232 LUC7L3 Luc7-like protein 3 1 NEVNGTSEDIKS(0.122)EGDT(0.048)QS(0.83)N 129.06 7.9391e-06 0.0 12200.0 16044.0 10842.0 9671.5 10405.0 16514.0 14525.0 14887.0 16081.0 9448.1 True False 16079.346224235807 21229.909242479895 10698.227995963043 7441.885098185474 8960.445353373561 15481.376969417703 15817.69686134655 12586.5562192276 16931.008829987823 9117.324894777821 1.7636035141673694 2.3285239351994425 1.1733954991656297 0.8162355936715606 0.9827932487637776 1.6980174720202252 1.7349054732497837 1.3805097837894171 1.8570149715390187 1.0 13.154394871424016 NEVNGTSEDIKSEGDTQS(ph)N ddPTM_PC-9_Lapatinib_30min_R1 2 NEVNGTSEDIKSEGDTQSN 19 1 O95232 O95232 LUC7L3 Luc7-like protein 3 1 NEVNGTSEDIKS(0.171)EGDT(0.049)QS(0.78)N;NEVNGTSEDIKS(0.002)EGDT(0.087)QS(0.911)N 161.14 2.4334e-05 6570300.0 26471.3 38628.3 24995.9 33323.8 38964.1 36736.5 36528.1 43129.0 31379.9 33162.3 True False 26093.814407758124 38538.8585446657 22940.833588964295 35774.54341693804 36672.30824436799 35165.36553196417 38419.34628463402 45132.930790155326 27845.56521700372 38894.35936901285 0.670889425384059 0.9908598359732755 0.5898241791646854 0.9197874446915209 0.9428695790162527 0.9041250737241974 0.9877870958132486 1.1603978448893737 0.715928110624398 1.0 15.247273323953529 -5.975606982065263 24.766556005837085 0.9567404942345032 0.7712658595492576 0.29123822190218096 0.14017168332006716 265.2214716804399 269280.6767678539 0.03750852614998564 0.05563136154435836 1.0577743167373094e-06 5.975606982065263 -0.1854746346852456 NFAFLEFR ddPTM_PC-9_Lapatinib_30min_R1 1 NFAFLEFR 8 0 P26368;P26368-2;K7ENG2 P26368 U2AF2 Splicing factor U2AF 65 kDa subunit 0 105.14 0.017725 1352700.0 7819.8 7029.7 6955.9 6835.3 6876.0 5988.6 6551.9 6699.4 7919.1 7213.0 False True 7708.288218024313 7013.42316155348 6384.012752550488 7337.990763892366 6471.567198736131 5732.481538108435 6891.125323307085 7010.67858136212 7027.167566180076 8459.757439281639 0.9111713040650564 0.8290335995908915 0.7546330729185289 0.867399664418212 0.7649825949720924 0.6776177188592313 0.8145771758548488 0.8287091718267318 0.8306582802895102 1.0 13.04640058321272 -8.996464661773516 1.2856020903195884 0.999901185514151 0.8004384928858466 0.4773139128738083 0.06057921474379332 1.8353154627758168 4.045592922113421 0.06097706817685713 0.01819276003109268 1.0081736403835441e-09 8.996464661773516 -0.1994626926283044 NFDEILR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NFDEILR 7 0 P30041 P30041 PRDX6 Peroxiredoxin-6 0 110.12 0.043826 5504300.0 38459.0 36907.0 37859.0 43857.0 47887.0 40191.0 43809.0 35733.0 36231.0 37406.0 False True 44969.34910012555 40570.883050134296 38761.70214105702 41399.83447631244 38503.8861097058 38083.31320778812 39659.09437030652 34795.04661224307 36760.80983268216 44187.41169426691 1.0176959313948704 0.9181547751844935 0.8772114196063254 0.9369146752192289 0.8713768160062084 0.8618588812417186 0.8975201952245617 0.7874425153704476 0.8319294664061909 1.0 15.431347806340046 -1.5228792614682514 0.6894527517819915 0.8686043196859584 17.627199646567977 0.3442474248705921 0.054711128538280744 284.21689848141455 1.5738552480415422 0.021331546008688217 7328.670166313311 0.029999964343023326 1.5228792614682514 16.75859532688202 NFDFEGSLS(ph)PVIAPK ddPTM_PC-9_AZD4547_30min_R2 2 NFDFEGSLSPVIAPK 15 0 Q9H1A4;H0Y564 Q9H1A4 ANAPC1 Anaphase-promoting complex subunit 1 1 NFDFEGS(0.038)LS(0.962)PVIAPK;NFDFEGS(0.124)LS(0.876)PVIAPK 158.14 0.00011348 167694000.0 366700.0 333710.0 467180.0 590520.0 534100.0 428480.0 435710.0 469280.0 381800.0 456170.0 True False 483302.9721661699 441575.23144527304 460984.88795001025 454384.7374430532 459949.434237081 401687.0778646063 474487.34591788636 396763.55898160266 401981.1685398518 440199.6271473414 1.0979177226890318 1.003124955618082 1.0472178064696809 1.0322242669482404 1.0448655697818867 0.9125111724144093 1.0778912944400754 0.9013264312666035 0.9131792572039201 1.0 18.747798397692385 -6.814980809702497 0.7953133593765267 0.9468912035608773 1.051504615590813 0.33084423185365996 0.055349514716213966 0.7527176499637065 1.0330799366702461 0.03750306256332568 0.03411920412031612 1.5311551177870056e-07 6.814980809702497 0.10461341202993568 NFDFEGSLS(ph)PVIAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NFDFEGSLSPVIAPK 15 0 Q9H1A4;H0Y564 Q9H1A4 ANAPC1 Anaphase-promoting complex subunit 1 1 NFDFEGS(0.041)LS(0.959)PVIAPK;NFDFEGS(0.014)LS(0.986)PVIAPK;NFDFEGS(0.326)LS(0.674)PVIAPK;NFDFEGS(0.28)LS(0.72)PVIAPK 197.51 8.734700000000001e-10 80132600.0 228868.0 238809.0 238222.0 295245.0 322610.0 293458.0 338083.0 310978.0 279499.0 258980.0 True False 267610.8320509518 262516.3792863015 243902.1159419665 278703.3798472049 259396.88637526275 278068.5458767157 306057.3307310441 302815.1570084266 283586.1441148413 305931.0239154485 0.8747423802461843 0.8580900881724708 0.7972454470958616 0.9110007095070926 0.8478933684311578 0.9089256209385508 1.0004128604349407 0.9898151326166807 0.9269610531333927 1.0 18.222846889863405 -7.031144710087545 3.381331969882363 0.9779663031964902 0.8577430981624669 0.7516208549751617 0.032840166142663545 0.12309735190804379 2.8951172715887923 0.012998084837305876 0.010362861296884516 9.307976752189509e-08 7.031144710087545 -0.1202232050340234 NFDFEGSLS(ph)PVIAPK ddPTM_PC-9_Lapatinib_30min_R1 2 NFDFEGSLSPVIAPK 15 0 Q9H1A4;H0Y564 Q9H1A4 ANAPC1 Anaphase-promoting complex subunit 1 1 NFDFEGS(0.026)LS(0.974)PVIAPK;NFDFEGS(0.014)LS(0.986)PVIAPK 184.22 4.9576e-07 97330000.0 147783.0 125594.0 135157.0 128195.0 143001.0 141836.0 142261.0 133541.0 153216.0 115156.0 True False 145675.58731991664 125303.19480947248 124044.91318110767 137622.8879459834 134589.96233078314 135770.00491586485 149626.57849158114 139745.8023753884 135959.20064399327 135060.56116427504 1.0785945657572862 0.9277556211029316 0.9184391958081014 1.0189716876608546 0.9965156458004086 1.0052527824960455 1.1078480438829907 1.03468992850855 1.006653603923837 1.0 17.04324693134103 -6.643752635002282 1.7474515718346806 1.039677707226903 0.9768225942313324 0.15281349824302382 0.050773756057678525 0.5630926339537948 3.536657992256627 0.02078932711857217 0.02073481063069799 2.2711580874019467e-07 6.643752635002282 -0.06285511299557056 NFDRENVR ddPTM_PC-9_AZD4547_30min_R2 2 NFDRENVR 8 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 0 ; 104.75 0.0049946999999999995 6630800.0 32490.0 27868.0 38309.0 67971.0 55510.0 38911.0 30217.0 39331.0 34622.0 42050.0 False True 42821.14416601818 36875.78601155756 37800.997629344056 52301.33609148166 47803.394672346614 36477.889018833244 32906.254461914534 33253.29768646745 36452.04823778615 40577.842299023876 1.0552839121031399 0.9087665563835223 0.9315674636118684 1.2889136811678081 1.1780664511453471 0.8989607862838666 0.8109414546841519 0.8194939849541328 0.8983239662958379 1.0 15.308404532291634 -6.892479199225909 6.975567801521797 0.8656271705925026 1.0670282842605936 0.39982385438165746 0.11378422211222271 0.24267938498610453 14.173342332220317 0.04434025397566353 0.039107769410557464 1.280916443267658e-07 6.892479199225909 0.201401113668091 NFDRENVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NFDRENVR 8 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 0 82.241 0.02171 2237500.0 11812.0 8878.2 13043.0 20745.0 18928.0 18267.0 14515.0 16591.0 16433.0 14603.0 False True 13811.538302365725 9759.569022020278 13353.994585852954 19582.724906197443 15219.194275784908 17309.046362784356 13140.034120500331 16155.503829617577 16673.30153681835 17250.408302715612 0.8006499359317466 0.565758725866442 0.7741262903180516 1.1352035593913838 0.8822512492871868 1.003399227371303 0.7617230786607982 0.9365287792680437 0.9665453271731307 1.0 14.074342889227601 -5.533192304573432 24.870971980986674 0.9442379556051862 0.6798888551484508 0.5399504728007998 0.1041140388401044 133.37698610495272 321635.2382855371 0.027344422164501905 0.04742619185299779 2.929595739913572e-06 5.533192304573432 -0.26434910045673543 NFDRENVR ddPTM_PC-9_Lapatinib_30min_R1 1 NFDRENVR 8 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 0 93.14299999999999 0.0096515 3074200.0 23268.0 13246.0 22537.0 15469.0 19171.0 17774.0 14134.0 12886.0 18390.0 12539.0 False True 22936.19405317139 13215.32970083181 20684.094855335792 16606.64186307126 18043.399471636174 17013.847453217673 14865.789361806867 13484.730602655802 16318.72454471487 14706.349442832727 1.5596116590544877 0.8986138777813701 1.4064737775843055 1.12921578041005 1.2269121947479487 1.1569048810756721 1.0108415701390696 0.9169325572654408 1.1096380245927007 1.0 13.844151550388505 -7.12852422863732 2.669868363998439 1.000088187891272 1.2272979877641097 0.3021273568050208 0.16712874151419316 0.3639997782537696 5.036440948834203 0.06690402459216081 0.04938546596537546 7.438335643918573e-08 7.12852422863732 0.22720979987283774 NFDT(ph)LDLPK ddPTM_PC-9_AZD4547_30min_R2 3 NFDTLDLPK 9 0 C9JJX6;E9PDC3;O00192-2;O00192 C9JJX6 ARVCF Armadillo repeat protein deleted in velo-cardio-facial syndrome 1 NFDT(1)LDLPK;NFDT(1)LDLPK;NFDT(1)LDLPK 114.76 0.00057823 9889300.0 71747.0 91871.0 79166.0 83643.0 80645.0 86330.0 94321.0 89961.0 90557.0 90039.0 True False 94561.05356969232 121566.50411467643 78116.20711385451 64360.39862146798 69448.83378402783 80931.77145269651 102715.38627601125 76059.59454812473 95343.65814422036 86886.76201573857 1.0883252106064631 1.3991372367249226 0.8990576389497014 0.7407388321112693 0.7993028186669903 0.9314626253195697 1.1821753267477675 0.8753876054714456 1.0973323891037614 1.0 16.40684876569066 -5.275938230237049 24.824831063875408 0.9323370914906309 1.2437312254221509 0.42104857931343753 0.14187406013252576 601.3263940202937 1029587.010575891 0.038657922153555985 0.08104253111895325 5.297387833526263e-06 5.275938230237049 0.31139413393151993 NFDT(ph)LDLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NFDTLDLPK 9 0 C9JJX6;E9PDC3;O00192-2;O00192 C9JJX6 ARVCF Armadillo repeat protein deleted in velo-cardio-facial syndrome 1 NFDT(1)LDLPK;NFDT(1)LDLPK;NFDT(1)LDLPK;NFDT(1)LDLPK 112.43 0.0045173999999999995 10114700.0 103750.0 102392.0 87003.0 89252.0 119438.0 66738.0 85641.0 77114.0 85145.0 70589.0 True False 121312.82584409458 112556.80107484605 89077.48148071494 84251.49979888817 96034.98129285713 63238.14179446555 77528.46449285332 75089.83920903661 86390.08454648542 83386.22691778351 1.4548304957328941 1.349824848003063 1.0682517338090238 1.0103766882504204 1.1516887721463276 0.7583763426161084 0.9297514392789857 0.9005064983102437 1.0360234266465087 1.0 16.347521489858046 -5.017480776762732 0.8944459679197867 0.9395938456753937 1.663322532838055 0.7665342217266713 0.0951791894191367 0.7539784568281238 0.6034374772131217 0.03502703656611547 0.49688682536445833 9.60548334330767e-06 5.017480776762732 0.7237286871626613 NFDT(ph)LDLPK ddPTM_PC-9_Lapatinib_30min_R1 2 NFDTLDLPK 9 0 C9JJX6;E9PDC3;O00192-2;O00192 C9JJX6 ARVCF Armadillo repeat protein deleted in velo-cardio-facial syndrome 1 NFDT(1)LDLPK;NFDT(1)LDLPK 108.98 0.0058658 8230700.0 55855.0 80389.0 57985.0 49919.0 62046.0 51985.0 47349.0 45971.0 56936.0 44086.0 True False 55058.49745744748 80202.86420958552 53217.69712857282 53590.209784902385 58396.57626712939 49761.72273295377 49800.499539563694 48106.98048538645 50523.26811734018 51706.2063590975 1.0648334375001032 1.5511264480047111 1.02923228904047 1.0364366979994732 1.12939200879615 0.9623936126228374 0.9631435575393261 0.9303908345409335 0.9771219293571479 1.0 15.658049838931007 -5.408114511083991 8.798441114946293 1.0018220284933832 1.3072929255812638 0.5076491354286521 0.12021574175914033 0.22752693663032375 16.028865129418893 0.029768316303881603 0.0621048393577912 3.907378557662487e-06 5.408114511083991 0.30547089708788056 NFEDVAFDEK ddPTM_PC-9_Lapatinib_30min_R1 2 NFEDVAFDEK 10 0 P07237;H7BZ94;H0Y3Z3 P07237 P4HB Protein disulfide-isomerase 0 ; 109.24 0.008538200000000001 0.0 40161.0 40177.0 42382.0 35731.0 44476.0 33414.0 43376.0 42986.0 39866.0 41475.0 False True 39588.29677537459 40083.97262496754 38897.515559251115 38358.7769351218 41860.00912318036 31984.96111183837 45621.79703960199 44983.28648810818 35375.87127240909 48643.898488036306 0.8138388987287092 0.8240287861554921 0.7996381204688547 0.7885629673484318 0.8605397680754472 0.6575328480241955 0.9378729595618742 0.9247467387748859 0.727241696738381 1.0 15.56997123546858 -14.52287874528031 0.25078760777292786 2.1110357444519856 0.8015963894469011 0.3198455015064525 0.07977617354519892 222.56109868552574 2.2011539649878284 126.79089861908221 0.11301514405190646 3.0000000000001852e-15 14.52287874528031 -1.3094393550050845 NFEHLNSDFDR ddPTM_PC-9_AZD4547_30min_R2 4 NFEHLNSDFDR 11 0 P48163 P48163 ME1 NADP-dependent malic enzyme 0 ;;; 152.96 0.00010327 24526800.0 148182.0 137449.0 207989.0 272904.0 236849.0 217661.0 184586.0 268524.0 188468.0 211623.0 False True 195300.79362292762 181876.70128830834 205230.92996240163 209990.19912476934 203966.6046613336 204050.62326150102 201013.79640953653 227029.7858676615 198430.0337149523 204214.14318302766 0.9563529272695309 0.8906175569108389 1.0049790223317818 1.0282843090674914 0.9987878482957363 0.9991992722982949 0.9843284763552209 1.1117241065139414 0.9716762542597682 1.0 17.63972326030695 -5.34656292816578 6.170593160852773 1.0155335985893192 0.9239654808310622 0.451576376491571 0.03914066199788872 0.17774386479955012 10.35870778687927 0.009974869784893826 0.021162482795368795 4.502327389827898e-06 5.34656292816578 -0.09156811775825702 NFEHLNSDFDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NFEHLNSDFDR 11 0 P48163 P48163 ME1 NADP-dependent malic enzyme 0 ;;; 158.06 5.4356000000000006e-05 24459800.0 107449.0 147552.0 145244.0 183184.0 196703.0 168312.0 180248.0 155209.0 139527.0 131980.0 False True 125637.99348551419 162199.98742280353 148707.1678009375 172920.79437054068 158160.4591943004 159485.42242365776 163173.60455748797 151134.92820752886 141567.31841584973 155906.9292468949 0.805852530688699 1.040364198091176 0.9538201317880116 1.1091283447492097 1.0144543283501968 1.0229527526072684 1.04660905930028 0.9693919887819157 0.9080245445131121 1.0 17.250325524140095 -4.756173929670302 24.99881509475928 1.0097060252338368 0.8058522118619973 0.569235645058803 0.05250368784829705 123.96887624808231 588503.6867857751 0.013213541390335516 0.10969931582412004 1.75317823461638e-05 4.756173929670302 -0.2038538133718395 NFEHLNSDFDR ddPTM_PC-9_Lapatinib_30min_R1 3 NFEHLNSDFDR 11 0 P48163 P48163 ME1 NADP-dependent malic enzyme 0 ;; 136.81 7.145e-05 18408100.0 107660.0 119655.0 127331.0 120334.0 139279.0 138807.0 110533.0 125556.0 142498.0 104299.0 False True 106124.74865757408 119377.9461990811 116862.3366918742 129183.76378245627 131086.8830530496 132870.54818492083 116255.85789787724 131389.79012471277 126448.37466953674 122326.94318031828 0.8675500744029787 0.9758924983771551 0.9553278587172012 1.0560532326229273 1.0716108785602414 1.0861920091394792 0.9503700074194461 1.0740870875113362 1.0336919355790914 1.0 16.900382674798955 -4.752860348298027 1.0232586587956836 1.039917067818491 0.7832368855440622 0.5860888837623576 0.042871656856915054 1.402495286152021 1.1363059463588834 0.014129313366274945 0.4024792177026914 1.766605798993809e-05 4.752860348298027 -0.2566801822744288 NFELVDS(ph)SPCKK ddPTM_PC-9_AZD4547_30min_R2 1 NFELVDSSPCKK 12 1 A0A087WUU7;Q96GX5-2;Q96GX5-3;Q96GX5 A0A087WUU7 MASTL Serine/threonine-protein kinase greatwall 1 NFELVDS(0.5)S(0.5)PCKK 102.73 0.0034027000000000003 9743900.0 60558.0 57864.0 62172.0 78850.0 78594.0 73049.0 68547.0 68577.0 73933.0 86168.0 True False 79814.18431535023 76567.40640780708 61347.55865753684 60672.350720356175 67682.5797311909 68481.23448219645 74647.55020686559 57980.00039268973 77840.94744278905 83151.28454749791 0.959867123516998 0.9208204879152532 0.7377824526871105 0.7296622180947637 0.8139691419021803 0.8235739815069051 0.8977317742364546 0.6972832796055031 0.936136439339365 1.0 16.343450930446124 -10.046334400565147 9.541889697940762 1.0000000000001668 0.8285677656579482 0.23655989413959566 0.0880924061097548 0.0 0.0 0.08641443533182398 0.02095857908536571 8.988052477821119e-11 10.046334400565147 -0.17143223434221855 NFELVDS(ph)SPCKK ddPTM_PC-9_Lapatinib_30min_R1 2 NFELVDSSPCKK 12 1 A0A087WUU7;Q96GX5-2;Q96GX5-3;Q96GX5 A0A087WUU7 MASTL Serine/threonine-protein kinase greatwall 1 NFELVDS(0.5)S(0.5)PCKK;NFELVDS(0.609)S(0.391)PCKK 164.15 5.6959e-13 32505000.0 298024.0 263092.0 252537.0 286339.0 278317.0 232038.0 240711.0 213683.0 254171.0 221996.0 True False 293774.1231090918 262482.82663832454 231774.38268101026 307397.3252589027 261946.94125227517 222114.27564699698 253173.83777203166 223611.49226814395 225543.58544071365 260367.71280892415 1.128304734637676 1.0081235641953525 0.8901809682182151 1.1806276667049425 1.0060653774091797 0.8530791827095697 0.9723703259544633 0.8588295755097928 0.8662502082438814 1.0 17.99019103101076 -6.607900382644368 6.152567673259399 0.9060713186459545 1.0437726492674324 0.38986523252684235 0.08407062544493081 0.2263325013865625 13.105839162149039 0.02780824257467333 0.027796882860122 2.4666050558987935e-07 6.607900382644368 0.13770133062147794 NFGDQPDIR ddPTM_PC-9_AZD4547_30min_R2 1 NFGDQPDIR 9 0 Q15393 Q15393 SF3B3 Splicing factor 3B subunit 3 0 93.598 0.028257 1653500.0 17928.0 17690.0 26594.0 31566.0 32133.0 31362.0 17459.0 32316.0 24125.0 28835.0 False True 23628.73107443441 23407.946553195547 26241.3461837891 24288.946389838457 27671.887605954144 29400.929182201675 19012.817177435398 27322.304747804083 25400.198247836342 27825.49542669094 0.8491755748495717 0.8412409624427399 0.9430684263259412 0.8729025671377576 0.9944796015890717 1.0566183541874887 0.6832876427133732 0.9819162005502269 0.9128390297580042 1.0 14.764119754206249 -5.255430455885633 23.910483766954954 0.9258764232658313 0.8452082492882854 0.11045006534434276 0.09622222974920971 632.8920279624563 2518343.7511396557 0.024495174671341356 0.06116437343749474 5.553535394512441e-06 5.255430455885633 -0.08066817397754589 NFGEDMDDER ddPTM_PC-9_AZD4547_30min_R2 1 NFGEDMDDER 10 0 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YAR2;H0YBN4;Q9H361 A0A087WTT1 PABPC1;PABPC3 Polyadenylate-binding protein;Polyadenylate-binding protein 1;Polyadenylate-binding protein 3 0 107.45 0.010088 0.0 24190.0 33995.0 31548.0 33459.0 24376.0 34058.0 36513.0 36454.0 28533.0 37009.0 False True 31881.916816743 44983.21894154226 31129.65290690299 25745.544486396895 20991.813160387694 31928.347876009968 39762.5862649464 30820.871929584388 30041.196128726006 35713.32617466289 0.8927176556117554 1.2595639712062432 0.8716537002086401 0.7208946139736007 0.5877865606167063 0.8940177602012829 1.1133823287833742 0.8630076005480135 0.841176091574438 1.0 15.124174885700311 -5.415967828391534 9.416933472608317 0.8505017019117616 1.07544725524379 0.2287884902916425 0.15707020102922672 0.524166980367405 42.72309061090662 0.04342716856488815 0.09053042686756053 3.837356707590493e-06 5.415967828391534 0.22494555333202837 NFGEDMDDER ddPTM_PC-9_Lapatinib_30min_R1 2 NFGEDMDDER 10 0 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YAR2;H0YBN4;Q9H361 A0A087WTT1 PABPC1;PABPC3 Polyadenylate-binding protein;Polyadenylate-binding protein 1;Polyadenylate-binding protein 3 0 ; 128.81 0.0012311 6134000.0 34858.0 49711.0 44966.0 45216.0 56073.0 49188.0 45464.0 43942.0 44430.0 42867.0 False True 34360.918527825685 49595.897233734744 41269.06905377956 48541.335476154294 52774.8963837596 47084.34390282835 47817.9034629395 45983.70573815779 39425.825531358474 50276.50383331293 0.6834389010370752 0.9864627301485666 0.8208420615443611 0.9654874896848153 1.049693044662172 0.9365079174743756 0.9510984220675988 0.9146162169631462 0.7841799354639124 1.0 15.617596709544328 -4.753926831802973 24.99463707932154 0.9332783964583156 0.6834384569177306 0.4965766297127512 0.07577512854879855 235.800943390998 784456.9180677447 0.01904297092339177 0.1952983442818925 1.7622729220951054e-05 4.753926831802973 -0.24983993954058492 NFGIGQDIQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NFGIGQDIQPK 11 0 P62424;Q5T8U3 P62424 RPL7A 60S ribosomal protein L7a 0 ; 161.17 0.0023501999999999998 1830000.0 33366.0 33011.0 28449.0 40172.0 37499.0 33557.0 36920.0 38009.0 33206.0 30079.0 False True 39014.204791460776 36288.11391790129 29127.332053433296 37921.293079381256 30151.34013882386 31797.211846277674 33422.670322347396 37011.304023864395 33691.5749304199 35532.08459476703 1.0979993219200703 1.0212773703472946 0.8197473462540109 1.067240875728583 0.8485665978422325 0.8948873168831921 0.9406335345511843 1.0416305276194016 0.948201472406204 1.0 15.116834710670341 -5.007687752058864 16.70980723971488 0.9438900380806597 1.0788275388178705 0.29899061386521986 0.07430541297393328 5.253204096979994 11446.815215743685 0.01822098987096702 0.05879204579022896 9.82454051464703e-06 5.007687752058864 0.13493750073721078 NFGIGQDIQPK ddPTM_PC-9_Lapatinib_30min_R1 2 NFGIGQDIQPK 11 0 P62424;Q5T8U3 P62424 RPL7A 60S ribosomal protein L7a 0 ; 179.42 0.0027344 7746600.0 116119.0 111284.0 109519.0 105010.0 118842.0 100021.0 139516.0 100741.0 95208.0 116065.0 False True 114463.12176638324 111026.32873526873 100514.77057556581 112732.7857030911 111851.94721236182 95743.33499033892 146739.4558229691 105421.79463310144 84484.67245531346 136126.68060310846 0.8408573635914359 0.8156103435665017 0.7383914022602749 0.8281461444856303 0.8216754181972441 0.703339966611605 1.0779624917969115 0.7744388841778173 0.6206327229974654 1.0 17.05459033482291 NFHENCYR ddPTM_PC-9_AZD4547_30min_R2 2 NFHENCYR 8 0 Q8WUP2-3;Q8WUP2 Q8WUP2-3 FBLIM1 Filamin-binding LIM protein 1 0 ; 102.51 0.0035719000000000002 5732100.0 23225.0 23071.8 31707.0 47429.0 36632.0 32784.0 26774.0 33001.0 27236.0 29126.0 False True 30610.06688998989 30529.308156360494 31286.544463014223 36494.976820745345 31546.27911434697 30734.01129740765 29156.83413188931 27901.45373753811 28675.63935660398 28106.30760526442 1.0890817577281657 1.0862084264189236 1.1131502900492747 1.2984621577937079 1.1223914417146075 1.0934916008551423 1.0373768956555547 0.9927114628287944 1.0202563694717737 1.0 14.77860631532145 -7.158179322913794 1.9904943151237806 1.006114872958874 1.1451261223962437 0.5401187937885653 0.05675707333002776 0.29003466593327376 2.255391426380106 0.02984630062417206 0.020574593469364917 6.94737396931304e-08 7.158179322913794 0.13901124943736964 NFHENCYR ddPTM_PC-9_Lapatinib_30min_R1 2 NFHENCYR 8 0 Q8WUP2-3;Q8WUP2 Q8WUP2-3 FBLIM1 Filamin-binding LIM protein 1 0 ; 85.161 0.011275 4751100.0 22701.7 19974.5 25280.0 24462.0 22029.4 21683.0 19381.0 18826.9 22448.2 19739.3 False True 22377.969595018094 19928.25027247962 23201.575983622006 26261.01708283982 20733.674003466804 20755.66863554174 20384.45334803868 19701.66650497753 19919.847325974373 23151.211704036068 0.9666003611861417 0.8607864904542093 1.0021754489669825 1.1343258149318207 0.8955761913685147 0.8965262337402107 0.8804918553997308 0.8509993669809878 0.8604235312012479 1.0 14.498800083776038 -6.4790694716686605 24.99985223771453 0.888272999767096 0.986533035870864 0.2788692889872153 0.07285149078561408 619.8699589583541 353730.19263144577 0.023658937838361507 0.026825002718665957 3.3184137049147205e-07 6.4790694716686605 0.0982600361037681 NFIGNSNHGSQS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 NFIGNSNHGSQSPR 14 0 Q03112;Q03112-3;E7EUL6;A0A0C3SFZ7;Q03112-5;Q03112-6;Q03112-1;Q03112-4 Q03112 MECOM MDS1 and EVI1 complex locus protein EVI1 1 NFIGNSNHGS(0.266)QS(0.734)PR;NFIGNSNHGS(0.009)QS(0.991)PR 117.53 7.2979e-05 12214100.0 9631.7 10001.8 41985.0 150225.0 63918.0 57381.0 19791.5 84191.0 27682.0 50874.0 True False 12694.380248194437 13234.686254140826 41428.25146748833 115592.94720311352 55044.08900499104 53792.956999040645 21552.90515878417 71181.2154667155 29145.214006076938 49092.916744840426 0.2585786522763203 0.26958443563106826 0.843874314553583 2.354574852496661 1.1212226254773519 1.095737645384335 0.4390227060821221 1.449928425248771 0.593674524525782 1.0 15.583227263269315 -5.3737914350729 4.3844523852492365 1.1638059254277355 0.2687232809596561 0.3327606566168503 0.4911709766336414 0.24996140655462426 7.800499285237959 0.1346375820788696 0.2974871775010959 4.228716447511847e-06 5.3737914350729 -0.8950826444680795 NFILDQTNVSAAAQR ddPTM_PC-9_Lapatinib_30min_R1 2 NFILDQTNVSAAAQR 15 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PRZ7;A0A1W2PQ74;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7;A0A1W2PQD4 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 ; 217.2 3.7575e-17 14235100.0 32206.0 33554.0 35373.0 31151.0 33136.0 27809.0 36758.0 24120.0 28091.0 27103.0 False True 31746.736534142932 33476.3077745516 32464.768483728687 33441.948456689686 31187.005627882547 26619.673895945212 38661.14938172468 25240.703254389104 24927.095768656112 31787.717437522573 0.998710794398491 1.0531208426760392 1.0212991400699603 1.0520399434913323 0.9811023924312684 0.8374201119745407 1.2162291758667967 0.7940394998161994 0.784173818634486 1.0 14.956181804965425 -7.807965531837789 24.999964927859832 0.8418296957987204 1.01633735461914 0.33941469027655136 0.10334353121504063 132.36715309760413 71123.27899365159 0.05391655463779427 0.02590081137037871 1.556089127081813e-08 7.807965531837789 0.17450765882041974 NFINNPLAQADWAAK ddPTM_PC-9_Lapatinib_30min_R1 2 NFINNPLAQADWAAK 15 0 P35579;Q5BKV1;B1AH99 P35579 MYH9 Myosin-9 0 ; 188.09 1.2882e-06 5709500.0 38579.4 44609.0 48700.0 44095.0 47273.0 41133.0 47776.0 40068.0 40420.0 40259.7 False True 38029.25068140452 44505.71060126879 44696.073987436364 47337.89339660789 44492.495082293906 39373.83747570623 50249.607510236645 41929.705555425484 35867.47395853046 47218.535502321785 0.805388186584791 0.9425474578532914 0.946578997250743 1.0025277762856546 0.9422675779537076 0.833864012444227 1.0641924188386955 0.8879925035659726 0.7596058110859203 1.0 15.527065676171016 -9.913099345011865 11.31155838027179 1.00000804873703 0.9169077932288618 0.08288401549539104 0.08724524840434017 0.0 0.0 0.08416130978541317 0.020412115872681633 1.2215202050370092e-10 9.913099345011865 -0.08310025550816813 NFITAEELR ddPTM_PC-9_AZD4547_30min_R2 2 NFITAEELR 9 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ; 114.86 0.0092785 8150100.0 56588.0 61130.0 75237.0 104759.0 87028.0 88209.0 64345.0 78604.0 68080.0 64121.0 False True 74581.80689648002 80889.07703769593 74239.30822101756 80608.43106041587 74945.66441262787 82693.27728565881 70071.58034721811 66457.5579402275 71678.56981192544 61876.14330691343 1.205340263799974 1.307274059349109 1.199805033949535 1.3027384505945683 1.2112206806569694 1.3364323124582893 1.1324490603697501 1.0740416966615014 1.1584201273888508 1.0 15.917095657050885 -7.433574641558562 5.342084024734998 1.0897257249554169 1.259067092378698 0.6872001832140899 0.05661397527268893 0.1250140285242752 5.708569506044057 0.022511012593180526 0.014809200735564574 3.684897046222351e-08 7.433574641558562 0.1693413674232811 NFITAEELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NFITAEELR 9 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ;; 116.3 0.0088764 11792600.0 65383.0 102761.0 94028.0 98241.0 89441.0 94060.0 105028.0 71825.0 68466.0 73883.0 False True 76451.05052688609 112962.43295621015 96269.98412317572 92736.87527161952 71915.67810759075 89127.3280168334 95078.98750312858 69939.66985487795 69467.1857250536 87277.40304249391 0.8759546900090891 1.2942918672913608 1.103034471320182 1.062553101247381 0.8239896651436364 1.0211959213937518 1.0893883661597517 0.8013491169166147 0.7959355263037694 1.0 16.41332055415488 -6.079187727459425 5.868286443778858 0.9256728807401937 1.1073211615862 0.2661186879859131 0.13140781203441051 0.29779665644322983 17.1761568952697 0.03944924511463432 0.051698342289087984 8.333208967576409e-07 6.079187727459425 0.18164828084600626 NFITAEELR ddPTM_PC-9_Lapatinib_30min_R1 4 NFITAEELR 9 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ;;; 137.05 0.0044563 40963500.0 169004.0 188765.0 192190.0 198589.0 196528.0 191400.0 221053.0 212850.0 198988.0 198693.0 False True 166593.97196846196 188327.92624018688 176388.8800748544 213193.89753348395 184968.60942891418 183214.26817519203 232498.04271936414 222739.78804712783 176575.87600346532 233036.82030821985 0.71488261703932 0.8081466524950865 0.7569142071264034 0.9148506972053121 0.7937312617991888 0.7862030898502161 0.9976880151894318 0.9558137111231053 0.7577166379541311 1.0 17.830198396180222 -1.5228787454953872 0.12377271376711657 1.0220816516214228 0.10728515429628808 0.3962986323055965 0.07928263714919004 95.76703054633721 0.8131474746001103 0.5041644114002444 15.164278025752655 0.0299999999851449 1.5228787454953872 -0.9147964973251348 NFLFVGVMT(ph)AQK ddPTM_PC-9_AZD4547_30min_R2 1 NFLFVGVMTAQK 12 0 Q86X52 Q86X52 CHSY1 Chondroitin sulfate synthase 1 1 NFLFVGVMT(1)AQK 105.52 0.0019347000000000001 0.0 7792.9 7138.6 9077.0 11472.0 10466.0 8888.6 12363.0 10140.0 7803.4 10963.0 True False 10270.880097610434 9446.012847068494 8956.633049193562 8827.307640633166 9012.976556310214 8332.794436863645 13463.283049695516 8573.095994019473 8215.871793043154 10579.188706877492 0.9708570649593737 0.8928863175422588 0.8466275909579803 0.8344030799729062 0.8519534726184542 0.787659117134996 1.2726196141054829 0.8103736715128387 0.7766069800515086 1.0 13.368941374350833 NFLFVGVMT(ph)AQK ddPTM_PC-9_Lapatinib_30min_R1 1 NFLFVGVMTAQK 12 0 Q86X52 Q86X52 CHSY1 Chondroitin sulfate synthase 1 1 NFLFVGVMT(1)AQK 105.1 0.0044773 2867500.0 14014.0 10801.0 11136.0 11479.0 12980.0 10978.0 7574.2 14384.0 9402.9 8139.3 True False 13814.157790147156 10775.990948111466 10220.441066203111 12323.203952821454 12216.541919661857 10508.496530967914 7966.355015154775 15052.333151373665 8343.846385073382 9546.167160064475 1.4470894505113459 1.1288290648410022 1.0706329456453896 1.2909059464592723 1.2797326628396632 1.100807932101719 0.834508225299186 1.5767933767537339 0.8740519881088096 1.0 13.220705883872714 -6.776956663920549 23.47355157769326 1.0981115316260464 1.230107660068219 0.1285450933313349 0.2115156146982143 316.85729166563254 479315.8480534033 0.07254801884538246 0.064255175685626 1.6712573724250996e-07 6.776956663920549 0.13199612844217268 NFLNALTS(ph)PIEYQR ddPTM_PC-9_AZD4547_30min_R2 2 NFLNALTSPIEYQR 14 0 E7EPJ7;O75962-4;O75962;O75962-5;O75962-2;E7EWP2 E7EPJ7 TRIO Triple functional domain protein 1 NFLNALT(0.07)S(0.93)PIEYQR;NFLNALT(0.215)S(0.785)PIEYQR 128.73 2.478e-05 12757500.0 75862.0 78963.0 96743.0 141523.0 117875.0 113701.0 85414.0 133715.0 98896.0 103598.0 True False 99984.5379723753 104486.24554437427 95460.12460924673 108897.05885855369 101510.09092060616 106591.25849580756 93015.6805311567 113052.4192150213 104123.44065981454 99971.0655527769 1.0001347631889679 1.0451648681209036 0.9548775346287698 1.0892857674010143 1.0153947080519692 1.0662210901366829 0.9304260189369663 1.130851397751067 1.0415357692155989 1.0 16.609222978198588 -5.762000167926717 24.99999981941574 1.0401682217853458 1.0045696493347804 0.09532901423849105 0.054519823778660347 40.43869175803321 1802937.7474638508 0.014625262162572619 0.0232687949032001 1.729815690354826e-06 5.762000167926717 -0.03559857245056541 NFLNALTS(ph)PIEYQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NFLNALTSPIEYQR 14 0 E7EPJ7;O75962-4;O75962;O75962-5;O75962-2;E7EWP2 E7EPJ7 TRIO Triple functional domain protein 1 NFLNALT(0.084)S(0.916)PIEYQR;NFLNALT(0.235)S(0.765)PIEYQR 130.66 1.8785e-05 6258400.0 32436.0 39733.0 39077.0 40082.0 49676.0 54372.0 52322.0 53882.0 47053.0 41946.0 True False 37926.774159798064 43677.429653750936 40008.74388034778 37836.335487597295 39942.34440214975 51520.6366035644 47365.68138152382 52467.654592698054 47741.06110946961 49550.4777556467 0.7654169218474586 0.8814734313792467 0.8074340691051851 0.7635917391994372 0.8060940320115879 1.0397606428263586 0.9559076627899131 1.0588728296715346 0.96348336629366 1.0 15.596611347200959 -6.7552789252095335 24.99757279805872 1.004303382214774 0.8069182875697279 0.8500811035755285 0.04173842308397366 52.99038074990201 215021.4177439336 0.013594251291189446 0.013268768034153302 1.7567949517035512e-07 6.7552789252095335 -0.19738509464504606 NFLNALTS(ph)PIEYQR ddPTM_PC-9_Lapatinib_30min_R1 1 NFLNALTSPIEYQR 14 0 E7EPJ7;O75962-4;O75962;O75962-5;O75962-2;E7EWP2 E7EPJ7 TRIO Triple functional domain protein 1 NFLNALT(0.012)S(0.988)PIEYQR 166.79 0.00019338 3498400.0 41247.0 38959.0 44763.0 34080.0 45225.0 50522.0 49984.0 46670.0 52911.0 50297.0 True False 40658.81021622657 38868.79282913382 41082.75893017687 36586.356887547285 42564.954415771 48361.291832534225 52571.92694640967 48838.45857721139 46951.6060024692 58990.76943346025 0.6892402083700305 0.6588961832914657 0.696426904153487 0.6202047750676579 0.721552792488712 0.8198111721035315 0.8911890360357 0.8279000095480981 0.7959144532845795 1.0 15.848201606322302 -6.7440149795728015 2.582375756662094 0.8638665674527757 0.6676753521034314 0.7615140134845129 0.054185357018936335 0.13728127029518 1.876454041685878 0.01948247536265221 0.018239344019359453 1.80295555271107e-07 6.7440149795728015 -0.19619121534934425 NFQAATESVPNSGNIHNGSLEQTEEPETSSHSPS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 NFQAATESVPNSGNIHNGSLEQTEEPETSSHSPSR 35 0 E7EUR8;A0A1B0GVL4;P78312-4;P78312-6;P78312-2;P78312-5;P78312 E7EUR8 FAM193A Protein FAM193A 1 NFQAATESVPNS(0.085)GNIHNGS(0.006)LEQT(0.007)EEPET(0.138)S(0.11)S(0.105)HS(0.17)PS(0.377)R 60.333999999999996 0.00028213 7118400.0 3736.5 2913.7 9483.6 19191.0 14726.0 11935.0 8419.7 16760.0 8647.7 12541.0 True False 4924.629275971895 3855.4965444910026 9357.841267525842 14766.811447994354 12681.549089262771 11188.702563279661 9169.036988879823 14170.12710648583 9104.799767370543 12101.94340718331 0.40692879732430415 0.3185849094454126 0.7732511178304916 1.220201661100916 1.04789360374429 0.924537670258681 0.757649964173307 1.1708968245608318 0.7523419554223199 1.0 13.562951122815617 -5.405049764150749 3.80319263167918 0.981384901955043 0.36526611475633786 0.7364494256870584 0.14595303099967055 0.11122120902703767 2.808264857839455 0.03899149742439322 0.08765039808383712 3.935049826349523e-06 5.405049764150749 -0.6161187871987052 down NFQTAHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NFQTAHR 7 0 O75475-3;O75475-2;O75475;V9GYT7 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 0 74.255 0.026818 0.0 3342.0 3616.7 2414.1 3745.4 5219.2 4656.3 3531.1 3309.9 4595.3 2127.8 False True 3907.7345924912147 3975.742074062393 2471.6612995252335 3535.557380750635 4196.5352263406885 4412.1154310523225 3196.6086450498606 3223.0186321289384 4662.497569046514 2513.553296344469 1.554665500100731 1.5817218118447802 0.9833335553774968 1.4065973400653549 1.6695628584616955 1.755329969517251 1.271748902121462 1.2822559349810743 1.8549427918744812 1.0 11.29551256432862 -10.753196385988845 4.866425506465845 0.9999153005586062 1.4715007754534133 0.25769474722334373 0.24578741619666303 0.00023212620630029803 3.671350279634266e-05 0.2445781385978379 0.05930831252237672 1.765239406951571e-11 10.753196385988845 0.47158547489480707 NFS(ph)CGSVEFDEADLESLR ddPTM_PC-9_AZD4547_30min_R2 1 NFSCGSVEFDEADLESLR 18 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 NFS(0.999)CGS(0.001)VEFDEADLESLR 144.75 0.00017853 5168400.0 8639.5 7074.9 10969.0 17469.0 15076.0 11017.0 10930.0 13756.0 12182.0 11602.0 True False 11386.681287236508 9361.72306778989 10823.543892982716 13441.79194335956 12982.95763070253 10328.105248399843 11902.748825784352 11630.326281433123 12825.915649954097 11195.817511373962 1.0170477748202529 0.8361803913183835 0.9667488668859555 1.2006083459027344 1.1596256921402115 0.9224967482640192 1.0631424470515183 1.03880991893783 1.1455988485810973 1.0 13.45067225624767 -5.537789889330276 24.579248318205146 1.074703032979417 0.9203266991966498 0.3470028479456755 0.08642629759329995 192.6249880459277 317518.0647491713 0.02377609709414102 0.04120234071752694 2.8987456549846433e-06 5.537789889330276 -0.15437633378276716 NFS(ph)CGSVEFDEADLESLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NFSCGSVEFDEADLESLR 18 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 NFS(0.786)CGS(0.212)VEFDEADLES(0.001)LR 57.17100000000001 0.035016000000000005 1822000.0 1446.6 1894.7 1645.2 1230.9 4652.5 1232.2 3552.2 3061.5 4020.2 3307.0 True False 1691.480808347633 2082.793294363927 1684.427807455746 1161.9366636316438 3740.876023250702 1167.5812628358722 3215.7099002990876 2981.138868927381 4078.987819528824 3906.532921802406 0.43298772650998507 0.5331564679104157 0.4311822890458531 0.2974342433278526 0.9575949052861757 0.2988791560720217 0.8231621145062347 0.7631162794737016 1.0441452564661482 1.0 11.931673057029913 -7.674911900503881 0.8226922146622841 1.0426567790273171 0.4709136641057839 0.5501657128692716 0.1862068911906087 0.4683029856355694 0.5878900496516012 0.1599683562277205 0.07401970930807981 2.113917818497614e-08 7.674911900503881 -0.5717431149215333 NFS(ph)CGSVEFDEADLESLR ddPTM_PC-9_Lapatinib_30min_R1 1 NFSCGSVEFDEADLESLR 18 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 NFS(0.544)CGS(0.456)VEFDEADLESLR 121.77 6.47e-05 4131700.0 2789.4 9243.2 6359.5 7357.6 12894.0 13327.0 17895.0 12179.0 14331.0 9970.2 True False 2749.6226444866893 9221.79793830052 5836.646458379909 7898.702448234096 12135.600270579358 12757.035276754354 18821.515539092536 12744.880801625408 12716.891867879767 11693.535785543576 0.2351403967896501 0.788623570101115 0.4991344419192361 0.6754759717757107 1.0378041760116983 1.090947640706377 1.6095658220297322 1.0899082224028067 1.087514683420334 1.0 13.513423604456264 -6.295065770361151 1.8074326676659271 1.2104094840008897 0.5265636557652467 0.6940501806204566 0.19977060567785737 0.19998430834415573 1.2883495007155463 0.07074275524463947 0.09118859974075395 5.069139344758448e-07 6.295065770361151 -0.683845828235643 NFS(ph)DNQLQEGK ddPTM_PC-9_AZD4547_30min_R2 2 NFSDNQLQEGK 11 0 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 1 NFS(1)DNQLQEGK;NFS(1)DNQLQEGK 118.73 0.0010348 36410000.0 90400.0 93598.0 130600.0 151906.0 147761.0 136307.0 118013.0 129842.0 116165.0 118390.0 True False 119145.31956319005 123851.72309135091 128868.15866747603 116886.41862430469 127246.93569051723 127783.70174218353 128515.92837852577 109777.9023723348 122305.24474445236 114245.2021351113 1.0428912316360004 1.0840868655900187 1.1279962419347027 1.0231188394771253 1.1138055105371472 1.118503878973062 1.1249131340022251 0.9608972658869884 1.0705503816239819 1.0 16.80177405327617 -7.753769525430882 24.999984305169836 1.011792863617564 1.0912868636563033 0.44384169864763123 0.041169054750190746 154.023112716546 502044.68095890305 0.019408046677060312 0.010931687500191698 1.7629113528906766e-08 7.753769525430882 0.07949400003873941 NFS(ph)DNQLQEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NFSDNQLQEGK 11 0 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 1 NFS(1)DNQLQEGK;NFS(1)DNQLQEGK;NFS(1)DNQLQEGK;NFS(1)DNQLQEGK 145.49 0.00013252 23302900.0 65578.0 78364.0 71310.0 92759.0 115369.0 106958.0 111601.0 104895.0 96633.0 89605.0 True False 76679.06017546053 86143.46003036608 73010.30084468097 87562.01395873571 92763.2726332961 101348.93419120213 101029.34535872936 102141.6173954395 98046.07481332505 105849.67718721034 0.724414681396171 0.8138282734486664 0.6897545914623034 0.8272298630053423 0.8763680258488739 0.9574798609158911 0.9544605901824761 0.9649686244653104 0.9262765595393975 1.0 16.69165734396067 -6.323948305522213 1.6588175110474033 0.9594583405645755 0.7496331868505623 0.8679124218538674 0.03678817308290998 0.12129383599044737 0.6626172762091908 0.012789314226658013 0.01635007680907159 4.742984380864141e-07 6.323948305522213 -0.2098251537140131 NFS(ph)DNQLQEGK ddPTM_PC-9_Lapatinib_30min_R1 2 NFSDNQLQEGK 11 0 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 1 NFS(1)DNQLQEGK;NFS(1)DNQLQEGK 138.73 0.00012166 19117000.0 61078.0 56744.0 58906.0 44494.0 56563.0 71211.0 66681.0 64143.0 60632.0 57034.0 True False 60207.016519666555 56612.61275434094 54062.97606373567 47766.237187632876 53236.07554713665 68165.47153094872 70133.41590736124 67123.31794553406 53802.985676734745 66892.25090697205 0.9000596586800055 0.8463254261405084 0.8082098498811434 0.7140772890728706 0.7958481711308051 1.0190339031309823 1.0484535197491966 1.003454316986333 0.8043231457640628 1.0 16.029551471946775 -6.756104415320713 24.98678622367599 0.9798564130452326 0.8090096279409903 0.5353521994505552 0.07542121636416559 106.3614481321839 498153.40211088536 0.026697150352924852 0.025950018333394477 1.753458875526632e-07 6.756104415320713 -0.17084678510424234 NFS(ph)INSVASTYSEFAR ddPTM_PC-9_AZD4547_30min_R2 1 NFSINSVASTYSEFAR 16 0 O43663-2;O43663-4 O43663-2 PRC1 Protein regulator of cytokinesis 1 1 NFS(0.999)INS(0.001)VASTYSEFAR 74.726 0.012925999999999998 2542700.0 4836.3 7552.1 7720.0 8279.6 8203.2 7532.3 7550.4 10844.0 6630.0 6648.3 True False 6374.142798710792 9993.168635635282 7617.627755841611 6370.866138544843 7064.327277539068 7061.3040902715875 8222.370972937066 9168.308970330096 6980.448264586735 6415.545040585028 0.9935465745135723 1.5576492055496525 1.1873703181338693 0.9930358368996641 1.10112659685963 1.1006553684217721 1.281632491225917 1.4290771730742997 1.0880522575132905 1.0 12.647356121130038 -12.084376524979161 1.2394022167623988 5.844678606668318e-05 1.201387342967256 0.09661807895251284 0.17465611116555133 150870.3613887862 9976.881649657247 417647.7799467361 0.05109574868374464 8.234239127318824e-13 12.084376524979161 1.2013288961811892 NFS(ph)INSVASTYSEFAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NFSINSVASTYSEFAR 16 0 O43663-2;O43663-4 O43663-2 PRC1 Protein regulator of cytokinesis 1 1 NFS(1)INSVASTYSEFAR 109.42 0.0039325 0.0 4340.2 3888.5 3798.3 5574.6 6073.7 3667.3 4067.2 5593.3 5560.7 4046.6 True False 5074.91013714254 4274.52458179877 3888.865877132964 5262.273235097048 4883.602085420263 3474.980332087321 3681.925372021974 5446.481801591219 5642.0147176891505 4780.216547132023 1.0616485858129845 0.8942114943230652 0.8135334118840619 1.1008441109753162 1.021627793901987 0.7269504002223912 0.7702423803856776 1.1393797222134077 1.180284336924899 1.0 12.222860259436553 -7.78508858666565 24.987397027318394 1.1198741982410314 0.9124746710393106 0.3389709364848331 0.12362128769855714 277.7208113842593 293431.282876803 0.07143026295881716 0.03434441825200161 1.6402551625557513e-08 7.78508858666565 -0.20739952720172083 NFS(ph)IQVR ddPTM_PC-9_AZD4547_30min_R2 1 NFSIQVR 7 0 I3L4X8;H3BM21;P05106-2;P05106-3;P05106 I3L4X8 ITGB3 Integrin beta;Integrin beta-3 1 NFS(1)IQVR 58.981 0.045868 991120.0 3928.4 3849.6 4373.8 5712.9 4304.0 4353.5 4481.8 3527.2 4241.8 5449.1 True False 5177.5494842039325 5093.907916968997 4315.800554209848 4395.879168425145 3706.463892447842 4081.2749567857586 4880.671517602954 2982.15228699265 4466.012888193668 5258.328667576958 0.9846378595786314 0.9687313667512293 0.8207551918200223 0.8359841018554608 0.7048748997570332 0.7761544047162829 0.9281792421415855 0.5671293058154975 0.8493217466095764 1.0 12.360388603922031 -5.290509607926359 2.182133413533718 0.7898729720778894 0.9932615045534567 0.24961997346906362 0.11228028571230146 0.41295458361307164 3.6527260835261637 0.030032147130627056 0.10507596824515228 5.122599373777472e-06 5.290509607926359 0.20338853247556732 NFS(ph)YVSPELQP ddPTM_PC-9_AZD4547_30min_R2 1 NFSYVSPELQP 11 0 P24723-2;P24723 P24723-2 PRKCH Protein kinase C eta type 1 NFS(0.998)YVS(0.002)PELQP 101.89 0.008818600000000001 0.0 9799.6 9446.7 13207.0 17415.0 10484.0 13693.0 13663.0 12358.0 10690.0 10623.0 True False 12915.668955657482 12500.16103471296 13031.866550699504 13400.240809067884 9028.477567012822 12836.774545369795 14878.980531261806 10448.355058589012 11255.051575932464 10251.09200338955 1.2599310347996957 1.2193979949238334 1.271266177924311 1.3072013015430022 0.8807332491043425 1.2522348390908287 1.451453223358256 1.0192431260137198 1.097936841480981 1.0 13.323489981373838 -14.327308800610536 0.09737013839381749 0.33012461933223536 1.350945262807492 0.18621517569479196 0.14705297736019898 344.59568155952235 2.3817922547749193 46.60158686076945 2.8704072475211873 4.706425618578533e-15 14.327308800610536 1.0208206434752567 NFS(ph)YVSPELQP ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NFSYVSPELQP 11 0 P24723-2;P24723 P24723-2 PRKCH Protein kinase C eta type 1 NFS(0.998)YVS(0.002)PELQP 113.24 0.0027761999999999995 0.0 7826.1 8332.2 7059.3 9447.1 8993.4 8266.3 8161.5 7362.9 8363.1 6524.8 True False 9150.9041574792 9159.365750408566 7227.620484544339 8917.809614911444 7231.207829662087 7832.80067601053 7388.383635856939 7169.63167663741 8485.39451606922 7707.69458971162 1.1872427028561827 1.188340513989055 0.9377149548960991 1.1570009048899148 0.9381803787755735 1.0162313237561207 0.9585724434020901 0.9301914590917463 1.1008991621691508 1.0 12.912083691968032 -5.248018687638924 24.307788182255383 1.0041624439520245 1.187791667350189 0.5211439571488221 0.07014287985117741 404.0351174374655 731790.5971168134 0.01719330238613257 0.04490650216144359 5.649126661657446e-06 5.248018687638924 0.18362922339816445 NFS(ph)YVSPELQP ddPTM_PC-9_Lapatinib_30min_R1 1 NFSYVSPELQP 11 0 P24723-2;P24723 P24723-2 PRKCH Protein kinase C eta type 1 NFS(0.972)YVS(0.028)PELQP 112.5 0.0016801 1166300.0 16865.0 16609.0 12966.0 8447.7 12959.0 15446.0 10569.0 13330.0 13223.0 7967.4 True False 16624.502007337785 16570.542880953926 11899.985530207397 9068.972038701091 12196.77709837427 14785.410586384613 11116.211105485827 13949.360463557496 11733.686495637028 9344.554474106832 1.7790577446365397 1.7732833520174611 1.2734674042707443 0.9705087667722028 1.3052283158250901 1.5822488517086661 1.1895924130238786 1.4927796185693272 1.2556710465063188 1.0 13.189910166040868 -5.26087744200157 19.03429453094459 1.2767442867132104 1.776171966753578 0.5715362746886196 0.1786757343676794 1.2769817806394677 43127.791655233086 0.04704548826115583 0.1099655327776345 5.484317106347016e-06 5.26087744200157 0.49942768004036764 NFSCGS(ph)VEFDEADLESLR ddPTM_PC-9_AZD4547_30min_R2 3 NFSCGSVEFDEADLESLR 18 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 NFS(0.241)CGS(0.759)VEFDEADLESLR;NFS(0.304)CGS(0.696)VEFDEADLESLR;NFS(0.004)CGS(0.996)VEFDEADLESLR 164.94 1.497e-07 9574300.0 31887.0 25242.300000000003 41049.0 49111.0 45525.8 41002.0 32085.9 50931.0 32859.5 39795.9 True False 42026.40270919732 33401.3798349196 40504.663439059885 37789.21770738632 39205.328502509794 38438.13845828178 34941.4829413755 43060.78422794927 34596.38608600117 38402.65765392923 1.0943618300567621 0.869767403493807 1.0547359457273286 0.9840261069410611 1.0209014400985978 1.0009239153360763 0.9098714796318376 1.121296984599279 0.9008852042942238 1.0 15.228918535586214 -4.453525422889685 21.77366435744851 0.9895032137761421 4.488133457383118 0.17112294904580172 0.07170243967883434 518.9915635226176 172254.6440294628 0.01581687266934879 5048.5220958550735 3.519448196467931e-05 4.453525422889685 3.4986302436069763 NFSCGS(ph)VEFDEADLESLR ddPTM_PC-9_Lapatinib_30min_R1 2 NFSCGSVEFDEADLESLR 18 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 NFS(0.313)CGS(0.687)VEFDEADLESLR;NFS(0.002)CGS(0.998)VEFDEADLESLR 153.36 4.5017e-12 3081700.0 15759.3 14065.599999999999 17753.2 18027.0 22990.0 20334.1 17610.1 15526.5 24695.3 17134.3 True False 15534.569492098324 14033.031967387893 16293.600425333783 19352.76571630911 21637.773400079044 19464.457944102254 18521.864811118943 16247.917872274975 21913.855260962322 20095.940924980358 0.7730202606630875 0.6983018122801139 0.8107906211587208 0.9630186408566 1.0767235772066839 0.9685765905047454 0.9216719376446438 0.8085173982611544 1.0904617675165533 1.0 14.294616507880324 -5.651180641646303 3.3962316275319098 0.9699450091983892 0.7384092035648105 0.631962947140265 0.07638869351042132 0.15726211702970816 3.527332627555781 0.022197821738045666 0.041166056697557234 2.2326433778177202e-06 5.651180641646303 -0.23153580563357867 NFSDNQLQEGK ddPTM_PC-9_Lapatinib_30min_R1 4 NFSDNQLQEGK 11 0 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 0 ;;; 187.31 0.0005739 68551000.0 219376.0 215395.0 191223.0 198207.0 209487.0 154788.0 197961.0 179887.0 179727.0 169713.0 False True 216247.65801136816 214896.2661113293 175501.38308212603 212783.80397916917 197165.3865272883 148168.0780684515 208210.45194938767 188245.2067297801 159484.2526507869 199047.66592164186 1.086411423163823 1.079622135312687 0.8817053054579139 1.0690092897795382 0.9905435746476196 0.7443849059088193 1.0460331247056818 0.9457292847829006 0.8012364873123923 1.0 17.602754428593954 -4.296335906270623 0.5584440601391537 0.9176611261730149 1.3389653295673432 0.24109653138640708 0.09930230293700801 9.563910850917527 1.5270720677703504 0.05243502315615573 2.9367313893864826 5.0543358177699414e-05 4.296335906270623 0.4213042033943283 NFT(ph)PPSPFANK ddPTM_PC-9_AZD4547_30min_R2 1 NFTPPSPFANK 11 0 K7EJT1;Q9NPG3-2;Q9NPG3 K7EJT1 UBN1 Ubinuclein-1 1 NFT(0.631)PPS(0.369)PFANK 115.57 0.0032909 5065200.0 30748.0 26095.0 31823.0 50819.0 43857.0 46562.0 36503.0 47682.0 36849.0 44817.0 True False 40525.2244018691 34529.698434462276 31401.006227221176 39103.46469572325 37768.21257692499 43650.4707793404 39751.69628431894 40313.84252335663 38796.76291127552 43247.970471233115 0.9370433793841243 0.7984119961751754 0.7260688972239268 0.9041687799369306 0.8732944497834171 1.009306802231911 0.9191574968994265 0.9321557077498434 0.8970770764163749 1.0 15.40034481149446 -6.217749457768913 2.1967785365613 0.9423450769687005 0.8214397613308281 0.40150114736495235 0.06286468513294971 0.31237608072287215 2.959536267400509 0.020913747198046024 0.02774579675754366 6.056901935111014e-07 6.217749457768913 -0.12090531563787243 NFT(ph)PPSPFANK ddPTM_PC-9_Lapatinib_30min_R1 1 NFTPPSPFANK 11 0 K7EJT1;Q9NPG3-2;Q9NPG3 K7EJT1 UBN1 Ubinuclein-1 1 NFT(0.99)PPS(0.01)PFANK 90.697 0.021018000000000002 3205700.0 40410.0 32625.0 34018.0 30633.0 33606.0 25943.0 24112.0 29957.0 32691.0 19905.0 True False 39833.7459897136 32549.458816974035 31221.171353277416 32885.85300869235 31629.361151938094 24833.478366086772 25360.401379077895 31348.91158340521 29008.995328508652 23345.552728254694 1.7062669902650687 1.3942466557058648 1.3373498463153115 1.408656003628957 1.354834538299779 1.0637348644151514 1.086305459299949 1.342821562132654 1.2425919260159386 1.0 14.510860125716706 -1.5228787452803685 0.3188109517495256 1.1358868078231543 6.071249488141243 0.6732111889461193 0.11236462384496157 38.16850708515905 0.5448257917047847 0.11379511518251328 109.69166848620648 0.029999999999997865 1.5228787452803685 4.935362680318089 NFTKPQDGDVIAPLIT(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 2 NFTKPQDGDVIAPLITPQK 19 1 Q9Y3Z3-3;Q9Y3Z3-4;Q9Y3Z3 Q9Y3Z3-3 SAMHD1 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 1 NFTKPQDGDVIAPLIT(1)PQK;NFTKPQDGDVIAPLIT(1)PQK 108.49 0.00013153 5860900.0 81477.0 112761.0 63279.0 69991.0 75449.0 106800.0 81276.0 91407.0 80019.0 74412.0 True False 107384.99117311962 149208.7880884614 62439.87911423589 53855.656300170485 64974.20869453929 100121.7791167381 88509.40654752516 77282.14847389924 84248.64097797367 71806.85852925021 1.4954698391293195 2.0779183373922683 0.8695531373065328 0.7500071358536402 0.9048468353210624 1.3943205588913756 1.2326037980267752 1.0762502364926423 1.1732673271544856 1.0 16.13183402712953 -5.266468911458128 24.990471277359436 1.0557348353706302 1.7866941027997925 0.6420717241719437 0.21995172836810256 243.39076993861644 1209352.8664861633 0.06099252807125814 0.1336072699838061 5.414160032257936e-06 5.266468911458128 0.7309592674291623 NFTKPQDGDVIAPLIT(ph)PQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NFTKPQDGDVIAPLITPQK 19 1 Q9Y3Z3-3;Q9Y3Z3-4;Q9Y3Z3 Q9Y3Z3-3 SAMHD1 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 1 NFTKPQDGDVIAPLIT(1)PQK;NFTKPQDGDVIAPLIT(1)PQK 112.26 8.0063e-05 7079700.0 125314.0 219005.0 129930.0 135610.0 143238.0 100852.0 128976.0 104594.0 98873.0 101159.0 True False 146527.18513568016 240746.3690463783 133028.02396226872 128012.21135355177 115171.5421425865 95563.14358020072 116758.45957462264 101848.51832650344 100318.83057566138 119498.32592579667 1.2261860908969324 2.014642190015879 1.113220816539919 1.071246901258197 0.9637920970884821 0.7997027811045765 0.9770719269082031 0.852300796161337 0.8394998825168067 1.0 16.866630881802095 -5.4534805867779745 5.34231288222616 0.9314971356859176 1.620426329220626 0.6656228981223888 0.19304716871345828 0.11221770464675164 6.008348064538499 0.04835916852972546 0.1016855163178617 3.5198115594044225e-06 5.4534805867779745 0.6889291935347084 NFTKPQDGDVIAPLIT(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 2 NFTKPQDGDVIAPLITPQK 19 1 Q9Y3Z3-3;Q9Y3Z3-4;Q9Y3Z3 Q9Y3Z3-3 SAMHD1 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 1 NFTKPQDGDVIAPLIT(1)PQK;NFTKPQDGDVIAPLIT(1)PQK 122.6 2.2719e-05 7143200.0 27225.0 56958.0 49041.0 50155.0 75611.0 54988.0 75850.0 82645.0 46491.0 67588.0 True False 26836.766507546472 56826.11725048907 45009.038283734444 53843.56601217527 71163.7096369456 52636.29142328873 79777.14186309966 86484.9884104059 41254.69400806629 79270.49574465083 0.33854672227601673 0.7168634019085681 0.5677905488155301 0.6792384165934604 0.8977326175199014 0.6640086065923287 1.0063913580164916 1.0910110703608398 0.5204293680836499 1.0 16.274496378350065 -4.5683309464969435 0.4240902941027324 0.9110015330515514 2.6626963770416662e-17 0.4388118629827442 0.1732753881262113 6.256390164537293 0.7697492835342996 0.12958597546245712 2.996956533166333 2.701898644922795e-05 4.5683309464969435 -0.9110015330515514 NFTKPQDGDVIAPLIT(ph)PQKK ddPTM_PC-9_AZD4547_30min_R2 3 NFTKPQDGDVIAPLITPQKK 20 2 Q9Y3Z3-3;Q9Y3Z3-4;Q9Y3Z3 Q9Y3Z3-3 SAMHD1 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 1 NFTKPQDGDVIAPLIT(1)PQKK;NFTKPQDGDVIAPLIT(1)PQKK;NFTKPQDGDVIAPLIT(1)PQKK 106.11 0.00057315 131361000.0 258639.0 188711.0 254780.0 271548.0 239843.0 277157.0 351135.0 359643.0 288867.0 322397.0 True False 340880.8219746011 249708.14030526212 251401.4507297051 208946.80397477813 206544.93944153556 259826.3289761964 382385.3347613708 304068.43812397943 304135.9198863315 311109.97916000965 1.0956923429295713 0.8026362284471518 0.808079031757463 0.6716171706832743 0.6638968637367484 0.8351590960782486 1.2291001908514896 0.9773663928908927 0.9775832993447913 1.0 18.247065145920352 -7.084057307502225 8.7558104898183 1.0434135278038286 0.7954238902387611 0.436496143673056 0.12964432460248154 0.357975432071465 34.73389508609517 0.05140837079146391 0.03983784701033306 8.240293727128248e-08 7.084057307502225 -0.24798963756506742 NFTKPQDGDVIAPLIT(ph)PQKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NFTKPQDGDVIAPLITPQKK 20 2 Q9Y3Z3-3;Q9Y3Z3-4;Q9Y3Z3 Q9Y3Z3-3 SAMHD1 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 1 NFTKPQDGDVIAPLIT(1)PQKK;NFTKPQDGDVIAPLIT(1)PQKK;NFTKPQDGDVIAPLIT(1)PQKK 84.499 0.006572199999999999 51487900.0 238281.0 241670.0 227106.0 285079.0 340200.0 296928.0 319787.0 298681.0 250875.0 206811.0 True False 278617.2670357267 265661.400458611 232521.06834430093 269106.94786858815 273540.25214613456 281356.5729681299 289494.4603026142 290840.9402286781 254543.5722661296 244304.19718502482 1.1404522322828319 1.087420533579336 0.9517686188919633 1.1015240465344067 1.1196707027467387 1.1516649169766138 1.184975385762056 1.1904868748874113 1.041912399373761 1.0 17.898319123985516 -5.990781803800679 24.99635852592755 1.1279296822326712 1.0566364492436728 0.08976640377740519 0.0710873902170749 367.82286621659495 997389.1700112113 0.020043053264728102 0.029683104720476194 1.0214525482158485e-06 5.990781803800679 -0.07129323298899837 NFTKPQDGDVIAPLIT(ph)PQKK ddPTM_PC-9_Lapatinib_30min_R1 3 NFTKPQDGDVIAPLITPQKK 20 2 Q9Y3Z3-3;Q9Y3Z3-4;Q9Y3Z3 Q9Y3Z3-3 SAMHD1 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 1 NFTKPQDGDVIAPLIT(1)PQKK;NFTKPQDGDVIAPLIT(1)PQKK;NFTKPQDGDVIAPLIT(1)PQKK 118.54 0.00012082 105207400.0 173519.0 183372.0 190304.0 224081.0 167237.0 209317.0 138773.0 149118.0 215728.0 164956.0 True False 171044.58724051213 182947.4134003419 174657.93971468374 240560.66425230305 157400.4484605923 200364.99985175888 145957.9869184961 156046.56666202281 191430.44092345037 193468.42480994598 0.8840956213322048 0.945618974155915 0.9027723251805004 1.243410466015931 0.8135717681849888 1.0356470315431976 0.7544279489631354 0.8065738211044795 0.9894660646123644 1.0 17.56173860366338 -7.240826138385371 24.917682067459157 0.8714980833538915 0.9718509999724105 0.08658807196489815 0.12820981233434 1687.098825008836 2039400.5992496854 0.04816891418256074 0.03726547323731672 5.7434634492935575e-08 7.240826138385371 0.10035291661851908 NFTPPS(ph)PFANK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NFTPPSPFANK 11 0 K7EJT1;Q9NPG3-2;Q9NPG3 K7EJT1 UBN1 Ubinuclein-1 1 NFT(0.169)PPS(0.831)PFANK 96.37100000000001 0.0058324 3738600.0 40488.0 34439.0 38589.0 52034.0 60930.0 53121.0 44602.0 47937.0 44089.0 34017.0 True False 47341.818725548896 37857.876320578085 39509.108109597444 49118.7036765041 48991.20388966476 50335.24124582402 40376.975669483654 46678.70454344988 44733.718216806665 40184.01282157615 1.1781257122267659 0.9421128867510941 0.983204646211532 1.2223444157904162 1.2191715174687514 1.2526185841449198 1.0048019805479431 1.1616237718893647 1.1132217784080445 1.0 15.294334019994878 -4.450374394221035 22.44868676454062 1.1076853553622399 4.166718544352113 0.04149584068396861 0.1070571454580064 1947.7398516574817 650551.8066312607 0.02747402393059224 23696.512256455808 3.5450764544582084e-05 4.450374394221035 3.059033188989873 NFVFHT(ph)LSPVK ddPTM_PC-9_Lapatinib_30min_R1 1 NFVFHTLSPVK 11 0 E7ESG2;Q9HAW4-2;Q9HAW4-3;Q9HAW4 E7ESG2 CLSPN Claspin 1 NFVFHT(0.851)LS(0.149)PVK 107.11 0.0057457 7291300.0 14835.0 18636.0 17611.0 19623.0 19608.0 21533.0 20296.0 18030.0 21507.0 16516.0 True False 14623.45017959419 18592.84948699243 16163.091560425919 21066.140880409042 18454.695990811222 20612.083785874667 21346.827570909292 18867.73962175105 19084.65518124976 19370.768593813325 0.7549235906036613 0.9598405657961683 0.8344063108362215 1.0875222001845186 0.9527085051599511 1.064081876052032 1.1020124197718766 0.974031542959894 0.9852296303485374 1.0 14.24159357791417 -3.760620142460516 0.6488817721985196 1.0256534966984197 3.1274755550586204e-10 0.5603918722948886 0.06834746831955908 7.984300231313222 0.9389691168178188 0.02884298545105813 8.212222823775392 0.00017353211402806908 3.760620142460516 -1.025653496385672 NFVFHT(ph)LSPVKAEAAK ddPTM_PC-9_AZD4547_30min_R2 1 NFVFHTLSPVKAEAAK 16 1 E7ESG2;Q9HAW4-2;Q9HAW4-3;Q9HAW4 E7ESG2 CLSPN Claspin 1 NFVFHT(0.97)LS(0.03)PVKAEAAK 78.069 0.0072673 19784000.0 37242.0 27032.0 36126.0 51274.0 50552.0 40325.0 40100.0 32732.0 33467.0 47020.0 True False 49084.181318277915 35769.5653604286 35646.945635690914 39453.571475403194 43533.72739103704 37803.47137530395 43668.822316006626 27674.02150653309 35235.99729576537 45373.844111774146 1.081772600032823 0.7883300624102662 0.7856276304885709 0.869522348122259 0.9594454303628286 0.8331555792843712 0.9624228048307443 0.6099113277323555 0.7765706870452688 1.0 15.46957327080215 -7.729622000021794 24.9999497072598 0.7699300139894449 0.8875734548182388 0.11259849911697861 0.12271636675503482 336.1061367067962 264089.647288392 0.055642942334640386 0.032121884045935634 1.863708560215314e-08 7.729622000021794 0.11764344082879385 NFVFHT(ph)LSPVKAEAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NFVFHTLSPVKAEAAK 16 1 E7ESG2;Q9HAW4-2;Q9HAW4-3;Q9HAW4 E7ESG2 CLSPN Claspin 1 NFVFHT(0.858)LS(0.142)PVKAEAAK 74.96600000000001 0.0091696 14535000.0 17583.0 15893.0 18271.0 29860.0 25456.0 27950.0 24171.0 29606.0 29948.0 17355.0 True False 20559.454619920125 17470.752006822127 18706.64993315336 28187.041007426153 20468.079537424994 26484.25279683705 21881.347897114247 28828.87387014995 30385.93284395035 20501.324117895598 1.0028354511001456 0.8521767621620067 0.9124605720868698 1.3748888045149092 0.9983784178875751 1.2918313297490358 1.0673138852535884 1.4061957025002711 1.4821448931401695 1.0 14.323429471554807 -5.745319686205135 24.847927797704987 1.2344157569246232 0.9154593216074745 0.43134562680977695 0.16252477299202628 208.51542459706093 321416.26055684645 0.043880155851532585 0.07569290824950199 1.7975472450504206e-06 5.745319686205135 -0.3189564353171488 NFVFHTLS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 3 NFVFHTLSPVK 11 0 E7ESG2;Q9HAW4-2;Q9HAW4-3;Q9HAW4 E7ESG2 CLSPN Claspin 1 NFVFHT(0.06)LS(0.94)PVK;NFVFHT(0.164)LS(0.836)PVK;NFVFHT(0.026)LS(0.974)PVK 76.311 0.011762 56287800.0 97018.0 109123.0 122655.0 173944.0 153349.0 129527.0 122271.0 152385.0 115596.0 119585.0 True False 127867.70590023833 144394.87573342878 121028.5145586466 133843.89820801065 132059.1383464182 121427.6562139859 133152.8821296869 128837.39970894036 121706.1685660888 115398.36554884112 1.1080547397018348 1.251273144525736 1.0487888106822671 1.1598422349523023 1.1443761592145394 1.052247626181438 1.1538541425296998 1.116457751339739 1.0546611122891336 1.0 16.816263264873584 -14.52287873595172 0.09336254642080186 0.5752767107077259 1.2236636441816613 0.3723955661932107 0.05478689966159758 211.6516312376292 1.3585646216346343 17.472844366144823 1.1061710934907207 3.000000064439811e-15 14.52287873595172 0.6483869334739354 NFVFHTLS(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NFVFHTLSPVK 11 0 E7ESG2;Q9HAW4-2;Q9HAW4-3;Q9HAW4 E7ESG2 CLSPN Claspin 1 NFVFHT(0.011)LS(0.989)PVK;NFVFHT(0.022)LS(0.978)PVK 95.755 0.0034499 36750000.0 124758.0 176624.0 128301.0 117446.0 136773.0 103892.0 134375.0 100998.0 94303.0 96012.0 True False 145877.0653171812 194158.06345264937 131360.182424252 110865.88138506938 109973.31248319568 98443.72062858667 121646.02720924752 98346.9095162267 95682.0029712516 113418.21556942638 1.2861872723423855 1.7118772542652103 1.1581929918818274 0.9774962586781782 0.9696265448284894 0.8679709880316939 1.0725440053743807 0.8671174116297561 0.8436211281483443 1.0 16.79129283783204 -5.504382025210462 3.5982200772734334 0.9429904991880027 1.4980447946741937 0.7776412243733034 0.11769719973143421 0.09181264887191083 2.518937781656774 0.03063059339463907 0.06404893201474579 3.130530755332161e-06 5.504382025210462 0.555054295486191 NFVFHTLS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 2 NFVFHTLSPVK 11 0 E7ESG2;Q9HAW4-2;Q9HAW4-3;Q9HAW4 E7ESG2 CLSPN Claspin 1 NFVFHT(0.008)LS(0.992)PVK;NFVFHT(0.037)LS(0.963)PVK 75.02 0.012576 42242000.0 81841.0 126962.0 120964.0 136741.0 152987.0 124037.0 139759.0 128915.0 113383.0 131950.0 True False 80673.93233219854 126668.02728952224 111018.80685454333 146797.38929460393 143988.6054440146 118732.22665436946 146995.0371739611 134904.8615273455 100612.61256407872 154757.38168767688 0.5212929519252941 0.8184942515062508 0.717373256408509 0.94856469974959 0.9304151044284579 0.7672152717987212 0.9498418464498104 0.8717184282660152 0.6501312665468181 1.0 17.239648699838988 -4.355118569163724 1.2981522578678322 0.8611279663657204 9.921533839782841e-15 0.4669989412145794 0.10629813883167771 3.277477120436022 2.3048073145675367 0.03018083292227291 4.9059136342831415 4.4144990819287994e-05 4.355118569163724 -0.8611279663657105 NFVFHTLS(ph)PVKAEAAK ddPTM_PC-9_Lapatinib_30min_R1 1 NFVFHTLSPVKAEAAK 16 1 E7ESG2;Q9HAW4-2;Q9HAW4-3;Q9HAW4 E7ESG2 CLSPN Claspin 1 NFVFHT(0.275)LS(0.725)PVKAEAAK 48.131 0.045725 16016000.0 76466.0 45865.0 50313.0 56101.0 51924.0 46706.0 43469.0 40052.0 43863.0 37860.0 True False 75375.58081785287 45758.80241043721 46176.459353796425 60226.854687449784 48869.93240651173 44708.493257003734 45719.612124549494 41912.96213701462 38922.687042133155 44404.050554721034 1.6974933564892751 1.0305096458271674 1.039915475658942 1.3563369542882044 1.1005737493764718 1.006856192137416 1.0296270622475587 0.9438995229807574 0.8765571283675359 1.0 15.43840366532906 -4.760340443754944 24.982592969437448 1.0509385924989374 1.697494130872155 0.7291272754616009 0.11963658442715266 15.633261230627072 355235.6585317542 0.032480578505555 0.19370933676790644 1.736439099237054e-05 4.760340443754944 0.6465555383732176 NFYES(ph)DDDQKEK ddPTM_PC-9_Lapatinib_30min_R1 2 NFYESDDDQKEK 12 1 O00203-3;O00203 O00203-3 AP3B1 AP-3 complex subunit beta-1 1 NFYES(1)DDDQKEK;NFYES(1)DDDQKEK 172.85 0.00082932 18030700.0 41990.0 60455.0 35831.0 45372.0 46635.0 43200.0 49371.0 53344.0 41867.0 48765.0 True False 41391.21489997706 60315.020161844164 32885.11349165979 48708.80823655503 43892.02098793766 41352.436704118576 51927.18880584172 55822.55698184629 37151.497580944946 57193.96527472193 0.7236989899399539 1.054569653846009 0.5749752326788584 0.8516424416910101 0.7674239891762962 0.7230209779211646 0.9079137730076573 0.9760218007915992 0.6495702370432572 1.0 15.803575311036868 -7.276947246543731 24.44564019597337 0.8813782732991791 0.7879365960012725 0.10481584106167197 0.14378214623660102 1614.352947743868 2544753.003206639 0.05765557269424327 0.03903640971643177 5.285094455603411e-08 7.276947246543731 -0.09344167729790653 NFYQEHPDLAR ddPTM_PC-9_AZD4547_30min_R2 2 NFYQEHPDLAR 11 0 P17844-2;P17844;J3KTA4;J3QRQ7;J3QR02;J3KRX8;X6RLV5;J3KTQ4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 ; 123.26 0.00049401 26569000.0 81331.0 67135.0 76810.0 119624.0 101978.0 101934.0 73882.0 90328.0 80788.0 99687.0 False True 107192.56621010821 88835.07585352074 75791.44921323763 92046.53497237645 87820.11496841224 95560.0508659696 80457.35487160091 76369.88313094602 85058.28874802908 96196.9884723611 1.1143027231138978 0.923470446052939 0.7878775668223096 0.9568546420642146 0.9129195868085239 0.9933788196854572 0.836381223043355 0.7938905816463089 0.8842094757723903 1.0 16.553704109469955 -7.275754617095896 24.736057293503873 0.8614445327975406 0.9385242561618594 0.1065233980387067 0.09095455300293322 1495.919198902045 2584867.2156226933 0.038291261890253586 0.02594926406823184 5.2996279625277286e-08 7.275754617095896 0.07707972336431879 NFYQEHPDLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NFYQEHPDLAR 11 0 P17844-2;P17844;J3KTA4;J3QRQ7;J3QR02;J3KRX8;X6RLV5;J3KTQ4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 ; 117.86 0.00094054 17037500.0 77188.0 77241.0 80665.0 89026.0 94576.0 90478.0 87421.0 85022.0 89944.0 68316.0 False True 90254.40386750817 84908.97601201478 82588.35952371615 84038.16184618638 76044.51171949657 85733.17440258402 79139.85000676935 82790.2625882554 91259.26084266965 80701.15001084148 1.1183781625835976 1.0521408431058048 1.023385162573534 1.0413502389358344 0.9422977455622463 1.062353812691226 0.9806533115840063 1.0258870236314261 1.1308297444387074 1.0 16.3003016119511 -4.718567326197999 1.9208588336140218 1.0237352042422572 1.1583532248594728 0.2587116338286445 0.04726264166713299 1.3248254575931664 4.574197561070917 0.012557158291377483 0.3388877331531586 1.91175693285111e-05 4.718567326197999 0.13461802061721562 NFYQEHPDLAR ddPTM_PC-9_Lapatinib_30min_R1 2 NFYQEHPDLAR 11 0 P17844-2;P17844;J3KTA4;J3QRQ7;J3QR02;J3KRX8;X6RLV5;J3KTQ4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 ; 108.98 0.001777 34446000.0 109065.0 109299.0 127899.0 102824.0 110878.0 104136.0 103673.0 108418.0 114935.0 100873.0 False True 107509.71309992876 109045.92488081052 117383.63792441746 110386.01997080864 104356.37403453518 99682.34603287248 109040.68066411515 113455.49607936827 101989.8099807941 118308.76364517606 0.9087214656588323 0.921706233088987 0.9921804125725362 0.9330333321872182 0.8820679958038783 0.8425609647298257 0.921661906561232 0.958977953819521 0.8620647096497035 1.0 16.852197418775148 -10.956857288073605 3.0665600662539885 1.0015522758043356 0.9153268740931935 0.27651041738871396 0.04181835853861599 59394117.60419313 71849485.642516 798149.9163194714 0.011500712795928469 1.1044414867691436e-11 10.956857288073605 -0.08622540171114212 NGDECAYHHPIS(ph)PCK ddPTM_PC-9_AZD4547_30min_R2 2 NGDECAYHHPISPCK 15 0 Q6PJT7;Q6PJT7-2;Q6PJT7-9;Q6PJT7-5;H0YJA2;Q6PJT7-11;Q6PJT7-3;Q6PJT7-4;G3V256;Q6PJT7-10;G3V5I6;G3V411;Q6PJT7-6;Q6PJT7-8;H0YJ51 Q6PJT7 ZC3H14 Zinc finger CCCH domain-containing protein 14 1 NGDECAYHHPIS(1)PCK;NGDECAYHHPIS(1)PCK 78.917 0.0098418 67033000.0 145956.0 148170.0 137979.0 165925.0 160889.0 159260.0 180984.0 163350.0 146168.0 164117.0 True False 192366.97192660396 196063.05487772677 136149.30830612307 127673.55476569537 138552.33949629188 149301.4470237052 197091.22538753488 138108.01090957408 153894.14207211373 158371.3137833267 1.2146579284540626 1.2379960119922186 0.8596841502015552 0.8061659129782177 0.8748575495550296 0.9427303686320977 1.2444881631605471 0.8720519367448353 0.9717299073660628 1.0 17.272951514333883 -5.252032372998019 24.67342306021832 0.9448363536183191 1.2263270234850758 0.4898110826700621 0.11424065539870319 491.71312990015826 1289694.835467583 0.03136459474118255 0.08057289461115436 5.597158778326854e-06 5.252032372998019 0.28149066986675675 NGDECAYHHPIS(ph)PCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NGDECAYHHPISPCK 15 0 Q6PJT7;Q6PJT7-2;Q6PJT7-9;Q6PJT7-5;H0YJA2;Q6PJT7-11;Q6PJT7-3;Q6PJT7-4;G3V256;Q6PJT7-10;G3V5I6;G3V411;Q6PJT7-6;Q6PJT7-8;H0YJ51 Q6PJT7 ZC3H14 Zinc finger CCCH domain-containing protein 14 1 NGDECAYHHPIS(1)PCK;NGDECAYHHPIS(1)PCK;NGDECAY(0.003)HHPIS(0.997)PCK;NGDECAYHHPIS(1)PCK 87.24 0.0045087 61299900.0 238189.0 308844.0 224145.0 261657.0 282288.0 237570.0 274137.0 253215.0 244122.0 203923.0 True False 278509.6932528102 339503.9912411101 229489.4668746464 246997.20659344018 226975.69282136348 225111.41098191697 248168.75877999337 246568.37455346962 247691.8224165505 240892.6256464205 1.1561569911301628 1.4093581749548043 0.952662898080942 1.0253415019685157 0.9422276510635733 0.9344885937369166 1.0302048811749542 1.023561322775318 1.028225010009687 1.0 17.87803070401909 -5.272231669073381 24.998138236136747 0.9916414035663976 1.282757586084979 0.7530372847462469 0.06658293787991476 273.8295944997296 634270.9549822949 0.01649981539800471 0.0348804557174301 5.342792786284412e-06 5.272231669073381 0.2911161825185813 NGDECAYHHPIS(ph)PCK ddPTM_PC-9_Lapatinib_30min_R1 2 NGDECAYHHPISPCK 15 0 Q6PJT7;Q6PJT7-2;Q6PJT7-9;Q6PJT7-5;H0YJA2;Q6PJT7-11;Q6PJT7-3;Q6PJT7-4;G3V256;Q6PJT7-10;G3V5I6;G3V411;Q6PJT7-6;Q6PJT7-8;H0YJ51 Q6PJT7 ZC3H14 Zinc finger CCCH domain-containing protein 14 1 NGDECAYHHPIS(1)PCK;NGDECAYHHPIS(1)PCK 80.238 0.008673700000000001 90671000.0 187195.0 156199.0 148602.0 147034.0 159410.0 160311.0 176853.0 175871.0 133242.0 142318.0 True False 184525.5649726416 155837.33081233772 136384.51718030806 157847.37085104545 150033.8172121184 153454.87223319337 186009.5829916251 184042.6087086512 118234.8828595379 166917.47667318478 1.1054897824386147 0.9336190189207008 0.8170775157794976 0.9456611374499861 0.8988502594361424 0.9193457467227926 1.114380511250009 1.1025963989917995 0.7083433395715374 1.0 17.348775490789393 NGES(ph)MSVGLLSQT(ph)Y(ph)LEVIK ddPTM_PC-9_Lapatinib_30min_R1 1 NGESMSVGLLSQTYLEVIK 19 0 Q14149 Q14149 MORC3 MORC family CW-type zinc finger protein 3 3 NGES(0.836)MS(0.162)VGLLS(0.044)QT(0.96)Y(0.999)LEVIK 52.172 0.014913 1001200.0 1163.9 2339.3 3469.6 2273.8 2571.6 1135.8 836.01 1014.7 2385.4 983.38 True False 1147.3025725668815 2333.883494576164 3184.342881043311 2441.0228371744424 2420.343543960125 1087.224481679118 879.2945071716539 1061.8466663444701 2116.731132624407 1153.3559227285157 0.9947515332931107 2.0235587719139225 2.7609368611122678 2.11645233623951 2.0985226643951096 0.9426617232840412 0.7623791492668546 0.9206582681193847 1.8352800648188607 1.0 10.171622078412113 -6.758796722133748 24.98076255892721 1.0666233642840106 2.0490898223338783 0.4645344542311428 0.48481930375862486 61.79884119184864 584179.1647835132 0.1707027440468403 0.16332869513379458 1.742622342333384e-07 6.758796722133748 0.9824664580498677 NGESAS(ph)PERDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NGESASPERDR 11 1 Q14676;Q14676-3 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 NGES(0.084)AS(0.916)PERDR 88.28200000000001 0.046135 0.0 5787.7 11182.0 8632.8 7376.0 7530.9 6355.1 7811.7 6068.5 5450.1 6335.9 True False 6767.443297714367 12292.075060736488 8838.638692076316 6962.74663331465 6055.274206017988 6021.827368485841 7071.719224189628 5909.208305107238 5529.79740192379 7484.548515043198 0.9041885805286023 1.6423268599342553 1.1809180840115514 0.930282784501994 0.8090366698602447 0.8045678849408976 0.9448424590977232 0.7895210102827601 0.7388284531537804 1.0 12.869699576930625 -5.747762891210794 3.2795897760156705 0.8433426575625501 1.3002589309677202 0.4875549138173946 0.18152804060017635 0.17190243454374207 3.8322246323280273 0.04895289567773433 0.0853137285098951 1.7874631975626667e-06 5.747762891210794 0.45691627340517005 NGESAS(ph)PERDR ddPTM_PC-9_Lapatinib_30min_R1 1 NGESASPERDR 11 1 Q14676;Q14676-3 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 NGES(0.063)AS(0.937)PERDR 96.059 0.028773000000000003 1213300.0 2984.8 9512.4 6604.9 7023.2 7654.9 8600.0 10098.0 9363.2 6554.5 7479.5 True False 2942.236204654719 9490.374622240113 6061.870617651304 7539.709556708391 7204.653832112449 8232.198047579162 10620.825030106533 9798.248454042126 5816.263188055119 8772.32160919271 0.3353999472125469 1.081854387588223 0.6910223869698229 0.859488501744779 0.8212938550454572 0.938428663964219 1.21071997850338 1.11695043690308 0.6630243904829171 1.0 13.098742989455408 -6.733207335986966 2.4991524669764806 1.013556868409341 0.7677596698974859 0.21873387587684268 0.21770657060690543 0.4569223056246299 5.8480386256214345 0.0797394227176229 0.07508394646148046 1.848385972661347e-07 6.733207335986966 -0.2457971985118551 NGHDGDTHQEDDGEKS(ph)D ddPTM_PC-9_AZD4547_30min_R2 2 NGHDGDTHQEDDGEKSD 17 1 K7EQH5;Q08117;Q08117-2 K7EQH5 AES Amino-terminal enhancer of split 1 NGHDGDTHQEDDGEKS(1)D;NGHDGDTHQEDDGEKS(1)D 128.41 1.5259e-05 5519400.0 31109.8 35730.0 21610.6 24445.8 28935.7 32371.1 28062.5 29381.9 28339.5 28270.2 True False 41002.0692759616 47279.023761768054 21324.02932388481 18810.19849384504 24918.47752153883 30346.929999680142 30560.00813573405 24841.602483893566 29837.468113764062 27280.468902779172 1.502982570500632 1.7330722551089124 0.7816591936113109 0.6895115535176439 0.9134182264367268 1.112404999629188 1.1202156474891374 0.9106002749594546 1.0937300315510485 1.0 14.735580821488528 -5.258639805988784 24.99975745269555 0.950384654567328 1.6180274630483482 0.7763332123974216 0.14284461751232294 113.12356813393183 1010162.109463873 0.04045579959012361 0.09766018687788129 5.512647133325124e-06 5.258639805988784 0.6676428084810202 NGHDGDTHQEDDGEKS(ph)D ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NGHDGDTHQEDDGEKSD 17 1 K7EQH5;Q08117;Q08117-2 K7EQH5 AES Amino-terminal enhancer of split 1 NGHDGDTHQEDDGEKS(1)D;NGHDGDTHQEDDGEKS(1)D 100.95 0.00052353 9400100.0 16648.3 23457.0 18134.3 22365.8 22410.4 18962.1 26233.0 20066.9 16616.1 19420.9 True False 19466.528371086628 25785.65593808762 18566.690486715725 21112.716736901933 18019.242994402473 17967.694095130733 23748.02032952704 19540.165137638054 16859.079027927186 22941.755434240196 0.8485195662940923 1.1239617653496101 0.809296853500811 0.9202746841853064 0.7854343598968476 0.7831874133011741 1.0351439931263284 0.8517292930633668 0.7348643863043403 1.0 14.485688165819433 -5.290529510286547 24.99791301272983 0.8619843809429079 0.9862407963614519 0.1618081255246171 0.11021526656167284 1041.6413645151915 895108.0682124983 0.0278503667788261 0.05799149679044676 5.122364626420436e-06 5.290529510286547 0.12425641541854404 NGISPT(ph)NPTK ddPTM_PC-9_AZD4547_30min_R2 1 NGISPTNPTK 10 0 Q9UJF2-2;Q9UJF2;A0A3B3ITG3;Q5VWQ8-2;Q5VWQ8 Q9UJF2-2;A0A3B3ITG3 RASAL2;DAB2IP Ras GTPase-activating protein nGAP;Disabled homolog 2-interacting protein 1 NGIS(0.29)PT(0.707)NPT(0.004)K 76.165 0.038452999999999994 0.0 21289.0 20278.0 20226.0 29097.0 30069.0 25025.0 22426.0 24612.0 26193.0 22902.0 True False 28058.45916129149 26832.46694209717 19957.790024566366 22389.136194168703 25894.438378720766 23460.182793973487 24421.87055508143 20808.780927495787 27577.508505930673 22100.20795082628 1.2696015903435172 1.2141273512810526 0.9030589245573224 1.0130735531532236 1.1716830192881795 1.0615367441868961 1.1050516180400172 0.9415649379316267 1.2478393220231943 1.0 14.43177232419848 -5.0558828461566945 10.219222915959147 1.0579483127191258 1.2558857488110586 0.3762074682311365 0.09711979134712469 0.5501200871351871 99.51006857398558 0.02393975588108709 0.06384087794042069 8.792596710237846e-06 5.0558828461566945 0.19793743609193282 NGLES(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 1 NGLESPTR 8 0 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 NGLES(0.957)PT(0.043)R 72.096 0.033615 13253000.0 58296.0 44439.0 59891.0 93394.0 88672.0 76404.0 61942.0 87448.0 62741.0 72865.0 True False 76832.915367873 58803.03769799076 59096.806207915746 71863.45622291611 76361.4233901338 71626.44580182804 67454.71800244605 73934.92095512983 66057.36117170993 70314.01852837994 1.0927111972253716 0.8362918082154108 0.8404697590148864 1.0220359713036569 1.0860056783600418 1.0186652292233644 0.9593352707500309 1.05149616680333 0.9394621805756707 1.0 16.101524728095647 -5.789251540218916 24.99618304969866 1.014437697515694 0.9144709875939301 0.21281514754917985 0.07667771136314044 279.5085130494811 251207.28075219368 0.021497499743670236 0.03189356912800072 1.6246075222869005e-06 5.789251540218916 -0.09996670992176382 NGLQSCPIKEDS(ph)FLQR ddPTM_PC-9_Lapatinib_30min_R1 2 NGLQSCPIKEDSFLQR 16 1 P00533;E9PFD7;Q504U8 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 NGLQSCPIKEDS(1)FLQR;NGLQS(0.001)CPIKEDS(0.999)FLQR 74.657 0.023799 5157200.0 79065.0 67488.0 37128.0 28740.1 32463.0 30866.1 28384.9 24529.5 38748.0 22526.3 True False 77937.5186012546 67331.73568245032 34075.47915822458 30853.74282816308 30553.59016471363 29546.028855393375 29854.531233617625 25669.23011934234 34383.79220547101 26419.940940592005 2.949950523224304 2.5485195380963477 1.2897636385655387 1.1678202800506232 1.1564594422605474 1.118323047043546 1.1299999231924347 0.9715854466541877 1.3014333484993987 1.0 14.689339621122446 -5.213021905116605 2.652244806665482 1.120100153744039 2.92490122367437 0.9816746415905636 0.08889398601449615 0.032170296666910146 0.4314115177793844 0.02348264579636061 0.08196553330651865 6.12319506532771e-06 5.213021905116605 1.804801069930331 up NGLS(ph)PPPCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NGLSPPPCK 9 0 H0YBR2;H0YBB3;Q6NXG1-2;Q6NXG1-4;Q6NXG1 H0YBR2 ESRP1 Epithelial splicing regulatory protein 1 1 NGLS(1)PPPCK 69.01 0.041517 16703000.0 54399.0 78428.0 67222.0 72566.0 71599.0 66745.0 72528.0 55743.0 51201.0 47599.0 True False 63607.67627077486 86213.81352740506 68824.82742085452 68500.36228214634 57569.68992772207 63244.77470214282 65657.62278275214 54279.80531459059 51949.717762224536 56228.32190652336 1.1312391000485358 1.5332809268384535 1.224024212126981 1.2182537191137341 1.0238557363214338 1.1247850292826442 1.1676966439066863 0.9653463499200264 0.923906600815657 1.0 15.779009370883747 -6.291861377957749 0.6091079169851158 0.9805120534538224 1.3630007698093163 0.5226946178493341 0.11528495857309994 0.7499475062663549 0.5854999425732988 0.08215080164344254 0.1556247025818692 5.106679735886849e-07 6.291861377957749 0.38248871635549386 NGLS(ph)PPPCK ddPTM_PC-9_Lapatinib_30min_R1 1 NGLSPPPCK 9 0 H0YBR2;H0YBB3;Q6NXG1-2;Q6NXG1-4;Q6NXG1 H0YBR2 ESRP1 Epithelial splicing regulatory protein 1 1 NGLS(1)PPPCK 74.962 0.026666000000000002 43154000.0 91751.0 121710.0 108170.0 113790.0 119810.0 141090.0 139980.0 107890.0 113290.0 113510.0 True False 90442.61391492732 121428.18797284011 99276.68014827481 122158.49619231233 112763.0113555228 135055.90959685404 147227.47947259957 112902.96327180922 100530.087203412 133130.0522574326 0.6793553550181074 0.912102007877495 0.7457120196745978 0.9175876830281366 0.8470139494685527 1.0144659850031263 1.1058921481372732 0.8480651915728958 0.755126926631244 1.0 17.022476750787014 -5.961439838498371 1.5083135036182083 0.9386346484892637 0.786083657287541 0.26637986368824396 0.10897645855689825 0.616587765550772 2.8446388080937512 0.03914433842212375 0.07095777382690685 1.0928490057725533e-06 5.961439838498371 -0.15255099120172266 NGNGGPGPYVGQAGTAT(ph)LPR ddPTM_PC-9_AZD4547_30min_R2 4 NGNGGPGPYVGQAGTATLPR 20 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 NGNGGPGPYVGQAGTAT(1)LPR;NGNGGPGPYVGQAGT(0.01)AT(0.99)LPR;NGNGGPGPYVGQAGT(0.003)AT(0.997)LPR;NGNGGPGPYVGQAGT(0.005)AT(0.995)LPR 272.51 6.031999999999999e-92 61408700.0 116883.0 98233.0 125893.0 149970.0 132455.0 135533.0 154107.0 118610.0 104782.0 138020.0 True False 154049.36268256983 129984.89619898587 124223.57656297513 115396.7335134027 114065.90958972592 127058.10008453995 167822.22445518273 100281.54988665199 110320.5626033073 133187.96181001852 1.1566312795018843 0.9759507873872147 0.9326937275319946 0.866420147475539 0.8564280738257065 0.9539758575611939 1.2600404884532064 0.7529325362730247 0.8283073117424108 1.0 17.02310416479012 -4.744975244674053 2.6595596488195086 0.9305033608130276 1.214826016182047 0.2152784385327846 0.12867677501619626 0.9119297101787343 7.833544719578299 0.03463279485816864 0.6080330428222179 1.798973455932091e-05 4.744975244674053 0.28432265536901935 NGNGGPGPYVGQAGTAT(ph)LPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 NGNGGPGPYVGQAGTATLPR 20 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 NGNGGPGPYVGQAGT(0.003)AT(0.997)LPR;NGNGGPGPYVGQAGT(0.001)AT(0.999)LPR;NGNGGPGPYVGQAGT(0.358)AT(0.642)LPR;NGNGGPGPYVGQAGT(0.023)AT(0.977)LPR;NGNGGPGPYVGQAGT(0.169)AT(0.831)LPR;NGNGGPGPYVGQAGTAT(1)LPR 204.51 3.4354e-28 72932800.0 146354.9 129955.8 109122.7 136669.3 132601.3 122315.3 129648.4 110173.3 105946.2 99731.0 True False 171129.89392896224 142856.95297603804 111724.59901814413 129012.16220884895 106619.02715139679 115900.87034422041 117367.1649788683 107281.36761326072 107495.46274448145 117811.44082983844 1.4525744929657094 1.2125898127531962 0.948334034718361 1.095073290846076 0.9049972260791932 0.9837828102927834 0.9962289243910375 0.9106192646282386 0.9124365340692427 1.0 16.84612012249316 -4.720009861795571 1.2805836069058774 0.960390320023678 1.7368150450088513 0.8817924088312027 0.05642382162402335 0.4768472627486884 0.6182129545000538 0.016334879131356422 0.5078689036485018 1.9054174499699816e-05 4.720009861795571 0.7764247249851733 NGNGGPGPYVGQAGTAT(ph)LPR ddPTM_PC-9_Lapatinib_30min_R1 4 NGNGGPGPYVGQAGTATLPR 20 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 NGNGGPGPYVGQAGTAT(1)LPR;NGNGGPGPYVGQAGT(0.038)AT(0.962)LPR;NGNGGPGPYVGQAGTAT(1)LPR;NGNGGPGPY(0.001)VGQAGT(0.036)AT(0.963)LPR 243.09 7.716e-54 85240000.0 232604.0 156119.0 111720.0 102707.0 92167.0 97425.0 69471.4 59057.3 93606.0 50630.299999999996 True False 229287.0243056501 155757.5160474227 102534.81285167139 110260.41540050818 86745.91826729383 93258.35985876739 73068.28916582908 61801.31775727337 83063.10656512121 59381.67989436588 3.8612417956772016 2.622989385354201 1.7267078505369107 1.8568086250953244 1.4608195393193022 1.5704904277660174 1.2304853836370127 1.0407472113825642 1.3988002143570584 1.0 15.857730286969494 -1.5228787452803385 0.5344679684898441 1.2164143677246697 108.4692027710366 0.9570666824864625 0.17084920064963285 22.910190811003208 0.22024479850588222 0.08835192473554686 2803.041892185351 0.029999999999999933 1.5228787452803385 107.25278840331194 up NGNTNSLNLS(ph)SPNPMENK ddPTM_PC-9_AZD4547_30min_R2 1 NGNTNSLNLSSPNPMENK 18 0 Q9UPQ9-1;Q9UPQ9;H0Y720 Q9UPQ9-1 TNRC6B Trinucleotide repeat-containing gene 6B protein 1 NGNTNSLNLS(0.643)S(0.356)PNPMENK 138.91 3.1902e-08 0.0 12236.0 12825.0 11898.0 18380.0 16219.0 14198.0 14741.0 15372.0 13027.0 13547.0 True False 16126.793475389304 16970.43044345578 11740.22474598491 14142.774968169255 13967.271810318685 13310.19681553788 16052.920442899098 12996.610613418867 13715.580624852411 13072.723653385889 1.2336215392430787 1.2981556784504025 0.8980702917975432 1.0818537393702359 1.0684285984046717 1.0181655459450094 1.2279706102975203 0.9941777213390947 1.0491754425865203 1.0 13.67427213214924 -5.239681026320765 24.992532266786974 1.0501472120931719 1.265888658498826 0.5508874354239751 0.08052422552296302 600.9871769816097 690315.9398008368 0.020079854170620276 0.053033381484142966 5.758627325225808e-06 5.239681026320765 0.21574144640565418 NGNTNSLNLS(ph)SPNPMENK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NGNTNSLNLSSPNPMENK 18 0 Q9UPQ9-1;Q9UPQ9;H0Y720 Q9UPQ9-1 TNRC6B Trinucleotide repeat-containing gene 6B protein 1 NGNT(0.003)NS(0.084)LNLS(0.616)S(0.298)PNPMENK;NGNTNSLNLS(0.693)S(0.307)PNPMENK;NGNT(0.001)NS(0.007)LNLS(0.64)S(0.352)PNPMENK 177.04 9.4325e-33 4886400.0 28486.6 35410.3 28398.9 44667.8 58287.0 64368.0 74312.0 70483.0 61806.0 59167.0 True False 33308.818744003656 38925.60056548002 29076.037479427996 42165.20798096147 46866.080766730476 60992.4287666121 67272.62938771064 68632.89593291142 62709.79582453571 69893.50873428577 0.4765652683231833 0.5569272636385092 0.41600483372449365 0.6032778829470558 0.6705355277684127 0.872647973626379 0.9625018203544633 0.9819638071660298 0.8972191689923539 1.0 16.092870853008264 -6.6039904022876215 1.402428490996417 0.9653588552383026 0.493112243085327 0.9500318121852288 0.047378474726016986 0.07942378640965735 0.3243285860904111 0.019876968667145157 0.020604897888783738 2.4889123215155407e-07 6.6039904022876215 -0.4722466121529756 NGNTNSLNLS(ph)SPNPMENK ddPTM_PC-9_Lapatinib_30min_R1 1 NGNTNSLNLSSPNPMENK 18 0 Q9UPQ9-1;Q9UPQ9;H0Y720 Q9UPQ9-1 TNRC6B Trinucleotide repeat-containing gene 6B protein 1 NGNTNSLNLS(0.674)S(0.326)PNPMENK 180.74 5.0895e-33 0.0 11701.0 7980.7 4977.2 7632.7 10403.0 12816.0 12737.0 14810.0 13530.0 12893.0 True False 11534.141594299399 7962.221179482745 4567.993828547605 8194.034219940784 9791.115993084919 12267.88955555518 13396.459537380355 15498.126666563128 12006.108922783706 15121.537871157376 0.7627624711570818 0.5265483740691337 0.3020852685400826 0.5418783651344072 0.6474947241814846 0.8112858401098736 0.8859191208939526 1.0249041333371292 0.7939740669951303 1.0 13.884317249681704 -6.759611193720831 1.7379794198498997 0.9292862415663764 0.5171774177433889 0.6937301787418886 0.11903629065358026 0.2057609830522712 1.2857761415006934 0.0520856293834177 0.04759895720291709 1.739357308146796e-07 6.759611193720831 -0.4121088238229875 NGPSS(ph)SPFSSPASSR ddPTM_PC-9_AZD4547_30min_R2 1 NGPSSSPFSSPASSR 15 0 A8CG34-2;A8CG34;A6NF01;C9JFL1;Q96HA1;Q96HA1-2;Q96HA1-3 A8CG34-2;Q96HA1 POM121C;POM121B;POM121 Nuclear envelope pore membrane protein POM 121C;Putative nuclear envelope pore membrane protein POM 121B;Nuclear envelope pore membrane protein POM 121 1 NGPS(0.001)S(0.906)S(0.093)PFSSPASSR 210.91 2.0649e-13 10386000.0 18712.0 18004.0 21552.0 31316.0 32770.0 22474.0 21403.0 25148.0 17898.0 25784.0 True False 24662.02676622137 23823.440912590864 21266.206398173348 24096.58002737695 28220.451151374506 21068.69722724317 23307.825536895005 21261.954443550476 18844.051740508818 24881.310008038796 0.9911868289191132 0.9574833843111095 0.8547060581336972 0.968461066543188 1.134202786841082 0.8467680045960673 0.9367603847773521 0.8545351686338477 0.7573577007971274 1.0 14.60277482532131 NGPSS(ph)SPFSSPASSR ddPTM_PC-9_Lapatinib_30min_R1 3 NGPSSSPFSSPASSR 15 0 A8CG34-2;A8CG34;A6NF01;C9JFL1;Q96HA1;Q96HA1-2;Q96HA1-3 A8CG34-2;Q96HA1 POM121C;POM121B;POM121 Nuclear envelope pore membrane protein POM 121C;Putative nuclear envelope pore membrane protein POM 121B;Nuclear envelope pore membrane protein POM 121 1 NGPS(0.071)S(0.684)S(0.219)PFS(0.015)S(0.005)PAS(0.003)S(0.002)R;NGPS(0.001)S(0.987)S(0.012)PFSSPASSR;NGPSS(0.5)S(0.5)PFSSPASSR 252.37 1.2715999999999999e-41 25304000.0 86365.8 74527.5 51085.0 50554.7 54257.9 58497.0 52863.0 50459.5 73283.0 40029.6 True False 85134.20785445214 74354.93615270602 46884.98849380259 54272.661283535366 51066.55699713566 55995.219673167245 55599.98747935445 52804.03258146128 65029.09683579889 46948.66302391077 1.8133467999097999 1.5837498101881484 0.9986437413547699 1.1560001454332047 1.0877105695454556 1.1926903998235072 1.1842720090034853 1.1247185581103427 1.3851107283434212 1.0 15.518796453802562 -5.0894537629019805 3.9623866982673275 1.1487852967929464 1.7752411468763727 0.8201717251244547 0.10653052937831703 0.081544098252654 2.2732779251777195 0.02680738823034725 0.08738701472239935 8.138535029597975e-06 5.0894537629019805 0.6264558500834263 NGPSSS(ph)PFSSPASSR ddPTM_PC-9_AZD4547_30min_R2 1 NGPSSSPFSSPASSR 15 0 A8CG34-2;A8CG34;A6NF01;C9JFL1;Q96HA1;Q96HA1-2;Q96HA1-3 A8CG34-2;Q96HA1 POM121C;POM121B;POM121 Nuclear envelope pore membrane protein POM 121C;Putative nuclear envelope pore membrane protein POM 121B;Nuclear envelope pore membrane protein POM 121 1 NGPS(0.002)S(0.226)S(0.772)PFSSPASSR 229.69 1.1238e-24 10703000.0 17093.0 17056.0 23931.0 29920.0 28281.0 21976.0 20079.0 26571.0 22499.0 20974.0 True False 22528.21844351334 22569.01845174128 23613.659303762375 23022.406259391955 24354.671315594198 20601.837245968483 21865.992101822874 22465.062490837427 23688.25120738115 20239.706643988742 1.1130704036268377 1.115086243527366 1.1666996819232904 1.137487151585257 1.2033114779767629 1.0178920874867174 1.0803512366280834 1.1099500050070945 1.170385106071517 1.0 14.304900759189886 -6.757242883674335 24.99999860669479 1.0828772875645607 1.1459020984339985 0.3303115468082577 0.05031440554305905 150.00579950993168 893634.7545807507 0.017116096150089355 0.016527453740065506 1.7488683423924965e-07 6.757242883674335 0.06302481086943779 NGPSSS(ph)PFSSPASSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NGPSSSPFSSPASSR 15 0 A8CG34-2;A8CG34;A6NF01;C9JFL1;Q96HA1;Q96HA1-2;Q96HA1-3 A8CG34-2;Q96HA1 POM121C;POM121B;POM121 Nuclear envelope pore membrane protein POM 121C;Putative nuclear envelope pore membrane protein POM 121B;Nuclear envelope pore membrane protein POM 121 1 NGPS(0.002)S(0.226)S(0.772)PFSSPASSR;NGPSS(0.008)S(0.992)PFSSPASSR;NGPS(0.001)S(0.003)S(0.996)PFSSPASSR 254.89 6.876099999999999e-50 19841000.0 47411.8 47648.0 44964.0 55087.0 84821.0 60097.0 61473.0 68336.0 62652.0 52159.0 True False 55437.68131426543 52378.17854533828 46036.11228691958 52000.65398446365 68200.93394264333 56945.4075252779 55649.83241402115 66542.25240797685 63568.16697406093 61615.01380958315 0.8997430640134508 0.8500879137544194 0.747157380004668 0.8439607616605913 1.1068882359324548 0.9242131747509408 0.9031862361664484 1.079968148893401 1.0316993057976722 1.0 15.910994316661405 -6.152896242305521 7.488197007803171 1.0020020857776717 0.828245143667759 0.6071470071144779 0.06784163727777624 0.19805091907300923 12.176786435082768 0.020956652906255275 0.027137961177744092 7.032403116057487e-07 6.152896242305521 -0.17375694210991266 NGQAEAEEATEQTHIS(ph)PNAIFK ddPTM_PC-9_AZD4547_30min_R2 2 NGQAEAEEATEQTHISPNAIFK 22 0 P48436 P48436 SOX9 Transcription factor SOX-9 1 NGQAEAEEATEQTHIS(1)PNAIFK;NGQAEAEEATEQTHIS(1)PNAIFK 151.63 1.3339e-05 11983700.0 20512.0 14998.0 24833.0 32465.0 29721.0 31806.0 32064.0 28981.0 26542.0 29164.0 True False 27034.389323895506 19845.810198124746 24503.69819440603 24980.695829250006 25594.75217180352 29817.165792012835 34917.6338838014 24502.652367128037 27944.95593343307 28142.977236830724 0.9606087194113774 0.7051780638244814 0.8706860680801757 0.8876351502909848 0.9094543180849984 1.0594886795769105 1.240722813011577 0.8706489068633936 0.9929637400573773 1.0 14.780487338458185 -6.569675257163928 2.982487003182862 1.037059755249458 0.8479217595061139 0.3921864900799007 0.10431347318768128 0.2718444589378053 4.937718912995003 0.03749421690956636 0.03878572948833513 2.693548146372138e-07 6.569675257163928 -0.1891379957433441 NGQAEAEEATEQTHIS(ph)PNAIFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NGQAEAEEATEQTHISPNAIFK 22 0 P48436 P48436 SOX9 Transcription factor SOX-9 1 NGQAEAEEATEQTHIS(1)PNAIFK;NGQAEAEEATEQT(0.001)HIS(0.999)PNAIFK 121.97 4.0018000000000003e-07 7413600.0 37488.0 39032.0 36016.0 50429.0 50487.0 42977.0 48013.0 51667.0 43291.0 35267.0 True False 43833.97797824976 42906.839006498536 36874.75803144062 47603.6266230239 40594.43477396199 40723.21046331546 43464.86105598226 50310.795995711596 43924.04897647436 41660.62792658163 1.052167961930344 1.0299134012601323 0.8851224733440138 1.1426526433282667 0.9744076552446933 0.9774987197764236 1.043307871705156 1.2076341260235954 1.054329979228387 1.0 15.346396964000938 -7.533177920566505 24.985355790458577 1.1036834460784233 1.0099246308277732 0.15264017890558335 0.07853726159283574 317.7007251261905 770717.2201517775 0.03536028356832188 0.020442503554924267 2.929692770902947e-08 7.533177920566505 -0.09375881525065011 NGQAEAEEATEQTHIS(ph)PNAIFK ddPTM_PC-9_Lapatinib_30min_R1 2 NGQAEAEEATEQTHISPNAIFK 22 0 P48436 P48436 SOX9 Transcription factor SOX-9 1 NGQAEAEEATEQTHIS(1)PNAIFK;NGQAEAEEATEQTHIS(1)PNAIFK 137.99 1.1524e-05 9426800.0 37940.0 27358.0 29255.0 28133.0 28883.0 27203.0 25314.0 22201.6 28435.0 26839.0 True False 37398.96864265612 27294.654231870496 26849.76682756573 30201.994668936833 27184.15872616284 26039.591103290226 26624.63505764673 23233.16738692558 25232.3508661755 31478.085389280463 1.1880954060627826 0.8671002030245909 0.8529669608402912 0.9594609804070806 0.8635899671147129 0.8272291907613206 0.8458149448540945 0.7380743491736443 0.801584675628592 1.0 14.942060173146054 -4.761200971649399 5.831113651041808 0.8539595432464938 1.2017260189335612 0.6585284917705997 0.07036023665215967 0.08556905573335404 10.485810986908136 0.017927853863923062 0.11941477233913657 1.7330018580682923e-05 4.761200971649399 0.3477664756870674 NGQDLGVAFK ddPTM_PC-9_Lapatinib_30min_R1 2 NGQDLGVAFK 10 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PRZ7;A0A1W2PQ74;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 ; 100.88 0.017591 10122100.0 72551.0 66187.0 72370.0 70134.0 65104.0 60981.0 70386.0 65109.0 65096.0 63993.0 False True 71516.40943577599 66033.7480680172 66420.0179562788 75291.8883201655 61274.71071938874 58372.98478365407 74030.24267865703 68134.20183209048 57764.202988730794 75054.10478468736 0.9528647319282512 0.8798152780244672 0.8849618304931125 1.003168161636999 0.8164071891227207 0.7777454004829248 0.9863583463027432 0.9078011392921351 0.7696341613086021 1.0 16.19564335599995 -4.756021637429218 23.763670766142415 0.8891911419664478 0.9528649170888043 0.04682710534018375 0.08196004279106842 329.0633059530932 1443057.993191956 0.020129449672502055 0.16495617879896976 1.7537931221456024e-05 4.756021637429218 0.0636737751223565 NGS(ph)EADIDEGLYSR ddPTM_PC-9_AZD4547_30min_R2 4 NGSEADIDEGLYSR 14 0 P22314;P22314-2;Q5JRR9;Q5JRS2;Q5JRS3;Q5JRS0;Q5JRS1 P22314;Q5JRS0 UBA1 Ubiquitin-like modifier-activating enzyme 1 1 NGS(1)EADIDEGLYSR;NGS(1)EADIDEGLYSR;NGS(0.999)EADIDEGLY(0.001)SR;NGS(1)EADIDEGLYSR 165.16 6.692e-05 26404400.0 54163.0 46535.0 49998.0 61338.0 53513.0 58779.0 53090.0 59651.0 54811.0 52063.0 True False 71385.70733961347 61576.52870847681 49334.99385188717 47197.47176265318 46083.643651617436 55103.53983804067 57814.90715104219 50433.308593614944 57708.19756112573 50240.2902167439 1.4208856483838999 1.2256403862881113 0.9819806700767223 0.9394346959190808 0.9172646784643542 1.0967997915680026 1.1507677782437222 1.0038419040980522 1.148643793898566 1.0 15.616557177637427 -4.9797619170974965 2.870494242177413 1.0300675588666002 1.4240425457667043 0.7228694717841873 0.07714315429446769 0.16542281929538583 2.494746756181897 0.0220487239774344 0.12356361513481809 1.04770274772813e-05 4.9797619170974965 0.39397498690010413 NGS(ph)EADIDEGLYSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NGSEADIDEGLYSR 14 0 P22314;P22314-2;Q5JRR9;Q5JRS2;Q5JRS3;Q5JRS0;Q5JRS1 P22314;Q5JRS0 UBA1 Ubiquitin-like modifier-activating enzyme 1 1 NGS(1)EADIDEGLYSR;NGS(1)EADIDEGLYSR;NGS(1)EADIDEGLYSR;NGS(1)EADIDEGLYSR 183.73 7.1012e-06 14045300.0 51380.8 58686.4 46118.5 60515.0 65121.0 52663.0 61792.7 58700.0 54455.0 45871.5 True False 60078.55462294213 64512.39794709407 47218.13994538524 57124.540742277124 52361.00752500998 49901.25957208694 55939.24811559353 57159.18719779107 55251.301356261356 54187.63983140583 1.1087132565630229 1.190537143669879 0.8713821102431326 1.0541987235467143 0.9662906095914298 0.9208974542413156 1.0323248676199495 1.0548381028520641 1.0196292277752805 1.0 15.725676190768636 -5.2419068607496415 24.994386879191794 0.9924011751268697 1.1496252197246235 0.5458832747065883 0.058222044253972656 614.3127416183293 786090.1444680757 0.014708509556184841 0.0387959451656558 5.729188865971549e-06 5.2419068607496415 0.15722404459775385 NGS(ph)EADIDEGLYSR ddPTM_PC-9_Lapatinib_30min_R1 4 NGSEADIDEGLYSR 14 0 P22314;P22314-2;Q5JRR9;Q5JRS2;Q5JRS3;Q5JRS0;Q5JRS1 P22314;Q5JRS0 UBA1 Ubiquitin-like modifier-activating enzyme 1 1 NGS(1)EADIDEGLYSR;NGS(1)EADIDEGLYSR;NGS(1)EADIDEGLYSR;NGS(0.999)EADIDEGLY(0.001)SR 197.51 1.1128e-12 20256300.0 73452.0 61328.0 51206.0 48372.0 57711.0 59276.0 49567.0 54476.0 57822.0 46532.3 True False 72404.56101055276 61185.99878398108 46996.04034087613 51929.43824426163 54316.55244419146 56740.90365910494 52133.33672680631 57007.15383441542 51309.477467346565 54575.34605460768 1.3266899111936972 1.1211289200577643 0.8611221684944012 0.9515182586712584 0.9952580491169534 1.0396801442602015 0.9552543500987073 1.0445587239588823 0.9401585363472856 1.0 15.735961752721238 -4.914399259016216 3.3613997628734826 0.9767834403661964 1.3306536789265615 0.8177973394648537 0.0516934978191912 0.10548026453334354 2.1331060548344505 0.013469828141580908 0.08028149760408498 1.217869462791833e-05 4.914399259016216 0.35387023856036515 NGS(ph)FIHSVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NGSFIHSVPR 10 0 B5A954;Q02763-3;Q02763-2;Q02763 B5A954 TEK Angiopoietin-1 receptor 1 NGS(0.982)FIHS(0.018)VPR 68.44 0.040982 4361400.0 12985.0 15132.0 19075.0 15185.0 21280.0 16814.0 15221.0 21754.0 16187.0 10676.0 True False 15183.104034559674 16634.20495609592 19529.820342340354 14334.233680434243 17110.33675975818 15932.244240644668 13779.15668950297 21182.98055026827 16423.70425220463 12611.474288830506 1.2039119048917826 1.3189738626219292 1.548575519012647 1.13660253766917 1.3567277201613248 1.263313382381887 1.09258888960402 1.6796593376104498 1.302282657528031 1.0 13.622449316980765 -5.790006637738085 24.996861652021334 1.2869089982650959 1.3533366147407335 0.03865938505735833 0.19084459275306112 1032.8711007965444 903777.0777918424 0.05373091521731596 0.07971094593025362 1.621785309872944e-06 5.790006637738085 0.06642761647563766 NGS(ph)PEIK ddPTM_PC-9_AZD4547_30min_R2 1 NGSPEIK 7 0 O96028;O96028-3;O96028-6;D6RIS1;D6R9V2;O96028-7;O96028-5 O96028;O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 NGS(1)PEIK 76.282 0.031484 11973000.0 197680.0 150580.0 107680.0 103990.0 119450.0 149350.0 166560.0 116990.0 167480.0 146850.0 True False 260538.1280005691 199252.04024760783 106252.09284313793 80016.71212948435 102866.42935708525 140011.12089030727 181383.51733052538 98911.88366275546 176332.65088280322 141708.82619766096 1.8385455231783545 1.4060665492330264 0.7497916375013466 0.5646558106258952 0.7258999465114697 0.9880197631092811 1.2799733241564264 0.6979938110897153 1.2443307563415111 1.0 17.112570092361338 -5.017556689833908 3.205257621815187 0.8950599707745854 1.8133552887437423 0.6446881317314237 0.22304977038919988 0.16001457675999534 3.2178675971986848 0.061240756997215255 0.27577737235332817 9.60380448703462e-06 5.017556689833908 0.9182953179691569 NGS(ph)PEIK ddPTM_PC-9_Lapatinib_30min_R1 1 NGSPEIK 7 0 O96028;O96028-3;O96028-6;D6RIS1;D6R9V2;O96028-7;O96028-5 O96028;O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 NGS(1)PEIK 77.533 0.029654000000000003 12565000.0 75437.0 169600.0 104720.0 113360.0 152070.0 114980.0 172370.0 158680.0 108100.0 133470.0 True False 74361.25454654862 169207.30162019318 96110.32583088972 121696.87255787427 143125.5415811231 110062.57343147113 181294.47518711258 166052.85208982052 95924.63965653499 156540.11166240438 0.4750300338798574 1.0809197708067755 0.6139661254245301 0.7774165436928184 0.9143058610421128 0.703095023139072 1.1581343162581463 1.0607687085846176 0.6127799363233292 1.0 17.2561728535223 -7.234307280005377 24.987696080854743 0.9629848698882695 0.7764003774874517 0.18425265183330009 0.20149250723012024 1314.594537980926 1210696.28265297 0.07407966005515472 0.057366522567662934 5.830324404866035e-08 7.234307280005377 -0.18658449240081776 NGS(ph)PNKQPSSEPEWTPEPR ddPTM_PC-9_AZD4547_30min_R2 2 NGSPNKQPSSEPEWTPEPR 19 1 Q5JSZ5;A0A494C0D3 Q5JSZ5 PRRC2B Protein PRRC2B 1 NGS(0.999)PNKQPSSEPEWTPEPR;NGS(0.971)PNKQPS(0.024)S(0.006)EPEWTPEPR 82.01 0.00093646 51693000.0 81771.0 75267.0 62714.0 54730.0 69051.0 75650.0 82665.0 77105.0 74681.0 93358.0 True False 107772.47705753976 99595.58582359341 61882.371383400336 42112.84407007093 59464.46055702043 70919.59354102271 90022.0248566756 65190.1939466342 78628.48519571676 90089.5648359635 1.196281470043435 1.1055174481632655 0.6868983271933519 0.46745529459211693 0.6600593605407492 0.7872120780043086 0.9992503018589237 0.7236153717173963 0.8727812742672777 1.0 16.459072386461997 -5.18549909684755 5.046658404855741 0.7584635857542291 1.1679808174093418 0.49208914164954076 0.1527578145997763 0.18287457609643848 8.431460873540482 0.041956790148356876 0.11739765804798315 6.523803976775285e-06 5.18549909684755 0.40951723165511267 NGS(ph)PNKQPSSEPEWTPEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NGSPNKQPSSEPEWTPEPR 19 1 Q5JSZ5;A0A494C0D3 Q5JSZ5 PRRC2B Protein PRRC2B 1 NGS(0.52)PNKQPS(0.129)S(0.339)EPEWT(0.012)PEPR 61.957 0.007698899999999999 18610000.0 25477.0 34632.0 16873.0 24654.0 25670.0 32041.0 34565.0 31371.0 29351.0 21406.0 True False 29789.752906313177 38070.03608508551 17275.31631120884 23272.716309346426 20640.147773636865 30360.71355504316 31290.752971070902 30547.544490322038 29780.20284836336 25286.738350197233 1.1780781093138024 1.5055336737325227 0.6831769314002529 0.9203526365101532 0.8162439729391148 1.2006575594913114 1.2374372897652433 1.2080460543098779 1.1777004387017387 1.0 14.626093340257206 NGS(ph)PNKQPSSEPEWTPEPR ddPTM_PC-9_Lapatinib_30min_R1 1 NGSPNKQPSSEPEWTPEPR 19 1 Q5JSZ5;A0A494C0D3 Q5JSZ5 PRRC2B Protein PRRC2B 1 NGS(0.79)PNKQPS(0.105)S(0.105)EPEWT(0.001)PEPR 72.676 0.0025632 33046000.0 20063.0 29481.0 16971.0 18340.0 18653.0 18626.0 16135.0 19461.0 19746.0 16119.0 True False 19776.897940896397 29412.73855580724 15575.709889954473 19688.784780446516 17555.86721320898 17829.409399326687 16970.391350838665 20365.22910587339 17521.99754540185 18905.147672782587 1.046111793634326 1.5558058082853405 0.8238872374627654 1.041450991085995 0.928628938375544 0.9430981290347379 0.8976598143832879 1.0772319507026573 0.9268373804150689 1.0 14.206491498166267 -5.274269196901756 24.999790383026742 0.9573018965798603 1.3009588256809095 0.5205490066797971 0.1328495811318656 473.10138505623104 921871.328469128 0.03163512933969995 0.06651093354379072 5.317785348153565e-06 5.274269196901756 0.34365692910104917 NGS(ph)PPPGAPSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NGSPPPGAPSSR 12 0 Q9Y3Q8 Q9Y3Q8 TSC22D4 TSC22 domain family protein 4 1 NGS(0.939)PPPGAPS(0.045)S(0.015)R 79.88600000000001 0.014894999999999999 4762700.0 11339.0 13150.0 12445.0 14777.0 15011.0 12860.0 14496.0 10249.0 10957.0 10969.0 True False 13258.468744541555 14455.4450946776 12741.735997925332 13949.092597680388 12069.702307365122 12185.598961263846 13122.833938048412 9979.974609713126 11117.225396392549 12957.592869443772 1.0232200438869552 1.1155964877370101 0.9833412830844943 1.0765188209126977 0.931477198656824 0.9404215029783487 1.0127524510354318 0.7702028231838971 0.8579699569515628 1.0 13.661510113368982 -6.605861132354005 0.8779162291221555 0.8836027080602884 1.0615087357044244 0.4125145779805617 0.07395521753306449 0.5378127406396526 0.9107404827839398 0.04316477580656518 0.04761095792947379 2.478214351324929e-07 6.605861132354005 0.177906027644136 NGS(ph)PPPGAPSSR ddPTM_PC-9_Lapatinib_30min_R1 2 NGSPPPGAPSSR 12 0 Q9Y3Q8 Q9Y3Q8 TSC22D4 TSC22 domain family protein 4 1 NGS(1)PPPGAPSSR;NGS(0.995)PPPGAPS(0.004)S(0.001)R 138.31 6.9019e-05 63488000.0 234041.0 170152.0 135983.0 161850.0 170180.0 149836.0 146832.0 137125.0 135134.0 120787.0 True False 230703.53242213663 169758.0234981079 124803.00264955992 173752.98891577247 160170.34698675296 143427.86356477573 154434.2425055061 143496.3280994241 119913.78589589456 141664.87201143918 1.6285161532741 1.198307110914555 0.8809735319528069 1.2265072240473436 1.1306285370011806 1.0124448039115455 1.090137874779824 1.0129280891019832 0.8464609764812532 1.0 17.11212253856649 -4.8140241755885125 3.1994919459681648 1.0378061606893747 1.6922106093684843 0.7457719107558864 0.10617941592826714 0.15586704374831611 2.5256342931224447 0.027320204669688576 0.24687234046053363 1.534531558651286e-05 4.8140241755885125 0.6544044486791096 NGS(ph)SANIPPLK ddPTM_PC-9_AZD4547_30min_R2 1 NGSSANIPPLK 11 0 K7EIG1;I3L2B0;A0A494C0R8;O75153 K7EIG1 CLUH Clustered mitochondria protein homolog 1 NGS(0.998)S(0.002)ANIPPLK 69.21600000000001 0.035269999999999996 5816800.0 20139.0 18763.0 36144.0 56396.0 52981.0 39573.0 38645.0 57739.0 44713.0 54585.0 True False 26542.783082777463 24827.772819536924 35664.70694392993 43394.77350951431 45625.50266862902 37098.494054182316 42084.33013471513 48816.76426022587 47076.43789660131 52673.99576438094 0.5039067702687205 0.4713478151647248 0.6770837569161028 0.8238367505595351 0.8661864741136986 0.7043037748670086 0.7989583764057876 0.9267716176040817 0.8937320439326762 1.0 15.68480328371195 -4.508112776157353 0.36948394143894775 0.9321160680139107 1.1465061867706519e-21 0.8118027055719108 0.07241097828453583 3.5219226779521464 0.3282687609867844 0.07068406727179906 1.523209608405779 3.103753511007639e-05 4.508112776157353 -0.9321160680139107 NGS(ph)SANIPPLK ddPTM_PC-9_Lapatinib_30min_R1 1 NGSSANIPPLK 11 0 K7EIG1;I3L2B0;A0A494C0R8;O75153 K7EIG1 CLUH Clustered mitochondria protein homolog 1 NGS(0.997)S(0.003)ANIPPLK 71.085 0.030608999999999997 4266200.0 12829.0 29945.0 45260.0 41334.0 38790.0 29319.0 25765.0 21808.0 34328.0 21037.0 True False 12646.056107449533 29875.664192315333 41538.89750865234 44373.84024618188 36508.44846407423 28065.094715927153 27098.985630886786 22821.279294018146 30461.619150134433 24673.217419959496 0.5125418340138913 1.2108540075583047 1.683562253014043 1.7984618499849754 1.479679275007749 1.1374720304302017 1.098315844652062 0.9249413607305541 1.2346026313330496 1.0 14.590658236783 -6.898909692574041 5.208363594782885 1.0659896098580923 1.3737834236975905 0.1281083158042119 0.3332044713094769 0.4407378855189394 18.864090441245494 0.12970260081670237 0.11409071017545087 1.2620899469626526e-07 6.898909692574041 0.3077938138394982 NGSLDS(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NGSLDSPGK 9 0 Q9Y266;A0A0A0MSS4;A0A0A0MSU9 Q9Y266 NUDC Nuclear migration protein nudC 1 NGSLDS(1)PGK 79.23 0.020447999999999997 4178100.0 37224.0 63322.0 40923.0 38975.0 48654.0 36307.0 51121.0 34798.0 28159.0 35761.0 True False 43525.28799248741 69608.18967948109 41898.759521341766 36791.35710865486 39120.5979656614 34402.99700517934 46278.44879601083 33884.58937152868 28570.77210340582 42244.18621607976 1.0303261085408246 1.6477578553279253 0.9918230950651734 0.8709211942317084 0.926058742510954 0.8143841812742564 1.0954986458798317 0.8021124894727147 0.6763243575640401 1.0 15.366465186166451 -5.453920995533249 7.376333121945271 0.8864998251143982 1.3383653622078022 0.5134477247803942 0.1748162303890878 0.19743810376911358 18.527956890030758 0.043289438042324366 0.09024736765846125 3.5162440029009352e-06 5.453920995533249 0.45186553709340405 NGSLDS(ph)PGK ddPTM_PC-9_Lapatinib_30min_R1 1 NGSLDSPGK 9 0 Q9Y266;A0A0A0MSS4;A0A0A0MSU9 Q9Y266 NUDC Nuclear migration protein nudC 1 NGS(0.003)LDS(0.997)PGK 80.834 0.018111000000000002 7313300.0 43009.0 45084.0 41680.0 39032.0 55746.0 44237.0 48129.0 47439.0 44641.0 39008.0 True False 42395.68377311538 44979.6107679527 38253.231289452735 41902.54348693499 52467.12988085282 42345.08663148362 50620.88412299438 49643.1891245839 39613.060489429954 45750.48082510722 0.9266718733554649 0.9831505583492911 0.8361274154841211 0.9158929639913089 1.14681045826429 0.9255659365277147 1.1064557838529723 1.0850856259709607 0.865850145725482 1.0 15.481499285358206 -6.074787276472867 24.996918926418275 1.0258690427790544 0.9144168826974469 0.2723870040473221 0.08483358072115543 166.61831502491344 55689.656778497825 0.024314212290200577 0.03138952585484567 8.418073697333474e-07 6.074787276472867 -0.11145216008160752 NGSMGS(ph)PVNQQPK ddPTM_PC-9_AZD4547_30min_R2 1 NGSMGSPVNQQPK 13 0 A0A0A0MRW1;A0A0A0MRV9;Q5T586;A0A0A0MRW2;Q5T593;A0A0A0MRW0;A0A0A0MRW3;Q8IW50-3;Q8IW50-7;Q8IW50-2;Q8IW50-5;Q8IW50-6;Q8IW50-4;Q8IW50 A0A0A0MRW1 FAM219A Protein FAM219A 1 NGS(0.09)MGS(0.91)PVNQQPK 98.25299999999999 0.0096549 0.0 4626.5 5505.6 6049.5 7902.1 8623.7 6257.0 7884.4 9139.2 7089.7 6011.9 True False 6097.630762821883 7285.1775321239875 5969.279677326918 6080.392931227979 7426.448110897412 5865.748800874807 8586.096325893335 7726.946637923348 7464.447068090584 5801.425210879944 1.0510573766229785 1.2557565197016463 1.028933315581175 1.0480860668211083 1.2801075323646187 1.0110875496376703 1.4799977615484972 1.3319048952716477 1.2866574672188866 1.0 12.502191649055051 -7.2476308928942474 24.99149107213977 1.3022987859698625 1.1199076641966215 0.23147439448038232 0.14079007473799407 1001.4543522079013 1812499.1808404534 0.05135537790081025 0.03956174169519188 5.6541731913416773e-08 7.2476308928942474 -0.18239112177324102 NGSMGS(ph)PVNQQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NGSMGSPVNQQPK 13 0 A0A0A0MRW1;A0A0A0MRV9;Q5T586;A0A0A0MRW2;Q5T593;A0A0A0MRW0;A0A0A0MRW3;Q8IW50-3;Q8IW50-7;Q8IW50-2;Q8IW50-5;Q8IW50-6;Q8IW50-4;Q8IW50 A0A0A0MRW1 FAM219A Protein FAM219A 1 NGS(0.001)MGS(0.999)PVNQQPK 98.59200000000001 0.0093043 0.0 7457.8 8366.0 7800.2 6762.5 10676.0 10754.0 8982.3 10444.0 9415.8 7164.8 True False 8720.258241735783 9196.521191032145 7986.186350423236 6383.619049320808 8584.114438307253 10190.041308664964 8131.431517779548 10169.85606633271 9553.488262056484 8463.721523474404 1.0303101558280086 1.0865812592634692 0.9435785816290495 0.7542331150210502 1.0142245836537669 1.2039669878554673 0.9607394921048337 1.2015820745196173 1.1287573953797485 1.0 13.047076444804032 -6.529381557341738 24.94149889048238 1.1036473027993081 0.952670430462606 0.29119790922825883 0.1071780052557466 209.9475093309898 805245.4078678936 0.03657952042605104 0.036667808111462995 2.9554147920078644e-07 6.529381557341738 -0.1509768723367021 NGSTAVAESVAS(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 3 NGSTAVAESVASPQK 15 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 NGSTAVAESVAS(1)PQK;NGSTAVAESVAS(1)PQK;NGSTAVAES(0.003)VAS(0.997)PQK 149.52 5.4494e-05 83807000.0 60427.3 54784.8 54945.6 77945.0 70419.5 72633.3 70153.4 66027.0 58399.5 68177.0 True False 79641.92443407909 72492.91522484491 54216.98544318274 59975.98448824553 60642.96795404997 68091.5282689117 76396.91669485635 55824.04429951905 61486.378345057805 65790.14398146365 1.2105449177390184 1.1018810848821028 0.8240897824825912 0.9116256761064961 0.9217637214950631 1.0349806847678653 1.1612213026373852 0.8485168282235019 0.9345834288245602 1.0 16.00558384961782 -5.033669007362574 5.877382399587184 0.9565339761495443 1.1876536485820264 0.4570529684693545 0.09137191171845127 0.14901860465850722 15.824113016693365 0.024843106592660917 0.07488216598928749 9.254031908404728e-06 5.033669007362574 0.2311196724324821 NGSTAVAESVAS(ph)PQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 NGSTAVAESVASPQK 15 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 NGSTAVAESVAS(1)PQK;NGST(0.001)AVAESVAS(0.999)PQK;NGSTAVAESVAS(1)PQK;NGS(0.006)T(0.001)AVAESVAS(0.992)PQK;NGSTAVAES(0.001)VAS(0.999)PQK 178.22 5.315199999999999e-21 54192800.0 153658.0 160115.0 137842.0 179125.0 178213.0 164892.0 187583.0 158949.0 145594.0 141878.0 True False 179669.26451616283 176010.1590368293 141128.67604869575 169089.20698108574 143293.44196272496 156244.77324422382 169813.7802566867 154776.75717038682 147723.03681321334 167599.35829436965 1.0720164226440159 1.0501839674570055 0.8420597637421673 1.008889346008708 0.8549760775995691 0.9322516197812478 1.0132125921295454 0.9234925404579333 0.8814057423403391 1.0 17.354657099683486 -5.120420379569341 7.342583876695647 0.9323527870842333 1.066435428726007 0.44220107125626895 0.05817648486294502 0.20936334265651801 11.508590795730765 0.014177529850524976 0.038202928929148464 7.578436577431467e-06 5.120420379569341 0.13408264164177364 NGSTAVAESVAS(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 2 NGSTAVAESVASPQK 15 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 NGSTAVAESVAS(1)PQK;NGSTAVAESVAS(1)PQK 164.53 4.764100000000001e-05 95568000.0 96932.0 84318.0 73608.0 81995.0 82826.0 76118.0 63822.0 73734.0 66851.0 56631.0 True False 95549.73190484842 84122.76685148268 67556.23437509674 88025.18582730168 77954.33752218133 72862.61057972445 67126.3908765557 77159.95081920075 59321.53640776152 66419.59289393567 1.438577500127563 1.2665354180327018 1.0171130449862311 1.3252894513802218 1.1736647896452077 1.0970047753240153 1.0106414079313721 1.1617046635985284 0.8931330925573586 1.0 16.019321259696603 -1.5228787452804973 0.23325184806463445 0.9785868031505973 3.2918245806508475 0.5728176180272875 0.10443088744338332 39.72546626259133 0.5236179790033588 0.1508225691609694 35.242870548549874 0.02999999999998897 1.5228787452804973 2.31323777750025 NGSVVSLQS(ph)PGSR ddPTM_PC-9_AZD4547_30min_R2 1 NGSVVSLQSPGSR 13 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 NGSVVS(0.001)LQS(0.994)PGS(0.005)R 99.796 0.0024164 5345700.0 12291.0 13739.0 15536.0 22360.0 22266.0 23079.0 14789.0 15869.0 18718.0 18881.0 True False 16199.28233131824 18179.86306921161 15329.982488957923 17205.247458556285 19174.750239136552 21635.866481602963 16105.192349910765 13416.810683342703 19707.395266445634 18219.98193692913 0.8890943134518021 0.9977980841113676 0.8413829685465485 0.9443065046998684 1.0524022639271806 1.1874801279440546 0.8839302039739124 0.7363789234142363 1.0816363778331604 1.0 14.153233908419617 -1.8156971906205048 19.73633554234288 0.9579696772344966 0.09643526042396056 0.0 0.12383300356503965 0.0 0.0 0.029373509266048394 0.0 0.015286315164608683 1.8156971906205048 -0.861534416810536 NGSVVSLQS(ph)PGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NGSVVSLQSPGSR 13 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 NGSVVS(0.001)LQS(0.951)PGS(0.049)R 95.751 0.0034366999999999996 2289400.0 10832.0 10786.0 12429.0 23140.0 18326.0 17746.0 12505.0 13360.0 13098.0 13579.0 True False 12665.643658248007 11856.762797809322 12725.354497244993 21843.54082089222 14735.151854291742 16815.368519952444 11320.435871640137 13009.314156090102 13289.533471018487 16040.765208695144 0.7895909885509951 0.739164412891112 0.7933134318521798 1.3617517952978697 0.9186065416819595 1.0482896732904872 0.7057291671786157 0.8110158079639619 0.8284850066762832 1.0 13.96945534531096 -10.599032426724271 14.534716933620327 1.0000001212569998 0.8931091560678405 0.031828242556363295 0.18296395086362804 0.0 0.0 0.18792804914189767 0.045579246860488865 2.5174889516938113e-11 10.599032426724271 -0.1068909651891593 NGSVVSLQS(ph)PGSR ddPTM_PC-9_Lapatinib_30min_R1 2 NGSVVSLQSPGSR 13 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 NGSVVSLQS(0.992)PGS(0.008)R;NGSVVSLQS(0.978)PGS(0.022)R 123.76 0.00016202 7224000.0 49379.0 35548.0 30034.0 34683.0 42274.0 34813.0 32652.0 33517.0 39199.0 32257.0 True False 48674.84640500044 35465.69079006261 27564.720454592687 37233.70351909631 39787.52643388177 33324.12914306666 34342.56079253698 35074.322179824194 34783.99583623047 37832.57947024926 1.286585453240832 0.937437819114398 0.7285974374617782 0.9841703642855256 1.051673636611795 0.8808315375183987 0.9077509721361516 0.9270930682219515 0.9194190912513346 1.0 15.207341523953378 -4.76373371152728 6.306084786034089 0.9208242126824581 1.2975736945256064 0.6382482462162105 0.08135801904989054 0.07867980297463459 13.684267588463586 0.020807962635747274 0.127958102735134 1.722924665657627e-05 4.76373371152728 0.3767494818431484 NGSY(ph)RPSY(ph)EEMLRFY(ph)SYYK ddPTM_PC-9_AZD4547_30min_R2 1 NGSYRPSYEEMLRFYSYYK 19 2 K7EM05;Q8NC06;Q8NC06-2;Q8NC06-3 K7EM05 ACBD4 Acyl-CoA-binding domain-containing protein 4 3 NGS(0.133)Y(0.775)RPS(0.21)Y(0.567)EEMLRFY(0.734)S(0.198)Y(0.191)Y(0.191)K 40.515 0.036654 11415000.0 20330.0 16444.0 24114.0 32105.0 29554.0 29350.0 26537.0 33341.0 25013.0 23382.0 True False 26794.517109730677 21759.20142005357 23794.2326041923 24703.688267305428 25450.937239173698 27514.73986026462 28898.741591019138 28188.914549960875 26335.136114948415 22563.403296926892 1.1875210825744562 0.9643581304517633 1.054549807538699 1.0948564780859118 1.1279742202117216 1.2194410345894982 1.2807793758202741 1.249320157026142 1.1671615211759845 1.0 14.461697069151958 -6.449816718777206 2.265491555861305 1.2043640212335438 1.063212415834415 0.22877435001119617 0.08813457974515229 0.35046412733248317 3.560756737302646 0.03004211175361945 0.03389623681013241 3.5496315939786913e-07 6.449816718777206 -0.14115160539912885 NGTGQS(ph)SDSEDLPVLDNSSK ddPTM_PC-9_AZD4547_30min_R2 1 NGTGQSSDSEDLPVLDNSSK 20 0 P29374 P29374 ARID4A AT-rich interactive domain-containing protein 4A 1 NGT(0.032)GQS(0.484)S(0.484)DSEDLPVLDNSSK 131.18 2.0536e-06 0.0 3642.3 2960.9 3014.0 4182.7 4622.6 4523.7 3010.7 3677.7 3185.6 3386.8 True False 4800.475635453614 3917.9530214446954 2974.0323906873837 3218.443137070815 3980.8317818841547 4240.832323880035 3278.646467501276 3109.3959701386016 3353.9843124687045 3268.229162861691 1.4688307937532368 1.1987999697102332 0.9099828202020247 0.984766666194459 1.2180393673491678 1.2975933181401282 1.0031874462041896 0.9514008397795418 1.0262390258863996 1.0 11.674293431099434 -4.863839539625666 3.3761539290957354 1.0577010163033487 1.488259129498412 0.5563482336935968 0.11434498970637953 0.2253517141553436 4.294741187701349 0.0323205403524469 0.22241304074730278 1.3682342587454464e-05 4.863839539625666 0.4305581131950633 NGTKS(ph)PEAATPVGK ddPTM_PC-9_AZD4547_30min_R2 1 NGTKSPEAATPVGK 14 1 A0A2R8YH03;Q5VWN6 A0A2R8YH03 FAM208B Protein FAM208B 1 NGT(0.203)KS(0.796)PEAATPVGK 98.507 0.011759 3881700.0 16678.0 16251.0 18139.0 23250.0 16692.0 17940.0 16558.0 19660.0 17409.0 19895.0 True False 21981.2570760496 21503.817944374277 17898.465008187944 17890.07170891921 14374.603924892986 16818.208963991394 18031.629922903674 16621.99874185629 18329.20419882209 19198.4821055667 1.1449476555063702 1.120079068028984 0.9322854228667479 0.931848237300588 0.7487364806160897 0.8760176388692138 0.9392216438650276 0.8657975484966414 0.9547215294435929 1.0 14.228704630842865 -5.287646434962382 2.509338738084933 0.8914460495732057 1.149706521060803 0.6675060606246574 0.06401943263227265 0.1672167364681824 2.0144195066662096 0.017728456600907022 0.05606294174323355 5.156482700089071e-06 5.287646434962382 0.25826047148759734 NGTKS(ph)PEAATPVGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NGTKSPEAATPVGK 14 1 A0A2R8YH03;Q5VWN6 A0A2R8YH03 FAM208B Protein FAM208B 1 NGT(0.005)KS(0.995)PEAATPVGK 149.0 0.0010612 3591400.0 16639.0 13105.0 8750.0 17906.0 17953.0 14647.0 17742.0 11445.0 16913.0 12391.0 True False 19455.65406477 14405.977792072244 8958.633184559794 16902.78487203526 14435.238526688836 13878.885535430149 16061.349319043533 11144.58087697987 17160.320628747555 14637.390212897972 1.3291750634362631 0.9841903223552916 0.6120376005734787 1.1547676618705633 0.9861893627710351 0.9481803336226252 1.0972823082143985 0.7613775895077008 1.172362038529687 1.0 13.837370729445768 -4.767094605450671 6.011826628377222 0.9586727964412821 1.3415285720227408 0.3057293774713723 0.1628223373438441 0.1495913625592882 20.904755873614484 0.038843975252362016 0.2350019815144313 1.70964285088209e-05 4.767094605450671 0.38285577558145867 NGTKS(ph)PEAATPVGK ddPTM_PC-9_Lapatinib_30min_R1 1 NGTKSPEAATPVGK 14 1 A0A2R8YH03;Q5VWN6 A0A2R8YH03 FAM208B Protein FAM208B 1 NGT(0.002)KS(0.998)PEAATPVGK 147.7 7.9988e-08 0.0 33282.0 21665.0 19811.0 20595.0 20289.0 18657.0 18276.0 17593.0 20271.0 17050.0 True False 32807.39257682869 21614.83602359363 18182.216052671494 22109.625002905996 19095.640909708745 17859.083601591206 19222.24185484521 18410.435006404114 17987.86651690676 19997.069782303053 1.6406099960636473 1.0809001648192609 0.9092440167790151 1.1056432389145587 0.9549219519455769 0.8930850267570745 0.9612529267591221 0.9206566365386656 0.8995251160660352 1.0 14.28750099353689 -4.757121583001544 3.017012164674073 0.9565192778438629 1.7752953169523207 0.9222785156029631 0.059420879812483944 0.10558718875095047 1.327985473400342 0.01563536708324964 0.21741068142218892 1.7493568784985186e-05 4.757121583001544 0.8187760391084578 NGTSGS(ph)DSPGQAVEAEEIVK ddPTM_PC-9_AZD4547_30min_R2 1 NGTSGSDSPGQAVEAEEIVK 20 0 Q05D32 Q05D32 CTDSPL2 CTD small phosphatase-like protein 2 1 NGTS(0.001)GS(0.499)DS(0.499)PGQAVEAEEIVK 111.88 4.8889e-05 2842400.0 13314.0 13839.0 12593.0 21305.0 16143.0 17714.0 16911.0 17282.0 13805.0 15610.0 True False 17547.575051596363 18312.186113605047 12426.00859187997 16393.46140896877 13901.82309846318 16606.340779718146 18416.046239052084 14611.464000852508 14534.704116533925 15063.498651314221 1.1649070018714023 1.215666196644655 0.8249085341668523 1.0882904289660833 0.9228814248441751 1.102422562255769 1.2225610175525436 0.9699913903851098 0.9648956363311945 1.0 13.878769269127037 NGTSGS(ph)DSPGQAVEAEEIVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NGTSGSDSPGQAVEAEEIVK 20 0 Q05D32 Q05D32 CTDSPL2 CTD small phosphatase-like protein 2 1 NGTSGS(0.956)DS(0.044)PGQAVEAEEIVK;NGT(0.012)S(0.033)GS(0.505)DS(0.451)PGQAVEAEEIVK 166.79 4.0254000000000004e-08 7154800.0 44124.0 42490.0 39712.0 41497.0 54080.0 44591.0 50278.0 43294.0 45252.0 33516.0 True False 51593.32171127537 46708.12639337272 40658.88468859868 39172.05762508922 43483.4122165283 42252.56946203083 45515.30385880231 42157.57837378478 45913.724891626836 39592.185487489995 1.303118811856885 1.1797309448383737 1.0269421651766542 0.989388616535616 1.0982826959695826 1.0671946734383086 1.1496032183720661 1.0647954351271005 1.1596663413828032 1.0 15.272928085839904 -4.95266238840596 3.12752210526128 1.0732232166827798 1.3039855617905414 0.6503817124838385 0.053990435681277586 0.1732046387928385 3.154042956957986 0.01428724408001527 0.08081224492772449 1.115161100015853e-05 4.95266238840596 0.2307623451077616 NGTSGSDS(ph)PGQAVEAEEIVK ddPTM_PC-9_AZD4547_30min_R2 2 NGTSGSDSPGQAVEAEEIVK 20 0 Q05D32 Q05D32 CTDSPL2 CTD small phosphatase-like protein 2 1 NGT(0.001)S(0.002)GS(0.294)DS(0.704)PGQAVEAEEIVK;NGTS(0.001)GS(0.169)DS(0.83)PGQAVEAEEIVK 135.31 8.6615e-05 6684100.0 24569.1 25140.7 22674.2 32435.0 33814.2 32775.5 24937.7 32264.0 24612.8 28443.3 True False 32381.56273097313 33266.93962181588 22373.525292940914 24957.611865754603 29119.682005578507 30726.042803751367 27157.106989273794 27278.340152962945 25913.782359972927 27447.508724466716 1.1797632730910912 1.212020367887222 0.8151386531119725 0.909285141915535 1.0609225885634281 1.1194474191518213 0.9894197415835392 0.993836651143753 0.9441214727394686 1.0 14.744387588380501 -5.229374658546667 24.920119015365866 0.9846223666982515 1.1958919336308762 0.5518610541885287 0.07804161310270183 522.4893942896578 406067.62954658986 0.021689664494330362 0.05737520697013483 5.8969214318175085e-06 5.229374658546667 0.21126956693262466 NGTSGSDS(ph)PGQAVEAEEIVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NGTSGSDSPGQAVEAEEIVK 20 0 Q05D32 Q05D32 CTDSPL2 CTD small phosphatase-like protein 2 1 NGTSGS(0.001)DS(0.999)PGQAVEAEEIVK;NGTSGSDS(1)PGQAVEAEEIVK 119.94 1.2362000000000001e-05 6121000.0 38210.8 39058.2 36396.8 45077.0 41879.7 43436.6 50555.0 37716.0 38087.7 32573.9 True False 44679.13374229905 42935.639969348755 37264.63774763269 42551.48183160578 33673.67342094193 41158.70823023589 45766.06441349595 36725.994963405254 38644.660557650815 38479.290215149456 1.1611215667566728 1.1158116412564392 0.9684336051750104 1.105828137517284 0.8751116050390261 1.0696327297126582 1.1893687268555089 0.9544353536164261 1.004297645345762 1.0 15.231794567105215 -5.076262408775719 5.114081430394938 1.0250824992744803 1.151827287994106 0.25307394910149217 0.0821046561562681 0.2782602333102601 12.877079895297559 0.021204934854491448 0.062195469501390266 8.389529224401334e-06 5.076262408775719 0.1267447887196258 NGTSGSDS(ph)PGQAVEAEEIVK ddPTM_PC-9_Lapatinib_30min_R1 3 NGTSGSDSPGQAVEAEEIVK 20 0 Q05D32 Q05D32 CTDSPL2 CTD small phosphatase-like protein 2 1 NGTS(0.001)GS(0.317)DS(0.681)PGQAVEAEEIVK;NGT(0.001)S(0.104)GS(0.257)DS(0.638)PGQAVEAEEIVK;NGT(0.002)S(0.011)GS(0.332)DS(0.655)PGQAVEAEEIVK 157.59 1.4589e-05 7983000.0 54207.0 44519.0 39327.9 34209.0 41973.8 40158.3 39002.4 36853.2 47797.0 32741.7 True False 53433.99823965366 44415.91899073921 36094.51187208416 36724.84397787865 39504.98360766586 38440.82312256955 41021.75343179113 38565.53421122106 42413.5985352766 38401.05921942709 1.3914719886846614 1.1566326526813406 0.9399353196440986 0.9563497654590621 1.0287472379845268 1.0010354897482188 1.0682453626445343 1.0042830847673796 1.1044903291058068 1.0 15.228858485015131 -4.87856574984925 2.910577449735201 1.0137199255175677 1.4179950150492233 0.8610429599088668 0.04675451304493203 0.11329527581903405 1.5642235452872275 0.012483631236087991 0.09769456898513476 1.3226174556810085e-05 4.87856574984925 0.4042750895316556 NGTSSTCQDS(ph)PEKTTLAAK ddPTM_PC-9_Lapatinib_30min_R1 2 NGTSSTCQDSPEKTTLAAK 19 1 Q9BX63;Q9BX63-2 Q9BX63 BRIP1 Fanconi anemia group J protein 1 NGT(0.042)S(0.195)S(0.147)T(0.147)CQDS(0.47)PEKTTLAAK;NGTS(0.001)S(0.002)T(0.009)CQDS(0.953)PEKT(0.026)T(0.008)LAAK 83.229 0.00075678 12691200.0 72678.0 46255.0 38458.0 48152.0 42751.0 42258.0 35621.0 38809.0 37808.0 34995.0 True False 71641.59839248718 46147.89938939872 35296.13169217304 51693.25871036315 40236.47023169987 40450.72384820932 37465.28108510843 40612.207819220006 33549.664904109864 41043.83912209359 1.7454896989381057 1.124356307218777 0.8599617493669933 1.2594645095599029 0.9803291088830157 0.985549225253517 0.9128113228799094 0.9894836518194703 0.8174104962332905 1.0 15.324878062330711 -4.774364655357842 3.36934987472421 0.9833394807071145 1.8522900328128398 0.8088316191776463 0.11183606832649431 0.1305137110512422 2.3370869107668857 0.02820306875108228 0.29921725855308756 1.681261796796968e-05 4.774364655357842 0.8689505521057252 NGVAAEVS(ph)PAKEENPR ddPTM_PC-9_AZD4547_30min_R2 3 NGVAAEVSPAKEENPR 16 1 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 NGVAAEVS(1)PAKEENPR;NGVAAEVS(1)PAKEENPR;NGVAAEVS(1)PAKEENPR 89.311 0.0081579 80019400.0 122643.0 111848.0 109722.0 135885.0 125607.0 133121.0 134386.0 122823.0 142001.0 118385.0 True False 161640.92286712714 148000.6786931494 108267.01458891889 104558.8126523221 108168.63618464129 124796.92282583594 146346.09365982175 103843.5275417606 149506.88295921276 114240.37718358963 1.4149193730983802 1.2955198708360827 0.9477123347984814 0.9152526911241827 0.9468511821421005 1.0924064319682825 1.281036506248896 0.9089914625796376 1.3087043884575784 1.0 16.80171312222175 -5.094939961935574 4.406168816539259 1.0489578869048188 1.391769792387401 0.4548017546327685 0.13611218931652322 0.1863433456156126 6.057913989908339 0.03543054979279008 0.10850320659852282 8.036372115266515e-06 5.094939961935574 0.3428119054825822 NGVAAEVS(ph)PAKEENPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NGVAAEVSPAKEENPR 16 1 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 NGVAAEVS(1)PAKEENPR;NGVAAEVS(1)PAKEENPR 96.805 0.01098 13194700.0 53482.0 57139.0 51383.0 70560.0 58428.0 52055.0 72105.0 66390.0 51065.0 49122.0 True False 62535.44628235045 62811.38230150444 52608.16559111262 66606.75195860634 46979.45282890746 49325.14416240978 65274.692405006936 64647.3328460195 51811.72901951126 58027.42975046197 1.077687682381841 1.0824429510597855 0.9066085783455504 1.1478494264701784 0.809607680900832 0.8500315174138329 1.124893738800955 1.1140823076952642 0.8928834043196403 1.0 15.824447407555251 -5.220439941479285 23.418561898269566 0.9851548010222728 1.0800655144881355 0.10987142109343162 0.11252071690190102 603.5531785408255 344740.0599063339 0.02953197566237747 0.07813109612612669 6.019495006528381e-06 5.220439941479285 0.09491071346586266 NGVAAEVS(ph)PAKEENPR ddPTM_PC-9_Lapatinib_30min_R1 2 NGVAAEVSPAKEENPR 16 1 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 NGVAAEVS(1)PAKEENPR;NGVAAEVS(1)PAKEENPR 107.41 0.00042959 91407000.0 199373.0 155466.0 148795.0 166062.0 197305.0 188559.0 186415.0 178989.0 171632.0 153696.0 True False 196529.90445946986 155106.02802880242 136561.64946530986 178274.75344659228 185699.90781655512 180494.77112249774 196066.65656439995 187305.4823714698 152300.99679491576 180262.14881295356 1.0902449890542263 0.8604470159165026 0.7575725151651838 0.9889749712879354 1.0301658392480608 1.0012904667512066 1.0876751323310014 1.039072726054235 0.8448861715997223 1.0 17.45973696797541 -5.971295593587918 24.999121077614642 1.0071114280251194 0.8943156094563349 0.1704129497760356 0.09626998908089454 325.63722904238887 283600.5257389909 0.02742770001492411 0.040681174338657214 1.0683274966203405e-06 5.971295593587918 -0.11279581856878451 NGVDPPPRARAAS(ph)VIPGS(ph)T(ph)S(ph)RLLPAR ddPTM_PC-9_AZD4547_30min_R2 1 NGVDPPPRARAASVIPGSTSRLLPAR 26 3 J3KPJ3;Q8N5S9;Q8N5S9-2 J3KPJ3 CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 4 NGVDPPPRARAAS(1)VIPGS(1)T(1)S(1)RLLPAR 49.497 0.033932 53284000.0 77193.0 119750.0 117180.0 118160.0 97612.0 118430.0 95290.0 121250.0 103070.0 102160.0 True False 101738.7682858554 158456.84566111752 115626.11663594816 90920.03755380199 84060.2587057666 111024.553378233 103770.6253988097 102513.59854781681 108518.06977842459 98583.40949508398 1.032006995973585 1.6073378520045933 1.1728760166457222 0.9222650953083121 0.8526815935490484 1.1261991642089577 1.052617534028222 1.0398666375291963 1.1007741600155958 1.0 16.589057256851852 -5.521257251449687 14.512783328723222 1.0172857592679974 1.3372856060263796 0.4061704455642967 0.14937743848020865 0.24961643739727601 2171.641739317009 0.038545333480925585 0.06960504710548572 3.011221818577876e-06 5.521257251449687 0.3199998467583822 NGVPS(ph)PIMATK ddPTM_PC-9_Lapatinib_30min_R1 1 NGVPSPIMATK 11 0 A0A1W2PP44;H3BSA7;A0A1W2PRM3;A0A286YFC2;A6NNM8-2;A6NNM8 A0A1W2PP44 TTLL13P Tubulin polyglutamylase TTLL13P 1 NGVPS(0.824)PIMAT(0.176)K 83.045 0.011685 7271400.0 25842.0 63834.0 92257.0 76950.0 72171.0 71467.0 59170.0 56024.0 79351.0 51514.0 True False 25473.488341157594 63686.196294949266 84671.98558231878 82609.15969767496 67926.04367364522 68410.52300771394 62233.5330789665 58627.0795656673 70413.65477692605 60418.12626190967 0.4216199660136968 1.0540908868784291 1.401433490593035 1.3672909904482675 1.124265975730348 1.132284750294268 1.0300473869246976 0.9703558053343417 1.1654392337770663 1.0 15.882693822228877 -4.774549946132389 4.284734535331747 1.1542944542898725 0.362069215248159 0.7207848919997422 0.1348349839036252 0.11862064689041184 4.476403700122141 0.03745010313610212 0.28838728635833233 1.6805446431884735e-05 4.774549946132389 -0.7922252390417135 down NHAAPFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NHAAPFSK 8 0 A0A087WYC1;P34932;A0A087WTS8;Q92598-2;Q92598-3;Q92598;A0A0A0MSM0;Q92598-4 A0A087WYC1;Q92598-2 HSPA4;HSPH1 Heat shock 70 kDa protein 4;Heat shock protein 105 kDa 0 65.22399999999999 0.043948 3911300.0 56958.0 52321.0 53418.0 80699.0 87818.0 78052.0 75456.0 78540.0 71570.0 60054.0 False True 66599.86442822091 57515.08310255717 54691.68770889312 76177.69665968804 70610.69330678768 73958.81571730682 68308.26142586781 76478.40822000866 72616.57585286257 70941.31481279747 0.9388022283484182 0.8107417131234467 0.7709426848545948 1.0738128671664533 0.9953395069307321 1.0425351702667485 0.9628840627795261 1.0780517449080649 1.0236147447292998 1.0 16.11433844870505 -5.764733076616969 24.99999697867158 1.02531354193383 0.8372201482450033 0.7321951833144987 0.05126636917893703 40.366015694533 306391.97558459104 0.014049893320305032 0.02185138943000999 1.7189645619007146e-06 5.764733076616969 -0.1880933936888266 NHAAPFSK ddPTM_PC-9_Lapatinib_30min_R1 1 NHAAPFSK 8 0 A0A087WYC1;P34932;A0A087WTS8;Q92598-2;Q92598-3;Q92598;A0A0A0MSM0;Q92598-4 A0A087WYC1;Q92598-2 HSPA4;HSPH1 Heat shock 70 kDa protein 4;Heat shock protein 105 kDa 0 76.679 0.020659999999999998 3190100.0 91465.0 81607.0 70923.0 73346.0 81501.0 84600.0 78702.0 69669.0 78169.0 71114.0 False True 90160.69232737338 81418.04400541921 65091.98471069709 78740.10951508352 76707.27141713108 80981.85521223223 82776.80446815644 72906.07607918879 69364.78406393784 83405.96014655114 1.0809862049301229 0.9761657783491853 0.7804236603274528 0.944058546616221 0.9196857308800245 0.9709360706350055 0.9924567060041126 0.8741111061018518 0.8316526054260176 1.0 16.34786286114069 -7.783420964841749 24.997557497521555 0.889661371205554 0.9455926223090674 0.06451296722118349 0.08114211494924316 673.0818710382626 765420.5461584914 0.04548291596563481 0.021876513380069875 1.6465655895945853e-08 7.783420964841749 0.05593125110351338 NHACEMCGK ddPTM_PC-9_Lapatinib_30min_R1 1 NHACEMCGK 9 0 I3L2Z5;A0A087WWR2;P56270-3;P56270;P56270-2;J3QSH4;Q14119 I3L2Z5 MAZ;VEZF1 Myc-associated zinc finger protein;Vascular endothelial zinc finger 1 0 64.654 0.033566000000000006 0.0 626.53 1181.1 992.77 406.58 673.81 476.95 1156.1 978.53 724.76 667.73 False True 617.5955673084693 1178.3652355165675 911.1482828030222 436.48124951112015 634.1778205614294 456.5519603247538 1215.9572011592559 1023.9960760993928 643.1298967388558 783.1462408057017 0.7886082255506791 1.5046554195347526 1.1634458997921409 0.5573432224638757 0.8097821166950716 0.5829715275847492 1.5526566275901137 1.3075413284827933 0.8212130292258097 1.0 9.613137924092035 -7.259045574932848 24.999501506092265 1.1959811750931157 0.9207111917725034 0.14529286377828932 0.31532439760053654 464.22631116962776 4848141.474918892 0.13340613399562662 0.09836810544559164 5.5074989758982914e-08 7.259045574932848 -0.27526998332061237 NHAGS(ph)PGCEESDAGK ddPTM_PC-9_AZD4547_30min_R2 2 NHAGSPGCEESDAGK 15 0 P42575 P42575 CASP2 Caspase-2;Caspase-2 subunit p18;Caspase-2 subunit p13;Caspase-2 subunit p12 1 NHAGS(1)PGCEESDAGK;NHAGS(1)PGCEESDAGK 96.391 0.0015038 12534400.0 101343.0 123525.0 106445.0 110605.0 102727.0 121851.0 108617.0 123605.0 125645.0 136715.0 True False 133567.96593465013 163452.0405869689 105033.46975007244 85106.72608021539 88465.12924709327 114231.63770743093 118283.7025809899 104504.68741033309 132286.33819064876 131928.64946280755 1.0124257807422241 1.2389427258788717 0.7961384443617971 0.6450966217478646 0.6705528299373122 0.8658592214243378 0.8965732845945313 0.792130351033377 1.0027112286019577 1.0 17.00939836692423 -5.272320001058187 24.63942092071719 0.8170499245371415 1.1256842530892828 0.4651507878927268 0.12425367596914992 429.41823153754086 972429.1374996195 0.033307216494762086 0.07048442547589553 5.341706215950692e-06 5.272320001058187 0.30863432855214123 NHAGS(ph)PGCEESDAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NHAGSPGCEESDAGK 15 0 P42575 P42575 CASP2 Caspase-2;Caspase-2 subunit p18;Caspase-2 subunit p13;Caspase-2 subunit p12 1 NHAGS(1)PGCEESDAGK 104.78 0.0011154000000000001 2297500.0 15547.0 20405.0 13972.0 14237.0 15186.0 13669.0 16124.0 13717.0 10714.0 12670.0 True False 18178.80003275312 22430.67354805295 14305.145469105066 13439.347046976769 12210.412313613142 12952.173577100744 14596.617992349107 13356.943284362858 10870.67198110338 14966.970704335177 1.2145944822012404 1.498678255684426 0.9557809493781922 0.8979336775934269 0.8158238934800882 0.8653837729066411 0.975255332605228 0.8924279701098116 0.7263107676127604 1.0 13.869494630866969 -5.366042723401867 5.134622305018916 0.8817104074264578 1.3535440583621938 0.7878063164452065 0.09703606384087467 0.08400639435720839 3.301288859111318 0.02462636515353021 0.053087342917388286 4.304842598345786e-06 5.366042723401867 0.47183365093573604 NHAGS(ph)PGCEESDAGK ddPTM_PC-9_Lapatinib_30min_R1 2 NHAGSPGCEESDAGK 15 0 P42575 P42575 CASP2 Caspase-2;Caspase-2 subunit p18;Caspase-2 subunit p13;Caspase-2 subunit p12 1 NHAGS(1)PGCEESDAGK;NHAGS(1)PGCEESDAGK 96.56200000000001 0.001485 14514900.0 57640.0 109722.0 82353.0 109882.0 115807.0 115161.0 106881.0 127299.0 94275.0 131317.0 True False 56818.04303011858 109467.94545029955 75582.25423177308 117963.08883560644 108995.45994532213 110235.83248340269 112414.77520725051 133213.7762678476 83656.75674023903 154014.968481096 0.36891247383589537 0.7107617300440235 0.4907461591374487 0.7659196375453947 0.7076939405321527 0.7157475248708256 0.7298951284793364 0.8649404507990951 0.5431728978375707 1.0 17.23271104551298 -5.018488747005389 0.10068728514362567 1.1483518600936269 4.699047622839634e-25 0.47655469157790664 0.12527620507567533 47.60775005129776 0.8449455665749949 2.340687060953374 8.577928171585336 9.583215470328598e-06 5.018488747005389 -1.1483518600936269 NHAGS(ph)PGCEESDAGKEK ddPTM_PC-9_AZD4547_30min_R2 3 NHAGSPGCEESDAGKEK 17 1 P42575 P42575 CASP2 Caspase-2;Caspase-2 subunit p18;Caspase-2 subunit p13;Caspase-2 subunit p12 1 NHAGS(0.984)PGCEES(0.016)DAGKEK;NHAGS(1)PGCEESDAGKEK;NHAGS(0.999)PGCEES(0.001)DAGKEK 91.616 0.0010313 23944900.0 90984.0 70497.0 77843.0 88409.0 77846.0 100302.0 85084.0 87269.0 84645.0 109994.0 True False 119915.01941523519 93283.77660602739 76810.75095828738 68027.67095543387 67038.42661977107 94030.10008396141 92656.31117045134 73783.58129211879 89119.16189380769 106143.14353956809 1.1297481440290416 0.8788488214620572 0.7236524979086739 0.640904995715286 0.6315850876866149 0.8858801138568958 0.872937319177012 0.695132806808324 0.8396129879136829 1.0 16.695651655845502 -4.821881721828111 2.8760379317040896 0.7719737846587682 1.1753013812704993 0.45647773148781323 0.11200653087435292 0.3224419329533117 3.9980719424692635 0.02922762017118809 0.294857654372639 1.5070174398041572e-05 4.821881721828111 0.4033275966117311 NHAGS(ph)PGCEESDAGKEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NHAGSPGCEESDAGKEK 17 1 P42575 P42575 CASP2 Caspase-2;Caspase-2 subunit p18;Caspase-2 subunit p13;Caspase-2 subunit p12 1 NHAGS(1)PGCEESDAGKEK;NHAGS(0.987)PGCEES(0.013)DAGKEK;NHAGS(1)PGCEESDAGKEK 99.74700000000001 0.00057913 17158500.0 52177.0 39591.8 36636.2 53172.0 57016.0 53275.0 56212.0 55590.0 38369.9 46667.9 True False 61009.535557275354 43522.21225090925 37509.7459515622 50192.945225949894 45844.124092780636 50481.16521472254 50887.19242036269 54130.82140247366 38930.987198780895 55128.42084710688 1.1066802679960515 0.7894695981155296 0.6804066827089371 0.9104731181245872 0.8315878341577151 0.9157012742071275 0.9230663900475798 0.9819040808841603 0.7061872370106894 1.0 15.750508655589803 -6.768159221827178 24.686993395093403 0.9053467189183236 0.8520112167865393 0.02272969813432324 0.12528239476596106 554.2453128078567 2036140.6876141035 0.043486649816478526 0.0392320782469415 1.705457016641505e-07 6.768159221827178 -0.053335502131784285 NHAGS(ph)PGCEESDAGKEK ddPTM_PC-9_Lapatinib_30min_R1 3 NHAGSPGCEESDAGKEK 17 1 P42575 P42575 CASP2 Caspase-2;Caspase-2 subunit p18;Caspase-2 subunit p13;Caspase-2 subunit p12 1 NHAGS(1)PGCEESDAGKEK;NHAGS(1)PGCEESDAGKEK;NHAGS(1)PGCEESDAGKEK 80.733 0.0026205 18720800.0 38304.1 71737.0 57885.0 81071.0 78161.0 81489.0 62293.0 71457.0 72842.0 93775.0 True False 37757.87650988835 71570.89738400826 53125.91874256168 87033.23178492788 73563.72365043842 78003.90543013703 65518.226738010126 74777.15308660378 64637.766899734765 109983.88380266659 0.3433037205490365 0.650739862145812 0.48303366734966696 0.7913271360837116 0.6688591192362935 0.709230322963425 0.5957075207087896 0.6798919123529877 0.5877021674894481 1.0 16.746932612174184 -14.522878745280336 0.12370609420581623 2.1454469020148372 0.459827840623429 0.5316368763486363 0.1136942873956553 127.87018452206367 1.011665097172009 37.19277516668847 1.002696150331308 3.0000000000000132e-15 14.522878745280336 -1.6856190613914082 NHDDWSHDYDNRR ddPTM_PC-9_AZD4547_30min_R2 2 NHDDWSHDYDNRR 13 1 G3V1T9;J3KPD3;Q9Y580 G3V1T9 RBM7 RNA-binding protein 7 0 ; 85.522 0.0017153 26183000.0 3550.2 2623.1 7108.6 11129.6 10639.1 7297.5 4883.0 3378.8 2521.8 4720.799999999999 False True 4679.0897512526235 3470.9657774837315 7014.3353193232715 8563.842670605907 9162.044609233708 6841.186171389471 5317.577540375572 2856.684097099899 2655.0971996432622 4555.526228899691 1.0271238746402251 0.7619242219404548 1.5397420554458017 1.8798800051414382 2.0111934711539665 1.501733461216805 1.1672806330565113 0.6270810337952729 0.5828299665579042 1.0 12.15340200037409 -7.575458741699437 3.3614856049750177 0.7055404375974811 1.4664176784429328 0.44393488827630334 0.3574503149461096 0.251286936416464 5.823835911888064 0.21345764435326023 0.11731698918047868 2.657916041572296e-08 7.575458741699437 0.7608772408454517 NHDDWSHDYDNRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NHDDWSHDYDNRR 13 1 G3V1T9;J3KPD3;Q9Y580 G3V1T9 RBM7 RNA-binding protein 7 0 ; 88.155 0.0014368 17325500.0 5033.3 8154.700000000001 8295.3 9215.9 10860.5 10386.7 8723.2 14240.0 11921.5 8079.5 False True 5885.33827779355 8964.244723465199 8493.091412100433 8699.563001350927 8732.46298775158 9842.003167259661 7896.875345501098 13866.215088527168 12095.829384237815 9544.249392713189 0.6166371011100013 0.9392299336089426 0.8898647827229567 0.9114978709580703 0.9149449714105974 1.0311971913447484 0.8273961650174584 1.4528345308237334 1.2673421331040131 1.0 13.220416026032375 -7.7499024034461375 24.99900488106043 1.270066263253826 0.887655296975719 0.5692722681693263 0.14422619150088822 137.47136589293382 297882.62438952783 0.06587788213899191 0.037617930954127236 1.778679077664965e-08 7.7499024034461375 -0.382410966278107 NHDDWSHDYDNRR ddPTM_PC-9_Lapatinib_30min_R1 2 NHDDWSHDYDNRR 13 1 G3V1T9;J3KPD3;Q9Y580 G3V1T9 RBM7 RNA-binding protein 7 0 ; 92.24700000000001 0.0010042 17594600.0 4210.1 3177.0899999999997 1959.66 1860.15 3604.62 3212.69 2091.13 2872.76 3350.5 2099.8599999999997 False True 4150.063201962217 3169.7336433048295 1798.5443193063559 1996.9516362784927 3392.6033385555884 3075.290737846174 2199.3984794223275 3006.2389171259856 2973.1314076708645 2462.818003112429 1.6850872442533322 1.2870352739418924 0.7302790206314126 0.8108401163848935 1.3775290477283044 1.2486877771559743 0.8930414170445399 1.2206500493852162 1.2072071114932237 1.0 11.266094304415954 -4.8772204767397955 3.76981444290814 1.068668702142351 1.693331445375871 0.4804258547581097 0.19798616100551458 0.21731953341733912 5.208715063709645 0.053435231877326926 0.3125792037069184 1.326720755114365e-05 4.8772204767397955 0.6246627432335199 NHDEESLECLCR ddPTM_PC-9_AZD4547_30min_R2 2 NHDEESLECLCR 12 0 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73;C9JF13;A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3;O43432-4 Q04637-9;A0A0A0MSA7 EIF4G1;EIF4G3 Eukaryotic translation initiation factor 4 gamma 1;Eukaryotic translation initiation factor 4 gamma 3 0 ; 197.36 8.947000000000001e-06 14004600.0 37889.0 28412.0 45106.0 71814.0 56934.0 53004.0 41597.0 56599.0 49297.0 64472.0 False True 49936.91385984188 37595.62337305776 44507.86496826318 55258.39181523978 49029.69685237584 49689.651500969856 45299.052415933365 47852.92506563194 51902.73877817985 62214.854903749496 0.8026525809165286 0.6042869252242199 0.715389677226119 0.8881864612676214 0.7880705810248699 0.7986782510036075 0.7281066955153074 0.7691559377525446 0.8342499369077824 1.0 15.924971470150357 -14.522878745266826 0.1668105979838451 1.8987461737683329 0.7097526932290068 0.5211204861467365 0.06926207796234726 114.17360142271006 1.0652137565626052 33.88835406680719 0.27986382886999583 3.0000000000933316e-15 14.522878745266826 -1.188993480539326 NHDEESLECLCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NHDEESLECLCR 12 0 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73;C9JF13;A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3;O43432-4 Q04637-9;A0A0A0MSA7 EIF4G1;EIF4G3 Eukaryotic translation initiation factor 4 gamma 1;Eukaryotic translation initiation factor 4 gamma 3 0 ; 155.86 0.00028576 9971400.0 56734.0 52532.0 60915.0 72908.0 74433.0 77663.0 71193.0 81810.0 63573.0 52137.0 False True 66337.9456524226 57747.02978810674 62367.44462142399 68823.20113092534 59848.38797176133 73590.2155621022 64449.083647315165 79662.57418485996 64502.63485670014 61589.02538373509 1.077106598766566 0.9376188278400168 1.0126389276797108 1.117458844365813 0.9717378639923495 1.1948592318776403 1.0464377905927276 1.293454047835897 1.0473072833156813 1.0 15.910385677952917 -6.757195284587743 24.999679121229384 1.1303791812784008 1.0231888781209884 0.1984677832740438 0.09141752198352747 152.5927045278241 898840.0940077461 0.02915321464448218 0.02815977019451144 1.749060030523807e-07 6.757195284587743 -0.1071903031574124 NHDEESLECLCR ddPTM_PC-9_Lapatinib_30min_R1 1 NHDEESLECLCR 12 0 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73;C9JF13;A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3;O43432-4 Q04637-9;A0A0A0MSA7 EIF4G1;EIF4G3 Eukaryotic translation initiation factor 4 gamma 1;Eukaryotic translation initiation factor 4 gamma 3 0 215.02 7.8537e-11 4660800.0 27859.0 42489.0 41477.0 38343.0 43823.0 42121.0 34665.0 39614.0 42435.0 45938.0 False True 27461.725551285086 42390.61933101637 38066.92116585007 41162.87212849837 41245.417299332956 40319.583018846715 36459.78408285233 41454.611058016984 37655.52343963981 53878.32209146264 0.5096989751215094 0.7867843259679653 0.7065350160910452 0.7639969199230293 0.7655289863948557 0.7483451869640834 0.6767060047074037 0.7694116937725818 0.69889933423904 1.0 15.717417301841516 -14.522878745280336 0.27781243438265635 3.0003576330184796 0.7025880811096219 0.5658022627726842 0.07563084755821647 164.85053708744542 1.5823254721684274 190.0703239800127 0.08437482389290413 3.0000000000000132e-15 14.522878745280336 -2.297769551908858 NHEGDEDDSHVR ddPTM_PC-9_AZD4547_30min_R2 2 NHEGDEDDSHVR 12 0 Q9UNE7;Q9UNE7-2;H3BTA3;H3BS86;H3BUD0 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 0 ; 210.15 1.2753000000000002e-08 65637000.0 28840.1 29497.9 32864.0 56485.0 42321.0 41765.0 31448.6 35717.7 28173.7 47470.0 False True 38010.65188865439 39032.51931212589 32428.20188704386 43463.25593455062 36445.45966363503 39153.42794766446 34247.464475989196 30198.35017609362 29662.904264251487 45808.08974874349 0.8297803313157589 0.8520879068788619 0.7079143021442704 0.9488117966268789 0.7956118638331721 0.8547273672056677 0.7476291778119518 0.6592361816816855 0.6475472875413919 1.0 15.48331478157856 -7.334325763352887 5.913686587458835 0.733847307815896 0.8304105455794925 0.06188415008644588 0.10735348239754662 0.4410151030828829 27.689634077761994 0.043266404822996624 0.02898255532194842 4.63099419548609e-08 7.334325763352887 0.09656323776359643 NHEGDEDDSHVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NHEGDEDDSHVR 12 0 Q9UNE7;Q9UNE7-2;H3BTA3;H3BS86;H3BUD0 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 0 ;;; 184.31 0.00011204 41662070.0 20312.38 17768.68 15275.07 23451.0 24625.9 22868.489999999998 18160.1 24228.739999999998 16861.7 17983.510000000002 False True 23750.86474620787 19532.637121284868 15639.285599825558 22137.1164991678 19800.631673502303 21669.226126724156 16439.84386026165 23592.76124747201 17108.270463297642 21243.778005613163 1.1180151072908155 0.9194521386979205 0.7361819350443809 1.0420517712677375 0.9320673407653977 1.0200269519385194 0.7738662989190441 1.1105727635281344 0.8053308812950873 1.0 14.37475273821849 -4.760224841808489 24.556537438887865 0.9260442784671754 1.1180153859098414 0.19549356674580842 0.11647660703879315 39.416145699129494 796531.1488004887 0.027170517951479647 0.16291684836427592 1.7369013718809904e-05 4.760224841808489 0.191971107442666 NHEGDEDDSHVR ddPTM_PC-9_Lapatinib_30min_R1 2 NHEGDEDDSHVR 12 0 Q9UNE7;Q9UNE7-2;H3BTA3;H3BS86;H3BUD0 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 0 ; 199.8 2.5630000000000003e-06 52697000.0 42323.5 33218.5 30245.5 35925.8 31334.2 40129.1 26819.9 26815.1 34721.0 32376.5 False True 41719.95912882065 33141.584604188574 27758.831741006285 38567.903176955566 29491.183961407445 38412.871938501026 28208.503191221444 28061.027439335357 30810.35535166096 37972.73488602553 1.0986819688927423 0.8727731806429649 0.7310200812325979 1.0156735692784948 0.7766410307270386 1.0115908704968595 0.7428620370876301 0.7389783096624465 0.8113809933400289 1.0 15.212676288551673 -7.278789116869204 24.87580162254078 0.8015535321429392 0.9052386430072801 0.10655210143841887 0.12478316853353613 1613.0799010770002 2312800.8258057684 0.050406352628872976 0.03407641498702079 5.262727499600816e-08 7.278789116869204 0.10368511086434085 NHLLQFALES(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 2 NHLLQFALESPAK 13 0 Q9NS91;F8WE49 Q9NS91 RAD18 E3 ubiquitin-protein ligase RAD18 1 NHLLQFALES(1)PAK;NHLLQFALES(1)PAK 138.01 3.525e-05 8234100.0 111767.0 107341.0 94597.0 95236.0 88912.0 113570.0 127701.0 104216.0 117376.0 121681.0 True False 147306.58110198056 142036.87908233833 93342.58197141811 73280.81158153254 76568.10353283507 106468.44994651625 139066.14161038332 88111.81184543716 123580.25573214685 117420.98522681413 1.254516650643311 1.2096379434048807 0.7949395228724627 0.6240861583641203 0.6520819373550109 0.906724208972173 1.1843380579864724 0.7503923738609207 1.052454597391048 1.0 16.841330741293028 -5.251783278305136 20.80346226027846 0.857595470342314 1.232078172788975 0.4253145208849227 0.16751454362641394 67.27383460522735 144926.7608258456 0.04583338654269656 0.11677680431834887 5.600370015212925e-06 5.251783278305136 0.37448270244666093 NHLLQFALES(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NHLLQFALESPAK 13 0 Q9NS91;F8WE49 Q9NS91 RAD18 E3 ubiquitin-protein ligase RAD18 1 NHLLQFALES(1)PAK;NHLLQFALES(1)PAK 96.24700000000001 0.0018768 7685000.0 67182.0 75955.0 59840.0 74846.0 72667.0 60779.0 75509.0 79477.0 55607.0 58877.0 True False 78554.58569501633 83495.31043089261 61266.812544463755 70652.62127400591 58428.422994424254 57591.64224468547 68356.24088218123 77390.81296284219 56420.14717689148 69550.93402992446 1.1294540726256532 1.2004915763599744 0.880891297852356 1.0158400064563826 0.8400810687788215 0.8280498752167228 0.9828227591130665 1.1127214039935769 0.811206175212781 1.0 16.085782269030002 -5.258538265935376 24.982795150108924 0.9355126006394769 1.1649728429609756 0.49856141081215555 0.09266417430925197 201.64237781971312 1736410.1762920269 0.02413585795380635 0.05825602174145595 5.5139361663415575e-06 5.258538265935376 0.22946024232149864 NHLLQFALES(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 2 NHLLQFALESPAK 13 0 Q9NS91;F8WE49 Q9NS91 RAD18 E3 ubiquitin-protein ligase RAD18 1 NHLLQFALES(1)PAK;NHLLQFALES(1)PAK 147.53 6.2529e-05 6326300.0 52649.0 72994.0 52413.0 72856.0 67526.0 61711.0 62661.0 64929.0 63891.0 77773.0 True False 51898.2156053559 72824.98687773808 48103.80546003087 78214.07328049114 63554.253441224 59071.76438536714 65905.27997737218 67945.83837496799 56694.92277794332 91215.95942399166 0.5689598172631357 0.7983798815208605 0.5273617222665378 0.8574604024821476 0.6967448880936501 0.6476033882490749 0.7225191774942592 0.7448898066087418 0.6215460883814526 1.0 16.476998644372635 -11.141242740143085 2.8905908713173276 1.0242027117203851 0.6926869050572051 0.4890407261773121 0.09575345166583299 52500366.50764668 52419653.001040496 9583170.96315786 0.022501788838690834 7.223659388716823e-12 11.141242740143085 -0.33151580666318003 NHLS(ph)PQQGGATPQVPS(ph)PCCR ddPTM_PC-9_AZD4547_30min_R2 2 NHLSPQQGGATPQVPSPCCR 20 0 Q9H4L4;A0A087X0R7 Q9H4L4 SENP3;SENP3-EIF4A1 Sentrin-specific protease 3 2 NHLS(1)PQQGGATPQVPS(1)PCCR;NHLS(1)PQQGGATPQVPS(1)PCCR 135.78 2.5559e-05 22713000.0 53200.0 49618.0 60659.0 90269.0 67211.0 68202.0 57373.0 74571.0 45899.0 65491.0 True False 70116.49337125773 65656.04816712585 59854.6220261135 69458.87669214747 57879.91279630858 63937.318158424794 62479.08585377174 63047.765421107055 48325.127435334325 63198.18002390895 1.1094701357654835 1.0388914386820483 0.9470940777640983 1.0990645089125983 0.9158477787558379 1.01169556044551 0.9886216000228937 0.9976199535691536 0.7646601123173501 1.0 15.947595391934618 -1.522878745398162 0.2772398466207597 0.9298073917935701 2.1652402634757415 0.28531428595075314 0.07895862924857888 70.4949690661743 0.9913532671498781 0.08679355007410737 42.04573074030951 0.029999999991860975 1.522878745398162 1.2354328716821714 NHLS(ph)PQQGGATPQVPS(ph)PCCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NHLSPQQGGATPQVPSPCCR 20 0 Q9H4L4;A0A087X0R7 Q9H4L4 SENP3;SENP3-EIF4A1 Sentrin-specific protease 3 2 NHLS(1)PQQGGAT(0.002)PQVPS(0.998)PCCR;NHLS(1)PQQGGAT(0.007)PQVPS(0.993)PCCR 105.37 0.00032211 13431600.0 42961.0 38963.0 44922.0 42910.0 52938.0 44109.0 53664.0 47055.0 36998.0 37378.0 True False 50233.44878157243 42830.98914250368 45993.110847633725 40505.89181609703 42565.178918612706 41795.84639054332 48580.55742628521 45819.85610889368 37539.02575666071 44154.33551591481 1.1376787396894805 0.9700290728430472 1.0416442759297364 0.9173706577805308 0.9640090473849546 0.9465853330638072 1.1002443329438176 1.0377204316069608 0.850177571874687 1.0 15.430267482660316 -4.758234602754051 24.88316524980951 0.9840911266596402 1.1376789645482053 0.332080343581469 0.06657725439430558 105.30051924725822 817450.0752009489 0.016604104118011293 0.11535625418421994 1.7448793270327975e-05 4.758234602754051 0.15358783788856512 NHLS(ph)PQQGGATPQVPS(ph)PCCR ddPTM_PC-9_Lapatinib_30min_R1 1 NHLSPQQGGATPQVPSPCCR 20 0 Q9H4L4;A0A087X0R7 Q9H4L4 SENP3;SENP3-EIF4A1 Sentrin-specific protease 3 2 NHLS(1)PQQGGATPQVPS(1)PCCR 103.64 0.00038756 11329000.0 20134.0 23100.0 23819.0 22761.0 24994.0 29228.0 13683.0 23311.0 22312.0 19084.0 True False 19846.885467876597 23046.51336925976 21860.6937639989 24434.919868470177 23523.902060094653 27977.986573795763 14391.438788566817 24394.1141609894 19798.987604223945 22382.643972168407 0.886708714687823 1.0296600079024103 0.9766805830080431 1.09169050353719 1.0509885288505387 1.2499857750757621 0.6429731360808751 1.089867407591442 0.8845687591172384 1.0 14.450092845722297 -10.049760215526359 5.6019998332955465 0.9999999991679861 0.9953298879760243 0.0 0.1535963662514287 0.0 0.0 0.14337527101720132 0.03477361097091055 8.917431551743988e-11 10.049760215526359 -0.004670111191961812 NHLS(ph)PQQGGATPQVPSPCCR ddPTM_PC-9_AZD4547_30min_R2 3 NHLSPQQGGATPQVPSPCCR 20 0 Q9H4L4;A0A087X0R7 Q9H4L4 SENP3;SENP3-EIF4A1 Sentrin-specific protease 3 1 NHLS(1)PQQGGATPQVPSPCCR;NHLS(1)PQQGGATPQVPSPCCR;NHLS(0.996)PQQGGAT(0.004)PQVPSPCCR 140.27 7.5771e-05 58675800.0 66597.2 65114.7 75371.0 132321.0 94154.0 75829.4 61106.0 84007.5 57331.1 92853.0 True False 87773.72429218679 86161.75338764058 74371.53129346346 101816.437789071 81082.3423163418 71087.77563066267 66544.31562199251 71026.07117530472 60361.5049022396 89602.24473225347 0.9795929170577076 0.9616026210627462 0.830018617454262 1.1363157038455407 0.9049141855611925 0.7933704768567446 0.7426634881842311 0.7926818283129238 0.6736606329742061 1.0 16.451247254952023 -6.661409115983682 3.9606940540113476 0.7834011772391674 0.9706937223453579 0.38276575523190526 0.10432752241364654 0.2178233008326913 6.37832089998939 0.03438774103548422 0.033951498350065355 2.1806746952671364e-07 6.661409115983682 0.18729254510619053 NHLS(ph)PQQGGATPQVPSPCCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NHLSPQQGGATPQVPSPCCR 20 0 Q9H4L4;A0A087X0R7 Q9H4L4 SENP3;SENP3-EIF4A1 Sentrin-specific protease 3 1 NHLS(1)PQQGGATPQVPSPCCR;NHLS(1)PQQGGATPQVPSPCCR;NHLS(1)PQQGGATPQVPSPCCR;NHLS(0.97)PQQGGAT(0.03)PQVPS(0.001)PCCR 235.85 8.603199999999999e-102 35717300.0 79022.4 71583.9 80534.7 112309.0 94663.6 79846.8 96269.0 94746.2 69179.9 77637.5 True False 92399.3315564565 78690.27651048604 82454.95267755058 106016.69084069057 76114.94712833846 75659.49324574205 87149.70339279702 92259.21264189691 70191.52516198727 91712.56417188815 1.0074882584602172 0.8580097745713916 0.899058416064053 1.155966925556607 0.8299293320998358 0.8249632308168884 0.9502482476605997 1.0059604534552564 0.7653425219955028 1.0 16.48483176906023 NHLS(ph)PQQGGATPQVPSPCCR ddPTM_PC-9_Lapatinib_30min_R1 5 NHLSPQQGGATPQVPSPCCR 20 0 Q9H4L4;A0A087X0R7 Q9H4L4 SENP3;SENP3-EIF4A1 Sentrin-specific protease 3 1 NHLS(1)PQQGGATPQVPSPCCR;NHLS(0.997)PQQGGAT(0.003)PQVPSPCCR;NHLS(0.64)PQQGGAT(0.36)PQVPSPCCR;NHLS(0.994)PQQGGAT(0.006)PQVPSPCCR;NHLS(0.996)PQQGGAT(0.004)PQVPSPCCR 220.16 4.7268e-87 43679200.0 88999.6 93688.4 90821.90000000001 98541.5 97301.70000000001 97566.0 89926.3 85605.40000000001 96121.6 67517.70000000001 True False 87730.44938347205 93471.470265998 83354.87396467263 105788.57063480753 91578.6053085024 93393.32961745442 94582.24380123481 89582.93940187719 85295.37320267888 79188.04448332005 1.1078749318270051 1.180373513146755 1.0526194264366546 1.3359159368696185 1.1564700947728577 1.1793867398395794 1.1944005489510146 1.131268488651045 1.0771243785499118 1.0 16.272995013558983 -8.402842435560274 1.6533572105805956 1.0019539523659649 1.1740555038445053 0.3950383514861875 0.06828126956829388 0.3570433681945884 2.049403930110597 0.0634806189662557 0.018601198294770898 3.955100872880821e-09 8.402842435560274 0.17210155147854045 NHLSPQQGGAT(ph)PQVPSPCCR ddPTM_PC-9_AZD4547_30min_R2 1 NHLSPQQGGATPQVPSPCCR 20 0 Q9H4L4;A0A087X0R7 Q9H4L4 SENP3;SENP3-EIF4A1 Sentrin-specific protease 3 1 NHLS(0.068)PQQGGAT(0.932)PQVPSPCCR 157.73 3.4816999999999995e-05 8607100.0 18421.0 14560.0 25276.0 37182.0 31651.0 23549.0 17627.0 26008.0 20542.0 29511.0 True False 24278.494819397372 19266.23526368157 24940.823724954986 28610.264356173535 27256.80498602851 22076.47730730397 19195.76885197629 21989.06120438445 21627.80818267583 28477.82887244932 0.8525402314951557 0.6765345543009621 0.8757979351819132 1.0046504768434905 0.9571237016736875 0.7752163062073073 0.6740601236826415 0.7721466865635116 0.7594612735242434 1.0 14.797551540097139 -6.859006912670706 14.450034275917812 0.7741947078956295 0.8698218031361851 0.09045396419581397 0.11168312707947796 1.7689323629354265 253.46869563366403 0.0412845704815371 0.03641074847495873 1.383544356903667e-07 6.859006912670706 0.09562709524055557 NHLSPQQGGAT(ph)PQVPSPCCR ddPTM_PC-9_Lapatinib_30min_R1 2 NHLSPQQGGATPQVPSPCCR 20 0 Q9H4L4;A0A087X0R7 Q9H4L4 SENP3;SENP3-EIF4A1 Sentrin-specific protease 3 1 NHLS(0.102)PQQGGAT(0.898)PQVPS(0.001)PCCR;NHLS(0.005)PQQGGAT(0.985)PQVPS(0.011)PCCR 186.17 3.4666e-11 16209900.0 33286.1 37589.7 38301.2 32095.6 32518.6 34602.4 32354.6 33845.1 31431.2 29538.8 True False 32811.43411007687 37502.663359154285 35152.22318290754 34456.017491782935 30605.919882027418 33122.53601413407 34029.76287572635 35417.6669036121 27891.08727079078 34644.54222202309 0.9470881127480757 1.0824984529688582 1.014653995357506 0.9945583137155638 0.8834268810910028 0.9560679371043471 0.9822546552251474 1.0223159156393051 0.80506439057696 1.0 15.080340472766114 -6.024677391017694 12.64905316073117 0.9448136665862976 1.0187151127761493 0.20845943649879395 0.06564606293761434 2.5169346762794067 1289.7040144553682 0.018727984673576708 0.024681494201006557 9.447624179334396e-07 6.024677391017694 0.07390144618985173 NHLSPQQGGATPQVPS(ph)PCCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NHLSPQQGGATPQVPSPCCR 20 0 Q9H4L4;A0A087X0R7 Q9H4L4 SENP3;SENP3-EIF4A1 Sentrin-specific protease 3 1 NHLS(0.001)PQQGGAT(0.01)PQVPS(0.989)PCCR 169.17 2.6635e-08 5715600.0 8104.9 4848.0 5548.2 11133.0 6481.1 9789.2 9247.3 9892.0 6798.2 7375.2 True False 9476.899490928205 5329.277400684185 5680.490129665669 10509.254103672993 5211.174979965635 9275.837119098293 8371.328799345685 9632.345481440356 6897.61081406916 8712.265377948923 1.0877652458698743 0.6116982402961221 0.6520106864562697 1.2062596406064854 0.5981423606718086 1.0646871642105613 0.9608670576695056 1.1056074469242168 0.7917126619589984 1.0 13.088832184265554 NHS(ph)NAQFIESYVCR ddPTM_PC-9_AZD4547_30min_R2 2 NHSNAQFIESYVCR 14 0 P41229-4;P41229-3;P41229-2;P41229-5;P41229 P41229-4 KDM5C Lysine-specific demethylase 5C 1 NHS(1)NAQFIESYVCR;NHS(1)NAQFIESYVCR 117.3 7.4875e-05 12868800.0 20314.2 25315.0 25826.0 40764.0 30229.0 38805.0 23758.0 33793.0 23995.7 25894.0 True False 26773.693038391095 33497.57868819363 25483.530365591374 31366.489597521828 26032.225140521798 36378.51721559007 25872.415974655512 28571.06833588757 25264.063713807525 24987.458941520188 1.071485223889766 1.3405756370261674 1.019852815975893 1.2552892901567505 1.0418116224401508 1.455871015165213 1.035416047514333 1.1434163194726739 1.0110697439437397 1.0 14.608916575937506 -8.011061048836742 1.5559407570003931 1.0028664187815644 1.1874890619971816 0.20056763514277476 0.13535541109942428 0.6258955744555276 2.7149257917157428 0.11239854547292821 0.03727676653402801 9.748525929185516e-09 8.011061048836742 0.18462264321561728 NHS(ph)NAQFIESYVCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NHSNAQFIESYVCR 14 0 P41229-4;P41229-3;P41229-2;P41229-5;P41229 P41229-4 KDM5C Lysine-specific demethylase 5C 1 NHS(1)NAQFIESYVCR 82.449 0.016253999999999998 0.0 9554.8 9211.4 11767.0 13765.0 12950.0 18794.0 14100.0 13365.0 15017.0 13795.0 True False 11172.238924097861 10125.846915978194 12047.569906596005 12993.791676732124 10412.540462352834 17808.40955505387 12764.345924840145 13014.18291138803 15236.595215627161 16295.924298840084 0.685584856631488 0.621372972179242 0.7392995748914672 0.7973645089684787 0.6389659323033294 1.0928137139371372 0.7832845618796038 0.7986158178406829 0.9349942314540376 1.0 13.992223563079433 -3.1798991726296277 0.1598183519948169 1.031213019632778 4.598372649394272e-09 0.4674141529738086 0.10775506049614207 34.75794546386731 0.5798577208316876 0.3627847145681639 7.699829283359773 0.0006608468547840176 3.1798991726296277 -1.0312130150344054 NHS(ph)NAQFIESYVCR ddPTM_PC-9_Lapatinib_30min_R1 2 NHSNAQFIESYVCR 14 0 P41229-4;P41229-3;P41229-2;P41229-5;P41229 P41229-4 KDM5C Lysine-specific demethylase 5C 1 NHS(1)NAQFIESYVCR;NHS(1)NAQFIESYVCR 100.58 0.0010898 8435500.0 18250.0 25291.0 25277.0 20245.5 28266.0 25299.0 26834.0 28779.0 28318.0 24321.0 True False 17989.75165335989 25232.44024337442 23198.82263204166 21734.42160700816 26603.449453094137 24217.020744849426 28223.33322022962 30116.177402904792 25128.528638240125 28524.85244430455 0.6306694027071763 0.8845774151730096 0.8132845797305319 0.761946854920464 0.9326410892059127 0.8489797025991189 0.9894295956600072 1.055787316050358 0.8809345705575224 1.0 14.799931803191516 -2.9982392766787065 0.23956876542921174 1.0193307841799766 1.151303063775806e-19 0.6012516549263446 0.0751374960749768 17.89614825490514 0.4395752005317537 0.10770775697265174 6.26516783217653 0.0010040624447207951 2.9982392766787065 -1.0193307841799766 NHS(ph)PSPPVTPTGAAPSLASPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NHSPSPPVTPTGAAPSLASPK 21 0 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 NHS(0.414)PS(0.414)PPVT(0.169)PT(0.003)GAAPSLASPK 65.155 0.0024924 4079200.0 15343.0 15116.0 13151.0 15160.0 18430.0 20898.0 20902.0 23767.0 18915.0 20819.0 True False 17940.266861936772 16616.61658183623 13464.569715445232 14310.634349383143 14818.77380086199 19802.07209117355 18922.01124262472 23143.14143321805 19191.59609133568 24593.31989688667 0.7294772294735155 0.6756556923386244 0.5474889023482244 0.5818911155299029 0.6025528014515005 0.8051809261294708 0.769396377632615 0.941033643698824 0.7803580879605112 1.0 14.585978879651472 -7.093319971495704 1.5170289135031216 0.8879373816930262 0.6226292211009823 0.6862688894954021 0.07918249851446417 0.23810375234334036 1.0933878699958965 0.041963070987264504 0.02885276393043647 8.066405095163664e-08 7.093319971495704 -0.2653081605920439 NHSDSSTSESEVS(ph)SVSPLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NHSDSSTSESEVSSVSPLK 19 0 Q9NY27-2;Q9NY27-3;Q9NY27;H7C559;C9IZ04 Q9NY27-2 PPP4R2 Serine/threonine-protein phosphatase 4 regulatory subunit 2 1 NHSDSS(0.01)T(0.001)S(0.01)ESEVS(0.55)S(0.098)VS(0.33)PLK 219.89 4.028e-28 5979900.0 21740.0 32344.0 34842.0 35428.0 41965.0 28234.0 37375.0 33939.0 26931.0 22922.0 True False 25420.152615427603 35554.89856595072 35672.76541902081 33443.08401912574 33742.25949827312 26753.35933688365 33834.56942843263 33048.13721134294 27324.814926553565 27077.57714954783 0.9387897770555182 1.3130753305431708 1.3174282625805949 1.2350840636302722 1.246132891134116 0.9880263359283017 1.2495419823408254 1.2204983122684894 1.0091307200655457 1.0 14.724811034610441 NHSDSSTSESEVSS(ph)VSPLK ddPTM_PC-9_AZD4547_30min_R2 1 NHSDSSTSESEVSSVSPLK 19 0 Q9NY27-2;Q9NY27-3;Q9NY27;H7C559;C9IZ04 Q9NY27-2 PPP4R2 Serine/threonine-protein phosphatase 4 regulatory subunit 2 1 NHSDSSTSESEVS(0.007)S(0.734)VS(0.26)PLK 273.01 1.1032999999999997e-91 9079400.0 31628.0 31507.0 54572.0 63779.0 50376.0 64053.0 59287.0 88836.0 64094.0 59576.0 True False 41685.046096732 41691.021597034 53848.33962328866 49075.73692572728 43382.161953055904 60047.75578431101 64563.428145862505 75108.43744819665 67481.87798950572 57490.26237352313 0.7250801157576532 0.7251840551041667 0.9366514849667525 0.8536356401867611 0.7546001733510153 1.04448567992561 1.123032414191884 1.306454942929387 1.173796660572977 1.0 15.81102999447406 -6.960358686166068 2.6801453840336675 1.1755275973621644 0.8046078003731465 0.7574761795169308 0.09411749488571744 0.1337409834471722 1.9484969482334071 0.03867315928396398 0.03182953244930779 1.0955729827209089e-07 6.960358686166068 -0.3709197969890179 NHSDSSTSESEVSS(ph)VSPLK ddPTM_PC-9_Lapatinib_30min_R1 2 NHSDSSTSESEVSSVSPLK 19 0 Q9NY27-2;Q9NY27-3;Q9NY27;H7C559;C9IZ04 Q9NY27-2 PPP4R2 Serine/threonine-protein phosphatase 4 regulatory subunit 2 1 NHSDSSTSESEVS(0.001)S(0.884)VS(0.115)PLK;NHSDSS(0.001)T(0.001)S(0.007)ESEVS(0.079)S(0.577)VS(0.334)PLK 157.84 7.1181e-06 34128000.0 57938.0 67648.0 137033.0 97260.0 141788.0 150809.0 120767.0 138887.0 147353.0 115661.0 True False 57111.793495472084 67491.36521228061 125766.6757026767 104412.82484984871 133448.30860593353 144359.25062294962 127019.72434253067 145340.19705192134 130756.55344412026 135652.84974140508 0.42101432888689216 0.49753002123390216 0.9271215160051972 0.7697060920496016 0.9837486559281721 1.0641814816138515 0.9363586875223651 1.0714127814416228 0.9639056878892067 1.0 17.04955982994165 -4.983341786676777 0.8388297440140688 1.0085273021768972 0.13493764393611707 0.8682808980218711 0.07906197884911323 0.5896642416166743 0.3931822670154897 0.028860632106733647 0.45122910237276154 1.0391020779916636e-05 4.983341786676777 -0.8735896582407802 down NHSDSSTSESEVSSVS(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 3 NHSDSSTSESEVSSVSPLK 19 0 Q9NY27-2;Q9NY27-3;Q9NY27;H7C559;C9IZ04 Q9NY27-2 PPP4R2 Serine/threonine-protein phosphatase 4 regulatory subunit 2 1 NHSDSSTSESEVSS(0.081)VS(0.919)PLK;NHSDSSTSESEVS(0.004)S(0.112)VS(0.884)PLK;NHSDSSTSESEVS(0.027)S(0.325)VS(0.647)PLK 237.66 1.0584000000000001e-43 29523100.0 85909.0 84872.0 218483.0 190128.0 214176.0 236599.0 213226.0 318204.0 255397.0 251786.0 True False 113226.27498179318 112305.21423758125 215585.7726657436 146296.92704831806 184441.35934686539 221804.4271277257 232202.70092650436 269032.88340049004 268896.7640166909 242971.04877769362 0.46600726939031145 0.46221644431528514 0.8872899621180539 0.6021167039624233 0.7591083805034732 0.9128841820601667 0.9556805310535504 1.1072631276602904 1.106702898840915 1.0 17.890424894139592 -6.086729315858463 0.4686993053762914 1.1067856337241753 0.3780546567788421 0.7886079388271632 0.10613040590737596 0.7404864593512269 0.2846563271447988 0.09283620268446648 0.2645252938637989 8.18975074366391e-07 6.086729315858463 -0.7287309769453332 down NHSDSSTSESEVSSVS(ph)PLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NHSDSSTSESEVSSVSPLK 19 0 Q9NY27-2;Q9NY27-3;Q9NY27;H7C559;C9IZ04 Q9NY27-2 PPP4R2 Serine/threonine-protein phosphatase 4 regulatory subunit 2 1 NHSDSSTSESEVS(0.003)S(0.067)VS(0.93)PLK;NHSDSSTS(0.001)ESEVS(0.007)S(0.095)VS(0.898)PLK 173.01 1.0299e-08 19736600.0 46707.0 81024.0 116716.0 124280.0 143022.0 108067.0 129579.0 90353.0 89514.0 77117.0 True False 54613.57259469997 89067.52725103841 119498.95208789475 117316.99452119658 114997.86579201749 102399.77627891912 117304.33904928094 87981.32948691667 90822.97290614949 91097.70164216374 0.5995054936646456 0.9777143182042073 1.311766926429083 1.2878150865103437 1.2623574878292185 1.1240654202358529 1.2876761645431865 0.9657908805703098 0.9969842407540269 1.0 16.475127035428798 -4.851459262402355 3.144890854387422 1.1652893981849055 0.5573406426243583 0.6373421547123257 0.12673388380332692 0.19503190677283622 3.132592260331923 0.034316858845625915 0.2699282454494049 1.4077992762541241e-05 4.851459262402355 -0.6079487555605472 NHSDSSTSESEVSSVS(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 2 NHSDSSTSESEVSSVSPLK 19 0 Q9NY27-2;Q9NY27-3;Q9NY27;H7C559;C9IZ04 Q9NY27-2 PPP4R2 Serine/threonine-protein phosphatase 4 regulatory subunit 2 1 NHSDSSTSESEVSS(0.008)VS(0.992)PLK;NHSDSSTSESEVS(0.002)S(0.104)VS(0.894)PLK 195.86 8.8052e-15 46424000.0 114553.0 137672.0 274731.0 204253.0 294075.0 315868.0 267457.0 296528.0 306856.0 270799.0 True False 112919.45321355251 137353.22894254242 252143.67767232851 219274.4469880343 276778.08667369536 302359.06196427124 281304.6147828484 310305.77340868546 272294.6459430682 317606.2463330136 0.355532847723515 0.4324638779255181 0.7938876536072692 0.6903971490476376 0.871450388237927 0.951993436701004 0.8857024004745091 0.977014076364627 0.8573340388827376 1.0 18.276879760548184 -4.919509664921486 0.6560423095081821 0.941126836548959 1.115891461752411e-19 0.900137326731169 0.06714487335743455 0.7768107446486415 0.28581148566270387 0.03042299291189315 0.5341004391231315 1.2036226037096724e-05 4.919509664921486 -0.941126836548959 down NHSGNDERDEEDEER ddPTM_PC-9_AZD4547_30min_R2 2 NHSGNDERDEEDEER 15 1 Q8IWS0-5;Q8IWS0;Q8IWS0-3;A0A0D9SGE8 Q8IWS0-5;A0A0D9SGE8 PHF6 PHD finger protein 6 0 ; 72.891 0.008432799999999999 2911300.0 570.89 653.11 440.7 627.86 523.8 872.98 497.95 944.71 459.48 0.0 False True 752.4211447503267 864.2150352378484 434.85603005173516 483.1165773403019 451.0794114461385 818.3924225967222 542.2665853430298 798.726776776148 483.76717475298847 0.0 0.0 NHSGNDERDEEDEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NHSGNDERDEEDEER 15 1 Q8IWS0-5;Q8IWS0;Q8IWS0-3;A0A0D9SGE8 Q8IWS0-5;A0A0D9SGE8 PHF6 PHD finger protein 6 0 ; 78.529 0.0053183 5300600.0 736.87 1695.26 635.23 1407.74 1649.44 1627.81 995.04 414.74 590.11 1470.75 False True 861.6075371540996 1863.5542092169692 650.37629232319 1328.8688917546588 1326.2440726041136 1542.444778004269 900.7826077342502 403.8535144533536 598.7392423715618 1737.3853325494067 0.49592195871125083 1.0726199734185764 0.3743419954909139 0.7648671062536838 0.7633563192674178 0.8877965924467167 0.5184702500121022 0.2324490180084268 0.3446208685858899 1.0 10.762702047752104 -7.452652085983621 7.3942835416190515 0.44864806678293645 0.7283997176625261 0.10499270280396344 0.262197768166945 0.4377785121289173 40.757155534430225 0.10518720154429935 0.0702773161743608 3.526532690204912e-08 7.452652085983621 0.27975165087958964 NHSGNDERDEEDEER ddPTM_PC-9_Lapatinib_30min_R1 2 NHSGNDERDEEDEER 15 1 Q8IWS0-5;Q8IWS0;Q8IWS0-3;A0A0D9SGE8 Q8IWS0-5;A0A0D9SGE8 PHF6 PHD finger protein 6 0 ; 84.29700000000001 0.002771 5035200.0 1685.93 1105.9299999999998 1121.21 1546.08 1544.27 0.0 1388.1 2272.1 1603.86 1733.23 False True 1661.8883290383026 1103.369287033137 1029.02844179576 1659.7838807716876 1453.4390747516356 0.0 1459.9690259745362 2377.6700607088483 1423.2163974054602 2032.8164961161942 0.8175299306225771 0.5427785976457706 0.5062082306798349 0.816494692926191 0.7149878395460237 0.0 0.7182001074685718 1.169643234030969 0.7001204487097542 1.0 10.989264272549141 -7.529822013141267 24.69097310934659 0.9497135999109488 0.5621944809649619 0.34215749803766626 0.2420700680341251 175.24054587118852 623160.3358331792 0.11440612025407075 0.0662494619801107 2.952418968289438e-08 7.529822013141267 -0.3875191189459869 NHSGS(ph)RTPPVALNSSR ddPTM_PC-9_AZD4547_30min_R2 1 NHSGSRTPPVALNSSR 16 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 NHS(0.083)GS(0.756)RT(0.161)PPVALNSSR 57.794 0.026476999999999997 12085000.0 3993.7 3083.1 8598.9 20537.0 9782.7 7245.6 3815.4 6166.5 4101.2 8242.8 True False 5263.613525879557 4079.6517816934515 8484.872967578549 15802.511943487043 8424.540966693663 6792.531486593981 4154.963208590814 5213.609117073087 4317.981059234257 7954.222080913052 0.6617383161214623 0.512891360109618 1.0667131092478352 1.9866822654357041 1.0591282065042147 0.8539529595098101 0.5223594672521229 0.6554517920217064 0.5428539730611348 1.0 12.957505127237598 -6.957089619772009 3.673386320807372 0.6532239896063012 1.0767444042185708 0.17466201940403314 0.3833741131610195 0.42267078654904955 11.993923129470724 0.16155697186044216 0.13653487043384444 1.1038508088895429e-07 6.957089619772009 0.4235204146122695 NHSPS(ph)PPVTPTGAAPSLASPK ddPTM_PC-9_AZD4547_30min_R2 1 NHSPSPPVTPTGAAPSLASPK 21 0 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 NHS(0.241)PS(0.758)PPVTPTGAAPSLASPK 144.44 9.925899999999999e-05 5027800.0 31377.0 25675.0 29187.0 43330.0 34440.0 36100.0 25441.0 36036.0 29828.0 38059.0 True False 41354.23331785633 33973.94164800993 28799.961309552968 33340.93794182665 29658.600477672822 33842.66129320451 27705.199714252492 30467.464224899988 31404.647184931087 36726.56599425801 1.1260032676161944 0.9250508651781265 0.7841724520080554 0.9078152840927005 0.8075516911194414 0.9214763312882457 0.7543640131937204 0.8295756327902643 0.8550934816459842 1.0 15.16453638711747 -4.812575794502585 3.13866735305106 0.8499444304914897 1.1575815793664246 0.5782144873671524 0.06860413689354952 0.20430653460008338 3.144397916016512 0.016139319863620803 0.15096520141220096 1.5396577964635277e-05 4.812575794502585 0.3076371488749349 NHSVNEEEQEEQGEGS(ph)EDEWEQVGPR ddPTM_PC-9_AZD4547_30min_R2 2 NHSVNEEEQEEQGEGSEDEWEQVGPR 26 0 Q14694;Q14694-3;Q14694-2;H3BNA1 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 NHSVNEEEQEEQGEGS(1)EDEWEQVGPR;NHSVNEEEQEEQGEGS(1)EDEWEQVGPR 168.69 1.5578e-13 141353000.0 58673.0 46284.0 61696.0 91386.0 71158.0 71806.0 55586.0 62678.0 50542.0 69318.0 True False 77329.7935257858 61244.39786704931 60877.8707285497 70318.3695996255 61278.93997648789 67315.95946869359 60533.046315649524 52992.55529715505 53213.54693646199 66891.19791875708 1.15605335129006 0.915582315350876 0.9101028628981814 1.051235017274334 0.9160987077988112 1.0063500365242735 0.9049478585982288 0.7922201567015936 0.7955239043721818 1.0 16.029528761501062 -7.473511043447955 4.222164011473753 0.8449978180303898 0.9838105043068199 0.30112093217208113 0.08879822887228522 0.2496544392554622 9.382858922896103 0.03918461465907305 0.024477595657321775 3.361158220243855e-08 7.473511043447955 0.13881268627643017 NHSVNEEEQEEQGEGS(ph)EDEWEQVGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NHSVNEEEQEEQGEGSEDEWEQVGPR 26 0 Q14694;Q14694-3;Q14694-2;H3BNA1 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 NHSVNEEEQEEQGEGS(1)EDEWEQVGPR 165.94 2.4995e-13 49328000.0 23892.0 26012.0 25153.0 35122.0 28995.0 34765.0 30756.0 30345.0 26119.0 25901.0 True False 27936.44371149015 28594.299452680887 25752.742913283713 33154.22820706034 23313.63789234908 32941.862199715215 27842.569025842797 29548.47590318517 26500.940962706652 30596.6462677968 0.9130557469265337 0.9345566570404352 0.8416851535911198 1.0835902705439784 0.7619671021554693 1.076649444236206 0.9099876104770119 0.965742311904464 0.8661387503309175 1.0 14.901085905735997 NHSVNEEEQEEQGEGS(ph)EDEWEQVGPR ddPTM_PC-9_Lapatinib_30min_R1 2 NHSVNEEEQEEQGEGSEDEWEQVGPR 26 0 Q14694;Q14694-3;Q14694-2;H3BNA1 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 NHSVNEEEQEEQGEGS(1)EDEWEQVGPR;NHSVNEEEQEEQGEGS(1)EDEWEQVGPR 170.59 9.0405e-14 143618000.0 60018.0 44685.0 45446.0 38666.0 43176.0 40017.0 27446.0 43882.0 45581.0 42597.0 True False 59162.13231404675 44581.534627938236 41709.605306633144 41509.626625994824 40636.47256728201 38305.56619418315 28867.0195856906 45920.91791911699 40447.187790791126 49959.834693065284 1.1841939165234827 0.8923475208000721 0.8348627565099346 0.8308599674321301 0.813382846779567 0.7667272405827272 0.5778045456523 0.9191567226200427 0.8095941077324147 1.0 15.608481082918669 -3.8401533854350776 1.1575146776876601 0.8004136276017826 3.575454955654842 0.5250605454027013 0.10307307320408067 8.900855283305182 1.918406362428758 0.030646404262235465 50.01142397614492 0.00014449293561080235 3.8401533854350776 2.7750413280530593 NHT(ph)VVSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NHTVVSPR 8 0 A0A087WXL3;O75417-2;O75417 A0A087WXL3 POLQ DNA polymerase theta 1 NHT(0.982)VVS(0.018)PR 105.17 0.0080663 1693700.0 5919.0 5931.5 6645.6 7631.3 8789.0 7337.9 8625.4 6521.7 6496.1 5912.5 True False 6920.969794421155 6520.340120082138 6804.056307578348 7203.743002008413 7066.858542364412 6953.087606365316 7808.339669511781 6350.512285312333 6591.093173086211 6984.389446675751 0.9909198001144136 0.9335590705334338 0.974180543557285 1.0314062606341439 1.011807631335322 0.995518314013069 1.1179702576906263 0.9092437261405699 0.9436892406140481 1.0 12.769918289952917 -1.5659825229315132 9.097221435732193 0.991626953827749 1.114527740521706 0.0 0.05549712689161693 0.0 0.0 0.013097038691878013 0.0 0.027165485871758235 1.5659825229315132 0.12290078669395699 NHTVVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 NHTVVSPR 8 0 A0A087WXL3;O75417-2;O75417 A0A087WXL3 POLQ DNA polymerase theta 1 NHT(0.233)VVS(0.767)PR;NHT(0.216)VVS(0.784)PR 72.096 0.01905 3300600.0 15989.599999999999 15173.0 14329.5 14475.8 13249.0 16535.2 11407.400000000001 12972.0 15836.3 10320.9 True False 15761.585371866482 15137.867850726334 13151.383823469594 15540.398621853188 12469.719868536215 15828.028041433836 11998.01935516312 13574.726476614229 14052.64913036803 12104.853813265201 1.302088039641918 1.2505618063835997 1.086455402630104 1.2838154728331472 1.030142128182595 1.3075769675209596 0.9911742463188605 1.1214283696460883 1.1609102717926525 1.0 13.563298035990732 -1.5228787452803696 0.12820995045060682 0.9814584479674213 1.9352364495347887 0.3396391630761978 0.0971516960465299 100.6225324697871 0.8788482981593707 0.520086556617747 17.301171463068957 0.02999999999999779 1.5228787452803696 0.9537780015673674 NIDDGTSDRPYSHALVAGIDR ddPTM_PC-9_AZD4547_30min_R2 2 NIDDGTSDRPYSHALVAGIDR 21 1 K7ELC7;P61353 K7ELC7 RPL27 60S ribosomal protein L27 0 ; 76.329 0.00060498 38663000.0 125915.0 141174.0 205884.0 222189.0 195385.0 224195.0 181813.0 241912.0 185703.0 183367.0 False True 165953.3508052992 186805.73469196307 203153.84363778404 170966.75883583032 168259.16534059567 210176.05120858643 197994.00478154927 204530.05898473703 195518.88145981182 176947.3771425706 0.9378683848565145 1.0557134991690178 1.148103164445881 0.9662011474636238 0.9508994598152499 1.1877884521523183 1.1189428630073501 1.1558807046907649 1.1049549567625279 1.0 17.43296085156333 -6.762821943243494 24.999977350380764 1.123595276680253 1.0192430460984228 0.3219819864602439 0.07269744833501464 45.92013674394544 830330.7335147685 0.02533197489560547 0.02356603618358292 1.7265456147755885e-07 6.762821943243494 -0.1043522305818303 NIDDGTSDRPYSHALVAGIDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NIDDGTSDRPYSHALVAGIDR 21 1 K7ELC7;P61353 K7ELC7 RPL27 60S ribosomal protein L27 0 ; 63.606 0.0024468000000000003 20989000.0 88539.0 102075.0 136499.0 118110.0 138111.0 104901.0 111693.0 95467.0 97526.0 76277.0 False True 103526.90397503902 112208.33140982642 139753.65383534032 111492.67961778636 111049.140988109 99399.80689234364 101112.63045270709 92961.09240564752 98952.13324893486 90105.41629160043 1.1489531732476967 1.2453006270643734 1.551001699865273 1.2373582433376942 1.2324358019581219 1.1031501876720105 1.122159295346741 1.0316926132920303 1.0981818554470084 1.0 16.45932620947476 -6.680313650439897 1.648442183621697 1.0638657311514867 1.311017759160553 0.535255564320255 0.1009228888324171 0.3047208744590663 1.7124026742192893 0.04388825403548916 0.04257622439926093 2.08778777166326e-07 6.680313650439897 0.24715202800906622 NIDDGTSDRPYSHALVAGIDR ddPTM_PC-9_Lapatinib_30min_R1 2 NIDDGTSDRPYSHALVAGIDR 21 1 K7ELC7;P61353 K7ELC7 RPL27 60S ribosomal protein L27 0 ; 82.609 0.00028037 41265000.0 70185.0 108287.0 111839.0 101973.0 129599.0 119862.0 131703.0 127320.0 130935.0 108525.0 False True 69184.14902964745 108036.26810463332 102644.0291310247 109472.43459195577 121976.24162143734 114735.78167196889 138521.93691227166 133235.75200451128 116187.72149332488 127283.40164952731 0.5435441552712806 0.848785204547796 0.8064211656886205 0.8600684234805906 0.9583043825093303 0.9014198252486363 1.0882953717224613 1.0467645449276541 0.9128269671268355 1.0 16.9576847717656 -4.117243954092703 0.4920577791432201 1.0081476589823957 5.4956086392921505e-14 0.779622576843487 0.06810712751521272 3.9730254226794726 0.4531128659105687 0.04170838236094243 2.6584960719428543 7.634068383643605e-05 4.117243954092703 -1.0081476589823406 NIDDGTSDRPYSHALVAGIDRYPR ddPTM_PC-9_AZD4547_30min_R2 2 NIDDGTSDRPYSHALVAGIDRYPR 24 2 K7ELC7;P61353 K7ELC7 RPL27 60S ribosomal protein L27 0 ; 64.76100000000001 0.00035371 16583700.0 34290.0 30747.0 48921.0 76727.0 61350.0 48687.0 42322.0 55419.0 40678.0 50858.0 False True 45193.50672369232 40685.36645964405 48272.27557558642 59038.775570333135 52832.61147808443 45642.59419341409 46088.57601142226 46855.26695192951 42828.15603421706 49077.47689997043 0.9208604349364902 0.8290028141130573 0.9835932616090846 1.2029708799143402 1.0765144179226593 0.9300110167937664 0.9390983180606423 0.9547203709642567 0.8726641779386761 1.0 15.582773460712705 -10.465903582761845 14.451487716806144 1.0000041894312428 0.9718887692981389 0.0077163639222628255 0.10023571405971272 0.0 0.0 0.10805918936990659 0.02620820303474977 3.420553734203074e-11 10.465903582761845 -0.028115420133103863 NIDDGTSDRPYSHALVAGIDRYPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NIDDGTSDRPYSHALVAGIDRYPR 24 2 K7ELC7;P61353 K7ELC7 RPL27 60S ribosomal protein L27 0 58.107 0.0014922000000000002 5933300.0 10931.0 6198.4 10233.0 13777.0 18444.0 17810.0 11460.0 16275.0 13135.0 10450.0 False True 12781.402402908876 6813.736188201491 10476.993528868612 13005.11935563664 14830.030601361832 16876.01224728688 10374.425836784965 15847.798494787892 13327.074526021359 12344.502277845511 1.0353922835631424 0.5519652420843244 0.8487173717543486 1.053515084117788 1.201346985692332 1.367087296631959 0.840408596740574 1.283794043541933 1.0795959388285143 1.0 13.591581048694405 -5.783654030707506 3.24123603194496 1.1388572380107136 0.7752072899758599 0.3934048466978505 0.1756320418409908 0.2141156980446021 4.644179908829776 0.04872859914252764 0.08266575452538673 1.645682190665114e-06 5.783654030707506 -0.36364994803485373 NIEDVIAQGIGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NIEDVIAQGIGK 12 0 P05387;H0YDD8 P05387 RPLP2 60S acidic ribosomal protein P2 0 149.38 0.00074194 7177500.0 35569.0 39049.0 40030.0 42401.0 45658.0 45293.0 46886.0 42091.0 39882.0 36357.0 False True 41590.129180227406 42925.526654149486 40984.46701462039 40025.40943589673 36711.64265869545 42917.75534623043 42444.61865475567 40986.15584910092 40465.198800668746 42948.23629814637 0.9683780468075338 0.999471232209881 0.9542759039068915 0.93194535761703 0.8547881315508156 0.9992902862947772 0.9882738457548156 0.9543152264641394 0.9421853442306597 1.0 15.390311266765046 NIEDVIAQGIGK ddPTM_PC-9_Lapatinib_30min_R1 2 NIEDVIAQGIGK 12 0 P05387;H0YDD8 P05387 RPLP2 60S acidic ribosomal protein P2 0 ; 174.84 0.0050027 36918000.0 270860.0 263680.0 270410.0 274010.0 289190.0 229080.0 270240.0 245940.0 259910.0 267400.0 False True 266997.4867303596 263069.46516045084 248177.93361278527 294161.60947056353 272180.4127694156 219282.78241156196 284231.7049055246 257367.2702481113 230636.1988263646 313619.7337118965 0.8513414751370015 0.8388166842910365 0.791333921100677 0.9379563141291103 0.8678676228309385 0.6991995682676135 0.9062940700237667 0.8206348089197061 0.7354007864767723 1.0 18.25865681460607 -10.791312161295261 4.462827832309834 1.0000860456174685 0.8296658453855507 0.3619158218862871 0.06860750971262432 6.270145056750007e-05 1.0278257364545086e-05 0.06592069934266652 0.015979448972558357 1.6169174152823475e-11 10.791312161295261 -0.17042020023191784 NIEDYIHR ddPTM_PC-9_AZD4547_30min_R2 1 NIEDYIHR 8 0 Q9BUQ8 Q9BUQ8 DDX23 Probable ATP-dependent RNA helicase DDX23 0 129.42 2.4719e-05 0.0 7744.9 7821.6 11052.0 13344.0 11268.0 10353.0 9790.8 12233.0 8446.5 9401.2 False True 10207.617096072458 10349.779240275542 10905.44325875149 10267.746962744855 9703.632699837895 9705.625273366933 10662.162232707173 10342.670936374774 8892.964746128486 9072.06684950258 1.1251699602094687 1.1408402750959687 1.2020902667124231 1.131797983092225 1.069616534006244 1.069836172327047 1.1752737727336937 1.1400567376707393 0.9802578501299387 1.0 13.147215555794359 -8.261047495933074 24.999877226054135 0.9901289078913086 1.1317833394838468 0.6828008940722984 0.03863384132765149 21.50379707925475 1372071.1756494853 0.033357782796939406 0.010782373971351872 5.482170067514405e-09 8.261047495933074 0.1416544315925382 NIEDYIHR ddPTM_PC-9_Lapatinib_30min_R1 1 NIEDYIHR 8 0 Q9BUQ8 Q9BUQ8 DDX23 Probable ATP-dependent RNA helicase DDX23 0 131.44 1.6458e-05 0.0 19922.0 15932.0 18242.0 17249.0 18727.0 18266.0 13867.0 15706.0 17586.0 14026.0 False True 19637.908626752636 15895.110432859155 16742.213176156343 18517.549000977207 17625.514678698582 17484.8057601257 14584.965408247888 16435.75809757194 15605.279491210224 16450.375411529778 1.1937665941039115 0.9662460603615497 1.0177404926833475 1.125661180230488 1.0714354072640293 1.0628818688156445 0.8866038034624756 0.9991114297642354 0.9486275602119547 1.0 14.00583288741102 -7.170474711009913 8.753905464248128 0.9586395638579828 1.0682477303247198 0.4346737550591988 0.06377429016472849 0.35691066144593797 31.678673548060843 0.023963796520524494 0.018553436953346946 6.753443781881268e-08 7.170474711009913 0.10960816646673699 NIELICQENEGENDPVLQR ddPTM_PC-9_Lapatinib_30min_R1 1 NIELICQENEGENDPVLQR 19 0 Q15691 Q15691 MAPRE1 Microtubule-associated protein RP/EB family member 1 0 195.6 4.2053e-14 3490900.0 9743.6 9681.5 13253.0 10577.0 10216.0 10444.0 9443.0 8601.4 8952.2 10159.0 False True 9604.6544772426 9659.083081579593 12163.389498059423 11354.867863837666 9615.114965428776 9997.334466153115 9931.912335046147 9001.052444954488 7943.908965154786 11914.96961398339 0.8060997877804567 0.810667873650614 1.0208493930009261 0.9529917600890572 0.8069777160106638 0.8390566480690189 0.8335658970871457 0.755440654619116 0.6667166784740958 1.0 13.5404876518656 -6.2873435461302885 21.565659967894785 0.8066667202697188 0.9002388124003395 0.1353777054714843 0.09776274922783244 251.3582940288709 209258.37198392273 0.031136035951489668 0.03532810085031482 5.160080226306356e-07 6.2873435461302885 0.09357209213062079 NIGNGIIS(ph)SPLTGK ddPTM_PC-9_AZD4547_30min_R2 1 NIGNGIISSPLTGK 14 0 A0A075B784;Q9P275;E9PEW0;K7EMM6 A0A075B784 USP36 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 36 1 NIGNGIIS(0.65)S(0.35)PLTGK 159.41 0.00045005 4547300.0 44864.0 35848.0 42829.0 51719.0 44839.0 46385.0 49513.0 53856.0 38350.0 47353.0 True False 59129.818770829166 47435.16495415225 42261.059476028524 39795.98360058467 38613.87882747882 43484.53861732111 53919.56108060936 45533.79268776261 40377.102706923295 45695.185883131446 1.2940054324772354 1.0380779514820428 0.9248470852950257 0.8709010113749315 0.8450316610208446 0.9516218782550919 1.1799834060969205 0.9964680481707283 0.8836183052234537 1.0 15.479754560842132 -4.785166551137483 2.915065622403119 0.957737706798559 1.3504416788649158 0.5628518244878894 0.0893161169403808 0.3289172320269526 3.9826918472879043 0.02550977082028535 0.30805590724377774 1.639960730655762e-05 4.785166551137483 0.3927039720663569 NIGNGIIS(ph)SPLTGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NIGNGIISSPLTGK 14 0 A0A075B784;Q9P275;E9PEW0;K7EMM6 A0A075B784 USP36 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 36 1 NIGNGIIS(0.468)S(0.266)PLT(0.266)GK;NIGNGIIS(0.591)S(0.405)PLT(0.004)GK 151.22 2.5660000000000003e-08 4372800.0 81062.0 92355.0 83975.0 98930.0 102684.0 89151.0 100111.0 83375.0 71960.0 72186.0 True False 94784.19555252024 101523.39404706849 85977.28247696094 93387.2728353876 82563.8073232618 84475.76461863403 90627.76133912565 81186.49459311482 73012.27886505496 85272.75037593844 1.1115414377353736 1.1905725287326434 1.0082621012916373 1.0951596192649469 0.9682320197163358 0.9906536876811083 1.0627986190146184 0.9520801690480404 0.8562205223024795 1.0 16.37979716941407 -5.520278674625267 0.48326909684901104 0.9482911046125477 1.2148341418808806 0.537617418536974 0.060950931506265016 1.9105031600611388 0.5734133529091799 0.04577615864254039 0.2697039716919798 3.018014523416157e-06 5.520278674625267 0.26654303726833284 NIGNGIISS(ph)PLTGK ddPTM_PC-9_AZD4547_30min_R2 1 NIGNGIISSPLTGK 14 0 A0A075B784;Q9P275;E9PEW0;K7EMM6 A0A075B784 USP36 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 36 1 NIGNGIIS(0.35)S(0.498)PLT(0.152)GK 154.47 0.00029612 4686200.0 49608.0 38250.0 51151.0 63660.0 53585.0 51271.0 41360.0 51948.0 46745.0 50038.0 True False 65382.31208949921 50613.56448048214 50472.70431853034 48984.17053719558 46145.64769442789 48065.016264927646 45040.959875063214 43920.63024628436 49215.84526819114 48286.18485038187 1.3540583562791488 1.0481997001277243 1.0452825062680673 1.0144551840029705 0.9556697808578876 0.9954196301459821 0.932791853707759 0.9095899869160405 1.019253134632398 1.0 15.559322858490308 -1.625119303027657 0.9393252857287391 0.9691308039648625 199.99999999702317 0.8950355016261201 0.03798208077194149 263.9187607061008 0.6019706054972553 0.012389183220929004 112643.56672764999 0.023707223660305875 1.625119303027657 199.0308691930583 NIGRDT(ph)PTSAGPNSFNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NIGRDTPTSAGPNSFNK 17 1 Q8WW12;Q8WW12-3 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 1 NIGRDT(0.439)PT(0.439)S(0.121)AGPNSFNK;NIGRDT(0.989)PT(0.004)S(0.007)AGPNSFNK 171.25 0.0001226 36154000.0 129558.0 117000.0 116782.0 131866.0 169964.0 111173.0 135871.0 112493.0 102952.0 90717.0 True False 151489.61051285992 128614.98677393742 119566.52577820157 124477.97553534008 136660.77429678306 105342.89217111864 123000.31525914572 109540.17794618566 104457.47823395113 107163.27398462298 1.4136336533969407 1.200177840706813 1.1157416280073558 1.1615730922256222 1.275257550608175 0.9830130067343262 1.147784223882477 1.0221802103760262 0.9747507177593313 1.0 16.709451037710203 -1.5228787452808974 0.23819758428060658 0.9864642937906009 3.12279945659987 0.6424767871630732 0.08071386678010206 34.34063385690095 0.45720835090813605 0.11402189490396643 28.929061639585946 0.02999999999996133 1.5228787452808974 2.136335162809269 NIGRDT(ph)PTSAGPNSFNK ddPTM_PC-9_Lapatinib_30min_R1 2 NIGRDTPTSAGPNSFNK 17 1 Q8WW12;Q8WW12-3 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 1 NIGRDT(0.999)PT(0.001)SAGPNSFNK;NIGRDT(0.99)PT(0.005)S(0.005)AGPNSFNK 143.88 0.0011829 67259000.0 74928.0 67675.0 75683.0 57726.0 60646.0 69747.0 53592.0 56241.0 64473.0 52011.0 True False 73859.5129798878 67518.30269543963 69460.63588482847 61971.36260829093 57078.9215146235 66764.08339819814 56366.73153233006 58854.162177864695 57211.37180921168 61001.03204969882 1.2107912030031378 1.106838694801607 1.1386796837836684 1.0159067892130345 0.9357041937933133 1.0944746532124905 0.9240291457103037 0.9648060073789403 0.9378754733624897 1.0 15.896546030755909 -5.304234689678314 0.6829912790476658 0.963682565674076 1.2588163380157629 0.7021041112067996 0.05132551491582591 0.9887205369661257 0.5528340100297378 0.024802732790955243 0.20415665483644568 4.963240389539483e-06 5.304234689678314 0.2951337723416869 NIGRDTPTS(ph)AGPNSFNK ddPTM_PC-9_AZD4547_30min_R2 1 NIGRDTPTSAGPNSFNK 17 1 Q8WW12;Q8WW12-3 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 1 NIGRDT(0.251)PT(0.251)S(0.493)AGPNS(0.005)FNK 152.89 0.00014556 37582000.0 31305.0 32968.0 45142.0 53980.0 50310.0 44670.0 41333.0 51332.0 45711.0 42430.0 True False 41259.338815549374 43624.26127562187 44543.387584741155 41535.74498268645 43325.32491381296 41876.77783843339 45011.55692736916 43399.818892012576 48127.19013914394 40944.538614686884 1.0076884539797835 1.0654476213824955 1.0878957021331133 1.0144391996589137 1.058146614412504 1.0227683411582542 1.0993299338638396 1.0599660018258206 1.1754239214184385 1.0 15.321383410439864 -7.271248500219522 24.691205358102255 1.0886771330731664 1.045231224088287 0.15260147081722253 0.04645902342709524 1042.1577801037026 2623277.458991985 0.01824808394064129 0.012470595040465497 5.354901661639414e-08 7.271248500219522 -0.04344590898487932 NIGRDTPTS(ph)AGPNSFNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NIGRDTPTSAGPNSFNK 17 1 Q8WW12;Q8WW12-3 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 1 NIGRDT(0.036)PT(0.323)S(0.642)AGPNSFNK 179.1 3.4070999999999994e-32 0.0 21246.0 23721.0 19036.0 23960.0 25901.0 18534.0 27072.0 18782.0 16440.0 15130.0 True False 24842.528172372342 26075.86411337242 19489.890434432014 22617.59887936807 20825.88498188422 17562.044412757707 24507.54417569307 18288.992401173964 16680.40389857565 17872.949230985898 1.3899512526619533 1.458956984455891 1.090468628459083 1.2654654017679683 1.165218158051884 0.9826047277251153 1.3712087389139413 1.0232778130129068 0.9332765221342003 1.0 14.125490093942897 -1.522878745413062 0.2291344197725339 0.9877453020650873 3.539286640547616 0.5069560129911443 0.12743299092472432 42.88118865936675 0.5601961878966221 0.18786089319303922 40.98446224423042 0.02999999999083173 1.522878745413062 2.5515413384825285 NIGVDNPAAK ddPTM_PC-9_Lapatinib_30min_R1 1 NIGVDNPAAK 10 0 P78371;P78371-2;F5GWF6;F8VQ14 P78371 CCT2 T-complex protein 1 subunit beta 0 119.68 0.0019399999999999999 0.0 35526.0 33009.0 30033.0 39639.0 34579.0 30453.0 30828.0 25344.0 30331.0 31112.0 False True 35019.39272532951 32932.5696885669 27563.802670732563 42554.18429182767 32545.13120492968 29150.59617941024 32424.122997437524 26521.574762820794 26914.803380410387 36489.667745865845 0.9597070866532373 0.9025176638474065 0.7553865072902849 1.1661981848724536 0.8918999052441888 0.7988726118974571 0.8885836731443264 0.726824232753547 0.7376006700817314 1.0 15.155200394172201 -6.538298819334881 11.016383483906507 0.8200221896413721 0.9416770419579451 0.17242431508738987 0.11831829860614713 0.7001636514555911 486.87854649068913 0.038812817100760406 0.039168342082756796 2.8953507359972204e-07 6.538298819334881 0.12165485231657303 NIHLNLDR ddPTM_PC-9_AZD4547_30min_R2 1 NIHLNLDR 8 0 Q9Y5S9;Q9Y5S9-2;A0A0J9YW13 Q9Y5S9 RBM8A RNA-binding protein 8A 0 96.66799999999999 0.0050771 2380900.0 17367.0 18658.0 21238.0 23384.0 23171.0 24060.0 20960.0 23408.0 24374.0 21804.0 False True 22889.344743959304 24688.833622923834 20956.370243337304 17993.180079198584 19954.10661057366 22555.524396523568 22825.399395099714 19790.83146232819 25662.359879492768 21040.648596621086 1.0878630779297886 1.173387479456722 0.9959944983208685 0.8551628052990774 0.9483598625271508 1.0719975809180025 1.0848239440092755 0.9405998760659117 1.219656312477643 1.0 14.360891557217037 -9.900527566412315 14.958732643399026 0.9999073662599746 1.0354077164003037 0.010754333434400132 0.10494084077724902 0.0 0.0 0.10574415914090572 0.025646725731181038 1.257397039802253e-10 9.900527566412315 0.03550035014032915 NIHLNLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NIHLNLDR 8 0 Q9Y5S9;Q9Y5S9-2;A0A0J9YW13 Q9Y5S9 RBM8A RNA-binding protein 8A 0 86.13600000000001 0.010661 2262200.0 18070.0 25218.0 20832.0 19067.0 23895.0 16807.0 22432.0 14745.0 17336.0 16408.0 False True 21128.894101231665 27721.476380044096 21328.713885799938 17998.737806048037 19212.946281692744 15925.611332967459 20307.078566383974 14357.959373618887 17589.506203510187 19382.640514343468 1.090093689020128 1.4302218709328975 1.100402902794196 0.9286009196078666 0.9912450405028589 0.8216430223313613 1.0476941235822028 0.7407638480935436 0.9074876145225759 1.0 14.24247750331865 -5.595090175779915 3.3359470474998822 0.912473956695684 1.263787245070643 0.5906649503956665 0.1140865224279261 0.14359533019659523 3.1965839998336354 0.030160517165995736 0.05844097192625366 2.54044515933759e-06 5.595090175779915 0.3513132883749591 NIHLNLDR ddPTM_PC-9_Lapatinib_30min_R1 2 NIHLNLDR 8 0 Q9Y5S9;Q9Y5S9-2;A0A0J9YW13 Q9Y5S9 RBM8A RNA-binding protein 8A 0 ; 76.1 0.020163999999999998 2923100.0 28274.0 31308.0 28382.0 30291.0 24882.0 20011.2 21348.0 22158.0 20773.0 22020.0 False True 27870.807575183426 31235.508249557774 26048.54151768829 32518.701187813786 23418.489679894177 19155.367624385595 22453.294983433767 23187.54157175595 18433.32599061242 25826.12766019433 1.07917098304058 1.2094538004511182 1.0086119708080266 1.2591396439945073 0.9067751072875307 0.7417049848285874 0.8694023075724554 0.8978326862177943 0.7137471878536249 1.0 14.656543723189724 -6.417566973283678 5.517986271401118 0.8381057965514533 1.133270424587046 0.6713231566479889 0.09802290500695993 0.127404450348497 5.537277256292508 0.028799572045523535 0.03257419806826118 3.823252900847341e-07 6.417566973283678 0.2951646280355926 NIIEATHMYDNAAEACS(ph)TTEEVFNSPR ddPTM_PC-9_AZD4547_30min_R2 1 NIIEATHMYDNAAEACSTTEEVFNSPR 27 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 NIIEATHMYDNAAEACS(0.681)T(0.108)T(0.077)EEVFNS(0.133)PR 98.00200000000001 1.6075e-09 9728200.0 17918.0 18130.0 24937.0 38527.0 30301.0 24236.0 19801.0 29704.0 24105.0 27933.0 True False 23615.55128244734 23990.167948526574 24606.319086453645 29645.195386216375 26094.229183332285 22720.519088700945 21563.250640380218 25113.92933001522 25379.14108866716 26955.074172143493 0.8761078204285798 0.8900056366129024 0.9128640837457924 1.0998001785078733 0.9680637128537067 0.842903230152536 0.7999699983264964 0.9316957975937982 0.9415348266744905 1.0 14.718269258980689 -6.739118347422165 24.993127115606832 0.8924985648565843 0.9523996884697803 0.07295085975715321 0.07730949205720418 566.0157087039894 633773.2543164989 0.02746890671025565 0.027448168807468892 1.823398749317074e-07 6.739118347422165 0.059901123613195995 NIIEATHMYDNAAEACS(ph)TTEEVFNSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NIIEATHMYDNAAEACSTTEEVFNSPR 27 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 NIIEATHMYDNAAEACS(0.817)T(0.101)T(0.02)EEVFNS(0.062)PR 147.35 9.175499999999999e-10 9177600.0 9067.0 13181.0 10948.0 12528.0 15287.0 10894.0 14905.0 12026.0 12331.0 10176.0 True False 10601.86401858703 14489.522569805737 11209.041840521213 11826.096776324013 12291.622088647699 10322.699462209055 13493.090497144838 11710.330242600265 12511.317547039924 12020.828246828318 0.8819578652065276 1.205368072173295 0.9324683466364896 0.983800494732492 1.0225270535656168 0.8587344607417287 1.1224759409323541 0.9741699991171592 1.0408032866072288 1.0 13.553248682123153 NIIEATHMYDNAAEACST(ph)TEEVFNSPR ddPTM_PC-9_Lapatinib_30min_R1 1 NIIEATHMYDNAAEACSTTEEVFNSPR 27 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 NIIEATHMYDNAAEACS(0.124)T(0.394)T(0.297)EEVFNS(0.184)PR 63.261 0.0016429000000000003 3309300.0 12463.0 12578.0 13914.0 13105.0 17505.0 14068.0 11900.0 11883.0 17849.0 10322.0 True False 12285.275334565717 12548.876413790013 12770.044629593222 14068.785416998453 16475.39031615415 13466.344434109717 12516.123772852812 12435.127561024272 15838.657661697436 12106.14394679954 1.0147967336712143 1.036570890692863 1.054839979246174 1.1621194559410282 1.3609114833389777 1.1123562129516698 1.033865434597088 1.0271749299917836 1.3083156561908094 1.0 13.563451790022043 -5.670791626361596 4.694710561534228 1.1477137202657175 1.0308567973541225 0.16854860868287136 0.11064873770010678 0.38997995334333674 14.890133179135834 0.031807533928110865 0.05612038398647198 2.1340685894607075e-06 5.670791626361596 -0.116856922911595 NIIEATHMYDNAAEACSTTEEVFNS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 NIIEATHMYDNAAEACSTTEEVFNSPR 27 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 NIIEATHMYDNAAEACST(0.005)T(0.001)EEVFNS(0.994)PR;NIIEATHMYDNAAEACSTTEEVFNS(0.999)PR;NIIEATHMYDNAAEACS(0.015)T(0.112)T(0.112)EEVFNS(0.761)PR;NIIEATHMYDNAAEACS(0.077)T(0.053)T(0.01)EEVFNS(0.859)PR 166.61 1.8463e-13 57125300.0 93215.6 103033.4 132610.9 177736.0 164620.0 134813.3 125595.8 155268.9 113788.8 141153.5 True False 122856.22179507182 136336.93162204718 130852.39281957732 136761.71119382643 141765.3545480402 126383.40303931241 136773.58288869576 131275.6592293698 119803.4436635607 136211.75892878143 0.9019501896257534 1.0009189565882575 0.9606541597336962 1.0040374800925413 1.0407717781705064 0.9278450262535132 1.0041246362599876 0.9637615743440148 0.8795381882279352 1.0 17.055491728564753 -9.781426811745723 9.463538187022603 1.0000021291187555 0.9692035170391488 0.03942137859736361 0.04789247008772443 0.0 0.0 0.045596826960077184 0.011058854926435841 1.6541435211616822e-10 9.781426811745723 -0.03079861207960677 NIIEATHMYDNAAEACSTTEEVFNS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NIIEATHMYDNAAEACSTTEEVFNSPR 27 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 NIIEATHMYDNAAEACS(0.002)T(0.004)T(0.01)EEVFNS(0.984)PR;NIIEATHMYDNAAEACS(0.287)T(0.156)T(0.023)EEVFNS(0.534)PR;NIIEATHMYDNAAEACS(0.002)T(0.016)T(0.002)EEVFNS(0.98)PR 159.89 4.8799999999999996e-11 37395800.0 114988.0 117106.0 112315.0 140546.0 156036.0 139530.0 122531.0 128495.0 119972.0 92905.0 True False 134453.19728347694 128731.50975340784 114993.01555700946 132671.66327627993 125461.865913798 132212.80117147302 110923.97663238217 125122.14240170641 121726.36353527504 109747.94106442478 1.2251090633631982 1.1729742581488543 1.0477920081389562 1.2088761027270511 1.1431819558250187 1.2046950483914847 1.0107157870712766 1.1400864671188373 1.1091448491395262 1.0 16.743834348648406 -14.522878742682927 0.08184583925033884 0.5267302105848302 1.2759104155757752 0.3988159418554629 0.060632290109708824 264.9959290996451 1.5248656344151825 22.278669184080435 1.9606815501056367 3.000000017942276e-15 14.522878742682927 0.7491802049909451 NIIEATHMYDNAAEACSTTEEVFNS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 5 NIIEATHMYDNAAEACSTTEEVFNSPR 27 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 NIIEATHMYDNAAEACST(0.001)T(0.014)EEVFNS(0.985)PR;NIIEATHMYDNAAEACS(0.008)T(0.072)T(0.01)EEVFNS(0.911)PR;NIIEATHMYDNAAEACS(0.003)T(0.019)T(0.048)EEVFNS(0.93)PR;NIIEATHMYDNAAEACS(0.387)T(0.044)T(0.026)EEVFNS(0.543)PR;NIIEATHMYDNAAEACS(0.085)T(0.004)T(0.004)EEVFNS(0.906)PR 165.23 2.2325e-13 47274500.0 142624.0 162129.0 188109.0 156736.0 171375.0 164953.0 146272.0 159394.0 179997.0 118337.0 True False 140590.155605962 161753.60026167586 172643.40414173892 168262.88829596827 161295.05943621355 157898.34471422387 153845.24844560734 166800.0271364054 159723.84240756076 138791.39277585872 1.0129601900674647 1.1654440309774827 1.2439056968075068 1.212343827168768 1.1621402178497995 1.137666692121333 1.1084638994441094 1.2018038280354981 1.1508195084223047 1.0 17.082558575605013 -6.772766390884593 4.386209132089515 1.131135887942921 1.1676649458412156 0.05155199425600154 0.07406729586227961 0.7526921175297051 34.297130427193224 0.02674289955905046 0.024770473225251104 1.6874604745078538e-07 6.772766390884593 0.03652905789829464 NIIGSS(ph)PVADFSAIK ddPTM_PC-9_AZD4547_30min_R2 2 NIIGSSPVADFSAIK 15 0 P42566;B1AUU8 P42566 EPS15 Epidermal growth factor receptor substrate 15 1 NIIGS(0.029)S(0.971)PVADFSAIK;NIIGS(0.029)S(0.97)PVADFS(0.001)AIK 260.25 2.0526999999999996e-50 67541000.0 170483.0 187782.0 208799.0 207131.0 195837.0 224880.0 201306.0 223060.0 218930.0 201150.0 True False 224693.04773331093 248478.85922284692 206030.18883315718 159380.1480920493 168648.41294268347 210818.21805029962 219221.84401860432 188591.20240887397 230502.19284554682 194107.7997252948 1.1575683617623864 1.280107546293859 1.061421483962701 0.8210909006109348 0.868838929612092 1.0860883403379653 1.129381943069013 0.9715797236163202 1.187495779004028 1.0 17.56649856466212 -5.40733829620461 5.366802876703433 1.005738484658081 1.2155151606819328 0.36735484471429547 0.1080747717042294 0.24035465787136334 9.6011266168219 0.030530224730013055 0.06499216745628958 3.914368463195618e-06 5.40733829620461 0.20977667602385175 NIIGSS(ph)PVADFSAIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NIIGSSPVADFSAIK 15 0 P42566;B1AUU8 P42566 EPS15 Epidermal growth factor receptor substrate 15 1 NIIGS(0.086)S(0.914)PVADFSAIK;NIIGS(0.11)S(0.888)PVADFS(0.002)AIK 237.06 5.245799999999999e-32 31245000.0 142724.0 142535.0 138536.0 152693.0 165378.0 140526.0 150111.0 115351.0 122147.0 118805.0 True False 166884.3542725065 156684.93281900123 141839.2236407059 144138.1062473855 132973.36807590656 133156.56917811537 135891.3993704734 112323.15847448692 123933.16879557887 140343.40604013775 1.189114323082469 1.1164395766067545 1.0106582677645741 1.0270386782985905 0.9474856840646765 0.9487910614057139 0.9682777638417077 0.8003451080727146 0.883070835263428 1.0 17.098601755624813 -4.758477620689798 0.5053366972153851 0.897074443333617 1.4022420188937086 0.743395692028664 0.05286342921753643 2.2481156195644587 0.43383783829847367 0.03374868944690015 0.6823506016488234 1.7439032189473838e-05 4.758477620689798 0.5051675755600916 NIIGSS(ph)PVADFSAIK ddPTM_PC-9_Lapatinib_30min_R1 2 NIIGSSPVADFSAIK 15 0 P42566;B1AUU8 P42566 EPS15 Epidermal growth factor receptor substrate 15 1 NIIGS(0.13)S(0.835)PVADFS(0.035)AIK;NIIGS(0.098)S(0.655)PVADFS(0.247)AIK 108.06 0.00077374 30729000.0 104877.0 115043.0 124933.0 128802.0 150612.0 145360.0 138393.0 133595.0 148643.0 120908.0 True False 103381.43474791375 114776.62500172065 114661.49099532606 138274.5287508763 141753.2982745849 139143.29165071005 145558.3123778504 139802.31141252565 131901.2600598181 141806.78670021708 0.7290302329920539 0.8093873902125797 0.8085754826228676 0.9750910514825497 0.9996228077169166 0.9812174359811302 1.026455191355292 0.9858647436111154 0.9301477251484479 1.0 17.113567054295252 -5.72501692234101 3.231726173653728 0.9890862238316923 0.7755770594883313 0.910868439995139 0.029283727247399766 0.06532849871650585 1.3966221230554292 0.008530117115175338 0.015171399816396525 1.8835756942878116e-06 5.72501692234101 -0.21350916434336098 NIIHGS(ph)DSVESAEK ddPTM_PC-9_AZD4547_30min_R2 1 NIIHGSDSVESAEK 14 0 P15531;P15531-2 P15531 NME1 Nucleoside diphosphate kinase A 1 NIIHGS(0.805)DS(0.195)VESAEK 62.589 0.027032 8748400.0 49443.0 48605.0 66740.0 63800.0 60059.0 77342.0 72665.0 78576.0 77420.0 72475.0 True False 65164.845521712414 64315.61572742055 65854.9839928587 49091.89570017403 51720.84454380226 72505.79251354624 79132.04422924232 66433.88469685162 81512.26314393742 69937.67230967319 0.9317559960127435 0.9196133300325031 0.9416239033701754 0.7019377980268304 0.7395276799432267 1.0367201269224662 1.131465226335499 0.9499012835699286 1.1654986569043038 1.0 16.093782160097888 -6.860497746462712 7.321162051701838 1.0607208664782495 0.8486052780267661 0.5615818071007086 0.09282057979718202 0.1860064293165203 12.017133653958757 0.03467512855437821 0.030609660792079142 1.378803107506352e-07 6.860497746462712 -0.21211558845148337 NIIHGS(ph)DSVESAEK ddPTM_PC-9_Lapatinib_30min_R1 1 NIIHGSDSVESAEK 14 0 P15531;P15531-2 P15531 NME1 Nucleoside diphosphate kinase A 1 NIIHGS(0.927)DS(0.072)VESAEK 79.332 0.00731 16056000.0 52392.0 68458.0 87260.0 71682.0 90610.0 80665.0 75548.0 85414.0 76456.0 63683.0 True False 51644.88047248392 68299.48970704697 80085.81963334062 76953.73340414219 85280.49794611409 77215.14598929917 79459.50578079699 89382.64625913708 67844.72016262752 74690.52169773637 0.6914515965156139 0.9144331590485719 1.0722353762293746 1.030301190230867 1.1417847406560377 1.033801133452778 1.0638499233190541 1.1967066801442086 0.908344440773717 1.0 16.18863755472894 -4.819441155807693 1.881637892142377 1.0661632328808068 0.5900404674008745 0.6957740652062754 0.07416399401838207 0.3785907344490654 1.5158386028640756 0.018958767481446676 0.3129568915240493 1.5155101319541581e-05 4.819441155807693 -0.4761227654799324 NIIHGS(ph)DSVK ddPTM_PC-9_AZD4547_30min_R2 7 NIIHGSDSVK 10 0 Q32Q12;P22392-2;P22392;O60361 Q32Q12 NME1-NME2;NME2;NME2P1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Putative nucleoside diphosphate kinase 1 NIIHGS(0.998)DS(0.002)VK;NIIHGS(0.872)DS(0.128)VK;NIIHGS(0.98)DS(0.02)VK;NIIHGS(0.614)DS(0.386)VK;NIIHGS(0.937)DS(0.063)VK;NIIHGS(0.764)DS(0.236)VK;NIIHGS(0.972)DS(0.028)VK 121.24 0.00036217 59762300.0 374272.2 313443.4 507533.0 719810.0 569496.0 544539.0 495077.0 605023.0 474279.0 581064.0 True False 493282.97425462515 414757.84933023655 500802.78080382856 553868.9254536409 490431.31061651406 510488.89024765394 539137.8939087683 511530.59739542956 499348.4196802318 560721.126222118 0.8797296038730336 0.7396865035649448 0.8931405602246667 0.9877796636366385 0.8746438963711167 0.9104149395744978 0.9615080807481472 0.9122727385748568 0.8905468268060677 1.0 19.09692390151178 -5.482024911774355 8.990128406290856 0.9289028948907405 0.8110519112206955 0.4951784104827699 0.049425532002742606 0.3183450470358246 66.77450498611893 0.012192825463293097 0.025071680115174567 3.295908058187097e-06 5.482024911774355 -0.11785098367004498 NIIHGS(ph)DSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NIIHGSDSVK 10 0 Q32Q12;P22392-2;P22392;O60361 Q32Q12 NME1-NME2;NME2;NME2P1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Putative nucleoside diphosphate kinase 1 NIIHGS(0.968)DS(0.032)VK;NIIHGS(0.939)DS(0.061)VK;NIIHGS(0.759)DS(0.241)VK 78.486 0.011522 21360500.0 175569.0 164805.0 143076.0 219627.0 215432.0 185060.0 205466.0 199190.0 178663.0 149591.0 True False 205289.3640541858 181165.751241699 146487.47445875136 207322.01123034136 173219.64609155201 175355.1278204888 186002.77303497915 193961.47355925044 181275.60837781164 176710.66413829543 1.1617259493378647 1.0252111955162875 0.828967935653894 1.1732286347364367 0.980244440459964 0.9923290633057337 1.0525837472344717 1.0976217791103675 1.0258328735380886 1.0 17.43102958073944 -7.364766637506967 24.983362305825025 1.0521452868276402 1.022397150957885 0.003511161426216547 0.09367291615053497 197.83690994405717 47777.91014155067 0.039135308878152184 0.026385020520224504 4.317510103006053e-08 7.364766637506967 -0.02974813586975511 NIIHGS(ph)DSVK ddPTM_PC-9_Lapatinib_30min_R1 4 NIIHGSDSVK 10 0 Q32Q12;P22392-2;P22392;O60361 Q32Q12 NME1-NME2;NME2;NME2P1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Putative nucleoside diphosphate kinase 1 NIIHGS(0.971)DS(0.029)VK;NIIHGS(0.896)DS(0.104)VK;NIIHGS(0.79)DS(0.21)VK;NIIHGS(0.916)DS(0.084)VK 118.24 0.00073382 48463400.0 365011.0 315727.0 378012.0 349022.0 328582.0 385259.0 357723.0 367393.0 350976.0 276475.0 True False 359805.87620518013 314995.95352970966 346933.31252851686 374690.2421832606 309255.45277706697 368782.3706525931 376244.1465879179 384463.4200140862 311445.38693887135 324263.3353702187 1.1096101130100995 0.9714201982474268 1.0699122431847417 1.1555122066312815 0.9537169918516477 1.13729284327365 1.1603043130311095 1.1856518393457458 0.9604705588539241 1.0 18.306806381147794 NIIHGSDS(ph)VK ddPTM_PC-9_AZD4547_30min_R2 2 NIIHGSDSVK 10 0 Q32Q12;P22392-2;P22392;O60361 Q32Q12 NME1-NME2;NME2;NME2P1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Putative nucleoside diphosphate kinase 1 NIIHGS(0.087)DS(0.913)VK;NIIHGS(0.055)DS(0.945)VK 95.477 0.005901600000000001 9836000.0 41277.0 32240.0 86046.0 118767.0 92262.0 96185.0 59922.0 100612.0 73730.0 109246.0 True False 54402.227385064085 42660.949512437764 84904.97381854233 91387.10308185847 79453.0138580444 90170.53674478894 65254.941915704454 85064.72723375626 77627.21727722167 105421.33079189465 0.5160457279035489 0.40467094459898206 0.8053870424586812 0.8668748762265178 0.753671133358081 0.8553348365786493 0.6189918247619162 0.8069024228282317 0.7363520901710155 1.0 16.685807283671046 -5.266096926638386 24.91456438584688 0.7940113583804411 0.4603583227858726 0.6693981213242746 0.09673805480060908 188.2022508587484 1006753.7345494453 0.023966795007741504 0.052664073508883545 5.418799391471635e-06 5.266096926638386 -0.33365303559456855 NIIHGSDS(ph)VK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NIIHGSDSVK 10 0 Q32Q12;P22392-2;P22392;O60361 Q32Q12 NME1-NME2;NME2;NME2P1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Putative nucleoside diphosphate kinase 1 NIIHGS(0.008)DS(0.992)VK 89.266 0.009459 4266300.0 17372.0 19715.0 15867.0 27037.0 27019.0 24348.0 27610.0 25081.0 20586.0 17952.0 True False 20312.736487360093 21672.174908104105 16245.329455932591 25522.204545136672 21724.82090751438 23071.14801779567 24994.58092091038 24422.65032551613 20887.03130511426 21206.5554920462 0.9578517593287913 1.0219563906185776 0.7660522455910211 1.2035054233446405 1.0244389248250412 1.0879252892554292 1.1786252100339882 1.151655691310933 0.984932763500806 1.0 14.372222687447591 -5.772710453210232 24.999971372802406 1.097328946536265 0.9259537250719915 0.43014247087692126 0.09172988498851005 194.9780966466128 432474.0606450168 0.02515711570777494 0.037690530321647465 1.6876778355328224e-06 5.772710453210232 -0.17137522146427353 NIIHGSDS(ph)VK ddPTM_PC-9_Lapatinib_30min_R1 4 NIIHGSDSVK 10 0 Q32Q12;P22392-2;P22392;O60361 Q32Q12 NME1-NME2;NME2;NME2P1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Putative nucleoside diphosphate kinase 1 NIIHGS(0.138)DS(0.862)VK;NIIHGS(0.013)DS(0.987)VK;NIIHGS(0.01)DS(0.99)VK;NIIHGS(0.005)DS(0.995)VK 106.54 0.0013040999999999999 15977000.0 156699.0 111262.0 238123.0 144280.0 198320.0 232188.0 154135.0 185367.0 235989.0 141316.0 True False 154464.44352492318 111004.37967491678 218545.44612136207 154890.832503971 186655.20751212176 222257.86049666404 162115.35611165268 193979.82753550305 209409.43374566163 165742.28230826592 0.9319555720708191 0.6697408659334043 1.3185859581376282 0.9345281743851447 1.1261773695438781 1.3409846745279166 0.9781170734099855 1.1703701966328532 1.263464161523845 1.0 17.33858216809402 -5.256657080320181 24.998860717998 1.14095929750499 0.8008482112823484 0.46807221076725924 0.14526926350618707 325.7564407478723 1702836.0703231492 0.03560753187008713 0.0880534098845482 5.537872079706363e-06 5.256657080320181 -0.34011108622264163 NIILEEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NIILEEGK 8 0 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 0 104.2 0.017794 4084800.0 38652.0 46294.0 40413.0 46175.0 50975.0 34639.0 42499.0 34499.0 38733.0 36183.0 False True 45195.020188201794 50889.76237361252 41376.599187155975 43587.964451369815 40986.8146770993 32822.46986152556 38473.1870538852 33593.43780471197 39299.396849363184 42742.69147552958 1.0573742230078371 1.1906073440121845 0.9680391608199099 1.0197758481429313 0.9589198354662449 0.7679083541174894 0.9001114746344719 0.7859457756408342 0.9194413241819902 1.0 15.383390135842506 -5.953256655890753 1.1503628983875127 0.86535946195165 1.115199888367181 0.5448945996831083 0.0798855078523492 0.343303071752837 0.9195772621349045 0.02941699291747646 0.061812596627888364 1.1136362112355471e-06 5.953256655890753 0.24984042641553095 NIILEEGK ddPTM_PC-9_Lapatinib_30min_R1 2 NIILEEGK 8 0 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 0 ; 105.52 0.017696 33826100.0 185324.0 164188.0 150803.0 169151.0 152159.0 115242.0 170619.0 143599.0 128472.0 161452.0 False True 182681.24577574103 163807.83277368027 138404.5594564142 181590.92881119493 143209.30677610385 110313.36830222288 179452.8169748215 150271.1337739227 114002.13048986462 189358.76307873303 0.964736159053724 0.8650660265750205 0.7309118268736646 0.9589782160527298 0.7562856054174751 0.5825627845718233 0.9476868884077324 0.7935789784993569 0.6020430670138247 1.0 17.530762661741505 -1.5228824697897345 0.8085044546619057 0.784491934909051 49.653361260112085 0.12273800025227344 0.13494324057408782 1074.3788882341803 3.605658139282944 0.047163444996568576 96238.68006723194 0.029999742721108728 1.5228824697897345 48.868869325203036 NIIS(ph)PPWDFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NIISPPWDFR 10 0 Q5T8C6;Q13042-4;Q13042-3;Q13042-2;Q13042 Q5T8C6 CDC16 Cell division cycle protein 16 homolog 1 NIIS(1)PPWDFR;NIIS(1)PPWDFR 88.803 0.009755 5998800.0 15675.2 19126.4 19392.8 16618.9 18603.3 15076.3 15864.599999999999 12781.3 14822.6 13478.400000000001 True False 18328.70176068771 21025.142590025975 19855.197899603554 15687.796912200767 14958.116909906455 14285.672287690679 14361.790238242478 12445.804417906755 15039.352483395822 15921.927225044314 1.1511610059275783 1.3205149284286757 1.2470348356053544 0.985295102186168 0.9394664790565154 0.897232607948371 0.9020133075129356 0.7816770069348258 0.9445685984382437 1.0 13.958727352977153 -5.854337762519588 3.0213897249501636 0.9013291894670983 1.2527106140767599 0.8338376460787646 0.06554249955642685 0.09018996033205383 1.6512731890997587 0.01922936592035658 0.0314052248330433 1.3984992489702886e-06 5.854337762519588 0.3513814246096616 NIIS(ph)PPWDFR ddPTM_PC-9_Lapatinib_30min_R1 1 NIISPPWDFR 10 0 Q5T8C6;Q13042-4;Q13042-3;Q13042-2;Q13042 Q5T8C6 CDC16 Cell division cycle protein 16 homolog 1 NIIS(1)PPWDFR 90.913 0.02093 0.0 5367.6 7876.1 7755.7 5128.8 6524.1 5693.1 5358.7 5727.6 5976.5 4309.0 True False 5291.057039702718 7857.863374356144 7118.05628386777 5505.989061175251 6140.365264874113 5449.619384264293 5636.147265679528 5993.7252056317975 5303.363634664953 5053.804908618412 1.046945249247693 1.5548410586558028 1.408454899343092 1.0894740024067242 1.2149984765741066 1.078320094028736 1.1152284996336184 1.1859827029354675 1.049380364014638 1.0 12.303154257848377 -5.7647394033401245 24.999967219446173 1.1164450701383697 1.3585564913718216 0.39017330871818756 0.13149407034501442 78.54689099844398 595054.0113777969 0.03516433606168722 0.05467493896644138 1.7189395205194982e-06 5.7647394033401245 0.24211142123345186 NILY(ph)LDK ddPTM_PC-9_AZD4547_30min_R2 1 NILYLDK 7 0 C9JQI7-2;C9JQI7 C9JQI7-2 TMEM232 Transmembrane protein 232 1 NILY(1)LDK 82.305 0.032876 5903000.0 45153.0 62304.0 48667.0 69287.0 52808.0 53198.0 59134.0 76554.0 64054.0 52404.0 True False 59510.7147592557 82442.54957887491 48021.64378154707 53313.95262347893 45476.52073243166 49871.5206503018 64396.81144226274 64724.33833591382 67439.76367116735 50569.35191053621 1.1768138706728521 1.6302868528892076 0.949619521849986 1.0542739942129036 0.8992901631977718 0.986200510113933 1.2734355693580792 1.279912355816219 1.3336094120897004 1.0 15.625975668763177 -5.270307063113391 24.97431439380953 1.1007906155419442 1.403550372184824 0.3279350746224208 0.175448847400812 690.1699028955157 1943749.3611479267 0.048574322660198586 0.10365333701021796 5.36652228174733e-06 5.270307063113391 0.3027597566428797 NINHQGS(ph)LSK ddPTM_PC-9_Lapatinib_30min_R1 1 NINHQGSLSK 10 0 C9J3Z9;E9PEA7;Q99469 C9J3Z9 STAC SH3 and cysteine-rich domain-containing protein 1 NINHQGS(0.637)LS(0.363)K 65.241 0.045281999999999996 0.0 58596.0 45554.0 63037.0 45985.0 46736.0 43625.0 45214.0 44075.0 48929.0 33895.0 True False 57760.41029480966 45448.52251182943 57854.34118985681 49366.890301463056 43987.08036651132 41759.26044484197 47554.95968619892 46122.885403698165 43418.10077478815 39753.705587751465 1.452956634880504 1.1432524802375303 1.4553194559976401 1.241818581980783 1.1064900671816669 1.0504495072204902 1.1962396708208027 1.1602160030563065 1.0921774494442533 1.0 15.278801725076084 -1.522878745444444 0.17917676476724245 1.0015054559509406 2.6614347303584527 0.5455758635551397 0.0994065267926751 48.019031303008944 0.539362500853223 0.2346585291515855 21.670315548630203 0.029999999988663935 1.522878745444444 1.659929274407512 NINLSS(ph)S(ph)KLEPS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 NINLSSSKLEPSK 13 1 Q8N841-2;Q8N841 Q8N841-2 TTLL6 Tubulin polyglutamylase TTLL6 3 NINLS(0.425)S(0.575)S(1)KLEPS(1)K 89.13600000000001 0.032217 0.0 4009.0 4510.8 6889.9 3874.6 5120.8 6819.8 6549.7 7056.3 6629.8 6122.6 True False 3951.830924839441 4500.355519742726 6323.439017783113 4159.5510092867 4819.6046118801605 6528.133051730272 6888.8114180717685 7384.161458289623 5883.082109110965 7180.883252148316 0.5503265804603028 0.6267133668266153 0.8805934863084314 0.5792533958886298 0.671171559632065 0.9090988980745843 0.9593264750559525 1.028308245518473 0.8192699842809607 1.0 12.809945591819536 -6.7980706611357045 4.3547773648591495 0.9509244427360339 0.66570143796565 0.6784437400440753 0.0972158313324086 0.12872807388088822 5.372953158960327 0.03512581599630455 0.031918980236852926 1.5919496905460687e-07 6.7980706611357045 -0.285223004770384 NINMDNDLEVLTS(ph)SPTR ddPTM_PC-9_AZD4547_30min_R2 4 NINMDNDLEVLTSSPTR 17 0 Q9Y5T5-4;Q9Y5T5-3;Q9Y5T5-2;Q9Y5T5 Q9Y5T5-4 USP16 Ubiquitin carboxyl-terminal hydrolase 16 1 NINMDNDLEVLT(0.002)S(0.494)S(0.494)PT(0.01)R;NINMDNDLEVLT(0.143)S(0.425)S(0.425)PT(0.007)R;NINMDNDLEVLT(0.127)S(0.484)S(0.383)PT(0.006)R;NINMDNDLEVLT(0.016)S(0.468)S(0.468)PT(0.049)R 164.58 2.4962e-05 26967200.0 79867.2 79705.59999999999 107054.0 152323.0 120169.0 112606.0 96469.9 124357.0 98632.20000000001 114929.0 True False 105263.30825904007 105468.87647203964 105634.39401215895 117207.28571689033 103485.60861792858 105564.72901890837 105055.53421304048 105140.48308957377 103845.6967303729 110905.37069166511 0.949127238857432 0.9509807849185248 0.9524732062421005 1.0568224513017097 0.9330982618112816 0.9518450581838405 0.9472538034709957 0.9480197616568212 0.9363450668144896 1.0 16.75896970542444 NINMDNDLEVLTS(ph)SPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NINMDNDLEVLTSSPTR 17 0 Q9Y5T5-4;Q9Y5T5-3;Q9Y5T5-2;Q9Y5T5 Q9Y5T5-4 USP16 Ubiquitin carboxyl-terminal hydrolase 16 1 NINMDNDLEVLT(0.023)S(0.485)S(0.485)PT(0.006)R;NINMDNDLEVLT(0.072)S(0.461)S(0.461)PT(0.005)R;NINMDNDLEVLT(0.016)S(0.487)S(0.487)PT(0.01)R 132.5 2.3893000000000003e-05 12922500.0 54815.0 58746.0 63219.0 56453.0 54972.0 59856.0 60660.0 57218.0 51019.0 42566.6 True False 64094.09685440037 64577.91464121145 64726.3807193926 53290.12143309543 44200.63121980386 56717.04598953416 54913.845659631384 55716.088127482246 51765.05635653472 50283.58762297981 1.274652424066677 1.284274207429445 1.2872267827169193 1.0597915533127478 0.8790270008420001 1.1279435034507013 1.0920828893787111 1.108037249554162 1.0294622719576572 1.0 15.6177999660866 -5.7727683250437485 6.974980490498366 1.0451078843229966 1.2829933776126288 0.7368408895782095 0.06565740162756968 0.07463397497231443 17.462957870517812 0.019309511130220853 0.030371745958852083 1.6874529593079273e-06 5.7727683250437485 0.23788549328963216 NINMDNDLEVLTS(ph)SPTR ddPTM_PC-9_Lapatinib_30min_R1 2 NINMDNDLEVLTSSPTR 17 0 Q9Y5T5-4;Q9Y5T5-3;Q9Y5T5-2;Q9Y5T5 Q9Y5T5-4 USP16 Ubiquitin carboxyl-terminal hydrolase 16 1 NINMDNDLEVLT(0.031)S(0.605)S(0.361)PT(0.004)R;NINMDNDLEVLT(0.012)S(0.647)S(0.339)PT(0.001)R 118.15 0.00011646 24190000.0 77234.0 61130.0 85651.0 64772.0 64249.0 66811.0 73369.0 58363.0 72933.0 47482.0 True False 76132.62899701898 60988.45724081597 78609.10540242103 69535.54895305775 60470.000138394025 63953.64927404777 77167.68782272596 61074.75804460658 64718.51752146223 55689.20043421193 1.3670986188239094 1.0951577103870307 1.411568217706508 1.2486361522680345 1.0858478783481522 1.148403079509087 1.3856849662240616 1.0967073969172323 1.1621376679292967 1.0 15.765109958629369 -14.522878475005687 0.1078290439794006 0.26141387989929804 1.3554192660277324 0.31212227303505413 0.11381464547421384 224.19245378108042 1.6095535565920216 36.27928798663685 1.5251298183826292 3.000001866991727e-15 14.522878475005687 1.0940053861284345 NINMDNDLEVLTSS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 5 NINMDNDLEVLTSSPTR 17 0 Q9Y5T5-4;Q9Y5T5-3;Q9Y5T5-2;Q9Y5T5 Q9Y5T5-4 USP16 Ubiquitin carboxyl-terminal hydrolase 16 1 NINMDNDLEVLT(0.004)S(0.379)S(0.618)PTR;NINMDNDLEVLT(0.007)S(0.074)S(0.781)PT(0.139)R;NINMDNDLEVLT(0.003)S(0.121)S(0.872)PT(0.004)R;NINMDNDLEVLT(0.027)S(0.086)S(0.876)PT(0.011)R;NINMDNDLEVLT(0.123)S(0.184)S(0.693)PTR 220.1 9.576200000000001e-23 51663700.0 97879.0 86675.2 126347.0 183729.0 136187.0 130336.0 112571.0 136888.0 112767.0 120389.0 True False 129002.48599032588 114691.26337408338 124671.55622633676 141373.11763475343 117279.78580873497 122186.06931609704 122589.60092107662 115735.10497330735 118727.63340160673 116174.21775355974 1.1104226779816044 0.9872350818610878 1.073143065966688 1.2169061291606722 1.0095164665323633 1.0517485865520544 1.05522209050829 0.9962202217605296 1.0219791938127232 1.0 16.82593040508825 -7.259779492646227 1.1429473503672098 1.0066351161700404 1.0816406167032826 0.22595914279133555 0.0582130582298091 0.853882990894682 2.171969954794525 0.04142653824491584 0.023609613767615348 5.498199669093818e-08 7.259779492646227 0.07500550053324218 NINMDNDLEVLTSS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NINMDNDLEVLTSSPTR 17 0 Q9Y5T5-4;Q9Y5T5-3;Q9Y5T5-2;Q9Y5T5 Q9Y5T5-4 USP16 Ubiquitin carboxyl-terminal hydrolase 16 1 NINMDNDLEVLT(0.014)S(0.241)S(0.741)PT(0.004)R;NINMDNDLEVLTS(0.101)S(0.894)PT(0.005)R 162.37 2.7223000000000003e-05 26640900.0 88691.0 81343.0 90090.0 105344.0 123120.0 113471.0 108745.0 97691.0 89835.0 79432.0 True False 103704.6345729019 89418.19546284089 92238.08726822762 99441.9172098562 98995.51982431494 107520.3810057208 98443.88635437883 95126.71476217065 91148.66692387739 93832.39281663392 1.1052114462812452 0.9529565726580244 0.9830090067987303 1.0597823867092928 1.0550249956619004 1.1458770023677833 1.049146072047386 1.0137939778224145 0.9713987268980657 1.0 16.51779843542885 -7.951971316248325 3.6854420949474695 0.9867318108931594 1.0478591859835813 0.20332734640983152 0.05171766256090344 0.4185612340630988 11.636232689717804 0.036554863129259596 0.015093949678117112 1.1169370154367124e-08 7.951971316248325 0.061127375090421876 NINMDNDLEVLTSS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 4 NINMDNDLEVLTSSPTR 17 0 Q9Y5T5-4;Q9Y5T5-3;Q9Y5T5-2;Q9Y5T5 Q9Y5T5-4 USP16 Ubiquitin carboxyl-terminal hydrolase 16 1 NINMDNDLEVLTS(0.021)S(0.978)PTR;NINMDNDLEVLTS(0.235)S(0.757)PT(0.008)R;NINMDNDLEVLT(0.001)S(0.223)S(0.775)PT(0.002)R;NINMDNDLEVLT(0.064)S(0.258)S(0.571)PT(0.107)R 162.81 2.3945999999999997e-05 22037800.0 84777.0 79023.0 80424.0 76030.0 86336.0 81303.0 68967.1 66473.0 87975.0 62836.0 True False 83568.06443380211 78840.02709865876 73811.84916561768 81621.49982864488 81257.88622310675 77825.86021654986 72537.87897938807 69561.57825161729 78066.32908218012 73697.118876293 1.1339393684314627 1.0697843864289807 1.001556781202224 1.1075263330938845 1.1025924413613124 1.056023103795785 0.9842702141605996 0.943884636363905 1.0592860382129894 1.0 16.169320599085097 -7.144909330262189 4.056626173351804 0.9923714020324385 1.079120800461336 0.4834447433806831 0.0418423331846879 0.21194358931307208 5.979760023865414 0.017015804624352798 0.012952759904216609 7.162929385089193e-08 7.144909330262189 0.0867493984288975 NINMDNDLEVLTSSPT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 NINMDNDLEVLTSSPTR 17 0 Q9Y5T5-4;Q9Y5T5-3;Q9Y5T5-2;Q9Y5T5 Q9Y5T5-4 USP16 Ubiquitin carboxyl-terminal hydrolase 16 1 NINMDNDLEVLTS(0.001)S(0.099)PT(0.899)R 231.38 2.6937e-29 7658400.0 12448.0 14557.0 15850.0 26532.0 19792.0 20783.0 16779.0 22846.0 17430.0 16272.0 True False 16406.205065515373 19262.265572349766 15639.818643793986 20415.457315313753 17044.22243478805 19483.43572456148 18272.298494769948 19315.675648852946 18351.314215949744 15702.32223281133 1.0448266710024088 1.2267144494143443 0.99601946845246 1.3001552899388302 1.08545870999722 1.240799636874678 1.1636685468464298 1.2301158620023227 1.1687006510160085 1.0 13.938690316119265 -4.740839594021161 24.59151941955397 1.1640973491845212 1.0448261423718437 0.10317563866926482 0.09698344168670964 2701.5888711312923 3224885.3674205136 0.022006129879416438 0.9257987910572985 1.8161863444568453e-05 4.740839594021161 -0.11927120681267755 NINPS(ph)TANSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NINPSTANSPK 11 0 P46937-6;P46937-7;P46937;P46937-9;H0YCI3;P46937-4 P46937-6 YAP1 Transcriptional coactivator YAP1 1 NINPS(0.415)T(0.195)ANS(0.39)PK 106.26 0.0024564 18488000.0 54218.0 48636.0 31589.0 52431.0 51181.0 47352.0 53294.0 47494.0 39887.0 42625.0 True False 63396.03654568784 53464.26065587375 32342.201561949623 49493.46105359549 41152.45045588266 44868.777761568104 48245.6065048532 46247.33282405262 40470.271916209655 50352.575080685674 1.2590425900582272 1.0617979432075098 0.6423147477586603 0.98293803195341 0.8172859161609788 0.8910920184254677 0.9581556936769124 0.9184700633472119 0.8037378793708072 1.0 15.619777940525058 -5.002303709456951 5.882568901346116 0.8767852729622002 1.2193334847850048 0.5922368739585466 0.10037226732295648 0.08788754839862037 12.641443019381718 0.02409466909472647 0.08309263119969308 9.947095568943345e-06 5.002303709456951 0.3425482118228046 NINPST(ph)ANSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NINPSTANSPK 11 0 P46937-6;P46937-7;P46937;P46937-9;H0YCI3;P46937-4 P46937-6 YAP1 Transcriptional coactivator YAP1 1 NINPS(0.14)T(0.551)ANS(0.309)PK 102.62 0.0079298 3725200.0 25298.0 24261.0 17399.0 21839.0 22651.0 17267.0 26850.0 22064.0 17519.0 19384.0 True False 29580.451741724333 26669.471744636743 17813.85814607495 20615.43163299329 18212.699151564022 16361.488123183737 24306.57362283389 21484.843378740417 17775.182232308205 22898.16575634042 1.2918262561503913 1.1646990430773725 0.7779600486620792 0.9003093021669194 0.7953780816055536 0.7145326965175497 1.0615074535436748 0.9382779217934233 0.7762710088421088 1.0 14.482944416290144 -5.1173241309773 4.13642358451523 0.8685823597731612 1.2672055340510286 0.6601057865064199 0.10412560721407818 0.12980890283326696 3.6571629362302507 0.027350941969498565 0.08458680950606613 7.632659157070695e-06 5.1173241309773 0.3986231742778674 NINPSTANS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 NINPSTANSPK 11 0 P46937-6;P46937-7;P46937;P46937-9;H0YCI3;P46937-4 P46937-6 YAP1 Transcriptional coactivator YAP1 1 NINPS(0.001)T(0.005)ANS(0.994)PK 125.97 0.00043404 26556000.0 46338.0 44207.0 39644.0 47384.0 52797.0 48473.0 51837.0 38975.0 43220.0 48502.0 True False 61072.520109724515 58496.048234998016 39118.29465707057 36460.35087550227 45467.04789255782 45441.975647243846 56450.39257842485 32952.30930640126 45504.52096462124 46803.959742859806 1.3048579745230093 1.2498098143057628 0.8357902808220895 0.7790014151754434 0.9714359242754895 0.97090023786238 1.206102921388754 0.7040496036540649 0.9722365632015397 1.0 15.514342970463368 -5.21200612177121 7.024166905290965 0.9269046753433999 1.2817456466532897 0.5311259424696216 0.13057683716670027 0.19563970144245155 23.2053841575858 0.03400843752425982 0.09060905082372389 6.137533536984547e-06 5.21200612177121 0.3548409713098898 NINPSTANS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NINPSTANSPK 11 0 P46937-6;P46937-7;P46937;P46937-9;H0YCI3;P46937-4 P46937-6 YAP1 Transcriptional coactivator YAP1 1 NINPSTANS(0.999)PK;NINPS(0.006)T(0.019)ANS(0.975)PK 148.85 7.8018e-05 20667800.0 87313.0 84014.0 58998.0 85214.0 89690.0 73021.0 95388.0 77086.0 64270.0 67406.0 True False 102093.36638964243 92354.354690817 60404.736071161 80439.73584751548 72115.8883450521 69191.65021387614 86352.15809068464 75062.57417936818 65209.82716310562 79626.17421439773 1.2821583781577974 1.1598492028782892 0.758604022698843 1.0102172638726454 0.90568068925271 0.8689561051567531 1.0844695094627657 0.9426871869701813 0.8189496457223309 1.0 16.28095512190486 -5.065193297408396 5.618700120234582 0.9283221025817052 1.2560143398283172 0.6423957280549623 0.09068579327483862 0.11088365699098694 6.831462107605157 0.022635503716912486 0.06512226365140593 8.606106231415117e-06 5.065193297408396 0.327692237246612 NINPSTANS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 NINPSTANSPK 11 0 P46937-6;P46937-7;P46937;P46937-9;H0YCI3;P46937-4 P46937-6 YAP1 Transcriptional coactivator YAP1 1 NINPS(0.148)T(0.074)ANS(0.777)PK 100.43 0.0041525 26669000.0 84007.0 75572.0 64107.0 67067.0 62379.0 69444.0 72258.0 59082.0 51555.0 57141.0 True False 82809.04477500306 75397.0176771299 58836.36992017623 71999.33090895356 58709.98986183258 66474.04200187058 75999.16567889068 61827.16540944511 45748.33300178225 67017.74571440344 1.235628621826439 1.1250306448449456 0.8779222472046105 1.0743323300634309 0.8760364771448086 0.991887167992044 1.134015548699021 0.922549165901849 0.6826301379449418 1.0 16.03225553876643 -5.057316876701291 3.836460473640606 0.9531624333343753 1.2206534092731902 0.4036374250900453 0.11738570884374176 0.22169598680277472 6.425366242817501 0.03084961373695376 0.1085686752174307 8.763611635375885e-06 5.057316876701291 0.2674909759388149 NINTFVET(ph)PVQK ddPTM_PC-9_AZD4547_30min_R2 2 NINTFVETPVQK 12 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 NINT(0.002)FVET(0.998)PVQK;NINTFVET(1)PVQK 165.89 0.00019331 26868000.0 97428.0 100990.0 96855.0 101751.0 105293.0 123096.0 92945.0 111278.0 109178.0 100278.0 True False 128408.07737170906 133633.0425329124 95570.63941606712 78293.8789872792 90674.88443947761 115398.78766061788 101216.92494167663 94082.54201405306 114948.92618869554 96767.29774224774 1.3269780222006473 1.3809731763809439 0.9876336494445874 0.8090944029027772 0.9370405762595742 1.1925391155181115 1.0459827576386502 0.9722555471648503 1.187890215709825 1.0 16.562231954360655 -5.261640965726825 24.999989902973947 1.012650750763983 1.353975626703832 0.6124232174986739 0.10733462617925192 11.585699694586108 1437054.1523578502 0.02979860412512344 0.06898929054291364 5.474683717796416e-06 5.261640965726825 0.34132487593984906 NINTFVET(ph)PVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NINTFVETPVQK 12 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 NINTFVET(1)PVQK;NINT(0.002)FVET(0.998)PVQK 188.39 0.00066176 18150600.0 123101.0 126580.0 122000.0 113544.0 126621.0 85195.0 103065.0 70572.0 69060.0 65742.0 True False 143939.567944423 139146.0258619235 124908.94268757639 107182.4977946145 101810.52400645388 80727.22422277405 93301.9370740177 68719.55977721482 70069.87185131582 77660.5041866142 1.8534462202118032 1.791721896725815 1.6083972669997946 1.3801416681130534 1.3109691351192934 1.0394887989497297 1.2014078205031729 0.8848714091796939 0.9022587811552385 1.0 16.244893453074063 -5.8662341859052045 0.571605966470378 0.9255082392142421 2.031804002744933 0.9469296827843021 0.07804704455642245 0.28037183320494247 0.15563140352001878 0.05196523288026764 0.17916734645328822 1.360710744500021e-06 5.8662341859052045 1.106295763530691 NINTFVET(ph)PVQK ddPTM_PC-9_Lapatinib_30min_R1 2 NINTFVETPVQK 12 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 NINT(0.003)FVET(0.997)PVQK;NINTFVET(1)PVQK 187.08 0.00077157 25818000.0 68813.0 128809.0 135562.0 101415.0 111803.0 106813.0 92310.0 90013.0 94900.0 61179.0 True False 67831.71400124143 128510.75067450125 124416.61564445304 108873.39741052235 105226.96735315528 102244.85698326431 97089.36012370106 94195.33258861228 84211.3626586972 71753.70863410666 0.9453408791333053 1.790998028127236 1.7339398619643491 1.5173208393408617 1.4665021412306178 1.4249417755483695 1.3530918745787532 1.3127590807736793 1.1736168661067512 1.0 16.130765779836196 -8.083024580327736 0.7189515494885595 1.0050957130923774 1.5261227982503154 0.35047354655811425 0.21369453307761987 0.6949970167206828 0.7595373543793752 0.20251817274037362 0.0878296857920477 8.25991198559641e-09 8.083024580327736 0.5210270851579379 NIPCAAVS(ph)PNR ddPTM_PC-9_AZD4547_30min_R2 2 NIPCAAVSPNR 11 0 Q13118-2;Q13118 Q13118-2 KLF10 Krueppel-like factor 10 1 NIPCAAVS(1)PNR;NIPCAAVS(1)PNR 76.868 0.020136 13896000.0 40740.0 33048.0 83730.0 118013.0 95965.0 75986.0 60553.0 94763.0 59755.0 75612.0 True False 53694.47255535796 43730.11971113656 82619.68549178982 90806.92613267455 82641.91622647704 71234.58340790673 65942.09969329547 80119.55578710735 62913.5273077497 72964.84689450168 0.7358950897682779 0.5993313434120545 1.1323217824502239 1.2445297975334664 1.1326264597795597 0.976286341159645 0.903751635203727 1.098056930112531 0.8622443544452992 1.0 16.154913947297786 -5.260178888571557 24.998319883735228 1.0501679706858886 0.6676131912999869 0.6390175918334629 0.11299191762831877 68.6533882998732 1361511.1161814774 0.03135993061270066 0.07408003684301188 5.493145612005031e-06 5.260178888571557 -0.38255477938590177 NIPCAAVS(ph)PNR ddPTM_PC-9_Lapatinib_30min_R1 2 NIPCAAVSPNR 11 0 Q13118-2;Q13118 Q13118-2 KLF10 Krueppel-like factor 10 1 NIPCAAVS(1)PNR;NIPCAAVS(1)PNR 92.15100000000001 0.0078033 11773400.0 68554.0 64158.0 60759.0 47713.0 65131.0 51431.0 49385.0 46028.0 65315.0 51871.0 True False 67576.4073887362 64009.44609285579 55763.62955652254 51221.973185902076 61300.12263247276 49231.416021516736 51941.91365733915 48166.62891347518 57958.53690255861 60836.83323623704 1.110781146782058 1.0521495398075553 0.916609668685176 0.8419565986776586 1.0076152779753789 0.8092369934895359 0.853790555725381 0.7917346507244736 0.9526882616900579 1.0 15.892657437390262 -5.210639828427156 2.5478025480728035 0.8838317001775587 1.1054440345256393 0.5249394182216953 0.07107843797479248 0.21891038644935853 2.681186227846521 0.018826498104894975 0.06794656880162682 6.1568726630911e-06 5.210639828427156 0.2216123343480806 NIPGITLLNVSK ddPTM_PC-9_Lapatinib_30min_R1 2 NIPGITLLNVSK 12 0 P36578;H3BM89 P36578 RPL4 60S ribosomal protein L4 0 ; 154.28 0.0011937999999999999 17253900.0 58417.0 62992.0 55231.0 47842.0 59844.0 49712.0 55198.0 52467.0 53018.0 54465.0 False True 57583.96286763425 62846.14589421691 50690.1203778254 51360.46027623346 56324.093577830805 47585.93364433199 58055.88235411176 54904.808360200375 47046.554535709256 63879.2026799493 0.901450870577459 0.9838279636815715 0.7935308872246811 0.804024754873071 0.8817281871852491 0.7449362491693793 0.9088385565014983 0.8595099196100979 0.736492513399458 1.0 15.963058685146718 -5.26127676231288 24.999998634850808 0.8352221734684198 0.942639419466072 0.21455768644475504 0.07702424422756822 18.74881654074711 2881742.2931279573 0.018609326348504013 0.0434140140650728 5.4792767643768545e-06 5.26127676231288 0.10741724599765223 NIPS(ph)PGQLDPDTR ddPTM_PC-9_AZD4547_30min_R2 1 NIPSPGQLDPDTR 13 0 Q9P2D1 Q9P2D1 CHD7 Chromodomain-helicase-DNA-binding protein 7 1 NIPS(0.769)PGQLDPDT(0.231)R 93.71600000000001 0.0039835 2305000.0 11208.0 14329.0 14605.0 16387.0 13246.0 14162.0 12819.0 16385.0 13152.0 15426.0 True False 14771.91085911762 18960.569031132778 14411.328157262526 12609.230326626193 11407.021542603188 13276.447901228868 13959.866166306463 13853.074739843103 13847.187869659849 14885.940435308972 0.9923397801645855 1.2737232903444191 0.9681167420957374 0.8470563469888341 0.7662949876882551 0.8918783437919422 0.9377886621925552 0.9306146830323232 0.9302192179148295 1.0 13.861662747816577 -5.472473758476203 6.7823697090400055 0.8941213718262162 1.1321601772968153 0.5317036878427278 0.08599402256465435 0.16371517957396445 17.822134345586946 0.02235157919964293 0.04620072507847649 3.3691957293287758e-06 5.472473758476203 0.23803880547059908 NIPS(ph)PGQLDPDTRIPVINLEDGTR ddPTM_PC-9_Lapatinib_30min_R1 1 NIPSPGQLDPDTRIPVINLEDGTR 24 1 Q9P2D1 Q9P2D1 CHD7 Chromodomain-helicase-DNA-binding protein 7 1 NIPS(0.717)PGQLDPDT(0.279)RIPVINLEDGT(0.004)R 48.213 0.018072 2528100.0 7280.2 4517.8 7657.8 6115.9 5824.9 4560.7 3042.1 4306.8 5841.1 3752.2 True False 7176.38301297483 4507.339311672807 7028.205243962839 6565.683688044318 5482.290834194017 4365.649492510965 3199.6050528903816 4506.909650746388 5183.213808490159 4400.762770507774 1.6307134438302833 1.0242177428602304 1.5970425152346719 1.49194219966707 1.245759228589696 0.9920210927450748 0.7270569262067269 1.0241201095750878 1.177798958677362 1.0 12.103537887924526 -6.6208342373145666 3.186407232912238 0.9680934864554336 1.4153287240958292 0.5668206093485477 0.18603335717481442 0.1918197991026556 3.890753328884041 0.06551676789382514 0.06575968247331364 2.3942294179509165e-07 6.6208342373145666 0.44723523764039563 NIPSPGQLDPDT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 NIPSPGQLDPDTR 13 0 Q9P2D1 Q9P2D1 CHD7 Chromodomain-helicase-DNA-binding protein 7 1 NIPS(0.46)PGQLDPDT(0.54)R 94.40899999999999 0.0092307 2373200.0 12137.0 11718.0 14686.0 13942.0 11462.0 16275.0 17368.0 17841.0 14826.0 16569.0 True False 15996.313534717214 15505.61434202066 14491.254044338066 10727.887301752755 9870.699148521655 15257.32167719954 18913.718353725766 15084.08339539461 15609.67209212111 15988.924353211087 1.0004621437529437 0.969772199773191 0.9063307652354837 0.6709574118160271 0.6173460409511102 0.9542431585859233 1.1829262516916772 0.9434082657577427 0.9762803142530466 1.0 13.964785265053983 -6.990973654339559 24.999216842286167 1.0277444617216547 0.8306627479188213 0.3438472408999015 0.12630559395208005 250.99126204717672 695137.7545378477 0.04963478287390626 0.04371336432892217 1.0210014189657685e-07 6.990973654339559 -0.19708171380283335 NIPSPGQLDPDT(ph)RIPVINLEDGTR ddPTM_PC-9_AZD4547_30min_R2 2 NIPSPGQLDPDTRIPVINLEDGTR 24 1 Q9P2D1 Q9P2D1 CHD7 Chromodomain-helicase-DNA-binding protein 7 1 NIPS(0.172)PGQLDPDT(0.821)RIPVINLEDGT(0.006)R;NIPS(0.038)PGQLDPDT(0.955)RIPVINLEDGT(0.007)R 75.22399999999999 0.00020273 5983900.0 12438.5 8766.3 14494.0 30306.0 24470.1 16056.4 10487.0 16197.6 13171.6 20663.5 True False 16393.684263127638 11599.835040660155 14301.800089788632 23319.419923032496 21072.84899967192 15052.39076975648 11420.322683989063 13694.633103819504 13867.823885645646 19940.077154479914 0.8221474839902757 0.5817347119970413 0.7172389544428349 1.1694749093683094 1.0568087995054478 0.7548812701747584 0.5727321211203675 0.6867893738687338 0.6954749361403538 1.0 14.283383371540834 -6.9856926022102055 24.75464196769591 0.705670823444438 0.8661176772357361 0.09723605385861811 0.18388133818230973 458.94393682389665 794060.8089362188 0.07060708394491404 0.06224231861790869 1.033492662931151e-07 6.9856926022102055 0.16044685379129808 NISFNDKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NISFNDKK 8 1 P15311;E7EQR4;A0A2R8Y7M3;A0A2R8Y5S7;P35241;P35241-5;P35241-4;P26038 P15311;A0A2R8Y7M3;P26038 EZR;RDX;MSN Ezrin;Radixin;Moesin 0 59.931000000000004 0.04543 9777200.0 43142.0 44007.0 39430.0 62513.0 69283.0 52935.0 65650.0 58169.0 49936.0 46360.0 False True 50445.088506659486 48375.72412786897 40370.16073910774 59010.59927988052 55707.493502176956 50158.99541325832 59431.15673515987 56642.12538515005 50666.21953036947 54764.701014441904 0.9211241469821354 0.8833376834306443 0.7371565988913515 1.0775298355836715 1.0172153315962855 0.9159001050700702 1.0852091882960775 1.0342816510622974 0.9251619855828003 1.0 15.740958672732631 -5.771653191494847 24.999999674202737 1.0091041908782572 0.8508192821276608 0.5413055604644407 0.06775648043437235 153.83236538809078 376530.5609821819 0.019172545297434437 0.028802843763332364 1.6917913826846143e-06 5.771653191494847 -0.15828490875059642 NISSS(ph)PSVESLPGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NISSSPSVESLPGGR 15 0 Q92609;Q92609-2;C9J3F6 Q92609 TBC1D5 TBC1 domain family member 5 1 NISS(0.021)S(0.735)PS(0.244)VESLPGGR 223.14 3.5215999999999996e-24 12583000.0 22453.0 25786.0 25996.0 34281.0 39988.0 51064.0 46015.0 50907.0 44565.0 37293.0 True False 26253.849433035688 28345.863666262845 26615.843230379018 32360.346710501566 32152.638456259876 48386.11394696557 41656.12608024958 49570.745190425034 45216.678816303145 44053.925688774456 0.5959480119549375 0.6434355899748058 0.6041650730155269 0.7345621577317779 0.7298472940506369 1.0983383022161635 0.9455712613340185 1.1252287830288945 1.0263938595561979 1.0 15.42698296440175 -6.6566483794954 3.8332698195885437 1.041679873712672 0.6496756478926303 0.9092949489854879 0.059900753584633065 0.06432370268760818 1.782324011697175 0.020969438117363393 0.020725461488171008 2.2047107541305008e-07 6.6566483794954 -0.3920042258200417 NISSS(ph)PSVESLPGGR ddPTM_PC-9_Lapatinib_30min_R1 3 NISSSPSVESLPGGR 15 0 Q92609;Q92609-2;C9J3F6 Q92609 TBC1D5 TBC1 domain family member 5 1 NIS(0.006)S(0.033)S(0.57)PS(0.052)VES(0.34)LPGGR;NISS(0.01)S(0.492)PS(0.492)VES(0.005)LPGGR;NISS(0.005)S(0.797)PS(0.159)VES(0.038)LPGGR 142.57 6.1004999999999994e-06 41802000.0 158628.0 163169.0 143124.0 112321.0 156981.0 135684.0 136052.0 138785.0 147564.0 131272.0 True False 156365.93563118763 162791.19220557384 131356.89719461708 120581.46103187173 147747.68621652084 129881.11161485237 143096.1068524513 145233.45775955194 130943.78840219161 153962.19029105493 1.0156125691352442 1.0573452605333056 0.8531763346981224 0.7831887868308497 0.9596361674071667 0.8435909580743237 0.9294236889065943 0.9433059992521415 0.8504931513032609 1.0 17.232216574857503 -5.257374534210288 24.99677084984134 0.890985386827086 1.0364789276565525 0.450919342360927 0.062143674707548655 283.51530624651787 1743459.485498143 0.01561260693358313 0.038325072039389285 5.528731075147407e-06 5.257374534210288 0.14549354082946653 NISSSPS(ph)VESLPGGR ddPTM_PC-9_AZD4547_30min_R2 2 NISSSPSVESLPGGR 15 0 Q92609;Q92609-2;C9J3F6 Q92609 TBC1D5 TBC1 domain family member 5 1 NIS(0.001)S(0.019)S(0.069)PS(0.91)VESLPGGR;NIS(0.006)S(0.017)S(0.024)PS(0.925)VES(0.028)LPGGR 150.01 0.00013692 12921100.0 25438.6 39043.3 37325.9 67283.0 50623.2 36434.0 43908.9 55847.0 45581.6 42474.0 True False 33527.54564424962 51663.283191655144 36830.9341776902 51771.94386198754 43595.042500038515 34155.776220404805 47816.70703718963 47217.12938639109 47990.95031931927 40986.99818807945 0.8180044191184678 1.260479797876019 0.8986004295479734 1.263130898838177 1.06363101537691 0.8333319767325283 1.1666311062295973 1.1520026221418576 1.1708822905034513 1.0 15.322878713075355 NISSSPS(ph)VESLPGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NISSSPSVESLPGGR 15 0 Q92609;Q92609-2;C9J3F6 Q92609 TBC1D5 TBC1 domain family member 5 1 NIS(0.022)S(0.192)S(0.005)PS(0.774)VES(0.007)LPGGR;NISSS(0.018)PS(0.971)VES(0.011)LPGGR;NIS(0.002)S(0.015)S(0.418)PS(0.565)VESLPGGR 161.94 0.00031127 18424200.0 62156.3 82441.0 79453.0 78515.0 104958.0 70312.0 77879.0 75444.0 78679.0 72716.0 True False 72678.13394711596 90625.19764641205 81347.46084718057 74116.05909906463 84392.23334730737 66624.71494279816 70501.73732486698 73463.67493952556 79829.53152895565 85898.83518046074 0.8460898659967852 1.0550224279062914 0.9470147141842098 0.86282961746056 0.9824607419880814 0.7756183748339486 0.8207531240296013 0.8552348211147364 0.9293435861062099 1.0 16.39035094757481 -5.965270521116134 1.5585186071753405 0.8735769944823372 0.9584748106288438 0.06265263295964985 0.08180456961508348 0.760924185921754 3.7453813349224325 0.027497682508559725 0.04897083352406657 1.0832519484733822e-06 5.965270521116134 0.0848978161465066 NITSSS(ph)PER ddPTM_PC-9_AZD4547_30min_R2 2 NITSSSPER 9 0 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 1 NIT(0.074)S(0.032)S(0.098)S(0.796)PER;NIT(0.078)S(0.001)S(0.004)S(0.916)PER 106.16 0.0025881 93981000.0 277898.0 228626.0 349591.0 413610.0 381720.0 331520.0 283258.0 360373.0 297866.0 354599.0 True False 366263.783362516 302524.8834748944 344955.1949212986 318258.6047107992 328724.766966819 310790.00199233094 308467.41325654415 304685.6333977101 313610.5886545085 342184.59694153623 1.0703689956713447 0.8840984842067047 1.008096793381485 0.9300786989110883 0.9606650033490055 0.9082524601346413 0.9014649286193533 0.8904130581008209 0.9164953404027426 1.0 18.38441529441551 -4.749187872884316 24.962206924634135 0.9311770406203698 1.0703693207677023 0.4977408606498316 0.041262564932068334 473.8698151384074 965441.1298149043 0.010142093297599809 0.16986635081362597 1.781607889080663e-05 4.749187872884316 0.13919228014733254 NITSSS(ph)PER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NITSSSPER 9 0 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 1 NITSS(0.001)S(0.999)PER;NIT(0.069)S(0.028)S(0.093)S(0.81)PER;NIT(0.023)S(0.009)S(0.031)S(0.936)PER 111.5 0.002231 89953000.0 219998.0 200873.0 233072.0 233761.0 267191.0 240560.0 266428.0 233277.0 216982.0 186655.0 True False 257239.3162414376 220814.34391659094 238629.3204104822 220664.129033387 214836.84159664242 227944.6101183229 241190.0110683201 227153.72592741245 220154.95126038542 220494.07393983268 1.1666495686030627 1.001452510586954 1.0822482262067423 1.0007712456417341 0.9743429279431157 1.0337901878511404 1.0938616478832661 1.0302033150759282 0.9984619873296922 1.0 17.750380356466756 -4.75504177025133 24.994602169936613 1.0268941756836638 1.1666498024433059 0.5798394626070273 0.03637338236612073 165.47899869580394 646443.792547789 0.00938399970106314 0.08641826762869244 1.757754545773012e-05 4.75504177025133 0.13975562675964204 NITSSS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 2 NITSSSPER 9 0 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 1 NIT(0.002)S(0.001)SS(0.996)PER;NIT(0.003)S(0.001)S(0.004)S(0.993)PER 142.19 0.00067509 91173000.0 315000.0 281050.0 305990.0 278530.0 258410.0 276880.0 241090.0 256220.0 286950.0 228968.0 True False 310508.04223607486 280399.24599266046 280832.68335555715 299014.0253488428 243210.8318536074 265038.4878388046 253572.46053757012 268124.9165770965 254630.66928254158 268544.81371931743 1.1562615488103125 1.04414321806912 1.045757240536706 1.1134604359232636 0.9056619954232702 0.9869432373988141 0.9442463513840323 0.9984363982442803 0.9481868808260848 1.0 18.034803334103145 -6.253030895263972 24.998986534433534 0.9640025281950655 1.0834834171874377 0.7005047595573475 0.04027163289918596 357.9679607484945 1064262.2191275707 0.01156021753205772 0.014689241178132192 5.584304671531254e-07 6.253030895263972 0.11948088899237219 NIYAFMGT(ph)PVQK ddPTM_PC-9_AZD4547_30min_R2 2 NIYAFMGTPVQK 12 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 NIYAFMGT(1)PVQK;NIYAFMGT(1)PVQK 104.17 0.007418600000000001 17873800.0 101684.0 105639.0 106250.0 142881.0 123491.0 132549.0 90220.0 130099.0 116400.0 117344.0 True False 134017.39684140924 139784.74086676218 104841.05557748329 109941.99293944446 106346.40625982283 124260.69007625963 98249.40522070129 109995.18892760748 122552.6663646902 113235.82227673389 1.1835247375507005 1.2344568887851242 0.9258647437669074 0.9709117726964553 0.9391586877863244 1.0973620147569767 0.8676530381047818 0.9713815532578841 1.0822782393471488 1.0 16.788970902973432 -5.257233583539696 24.90458470552474 0.97893918447394 1.2089908371970426 0.6555451216084829 0.06584002213578911 187.5874888130106 1110787.089426515 0.016537311358023634 0.04067315353457163 5.530525721076551e-06 5.257233583539696 0.23005165272310257 NIYAFMGT(ph)PVQK ddPTM_PC-9_Lapatinib_30min_R1 3 NIYAFMGTPVQK 12 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 NIYAFMGT(1)PVQK;NIYAFMGT(1)PVQK;NIYAFMGT(1)PVQK 98.25299999999999 0.014196 18609500.0 179817.0 193109.0 222274.0 176073.0 161406.0 165100.0 161119.0 124290.0 172352.0 120983.0 True False 177252.77660560058 192661.8679750812 203999.48972245204 189021.99578230924 151912.41641640532 158039.05786689746 169460.9534586782 130064.96714295293 152939.90281297988 141894.7503502857 1.2491848794125855 1.357780097568587 1.4376817269057007 1.3321281817381108 1.0705992719349355 1.113776637097267 1.1942721844207889 0.9166298740571486 1.077840458758536 1.0 17.114461689742903 -6.249027610780726 5.087563973888196 1.0660892091891359 1.3542175866961739 0.7497922701592181 0.07978935749940472 0.09487773786610801 7.716671172137394 0.025191066257774175 0.03122143616284109 5.636018230404098e-07 6.249027610780726 0.288128377507038 NIYS(ph)EELR ddPTM_PC-9_AZD4547_30min_R2 2 NIYSEELR 8 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 NIY(0.001)S(0.999)EELR;NIY(0.01)S(0.99)EELR 84.65799999999999 0.013811000000000002 9529000.0 30352.0 32189.0 29626.0 50177.0 39893.0 37198.0 26991.0 36862.0 30817.0 35137.0 True False 40003.304639180795 42593.46475979713 29233.139882715477 38609.46787692213 34354.54555330435 34872.00317962939 29393.146711504607 31165.824904491714 32445.923705847574 33906.86432487045 1.1797995903100555 1.256190025467944 0.8621599332402193 1.1386917854448237 1.0132032624469356 1.0284644090208903 0.8668789431508989 0.9191597490668519 0.9569131310691186 1.0 15.04928975099235 -3.9196024636025917 0.4595838862579166 0.9406908088205402 1.7548945965307363 0.442522962229456 0.09396726160302532 9.25866565615825 0.8282237509153786 0.060615152655768965 4.835554788959191 0.00012033654448867934 3.9196024636025917 0.8142037877101961 NIYS(ph)EELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NIYSEELR 8 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 NIY(0.001)S(0.999)EELR;NIY(0.001)S(0.999)EELR 87.29799999999999 0.01183 8267000.0 34189.0 32189.0 34806.0 34943.0 39999.0 34864.0 34780.0 37668.0 27894.0 25468.0 True False 39976.52243646985 35384.51119031005 35635.90704249007 32985.256996734504 32161.48308522403 33035.670465435694 31485.386614605697 36679.25491254504 28301.896979736557 30085.14679542294 1.328779371040056 1.1761455388907505 1.184501683997487 1.0963967442483205 1.0690153285247381 1.0980724372088368 1.0465425623050568 1.2191815171108058 0.9407265708951873 1.0 14.876763775722635 -1.5228787452803383 0.4439422223218574 1.0583362355402743 6.710214797971726 0.5981615628766603 0.06831678672502814 60.66616486563671 0.7406168974233258 0.04124746139183784 309.5864623698001 0.02999999999999995 1.5228787452803383 5.651878562431452 NIYS(ph)EELR ddPTM_PC-9_Lapatinib_30min_R1 2 NIYSEELR 8 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 NIY(0.002)S(0.998)EELR;NIY(0.001)S(0.999)EELR 87.29799999999999 0.01183 7745600.0 33279.0 26384.0 35477.0 27858.0 32807.0 29082.0 27744.0 26679.0 31704.0 27026.0 True False 32804.43535737885 26322.90946902814 32560.218005180268 29906.770251563717 30877.356761043666 27838.230653453138 29180.448567565403 27918.603736477886 28133.16166207943 31697.40809011862 1.0349248513983493 0.8304435931855914 1.027220204018215 0.9435083829736501 0.9741287575708565 0.8782494320767966 0.920594153458943 0.8807850678863947 0.8875540101605244 1.0 14.952077254980011 -6.753512820870806 24.923387078587446 0.9064329494557167 0.9573249773007073 0.12673903313726542 0.061841014477294266 340.8148708814346 1071618.9999306519 0.019325449605319088 0.01899382085203265 1.7639536897733583e-07 6.753512820870806 0.050892027844990584 NIYSEELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NIYSEELR 8 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ;; 158.07 1.1057e-17 5464400.0 72672.0 78409.0 67722.0 86251.0 88109.0 75628.0 81631.0 79492.0 63504.0 62259.0 False True 84973.93426257372 86192.92733297142 69336.74931711535 81418.63609951474 70844.67394574876 71661.93454451494 73898.32072273946 77405.4192287361 64432.62586223531 73546.06385802719 1.1553838479596517 1.1719584001036092 0.9427662838756745 1.1070427406786134 0.963269415512254 0.9743816430863063 1.0047896086647445 1.0524753490296772 0.8760853060282818 1.0 16.166360510907722 -5.252108292035306 24.942410736840436 0.995156778338015 1.163671151059499 0.5823109457946984 0.05867596386362705 434.4949491771703 1161418.7250966972 0.014311272425005187 0.03676312914658683 5.596180424272711e-06 5.252108292035306 0.16851437272148406 NIYSEELR ddPTM_PC-9_Lapatinib_30min_R1 4 NIYSEELR 8 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ;;; 163.15 9.261799999999999e-05 50686900.0 225048.0 159580.0 183104.0 177039.0 178982.0 181748.0 175403.0 168473.0 177595.0 163411.0 False True 221838.77425125142 159210.5023145659 168049.89592187954 190059.0386447911 168454.63065215087 173975.06171528102 184484.50908652938 176300.87062092396 157592.38094174216 191656.37361852924 1.1574818518313246 0.8307081017376273 0.8768291539125342 0.9916656308184278 0.8789409267830619 0.9077447226543015 0.9625795667705022 0.9198800295148614 0.8222652759537876 1.0 17.548162450842646 -4.749966912931039 24.99513134205219 0.9096712602534387 1.1574823973957225 0.6205429876269283 0.058040971140928654 337.3030804930869 734837.8962027511 0.014053610142290096 0.21769793512163327 1.7784148948246906e-05 4.749966912931039 0.24781113714228375 NIYVLQELDNPGAK ddPTM_PC-9_Lapatinib_30min_R1 2 NIYVLQELDNPGAK 14 0 P12956;B1AHC9 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 ; 225.79 8.9223e-20 12300100.0 86053.0 70637.0 76026.0 70605.0 73732.0 58669.0 76544.0 67432.0 59740.0 68710.0 False True 84825.8684398125 70473.44436642442 69775.43574884691 75797.52723137553 69395.22872268938 56159.86363411882 80507.07378733167 70565.13689261889 53011.452109911195 80586.43194967989 1.0526073234360322 0.8745075648767988 0.8658459502514813 0.9405743050977283 0.8611279472705956 0.6968898147666643 0.9990152416426903 0.8756453808090358 0.6578210602873301 1.0 16.29824933732666 NKAGT(ph)PVSELTK ddPTM_PC-9_AZD4547_30min_R2 1 NKAGTPVSELTK 12 1 O75113 O75113 N4BP1 NEDD4-binding protein 1 1 NKAGT(0.989)PVS(0.011)ELTK 59.975 0.044612 6423500.0 44963.0 33258.0 54197.0 91968.0 72565.0 59238.0 48817.0 55302.0 38982.0 64461.0 True False 59260.298711501215 44007.99810436278 53478.31236830929 70766.19849143586 62490.60231307574 55533.83849548058 53161.61842894002 46756.34661353698 41042.50893666969 62204.24001040136 0.9526729801954356 0.707475858510675 0.8597213366704106 1.137642682871824 1.0046035817273307 0.8927661279391019 0.8546301412902192 0.7516585140453241 0.6598024335609092 1.0 15.924725301279885 -7.431462758460553 2.6841302011272825 0.7815236959087815 0.92683095931916 0.14603814208027155 0.12986295864122727 0.5131368773789224 7.207483651238573 0.06934725749547838 0.04112328819342324 3.702859567310781e-08 7.431462758460553 0.14530726341037858 NKAGT(ph)PVSELTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NKAGTPVSELTK 12 1 O75113 O75113 N4BP1 NEDD4-binding protein 1 1 NKAGT(0.987)PVS(0.012)ELT(0.002)K 63.211999999999996 0.034933 9498700.0 66305.0 31267.0 40259.0 76083.0 83739.0 79327.0 70245.0 73956.0 74976.0 63971.0 True False 77529.1269165558 34370.981123595775 41218.927243107726 71820.31617441418 67330.9440754412 75166.9524727977 63590.88507024077 72014.73336285932 76072.38215934345 75568.43590584256 1.0259458990676509 0.4548325066092626 0.5454516392858264 0.9504009883690263 0.8909929558332373 0.9946871543888363 0.8415006121004583 0.9529737184528854 1.0066687400296177 1.0 16.205496142157017 -5.773868590276873 24.996371175934286 0.9413261744606622 0.6533522719072776 0.4201574813958723 0.14599827246721347 191.78881933585058 385706.09762340615 0.040098425010723034 0.05994596270461222 1.6831832851073852e-06 5.773868590276873 -0.2879739025533846 NKAS(ph)PQSEFMPSK ddPTM_PC-9_AZD4547_30min_R2 1 NKASPQSEFMPSK 13 1 Q9NQW6;Q9NQW6-2;H7C1K5 Q9NQW6 ANLN Actin-binding protein anillin 1 NKAS(0.969)PQS(0.026)EFMPS(0.005)K 68.123 0.015829 13865000.0 64413.0 53283.0 51379.0 71566.0 65020.0 61627.0 53882.0 68982.0 73758.0 69667.0 True False 84894.99412636911 70505.68774414473 50697.68088955777 55067.56438367792 55993.09532689565 57773.453947820366 58677.39361673486 58322.41694866378 77656.6973000586 67227.97953498458 1.2627925859677345 1.0487551199936698 0.7541157898873838 0.8191167541339163 0.8328838039488835 0.8593662095371437 0.8728120943483046 0.8675319019265414 1.1551246644211142 1.0 16.036774171114153 -4.9353856969579155 3.490922756277117 0.8834430588178939 1.2594846170352787 0.5313787553169587 0.10655465539258922 0.18553813971725633 4.2549535032402765 0.02735370624190399 0.14866568280288908 1.160417589144389e-05 4.9353856969579155 0.37604155821738483 NKAS(ph)PQSEFMPSK ddPTM_PC-9_Lapatinib_30min_R1 1 NKASPQSEFMPSK 13 1 Q9NQW6;Q9NQW6-2;H7C1K5 Q9NQW6 ANLN Actin-binding protein anillin 1 NKAS(1)PQSEFMPSK 78.234 0.0071839 10442000.0 79150.0 55143.0 62307.0 51767.0 85726.0 79988.0 65001.0 70337.0 76615.0 75758.0 True False 78021.30648566777 55015.31977147584 57184.35897197533 55574.11786964963 80683.76522380063 76567.09970113513 68366.4337276643 73605.11379784285 67985.81190828336 88852.66935881015 0.8780974960988226 0.6191746423431546 0.6435862803519165 0.6254636835414242 0.9080623666800446 0.8617310009217315 0.7694359012623796 0.8283950761299729 0.7651521602996416 1.0 16.43912749866068 -6.259775699668883 24.998048688257356 0.8428945755649749 0.6829805146042284 0.4182207783289975 0.09377419182310853 153.06808534084377 2299961.545448611 0.027855846725288468 0.03409575029174538 5.498247688672039e-07 6.259775699668883 -0.15991406096074656 NKASPQSEFMPS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NKASPQSEFMPSK 13 1 Q9NQW6;Q9NQW6-2;H7C1K5 Q9NQW6 ANLN Actin-binding protein anillin 1 NKAS(0.003)PQS(0.014)EFMPS(0.982)K 92.838 0.043483 0.0 16282.0 14932.0 12482.0 23052.0 23080.0 18990.0 21736.0 22145.0 19725.0 16780.0 True False 19038.221015841395 16414.350277849888 12779.61821824861 21760.471175592356 18557.6396811663 17994.130970015587 19677.008724987598 21563.717214566994 20013.440808966225 19822.081169593086 0.9604552041208404 0.8280841016345635 0.6447162691399146 1.0977894293447221 0.9362104575393209 0.9077821251997716 0.9926812707826044 1.0878634301854018 1.0096538621618947 1.0 14.274820822165983 -5.775266760855301 24.99980126186298 1.0008532852641907 0.8127850302250126 0.4945475074220964 0.08957736685404798 198.20536800856917 358353.4411083578 0.026148638836898278 0.03901110809153588 1.6777731468997115e-06 5.775266760855301 -0.18806825503917812 NKDQGTYEDYVEGLR ddPTM_PC-9_AZD4547_30min_R2 2 NKDQGTYEDYVEGLR 15 1 F8W1R7;G3V1V0;P60660-2;P60660;J3KND3;G8JLA2;B7Z6Z4;G3V1Y7;F8VPF3;F8VZU9;F8W180 F8W1R7 MYL6 Myosin light polypeptide 6 0 ; 101.75 0.0020903000000000002 58944000.0 121583.0 112992.0 140242.0 173978.0 166977.0 148128.0 129526.0 153093.0 131070.0 154046.0 False True 160243.8649164969 149514.45432101024 138382.29944750504 133870.06003330517 143795.1257828218 138865.53274348463 141053.56307488948 129435.99457716181 137998.0926152918 148652.89642795332 1.0779733780307557 1.0057957692971995 0.9309088673867443 0.9005546696373127 0.967321385846754 0.9341596166663845 0.9488786728299844 0.8707263543962949 0.9283242770999385 1.0 17.181588048153507 -4.978310049402979 2.2982309410625237 0.9305944616037202 1.0866789140599653 0.6488500395019539 0.03335759516510217 0.2324216998648833 1.984248811372929 0.00878724752263042 0.06248859657724188 1.051211130337204e-05 4.978310049402979 0.15608445245624514 NKDQGTYEDYVEGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NKDQGTYEDYVEGLR 15 1 F8W1R7;G3V1V0;P60660-2;P60660;J3KND3;G8JLA2;B7Z6Z4;G3V1Y7;F8VPF3;F8VZU9;F8W180 F8W1R7 MYL6 Myosin light polypeptide 6 0 ; 103.13 0.0017425999999999997 37851000.0 77721.0 96271.0 84555.0 125033.0 127897.0 119926.0 127549.0 129894.0 106022.0 97065.0 False True 90877.63024027804 105828.14864712607 86571.11187662322 118027.80637245529 102836.50096629678 113636.86944234284 115466.6353452079 126484.42013406927 107572.37117608204 114662.11613388278 0.7925689260275531 0.9229565284104655 0.7550105893348446 1.0293531146297932 0.8968655422879334 0.9910585402911731 1.007016434359067 1.1031055801061829 0.9381683750758398 1.0 16.807029284328927 -6.05095420473124 0.8470977312937448 1.0187072373018626 0.8208732351675513 0.4818328007879352 0.07315011648499373 0.5794666844627112 0.8489524662418271 0.033968271702897616 0.07452224555863748 8.892948868394141e-07 6.05095420473124 -0.19783400213431135 NKDQGTYEDYVEGLR ddPTM_PC-9_Lapatinib_30min_R1 2 NKDQGTYEDYVEGLR 15 1 F8W1R7;G3V1V0;P60660-2;P60660;J3KND3;G8JLA2;B7Z6Z4;G3V1Y7;F8VPF3;F8VZU9;F8W180 F8W1R7 MYL6 Myosin light polypeptide 6 0 ; 102.65 0.0018648 65997000.0 310210.0 260050.0 257990.0 215480.0 256630.0 233030.0 209158.0 239020.0 232170.0 216444.0 False True 305786.3485144536 259447.8702024246 236779.05807019878 231327.11802020847 241535.52795399245 223063.85011946163 219987.1778220461 250125.7417854097 206020.56974151445 253856.0570064982 1.2045658950206815 1.0220274956676856 0.9327295982704786 0.9112530965305546 0.9514664759321053 0.878702098936925 0.8665823475561778 0.9853053920986686 0.8115645227099733 1.0 17.95365115762425 -4.600183050740425 1.354204294988293 0.9109257023299752 1.437165351796609 0.736430816149172 0.052939962791496445 0.9077898383133834 1.0957702331720138 0.014314538731424343 0.7377860699204873 2.5108279198249363e-05 4.600183050740425 0.5262396494666338 NKDSGSDTASAIIPSTTPS(ph)VDSDDESVVK ddPTM_PC-9_Lapatinib_30min_R1 2 NKDSGSDTASAIIPSTTPSVDSDDESVVK 29 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 NKDSGSDTASAIIPS(0.001)T(0.018)T(0.007)PS(0.778)VDS(0.185)DDES(0.012)VVK;NKDSGSDTASAIIPS(0.012)T(0.012)T(0.012)PS(0.542)VDS(0.387)DDES(0.035)VVK 98.37700000000001 4.9329e-11 4538800.0 43623.0 46923.0 40930.4 45193.9 47368.4 42548.1 37543.0 31766.1 47284.7 34154.0 True False 43000.928020521584 46814.3526764405 37565.260507913066 48517.61016843084 44582.283841857534 40728.41694746546 39486.792840690185 33242.06897384949 41958.99915603476 40057.47339265566 1.0734807859450664 1.1686796173476004 0.9377840718930733 1.211199959938719 1.1129579593013341 1.0167495225730543 0.9857534561311072 0.829859353534371 1.0474699376253656 1.0 15.289783806220768 -7.025545724558893 2.5879144804458805 0.9514436719079304 1.1010929996688315 0.3575378835253412 0.08483891220433712 0.2943042736572448 3.9401362421717767 0.03434574744761824 0.0269900447590554 9.428753358986215e-08 7.025545724558893 0.149649327760901 NKDSGSDTASAIIPSTTPSVDS(ph)DDESVVK ddPTM_PC-9_AZD4547_30min_R2 1 NKDSGSDTASAIIPSTTPSVDSDDESVVK 29 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 NKDSGSDTASAIIPS(0.016)T(0.019)T(0.006)PS(0.306)VDS(0.327)DDES(0.327)VVK 58.272 0.00080193 6850100.0 17312.0 23430.0 20746.0 20714.0 19731.0 25247.0 23073.0 22018.0 26086.0 20514.0 True False 22816.855888030375 31003.28930137769 20470.89448480441 15938.707328109793 16991.6912318514 23668.30109887907 25126.452301676327 18615.624023305787 27464.85270437551 19795.811103975644 1.152610305694825 1.5661540281696877 1.0341023349476792 0.8051555576274811 0.8583478162427461 1.1956216885766153 1.2692812721692477 0.9403819790726919 1.3874072933975246 1.0 14.272907560416316 -5.2866279019296565 24.48243788667752 1.0549886179311205 1.3593821841949918 0.27215320033788803 0.19477916873226236 665.4295565981186 646775.36750366 0.0521033479377421 0.1085339846618853 5.168590179473579e-06 5.2866279019296565 0.30439356626387126 NKEEAAEYAK ddPTM_PC-9_Lapatinib_30min_R1 1 NKEEAAEYAK 10 1 P62753;A2A3R5 P62753 RPS6 40S ribosomal protein S6 0 90.913 0.010897 23212000.0 52425.0 43717.0 46288.0 38480.0 43697.0 39299.0 46862.0 41509.0 41173.0 36343.0 False True 51677.40988643244 43615.77597246446 42482.37931684713 41309.94756551697 41126.82837160739 37618.27338044344 49288.285062473005 43437.65967605461 36535.66316908894 42624.83912599646 1.2123778281878583 1.0232478729958099 0.9966578217755091 0.9691519877273261 0.9648559200432161 0.882543468826852 1.1563277674029406 1.0190691757839954 0.8571448929365274 1.0 15.379406768699395 -4.676854200271171 2.2794459746464444 0.9831049227561864 1.3159436332353789 0.45071187950655167 0.07637195573474245 0.8768642164741317 4.177254896698419 0.020382753942481104 0.6549187071487336 2.1044848310096584e-05 4.676854200271171 0.33283871047919245 NKELYEINPPEISEEIIGS(ph)PIPEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NKELYEINPPEISEEIIGSPIPEPR 25 1 Q86YS7-3;Q86YS7;Q86YS7-2;Q86YS7-4;Q86YS7-5 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 NKELYEINPPEIS(0.021)EEIIGS(0.979)PIPEPR;NKELYEINPPEIS(0.165)EEIIGS(0.835)PIPEPR 81.441 0.00030291 0.0 4378.5 4153.9 4976.200000000001 7412.1 7848.1 8961.3 8449.8 12020.5 8209.3 5609.5 True False 5119.693570683062 4566.271739831273 5094.851480343592 6996.824067352429 6310.3211430572455 8491.353652532945 7649.373772745688 11704.974611772534 8329.345482030232 6626.457945222437 0.7726139082153647 0.6890969168714755 0.7688649837454854 1.0558920203209046 0.9522917364331693 1.2814317577696341 1.1543684176341533 1.7663998939601844 1.256983074650847 1.0 12.694022194158846 -6.3981339799940775 0.9423679629742955 1.3652753177266863 0.7205121185237638 0.5690646839317257 0.19856252811118166 0.3718554818533817 0.7127165687262986 0.09850474645195632 0.1342405616078533 3.9982138570087136e-07 6.3981339799940775 -0.6447631992029225 NKHEAMITDLEER ddPTM_PC-9_AZD4547_30min_R2 2 NKHEAMITDLEER 13 1 P35579 P35579 MYH9 Myosin-9 0 ; 65.043 0.027819999999999998 14722000.0 83212.0 65429.0 76990.0 116645.0 103304.0 95996.0 80509.0 95130.0 77606.0 91919.0 False True 109671.68508287806 86577.64471616915 75969.06229562762 89754.2973972853 88962.02275683843 89993.35494466647 87674.14503340103 80429.84436992806 81708.09472421098 88700.94378796619 1.2364207233808138 0.9760622719317097 0.8564628407700678 1.0118753371084426 1.00294336179214 1.0145704329797178 0.9884240380009974 0.9067529716728872 0.9211637580714908 1.0 16.436661834594105 -4.763691533568243 5.980870018571814 0.9623024826897316 1.2462973497214667 0.7282069181826651 0.04993665300729255 0.07164698412429557 9.83037312460637 0.013176259596920526 0.08354190444572973 1.7230920013661916e-05 4.763691533568243 0.28399486703173504 NKHEAMITDLEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NKHEAMITDLEER 13 1 P35579 P35579 MYH9 Myosin-9 0 ; 84.89200000000001 0.0057218 18192500.0 88959.0 81798.0 80955.0 112746.0 104862.0 83987.0 109410.0 87944.0 94922.0 88526.0 False True 104018.0016796605 89918.3648558508 82885.27422354715 106429.20714746362 84315.0438581654 79582.57386933651 99045.89274019597 85635.56318437029 96310.05467521874 104575.0630285698 0.9946730957383492 0.8598451892042867 0.7925911954832193 1.0177302701542457 0.8062633807366735 0.7610090930339161 0.9471272583707335 0.8188908589132262 0.9209657817648834 1.0 16.674179341947593 -8.533229545500918 20.47485906106418 1.0000000058030765 0.8724629206264973 0.17948346182938502 0.08235635574884757 193.13964885000212 382052.3485418018 0.07743437962419432 0.019993470843509043 2.929344536664461e-09 8.533229545500918 -0.12753708517657913 NKHEAMITDLEER ddPTM_PC-9_Lapatinib_30min_R1 2 NKHEAMITDLEER 13 1 P35579 P35579 MYH9 Myosin-9 0 ; 74.475 0.008759000000000001 13344600.0 141293.0 122789.0 134935.0 114738.0 131299.0 134612.0 117921.0 112953.0 136553.0 105327.0 False True 139278.13591003694 122504.68961463385 123841.16516416248 123176.21527474743 123576.25096376613 128854.95855589844 124026.37238811553 118201.20873519935 121172.96317316206 123532.63161059444 1.1274602839278633 0.9916787816906474 1.0024975874758388 0.9971148001042306 1.0003530998457897 1.0430843808304942 1.0039968449719219 0.9568419873689645 0.9808984200638529 1.0 16.914532659926024 -4.759765407847998 24.99951029815272 0.997915193456215 1.1274604445907435 0.7868369207259617 0.020309219593131585 21.25558169635466 317340.96132065856 0.0055645813694402 0.03458542945418543 1.738739787403952e-05 4.759765407847998 0.12954525113452842 NKPGPNIES(ph)GNEDDDASFK ddPTM_PC-9_AZD4547_30min_R2 8 NKPGPNIESGNEDDDASFK 19 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 NKPGPNIES(0.999)GNEDDDAS(0.001)FK;NKPGPNIES(1)GNEDDDASFK;NKPGPNIES(0.997)GNEDDDAS(0.003)FK;NKPGPNIES(1)GNEDDDASFK;NKPGPNIES(0.999)GNEDDDAS(0.001)FK;NKPGPNIES(1)GNEDDDASFK;NKPGPNIES(1)GNEDDDASFK;NKPGPNIES(1)GNEDDDASFK 108.5 8.607700000000001e-05 1493992000.0 959635.0 1045270.0 968628.3 1308900.0 1195538.0 1148493.0 1124047.0 1089421.0 1073329.3 1174212.0 True False 1264778.9683520133 1383133.0861310733 955783.6558515127 1007153.3273034132 1029558.185188037 1076677.5511528058 1224085.0054324241 921076.0168541111 1130063.2955528048 1133103.1952823182 1.116208103214189 1.2206594173326455 0.8435098054889648 0.8888451921208077 0.9086181995378785 0.9502025549266467 1.0802943725945786 0.8128791981957306 0.9973171907535254 1.0 20.111847827254344 -5.256130692514918 24.99928340097196 0.9316371081583548 1.1684337771992592 0.587174469141357 0.07817733331474974 283.0856350789909 1333075.9407985162 0.019697696888483295 0.04902755479109809 5.5445883419975145e-06 5.256130692514918 0.23679666904090446 NKPGPNIES(ph)GNEDDDASFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 NKPGPNIESGNEDDDASFK 19 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 NKPGPNIES(1)GNEDDDASFK;NKPGPNIES(0.999)GNEDDDAS(0.001)FK;NKPGPNIES(0.981)GNEDDDAS(0.019)FK;NKPGPNIES(0.998)GNEDDDAS(0.002)FK;NKPGPNIES(0.995)GNEDDDAS(0.005)FK;NKPGPNIES(1)GNEDDDASFK;NKPGPNIES(1)GNEDDDASFK;NKPGPNIES(0.998)GNEDDDAS(0.002)FK 117.02 3.038e-05 500163000.0 1368973.0 1471511.0 1103482.0 1643056.0 1525602.0 1361684.0 1600979.0 1564630.0 1314920.0 1115914.0 True False 1600713.0904507728 1617592.8872025951 1129793.1958587903 1551000.899179426 1226671.2397255914 1290274.8939323162 1449322.6790357933 1523560.1203625158 1334148.217415763 1318220.3746296335 1.2142985507263975 1.227103539237188 0.8570594246627514 1.1765869569533807 0.9305509635065656 0.9788006002371425 1.0994540115820879 1.1557704232803825 1.0120828376595261 1.0 20.33016014362191 -5.205975974658503 24.966312305025472 1.0347170166024957 1.2207014598765262 0.40970565314745744 0.09290365821761708 291.5475609354553 131236.006415649 0.023086312952958567 0.06108061874006753 6.223347120178591e-06 5.205975974658503 0.18598444327403052 NKPGPNIES(ph)GNEDDDASFK ddPTM_PC-9_Lapatinib_30min_R1 10 NKPGPNIESGNEDDDASFK 19 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 NKPGPNIES(1)GNEDDDASFK;NKPGPNIES(1)GNEDDDASFK;NKPGPNIES(1)GNEDDDASFK;NKPGPNIES(0.997)GNEDDDAS(0.003)FK;NKPGPNIES(1)GNEDDDASFK;NKPGPNIES(1)GNEDDDASFK;NKPGPNIES(1)GNEDDDASFK;NKPGPNIES(0.989)GNEDDDAS(0.011)FK;NKPGPNIES(0.997)GNEDDDAS(0.003)FK;NKPGPNIES(0.999)GNEDDDAS(0.001)FK 126.32 1.4442e-05 4076505800.0 952501.9 926673.0 757008.0 827244.0 866712.0 817729.9 782643.0 747705.7999999999 816915.6 713391.7000000001 True False 938919.0482385431 924527.3456031206 694769.7243753861 888082.2833650848 815733.7041813544 782757.4983985004 823164.4250383909 782446.9411022203 724905.9626253664 836700.5048103097 1.1221686168952505 1.104968074344263 0.8303684775867309 1.0614100006625715 0.9749410924119034 0.9355288946263527 0.9838220728993254 0.9351577256184525 0.866386429143737 1.0 19.674351779952197 -5.135836905892243 8.30810102527165 0.9520354987695412 1.1174829860598665 0.5308975843535964 0.06208218302654481 0.20988136484548797 13.0892442206745 0.015290069256817283 0.040857512464647805 7.314137055996529e-06 5.135836905892243 0.16544748729032532 NKPLS(ph)PIKLTPTSVLDYFGTGSVQR ddPTM_PC-9_AZD4547_30min_R2 2 NKPLSPIKLTPTSVLDYFGTGSVQR 25 2 P35251-2;P35251;A0A1W2PP02 P35251-2 RFC1 Replication factor C subunit 1 1 NKPLS(0.958)PIKLT(0.04)PT(0.002)SVLDYFGTGSVQR;NKPLS(0.947)PIKLT(0.047)PT(0.004)S(0.002)VLDYFGTGSVQR 55.881 0.0019018000000000001 10001700.0 34954.6 18135.9 32545.9 59127.0 45730.0 39294.7 31667.8 30959.4 32289.2 37889.0 True False 46069.435699153524 23997.975008145804 32114.320100886725 45496.18365304373 39381.17885725835 36837.596197176805 34486.172851342504 26175.33610623732 33995.94119229171 36562.51764251405 1.26001814616795 0.6563545553067033 0.8783399550020301 1.2443394652927788 1.0770915515803217 1.0075235123946416 0.9432111100369843 0.715906283100189 0.9298030711310212 1.0 15.158077795276755 -10.143367794817607 4.663197362169209 0.9999999816563419 0.9606038109226609 0.0012017662804350016 0.18611521731505684 259531931.89624783 952647251.2933728 83.18279845373158 0.047658378007511236 7.188399497932439e-11 10.143367794817607 -0.03939617073368096 NKPLS(ph)PIKLTPTSVLDYFGTGSVQR ddPTM_PC-9_Lapatinib_30min_R1 1 NKPLSPIKLTPTSVLDYFGTGSVQR 25 2 P35251-2;P35251;A0A1W2PP02 P35251-2 RFC1 Replication factor C subunit 1 1 NKPLS(0.987)PIKLT(0.009)PT(0.002)S(0.001)VLDYFGTGSVQR 51.758 0.005736 3017000.0 20549.0 8725.0 9992.4 7278.1 7531.9 9034.8 7109.3 6153.3 7410.4 7261.5 True False 20255.967491774925 8704.797798562398 9170.863443779452 7813.35575302987 7088.888450285141 8648.402665147467 7477.38476792794 6439.204781726053 6575.762717028551 8516.640599659455 2.378398765891903 1.0220928894088201 1.0768170074179433 0.9174222701545365 0.8323573558532686 1.0154711313629086 0.8779735014563054 0.7560733256706323 0.7721075745865675 1.0 13.056068754320005 -4.749104470647984 3.924694165387891 0.9047372806699338 2.5714462981081594 0.9517402436552094 0.09887543579184381 0.05954939773508379 1.6285655264014673 0.027489414883552693 0.29820661352178257 1.781950063243581e-05 4.749104470647984 1.6667090174382255 up NKPPPPPPASASPSAVPNGPQS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 NKPPPPPPASASPSAVPNGPQSPK 24 1 H0Y7W6 H0Y7W6 FNBP1 1 NKPPPPPPASASPSAVPNGPQS(1)PK;NKPPPPPPAS(0.003)AS(0.007)PS(0.02)AVPNGPQS(0.97)PK 156.11 6.202899999999999e-08 33410000.0 79092.0 79286.0 78527.0 98608.0 97210.0 105251.0 101213.0 86058.0 88121.0 103552.0 True False 104241.6107842014 104913.64897776504 77485.68067136969 75875.44907841309 83714.06946674151 98669.63833160831 110220.76092443848 72759.71351610722 92778.89615741295 99926.67599877599 1.0431810098984806 1.0499063231028534 0.775425379628547 0.7593112481730354 0.8377549701319689 0.9874203994618707 1.1030163849920174 0.7281310299663972 0.9284697527469983 1.0 16.608582244691746 -5.2329295343677815 23.904591928710232 0.8847936281154287 1.046543805428649 0.23390991613721202 0.11305715645823212 626.7386677687941 525496.0924027547 0.03028193331632271 0.08007710419758018 5.848849758548831e-06 5.2329295343677815 0.1617501773132204 NKPPPPPPASASPSAVPNGPQS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NKPPPPPPASASPSAVPNGPQSPK 24 1 H0Y7W6 H0Y7W6 FNBP1 1 NKPPPPPPASASPSAVPNGPQS(1)PK 159.5 9.026700000000001e-26 0.0 13360.0 12846.0 12056.0 19988.0 17240.0 17212.0 19335.0 18933.0 18116.0 15756.0 True False 15621.584127972073 14121.265983743608 12343.460762634608 18868.137161970324 13861.945758375514 16309.37242000571 17503.448826722277 18436.028811171687 18380.91222789516 18612.43807557262 0.8393088570419042 0.7587004951423679 0.6631834428416147 1.0137380758694525 0.7447678644834952 0.8762620111231153 0.9404167662319423 0.9905219690357248 0.9875606921168851 1.0 14.18397942845284 -7.17539995430276 0.7910052902056441 1.0125802276725766 0.7847670569117349 0.48674709295981444 0.08518433275028993 0.559296476284052 0.6995068934392793 0.06744265784126864 0.04403851237283494 6.677287037238783e-08 7.17539995430276 -0.22781317076084173 NKPPPPPPASASPSAVPNGPQS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 NKPPPPPPASASPSAVPNGPQSPK 24 1 H0Y7W6 H0Y7W6 FNBP1 1 NKPPPPPPASASPSAVPNGPQS(1)PK;NKPPPPPPASASPSAVPNGPQS(1)PK 131.83 1.6893000000000002e-07 24399000.0 112275.0 105827.0 75360.0 97724.0 95169.0 89917.0 92475.0 92133.0 83871.0 76138.0 True False 110673.93791128692 105581.96408349127 69164.19169801225 104910.94895770741 89571.34652945308 86071.45951676457 97262.90301634984 96413.8355280526 74424.56477921597 89298.35185249192 1.2393726828699414 1.182350646940243 0.774529319558569 1.1748363411119307 1.003057107676658 0.9638639205675631 1.0891903489665096 1.0796821388967452 0.8334371602082274 1.0 16.44634592783907 -5.025263914368362 24.85544397331541 1.0007766122333273 1.2251172817842748 0.3859631715809929 0.1118488966854021 581.6124883546069 572211.4231424927 0.02710500428186383 0.07241990941157744 9.434873586549087e-06 5.025263914368362 0.22434066955094756 NKPRPPPLSPLGGPVPSALPNGPPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 NKPRPPPLSPLGGPVPSALPNGPPSPR 27 2 Q15642 Q15642 TRIP10 Cdc42-interacting protein 4 1 NKPRPPPLSPLGGPVPS(0.001)ALPNGPPS(0.999)PR 73.317 2.8095e-05 12996000.0 38678.0 36833.0 38016.0 57383.0 47287.0 49289.0 41374.0 39321.0 38432.0 49659.0 True False 50976.799447622376 48738.546941427434 37511.88300078688 44154.23590851229 40722.01628303469 46206.95103824812 45056.20584794161 33244.84295669031 40463.43705951699 47920.45352502322 1.0637795700535928 1.0170719047134438 0.7827948243686558 0.9214068870499258 0.8497836161289744 0.9642427739987823 0.9402291200022563 0.6937505910567068 0.8443876066070136 1.0 15.548353941582779 -5.112454854761573 5.672558525695928 0.8703350840497716 1.0527157221076178 0.3785785263617957 0.08564026515828635 0.21424080949761437 9.082006987777566 0.022166925855782737 0.061931034941125826 7.71871748064274e-06 5.112454854761573 0.1823806380578462 NKPRPPPLSPLGGPVPSALPNGPPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NKPRPPPLSPLGGPVPSALPNGPPSPR 27 2 Q15642 Q15642 TRIP10 Cdc42-interacting protein 4 1 NKPRPPPLSPLGGPVPS(0.004)ALPNGPPS(0.996)PR;NKPRPPPLSPLGGPVPSALPNGPPS(1)PR 85.469 2.7395e-07 13297100.0 59593.0 60985.0 60202.0 72404.0 77665.0 65615.0 68263.0 62515.0 67933.0 49494.0 True False 69680.91788459868 67039.18776417592 61637.44399735643 68347.43861693506 62447.100772867365 62174.03389139405 61796.63445867814 60874.04749011764 68926.39160839048 58466.87040571159 1.1918017400464724 1.1466183720623244 1.0542285497691888 1.1689943063936983 1.0680766789728315 1.0634062240711333 1.0569512961761207 1.0411716424652497 1.178896546541631 1.0 15.83533174885516 -1.5228787477559345 0.464917743289741 1.0687764813994407 4.150910260570111 0.34602935662500134 0.05194737574482914 107.90683309861471 1.255545397693544 0.030284341380428164 318.6326607628394 0.029999999828991826 1.5228787477559345 3.08213377917067 NKPRPPPLSPLGGPVPSALPNGPPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 NKPRPPPLSPLGGPVPSALPNGPPSPR 27 2 Q15642 Q15642 TRIP10 Cdc42-interacting protein 4 1 NKPRPPPLSPLGGPVPSALPNGPPS(1)PR 99.863 5.795399999999999e-10 12947000.0 61143.0 43994.0 41359.0 42223.0 44354.0 42629.0 43649.0 43511.0 33754.0 26540.0 True False 60271.08960774706 43892.13459598331 37958.62267035688 45328.220271798935 41745.184923319095 40805.85704305257 45908.93164380274 45532.6799047149 29952.269074622407 31127.403637672927 1.93627102052296 1.410080169451122 1.2194599688493215 1.456215905426144 1.3411071931741734 1.3109303145883324 1.4748718581925027 1.462784382363569 0.9622475881146645 1.0 14.92589762499555 -1.5228787452803376 0.10376662340577553 0.8528844422186334 3.1261904108136824 0.4875593540447756 0.18637807589094657 126.05316449661902 0.9253577913194158 2.195823529920808 40.8556440478307 0.029999999999999995 1.5228787452803376 2.273305968595049 NKPRS(ph)PVVELSK ddPTM_PC-9_Lapatinib_30min_R1 2 NKPRSPVVELSK 12 2 P25098 P25098 ADRBK1 Beta-adrenergic receptor kinase 1 1 NKPRS(1)PVVELSK;NKPRS(1)PVVELSK 67.252 0.011933 34522000.0 289250.0 259310.0 273020.0 258120.0 278440.0 268650.0 253230.0 233190.0 302920.0 260250.0 True False 285125.241958046 258709.58362695843 250573.3494876769 277103.00586307846 262062.7066341026 257160.46575373755 266341.01033609407 244024.85870194805 268801.95971098606 305233.8657386734 0.9341206005042589 0.847578243000248 0.8209225043927654 0.9078383396039047 0.8585636656008154 0.8425030595193064 0.8725801433977265 0.7994684931549189 0.8806426477628186 1.0 18.2195555126995 -8.555362526652388 22.69004503329831 1.0000000007316376 0.8587756951709813 0.559721863069077 0.03689850329629201 2831.4005711641325 1977741.2089426476 0.034652095152012896 0.008947132517796228 2.7837964286808197e-09 8.555362526652388 -0.14122430556065635 NKPY(ph)ISWPSSGGSEPSVTVPLR ddPTM_PC-9_AZD4547_30min_R2 1 NKPYISWPSSGGSEPSVTVPLR 22 1 Q9Y5S2 Q9Y5S2 CDC42BPB Serine/threonine-protein kinase MRCK beta 1 NKPY(0.496)IS(0.496)WPS(0.007)S(0.001)GGSEPSVTVPLR 61.303999999999995 0.030052999999999996 8266400.0 8564.3 11398.0 12918.0 26421.0 20608.0 20434.0 15889.0 19937.0 14828.0 18570.0 True False 11287.569251493676 15082.18059996171 12746.69887952874 20330.04665038083 17746.93491997333 19156.258749732442 17303.09021892841 16856.194756683064 15611.777808038023 17919.869952268098 0.6298912481820227 0.8416456503387054 0.7113164835169691 1.1344974435937623 0.9903495375381962 1.068995411281311 0.9655812383135278 0.9406426944828131 0.8711992804424374 1.0 14.129272547084549 -5.745166766201195 24.99999116837203 0.9949735735794013 0.7390204697922101 0.6912320976216679 0.08205931643605785 143.36979970851183 220260.58444412105 0.022478444843031638 0.03878551355425686 1.798180293231495e-06 5.745166766201195 -0.25595310378719116 NKPYIS(ph)WPSSGGSEPSVTVPLR ddPTM_PC-9_AZD4547_30min_R2 1 NKPYISWPSSGGSEPSVTVPLR 22 1 Q9Y5S2 Q9Y5S2 CDC42BPB Serine/threonine-protein kinase MRCK beta 1 NKPY(0.049)IS(0.902)WPS(0.036)S(0.013)GGSEPSVTVPLR 81.904 0.00018351 6119300.0 12761.0 15904.0 20822.0 36445.0 31393.0 30354.0 16054.0 29307.0 14457.0 31037.0 True False 16818.732554710918 21044.656980329117 20545.886675146896 28043.16831963702 27034.623832624355 28455.95958154932 17482.77489928106 24778.27655786279 15221.167505449537 29950.40407692758 0.561552776099849 0.7026501854958597 0.6859969776158882 0.9363201994740429 0.9026463804356679 0.9501026933880496 0.5837241746180308 0.827310259127717 0.5082124256605682 1.0 14.870287846865581 -14.025137225913586 0.022934784339660234 1.8868661496446235 3.5110244694436814e-06 0.11404081477634631 0.16083632755702074 6867.407643161816 12.846232172467401 725.0722277925956 381.85307601319477 9.437626243932464e-15 14.025137225913586 -1.8868626386201541 NKPYIS(ph)WPSSGGSEPSVTVPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NKPYISWPSSGGSEPSVTVPLR 22 1 Q9Y5S2 Q9Y5S2 CDC42BPB Serine/threonine-protein kinase MRCK beta 1 NKPY(0.012)IS(0.986)WPS(0.002)SGGSEPSVTVPLR;NKPY(0.01)IS(0.987)WPS(0.002)S(0.001)GGSEPSVTVPLR 69.952 0.00090697 10419500.0 19006.8 19040.7 17910.0 24752.1 34819.0 38608.0 41716.0 38071.0 33422.0 36712.0 True False 22224.275838588266 20930.93486039755 18337.04232405324 23365.320084390936 27996.466900282896 36583.328514500354 37764.35848231425 37071.67658955881 33910.73352178803 43367.594987967925 0.5124627234863787 0.4826399726847825 0.42282820454168 0.538773710898045 0.6455618972656968 0.8435636913840894 0.870796697229619 0.8548243590598953 0.781937147568279 1.0 15.404329818251071 -6.536981480565367 1.7930442159582014 0.8690725805128244 0.47554763677273637 0.9121950399655421 0.05610112550513127 0.09421854859335753 0.613769835258803 0.021034472451618838 0.022686982517827973 2.904146492106089e-07 6.536981480565367 -0.39352494374008806 NKPYIS(ph)WPSSGGSEPSVTVPLR ddPTM_PC-9_Lapatinib_30min_R1 1 NKPYISWPSSGGSEPSVTVPLR 22 1 Q9Y5S2 Q9Y5S2 CDC42BPB Serine/threonine-protein kinase MRCK beta 1 NKPY(0.167)IS(0.819)WPS(0.01)S(0.004)GGSEPSVTVPLR 72.499 0.00062955 4377500.0 9959.8 10770.0 10256.0 9906.3 14385.0 16283.0 9523.0 11925.0 14302.0 11306.0 True False 9817.771425596373 10745.062726706821 9412.791269304877 10634.842348448055 13538.902581998134 15586.614047526913 10016.05434360314 12479.079034352817 12691.158153263299 13260.227035701957 0.740392408000475 0.8103226813369572 0.7098514410018615 0.8020105779346544 1.0210158955458204 1.1754409638357903 0.7553456148703807 0.9410909029501554 0.957084529480039 1.0 13.69481785639341 -6.150247874981991 4.9075212534012005 0.9705221912105607 0.7593274097627811 0.5187315028065188 0.09930229927467181 0.20317489858692994 7.472770208959591 0.031044707780682357 0.040588847952935235 7.075418373230598e-07 6.150247874981991 -0.2111947814477796 NKQDDDLNCEPLS(ph)PHNITPEPVSK ddPTM_PC-9_AZD4547_30min_R2 3 NKQDDDLNCEPLSPHNITPEPVSK 24 1 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4;A8MV73;F8WE35;F5H8I0;F5H2W9;F5H2H9;F5GZ10;F5H502;F5H1K9 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 NKQDDDLNCEPLS(0.994)PHNIT(0.006)PEPVSK;NKQDDDLNCEPLS(0.997)PHNIT(0.003)PEPVSK;NKQDDDLNCEPLS(0.999)PHNIT(0.001)PEPVSK 84.025 1.1352e-05 189718000.0 312961.0 313054.0 379825.0 487500.0 435137.0 429913.0 368246.0 425842.0 361133.0 416161.0 True False 412476.0880068079 414242.5833953689 374788.2723267539 375114.40679991926 374725.73856135685 403030.47214807355 401019.18061297166 360037.9037756648 380221.75311236834 401591.33005954896 1.027104066080423 1.0315028049384034 0.9332578775323146 0.934069982896036 0.9331021626034396 1.0035835985012704 0.9985752943259695 0.8965280792348717 0.946787753251516 1.0 18.615368597771536 -5.2527354993183915 24.56199502818608 0.9536990485577663 1.0293034508661947 0.43508893953493033 0.03346559184347292 468.22214547385806 1321294.453986686 0.00895686210264249 0.022900508920316406 5.588104264102931e-06 5.2527354993183915 0.07560440230842835 NKQDDDLNCEPLS(ph)PHNITPEPVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NKQDDDLNCEPLSPHNITPEPVSK 24 1 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4;A8MV73;F8WE35;F5H8I0;F5H2W9;F5H2H9;F5GZ10;F5H502;F5H1K9 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 NKQDDDLNCEPLS(0.964)PHNIT(0.036)PEPVSK;NKQDDDLNCEPLS(0.993)PHNIT(0.006)PEPVSK 89.39200000000001 6.9147e-06 21265900.0 47779.0 41841.0 40007.0 55483.0 57832.0 48507.0 51564.0 52143.0 48417.0 39706.0 True False 55867.04102173481 45994.69796246427 40960.9186073924 52374.467388312965 46500.23475048565 45963.20752830682 46679.48462896855 50774.30150007525 49125.007029035136 46904.38348747695 1.1910835804216637 0.9806055328441624 0.8732855132469356 1.1166220189696443 0.9913835614724751 0.9799341577654161 0.9952051633176577 1.0825065319029623 1.0473436249759271 1.0 15.51743513683438 -7.744330670087553 24.96904631854803 1.0486938320094488 1.0125457465247698 0.01426603305090357 0.08273420319813246 941.7581682408431 1374438.1617740465 0.03900246712211685 0.022453114149109298 1.8016454528315813e-08 7.744330670087553 -0.03614808548467896 NKQDDDLNCEPLS(ph)PHNITPEPVSK ddPTM_PC-9_Lapatinib_30min_R1 5 NKQDDDLNCEPLSPHNITPEPVSK 24 1 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4;A8MV73;F8WE35;F5H8I0;F5H2W9;F5H2H9;F5GZ10;F5H502;F5H1K9 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 NKQDDDLNCEPLS(0.945)PHNIT(0.053)PEPVS(0.002)K;NKQDDDLNCEPLS(0.994)PHNIT(0.006)PEPVSK;NKQDDDLNCEPLS(0.994)PHNIT(0.006)PEPVSK;NKQDDDLNCEPLS(0.976)PHNIT(0.023)PEPVSK;NKQDDDLNCEPLS(0.999)PHNIT(0.001)PEPVSK 72.935 0.00020819 286219600.0 207698.0 283336.0 335421.0 343588.0 370467.0 359347.0 360055.0 348531.0 353537.0 297448.0 True False 204736.18843285175 282679.95290011144 307843.9801425023 368856.607695969 348676.85942614585 343978.5664887703 378696.8861373547 364725.0226349699 313717.940150346 348861.4904754534 0.5868695571810538 0.81029279704921 0.8824246543318682 1.0573153465384353 0.9994707611635325 0.9860032588290892 1.085522181371293 1.0454722937114571 0.8992621676952328 1.0 18.412294827009596 -4.770433881951614 1.0967105445748484 1.0152396874455936 0.37128394590760616 0.8588924890132201 0.05333496331832729 0.5980883658949739 0.5804496717902559 0.016936829004324798 0.4528390635294059 1.6965478691746043e-05 4.770433881951614 -0.6439557415379874 NKS(ph)NEDQSMGNWQIK ddPTM_PC-9_AZD4547_30min_R2 1 NKSNEDQSMGNWQIK 15 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 NKS(0.997)NEDQS(0.003)MGNWQIK 67.252 0.014254 30296000.0 49694.0 57623.0 63175.0 56169.0 63520.0 75436.0 54700.0 57302.0 65538.0 67345.0 True False 65495.65830058808 76248.50787081884 62337.25822218828 43220.10485239929 54701.344435010964 70718.97499485264 59568.1940320589 48447.29256896489 69002.20488152115 64987.27204822271 1.0078228587897664 1.1732837133745193 0.9592225717049943 0.6650549175279821 0.8417239670318944 1.0881973156586235 0.9166132406336017 0.7454889402499523 1.0617802949217383 1.0 15.987869569214036 -5.512086897139458 24.60704361981838 0.8912645084260402 1.0844782997084106 0.24255240588373517 0.12998544072818888 538.5561533650779 1227986.5788471492 0.035234797339682614 0.06669066466132402 3.075481386075029e-06 5.512086897139458 0.19321379128237037 NKS(ph)NEDQSMGNWQIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NKSNEDQSMGNWQIK 15 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 NKS(0.998)NEDQS(0.002)MGNWQIK;NKS(0.898)NEDQS(0.102)MGNWQIK;NKS(0.661)NEDQS(0.339)MGNWQIK 77.357 0.016614 5564200.0 60380.0 67400.0 56150.0 68013.0 70839.0 53771.0 70072.0 54543.0 53320.0 44567.0 True False 70601.1414406401 74091.02656891801 57488.82895006086 64202.45211112102 56958.60647201636 50951.15410156444 63434.272882652294 53111.30404308545 54099.70412847045 52646.6443078221 1.3410378262257139 1.4073266690220891 1.0919751810566836 1.2194975188871058 1.0819038368140323 0.9677949045271677 1.2049062901664827 1.008826008596987 1.0276002362496721 1.0 15.68405395648419 -5.275633878155203 0.7991568005811204 1.0468483324377234 1.4722663047901372 0.6664765495230072 0.08307938867679025 0.84516317580265 0.6633036926966092 0.03375904297288837 0.2819449356679212 5.301101525851802e-06 5.275633878155203 0.42541797235241385 NKS(ph)NEDQSMGNWQIK ddPTM_PC-9_Lapatinib_30min_R1 3 NKSNEDQSMGNWQIK 15 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 NKS(0.941)NEDQS(0.059)MGNWQIK;NKS(0.999)NEDQS(0.001)MGNWQIK;NKS(0.909)NEDQS(0.091)MGNWQIK 89.911 0.0062424 82164100.0 112908.5 121614.0 115959.0 109695.0 140056.0 119825.0 114758.0 127919.0 119680.0 98123.0 True False 111298.40408511704 121332.4102549418 106425.29863468438 117762.33623179283 131818.18144069024 114700.36407571788 120699.60772479353 133862.58373126885 106200.37811372889 115083.42980932114 0.9671105933280281 1.054299567331061 0.9247664829855854 1.0232779508475747 1.1454140848869077 0.9966714084361411 1.0488009257699193 1.1631786083631885 0.9228120702492935 1.0 16.812320597630155 -5.997492912604666 24.989208255051203 1.0549079225060756 0.9867394868001976 0.12755714881584757 0.07252392646879162 146.31471520335572 1458336.438852966 0.01949475636085256 0.028735199377779654 1.0057894766790376e-06 5.997492912604666 -0.06816843570587794 NKS(ph)PPADPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NKSPPADPPR 10 1 O60566-3;O60566;O60566-2 O60566-3 BUB1B Mitotic checkpoint serine/threonine-protein kinase BUB1 beta 1 NKS(1)PPADPPR 56.434 0.040402 8614600.0 60339.0 59787.0 50907.0 65824.0 70519.0 54680.0 61545.0 71110.0 62546.0 44433.0 True False 70553.20095042718 65722.25824148211 52120.81594587261 62136.0946842874 56701.308174877224 51812.484541361395 55715.01205278625 69243.43784727297 63460.61692459325 52488.35116856552 1.3441687418194312 1.2521303637528278 0.9929977754204438 1.1838073267864389 1.0802646094327075 0.9871234928863818 1.0614738472896275 1.319215336463871 1.2090419209548129 1.0 15.679709658022206 -5.0446413483922035 5.863017193233791 1.1119312314589618 1.3245533368167794 0.379255717397332 0.10190290428517866 0.191981519008492 17.13126756389962 0.027587482979036803 0.08090031299400391 9.023159858682621e-06 5.0446413483922035 0.21262210535781767 NKS(ph)TESLQANVQR ddPTM_PC-9_AZD4547_30min_R2 1 NKSTESLQANVQR 13 1 P26373;J3QSB4 P26373 RPL13 60S ribosomal protein L13 1 NKS(0.969)T(0.03)ESLQANVQR 92.26899999999999 0.0022183000000000003 11449000.0 20803.0 12354.0 27838.0 31728.0 34641.0 25514.0 27256.0 24125.0 20918.0 22991.0 True False 27417.921270719482 16347.188904362785 27468.849930973938 24413.59979271351 29831.69509718537 23918.605546670897 29681.73119813159 20397.03558734908 22023.682775056615 22186.092087915757 1.23581571563265 0.7368214663305538 1.2381112375322545 1.1004010844258159 1.3446124256120795 1.0780900688543882 1.3378530603998768 0.919361350639073 0.9926796791334153 1.0 14.437367949657878 -7.80366754595214 24.999127940135015 0.9670151508254355 1.1428140161672549 0.20298096500466523 0.16472081426639507 253.32347360799022 149964.54228139372 0.08945084159531838 0.042971314699644735 1.5715653831556794e-08 7.80366754595214 0.17579886534181932 NKS(ph)TESLQANVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NKSTESLQANVQR 13 1 P26373;J3QSB4 P26373 RPL13 60S ribosomal protein L13 1 NKS(0.878)T(0.109)ES(0.013)LQANVQR 128.71 0.0013321 0.0 5340.6 6346.4 6259.6 8207.8 7687.2 7747.1 8279.7 9341.4 5894.6 6306.8 True False 6244.658098341884 6976.428650103568 6408.852603665193 7747.943576046633 6180.948343026929 7340.828438009892 7495.38687616304 9096.198148031435 5980.79737351241 7450.17291539867 0.8381896862333058 0.9364116416256694 0.8602287056208877 1.0399682885255597 0.8296382397046925 0.9853232295907153 1.0060688471633883 1.2209378562517141 0.8027729613027872 1.0 12.863058194974222 -6.962633871703978 8.454249807079156 1.0216622269622868 0.9080413204241603 0.17486439621215843 0.10948124725608696 0.41623920273259873 84.68891133780245 0.036890750074341956 0.03240595262349124 1.089848493724739e-07 6.962633871703978 -0.11362090653812651 NKS(ph)TESLQANVQR ddPTM_PC-9_Lapatinib_30min_R1 1 NKSTESLQANVQR 13 1 P26373;J3QSB4 P26373 RPL13 60S ribosomal protein L13 1 NKS(0.832)T(0.162)ES(0.006)LQANVQR 77.24 0.0077102 9714500.0 21513.0 18181.0 17835.0 17942.0 17565.0 21855.0 19467.0 20318.0 21147.0 15749.0 True False 21206.220674998975 18138.903011537303 16368.675145090916 19261.51453275743 16531.861234118685 20920.312596493306 20474.90600723745 21262.048454505708 18765.202172217818 18471.193665776584 1.1480698572442476 0.982010331316327 0.8861731104806068 1.0427866699511223 0.8950077365464966 1.1325912648111338 1.1084776857260363 1.1510922812692943 1.0159171362588209 1.0 14.17298948030681 -6.780463467424483 24.99993629974823 1.0927378231905072 0.9873951506796188 0.22818236495786703 0.08212061417417957 324.11626119482986 425924.78136972577 0.02844283467776306 0.02512347412679466 1.657816785476914e-07 6.780463467424483 -0.10534267251088836 NKSNEDQS(ph)MGNWQIK ddPTM_PC-9_AZD4547_30min_R2 1 NKSNEDQSMGNWQIK 15 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 NKS(0.088)NEDQS(0.912)MGNWQIK 66.939 0.014555000000000002 38468000.0 63065.0 57364.0 58471.0 65253.0 76638.0 66098.0 67559.0 57668.0 58756.0 57796.0 True False 83118.35816651073 75905.79118583984 57695.63633572732 50209.928998800235 65998.13656817342 61964.881611031364 73571.62012087504 48756.735678808174 61861.72220724865 55772.57963173327 1.490308655531837 1.360987633834517 1.0344803255774075 0.9002619088149901 1.1833438044996227 1.1110277132631465 1.3191360451079897 0.8742062138912927 1.1091780695051587 1.0 15.767268380595063 -5.13465687278422 3.668828795434489 1.0709657393563208 1.4661808187795649 0.5804125497385397 0.12394588879947349 0.16860695746823998 3.971027063192586 0.03283920314808534 0.10621617838777028 7.334037516459883e-06 5.13465687278422 0.3952150794232441 NKTS(ph)TTSSMVASAEQPR ddPTM_PC-9_AZD4547_30min_R2 1 NKTSTTSSMVASAEQPR 17 1 E7EMN6;Q6NXS1;P41236;E7EUI7 E7EMN6 PPP1R2;PPP1R2P3 Protein phosphatase inhibitor 2-like protein 3;Protein phosphatase inhibitor 2 1 NKT(0.057)S(0.893)T(0.028)T(0.007)S(0.007)S(0.007)MVASAEQPR 94.882 0.029513 0.0 11692.0 13956.0 14722.0 23937.0 22750.0 16335.0 14489.0 19578.0 15010.0 16875.0 True False 15409.812791292234 18467.00407554533 14526.776660816076 18418.69447296341 19591.555193584678 15313.569867714554 15778.492931087774 16552.669957683756 15803.397956477667 16284.211386350256 0.9463039029454653 1.1340435000140525 0.8920773819598475 1.1310768471356445 1.2031012573324062 0.940393704330729 0.9689442464689211 1.0164858196055184 0.9704736435517156 1.0 13.991186233974684 NKTS(ph)TTSSMVASAEQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NKTSTTSSMVASAEQPR 17 1 E7EMN6;Q6NXS1;P41236;E7EUI7 E7EMN6 PPP1R2;PPP1R2P3 Protein phosphatase inhibitor 2-like protein 3;Protein phosphatase inhibitor 2 1 NKT(0.003)S(0.43)T(0.141)T(0.141)S(0.141)S(0.141)MVAS(0.001)AEQPR 86.488 0.042497 0.0 29392.0 22451.0 17059.0 25615.0 18753.0 17706.0 16129.0 20380.0 11826.0 12064.0 True False 34367.48508153856 24679.786906510028 17465.751256617772 24179.874594950477 15078.484269536884 16777.466190368403 14601.144356152234 19845.046594394913 11998.93287740606 14251.107701428538 2.4115658797591952 1.7317802534069764 1.225571486970588 1.6967014144820949 1.0580570005814642 1.1772745348550429 1.0245620664763209 1.3925266028552739 0.8419649285369782 1.0 13.798786440107461 -1.5228787453186918 0.544557242825503 1.0943023399191352 56.96904905949967 0.7963791442326157 0.20237588942432194 55.53329877459389 0.5174211889748485 0.09743102331943584 3621.502561280356 0.02999999999735058 1.5228787453186918 55.874746719580536 up NKTS(ph)TTSSMVASAEQPR ddPTM_PC-9_Lapatinib_30min_R1 1 NKTSTTSSMVASAEQPR 17 1 E7EMN6;Q6NXS1;P41236;E7EUI7 E7EMN6 PPP1R2;PPP1R2P3 Protein phosphatase inhibitor 2-like protein 3;Protein phosphatase inhibitor 2 1 NKT(0.097)S(0.841)T(0.057)T(0.002)S(0.001)S(0.002)MVASAEQPR 89.87700000000001 0.037254 0.0 12367.0 9700.6 9421.6 7580.4 7021.3 9608.3 8028.9 9993.9 9284.9 9411.2 True False 12190.644312169952 9678.138856703084 8646.992416427725 8137.887903473099 6608.320938406918 9197.37540704126 8444.597156290583 10458.25307852567 8239.136787668469 11037.91338036425 1.1044337722251325 0.8768087339695817 0.783390131672004 0.7372668749104234 0.5986929513473718 0.8332530877985334 0.7650537620011575 0.947484612184966 0.7464397032074351 1.0 13.430179848737694 -4.776493177892032 2.426877476724368 0.7902901392436544 1.1794127844084372 0.420870030036694 0.10622283360547619 0.5296473595987603 3.8260283649108127 0.0276936929809102 0.4412325842551839 1.6730419171445994e-05 4.776493177892032 0.3891226451647828 NLAANDLSPS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 NLAANDLSPSR 11 0 Q96CB9-4;Q96CB9 Q96CB9-4 NSUN4 5-methylcytosine rRNA methyltransferase NSUN4 1 NLAANDLS(0.025)PS(0.975)R 71.806 0.028810000000000002 4968000.0 24121.0 20836.0 42859.0 61394.0 55274.0 43309.0 32580.0 64601.0 32357.0 43534.0 True False 31790.97625203216 27570.82952981245 42290.661656426884 47240.56182784455 47600.15919869009 40600.881383584325 35479.55688417694 54618.399833299 34067.324961875274 42009.88791071832 0.7567498470740046 0.6562938132186277 1.0066835157071898 1.1245105420952977 1.1330703690486517 0.9664601217187608 0.8445525243861639 1.3001320058119883 0.8109358690572323 1.0 15.358441316031662 -5.292829884809719 7.249073143428392 1.0337262642805087 0.7063865675281592 0.4622160056092439 0.1363345760017377 0.1581694926822593 30.455809328100685 0.03433932640773461 0.07405235380083224 5.095304174329468e-06 5.292829884809719 -0.32733969675234953 NLAANDLSPS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 NLAANDLSPSR 11 0 Q96CB9-4;Q96CB9 Q96CB9-4 NSUN4 5-methylcytosine rRNA methyltransferase NSUN4 1 NLAANDLS(0.135)PS(0.865)R 75.102 0.022099 3006500.0 42193.0 33709.0 30659.0 28656.0 30919.0 26143.0 25262.0 19041.0 36349.0 17796.0 True False 41591.320082751445 33630.948881574775 28138.335367162468 30763.45783361371 29100.40520909283 25024.924832309538 26569.9427520847 19925.714372588012 32254.992848060956 20872.01488832054 1.9926835193101031 1.6112938334666393 1.348136991934975 1.4739093469518447 1.394230761371136 1.198970246342286 1.2729936661243269 0.954661755427261 1.545370344964158 1.0 14.34928225791378 -1.5228787452803376 0.4269337392219617 1.1826927678838417 16.37346689160603 0.6801201545603475 0.16350921031496155 45.49136088009026 0.5752193185569691 0.10408508038946909 593.1282216336239 0.029999999999999995 1.5228787452803376 15.190774123722187 NLANTVTEEILEK ddPTM_PC-9_Lapatinib_30min_R1 1 NLANTVTEEILEK 13 0 O60506-2;O60506;O60506-4;O60506-3;B7Z645;O60506-5 O60506-2 SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0 136.3 0.00025207 1348100.0 8217.0 7203.3 6882.6 6492.1 6349.7 7714.6 5963.2 5503.2 6906.1 7243.3 False True 8099.824073186748 7186.6212014194325 6316.739195604302 6969.5506910107315 5976.223129990516 7384.664541610949 6271.945317838313 5758.898762419323 6128.262293542984 8495.294753909426 0.9534482684617049 0.8459531316570554 0.7435573901302741 0.8204012801090196 0.7034744883031085 0.86926525276979 0.73828460336259 0.6778927546650635 0.7213713556816655 1.0 13.052448288884559 -4.881510603170475 2.561143557790305 0.772592125291006 0.9721976386026975 0.23844283130383392 0.09057899020257151 0.5058768779678604 5.088328666953188 0.022442469172015173 0.2020677428889027 1.3136794214765735e-05 4.881510603170475 0.19960551331169152 NLAS(ph)PEGTLATLGLK ddPTM_PC-9_AZD4547_30min_R2 1 NLASPEGTLATLGLK 15 0 Q8TDJ6-3;Q8TDJ6;Q8TDJ6-2 Q8TDJ6-3 DMXL2 DmX-like protein 2 1 NLAS(0.925)PEGT(0.016)LAT(0.059)LGLK 66.059 0.032642000000000004 40308000.0 10557.0 13934.0 16989.0 19382.0 15217.0 15576.0 13667.0 15687.0 10901.0 16127.0 True False 13913.906400758817 18437.89300577878 16763.71475958459 14913.779348914934 13104.382214539703 14602.030257699545 14883.336523512784 13262.934601398763 11477.204605167428 15562.398638676768 0.8940720979977339 1.1847719258363958 1.0771935065281149 0.9583213806032548 0.8420541408039612 0.9382891800117208 0.9563652023746306 0.8522423123410285 0.7374958624079627 1.0 13.925776820170837 -5.936222022571046 3.7385197961784127 0.8867452085458051 1.0643622527258612 0.3731124476780989 0.09474300853184286 0.22486304595405915 6.375747777805853 0.027505129078540958 0.04175851926457084 1.1581851106004178e-06 5.936222022571046 0.17761704418005608 NLAS(ph)PEGTLATLGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLASPEGTLATLGLK 15 0 Q8TDJ6-3;Q8TDJ6;Q8TDJ6-2 Q8TDJ6-3 DMXL2 DmX-like protein 2 1 NLAS(0.494)PEGT(0.494)LAT(0.013)LGLK 91.81200000000001 0.0037879 4742200.0 11460.0 10180.0 12073.0 13329.0 12219.0 11833.0 12065.0 12821.0 9676.5 11662.0 True False 13399.951654682625 11190.603122723795 12360.866107107471 12582.219343201043 9824.774664825427 11212.456649194028 10922.11585696428 12484.462334972393 9818.000506360542 13776.228283658798 0.9726865277470389 0.8123125497272689 0.8972605456727069 0.913328313390823 0.7131686890293085 0.8138988711804459 0.7928233789447265 0.9062322486178105 0.7126769609361469 1.0 13.74989333426195 -2.679948168843512 1.6736095831887234 0.8333085675818604 167.56927336133884 0.15924844325711418 0.08718653446140869 2941.1737998432986 8.703495348964177 0.021790800513294385 1882330.8449881102 0.002089545494135144 2.679948168843512 166.73596479375698 NLASPEGT(ph)LATLGLK ddPTM_PC-9_Lapatinib_30min_R1 1 NLASPEGTLATLGLK 15 0 Q8TDJ6-3;Q8TDJ6;Q8TDJ6-2 Q8TDJ6-3 DMXL2 DmX-like protein 2 1 NLAS(0.318)PEGT(0.675)LAT(0.007)LGLK 77.068 0.032521 30758000.0 9044.6 7396.4 12708.0 10051.0 10333.0 7931.5 7106.9 8174.1 11548.0 9209.5 True False 8915.6223454235 7379.274090233462 11663.197294298592 10790.184069153102 9725.233255459627 7592.288234229545 7474.860507671236 8553.898527019152 10247.342634168976 10801.34980411261 0.8254174253322377 0.6831807342656199 1.0797907211428182 0.9989662648500416 0.9003720305175885 0.7029018013414198 0.6920302224473079 0.7919286646713597 0.9487094502084641 1.0 13.398923991384258 -6.599124648220602 24.998903011264908 0.805218197851537 0.901526661067915 0.053181057192793424 0.13293854825646506 91.46333285296177 29984.518492587147 0.04628962433528104 0.04628962815941094 2.516954425100677e-07 6.599124648220602 0.09630846321637798 NLATS(ph)ADTPPSTVPGTGK ddPTM_PC-9_AZD4547_30min_R2 2 NLATSADTPPSTVPGTGK 18 0 Q96Q15;J3KRA9;Q96Q15-4;Q96Q15-3;Q96Q15-2 Q96Q15 SMG1 Serine/threonine-protein kinase SMG1 1 NLAT(0.073)S(0.669)ADT(0.176)PPS(0.008)T(0.073)VPGTGK;NLAT(0.136)S(0.793)ADT(0.067)PPS(0.001)T(0.001)VPGT(0.002)GK 210.47 2.3685999999999993e-67 0.0 46761.0 43982.0 55345.0 75355.0 59941.0 54491.0 43060.0 52969.0 46750.0 50551.0 True False 61630.02531077796 58198.321385112875 54611.089138219424 57983.06897314443 51619.22680697401 51083.66915590047 46892.25658172685 44783.85815653034 49221.10955798342 48781.22487652689 1.2633964289903226 1.1930475614833815 1.1195104115661068 1.1886349537123941 1.058178160503976 1.0471993945457794 0.9612767350639242 0.9180552204231336 1.0090174997157195 1.0 15.574038363618458 -6.389454802358112 0.8417860974806172 0.9601337447402484 1.221489562237953 0.8516311073985723 0.04093047997310891 0.2260879347169262 0.3505976156514903 0.022953985902626248 0.032889396387386326 4.078920094616191e-07 6.389454802358112 0.26135581749770453 NLATS(ph)ADTPPSTVPGTGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NLATSADTPPSTVPGTGK 18 0 Q96Q15;J3KRA9;Q96Q15-4;Q96Q15-3;Q96Q15-2 Q96Q15 SMG1 Serine/threonine-protein kinase SMG1 1 NLAT(0.125)S(0.482)ADT(0.26)PPS(0.098)T(0.016)VPGT(0.02)GK;NLAT(0.085)S(0.914)ADT(0.001)PPSTVPGTGK 181.86 3.9693e-09 4642800.0 54937.0 57470.0 48286.0 61259.0 62549.0 52155.0 52456.0 53701.0 46843.0 41162.0 True False 64236.74904479051 63175.24179400161 49437.32136567475 57826.85683435767 50292.97246175345 49419.89998636982 47486.987931447824 52291.40565091276 47527.99025675054 48624.34476178731 1.3210820497322693 1.299251272248495 1.016719538491886 1.1892572972994053 1.034316713328289 1.0163612533696849 0.9766093129704586 1.0754161502245538 0.9774525598152971 1.0 15.56939118871688 -4.271237271860844 0.5537133956655393 1.005571242666602 1.8132394774693001 0.7528853802626067 0.061841939180387905 3.1422133219569504 0.4846868597007308 0.03168530875296505 1.8445818308813762 5.3550401104024486e-05 4.271237271860844 0.8076682348026982 NLATS(ph)ADTPPSTVPGTGK ddPTM_PC-9_Lapatinib_30min_R1 4 NLATSADTPPSTVPGTGK 18 0 Q96Q15;J3KRA9;Q96Q15-4;Q96Q15-3;Q96Q15-2 Q96Q15 SMG1 Serine/threonine-protein kinase SMG1 1 NLAT(0.132)S(0.546)ADT(0.254)PPS(0.062)T(0.007)VPGTGK;NLAT(0.05)S(0.948)ADT(0.001)PPSTVPGTGK;NLAT(0.012)S(0.892)ADT(0.092)PPS(0.002)T(0.001)VPGTGK;NLAT(0.006)S(0.968)ADT(0.025)PPS(0.001)TVPGTGK 200.45 5.746e-15 21938400.0 165832.0 140820.0 148146.0 129095.0 127212.0 126509.0 110464.0 105574.0 132948.0 84113.0 True False 163467.20527013583 140493.939941955 135966.00774009747 138589.07694829578 119729.64026841495 121098.5049768827 116183.2854154968 110479.35345683535 117973.99623549503 98651.81997647262 1.6570115514252142 1.4241393618025626 1.378241250617818 1.4048304124682927 1.2136587069247091 1.2275344236504038 1.177710512012908 1.1198916906265233 1.1958623395253178 1.0 16.590058046279445 -1.5228787452851689 0.20806855835349167 1.017053466623807 4.015450740855766 0.9169087665798079 0.05131259422161902 13.325614680387362 0.1649673791189017 0.08615175594186869 13.18340925735213 0.029999999999666266 1.5228787452851689 2.9983972742319587 NLATSADT(ph)PPSTVPGTGK ddPTM_PC-9_AZD4547_30min_R2 1 NLATSADTPPSTVPGTGK 18 0 Q96Q15;J3KRA9;Q96Q15-4;Q96Q15-3;Q96Q15-2 Q96Q15 SMG1 Serine/threonine-protein kinase SMG1 1 NLATSADT(0.846)PPS(0.094)T(0.058)VPGT(0.002)GK 188.1 2.1511000000000002e-10 4660200.0 24936.0 23183.0 30220.0 38768.0 32393.0 24624.0 20885.0 29332.0 19178.0 27070.0 True False 32865.129298979045 30676.451381725965 29819.26305460278 29830.636559629238 27895.79109388082 23084.257387364753 22743.724540393974 24799.413382305636 20191.70992733702 26122.287539466724 1.2581260063585524 1.1743401620313154 1.1415257185861114 1.1419611132662013 1.067892352525965 0.8836996894888329 0.8706635858759205 0.9493584106995825 0.7729686727025907 1.0 14.67299361936409 -6.526613701331273 1.7940258078573454 0.8861708838058571 1.1846917426203398 0.8186687664970427 0.06307303021803062 0.13777000845766296 0.8970033253651395 0.023234233858723294 0.02525028568595919 2.9743104616674327e-07 6.526613701331273 0.29852085881448276 NLDDGIDDER ddPTM_PC-9_AZD4547_30min_R2 2 NLDDGIDDER 10 0 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YAR2;Q9H361;H0YAP2 A0A087WTT1 PABPC1;PABPC3 Polyadenylate-binding protein;Polyadenylate-binding protein 1;Polyadenylate-binding protein 3 0 ; 175.33 0.00057269 47732000.0 85768.0 79686.0 122952.0 139702.0 129302.0 113276.0 88088.0 148488.0 97347.0 101532.0 False True 113040.4399147754 105442.94115533853 121321.57614459025 107495.8622743841 111350.64921498389 106192.83381299241 95927.66135093248 125542.59151478946 102492.56368216066 97977.39558393558 1.1537399952414082 1.0761966117481387 1.2382608807013664 1.0971496193965904 1.1364932549119626 1.0838503430316109 0.9790795190994118 1.2813424031795093 1.0460837734185027 1.0 16.580161322241054 -6.467818235868381 2.1509716898699978 1.0908879986111129 1.1448003245817955 0.10253751734709737 0.08668859969104986 0.9512880878409927 8.756501315890963 0.0306432045098215 0.03428317857217936 3.4055068966672375e-07 6.467818235868381 0.05391232597068263 NLDDGIDDER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLDDGIDDER 10 0 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YAR2;Q9H361;H0YAP2 A0A087WTT1 PABPC1;PABPC3 Polyadenylate-binding protein;Polyadenylate-binding protein 1;Polyadenylate-binding protein 3 0 152.69 0.00078844 17927000.0 27338.0 37427.0 36474.0 32828.0 32746.0 24444.0 36697.0 26869.0 27539.0 19966.0 False True 31965.783449887742 41142.50521357401 37343.67848841531 30988.753589812004 26329.656369127875 23162.11360879733 33220.794496727554 26163.717220058734 27941.70577633059 23585.677749230967 1.355304850246672 1.7443851158746329 1.5833201354424906 1.3138801402822704 1.1163408848824103 0.9820414683462955 1.4085155766961477 1.1093052952829319 1.1846895422473775 1.0 14.525623437758732 -5.925269206356506 3.098663341606033 1.1473142302947918 1.580754937326558 0.6448559380835854 0.14142433135560187 0.15313603820678665 2.97163630400314 0.0413764989966015 0.06435535936266598 1.187765738203002e-06 5.925269206356506 0.43344070703176607 NLDDGIDDER ddPTM_PC-9_Lapatinib_30min_R1 1 NLDDGIDDER 10 0 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YAR2;Q9H361;H0YAP2 A0A087WTT1 PABPC1;PABPC3 Polyadenylate-binding protein;Polyadenylate-binding protein 1;Polyadenylate-binding protein 3 0 187.16 0.006733499999999999 29218000.0 47728.0 43581.0 62674.0 39353.0 54266.0 57142.0 41325.0 50716.0 58927.0 46293.0 False True 47047.389967756775 43480.09087210864 57521.18564863625 42247.1508977596 51074.18057106091 54698.16986450795 43464.60629522208 53072.45050786059 52290.02073118072 54294.683368454855 0.8665192805064087 0.8008167314844407 1.0594257499999713 0.7781084311895102 0.9406847485316573 1.007431418161424 0.8005315363985521 0.97748890342909 0.9630781042838009 1.0 15.728523313242148 -1.522878747340394 0.07497400973545837 1.0852118417895258 0.5003832984197258 0.15344630135239934 0.08754807244284148 439.1796769605319 2.425696742882462 3.0751424983296176 26.824248663628495 0.029999999857696344 1.522878747340394 -0.5848285433698 NLDDGIDDERLR ddPTM_PC-9_AZD4547_30min_R2 4 NLDDGIDDERLR 12 1 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YAR2;Q9H361;H0YAP2 A0A087WTT1 PABPC1;PABPC3 Polyadenylate-binding protein;Polyadenylate-binding protein 1;Polyadenylate-binding protein 3 0 ;;; 215.77 1.0975000000000001e-10 72011500.0 292997.0 239442.0 324030.0 504929.0 433895.0 340698.0 272793.0 333616.0 282957.0 361482.0 False True 386163.9512838052 316836.9439564864 319733.1504825595 388525.42012528447 373656.1688228759 319394.100201446 297071.04852993495 282063.3129330178 297913.5293518354 348826.6252065571 1.1070369157031488 0.908293464608305 0.916596175229543 1.1138066651168608 1.0711801847167373 0.9156242015996264 0.8516295118069752 0.8086060310505097 0.8540446967757302 1.0 18.412150636648754 -6.943989239194735 5.050160280286012 0.8649070519426958 1.015563220886955 0.42301815126489484 0.08016211283202826 0.19678533632413917 10.490519770513325 0.03002251944735836 0.02610302611222794 1.1376554739258806e-07 6.943989239194735 0.15065616894425915 NLDDGIDDERLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NLDDGIDDERLR 12 1 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YAR2;Q9H361;H0YAP2 A0A087WTT1 PABPC1;PABPC3 Polyadenylate-binding protein;Polyadenylate-binding protein 1;Polyadenylate-binding protein 3 0 ;;; 196.02 1.7069000000000002e-05 57275700.0 249554.0 138811.0 205249.0 286690.0 318863.0 351625.0 256813.0 321290.0 295402.0 218693.0 False True 291798.5632838279 152591.23871006028 210142.91457116697 270627.68876152096 256384.08412719835 333185.16599956504 232485.81347489113 312856.4779348941 299721.69540432165 258340.30972716404 1.1295123226878512 0.5906598117468138 0.8134344763815649 1.047562763423694 0.9924277182990464 1.2897142004337048 0.8999207817023285 1.211024629742471 1.1601816833031628 1.0 17.978913244126595 -5.8338027765698826 3.7441503267249985 1.0969540704679788 0.817401566942622 0.3158160904646886 0.16204441773872585 0.23606868887575969 6.517289562863766 0.044864666515688996 0.07163864733338801 1.466213532149844e-06 5.8338027765698826 -0.27955250352535677 NLDDGIDDERLR ddPTM_PC-9_Lapatinib_30min_R1 4 NLDDGIDDERLR 12 1 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YAR2;Q9H361;H0YAP2 A0A087WTT1 PABPC1;PABPC3 Polyadenylate-binding protein;Polyadenylate-binding protein 1;Polyadenylate-binding protein 3 0 ;;; 212.68 3.4999000000000003e-09 67269200.0 519026.0 349446.0 407155.0 374336.0 433407.0 359417.0 311077.0 292083.0 381494.0 299530.0 False True 511624.5940622898 348636.87925689813 373680.28756374994 401865.9181882899 407914.85237094696 344045.57275194913 327183.0449485489 305654.2424814154 338526.128410085 351303.3614013634 1.456361225868715 0.9924097448603152 1.0636968746132234 1.1439284741974298 1.1611470233127232 0.9793403950919722 0.9313404905760151 0.8700578362306247 0.963629061389252 1.0 18.42235785530645 -6.846465132616402 3.9042977154961758 0.9332231759844353 1.1479863789670843 0.4562368037817909 0.11678903736301095 0.2197179008734151 6.413138118030807 0.0419751067611577 0.03731836497155832 1.424081574613604e-07 6.846465132616402 0.21476320298264906 NLDIERPTYTNLNR ddPTM_PC-9_AZD4547_30min_R2 3 NLDIERPTYTNLNR 14 1 Q9BQE3;F5H5D3;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;Q9NY65-2;Q9NY65;C9J2C0;C9JDS9;P68363;P68366-2;P68366;Q71U36-2;Q71U36 Q9BQE3;P68363;P68366-2;Q71U36-2 TUBA1C;TUBA1B;TUBA1A;TUBA3E;TUBA8;TUBA4A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-8 chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain;Tubulin alpha-1A chain 0 ;; 122.78 6.8397e-05 174687000.0 292368.0 236955.0 335856.0 416740.0 388711.0 310642.0 291889.0 321280.0 272236.0 310076.0 False True 385334.9423678179 313546.0698424219 331402.32999558776 320667.03156881686 334745.18729026424 291217.506632787 317866.5555360806 271633.558279939 286625.8391791907 299220.33361978916 1.2877966470602635 1.047876880723073 1.1075528390282838 1.0716752691556028 1.1187247311729005 0.9732544012293927 1.0623160254208683 0.9078044763665564 0.9579089619738145 1.0 18.19084869182703 -1.5228787452839172 0.28839495794047665 0.9601825645363935 3.0788842582140985 0.6323328872162075 0.061292028407346336 35.41793188014771 0.5021307626536352 0.06555335133771305 38.19409562950133 0.029999999999752728 1.5228787452839172 2.1187016936777052 NLDIERPTYTNLNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NLDIERPTYTNLNR 14 1 Q9BQE3;F5H5D3;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;Q9NY65-2;Q9NY65;C9J2C0;C9JDS9;P68363;P68366-2;P68366;Q71U36-2;Q71U36 Q9BQE3;P68363;P68366-2;Q71U36-2 TUBA1C;TUBA1B;TUBA1A;TUBA3E;TUBA8;TUBA4A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-8 chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain;Tubulin alpha-1A chain 0 ;; 101.38 0.0022345 213769000.0 336679.0 335255.0 304419.0 374150.0 385934.0 375594.0 373081.0 387381.0 361877.0 323040.0 False True 393672.10498663934 368536.9007768922 311677.50347548636 353187.5885106667 310313.0031504 355897.1894445517 337740.0668074673 377212.6592140964 367168.76652097615 381604.5948167663 1.0316230735525276 0.965755931093679 0.8167551117280006 0.925532850777794 0.8131794201781084 0.932633396658763 0.8850524113045305 0.988490873374366 0.9621707167789169 1.0 18.54171901705763 -7.768146969222154 24.98268275759297 0.9814981214146427 0.9063635871575666 0.22713853320823651 0.06181169615373415 249.45337334005362 929079.6174755029 0.03384006157740142 0.0168398345555574 1.7055051328088838e-08 7.768146969222154 -0.07513453425707606 NLDIERPTYTNLNR ddPTM_PC-9_Lapatinib_30min_R1 3 NLDIERPTYTNLNR 14 1 Q9BQE3;F5H5D3;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;Q9NY65-2;Q9NY65;C9J2C0;C9JDS9;P68363;P68366-2;P68366;Q71U36-2;Q71U36 Q9BQE3;P68363;P68366-2;Q71U36-2 TUBA1C;TUBA1B;TUBA1A;TUBA3E;TUBA8;TUBA4A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-8 chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain;Tubulin alpha-1A chain 0 ;; 109.95 0.0007011 290849000.0 447131.0 412071.0 497142.0 434987.0 427272.0 424057.0 379868.0 436940.0 511880.0 333631.0 False True 440754.829946216 411116.87491706695 456268.9037836163 466977.3950540931 402140.70100907236 405921.07063514803 399535.70633160125 457241.8275278937 454226.6840646363 391298.67381463735 1.1263897872421786 1.0506472483262688 1.1660374397275777 1.1934039809071921 1.0277078046003576 1.0373688892884863 1.0210504994475547 1.1685238364607757 1.1608183581010771 1.0 18.5779106951169 -6.272188968138902 24.972342899315315 1.0736675722848754 1.1304371493302265 0.19953387488162155 0.06311366612572271 1452.7330068379954 3374830.9118331885 0.021183510477286307 0.024224015834669328 5.343318129042238e-07 6.272188968138902 0.05676957704535113 NLDSATS(ph)PQNGDQQNGYGDLFPGHK ddPTM_PC-9_AZD4547_30min_R2 1 NLDSATSPQNGDQQNGYGDLFPGHK 25 0 Q92585 Q92585 MAML1 Mastermind-like protein 1 1 NLDS(0.097)AT(0.212)S(0.67)PQNGDQQNGY(0.021)GDLFPGHK 57.076 0.0029598000000000003 4816700.0 41549.0 46171.0 56765.0 61773.0 56666.0 59558.0 58781.0 65685.0 51236.0 59064.0 True False 54760.71772711263 61094.872826884726 56012.25901040791 47532.189233336205 48798.904026359094 55833.82884489404 64012.395126114316 55534.892541140915 53944.23035963288 56996.18733768245 0.9607786114301743 1.0719115730481936 0.9827369448162364 0.8339538389072347 0.8561783920254644 0.9796063816356374 1.1230995986953178 0.9743615342569517 0.9464533134476558 1.0 15.798577795441082 -6.99892948322838 24.999909113286417 1.0149150636897468 0.9420532594182571 0.161612372622566 0.0749579301900883 73.77701481669271 1722868.558179908 0.029689349522774994 0.025979859382262573 1.0024679964617951e-07 6.99892948322838 -0.0728618042714897 NLDSATSPQNGDQQNGY(ph)GDLFPGHK ddPTM_PC-9_AZD4547_30min_R2 1 NLDSATSPQNGDQQNGYGDLFPGHK 25 0 Q92585 Q92585 MAML1 Mastermind-like protein 1 1 NLDS(0.002)AT(0.014)S(0.041)PQNGDQQNGY(0.943)GDLFPGHK 52.019 0.029151999999999997 5311900.0 7945.6 10524.0 10899.0 14789.0 12526.0 13522.0 11050.0 15951.0 11978.0 9834.6 True False 10472.135521253125 13925.677191963256 10754.47213871991 11379.624537772306 10786.98111449854 12676.467202401982 12033.428593313554 13486.139467515255 12611.132626428343 9490.293647419265 1.1034574809074382 1.4673599900409955 1.1332075211017751 1.199080340455726 1.1366330184558502 1.335729712204337 1.2679722082768066 1.421045540691209 1.3288453545225907 1.0 13.212237012279527 -6.782123636163327 24.977034540195 1.296862256400125 1.2177145655818205 0.029439533674688323 0.1401275697449219 706.8530638220817 853546.3518462712 0.04749487614099411 0.04193014080441975 1.6514915800755695e-07 6.782123636163327 -0.07914769081830464 NLEELEEKS(ph)TTPPPAEPVSLPQEPPKPR ddPTM_PC-9_AZD4547_30min_R2 1 NLEELEEKSTTPPPAEPVSLPQEPPKPR 28 2 Q9UN86-2 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 NLEELEEKS(0.358)T(0.358)T(0.283)PPPAEPVSLPQEPPKPR 59.372 0.00060521 39866000.0 122590.0 46598.0 113380.0 304470.0 216800.0 104330.0 78255.0 77930.0 72113.0 150100.0 True False 161571.0699695959 61659.89222644466 111876.50711882395 234279.14551460784 186701.06224040277 97806.22860720319 85219.54339997745 65887.70915324814 75924.74595839268 144845.04468688404 1.1154753020296209 0.425695558724406 0.7723875356638594 1.617446741247215 1.2889710010031765 0.6752473225344636 0.5883497332214516 0.4548841093989761 0.5241791054883619 1.0 17.144150803657176 -6.906439909591664 7.371460882091433 0.601484178989925 1.0254579203532366 0.2695779990653506 0.32226444660900216 0.33617889125905404 22.830938969622995 0.12496135654813076 0.11018653005388909 1.2403952383979045e-07 6.906439909591664 0.42397374136331156 NLEELEEKS(ph)TTPPPAEPVSLPQEPPKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NLEELEEKSTTPPPAEPVSLPQEPPKPR 28 2 Q9UN86-2 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 NLEELEEKS(0.333)T(0.333)T(0.333)PPPAEPVS(0.001)LPQEPPKPR;NLEELEEKS(0.489)T(0.28)T(0.229)PPPAEPVS(0.002)LPQEPPKPR 60.17100000000001 0.00052126 55144000.0 135172.0 23762.5 66843.0 217409.0 182802.0 253065.0 174632.0 379543.0 237422.0 169063.0 True False 158053.9498313055 26121.483959108482 68436.79062348916 205228.2785794885 146983.2603551372 239793.82590452858 158089.59273380737 369580.3984090501 240893.8475917046 199712.78359802807 0.7914062734683455 0.1307952525046394 0.342676064048235 1.0276171353785832 0.7359732196762016 1.200693423747844 0.7915847442795761 1.8505595473193297 1.2062014421498612 1.0 17.607567156959334 -6.389740739538296 0.848783874561264 1.3091923434352746 0.3862557268096338 0.48636165948002874 0.32576985055488505 0.49236183750341855 0.7756145639384991 0.17726301586375703 0.2530951077021187 4.0762354391689954e-07 6.389740739538296 -0.9229366166256407 NLEELEEKS(ph)TTPPPAEPVSLPQEPPKPR ddPTM_PC-9_Lapatinib_30min_R1 2 NLEELEEKSTTPPPAEPVSLPQEPPKPR 28 2 Q9UN86-2 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 NLEELEEKS(0.333)T(0.333)T(0.333)PPPAEPVSLPQEPPKPR;NLEELEEKS(0.333)T(0.333)T(0.333)PPPAEPVSLPQEPPKPR 45.489 0.010020000000000001 12006600.0 86866.0 22337.7 41333.0 37664.0 30749.0 31211.0 15544.7 16512.5 35821.0 24544.0 True False 85627.27491072657 22285.97842807419 37934.76028999401 40433.9362034208 28940.404274859968 29876.17828639455 16349.528505198752 17279.731031844934 31786.461768147463 28786.397697175733 2.974574165600705 0.7741843443738948 1.3178015772955098 1.4046195230390992 1.0053499774200418 1.0378574839645787 0.5679602108325914 0.6002741716286463 1.104218113795672 1.0 14.813099642240926 -4.75783491239921 24.99995188619348 0.9803330256966407 2.974576982159687 0.8423727514364534 0.2589531515451397 42.68686665599752 296024.1628865498 0.0716137292957981 0.5146768449915479 1.7464859153873287e-05 4.75783491239921 1.994243956463046 NLEELEEKST(ph)TPPPAEPVSLPQEPPK ddPTM_PC-9_AZD4547_30min_R2 1 NLEELEEKSTTPPPAEPVSLPQEPPK 26 1 Q9UN86-2;Q9UN86 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 NLEELEEKS(0.119)T(0.439)T(0.439)PPPAEPVS(0.002)LPQEPPK 49.851000000000006 0.016769 4793500.0 15422.0 7712.6 17188.0 37199.0 34390.0 21483.0 12105.0 11812.0 10485.0 23250.0 True False 20325.875202472515 10205.547121886713 16960.0758895603 28623.345268820896 29615.54211460997 20139.664613903395 13182.321549507738 9986.726812757204 11039.21569444826 22436.024576749223 0.9059481608669886 0.45487323687739534 0.7559305273330941 1.2757761594932322 1.319999539726881 0.8976485359520607 0.587551573783208 0.44512015836827856 0.4920308255451083 1.0 14.453529448031883 -7.24139026073889 5.589770034119913 0.5835844853714334 0.9397057514533288 0.22637678679426454 0.27005127725573363 0.2667819771259738 28.79900777715405 0.11929290580759526 0.08811750408363152 5.736007879694378e-08 7.24139026073889 0.3561212660818954 NLEELEEKST(ph)TPPPAEPVSLPQEPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLEELEEKSTTPPPAEPVSLPQEPPK 26 1 Q9UN86-2;Q9UN86 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 NLEELEEKS(0.209)T(0.705)T(0.086)PPPAEPVSLPQEPPK 80.813 2.1167e-05 3676800.0 16611.0 5698.5 9235.6 28110.0 22562.0 31270.0 22713.0 47537.0 27925.0 16345.0 True False 19422.914217795194 6264.209419925499 9455.811730208045 26535.087833849626 18141.138062672173 29630.146152311092 20561.460212120142 46289.204119614864 28333.350296090335 19308.219113051193 1.0059402218336373 0.3244322732846589 0.4897298748705667 1.3742897611884621 0.9395552203159875 1.534587212773181 1.0649071305712412 2.397383406961968 1.4674243196742416 1.0 14.236927483493426 -6.30174520840277 0.9380757807932312 1.600606825004621 0.578097151760804 0.3866539254337906 0.43366870030832483 0.5318868531546684 1.0007867898520122 0.20951082393469306 0.3194477066199751 4.991772585516365e-07 6.30174520840277 -1.022509673243817 NLEELEEKST(ph)TPPPAEPVSLPQEPPKPR ddPTM_PC-9_AZD4547_30min_R2 1 NLEELEEKSTTPPPAEPVSLPQEPPKPR 28 2 Q9UN86-2 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 NLEELEEKS(0.053)T(0.473)T(0.473)PPPAEPVSLPQEPPKPR 75.297 1.3688e-05 42228000.0 140950.0 72712.0 145360.0 407880.0 297900.0 146840.0 115390.0 126440.0 106500.0 197550.0 True False 185769.16805787222 96214.73203934162 143432.43142346322 313849.56768318155 256541.72712830224 137658.07158709582 125659.48645995047 106901.60330215185 112129.37257594074 190633.83462953978 0.9744816203213815 0.5047096294648663 0.7523975568250861 1.6463476606505234 1.3457302982277086 0.7221072369163 0.6591667565421717 0.560769306822656 0.5881923992865308 1.0 17.540444673014157 -6.964019936047936 21.29682135838551 0.6690304950350124 1.0321163365549877 0.22642394928765397 0.3103625971518457 59.62350439513256 35290.2889127203 0.12238306123758232 0.10793011686803305 1.0863757529944857e-07 6.964019936047936 0.36308584151997525 NLEELEEKST(ph)TPPPAEPVSLPQEPPKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NLEELEEKSTTPPPAEPVSLPQEPPKPR 28 2 Q9UN86-2 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 NLEELEEKS(0.113)T(0.444)T(0.444)PPPAEPVSLPQEPPKPR;NLEELEEKS(0.13)T(0.435)T(0.435)PPPAEPVSLPQEPPKPR 69.99 7.4878e-05 51757000.0 142599.0 19699.2 66820.0 248760.0 210880.0 302160.0 190810.0 406290.0 253180.0 185767.0 True False 166738.19424136903 21654.806388522655 68413.24221626119 234822.78369080165 169559.57781474607 286314.19767772034 172735.09545523065 395625.31799983844 256882.27853049757 219445.08656923677 0.7598173959969786 0.09867984162721448 0.3117556345681781 1.070075376769546 0.7726742961786415 1.3047191083377745 0.7871449671338678 1.8028442750073392 1.1705993629046192 1.0 17.74350044269063 -6.124339656780917 1.0866695583540011 1.2499253281759597 0.3448775685384788 0.5049316398132788 0.3245169636881371 0.39586169085342526 0.963669575733894 0.1327363899043652 0.23373179014994533 7.510352881007822e-07 6.124339656780917 -0.9050477596374809 NLEELEEKST(ph)TPPPAEPVSLPQEPPKPR ddPTM_PC-9_Lapatinib_30min_R1 1 NLEELEEKSTTPPPAEPVSLPQEPPKPR 28 2 Q9UN86-2 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 NLEELEEKS(0.161)T(0.419)T(0.419)PPPAEPVSLPQEPPKPR 55.26 0.001532 19828000.0 169600.0 45087.0 82887.0 68499.0 50806.0 64109.0 35348.0 33040.0 71832.0 39374.0 True False 167181.47289916937 44982.60382163701 76072.35081307255 73536.64496596534 47817.69096843918 61367.20751537819 37178.14648090767 34575.159018450075 63741.52373550614 46179.74343744284 3.62023390462619 0.9740765208575155 1.6473099491365426 1.5924004659224968 1.0354689612603667 1.3288771861305158 0.8050747733423609 0.7487083393022125 1.3802918550609375 1.0 15.494972537448028 -4.758532217494378 24.9998019115447 1.1779518919388774 3.6202372010091066 0.8611322684703449 0.29539909073429943 29.57096094781192 254245.8145049987 0.0783779165197104 0.5330305005543539 1.7436840000469224e-05 4.758532217494378 2.442285309070229 NLEELEEKSTT(ph)PPPAEPVSLPQEPPKPR ddPTM_PC-9_Lapatinib_30min_R1 1 NLEELEEKSTTPPPAEPVSLPQEPPKPR 28 2 Q9UN86-2 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 NLEELEEKS(0.014)T(0.105)T(0.881)PPPAEPVSLPQEPPKPR 72.05199999999999 4.4518e-05 21175000.0 77594.0 24036.0 40579.0 37261.0 23291.0 24520.0 15740.0 17466.0 32198.0 19791.0 True False 76487.49533100311 23980.346118767433 37242.75125946982 40001.29823905222 21921.069171867828 23471.336758911733 16554.94018358851 18277.534122767815 28571.52218002879 23211.84798015015 3.295191981112929 1.0331080118771445 1.6044716168793773 1.7233138125520961 0.944391381100456 1.0111791520857576 0.7132107791566461 0.7874226187590939 1.230902520319021 1.0 14.502573765035274 -3.204489209160362 1.4812610796589059 1.0838652575873435 199.99999975682897 0.7882207213961481 0.33261131322715365 61.90187087975097 1.9316667770972924 0.10122096147009745 40429.5903358043 0.0006244688661573076 3.204489209160362 198.91613449924162 up NLEGNHDQHGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NLEGNHDQHGR 11 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 0 ; 82.48899999999999 0.0058418 1824540.0 4483.4 5458.4 4384.3 5533.700000000001 6858.6 6442.5 4731.9 6252.3 5792.4 5239.5 False True 5242.35106881362 6000.27387869112 4488.838339550342 5223.664729497458 5514.706564872061 6104.643958626934 4283.660176010712 6088.1837498594405 5877.102891855815 6189.379874140817 0.846991326338867 0.9694466975213817 0.725248478980047 0.843972229160128 0.8909950070947275 0.9863094660148574 0.6920984433202771 0.9836500382365972 0.9495463214998819 1.0 12.595579154954818 NLEPEWAAAASEVK ddPTM_PC-9_Lapatinib_30min_R1 2 NLEPEWAAAASEVK 14 0 Q15084-3;Q15084;Q15084-4;Q15084-5;Q15084-2 Q15084-3 PDIA6 Protein disulfide-isomerase A6 0 ; 159.0 0.0013117 10633100.0 55882.0 54656.0 55364.0 52777.0 47016.0 39152.0 55909.0 49604.0 44910.0 46155.0 False True 55085.112432496324 54529.44739005463 50812.18563122028 56658.396638910905 44250.611317012495 37477.56022776966 58803.694455162025 51908.78292830502 39851.76287673439 54132.830252328284 1.0175915830694457 1.007326739353505 0.9386574726348216 1.04665498505824 0.8174449979937868 0.6923258963751988 1.0862852391249733 0.9589150001273469 0.7361847272897826 1.0 15.724216198680056 -6.257050720515359 24.973179618387285 0.8805496856717516 0.998334040029642 0.21241148832873613 0.11372607067441406 655.3834804810241 3729387.420008872 0.035093256212671266 0.04375633025190903 5.532854881693166e-07 6.257050720515359 0.11778435435789036 NLEQILNGGES(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 NLEQILNGGESPK 13 0 Q13033-2;Q13033;G3V340;G3V3G7 Q13033-2 STRN3 Striatin-3 1 NLEQILNGGES(1)PK;NLEQILNGGES(1)PK;NLEQILNGGES(1)PK;NLEQILNGGES(1)PK 142.74 8.2855e-05 12248500.0 132465.0 126465.0 84495.0 88900.0 95035.0 104721.0 129136.0 105163.0 106863.0 97449.0 True False 174586.11455683582 167342.33809213512 83374.54109194771 68405.47849130839 81841.03067350846 98172.77931539231 140628.85383041966 88912.47475533224 112511.56001486166 94037.34017116722 1.8565615981806092 1.7795307458456162 0.8866110094159296 0.7274288954451116 0.8703035467032673 1.0439765643806784 1.495457587107912 0.9455018037887218 1.1964562142024389 1.0 16.520946112754174 -5.253411000058212 23.79845466279882 1.020709826602134 1.8180464641608864 0.7215751284530131 0.19811205452284367 171.17413546404438 507403.4199947256 0.055546470681021205 0.14107820060451054 5.579419294319554e-06 5.253411000058212 0.7973366375587525 NLEQILNGGES(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NLEQILNGGESPK 13 0 Q13033-2;Q13033;G3V340;G3V3G7 Q13033-2 STRN3 Striatin-3 1 NLEQILNGGES(1)PK;NLEQILNGGES(1)PK 132.81 5.157e-05 7353300.0 54182.0 66683.0 38724.0 49224.0 51755.0 32315.0 57974.0 34707.0 38896.0 42515.0 True False 63353.9424567202 73302.84754740579 39647.327021587815 46466.1388663612 41613.979276376136 30620.34451269371 52482.283024587414 33795.97802510621 39464.780415997455 50222.63295144516 1.2614619890193788 1.459558036677894 0.7894314712635344 0.9252031631094351 0.8285901560877583 0.6096921390460993 1.044992664469162 0.6729232626608783 0.7857967234444218 1.0 15.616050044288304 -5.265679690598182 24.98957489450821 0.8232603487015593 1.3605100339328757 0.7111661592418616 0.13461220758042808 156.6496584235619 923194.5402150787 0.03340021122858583 0.07372420532610854 5.424007850016101e-06 5.265679690598182 0.5372496852313164 NLEQILNGGES(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 5 NLEQILNGGESPK 13 0 Q13033-2;Q13033;G3V340;G3V3G7 Q13033-2 STRN3 Striatin-3 1 NLEQILNGGES(1)PK;NLEQILNGGES(1)PK;NLEQILNGGES(1)PK;NLEQILNGGES(1)PK;NLEQILNGGES(1)PK 152.94 9.012899999999999e-05 12558700.0 100051.0 98891.0 65123.0 81042.0 87446.0 79719.0 89059.0 88446.0 73680.0 77442.0 True False 98624.25439289371 98662.02396534516 59768.8383220497 87002.09902818671 82302.59820545083 76309.60420406553 93670.0392509662 92555.5240479972 65381.382515203506 90827.74651502144 1.0858383938500868 1.0862542312334926 0.6580460334570218 0.9578801893295676 0.9061393832097256 0.8401574092939227 1.0312932209044148 1.0190225740400816 0.719839311486061 1.0 16.47084546610479 -5.098756564087246 24.860616145497772 0.8965300707750847 1.0862656945601037 0.30265852648080005 0.11789845912150887 43.75190887530559 11004.890646842274 0.029282325460985054 0.07747383689634088 7.96605748232162e-06 5.098756564087246 0.18973562378501896 NLEQILNGGES(ph)PKQK ddPTM_PC-9_AZD4547_30min_R2 1 NLEQILNGGESPKQK 15 1 Q13033-2;Q13033;G3V340 Q13033-2 STRN3 Striatin-3 1 NLEQILNGGES(1)PKQK 96.37899999999999 0.0012530999999999998 55809000.0 68541.0 47299.0 52351.0 72565.0 73442.0 59621.0 55093.0 52460.0 46304.0 65581.0 True False 90335.61225863491 62587.476767642496 51656.79153446426 55836.26036807414 63245.84600119762 55892.88944493477 59996.17027071703 44353.51241087391 48751.53490851046 63285.02915130289 1.4274404779471466 0.9889776082429752 0.8162561071270482 0.8822980903521414 0.9993808464556192 0.8831929161524936 0.948031012631395 0.7008531560415782 0.7703486205553368 1.0 15.949576632383932 -4.772001257869597 3.002130986306777 0.8724532590514755 1.5256345728631553 0.769659841673205 0.09042735782366318 0.19000674060503425 2.434483794762959 0.02425288709840301 0.3059726812311034 1.6904360355387477e-05 4.772001257869597 0.6531813138116798 NLEQILNGGES(ph)PKQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NLEQILNGGESPKQK 15 1 Q13033-2;Q13033;G3V340 Q13033-2 STRN3 Striatin-3 1 NLEQILNGGES(1)PKQK;NLEQILNGGES(1)PKQK;NLEQILNGGES(1)PKQK 118.52 5.2696000000000005e-05 72400800.0 115963.0 75980.0 62554.0 126853.0 125512.0 127962.0 148663.0 147739.0 108509.0 96935.0 True False 135593.24552634946 83522.7922656734 64045.5245973661 119745.83767297477 100918.8245954309 121251.44745577317 134580.56441308567 143861.00779241006 110095.73884614045 114508.54816296244 1.184132081854539 0.7294022464314911 0.5593078038699778 1.0457371051684186 0.8813213180539904 1.058885553969426 1.175288365559904 1.2563342222073655 0.9614630576702281 1.0 16.805095775221837 -6.67781623159096 1.718451139147467 1.1209070852858385 0.843137222719542 0.25143786887762454 0.17661539836441953 0.446886112066191 2.7239639388534678 0.07345876328084217 0.07141213694669402 2.0998282220152624e-07 6.67781623159096 -0.27776986256629654 NLEQILNGGES(ph)PKQK ddPTM_PC-9_Lapatinib_30min_R1 1 NLEQILNGGESPKQK 15 1 Q13033-2;Q13033;G3V340 Q13033-2 STRN3 Striatin-3 1 NLEQILNGGES(1)PKQK 71.969 0.0097176 29704000.0 117530.0 56973.0 78860.0 87640.0 66858.0 67025.0 69852.0 63328.0 67564.0 56724.0 True False 115854.00064763743 56841.08251891067 72376.43520840316 94085.33795846972 62925.54388788541 64158.49699290619 73468.59477153914 66270.45007023009 59954.23083953862 66528.66782002097 1.741414708033168 0.8543847995375771 1.0878984591154308 1.4142074543412986 0.9458410328930223 0.9643736917515503 1.104314834174835 0.996118699528308 0.9011788872991102 1.0 16.021688524817797 -4.751937652240107 24.990096302115834 1.0411783670614414 1.7414160972266102 0.675345393797369 0.14782615939943577 237.564241981547 624763.6038789066 0.03797585302948057 0.47645551137953507 1.7703630952110725e-05 4.751937652240107 0.7002377301651688 NLES(ph)HLMSPAEIPGQPVPK ddPTM_PC-9_AZD4547_30min_R2 1 NLESHLMSPAEIPGQPVPK 19 0 Q9NRA8;Q9NRA8-3;Q9NRA8-2;B0QYZ7 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 NLES(0.989)HLMS(0.011)PAEIPGQPVPK 49.993 0.042976 5181800.0 11851.0 16067.0 19797.0 28499.0 24171.0 19791.0 17118.0 27340.0 20375.0 22396.0 True False 15619.371483886775 21260.343542690374 19534.47884486998 21928.9958551608 20815.27387183011 18553.4656413798 18641.46883803994 23115.23121069945 21451.980903613083 21611.92285681185 0.7227201201564402 0.9837321594912755 0.9038750959039685 1.0146712072058417 0.9631384495373283 0.8584828737500303 0.8625548481524561 1.069559213395664 0.9925993649774502 1.0 14.399539816974757 -4.757424705688582 24.986853621782068 0.9568162993302393 0.7227197788938161 0.5520394738037138 0.06428476776787535 97.11471203668295 604347.2556392365 0.016835400786173304 0.12533806329855143 1.7481363132653393e-05 4.757424705688582 -0.23409652043642315 NLES(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 1 NLESPEK 7 0 P26374 P26374 CHML Rab proteins geranylgeranyltransferase component A 2 1 NLES(1)PEK 75.652 0.032405 3912700.0 33715.0 35453.0 29188.0 33332.0 34172.0 36524.0 41978.0 46640.0 42222.0 37447.0 True False 44435.6686844353 46912.488928798295 28800.9480488996 25647.82237426645 29427.807651656065 34240.14850617734 45713.960677838586 39432.85968057872 44453.76872207863 36135.99192797972 1.2296789520264761 1.2982205946441572 0.7970155657080311 0.7097583601796084 0.8143628023358734 0.9475358687930622 1.2650534339543824 1.0912350146405216 1.2301798387235787 1.0 15.141148876169835 -7.240527175596135 23.879717818096694 1.1542199852211708 0.9549578676286489 0.18335703054746577 0.1854714204406789 823.5957774137994 940467.3695636785 0.07965605606269896 0.061617323215857604 5.747418537530972e-08 7.240527175596135 -0.19926211759252188 NLES(ph)PEKHLQN ddPTM_PC-9_AZD4547_30min_R2 1 NLESPEKHLQN 11 1 P26374 P26374 CHML Rab proteins geranylgeranyltransferase component A 2 1 NLES(1)PEKHLQN 125.36 0.0022447 4158200.0 23363.0 21653.0 23722.0 34584.0 26947.0 25176.0 19406.0 22484.0 19798.0 28835.0 True False 30791.948019411597 28651.90880250667 23407.430780320537 26611.193117473653 23205.87418907809 23601.740740102963 21133.096405596618 19009.614430920483 20844.481861581946 27825.49542669094 1.1066091563593565 1.0296998620561133 0.8412224264610045 0.9563600830606417 0.83397883247816 0.848205589089478 0.7594867973249166 0.6831725415636613 0.749114491653844 1.0 14.764119754206249 -4.559695570136648 0.5604720378544764 0.7845228659676999 1.4127874704284926 0.5407048072792355 0.0881064934395908 3.572567278551157 0.7140791906116989 0.047233081912549435 1.5433549265521567 2.756160027462173e-05 4.559695570136648 0.6282646044607927 NLFASFPTEES(ph)SINYTFKTPEK ddPTM_PC-9_AZD4547_30min_R2 1 NLFASFPTEESSINYTFKTPEK 22 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 NLFAS(0.004)FPT(0.098)EES(0.531)S(0.081)INY(0.089)T(0.098)FKT(0.098)PEK 55.126999999999995 0.0063521 23597000.0 47953.0 55197.0 49732.0 57669.0 62360.0 56717.0 58529.0 54292.0 57000.0 67893.0 True False 63201.056515637734 73038.35081383464 49072.52118568843 44374.30302716829 53702.39041195343 53170.477024007734 63737.96761430306 45902.418906045874 60012.90363219365 65516.08673502086 0.9646647054982658 1.1148155278143748 0.7490148394265631 0.6773039300506408 0.8196825098719982 0.8115636887632679 0.9728598087991827 0.700628215047363 0.9160025670476203 1.0 15.99956156716661 -5.262288992448717 24.998926240569226 0.8186858850849178 1.0397401230998475 0.37118862758162674 0.10780530653287676 68.33710455867497 2010821.9632568364 0.027182131575917555 0.06243779709339924 5.466520833050499e-06 5.262288992448717 0.22105423801492974 NLFASFPTEES(ph)SINYTFKTPEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLFASFPTEESSINYTFKTPEK 22 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 NLFASFPT(0.077)EES(0.28)S(0.28)INY(0.111)T(0.126)FKT(0.126)PEK 50.957 0.015683000000000002 16596000.0 40452.0 43459.0 33763.0 52207.0 49243.0 45691.0 47437.0 50505.0 42527.0 36858.0 True False 47299.72463658127 47773.32230947481 34568.03796689053 49282.01104737767 39594.18764383325 43294.88352559152 42943.4239458611 49179.29726447084 43148.87692182033 43540.06363223255 1.0863494604901187 1.09722674530288 0.7939363217030289 1.1318773317293542 0.9093736742847067 0.9943688620046129 0.9862967658611834 1.1295182680455154 0.9910154768326377 1.0 15.410055895523875 NLFASFPTEESSINYTFKT(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 1 NLFASFPTEESSINYTFKTPEK 22 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 NLFAS(0.005)FPT(0.164)EES(0.199)S(0.068)INY(0.044)T(0.122)FKT(0.398)PEK 45.912 0.045132 24370000.0 21941.0 17328.0 18134.0 20313.0 16958.0 20595.0 24430.0 23401.0 20907.0 20096.0 True False 28917.78159884901 22928.93713249136 17893.531311454888 15630.151682721546 14603.674416387204 19307.191394281086 26604.222672818996 19784.91315148418 22012.10133751356 19392.44515674636 1.4911880046642247 1.1823644180586843 0.922706299634937 0.8059917950720121 0.7530599828102024 0.9956037641578368 1.3718859307210036 1.0202381902625253 1.13508642977164 1.0 14.243207101153393 -4.874693069463144 2.874446317039525 0.9997044909305117 1.5284408651762262 0.4625079150226725 0.16230474462956318 0.3384805726283887 4.50955692603297 0.047312044081130836 0.3813662386834767 1.3344642097778718e-05 4.874693069463144 0.5287363742457145 NLFASFPTEESSINYTFKT(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLFASFPTEESSINYTFKTPEK 22 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 NLFASFPT(0.008)EES(0.008)S(0.008)INY(0.059)T(0.038)FKT(0.879)PEK 61.238 0.0046966 23760000.0 28764.0 33615.0 25084.0 36785.0 35181.0 29502.0 33738.0 36860.0 28740.0 25603.0 True False 33633.17708510392 36952.07504620436 25682.097691599745 34724.05570857908 28287.535598921622 27954.8631846972 30542.092398032382 35892.46405639827 29160.268129261825 30244.62122676353 1.1120382970887348 1.2217734442481756 0.849145952235421 1.1481068137117778 0.9352914485796212 0.9242920575893964 1.0098355065860642 1.1867387522326431 0.964147241607967 1.0 14.8843909725332 -5.233471771178088 24.995108308103553 1.0091763280224944 1.1669058871808884 0.30671034456911583 0.09860898433252101 908.1725430818966 811645.8822187668 0.024623407369675655 0.06511313121921046 5.841551755156353e-06 5.233471771178088 0.15772955915839404 NLFASFPTEESSINYTFKT(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 1 NLFASFPTEESSINYTFKTPEK 22 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 NLFAS(0.001)FPT(0.074)EES(0.074)S(0.023)INY(0.291)T(0.076)FKT(0.461)PEK 63.272 0.0030299 16680000.0 14066.0 12441.0 13617.0 14161.0 15938.0 13388.0 10257.0 12535.0 11637.0 8344.5 True False 13865.41626061151 12412.193628872763 12497.462823140064 15202.447179711182 15000.55817531362 12815.426448952308 10788.057272113556 13117.421861267294 10326.318516957428 9786.835706652657 1.4167414960472275 1.2682540098671018 1.2769666517079512 1.5533567370889074 1.5327281079334871 1.3094555618463024 1.1023028888469348 1.3403128707219079 1.0551233132418945 1.0 13.256626765712761 -7.9361402808767165 0.828417133207029 1.0112082321154758 1.3956782988724348 0.56788190839961 0.11799267092145727 0.4975876520586203 0.6563815437718465 0.11893938362795517 0.049245730110916465 1.1584031214829944e-08 7.9361402808767165 0.38447006675695894 NLFFSTNIDDAIK ddPTM_PC-9_Lapatinib_30min_R1 2 NLFFSTNIDDAIK 13 0 O60701;O60701-2;E7ER83;E7ETF4;E7EV97;E7ER95 O60701 UGDH UDP-glucose 6-dehydrogenase 0 ; 183.66 0.00025944 4075300.0 31903.0 31438.0 32277.0 32330.0 29999.7 25056.8 30593.5 26336.6 24284.9 32433.0 False True 31448.057369706312 31365.20724254498 29623.309652823067 34707.6560497184 28235.17662767949 23985.179074253676 32177.481734854817 27560.294582485232 21549.678830665922 38039.00083574398 0.8267319508601714 0.8245539197515446 0.7787615079780705 0.912422915617299 0.7422691450178113 0.6305417741602615 0.8459076481477587 0.7245273003224559 0.5665153751992457 1.0 15.215191731209316 -6.409895942980999 10.415497697036914 0.735916450251617 0.8306706201092164 0.10499356653274394 0.11454274558527332 0.897492166553637 77.46336796557483 0.03398993414486715 0.038533410841695204 3.891383714338766e-07 6.409895942980999 0.09475416985759944 NLFNQELLS(ph)PSKR ddPTM_PC-9_AZD4547_30min_R2 1 NLFNQELLSPSKR 13 1 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 NLFNQELLS(0.928)PS(0.072)KR 58.658 0.029577 13974000.0 25054.0 17250.0 19998.0 39200.0 28394.0 26410.0 24401.0 23985.0 29017.0 22644.0 True False 33020.65084442655 22825.72515786449 19732.813453538918 30163.045633962716 24451.98321611619 24758.578525028566 26572.64172899945 20278.66937046913 30550.779380620428 21851.240452297196 1.5111568112809415 1.0445963105707734 0.9030523231217489 1.3803813884072522 1.1190203718409764 1.1330513972000031 1.2160701717144804 0.9280328691059394 1.3981256326072171 1.0 14.415427560583367 -3.800172644286881 0.015553028625656001 3.5504638122572676e-07 2.4429965508560874 0.0644804489910209 0.19168805581291465 12430.015940321982 23.181940506983775 1566.8363436544548 2107.3437487530223 0.00015842632779970226 3.800172644286881 2.442996195809706 NLFNQELLS(ph)PSKR ddPTM_PC-9_Lapatinib_30min_R1 2 NLFNQELLSPSKR 13 1 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 NLFNQELLS(0.935)PS(0.065)KR;NLFNQELLS(0.998)PS(0.002)KR 81.44800000000001 0.017075 16747300.0 54246.0 47225.0 49985.0 44506.0 52976.0 45972.0 42147.0 56655.0 38832.0 44678.0 True False 53472.44209250194 47115.65341399535 45875.42624767981 47779.1197076637 49860.05583482334 44005.88472596616 44329.16543314515 59287.398129245994 34458.3312409118 52400.53277030713 1.020456076790162 0.8991445491694224 0.875476332440559 0.9118059909256846 0.9515181086684799 0.8397984218760117 0.8459678382938954 1.1314273919528033 0.6575950552250431 1.0 15.677293859655164 -4.760260657047538 23.80854183938439 0.9029435878735417 1.0204563187980804 0.08781542168192469 0.11500485084867786 41.02105820378848 827889.7848356861 0.026231753730113612 0.15665765048943575 1.7367581396377844e-05 4.760260657047538 0.11751273092453873 NLFNQELLSPS(ph)KR ddPTM_PC-9_AZD4547_30min_R2 1 NLFNQELLSPSKR 13 1 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 NLFNQELLS(0.099)PS(0.901)KR 82.837 0.0046146 13314000.0 35697.0 28467.0 41532.0 50451.0 40266.0 42135.0 33446.0 27838.0 38426.0 46667.0 True False 47047.90345627425 37668.401047474144 40981.25854347327 38820.30141017991 34675.76094175302 39500.29178917375 36422.629206512676 23536.276753601007 40457.119911766225 45033.20253432929 1.0447381222867536 0.8364584112968453 0.9100231881628409 0.8620373241407111 0.7700043299234451 0.8771370803367196 0.8087950036142181 0.5226427486621466 0.8983842506187592 1.0 15.458701458075437 -1.5228787452804073 0.5494128578484762 0.7919522467152235 10.905732873284908 0.1950498688632255 0.12123693070461389 198.97269956481387 1.825787918234726 0.059204732132219044 2374.197168363953 0.02999999999999518 1.5228787452804073 10.113780626569685 NLFNQELLSPS(ph)KR ddPTM_PC-9_Lapatinib_30min_R1 1 NLFNQELLSPSKR 13 1 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 NLFNQELLS(0.195)PS(0.805)KR 51.235 0.045749 9154200.0 25637.0 23026.0 20744.0 21070.0 21635.0 23263.0 15331.0 20826.0 24555.0 15401.0 True False 25271.411678750006 22972.684711713224 19038.508394155633 22619.558087459543 20362.47183604655 22268.095718701636 16124.764164840875 21793.65198905087 21789.357324386838 18063.042329457454 1.399067289873813 1.2718059501111316 1.0540034201828434 1.2522562741588255 1.1273002335182016 1.2327987341526916 0.8926937041244924 1.2065327419129992 1.2062949821499593 1.0 14.140753283662306 -1.52287876008648 0.7490862794263872 1.1191824232802936 52.39974759011987 0.39142294921422927 0.10947957056490096 391.27388890477357 1.6971226853571109 0.04021659237127921 33853.5904311551 0.029999998977227937 1.52287876008648 51.28056516683958 NLFPIFS(ph)PSALKPESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLFPIFSPSALKPESR 16 1 I3L4C2;I3L3J7 I3L4C2 BAIAP2 1 NLFPIFS(0.993)PS(0.007)ALKPESR 94.85600000000001 0.0011995999999999999 1513400.0 3773.0 3996.4 5965.2 4586.0 5449.9 4549.6 5258.2 6299.9 4309.7 4081.4 True False 4411.6943798531875 4393.136180712513 6107.432991146981 4329.061288012604 4382.031217434495 4311.01096688694 4760.105229928683 6134.534300295805 4372.721209348628 4821.325511655377 0.9150376528587582 0.9111884626110118 1.2667539199297966 0.8978985711599967 0.9088851617342774 0.8941547208263017 0.9873021886660222 1.272375052351432 0.9069541558182983 1.0 12.235214121199324 -7.550699416737207 24.999986759471 1.07976648748248 0.9686639927082183 0.0831486787913096 0.1350905490690505 479.1966563450288 430606.1413297381 0.06340362621963234 0.036606896435962676 2.8138476727417346e-08 7.550699416737207 -0.1111024947742616 NLGS(ph)INTELQDVQR ddPTM_PC-9_AZD4547_30min_R2 2 NLGSINTELQDVQR 14 0 A0A087X1A9;O75396 A0A087X1A9 SEC22B Vesicle-trafficking protein SEC22b 1 NLGS(0.912)INT(0.088)ELQDVQR;NLGS(1)INTELQDVQR 188.58 3.5042000000000003e-06 40758000.0 41607.0 42641.0 45151.0 41367.0 36441.0 24994.0 35882.0 43034.0 33113.0 36171.0 True False 54837.16052063769 56423.86935979711 44552.268238860685 31830.47726377899 31381.796167446984 23431.121228874064 39075.42848735536 36384.08412294221 34863.2855784707 34904.66429959554 1.57105537672434 1.6165137379777328 1.2763987029486181 0.9119261824313786 0.899071708528382 0.671289115625317 1.1194901676165998 1.0423845882214604 0.9988145217278219 1.0 15.091132215762823 -5.520530674684817 2.7325378622927445 0.9436090831088307 1.5943162852668522 0.8382564026145423 0.11390300722737635 0.10578369190899936 1.577662215962626 0.03477437513084035 0.07748213827778472 3.0162638236910713e-06 5.520530674684817 0.6507072021580215 NLGS(ph)INTELQDVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NLGSINTELQDVQR 14 0 A0A087X1A9;O75396 A0A087X1A9 SEC22B Vesicle-trafficking protein SEC22b 1 NLGS(1)INTELQDVQR;NLGS(0.988)INT(0.012)ELQDVQR 152.94 1.0524000000000001e-05 20408400.0 47666.0 56200.0 37463.7 29271.4 38024.0 18360.8 23726.8 26758.8 16002.2 16965.4 True False 55734.91235358657 61779.16458713921 38356.97668987346 27631.418357159215 30573.4701575679 17397.9273256589 21479.225736843757 26056.4098532922 16236.201901811877 20041.0927219675 2.7810316097432284 3.0826245576630487 1.9139164327017708 1.3787381127612761 1.525539080214704 0.868112710570349 1.0717592116771102 1.3001491592687047 0.8101455408174927 1.0 14.290673551834326 -5.526486480071129 1.441674160474161 1.090640623319268 3.061671107302956 0.912030555613405 0.22249383505992265 0.12110621642245041 0.4690351103317765 0.06891920316889982 0.2283601534493749 2.9751818771915715e-06 5.526486480071129 1.9710304839836879 up NLGS(ph)INTELQDVQR ddPTM_PC-9_Lapatinib_30min_R1 1 NLGSINTELQDVQR 14 0 A0A087X1A9;O75396 A0A087X1A9 SEC22B Vesicle-trafficking protein SEC22b 1 NLGS(0.998)INT(0.002)ELQDVQR 170.47 0.00026517 19642000.0 26813.0 29932.0 17014.0 7791.2 11972.0 10742.0 10539.0 10077.0 15070.0 8723.6 True False 26430.64170309802 29862.694293016608 15615.174595939274 8364.190838681285 11267.830497857614 10282.58970082504 11084.657852276961 10545.214207897141 13372.657905864784 10231.462636533664 2.5832710964238546 2.918712148386816 1.5261918213122232 0.8174970808978104 1.1012922490302972 1.004997043541831 1.0833893692478314 1.030665368433557 1.3070133157809518 1.0 13.320724779533899 -5.388426423208972 3.60540942593929 1.0566558413238039 2.754443524532434 0.95355219221784 0.14772758706436742 0.04071606878259614 0.9436954718398656 0.03837566547676723 0.08847885569889626 4.0885901383876045e-06 5.388426423208972 1.6977876832086303 up NLGSINT(ph)ELQDVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NLGSINTELQDVQR 14 0 A0A087X1A9;O75396 A0A087X1A9 SEC22B Vesicle-trafficking protein SEC22b 1 NLGS(0.041)INT(0.959)ELQDVQR;NLGS(0.093)INT(0.907)ELQDVQR 130.47 4.7377e-05 20510900.0 51670.0 66998.0 29851.0 31400.0 50185.0 31264.9 26740.9 22204.0 21922.0 23936.9 True False 60416.71047098179 73649.11866564317 30562.761050547917 29640.75980017352 40351.60950603685 29625.313605289146 24207.808364649496 21621.168527082675 22242.56777765056 28276.47048560385 2.1366425665374753 2.604607909008286 1.0808548777722475 1.0482482180816823 1.4270384108434153 1.0477019619677082 0.8561113869205919 0.7646346292791552 0.7866104713802496 1.0 14.787314431425918 -5.269857188067769 23.743065588104294 1.006333259643585 2.370625259070087 0.8759401945792407 0.20611002229513478 91.48718571535161 258047.94964469023 0.05860393565087207 0.1255417380058081 5.372084211331172e-06 5.269857188067769 1.3642919994265021 NLGSINT(ph)ELQDVQR ddPTM_PC-9_Lapatinib_30min_R1 1 NLGSINTELQDVQR 14 0 A0A087X1A9;O75396 A0A087X1A9 SEC22B Vesicle-trafficking protein SEC22b 1 NLGS(0.268)INT(0.732)ELQDVQR 109.99 0.0013139 20018000.0 32277.0 42125.0 21994.0 14067.0 15028.0 12056.0 12722.0 14228.0 22825.0 9370.0 True False 31816.72406112312 42027.46215065229 20185.73821929519 15101.53410613638 14144.082586184777 11540.392983908643 13380.682910775931 14889.084821867655 20254.208142094463 10989.59201525981 2.8951688121764114 3.824296852175608 1.8368050598480723 1.3741669467953728 1.28704346499349 1.0501202381202148 1.2175777674181103 1.35483508406801 1.8430354933986715 1.0 13.423850207284543 -5.4105473841160485 3.9274455154220025 1.3174070315761626 3.3485914950507816 0.8738269833180295 0.30709608423644974 0.06926672337065334 1.8456561104879459 0.08113443086319289 0.1804879378937521 3.885551019644835e-06 5.4105473841160485 2.0311844634746192 NLHYFNSDSFASHPNYPYS(ph)DEY ddPTM_PC-9_AZD4547_30min_R2 2 NLHYFNSDSFASHPNYPYSDEY 22 0 A0A0A0MSS8;P42330;S4R3Z2;P42330-2 A0A0A0MSS8;P42330-2 AKR1C3 Aldo-keto reductase family 1 member C3 1 NLHYFNSDSFASHPNY(0.075)PY(0.39)S(0.473)DEY(0.063);NLHYFNSDSFASHPNY(0.005)PY(0.026)S(0.942)DEY(0.026) 91.64299999999999 0.00011185 10541900.0 17286.1 15076.8 34388.0 52646.0 39105.0 37294.0 24743.0 40850.0 31717.0 36289.0 True False 22782.720226783837 19950.080757106745 33931.99265127994 40509.27807259187 33675.94575143422 34962.000284453454 26945.079066457653 34537.57113961494 33393.49586846117 35018.53315551194 0.650590363839892 0.5697006401870545 0.9689724152805933 1.1567954001013228 0.9616606612813994 0.9983856299517906 0.7694519626735559 0.9862655007917915 0.9535949355778488 1.0 15.095831033463993 -5.2658503344429155 24.496602009644683 0.9734978240122685 0.6101454803618548 0.7249295904450257 0.08974731221407635 134.8333740297532 748814.3868131466 0.0247425009009541 0.05454649266456608 5.421877056794742e-06 5.2658503344429155 -0.3633523436504137 NLHYFNSDSFASHPNYPYS(ph)DEY ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NLHYFNSDSFASHPNYPYSDEY 22 0 A0A0A0MSS8;P42330;S4R3Z2;P42330-2 A0A0A0MSS8;P42330-2 AKR1C3 Aldo-keto reductase family 1 member C3 1 NLHYFNSDSFAS(0.002)HPNY(0.099)PY(0.028)S(0.748)DEY(0.122);NLHYFNS(0.001)DS(0.001)FAS(0.017)HPNY(0.089)PY(0.281)S(0.33)DEY(0.281) 75.956 0.004350100000000001 1847400.0 7511.7 10894.7 14676.9 16839.4 17606.0 19985.0 16239.5 13218.3 13033.3 15228.300000000001 True False 8783.282447162255 11976.253815436046 15026.852958453212 15895.943012071399 14156.230685728495 18936.951418418197 14701.176996201524 12871.333630946527 13223.887355918856 17989.070242843525 0.4882566096297529 0.6657516844262966 0.8353323854761892 0.8836445017715787 0.7869350941780983 1.052692060388822 0.8172282834934173 0.7155085536489606 0.7351067719122187 1.0 14.134833003009218 -4.9573833348396805 1.991029343197016 0.8496507131024427 0.44718058688485496 0.5752754727407419 0.10076942814908782 0.39216503254843704 2.2453031384513116 0.028618554543354317 0.2564086719347897 1.1031045226288958e-05 4.9573833348396805 -0.4024701262175877 NLHYFNSDSFASHPNYPYSDEY ddPTM_PC-9_AZD4547_30min_R2 3 NLHYFNSDSFASHPNYPYSDEY 22 0 A0A0A0MSS8;P42330;S4R3Z2;P42330-2 A0A0A0MSS8;P42330-2 AKR1C3 Aldo-keto reductase family 1 member C3 0 ;; 167.9 7.0548e-09 28908700.0 36278.4 34755.9 92082.0 169075.0 119773.0 108812.0 64582.0 116680.0 76576.0 97330.0 False True 47814.176562402994 45990.064986331745 90860.93251469005 130097.37093271031 103144.58638247091 102007.96843867496 70329.67288808832 98649.78703966383 80623.65102699753 93922.5063249463 0.5090811396895539 0.48965968632926643 0.9674031930146324 1.3851565085221302 1.0981881810693885 1.086086524200655 0.7488053251556852 1.0503317138744406 0.858406085843383 1.0 16.519183286872263 -5.290778033540977 5.053441894234663 1.0369157992989102 0.4944558801586024 0.6427915666215694 0.1568222331192618 0.11124022595854956 7.955870914831994 0.04415556091434065 0.101492743520502 5.119434212593767e-06 5.290778033540977 -0.5424599191403078 NLHYFNSDSFASHPNYPYSDEY ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NLHYFNSDSFASHPNYPYSDEY 22 0 A0A0A0MSS8;P42330;S4R3Z2;P42330-2 A0A0A0MSS8;P42330-2 AKR1C3 Aldo-keto reductase family 1 member C3 0 ; 100.01 8.400600000000001e-05 15673200.0 23863.0 28299.0 39220.0 42726.0 61681.0 52067.0 50792.0 38212.0 35461.0 35918.0 False True 27902.53458426628 31108.337698424453 40155.15354267829 40332.20073956095 49595.05083076335 49336.51486128497 45980.61405776456 37208.97548896067 35979.550039379 42429.64907326846 0.6576187923704852 0.7331745224832259 0.9463937227794996 0.9505664463525118 1.1688772335854467 1.1627839479909339 1.0836906517507183 0.8769569464198816 0.8479813249751067 1.0 15.37278512599924 -5.259898566130305 1.7736601576590099 1.0247222515569532 0.643531063556791 0.6121351296682633 0.10067154414137121 0.32325289430454873 1.755076649426506 0.03319699864972239 0.14882387909701392 5.4966923967801014e-06 5.259898566130305 -0.38119118800016216 NLHYFNSDSFASHPNYPYSDEY ddPTM_PC-9_Lapatinib_30min_R1 1 NLHYFNSDSFASHPNYPYSDEY 22 0 A0A0A0MSS8;P42330;S4R3Z2;P42330-2 A0A0A0MSS8;P42330-2 AKR1C3 Aldo-keto reductase family 1 member C3 0 55.575 0.010872 11684000.0 17830.0 15053.0 24260.0 17795.0 25154.0 27676.0 24008.0 14584.0 28391.0 14764.0 False True 17575.74093037846 15018.145703353572 22265.436446308144 19103.703662379794 23674.491174666757 26492.361995907075 25251.016767953814 15261.625881509557 25193.306609516058 17315.937728206598 1.0150037038853899 0.8673019006582552 1.2858348647234459 1.1032439572279724 1.3672081492937265 1.5299409371721548 1.4582529207656747 0.8813629455740827 1.4549201437977979 1.0 14.079812896983602 -5.267839098420872 24.47563734382844 1.2707964650700072 0.9411527932154841 0.28317367115698744 0.20240791502275357 423.2826746382874 1618846.88150714 0.05312427001732148 0.11509127624983351 5.397105426096103e-06 5.267839098420872 -0.32964367185452315 NLIQHNNS(ph)TQTDIFYTDR ddPTM_PC-9_AZD4547_30min_R2 1 NLIQHNNSTQTDIFYTDR 18 0 Q8TDM6-4;Q8TDM6;Q8TDM6-3 Q8TDM6-4 DLG5 Disks large homolog 5 1 NLIQHNNS(0.757)T(0.215)QT(0.026)DIFYT(0.003)DR 79.143 0.0135 0.0 9636.6 9514.6 14652.0 14546.0 14102.0 18288.0 14241.0 18526.0 14204.0 15130.0 True False 12700.838346268107 12590.008381856092 14457.704906553272 11192.644433459735 12144.18071823873 17144.448468978502 15508.421411527434 15663.232385128676 14954.79444195927 14600.303305213583 0.8699023630374033 0.8623114272811278 0.990233189292075 0.7666035560687964 0.8317759202921624 1.1742528980789348 1.0621985781616998 1.0728018492284017 1.0242797104508852 1.0 13.833710719365865 -6.7492138606165994 24.999298284980746 1.0709749757395564 0.8656459419608431 0.6973177552977574 0.06668765334106429 128.0204370359344 261781.5876417019 0.022344154392659053 0.022186791376571858 1.7815012826982614e-07 6.7492138606165994 -0.20532903377871325 NLIQHNNS(ph)TQTDIFYTDR ddPTM_PC-9_Lapatinib_30min_R1 1 NLIQHNNSTQTDIFYTDR 18 0 Q8TDM6-4;Q8TDM6;Q8TDM6-3 Q8TDM6-4 DLG5 Disks large homolog 5 1 NLIQHNNS(0.471)T(0.471)QT(0.056)DIFYT(0.002)DR 79.34100000000001 0.01324 0.0 13491.0 8728.7 14762.0 12196.0 14217.0 14672.0 12280.0 7002.6 14838.0 12043.0 True False 13298.6158660536 8708.489231439731 13548.325342967883 13092.934524663335 13380.784011697424 14044.512762102488 12915.798313498537 7327.96636024814 13166.788188933075 14124.616503711179 0.9415204910207261 0.6165469504359015 0.9591995180476668 0.926958584767468 0.9473378628143061 0.9943287846726568 0.9144176275585939 0.5188081643365503 0.9321873047295522 1.0 13.785924077115867 -10.135502957179035 9.827598870492075 0.9999995063218357 0.8568092177645616 0.06919485803375569 0.1518746285759681 0.0 0.0 0.14994642108509268 0.03636734895983414 7.319763390414915e-11 10.135502957179035 -0.143190288557274 NLLDEELQR ddPTM_PC-9_AZD4547_30min_R2 2 NLLDEELQR 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 95.573 0.0248 4980000.0 22839.0 25614.0 31442.0 44143.0 35744.0 33355.0 28648.0 42412.0 30595.0 31251.0 False True 30101.32691928869 33893.22459092993 31025.05853616216 33966.51335255145 30781.562586351236 31269.306577142288 31197.61650147028 35858.19993080413 32212.189239069576 30156.912002064106 0.9981568045570578 1.123895728734099 1.0287876468929786 1.1263259762878437 1.0207133470510632 1.0368868859982097 1.0345096507008058 1.1890541023679677 1.0681527749547035 1.0 14.880201087088604 NLLDEELQR ddPTM_PC-9_Lapatinib_30min_R1 2 NLLDEELQR 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 111.06 0.010415 9340300.0 44415.0 47496.0 49844.0 48236.0 46739.0 45426.0 45020.0 39250.0 46075.0 42893.0 False True 43781.63395528656 47386.025930145515 45746.018723404086 51783.43635057896 43989.90391240953 43483.235873178004 47350.91531544819 41073.698289169624 40885.5483087405 50306.99789867007 0.8702891403592179 0.9419370646125999 0.909337082994838 1.0293485700514822 0.8744291201994475 0.8643575981370086 0.9412391375614161 0.816460929986352 0.8127208940412912 1.0 15.618471478019428 NLLEENFEEHS(ph)MSPER ddPTM_PC-9_AZD4547_30min_R2 2 NLLEENFEEHSMSPER 16 0 P38398-8;P38398-4;P38398;P38398-7;Q5YLB2 P38398-8 BRCA1 Breast cancer type 1 susceptibility protein 1 NLLEENFEEHS(0.5)MS(0.5)PER;NLLEENFEEHS(0.5)MS(0.5)PER 91.969 0.0021766 6258200.0 24196.0 27485.0 29289.0 29455.0 27829.0 35244.0 29860.0 42124.0 32126.0 28475.0 True False 31889.82469193525 36368.98875153077 28900.60872290738 22664.604825213566 23965.423713506298 33040.18710852353 32517.48215351515 35614.703713222494 33824.11477347113 27478.09891711545 1.1605542577063743 1.3235627712540694 1.0517688581762066 0.824824340780589 0.8721645476928831 1.20241895948426 1.1833963569168457 1.2961123628184825 1.2309481407537584 1.0 14.745994573744602 -6.89743647142822 23.846535807635785 1.2011998825626717 1.0486607751585963 0.16815509889379388 0.14834061926789566 14.992992003210325 3451.8437510914428 0.058431265161535205 0.05153153415480715 1.2663784997366816e-07 6.89743647142822 -0.1525391074040754 NLLEENFEEHS(ph)MSPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLLEENFEEHSMSPER 16 0 P38398-8;P38398-4;P38398;P38398-7;Q5YLB2 P38398-8 BRCA1 Breast cancer type 1 susceptibility protein 1 NLLEENFEEHS(0.5)MS(0.5)PER 64.565 0.020787 3912000.0 15784.0 16979.0 17801.0 13840.0 17589.0 14184.0 15837.0 12116.0 13936.0 14604.0 True False 18455.91945178975 18664.562909698176 18225.443350668444 13064.589669885403 14142.561713692972 13440.166070495066 14336.804710049162 11797.967837963142 14139.78763567824 17251.589594799618 1.0698097905918866 1.0819039490322961 1.05645008829577 0.7572977317883588 0.81978310670897 0.779068270586875 0.8310425327049805 0.6838771449513015 0.8196223054100817 1.0 14.074441680273683 -5.7539599386759965 24.46209257493945 0.7994101751582916 1.0706396866313295 0.7025331387462214 0.0761081626740603 62.41290708807178 204123.05999816975 0.01938400642894765 0.03272164218472739 1.7621385866969944e-06 5.7539599386759965 0.27122951147303787 NLLEENFEEHS(ph)MSPER ddPTM_PC-9_Lapatinib_30min_R1 1 NLLEENFEEHSMSPER 16 0 P38398-8;P38398-4;P38398;P38398-7;Q5YLB2 P38398-8 BRCA1 Breast cancer type 1 susceptibility protein 1 NLLEENFEEHS(0.822)MS(0.178)PER 122.33 4.1663000000000004e-05 3262800.0 18107.0 22082.0 18938.0 18026.0 20020.0 20013.0 18966.0 19808.0 21239.0 16032.0 True False 17848.790859582885 22030.870485714047 17380.990742794038 19351.69217297322 18842.4629608344 19157.090642581603 19947.96667864927 20728.351992659158 18846.84016341486 18803.10983870279 0.9492467476227995 1.1716610004780965 0.9243678780739994 1.0291750853436634 1.002092904975251 1.0188256520817747 1.0608865687520477 1.1023895605818144 1.0023256963920968 1.0 14.198683667933201 -7.245782873407218 20.44761730790004 1.0499329103802975 1.0187910942802691 0.0263106796199144 0.06718590084184575 266.7633914060363 348395.9443908517 0.024652790496144723 0.0189686676769649 5.678284216692224e-08 7.245782873407218 -0.031141816100028308 NLLEENFEEHSMS(ph)PER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLLEENFEEHSMSPER 16 0 P38398-8;P38398-4;P38398;P38398-7;Q5YLB2 P38398-8 BRCA1 Breast cancer type 1 susceptibility protein 1 NLLEENFEEHS(0.16)MS(0.84)PER 67.416 0.017345 4786400.0 13779.0 22193.0 21781.0 18838.0 25231.0 15466.0 22999.0 14828.0 15661.0 12890.0 True False 16111.512552344842 24396.174371572615 22300.341644902506 17782.567933620016 20287.166672248983 14654.935733663044 20820.368221659446 14438.780711564657 15890.012497298863 15226.854962816144 1.0580985102760239 1.6021807806765005 1.4645402283898914 1.167842471544183 1.3323280954465042 0.9624400947832155 1.3673452773079284 0.9482444501391812 1.0435518389123786 1.0 13.894330370087811 -6.815398532337568 0.6845594875229992 1.01293183755122 1.3877121254658837 0.32537383224467786 0.18040364287784844 0.8277092401894948 0.8448709246555501 0.1350598288037638 0.13226991985174766 1.529683096659443e-07 6.815398532337568 0.3747802879146638 NLLHADSNGYTNLPDVVQPS(ph)HSPTENSK ddPTM_PC-9_AZD4547_30min_R2 1 NLLHADSNGYTNLPDVVQPSHSPTENSK 28 0 Q8N4C8;Q8N4C8-4;Q8N4C8-3;Q8N4C8-2;Q8N4C8-5 Q8N4C8;Q8N4C8-3 MINK1 Misshapen-like kinase 1 1 NLLHADSNGYTNLPDVVQPS(0.916)HS(0.075)PT(0.008)ENS(0.001)K 213.71 1.1344e-45 5763700.0 8820.5 11345.0 17773.0 22659.0 19186.0 19110.0 15805.0 19258.0 18818.0 18758.0 True False 11625.235522202618 15012.04938643321 17537.318407328094 17435.317628060246 16522.35507446662 17915.04867903431 17211.614381657982 16282.118604815285 19812.68106229159 18101.28812949085 0.6422324996452952 0.8293359720613135 0.9688436691285008 0.9632086679872468 0.9127723373204688 0.9897112598217186 0.9508502521219249 0.8995005487089203 1.0945453671892287 1.0 14.143804746023878 -4.835017151165069 1.8432831312919375 0.9678326486672871 0.5579301349849018 0.8036334195385235 0.051011730432053884 0.3031326613241949 1.1812475926763373 0.013399650237177742 0.21028008107890236 1.4621194312710714e-05 4.835017151165069 -0.4099025136823853 NLLPAYRPNLS(ph)PPAEAGLALPPTGYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NLLPAYRPNLSPPAEAGLALPPTGYR 26 1 Q8N1G0;Q8N1G0-2;F8WCX2;H0Y5I5 Q8N1G0 ZNF687 Zinc finger protein 687 1 NLLPAY(0.019)RPNLS(0.981)PPAEAGLALPPTGYR;NLLPAY(0.047)RPNLS(0.948)PPAEAGLALPPT(0.003)GY(0.002)R 71.492 9.743e-05 12089100.0 20974.1 22886.0 22822.0 26646.0 28053.0 25050.0 27865.0 24120.0 22958.0 17666.6 True False 24524.600872642135 25157.970831695187 23366.163032916964 25153.111007497573 22556.216030145486 23736.333901995295 25225.42547487024 23486.875557252482 23293.71731773113 20869.414731271336 1.175145598879386 1.2054947949257895 1.1196367187961638 1.205261926670489 1.0808264783940777 1.1373742008408163 1.2087270198848332 1.1254209022957922 1.1161653365787565 1.0 14.349102521200425 -14.522878744396381 0.18953431196050297 0.3338661431233693 1.1813005054105432 0.5945133453579075 0.03963590123809224 96.9449176226083 0.9448329907384028 24.296395105670648 0.10881113099724952 3.000000006106153e-15 14.522878744396381 0.8474343622871738 NLLPAYRPNLS(ph)PPAEAGLALPPTGYR ddPTM_PC-9_Lapatinib_30min_R1 1 NLLPAYRPNLSPPAEAGLALPPTGYR 26 1 Q8N1G0;Q8N1G0-2;F8WCX2;H0Y5I5 Q8N1G0 ZNF687 Zinc finger protein 687 1 NLLPAY(0.181)RPNLS(0.819)PPAEAGLALPPTGYR 52.227 0.006351399999999999 6523900.0 11095.0 11240.0 11203.0 8574.7 8002.7 9209.2 6161.9 8442.3 6800.1 6852.6 True False 10936.783265426184 11213.97447058354 10281.932584830582 9205.31204236067 7531.996919913561 8815.343983693727 6480.933031591741 8834.560078131386 6034.201129772465 8037.062779484456 1.3607935592270852 1.3952826770506912 1.279314703261547 1.1453577376374746 0.9371579053904948 1.096836521694956 0.8063807897749763 1.0992274566627296 0.7507968141266073 1.0 12.972452635855205 -5.898769227891123 1.2670285605021172 0.9402526464025351 1.3956094109877653 0.7479236305779957 0.10440675495769317 0.21536617490244733 0.6988980829296694 0.03484578489091515 0.07414305896159434 1.2624982131128004e-06 5.898769227891123 0.4553567645852301 NLLQQS(ph)WEDMKR ddPTM_PC-9_AZD4547_30min_R2 1 NLLQQSWEDMKR 12 1 Q8TDM6-4;Q8TDM6;Q8TDM6-2;R4GMQ2 Q8TDM6-4 DLG5 Disks large homolog 5 1 NLLQQS(1)WEDMKR 91.789 0.0028485 3997700.0 17084.0 13425.0 18738.0 17181.0 14917.0 15916.0 16878.0 16229.0 16035.0 17888.0 True False 22516.356630724982 17764.36870981629 18489.52187680829 13220.185893803913 12846.03203616275 14920.770003951331 18380.109302981542 13721.18095531973 16882.577363898694 17261.746564683453 1.3044077866831947 1.0291176876713723 1.0711269457887183 0.7658660636839413 0.7441907450109942 0.8643835632761735 1.0647885041126832 0.7948894918543459 0.978034134647735 1.0 14.075290825104956 -4.736054594936517 1.2574466201794317 0.8872525943147288 1.5042523993100636 0.5509480965072167 0.10996525361596678 1.204058557172561 1.5323966621267169 0.033904974225083394 0.9951026095767096 1.836307487566075e-05 4.736054594936517 0.6169998049953348 NLLSVAYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NLLSVAYK 8 0 P31947-2;P31947;P63104;E7EX29;E7ESK7;E9PD24;E7EVZ2;E5RIR4;E5RGE1;I3L3T1;B4DJF2;K7EIT4;P62258;P62258-2;P27348;E9PG15;P31946-2;P31946;Q4VY20;Q4VY19;A0A0J9YWE8;A0A0J9YWZ2;P61981;Q04917;A2IDB2 P31947-2;P63104;I3L3T1;P62258;P27348;P31946-2;P61981;Q04917 SFN;YWHAZ;YWHAE;YWHAQ;YWHAB;YWHAG;YWHAH 14-3-3 protein sigma;14-3-3 protein zeta/delta;14-3-3 protein epsilon;14-3-3 protein theta;14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed;14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed;14-3-3 protein eta 0 ; 110.87 0.017301 31508000.0 218230.0 233090.0 209690.0 241200.0 297750.0 253440.0 237970.0 233380.0 205538.0 214367.0 False True 255172.02876102863 256229.63476185568 214689.80485375394 227686.34598095107 239408.02491625882 240149.16024437844 215427.75884639722 227254.02228655037 208543.6044103066 253230.04017176185 1.0076688713074862 1.011845334732243 0.8478054369384189 0.8991284992353794 0.945417158066524 0.9483438855891234 0.8507196014354222 0.8974212622341632 0.823534223146886 1.0 17.95008903337419 -5.24451970346417 24.640663941435495 0.8992193082941546 1.009757137129794 0.42354762240532107 0.050438098431055976 622.3060796609415 906280.0779675005 0.012598073900695906 0.033137324776868336 5.694823867507331e-06 5.24451970346417 0.11053782883563934 NLNIINTHAYNQPEDLVYS(ph)QPEMR ddPTM_PC-9_AZD4547_30min_R2 4 NLNIINTHAYNQPEDLVYSQPEMR 24 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 NLNIINTHAYNQPEDLVY(0.044)S(0.956)QPEMR;NLNIINTHAY(0.003)NQPEDLVY(0.2)S(0.796)QPEMR;NLNIINTHAYNQPEDLVY(0.005)S(0.995)QPEMR;NLNIINTHAYNQPEDLVY(0.094)S(0.906)QPEMR 109.74 5.1212e-07 55928300.0 80617.0 91353.8 144917.0 216070.0 173050.0 158758.0 131283.0 161147.0 123238.0 162437.0 True False 106251.52906223111 120882.12932907388 142995.30589291436 166258.39974822244 149024.99456043227 148830.8371630629 142966.9326711298 136245.43393967047 129752.10908463661 156750.13007197448 0.6778401332965014 0.7711772186317728 0.9122499983078524 1.0606587673763466 0.9507168797372284 0.9494782370816836 0.9120689890686796 0.8691886499686544 0.8277639643747583 1.0 17.258107114619563 -5.1344533669268175 2.7609519584387137 0.9363676914616167 0.6884742451247255 0.6686360497244773 0.06112952420171432 0.18364421316506313 2.5763174345244235 0.017803885754108566 0.06989818705465516 7.337474975141457e-06 5.1344533669268175 -0.24789344633689114 NLNIINTHAYNQPEDLVYS(ph)QPEMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NLNIINTHAYNQPEDLVYSQPEMR 24 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 NLNIINTHAY(0.024)NQPEDLVY(0.015)S(0.961)QPEMR;NLNIINTHAYNQPEDLVYS(1)QPEMR;NLNIINTHAYNQPEDLVY(0.001)S(0.999)QPEMR;NLNIINTHAYNQPEDLVY(0.453)S(0.547)QPEMR 126.04 1.2773e-07 46040700.0 55257.5 62548.4 79778.0 102875.0 128323.0 101941.0 110130.0 99780.0 95264.0 77220.0 True False 64611.503364626966 68757.79178402528 81680.21007974976 97111.24727525006 103179.02932436307 96595.03450312576 99697.68912784719 97160.88072564898 96657.05577821854 91219.37472681614 0.7083089920110235 0.7537630244664708 0.8954261123184161 1.0645901439916565 1.1311087105493074 1.0589311184428598 1.0929442284210116 1.0651342548293767 1.0596110318415048 1.0 16.477052660668015 -5.4943293891875875 2.069724577739386 1.0755168659236016 0.718002752102145 0.9448987877066682 0.03278123372977914 0.06596962494105084 0.5494917331061263 0.00946828460726844 0.025067342876529262 3.203838462287539e-06 5.4943293891875875 -0.3575141138214566 NLNIINTHAYNQPEDLVYS(ph)QPEMR ddPTM_PC-9_Lapatinib_30min_R1 4 NLNIINTHAYNQPEDLVYSQPEMR 24 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 NLNIINTHAY(0.001)NQPEDLVY(0.037)S(0.963)QPEMR;NLNIINTHAYNQPEDLVY(0.11)S(0.89)QPEMR;NLNIINTHAYNQPEDLVY(0.009)S(0.991)QPEMR;NLNIINTHAYNQPEDLVYS(1)QPEMR 110.9 3.6662e-07 37874300.0 148983.0 131174.0 117417.0 118678.0 115954.0 118154.0 112114.0 104819.0 130500.0 91075.0 True False 146858.4750998638 130870.27466230636 107763.42750272743 127405.97601820262 109133.81369433526 113100.8288504266 117918.7143419849 109689.27340057248 115801.71577407773 106817.19240019073 1.374858033617457 1.2251798771493705 1.0088584532253162 1.192747844755889 1.0216877193838356 1.0588260776101868 1.1039301042495322 1.0268878158641495 1.0841112106768962 1.0 16.7047843442555 -4.975557344405197 2.7900877941091644 1.0676313548819927 1.3814043758592913 0.7671127273515603 0.055155079151224445 0.1352579815826709 1.8924731507523473 0.013684977607804344 0.07994958831199829 1.0578952218945608e-05 4.975557344405197 0.31377302097729864 NLNNSNLFS(ph)PVNR ddPTM_PC-9_AZD4547_30min_R2 4 NLNNSNLFSPVNR 13 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;P52948-4;P52948-3;H0YEN4 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 NLNNS(0.002)NLFS(0.998)PVNR;NLNNS(0.014)NLFS(0.986)PVNR;NLNNS(0.032)NLFS(0.968)PVNR;NLNNSNLFS(1)PVNR 199.15 5.8049e-07 148565800.0 177385.0 200744.0 200888.0 225947.0 204479.0 200263.0 174945.0 243088.0 227730.0 183395.0 True False 233789.74016279244 265630.57223712164 198224.09386211247 173858.40999635152 176090.62041446142 187740.5229518288 190514.76608662808 205524.33520652913 239767.34287999079 176974.3968710931 1.3210370782225818 1.5009548100373244 1.1200721537505647 0.9823930075206797 0.9950061903176004 1.0608343707964587 1.0765103283578228 1.1613224220011418 1.3548137307942663 1.0 17.433181133169512 -5.317339424627424 6.871986989252671 1.089314747318414 1.4103182591831251 0.5690698233888187 0.11039923599328423 0.15864595864733874 16.43303786694405 0.030384974121209808 0.06444970125653217 4.815712765090014e-06 5.317339424627424 0.3210035118647112 NLNNSNLFS(ph)PVNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 NLNNSNLFSPVNR 13 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;P52948-4;P52948-3;H0YEN4 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 NLNNS(0.004)NLFS(0.996)PVNR;NLNNS(0.097)NLFS(0.903)PVNR;NLNNSNLFS(1)PVNR;NLNNSNLFS(1)PVNR;NLNNSNLFS(1)PVNR;NLNNSNLFS(1)PVNR 179.55 9.866299999999999e-05 127491400.0 173928.9 188465.6 198914.4 216212.0 261022.0 212544.0 287060.0 217046.1 200415.8 177246.5 True False 203371.62751763724 207175.2192422413 203657.27368306238 204098.34260876136 209876.61286210496 201397.81847767235 259867.59866557494 211348.86985435276 203346.50192555675 209379.8873674779 0.9713045033819524 0.9894704875766446 0.972668751729855 0.9747753004115098 1.0023723648955607 0.9618775757778664 1.2411297089365951 1.00940387594831 0.9711845033552239 1.0 17.675763340827864 NLNNSNLFS(ph)PVNR ddPTM_PC-9_Lapatinib_30min_R1 4 NLNNSNLFSPVNR 13 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;P52948-4;P52948-3;H0YEN4 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 NLNNS(0.004)NLFS(0.996)PVNR;NLNNS(0.003)NLFS(0.997)PVNR;NLNNS(0.182)NLFS(0.818)PVNR;NLNNSNLFS(1)PVNR 188.92 2.5676999999999998e-05 131399000.0 112860.0 125811.0 135223.5 123890.8 144772.2 166055.0 169570.0 154730.0 170061.0 141632.0 True False 111250.59570401063 125519.69235930484 124105.94580780489 133002.14271959363 136256.98382909637 158953.2147431115 178349.50488761798 161919.320669636 150906.93935827943 166112.902487223 0.6697288051574907 0.7556287951139707 0.7471180380906944 0.8006731610136294 0.8202673109006503 0.9568986656851521 1.0736643705406097 0.9747546292022105 0.9084600720277392 1.0 17.341804610539008 -6.559389819012217 1.616384625401168 0.9921776889647501 0.7350923877285912 0.8540751587168622 0.04739692254614653 0.14207524642685077 0.7588400936978086 0.02003694950647365 0.021379141729152933 2.758101096874507e-07 6.559389819012217 -0.2570853012361589 NLPMDTFTVAR ddPTM_PC-9_Lapatinib_30min_R1 1 NLPMDTFTVAR 11 0 Q6PKC3-2;Q6PKC3 Q6PKC3-2 TXNDC11 Thioredoxin domain-containing protein 11 0 90.149 0.0060355 10310000.0 48362.0 41263.0 40094.0 42182.0 51793.0 42130.0 36281.0 41007.0 42471.0 44581.0 False True 47672.34901149537 41167.458058691176 36797.62608731566 45284.20499502699 48746.63756895584 40328.19810982675 38159.452655703586 42912.334923413495 37687.468740542994 52286.76644955145 0.9117478905009689 0.7873399113026301 0.7037655717880281 0.8660739240534058 0.932293979509877 0.7712888145174774 0.729810910998321 0.8207112016540015 0.720784077877631 1.0 15.674158232456668 -4.754773158223366 24.560056831222557 0.8068796731073543 0.9117481128287618 0.08787732456322817 0.090748310360974 439.64197115531243 1619565.6782023301 0.02210486281758564 0.2066007847598499 1.7588420568446546e-05 4.754773158223366 0.10486843972140747 NLPTPT(ph)SAPTPGLAQGVHAPSTCSYMEATASSR ddPTM_PC-9_AZD4547_30min_R2 2 NLPTPTSAPTPGLAQGVHAPSTCSYMEATASSR 33 0 O43379;O43379-4 O43379 WDR62 WD repeat-containing protein 62 1 NLPT(0.348)PT(0.443)S(0.156)APT(0.053)PGLAQGVHAPSTCSYMEATASSR;NLPT(0.102)PT(0.65)S(0.188)APT(0.06)PGLAQGVHAPSTCSYMEATASSR 93.845 2.3708e-14 73189000.0 46270.0 45354.0 94967.0 189267.0 160667.0 163210.0 105515.0 185456.0 116861.0 140343.0 True False 60982.89752421239 60013.79355419056 93707.67552966456 145634.41729600058 138361.16036429335 153004.45289927727 114905.63059035985 156798.0365549187 123038.03388354002 135429.63428708437 0.4502921228816181 0.4431363480386652 0.6919288826478154 1.0753511819081196 1.0216461197184858 1.1297708489335334 0.8484526388573299 1.1577823227561665 0.9085015589920551 1.0 17.047183933889684 -5.553339949215587 2.8808143491085967 1.0248635411081894 0.45051125446190626 0.8703981877880113 0.08995139020600382 0.07820450842608616 1.3108983514171189 0.02399279046498198 0.05060524005466822 2.796791240696423e-06 5.553339949215587 -0.5743522866462831 down NLPTPT(ph)SAPTPGLAQGVHAPSTCSYMEATASSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NLPTPTSAPTPGLAQGVHAPSTCSYMEATASSR 33 0 O43379;O43379-4 O43379 WDR62 WD repeat-containing protein 62 1 NLPT(0.384)PT(0.488)S(0.116)APT(0.013)PGLAQGVHAPSTCSYMEATASSR;NLPT(0.286)PT(0.547)S(0.153)APT(0.014)PGLAQGVHAPSTCSYMEATASSR 88.056 1.4438999999999999e-11 44538000.0 37207.0 43647.0 58056.0 82515.0 130388.0 107449.0 110039.0 104339.0 115302.0 80127.0 True False 43505.41022825273 47979.985707026084 59440.27521860605 77891.95206723944 104839.40739808958 101814.18528684608 99615.30930663 101600.21180630865 116988.07362004662 94653.39081501686 0.45962864989460633 0.5069019217789502 0.6279782975210202 0.8229177147965607 1.1076138582608146 1.0756528045130862 1.0524219835009432 1.0733922042462072 1.2359628388662685 1.0 16.53036656877886 -5.871010638934155 1.5244258204011514 1.0992711151806789 0.4752993108425463 0.9448396286458567 0.06117143172344688 0.0809404202257796 0.382597379874689 0.020245296150229814 0.04026869933272232 1.345827384849784e-06 5.871010638934155 -0.6239718043381326 down NLPTPT(ph)SAPTPGLAQGVHAPSTCSYMEATASSR ddPTM_PC-9_Lapatinib_30min_R1 2 NLPTPTSAPTPGLAQGVHAPSTCSYMEATASSR 33 0 O43379;O43379-4 O43379 WDR62 WD repeat-containing protein 62 1 NLPT(0.062)PT(0.682)S(0.227)APT(0.028)PGLAQGVHAPSTCSYMEATASSR;NLPT(0.156)PT(0.65)S(0.156)APT(0.038)PGLAQGVHAPSTCSYMEATASSR 107.43 7.1737e-21 53482000.0 31959.0 16844.8 32019.0 19595.7 39713.0 37832.0 26114.6 27524.7 40410.0 22866.0 True False 31503.258799437204 16805.796900541434 29386.521416914286 21036.83314733891 37377.159418762036 36214.01355069939 27466.686208280833 28803.598045857536 35858.60026383515 26818.357632970183 1.1746900847018111 0.6266527253660223 1.0957614116081005 0.784419144350453 1.3937154515685548 1.3503441950590702 1.024174805339817 1.0740254284045612 1.3370915831083927 1.0 14.710933268271317 -6.253202419822011 24.995435538009925 1.1993299432150715 0.9119274461835788 0.33290242373806955 0.19135346577714582 706.1413805032405 2142817.729841042 0.055338735811585126 0.07019324011141137 5.582099586490858e-07 6.253202419822011 -0.2874024970314927 NLPVTIISQDFGDAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 NLPVTIISQDFGDASPR 17 0 Q9BXL7 Q9BXL7 CARD11 Caspase recruitment domain-containing protein 11 1 NLPVTIIS(0.001)QDFGDAS(0.999)PR 96.805 0.011359999999999999 0.0 6710.1 5813.0 6638.4 4726.1 5904.0 7935.1 5660.9 5585.4 6386.1 3780.7 True False 6614.4127435183655 5799.540355649656 6092.616376965039 5073.67315980743 5556.738327710602 7595.734270621559 5953.993703003572 5844.918074505178 5666.830169385738 4434.188957533912 1.4916849071756726 1.3079145726967596 1.3740091898008484 1.1442167233732794 1.2531577659245716 1.7129929155851649 1.3427469510263956 1.3181481733146185 1.2779857204230114 1.0 12.114454534860226 -8.788910686160547 1.4806301744827712 1.000752328835225 1.368260178701167 0.3788896356953688 0.1425106765701045 1.0993162788171869 4.134773529528346 0.14296261303022353 0.04166110461941948 1.62588308864305e-09 8.788910686160547 0.3675078498659421 NLQEAEEWYK ddPTM_PC-9_Lapatinib_30min_R1 3 NLQEAEEWYK 10 0 P08670;B0YJC4;B0YJC5;H7C5W5;P41219;P41219-2;F8W835 P08670 VIM;PRPH Vimentin;Peripherin 0 ;; 180.07 0.0032754 65442000.0 151192.0 142972.0 152561.0 140308.0 162797.0 122342.0 131011.0 143086.0 140392.0 149476.0 False True 149035.97435478278 142640.95711817377 140018.02348249042 150626.71837376698 153221.6005312165 117109.7178531313 137794.1085382536 149734.29792112412 124579.57456669986 175312.72743575 0.8501149718830463 0.8136372025268385 0.7986757466528226 0.8591887227866548 0.8739901704362586 0.6680046541176001 0.7859903302728176 0.854098274045733 0.7106134071889147 1.0 17.419571211788707 -11.24628386979025 2.7068019750321657 1.035144732424105 0.802838986147503 0.4683397191904296 0.06340661255428012 50854746.84549361 41107035.674474165 12065759.13267937 0.01571981074367695 5.671737599726411e-12 11.24628386979025 -0.23230574627660194 NLQEEIDALESR ddPTM_PC-9_Lapatinib_30min_R1 1 NLQEEIDALESR 12 0 Q9NQP4;E9PQY2 Q9NQP4 PFDN4 Prefoldin subunit 4 0 114.71 0.0034843000000000005 2229400.0 16160.0 16730.0 19870.0 16167.0 18723.0 15117.0 17489.0 18020.0 16036.0 16691.0 False True 15929.55543661895 16691.262712888136 18236.365300418092 17355.975111531006 17621.749950834284 14470.48114944816 18394.49484566579 18857.27498524426 14229.856813433813 19576.017110640478 0.8137281116269812 0.8526383389711922 0.9315666816875522 0.8865937853158713 0.9001703385953848 0.7391943451859152 0.9396443996602111 0.9632845577660664 0.7269025529048615 1.0 14.256799647083955 -11.036147535248709 2.8696884178163065 1.0053245621554445 0.8668900525312426 0.22309633767800674 0.07693892128712773 32623022.76017588 35518693.947085656 1363069.1599550217 0.019210032307044357 9.201369366668484e-12 11.036147535248709 -0.1384345096242019 NLQPLMRS(ph)PISR ddPTM_PC-9_AZD4547_30min_R2 1 NLQPLMRSPISR 12 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;H3BSK8;Q7Z6E9-4 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 NLQPLMRS(0.998)PIS(0.002)R 68.168 0.033402999999999995 0.0 17954.0 17576.0 44376.0 81156.0 65837.0 31790.0 26658.0 55371.0 21424.0 43306.0 True False 23662.998533600796 23257.098282587038 43787.54524523668 62446.73804770092 56696.668979342176 29802.166274542138 29030.510356611077 46814.684248999256 22556.428902037154 41789.87012132052 0.5662376663269004 0.5565247801696718 1.0478028555273489 1.49430323344895 1.3567084275386738 0.7131433093240831 0.6946781665588422 1.1202400034527782 0.5397582915800743 1.0 15.35086565446682 NLQPLMRS(ph)PISR ddPTM_PC-9_Lapatinib_30min_R1 1 NLQPLMRSPISR 12 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;H3BSK8;Q7Z6E9-4 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 NLQPLMRS(0.798)PIS(0.202)R 53.034 0.04363 6754400.0 40601.0 20005.0 32586.0 26835.0 23358.0 22238.0 12602.0 14360.0 30427.0 18272.0 True False 40022.02229468848 19958.679651603525 29906.90486559757 28808.535418935757 21984.128363594882 21286.93257930993 13254.46989794043 15027.218023757348 26999.99084948557 21430.290854090425 1.8675445222456901 0.9313303205959049 1.3955435821763102 1.3442904538758063 1.0258436767506003 0.9933104839427258 0.6184923008364366 0.7012139091378261 1.2598984789015149 1.0 14.387363810100837 -6.426153540280533 1.993364075013873 0.873200870502859 1.3629534968329242 0.4074128426801147 0.2673354321867746 0.33966964616782636 2.675679765372769 0.09445875586822898 0.10937149732144681 3.748404578860518e-07 6.426153540280533 0.4897526263300652 NLQS(ph)PTQFQTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLQSPTQFQTPR 12 0 O75385 O75385 ULK1 Serine/threonine-protein kinase ULK1 1 NLQS(0.712)PT(0.288)QFQTPR 143.56 8.5802e-05 5469700.0 18113.0 13800.0 14824.0 26053.0 29532.0 30095.0 29872.0 26007.0 23294.0 24316.0 True False 21179.17315194297 15169.972798977247 15177.460380333068 24593.334874965618 23745.416597235835 28516.76522078036 27042.30790544856 25324.34380669423 23634.630682081577 28724.298314649892 0.7373260408293847 0.5281233551052593 0.5283840257498057 0.8561857492763396 0.826666550288724 0.9927749986580634 0.9414436380385491 0.8816348977192725 0.8228096792194748 1.0 14.809984030285438 -5.842104584453315 5.140377338884237 0.9042578818313541 0.5915626551866208 0.7610487192835191 0.07859481118345073 0.09541639857307951 4.363577219307166 0.022743241013743157 0.034729608546766606 1.4384521362630123e-06 5.842104584453315 -0.31269522664473337 NLQSPT(ph)QFQTPR ddPTM_PC-9_AZD4547_30min_R2 2 NLQSPTQFQTPR 12 0 O75385 O75385 ULK1 Serine/threonine-protein kinase ULK1 1 NLQS(0.233)PT(0.766)QFQT(0.001)PR;NLQS(0.105)PT(0.895)QFQTPR 137.09 0.00015983 27664000.0 53776.0 47634.0 69515.0 102244.0 79215.0 83511.0 53632.0 75668.0 60015.0 73930.0 True False 70875.64938971348 63030.75896636048 68593.18567970586 78673.2254540531 68217.36460043133 78289.0439683325 58405.144101049074 63975.24927765936 63187.270376949215 71341.73320254065 0.9934668840816644 0.8835047333012622 0.9614734966554344 1.1027658275514305 0.9562055971749499 1.0973807399109339 0.8186673000393145 0.896743692727962 0.8856985601619637 1.0 16.122458645148626 -7.271635703459966 24.99063487824213 0.891672702308252 0.9949246152981162 0.2980559580031964 0.07368015214549728 906.5342517221685 2221856.5187258204 0.030801631013584994 0.021028855773668274 5.350129528140273e-08 7.271635703459966 0.10325191298986414 NLQYYDISAK ddPTM_PC-9_AZD4547_30min_R2 2 NLQYYDISAK 10 0 F5H018;B5MDF5;J3KQE5;P62826;B4DV51 F5H018 RAN GTP-binding nuclear protein Ran 0 ; 156.48 0.00054721 8141200.0 44243.0 35839.0 52994.0 62260.0 63543.0 50056.0 50244.0 56134.0 47175.0 46042.0 False True 58311.35368843158 47423.25588015685 52291.2649343355 47906.91890741121 54721.151282019804 46925.990406998455 54715.618664474765 47459.78013099497 49668.57419032869 44430.083594094096 1.3124295290811172 1.0673681443728056 1.1769337508355793 1.0782540799400897 1.2316238650807683 1.0561760548484795 1.2314993409498758 1.0681902056403874 1.1179041354973036 1.0 15.439249235294655 -14.522878745263608 0.10547575953924433 0.5301073873507652 1.23543402757535 0.29644292746195844 0.07907145242057134 230.44793619779972 1.6273149675532885 23.47830536111366 1.0546370488701582 3.000000000115566e-15 14.522878745263608 0.7053266402245847 NLQYYDISAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NLQYYDISAK 10 0 F5H018;B5MDF5;J3KQE5;P62826;B4DV51 F5H018 RAN GTP-binding nuclear protein Ran 0 ; 166.66 0.00060416 9513900.0 49302.0 53505.0 48676.0 59769.0 65587.0 52502.0 58488.0 53138.0 47157.0 41076.0 False True 57647.85484111365 58816.62279777375 49836.62044475798 56420.33670371247 52735.698170218944 49748.70269551126 52947.59322354967 51743.1838043649 47846.58191272094 48522.75364256294 1.1880581894788924 1.2121451975095925 1.0270773339013999 1.162760405547594 1.086824102331252 1.0252654468453941 1.0911910237737492 1.0663694848302483 0.9860648524850231 1.0 15.566373804569793 -1.5228787452898436 0.2102989472662187 0.995827383931498 2.052256604701095 0.6080700358289113 0.04733024082957343 35.44670733131743 0.4416180868266735 0.0788319935115601 12.529427187518527 0.029999999999343347 1.5228787452898436 1.0564292207695969 NLQYYDISAK ddPTM_PC-9_Lapatinib_30min_R1 2 NLQYYDISAK 10 0 F5H018;B5MDF5;J3KQE5;P62826;B4DV51 F5H018 RAN GTP-binding nuclear protein Ran 0 ; 166.66 0.0028874 37629000.0 136448.0 128871.0 154332.0 132513.0 131647.0 119811.0 135597.0 112799.0 110824.0 137330.0 False True 134502.22649850126 128572.60711731054 141643.41869874817 142258.44807040953 123903.7822879604 114686.96282308229 142617.54917878346 118040.05333299487 98341.83409154337 161067.30751927762 0.835068447905874 0.7982539045170425 0.8794051436030575 0.8832236054693041 0.769267110727177 0.7120437076242538 0.8854531150693882 0.7328616536218379 0.6105635936068103 1.0 17.29730416856725 -6.278635293953399 23.117927311060136 0.7730462869582055 0.8475365932662468 0.08154500815014043 0.10038312543320807 695.9058205782408 935561.8911722418 0.03033408550316762 0.034506330606293996 5.264591837056761e-07 6.278635293953399 0.07449030630804121 NLRGY(ph)Y(ph)NQSEAVDVWLR ddPTM_PC-9_AZD4547_30min_R2 1 NLRGYYNQSEAVDVWLR 17 1 A0A140T9Z4 A0A140T9Z4 2 NLRGY(0.984)Y(0.984)NQS(0.032)EAVDVWLR 60.345 0.020794 137140000.0 14091.0 6625.9 27701.0 56512.0 46340.0 28094.0 13884.0 26178.0 15169.0 21254.0 True False 18571.64488899238 8767.592598463443 27333.66664048814 43484.031501696445 39906.49088662481 26337.27773881684 15119.649103128075 22132.79161059582 15970.80237187273 20509.903929214102 0.9054964349461977 0.42748091988743897 1.3327057374244615 2.120147985664537 1.94571807963383 1.2841248710727642 0.7371877096699511 1.0791270250208287 0.7786873320807749 1.0 14.32403311363094 -7.156334117605384 6.141793253573291 0.9073186646131601 1.3625596855553672 0.18027665845959906 0.4564909839738866 0.4937013661423722 24.497288277460946 0.2048550012803525 0.1581332015777026 6.976954365771926e-08 7.156334117605384 0.4552410209422071 NLRSS(ph)LKS(ph)S(ph)LHT(ph)LT(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLRSSLKSSLHTLTK 15 2 Q13415 Q13415 ORC1 Origin recognition complex subunit 1 5 NLRS(0.166)S(0.87)LKS(0.982)S(0.982)LHT(0.999)LT(1)K 48.111999999999995 0.039789 3494400.0 4487.7 3510.8 5402.6 5854.8 6396.6 4592.7 4672.5 5738.1 4542.5 2772.6 True False 5247.378973884748 3859.329021931111 5531.4184734746 5526.7745375177055 5143.232148377309 4351.850727013722 4229.886974029471 5587.480955019503 4608.925468934299 3275.2504321104743 1.6021306103617525 1.178330970998231 1.688853597039393 1.6874357097501138 1.5703324844882665 1.3287077789070065 1.2914697858092816 1.7059706031147963 1.407197881343212 1.0 11.677389506839125 -6.754730803205055 24.910092640358023 1.3873424060678357 1.540881703966286 0.16912035749167076 0.2107172238086116 365.3480150316385 1356598.445621933 0.07123551536586799 0.06969556824096029 1.7590135980992323e-07 6.754730803205055 0.15353929789845044 NLS(ph)DSEKELYIQHAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLSDSEKELYIQHAK 15 1 Q00059-2;Q00059 Q00059-2 TFAM Transcription factor A, mitochondrial 1 NLS(0.804)DS(0.193)EKELY(0.002)IQHAK 51.535 0.043220999999999996 6414100.0 16358.0 15904.0 15106.0 24014.0 19082.0 17509.0 15976.0 19648.0 16714.0 14062.0 True False 19127.08631477297 17482.844014125676 15466.184329824031 22668.57343443843 15343.019081283157 16590.797217167084 14462.637623776309 19132.2608187768 16958.41063021857 16611.32928526925 1.1514482668003376 1.0524650805417044 0.9310624131410891 1.3646453601121904 0.92364788017833 0.9987639720007011 0.8706490236516846 1.1517597713112029 1.0208942546974316 1.0 14.019879905982298 NLS(ph)FEIK ddPTM_PC-9_AZD4547_30min_R2 6 NLSFEIK 7 0 Q05209-2;Q05209-3;Q05209 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 NLS(1)FEIK;NLS(1)FEIK;NLS(1)FEIK;NLS(1)FEIK;NLS(1)FEIK;NLS(1)FEIK 99.28299999999999 0.011890999999999999 306019800.0 414257.7 431027.1 434096.0 603130.0 550874.0 534024.0 508531.0 496632.0 489237.8 453303.9 True False 545983.031504559 570348.1808806602 428339.6034067122 464087.6967656105 474394.653877397 500631.3948598967 553789.273844917 419888.93586803565 515097.9113092362 437433.86843596987 1.2481498825335655 1.3038500720575683 0.9792099659274808 1.0609322465700712 1.0844945673127213 1.144473327248042 1.265995419661884 0.9598912342323526 1.177544649551146 1.0 18.738705400202328 -5.244456125394824 24.766446693334505 1.09047896363496 1.2760000132934606 0.41867393893017624 0.0902121557769913 715.7028900258681 1043695.2359989667 0.022767186739122154 0.05989204230999283 5.695657616093293e-06 5.244456125394824 0.18552104965850047 NLS(ph)FEIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 NLSFEIK 7 0 Q05209-2;Q05209-3;Q05209 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 NLS(1)FEIK;NLS(1)FEIK;NLS(1)FEIK;NLS(1)FEIK;NLS(1)FEIK;NLS(1)FEIK 104.79 0.010297 278795000.0 456760.0 442892.0 395266.0 516696.0 548688.0 447891.0 522024.0 477220.0 429630.0 366137.0 True False 534080.4465787826 486859.3907887411 404690.64049465186 487747.1982710349 441176.5251897646 424402.8074929569 472574.10759352887 464693.4806563855 435912.5259698949 432514.73976110277 1.2348260012451349 1.1256480901845225 0.9356690149292498 1.1277007542920723 1.0200265670331747 0.9812447264279908 1.0926196592850286 1.0743991775009945 1.0078558853524133 1.0 18.722389773932754 -4.959045628686496 4.127056779465426 1.035587635720582 1.2248656153621686 0.58770747253974 0.05383925755732024 0.14448877714934266 5.26310963622955 0.013234810688828433 0.060343582418998495 1.0988903796217044e-05 4.959045628686496 0.18927797964158666 NLS(ph)FEIK ddPTM_PC-9_Lapatinib_30min_R1 4 NLSFEIK 7 0 Q05209-2;Q05209-3;Q05209 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 NLS(1)FEIK;NLS(1)FEIK;NLS(1)FEIK;NLS(1)FEIK 94.363 0.013472 260937000.0 591296.0 518254.0 483824.0 460698.0 573577.0 519202.0 490759.0 497558.0 484968.0 522551.0 True False 582864.010609593 517054.01470443007 444045.858334648 494579.26776347484 539840.3285557701 496996.9407789757 516168.0997177706 520676.36110478215 430345.79690055974 612873.2440945605 0.9510351711807844 0.8436557145977376 0.7245313164073058 0.8069845967809389 0.8808352032944644 0.8109294141453723 0.8422102036455205 0.8495661478484232 0.7021774910998749 1.0 19.22522919757686 NLS(ph)FNELYPSGTLK ddPTM_PC-9_AZD4547_30min_R2 1 NLSFNELYPSGTLK 14 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 NLS(1)FNELYPSGTLK 187.75 4.1162e-06 13899000.0 35394.0 39733.0 51417.0 63505.0 56597.0 46928.0 33869.0 58262.0 37958.0 48094.0 True False 46648.555759065755 52575.91522883652 50735.176984729005 48864.90339246942 48739.48348533238 43993.58474148203 36883.275387053065 49258.94662757026 39964.38238720712 46410.243698674305 1.005134902155195 1.1328515223965165 1.0931891957761524 1.0528904719771002 1.0501880533483303 0.9479283286491058 0.7947227260111678 1.061380908650073 0.8611112375681986 1.0 15.502155652621997 -6.744574525083987 3.7288575970289015 0.9263129115859476 1.0739283166846882 0.454096314000928 0.07373154596820376 0.19628769248996925 5.861915892746377 0.02520127522896356 0.02379575286593542 1.8006341184887074e-07 6.744574525083987 0.1476154050987406 NLS(ph)FNELYPSGTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLSFNELYPSGTLK 14 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 NLS(0.993)FNELYPS(0.007)GTLK 178.0 8.005600000000001e-05 7244300.0 51708.0 51898.0 52897.0 68767.0 77122.0 58716.0 73140.0 65783.0 59380.0 44057.0 True False 60461.143120447596 57050.0904580668 54158.265092989655 64914.207935622144 62010.49772490934 55636.82959638947 66211.64971225586 64056.26595284987 60248.32016407677 52044.1853449799 1.1617271501066848 1.096185675304643 1.0406208634835261 1.2472903073673276 1.1914971348646688 1.0690306559242955 1.272219927612769 1.230805430582624 1.157637875676504 1.0 15.667449366463885 -5.756615191033329 24.99992549608183 1.177874879643889 1.099178690135964 0.1135496746512561 0.0824336594916848 223.228235766193 1156796.3728251874 0.022025810082679356 0.03663459177879465 1.7513978368154495e-06 5.756615191033329 -0.07869618950792501 NLS(ph)GSTLYPVSNIPR ddPTM_PC-9_AZD4547_30min_R2 1 NLSGSTLYPVSNIPR 15 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 NLS(0.974)GS(0.025)TLYPVSNIPR 94.45 0.0030302 6240100.0 6763.1 9615.2 8697.5 15611.0 14702.0 9562.0 8710.8 10879.0 9451.0 9823.1 True False 8913.625118781087 12723.125364515878 8582.165467154453 12012.125137545709 12660.881074992618 8964.086628410574 9486.044324944403 9197.900524550085 9950.560565401096 9479.196258918935 0.9403355385109043 1.342215628518583 0.9053684756320485 1.2672092453243122 1.33564921847462 0.9456589338970911 1.0007224310836507 0.9703249382452462 1.0497261891838832 1.0 13.21054902285422 -6.796519320121262 24.999996455461172 0.9918964810946022 1.1603962743998273 0.25858627382545885 0.13954856006021812 249.63902360652764 177905.5352152633 0.04765272092479051 0.04202731777796849 1.5976464542209492e-07 6.796519320121262 0.16849979330522513 NLS(ph)GSTLYPVSNIPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLSGSTLYPVSNIPR 15 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 NLS(0.997)GS(0.002)T(0.001)LYPVSNIPR 148.52 0.00012861 8440700.0 9779.9 12308.0 9496.5 13731.0 14001.0 12594.0 12646.0 13864.0 11912.0 11697.0 True False 11435.443908170211 13529.856899261738 9722.932575676805 12961.696586502634 11257.604557019466 11933.54846953009 11448.079330888535 13500.08469012224 12086.19046471005 13817.573506598941 0.8276014527955229 0.979177486756282 0.7036642555969299 0.9380588118682661 0.8147309331586406 0.8636500803727162 0.8285158986432174 0.9770228241358675 0.8746970268649539 1.0 13.75421666695759 -8.441706281255172 0.7550691687566692 0.9949355751742484 0.8518055645097201 0.23988816142897584 0.07702945531250244 0.9487776039430798 1.2298092783031918 0.07013275783101897 0.02706208603640055 3.6165437128521318e-09 8.441706281255172 -0.14313001066452824 NLS(ph)GSTLYPVSNIPR ddPTM_PC-9_Lapatinib_30min_R1 1 NLSGSTLYPVSNIPR 15 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 NLS(0.977)GS(0.002)T(0.021)LYPVSNIPR 145.04 0.00010926 7988600.0 12867.0 10875.0 11703.0 10119.0 12667.0 13499.0 13664.0 11097.0 10416.0 10459.0 True False 12683.514220481185 10849.819605658013 10740.824514886408 10863.185015994444 11921.951964280188 12921.679237705945 14371.455061534525 11612.607131590206 9242.840394657427 12266.824214258515 1.0339688577046964 0.8844848035766725 0.8755994483398287 0.8855743610777 0.9718857754904925 1.0533842347464513 1.171570963316623 0.946667770627391 0.753482746081409 1.0 13.582474174322797 -4.237417185549779 6.947954961603254 0.9543351791321479 8.701671168499223 0.051097767361892976 0.10752105780817466 20135.224075362665 5828.624683248283 0.029300863537377923 2440605.9923576564 5.788723614438058e-05 4.237417185549779 7.747335989367075 NLS(ph)NEELTK ddPTM_PC-9_AZD4547_30min_R2 2 NLSNEELTK 9 0 Q0JRZ9-3;Q0JRZ9 Q0JRZ9-3 FCHO2 F-BAR domain only protein 2 1 NLS(1)NEELTK;NLS(0.991)NEELT(0.009)K 95.094 0.005536600000000001 122167000.0 376120.0 408120.0 370070.0 419600.0 415180.0 428780.0 524100.0 471570.0 446110.0 500710.0 True False 495718.3362179982 540036.8087784147 365162.6300005576 322867.7027553767 357539.4235284611 401968.3188171803 570743.8846837664 398699.69210056734 469690.46384838445 483180.2953042629 1.0259489905436643 1.1176714241592753 0.7557481825094118 0.6682137204127169 0.7399710356634377 0.8319220024567792 1.1812234278394236 0.8251571845443378 0.9720811639320188 1.0 18.882202095394348 -8.453766582811891 6.797328740257239 0.9998553364389887 0.8912162627047328 0.05300595596430557 0.1588670350105525 0.7815662190909434 60.684341082719016 0.16714870488003908 0.04326178177818254 3.517494420215738e-09 8.453766582811891 -0.10863907373425596 NLS(ph)NEELTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NLSNEELTK 9 0 Q0JRZ9-3;Q0JRZ9 Q0JRZ9-3 FCHO2 F-BAR domain only protein 2 1 NLS(0.964)NEELT(0.036)K;NLS(0.667)NEELT(0.333)K;NLS(1)NEELTK 107.39 0.0025059 130799000.0 332534.0 374113.0 334908.0 423581.0 509070.0 431820.0 484570.0 478531.0 397792.0 342789.0 True False 388825.43835412123 411252.4662133175 342893.4768656622 399849.12983812974 409321.3878895724 409174.59902433545 438668.02161700575 465970.06829550583 403608.95545147255 404933.93218376895 0.9602194517441989 1.015603864056226 0.8467886971498568 0.9874428840324213 1.0108349914815544 1.0104724907040934 1.0833076379924798 1.1507310977437109 0.9967279187368889 1.0 18.627327015801654 -6.622106721342726 1.525278691272886 1.066340148537964 0.9490858404299312 0.37614258690064406 0.05856015446814678 0.38160068557295956 1.8348792942096253 0.024671104680194848 0.02509993662816088 2.387224586261261e-07 6.622106721342726 -0.11725430810803283 NLS(ph)NEELTK ddPTM_PC-9_Lapatinib_30min_R1 1 NLSNEELTK 9 0 Q0JRZ9-3;Q0JRZ9 Q0JRZ9-3 FCHO2 F-BAR domain only protein 2 1 NLS(0.992)NEELT(0.008)K 87.21600000000001 0.011062 25032000.0 118290.0 124320.0 96531.0 110360.0 98729.0 126420.0 111400.0 109880.0 113170.0 110420.0 True False 116603.16290827094 124032.14467819805 88594.59380043583 118476.2425501676 92921.95432868217 121013.31129941352 117167.74691561377 114985.42593666121 100423.60286706807 129505.94987459818 0.900369156947452 0.9577331759529158 0.6840967066472452 0.914832427891454 0.7175110828395094 0.9344227922855424 0.9047286787137455 0.8878775534869453 0.7754362094120708 1.0 16.98265885541729 NLS(ph)PGAVESDVR ddPTM_PC-9_AZD4547_30min_R2 3 NLSPGAVESDVR 12 0 A0A3B3IU78;A0A3B3ISK1;A0A3B3ITV3;A0A3B3ISC6;A0A3B3IT15;A0A3B3IS84;P53621;P53621-2 A0A3B3IU78 COPA Coatomer subunit alpha;Xenin;Proxenin 1 NLS(1)PGAVESDVR;NLS(1)PGAVESDVR;NLS(1)PGAVESDVR 183.75 0.00021429 102344000.0 112397.0 117798.0 140378.0 203221.0 153000.0 130671.0 130707.0 152435.0 115985.0 135483.0 True False 148136.90799716683 155873.89983455787 138516.49599864404 156371.53818315148 131758.59097223976 122500.12171313899 142339.66978698914 128879.67335782653 122115.73031192938 130739.78140781548 1.1330668171693254 1.192245375937579 1.05948238942339 1.196051702850742 1.0077926515820486 0.9369766447063683 1.0887250097427517 0.985772440262947 0.9340365189307975 1.0 16.99633866459253 -6.333667077199477 6.720709391462877 0.9927004027774691 1.1422078361272665 0.6647885278085535 0.053242462695364846 0.1542044914361577 12.051975908708565 0.016302818224287273 0.01853652412329504 4.6380232650932883e-07 6.333667077199477 0.14950743334979744 NLS(ph)PGAVESDVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NLSPGAVESDVR 12 0 A0A3B3IU78;A0A3B3ISK1;A0A3B3ITV3;A0A3B3ISC6;A0A3B3IT15;A0A3B3IS84;P53621;P53621-2 A0A3B3IU78 COPA Coatomer subunit alpha;Xenin;Proxenin 1 NLS(1)PGAVESDVR;NLS(0.999)PGAVES(0.001)DVR;NLS(1)PGAVESDVR;NLS(1)PGAVESDVR 223.14 2.9665e-15 89924200.0 115991.9 136285.0 141244.0 165364.0 168656.0 145377.0 144077.0 139747.0 136838.0 108145.0 True False 135627.03772554803 149814.47412381257 144611.7926308531 156099.19119732114 135609.06750722643 137753.1741984178 130428.9835328505 136078.78932418613 138838.99687793737 127750.83242465123 1.0616528687242979 1.1727083986883193 1.131983172917066 1.2219035151053912 1.0615122025698742 1.0782957072288828 1.0209638642454941 1.065189061718614 1.0867952422918736 1.0 16.962973166233787 -6.399370020549996 8.80966117446672 1.0544225496825692 1.1477303104517105 0.5247455740831891 0.044274345840964915 0.2587727012340034 17.4433029710626 0.013317857985679553 0.015096010882893644 3.986850764150852e-07 6.399370020549996 0.09330776076914127 NLS(ph)PGAVESDVR ddPTM_PC-9_Lapatinib_30min_R1 2 NLSPGAVESDVR 12 0 A0A3B3IU78;A0A3B3ISK1;A0A3B3ITV3;A0A3B3ISC6;A0A3B3IT15;A0A3B3IS84;P53621;P53621-2 A0A3B3IU78 COPA Coatomer subunit alpha;Xenin;Proxenin 1 NLS(1)PGAVESDVR;NLS(0.999)PGAVES(0.001)DVR 190.34 0.00016561 34792000.0 60132.0 62443.0 55296.0 49942.0 58700.0 58066.0 48539.0 48443.0 61162.0 41789.0 True False 59274.506653141776 62298.41706998649 50749.77632873267 53614.901281628096 55247.38140864032 55582.65253845717 51052.11191684894 50693.8386298661 54273.29149558732 49012.172969657615 1.2093833646150998 1.271080494810016 1.0354524856539367 1.093909901012141 1.1272175474211843 1.1340581159881893 1.0416210672490323 1.0343111834941408 1.1073430988090807 1.0 15.580852490040312 -1.5228787452803405 0.33554248157806166 1.0468943744393482 3.19175098722168 0.5278463637898676 0.05532128548122985 47.69800139080852 0.677436918603537 0.05018462572819964 63.80449384878792 0.029999999999999798 1.5228787452803405 2.1448566127823314 NLS(ph)PSFSR ddPTM_PC-9_AZD4547_30min_R2 1 NLSPSFSR 8 0 Q1ED39;H3BNU8 Q1ED39 KNOP1 Lysine-rich nucleolar protein 1 1 NLS(0.732)PS(0.216)FS(0.051)R 82.831 0.015913999999999998 7278900.0 54304.0 71680.0 86582.0 89934.0 81622.0 91384.0 68008.0 108100.0 87119.0 73459.0 True False 71571.54240663118 94849.15822120165 85433.86610832618 69201.10576644905 70290.1941982756 85669.7440337453 74060.58025104691 91395.62889087832 91723.9324830364 70887.22276917931 1.009653638705527 1.3380289778038903 1.2052082557460768 0.9762140913854033 0.9915777689182754 1.2085357655031903 1.044766283088852 1.289310334366996 1.2939416851144658 1.0 16.113237988555156 -7.761994140719485 24.99999403549446 1.218719495437573 1.1169815110091137 0.06740169362079529 0.13258344258294427 36.037673923471864 1623731.0668264856 0.06857469007581982 0.03607588149782162 1.7298396971760538e-08 7.761994140719485 -0.10173798442845938 NLS(ph)PTAVINITSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NLSPTAVINITSEK 14 0 Q92870;Q92870-4;H0YAJ5;G5E9Y1;Q92870-2;D6RB55 Q92870 APBB2 Amyloid beta A4 precursor protein-binding family B member 2 1 NLS(0.624)PT(0.374)AVINIT(0.001)SEK;NLS(0.727)PT(0.272)AVINITSEK 133.32 0.00018414 0.0 15792.099999999999 25549.0 18569.7 20857.6 23232.0 18861.6 27370.0 20217.8 19763.6 17947.2 True False 18465.390621807455 28085.33587254128 19012.47207397943 19689.01629325156 18679.85637230742 17872.46449205088 24777.3154583599 19687.104172529802 20052.605260942204 21200.885290042967 0.8709726206801259 1.3247246748574035 0.8967772719806503 0.9286884025781009 0.8810885072370278 0.8430055748872296 1.1686924918176227 0.9285982119706995 0.9458381094283806 1.0 14.37183688853076 NLS(ph)PTAVINITSEK ddPTM_PC-9_Lapatinib_30min_R1 2 NLSPTAVINITSEK 14 0 Q92870;Q92870-4;H0YAJ5;G5E9Y1;Q92870-2;D6RB55 Q92870 APBB2 Amyloid beta A4 precursor protein-binding family B member 2 1 NLS(0.888)PT(0.112)AVINITSEK;NLS(0.956)PT(0.044)AVINITSEK 167.14 3.4009e-05 15607600.0 42827.0 85965.0 81368.0 73883.0 126609.0 105071.0 142431.0 143560.0 100480.0 112430.0 True False 42216.2791264901 85765.95332417372 74678.23712956307 79316.60228646279 119162.10754287113 100577.35826246404 149805.38025976467 150230.32169154636 89162.8842986923 131863.3756964415 0.320151663822674 0.6504152716491408 0.5663303910972025 0.6015059289021617 0.9036785757494215 0.7627391436876301 1.1360651088185918 1.1392876975740922 0.6761762606771977 1.0 17.00868439430962 -6.201203897915564 0.9638451875343967 0.9882920112786165 0.46995598718293197 0.6315325284181439 0.15310997172797955 0.3736510308608606 0.7301736520083328 0.0705925506284357 0.11986839928915602 6.292107039189671e-07 6.201203897915564 -0.5183360240956846 NLS(ph)SDEATNPISR ddPTM_PC-9_AZD4547_30min_R2 4 NLSSDEATNPISR 13 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 NLS(0.5)S(0.5)DEATNPISR;NLS(0.977)S(0.023)DEATNPISR;NLS(0.5)S(0.5)DEATNPISR;NLS(0.975)S(0.025)DEATNPISR 238.64 3.7703e-26 101397000.0 151290.0 156857.0 200936.0 255961.0 231653.0 210527.0 176622.0 234369.0 174050.0 200886.0 True False 199397.07297251088 207557.95774418264 198271.45735074978 196953.1460080291 199491.9795718452 197362.7134092654 192341.01583784827 198152.65631384114 183249.92766988275 193853.0422849396 1.0285991420213165 1.0706974484264142 1.0227926011050972 1.0159920302851515 1.0290887221600427 1.0181048029113053 0.9922001407392469 1.0221797603907687 0.9453033365374188 1.0 17.56460385102683 -6.806931456110348 0.5571200943941154 0.9825160481476154 1.0472895454163622 0.49060325143219063 0.021658147624737254 0.7676878643432336 0.5143676851206382 0.018011399234173955 0.020809755853359056 1.5597986635204425e-07 6.806931456110348 0.06477349726874682 NLS(ph)SDEATNPISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NLSSDEATNPISR 13 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 NLS(0.904)S(0.09)DEAT(0.006)NPISR;NLS(0.969)S(0.031)DEATNPISR;NLS(0.5)S(0.5)DEATNPISR 208.38 5.1445e-10 68035000.0 149242.0 158771.0 168088.0 192995.0 208004.0 176735.0 195872.0 209840.0 181870.0 142489.0 True False 174505.72293613825 174532.73559901587 172095.85539728974 182182.11584823206 167247.10936920802 167466.7054758141 177317.58616952426 204331.9223438579 184529.50468576344 168321.1277576967 1.036742833539854 1.0369033164408272 1.02242575064627 1.082348474461796 0.9936192300824246 0.9949238560050966 1.0534481828376188 1.2139410249080544 1.0962943698392942 1.0 17.360856750321453 -7.539903272727476 24.980216094050686 1.1198095729279678 1.0285232899075634 0.26672303682382825 0.05402532773050203 250.58015100969038 367673.7596018712 0.024103497980866258 0.013920264652768412 2.884673914165606e-08 7.539903272727476 -0.09128628302040442 NLS(ph)SDEATNPISR ddPTM_PC-9_Lapatinib_30min_R1 4 NLSSDEATNPISR 13 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 NLS(0.959)S(0.041)DEATNPISR;NLS(0.696)S(0.066)DEAT(0.238)NPISR;NLS(0.5)S(0.5)DEATNPISR;NLS(0.719)S(0.281)DEATNPISR 192.78 3.1983999999999997e-06 105542000.0 268043.0 211358.0 245978.0 224479.0 227239.0 216360.0 186942.0 205146.0 232078.0 181307.0 True False 264220.65766693384 210868.6135367964 225754.63834253885 240987.93449999174 213873.24878906301 207106.78715979407 196620.94204576887 214677.83208229294 205938.9317503173 212645.67337360838 1.2425395423057146 0.9916430943145041 1.0616469865620008 1.1332839774105694 1.0057728680578317 0.9739525092331281 0.9246411597583515 1.0095565485835873 0.9684604839736962 1.0 17.698091975692797 -6.422424692060271 4.357475477415904 0.9740348405963941 1.095303329596266 0.4945944278848413 0.06288076362250428 0.21158648591888923 6.814931559706185 0.019687726035682664 0.022204020810535643 3.7807269053393247e-07 6.422424692060271 0.12126848899987186 NLS(ph)STTDDEAPR ddPTM_PC-9_AZD4547_30min_R2 2 NLSSTTDDEAPR 12 0 E9PDI4;O00515;A0A0J9YYF6;A0A0J9YVY2;A0A0J9YW63 E9PDI4 LAD1 Ladinin-1 1 NLS(0.781)S(0.073)T(0.073)T(0.073)DDEAPR;NLS(0.491)S(0.491)T(0.017)T(0.002)DDEAPR 164.7 0.00079031 114260000.0 65639.0 65868.0 89544.0 118750.0 95193.0 82638.0 62809.0 77537.0 65935.0 76981.0 True False 86510.83662398464 87158.54288105622 88356.58805298977 91374.02216921106 81977.09510078702 77470.63279633902 68398.87932284437 65555.43827300679 69420.1894910297 74285.9186211928 1.1645657512176772 1.173284849925663 1.1894123367249145 1.2300315304055922 1.1035347832045255 1.0428710344336733 0.9207516120468497 0.8824746262786967 0.934499980339814 1.0 16.180801144005308 -6.861641641520049 1.776856802060803 0.9239334813889831 1.1867537270900133 0.9084346112987343 0.03602037009622191 0.09261599895033933 0.6012099497063615 0.015652403378445753 0.013260703226887664 1.3751762348798435e-07 6.861641641520049 0.26282024570103013 NLS(ph)STTDDEAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLSSTTDDEAPR 12 0 E9PDI4;O00515;A0A0J9YYF6;A0A0J9YVY2;A0A0J9YW63 E9PDI4 LAD1 Ladinin-1 1 NLS(0.522)S(0.159)T(0.159)T(0.159)DDEAPR 115.12 0.00073759 19507000.0 8609.1 12436.0 10371.0 16262.0 20691.0 23276.0 23751.0 25511.0 25040.0 16691.0 True False 10066.450592524277 13670.563893339202 10618.28397223653 15350.892862115339 16636.74708158629 22055.365584943804 21501.13333765094 24841.363281138812 25406.16262897409 19716.94617411669 0.5105481601272998 0.6933408334443373 0.538535931399743 0.7785634107104851 0.8437790991906287 1.118599472259901 1.0904900357174192 1.2598991274698095 1.2885445040330783 1.0 14.26714849918476 -6.4989425080710514 1.1255692663120431 1.1968563622273192 0.58166577981004 0.8727306073768974 0.09546037569076071 0.14912094366306228 0.399265427902158 0.04268559203185441 0.04998577187613335 3.1699870783436087e-07 6.4989425080710514 -0.6151905824172792 NLS(ph)STTDDEAPR ddPTM_PC-9_Lapatinib_30min_R1 2 NLSSTTDDEAPR 12 0 E9PDI4;O00515;A0A0J9YYF6;A0A0J9YVY2;A0A0J9YW63 E9PDI4 LAD1 Ladinin-1 1 NLS(0.968)S(0.032)TTDDEAPR;NLS(0.797)S(0.089)T(0.089)T(0.026)DDEAPR 174.24 0.00098796 69119000.0 33137.0 30385.0 29693.0 27792.0 59289.0 92389.0 97284.0 75729.0 105867.0 102765.0 True False 32664.46030341844 30314.64539934885 27251.75615829461 29835.916391394167 55801.737586658855 88437.7378392781 102320.8895057323 79247.6458023064 93943.14363106737 120527.79332424473 0.27101185048285314 0.25151580862180206 0.2261035019946125 0.24754386991164246 0.462978173312612 0.7337538952643251 0.8489402044428699 0.6575051580768082 0.7794313746236178 1.0 16.879006340124818 -6.611921065571302 2.1414173583289062 0.79647392870237 0.245224789131691 0.9131292333988472 0.08128962339419141 0.08547619628791706 0.798609195059166 0.029823837494236245 0.030311783800589187 2.4438746944716956e-07 6.611921065571302 -0.551249139570679 down NLSES(ph)PVITK ddPTM_PC-9_AZD4547_30min_R2 1 NLSESPVITK 10 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;F5GXF5;Q12830-2 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 NLSES(1)PVITK 122.64 0.00052199 12875000.0 84799.0 71389.0 90450.0 101500.0 97892.0 97642.0 63068.0 89748.0 63883.0 99549.0 True False 111763.31807122727 94464.09816201686 89250.57390101999 78100.74315936776 84301.38553891813 91536.43030446206 68680.92982109489 75879.50880387166 67259.72496027079 96063.81981035724 1.163427795103952 0.9833473033708379 0.929075838096096 0.813008927955905 0.8775560424865498 0.9528710235046571 0.7149510602085175 0.7898864416766678 0.7001566780610061 1.0 16.55170555551905 -1.522878745281372 0.5532988565707014 0.8123954912069556 17.019756024061827 0.5606600361593295 0.08985772496748964 96.56666533763094 0.8752551601577945 0.04370992250040234 1862.3541457560304 0.02999999999992855 1.522878745281372 16.20736053285487 NLSES(ph)PVITK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NLSESPVITK 10 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;F5GXF5;Q12830-2 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 NLS(0.146)ES(0.854)PVITK;NLS(0.337)ES(0.662)PVIT(0.001)K;NLS(0.365)ES(0.635)PVITK;NLS(0.337)ES(0.662)PVIT(0.001)K 112.08 0.0015023 23269600.0 173093.0 160035.0 153544.0 168395.0 171556.0 165038.0 170522.0 145226.0 147867.0 121755.0 True False 202394.22615741534 175922.2171655308 157205.07127886306 158960.3740939558 137940.83332505048 156383.1167472056 154368.92168763076 141413.97137966592 150029.2751381197 143828.2176879503 1.4071941473719007 1.2231411887979566 1.0930057662254786 1.1052099278518226 0.9590665555233877 1.087290931230855 1.0732867595046585 0.983214376517393 1.0431143314563156 1.0 17.133987220622963 -4.267388984549834 0.829224818165378 1.0278449727592438 2.0306905981344974 0.8935283324885194 0.040905493913232296 1.482207066676258 0.43366246511790824 0.014545548545126567 1.6651745738488262 5.402702023456877e-05 4.267388984549834 1.0028456253752536 NLSES(ph)PVITK ddPTM_PC-9_Lapatinib_30min_R1 2 NLSESPVITK 10 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;F5GXF5;Q12830-2 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 NLS(0.002)ES(0.998)PVITK;NLS(0.006)ES(0.994)PVIT(0.001)K 118.73 0.00084878 26756000.0 206720.0 178173.0 182568.0 183195.0 165916.0 183537.0 148430.0 138191.0 176918.0 135205.0 True False 203772.13489219494 177760.4513654168 167557.96377285992 196667.77142060557 156157.14708340654 175687.5503556437 156114.97912643236 144611.8583510482 156991.63181086813 158575.00410066196 1.2850205241857806 1.120986579023363 1.0566480179088986 1.240219242219049 0.9847525968486144 1.1079145250667555 0.9844866787916461 0.9119461113761026 0.9900149944893666 1.0 17.27480585391489 -5.926757762980525 0.4506624695614753 0.9513592266106354 1.2675771600292791 0.5719407086927001 0.07466899222972324 1.4646450144506646 0.47277194340864487 0.06384548978026532 0.22473789178346712 1.1837016064724099e-06 5.926757762980525 0.3162179334186437 NLSFNELY(ph)PSGTLK ddPTM_PC-9_AZD4547_30min_R2 1 NLSFNELYPSGTLK 14 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 NLS(0.004)FNELY(0.795)PS(0.2)GTLK 143.96 0.00024785 14155000.0 43708.0 52502.0 59161.0 72928.0 66474.0 48550.0 54013.0 58642.0 44361.0 52879.0 True False 57606.234817122844 69472.24476743212 58376.48648488927 56115.57632636818 57245.23252476254 45514.160825071434 58820.05236295427 49580.22635910156 46705.83189522359 51027.72230511496 1.1289203635755551 1.3614608222571654 1.1440151323202932 1.0997076450097247 1.121845732844406 0.8919496847796623 1.152707777377283 0.9716331460503321 0.9153030898763407 1.0 15.638993625966156 -6.021067903974734 1.0512995139630599 0.9932857481783448 1.2481904350952393 0.5204976701298254 0.09127704987664051 0.4262898502540607 0.9609642076130844 0.03668949017067649 0.07443908052920709 9.526472015301378e-07 6.021067903974734 0.2549046869168945 NLSFNELY(ph)PSGTLK ddPTM_PC-9_Lapatinib_30min_R1 1 NLSFNELYPSGTLK 14 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 NLS(0.006)FNELY(0.801)PS(0.149)GT(0.044)LK 99.53 0.0031646 7226800.0 29929.0 24762.0 23000.0 16479.0 17216.0 21334.0 19539.0 19355.0 21897.0 14784.0 True False 29502.20697169359 24704.66511037274 21109.02878256747 17690.920632332494 16203.388727958278 20421.594551983002 20550.63381493875 20254.30395890136 19430.72927436768 17339.39470155827 1.701455412918322 1.4247709066887186 1.2174028647418949 1.0202732527187142 0.9344841043673859 1.1777570615050212 1.1851990319530523 1.1681090549880113 1.12061174042145 1.0 14.081765916154051 -5.022879475831513 1.702494944298504 1.0964783887641447 1.7638073075859535 0.8525814938175545 0.08170736563726605 0.23329209949842164 0.9505832681537113 0.02566139991024635 0.2196831575793514 9.486817022183197e-06 5.022879475831513 0.6673289188218088 NLSFNELYPS(ph)GTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLSFNELYPSGTLK 14 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 NLS(0.003)FNELY(0.246)PS(0.739)GT(0.012)LK 111.06 0.00043581 7998400.0 22595.0 21671.0 24512.0 29237.0 35409.0 27563.0 33769.0 35203.0 26260.0 19301.0 True False 26419.88722840784 23822.353661350426 25096.459042277667 27598.94567763291 28470.860635633308 26117.547758111636 30570.15585361183 34278.95855066163 26644.00282096087 22800.118513368077 1.1587609605150706 1.0448346418630674 1.1007161663463814 1.2104737815924598 1.2487154669367346 1.1455005263590405 1.3407893400066342 1.503455279434768 1.1685905406736838 1.0 14.476753702983503 -6.020858431799971 1.2947263544391314 1.2704969007071152 1.0889193313368473 0.14300747648977397 0.12873086535097522 0.6752449370522815 2.298950732553976 0.04763078234568256 0.08682034598212511 9.531068003095636e-07 6.020858431799971 -0.18157756937026792 NLSFNELYPS(ph)GTLK ddPTM_PC-9_Lapatinib_30min_R1 1 NLSFNELYPSGTLK 14 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 NLS(0.116)FNELY(0.052)PS(0.805)GT(0.027)LK 106.32 0.00088686 7140600.0 33276.0 28398.0 30636.0 17983.0 21831.0 27823.0 24203.0 25180.0 30564.0 17952.0 True False 32801.478137928956 28332.246175767912 28117.226338379893 19305.529809529417 20546.943501397378 26633.075148580796 25456.112913811477 26349.95472410933 27121.560466811607 21054.979280463616 1.5578964814448724 1.3456316341311572 1.3354193306886395 0.9169104159338941 0.9758709912605978 1.2649300098477396 1.2090305373718206 1.2514832892074508 1.2881304752447331 1.0 14.361873835346787 -5.183411068929451 1.9283874813656434 1.1463792629746516 1.5298872703207098 0.49173886151658197 0.13349288229428544 0.389672886278347 2.477240432674806 0.0404386434814141 0.19762471246216573 6.555245047335258e-06 5.183411068929451 0.38350800734605817 NLSGS(ph)TLYPVSNIPR ddPTM_PC-9_AZD4547_30min_R2 1 NLSGSTLYPVSNIPR 15 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 NLS(0.296)GS(0.496)T(0.208)LYPVSNIPR 156.72 0.0002162 7845300.0 11103.0 10622.0 14570.0 23105.0 23414.0 20027.0 14221.0 23376.0 13334.0 17543.0 True False 14633.523043253297 14055.353775468802 14376.792280131112 17778.499218691544 20163.370255058966 18774.70852407222 15486.641450272567 19763.77632704133 14038.808018099477 16928.824909673614 0.8644145781725986 0.8302616307075851 0.8492492749402708 1.0501909797963829 1.1910673282193993 1.1090379057168827 0.9148090037497557 1.1674629770521014 0.8292842588310604 1.0 14.047194213632181 -5.7593799324820125 10.065520501840563 1.048724663154987 0.8460279034976425 0.4101828151200594 0.10346824968889685 0.09197090518085312 165.54329790338423 0.028062566587219444 0.04525119235345931 1.7402837602647034e-06 5.7593799324820125 -0.20269675965734446 NLSGS(ph)TLYPVSNIPR ddPTM_PC-9_Lapatinib_30min_R1 1 NLSGSTLYPVSNIPR 15 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 NLS(0.071)GS(0.91)T(0.014)LYPVS(0.004)NIPR 122.16 5.4494e-05 8646900.0 17289.0 12676.0 12228.0 9005.8 15977.0 14921.0 14862.0 15280.0 14266.0 11149.0 True False 17042.4556895857 12646.649500811112 11222.661041445008 9668.116574468117 15037.26427199057 14282.863612549838 15631.48163967551 15989.964582382481 12659.21285236011 13076.089794891303 1.3033296617650956 0.9671583553786876 0.8582581809609161 0.7393736756262834 1.1499817229662554 1.0922885844765313 1.1954247703149434 1.2228399187522863 0.96811914348477 1.0 13.674643568940681 NLSNEELT(ph)K ddPTM_PC-9_AZD4547_30min_R2 2 NLSNEELTK 9 0 Q0JRZ9-3;Q0JRZ9 Q0JRZ9-3 FCHO2 F-BAR domain only protein 2 1 NLS(0.419)NEELT(0.581)K;NLS(0.093)NEELT(0.907)K 120.63 0.0040720999999999995 48120000.0 99299.0 98907.0 131597.0 186298.0 163618.0 142458.0 144813.0 157430.0 129767.0 165513.0 True False 130874.01645249095 130876.75351819722 129851.93779604783 143349.87437540793 140902.46495226104 133550.07873981504 157701.0764600469 133102.81088150732 136626.21869541882 159718.4402482363 0.8194045487113761 0.8194216855285277 0.8130052960336352 0.8975161174414917 0.8821928434391718 0.8361594223700778 0.987369249380009 0.8333590703405152 0.8554191894378178 1.0 17.285171362758064 -14.52287873745539 0.057193184416502826 1.4729312065443407 0.6491711685801317 0.4752478600283532 0.047200442567987125 411.2514597725242 1.717981667644323 28.38251445463076 5.112979914217776 3.000000054052826e-15 14.52287873745539 -0.823760037964209 NLSNEELT(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLSNEELTK 9 0 Q0JRZ9-3;Q0JRZ9 Q0JRZ9-3 FCHO2 F-BAR domain only protein 2 1 NLS(0.07)NEELT(0.93)K 116.9 0.0046221000000000005 40209000.0 51919.0 57202.0 76158.0 84569.0 84980.0 70323.0 75210.0 77917.0 72254.0 71426.0 True False 60707.8612530076 62880.636525151946 77973.89555082326 79830.87310639716 68328.77903403413 66635.13808343367 68085.56432675372 75871.76130988567 73310.5780588615 84374.96839209492 0.7195008473472247 0.745252267626843 0.9241354045725323 0.9461440356981101 0.809822869698827 0.789750080542569 0.8069403239401113 0.899221211643074 0.8688664358152217 1.0 16.364527436149004 -14.522878745280334 0.09562460863877828 1.5031373918276645 0.7205237296570383 0.4101836512395146 0.06655891204594391 242.27137301016091 1.585277614663483 24.72922686063988 1.468015682218485 3.000000000000026e-15 14.522878745280334 -0.7826136621706262 NLSPGAVES(ph)DVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLSPGAVESDVR 12 0 A0A3B3IU78;A0A3B3ISK1;A0A3B3ITV3;A0A3B3ISC6;A0A3B3IT15;A0A3B3IS84;P53621;P53621-2 A0A3B3IU78 COPA Coatomer subunit alpha;Xenin;Proxenin 1 NLS(0.252)PGAVES(0.748)DVR 101.43 0.0027226999999999998 19556000.0 16681.0 17949.0 13921.0 15890.0 18176.0 16703.0 17800.0 13413.0 15837.0 12839.0 True False 19504.763835232174 19730.858099191508 14252.92943568649 14999.734816075073 14614.543277507726 15827.065276048992 16113.855139159888 13060.922962248229 16068.586164339564 15166.609066531912 1.2860332688519842 1.3009406395745706 0.9397571581862927 0.9889972603813545 0.9635999196259085 1.0435467286471112 1.0624560222046113 0.8611630262871157 1.0594712432984141 1.0 13.888610945046008 -5.256689226967539 24.876634837440612 0.9884548913577907 1.2934869962365707 0.8171847341809788 0.057438458727702674 135.45296231262571 709362.94007243 0.014391693663637172 0.03554155360520384 5.53746217942042e-06 5.256689226967539 0.30503210487877996 NLSPPNCT(ph)ELQIDSCSSSEEIKK ddPTM_PC-9_AZD4547_30min_R2 1 NLSPPNCTELQIDSCSSSEEIKK 23 1 P38398-8;P38398-4;P38398;P38398-7;Q5YLB2;A0A0A0MSN1;A0A0U1RRA9 P38398-8 BRCA1 Breast cancer type 1 susceptibility protein 1 NLS(0.229)PPNCT(0.768)ELQIDS(0.002)CSSSEEIKK 50.924 0.023828 7013500.0 19303.0 17153.0 19266.0 26401.0 19296.0 18013.0 23589.0 20533.0 17125.0 23745.0 True False 25440.952472657704 22697.371804802893 19010.520251819235 20314.65734138392 16617.083473204828 16886.644262451333 25688.375302051867 17360.096651400574 18030.192538619594 22913.69477741551 1.110294639070306 0.9905592278018022 0.8296575666424879 0.8865727478139718 0.7252031431257072 0.7369673213547108 1.121092671940938 0.7576297415164689 0.7868740817997953 1.0 14.483922488007465 -4.999247993102051 2.4093691683452 0.8479346377746323 1.1211954788925924 0.3235511402359622 0.11814085007231503 0.4233532504734232 4.152185107536709 0.031605508262382564 0.19937064061519935 1.0017330598885074e-05 4.999247993102051 0.2732608411179601 NLSPPNCT(ph)ELQIDSCSSSEEIKK ddPTM_PC-9_Lapatinib_30min_R1 2 NLSPPNCTELQIDSCSSSEEIKK 23 1 P38398-8;P38398-4;P38398;P38398-7;Q5YLB2;A0A0A0MSN1;A0A0U1RRA9 P38398-8 BRCA1 Breast cancer type 1 susceptibility protein 1 NLS(0.484)PPNCT(0.516)ELQIDSCSSSEEIKK;NLS(0.018)PPNCT(0.981)ELQIDS(0.001)CSSSEEIKK 103.31 2.7662e-06 7764700.0 19318.1 21782.2 19470.5 22107.4 24089.3 25544.4 18422.4 18405.7 22468.1 18967.0 True False 19042.620351494337 21731.76465419439 17869.710648303477 23733.251944124495 22672.41473538602 24451.925558904786 19376.2217305045 19260.896015311344 19937.505978418063 22245.42067806113 0.8560242859454908 0.9769095837161076 0.8032983914719551 1.066882586200345 1.0191946946521897 1.0991891730337 0.8710206927942572 0.8658364476023066 0.8962521440685013 1.0 14.441220760796977 -5.757066507358174 24.999907565925355 0.9712653390638921 0.8885606679029177 0.20747736713452436 0.08459026227847138 222.68133609349928 1273058.8955300187 0.0252308418111478 0.04181511204918461 1.7495787396296733e-06 5.757066507358174 -0.08270467116097446 NLSPT(ph)AVINITSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLSPTAVINITSEK 14 0 Q92870;Q92870-4;H0YAJ5;G5E9Y1;Q92870-2;D6RB55 Q92870 APBB2 Amyloid beta A4 precursor protein-binding family B member 2 1 NLS(0.047)PT(0.952)AVINIT(0.001)SEK 85.522 0.016776 6600500.0 10780.0 16301.0 16048.0 14477.0 14325.0 9863.6 22325.0 13764.0 15704.0 12563.0 True False 12604.84108529482 17919.255550444068 16430.645182378925 13665.900625067274 11518.119082872921 9346.335452124586 20210.214380996895 13402.709584163484 15933.641290950853 14840.572451346714 0.8493500588753224 1.2074504274811837 1.1071436251024076 0.920847269865736 0.7761236381301252 0.6297826773708077 1.3618217523113747 0.9031127086305386 1.0736540886941963 1.0 13.857259122235288 -10.117298127571425 15.426738555507352 1.0000132075780501 0.9821806719256397 0.0007544290494359007 0.20326295457731333 0.0 0.0 0.20100194370258476 0.048750132049424216 7.633116176637392e-11 10.117298127571425 -0.017832535652410386 NLSPT(ph)AVINITSEKLEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLSPTAVINITSEKLEGK 18 1 Q92870;Q92870-4;H0YAJ5;G5E9Y1;Q92870-2;D6RB55 Q92870 APBB2 Amyloid beta A4 precursor protein-binding family B member 2 1 NLS(0.282)PT(0.718)AVINITSEKLEGK 68.57600000000001 0.008541799999999999 1993800.0 4285.2 3050.6 5470.6 4638.1 6694.3 4596.3 6373.8 5241.9 5057.1 4512.4 True False 5010.599723442056 3353.4434072869585 5601.039851366033 4378.2422939230855 5382.599970434639 4355.261936676286 5770.027521684122 5104.305679252147 5131.050520406745 5330.462399861255 0.9399934466421666 0.6291092884126233 1.0507605965876095 0.8213625696031633 1.0097810596271612 0.8170514319338689 1.0824628500961395 0.9575727763101762 0.9625901348709072 1.0 12.3800449720652 -5.755085633944469 0.5865616298513341 0.9874563042337325 0.7849009775647869 0.17748141489186897 0.11685797734103577 2.344963949015066 1.2907848449240877 0.07041398649541139 0.2827895928091513 1.7575770217294735e-06 5.755085633944469 -0.2025553266689456 NLSST(ph)TDDEAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLSSTTDDEAPR 12 0 E9PDI4;O00515;A0A0J9YYF6;A0A0J9YVY2;A0A0J9YW63 E9PDI4 LAD1 Ladinin-1 1 NLS(0.003)S(0.019)T(0.489)T(0.489)DDEAPR 123.95 0.00082364 28857000.0 16172.0 20662.0 21198.0 23610.0 41359.0 50878.0 53592.0 60153.0 51176.0 42614.0 True False 18909.60018844043 22713.18680959912 21703.440713862674 22287.208244652764 33255.0008480657 48209.868114399884 48515.37778752003 58574.0474873718 51924.35218451993 50339.580867761615 0.37564079522462773 0.4511993627691298 0.4311406718080554 0.4427372628151121 0.6606133836398865 0.9576930773627947 0.9637620526671918 1.1635783706908789 1.0314816152506592 1.0 15.619405584079349 -6.643761089089903 1.594229787591264 1.0593597757369584 0.4150545174640388 0.9688881905754503 0.05097076577658534 0.05700862644894702 0.29928618264639384 0.02079893487440004 0.020771601035471775 2.2711138768872112e-07 6.643761089089903 -0.6443052582729196 down NLSST(ph)TDDEAPR ddPTM_PC-9_Lapatinib_30min_R1 1 NLSSTTDDEAPR 12 0 E9PDI4;O00515;A0A0J9YYF6;A0A0J9YVY2;A0A0J9YW63 E9PDI4 LAD1 Ladinin-1 1 NLS(0.002)S(0.015)T(0.492)T(0.492)DDEAPR 149.32 0.00039193 6198600.0 25402.0 23572.0 28445.0 21755.0 25346.0 20678.0 20905.0 20602.0 20846.0 17858.0 True False 25039.762821843717 23517.420482259364 26106.361900875316 23354.93527255256 23855.198112153266 19793.650142772305 21987.35861104943 21559.24413129869 18498.10396188833 20944.731505710737 1.1955160568669232 1.1228322729201452 1.246440513871339 1.1150744647256359 1.138959365778882 0.9450419613818118 1.0497799222231334 1.029339723233998 0.8831864928344717 1.0 14.354299769704594 -6.673687207883719 5.161285124716494 0.9878414008112034 1.166550550857623 0.7313302890961786 0.0553116351958475 0.11417089247714489 5.078986120497018 0.018454409105087412 0.018288090912402927 2.1198873930348882e-07 6.673687207883719 0.17870915004641963 NLTANDPSQEYVAS(ph)EGEEDPEVEFLK ddPTM_PC-9_AZD4547_30min_R2 1 NLTANDPSQEYVASEGEEDPEVEFLK 26 0 Q86X95 Q86X95 CIR1 Corepressor interacting with RBPJ 1 1 NLTANDPSQEY(0.01)VAS(0.99)EGEEDPEVEFLK 132.96 2.5599e-10 2058600.0 4891.2 8170.9 7129.4 9002.7 9442.0 9633.0 6385.2 6644.9 6505.6 7681.5 True False 6446.499856719857 10811.98363434174 7034.859497732796 6927.266605328473 8131.141280783585 9030.646987186681 6953.470430228567 5618.083389611436 6849.47273455437 7412.5730230666295 0.8696710085228812 1.45860062365615 0.9490442085145798 0.9345292901361014 1.0969391135144162 1.2182877604152955 0.9380643413010009 0.7579127210118463 0.924034436253108 1.0 12.855758696731815 -7.474837553955994 8.156878734871126 0.874165023234129 1.0910526517233081 0.22514880039055019 0.16638463184027585 0.4323280241010546 68.53826990546965 0.06940972690449458 0.046214724621383214 3.350907550221465e-08 7.474837553955994 0.21688762848917909 NLTANDPSQEYVAS(ph)EGEEDPEVEFLK ddPTM_PC-9_Lapatinib_30min_R1 1 NLTANDPSQEYVASEGEEDPEVEFLK 26 0 Q86X95 Q86X95 CIR1 Corepressor interacting with RBPJ 1 1 NLTANDPSQEY(0.001)VAS(0.999)EGEEDPEVEFLK 125.05 2.5718e-12 3621900.0 72278.0 65644.0 60583.0 68270.0 66975.0 67926.0 58300.0 60343.0 72085.0 58703.0 True False 71247.30246583819 65492.00535115537 55602.09959714283 73290.80354204364 63035.6621779162 65020.9633232398 61318.48873590913 63146.756072951954 63966.028211298144 68849.73533316921 1.0348231858999453 0.9512310400938285 0.8075862503767074 1.064503780405019 0.915554168405757 0.9443894447610918 0.8906132817967157 0.9171677388065459 0.9290671620124836 1.0 16.071163488023586 NLVDNITGQR ddPTM_PC-9_Lapatinib_30min_R1 1 NLVDNITGQR 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 102.06 0.015354 0.0 22511.0 13601.0 22681.0 21774.0 23128.0 19658.0 22301.0 16989.0 23883.0 14986.0 False True 22189.98901198819 13569.507720142949 20816.255731191864 23375.332595934702 21767.6565113975 18817.27316503617 23455.636660368942 17778.370961393703 21193.045040860543 17576.310132410195 1.2624941665697231 0.7720339262289858 1.1843359370865507 1.3299340088925309 1.238465659026953 1.0706042976755217 1.3345028896092044 1.011496202983521 1.2057732755739896 1.0 14.101344610872001 -11.026287809639445 2.8533723186724287 0.9941816194763455 1.1520674716472619 0.07784608163587747 0.1610358602409524 41282922.49328373 43340622.24323853 1867269.7427134134 0.03961955714342069 9.412656072448696e-12 11.026287809639445 0.15788585217091633 NLVS(ph)PAYCTQESR ddPTM_PC-9_AZD4547_30min_R2 3 NLVSPAYCTQESR 13 0 Q9NUQ3 Q9NUQ3 TXLNG Gamma-taxilin 1 NLVS(0.66)PAY(0.008)CT(0.298)QES(0.034)R;NLVS(0.987)PAYCT(0.012)QESR;NLVS(0.999)PAYCT(0.001)QESR 98.40799999999999 0.0027665 23495800.0 42747.5 48382.0 47936.9 75569.0 68252.0 60579.0 38606.5 61551.0 44342.0 55456.0 True False 56340.315796764 64020.5353384232 47301.22538458595 58147.734579411466 58776.38791527661 56790.98555349134 42042.40370929948 52039.70725127147 46685.82759401282 53514.50231949271 1.0528046296759073 1.1963212318822902 0.8838954551457434 1.0865790030571039 1.098326348330203 1.061226080632075 0.7856263608376208 0.9724412074428647 0.8723958099299648 1.0 15.707642291421935 -7.1910808301919 12.705139714038017 0.9053392205245732 1.0638088149620437 0.41861387129530747 0.08980281192941231 1.3471055251823838 241.9005112782168 0.03330395825216657 0.02579619552135036 6.44049384921753e-08 7.1910808301919 0.15846959443747055 NLVS(ph)PAYCTQESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NLVSPAYCTQESR 13 0 Q9NUQ3 Q9NUQ3 TXLNG Gamma-taxilin 1 NLVS(1)PAYCTQESR;NLVS(0.812)PAY(0.025)CT(0.162)QES(0.001)R;NLVS(1)PAYCTQESR 124.25 0.000156 14775200.0 50829.0 43864.9 66656.0 65600.0 74153.0 69600.0 80681.0 85018.0 71809.0 55156.0 True False 59433.34578148893 48219.51737897519 68245.33183428769 61924.64467806956 59623.251961764436 65950.05347620253 73038.31160014379 82786.36758401686 72859.07077571879 65155.34618534427 0.912179111326057 0.740070005027791 1.0474248980299097 0.9504154041621621 0.9150937789841074 1.0121971156226781 1.120987238597048 1.2705997654976535 1.1182362621243713 1.0 15.991595940516945 -7.075317183079881 2.235926444790407 1.153144412220879 0.9118007118445481 0.5306316236001645 0.09404248885109608 0.23351696532105787 2.3071908820056213 0.04212322273757184 0.03145999794439454 8.407808605941931e-08 7.075317183079881 -0.2413437003763308 NLVS(ph)PAYCTQESR ddPTM_PC-9_Lapatinib_30min_R1 3 NLVSPAYCTQESR 13 0 Q9NUQ3 Q9NUQ3 TXLNG Gamma-taxilin 1 NLVS(0.55)PAY(0.181)CT(0.254)QES(0.016)R;NLVS(0.979)PAYCT(0.021)QESR;NLVS(0.995)PAY(0.001)CT(0.003)QES(0.002)R 110.22 0.00070084 21818200.0 62631.0 61739.0 81295.0 72886.0 70425.0 79212.0 76013.0 72877.0 82405.0 61184.0 True False 61737.87045488128 61596.047138732814 74611.23890777503 78246.27958056843 66282.73996087715 75824.28741219078 79948.5812055346 76263.13147056839 73123.68113688032 71759.57287744447 0.8603433378891637 0.8583669699920097 1.0397391722941385 1.0903950015728545 0.9236780167864014 1.056643516283023 1.1141172947346807 1.0627589938532018 1.0190094255684263 1.0 16.13088368271874 -5.262826534765794 9.779418226864275 1.0417032948916942 0.8591959974323446 0.6763500668070919 0.04946767002296452 0.051382855025680865 126.12447067762412 0.01328096194041063 0.0307363989148913 5.459758903965765e-06 5.262826534765794 -0.18250729745934957 NLVSPAYCT(ph)QESREEIPGGEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLVSPAYCTQESREEIPGGEAR 22 1 Q9NUQ3 Q9NUQ3 TXLNG Gamma-taxilin 1 NLVS(0.018)PAY(0.15)CT(0.416)QES(0.416)REEIPGGEAR 54.008 0.011154 8739500.0 6395.6 4434.1 5161.5 6074.0 7302.3 6654.9 7749.6 15587.0 9909.7 5446.6 True False 7478.248761142072 4874.288144053987 5284.569735097758 5733.6934721736925 5871.466734999162 6305.9053287181005 7015.501785754691 15177.85776579164 10054.610615189484 6434.025464738123 1.1622970412732816 0.7575798651664769 0.8213473453066057 0.8911518152356371 0.9125650445709172 0.9800870952839417 1.0903751973322715 2.358998709124538 1.5627247157000062 1.0 12.651505930596585 -7.561735232041045 14.490548570851816 1.7216558627432716 0.9178338310881261 0.49254472003113825 0.3242870729669238 1.5269657180019058 568.0254879416397 0.1430383994847144 0.08259189750542753 2.743246084282295e-08 7.561735232041045 -0.8038220316551455 NLVSPAYCTQES(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 NLVSPAYCTQESR 13 0 Q9NUQ3 Q9NUQ3 TXLNG Gamma-taxilin 1 NLVS(0.202)PAYCT(0.311)QES(0.488)R 71.87899999999999 0.024881 4246600.0 10609.0 10983.0 12124.0 13364.0 11705.0 14905.0 12878.0 15681.0 13980.0 11409.0 True False 10457.713714547675 10957.56953829351 11127.211519993392 14346.833140997112 11016.534912915418 14267.547895252017 13544.759827462069 16409.59650630496 12405.425184073632 13381.03044846309 0.7815327642236118 0.8188883195876793 0.8315661161410356 1.0721770043236805 0.8232949588856775 1.066251807004202 1.0122359320255327 1.226332797724836 0.9270904234059557 1.0 13.707901599089741 -5.641005335062536 0.6319679610845612 1.0595705699535014 0.7242646042507985 0.45487106158959256 0.10096474706934469 1.237834368661453 0.7504382197319447 0.05613544638001633 0.2627227918538284 2.285570726256887e-06 5.641005335062536 -0.3353059657027029 NLVSPAYCTQES(ph)REEIPGGEAR ddPTM_PC-9_AZD4547_30min_R2 1 NLVSPAYCTQESREEIPGGEAR 22 1 Q9NUQ3 Q9NUQ3 TXLNG Gamma-taxilin 1 NLVS(0.005)PAY(0.049)CT(0.156)QES(0.79)REEIPGGEAR 64.52199999999999 0.0014984000000000002 5454400.0 12244.0 7236.3 11218.0 20369.0 12373.0 11654.0 19449.0 23032.0 14369.0 16505.0 True False 16137.337308978967 9575.292461440862 11069.241990289014 15673.24174791292 10655.2225235263 10925.273537700983 21179.923322294595 19472.93362270775 15128.516005105099 15927.164973731005 1.0131958409167359 0.6011925209058602 0.694991356499775 0.984057223853907 0.6689968077244238 0.685952180172696 1.3297987028593645 1.2226239669661771 0.949856175286491 1.0 13.959201870371663 -7.2516029959150154 24.98806248027497 1.1441217118276334 0.7679270682214826 0.5346844301353575 0.15988899015542035 502.1774169650341 1275719.0758871052 0.06117719053280736 0.04680354049083351 5.602695298455726e-08 7.2516029959150154 -0.37619464360615085 NLVSPAYCTQES(ph)REEIPGGEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NLVSPAYCTQESREEIPGGEAR 22 1 Q9NUQ3 Q9NUQ3 TXLNG Gamma-taxilin 1 NLVS(0.024)PAY(0.036)CT(0.156)QES(0.784)REEIPGGEAR;NLVSPAY(0.009)CT(0.038)QES(0.953)REEIPGGEAR 81.297 0.00020517 18581500.0 13731.8 9861.5 6058.799999999999 11213.0 11170.8 17074.3 14832.599999999999 22197.1 18354.8 10828.0 True False 16056.32252458734 10840.484547616967 6203.264770126952 10584.771963036495 8981.961930258773 16178.893650412703 13427.548749275453 21614.449644771517 18623.204226129958 12791.030685599162 1.255279806549477 0.8475067267113802 0.4849698919971261 0.8275151724054112 0.7022078322719649 1.2648623905365015 1.049762843927262 1.6898129772377326 1.455958060291183 1.0 13.642844899053761 -7.029224128938082 1.798813237659608 1.3824710029515388 0.8070454430337304 0.41907188800830486 0.2634876597507251 0.3172594975383944 2.057952980305546 0.12481469884226196 0.09320284230445136 9.349230583179307e-08 7.029224128938082 -0.5754255599178084 NLVSPAYCTQES(ph)REEIPGGEAR ddPTM_PC-9_Lapatinib_30min_R1 4 NLVSPAYCTQESREEIPGGEAR 22 1 Q9NUQ3 Q9NUQ3 TXLNG Gamma-taxilin 1 NLVS(0.018)PAY(0.021)CT(0.045)QES(0.916)REEIPGGEAR;NLVS(0.02)PAY(0.137)CT(0.153)QES(0.69)REEIPGGEAR;NLVS(0.055)PAY(0.196)CT(0.112)QES(0.637)REEIPGGEAR;NLVS(0.001)PAY(0.004)CT(0.046)QES(0.949)REEIPGGEAR 69.845 0.0009186 59684200.0 36674.8 37730.9 37025.7 27910.8 51794.9 41381.6 51932.1 44338.8 38054.6 52070.3 True False 36151.81062666541 37643.53641922958 33981.58986933515 29963.453339699372 48748.425814691385 39611.80543322112 54620.89003228313 46398.94251474742 33768.49021529674 61070.58197568654 0.5919676783341968 0.6163939363508317 0.5564314072340742 0.49063644672042656 0.7982309032866125 0.6486233494383825 0.8943895451009266 0.7597592984003295 0.5529420078023929 1.0 15.898189973042982 -6.268936925351671 24.849937099157962 0.7632303809336669 0.5670795523742314 0.4309864535216942 0.11868610154377988 547.0410307648941 1813114.823872057 0.035556570670414255 0.04110756108203561 5.383479636680595e-07 6.268936925351671 -0.19615082855943555 NLVTEDVMR ddPTM_PC-9_Lapatinib_30min_R1 1 NLVTEDVMR 9 0 P06744-2;P06744;A0A2U3TZU2;K7EQ48;A0A0J9YXP8;A0A2R8Y6C7;A0A0J9YYH3;A0A0J9YX90;K7EPY4;K7ERC6;K7EP41;K7ENA0;A0A0J9YYI8;K7EIL4;A0A0J9YXM3;K7ELR7;A0A2R8YF08;K7ERK8;A0A0J9YXH9 P06744-2 GPI Glucose-6-phosphate isomerase 0 93.598 0.028257 2622400.0 18559.0 18856.0 18303.0 17745.0 19936.0 21068.0 16589.0 14502.0 21382.0 18091.0 False True 18294.34525669623 18812.34009050919 16798.197991623154 19050.026495584694 18763.403675684043 20166.970751906723 17447.8972493996 15175.815862153831 18973.733997558105 21218.005245257762 0.8622085368173348 0.8866215213474774 0.7916954396727545 0.8978236302322711 0.8843151586965357 0.9504649715558937 0.8223156252305677 0.7152329206604205 0.8942279812942712 1.0 14.37300141101204 NLVYDQS(ph)PNR ddPTM_PC-9_AZD4547_30min_R2 1 NLVYDQSPNR 10 0 Q9NXR1;Q9NXR1-1;I3L533;I3L2R9;I3L2T8 Q9NXR1 NDE1 Nuclear distribution protein nudE homolog 1 1 NLVYDQS(1)PNR 120.55 0.00069658 18950000.0 67731.0 83787.0 105650.0 130100.0 105090.0 98089.0 89255.0 113890.0 78806.0 106200.0 True False 89268.04910768164 110869.50920591259 104249.01196951637 100107.45502496295 90500.0674854422 91955.47932379889 97198.52209015367 96290.9174318419 82971.52427436244 102481.97032476407 0.8710610151697153 1.0818440439285906 1.0172424636172839 0.9768299214751989 0.8830828212869896 0.897284459231152 0.9484450950946081 0.9395888576956238 0.809620697293648 1.0 16.64501059284064 -6.109745889468208 4.8535224831732116 0.9112871124773237 0.998964036464381 0.22234567219173818 0.06708248404093325 0.3044180154170117 11.044117158609353 0.019366002299940007 0.025503888046743906 7.767014403523926e-07 6.109745889468208 0.08767692398705729 NLVYDQS(ph)PNR ddPTM_PC-9_Lapatinib_30min_R1 1 NLVYDQSPNR 10 0 Q9NXR1;Q9NXR1-1;I3L533;I3L2R9;I3L2T8 Q9NXR1 NDE1 Nuclear distribution protein nudE homolog 1 1 NLVYDQS(1)PNR 107.39 0.0021795 16493000.0 126550.0 98032.0 110500.0 98656.0 101460.0 90986.0 79817.0 83709.0 94564.0 75529.0 True False 124745.37379357219 97805.01292706806 101415.1165423352 105911.49134676826 95492.32227803483 87094.74087872519 83949.53371241952 87598.42573472855 83913.20651693417 88584.08701393341 1.4082142515500662 1.1040923513913317 1.1448457613655103 1.1956040290860526 1.0779850591338693 0.9831872045486684 0.9476818754051738 0.9888731564276343 0.9472717882584875 1.0 16.43475994009072 -1.5228787452804244 0.3131415852064847 0.94898727278736 4.660649967163873 0.783055367581531 0.06336561584602507 26.88700011420486 0.38392307968263834 0.06464029952653923 56.7281779197196 0.029999999999994 1.5228787452804244 3.7116626943765127 NLYIISVK ddPTM_PC-9_Lapatinib_30min_R1 1 NLYIISVK 8 0 P62829;C9JD32;J3KT29;B9ZVP7 P62829 RPL23 60S ribosomal protein L23 0 91.853 0.038764 9823000.0 55389.0 39327.0 57517.0 44431.0 51423.0 39700.0 52459.0 41579.0 36923.0 41497.0 False True 54599.142702901445 39235.94074774366 52788.174282040614 47698.60395747101 48398.40024150787 38002.12354522008 55175.07033614168 43510.91213160215 32764.34292357302 48669.7011587232 1.1218302435192886 0.806167693937264 1.0846208837380389 0.9800471920284611 0.9944256711926266 0.7808168663556476 1.1336636351269749 0.8940040948618723 0.6731979474605954 1.0 15.570736295769487 -7.998089536569868 24.999109823862234 0.8189329690257564 0.9778022407139231 0.17017584768961236 0.1337961367828296 86.39494540971545 1130515.008838191 0.06869402442228852 0.032638603584745816 1.0044086944390505e-08 7.998089536569868 0.15886927168816667 NLYPS(ph)SSPYTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NLYPSSSPYTR 11 0 Q9Y2Z0-2;Q9Y2Z0 Q9Y2Z0-2 SUGT1 Suppressor of G2 allele of SKP1 homolog 1 NLYPS(0.543)S(0.229)S(0.229)PYTR 100.09 0.0042935000000000004 29156000.0 158610.0 146400.0 135510.0 180210.0 180540.0 152340.0 161240.0 141070.0 149760.0 102990.0 True False 185459.54030970446 160933.6244761062 138741.07232453657 170113.4179487031 145164.48301723425 144351.02222075695 145966.179923491 137367.06197601993 151949.95668191573 121661.2717316086 1.5243925833591343 1.3228007745236672 1.140388147763299 1.3982544775956525 1.1931856452846803 1.1864993696531725 1.1997752271199362 1.1290944112359695 1.248959134810999 1.0 16.892510464404573 -1.5228787452803376 0.20877712061358605 1.077336847821282 2.8813585866648963 0.5924460043379961 0.09006490528791408 39.745966244135126 0.49304715306982977 0.15343345815603962 23.763949597601947 0.029999999999999995 1.5228787452803376 1.8040217388436144 NLYPS(ph)SSPYTR ddPTM_PC-9_Lapatinib_30min_R1 1 NLYPSSSPYTR 11 0 Q9Y2Z0-2;Q9Y2Z0 Q9Y2Z0-2 SUGT1 Suppressor of G2 allele of SKP1 homolog 1 NLYPS(0.302)S(0.302)S(0.302)PYT(0.093)R 82.505 0.039827999999999995 0.0 19286.0 26927.0 24816.0 17751.0 21105.0 18135.0 18961.0 12661.0 22402.0 16446.0 True False 19010.978103380752 26864.652185889958 22775.72427253019 19056.4677556001 19863.64539402647 17359.408324749766 19942.707803114467 13249.276281252922 19878.85085648194 19288.66918708246 0.9856034088713762 1.392768569222033 1.1807825647081447 0.987961770237738 1.0298090138499065 0.8999795764227885 1.0339079181507251 0.686894266926715 1.0305973244538156 1.0 14.235465988284924 -5.820512872106767 2.8690849016741877 0.9368415536271493 1.212971164023518 0.38989528355953973 0.13372495388069303 0.23510346721183817 3.927413296161284 0.038056741232034334 0.06427349144476403 1.5117748910176223e-06 5.820512872106767 0.27612961039636863 NLYPSS(ph)SPYTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NLYPSSSPYTR 11 0 Q9Y2Z0-2;Q9Y2Z0 Q9Y2Z0-2 SUGT1 Suppressor of G2 allele of SKP1 homolog 1 NLYPS(0.116)S(0.426)S(0.426)PYT(0.031)R;NLYPS(0.123)S(0.438)S(0.438)PYT(0.001)R 107.39 0.0023159 12608500.0 64611.0 64938.0 70162.0 68049.0 87747.0 61236.0 68722.0 64943.0 58953.0 49816.0 True False 75548.366174581 71384.61547970903 71834.92817086683 64236.43514783474 70553.60524710995 58024.67636018301 62212.15465580596 63238.31506279636 59815.07609688142 58847.246456760986 1.2838046080897165 1.2130493740630683 1.2207016045117551 1.0915792839182976 1.198927893745214 0.9860219441672199 1.057180384837843 1.0746180810560404 1.016446472832532 1.0 15.84468729071607 -5.390754660121065 0.4128501646783376 1.008236830913091 1.3902450710506693 0.7728260833420011 0.04799879122557184 1.5761914518060967 0.3061398980694512 0.04027463904163858 0.2833037402808951 4.066730003501471e-06 5.390754660121065 0.3820082401375784 NLYPSSS(ph)PYTR ddPTM_PC-9_AZD4547_30min_R2 2 NLYPSSSPYTR 11 0 Q9Y2Z0-2;Q9Y2Z0 Q9Y2Z0-2 SUGT1 Suppressor of G2 allele of SKP1 homolog 1 NLYPS(0.062)S(0.212)S(0.727)PYTR;NLYPS(0.054)S(0.2)S(0.745)PYT(0.002)R 119.03 0.0019164000000000002 0.0 27319.0 29631.0 34872.0 54317.0 45742.0 49207.0 40955.0 45831.0 37298.0 38259.0 True False 36005.873729499865 39208.64128421351 34409.574495039975 41795.05483928451 39391.51286439342 46130.07851121092 44599.91565965217 38748.87204160814 39269.496134623856 36919.5640551333 0.9752518658056475 1.062001740477267 0.9320146479426175 1.1320571060067357 1.0669549836928918 1.2494751682962246 1.2080293145674617 1.04954847201725 1.0636500494962866 1.0 15.172097897343253 -5.777491979928938 24.93037809618902 1.120131407271431 0.9969806490061573 0.3332325842128001 0.07677886014057508 257.8355567890662 400428.890330894 0.02237044303916335 0.03329832009319066 1.6691986318440957e-06 5.777491979928938 -0.12315075826527366 NLYPSSS(ph)PYTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NLYPSSSPYTR 11 0 Q9Y2Z0-2;Q9Y2Z0 Q9Y2Z0-2 SUGT1 Suppressor of G2 allele of SKP1 homolog 1 NLYPS(0.056)S(0.204)S(0.739)PYT(0.001)R;NLYPS(0.052)S(0.197)S(0.751)PYT(0.001)R 134.18 5.9093999999999994e-05 38410300.0 117513.0 123864.0 136288.0 129551.0 131221.0 126231.0 117254.0 97194.0 91864.0 91117.0 True False 137405.62991245402 136160.3993313417 139537.62279511837 122292.67748000915 105509.18702782998 119611.22414302471 106146.85227455376 94642.76048555523 93207.33721038653 107635.79081822486 1.2765793688876632 1.265010442124118 1.2963868406074077 1.1361711244035622 0.980242596126912 1.1112588408907957 0.9861668824807018 0.8792870825410459 0.8659511534392395 1.0 16.715798353913065 -6.250240161469284 0.7341874322404008 0.9175701345110956 1.317795815408378 0.8298666220075418 0.06324234393715544 0.30796197073038073 0.3560906366162721 0.039672401896135676 0.07177700157661925 5.620304407793015e-07 6.250240161469284 0.4002256808972824 NMAPGAVCS(ph)PGESK ddPTM_PC-9_AZD4547_30min_R2 5 NMAPGAVCSPGESK 14 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 NMAPGAVCS(0.964)PGES(0.036)K;NMAPGAVCS(0.733)PGES(0.267)K;NMAPGAVCS(0.928)PGES(0.072)K;NMAPGAVCS(0.94)PGES(0.06)K;NMAPGAVCS(0.893)PGES(0.107)K 139.49 9.557e-05 64579300.0 144104.0 138434.0 131851.0 163271.0 155150.0 166804.0 136037.0 174096.0 141730.0 141686.0 True False 189926.07445059618 183180.08327558346 130102.56959008696 125631.39346180441 133610.1005839413 156373.71951112727 148144.02946141097 147193.46352808853 149221.55845247043 136725.61626586167 1.3891038097885529 1.3397641808349323 0.9515595770810332 0.9188577597450017 0.9772133725412341 1.1437046237704283 1.0835133423231116 1.0765609806568524 1.0913943014329555 1.0 17.060924039235317 -5.220324851101753 7.6809353435971905 1.0332136058752133 1.3670852518214776 0.7981443787622715 0.06720004007975237 0.13330622077797868 21.8722044686283 0.019530165891572564 0.05154796093870922 6.0210904165228326e-06 5.220324851101753 0.3338716459462643 NMAPGAVCS(ph)PGESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NMAPGAVCSPGESK 14 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 NMAPGAVCS(0.992)PGES(0.008)K;NMAPGAVCS(0.997)PGES(0.003)K;NMAPGAVCS(0.537)PGES(0.463)K 91.355 0.0048565 24646300.0 85577.0 84659.0 65184.0 83504.0 89111.0 75178.0 107960.0 86890.0 75921.0 78784.0 True False 100063.49587720538 93063.3860281603 66738.23377169664 78825.54160362075 71650.33923866609 71235.53333669461 97733.2472372868 84609.22956756495 77031.20099657935 93066.91554619893 1.0751779543777114 0.9999620754806591 0.7170994480693562 0.8469770502331875 0.7698798097923258 0.7654227382375524 1.0501395330843588 0.9091225283550357 0.8276969376764254 1.0 16.50598077332325 -9.910039271264623 15.27269433605979 0.9999982120038698 0.8806775708580091 0.07912698745855518 0.11740781899920232 0.0 0.0 0.11992651559164152 0.029086452417448314 1.2301575282612604e-10 9.910039271264623 -0.11932064114586072 NMAPGAVCS(ph)PGESK ddPTM_PC-9_Lapatinib_30min_R1 6 NMAPGAVCSPGESK 14 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 NMAPGAVCS(0.832)PGES(0.168)K;NMAPGAVCS(0.844)PGES(0.156)K;NMAPGAVCS(0.956)PGES(0.044)K;NMAPGAVCS(0.996)PGES(0.004)K;NMAPGAVCS(1)PGESK;NMAPGAVCS(0.878)PGES(0.122)K 171.15 0.00023595 83640000.0 155281.0 266740.0 260868.0 258812.0 385979.0 367577.0 416116.0 371312.0 361945.0 358491.0 True False 153066.6644649522 266122.3799184572 239420.44001960053 277845.8978515229 363276.47408391075 351856.5885738376 437660.4504087744 388564.5110610996 321178.9426501811 420455.6916907684 0.3640494527483476 0.6329379888955853 0.5694308455115088 0.6608208744522588 0.864006555894334 0.8368458211587649 1.0409193145865643 0.9241509123079639 0.7638829703045092 1.0 18.681594249361808 -5.906791021518465 0.8530718244994004 0.9321696682759011 0.4413325527580898 0.7950659048211267 0.09042017781804036 0.33320892660367674 0.47009509005595407 0.042001793856444224 0.11253857118795062 1.239392827413305e-06 5.906791021518465 -0.4908371155178113 NMAPGAVCSPGES(ph)K ddPTM_PC-9_AZD4547_30min_R2 3 NMAPGAVCSPGESK 14 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 NMAPGAVCS(0.488)PGES(0.512)K;NMAPGAVCS(0.018)PGES(0.982)K;NMAPGAVCS(0.347)PGES(0.653)K 128.45 2.258e-05 56019000.0 99485.0 94601.0 88143.0 101099.0 109038.0 116051.0 90348.0 114162.0 97391.0 102562.0 True False 131119.16058345113 125178.92322661667 86974.1662283869 77792.18751397947 93899.95583288283 108794.31262431224 98388.79697273232 96520.88608178026 102538.88943233286 98971.33559744316 1.324819552974068 1.2647997773392738 0.8787813734488372 0.7860072519420377 0.9487591055132598 1.0992507271683505 0.9941140672580164 0.9752408159304844 1.0360463341567945 1.0 16.5947231271722 -5.198182986947037 6.076618367849385 0.9629966232106171 1.3026889664982688 0.724395355090335 0.08150932209386222 0.12681645314792123 9.312480826369885 0.023406038866900295 0.06346996233244066 6.336026909382669e-06 5.198182986947037 0.33969234328765174 NMAPGAVCSPGES(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NMAPGAVCSPGESK 14 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 NMAPGAVCS(0.366)PGES(0.634)K;NMAPGAVCS(0.476)PGES(0.524)K;NMAPGAVCS(0.115)PGES(0.885)K 120.59 7.4439e-05 39295100.0 115920.0 118328.0 84626.0 104519.0 128374.0 100428.0 136891.0 102646.0 95126.0 98977.0 True False 135542.966475638 130074.82183749114 86643.80478589228 98663.13928517011 103220.03624046955 95161.37888661014 123923.69347498535 99951.65126242679 96517.03778928862 116920.74659849894 1.1592721601503881 1.1125042015354447 0.7410473103069001 0.8438462989290968 0.8828205365034396 0.8138964354494794 1.0598948183296695 0.854866686796456 0.8254911176775511 1.0 16.835171421065233 -5.14682527667763 6.367256871361166 0.8761602165693596 1.1460197195185855 0.5856865456178559 0.08708401211224638 0.15504397767111708 7.53806717461725 0.022162679142722748 0.06046023818926858 7.131398795177398e-06 5.14682527667763 0.2698595029492259 NMAPGAVCSPGES(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 NMAPGAVCSPGESK 14 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 NMAPGAVCS(0.331)PGES(0.669)K 89.46600000000001 0.0046786 19292000.0 14315.0 21584.0 24165.0 24342.0 31351.0 30911.0 38525.0 31885.0 29935.0 28477.0 True False 14110.865474950504 21534.023574117018 22178.246979597545 26132.191882531577 29506.995818437517 29589.00858706038 40519.635995727265 33366.493501915254 26563.405070475266 33399.21150678266 0.4224909762341213 0.644746465638685 0.6640350469080272 0.7824194255970591 0.8834638450205713 0.8859193751041545 1.2131913948776485 0.9990203958898622 0.7953303048810243 1.0 15.027526423306199 -5.571740091874517 0.717670227124399 1.001369616072561 0.3960805417547122 0.7478392164458028 0.10553320249505292 0.6543209480516925 0.5073243525045079 0.05451632149748776 0.2737791506090196 2.680772181310559e-06 5.571740091874517 -0.6052890743178487 down NMAPSQQS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 1 NMAPSQQSPVR 11 0 H0Y6B5;B7Z836;E7EW77;E7EP65;A0A0C4DG21;F8WAL6;Q9NYB9-3;Q9NYB9-2;Q9NYB9-4;Q9NYB9;H7C3Q7 H0Y6B5 ABI2 Abl interactor 2 1 NMAPS(0.147)QQS(0.853)PVR 71.933 0.028492 7149600.0 36461.0 38085.0 33135.0 33265.0 37521.0 31734.0 33734.0 30326.0 34540.0 27649.0 True False 35941.05945387151 37996.81652243541 30410.768204798846 35711.419068786985 35314.08854912423 30376.810795567097 35480.58145827033 31735.05667050596 30649.74147767546 32428.0928100233 1.108330966746289 1.171725292172929 0.9377908341066264 1.1012494406624134 1.0889967768381645 0.9367436738733471 1.0941309951877136 0.9786285260876296 0.9451601627401854 1.0 14.984956556768038 -1.5228787475923689 0.2612653306621319 0.9792149683117573 2.049641982238846 0.2961289062063803 0.06838196646537563 63.95952995839741 0.884037936992353 0.08209375392995356 30.531223418403055 0.029999999840290538 1.5228787475923689 1.0704270139270888 NMGGPYGGGNYGPGGS(ph)GGSGGYGGR ddPTM_PC-9_AZD4547_30min_R2 2 NMGGPYGGGNYGPGGSGGSGGYGGR 25 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 NMGGPYGGGNYGPGGS(0.703)GGS(0.297)GGYGGR;NMGGPYGGGNYGPGGS(0.779)GGS(0.221)GGYGGR 146.34 3.2644e-07 65606000.0 49311.0 50664.0 59791.0 86380.0 72106.0 69203.0 58230.0 72517.0 55838.0 60383.0 True False 64990.87226748299 67040.14721148102 58998.13227325462 66466.42555769636 62095.32654015896 64875.725470183745 63412.35719354277 61311.16392488267 58789.48268446372 58269.00954915478 1.115359138079355 1.150528346546324 1.0125130447512543 1.140682260981738 1.065666415485857 1.1133830139236474 1.0882690075596555 1.052208788157993 1.0089322461345405 1.0 15.83044116765588 -8.029666600240253 1.8072766845269594 0.9998222151361575 1.098833174622325 0.5145448138484361 0.03673470823014208 0.29272987051926525 1.717148577152041 0.030945268339788286 0.01010887063878653 9.339710177574488e-09 8.029666600240253 0.09901095948616745 NMGGPYGGGNYGPGGS(ph)GGSGGYGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NMGGPYGGGNYGPGGSGGSGGYGGR 25 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 NMGGPY(0.032)GGGNY(0.078)GPGGS(0.791)GGS(0.098)GGYGGR;NMGGPYGGGNY(0.001)GPGGS(0.828)GGS(0.171)GGYGGR;NMGGPYGGGNYGPGGS(0.541)GGS(0.459)GGYGGR 140.84 2.8664e-09 53167700.0 76934.0 69240.0 65363.0 87704.0 99612.0 78692.0 83205.0 72881.4 71546.0 62602.4 True False 89957.40668423666 76113.68960878135 66921.50181055794 82790.22922020439 80093.74367072496 74565.2529906512 75323.22004796627 70968.34047422624 72592.22489826592 73951.71955967427 1.216434279281996 1.0292348854357944 0.9049350334113138 1.1195172974091294 1.083054513777661 1.0082964052036931 1.0185458904330857 0.9596577455776314 0.9816164563920475 1.0 16.174296073477876 -4.76784406300598 5.2782269992684565 1.0119500877284442 1.2266649913780285 0.5431834413160975 0.05653768790621383 0.12475875375735254 10.119970380416289 0.014796918018424704 0.09772104802641406 1.7066950818607617e-05 4.76784406300598 0.21471490364958434 NMGGPYGGGNYGPGGS(ph)GGSGGYGGR ddPTM_PC-9_Lapatinib_30min_R1 3 NMGGPYGGGNYGPGGSGGSGGYGGR 25 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 NMGGPYGGGNYGPGGS(0.682)GGS(0.318)GGYGGR;NMGGPYGGGNYGPGGS(0.507)GGS(0.493)GGYGGR;NMGGPYGGGNYGPGGS(0.64)GGS(0.36)GGYGGR 201.85 5.300599999999999e-26 68028800.0 121791.0 104826.0 123113.0 113592.0 111289.0 109476.0 101980.0 106499.0 114865.0 89773.0 True False 120054.23800626613 104583.28183749017 112991.124369923 121945.93461180382 104743.1998225924 104793.9666810205 107260.02540802765 111447.33233371392 101927.69411792685 105290.14343499651 1.1402229505023382 0.9932865359050181 1.0731405683731534 1.1581894623126825 0.9948053673918511 0.9952875289387145 1.018709082434172 1.0584783028861453 0.9680649184494126 1.0 16.68401086157896 -6.302310765112198 24.997834955163626 1.0089255121733018 1.0829247515764062 0.4405749416839698 0.046652363520699944 551.4653267960421 337287.10742826224 0.014547220172489068 0.016495110942137504 4.985276318138508e-07 6.302310765112198 0.07399923940310438 NMGGPYGGGNYGPGGSGGS(ph)GGYGGR ddPTM_PC-9_AZD4547_30min_R2 4 NMGGPYGGGNYGPGGSGGSGGYGGR 25 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 NMGGPYGGGNYGPGGS(0.15)GGS(0.85)GGYGGR;NMGGPYGGGNYGPGGS(0.028)GGS(0.972)GGYGGR;NMGGPYGGGNYGPGGS(0.03)GGS(0.97)GGYGGR;NMGGPYGGGNYGPGGS(0.401)GGS(0.599)GGYGGR 206.99 7.8393e-31 82066900.0 100580.5 96515.9 107552.2 160443.0 140503.0 131020.0 100418.0 131662.9 108822.7 123979.6 True False 132563.00679563498 127712.77720370633 106125.98755464081 123455.34516963972 120996.58370831801 122827.29868796836 109355.00746455732 111317.42411745421 114574.84575605477 119639.11194045334 1.1080239952099789 1.0674834937530413 0.8870509470804309 1.031897873256413 1.0113463878647002 1.0266483652026925 0.9140406150706417 0.9304434169726954 0.957670479977157 1.0 16.868329581181413 -7.25048630447368 24.602413705483027 0.944742245860612 1.0179605438298465 0.2711327070704601 0.05690549345634187 820.8804977492783 1843834.8940227225 0.02274447402161457 0.01743911650399863 5.6171199172845485e-08 7.25048630447368 0.07321829796923451 NMGGPYGGGNYGPGGSGGS(ph)GGYGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NMGGPYGGGNYGPGGSGGSGGYGGR 25 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 NMGGPYGGGNYGPGGS(0.091)GGS(0.909)GGYGGR;NMGGPYGGGNYGPGGS(0.237)GGS(0.763)GGYGGR 195.31 3.5481000000000003e-25 62085000.0 45762.0 48271.0 40750.0 46068.0 51294.0 46491.0 52869.0 47747.0 43933.0 34213.0 True False 53508.602759300724 53063.02586807468 41721.63454523558 43486.95931447114 41243.30891705997 44052.930117271964 47860.865581586746 46493.691842128246 44575.43701192968 40415.546070041 1.3239609002577668 1.3129360117048854 1.0323164871490567 1.0759958368274258 1.020481298102083 1.0899996264043372 1.1842191986876252 1.1503912816507216 1.1029279904984954 1.0 15.302622720150913 -5.251677335120048 24.700114948597722 1.088931514654595 1.3184485078525965 0.7538018013137832 0.05392745606731645 298.1205282422862 754305.6129048006 0.01487939979427591 0.03832592562530585 5.6017363540360265e-06 5.251677335120048 0.22951699319800145 NMGGPYGGGNYGPGGSGGS(ph)GGYGGR ddPTM_PC-9_Lapatinib_30min_R1 3 NMGGPYGGGNYGPGGSGGSGGYGGR 25 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 NMGGPYGGGNYGPGGS(0.383)GGS(0.617)GGYGGR;NMGGPYGGGNYGPGGSGGS(1)GGYGGR;NMGGPYGGGNYGPGGSGGS(1)GGYGGR 308.32 1.4897999999999995e-161 84777000.0 83603.0 71968.0 82387.0 70766.0 77248.0 78710.0 70755.0 66352.0 71939.0 57604.0 True False 82410.80588908751 71801.3625177008 75613.45888301678 75970.36770845583 72704.4245154113 75343.7567819715 74418.3476931262 69434.9561498848 63836.472268746205 67560.77464749466 1.2198025602736857 1.0627670107741045 1.119191709650131 1.1244744913722362 1.076133672160424 1.1151997172188353 1.1015022856296666 1.0277406751501723 0.944874782768842 1.0 16.043898249632086 -7.884532554284035 2.64675655786097 0.9731733900608635 1.1149385579599222 0.6743990487909028 0.0413272161868287 0.1600979918634944 2.192534608663829 0.027338680542456334 0.01086148479297759 1.3045701756869975e-08 7.884532554284035 0.1417651678990588 NMGGPYGGGNYGPGGSGGSGGYGGR ddPTM_PC-9_Lapatinib_30min_R1 3 NMGGPYGGGNYGPGGSGGSGGYGGR 25 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;; 222.11 1.3133999999999998e-100 10515000.0 34204.5 36472.1 26870.9 28232.8 34892.7 25328.7 38968.5 40525.4 37078.9 32759.5 False True 33716.7375576629 36387.65109328913 24661.67832667358 30309.134293859894 32840.379987687615 24245.450545083506 40986.09825566512 42408.35802924624 32902.68382387324 38421.9359257101 0.8775387482519142 0.9470540777446946 0.6418645425456341 0.7888497433461827 0.8547299660065389 0.6310314657742069 1.0667369373295739 1.1037538064517103 0.856351535422148 1.0 15.229642591943248 -7.280546555467328 24.99024864486914 1.0153567358564992 0.7934410819622473 0.4836002780900909 0.10944020547766226 730.4210827452845 955312.7768156066 0.0461607304145245 0.0311766291355583 5.241474104819295e-08 7.280546555467328 -0.22191565389425194 NMGLS(ph)PPASSTSTSSTCR ddPTM_PC-9_AZD4547_30min_R2 1 NMGLSPPASSTSTSSTCR 18 0 Q9HC52;C9JM54;C9J6K3 Q9HC52 CBX8 Chromobox protein homolog 8 1 NMGLS(0.624)PPAS(0.082)S(0.082)T(0.082)S(0.026)T(0.026)S(0.026)S(0.026)T(0.026)CR 67.252 0.011588 4872000.0 23648.0 19980.0 21519.0 28061.0 25513.0 24113.0 24090.0 23072.0 23076.0 22674.0 True False 31167.572091043327 26438.144269804805 21233.643999735177 21591.969988128258 21970.960336436303 22605.210298145168 26233.963331486288 19506.752541816295 24295.750249412304 21880.190161428487 1.4244653205065425 1.208314190815915 0.9704506150575841 0.9868273460525805 1.0041485094205365 1.0331359157012623 1.1989824191625562 0.891525731627497 1.1103994101587877 1.0 14.417337656242884 -4.938172623983006 2.7447664455619827 1.0255730927650395 1.441054299561661 0.7165267386258104 0.07909227570277498 0.16851089443127834 2.1798389517954706 0.020251422616913144 0.13656359379349134 1.1529948726996634e-05 4.938172623983006 0.4154812067966216 NMPGLSAATLAS(ph)LGGTSSRR ddPTM_PC-9_AZD4547_30min_R2 1 NMPGLSAATLASLGGTSSRR 20 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3;C9JTC6;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 NMPGLSAATLAS(0.875)LGGT(0.099)S(0.02)S(0.006)RR 130.81 1.7060999999999998e-05 1741700.0 10011.0 8061.4 13355.0 16418.0 13979.0 10811.0 13732.0 12450.0 8084.1 8754.4 True False 13194.28975826432 10667.089900730945 13177.903973998016 12633.08375557143 12038.257145104191 10134.986460964927 14954.12139759109 10526.138572538697 8511.409021982749 8447.911120631981 1.5618405035110343 1.2626896458083179 1.5599008779595431 1.4954091698145564 1.4249980821535466 1.1997032540047292 1.7701560994254855 1.246004890703827 1.0075164026283006 1.0 13.044378941032459 -7.999216638657478 24.99971667063157 1.0447589339159908 1.4565341234137472 0.5993438067015397 0.15151461971870028 17.11278114094266 546134.0628616001 0.08109897866222651 0.03842191735351141 1.0018053838963825e-08 7.999216638657478 0.4117751894977564 NMPGLSAATLAS(ph)LGGTSSRR ddPTM_PC-9_Lapatinib_30min_R1 1 NMPGLSAATLASLGGTSSRR 20 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3;C9JTC6;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 NMPGLSAATLAS(0.336)LGGT(0.221)S(0.221)S(0.221)RR 79.94 0.00069753 3026100.0 13447.0 14472.0 17163.0 14364.0 14079.0 10543.0 18828.0 12601.0 10855.0 8997.9 True False 13255.24331412221 14438.490973157022 15751.924391095909 15420.376476899335 13250.90090037899 10092.100466933385 19802.821713888472 13186.488462212148 9632.395591782488 10553.175026051887 1.2560431606033176 1.36816559353121 1.4926241962452278 1.4612073085902704 1.255631681239761 0.956309399021595 1.876479984933693 1.2495280737464871 0.9127485868474335 1.0 13.365389492720043 -8.138258062466685 4.782360177752188 0.9636712131942424 1.3781618836310408 0.36418082626441894 0.2200645644612639 0.2435480603266339 8.1862085068986 0.15951432575550525 0.056766192580311604 7.2734747838421434e-09 8.138258062466685 0.4144906704367983 NMPGLSAATLASLGGT(ph)SSR ddPTM_PC-9_AZD4547_30min_R2 3 NMPGLSAATLASLGGTSSR 19 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3;C9JTC6;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 NMPGLSAATLAS(0.001)LGGT(0.562)S(0.139)S(0.299)R;NMPGLSAATLAS(0.001)LGGT(0.813)S(0.155)S(0.031)R;NMPGLSAATLASLGGT(0.388)S(0.388)S(0.224)R 118.44 0.0003285 170855000.0 131299.2 127686.2 173361.2 224620.7 178979.5 166104.0 174918.6 195472.6 153478.0 160653.8 True False 173049.61440698267 168958.2671102676 171062.3172158042 172837.86797022045 154131.28583605206 155717.4906217849 190486.01653777115 165266.801183488 161590.5337484529 155029.35936121084 1.1162376927829878 1.0898469025896127 1.1034188486661896 1.114871845451652 0.9942070745253723 1.00443871575945 1.2287093059189391 1.0660355036262803 1.0423221408788437 1.0 17.2421819324772 -14.522878728846733 0.23560471608428912 0.5253837526709952 1.0936412587676703 0.15168713402422018 0.0626132747765875 358.5343952511944 3.5747108210820353 81.2506738852777 0.10756726307091843 3.000000113519323e-15 14.522878728846733 0.568257506096675 NMPGLSAATLASLGGT(ph)SSRR ddPTM_PC-9_AZD4547_30min_R2 2 NMPGLSAATLASLGGTSSRR 20 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3;C9JTC6;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 NMPGLSAATLAS(0.111)LGGT(0.296)S(0.296)S(0.296)RR;NMPGLSAATLAS(0.005)LGGT(0.408)S(0.179)S(0.408)RR 95.344 0.00045716 8474000.0 40850.6 36169.0 33803.5 61178.0 45508.0 47226.1 34506.6 46982.0 43069.9 40736.5 True False 53840.24105473505 47859.92192665516 33355.24350318546 47074.35729067782 39189.99972525941 44273.044501357515 37577.620551858236 39722.0114389569 45346.48698505647 39310.32753422559 1.3696207697038132 1.217489777590529 0.8485109536201314 1.1975061070069302 0.9969390280744567 1.1262446099644206 0.9559223468474343 1.0104726653415157 1.1535514921765915 1.0 15.262620763917775 -5.022194289907091 6.505544117224585 1.0402649526165757 1.3361187223205997 0.5517192626881666 0.09718076124532554 0.09744258142332679 17.46134489363066 0.023084832834445644 0.07050956377049011 9.501796176111157e-06 5.022194289907091 0.295853769704024 NMPGLSAATLASLGGT(ph)SSRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NMPGLSAATLASLGGTSSRR 20 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3;C9JTC6;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 NMPGLSAATLAS(0.021)LGGT(0.413)S(0.413)S(0.152)RR 70.615 0.0018997 5777400.0 20374.0 18483.0 17647.0 23188.0 21246.0 16613.0 19792.0 17730.0 16621.0 13015.0 True False 23822.915795157398 20317.870090108434 18067.771406620177 21888.851536510316 17082.998815687133 15741.785034484948 17917.158478328805 17264.60628648783 16864.050681157292 15374.516473316684 1.5495066681611336 1.321529046157075 1.1751765616809988 1.4237099146824954 1.1111242974916067 1.0238881373476478 1.1653802907834543 1.1229365369929845 1.0968833205535782 1.0 13.908253418130272 -1.522878745289567 0.310022810443806 1.0515712238217108 5.26844107876287 0.7095025516110203 0.09087201157765532 32.414248024949885 0.46279289267616497 0.09198162665374619 76.6615899447888 0.02999999999936246 1.522878745289567 4.21686985494116 NMPGLSAATLASLGGTS(ph)SR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NMPGLSAATLASLGGTSSR 19 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3;C9JTC6;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 NMPGLSAATLAS(0.002)LGGT(0.182)S(0.504)S(0.312)R;NMPGLSAATLASLGGT(0.162)S(0.538)S(0.3)R 127.37 3.2585999999999996e-05 49315800.0 56492.0 58356.0 53741.0 70353.0 71939.0 50668.0 56707.0 53226.0 47275.0 35800.0 True False 66054.97983214064 64149.19801863166 55022.38925387743 66411.34949750331 57843.069368432436 48010.88088408375 51335.30243687305 51828.873897608646 47966.307439486875 42290.25660735594 1.561943225964041 1.5168789022546054 1.301065391130941 1.570369981769081 1.3677634994149277 1.1352705028451582 1.2138801358784808 1.2255511802355334 1.1342165143340286 1.0 15.36803769387778 -6.620169364428309 3.7578295420075993 1.1603778679919787 1.4764629489196972 0.7611253693958984 0.09154738719857812 0.11958697087061186 3.243027723759822 0.03100218766008335 0.03105054483859856 2.3978976141191846e-07 6.620169364428309 0.3160850809277185 NMPGLSAATLASLGGTS(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 2 NMPGLSAATLASLGGTSSR 19 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3;C9JTC6;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 NMPGLSAAT(0.007)LAS(0.013)LGGT(0.138)S(0.421)S(0.421)R;NMPGLSAATLASLGGT(0.175)S(0.564)S(0.261)R 188.27 4.6456000000000005e-11 144295500.0 75024.0 59965.0 67238.0 58171.0 56181.0 53769.0 41697.0 45701.0 48385.0 35239.0 True False 73954.14400228327 59826.15472673865 61709.9511861858 62449.08939276736 52876.54403609574 51469.425211660906 43855.866635012084 47824.43529970301 42935.37178336211 41330.01419698404 1.7893568497172183 1.4475232077492082 1.493102588643411 1.5109864007093525 1.2793739625657878 1.2453280312547477 1.061114240754661 1.1571357094571935 1.0388424155560831 1.0 15.334902238832068 -5.852259548719972 0.37734474534468365 0.9791013084766609 1.887721250402975 0.8963989379184708 0.07765569379452121 0.8356280645819655 0.16931737746565945 0.07719560362153093 0.32151027664048687 1.4052074747565484e-06 5.852259548719972 0.9086199419263141 NMPGLSAATLASLGGTSS(ph)R ddPTM_PC-9_AZD4547_30min_R2 4 NMPGLSAATLASLGGTSSR 19 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3;C9JTC6;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 NMPGLSAATLASLGGT(0.112)S(0.337)S(0.551)R;NMPGLSAATLAS(0.003)LGGT(0.07)S(0.07)S(0.858)R;NMPGLSAATLASLGGT(0.064)S(0.214)S(0.722)R;NMPGLSAATLASLGGT(0.007)S(0.023)S(0.97)R 174.81 1.3472e-08 415396300.0 328678.0 298742.0 446456.0 622518.0 459842.0 491431.0 477092.0 523106.0 443041.0 478784.0 True False 433190.7670729001 395304.50928178284 440535.70173083124 479006.09290722496 396000.8757506973 460701.74188312335 519552.2637503291 442271.9874800354 466459.24277387245 462021.9178905072 0.93759787208961 0.8555968753314958 0.9534952448624572 1.0367605396173927 0.8571040905564657 0.9971426117327691 1.1245186508088039 0.9572532608395599 1.0096041436813759 1.0 18.817601767813855 -6.9850302273445015 24.82196814430513 1.0252173374710698 0.931088137599375 0.3492951424856404 0.061841114168096775 254.5140342003041 422017.96038572694 0.022081613713943165 0.0194678644472916 1.0350701222226097e-07 6.9850302273445015 -0.09412919987169477 NMPGLSAATLASLGGTSS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NMPGLSAATLASLGGTSSR 19 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3;C9JTC6;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 NMPGLSAATLASLGGT(0.004)S(0.232)S(0.764)R;NMPGLSAATLAS(0.001)LGGT(0.241)S(0.241)S(0.517)R;NMPGLSAAT(0.003)LAS(0.003)LGGT(0.17)S(0.224)S(0.6)R;NMPGLSAATLASLGGT(0.028)S(0.232)S(0.74)R 181.64 2.5165999999999998e-09 477018400.0 242413.0 265512.0 229090.0 306922.0 285531.0 215387.0 229850.0 228698.0 227630.0 158975.0 True False 283448.73302500654 291870.2766523225 234552.37442866326 289726.15539454966 229583.2502514339 204091.7265528566 208076.94403010645 222694.91982556134 230958.65811634852 187795.90905459237 1.509344556289604 1.5541886834578258 1.2489748877355937 1.5427713886479077 1.222514651182811 1.0867740813966666 1.1079950840122847 1.1858347764158368 1.2298386012722393 1.0 17.51880611010722 -6.4192397407433575 4.364955210411728 1.1342426023602172 1.4537019858427052 0.7286417016240687 0.09836305475273692 0.1280856863363471 4.099203721878925 0.031340028666017664 0.0353762604179915 3.8085552416914835e-07 6.4192397407433575 0.3194593834824879 NMPGLSAATLASLGGTSS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 5 NMPGLSAATLASLGGTSSR 19 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3;C9JTC6;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 NMPGLSAATLAS(0.001)LGGT(0.09)S(0.244)S(0.665)R;NMPGLSAATLAS(0.002)LGGT(0.278)S(0.189)S(0.531)R;NMPGLSAATLAS(0.011)LGGT(0.084)S(0.236)S(0.67)R;NMPGLSAATLASLGGT(0.017)S(0.295)S(0.688)R;NMPGLS(0.002)AAT(0.023)LAS(0.017)LGGT(0.245)S(0.245)S(0.468)R 119.72 0.00039533 329040600.0 496637.4 448303.6 477840.7 446189.2 412893.3 383660.3 340859.3 352152.0 319933.5 265574.6 True False 489555.25960385555 447265.58055789204 438554.4821644439 479003.4422115372 388607.7278734607 367252.0433248412 358507.326716636 368514.26751408115 283899.2201808881 311478.81575408863 1.5717128576421635 1.4359422148021987 1.4079753099828176 1.5378363406573006 1.2476216943763683 1.1790594568549577 1.1509846210526118 1.183111816519239 0.9114559508439427 1.0 18.248774520685124 -6.8090085326666125 0.5763623217470336 0.9809150007433194 1.5411709185054816 0.8605508081383284 0.07839588924012407 0.3185229220186839 0.22903294269882554 0.06698172964562173 0.0749574280966256 1.5523565102136943e-07 6.8090085326666125 0.5602559177621622 NMS(ph)EREVSTAPAGTDMPAAK ddPTM_PC-9_Lapatinib_30min_R1 1 NMSEREVSTAPAGTDMPAAK 20 1 A0A5F9ZI63 A0A5F9ZI63 1 NMS(0.969)EREVS(0.002)T(0.014)APAGT(0.015)DMPAAK 40.349000000000004 0.035601999999999995 10354000.0 32251.0 33224.0 27457.0 30734.0 36327.0 35077.0 24620.0 28105.0 34039.0 31877.0 True False 31791.09482589093 33147.07186927647 25199.591447085 32994.28088561848 34190.31728162994 33576.838478480735 25894.703133414805 29410.860902346834 30205.169373439374 37386.89697656742 0.850327184034992 0.886595961415351 0.6740220099806378 0.882509209210327 0.9144999999079634 0.8980910745153663 0.6926143977566405 0.7866622608658954 0.8079078986515179 1.0 15.19024511546093 NMSVIAHVDHGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NMSVIAHVDHGK 12 0 P13639 P13639 EEF2 Elongation factor 2 0 71.806 0.014790000000000001 10628000.0 62150.0 75863.0 100440.0 117250.0 133530.0 124630.0 127940.0 110200.0 108180.0 94024.0 False True 72670.76748154667 83394.17727889924 102834.87052082109 110680.86262962878 107365.75505312561 118094.18340142406 115820.59699461314 107307.36676655158 109761.92784354706 111069.80690642534 0.6542801280168851 0.7508267062097046 0.925858011146611 0.996498199757165 0.9666511362856665 1.0632428982335105 1.0427730111405549 0.9661254462876346 0.988224711113614 1.0 16.76110716383343 -5.182680013781507 1.5259093300962352 1.0076068760451768 0.6233188387566442 0.9469290291229356 0.028558317713448612 0.12329177050013787 0.4392776176556755 0.009107315645114349 0.056678088095227286 6.566288893240292e-06 5.182680013781507 -0.38428803728853267 NMTVEQLLTGS(ph)PTSPTVEPEKPTR ddPTM_PC-9_AZD4547_30min_R2 2 NMTVEQLLTGSPTSPTVEPEKPTR 24 1 Q9C0C9;K7ES11 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 1 NMT(0.004)VEQLLT(0.202)GS(0.792)PT(0.001)S(0.001)PTVEPEKPTR;NMTVEQLLT(0.015)GS(0.979)PT(0.004)S(0.001)PTVEPEKPTR 66.501 0.0033849000000000006 0.0 14940.900000000001 10132.599999999999 17099.0 24762.0 20274.8 20909.5 15890.5 22248.5 17527.3 16685.0 True False 19691.79540997418 13407.764796207412 16872.256087711863 19053.503469086347 17459.993988522674 19602.025659563988 17304.723716022523 18810.50554466886 18453.757295307856 16100.863228518756 1.223027307945512 0.832735773598699 1.0479100311731593 1.1833839713225878 1.0844135336543044 1.2174518459882187 1.0747699344077044 1.1682917417341099 1.14613465336576 1.0 13.974850418331448 -5.565277715323753 8.024853726109129 1.1310687644382953 1.0062918550600646 0.12695915925442758 0.10556723501344879 0.33124663944387506 54.85851267286832 0.02652588014185595 0.046309519069937854 2.7209607974388e-06 5.565277715323753 -0.12477690937823072 NMTVEQLLTGS(ph)PTSPTVEPEKPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NMTVEQLLTGSPTSPTVEPEKPTR 24 1 Q9C0C9;K7ES11 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 1 NMTVEQLLT(0.023)GS(0.974)PT(0.003)SPTVEPEKPTR 107.3 1.7969e-06 9402000.0 50216.0 48044.0 48697.0 59071.0 62124.0 59073.0 58785.0 60515.0 54751.0 41998.0 True False 58716.5769887908 52813.49080826544 49858.12116440094 55761.44338076596 49951.24816086543 55975.10788792684 53216.45923345588 58926.54537094254 55551.6297962844 49611.904944014954 1.1835178886005306 1.0645326130464723 1.004962845523949 1.1239528787231716 1.0068399553944443 1.1282595971892735 1.072655026923649 1.187750106298857 1.1197237811967145 1.0 15.598398732880034 NMTVEQLLTGS(ph)PTSPTVEPEKPTR ddPTM_PC-9_Lapatinib_30min_R1 1 NMTVEQLLTGSPTSPTVEPEKPTR 24 1 Q9C0C9;K7ES11 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 1 NMT(0.001)VEQLLT(0.128)GS(0.863)PT(0.007)S(0.001)PTVEPEKPTR 78.757 0.0002695 4882700.0 21733.0 18160.0 21294.0 17893.0 21021.0 20994.0 18580.0 14718.0 17239.0 15628.0 True False 21423.083434655924 18117.95163574708 19543.289517217047 19208.910909298225 19784.58610887612 20096.135559404294 19541.981487361783 15401.852010700619 15297.362285282205 18329.278976998954 1.1687902978365556 0.9884705044035248 1.0662334040385075 1.047990536529184 1.079397947606308 1.0963953129101551 1.0661620411738304 0.8402868454360968 0.8345861451767175 1.0 14.161862414921666 -7.753783286699281 24.982824239512748 0.8780773640821415 1.0699541754596738 0.6568997449419804 0.05990981430881262 89.16822975754839 290970.0407166969 0.02729535679573756 0.015374490460875552 1.7628554933001235e-08 7.753783286699281 0.1918768113775322 NMTVEQLLTGSPT(ph)SPTVEPEKPTR ddPTM_PC-9_AZD4547_30min_R2 4 NMTVEQLLTGSPTSPTVEPEKPTR 24 1 Q9C0C9;K7ES11 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 1 NMTVEQLLT(0.004)GS(0.007)PT(0.462)S(0.462)PT(0.065)VEPEKPTR;NMTVEQLLT(0.002)GS(0.001)PT(0.487)S(0.487)PT(0.023)VEPEKPTR;NMTVEQLLTGSPT(0.453)S(0.453)PT(0.092)VEPEKPTR;NMTVEQLLTGS(0.006)PT(0.494)S(0.494)PT(0.006)VEPEKPTR 111.53 2.9919e-07 78047700.0 123607.0 120312.0 149274.0 231388.0 184254.0 176732.0 148292.0 170537.0 157664.0 169306.0 True False 162911.45481468187 159200.5011706083 147294.52922610124 178045.07150896362 158673.51255554942 165680.92010167893 161489.70072033053 144184.42520040445 165997.79716256453 163378.64847273592 0.9971404240246728 0.9744266013877275 0.901553113598447 1.089769521129777 0.9712010353790405 1.0140916310084864 0.988438221456333 0.8825169417683454 1.0160311565453162 1.0 17.317859928206566 -10.03186344154113 11.662890124999869 0.999999965710501 0.980220676609057 0.009139882001382604 0.055347915737077015 0.0 0.0 0.05262410110725409 0.012763219254023055 9.292585345506004e-11 10.03186344154113 -0.019779289101443998 NMTVEQLLTGSPT(ph)SPTVEPEKPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NMTVEQLLTGSPTSPTVEPEKPTR 24 1 Q9C0C9;K7ES11 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 1 NMTVEQLLTGSPT(0.49)S(0.49)PT(0.019)VEPEKPTR;NMTVEQLLTGS(0.006)PT(0.489)S(0.489)PT(0.015)VEPEKPTR;NMTVEQLLT(0.02)GS(0.002)PT(0.481)S(0.481)PT(0.017)VEPEKPTR;NMTVEQLLT(0.005)GS(0.013)PT(0.455)S(0.455)PT(0.069)VEPEKPT(0.004)R 123.18 2.5511999999999996e-09 97456000.0 164206.0 180712.0 145373.0 214108.0 245635.0 259954.0 261482.0 282069.0 236521.0 229192.0 True False 192002.83258366614 198651.89307599832 148839.24365017255 202112.22290750185 197504.5850556018 246321.55461713695 236712.53199425875 274664.98762680957 239979.67217122996 270742.69531712664 0.7091708692593504 0.7337294653261583 0.5497442635556021 0.7465103450741802 0.7294918329163435 0.9097994475109118 0.8743081017088655 1.0144871583888484 0.8863754270087941 1.0 18.04656288864375 -6.747321244925128 1.4700186344309458 0.9524545133488387 0.6734072334342397 0.7857068409919139 0.06410796281134588 0.17525218727075495 0.7890861694050589 0.02810509401385983 0.025760832264767247 1.7892818437715998e-07 6.747321244925128 -0.279047279914599 NMTVEQLLTGSPT(ph)SPTVEPEKPTR ddPTM_PC-9_Lapatinib_30min_R1 5 NMTVEQLLTGSPTSPTVEPEKPTR 24 1 Q9C0C9;K7ES11 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 1 NMTVEQLLTGSPT(0.617)S(0.378)PT(0.004)VEPEKPTR;NMTVEQLLT(0.001)GS(0.001)PT(0.493)S(0.493)PT(0.011)VEPEKPTR;NMTVEQLLT(0.005)GS(0.021)PT(0.455)S(0.455)PT(0.063)VEPEKPTR;NMTVEQLLTGSPT(0.496)S(0.496)PT(0.008)VEPEKPTR;NMTVEQLLT(0.002)GS(0.002)PT(0.422)S(0.422)PT(0.146)VEPEKPT(0.005)R 121.59 4.7127e-09 51769000.0 175409.0 149007.7 146478.0 132808.0 184956.0 189406.0 189738.0 175747.0 192975.0 185228.0 True False 172907.63549392886 148662.68182565554 134435.1442614313 142575.1433545002 174077.25171748677 181305.54690695117 199561.7052448359 183912.84721596682 171240.12338316234 217244.41299920436 0.7959129217954255 0.6843107252944637 0.6188198002676536 0.6562891141187708 0.8012967943075447 0.8345694345088414 0.9186045454046581 0.8465711254753436 0.7882371795853249 1.0 17.72895954932695 -6.510251712364298 2.5532629378167186 0.8716221081794248 0.683980152709095 0.6324121906336485 0.06755281192590938 0.19354121043389824 2.533075968253069 0.02391540639356486 0.02580938455475237 3.0885048497997257e-07 6.510251712364298 -0.1876419554703298 NMTVEQLLTGSPTS(ph)PTVEPEKPTR ddPTM_PC-9_AZD4547_30min_R2 2 NMTVEQLLTGSPTSPTVEPEKPTR 24 1 Q9C0C9;K7ES11 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 1 NMTVEQLLTGSPT(0.263)S(0.733)PT(0.004)VEPEKPTR;NMTVEQLLTGSPT(0.239)S(0.76)PT(0.001)VEPEKPTR 154.46 1.7913e-07 38954000.0 46885.0 37385.0 57034.0 78739.0 66009.0 59222.0 52336.0 60826.0 57498.0 59345.0 True False 61793.45473141774 49468.97014647913 56277.69189464638 60586.940055423176 56844.78974827826 55518.838978009924 56993.80261173374 51426.739342428824 60537.22689550652 57267.34961321216 1.0790346532321684 0.8638250325987871 0.9827186394123353 1.057966545765288 0.992621277782403 0.9694675823656621 0.9952233340057473 0.8980115142357514 1.0570984567014077 1.0 15.805425215274441 -5.5078691642202635 24.900055918350937 0.9925836564643963 0.9593903523128207 0.014586073231537156 0.06436208912845365 2285.4432542220034 3791417.8163907966 0.01633282389668484 0.03218792022058272 3.105495010247788e-06 5.5078691642202635 -0.03319330415157562 NMTVEQLLTGSPTS(ph)PTVEPEKPTR ddPTM_PC-9_Lapatinib_30min_R1 2 NMTVEQLLTGSPTSPTVEPEKPTR 24 1 Q9C0C9;K7ES11 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 1 NMTVEQLLT(0.002)GS(0.002)PT(0.11)S(0.729)PT(0.139)VEPEKPT(0.019)R;NMTVEQLLT(0.004)GS(0.015)PT(0.29)S(0.674)PT(0.015)VEPEKPT(0.001)R 50.224 0.016016 37667000.0 57716.0 42799.0 61855.0 46151.0 37472.0 39682.0 34128.7 34352.0 45385.0 30638.8 True False 56892.95925618186 42699.90154506272 56769.52066720483 49545.09849522286 35267.97063278655 37984.89336326003 35895.71709298839 35948.11932814155 40273.263374762624 35934.675756365235 1.5832328540241303 1.1882645563456666 1.5797977711583788 1.3787545720778283 0.9814467472004227 1.0570540171503184 0.9989158476441812 1.000374111397789 1.1207354046496127 1.0 15.133089048027095 -6.213255072317161 5.39934387395423 1.0263584825839072 1.430187719455338 0.768184099345987 0.10944694228251262 0.0953251110881561 6.65512356332837 0.030864092326791628 0.039606985807942065 6.119908481879607e-07 6.213255072317161 0.4038292368714309 NNASTDYDLSDK ddPTM_PC-9_Lapatinib_30min_R1 2 NNASTDYDLSDK 12 0 P39023;G5E9G0;B5MCW2 P39023 RPL3 60S ribosomal protein L3 0 ; 174.05 0.0052357 30638000.0 104908.0 111419.0 117665.0 113454.0 100490.0 89753.0 101569.0 93422.0 103653.0 105479.0 False True 103411.99268222907 111161.01615106275 107991.03790003476 121797.78563144947 94579.37577094151 85914.47341446186 106827.74583906616 97762.72717377836 91978.50762552109 123710.9046080672 0.8359165508477381 0.898554711108417 0.8729306300213785 0.9845355671540941 0.7645193127524345 0.6944777720820203 0.8635273194186951 0.7902514938638905 0.7434955545505174 1.0 16.916613147997694 -6.283851739278025 24.95044718885993 0.7958535442109906 0.8962355648995916 0.197020880108701 0.08501230448267454 1092.519096433807 1216238.1106763722 0.025311499864989248 0.028721131330129827 5.201735445937291e-07 6.283851739278025 0.10038202068860091 NNAYLAQS(ph)PQLYK ddPTM_PC-9_AZD4547_30min_R2 3 NNAYLAQSPQLYK 13 0 P14868;P14868-2 P14868 DARS Aspartate--tRNA ligase, cytoplasmic 1 NNAYLAQS(0.997)PQLY(0.003)K;NNAYLAQS(0.999)PQLYK;NNAYLAQS(1)PQLYK 117.48 0.00025804 19963000.0 47274.8 50734.7 54227.5 94894.0 70464.0 71284.0 63673.0 76940.0 57561.0 69219.0 True False 62307.20302307405 67133.69960386712 53508.407918380966 73017.65439768523 60681.289897175804 66826.60021121317 69339.77364905464 65050.69090531152 60603.5569468895 66795.66387862385 0.9328031103380319 1.0050607435515204 0.8010760700816223 1.0931496171722692 0.9084615134216102 1.0004631488152516 1.0380879479700023 0.9738759543361504 0.9072977709603098 1.0 16.02746683099354 -5.769550587629265 24.999744610239294 0.9868706572264383 0.922188043441114 0.19519526193380976 0.06969431303353239 327.3244694792048 1008856.6754264291 0.018961457118324716 0.028684518665876155 1.7000019219393533e-06 5.769550587629265 -0.06468261378532425 NNCPFS(ph)ADENYRPLAK ddPTM_PC-9_AZD4547_30min_R2 2 NNCPFSADENYRPLAK 16 1 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 NNCPFS(0.996)ADENY(0.004)RPLAK;NNCPFS(0.989)ADENY(0.011)RPLAK 64.346 0.014325 13386900.0 31403.0 33920.0 42811.0 61096.0 53287.0 46805.0 46795.0 51089.0 51063.0 44769.0 True False 41388.50077702275 44883.97665824721 42243.29816778954 47011.26112379049 45889.01985057351 43878.27595092626 50959.664346073056 43194.36895842808 53762.0859328194 43201.65093662304 0.9580305354010619 1.0389412368544004 0.9778167558864959 1.088182051022915 1.0622052365057264 1.0156620175302058 1.179576781008463 0.9998314421315602 1.2444451720534604 1.0 15.398798825099501 -5.639215217471854 0.6117867335389218 1.0999187944758408 0.9576810162231842 0.22258382086816408 0.07675175159969673 2.2868018304485793 1.2839497585080182 0.04257454136939791 0.20171759163876385 2.2950110585206315e-06 5.639215217471854 -0.1422377782526566 NNCPFS(ph)ADENYRPLAK ddPTM_PC-9_Lapatinib_30min_R1 1 NNCPFSADENYRPLAK 16 1 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 NNCPFS(1)ADENYRPLAK 93.115 0.0013494000000000002 8259500.0 27392.0 36364.0 31222.0 29462.0 32295.0 23697.0 28445.0 30987.0 30423.0 24991.0 True False 27001.385056922405 36279.8013921975 28655.047680405285 31628.73376235089 30395.47159441294 22683.534550405027 29917.742917546086 32426.769143605106 26996.44137160745 29310.66105158569 0.9212137866628446 1.237768105207398 0.9776322557165618 1.079086333354457 1.0370107839232292 0.7739004763653348 1.0207119813808345 1.106313129087576 0.9210451215717961 1.0 14.839137885451004 -6.5414093090842345 24.98194852745443 0.9668804912494993 1.061162507254444 0.13301971582640126 0.10993275536952439 484.4728737809119 653136.8281224823 0.03592639550906559 0.035932640960633346 2.874687833461304e-07 6.5414093090842345 0.09428201600494468 NNES(ph)QWKDSPLATR ddPTM_PC-9_AZD4547_30min_R2 1 NNESQWKDSPLATR 14 1 O95155-2;O95155;O95155-4;O95155-3;K7EP75 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 NNES(0.985)QWKDS(0.014)PLATR 64.53399999999999 0.019353 22809000.0 39350.0 34378.0 35494.0 31563.0 37494.0 39744.0 49797.0 46250.0 41929.0 42634.0 True False 51862.48146915402 45490.01620156904 35023.32636863238 24286.637993488923 32288.605293550052 37258.801397150164 54228.83653042849 39103.12521927029 44145.281340249996 41141.396636779646 1.26059117358184 1.1056993665815857 0.8512916242936238 0.5903211844727974 0.7848203496495945 0.9056280156479055 1.3181087897718309 0.9504569221238547 1.0730136784122912 1.0 15.328303149755394 -7.062810221914159 24.997076119899184 1.0856381942654922 0.9007955039470421 0.15583757391872155 0.19066817336399808 441.5128962417228 175710.55507544873 0.0800867739880791 0.06203500570459812 8.653459752179973e-08 7.062810221914159 -0.18484269031845013 NNESQWKDS(ph)PLATR ddPTM_PC-9_Lapatinib_30min_R1 1 NNESQWKDSPLATR 14 1 O95155-2;O95155;O95155-4;O95155-3;K7EP75 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 NNES(0.005)QWKDS(0.995)PLATR 57.266999999999996 0.031977 17850000.0 34608.0 74513.0 75934.0 57723.0 85891.0 78618.0 73921.0 63274.0 77103.0 45514.0 True False 34114.48357367008 74340.46972656515 69690.99963371645 61968.1419782832 80839.0602482032 75255.69140750918 77748.26768176924 66213.94103309355 68418.84820941559 53381.03425640715 0.6390749832572873 1.3926382424417396 1.3055385794693866 1.1608643939086918 1.5143779316808639 1.4097833145388428 1.4564773568889287 1.2404019883737287 1.2817070549959138 1.0 15.704039637485954 -4.757952603696262 24.98782374243903 1.3241503431666788 0.6390740174452832 0.6586398594367597 0.14374213706823036 57.42726764390616 411485.8854533203 0.03458361433075508 0.2466082500183385 1.7460126919114875e-05 4.757952603696262 -0.6850763257213955 NNFEGEVTK ddPTM_PC-9_Lapatinib_30min_R1 1 NNFEGEVTK 9 0 P07237;H7BZ94;I3L398;I3L312;I3NI03;I3L4M2 P07237 P4HB Protein disulfide-isomerase 0 103.26 0.013429 8462400.0 60694.0 65989.0 54799.0 57170.0 65494.0 47256.0 59536.0 54504.0 52434.0 50109.0 False True 59828.49243008356 65836.20652485211 50293.63775025718 61374.472513529276 61641.7716861582 45234.9710391164 62618.48276811475 57036.45481663448 46528.33076550192 58770.27388395447 1.0180060169230896 1.1202297041332454 0.8557666048922125 1.0443114938466505 1.0488596974700795 0.7696913430833356 1.0654788318965267 0.9704983667296919 0.7916983823722684 1.0 15.842799001206073 -4.8716752626605375 0.5199252942289248 0.9315303800575901 1.1373553948685236 0.11398486665388852 0.10796957342334816 8.991563059772675 1.9937722384798675 0.06610642938687748 1.1193129319085051 1.3437693694444311e-05 4.8716752626605375 0.2058250148109334 NNMTAS(ph)MFDLSMK ddPTM_PC-9_AZD4547_30min_R2 1 NNMTASMFDLSMK 13 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3;Q7L804;Q7L804-2 Q6WKZ4;Q7L804 RAB11FIP1;RAB11FIP2 Rab11 family-interacting protein 1;Rab11 family-interacting protein 2 1 NNMT(0.026)AS(0.959)MFDLS(0.015)MK 88.561 0.0057604 4398900.0 18053.0 27945.0 27927.0 22816.0 22726.0 29681.0 33689.0 25749.0 29469.0 23797.0 True False 23793.478474272877 36977.674755740496 27556.669732822356 17556.123703686066 19570.88717931452 27825.04237793913 36687.25573575929 21770.08370315656 31026.671177844142 22963.87427324308 1.0361264911642731 1.6102541895043354 1.200000897275887 0.7645105305310791 0.8522467483685023 1.2116876293108851 1.597607411503134 0.9480144092463747 1.3511078665848484 1.0 14.487078441566112 -14.522397578040234 0.011004272460379504 6.3352909140997585e-06 2.1207236270806247 0.009360873230071842 0.2765361611774221 102117.63923772807 85.02993300843043 9669.863262406157 6928.742073838215 3.0033256274814695e-15 14.522397578040234 2.1207172917897106 NNMTAS(ph)MFDLSMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NNMTASMFDLSMK 13 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3;Q7L804;Q7L804-2 Q6WKZ4;Q7L804 RAB11FIP1;RAB11FIP2 Rab11 family-interacting protein 1;Rab11 family-interacting protein 2 1 NNMT(0.005)AS(0.994)MFDLS(0.001)MK 89.911 0.0036692 11132000.0 61224.0 83601.0 59904.0 66743.0 72472.0 51769.0 68356.0 49299.0 53238.0 49578.0 True False 71588.01397088039 91900.35478023885 61332.33854718512 63003.60609372558 58271.631844604985 49054.14250588402 61880.82482541643 48004.953486608196 54016.505033599205 58566.09894076793 1.2223456106113957 1.5691732323367522 1.0472327789702176 1.0757692117661042 0.9949720554810939 0.8375859651416422 1.0565980310213408 0.8196713517688625 0.9223169377941657 1.0 15.837778179985532 -5.414903155428311 4.60204302109073 0.9577087709342441 1.3928771032714122 0.7052754118457389 0.11122563398031315 0.11093803923324527 3.732547561934253 0.029074529439271718 0.06282390877742725 3.846775528322797e-06 5.414903155428311 0.4351683323371681 NNMTASMFDLS(ph)MK ddPTM_PC-9_AZD4547_30min_R2 1 NNMTASMFDLSMK 13 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3;Q7L804;Q7L804-2 Q6WKZ4;Q7L804 RAB11FIP1;RAB11FIP2 Rab11 family-interacting protein 1;Rab11 family-interacting protein 2 1 NNMT(0.019)AS(0.485)MFDLS(0.496)MK 69.345 0.02706 3116200.0 24066.0 20653.0 25664.0 26309.0 20425.0 23022.0 27043.0 26389.0 23656.0 22510.0 True False 31718.487396103217 27328.678358572517 25323.67859144028 20243.866519998097 17589.34131116339 21582.43070061369 29449.774610767276 22311.186408893467 24906.40786531884 21721.93175151075 1.4602056464843285 1.258114548521764 1.165811534679876 0.9319551663995144 0.8097503257250617 0.9935778708591442 1.3557622290530886 1.0271271756178746 1.146601883766006 1.0 14.406864788603283 -5.062870972840391 1.7920684348100813 1.0440235621870892 1.4788791335703355 0.48215559224021387 0.1372121709840159 0.4982082582513427 2.414031056862311 0.042458975143252455 0.30560294438913727 8.652249354742935e-06 5.062870972840391 0.43485557138324626 NNMTASMFDLS(ph)MKDK ddPTM_PC-9_Lapatinib_30min_R1 1 NNMTASMFDLSMKDK 15 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3;Q7L804;Q7L804-2 Q6WKZ4;Q7L804 RAB11FIP1;RAB11FIP2 Rab11 family-interacting protein 1;Rab11 family-interacting protein 2 1 NNMT(0.022)AS(0.022)MFDLS(0.956)MKDK 56.817 0.030685000000000004 4199800.0 28666.0 22285.0 26947.0 21323.0 16140.0 19062.0 15107.0 17410.0 21660.0 12181.0 True False 28257.217583299407 22233.400451686306 24731.521678428096 22891.164551442802 15190.676932460898 18246.76269569232 15889.166540881299 18218.932158329782 19220.42271008833 14286.469619837748 1.9779006525210618 1.556255747103098 1.731114987574444 1.6022967997395832 1.0632911654652313 1.2772058584967299 1.1121828529854636 1.2752578238805434 1.3453584560456733 1.0 13.802361830538272 -6.12386303633857 4.238563810287494 1.1953257157054886 1.7269352425675608 0.7850164647485544 0.13897778240856654 0.10738191545890613 3.1938284633048655 0.04038995010106349 0.05349225750491687 7.51859971076485e-07 6.12386303633857 0.5316095268620722 NNPATPS(ph)TAMGSSVPYSTAK ddPTM_PC-9_AZD4547_30min_R2 2 NNPATPSTAMGSSVPYSTAK 20 0 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;A0A494C104 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 NNPAT(0.06)PS(0.735)T(0.188)AMGS(0.013)S(0.003)VPY(0.001)STAK;NNPAT(0.276)PS(0.674)T(0.039)AMGS(0.01)S(0.001)VPYSTAK 119.72 0.00017251 2480100.0 24805.3 27022.0 28473.8 36526.0 33179.0 37970.0 37441.0 47285.0 39706.0 42063.0 True False 32692.869417707912 35756.333055989235 28096.218807549583 28105.495021074534 28572.6685612284 35595.72989758933 40773.1764671722 39978.18975120421 41804.77809859443 40590.38717298074 0.8054337909708369 0.880906429978344 0.6921889827710738 0.6924175150461028 0.7039269775738426 0.8769497503409837 1.0045032655986372 0.984917674739894 1.0299181902463361 1.0 15.308850480853232 -7.039135105361985 3.143697799752359 1.0030202678041382 0.7555670299041387 0.8170823651004329 0.05555945660091037 0.11991100240902315 2.3860116972592937 0.025191085227915296 0.01990931021709252 9.138289127546747e-08 7.039135105361985 -0.2474532378999995 NNPS(ph)PPPDSDLER ddPTM_PC-9_AZD4547_30min_R2 3 NNPSPPPDSDLER 13 0 E7ESD5;E9PLN6;F2Z2Y1;O95677-3;O95677-5;O95677-2;O95677-4;O95677 E7ESD5 EYA4 Eyes absent homolog;Eyes absent homolog 4 1 NNPS(0.999)PPPDS(0.001)DLER;NNPS(0.957)PPPDS(0.043)DLER;NNPS(0.999)PPPDS(0.001)DLER 100.11 0.0079193 8698500.0 53424.0 63852.0 57373.0 84572.0 76054.0 73140.0 54218.0 65808.0 57854.0 59226.0 True False 70411.72071176842 84490.91030608496 56612.19653314772 65075.23202437495 65495.2148875996 68566.54423781102 59043.29696581666 55638.88571739976 60912.044328718126 57152.5157669914 1.2319968730481488 1.4783410523965583 0.9905460113768826 1.1386241034372688 1.1459725614638043 1.1997117417779852 1.0330830790814862 0.9735159506230199 1.0657806311983566 1.0 15.802529384632757 -1.522878745280338 0.24395257297127942 0.9898378726880167 3.164874572654852 0.42353773065800226 0.11031523045308812 46.51636079748022 0.6260223566144344 0.14751464208802434 41.180610407919154 0.029999999999999964 1.522878745280338 2.1750366999668356 NNPS(ph)PPPDSDLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NNPSPPPDSDLER 13 0 E7ESD5;E9PLN6;F2Z2Y1;O95677-3;O95677-5;O95677-2;O95677-4;O95677 E7ESD5 EYA4 Eyes absent homolog;Eyes absent homolog 4 1 NNPS(0.999)PPPDS(0.001)DLER;NNPS(1)PPPDSDLER 164.7 2.864e-13 4006600.0 31966.0 41750.0 43776.0 36923.0 38774.0 35621.0 41220.0 37814.0 25215.1 30449.0 True False 37377.21244272117 45894.66408386232 44819.78586140449 34854.32401598114 31176.513041487942 33752.97205281336 37315.34319304332 36821.42256724481 25583.823135217444 35969.162665848606 1.0391460259988052 1.2759447449533656 1.2460614187151824 0.9690057102461836 0.8667567085482614 0.9383863718590415 1.0374259623361448 1.0236941824115742 0.711271023262055 1.0 15.13447295459437 -5.81916515500339 6.112102440221386 0.9359029914414251 1.1956344379835946 0.5448414665441585 0.10557890005469903 0.14349515750579525 10.841752591752266 0.02973540712045868 0.04508099088903884 1.516473567994134e-06 5.81916515500339 0.2597314465421695 NNPS(ph)PPPDSDLER ddPTM_PC-9_Lapatinib_30min_R1 1 NNPSPPPDSDLER 13 0 E7ESD5;E9PLN6;F2Z2Y1;O95677-3;O95677-5;O95677-2;O95677-4;O95677 E7ESD5 EYA4 Eyes absent homolog;Eyes absent homolog 4 1 NNPS(0.986)PPPDS(0.014)DLER 165.89 0.00030641 10224000.0 20639.0 27586.0 22423.0 24704.0 25535.0 22240.0 20417.0 25342.0 25063.0 24645.0 True False 20344.684075270936 27522.12631187878 20579.467495283083 26520.814570128154 24033.08150374158 21288.84704397216 21474.09235885176 26519.48183551942 22240.141014909674 28904.8554126017 0.7038500551156962 0.952162739408823 0.7119726842262984 0.9175210943475548 0.8314548251732072 0.7365145661545439 0.7429233619168931 0.9174749867095918 0.7694257832271875 1.0 14.819024235296586 -10.80126474133929 3.226895614467267 1.000843189278284 0.8135271928509452 0.2990576098284877 0.08738664919821272 35082644.4816743 49297772.04268741 299694.38758363586 0.02125339683488882 1.580284420865518e-11 10.80126474133929 -0.18731599642733887 NNPSPPPDS(ph)DLER ddPTM_PC-9_Lapatinib_30min_R1 1 NNPSPPPDSDLER 13 0 E7ESD5;E9PLN6;F2Z2Y1;O95677-3;O95677-5;O95677-2;O95677-4;O95677 E7ESD5 EYA4 Eyes absent homolog;Eyes absent homolog 4 1 NNPS(0.298)PPPDS(0.702)DLER 64.65 0.041565 6649500.0 16094.0 21362.0 17754.0 12420.0 16536.0 16635.0 18936.0 22631.0 16938.0 17381.0 True False 15864.49660872186 21312.537601477372 16294.334652421874 13333.408231905434 15563.38499102685 15923.559828078996 19916.4134254404 23682.51887852734 15030.264074952718 20385.28269127327 0.7782328481278941 1.0454864876905068 0.7993185524671341 0.65407031307019 0.7634618183484585 0.7811301942305519 0.9769996191402542 1.1617459143044202 0.737309572919831 1.0 14.315240342972437 -7.268443189581298 21.368590117257654 0.9824927254410026 0.8057926195015691 0.2691177950348591 0.13276203033312786 103.97214118083022 317210.4866389134 0.05585645555064999 0.038764680416718836 5.389603426083909e-08 7.268443189581298 -0.17670010593943353 NNQITNNQR ddPTM_PC-9_AZD4547_30min_R2 2 NNQITNNQR 9 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 ; 123.21 0.0069566 9973000.0 5553.9 4919.4 5341.1 10151.8 8412.1 5568.2 8287.2 4849.8 5780.1 6780.799999999999 False True 7319.92467170355 6509.499845889772 5270.273524187259 7811.459353746497 7244.225118415544 5220.019573762365 9024.744745566339 4100.374847317125 6085.624285691975 6543.406255914892 1.11867189433435 0.9948182324772405 0.8054327238849355 1.1937909780071123 1.1071030645341864 0.797752633659838 1.3792120483744148 0.6266422543473598 0.9300391948292823 1.0 12.675826129746573 -7.786941448555092 24.999845839747422 0.8337558407460118 1.0418942272220513 0.19831373928781748 0.18561851516365271 364.7362661104141 357548.1001651696 0.09652806940339385 0.046397146230991816 1.6332721302843874e-08 7.786941448555092 0.20813838647603944 NNQITNNQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NNQITNNQR 9 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 101.46 0.016086000000000003 2510100.0 3076.5 1232.2 2414.0 3324.8 3806.2 3175.0 4034.0 2940.8 2664.5 2330.4 False True 3597.290686355244 1354.5246726738962 2471.558915145982 3138.5222351470375 3060.402433035318 3008.4974107319385 3651.87031636916 2863.60711603516 2703.4632717612435 2752.88307256375 1.3067357354212288 0.49203857809058066 0.8978074440496407 1.1400855584556824 1.1117081083233864 1.0928533219284668 1.3265620878580167 1.0402211211129622 0.9820479840589517 1.0 11.426727618091784 -5.704223856080642 5.7156960050368 1.1104816909494748 0.8529546446664028 0.15718770959623884 0.20459242323335206 0.27937556117744583 18.578322551264346 0.053705927541210306 0.09304110737957692 1.9759508782905405e-06 5.704223856080642 -0.257527046283072 NNQITNNQR ddPTM_PC-9_Lapatinib_30min_R1 1 NNQITNNQR 9 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 117.81 0.0084574 13477000.0 4559.9 2427.1 2897.7 2213.7 3952.6 3701.9 3220.3 2656.8 3043.4 3275.1 False True 4494.874989816755 2421.4801990705787 2659.4622914454694 2376.502882686719 3720.1158391105923 3543.578366550385 3387.0313769510863 2780.244627125247 2700.6202435772293 3841.196671203562 1.1701756964212864 0.630397349144806 0.6923525450760584 0.6186881553091864 0.9684783564974216 0.9225193786914524 0.8817646340117826 0.7237964793544698 0.7030674226662401 1.0 11.90734011713461 -4.746128983608957 24.993029541176767 0.7884622749977694 1.1701767301697577 0.41688096262065133 0.13354755298721438 902.9805971979495 1473964.3052794642 0.034888843451059415 0.8243991216508099 1.7942006777452143e-05 4.746128983608957 0.3817144551719882 NNQVLGIGSGS(ph)TIVHAVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NNQVLGIGSGSTIVHAVQR 19 0 P49247 P49247 RPIA Ribose-5-phosphate isomerase 1 NNQVLGIGS(0.045)GS(0.478)T(0.478)IVHAVQR 131.41 2.2817e-05 9023300.0 21974.0 22335.0 22026.0 28595.0 36392.0 31644.0 26815.0 30103.0 26768.0 22542.0 True False 25693.764193716914 24552.271193127308 22551.18337407016 26992.914856240837 29261.24884215788 29984.532933921724 24274.889076211937 29312.82814676496 27159.431359919294 26628.68615762618 0.9648904208651122 0.9220233791405361 0.8468755552031519 1.0136780574324484 1.0988619066276297 1.1260237458367606 0.9116067136215003 1.1007988893349916 1.0199313326670123 1.0 14.700693628201725 -5.919934552352181 6.493352858162344 1.0464484874376803 0.9132596680325815 0.4627632208192273 0.06346461252183096 0.1839416781640224 12.002315576044596 0.017952433755269847 0.02681044146761004 1.2024456280513012e-06 5.919934552352181 -0.13318881940509875 NNQVLGIGSGS(ph)TIVHAVQR ddPTM_PC-9_Lapatinib_30min_R1 1 NNQVLGIGSGSTIVHAVQR 19 0 P49247 P49247 RPIA Ribose-5-phosphate isomerase 1 NNQVLGIGS(0.063)GS(0.724)T(0.213)IVHAVQR 112.88 5.6341e-05 8191900.0 31859.0 32142.0 36023.0 27110.0 34665.0 38337.0 31204.0 26880.0 45619.0 25219.0 True False 31404.684817774938 32067.5771737986 33061.32799280123 29103.75983630887 32626.0728540122 36697.415877911895 32819.59043765539 28128.942930264475 40480.90783063339 29578.070547794767 1.0617556938688266 1.0841673097635316 1.1177648636471373 0.9839641091287727 1.1030493960480692 1.240696745875059 1.109591999404515 0.95100668871593 1.3686121873710757 1.0 14.852240324416547 -6.519123293072546 24.979306311445693 1.1341148668259793 1.0644938466524483 0.08243639642766853 0.11321786352617275 442.02321089793145 2940127.6871626414 0.035614907638677466 0.03637879960182187 3.026054231166024e-07 6.519123293072546 -0.069621020173531 NNQVLGIGSGST(ph)IVHAVQR ddPTM_PC-9_Lapatinib_30min_R1 1 NNQVLGIGSGSTIVHAVQR 19 0 P49247 P49247 RPIA Ribose-5-phosphate isomerase 1 NNQVLGIGS(0.004)GS(0.237)T(0.759)IVHAVQR 122.47 6.7684e-05 6848200.0 37992.0 26084.0 31063.0 33260.0 30418.0 30406.0 24654.0 24790.0 35861.0 26019.0 True False 37450.22711312046 26023.604100596196 28509.120046647553 35706.051352107446 28628.873044088952 29105.6062598479 25930.463487051526 25941.83390034435 31821.956546928788 30516.349481861784 1.2272184500764096 0.8527757920738203 0.9342244577318372 1.1700629976508266 0.9381486819419634 0.9537709049094356 0.8497236375689038 0.8500962382726538 1.0427838547937403 1.0 14.897294769657355 -6.486980249252179 24.939272732663532 0.926714568067519 1.0280035758829829 0.16254393777066078 0.11434141668360642 1125.9587208987175 782222.6028598924 0.03536459531093808 0.040083916949019506 3.2585151966795846e-07 6.486980249252179 0.1012890078154639 NNRPAFFSPS(ph)LK ddPTM_PC-9_AZD4547_30min_R2 1 NNRPAFFSPSLK 12 1 Q6ICG6-2;B0QY16;Q6ICG6-3;Q6ICG6 Q6ICG6-2 KIAA0930 Uncharacterized protein KIAA0930 1 NNRPAFFS(0.008)PS(0.992)LK 80.737 0.0065902 5777800.0 33030.0 33270.0 50942.0 46462.0 48587.0 54496.0 47181.0 50275.0 56740.0 44865.0 True False 43532.852933320406 44023.876869689986 50266.475795088525 35750.9037307443 41841.53372266806 51088.356505110074 51380.01759829196 42506.15395456895 59739.16056299417 43294.29000584321 1.0055102630726822 1.0168518034075233 1.1610416936807213 0.8257648693608136 0.9664446216122475 1.1800252758092333 1.1867619861962735 0.9817958430276166 1.3798392479685306 1.0 15.401889142989637 -6.760698906047662 24.99907744103123 1.1471140660854553 0.9961387732051962 0.25745534180277163 0.12783099654895994 28.584814257912694 965063.4052888395 0.04235583333587439 0.03999110608106862 1.735006451215645e-07 6.760698906047662 -0.15097529288025913 NNRPAFFSPS(ph)LK ddPTM_PC-9_Lapatinib_30min_R1 2 NNRPAFFSPSLK 12 1 Q6ICG6-2;B0QY16;Q6ICG6-3;Q6ICG6 Q6ICG6-2 KIAA0930 Uncharacterized protein KIAA0930 1 NNRPAFFS(0.114)PS(0.886)LK;NNRPAFFS(0.12)PS(0.88)LK 60.901 0.027389999999999998 13224100.0 86754.0 93233.0 77329.0 83562.0 89866.0 90225.0 85120.0 104903.0 81688.0 79813.0 True False 85516.87205126495 93017.1247167183 70971.30811857221 89707.4282346603 84580.25856335385 86366.28707474763 89527.09710464133 109777.17634722979 72487.43722722503 93608.57070586254 0.9135581433026749 0.9936817111437084 0.7581710476231788 0.9583249435197506 0.9035525051346259 0.9226322592418202 0.9563985052816794 1.172725697224588 0.7743675251168564 1.0 16.514353007101377 -7.336712906486391 4.04404295504942 0.9933384229229018 0.907078972232944 0.0851538221068775 0.10644668748266739 0.5040241029404461 15.804216947074597 0.04450830348418317 0.02942505890756834 4.60560930111218e-08 7.336712906486391 -0.08625945068995777 NNRPSEGPLQTR ddPTM_PC-9_Lapatinib_30min_R1 2 NNRPSEGPLQTR 12 1 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 ; 92.792 0.0073479 7513400.0 18743.9 23671.2 26287.6 19467.9 26662.0 22788.0 20914.4 23332.3 21874.0 20367.5 False True 18476.608548789733 23616.390790754183 24126.335001070474 20899.634309010606 25093.793579508827 21813.410361422546 21997.24529705485 24416.403836748876 19410.319776568413 23887.995237012172 0.7734683620566865 0.9886300862184884 1.00997738662008 0.8749011418349839 1.0504771677377256 0.9131536633775256 0.9208493671738605 1.022120257246116 0.812555410530808 1.0 14.543998162477994 -4.754993308496566 24.985370068447203 0.9552960161711923 0.7734680556103136 0.37433242979599235 0.07030317523797158 222.16277885745933 861035.9277895776 0.01625022296218855 0.15024945604380874 1.7579506998255694e-05 4.754993308496566 -0.1818279605608787 NNS(ph)FTAPSTVGK ddPTM_PC-9_AZD4547_30min_R2 1 NNSFTAPSTVGK 12 0 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;O95453-4 O95453 PARN Poly(A)-specific ribonuclease PARN 1 NNS(0.986)FT(0.014)APSTVGK 136.83 6.4567e-05 19884000.0 32874.0 34054.0 43409.0 61378.0 60979.0 45810.0 56584.0 63986.0 61137.0 49857.0 True False 43327.248178322 45061.28953773435 42833.36829706324 47228.25038064702 52513.118424158245 42945.49345821878 61619.86638226735 54098.4339520049 64368.577006340754 48111.52160528975 0.9005586756075132 0.9366007981917571 0.8902933615043639 0.9816411704479199 1.0914873749988516 0.8926238876946477 1.2807715143121223 1.1244382249190161 1.3379035802364558 1.0 15.5540948072733 -7.258043830278096 24.999775463107703 1.196148184988356 0.9536199284858184 0.5692537101162825 0.1007475510053957 207.7003525997789 1529203.891139387 0.03796647384671413 0.02818145202446108 5.520217248112177e-08 7.258043830278096 -0.2425282565025375 NNS(ph)FTAPSTVGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NNSFTAPSTVGK 12 0 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;O95453-4 O95453 PARN Poly(A)-specific ribonuclease PARN 1 NNS(0.967)FT(0.033)APSTVGK;NNS(0.978)FT(0.021)APSTVGK 130.47 0.00014507 28420000.0 70016.0 82985.0 54082.0 73856.0 80077.0 65260.0 82632.0 113063.0 70497.0 57719.0 True False 81868.32592096491 91223.2023712413 55371.51998712713 69718.08776438265 64386.48668755433 61837.65071633583 74804.49875612692 110095.21605015098 71527.8852577789 68182.99779664737 1.2007146732552505 1.3379171541167827 0.8121015762942857 1.0225142633404536 0.9443188004080437 0.906936519581667 1.0971136672404442 1.6147018994164037 1.0490575006852514 1.0 16.05712441128426 -7.540172836760543 24.994396411832657 1.2703093968344712 1.033100398006711 0.12182853775596691 0.20841919518433483 391.7916775806533 566232.5198556249 0.09740042591179623 0.05624856665924967 2.8828839695785134e-08 7.540172836760543 -0.23720899882776014 NNS(ph)FTAPSTVGK ddPTM_PC-9_Lapatinib_30min_R1 2 NNSFTAPSTVGK 12 0 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;O95453-4 O95453 PARN Poly(A)-specific ribonuclease PARN 1 NNS(0.504)FT(0.496)APSTVGK;NNS(0.977)FT(0.023)APSTVGK 150.26 0.00017245 33332000.0 65129.0 118819.0 105357.0 102419.0 163458.0 138412.0 176028.0 149360.0 120609.0 169291.0 True False 64200.2485168042 118543.88190571785 96694.95414978116 109951.23491976847 153843.72181079246 132492.44141413117 185141.86852838108 156299.81086548712 107024.74435092534 198552.72378392174 0.3233410617256058 0.5970398171657679 0.4869988802319883 0.5537634177178284 0.7748255419463065 0.6672909788853778 0.9324569565203484 0.7871955009571309 0.5390243070520492 1.0 17.59916262659913 -6.073306104244784 1.0146441336824898 0.7946862879959546 0.438758473822197 0.5442050153549753 0.13367149885197877 0.4614306647557164 0.9772308760893195 0.056284962816313046 0.1089937166750475 8.446832762789932e-07 6.073306104244784 -0.35592781417375763 NNS(ph)FTAPSTVGKR ddPTM_PC-9_AZD4547_30min_R2 1 NNSFTAPSTVGKR 13 1 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;O95453-4 O95453 PARN Poly(A)-specific ribonuclease PARN 1 NNS(0.967)FT(0.033)APSTVGKR 70.45100000000001 0.012916999999999998 12471000.0 13191.0 13658.0 15357.0 37567.0 25962.0 13091.0 19484.0 29476.0 12385.0 21463.0 True False 17385.463610155297 18072.681403252955 15153.356145914457 28906.50855436422 22357.624436740454 12272.41770053574 21218.03825449061 24921.161491096438 13039.645815521379 20711.58690282877 0.839407607525274 0.8725879618999451 0.7316366542558275 1.395668457949796 1.079474235442909 0.5925387445256347 1.0244525614593378 1.2032473227675629 0.6295821694734764 1.0 14.338150475316116 NNS(ph)FTAPSTVGKR ddPTM_PC-9_Lapatinib_30min_R1 2 NNSFTAPSTVGKR 13 1 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;O95453-4 O95453 PARN Poly(A)-specific ribonuclease PARN 1 NNS(0.999)FT(0.001)APSTVGKR;NNS(0.975)FT(0.025)APSTVGKR 145.1 1.1029e-06 2648800.0 53032.0 22898.0 20554.2 21344.4 28475.0 25999.0 21033.0 14781.8 26625.0 26618.0 True False 52275.75395512226 22844.98108784894 18864.31301750647 22914.1383788311 26800.15648400396 24887.083376629125 22121.9858247406 15468.616391613958 23626.212126320464 31218.88583374444 1.6744913394256205 0.7317679820320763 0.6042596496866671 0.7339832209534924 0.8584597357742895 0.7971803833475928 0.7086090753702998 0.4954890598592073 0.7567922907992742 1.0 14.930131429651484 -4.761477960279261 9.59177013624374 0.7264936396574195 1.6793680041582 0.8235501177953518 0.12915718397312853 0.02935805008389087 48.15526831346506 0.032004524952314914 0.18165636427468124 1.731896919400591e-05 4.761477960279261 0.9528743645007804 NNS(ph)GEEFDCAFR ddPTM_PC-9_AZD4547_30min_R2 2 NNSGEEFDCAFR 12 0 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 NNS(1)GEEFDCAFR;NNS(1)GEEFDCAFR 157.23 0.00028118 8098500.0 12875.7 11884.400000000001 14379.3 19498.6 16894.3 19824.0 13289.9 14676.800000000001 13318.5 16693.5 True False 16969.904768802724 15725.799887891295 14188.621086732277 15003.499020366975 14548.818061845164 18584.402146163062 14472.675354052288 12408.837799312127 14022.488719743356 16109.06564610594 1.0534381783281686 0.9762080702484881 0.8807848573242425 0.9313699099608415 0.9031447497615769 1.1536610846610764 0.8984180505559477 0.770301522876451 0.8704718838322585 1.0 13.975585197192848 -7.510920048977097 24.984924674476115 0.859103965696374 0.9766419697330171 0.21090440767508567 0.09041039520335303 797.1217978478793 1665411.1211982607 0.0398571515952565 0.025218073929251055 3.083755599003947e-08 7.510920048977097 0.11753800403664305 NNS(ph)GEEFDCAFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NNSGEEFDCAFR 12 0 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 NNS(1)GEEFDCAFR;NNS(1)GEEFDCAFR 167.92 0.00038496 6537600.0 12648.5 14781.8 12849.0 15809.3 17648.800000000003 12500.5 14875.5 14696.5 15969.9 12542.5 True False 14789.641230737621 16249.239414487094 13155.368890103855 14923.556175442149 14190.644332970873 11844.951774127436 13466.384950706353 14310.732447228891 16203.42957541747 14816.35596362464 0.9981969430977087 1.0967095724738458 0.8878950345416482 1.0072352616311795 0.9577688581328675 0.7994510798206899 0.9088864349484735 0.9658739626911573 1.09361772997343 1.0 13.854903044490458 -5.258218676897607 24.98215867598261 0.9464785959933889 1.0474532561130574 0.19021308430605066 0.07747525951392459 440.06974335284247 3413463.5846720166 0.020701251470400046 0.05018295500521957 5.517995260271109e-06 5.258218676897607 0.10097466011966849 NNS(ph)GEEFDCAFR ddPTM_PC-9_Lapatinib_30min_R1 2 NNSGEEFDCAFR 12 0 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 NNS(1)GEEFDCAFR;NNS(1)GEEFDCAFR 136.33 6.308e-05 7842100.0 17290.0 15647.900000000001 17585.6 14407.900000000001 17795.0 18240.8 14839.900000000001 16052.7 17609.0 17577.1 True False 17043.441429402315 15611.668248954109 16139.779850379076 15467.505029345431 16748.333086316077 17460.68350538162 15608.237409811645 16798.567045262513 15625.688989009479 20615.278314986463 0.8267383621501938 0.7572863199040619 0.7829038057975728 0.7502932918495303 0.8124233313959544 0.8469778209440141 0.7571198977442423 0.8148600658498335 0.7579664339360503 1.0 14.33142631790084 -10.854238494164141 3.126898423676625 1.0017068819893653 0.7894580147080766 0.7910736363578458 0.03243508539979043 19096163.32500633 25010755.6272893 300646.9491958488 0.007936899052136284 1.398818945843289e-11 10.854238494164141 -0.21224886728128867 NNS(ph)NTCNIENELEDSR ddPTM_PC-9_Lapatinib_30min_R1 2 NNSNTCNIENELEDSR 16 0 Q6PL18;A0A0B4J211 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 NNS(0.999)NT(0.001)CNIENELEDSR;NNS(0.506)NT(0.494)CNIENELEDSR 104.26 0.0066118999999999995 0.0 23346.0 18394.9 43134.0 20680.6 23325.0 23303.6 19509.5 18279.9 36709.0 19775.9 True False 23013.08175886794 18352.30773922929 39587.68902205501 22201.520312459226 21953.069358714387 22306.959351344853 20519.606449283358 19129.250888055845 32574.44585709291 23194.137965269634 0.9921938807696666 0.7912476750250262 1.7067971692387405 0.9572039428972644 0.9464921434711825 0.9617498776952512 0.8846893331413714 0.8247450677709834 1.4044258038763557 1.0 14.50147260744269 NNS(ph)NTCNIENELEDSRK ddPTM_PC-9_AZD4547_30min_R2 1 NNSNTCNIENELEDSRK 17 1 Q6PL18;A0A0B4J211 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 NNS(0.988)NT(0.012)CNIENELEDSRK 103.4 0.00039828 9343700.0 6966.5 6828.9 7041.7 13611.0 9504.6 10241.0 8979.0 11448.0 11391.0 9483.1 True False 9181.702087798261 9036.208378582076 6948.322457034952 10473.194237853733 8185.05035133824 9600.628651072228 9778.11360537216 9678.974648869316 11993.105004812596 9151.099555430997 1.0033441371915905 0.9874450959523507 0.7592882598366291 1.1444738606999525 0.894433537932671 1.0491229598059004 1.068517891882079 1.0576843351163232 1.310564367939252 1.0 13.15972938629493 -7.2908478643407815 1.2249161043709063 1.1413322435492428 0.9556740839831471 0.2694950506391248 0.11764347158067132 0.6063661122131575 1.7639981730022778 0.07560718592083182 0.04224079025525783 5.118611117986165e-08 7.2908478643407815 -0.18565815956609566 NNS(ph)NTCNIENELEDSRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NNSNTCNIENELEDSRK 17 1 Q6PL18;A0A0B4J211 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 NNS(0.998)NT(0.002)CNIENELEDSRK 88.87200000000001 0.0012157 10290000.0 13393.0 10553.0 9905.1 12080.0 11624.0 12042.0 16775.0 11940.0 8134.8 10213.0 True False 15660.170376192358 11600.632097652671 10141.275149300938 11403.19676388842 9346.360643582191 11410.49632127055 15185.95055951726 11626.587651475727 8253.756060470389 12064.536053936483 1.2980333687247485 0.9615481312990526 0.8405855893639597 0.945183197506192 0.774697062680053 0.9457882400332726 1.2587264434890808 0.9636995239184636 0.6841337307601901 1.0 13.558484816814293 -4.765350339173747 4.928300603152126 0.9311520082674138 1.3212452125701066 0.371425154384012 0.14396236709369878 0.2009469495768824 12.533920756864159 0.03766730381842197 0.27173916640264784 1.7165231337336937e-05 4.765350339173747 0.3900932043026928 NNS(ph)NTCNIENELEDSRK ddPTM_PC-9_Lapatinib_30min_R1 2 NNSNTCNIENELEDSRK 17 1 Q6PL18;A0A0B4J211 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 NNS(1)NTCNIENELEDSRK;NNS(0.984)NT(0.016)CNIENELEDSRK 139.7 3.7542e-05 19592600.0 27878.0 27483.0 25325.0 37500.0 27554.0 24008.0 27079.0 30426.0 29015.0 23671.0 True False 27480.454607800915 27419.364802050473 23242.876257327018 40257.87509633284 25933.327893248283 22981.233805381453 28481.01812143541 31839.703035573897 25747.025158504755 27762.500810375117 0.9898407494158884 0.9876403062293145 0.8372039830302653 1.4500810057171825 0.9341135393522166 0.8277796716639138 1.0258808569144382 1.146860048849601 0.9274029502732276 1.0 14.760849909433336 NNS(ph)PPTVGAFGHTR ddPTM_PC-9_AZD4547_30min_R2 4 NNSPPTVGAFGHTR 14 0 Q86XL3;F5H1D4;Q86XL3-3 Q86XL3 ANKLE2 Ankyrin repeat and LEM domain-containing protein 2 1 NNS(1)PPTVGAFGHTR;NNS(1)PPTVGAFGHTR;NNS(0.999)PPT(0.001)VGAFGHTR;NNS(1)PPTVGAFGHTR 149.12 9.4505e-05 29457100.0 111604.0 89766.0 126512.0 155344.0 176967.0 138789.0 125520.0 131451.0 129717.0 121325.0 True False 147091.75049259097 118781.10403019514 124834.36821852767 119531.8408408751 152398.18672277385 130110.5018898214 136691.03683553977 111138.26839347655 136573.575797496 117077.44867845596 1.2563627936287454 1.0145515244051666 1.0662546000756772 1.0209638336855114 1.3016869469142904 1.1113199284617117 1.167526610619531 0.949271355397478 1.166523334246757 1.0 16.83710368680069 -8.69215006776606 0.7138953798618217 1.0053854368988866 1.122035373898498 0.09735885429259405 0.10465908970725955 2.3827772888674343 2.5942455856979105 0.10486164296633625 0.03944104853423029 2.031654863887804e-09 8.69215006776606 0.11664993699961146 NNS(ph)PPTVGAFGHTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NNSPPTVGAFGHTR 14 0 Q86XL3;F5H1D4;Q86XL3-3 Q86XL3 ANKLE2 Ankyrin repeat and LEM domain-containing protein 2 1 NNS(0.999)PPT(0.001)VGAFGHTR;NNS(1)PPTVGAFGHTR;NNS(1)PPTVGAFGHTR;NNS(0.897)PPT(0.103)VGAFGHTR 143.69 9.5394e-05 23857100.0 83173.0 69914.0 73563.0 98693.0 114119.0 101249.0 98737.0 88035.0 84765.0 76173.0 True False 97252.5461583698 76854.59987447051 75317.02090923123 93163.55117702315 91758.20116009598 95939.32420132222 89383.91656602424 85724.17453079265 86004.52776537498 89982.56191486365 1.0807932569244316 0.8541054870963325 0.8370179655530577 1.0353511746550312 1.0197331483728185 1.066199074128324 0.9933470959694857 0.9526754151754421 0.9557910547906776 1.0 16.45735782236386 -5.783416623974477 24.999927234221264 1.0042185734186677 0.9169854984905397 0.2161468517955455 0.06882669506645227 328.1625361118825 373295.8578218148 0.019928899024850715 0.029585558602069458 1.6465820474560074e-06 5.783416623974477 -0.08723307492812804 NNS(ph)PPTVGAFGHTR ddPTM_PC-9_Lapatinib_30min_R1 3 NNSPPTVGAFGHTR 14 0 Q86XL3;F5H1D4;Q86XL3-3 Q86XL3 ANKLE2 Ankyrin repeat and LEM domain-containing protein 2 1 NNS(1)PPTVGAFGHTR;NNS(0.998)PPT(0.002)VGAFGHTR;NNS(0.969)PPT(0.03)VGAFGHT(0.001)R 122.13 3.5249e-05 12319900.0 105866.0 88351.0 72676.0 63028.0 62655.0 73176.0 51967.0 49617.0 72021.0 46745.4 True False 104356.33142655344 88146.42868776928 66700.85981747275 67663.28937524448 58969.75608446947 70046.4330615875 54657.596983516174 51922.386955763825 63909.23656524798 54825.28010566977 1.9034345328545144 1.6077697828059723 1.2166077344048967 1.2341622194146722 1.0755942508786398 1.2776301904263982 0.9969414999461853 0.9470519230488027 1.1656891937819536 1.0 15.74255365728331 -1.5228791714001655 0.5094173480649598 1.042547982859737 31.870231881473842 0.8948638773104082 0.09241794868112335 32.040841256966885 0.33160941185969733 0.04966446696740027 1061.91581512635 0.02999997056469953 1.5228791714001655 30.827683898614104 NNS(ph)RVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NNSRVER 7 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 NNS(1)RVER 97.602 0.021717 0.0 13517.0 20222.0 14742.0 14551.0 22977.0 15805.0 16057.0 13229.0 15429.0 14459.0 True False 15805.161127080717 22229.50651745782 15093.505189346331 13735.754644978499 18474.821791774604 14976.157976887655 14535.964717387104 12881.752767284119 15654.619936199742 17080.302242618975 0.9253443471066625 1.3014703253898219 0.8836790458944478 0.804186860973975 1.0816448988634408 0.8768087217753656 0.8510367387479122 0.7541876358101799 0.916530616017915 1.0 14.060045883785929 -5.301697830021047 24.627400156350124 0.8882888172417328 1.1134073675260039 0.33675182330993336 0.1216535959296102 388.536037357273 237679.36730957296 0.03073745138710068 0.06398668430781294 4.992317181447669e-06 5.301697830021047 0.22511855028427108 NNS(ph)TAYSTRGNRIEISY(ph)ENLQVTNITRK ddPTM_PC-9_AZD4547_30min_R2 1 NNSTAYSTRGNRIEISYENLQVTNITRK 28 3 Q8TAM1 Q8TAM1 BBS10 Bardet-Biedl syndrome 10 protein 2 NNS(0.242)T(0.242)AY(0.224)S(0.242)T(0.049)RGNRIEIS(0.182)Y(0.753)ENLQVT(0.034)NIT(0.03)RK 42.45399999999999 0.016557 6739400.0 1343.7 0.0 38470.0 34358.0 27783.0 27638.0 7516.9 58924.0 19194.0 17078.0 True False 1770.9686493037439 0.0 37959.862664148524 26437.29392580845 23925.810019488494 25909.79149090266 8185.889537835168 49818.64973881692 20208.555654672375 16480.10441813863 0.10746100900638397 0.0 2.303375130461458 1.6041945642474544 1.4517996617275577 1.5721861241598296 0.4967134509673049 3.022957165488868 1.2262395396251293 1.0 14.008437763032568 -5.246150164724542 24.59542708041695 1.613580272695052 0.05373006675942526 0.4671550334538611 0.6534381543248091 538.5604208700809 866365.9503846181 0.1603106217786587 0.4205384285163108 5.673484011035069e-06 5.246150164724542 -1.559850205935627 NNS(ph)VSGLSVK ddPTM_PC-9_Lapatinib_30min_R1 2 NNSVSGLSVK 10 0 Q9UHI6;E9PJ60 Q9UHI6 DDX20 Probable ATP-dependent RNA helicase DDX20 1 NNS(0.992)VS(0.007)GLS(0.001)VK;NNS(0.994)VS(0.005)GLSVK 98.902 0.010768999999999999 3774900.0 38125.0 50009.0 39818.0 34727.0 36964.0 46964.0 50591.0 42982.0 43701.0 54067.0 True False 37581.33050873126 49893.207233043795 36544.31774192485 37280.939425876 34789.85019402012 44955.459198431134 53210.35443633584 44979.1006335055 38778.933188068775 63412.40891025099 0.5926494696317398 0.7868051078718484 0.576296002153882 0.5879123670990098 0.5486284276514235 0.7089378872525977 0.839115803212044 0.7093107075803639 0.6115354053644843 1.0 15.952477562525441 -6.982154458625589 9.351523095610805 0.7669820701349473 0.6241418120552089 0.33837316454320165 0.11124152582693474 0.3275503851821936 155.53519991460232 0.03916743244049536 0.034140241430769346 1.0419467908095352e-07 6.982154458625589 -0.14284025807973844 NNS(ph)YTCYTAAICGLPVHATFR ddPTM_PC-9_AZD4547_30min_R2 2 NNSYTCYTAAICGLPVHATFR 21 0 Q08357 Q08357 SLC20A2 Sodium-dependent phosphate transporter 2 1 NNS(0.823)Y(0.064)T(0.113)CYTAAICGLPVHATFR;NNS(0.552)Y(0.202)T(0.247)CYTAAICGLPVHATFR 113.02 5.9619000000000005e-06 10893800.0 1889.3 2649.6 14049.4 17373.0 12041.0 7895.900000000001 10763.2 17903.5 11298.3 12168.3 True False 2490.0581001187484 3506.0313842479873 13863.095776285116 13367.923260174337 10369.314992789145 7402.168124792623 11721.103948918764 15136.925456501742 11895.505072063394 11742.29152074226 0.21205895763362428 0.2985815313863339 1.1806124683411705 1.1384424612998636 0.8830742257141369 0.6303853137794277 0.9981956186502381 1.2890946737068318 1.0130480112038174 1.0 13.51942635895215 -5.250705160480282 23.269807131058435 1.012062516707456 0.25531980366497037 0.7632858056116415 0.16956565858072142 142.1069302400366 308056.96321192227 0.04815304175164724 0.12418382569148756 5.614289969441858e-06 5.250705160480282 -0.7567427130424855 NNSFT(ph)APSTVGK ddPTM_PC-9_AZD4547_30min_R2 3 NNSFTAPSTVGK 12 0 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;O95453-4 O95453 PARN Poly(A)-specific ribonuclease PARN 1 NNS(0.018)FT(0.981)APSTVGK;NNS(0.055)FT(0.945)APSTVGK;NNS(0.098)FT(0.901)APSTVGK 149.3 0.00013795 60525000.0 151748.0 170620.0 165771.0 213786.0 167152.0 182324.0 226684.0 308993.0 242821.0 177997.0 True False 200000.70744551957 225769.57834404882 163572.7682271529 164500.9406607744 143945.83005354155 170923.2514576794 246858.43685490443 261245.23180276668 255656.0223311036 171765.3792080701 1.1643831158969833 1.3144067761790346 0.9523034792069885 0.9577072016445418 0.8380375062612064 0.9950972206723301 1.437183895806322 1.520942305179579 1.4884025145801443 1.0 17.390079752600386 -7.261987344315156 24.999884061424748 1.4050440532349826 1.0331027589928286 0.4237862021467821 0.18263326017525505 45.11795223088216 2058348.232088075 0.07595133993926814 0.05471074576535857 5.4703190360422496e-08 7.261987344315156 -0.37194129424215405 NNSFT(ph)APSTVGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NNSFTAPSTVGK 12 0 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;O95453-4 O95453 PARN Poly(A)-specific ribonuclease PARN 1 NNS(0.037)FT(0.963)APSTVGK 141.54 0.00019250000000000002 12036000.0 48065.0 61020.0 30329.0 54487.0 49348.0 32132.0 60559.0 90464.0 47108.0 34201.0 True False 56201.45517297734 67077.66233286893 31052.15838337301 51434.27003923744 39678.61364758205 30446.941354846804 54822.413110808106 88089.41585453111 47796.865380419826 40401.37056503296 1.3910779358960466 1.6602818516984688 0.7685917073874813 1.2730823068599897 0.9821105841870512 0.7536115960679406 1.3569443893632767 2.1803571171610634 1.1830505923922197 1.0 15.302116614948229 -7.521701143627049 24.998444272627996 1.5627524255613892 1.13670374453697 0.10492315140244302 0.38805976560370103 74.92411186032705 1590625.731873768 0.17780413537923187 0.10440335118400922 3.008145622588143e-08 7.521701143627049 -0.42604868102441906 NNSFT(ph)APSTVGK ddPTM_PC-9_Lapatinib_30min_R1 2 NNSFTAPSTVGK 12 0 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;O95453-4 O95453 PARN Poly(A)-specific ribonuclease PARN 1 NNS(0.229)FT(0.771)APSTVGK;NNS(0.304)FT(0.696)APSTVGK 134.06 0.00013752 35032000.0 67645.0 128512.0 95907.0 113836.0 176474.0 152063.0 194545.0 182680.0 170661.0 196963.0 True False 66680.36989542618 128214.43835975374 88021.89667172603 122207.8791857641 166094.1462812333 145559.61996616612 204617.58818400404 191167.97970612757 151439.36103999926 231007.79211329905 0.2886498731727734 0.5550221366423443 0.38103431865430415 0.5290205930621881 0.7189980249660648 0.6301069701353433 0.8857605464825542 0.8275390970897128 0.6555595361290887 1.0 17.817581990379516 -5.469127625790943 0.25530948751813604 0.977658933563092 3.5134661014757566e-16 0.7675252588741033 0.10128539097497001 3.306305060044507 0.24707897711236393 0.15436475258407675 1.002945056038689 3.3952548183184413e-06 5.469127625790943 -0.9776589335630916 down NNSGEEFDCAFR ddPTM_PC-9_Lapatinib_30min_R1 1 NNSGEEFDCAFR 12 0 Q08J23;Q08J23-3;Q08J23-2 Q08J23 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 0 91.12299999999999 0.030297 3993500.0 9955.8 15950.0 13478.0 18494.0 11891.0 20765.0 11413.0 9970.0 17247.0 14398.0 False True 9813.82846632988 15913.068754965083 12369.890866584543 19854.110454175454 11191.594758605486 19876.92935557923 12003.909295762121 10433.242597274426 15304.461241038476 16886.675115870927 0.581158126095904 0.9423446975662604 0.7325237669171898 1.175726442176624 0.662747087973942 1.1770777384648037 0.7108509646449145 0.6178387708465328 0.9063040021806656 1.0 14.043597677727623 -12.249401944309534 0.01279679866645098 1.8445484756588402 6.48784061801605e-06 0.03813927770279091 0.20611342012956402 33425.63114295383 49.32855333536069 4030.6097645873947 3127.437780179221 5.631162443126263e-13 12.249401944309534 -1.844541987818222 NNSNT(ph)CNIENELEDSRK ddPTM_PC-9_AZD4547_30min_R2 1 NNSNTCNIENELEDSRK 17 1 Q6PL18;A0A0B4J211 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 NNS(0.307)NT(0.693)CNIENELEDSRK 69.986 0.013016999999999999 10684000.0 14181.0 10981.0 14711.0 20723.0 15999.0 18507.0 15782.0 12231.0 16215.0 19200.0 True False 18690.263016876077 14530.39350484117 14515.922528003355 15945.632517158409 13777.81501284226 17349.75436435834 17186.56742621488 10340.97999041934 17072.091796421417 18527.813844025175 1.0087678543307088 0.7842475980795172 0.7834665573717663 0.8606321636969887 0.743628748044946 0.9364167035795897 0.9276090299103033 0.5581327660928591 0.9214304472260662 1.0 14.177405042757647 -4.753866914696455 24.78650423914528 0.8236430616085075 1.0087682227474075 0.1514078525708895 0.12067449029147705 434.9522862536974 1423572.201636459 0.028722048686054387 0.2940922729516168 1.7625160695053636e-05 4.753866914696455 0.18512516113889999 NNSQIASGQNQPQAAAGSHQLS(ph)MGQPHNAAGPSPHTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLR 38 0 Q68EM7-6;Q68EM7-5;Q68EM7;Q68EM7-7;Q68EM7-3;Q68EM7-2 Q68EM7-6 ARHGAP17 Rho GTPase-activating protein 17 1 NNSQIASGQNQPQAAAGS(0.056)HQLS(0.472)MGQPHNAAGPS(0.358)PHT(0.114)LR;NNSQIASGQNQPQAAAGS(0.159)HQLS(0.718)MGQPHNAAGPS(0.102)PHT(0.021)LR 79.801 7.8417e-10 25159000.0 21729.7 47219.0 162104.0 135413.0 188674.0 140391.0 133998.0 120872.0 125352.0 86249.0 True False 25408.109028861873 51906.59026050048 165969.17414284326 127826.24862486948 151704.68410764183 133028.6488157693 121304.73937849114 117699.23807447005 127185.03585731471 101885.26095329183 0.24937963343402475 0.5094612289828309 1.6289811950222122 1.2546098172479532 1.4889757624234694 1.30567117923715 1.19060144954727 1.1552135900052114 1.248316338077804 1.0 16.636585836170426 -5.128519769386808 4.999796334778043 1.291289931965566 0.31095791684029556 0.8255814304704227 0.16771946534713378 0.07830384175285032 2.7868090590504178 0.0427244281522458 0.12242124474965026 7.4384120196813324e-06 5.128519769386808 -0.9803320151252704 down NNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPS(ph)PHTLR ddPTM_PC-9_AZD4547_30min_R2 2 NNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLR 38 0 Q68EM7-6;Q68EM7-5;Q68EM7;Q68EM7-7;Q68EM7-3;Q68EM7-2 Q68EM7-6 ARHGAP17 Rho GTPase-activating protein 17 1 NNSQIASGQNQPQAAAGS(0.074)HQLS(0.283)MGQPHNAAGPS(0.577)PHT(0.066)LR;NNSQIASGQNQPQAAAGS(0.102)HQLS(0.102)MGQPHNAAGPS(0.698)PHT(0.099)LR 58.867 5.5122e-05 30676000.0 4996.4 10440.9 42665.0 81031.0 65336.0 58344.0 39484.0 93113.0 52445.0 72833.0 True False 6585.151268423922 13815.71674207231 42099.23422318422 62350.55486647029 56265.224181452715 54695.74045680673 42997.999509356756 78724.5253738793 55217.13563141049 70283.13883863986 0.09369460979172398 0.19657227850610431 0.5989947933292806 0.8871338972156371 0.800550816471497 0.7782199452187303 0.6117825728881301 1.1201054289083425 0.7856384410801746 1.0 16.100891002964886 -5.354743644246516 2.1523747427983664 0.8456927960140896 0.09310753676264852 0.8240429354967124 0.13013651208793076 0.1309440974630288 1.1396337347668746 0.036796788265255245 0.11643904222127618 4.418311749141803e-06 5.354743644246516 -0.7525852592514412 down NNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPS(ph)PHTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLR 38 0 Q68EM7-6;Q68EM7-5;Q68EM7;Q68EM7-7;Q68EM7-3;Q68EM7-2 Q68EM7-6 ARHGAP17 Rho GTPase-activating protein 17 1 NNSQIASGQNQPQAAAGS(0.01)HQLS(0.03)MGQPHNAAGPS(0.858)PHT(0.102)LR 66.91 1.4117e-06 7663800.0 2543.1 3963.4 7569.6 8813.7 12027.0 11319.0 11226.0 8259.6 9013.3 7517.4 True False 2973.596601485462 4356.860158801917 7750.087971867866 8319.89696340094 9670.395686541897 10725.411714039308 10162.592010798255 8042.794251769596 9145.102461011678 8880.245112294348 0.3348552392285474 0.4906238627096021 0.872733564655572 0.9368994727276585 1.0889784644743215 1.2077832963405932 1.1444044485583567 0.9056950737355961 1.0298254547445596 1.0 13.116383783018001 -5.244086906404519 1.377606706226144 1.0646142652601347 0.2603715238246897 0.906549435165912 0.08123329796170717 0.18741521416095203 0.5435845012842572 0.02766597381169368 0.16540868987968826 5.7005018847015054e-06 5.244086906404519 -0.8042427414354449 down NNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPS(ph)PHTLR ddPTM_PC-9_Lapatinib_30min_R1 1 NNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLR 38 0 Q68EM7-6;Q68EM7-5;Q68EM7;Q68EM7-7;Q68EM7-3;Q68EM7-2 Q68EM7-6 ARHGAP17 Rho GTPase-activating protein 17 1 NNSQIASGQNQPQAAAGS(0.208)HQLS(0.055)MGQPHNAAGPS(0.499)PHT(0.237)LR 49.073 0.0015040999999999998 7943600.0 24919.0 26604.0 54735.0 38147.0 51171.0 48776.0 31706.0 38867.0 62113.0 34828.0 True False 24563.650490415068 26542.400072544882 50234.899583210055 40952.457634661565 48161.22238605678 46689.96418240942 33347.581541350526 40672.90271095943 55117.17986111338 40847.97339460711 0.6013431866771155 0.6497849921741553 1.2298015154368036 1.0025578806332716 1.1790357852224609 1.1430178856455482 0.816382766880503 0.9957140913220731 1.3493247101553916 1.0 15.317976882741018 -5.245700513587313 21.958420754551653 1.0815789803687397 0.6255633721121341 0.633759719645681 0.14096271308885688 104.38626022399775 145632.68393663666 0.036199306286448664 0.09469750227457238 5.679361151425718e-06 5.245700513587313 -0.4560156082566056 NNTQVLINCR ddPTM_PC-9_Lapatinib_30min_R1 2 NNTQVLINCR 10 0 K7ERG4;P62316-2;P62316 K7ERG4 SNRPD2 Small nuclear ribonucleoprotein Sm D2 0 ; 128.91 0.0012165999999999998 5979600.0 45667.0 41360.0 37789.0 31992.0 43572.0 35990.0 41856.0 41675.0 31839.0 45089.0 False True 45015.78020569786 41264.23346115084 34682.13428975838 34344.798402183456 41009.18062584796 34450.791596787654 44023.09887701912 43611.37264206738 28252.956540466395 52882.57357268401 0.8512403456277766 0.780299268235037 0.6558329511344567 0.6494539898853171 0.7754762647752618 0.6514583022219419 0.8324689193976527 0.8246832499958818 0.5342583507520555 1.0 15.690504768010069 -7.277228833260255 24.6329762837059 0.7832428915056797 0.7251066226541385 0.06846884777636086 0.12270156464647575 2493.9906389702446 3890835.6647322928 0.05019256270005657 0.03396937157591023 5.281668830598041e-08 7.277228833260255 -0.05813626885154122 NNTVIDELPFKS(ph)PITK ddPTM_PC-9_AZD4547_30min_R2 1 NNTVIDELPFKSPITK 16 1 Q9UQC2-2;Q9UQC2 Q9UQC2-2 GAB2 GRB2-associated-binding protein 2 1 NNT(0.071)VIDELPFKS(0.758)PIT(0.171)K 64.295 0.014367 11628000.0 34188.0 36910.0 32793.0 48359.0 50214.0 42924.0 33275.0 37302.0 43601.0 45146.0 True False 45059.0728454241 48840.43568561037 32358.143393434428 37210.579689102145 43242.65285673237 40239.95549444626 36236.41053778355 31537.833014685817 45905.6598467943 43565.45228137295 1.0342845187146095 1.1210818005553638 0.7427477897955768 0.8541304575187912 0.9925904723183926 0.9236666529834568 0.8317694099385481 0.7239184115659987 1.0537170497004558 1.0 15.410896900341143 -5.242821346835671 24.960543654367733 0.8819177147840076 1.077683187740497 0.3381457144002812 0.10432440129220323 861.516993776718 1155001.4398177275 0.026188849259003985 0.06901228864468724 5.717137708339029e-06 5.242821346835671 0.1957654729564895 NNTVIDELPFKS(ph)PITK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NNTVIDELPFKSPITK 16 1 Q9UQC2-2;Q9UQC2 Q9UQC2-2 GAB2 GRB2-associated-binding protein 2 1 NNTVIDELPFKS(0.827)PIT(0.173)K 56.851000000000006 0.028263999999999997 4852800.0 6942.5 5814.6 5471.9 9656.6 22535.0 27492.0 32210.0 35349.0 29444.0 25790.0 True False 8117.728129374703 6391.83506064733 5602.370848296308 9115.57200911961 18119.42851885106 26050.27112309998 29158.8356197944 34421.12620536142 29874.562797424645 30465.522846472315 0.266456222342978 0.20980552649164388 0.18389216152727286 0.2992094393080514 0.5947519302446226 0.8550738240855896 0.9571093122785773 1.129838682855467 0.9806023335944126 1.0 14.894889879515373 -6.5950000145899494 1.37923570517714 1.03557561994763 0.20790055374018196 0.9822175227969151 0.04775752255375431 0.04874349689248827 0.19264180591066823 0.021161246763501975 0.022129135641260397 2.5409726201863446e-07 6.5950000145899494 -0.8276750662074481 down NNTVIDELPFKS(ph)PITK ddPTM_PC-9_Lapatinib_30min_R1 1 NNTVIDELPFKSPITK 16 1 Q9UQC2-2;Q9UQC2 Q9UQC2-2 GAB2 GRB2-associated-binding protein 2 1 NNTVIDELPFKS(0.992)PIT(0.008)K 62.19 0.018137 4312600.0 6320.7 7329.3 8547.1 6884.1 22350.0 31675.0 34164.0 30833.0 39561.0 34071.0 True False 6230.56565892558 7312.32945616085 7844.390430760109 7390.379678684393 21035.41694179063 30320.33408803139 35932.84475426417 32265.61374140045 35105.22358420148 39960.1269532462 0.1559195661769396 0.1829906462688759 0.19630544317184312 0.18494384883539586 0.5264101629707609 0.7587647087184314 0.8992174823745182 0.807445226066263 0.8785063076820298 1.0 15.286273546126422 -6.56078999190295 1.6666097382689573 0.8823977445453896 0.16709006921300143 0.9771501887240233 0.04991372531290454 0.048091178320989934 0.27262277653882805 0.019120368936261067 0.020343117047300626 2.7492232502827157e-07 6.56078999190295 -0.7153076753323881 down NNTVTPGGKPNK ddPTM_PC-9_Lapatinib_30min_R1 1 NNTVTPGGKPNK 12 1 C9K025;P18077 C9K025 RPL35A 60S ribosomal protein L35a 0 99.5 0.0043119 10497000.0 46795.0 45720.0 51689.0 37228.0 45518.0 32697.0 51245.0 46898.0 44029.0 42343.0 False True 46127.69471884798 45614.13814902845 47439.329945310026 39965.871308967406 42840.72073183117 31298.625530429745 53898.215356289256 49077.052289566316 39069.990374075656 49661.93113149904 0.9288340921883845 0.9184930410427958 0.9552453733564282 0.8047587034652842 0.8626470971979302 0.6302337588837335 1.0853024465273617 0.9882227930205929 0.7867191122838709 1.0 15.599852742144913 -9.620875921647851 8.898040084394855 0.9999994954972925 0.8860677623020601 0.07871290654926355 0.11843854584400959 155084192.11092195 0.0 0.1165141213745049 0.029128530343626224 2.39399962671075e-10 9.620875921647851 -0.11393173319523242 NNVGERDDDVPADMVAEES(ph)GPGAQNSPYQLR ddPTM_PC-9_AZD4547_30min_R2 2 NNVGERDDDVPADMVAEESGPGAQNSPYQLR 31 1 Q86XK2-4;Q86XK2;Q86XK2-5 Q86XK2-4 FBXO11 F-box only protein 11 1 NNVGERDDDVPADMVAEES(0.521)GPGAQNS(0.467)PY(0.012)QLR;NNVGERDDDVPADMVAEES(0.79)GPGAQNS(0.112)PY(0.098)QLR 96.55 3.0295e-12 7371400.0 12350.6 12304.2 18879.9 24765.7 20928.8 19273.0 16874.2 17989.1 15594.1 22752.3 True False 16277.83389156122 16281.292028254862 18629.54019009248 19056.350491250767 18023.197377384407 18067.85626326677 18375.97111034312 15209.297943394049 16418.372290013875 21955.74890226113 0.7413927880130218 0.7415502928519154 0.8485039737439293 0.8679435429910676 0.8208873884291997 0.8229214290843907 0.8369548764720413 0.6927250813033168 0.7477937720595363 1.0 14.422311124633415 -5.247008093604006 23.19064541498725 0.8198079451661585 0.7414714897849504 0.16937345182115593 0.07566416608193643 601.0950840248062 965928.3128546689 0.019259617459407068 0.050330960785484664 5.662287365811867e-06 5.247008093604006 -0.07833645538120815 NNVGERDDDVPADMVAEESGPGAQNS(ph)PYQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NNVGERDDDVPADMVAEESGPGAQNSPYQLR 31 1 Q86XK2-4;Q86XK2;Q86XK2-5 Q86XK2-4 FBXO11 F-box only protein 11 1 NNVGERDDDVPADMVAEES(0.026)GPGAQNS(0.974)PYQLR 109.99 2.6378e-08 0.0 4835.5 4474.8 1743.7 4628.5 6687.1 8337.9 3958.2 5164.2 6292.2 4839.7 True False 5654.054644521624 4919.028571077057 1785.276421019075 4369.180150799466 5376.810758749007 7900.645845965928 3583.250641113633 5028.645221922189 6384.211521327112 5717.09929895588 0.9889726151081949 0.8604063553654603 0.31226961920096824 0.7642302367561491 0.9404788123464953 1.3819325907823277 0.6267602596596574 0.879579828680005 1.1166871847919568 1.0 12.481067632982922 -6.2526130148523915 4.653376362562067 0.9879464434278676 0.7075478116166333 0.21948213866753763 0.23994219311176063 0.31537106527826997 19.058641087788875 0.0767452324411158 0.09478943181496553 5.58968050447256e-07 6.2526130148523915 -0.28039863181123437 NNYYSSRFS(ph)PDSQYIDNR ddPTM_PC-9_AZD4547_30min_R2 2 NNYYSSRFSPDSQYIDNR 18 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 NNY(0.002)Y(0.007)S(0.016)S(0.016)RFS(0.853)PDS(0.023)QY(0.082)IDNR;NNY(0.002)Y(0.002)S(0.003)S(0.005)RFS(0.663)PDS(0.261)QY(0.065)IDNR 67.668 0.0060146999999999996 19544100.0 39940.0 28372.0 47745.0 88527.0 69866.0 54799.0 32630.0 60517.0 29692.3 53200.0 True False 52640.089196391695 37542.69415530037 47111.87010397119 68118.46787851569 60166.31187494455 51372.4098672109 35534.006787314116 51165.48819231524 31261.77435996816 51337.484192819735 1.0253733704339596 0.731292051910702 0.917689498126214 1.3268758481165115 1.1719762434981114 1.000680315269443 0.6921649423616291 0.9966496994699139 0.6089463644644386 1.0 15.64772497753768 -7.109554082835608 7.275510165007286 0.8250492996433746 1.0331536486730013 0.23239720099433214 0.1829050982564518 0.4411204103400127 26.028133102745226 0.07438419424731484 0.057603669669649527 7.770445471535991e-08 7.109554082835608 0.2081043490296267 NNYYSSRFSPDS(ph)QYIDNR ddPTM_PC-9_Lapatinib_30min_R1 1 NNYYSSRFSPDSQYIDNR 18 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 NNYYSSRFS(0.034)PDS(0.541)QY(0.425)IDNR 62.236999999999995 0.010048999999999999 6521600.0 54264.0 25883.0 43419.0 39221.0 32485.0 32560.0 25279.0 25564.0 38652.0 26853.0 True False 53490.18540920117 25823.069503746778 39849.257422186856 42105.44317742056 30574.296167967306 31167.48470106714 26587.82292890305 26751.796765970255 34298.60473639582 31494.505270626647 1.6983973854985046 0.8199230082153621 1.265276500766382 1.3369139415150681 0.9707819159325682 0.9896165833770215 0.8442051304009587 0.8494115572255178 1.0890345614790278 1.0 14.942812528470132 -6.3200982581039975 6.800892925769114 0.944208852231083 1.2458756447621664 0.3571182457313965 0.2099019247804156 0.2923893877542501 28.3978287847108 0.06309282846961652 0.07189330993625749 4.785218156403044e-07 6.3200982581039975 0.3016667925310834 NPDDITNEEYGEFYK ddPTM_PC-9_AZD4547_30min_R2 4 NPDDITNEEYGEFYK 15 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ;;; 261.45 4.4681e-50 77258000.0 168890.0 148296.0 202275.0 278848.0 237469.0 227697.0 182711.0 227974.0 189423.0 212864.0 False True 222593.50686976957 196229.78191366215 199592.70133586298 214563.90175865425 204500.52836331204 213459.07059498056 198971.92504189213 192745.85662136035 199435.51306528097 205411.69615075953 1.0836457272929563 0.9552999444084312 0.9716715507250095 1.0445554259051422 0.9955641874122945 1.0391768073338665 0.9686494429015328 0.9383392486078143 0.9709063154753739 1.0 17.648158805549038 -7.379656836438293 7.2803214621412655 0.9636447889524193 1.0106887077077527 0.25145839720775 0.037577844597253086 0.3718325648571864 20.886222034192176 0.015592550782126634 0.010457801144530035 4.171989085308933e-08 7.379656836438293 0.047043918755333314 NPDDITNEEYGEFYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NPDDITNEEYGEFYK 15 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ;;; 238.03 2.0012e-31 54569000.0 106234.0 105674.0 117877.0 121191.0 129274.0 111159.0 126430.0 125124.0 110379.0 84976.0 False True 124217.31798285806 116164.61634486388 120687.63473101186 114401.06117652346 103943.68770117383 105329.62635576418 114453.6351260665 121839.62757983683 111993.08405844761 100381.47613035415 1.237452593559702 1.1572316011174606 1.2022898983303292 1.139663069189814 1.035486742257046 1.0492934594723873 1.1401868107362598 1.2137660480467272 1.1156748075014833 1.0 16.615133540931623 -5.928802966313686 4.482552533966499 1.1020434764957647 1.1939121145683855 0.385866941609076 0.05930591533311343 0.26866667822266965 10.443844216020803 0.018243538625864326 0.02752248763516669 1.1781403590533287e-06 5.928802966313686 0.0918686380726208 NPDDITNEEYGEFYK ddPTM_PC-9_Lapatinib_30min_R1 4 NPDDITNEEYGEFYK 15 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ;;; 167.03 0.00051823 156655000.0 196605.0 147414.0 195358.0 160700.0 194274.0 161310.0 174573.0 156336.0 171577.0 140075.0 False True 193801.37664705887 147072.67194008952 179296.419343688 172518.41407948505 182847.18527737964 154411.14733197598 183611.5357477506 163599.9412926271 152252.19147409147 164286.7771117944 1.1796529218853706 0.8952191681258014 1.0913624486143507 1.050105292175092 1.1129756666475672 0.9398878597934988 1.1176282046290678 0.9958192872777588 0.926746474370767 1.0 17.325856841742905 -7.991763471659844 24.63021005793244 0.9626764357806338 1.0486961742891319 0.17722464310530983 0.08119975096084213 246.41137695794947 736859.0316435402 0.04140483697123487 0.019835142311918796 1.0191462911430387e-08 7.991763471659844 0.08601973850849809 NPDDITQEEYGEFYK ddPTM_PC-9_AZD4547_30min_R2 3 NPDDITQEEYGEFYK 15 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 ;; 184.76 1.0419e-29 16947100.0 78319.0 72276.0 97359.0 121707.0 100522.0 108571.0 85618.0 113634.0 87356.0 90427.0 False True 103222.81286360031 95637.80356578648 96067.95604675944 93649.33150440555 86566.25543602293 101782.03820677286 93237.83613595643 96074.47634954713 91973.45981919137 87261.17825383651 1.182917935892781 1.0959948682744458 1.1009243511164226 1.0732072770320193 0.9920362888546829 1.1664068746664893 1.0684916018980886 1.100999072807307 1.0540020391616438 1.0 16.413052333546815 -1.5228787452873815 0.011574169239429668 6.744246821068671e-11 2.3360022037966353 0.33149348849378024 0.04771904596890927 12643.043222027864 11.35024561744263 964.3458471290854 1357.51454031445 0.02999999999951342 1.5228787452873815 2.3360022037291928 NPDDITQEEYGEFYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NPDDITQEEYGEFYK 15 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 ;;; 203.85 2.6461999999999997e-50 18360200.0 87671.0 93130.0 101740.0 120493.0 130384.0 115527.0 117435.0 102671.0 109357.0 101196.0 False True 102511.96871882005 102375.33092527185 104165.86745109847 113742.16785357674 104836.19116937554 109468.56074633976 106310.706644227 99975.99503891646 110956.13924188193 119542.03373290456 0.8575391058501216 0.856396095401985 0.871374396087644 0.9514826233232188 0.8769818271923782 0.9157327956367868 0.8893165301316471 0.836325030761105 0.9281767741194175 1.0 16.86715846666145 -14.522878742310231 0.3108046546753311 2.0095848171969086 0.881533521628577 0.5190791468185866 0.03317599657064982 253.5081516336308 2.292628229526841 167.60094550946278 0.032138060493235004 3.000000020516766e-15 14.522878742310231 -1.1280512955683317 NPDDITQEEYGEFYK ddPTM_PC-9_Lapatinib_30min_R1 3 NPDDITQEEYGEFYK 15 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 ;; 218.68 2.7710999999999997e-17 74517000.0 169721.0 142648.0 177133.0 152426.0 155713.0 153861.0 156353.0 146445.0 142214.0 140526.0 False True 167300.7474169805 142317.70732026667 162569.8084931532 163635.91651823022 146554.26748353668 147280.72369750895 164448.19329889564 153249.36932375687 126196.36174018923 164815.73186087483 1.01507753858232 0.863495891523272 0.9863731250508447 0.9928416096611425 0.8892007202761862 0.893608407611431 0.9977700031554667 0.9298224604743349 0.7656815300053686 1.0 17.33049443051644 -6.269727159063852 24.808661525661197 0.9124725125240711 0.9588023940961677 0.10839455705538781 0.07200819639236047 1505.9415381893787 4507882.215323384 0.022159390992344433 0.025570731166789207 5.373692869439797e-07 6.269727159063852 0.04632988157209661 NPDELAEALDER ddPTM_PC-9_Lapatinib_30min_R1 1 NPDELAEALDER 12 0 K7EM11;O14908-2;O14908 K7EM11 GIPC1 PDZ domain-containing protein GIPC1 0 113.61 0.0026834 0.0 2728.0 1306.1 2244.1 2463.0 2694.5 2269.1 3113.6 2533.2 3171.0 1999.1 False True 2689.098219746071 1303.075805696545 2059.598760476508 2644.1372363271407 2536.014807590823 2172.0558825304493 3274.806973038194 2650.901719901261 2813.84858788966 2344.641771366689 1.1469121861539635 0.5557675469276415 0.8784279055456603 1.127736129509403 1.0816214393862744 0.9263913613824086 1.3967195385797944 1.1306212114254253 1.2001187653709122 1.0 11.19515180051497 -5.720072010520943 4.679417039775478 1.1312134279467105 0.8220225312716712 0.3125899629011576 0.1772138996853911 0.2077029860968011 10.071020905856525 0.04783959086374394 0.08242461787366752 1.9051447990427976e-06 5.720072010520943 -0.3091908966750393 NPDTQWITKPVHK ddPTM_PC-9_Lapatinib_30min_R1 1 NPDTQWITKPVHK 13 1 P61313;A0A2R8YEM3;E7EQV9;E7ENU7 P61313 RPL15 60S ribosomal protein L15;Ribosomal protein L15 0 80.318 0.0058076000000000004 4472300.0 39287.0 35136.0 39729.0 39837.0 36693.0 35868.0 32953.0 29106.0 40892.0 33832.0 False True 38726.76017564658 35054.64475074941 36462.63497837492 42766.745872336294 34534.78988121358 34334.00925239177 34659.14509973268 30458.371016676985 36286.31234815011 39679.81612169367 0.9759813416694227 0.8834376813451109 0.9189214704661934 1.0777959691439936 0.8703364394456654 0.8652764203113519 0.8734704060481748 0.7676036331233109 0.9144778352012506 1.0 15.276117719766795 -6.452464285001963 24.999967823914677 0.8688410896193958 0.9574314244386063 0.22623981338543186 0.07166473767186846 221.12270995945096 78506.83958916004 0.02188542579934396 0.024815733805481213 3.5280579905363635e-07 6.452464285001963 0.08859033481921053 NPDVDTSFLPDRDREEEENRLR ddPTM_PC-9_Lapatinib_30min_R1 1 NPDVDTSFLPDRDREEEENRLR 22 3 B0S8I6;Q9Y247;Q14320 B0S8I6 FAM50A;FAM50B Protein FAM50B;Protein FAM50A 0 45.413000000000004 0.020913 12537000.0 13974.0 5531.1 5368.9 6415.0 3332.6 6178.5 4103.7 3326.5 5439.4 3837.2 False True 13774.72819748225 5518.293077779774 4927.489766553326 6886.780499812671 3136.58302014369 5914.259957786955 4316.169506441687 3481.0613339852935 4826.757492578692 4500.454907252394 3.0607412986817284 1.2261633971461758 1.0948870432215139 1.530240973799062 0.6969479940992518 1.3141471428268823 0.959051828179917 0.7734909927384522 1.0725043561264147 1.0 12.135855121497036 -4.758074802087011 4.312635804239603 1.0618805733306937 3.255044485809497 0.8741132017962211 0.22697665005063106 0.07251585980155825 2.775710097799814 0.05652920581972777 0.5042695549787359 1.745521481601191e-05 4.758074802087011 2.193163912478803 up NPEAALS(ph)PTFR ddPTM_PC-9_AZD4547_30min_R2 1 NPEAALSPTFR 11 0 B4E349;F5H6D8;B4DTN4;Q86U44 B4E349 METTL3 N6-adenosine-methyltransferase 70 kDa subunit 1 NPEAALS(0.995)PT(0.005)FR 84.352 0.012055 12482000.0 19794.0 18835.0 22855.0 33138.0 36716.0 31138.0 19765.0 33342.0 17910.0 21482.0 True False 26088.080259223265 24923.045411500178 22551.927766808283 25498.54607699633 31618.617164292533 29190.93593761223 21524.046710121474 28189.760022938568 18856.686036010327 20729.921718611917 1.25847461526112 1.2022739762265264 1.0878925677061537 1.2300358111870247 1.5252646678305801 1.4081546632857649 1.0383081519693618 1.359858488883197 0.9096361429614206 1.0 14.33942704802844 -8.267633014430952 24.97659635228031 0.954818026050486 1.2607572900925075 0.446390886393621 0.13759693775384021 527.2002656279228 2125966.4351690216 0.12898555913722415 0.03660204266152049 5.399667100272785e-09 8.267633014430952 0.30593926404202143 NPEAALS(ph)PTFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NPEAALSPTFR 11 0 B4E349;F5H6D8;B4DTN4;Q86U44 B4E349 METTL3 N6-adenosine-methyltransferase 70 kDa subunit 1 NPEAALS(0.929)PT(0.071)FR 103.97 0.0027403 6785500.0 12091.0 7178.3 15929.0 14408.0 17415.0 15055.0 17388.0 14551.0 14715.0 11473.0 True False 14137.767491864535 7890.914184268004 16308.807771068896 13600.766471366254 14002.65576462353 14265.489297187196 15740.88276178159 14169.0516680589 14930.179036955025 13552.964079781965 1.0431494843961822 0.58222792725021 1.2033388176242599 1.0035270802241407 1.0331803199797753 1.052573386398047 1.1614346993853188 1.0454577747458214 1.1016172513308407 1.0 13.72632078799586 -5.275717628185774 24.999179895366876 1.0749843288757859 0.8126886719099725 0.43229282586011564 0.1203048983918236 581.508727973861 1018138.9615622559 0.028835556880638245 0.060478563682138636 5.3000793516626e-06 5.275717628185774 -0.26229565696581336 NPEAALS(ph)PTFR ddPTM_PC-9_Lapatinib_30min_R1 1 NPEAALSPTFR 11 0 B4E349;F5H6D8;B4DTN4;Q86U44 B4E349 METTL3 N6-adenosine-methyltransferase 70 kDa subunit 1 NPEAALS(0.969)PT(0.031)FR 84.29700000000001 0.012085 3524200.0 12551.0 11376.0 12337.0 11238.0 12958.0 11952.0 10946.0 13399.0 12255.0 10206.0 True False 12372.020438428492 11349.659570939364 11322.699482197171 12064.48000886903 12195.835916408198 11440.840821472808 11512.73032081066 14021.566455454371 10874.712849128926 11970.093501359832 1.0335775937776093 0.9481679963193282 0.9459157090887289 1.007885193837331 1.018858868146913 0.9557854180648715 0.9617911772788397 1.1713832021330064 0.9084902175487211 1.0 13.547146801122535 NPEAALSPT(ph)FR ddPTM_PC-9_AZD4547_30min_R2 1 NPEAALSPTFR 11 0 B4E349;F5H6D8;B4DTN4;Q86U44 B4E349 METTL3 N6-adenosine-methyltransferase 70 kDa subunit 1 NPEAALS(0.017)PT(0.983)FR 107.39 0.0056627 10494000.0 16480.0 19880.0 22547.0 34686.0 30805.0 23271.0 21929.0 24393.0 21058.0 18808.0 True False 21720.297194705425 26305.821225411382 22248.01204805192 26689.678593357934 26528.25748300555 21815.860691251022 23880.63851789798 20623.622345376418 22171.08288924094 18149.537644709668 1.1967410751665393 1.4493934633689776 1.225817014382011 1.4705431684171633 1.46164921676328 1.2020064157177048 1.3157711775020806 1.1363166791958423 1.2215783852600508 1.0 14.147645175914787 -8.224182989901012 0.6873847969673452 1.0125822648776808 1.3568106450704667 0.49956382416643674 0.1040264193028399 0.5400559251229768 0.5730448564393771 0.09843297493554684 0.04239723384442192 5.9678377886444e-09 8.224182989901012 0.3442283801927859 NPEAALSPT(ph)FR ddPTM_PC-9_Lapatinib_30min_R1 2 NPEAALSPTFR 11 0 B4E349;F5H6D8;B4DTN4;Q86U44 B4E349 METTL3 N6-adenosine-methyltransferase 70 kDa subunit 1 NPEAALS(0.231)PT(0.769)FR;NPEAALS(0.136)PT(0.864)FR 123.95 0.0013112 19090300.0 43881.0 50738.0 65649.0 41709.0 53700.0 56023.0 39276.0 50939.0 55487.0 36143.0 True False 43255.24889321013 50620.5192783334 60251.59263246837 44776.41899714522 50541.4715782621 53627.02688599152 41309.51910105604 53305.811901962086 49237.46975598667 42390.26939247975 1.0204051428105299 1.194154224632357 1.4213543224888612 1.0562900316243045 1.1922894641294357 1.2650786997712553 0.9745047552914244 1.257501135659657 1.161527644472145 1.0 15.371445514377458 NPEEFKT(ph)S(ph)VS(ph)LAVSR ddPTM_PC-9_Lapatinib_30min_R1 1 NPEEFKTSVSLAVSR 15 1 E9PNC4;A0A0G2JRS3;A0A0G2JRF9;A0A0G2JQA4;E9PR62;A0A0G2JQM1;A0A0G2JS82;O94973-3;O94973;O94973-2 E9PNC4 AP2A2 AP-2 complex subunit alpha-2 3 NPEEFKT(0.982)S(0.978)VS(0.978)LAVS(0.062)R 49.928999999999995 0.031871 5661400.0 2840.4 5967.7 7392.5 5252.5 3189.8 2345.2 6955.6 3402.9 7162.4 2907.2 True False 2799.8953751344343 5953.882157304398 6784.717185875222 5638.78637182635 3002.182235388089 2244.901262928215 7315.726933987817 3561.0111568972097 6355.695088584333 3409.705646399497 0.8211545703632817 1.7461572272643073 1.9898248967735948 1.6537457940924216 0.8804813513912161 0.6583856484206297 2.1455596736665266 1.0443749479247526 1.8640011038183528 1.0 11.735431484084746 NPLPPILGS(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 1 NPLPPILGSPTK 12 0 O75385 O75385 ULK1 Serine/threonine-protein kinase ULK1 1 NPLPPILGS(0.927)PT(0.073)K 108.66 0.0014053 30889000.0 74186.0 62059.0 69106.0 110710.0 107610.0 76229.0 80802.0 74026.0 71688.0 82301.0 True False 97775.60483534086 82118.35812011105 68189.60928694169 85187.51995244922 92670.20898380886 71462.38857949257 87993.22146578478 62586.98264825301 75477.28132604739 79419.66704047473 1.2311258467693067 1.0339801359058958 0.8585985289033023 1.0726249948773396 1.166842073721881 0.8998072044682978 1.1079525354965376 0.7880539541466063 0.9503600825672289 1.0 16.277208692060498 -7.748692013143246 24.999793264837766 0.9019052305659745 1.044024879948789 0.22983525890576428 0.11628015336833093 321.0354720570332 629608.9792717829 0.055029030426418844 0.03150439548894302 1.78364321807108e-08 7.748692013143246 0.14211964938281452 NPLPPILGS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NPLPPILGSPTK 12 0 O75385 O75385 ULK1 Serine/threonine-protein kinase ULK1 1 NPLPPILGS(0.906)PT(0.094)K;NPLPPILGS(0.643)PT(0.357)K 109.1 0.0013524000000000001 40541000.0 91352.0 77817.0 67856.0 107511.0 121692.0 117591.0 139227.0 117942.0 106116.0 113455.0 True False 106816.08931575605 85542.15748536344 69473.94438531314 101487.50722536488 97847.32617333143 111424.32095287534 126038.41064380987 114846.14746987866 107667.7457482516 134023.49339071414 0.796995262646667 0.638262406994461 0.5183713886846548 0.7572366952822354 0.7300759269725976 0.8313790226915202 0.9404202759912724 0.8569105651877883 0.8033497935647109 1.0 17.032126391742466 -6.633618313779294 1.5623717132820778 0.8900787090673049 0.6591177854703394 0.5933627731355225 0.08424646101706441 0.27739041152843597 1.3989211628925944 0.035835221547379496 0.03609478627962544 2.324779065744368e-07 6.633618313779294 -0.23096092359696552 NPLPPILGS(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 1 NPLPPILGSPTK 12 0 O75385 O75385 ULK1 Serine/threonine-protein kinase ULK1 1 NPLPPILGS(0.903)PT(0.097)K 78.985 0.015877000000000002 21609000.0 94265.0 90060.0 86375.0 73859.0 95575.0 106140.0 118400.0 110270.0 109390.0 83127.0 True False 92920.76381391617 89851.47160326969 79273.58091714203 79290.83724640113 89953.46640767975 101600.63962442467 124530.17266435083 115393.54676042647 97069.34627223268 97495.3911902352 0.9530785268875642 0.9215971186571218 0.8131008035288728 0.8132777998878642 0.9226432686665211 1.0421071025416906 1.2772929175838144 1.1835795041354107 0.9956301019689104 1.0 16.57304640083069 -6.823211083014197 3.129957435746955 1.1320316339661882 0.8750606876986705 0.6025521756737633 0.0882406884739232 0.16240907701682833 3.2261454790145474 0.0337210451359176 0.030276201744333053 1.502411561592728e-07 6.823211083014197 -0.2569709462675177 NPLPPILGSPT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 NPLPPILGSPTK 12 0 O75385 O75385 ULK1 Serine/threonine-protein kinase ULK1 1 NPLPPILGS(0.095)PT(0.905)K 114.21 0.0019055 23475000.0 102950.0 80789.0 64175.0 74721.0 96628.0 100350.0 109720.0 100310.0 104930.0 65529.0 True False 101481.91412128224 80601.93803416117 58898.77922266383 80216.23160194886 90944.5310179573 96058.26442727546 115400.76473591675 104970.76879965891 93111.67843811479 76855.60033809599 1.3204231529628612 1.0487451490793727 0.7663563743378727 1.043726563179119 1.1833169036203295 1.2498538038178728 1.5015270745171005 1.3658180840157554 1.2115145549381772 1.0 16.229862770052595 -6.507302657533404 2.5003789379265955 1.3036337837422276 1.0264303117536393 0.25123511859311887 0.17341417783686716 0.34720361603412425 4.351782362186024 0.0626742188003907 0.06781789922394725 3.1095485538520226e-07 6.507302657533404 -0.2772034719885883 NPPGFAFVEFEDPR ddPTM_PC-9_Lapatinib_30min_R1 3 NPPGFAFVEFEDPR 14 0 A0A087X2D0;P84103-2;P84103;Q16629-4;Q16629;A0A0B4J1Z1;C9JAB2;Q16629-3;Q16629-2 A0A087X2D0;Q16629-4 SRSF3;SRSF7 Serine/arginine-rich splicing factor 3;Serine/arginine-rich splicing factor 7 0 ;; 185.25 2.7519000000000002e-05 26000600.0 15668.6 19163.1 18101.5 18312.0 14510.6 12004.2 15373.4 14520.6 21724.1 12502.599999999999 False True 15445.162890730664 19118.729019327347 16613.26454381066 19658.72556704125 13657.115036937243 11490.80834915695 16169.359429376094 15195.28008605648 19277.303093085404 14663.657751332674 1.053295375045627 1.303817188285766 1.132955012012661 1.3406426895945938 0.93135800552192 0.7836249688869501 1.1026825437129817 1.0362544150810866 1.3146312754969631 1.0 13.839957398539257 -6.269289413276139 24.788443904152633 1.0214107789567295 1.2092073585437015 0.264682100688752 0.14637724167832775 738.8868419160477 2333215.160218841 0.046405433068502096 0.05357729251651316 5.379111997282928e-07 6.269289413276139 0.18779657958697205 NPPGFAFVEFEDPRDAADAVR ddPTM_PC-9_AZD4547_30min_R2 2 NPPGFAFVEFEDPRDAADAVR 21 1 A0A087X2D0;P84103-2;P84103 A0A087X2D0 SRSF3 Serine/arginine-rich splicing factor 3 0 ; 115.91 4.2593e-06 8012800.0 4745.1 7215.5 5973.5 8905.9 7134.599999999999 7635.0 2324.8199999999997 6426.9 4772.2 5447.8 False True 6253.943095788636 9547.769268207034 5894.287486984434 6852.782349783381 6144.083942160403 7157.582243036464 2531.7244762268965 5433.770280469795 5024.448749360608 5257.0741801812665 1.1896242817659837 1.8161754886779669 1.1212106363660244 1.3035354105555141 1.1687268871577066 1.3615144085316422 0.481584316571238 1.0336111103310388 0.9557500193362999 1.0 12.360044376928656 -7.22504262379013 24.864855200030284 0.8705372050892554 1.331455080417474 0.4885369616334171 0.23007291960778292 463.4765817563778 316629.63080509036 0.08683771236020951 0.0672619823039746 5.95603685194001e-08 7.22504262379013 0.4609178753282187 NPPGFAFVEFEDPRDAADAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NPPGFAFVEFEDPRDAADAVR 21 1 A0A087X2D0;P84103-2;P84103 A0A087X2D0 SRSF3 Serine/arginine-rich splicing factor 3 0 ; 70.615 0.0034715 6053200.0 878.44 1811.0 0.0 1719.87 3023.8 3119.3 2181.68 2230.6000000000004 3283.1 2522.8999999999996 False True 1027.1425420191458 1990.7841115179567 0.0 1623.5112597937714 2431.3080965299246 2955.718416786183 1975.0154764046263 2172.0491135160605 3331.109126485019 2980.2817987345893 0.3446461144900005 0.6679851926630671 0.0 0.5447509227090891 0.8157980555940194 0.991758033767533 0.6626942047034635 0.7288066230644029 1.1177161595589347 1.0 11.541233034952137 -6.164935467441051 3.485418478888966 0.8690793481568796 0.36006644200668236 0.6120298665812092 0.1974672978218415 0.175540358812709 4.011810521111831 0.06007168523076374 0.07931866728638477 6.840132784319761e-07 6.164935467441051 -0.5090129061501972 NPPGFAFVEFEDPRDAADAVR ddPTM_PC-9_Lapatinib_30min_R1 2 NPPGFAFVEFEDPRDAADAVR 21 1 A0A087X2D0;P84103-2;P84103 A0A087X2D0 SRSF3 Serine/arginine-rich splicing factor 3 0 ; 57.41 0.018650999999999997 7606700.0 8760.7 3565.0 5697.099999999999 3606.8999999999996 6007.9 5696.7 3815.0 3344.8 5582.4 2946.6000000000004 False True 8635.770811484388 3556.7454615329475 5228.706429441967 3872.163458265678 5654.52713398586 5453.065420656302 4012.5220330616357 3500.2116187927304 4953.651326721933 3455.915883902298 2.4988370960386863 1.0291759351262904 1.512972712616459 1.1204449379981343 1.636187720981498 1.5778929823080339 1.1610589400488642 1.0128173648834344 1.433383072139026 1.0 11.754852387767096 -4.753598014595441 24.99208399651671 1.2960367286569794 2.4988392754379816 0.709637010125793 0.23434770039448835 158.82141313508228 506156.4666199104 0.058070866435173125 0.6154840134904674 1.763607696323155e-05 4.753598014595441 1.2028025467810022 NPPGFAFVEFEDPRDAEDAVR ddPTM_PC-9_AZD4547_30min_R2 2 NPPGFAFVEFEDPRDAEDAVR 21 1 Q16629-4;Q16629;A0A0B4J1Z1;C9JAB2;Q16629-3;Q16629-2 Q16629-4 SRSF7 Serine/arginine-rich splicing factor 7 0 ; 59.342 0.015030000000000002 5759700.0 756.61 1650.02 713.46 2201.82 2393.17 1533.04 826.65 1082.5 685.66 786.11 False True 997.196241534349 2183.356697100267 703.9990542335173 1694.2244167798938 2060.9196546211438 1437.1787664524725 900.2202485667547 915.2244983753534 721.9025877973671 758.5885281732621 1.3145416843247975 2.8781831203774635 0.9280380971866259 2.2333905059963306 2.7167819945603346 1.8945432379702687 1.1867042739685931 1.2064834417932504 0.9516392101733498 1.0 9.567173744279685 -7.254904319662238 3.930768818016969 1.0873333827716334 2.0386168578937514 0.3986144294624706 0.5482627050430261 0.23068643371521882 8.320734524037455 0.22686811000935858 0.16029205540660849 5.5602674320759234e-08 7.254904319662238 0.951283475122118 NPPGFAFVEFEDPRDAEDAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NPPGFAFVEFEDPRDAEDAVR 21 1 Q16629-4;Q16629;A0A0B4J1Z1;C9JAB2;Q16629-3;Q16629-2 Q16629-4 SRSF7 Serine/arginine-rich splicing factor 7 0 ; 93.115 0.00052002 4975600.0 2177.9 1501.7399999999998 3181.49 2120.56 2470.86 1536.85 1939.54 2177.0 1152.4 1308.56 False True 2546.5754545142477 1650.8228225460928 3257.3487874680154 2001.7518981482788 1986.7127202169206 1456.2548805301988 1755.8127301464149 2119.856056722166 1169.251669873393 1545.7915694447386 1.6474248565277136 1.0679465816591833 2.107236739968819 1.2949688287324048 1.2852397176228387 0.9420771269009429 1.1358664161799754 1.3713725049513865 0.7564096563765049 1.0 10.594130087753788 -6.2572013843103855 2.463977871285561 1.0790924564342672 1.5590270294218833 0.3946867001525314 0.28657469611528563 0.32204931053577396 3.8593108154386955 0.09161209096336442 0.11667081661541977 5.530935777558939e-07 6.2572013843103855 0.4799345729876161 NPPGFAFVEFEDPRDAEDAVR ddPTM_PC-9_Lapatinib_30min_R1 2 NPPGFAFVEFEDPRDAEDAVR 21 1 Q16629-4;Q16629;A0A0B4J1Z1;C9JAB2;Q16629-3;Q16629-2 Q16629-4 SRSF7 Serine/arginine-rich splicing factor 7 0 ; 135.79 9.246200000000001e-05 6942400.0 3106.3799999999997 2595.7 2846.92 2190.8 2272.18 2488.1 1716.35 1174.19 2079.44 1247.7 False True 3062.0824515596773 2589.6898161293334 2612.857227029 2351.9187402945577 2138.534839677756 2381.6897630443846 1805.2142048349513 1228.7471539913402 1845.2315697260408 1463.3632825442537 2.0924964348127113 1.769683473010755 1.7855150926611993 1.607200869633295 1.4613834207727459 1.6275451157305907 1.233606327539081 0.839673352918216 1.260952486465191 1.0 10.515072250218143 -6.5044514244806955 0.4462303989419712 0.9465939244163816 2.0831363370228817 0.824592748261605 0.15321626761646487 0.564135147155742 0.2228106497003471 0.14775853121135435 0.2802102751103135 3.130030543606501e-07 6.5044514244806955 1.1365424126065 up NPPS(ph)PRPSQLPVLDR ddPTM_PC-9_AZD4547_30min_R2 1 NPPSPRPSQLPVLDR 15 1 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 NPPS(1)PRPSQLPVLDR 72.932 0.0087914 39836000.0 36525.0 41827.0 57960.0 38861.0 50262.0 41179.0 47381.0 71810.0 55231.0 44743.0 True False 48139.19023280436 55346.75977843471 57191.41252960875 29902.196846464944 43283.98888527268 38604.07062030105 51597.817210840636 60713.414529638845 58150.39790367872 43176.56118870929 1.1149380336800143 1.2818704930328713 1.324593968464639 0.692556239385836 1.0024881021926193 0.8940978521095387 1.195042305136925 1.4061660507024227 1.346804754772483 1.0 15.397960723568579 -7.515048485834487 23.873502736825966 1.286012118443044 1.0550951121924634 0.17274883369307004 0.19689986692066166 338.2045688342731 1031161.2771812963 0.09389944159387653 0.057409630829494414 3.054580072429458e-08 7.515048485834487 -0.23091700625058054 NPPS(ph)PRPSQLPVLDR ddPTM_PC-9_Lapatinib_30min_R1 1 NPPSPRPSQLPVLDR 15 1 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 NPPS(0.996)PRPS(0.004)QLPVLDR 55.688 0.032764 31557000.0 27955.0 33576.0 35518.0 32507.0 39257.0 40753.0 38642.0 40101.0 37434.0 35336.0 True False 27556.356573680867 33498.2568349033 32597.84714344488 34897.673220173085 36947.980442231565 39010.089189882965 40642.693683241894 41964.23885589789 33217.78872250445 41443.780517739644 0.6649093357177107 0.8082818800896957 0.7865558290342664 0.8420485000212624 0.8915205123822212 0.9412772846141544 0.9806705173975416 1.0125581771657022 0.8015144445687301 1.0 15.338867991778146 -5.162389524203903 0.5366376274021364 0.9597905639974367 0.5821938884570992 0.6792238006994735 0.06026840642281714 1.7251880941652764 0.507391890107441 0.037292268589564186 0.3879365288013472 6.880349123164187e-06 5.162389524203903 -0.3775966755403375 NPQMPQYSSPQPGS(ph)ALSPR ddPTM_PC-9_Lapatinib_30min_R1 2 NPQMPQYSSPQPGSALSPR 19 0 O14497-2;O14497;H0Y488;A0A1B0GTU5;O14497-3;A0A087WUV6 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 NPQMPQYSSPQPGS(0.91)ALS(0.09)PR;NPQMPQYSS(0.005)PQPGS(0.595)ALS(0.4)PR 240.82 3.9260999999999994e-44 15540000.0 35935.0 24446.0 28927.0 24130.0 29126.0 31915.0 27892.0 27800.0 26375.0 23314.0 True False 35422.56031032807 24389.396788957776 26548.733721449116 25904.600695320307 27412.865943919194 30550.06984749869 29336.111283395858 29091.689488889584 23404.369758937195 27343.79383604772 1.2954515574071508 0.8919536526348761 0.9709235624227658 0.9473667352322521 1.0025260616096519 1.1172579061514167 1.07286177840917 1.0639229385403568 0.8559298647169755 1.0 14.73892580423199 -8.246141443180955 24.737645994802893 0.9279649200916343 1.0363227447400225 0.15084837102438942 0.10970328064721235 1221.2006643163013 1974760.743360808 0.07363234300243827 0.027593815512589027 5.673597947631097e-09 8.246141443180955 0.10835782464838817 NPQMPQYSSPQPGSALS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 NPQMPQYSSPQPGSALSPR 19 0 O14497-2;O14497;H0Y488;A0A1B0GTU5;O14497-3;A0A087WUV6 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 NPQMPQYS(0.002)S(0.002)PQPGS(0.378)ALS(0.619)PR;NPQMPQYSSPQPGS(0.021)ALS(0.979)PR;NPQMPQY(0.003)S(0.026)S(0.026)PQPGS(0.003)ALS(0.943)PR;NPQMPQY(0.016)S(0.013)S(0.013)PQPGS(0.024)ALS(0.934)PR 145.19 5.9508e-11 54886000.0 115139.4 126526.6 157638.4 269874.0 212281.0 171621.0 157855.4 217475.0 166181.1 193819.4 True False 151751.33415170273 167423.84908748177 155548.0118168993 207658.71881173633 182809.4473867845 160889.51173964093 171904.22479357003 183869.23582834212 174965.09368056053 187033.8418000338 0.8113576275353784 0.8951527032550721 0.8316570430243452 1.1102735035179008 0.9774137430285702 0.8602160453489217 0.9191075964603265 0.9830800354564971 0.9354729176104049 1.0 17.512939808612707 NPQMPQYSSPQPGSALS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NPQMPQYSSPQPGSALSPR 19 0 O14497-2;O14497;H0Y488;A0A1B0GTU5;O14497-3;A0A087WUV6 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 NPQMPQY(0.176)S(0.052)S(0.052)PQPGS(0.015)ALS(0.706)PR;NPQMPQYS(0.001)S(0.001)PQPGS(0.047)ALS(0.952)PR;NPQMPQY(0.013)S(0.111)S(0.111)PQPGS(0.193)ALS(0.572)PR;NPQMPQYS(0.001)S(0.001)PQPGS(0.046)ALS(0.952)PR 128.72 4.8831e-06 48315800.0 106424.9 116298.9 116452.0 145703.4 158936.4 140135.2 152791.4 146168.3 145412.3 105645.9 True False 124440.5335824114 127844.28619934586 119228.65732666926 137540.11087479658 127793.95335449374 132786.26341807953 138317.8924780579 142331.53700311534 147538.67979445567 124798.66537751546 0.9971303235173172 1.0244042739769486 0.9553680479354731 1.1020960076675363 1.02400096161219 1.0640038738908115 1.108328298701327 1.1404892558150603 1.182213602590635 1.0 16.92924298024326 -6.6569247045571105 0.9342768725000627 1.1201723360066829 1.0036639816605846 0.3586042445797216 0.054671725882869296 0.5534250999688329 1.0517810365541838 0.030579366438242498 0.031424460686887035 2.2033084266985089e-07 6.6569247045571105 -0.1165083543460983 NPQMPQYSSPQPGSALS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 NPQMPQYSSPQPGSALSPR 19 0 O14497-2;O14497;H0Y488;A0A1B0GTU5;O14497-3;A0A087WUV6 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 NPQMPQYSSPQPGS(0.001)ALS(0.998)PR;NPQMPQY(0.035)S(0.013)S(0.013)PQPGS(0.167)ALS(0.771)PR 124.25 2.3493e-05 40405000.0 121228.0 110104.0 105904.0 110306.0 123134.0 108938.0 105551.0 104352.0 115975.0 97470.0 True False 119499.26648950775 109849.06095276981 97196.98192126189 118418.27121002915 115891.50021075828 104278.97568688125 111015.91431499048 109200.57487570534 102912.67422910857 114317.55962938869 1.0453273047195712 0.9609115284554227 0.8502366761184302 1.0358712309284308 1.0137681436384072 0.9121868593499373 0.9711186511932028 0.9552388559529057 0.9002350519268069 1.0 16.802687498675994 -8.00174150079581 23.22095296962019 0.9426573574819338 0.9666997636000311 0.014729617926376504 0.05904115758019938 120.29541896781099 1603943.8525400744 0.03343227364824607 0.015622428468291582 9.959980753570281e-09 8.00174150079581 0.02404240611809727 NPQNSSQS(ph)ADGLR ddPTM_PC-9_AZD4547_30min_R2 2 NPQNSSQSADGLR 13 0 P0DN76;Q01081 P0DN76 U2AF1 Splicing factor U2AF 35 kDa subunit 1 NPQNS(0.165)S(0.165)QS(0.67)ADGLR;NPQNS(0.279)S(0.279)QS(0.442)ADGLR 104.16 0.0013702 5911700.0 3002.5 2908.0 7167.0 8892.8 11890.7 2494.55 5944.3 6910.2 5234.5 7885.0 True False 3957.2325441203316 3847.954130960578 7071.960897165393 6842.702352390398 10239.881553422307 2338.5653941541077 6473.33118436504 5842.387370598952 5511.184983556453 7608.9485500072105 0.5200761337933586 0.5057143054222559 0.9294268256234551 0.8992967040608933 1.345768273516924 0.3073440934426993 0.8507523926362869 0.7678311046791629 0.7243030948804654 1.0 12.893481391939638 -5.252614159576531 23.52184891394252 0.8444700013988977 0.5128950939341115 0.23686553397639976 0.24385931272090128 426.730484492174 1137347.5810163529 0.06262021059158253 0.15982261361345057 5.589665771073819e-06 5.252614159576531 -0.33157490746478624 NPQNSSQS(ph)ADGLR ddPTM_PC-9_Lapatinib_30min_R1 2 NPQNSSQSADGLR 13 0 P0DN76;Q01081 P0DN76 U2AF1 Splicing factor U2AF 35 kDa subunit 1 NPQNS(0.072)S(0.224)QS(0.704)ADGLR;NPQNS(0.029)S(0.09)QS(0.88)ADGLR 107.13 0.0010421 4913000.0 5237.4 6068.799999999999 9991.9 5405.5 9299.7 6236.2 6458.1 6133.1 6046.0 6537.200000000001 True False 5162.713715578472 6054.748066465959 9170.404551849393 5803.038502219388 8752.709929913666 5969.492263292231 6792.468818274011 6418.066215982326 5365.035812797508 7667.1463097285405 0.6733553146139533 0.7897003424577052 1.1960648957765978 0.7568707140564332 1.1415863968589848 0.7785807159722226 0.8859187687152017 0.837086701715695 0.6997435024801893 1.0 12.904473995261661 NPQS(ph)PNLQNPTVTLQK ddPTM_PC-9_AZD4547_30min_R2 2 NPQSPNLQNPTVTLQK 16 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5;A0A087WZJ0 Q8NEV8-2 EXPH5 Exophilin-5 1 NPQS(0.999)PNLQNPT(0.001)VTLQK;NPQS(1)PNLQNPTVTLQK 208.37 2.9083e-63 4661500.0 39901.0 45910.0 51984.0 56450.0 48004.0 46087.0 49483.0 65961.0 55825.0 58441.0 True False 52588.68800764209 60749.50968101793 51294.65819425777 43436.32464380603 41339.473209355565 43205.17260442981 53886.891138727064 55768.24308298998 58775.795531003714 56394.99837805598 0.9325062420447738 1.0772144946927837 0.909560416163026 0.7702159037690063 0.7330343895433338 0.7661170998675213 0.9555260694837638 0.9888863318894983 1.0422164592857606 1.0 15.783279596514872 -7.49085633903368 5.98522478278466 1.005108791659728 0.8653990149706803 0.3289387841463085 0.09459219500809093 0.27052646593149987 30.034032922005924 0.0491488074413999 0.031503812282850555 3.229562257102478e-08 7.49085633903368 -0.13970977668904783 NPRQPTRTS(ph)S(ph)ES(ph)IY(ph)S(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 NPRQPTRTSSESIYSR 16 2 A0A3B3IS55 A0A3B3IS55 5 NPRQPTRT(0.026)S(0.985)S(0.995)ES(0.995)IY(0.999)S(0.999)R 53.358999999999995 0.016943 357560.0 0.0 0.0 1229.9 464.84 1003.5 0.0 0.0 791.12 0.0 579.33 True False 0.0 0.0 1213.5907223976158 357.67831970640896 864.1813466708669 0.0 0.0 668.870582129062 0.0 559.0478330343283 0.0 0.0 2.1708173266867763 0.6397991344766482 1.5458093129175978 0.0 0.0 1.1964460688428964 0.0 1.0 9.126827917439064 -6.781596684434643 24.996518609134366 0.4241117413739008 0.8822167358430727 0.08228321586882015 0.7199991032428457 672.2524759402907 833636.1892338116 0.2586090182771563 0.22834817496422757 1.6534966355303353e-07 6.781596684434643 0.4581049944691719 NPS(ph)PDHSYK ddPTM_PC-9_Lapatinib_30min_R1 2 NPSPDHSYK 9 0 Q15696 Q15696 ZRSR2 U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 1 NPS(1)PDHSYK;NPS(1)PDHSYK 60.301 0.040008999999999996 6353200.0 58378.0 83578.0 82050.0 67280.0 77719.0 75792.0 90040.0 78793.0 82627.0 63805.0 True False 57545.519014785954 83384.4802760171 75304.16572215938 72227.99563950073 73147.72122143295 72550.55283978129 94701.8306308965 82454.01042798859 73320.67715911672 74833.60923518175 0.7689796015843093 1.1142651160117412 1.0062880367763474 0.9651812384527347 0.9774715127203004 0.9694915637674854 1.265498638897321 1.1018312663345955 0.9797827194020498 1.0 16.191398737722096 NPS(ph)PGTSAK ddPTM_PC-9_Lapatinib_30min_R1 1 NPSPGTSAK 9 0 Q9P212;Q9P212-2 Q9P212 PLCE1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 1 NPS(0.438)PGT(0.438)S(0.124)AK 68.132 0.043881 3201500.0 30670.0 32443.0 26739.0 33025.0 35111.0 30363.0 27017.0 30676.0 29909.0 19737.0 True False 30232.640175810822 32367.880226791985 24540.62263552487 35453.768668170436 33045.84001088194 29064.44526960999 28415.808064803736 32101.318948243792 26540.333464267376 23148.514152100604 1.3060294054798922 1.3982703172270248 1.06013813561757 1.5315785901080479 1.4275577168257776 1.2555641834563513 1.2275434992541476 1.3867550520658696 1.1465242775359292 1.0 14.498631972853898 -8.495808034656934 3.699030773865693 1.000852956820257 1.3220951287833382 0.42840698367307417 0.1215953197024287 0.1866203936394147 6.208383518207132 0.11655668491814822 0.03068858529919157 3.192948879437259e-09 8.495808034656934 0.32124217196308114 NPS(ph)SSVPPPSAGSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NPSSSVPPPSAGSVK 15 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 NPS(0.951)S(0.046)S(0.003)VPPPSAGSVK;NPS(0.939)S(0.055)S(0.006)VPPPSAGSVK 115.2 0.00016378 9030700.0 31259.0 23986.0 18362.699999999997 28421.0 37752.0 41206.0 51397.0 65575.0 51003.0 39751.0 True False 36550.53130660767 26367.17156204842 18800.536408927557 26828.66351212521 30354.766604999568 39045.08482098276 46528.30407794387 63853.72573245564 51748.82238680379 46957.54163125712 0.7783740382668999 0.5615109021060253 0.4003730978202029 0.571338757952925 0.6464300632125517 0.8314976351954622 0.99085902842436 1.3598183276688327 1.1020343184311288 1.0 15.519069260543581 -7.097804545266314 1.6392151162809023 1.1702233623576828 0.5690247340638414 0.7964746002279457 0.1251115927699408 0.15770415169758353 0.8426190624341408 0.06456420327747882 0.04490197445098056 7.98353906527034e-08 7.097804545266314 -0.6011986282938414 NPSDSAVHS(ph)PFTK ddPTM_PC-9_AZD4547_30min_R2 1 NPSDSAVHSPFTK 13 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 NPSDSAVHS(0.998)PFT(0.002)K 77.506 0.0090917 32514000.0 51556.0 42184.0 98015.0 96896.0 86762.0 105220.0 72927.0 112150.0 90909.0 90469.0 True False 67949.73556858217 55819.1530469192 96715.25705813679 74558.12422827678 74716.59392113371 98640.57676650923 79417.36172168126 94819.79445061958 95714.26414559821 87301.7078466205 0.7783322599823864 0.6393821429586156 1.1078277784445507 0.8540282437460125 0.8558434395396084 1.1298814101072328 0.9096885236335678 1.0861161458285276 1.0963618754601874 1.0 16.41372225651699 -4.068732252219001 0.4091734610025159 1.0522829627324894 0.19671209871644632 0.426393778583009 0.11859272220020643 9.127711643753385 0.7685220494552397 0.08883956884356829 4.28751362213019 8.536262226765639e-05 4.068732252219001 -0.8555708640160431 NPSDSAVHS(ph)PFTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NPSDSAVHSPFTK 13 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 NPSDS(0.001)AVHS(0.993)PFT(0.006)K;NPSDSAVHS(0.996)PFT(0.004)K;NPSDSAVHS(0.5)PFT(0.5)K 99.055 0.009036399999999998 44126000.0 138829.0 193530.0 245481.0 223888.0 292609.0 170008.0 256136.0 180000.0 193393.0 144520.0 True False 162330.00770226298 212742.37940478718 251334.19803187737 211344.2812146897 235274.3669612817 161092.4811980206 231872.94381594757 175275.19072576464 196221.00676138964 170720.3319803091 0.9508533975964043 1.2461455348465753 1.4721983908798062 1.2379561283835026 1.3781273983723172 0.9436045451024605 1.358203449620118 1.0266802359895886 1.1493710472869851 1.0 17.3812753611586 -6.747311994446166 24.999884965313022 1.1136538028728944 1.2673412277446532 0.19144694790742722 0.16315514677286677 431.119760981837 762910.2577736566 0.053653486699864035 0.05340568060390562 1.7893199559075327e-07 6.747311994446166 0.1536874248717588 NPSDSAVHS(ph)PFTK ddPTM_PC-9_Lapatinib_30min_R1 1 NPSDSAVHSPFTK 13 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 NPS(0.002)DS(0.001)AVHS(0.996)PFT(0.001)K 78.488 0.014941 12261000.0 13327.0 9872.8 18069.0 18691.0 16818.0 16179.0 16459.0 20873.0 17115.0 13172.0 True False 13136.954536127518 9849.940138183027 16583.436568357036 20065.59849134819 15828.798305460188 15487.061885091074 17311.166485494494 21842.835780632813 15187.328471060098 15448.762649413251 0.850356422339524 0.6375876412702302 1.073447559826863 1.2988482603239613 1.024599747220621 1.0024791134763973 1.1205535924362187 1.4138890134002033 0.9830773386654962 1.0 13.915203671333341 -5.349094921540034 5.591118800261116 1.1320665987287055 0.7461071006515219 0.5237967070579761 0.14121876546752418 0.15200705041867615 7.477535620907455 0.03700559273916459 0.07925565755935081 4.476154604454641e-06 5.349094921540034 -0.38595949807718366 NPSDSAVHS(ph)PFTKR ddPTM_PC-9_AZD4547_30min_R2 1 NPSDSAVHSPFTKR 14 1 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 NPSDSAVHS(0.997)PFT(0.003)KR 69.069 0.011207 21136000.0 28334.0 21433.0 53346.0 81991.0 63334.0 45554.0 35584.0 54807.0 33062.0 55508.0 True False 37343.62261618834 28360.79810484115 52638.59718434281 63089.24169832243 54541.16732441722 42705.50117868806 38750.90706465783 46337.83748956858 34809.58982258924 53564.68181532026 0.6971687565500955 0.5294682455619396 0.9827109095099194 1.1778141783020544 1.0182300253824652 0.7972697630488617 0.7234413750139093 0.8650819144101645 0.6498608531383677 1.0 15.708994444329505 -5.261685173552393 24.999905752010967 0.9008951564985145 0.6133184901581736 0.36913350397931566 0.15085020333753787 24.307510245369464 2472664.7081290204 0.043237862781501935 0.10010385762664156 5.474126465620164e-06 5.261685173552393 -0.28757666634034085 NPSINQILLS(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NPSINQILLSPEK 13 0 Q14997-3;Q14997-2;Q14997 Q14997-3 PSME4 Proteasome activator complex subunit 4 1 NPSINQILLS(1)PEK 80.102 0.013132 2109900.0 11448.0 12786.0 5267.9 7488.7 6908.0 8033.3 10880.0 6962.8 7233.6 9744.7 True False 13385.920291693421 14055.30958026979 5393.506714622004 7069.132417692977 5554.426989492927 7612.019606183584 9849.367635621333 6780.0338776964145 7339.377715373287 11511.33697099724 1.162846707156535 1.2209971453083233 0.46853868740103083 0.6141017707590025 0.48251797367128424 0.6612628598539017 0.8556232573537521 0.5889875254958375 0.6375782182265027 1.0 13.49076778290766 -5.251619457984774 24.983201389293598 0.647440152183142 1.1919220125907926 0.6557770525778831 0.15275829880478675 375.509530784723 955342.014412635 0.037928601948646806 0.09773288199982055 5.6024829305425575e-06 5.251619457984774 0.5444818604076506 NPT(ph)RWSTTAGFLK ddPTM_PC-9_AZD4547_30min_R2 1 NPTRWSTTAGFLK 13 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 NPT(0.99)RWS(0.002)T(0.003)T(0.005)AGFLK 60.301 0.041783 6932200.0 17776.0 16688.0 24255.0 39916.0 30042.0 26081.0 24416.0 26598.0 24472.0 31707.0 True False 23428.39823623081 22082.0696483735 23933.362852064525 30713.98289605244 25871.186862666847 24450.150947037862 26588.9766999406 22487.89026123568 25765.53995942182 30596.94758085968 0.765710310622186 0.7217082550478737 0.782214068537881 1.003825065061914 0.8455479682833102 0.799104253207695 0.8690074926485046 0.7349716896368863 0.8420951106750201 1.0 14.90110011319904 -12.303653790620027 1.612364173536166 4.283776248498887 0.8190859626524303 0.33497085722165854 0.07682166415769802 2551347.5987991616 69791.8388310139 30693039.983175904 0.02201379042679866 4.96988351039351e-13 12.303653790620027 -3.4646902858464568 NPVSLPSLPNPTKPNNVPS(ph)VPSPSIQR ddPTM_PC-9_AZD4547_30min_R2 1 NPVSLPSLPNPTKPNNVPSVPSPSIQR 27 1 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 NPVSLPS(0.004)LPNPT(0.131)KPNNVPS(0.473)VPS(0.367)PS(0.025)IQR 70.533 9.212100000000001e-05 8902100.0 17035.0 12249.0 12772.0 29104.0 18170.0 18846.0 14209.0 17824.0 13340.0 17314.0 True False 22451.77564998828 16208.24970774969 12602.634934923448 22394.522452317615 15647.409137030047 17667.55664076821 15473.573473519651 15069.710354773477 14045.125165850231 16707.842129971443 1.343786676659642 0.9700983275796247 0.7542945903418701 1.3403599506213368 0.9365308227901475 1.0574409611565085 0.9261263874263156 0.90195431807083 0.8406307084177744 1.0 14.028237796406549 -7.243558910181625 1.8253342767674088 0.9005560364383857 1.061608130806513 0.1546244169557185 0.17018114155929454 0.740656516249082 4.819887946257658 0.08913889193408864 0.05639293926622847 5.70743651995217e-08 7.243558910181625 0.1610520943681274 NPVSLPSLPNPTKPNNVPS(ph)VPSPSIQR ddPTM_PC-9_Lapatinib_30min_R1 1 NPVSLPSLPNPTKPNNVPSVPSPSIQR 27 1 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 NPVSLPSLPNPT(0.002)KPNNVPS(0.47)VPS(0.456)PS(0.07)IQR 84.125 4.6887e-07 6396400.0 16857.0 15024.0 17605.0 12161.0 14504.0 16611.0 13210.0 14101.0 15701.0 12647.0 True False 16616.61608880481 14989.212851071805 16157.584857265243 13055.360507906755 13650.903235961145 15900.58625213225 13893.949162973588 14756.183938231374 13932.588041140207 14833.017098931776 1.120245192058835 1.0105302752028296 1.0892986065814525 0.8801554276403388 0.9203052315596829 1.071972488542291 0.9366906995593084 0.994820125926644 0.9392956232851363 1.0 13.856524457514103 -5.736852803556186 24.999993668717174 0.9647294472704149 1.0670752976587454 0.4515123193324688 0.055432963891884714 226.81074065139254 230622.63858430032 0.014992198935943923 0.025952159061742003 1.8329355582365652e-06 5.736852803556186 0.10234585038833055 NPVSLPSLPNPTKPNNVPSVPS(ph)PSIQR ddPTM_PC-9_AZD4547_30min_R2 1 NPVSLPSLPNPTKPNNVPSVPSPSIQR 27 1 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 NPVSLPS(0.001)LPNPT(0.005)KPNNVPS(0.182)VPS(0.59)PS(0.221)IQR 52.059 0.005762399999999999 8816200.0 18853.0 16136.0 19403.0 34424.0 29019.0 27225.0 19122.0 25337.0 23209.0 27418.0 True False 24847.861833239185 21351.646443321846 19145.70354230501 26488.078645498288 24990.212754401473 25522.616446190947 20823.82095577752 21421.748836338396 24435.780357887405 26458.104165389694 0.9391399201513125 0.8069983514258102 0.7236234093956678 1.0011329035489929 0.944520159047964 0.9646426775950759 0.7870488688685987 0.8096479136385198 0.9235650523234493 1.0 14.691422069692894 -12.683368296599491 0.9745661902673893 2.6950165911910138 0.8746417177784163 0.15146754310953914 0.08649164048611907 51080.792652129574 1088.08467351132 189374.8555801656 0.028276136880560424 2.0731546655947342e-13 12.683368296599491 -1.8203748734125975 NPVSLPSLPNPTKPNNVPSVPS(ph)PSIQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NPVSLPSLPNPTKPNNVPSVPSPSIQR 27 1 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 NPVSLPSLPNPTKPNNVPS(0.061)VPS(0.67)PS(0.268)IQR;NPVSLPSLPNPT(0.001)KPNNVPS(0.04)VPS(0.752)PS(0.207)IQR 75.766 2.3831999999999998e-05 14823600.0 36374.0 28774.8 35857.0 41950.0 46498.0 53080.0 46859.0 47874.0 44499.0 38706.0 True False 42531.39978075266 31631.37197797179 36711.96686842976 39599.677503734994 37387.050688685864 50296.39135800043 42420.17629021873 46617.35822669589 45149.71369116287 45723.091403472594 0.9301951918658429 0.6918030038443429 0.8029196132972222 0.8660761179574893 0.8176842278395546 1.1000216698860503 0.9277626465781137 1.0195583193474835 0.9874597780965839 1.0 15.480635329070433 -6.740993863409057 24.841723003321658 1.0032329952573578 0.8159350952151112 0.6466380519258046 0.0683668961880152 136.76507387850705 166171.97634192894 0.021864713701749697 0.021839168053128875 1.8155413162321363e-07 6.740993863409057 -0.18729790004224656 NPWGEVEWTGR ddPTM_PC-9_AZD4547_30min_R2 1 NPWGEVEWTGR 11 0 P17655;P17655-2 P17655 CAPN2 Calpain-2 catalytic subunit 0 97.45200000000001 0.02481 2723500.0 2206.0 4027.8 4612.8 5713.2 3711.7 4348.6 4814.1 5035.9 4110.2 4170.7 False True 2907.4621123495253 5329.707582078067 4551.631258050022 4396.110008060099 3196.3945236056356 4076.6813545603654 5242.545573852555 4257.717368469688 4327.456780860391 4024.6850624622803 0.72240736038381 1.3242545688326186 1.1309285540134557 1.092286710595582 0.7941974276243366 1.0129193443191489 1.302597716961534 1.0579007555599493 1.075228673473615 1.0 11.97466017929294 NPWGEVEWTGR ddPTM_PC-9_Lapatinib_30min_R1 2 NPWGEVEWTGR 11 0 P17655;P17655-2 P17655 CAPN2 Calpain-2 catalytic subunit 0 ; 124.39 0.0023689 7125800.0 10086.9 11917.5 18097.9 12534.5 14749.1 14209.5 10825.5 11738.9 12313.9 8993.599999999999 False True 9943.058956289082 11889.905760959016 16609.960521914254 13456.32894386624 13881.586935846275 13601.792808962333 11385.991420421695 12284.332148961363 10926.978910884429 10548.131776781276 0.9426369680151238 1.1272048939634292 1.5746826901116628 1.275707322265971 1.3160232759323935 1.2894978084083881 1.079432041746457 1.1645979031094245 1.0359160410696686 1.0 13.36469987942555 -7.26508724475204 23.945644060175535 1.0837029695511897 1.2668580511539562 0.2509710264181466 0.15434974067666077 284.1583820933348 1865279.028295363 0.06657537635688017 0.04689853295878336 5.4314120972798174e-08 7.26508724475204 0.1831550816027665 NPYYGGESASITPLEDLYK ddPTM_PC-9_Lapatinib_30min_R1 1 NPYYGGESASITPLEDLYK 19 0 P50395;P50395-2;Q5SX87;V9GYJ7;V9GYF8;Q5SX90 P50395 GDI2 Rab GDP dissociation inhibitor beta 0 113.11 0.00043833 2605200.0 8762.9 10457.0 10188.0 9570.6 9714.9 6769.9 11008.0 9660.4 7828.7 8159.7 False True 8637.939439080954 10432.787458976167 9350.381966817282 10274.453850585676 9143.488682228279 6480.367158407696 11577.940377442334 10109.257451024057 6946.949366134274 9570.093272883187 0.9025972049359763 1.0901448043915538 0.9770418845667412 1.0736001789761331 0.9554231522629262 0.677147753279457 1.2098043401779972 1.0563384454850184 0.7259019497561661 1.0 13.224317270362967 -6.499440320992203 23.879525414346464 0.9392384402357057 1.0141476616128573 0.05447439929678666 0.1509784029429147 1555.865071314027 1585146.560688964 0.04762651265341881 0.05362075945836328 3.1663555414314034e-07 6.499440320992203 0.07490922137715161 NQAAIQGRPPYAAS(ph)AEEVAK ddPTM_PC-9_AZD4547_30min_R2 1 NQAAIQGRPPYAASAEEVAK 20 1 Q9NZB2-4;Q9NZB2;Q9NZB2-6;A0A0C4DG79;A0A494C0Y9 Q9NZB2-4 FAM120A Constitutive coactivator of PPAR-gamma-like protein 1 1 NQAAIQGRPPY(0.133)AAS(0.867)AEEVAK 57.482 0.0089251 10253000.0 8922.7 11221.0 12255.0 21328.0 11846.0 12840.0 13515.0 12457.0 12463.0 13250.0 True False 11759.932996310576 14847.968811385375 12092.490692725254 16411.15911431522 10201.387376844132 12037.112770214575 14717.808817975803 10532.056883382698 13121.768736281225 12786.121532986115 0.919742000415987 1.1612566620049738 0.9457512711363327 1.2835134619968298 0.797848460186008 0.9414201749264451 1.1510768750325302 0.8237100559549433 1.026250900433661 1.0 13.642291091487051 -6.277403325425228 24.99375320306364 0.9568563441155451 1.0741284657359789 0.16325909527284432 0.133939399612832 1538.8967437999456 2409349.6427594 0.039812358918822524 0.045271996429930475 5.27954717179623e-07 6.277403325425228 0.11727212162043377 NQAAIQGRPPYAAS(ph)AEEVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NQAAIQGRPPYAASAEEVAK 20 1 Q9NZB2-4;Q9NZB2;Q9NZB2-6;A0A0C4DG79;A0A494C0Y9 Q9NZB2-4 FAM120A Constitutive coactivator of PPAR-gamma-like protein 1 1 NQAAIQGRPPY(0.049)AAS(0.951)AEEVAK;NQAAIQGRPPY(0.005)AAS(0.995)AEEVAK 67.827 0.002531 16270900.0 43939.0 39044.0 36689.0 46240.0 57569.0 56601.0 59212.0 45472.0 43700.0 44311.0 True False 51377.00486519194 42920.030287193345 37563.80490380734 43649.32271210269 46288.767712524335 53632.74391963413 53603.01070224357 44278.40818156652 44339.02982772236 52344.23353431699 0.9815217722408538 0.8199571832311745 0.7176302405723531 0.83388980533044 0.8843145574416964 1.0246160904137107 1.0240480580750375 0.8459080435772834 0.8470661777606048 1.0 15.675742991974497 -6.513670062862856 5.4138185548138615 0.9448440010468039 0.8311371580805098 0.2745796785206325 0.08411259923378005 0.2478381030397567 23.8349780981072 0.029440441426977115 0.03138338388135249 3.064290516668714e-07 6.513670062862856 -0.11370684296629407 NQAAIQGRPPYAAS(ph)AEEVAK ddPTM_PC-9_Lapatinib_30min_R1 1 NQAAIQGRPPYAASAEEVAK 20 1 Q9NZB2-4;Q9NZB2;Q9NZB2-6;A0A0C4DG79;A0A494C0Y9 Q9NZB2-4 FAM120A Constitutive coactivator of PPAR-gamma-like protein 1 1 NQAAIQGRPPY(0.007)AAS(0.993)AEEVAK 67.217 0.0026603 13622000.0 22502.0 23236.0 23175.0 15716.0 25411.0 24713.0 29537.0 24021.0 21863.0 19255.0 True False 22181.117353638587 23182.198469615592 21269.640958087024 16871.80706703911 23916.37493994819 23656.082598816727 31066.281334349034 25137.103352971833 19400.558712403566 22583.20109432525 0.9821954496615761 1.0265240243306721 0.9418346349239081 0.7470954625329307 1.0590338738983263 1.047507946283181 1.375636748952983 1.113088585093826 0.8590703608125145 1.0 14.462962377422341 -6.501047411924993 23.45749947484802 1.0989544001773093 0.9292147653693278 0.21670118384256298 0.1386862310932836 528.283866494212 567634.9061155613 0.045441427994641445 0.05099760595270072 3.154660210346148e-07 6.501047411924993 -0.1697396348079815 NQEASLGMKT(ph)PEAPAHSEKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NQEASLGMKTPEAPAHSEKPR 21 2 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;Q9NUQ6-2 B8ZZZ7 SPATS2L SPATS2-like protein 1 NQEAS(0.02)LGMKT(0.98)PEAPAHSEKPR 47.485 0.017078 8953200.0 45849.0 37107.0 26043.0 43515.0 39773.0 32101.0 46519.0 34610.0 27483.0 30565.0 True False 53610.330140972386 40790.737728380365 26663.963888627488 41076.995627533455 31979.766162869462 30417.56704941919 42112.38355160554 33701.52417232619 27884.886882272163 36106.192547593106 1.4847959964293198 1.1297435384418437 0.7384872789752225 1.137671760138877 0.8857141644252734 0.8424473726861259 1.1663479469926223 0.9334001121248878 0.7723020599725632 1.0 15.139958673491005 -4.8639410364473425 3.3407156106046907 0.9417554246948755 1.5119595456682773 0.6122175079523706 0.13359003535114866 0.1768234691837798 3.294226876773375 0.03305567501576894 0.23035523009079648 1.367914532826415e-05 4.8639410364473425 0.5702041209734018 NQEIQQGEDAFPPS(ph)SPLFAEPYK ddPTM_PC-9_AZD4547_30min_R2 1 NQEIQQGEDAFPPSSPLFAEPYK 23 0 Q9UHB7;Q9UHB7-2;Q9UHB7-3;C9JCE0 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 NQEIQQGEDAFPPS(0.494)S(0.494)PLFAEPY(0.012)K 82.26700000000001 0.00095602 0.0 6944.6 9643.9 9961.6 12907.0 11606.0 9681.1 8258.2 10966.0 8424.5 10801.0 True False 9152.838343346562 12761.102078256778 9829.502675206186 9931.490561162165 9994.707234142581 9075.739286582886 8993.16380174678 9271.456673611194 8869.801871042373 10422.86027756854 0.8781503444927452 1.2243378245912462 0.9430715190877745 0.9528565380979086 0.9589217324204754 0.8707532332669903 0.8628306973567833 0.8895309374495475 0.8509949893630863 1.0 13.347463620890105 -5.909562582166671 1.3613409470553077 0.8916617487480353 1.0470501831287458 0.23329666720356523 0.09180468017943262 0.5228500877168161 1.9656497100456356 0.030674693672879835 0.06188897070939572 1.2315085116321088e-06 5.909562582166671 0.15538843438071048 NQGETPTTEVPAPFFLPASLSANNTPT(ph)RR ddPTM_PC-9_AZD4547_30min_R2 1 NQGETPTTEVPAPFFLPASLSANNTPTRR 29 1 Q9UJX2-3;Q9UJX2 Q9UJX2-3 CDC23 Cell division cycle protein 23 homolog 1 NQGETPTTEVPAPFFLPAS(0.013)LS(0.013)ANNT(0.144)PT(0.83)RR 81.904 1.1366e-06 3933200.0 6173.5 3691.8 7706.7 10128.0 7910.8 6424.8 6647.5 6621.8 5521.0 8290.0 True False 8136.544583222939 4885.102152916186 7604.5041225316745 7793.146076040166 6812.521970347677 6023.056240348485 7239.114622086135 5598.552963826245 5812.828788655106 7999.769623279614 1.0170973623471986 0.610655354211747 0.9505903895535063 0.9741713128040379 0.851589769600739 0.7529037114795377 0.9049153866906434 0.6998392738128679 0.7266245232537156 1.0 12.965742738644877 -6.534160002045602 23.394624407893094 0.8034497910719721 0.8777843737090463 0.05434779082759611 0.1317105155228694 312.8577095057901 648782.2766452065 0.042676198137406016 0.042723690769091494 2.923075264948343e-07 6.534160002045602 0.07433458263707415 NQGETPTTEVPAPFFLPASLSANNTPT(ph)RR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NQGETPTTEVPAPFFLPASLSANNTPTRR 29 1 Q9UJX2-3;Q9UJX2 Q9UJX2-3 CDC23 Cell division cycle protein 23 homolog 1 NQGETPTTEVPAPFFLPAS(0.161)LS(0.136)ANNT(0.136)PT(0.567)RR 60.574 0.013431 0.0 1323.9 3671.0 3651.6 3691.5 5060.9 4655.2 3754.4 5648.0 3786.6 3161.0 True False 1548.0101217830993 4035.432619206194 3738.6679927701184 3484.677223004478 4069.252974974632 4411.073116988762 3398.7560524978608 5499.745984550664 3841.9718614566045 3734.0642775377664 0.41456440134015415 1.0807078612656205 1.00123289662153 0.9332129722475657 1.0897651118255223 1.1813061557412219 0.9102028781194396 1.4728578770414695 1.0288981591902302 1.0 11.866531046743296 -4.761395065383941 9.471017744149766 1.0840784526445104 0.41087572020229 0.6315393356391299 0.15185705128277746 0.049661050287949364 74.92927187558286 0.03748970156853524 0.21348972374079278 1.7322275225328918e-05 4.761395065383941 -0.6732027324422204 NQGETPTTEVPAPFFLPASLSANNTPT(ph)RR ddPTM_PC-9_Lapatinib_30min_R1 1 NQGETPTTEVPAPFFLPASLSANNTPTRR 29 1 Q9UJX2-3;Q9UJX2 Q9UJX2-3 CDC23 Cell division cycle protein 23 homolog 1 NQGETPT(0.001)T(0.001)EVPAPFFLPAS(0.133)LS(0.133)ANNT(0.323)PT(0.408)RR 44.843999999999994 0.024131 2647500.0 6302.7 4367.8 4049.3 3119.5 5027.0 5568.9 3548.6 3650.9 6412.8 3413.5 True False 6212.822342226374 4357.686627456832 3716.382184750022 3348.918436346941 4731.321743462261 5330.73112873995 3732.3291445668474 3820.53414226572 5690.522934222272 4003.518926797153 1.551840382379978 1.0884641004914684 0.9282789098047695 0.836493719045835 1.1817907770570617 1.3315114093901828 0.9322621455801984 0.9542940128728647 1.4213803002486953 1.0 11.967052911278222 -4.762896607772815 6.088610501335546 1.0672450003663123 1.568513711843691 0.39265905617939145 0.17788898742705395 0.13725457392265142 20.364628906850022 0.045292290786083995 0.2872699090339284 1.7262488100950288e-05 4.762896607772815 0.5012687114773786 NQGGGLSS(ph)SGAGEGQGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NQGGGLSSSGAGEGQGPK 18 0 P07814 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 NQGGGLS(0.094)S(0.812)S(0.094)GAGEGQGPK 230.27 1.0941999999999998e-96 0.0 7809.4 11025.0 7121.1 8580.2 9079.2 6855.3 6204.1 8935.4 6946.7 7010.3 True False 9131.377177319233 12119.489138313344 7290.894030922136 8099.47921138372 7300.195935582538 6495.795999934067 5616.402734205725 8700.855217838882 7048.28234563476 8281.211896495737 1.1026619402388738 1.4634922146409277 0.8804138961843662 0.9780548200694009 0.8815371502173102 0.7844016167105707 0.678210243187033 1.0506741436625622 0.851117255992121 1.0 13.015626196000877 -5.278284763896093 24.75747751072878 0.8816465938850458 1.2830770597341352 0.596385859039881 0.129903101107366 397.23659624775456 583814.1463101797 0.033411734575392905 0.06985231418132432 5.26884273751539e-06 5.278284763896093 0.40143046584908937 NQGGGLSS(ph)SGAGEGQGPK ddPTM_PC-9_Lapatinib_30min_R1 1 NQGGGLSSSGAGEGQGPK 18 0 P07814 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 NQGGGLS(0.029)S(0.96)S(0.01)GAGEGQGPK 275.31 1.584699999999999e-196 0.0 11581.0 10536.0 11643.0 12569.0 12868.0 10407.0 12122.0 9698.6 11686.0 13119.0 True False 11415.8528163047 10511.60453932991 10685.757483279709 13493.366188954864 12111.129539461394 9961.916869901894 12749.617846598467 10149.232362480014 10369.799620964548 15386.601670031307 0.7419346429523493 0.6831660924714458 0.694484572515613 0.876955579816957 0.7871217959096456 0.6474410063727623 0.8286181783357056 0.6596149416311863 0.6739499626588727 1.0 13.909387008540357 -10.738880899025888 4.363902194236802 1.0001008161963392 0.7340371319095454 0.5480772722506024 0.07283673263908239 107102492.62305057 19.81930671934962 108498.05703437702 0.0180221338157329 1.8243959563014035e-11 10.738880899025888 -0.2660636842867937 NQGGYGGS(ph)SSSSSYGSGR ddPTM_PC-9_Lapatinib_30min_R1 1 NQGGYGGSSSSSSYGSGR 18 0 F8W6I7;P09651-2;P09651;P09651-3;A0A2R8Y4L2;H0YH80 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 NQGGYGGS(0.199)S(0.199)S(0.199)S(0.199)S(0.199)S(0.004)YGSGR 243.61 2.5706999999999995e-53 64788000.0 45136.0 44468.0 48039.0 39950.0 42343.0 36602.0 39886.0 42215.0 41204.0 33315.0 True False 44492.35236307133 44365.0370781058 44089.41885590259 42888.05626929326 39852.46798954101 35036.617783429356 41951.10191630312 44176.46301343431 36563.17162264449 39073.45336055286 1.138684926374826 1.1354265687428367 1.128372720196103 1.0976264594158314 1.0199371839954798 0.896685979100098 1.0736471519217041 1.1306004259667835 0.9357548022504031 1.0 15.253901147893492 -6.138845977356262 3.1110962031402787 1.013343385459989 1.1324328956692562 0.4689946180952208 0.06108407683038068 0.26269540972455435 4.8301503322176185 0.019934112406568817 0.026878708421889653 7.263635167587725e-07 6.138845977356262 0.11908951020926728 NQGGYGGSS(ph)SSSSYGSGR ddPTM_PC-9_AZD4547_30min_R2 2 NQGGYGGSSSSSSYGSGR 18 0 F8W6I7;P09651-2;P09651;P09651-3;A0A2R8Y4L2;H0YH80 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 NQGGYGGS(0.028)S(0.902)S(0.035)S(0.035)S(0.001)SYGSGR;NQGGYGGS(0.147)S(0.393)S(0.034)S(0.393)S(0.034)SYGSGR 278.07 9.277699999999998e-92 132134000.0 57697.0 56991.0 65649.0 99146.0 84545.0 73092.0 65985.0 71854.0 62135.0 64821.0 True False 76043.44582784691 75412.22623025256 64778.4513657054 76289.42149043034 72807.38610292808 68521.54568539886 71857.53717011712 60750.61534065832 65419.32924888342 62551.636519976826 1.2156907486115294 1.2055995722217197 1.0355996256791364 1.2196231103572508 1.163956535008895 1.0954396958665573 1.1487714977236179 0.971207449084992 1.0458452070712931 1.0 15.93276000923822 -7.751809328118327 24.79045796977258 1.0063947492525849 1.1528562150321018 0.599721087216713 0.05586493295876994 120.73979810373878 310820.3380526242 0.02683036750468333 0.01523200882524083 1.770886274448889e-08 7.751809328118327 0.1464614657795169 NQGGYGGSSS(ph)SSSYGSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NQGGYGGSSSSSSYGSGR 18 0 F8W6I7;P09651-2;P09651;P09651-3;A0A2R8Y4L2;H0YH80 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 NQGGYGGS(0.104)S(0.104)S(0.583)S(0.104)S(0.104)S(0.001)YGSGR;NQGGY(0.001)GGS(0.044)S(0.044)S(0.39)S(0.39)S(0.13)S(0.001)YGSGR;NQGGYGGS(0.042)S(0.042)S(0.392)S(0.392)S(0.104)S(0.028)YGSGR 216.34 1.6268000000000003e-27 150768100.0 23517.699999999997 27345.7 21140.399999999998 28357.4 36255.4 26012.9 26105.1 29918.9 25002.300000000003 20164.800000000003 True False 27498.782114252135 30060.400374564662 21644.46731141346 26768.626813931252 29151.414631566582 24648.73773090673 23632.235943442847 29133.5605766949 25367.91133779549 23820.518615531044 1.154415760550354 1.2619540682445596 0.9086480299090217 1.1237633926441062 1.2237942885323991 1.034769147084635 0.9920957777986649 1.2230447643444564 1.0649604967565878 1.0 14.53991720315911 -14.52274382099353 0.015061651549670863 2.305014750727524e-06 1.9478270262352813 0.10327767873383265 0.10542535584353267 15943.988749656932 18.14834365663252 1471.3725910442204 932.5007309994787 3.000932168747565e-15 14.52274382099353 1.9478247212205306 NQGGYGGSSSS(ph)SSYGSGR ddPTM_PC-9_AZD4547_30min_R2 1 NQGGYGGSSSSSSYGSGR 18 0 F8W6I7;P09651-2;P09651;P09651-3;A0A2R8Y4L2;H0YH80 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 NQGGYGGS(0.135)S(0.135)S(0.272)S(0.308)S(0.149)SYGSGR 200.99 4.521100000000001e-15 19694000.0 7509.1 8604.0 9457.8 13797.0 11697.0 10789.0 7859.8 11098.0 10094.0 12369.0 True False 9896.837601017141 11385.074739609641 9332.383392383263 10616.31481152509 10073.073454916917 10114.362124442756 8559.306973549847 9383.059106669436 10627.548232690573 11935.965074830596 0.8291610723532219 0.9538461840523798 0.7818708695841015 0.8894391651590656 0.8439261837451282 0.8473853652413026 0.7171022133433418 0.7861165015014596 0.890380305745106 1.0 13.543027598870987 -6.692334767035876 3.0506020469168726 0.8260788759220007 0.863972397402304 0.0 0.08062274474969718 0.9698566824700865 18.27269988819267 0.02819135245703811 0.02728468896460647 2.0307910136580514e-07 6.692334767035876 0.03789352148030334 NQGGYGGSSSS(ph)SSYGSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NQGGYGGSSSSSSYGSGR 18 0 F8W6I7;P09651-2;P09651;P09651-3;A0A2R8Y4L2;H0YH80 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 NQGGYGGS(0.041)S(0.041)S(0.137)S(0.34)S(0.34)S(0.101)YGSGR 188.16 1.5691e-42 0.0 2018.9 3331.6 2843.8 4194.1 3695.5 2935.0 2276.1 3704.5 2283.5 2436.0 True False 2360.6598949073946 3662.3392302226516 2911.606977171557 3959.11817445566 2971.3933033687194 2781.0834332277905 2060.4913304630254 3607.260800242199 2316.8918675424266 2877.6275166346104 0.8203493611529645 1.2726939845591143 1.011808151103825 1.3758271880461634 1.032584407186851 0.9664501111249699 0.7160382358564507 1.2535537623927422 0.8051395999479581 1.0 11.49066414474513 -6.517230035911019 20.261606940292893 0.9551201019310654 1.1334342200652132 0.15190512152702695 0.19021623914207025 38.209416255604694 137062.2751657833 0.058763373306968125 0.06092900195252427 3.039274764526231e-07 6.517230035911019 0.17831411813414777 NQGGYGGSSSS(ph)SSYGSGR ddPTM_PC-9_Lapatinib_30min_R1 2 NQGGYGGSSSSSSYGSGR 18 0 F8W6I7;P09651-2;P09651;P09651-3;A0A2R8Y4L2;H0YH80 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 NQGGYGGS(0.21)S(0.21)S(0.065)S(0.367)S(0.112)S(0.035)YGS(0.001)GR;NQGGYGGSSS(0.003)S(0.889)S(0.086)S(0.022)YGSGR 274.16 1.7709999999999998e-91 59408000.0 64274.8 56035.0 62626.9 51764.4 66457.7 57013.0 50963.9 52386.7 57967.2 49668.7 True False 63358.22956544523 55905.25440028016 57477.95802882499 55571.32665697627 62548.788746865306 54574.686893794285 53602.56137372212 54820.77732905082 51438.32351432281 58253.86861561732 1.0876226947863077 0.9596831202604882 0.9866805311779017 0.9539508358433403 1.073727637894534 0.9368422765859591 0.9201545347556844 0.9410667245257233 0.8830027041419988 1.0 15.830066241286126 -6.956721399325754 24.22918096794901 0.9307668008479987 1.0047940783907 0.3713367651061903 0.04884045780637338 109.27853109935585 61178.171564187425 0.016547952806106433 0.014593909317104341 1.1047871155055668e-07 6.956721399325754 0.07402727754270122 NQGGYGGSSSSSS(ph)YGSGR ddPTM_PC-9_AZD4547_30min_R2 1 NQGGYGGSSSSSSYGSGR 18 0 F8W6I7;P09651-2;P09651;P09651-3;A0A2R8Y4L2;H0YH80 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 NQGGYGGSSSS(0.008)S(0.237)S(0.755)YGSGR 134.08 4.8331e-05 16716000.0 30579.0 27692.0 29242.0 51784.0 41065.0 37164.0 30716.0 38084.0 30447.0 42011.0 True False 40302.48591728747 36642.89745342517 28854.231973616625 39845.99885482462 35363.83358349692 34840.1292050042 33449.664495223435 32198.99288325814 32056.36626121756 40540.20767715318 0.9941361484440624 0.9038655584903583 0.7117435658791088 0.9828760417840733 0.872315057315963 0.8593969099136779 0.8250984987941814 0.7942483457331717 0.790730193503257 1.0 15.307065858932248 -6.874533713059028 2.9171998006039805 0.8361488785745179 0.888921759595112 0.03208847455198771 0.09085360898388542 0.8300602890501985 14.22257736951077 0.03462744168737637 0.03017885452266471 1.3349539568194114e-07 6.874533713059028 0.052772881020594076 NQGGYGGSSSSSSYGS(ph)GR ddPTM_PC-9_AZD4547_30min_R2 4 NQGGYGGSSSSSSYGSGR 18 0 F8W6I7;P09651-2;P09651;P09651-3;A0A2R8Y4L2;H0YH80 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 NQGGYGGSSSSSSY(0.007)GS(0.992)GR;NQGGYGGS(0.001)S(0.001)S(0.008)S(0.001)S(0.02)S(0.129)YGS(0.84)GR;NQGGYGGSSSSSSYGS(1)GR;NQGGYGGSSSSSSYGS(1)GR 220.89 4.8759e-28 22020700.0 25144.5 25726.8 32022.800000000003 57864.0 47237.0 40009.0 37278.4 43426.3 41170.7 42519.1 True False 33139.92796190961 34042.48498500573 31598.15674867419 44524.34878988825 40678.95791997186 37507.230905258155 40596.105382170135 36715.763172099396 43346.899150350124 41030.519250806814 0.8076897043231535 0.8296869161444094 0.7701134990645494 1.0851519698721028 0.9914317113881506 0.9141300570920906 0.9894124208864811 0.8948403247755006 1.0564550471658425 1.0 15.324409791538216 -5.747552032976132 24.999998640400438 0.9826699681702309 0.8052156788255831 0.7061289592467055 0.05533380177749178 133.36924365897266 240089.2729081934 0.014963326997812307 0.02574875308388502 1.7883312556690087e-06 5.747552032976132 -0.1774542893446478 NQGGYGGSSSSSSYGS(ph)GR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NQGGYGGSSSSSSYGSGR 18 0 F8W6I7;P09651-2;P09651;P09651-3;A0A2R8Y4L2;H0YH80 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 NQGGYGGSSSSSSYGS(1)GR;NQGGYGGSSSSSSYGS(1)GR;NQGGYGGSSSSSSYGS(1)GR 258.68 1.7154999999999998e-67 11429800.0 39905.0 43703.4 36788.6 51059.7 59007.0 54489.6 55251.8 55916.0 48965.5 41281.8 True False 46660.12834032375 48041.98472629149 37665.77974554245 48198.990546780864 47445.00193529375 51632.06945254141 50017.9495156087 54448.26424789925 49681.52780387506 48765.863553450996 0.956819482734696 0.9851560338644249 0.7723800421222515 0.9883756184067407 0.9729142165869885 1.0587748414615654 1.0256754596539714 1.1165241478441148 1.0187767463488149 1.0 15.5735839839919 -6.419876364905207 1.8885580660847703 1.050172715121502 0.9148590579316587 0.4401744273011774 0.06336213303347156 0.3078055614325705 2.180332270406172 0.023026471666271017 0.0269203900617685 3.802976441692247e-07 6.419876364905207 -0.13531365718984323 NQGGYGGSSSSSSYGS(ph)GR ddPTM_PC-9_Lapatinib_30min_R1 3 NQGGYGGSSSSSSYGSGR 18 0 F8W6I7;P09651-2;P09651;P09651-3;A0A2R8Y4L2;H0YH80 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 NQGGYGGSSSSSSYGS(1)GR;NQGGYGGSSSSSSYGS(1)GR;NQGGYGGSSSSSSYGS(1)GR 246.9 2.0968999999999997e-96 10497000.0 21486.300000000003 20161.2 25023.699999999997 20067.7 21028.1 19023.0 19674.6 21082.6 23711.9 19440.300000000003 True False 21179.90142189517 20114.51798010044 22966.347980275383 21543.545601884754 19791.268500835253 18209.430634778888 20693.254519442853 22062.174561815238 21041.216124623414 22800.52995242852 0.9289214534085541 0.8821951955532513 1.0072725514798486 0.9448703888389278 0.8680179163435302 0.7986406751409466 0.9075777871223902 0.967616744340864 0.9228389063115738 1.0 14.476779736871709 -8.559495273680023 1.1943598770562138 0.996434865511506 0.9076440347124228 0.19642993464720848 0.053729671301588906 0.9765478315146728 3.0365727851024134 0.05634021771261572 0.01759056915253843 2.7574314606311235e-09 8.559495273680023 -0.08879083079908312 NQGGYGGSSSSSSYGSGR ddPTM_PC-9_AZD4547_30min_R2 1 NQGGYGGSSSSSSYGSGR 18 0 F8W6I7;P09651-2;P09651;P09651-3;A0A2R8Y4L2;H0YH80 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 0 249.36 1.6486999999999998e-131 0.0 1038.5 1116.2 2086.4 2339.2 3169.9 499.68 600.26 1188.8 872.96 1011.5 False True 1368.7213978581055 1476.989821519325 2058.7329727704578 1799.9335802797348 2729.8141014568823 468.43493060909805 653.6819771422977 1005.0982759063459 919.1028834168384 976.087692876639 1.4022524900650384 1.5131732858617155 2.1091680468822864 1.8440285574907007 2.7966893972526345 0.47991070272443265 0.6696959524362244 1.0297212875865789 0.9416191702080987 1.0 9.930866956820049 -6.780378463093453 24.99999991742993 0.816391020796362 1.9145727383657716 0.6757259451276941 0.38395479755563805 154.05759173903266 203358.0060811534 0.14095673932416916 0.12451141815935893 1.6581413012257083e-07 6.780378463093453 1.0981817175694095 NQGGYGGSSSSSSYGSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NQGGYGGSSSSSSYGSGR 18 0 F8W6I7;P09651-2;P09651;P09651-3;A0A2R8Y4L2;H0YH80 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 0 ;;; 217.79 3.1430999999999993e-81 7710700.0 6352.300000000001 7177.15 6296.09 10279.78 11106.5 7219.900000000001 9934.7 9395.029999999999 8453.23 5819.42 False True 7427.618926356061 7889.650019868087 6446.212663654288 9703.837254096425 8930.26105367736 6841.27573409245 8993.613295000665 9148.42041735712 8576.842496810012 6874.434779496627 1.0804697643665682 1.1476798126588377 0.937708025520944 1.41158328871468 1.299053862626255 0.9951764695618212 1.3082694917441944 1.3307887427549356 1.2476433004195353 1.0 12.747025383737387 -5.75182264565776 24.999998829675246 1.237951428042686 1.0645253074872827 0.2474108765314157 0.13651046252178392 288.1093619836689 748971.5973739946 0.037028904640628024 0.06309216448144343 1.7708319714651277e-06 5.75182264565776 -0.1734261205554033 NQGGYGGSSSSSSYGSGR ddPTM_PC-9_Lapatinib_30min_R1 3 NQGGYGGSSSSSSYGSGR 18 0 F8W6I7;P09651-2;P09651;P09651-3;A0A2R8Y4L2;H0YH80 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 0 ;; 290.39 1.6504999999999993e-131 23682700.0 30596.56 23123.63 33889.7 28174.0 27648.29 24500.27 28955.7 27208.75 21105.4 24704.6 False True 30160.247443678098 23070.088655446598 31103.419684025095 30246.009945708844 26022.071940829563 23452.450565018862 30454.884464671795 28472.967855425326 18728.287602285225 28974.75719318969 1.0409145879147195 0.79621335570222 1.073466102809508 1.043874491994637 0.8980945644281659 0.8094097358141519 1.0510833364922898 0.9826818449445952 0.646365644323231 1.0 14.822508951129812 -6.299374948216171 22.440607323476733 0.9003039438870296 0.98093465728507 0.10699479852621141 0.1274575198828504 452.97783813615433 267954.69328521413 0.03969297787970388 0.04500984631300303 5.019090791232839e-07 6.299374948216171 0.0806307133980404 NQGIEEALK ddPTM_PC-9_Lapatinib_30min_R1 1 NQGIEEALK 9 0 P18206;P18206-2;P18206-3 P18206 VCL Vinculin 0 98.03299999999999 0.021159 4461200.0 19575.0 22007.0 21268.0 13350.0 16862.0 17346.0 16788.0 15200.0 16644.0 17996.0 False True 19295.856910384657 21956.044143606057 19519.427136854152 14331.803534294482 15870.210311967518 16604.152015500946 17657.200495685134 15906.247490328122 14769.377450909975 21106.584621837286 0.9142102929538294 1.0402461855856064 0.9248027327291489 0.6790204948396301 0.7519080228426861 0.7866811382795663 0.8365730795410948 0.7536154131669037 0.6997521254873841 1.0 14.365405526317039 -5.5949293735025325 6.36909296986237 0.7777038806069673 0.9786465410392722 0.4502899511425582 0.08836360216707674 0.15565579848329408 10.661243629331235 0.02277031444315192 0.03991476883767243 2.5413859610771365e-06 5.5949293735025325 0.2009426604323049 NQGIEGS(ph)PGGR ddPTM_PC-9_AZD4547_30min_R2 1 NQGIEGSPGGR 11 0 Q6ZUT6;Q6ZUT6-4;H0YM82;Q6ZUT6-3 Q6ZUT6 C15orf52 Uncharacterized protein C15orf52 1 NQGIEGS(1)PGGR 92.295 0.0077247 36642000.0 150190.0 144770.0 155730.0 263070.0 180040.0 173570.0 132870.0 175920.0 167580.0 174790.0 True False 197947.2958539325 191564.07136835041 153664.9184478256 202423.27589098396 155044.5537166148 162716.64046153752 144695.1725967032 148735.60623943826 176437.9366786496 168670.65530193507 1.173572815612708 1.1357285060962985 0.9110352845475823 1.2001096191191574 0.9192147468631793 0.9647003515238656 0.8578562307574268 0.8818108044531436 1.0460499863643171 1.0 17.36384947513494 -6.28437323961306 24.628863989807563 0.9356631711580979 1.0934358958696082 0.43295554326094654 0.08902362029082082 636.8735877938824 683941.8646898541 0.02746673171348827 0.031166286283380328 5.195492956486344e-07 6.28437323961306 0.15777272471151027 NQGIEGS(ph)PGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NQGIEGSPGGR 11 0 Q6ZUT6;Q6ZUT6-4;H0YM82;Q6ZUT6-3 Q6ZUT6 C15orf52 Uncharacterized protein C15orf52 1 NQGIEGS(1)PGGR;NQGIEGS(1)PGGR 81.23899999999999 0.042903 0.0 62807.0 62566.0 64280.0 77188.0 91467.0 82467.0 69909.0 70899.0 56760.0 68345.0 True False 73438.98460520529 68777.13899571093 65812.67898325743 72863.40660687233 73544.69795135333 78142.28534514362 63286.71342267021 69037.97637369984 57590.0076206298 80735.40748127754 0.9096254901820582 0.8518832212701755 0.8151650067353574 0.9024963009416814 0.9109348704087271 0.9678812281125199 0.7838780455445938 0.8551139893572679 0.7133178541767423 1.0 16.300913903048247 -10.551987322268964 4.597506641734652 1.000004262293768 0.8593600200700855 0.27781618366665817 0.0691933141372064 99649453.10932657 11364.12661815683 5100.647720440559 0.017055783948912953 2.8055155341159747e-11 10.551987322268964 -0.14064424222368244 NQGIEGS(ph)PGGR ddPTM_PC-9_Lapatinib_30min_R1 3 NQGIEGSPGGR 11 0 Q6ZUT6;Q6ZUT6-4;H0YM82;Q6ZUT6-3 Q6ZUT6 C15orf52 Uncharacterized protein C15orf52 1 NQGIEGS(1)PGGR;NQGIEGS(1)PGGR;NQGIEGS(1)PGGR 96.23 0.0058909 62975000.0 260684.0 245142.0 234956.0 266713.0 237344.0 250042.0 215093.0 172166.0 216329.0 198605.0 True False 256966.59835640911 244574.38876047978 215638.8246363876 286327.96374848596 223383.8925562577 239348.28653637093 226229.46308186822 180165.4608828834 191963.7499746398 232933.6096254716 1.1031752728581314 1.0499746651147728 0.9257522990482486 1.2292256330413882 0.9590024080914357 1.0275386489790517 0.971218637987095 0.7734627097075735 0.8241135758952679 1.0 17.82955929321129 -7.541572947756127 3.9003275115139973 0.8494537999224788 1.0457629020738906 0.4253718473388547 0.0943323368710755 0.19279079297172422 6.570049786026803 0.044921612775294106 0.025873264666929 2.8736048782165823e-08 7.541572947756127 0.19630910215141173 NQHSLYTAT(ph)TPPSSSPSR ddPTM_PC-9_AZD4547_30min_R2 1 NQHSLYTATTPPSSSPSR 18 0 F6SS63;Q8N5C8-2;Q8N5C8 F6SS63 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 1 NQHSLYTAT(0.5)T(0.5)PPSSSPSR 100.95 0.001166 3759900.0 6881.1 7597.6 12071.0 18180.0 18786.0 21758.0 9162.6 20032.0 21259.0 16487.0 True False 9069.146664228614 10053.375620834282 11910.930652948718 13988.881878200056 16177.888169964039 20397.46882043058 9978.053649691828 16936.514689565884 22382.707338891334 15909.79514825224 0.5700354140150509 0.6318984956848227 0.7486539293535269 0.8792622248022341 1.0168508154387677 1.2820698588737849 0.6271641813557832 1.0645338001995854 1.4068507564253692 1.0 13.95762763944825 -5.7533520720216265 1.2905349781977444 1.0628939547435456 0.5772743925011725 0.4985817203664784 0.19092214743596866 0.43419504041793977 1.4308791146397255 0.06802566567993587 0.1735109372195265 1.7646067167421163e-06 5.7533520720216265 -0.4856195622423731 NQHSLYTATT(ph)PPSSSPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NQHSLYTATTPPSSSPSR 18 0 F6SS63;Q8N5C8-2;Q8N5C8 F6SS63 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 1 NQHSLYTAT(0.236)T(0.723)PPS(0.004)S(0.017)S(0.017)PS(0.004)R 96.633 0.013586 0.0 13718.0 12700.0 15262.0 20858.0 26156.0 21335.0 20739.0 15002.0 18214.0 13665.0 True False 16040.186457149748 13960.772068623994 15625.903961457321 19689.393882548375 21030.919562417046 20216.155041879036 18774.451782642525 14608.213395932904 18480.34529249738 16142.356327919517 0.9936706966012726 0.8648534194774095 0.968006382961021 1.2197348071479484 1.302840746120959 1.2523670417876698 1.1630552195264445 0.9049616486700155 1.1448356681690963 1.0 13.978563566249367 -5.6557798411131275 5.7271745393706714 1.1489378943978388 0.9271430766901843 0.390365540735498 0.11403218600755925 0.2169966117487523 10.17819999559116 0.03409195552277197 0.05967351102666768 2.2091243307084157e-06 5.6557798411131275 -0.22179481770765452 NQIPRT(ph)PENLITEIR ddPTM_PC-9_AZD4547_30min_R2 2 NQIPRTPENLITEIR 15 1 Q5VY60;Q7Z4H7-3;Q7Z4H7;Q5SYF9 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 NQIPRT(1)PENLITEIR;NQIPRT(1)PENLITEIR 84.40299999999999 0.0044091 7219300.0 16853.4 7974.5 16858.6 36402.0 23278.2 18318.6 17667.3 28147.0 20243.6 23036.2 True False 22212.430627502934 10552.101175153079 16635.043948786442 28010.081305293632 20046.423740980346 17173.13504614117 19239.65547390484 23797.5279037146 21313.63536787151 22229.70964967356 0.9992227058993152 0.4746846153839906 0.7483248414371766 1.2600291117929627 0.9017852260285696 0.7725307850070527 0.8654928821433064 1.070528058114518 0.9587905421960604 1.0 14.440201484472531 -5.551129821964866 24.999555943346454 0.9656216405090408 0.7055911607776533 0.2809551480590494 0.17024450142415173 237.21985625730784 209916.24537290653 0.04595870874545873 0.07960450642595167 2.8110604054096966e-06 5.551129821964866 -0.2600304797313875 NQIPRT(ph)PENLITEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NQIPRTPENLITEIR 15 1 Q5VY60;Q7Z4H7-3;Q7Z4H7;Q5SYF9 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 NQIPRT(1)PENLITEIR 79.676 0.007660800000000001 2721200.0 5518.5 4745.3 4984.1 8905.9 9092.8 9695.3 9980.5 11557.0 9668.7 6478.2 True False 6452.673054656726 5216.382023404835 5102.939846304509 8406.931296317367 7311.131113210955 9186.861400399794 9035.07478743738 11253.64099565368 9810.086446116695 7652.646378597017 0.8431949858160981 0.6816442006250353 0.6668202859309496 1.0985652387950318 0.9553729195770478 1.2004816302623993 1.180647104341153 1.4705554704746262 1.2819207841033429 1.0 12.901743020318476 -6.276352687495306 1.000814956086842 1.271766086027864 0.7177679028951904 0.660434047716583 0.14368606369414927 0.3039095730277945 0.6432272524269569 0.06578075882820675 0.10076549272805412 5.292334825407679e-07 6.276352687495306 -0.5539981831326735 NQIPRT(ph)PENLITEIR ddPTM_PC-9_Lapatinib_30min_R1 3 NQIPRTPENLITEIR 15 1 Q5VY60;Q7Z4H7-3;Q7Z4H7;Q5SYF9 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 NQIPRT(1)PENLITEIR;NQIPRT(1)PENLITEIR;NQIPRT(1)PENLITEIR 77.77600000000001 0.0090647 9876300.0 47914.0 31280.5 38384.0 30591.5 39234.8 40750.2 33671.4 32556.1 41960.0 34238.1 True False 47230.73757364854 31208.071924118205 35228.215686524796 32841.30096025241 36927.08620258469 39007.40893935586 35414.74033657446 34068.77525788628 37234.02294161154 40156.10996559943 1.1761781112291438 0.7771687036133044 0.8772815822225754 0.8178406969297224 0.9195882328796052 0.9713941159333503 0.8819265702507846 0.8484082568523695 0.9272318203508467 1.0 15.2933318977136 NQKDPGVLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NQKDPGVLDR 10 1 P31949 P31949 S100A11 Protein S100-A11;Protein S100-A11, N-terminally processed 0 80.24 0.023237999999999998 9777600.0 85646.0 36161.0 49801.0 105630.0 109270.0 120270.0 100850.0 128750.0 123060.0 94057.0 False True 100144.17621439326 39750.82510027653 50988.44471134426 99711.89355708032 87859.32790125818 113962.82947676552 91296.7579092288 125370.44892190097 124859.51969335256 111108.78954519771 0.9013164181188008 0.35776490107568293 0.45890559081829235 0.8974257929118985 0.7907504731254233 1.0256868960885117 0.8216879896085124 1.12835761630633 1.1237591571687604 1.0 16.76161342376227 -6.264520048253518 1.1655282194926964 1.0287160685477041 0.560829604665758 0.531058871601081 0.1691638578157509 0.3653788342898221 1.024467912945908 0.07124323456731241 0.10472992768723458 5.438510254495367e-07 6.264520048253518 -0.4678864638819461 NQKDPGVLDR ddPTM_PC-9_Lapatinib_30min_R1 1 NQKDPGVLDR 10 1 P31949 P31949 S100A11 Protein S100-A11;Protein S100-A11, N-terminally processed 0 79.48899999999999 0.024571 7258600.0 141280.0 66694.0 84954.0 74630.0 63972.0 67288.0 41510.0 44431.0 75735.0 47312.0 False True 139265.32129242082 66539.57414066701 77969.41005192329 80118.53915838189 60209.29273379109 64410.24909598916 43659.18469001013 46495.426463340016 67204.92677509421 55489.81616072274 2.5097455880741726 1.1991312774931413 1.4051120628349143 1.4438422164947098 1.085051220198652 1.1607580192630114 0.7867963477037673 0.8379091819059007 1.2111218134231945 1.0 15.759935402858318 -2.0612820984223834 0.879939730033266 1.0534188336581576 199.99999983136104 0.7942244473832384 0.20949399034858965 126.46281746027691 0.8969423193322242 0.07454608290588118 49687.00897460617 0.008683961744313401 2.0612820984223834 198.94658099770288 up NQKNSLS(ph)DPNIDR ddPTM_PC-9_AZD4547_30min_R2 1 NQKNSLSDPNIDR 13 1 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 NQKNS(0.403)LS(0.597)DPNIDR 188.12 0.00014625 13521000.0 21128.0 17486.0 26774.0 37316.0 23354.0 26348.0 20046.0 23163.0 19861.0 22309.0 True False 27846.264510299552 23138.007542632964 26418.959266179172 28713.372726452893 20111.700219383598 24700.455394829696 21830.055165752332 19583.69058278826 20910.81191296488 21527.968700331112 1.2934924282880094 1.07478823779027 1.227192385585958 1.3337706462761285 0.9342126282018549 1.1473658169360768 1.0140322791075302 0.9096859464723697 0.9713323260565341 1.0 14.393924578097222 -6.686382722476291 1.0689793731726158 0.9655792417939993 1.2156776274260206 0.5209763567513259 0.09979664992047436 0.4186459550678786 1.0240817082995117 0.052715867544669434 0.05146809496671339 2.0588147808679685e-07 6.686382722476291 0.25009838563202125 NQKNSLS(ph)DPNIDR ddPTM_PC-9_Lapatinib_30min_R1 1 NQKNSLSDPNIDR 13 1 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 NQKNS(0.077)LS(0.923)DPNIDR 178.68 0.00058328 8094100.0 9187.0 7424.6 9183.5 5954.1 11663.0 21965.0 25033.0 21419.0 28384.0 23096.0 True False 9055.99169531054 7407.408794866066 8428.468079335147 6391.984376295339 10977.005270340236 21025.608152915836 26329.086252590303 22414.204933903824 25187.09502322931 27088.11282651446 0.3343160800203966 0.2734560669584751 0.31115006546654556 0.23597008832740532 0.4052332970053083 0.7761931695860146 0.971979348329456 0.8274553889174697 0.9298209581649265 1.0 14.725372266973975 -6.779369288349367 2.6032519896546242 0.9170908325496094 0.289432800472586 0.9726338632701566 0.05019304327064089 0.039404156562161695 0.5472763568774723 0.01815592221785379 0.01664240953488243 1.661998822091423e-07 6.779369288349367 -0.6276580320770234 down NQKPSQVNGAPGS(ph)PTEPAGQK ddPTM_PC-9_AZD4547_30min_R2 5 NQKPSQVNGAPGSPTEPAGQK 21 1 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 NQKPSQVNGAPGS(0.795)PT(0.205)EPAGQK;NQKPSQVNGAPGS(0.919)PT(0.081)EPAGQK;NQKPSQVNGAPGS(0.994)PT(0.006)EPAGQK;NQKPSQVNGAPGS(0.949)PT(0.051)EPAGQK;NQKPSQVNGAPGS(0.968)PT(0.032)EPAGQK 156.31 6.2087e-06 457119000.0 314538.0 263541.0 301220.0 369237.0 316700.0 311242.0 329368.0 308699.0 274782.0 322090.0 True False 414554.54120317084 348725.4744248566 297225.6259863484 284115.114304783 272731.6716399243 291779.98853793857 358681.1139296383 260996.6627473194 289306.4155414291 310813.7271365658 1.3337716613173372 1.1219757815639626 0.956282171719375 0.9141009212245896 0.8774762754287588 0.938761589541172 1.1540066689912973 0.839720514122088 0.9308032119646801 1.0 18.245690696440214 -4.900550517044905 2.0180173545531432 0.9472303914069498 1.3934833973301137 0.6930470611244761 0.07991956095669986 0.31901050220162375 1.7563063896365607 0.02235690461755592 0.2438998085415052 1.2573305934250072e-05 4.900550517044905 0.44625300592316397 NQKPSQVNGAPGS(ph)PTEPAGQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 NQKPSQVNGAPGSPTEPAGQK 21 1 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 NQKPSQVNGAPGS(0.919)PT(0.081)EPAGQK;NQKPSQVNGAPGS(0.99)PT(0.01)EPAGQK;NQKPSQVNGAPGS(0.947)PT(0.053)EPAGQK;NQKPSQVNGAPGS(0.989)PT(0.011)EPAGQK;NQKPSQVNGAPGS(0.5)PT(0.5)EPAGQK;NQKPSQVNGAPGS(0.732)PT(0.268)EPAGQK 123.85 8.870499999999999e-07 536271000.0 253811.0 244360.0 200760.6 287458.0 293717.0 262849.0 301108.0 260698.0 242498.0 211833.0 True False 296776.18930424575 268618.44588102034 205547.49409281518 271352.6602114101 236165.26231512614 249064.7357207811 272584.87040686223 253854.95373236394 246044.07448885604 250236.64603089436 1.1859821253662646 1.0734576655405481 0.8214124403962726 1.0843841799969967 0.9437676937452599 0.9953167918100669 1.0893083596285444 1.0144595436314425 0.9832455733061548 1.0 17.932933555609743 -4.9925972916423405 8.227512737108741 0.993945984895819 1.1594966782460416 0.415507309681585 0.07130506985048651 0.12293833466829861 68.43667317771418 0.017465003774109474 0.061863370991177814 1.017191467097248e-05 4.9925972916423405 0.16555069335022266 NQKPSQVNGAPGS(ph)PTEPAGQK ddPTM_PC-9_Lapatinib_30min_R1 6 NQKPSQVNGAPGSPTEPAGQK 21 1 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 NQKPSQVNGAPGS(0.987)PT(0.013)EPAGQK;NQKPSQVNGAPGS(0.999)PT(0.001)EPAGQK;NQKPSQVNGAPGS(0.92)PT(0.08)EPAGQK;NQKPSQVNGAPGS(0.961)PT(0.039)EPAGQK;NQKPSQVNGAPGS(0.984)PT(0.016)EPAGQK;NQKPSQVNGAPGS(0.973)PT(0.027)EPAGQK 135.8 9.5059e-07 1046356000.0 465609.0 430443.0 397004.0 410461.0 409861.0 421076.0 370958.0 358172.0 427564.0 299287.0 True False 458969.33027776657 429446.33567983826 364363.86359975697 440647.67119775666 385753.78179772984 403067.5610560983 390164.39012856566 374813.9786911721 379407.2398714774 351018.3591751403 1.307536538420101 1.2234298419290555 1.0380193915098268 1.2553408096181542 1.0989561420781937 1.148280568581281 1.1115213205526195 1.0677902420031513 1.080875771748943 1.0 18.421186963651138 -1.5228787452803376 0.16575362666836643 1.0000359157665122 2.0378858495099603 0.5768186794545992 0.06141886151045413 47.6838752714129 0.5068013956848719 0.16916196445693774 12.18769467196664 0.029999999999999995 1.5228787452803376 1.0378499337434481 NQKPSQVNGAPGSPT(ph)EPAGQK ddPTM_PC-9_AZD4547_30min_R2 1 NQKPSQVNGAPGSPTEPAGQK 21 1 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 NQKPSQVNGAPGS(0.198)PT(0.802)EPAGQK 92.147 0.00029444 387300000.0 13546.0 13458.0 13735.0 19030.0 15770.0 18364.0 15732.0 14394.0 15403.0 15388.0 True False 17853.346225696587 17808.035314466106 13552.864925710419 14642.927510569141 13580.60771001452 17215.696176964208 17132.11752307772 12169.738041214625 16217.171134152273 14849.270803742675 1.202304575198181 1.1992531855488615 0.9126956538697171 0.9861041463987897 0.9145639465738348 1.1593630693720725 1.15373460081014 0.8195512225521076 1.0921190237883485 1.0 13.85810446655838 -5.24226331638422 23.768254956840895 1.0052754324563067 1.2007789985980424 0.3692206925718292 0.10247830779329217 471.88093255627456 584879.6983016689 0.026539700163840354 0.06992423400452617 5.724488452130707e-06 5.24226331638422 0.1955035661417357 NQKPSQVNGAPGSPT(ph)EPAGQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NQKPSQVNGAPGSPTEPAGQK 21 1 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 NQKPSQVNGAPGS(0.378)PT(0.622)EPAGQK 125.19 4.7417e-06 239190000.0 20074.0 19374.0 12426.0 23600.0 24513.0 16776.0 21237.0 16372.0 19855.0 17514.0 True False 23472.13172042748 21297.32268169457 12722.282965867425 22277.76851223233 19709.853618042856 15896.237027539835 19225.277617434767 15942.252347567899 20145.34181303038 20689.14955925229 1.1345140917080674 1.0293957526238822 0.6149253708777003 1.076785125866597 0.9526662060997336 0.7683368995914556 0.9292444603571018 0.7705610277459879 0.9737153165883168 1.0 14.336586723062222 -5.011360893192749 24.42867425435297 0.8800205991463529 1.1082346836589976 0.2861480257027528 0.12845666283206347 436.07817968953515 937693.7548136472 0.030864632048053772 0.09454529820062323 9.741797702660515e-06 5.011360893192749 0.2282140845126447 NQLTSNPENTVFDAK ddPTM_PC-9_Lapatinib_30min_R1 2 NQLTSNPENTVFDAK 15 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 ; 239.38 1.4210999999999999e-31 13744500.0 51383.0 53952.0 49707.0 45355.0 45901.0 41091.0 50705.0 42124.0 40782.0 45358.0 False True 50650.26899751181 53827.07745880102 45620.2823345688 48690.55799984471 43201.19342483815 39333.63371779946 53330.25679852958 44081.23482122246 36188.70170650149 53198.06986426405 0.9521072686799915 1.0118238800043289 0.8575552167770348 0.9152692592810162 0.8120819709261421 0.7393808425410926 1.002484806960155 0.8286247026197872 0.6802634343471049 1.0 15.69908628227273 -5.441766150623142 1.722005317455752 0.8431740631064092 0.9863032309799623 0.19426363232408683 0.09859534174154737 0.6334772801448664 3.50227795197005 0.029117257088154623 0.09557698738489498 3.6160451910612497e-06 5.441766150623142 0.14312916787355312 NQLVT(ph)PEPTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NQLVTPEPTSR 11 0 Q14676;Q14676-3;Q14676-2 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 NQLVT(0.59)PEPT(0.396)S(0.014)R 103.11 0.0074362 13895000.0 52012.0 51112.0 36675.0 50378.0 46435.0 33420.0 42180.0 37089.0 33793.0 34944.0 True False 60816.60431617384 56186.06157255982 37549.47109071204 47555.48398767968 37336.39508643661 31667.396367452384 38184.40504324519 36115.45304904384 34287.15869492498 41279.0705834482 1.4733036247322795 1.361127098512943 0.9096491408352679 1.15204832171653 0.9044872997069732 0.7671538123280848 0.9250306390996147 0.8749095495266593 0.8306184759080601 1.0 15.33312286775865 -4.804569825036663 0.8133100870323647 0.8776915914898039 1.868644674449 0.7903488336063421 0.10187895948331312 1.0319658321247918 0.5353495368800578 0.03804569444811866 0.92292244647815 1.5683037285334785e-05 4.804569825036663 0.990953082959196 NQLVTPEPT(ph)SR ddPTM_PC-9_AZD4547_30min_R2 2 NQLVTPEPTSR 11 0 Q14676;Q14676-3;Q14676-2 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 NQLVT(0.491)PEPT(0.502)S(0.007)R;NQLVT(0.188)PEPT(0.406)S(0.406)R 135.91 0.00018644 33270000.0 78966.0 88254.0 80498.0 118266.0 105407.0 93189.0 77016.0 105253.0 72610.0 87271.0 True False 104075.54540516435 116780.37959896654 79430.54392354113 91001.60089148555 90773.05750726082 87361.8770984054 83870.27480023862 88988.56732332663 76448.01636374703 84215.66885322497 1.2358216329855682 1.3866823263316579 0.9431801113160595 1.080578022245331 1.0778642352822059 1.037358941489425 0.995898696077706 1.0566747083422219 0.9077647592751917 1.0 16.36180106027316 -5.261332018315922 24.99999999999349 1.0195118909062917 1.3112519934704632 0.7830952842329769 0.06282150884727918 3.803082427497769 885283.9431479867 0.015656226176445884 0.03638532195058608 5.478579671306423e-06 5.261332018315922 0.2917401025641715 NQLVTPEPT(ph)SR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NQLVTPEPTSR 11 0 Q14676;Q14676-3;Q14676-2 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 NQLVT(0.083)PEPT(0.614)S(0.303)R 79.23 0.042814 10986000.0 26178.0 24396.0 26969.0 17696.0 20193.0 20559.0 24470.0 21768.0 20377.0 14624.0 True False 30609.418360932068 26817.87365245281 27612.043240502073 16704.550491206082 16236.326606663393 19480.849847948943 22152.024452541722 21196.613065102483 20674.97507550342 17275.215436479702 1.7718689803598522 1.552390113516158 1.5983617305399453 0.9669662617307475 0.9398624674964974 1.1276762318582523 1.2823009087205806 1.2269955846884577 1.1967998402986348 1.0 14.076416081896868 -5.74402876472799 18.557015223604477 1.116610778689446 1.6320350833651058 0.8103621336065086 0.11851287766976021 5.657752882150035 6028.697707666267 0.03578105618179075 0.06147676424916867 1.8028983251185474e-06 5.74402876472799 0.5154243046756599 NQLVTPEPT(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 2 NQLVTPEPTSR 11 0 Q14676;Q14676-3;Q14676-2 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 NQLVT(0.046)PEPT(0.932)S(0.022)R;NQLVT(0.072)PEPT(0.894)S(0.034)R 116.19 0.003143 27265000.0 104599.0 84158.0 103027.0 79710.0 82253.0 78895.0 72707.0 76106.0 83890.0 61573.0 True False 103107.39907889249 83963.13732165225 94556.51775572069 85572.13930476522 77415.04025561987 75520.84476322771 76471.4127019167 79642.16259861265 74441.42479913705 72215.81100913478 1.4277676541754845 1.162669727700372 1.3093603247599057 1.1849501945486836 1.071995719134518 1.0457660685092198 1.0589289469067047 1.1028355354001147 1.0308189267544299 1.0 16.140027116484802 -1.5228787452803376 0.2861982069196579 1.0094873442600458 3.9939080981266355 0.7890563497245089 0.059353546466312725 24.289537191271346 0.34389557439450974 0.06500046393675274 36.51993463710216 0.029999999999999995 1.5228787452803376 2.9844207538665897 NQNYLVPS(ph)PVLR ddPTM_PC-9_AZD4547_30min_R2 2 NQNYLVPSPVLR 12 0 J3KR59;J3KR68;Q9UID6;C9J3R1;C9IZP0 J3KR59 ZNF639 Zinc finger protein 639 1 NQNYLVPS(1)PVLR;NQNYLVPS(1)PVLR 96.866 0.0041499 20243400.0 88976.0 102184.0 113070.0 128783.0 117026.0 115062.0 104689.0 116794.0 110038.0 104366.0 True False 117268.51718423018 135212.97968296957 111570.6179213745 99094.06902751591 100778.95991579958 107867.15495065638 114006.11819053415 98746.1709591235 115854.38403297079 100712.17810653818 1.1643926225106354 1.3425683191950708 1.1078165522678871 0.9839333324981756 1.0006630956704239 1.0710438099804507 1.1319993305073097 0.9804789531477023 1.150351290291969 1.0 16.619878618870175 -5.451510486392761 5.634628395202616 1.047199065282518 1.2508357543388653 0.5876035563321138 0.06875343173464338 0.13914677042106605 8.059348479043136 0.01742009726242172 0.03657433779416323 3.5358148348541035e-06 5.451510486392761 0.20363668905634724 NQNYLVPS(ph)PVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NQNYLVPSPVLR 12 0 J3KR59;J3KR68;Q9UID6;C9J3R1;C9IZP0 J3KR59 ZNF639 Zinc finger protein 639 1 NQNYLVPS(1)PVLR;NQNYLVPS(1)PVLR 107.11 0.0015914000000000002 11800900.0 66785.0 74434.0 63575.0 81592.0 91632.0 76783.0 94469.0 77866.0 73024.0 62447.0 True False 78090.38143612363 81823.31560283121 65090.86910953011 77020.66476483304 73677.36738581592 72756.36431125372 85520.21242366836 75822.10000584676 74091.83785216478 73768.14676981994 1.058592154684195 1.1091957597653355 0.8823709413852338 1.0440910899546112 0.9987693958981064 0.9862842906746282 1.1593108430732115 1.0278433622907162 1.0043879519347945 1.0 16.17071037175097 NQNYLVPS(ph)PVLR ddPTM_PC-9_Lapatinib_30min_R1 1 NQNYLVPSPVLR 12 0 J3KR59;J3KR68;Q9UID6;C9J3R1;C9IZP0 J3KR59 ZNF639 Zinc finger protein 639 1 NQNYLVPS(1)PVLR 104.17 0.0019420000000000001 10257000.0 40218.0 48980.0 41751.0 49805.0 60622.0 58268.0 55719.0 54240.0 57152.0 49586.0 True False 39644.483944922096 48866.58981932224 38318.39394352065 53467.825844609535 57056.33314743772 55776.01346934214 58603.85718483913 56760.18841285505 50714.93992275936 58156.874030808154 0.6816818236124716 0.8402547529194149 0.6588798758891644 0.9193724170299348 0.9810763404720234 0.9590614075955188 1.007685818082213 0.9759841696922497 0.8720368962041102 1.0 15.827662105109368 -5.883745307011223 5.545481978974058 0.9650077177108316 0.739538869451697 0.7788524304240151 0.056992925820747206 0.09162115887156762 4.083689883659954 0.015440783116299716 0.02326749049543646 1.3069371196834334e-06 5.883745307011223 -0.2254688482591346 NQPTVY(ph)IAASPPNTDELMSR ddPTM_PC-9_Lapatinib_30min_R1 1 NQPTVYIAASPPNTDELMSR 20 0 A0A1B0GV57;Q9NYJ8;Q9NYJ8-2 A0A1B0GV57 TAB2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 1 NQPT(0.007)VY(0.55)IAAS(0.404)PPNT(0.039)DELMSR 76.311 0.0022791 10022000.0 16722.0 11746.0 16032.0 15423.0 17412.0 15441.0 14421.0 12213.0 18466.0 18122.0 True False 16483.54121356077 11718.80285867209 14713.910845309643 16557.25886961977 16387.86039330911 14780.624424729056 15167.648817505076 12780.46056574851 16386.164624399404 21254.36355395285 0.7755368054996494 0.5513598574205553 0.6922771791288559 0.7790051594624426 0.7710351030605819 0.6954159971532142 0.7136251706151051 0.6013099631662046 0.7709553185539603 1.0 14.375471438747509 -8.546070410280723 21.245269690143065 1.0000000034850935 0.697302469505185 0.6280275055462555 0.07002963109933738 474.6273574498971 434794.0061407116 0.06889405542821594 0.017788368606735872 2.8439999846865245e-09 8.546070410280723 -0.3026975339799085 NQPTVYIAAS(ph)PPNTDELMSR ddPTM_PC-9_AZD4547_30min_R2 1 NQPTVYIAASPPNTDELMSR 20 0 A0A1B0GV57;Q9NYJ8;Q9NYJ8-2 A0A1B0GV57 TAB2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 1 NQPTVY(0.039)IAAS(0.893)PPNT(0.068)DELMSR 85.177 0.00068558 18497000.0 26666.0 20297.0 33688.0 40012.0 37163.0 35979.0 23650.0 34686.0 28684.0 33158.0 True False 35145.23331274364 26857.608320531937 33241.27510865182 30787.85157923765 32003.558930074178 33729.22744233254 25754.804183879216 29326.07570498614 30200.17768045339 31997.148512509717 1.0983864171209863 0.8393750558751069 1.0388824209024654 0.9622061030594874 1.0002003434012863 1.0541322902303512 0.8049093554011548 0.9165215360837767 0.9438396571071396 1.0 14.965655721844533 -7.241824765495962 24.983642093071666 0.9093610763370545 0.9918278048156715 0.20371112489335863 0.07874372426470698 1279.4620258471136 1629686.1587932827 0.028802459243257545 0.022278172125669647 5.730271964399344e-08 7.241824765495962 0.08246672847861691 NQPTVYIAAS(ph)PPNTDELMSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NQPTVYIAASPPNTDELMSR 20 0 A0A1B0GV57;Q9NYJ8;Q9NYJ8-2 A0A1B0GV57 TAB2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 1 NQPT(0.102)VYIAAS(0.704)PPNT(0.194)DELMSR;NQPTVYIAAS(0.641)PPNT(0.358)DELMSR;NQPTVY(0.004)IAAS(0.925)PPNT(0.071)DELMSR 118.44 1.2965e-05 19946800.0 84125.8 82554.4 74987.8 109449.0 123576.0 117891.0 129443.0 145996.0 115024.1 100478.6 True False 98366.63637971217 90749.85524897724 76775.79354481533 103316.9273684458 99362.16989773833 111708.58842475548 117181.22195383563 142163.7596955484 116706.10985828225 118694.5747918403 0.8287374258867509 0.7645661598950845 0.6468349010850772 0.8704435527035423 0.8371247807407708 0.9411431703653141 0.9872500251956864 1.1977275283631705 0.9832472129661755 1.0 16.856894469233154 -6.843047591459714 1.2164089560126798 1.067428215203415 0.7613297778408322 0.7132380865920636 0.07702505823778677 0.2331792748116833 0.7231727299941481 0.04018962459918462 0.03355137096034492 1.4353321361801593e-07 6.843047591459714 -0.3060984373625827 NQPTVYIAASPPNT(ph)DELMSR ddPTM_PC-9_AZD4547_30min_R2 1 NQPTVYIAASPPNTDELMSR 20 0 A0A1B0GV57;Q9NYJ8;Q9NYJ8-2 A0A1B0GV57 TAB2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 1 NQPTVYIAAS(0.234)PPNT(0.765)DELMS(0.001)R 126.04 3.8711e-06 0.0 20256.0 17691.0 25674.0 37037.0 27470.0 27367.0 22729.0 27291.0 19832.0 25985.0 True False 26696.986649026294 23409.26978363947 25333.545984906403 28498.691865945857 23656.2646667152 25655.737163743142 24751.83696809264 23073.80303479146 20880.279032169572 25075.273059218434 1.0646738157537896 0.9335599149152041 1.0102999048137193 1.1365256840331344 0.9434100522394286 1.0231488647463127 0.987101393059132 0.9201815262509705 0.8327039543241722 1.0 14.61397779081703 -7.700853303149555 3.1252089609848572 0.9044815464629692 1.0157073422337104 0.31521814560574546 0.06589219192945159 0.28457428089922054 5.5874715713358984 0.03673687188995127 0.0181440210663929 1.9913458661485862e-08 7.700853303149555 0.11122579577074121 NQQGFS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 NQQGFSPK 8 0 D6RCT7;C9JKA9;Q9NS87-4;Q9NS87-2;Q9NS87 D6RCT7 KIF15 Kinesin-like protein;Kinesin-like protein KIF15 1 NQQGFS(1)PK 68.847 0.042479 2423500.0 25474.0 32440.0 32680.0 31596.0 35632.0 36186.0 32186.0 37206.0 32910.0 37305.0 True False 33574.20210788386 42925.595601224595 32246.641847267347 24312.030353333816 30685.111853090508 33923.2836996094 35050.49164745608 31456.66760882529 34649.55541290339 35998.96330475826 0.9326435826402284 1.192411993585126 0.8957658467627333 0.6753536247006399 0.8523887644574092 0.9423405727665912 0.9736528063524315 0.8738214859833872 0.9625153680001527 1.0 15.13566774008719 -5.3670678684862665 9.282261178647039 0.8868772964051325 1.062124258503519 0.2833145012491457 0.10439940124523313 0.4002389432949449 32.07260699994581 0.027949126961967923 0.058289749302090514 4.294693070786365e-06 5.3670678684862665 0.17524696209838664 NQQGFS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NQQGFSPK 8 0 D6RCT7;C9JKA9;Q9NS87-4;Q9NS87-2;Q9NS87 D6RCT7 KIF15 Kinesin-like protein;Kinesin-like protein KIF15 1 NQQGFS(1)PK;NQQGFS(1)PK 71.03 0.036522000000000006 23302000.0 97235.0 137784.0 89005.0 106905.0 113748.0 74344.0 104531.0 88056.0 75178.0 71039.0 True False 113694.9650212097 151462.28493726696 91127.21675334239 100915.45944068627 91459.89594685032 70445.26976486781 94629.0669410966 85744.62330304422 76277.33602719691 83917.8083555856 1.354837158514068 1.8048884724857757 1.0859103513190944 1.2025511797576551 1.0898746969094637 0.8394555475801931 1.1276398751993628 1.021769097444941 0.9089529090653363 1.0 16.356689379726113 -5.346038363249182 6.524946177146718 1.0368253065199724 1.5773137688561787 0.7062697566779021 0.14079667558916734 0.11283655880156557 7.180449176011429 0.03619067076281762 0.07645766661208213 4.507768835664073e-06 5.346038363249182 0.5404884623362063 NQS(ph)FCPTVNLDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NQSFCPTVNLDK 12 0 E9PLL6;P46776;E9PJD9 E9PLL6 RPL27A 60S ribosomal protein L27a 1 NQS(0.933)FCPT(0.067)VNLDK 139.77 7.3423e-05 3477800.0 27145.0 42915.0 34614.0 36435.0 33763.0 34284.0 27331.0 24059.0 25112.0 22180.0 True False 31740.112361811516 47175.31758464557 35439.329034326016 34393.665073863776 27147.38251972345 32486.086686467348 24742.00982069545 23427.476742617637 25479.21549276349 26201.05842321662 1.2114057321320566 1.800511903856669 1.352591504583014 1.3126822786436647 1.0361177812446043 1.2398768844269894 0.9443133716602718 0.8941423802123457 0.9724498560785809 1.0 14.67733747188787 -6.223068206390914 0.9331604755975387 0.9595153308532809 1.5245414684817284 0.6224497209072732 0.15908377496386095 0.35943141350097674 0.6625989158663218 0.07387627795976019 0.12392937857754191 5.983176212890864e-07 6.223068206390914 0.5650261376284476 NQS(ph)FCPTVNLDK ddPTM_PC-9_Lapatinib_30min_R1 1 NQSFCPTVNLDK 12 0 E9PLL6;P46776;E9PJD9 E9PLL6 RPL27A 60S ribosomal protein L27a 1 NQS(0.927)FCPT(0.073)VNLDK 98.421 0.010818000000000001 0.0 14775.0 21516.0 23448.0 14701.0 23853.0 12691.0 17971.0 19669.0 16026.0 17494.0 True False 14564.305790596838 21466.181023939105 21520.19595189748 15782.16058109837 22450.013436802335 12148.235514165945 18901.45044722167 20582.89354521471 14220.983118738486 20517.814590710248 0.7098370894330553 1.0462216104466722 1.0488541972516447 0.7691930595885188 1.0941717665665485 0.592082332182992 0.9212214275383689 1.0031718268150218 0.6931041829950667 1.0 14.32458945323079 NQS(ph)LLASSEWPELR ddPTM_PC-9_AZD4547_30min_R2 1 NQSLLASSEWPELR 14 0 Q9UKK3 Q9UKK3 PARP4 Poly [ADP-ribose] polymerase 4 1 NQS(0.848)LLAS(0.08)S(0.072)EWPELR 130.47 1.9376e-05 1741400.0 3005.6 918.19 1139.4 5376.5 3138.7 2431.5 1610.1 3956.9 3249.7 3746.5 True False 3961.3182796363267 1214.9769613159194 1124.290811529266 4137.030991096953 2702.945682905679 2279.4579206212416 1753.3957808229998 3345.4520255163366 3421.472507605961 3615.336175345851 1.0956984599799708 0.3360619600471018 0.3109782208349446 1.1443004994414372 0.7476332910167363 0.6304968086137062 0.4849883097400385 0.9253501924191886 0.946377416002996 1.0 11.819914088395773 -7.884749270101157 7.773923965968487 0.9603051756804931 0.670383077706698 0.1915965934763989 0.26273618780762137 0.40223913409612894 25.47711080669092 0.14792707160522459 0.07070927708189592 1.3039193489431523e-08 7.884749270101157 -0.2899220979737951 NQS(ph)LLASSEWPELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NQSLLASSEWPELR 14 0 Q9UKK3 Q9UKK3 PARP4 Poly [ADP-ribose] polymerase 4 1 NQS(0.933)LLAS(0.016)S(0.051)EWPELR;NQS(1)LLASSEWPELR 128.71 0.00050499 1119300.0 8192.2 9497.6 8414.8 10639.9 11440.2 8100.3 10310.599999999999 11956.6 10171.4 8550.5 True False 9578.97765667461 10440.458960548283 8615.440745306714 10043.780898021216 9198.574934162849 7675.506008236827 9333.905325720338 11642.751919064878 10320.13748260172 10100.637964279242 0.9483537268190905 1.0336435181095307 0.8529600581443563 0.9943709430573494 0.9106924697918561 0.7599030908127924 0.9240906721664074 1.152674906301889 1.02173125292667 1.0 13.302158797163658 -7.689517082173946 9.5609077309475 1.0651604748839754 0.915987763474807 0.39482705737338697 0.07952071367423925 0.32968718715001594 40.91875393737162 0.038742164215013815 0.022302483990566797 2.0440095370689272e-08 7.689517082173946 -0.14917271140916832 NQS(ph)LLASSEWPELR ddPTM_PC-9_Lapatinib_30min_R1 2 NQSLLASSEWPELR 14 0 Q9UKK3 Q9UKK3 PARP4 Poly [ADP-ribose] polymerase 4 1 NQS(0.999)LLAS(0.001)S(0.001)EWPELR;NQS(0.999)LLASSEWPELR 128.06 2.6849e-05 3417400.0 13282.9 12338.7 12715.0 13806.5 12320.8 12994.5 11265.9 10785.7 12423.5 10212.1 True False 13093.483410214474 12310.130498237473 11669.621781319373 14821.876067133853 11596.114767624791 12438.755526658992 11849.193177527948 11286.84299713368 11024.234604745256 11977.24787823209 1.0931963288503925 1.0277929139807132 0.9743157944095147 1.2375026565219294 0.9681785737022288 1.0385320278179817 0.9893085037559527 0.9423569681351273 0.920431364268675 1.0 13.548008824524443 -7.143972839704029 1.3584209042842554 0.949857736914351 1.0659245371591861 0.30689489743527765 0.07215636614421778 0.5451389053029891 1.9975165355648965 0.04149713327379672 0.026762319600326805 7.178391827351867e-08 7.143972839704029 0.11606680024483507 NQS(ph)LVEENEK ddPTM_PC-9_AZD4547_30min_R2 2 NQSLVEENEK 10 0 O95239;O95239-2;Q2VIQ3 O95239 KIF4A;KIF4B Chromosome-associated kinesin KIF4A;Chromosome-associated kinesin KIF4B 1 NQS(1)LVEENEK;NQS(1)LVEENEK 133.04 0.00012647 55774000.0 171437.0 159136.0 174032.0 234000.0 198595.0 224275.0 168722.0 197819.0 191701.0 203180.0 True False 225950.39988887808 210573.59992590858 171724.22196951113 180054.91526396116 171023.5122492283 210251.04879594056 183737.9311421765 167250.61897839606 201833.92349465186 196066.7300431793 1.1524158118979062 1.0739894518541442 0.8758457997014216 0.9183348711140747 0.8722719668531435 1.0723443429165034 0.9371193730915609 0.8530290628173524 1.0294144419616855 1.0 17.580985224276738 -5.068132236282243 4.333117991772103 0.9407389372067843 1.138807778445909 0.5081789980714506 0.06803822121576696 0.1546133945200531 5.53470243228558 0.017391547104158207 0.05556929460693492 8.548063972798687e-06 5.068132236282243 0.19806884123912472 NQS(ph)LVEENEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NQSLVEENEK 10 0 O95239;O95239-2;Q2VIQ3 O95239 KIF4A;KIF4B Chromosome-associated kinesin KIF4A;Chromosome-associated kinesin KIF4B 1 NQS(1)LVEENEK;NQS(1)LVEENEK 113.52 0.0012948 37041000.0 96373.0 93241.0 94902.0 108963.0 111933.0 91285.0 104925.0 103477.0 97026.0 73682.0 True False 112687.045446486 102497.35027169835 97164.82359783941 102858.15637281234 90000.53216776357 86497.85390194171 94985.74440878365 100760.838392944 98444.82169484186 87039.96333360914 1.294658696196551 1.1775895387138862 1.1163242707883898 1.181734831143883 1.0340139025887118 0.9937717180602476 1.0912888835295083 1.1576387964083248 1.131030137472828 1.0 16.40939032838918 -3.852496012752487 0.727702760128128 1.0801501054013605 1.9433708791443596 0.5774739320438927 0.057293505506309315 7.680518637967982 1.133681108509989 0.02412711332225685 7.436766820544214 0.0001404442577673319 3.852496012752487 0.8632207737429991 NQS(ph)LVEENEK ddPTM_PC-9_Lapatinib_30min_R1 3 NQSLVEENEK 10 0 O95239;O95239-2;Q2VIQ3 O95239 KIF4A;KIF4B Chromosome-associated kinesin KIF4A;Chromosome-associated kinesin KIF4B 1 NQS(1)LVEENEK;NQS(1)LVEENEK;NQS(1)LVEENEK 138.31 0.00011894 57063600.0 175819.0 212622.0 203206.0 210064.0 232186.0 206462.0 193294.0 188087.0 204653.0 155916.0 True False 173311.78881874407 212129.68682245698 186499.18707784385 225512.80731296184 218529.27597523923 197632.1015464289 203301.81752519423 196826.208665352 181602.82404837068 182865.87285498946 0.9477535972837224 1.160028842509468 1.0198687385794263 1.2332142886594861 1.195024924899631 1.080748958025366 1.1117537370486303 1.0763419417325228 0.993093031592503 1.0 17.480426333247877 -8.123288582845761 2.5415298112561135 0.9933687316706158 1.1129431833465548 0.23482784653393596 0.07782646969953619 0.4223681119197598 4.8961045025042536 0.06671612266560124 0.020963771997425395 7.528551353700352e-09 8.123288582845761 0.11957445167593905 NQS(ph)PPVGYMSQPK ddPTM_PC-9_AZD4547_30min_R2 2 NQSPPVGYMSQPK 13 0 Q9H7U1-3 Q9H7U1-3 CCSER2 Serine-rich coiled-coil domain-containing protein 2 1 NQS(0.998)PPVGY(0.002)MSQPK;NQS(0.991)PPVGY(0.007)MS(0.002)QPK 92.265 0.004142 15867500.0 74920.0 68256.0 72405.0 105558.0 86533.0 86484.0 77517.0 95939.0 72978.0 91441.0 True False 98743.00156719219 90318.41718117092 71444.86239141347 81223.23395484286 74519.38661830599 81076.1418083518 84415.86282967313 81113.83200889897 76835.46809246026 88239.6784224742 1.119031747763519 1.023557868703285 0.8096682090039986 0.9204842470749045 0.8445110856084702 0.9188172855773022 0.9566655765165712 0.9192444199597138 0.8707587047698335 1.0 16.429139912782155 -5.028449464659041 4.851697121365107 0.9029185575555205 1.1021447006650247 0.643282057033765 0.051738415527458476 0.09826162817801888 6.087848725904537 0.012841014430932307 0.04244500921886196 9.36592197222704e-06 5.028449464659041 0.19922614310950415 NQS(ph)PPVGYMSQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NQSPPVGYMSQPK 13 0 Q9H7U1-3 Q9H7U1-3 CCSER2 Serine-rich coiled-coil domain-containing protein 2 1 NQS(0.71)PPVGY(0.009)MS(0.281)QPK 75.998 0.015615 4394400.0 20685.0 17772.0 18008.0 20653.0 21084.0 19335.0 19423.0 21226.0 16913.0 15251.0 True False 24186.561952627406 19536.28670894374 18437.37901572031 19495.879367929432 16952.741552760395 18321.038562677804 17583.112829657442 20668.839990806016 17160.320628747555 18015.885573150434 1.342513075719869 1.084392250917668 1.0233956549545387 1.0821493780458216 0.9409885228193017 1.0169379955422313 0.975978269747785 1.1472563980762263 0.9525105251735196 1.0 14.136981948915672 -4.639755633916381 2.0304247005681986 1.0197798416719228 1.5322794631101972 0.7393026169261936 0.057759300196090685 0.5864398625767517 1.9133878335388546 0.01485667077445794 0.6378437447212503 2.2921570264636327e-05 4.639755633916381 0.5124996214382744 NQS(ph)PPVGYMSQPK ddPTM_PC-9_Lapatinib_30min_R1 4 NQSPPVGYMSQPK 13 0 Q9H7U1-3 Q9H7U1-3 CCSER2 Serine-rich coiled-coil domain-containing protein 2 1 NQS(0.52)PPVGY(0.241)MS(0.24)QPK;NQS(0.768)PPVGY(0.204)MS(0.028)QPK;NQS(0.848)PPVGY(0.037)MS(0.114)QPK;NQS(0.917)PPVGY(0.012)MS(0.071)QPK 88.311 0.0058698 25191500.0 181127.0 144844.0 157217.0 158962.0 165481.0 156759.0 127387.0 128445.0 152055.0 120772.0 True False 178544.09576537588 144508.6226171891 144291.22513517042 170652.59576168706 155747.73292816378 150054.7829930768 133982.47555062195 134413.02361152624 134928.96468986513 141647.2792814256 1.2604837641155358 1.0202004821432438 1.0186657016439533 1.2047714338560187 1.0995462370916655 1.0593552079101154 0.9458880977475382 0.9489276765032224 0.9525701120018515 1.0 17.11194336556411 -7.07653173270597 2.764402837619475 0.9570764676815577 1.1136771991431071 0.5260983424134784 0.07077744536203334 0.2363097851065185 3.538079065972213 0.029920634305968096 0.022893205845854598 8.38432814398771e-08 7.07653173270597 0.1566007314615494 NQS(ph)PVLEPVGR ddPTM_PC-9_AZD4547_30min_R2 4 NQSPVLEPVGR 11 0 B4DG22;B1AXG1;B7ZB17;P51812;A0A2R8Y603 B4DG22 RPS6KA3 Ribosomal protein S6 kinase alpha-3 1 NQS(1)PVLEPVGR;NQS(1)PVLEPVGR;NQS(1)PVLEPVGR;NQS(1)PVLEPVGR 125.84 0.00044086 58360000.0 76934.0 82702.0 128903.0 179738.0 146012.0 124202.0 109675.0 156422.0 101025.0 113873.0 True False 101397.41167339019 109433.8041742442 127193.66199627602 138302.181024418 125740.75415057957 116435.62930577823 119435.86253137211 132250.5741199718 106364.97525337481 109886.34093024347 0.9227480942127092 0.9958817742754166 1.1575020236320304 1.2585930139598795 1.1442801087571073 1.0596005683699332 1.0869036271504458 1.2035215023123327 0.967954473257927 1.0 16.745652542280936 -5.0806636764490865 3.8568553432341037 1.1205210216179675 0.934439269941651 0.34578310709831706 0.0842560427474861 0.22691031605960857 6.1810410352835055 0.021846789091734528 0.07335323542170556 8.304936641322154e-06 5.0806636764490865 -0.18608175167631646 NQS(ph)PVLEPVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NQSPVLEPVGR 11 0 B4DG22;B1AXG1;B7ZB17;P51812;A0A2R8Y603 B4DG22 RPS6KA3 Ribosomal protein S6 kinase alpha-3 1 NQS(1)PVLEPVGR;NQS(1)PVLEPVGR;NQS(1)PVLEPVGR;NQS(1)PVLEPVGR 123.95 0.00053626 52111000.0 100785.0 100454.0 116415.0 132885.0 143352.0 133262.0 139070.0 122527.0 125359.0 111206.0 True False 117845.90990551375 110426.40924264224 119190.7751063461 125439.88426898276 115263.20466094231 126273.50612565651 125896.2828203914 119310.79607808769 127192.13821907192 131366.7674937883 0.897075509687685 0.8405962280213964 0.9073129938436071 0.9548829331962835 0.8774152463361219 0.9612286922689741 0.9583571646180943 0.9082266265227948 0.9682215726674268 1.0 17.00324083049462 -1.5228787452818007 0.10949711102969177 1.0302320523109216 0.537045843263979 0.5494416663129089 0.031137848968949097 84.54846243955053 0.6492880984226378 0.29364144720374746 6.296219217490341 0.02999999999989893 1.5228787452818007 -0.49318620904694266 NQS(ph)PVLEPVGR ddPTM_PC-9_Lapatinib_30min_R1 4 NQSPVLEPVGR 11 0 B4DG22;B1AXG1;B7ZB17;P51812;A0A2R8Y603 B4DG22 RPS6KA3 Ribosomal protein S6 kinase alpha-3 1 NQS(1)PVLEPVGR;NQS(1)PVLEPVGR;NQS(1)PVLEPVGR;NQS(1)PVLEPVGR 120.6 0.00085019 56767000.0 214151.0 185253.0 234442.0 167443.0 200722.0 229176.0 178113.0 196124.0 259647.0 147719.0 True False 211097.1674695162 184824.05806041023 215167.08373229086 179757.31679347364 188915.92659463538 219374.67671534882 187334.81962639754 205236.63702586238 230402.8206558776 173252.03232680482 1.2184397760559842 1.0667930158058818 1.241931080649154 1.0375480990283446 1.0904110275502212 1.2662170467446119 1.081284976057472 1.1846131573148018 1.3298708105268826 1.0 17.40251275038144 NQS(ph)SEDILR ddPTM_PC-9_AZD4547_30min_R2 2 NQSSEDILR 9 0 Q13625-2;Q13625;Q13625-3;H0Y847 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 NQS(0.905)S(0.095)EDILR;NQS(0.764)S(0.236)EDILR 85.973 0.012022 44084000.0 58196.0 75672.0 75350.0 103627.0 111225.0 92480.0 84600.0 91207.0 93134.0 99058.0 True False 76701.11744800226 100131.49415338675 74350.80976718462 79737.39617119022 95783.32863325084 86697.21098048627 92129.23610808396 77113.05387835625 98056.87310317052 95590.00957090875 0.8023967964048095 1.0475100337667518 0.7778094185881541 0.8341603534628894 1.0020223772673513 0.906969372318916 0.9637956573248632 0.8067062052248642 1.0258067087066443 1.0 16.54457222478829 -6.248252276496631 24.84239473588861 0.9396686127351698 0.872210664711951 0.1711834162501482 0.08957749016809571 1636.487655509292 3082879.6235937574 0.02581792019917135 0.03311521562614386 5.646089049412942e-07 6.248252276496631 -0.0674579480232188 NQS(ph)SEDILR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NQSSEDILR 9 0 Q13625-2;Q13625;Q13625-3;H0Y847 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 NQS(0.908)S(0.092)EDILR 72.73100000000001 0.031497000000000004 15902000.0 38993.0 62457.0 60146.0 75354.0 88425.0 88362.0 78373.0 77383.0 79344.0 57882.0 True False 45593.74475314478 68657.3181960668 61580.10874497525 71132.15968096405 71098.75601417362 83728.14116758923 70948.94206861685 75351.77824406588 80504.25589589952 68375.54840634002 0.6668135878368644 1.0041209145124845 0.9006159391807573 1.0403157464747796 1.0398272141328975 1.2245333766101927 1.0376361685171978 1.1020281372555543 1.1773836959592836 1.0 16.061192878641982 -4.0908751473181555 0.654845706138555 1.1060286312191858 3.4034738429249526e-13 0.6908631132981913 0.08135297680198794 4.116773492887851 0.6916616609176789 0.03426798379795485 4.176603960070128 8.11194229635956e-05 4.0908751473181555 -1.1060286312188454 NQS(ph)SEDILR ddPTM_PC-9_Lapatinib_30min_R1 1 NQSSEDILR 9 0 Q13625-2;Q13625;Q13625-3;H0Y847 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 NQS(0.786)S(0.214)EDILR 101.72 0.0034080999999999994 15079000.0 43024.0 31088.0 34257.0 39060.0 41718.0 31727.0 35128.0 35465.0 34904.0 33272.0 True False 42410.46987036469 31016.017646041033 31440.521695844105 41932.602700340285 39264.22926074372 30370.110169249307 36946.75595737594 37112.83337134782 30972.743964585527 39023.02086784675 1.0868064267497304 0.7948133423877715 0.8056916403862958 1.0745606508103758 1.006181181967276 0.7782613824823833 0.9467938446512848 0.9510497277243638 0.7937044153879358 1.0 15.252037844384349 NQSFCPTVNLDK ddPTM_PC-9_Lapatinib_30min_R1 2 NQSFCPTVNLDK 12 0 E9PLL6;P46776;E9PJD9 E9PLL6 RPL27A 60S ribosomal protein L27a 0 ; 156.69 1.6419e-11 0.0 77857.0 59838.0 67791.0 62589.0 72947.0 60802.0 62753.0 57657.0 60269.0 68477.0 False True 76746.74490277475 59699.44878743577 62217.48566082746 67192.00385078331 68656.40087931998 58201.64019638467 66002.04328721279 60335.95470722683 53480.87055929422 80313.158210133 0.9555936612774334 0.7433333480827252 0.7746860794347091 0.8366250979071296 0.8548586857920087 0.7246837441519197 0.8218085897521759 0.7512586486682867 0.6659042148406836 1.0 16.29334875246446 -6.740851370712895 24.99715349039731 0.7790020176452749 0.8249963877412538 0.02872292224897821 0.0971938348783856 840.5571766007092 1020569.4321383489 0.030677594969056275 0.030643381259630335 1.8161370958994556e-07 6.740851370712895 0.045994370095978954 NQSHS(ph)SPSVSPS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 NQSHSSPSVSPSR 13 0 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;Q7Z6E9-4 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 2 NQSHS(0.579)S(0.408)PS(0.012)VS(0.198)PS(0.802)R 133.25 0.00074704 0.0 6890.5 5628.5 6714.5 5714.4 7457.8 7244.9 4814.3 4946.0 7740.6 5470.5 True False 6792.240206437055 5615.467554064008 6162.459728719541 6134.6560386795845 7019.146866598938 6935.052515686772 5063.560897449187 5175.809216260714 6868.77211586841 6416.068636016947 1.058629605099367 0.8752193707126633 0.9604728500138296 0.9561394035348005 1.0939949780456804 1.080888143365001 0.7891999267315526 0.8066948017366944 1.070557767619596 1.0 12.647473859795262 NQSHSSPS(ph)VSPS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 NQSHSSPSVSPSR 13 0 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;Q7Z6E9-4 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 2 NQSHS(0.133)S(0.095)PS(0.772)VS(0.057)PS(0.943)R 131.86 0.0010857000000000002 0.0 9633.2 9367.6 9810.3 8461.1 10961.0 8745.5 8775.1 8524.5 8940.6 7126.7 True False 9495.828801487476 9345.909897743632 9003.73500285312 9083.357519402181 10316.29553015513 8371.475351756222 9229.431741105947 8920.579390217235 7933.6154793082 8358.54059926916 1.1360630110856622 1.1181269967822858 1.077189839054006 1.0867157264506675 1.2342220998552247 1.001547489341404 1.104191770261059 1.0672412587189226 0.9491627617388 1.0 13.029035354480943 -8.088228279118434 3.3532753367364734 0.9753262008718918 1.1069622238313022 0.4703908044963825 0.05579947327601821 0.2240318812455983 4.587789674317297 0.04282920590312657 0.014577540256988266 8.161532622425158e-09 8.088228279118434 0.13163602295941035 NQSLGQS(ph)APSLTAGLK ddPTM_PC-9_AZD4547_30min_R2 2 NQSLGQSAPSLTAGLK 16 0 Q6P0Q8;Q6P0Q8-2 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 NQSLGQS(0.989)APS(0.011)LTAGLK;NQS(0.131)LGQS(0.586)APS(0.277)LT(0.006)AGLK 245.67 5.8786e-47 73438000.0 233878.0 192998.0 228305.0 351010.0 284980.0 288190.0 255730.0 266630.0 259251.0 287790.0 True False 308246.33903539507 255380.82921840774 225277.526528163 270090.0675504402 245415.44611286809 270169.4337420661 278489.4745853467 225428.46004787073 272954.47858859383 277714.55969645834 1.1099394261946796 0.9195802679468396 0.8111837088209961 0.9725455800576257 0.8836967222068114 0.9728313633875045 1.0027903286371997 0.8117271931808824 0.9828598071593104 1.0 18.083243289516687 -4.760853840107919 24.713088564805204 0.9227006065771557 1.10993966218548 0.3824936227548468 0.06876660620543391 12.312556449717206 519150.17377148726 0.016432892504685333 0.09482358722836727 1.7343876000401297e-05 4.760853840107919 0.18723905560832432 NQSLGQS(ph)APSLTAGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NQSLGQSAPSLTAGLK 16 0 Q6P0Q8;Q6P0Q8-2 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 NQS(0.001)LGQS(0.764)APS(0.233)LT(0.002)AGLK;NQSLGQS(0.996)APS(0.004)LTAGLK;NQS(0.002)LGQS(0.976)APS(0.022)LTAGLK;NQSLGQS(0.917)APS(0.082)LT(0.001)AGLK 189.56 3.0586e-08 71578000.0 244557.0 237846.0 197182.0 262837.0 285460.0 261908.0 262431.0 249239.0 239839.0 216514.0 True False 285955.66987907665 261457.7790105461 201883.56669689927 248111.0950190516 229526.16219175552 248173.08341731672 237571.635844094 242696.7403405489 243346.19164418997 255766.27427611963 1.1180350915631871 1.0222527569380866 0.789328332159033 0.9700696298652587 0.897405894664455 0.9703119933216626 0.9288622454875224 0.9489004796564336 0.9514397171125024 1.0 17.964466515269443 -5.009147115955016 11.520858926998534 0.9298632703804524 1.0942781668552448 0.531850239182101 0.05510794368570084 0.2629007576880843 337.708868364453 0.013195749065954636 0.0413792771768972 9.791582423014166e-06 5.009147115955016 0.16441489647479246 NQSLGQSAPS(ph)LTAGLK ddPTM_PC-9_Lapatinib_30min_R1 1 NQSLGQSAPSLTAGLK 16 0 Q6P0Q8;Q6P0Q8-2 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 NQSLGQS(0.296)APS(0.704)LTAGLK 204.71 6.7769e-17 30229000.0 127470.0 105090.0 101260.0 99473.0 105390.0 95370.0 92808.0 89166.0 103410.0 81958.0 True False 125652.25442486508 104846.67056171042 92934.79367490353 106788.57625220055 99191.1674047121 91291.2474183284 97613.14412696831 93308.97787648687 91762.87684442449 96124.33109782952 1.3071846949653552 1.0907401837210584 0.9668186255602667 1.1109422040452757 1.03190489100789 0.9497204961085004 1.0154884097723766 0.9707113361498728 0.9546269482076687 1.0 16.552614033350032 NQSLGQSAPSLT(ph)AGLK ddPTM_PC-9_Lapatinib_30min_R1 1 NQSLGQSAPSLTAGLK 16 0 Q6P0Q8;Q6P0Q8-2 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 NQSLGQS(0.144)APS(0.03)LT(0.826)AGLK 210.2 5.490699999999999e-17 25516000.0 113470.0 112110.0 109270.0 88217.0 112640.0 106120.0 96522.0 95626.0 105160.0 73852.0 True False 111851.89699215034 111850.41618301783 100286.24239439792 94704.7724632851 106014.73665876043 101581.49497780247 101519.43687422691 100069.13305987619 93315.77341610756 86617.21979839547 1.2913355710618448 1.2913184750486508 1.157809528264906 1.093371187434943 1.2239452721469628 1.1727632821076095 1.1720468182945247 1.1553029904768417 1.0773351261250732 1.0 16.4023662457042 -1.5228787504290995 0.050769328483644176 0.675907635033559 2.0833675580423097 0.687374924067758 0.04863657347531729 313.75029717718627 1.2060908106747097 7.7952740513383905 34.44902982394864 0.02999999964433613 1.5228787504290995 1.4074599230087506 NQSLLASS(ph)EWPELR ddPTM_PC-9_AZD4547_30min_R2 1 NQSLLASSEWPELR 14 0 Q9UKK3 Q9UKK3 PARP4 Poly [ADP-ribose] polymerase 4 1 NQS(0.236)LLAS(0.231)S(0.533)EWPELR 127.3 0.00060306 0.0 4166.8 3677.9 5909.0 5635.9 3516.4 5554.0 4604.1 6094.7 3973.2 5413.9 True False 5491.7557251758835 4866.709249745496 5830.64279912799 4336.630328787004 3028.20855748225 5206.707502007144 5013.85598067646 5152.904157273224 4183.215240551434 5224.361008862908 1.0511822815956537 0.9315415304358425 1.1160489846005186 0.8300786108444829 0.5796323325177991 0.9966209251570066 0.959707028700862 0.9863223748380977 0.8007132802374847 1.0 12.351038876741878 -5.7733736236288244 24.999893540077434 0.8742294209834163 1.0227860056489977 0.23253762848482518 0.12753056949031105 345.42418958877226 723595.4765325971 0.037768937889912764 0.0565196905336567 1.6851027074307204e-06 5.7733736236288244 0.14855658466558141 NQSPPVGYMS(ph)QPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NQSPPVGYMSQPK 13 0 Q9H7U1-3 Q9H7U1-3 CCSER2 Serine-rich coiled-coil domain-containing protein 2 1 NQS(0.086)PPVGY(0.249)MS(0.665)QPK 72.928 0.019777 9998600.0 39448.0 38698.0 32528.0 41699.0 47062.0 37956.0 48702.0 44359.0 41549.0 32618.0 True False 46125.76726648518 42539.681693827675 33303.59088312694 39362.74021998203 37840.538937393765 35965.520542280785 44088.593988054236 43194.623252245525 42156.57552201459 38531.38519605407 1.1970960045113777 1.1040267947123814 0.8643237380040388 1.0215760481928664 0.9820705574132577 0.9334084502615791 1.1442255128831773 1.121024407310148 1.0940840903464786 1.0 15.233746431094696 -7.276257538076588 24.914648645636095 1.0999188668812545 1.0127046285566494 0.12652334015929878 0.09169961459995715 1537.1270870216654 2584452.6606089664 0.040069080745078665 0.027139792585122755 5.293494448129092e-08 7.276257538076588 -0.08721423832460506 NQSPT(ph)EAEKPASSSLPSSPPPQLLTR ddPTM_PC-9_AZD4547_30min_R2 2 NQSPTEAEKPASSSLPSSPPPQLLTR 26 1 Q99567;I3L2W3 Q99567 NUP88 Nuclear pore complex protein Nup88 1 NQS(0.077)PT(0.913)EAEKPAS(0.007)S(0.002)S(0.001)LPSSPPPQLLTR;NQS(0.034)PT(0.944)EAEKPAS(0.001)S(0.006)S(0.006)LPS(0.004)S(0.004)PPPQLLTR 66.609 0.00038992 49299000.0 24743.6 24376.4 28968.2 42652.8 38268.0 32164.1 31587.1 34087.3 35360.5 29900.9 True False 32611.55010114766 32255.594593517 28584.06274051438 32819.855939190944 32955.14875376259 30152.873742403313 34398.29070767911 28819.891033228807 37229.58384010849 28854.078592125636 1.1302232367956275 1.1178868349765863 0.9906420213437367 1.1374425225329352 1.1421313852924815 1.0450125324962594 1.1921465659647335 0.9988151567970651 1.290271104004983 1.0 14.816487641184283 NQSPT(ph)EAEKPASSSLPSSPPPQLLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NQSPTEAEKPASSSLPSSPPPQLLTR 26 1 Q99567;I3L2W3 Q99567 NUP88 Nuclear pore complex protein Nup88 1 NQS(0.068)PT(0.775)EAEKPAS(0.097)S(0.041)S(0.018)LPS(0.001)S(0.001)PPPQLLTR;NQS(0.036)PT(0.738)EAEKPAS(0.081)S(0.081)S(0.036)LPS(0.014)S(0.014)PPPQLLT(0.001)R;NQS(0.024)PT(0.975)EAEKPAS(0.001)SSLPSSPPPQLLTR 86.073 8.5682e-07 80075900.0 69601.0 58890.0 68041.0 78585.0 88284.0 66268.0 81558.0 80736.8 65405.0 58574.6 True False 81383.07461758878 64736.210009548544 69663.35548692955 74182.13722600762 70985.38395199658 62792.78942185324 73832.23581121354 78617.54454771076 66361.4243908965 69193.71130372157 1.1761628778714115 0.9355793870543075 1.006787382471024 1.0720936314629756 1.0258935763744566 0.9074927220803075 1.0670367930855948 1.13619493833224 0.9590672785219899 1.0 16.07835330349225 NQSPT(ph)EAEKPASSSLPSSPPPQLLTR ddPTM_PC-9_Lapatinib_30min_R1 2 NQSPTEAEKPASSSLPSSPPPQLLTR 26 1 Q99567;I3L2W3 Q99567 NUP88 Nuclear pore complex protein Nup88 1 NQS(0.041)PT(0.955)EAEKPAS(0.003)S(0.001)SLPSSPPPQLLTR;NQS(0.01)PT(0.987)EAEKPAS(0.002)S(0.001)SLPSSPPPQLLTR 109.84 3.2189999999999994e-10 95991000.0 67139.0 64136.0 71483.0 78539.0 78675.0 82271.0 58986.0 71286.0 79612.0 66394.0 True False 66181.58554821517 63987.49703250407 65605.9436723595 84315.02005842351 74047.49118100124 78752.46111306807 62040.0064592854 74598.20780233739 70645.25820847426 77870.11443555598 0.8498971142900522 0.8217208552513309 0.8425047805298128 1.0827648150973403 0.9509102653532341 1.011331005276001 0.7967113816254718 0.9579825115587012 0.9072191394676723 1.0 16.24878212595963 -5.569235875132923 24.999925955338867 0.9524217358745135 0.834884364322229 0.3782932336923489 0.07031654719317722 127.91975335542118 68985.19464678425 0.01934981348260433 0.03351487860426498 2.696274627105424e-06 5.569235875132923 -0.1175373715522845 NQSPTEAEKPASS(ph)SLPSSPPPQLLTR ddPTM_PC-9_Lapatinib_30min_R1 1 NQSPTEAEKPASSSLPSSPPPQLLTR 26 1 Q99567;I3L2W3 Q99567 NUP88 Nuclear pore complex protein Nup88 1 NQSPTEAEKPASS(0.386)S(0.386)LPS(0.112)S(0.112)PPPQLLT(0.003)R 88.684 3.7351999999999997e-07 12754000.0 22919.0 27114.0 27447.0 20370.0 20089.0 23195.0 26440.0 23814.0 23114.0 18157.0 True False 22592.17085717016 27051.2191988792 25190.413608483883 21868.07775232799 18907.40451649362 22203.003920185878 27808.933828086425 24920.48537728118 20510.65791878954 21295.413257318287 1.0608937513530636 1.2702838339886595 1.1829032526441843 1.0268914478479494 0.8878627659407354 1.0426190678669123 1.305864952798215 1.1702278362086782 0.9631490908842043 1.0 14.378255106549638 -5.749067957796964 24.145930735552962 1.0665175080353695 1.1812527143175269 0.16029676223666067 0.11816389920136508 307.7815710966972 600704.3087953032 0.0350513663769098 0.060104945749409416 1.7820998851157646e-06 5.749067957796964 0.11473520628215739 NQSPTEAEKPASSSLPS(ph)SPPPQLLTR ddPTM_PC-9_AZD4547_30min_R2 4 NQSPTEAEKPASSSLPSSPPPQLLTR 26 1 Q99567;I3L2W3 Q99567 NUP88 Nuclear pore complex protein Nup88 1 NQSPTEAEKPASS(0.002)S(0.007)LPS(0.491)S(0.491)PPPQLLT(0.009)R;NQSPTEAEKPASS(0.001)S(0.011)LPS(0.494)S(0.494)PPPQLLTR;NQSPTEAEKPAS(0.001)S(0.01)S(0.013)LPS(0.488)S(0.488)PPPQLLT(0.002)R;NQSPT(0.001)EAEKPASS(0.051)S(0.051)LPS(0.449)S(0.449)PPPQLLTR 98.135 1.6186e-09 173254100.0 277806.0 249847.0 310529.0 427099.0 374808.0 353981.0 314332.0 354022.0 301742.0 347922.0 True False 366142.5292762348 330605.15672562155 306411.182563956 328637.9241637712 322772.37885701476 331846.51211163023 342306.93905822904 299316.034516248 317691.4661014978 335741.35667921486 1.090549382708508 0.9847019145797379 0.912640568307221 0.9788425453876073 0.9613721170651272 0.9883992707776362 1.0195554770015636 0.8915077888430362 0.9462387036370891 1.0 18.356990733846665 -4.786003777756765 3.9407885340311677 0.9612598277610301 1.1018458109569929 0.5207512521782 0.03667517186809858 0.1850077346818728 5.309711685306404 0.009374907650244069 0.0738572852506847 1.636802283467046e-05 4.786003777756765 0.14058598319596272 NQSPTEAEKPASSSLPS(ph)SPPPQLLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NQSPTEAEKPASSSLPSSPPPQLLTR 26 1 Q99567;I3L2W3 Q99567 NUP88 Nuclear pore complex protein Nup88 1 NQSPTEAEKPASS(0.004)S(0.011)LPS(0.492)S(0.492)PPPQLLT(0.001)R;NQSPT(0.005)EAEKPAS(0.022)S(0.218)S(0.084)LPS(0.336)S(0.336)PPPQLLTR;NQSPTEAEKPAS(0.002)S(0.011)S(0.011)LPS(0.433)S(0.433)PPPQLLT(0.112)R;NQSPTEAEKPAS(0.006)S(0.02)S(0.02)LPS(0.476)S(0.476)PPPQLLT(0.003)R 94.955 2.2306999999999998e-09 128967000.0 149328.0 149310.0 147408.0 178325.0 195060.0 163281.0 193663.0 171179.0 150667.0 137858.0 True False 174606.28103756122 164132.51004458664 150922.76576795327 168334.02838745026 156839.393249926 154718.25692022732 175317.83864129885 166685.73262914305 152870.21984103977 162850.56411667238 1.072187142762776 1.0078719157951201 0.9267561742053679 1.0336717548417538 0.9630878105989259 0.9500627631193297 1.0765565326239486 1.0235502316695877 0.9387147086056005 1.0 17.313189191695443 -8.249754592062407 24.627547513663423 0.9693573488993119 1.0039746636374511 0.08425052025122004 0.04860066499938446 1566.0669939032045 3300755.289329437 0.03401380690638588 0.012625969113970086 5.62659178694834e-09 8.249754592062407 0.03461731473813923 NQSPTEAEKPASSSLPS(ph)SPPPQLLTR ddPTM_PC-9_Lapatinib_30min_R1 3 NQSPTEAEKPASSSLPSSPPPQLLTR 26 1 Q99567;I3L2W3 Q99567 NUP88 Nuclear pore complex protein Nup88 1 NQS(0.006)PT(0.084)EAEKPAS(0.02)S(0.02)S(0.018)LPS(0.419)S(0.419)PPPQLLT(0.014)R;NQSPTEAEKPAS(0.002)S(0.057)S(0.057)LPS(0.442)S(0.442)PPPQLLTR;NQSPTEAEKPAS(0.029)S(0.099)S(0.143)LPS(0.362)S(0.362)PPPQLLT(0.006)R 78.736 2.2608e-05 129778000.0 141843.0 122065.0 150011.0 133286.0 158710.0 156569.0 139606.0 144893.0 148942.0 125855.0 True False 139820.2928091798 121782.36599215107 137677.67463920568 143088.29706906175 149374.98983586545 149872.90885016538 146834.1155825958 151625.25773790208 132166.5835312086 147608.86905875357 0.9472350387938164 0.8250342053882777 0.9327195277433166 0.9693746587280438 1.0119648689700949 1.0153381013339424 0.994751308094845 1.0272096704267129 0.8953837555560541 1.0 17.171419882574078 -5.666560617371783 2.786150124386222 0.9926542015710564 0.8848840211178464 0.4594464027506646 0.04438057853739209 0.20607224340582603 3.2147065656459617 0.012156699784347713 0.02336410428636173 2.1549608403447995e-06 5.666560617371783 -0.10777018045321007 NQSQS(ph)QDALVLEDVEK ddPTM_PC-9_AZD4547_30min_R2 2 NQSQSQDALVLEDVEK 16 0 Q92887 Q92887 ABCC2 Canalicular multispecific organic anion transporter 1 1 NQSQS(1)QDALVLEDVEK;NQS(0.086)QS(0.914)QDALVLEDVEK 214.66 5.9499999999999995e-22 9521800.0 21435.7 30012.0 35392.0 39808.0 32995.0 30781.0 49733.0 40268.0 41289.0 32396.0 True False 28251.806709741948 39712.79208335245 34922.678955278025 30630.880627469094 28414.21378515722 28856.259204047874 54159.140654412884 34045.50586658541 43471.45224683584 31261.825900574986 0.9037158226008265 1.2703286177094995 1.1171029826071581 0.9798173889422662 0.9089108830535265 0.923050985435791 1.7324368968933692 1.0890440620731376 1.3905602438287614 1.0 14.93211442342686 NQSQS(ph)QDALVLEDVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NQSQSQDALVLEDVEK 16 0 Q92887 Q92887 ABCC2 Canalicular multispecific organic anion transporter 1 1 NQS(0.028)QS(0.972)QDALVLEDVEK;NQS(0.028)QS(0.972)QDALVLEDVEK 106.44 0.0010194 9791900.0 22852.0 24546.0 27245.0 34606.0 53511.0 37617.0 36693.0 36119.0 39334.0 31746.0 True False 26720.392252426467 26982.76466113737 27894.624127237887 32667.13801416576 43025.90368192761 35644.29829905615 33217.17340568503 35170.91452124386 39909.18533738288 37501.298498802294 0.7125191212586907 0.7195154765640752 0.7438308870325857 0.8710935173407148 1.1473177037670244 0.9504817093251997 0.8857606199088256 0.9378585790133944 1.0642080923853205 1.0 15.194652929967294 -5.905718989883214 3.493352228118892 0.9882832929529085 0.723639818416075 0.7563519244393644 0.06895618768853673 0.12185102666582279 2.920184306458541 0.021229229821293532 0.03295638144062518 1.2424559783322774e-06 5.905718989883214 -0.26464347453683346 NQSQS(ph)QDALVLEDVEK ddPTM_PC-9_Lapatinib_30min_R1 2 NQSQSQDALVLEDVEK 16 0 Q92887 Q92887 ABCC2 Canalicular multispecific organic anion transporter 1 1 NQS(0.006)QS(0.994)QDALVLEDVEK;NQS(0.017)QS(0.983)QDALVLEDVEK 200.99 2.2036e-12 8915400.0 73358.0 73104.0 36918.0 37376.0 40487.0 29810.0 23131.4 23376.0 46263.0 18039.6 True False 72311.90146779025 72934.73217949655 33882.74454760114 40124.755722680966 38105.63426050459 28535.095790504034 24329.030709190545 24462.13429828355 41052.373769012724 21157.720823743937 3.417754779458064 3.447192293871589 1.6014364132065084 1.89645926690041 1.8010273685878824 1.3486847675237754 1.1498890127091408 1.1561800300735268 1.9403022712608207 1.0 14.36889660372252 -5.272489288384226 5.189468391360298 1.4936625182301226 3.455343205482892 0.8635000928292398 0.3095975001549305 0.056317474531034986 5.035536456507103 0.08556499906787088 0.20360111403783726 5.33962443278683e-06 5.272489288384226 1.9616806872527695 NQSQS(ph)QDALVLEDVEKK ddPTM_PC-9_AZD4547_30min_R2 1 NQSQSQDALVLEDVEKK 17 1 Q92887 Q92887 ABCC2 Canalicular multispecific organic anion transporter 1 1 NQS(0.232)QS(0.768)QDALVLEDVEKK 66.137 0.0094159 5284300.0 6971.4 7902.6 11058.0 9041.1 9908.6 12072.0 14583.0 9987.1 12279.0 5378.1 True False 9188.160185871935 10456.9609062342 10911.363694831158 6956.814078602564 8532.961924885856 11317.13593162229 15880.858748985649 8443.82317572701 12928.042871924674 5189.814355966238 1.7704217445291042 2.0149007631097295 2.1024574187875134 1.3404745529298123 1.6441747892342853 2.1806436907732647 3.060005167762683 1.6269990786895772 2.49104148726679 1.0 12.341467217750631 -6.773698245448624 24.468831576627437 2.1726921724160353 1.7819511534796675 0.05468669447442209 0.5415467176810118 407.9616809468957 814289.9499118555 0.18423456364888535 0.16370719297408867 1.6838436154081666e-07 6.773698245448624 -0.3907410189363678 NQT(ph)YSFSPSK ddPTM_PC-9_Lapatinib_30min_R1 1 NQTYSFSPSK 10 0 Q86YS7-3;Q86YS7;H0YFE9 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 NQT(0.359)YS(0.317)FS(0.317)PS(0.006)K 135.1 0.00027572 39781000.0 289350.0 261860.0 297820.0 286480.0 266960.0 257520.0 246050.0 230590.0 217030.0 168300.0 True False 285223.8159397084 261253.67925863067 273334.3892184451 307548.6948692647 251257.93766355404 246506.46990844034 258789.26506810365 241304.05321018107 192585.7959727823 197390.43075434671 1.444972863424523 1.3235377128477015 1.3847398183076616 1.558072970882821 1.2728982691984987 1.248826850249994 1.3110527398877205 1.2224708780867146 0.9756592314875496 1.0 17.59069252584267 -7.871654116800525 0.773146012665101 0.9695718998672413 1.4028811242241153 0.7633319026590819 0.08332861622567331 0.3152480895580539 0.36428242577773584 0.08009544558258062 0.03539545405786751 1.3438347993587852e-08 7.871654116800525 0.4333092243568739 NQTAEKEEFEHQQK ddPTM_PC-9_AZD4547_30min_R2 1 NQTAEKEEFEHQQK 14 1 P11142;E9PKE3;E9PNE6;A8K7Q2;E9PS65;E9PM13 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 61.532 0.023288 27236000.0 66430.0 61005.0 78372.0 64202.0 64744.0 80862.0 76434.0 89297.0 79635.0 83219.0 False True 87553.35817016273 80723.67323220425 77332.7360726449 49401.22081101209 55755.41316278882 75805.6863570942 83236.47792772192 75498.20049092283 83844.34352192542 80305.52813989227 1.0902531892654357 1.0052069278665794 0.962981476666603 0.615165879053247 0.6942910961953063 0.943965977348915 1.0364974847400783 0.9401370271720887 1.0440668963146413 1.0 16.29321168417239 -6.993930404300406 24.984605302979944 0.9987646431362169 0.8662653540009108 0.17630515546595904 0.13355530550458108 315.7075851488092 1299555.0527755565 0.05338255545020108 0.0469530778825152 1.0140738780763016e-07 6.993930404300406 -0.13249928913530618 NQTAEKEEFEHQQK ddPTM_PC-9_Lapatinib_30min_R1 2 NQTAEKEEFEHQQK 14 1 P11142;E9PKE3;E9PNE6;A8K7Q2;E9PS65;E9PM13 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 ; 67.01899999999999 0.015898 95035000.0 435080.0 584130.0 584750.0 538910.0 594320.0 472720.0 670770.0 605880.0 526390.0 606790.0 False True 428875.6794160998 582777.4828738394 536674.1122002756 578543.2391510585 559363.2660780774 452502.8675641424 705499.1884971836 634031.3966736856 467102.4150675622 711672.8430031488 0.6026303850605161 0.8188839697951786 0.7541022781417291 0.8129342644433304 0.7859837165032901 0.635829892924747 0.9913251509219977 0.8909028957718432 0.6563443015423528 1.0 19.44085465910173 -14.5228787452683 0.07063903339240302 1.6854650726825922 0.5339117062996194 0.29441134319710305 0.11079584514799869 418.9426137755836 2.120532889225249 47.5825879888266 5.7882426238936935 3.000000000083147e-15 14.5228787452683 -1.1515533663829727 NQTYS(ph)FSPSK ddPTM_PC-9_AZD4547_30min_R2 1 NQTYSFSPSK 10 0 Q86YS7-3;Q86YS7;H0YFE9 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 NQT(0.002)YS(0.88)FS(0.083)PS(0.036)K 120.57 0.00069465 34146000.0 165010.0 137550.0 178780.0 223020.0 215760.0 186380.0 167500.0 179710.0 170940.0 192820.0 True False 217479.74757878267 182010.3475631459 176409.2603872232 171606.18462465217 185805.44828869557 174725.62913649486 182407.1755095041 151939.94882497418 179975.53941907355 186069.43048984002 1.1688096588797683 0.978185116620133 0.9480829812979715 0.9222696289921865 0.9985812704405581 0.9390345779880024 0.9803178041084192 0.8165766317711742 0.9672493700081529 1.0 17.505481527666603 -4.729902739394552 2.800033665171721 0.9422311152340758 1.229125478508127 0.6379262741201706 0.04985354416456678 0.3322740112229377 3.15466147525953 0.01263940630256503 0.23491104989964415 1.8625041993034994e-05 4.729902739394552 0.28689436327405116 NQTYSFS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NQTYSFSPSK 10 0 Q86YS7-3;Q86YS7;H0YFE9 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 NQT(0.003)YS(0.414)FS(0.452)PS(0.131)K;NQT(0.255)YS(0.018)FS(0.722)PS(0.005)K 166.62 0.0001326 61933000.0 222373.0 247035.0 193762.0 264610.0 256140.0 171312.0 200904.0 146780.0 138429.0 158415.0 True False 260016.35683304883 271559.0022025608 198382.02092647718 249784.75957719443 205951.20571637532 162328.09714245965 181872.9187009985 142927.18052626503 140453.2622430612 187134.38548754982 1.3894632787855437 1.451144328686872 1.0601045895954577 1.334788146638143 1.1005524461995648 0.8674413134686006 0.9718840192151572 0.763767600240278 0.7505475911181789 1.0 17.513715149073413 -6.379196969299407 0.8082161111234133 0.821246549507615 1.387772446312823 0.7440683350762999 0.12076493017265093 0.32019322529302396 0.4588046099549041 0.06854451168116282 0.10106449539607353 4.17640907425327e-07 6.379196969299407 0.5665258968052079 NQTYSFS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 1 NQTYSFSPSK 10 0 Q86YS7-3;Q86YS7;H0YFE9 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 NQTYS(0.032)FS(0.808)PS(0.16)K 124.12 0.00042319 42585000.0 407330.0 294510.0 292260.0 288890.0 322090.0 317870.0 284680.0 262370.0 306880.0 191430.0 True False 401521.3995048256 293828.0801896398 268231.5109562252 310135.9343087896 303145.2994533044 304275.4410911613 299419.3374500622 274560.6680287751 272315.9428103372 224518.42043555906 1.7883672917611215 1.308703667251988 1.1946971230060504 1.381338483083638 1.350202352507253 1.3552359779695402 1.333607001462052 1.2228870463997366 1.2128890907127012 1.0 17.776474289028343 -1.5228787452830992 0.0570911832861149 0.5228080419612446 2.906087153733159 0.5427514043434041 0.1290695402501658 337.0648395715762 1.447770891248862 12.811583804178271 67.80872464510647 0.029999999999809235 1.5228787452830992 2.3832791117719143 NQVALNPQNTVFDAK ddPTM_PC-9_AZD4547_30min_R2 1 NQVALNPQNTVFDAK 15 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 196.5 2.1098e-49 0.0 10897.0 15023.0 10676.0 19244.0 13160.0 12833.0 13963.0 16661.0 12618.0 13508.0 False True 14362.019328319486 19878.89095922309 10534.429264425524 14807.593116836186 11332.961158135131 12030.550481321148 15205.679950084801 14086.425281692158 13284.961719842451 13035.08903151521 1.1017967958328576 1.5250291663648383 0.8081593642326655 1.1359794383479511 0.8694195437204296 0.9229358121171732 1.1665190712024833 1.0806543206291197 1.019169235263612 1.0 13.670112816269242 -5.26293531782922 24.999990061451108 1.0065720933791098 1.3134129726900068 0.4356221577513686 0.14239231264036922 111.25368329303546 1859298.7219954615 0.035362972773997144 0.08050578008277214 5.458391502477322e-06 5.26293531782922 0.306840879310897 NQVALNPQNTVFDAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NQVALNPQNTVFDAK 15 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 ; 257.02 2.2846999999999996e-49 9675500.0 48254.0 55139.0 53103.0 60431.0 64891.0 48719.0 57424.0 49665.0 43083.0 46101.0 False True 56422.44914005717 60612.83551904393 54369.176914248994 57045.24698994541 52176.07437394117 46164.089875102116 51984.383006242584 48361.34637441725 43713.0073699717 54458.74636468478 1.0360585380027367 1.1130046055990361 0.9983552788777769 1.0474946780438177 0.9580843823422297 0.8476891767938023 0.954564445132972 0.8880363504984838 0.8026811171385789 1.0 15.732876151606714 -6.411126116546557 2.8684932219446218 0.894890701449013 1.051243481887563 0.6029365526433638 0.05715987780488551 0.17936899579740442 2.8489723047233872 0.018639883007154204 0.021254100179194865 3.8803766578671115e-07 6.411126116546557 0.15635278043854994 NQVALNPQNTVFDAK ddPTM_PC-9_Lapatinib_30min_R1 2 NQVALNPQNTVFDAK 15 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 ; 232.37 6.5584e-25 24990000.0 146727.0 139577.0 139586.0 131597.0 145498.0 117958.0 163944.0 126639.0 116183.0 142414.0 False True 144634.64607356378 139253.8180320856 128109.7778975422 141275.08237472296 136940.09370007404 112913.21131352824 172432.2181358474 132523.11025839884 103097.24707877163 167030.07014527306 0.8659198068214242 0.8337050802347789 0.7669863144170374 0.8458062805807965 0.8198529377433147 0.6760052918335177 1.0323423679692876 0.7934086966684378 0.6172376446295187 1.0 17.34974832650279 -7.987986846600753 24.991760150856223 0.7741868265459165 0.8317843051526704 0.0 0.12075675854358361 789.8902300168747 1643260.9282548842 0.06305025473278822 0.0302539219671541 1.0280474339436085e-08 7.987986846600753 0.057597478606753905 NQVAMNPT(ph)NTVFDAK ddPTM_PC-9_Lapatinib_30min_R1 1 NQVAMNPTNTVFDAK 15 0 P11142;E9PKE3;P11142-2;E9PNE6;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PPY6;E9PN25 P11142 HSPA8 Heat shock cognate 71 kDa protein 1 NQVAMNPT(0.716)NT(0.284)VFDAK 94.569 0.011488 1877500.0 9083.5 13024.0 12146.0 10675.0 14148.0 15156.0 12046.0 15174.0 13068.0 9520.0 True False 8953.967624290115 12993.843728192178 11147.402764915858 11460.075110756083 13315.842456038208 14507.813210361606 12669.682938469326 15879.039435410454 11596.14422785938 11165.519315397372 0.8019302435796691 1.1637473691235773 0.9983774556319533 1.0263808415030473 1.1925860392069285 1.2993406576580073 1.1347150616628907 1.4221496543840184 1.0385673877137243 1.0 13.4467627329333 -6.253172226630867 4.444815209773669 1.2071534211830397 1.0071654795342642 0.28004364555218986 0.1407387511489798 0.24333495490024593 12.672269197778991 0.040825461463991235 0.05043808519290233 5.582487680896056e-07 6.253172226630867 -0.19998794164877554 NQVAMNPTNTVFDAK ddPTM_PC-9_AZD4547_30min_R2 1 NQVAMNPTNTVFDAK 15 0 P11142;E9PKE3;P11142-2;E9PNE6;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PPY6;E9PN25 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 115.34 0.0029259 0.0 7556.3 6090.0 8114.4 22578.0 10262.0 10805.0 11420.0 9026.9 9261.5 13868.0 False True 9959.046219196154 8058.473403559118 8006.79775414523 17372.99092662272 8837.298435013892 10129.36164191343 12436.357876528573 7632.0000225260765 9751.04398227301 13382.485541090678 0.7441850909247826 0.6021656723495589 0.5983042335118168 1.2981886566048786 0.6603630101358322 0.7569118315735451 0.9293010508655483 0.5702976475552437 0.7286422206347697 1.0 13.708058473464598 NQVAMNPTNTVFDAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NQVAMNPTNTVFDAK 15 0 P11142;E9PKE3;P11142-2;E9PNE6;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PPY6;E9PN25 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 106.26 0.012838999999999998 5950100.0 44557.0 48415.0 48276.0 52860.0 53571.0 46330.0 60757.0 45028.0 43644.0 41056.0 False True 52099.620059135545 53221.32123641184 49427.082927749536 49898.42557443225 43074.14711264122 43900.37324069627 55001.657117412215 43846.06271110963 44282.210933663984 48499.127800882794 1.074238288841706 1.0973665640940267 1.0191334394852736 1.0288520193454693 0.8881427164934949 0.905178613127496 1.134075180552238 0.9040587882553949 0.9130516968360397 1.0 15.56567118192848 -5.707797662142326 1.8660076224369224 0.9603768825824771 1.0828967331884027 0.3249204134746084 0.06986542798175077 0.42575186107898394 3.0067510358782044 0.022178672990628184 0.0478753515539744 1.9597575121327918e-06 5.707797662142326 0.12251985060592563 NQVAMNPTNTVFDAK ddPTM_PC-9_Lapatinib_30min_R1 3 NQVAMNPTNTVFDAK 15 0 P11142;E9PKE3;P11142-2;E9PNE6;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PPY6;E9PN25 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 ;; 228.93 6.4588e-24 41870000.0 180703.0 164083.0 180485.0 169292.0 159506.0 135899.0 190490.0 153977.0 158196.0 182341.0 False True 178126.14208312827 163703.07589472973 165646.21999224785 181742.29842155715 150124.17068086166 130086.91656604192 200352.64012527175 161131.3335406744 140378.30060226834 213858.39889589 0.8329162801309627 0.7654741489691188 0.7745602737486468 0.8498253954946725 0.7019793071299703 0.6082852824002041 0.9368471902887804 0.7534487042480662 0.6564077040088894 1.0 17.706296341962066 -10.842717442735283 5.522432844829717 1.0000411010748647 0.7655780341637936 0.37879024049267496 0.09049694027371165 4.582300220026466e-05 5.643841319556662e-06 0.0876766993301858 0.021261001454953642 1.4364236840984385e-11 10.842717442735283 -0.2344630669110711 NQVVS(ph)STNGELNTDDPTAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NQVVSSTNGELNTDDPTAGR 20 0 Q9Y6M4-6;Q9Y6M4-4;Q9Y6M4-3;Q9Y6M4-5;H0YBN6 Q9Y6M4-6 CSNK1G3 Casein kinase I isoform gamma-3 1 NQVVS(0.425)S(0.147)T(0.425)NGELNT(0.003)DDPTAGR 286.16 1.0348999999999997e-106 6266400.0 18895.0 20915.0 19152.0 16876.0 32736.0 19652.0 18493.0 14641.0 16521.0 18156.0 True False 22093.55030673894 22991.302977580384 19608.65631436448 15930.492432730205 26321.61579734228 18621.414524631207 16741.209162274372 14256.689263421787 16762.58837033871 21447.539077183086 1.0301205293171891 1.0719786029922485 0.9142613632174287 0.7427655161462241 1.2272557565984095 0.8682308239476088 0.7805655046030184 0.6647237807618093 0.7815623186424941 1.0 14.388524499776691 -6.993445760314653 24.99798243114416 0.785291036412699 0.9891818748292153 0.29467539741787263 0.1386424126523267 199.46494456186468 760758.1170311995 0.049004912724459955 0.04311423278226194 1.0152061492650676e-07 6.993445760314653 0.20389083841651623 NQVVSS(ph)TNGELNTDDPTAGR ddPTM_PC-9_AZD4547_30min_R2 2 NQVVSSTNGELNTDDPTAGR 20 0 Q9Y6M4-6;Q9Y6M4-4;Q9Y6M4-3;Q9Y6M4-5;H0YBN6 Q9Y6M4-6 CSNK1G3 Casein kinase I isoform gamma-3 1 NQVVS(0.028)S(0.971)T(0.001)NGELNTDDPTAGR;NQVVS(0.001)S(0.773)T(0.226)NGELNTDDPTAGR 264.01 5.8511e-79 16499900.0 32898.0 50434.0 57269.0 59327.0 57513.0 39239.0 49578.0 68927.0 48517.0 52312.0 True False 43358.879679090955 66735.8042093761 56509.57564110015 45650.07674301293 49528.312696643334 36785.37912698204 53990.34595468769 58275.91593488963 51081.50957058139 50480.57280253358 0.8589221015518035 1.3220096465709417 1.11943214000662 0.9043098009522148 0.9811361073572753 0.7287036791534944 1.0695272053643963 1.154422636265427 1.0119043175361444 1.0 15.623440660208384 -4.4859325659003595 17.653125502224878 1.0297886704173722 0.09181626228949315 0.10915416752283369 0.14849687981286752 6182374.736888763 80966034.70598386 0.039388863869263144 187491521.66201466 3.2663854630115946e-05 4.4859325659003595 -0.9379724081278791 NQVVSS(ph)TNGELNTDDPTAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NQVVSSTNGELNTDDPTAGR 20 0 Q9Y6M4-6;Q9Y6M4-4;Q9Y6M4-3;Q9Y6M4-5;H0YBN6 Q9Y6M4-6 CSNK1G3 Casein kinase I isoform gamma-3 1 NQVVS(0.037)S(0.954)T(0.005)NGELNT(0.004)DDPTAGR 166.3 4.3069e-08 4574900.0 15802.0 13588.0 12652.0 12320.0 25462.0 9963.2 15313.0 9033.3 10588.0 11604.0 True False 18476.96649627355 14936.926840036433 12953.671662977202 11629.750341978912 20472.90388049637 9440.712252788808 13862.441783480646 8796.185446572503 10742.829469471963 13707.713342786543 1.3479247803206178 1.0896731253792042 0.9449914321263405 0.8484092168515383 1.4935316612285228 0.6887153252119054 1.0112876915955882 0.6416960456210116 0.7837068955870162 1.0 13.742700307036795 -6.804534845097619 24.99999643186111 0.8143250384731502 1.114261251187211 0.37457527123421397 0.20449091848684245 162.95813187667568 94532.09841364245 0.071484434904788 0.0630437653665466 1.568430051525062e-07 6.804534845097619 0.2999362127140608 NQVVSS(ph)TNGELNTDDPTAGR ddPTM_PC-9_Lapatinib_30min_R1 2 NQVVSSTNGELNTDDPTAGR 20 0 Q9Y6M4-6;Q9Y6M4-4;Q9Y6M4-3;Q9Y6M4-5;H0YBN6 Q9Y6M4-6 CSNK1G3 Casein kinase I isoform gamma-3 1 NQVVS(0.009)S(0.762)T(0.229)NGELNTDDPTAGR;NQVVS(0.189)S(0.623)T(0.189)NGELNTDDPTAGR 206.45 3.8709e-21 17373900.0 124001.0 136174.0 82113.0 53396.0 71539.0 56701.0 41885.0 42662.0 90506.0 30529.0 True False 122232.72300100153 135858.69746950542 75361.98610534634 57322.91996383436 67331.21667108552 54276.03040648677 44053.600355121016 44644.23226528803 80312.26120956856 35805.896972664515 3.413759557380124 3.79431068500322 2.1047367187276538 1.6009351757783559 1.8804504945788274 1.5158405457046085 1.2303448336667306 1.2468402145984785 2.2429897865952575 1.0 15.127909588061781 -5.3937412013401165 3.0680983481957593 1.5491170732832216 3.6266251455398946 0.8452839274568059 0.3486277187324412 0.08943697045386263 1.5778128261178492 0.09432698025032553 0.2296052800407868 4.0388599933571e-06 5.3937412013401165 2.077508072256673 NQYDNDVTVWS(ph)PQGR ddPTM_PC-9_AZD4547_30min_R2 2 NQYDNDVTVWSPQGR 15 0 P25786;P25786-2;B4DEV8 P25786 PSMA1 Proteasome subunit alpha type-1;Proteasome subunit alpha type 1 NQYDNDVTVWS(1)PQGR;NQYDNDVTVWS(1)PQGR 186.96 3.4293e-07 8009600.0 31746.0 23807.6 27526.6 46014.0 41886.0 33980.6 30405.8 45889.2 31259.1 32329.6 True False 41840.56764217955 31502.941117007256 27161.579298439057 35406.1832092133 36070.851904988485 31855.78771024559 33111.857296160444 38798.07856891106 32911.392209282545 31197.750544364364 1.341140528150602 1.0097824544179523 0.8706262094061646 1.1348953880140937 1.1562004079010244 1.021092455526416 1.0613539988748275 1.2436178215393687 1.0549283725594676 1.0 14.929154389550922 NQYDNDVTVWS(ph)PQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NQYDNDVTVWSPQGR 15 0 P25786;P25786-2;B4DEV8 P25786 PSMA1 Proteasome subunit alpha type-1;Proteasome subunit alpha type 1 NQYDNDVTVWS(1)PQGR 181.51 8.2964e-29 0.0 5811.9 9209.8 7081.8 8722.1 9212.0 7643.1 6977.7 6772.3 6595.4 6807.4 True False 6795.73987974258 10124.088078552219 7250.656969876059 8233.429014429727 7406.974728895312 7242.282381091425 6316.721741826741 6594.534300844979 6691.845247729063 8041.52773265125 0.8450806992991692 1.2589757089868743 0.901651677508492 1.0238637841164553 0.9210904911538832 0.9006102598745478 0.7855126478242153 0.8200598841522363 0.8321609363551615 1.0 12.973253895885088 -6.466549722470767 1.4067275590160955 0.8457890080091729 1.0279124145681917 0.23847622012398706 0.11491796912488304 0.49219559972267113 1.9916005625718225 0.04460430250370166 0.052032888227883704 3.415468446740914e-07 6.466549722470767 0.18212340655901882 NQYDNDVTVWS(ph)PQGR ddPTM_PC-9_Lapatinib_30min_R1 1 NQYDNDVTVWSPQGR 15 0 P25786;P25786-2;B4DEV8 P25786 PSMA1 Proteasome subunit alpha type-1;Proteasome subunit alpha type 1 NQYDNDVTVWS(1)PQGR 159.54 1.9347e-14 0.0 11244.0 12022.0 10958.0 10215.0 10225.0 8236.0 7812.0 7601.7 10906.0 7278.2 True False 11083.658498102932 11994.163797629473 10057.07553910324 10966.245176241064 9623.585603123454 7883.765479053715 8216.46713559043 7954.902733370217 9677.651434728677 8536.2271724081 1.2984259057595104 1.4050895735763176 1.1781639986821137 1.2846711966250832 1.1273816182200558 0.9235655658903554 0.9625408239074003 0.9318991367852867 1.1337153099685582 1.0 13.059382855405671 -6.444194229442502 2.6092482868613933 0.9844602160571312 1.2952038977033016 0.7777985309906414 0.07554032800999459 0.1300493997933318 1.7406034384539153 0.026103656535245313 0.029326107750824882 3.5958848049790296e-07 6.444194229442502 0.3107436816461704 NQYDNDVTVWSPQGR ddPTM_PC-9_Lapatinib_30min_R1 1 NQYDNDVTVWSPQGR 15 0 P25786;P25786-2;B4DEV8 P25786 PSMA1 Proteasome subunit alpha type-1;Proteasome subunit alpha type 0 210.14 1.3203e-12 5344700.0 23527.0 29803.0 31124.0 23443.0 28594.0 30776.0 26281.0 24217.0 27019.0 27613.0 False True 23191.500665676605 29733.99298459087 28565.104862114356 25167.076423555485 26912.15713796695 29459.78222236003 27641.701586079405 25342.210228505002 23975.835697316543 32385.8702579903 0.7160993507640807 0.9181162262346446 0.8820236922633482 0.7771005139917838 0.8309845288572146 0.9096492386241083 0.8535111567446484 0.7825082366669621 0.7403177838459098 1.0 14.983076891579701 -4.740297270191438 24.704651308868325 0.8474503531296544 0.7160987832447641 0.23679068907472245 0.073675577439959 2243.2251139907444 2621062.117813474 0.01815421513091567 0.807134702925238 1.8184557179222395e-05 4.740297270191438 -0.13135156988489038 NRAEASLER ddPTM_PC-9_Lapatinib_30min_R1 1 NRAEASLER 9 1 M0R286;A0A590UKA0;M0QYM8;M0R054;M0QX65;A0A590UK93;A0A590UKC5;M0QZS6;B3KNJ4;Q9UBE0-2;Q9UBE0-3;Q9UBE0 M0R286 SAE1 SUMO-activating enzyme subunit 1;SUMO-activating enzyme subunit 1, N-terminally processed 0 74.173 0.036056 2318400.0 20297.0 15324.0 18915.0 17248.0 18440.0 18050.0 16456.0 13432.0 15636.0 15602.0 False True 20007.561057986066 15288.518219503749 17359.881714011484 18516.4754576413 17355.395454434874 17278.043576605098 17308.011160173603 14056.099755926793 13874.909025620544 18298.78491164178 1.0933819461016319 0.8354936294036178 0.9486904074689156 1.0118964481549277 0.9484452403937097 0.9442180811477117 0.9458557627595349 0.7681438862634115 0.7582420959980385 1.0 14.15946023242219 -7.695949761730907 7.807099787213712 0.8227469307216765 0.957134562170977 0.27476883734811086 0.08679071634725553 0.2649161152137115 27.32546479836788 0.039254670386019604 0.022457596718533503 2.013957206707387e-08 7.695949761730907 0.13438763144930055 NREEEWDPEYT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 NREEEWDPEYTPK 13 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 NREEEWDPEY(0.001)T(0.999)PK;NREEEWDPEYT(1)PK;NREEEWDPEY(0.268)T(0.732)PK;NREEEWDPEY(0.001)T(0.999)PK 137.91 4.4508e-05 86876000.0 279511.0 263423.0 241673.0 330317.0 368980.0 333688.0 260309.0 274226.0 272181.0 313187.0 True False 368389.6838100308 348569.3332324719 238468.25811366676 254167.51899677713 317753.4960584125 312822.43660960667 283475.9967146473 231850.67278658596 286567.9319914755 302222.4184567032 1.2189356623218435 1.1533536625523644 0.7890488711307498 0.8409949212063152 1.0513895616381426 1.0350735667030673 0.9379714389230805 0.7671524633100678 0.9482021004756457 1.0 18.205251156106662 -5.1254580878261145 5.740310745632616 0.9199276802392191 1.2025464532943073 0.5710269094916687 0.09244056333631928 0.161326743038234 6.721475861615893 0.025450778665864083 0.07072796343007928 7.491036482789632e-06 5.1254580878261145 0.2826187730550882 NREEEWDPEYT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NREEEWDPEYTPK 13 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 NREEEWDPEYT(1)PK;NREEEWDPEYT(1)PK;NREEEWDPEYT(1)PK;NREEEWDPEY(0.001)T(0.999)PK 152.68 5.8652e-05 100109900.0 394653.0 344069.0 293646.0 408293.0 422409.0 371016.0 391511.0 348356.0 309476.0 293336.0 True False 461459.95814794616 378225.89644719625 300647.6342986564 385417.6669137661 339640.9887383779 351559.2678236602 354424.2437858212 339212.02411369205 314001.50102892896 346515.49475350184 1.3317152194773036 1.0915122185697699 0.867631141610351 1.1122667607921481 0.9801610429570713 1.01455569273676 1.0228236519060867 0.978923105170217 0.9061687162136801 1.0 18.402560339654237 -4.832571421107098 3.3730119354158 0.990535645301575 1.3575855959911873 0.7330242399783373 0.06318951769232699 0.13451108235775486 2.5153698164051925 0.015410613487451328 0.1188631228018989 1.4703765874199194e-05 4.832571421107098 0.3670499506896123 NREEEWDPEYT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 NREEEWDPEYTPK 13 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 NREEEWDPEY(0.018)T(0.982)PK;NREEEWDPEYT(1)PK;NREEEWDPEYT(1)PK;NREEEWDPEYT(1)PK 168.47 9.0197e-05 127354000.0 645551.0 510546.0 480246.0 517550.0 506602.0 448760.0 403817.0 395313.0 418491.0 398864.0 True False 636345.3243604442 509363.8621048522 440762.02768316877 555612.3534961892 476804.66637785325 429567.580910654 424724.6683682439 413680.6851410574 371356.13667440333 467807.11094712716 1.3602728762974399 1.0888330899322776 0.9421875327863173 1.1876953994377952 1.0192334729852857 0.9182579119863035 0.9079055414705901 0.8842975565367426 0.7938231976049954 1.0 18.835554266118997 -1.522878745493202 0.3766706624796315 0.8905178724920304 6.734048560348307 0.6516284361409697 0.09269393311665625 44.449080444736644 0.6093188011617947 0.07544459373131368 189.0405726613789 0.029999999985295844 1.522878745493202 5.843530687856276 NRENS(ph)SPCQGNGEQAGR ddPTM_PC-9_AZD4547_30min_R2 2 NRENSSPCQGNGEQAGR 17 1 Q5T5X7 Q5T5X7 BEND3 BEN domain-containing protein 3 1 NRENS(0.5)S(0.5)PCQGNGEQAGR;NRENS(0.807)S(0.193)PCQGNGEQAGR 156.15 1.2825e-05 12537700.0 8640.3 8003.299999999999 9251.2 13980.5 13803.900000000001 10888.6 8950.5 11852.4 11620.2 11079.2 True False 11387.735670595463 10590.210211938373 9128.523043373298 10757.511721571826 11887.466757658183 10207.734120697696 9747.07716058397 10020.883921056848 12234.420048891527 10691.320580246022 1.0651383601419813 0.9905427615280317 0.8538255844876403 1.0061911099596155 1.1118801151302338 0.9547683136130226 0.9116813107815047 0.9372915016290956 1.144331980045256 1.0 13.384152443730716 -8.249190842249703 24.955852090944163 1.0721660004648987 0.9774282124090268 0.1908576815576628 0.0767530051218999 1107.8314013399358 2257169.6616008068 0.05462702962668128 0.020346776575591044 5.633900306491836e-09 8.249190842249703 -0.09473778805587196 NRENS(ph)SPCQGNGEQAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NRENSSPCQGNGEQAGR 17 1 Q5T5X7 Q5T5X7 BEND3 BEN domain-containing protein 3 1 NRENS(0.73)S(0.27)PCQGNGEQAGR 55.782 0.024100999999999997 4871200.0 4693.3 3808.1 4061.1 3964.3 3677.7 4454.2 3859.2 4925.3 5200.3 3010.6 True False 5487.782993099647 4186.143001143858 4157.932025807514 3742.193123434011 2957.08108559035 4220.613910829037 3493.628637811565 4796.016093786719 5276.3445494989655 3556.397948103512 1.5430733773834469 1.1770738433183958 1.1691413858859008 1.0522425156131856 0.8314820581783446 1.1867664902572912 0.982350313095468 1.3485600216208218 1.4836204008926035 1.0 11.796201050233993 -4.720429356754226 2.960880997113666 1.128342821976645 1.6525616036276716 0.3249879428068849 0.17655199044838848 0.673636261036838 7.251444858849566 0.04789687532025304 0.911988817512936 1.90357785233611e-05 4.720429356754226 0.5242187816510266 NRENS(ph)SPCQGNGEQAGR ddPTM_PC-9_Lapatinib_30min_R1 2 NRENSSPCQGNGEQAGR 17 1 Q5T5X7 Q5T5X7 BEND3 BEN domain-containing protein 3 1 NRENS(0.867)S(0.133)PCQGNGEQAGR;NRENS(0.678)S(0.322)PCQGNGEQAGR 150.59 1.1784000000000001e-05 5750850.0 7384.400000000001 6161.2699999999995 5860.79 5607.4 4992.599999999999 3916.75 3426.2599999999998 4546.23 5290.2 3195.13 True False 7279.097101866887 6147.003957862298 5378.938469503636 6019.786901738048 4698.945083829258 3749.2397328901934 3603.6549779810657 4757.4644426285795 4694.361967724342 3747.4039632568924 1.9424372641001793 1.6403366218676618 1.4353772697696479 1.6063885721320028 1.2539200817158167 1.0004898776996825 0.9616403817988991 1.2695360546328283 1.2526970707594713 1.0 11.87167579058482 -5.3498700151337895 0.6179828482557052 1.0899528664802738 2.1008476962905402 0.7931640433323017 0.13847463759265363 0.9826416520331247 0.45461138999154044 0.08396084464025301 0.6427766982735483 4.468173051021529e-06 5.3498700151337895 1.0108948298102665 NRENSS(ph)PCQGNGEQAGR ddPTM_PC-9_Lapatinib_30min_R1 1 NRENSSPCQGNGEQAGR 17 1 Q5T5X7 Q5T5X7 BEND3 BEN domain-containing protein 3 1 NRENS(0.413)S(0.587)PCQGNGEQAGR 74.324 0.0045707000000000005 5485600.0 4997.9 3925.7 3841.4 3685.8 3920.8 3019.7 3865.1 2712.0 4220.4 2166.5 True False 4926.62902949739 3916.6102828442868 3525.5749202328134 3956.866027468359 3690.186252589386 2890.554470264509 4065.2159659204563 2838.009420642754 3745.054109217763 2540.976638320211 1.9388722254267894 1.5413798866854125 1.3874881284085716 1.557222513499441 1.4522708304114496 1.1375761692068909 1.5998635739555205 1.1168970929693023 1.473864046106911 1.0 11.311167396009862 -1.5228787452803376 0.29732386272114725 1.2241330985146686 6.287291245607931 0.5349551644263891 0.1788942891037211 44.346683857515984 0.6313988986157963 0.17626586292217858 119.05592012270094 0.029999999999999995 1.5228787452803376 5.0631581470932625 NREPVQLETLSIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NREPVQLETLSIR 13 1 J3QLI9;P62314 J3QLI9 SNRPD1 Small nuclear ribonucleoprotein Sm D1 0 ; 130.69 0.00010046 7079500.0 17475.9 22690.0 23782.0 25692.0 23938.4 25939.4 24730.0 26521.0 22883.1 17876.6 False True 20434.224705241544 24942.51324701405 24349.053073737257 24252.560534587843 19247.842363242256 24579.092200296076 22387.395370304737 25824.851851322255 23217.722046928007 21117.48606891227 0.9676447584034836 1.1811308015366813 1.1530280164163234 1.1484586969985418 0.911464664895772 1.163921317153359 1.0601354392870628 1.222913170964031 1.0994548295740354 1.0 14.366150478839415 NREPVQLETLSIR ddPTM_PC-9_Lapatinib_30min_R1 2 NREPVQLETLSIR 13 1 J3QLI9;P62314 J3QLI9 SNRPD1 Small nuclear ribonucleoprotein Sm D1 0 ; 122.46 0.00023531 22071000.0 41265.0 40697.0 44466.0 34311.0 41969.0 42323.0 40701.0 34997.0 37256.0 29601.0 False True 40676.553532925805 40602.76859691621 40810.17712372374 36834.3453981407 39500.46593422872 40512.943949731714 42808.2986284775 36623.08838282983 33059.83695692756 34717.49340914681 1.171644307771626 1.1695190121709318 1.1754931913653572 1.0609736412720445 1.1377683713715856 1.1669317099678058 1.2330469289352284 1.0548886105118684 0.9522529915197588 1.0 15.083375169015708 -7.976958429085416 5.5837564917709885 0.9833083296192209 1.1558890905417907 0.7599025912179641 0.041910960305086516 0.0832343207681329 7.851598340066449 0.026329355822883618 0.011735526839716475 1.0544878277346346e-08 7.976958429085416 0.1725807609225698 NRHS(ph)PDHPGMGSSQASSSSSLR ddPTM_PC-9_AZD4547_30min_R2 4 NRHSPDHPGMGSSQASSSSSLR 22 1 J3KR33;A0JLT2 J3KR33 MED19 Mediator of RNA polymerase II transcription subunit 19 1 NRHS(0.988)PDHPGMGS(0.009)S(0.002)QASSSSSLR;NRHS(1)PDHPGMGSSQASSSSSLR;NRHS(1)PDHPGMGSSQASSSSSLR;NRHS(0.971)PDHPGMGS(0.018)S(0.01)QASSSSSLR 83.395 0.00013065 24482500.0 5055.46 4253.139999999999 17915.2 28614.3 24365.0 21420.4 9259.900000000001 23642.1 12491.39 17899.3 True False 6662.991119899611 5627.884330314194 17677.63274241626 22017.715221528048 20982.340320513875 20080.979001799384 10084.013161196759 19988.756686411027 13151.659373721883 17272.6509551229 0.3857538218777838 0.3258263219083356 1.0234464175965559 1.2747154608017948 1.2147724385231509 1.1625881316060267 0.5838138677957792 1.1572489213349475 0.7614152227062302 1.0 14.076201899955745 -5.263549389863639 24.10998430678209 1.033112178975877 0.3557899920457179 0.6382737679087913 0.20055429785421258 64.97282219341996 742429.6714826473 0.05397122155915018 0.12206788707793324 5.45067904663368e-06 5.263549389863639 -0.6773221869301591 NRHS(ph)PDHPGMGSSQASSSSSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NRHSPDHPGMGSSQASSSSSLR 22 1 J3KR33;A0JLT2 J3KR33 MED19 Mediator of RNA polymerase II transcription subunit 19 1 NRHS(0.995)PDHPGMGS(0.005)S(0.001)QASSSSSLR;NRHS(0.999)PDHPGMGS(0.001)SQASSSSSLR;NRHS(1)PDHPGMGSSQASSSSSLR;NRHS(1)PDHPGMGSSQASSSSSLR 95.59100000000001 7.6622e-05 28525100.0 4143.05 12955.6 23319.5 25257.9 32419.4 28224.199999999997 24108.2 23693.5 20932.5 14242.400000000001 True False 4844.386536032537 14241.746347422446 23875.525319696248 23842.781750216644 26067.05129461017 26744.07326613555 21824.496767746896 23071.57073033838 21238.598212100667 16824.434377223635 0.2879375572108806 0.8464918361060895 1.4190982462993316 1.4171520549002359 1.5493567694554347 1.5895971695988065 1.2971905193610658 1.3713133061740197 1.2623662546928045 1.0 14.038270383054208 -4.951853480559569 2.211599764755303 1.3935485408759527 0.1901273251581924 0.8194888683718549 0.15944315477285578 0.16541842990090985 1.2425361874779621 0.042389088461187524 0.34468507457570463 1.1172401113887647e-05 4.951853480559569 -1.2034212157177604 down NRHS(ph)PDHPGMGSSQASSSSSLR ddPTM_PC-9_Lapatinib_30min_R1 5 NRHSPDHPGMGSSQASSSSSLR 22 1 J3KR33;A0JLT2 J3KR33 MED19 Mediator of RNA polymerase II transcription subunit 19 1 NRHS(1)PDHPGMGSSQASSSSSLR;NRHS(1)PDHPGMGSSQASSSSSLR;NRHS(1)PDHPGMGSSQASSSSSLR;NRHS(1)PDHPGMGSSQASSSSSLR;NRHS(0.998)PDHPGMGS(0.001)SQASSSSSLR 94.384 8.462799999999999e-05 17466100.0 14128.900000000001 4972.44 32788.5 13606.7 23430.399999999998 25863.1 11496.1 18816.7 34620.1 13014.0 True False 13927.419295077074 4960.926620685802 30092.756097270172 14607.382108620584 22052.269937938756 24756.995502830767 12091.311807150687 19690.99257574059 30720.819772185074 15263.452559935005 0.9124684759485622 0.3250199521507817 1.9715563028158232 0.9570169036960524 1.4447760001445347 1.6219787368301806 0.792174100824943 1.290074607852972 2.0127045078139183 1.0 13.897793713131422 -5.246361536368831 24.999149813936093 1.3706022979668548 0.6187441967899902 0.36111586908046855 0.4079392046146182 857.8264869188888 1422275.706227497 0.09970680351099946 0.2615627824298104 5.6707233914274e-06 5.246361536368831 -0.7518581011768647 NRHSPDHPGMGSSQAS(ph)SSSSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NRHSPDHPGMGSSQASSSSSLR 22 1 J3KR33;A0JLT2 J3KR33 MED19 Mediator of RNA polymerase II transcription subunit 19 1 NRHS(0.004)PDHPGMGS(0.146)S(0.052)QAS(0.645)S(0.046)S(0.046)S(0.046)S(0.015)LR 69.256 0.0031721999999999996 731430.0 0.0 0.0 1105.7 2940.1 2498.0 1881.3 620.7 967.73 2063.8 585.92 True False 0.0 0.0 1132.064081390601 2775.375728932808 2008.5348320430412 1782.641316160629 561.9028025211541 942.3281128946903 2093.9791706739916 692.1426578598316 0.0 0.0 1.6355935709714042 4.009831929033999 2.901908745595329 2.5755403108265553 0.8118309081809939 1.3614651577876373 3.0253577740010513 1.0 9.43492561286141 -5.346195114139265 4.08444248089916 2.2703160584661264 2.210296028095904e-11 0.4685445023588408 0.9355874172238702 0.19676843712710787 5.9923604141835405 0.2673231528404795 0.6111443393184081 4.506142130040883e-06 5.346195114139265 -2.2703160584440236 NRLDS(ph)PQIR ddPTM_PC-9_Lapatinib_30min_R1 1 NRLDSPQIR 9 1 B7ZM87;O75044;A0A075B7E9 B7ZM87 SRGAP2 SLIT-ROBO Rho GTPase-activating protein 2 1 NRLDS(1)PQIR 66.538 0.032492 0.0 6989.8 11121.0 7205.1 8144.7 8364.7 8001.5 6908.9 7328.4 8910.7 5695.6 True False 6890.124170227665 11095.250007772198 6612.724490490306 8743.688407922722 7872.70479163294 7659.294497407521 7266.609036492676 7668.90421763951 7907.083132169161 6680.07687109005 1.0314438446130245 1.6609464564382599 0.9899174243201855 1.3089203278129242 1.1785350593350699 1.1465877781370026 1.0878032059692324 1.1480263424555628 1.1836814582762263 1.0 12.705648989292897 -5.1624093715400585 0.1178910103033518 0.9095483037750471 1.607669819430223 0.12749652823563096 0.17444372074838982 65.31318277254927 1.4572344422022718 1.9325069208419392 7.975850283150654 6.880034697152979e-06 5.1624093715400585 0.6981215156551759 NRLENDGATALAEAFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NRLENDGATALAEAFR 16 1 P46060 P46060 RANGAP1 Ran GTPase-activating protein 1 0 120.92 0.00085043 0.0 1288.0 5165.7 4724.1 7980.8 4134.1 5203.5 8763.2 6984.6 4212.6 4118.1 False True 1506.0329608404213 5678.516557078025 4836.740460249016 7533.6616501027 3324.0527818851647 4930.6192997617745 7933.086255926174 6801.261650795424 4274.201305543786 4864.67893113834 0.30958527421007165 1.1672952393076528 0.9942568725943057 1.5486451946253759 0.6833036319433589 1.01355492717132 1.6307522794869884 1.3980905517240214 0.8786194044965714 1.0 12.248128874922346 -4.761251069274319 23.839628433185307 1.1628800156933283 0.3095838138273896 0.43605206595967705 0.2848020335571437 2.387892659151486 300816.9330002647 0.07172304600921056 0.4035731184580532 1.732801960824821e-05 4.761251069274319 -0.8532962018659387 NRLENDGATALAEAFR ddPTM_PC-9_Lapatinib_30min_R1 1 NRLENDGATALAEAFR 16 1 P46060 P46060 RANGAP1 Ran GTPase-activating protein 1 0 102.72 0.0018965 2105100.0 13042.0 13173.0 10081.0 10700.0 14109.0 10089.0 8972.2 11106.0 9742.5 8183.3 False True 12856.018688390124 13142.498727846709 9252.179093785337 11486.913694153634 13279.136359361262 9657.516988607696 9436.736614688238 11622.025304446317 8645.197056926849 9597.772501438161 1.339479414256145 1.369328010835576 0.9639923318039639 1.1968312118705042 1.383564400736887 1.00622482843395 0.9832215353379345 1.2109086043355202 0.9007503621940846 1.0 13.228483901536075 -1.5228787457519064 0.20137322385319525 0.9709314260069225 2.7760482054376934 0.3632381397468105 0.14050915598649064 63.03494425829094 0.7648657921976609 0.2636055572736582 35.97384864220776 0.029999999967425178 1.5228787457519064 1.805116779430771 NRNEQESAVHPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NRNEQESAVHPR 12 1 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;H0Y5J4;Q9UJU6-5;Q9UJU6 B4DDD6;H0Y5J4 DBNL Drebrin-like protein 0 92.11200000000001 0.0027206 901870.0 3989.2 2796.0 4062.1 6428.3 7067.4 7402.4 7568.6 6880.4 6674.2 5504.2 False True 4664.492769708542 3073.5684018797374 4158.955869600037 6068.143191829789 5682.5937037554 7014.205112819558 6851.647416081213 6699.7967903864 6771.797548654114 6502.067888776775 0.7173860454087118 0.4727062919759768 0.6396358728857344 0.9332635856208171 0.8739671441395022 1.0787652840301443 1.0537643613207803 1.0304101564289916 1.0414836732699944 1.0 12.666682904100117 -5.873324545229788 1.6918179855228892 1.0277471984755728 0.574799861481717 0.8460469529029265 0.07704926876536095 0.12628640996648183 0.7365549127636097 0.024670803957506423 0.046634944553383205 1.3386759303802356e-06 5.873324545229788 -0.4529473369938558 NRNNPS(ph)FIMGS(ph)ITPTDYTLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NRNNPSFIMGSITPTDYTLSK 21 1 A0A0A0MR93;Q53F39-4;Q53F39 A0A0A0MR93 MPPE1 Metallophosphoesterase 1 2 NRNNPS(0.999)FIMGS(0.986)IT(0.011)PT(0.002)DY(0.002)TLSK 57.278 0.039419 0.0 1123.6 1180.2 1274.1 2332.1 3142.8 1069.4 2126.2 3228.7 2236.4 900.62 True False 1313.8032878884287 1297.3624563299245 1304.4793760511582 2201.4399977702124 2526.99090077857 1013.318781428893 1924.7909436450425 3143.950046090426 2269.103119146872 1063.8952766960022 1.2348990701119875 1.2194456397616222 1.2261351324937788 2.0692262161431256 2.375225227642996 0.9524610209529477 1.8091921129893624 2.955131125174437 2.1328256350509642 1.0 10.055140432468315 -5.756036129677891 24.82192446934553 1.9572580856249857 1.2260882628858796 0.22645271092980446 0.5623000603187659 175.6380003834124 806848.6346612768 0.15942673658997902 0.26614010912298935 1.7537345996843659e-06 5.756036129677891 -0.7311698227391061 NRPDYVS(ph)EEEEDDEDFETAVK ddPTM_PC-9_AZD4547_30min_R2 1 NRPDYVSEEEEDDEDFETAVK 21 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 NRPDY(0.095)VS(0.905)EEEEDDEDFETAVK 69.726 0.0013958 5954100.0 11527.0 9567.6 10436.0 14805.0 11803.0 11633.0 12112.0 14983.0 10796.0 12903.0 True False 15192.346223505438 12660.1395953846 10297.61182123873 11391.935984969856 10164.357184610102 10905.586671020725 13189.944535946948 12667.721625088134 11366.654519529171 12451.269897367538 1.2201443185098269 1.0167749715281027 0.827033058163478 0.9149216167403417 0.8163309661096546 0.8758613989506723 1.0593252451089814 1.0173839077864948 0.9128911840496143 1.0 13.60400526892757 -4.8397209240795815 3.350815599919076 0.9265662152464268 1.2407986121136052 0.5780289949781118 0.07545922965042516 0.21206710027390124 3.9160978742105366 0.02091023082828689 0.15816886115496456 1.4463689031355794e-05 4.8397209240795815 0.3142323968671784 NRPDYVS(ph)EEEEDDEDFETAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NRPDYVSEEEEDDEDFETAVK 21 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 NRPDY(0.09)VS(0.91)EEEEDDEDFET(0.001)AVK;NRPDYVS(1)EEEEDDEDFETAVK 108.32 2.642e-05 5712500.0 17997.9 20858.4 18670.4 24259.9 25277.2 19807.8 22153.8 22435.4 22486.5 16412.4 True False 21044.588995271577 22929.084103636753 19115.57314388629 22900.696454656994 20324.314113898476 18769.044098360962 20055.231684377544 21846.49452227123 22815.322522221482 19387.838199513084 1.0854530958381994 1.1826529532422343 0.9859569152153522 1.1811887544652675 1.048302234872628 0.9680833884219406 1.034423305888803 1.1268143615320605 1.1767852757712036 1.0 14.242864327258513 -5.24115819098566 24.819775621654763 1.06869551765623 1.1340530070838257 0.11847513061839188 0.0746443966222075 1778.3648841312013 2176324.474065175 0.019353449099069844 0.05102618299728385 5.739073793975938e-06 5.24115819098566 0.06535748942759567 NRPDYVS(ph)EEEEDDEDFETAVK ddPTM_PC-9_Lapatinib_30min_R1 2 NRPDYVSEEEEDDEDFETAVK 21 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 NRPDY(0.03)VS(0.97)EEEEDDEDFETAVK;NRPDY(0.018)VS(0.982)EEEEDDEDFETAVK 74.742 0.00071944 8976100.0 33909.0 30966.0 29781.6 26518.0 27885.3 28386.4 29087.1 25801.4 28564.2 25889.8 True False 33425.451441850986 30894.300129545365 27333.071808300523 28468.222181454763 26245.14147860916 27172.37984393036 30593.08771372663 27000.22723664158 25346.999001639197 30364.817434009958 1.1007954029195968 1.0174373745762213 0.9001559738569762 0.9375397116522451 0.8643273267045375 0.8948639293808524 1.0075175910480199 0.8891944532622189 0.8347489345761526 1.0 14.89011307467716 -5.010668443111391 2.4344626812011025 0.9130527048282381 1.1072162235156728 0.569363190941728 0.052007798345881054 0.2511398059824891 2.548075063821723 0.013848512625659603 0.08336980930163745 9.757342660094696e-06 5.010668443111391 0.19416351868743476 NRPEDYQGGR ddPTM_PC-9_AZD4547_30min_R2 2 NRPEDYQGGR 10 1 Q15084-3;Q15084;Q15084-4;Q15084-5;Q15084-2 Q15084-3 PDIA6 Protein disulfide-isomerase A6 0 ; 140.17 0.00015881 25957200.0 18861.1 20386.8 20769.8 31450.1 24772.2 20392.5 21687.3 25073.7 20765.1 20254.5 False True 24858.537464748704 26976.43441439722 20494.378881253757 24199.765344201303 21333.00762929751 19117.353751292874 23617.427686132924 21199.13580130633 21862.700793208158 19545.396119989982 1.271835951143744 1.3801937934021797 1.048552751524601 1.2381312302722318 1.091459466890991 0.9781000924171944 1.208337121496263 1.0846101901012377 1.1185601283797038 1.0 14.254541203089628 -5.261286407651193 24.99996677067833 1.1037103922349265 1.3260148833749485 0.563578801095169 0.08074528783606766 9.228463747318267 1507873.6068159083 0.020279130164045436 0.04721644653025503 5.479155075307717e-06 5.261286407651193 0.22230449114002204 NRPEDYQGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NRPEDYQGGR 10 1 Q15084-3;Q15084;Q15084-4;Q15084-5;Q15084-2 Q15084-3 PDIA6 Protein disulfide-isomerase A6 0 ;;; 140.17 0.00015881 33582500.0 48749.8 50490.8 49241.5 56850.8 63039.6 57764.8 56784.5 50662.8 53230.7 43197.1 False True 57002.178287560826 55503.19294192756 50415.60410942871 53665.63398878042 50687.442913555045 54735.51219888136 51405.461075821644 49332.95518167375 54009.098284909385 51028.392281944536 1.1170678859057452 1.0876923700683856 0.987991231055644 1.0516818498271407 0.9933184379686967 1.0726481817505453 1.00738939200345 0.9667746322301696 1.058412696729611 1.0 15.63901256794241 -5.105984470497293 4.590767856330935 1.0182788750712544 1.1110545401182077 0.5328702751170797 0.03230411101166937 0.15456438073984535 5.135238414445994 0.007987997983999623 0.02381797204358042 7.83457657145368e-06 5.105984470497293 0.09277566504695334 NRPEDYQGGR ddPTM_PC-9_Lapatinib_30min_R1 3 NRPEDYQGGR 10 1 Q15084-3;Q15084;Q15084-4;Q15084-5;Q15084-2 Q15084-3 PDIA6 Protein disulfide-isomerase A6 0 ;; 112.3 0.0019077999999999999 43061300.0 28728.2 26645.6 30110.699999999997 25059.4 30262.6 27595.6 25050.2 23243.5 24404.199999999997 19540.8 False True 28318.530599893347 26583.903750300768 27635.114476663235 26902.351871707826 28482.61336656079 26415.400516485526 26347.176784430056 24323.47786456853 21655.54200838123 22918.401243520668 1.2356241737367857 1.1599370945569942 1.2058046363280268 1.1738319608708951 1.2427836071075506 1.1525847826734208 1.149607972409452 1.0613077939476732 0.9448975859301502 1.0 14.484218786711796 -7.835329794982808 1.7003408203219388 0.9702350710769326 1.1954872899964817 0.8914624725970244 0.031105922444658537 0.10748158088998422 0.5827410765600767 0.023499490392888574 0.008763271043345082 1.4610672463579849e-08 7.835329794982808 0.22525221891954905 NRPTS(ph)ISWDGLDSGK ddPTM_PC-9_AZD4547_30min_R2 2 NRPTSISWDGLDSGK 15 1 P30086 P30086 PEBP1 Phosphatidylethanolamine-binding protein 1;Hippocampal cholinergic neurostimulating peptide 1 NRPT(0.004)S(0.941)IS(0.055)WDGLDSGK;NRPT(0.005)S(0.995)ISWDGLDSGK 182.91 1.1935e-05 67267000.0 138716.0 116621.0 144055.0 184454.0 161032.0 153022.0 122532.0 156480.0 138752.0 146605.0 True False 182824.80252795876 154316.4576020475 142144.73657613507 141930.98008589185 138675.48641465188 143453.5101498265 133437.1106240632 132299.61155267892 146086.14745217792 141472.4035730893 1.2923001087876862 1.0907884061100477 1.0047523968354606 1.0032414555858282 0.9802299452911151 1.0140034842605448 0.9432024002838489 0.935161969481409 1.0326123241180742 1.0 17.11016113448268 -4.307195468564074 1.1481921990530846 0.9810862986226174 1.849520846000191 0.9150875046093351 0.028254515422623392 1.063642121215133 0.55974222355965 0.008656134913431687 1.446988151152423 4.929518847536263e-05 4.307195468564074 0.8684345473775736 NRPTS(ph)ISWDGLDSGK ddPTM_PC-9_Lapatinib_30min_R1 2 NRPTSISWDGLDSGK 15 1 P30086 P30086 PEBP1 Phosphatidylethanolamine-binding protein 1;Hippocampal cholinergic neurostimulating peptide 1 NRPT(0.224)S(0.762)IS(0.013)WDGLDSGK;NRPT(0.011)S(0.937)IS(0.052)WDGLDSGK 95.227 0.0013586 90239000.0 186241.0 220150.0 219540.0 214360.0 221140.0 207940.0 204940.0 204429.0 207339.0 179224.0 True False 183585.16918758347 219640.2562009753 201490.26864890763 230124.74948399747 208132.97997796795 199046.89093181532 215550.7904208785 213927.51764475612 183986.29844353677 210202.62959903118 0.8733723718765011 1.0448977570829951 0.95855255965759 1.0947757881191515 0.9901540260223616 0.9469286436211772 1.0254428825750141 1.0177204635966273 0.8752806698683886 1.0 17.6814211917186 -9.769696472503545 11.994845008114437 0.9999995518961754 0.9870543414098334 0.0 0.06724049154970693 0.0 0.0 0.062121457451940594 0.01506666651127438 1.6994309662220744e-10 9.769696472503545 -0.012945210486342007 NRPTSISWDGLDSGK ddPTM_PC-9_AZD4547_30min_R2 1 NRPTSISWDGLDSGK 15 1 P30086 P30086 PEBP1 Phosphatidylethanolamine-binding protein 1;Hippocampal cholinergic neurostimulating peptide 0 130.95 1.4094000000000001e-05 5828200.0 75608.0 59310.0 59654.0 61410.0 60134.0 64164.0 64969.0 57011.0 46786.0 57445.0 False True 99649.77125590356 78480.797629736 58862.94898276884 47252.87327504209 51785.432088396534 60151.81493676381 70751.11513837 48201.2599324501 49259.01244448793 55433.86803489717 1.7976333744773365 1.4157553930808173 1.061858951385333 0.8524188361760194 0.9341839911982357 1.0851094659116438 1.2763156829292555 0.8695272699012463 0.8886086104162533 1.0 15.758480058292264 -4.9918278105405545 2.0081395693850905 0.9921702613502986 1.8651335406573593 0.8264229965031151 0.11875381783805716 0.20419015670230514 1.2424346044642887 0.03581257091981037 0.28283953378081744 1.0189953201369322e-05 4.9918278105405545 0.8729632793070606 NRPTSISWDGLDSGK ddPTM_PC-9_Lapatinib_30min_R1 2 NRPTSISWDGLDSGK 15 1 P30086 P30086 PEBP1 Phosphatidylethanolamine-binding protein 1;Hippocampal cholinergic neurostimulating peptide 0 ; 126.63 2.9891999999999998e-05 12848400.0 252410.0 240770.0 236090.0 215980.0 240930.0 206340.0 248750.0 220720.0 197282.0 238530.0 False True 248810.5871136752 240212.51185786427 216679.59153375434 231863.88968815884 226758.97108660464 197515.3192020329 261629.057856902 230975.45697797486 175062.02368844143 279759.5926787535 0.8893728530673947 0.8586390534736698 0.7745206856322757 0.8287969233441335 0.8105494039197819 0.7060180396703635 0.935192446313465 0.8256212227303419 0.6257587881515979 1.0 18.0938280750676 -5.056871838848542 4.983963052253147 0.808168726497996 0.8834262428207281 0.058219751514663076 0.099283799312533 0.514730531962852 26.894385084067775 0.02423019224799092 0.07368443663999126 8.772596639927492e-06 5.056871838848542 0.07525751632273214 NRS(ph)AEEGELAESK ddPTM_PC-9_AZD4547_30min_R2 3 NRSAEEGELAESK 13 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 NRS(1)AEEGELAESK;NRS(1)AEEGELAESK;NRS(1)AEEGELAESK 156.17 5.194e-05 317643000.0 535847.0 488724.0 581044.0 641982.0 636572.0 603639.0 543220.0 572159.0 483100.0 514370.0 True False 706235.1996900064 646694.4754812852 573338.9769125954 493982.9684230265 548194.9658325545 565893.3579049505 591565.5276434207 483744.9734558369 508635.67973180226 496362.06286204344 1.4228226783042728 1.3028684580614787 1.1550821865931897 0.9952069374010999 1.1044255934300065 1.1400818077070332 1.1918024601486066 0.9745808748286363 1.0247271453402154 1.0 18.921033328397577 -5.182354189020592 1.994896693759909 1.0706136549709404 1.42245467540657 0.7651859598537 0.06699187198519593 0.20098051677439877 1.3851304074565662 0.01999493752063645 0.09473417838827389 6.5712170292215115e-06 5.182354189020592 0.3518410204356295 NRS(ph)AEEGELAESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NRSAEEGELAESK 13 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 NRS(1)AEEGELAESK;NRS(1)AEEGELAESK;NRS(1)AEEGELAESK;NRS(1)AEEGELAESK 130.47 4.5959e-05 238850000.0 652459.0 524392.0 504762.0 724890.0 740899.0 731493.0 837676.0 828031.0 766474.0 633656.0 True False 762907.4220473458 576450.1721740068 516797.4404005447 684276.7634250893 595725.1595379729 693132.2193601695 758325.265030948 806296.0636213651 777682.2322236523 748532.8167818651 1.0192037074971285 0.7701067464915089 0.6904138720629374 0.9141573329636647 0.7958571036326081 0.9259877507309873 1.013082189624208 1.0771686231310995 1.0389420674528447 1.0 19.513706041983845 -7.097328497290022 2.3104522491847495 1.0430659813125591 0.8297643106789427 0.5375402640082474 0.08444938431248467 0.23210965752962062 2.436577564952997 0.037689264926665744 0.027853301807521533 7.992294947519346e-08 7.097328497290022 -0.21330167063361638 NRS(ph)AEEGELAESK ddPTM_PC-9_Lapatinib_30min_R1 4 NRSAEEGELAESK 13 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 NRS(1)AEEGELAESK;NRS(1)AEEGELAESK;NRS(1)AEEGELAESK;NRS(1)AEEGELAESK 193.31 7.0485e-06 229894600.0 384667.0 281197.0 285985.0 290532.0 334207.0 332913.0 341207.0 354180.0 348860.0 275517.0 True False 379181.5780407122 280545.9056231922 262472.4172340245 311898.6924663405 314549.6013362431 318675.0870481069 358873.02892132686 370636.4957976597 309567.7131413396 323139.74634667445 1.1734290885835947 0.8681875528930253 0.8122566790420014 0.9652130262296047 0.9734166251364956 0.9861835031157766 1.1105815145881701 1.146985166597331 0.9579994929166827 1.0 18.301798688149212 -7.008819187295189 3.084294983849911 1.065592437731092 0.945858064977487 0.15490249577614168 0.10087152806192795 0.40614528977434206 7.912768704995679 0.04083024473784419 0.032895936988484475 9.798978678792021e-08 7.008819187295189 -0.11973437275360488 NRS(ph)PADAGR ddPTM_PC-9_AZD4547_30min_R2 1 NRSPADAGR 9 1 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 NRS(1)PADAGR 72.325 0.015377000000000002 1535300.0 3926.9 4589.0 2497.5 811.48 591.78 2384.1 865.79 2022.2 4296.0 5423.1 True False 5175.572515405874 6072.304507213928 2464.3815181624896 624.4058232410221 509.6215618663535 2235.021850114373 942.8436327425279 1709.715455533154 4523.077789542175 5233.238919663172 0.9889807430651361 1.1603338965469516 0.47090942263364216 0.1193153671801422 0.09738167312627767 0.42708194378754377 0.18016445402481496 0.32670311479744113 0.8642979728189621 1.0 12.353488410296325 -5.31616435841365 5.231075525770449 0.3742233055666429 1.0756733650779575 0.428904840885576 0.2890546845606142 0.1555237850159125 9.388215458228045 0.07451505180132031 0.1641495891982317 4.8287602339496056e-06 5.31616435841365 0.7014500595113147 NRS(ph)SDGGSEEPPDRR ddPTM_PC-9_AZD4547_30min_R2 2 NRSSDGGSEEPPDRR 15 2 Q9HCD6;Q9HCD6-2;Q9HCD6-3;Q9HCD6-4 Q9HCD6 TANC2 Protein TANC2 1 NRS(0.9)S(0.1)DGGSEEPPDRR;NRS(0.927)S(0.073)DGGSEEPPDRR 162.79 0.00011256 13057100.0 17696.6 15754.3 25617.4 32996.0 33347.1 28074.1 20719.2 25764.3 24129.8 22144.6 True False 23323.750687853397 20846.56938287216 25277.696537888183 25389.28198311822 28717.43077784559 26318.622088962693 22563.168661591146 21783.019439715572 25405.251966036965 21369.324294291648 1.0914594381481604 0.9755371342481273 1.1828963887566895 1.188118146997302 1.3438623693645209 1.231607594442897 1.0558672024841893 1.019359299326766 1.1888654791402753 1.0 14.3832536697331 -11.027852547398018 6.006166667630335 0.9998489031454911 1.1420578615984494 0.14435201768301564 0.10368106010919356 0.00023324072571344342 1.922374831712199e-05 0.11161829254956701 0.02704276702836385 9.378803840516371e-12 11.027852547398018 0.14220895845295822 NRS(ph)SDGGSEEPPDRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NRSSDGGSEEPPDRR 15 2 Q9HCD6;Q9HCD6-2;Q9HCD6-3;Q9HCD6-4 Q9HCD6 TANC2 Protein TANC2 1 NRS(0.856)S(0.144)DGGSEEPPDRR;NRS(0.632)S(0.366)DGGS(0.001)EEPPDRR 101.5 0.004669899999999999 8963200.0 12861.1 18109.1 18256.9 19070.7 22945.6 22767.3 22705.8 27127.0 20785.3 19582.8 True False 15038.230211696222 19906.851769127454 18692.213735678823 18002.230507043612 18449.574396367818 21573.342708458982 20554.94224824364 26414.94499343234 21089.2456905757 23133.00662264049 0.650076769397462 0.8605388868753633 0.8080321784624649 0.7782053928703181 0.7975432980817568 0.932578417512964 0.888554721119836 1.1418725384178892 0.9116517379083555 1.0 14.497665166391565 -7.02510347821335 1.3280794549645596 1.0126708710401753 0.778395351126712 0.6142108498694925 0.07912996391983305 0.28380892377407385 1.0162021909231975 0.04135633999651456 0.029484907401848476 9.438359641591808e-08 7.02510347821335 -0.2342755199134633 NRS(ph)SDGGSEEPPDRR ddPTM_PC-9_Lapatinib_30min_R1 1 NRSSDGGSEEPPDRR 15 2 Q9HCD6;Q9HCD6-2;Q9HCD6-3;Q9HCD6-4 Q9HCD6 TANC2 Protein TANC2 1 NRS(0.5)S(0.5)DGGSEEPPDRR 110.26 0.0015325999999999998 2438200.0 2666.5 2755.0 4369.9 2457.2 3956.4 3276.7 3199.4 3807.5 3613.9 2589.6 True False 2628.47522102379 2748.620966766695 4010.6236903018125 2637.9106849789064 3723.692330581676 3136.5631793607704 3365.0492772155703 3984.410349962124 3206.8645259459 3037.208909574897 0.8654245721252294 0.9049825180288324 1.3204964853284193 0.8685311954218261 1.2260244327753083 1.0327123595195102 1.1079413294907525 1.311865751941246 1.0558590539610753 1.0 11.568530430059804 -5.087627687690195 9.763504451590318 1.1184158542716245 0.8752250802892623 0.32454014371025997 0.1333317151446371 0.4225962747491079 44.447288115600216 0.03184349051786333 0.08467654294400256 8.172827118776895e-06 5.087627687690195 -0.24319077398236222 NRT(ph)LDNSDLQR ddPTM_PC-9_AZD4547_30min_R2 1 NRTLDNSDLQR 11 1 E7EUN2 E7EUN2 AGAP1 1 NRT(0.954)LDNS(0.046)DLQR 83.87700000000001 0.0088988 11135000.0 22416.0 23631.0 24220.0 52978.0 34106.0 36740.0 30873.0 36034.0 27884.0 34251.0 True False 29543.82171823524 31269.258620608463 23898.826974933127 40764.74060194075 29370.970612413133 34442.64199203141 33620.63719107413 30465.773278944547 29357.891313685745 33051.88291519303 0.8938619864423749 0.9460658777244686 0.723070060373096 1.233356075553636 0.8886322963135064 1.042078058923508 1.0172079235951685 0.9217560572000053 0.888236576082954 1.0 15.01244484175241 -5.726418346121561 24.999999126787873 0.9934788284458277 0.8635062412119588 0.2734580132674719 0.10732271424932283 263.2252525659583 187903.2406231485 0.028270922712801377 0.04896410074598838 1.8775073847495942e-06 5.726418346121561 -0.12997258723386884 NRT(ph)LDNSDLQR ddPTM_PC-9_Lapatinib_30min_R1 1 NRTLDNSDLQR 11 1 E7EUN2 E7EUN2 AGAP1 1 NRT(0.971)LDNS(0.029)DLQR 110.51 0.019858 7198100.0 32837.0 24229.0 30930.0 22680.0 26936.0 22082.0 22372.0 23930.0 25694.0 18959.0 True False 32368.7383584317 24172.89923912533 28387.054793252708 24347.9628582621 25351.67743821354 21137.604335656175 23530.31269296328 25041.875160759995 22800.071150185107 22236.037888720457 1.4556882174972006 1.0871046073989366 1.2766237823174622 1.0949775755964577 1.1401166684948643 0.9506012015916974 1.0582061791187793 1.126184227877343 1.0253657267669418 1.0 14.440612125006316 -1.5228787452803492 0.5167670927672195 1.0466180527534743 13.518686688577304 0.644934056953397 0.08325551358903852 75.63064938792941 0.7663996147068461 0.042986685646819386 1032.2977389765972 0.029999999999999197 1.5228787452803492 12.47206863582383 NRT(ph)PAAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NRTPAAVR 8 1 Q92688;Q92688-2 Q92688 ANP32B Acidic leucine-rich nuclear phosphoprotein 32 family member B 1 NRT(1)PAAVR 63.076 0.042847 7407000.0 5479.9 7627.5 10153.0 4680.3 5030.0 5835.8 2963.7 7774.8 8949.5 5642.8 True False 6407.538837041476 8384.707791608616 10395.086025466926 4418.077964737332 4044.4076081571266 5529.760374661244 2682.956880670123 7570.719738081536 9080.369506709414 6665.794971619779 0.9612565139375195 1.2578706406823588 1.5594668107442455 0.6627983584175174 0.6067404751236057 0.8295725263385231 0.40249616018690243 1.1357564657050743 1.3622335438413427 1.0 12.702561227976377 -5.772420900891659 24.997866727151173 0.8322232532501069 1.2593652986433033 0.2845380244529395 0.2905760620768257 266.5656432921419 606798.7639679099 0.08675880199285141 0.13008017439210653 1.6888034173441402e-06 5.772420900891659 0.42714204539319633 NRVPS(ph)AGDVEK ddPTM_PC-9_AZD4547_30min_R2 3 NRVPSAGDVEK 11 1 Q15785 Q15785 TOMM34 Mitochondrial import receptor subunit TOM34 1 NRVPS(1)AGDVEK;NRVPS(1)AGDVEK;NRVPS(1)AGDVEK 68.57600000000001 0.017394 106592900.0 170229.0 126859.0 161678.0 228997.0 215922.0 179785.0 179404.0 166757.0 167040.0 198760.0 True False 224358.28101683955 167863.6908870455 159534.04408147134 176205.27961838158 185944.95738501963 168543.0155290517 195370.60844840025 140988.53734464524 175869.3933810812 191801.47289783595 1.1697422216165418 0.8751950042451393 0.8317665222855091 0.9186857481133017 0.9694657427582122 0.8787368156386736 1.0186084887495386 0.7350753631581521 0.9169345298758939 1.0 17.54925427369924 -4.758297830645904 24.995602728707674 0.8995544680181623 1.1697425928275587 0.5014059611418347 0.0790532574430095 71.05321869755393 565235.5027941737 0.01904024646649098 0.13210581324506665 1.7446253127282337e-05 4.758297830645904 0.27018812480939636 NRVPS(ph)AGDVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 NRVPSAGDVEK 11 1 Q15785 Q15785 TOMM34 Mitochondrial import receptor subunit TOM34 1 NRVPS(1)AGDVEK;NRVPS(1)AGDVEK;NRVPS(1)AGDVEK;NRVPS(1)AGDVEK;NRVPS(1)AGDVEK;NRVPS(1)AGDVEK 63.062 0.024735 189683000.0 277526.0 263228.0 232026.0 321962.0 342052.0 290559.0 312528.0 324478.0 279071.0 237216.0 True False 324505.6704116448 289359.5362267521 237558.37980350503 303923.51295488793 275029.3660408275 275321.57454011356 282923.0853332225 315960.79631285934 283151.88542453817 280221.38299917756 1.1580332198010643 1.0326104779363015 0.8477525064680815 1.0845835878119978 0.98147173173303 0.9825145090405953 1.0096413139680096 1.1275399219401707 1.0104578115845257 1.0 18.09620752288874 -7.583984570155803 24.99838119295613 1.055117583689845 1.00830994414206 0.02527590578278005 0.08140458679735205 222.08818513059796 90852.82441595274 0.03828534328339694 0.022104056339373734 2.606246144446353e-08 7.583984570155803 -0.046807639547784996 NRVPS(ph)AGDVEK ddPTM_PC-9_Lapatinib_30min_R1 2 NRVPSAGDVEK 11 1 Q15785 Q15785 TOMM34 Mitochondrial import receptor subunit TOM34 1 NRVPS(1)AGDVEK;NRVPS(1)AGDVEK 70.529 0.015097 95327200.0 260961.0 192386.0 211479.0 183127.0 220221.0 223755.0 147964.0 160823.0 175569.0 183107.0 True False 257239.64828561308 191940.5420371606 194092.01295254758 196594.77047376352 207268.03375114457 214185.52024838087 155624.85192658755 168295.4236932259 155794.57039646793 214756.8009752594 1.1978184025717902 0.8937576885365912 0.9037758621432788 0.9154297772223372 0.9651290800100084 0.9973398713135779 0.7246562214554313 0.7836558513116146 0.7254465036216288 1.0 17.712344294172695 -7.254094936545905 24.64529471050746 0.7904109634333654 0.9680838445773513 0.3634654285757464 0.10890006056489689 487.4475663113401 1635701.4372667817 0.04088205682084646 0.031005438233018403 5.570639617313174e-08 7.254094936545905 0.17767288114398594 NS(ph)CNVGGGGGGFK ddPTM_PC-9_AZD4547_30min_R2 2 NSCNVGGGGGGFK 13 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 NS(1)CNVGGGGGGFK;NS(1)CNVGGGGGGFK 102.5 0.0017331 14832100.0 27203.0 31957.0 28705.0 45253.0 33138.0 39394.0 33632.0 35036.0 34243.0 30820.0 True False 35852.98814244976 42286.47529680439 28324.352944486178 34820.62000188047 28537.360703516864 36930.68695247917 36625.1828461829 29621.991247186026 36053.01507152997 29741.001180877905 1.2055071019432115 1.4218242028783028 0.9523671638430731 1.1707951521238136 0.9595292549150993 1.2417432327807412 1.2314710800566864 0.9959984557020092 1.2122327305750016 1.0 14.860165593663913 -5.254260817745978 24.938810699696127 1.1032838701439316 1.3136656465431469 0.34913471483739966 0.11876283948607474 582.1018128954126 2022248.3372869133 0.028997673319278702 0.07331962459541995 5.568512286734306e-06 5.254260817745978 0.2103817763992153 NS(ph)CNVGGGGGGFK ddPTM_PC-9_Lapatinib_30min_R1 1 NSCNVGGGGGGFK 13 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 NS(1)CNVGGGGGGFK 105.46 0.0012265000000000002 4392000.0 1674.6 8454.9 9449.9 7476.9 14257.0 18973.0 21760.0 19602.0 20377.0 20368.0 True False 1650.719896915971 8435.323198517504 8672.965699668886 8026.776168207227 13418.431290340463 18161.56901822318 22886.6263275023 20512.780480619193 18081.927680677283 23888.581661345954 0.06910079134530604 0.35311109374763244 0.3630590473147507 0.3360089050910599 0.5617089989085785 0.7602615038301066 0.9580571442855934 0.8586855750339863 0.7569276375221389 1.0 14.54403357863935 -6.508851560171537 1.1958279040263087 0.894606117249334 0.2488310056097127 0.8974867789882797 0.09473725205767448 0.14115281521150763 0.42312624315226466 0.04355712861659857 0.05001588876347203 3.098478163634541e-07 6.508851560171537 -0.6457751116396213 down NS(ph)DEADLVPAK ddPTM_PC-9_AZD4547_30min_R2 2 NSDEADLVPAK 11 0 B5MD17;J3KS05;P83916 B5MD17 CBX1 Chromobox protein homolog 1 1 NS(1)DEADLVPAK;NS(1)DEADLVPAK 95.822 0.0060596 2436500.0 37658.0 42013.0 45649.0 46020.0 40993.0 51211.0 46687.0 56138.0 44268.0 47281.0 True False 49632.460664940336 55592.88064100646 45043.66443347327 35410.800001912336 35301.82954068644 48008.76807441265 50842.05255529682 47463.16202290584 46607.91610508685 45625.706581216335 1.087817907577864 1.21845522637656 0.9872431093925746 0.7761151038588107 0.7737267471758973 1.0522306759009712 1.1143291000829783 1.0402723722956209 1.021527546584339 1.0 15.477559280858474 -5.335724067802406 6.734745178777888 0.9653756741310809 1.1523649674000636 0.30541211531538104 0.11002764269090953 0.30270547498520867 22.94543106325415 0.03309583205447521 0.06989683640440178 4.616107692107412e-06 5.335724067802406 0.18698929326898261 NS(ph)DEADLVPAK ddPTM_PC-9_Lapatinib_30min_R1 2 NSDEADLVPAK 11 0 B5MD17;J3KS05;P83916 B5MD17 CBX1 Chromobox protein homolog 1 1 NS(1)DEADLVPAK;NS(1)DEADLVPAK 94.728 0.006513 3703500.0 20408.1 29726.0 25968.0 25166.0 32944.0 35954.0 37650.0 36920.0 36383.0 35644.0 True False 20117.076751612807 29657.171273360007 23833.011279378807 27016.791591314992 31006.298690396015 34416.33123286758 39599.332777135176 38635.43798308648 32285.163410025078 41805.01790735546 0.48121201134740504 0.7094165427481356 0.570099296026984 0.6462571467183004 0.7416884441745581 0.8232583779568753 0.9472387469105186 0.9241818307244092 0.7722796215892687 1.0 15.351388500696956 -6.5659848421433855 1.3812840195242981 0.9062554840890539 0.5955741877410039 0.772987424200336 0.07583901040833327 0.19593775443095324 0.7744145905090863 0.03151375643765086 0.033796956599938775 2.7165340803488304e-07 6.5659848421433855 -0.31068129634805 NS(ph)FTPLSSSNTIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NSFTPLSSSNTIR 13 0 O60825 O60825 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2;6-phosphofructo-2-kinase;Fructose-2,6-bisphosphatase 1 NS(0.925)FT(0.059)PLS(0.002)S(0.007)S(0.007)NT(0.001)IR;NS(0.774)FT(0.223)PLS(0.003)SSNTIR;NS(0.771)FT(0.229)PLSSSNTIR;NS(0.992)FT(0.008)PLSSSNTIR 173.19 0.00014379 39201000.0 107957.0 113562.0 97043.0 130699.0 134195.0 125944.6 148458.0 136139.0 127979.0 107011.4 True False 126231.98785205721 124835.6848548883 99356.8731576269 123376.35876187489 107900.45307686784 119339.84346320314 134394.98349715705 132565.49550119397 129850.45076251916 126411.71971822366 0.9985782025071166 0.9875325257274532 0.7859783363369869 0.9759882947315748 0.8535636831567666 0.9440567989203534 1.0631528769383756 1.0486804213777592 1.027202628458505 1.0 16.94777069741039 -7.156242315361337 4.8987100927337295 1.0383882309259063 0.9180836535787144 0.43215377062112637 0.06226363467600098 0.21303772096381787 7.966256659021999 0.024430460141855043 0.018732777898065774 6.978429327564219e-08 7.156242315361337 -0.12030457734719191 NS(ph)GIWESPELDR ddPTM_PC-9_AZD4547_30min_R2 2 NSGIWESPELDR 12 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 NS(1)GIWESPELDR;NS(0.999)GIWES(0.001)PELDR 145.69 3.5406e-07 3370600.0 22644.3 29327.0 31208.0 34358.0 33746.0 35196.5 34021.0 43938.0 34609.0 33196.1 True False 29844.716369300255 38806.379229257545 30794.16152905506 26437.29392580845 29060.95039836082 32995.65729103249 37048.803092590046 37148.391694795646 36438.36108432616 32033.91464310644 0.9316599829213414 1.211415453328259 0.9612987320512147 0.825290765126567 0.9071932269949595 1.0300226387764635 1.1565493479443603 1.1596581969038187 1.137493231479517 1.0 14.967312490216 -7.069177169468311 4.528839833495794 1.1252251989882627 0.9720967962035812 0.31114263998496794 0.10149061676033143 0.2884872881604216 11.353912363784685 0.04254030404759197 0.03323663316954767 8.527521647002023e-08 7.069177169468311 -0.15312840278468143 NS(ph)GIWESPELDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSGIWESPELDR 12 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 NS(1)GIWESPELDR 121.95 0.00042302 2487400.0 12693.0 12352.0 12648.0 15522.0 17546.0 11854.0 16706.0 10880.0 11253.0 11180.0 True False 14841.674201822558 13578.224928475864 12949.576287807105 14652.35266300297 14107.98725501489 11232.355372225642 15123.486739033991 10594.411528312898 11417.553836415556 13206.845499168694 1.1237864638271697 1.0281202221477146 0.980520010521984 1.109451357171193 1.0682329293473538 0.8504949477097058 1.1451248324201218 0.8021909190184563 0.8645178621294718 1.0 13.68899829456935 -7.182289794315266 0.9777826705479671 0.9009503868916177 1.0568342806573179 0.24608508311520083 0.10049205238351688 0.7693287726094796 1.4569090467404207 0.07092639822121076 0.04334687412958345 6.572191443989984e-08 7.182289794315266 0.15588389376570022 NS(ph)GIWESPELDR ddPTM_PC-9_Lapatinib_30min_R1 2 NSGIWESPELDR 12 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 NS(0.957)GIWES(0.043)PELDR;NS(0.962)GIWES(0.038)PELDR 125.36 0.00029539999999999997 6088000.0 12768.3 17664.699999999997 17115.6 18449.2 20716.0 18643.7 18144.0 18877.0 20185.2 15687.6 True False 12586.221700580552 17623.79847246593 15708.421436126599 19806.01571272702 19497.52560922305 17846.352411587402 19083.407540726163 19754.094333876572 17911.73021642082 18399.180757586953 0.6840642453817184 0.9578577820753627 0.8537565690064318 1.0764618258647172 1.05969531285697 0.9699536434103682 1.0371878939695218 1.0736398861525895 0.9735069431846778 1.0 14.167353909783953 -4.133891928357104 0.9001193230189024 1.0253518931200563 9.349481181238248e-17 0.724830667968902 0.060027177525061114 3.1178195047886157 0.8658503972460887 0.01979334422839995 4.150947601195316 7.346966703828588e-05 4.133891928357104 -1.0253518931200563 NS(ph)IAGFPPR ddPTM_PC-9_Lapatinib_30min_R1 1 NSIAGFPPR 9 0 Q96S53-3;Q96S53-2;Q96S53;A0A5F9ZGZ0 Q96S53-3 TESK2 Dual specificity testis-specific protein kinase 2 1 NS(1)IAGFPPR 62.107 0.035732 2709400.0 4400.8 5184.5 5988.7 4046.4 5437.2 3282.1 5348.8 4018.6 5582.2 3993.5 True False 4338.043784992119 5172.4956087847295 5496.332203050517 4343.9857543947 5117.394585946488 3141.7322339487846 5625.7346921206 4205.318826620564 4953.473852828023 4683.771153995736 0.9261861099450437 1.104344221508786 1.1734843617117336 0.927454739262578 1.0925799783323802 0.6707697986628927 1.2011122036398538 0.8978489102809809 1.057582381795533 1.0 12.19345487308428 -5.783480964595964 24.997882603242935 0.9751814592192195 1.07163893435093 0.07563605901908899 0.14344207897624767 575.1609842393881 652301.6743171205 0.038678232854493226 0.057418410500694676 1.6463381247965799e-06 5.783480964595964 0.09645747513171055 NS(ph)IQFTDGYEVK ddPTM_PC-9_AZD4547_30min_R2 1 NSIQFTDGYEVK 12 0 B4DG22;B1AXG1;B7ZB17;P51812;A0A2R8Y603 B4DG22 RPS6KA3 Ribosomal protein S6 kinase alpha-3 1 NS(1)IQFTDGYEVK 149.0 0.00015615 8640500.0 43389.0 51843.0 40144.0 21573.0 20068.0 34118.0 44460.0 41862.0 45723.0 30903.0 True False 57185.799452735075 68600.23590487932 39611.664330376356 16599.678149527488 17281.904598894824 31984.59606652498 48416.85386956743 35393.18979306144 48139.824434645445 29821.095376141147 1.917629072018847 2.30039289434566 1.3283101720692765 0.5566421333673857 0.5795194435654933 1.0725493367394807 1.623577311928794 1.186850762744897 1.6142875983408878 1.0 14.86404563062161 -5.374978542783244 4.727368389070885 1.089212994864284 2.1014919962540204 0.569711468514688 0.3476924099297654 0.1649718303079728 5.664836933440899 0.1021192300711281 0.2223654999614831 4.217173387308678e-06 5.374978542783244 1.0122790013897365 NS(ph)IQFTDGYEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSIQFTDGYEVK 12 0 B4DG22;B1AXG1;B7ZB17;P51812;A0A2R8Y603 B4DG22 RPS6KA3 Ribosomal protein S6 kinase alpha-3 1 NS(0.984)IQFT(0.016)DGYEVK;NS(0.968)IQFT(0.01)DGY(0.022)EVK 118.13 0.00059906 7287400.0 40331.8 66392.0 41721.7 42528.0 42731.0 27033.1 43223.0 26034.2 31967.3 37075.3 True False 47159.17715063948 72982.95899055776 42716.503558428376 40145.29403763628 34358.1672970501 25615.43664694727 39128.60453257912 25350.82983551504 32434.76128631007 43796.75840208668 1.0767732332535507 1.6664009313319526 0.9753348219578087 0.9166270633336091 0.7844911027801802 0.5848706064448558 0.8934132561444286 0.5788289079017138 0.7405744733099865 1.0 15.418536472885043 -5.568776616575862 2.496927019002378 0.7570661298216824 1.371142906185941 0.5914169190268186 0.18865841870555203 0.16919615967259305 2.110830554268601 0.05063310049092665 0.11098353064472402 2.6991273968511012e-06 5.568776616575862 0.6140767763642586 NS(ph)KRDYTGCS(ph)TS(ph)ES(ph)LSPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSKRDYTGCSTSESLSPVK 19 2 O95297-4;O95297-2;O95297 O95297-4 MPZL1 Myelin protein zero-like protein 1 4 NS(0.848)KRDY(0.087)T(0.099)GCS(0.948)T(0.327)S(0.613)ES(0.612)LS(0.465)PVK 54.004 0.039327999999999995 0.0 1299.4 535.08 361.4 1203.8 1245.1 790.6 1082.1 941.88 681.13 447.34 True False 1519.362755680157 588.1992061794746 370.0171466171325 1136.354988772258 1001.1315930251365 749.1395442282425 979.5956542744341 917.1566480043512 691.0902376786395 528.4392008585087 2.875189337225138 1.1130877596209348 0.7002076038567884 2.1503987344733737 1.8945066743698915 1.4176456686240941 1.8537528114548867 1.7355954034339758 1.3077951759746174 1.0 9.045593682828864 -8.48457867364 3.196649745125859 1.00353606890232 1.6774830061064339 0.14900338504554977 0.5553136535587134 0.46027970806327784 10.638130742737296 0.5330010854119616 0.14176300938633035 3.2765841520537947e-09 8.48457867364 0.6739469372041138 NS(ph)LESISSIDR ddPTM_PC-9_AZD4547_30min_R2 2 NSLESISSIDR 11 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 NS(0.602)LES(0.398)ISSIDR;NS(0.999)LES(0.001)ISSIDR 158.31 0.00045958 19182300.0 12539.9 23364.9 21567.0 16319.6 15976.4 20192.9 18452.8 27224.0 21413.0 12441.0 True False 16527.32735387662 30917.146999477587 21281.007488372525 12557.368355306586 13758.352632737857 18930.23477084625 20095.0634521897 23017.15634528464 22544.847464494087 12005.444376745685 1.3766526948298337 2.5752605259130186 1.7726130595876506 1.0459728071065797 1.1460094437976425 1.576804171240321 1.6738292079478085 1.9172265201501768 1.8778852957882195 1.0 13.551401184888883 -11.39955211685735 2.4529354204331257 0.6688960099183942 1.6645434412880242 0.189188997714546 0.41141472979643184 17338689.93253584 9569690.101640383 33324667.479152277 0.11077897872820973 3.985179458959363e-12 11.39955211685735 0.9956474313696301 NS(ph)LESISSIDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NSLESISSIDR 11 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 NS(0.604)LES(0.396)ISSIDR;NS(1)LESISSIDR;NS(0.525)LES(0.444)IS(0.03)SIDR 153.0 0.00040395 19201400.0 28610.199999999997 47224.0 33369.3 23516.899999999998 47499.0 25088.399999999998 36961.0 16369.9 22498.1 21415.8 True False 33453.34178279239 51912.086627456665 34164.950665774966 22199.324335818495 38191.91192442449 23772.720138395962 33459.78650553307 15940.207470342748 22827.092150276458 25298.315012620475 1.3223545428264154 2.051997795171713 1.3504832495259556 0.8775020915323413 1.509662280091454 0.939695791065 1.3226092919169168 0.6300896902576602 0.9023167012857889 1.0 14.626753677358755 -5.7830960850728435 0.5398891661106071 0.8936055091083674 1.8271571980941235 0.4029593046555948 0.2991341294041606 1.5768339035782197 0.7263976603249013 0.20883049416951183 0.8269914363452847 1.6477977857273402e-06 5.7830960850728435 0.933551688985756 NS(ph)LESISSIDR ddPTM_PC-9_Lapatinib_30min_R1 2 NSLESISSIDR 11 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 NS(0.999)LES(0.001)ISSIDR;NS(0.998)LES(0.002)ISSIDR 182.72 0.00011320000000000001 15936400.0 22088.0 57461.0 26184.0 15159.3 31920.0 21442.3 32462.0 31282.0 33339.0 26367.0 True False 21773.021069556875 57327.952584893304 24031.2525931629 16274.165491942347 30042.528357134564 20525.262813442627 34142.723522214124 32735.475920555527 29584.010744766154 30924.500818180943 0.7040702515319572 1.8538036530306548 0.7770942766207755 0.5262547514550191 0.9714798157541203 0.6637217180681391 1.1040670865781976 1.0585611749409352 0.9566528145014811 1.0 14.916462687024424 NS(ph)LGGDVLFVGK ddPTM_PC-9_AZD4547_30min_R2 3 NSLGGDVLFVGK 12 0 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 NS(1)LGGDVLFVGK;NS(1)LGGDVLFVGK;NS(1)LGGDVLFVGK 124.25 0.0003279 8494700.0 76613.0 63887.0 80984.0 102066.0 91613.0 86580.0 80197.0 87758.0 77450.0 87004.0 True False 100974.3403506046 84537.2233716227 79910.09924599434 78536.26060398067 78894.116305489 81166.13891317576 87334.3776378252 74197.01757822113 81543.84888269127 83958.01644195656 1.2026765832469624 1.006898768625228 0.9517864122151969 0.9354230117891821 0.9396853290362283 0.9667467426328381 1.0402148757075846 0.8837395250936689 0.9712455384062784 1.0 16.35738046205426 -4.751335263196318 2.7771192575803467 0.9586311974394437 1.2594478392152595 0.7742448974697901 0.038976407855099184 0.22050130835161222 2.167561459954232 0.009936052388216925 0.15906516853910652 1.7728203847406417e-05 4.751335263196318 0.3008166417758158 NS(ph)LGGDVLFVGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NSLGGDVLFVGK 12 0 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 NS(1)LGGDVLFVGK;NS(1)LGGDVLFVGK;NS(1)LGGDVLFVGK 101.39 0.0027369 8828600.0 57993.0 51695.0 47623.0 61842.0 67561.0 52983.0 60412.0 54194.0 53660.0 42710.0 True False 67810.06948603925 56826.93795964699 48758.512931233265 58377.19323446917 54322.90704069649 50204.47820875917 54689.338014995934 52771.46492328941 54444.675985253605 50452.98490782602 1.3440249295442752 1.1263345085224534 0.966414831953185 1.1570612391143973 1.0767035318116567 0.9950744896556495 1.0839663523359306 1.0459532774859421 1.0791170450017995 1.0 15.622652004368302 -4.805504777551374 3.4180374676881935 1.055502603394937 1.3728976814604221 0.7398716709708366 0.05224679031992668 0.13583643274847274 2.603382881337445 0.01273202471782744 0.10929184649318001 1.564931103763516e-05 4.805504777551374 0.31739507806548506 NS(ph)LGGDVLFVGK ddPTM_PC-9_Lapatinib_30min_R1 3 NSLGGDVLFVGK 12 0 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 NS(1)LGGDVLFVGK;NS(1)LGGDVLFVGK;NS(1)LGGDVLFVGK 125.52 0.00029049 10181900.0 64664.0 55920.0 54511.0 53532.0 59613.0 51921.0 48647.0 49788.0 51709.0 49010.0 True False 63741.87950207473 55790.520675714586 50029.31599854508 57468.92185751705 56106.68054366737 49700.45986376251 51165.70362840093 52101.33224003004 45884.98790009033 57481.3131982799 1.1089148099696193 0.9705853532480551 0.8703579165975314 0.9997844283633517 0.9760855732388927 0.8646368201840205 0.890127604633988 0.9064046964325294 0.7982592141173179 1.0 15.810805401035111 -6.7518345654094745 23.89253205209035 0.885926083447281 0.9787729251704577 0.29605743278881325 0.07127065749844867 154.5465248785206 384442.09397442365 0.023564052541989428 0.02324883656489309 1.7707833694481916e-07 6.7518345654094745 0.0928468417231767 NS(ph)LSDPNIDR ddPTM_PC-9_AZD4547_30min_R2 3 NSLSDPNIDR 10 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 NS(0.99)LS(0.01)DPNIDR;NS(0.947)LS(0.053)DPNIDR;NS(0.956)LS(0.044)DPNIDR 156.08 0.00031038 24113000.0 154371.0 170435.0 167766.0 171102.0 143550.0 191097.0 170677.0 184461.0 174318.0 151246.0 True False 203457.76688373036 225524.78071192073 165541.3132236428 131657.0773995483 123620.56035336619 179147.67438081763 185866.92235483954 155956.79094209315 183532.09360274958 145950.9235756997 1.3940149325482263 1.545209685466285 1.1342258696827103 0.9020640238104578 0.8470008775877905 1.2274514610241565 1.2734891825363255 1.0685563826610782 1.2574918274330604 1.0 17.15512381466285 -5.321306428404272 5.842292783752995 1.0854375119979163 1.4689679953199213 0.542963717977456 0.14001864814746004 0.1571644711204689 11.258112945811758 0.040022972575431165 0.08621397681729706 4.77192458596722e-06 5.321306428404272 0.383530483322005 NS(ph)LSDPNIDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSLSDPNIDR 10 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 NS(0.997)LS(0.003)DPNIDR 93.348 0.006851 5065400.0 34712.0 55061.0 42864.0 50631.0 88504.0 90326.0 126740.0 91245.0 92975.0 98739.0 True False 40588.05600674897 60527.092194527984 43886.04032262524 47794.30921791675 71162.27653128009 85589.14555016476 114734.26968186088 88849.91543206875 94334.58348358114 116639.59908250594 0.3479783566303129 0.5189240418403159 0.37625335364520673 0.4097605752580568 0.6101039191753642 0.7337914929699184 0.9836648152460014 0.76174743509895 0.8087697850954788 1.0 16.831698140343633 -6.659880530210917 1.8261151876305537 0.868647245590414 0.4163406292034242 0.8669314010835767 0.08325832035722197 0.1196187662841283 0.8203594434174838 0.03258060152662862 0.03209833297304476 2.1883635366705605e-07 6.659880530210917 -0.45230661638698977 NS(ph)LTGEEGQLAR ddPTM_PC-9_AZD4547_30min_R2 2 NSLTGEEGQLAR 12 0 Q9BX95 Q9BX95 SGPP1 Sphingosine-1-phosphate phosphatase 1 1 NS(0.996)LT(0.004)GEEGQLAR;NS(0.999)LT(0.001)GEEGQLAR 145.86 0.00011546 20938000.0 37977.0 37537.0 41485.0 39001.0 45135.0 34335.0 37481.0 38226.0 38858.0 31975.0 True False 50052.89602932815 49670.101173957075 40934.88179418251 30009.92200944337 38868.78433681075 32188.027022220955 40816.736389681915 32319.050046093518 40911.95454982073 30855.56498243256 1.6221675428022622 1.6097615195909218 1.3266612300727132 0.9725935022265626 1.2597009440255096 1.0431838483770115 1.3228322480214085 1.0474301820269434 1.3259181795281894 1.0 14.913243090918128 -5.40194339379505 3.3076857762097513 1.1489912028292804 1.6194198165837388 0.7001099212309172 0.12344557317516179 0.12321896374618369 2.482078529935216 0.03082606950798391 0.0723638616487533 3.963296887399181e-06 5.40194339379505 0.47042861375445844 NS(ph)LTGEEGQLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NSLTGEEGQLAR 12 0 Q9BX95 Q9BX95 SGPP1 Sphingosine-1-phosphate phosphatase 1 1 NS(0.999)LT(0.001)GEEGQLAR;NS(0.982)LT(0.018)GEEGQLAR;NS(0.994)LT(0.006)GEEGQLAR 139.0 7.1119e-05 15938500.0 51938.6 56015.4 54778.6 45215.8 63810.0 39263.9 46783.3 37094.5 34798.5 32108.5 True False 60730.77914588994 61576.23871911811 56084.729572997356 42682.50531760149 51306.888563917695 37204.83196385443 42351.64714223926 36120.80867987155 35307.36223020588 37929.51687925383 1.6011482386981741 1.623438519270944 1.4786565763950927 1.1253110724684021 1.3526902735737412 0.9808939059860321 1.1165880988429933 0.9523139668469761 0.9308677023913747 1.0 15.211033375216834 -5.738160626020911 0.577431500134823 0.9568438337455543 1.7899243420379978 0.8564114871785728 0.09829484749629933 0.5169222431007112 0.27122521504291647 0.06143486831557305 0.254300421393862 1.8274242090087246e-06 5.738160626020911 0.8330805082924435 NS(ph)LTGEEGQLAR ddPTM_PC-9_Lapatinib_30min_R1 2 NSLTGEEGQLAR 12 0 Q9BX95 Q9BX95 SGPP1 Sphingosine-1-phosphate phosphatase 1 1 NS(0.896)LT(0.104)GEEGQLAR;NS(0.99)LT(0.01)GEEGQLAR 144.18 5.6492e-05 18658000.0 42245.0 69256.0 38040.0 19542.6 34258.0 27905.0 35256.0 27559.0 36767.0 18241.3 True False 41642.5785532158 69095.64198707603 34912.49803864638 20979.827996202494 32243.011793819423 26711.56819973215 37081.38317106714 28839.491749075845 32625.913286325835 21394.2843999956 1.9464347474610726 3.229630900255315 1.6318609861357907 0.9806277042950223 1.5070853126466832 1.2485375860357193 1.7332378348244621 1.347999830696921 1.5249826858584972 1.0 14.384937803785764 -5.429482982107044 6.246881650979541 1.3645739671984822 2.5754305177028955 0.651215984377297 0.3610335080380089 0.12558487455796155 6.923279839085307 0.08758520051154509 0.18413099012752931 3.7197779688089394e-06 5.429482982107044 1.2108565505044133 NS(ph)PATPPNTLNLR ddPTM_PC-9_Lapatinib_30min_R1 2 NSPATPPNTLNLR 13 0 Q92870;Q92870-4;H0YAJ5;G5E9Y1;Q92870-2;D6RB55;D6RDY3;D6RB00 Q92870 APBB2 Amyloid beta A4 precursor protein-binding family B member 2 1 NS(0.887)PAT(0.098)PPNT(0.015)LNLR;NS(0.49)PAT(0.485)PPNT(0.025)LNLR 96.665 0.0032061999999999998 15776600.0 57739.0 52990.0 63447.0 47147.0 53528.0 50515.0 42794.0 46318.0 59011.0 43083.0 True False 56915.6312719642 52867.304910695886 58230.63257250255 50614.34765778143 50379.58828009708 48354.59120621641 45009.663927349844 48470.10337217225 52364.55976662153 50529.83914551101 1.1263766565348445 1.046259117478163 1.1524009091898262 1.0016724476804104 0.9970264923072236 0.9569512197925165 0.8907541501910446 0.9592372386659033 1.0363096469756625 1.0 15.624847966900072 -5.912135824399795 4.97771650405455 0.968920305145909 1.1015354161239996 0.6554983790925584 0.04365842759316485 0.130456297676369 5.534896422672876 0.012921110594125738 0.0194938465091196 1.2242332638149574e-06 5.912135824399795 0.13261511097809064 NS(ph)PEDLGLSLTGDSCK ddPTM_PC-9_AZD4547_30min_R2 7 NSPEDLGLSLTGDSCK 16 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 NS(1)PEDLGLSLTGDSCK;NS(1)PEDLGLSLTGDSCK;NS(1)PEDLGLSLTGDSCK;NS(1)PEDLGLSLTGDSCK;NS(0.993)PEDLGLS(0.007)LTGDSCK;NS(1)PEDLGLSLTGDSCK;NS(0.99)PEDLGLS(0.003)LT(0.006)GDSCK 190.8 1.9822999999999998e-08 85894000.0 160971.3 175930.4 163695.5 186130.40000000002 186027.4 209783.4 180993.8 199532.3 176537.3 168635.8 True False 212156.8249889617 232796.46129351662 161524.79071326047 143220.91196601355 160200.7065766614 196665.61083481563 197101.89756855 168699.16783111374 185868.70126995907 162731.91197074254 1.3037198569086144 1.4305519948378098 0.9925821478844352 0.880103418140648 0.9844455499635731 1.2085251654277496 1.2112061806536558 1.036669241995043 1.142177333376236 1.0 17.31213766784097 -5.260953550463692 24.999185070945302 1.0602884489628126 1.3671359437812327 0.5909353259970733 0.10319631395962177 31.4257762017625 1616948.7558908057 0.02979483419115827 0.06963469273366862 5.483356084768021e-06 5.260953550463692 0.3068474948184201 NS(ph)PEDLGLSLTGDSCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 NSPEDLGLSLTGDSCK 16 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 NS(0.992)PEDLGLS(0.003)LT(0.005)GDSCK;NS(1)PEDLGLSLTGDSCK;NS(0.996)PEDLGLS(0.003)LTGDSCK;NS(1)PEDLGLSLTGDSCK;NS(0.984)PEDLGLS(0.015)LT(0.001)GDSCK;NS(1)PEDLGLSLTGDSCK;NS(1)PEDLGLSLTGDSCK;NS(0.992)PEDLGLS(0.008)LTGDSCK 206.45 5.3406999999999993e-17 87336100.0 391278.4 526152.3 374397.0 457618.5 464944.2 340423.5 476273.2 328600.4 331040.5 345165.8 True False 457514.1050193334 578385.2231245895 383324.0443885303 431979.6190641948 373841.7216398656 322571.09237867873 431157.1545766363 319974.98768090253 335881.34104540385 407741.6272090298 1.122068669198663 1.4185091355121286 0.9401150601481714 1.0594444869930812 0.9168593459509953 0.7911164101312418 1.0574273652849344 0.7847493763909137 0.8237602408772784 1.0 18.637295726584192 -5.318405414622979 8.446351229196878 0.9184067062584063 1.2697264451385808 0.5932207370332117 0.11545060286434938 0.20871672674698305 29.23658240391012 0.029869206747565276 0.0625962954355787 4.8039069355884695e-06 5.318405414622979 0.35131973888017454 NS(ph)PEDLGLSLTGDSCK ddPTM_PC-9_Lapatinib_30min_R1 7 NSPEDLGLSLTGDSCK 16 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 NS(0.999)PEDLGLS(0.001)LTGDSCK;NS(1)PEDLGLSLTGDSCK;NS(1)PEDLGLSLTGDSCK;NS(1)PEDLGLSLTGDSCK;NS(0.976)PEDLGLS(0.008)LT(0.015)GDSCK;NS(1)PEDLGLSLTGDSCK;NS(0.998)PEDLGLS(0.002)LTGDSCK 211.67 1.029e-17 77998800.0 250077.1 414891.3 371950.8 358836.3 427062.5 431158.7 405514.7 442771.4 393858.4 355010.5 True False 246510.95469547683 413930.64468569506 341370.44099560956 385226.3185448058 401943.5233871796 412719.0474810199 426510.2669673345 463344.1756604639 349497.9194791804 416373.5919032427 0.592042721942753 0.9941327998099473 0.8198657350847014 0.9251939268865185 0.9653434588632211 0.9912229197689559 1.0243451440274036 1.1128087483707092 0.839385413185371 1.0 18.667519044422853 -4.434209131781091 2.213234218751323 0.9674233379308586 2.8400733045448894e-17 0.6282817383843923 0.08421234258904797 1.9966722636949827 4.078266652954015 0.02262827507698852 5.582055339343195 3.679517461213554e-05 4.434209131781091 -0.9674233379308586 NS(ph)PGSQVASNPR ddPTM_PC-9_AZD4547_30min_R2 5 NSPGSQVASNPR 12 0 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 NS(0.931)PGS(0.069)QVASNPR;NS(1)PGSQVASNPR;NS(0.6)PGS(0.4)QVASNPR;NS(0.996)PGS(0.004)QVASNPR;NS(0.99)PGS(0.01)QVASNPR 202.32 1.3794999999999999e-06 424252990.0 314384.8 304483.1 353730.5 431772.7 330608.1 345784.8 314304.1 360820.5 313257.3 371097.4 True False 414352.6267899289 402901.30758345313 349039.80244659755 332234.1748367169 284708.87202620495 324162.82179330883 342276.55601227825 305063.98255523655 329815.44135054667 358105.39297925786 1.1570689381210435 1.1250914269442178 0.9746845741214922 0.9277552959275331 0.7950421233748239 0.9052162523899353 0.955798384282092 0.8518832403423381 0.9210010455487617 1.0 18.4500247198918 -5.348950361470521 2.0247965967619086 0.8986391920861124 1.161220067152664 0.7544342385579226 0.052529862135003144 0.1621784331343978 1.234901476426196 0.014861698096434506 0.049841931866268 4.477644793606665e-06 5.348950361470521 0.2625808750665516 NS(ph)PGSQVASNPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 NSPGSQVASNPR 12 0 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 NS(0.993)PGS(0.007)QVASNPR;NS(0.912)PGS(0.034)QVAS(0.054)NPR;NS(1)PGSQVASNPR;NS(0.996)PGS(0.004)QVASNPR;NS(0.996)PGS(0.004)QVASNPR 187.08 5.6141000000000003e-05 407264000.0 336318.0 334791.0 313710.0 358473.0 416420.0 290392.0 346095.0 267498.0 253549.9 252192.2 True False 393249.9948167139 368026.83792336175 321190.03615180094 338388.9199951464 334825.4902959819 275163.3323141007 313310.3760891883 260476.4609375586 257257.58761821565 297912.64950764354 1.3200177819459267 1.2353514982717082 1.0781349388239394 1.135866236477026 1.123904912561933 0.9236376258908766 1.0516853735717244 0.874338371895402 0.8635336164589923 1.0 18.184529856817484 -5.253202122804882 0.419338513716053 0.907473826470645 1.487796301020619 0.7700796000019895 0.06846192975168416 1.757062900200732 0.32517356478923 0.05807750723719245 0.49126737821600214 5.58210340413034e-06 5.253202122804882 0.580322474549974 NS(ph)PGSQVASNPR ddPTM_PC-9_Lapatinib_30min_R1 5 NSPGSQVASNPR 12 0 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 NS(0.988)PGS(0.012)QVASNPR;NS(0.988)PGS(0.012)QVASNPR;NS(0.981)PGS(0.011)QVAS(0.008)NPR;NS(0.981)PGS(0.018)QVASNPR;NS(0.893)PGS(0.106)QVAS(0.001)NPR 182.7 8.5059e-05 421410350.0 171632.4 182075.6 173292.59999999998 180607.7 192186.90000000002 184891.3 179223.19999999998 189431.9 179561.1 143503.4 True False 169184.89050247287 181654.01513489176 159045.15135678084 193890.19274762578 180882.8443959831 176983.93010167114 188502.5003501473 198233.59762915084 159337.0380557915 168307.7714837386 1.0052113993964862 1.0792966571507523 0.9449661768716802 1.1519978610515849 1.074714749065877 1.051549364247692 1.1199869066554653 1.1778041850450358 0.9467004206112145 1.0 17.36074226799235 -5.762919872085067 24.999999670238722 1.0830131448292069 1.016771949034979 0.13891102762621155 0.0713032537486014 72.38677820696918 1222377.5777867192 0.019032892082186257 0.030016668637316116 1.7261563407743487e-06 5.762919872085067 -0.06624119579422794 NS(ph)PLLER ddPTM_PC-9_AZD4547_30min_R2 1 NSPLLER 7 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 NS(1)PLLER 73.781 0.035394999999999996 8224600.0 21822.0 31602.0 39840.0 48885.0 40678.0 40816.0 44749.0 47184.0 40606.0 40819.0 True False 28760.942074202798 41816.72848920779 39311.695569006435 37615.3185157211 35030.56185339064 38263.76906768521 48731.57430970028 39892.7969804551 42752.350261208005 39389.939234336656 0.7301595948929913 1.0616093678244538 0.9980136129465766 0.9549473608461776 0.8893276439191381 0.9714097003310491 1.2371578950601785 1.012766146785017 1.0853621785722456 1.0 15.265539570901284 -7.022481624816146 24.598687991863518 1.0876566211694878 0.9388740095148386 0.3519282752640679 0.10024196948452753 730.1739415891496 798931.4467279187 0.03690756267999665 0.0288327089234957 9.495511742654743e-08 7.022481624816146 -0.14878261165464923 NS(ph)PLLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSPLLER 7 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 NS(1)PLLER;NS(1)PLLER 84.65799999999999 0.019806999999999998 12984000.0 50009.0 73595.0 79848.0 76639.0 87895.0 62578.0 71022.0 66902.0 57490.0 42941.0 True False 58474.535977227155 80901.02522758936 81751.87914522635 72345.16529699034 70672.60570953676 59296.299517727035 64294.28200524789 65145.893388528384 58330.682489605475 50725.863379231014 1.1527558543472465 1.594867387919377 1.6116409598401928 1.4261987963838392 1.3932262755427571 1.1689559441191308 1.2674852180351903 1.2842737224892942 1.1499199541172944 1.0 15.630433895122012 -6.623926202790953 2.9271665036795973 1.1961636997019496 1.4664806712503338 0.464881927491293 0.13901198764820746 0.24767109275524818 4.278952049649229 0.049209404177844494 0.04937432787959049 2.3772442039905772e-07 6.623926202790953 0.2703169715483842 NS(ph)PLLER ddPTM_PC-9_Lapatinib_30min_R1 2 NSPLLER 7 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 NS(1)PLLER;NS(1)PLLER 84.31 0.020041 16019200.0 35523.0 64792.0 84688.0 73658.0 81254.0 70593.0 71640.0 65441.0 78169.0 52879.0 True False 35016.435505879635 64641.97810480865 77725.27954513354 79075.05503588478 76474.79947151044 67573.90195032043 75349.16866278787 68481.62776411587 69364.78406393784 62019.06469316151 0.5646076037928495 1.0422920504303632 1.2532481734395433 1.2750120535855798 1.2330853399655168 1.0895666080203144 1.2149355853006953 1.1042028463816376 1.118442924076962 1.0 15.920424148442384 -4.781281593363603 3.1830674938497663 1.1703294830526063 0.47548304893215526 0.8256212827305519 0.08187084002290364 0.13123017232024425 2.0169177342045708 0.021014133599976927 0.23034046408371767 1.6546967223217226e-05 4.781281593363603 -0.694846434120451 NS(ph)PPFLK ddPTM_PC-9_AZD4547_30min_R2 1 NSPPFLK 7 0 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 NS(1)PPFLK 102.06 0.010998 16156000.0 221700.0 226090.0 225080.0 287030.0 238570.0 288190.0 220960.0 251340.0 264770.0 259700.0 True False 292195.9883535305 299169.1710690775 222095.2921353404 220859.66806929384 205448.67351795555 270169.4337420661 240625.01194376097 212501.17821862517 278765.2016613322 250607.98204652753 1.1659484505137663 1.193773512822645 0.8862259307211791 0.8812954250926027 0.8198009969204103 1.078055980243705 0.9601649954592701 0.8479425774202695 1.112355637617229 1.0 17.935072840714895 -5.255430124636811 24.88829265442401 0.9408851630896121 1.179861013882187 0.509251245546583 0.09072465288406835 344.80495633799393 1428054.1750729291 0.02313349468715326 0.05788611398704222 5.553539630354333e-06 5.255430124636811 0.23897585079257488 NS(ph)PPFLK ddPTM_PC-9_Lapatinib_30min_R1 1 NSPPFLK 7 0 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 NS(1)PPFLK 72.321 0.039147 18961000.0 246120.0 318150.0 267730.0 285330.0 300340.0 294600.0 287670.0 283340.0 281320.0 238230.0 True False 242610.28366711998 317413.3432220783 245718.27286768696 306314.12003297755 282674.5916911588 282000.6447461422 302564.14501988 296505.01078352495 249634.77916906963 279407.7380784788 0.8683019494577373 1.1360220207391847 0.8794254395297768 1.096297912647435 1.0116920656354995 1.0092800102298354 1.0828767560292019 1.0611911209855038 0.8934426114532066 1.0 18.092012450563068 -4.726216641298215 24.605964857325137 1.020357711401289 0.868300438663623 0.24965704897708285 0.07829606918099749 6780.398645341234 4736312.920630693 0.018117575097212707 3.9261823103229454 1.878379581536558e-05 4.726216641298215 -0.1520572727376659 NS(ph)PQALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSPQALR 7 0 Q7L7X3;Q7L7X3-3 Q7L7X3 TAOK1 Serine/threonine-protein kinase TAO1 1 NS(1)PQALR 83.647 0.020712 24691000.0 22201.0 41376.0 31981.0 28824.0 34390.0 23841.0 25813.0 28546.0 24484.0 21670.0 True False 25959.190810262546 45483.53583554225 32743.548328617908 27209.084728668855 27651.526370680607 22590.735990318142 23367.80577006372 27796.697746987098 24842.032180822775 25598.59946037438 1.014086370250308 1.7767978246602503 1.2791148351418065 1.062913022674832 1.0801968448892714 0.8824989048829687 0.9128548538851182 1.0858679120322692 0.9704449737290222 1.0 14.643777259819833 -5.72034064475836 3.110509429238114 0.9916926372060674 1.4206185453995697 0.4529933305887386 0.18239489546671178 0.19355897068221203 3.8147921569295047 0.049547407880160696 0.08903891527964801 1.903966730035636e-06 5.72034064475836 0.4289259081935023 NS(ph)PQALR ddPTM_PC-9_Lapatinib_30min_R1 1 NSPQALR 7 0 Q7L7X3;Q7L7X3-3 Q7L7X3 TAOK1 Serine/threonine-protein kinase TAO1 1 NS(1)PQALR 72.096 0.039726 26452000.0 31302.0 86112.0 61861.0 76493.0 71819.0 69529.0 66309.0 67098.0 59138.0 58201.0 True False 30855.62773991622 85912.61295470569 56775.027370365526 82118.55039316749 67594.74762158675 66555.40675001535 69742.15556757122 70215.61803329176 52477.25568925222 68260.96530204217 0.4520244857860677 1.2585906538906715 0.8317349032371065 1.2030089236184702 0.9902401368409086 0.9750141454273311 1.0216989352402952 1.0286349998509488 0.7687740051294331 1.0 16.058773195782628 -4.744661317165017 24.994896859137242 1.00885692671483 0.45202285308785384 0.5932177778202394 0.13827527668153153 674.1404739373386 1004238.1835348003 0.03188462292227085 0.8876695541602673 1.8002743046439273e-05 4.744661317165017 -0.5568340736269761 NS(ph)PQALRR ddPTM_PC-9_AZD4547_30min_R2 1 NSPQALRR 8 1 Q7L7X3;Q7L7X3-3 Q7L7X3 TAOK1 Serine/threonine-protein kinase TAO1 1 NS(1)PQALRR 62.166000000000004 0.028887 31159000.0 27118.0 40229.0 47854.0 49837.0 60214.0 54354.0 41853.0 67863.0 57581.0 48499.0 True False 35740.9599105596 53232.23752902788 47219.42469275184 38347.84962397449 51854.32546929703 50955.235787557824 45577.83591999567 57376.33268660189 60624.61410605864 46801.064771946694 0.7636783497281305 1.1374150949004933 1.008939111168597 0.8193798540874396 1.107973199370014 1.0887623184612074 0.9738632260203565 1.2259621221480026 1.295368265689502 1.0 15.51425373251481 -7.066867453310721 0.9655472296650576 1.1716952694562792 0.9583150619428934 0.2745500269606036 0.13418598307740284 0.7567904994624792 1.437497843045506 0.09161775479047737 0.06214086326090872 8.572994531265205e-08 7.066867453310721 -0.21338020751338582 NS(ph)PQALRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NSPQALRR 8 1 Q7L7X3;Q7L7X3-3 Q7L7X3 TAOK1 Serine/threonine-protein kinase TAO1 1 NS(1)PQALRR;NS(1)PQALRR;NS(1)PQALRR;NS(1)PQALRR 93.556 0.0032714 42184500.0 56440.8 61686.0 56175.1 94734.0 110520.0 90788.0 100890.0 98592.3 107383.0 73178.8 True False 65995.11268338675 67809.77841142821 57514.527429253096 89426.36111177182 88864.39937445834 86026.91745686023 91332.96881965414 96004.35659217685 108953.27322632316 86445.53715693814 0.7634299566393516 0.7844219683466422 0.6653267400587488 1.0344821034476555 1.0279813429018188 0.9951574168679417 1.056537697878412 1.1105762049680492 1.260368976926168 1.0 16.399503864669192 -5.819840944695218 6.382016683064515 1.0706474188283033 0.7428823982928626 0.7958198672797784 0.07702284088362532 0.08932992132147093 7.266403663511435 0.02302153678628321 0.0347825266024252 1.5141156741662016e-06 5.819840944695218 -0.32776502053544065 NS(ph)PQALRR ddPTM_PC-9_Lapatinib_30min_R1 1 NSPQALRR 8 1 Q7L7X3;Q7L7X3-3 Q7L7X3 TAOK1 Serine/threonine-protein kinase TAO1 1 NS(1)PQALRR 80.737 0.008652799999999999 28928000.0 69435.0 55920.0 57411.0 51492.0 61917.0 64379.0 63216.0 37922.0 56366.0 16957.0 True False 68444.84416718049 55790.520675714586 52690.88919286876 55278.89345227651 58275.16379350563 61625.66024477891 66489.01516173642 39683.99456106729 50017.467519706326 19887.994856217778 3.441515580731454 2.805236077294753 2.6493816784347914 2.7795106470974438 2.9301678834297613 3.0986361717361506 3.3431733888924104 1.9953743375320963 2.514957786408964 1.0 14.279610207917425 -8.741264638482901 0.8829039423107182 1.011235716263725 2.9641714011972637 0.7441889316523651 0.34290688896777727 0.44686196699217323 0.6997452617867886 0.3330845507992788 0.11363183735012283 1.8144097105285871e-09 8.741264638482901 1.9529356849335386 NS(ph)PSAASTSSNDSK ddPTM_PC-9_AZD4547_30min_R2 1 NSPSAASTSSNDSK 14 0 D6RA28;A0A590UJ84;B1AKN3;Q9P2R6-2;Q9P2R6 D6RA28 RERE Arginine-glutamic acid dipeptide repeats protein 1 NS(0.959)PS(0.04)AASTSSNDSK 157.83 1.4728e-12 0.0 8987.6 9336.9 7148.8 7266.6 7162.2 10431.0 11199.0 9345.3 9947.6 9005.4 True False 11845.469846306703 12354.87033196899 7054.00224105706 5591.397637850855 6167.852158571088 9778.747921036462 12195.689304662306 7901.198618630193 10473.409827572104 8690.123687030426 1.363095655817359 1.4217139797915668 0.8117263338362842 0.6434197992136448 0.7097542429432044 1.1252714314792496 1.4033965158474973 0.9092158987820088 1.2052083727189227 1.0 13.085160995809417 -6.962462480825756 24.99241124686185 1.1422397262783066 0.9780507584271443 0.06229546602338465 0.2652209462736934 513.870286085987 342132.5510203681 0.1046842902148206 0.09232263677176722 1.0902786786815311e-07 6.962462480825756 -0.16418896785116233 NS(ph)PSAASTSSNDSK ddPTM_PC-9_Lapatinib_30min_R1 1 NSPSAASTSSNDSK 14 0 D6RA28;A0A590UJ84;B1AKN3;Q9P2R6-2;Q9P2R6 D6RA28 RERE Arginine-glutamic acid dipeptide repeats protein 1 NS(0.996)PS(0.004)AASTSSNDSK 128.82 2.4494e-05 6551500.0 2813.9 11401.0 8981.7 8581.1 8336.0 7577.9 11950.0 10708.0 8488.8 8443.4 True False 2773.773269993939 11374.601684975349 8243.259296364628 9212.182719710441 7845.692869206565 7253.810881947685 12568.712528200933 11205.53277147588 7532.70195297312 9902.83043987669 0.2800990370212254 1.148621270861322 0.8324144643707817 0.9302575436023673 0.7922677174814132 0.7324987462915712 1.2692040527715467 1.1315484839923615 0.7606615097276084 1.0 13.273625221768262 -7.238323881582133 24.846894415595106 1.0513159349975272 0.8114562379229516 0.21277836072056588 0.23626300701433098 1205.649233948904 1295956.3797068533 0.087513796443438 0.06774384559870296 5.7766508438157206e-08 7.238323881582133 -0.23985969707457555 NS(ph)PSNLSSSSDTGSVGGTYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSPSNLSSSSDTGSVGGTYR 20 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 NS(0.93)PS(0.067)NLS(0.001)SSSDT(0.001)GS(0.001)VGGTYR;NS(0.792)PS(0.208)NLSSSSDTGSVGGTYR 285.76 1.1022999999999998e-106 8069000.0 16101.8 21524.0 23605.0 19266.3 23313.0 14108.7 22803.0 13911.4 14847.8 13841.3 True False 18827.51671495364 23660.76047283958 24167.832722461004 18186.87167318736 18744.985003770784 13368.814935053137 20642.934760576565 13546.240490346687 15064.92098572212 16350.618122329486 1.1514865416153006 1.4470866052780524 1.4780990260824336 1.112304839922239 1.14643892136233 0.8176336108538795 1.262517086885248 0.8284849165333416 0.9213670622732278 1.0 13.997057556261371 -6.111781487126213 1.9800108176462887 0.9811957209787169 1.3624487860249863 0.5257790186369853 0.15203497328217014 0.2536928248101289 1.9663602077124676 0.04940881631034847 0.07208247546895791 7.730694528915254e-07 6.111781487126213 0.38125306504626943 NS(ph)RDGDPLPSSLSCK ddPTM_PC-9_AZD4547_30min_R2 1 NSRDGDPLPSSLSCK 15 1 H3BP35;P53602 H3BP35 MVD Diphosphomevalonate decarboxylase 1 NS(0.977)RDGDPLPS(0.018)S(0.005)LSCK 148.97 0.00063281 14523000.0 56569.0 51254.0 60252.0 67203.0 65642.0 62938.0 55422.0 63211.0 60836.0 65337.0 True False 74556.76529170465 67820.85317340224 59453.019112042566 51710.386625999956 56528.741363397115 59002.47691057359 60354.450633359585 53443.192394276644 64051.666760844484 63049.57151703507 1.182510261335567 1.0756750845654526 0.9429567510380183 0.8201544496147538 0.8965761384773865 0.9358109102237434 0.957253938150122 0.8476376779156553 1.0158937677084556 1.0 15.944198945624766 -5.092573680316152 2.446523371395901 0.9168004755338572 1.1794848772000759 0.6753164253251356 0.0581510346081337 0.17971900394445528 1.9128548974327055 0.015387208924816442 0.07373348968639588 8.080278313617826e-06 5.092573680316152 0.26268440166621865 NS(ph)RDGDPLPSSLSCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSRDGDPLPSSLSCK 15 1 H3BP35;P53602 H3BP35 MVD Diphosphomevalonate decarboxylase 1 NS(1)RDGDPLPSSLSCK 116.0 0.00072977 5265000.0 28857.0 26663.0 26460.0 34223.0 35610.0 25095.0 30412.0 29537.0 22750.0 22576.0 True False 33741.92014827018 29309.926430371783 27090.906750108807 32305.596262463027 28632.476128523904 23778.974022777318 27531.155196187112 28761.6850470384 23082.67571122847 26668.850088482337 1.2652184116045762 1.0990322542264417 1.0158258290187303 1.2113606756676423 1.0736299478052715 0.8916385199917903 1.0323337941022506 1.0784748855542112 0.8655294710737208 1.0 14.702867999436062 -6.530649696314187 21.453342544686848 0.9822224349096275 1.1358850363390702 0.48162291113248723 0.08491787374564379 31.616788020123067 87280.49150346323 0.027801070931641376 0.02789254906175467 2.94679757429148e-07 6.530649696314187 0.15366260142944277 NS(ph)RDGDPLPSSLSCK ddPTM_PC-9_Lapatinib_30min_R1 2 NSRDGDPLPSSLSCK 15 1 H3BP35;P53602 H3BP35 MVD Diphosphomevalonate decarboxylase 1 NS(0.985)RDGDPLPS(0.011)S(0.003)LSCK;NS(0.996)RDGDPLPS(0.001)S(0.002)LSCK 112.16 0.0016768 19419100.0 52095.0 77151.0 79250.0 78216.0 74749.0 81835.0 78217.0 72113.0 81493.0 72023.0 True False 51352.115746947034 76972.36159964322 72734.37091384667 83968.26556092728 70352.4107821883 78335.10781670238 82266.69354127976 75463.63324144957 72314.40018066605 84472.07958538509 0.6079182139116143 0.9112166052670565 0.8610462921103552 0.994035733144837 0.8328480975903463 0.9273491099212325 0.9738921303354903 0.8933559302890169 0.8560745815138842 1.0 16.366186948164177 -4.7613126943425605 8.530256605531758 0.9136760693962814 0.6050885300810337 0.7359164829559176 0.05545848169894034 0.04283611872362324 34.55631313792901 0.013124911780123021 0.07599359157555972 1.7325560989321963e-05 4.7613126943425605 -0.30858753931524774 NS(ph)S(ph)VALS(ph)T(ph)CQGLSGMIR ddPTM_PC-9_AZD4547_30min_R2 1 NSSVALSTCQGLSGMIR 17 0 Q2XQZ0;Q8TE57-2;Q8TE57 Q2XQZ0 ADAMTS16 A disintegrin and metalloproteinase with thrombospondin motifs 16 4 NS(1)S(1)VALS(0.997)T(0.997)CQGLS(0.006)GMIR 54.7 0.035781 0.0 5522.4 4539.7 4980.1 7062.3 6496.3 5395.7 5372.0 5048.6 3570.5 5324.7 True False 7278.4083269442535 6007.069246327969 4914.060620060463 5434.195846447316 5594.4008793003995 5058.306026031676 5850.097593057051 4268.454875286657 3759.229340679782 5138.283873712544 1.416505686690567 1.169080843715181 0.9563622292650652 1.0575896505540805 1.0887683547266336 0.9844349106342617 1.138531411817503 0.8307160484308912 0.7316118441629892 1.0 12.327070881378852 -1.5228787452803376 0.5697206213320192 0.9475711467462102 24.15460363055088 0.6075112696303944 0.11230256848724124 111.12318896285795 0.9547918273424894 0.05778757324557301 3178.832769348677 0.029999999999999995 1.5228787452803376 23.20703248380467 NS(ph)SDQEGNNISSSSGHR ddPTM_PC-9_AZD4547_30min_R2 1 NSSDQEGNNISSSSGHR 17 0 Q8IWI9-3;Q8IWI9;H3BP52;H3BTF4 Q8IWI9-3 MGA MAX gene-associated protein 1 NS(0.5)S(0.5)DQEGNNISSSSGHR 79.029 0.017976 0.0 1177.2 2298.2 3606.9 6417.0 3557.1 4041.7 2248.3 3540.4 2462.6 3486.6 True False 1551.5251127188865 3041.048206249517 3559.0701492934077 4937.659791661706 3063.2580650153864 3788.9718600760307 2448.394344465777 2993.312530298475 2592.7680085024585 3364.535195238445 0.4611409965081164 0.9038538846475042 1.0578192655943301 1.4675607491488207 0.9104550516667409 1.126150163457424 0.7277065634298586 0.8896659884951326 0.7706169970139691 1.0 11.716191497419969 -7.263633890397802 24.982508428194595 0.8378028919702003 1.005483147300143 0.07120408506899778 0.2433342110761851 525.963845523465 5987564.95763068 0.10309886394855258 0.07342663845780387 5.449618612976053e-08 7.263633890397802 0.1676802553299428 NS(ph)SEASSGDFLDLK ddPTM_PC-9_AZD4547_30min_R2 1 NSSEASSGDFLDLK 14 0 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 NS(0.795)S(0.205)EAS(0.001)SGDFLDLK 136.66 5.8971e-05 9995900.0 14109.0 13306.0 13604.0 8965.4 10711.0 19240.0 16162.0 16205.0 14262.0 10957.0 True False 18595.368514569112 17606.904286988112 13423.602071304304 6898.565544049215 9223.962535318047 18036.919758483506 17600.386690057338 13700.889603854592 15015.860203549935 10573.398765051244 1.7586935788360942 1.6652076289021698 1.2695635877910867 0.6524454148888595 0.8723744124553826 1.7058771885253954 1.664591214343748 1.2957886019716565 1.4201545347161755 1.0 13.368151577775878 -6.780709427392889 24.99991489830521 1.4512257510718383 1.2356703639886606 0.05171522944679163 0.3564327405010165 777.2460695300815 1008350.1821444859 0.13967299301267466 0.12336368594485532 1.6568781571089129e-07 6.780709427392889 -0.21555538708317767 NS(ph)SEASSGDFLDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NSSEASSGDFLDLK 14 0 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 NS(0.84)S(0.158)EAS(0.001)SGDFLDLK;NS(0.798)S(0.202)EASSGDFLDLK;NS(0.981)S(0.019)EASSGDFLDLK;NS(0.5)S(0.5)EASSGDFLDLK 169.49 0.00017426 30856500.0 83255.9 150985.0 95661.0 87352.1 98711.2 68138.5 108928.6 66764.5 75421.1 73935.3 True False 97349.47949102016 165973.79297489728 97941.92103636284 82458.04503632942 79369.4489642781 64565.19710902623 98610.09443322974 65012.002617835045 76523.99090479703 87339.18461848723 1.1146140179377635 1.9003359568777718 1.1213972452821743 0.9441128331632649 0.9087495986020213 0.73924662098757 1.1290475731365688 0.7443623718473993 0.8761702005699635 1.0 16.414341442012294 -5.488362006744223 5.490428077941336 0.9054695286149805 1.5148129493199471 0.571642116047097 0.20618079707038864 0.11693817371841338 9.622613555485632 0.051165479814171994 0.10407596960787073 3.2481643334064447e-06 5.488362006744223 0.6093434207049666 NS(ph)SEASSGDFLDLK ddPTM_PC-9_Lapatinib_30min_R1 1 NSSEASSGDFLDLK 14 0 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 NS(0.714)S(0.284)EAS(0.002)S(0.001)GDFLDLK 102.57 0.0014277 54132000.0 45179.0 84403.0 61070.0 66378.0 85484.0 84760.0 96648.0 91968.0 76178.0 81573.0 True False 44534.73917518611 84207.57003920466 56049.06033701723 71259.65955051668 80455.99918801029 81135.01238521039 101651.96053770406 96241.16902569053 67598.03145009727 95672.78436080973 0.46549015451701214 0.8801622175187623 0.5858412160938059 0.7448268598703671 0.8409496987626852 0.848046943833335 1.0624961029078566 1.0059409232069305 0.7065544491228096 1.0 16.545820965161695 -6.385815796507648 1.4362543368769014 0.9395171279659295 0.6623377436121052 0.46305481853693875 0.13297129803391927 0.38195681443197 1.593647205894988 0.05122449246812265 0.06382432756052797 4.113241448682608e-07 6.385815796507648 -0.2771793843538243 NS(ph)SEKLPTELSK ddPTM_PC-9_AZD4547_30min_R2 1 NSSEKLPTELSK 12 1 P38432 P38432 COIL Coilin 1 NS(0.94)S(0.046)EKLPT(0.014)ELSK 71.98 0.012322 22612000.0 88863.0 117940.0 118250.0 100410.0 106870.0 131990.0 111200.0 113880.0 102050.0 134260.0 True False 117119.58553477589 156061.7985575966 116681.92773682249 77262.02581903564 92032.94521047879 123736.64443462781 121096.58457705592 96282.46270206485 107444.15466079574 129559.59826556375 0.9039823147236915 1.2045560548722154 0.9006042724650523 0.5963435118150677 0.7103521965376506 0.9550557896991901 0.9346786050450633 0.7431519083959387 0.8293029316173314 1.0 16.983256374224865 -5.512948405978287 24.62567853880421 0.813340044008179 1.0538469759594913 0.31615906118499226 0.1333027235912187 407.83451467113395 1011363.3236462125 0.036138735168536266 0.06782089789669518 3.0693866087113153e-06 5.512948405978287 0.24050693195131223 NS(ph)SEKLPTELSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSSEKLPTELSK 12 1 P38432 P38432 COIL Coilin 1 NS(0.947)S(0.053)EKLPTELSK;NS(0.647)S(0.353)EKLPTELSK 69.431 0.015174000000000002 23646400.0 168715.0 158056.0 142348.0 177961.0 192980.0 146040.0 189308.0 153865.0 132303.0 150716.0 True False 197275.11722685676 173746.75512428617 145742.11617779595 167990.4221273465 155166.95431852152 138381.40531127297 171375.3757687688 149826.20678344308 134237.68108231478 178039.61773280078 1.108040557146805 0.97588816094316 0.818593737920307 0.9435564076500325 0.8715304845879516 0.7772506314799762 0.962568769530647 0.8415329615473565 0.753976462046648 1.0 17.44183878274592 -4.925698525312099 2.7922369682497044 0.868077913893537 1.119506835213044 0.48892165658827846 0.0755960758914102 0.26207455582329425 3.4852887690578855 0.018963209498906747 0.13120899860946825 1.1865921603512491e-05 4.925698525312099 0.251428921319507 NS(ph)SEKLPTELSK ddPTM_PC-9_Lapatinib_30min_R1 1 NSSEKLPTELSK 12 1 P38432 P38432 COIL Coilin 1 NS(0.972)S(0.027)EKLPT(0.001)ELSK 68.97800000000001 0.015681 26706000.0 151700.0 138030.0 119310.0 110940.0 137360.0 109260.0 110830.0 119710.0 122660.0 107970.0 True False 149536.73018162732 137710.40001553763 109500.7923499183 119098.89768499127 129280.75486015045 104587.20449749992 116568.23510464514 125272.16362284066 108844.73913293786 126632.47063901849 1.180871931401388 1.0874809542972446 0.8647133851006022 0.9405083631709075 1.0209131529043702 0.825911426743293 0.9205240529258669 0.9892578340348775 0.8595326189537378 1.0 16.950287857271242 -5.0733605648887545 3.959797985306406 0.9276611932098134 1.1663482398289118 0.6560087629252903 0.061370294907454735 0.12230121567488597 3.5836118945869644 0.015476453619956624 0.05170844336585621 8.445773594117906e-06 5.0733605648887545 0.23868704661909834 NS(ph)SIVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSSIVGR 7 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GUE9;Q96N67-7;A0A0U1RQT6 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 NS(0.5)S(0.5)IVGR;NS(0.5)S(0.5)IVGR 88.177 0.017446 9265600.0 53699.0 50097.0 56445.0 55438.0 69081.0 52640.0 48320.0 52837.0 42824.0 38678.0 True False 62789.18009640507 55070.29908046113 57790.86286885455 52331.988592421025 55545.07395210781 49879.46573257611 43742.779793494745 51450.08473542905 43450.21998495157 45690.01522512047 1.3742429234710223 1.205302708023248 1.2648466537844576 1.1453703469910157 1.2156939252138617 1.0916929111713727 0.9573815981012164 1.12606845241631 0.9509784527509315 1.0 15.479591302840003 -6.008903082346243 0.4207028346653075 0.9788810434356617 1.392760608859707 0.7590613670291884 0.06422841357526414 1.0088878121995501 0.28645422567428847 0.05739555523291076 0.19052564544392234 9.797085939067065e-07 6.008903082346243 0.41387956542404536 NS(ph)SSPVSLDAALPESSNVYR ddPTM_PC-9_Lapatinib_30min_R1 1 NSSSPVSLDAALPESSNVYR 20 0 Q70EL1-7;Q70EL1;H7C296;R4GN32;H7C1E9;Q70EL1-6 Q70EL1-7 USP54 Inactive ubiquitin carboxyl-terminal hydrolase 54 1 NS(0.464)S(0.464)S(0.069)PVS(0.002)LDAALPESSNVYR 155.53 1.9828e-05 3618600.0 3573.9 6996.3 6285.5 7729.2 9472.0 7259.3 8707.4 8906.1 8915.7 8299.9 True False 3522.9355306270104 6980.100497201389 5768.730452731651 8297.631151855354 8914.875582668497 6948.836661254816 9158.226566364587 9319.909919316531 7911.519979516828 9734.52665607842 0.36190106156083346 0.7170457017386546 0.5926051318714658 0.8523918465695667 0.9157995963883753 0.7138340575518207 0.9407983448939471 0.9574076119558422 0.8127277533907339 1.0 13.248895113886968 -4.5549948877074895 0.5717147378134596 0.9093408530077025 3.0853452525418546e-18 0.7263875633166874 0.09762570844350482 2.6546056530805417 0.5475954695183791 0.050181601341349275 1.6935426975601635 2.7861539656161724e-05 4.5549948877074895 -0.9093408530077025 down NS(ph)STEIR ddPTM_PC-9_Lapatinib_30min_R1 1 NSSTEIR 7 0 Q9UHB6;Q9UHB6-4;F8VRN8;F8VTU2;F8VVQ7 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 NS(0.333)S(0.333)T(0.333)EIR 86.13600000000001 0.018816 5735900.0 10044.0 10803.0 11455.0 12504.0 13261.0 18088.0 14158.0 17882.0 24353.0 15113.0 True False 9900.77071815598 10777.986317234348 10513.214117578713 13423.585872121212 12481.01405212911 17314.418405187433 14891.031964373951 18712.863001450478 21610.108691541132 17725.26191319333 0.5585683735813575 0.6080579440810427 0.593120382032464 0.7573138235057457 0.7041370735875669 0.976821583228618 0.840102224570809 1.055717150645997 1.2191700634593285 1.0 14.113519324818103 -6.798890767192936 0.6778748981648718 1.1084179056535164 0.5634067165943021 0.837238618081649 0.08587744879205976 0.2760395150156224 0.2769731749306403 0.06463582203956368 0.064747378390997 1.5889463466848572e-07 6.798890767192936 -0.5450111890592143 NS(ph)T(ph)FS(ph)AS(ph)GET(ph)VERK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSTFSASGETVERK 14 1 B1AQN8;A0A087WYK2;Q9BYP7-3;Q9BYP7-4;Q9BYP7-2;Q9BYP7 B1AQN8 WNK3 Serine/threonine-protein kinase WNK3 5 NS(1)T(1)FS(1)AS(1)GET(1)VERK 41.202 0.045891 0.0 5207.3 10171.0 8965.4 10449.0 12551.0 13360.0 12156.0 14641.0 14247.0 9794.2 True False 6088.7930411368925 11180.709662202726 9179.169137468834 9863.576406115066 10091.721648107372 12659.378081064164 11004.495678181336 14256.689263421787 14455.335422324053 11569.810929155463 0.5262655611591177 0.9663692631335731 0.7933724408873176 0.8525270176420295 0.8722460297667125 1.094173289311326 0.9511387649776061 1.232231827358172 1.2494011795730544 1.0 13.49807766803992 -6.64153865281983 0.7297625556064573 1.1660157440092374 0.7433329482429151 0.5908670870212778 0.12988504063555972 0.49124720238870706 0.5813972230240501 0.08726280963941063 0.09916495581859258 2.2827657462750484e-07 6.64153865281983 -0.4226827957663223 NS(ph)TELAPPLPVR ddPTM_PC-9_AZD4547_30min_R2 2 NSTELAPPLPVR 12 0 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 NS(0.993)T(0.007)ELAPPLPVR;NS(0.996)T(0.004)ELAPPLPVR 151.22 0.00018484 34741000.0 34502.0 53397.0 48082.0 40975.0 42005.0 59121.0 60120.0 64978.0 52460.0 56190.0 True False 45472.91831381837 70656.5360147531 47444.40126377932 31528.846807439353 36173.330809078 55424.15452397628 65470.56353212767 54937.14314589715 55232.928500787355 54222.80520290492 0.8386308702335861 1.3030778424382914 0.8749897960136807 0.5814683819742736 0.6671239282754787 1.022155794348445 1.2074359356203166 1.0131741236979372 1.0186291228220763 1.0 15.72661213211333 -6.978119819142939 24.538243975850737 1.0686060005937068 0.8622343313408349 0.22583915411577138 0.1848002515441244 330.8846083298084 371079.67242749577 0.07270663706085026 0.06411631132418696 1.0516716841260533e-07 6.978119819142939 -0.20637166925287187 NS(ph)TELAPPLPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NSTELAPPLPVR 12 0 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 NS(0.999)T(0.001)ELAPPLPVR;NS(0.996)T(0.004)ELAPPLPVR;NS(0.999)T(0.001)ELAPPLPVR;NS(0.969)T(0.031)ELAPPLPVR 157.5 5.6421e-05 30003800.0 49410.5 107497.0 79695.0 68954.0 89723.0 51158.299999999996 78717.0 50492.5 56936.9 47492.6 True False 57774.72174814098 118168.59173707647 81595.23104497042 65090.73093188429 72142.42223194477 48475.46868895993 71260.35589827229 49167.12537622597 57769.4944484679 56102.63242878528 1.0298041151897497 2.1062931741585484 1.454392200732195 1.160208142006673 1.2859008411685466 0.8640498064060185 1.2701784713707989 0.87637822411697 1.029710941314536 1.0 15.775780845621544 -5.771635724236047 2.729124729248133 1.0598170468639854 1.6097165690452153 0.37421711305090277 0.27573299021205416 0.24826711963178033 3.774964923336484 0.07673033107970637 0.1360725830407801 1.6918594276481686e-06 5.771635724236047 0.54989952218123 NS(ph)TELAPPLPVR ddPTM_PC-9_Lapatinib_30min_R1 3 NSTELAPPLPVR 12 0 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 NS(0.77)T(0.23)ELAPPLPVR;NS(0.997)T(0.003)ELAPPLPVR;NS(0.996)T(0.004)ELAPPLPVR 144.88 0.0001028 30152000.0 23058.600000000002 59534.1 42125.0 43054.9 61312.1 63073.4 72968.0 78934.7 64559.0 50271.9 True False 22729.78013557066 59396.2524492142 38661.64510720241 46221.30097293601 57705.84282222646 60375.89771327668 76745.92600483402 82602.29432728949 57287.68558359149 58961.330931903874 0.3855031726102305 1.0073763856825522 0.6557118792290128 0.7839256720021859 0.9787065846405772 1.0239914323339567 1.3016315064778656 1.4009570852918711 0.9716145256245093 1.0 15.847481470250848 -6.520579094165614 1.4164051967413935 1.1942331281924101 0.7073163148194963 0.5442443824108978 0.18762334463253924 0.305175642793899 1.2588788282842693 0.07602110761884533 0.08460133393606281 3.0159275592591075e-07 6.520579094165614 -0.4869168133729138 NS(ph)TELAPPLPVRR ddPTM_PC-9_AZD4547_30min_R2 1 NSTELAPPLPVRR 13 1 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 NS(0.762)T(0.238)ELAPPLPVRR 120.32 9.831e-05 9675000.0 19580.0 16350.0 21588.0 28918.0 27771.0 27862.0 24373.0 30242.0 22783.0 23239.0 True False 25806.03271069977 21634.817758323734 21301.729014651384 22251.401878646273 23915.47601235342 26119.784735492067 26542.149783242636 25568.79379202533 23987.262867583646 22425.4096834011 1.1507496663394714 0.9647457087188669 0.9498925243902481 0.9922405963943828 1.0664454451440966 1.1647405824128814 1.1835748001022552 1.1401706436137446 1.0696465842199798 1.0 14.452846721118165 -6.506497212419292 4.290819629415586 1.124726423815422 1.0075124169408138 0.28446452660422583 0.07064669527701964 0.22850772357092228 10.064840323322851 0.023296700617594517 0.025025143074523068 3.1153208920384286e-07 6.506497212419292 -0.11721400687460815 NS(ph)TELAPPLPVRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSTELAPPLPVRR 13 1 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 NS(0.925)T(0.075)ELAPPLPVRR;NS(0.751)T(0.249)ELAPPLPVRR 75.968 0.0081444 15452000.0 31883.0 34248.0 31762.0 39772.0 45650.0 42749.0 53512.0 42498.0 38926.0 37778.0 True False 37280.16218204589 37647.91510285309 32519.326538055775 37543.70378256374 36705.21020126696 40507.16718468651 48442.95596666988 41382.47253035306 39495.219109243066 44626.852349516565 0.8353751210161193 0.8436157407651208 0.7286941566786986 0.8412805700147132 0.8224915778014664 0.9076859570429756 1.0855113774833518 0.9272998285033954 0.8850101907236778 1.0 15.445624432612732 -6.881631719499349 3.6057246445754365 0.9715221938639497 0.8120703155759725 0.6316748949518001 0.05760306329862474 0.15915643901374849 3.980678226566088 0.021927431127145503 0.01920913247211063 1.3133131127817548e-07 6.881631719499349 -0.15945187828797713 NS(ph)TELAPPLPVRR ddPTM_PC-9_Lapatinib_30min_R1 1 NSTELAPPLPVRR 13 1 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 NS(0.782)T(0.218)ELAPPLPVRR 79.346 0.006408499999999999 6864100.0 21838.0 18955.0 17169.0 13000.0 21650.0 20586.0 21216.0 19781.0 20529.0 16311.0 True False 21526.58611540128 18911.11086209174 15757.431094256573 13956.063366728718 20376.589565537695 19705.584768309844 22314.460669314733 20700.097474090817 18216.80784004632 19130.334616958662 1.1252592569038697 0.9885405164490649 0.8236882108840858 0.7295253139146319 1.065145486136675 1.0300700517199126 1.1664438242252912 1.082056215354466 0.9522472139038007 1.0 14.22357448825725 NS(ph)TGSGHSAQELPTIR ddPTM_PC-9_AZD4547_30min_R2 1 NSTGSGHSAQELPTIR 16 0 I3L280;O94763-2;O94763-4;O94763-3;O94763 I3L280 URI1 Unconventional prefoldin RPB5 interactor 1 1 NS(0.809)T(0.147)GS(0.044)GHSAQELPTIR 70.47 0.011163 4568500.0 6044.4 5189.2 11485.0 12326.0 17128.0 13495.0 7831.4 12626.0 12324.0 11497.0 True False 7966.393468669752 6866.507419663218 11332.701395834312 9484.431134801649 14750.07285080081 12651.155516670227 8528.37942856794 10674.941816616363 12975.421480055344 11094.49352941445 0.7180493140627578 0.6189113005887363 1.021470819356315 0.8548773415979649 1.3294949257209847 1.1403094231502007 0.7687038084214425 0.962183788589741 1.1695370722110074 1.0 13.437556188654456 -5.2671765888444675 23.960913462767166 1.0284036221650232 0.668480290059888 0.47642247782796265 0.15192332755133475 211.7886598521114 884522.7438207146 0.041618225923042186 0.09075842156489164 5.405344910716697e-06 5.2671765888444675 -0.3599233321051353 NS(ph)TGSGHSAQELPTIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSTGSGHSAQELPTIR 16 0 I3L280;O94763-2;O94763-4;O94763-3;O94763 I3L280 URI1 Unconventional prefoldin RPB5 interactor 1 1 NS(0.54)T(0.36)GS(0.1)GHSAQELPTIR 61.56100000000001 0.023219 3580900.0 5772.0 7830.4 12515.0 12048.0 16097.0 15656.0 13074.0 17795.0 12304.0 8665.3 True False 6749.085597803499 8607.750362689234 12813.405063401799 11372.989620143013 12942.908403281364 14834.971799187157 11835.536072436882 17327.900105361008 12483.922723118907 10236.250295522941 0.6593318259084937 0.8409085469953809 1.2517674630334152 1.1110503643230814 1.2644189063003122 1.4492584072192503 1.1562374630105934 1.6927976168128442 1.219579666646002 1.0 13.32139970907099 -4.753225416302895 0.8314905184109377 1.3312709809467902 0.1958229413267005 0.5614431861903565 0.18384786465618075 1.7108421392555768 0.8812407329441512 0.06527237459294673 1.817275983473933 1.76512141387594e-05 4.753225416302895 -1.1354480396200897 NS(ph)TGSGHSAQELPTIR ddPTM_PC-9_Lapatinib_30min_R1 1 NSTGSGHSAQELPTIR 16 0 I3L280;O94763-2;O94763-4;O94763-3;O94763 I3L280 URI1 Unconventional prefoldin RPB5 interactor 1 1 NS(0.661)T(0.129)GS(0.209)GHS(0.002)AQELPTIR 72.585 0.009076299999999999 2282700.0 5779.1 7037.0 11528.0 6594.3 11218.0 14155.0 9926.0 10396.0 19720.0 13483.0 True False 5696.688974242856 7020.706258851994 10580.212339366873 7079.2668199399395 10558.179295436577 13549.623646916625 10439.919711708992 10879.036112463886 17498.92593919398 15813.518585031801 0.3602417098769546 0.4439686348803741 0.6690612391211602 0.4476718310269531 0.6676679347903233 0.8568380006042391 0.6601895495662072 0.6879579679857826 1.1065801608351409 1.0 13.948870789648629 -5.660710282662667 0.21995302303310413 1.080876930510253 0.009106235547668104 0.7173234779838542 0.1220880832782962 4.637958206600213 0.29242223475060225 0.2543582741567091 1.3755173046362423 2.1841864941843712e-06 5.660710282662667 -1.071770694962585 down NS(ph)TSIEPR ddPTM_PC-9_Lapatinib_30min_R1 1 NSTSIEPR 8 0 E7EN19 E7EN19 MAP4K4 1 NS(0.333)T(0.333)S(0.333)IEPR 89.171 0.010425 3304100.0 20597.0 16858.0 19901.0 15860.0 20969.0 20771.0 22347.0 18723.0 17883.0 13991.0 True False 20303.283002972796 16818.966336752434 18264.816600081533 17026.397307409035 19735.644646640187 19882.672749565892 23504.018315289217 19592.938931671935 15868.82822366156 16409.325708164346 1.2373014811249092 1.0249638916231807 1.1130753892583167 1.0376049333299338 1.2027090568883554 1.211669090075615 1.4323573517463277 1.1940124341564873 0.9670615664460932 1.0 14.002228336409958 -4.448334824254511 19.941317809041507 1.1471780040941637 4.000174774795154 0.04347565780827656 0.13151895439297573 557.2270764983293 154757.88211304616 0.033500891807144655 2699.6781410251774 3.5617642929050854e-05 4.448334824254511 2.8529967707009902 NS(ph)TSSIEPR ddPTM_PC-9_AZD4547_30min_R2 2 NSTSSIEPR 9 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6 C9J840;O95819-6 MAP4K4 1 NS(0.73)T(0.024)S(0.202)S(0.043)IEPR;NS(0.971)T(0.006)S(0.019)S(0.004)IEPR 94.12200000000001 0.005849 24941400.0 47869.0 57953.0 71722.0 82918.0 76859.0 75557.0 64881.0 71021.0 52863.0 72799.0 True False 63090.34626294624 76685.17391731722 70770.91941767764 63802.53617032957 66188.45453291113 70832.4088457244 70655.28330884853 60046.33635022256 55657.23025804653 70250.32916829098 0.898079012723309 1.0915987843076294 1.00741050263465 0.908216899845193 0.9421799914182714 1.0082857928827493 1.0057644447414253 0.8547481137971065 0.7922700280124615 1.0 16.100217364859503 -7.764622413862009 24.999694560223556 0.8676317733323468 0.9823960910807171 0.2745317826695063 0.0716681936958027 94.71694412011459 743884.5105663142 0.03673661308925925 0.01881697280343314 1.7194026277748757e-08 7.764622413862009 0.11476431774837037 NS(ph)TSSIEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSTSSIEPR 9 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6 C9J840;O95819-6 MAP4K4 1 NS(0.54)T(0.029)S(0.379)S(0.052)IEPR 73.881 0.028399 8776800.0 13938.0 19260.0 24971.0 19118.0 25227.0 22188.0 20463.0 19282.0 17881.0 18310.0 True False 16297.428111951693 21172.005515094344 25566.403343044854 18046.88044139227 20283.950443534755 21024.422220258344 18524.596500709482 18775.867930967757 18142.47579747149 21629.458058119737 0.7534829614389533 0.9788504852134442 1.1820177497904152 0.8343658168826583 0.9377928188968251 0.9720272308147702 0.8564521797510001 0.8680692729570847 0.8387855002525489 1.0 14.400709897523496 -7.260573252530666 24.806130392093298 0.8798325107915742 0.9503926393070075 0.04428432919087544 0.11141480819059947 197.56293112351784 5658419.824885296 0.04501323049163435 0.03278473586844545 5.488159789070325e-08 7.260573252530666 0.07056012851543325 NS(ph)TSSIEPR ddPTM_PC-9_Lapatinib_30min_R1 1 NSTSSIEPR 9 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6 C9J840;O95819-6 MAP4K4 1 NS(0.874)T(0.008)S(0.077)S(0.041)IEPR 70.54 0.037396 6261000.0 15473.0 23604.0 18409.0 18622.0 21640.0 21228.0 23139.0 19352.0 22545.0 18265.0 True False 15252.352182599308 23549.346388225436 16895.483080794984 19991.524001170936 20367.177745876936 20320.12792488492 24337.024200003467 20251.16456794932 20005.74469062518 21422.08091341733 0.7119920909759181 1.0993024666187183 0.7886947654190217 0.9332204505235349 0.9507562700465914 0.9485599464876346 1.1360719016218643 0.9453406814118311 0.9338842837669867 1.0 14.386811007987374 -6.461247963828728 1.7444033055887815 0.9990548299603587 0.8893320173170497 0.1941559549991082 0.10711285838933012 0.6552582412881055 4.000128801613204 0.03903239081651036 0.04462413606932846 3.457419174107655e-07 6.461247963828728 -0.10972281264330896 NS(ph)TTIMSR ddPTM_PC-9_AZD4547_30min_R2 2 NSTTIMSR 8 0 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 NS(0.968)T(0.024)T(0.007)IMSR;NS(0.909)T(0.046)T(0.046)IMSR 97.81299999999999 0.0056979 41138500.0 131360.0 132117.0 156766.0 203309.0 180199.0 182554.0 144772.0 195980.0 156969.0 168893.0 True False 173129.74754226345 174821.23656125148 154687.18041091526 156439.25114273798 155181.47931115472 171138.8695213202 157656.42753947378 165695.79417238056 165266.06088143532 162980.1074770283 1.0622753305440402 1.072653830381675 0.9491169370637339 0.9598671492150522 0.9521498157867347 1.0500598641796934 0.9673354004978498 1.0166626880874712 1.0140259657438822 1.0 17.314336361619617 -5.245258744295097 24.70481698365574 0.9883474423412092 1.067464600494845 0.509650369023595 0.030921087840411022 585.1582455460792 893423.7251826163 0.008177307407572484 0.021484861868558264 5.685141201526689e-06 5.245258744295097 0.07911715815363574 NS(ph)TTIMSR ddPTM_PC-9_Lapatinib_30min_R1 3 NSTTIMSR 8 0 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 NS(0.897)T(0.08)T(0.024)IMSR;NS(0.878)T(0.081)T(0.041)IMSR;NS(0.92)T(0.04)T(0.04)IMSR 80.916 0.016398 45808000.0 152964.0 186430.0 179234.0 158418.0 193070.0 206528.0 201882.0 189557.0 207017.0 196479.0 True False 150782.70530983797 185998.3327892248 164498.0723832478 170068.58818695633 181714.00219022442 197695.27888028245 212334.46214378768 198364.5102318505 183700.56547434672 230440.1333581895 0.6543248483347547 0.8071438341867055 0.7138429837981249 0.7380163589933644 0.7885518878249104 0.8579029876405714 0.9214300436710003 0.8608071317313396 0.7971726226560018 1.0 17.814032472270007 -6.6388951969565415 2.118505460539717 0.8844466780972838 0.732601936976208 0.620567106351336 0.05925419361217313 0.22487757281564863 2.0627679537403885 0.021740959127611578 0.02170823662334017 2.2967028168036503e-07 6.6388951969565415 -0.15184474112107582 NS(ph)VNMPGMVTHIK ddPTM_PC-9_Lapatinib_30min_R1 1 NSVNMPGMVTHIK 13 0 E7EPJ7;O75962-4;O75962;O75962-5;O75962-2;E7EWP2;F5H228 E7EPJ7 TRIO Triple functional domain protein 1 NS(0.996)VNMPGMVT(0.004)HIK 56.086999999999996 0.038017 2139900.0 3397.5 5011.1 4935.7 3706.2 4917.5 3277.3 4666.8 6113.8 4581.1 4942.1 True False 3349.051026974808 4999.497105831068 4529.90579835297 3978.766311520767 4628.262318176978 3137.1375187594413 4908.424069172229 6397.869467524217 4065.1282768783744 5796.335400065689 0.5777876530293353 0.8625272281128539 0.7815120219409031 0.6864278957141915 0.7984807639193078 0.5412277417079572 0.8468150530275736 1.1037783402685273 0.7013273035981156 1.0 12.500925362305646 -7.516745787502767 24.903307002295193 0.9365910489999677 0.719203351820872 0.3828050654881101 0.13068216231319005 279.4323663648231 1134669.8285774966 0.05621836866146335 0.03387351694287525 3.0426655163290625e-08 7.516745787502767 -0.21738769717909567 NS(ph)WDSPAFSNDVIR ddPTM_PC-9_Lapatinib_30min_R1 1 NSWDSPAFSNDVIR 14 0 A0A0C4DGT3;A0A3B3IU98;Q6DN90-2;A0A2R8Y7T6;A0A3B3IRZ4;Q6DN90;Q6DN90-3;A0A2R8Y695 A0A0C4DGT3;A0A2R8Y7T6 IQSEC1 IQ motif and SEC7 domain-containing protein 1 1 NS(0.921)WDS(0.054)PAFS(0.025)NDVIR 151.31 0.00024221 15970000.0 19239.0 20959.0 22602.0 14780.0 17472.0 19824.0 16433.0 17835.0 18276.0 15930.0 True False 18964.648331999495 20910.470723217128 20743.750806243042 15866.970504634637 16444.33131127365 18976.173732001087 17283.820332713472 18663.679209868555 16217.564425188097 18683.479274609253 1.01504907374358 1.1191957566294595 1.1102723695812742 0.8492513771884963 0.8801535875398436 1.0156659502809846 0.9250857443989081 0.9989402367487512 0.868016293262234 1.0 14.189475521150666 -5.746685470282764 24.999944784619643 0.9346327081494102 1.0852747848141184 0.5562994132329 0.06038936832686516 174.1117303767915 295023.3865339689 0.016350217280637735 0.02816752357823928 1.7919031367980085e-06 5.746685470282764 0.1506420766647082 NSAECVS(ph)EDDTTESQNYFGSLRK ddPTM_PC-9_AZD4547_30min_R2 2 NSAECVSEDDTTESQNYFGSLRK 23 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 NS(0.003)AECVS(0.996)EDDT(0.001)TESQNYFGSLRK;NS(0.001)AECVS(0.993)EDDT(0.005)T(0.001)ESQNYFGSLRK 84.398 1.6632e-05 14724100.0 31525.8 21926.5 34592.0 57198.0 45745.0 37737.0 32400.0 40987.0 30809.1 42397.0 True False 41550.34862262406 29013.812328922668 34133.287477988706 44011.88480029078 39394.096366177204 35377.299424422665 35283.537232883165 34653.40093756175 32437.60612797576 40912.69393464243 1.0155857418971304 0.7091640647098895 0.8342957697314248 1.0757513272188644 0.9628819952337734 0.8647022726231985 0.8624105097857456 0.8470085346352447 0.7928494315186008 1.0 15.320260915508978 -10.185965915529334 14.091386389529918 0.9999999999999982 0.8838283357646988 0.10278910208728842 0.10191290438892112 0.0 0.0 0.10231406975476107 0.02481480685798195 6.51679537424146e-11 10.185965915529334 -0.11617166423529945 NSAECVS(ph)EDDTTESQNYFGSLRK ddPTM_PC-9_Lapatinib_30min_R1 1 NSAECVSEDDTTESQNYFGSLRK 23 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 NS(0.003)AECVS(0.814)EDDT(0.12)T(0.055)ES(0.003)QNY(0.003)FGS(0.001)LRK 43.604 0.032757999999999995 5858700.0 16750.0 18661.0 20917.0 21894.0 18316.0 26069.0 14115.0 17115.0 23774.0 14982.0 True False 16511.141928426194 18617.79160102842 19197.285001954962 23504.157796242973 17238.688890641486 24954.08963980712 14845.805634774582 17910.22538137933 21096.32176868144 17571.61873773985 0.9396483144130602 1.0595376486880876 1.0925165910140966 1.3376205201721898 0.9810529779829956 1.420136073531541 0.8448741038803192 1.019270088242481 1.2005906845321728 1.0 14.100959481387362 -10.13989631659279 10.390619573487912 1.0000163994113054 1.1011985003200748 0.03049593396309558 0.1680042338026833 0.0 0.0 0.15790992230036804 0.03829878170455855 7.246089324672337e-11 10.13989631659279 0.10118210090876945 NSAIS(ph)PQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSAISPQK 8 0 Q9H582-2;Q9H582 Q9H582-2 ZNF644 Zinc finger protein 644 1 NS(0.004)AIS(0.996)PQK 81.625 0.017619 12951000.0 198790.0 179550.0 224440.0 285880.0 341090.0 250310.0 256850.0 327990.0 215910.0 187840.0 True False 232441.22071853024 197374.53739538873 229791.50079343954 269863.0704354654 274255.86303505284 237183.3029544289 232519.3085670346 319380.6100341316 219067.2752884101 221893.9050593786 1.0475331472323641 0.8894995891958885 1.0355917650462168 1.2161806353502602 1.235977450402084 1.068904091308677 1.047885062479804 1.4393392641797245 0.9872613455957158 1.0 17.759510514836215 -5.577095934777953 5.2801203839341255 1.1566715203183957 0.9665260703041105 0.22014773338381932 0.13235849667751726 0.2397148596754796 14.136057177623282 0.03487897913575917 0.06254475850214226 2.647915154863836e-06 5.577095934777953 -0.19014545001428518 NSAIS(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 1 NSAISPQK 8 0 Q9H582-2;Q9H582 Q9H582-2 ZNF644 Zinc finger protein 644 1 NS(0.233)AIS(0.767)PQK 72.096 0.033615 24323000.0 173880.0 294040.0 350290.0 383380.0 355250.0 304960.0 265910.0 246400.0 309380.0 264790.0 True False 171400.43931431367 293359.1684457641 321490.50835850206 411575.04411818855 334354.8934483729 291917.5716964812 279677.5186923778 257848.64352742446 274534.36648417026 310558.5986895028 0.5519101388195026 0.944617761941492 1.0352007953253584 1.3252733811105395 1.0766241696713144 0.9399758143175454 0.900562791925784 0.8302737216599245 0.8840018200837206 1.0 18.24450598785004 -6.984752095040517 5.901131012745403 0.8932396962342307 1.0064983974324966 0.03742877729961269 0.18258843398781155 0.5072635202485328 62.63008603591208 0.07167840316993876 0.06111015941520304 1.0357332175511302e-07 6.984752095040517 0.11325870119826587 NSAS(ph)ATTPLSGNSSR ddPTM_PC-9_Lapatinib_30min_R1 1 NSASATTPLSGNSSR 15 0 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 NS(0.062)AS(0.634)AT(0.152)T(0.152)PLSGNSSR 127.2 2.1455e-05 2620500.0 14752.0 16456.0 15707.0 12746.0 16229.0 15599.0 15141.0 14590.0 19738.0 14461.0 True False 14541.63377481453 16417.897143053626 14415.631090773362 13683.383359409561 15274.442127441633 14931.867133045038 15924.926894518012 15267.904663413632 17514.89858964559 16960.564581928706 0.8573791104989795 0.9680041642332304 0.8499499542682122 0.8067764073130593 0.9005857118527989 0.8803873869242995 0.9389384897885915 0.9002002610031872 1.032683700182217 1.0 14.049896574567999 -8.023171875085112 1.28227376778271 1.0163148040132581 0.8790613388165762 0.5549826365194683 0.044910500291587926 0.3514844417116148 1.0448086927404547 0.04152778364598723 0.014103973619636384 9.480431943093021e-09 8.023171875085112 -0.1372534651966819 NSASAT(ph)TPLSGNSSR ddPTM_PC-9_Lapatinib_30min_R1 1 NSASATTPLSGNSSR 15 0 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 NSAS(0.016)AT(0.492)T(0.492)PLSGNSSR 119.04 0.00025276 2044200.0 14837.0 14125.0 14329.0 13214.0 15092.0 17686.0 15109.0 14778.0 16440.0 12952.0 True False 14625.421659227439 14092.294430337413 13150.92493153954 14185.801640611793 14204.318232013618 16929.61100807966 15891.270091095223 15464.63982974138 14588.354079125207 15190.735942544832 0.9627855894898343 0.9276900397477779 0.865720066577395 0.9338455815614232 0.9350645212804638 1.1144694419093117 1.046115879520254 1.01803098205594 0.9603454456915067 1.0 13.89090414504056 -6.611716566563301 9.271941630701651 1.0299587805061765 0.920772135627462 0.5913249851917062 0.04278806339519081 0.214846361612927 20.394983901933653 0.014757159297748557 0.01475065546640232 2.445025728286144e-07 6.611716566563301 -0.10918664487871454 NSASATT(ph)PLSGNSSR ddPTM_PC-9_AZD4547_30min_R2 4 NSASATTPLSGNSSR 15 0 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 NSASAT(0.023)T(0.636)PLS(0.341)GNSSR;NS(0.001)AS(0.01)AT(0.233)T(0.71)PLS(0.047)GNSSR;NSASAT(0.094)T(0.895)PLS(0.009)GNS(0.002)S(0.001)R;NSASAT(0.009)T(0.785)PLS(0.206)GNSSR 181.69 5.373799999999999e-29 55650300.0 62640.8 64778.2 74804.3 112317.0 93443.0 90670.0 75119.1 100725.0 75422.7 78120.0 True False 82559.27139041894 85716.48634325669 73812.34610573872 86424.05093035175 80470.05239358818 85000.3905666164 81804.55437502098 85160.26568023798 79409.3899435061 75385.04257787723 1.0951678020892581 1.1370489875986534 0.97913781808223 1.1464349952587818 1.0674538295903704 1.1275498117389262 1.0851563065778203 1.129670592044335 1.0533838972296325 1.0 16.201990681035916 -8.54018659066457 6.334402132403116 1.0000101130266712 1.0947517541228153 0.3023880066975638 0.04578401905823428 0.18613563003057934 45.488628824863355 0.041608115658633364 0.010776636716973131 2.8827926714312076e-09 8.54018659066457 0.09474164109614414 NSASATT(ph)PLSGNSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSASATTPLSGNSSR 15 0 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 NS(0.006)AS(0.08)AT(0.287)T(0.618)PLS(0.007)GNS(0.001)S(0.001)R;NSASAT(0.043)T(0.492)PLS(0.201)GNS(0.132)S(0.132)R 88.19 0.012046 42154200.0 27900.0 31445.0 34288.0 39573.0 38040.0 33840.0 40581.0 35632.0 28654.0 28099.0 True False 32622.91894988178 34566.651787234776 35105.555957964134 37355.85310739702 30586.335072424845 32065.370828084648 36736.873899002654 34696.697755224704 29073.010541957818 33193.12626843839 0.9828215241328807 1.0413798178480826 1.057615232565309 1.1254093032784547 0.9214659331895408 0.966024428333945 1.106761490373199 1.0452976762305146 0.875874429749084 1.0 15.018596894460348 -6.262740596395816 24.998996495454776 0.9932177765001488 1.051476616974395 0.18127226576764344 0.0675477257092149 250.80088639181383 4818427.431703366 0.021549011300475422 0.025793588226004343 5.460839390194148e-07 6.262740596395816 0.05825884047424623 NSASATTPLS(ph)GNSSR ddPTM_PC-9_AZD4547_30min_R2 1 NSASATTPLSGNSSR 15 0 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 NSASATT(0.002)PLS(0.998)GNSSR 158.45 2.3054e-14 0.0 18194.0 23662.0 29519.0 43600.0 29478.0 25818.0 32254.0 38493.0 28988.0 30485.0 True False 23979.313541290692 31310.27876437042 29127.558772628046 33548.69361328505 25385.48852731822 24203.59637861369 35124.543515722646 32544.791331143155 30520.24649982508 29417.729428911858 0.8151313512906176 1.0643336305078175 0.9901361980711322 1.1404243041379416 0.8629316068958491 0.8227554215936972 1.193992337192486 1.1062985472685056 1.0374779798548852 1.0 14.844398277805597 -7.271629682256477 24.998128012180473 1.0933004191817202 0.9611346915816324 0.26920656961269784 0.10764500157297685 1060.915939213288 2602553.3660812527 0.046055865782453416 0.0314489021469712 5.35020370463396e-08 7.271629682256477 -0.1321657276000877 NSASATTPLS(ph)GNSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSASATTPLSGNSSR 15 0 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 NSASATT(0.001)PLS(0.999)GNSSR;NSASAT(0.074)T(0.254)PLS(0.645)GNS(0.023)S(0.004)R 202.79 3.3268e-11 58546000.0 68503.0 68542.0 67784.0 78929.0 83891.0 66131.0 66403.0 65965.0 55386.0 47251.0 True False 80099.20490407725 75346.3967817029 69400.22763225166 74506.8640212707 67453.16076658231 62662.97394302792 60112.82712391201 64233.488645694764 56195.91546998241 55817.23226128982 1.435026454359461 1.3498769775791424 1.2433477050129889 1.3348362325185092 1.208464806187859 1.1226456670171685 1.0769582204025057 1.1507824025563833 1.0067843422783829 1.0 15.768422968627238 -5.689059572745062 0.31234277509765007 0.9847859425480779 1.592772207245001 0.8950584002013497 0.04560657293660849 1.3058908033699794 0.160258186157779 0.055071824040867454 0.28973161465546327 2.046163942475374e-06 5.689059572745062 0.6079862646969231 NSASATTPLS(ph)GNSSR ddPTM_PC-9_Lapatinib_30min_R1 3 NSASATTPLSGNSSR 15 0 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 NSASAT(0.082)T(0.132)PLS(0.786)GNSSR;NSASAT(0.004)T(0.008)PLS(0.951)GNS(0.021)S(0.017)R;NSAS(0.002)AT(0.024)T(0.361)PLS(0.602)GNS(0.009)S(0.002)R 176.44 2.0116e-28 93806000.0 115096.0 98867.0 107727.0 86958.0 100936.0 88787.0 78950.0 89786.0 89029.0 62412.0 True False 113454.70993397868 98638.07953587016 98870.1018982454 93353.18140338412 94999.1429278112 84989.78698260587 83037.64469468311 93957.7853399077 79001.61650306801 73199.83104123747 1.54993130885867 1.3475178580713107 1.3506875697916088 1.2753196295056086 1.297805494582262 1.1610653436443927 1.1343966715975542 1.2835792651895075 1.0792595471779447 1.0 16.15955269805535 -1.5228787452804973 0.1642772401727729 0.9919715532777729 2.978776069011261 0.8306796910305619 0.061934316118689145 25.0741075314191 0.2647687906418512 0.1731661690703927 12.131305419520395 0.02999999999998897 1.5228787452804973 1.9868045157334882 NSASATTPLSGNS(ph)SR ddPTM_PC-9_AZD4547_30min_R2 1 NSASATTPLSGNSSR 15 0 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 NSASAT(0.012)T(0.007)PLS(0.182)GNS(0.514)S(0.285)R 85.146 0.0058831000000000005 41663000.0 16910.0 15735.0 19787.0 29399.0 22936.0 21941.0 19403.0 24373.0 17471.0 21285.0 True False 22287.028250149808 20821.031035304226 19524.611451403867 22621.514760022204 19751.73230417839 20569.025801501382 21129.829411408387 20606.712885822155 18394.4813922466 20539.81862864978 1.0850645106993764 1.0136910851910932 0.9505737029328067 1.1013492947045205 0.9616312909709857 1.0014219781284175 1.0287252187288372 1.0032568085620321 0.8955522794436569 1.0 14.326135821930835 -8.06516426608437 9.069746560899835 0.9479382281377327 1.0174385226504508 0.24510074375574742 0.050052826275413735 0.6200295439293512 81.93876639818151 0.03218974702909362 0.012160893983277183 8.606681543835537e-09 8.06516426608437 0.06950029451271811 NSASATTPLSGNS(ph)SR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSASATTPLSGNSSR 15 0 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 NSASAT(0.004)T(0.225)PLS(0.082)GNS(0.344)S(0.344)R 68.171 0.028336 5908400.0 14258.0 20327.0 21036.0 21806.0 19461.0 17468.0 21713.0 13214.0 18884.0 14923.0 True False 16671.597791663593 22344.930223537012 21537.578019474266 20584.280516005867 15647.756751957417 16551.947329343468 19656.187451493195 12867.146501390313 19160.14277498191 17628.42176959699 0.9457226522919033 1.2675513733211439 1.2217530474917067 1.1676757446039059 0.8876436561635062 0.9389352912970308 1.1150282032276655 0.7299091586055507 1.0868892873908098 1.0 14.105615698955377 -6.250746122514007 24.462507230469 0.9529544730584102 1.16410094181076 0.34759737391890255 0.12742000763935565 553.119299623403 1265345.532508151 0.0363303600583206 0.04639744639007572 5.613760462621846e-07 6.250746122514007 0.21114646875234977 NSASATTPLSGNS(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 2 NSASATTPLSGNSSR 15 0 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 NSASAT(0.005)T(0.037)PLS(0.11)GNS(0.526)S(0.322)R;NSASATTPLS(0.002)GNS(0.635)S(0.363)R 109.13 0.00066294 72453000.0 71705.0 61062.0 67381.0 63474.0 69071.0 59913.0 55967.0 57012.0 61641.0 47265.0 True False 70682.4735509136 60920.61469063808 61841.19427818171 68142.08970305679 65008.379578810745 57350.660654024425 58864.6974113658 59660.98565253861 54698.341471493724 55434.69227334625 1.2750584634326307 1.0989618989899135 1.115568459787695 1.2292318565971445 1.1727020916478985 1.0345626231896556 1.0618747033194724 1.0762391420584185 0.9867167874185788 1.0 15.75850150936405 -6.760274688082763 24.884000944724644 1.038518334962538 1.1732406038388332 0.6514141895212819 0.05338228116530176 20.47866787982883 437535.70302205114 0.018180867131353088 0.01722315207526923 1.7367020299656384e-07 6.760274688082763 0.13472226887629524 NSASATTPLSGNSS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 NSASATTPLSGNSSR 15 0 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 NSASATT(0.002)PLS(0.243)GNS(0.182)S(0.573)R;NSAS(0.001)AT(0.025)T(0.043)PLS(0.077)GNS(0.225)S(0.628)R 142.84 9.4406e-05 75666000.0 86279.0 78932.0 99247.0 146012.0 125132.0 107634.0 101222.0 109804.0 96457.0 98771.0 True False 113713.92728531468 104445.22540061217 97930.91993316208 112351.18926291246 107759.58173554429 100903.6289648966 110230.56190700324 92836.31484490295 101555.52009913162 95313.05735355278 1.1930571785511612 1.0958123503811725 1.0274659385848743 1.1787596829063902 1.1305857217004651 1.0586548345690585 1.1565106079654512 0.9740146567803125 1.0654943081137682 1.0 16.54038624834179 -7.761368356660478 24.999999999940208 1.0148158565307082 1.115916058268146 0.4628655858580282 0.052651867402306075 1.7877062730431204 630005.2025952376 0.026297211517671053 0.013915929384715177 1.732334056257076e-08 7.761368356660478 0.10110020173743783 NSASATTPLSGNSS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NSASATTPLSGNSSR 15 0 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 NSASATTPLS(0.016)GNS(0.242)S(0.742)R;NSASATT(0.001)PLS(0.012)GNS(0.258)S(0.728)R;NSASAT(0.01)T(0.009)PLS(0.019)GNS(0.46)S(0.501)R 127.01 2.1999e-05 86759000.0 108368.0 112275.0 105417.0 124377.0 123636.0 107808.0 124135.0 106260.0 106804.0 83938.0 True False 126712.56203443717 123420.920000375 107930.54107619889 117408.55992567481 99410.41332845225 102154.35869486263 112376.03414042758 103470.78759177639 108365.80644668337 99155.2949471574 1.277920277499712 1.2447234418106408 1.0885000254773893 1.1840876474447994 1.0025729173760294 1.0302461280489712 1.1333336681648305 1.0435225637412389 1.0928897594872218 1.0 16.597402194767454 -5.104020190614357 0.9257737872202038 1.0592971097119939 1.3509553904469218 0.6856636256057288 0.05246147710589745 0.7992361538341172 0.7572389757841048 0.018613486431948937 0.2118898746286505 7.87009200308635e-06 5.104020190614357 0.29165828073492794 NSASATTPLSGNSS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 NSASATTPLSGNSSR 15 0 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 NSASATTPLS(0.001)GNS(0.337)S(0.661)R 141.74 8.3669e-05 30820000.0 61365.0 54161.0 46914.0 49408.0 54931.0 46547.0 36087.0 41107.0 44937.0 36359.0 True False 60489.92384703723 54035.59353214195 43056.91201327697 53041.62914025631 51700.066578501195 44556.293316356634 37955.40828495289 43016.98128848143 39875.72185241178 42643.60470467784 1.4184993099422882 1.2671441334839701 1.0096921287837046 1.243835494386286 1.2123756173180618 1.04485288298034 0.8900609727486131 1.008755746292776 0.9350926622776231 1.0 15.380041775192392 -6.868274188077755 3.259861178057602 0.9593145416967155 1.2225577365422495 0.6348784234596355 0.09806693192471172 0.17675301860449977 3.718888011465586 0.03851076365292032 0.0338267572063718 1.3543340952235417e-07 6.868274188077755 0.26324319484553405 NSATCHSEDS(ph)DLEID ddPTM_PC-9_AZD4547_30min_R2 1 NSATCHSEDSDLEID 15 0 Q13371-2;Q13371 Q13371-2 PDCL Phosducin-like protein 1 NSATCHS(0.008)EDS(0.992)DLEID 91.355 0.0039315 17936000.0 16341.0 12232.0 32094.0 48670.0 45703.0 36703.0 22157.0 42083.0 28246.0 29208.0 True False 21537.098086085047 16185.754790202822 31668.412590152944 37449.88344400423 39357.92734120443 34407.955607880496 24128.930076203476 35580.039321136224 29739.025894648115 28185.436810223302 0.7641214940572857 0.5742594978812602 1.123573595945347 1.3286962233780448 1.3963923144497334 1.2207707065018836 0.8560779184891516 1.2623554341450114 1.0551202770028139 1.0 14.78266230569665 -5.30552896382053 6.573539564428234 1.172735954020509 0.6694295105926099 0.6021858251256236 0.15766301637747712 0.1288905030133266 15.145010342781486 0.04315367503824487 0.09267141882453228 4.948471076440346e-06 5.30552896382053 -0.503306443427899 NSATCHSEDS(ph)DLEID ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSATCHSEDSDLEID 15 0 Q13371-2;Q13371 Q13371-2 PDCL Phosducin-like protein 1 NSATCHS(0.018)EDS(0.981)DLEID 89.911 0.02041 0.0 16085.0 19338.0 23460.0 27168.0 35932.0 29080.0 26488.0 24296.0 23388.0 17543.0 True False 18807.872806768763 21257.74883961029 24019.37537254545 25645.865039844404 28891.38254002025 27554.99360758574 23978.86488348693 23658.255743739883 23730.005254251068 20723.407029688402 0.9075666361146388 1.025784457601802 1.1590456790302501 1.2375313095527236 1.3941425026604162 1.329655571022197 1.1570908610314294 1.141619990856089 1.14508223576632 1.0 14.338973588209214 -5.127803433660404 1.975266121471312 1.2173503046308733 0.9025283859295551 0.45505728783651944 0.1034728919862326 0.37805058738980646 2.4630600136594967 0.03055797708459276 0.16658051957813202 7.450691238764826e-06 5.127803433660404 -0.31482191870131826 NSATS(ph)ADEQPHIGNYR ddPTM_PC-9_AZD4547_30min_R2 1 NSATSADEQPHIGNYR 16 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;F5H4J8;F5H6N2;F5H4F6;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 NS(0.034)AT(0.197)S(0.768)ADEQPHIGNYR 91.414 0.007063 0.0 2806.9 3893.8 8294.5 9205.4 8308.0 6590.0 8475.0 7973.1 6618.5 3699.7 True False 3699.435812853077 5152.394702590888 8184.509510469973 7083.237252012256 7154.577606518745 6177.926258233181 9229.258581749535 6741.040598611115 6968.340398064452 3570.1746291010377 1.0362058434616648 1.4431772218067245 2.2924675571208164 1.984003021666142 2.003985336795767 1.7304269118591462 2.5851000414714846 1.8881543058605215 1.951820603189672 1.0 11.801778927649357 -5.033975610818579 4.177709988029631 1.9806985968883082 1.0956785431604756 0.350536503998939 0.3881712924302854 0.18491099638769123 7.203800093864078 0.09283789046597304 0.32733261706392724 9.247501047495336e-06 5.033975610818579 -0.8850200537278325 NSDDAPWS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 NSDDAPWSPK 10 0 Q9UPP1-4;Q9UPP1-3;Q9UPP1-2;Q9UPP1;H0Y3N9;Q9UPP1-5;H0Y589 Q9UPP1-4 PHF8 Histone lysine demethylase PHF8 1 NSDDAPWS(1)PK;NSDDAPWS(1)PK 116.79 0.0010114 79357000.0 938970.0 911230.0 677490.0 741230.0 796780.0 755610.0 709550.0 734800.0 670170.0 654310.0 True False 925580.1156139929 909120.1029208048 621789.387387029 795742.5268707953 749914.966929751 723294.3217129398 746287.0271451857 768941.4905192817 594688.397397041 767406.6116867291 1.2061143356318038 1.18466545515238 0.8102476287249607 1.036924252088192 0.9772068099354367 0.9425177092534657 0.9724792773219357 1.0020000854946753 0.7749325954984145 1.0 19.54963166914891 -5.198838669747263 9.582835362835153 0.9457779874307386 1.1965111346555577 0.6203968143161409 0.07993684506880364 0.3272052093997472 48.23563514646566 0.019378802205827526 0.0514436039418489 6.326468212429088e-06 5.198838669747263 0.2507331472248191 NSDGGS(ph)DPETQK ddPTM_PC-9_AZD4547_30min_R2 1 NSDGGSDPETQK 12 0 O75554-2;O75554 O75554-2 WBP4 WW domain-binding protein 4 1 NS(0.021)DGGS(0.979)DPETQK 93.478 0.018417 0.0 22713.0 25431.0 25340.0 27009.0 23692.0 26175.0 32767.0 23118.0 30371.0 30131.0 True False 29935.26154025148 33651.07341968998 25003.975043138118 20782.492334890285 20402.774753688263 24538.273112178053 35683.19952190998 19545.644298791147 31976.34905637463 29076.12286116264 1.0295479106066237 1.1573438996792162 0.8599487339674251 0.7147614705759046 0.7017020409189603 0.8439320892041678 1.2272337578258241 0.6722231981244832 1.0997459740096869 1.0 14.82754728629355 -5.269576457731576 24.013938343313875 0.8756605013583973 1.093445908658329 0.1790958147778242 0.1721146766676333 500.7105789771877 1477691.701309939 0.045149358858891604 0.096790421912742 5.375557878621299e-06 5.269576457731576 0.21778540729993168 NSDGGS(ph)DPETQK ddPTM_PC-9_Lapatinib_30min_R1 3 NSDGGSDPETQK 12 0 O75554-2;O75554 O75554-2 WBP4 WW domain-binding protein 4 1 NS(0.023)DGGS(0.976)DPET(0.001)QK;NSDGGS(1)DPETQK;NSDGGS(0.999)DPET(0.001)QK 138.28 0.00014599 0.0 28873.0 74348.0 56836.0 56113.0 94894.0 67018.0 87556.0 97981.0 69132.0 66701.0 True False 28461.265725340294 74175.85177392732 52163.163473304565 60239.737207480655 89312.52148878224 64151.79636658846 92089.22126520179 102533.55495722624 61345.626167766655 78230.17897650436 0.3638144012669119 0.948174384161965 0.6667907980751423 0.7700319492503404 1.1416632641938138 0.8200389824731936 1.1771572361206006 1.3106649671352681 0.7841682963066107 1.0 16.255437645145975 -4.551525453253026 0.48593234837620647 1.0773319896944977 3.392543559119211e-14 0.459582578615954 0.19376481605420137 5.335694636993009 0.8239521298144565 0.12336534723467628 3.452972286651145 2.8085007665422455e-05 4.551525453253026 -1.0773319896944638 NSDGGS(ph)DPETQKEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSDGGSDPETQKEK 14 1 O75554-2;O75554 O75554-2 WBP4 WW domain-binding protein 4 1 NS(0.015)DGGS(0.717)DPET(0.267)QKEK;NS(0.036)DGGS(0.96)DPET(0.004)QKEK 61.732 0.024031999999999998 20428700.0 74427.0 73597.0 62292.0 84152.0 91977.0 72959.0 80603.0 81514.0 68700.0 63824.0 True False 87026.02109974397 80903.22377437179 63777.27752372556 79437.23626446488 73954.767112419 69132.90160302102 72967.70032481491 79374.34387122204 69704.60753236905 75394.78596949398 1.1542710809598449 1.073061256611387 0.8459109831485023 1.0536171068461755 0.980900285894337 0.9169453923643124 0.9678083091095834 1.0527829325404312 0.9245282234844823 1.0 16.20217713492596 -5.020220199124856 10.974044663291675 0.9705979198501673 1.134160976490425 0.5089103221158577 0.05964681458242789 0.4300651826729681 235.84782978897547 0.014548527416410825 0.04174631097491927 9.545085015155295e-06 5.020220199124856 0.16356305664025772 NSDGGS(ph)DPETQKEK ddPTM_PC-9_Lapatinib_30min_R1 1 NSDGGSDPETQKEK 14 1 O75554-2;O75554 O75554-2 WBP4 WW domain-binding protein 4 1 NS(0.001)DGGS(0.993)DPET(0.006)QKEK 84.605 0.034852 5060600.0 10934.0 16201.0 19430.0 16287.0 17756.0 17879.0 16069.0 17586.0 15612.0 17730.0 True False 10778.079154949972 16163.487579886481 17832.54040196896 17484.800311839266 16711.62698963914 17114.356847984618 16900.97419377915 18403.109760849373 13853.612158351754 20794.60687626002 0.5183112726817005 0.7772922891049884 0.8575560244097388 0.8408334149274366 0.8036519800101545 0.8230190140080539 0.8127575719199578 0.8849943579293688 0.6662117846607434 1.0 14.343921790524044 -4.765344380141929 3.334054254656594 0.8294583384658577 0.4701701576305836 0.5965032542503452 0.07796585616245597 0.2179974038217527 3.727476808486098 0.018075774169738653 0.20776989734104123 1.7165466866144495e-05 4.765344380141929 -0.3592881808352741 NSDLLT(ph)SPDVGLLK ddPTM_PC-9_AZD4547_30min_R2 4 NSDLLTSPDVGLLK 14 0 P05412 P05412 JUN Transcription factor AP-1 1 NSDLLT(0.925)S(0.075)PDVGLLK;NSDLLT(0.62)S(0.38)PDVGLLK;NS(0.004)DLLT(0.974)S(0.021)PDVGLLK;NS(0.001)DLLT(0.629)S(0.37)PDVGLLK 177.07 4.7943999999999994e-05 44094600.0 136353.0 131403.9 154726.0 279012.0 275375.0 276709.0 217636.0 246550.0 242662.0 260510.0 True False 179710.4176814121 173877.6409316818 152674.23214382757 214690.09409242854 237143.9345684999 259406.3424870179 237005.18238320283 208451.36265537492 255488.6179157086 251389.62419307322 0.7148680788169293 0.6916659408271346 0.6073211360011029 0.8540133459427961 0.9433322291232183 1.03188961485454 0.942780288343075 0.829196365301375 1.0163053417013235 1.0 17.939565579906805 -5.94893417237772 3.7489246768379885 0.9522020526595775 0.6742800078513713 0.823707409884403 0.059602137424583694 0.09354833156632861 2.737165603375863 0.01807088319641795 0.02722083175081073 1.1247754474251798e-06 5.94893417237772 -0.27792204480820615 NSDLLT(ph)SPDVGLLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 NSDLLTSPDVGLLK 14 0 P05412 P05412 JUN Transcription factor AP-1 1 NS(0.006)DLLT(0.667)S(0.327)PDVGLLK;NS(0.004)DLLT(0.789)S(0.207)PDVGLLK;NSDLLT(0.959)S(0.041)PDVGLLK;NSDLLT(0.837)S(0.163)PDVGLLK;NS(0.012)DLLT(0.671)S(0.317)PDVGLLK 193.54 3.9641e-07 30856700.0 147050.6 138006.0 124839.3 215698.0 257993.0 269572.0 341572.0 282974.0 292940.0 249054.0 True False 171943.36219826082 151706.32363011976 127815.94236768191 203613.1403623515 207441.1236682463 255435.16976561595 309215.8273928724 275546.23233573657 297223.6933119682 294205.5186896205 0.5844328242518686 0.5156474436843116 0.43444440789883537 0.6920779095825129 0.7050891655336062 0.8682201846631358 1.0510198067327468 0.9365773747651247 1.010258728781807 1.0 18.166464783271138 -6.57374306295501 1.1895074587989976 1.0022176986363376 0.5172967058815641 0.918933860157516 0.060267405333028524 0.11864283500561242 0.35385682560152626 0.028357319133232275 0.030614903800596262 2.668436896680509e-07 6.57374306295501 -0.4849209927547735 NSDLLT(ph)SPDVGLLK ddPTM_PC-9_Lapatinib_30min_R1 3 NSDLLTSPDVGLLK 14 0 P05412 P05412 JUN Transcription factor AP-1 1 NSDLLT(0.992)S(0.008)PDVGLLK;NS(0.059)DLLT(0.888)S(0.053)PDVGLLK;NS(0.001)DLLT(0.985)S(0.014)PDVGLLK 219.85 2.3131999999999998e-15 36369870.0 166704.7 148044.3 151097.5 137669.3 275696.0 281405.0 279691.0 250013.0 268869.0 256933.0 True False 164327.46040810188 147701.51251916433 138674.8468032169 147793.959573322 259480.10331919085 269369.96413709485 294172.03144142625 261629.51669732935 238586.14190391244 301343.5267082975 0.5453160457870792 0.4901433063207638 0.4601885705593904 0.4904500892643615 0.8610774094058085 0.8938966337838302 0.9762015950858195 0.8682101771198438 0.7917413873464931 1.0 18.201049548400754 -6.284287740249352 4.787361110494609 0.8988206771440792 0.49134797166334826 0.9218179936026054 0.05741881263818444 0.05056892161802113 3.17208336664575 0.01819722552265634 0.02162152095902295 5.196515891589486e-07 6.284287740249352 -0.40747270548073095 NSEPEEVIPSR ddPTM_PC-9_Lapatinib_30min_R1 1 NSEPEEVIPSR 11 0 P54577 P54577 YARS Tyrosine--tRNA ligase, cytoplasmic;Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed 0 94.363 0.025807999999999998 0.0 7321.7 7871.5 9837.6 5826.8 7985.6 8230.3 6753.5 8731.9 9890.9 4860.8 False True 7217.291215364667 7853.274025373514 9028.790502234173 6255.322309634992 7515.902708293659 7878.309254766363 7103.163184870715 9137.615951368169 8776.882686205567 5700.982803391125 1.2659731601140058 1.3775298569050476 1.583725265205775 1.0972357794017775 1.3183521100647702 1.3819212452421528 1.2459541503344875 1.6028141579260378 1.5395385302661848 1.0 12.476994934352714 -7.706746139814233 24.999994111908876 1.4283945484775356 1.3296477929609098 0.0 0.19002107328724185 287.16970973783725 131262.89077549992 0.08659814176185451 0.04999739001842346 1.964508264492727e-08 7.706746139814233 -0.0987467555166257 NSESESNKVAAETQS(ph)PSLFGSTK ddPTM_PC-9_AZD4547_30min_R2 4 NSESESNKVAAETQSPSLFGSTK 23 1 Q9UKX7-2;Q9UKX7 Q9UKX7-2 NUP50 Nuclear pore complex protein Nup50 1 NSESESNKVAAET(0.003)QS(0.677)PS(0.32)LFGS(0.001)TK;NSESESNKVAAET(0.209)QS(0.676)PS(0.114)LFGS(0.001)TK;NSESESNKVAAET(0.205)QS(0.721)PS(0.073)LFGS(0.001)TK;NSESESNKVAAET(0.142)QS(0.808)PS(0.049)LFGSTK 108.5 7.2211e-07 67135000.0 268335.0 178344.0 256887.0 497002.0 323981.0 254791.0 179466.0 223045.0 185565.0 238424.0 True False 353659.9482852714 235990.2102929964 253480.51053301612 382425.86750435596 279001.83046913246 238858.87849187967 195438.12632829044 188578.52031420855 195373.58706154433 230076.84833061733 1.5371383555161833 1.0257016818740565 1.1017210656883132 1.6621657949469786 1.212646263600632 1.038169986354484 0.8494471640512412 0.8196327517631142 0.8491666522691371 1.0 17.81175629294431 -6.883278546051036 2.589789379910385 0.8684514844368938 1.3052985228729717 0.5609617124013531 0.1805554211407141 0.22243902033461688 3.0294780372659385 0.07314446804502824 0.06298974810947545 1.3083425143712668e-07 6.883278546051036 0.43684703843607786 NSESESNKVAAETQS(ph)PSLFGSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSESESNKVAAETQSPSLFGSTK 23 1 Q9UKX7-2;Q9UKX7 Q9UKX7-2 NUP50 Nuclear pore complex protein Nup50 1 NSESESNKVAAET(0.016)QS(0.754)PS(0.227)LFGS(0.002)T(0.001)K;NS(0.002)ES(0.002)ES(0.002)NKVAAET(0.171)QS(0.72)PS(0.09)LFGS(0.01)T(0.004)K 84.87799999999999 1.6509e-05 18640800.0 52135.0 23125.6 26913.9 53707.0 57852.0 87707.0 78373.0 102485.0 95120.0 64395.0 True False 60960.42578681316 25421.35673623393 27555.629447534156 50697.9709104433 46516.31589405686 83107.49052065083 70948.94206861685 99794.87734183336 96510.95005063966 76069.3037494605 0.8013800939678708 0.3341867939262455 0.3622437447079906 0.6664708155791799 0.6114991672233725 1.092523349423193 0.9326882010421981 1.3118941862609217 1.2687239831786175 1.0 16.21502677989514 -6.764131063631026 1.3529247087711145 1.1810180633665028 0.49420049916581665 0.7377090145003756 0.16770868577561485 0.20298878517560268 0.7776393522635703 0.07846863466981345 0.07068870659137196 1.7213490189984702e-07 6.764131063631026 -0.6868175642006862 NSESESNKVAAETQS(ph)PSLFGSTK ddPTM_PC-9_Lapatinib_30min_R1 2 NSESESNKVAAETQSPSLFGSTK 23 1 Q9UKX7-2;Q9UKX7 Q9UKX7-2 NUP50 Nuclear pore complex protein Nup50 1 NSES(0.003)ES(0.002)NKVAAET(0.042)QS(0.756)PS(0.195)LFGS(0.001)T(0.001)K;NSESESNKVAAET(0.014)QS(0.809)PS(0.176)LFGS(0.001)TK 95.212 4.6081e-06 29053000.0 145616.0 65779.0 89616.0 75798.0 87626.0 130534.0 98609.0 97450.0 157390.0 100362.0 True False 143539.48913729584 65626.69276694968 82248.11840776361 81372.4377747158 82472.0109593444 124951.3651096159 103714.49152245742 101977.88275871534 139663.08080982463 117709.43797604095 1.2194390832663091 0.5575312727285946 0.698738519374332 0.6912991785015461 0.7006405975375661 1.0615237593356703 0.8811059954560982 0.8663526435278055 1.1865070737849603 1.0 16.844870475147438 -6.757506577380845 24.999713035865845 0.9833704493812512 0.7528063661561657 0.26863032815526344 0.18360457723217585 136.6122649045486 868405.2815029252 0.060326734859573614 0.058189929956713654 1.7478067917204667e-07 6.757506577380845 -0.23056408322508548 NSESESNKVAAETQSPS(ph)LFGSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSESESNKVAAETQSPSLFGSTK 23 1 Q9UKX7-2;Q9UKX7 Q9UKX7-2 NUP50 Nuclear pore complex protein Nup50 1 NSESESNKVAAET(0.005)QS(0.132)PS(0.783)LFGS(0.063)T(0.017)K 63.323 0.0012489 10518000.0 16762.0 6179.6 10614.0 16563.0 25026.0 33827.0 24672.0 38507.0 33530.0 16256.0 True False 19599.475535409263 6793.069848446365 10867.07801381915 15635.028807970504 20122.334950644163 32053.052570969845 22334.889550188374 37496.232051539024 34020.31281747212 19203.0841175748 1.0206420705865515 0.35374889819022864 0.5659027449592601 0.8141936322437506 1.0478699581505275 1.6691617020848575 1.1630886691657683 1.9526151019263727 1.771606717398925 1.0 14.229050413610963 -6.471450945336858 1.8106120915220998 1.5619698439658223 0.627043719121318 0.6079347325524677 0.30903642744628446 0.2187325265318855 1.4376172706527597 0.11331716747576882 0.1281377665501746 3.3771399213967605e-07 6.471450945336858 -0.9349261248445043 NSESESNKVAAETQSPS(ph)LFGSTK ddPTM_PC-9_Lapatinib_30min_R1 1 NSESESNKVAAETQSPSLFGSTK 23 1 Q9UKX7-2;Q9UKX7 Q9UKX7-2 NUP50 Nuclear pore complex protein Nup50 1 NSESESNKVAAET(0.035)QS(0.152)PS(0.813)LFGS(0.001)TK 93.596 5.4497000000000005e-06 9317400.0 44730.0 19177.0 26087.0 19046.0 25846.0 43842.0 35951.0 28104.0 47257.0 31886.0 True False 44092.141997522616 19132.596834731357 23942.22755873207 20446.706375593472 24325.789095191092 41966.97986069369 37812.366870406 29409.814438696158 41934.419021728725 37397.45261457568 1.179014582943483 0.5116016064493766 0.6402101181993495 0.5467406185742275 0.6504664728343047 1.1221881953621897 1.0110947197421838 0.7864122388708813 1.121317525391683 1.0 15.190652381601302 -6.750507347751434 24.99849115447805 0.9950340644315158 0.6823695286745278 0.37665659901825577 0.19311391945589487 226.4986210998577 517937.9911798142 0.0631373652944473 0.0625509170450322 1.7762032167665293e-07 6.750507347751434 -0.31266453575698794 NSGEPLPPKPGPGS(ph)PSHPGALDLDGVSR ddPTM_PC-9_AZD4547_30min_R2 2 NSGEPLPPKPGPGSPSHPGALDLDGVSR 28 1 A1X283;G3V144;A0A1B0GUF2 A1X283 SH3PXD2B SH3 and PX domain-containing protein 2B 1 NSGEPLPPKPGPGS(0.97)PS(0.03)HPGALDLDGVSR;NSGEPLPPKPGPGS(0.967)PS(0.033)HPGALDLDGVSR 80.191 5.4202e-06 23224000.0 56182.0 52653.0 67986.0 92519.0 79762.0 71053.0 71655.0 77814.0 65544.0 76344.0 True False 74046.70734180468 69672.0525644661 67084.46121873672 71190.17395430092 68688.42309233842 66610.04467773007 78032.15618587176 65789.63428783356 69008.52202927193 73671.21979730518 1.0050968009696675 0.9457160171388207 0.9105925136479225 0.966322726163209 0.9323644060913319 0.9041528681213257 1.0591945728680074 0.8930167637897598 0.9367093719791537 1.0 16.168813509522437 NSGEPLPPKPGPGS(ph)PSHPGALDLDGVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSGEPLPPKPGPGSPSHPGALDLDGVSR 28 1 A1X283;G3V144;A0A1B0GUF2 A1X283 SH3PXD2B SH3 and PX domain-containing protein 2B 1 NSGEPLPPKPGPGS(0.973)PS(0.026)HPGALDLDGVS(0.001)R 54.66 0.0014506999999999999 10434000.0 50043.0 48953.0 44813.0 56825.0 53300.0 44401.0 55519.0 49429.0 49052.0 45391.0 True False 58514.29150569659 53812.73032089372 45881.51187424888 53641.27947913567 42856.24761725142 42072.53339650673 50259.83839724823 48131.54112435457 49769.292702733146 53620.028985041725 1.0912767600707602 1.0035938312511123 0.8556786100777445 1.0003963163485023 0.799258195649371 0.7846421233424478 0.937333294080634 0.897641087396311 0.9281847407545637 1.0 15.710484378738716 -5.009810920510697 2.8618581345166594 0.8937564155642124 1.0919450519674574 0.4353969891113132 0.06973535335645624 0.2611481847030914 3.9624480584171287 0.018448374983922742 0.09432969469888633 9.776627749317703e-06 5.009810920510697 0.19818863640324502 NSGEPLPPKPGPGS(ph)PSHPGALDLDGVSR ddPTM_PC-9_Lapatinib_30min_R1 5 NSGEPLPPKPGPGSPSHPGALDLDGVSR 28 1 A1X283;G3V144;A0A1B0GUF2 A1X283 SH3PXD2B SH3 and PX domain-containing protein 2B 1 NSGEPLPPKPGPGS(0.951)PS(0.048)HPGALDLDGVSR;NS(0.001)GEPLPPKPGPGS(0.822)PS(0.176)HPGALDLDGVS(0.001)R;NSGEPLPPKPGPGS(0.616)PS(0.384)HPGALDLDGVSR;NSGEPLPPKPGPGS(0.956)PS(0.043)HPGALDLDGVSR;NSGEPLPPKPGPGS(0.861)PS(0.139)HPGALDLDGVSR 78.484 8.7236e-06 47468600.0 123736.0 114939.0 126025.0 111925.0 121206.0 124723.0 105742.0 111160.0 121986.0 103580.0 True False 121971.50194959644 114672.86580733114 115663.71097056806 120156.33787085487 114076.90138016464 119388.88803351343 111216.80336042038 116324.89940953105 108246.65211047245 121483.66498832585 1.0040156589062197 0.943936502231397 0.9520927030122357 0.9890740280382673 0.9390307856708721 0.9827567191439794 0.9154877190370238 0.9575353148977639 0.8910387427056516 1.0 16.890402812756207 -7.254761217223023 24.975646223231237 0.9374767203160803 0.9662205999848925 0.14018578033622653 0.03257478120402116 951.4520168055918 3558338.4708515657 0.011746223677480508 0.008890660030698815 5.562099872900189e-08 7.254761217223023 0.0287438796688122 NSGEPLPPKPGPGSPS(ph)HPGALDLDGVSR ddPTM_PC-9_AZD4547_30min_R2 2 NSGEPLPPKPGPGSPSHPGALDLDGVSR 28 1 A1X283;G3V144;A0A1B0GUF2 A1X283 SH3PXD2B SH3 and PX domain-containing protein 2B 1 NSGEPLPPKPGPGS(0.338)PS(0.649)HPGALDLDGVS(0.013)R;NS(0.001)GEPLPPKPGPGS(0.301)PS(0.698)HPGALDLDGVS(0.001)R 68.158 0.00013595 8330300.0 28073.0 25468.0 25942.0 42469.0 33100.0 32356.0 25361.0 36988.0 27076.0 32075.0 True False 36999.630045325575 33700.03294611556 25597.992129798313 32678.42818950927 28504.636347589145 30332.774205067184 27618.079869233025 31272.354499683664 28507.18208325045 30952.064012870167 1.195384903247188 1.088781443851459 0.8270205217705165 1.0557754137469237 0.9209284503849773 0.9799919705663094 0.8922855631776013 1.010347952455782 0.9210106980716015 1.0 14.917747997126172 -5.0297309317906596 5.727894076533455 0.9526542866703035 1.1734333441374176 0.6197277357091966 0.0624368514898234 0.08998109261123714 9.341123966502082 0.014561095701414388 0.04482743321234285 9.33832679933098e-06 5.0297309317906596 0.22077905746711413 NSGEPLPPKPGPGSPS(ph)HPGALDLDGVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSGEPLPPKPGPGSPSHPGALDLDGVSR 28 1 A1X283;G3V144;A0A1B0GUF2 A1X283 SH3PXD2B SH3 and PX domain-containing protein 2B 1 NS(0.003)GEPLPPKPGPGS(0.412)PS(0.582)HPGALDLDGVS(0.003)R 44.81100000000001 0.014119999999999999 9747800.0 22594.0 19915.0 15692.0 26195.0 23551.0 18871.0 21860.0 16687.0 20004.0 13602.0 True False 26418.717948158755 21892.02958635015 16066.156792241407 24727.379075335844 18936.350612268074 17881.371539503118 19789.262547305352 16248.983931337983 20296.52065615009 16067.934926627247 1.644188756601107 1.3624669060659067 0.999889336470806 1.5389270113584077 1.1785180048798545 1.1128605898117438 1.2315996198435708 1.0112677208077752 1.2631692092874591 1.0 13.97189690330074 -1.52287874567267 0.8162632936959199 1.1632412126069627 135.6904777620068 0.4667290091245416 0.1558577210671055 495.04059103450084 1.6040178567793082 0.05388641333040698 123330.07589538205 0.029999999972898636 1.52287874567267 134.52723654939982 NSGEPLPPKPGPGSPS(ph)HPGALDLDGVSR ddPTM_PC-9_Lapatinib_30min_R1 1 NSGEPLPPKPGPGSPSHPGALDLDGVSR 28 1 A1X283;G3V144;A0A1B0GUF2 A1X283 SH3PXD2B SH3 and PX domain-containing protein 2B 1 NSGEPLPPKPGPGS(0.238)PS(0.762)HPGALDLDGVSR 74.675 1.4648e-05 4635100.0 18756.0 15860.0 15189.0 15952.0 15583.0 17622.0 12789.0 12908.0 16073.0 11548.0 True False 18488.536000570843 15823.277144435498 13940.219051235536 17125.163294312035 14666.438577356765 16868.348138888363 13451.151842942403 13507.75280297075 14262.689483806536 13544.05641325723 1.3650663757184178 1.1682819874367412 1.0292499252727958 1.2644043092990616 1.0828689817771964 1.2454428440195537 0.9931405653166144 0.9973195910310189 1.0530589247875468 1.0 13.725372266973975 -1.5228787452833603 0.19844857517747885 0.980533363224346 2.414890515764813 0.4779575957289506 0.09099692751438175 51.044785264834715 0.6136955889409763 0.17502345515774295 22.710988660822867 0.029999999999791197 1.5228787452833603 1.4343571525404668 NSGS(ph)DGSPSPLLAR ddPTM_PC-9_AZD4547_30min_R2 1 NSGSDGSPSPLLAR 14 0 Q9HCH0;H7C1V4;Q9HCH0-2 Q9HCH0 NCKAP5L Nck-associated protein 5-like 1 NS(0.001)GS(0.744)DGS(0.008)PS(0.247)PLLAR 121.92 6.5204e-05 7729000.0 8473.8 9472.5 13066.0 23387.0 17223.0 20007.0 15090.0 19473.0 13698.0 18162.0 True False 11168.292134010617 12534.300380166465 12892.736302827258 17995.488475548125 14831.883740620173 18755.959127233866 16432.980766796514 16463.895295023784 14422.048314978752 17526.153908082564 0.6372357673328498 0.7151768976755364 0.7356283854657635 1.026779096539208 0.846271453417976 1.0701697146790519 0.9376261815901371 0.9393900898833887 0.8228872341653758 1.0 14.097221812810435 -5.652089168863482 5.335011906145369 0.9462984469546318 0.6882964255930635 0.7156179647335337 0.07347329752296158 0.1076085715806989 4.605196681879267 0.019655891631137845 0.034543424036151266 2.2279776563936403e-06 5.652089168863482 -0.25800202136156836 NSGSDGSPS(ph)PLLAR ddPTM_PC-9_AZD4547_30min_R2 1 NSGSDGSPSPLLAR 14 0 Q9HCH0;H7C1V4;Q9HCH0-2 Q9HCH0 NCKAP5L Nck-associated protein 5-like 1 NSGS(0.001)DGS(0.01)PS(0.989)PLLAR 144.15 0.00017279 9424400.0 14657.0 16330.0 23467.0 38150.0 21791.0 28552.0 25702.0 33880.0 30146.0 26640.0 True False 19317.621115461017 21608.35314944506 23155.812246934598 29355.106911624447 18765.695790039732 26766.63892641484 27989.42820862848 28644.624484948672 31739.456015721214 25707.34170858493 0.7514437445319337 0.840551831239283 0.9007470515398233 1.1418958538922503 0.7299741841363923 1.0412060192702133 1.0887717806809039 1.1142585184287197 1.234645587844731 1.0 14.64989281422039 -6.963357289279047 9.129878696713048 1.1113721526231992 0.8871159552320383 0.47806346311974157 0.11768337349386107 0.2899558707925079 67.71050497781012 0.04224415228441548 0.03714550608569985 1.0880346109611609e-07 6.963357289279047 -0.22425619739116087 NSGSDGSPS(ph)PLLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSGSDGSPSPLLAR 14 0 Q9HCH0;H7C1V4;Q9HCH0-2 Q9HCH0 NCKAP5L Nck-associated protein 5-like 1 NSGS(0.003)DGS(0.017)PS(0.98)PLLAR 87.99 0.005892499999999999 7639800.0 18455.0 18114.0 21590.0 31902.0 34762.0 31561.0 28405.0 31584.0 31685.0 17917.0 True False 21579.066997135065 19912.238208744486 22104.787480530966 30114.6343676795 27950.63564110495 29905.885600034868 25714.272765608817 30754.95346601418 32148.33318286917 21165.210269106054 1.0195536317743605 0.9408003962903937 1.0443925290360272 1.422836531496053 1.320593336221341 1.412973706369797 1.2149311270081182 1.4530899090998335 1.5189234018522701 1.0 14.36940720095748 -5.6837643621961345 5.338423271401878 1.351024360992611 0.9852741424937226 0.5443223101588758 0.13955332417982058 0.13810495648168122 6.814984358675071 0.03634507374668215 0.063490147445418 2.0712648627675374e-06 5.6837643621961345 -0.36575021849888834 NSGSDGSPS(ph)PLLAR ddPTM_PC-9_Lapatinib_30min_R1 2 NSGSDGSPSPLLAR 14 0 Q9HCH0;H7C1V4;Q9HCH0-2 Q9HCH0 NCKAP5L Nck-associated protein 5-like 1 NSGS(0.215)DGS(0.004)PS(0.78)PLLAR;NSGS(0.009)DGS(0.014)PS(0.976)PLLAR 168.47 6.4738e-05 15062100.0 114210.0 103170.0 109984.0 87305.0 103990.0 89922.0 82040.0 81811.0 103863.0 72557.0 True False 112581.34445645117 102931.11620374599 100941.54007051753 93725.70094094255 97873.51265220634 86076.24567842024 86287.62977519713 85612.23772573919 92164.85521412306 85098.38077387479 1.3229551894248692 1.20955434483832 1.1861746269737083 1.101380544360679 1.1501219149196023 1.0114909930794553 1.0139749897766261 1.0060383869492164 1.0830388824791561 1.0 16.376844060559094 -4.176740499582657 0.3932387286609421 1.006759455575145 1.7209415942818054 0.8721814428126166 0.03668413101578598 3.063185498661307 0.2600041850688157 0.029824434255300934 1.1316509275703934 6.656707901962618e-05 4.176740499582657 0.7141821387066605 NSGSSQGLGGS(ph)PGSHSHTTMANK ddPTM_PC-9_AZD4547_30min_R2 4 NSGSSQGLGGSPGSHSHTTMANK 23 0 Q9Y3L3;Q6ZT62-2;Q6ZT62;Q9Y3L3-2 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 NSGSSQGLGGS(0.582)PGS(0.21)HS(0.077)HT(0.029)T(0.102)MANK;NS(0.001)GS(0.004)S(0.01)QGLGGS(0.94)PGS(0.018)HS(0.001)HT(0.012)T(0.012)MANK;NSGSSQGLGGS(0.579)PGS(0.217)HS(0.145)HT(0.029)T(0.029)MANK;NS(0.002)GS(0.012)S(0.029)QGLGGS(0.816)PGS(0.13)HS(0.005)HT(0.003)T(0.003)MANK 56.573 0.0058677 16124900.0 2688.9 4826.84 61915.7 128557.0 84256.8 88371.4 34058.9 116081.0 50845.7 79066.6 True False 3543.914267405549 6387.021635999229 61094.6573630003 98920.16983585064 72559.19769823395 82845.52238798582 37090.07611916802 98143.3487260134 53533.299898446116 76298.50239999991 0.04644801871505086 0.08371096987611695 0.8007320647357866 1.2964890099317434 0.9509911127460614 1.0858079750197813 0.48611800956093293 1.2863076684191053 0.7016297596222043 1.0 16.219367119423183 -5.304311102861232 3.850178277812629 0.9722327444936378 0.04566917058756379 0.7059655979201076 0.23067843535928123 0.10721560707800644 3.3824769378678172 0.05895636123197557 0.14431146929981326 4.962367194855269e-06 5.304311102861232 -0.926563573906074 down NSGSSQGLGGS(ph)PGSHSHTTMANK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSGSSQGLGGSPGSHSHTTMANK 23 0 Q9Y3L3;Q6ZT62-2;Q6ZT62;Q9Y3L3-2 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 NSGS(0.002)S(0.004)QGLGGS(0.948)PGS(0.045)HSHTTMANK;NS(0.001)GS(0.001)S(0.002)QGLGGS(0.769)PGS(0.19)HS(0.021)HT(0.009)T(0.009)MANK 75.191 0.00027629 3834700.0 8192.66 9170.0 41323.0 39077.0 61849.0 54911.0 42428.0 30775.0 40141.0 24564.4 True False 9579.515525589188 10080.336997581264 42308.29703835018 36887.64237934335 49730.132436761465 52031.37049470911 38408.91268788068 29967.188858807847 40727.98618568886 29017.73126831659 0.33012627475976086 0.34738542804645856 1.458015330252406 1.2712104209063246 1.7137843057723812 1.7930888536251721 1.3236359635674888 1.032719911205737 1.4035551507832134 1.0 14.824647107227797 -5.259127362551317 24.669516747609343 1.3972310629689162 0.33875570032391233 0.749348186544889 0.23932224657998197 79.55264313009503 848819.7253744225 0.06562466755707849 0.15734100272072293 5.506461885095157e-06 5.259127362551317 -1.0584753626450039 NSILAQVLDQSAR ddPTM_PC-9_Lapatinib_30min_R1 2 NSILAQVLDQSAR 13 0 K7ESJ4;O14737;O14737-2;K7EQA1 K7ESJ4 PDCD5 Programmed cell death protein 5 0 ; 184.96 0.00022438 5589500.0 32033.0 29343.0 30788.0 31034.0 34117.0 31269.0 29273.0 25016.0 29396.0 25607.0 False True 31576.203545867265 29275.058086328536 28256.72948511685 33316.34388638913 32110.305136602754 29931.697761599156 30788.612706110955 26178.334685397924 26085.112926396876 30033.13583081727 1.0513788411487368 0.9747586216517935 0.9408517859837455 1.1093195220794403 1.0691625848691457 0.996622461610751 1.0251547783604562 0.8716483963867702 0.8685444328337738 1.0 14.874267497514031 -7.7530043913819 24.9372907913769 0.9025723080308755 1.0227869694511564 0.44309027542612867 0.05636728299540698 150.69601241644014 445522.99390060746 0.02779789595763241 0.015711690367779654 1.7660199634311576e-08 7.7530043913819 0.12021466142028092 NSIQFT(ph)DGYEVK ddPTM_PC-9_Lapatinib_30min_R1 1 NSIQFTDGYEVK 12 0 B4DG22;B1AXG1;B7ZB17;P51812;A0A2R8Y603 B4DG22 RPS6KA3 Ribosomal protein S6 kinase alpha-3 1 NS(0.075)IQFT(0.719)DGY(0.207)EVK 105.66 0.004314 7197200.0 12632.0 39288.0 35173.0 33670.0 43514.0 35745.0 44621.0 33065.0 35213.0 44720.0 True False 12451.865363574912 39197.0310498475 32281.211711706364 36146.20411982739 40954.59207181559 34216.26967566479 46931.257047770196 34601.320609717055 31246.941130671283 52449.79241434561 0.23740542698829037 0.7473248080792532 0.6154688174300017 0.6891581921674297 0.7808342070885689 0.6523623469347851 0.8947844192979869 0.659703671205631 0.595749567201812 1.0 15.678649442468545 -4.759843146674637 24.98806234792256 0.7249522052138548 0.2374048220166754 0.6022646407393022 0.12149297410456543 27.151037545043536 424897.6070281542 0.02841032846976655 0.1752553693032676 1.7384285803779824e-05 4.759843146674637 -0.48754738319717944 NSIQFTDGY(ph)EVK ddPTM_PC-9_AZD4547_30min_R2 1 NSIQFTDGYEVK 12 0 B4DG22;B1AXG1;B7ZB17;P51812;A0A2R8Y603 B4DG22 RPS6KA3 Ribosomal protein S6 kinase alpha-3 1 NS(0.283)IQFT(0.162)DGY(0.555)EVK 96.03399999999999 0.0063942 7634400.0 45506.0 47085.0 34865.0 19839.0 28239.0 38394.0 49478.0 42394.0 51750.0 32849.0 True False 59975.96141639959 62304.305452640576 34402.667319613676 15265.425059494555 24318.502290621425 35993.217110562175 53881.446148413386 35842.981417205265 54485.39935028112 31698.966508457448 1.892047849585181 1.9654995829601405 1.0852930271538936 0.481574850568761 0.7671701941491728 1.1354697352974898 1.6997855792565837 1.1307302844602891 1.7188383518984487 1.0 14.952148184033092 NSIQFTDGY(ph)EVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSIQFTDGYEVK 12 0 B4DG22;B1AXG1;B7ZB17;P51812;A0A2R8Y603 B4DG22 RPS6KA3 Ribosomal protein S6 kinase alpha-3 1 NS(0.139)IQFT(0.086)DGY(0.775)EVK 112.85 0.0013118000000000001 6171200.0 64468.0 101200.0 62409.0 68927.0 61487.0 45863.0 58101.0 50291.0 46580.0 48542.0 True False 75381.15909895982 111246.46719249977 63897.0672474505 65065.243654349135 49439.06373812271 43457.86354280279 52597.25266518701 48970.91453771906 47261.14437929766 57342.28034173945 1.3145825148514343 1.9400426095633216 1.1143098402548148 1.1346818310430555 0.8621747067518697 0.75786772489356 0.9172508025792874 0.8540105877525265 0.8241936682259262 1.0 15.807311657206093 -5.604022169381173 1.9083252477238555 0.8725051109543023 1.6247307986432447 0.7060622264326492 0.17971838349206207 0.16456413512306275 1.1937893904185946 0.05018947560334199 0.12107869426872933 2.488730273107736e-06 5.604022169381173 0.7522256876889424 NSKELSDT(ph)MTKT(ph)ER ddPTM_PC-9_Lapatinib_30min_R1 1 NSKELSDTMTKTER 14 2 Q96DR7;Q96DR7-4 Q96DR7 ARHGEF26 Rho guanine nucleotide exchange factor 26 2 NS(0.013)KELS(0.165)DT(0.762)MT(0.256)KT(0.804)ER 41.227 0.043761 1835900.0 19421.0 25690.0 21534.0 19743.0 19835.0 20531.0 19649.0 19653.0 22381.0 18336.0 True False 19144.052978624783 25630.516383388887 19763.55764364384 21194.96608071731 18668.344297110394 19652.936990098566 20666.32907670462 20566.150126803845 19860.216097621742 21505.353168815782 0.8901994228295192 1.1918202961928044 0.9190064207967686 0.9855669848496813 0.8680789453009662 0.913862554863626 0.9609853376726776 0.956327011482246 0.9235010437503719 1.0 14.392408203494899 NSKYEYDPDIS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 1 NSKYEYDPDISPPR 14 1 Q9BRD0;H7C462 Q9BRD0 BUD13 BUD13 homolog 1 NSKYEYDPDIS(1)PPR 107.63 0.0036772 5548600.0 22909.0 13708.0 25227.0 52373.0 40205.0 27317.0 17762.0 23669.0 20097.0 25879.0 True False 30193.585463198215 18138.842925449655 24892.473496971026 40299.2140047839 34623.22973881635 25608.863671647312 19342.78359044663 20011.499909511538 21159.286391161324 24972.984086954555 1.209049962073648 0.7263386250634367 0.9967760925285022 1.6137123967429865 1.3864274136506942 1.0254626993105294 0.7745483488515479 0.8013259384554364 0.8472870649933486 1.0 14.608080602506613 -7.021499369577333 5.994567727173639 0.8455252738613112 1.1776232363455819 0.3251900516712841 0.22411642588852235 0.2391333721705613 30.36563007484594 0.09478679300462949 0.07660497792970777 9.517012296031933e-08 7.021499369577333 0.3320979624842707 NSKYEYDPDIS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 1 NSKYEYDPDISPPR 14 1 Q9BRD0;H7C462 Q9BRD0 BUD13 BUD13 homolog 1 NSKY(0.009)EY(0.094)DPDIS(0.896)PPR 72.932 0.010214 12961000.0 100280.0 47626.0 61113.0 54530.0 42810.0 46729.0 31856.0 26064.0 55843.0 34914.0 True False 98849.98881090019 47515.72492313274 56088.52504300203 58540.318106747465 40291.999967698335 44730.509600619385 33505.34780739488 27275.02859131001 49553.373287140465 40948.83838001928 2.413987617757025 1.1603680788737032 1.3697220058474249 1.4295965507854755 0.9839595349146352 1.0923511232603205 0.8182246220626271 0.6660757586866903 1.2101289132372486 1.0 15.321534906210472 -1.5228787452803376 0.7169402025069608 0.979421433991157 183.3652814923665 0.7532591655133974 0.22675951931888275 159.81870771821727 0.7918925957114544 0.09015931872392459 46854.833873470656 0.029999999999999995 1.5228787452803376 182.38586005837536 up NSLDASRPAGLS(ph)PTLTPGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSLDASRPAGLSPTLTPGER 20 1 G5E9M9;A0A075B6E4;A0A0A6YYI5;G5E9M7;Q14135-5;Q14135-6;Q14135-2;Q14135;Q14135-4;F8W708;E7ERW0;E7EQU6;E7EWF5 G5E9M9 VGLL4 Transcription cofactor vestigial-like protein 4 1 NSLDAS(0.003)RPAGLS(0.995)PT(0.001)LT(0.001)PGER 144.33 0.0011574000000000003 5311200.0 13538.0 11341.0 13197.0 10458.0 13431.0 11433.0 16828.0 11844.0 12158.0 13269.0 True False 15829.71601231181 12466.859529942101 13511.666529901207 9872.072165293463 10799.291965240223 10833.433353353776 15233.93001583049 11533.107549755317 12335.787749323761 15674.564662653802 1.009898287639699 0.7953560305024372 0.8620122357907705 0.6298147589907009 0.6889691801757406 0.6911473196551035 0.9718885559945938 0.7357848717313397 0.7869939621809716 1.0 13.936137754458608 -9.904235758788762 14.59308804600674 0.9999976439609755 0.7908990754533364 0.21409222416266094 0.11624796417134627 0.0 0.0 0.11495816582885586 0.027881450602331978 1.2467065500369969e-10 9.904235758788762 -0.20909856850763908 NSLDASRPAGLS(ph)PTLTPGER ddPTM_PC-9_Lapatinib_30min_R1 1 NSLDASRPAGLSPTLTPGER 20 1 G5E9M9;A0A075B6E4;A0A0A6YYI5;G5E9M7;Q14135-5;Q14135-6;Q14135-2;Q14135;Q14135-4;F8W708;E7ERW0;E7EQU6;E7EWF5 G5E9M9 VGLL4 Transcription cofactor vestigial-like protein 4 1 NSLDAS(0.001)RPAGLS(0.534)PT(0.179)LT(0.285)PGER 51.577 0.019814 8078100.0 30538.0 19130.0 26566.0 20780.0 26572.0 26390.0 29092.0 25033.0 22832.0 21106.0 True False 30102.522520016675 19085.705660343705 24381.846027725544 22308.230520047888 25009.08720256202 25261.361218094655 30598.241411750754 26196.124567459472 20260.419728381185 24754.14397802277 1.2160599270466514 0.7710105296829646 0.9849601767434268 0.9011917576246461 1.0102990119458621 1.0204901951173186 1.2360856202063175 1.058252088648952 0.8184657787548135 1.0 14.595382439937604 -6.5212661803117 3.897069515839732 1.042161767125455 0.9549689691060723 0.027589817962924923 0.14004456571071472 0.6399236556607059 21.93577291363918 0.04637614487976676 0.04921178543038819 3.0111599101059977e-07 6.5212661803117 -0.08719279801938273 NSLDASRPAGLSPTLT(ph)PGER ddPTM_PC-9_AZD4547_30min_R2 1 NSLDASRPAGLSPTLTPGER 20 1 G5E9M9;A0A075B6E4;A0A0A6YYI5;G5E9M7;Q14135-5;Q14135-6;Q14135-2;Q14135;Q14135-4;F8W708;E7ERW0;E7EQU6;E7EWF5 G5E9M9 VGLL4 Transcription cofactor vestigial-like protein 4 1 NS(0.016)LDAS(0.219)RPAGLS(0.276)PT(0.091)LT(0.398)PGER 60.938 0.0091573 29161000.0 51379.0 49368.0 77413.0 125160.0 110280.0 77479.0 55356.0 105120.0 62948.0 97406.0 True False 67716.45325041075 65325.24055614229 76386.45303924427 96306.29570272379 94969.52557136356 72634.22588188894 60282.57676121857 88876.1194172906 66275.30276911106 93995.84558807912 0.720419640110124 0.6949800828689717 0.8126577569608232 1.0245803428884488 1.0103587555087428 0.7727386825179077 0.641332352340302 0.9455324207282005 0.7050875743971852 1.0 16.520309373766054 -5.393784606228816 4.564066181849794 0.8647160879544348 0.7095675159701057 0.20868523620279567 0.12503864778986962 0.3747477594956064 12.07588843431818 0.03499858119400865 0.07621048224514854 4.038456355927376e-06 5.393784606228816 -0.15514857198432908 NSLDASRPAGLSPTLT(ph)PGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSLDASRPAGLSPTLTPGER 20 1 G5E9M9;A0A075B6E4;A0A0A6YYI5;G5E9M7;Q14135-5;Q14135-6;Q14135-2;Q14135;Q14135-4;F8W708;E7ERW0;E7EQU6;E7EWF5 G5E9M9 VGLL4 Transcription cofactor vestigial-like protein 4 1 NS(0.003)LDAS(0.072)RPAGLS(0.347)PT(0.099)LT(0.479)PGER 50.88399999999999 0.033576 10384000.0 28567.0 25550.0 23829.0 28471.0 30550.0 24293.0 28176.0 32561.0 29282.0 20270.0 True False 33402.82887603128 28086.43514593253 24397.17373198573 26875.86217422741 24563.946805009964 23019.032314617623 25506.96530342523 31706.308251231272 29710.193853898556 23944.790542768293 1.3949935714146167 1.1729664160463946 1.0188927603442355 1.1224095749020595 1.025857660401572 0.961337802203901 1.065240694332519 1.3241422260345093 1.2407790245996329 1.0 14.54742419519306 -4.806395521481362 3.333622832141218 1.0987773542587618 1.4261759624105272 0.4177611919461698 0.10648488743504726 0.322942620973961 5.794190188063317 0.02983830063507819 0.2642853971993151 1.5617246979533114e-05 4.806395521481362 0.32739860815176547 NSLES(ph)ISSIDRELSPEGPGK ddPTM_PC-9_AZD4547_30min_R2 1 NSLESISSIDRELSPEGPGK 20 1 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 NS(0.025)LES(0.498)IS(0.345)S(0.131)IDRELSPEGPGK 53.536 0.013704 2375800.0 6929.1 7965.3 7140.6 9417.8 6051.7 8170.9 7610.5 8453.5 6729.8 7393.9 True False 9132.409665766594 10539.927455068884 7045.910978414847 7246.67171355954 5211.525914945773 7659.9723313197965 8287.819756507946 7147.205817104889 7085.5234888410005 7135.041811528002 1.279937792517413 1.4772061234511127 0.9875080153042485 1.0156453045378346 0.7304128066251235 1.0735707699629273 1.16156568881172 1.0017048261100916 0.9930598412742312 1.0 12.800706168617836 -5.269884228328441 24.8128243552759 0.9954750267083832 1.378571961591186 0.6545900564492606 0.11132649350681185 304.08889489460665 893481.8765636708 0.030464872554918993 0.06508303985336637 5.371749742344425e-06 5.269884228328441 0.38309693488280283 NSLLAGGDDDTMSVIS(ph)GISSR ddPTM_PC-9_AZD4547_30min_R2 2 NSLLAGGDDDTMSVISGISSR 21 0 Q8N3U4;Q8N3U4-2 Q8N3U4 STAG2 Cohesin subunit SA-2 1 NSLLAGGDDDT(0.025)MS(0.231)VIS(0.739)GIS(0.004)S(0.001)R;NSLLAGGDDDT(0.017)MS(0.104)VIS(0.846)GIS(0.026)S(0.007)R 143.09 0.00016416 11035600.0 45435.0 49967.0 55895.0 78807.0 77814.0 65065.0 46442.0 56517.0 42993.0 52189.0 True False 59882.38489329131 66117.8555920589 55153.79577885576 60639.263706012825 67010.86926741102 60996.475264331035 50575.24802992467 47783.59628145942 45265.52220805092 50361.87899509526 1.189041912020861 1.3128552173062904 1.0951496822473041 1.204070716104903 1.3305871545010701 1.211163611871421 1.0042367171179254 0.9488048745383995 0.8988052692088657 1.0 15.620044490373159 -7.321718739753774 3.3509514037369565 0.9478514950386006 1.2277129629059156 0.7946137266250999 0.06541362304275898 0.11252859927410841 2.521898352677972 0.0302589841177407 0.019930513183158475 4.767396356666981e-08 7.321718739753774 0.27986146786731503 NSLLAGGDDDTMSVIS(ph)GISSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NSLLAGGDDDTMSVISGISSR 21 0 Q8N3U4;Q8N3U4-2 Q8N3U4 STAG2 Cohesin subunit SA-2 1 NSLLAGGDDDTMS(0.003)VIS(0.979)GIS(0.017)S(0.001)R;NSLLAGGDDDTMS(0.001)VIS(0.989)GIS(0.009)S(0.002)R;NSLLAGGDDDT(0.006)MS(0.034)VIS(0.952)GIS(0.007)S(0.001)R;NSLLAGGDDDT(0.046)MS(0.046)VIS(0.786)GIS(0.09)S(0.032)R 130.17 1.2365000000000001e-06 12394900.0 48408.3 54666.6 51431.5 60086.8 69893.0 56921.0 63382.0 47411.0 53153.4 48305.5 True False 56602.86908249325 60093.53876902682 52657.82201504993 56720.33140003398 56197.968381098544 53935.962556306324 57377.99811405802 46166.51148610683 53930.667918646635 57062.904763872364 0.9919380956282763 1.053110405397259 0.9228030404857452 0.9939965663287567 0.98484240530073 0.9452018396100689 1.005521859629991 0.8090459410915889 0.9451090536279743 1.0 15.800265568140466 NSLLAGGDDDTMSVIS(ph)GISSR ddPTM_PC-9_Lapatinib_30min_R1 2 NSLLAGGDDDTMSVISGISSR 21 0 Q8N3U4;Q8N3U4-2 Q8N3U4 STAG2 Cohesin subunit SA-2 1 NSLLAGGDDDTMS(0.001)VIS(0.975)GIS(0.02)S(0.004)R;NSLLAGGDDDT(0.002)MS(0.063)VIS(0.864)GIS(0.063)S(0.009)R 135.31 5.6201999999999995e-05 7463400.0 111606.0 104699.0 106575.0 92714.0 113353.0 113095.0 99435.0 97406.0 110215.0 75631.0 True False 110014.47797396606 104456.57589818713 97812.81489139683 99532.4968448373 106685.79940057252 108258.1904873215 104583.2577608084 101931.83835808552 97801.42608459767 88703.7175780273 1.2402465305604917 1.177589606729876 1.1026912688902448 1.1220780770240502 1.202720723702786 1.2204470505093916 1.1790177527656924 1.1491270167839611 1.1025628773514218 1.0 16.43670694877696 -8.578458397243635 1.5696855704405295 1.000709742106278 1.1750223141342786 0.6613973212500465 0.03914626415236584 0.30983632946478773 1.6765713762076457 0.04127866472448866 0.012015673219042611 2.639621169826015e-09 8.578458397243635 0.17431257202800055 NSLRCIS(ph)EMNR ddPTM_PC-9_Lapatinib_30min_R1 1 NSLRCISEMNR 11 1 H0Y626;I3L073;A0A087WSX6;O95170;Q5XX13-3;Q5XX13-4;Q5XX13;Q5XX13-2 H0Y626 CDRT1;FBXW10 CMT1A duplicated region transcript 1 protein;F-box/WD repeat-containing protein 10 1 NSLRCIS(1)EMNR 63.662 0.023587999999999998 209210.0 596.95 0.0 771.42 0.0 725.96 0.0 551.97 1014.2 1112.3 445.23 True False 588.4373835327772 0.0 707.9968253673129 0.0 683.2604600922745 0.0 580.5483057900477 1061.3234345191304 987.0210609617384 522.1874122683162 1.1268701039281654 0.0 1.3558289777454882 0.0 1.3084583121685704 0.0 1.1117623522716091 2.0324569485673263 1.8901663229955 1.0 9.028423870564204 -7.542640883812211 6.169850733009821 1.702656619798071 0.6304279713917539 0.39979798155440793 0.5535731178126523 0.14382345694363458 19.668492569197205 0.23736427012637187 0.13933103229385535 2.8665473254819275e-08 7.542640883812211 -1.072228648406317 NSLS(ph)DPNIDR ddPTM_PC-9_Lapatinib_30min_R1 1 NSLSDPNIDR 10 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 NS(0.129)LS(0.871)DPNIDR 127.52 0.00031017 4089800.0 12795.0 16516.0 13567.0 13382.0 38133.0 49785.0 60675.0 59415.0 56233.0 40419.0 True False 12612.540953684369 16477.75821674001 12451.573630134479 14366.156921043359 35890.09191236252 47655.81160450331 63816.45461494492 62175.637805121405 49899.4473802584 47405.370295067856 0.2660572183104875 0.3475926485580978 0.2626616679214077 0.3030491446775607 0.7570891586537526 1.005282973382058 1.3461861856099562 1.3115737187183258 1.0526116992582597 1.0 15.532762882959878 -6.557553341358669 1.8382004050142495 1.1986762124511987 0.28499028271644367 0.9321058831373229 0.10810084355938791 0.07902834859941034 0.542194020849421 0.04176994214212151 0.044319809689685054 2.769788824450329e-07 6.557553341358669 -0.913685929734755 down NSLS(ph)PVQATQKPLVSK ddPTM_PC-9_AZD4547_30min_R2 2 NSLSPVQATQKPLVSK 16 1 E9PDI4;O00515;A0A0J9YYF6;A0A0J9YVY2;A0A0J9YW63 E9PDI4 LAD1 Ladinin-1 1 NS(0.005)LS(0.721)PVQAT(0.26)QKPLVS(0.013)K;NS(0.003)LS(0.993)PVQAT(0.004)QKPLVSK 86.54799999999999 0.0021035999999999997 95119000.0 366020.0 376730.0 408350.0 380440.0 410670.0 408360.0 448170.0 487740.0 425240.0 381710.0 True False 482406.74631104973 498500.60514332127 402935.0121888502 292735.4357394079 353655.5591801951 382825.1846452344 488056.2617796678 412370.99015020294 447717.31825533346 368346.44908348215 1.3096549390156247 1.3533471175945582 1.0939022574845805 0.7947285401224602 0.9601166512128979 1.0393073846585956 1.3249924439180751 1.1195193850144678 1.2154788497875886 1.0 18.490703809326007 -5.2899914428919095 6.413347533205027 1.0665318451569443 1.332125601390102 0.3763901386105374 0.1355192724075642 0.19344965787495835 29.141174038270368 0.03971289429326274 0.08735971501853612 5.128714892395705e-06 5.2899914428919095 0.2655937562331576 NSLS(ph)PVQATQKPLVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSLSPVQATQKPLVSK 16 1 E9PDI4;O00515;A0A0J9YYF6;A0A0J9YVY2;A0A0J9YW63 E9PDI4 LAD1 Ladinin-1 1 NS(0.037)LS(0.952)PVQAT(0.01)QKPLVSK;NS(0.205)LS(0.536)PVQAT(0.259)QKPLVSK 82.663 0.0029134 80226000.0 113178.0 114938.0 90520.0 95300.0 121091.0 86953.0 107644.0 93426.0 84015.0 70609.0 True False 132336.80003260632 126348.28504122102 92678.34009901177 89960.64996676869 97364.08780901675 82393.03160799178 97447.18104492869 90973.66649302925 85243.56043423567 83409.85275946355 1.5865847457402638 1.5147884915416752 1.111119814181624 1.0785374507996826 1.1672972027632549 0.987809340049981 1.1682934068466209 1.090682497131102 1.0219843053800868 1.0 16.347930191128754 -5.2432821078324015 3.7301334714927323 1.0814771577752733 1.5723116620264237 0.9130004950677236 0.05858322684995651 0.05436252454783171 1.6801127571444097 0.014810740023633397 0.04112026759717422 5.711075376698388e-06 5.2432821078324015 0.4908345042511504 NSLS(ph)PVQATQKPLVSK ddPTM_PC-9_Lapatinib_30min_R1 2 NSLSPVQATQKPLVSK 16 1 E9PDI4;O00515;A0A0J9YYF6;A0A0J9YVY2;A0A0J9YW63 E9PDI4 LAD1 Ladinin-1 1 NS(0.035)LS(0.965)PVQAT(0.001)QKPLVSK;NS(0.008)LS(0.961)PVQAT(0.03)QKPLVS(0.001)K 80.733 0.0036878 63010000.0 314540.0 377450.0 257800.0 220530.0 281650.0 281010.0 310350.0 240230.0 312370.0 228540.0 True False 310054.6019204278 376576.03771545895 236604.67913677805 236748.51186651466 265083.90074520523 268991.85736630484 326418.40444578737 251391.9628027324 277187.60119807447 268042.8344895916 1.1567352752064244 1.404909922074719 0.8827121963074364 0.8832487998320577 0.9889609668170358 1.003540564247951 1.2177844823472144 0.937879810446842 1.0341168109414167 1.0 18.03210404290985 -5.262807070267766 24.9995837334645 0.9955766243727249 1.2808226019403852 0.544447838484976 0.10510406475231426 86.88798256008361 1588234.0190560957 0.02804912251631222 0.06398796178446063 5.460003608543774e-06 5.262807070267766 0.28524597756766035 NSLS(ph)PVQATQKPLVSKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSLSPVQATQKPLVSKK 17 2 E9PDI4;O00515;A0A0J9YYF6;A0A0J9YVY2;A0A0J9YW63 E9PDI4 LAD1 Ladinin-1 1 NS(0.259)LS(0.73)PVQAT(0.012)QKPLVSKK 59.339 0.012528000000000001 7170600.0 27825.0 11768.0 13010.0 24713.0 27368.0 29205.0 26022.0 33512.0 30611.0 28068.0 True False 32535.222931199292 12936.249267997404 13320.207740699756 23328.410730627023 22005.436862831844 27673.43838753582 23557.007777034753 32632.345508899056 31058.627964677555 33156.50621383426 0.9812621004569009 0.3901571891974513 0.4017373741007132 0.7035847076340465 0.6636838248551733 0.8346307119653433 0.7104791929858338 0.9841913167341949 0.9367280063940697 1.0 15.017004373912382 -7.265474702512464 0.7951823224818023 0.9954831142335274 0.584765898569752 0.4242074702231682 0.1651461666507725 0.6084738346357447 0.752642075577973 0.13536511887661115 0.08216032196462847 5.426568599630396e-08 7.265474702512464 -0.4107172156637754 NSLVTGGEDDRMS(ph)VNSGSSSSK ddPTM_PC-9_AZD4547_30min_R2 1 NSLVTGGEDDRMSVNSGSSSSK 22 1 Q68DW7;Q8WVM7-2;Q8WVM7 Q68DW7 DKFZp781D1416;STAG1 Cohesin subunit SA-1 1 NSLVTGGEDDRMS(0.919)VNS(0.027)GS(0.035)S(0.008)S(0.008)S(0.002)K 72.035 0.0052863 0.0 6581.2 6370.6 11154.0 12454.0 12935.0 11544.0 8845.0 12231.0 7991.8 10984.0 True False 8673.88470253613 8429.771866127056 11006.090672105867 9582.922712381933 11139.198524352438 10822.151855090107 9632.187864964557 10340.97999041934 8414.230232416932 10599.453503269395 0.8183331999013606 0.7953024996549961 1.0383639749644682 0.9040959243253519 1.0509219669595757 1.0210103616900645 0.9087438198576478 0.9756144491062366 0.7938362322002326 1.0 13.371702262408865 -5.245871083457379 24.787299827324517 0.9620766679504361 0.806817814429122 0.4169360403330197 0.07320115263618435 688.1203738811809 1095596.607471582 0.01834315444146507 0.04814584071717072 5.677131010992946e-06 5.245871083457379 -0.15525885352131408 NSMPT(ph)VSFLDQDQSPPR ddPTM_PC-9_Lapatinib_30min_R1 1 NSMPTVSFLDQDQSPPR 17 0 A7KAX9;A7KAX9-2 A7KAX9 ARHGAP32 Rho GTPase-activating protein 32 1 NS(0.002)MPT(0.495)VS(0.495)FLDQDQS(0.008)PPR 80.17 0.022604 5872700.0 18010.0 16722.0 16054.0 12903.0 16963.0 17899.0 18183.0 10605.0 13880.0 13521.0 True False 17753.1740973705 16683.28123639662 14734.102090232103 13851.929663146198 15965.26969054115 17133.501494606906 19124.4267698977 11097.7470154559 12316.688237120317 15858.08683439999 1.1195028935558362 1.0520361888930123 0.929122298553083 0.8734931147619929 1.0067588768595122 1.0804267673348993 1.2059731397366442 0.6998162597635817 0.7766818510794423 1.0 13.952931110174509 -7.773224236062908 24.99999775779729 0.8036867983509783 1.0286068242371615 0.42167583571052525 0.11289255359403344 220.4077260023395 467558.3351636559 0.06372407524610314 0.03100221635593061 1.6856824446886417e-08 7.773224236062908 0.2249200258861832 NSMPTVSFLDQDQS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 2 NSMPTVSFLDQDQSPPR 17 0 A7KAX9;A7KAX9-2 A7KAX9 ARHGAP32 Rho GTPase-activating protein 32 1 NSMPTVSFLDQDQS(1)PPR;NS(0.001)MPT(0.003)VS(0.001)FLDQDQS(0.995)PPR 119.48 8.6719e-05 18425200.0 88698.0 89373.0 101688.0 127886.0 119693.0 113229.0 96636.0 118385.0 102661.0 108845.0 True False 116902.11896698932 118261.07446572886 100339.5506782411 98403.85851900406 103075.69300157051 106148.7727304224 105236.41679126225 100091.318466666 108087.45087341468 105034.36967983954 1.1129891989005547 1.1259273971577712 0.9553020690664499 0.9368729380578351 0.9813520404393403 1.010609889448375 1.0019236285421484 0.9529387263593745 1.029067449091963 1.0 16.680501962833937 -5.256367739889035 24.966331422555932 0.9817106220642257 1.1194583152989535 0.7988343207632278 0.02727706848176838 167.64589735501673 825269.851185007 0.007271364998958697 0.01805490514715328 5.541562810861253e-06 5.256367739889035 0.1377476932347278 NSMPTVSFLDQDQS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSMPTVSFLDQDQSPPR 17 0 A7KAX9;A7KAX9-2 A7KAX9 ARHGAP32 Rho GTPase-activating protein 32 1 NSMPT(0.001)VS(0.002)FLDQDQS(0.997)PPR;NSMPTVS(0.001)FLDQDQS(0.999)PPR 100.27 0.001036 10301500.0 59156.0 60709.0 60754.0 63207.0 67929.0 67112.0 66676.0 58463.0 59816.0 52865.0 True False 69169.94241574213 66735.78830819634 62202.60577082805 59665.716709858825 54618.8000824066 63592.52857607616 60359.96658756326 56928.40819666879 60690.6958392458 62449.00602089022 1.1076227921482633 1.0686445239155946 0.9960543767505323 0.9554310070187452 0.8746144024155598 1.0183113011407006 0.9665480755189579 0.911598307547526 0.9718440645627532 1.0 15.930390988690213 -5.27834785311634 1.980237329201892 0.9529604022540784 1.1060752189204404 0.6453623755402536 0.03878054980692252 0.2277010742780507 1.6116229870751044 0.011034487550555043 0.04295106282720389 5.268077397289296e-06 5.27834785311634 0.15311481666636195 NSMPTVSFLDQDQS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 1 NSMPTVSFLDQDQSPPR 17 0 A7KAX9;A7KAX9-2 A7KAX9 ARHGAP32 Rho GTPase-activating protein 32 1 NS(0.005)MPT(0.024)VS(0.002)FLDQDQS(0.969)PPR 88.486 0.002393 3602900.0 21486.0 15166.0 16275.0 17944.0 18210.0 17244.0 15087.0 9001.6 19997.0 13939.0 True False 21179.60569995017 15130.88405879626 14936.93232331677 19263.661619429222 17138.923602237483 16506.514317727324 15868.131038742047 9419.847197956424 17744.72728225468 16348.337577449984 1.2955204527440256 0.9255304392335884 0.9136667414991461 1.1783254124872293 1.048358802296693 1.0096754021335796 0.9706265828905866 0.5761960293106287 1.0854147828908796 1.0 13.996856318593494 -7.530080111934073 24.93471712337042 0.8531655154484298 1.0483089884106978 0.17809401310915596 0.16276536063373237 256.7327037476553 888920.4056526017 0.0730776033952635 0.04230961726125017 2.9506648834062574e-08 7.530080111934073 0.19514347296226797 NSNILEDLETLR ddPTM_PC-9_Lapatinib_30min_R1 1 NSNILEDLETLR 12 0 B0YIW6;P48444;Q6P1Q5 B0YIW6 ARCN1 Coatomer subunit delta 0 147.33 0.00061958 940290.0 4594.8 4635.0 5600.0 4871.9 5502.5 5669.0 4632.7 5902.5 5572.3 4330.8 False True 4529.277309416881 4624.267942273549 5139.589616625127 5230.19577818197 5178.853768331232 5426.550085084447 4872.558538024809 6176.751698135638 4944.688895079646 5079.373009571735 0.891700078116288 0.910401329762439 1.0118551260047093 1.029693186211373 1.0195852438031292 1.0683503800288896 0.9592834644832744 1.2160460920070189 0.9734841063575591 1.0 12.31043470846902 -5.271781224931957 1.571749447624606 1.04653516562955 0.8764686793014597 0.38875370099130413 0.06735699544115317 0.48398704035446083 1.9813128293485516 0.019126705849441893 0.0942536951509018 5.3483371307387854e-06 5.271781224931957 -0.1700664863280904 NSNLVGAAHEELQQSR ddPTM_PC-9_AZD4547_30min_R2 2 NSNLVGAAHEELQQSR 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ; 111.11 0.00041623 29399000.0 45749.0 40989.0 56594.0 78636.0 71126.0 65095.0 43503.0 60107.0 52057.0 69451.0 False True 60296.230361685615 54237.89266641784 55843.5265821373 60507.685114089116 61251.382624127604 61024.59935958859 47374.68272352211 50818.844271452486 54808.62674352818 67019.54162923932 0.8996813301895151 0.8092847451340208 0.833242442794832 0.9028364510283489 0.913933177325773 0.9105493394327356 0.706878644225962 0.758269051623612 0.8178006803856779 1.0 16.03229419901507 -7.224756585214592 24.999217529913082 0.8005927381904615 0.8758126945864017 0.09358788233777715 0.07799423281985199 1010.1005761809809 688381.7868698685 0.029174548418890056 0.02259788367745324 5.959960957654437e-08 7.224756585214592 0.07521995639594015 NSNLVGAAHEELQQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSNLVGAAHEELQQSR 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ; 100.69 0.0014619000000000001 24643000.0 128666.0 107271.0 113654.0 183334.0 184602.0 168164.0 192263.0 204110.0 169238.0 148936.0 False True 150446.6125306624 117920.15595065852 116363.94239519551 173062.39035684778 148430.56327654532 159345.18380419715 174050.45677642163 198752.32877242166 171712.78558315977 175936.91782327305 0.8551167906771254 0.6702411148813473 0.6613958220643719 0.9836616015445223 0.843657858242364 0.9056949830407843 0.9892776281965656 1.1296794966708834 0.9759906431670221 1.0 17.424698717747667 -6.480870585601941 0.7852330668287951 1.0404118578320563 0.7286309388502149 0.5937133057300032 0.08978558976139993 0.4506499646342647 0.6162007884292955 0.05602587674132313 0.07406159401638782 3.3046800175384675e-07 6.480870585601941 -0.31178091898184135 NSNLVGAAHEELQQSR ddPTM_PC-9_Lapatinib_30min_R1 2 NSNLVGAAHEELQQSR 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ; 192.23 6.1322e-09 32430000.0 83779.0 78935.0 93417.0 82766.0 82538.0 88923.0 82516.0 78702.0 87188.0 83309.0 False True 82584.29609681324 78752.23085725182 85736.61486004804 88852.8877392821 77683.27711595148 85119.97057963739 86788.27472611117 82358.78223577661 77367.96930965739 97708.84964773509 0.8452079457955993 0.8059887220162081 0.8774703127623551 0.9093637685800114 0.7950485283167203 0.8711592745848122 0.8882335125119646 0.8428999270045721 0.7918215145157099 1.0 16.57620161487212 -10.547512372583094 4.43978793052322 1.0000065081782956 0.8491689578505458 0.5893698449790183 0.038172331194910765 27313635.859702982 2.2436882762957566 1968.0099277815716 0.009358906793454235 2.8345728784041005e-11 10.547512372583094 -0.15083755032774981 NSNPALNDNLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSNPALNDNLEK 12 0 O00299 O00299 CLIC1 Chloride intracellular channel protein 1 0 90.79299999999999 0.035434 0.0 10612.0 14429.0 10653.0 18245.0 16813.0 18101.0 16158.0 14876.0 17004.0 17292.0 False True 12408.402003446075 15861.415762061062 10907.007921727487 17222.791801088093 13518.613343130372 17151.751695010647 14627.39726621043 14485.520762424872 17252.651331592468 20426.902716603327 0.6074539138701787 0.7764963676636419 0.5339530947519562 0.843142596801478 0.6618043631324595 0.8396648250089045 0.7160849331465723 0.7091393621143943 0.8446043715462171 1.0 14.318182847734702 -14.522878744376296 0.12003763298420897 1.9256545805643104 0.5889936856728691 0.5224221447222941 0.08913376297830435 121.32628806934807 0.9405549939193529 27.030281527463334 0.8071364339333971 3.0000000062448973e-15 14.522878744376296 -1.3366608948914411 NSNPALNDNLEK ddPTM_PC-9_Lapatinib_30min_R1 2 NSNPALNDNLEK 12 0 O00299 O00299 CLIC1 Chloride intracellular channel protein 1 0 ; 166.24 0.0033851999999999997 19796600.0 65711.0 53465.0 57597.0 50195.0 48810.0 43917.0 58205.0 42675.0 42755.0 45727.0 False True 64773.94909007837 53341.20507737981 52861.59699084953 53886.50774561138 45939.09176415221 42038.772285527215 61218.57010074776 44657.83629274688 37939.48166989042 53630.85102260248 1.2077740303389868 0.9945992662861046 0.985656501489623 1.0047669712140341 0.8565795785114688 0.7838542831962552 1.141480489931951 0.8326893092545936 0.7074189752070313 1.0 15.710775525999663 -1.5228787452809025 0.5650057629356253 0.8877305007285548 15.974506278522645 0.38505035022881706 0.11652222950930419 158.38607014255973 1.382202508548521 0.0570304133898195 2916.2058727524395 0.029999999999960975 1.5228787452809025 15.08677577779409 NSNPVIAELSQAINS(ph)GTLLSKPSPPLPPKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSNPVIAELSQAINSGTLLSKPSPPLPPKR 30 2 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 NSNPVIAELSQAINS(0.411)GT(0.298)LLS(0.08)KPS(0.211)PPLPPKR 93.166 3.1617e-10 3019200.0 11448.0 13688.0 12835.0 16577.0 20401.0 17582.0 15627.0 13664.0 16207.0 11904.0 True False 13385.920291693421 15046.854179159465 13141.035077008566 15648.244433359132 16403.570499803885 16659.968968657933 14146.697430317507 13305.334478204719 16443.996714368346 14062.100967987844 0.9519146763464621 1.0700288821288793 0.9345001224869548 1.1127956248488131 1.1665092248410363 1.1847425222293664 1.0060159191377054 0.9461839669971157 1.1693840594519163 1.0 13.779524537946829 -5.774293470638323 24.96136711342136 1.085847738693466 0.9939359824048198 0.22638206620899204 0.08266101867482634 364.57926967255514 707975.9998607433 0.024472975775071328 0.03655922574648659 1.6815373931107262e-06 5.774293470638323 -0.09191175628864612 NSNPVIAELSQAINSGT(ph)LLSKPSPPLPPKR ddPTM_PC-9_AZD4547_30min_R2 2 NSNPVIAELSQAINSGTLLSKPSPPLPPKR 30 2 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 NSNPVIAELS(0.002)QAINS(0.13)GT(0.396)LLS(0.077)KPS(0.396)PPLPPKR;NSNPVIAELSQAINS(0.063)GT(0.329)LLS(0.329)KPS(0.279)PPLPPKR 74.65 1.2195e-06 7802900.0 15551.3 18906.7 28374.8 39462.0 34283.0 32612.0 25917.7 31158.0 26256.1 31108.0 True False 20496.289912865443 25017.92103433026 27998.53161223503 30364.645581822373 29523.397217655525 30572.766484597927 28224.32509076224 26343.247039611302 27643.94384310947 30018.918388538274 0.6827790944223783 0.8334051450662033 0.9326962167606059 1.0115169770212675 0.9834930371418064 1.0184499684129567 0.9402179227596275 0.877554837207912 0.9208840733470395 1.0 14.873584375708461 -4.905470261181565 1.8334043664068294 0.9619143781030294 0.633478893068403 0.8174799616520719 0.04156246621115586 0.29315340746126184 1.257834773280979 0.013055672813807805 0.1545051480686638 1.2431677602845675e-05 4.905470261181565 -0.3284354850346264 NSNPVIAELSQAINSGTLLSKPS(ph)PPLPPK ddPTM_PC-9_AZD4547_30min_R2 1 NSNPVIAELSQAINSGTLLSKPSPPLPPK 29 1 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 NSNPVIAELSQAINS(0.001)GT(0.003)LLS(0.027)KPS(0.969)PPLPPK 76.60600000000001 2.2023e-06 992500.0 5326.3 6573.2 10266.0 11029.0 11210.0 11605.0 9558.2 13356.0 11171.0 8493.0 True False 7019.952606077638 8697.858354068117 10129.86613231476 8486.434446351395 9653.684998685025 10879.337515447052 10408.861283313083 11292.137090347547 11761.476253951505 8195.662655068008 0.8565448459175734 1.0612757894188778 1.2360033054863093 1.0354787408317228 1.1779017030081649 1.3274506252059461 1.270045110614269 1.3778186786842368 1.4350854529961015 1.0 13.000644886888669 -3.82062378305038 0.4904204662889028 1.2961579164865618 3.0796709644237645e-12 0.4688800585507329 0.1281381173409987 9.446300965306667 0.8519590443644969 0.0764396200027302 8.641511393944336 0.00015113888603903472 3.82062378305038 -1.296157916483482 NSNPVIAELSQAINSGTLLSKPS(ph)PPLPPKR ddPTM_PC-9_Lapatinib_30min_R1 1 NSNPVIAELSQAINSGTLLSKPSPPLPPKR 30 2 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 NSNPVIAELSQAINS(0.004)GT(0.01)LLS(0.021)KPS(0.966)PPLPPKR 86.89 3.1874999999999996e-09 2088600.0 15576.0 10973.0 8418.2 8189.1 9975.4 9286.1 7961.7 6568.9 7645.7 6326.1 True False 15353.883383711434 10947.592692679107 7726.088091191726 8791.35373203678 9388.666584390978 8888.955149956375 8373.917869102712 6874.115074948448 6784.560753209711 7419.5579560016085 2.0693798033199307 1.475504707638776 1.0413138002301294 1.1848891516408384 1.2653943321241363 1.1980437652308094 1.1286275973259472 0.9264857981718496 0.9144157635053912 1.0 12.857117520877235 -4.820653591170209 2.0069290754018447 1.092928184479938 2.3108771964907855 0.8797927832633609 0.11281174045045886 0.23972145700451206 1.1405783360027586 0.03427259717670015 0.5297961471234642 1.5112851286689133e-05 4.820653591170209 1.2179490120108476 up NSNS(ph)PPS(ph)PSSMNQR ddPTM_PC-9_AZD4547_30min_R2 2 NSNSPPSPSSMNQR 14 0 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 2 NS(0.006)NS(0.989)PPS(0.889)PS(0.065)S(0.051)MNQR;NS(0.006)NS(0.994)PPS(0.768)PS(0.1)S(0.132)MNQR 106.3 0.0030866 2562600.0 13890.5 12946.2 15131.8 22506.7 21343.6 17165.1 14950.6 21449.0 15278.1 18658.8 True False 18307.39005965145 17130.805973260616 14931.14244505752 17318.128040048705 18380.40955735357 16091.763583489876 16281.174436850093 18134.549898986555 16085.669175140663 18005.56109129671 1.0167630970689736 0.9514175029814027 0.8292517166973896 0.9618210702925394 1.0208184829207045 0.8937107542440375 0.904230329413054 1.0071638316093463 0.8933722805736913 1.0 14.136154937201415 -11.030093496395551 3.065605325131338 1.0018094003106681 0.9412959083732162 0.07856902172006297 0.059472874353467466 42157913.391463645 47406788.71540306 635277.2376343883 0.014972198337433972 9.330534082570404e-12 11.030093496395551 -0.060513491937451924 NSNS(ph)PPS(ph)PSSMNQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSNSPPSPSSMNQR 14 0 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 2 NS(0.054)NS(0.945)PPS(0.881)PS(0.05)S(0.068)MNQR 99.238 0.0078292 3902000.0 26551.0 24083.0 28239.0 33699.0 34070.0 28131.0 33304.0 27323.0 28571.0 24564.0 True False 31045.559893846286 26473.80108099778 28912.32485700386 31810.954283632076 27394.22807354139 26655.76083820479 30149.204019920275 26605.8002011115 28988.7968239784 29017.25875148299 1.0698998192673743 0.9123467281224412 0.9963837419868695 1.0962770314065697 0.9440667124402766 0.9186174706059197 1.039009379836041 0.9168957146839982 0.999019137963777 1.0 14.824623614583365 NSNS(ph)PPSPSSMNQR ddPTM_PC-9_AZD4547_30min_R2 2 NSNSPPSPSSMNQR 14 0 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 NS(0.004)NS(0.996)PPSPSSMNQR;NSNS(0.988)PPS(0.004)PS(0.001)S(0.007)MNQR 127.3 2.5735e-05 42242000.0 55717.0 54923.0 68801.0 101744.0 80211.0 76389.0 63150.0 76918.0 62892.0 66606.0 True False 73433.84701440547 72675.78567219671 67888.65378622526 78288.49272913013 69075.08719264263 71612.38375419946 68770.22766223985 65032.09049980181 66216.34272343719 64274.144213288586 1.1425099145734425 1.1307157265451555 1.0562358257302067 1.218040219552921 1.0746947787188346 1.1141709412195286 1.0699516656967283 1.011792397950847 1.0302174153218373 1.0 15.971950875779692 -7.472899360803462 1.2536508112592968 1.0074721902195176 1.1274686197069566 0.5908093729756269 0.0408059723769025 0.33053266184112334 0.9831559788888727 0.028841065624632525 0.013881405071083467 3.365895583428874e-08 7.472899360803462 0.11999642948743894 NSNS(ph)PPSPSSMNQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSNSPPSPSSMNQR 14 0 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 NSNS(0.997)PPS(0.002)PSS(0.001)MNQR;NSNS(1)PPSPSSMNQR 176.43 8.992e-05 42737000.0 69229.0 74883.0 63317.0 76738.0 81922.0 63311.0 73313.0 53702.0 56678.0 54178.0 True False 80948.10236492369 82316.88935549353 64826.71741105969 72438.61864795271 65869.97218199751 59990.859707354226 66368.26189984448 52292.379401972335 57506.80852575858 64000.04252718797 1.26481325899957 1.286200541515646 1.0129167864774549 1.1318526642725266 1.0292176314416537 0.9373565600658688 1.0370034031094661 0.817067885224575 0.8985432861443647 1.0 15.965785243314318 -5.132628703150503 0.49358922659760474 0.9099441963686901 1.4779371319770265 0.7235348742506915 0.07478069720931392 1.6948138922653513 0.409085805623995 0.050612855078080055 0.5376189807396916 7.368367814314344e-06 5.132628703150503 0.5679929356083364 NSNS(ph)PPSPSSMNQR ddPTM_PC-9_Lapatinib_30min_R1 2 NSNSPPSPSSMNQR 14 0 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 NS(0.002)NS(0.997)PPSPSSMNQR;NSNS(0.997)PPS(0.002)PSSMNQR 113.37 0.00018978 26916000.0 54059.0 48346.0 47404.0 41008.0 44733.0 46761.0 43306.0 42535.0 45279.0 32420.0 True False 53288.10874679356 48234.05780736939 43506.62610473169 44023.86511867779 42101.89288846177 44761.14103521501 45548.17278211461 44511.33138165174 40179.202210992116 38023.75380306542 1.4014426093432562 1.2685243560429542 1.1441959762853358 1.1577990260164333 1.107252406127971 1.1771889032062488 1.1978873263807686 1.1706190717567528 1.0566868915439098 1.0 15.214613345142897 -4.882358941072737 1.6229565740573746 1.1343900252203847 1.4692705047975008 0.7040790109413517 0.05719891674614504 0.4543481358237883 1.3646698970591777 0.015719383879255946 0.22810073109425458 1.3111158238751023e-05 4.882358941072737 0.3348804795771161 NSNSPPS(ph)PSSMNQR ddPTM_PC-9_AZD4547_30min_R2 3 NSNSPPSPSSMNQR 14 0 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 NS(0.001)NS(0.188)PPS(0.548)PS(0.069)S(0.194)MNQR;NSNSPPS(0.613)PS(0.332)S(0.055)MNQR;NS(0.008)NS(0.041)PPS(0.807)PS(0.08)S(0.063)MNQR 113.67 0.00018641 27647000.0 20595.699999999997 19427.2 22611.4 38410.3 29531.3 26664.6 22322.1 31973.0 25439.1 22979.2 True False 27144.704182827336 25706.662480397998 22311.558061973687 29555.398768219347 25431.38874234317 24997.25834678065 24308.72365636238 27032.307516448174 26783.758891048034 22174.705202324127 1.2241292019513434 1.159278657634812 1.0061715751529006 1.3328429171235003 1.1468647952838493 1.1272870650907545 1.096236609892545 1.2190605137611896 1.2078518585329754 1.0 14.436627304550553 -11.06851839980778 7.246028041674729 0.9999152725670111 1.1660856387415042 0.273153961185268 0.08252290549865039 0.00011166615115911601 7.001944226363507e-06 0.07899165113150382 0.01914855916948303 8.540466631519189e-12 11.06851839980778 0.1661703661744931 NSNSPPS(ph)PSSMNQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 NSNSPPSPSSMNQR 14 0 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 NSNSPPS(0.81)PS(0.167)S(0.024)MNQR;NSNSPPS(0.872)PS(0.064)S(0.064)MNQR;NSNS(0.001)PPS(0.934)PS(0.045)S(0.021)MNQR;NSNSPPS(0.849)PS(0.075)S(0.075)MNQR;NSNS(0.047)PPS(0.867)PS(0.081)S(0.005)MNQR 128.82 2.157e-05 146366500.0 18393.649999999998 19726.199999999997 20694.6 29247.100000000002 27698.18 23452.0 22101.5 20146.22 17957.719999999998 16524.66 True False 21507.33165385279 21684.486770085863 21188.037748707535 27608.479807377553 22270.9204620488 22222.135835113513 20007.88591899675 19617.40307168454 18220.317682331497 19520.45004886341 1.1017846207446977 1.1108599809843245 1.085427728134845 1.4143362339632672 1.1409019979713806 1.1384028431458941 1.0249705241894114 1.0049667411652108 0.9333963938701498 1.0 14.252698694529073 -7.308987347204685 1.9236891197371417 0.9754569887118995 1.1752003263585036 0.49011575813623676 0.08875759983853933 0.3196507571286405 2.3064343624342794 0.05001228546715699 0.030363726696454003 4.90922178538695e-08 7.308987347204685 0.19974333764660412 NSNSPPS(ph)PSSMNQR ddPTM_PC-9_Lapatinib_30min_R1 5 NSNSPPSPSSMNQR 14 0 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 NSNS(0.003)PPS(0.841)PS(0.135)S(0.021)MNQR;NSNS(0.043)PPS(0.945)PS(0.011)S(0.002)MNQR;NSNS(0.026)PPS(0.538)PS(0.087)S(0.349)MNQR;NSNS(0.037)PPS(0.917)PS(0.037)S(0.008)MNQR;NS(0.002)NS(0.007)PPS(0.953)PS(0.029)S(0.009)MNQR 133.9 1.5422e-05 113630100.0 67556.0 62920.5 62567.6 52739.5 61293.8 63297.6 48536.0 58234.1 62274.9 48544.8 True False 66592.63905174696 62774.81144807398 57423.53344592041 56618.13876381451 57688.61919224733 60590.50920191241 51048.95659152806 60939.86888003401 55260.8449782308 56935.70399812 1.1696112346998613 1.10255616493557 1.008568076155105 0.9944223885540087 1.0132239551152682 1.0641917978903552 0.8966071025171426 1.0703278365021398 0.9705833264142215 1.0 15.797046020251232 -5.057400580421696 2.188217107158554 1.0021590189888214 1.175698996470918 0.595448857044912 0.045764998969168955 0.25773944684850697 2.0642483178614124 0.011822867698147792 0.06966157857914619 8.761922743982812e-06 5.057400580421696 0.17353997748209649 NSNSPPSPS(ph)SMNQR ddPTM_PC-9_AZD4547_30min_R2 2 NSNSPPSPSSMNQR 14 0 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 NSNS(0.001)PPS(0.285)PS(0.626)S(0.088)MNQR;NSNS(0.002)PPS(0.287)PS(0.356)S(0.356)MNQR 130.47 1.7063e-05 25748000.0 21946.0 20665.0 27168.0 36559.0 30614.0 29825.0 25069.0 32696.0 28051.0 27387.0 True False 28924.37149484255 27344.5571238997 26807.734568744145 28130.887380919477 26363.774536105546 27960.0380351752 27300.092434911985 27643.58447933537 29533.718592748504 26428.189465954016 1.0944514958962372 1.0346738719701625 1.014361373611275 1.0644273387383936 0.9975626431038171 1.0579626754679725 1.0329913999625737 1.045988584081671 1.117508205804078 1.0 14.689789972218673 -8.023257661240821 24.942948141892597 1.0664188633420943 1.0406164334392427 0.02045078391655386 0.036638864332087726 1950.2940636565374 2091600.8217107155 0.02268866136633346 0.008707083078905272 9.478559459040142e-09 8.023257661240821 -0.025802429902851642 NSNSPPSPS(ph)SMNQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSNSPPSPSSMNQR 14 0 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 NSNS(0.01)PPS(0.198)PS(0.396)S(0.396)MNQR;NS(0.001)NS(0.01)PPS(0.206)PS(0.464)S(0.319)MNQR 63.693999999999996 0.038333 24878100.0 17924.3 17121.1 19273.2 20391.7 25055.2 16701.5 19450.2 21041.9 19056.5 14055.4 True False 20958.529968937848 18820.76965859198 19732.746182018032 19249.21915978339 20145.81342025812 15825.643938689595 17607.736248746503 20489.572420735945 19335.165261143968 16603.532757514826 1.2622934091813642 1.1335400684576373 1.1884667239318036 1.1593447876971315 1.2133449979878557 0.9531491984154302 1.0604813147838776 1.2340489653602353 1.1645211620637057 1.0 14.019202618079097 NSNSPPSPSS(ph)MNQR ddPTM_PC-9_AZD4547_30min_R2 2 NSNSPPSPSSMNQR 14 0 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 NSNS(0.01)PPS(0.23)PS(0.047)S(0.713)MNQR;NSNS(0.013)PPS(0.3)PS(0.159)S(0.528)MNQR 78.615 0.012102 72907800.0 9529.4 8058.799999999999 10416.4 14821.2 12863.7 12276.7 10527.2 11615.6 12419.5 11589.8 True False 12559.550976166627 10663.649501576729 10278.27173004515 11404.401325257351 11077.797298624851 11509.036008262707 11464.100406111342 9820.675919934181 13075.969415088235 11184.044629660568 1.1229882741041786 0.9534698630669151 0.9190120453191621 1.0197027732715218 0.9905000977236854 1.0290584837027785 1.0250406526193623 0.8780969895174887 1.1691628429674004 1.0 13.449154402426716 -8.272659855963838 24.999614922343653 1.0845813917007547 0.991679712674894 0.20023964505086567 0.07381626495203264 1285.9784975412997 2865170.973281996 0.06527506639464627 0.017478957277873505 5.337527726458033e-09 8.272659855963838 -0.09290167902586077 NSNSPPSPSS(ph)MNQR ddPTM_PC-9_Lapatinib_30min_R1 1 NSNSPPSPSSMNQR 14 0 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 NS(0.001)NS(0.011)PPS(0.019)PS(0.155)S(0.813)MNQR 78.508 0.012213 11837000.0 5564.4 6533.5 7520.0 6554.2 6513.5 8442.5 6231.7 5588.4 6346.2 5116.0 True False 5485.050635614013 6518.372082167045 6901.734628039453 7036.217732170254 6130.388736033711 8081.433955428724 6554.346934057718 5848.057465457213 5631.42412755136 6000.293783358503 0.9141303465551155 1.0863421554866872 1.1502327847981457 1.1726455380709577 1.0216814305052895 1.3468397127224259 1.092337670571373 0.97462852263609 0.9385247341004895 1.0 12.55081742361963 -7.731828247052504 4.863353091057726 0.9656508864944076 1.121668806480624 0.27364499430386735 0.10517459140083033 0.24252399122488183 13.885040696874327 0.055107435882821944 0.02915323556079891 1.8542647952392936e-08 7.731828247052504 0.1560179199862164 NSNVSQASMSSRMVPGLPANGK ddPTM_PC-9_AZD4547_30min_R2 1 NSNVSQASMSSRMVPGLPANGK 22 1 A0A590UJW3;A0A1W2PSB2;A0A1W2PRD1;Q9NY46-3;Q9NY46 A0A590UJW3 SCN3A Sodium channel protein type 3 subunit alpha 0 61.684 0.0077896 47869000.0 3015.8 7675.8 118260.0 183490.0 125990.0 81095.0 31248.0 143650.0 40650.0 72896.0 False True 3974.761667463146 10156.85224154993 116691.79513028877 141189.21539224024 108498.46324570283 76024.11683026094 34029.01146460285 121452.1932486093 42798.676011380216 70343.93322781571 0.05650468327653063 0.14438846074551973 1.6588750411833095 2.007127109810382 1.5423997247114396 1.0807487347067928 0.4837519015946488 1.7265482277664868 0.6084202865479886 1.0 16.10213838396988 -5.248267499598912 23.741213871006863 1.2915781518295124 0.10044599648442723 0.5007298123982995 0.46385821496289076 330.4481243652381 595599.1963813968 0.12381917041928642 0.322705769422695 5.645891143410707e-06 5.248267499598912 -1.191132155345085 NSPAT(ph)PPNTLNLR ddPTM_PC-9_AZD4547_30min_R2 2 NSPATPPNTLNLR 13 0 Q92870;Q92870-4;H0YAJ5;G5E9Y1;Q92870-2;D6RB55;D6RDY3;D6RB00 Q92870 APBB2 Amyloid beta A4 precursor protein-binding family B member 2 1 NS(0.004)PAT(0.691)PPNT(0.305)LNLR;NSPAT(0.769)PPNT(0.231)LNLR 142.95 0.00010946 17630400.0 65397.0 69564.0 94850.0 133049.0 98063.0 97827.0 77514.0 107639.0 84583.0 92412.0 True False 86191.88565789757 92049.20260183679 93592.22702611102 102376.60863655894 84448.64514059314 91709.86222521664 84412.59583548475 91005.86584815187 89053.88470038309 89176.68400802382 0.9665293862030384 1.0322115430256917 1.0495145459511581 1.1480199087392333 0.9469812213806329 1.0284062840569952 0.946576975522992 1.0205118844737877 0.9986229662046003 1.0 16.4443789342795 NSPEDLGLS(ph)LTGDSCK ddPTM_PC-9_AZD4547_30min_R2 1 NSPEDLGLSLTGDSCK 16 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 NS(0.001)PEDLGLS(0.986)LT(0.013)GDSCK 115.2 0.0019687999999999997 0.0 8029.5 10724.0 11721.0 15212.0 15727.0 13316.0 14405.0 13373.0 11129.0 17314.0 True False 10582.713976024714 14190.323280750079 11565.571881634647 11705.10842305717 13543.577517780488 12483.34841496707 15687.017093817352 11306.510130968685 11717.256219696195 16707.842129971443 0.633398011167514 0.8493211253950442 0.6922241538832649 0.7005757136081568 0.8106120115586487 0.7471550376079837 0.9389014435129909 0.6767187553613789 0.701302785156028 1.0 14.028237796406549 -6.268650684004972 24.13726089653398 0.7993422701311722 0.7262930203560467 0.1490459760154822 0.1062198362147849 868.3513799076709 2906492.8444821495 0.031921259900549795 0.03697902532830371 5.387029031069138e-07 6.268650684004972 -0.0730492497751255 NSPEDLGLS(ph)LTGDSCK ddPTM_PC-9_Lapatinib_30min_R1 2 NSPEDLGLSLTGDSCK 16 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 NS(0.007)PEDLGLS(0.913)LT(0.074)GDS(0.005)CK;NSPEDLGLS(0.965)LT(0.032)GDS(0.003)CK 93.75299999999999 0.016608 0.0 12318.8 16011.5 16737.9 11686.4 14460.9 16399.6 14996.1 13044.7 11937.099999999999 12279.7 True False 12143.131653008759 15974.426355493628 15361.774472162455 12545.856840687577 13610.338293223276 15698.227337334796 15772.524681519173 13650.804384018638 10592.618094764324 14402.229783328265 0.8431424741650357 1.1091634139864444 1.0666247312582764 0.8711051711735923 0.9450160494577259 1.0899858961774622 1.0951446351576153 0.9478257595792936 0.735484591908548 1.0 13.814004569572155 -8.0072711203475 24.60929973862101 0.8590465691836513 1.0066218912670444 0.20278622438727245 0.10626474065581668 366.4146835544967 1240132.6439869746 0.06118227108962028 0.027447252846085426 9.833970013060162e-09 8.0072711203475 0.14757532208339308 NSPEDLGLSLT(ph)GDSCK ddPTM_PC-9_AZD4547_30min_R2 1 NSPEDLGLSLTGDSCK 16 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 NSPEDLGLS(0.097)LT(0.887)GDS(0.017)CK 105.39 0.0037521 0.0 9265.3 8952.4 9202.5 18178.0 12007.0 12604.0 13598.0 12075.0 9989.2 15601.0 True False 12211.472669787876 11846.088226276297 9080.468837193313 13987.342947300356 10340.035305906422 11815.86988752215 14808.195657183487 10209.086205895965 10517.208718644024 15054.813738574829 0.8111340918485439 0.7868638185753942 0.6031604903836506 0.9290943873626746 0.6868258542058366 0.784856597544375 0.9836186560874258 0.6781276994306017 0.6985944098196223 1.0 13.877937238386087 -7.009197662471325 24.883387282391364 0.8234017957694179 0.7621018509056675 0.07216496817099272 0.12464769127990016 1512.0546230912803 4090718.8082591165 0.04504260344923825 0.03762384426294667 9.790442870013873e-08 7.009197662471325 -0.061299944863750344 NSPFQIPPPS(ph)PDSK ddPTM_PC-9_AZD4547_30min_R2 4 NSPFQIPPPSPDSK 14 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 NSPFQIPPPS(0.934)PDS(0.066)K;NSPFQIPPPS(0.774)PDS(0.226)K;NSPFQIPPPS(0.86)PDS(0.14)K;NSPFQIPPPS(0.969)PDS(0.031)K 127.78 2.7718e-05 27877500.0 130393.0 128765.0 153188.0 222977.0 230899.0 212129.0 195768.0 203782.0 209033.0 239068.0 True False 171855.26165711338 170385.76811318408 151156.62702873888 171573.0976103089 198842.65945685716 198864.5400960158 213190.97274713154 172292.1743445044 220082.05763067244 230698.30208663625 0.744935095328855 0.7385653321765565 0.6552134353029336 0.7437120085343172 0.8619164409029069 0.8620112861573397 0.9241115813113786 0.7468289657363926 0.9539821300809704 1.0 17.815647860424747 -6.247521619327669 3.2118917198384507 0.8814918086015957 0.7131041947623302 0.6114615747605399 0.06690535436055021 0.17855622617029251 3.8190816107222916 0.020379950986268543 0.025612257521157488 5.655596026381698e-07 6.247521619327669 -0.16838761383926548 NSPFQIPPPS(ph)PDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSPFQIPPPSPDSK 14 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 NSPFQIPPPS(0.998)PDS(0.002)K;NSPFQIPPPS(0.852)PDS(0.147)K 131.51 1.615e-05 13416600.0 52737.0 62622.0 63681.0 88303.0 99740.0 91908.0 86337.0 103205.0 96466.0 79991.0 True False 61664.33249677116 68838.69830561981 65199.39655153736 83355.66919218872 80196.66298958076 87088.18268521292 78158.53433424994 100495.97810473651 97876.63275425763 94492.7350915922 0.652582787840776 0.7285078396650724 0.6899937491315 0.8821383899131687 0.8487071827463328 0.9216389238897359 0.8271380255687439 1.0635312652060007 1.0358111939440149 1.0 16.527915794065905 -5.999041086617955 0.409366611292807 1.039910029731194 0.570762967999678 0.8063391021005093 0.060081158978946114 0.9324424713976521 0.24651429470772895 0.05736833285668401 0.1955678013630115 1.0022104190410956e-06 5.999041086617955 -0.4691470617315161 NSPFQIPPPS(ph)PDSK ddPTM_PC-9_Lapatinib_30min_R1 4 NSPFQIPPPSPDSK 14 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 NSPFQIPPPS(0.683)PDS(0.317)K;NSPFQIPPPS(0.902)PDS(0.098)K;NSPFQIPPPS(0.99)PDS(0.01)K;NSPFQIPPPS(0.998)PDS(0.002)K 114.29 0.00017561 23642400.0 297198.0 234607.0 222559.0 266661.0 251692.0 218014.0 187340.0 187755.0 241651.0 204801.0 True False 292959.90202056203 234063.7819057108 204261.05812258393 286272.1394950184 236887.9714055112 208690.04943545623 197039.54853833994 196478.78273332573 214433.7196821586 240200.57996982106 1.2196469386434023 0.9744513603385917 0.8503770396734571 1.1918045307425393 0.9862089901501234 0.868815759985576 0.8203125428052509 0.8179779697368401 0.892727734916794 1.0 17.8738801089049 -6.6674494318771655 4.096032568151126 0.8644755978708629 1.0431592107007288 0.36779598676345804 0.10905975679613467 0.24560019533807417 7.637699230782366 0.03752265698499654 0.03700072660234343 2.1505550698159657e-07 6.6674494318771655 0.1786836128298659 NSPFQIPPPSPDS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSPFQIPPPSPDSK 14 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 NSPFQIPPPS(0.407)PDS(0.593)K;NSPFQIPPPS(0.22)PDS(0.78)K 74.33800000000001 0.018775 10048200.0 93116.0 96097.0 100206.0 151008.0 161753.0 148036.0 146719.0 161745.0 140709.0 136073.0 True False 108878.69967516829 105636.87507705213 102595.29107337112 142547.51133454157 130058.6608036264 140272.73155751597 132820.7141664271 157499.36513299352 142766.60292972514 160741.95774672483 0.6773508373384654 0.6571829568201493 0.6382608032871339 0.8868096005098335 0.809114574855154 0.872657851900364 0.8262977260467848 0.9798273415405295 0.8881726024183256 1.0 17.294387032772853 -5.4594679309597405 0.31273695625004067 0.990291656569201 0.4563343483432222 0.7702824206459232 0.05865107354439173 2.2512983474784054 0.24847983381709582 0.06758924619661963 0.44323573091883256 3.47161909964795e-06 5.4594679309597405 -0.5339573082259789 NSPFQIPPPSPDS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 NSPFQIPPPSPDSK 14 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 NS(0.002)PFQIPPPS(0.074)PDS(0.924)K 67.32600000000001 0.034578 5981300.0 39344.0 34563.0 28627.0 31459.0 34564.0 24734.0 24962.0 28212.0 30462.0 27930.0 True False 38782.947345194036 34482.971497044404 26273.398563415612 33772.599804147605 32531.01347543854 23676.184477770097 26254.410219995974 29522.832512969548 27031.04878091922 32757.663285614337 1.1839350996145603 1.0526688425968327 0.8020535022396937 1.0309831781859418 0.9930810141065425 0.7227678076832663 0.8014738411309609 0.9012496482291709 0.8251824480041596 1.0 14.999544827905305 -5.027807449886911 3.536521112221244 0.8817377350151002 1.171915293300939 0.5088580446120183 0.09563940584598962 0.18837154477939014 4.813531131409984 0.02588280378463064 0.10434164512232522 9.379777794110197e-06 5.027807449886911 0.2901775582858387 NSPGS(ph)QVASNPR ddPTM_PC-9_AZD4547_30min_R2 1 NSPGSQVASNPR 12 0 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 NS(0.279)PGS(0.661)QVAS(0.059)NPR 125.84 0.0018086999999999999 0.0 3512.0 3696.4 4160.4 3814.2 3232.4 4027.8 4446.0 4764.6 4235.3 4324.2 True False 4628.742945861983 4891.189012958279 4105.230377642932 2934.8951188025676 2783.6370552854128 3775.941029273384 4841.685386956745 4028.340549615894 4459.169311463679 4172.811074184041 1.1092625243684429 1.1721568328886567 0.9838045156275559 0.7033376461637344 0.6670891650252175 0.9048914417990368 1.1602934570680261 0.9653781295151501 1.0686247788813763 1.0 12.026803888103588 -9.709158999147473 15.803781635570868 0.9999995637515341 0.9635725488077526 0.0012563937966243444 0.16551396487032058 0.0 0.0 0.18112874519670716 0.043930173428330076 1.9536240853408814e-10 9.709158999147473 -0.03642701494378153 NSPGS(ph)QVASNPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSPGSQVASNPR 12 0 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 NS(0.099)PGS(0.901)QVASNPR 165.78 0.00084116 12590000.0 15092.0 14621.0 14659.0 16802.0 20530.0 11422.0 19490.0 14272.0 11945.0 13412.0 True False 17646.77751941275 16072.476253177276 15008.526154567084 15860.638412818975 16507.293875838124 10823.01021271817 17643.76610461946 13897.375122433968 12119.67302728018 15843.48943066641 1.113818871571052 1.0144530548975936 0.9472992815280209 1.0010823993178783 1.0418976165620981 0.6831203605797421 1.1136287988723281 0.8771663075391982 0.764962357586551 1.0 13.951602494632581 -1.5228788933245327 0.40200155288317935 0.8987048696340043 4.3664470213013145 0.21129072059608 0.11973315541982242 116.35578947530676 1.538488535587991 0.08432045518161965 320.07159090536027 0.029999989773471035 1.5228788933245327 3.46774215166731 NSPLDCGSAS(ph)PNK ddPTM_PC-9_AZD4547_30min_R2 2 NSPLDCGSASPNK 13 0 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 NSPLDCGS(0.007)AS(0.993)PNK;NSPLDCGSAS(1)PNK 154.13 0.00016030000000000002 24746000.0 135990.0 146529.0 105445.0 90280.0 111476.0 134152.0 138466.0 127460.0 147373.0 129554.0 True False 179231.99123228106 193891.63371923045 104046.73040346084 69467.34081209582 95999.4816158263 125763.45423285245 150789.2057558148 107763.98573942033 155162.8359120574 125018.3538931684 1.4336454260583185 1.5509053485451916 0.8322516427657624 0.5556571387226675 0.7678831037709909 1.0059599276144746 1.206136547635784 0.8619853196236098 1.241120452158955 1.0 16.931780386339128 -5.259552856823918 24.984047895912497 0.921807294512937 1.4922754374510772 0.5721302174813943 0.19293321428962915 118.87034799780406 1574222.7719127506 0.054243728395004825 0.12931378691622755 5.501069643837728e-06 5.259552856823918 0.5704681429381402 NSPLDCGSAS(ph)PNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSPLDCGSASPNK 13 0 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 NSPLDCGS(0.283)AS(0.717)PNK;NSPLDCGSAS(1)PNK 129.29 9.4483e-05 22795900.0 48423.0 84741.0 56809.0 60893.0 61676.0 39999.0 64799.0 44404.0 42406.0 41045.0 True False 56620.05750215502 93153.52644624122 58163.542009332225 57481.36262776966 49591.03054487053 37901.38202578483 58660.76961586641 43238.442049927 43026.10752572986 48486.133587958764 1.1677577342693348 1.9212405599892033 1.1995912584742947 1.1855216816472411 1.0227878957373941 0.7816952852515633 1.2098463060464457 0.891769230711871 0.8873899472243159 1.0 15.565284593566712 -5.720673297082273 1.8847190043568056 0.970216447734377 1.5403666268288951 0.5086543138611288 0.21110523661857805 0.24931912498155148 1.7994873532892477 0.06132991043801146 0.12984607053382471 1.9025089255232642e-06 5.720673297082273 0.5701501790945182 NSPLDCGSAS(ph)PNK ddPTM_PC-9_Lapatinib_30min_R1 2 NSPLDCGSASPNK 13 0 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 NSPLDCGS(0.005)AS(0.995)PNK;NSPLDCGSAS(1)PNK 172.42 0.00020822 31519000.0 48521.0 98554.0 83078.0 93686.0 115530.0 98411.0 112939.0 106332.0 83422.0 91911.0 True False 47829.081642338344 98325.80426813982 76247.64753035399 100575.98096733443 108734.75254071904 94202.19093724567 118786.428805229 111272.57290405086 74026.13588739549 107797.69388629058 0.44369299488716724 0.912132724952891 0.7073216947552062 0.9330067957986753 1.0086927523274933 0.8738794638465457 1.1019384972236028 1.032235188829046 0.6867135392106002 1.0 16.717966789313877 -4.434954479965635 1.0021204711266896 0.9480437409941825 1.9184444524877634e-25 0.5204410336447887 0.13208597335582922 2.9037355127234474 1.47280341683341 0.04202241055206665 3.4937586187681955 3.673207987517876e-05 4.434954479965635 -0.9480437409941825 NSPLEPDT(ph)STPLKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSPLEPDTSTPLKK 14 1 A0A3B3ITI3;A0A3B3IS53;A0A3F2YNX6;Q92794 A0A3B3ITI3 KAT6A Histone acetyltransferase KAT6A 1 NSPLEPDT(0.333)S(0.333)T(0.333)PLKK 80.361 0.0099222 4239200.0 18839.0 16732.0 20901.0 19953.0 23960.0 21218.0 21378.0 20548.0 20117.0 13810.0 True False 22028.07061278935 18393.04238206429 21399.359107483902 18835.098098498795 19265.20999829914 20105.290727845757 19352.921076683153 20008.636772405636 20411.17306737509 16313.643680100155 1.3502851383017405 1.1274637807923098 1.3117461388216691 1.154561081990186 1.1809262465257464 1.2324218379472613 1.1863027939178539 1.2264971066404213 1.2511719311531377 1.0 13.993791425984211 -10.983218195535654 3.0359017621550355 0.9949394635038317 1.2201190344313928 0.5181122715502111 0.0648517666756603 22048595.64306741 25819107.38717898 942376.0536763117 0.015244275413304026 1.0393978268257278e-11 10.983218195535654 0.22517957092756113 NSPLEPDTST(ph)PLKK ddPTM_PC-9_Lapatinib_30min_R1 1 NSPLEPDTSTPLKK 14 1 A0A3B3ITI3;A0A3B3IS53;A0A3F2YNX6;Q92794 A0A3B3ITI3 KAT6A Histone acetyltransferase KAT6A 1 NS(0.001)PLEPDT(0.03)S(0.122)T(0.847)PLKK 65.949 0.032049 4127000.0 26791.0 20633.0 21998.0 25628.0 21651.0 20124.0 15195.0 19022.0 22017.0 15427.0 True False 26408.955427132332 20585.225556187743 20189.409354735628 27512.768612501815 20377.530747503773 19263.343431335237 15981.722750293993 19905.831563225103 19537.21361071166 18093.53639481462 1.4595795344187557 1.1377115621292924 1.1158354516324216 1.5205854738483644 1.1262326116271952 1.0646533110495675 0.8832835329457295 1.100162573466283 1.0797896654581456 1.0 14.14318679086075 -6.502202964950362 10.754966222371976 1.0308921279577399 1.2876369767886342 0.5139572774794035 0.12918807662126885 0.5526232942747995 284.0877533503144 0.0412587596179868 0.04530942747469499 3.1462775762927546e-07 6.502202964950362 0.2567448488308943 NSPMAQT(ph)PPCHLPNIPGVTSPGTLIEDSK ddPTM_PC-9_AZD4547_30min_R2 1 NSPMAQTPPCHLPNIPGVTSPGTLIEDSK 29 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 1 NS(0.298)PMAQT(0.7)PPCHLPNIPGVT(0.001)SPGTLIEDSK 68.207 0.00014584 12688000.0 27013.0 35516.0 23516.0 31337.0 29166.0 43591.0 42248.0 35688.0 43889.0 37239.0 True False 35602.572094695264 46995.85244676613 23204.162474918554 24112.738801823707 25116.80434180618 40865.247879004935 46007.99015477924 30173.239628655523 46208.88293883069 35935.273944669425 0.9907416359066462 1.30779168454725 0.6457210402972486 0.6710047303090213 0.6989456760641158 1.1371903812929416 1.2803016397097478 0.8396551999329163 1.2858920460709395 1.0 15.133113063719428 -6.783672543543668 24.983127221831587 1.1093172542922745 0.8648406318874631 0.24273305053182137 0.21703059204753491 387.61320053734636 435553.0582234935 0.08165528817408307 0.0720676380161416 1.6456120410392243e-07 6.783672543543668 -0.24447662240481138 NSPMAQT(ph)PPCHLPNIPGVTSPGTLIEDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSPMAQTPPCHLPNIPGVTSPGTLIEDSK 29 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 1 NS(0.055)PMAQT(0.945)PPCHLPNIPGVTSPGTLIEDSK;NS(0.139)PMAQT(0.851)PPCHLPNIPGVT(0.003)S(0.003)PGT(0.003)LIEDSK 66.738 0.00018117 17996800.0 45986.0 60502.0 44044.0 57873.0 106238.0 84371.0 119928.0 72355.0 90731.0 80255.0 True False 53770.52153509906 66508.23871621175 45094.175997800165 54630.56343679752 85421.42653586414 79946.43623334318 108567.5516364703 70455.75791645938 92057.76922881203 94804.59620176947 0.5671720959673838 0.7015296871753399 0.475653900806958 0.57624382810016 0.901026215586263 0.8432759532374975 1.145171816410774 0.7431681663039915 0.9710264366601862 1.0 16.532669383364556 -6.283659856587583 4.947445010268204 0.9296929997538299 0.5798064252510347 0.7122988257853677 0.11022551392565134 0.10606346173721798 7.420042999660483 0.03351552440774479 0.03976895416410068 5.204034216851649e-07 6.283659856587583 -0.34988657450279526 NSPMAQT(ph)PPCHLPNIPGVTSPGTLIEDSK ddPTM_PC-9_Lapatinib_30min_R1 1 NSPMAQTPPCHLPNIPGVTSPGTLIEDSK 29 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 1 NS(0.132)PMAQT(0.868)PPCHLPNIPGVTSPGTLIEDSK 53.525 0.0044902 6044700.0 15714.0 14243.0 13111.0 20491.0 36441.0 31566.0 28202.0 40143.0 30994.0 30156.0 True False 15489.915478405337 14210.021208587303 12033.064189923582 21997.97649597217 34297.61202576252 30215.99576393998 29662.161566554216 42008.19032922642 27503.12933871086 35368.42441965577 0.43795887808326905 0.4017713947328164 0.3402205325051541 0.6219665381460119 0.9697240572215552 0.854321227471689 0.838662226357747 1.1877314587381123 0.777618166203247 1.0 15.110174331339804 -6.062856674223361 2.893816882466209 0.9392974221985396 0.39529228843226605 0.836391472282368 0.10886210387209536 0.09870968497227005 1.6301252987043475 0.03292574568248672 0.04681993096882379 8.65253422420763e-07 6.062856674223361 -0.5440051337662736 down NSPNNIS(ph)GISNPPGTPR ddPTM_PC-9_Lapatinib_30min_R1 2 NSPNNISGISNPPGTPR 17 0 Q9NW25;A0A087WVT6;Q9BWW4-2;Q9BWW4-3;Q9BWW4 Q9NW25 SSBP3 Single-stranded DNA-binding protein 3 1 NS(0.092)PNNIS(0.534)GIS(0.339)NPPGT(0.035)PR;NS(0.014)PNNIS(0.985)GISNPPGTPR 171.87 1.0385e-05 8406500.0 14213.7 22873.7 18630.2 17840.2 25404.8 24032.7 23074.5 22452.4 22529.9 16977.5 True False 14011.010031526657 22820.737353005945 17098.496870651677 19152.22782116258 23910.539611758515 23004.87744395995 24269.184705604384 23495.62047051599 19992.345411635215 19912.038253903225 0.7036451945736982 1.146077416184782 0.8587014876440372 0.9618416546286163 1.2008082400640974 1.1553250928216983 1.218819710777075 1.1799706374062584 1.0040330957940102 1.0 14.281353286609374 -6.163092659149679 5.295686773178024 1.1411081262441294 0.9253609917455637 0.40529700100048727 0.1236040060146268 0.22422074346429424 9.620174438414532 0.03511115556957092 0.04571857260174162 6.869218657676984e-07 6.163092659149679 -0.21574713449856564 NSPNNISGIS(ph)NPPGTPR ddPTM_PC-9_AZD4547_30min_R2 1 NSPNNISGISNPPGTPR 17 0 Q9NW25;A0A087WVT6;Q9BWW4-2;Q9BWW4-3;Q9BWW4 Q9NW25 SSBP3 Single-stranded DNA-binding protein 3 1 NS(0.186)PNNIS(0.297)GIS(0.516)NPPGT(0.001)PR 85.176 0.021524 0.0 4158.5 2915.0 3923.5 5364.7 4852.1 4000.4 5529.1 5230.0 4664.9 4601.1 True False 5480.816497826613 3857.2167440681174 3871.4718264306425 4127.951298788771 4178.469668342515 3750.2543556048563 6021.179188714022 4421.823673443969 4911.477090417896 4440.016889465843 1.2344134345142062 0.86873920529887 0.871949797221695 0.9297152244133434 0.9410931922930607 0.8446486689054085 1.356116280323069 0.9959024444107323 1.1061843260260147 1.0 12.116349449143385 -7.218884331336004 24.999955271722133 1.114209915789366 0.9401443715610546 0.25609621701285645 0.1382737689910086 633.3026280131418 372048.6617728524 0.051188197754118155 0.03964992786894627 6.041095046296775e-08 7.218884331336004 -0.17406554422831133 NSPNNISGISNPPGT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 NSPNNISGISNPPGTPR 17 0 Q9NW25;A0A087WVT6;Q9BWW4-2;Q9BWW4-3;Q9BWW4 Q9NW25 SSBP3 Single-stranded DNA-binding protein 3 1 NSPNNISGISNPPGT(1)PR;NSPNNISGISNPPGT(1)PR 329.64 9.149699999999994e-168 27561000.0 23557.0 28767.0 27061.0 40169.0 30927.0 33427.0 27054.4 35955.0 37763.0 33480.0 True False 31047.635983960925 38065.37018065438 26702.1534586567 30908.657654863466 26633.319888878817 31336.80440576033 29462.18918868255 30398.98091370516 39759.07508530754 32307.875390518904 0.9609928108448812 1.1782071622024728 0.8264905425038483 0.9566911250355369 0.8243599917032816 0.9699432112752439 0.9119197357474194 0.9409155057786953 1.2306310645538538 1.0 14.979598259699472 -8.233944094406958 24.56336145515159 1.1153155289157035 0.9458723818013476 0.2906447600865113 0.1056856257942198 630.3928463414934 563173.4601775738 0.07049061997133362 0.02662752745624536 5.835202144706645e-09 8.233944094406958 -0.16944314711435593 NSPNNISGISNPPGT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NSPNNISGISNPPGTPR 17 0 Q9NW25;A0A087WVT6;Q9BWW4-2;Q9BWW4-3;Q9BWW4 Q9NW25 SSBP3 Single-stranded DNA-binding protein 3 1 NS(0.026)PNNIS(0.025)GIS(0.005)NPPGT(0.944)PR;NSPNNISGISNPPGT(1)PR;NSPNNISGISNPPGT(1)PR 257.88 1.9720999999999996e-57 9127000.0 26952.499999999996 27255.699999999997 27342.9 29456.2 38130.0 30560.8 31758.7 28621.699999999997 30578.8 31458.0 True False 31515.025913859787 29961.465769353916 27994.858434525715 27805.864612288915 30658.70021849528 28958.137848786333 28750.28602292343 27870.4107021979 31025.957100593972 37161.08637860903 0.8480652474143148 0.8062591460351004 0.753337998499429 0.7482521993300701 0.8250216343552135 0.7792597222199472 0.7736664566263302 0.7499891262124375 0.8349044692744341 1.0 15.18150505807631 -8.629122175499713 4.856537193647583 0.9999908235471551 0.7848295840171344 0.8091080547780896 0.03128222456171497 0.3546670783660445 15.721040659443753 0.031260801169396654 0.00813588910316105 2.3489719163217097e-09 8.629122175499713 -0.21516123953002064 NSPNNISGISNPPGT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 NSPNNISGISNPPGTPR 17 0 Q9NW25;A0A087WVT6;Q9BWW4-2;Q9BWW4-3;Q9BWW4 Q9NW25 SSBP3 Single-stranded DNA-binding protein 3 1 NSPNNISGISNPPGT(1)PR;NSPNNISGISNPPGT(1)PR 248.23 4.3553999999999995e-47 26914000.0 23718.0 23948.0 19007.3 15785.6 22931.0 21968.0 26314.0 21946.0 23574.6 23373.0 True False 23379.77697065151 23892.54987736073 17444.59316429977 16946.525683217904 21582.243664080583 21028.479849909174 27676.410164609144 22965.691277811897 20919.38029645652 27412.991907435164 0.8528721363066636 0.8715776066340429 0.6363622483530633 0.61819321803475 0.787299822542423 0.767099042706304 1.009609248711832 0.8377666821396086 0.7631191942526566 1.0 14.742572174858713 -7.077138319378843 10.666136136183212 0.8892089402626594 0.7489497365355661 0.33354465057695815 0.10119181690850423 0.9016671464669913 121.78218537608386 0.041142175109722845 0.03187690969534475 8.372625781074973e-08 7.077138319378843 -0.14025920372709333 NSPQS(ph)SPTSTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NSPQSSPTSTPK 12 0 Q9Y6Y0 Q9Y6Y0 IVNS1ABP Influenza virus NS1A-binding protein 1 NSPQS(0.358)S(0.358)PT(0.128)S(0.128)T(0.028)PK;NSPQS(0.493)S(0.493)PT(0.01)S(0.002)T(0.001)PK;NSPQS(0.868)S(0.012)PT(0.097)S(0.023)TPK 158.11 0.00045695 6650400.0 31527.2 33149.4 35737.9 47116.0 49753.0 48846.0 53810.0 58592.0 46054.0 38668.0 True False 36864.132269416215 36440.25335524759 36590.02707274048 44476.243272132975 40004.2568048989 46284.429771531395 48712.727249336756 57054.02208335559 46727.4526243919 45678.20230428044 0.8070399098425493 0.7977602339186807 0.8010391220959165 0.9736863761813404 0.8757843957696678 1.013271701526532 1.0664326701134637 1.249042633142529 1.0229704819187495 1.0 15.479218253154453 -6.5815178590734265 0.9434255001078384 1.109611198420179 0.80487489559329 0.6818636814246827 0.07682871831893959 0.30110197407653677 0.5835561089152578 0.04197480493268006 0.04668533409969901 2.621091251809589e-07 6.5815178590734265 -0.3047363028268891 NSPQS(ph)SPTSTPK ddPTM_PC-9_Lapatinib_30min_R1 2 NSPQSSPTSTPK 12 0 Q9Y6Y0 Q9Y6Y0 IVNS1ABP Influenza virus NS1A-binding protein 1 NSPQS(0.589)S(0.036)PT(0.305)S(0.066)T(0.003)PK;NSPQS(0.652)S(0.146)PT(0.146)S(0.043)T(0.013)PK 104.17 0.0019420000000000001 7379400.0 25614.0 33793.0 35582.0 38493.0 51870.0 43181.0 48253.0 40010.0 45681.0 40321.0 True False 25248.739662967677 33714.75438473572 32656.585310492013 41323.90362888372 48819.10858034369 41334.249289827385 50751.304236257696 41869.01066368603 40535.92473774444 47290.43112564465 0.5339080034158494 0.7129297319189143 0.6905537660193375 0.8738322456627933 1.0323253017219811 0.8740510142529162 1.07318336983264 0.8853590391774057 0.8571697016262265 1.0 15.52926067380857 -5.718819149553881 1.9201923642477705 0.9522830230257178 0.6202375738747672 0.7650736753350773 0.07694490531328574 0.16053962718505627 1.2030245770856365 0.023292309516635613 0.04896914170001846 1.9106487320389683e-06 5.718819149553881 -0.3320454491509506 NSPQSS(ph)PTSTPK ddPTM_PC-9_AZD4547_30min_R2 1 NSPQSSPTSTPK 12 0 Q9Y6Y0 Q9Y6Y0 IVNS1ABP Influenza virus NS1A-binding protein 1 NSPQS(0.069)S(0.927)PT(0.004)STPK 217.12 1.0217e-73 0.0 20957.0 17049.0 23509.0 31294.0 26125.0 23580.0 23513.0 23456.0 24466.0 28530.0 True False 27620.890067320484 22559.755838633726 23197.255299492273 24079.651787480354 22497.99470032527 22105.538872403402 25605.6114492834 19831.414165258444 25759.222811671058 27531.17338385614 1.0032587308289937 0.8194258749560751 0.8425814249201158 0.8746322378544277 0.8171825583546596 0.8029275964447542 0.9300588497364277 0.7203257881077921 0.9356383926148194 1.0 14.748778478730847 -11.010692458817518 5.269885101516541 1.000291327724607 0.8542714321126007 0.22688118294641002 0.07634145086911275 0.00024285007973072505 2.3602852910437252e-05 0.06869721790982805 0.016628488823431955 9.756803111459408e-12 11.010692458817518 -0.14601989561200635 NSPS(ph)AASTSSNDSK ddPTM_PC-9_Lapatinib_30min_R1 1 NSPSAASTSSNDSK 14 0 D6RA28;A0A590UJ84;B1AKN3;Q9P2R6-2;Q9P2R6 D6RA28 RERE Arginine-glutamic acid dipeptide repeats protein 1 NS(0.212)PS(0.787)AASTSSNDSK 181.86 2.5663e-05 6210900.0 7814.7 24691.0 22532.0 21462.0 33738.0 26991.0 37222.0 37421.0 23661.0 24843.0 True False 7703.260944959538 24633.829506510516 20679.50593603524 23040.387075133196 31753.597171460075 25836.657849094077 39149.17303135526 39159.7162720769 20996.049018624184 29137.07944878328 0.2643799958914968 0.8454460767013898 0.7097315972379924 0.7907582884425065 1.0898002741584334 0.8867277825325413 1.3436203549559966 1.343982204562103 0.720595523498871 1.0 14.830568655856542 -4.857178083419728 0.5901147694266443 1.108426668507525 3.2605524913303193e-15 0.5372870400033631 0.20715521790477112 2.7784980778480466 0.7816311212696399 0.1102081019393613 2.083960760964542 1.389382794880013e-05 4.857178083419728 -1.1084266685075217 NSPS(ph)NLSSSSDTGSVGGTYR ddPTM_PC-9_AZD4547_30min_R2 2 NSPSNLSSSSDTGSVGGTYR 20 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 NS(0.027)PS(0.973)NLSSSSDTGSVGGTYR;NS(0.142)PS(0.858)NLSSSSDTGSVGGTYR 311.54 8.079699999999999e-140 9528500.0 12234.4 13609.400000000001 13892.2 15966.8 16976.5 19180.9 19619.8 18382.7 20357.4 17866.6 True False 16124.684708671368 18008.372403677742 13707.980350997768 12285.900944600922 14619.606010720452 17981.515290826228 21365.92419141114 15542.076107422268 21433.450603544192 17241.095772169792 0.9352470934416761 1.0445027764851507 0.7950759355518978 0.7125939735473519 0.847951093359107 1.0429450383224252 1.239243982734529 0.901455238854943 1.2431605790475109 1.0 14.073563848572611 -6.837680417294138 4.794701896302372 1.0937973733754125 0.864336719920987 0.4369842926396277 0.1246908867715433 0.20864198895058952 8.78279725607341 0.04571129323051732 0.040658518444082324 1.4531805709543248e-07 6.837680417294138 -0.22946065345442546 NSPS(ph)NLSSSSDTGSVGGTYR ddPTM_PC-9_Lapatinib_30min_R1 1 NSPSNLSSSSDTGSVGGTYR 20 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 NS(0.073)PS(0.902)NLS(0.024)S(0.001)SSDTGSVGGTYR 154.07 2.3528000000000002e-05 5055700.0 8905.3 8850.3 9471.2 10603.0 13189.0 14166.0 13228.0 12282.0 9533.2 9252.1 True False 8778.308788967985 8829.807674110813 8692.514495889263 11382.77999057112 12413.248950571675 13560.153202558884 13912.881114898915 12852.666557645392 8459.47062695355 10851.313157351682 0.8089628104614 0.8137086771040871 0.8010564592360097 1.0489771906416112 1.1439397951723282 1.249632464378008 1.2821380152938489 1.184434212824999 0.7795803608545132 1.0 13.405582018621528 -5.852716145897659 3.4210923942139977 1.1299247599825732 0.8051693124956211 0.49280005611088584 0.1345907739103187 0.19320512650593166 4.445059395413253 0.040644755776550405 0.06509677482714417 1.4037308808084857e-06 5.852716145897659 -0.3247554474869522 NSPSNLS(ph)SSSDTGSVGGTYR ddPTM_PC-9_Lapatinib_30min_R1 1 NSPSNLSSSSDTGSVGGTYR 20 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 NSPS(0.004)NLS(0.677)S(0.2)S(0.059)S(0.059)DTGSVGGTYR 150.9 8.405700000000001e-05 8706500.0 19602.0 32547.0 25594.0 23549.0 33691.0 28884.0 30758.0 32016.0 26855.0 23856.0 True False 19322.47188543345 32471.639421181728 23489.76011569706 25280.872017161124 31709.36161905453 27648.6986518926 32350.498739950137 33503.580240154275 23830.3071043131 27979.477813878122 0.6905944426114091 1.1605520173459223 0.8395353291420573 0.9035505303326833 1.1333078419114149 0.9881777935890764 1.1562223911092415 1.1974340787566857 0.851706642376757 1.0 14.772081417021436 -6.247080086259374 23.97729457680226 1.0661190242792336 0.9130559989799898 0.21868966810689072 0.14231475758446185 733.8043943095838 1225312.14917073 0.04027963976995516 0.051708926420744865 5.661348810673745e-07 6.247080086259374 -0.15306302529924376 NSPT(ph)FKSFEEKVENLK ddPTM_PC-9_Lapatinib_30min_R1 1 NSPTFKSFEEKVENLK 16 2 H0YC42;P55327-2;P55327;P55327-3;P55327-4;P55327-7;P55327-5;P55327-6;E5RK35 H0YC42 TPD52 Tumor protein D52 1 NS(0.015)PT(0.889)FKS(0.095)FEEKVENLK 84.493 0.041138 4478600.0 32630.0 8319.4 16907.0 17147.0 9788.1 10737.0 6356.6 8200.5 14868.0 24086.0 True False 32164.690216390853 8300.136940442417 15516.971722907316 18408.04758071517 9212.383202145014 10277.803539169465 6685.713644917324 8581.525167397087 13193.409273019082 28249.233007422357 1.1386040183087351 0.29381813439896204 0.5492882485988311 0.6516299956136345 0.32611091422285704 0.36382593242333405 0.2366688555105437 0.3037790500415473 0.46703601720983273 1.0 14.785924077115867 -10.958591665995863 2.937769610145837 1.0118154391799072 0.46227660412911786 0.27394295768274324 0.25169413445803784 57842843.91164301 67722482.02047613 5667297.748428408 0.062284903939506205 1.1000396367933591e-11 10.958591665995863 -0.5495388350507894 NSPTFKS(ph)FEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSPTFKSFEEK 11 1 H0YC42;P55327-2;P55327;P55327-3;P55327-4;P55327-7;P55327-5;P55327-6;E5RK35 H0YC42 TPD52 Tumor protein D52 1 NSPTFKS(1)FEEK 98.654 0.023586000000000003 7639700.0 25703.0 19596.0 13903.0 21423.0 25821.0 20043.0 17763.0 29137.0 18442.0 14380.0 True False 30054.010242609744 21541.361374547698 14234.500247421116 20222.73876430311 20761.560407599416 18991.909796315027 16080.3600470167 28372.184623203357 18711.67936116375 16986.980167982638 1.7692379661015956 1.268110115013217 0.8379653185355779 1.1904846278927956 1.2222043119077266 1.118027430920966 0.9466285289085843 1.6702312207722332 1.101530653248884 1.0 14.052141782165458 -4.790665543214781 4.1056362378571345 1.1518572824063544 1.814844399597052 0.44505672547698794 0.2107688928909505 0.20113524042316203 6.488121383446338 0.0529839707108364 0.3833454912259485 1.6193266256342212e-05 4.790665543214781 0.6629871171906976 NSPTFKS(ph)FEEK ddPTM_PC-9_Lapatinib_30min_R1 1 NSPTFKSFEEK 11 1 H0YC42;P55327-2;P55327;P55327-3;P55327-4;P55327-7;P55327-5;P55327-6;E5RK35 H0YC42 TPD52 Tumor protein D52 1 NSPTFKS(1)FEEK 119.87 0.0044535 20428000.0 46063.0 31197.0 30125.0 42056.0 23141.0 31684.0 18357.0 25840.0 29906.0 61631.0 True False 45406.13317308038 31124.765263237976 27648.23878586283 45148.93853470329 21779.891876956488 30328.9491790114 19307.435638509156 27040.620733557815 26537.671355858794 72283.83623185444 0.6281644077029569 0.43059094378172674 0.38249545440808597 0.6246062866653279 0.3013106804001972 0.4195813443233644 0.2671058516675772 0.3740894526796214 0.3671314741893019 1.0 16.141385454177616 -10.512350127778877 4.536572382069936 1.0000141080811626 0.41720610900547345 0.6994997131334473 0.11368210736772007 77031336.57928559 171079786.7068528 18112.033893611948 0.028590931626862076 3.073617867948065e-11 10.512350127778877 -0.5828079990756891 NSPTFKS(ph)FEEKVENLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSPTFKSFEEKVENLK 16 2 H0YC42;P55327-2;P55327;P55327-3;P55327-4;P55327-7;P55327-5;P55327-6;E5RK35 H0YC42 TPD52 Tumor protein D52 1 NS(0.018)PT(0.392)FKS(0.59)FEEKVENLK 47.606 0.03574 6942300.0 38273.0 13190.0 16755.0 39784.0 43764.0 51755.0 26885.0 50847.0 32739.0 30133.0 True False 44751.86297379304 14499.41603032681 17154.502743691355 37555.03146146829 35188.75836250268 49040.87669052959 24338.258169455843 49512.32012684976 33217.74593889709 35595.87436730326 1.2572205001066092 0.4073341725142538 0.48192390406481195 1.05503888102169 0.9885628317315747 1.3777123771280724 0.6837381747760031 1.390956705149221 0.9331908972408721 1.0 15.119422419203346 -5.809454336049051 11.802559228130484 1.0722230247446862 0.684805737539639 0.23108986378336827 0.2869636262921428 0.9291444743631121 226.2215856098221 0.07765644649120425 0.11534599776883157 1.5507638334914352e-06 5.809454336049051 -0.3874172872050472 NSPTPATS(ph)TESLSPLHNVALR ddPTM_PC-9_AZD4547_30min_R2 2 NSPTPATSTESLSPLHNVALR 21 0 G5EA48;Q7Z6B7-2;Q7Z6B7 G5EA48 SRGAP1 SLIT-ROBO Rho GTPase-activating protein 1 1 NS(0.006)PT(0.014)PAT(0.112)S(0.403)T(0.403)ES(0.06)LS(0.002)PLHNVALR;NSPTPAT(0.022)S(0.627)T(0.141)ES(0.209)LSPLHNVALR 95.5 0.00019641 7382000.0 10409.8 13497.4 26133.0 52107.0 33088.0 32101.0 19926.3 30047.0 21645.0 26035.8 True False 13719.899862709017 17860.17059395713 25786.459345001134 40094.53619512487 28494.302340454047 30093.71939537833 21699.702097641977 25403.92656137112 22789.110510856714 25124.294566680765 0.546080998465287 0.7108725200843194 1.026355557031182 1.595847242146941 1.134133428695049 1.1977936063242904 0.8636939851206649 1.0111299441243298 0.9070547413927826 1.0 14.61679546879867 -5.21554160192283 3.371893478462184 1.110554737899889 0.5895563745159998 0.4868136998449033 0.1935282976778929 0.21446386220695896 4.933774337890008 0.05533691035141184 0.1678593294514998 6.087772269999546e-06 5.21554160192283 -0.5209983633838892 NSPTPATSTES(ph)LSPLHNVALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSPTPATSTESLSPLHNVALR 21 0 G5EA48;Q7Z6B7-2;Q7Z6B7 G5EA48 SRGAP1 SLIT-ROBO Rho GTPase-activating protein 1 1 NS(0.003)PT(0.006)PAT(0.083)S(0.248)T(0.248)ES(0.411)LS(0.001)PLHNVALR;NSPTPATS(0.001)T(0.002)ES(0.756)LS(0.241)PLHNVALR 87.098 0.0002531 9439900.0 15472.0 18824.7 24264.3 26053.0 29615.0 31416.0 22636.4 21212.0 26246.7 19693.5 True False 18091.104014070643 20693.491807891816 24842.852934870174 24593.334874965618 23812.15334305632 29768.489655292782 20492.11631865613 20655.20747597178 26630.50833362198 23263.775656339774 0.777651241196547 0.8895156192005526 1.067877085038003 1.057151480407417 1.02357217052027 1.279606977605132 0.8808594366354149 0.8878699563259794 1.1447199597785287 1.0 14.505797641391798 -5.040690087892748 2.906177795053456 1.04117061224532 0.7816142250189612 0.38482963027333816 0.10979436629782845 0.30073847379792196 4.733373811575398 0.029686798969506815 0.13694997977534853 9.105628175618812e-06 5.040690087892748 -0.25955638722635876 NSPTPATSTESLS(ph)PLHNVALR ddPTM_PC-9_AZD4547_30min_R2 2 NSPTPATSTESLSPLHNVALR 21 0 G5EA48;Q7Z6B7-2;Q7Z6B7 G5EA48 SRGAP1 SLIT-ROBO Rho GTPase-activating protein 1 1 NSPTPATSTES(0.008)LS(0.992)PLHNVALR;NSPTPATSTES(0.029)LS(0.971)PLHNVALR 183.63 3.55e-15 15836900.0 33663.0 28067.0 29715.0 52894.0 45019.0 38397.0 34730.0 39755.0 35864.0 28729.0 True False 44367.1337661025 37139.10886990046 29320.959684563924 40700.10550415365 38768.888934505 35996.029520087926 37820.90271907507 33611.77822901814 37759.697822192895 27723.20645442705 1.6003608326849084 1.3396397321843632 1.0576323389130096 1.4680879562419575 1.3984273066766448 1.2984078728144308 1.3642326251563712 1.2124058695833417 1.3620249116661303 1.0 14.758806508178022 -13.498529031057087 0.21445543132965889 1.1653348130690815e-13 1.3861657595581252 0.3868173177724131 0.13406001636001574 103.33865521387139 1.530651862831324 45.141383851546685 0.2834109586462813 3.173006552430001e-14 13.498529031057087 1.3861657595580086 NSPTPATSTESLS(ph)PLHNVALR ddPTM_PC-9_Lapatinib_30min_R1 1 NSPTPATSTESLSPLHNVALR 21 0 G5EA48;Q7Z6B7-2;Q7Z6B7 G5EA48 SRGAP1 SLIT-ROBO Rho GTPase-activating protein 1 1 NSPTPATSTES(0.011)LS(0.989)PLHNVALR 93.179 0.00022708 4432600.0 20865.0 20807.0 15016.0 15801.0 20332.0 20126.0 19310.0 14395.0 18541.0 13310.0 True False 20567.46127382761 20758.82266987826 13781.442443436228 16963.05825059081 19136.111734249986 19265.257895997467 20309.777315444353 15063.844251531138 16452.717334614394 15610.615765539813 1.3175304281865647 1.3297888425197828 0.8828250371685238 1.086636075435057 1.2258396479460245 1.234112618319978 1.3010234586823837 0.9649743788316368 1.053944160930122 1.0 13.930239825537248 -1.5228797170096107 0.04967049364068503 0.6883752912078502 1.9740947852167385 0.18583273299904512 0.13870865140964908 1032.6862040682804 3.887900549806336 23.854843153240953 102.14969354680969 0.029999932875394934 1.5228797170096107 1.2857194940088883 NSPVTKT(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 1 NSPVTKTPPR 10 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 NS(0.001)PVT(0.104)KT(0.896)PPR 63.426 0.039794 14065000.0 138380.0 109620.0 136080.0 124070.0 109750.0 77729.0 72908.0 61033.0 64027.0 56755.0 True False 136406.67582421625 109366.18162503254 124892.02768399059 133194.52168538704 103294.72077680205 74404.71186514891 76682.81949841627 63868.81599192076 56815.60502579988 66565.02612871614 2.049224401421371 1.6429976518532754 1.8762409473480577 2.0009685180297248 1.5517866781432947 1.1177748465278636 1.1519986388968804 0.9594950938412952 0.8535353823182777 1.0 16.02247675078701 -6.675698810150039 2.071124454548546 0.9922143970915673 1.8767361622068557 0.9187131968108091 0.12365981279181959 0.08645083378892378 0.7607996263215093 0.048897827430808796 0.04764168131029819 2.1100910229338935e-07 6.675698810150039 0.8845217651152883 NSQEDS(ph)EDSEDKDVK ddPTM_PC-9_AZD4547_30min_R2 2 NSQEDSEDSEDKDVK 15 1 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 NSQEDS(1)EDSEDKDVK;NS(0.099)QEDS(0.9)EDS(0.001)EDKDVK 197.1 2.2020999999999998e-49 21147000.0 98271.0 91154.0 52679.4 82556.9 80916.0 86817.0 110803.0 69651.0 70672.0 96233.0 True False 129519.13383621968 120617.7478863758 51980.836735891535 63524.68219639025 69682.21011182835 81388.31926571012 120664.25234614676 58888.03837075452 74407.57764025248 92863.9119610456 1.394719768972797 1.2988656770885587 0.5597528215018163 0.6840620953275959 0.75036910076606 0.8764257023745754 1.2993664578416944 0.634132647733565 0.8012539647421363 1.0 16.502830436330882 -5.147776172550043 6.294033704363902 0.8244365015876989 1.3674628244261986 0.5263450903292166 0.19829707277595116 0.18381086347771491 8.858772219097443 0.05307567009399694 0.14498163108690598 7.1158015459029555e-06 5.147776172550043 0.5430263228384997 NSQEDS(ph)EDSEDKDVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSQEDSEDSEDKDVK 15 1 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 NS(0.007)QEDS(0.951)EDS(0.043)EDKDVK;NS(0.001)QEDS(0.988)EDS(0.011)EDKDVK 142.94 1.4943e-06 4022400.0 34066.0 34650.0 21958.0 35232.0 33654.0 24026.0 37518.0 33323.0 28312.0 27938.0 True False 39832.70096583056 38089.82300612764 22481.56199617873 33258.06526368516 27059.740287260418 22766.034264644277 33964.0234332023 32448.306558637 28726.009438958274 33002.93824291369 1.206944080937501 1.1541342993697294 0.6811988020795668 1.0077304335418151 0.8199191262332717 0.689818406381818 1.0291212007614194 0.9831944755889794 0.8704076354512542 1.0 15.010306852498628 -5.118958573669713 7.208056545567881 0.8851502518747175 1.1935201109141909 0.4956368693013188 0.11963185374016311 0.19204513363237669 10.399375659930495 0.03035034984318456 0.08191793624051479 7.6039880613655084e-06 5.118958573669713 0.30836985903947334 NSQEDS(ph)EDSEDKDVK ddPTM_PC-9_Lapatinib_30min_R1 3 NSQEDSEDSEDKDVK 15 1 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 NS(0.045)QEDS(0.842)EDS(0.113)EDKDVK;NS(0.007)QEDS(0.992)EDS(0.002)EDKDVK;NS(0.064)QEDS(0.929)EDS(0.007)EDKDVK 66.60600000000001 0.014875 58338000.0 85120.0 88280.0 62777.0 72905.0 72461.0 75718.0 78354.0 78934.0 55635.0 68512.0 True False 83906.17319090369 88075.59308390699 57615.717386227756 78266.67690395037 68198.98644380724 72479.7176472789 82410.78673093363 82601.56180273433 49368.800437477556 80354.20791349819 1.0442038490532968 1.0960918584216637 0.717021782459127 0.9740208874711943 0.848729496745508 0.9020027641278447 1.0255939156247966 1.027968092121018 0.6143897341458879 1.0 16.2940859551235 -5.212630817502436 24.990356365371664 0.896696109539697 1.0701480472648 0.23891843278532587 0.12890024452249502 559.4010104146665 286415.58719405247 0.03166871997791759 0.08378727010498552 6.128711562552495e-06 5.212630817502436 0.17345193772510292 NSQEDSEDSEDKDVK ddPTM_PC-9_AZD4547_30min_R2 1 NSQEDSEDSEDKDVK 15 1 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 0 107.69 0.0036067 0.0 12223.0 10447.0 8113.9 9424.8 10551.0 13290.0 9958.4 10454.0 8708.2 10653.0 False True 16109.659745806106 13823.788447780316 8006.3043844719205 7252.057971708468 9086.175773517003 12458.974199077235 10844.67830802295 8838.574509021659 9168.49767385735 10280.041712520846 1.5670811652626784 1.3447210463108599 0.7788202235327929 0.7054502476264891 0.883865652261922 1.2119575530420759 1.0549255159941997 0.859780023874464 0.8918735867277987 1.0 13.327558498003894 -5.0892620892066525 4.068677785604144 0.9255340051916285 1.5282589195843455 0.7175960393061563 0.13652016609342874 0.1241507806681443 3.621739416265597 0.039955523323857836 0.12829480013361233 8.14212772403891e-06 5.0892620892066525 0.6027249143927169 NSQEDSEDSEDKDVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSQEDSEDSEDKDVK 15 1 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 0 ; 75.998 0.018663 6956000.0 25080.0 24683.0 18854.8 26384.0 26115.0 20720.0 26120.0 23511.0 20117.6 21566.0 False True 29325.548647420608 27133.365115735913 19304.369939227203 24905.790018082123 20997.953218096096 19633.40672452465 23645.724507576204 22893.86116196364 20411.781841239983 25475.74508363793 1.151116426669509 1.065066596743528 0.7577548713825701 0.977627540875267 0.8242331342678672 0.7706705597841147 0.9281661607912275 0.8986532518205903 0.8012241359075959 1.0 14.636836720749184 -5.092810232067517 5.025865752034245 0.8675043140597122 1.132966500131434 0.599058841627576 0.07922311415532149 0.1253534076677043 5.011061723413961 0.01933070830267511 0.05627141932916305 8.075878341689889e-06 5.092810232067517 0.2654621860717218 NSQEDSEDSEDKDVK ddPTM_PC-9_Lapatinib_30min_R1 1 NSQEDSEDSEDKDVK 15 1 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 0 94.45 0.003928 7065000.0 13883.0 14246.0 11609.0 12583.0 13014.0 11134.0 13169.0 13791.0 13486.0 12882.0 False True 13685.025874169605 14213.01426227163 10654.552832035912 13508.395795657496 12248.542106508425 10657.824774621673 13850.826383588123 14431.780206520732 11967.064666124237 15108.636535813957 0.9057750407675912 0.9407211715352793 0.7051961841017252 0.8940843711235489 0.8106980452851665 0.7054127451777698 0.9167489303720898 0.9552007007588815 0.7920678108681186 1.0 13.883085851317922 -10.687658282697818 5.308719180203065 1.000005624587355 0.8472287396565867 0.217409321744659 0.08690063205611041 5.869036157176573e-06 9.233601942685334e-07 0.08536295393046285 0.02070279532355852 2.052776736367169e-11 10.687658282697818 -0.15277688493076824 NSQGEEVAQR ddPTM_PC-9_Lapatinib_30min_R1 1 NSQGEEVAQR 10 0 P20700 P20700 LMNB1 Lamin-B1 0 102.95 0.0139 2297200.0 5393.1 5187.7 7018.9 6461.7 5924.6 6060.7 6243.5 4503.5 5159.3 5240.2 False True 5316.1934050265845 5175.688199381335 6441.833135737521 6936.914973599303 5576.126676211763 5801.497989181747 6566.757880319876 4712.749050835044 4578.205304162452 6145.961587872401 0.8649896894111465 0.8421283025254062 1.048140806549939 1.128694814378219 0.9072830339868911 0.9439528552585862 1.0684671204710776 0.7668041824626007 0.7449127754388273 1.0 12.585423034808196 -7.772045002927828 24.994717004561384 0.8168938380489907 0.9723526845073658 0.2440916781292718 0.10684973577686509 282.96833877779875 666872.5497205354 0.05935460775886507 0.028980207648737506 1.690265772038437e-08 7.772045002927828 0.15545884645837504 NSQPNRYT(ph)NR ddPTM_PC-9_AZD4547_30min_R2 1 NSQPNRYTNR 10 1 P50750;P50750-2 P50750 CDK9 Cyclin-dependent kinase 9 1 NSQPNRY(0.427)T(0.573)NR 67.334 0.031620999999999996 86482000.0 7972.1 6845.3 9668.5 12740.0 10534.0 11618.0 8599.9 11038.0 9343.6 10030.0 True False 10507.061970018884 9057.909357862605 9540.28937271433 9802.98983103789 9071.535930075654 10891.52462339197 9365.274439786164 9332.330728006602 9837.483620662539 9678.852752894401 1.0855689448190862 0.9358453516253663 0.9856839045166137 1.0128255983754237 0.9372532222233535 1.125290868810348 0.967601706409423 0.9641980270043705 1.016389428769923 1.0 13.240620337761309 -4.734052930647015 24.39206365707583 0.9946286831903641 1.0855695901988367 0.22264113266992214 0.05137123126404266 3475.538230131216 3095305.1752452767 0.012500263800685715 1.0927369715343163 1.8447905673495263e-05 4.734052930647015 0.09094090700847257 NSQPNRYT(ph)NR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSQPNRYTNR 10 1 P50750;P50750-2 P50750 CDK9 Cyclin-dependent kinase 9 1 NSQPNRY(0.42)T(0.58)NR;NSQPNRY(0.127)T(0.873)NR 67.113 0.032036 130018000.0 20461.0 15859.4 18089.9 22987.0 24860.0 20806.7 18790.4 22263.0 20430.7 17196.4 True False 23924.643176829075 17433.8164208768 18521.23182232779 21699.112914859517 19988.861459003212 19715.560023898015 17010.437281284827 21678.61983959834 20729.46033641299 20313.9711933725 1.1777432855981684 0.8582180340279619 0.9117484536145449 1.068186653820742 0.9839957568476144 0.9705418914018289 0.8373762628370044 1.067177837028294 1.0204533687227066 1.0 14.310184680283642 NSQPNRYT(ph)NR ddPTM_PC-9_Lapatinib_30min_R1 1 NSQPNRYTNR 10 1 P50750;P50750-2 P50750 CDK9 Cyclin-dependent kinase 9 1 NSQPNRY(0.067)T(0.933)NR 65.809 0.034486 72258000.0 31877.0 19287.0 25785.0 25965.0 21190.0 19140.0 18444.0 20908.0 26732.0 19992.0 True False 31422.428134474136 19242.34213648975 23665.05683297837 27874.552716700862 19943.64586114289 18321.426817519212 19398.9400728149 21879.462008406612 23721.160659560523 23447.590562334484 1.3401133072048006 0.820653281425004 1.0092745678949724 1.1888024333501337 0.8505626967565603 0.781377803779558 0.82733191801706 0.933121974739406 1.0116673010175081 1.0 14.517152060824698 -4.751581733876219 24.989647302400783 0.9330889795941372 1.3401141310620892 0.5203652118035775 0.11640383149553196 356.9722524212956 904880.4989651885 0.031281618680000844 0.40841627668147823 1.7718145596637596e-05 4.751581733876219 0.40702515146795204 NSRDGDPLPS(ph)SLSCK ddPTM_PC-9_AZD4547_30min_R2 1 NSRDGDPLPSSLSCK 15 1 H3BP35;P53602 H3BP35 MVD Diphosphomevalonate decarboxylase 1 NS(0.011)RDGDPLPS(0.689)S(0.28)LS(0.021)CK 92.24700000000001 0.017622 16974000.0 55801.0 61206.0 70798.0 79797.0 80098.0 80730.0 67288.0 74931.0 79692.0 76687.0 True False 73544.55726709693 80989.64255143504 69859.17226140862 61401.03450136024 68977.77529212084 75681.94033796107 73276.50164587161 63352.135693084085 83904.35642555752 74002.21147170624 0.9938156685387127 1.0944219225448466 0.9440146567527694 0.8297189135332275 0.9321042428373048 1.0226983603982842 0.9901934035294054 0.856084357929032 1.1338087708046027 1.0 16.17528076423146 -8.274053650022914 24.941788810850202 1.0669043678174823 0.9600768665039856 0.23490385459427632 0.07862306522587456 1343.2836617998337 2656003.285618332 0.07734069822355683 0.020517170624317203 5.320425300018201e-09 8.274053650022914 -0.10682750131349672 NSRDGDPLPSS(ph)LSCK ddPTM_PC-9_Lapatinib_30min_R1 1 NSRDGDPLPSSLSCK 15 1 H3BP35;P53602 H3BP35 MVD Diphosphomevalonate decarboxylase 1 NS(0.232)RDGDPLPS(0.27)S(0.473)LS(0.025)CK 116.96 0.00065715 12144000.0 28443.0 45879.0 42751.0 44533.0 43317.0 46529.0 46971.0 42265.0 41828.0 32031.0 True False 28037.397604192603 45772.769994297334 39236.17780363229 47808.10537773304 40769.17922449869 44539.0631343966 49402.9285491319 44228.786195968285 37116.890171633175 37567.51567137532 0.7463202477760802 1.2184135462855223 1.0444176864622543 1.2725916133485657 1.085224255474601 1.1855738219158654 1.3150437995764148 1.1773146402030663 0.9880049161705549 1.0 15.19719809369009 -4.7559376161665945 24.98428281308112 1.1543724675229154 0.7463195966742348 0.5524028226693545 0.1066643158084432 125.78272867467923 571136.5097327806 0.025639794821429487 0.21673131592126899 1.7541324544966937e-05 4.7559376161665945 -0.4080528708486807 NSS(ph)EASSGDFLDLK ddPTM_PC-9_AZD4547_30min_R2 3 NSSEASSGDFLDLK 14 0 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 NS(0.085)S(0.915)EAS(0.001)SGDFLDLK;NS(0.327)S(0.644)EAS(0.027)S(0.003)GDFLDLK;NS(0.3)S(0.699)EAS(0.001)SGDFLDLK 175.19 2.4309e-05 116158000.0 220760.0 245466.0 204878.0 156049.0 184652.0 258416.0 266370.0 255305.0 258447.0 189938.0 True False 290957.0879067457 324808.0841507461 202161.18385509297 120074.31398301656 159016.25712552955 242257.20666882914 290076.4139729343 215853.47857526064 272107.9807899923 183288.3284326279 1.5874283452461848 1.7721154801743815 1.1029681245055505 0.6551116211807934 0.8675743757681759 1.3217274047969547 1.582623489741514 1.1776717067644755 1.4845897887601296 1.0 17.483755394256328 -6.968347772932565 24.98834471542058 1.344048954149871 1.1837545718902371 0.025032240970319863 0.33433537295475796 787.0071217691825 621312.9315616585 0.13250507895546984 0.11685751126741277 1.0756035503387744e-07 6.968347772932565 -0.16029438225963388 NSS(ph)EASSGDFLDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NSSEASSGDFLDLK 14 0 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 NS(0.028)S(0.774)EAS(0.142)S(0.056)GDFLDLK;NS(0.098)S(0.46)EAS(0.385)S(0.057)GDFLDLK;NS(0.469)S(0.48)EAS(0.047)S(0.004)GDFLDLK;NS(0.335)S(0.665)EASSGDFLDLK 154.39 0.00029377 107009700.0 93026.2 165173.0 100639.5 105199.0 105575.0 74058.4 116231.0 70967.5 69078.8 70057.7 True False 108773.69830879879 181570.2838496721 103039.12735742892 99305.04108975988 84888.33662647886 70174.64713163789 105220.75824043207 69104.67832128165 70088.94676574985 82758.60643355206 1.3143490809760623 2.193974641120343 1.2450563367105552 1.1999361198704228 1.025734244264212 0.8479437989084797 1.2714177144212204 0.8350150068895453 0.8469082526422814 1.0 16.33662173150993 -5.501524395368974 3.6876313497975146 1.0080086600422642 1.7595489162616542 0.5939472156226686 0.24311249495454207 0.13857577449838884 4.023520059906024 0.06341666662556707 0.13237621499435093 3.1511973648732374e-06 5.501524395368974 0.75154025621939 NSS(ph)EASSGDFLDLK ddPTM_PC-9_Lapatinib_30min_R1 2 NSSEASSGDFLDLK 14 0 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 NS(0.07)S(0.528)EAS(0.399)S(0.003)GDFLDLK;NS(0.162)S(0.82)EAS(0.016)S(0.001)GDFLDLK 159.64 3.3825e-05 61030000.0 45371.4 78829.0 63071.0 68521.8 77185.0 74234.0 87678.0 84498.0 67101.0 70452.0 True False 44724.39551590426 78646.47629373927 57885.54584110061 73561.12175402403 72645.13005154864 71059.18486790599 92217.53782825108 88424.08555511467 59543.378775144854 82629.53432861104 0.5412640392966384 0.9517961940940939 0.7005430480933661 0.8902521640927726 0.8791666398922784 0.8599731977831232 1.1160360345431612 1.070126877436573 0.720606490874626 1.0 16.334369916807113 -3.7984227966233046 0.44583118435093405 0.9693320269557114 6.67154943937448e-14 0.3758452847020526 0.13308804482161127 13.391653195275056 1.0550874037292464 0.08912630324183972 8.241184431371943 0.0001590659425992416 3.7984227966233046 -0.9693320269556447 NSS(ph)GPQSGWMK ddPTM_PC-9_AZD4547_30min_R2 1 NSSGPQSGWMK 11 0 F8VXG7;Q99590-2;Q99590 F8VXG7 SCAF11 Protein SCAF11 1 NS(0.43)S(0.57)GPQS(0.001)GWMK 69.258 0.030967 5749100.0 33472.0 32342.0 38713.0 56216.0 48575.0 49724.0 36536.0 43941.0 41419.0 43164.0 True False 44115.3997391493 42795.91901771904 38199.640325375156 43256.269728542036 41831.199715533025 46614.750419482 39787.63322038948 37150.928113728776 43608.32378143558 41652.84149809907 1.0591210143769572 1.0274429661580744 0.9170956638604953 1.0384950503440717 1.0042820180093137 1.1191253403830654 0.9552201431973203 0.8919182168021899 1.0469471520550586 1.0 15.3461272971183 NSS(ph)GPQSGWMK ddPTM_PC-9_Lapatinib_30min_R1 1 NSSGPQSGWMK 11 0 F8VXG7;Q99590-2;Q99590 F8VXG7 SCAF11 Protein SCAF11 1 NS(0.008)S(0.991)GPQS(0.001)GWMK 73.881 0.020812 5189800.0 41211.0 29153.0 30108.0 28686.0 38158.0 29542.0 29979.0 33134.0 30518.0 30094.0 True False 40623.323582828205 29085.49801965499 27632.63646024094 30795.664133690778 35913.62146151443 28278.557525765525 31531.165931626412 34673.52660161393 27080.741471213103 35295.7078022656 1.1509423131676264 0.8240519833912502 0.7828894270953599 0.8725045069563396 1.0175067649219707 0.8011896994441446 0.8933427857084213 0.9823723268523961 0.7672531068912242 1.0 15.10720513219929 -4.754093571622566 24.99921445058627 0.880410537948081 1.1509427883360854 0.4622678481780289 0.08688509109365378 234.5467561839016 798141.101842745 0.02111517238226476 0.21314555378671066 1.7615964578963232e-05 4.754093571622566 0.27053225038800444 NSS(ph)IVGR ddPTM_PC-9_AZD4547_30min_R2 1 NSSIVGR 7 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GUE9;Q96N67-7;A0A0U1RQT6 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 NS(0.451)S(0.549)IVGR 89.029 0.016874 7333000.0 26280.0 31276.0 36814.0 51466.0 50039.0 44263.0 37078.0 43669.0 49113.0 41552.0 True False 34636.49334204239 41385.35536448521 36325.822306159724 39601.30884177359 43091.94858601246 41495.22761277315 40377.870170396374 36920.95946379057 51709.01291382332 40097.27712744449 0.8638116057595223 1.0321238330709268 0.9059423708672876 0.9876308736851502 1.074685157524531 1.034863975448643 1.006997807907506 0.9207847043189898 1.2895891346804496 1.0 15.291216650940173 -3.429809911325911 0.3234954653951502 1.067509796531797 0.5465129986976865 0.23478901536808738 0.09748912773795623 27.882734268021608 1.1830392788774426 0.09256769778808036 6.754606060882794 0.0003716978839323437 3.429809911325911 -0.5209967978341105 NSS(ph)PAPPQPAPGK ddPTM_PC-9_AZD4547_30min_R2 4 NSSPAPPQPAPGK 13 0 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 NS(0.026)S(0.974)PAPPQPAPGK;NS(0.242)S(0.758)PAPPQPAPGK;NS(0.182)S(0.818)PAPPQPAPGK;NS(0.25)S(0.75)PAPPQPAPGK 212.03 1.004e-10 83432300.0 184446.0 208483.0 196801.0 168405.0 185322.0 230518.0 206995.0 228496.0 213368.0 184505.0 True False 243095.99128486906 275871.0526427288 194191.29015251104 129581.82908131373 159593.23919057145 216103.67301902815 225417.15399755124 193187.1935157269 224646.1968805945 178045.53610895106 1.365358529045692 1.549440995105407 1.090683284717006 0.7278016170089149 0.8963619233503943 1.2137550749196444 1.2660646198937118 1.0850437350898268 1.2617345078684097 1.0 17.441886739881063 -5.27559450395407 19.011417963535422 1.064762220344916 1.457399134556856 0.47768328639399893 0.16298505831688706 27.255960151847596 36609.00352517477 0.047281189818145455 0.10001601100873296 5.301582158483623e-06 5.27559450395407 0.3926369142119399 NSS(ph)PAPPQPAPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NSSPAPPQPAPGK 13 0 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 NS(0.126)S(0.874)PAPPQPAPGK;NS(0.05)S(0.95)PAPPQPAPGK;NS(0.009)S(0.991)PAPPQPAPGK;NS(0.179)S(0.821)PAPPQPAPGK 160.65 0.00017841 69391600.0 192303.0 261087.0 206710.0 232235.0 240069.0 164382.0 226092.0 173952.0 158170.0 157988.0 True False 224856.09974262083 287005.991896128 211638.75035204017 219223.62586602903 193029.2027997358 155761.51854202765 204674.9289956709 169385.94431737898 160482.93702175858 186629.97376767994 1.2048230796116672 1.537834390168204 1.1340019294836936 1.1746431799798793 1.0342883241253717 0.8346007631974602 1.09668840896079 0.9076031084279815 0.8598990493431156 1.0 17.509821183741565 -5.907608501087115 1.216041808855038 0.9415740967535772 1.3655728888347776 0.6542264167428611 0.11525836664797061 0.2784569338671126 0.8312280297081777 0.04088801492276083 0.08813028614740018 1.2370620924094594e-06 5.907608501087115 0.4239987920812004 NSS(ph)PAPPQPAPGK ddPTM_PC-9_Lapatinib_30min_R1 4 NSSPAPPQPAPGK 13 0 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 NS(0.253)S(0.747)PAPPQPAPGK;NS(0.008)S(0.992)PAPPQPAPGK;NS(0.019)S(0.981)PAPPQPAPGK;NS(0.032)S(0.968)PAPPQPAPGK 210.07 3.2261e-10 90891100.0 95967.0 162752.0 145144.0 143222.0 174162.0 170115.0 166626.0 176432.0 154224.0 135073.0 True False 94598.49298180755 162375.15774345337 133210.82059204267 153755.0236545863 163918.13357566626 162839.5780074335 175253.07897272048 184629.67481668244 136853.66906928268 158420.18807654097 0.5971366031714477 1.0249650610501835 0.8408702338346022 0.9705519575592177 1.0347048287587497 1.0278966335323203 1.1062547084469225 1.1654428457532087 0.863865083932116 1.0 17.27339666958958 -4.250970765568188 0.9703135912300381 1.0304110271925087 3.93757258946962e-53 0.5665792143783998 0.10086319345859168 3.7318663779370116 1.3722128117813557 0.03266773230291555 5.153598464304867 5.610857441173531e-05 4.250970765568188 -1.0304110271925087 NSS(ph)PEKHILENK ddPTM_PC-9_AZD4547_30min_R2 1 NSSPEKHILENK 12 1 E7EVA0;B5MEG9 E7EVA0 MAP4 Microtubule-associated protein 1 NS(0.012)S(0.988)PEKHILENK 56.46 0.036081 6472100.0 34384.0 24531.0 41181.0 62186.0 48624.0 42315.0 40165.0 44646.0 39979.0 47237.0 True False 45317.39676837087 32460.166020149216 40634.91303281261 47849.978464122614 41873.396911334596 39669.03636071878 43739.607190084964 37746.986563017104 42092.20832125385 45583.24700782381 0.9941678081991985 0.7121073673092622 0.891444021656424 1.0497272924833492 0.9186137377213943 0.8702547309521429 0.9595544429421097 0.8280890248239291 0.9234139971211185 1.0 15.476216074561588 NSS(ph)PGEASLLEK ddPTM_PC-9_AZD4547_30min_R2 3 NSSPGEASLLEK 12 0 Q76FK4-2;Q76FK4-4;Q76FK4 Q76FK4-2 NOL8 Nucleolar protein 8 1 NS(0.029)S(0.971)PGEASLLEK;NS(0.024)S(0.967)PGEAS(0.009)LLEK;NS(0.026)S(0.974)PGEASLLEK 186.29 0.000384 70115000.0 178435.0 197940.0 196819.0 162731.0 162889.0 206118.0 211515.0 217574.0 196069.0 195729.0 True False 235173.61832143553 261920.23407233073 194209.05146074988 125215.88211888734 140274.67401880506 193229.40887625242 230339.4252411512 183952.9376531354 206432.80705720306 188876.5872852709 1.2451178925963948 1.3867268454863486 1.0282325313694123 0.6629507866412621 0.7426789949722056 1.0230458504865254 1.2195234388328748 0.9739319218813549 1.0929507464332568 1.0 17.527084354030578 -5.35467454973559 5.1732034999627805 0.9553331025464166 1.3138417761931436 0.45143595044667595 0.1543365465906026 0.20287417263178587 8.561692131068156 0.04579056597439236 0.09892707570315598 4.419014740747579e-06 5.35467454973559 0.358508673646727 NSS(ph)PGEASLLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NSSPGEASLLEK 12 0 Q76FK4-2;Q76FK4-4;Q76FK4 Q76FK4-2 NOL8 Nucleolar protein 8 1 NS(0.053)S(0.943)PGEAS(0.003)LLEK;NS(0.008)S(0.992)PGEASLLEK;NS(0.014)S(0.986)PGEASLLEK;NS(0.234)S(0.766)PGEASLLEK 166.79 0.00058112 62540100.0 242371.0 313509.0 237308.0 272006.0 268530.0 206273.0 292258.0 188959.0 196293.0 195766.0 True False 283399.62325454416 344632.10161120066 242966.32271560145 256766.38567535087 215913.47415873362 195455.6807571369 264573.20647531404 183999.0264686102 199163.41377512793 231256.826117197 1.2254757103296146 1.4902569900209002 1.0506341663293013 1.1103083527801514 0.9336523283827841 0.8451888060509977 1.1440665813740472 0.7956479795989357 0.8612217728621568 1.0 17.81913642540666 -5.613224036511827 1.4471842791111373 0.9295671706997428 1.3635294603676478 0.6136568631961542 0.12356971567261449 0.280689842886252 1.1369440926384329 0.03861970427798559 0.11122905853567812 2.4365535659567073e-06 5.613224036511827 0.43396228966790495 NSS(ph)PGEASLLEK ddPTM_PC-9_Lapatinib_30min_R1 2 NSSPGEASLLEK 12 0 Q76FK4-2;Q76FK4-4;Q76FK4 Q76FK4-2 NOL8 Nucleolar protein 8 1 NS(0.115)S(0.885)PGEASLLEK;NS(0.029)S(0.971)PGEASLLEK 162.64 0.00049738 80855000.0 147355.0 227260.0 216250.0 202690.0 261560.0 221020.0 252090.0 235320.0 228010.0 184980.0 True False 145253.69067840237 226733.7934328126 198470.75974913946 217596.4987540182 246175.55504674563 211567.48982278418 265141.98671415646 246253.8262778956 202329.11274825645 216953.54652964347 0.6695151704217733 1.0450799125417054 0.9148076301302657 1.0029635478869061 1.1346924675099026 0.9751741476780912 1.2221140928799188 1.1350532416590327 0.9325918657919298 1.0 17.727026644453687 -4.296397854883647 1.2806062241605998 1.0594145080922988 1.7461636366324997e-54 0.5574990079118398 0.09623528889331999 3.2144674406755045 1.969978788475054 0.028302174932760833 6.059757522471022 5.0536149088555275e-05 4.296397854883647 -1.0594145080922988 NSS(ph)PINCSR ddPTM_PC-9_Lapatinib_30min_R1 2 NSSPINCSR 9 0 Q15723-2;Q15723-3;Q15723-1;Q15723;Q15723-4 Q15723-2 ELF2 ETS-related transcription factor Elf-2 1 NS(0.072)S(0.928)PINCSR;NS(0.485)S(0.515)PINCSR 82.029 0.016371 9911700.0 35461.0 40152.0 39202.0 32945.0 35629.0 34971.0 35121.0 34037.0 34723.0 32166.0 True False 34955.31963724902 40059.030510931545 35978.96288409609 35367.885201298275 33533.372269309126 33475.37185138265 36939.39353162718 35618.4832781775 30812.13009060003 37725.85024149913 0.9265614800855442 1.0618456642990612 0.9536952157149414 0.9374973651990207 0.888869887746673 0.8873324693040087 0.9791533734869458 0.9441399743191609 0.8167378572877363 1.0 15.203265795221796 -5.612452487828266 3.2406282089249325 0.9188873127785055 0.9966026788490395 0.19574230011187332 0.0573890793971645 0.34103866936671073 7.098799312177184 0.015617701415731527 0.03007425142237676 2.44088608837121e-06 5.612452487828266 0.07771536607053398 NSS(ph)PPPSPNK ddPTM_PC-9_AZD4547_30min_R2 2 NSSPPPSPNK 10 0 A0A0U1RQU3;E7ERY9;P20020-6;P20020;P20020-4;P20020-1 A0A0U1RQU3 ATP2B1 Calcium-transporting ATPase;Plasma membrane calcium-transporting ATPase 1 1 NS(0.064)S(0.924)PPPS(0.012)PNK;NS(0.005)S(0.994)PPPSPNK 110.93 0.0016683 5710300.0 76057.0 128209.0 89062.0 70252.0 70294.0 56120.0 83059.0 82006.0 64219.0 52865.0 True False 100241.54391612313 169650.05198635656 87880.979687923 54056.48678258031 60534.89146276225 52610.80752838334 90451.09009339649 69333.85701041041 67613.48523431298 51014.21244085365 1.9649728795155685 3.325544860327902 1.7226763970886156 1.059635819042662 1.1866279722135664 1.0312970643108683 1.7730566790238371 1.3591086423375982 1.325385260288095 1.0 15.63861161411318 -5.469308535407048 5.714811982186704 1.2794997718414682 2.6363885716300848 0.6886653764446364 0.37134010408885 0.1067593002368028 7.761345940066575 0.09338993618654041 0.19390895924470247 3.393840786235441e-06 5.469308535407048 1.3568887997886165 NSS(ph)PPPSPNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSSPPPSPNK 10 0 A0A0U1RQU3;E7ERY9;P20020-6;P20020;P20020-4;P20020-1 A0A0U1RQU3 ATP2B1 Calcium-transporting ATPase;Plasma membrane calcium-transporting ATPase 1 1 NS(0.047)S(0.951)PPPS(0.001)PNK 72.289 0.03095 2408600.0 58552.0 47386.0 29789.0 25362.0 49058.0 20375.0 23351.0 16155.0 19035.0 17084.0 True False 68463.69714528606 52090.16891683595 30499.282735411594 23941.04936471339 39445.43706579964 19306.499131862434 21139.024233400145 15730.948367637375 19313.350864317963 20181.193963130416 3.392450281701087 2.5811242393289975 1.511272464410757 1.1863049038848723 1.9545640925836008 0.9566579245575864 1.0474615264101625 0.7794855148994991 0.9569974353153763 1.0 14.30072390948094 -1.5228787457716755 0.47160084096397953 0.9370019809145815 68.40882315972341 0.882740201969064 0.2783184520448221 30.3707363797977 0.34765610411936404 0.17070886883467531 1999.2489801780525 0.02999999996605958 1.5228787457716755 67.47182117880882 up NSS(ph)PPPSPNK ddPTM_PC-9_Lapatinib_30min_R1 2 NSSPPPSPNK 10 0 A0A0U1RQU3;E7ERY9;P20020-6;P20020;P20020-4;P20020-1 A0A0U1RQU3 ATP2B1 Calcium-transporting ATPase;Plasma membrane calcium-transporting ATPase 1 1 NS(0.071)S(0.919)PPPS(0.009)PNK;NS(0.008)S(0.989)PPPS(0.003)PNK 122.55 0.00052963 6838300.0 151892.0 300820.0 83851.0 57473.0 103756.0 70227.0 60976.0 60970.0 107772.0 38687.0 True False 149725.99222641875 300123.4697723252 76957.09445422012 61699.75614430765 97653.27607214452 67223.55491713277 64133.038922140586 63802.88878192803 95633.58247052814 45373.99640281282 3.299819370046429 6.61443764194683 1.6960616334304068 1.3598043160351367 2.1521859173526714 1.4815436207194095 1.4134315688834684 1.4061553718017388 2.1076737790854945 1.0 15.469578113000598 -5.2823857718651315 24.06835253630681 1.595131337063888 4.9571280143817225 0.7356453874840969 0.8104155298433792 189.43760147831713 217672.250476253 0.19224402542166205 0.40097287995176 5.219323648379557e-06 5.2823857718651315 3.3619966773178342 NSS(ph)QDDLFPTSDTPR ddPTM_PC-9_AZD4547_30min_R2 2 NSSQDDLFPTSDTPR 15 0 Q9H6T3-3;Q9H6T3-2;Q9H6T3 Q9H6T3-3 RPAP3 RNA polymerase II-associated protein 3 1 NS(0.009)S(0.991)QDDLFPTSDTPR;NS(0.087)S(0.913)QDDLFPTSDTPR 181.86 1.0692999999999999e-05 3628100.0 15704.0 12576.099999999999 16233.8 26877.4 20895.4 19114.3 18061.6 21527.7 17015.1 18505.3 True False 20697.545336508138 16641.078385960565 16018.529205023502 20681.230681690544 17994.434390858438 17919.079799354553 19669.04741004453 18201.088622332652 17914.48344898488 17857.435079574945 1.1590435717266958 0.9318851398202405 0.897022956188442 1.1581299660075715 1.0076718358864534 1.0034520478167728 1.1014486303546291 1.0192442834721978 1.0031946564081415 1.0 14.1242372559932 -5.744773094041853 24.999283098502758 1.0421350850674334 0.9895741078514323 0.06286823595005642 0.08005396787007453 666.5553218952382 999818.4045417254 0.02146732778657234 0.03704722626450946 1.7998110172799668e-06 5.744773094041853 -0.05256097721600106 NSS(ph)QDDLFPTSDTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSSQDDLFPTSDTPR 15 0 Q9H6T3-3;Q9H6T3-2;Q9H6T3 Q9H6T3-3 RPAP3 RNA polymerase II-associated protein 3 1 NS(0.01)S(0.99)QDDLFPTSDTPR 161.26 0.00029889 1677000.0 11029.0 13450.0 12297.0 13533.0 15662.0 13800.0 15742.0 12405.0 11385.0 9611.8 True False 12895.991867320643 14785.227112046665 12590.207116632202 12774.789884577973 12593.143530607724 13076.303706488423 14250.803797789617 12079.381894183955 11551.484086696088 11354.343253033067 1.135776114913186 1.3021648881450816 1.1088450327824113 1.1251016108893366 1.1091036487067394 1.151656543675071 1.2550971447849106 1.0638556211480756 1.0173625923815857 1.0 13.47095664103295 -7.949446624652199 6.893775618574647 1.0187209537634527 1.1676192058692874 0.5520092389603377 0.06007750238154008 0.15506848615811597 16.476426632548616 0.03466652589241702 0.01635600307392671 1.1234490345145356e-08 7.949446624652199 0.14889825210583463 NSS(ph)SPVAATPASVNTTPDKPK ddPTM_PC-9_AZD4547_30min_R2 1 NSSSPVAATPASVNTTPDKPK 21 1 Q14469 Q14469 HES1 Transcription factor HES-1 1 NS(0.172)S(0.5)S(0.328)PVAATPASVNTTPDKPK 96.133 0.00015462 13941000.0 35982.0 31710.0 35496.0 46656.0 40368.0 43982.0 34780.0 40984.0 33722.0 40502.0 True False 47423.527527905986 41959.63737715267 35025.299847325616 35900.18002801439 34763.600002401145 41231.798587194506 37875.35262221226 34650.86451862862 35504.476075172555 39084.03730784935 1.2133733051775026 1.073574795936596 0.896153577263406 0.9185381680311839 0.8894577530100627 1.0549523904715394 0.9690747228563732 0.8865733149750524 0.9084137289993349 1.0 15.25429188224897 -4.968210416826778 2.8969005039923577 0.9392427120950084 1.2169129665846532 0.7329212659508323 0.052246362510390984 0.15480949782728542 2.3675488942682126 0.014372859220358747 0.08292484569929304 1.0759437897084816e-05 4.968210416826778 0.2776702544896448 NSS(ph)SPVAATPASVNTTPDKPK ddPTM_PC-9_Lapatinib_30min_R1 1 NSSSPVAATPASVNTTPDKPK 21 1 Q14469 Q14469 HES1 Transcription factor HES-1 1 NS(0.146)S(0.547)S(0.307)PVAATPASVNTTPDKPK 165.32 1.2255e-08 11989000.0 62043.0 48175.0 53128.0 50226.0 44578.0 54897.0 44499.0 47253.0 46971.0 36095.0 True False 61158.25544270728 48063.45374736315 48760.02092001067 53919.78758902431 41956.00968372008 52549.18328115731 46802.94048472077 49448.54688555752 41680.63135344224 42333.9726564357 1.444661381983717 1.1353400290926026 1.1517941232618543 1.2736765346029322 0.9910718756356036 1.2413005438356535 1.1055645749231544 1.1680582705256757 0.9845669739455898 1.0 15.36952825830297 -2.492676187171442 1.3740511139456215 1.1208608345261042 199.99963952735845 0.5051131430488419 0.09648234029319902 717.9843027445605 2.9153003492220697 0.02572340658428641 448455.986142038 0.003216057558628148 2.492676187171442 198.87877869283236 NSS(ph)SPVSPASVPGQR ddPTM_PC-9_AZD4547_30min_R2 2 NSSSPVSPASVPGQR 15 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 NS(0.001)S(0.587)S(0.413)PVSPASVPGQR;NS(0.004)S(0.494)S(0.494)PVS(0.007)PASVPGQR 173.51 7.642800000000001e-05 165739000.0 121550.0 126535.0 143700.0 193567.0 171590.0 132871.0 129060.0 164770.0 124465.0 141708.0 True False 160200.3716029394 167434.9642232106 141794.44410808798 148943.11873033838 147767.69035899796 124562.5553653568 140546.08997765146 139308.58253792775 131043.96579966627 136746.84605255796 1.1715105410282531 1.2244155463655655 1.0369119888409712 1.0891886945099476 1.0805930419938474 0.9108989271860926 1.0277830460794195 1.018733422812437 0.9582960746992306 1.0 17.061148033328088 -5.448570746749592 0.7407394565534141 0.9886651283875025 1.2448137818514773 0.6781857689382579 0.050588773141330194 0.7806843465109031 0.5927938510120107 0.023359248408045468 0.14406089406925385 3.5598299553614376e-06 5.448570746749592 0.25614865346397475 NSS(ph)SPVSPASVPGQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSSSPVSPASVPGQR 15 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 NSS(0.904)S(0.096)PVSPASVPGQR;NS(0.002)S(0.871)S(0.126)PVSPASVPGQR 215.93 9.988e-18 145318000.0 62498.0 62398.0 60562.0 71853.0 66178.0 49376.0 61928.0 52127.0 45519.0 47861.0 True False 73077.67700823325 68592.46106598413 62006.02776266399 67827.30936056921 53210.89596274795 46786.63563851972 56061.7315201064 50758.72148312185 46184.62926151244 56537.82043253248 1.2925449981829076 1.2132137486240144 1.0967176889434005 1.1996802996944085 0.9411557706976943 0.8275281091592661 0.991579284295294 0.8977834853696399 0.8168802565819694 1.0 15.786928647016625 -6.296273607591449 4.37401355099725 0.9038808265074604 1.1958542365145546 0.7987523207095168 0.07091001613664216 0.09369653601043007 4.23186666533407 0.022461342906156756 0.02655064998257932 5.055060904189622e-07 6.296273607591449 0.2919734100070942 NSS(ph)SPVSPASVPGQR ddPTM_PC-9_Lapatinib_30min_R1 3 NSSSPVSPASVPGQR 15 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 NS(0.004)S(0.498)S(0.498)PVSPASVPGQR;NS(0.002)S(0.853)S(0.116)PVS(0.027)PAS(0.002)VPGQR;NSS(0.855)S(0.145)PVSPASVPGQR 232.26 1.8460999999999999e-25 207987000.0 128872.0 135541.0 136760.0 129741.0 135030.0 132444.0 108157.0 117072.0 131099.0 105807.0 True False 127034.26164776956 135227.16314211427 125516.12070886674 139282.58594328814 127087.80087919427 126779.67886204354 113756.8402437345 122511.59251234801 116333.25008632819 124095.59897103463 1.0236806357445507 1.0897015225630835 1.01144699529726 1.1223813503313549 1.0241120711207337 1.0216291303903162 0.9166871443223921 0.987235595203853 0.9374486367843048 1.0 16.921092425882108 -6.933043003345348 2.4804060181840595 0.9597028737373743 1.0591054885089974 0.5675484734709083 0.03833194510579045 0.19378401901374923 2.41785752450099 0.014427768414644594 0.012004036398134228 1.1666940866205139e-07 6.933043003345348 0.09940261477162315 NSS(ph)YFVEWIPNNVK ddPTM_PC-9_AZD4547_30min_R2 3 NSSYFVEWIPNNVK 14 0 P04350;K7ESM5;Q9BUF5;P68371;A0A0B4J269;Q13509;Q13509-2;Q5JP53;P07437;Q5ST81;Q9BVA1;Q13885 P04350;P68371;A0A0B4J269;Q5JP53 TUBB4A;TUBB6;TUBB4B;TUBB3;TUBB;TUBB2B;TUBB2A Tubulin beta-4A chain;Tubulin beta-6 chain;Tubulin beta-4B chain;Tubulin beta-3 chain;Tubulin beta chain;Tubulin beta-2B chain;Tubulin beta-2A chain 1 NS(0.005)S(0.995)YFVEWIPNNVK;NS(0.009)S(0.991)YFVEWIPNNVK;NS(0.102)S(0.898)YFVEWIPNNVK 192.78 9.116599999999999e-37 3474800.0 82412.6 69973.0 85833.0 132622.0 115655.0 97061.0 70340.1 90109.7 83799.3 86892.0 True False 108618.09251143111 92590.40385340597 84694.79833771409 102048.04688947456 99598.29960061719 90991.76032630802 76600.23263317041 76185.31637991095 88228.7599183384 83849.93752786622 1.2953866838044283 1.1042393898341902 1.0100758668969443 1.2170318774007491 1.1878160263091102 1.085173859504288 0.9135395313528232 0.908591212182978 1.0522221306249269 1.0 16.355522088464042 -7.0664592627796425 4.245930677833336 0.9622865638437407 1.1533620138344312 0.5670844666640527 0.07963573273567133 0.17692029888680746 6.21908065465769 0.03211823181514907 0.02513447053549476 8.58105602039427e-08 7.0664592627796425 0.19107544999069048 NSS(ph)YFVEWIPNNVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSSYFVEWIPNNVK 14 0 P04350;K7ESM5;Q9BUF5;P68371;A0A0B4J269;Q13509;Q13509-2;Q5JP53;P07437;Q5ST81;Q9BVA1;Q13885 P04350;P68371;A0A0B4J269;Q5JP53 TUBB4A;TUBB6;TUBB4B;TUBB3;TUBB;TUBB2B;TUBB2A Tubulin beta-4A chain;Tubulin beta-6 chain;Tubulin beta-4B chain;Tubulin beta-3 chain;Tubulin beta chain;Tubulin beta-2B chain;Tubulin beta-2A chain 1 NS(0.003)S(0.997)YFVEWIPNNVK;NS(0.196)S(0.804)YFVEWIPNNVK 199.15 6.6021e-08 6141000.0 59141.0 56678.0 51800.0 85356.0 73231.0 77782.0 80639.0 79852.0 72533.0 51671.0 True False 69152.40321200568 62304.61726814731 53035.108452593944 80573.78004788565 58881.91124313203 73702.97499261463 73000.29014419761 77755.96961018743 73593.6579060453 61038.54327258906 1.1329301045600209 1.0207422052964823 0.8688790002039701 1.3200475589342808 0.9646677015238416 1.207482535477102 1.1959703857641093 1.2738831145255356 1.2056915837159967 1.0 15.897432911209282 -6.328653675079875 1.0560757469193973 1.190234539223295 1.0342708492404882 0.11481417489534873 0.13174039578923746 0.9096790293076087 2.1368953679331146 0.058630568824614794 0.08319085713028568 4.691873830091848e-07 6.328653675079875 -0.15596368998280674 NSS(ph)YFVEWIPNNVK ddPTM_PC-9_Lapatinib_30min_R1 1 NSSYFVEWIPNNVK 14 0 P04350;K7ESM5;Q9BUF5;P68371;A0A0B4J269;Q13509;Q13509-2;Q5JP53;P07437;Q5ST81;Q9BVA1;Q13885 P04350;P68371;A0A0B4J269;Q5JP53 TUBB4A;TUBB6;TUBB4B;TUBB3;TUBB;TUBB2B;TUBB2A Tubulin beta-4A chain;Tubulin beta-6 chain;Tubulin beta-4B chain;Tubulin beta-3 chain;Tubulin beta chain;Tubulin beta-2B chain;Tubulin beta-2A chain 1 NS(0.046)S(0.953)Y(0.001)FVEWIPNNVK 108.36 0.0006931 3211900.0 24528.0 22827.0 19304.0 17441.0 20265.0 19927.0 17970.0 18119.0 17971.0 16140.0 True False 24178.22622211569 22774.14548398671 17716.89963559489 18723.669321470414 19073.052542522928 19074.768662105795 18900.3986721147 18960.874886661535 15946.916736980478 18929.777494801845 1.2772588705152546 1.2030857462661955 0.9359275163408544 0.989111960064611 1.0075687655473196 1.007659422692304 0.9984480101419464 1.0016427764070777 0.8424249435240078 1.0 14.208369832903136 -5.161373287280242 4.167576828404708 0.9769316570888907 1.2602391027977817 0.8251000119624918 0.049548225628839926 0.08559551331693457 2.5546211760894177 0.01279742173471427 0.038203780070893235 6.896467798673092e-06 5.161373287280242 0.283307445708891 NSSCGGGISSSSS(ph)SR ddPTM_PC-9_AZD4547_30min_R2 2 NSSCGGGISSSSSSR 15 0 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 NSSCGGGISS(0.001)S(0.003)S(0.023)S(0.932)S(0.041)R;NSSCGGGISSS(0.003)S(0.021)S(0.971)S(0.005)R 148.33 5.6964e-05 3366000.0 7824.5 9743.7 13500.0 17084.9 13143.0 11282.2 13440.4 17518.2 13034.2 12669.2 True False 10312.528240289606 12893.16047656142 13320.981179256696 13146.240264073722 11318.321314693781 10576.72225047624 14636.569562495142 14811.164718188546 13723.16120215331 12225.655164204352 0.8435153864378399 1.0545987354781168 1.089592418593595 1.0752994491914643 0.9257844395802063 0.8651251903001449 1.197201243279766 1.211482290254214 1.122488816986555 1.0 13.577624159804405 -7.278607847743574 24.94683281660206 1.1504166193161325 0.9866828085705175 0.3854051504430065 0.09558274015028626 874.7774448555715 1271099.8630339429 0.041495344063484 0.028051970771923788 5.264924555210229e-08 7.278607847743574 -0.163733810745615 NSSCGGGISSSSS(ph)SR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSSCGGGISSSSSSR 15 0 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 NSSCGGGISS(0.001)S(0.017)S(0.066)S(0.458)S(0.458)R 112.67 0.0028822 0.0 6033.7 8552.9 4612.2 8655.6 6394.0 5631.7 6438.8 5486.7 5960.7 5796.0 True False 7055.08623899289 9401.975387853086 4722.172339865907 8170.654793833822 5141.141599713054 5336.363737958757 5828.870251124869 5342.679938639187 6047.863960963496 6846.768918889247 1.0304256390965563 1.3731988766138132 0.6896935468112725 1.19335921667988 0.750885806227429 0.7793988377841261 0.8513315288097218 0.7803213460146878 0.8833165004705084 1.0 12.741207606395728 -5.261329878094181 24.999999997492186 0.8621506103014859 1.2018122581116755 0.4252160706756394 0.15610209367669084 8.207024339199975 1873141.4973563661 0.038403671257984044 0.08930402000043973 5.478606670047366e-06 5.261329878094181 0.3396616478101896 NSSLGS(ph)PSNLCGS(ph)PPGSIR ddPTM_PC-9_Lapatinib_30min_R1 1 NSSLGSPSNLCGSPPGSIR 19 0 Q9C0B0 Q9C0B0 UNK RING finger protein unkempt homolog 2 NSS(0.003)LGS(0.58)PS(0.503)NLCGS(0.913)PPGS(0.001)IR 126.25 0.00036919 4025200.0 26906.0 28591.0 37404.0 29121.0 34024.0 35008.0 30864.0 30399.0 33393.0 29699.0 True False 26522.31550604389 28524.799296125817 34328.78750361539 31262.65548480823 32022.775213757726 33510.789447633884 32461.986901288168 31811.448517005578 29631.92869612092 34832.432578570006 0.7614258764793029 0.8189149360092398 0.9855409158169312 0.8975157108045904 0.9193378941170802 0.9620571107701149 0.9319471681475324 0.9132709421097672 0.8506993770613485 1.0 15.088143608905092 -5.0782980908958 4.6098314218544765 0.9284232186565391 0.7723487236980029 0.662786545606622 0.04138388628253424 0.11465783688085925 4.352753973396791 0.010359591145864959 0.031626735567488545 8.350296741099047e-06 5.0782980908958 -0.1560744949585362 NSSLGSPS(ph)NLCGSPPGSIR ddPTM_PC-9_AZD4547_30min_R2 1 NSSLGSPSNLCGSPPGSIR 19 0 Q9C0B0 Q9C0B0 UNK RING finger protein unkempt homolog 1 NSSLGS(0.005)PS(0.825)NLCGS(0.17)PPGSIR 107.91 0.00019358 55828000.0 37254.0 38961.0 37111.0 58666.0 57629.0 52554.0 42321.0 48065.0 44981.0 53775.0 True False 49099.997068662364 51554.38132611934 36618.88389210337 45141.460080664714 49628.20809894907 49267.79007210721 46087.4870133595 40637.6586738211 47358.60382946847 51892.3536178361 0.9461894411315742 0.9934870502462506 0.7056701293948818 0.8699058133518343 0.9563684172901186 0.9494229233644397 0.8881363784879206 0.783114579328955 0.9126316408433376 1.0 15.66323435145955 NSSLGSPSNLCGS(ph)PPGSIR ddPTM_PC-9_AZD4547_30min_R2 1 NSSLGSPSNLCGSPPGSIR 19 0 Q9C0B0 Q9C0B0 UNK RING finger protein unkempt homolog 1 NSSLGSPSNLCGS(1)PPGSIR 184.88 7.923300000000001e-11 45755000.0 55899.0 68186.0 62055.0 87094.0 77501.0 69853.0 78629.0 80795.0 63457.0 66805.0 True False 73673.71922857036 90225.79105009571 61232.11015398329 67015.82388888646 66741.32391463748 65485.08086742974 85626.8286754437 68309.98923439888 66811.20746996689 64466.17728385953 1.1428274846229503 1.399583391656847 0.9498331176729172 1.0395501441600956 1.035292097757867 1.0158052427877604 1.328244240362026 1.0596252502085575 1.0363761321814018 1.0 15.976254816625103 -5.26336776703635 24.999956019099635 1.066881988641116 1.2712054357731455 0.3660476589587296 0.1117061971305497 176.54090226906393 2288742.8009633915 0.029329461425186613 0.06638257501498607 5.452959008301326e-06 5.26336776703635 0.20432344713202943 NSSLGSPSNLCGS(ph)PPGSIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSSLGSPSNLCGSPPGSIR 19 0 Q9C0B0 Q9C0B0 UNK RING finger protein unkempt homolog 1 NSSLGSPSNLCGS(0.999)PPGSIR;NSSLGS(0.001)PS(0.001)NLCGS(0.991)PPGS(0.007)IR 124.94 2.7994e-05 65377000.0 151397.0 161766.0 154399.0 203872.0 199022.0 175076.0 200446.0 164756.0 142427.0 142981.0 True False 177025.52187294827 177825.05940575013 158080.45772146815 192449.71280194167 160025.06779138139 165894.7063563164 181458.3037766321 160431.32957341187 144509.7254295881 168902.32346302664 1.0480940595923764 1.0528277868520661 0.9359282600755493 1.1394142416523336 0.9474414828071414 0.9821931572932528 1.0743387068701515 0.9498467888662935 0.8555816312451252 1.0 17.365829648790026 -7.940654651631312 6.937018144595219 0.9195512588179916 1.022683528469348 0.2862176325525021 0.06577006212854485 0.2338959116207365 21.781775526751467 0.034846056731193654 0.016495631719411638 1.1464242087390719e-08 7.940654651631312 0.10313226965135647 NSSLGSPSNLCGS(ph)PPGSIR ddPTM_PC-9_Lapatinib_30min_R1 2 NSSLGSPSNLCGSPPGSIR 19 0 Q9C0B0 Q9C0B0 UNK RING finger protein unkempt homolog 1 NSSLGS(0.001)PS(0.004)NLCGS(0.994)PPGS(0.001)IR;NSS(0.005)LGS(0.024)PS(0.116)NLCGS(0.853)PPGS(0.002)IR 175.02 1.3125e-08 102002000.0 108664.0 103683.0 104819.0 106954.0 135683.0 119848.0 137331.0 123616.0 126670.0 97515.0 True False 107114.43143346318 103442.92838376471 96201.18643304083 114819.753948085 127702.39270304157 114722.38041933336 144441.32721425616 129359.65064239509 112403.09070576583 114370.33781942989 0.9365577952788556 0.9044559136223101 0.8411375560062184 1.0039294815178796 1.116569165902619 1.003078093556559 1.2629264717422006 1.131059443460162 0.9827993240977396 1.0 16.80335340916134 -5.991381589860478 3.986287687976465 1.0931111401634728 0.8959055332458997 0.5202979034897357 0.08055562646232406 0.16521946282574232 6.020023117009816 0.024117055853675306 0.03502652790676509 1.0200428362241757e-06 5.991381589860478 -0.19720560691757305 NSSLLS(ph)FDNEDENE ddPTM_PC-9_Lapatinib_30min_R1 1 NSSLLSFDNEDENE 14 0 Q96AT1 Q96AT1 KIAA1143 Uncharacterized protein KIAA1143 1 NS(0.021)S(0.021)LLS(0.959)FDNEDENE 125.36 3.526e-05 1205500.0 10080.0 7673.3 9827.9 9767.4 10402.0 9366.9 8348.6 9350.8 12640.0 19982.0 True False 9936.257351554397 7655.532945296147 9019.887998791088 10485.727179091227 9790.174811118854 8966.299522310377 8780.84965798647 9785.27230477369 11216.350094899191 23435.862075658624 0.4239766098416568 0.32665890081540777 0.3848754515482273 0.44742229431287284 0.4177433191709769 0.3825888500864287 0.3746757695381128 0.41753413094784536 0.4785977174080111 1.0 14.516430244108339 -9.068736052573536 1.3890164621331877 1.0001883310546793 0.3934144840721204 0.9709822783195472 0.0311036198927486 0.4630014400568542 1.0264132791367382 0.031669407317886186 0.009267432957094167 8.536187529337328e-10 9.068736052573536 -0.606773846982559 NSSNTSVGS(ph)PSNTIGR ddPTM_PC-9_AZD4547_30min_R2 2 NSSNTSVGSPSNTIGR 16 0 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 NSSNT(0.002)S(0.005)VGS(0.992)PSNTIGR;NSS(0.002)NT(0.004)S(0.026)VGS(0.859)PS(0.083)NT(0.026)IGR 169.62 3.3075e-05 112747000.0 27590.0 31632.0 34140.0 60630.0 51781.0 47904.0 43593.0 47668.0 44852.0 56833.0 True False 36363.04609234969 41856.42540252578 33687.281293320295 46652.69022416222 44592.10195512126 44908.55530719303 47472.692549169 40302.00590166866 47222.78515282723 54843.293968618855 0.6630354134665306 0.7632004275030578 0.6142461339502336 0.8506544163969569 0.8130821241451454 0.8188522617348541 0.865606150067002 0.734857500075202 0.8610493961184743 1.0 15.743027603647562 -7.548744155423489 0.043466838837499716 1.6407109814988199 8.368750772127977e-12 0.6153299783502864 0.06503756919773479 44.998246835342314 1.5714436781061618 28.089002970633604 30.38125917175992 2.8265446130228174e-08 7.548744155423489 -1.640710981490451 NSSNTSVGS(ph)PSNTIGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NSSNTSVGSPSNTIGR 16 0 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 NSSNT(0.014)S(0.006)VGS(0.954)PS(0.026)NT(0.001)IGR;NSSNTSVGS(0.972)PS(0.025)NT(0.003)IGR;NSSNT(0.001)S(0.026)VGS(0.915)PS(0.039)NT(0.018)IGR;NSSNT(0.017)S(0.05)VGS(0.841)PS(0.091)NTIGR 245.74 5.8193e-47 126701600.0 63515.4 70433.3 74649.2 114821.0 117023.0 99387.0 102765.0 83576.0 79727.1 77327.6 True False 74267.30273366753 77425.45254653638 76429.12003666756 108387.95162470477 94093.18320663445 94174.97075918599 93030.35524582975 81382.21855609164 80892.9580086456 91346.48175505515 0.8130286061023642 0.847601911523556 0.8366947316220851 1.186558579402611 1.0300690447930392 1.030964400048985 1.0184339173049914 0.8909179312928264 0.8855618350530391 1.0 16.47906154351682 -5.590400659402342 24.99998084646199 1.0046604765409377 0.8332690161621106 0.5037109944161071 0.07897645137518305 45.29706493565085 16770.5702539132 0.023193715489820105 0.04017269906734878 2.568025551554144e-06 5.590400659402342 -0.17139146037882713 NSSNTSVGS(ph)PSNTIGR ddPTM_PC-9_Lapatinib_30min_R1 4 NSSNTSVGSPSNTIGR 16 0 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 NS(0.001)S(0.002)NTSVGS(0.996)PS(0.002)NTIGR;NSSNT(0.061)S(0.007)VGS(0.92)PS(0.01)NTIGR;NSSNTSVGS(0.999)PS(0.001)NTIGR;NSSNT(0.011)S(0.019)VGS(0.955)PS(0.004)NT(0.011)IGR 208.4 3.7234e-17 139777400.0 88520.0 69255.6 70209.0 76052.0 69616.3 52314.2 45342.899999999994 49858.2 53279.6 44108.3 True False 87257.68856742026 69095.24291325145 64436.687034577386 81645.1177820347 65521.606104911865 50076.843616356455 47690.53349748639 52174.79398830769 47278.69038893917 51732.36088438465 1.686713830100085 1.3356290285624246 1.2455779309702357 1.578221376064806 1.2665496989658842 0.9679984203363912 0.9218704246664627 1.0085523470485296 0.9139093901900421 1.0 15.658779412159605 -6.635093950416685 3.3143757426770204 0.958157905124783 1.4372217399512084 0.7998322178583505 0.11785958154703054 0.11031316364660984 2.3925359573238785 0.04121463734634025 0.041066619376572855 2.3168933849186543e-07 6.635093950416685 0.47906383482642534 NSSNTSVGSPS(ph)NTIGR ddPTM_PC-9_AZD4547_30min_R2 1 NSSNTSVGSPSNTIGR 16 0 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 NSSNT(0.007)S(0.001)VGS(0.327)PS(0.663)NT(0.002)IGR 159.01 5.0752e-05 3580400.0 5051.1 3832.3 7908.7 15180.0 11364.0 8482.0 7782.6 9859.3 7648.0 9401.3 True False 6657.244730593237 5071.0160302889335 7803.82547054722 11680.48552866209 9786.304756918516 7951.619199140186 8475.236323106066 8335.771729175163 8052.257666298543 9072.163348533015 0.7338100599422878 0.5589643655511258 0.8601945501575556 1.2875082910131732 1.0787178736702288 0.8764854526595331 0.9342023503662472 0.9188295458241581 0.8875785583821755 1.0 13.14723090157328 -5.516370284441325 24.975740048607886 0.9963809351899483 0.6621852140737552 0.575646086065171 0.11976040532086527 207.9501342620488 797991.9658473085 0.03494613588875322 0.06346893017429357 3.045297427021019e-06 5.516370284441325 -0.3341957211161931 NSSNTSVGSPSNT(ph)IGR ddPTM_PC-9_AZD4547_30min_R2 1 NSSNTSVGSPSNTIGR 16 0 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 NSSNT(0.039)S(0.017)VGS(0.419)PS(0.06)NT(0.465)IGR 163.44 1.2700999999999999e-15 0.0 5270.3 3832.9 7070.2 12746.0 9240.1 8094.3 7212.2 7442.6 6182.9 9023.7 True False 6946.145770950003 5071.809968555296 6976.444528413386 9807.606623736965 7957.271610735899 7588.162141428955 7854.071828117286 6292.51718393386 6509.715471359475 8707.783009600513 0.7976939438306779 0.5824456079077212 0.8011734468718054 1.126303516397213 0.9138114261647128 0.8714229710435879 0.9019599844711343 0.7226313720721139 0.7475743784821438 1.0 13.088089741927101 -5.51941979035729 24.999999984715178 0.8918620611484465 0.690504681943187 0.3299818912126422 0.11844085936979788 159.69302429753947 1154198.3486621575 0.03370118207741191 0.059986983204671114 3.0239890180433096e-06 5.51941979035729 -0.20135737920525942 NSSQDDLFPT(ph)SDTPR ddPTM_PC-9_AZD4547_30min_R2 1 NSSQDDLFPTSDTPR 15 0 Q9H6T3-3;Q9H6T3-2;Q9H6T3 Q9H6T3-3 RPAP3 RNA polymerase II-associated protein 3 1 NS(0.001)SQDDLFPT(0.949)S(0.047)DT(0.003)PR 105.0 0.0026715 2429500.0 5841.2 5717.1 7028.7 13533.0 8725.2 9905.1 8347.6 11605.0 8721.9 10953.0 True False 7698.580095492313 7565.040771016063 6935.4948455290005 10413.175932765753 7513.856587914949 9285.732531172303 9090.520228556039 9811.713906370418 9182.921827888247 10569.538803833737 0.7283742685820802 0.7157399117804558 0.6561776227183524 0.9852062730484258 0.7108972990561855 0.8785371531825232 0.8600678229459515 0.9283010440163724 0.8688100775558398 1.0 13.367624806417806 -2.2583828752308337 0.12806925849410408 1.0571838293918294 5.568398648313011e-11 0.5072678575793057 0.08158866434113521 56.47360907010528 0.589688712645733 0.4734664129314992 10.463120373214512 0.005515909407457708 2.2583828752308337 -1.0571838293361455 NSSQDDLFPTSDT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 NSSQDDLFPTSDTPR 15 0 Q9H6T3-3;Q9H6T3-2;Q9H6T3 Q9H6T3-3 RPAP3 RNA polymerase II-associated protein 3 1 NSSQDDLFPT(0.003)S(0.024)DT(0.973)PR 85.176 0.014362 2017400.0 6094.7 7997.1 7183.0 10002.0 7047.5 6697.1 6927.8 11445.0 9159.0 10050.0 True False 8032.687822364759 10582.006183185984 7087.748726711176 7696.193429359573 6069.07627370497 6278.32927830249 7544.360779073084 9676.438229936175 9643.126041530903 9698.152558981925 0.828269897128531 1.0911362879505828 0.7308349382632542 0.7935731452514385 0.6257971543336991 0.6473737384640158 0.7779173129304807 0.9977609829383804 0.9943260825073267 1.0 13.243494233215419 -7.762252441577406 24.758494757105872 0.9970327168701126 0.7835931636899951 0.39846803185038293 0.11956839302931901 22.092764759179794 672648.992941823 0.06806688659483023 0.03571640512050393 1.728811164123465e-08 7.762252441577406 -0.21343955318011754 NSSQDDLFPTSDT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 NSSQDDLFPTSDTPR 15 0 Q9H6T3-3;Q9H6T3-2;Q9H6T3 Q9H6T3-3 RPAP3 RNA polymerase II-associated protein 3 1 NSSQDDLFPT(0.022)S(0.23)DT(0.748)PR;NSSQDDLFPT(0.095)S(0.355)DT(0.551)PR 193.27 1.0829999999999999e-10 1681000.0 29076.0 26974.0 32896.0 32164.0 31498.0 25101.8 23802.8 21430.3 31508.0 21228.0 True False 28661.37090811462 26911.54336027761 30191.417862232185 34529.44785595866 29645.349567450623 24028.25452915378 25035.192516005114 22426.029973156492 27959.237246050914 24897.23151546798 1.1511870663333825 1.080905053381465 1.212641567937988 1.386879012411739 1.1907086757430345 0.9650974452410771 1.0055412185267032 0.9007439224406859 1.1229857917608466 1.0 14.603697708149607 -6.735035998621924 7.824734828696326 0.9930240348957549 1.2088016039881913 0.574553660407708 0.08836294032826751 0.14908735670076398 34.80188064114641 0.031397279031989286 0.030804569591273256 1.8406194264034052e-07 6.735035998621924 0.2157775690924364 NSSQSGGKPGSS(ph)PITK ddPTM_PC-9_AZD4547_30min_R2 1 NSSQSGGKPGSSPITK 16 1 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 NSSQS(0.005)GGKPGS(0.128)S(0.546)PIT(0.321)K 108.18 0.0039753 11039000.0 27598.0 25532.0 27822.0 50183.0 37558.0 31714.0 33766.0 33733.0 28699.0 37201.0 True False 36373.589925939326 33784.71969452733 27453.062101428124 38614.08466962122 32343.719998270466 29730.91856655645 36771.10858659052 28520.339957224725 30215.970549830294 35898.604313103126 1.0132313114095868 0.9411151308240633 0.7647389815488636 1.0756430621322772 0.9009743029609897 0.8281914892079677 1.0243046851035633 0.7944693255613476 0.8417032118098627 1.0 15.13164013474802 -6.500399384512039 24.733770232395607 0.8896636429174453 0.9416660496190833 0.052983453731624275 0.09990907172550409 2245.598613679562 2470807.639476161 0.030868275120396665 0.0347118092259998 3.1593709131821497e-07 6.500399384512039 0.052002406701638026 NSSQSGGKPGSS(ph)PITK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSSQSGGKPGSSPITK 16 1 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 NSSQS(0.001)GGKPGS(0.156)S(0.487)PIT(0.355)K 52.03 0.039672000000000006 32818000.0 78874.0 66893.0 55314.0 78151.0 68925.0 62815.0 67202.0 73966.0 69024.0 56330.0 True False 92225.81036749033 73533.6949595641 56632.89553951315 73772.45283896044 55419.641032252424 59520.87082051238 60836.140059653 72024.47087345514 70033.34541942131 66542.18309196531 1.3859751225779395 1.1050688682386043 0.8510826201966213 1.1086569362625578 0.8328497572082829 0.8944832894684405 0.9142492360909437 1.082388156305497 1.0524654011220371 1.0 16.021981577965708 -4.847336784777154 3.066005419288304 0.9656570790926029 1.421896644970931 0.6621265527220057 0.0909463229146934 0.18949825695868608 2.8519773665366115 0.02369414468695058 0.1958494952542452 1.4212262333996843e-05 4.847336784777154 0.45623956587832803 NSSQSGGKPGSS(ph)PITK ddPTM_PC-9_Lapatinib_30min_R1 2 NSSQSGGKPGSSPITK 16 1 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 NSSQS(0.003)GGKPGS(0.255)S(0.733)PIT(0.01)K;NSSQSGGKPGS(0.261)S(0.721)PIT(0.018)K 72.428 0.0076858000000000004 109769000.0 181377.0 140423.0 148951.0 151206.0 156152.0 136209.0 123968.0 154856.0 139401.0 116373.0 True False 178790.5307195321 140097.85917106364 136704.82374748721 162326.19364842906 146967.446366644 130383.65858868723 130386.45645991738 162051.17508962148 123700.19142239257 136487.91799272454 1.3099366841324556 1.0264487965779618 1.0015891938125558 1.1893081529537421 1.0767798976498277 0.9552761922534221 0.9552966912929802 1.1872931866266696 0.9063087285790848 1.0 17.058413722846083 -6.54650149927075 9.367886630056224 1.0102692831703108 1.1172528002235904 0.24850303191544376 0.10594353136321781 0.49017879905098605 180.6411180662495 0.03457871544975304 0.03481977307504435 2.8411783766546415e-07 6.54650149927075 0.10698351705327958 NSSQSLMVPQSGS(ph)PEPESIR ddPTM_PC-9_AZD4547_30min_R2 4 NSSQSLMVPQSGSPEPESIR 20 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970;A0A075B6R8;B7ZB24;H0YGQ3 F5H1U9 MPDZ Multiple PDZ domain protein 1 NSSQSLMVPQS(0.028)GS(0.972)PEPESIR;NSSQSLMVPQS(0.234)GS(0.766)PEPES(0.001)IR;NSSQSLMVPQS(0.206)GS(0.794)PEPESIR;NSSQSLMVPQS(0.134)GS(0.864)PEPES(0.002)IR 199.7 1.9311e-59 19654200.0 57669.5 59348.9 69944.0 105959.0 85839.0 77815.0 64552.0 85314.0 71472.0 80665.0 True False 76007.20139988262 78532.27129400492 69016.49685940224 81531.78960023099 73921.73653899404 72949.21574877309 70297.00294620593 72130.6816206882 75249.86400702003 77840.9429025152 0.976442455162329 1.0088812951862043 0.8866349029948887 1.0474152362509026 0.9496510934042844 0.937157401088161 0.9030851930229443 0.9266419307256042 0.9667131614947145 1.0 16.248241565420578 -6.504208175501887 24.846945594616486 0.9398515844267287 0.9781690110282413 0.10382664800031127 0.04471314724395672 1406.0544400488527 1871192.2248453237 0.013553148794069938 0.01509627867096234 3.1317841693812597e-07 6.504208175501887 0.038317426601512605 NSSQSLMVPQSGS(ph)PEPESIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSSQSLMVPQSGSPEPESIR 20 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970;A0A075B6R8;B7ZB24;H0YGQ3 F5H1U9 MPDZ Multiple PDZ domain protein 1 NSSQSLMVPQS(0.226)GS(0.774)PEPESIR 175.6 2.2809000000000003e-09 5830800.0 20758.0 19953.0 20375.0 24398.0 27775.0 21887.0 22288.0 24597.0 20480.0 20382.0 True False 24271.919410811694 21933.801975216884 20860.81727261779 23031.059159383243 22332.6881345058 20739.207190138564 20176.719288853696 23951.354812675756 20779.481255646544 24077.095256176763 1.0080916801865851 0.9109820658116956 0.8664175246499528 0.9565547220018092 0.9275491041128207 0.8613666627754072 0.838004712535975 0.9947775908113854 0.8630393755789854 1.0 14.555373730439154 -11.186210589470853 2.555677616020892 1.0120147068391445 0.9128236081572457 0.17708589877074699 0.055500254857916896 20478391.462951448 17308221.855732277 1609883.8940418817 0.014488139834953983 6.513124959333804e-12 11.186210589470853 -0.09919109868189879 NSSS(ph)PVAATPASVNTTPDKPK ddPTM_PC-9_AZD4547_30min_R2 1 NSSSPVAATPASVNTTPDKPK 21 1 Q14469 Q14469 HES1 Transcription factor HES-1 1 NS(0.042)S(0.144)S(0.814)PVAAT(0.001)PASVNTTPDKPK 140.07 6.5504e-05 11973000.0 19267.0 18380.0 18671.0 28466.0 26743.0 21149.0 20441.0 23732.0 19603.0 23054.0 True False 25393.50522150421 24320.975559510123 18423.41034058532 21903.60349531588 23030.196067781762 19826.549686703103 22260.20940053594 20064.76470710751 20639.174559682328 22246.88647709148 1.1414408594952345 1.0932305329356724 0.8281343261025156 0.9845693921201472 1.0352098524661817 0.8912055944151692 1.000598866877762 0.9019133858470043 0.9277331720524272 1.0 14.441315819971383 -5.085744166788158 6.971688380984104 0.9473953780105848 1.12998116495121 0.5796917076567003 0.05890475041261983 0.14995426401824005 10.294884363357506 0.014629388453472872 0.039797569984938615 8.20834937527566e-06 5.085744166788158 0.1825857869406251 NSSS(ph)PVAATPASVNTTPDKPK ddPTM_PC-9_Lapatinib_30min_R1 1 NSSSPVAATPASVNTTPDKPK 21 1 Q14469 Q14469 HES1 Transcription factor HES-1 1 NS(0.186)S(0.186)S(0.628)PVAATPASVNTTPDKPK 166.75 1.0038e-08 12173000.0 41434.0 33286.0 38520.0 36466.0 37778.0 32899.0 36700.0 33341.0 33324.0 27298.0 True False 40843.14356193497 33208.928312085736 35353.034291499986 39147.831287009925 35555.9723144057 31491.98646131476 38600.14642552084 34890.1445773046 29570.700202723147 32016.422927701416 1.2756935293541634 1.037246677652816 1.1042156199439648 1.2227421962601024 1.110554180106166 0.9836197670310975 1.2056358236111075 1.089757736399614 0.9236103692626396 1.0 14.966524509616494 -8.139850201674042 4.891252563924454 0.964156553007775 1.1272810513235056 0.39449120130953663 0.08370111480107373 0.22888546800087295 7.924104154397401 0.059059171931113284 0.02109620347931496 7.2468587808265365e-09 8.139850201674042 0.16312449831573061 NSSS(ph)PVSLDAALPESSNVYRDPSAK ddPTM_PC-9_AZD4547_30min_R2 1 NSSSPVSLDAALPESSNVYRDPSAK 25 1 Q70EL1-7;Q70EL1;H7C296;R4GN32;H7C1E9;Q70EL1-6 Q70EL1-7 USP54 Inactive ubiquitin carboxyl-terminal hydrolase 54 1 NS(0.019)S(0.224)S(0.705)PVS(0.052)LDAALPESSNVYRDPSAK 92.865 1.8041e-06 5262500.0 14604.0 13825.0 20949.0 23038.0 20692.0 20506.0 19141.0 24445.0 18183.0 21272.0 True False 19247.768217929504 18293.66088738995 20671.202572166567 17726.945033551863 17819.27296991886 19223.756578350454 20844.511918969645 20667.586940217563 19144.116258669772 20527.27375469289 0.9376680239152133 0.8911880411400321 1.0070115895171305 0.8635800957006858 0.8680779134562409 0.9364982806816015 1.015454471356881 1.006835451565632 0.9326185487389963 1.0 14.325254414119433 -7.081021204502267 5.512266134804855 0.9885650768028329 0.9135316344755559 0.4029571184580626 0.0432781048650745 0.23971369028349862 12.286099460502827 0.01704327125118085 0.013240368205098453 8.298102508980626e-08 7.081021204502267 -0.07503344232727704 NSSS(ph)PVSLDAALPESSNVYRDPSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSSSPVSLDAALPESSNVYRDPSAK 25 1 Q70EL1-7;Q70EL1;H7C296;R4GN32;H7C1E9;Q70EL1-6 Q70EL1-7 USP54 Inactive ubiquitin carboxyl-terminal hydrolase 54 1 NS(0.027)S(0.102)S(0.652)PVS(0.219)LDAALPESSNVYRDPSAK 59.005 0.0019105999999999997 6235200.0 18064.0 13679.0 15768.0 15399.0 19018.0 13780.0 17391.0 13613.0 12632.0 17767.0 True False 21121.87841973708 15036.960718638384 16143.968920473004 14536.243954231595 15291.55942185531 13057.352541696408 15743.598580063468 13255.673174165748 12816.719102603873 20988.01645650539 1.0063780187855818 0.7164545896845611 0.769199364500644 0.6925973202067878 0.7285852597621525 0.6221337099080264 0.7501232244928808 0.6315829417056253 0.6106684321105169 1.0 14.357278205846802 NSSS(ph)PVSPASVPGQR ddPTM_PC-9_AZD4547_30min_R2 2 NSSSPVSPASVPGQR 15 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 NS(0.001)S(0.027)S(0.972)PVSPASVPGQR;NSS(0.027)S(0.973)PVSPASVPGQR 247.02 3.0293999999999996e-40 95991000.0 174181.0 180705.0 180432.0 262610.0 195593.0 210175.0 192665.0 204873.0 177194.0 200799.0 True False 229566.93481013237 239114.3573711249 178039.35378782544 202069.3217840548 168438.2881309368 197032.72402491033 209811.81175843911 173214.58536319074 186560.1130912795 193769.08812845915 1.1847448786977883 1.2340170441046001 0.918822271949767 1.042835695495935 0.8692732662253677 1.0168429130155556 1.0827929975050739 0.8939226944617615 0.9627960522144767 1.0 17.563978911233114 -5.256929825116709 24.98361386600767 0.9738401854101014 1.209380985643373 0.6856309455126329 0.06391286194912976 200.36461803073442 1110040.986156837 0.01620888129567188 0.03993742249330797 5.534395287648453e-06 5.256929825116709 0.23554080023327162 NSSS(ph)PVSPASVPGQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 NSSSPVSPASVPGQR 15 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 NSS(0.042)S(0.913)PVS(0.042)PAS(0.004)VPGQR;NSS(0.004)S(0.647)PVS(0.3)PAS(0.048)VPGQR;NSS(0.035)S(0.963)PVS(0.003)PASVPGQR;NS(0.001)S(0.018)S(0.845)PVS(0.135)PAS(0.001)VPGQR;NS(0.001)S(0.013)S(0.986)PVSPASVPGQR 171.15 1.6891e-06 141087900.0 106123.0 104002.0 101588.0 119478.0 138157.0 94586.0 102797.8 94788.2 85700.1 87917.4 True False 124087.52787520822 114326.63123472719 104010.24319463543 112784.03501290256 111086.12761832304 89625.7436508633 93060.04819237831 92300.11018639957 86953.30183383981 103856.12866624449 1.1948021697783482 1.1008173778759947 1.0014839232924444 1.0859641742987463 1.0696155252937756 0.8629798241265816 0.8960477285980799 0.8887305099058552 0.8372476708936054 1.0 16.664226828178457 -6.729650711992096 7.096083501064456 0.8899208443934378 1.0867611805782027 0.7270859896236277 0.059199171937914234 0.09961339536599824 16.017947503444 0.019871559054669335 0.019515552960424305 1.863585351244774e-07 6.729650711992096 0.19684033618476493 NSSS(ph)PVSPASVPGQR ddPTM_PC-9_Lapatinib_30min_R1 2 NSSSPVSPASVPGQR 15 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 NS(0.004)S(0.048)S(0.533)PVS(0.406)PAS(0.008)VPGQR;NS(0.002)S(0.043)S(0.954)PVS(0.001)PASVPGQR 114.54 0.00017411 71632000.0 81014.0 95904.0 108434.0 78037.0 92163.0 86141.0 73498.0 85324.0 84952.0 65511.8 True False 79858.72550385207 95681.94018032425 99518.9750873445 83776.10130380063 86742.15353942954 82456.95023447856 77303.36681152413 89288.46453057617 75383.81117578127 76835.4273410137 1.0393477106520181 1.2452841546083333 1.2952225103877653 1.0903316894690076 1.1289343541286945 1.0731631629835965 1.0060901525078219 1.1620741579830483 0.9811074628531731 1.0 16.229484042895166 -6.365402395525964 1.521208546770921 1.0515115797220274 1.1911978397501843 0.34742283685274233 0.08130970484006206 0.452288993409292 2.1000897380067953 0.031057963928820907 0.03897430111298978 4.3111943802445097e-07 6.365402395525964 0.13968626002815698 NSSS(ph)STSPVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSSSSTSPVSK 11 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 NS(0.001)S(0.005)S(0.277)S(0.277)T(0.163)S(0.277)PVSK 64.827 0.046218 1261800.0 19024.0 21018.0 20976.0 19349.0 30003.0 24482.0 21709.0 23877.0 24012.0 19796.0 True False 22244.387458872807 23104.52813687709 21476.147391923 18264.93826030439 24124.12752833763 23198.12082190214 19652.56636045067 23250.25404977269 24363.130073759028 23384.858094950225 0.9512303802979376 0.9880123301610425 0.9183783499871058 0.781058332111434 1.0316131673917255 0.9920146073886841 0.8403970757767603 0.9942439657050303 1.0418335649007018 1.0 14.5132870537058 -7.984187484027195 24.936766654529574 1.0199574785906314 0.930493937174929 0.23293275351192266 0.07015721861629076 328.068537059763 517372.6033855001 0.039465766904746145 0.018950844754970626 1.037080613617133e-08 7.984187484027195 -0.08946354141570234 NSSSPVAATPASVNT(ph)TPDKPK ddPTM_PC-9_Lapatinib_30min_R1 1 NSSSPVAATPASVNTTPDKPK 21 1 Q14469 Q14469 HES1 Transcription factor HES-1 1 NSSSPVAATPAS(0.001)VNT(0.959)T(0.04)PDKPK 134.15 3.2796e-05 12589000.0 31682.0 27084.0 18969.0 29384.0 25373.0 22078.0 18731.0 21402.0 25718.0 22448.0 True False 31230.20887023276 27021.288662035997 17409.442042457496 31544.997382150505 23880.610025237325 21133.775406331708 19700.79952851312 22396.415051842272 22821.368017453904 26328.106889920175 1.186192725546453 1.0263285839355663 0.6612492920682715 1.1981490926804022 0.9070386308094228 0.8027077485933051 0.7482801407212325 0.850665607879951 0.8668062657475445 1.0 14.684316168357892 -6.5170411464662825 24.380895964237503 0.8396706028844271 1.0005327916854878 0.20488151726621961 0.15019379100208174 317.6370851853022 1326628.9493885962 0.04889855605089001 0.05045676719359357 3.040596936024298e-07 6.5170411464662825 0.16086218880106073 NSSSPVS(ph)LDAALPESSNVYRDPSAK ddPTM_PC-9_AZD4547_30min_R2 1 NSSSPVSLDAALPESSNVYRDPSAK 25 1 Q70EL1-7;Q70EL1;H7C296;R4GN32;H7C1E9;Q70EL1-6 Q70EL1-7 USP54 Inactive ubiquitin carboxyl-terminal hydrolase 54 1 NS(0.001)S(0.012)S(0.228)PVS(0.757)LDAALPES(0.001)S(0.001)NVY(0.001)RDPSAK 59.943000000000005 0.0016416 3783000.0 8163.4 7502.8 8856.0 11378.0 10306.0 10178.0 13495.0 12616.0 11754.0 11954.0 True False 10759.191390731698 9927.933374749316 8738.563653592393 8754.977888347645 8875.189794509179 9541.568051031452 14696.028856720943 10666.48708683922 12375.292443733415 11535.494098514415 0.9327031247077061 0.8606422308367245 0.7575370052608131 0.7589599382201707 0.7693809834857581 0.8271486222909387 1.2739834749352916 0.9246666849071417 1.0728012461405665 1.0 13.49379217968737 -7.1184761751562675 9.835673792367103 1.0613758398484128 0.8106037679989084 0.6187465606761766 0.09612233191125127 0.258446158134928 20.085530608388527 0.03625767300959961 0.028085088760384888 7.612438987337862e-08 7.1184761751562675 -0.25077207184950434 NSSSPVS(ph)LDAALPESSNVYRDPSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSSSPVSLDAALPESSNVYRDPSAK 25 1 Q70EL1-7;Q70EL1;H7C296;R4GN32;H7C1E9;Q70EL1-6 Q70EL1-7 USP54 Inactive ubiquitin carboxyl-terminal hydrolase 54 1 NS(0.032)S(0.114)S(0.419)PVS(0.434)LDAALPESSNVYRDPSAK 77.657 5.9358e-05 7894700.0 56434.0 46554.0 47953.0 56879.0 68706.0 49066.0 58468.0 49981.0 42180.0 41728.0 True False 65987.16157769284 51175.573455332415 49096.381382765234 53692.25403420607 55243.55251014781 46492.89258424357 52929.48776833708 48669.05170924691 42796.80270327986 49292.95608133374 1.3386732471230482 1.0381924218724548 0.9960121138151229 1.0892480042303296 1.1207190012908852 0.9431954640239055 1.0737738609346748 0.9873429304775843 0.868213353499531 1.0 15.589093881069875 -4.761629080174641 4.897832857790147 1.0160589132595856 1.3605073295012629 0.6650164462579635 0.06949513400466859 0.1124995833338261 6.845236494046293 0.01777436677314068 0.13441133820935902 1.731294382270005e-05 4.761629080174641 0.3444484162416772 NSSSPVS(ph)LDAALPESSNVYRDPSAK ddPTM_PC-9_Lapatinib_30min_R1 1 NSSSPVSLDAALPESSNVYRDPSAK 25 1 Q70EL1-7;Q70EL1;H7C296;R4GN32;H7C1E9;Q70EL1-6 Q70EL1-7 USP54 Inactive ubiquitin carboxyl-terminal hydrolase 54 1 NS(0.02)S(0.164)S(0.401)PVS(0.415)LDAALPESSNVYRDPSAK 82.294 1.9487e-05 8750200.0 30701.0 42736.0 39670.0 38044.0 39173.0 35558.0 32502.0 34348.0 35817.0 32212.0 True False 30263.198110126144 42637.04741769204 36408.485730628345 40841.88267106364 36868.92115708122 34037.26722974649 34184.79452649264 35943.93347353883 31782.912290269334 37779.80128020798 0.8010417494170456 1.1285672759752885 0.9637024149648442 1.0810507542944598 0.9758897587530733 0.9009382282690267 0.9048431534339835 0.9514061020847423 0.8412673231004979 1.0 15.205327492794725 -6.622415915685142 4.973210858561577 0.9162133533670148 1.0041142647853774 0.1327003081747573 0.08866387544078279 0.3568431624165814 14.49023533605695 0.02790482797299556 0.027864999098795164 2.3855256154484886e-07 6.622415915685142 0.08790091141836254 NSSSPVS(ph)PASVPGQR ddPTM_PC-9_AZD4547_30min_R2 4 NSSSPVSPASVPGQR 15 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 NSS(0.002)S(0.02)PVS(0.978)PASVPGQR;NSS(0.001)S(0.014)PVS(0.985)PASVPGQR;NSS(0.011)S(0.125)PVS(0.864)PASVPGQR;NS(0.016)S(0.043)S(0.454)PVS(0.487)PASVPGQR 196.65 1.0099e-09 51372400.0 75351.0 66977.0 80446.0 119807.0 96719.0 99420.0 95826.0 107244.0 86144.0 102757.0 True False 99311.05060183567 88626.0054433791 79379.23347751731 92187.34714969831 83291.23634146467 93203.25168339022 104354.32836044021 90671.9040219549 90697.39597353853 99159.5087067967 1.0015282638751979 0.8937721313791099 0.800520641063608 0.9296874132594357 0.8399722571009031 0.9399325682318733 1.0523885174643615 0.9144045306846097 0.9146616109375888 1.0 16.597463503051294 -6.989556498634923 24.037127383002474 0.9679349692492626 0.8900163306352119 0.25777708975520885 0.06196840033504652 189.95114442058147 437194.4881157358 0.02216985682218684 0.01952861793227902 1.0243385124593979e-07 6.989556498634923 -0.07791863861405068 NSSSPVS(ph)PASVPGQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSSSPVSPASVPGQR 15 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 NSSSPVS(0.996)PAS(0.004)VPGQR;NS(0.017)S(0.058)S(0.197)PVS(0.669)PAS(0.058)VPGQR 110.57 0.00051257 16083800.0 21325.5 24175.1 30480.0 28019.0 34838.0 26229.0 27738.0 25432.0 30736.0 20414.3 True False 24935.485952175753 26575.044160330068 31206.75879604372 26449.18626882363 28011.743986675534 24853.505066484402 25110.455834270633 24764.436947431386 31185.455853200798 24115.2509904901 1.0340131214893478 1.10200155788592 1.2940673438709043 1.096782541440432 1.1615779573566132 1.0306135762918425 1.0412686910939883 1.0269201410011155 1.2931839633557556 1.0 14.557658205235034 -6.745420291754905 24.949625997399547 1.0777592376660996 1.1421210618817381 0.08188802314855892 0.09869748453332367 626.3405862575343 975518.9045951762 0.032715788996706394 0.03261647121669091 1.7971308863547558e-07 6.745420291754905 0.06436182421563852 NSSSPVS(ph)PASVPGQR ddPTM_PC-9_Lapatinib_30min_R1 3 NSSSPVSPASVPGQR 15 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 NS(0.003)S(0.002)S(0.016)PVS(0.963)PAS(0.016)VPGQR;NS(0.004)S(0.014)S(0.304)PVS(0.678)PASVPGQR;NS(0.01)S(0.003)S(0.032)PVS(0.954)PAS(0.001)VPGQR 143.69 7.3995e-05 45762000.0 63840.0 60030.0 64672.0 60329.0 74547.0 62787.0 55121.0 53970.0 60448.0 55039.0 True False 62929.62989317784 59891.00422323217 59354.91780113932 64765.79591164434 70162.29202504098 60101.74637364569 57974.89567087563 56477.643227171604 53639.70969434065 64552.41781514241 0.9748609273379701 0.9277887064546668 0.9194840380899895 1.0033055012302246 1.0869041687325092 0.9310533734887819 0.8981057198647041 0.8749113532649637 0.8309481117802235 1.0 15.978183512333505 -6.995065055524249 24.98981065462363 0.8939975582938201 0.9802782908499597 0.30260122757598407 0.0582860929257663 170.38895851246696 862817.711525835 0.02160930118873747 0.018992902578151897 1.0114279351737527e-07 6.995065055524249 0.08628073255613955 NSSSSS(ph)SPSERPR ddPTM_PC-9_AZD4547_30min_R2 1 NSSSSSSPSERPR 13 1 B7WPE2;Q32P44;G3V1D0;H0Y3M3;Q32P44-2 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 NS(0.004)S(0.019)S(0.019)S(0.096)S(0.502)S(0.359)PS(0.001)ERPR 62.376999999999995 0.023443000000000002 2942700.0 5055.8 3269.5 3838.4 5448.6 5646.5 4432.2 4935.3 4788.3 6278.4 4932.9 True False 6663.4392328271715 4326.301936442782 3787.500308033995 4192.509450030851 4862.580940684656 4155.0538333446275 5374.532139057043 4048.378259187715 6610.26340639236 4760.200672457905 1.399823177913745 0.9088486461241808 0.795659798534993 0.8807421658268182 1.0215075529943756 0.8728736705125473 1.1290557917344968 0.850463780363561 1.3886522567501727 1.0 12.21680667816536 -8.249700538057054 24.936422908627843 1.1943261578367337 0.9728537152279634 0.16753955118915465 0.18802891173742162 1050.3081037440434 2231146.189826506 0.12468441601402715 0.04631516119226312 5.62729213835333e-09 8.249700538057054 -0.2214724426087703 NSSSSS(ph)SPSERPR ddPTM_PC-9_Lapatinib_30min_R1 1 NSSSSSSPSERPR 13 1 B7WPE2;Q32P44;G3V1D0;H0Y3M3;Q32P44-2 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 NS(0.001)S(0.006)S(0.051)S(0.156)S(0.482)S(0.299)PS(0.005)ERPR 69.37899999999999 0.014462000000000001 825590.0 1164.3 920.42 1030.6 769.42 1217.8 927.83 391.7 813.58 1039.3 562.71 True False 1147.6968684935293 918.2888240404367 945.8680462310452 826.0057135098771 1146.1713982869187 888.1488737773685 411.98030939718024 851.3818969198122 922.2430896858165 659.9736737360558 1.739004015109441 1.3914022037304614 1.4331905708852979 1.2515737314701172 1.7366926044163824 1.345733790788399 0.624237489754696 1.2900240279285844 1.3973937543070094 1.0 9.366264666476193 -7.0102966036719865 24.69854998428681 1.0853543504477177 1.490709140348625 0.4287877193139389 0.23488009653808825 444.9096403227069 1067208.6911827778 0.08658465740359693 0.07177558848244067 9.76570039573765e-08 7.0102966036719865 0.40535478990090734 NSSTDQGS(ph)DEEGSLQK ddPTM_PC-9_AZD4547_30min_R2 1 NSSTDQGSDEEGSLQK 16 0 Q12789;Q12789-3 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 1 NSSTDQGS(0.934)DEEGS(0.066)LQK 105.53 0.0011214 5644400.0 30544.0 32234.0 34123.0 50556.0 46210.0 41368.0 35046.0 49096.0 32345.0 45068.0 True False 40256.356645332686 42653.01012977418 33670.50672442788 38901.09528241378 39794.539142661444 38781.2524204234 38165.026106901954 41509.34131384416 34054.690666373775 43490.18303763157 0.9256423825694021 0.9807503015764961 0.7742093588176708 0.8944799162779585 0.91502349181257 0.8917242860731677 0.8775549662294634 0.9544531297540548 0.7830431671650274 1.0 15.408402160251354 NSSTDQGS(ph)DEEGSLQK ddPTM_PC-9_Lapatinib_30min_R1 2 NSSTDQGSDEEGSLQK 16 0 Q12789;Q12789-3 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 1 NSS(0.001)T(0.002)DQGS(0.873)DEEGS(0.125)LQK;NSSTDQGS(1)DEEGSLQK 128.72 1.9957e-05 21212400.0 77509.0 123091.0 109326.0 130424.0 120146.0 89716.0 77382.0 75046.0 93195.0 73675.0 True False 76403.70744659011 122805.99035218854 100337.63829056425 140015.81604170983 113079.24849612426 85879.05581821072 81388.4613269661 78532.91112889229 82698.39771314325 86409.62558423348 0.8842036628443732 1.4212072963153313 1.161185893494626 1.6203729051599718 1.3086418061827245 0.9938598302858569 0.9418911466943846 0.9088444788172025 0.9570507585700337 1.0 16.39890440963672 -6.796040279634223 5.226436671739209 0.9493214234755644 1.300289512956885 0.4452792316964631 0.17737296710528758 0.1682297114283379 11.32978222778932 0.06206418141332967 0.0561569317751182 1.5994096808293477e-07 6.796040279634223 0.35096808948132063 NSSTDQGS(ph)DEEGSLQKEQESAMDK ddPTM_PC-9_Lapatinib_30min_R1 1 NSSTDQGSDEEGSLQKEQESAMDK 24 1 Q12789;Q12789-3 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 1 NS(0.001)S(0.006)T(0.015)DQGS(0.893)DEEGS(0.07)LQKEQES(0.013)AMDK 59.242 0.018469 0.0 6454.5 7739.2 5872.6 4648.3 5771.6 7971.1 4224.7 1727.2 6669.9 4833.8 True False 6362.4576463896665 7721.2803578950325 5389.777496891557 4990.151488274238 5432.1258354021875 7630.194634541658 4443.43429438414 1807.4520174536003 5918.6656248392455 5669.315889366367 1.122261974910128 1.3619421652579682 0.9506927470739239 0.8802034646956255 0.9581624911024866 1.3458757252975102 0.7837690439367566 0.3188130724632476 1.043982332319949 1.0 12.468958941775961 -7.436366130229348 8.3723390443961 0.7198149915194938 1.0901891430233073 0.2851227096713179 0.2378451941952374 0.3742829449397134 33.15266268787101 0.09956642745145981 0.06686920982122713 3.6612878109515026e-08 7.436366130229348 0.3703741515038135 NSSTMLYS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 NSSTMLYSR 9 0 Q96DR7;Q96DR7-4 Q96DR7 ARHGEF26 Rho guanine nucleotide exchange factor 26 1 NSSTMLY(0.366)S(0.634)R 79.71300000000001 0.019745 12451000.0 94474.0 128120.0 121390.0 115090.0 99652.0 113260.0 88944.0 126500.0 109790.0 110780.0 True False 124514.76681872552 169532.28447684628 119780.28928518291 88557.77862277477 85817.03991872976 106177.83429552201 96859.84369264086 106952.33168081507 115593.27525927278 106901.62591880793 1.1647602714040552 1.5858718987642575 1.120472099986172 0.8284044125767988 0.8027664610443627 0.9932293674949749 0.9060652058389287 1.0004743217099958 1.0813051182875943 1.0 16.70592427031245 -5.499244394260798 5.940111136589598 0.9407909430027428 1.3738102090727242 0.6599950171723079 0.12305597701082226 0.09430332181542889 11.248579280289071 0.03216651867516193 0.06404992723102197 3.1677843269114537e-06 5.499244394260798 0.4330192660699814 NSSTMLYS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 NSSTMLYSR 9 0 Q96DR7;Q96DR7-4 Q96DR7 ARHGEF26 Rho guanine nucleotide exchange factor 26 1 NSSTMLY(0.376)S(0.624)R 80.455 0.018664 24874000.0 53787.0 97729.0 84932.0 72953.0 85848.0 99637.0 109170.0 93706.0 77547.0 80048.0 True False 53019.987516672205 97502.71450495193 77949.21880700091 78318.20698407367 80798.58942366186 95375.75777519114 114822.2884270874 98059.92285057127 68812.84025388818 93884.19014274474 0.5647381889970909 1.0385424250526682 0.8302699175280124 0.8342001658106224 0.8606197625054114 1.0158873142557716 1.2230204920818688 1.0444774855220842 0.7329545064963843 1.0 16.5185946117307 -6.732904070640224 4.910382214706245 1.0206071766247755 0.8361152482784843 0.24407393174016556 0.15474888953707275 0.2872188650652339 16.989935906313374 0.05322742326817227 0.0512344331099106 1.8496771407437462e-07 6.732904070640224 -0.18449192834629125 NSSTPGLQVPVS(ph)PTVPIQNQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSSTPGLQVPVSPTVPIQNQK 21 0 Q03164-2;Q03164;Q03164-3 Q03164-2 KMT2A Histone-lysine N-methyltransferase 2A;MLL cleavage product N320;MLL cleavage product C180 1 NSSTPGLQVPVS(0.732)PT(0.268)VPIQNQK;NSSTPGLQVPVS(0.967)PT(0.032)VPIQNQK 80.359 0.0037325 0.0 21688.0 22351.0 19333.0 27057.0 34288.0 32906.0 31660.0 40088.0 30306.0 29585.0 True False 25359.350042474412 24569.859567386986 19793.9720408108 25541.08400997754 27569.5125384675 31180.351432297684 28660.93560144957 39035.73247674696 30749.167916680868 34948.52630526888 0.7256200110117721 0.703029917564301 0.5663750130095367 0.7308200576722726 0.788860517254803 0.892179291336725 0.8200899617655298 1.1169493138502349 0.8798416175861781 1.0 15.092944001476175 -6.816134946825243 0.9949637249972993 0.9864077201060653 0.6656957205100021 0.7103866655179418 0.08075072792321429 0.27954962279198153 0.5907171211666935 0.04681198547930825 0.040355447293945135 1.5270914766460915e-07 6.816134946825243 -0.3207119995960631 NSSYFVEWIPNNVK ddPTM_PC-9_AZD4547_30min_R2 1 NSSYFVEWIPNNVK 14 0 P04350;K7ESM5;Q9BUF5;P68371;A0A0B4J269;Q13509;Q13509-2;Q5JP53;P07437;Q5ST81;Q9BVA1;Q13885 P04350;P68371;A0A0B4J269;Q5JP53 TUBB4A;TUBB6;TUBB4B;TUBB3;TUBB;TUBB2B;TUBB2A Tubulin beta-4A chain;Tubulin beta-6 chain;Tubulin beta-4B chain;Tubulin beta-3 chain;Tubulin beta chain;Tubulin beta-2B chain;Tubulin beta-2A chain 0 119.21 0.00048106 3684800.0 16979.0 16425.0 19497.0 27171.0 22513.0 22901.0 18696.0 23494.0 19124.0 23199.0 False True 22377.96881486066 21734.06004161882 19238.457040886515 20907.14573776533 19387.458552666893 21468.99684974172 20359.90778104887 19863.542138411583 20134.85559758022 22386.81007122604 0.9996050685051935 0.9708422045154972 0.8593657148864576 0.9339046372058817 0.8660214872500197 0.9590020543988091 0.9094599773827374 0.8872877410945818 0.8994070854006898 1.0 14.450361350692754 -5.063161260684553 6.70655917705148 0.9107281103169194 0.9929765368320066 0.33889908334027163 0.04025458783080746 0.20045009760123142 17.699768123839174 0.00949084590407751 0.026243632639394106 8.646468015819047e-06 5.063161260684553 0.08224842651508724 NSSYFVEWIPNNVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSSYFVEWIPNNVK 14 0 P04350;K7ESM5;Q9BUF5;P68371;A0A0B4J269;Q13509;Q13509-2;Q5JP53;P07437;Q5ST81;Q9BVA1;Q13885 P04350;P68371;A0A0B4J269;Q5JP53 TUBB4A;TUBB6;TUBB4B;TUBB3;TUBB;TUBB2B;TUBB2A Tubulin beta-4A chain;Tubulin beta-6 chain;Tubulin beta-4B chain;Tubulin beta-3 chain;Tubulin beta chain;Tubulin beta-2B chain;Tubulin beta-2A chain 0 ; 130.69 8.6159e-05 15286300.0 67438.0 71802.0 63369.0 85366.0 84087.0 80453.0 87276.0 71579.0 69370.0 64152.0 False True 78853.921438786 78930.02803711354 64879.9572882708 80583.21978030606 67610.75597358019 76233.9030505879 79008.58545647866 69700.12709421937 70384.40501485368 75782.24977304744 1.0405328645551906 1.0415371445621247 0.8561365950809483 1.063352170483676 0.8921714012985993 1.005959882147773 1.042573764873614 0.9197421203904238 0.9287716480526875 1.0 16.209572349803032 -5.101091140579908 21.49213002540087 0.9649188018455518 1.0412009197283105 0.1967911677391153 0.0625371450658671 16.939832948887553 3590.1750818569412 0.015194456614302425 0.04020102487257687 7.923350344407489e-06 5.101091140579908 0.07628211788275874 NSSYFVEWIPNNVK ddPTM_PC-9_Lapatinib_30min_R1 2 NSSYFVEWIPNNVK 14 0 P04350;K7ESM5;Q9BUF5;P68371;A0A0B4J269;Q13509;Q13509-2;Q5JP53;P07437;Q5ST81;Q9BVA1;Q13885 P04350;P68371;A0A0B4J269;Q5JP53 TUBB4A;TUBB6;TUBB4B;TUBB3;TUBB;TUBB2B;TUBB2A Tubulin beta-4A chain;Tubulin beta-6 chain;Tubulin beta-4B chain;Tubulin beta-3 chain;Tubulin beta chain;Tubulin beta-2B chain;Tubulin beta-2A chain 0 ; 238.07 2.2171e-26 57066000.0 132988.0 113836.0 147830.0 108288.0 123044.0 103746.0 124595.0 113727.0 106382.0 126259.0 False True 131091.56673298788 113572.41973606296 135675.98804030212 116251.86075817868 115806.7938338116 99309.02542373801 131045.91945198298 119011.17160082514 94400.13890787693 148082.6999204576 0.8852591612889521 0.7669526541389926 0.9162176818303573 0.7850468746222428 0.7820413451133524 0.6706321905062623 0.8849509059625067 0.8036804546699364 0.6374825618291928 1.0 17.1760435789607 -10.858133521325914 5.730698573497219 1.0000318986813361 0.7943033410805052 0.34878748756638644 0.08503669094601503 3.406661673931878e-05 3.951664599198592e-06 0.08093414971015474 0.019626374574090003 1.3863295443478862e-11 10.858133521325914 -0.20572855760083097 NST(ph)ELAPPLPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSTELAPPLPVR 12 0 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 NS(0.289)T(0.711)ELAPPLPVR;NS(0.209)T(0.791)ELAPPLPVR 160.87 0.0014652 4639900.0 16674.6 34394.0 21934.0 24259.0 25140.0 15926.5 31638.0 19343.4 16601.6 16936.9 True False 19497.28044163794 37808.409017972735 22456.989745158236 22899.846878739143 20213.997469000016 15091.286302999126 28641.019600715765 18835.656246026436 16844.366992858493 20007.425897573372 0.9745021944078621 1.8897188079831089 1.122432733732227 1.144567371933467 1.010324745046373 0.7542842532696569 1.43151946419002 0.9414332629521793 0.8419057543480136 1.0 14.288247945409333 -5.499407233909223 23.416785501835697 1.029871679692149 1.450601997845653 0.27099516582377225 0.2672725224540099 393.25327546026557 392334.14573553123 0.06650154388603251 0.13679205159904742 3.166596782026973e-06 5.499407233909223 0.42073031815350403 NST(ph)ELAPPLPVRR ddPTM_PC-9_AZD4547_30min_R2 1 NSTELAPPLPVRR 13 1 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 NS(0.5)T(0.5)ELAPPLPVRR 78.249 0.012912 8151400.0 9882.5 12043.0 14087.0 18879.0 17407.0 13800.0 15721.0 16018.0 14447.0 14032.0 True False 13024.929431230368 15935.66423629925 13900.197175717718 14526.738227642401 14990.338516691356 12937.083818454908 17120.138544387537 13542.786157022076 15210.638925864952 13540.743951008386 0.961906485962346 1.1768677034257422 1.0265460469535401 1.0728168467110397 1.107054277883677 0.955418983274658 1.2643425358554683 1.0001508193361517 1.1233237243757355 1.0 13.725019384706497 NST(ph)ELAPPLPVRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSTELAPPLPVRR 13 1 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 NS(0.109)T(0.891)ELAPPLPVRR;NS(0.421)T(0.579)ELAPPLPVRR 120.57 0.00017869999999999998 2322800.0 12063.5 9900.5 12924.5 14633.8 18777.0 16659.2 19716.0 12905.0 14732.599999999999 14959.6 True False 14105.612285014293 10883.35620987494 13232.669096439206 13813.91562941972 15097.781641822337 15785.5622251545 17848.35774852114 12566.257423977751 14948.036403659093 17671.657059871548 0.798205410914466 0.6158650642100029 0.7488074859990177 0.7816989421319231 0.8543500810745182 0.8932700635641037 1.0099991012756149 0.7110967229277532 0.845876329141923 1.0 14.109149706364368 -6.040791640336156 1.8184612606888468 0.8805246893148746 0.7063879807091329 0.41948699462019834 0.08882392403753096 0.35736804098829505 2.364768131395875 0.029794867327180466 0.04696390222953555 9.103499226888532e-07 6.040791640336156 -0.1741367086057417 NST(ph)PSEPGSGR ddPTM_PC-9_AZD4547_30min_R2 5 NSTPSEPGSGR 11 0 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 NS(0.004)T(0.959)PS(0.037)EPGSGR;NS(0.004)T(0.735)PS(0.207)EPGS(0.054)GR;NS(0.03)T(0.958)PS(0.012)EPGSGR;NS(0.004)T(0.584)PS(0.268)EPGS(0.143)GR;NS(0.004)T(0.796)PS(0.2)EPGSGR 148.89 0.00016534 551365000.0 435867.0 458217.0 493588.0 508908.0 556722.0 561530.0 483092.0 521660.0 464662.0 513090.0 True False 574463.6394031962 606326.6843281848 487042.7006153297 391587.1231502221 479430.76002122415 526417.4403316664 526086.2521267891 441049.43355426023 489223.0846937257 495126.8752724405 1.16023522069389 1.2245885137916566 0.9836725189828113 0.7908823832977229 0.9682988017110167 1.063197064473643 1.0625281688401853 0.8907806374105133 0.9880762065774227 1.0 18.9174387347245 -5.289530174988588 7.5913509795890945 0.9646010390109632 1.1925209100594902 0.5754710290376941 0.0769122369813712 0.14793803801446864 34.49490545703399 0.021645712446042135 0.04670803673586025 5.134165038391053e-06 5.289530174988588 0.22791987104852707 NST(ph)PSEPGSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 NSTPSEPGSGR 11 0 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 NS(0.005)T(0.979)PS(0.016)EPGSGR;NS(0.013)T(0.97)PS(0.017)EPGSGR;NS(0.004)T(0.887)PS(0.109)EPGSGR;NS(0.004)T(0.729)PS(0.238)EPGS(0.029)GR;NS(0.002)T(0.881)PS(0.116)EPGS(0.001)GR;NS(0.156)T(0.568)PS(0.271)EPGS(0.006)GR 129.34 0.00064625 502769560.0 402847.2 465948.2 403906.3 501372.4 524314.6 396734.3 499887.5 355322.4 346356.6 330159.0 True False 471041.2743651177 512204.4579516234 413536.958015173 473282.1298992522 421578.91795384855 375928.8548971807 452534.5371279085 345995.56349520234 351421.4100326882 390014.2131627943 1.2077541239977894 1.313296902176809 1.060312532360353 1.213499698026906 1.0809321909965341 0.9638850129296844 1.1603026809154204 0.8871357807434103 0.901047700756492 1.0 18.57316717504206 -6.312433859788876 0.5345261916701108 0.9369989405979123 1.2769010729660626 0.5830951478292128 0.08770271815580646 0.8055015271706822 0.46613811197418314 0.06925278766018297 0.13903502363575976 4.870416927846929e-07 6.312433859788876 0.33990213236815026 NST(ph)PSEPGSGR ddPTM_PC-9_Lapatinib_30min_R1 4 NSTPSEPGSGR 11 0 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 NS(0.003)T(0.911)PS(0.087)EPGSGR;NS(0.004)T(0.968)PS(0.028)EPGSGR;NS(0.037)T(0.876)PS(0.086)EPGS(0.001)GR;NS(0.002)T(0.716)PS(0.282)EPGSGR 163.71 0.0003751 301793900.0 346586.0 489504.0 480589.0 437920.0 502816.0 484182.0 427663.0 479435.0 488128.0 374213.0 True False 341643.6200839118 488370.58356303594 441076.82754718716 470126.09765829577 473241.3514542912 463474.6645433692 449805.2975688696 501711.3003635173 433149.88442428416 438895.21844252 0.7784172753038439 1.1127270542980305 1.004970683235987 1.0711579390784953 1.0782558833373788 1.0560029935802735 1.0248580496389674 1.1431231858572275 0.9869095543154378 1.0 18.74351702723441 -4.754337520314285 24.999775518801865 1.056637027545925 0.7784167934370523 0.7462540598349858 0.04801415519662576 111.9707746560437 394122.4611206447 0.010893668642854551 0.10719618835052763 1.760607224791174e-05 4.754337520314285 -0.27822023410887264 NST(ph)PSSSSSLQK ddPTM_PC-9_AZD4547_30min_R2 1 NSTPSSSSSLQK 12 0 Q9P0U3;Q9P0U3-2;F8VRZ8 Q9P0U3 SENP1 Sentrin-specific protease 1 1 NS(0.006)T(0.993)PSSSSSLQK 151.07 0.00044711 3608700.0 20065.0 20669.0 20334.0 30504.0 29384.0 26157.0 24880.0 27127.0 23622.0 29018.0 True False 26445.252622073098 27349.85004567545 20064.35787400042 23471.774082102005 25304.538804760097 24521.39865502355 27094.27180105349 22935.145466446378 24870.610694731193 28002.088652391794 0.944402860456421 0.9767075015434381 0.7165307603683565 0.8382151193602898 0.9036661200127554 0.8756989151567827 0.9675803879272141 0.8190512411825885 0.8881698434522624 1.0 14.773246820150607 -6.295143887060379 22.78154322490534 0.9012415214356596 0.8657719175581818 0.051683798145889304 0.07953636101111106 868.056050145885 586732.7688472795 0.025712053171817968 0.029157913988239675 5.068227638901601e-07 6.295143887060379 -0.03546960387747777 NST(ph)PSSSSSLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSTPSSSSSLQK 12 0 Q9P0U3;Q9P0U3-2;F8VRZ8 Q9P0U3 SENP1 Sentrin-specific protease 1 1 NS(0.186)T(0.607)PS(0.085)S(0.026)S(0.057)S(0.039)SLQK;NS(0.006)T(0.748)PS(0.096)S(0.021)S(0.039)S(0.074)S(0.016)LQK 118.52 0.0011404000000000002 3249400.0 38036.0 31150.0 35028.0 47225.0 50849.0 38627.0 44357.0 35392.0 33282.0 30497.0 True False 44474.7435547564 34242.366136821816 35863.200364429766 44579.13635551576 40885.5034726007 36601.3321210528 40155.183843130086 34462.99750092372 33768.68628664201 36025.86468588084 1.2345225837753957 0.9504939419328355 0.9954847906394645 1.2374203018917986 1.1348930505649857 1.0159737299906502 1.1146209589486298 0.9566181908863484 0.9373456149097386 1.0 15.136745437654156 -7.766581168111675 24.965870900672595 0.9602363787281593 1.0917113069122344 0.31237420978854435 0.09003998257863843 163.99395871042046 796249.673144201 0.04844301929940673 0.024389595560317754 1.7116652425909367e-08 7.766581168111675 0.13147492818407513 NST(ph)TIMSR ddPTM_PC-9_Lapatinib_30min_R1 1 NSTTIMSR 8 0 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 NS(0.036)T(0.746)T(0.218)IMSR 106.16 0.009366 9980200.0 32661.0 29276.0 31307.0 32499.0 31625.0 33033.0 34841.0 35254.0 34705.0 23789.0 True False 32195.24815070616 29208.21322071209 28733.059308514803 34889.08487348588 29764.879677142246 31620.255593684 36644.89650167771 36892.02954105446 30796.157440148458 27900.896953150008 1.1539144495880203 1.0468557075336062 1.0298256488586057 1.2504646331646663 1.066807268853118 1.1333060599012061 1.3133949264502232 1.3222524567221612 1.1037694412426973 1.0 14.768023881856998 -7.0211778442481405 24.064775141712325 1.2133717276155682 1.108543113310722 0.07673691064405652 0.10646301738485561 845.228803269961 960446.5483018279 0.03951837245131242 0.03097077539869172 9.524060724283389e-08 7.0211778442481405 -0.10482861430484625 NSTFSEIFK ddPTM_PC-9_Lapatinib_30min_R1 2 NSTFSEIFK 9 0 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 ; 119.22 0.0080646 19142000.0 106778.0 105551.0 97079.0 92543.0 89559.0 67797.0 100036.0 87487.0 76799.0 91946.0 False True 105255.326139313 105306.6031445342 89097.53935577671 99348.92093439795 84291.31569976854 64897.480352526036 105215.37460009287 91551.96540699573 68149.08789067745 107838.74358965625 0.9760436985414669 0.9765191955985943 0.8262108439876411 0.9212729824861142 0.7816422270321559 0.6018011541331693 0.9756732237205421 0.8489709946488775 0.6319536524831527 1.0 16.7185160675795 -5.35550940046379 1.2050488831424022 0.8049465494160783 1.0033015216477 0.18968215578041925 0.12391533097828905 1.1201226349187179 2.553996770042664 0.04048148365491543 0.21638644599819867 4.41052816267692e-06 5.35550940046379 0.19835497223162157 NSTPS(ph)EPGSGR ddPTM_PC-9_Lapatinib_30min_R1 2 NSTPSEPGSGR 11 0 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 NS(0.166)T(0.232)PS(0.595)EPGS(0.007)GR;NS(0.004)T(0.121)PS(0.867)EPGS(0.007)GR 98.0 0.0051576999999999994 164323000.0 17587.9 21482.3 27838.0 25199.0 24162.0 24091.0 24649.0 22726.0 28207.0 22945.4 True False 17337.09332077416 21432.55905421857 25549.26709778756 27052.21852139976 22740.838664319705 23060.68408886391 25925.204611516725 23781.932925341887 25030.030627121956 26911.481817176344 0.644226633024299 0.7964094730948322 0.9493816532050143 1.0052296155663043 0.8450236526851259 0.8569087442128642 0.9633510628526548 0.8837095291483722 0.9300874175998163 1.0 14.715934211309422 -4.935964486295343 2.6635917963245426 0.9229441506447226 0.6305994374969219 0.743496110361995 0.05266882927938454 0.17637247662232783 2.109039711447144 0.014181011757924777 0.09948244002963912 1.1588721171091286e-05 4.935964486295343 -0.29234471314780064 NSTPSEPGS(ph)GRGPPQEEEEEEDEEEEATKEDAEAPGIR ddPTM_PC-9_AZD4547_30min_R2 1 NSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIR 38 2 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 NS(0.005)T(0.01)PS(0.107)EPGS(0.875)GRGPPQEEEEEEDEEEEAT(0.003)KEDAEAPGIR 51.034 0.00078852 5668000.0 4738.5 2991.5 3754.1 6416.1 5059.2 4699.5 3248.9 4049.0 3465.6 4761.3 True False 6245.244433077165 3958.443873029084 3704.318181114637 4936.967272756841 4356.81740814873 4405.639522089046 3538.045806046732 3423.3200867637897 3648.784540837375 4594.608336226932 1.3592550171982074 0.8615410897634285 0.8062315457679693 1.0745131927417022 0.9482456586770843 0.9588716164013523 0.7700429606045935 0.7450733199110944 0.7941448484450663 1.0 12.165726170014025 -7.156842084835147 4.265614842828533 0.806430681295804 0.990611418747802 0.22935986777068418 0.1544198128509723 0.35077555466215693 10.87419836063247 0.06081448890583149 0.046276642550911885 6.968798626979168e-08 7.156842084835147 0.18418073745199803 NSTPSEPGS(ph)GRGPPQEEEEEEDEEEEATKEDAEAPGIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIR 38 2 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 NS(0.018)T(0.018)PS(0.129)EPGS(0.833)GRGPPQEEEEEEDEEEEAT(0.002)KEDAEAPGIR 52.868 0.00037605 4037300.0 3359.6 864.66 1834.3 3203.3 2724.0 4436.3 3544.3 4893.5 4125.4 2044.5 True False 3928.313924875368 950.4977304611357 1878.036668621488 3023.829486238721 2190.251754397617 4203.6526183401875 3208.5582454901364 4765.050810091834 4185.726170509973 2415.1516657469065 1.6265288762561017 0.3935561248354091 0.7776061003774224 1.2520246778388453 0.9068795908186837 1.7405335979345926 1.3285121141648313 1.9729820191719518 1.7331111043146439 1.0 11.237898074365164 -6.756802289615047 24.990438163892833 1.601681944833812 0.9607206359573558 0.3421762022361132 0.38695275535671053 119.00804265818772 641363.9712257935 0.12641769781783274 0.12244353934995346 1.7506434789080163e-07 6.756802289615047 -0.6409613088764562 NSTPSEPGS(ph)GRGPPQEEEEEEDEEEEATKEDAEAPGIR ddPTM_PC-9_Lapatinib_30min_R1 2 NSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIR 38 2 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 NS(0.001)T(0.007)PS(0.118)EPGS(0.869)GRGPPQEEEEEEDEEEEAT(0.004)KEDAEAPGIR;NS(0.011)T(0.024)PS(0.11)EPGS(0.853)GRGPPQEEEEEEDEEEEAT(0.002)KEDAEAPGIR 52.486000000000004 0.00046192 14998400.0 39626.3 11261.1 15943.8 15039.2 15498.5 12524.6 8019.1 7761.25 13013.2 9599.9 True False 39061.22169542657 11235.025614829921 14632.9623088478 16145.232937300505 14586.908701223361 11988.9520542686 8434.289760242355 8121.8660088361285 11547.516380928962 11259.229923937304 3.4692622816398644 0.9978502695769695 1.299641485936608 1.4339553456471725 1.2955511877603065 1.0648110159629918 0.7491000554408183 0.7213518210129904 1.0256044559831536 1.0 13.458820537082259 -4.7603531042691465 24.999963200449486 1.0727501063553193 3.469265125596746 0.9166294445559504 0.21748747704299837 8.202099437839436 188679.91387120102 0.06336495778532722 0.37793303766616376 1.736388479456339e-05 4.7603531042691465 2.3965150192414266 NSTS(ph)SIEPR ddPTM_PC-9_AZD4547_30min_R2 1 NSTSSIEPR 9 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6 C9J840;O95819-6 MAP4K4 1 NS(0.072)T(0.047)S(0.809)S(0.072)IEPR 103.43 0.0028584 15499000.0 39971.0 60094.0 58087.0 69698.0 72352.0 80459.0 63132.0 66000.0 60053.0 67179.0 True False 52680.94655155164 79518.2102977802 57316.72842662845 53630.202923365694 62307.17368642811 75427.88601080187 68750.6256971105 55801.216529120786 63227.27897937064 64827.08365769626 0.8126379219790395 1.2266201996322537 0.884147877595043 0.8272808199509176 0.9611287469821421 1.1635242826760583 1.0605231921295666 0.8607701192261804 0.9753219705706182 1.0 15.9843090521562 -4.510029803480497 20.007953838689012 0.9904291769578982 0.49128310731720204 0.16924377067168905 0.1210637028981277 16427453.807007277 481470526.9106905 0.031253512883316584 238629325.16756985 3.090083368111843e-05 4.510029803480497 -0.4991460696406962 NSTS(ph)SIEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NSTSSIEPR 9 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6 C9J840;O95819-6 MAP4K4 1 NS(0.018)T(0.012)S(0.571)S(0.4)IEPR;NS(0.002)T(0.01)S(0.764)S(0.223)IEPR 122.18 0.001572 24382000.0 96537.0 110899.0 129282.0 93104.0 139892.0 82130.0 112520.0 75976.0 83129.0 74294.0 True False 112878.80740733811 121908.31981404184 132364.57318471558 87887.68472724082 112481.1668231246 77822.95821839805 101861.29102574564 73981.710503226 84344.60436038289 87762.91408901977 1.2861788897853 1.3890641745371817 1.5082062230802342 1.0014216783879177 1.2816480399572032 0.8867408178750832 1.1606416227522434 0.842972356503395 0.9610506355204931 1.0 16.421323809483575 -6.223835193868869 0.9821726150364585 0.9630107778394456 1.394271557624249 0.5742010373950788 0.14025448649217542 0.38448001902139584 0.7809247095005101 0.06200820750851843 0.10167843132647603 5.972618926119628e-07 6.223835193868869 0.4312607797848035 NSTS(ph)SIEPR ddPTM_PC-9_Lapatinib_30min_R1 3 NSTSSIEPR 9 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6 C9J840;O95819-6 MAP4K4 1 NS(0.357)T(0.03)S(0.391)S(0.222)IEPR;NS(0.029)T(0.018)S(0.914)S(0.038)IEPR;NS(0.028)T(0.086)S(0.729)S(0.157)IEPR 99.73200000000001 0.004046500000000001 35572300.0 79882.0 126126.0 104374.0 92956.0 111134.0 98550.0 95438.0 93245.0 111583.0 88248.0 True False 78742.86803143547 125833.96299615853 95792.77261529113 99792.29433212588 104597.31661785071 94335.24623127042 100379.31265827948 97577.50310760822 99015.34751891904 103501.54921693135 0.7607892696021045 1.215768884119987 0.925520181485562 0.9641623249809416 1.0105869661778948 0.9114380117494757 0.9698339147358277 0.9427636962524418 0.9566557048473779 1.0 16.659292836662445 -6.741195639928407 24.96029029875518 0.9534169438341621 0.9853296690636855 0.0034611377423836576 0.10607049630023552 1281.0690532431013 1579540.0111493967 0.0329753230092573 0.03293681735345208 1.8146979978496196e-07 6.741195639928407 0.031912725229523375 NSTSS(ph)QSQTSTASR ddPTM_PC-9_Lapatinib_30min_R1 1 NSTSSQSQTSTASR 14 0 Q6UN15;Q6UN15-5;A0A0B4J203;Q6UN15-4 Q6UN15 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 NS(0.005)T(0.204)S(0.203)S(0.374)QS(0.203)QT(0.006)S(0.002)T(0.001)AS(0.003)R 105.02 0.0040622 0.0 1179.6 854.09 729.09 1106.8 1063.8 2582.3 878.74 558.19 998.39 415.99 True False 1162.7786876878538 852.1124070801328 669.1470345687881 1188.197764176564 1001.2293755112698 2471.8610486353086 924.2368574921586 584.1255451727801 885.9408046872157 487.8933172281671 2.38326422319917 1.7465137910090205 1.3715027669785775 2.435363884315911 2.052148164683791 5.06639661038711 1.8943421130319194 1.1972403075560252 1.8158494355291581 1.0 8.930421912292998 -5.790396828633448 24.91779235972031 2.3164229652107013 1.8250349169639621 0.018134601387929328 1.076293930256978 799.2579667196279 687755.7568650653 0.3209701906614325 0.47616730546524805 1.6203288748913365e-06 5.790396828633448 -0.4913880482467392 NSTWSGESK ddPTM_PC-9_Lapatinib_30min_R1 2 NSTWSGESK 9 0 P19338 P19338 NCL Nucleolin 0 ; 117.52 0.0085384 28726000.0 34529.0 32833.0 33207.0 33336.0 34128.0 28903.0 38334.0 31235.0 29489.0 28287.0 False True 34036.6101281569 32756.977205753527 30476.84864272687 35787.64064563601 32120.658138229595 27666.886066183757 40318.74695029747 32686.292128973604 26167.638287063455 33176.37025994175 1.025929294298172 0.9873586817695179 0.918631194550105 1.0787087425548538 0.9681787937185262 0.8339334848691893 1.2152850548264968 0.9852280967710357 0.7887432555772723 1.0 15.017868432979057 -8.029876356886074 24.47951599675964 0.8919095714258227 1.0025499840569778 0.1443684886991864 0.10526909797043389 1014.3913287585132 831145.0756815652 0.06900075672072749 0.026174465331043745 9.335200349934091e-09 8.029876356886074 0.1106404126311551 NSVHEQEAINS(ph)DPELSNCENFQK ddPTM_PC-9_AZD4547_30min_R2 2 NSVHEQEAINSDPELSNCENFQK 23 0 Q8IX90;Q8IX90-3 Q8IX90 SKA3 Spindle and kinetochore-associated protein 3 1 NSVHEQEAINS(1)DPELSNCENFQK;NSVHEQEAINS(1)DPELSNCENFQK 180.21 8.2475e-15 16851200.0 16242.7 12961.4 64026.0 113704.0 78566.0 73972.0 42974.0 78456.0 46224.0 71819.0 True False 21407.540730852048 17150.91907600841 63176.97340615481 87491.29950928829 67658.46704787565 69346.51914628605 46798.60274833088 66332.42793952585 48667.30627183366 69304.63867000227 0.3088904457432524 0.24747144498759202 0.9115836200658275 1.2624162132333274 0.9762473096502968 1.0006042954279468 0.6752593137548111 0.9571138269022834 0.7022229277258861 1.0 16.080664297023688 -5.270606797428607 8.773365299610466 0.9406122271340455 0.27744422139508806 0.740648098711465 0.15561322044194534 0.0743286889999916 57.57942815327612 0.04263825886855155 0.09566388891993512 5.362819780331763e-06 5.270606797428607 -0.6631680057389574 NSVHEQEAINS(ph)DPELSNCENFQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NSVHEQEAINSDPELSNCENFQK 23 0 Q8IX90;Q8IX90-3 Q8IX90 SKA3 Spindle and kinetochore-associated protein 3 1 NSVHEQEAINS(1)DPELSNCENFQK 141.69 1.2855e-11 0.0 3246.1 3987.4 7949.8 8403.0 11008.0 9072.7 8265.5 8441.6 9809.7 5565.7 True False 3795.600616602552 4383.242720191439 8139.353381784394 7932.207152893576 8851.061421589191 8596.911640424463 7482.532002962138 8220.01694461453 9953.148304370892 6574.7173519430435 0.5773024775705116 0.666681544704891 1.2379776872657422 1.2064712029862925 1.3462269095071309 1.3075712886552904 1.13807660503471 1.2502464371620854 1.513851892268709 1.0 12.682713158730127 -5.241781244919812 3.990661514830035 1.2623975151503732 0.5964307268873204 0.7976568261566368 0.12678294886924915 0.08275820737634698 3.069512391796849 0.03216751211013689 0.08765769034735962 5.730846222750756e-06 5.241781244919812 -0.6659667882630529 NSVHEQEAINS(ph)DPELSNCENFQK ddPTM_PC-9_Lapatinib_30min_R1 3 NSVHEQEAINSDPELSNCENFQK 23 0 Q8IX90;Q8IX90-3 Q8IX90 SKA3 Spindle and kinetochore-associated protein 3 1 NSVHEQEAINS(0.999)DPELS(0.001)NCENFQK;NSVHEQEAINS(1)DPELSNCENFQK;NSVHEQEAINS(1)DPELSNCENFQK 179.54 1.5841999999999997e-42 15151100.0 39076.0 37021.1 92186.0 44443.0 69663.0 78644.0 47802.0 61261.0 93233.0 50682.0 True False 38518.76907433924 36935.37991751961 84606.82292825065 47711.48647750184 65565.55930272756 75280.57944811817 50276.95366301767 64107.40970427568 82732.11775298542 59442.31617047999 0.6480024931038653 0.6213650863063495 1.423343307915511 0.8026518741407344 1.1030115164874492 1.2664476133839433 0.8458108112547945 1.0784810188152198 1.391805082354303 1.0 15.859202711148757 -5.233176881322175 24.49115292220679 1.1011091598230005 0.6346835058434778 0.4900718720481848 0.1951981828639667 462.85511849409744 401089.68877691205 0.0478906228329739 0.12664204043124055 5.84551956822997e-06 5.233176881322175 -0.46642565397952274 NSVLSDPGLDS(ph)PRTS(ph)PVIMAR ddPTM_PC-9_AZD4547_30min_R2 2 NSVLSDPGLDSPRTSPVIMAR 21 1 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 2 NS(0.008)VLS(0.287)DPGLDS(0.705)PRT(0.226)S(0.774)PVIMAR;NS(0.003)VLS(0.314)DPGLDS(0.679)PRT(0.401)S(0.603)PVIMAR 76.118 0.0023434999999999997 9341000.0 19328.3 23492.0 21666.5 39108.0 30161.0 28783.0 25424.0 25144.0 23072.0 25968.0 True False 25474.297346385025 31085.329588901626 21379.1880533604 30092.25481257689 25973.665766756385 26983.19445989767 27686.68674718586 21258.572551639616 24291.538817578457 25058.86822404405 1.016578127895751 1.2404921607383357 0.8531585649525469 1.2008624868262523 1.0365059401140306 1.0767922245589376 1.1048658103649076 0.8483452788678604 0.9693789280662988 1.0 14.613033636809737 -7.747526503522279 24.999993209517896 0.9316465649508594 1.0767529895839332 0.25887907360758466 0.10548667238606402 273.5672547239432 491573.8897613531 0.04657612460414645 0.0267161753453174 1.7884363835582266e-08 7.747526503522279 0.14510642463307377 NSVQT(ph)PVENSTNSQHQVK ddPTM_PC-9_AZD4547_30min_R2 1 NSVQTPVENSTNSQHQVK 18 0 Q9UHI6;E9PJ60 Q9UHI6 DDX20 Probable ATP-dependent RNA helicase DDX20 1 NS(0.023)VQT(0.977)PVENSTNSQHQVK 114.76 0.0025565 0.0 3201.7 4183.8 6740.1 17181.0 12609.0 11816.0 6136.4 12862.0 7607.1 10788.0 True False 4219.774000502935 5536.131531331801 6650.721870096897 13220.185893803913 10858.45799718283 11077.14365209154 6682.527712218031 10874.473439356849 8009.195775797552 10410.315403611645 0.40534545178515646 0.531792872424514 0.6388588253329545 1.2699121382256529 1.0430479362244598 1.0640545672851134 0.6419140490113936 1.0445863566808142 0.7693518846719021 1.0 13.345726158497369 -5.570881526132467 7.332085961242447 0.9706289257033655 0.4964584944168967 0.6234688821241885 0.16376956985741062 0.1368477004267535 17.153055979253143 0.04588529501235178 0.080279116795578 2.686077097242751e-06 5.570881526132467 -0.47417043128646874 NSWDS(ph)PAFSNDVIR ddPTM_PC-9_AZD4547_30min_R2 1 NSWDSPAFSNDVIR 14 0 A0A0C4DGT3;A0A3B3IU98;Q6DN90-2;A0A2R8Y7T6;A0A3B3IRZ4;Q6DN90;Q6DN90-3;A0A2R8Y695 A0A0C4DGT3;A0A2R8Y7T6 IQSEC1 IQ motif and SEC7 domain-containing protein 1 1 NS(0.382)WDS(0.616)PAFS(0.002)NDVIR 110.84 0.00045615 19680000.0 9950.6 8678.0 10233.0 12024.0 12939.0 7622.8 8348.6 13411.0 10722.0 10472.0 True False 13114.683814662378 11482.993792460764 10097.30373387658 9252.052568948153 11142.643193397462 7146.145110965076 9091.609226618777 11338.638104121812 11288.743030603167 10105.378467428729 1.2977924435916108 1.1363249609574062 0.9992009469434346 0.9155572548587879 1.102644817243808 0.7071625406211414 0.8996802302776196 1.12203992563644 1.117102448660247 1.0 13.302835734207006 -4.949119563506333 1.9060616208538963 0.9742769313065788 1.3401039613032477 0.41726826933320293 0.11838507172742176 0.5760774394668013 2.907594451664046 0.034707736624509516 0.3357337327206757 1.1242954070434992e-05 4.949119563506333 0.36582702999666894 NSWDS(ph)PAFSNDVIR ddPTM_PC-9_Lapatinib_30min_R1 1 NSWDSPAFSNDVIR 14 0 A0A0C4DGT3;A0A3B3IU98;Q6DN90-2;A0A2R8Y7T6;A0A3B3IRZ4;Q6DN90;Q6DN90-3;A0A2R8Y695 A0A0C4DGT3;A0A2R8Y7T6 IQSEC1 IQ motif and SEC7 domain-containing protein 1 1 NS(0.162)WDS(0.832)PAFS(0.006)NDVIR 176.17 0.00010579 17759000.0 23326.0 21077.0 21721.0 18238.0 21817.0 17462.0 16948.0 15192.0 16220.0 15510.0 True False 22993.366962535492 21028.19750146703 19935.183225484707 19579.283360184472 20533.766953872335 16715.190965910147 17825.484512799114 15897.875781122686 14393.132795827909 18190.882834224078 1.2640050058085188 1.1559745446716236 1.0958887156361057 1.0763239771600461 1.1287944153672622 0.9188773913964426 0.9799131067604092 0.8739474563165588 0.7912278324803932 1.0 14.150927940661447 -6.435607645728243 0.65288141589942 0.8751713909997447 1.214472536556321 0.7333978598356421 0.07003424191332867 0.4219362934581882 0.39510769407408797 0.04902602454854999 0.07489567530444703 3.6676877460043163e-07 6.435607645728243 0.3393011455565762 NSYATTENKT(ph)LPR ddPTM_PC-9_AZD4547_30min_R2 1 NSYATTENKTLPR 13 1 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;I3L0Y9 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 NSYATT(0.002)ENKT(0.997)LPR 59.15 0.045092 243290000.0 85207.0 74222.0 93301.0 140180.0 114540.0 100320.0 92537.0 92272.0 90934.0 100250.0 True False 112301.05358429991 98212.8100096823 92063.76777820966 107863.66675941048 98638.09810431582 94046.97454111557 100772.61373207756 78013.48259962165 95740.58559455954 96740.27801372524 1.1608510528403375 1.0152214984925736 0.9516591193292613 1.114981980350595 1.0196176828261887 0.9721594404325823 1.0416820770122268 0.8064219392521625 0.989666223421191 1.0 16.561829063378774 -7.102079160280651 1.3567064950749348 0.9341557871899171 1.0497388762475965 0.25298690888182473 0.07808257249998286 0.5834383221838304 2.1481615993147405 0.04348898005297728 0.029079193773918564 7.905345215449243e-08 7.102079160280651 0.11558308905767944 NSYNNSQAPS(ph)PGLGSK ddPTM_PC-9_AZD4547_30min_R2 2 NSYNNSQAPSPGLGSK 16 0 Q9UHB7 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 NSYNNSQAPS(1)PGLGSK;NSYNNS(0.001)QAPS(0.998)PGLGS(0.001)K 247.28 4.5165999999999995e-47 63693000.0 137749.0 143233.0 172539.0 233776.0 199852.0 173334.0 181358.0 167777.0 160438.0 165933.0 True False 181550.31664280803 189530.26617602372 170251.02012501992 179882.55500319586 172105.99949662806 162495.39757884532 197498.5106630005 141850.91978191343 168918.42513933138 160123.7361760746 1.1338126437617744 1.1836487875077637 1.0632466128432652 1.1233971883181275 1.0748312749046625 1.0148114293321435 1.2334118312467304 0.8858831499280776 1.0549243302291298 1.0 17.288827658151554 -6.485181842499334 0.3064069996946814 0.9828071965769188 1.1897864204377218 0.24894268344850012 0.08140004053447769 3.8359532876580573 0.658083989813405 0.10483037682412374 0.2817494428196682 3.272036634574574e-07 6.485181842499334 0.20697922386080292 NSYNNSQAPS(ph)PGLGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NSYNNSQAPSPGLGSK 16 0 Q9UHB7 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 NSYNNS(0.002)QAPS(0.998)PGLGSK;NSYNNS(0.002)QAPS(0.983)PGLGS(0.015)K;NSYNNSQAPS(0.998)PGLGS(0.002)K;NSYNNSQAPS(1)PGLGSK 222.93 1.6334e-28 56532600.0 335085.0 363675.0 292182.0 412406.0 403760.0 358210.0 425795.0 373077.0 316269.0 302055.0 True False 391808.27226957574 399778.250555656 299148.7269864052 389300.2288582921 324646.1264154122 339424.83700733463 385460.6151111564 363284.12405775714 320893.83580283535 356815.1804339347 1.098070636437286 1.1204070691988846 0.8383856500236356 1.0910416658418267 0.9098439310250177 0.9512623218399757 1.080280874379798 1.0181296760299137 0.8993278688776238 1.0 18.444817469377973 -5.164932060613449 24.999999974693004 0.9791056113869366 1.1092415668094318 0.3400022149442887 0.07530887671358136 55.24410617574309 14306.142538415495 0.01840691491382526 0.0487001611495062 6.840186442023336e-06 5.164932060613449 0.13013595542249512 NSYNNSQAPS(ph)PGLGSK ddPTM_PC-9_Lapatinib_30min_R1 2 NSYNNSQAPSPGLGSK 16 0 Q9UHB7 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 NSYNNS(0.137)QAPS(0.863)PGLGSK;NSYNNSQAPS(1)PGLGSK 195.77 7.9532e-12 64982000.0 201897.0 176537.0 170569.0 166085.0 169476.0 175826.0 163659.0 164898.0 153123.0 130124.0 True False 199017.91175662502 176128.239422901 156545.47523538055 178299.44494331843 159507.75488263567 168306.3318504246 172132.46223036275 172559.76306974524 135876.67528332653 152615.76002066905 1.3040456092455435 1.1540632461486784 1.0257490786939651 1.168289860229186 1.045159129443992 1.1028109536500723 1.1278813027373484 1.1306811501405565 0.8903187669800582 1.0 17.219544425663308 -1.8428174843961336 0.9723893878000731 1.0682138902266032 98.65871373459746 0.4827776481388961 0.07650903226687251 606.2711830677966 1.9276076846324293 0.02397839826842312 131053.26127800452 0.014360928356371322 1.8428174843961336 97.59049984437085 NSYVAGQYDDAASYQR ddPTM_PC-9_AZD4547_30min_R2 2 NSYVAGQYDDAASYQR 16 0 P11413;P11413-2;P11413-3;E7EUI8;E7EM57;E9PD92 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ; 263.15 3.6170999999999993e-68 29951000.0 31736.0 33992.0 32871.0 59761.0 40273.0 34886.0 31809.0 46735.0 32253.0 41328.0 False True 41827.38785019246 44979.24925021047 32435.10906247016 45984.0247482461 34681.78911258181 32704.572905117235 34639.939377801864 39513.17961346152 33957.82773419547 39881.119299264166 1.0488017534393577 1.12783317119789 0.8132948531128266 1.1530274364464623 0.8696292812729987 0.8200515301414987 0.8685799191809793 0.9907740882836898 0.8514762958225701 1.0 15.283418280379765 -5.274412676342727 0.808516858985273 0.904319497720586 1.1234400126733752 0.21968388019164842 0.10635192721623107 2.0807064778430715 1.676593751759132 0.04324520587697302 0.3604412817972433 5.3160287823249295e-06 5.274412676342727 0.21912051495278928 NSYVAGQYDDAASYQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NSYVAGQYDDAASYQR 16 0 P11413;P11413-2;P11413-3;E7EUI8;E7EM57;E9PD92 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ;; 174.24 7.417700000000001e-21 14199800.0 48344.8 48869.7 42761.7 54775.0 59376.0 48682.0 53300.0 51379.0 43750.5 43817.2 False True 56528.619786675445 53721.16084740421 43781.30110265033 51706.134332946014 47741.69903418241 46129.03022023693 48251.03814141696 50030.35569055037 44390.26829468574 51760.91150323568 1.0921102072003064 1.0378712292198717 0.8458371352272935 0.9989417270929195 0.9223504310042527 0.8911943178850957 0.9321906577785186 0.9665663574611292 0.857602136544887 1.0 15.659575402784412 -5.070368528125502 5.753939137197393 0.9271873229517769 1.080283122884443 0.5597906611418996 0.05001003419969059 0.1275915015303511 7.738171491454176 0.011943298550383936 0.03395431095133008 8.504160965887522e-06 5.070368528125502 0.1530957999326661 NSYVAGQYDDAASYQR ddPTM_PC-9_Lapatinib_30min_R1 4 NSYVAGQYDDAASYQR 16 0 P11413;P11413-2;P11413-3;E7EUI8;E7EM57;E9PD92 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ;;; 316.12 1.8098999999999993e-146 64013500.0 121868.0 109216.1 109702.0 105586.0 107029.0 107849.5 110725.0 86354.8 97484.1 101002.4 False True 120130.1399721457 108963.21683066696 100682.72502196605 113351.14666457076 100733.76464711023 103237.02829446383 116457.79871841401 90367.15926169646 86504.41410491792 118460.53026276168 1.014094227889075 0.9198271912929279 0.8499263408549496 0.9568684726730701 0.8503571985003693 0.8714888247205206 0.9830936807398605 0.7628461485125022 0.7302382820086933 1.0 16.85404692360693 -1.5228787453315014 0.6282593259376446 0.8630090971300117 11.79219288552768 0.19663698176993483 0.08340398300422186 329.317360197608 2.30518852868387 0.03671151540251183 4979.600070871803 0.02999999999646573 1.5228787453315014 10.929183788397667 NT(ph)IDT(ph)KDYS(ph)T(ph)HRLYQVLEGENK ddPTM_PC-9_AZD4547_30min_R2 1 NTIDTKDYSTHRLYQVLEGENK 22 2 A0A5F9ZHQ7;Q68CZ6-2;Q68CZ6 A0A5F9ZHQ7 HAUS3 HAUS augmin-like complex subunit 3 4 NT(0.95)IDT(0.737)KDY(0.52)S(0.891)T(0.891)HRLY(0.012)QVLEGENK 75.682 0.0030249 0.0 693.01 1189.1 1111.5 2604.2 1200.6 1332.3 1132.8 1355.1 2412.6 3321.3 True False 913.3727644965297 1573.4533208821258 1096.7607837588016 2003.8419244889221 1033.9174138645174 1248.9910703860496 1233.6170054756187 1145.7004321001764 2540.125110579482 3205.022297925041 0.28498171918736886 0.49093365805935046 0.34220067188576314 0.6252193395928093 0.32259289257796564 0.38969809077292755 0.38490122401777765 0.3574703467248614 0.7925452226101456 1.0 11.646118678633709 -8.421755970301072 3.287113449754152 0.9947746671519908 0.40480742106499096 0.8260366557988451 0.09323332834279474 0.0844172194038666 1.7002128637698142 0.08591448866900495 0.02290494314853626 3.78655291036787e-09 8.421755970301072 -0.5899672460869998 down NT(ph)VLATWQPYT(ph)TSK ddPTM_PC-9_AZD4547_30min_R2 1 NTVLATWQPYTTSK 14 0 F8WAE5;Q9BY44-3;Q9BY44;H7C5Q3;C9IZE1 F8WAE5 EIF2A Eukaryotic translation initiation factor 2A;Eukaryotic translation initiation factor 2A, N-terminally processed 2 NT(1)VLAT(0.019)WQPY(0.244)T(0.368)T(0.368)S(0.001)K 85.29 0.035448 71322000.0 16580.0 16943.0 23313.0 30718.0 27893.0 23815.0 18946.0 27276.0 21702.0 24650.0 True False 21852.09511457621 22419.493411576717 23003.854387556403 23636.43968836905 24020.5384182267 22325.84428525389 20632.157296734702 23061.120940125762 22849.123414488895 23787.01100287605 0.9186566194438681 0.9425099021001845 0.9670762915431049 0.99367001955442 1.0098174342006407 0.9385729162253512 0.8673707383512834 0.9694837631065744 0.9605714400908228 1.0 14.5378863784144 -5.3687302868926245 0.00315474638550696 1.9008341336624643 1.36239317322849e-07 0.062325502133738886 0.039102224176018024 274211.03769175505 165.39340280402826 48902.56293351846 50761.48652563461 4.278285011562563e-06 5.3687302868926245 -1.900833997423147 NTAPVNT(ph)VMDSPVHLEPSSQVGVIQNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NTAPVNTVMDSPVHLEPSSQVGVIQNK 27 0 Q6UB98-2;Q6UB98 Q6UB98-2 ANKRD12 Ankyrin repeat domain-containing protein 12 1 NT(0.003)APVNT(0.499)VMDS(0.498)PVHLEPSSQVGVIQNK 84.68 6.1632e-05 0.0 1831.9 3227.1 4029.5 4571.0 6487.9 5146.9 4100.0 3288.8 5288.6 2831.9 True False 2142.0044883257515 3547.4651608390927 4125.578561963847 4314.90168938195 5216.642568779842 4876.98750340038 3711.6183185705386 3202.4724847716384 5365.935769951779 3345.3010526919365 0.6403024584594854 1.060432261540251 1.2332458266032673 1.2898395753977907 1.5593940535133757 1.4578620657999997 1.109502032883955 0.9573047191655994 1.6040217862107966 1.0 11.707920333400864 -4.726477180773596 1.6498966290355703 1.2900740024562856 0.3440494698461502 0.4698812802453397 0.206850337618032 1.036898367915421 2.4962661388535974 0.0589061717139407 1.6466283683939533 1.8772530526861238e-05 4.726477180773596 -0.9460245326101353 NTAS(ph)LNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NTASLNSR 8 0 C9JXI9;C9JSG7;C9JJM9;C9JD81;C9J3W7;C9JBN7;C9JEW7;C9J718;C9JF32;A0A0C4DG23;A0A3B3ITR4;O00522-3;O00522 C9JXI9 KRIT1 Krev interaction trapped protein 1 1 NT(0.003)AS(0.996)LNS(0.001)R;NT(0.015)AS(0.985)LNSR 73.9 0.028689999999999997 53754000.0 75537.0 78540.0 110927.0 112882.0 119494.0 83188.0 123618.0 109094.0 107140.0 78977.0 True False 88323.92217624428 86336.93214722267 113571.92037299016 106557.58750838164 96080.00849485646 78825.47483589558 111908.00812318343 106230.39809464774 108706.71981103403 93294.90491841202 0.9467175324685206 0.9254195845177803 1.2173432243948448 1.1421587020381023 1.0298526867987063 0.8449065348727222 1.1995082498990581 1.1386516572105199 1.1651946042080208 1.0 16.50951067338473 NTAS(ph)LNSR ddPTM_PC-9_Lapatinib_30min_R1 1 NTASLNSR 8 0 C9JXI9;C9JSG7;C9JJM9;C9JD81;C9J3W7;C9JBN7;C9JEW7;C9J718;C9JF32;A0A0C4DG23;A0A3B3ITR4;O00522-3;O00522 C9JXI9 KRIT1 Krev interaction trapped protein 1 1 NT(0.011)AS(0.978)LNS(0.011)R 96.756 0.0060224 31695000.0 174540.0 121370.0 128150.0 134530.0 148070.0 149910.0 106220.0 107140.0 156820.0 104020.0 True False 172051.02759328388 121088.97522195031 117614.00167330557 144423.78497892423 139360.81371682053 143498.69875727818 111719.5518615485 112118.11553379991 139157.2802121907 121999.71840206256 1.4102575796631933 0.9925348747354417 0.9640514192475149 1.183804248653762 1.1423043884211495 1.1762215572036283 0.9157361453357236 0.919003068222692 1.1406360771553885 1.0 16.896518292221558 -7.254976410023102 24.97731096015731 0.9870940771719959 1.1313735079224736 0.24652613351572206 0.12782763606019254 808.687838992582 3125328.0286925253 0.05008235588943999 0.03781883756887794 5.5593445365855936e-08 7.254976410023102 0.14427943075047767 NTASLNS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 NTASLNSR 8 0 C9JXI9;C9JSG7;C9JJM9;C9JD81;C9J3W7;C9JBN7;C9JEW7;C9J718;C9JF32;A0A0C4DG23;A0A3B3ITR4;O00522-3;O00522 C9JXI9 KRIT1 Krev interaction trapped protein 1 1 NT(0.003)AS(0.049)LNS(0.948)R 90.149 0.009692000000000001 24656000.0 106670.0 67596.0 83260.0 77131.0 69118.0 79080.0 52022.0 78159.0 69790.0 58532.0 True False 105148.8662391176 67439.48561508593 76414.68419289442 82803.4710414732 65052.615131216415 75697.93274448375 54715.44461439909 81790.55247345754 61929.51527871944 68649.1782110125 1.531684267449103 0.9823786296143524 1.1131187027179328 1.2061829900855259 0.9476095246363905 1.1026779157035926 0.7970298558595389 1.1914279909083738 0.9021159013493462 1.0 16.066954829739842 -4.757828238374011 24.999904760458403 1.0339272164933795 1.5316849700748083 0.6036914208321742 0.12256842167939387 69.51210499960413 481159.81626612623 0.029028754077061777 0.2089922083850202 1.7465127547349557e-05 4.757828238374011 0.4977577535814288 NTASQNS(ph)ILEEGETK ddPTM_PC-9_AZD4547_30min_R2 5 NTASQNSILEEGETK 15 0 Q15398-1;Q15398;Q15398-3 Q15398-1 DLGAP5 Disks large-associated protein 5 1 NTASQNS(1)ILEEGETK;NTASQNS(1)ILEEGETK;NTAS(0.001)QNS(0.998)ILEEGETK;NTASQNS(1)ILEEGETK;NTASQNS(1)ILEEGETK 181.86 1.1749e-28 5295700.0 139301.5 126815.3 149214.2 172952.1 153443.3 188511.5 150776.1 187170.0 162128.0 159619.0 True False 183596.47934880244 167805.86571664558 147235.5222131736 133080.6654283083 132140.34641915496 176723.846104541 164194.88080799126 158247.1772387207 170697.7550891279 154030.78739424242 1.1919466390760343 1.089430681719141 0.9558837210662546 0.8639874383533975 0.8578826912112135 1.1473280705383633 1.0659874145013217 1.0273736823384951 1.1082054307248739 1.0 17.232859217446098 -9.16043047477006 15.302471475698331 0.9999999999999998 1.0274103237731347 0.005556107097468677 0.1067135160127201 0.0 0.0 0.11248616061982696 0.02728190127386708 6.911455644929468e-10 9.16043047477006 0.027410323773134904 NTASQNS(ph)ILEEGETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NTASQNSILEEGETK 15 0 Q15398-1;Q15398;Q15398-3 Q15398-1 DLGAP5 Disks large-associated protein 5 1 NTASQNS(1)ILEEGETK;NTAS(0.003)QNS(0.997)ILEEGETK 166.36 0.00014197 6011800.0 29680.8 37903.0 28329.9 34156.0 32984.0 23699.6 31818.0 27717.8 22377.4 22904.4 True False 34705.17321747853 41665.75934779963 29005.39225774405 32242.350055246072 26521.021977625183 22456.751255238632 28803.96869762861 26990.237119436682 22704.627141118403 27056.78640886938 1.28267905482308 1.539937475137156 1.072019116366159 1.1916548243392584 0.9801985193973898 0.8299859013514322 1.0645746417315285 0.9975403845664805 0.8391472216255397 1.0 14.72370287713056 -5.660008947620861 1.2184150911195197 0.9516881890708516 1.4201503617817297 0.6778875635103296 0.11478907728477528 0.2955471234732403 0.8323242592227613 0.03851605769880549 0.11779649859977703 2.1877165507084413e-06 5.660008947620861 0.4684621727108781 NTASQNS(ph)ILEEGETK ddPTM_PC-9_Lapatinib_30min_R1 1 NTASQNSILEEGETK 15 0 Q15398-1;Q15398;Q15398-3 Q15398-1 DLGAP5 Disks large-associated protein 5 1 NTAS(0.001)QNS(0.999)ILEEGETK 227.46 1.9409e-24 4955100.0 47631.0 59427.0 63066.0 58268.0 58029.0 53907.0 50233.0 46261.0 60286.0 50125.0 True False 46951.77320554434 59289.400432684015 57880.956921800025 62553.223096349895 54615.84830940356 51601.52327335464 52833.81894804333 48410.45494408352 53495.95584027631 58789.0394626358 0.7986484153289356 1.0085111268124431 0.9845535400963147 1.0640286636441214 0.9290141293108799 0.8777405404990621 0.8987018571994632 0.823460552963303 0.909964788151989 1.0 15.843259585855 -6.519843093461755 22.213820065407642 0.8921399538286017 0.9720832889198832 0.1202590603783874 0.07545520387024317 48.359055824149706 353890.2932262356 0.02427419495604589 0.02481738752627841 3.021042997862343e-07 6.519843093461755 0.07994333509128149 NTDDDRPPR ddPTM_PC-9_AZD4547_30min_R2 1 NTDDDRPPR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 80.688 0.023752000000000002 2398900.0 19099.0 20170.0 20870.0 24338.0 21030.0 26448.0 20696.0 25503.0 20646.0 25132.0 False True 25172.084716121306 26689.558054152298 20593.25016378425 18727.25011835165 18110.347504223544 24794.202379021415 22537.903906535485 21562.097350638902 21737.30541035563 24252.136329585457 1.0379326742202746 1.1005033821120906 0.8491313871867985 0.7721897099640688 0.7467526678105683 1.0223512700930468 0.9293162301352083 0.8890803291557888 0.8963047673387043 1.0 14.56582421700787 -5.261284893871063 24.999999311770537 0.8812524722467219 1.0692180401191245 0.4280840450536867 0.08341583731598641 12.475221299918806 2018411.1948968468 0.022994832647893537 0.053557051888322264 5.479174173525358e-06 5.261284893871063 0.1879655678724026 NTDDDRPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NTDDDRPPR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 76.17 0.032285 2226100.0 14175.0 18886.0 16363.0 18754.0 20369.0 11725.0 15988.0 14274.0 13062.0 11727.0 False True 16574.547530988322 20760.877266774234 16753.155977023078 17703.274181288343 16377.840670089949 11110.120359317156 14473.500896903844 13899.32262455315 13253.007039123793 13853.012269119075 1.1964580128132891 1.4986543622035235 1.2093511253410898 1.2779368008467165 1.1822584396751876 0.8020003262455536 1.0447908812704911 1.0033429809007899 0.9566877428288427 1.0 13.757912096849244 -6.564448191191311 5.467093086267297 0.9669023591086718 1.296374458168457 0.7262184812543031 0.09752625838143057 0.0986717329687955 7.182979048463644 0.03203293381134628 0.03243693021694603 2.726162934931841e-07 6.564448191191311 0.32947209905978525 NTDDDRPPR ddPTM_PC-9_Lapatinib_30min_R1 2 NTDDDRPPR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 ; 85.86200000000001 0.015694999999999997 4944800.0 29609.0 36934.0 39100.0 36893.0 35647.0 31969.0 42454.0 38468.0 37149.0 36937.0 False True 29186.770230374423 36848.48159221817 35885.34893036471 39606.2342914402 33550.31354469848 30601.760393378845 44652.060390982624 40255.36371433832 32964.88842368751 43321.51123454121 0.6737246554571521 0.8505816288984409 0.8283494252100909 0.9142394427796707 0.77444928832372 0.7063871855185738 1.0307133596803182 0.929223440438103 0.7609357911181054 1.0 15.402795950578554 -1.587586357680062 0.04090550717375288 1.3651589925165957 1.0908603923269343e-11 0.2681933880694797 0.09801195366754434 1093.3468988122268 3.4526172662567167 31.369188821302068 103.05692476447975 0.02584720827302599 1.587586357680062 -1.365158992505687 NTDEMVELR ddPTM_PC-9_AZD4547_30min_R2 1 NTDEMVELR 9 0 P61978;P61978-2;P61978-3;Q5T6W2;S4R457 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 87.806 0.031889999999999995 0.0 16588.0 16354.0 21237.0 28112.0 27235.0 26908.0 19238.0 32680.0 22546.0 21143.0 False True 21862.638948165884 21640.11068009948 20955.383503990717 21631.2127260704 23453.890360319947 25225.438506303257 20950.14473105574 27630.056911691965 23737.73553142874 20402.790005428342 1.071551436952943 1.0606446801805995 1.0270842124246415 1.0602085656086853 1.1495432906028946 1.2363720108667395 1.0268274449465868 1.354229343356509 1.163455366894092 1.0 14.316478828401731 -6.296534030308977 4.039305137400967 1.1720746588283095 1.0522585368339847 0.20331619359374753 0.09449291503051964 0.3054440263505342 11.171061425457884 0.028688100089624375 0.03410666473271658 5.052030568486059e-07 6.296534030308977 -0.11981612199432479 NTDEMVELR ddPTM_PC-9_Lapatinib_30min_R1 4 NTDEMVELR 9 0 P61978;P61978-2;P61978-3;Q5T6W2;S4R457 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 ;;; 136.52 0.0032229999999999997 19524900.0 110594.0 128983.0 145182.0 113333.6 126140.0 130265.0 122861.0 115707.0 124044.8 114473.0 False True 109016.90927954408 128684.34778819219 133245.6963787263 121668.53101380635 118720.69320078159 124693.8696125463 129222.14141651013 121083.16962917056 110073.56837434741 134259.50552431546 0.8119865245578478 0.9584747633744742 0.9924488836627993 0.9062191204910345 0.884262851536276 0.9287526356185131 0.9624803913277259 0.9018591954164574 0.8198567985520564 1.0 17.034664708549336 NTDQASMPDNTAAQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NTDQASMPDNTAAQK 15 0 P35579;P35579-2;A0A494C024;P35749-4;P35749-3;P35749;P35749-2 P35579;P35749-4 MYH9;MYH11 Myosin-9;Myosin-11 0 108.23 0.0049787 0.0 5645.2 5203.3 5803.9 7649.4 5422.3 4786.8 6473.2 6732.0 5495.2 5118.9 False True 6600.82086221766 5719.849236588284 5942.286987413318 7220.828917689406 4359.839239306239 4535.771781320203 5860.011634090437 6555.292133143603 5575.556904102973 6046.916048809897 1.0916012077787616 0.945911798744753 0.9826971202259089 1.1941341436533668 0.721002111508445 0.7500967013115547 0.9690909526094306 1.0840719600256001 0.9220496628525722 1.0 12.561983834412858 -6.252732648631694 24.9823404656988 0.9071096863287416 1.0408315351254804 0.2623204848880323 0.11906590132953368 1096.5544608047812 3146357.7528515197 0.03858506663269061 0.0490181382107072 5.588140944253002e-07 6.252732648631694 0.13372184879673887 NTDQASMPDNTAAQK ddPTM_PC-9_Lapatinib_30min_R1 3 NTDQASMPDNTAAQK 15 0 P35579;P35579-2;A0A494C024;P35749-4;P35749-3;P35749;P35749-2 P35579;P35749-4 MYH9;MYH11 Myosin-9;Myosin-11 0 ;; 200.19 2.0644e-09 8055300.0 34196.8 32525.7 35624.7 33653.7 31586.0 26365.899999999998 30305.1 28292.2 31919.0 30170.1 False True 33709.14736107493 32450.38874002307 32695.774681318788 36128.705363452136 29728.173580465293 25238.2919189148 31874.149794006877 29606.75889775403 28323.946098029046 35384.96158586869 0.9526404961405127 0.9170672309838661 0.9240019832147041 1.0210186402429349 0.8401358161241445 0.7132490975769195 0.9007823766222799 0.8367045651839216 0.8004515146722804 1.0 15.110848732650247 -6.329670905848132 10.59072503072618 0.8361284548389387 0.9489075150430366 0.31974973137595086 0.07366737831715828 0.7651856040215398 116.64874500845774 0.022120217166058925 0.025084662509190028 4.6808971000016587e-07 6.329670905848132 0.11277906020409789 NTDT(ph)Y(ph)IPTIICS(ph)HEDKEDLEASNR ddPTM_PC-9_Lapatinib_30min_R1 1 NTDTYIPTIICSHEDKEDLEASNR 24 1 Q16821 Q16821 PPP1R3A Protein phosphatase 1 regulatory subunit 3A 3 NT(0.389)DT(0.685)Y(0.636)IPT(0.292)IICS(0.998)HEDKEDLEASNR 52.464 0.030025 0.0 2849.2 3457.9 4291.5 3636.7 5584.8 5542.2 4444.5 5908.9 6994.0 5892.2 True False 2808.569885520713 3449.8934450027427 3938.6694356690614 3904.155049675564 5256.313044139254 5305.1730254992135 4674.61446289448 6183.449065499989 6206.262069914945 6910.658919137018 0.40641130149589827 0.49921338693902073 0.5699412287245267 0.5649468589549639 0.7606095316878476 0.7676797665137419 0.6764354191970788 0.8947698241012537 0.8980709571309539 1.0 12.75460756026114 -5.262923135622452 0.2259318929855154 1.0431854404623357 1.7448341046040428e-23 0.918303856312657 0.05250916041352751 2.5320297630604536 0.1402473841512823 0.10031632044562423 0.741815781916937 5.4585446156051695e-06 5.262923135622452 -1.0431854404623357 down NTDVAQS(ph)PEAPK ddPTM_PC-9_AZD4547_30min_R2 4 NTDVAQSPEAPK 12 0 Q9P2E9;A0A087WVV2;Q9P2E9-3;V9GY78 Q9P2E9;V9GY78 RRBP1 Ribosome-binding protein 1 1 NT(0.01)DVAQS(0.99)PEAPK;NT(0.002)DVAQS(0.998)PEAPK;NTDVAQS(1)PEAPK;NTDVAQS(1)PEAPK 174.47 0.00013078 98982400.0 504637.0 603439.0 531935.0 442806.0 450821.0 579466.0 561205.0 583720.0 579970.0 466147.0 True False 665101.0688983338 798488.8558571948 524881.1943398447 340723.91798450204 388232.28588690306 543231.8994162888 611151.157801857 493519.48655118694 610626.0301677778 449827.33541410527 1.478569701163337 1.7751007842200524 1.1668503735030817 0.7574548969347005 0.8630695720825889 1.2076453711204467 1.3586349909999114 1.0971309382451364 1.3574675927723319 1.0 18.779011808892 -5.3392302577891275 5.958307053527554 1.0934292630498021 1.6244216965328868 0.542774554224022 0.193514889788294 0.16513061900357434 9.858453550288262 0.055202974705465695 0.11771700751310427 4.578990496942443e-06 5.3392302577891275 0.5309924334830847 NTDVAQS(ph)PEAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NTDVAQSPEAPK 12 0 Q9P2E9;A0A087WVV2;Q9P2E9-3;V9GY78 Q9P2E9;V9GY78 RRBP1 Ribosome-binding protein 1 1 NTDVAQS(1)PEAPK;NTDVAQS(1)PEAPK;NTDVAQS(1)PEAPK;NTDVAQS(1)PEAPK 145.7 5.6141000000000003e-05 112051000.0 576774.0 897269.0 583598.0 553636.0 612135.0 424547.0 602790.0 364711.0 386041.0 389848.0 True False 674410.446394235 986343.9364757629 597513.189627739 522617.5698321301 492191.54099786555 402283.0079477206 545689.3673783242 355137.7226932464 391686.11930717924 460524.35636492906 1.4644403429985322 2.1417845176774177 1.2974627321432206 1.1348315514890968 1.0687633220594368 0.8735325339208404 1.1849305250337479 0.7711594789393242 0.8505220492546522 1.0 18.812917934505137 -5.5583018018245705 2.605051169914163 0.9743933792764505 1.8035842708101344 0.7229705137552509 0.19946562536378729 0.1312104569308572 1.783533795135397 0.054327797623206185 0.11834350717523862 2.7650194981485827e-06 5.5583018018245705 0.8291908915336839 NTDVAQS(ph)PEAPK ddPTM_PC-9_Lapatinib_30min_R1 4 NTDVAQSPEAPK 12 0 Q9P2E9;A0A087WVV2;Q9P2E9-3;V9GY78 Q9P2E9;V9GY78 RRBP1 Ribosome-binding protein 1 1 NTDVAQS(1)PEAPK;NTDVAQS(1)PEAPK;NTDVAQS(1)PEAPK;NTDVAQS(1)PEAPK 125.67 0.00028612 101916800.0 194743.0 280936.0 221422.0 205919.0 275000.0 276348.0 292062.0 287631.0 213143.0 210901.0 True False 191965.9291085079 280285.5099526569 203217.53787363763 221062.97018564653 258825.04067080206 264529.24023865216 307183.5412896586 300995.38630859007 189136.59084470719 247354.95684208223 0.7760747209568308 1.1331307588535549 0.8215624237656856 0.8937074599510808 1.0463709479492769 1.0694317333108243 1.2418734001185692 1.2168560927637009 0.7646363479404896 1.0 17.916223284949467 -6.371768822610504 4.036725652428919 1.0812647798824275 0.9165514063313144 0.18345901621119398 0.1508727928078804 0.39018298384051553 11.04556791114217 0.04804792316439623 0.054981505123678026 4.2484565149119176e-07 6.371768822610504 -0.16471337355111315 NTDVAQS(ph)PEAPKQEAPAK ddPTM_PC-9_AZD4547_30min_R2 3 NTDVAQSPEAPKQEAPAK 18 1 Q9P2E9;A0A087WVV2;Q9P2E9-3;V9GY78 Q9P2E9;V9GY78 RRBP1 Ribosome-binding protein 1 1 NT(0.001)DVAQS(0.999)PEAPKQEAPAK;NT(0.001)DVAQS(0.999)PEAPKQEAPAK;NT(0.001)DVAQS(0.999)PEAPKQEAPAK 82.26700000000001 0.0012973 657185000.0 444560.0 360747.0 433450.0 580770.0 528960.0 514570.0 405770.0 445558.0 417661.0 488860.0 True False 585920.8325775637 477351.41295792157 427702.1697888017 446882.4493070543 455523.03451422305 482393.85655524215 441882.7439193527 376707.2490042737 439737.7077881687 471745.1601974041 1.2420282856370635 1.0118840705396352 0.9066381722068492 0.9472963095584364 0.9656125233454588 1.0225729848577185 0.936697991208738 0.7985397218418492 0.9321509681289751 1.0 18.847648191213203 -4.779064659114959 2.7358473301350057 0.9359553165938725 1.3021242177364993 0.717908472694665 0.05708150181996386 0.2554679757104057 2.567429906552318 0.015862248629651594 0.21593352842651356 1.66316501474937e-05 4.779064659114959 0.3661689011426268 NTDVAQS(ph)PEAPKQEAPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 NTDVAQSPEAPKQEAPAK 18 1 Q9P2E9;A0A087WVV2;Q9P2E9-3;V9GY78 Q9P2E9;V9GY78 RRBP1 Ribosome-binding protein 1 1 NT(0.01)DVAQS(0.99)PEAPKQEAPAK;NTDVAQS(1)PEAPKQEAPAK;NTDVAQS(1)PEAPKQEAPAK;NT(0.057)DVAQS(0.943)PEAPKQEAPAK;NT(0.002)DVAQS(0.998)PEAPKQEAPAK;NTDVAQS(1)PEAPKQEAPAK 99.569 0.00030252 605207000.0 363866.0 333688.0 279880.0 410591.0 417538.0 381250.0 441663.0 373477.0 366665.0 301172.0 True False 425461.3271189144 366814.3393728349 286553.4006508105 387586.91742398235 335724.42622161267 361256.5788477325 399825.48327678436 363673.6244815921 372026.7819629704 355772.09952376015 1.19588165482465 1.031037396872481 0.8054409017300501 1.0894247130194015 0.9436502375285092 1.015415709470512 1.123824728841847 1.022209512686377 1.0456884687162622 1.0 18.440593849974455 -7.021144326247412 24.3692702788425 1.0526155768319083 1.0040636789750708 0.02380788220994612 0.09834666788037229 2049.7401485039154 2362360.7901616395 0.037724186570946935 0.02955174268373506 9.52479580107251e-08 7.021144326247412 -0.048551897856837556 NTDVAQS(ph)PEAPKQEAPAK ddPTM_PC-9_Lapatinib_30min_R1 4 NTDVAQSPEAPKQEAPAK 18 1 Q9P2E9;A0A087WVV2;Q9P2E9-3;V9GY78 Q9P2E9;V9GY78 RRBP1 Ribosome-binding protein 1 1 NT(0.019)DVAQS(0.981)PEAPKQEAPAK;NTDVAQS(1)PEAPKQEAPAK;NT(0.014)DVAQS(0.986)PEAPKQEAPAK;NTDVAQS(1)PEAPKQEAPAK 100.85 0.00026528 777214000.0 567060.0 414766.0 442086.0 404077.0 415102.0 415936.0 387215.0 355505.0 381773.0 313874.0 True False 558973.6204139318 413805.6348101471 405739.39558131003 433794.1705413559 390686.516481932 398147.3868741729 407263.0980424535 372023.0601348099 338773.7044920841 368126.7026891833 1.5184272597738837 1.1240848104396584 1.1021732262760735 1.178382788785678 1.061282742131848 1.0815498684710645 1.1063122970090922 1.0105842836641936 0.9202638711544853 1.0 18.489842876264284 -2.0122771539956936 1.0518165749347397 1.0537799352459298 199.99999999618254 0.8108437106947757 0.06637746787616385 312.0611177792664 1.0682250350332023 0.021689723509172514 148855.971605798 0.009721266430794356 2.0122771539956936 198.9462200609366 NTDVAQS(ph)PEAPKQEAPAKK ddPTM_PC-9_AZD4547_30min_R2 1 NTDVAQSPEAPKQEAPAKK 19 2 Q9P2E9;A0A087WVV2;Q9P2E9-3;V9GY78 Q9P2E9;V9GY78 RRBP1 Ribosome-binding protein 1 1 NT(0.12)DVAQS(0.88)PEAPKQEAPAKK 40.285 0.043737 15859000.0 46211.0 37144.0 38474.0 56001.0 47759.0 52372.0 37026.0 45054.0 38700.0 49882.0 True False 60905.136751488615 49150.071609490944 37963.80962153496 43090.834656825165 41128.487230347724 49097.1705608783 40321.24227113369 38091.93953792439 40745.602992384134 48135.64636289912 1.2652813736481094 1.0210743040395465 0.7886839066275804 0.895195928854042 0.8544288970439128 1.0199753045950637 0.8376586857720387 0.7913457575856717 0.846474620600277 1.0 15.554818042452668 -4.874430387113449 2.937572585326117 0.8753732420899452 1.293300785730108 0.7158413123408026 0.07449274627395903 0.16796908852195383 2.358115116316134 0.0192160449021311 0.1510306468261494 1.3352716025540766e-05 4.874430387113449 0.4179275436401628 NTEDLTEEWLR ddPTM_PC-9_Lapatinib_30min_R1 2 NTEDLTEEWLR 11 0 G3V4P8;P60983 G3V4P8 GMFB Glia maturation factor beta 0 ; 145.28 0.0005739 5334600.0 13676.0 14408.7 17052.699999999997 12048.099999999999 17072.3 18039.3 13646.8 16094.4 14796.3 12076.599999999999 False True 13480.97773212876 14375.337540417897 15650.692831325576 12934.157465283402 16068.140879433222 17267.801190662172 14353.364529694763 16842.204579495843 13129.784882053546 14164.024218942008 0.9517759588479249 1.0149190172375795 1.1049608917213936 0.9131696801242499 1.134433310128401 1.219131012750556 1.0133676918244425 1.1890832943488066 0.9269812504623269 1.0 13.789943595244747 -3.846033657152014 0.7302201407777068 1.0782097736695568 0.5633014875663219 0.10006431342866173 0.09793274789724074 20.44199930759657 3.00521867349826 0.03742437806268675 11.882167173110908 0.00014254971154951062 3.846033657152014 -0.5149082861032349 NTEES(ph)SSPVRK ddPTM_PC-9_Lapatinib_30min_R1 1 NTEESSSPVRK 11 1 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 NTEES(0.405)S(0.405)S(0.191)PVRK 134.61 9.310799999999999e-05 47325000.0 23160.0 23104.0 21770.0 21465.0 25058.0 22261.0 22446.0 23612.0 23943.0 21115.0 True False 22829.73415297617 23050.50410750552 19980.154634630173 23043.607705140916 23584.13770592349 21308.948922925534 23608.144050878516 24709.09971984393 21246.287209032544 24764.699616031026 0.9218659829089028 0.9307806864164082 0.8067997974704423 0.9305022092908412 0.9523288419237148 0.8604565875344409 0.9532982195187285 0.9977548729825455 0.8579263039103896 1.0 14.595997501426657 -14.522803466066255 0.1276378136893169 1.2923754089501955 0.8759810228839191 0.19696683995401554 0.053037107284706675 236.85526387727393 1.9128328102035272 17.651875343873645 0.4266514481543163 3.0005200554595447e-15 14.522803466066255 -0.41639438606627643 NTEESSS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 1 NTEESSSPVR 10 0 Q5T200-2;Q5T200;Q5T9K0 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 NTEES(0.006)S(0.125)S(0.869)PVR 77.67399999999999 0.021442 10000000.0 23752.0 27094.0 28397.0 40635.0 34784.0 34826.0 31047.0 35151.0 30556.0 29799.0 True False 31304.64192770896 35851.60564795253 28020.437225729802 31267.22855449172 29954.84201554502 32648.324714602233 33810.12285399149 29719.220639623134 32171.127778689657 28755.746080109697 1.0886395310522765 1.2467631877147165 0.9744291505311174 1.0873384563692199 1.0416993505261452 1.1353669845201835 1.1757692796354846 1.0335054620676274 1.118772146932483 1.0 14.811562649101077 -8.410634244296586 0.00948833253235147 8.720013458802362e-07 2.1509277831905638 0.10136913714306517 0.07452609989650905 4025.538963110912 28.23164728263477 3230.5316790412094 3165.025232461755 3.88477397565993e-09 8.410634244296586 2.150926911189218 NTEESSS(ph)PVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NTEESSSPVR 10 0 Q5T200-2;Q5T200;Q5T9K0 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 NTEES(0.007)S(0.044)S(0.949)PVR;NT(0.002)EES(0.009)S(0.033)S(0.957)PVR 91.09299999999999 0.0082915 17441600.0 95912.0 140444.0 118744.0 113598.0 126836.0 104078.0 119261.0 103072.0 99165.0 89966.0 True False 112148.00725165095 154386.35215793923 121575.30729912747 107233.47234968522 101983.39629984458 98619.96646115229 107963.73470513169 100366.4692138112 100615.10052325155 106276.12362953597 1.0552512024486664 1.4526908480037242 1.1439569222803267 1.0090081260724793 0.9596077916366685 0.9279597626737686 1.0158794940760025 0.9443933951117278 0.9467328792869979 1.0 16.6974579867302 -5.66581797022744 3.156877456205269 0.9666715542566692 1.2622511155448117 0.6019652212390183 0.0937991829225304 0.14168566952898284 2.798843104064861 0.02465267119816843 0.04596464756078056 2.158648993634654e-06 5.66581797022744 0.29557956128814256 NTEESSS(ph)PVRK ddPTM_PC-9_AZD4547_30min_R2 1 NTEESSSPVRK 11 1 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 NTEES(0.197)S(0.197)S(0.607)PVRK 73.36 0.036629 4614400.0 23903.0 20660.0 24539.0 28899.0 24412.0 24918.0 19797.0 25430.0 25705.0 34106.0 True False 31503.656786713844 27337.940971680033 24213.596826502242 22236.782035099208 21022.815181792925 23359.87352088836 21558.894648129248 21500.3778232658 27063.713822202426 32911.95932105845 0.9572100062288448 0.8306385136477752 0.7357081536926113 0.675644431198333 0.6387591506392525 0.7097685462299941 0.6550474384651711 0.6532694578748145 0.8223063707084108 1.0 15.006324295365493 -4.94047059453771 1.9294991245105806 0.7130620549469525 0.988948894636995 0.2871382159550242 0.10412270616336412 0.5902650964766153 3.0442588226845717 0.026719027524167095 0.26310025823851824 1.1469101744518521e-05 4.94047059453771 0.27588683969004246 NTEESSS(ph)PVRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NTEESSSPVRK 11 1 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 NTEES(0.189)S(0.189)S(0.622)PVRK;NT(0.001)EES(0.162)S(0.162)S(0.676)PVRK;NT(0.001)EES(0.186)S(0.186)S(0.626)PVRK 103.14 0.0044518 82678000.0 57664.0 68028.0 65629.0 73771.0 93560.0 81277.0 68418.0 76763.0 70476.0 68781.0 True False 67425.37628408537 74781.37025861043 67193.84425936862 69637.8500388091 75227.58962607954 77014.69104001885 61936.95173657543 74748.05258712171 71506.57817250707 81250.45082990377 0.8298461804875283 0.9203809885949281 0.8269965713794944 0.8570764756074348 0.9258728887986977 0.9478678610811354 0.7622967147128725 0.9199709272211338 0.880076078866377 1.0 16.310088197602667 -14.522878737307966 0.35091887437351693 2.4456577578805674 0.8718486961227926 0.3287608356237236 0.05406556228984492 534.2829942713448 4.370776772713724 581.186288882588 0.04081123872260515 3.000000055071191e-15 14.522878737307966 -1.5738090617577747 NTENCDFLFS(ph)PPEVTGR ddPTM_PC-9_AZD4547_30min_R2 4 NTENCDFLFSPPEVTGR 17 0 A0A494BZT8;Q9Y6A5;E7EMT0;C9JA91;Q8IX09;C9JWI7;F8WC55 A0A494BZT8 TACC3;ERIC-1s Transforming acidic coiled-coil-containing protein 3 1 NTENCDFLFS(1)PPEVTGR;NTENCDFLFS(0.934)PPEVT(0.066)GR;NTENCDFLFS(1)PPEVTGR;NTENCDFLFS(1)PPEVTGR 216.16 2.3311e-22 13134100.0 44955.9 48062.5 41185.9 53989.2 46026.7 46673.9 37951.5 55599.6 38801.7 44419.6 True False 59250.94105919042 63597.76321158626 40639.748055610995 41542.824064825 39636.68718367315 43755.37365465092 41329.10997820262 47007.95937170463 40852.678646759465 42864.48332427399 1.3822852036020423 1.4836936848267361 0.9480983999776071 0.9691665650218968 0.9246976543218252 1.0207838812295311 0.9641807569577797 1.0966645513042776 0.9530659296113515 1.0 15.387495133236976 -5.262441649486714 24.998829495670503 0.9859095139345899 1.432989474943983 0.925671922408114 0.05082424900665485 19.062177598901226 475467.95655106514 0.01304673756160941 0.02992941546098483 5.4645996568344416e-06 5.262441649486714 0.4470799610093932 NTENCDFLFS(ph)PPEVTGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NTENCDFLFSPPEVTGR 17 0 A0A494BZT8;Q9Y6A5;E7EMT0;C9JA91;Q8IX09;C9JWI7;F8WC55 A0A494BZT8 TACC3;ERIC-1s Transforming acidic coiled-coil-containing protein 3 1 NTENCDFLFS(1)PPEVTGR;NTENCDFLFS(0.99)PPEVT(0.01)GR;NTENCDFLFS(0.994)PPEVT(0.006)GR 149.42 6.2747e-05 11380900.0 24767.199999999997 24212.1 27161.6 21912.2 25499.600000000002 18345.9 19880.7 17940.6 16505.2 14519.699999999999 True False 28959.797785502233 26615.717275805597 27809.235554941617 20684.530474310905 20503.136430410228 17383.808707888842 17997.456172196413 17469.678259636967 16746.55732522936 17152.00667211803 1.6884203894684067 1.551755300974293 1.6213400616353404 1.2059539661872496 1.195378291435703 1.0135145723880592 1.0492915794775621 1.018520957552759 0.9763614045493721 1.0 14.066089751665196 -5.937442701734201 1.1669945931642605 1.011704790591472 1.6699443998024768 0.9453883208707677 0.06227053574242631 0.09811347160506839 0.2701004075717778 0.022137033225822802 0.04706370570247731 1.1549343498999104e-06 5.937442701734201 0.6582396092110048 NTENCDFLFS(ph)PPEVTGR ddPTM_PC-9_Lapatinib_30min_R1 1 NTENCDFLFSPPEVTGR 17 0 A0A494BZT8;Q9Y6A5;E7EMT0;C9JA91;Q8IX09;C9JWI7;F8WC55 A0A494BZT8 TACC3;ERIC-1s Transforming acidic coiled-coil-containing protein 3 1 NTENCDFLFS(1)PPEVTGR 172.99 7.6151e-06 5844700.0 10906.0 17053.0 20014.0 16639.0 15688.0 16172.0 13823.0 14280.0 14532.0 15955.0 True False 10750.47844008454 17013.51482623319 18368.526176274157 17862.687566076853 14765.262683794712 15480.36125877327 14538.68730354155 14943.500931703 12895.253131255937 18712.800491298833 0.5744986403870094 0.9091912690537269 0.9816022024504159 0.9545705130764757 0.7890461233026203 0.8272605303504091 0.7769380809837533 0.7985710604167185 0.6891140178217596 1.0 14.191737862904667 NTETQPTS(ph)PQLGTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NTETQPTSPQLGTK 14 0 O95696-2 O95696-2 BRD1 Bromodomain-containing protein 1 1 NT(0.001)ET(0.014)QPT(0.242)S(0.743)PQLGTK 97.823 0.011468 0.0 15583.0 25737.0 24133.0 24183.0 30861.0 24820.0 29549.0 24660.0 27146.0 18050.0 True False 18220.894121720714 28291.99927009258 24708.422244912155 22828.104912343824 24814.00858754217 23518.395506887144 26749.904803766036 24012.701129429763 27542.958894813535 21322.322116278618 0.8545454862915656 1.3268723320005062 1.158805411069576 1.0706200191448947 1.163757326815629 1.1029941006721742 1.2545493243132138 1.1261766424163138 1.2917429323415832 1.0 14.380076943500693 NTFGS(ph)TSLCFDSR ddPTM_PC-9_AZD4547_30min_R2 1 NTFGSTSLCFDSR 13 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5;A0A087WZJ0 Q8NEV8-2 EXPH5 Exophilin-5 1 NT(0.001)FGS(0.613)T(0.193)S(0.193)LCFDSR 198.48 6.8071e-07 38468000.0 71050.0 50601.0 78988.0 92999.0 85024.0 81791.0 74537.0 87132.0 62493.0 82434.0 True False 93642.42206819281 66956.78369351316 77940.5675101576 71559.51737022704 73219.88522106996 76676.59584023517 81170.64860269774 73667.75149417206 65796.25239801189 79548.01075095666 1.1771811913859411 0.8417153749216529 0.9797927914774447 0.8995764531970581 0.9204489782943994 0.9639033725216446 1.0203982203504889 0.9260791162308998 0.8271263074572938 1.0 16.279538233228173 -4.747850357103675 24.99927982386534 0.9327287785819894 1.1771817927513413 0.6014315249584803 0.06010628646314155 479.3709598928784 881831.9786248923 0.014733564414202 0.2871963843339344 1.787103242903616e-05 4.747850357103675 0.24445301416935183 NTFGS(ph)TSLCFDSR ddPTM_PC-9_Lapatinib_30min_R1 1 NTFGSTSLCFDSR 13 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5;A0A087WZJ0 Q8NEV8-2 EXPH5 Exophilin-5 1 NTFGS(0.615)T(0.192)S(0.192)LCFDSR 214.58 2.3208e-14 27029000.0 52023.0 51104.0 60460.0 52764.0 52498.0 60944.0 51960.0 43231.0 65400.0 37244.0 True False 51281.14248015024 50985.671827820406 55489.21218234912 56644.440575544126 49410.17085503915 58337.5671874028 54650.234557767435 45239.67008252468 58033.96330746887 43681.57577548946 1.173976477948514 1.167212283958616 1.2703115946995012 1.2967581771014858 1.131144423657997 1.3355188349257558 1.2511049243885723 1.0356693704238915 1.3285684473872117 1.0 15.41473728073576 -10.88148375166226 4.685059298528236 0.9997831298562491 1.219368035665724 0.3510304257736534 0.09017575598188353 0.00019857973997598597 2.7185959612397592e-05 0.08487971194062008 0.0205661362910572 1.3137606460044821e-11 10.88148375166226 0.21958490580947487 NTFGST(ph)SLCFDSR ddPTM_PC-9_AZD4547_30min_R2 2 NTFGSTSLCFDSR 13 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5;A0A087WZJ0 Q8NEV8-2 EXPH5 Exophilin-5 1 NTFGS(0.004)T(0.498)S(0.498)LCFDSR;NTFGS(0.042)T(0.479)S(0.479)LCFDSR 214.58 5.6746000000000005e-14 41179400.0 60887.0 50382.0 70502.0 104293.0 80951.0 75716.0 74921.0 86307.0 80759.0 92991.0 True False 80247.79947172508 66666.99622629149 69567.09741481158 80249.8601607876 69712.3509659724 70981.46655058935 81588.8238587912 72970.2362875582 85027.75586723391 89735.4133942577 0.8942712407101949 0.7429285017430767 0.7752468594440473 0.8942942047662412 0.7768655464892903 0.791008408672819 0.9092154454153569 0.813171004929339 0.9475384650389871 1.0 16.453389825626736 -8.398624140784634 0.8811581529502605 1.003027971414314 0.8119515182556837 0.5339242691027487 0.055664388660967505 0.44661433214533175 0.7668775302379812 0.05168771402230696 0.018519216918840856 3.993703870744904e-09 8.398624140784634 -0.1910764531586303 NTFGST(ph)SLCFDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NTFGSTSLCFDSR 13 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5;A0A087WZJ0 Q8NEV8-2 EXPH5 Exophilin-5 1 NTFGS(0.129)T(0.435)S(0.435)LCFDSR;NT(0.001)FGS(0.065)T(0.565)S(0.369)LCFDSR;NTFGS(0.005)T(0.498)S(0.498)LCFDSR 184.0 0.00013282 46117500.0 141304.0 149034.0 131856.0 159623.0 146567.0 173283.0 165308.0 179360.0 156966.0 131884.0 True False 165223.97631878452 163829.11058860674 134999.94710666462 150679.8408147485 117848.248490013 164195.7344327127 149648.82951372143 174651.99004762893 159261.33079950296 155793.5252068301 1.0605317268444543 1.0515784296626491 0.8665311791837299 0.9671765281304681 0.7564386795507625 1.0539316971917023 0.9605587222899603 1.12104780873122 1.022258984050005 1.0 17.249275750544328 NTFGST(ph)SLCFDSR ddPTM_PC-9_Lapatinib_30min_R1 2 NTFGSTSLCFDSR 13 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5;A0A087WZJ0 Q8NEV8-2 EXPH5 Exophilin-5 1 NTFGS(0.014)T(0.493)S(0.493)LCFDSR;NT(0.001)FGS(0.138)T(0.431)S(0.431)LCFDSR 198.81 1.5433000000000001e-06 11838900.0 48240.0 42668.0 52243.0 47761.0 49020.0 48027.0 43756.0 37266.0 57706.0 37109.0 True False 47552.08875386747 42569.20486751411 47947.78220381189 51273.503266025386 46136.7399770281 45972.99716640516 46021.471580247686 38997.51440622153 51206.54260888072 43523.24120536566 1.0925677278833987 0.9780798416793018 1.1016592715962699 1.178071803616139 1.0600483488656227 1.056286156388957 1.057399915670206 0.896015860174812 1.1765333001570628 1.0 15.409498378619046 -7.127163361599447 2.2474531173398122 1.0231016349796647 1.081719961151413 0.08040401502640793 0.07880857619350225 0.7951087284482442 7.877581111958331 0.03549486169863611 0.02558329680624934 7.46168031537573e-08 7.127163361599447 0.058618326171748336 NTFGSTS(ph)LCFDSR ddPTM_PC-9_AZD4547_30min_R2 1 NTFGSTSLCFDSR 13 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5;A0A087WZJ0 Q8NEV8-2 EXPH5 Exophilin-5 1 NTFGS(0.053)T(0.2)S(0.747)LCFDSR 151.22 0.00013235 5808600.0 21819.0 15604.0 21079.0 35296.0 22761.0 21326.0 18767.0 27343.0 24824.0 28251.0 True False 28756.988136606655 20647.687847148867 20799.47868722608 27159.05251776398 19601.0280334585 19992.48184872242 20437.22664350364 23117.767629632577 26136.145960799575 27261.941088935164 1.0548400806382157 0.7573814270888132 0.7629492932793399 0.9962259264358493 0.7189887165229769 0.7333477019667096 0.7496614630936357 0.8479868529616702 0.9587045132089836 1.0 14.734600667286193 -8.284147546903771 3.0922877855172586 0.9947717862433385 0.8177534178240787 0.2433857675596447 0.10794952199843535 0.34966717206534464 6.360537064062218 0.09901765828312672 0.028019944282399754 5.198193634633546e-09 8.284147546903771 -0.17701836841925978 NTFGSTS(ph)LCFDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NTFGSTSLCFDSR 13 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5;A0A087WZJ0 Q8NEV8-2 EXPH5 Exophilin-5 1 NTFGS(0.065)T(0.216)S(0.718)LCFDSR 146.27 0.0001028 8196200.0 30710.0 27279.0 28322.0 29781.0 39662.0 30513.0 41334.0 42012.0 31652.0 27009.0 True False 35908.59644985194 29987.078839369613 28997.303891783136 28112.467121304697 31890.515816049297 28912.844564933424 37418.54428775476 40909.229515393505 32114.850620299043 31905.51789687364 1.1254666533205078 0.9398712453530801 0.908849183564719 0.8811161508855928 0.9995297966679986 0.9062020136575354 1.1727922552049008 1.282199199762939 1.0065610194481724 1.0 14.961518331879399 -7.264290009228251 24.95982332697685 1.1389047248843076 0.9551123395756995 0.3573587000210273 0.09986229935172279 237.29700490603702 2077730.1971566952 0.039856364225400204 0.028229911953737103 5.4413917117658247e-08 7.264290009228251 -0.18379238530860809 NTFGSTS(ph)LCFDSR ddPTM_PC-9_Lapatinib_30min_R1 1 NTFGSTSLCFDSR 13 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5;A0A087WZJ0 Q8NEV8-2 EXPH5 Exophilin-5 1 NTFGS(0.02)T(0.224)S(0.756)LCFDSR 164.7 0.00032434 28436000.0 39565.0 42546.0 49605.0 43540.0 47924.0 47076.0 43041.0 35004.0 52509.0 34214.0 True False 39000.79584466763 42447.48735101846 45526.668380837385 46742.076845182164 45105.20454220914 45062.6692195159 45269.45237876959 36630.41362838455 46594.883475716866 40127.844312710666 0.9719135556034332 1.0578063207241122 1.1345405954542298 1.1648290020497416 1.124037568295735 1.1229775730873763 1.128130682176473 0.9128427967106549 1.1611608914899458 1.0 15.2923160354706 -10.258274643998348 6.318391029828045 0.9999999991036929 1.0876435733904521 0.09688630775351559 0.07912834366114872 1.0178037748215477e-09 1.8360704570205628e-10 0.07785307223273034 0.018882143394281112 5.517284207491759e-11 10.258274643998348 0.08764357428675928 NTFT(ph)AWSDEESDYEIDDR ddPTM_PC-9_Lapatinib_30min_R1 1 NTFTAWSDEESDYEIDDR 18 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50 Q6PKG0 LARP1 La-related protein 1 1 NTFT(0.704)AWS(0.295)DEESDYEIDDR 144.4 3.3671999999999997e-09 0.0 943.35 998.67 570.09 2006.5 2525.8 3062.8 2072.6 2137.7 950.56 2522.5 True False 929.8976560107973 996.3576409731013 523.2194008110392 2154.064703487781 2377.237409913862 2931.8111837355186 2179.9090866903143 2237.0253460575277 843.4979229594443 2958.510763980027 0.31431275063533115 0.33677675035149124 0.17685228905747238 0.7280908792739897 0.8035250163213233 0.9909753310450727 0.7368264848756964 0.7561322315583199 0.2851089586115627 1.0 11.530655428731713 -5.772584573230391 22.736668474696458 0.7578934805884834 0.28206026655881355 0.5780232297714902 0.1884112858078322 49.66355434750431 101316.25160346198 0.05355996840704248 0.08047527944740272 1.6881670787819213e-06 5.772584573230391 -0.4758332140296698 NTFTAWS(ph)DEESDYEIDDR ddPTM_PC-9_AZD4547_30min_R2 1 NTFTAWSDEESDYEIDDR 18 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50 Q6PKG0 LARP1 La-related protein 1 1 NTFT(0.018)AWS(0.981)DEES(0.001)DYEIDDR 135.81 4.8270999999999996e-08 0.0 1099.6 2470.2 1982.7 736.34 1084.8 2583.5 2485.1 2569.5 1231.1 1167.4 True False 1449.2499268991558 3268.6438426061964 1956.408102526834 566.5881893395945 934.1942450110184 2421.953336592629 2706.269085723392 2172.4428162360005 1296.1734326595365 1126.5296813289058 1.2864729184849835 2.901515953623481 1.7366680478573506 0.5029500764429227 0.8292673158056522 2.149924122492345 2.40230606487967 1.928438151468222 1.1505896863103608 1.0 10.137669610256642 NTFTAWS(ph)DEESDYEIDDR ddPTM_PC-9_Lapatinib_30min_R1 1 NTFTAWSDEESDYEIDDR 18 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50 Q6PKG0 LARP1 La-related protein 1 1 NTFT(0.001)AWS(0.985)DEES(0.013)DYEIDDR 116.13 0.0001236 987230.0 1184.6 2528.4 1208.3 576.99 1959.5 909.77 1908.3 1277.7 1154.2 2118.8 True False 1167.7073867709657 2522.5456451444325 1108.9582381728817 619.423769382215 1844.2460625252238 870.8612578774525 2007.1024366163879 1337.0666064731736 1024.2018417351776 2485.0317568764663 0.4698963639155674 1.0150959391823302 0.4462551575464672 0.2492619129184864 0.7421418488604463 0.3504427078115381 0.8076767755834209 0.5380480964773605 0.4121483916256012 1.0 11.279048573148017 -11.186430513001476 2.600478417376892 1.0578368099864413 0.5659359982592123 0.26433696313222155 0.2204375400827001 36619817.58590863 31081379.06953516 14086567.107848808 0.05582009219094091 6.5098275957208955e-12 11.186430513001476 -0.491900811727229 NTFTAWS(ph)DEESDYEIDDRDVNK ddPTM_PC-9_AZD4547_30min_R2 3 NTFTAWSDEESDYEIDDRDVNK 22 1 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50 Q6PKG0 LARP1 La-related protein 1 1 NT(0.018)FT(0.205)AWS(0.712)DEES(0.053)DY(0.012)EIDDRDVNK;NT(0.011)FT(0.09)AWS(0.628)DEES(0.208)DY(0.063)EIDDRDVNK;NT(0.001)FT(0.052)AWS(0.92)DEES(0.005)DY(0.022)EIDDRDVNK 72.935 0.0005821000000000001 38611800.0 34878.8 31219.8 38794.0 59220.0 49080.0 43825.0 39552.4 46175.0 37994.1 44026.0 True False 45969.53287589153 41310.98981353612 38279.566212450714 45567.74393987942 42266.08918246751 41084.6158220135 43072.4869768484 39039.71474594172 40002.39055950752 42484.66314047145 1.0820265356441146 0.9723741877614825 0.9010208245239703 1.0725692655068033 0.9948552267607432 0.9670458180678323 1.0138361421022304 0.9189131291181634 0.9415725017577158 1.0 15.374654505399922 -7.752924890671126 24.992297690355848 0.9476821087574425 0.9968865137668809 0.1391041134166373 0.052489825659559036 343.94111795584774 1009566.3973820405 0.025115636453273246 0.014200997962039726 1.766343275606573e-08 7.752924890671126 0.049204405009438346 NTFTAWS(ph)DEESDYEIDDRDVNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NTFTAWSDEESDYEIDDRDVNK 22 1 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50 Q6PKG0 LARP1 La-related protein 1 1 NT(0.018)FT(0.11)AWS(0.746)DEES(0.11)DY(0.016)EIDDRDVNK;NT(0.005)FT(0.128)AWS(0.865)DEES(0.002)DYEIDDRDVNK 65.278 0.0014161 17171800.0 22545.0 22979.0 22160.9 23513.0 29175.0 24461.0 26239.0 24705.0 24858.0 17730.9 True False 26361.423215952866 25260.203257079593 22689.29990168126 22195.642840174536 23458.368184489875 23178.22209887053 23753.451966090823 24056.5199271112 25221.50122328429 20945.37181227283 1.2585798644312691 1.2060040510848562 1.0832607845321984 1.0596919949241062 1.1199785993173235 1.1066035163572208 1.134066856343539 1.1485363039970198 1.2041562904367198 1.0 14.354343874017006 -5.084813157302245 3.8652433044474246 1.1123637650873537 1.2501482124682088 0.4923948090448672 0.051770555704708426 0.18896055335527717 5.108668405892834 0.01346355849641768 0.044855855292925434 8.225964722808061e-06 5.084813157302245 0.13778444738085516 NTFTAWS(ph)DEESDYEIDDRDVNK ddPTM_PC-9_Lapatinib_30min_R1 4 NTFTAWSDEESDYEIDDRDVNK 22 1 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50 Q6PKG0 LARP1 La-related protein 1 1 NT(0.012)FT(0.172)AWS(0.803)DEES(0.012)DYEIDDRDVNK;NT(0.001)FT(0.012)AWS(0.983)DEES(0.004)DYEIDDRDVNK;NT(0.001)FT(0.021)AWS(0.962)DEES(0.004)DY(0.012)EIDDRDVNK;NT(0.007)FT(0.013)AWS(0.933)DEES(0.028)DY(0.02)EIDDRDVNK 97.62100000000001 6.3008e-05 60639500.0 80035.0 58043.6 73603.7 70159.0 66057.0 60487.8 57108.1 64682.1 65077.0 63784.5 True False 78893.68622337855 57909.20361038814 67552.28790449833 75318.72690356294 62171.65713305882 57900.877797948684 60064.87798592064 67687.4664996154 57747.34296880966 74809.56583749618 1.0545935581921975 0.7740882193619522 0.9029899739190794 1.006806095722742 0.8310656055418121 0.773976925941836 0.8029037104211454 0.9047969433033252 0.7719245837390682 1.0 16.19093513768302 -6.326332336891967 24.99528254363152 0.8367839561854009 0.920894125498832 0.16075117372573 0.09366227880908062 372.59260908838877 143512.91711506151 0.028103065947557196 0.03186588417213886 4.717019407676838e-07 6.326332336891967 0.08411016931343107 NTGIICTIGPAS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 NTGIICTIGPASR 13 0 P14618;P14618-2;H3BTN5;B4DNK4;H3BQ34;H3BUW1;H3BTJ2;H3BT25;H3BU13 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 1 NTGIICTIGPAS(1)R;NTGIICTIGPAS(1)R 86.777 0.007426899999999999 16762900.0 40305.0 51632.0 56774.0 87399.0 73240.0 76320.0 57403.0 56882.0 58847.0 58881.0 True False 53121.15160392007 68321.03428120929 56021.13966452736 67250.51085108952 63071.89021442378 71547.69833510727 62511.75579565411 48092.19391832502 61957.53228146847 56819.59411198156 0.9349090297834142 1.202420315543972 0.9859475510176897 1.1835795714863862 1.1100376762656916 1.2592081913520743 1.1001795555324505 0.8464015744910752 1.0904254641340965 1.0 15.794100905291566 -7.5563828955786185 24.100193538434436 0.9757059093332162 1.1195700077531123 0.24359695440090956 0.10629022215043608 163.25430445446037 117429.55176381484 0.04744726637380026 0.027393935191171948 2.7772636145521236e-08 7.5563828955786185 0.1438640984198961 NTGIICTIGPAS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 3 NTGIICTIGPASR 13 0 P14618;P14618-2;H3BTN5;B4DNK4;H3BQ34;H3BUW1;H3BTJ2;H3BT25;H3BU13 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 1 NTGIICTIGPAS(1)R;NTGIICTIGPAS(1)R;NTGIICTIGPAS(1)R 101.04 0.0021033000000000002 17606800.0 102148.0 85773.0 83582.0 69157.0 89333.0 77933.0 80960.0 75294.0 70770.0 78776.0 True False 100691.35078835089 85574.39788837754 76710.21059585031 74243.03648098896 84078.60857543554 74599.98726069614 85151.71265967771 78792.43411426083 62799.137358862026 92392.32663757792 1.0898237381046487 0.9262067641618694 0.8302660338531905 0.8035627977225626 0.9100172236731939 0.807426222237321 0.9216318687773439 0.8528027919822324 0.6797007894952207 1.0 16.495485417537033 -4.818794167769738 2.4818443304347486 0.8471682485245855 1.1323634552426065 0.44775317698559847 0.08058519876956442 0.4173837933301779 3.4862167957828025 0.0200817944722586 0.24863822525923251 1.5177695381648765e-05 4.818794167769738 0.285195206718021 NTGIICTIGPASR ddPTM_PC-9_Lapatinib_30min_R1 2 NTGIICTIGPASR 13 0 P14618;P14618-2;H3BTN5;B4DNK4;H3BQ34;H3BUW1;H3BTJ2;H3BT25;H3BU13 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ; 166.62 0.00096017 79878000.0 80191.0 90099.0 68800.0 61122.0 74083.0 66405.0 83785.0 74630.0 66121.0 59588.0 False True 79047.46163477153 89890.3813011659 63143.52957568014 65617.1157770148 69725.58359278196 63565.01294761561 88122.9773368465 78097.58225020974 58673.75669500232 69887.70640398092 1.1310638981030985 1.2862116375884614 0.9034998116933965 0.9388935358347537 0.9976802384919914 0.9095306774010091 1.2609224407431243 1.1174723891891976 0.8395433147547129 1.0 16.092751080216864 -5.257426880869071 24.99975437592932 1.0045402319290524 1.2086377722820114 0.33681213598383075 0.1188940988410468 414.228099196202 2580809.1102960543 0.0318467626364693 0.07805394266756177 5.5280647227755935e-06 5.257426880869071 0.20409754035295902 NTGNGTQSS(ph)MGSPLTRPTPR ddPTM_PC-9_AZD4547_30min_R2 1 NTGNGTQSSMGSPLTRPTPR 20 1 E3W994;J3KR49;O75122;A0A0U1RQI6;H7C4I5;E7ERI8;E7EW49;O75122-3 E3W994;E7ERI8 CLASP2 CLIP-associating protein 2 1 NTGNGTQS(0.039)S(0.845)MGS(0.11)PLT(0.005)RPT(0.001)PR 85.06200000000001 0.0011892 13006000.0 22131.0 18669.0 22677.0 31067.0 21042.0 23790.0 21292.0 24462.0 21823.0 23287.0 True False 29168.197646603498 24703.389157807105 22376.28816311143 23904.98313036529 18120.68151135864 22302.407539205968 23186.946751930493 20681.95998083868 22976.5192274625 22471.729218011154 1.2979952438740274 1.0993096667437265 0.9957528388681709 1.0637803125184233 0.8063768184263659 0.9924651246389408 1.0318274364638609 0.9203546278166271 1.0224633362459155 1.0 14.455823524906652 -4.460967932168677 1.1368189521742806 0.9686292924513599 1.6867531648768304 0.6833249794083167 0.06725900524368336 1.7021024040613253 1.1379311596445552 0.020441914156002095 1.7368669671474692 3.4596492255592054e-05 4.460967932168677 0.7181238724254705 NTGNGTQSS(ph)MGSPLTRPTPR ddPTM_PC-9_Lapatinib_30min_R1 2 NTGNGTQSSMGSPLTRPTPR 20 1 E3W994;J3KR49;O75122;A0A0U1RQI6;H7C4I5;E7ERI8;E7EW49;O75122-3 E3W994;E7ERI8 CLASP2 CLIP-associating protein 2 1 NTGNGT(0.001)QS(0.169)S(0.548)MGS(0.055)PLT(0.05)RPT(0.177)PR;NTGNGT(0.002)QS(0.181)S(0.793)MGS(0.024)PLTRPTPR 136.43 3.6461e-09 5957100.0 25360.8 18925.6 18068.6 18549.2 21440.7 21381.4 20292.9 21923.0 23446.9 19212.0 True False 24999.15034139886 18881.778935985403 16583.069454812998 19913.370046317246 20179.60018003805 20466.967364477812 21343.567068077726 22941.622613846277 20806.063215197133 22532.768601619136 1.1094575541685765 0.8379697705957276 0.7359534794859336 0.8837515885591766 0.8955668314362402 0.9083201326181958 0.9472234613257441 1.0181448635742774 0.923369142205724 1.0 14.459736967975406 -7.215541368794964 1.885178427702204 0.9790033990044839 0.8801186016901069 0.15010870518723296 0.08984172420246364 0.6396711245801892 4.4467600434037475 0.04714857341305557 0.03073029261518381 6.087775537896779e-08 7.215541368794964 -0.09888479731437694 NTGVSPASRPSPGTPT(ph)SPSNLTSGLK ddPTM_PC-9_AZD4547_30min_R2 2 NTGVSPASRPSPGTPTSPSNLTSGLK 26 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 NTGVSPASRPSPGT(0.001)PT(0.789)S(0.167)PS(0.039)NLT(0.003)S(0.001)GLK;NTGVSPASRPS(0.006)PGT(0.056)PT(0.452)S(0.452)PS(0.03)NLT(0.002)S(0.001)GLK 92.51799999999999 1.5017999999999999e-07 128289000.0 82203.0 76151.0 80767.0 136163.0 109493.0 105937.0 84503.0 106444.0 84924.0 96146.0 True False 108341.84407138162 100765.32153603128 79695.97680777969 104772.72404737932 94291.78693675445 99312.74264316385 92023.60329599776 89995.52563978382 89412.90926421779 92779.95780456488 1.167728964692966 1.086067766362721 0.8589783687513011 1.1292603114573132 1.0162947814157681 1.0704115952753488 0.9918478675086236 0.9699888614883153 0.9637093115795593 1.0 16.501525569613477 -5.0061087916111315 20.672462939884394 1.0041440912205606 1.1473147589887627 0.3897986245645543 0.06682277938802388 28.286599187157424 95758.97622639433 0.016451945417684622 0.05524846322326611 9.860324516472095e-06 5.0061087916111315 0.1431706677682021 NTGVSPASRPSPGTPT(ph)SPSNLTSGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NTGVSPASRPSPGTPTSPSNLTSGLK 26 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 NTGVSPAS(0.001)RPS(0.003)PGT(0.001)PT(0.546)S(0.407)PS(0.033)NLT(0.005)S(0.002)GLK 64.547 0.00038021 46723000.0 57509.0 56487.0 47238.0 78245.0 84562.0 80517.0 80723.0 74872.0 64640.0 61101.0 True False 67244.13784547486 62094.65605042228 48364.33307111262 73861.18632371257 67992.68313339625 76294.54677792237 73076.33305608998 72906.68933344152 65585.23771313451 72178.12762475012 0.9316414827920338 0.8602974071764341 0.6700691007469183 1.0233181263403308 0.9420122878067195 1.05703139286978 1.0124442883308025 1.0100939402651057 0.908658064034417 1.0 16.13927409826916 -5.794549757818896 24.999999381015115 0.9950940758353859 0.8246318986399334 0.545695078712156 0.07216966082650611 136.61011343701603 103146.9441784082 0.020384089106496507 0.030236585316184512 1.6049083706237366e-06 5.794549757818896 -0.17046217719545254 NTGVSPASRPSPGTPT(ph)SPSNLTSGLK ddPTM_PC-9_Lapatinib_30min_R1 1 NTGVSPASRPSPGTPTSPSNLTSGLK 26 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 NTGVSPASRPSPGTPT(0.914)S(0.082)PS(0.004)NLTSGLK 93.712 1.9335e-08 42759000.0 60058.0 46336.0 64494.0 56932.0 61750.0 57013.0 59436.0 57492.0 58035.0 61969.0 True False 59201.56190671169 46228.711838875366 59191.55227403942 61118.969199584535 58117.986405171025 54574.686893794285 62513.30525741847 60163.288204864744 51498.487164357124 72680.25908149792 0.8145480307152968 0.6360559582903815 0.8144103092377075 0.8409294349246957 0.7996392299592946 0.7508873466259735 0.860113957317089 0.8277803211653714 0.7085622398044946 1.0 16.149275941869497 -12.04813841414987 2.2690750117500826 4.345086029476795 0.7849587362011496 0.5021798662782962 0.06460842041088188 3480714.2168046795 291948.5145777727 60300845.54734787 0.01724546813126344 8.95079448993577e-13 12.04813841414987 -3.560127293275645 NTGVSPASRPSPGTPTS(ph)PSNLTSGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NTGVSPASRPSPGTPTSPSNLTSGLK 26 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 NTGVSPAS(0.002)RPS(0.005)PGT(0.008)PT(0.164)S(0.55)PS(0.219)NLT(0.037)S(0.016)GLK 53.589 0.0037000999999999996 41684000.0 10361.0 8218.2 10496.0 10611.0 13973.0 10041.0 11980.0 8714.7 12960.0 9910.2 True False 12114.912660922053 9034.048583808317 10746.264446301664 10016.500071326152 11235.090956019782 9514.432283829736 10845.16767231098 8485.948358987904 13149.51548208884 11706.840810899967 1.0348575552203751 0.7716897094386834 0.9179474308983572 0.8556108546380867 0.959703060586512 0.8127241531268683 0.9263957584708333 0.7248709106120957 1.1232334747257888 1.0 13.515064184563165 -8.279447047976044 24.95952083490758 1.0616167573376902 0.8751823028633785 0.4025642393996147 0.09070456569285106 844.5052551772592 1170514.5943791268 0.07859899535814656 0.020466745141864234 5.2547608068525234e-09 8.279447047976044 -0.18643445447431173 NTHEAEVLLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 NTHEAEVLLSPK 12 0 A0A0U1RRJ3;A0A0U1RQP0;A0A0U1RR07;Q9HCH5-11;Q9HCH5-7;Q9HCH5-8 A0A0U1RRJ3 SYTL2 Synaptotagmin-like protein 2 1 NTHEAEVLLS(1)PK;NTHEAEVLLS(1)PK 99.044 0.0019659000000000005 8289700.0 103419.0 103756.0 80886.0 98800.0 103087.0 95589.0 109633.0 95007.0 107814.0 100466.0 True False 136304.0907511672 137293.09794083418 79813.39879002639 76023.18644478363 88775.14946114548 89611.80471900637 119390.12461273685 80325.85119366932 113512.82793335669 96948.71591947062 1.4059401350337295 1.416141478912162 0.8232538000433395 0.784158776356888 0.9156918543911977 0.9243217289586529 1.2314771111760463 0.8285396091309875 1.1708543724049412 1.0 16.56493416958982 -5.251561025224604 24.87783768320348 0.9542528872555159 1.4110408928777263 0.6312334172123524 0.13791075113826098 399.5871775401925 1006322.8198972942 0.03574609527108567 0.09208756316600167 5.60323677517839e-06 5.251561025224604 0.45678800562221034 NTLDSEVPAAYQT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 NTLDSEVPAAYQTPK 15 0 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 NTLDSEVPAAYQT(1)PK;NTLDSEVPAAYQT(1)PK 185.96 9.7479e-07 18459600.0 87776.0 88031.0 94370.0 97751.0 101536.0 115598.0 110942.0 119346.0 114169.0 106774.0 True False 115686.94214578037 116485.29920996938 93118.59213973735 75216.01718789514 87439.47903893684 108369.63878592415 120815.62307686788 100903.81799824952 120203.74025936713 103035.87475947599 1.1227831317571348 1.1305314724787783 0.9037492267339966 0.7299983366325298 0.8486314038004051 1.0517660867042586 1.1725588137034448 0.979307626919231 1.1666202722106966 1.0 16.65278721307201 -6.937266185717692 8.856680272512643 1.0827547316564687 0.9431924995321237 0.20722248441169633 0.12488075886850898 0.5264419071538912 68.40687494800956 0.04914902462454067 0.043325648171406536 1.1554038604613627e-07 6.937266185717692 -0.13956223212434504 NTLDSEVPAAYQT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NTLDSEVPAAYQTPK 15 0 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 NTLDSEVPAAYQT(1)PK;NTLDSEVPAAYQT(1)PK 174.68 5.0588000000000004e-05 14484000.0 90258.0 105284.0 84864.0 99660.0 93658.0 75100.0 91630.0 88486.0 70098.0 69525.0 True False 105536.89672324134 115735.89972228392 86887.47960851213 94076.3733020794 75306.38722957835 71161.6237940058 82950.14305624833 86163.33625866678 71123.05063761304 82129.33214040284 1.2850085830823814 1.409190805599509 1.0579348126193828 1.1454661915581232 0.916924383371821 0.8664580843340188 1.009994126269556 1.0491177026907716 0.8659884207511368 1.0 16.32560994596021 -5.538103389536484 1.359687674340036 0.9581185461197185 1.3656730492936813 0.7397821767537305 0.08561080536120938 0.24480761806243145 0.835451417363688 0.027316012628193834 0.09325524892287725 2.896653918895097e-06 5.538103389536484 0.4075545031739628 NTLDSEVPAAYQT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 NTLDSEVPAAYQTPK 15 0 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 NTLDSEVPAAYQT(1)PK;NTLDSEVPAAYQT(1)PK 191.41 2.3088000000000001e-07 17855100.0 75415.0 89687.0 77953.0 92545.0 89225.0 79149.0 80623.0 85008.0 85381.0 74428.0 True False 74339.56827058276 89479.33526185293 71544.00524728188 99351.06802107004 83976.96092309931 75763.98177533054 84797.2644486313 88957.78201696157 75764.49267821095 87292.78063092382 0.8516118713744774 1.0250485162132013 0.8195867370724713 1.1381361356917816 0.9620149606432645 0.8679295266771562 0.9714121126139441 1.019073758150487 0.8679353794278272 1.0 16.413574723224983 -4.738377541940989 24.26532881884864 0.9622363868328192 0.851611211159993 0.1263425182574126 0.08818293381081867 2944.212698446311 3097625.058377725 0.02102537648580673 1.113779481378472 1.8265116981597988e-05 4.738377541940989 -0.11062517567282615 NTLET(ph)SSLNFK ddPTM_PC-9_Lapatinib_30min_R1 1 NTLETSSLNFK 11 0 Q14151;K7EQU4;K7ERX3 Q14151 SAFB2 Scaffold attachment factor B2 1 NTLET(0.355)S(0.322)S(0.322)LNFK 124.48 0.0012448000000000001 4147800.0 20215.0 37190.0 37355.0 36994.0 38704.0 35109.0 34439.0 29829.0 33106.0 29549.0 True False 19926.73039302303 37103.88883994678 34283.816094469934 39714.66216836632 36427.50681499171 33607.46991307638 36222.08290867883 31214.964236118252 29377.253658364916 34656.50527843243 0.5749780663956302 1.070618302158626 0.9892461983408803 1.1459511525843808 1.051101561520152 0.969730491954453 1.0451741344855303 0.9006956698413578 0.8476692448458467 1.0 15.080838561696932 -4.756103127408822 24.999365275114194 1.0050768690740497 0.5749773916604171 0.7162335676394453 0.0806633109343323 96.91584455689171 453984.07614665123 0.0214393799553746 0.1789023189055526 1.753464075463492e-05 4.756103127408822 -0.43009947741363264 NTLETS(ph)SLNFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NTLETSSLNFK 11 0 Q14151;K7EQU4;K7ERX3 Q14151 SAFB2 Scaffold attachment factor B2 1 NTLET(0.104)S(0.845)S(0.051)LNFK 101.39 0.0037542 3815100.0 28266.0 35290.0 30546.0 29278.0 38038.0 24455.0 29258.0 34086.0 23273.0 20820.0 True False 33050.87552105225 38793.35797651502 31274.332486350082 27637.648580556714 30584.72695806775 23172.53674943292 26486.47043042361 33191.2786171023 23613.32359680968 24594.501188970695 1.3438319105196483 1.5773183476439745 1.2715985677471244 1.123732836385017 1.2435595551652556 0.9421836438717671 1.076926514057596 1.3495406295122099 0.960105814522434 1.0 14.586048175025578 -5.542807431511633 3.1548918131753516 1.1122762183370039 1.4604127864511551 0.5508912321790544 0.12998061476383055 0.17977343028832565 3.670283806097304 0.0353922125301962 0.07330989781364271 2.8654482432886742e-06 5.542807431511633 0.3481365681141513 NTLQLHR ddPTM_PC-9_AZD4547_30min_R2 3 NTLQLHR 7 0 P61313;E7ERA2 P61313 RPL15 60S ribosomal protein L15;Ribosomal protein L15 0 ;; 125.81 0.003843 16563000.0 170965.0 137042.0 187966.0 284672.0 236499.0 213520.0 195511.0 240946.0 180697.0 217521.0 False True 225328.31370708862 181338.14649762693 185473.44802519726 219045.2685385572 203665.19611989355 200168.5606461229 212911.10024500702 203713.33208826618 190248.27451976325 209905.65599823973 1.0734742360109544 0.8639030979667724 0.8836038607113694 1.0435415258195526 0.9702701680492186 0.953612039152492 1.0143180717664535 0.9704994899707444 0.9063513492049908 1.0 17.67938151562941 -5.748829897932078 24.998106712761686 0.9785199138040143 0.9326847003174552 0.0734942493259344 0.06236452992850455 556.9515610835264 1104138.2091247845 0.01669494786498547 0.02866652287092072 1.7830770164697191e-06 5.748829897932078 -0.04583521348655906 NTLQLHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NTLQLHR 7 0 P61313;E7ERA2 P61313 RPL15 60S ribosomal protein L15;Ribosomal protein L15 0 ;; 113.89 0.0074706 14386400.0 134550.0 136318.0 136809.0 172392.0 183378.0 155382.0 167800.0 149310.0 149342.0 127684.0 False True 157326.65751636517 149850.75014572355 140071.04541102154 162733.4351424051 147446.39728998745 147233.49438562212 151904.76923320367 145390.770707022 151525.84422269385 150832.09845401178 1.043058202656602 0.9934937701036664 0.9286554178236057 1.0789045356418083 0.9775531786753161 0.9761416561509495 1.0071116876990143 0.9639246035640827 1.004599457116839 1.0 17.2025839544536 NTLQLHR ddPTM_PC-9_Lapatinib_30min_R1 4 NTLQLHR 7 0 P61313;E7ERA2 P61313 RPL15 60S ribosomal protein L15;Ribosomal protein L15 0 ;;; 113.41 0.0075758 25295200.0 279530.0 259638.0 264299.0 260524.0 289988.0 262784.0 254179.0 234478.0 259921.0 220929.0 False True 275543.85094047635 259036.82416311084 242569.35644364328 279683.8040425877 272931.4759783436 251545.34089942355 267339.1449126015 245372.70388402286 230645.9598905293 259116.28328061133 1.063398438152475 0.999693345719171 0.936140922417259 1.0793756397767664 1.053316574793453 0.9707816803894613 1.0317342527759445 0.9469598003545583 0.8901253019315273 1.0 17.983240154061498 -7.81184125964606 6.403412973134819 0.9375391456001523 1.0170073900701888 0.32875781874272136 0.047706534196447534 0.22980869191884398 20.915030606292465 0.026304869365455927 0.012643208637313727 1.542264067771423e-08 7.81184125964606 0.07946824447003653 NTLQPEEALSTSDPRVS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 NTLQPEEALSTSDPRVSPR 19 1 Q9BXL7 Q9BXL7 CARD11 Caspase recruitment domain-containing protein 11 1 NTLQPEEALST(0.009)S(0.009)DPRVS(0.982)PR;NTLQPEEALSTSDPRVS(1)PR;NTLQPEEALSTSDPRVS(1)PR;NTLQPEEALSTSDPRVS(1)PR 152.57 1.8824e-05 42473800.0 80285.0 84318.0 131808.0 216656.0 206545.0 157538.0 165222.0 214265.0 142950.0 187652.0 True False 105813.9599682599 111572.14457164182 130060.13979818283 166709.30650183247 177869.79197621733 147687.12395592412 179926.43792257496 181155.26756987997 150506.04516179094 181082.36059682342 0.584341620130813 0.6161403253409932 0.718237488011101 0.9206269785327557 0.9822590747656597 0.8155798470329576 0.9936165915308444 1.0004026177525864 0.831146913844855 1.0 17.46628649328747 -5.611172081333802 2.3782350293755425 0.9371674225192281 0.5994935884433052 0.827256648360796 0.0633403187622367 0.11207498209862328 1.2734437366821132 0.01822064098971025 0.03897997266714992 2.4480930370546797e-06 5.611172081333802 -0.3376738340759229 NTLQPEEALSTSDPRVS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NTLQPEEALSTSDPRVSPR 19 1 Q9BXL7 Q9BXL7 CARD11 Caspase recruitment domain-containing protein 11 1 NTLQPEEALSTSDPRVS(0.999)PR;NTLQPEEALS(0.003)T(0.013)S(0.004)DPRVS(0.98)PR;NTLQPEEALSTSDPRVS(1)PR;NTLQPEEALSTS(0.001)DPRVS(0.999)PR 119.18 2.4365e-05 37034900.0 58401.0 58878.0 96850.0 130999.0 177848.0 159278.0 157469.0 171376.0 140805.0 125076.0 True False 68287.13582767178 64723.0187288538 99159.2713056706 123659.55073448816 142999.96109255048 150925.181287106 142552.39634316665 166877.5615878811 142864.00674811073 147751.28869892895 0.46217624515492156 0.43805383559624395 0.6711228861612589 0.8369439740486309 0.9678423948229636 1.0214813191554928 0.9648132182024075 1.1294491104434663 0.9669222380809349 1.0 17.17281118819966 -5.688370786220611 1.1979032261371978 1.0243705511419208 0.40754015248998704 0.957071352885195 0.04737605070415401 0.09142121570473138 0.25067929462779176 0.01588687460865281 0.047083562805256295 2.049411711957691e-06 5.688370786220611 -0.6168303986519337 down NTLQPEEALSTSDPRVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 NTLQPEEALSTSDPRVSPR 19 1 Q9BXL7 Q9BXL7 CARD11 Caspase recruitment domain-containing protein 11 1 NTLQPEEALSTSDPRVS(1)PR;NTLQPEEALSTSDPRVS(1)PR;NTLQPEEALS(0.001)T(0.001)SDPRVS(0.998)PR;NTLQPEEALSTSDPRVS(1)PR 214.95 5.089e-28 34720500.0 154462.9 113692.5 146470.0 144016.0 122212.0 118193.0 106106.8 76037.0 138151.0 82160.6 True False 152260.23072097325 113429.2520014964 134427.80199055056 154607.41706329217 115023.73043803668 113138.16091134005 111600.49091944033 79569.9566067158 122590.97958547606 96361.9502378819 1.5800866456635554 1.1771166079711095 1.3950299019343029 1.604444665987185 1.193663371840086 1.174095798518439 1.1581385665601425 0.8257404132054935 1.272192803101685 1.0 16.5561759716527 -6.669778297334251 1.947564331680355 1.0614862695777285 1.4150377207362055 0.5171217633511144 0.15844027764923124 0.27806427702124503 2.1665137924249076 0.06107397204321363 0.05974008969897744 2.139053774795833e-07 6.669778297334251 0.35355145115847697 NTMEMY(ph)KR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NTMEMYKR 8 1 Q9UI47;Q9UI47-2 Q9UI47 CTNNA3 Catenin alpha-3 1 NT(0.002)MEMY(0.998)KR 44.117 0.043512 3992200.0 12667.0 8488.7 14595.0 19257.0 21058.0 15619.0 13889.0 20967.0 13993.0 11860.0 True False 14811.272915345973 9331.402036136104 14943.00015184573 18178.092722036366 16931.83606611783 14799.912144321937 12573.333372347846 20416.638466372828 14197.62115284483 14010.124116291652 1.0571835618588636 0.6660470641573473 1.0665858509040105 1.297496908032242 1.2085429026591328 1.0563726646155747 0.8974462515808096 1.4572774871160041 1.0133829675595198 1.0 13.774182116272163 -5.505051347048574 23.20365734728453 1.145203068652266 0.8627904332848975 0.2687215768375486 0.17573479557750474 334.48721945806875 435356.7951881102 0.04482441667054919 0.09008221431108769 3.1257097896431117e-06 5.505051347048574 -0.2824126353673686 NTNAAEES(ph)LPEIQK ddPTM_PC-9_Lapatinib_30min_R1 1 NTNAAEESLPEIQK 14 0 Q9NTJ3;E9PD53 Q9NTJ3 SMC4 Structural maintenance of chromosomes protein 4;Structural maintenance of chromosomes protein 1 NT(0.005)NAAEES(0.995)LPEIQK 100.23 0.0020097 3733300.0 9958.2 15687.0 10346.0 11017.0 11128.0 11699.0 8582.0 14962.0 10321.0 8622.5 True False 9816.194241889783 15650.677715306407 9495.391816714917 11827.226931634641 10473.472918489766 11198.661041701002 9026.333967951497 15657.189141466406 9158.540295051784 10112.887636240943 0.9706618519830165 1.5475973112981125 0.9389397131919924 1.1695202554461421 1.0356560158897263 1.1073653188401935 0.8925575258647561 1.5482411853718898 0.9056305799572891 1.0 13.303907383086209 -5.300731595277052 24.996773200954678 1.090966892589683 1.2591309518365372 0.09640643062705279 0.22138859133077607 1125.6004474845445 716078.4745016091 0.054243614830713174 0.11291990644041011 5.0034366419232994e-06 5.300731595277052 0.1681640592468543 NTNPNFVR ddPTM_PC-9_Lapatinib_30min_R1 2 NTNPNFVR 8 0 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580 P35579 MYH9;MYH10 Myosin-9;Myosin-10 0 ; 105.14 0.017725 9253400.0 25203.9 21551.4 22674.3 21183.1 24008.4 18141.4 25017.3 19128.6 18298.9 20296.4 False True 24844.4877641708 21501.49905741407 20810.106579329113 22740.975838750073 22596.273114330495 17365.5346116689 26312.57338341099 20017.384588387526 16237.885186040407 23804.605696746963 1.04368407024553 0.9032495363009677 0.8742050527714867 0.9553183164826695 0.9492395464218257 0.7295031403961462 1.1053564053365839 0.8409038504310541 0.6821320795185197 1.0 14.538953111612821 -4.762738975347338 4.914953124013403 0.8922588500296813 1.0536866728808585 0.12922213651129655 0.11740932502578694 0.3798552366949453 23.439842005965293 0.02861189680355771 0.21297621259058205 1.726875486664819e-05 4.762738975347338 0.16142782285117718 NTPS(ph)PDVTLGTNPGTEDIQFPIQK ddPTM_PC-9_Lapatinib_30min_R1 1 NTPSPDVTLGTNPGTEDIQFPIQK 24 0 M0R3F6;M0R2Z9;Q8IX01-4;Q8IX01-3;Q8IX01 M0R3F6 SUGP2 SURP and G-patch domain-containing protein 2 1 NT(0.118)PS(0.488)PDVT(0.302)LGT(0.09)NPGT(0.001)EDIQFPIQK 77.27600000000001 0.00012508 2491800.0 32697.0 29204.0 29260.0 23904.0 30967.0 29807.0 28599.0 25466.0 31220.0 26193.0 True False 32230.734784104567 29136.379932288408 26854.355746866277 25661.979901406405 29145.581943464484 28532.224093510697 30079.71628401827 26649.243328203687 27703.674838825384 30720.425150021343 1.049163044674926 0.9484367416792786 0.8741531282762087 0.835339347554198 0.9487362821684203 0.9287704826406308 0.9791438802401266 0.8674763841341295 0.9017998515169031 1.0 14.906910561675678 -4.81427960117448 3.403560366949273 0.9129433080362115 1.061617099688413 0.40038490764729784 0.04828504038408314 0.27614549983534065 5.250033219502542 0.012385632094964794 0.10232885819735114 1.5336293059210058e-05 4.81427960117448 0.1486737916522014 NTPS(ph)QHSHSIQHS(ph)PER ddPTM_PC-9_AZD4547_30min_R2 2 NTPSQHSHSIQHSPER 16 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 NT(0.278)PS(0.632)QHS(0.09)HS(0.063)IQHS(0.937)PER;NT(0.352)PS(0.578)QHS(0.074)HS(0.025)IQHS(0.972)PER 54.582 0.031304000000000005 6328000.0 22541.2 24737.6 41291.0 56030.0 49953.0 41975.0 33734.0 44684.0 34943.0 39271.0 True False 29708.832713913485 32733.545429866015 40743.4543609399 43113.14915487071 43017.88820154443 39350.29661446703 36736.26064858275 37779.114536170244 36790.01564245163 37896.13424316211 0.7839541765206323 0.8637700410239701 1.075134843557072 1.137666150278902 1.1351524122623795 1.0383723142306343 0.9693933532339477 0.9969120938235809 0.9708118354866219 1.0 15.209763067189405 -5.130229599546968 3.7980787552577353 1.0443520627343017 0.7991616915406123 0.694214195260598 0.05833479001609345 0.1425529154199593 3.5349872075913256 0.01758501356796071 0.056089177693101795 7.40918434544522e-06 5.130229599546968 -0.24519037119368936 NTPSPFIETFTEDDEASR ddPTM_PC-9_Lapatinib_30min_R1 1 NTPSPFIETFTEDDEASR 18 0 A0A0C4DGB2;E1CEI4;P48506;B4E2I4;A0A2R8YEL6 A0A0C4DGB2 GCLC Glutamate--cysteine ligase catalytic subunit 0 102.15 0.0068958 0.0 8604.6 11283.0 15435.0 13143.0 12384.0 9694.8 10760.0 12777.0 12401.0 10641.0 False True 8481.896826109616 11256.874906725447 14165.993880823002 14109.580063762736 11655.597467880774 9280.176003682605 11317.100150915656 13370.66606473173 11004.268791680766 12480.282671758754 0.6796237752934104 0.9019727519632452 1.1350699542149627 1.13054971869274 0.9339209515066406 0.7435870042176551 0.9067983833831562 1.0713432072326212 0.8817323358053408 1.0 13.607362990394337 -4.812542632163859 3.905424528939473 0.9736544642937621 0.6612321212379203 0.37824680473129013 0.11359604222758925 0.261232859395761 7.053566243370853 0.03151492577248267 0.21668145048199258 1.5397753678464102e-05 4.812542632163859 -0.3124223430558418 NTPSQHS(ph)HSIQHSPER ddPTM_PC-9_AZD4547_30min_R2 1 NTPSQHSHSIQHSPER 16 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 NT(0.117)PS(0.077)QHS(0.742)HS(0.012)IQHS(0.052)PER 76.068 0.006678399999999999 4063400.0 0.0 0.0 725.07 7063.4 2241.9 1984.4 631.03 2367.4 0.0 2278.0 True False 0.0 0.0 715.4550980476786 5435.04225844215 1930.650883010879 1860.3151543001404 687.1904475329089 2001.5727274400108 0.0 2198.2479133692354 0.0 0.0 0.32546606490398383 2.472442814746908 0.87826803849971 0.8462717707980678 0.3126082564908059 0.91053093478079 0.0 1.0 11.102138383969876 -5.5357611589577225 24.999821320978576 0.923305841254767 0.04068263035036906 0.28336794410968746 0.6035386131757546 286.04109716059423 555094.0850929077 0.17057015222001834 0.2956538618632778 2.9123183125030486e-06 5.5357611589577225 -0.882623210904398 NTPSQHSHS(ph)IQHSPER ddPTM_PC-9_AZD4547_30min_R2 1 NTPSQHSHSIQHSPER 16 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 NTPSQHS(0.002)HS(0.665)IQHS(0.332)PER 62.203 0.033125999999999996 2521100.0 0.0 0.0 2787.0 3262.2 3354.0 712.52 575.11 1919.5 700.21 961.87 True False 0.0 0.0 2750.04255900655 2510.150190487582 2888.354994254199 667.966011762717 626.2936758643034 1622.8853807219305 737.2216710929533 928.1952240704426 0.0 0.0 2.962784646689632 2.704334309629115 3.1117968713389934 0.7196395698239703 0.6747434802754089 1.7484310828545768 0.7942528166219094 1.0 9.85828446406842 NTPSQHSHSIQHS(ph)PER ddPTM_PC-9_AZD4547_30min_R2 5 NTPSQHSHSIQHSPER 16 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 NTPSQHSHSIQHS(1)PER;NTPSQHSHS(0.001)IQHS(0.999)PER;NTPSQHSHSIQHS(0.999)PER;NT(0.002)PS(0.028)QHS(0.039)HS(0.006)IQHS(0.925)PER;NTPSQHSHSIQHS(1)PER 120.9 4.769e-05 93037300.0 11147.07 4351.89 58036.799999999996 288240.5 113081.2 84375.09999999999 33395.94 120903.6 47218.0 101862.5 True False 14691.606386540354 5758.553336652696 57267.19411142854 221791.1059963325 97381.82730359494 79099.11165873286 36368.11396349173 102220.72670833631 49713.84708254248 98296.32487953197 0.14946241789350515 0.058583607715854566 0.5825975099436618 2.2563519670562537 0.9906965232214144 0.8047006005125172 0.3699844730518972 1.0399241968976352 0.5057548910752236 1.0 16.584849857384988 -5.522502560807282 24.99999239368676 0.9979420079716451 0.1581646912524629 0.3590759768564553 0.47637464759527537 14.677950135955465 975447.4052608358 0.1372660391563086 0.24120942723736288 3.0025997160498852e-06 5.522502560807282 -0.8397773167191822 NTPSQHSHSIQHS(ph)PER ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 NTPSQHSHSIQHSPER 16 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 NTPSQHSHS(0.001)IQHS(0.999)PER;NTPSQHSHS(0.051)IQHS(0.949)PER;NTPSQHSHS(0.002)IQHS(0.998)PER;NTPSQHSHSIQHS(1)PER;NTPSQHSHS(0.002)IQHS(0.998)PER;NTPSQHSHS(0.001)IQHS(0.999)PER 142.27 1.4695e-05 53083080.0 6558.350000000001 8395.32 33867.1 50134.2 48901.4 55102.49999999999 27844.6 32470.699999999997 38356.100000000006 27954.500000000004 True False 7668.549121683055 9228.751886863027 34674.62010569198 47325.34331126944 39319.521711637135 52212.82789759264 25206.957910553443 31618.378530550483 38916.98539988794 33022.42956229977 0.23222243860693687 0.27946919742692344 1.0500323739134703 1.4331272392295045 1.1906913644090704 1.5811322361696152 0.7633283875433291 0.9574818978991108 1.1785015795542109 1.0 15.011158647242688 -5.281095603422155 4.266090954046946 1.1634082482722707 0.2367078269457616 0.7263926037299795 0.21890263941471355 0.10119672722926955 4.547129131722471 0.06078012275029595 0.14936193089269298 5.234851864817066e-06 5.281095603422155 -0.9267004213265091 down NTPSQHSHSIQHS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 8 NTPSQHSHSIQHSPER 16 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 NTPSQHS(0.002)HS(0.005)IQHS(0.993)PER;NTPSQHSHS(0.001)IQHS(0.999)PER;NTPSQHSHS(0.001)IQHS(0.999)PER;NTPSQHS(0.001)HS(0.032)IQHS(0.967)PER;NTPSQHS(0.001)HS(0.034)IQHS(0.965)PER;NTPSQHSHS(0.006)IQHS(0.994)PER;NTPSQHSHS(0.032)IQHS(0.967)PER;NTPSQHSHS(0.011)IQHS(0.989)PER 92.492 0.0025988000000000005 64628120.0 33388.15 13571.769999999999 84159.2 24274.899999999998 50658.600000000006 87442.7 33474.399999999994 30208.609999999997 91075.7 29759.66 True False 32912.02885836318 13540.345400412056 77239.95543990664 26060.15712469253 47678.96074663964 83702.97955988953 35207.54064050288 31612.21230255269 80817.79559636164 34903.57757874565 0.9429414157935714 0.38793574583762375 2.2129523905005515 0.746632836301621 1.3660193038685378 2.3981203465761634 1.0087086505981073 0.9057012058787572 2.315458792555844 1.0 15.091087298236213 -5.23890932619794 24.94827784876019 1.474498736718066 0.6654385173056475 0.23502562559669982 0.5972283794766604 1136.8152071540737 1258828.9220954853 0.14723597074994982 0.38890606273850853 5.768868956568809e-06 5.23890932619794 -0.8090602194124185 NTS(ph)ASDEDER ddPTM_PC-9_AZD4547_30min_R2 2 NTSASDEDER 10 0 Q32MZ4-2;Q32MZ4;C9JTC6;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 NT(0.01)S(0.69)AS(0.3)DEDER;NT(0.004)S(0.996)AS(0.001)DEDER 105.0 0.0025233 17930100.0 12290.7 8709.5 12539.199999999999 15720.4 13277.099999999999 14405.2 12654.599999999999 13845.6 11997.3 15602.800000000001 True False 16198.88693755863 11524.675551444692 12372.92201503226 12096.304657758867 11433.803844428272 13504.440566783098 13780.834884791451 11706.080660236299 12631.452785026617 15056.550721122712 1.0758697152883325 0.7654260105720508 0.8217633802192416 0.8033914859921443 0.7593906503690704 0.8969146265245086 0.9152717073146395 0.7774742620043735 0.8389340307077141 1.0 13.878103682926591 NTS(ph)ASDEDER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NTSASDEDER 10 0 Q32MZ4-2;Q32MZ4;C9JTC6;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 NT(0.002)S(0.998)ASDEDER;NT(0.08)S(0.856)AS(0.064)DEDER 112.43 0.0014524000000000002 17776300.0 9798.6 11974.5 11872.400000000001 12377.400000000001 20431.3 21275.4 20169.0 17483.7 24686.0 21742.3 True False 11457.309448828368 13163.24922328645 12155.48304232773 11683.934406072229 16427.93343231424 20159.68057079884 18258.446309085164 17024.771400511407 25046.986048676317 25684.006878047905 0.4460873065183968 0.5125076194609286 0.47327051032356676 0.45491088915952893 0.6396172338030005 0.7849118195038834 0.7108877674647658 0.6628549618970263 0.9751977628570078 1.0 14.648582669710265 -7.295243555832813 0.3784688006433386 1.0183768630130268 0.39420134310821436 0.8428003109488607 0.07704911441451029 0.5292382989512332 0.1865620586217516 0.0950548138680567 0.11624439778218648 5.067064635252143e-08 7.295243555832813 -0.6241755199048125 down NTS(ph)ASDEDER ddPTM_PC-9_Lapatinib_30min_R1 2 NTSASDEDER 10 0 Q32MZ4-2;Q32MZ4;C9JTC6;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 NT(0.073)S(0.91)AS(0.017)DEDER;NT(0.004)S(0.764)AS(0.232)DEDER 111.72 0.0015550999999999998 14943200.0 872.36 3445.15 3559.72 4448.4 7590.200000000001 6631.799999999999 10718.8 13147.5 11231.300000000001 9574.7 True False 859.9199864287692 3437.172966844386 3267.0535625165708 4775.5501754273855 7143.759358907351 6348.173373480871 11273.767016508808 13758.380847308481 9966.312723167826 11229.6741375142 0.07657568473479509 0.3060794930248295 0.29093039766866874 0.4252616876454174 0.6361501920205045 0.565303435856074 1.0039264611292067 1.2251807736207416 0.8874979452764397 1.0 13.45502844379614 -6.664893729249201 0.7683778678462537 1.085834160976324 0.18405077733531314 0.8781978951737035 0.1242863214443138 0.214191241762113 0.2801258813973015 0.08455880769661817 0.09149635220571632 2.1632478001811734e-07 6.664893729249201 -0.9017833836410108 down NTSAS(ph)DEDER ddPTM_PC-9_AZD4547_30min_R2 1 NTSASDEDER 10 0 Q32MZ4-2;Q32MZ4;C9JTC6;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 NT(0.07)S(0.07)AS(0.86)DEDER 84.169 0.032457 0.0 2998.1 3661.6 4663.0 5712.7 5358.1 5489.7 4900.8 4950.7 6017.8 5442.3 True False 3951.433435646017 4845.140593509374 4601.165573249923 4395.725275335175 4614.22030253829 5146.428191171878 5336.961705892404 4185.683070768463 6335.888622417805 5251.766733507195 0.752400789325843 0.9225734575369705 0.8761176584431442 0.8369993372496298 0.8786034370298196 0.9799422655878377 1.0162221546973231 0.7970047572873086 1.2064299394704114 1.0 12.358587122468267 -7.0153079570568 0.5324527701969036 1.0394726420094904 0.8285461649407687 0.36670141441385584 0.09895062632594749 1.1124738820207107 0.6731726087591209 0.0872172503467106 0.08801352880610813 9.653660977095304e-08 7.0153079570568 -0.2109264770687217 NTSAS(ph)DEDER ddPTM_PC-9_Lapatinib_30min_R1 1 NTSASDEDER 10 0 Q32MZ4-2;Q32MZ4;C9JTC6;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 NT(0.001)S(0.025)AS(0.974)DEDER 92.295 0.0075236 696160.0 680.11 3101.1 3366.9 3022.6 3980.1 2747.3 3071.3 5098.6 5606.0 3241.8 True False 670.4115066831007 3093.9195934810145 3090.0864786098477 3244.892087098015 3745.998343177669 2629.8043832690946 3230.3168860136852 5335.499569354405 4974.593246202918 3802.1408105730225 0.1763247444226198 0.8137309341299036 0.8127227876508181 0.8534381678013067 0.9852339852224221 0.6916641214223614 0.8496047482067984 1.403288261843803 1.3083663898952744 1.0 11.892596247199219 -4.969430152601223 0.38121491215395475 1.1724625676093776 1.3241971353025672e-12 0.5644517243850831 0.21109343584816337 4.565678230942147 0.5870443012990534 0.2041291466517968 2.4327037380683074 1.072926192228054e-05 4.969430152601223 -1.1724625676080533 NTSGLPAEPESVS(ph)SPPTLHMK ddPTM_PC-9_AZD4547_30min_R2 2 NTSGLPAEPESVSSPPTLHMK 21 0 Q8IWI9-3;Q8IWI9 Q8IWI9-3 MGA MAX gene-associated protein 1 NTSGLPAEPES(0.135)VS(0.432)S(0.432)PPTLHMK;NTSGLPAEPES(0.125)VS(0.512)S(0.363)PPTLHMK 97.542 0.00019813 25864000.0 46994.0 37194.0 60493.0 91642.0 72567.0 67871.0 47794.0 64660.0 54557.0 75407.0 True False 61937.11446407688 49216.23313168768 59690.823294575974 70515.35275478594 62492.32464759829 63627.01564075026 52047.57341075361 54668.282738984104 57440.77163967705 72767.02388210433 0.8511700927115853 0.6763535253472347 0.8203004618037677 0.9690564350829229 0.8588000623585637 0.8743935404564225 0.7152631870045977 0.7512782552101699 0.7893791524680387 1.0 16.15099718629368 -11.969214339320978 2.1743400891058977 2.7635832106012264 0.81127734071695 0.33144080255596253 0.08019459697352524 4600571.1416118285 371235.15267779643 40048541.122164205 0.02208319582439764 1.0734594922641036e-12 11.969214339320978 -1.9523058698842763 NTSGLPAEPESVS(ph)SPPTLHMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NTSGLPAEPESVSSPPTLHMK 21 0 Q8IWI9-3;Q8IWI9 Q8IWI9-3 MGA MAX gene-associated protein 1 NTSGLPAEPES(0.001)VS(0.585)S(0.397)PPT(0.017)LHMK;NTSGLPAEPES(0.085)VS(0.454)S(0.454)PPT(0.006)LHMK;NTSGLPAEPES(0.005)VS(0.495)S(0.495)PPT(0.005)LHMK 85.93700000000001 0.00031576 41642000.0 67996.0 75622.0 84335.0 95651.0 105162.0 95525.0 93035.0 103255.0 95256.0 78053.0 True False 79506.37981778345 83129.25239161296 86345.86624226876 90291.98457472594 84556.26101173343 90515.50083784842 84222.05128492937 100544.66565771552 96648.93879335308 92203.39103279219 0.8622934463387248 0.9015856299910704 0.9364716988723311 0.979269672875844 0.9170623776913036 0.9816938381979523 0.9134376766574209 1.0904660287597965 1.0482145798626845 1.0 16.492532190249932 -6.194613287135844 0.39053687029910805 1.0416815024696644 0.8508315838975774 0.5458436351357583 0.045044413536503264 1.6714931048673345 0.43026555052239274 0.04697925900555147 0.1349270138497437 6.388320741762328e-07 6.194613287135844 -0.190849918572087 NTSGLPAEPESVS(ph)SPPTLHMK ddPTM_PC-9_Lapatinib_30min_R1 2 NTSGLPAEPESVSSPPTLHMK 21 0 Q8IWI9-3;Q8IWI9 Q8IWI9-3 MGA MAX gene-associated protein 1 NT(0.002)S(0.001)GLPAEPES(0.002)VS(0.497)S(0.497)PPT(0.002)LHMK;NTSGLPAEPES(0.001)VS(0.499)S(0.499)PPT(0.002)LHMK 98.29899999999999 0.00014916 7664200.0 29366.0 22845.8 26482.0 23749.0 33475.0 25355.0 23765.0 21281.1 29726.0 19940.7 True False 28947.23545493514 22792.901953741766 24304.752183476186 25495.58068434156 31506.06631438217 24270.6257553918 24995.435416961936 22269.89759647511 26377.94485134283 23387.423425687422 1.2377265732975584 0.974579436942478 1.0392231645655 1.090140637567568 1.3471371232701799 1.0377639859521386 1.0687554144809455 0.9522168043537074 1.127868785339166 1.0 14.513445309399822 -6.9327002482623845 24.999999999515406 1.036066793307752 1.1277630553403781 0.18243081238355974 0.10524483404400628 108.95577080409649 40472.67650893241 0.038229681144663866 0.03371540854913932 1.1676152315761024e-07 6.9327002482623845 0.09169626203262604 NTSGLPAEPESVSS(ph)PPTLHMK ddPTM_PC-9_AZD4547_30min_R2 1 NTSGLPAEPESVSSPPTLHMK 21 0 Q8IWI9-3;Q8IWI9 Q8IWI9-3 MGA MAX gene-associated protein 1 NTSGLPAEPES(0.005)VS(0.233)S(0.763)PPTLHMK 102.78 8.999299999999999e-05 11293000.0 38488.0 34124.0 45530.0 64427.0 52703.0 48947.0 36616.0 50796.0 38674.0 50123.0 True False 50726.38339986787 45153.91566880979 44926.242451226455 49574.35053722744 45386.09816999969 45886.336352312486 39874.75306540895 42946.64537595791 40718.22868546419 48368.209026253804 1.0487546349366392 0.9335453302457544 0.9288382463539412 1.0249366585047412 0.9383456423901193 0.9486879352387395 0.8244000319252117 0.8879105974886703 0.8418386685221841 1.0 15.561771498338429 -7.075492253946163 5.395999963632288 0.8791425785119563 0.9703806377635654 0.33368294387785624 0.05687494871495302 0.2391510118791566 12.410539705138723 0.020923878007234498 0.01628114904757739 8.404419970460945e-08 7.075492253946163 0.0912380592516091 NTSGLPAEPESVSS(ph)PPTLHMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NTSGLPAEPESVSSPPTLHMK 21 0 Q8IWI9-3;Q8IWI9 Q8IWI9-3 MGA MAX gene-associated protein 1 NTSGLPAEPESVS(0.479)S(0.521)PPTLHMK 98.37700000000001 0.00018089 9693200.0 13127.0 18847.0 19705.0 26259.0 25162.0 19449.0 23970.0 17677.0 21856.0 17236.0 True False 15349.141829931825 20718.005604516246 20174.84193162866 24787.793362826655 20231.686726928347 18429.06020199228 21699.388072228227 17212.99748032968 22175.602652510297 20360.750359899084 0.7538593400841589 1.0175462710510308 0.9908692742170949 1.2174302481330317 0.9936611553754457 0.9051267697033747 1.06574599111856 0.8454009393598299 1.0891348432907266 1.0 14.313503109949181 -4.760726567588904 24.825132319932766 1.0122806679516092 0.753859024471901 0.4001939632583904 0.09548085439398592 16.7583799120701 583201.3845241544 0.02373330131730042 0.13822080264457384 1.7348959468778554e-05 4.760726567588904 -0.2584216434797082 NTSGLPAEPESVSS(ph)PPTLHMK ddPTM_PC-9_Lapatinib_30min_R1 3 NTSGLPAEPESVSSPPTLHMK 21 0 Q8IWI9-3;Q8IWI9 Q8IWI9-3 MGA MAX gene-associated protein 1 NTSGLPAEPES(0.005)VS(0.107)S(0.887)PPT(0.001)LHMK;NTSGLPAEPES(0.002)VS(0.241)S(0.756)PPTLHMK;NTSGLPAEPES(0.001)VS(0.267)S(0.731)PPT(0.001)LHMK 101.42 0.00011810000000000001 22618900.0 104144.0 86411.0 105342.0 80429.0 95065.0 100679.0 85262.0 84388.0 102827.0 78707.0 True False 102658.88746232938 86210.92063857596 96681.18739187937 86344.01696327863 89473.46360498108 96373.193864212 89676.44916982988 88308.97455354029 91245.54044368655 92311.40007951492 1.1120932774706198 0.9339141272293113 1.0473374611218162 0.9353559461659543 0.969256923065956 1.0440009985895387 0.9714558450265585 0.9566421317136666 0.988453651066821 1.0 16.494221205346626 -4.747404285190687 24.95274172887781 0.9832281449817424 1.1120936103948595 0.5196730969969242 0.03725073082347792 562.4307816456371 999877.2532625245 0.008886246053241764 0.1803067848136795 1.7889397527675905e-05 4.747404285190687 0.12886546541311716 NTSLPPLWS(ph)PEAER ddPTM_PC-9_AZD4547_30min_R2 2 NTSLPPLWSPEAER 14 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 NTSLPPLWS(1)PEAER;NTS(0.063)LPPLWS(0.937)PEAER 184.92 6.220599999999999e-06 51822000.0 54022.0 50755.0 64064.0 85821.0 83990.0 69122.0 55972.0 70053.0 58128.0 62979.0 True False 71199.8722725957 67160.56118187896 63214.46950132598 66036.29437123258 72329.43827293103 64799.79041298838 60953.399567868386 59227.91850779553 61200.52740933604 60774.12437931567 1.1715491255490373 1.105084801595873 1.0401543444176857 1.0865856982006619 1.1901354237782846 1.0662398031199416 1.0029498604938145 0.97455815468653 1.0070161937234838 1.0 15.891169581909265 -7.14061699102029 3.4958206062296493 0.993504187246517 1.112837742499209 0.6655705099974856 0.040611629932164835 0.1652388953555384 3.7029346632518614 0.017527045144049545 0.013218116275955875 7.23407503229899e-08 7.14061699102029 0.11933355525269207 NTSLPPLWS(ph)PEAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NTSLPPLWSPEAER 14 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 NTSLPPLWS(1)PEAER;NTSLPPLWS(0.999)PEAER;NTSLPPLWS(1)PEAER;NTSLPPLWS(1)PEAER 187.5 4.3037e-06 44308700.0 90431.0 88860.0 91185.0 107152.0 111119.0 93625.0 100656.0 89292.0 83226.0 72188.0 True False 105739.1822063355 97681.4335447189 93359.19622103825 101148.62083147111 89346.02962441597 88715.14018260711 91121.13499366726 86948.17961269438 84443.02280187698 85275.11296010627 1.23997704061445 1.1454858299679602 1.094800029930349 1.1861446712922075 1.0477386252916976 1.0403403420187807 1.0685548436188634 1.0196196357238578 0.9902422860627748 1.0 16.37983714046262 -1.5229026473797207 0.21732856030512732 0.9779805934347501 2.2832443300764105 0.7986591176781415 0.03536150697268681 22.557108396199173 0.28642441134689195 0.05746622100131621 10.285845945191536 0.02999834894690268 1.5229026473797207 1.3052637366416604 NTSLPPLWS(ph)PEAER ddPTM_PC-9_Lapatinib_30min_R1 4 NTSLPPLWSPEAER 14 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 NTSLPPLWS(1)PEAER;NTSLPPLWS(1)PEAER;NTSLPPLWS(1)PEAER;NTSLPPLWS(1)PEAER 183.88 6.9858e-06 43337200.0 117202.0 118077.0 119324.0 112400.0 112805.0 112361.0 101159.0 107000.0 113795.0 95694.0 True False 115530.67798778528 117803.59996112944 109513.6413239599 120666.27095540821 106170.03168316306 107555.58195628389 106396.5180452115 111971.61062270476 100978.20878552644 112234.58039576026 1.029367932596196 1.049619462608866 0.9757566780023963 1.075125603266981 0.9459654173320516 0.9583105454399407 0.9479833904135191 0.9976569630132868 0.8997067430506557 1.0 16.776157725063428 -6.279309270293406 24.764643249020672 0.9576409995453056 1.0296417996191034 0.51614807077992 0.03514760924439483 572.5979839383899 793522.0419086467 0.010195511277394077 0.01158334821098527 5.25642811705321e-07 6.279309270293406 0.07200080007379783 NTSPGPVSS(ph)PGR ddPTM_PC-9_AZD4547_30min_R2 3 NTSPGPVSSPGR 12 0 Q9H6K5;Q9H6K5-2;A0A096LNU1 Q9H6K5 PRR36 Proline-rich protein 36 1 NTSPGPVS(0.03)S(0.97)PGR;NTS(0.012)PGPVS(0.205)S(0.783)PGR;NTSPGPVS(0.092)S(0.908)PGR 110.51 0.0011841 5160200.0 32922.1 35550.0 54761.0 85514.0 72651.0 60305.0 51746.0 62630.0 46038.0 59634.0 True False 43390.64297777985 47040.84228185988 54034.83335979824 65800.06847812978 62564.66269754375 56534.11881680607 56351.29375471518 52951.97259422481 48471.47469156024 57546.23181117691 0.7540136271677185 0.8174443538929229 0.9389812618330873 1.1434296635448815 1.0872069417652492 0.982412176044961 0.9792351641653513 0.9201640303395194 0.84230492885454 1.0 15.812433841785092 -5.26362566805094 3.1263572984186387 0.9953925839352133 0.7717536080597609 0.5232795159132153 0.07845534281237554 0.21465130326272028 4.277312055353578 0.023546318423531026 0.0679180284891992 5.4497217896926475e-06 5.26362566805094 -0.22363897587545245 NTSPGPVSS(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NTSPGPVSSPGR 12 0 Q9H6K5;Q9H6K5-2;A0A096LNU1 Q9H6K5 PRR36 Proline-rich protein 36 1 NTSPGPVS(0.239)S(0.761)PGR;NTSPGPVS(0.178)S(0.822)PGR 106.58 0.0016545000000000002 2524300.0 30304.0 30851.0 33156.0 40243.0 45482.0 36026.0 38459.0 36280.0 34094.0 29935.0 True False 35433.86866871747 33913.68339284398 33946.56478483023 37988.31517956634 36570.12859526885 34136.7331398516 34815.885100952255 35327.68844183746 34592.560250488954 35361.9785346704 1.002032978272881 0.9590437186537385 0.959973570244311 1.074270070672685 1.034165228040448 0.9653513336755885 0.9845570452687558 0.999030311813596 0.978241650607104 1.0 15.109911376628963 NTSPGPVSS(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 2 NTSPGPVSSPGR 12 0 Q9H6K5;Q9H6K5-2;A0A096LNU1 Q9H6K5 PRR36 Proline-rich protein 36 1 NT(0.01)S(0.135)PGPVS(0.209)S(0.646)PGR;NTSPGPVS(0.187)S(0.813)PGR 88.28200000000001 0.0081198 6379800.0 44237.0 36950.0 36079.0 38030.0 43287.0 34821.0 31073.0 34436.0 37170.0 28626.0 True False 43606.17226792772 36864.444545201244 33112.72388896749 40826.853064361 40740.943765516386 33331.787001715566 32681.807898643317 36036.02227479862 32983.52318254769 33573.96595825265 1.2988090927997473 1.0980068482537964 0.9862619128803941 1.2160271180094395 1.2134683110173958 0.9927867039348816 0.9734270875023021 1.0733323051440333 0.982413672056523 1.0 15.035055346443455 -6.7731457044220456 24.99576433684185 1.0070398873817357 1.1521119853069208 0.48338926304289953 0.08135544483164919 226.41861562123455 483454.37034781236 0.029884951859398563 0.026564630947283025 1.685987287101791e-07 6.7731457044220456 0.14507209792518516 NTTPCEIFS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 NTTPCEIFSR 10 0 P46934-3;P46934-2;P46934;H0YA37 P46934-3 NEDD4 E3 ubiquitin-protein ligase NEDD4 1 NTTPCEIFS(1)R 69.812 0.037408 2862900.0 3514.4 2174.9 1559.7 1178.2 4356.0 4126.8 1436.9 0.0 862.19 1505.5 True False 3464.284011537974 2169.8641526754577 1431.4674866161097 1264.8487583599817 4099.788644225505 3950.3063840406617 1511.2956511943034 0.0 765.0810829367981 1765.7236690473455 1.9619627194594083 1.2288809346063514 0.8106973428002039 0.7163344868353048 2.3218744337484294 2.2372166456668476 0.8559072281166663 0.0 0.43329604532603877 1.0 10.78604386746267 -7.515493635544959 22.366121632469333 0.41557879997670516 1.5000756010578626 0.4313728376299444 0.5576447610267312 88.48831665372347 268001.4733727054 0.27393992356931696 0.16719061212315933 3.0514507469065105e-08 7.515493635544959 1.0844968010811575 NTVELLVEDK ddPTM_PC-9_Lapatinib_30min_R1 2 NTVELLVEDK 10 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 122.7 0.0023815999999999998 6815500.0 44419.0 42960.0 44090.0 34628.0 40099.0 34910.0 46153.0 41697.0 39587.0 40946.0 False True 43785.57691455304 42860.52875945451 40465.09039232175 37174.65863562168 37740.45565766727 33416.98067918472 48542.57651163662 43634.39484238234 35128.29519040933 48023.46154288455 0.9117538700423102 0.892491448605395 0.8426108633628328 0.7740936917349246 0.7858753710197537 0.6958469799046793 1.010809611637189 0.9086057822678439 0.7314819478191936 1.0 15.551451776678096 -9.737376495847602 8.927044279712566 1.0 0.8403247779660996 0.22158611325134636 0.09034819725645368 0.0 0.0 0.0908598229179594 0.02203674394209782 1.8307266521769548e-10 9.737376495847602 -0.1596752220339004 NTVS(ph)Y(ph)S(ph)GKR ddPTM_PC-9_AZD4547_30min_R2 1 NTVSYSGKR 9 1 C9J5I7;C9JZ23;Q9BYH8-3;Q9BYH8-2;Q9BYH8 C9J5I7 NFKBIZ NF-kappa-B inhibitor zeta 3 NT(0.042)VS(0.959)Y(1)S(1)GKR 66.92 0.036767 6234500.0 0.0 0.0 0.0 441.77 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 339.92675177846183 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NVAEALGHS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 NVAEALGHSPK 11 0 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 NVAEALGHS(1)PK 63.461999999999996 0.028745 9716700.0 69675.0 72408.0 57983.0 47386.0 60576.0 68229.0 67492.0 68510.0 63546.0 64074.0 True False 91830.20066996988 95812.46998438571 57214.107534580864 36461.88980640198 52166.068017871905 63962.62984415647 73498.65725067114 57923.35370318282 66904.91182826989 61830.78876260773 1.4851856576266798 1.5495915853871245 0.9253336190526036 0.5897044261620736 0.8436908061800341 1.0344786331245701 1.1887064474118365 0.9368043795393414 1.082064666603942 1.0 15.916037789427968 -5.262336593745766 24.99033156886231 0.9427047602964768 1.5173886671729393 0.6924826217675502 0.1511511991478484 44.61118311919562 1242607.425470969 0.04395936405072031 0.10095005227543781 5.465921702200632e-06 5.262336593745766 0.5746839068764625 NVAEALGHS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NVAEALGHSPK 11 0 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 NVAEALGHS(1)PK 57.788000000000004 0.042416 6491600.0 71649.0 113450.0 70361.0 70219.0 69050.0 47434.0 101800.0 54448.0 48914.0 59905.0 True False 83777.76056774477 124712.56623507004 72038.67308557831 66284.85708306951 55520.14817957245 44946.47753721535 92156.76703182436 53018.79769242468 49629.2747138035 70765.30229228093 1.1838819005070969 1.7623406132001174 1.0179942818309176 0.936685846536684 0.7845673851608569 0.6351485273329796 1.3022874777131674 0.7492202530760328 0.7013221608072895 1.0 16.110754529672057 -5.43598633488174 5.2162006704537776 0.873435955410844 1.4692823691118997 0.5364828521688647 0.2197452520208934 0.15599206977114025 6.9538955141499565 0.05687806329089587 0.12060239679496187 3.664491048232819e-06 5.43598633488174 0.5958464137010557 NVAEALGHS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 NVAEALGHSPK 11 0 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 NVAEALGHS(1)PK 70.134 0.018691 13385000.0 49677.0 68164.0 54338.0 52423.0 64670.0 63181.0 65466.0 62035.0 52361.0 50916.0 True False 48968.59687035391 68006.1704459837 49870.53939074573 56278.362298001484 60866.2377461119 60478.895912104555 68855.5091524019 64917.37256990163 46463.552794225965 59716.762758694545 0.8200142574410442 1.138812073936179 0.8351179314971283 0.9424215194888065 1.0192487826586012 1.0127624659844616 1.1530348594185438 1.0870879393148265 0.778065498660358 1.0 15.865848338749885 -6.261645760462987 8.564533745599975 1.0202208455148598 0.9415807475726614 0.07685536660716008 0.1209247129053557 0.29693972947186853 311.9972619572813 0.03633944694133059 0.04395314484165261 5.474623276045039e-07 6.261645760462987 -0.0786400979421984 NVAEALGHS(ph)PKDPGGGGGPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NVAEALGHSPKDPGGGGGPVR 21 1 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 NVAEALGHS(1)PKDPGGGGGPVR 47.714 0.028031999999999998 8422700.0 8072.2 7163.8 6846.9 10933.0 11102.0 9798.2 7185.2 9616.4 6557.1 5237.1 True False 9438.664026782639 7874.974720095159 7010.156063012849 10320.459455264241 8926.642796373839 9284.365143254703 6504.565839656835 9363.979689418018 6652.985182685544 6186.5447731392105 1.525676184833173 1.2729197005551123 1.1331294478704173 1.6682105817893202 1.4429125018429685 1.5007351411349408 1.0514052800358629 1.5136041252097003 1.0753959482474817 1.0 12.59491816414507 -8.386561640485304 5.19634962456641 1.0055440386860364 1.379210489966666 0.38062513071593096 0.17951524382172276 0.2367780111783217 8.438245232487034 0.17181532770239247 0.044758166860926214 4.106183556643062e-09 8.386561640485304 0.3736664512806296 NVAEALGHS(ph)PKDPGGGGGPVR ddPTM_PC-9_Lapatinib_30min_R1 1 NVAEALGHSPKDPGGGGGPVR 21 1 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 NVAEALGHS(1)PKDPGGGGGPVR 51.166000000000004 0.017851 15279000.0 12575.0 13572.0 9507.3 6515.9 8093.9 8484.9 9570.3 5831.0 7976.3 6450.4 True False 12395.678194027429 13540.574867861185 8725.646493239292 6995.101022405199 7617.832715219651 8122.020606267958 10065.80330616246 6101.929547112058 7077.925099837376 7565.343045382271 1.6384819722872308 1.7898163753626575 1.1533708968511673 0.9246244328173412 1.0069381744519064 1.073582593353182 1.3305151195102007 0.8065634975847591 0.9355722612152525 1.0 12.88518978662174 -5.345559649276442 4.200389895556872 1.020573176508284 1.716064811549942 0.8107862916078672 0.13347526391896575 0.0877723715374507 2.8106975560210947 0.037011400305489335 0.08396380171116076 4.5127403970741864e-06 5.345559649276442 0.695491635041658 NVALLSQLYHS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 2 NVALLSQLYHSPAR 14 0 Q15717;Q15717-2 Q15717 ELAVL1 ELAV-like protein 1 1 NVALLSQLYHS(1)PAR;NVALLSQLYHS(1)PAR 181.6 1.6648e-05 98542000.0 134457.0 151960.0 225317.0 256280.0 201984.0 233720.0 169731.0 269200.0 181432.0 227241.0 True False 177211.52912066167 201078.09826023708 222329.14936048738 197198.60548652997 173942.0080976271 219105.45145284638 184836.7301874842 227601.32560059617 191022.1251192311 219285.36175677693 0.8081320508626473 0.9169700004109957 1.0138804869569293 0.8992784739788297 0.7932221590356635 0.9991795608129552 0.8429050106522759 1.03792302312018 0.8711120687166781 1.0 17.74244998354925 -14.522878707648978 0.08665607054330857 1.2822827929046483 0.8375107137095102 0.12486848987239141 0.07977320819557127 522.1140869347289 3.15250309447964 27.492079692598026 2.107676650856057 3.0000002599482336e-15 14.522878707648978 -0.44477207919513806 NVALLSQLYHS(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NVALLSQLYHSPAR 14 0 Q15717;Q15717-2 Q15717 ELAVL1 ELAV-like protein 1 1 NVALLSQLYHS(1)PAR;NVALLSQLYHS(1)PAR 162.09 0.00024496 71397000.0 75328.0 95319.0 87505.0 115890.0 113052.0 76854.0 94732.0 66069.0 63803.0 57832.0 True False 88079.54260418242 104781.64037867494 89591.45106456039 109397.05902044916 90900.27215057235 72823.6409462653 85758.29915971303 64334.75875589197 64735.99817158287 68316.48380213989 1.2892868265773287 1.5337680534341676 1.311417773257149 1.6013274239536095 1.3305759765657765 1.0659746651654256 1.2553090321230322 0.9417164815188688 0.9475897260619132 1.0 16.059946101993802 -7.019749055028579 1.0868672818005307 0.9756122870362107 1.4394839110767947 0.7085946922784547 0.11994122510445517 0.2700379597581316 0.6538650528485014 0.07303436156876271 0.051443027352491365 9.555445613474919e-08 7.019749055028579 0.463871624040584 NVALLSQLYHS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 2 NVALLSQLYHSPAR 14 0 Q15717;Q15717-2 Q15717 ELAVL1 ELAV-like protein 1 1 NVALLSQLYHS(1)PAR;NVALLSQLYHS(1)PAR 171.33 1.0825e-05 65456000.0 227980.0 254920.0 287940.0 231360.0 250630.0 236066.0 256730.0 214580.0 218637.0 182324.0 True False 224728.96339358858 254329.7484022375 264266.68468054314 248374.9861943345 235888.4361575385 225970.00747672335 270022.22321046254 224550.170162803 194011.79871032241 213838.46046854067 1.0509286444598682 1.189354561592786 1.235823921017339 1.16150754943765 1.1031151067992362 1.0567322968076056 1.2627392781392919 1.0500925309263447 0.9072820590141917 1.0 17.70616183047501 -7.993808240932116 8.73665448903433 0.9615976742702809 1.1515351517559647 0.5760587512463688 0.06847148821491662 0.0827068380824419 64.49267528198993 0.03957189955329176 0.018022649968256664 1.014359168613054e-08 7.993808240932116 0.1899374774856838 NVALLSQLYHS(ph)PARR ddPTM_PC-9_AZD4547_30min_R2 2 NVALLSQLYHSPARR 15 1 Q15717;Q15717-2 Q15717 ELAVL1 ELAV-like protein 1 1 NVALLSQLY(0.001)HS(0.999)PARR;NVALLSQLY(0.217)HS(0.783)PARR 68.625 0.010326 18931600.0 25505.1 21514.8 37098.0 77830.0 53034.0 43121.0 31550.0 41173.0 31569.0 37236.0 True False 33615.191260963664 28469.038355154964 36606.05628059739 59887.49596151321 45671.144533475606 40424.63705330392 34357.888879551334 34810.65891141654 33237.67289060917 35932.37897375631 0.9355125438678847 0.7922948373651436 1.0187484749432567 1.666672167886597 1.2710303586309197 1.1250197790363001 0.9561818577235054 0.9687824715652967 0.9250061877307022 1.0 15.13299683451164 -7.237104747339517 5.425687106017717 0.9591918854407271 1.1453759081706658 0.1296902443780541 0.218037933198575 0.44196478529428673 41.198416817024906 0.09949298672472275 0.07373291350730835 5.792889610671851e-08 7.237104747339517 0.18618402272993873 NVALLSQLYHS(ph)PARR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NVALLSQLYHSPARR 15 1 Q15717;Q15717-2 Q15717 ELAVL1 ELAV-like protein 1 1 NVALLSQLYHS(1)PARR 80.541 0.0044653 9261100.0 12844.0 9745.0 11081.0 16344.0 20946.0 15666.0 16600.0 18073.0 13142.0 8865.0 True False 15018.235519436623 10712.419197538647 11345.213064926524 15428.298667962941 16841.781662119105 14844.44738158317 15027.527826407535 17598.60289992637 13334.176887778667 10472.154324698615 1.4341113636967762 1.0229432135347134 1.083369544905273 1.4732688413094945 1.6082442198543332 1.4175161023527398 1.4349986984975054 1.6805140904407796 1.2732983562255153 1.0 13.354270642624849 -5.768588565180669 24.997574893179916 1.4501997854008633 1.1644215467570533 0.19918792870538804 0.20326002078239394 193.46279682815978 676456.743146978 0.05400704575512018 0.08202242923702827 1.7037718356295042e-06 5.768588565180669 -0.2857782386438099 NVDAAVS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 NVDAAVSPR 9 0 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 NVDAAVS(1)PR;NVDAAVS(1)PR 100.09 0.0039328 62020000.0 86852.0 92210.0 121718.0 159761.0 120928.0 110255.0 104136.0 118979.0 106318.0 101632.0 True False 114469.12936617427 122015.07923517012 120103.93979087152 122930.56973284476 104139.2345692224 103360.73742056156 113403.90226183692 100593.52941542832 111937.75242750107 98073.89461437332 1.1671722614490536 1.2441137339853137 1.2246270045981182 1.2534484351438058 1.0618445915571928 1.0539067284620043 1.1563107869605995 1.025691187353803 1.1413613466421462 1.0 16.581581549404724 -6.264670557688073 24.991840475721535 1.0776626271379806 1.2240589344820303 0.6867645348792517 0.04928740692611499 157.182233449555 1215737.495052101 0.014232279408582842 0.01679650759154692 5.436625806694271e-07 6.264670557688073 0.14639630734404974 NVDAAVS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NVDAAVSPR 9 0 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 NVDAAVS(1)PR 77.67399999999999 0.022713999999999998 17980000.0 42437.0 42876.0 43162.0 54412.0 49599.0 49771.0 60721.0 49618.0 41282.0 42107.0 True False 49620.7459310442 47132.44592238761 44191.14577279656 51363.47204608415 39880.43199940065 47160.92114316197 54969.06729802964 48315.58007461663 41885.67115212897 49740.665781171396 0.9975890984118554 0.9475636319333086 0.8884309262608318 1.0326253426532752 0.8017671531549304 0.9481361055889616 1.1051132194301545 0.9713496857315044 0.842081031572846 1.0 15.602138197775076 -7.013123023871842 24.955532224075206 0.9843021978819533 0.9311225850697479 0.06299733625134463 0.08293531958639688 1725.6840413317736 3281661.9273937936 0.031068380892946352 0.02523130952599004 9.702350869750971e-08 7.013123023871842 -0.0531796128122054 NVDAAVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 NVDAAVSPR 9 0 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 NVDAAVS(1)PR 105.36 0.0026414999999999998 34232000.0 50281.0 39756.0 46474.0 45877.0 41216.0 36064.0 46160.0 41073.0 46138.0 34742.0 True False 49563.983719593874 39663.947424601356 42653.08711482788 49250.94762118562 38791.75591377376 34521.6267892901 48549.93893738539 42981.40152435835 40941.45258532111 40747.10840919491 1.2163803924896268 0.9734174760644088 1.0467758027512666 1.2086979799055326 0.9520124845231985 0.8472166035099566 1.1914940920428532 1.0548331698221622 1.004769520677996 1.0 15.314410062654352 -4.748904073557446 24.837185713639272 1.035583800694439 1.2163808506195986 0.2292680699920644 0.10164600073694528 908.4686118857587 1799901.3697935368 0.02590458946254191 0.4467735397468342 1.7827725006074687e-05 4.748904073557446 0.18079704992515966 NVDLLSDMVQEHDEPILK ddPTM_PC-9_AZD4547_30min_R2 2 NVDLLSDMVQEHDEPILK 18 0 P55209;F8W020;P55209-2;P55209-3;F8W0J6;H0YIV4;B7Z9C2;H0YHC3;F8VV59;F5H4R6;F8VY35;F8VUX1;F8VXI6;F8W118;F8W543;H0YH88 P55209 NAP1L1 Nucleosome assembly protein 1-like 1 0 ; 85.20299999999999 0.0012676999999999999 7090100.0 24718.0 27537.0 28160.0 41136.0 41302.0 39480.0 33169.0 41037.0 32553.0 32040.0 False True 32577.80983366072 36437.79673461535 27786.580000582868 31652.730744864555 35567.93022441472 37011.30935888403 36120.976743132764 34695.674586447465 34273.68512173334 30918.289352217 1.0536743951949827 1.178519170951564 0.8987101350932414 1.0237542699817863 1.1503848036102395 1.1970684709382255 1.1682721618795737 1.1221731639548036 1.10852462538571 1.0 14.916172879557838 -6.261744344964248 24.994873211978557 1.1363391754045415 1.0386573705696425 0.20764664902832475 0.08003868156463982 40.9535503946287 3356591.242110837 0.02461753460069926 0.0296891057340726 5.473380681963909e-07 6.261744344964248 -0.09768180483489908 NVDLLSDMVQEHDEPILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NVDLLSDMVQEHDEPILK 18 0 P55209;F8W020;P55209-2;P55209-3;F8W0J6;H0YIV4;B7Z9C2;H0YHC3;F8VV59;F5H4R6;F8VY35;F8VUX1;F8VXI6;F8W118;F8W543;H0YH88 P55209 NAP1L1 Nucleosome assembly protein 1-like 1 0 ; 105.99 0.00022364 9608900.0 62542.0 75811.0 76459.0 84762.0 90570.0 90946.0 90423.0 93054.0 88906.0 61180.0 False True 73129.12533919366 83337.01506255519 78282.07253237216 80013.05994211182 72823.45866218502 86176.6316587171 81857.47883417144 90611.43109886306 90206.08205637275 72271.44969938655 1.0118674198922897 1.1531111581294677 1.0831673206776233 1.1071185132569852 1.0076379948803373 1.1924021452062914 1.132639225789133 1.2537652347609154 1.2481565325115989 1.0 16.141138213284364 -6.784953103948044 24.996545910091225 1.179205904464247 1.0795613311724956 0.2509393454151486 0.07791537774911521 304.2827541864869 323469.26683713624 0.026443114323126855 0.02333339410947567 1.6407669371758727e-07 6.784953103948044 -0.09964457329175125 NVDLLSDMVQEHDEPILK ddPTM_PC-9_Lapatinib_30min_R1 4 NVDLLSDMVQEHDEPILK 18 0 P55209;F8W020;P55209-2;P55209-3;F8W0J6;H0YIV4;B7Z9C2;H0YHC3;F8VV59;F5H4R6;F8VY35;F8VUX1;F8VXI6;F8W118;F8W543;H0YH88 P55209 NAP1L1 Nucleosome assembly protein 1-like 1 0 ;;; 110.77 0.00018267 15911800.0 131378.0 122549.0 134419.0 130621.0 132974.0 123567.0 128545.0 117336.8 124612.0 116927.0 False True 129504.52562822579 122265.24531988795 123367.58869234529 140227.3040788823 125152.73075694272 118282.32745874568 135200.4311244843 122788.69608704819 110576.88433746666 137137.67615456632 0.9443395080011616 0.8915510948434344 0.8995893189359508 1.0225293880642523 0.9126064715861489 0.8625078882438625 0.9858737213258699 0.895368067551724 0.8063202428254415 1.0 17.065265454993067 -6.499936394643662 24.896936135327284 0.9059203151285218 0.9375190064372777 0.048408319940980715 0.06163172212774558 2505.623324700834 2719093.4744894067 0.019280177368364234 0.021700402077191087 3.162740830978763e-07 6.499936394643662 0.03159869130875592 NVFEVGPGDS(ph)PTFPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NVFEVGPGDSPTFPR 15 0 Q16584;Q16584-2 Q16584 MAP3K11 Mitogen-activated protein kinase kinase kinase 11 1 NVFEVGPGDS(0.954)PT(0.046)FPR 98.40799999999999 0.0022619 4159400.0 18716.0 22567.0 29328.0 32687.0 36645.0 26588.0 31572.0 30771.0 28532.0 23017.0 True False 21884.249142150078 24807.30261989272 30027.29074705939 30855.65336268381 29464.675308333557 25193.67847450104 28581.271598514402 29963.29385456948 28949.226522759145 27189.799897528268 0.8048698123791452 0.9123753287403878 1.1043586514143147 1.1348245841812463 1.0836665006501975 0.9265856523199831 1.0511762391128383 1.102004941834579 1.0647090685426788 1.0 14.730777913482703 -5.0452403032575575 3.4249163842402393 1.0602314593827797 0.8156123071088807 0.6815838006925852 0.056714496678707205 0.1410321488789488 3.246164281372963 0.01597031042687118 0.06299763664860436 9.010724194251281e-06 5.0452403032575575 -0.24461915227389908 NVFEVGPGDS(ph)PTFPR ddPTM_PC-9_Lapatinib_30min_R1 1 NVFEVGPGDSPTFPR 15 0 Q16584;Q16584-2 Q16584 MAP3K11 Mitogen-activated protein kinase kinase kinase 11 1 NVFEVGPGDS(0.984)PT(0.016)FPR 124.2 0.00064795 0.0 19740.0 17658.0 14458.0 17945.0 15733.0 15397.0 13527.0 12202.0 16312.0 9351.4 True False 19458.50398012734 17617.11398590429 13269.31904949394 19264.735162765133 14807.615872268116 14738.506202160035 14227.361871880665 12768.949465591031 14474.770787024961 10967.777030042747 1.7741520389069672 1.6062611354741978 1.2098458067798834 1.7564849385609773 1.3501018330065744 1.3438006773650277 1.297196490492952 1.1642240201104146 1.3197542899874712 1.0 13.420983526738256 -1.5228787452807093 0.11766570963971508 0.859098224982436 3.5011998204734103 0.6208528566665777 0.14840006738297332 65.96635086479417 0.537576162987516 1.0917689326466 28.48753346247346 0.029999999999974318 1.5228787452807093 2.642101595490974 NVFSSSGTSFS(ph)GR ddPTM_PC-9_AZD4547_30min_R2 1 NVFSSSGTSFSGR 13 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 NVFSSSGTS(0.001)FS(0.999)GR 111.81 0.00052495 5295800.0 9529.5 13445.0 10667.0 15866.0 14563.0 14242.0 8742.1 12554.0 12574.0 14767.0 True False 12559.682774086497 17790.83331869496 10525.548610306016 12208.338827256437 12541.178825677958 13351.44548858223 9520.129964308266 10614.067762220953 13238.635969670238 14250.01182472498 0.8813805159301259 1.2484784951424641 0.7386343772742207 0.8567248208225297 0.8800819943123099 0.9369427655783653 0.6680787413656761 0.7448462424294024 0.9290263146799698 1.0 13.798675495982268 -5.275441590519506 24.96769524958205 0.8339171542488355 1.064929528393566 0.3225392986217208 0.12719679261266637 717.8145792444175 1279953.4839671997 0.032029787511084776 0.06721904023153291 5.30344915405055e-06 5.275441590519506 0.23101237414473053 NVFSSSGTSFS(ph)GR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NVFSSSGTSFSGR 13 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 NVFS(0.001)S(0.006)S(0.017)GT(0.022)S(0.079)FS(0.875)GR 64.407 0.042128 3208100.0 11433.0 13881.0 14075.0 16385.0 27262.0 14125.0 15570.0 20473.0 14679.0 13288.0 True False 13368.381087956926 15259.013943666903 14410.601379734755 15467.001570886729 21920.206801904482 13384.260134358625 14095.096882961772 19935.605442936576 14893.652605060346 15697.009212249883 0.8516514775008411 0.9720968967616347 0.9180475837708485 0.9853470404296089 1.3964575356685172 0.8526630744354537 0.8979479270460016 1.27002572103856 0.9488210399620203 1.0 13.938202084801175 -6.005547542852143 24.898376642301972 1.0681903177767786 0.9250732382751895 0.1471087918532049 0.15826611884252587 477.94364166683306 2145119.757454247 0.04537268825228273 0.06502944666668477 9.873075478293835e-07 6.005547542852143 -0.14311707950158914 NVFSSSGTSFS(ph)GR ddPTM_PC-9_Lapatinib_30min_R1 1 NVFSSSGTSFSGR 13 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 NVFSSSGTSFS(1)GR 146.84 0.00010621 4710600.0 17997.0 20483.0 19808.0 20513.0 15003.0 14658.0 14564.0 13829.0 16046.0 10496.0 True False 17740.359479754403 20435.57287197176 18179.46270109115 22021.594449362023 14120.553037032892 14031.1115094669 15318.052657800712 14471.545825246549 14238.730508129138 12310.219614959116 1.4411082852004278 1.6600494151330076 1.4767780973622806 1.788887212264016 1.1470593928213837 1.1397937606585502 1.2443362618150646 1.175571702040233 1.1566593410589148 1.0 13.587568879356077 -6.277897558974887 24.995626133253804 1.1574981235983552 1.5883783194669199 0.8100530004799864 0.10610369997560691 326.38757098762363 495695.27353920403 0.030905859290828584 0.03514110832312954 5.273542386372229e-07 6.277897558974887 0.43088019586856463 NVFSSSGTSFS(ph)GRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NVFSSSGTSFSGRK 14 1 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 NVFS(0.001)S(0.001)S(0.006)GT(0.007)S(0.024)FS(0.962)GRK 77.13 0.0071012 9466300.0 46152.0 40315.0 41983.0 51364.0 66610.0 44500.0 50441.0 44556.0 31249.0 35678.0 True False 53964.62205644961 44317.20676744693 42984.03394141415 48486.241604334784 53558.248663885905 42166.34166222719 45662.86331878448 43386.45221098428 31705.957507700132 42146.13897310738 1.2804167444824157 1.0515128514079277 1.019880705296431 1.1504313985979333 1.2707747368759061 1.0004793485147643 1.0834411984433747 1.029428869834751 0.7522861709332633 1.0 15.36311285082378 -8.016239559528973 3.737745000858019 0.8747567993349056 1.116536358805615 0.4574167788610749 0.1057311090519176 0.20242389772367247 6.035714118625725 0.07354363798565886 0.027819870152297293 9.632975161633945e-09 8.016239559528973 0.2417795594707094 NVFT(ph)SAEELER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NVFTSAEELER 11 0 B8ZZF5;C9J5M4;Q9H8M9 B8ZZF5 EVA1A Protein eva-1 homolog A 1 NVFT(0.5)S(0.5)AEELER 114.87 0.0034613 1886500.0 7885.3 9851.7 13333.0 14261.0 32137.0 16667.0 16172.0 18447.0 15466.0 15293.0 True False 9220.125548225911 10829.711668382915 13650.909285684083 13462.002404785826 25839.985547384797 15792.953179423372 14640.071084859195 17962.785796212116 15692.160991202616 18065.499840678604 0.5103720145879768 0.599469251550812 0.7556341870456271 0.7451774112816436 1.430349881003578 0.8742051600400187 0.8103883764064876 0.9943143535815597 0.8686258962992061 1.0 14.140949551712119 -5.695244478191512 2.02551541512859 0.9803704458553032 0.5679151571441575 0.49188248925015665 0.17164936976945075 0.28811210611149707 2.398161030313206 0.05330512440530846 0.11209866493775601 2.0172304807343314e-06 5.695244478191512 -0.4124552887111457 NVFT(ph)SAEELER ddPTM_PC-9_Lapatinib_30min_R1 1 NVFTSAEELER 11 0 B8ZZF5;C9J5M4;Q9H8M9 B8ZZF5 EVA1A Protein eva-1 homolog A 1 NVFT(0.653)S(0.347)AEELER 81.709 0.036077 1686100.0 33885.0 26406.0 16456.0 12112.0 15881.0 12283.0 7624.6 11124.0 18442.0 4680.6 True False 33401.793686252066 26344.858529379788 15103.051201996976 13002.756884447559 14946.910803247301 11757.684723071492 8019.364480545677 11640.861650158551 16364.8677571306 5489.635473492535 6.08451942711629 4.7990178321656485 2.7511938224175627 2.368601147969327 2.722751059778109 2.1417969881324725 1.460819123467904 2.1205163268796374 2.981048165429313 1.0 12.422494638255984 -5.006612188989775 1.2280835522803284 2.0929803484042284 7.146144997770972 0.8653677706513618 0.5307228205695789 0.3423755006374806 0.5865359236785693 0.16318623087307052 1.9925944072293196 9.848901884815381e-06 5.006612188989775 5.053164649366744 NVFTS(ph)AEELER ddPTM_PC-9_AZD4547_30min_R2 2 NVFTSAEELER 11 0 B8ZZF5;C9J5M4;Q9H8M9 B8ZZF5 EVA1A Protein eva-1 homolog A 1 NVFT(0.356)S(0.644)AEELER;NVFT(0.219)S(0.781)AEELER 91.20200000000001 0.011554 1396300.0 14160.2 18482.3 22023.0 26735.0 25345.0 17897.7 25724.0 27531.0 26989.0 22486.0 True False 18662.84904954295 24456.342033924593 21730.96063042744 20571.658801632493 21826.28423654521 16778.55398967829 28013.38616600884 23276.71654944281 28415.58344086447 21698.771984205716 0.8600877995827332 1.1270841525836615 1.0014834317004278 0.9480563608210808 1.00587647321389 0.773249011598039 1.2910125138141209 1.0727204547052553 1.309547999377469 1.0 14.40532577694603 -7.274488592406601 24.99226091832715 1.1743802729225732 0.9650005435814891 0.4244389716724368 0.12245489443843485 781.5393836412376 1496822.6808532358 0.04861912159605939 0.03300409943782257 5.315099604712432e-08 7.274488592406601 -0.20937972934108406 NVFTS(ph)AEELER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NVFTSAEELER 11 0 B8ZZF5;C9J5M4;Q9H8M9 B8ZZF5 EVA1A Protein eva-1 homolog A 1 NVFT(0.22)S(0.78)AEELER;NVFT(0.24)S(0.76)AEELER 85.67200000000001 0.011335 1442400.0 13456.8 16612.2 23868.0 21345.6 44532.0 24763.2 23611.3 22114.4 22732.0 20038.9 True False 15734.770456084923 18261.349429794922 24437.103639894063 20149.675235368908 35806.2742756368 23464.57419887785 21374.666732991343 21533.920432143612 23064.412495281114 23671.793942154876 0.6647054504840187 0.7714391851508557 1.0323300253292724 0.8512103174185816 1.5126134657615775 0.9912461326850261 0.9029593103599641 0.9096868824037824 0.9743415539879243 1.0 14.530881422900361 -5.117476316895692 2.0263324483998444 1.029850185977471 0.6454559545068503 0.33365685647449783 0.17388468937390691 0.5003459555870259 3.4473387446432433 0.05036068342923944 0.2744321067354607 7.629984981380793e-06 5.117476316895692 -0.3843942314706206 NVFTS(ph)AEELER ddPTM_PC-9_Lapatinib_30min_R1 2 NVFTSAEELER 11 0 B8ZZF5;C9J5M4;Q9H8M9 B8ZZF5 EVA1A Protein eva-1 homolog A 1 NVFT(0.292)S(0.708)AEELER;NVFT(0.172)S(0.828)AEELER 113.99 0.0015024 3415700.0 54898.0 53897.0 25271.0 19971.9 27223.0 21740.5 18515.8 16820.2 35154.0 12175.2 True False 54115.144452939756 53772.20480792182 23193.315928881006 21440.700150305332 25621.79666247725 20810.70949458078 19474.457525494803 17601.727897159024 31194.586331968847 14279.667097565769 3.7896642886138903 3.7656483474385953 1.62421965234993 1.5014845937101917 1.7942852930265407 1.4573665725112281 1.3637893231288691 1.23264273437856 2.184545768387453 1.0 13.801674725702927 -5.266844825130076 5.692310008091632 1.5234736968055143 3.7997701133051347 0.9006138029130308 0.3001786015558878 0.03873081925501661 5.111858032128492 0.07474793694320483 0.1776257806376998 5.409475707945244e-06 5.266844825130076 2.2762964164996204 NVHS(ph)EDFENR ddPTM_PC-9_AZD4547_30min_R2 2 NVHSEDFENR 10 0 Q9H2P0;A0A669KBJ7 Q9H2P0 ADNP Activity-dependent neuroprotector homeobox protein 1 NVHS(1)EDFENR;NVHS(1)EDFENR 108.32 0.0011585999999999999 20442500.0 69946.0 66329.0 87258.0 121818.0 86658.0 88311.0 70175.0 91628.0 72717.0 84879.0 True False 92187.3730328196 87768.5521157098 86100.90190663558 93734.74216933854 74627.03252596305 82788.8992095341 76420.43905301158 77468.9980019739 76560.67216530218 81907.41204515696 1.1255070906402844 1.071558115733427 1.0511979289391622 1.1443987769710142 0.9111145214162045 1.0107619950669562 0.933010055437714 0.9458118144333985 0.9347221485046184 1.0 16.321706391085343 -6.263406303982693 24.999969478378443 0.9547922718714066 1.0929101285919198 0.7764399275902649 0.03735168594883401 80.81847114927898 1027215.6558269559 0.010973277269440489 0.013089225112697726 5.452475163642032e-07 6.263406303982693 0.13811785672051324 NVHS(ph)EDFENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NVHSEDFENR 10 0 Q9H2P0;A0A669KBJ7 Q9H2P0 ADNP Activity-dependent neuroprotector homeobox protein 1 NVHS(1)EDFENR;NVHS(1)EDFENR 116.03 0.00060921 16483900.0 87315.0 76087.0 80092.0 80748.0 92672.0 85538.0 87676.0 82173.0 70896.0 55164.0 True False 102095.70495014072 83640.41451853477 82001.69703060134 76223.9513485481 74513.58685151814 81052.23669895712 79370.69456072939 80016.04581949054 71932.7198779453 65164.79652201628 1.566730971309749 1.2835214561020905 1.2583741745114883 1.1697105709951143 1.1434638152571122 1.2438040326201767 1.2179995764110698 1.2279029489865234 1.1038585818900308 1.0 15.991805178376758 -1.522878919063937 0.8640769938024696 1.1708915246289886 155.1302737851231 0.754029077836279 0.06954249264432022 349.76429639067334 0.9118724250930423 0.022728477635742952 105955.78754205993 0.029999987995456643 1.522878919063937 153.95938226049412 NVHS(ph)EDFENR ddPTM_PC-9_Lapatinib_30min_R1 1 NVHSEDFENR 10 0 Q9H2P0;A0A669KBJ7 Q9H2P0 ADNP Activity-dependent neuroprotector homeobox protein 1 NVHS(1)EDFENR 94.54700000000001 0.0035479999999999995 7049800.0 37285.0 27968.0 32269.0 31070.0 34374.0 30926.0 27185.0 26322.0 34889.0 23713.0 True False 36753.30906276842 27903.241814348814 29615.967381942195 33354.99144648165 32352.188901884183 29603.367072027107 28592.50628277341 27545.016213185303 30959.43342254253 27811.760454413637 1.3215024314268387 1.0032893048998148 1.064872086414157 1.1993124815365046 1.1632557009439506 1.064419029516312 1.0280725065800669 0.9904089407908732 1.113177767847104 1.0 14.763407448163115 -6.907738499957134 4.400182990823273 1.0336518483849415 1.1398946852260634 0.3048805744351559 0.08415006635041873 0.308159689806379 10.78299700378156 0.03054536470892995 0.026704371001544012 1.236691853748016e-07 6.907738499957134 0.1062428368411219 NVIFQPVAELK ddPTM_PC-9_Lapatinib_30min_R1 2 NVIFQPVAELK 11 0 Q01813;B1APP6;Q01813-2;H0Y757 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 0 ; 140.3 0.00055195 4246600.0 51465.0 50759.0 49808.0 44204.0 44432.0 39877.0 52791.0 45368.0 45913.0 43570.0 False True 50731.09966247488 50641.47065412363 45712.97850444003 47454.90962022126 41818.59711667302 38171.553667827204 55524.25967165316 47475.96290402675 40741.79445467616 51101.01644662427 0.9927610679811864 0.9910071105340802 0.8945610417003715 0.9286490351867771 0.8183515715456098 0.7469822778906546 1.0865588110101299 0.9290610286317114 0.7972795315574893 1.0 15.641064367540523 -5.260029233773821 20.95923462205408 0.8969261584348824 0.9918841567061618 0.13292415160288318 0.09339029208427564 25.648378394028327 381087.7676724108 0.02468208506947042 0.05830878329411953 5.495038837193787e-06 5.260029233773821 0.09495799827127938 NVIGLQMGTNR ddPTM_PC-9_Lapatinib_30min_R1 1 NVIGLQMGTNR 11 0 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 0 105.4 0.011811 5934200.0 29904.0 29868.0 25279.0 23717.0 23501.0 24853.0 30373.0 22848.0 24788.0 18529.0 False True 29477.56347627804 29798.84248108444 23200.65819976189 25461.227297592683 22118.717384743697 23790.095125172644 31945.565323769613 23909.60149072478 21996.114410788046 21731.712961659443 1.3564307391821504 1.3712146177182432 1.0675945444656874 1.1716162155515812 1.0178082797139385 1.0947178976247633 1.4699975735980932 1.1002170667773734 1.0121666179557534 1.0 14.407514276290996 -5.252856395822494 24.60301094269011 1.1305968432033977 1.363822724134413 0.3653777971364772 0.12921562132510783 591.3507850440024 1695087.0861136967 0.034197914327221954 0.0873954687278636 5.586548894936317e-06 5.252856395822494 0.23322588093101526 NVIPDT(ph)PPSTPLVPSR ddPTM_PC-9_AZD4547_30min_R2 3 NVIPDTPPSTPLVPSR 16 0 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 NVIPDT(0.764)PPS(0.116)T(0.116)PLVPS(0.005)R;NVIPDT(0.96)PPS(0.023)T(0.008)PLVPS(0.008)R;NVIPDT(0.622)PPS(0.282)T(0.09)PLVPS(0.005)R 135.69 2.0439000000000002e-05 48961000.0 121406.0 117312.0 146084.0 210130.0 188610.0 151800.0 136287.0 180461.0 140526.0 155696.0 True False 160010.58259832565 155230.80983880573 144146.83071041008 161687.7749761374 162424.7571455823 142307.9220030041 148416.27897709748 152574.89903123712 147953.917470485 150245.13043017383 1.0649967965031006 1.033183633934472 0.9594109991964237 1.0761598363501141 1.0810650347238304 0.9471716094595256 0.9878275492334422 1.0155064499887139 0.9847501682541807 1.0 17.196958707183015 -6.7618069418706686 24.999999778072095 0.9880688374582527 1.039622405924576 0.3781734223317579 0.03570784513719549 12.676609454909276 862209.1554969982 0.012937208261789571 0.012127973918218368 1.730585490213332e-07 6.7618069418706686 0.05155356846632331 NVIPDT(ph)PPSTPLVPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NVIPDTPPSTPLVPSR 16 0 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 NVIPDT(0.958)PPS(0.034)T(0.007)PLVPS(0.001)R 84.035 0.012397 10733000.0 20561.0 21810.0 20011.0 22900.0 34136.0 32395.0 26660.0 31115.0 24694.0 24595.0 True False 24041.571201739054 23975.152662731423 20488.13813214011 21616.987242801715 27447.295847326357 30696.149171861773 24134.571798314773 30298.26421906761 25055.1030335418 29053.878806087116 0.8274823255854593 0.8251962783608899 0.7051773798907571 0.7440310254984857 0.9447033227651462 1.056524995396848 0.8306832956589021 1.0428302679062522 0.8623668874220152 1.0 14.826443161449488 -6.280684799100229 10.76996671721276 0.9571229793870282 0.773999620805737 0.5862736230470655 0.07436428434054779 0.44234206480983274 245.02016918788755 0.022246526654805015 0.02564831905243753 5.239805916210305e-07 6.280684799100229 -0.18312335858129114 NVIPDT(ph)PPSTPLVPSR ddPTM_PC-9_Lapatinib_30min_R1 3 NVIPDTPPSTPLVPSR 16 0 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 NVIPDT(0.983)PPS(0.011)T(0.006)PLVPSR;NVIPDT(0.897)PPS(0.074)T(0.027)PLVPS(0.002)R;NVIPDT(0.61)PPS(0.266)T(0.044)PLVPS(0.079)R 112.01 0.0009647999999999999 32200400.0 59006.0 66719.0 61487.0 60440.0 72818.0 79072.0 77910.0 74279.0 81690.0 67997.0 True False 58164.563619624845 66564.51625470298 56431.776206683804 64884.959221929515 68534.98840569626 75690.27488583472 81943.79858344233 77730.27350882131 72489.21196616412 79750.1908496927 0.7293344755656966 0.8346627831920663 0.7076067857071623 0.8136025573182629 0.8593708388092257 0.949092084663348 1.0275059872632026 0.9746719434856477 0.9089534607232032 1.0 16.283200350935743 -6.529322104595817 1.7830342089117737 0.9776302905439107 0.7667408599493666 0.8300188855598911 0.04324889167125549 0.13828720333522634 0.890006126821023 0.016451025293934506 0.017849975817638832 2.9558194012288717e-07 6.529322104595817 -0.21088943059454412 NVLGHMQQGGS(ph)PT(ph)PFDRNFATK ddPTM_PC-9_AZD4547_30min_R2 1 NVLGHMQQGGSPTPFDRNFATK 22 1 F8VZI0;A0A2R8Y891;P08237-2;P08237;P08237-3 F8VZI0 PFKM ATP-dependent 6-phosphofructokinase, muscle type 2 NVLGHMQQGGS(1)PT(1)PFDRNFAT(0.001)K 55.881 0.010159 71222000.0 18645.0 16021.0 25743.0 28312.0 24660.0 19956.0 22984.0 27672.0 19987.0 18925.0 True False 24573.722159907942 21199.474942269415 25401.630999822613 21785.105816039617 21236.384662584533 18708.148165296097 25029.53147409219 23395.928239300465 21043.47201573078 18262.441510321678 1.3455880007073104 1.1608237009431497 1.39092196327999 1.1928912026207985 1.1628447735524312 1.024405644487486 1.3705468384359147 1.2810953139029857 1.1522814188802357 1.0 14.156592032022221 -14.196129919371783 0.22501229784868126 1.6762871546202414e-12 1.2575336150784333 0.3057794495657773 0.10822720117626516 182.82276745078363 2.089429451214759 83.19829480135388 0.203415942140685 6.366050517584227e-15 14.196129919371783 1.257533615076757 NVMSAFGLTDDQVSGPPS(ph)APAEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NVMSAFGLTDDQVSGPPSAPAEDR 24 0 Q92734-4;Q92734-3;Q92734-2;Q92734 Q92734-4 TFG Protein TFG 1 NVMSAFGLTDDQVSGPPS(1)APAEDR;NVMSAFGLTDDQVS(0.002)GPPS(0.998)APAEDR 91.59200000000001 0.00028257 4634100.0 15080.3 18216.4 17899.9 19614.0 20977.8 18099.1 21635.7 11969.8 19686.6 13619.8 True False 17633.096940498286 20024.803804006453 18326.70150174877 18515.091169445983 16867.350680397318 17149.951334355414 19586.209867096728 11655.605433051434 19974.479281611882 16088.961925722528 1.0959748069455646 1.2446299454529397 1.1390853919822268 1.150794641377368 1.0483802968935072 1.065945174929938 1.2173693963302201 0.7244473252445714 1.2415020542548063 1.0 13.973783624633482 -6.559737009030912 0.7607514213844709 1.016193136282218 1.1769547177347608 0.12272511617300319 0.13675682442788656 1.2740165283691967 1.6411531986067667 0.08427689207268145 0.10303578598017561 2.755897056643947e-07 6.559737009030912 0.1607615814525427 NVPESSPHS(ph)PCEGLPSEAALTPRPEGK ddPTM_PC-9_AZD4547_30min_R2 1 NVPESSPHSPCEGLPSEAALTPRPEGK 27 1 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2;H0YCW2;S4R3B3;H7C453;S4R3U7 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 NVPES(0.097)S(0.097)PHS(0.802)PCEGLPS(0.003)EAALTPRPEGK 42.472 0.025881 6669500.0 14369.0 10166.0 20106.0 43489.0 29422.0 27119.0 20718.0 31734.0 22542.0 28549.0 True False 18938.043106233148 13451.960693034809 19839.381302972968 33463.28294835216 25337.263160687842 25423.24464294773 22561.861863915838 26830.239474774546 23733.524099594903 27549.508199639284 0.6874185545889749 0.48828315175553444 0.720135588599463 1.2146599026689813 0.9196992910755334 0.9228202717346732 0.8189569737659146 0.9738917762287257 0.8614863077630422 1.0 14.749738944288733 -5.533058230478621 24.946372225615466 0.9501811011972968 0.5919404497815052 0.6631100324203922 0.10937017549956142 108.84007145462031 266728.23336764384 0.029354619918959407 0.050914278969020704 2.9305002955756445e-06 5.533058230478621 -0.35824065141579164 NVPESSPHS(ph)PCEGLPSEAALTPRPEGK ddPTM_PC-9_Lapatinib_30min_R1 2 NVPESSPHSPCEGLPSEAALTPRPEGK 27 1 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2;H0YCW2;S4R3B3;H7C453;S4R3U7 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 NVPES(0.091)S(0.244)PHS(0.665)PCEGLPSEAALTPRPEGK;NVPES(0.241)S(0.146)PHS(0.613)PCEGLPSEAALTPRPEGK 72.654 4.7808999999999996e-05 14191200.0 62716.0 60260.0 72364.0 58485.0 75155.0 74396.0 63607.0 63262.0 74206.0 60228.0 True False 61821.658339294176 60120.471672363376 66414.51125311785 62786.182000240704 70734.53066041495 71214.25650554648 66900.25922855867 66201.38346928543 65848.13885617795 70638.32955123464 0.8751857346011326 0.8511026811408025 0.9402050087402871 0.8888401297018399 1.0013618825613726 1.008153179130519 0.9470815583207597 0.9371878396596135 0.9321870898492536 1.0 16.10816360621866 -5.659803357830081 1.3545894821134006 0.9658723715388342 0.8629037249263015 0.5642769075171707 0.034181921120900294 0.3716806472192295 1.3242103803410308 0.0118738180067357 0.03351443187024763 2.1887524346118027e-06 5.659803357830081 -0.10296864661253269 NVPHEDICEDS(ph)DIDGDYR ddPTM_PC-9_AZD4547_30min_R2 2 NVPHEDICEDSDIDGDYR 18 0 O00629 O00629 KPNA4 Importin subunit alpha-3 1 NVPHEDICEDS(1)DIDGDYR;NVPHEDICEDS(1)DIDGDYR 207.37 1.5459999999999997e-67 32148000.0 75353.0 93846.0 103195.0 118948.0 106341.0 107636.0 103154.0 131600.0 106112.0 110901.0 True False 99313.68656023276 124179.8842414466 101826.56687358486 91526.37632828049 91577.38772927405 100905.5039045805 112334.506164223 111264.24386715611 111720.86368805864 107018.38974563731 0.9280058015849688 1.1603602384281706 0.9514866287523813 0.8552397073607775 0.8557163675040932 0.9428800428077269 1.0496747935679196 1.0396740609871855 1.0439408026377357 1.0 16.707499201111965 -7.259026697151753 23.972056803244616 1.0366285891702023 0.9501758737225424 0.20959187674800517 0.08014611824379306 220.87316262765836 2194586.3502896633 0.035340902629427594 0.026048388236326936 5.507738379399996e-08 7.259026697151753 -0.08645271544765987 NVPHEDICEDS(ph)DIDGDYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NVPHEDICEDSDIDGDYR 18 0 O00629 O00629 KPNA4 Importin subunit alpha-3 1 NVPHEDICEDS(1)DIDGDYR 170.02 3.7012e-25 0.0 28814.0 30326.0 32205.0 31125.0 36767.0 24543.0 31335.0 31338.0 25371.0 20110.0 True False 33691.64109755892 33336.564862448125 32972.88933814262 29381.167158611508 29562.7702841179 23255.921874517786 28366.72195424581 30515.410705355625 25742.002877783612 23755.78380932758 1.4182500298866199 1.403303091576322 1.3879941660858184 1.2368005785216463 1.2444451642344987 0.9789583059510112 1.194097495663678 1.284546574016805 1.0836099151431138 1.0 14.535991188031511 -1.522878745280376 0.19972424606355474 1.0284526101651368 3.1435271429422484 0.6582760380071783 0.08900917741270266 35.415386681714445 0.4275177996516162 0.17662923565869224 23.429680375442306 0.02999999999999734 1.522878745280376 2.1150745327771117 NVPHEDICEDS(ph)DIDGDYR ddPTM_PC-9_Lapatinib_30min_R1 4 NVPHEDICEDSDIDGDYR 18 0 O00629 O00629 KPNA4 Importin subunit alpha-3 1 NVPHEDICEDS(1)DIDGDYR;NVPHEDICEDS(1)DIDGDYR;NVPHEDICEDS(1)DIDGDYR;NVPHEDICEDS(1)DIDGDYR 171.83 2.8112e-08 78602300.0 93823.0 152165.0 165130.0 159376.0 185958.0 159425.0 161535.0 155652.0 169454.0 144008.0 True False 92485.06681496925 151812.67129148985 151553.64882023368 171097.0427027502 175020.31604749453 152606.76438782652 169898.49190317452 162884.16015556303 150368.3060902726 168899.59092140172 0.5475742499459791 0.8988338601846386 0.8973002716789287 1.0130104032186262 1.036238839257705 0.903535429276693 1.0059141705218082 0.964384574687111 0.8902822397020919 1.0 17.365806308340588 -4.452309260448215 1.6178165813475451 0.96865627371798 8.738660603417028e-13 0.864167096090984 0.04924699923509735 0.885796415885932 1.1260816425699653 0.013597704563676169 1.7488444762921107 3.5293175811282385e-05 4.452309260448215 -0.9686562737171062 NVPHEDICEDSDIDGDYR ddPTM_PC-9_AZD4547_30min_R2 2 NVPHEDICEDSDIDGDYR 18 0 O00629 O00629 KPNA4 Importin subunit alpha-3 0 ; 216.77 1.2743000000000001e-27 13498200.0 61242.0 53204.0 67386.0 91111.0 73123.0 84194.0 69890.0 87248.0 68538.0 66039.0 False True 80715.6820872663 70401.15253907381 66492.41761076974 70106.7666009177 62971.133644856796 78929.33587036189 76110.07460512992 73765.82635958676 72160.77875689973 63726.99471070725 1.2665854157046048 1.1047304656160912 1.0433948425249975 1.1001109799571098 0.9881390756102381 1.2385541830219144 1.1943145122508358 1.1575287159617589 1.1323424097508157 1.0 15.95961700612108 -6.7793699112057375 24.999876735354952 1.1575038694397726 1.097617643922405 0.04881904941930537 0.08769114320501832 615.6692811716057 858399.0799071076 0.03072546737523195 0.027151861837270936 1.6619964384880028e-07 6.7793699112057375 -0.05988622551736755 NVPHEDICEDSDIDGDYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NVPHEDICEDSDIDGDYR 18 0 O00629 O00629 KPNA4 Importin subunit alpha-3 0 ; 177.66 1.3664e-08 7504500.0 46812.0 47501.0 53508.0 48151.0 62076.0 52294.0 51401.0 43422.0 46718.0 38673.0 False True 54736.347020855435 52216.5853568274 54783.83365022 45453.25557764823 49912.653416294546 49551.610581674315 46531.925168986374 42282.21850941199 47401.16236822729 45684.10876470047 1.1981485138033277 1.1429923176519206 1.1991879699872963 0.9949467507784542 1.0925605153725013 1.0846574864116034 1.0185582345198556 0.9255344944385328 1.0375853584529937 1.0 15.47940479005505 -5.653915299414368 0.4660789548172248 0.9834281269304166 1.2552281358326682 0.6365129813899126 0.05195438958597198 1.4846708347715254 0.4456264816953786 0.041786148522062236 0.20566517705510678 2.2186290775157047e-06 5.653915299414368 0.27180000890225164 NVPHEDICEDSDIDGDYR ddPTM_PC-9_Lapatinib_30min_R1 2 NVPHEDICEDSDIDGDYR 18 0 O00629 O00629 KPNA4 Importin subunit alpha-3 0 ; 170.0 6.3927e-08 9568200.0 28859.0 41642.0 59186.0 52485.0 61291.0 49861.0 44724.0 43674.0 61427.0 42034.0 False True 28447.465367907545 41545.58050747685 54319.955544566896 56344.921984827415 57685.983882742265 47728.56126166795 47039.589883787325 45703.25347977569 54508.44440501363 49299.520893215675 0.5770333028088783 0.8427177334535542 1.10183536392221 1.1429101330796358 1.1701124643318934 0.9681343833959264 0.9541591689232958 0.9270526904058639 1.1056587045354993 1.0 15.589286005699483 -4.9170942765205305 2.712411868007444 1.0446013296150287 0.5500627514333504 0.769548866468584 0.08011946232673749 0.17707880099065262 2.165748401616534 0.023604244257644628 0.17375393387132168 1.2103353657795724e-05 4.9170942765205305 -0.49453857818167835 NVPNLHVMK ddPTM_PC-9_Lapatinib_30min_R1 2 NVPNLHVMK 9 0 P46783;F6U211;A0A2R8Y7H1;S4R435;A0A2R8YFH6;A0A1W2PQS6;A0A2R8Y6L3;Q9NQ39 P46783 RPS10;RPS10-NUDT3;RPS10P5 40S ribosomal protein S10;Putative 40S ribosomal protein S10-like 0 ; 83.948 0.011403 5750500.0 66906.0 82807.0 82987.0 82690.0 76032.0 77619.0 79125.0 79173.0 69745.0 76306.0 False True 65951.90817094214 82615.26547914672 76164.12919908394 88771.29844575378 71559.9472446634 74299.41630872636 83221.7053384016 82851.66661524662 61889.58365259057 89495.39042864618 0.7369307833069344 0.9231231361017983 0.8510396885726631 0.9919091700765337 0.799593665125328 0.830203834553519 0.9298993494503326 0.9257646256239697 0.6915393447211624 1.0 16.44952575603815 -11.726161246471952 2.431148251894671 1.432213337610677 0.8615160089591746 0.19199419350535152 0.0888482476989755 20218848.3732558 4319478.281017547 48081475.95782868 0.02101011571970045 1.8786191865769434e-12 11.726161246471952 -0.5706973286515024 NVPNWHR ddPTM_PC-9_AZD4547_30min_R2 2 NVPNWHR 7 0 F5H018;B5MDF5;J3KQE5;P62826;B4DV51 F5H018 RAN GTP-binding nuclear protein Ran 0 ; 121.29 0.004770600000000001 27185000.0 93909.0 86415.0 105687.0 129204.0 120423.0 115209.0 117212.0 136347.0 108072.0 111199.0 False True 123770.10857145573 114346.9588125716 104285.52132534084 99418.01398190089 103704.34510228776 108004.96301741833 127643.64093026872 115277.70409236409 113784.46528663924 107305.95685634132 1.1534318522237887 1.065616133181279 0.9718521168862586 0.9264910997904746 0.9664360501544633 1.006514141260702 1.1895298701930874 1.0742898853853486 1.0603741732527598 1.0 16.711370640825393 NVPNWHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NVPNWHR 7 0 F5H018;B5MDF5;J3KQE5;P62826;B4DV51 F5H018 RAN GTP-binding nuclear protein Ran 0 ;; 103.29 0.004206199999999999 14361000.0 73022.0 79091.0 84899.0 104929.0 135762.0 86492.0 98078.0 91214.0 86295.0 69319.0 False True 85383.18234975851 86942.63178579071 86923.31414125038 99050.16831440773 109160.41067567126 81956.20725953594 88787.34181677108 88819.72914922182 87556.9011208992 81885.98597109801 1.042708118332908 1.0617522736610567 1.061516364618609 1.2096107427877572 1.3330780521370271 1.0008575495257848 1.0842800604258331 1.0846755778280681 1.0692537933389819 1.0 16.321328948632335 NVPNWHR ddPTM_PC-9_Lapatinib_30min_R1 2 NVPNWHR 7 0 F5H018;B5MDF5;J3KQE5;P62826;B4DV51 F5H018 RAN GTP-binding nuclear protein Ran 0 ; 114.19 0.0073624 22910100.0 94120.0 89119.0 91891.0 101967.0 111174.0 95296.0 82194.0 88891.0 98267.0 92708.0 False True 92777.83154050603 88912.65043095498 84336.07668951787 109465.99333194079 104634.96389649367 91220.41222582603 86449.60314166933 93021.20037254985 87199.13566261546 108732.45427435484 0.8532671515572348 0.817719521042077 0.775629293501646 1.0067462751805 0.9623158475985253 0.8389437434720066 0.7950671556032278 0.8555053869917975 0.8019605208449881 1.0 16.730423092192595 NVPQEES(ph)LEDSDVDADFK ddPTM_PC-9_AZD4547_30min_R2 1 NVPQEESLEDSDVDADFK 18 0 O00505 O00505 KPNA3 Importin subunit alpha-4 1 NVPQEES(0.8)LEDS(0.2)DVDADFK 132.06 8.930800000000001e-06 0.0 6913.5 11067.0 8626.5 8195.4 7984.2 8875.7 7103.4 6791.7 7930.3 8192.2 True False 9111.849190266743 14644.191323019513 8512.106973545033 6306.077147667809 6875.731647323903 8320.70107590292 7735.588838890807 5742.198822739851 8349.47946797167 7905.393571511617 1.1526117084293928 1.8524303933193484 1.076746767449986 0.7976930042285046 0.8697519718817961 1.0525347031282455 0.9785203948311025 0.7263646990875706 1.0561750521897342 1.0 12.948621573878713 -5.459922882330521 6.901028675261684 0.920588021311985 1.4991693451373374 0.5991333272556176 0.18602759795683071 0.146326122673996 13.474567778189286 0.04538230555800571 0.09449186867514234 3.4679842598055227e-06 5.459922882330521 0.5785813238253523 NVPQEES(ph)LEDSDVDADFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NVPQEESLEDSDVDADFK 18 0 O00505 O00505 KPNA3 Importin subunit alpha-4 1 NVPQEES(0.612)LEDS(0.388)DVDADFK;NVPQEES(0.775)LEDS(0.225)DVDADFK 104.88 0.00035548 6891000.0 31646.0 34629.0 30343.0 37457.0 38654.0 31002.0 35892.0 32670.0 28573.7 28738.0 True False 37003.04276300927 38066.73826491183 31066.49219646831 35358.405727232486 31080.026180060748 29376.20054409814 32492.049924422852 31812.447116726282 28991.536306370508 33947.971910117165 1.089992735382865 1.1213258443155243 0.9151207111494599 1.0415469242418862 0.9155193795479218 0.865330059241137 0.957113138023411 0.9370941863907206 0.8539990660747089 1.0 15.051037768375467 -5.237038358724989 0.9838401355022365 0.9211457420086503 1.1524454385928602 0.5432044602081546 0.05851482157269971 0.7789455757278715 0.9725673840006888 0.0201562038404942 0.1636385281971847 5.793775210944313e-06 5.237038358724989 0.2312996965842099 NVPQEESLEDS(ph)DVDADFK ddPTM_PC-9_AZD4547_30min_R2 3 NVPQEESLEDSDVDADFK 18 0 O00505 O00505 KPNA3 Importin subunit alpha-4 1 NVPQEESLEDS(1)DVDADFK;NVPQEESLEDS(1)DVDADFK;NVPQEESLEDS(1)DVDADFK 143.46 6.0354e-05 14888800.0 52162.5 52226.2 54435.0 60411.8 60215.0 64689.0 60371.2 64071.5 61041.0 57970.0 True False 68749.08995259844 69107.29781099503 53713.15633280284 46484.792863005845 51855.18663655831 60643.9866037703 65744.11984548875 54170.721891599474 64267.5026423287 55940.48794469473 1.2289683640329858 1.23537173789613 0.9601839080471746 0.8309686699365725 0.926970581447639 1.0840804010098315 1.1752510973891812 0.9683634140831069 1.1488548813851325 1.0 15.77160521742364 -5.253969829686888 24.521381508664252 1.0096304642078684 1.2321700960077029 0.44875245747774817 0.09765772050558581 429.1470048038611 1408811.1073364902 0.027515315895204437 0.06979442326724619 5.57224457810652e-06 5.253969829686888 0.2225396317998345 NVPQEESLEDS(ph)DVDADFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NVPQEESLEDSDVDADFK 18 0 O00505 O00505 KPNA3 Importin subunit alpha-4 1 NVPQEES(0.117)LEDS(0.883)DVDADFK;NVPQEES(0.288)LEDS(0.712)DVDADFK;NVPQEES(0.002)LEDS(0.998)DVDADFK 141.07 2.1726000000000002e-08 8884600.0 23096.2 25924.6 19603.899999999998 24826.4 27077.2 24264.399999999998 25788.9 23790.68 24094.7 19130.5 True False 27005.930489256614 28498.22295828736 20071.331324204755 23435.45729627479 21771.61703530657 22991.932148965065 23345.988696532615 23166.199858309083 24447.039404805997 22598.70821304533 1.1950209823793012 1.2610553970441758 0.8881627717383588 1.0370264121002473 0.9634009532783244 1.0174002837778462 1.03306739820889 1.025111685142081 1.0817892409750085 1.0 14.463952687238697 -5.247037550486826 24.99854515179449 1.0076386764538587 1.2280382228161373 0.7533275607803384 0.05087166778683274 367.3684187810061 637671.72793183 0.01262606570309151 0.03307056353385911 5.661903322988491e-06 5.247037550486826 0.22039954636227854 NVPQEESLEDS(ph)DVDADFK ddPTM_PC-9_Lapatinib_30min_R1 5 NVPQEESLEDSDVDADFK 18 0 O00505 O00505 KPNA3 Importin subunit alpha-4 1 NVPQEES(0.001)LEDS(0.999)DVDADFK;NVPQEESLEDS(1)DVDADFK;NVPQEESLEDS(1)DVDADFK;NVPQEESLEDS(1)DVDADFK;NVPQEESLEDS(1)DVDADFK 186.01 2.0615999999999998e-42 26850500.0 74114.6 97316.2 94553.6 86346.4 100499.3 95044.0 86914.7 92229.2 93434.4 83399.6 True False 73057.71221304686 97090.87031798971 86779.76799545101 92696.60229914649 94588.12876322608 90979.18967838542 91414.71788910666 96514.50533124781 82910.8339641494 97815.10973701821 0.7468959796647666 0.992595832883328 0.8871816248917332 0.9476716076725453 0.9670093814496752 0.9301138640337717 0.93456642981724 0.9867034407131255 0.8476280830953433 1.0 16.57776971854011 -4.752140807739449 24.999793336189846 0.9416767859046932 0.7468955993602385 0.6272298124495587 0.04549568836151496 226.2197120640407 608162.6001937104 0.010380836674498978 0.12722528703715885 1.7695351434281875e-05 4.752140807739449 -0.19478118654445464 NVS(ph)PEFVPCEGEGGFGLHK ddPTM_PC-9_AZD4547_30min_R2 4 NVSPEFVPCEGEGGFGLHK 19 0 O94986-3;O94986 O94986-3 CEP152 Centrosomal protein of 152 kDa 1 NVS(1)PEFVPCEGEGGFGLHK;NVS(1)PEFVPCEGEGGFGLHK;NVS(1)PEFVPCEGEGGFGLHK;NVS(1)PEFVPCEGEGGFGLHK 134.62 2.504e-05 34581200.0 123742.0 116564.0 156217.0 201554.0 189936.0 158431.0 155018.0 188911.0 135228.0 159390.0 True False 163089.38200650705 154241.03346674299 154145.46050962532 155088.8392782582 163566.66493400844 148524.28452475613 168814.3016903422 159719.14569292037 142375.87600656642 153809.8046145399 1.060331507573412 1.0028036499577109 1.002182278925109 1.0083156900623056 1.0634345797650548 0.9656360002339921 1.0975522796703683 1.0384197944545197 0.9256619001849209 1.0 17.23078794534335 -8.245830601672331 24.591198769339307 0.9628309470255431 1.028531729952969 0.3152225752933858 0.039465063162423576 670.6927661478288 1056663.0549078768 0.025981699641100163 0.009741905983093227 5.677660216677753e-09 8.245830601672331 0.06570078292742598 NVS(ph)PEFVPCEGEGGFGLHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NVSPEFVPCEGEGGFGLHK 19 0 O94986-3;O94986 O94986-3 CEP152 Centrosomal protein of 152 kDa 1 NVS(1)PEFVPCEGEGGFGLHK;NVS(1)PEFVPCEGEGGFGLHK 124.66 1.5557e-05 22285000.0 112763.0 99672.0 111056.0 137215.0 166130.0 126529.0 136281.0 129304.0 122000.0 97963.0 True False 131851.5487292298 109566.77745070014 113703.99622222563 129527.28840703204 133578.01907418334 119893.59649842567 123371.47709100279 125909.90700891239 123784.01919867593 115722.91642531857 1.1393728468148294 0.9468027667744506 0.9825538427006733 1.1192881445450096 1.1542918481525437 1.0360402261016177 1.0660937427257131 1.0880291553157317 1.0696586555400163 1.0 16.82031506178106 -5.758516849649122 24.997295513116004 1.0810275117598924 1.0152991152457038 0.1320626964543581 0.060811551174621004 125.51391029229458 1073529.4565571663 0.016557620961742247 0.02712694897100281 1.7437457027420302e-06 5.758516849649122 -0.0657283965141886 NVS(ph)PEFVPCEGEGGFGLHK ddPTM_PC-9_Lapatinib_30min_R1 2 NVSPEFVPCEGEGGFGLHK 19 0 O94986-3;O94986 O94986-3 CEP152 Centrosomal protein of 152 kDa 1 NVS(1)PEFVPCEGEGGFGLHK;NVS(1)PEFVPCEGEGGFGLHK 126.93 1.8003e-05 17789700.0 73746.0 75119.0 84924.0 70469.0 81347.0 89720.0 70380.0 79516.0 77114.0 77621.0 True False 72694.36851664002 74945.06657079776 77941.87653611992 75651.52533769263 76562.32939435533 85882.88474753516 74023.9320280153 83210.60364742963 68428.60927358031 91037.686426519 0.7985085228996371 0.8232312299729807 0.8561495749239042 0.8309912993972524 0.8409959918758761 0.9433772772428205 0.8131130626629409 0.9140237072543909 0.7516514529267219 1.0 16.474176273931647 -11.910961285138683 2.391951948259179 2.312196918217494 0.8452355450593173 0.4532866016032956 0.05211625683488081 4009425.898065467 956519.8819896234 28107964.5832247 0.012395275446983706 1.2275486552006796e-12 11.910961285138683 -1.4669613731581768 NVS(ph)SFPDDATSPLQENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NVSSFPDDATSPLQENR 17 0 P52292;J3QLL0;J3KS65 P52292 KPNA2 Importin subunit alpha-1 1 NVS(0.496)S(0.496)FPDDAT(0.008)SPLQENR 179.09 2.9008999999999996e-06 7125600.0 17560.0 17236.0 25948.0 31567.0 34774.0 34696.0 37876.0 36152.0 29528.0 21556.0 True False 20532.561174190818 18947.07617124435 26566.698728337997 29798.40333159482 27960.2843272477 32876.48068118277 34288.11108150674 35203.04830621027 29959.79113851229 25463.93216279789 0.8063389834264612 0.7440750332710009 1.0433070021742838 1.1702200249782897 1.0980348262196877 1.2910999161871164 1.3465363818240426 1.3824670942864419 1.1765579230643226 1.0 14.636167598228544 -5.503968710249914 1.1668242896142131 1.2530510931981262 0.7179919065159888 0.6943795321626101 0.11243966415443292 0.32763487205657155 0.7685348544606647 0.03823116145182919 0.15785743337832267 3.1335114772624457e-06 5.503968710249914 -0.5350591866821375 NVSEELDRT(ph)PPEVSK ddPTM_PC-9_AZD4547_30min_R2 1 NVSEELDRTPPEVSK 15 1 Q15393;Q15393-3 Q15393 SF3B3 Splicing factor 3B subunit 3 1 NVS(0.002)EELDRT(0.998)PPEVSK 73.44800000000001 0.012673 21583000.0 22663.0 19024.0 27852.0 36320.0 28564.0 30420.0 24815.0 31651.0 24665.0 27309.0 True False 29869.36258031611 25173.13596540374 27482.664281826477 27946.985138406282 24598.381650529802 28517.832591115828 27023.48692697519 26760.06521762429 25968.741545404515 26352.920222212673 1.1334365348679443 0.9552313653720053 1.0428697863495808 1.0604891185778336 0.9334214744746206 1.082150757891278 1.0254456317974696 1.015449710771273 0.9854217796901181 1.0 14.685675218325441 -4.7424736292729905 24.989346454082575 1.0144145463682626 1.1334369294818498 0.4160190142014649 0.04330636107195051 1291.8387748442235 1702042.9914742531 0.01035346108822426 0.36491353988184194 1.809365773133169e-05 4.7424736292729905 0.11902238311358726 NVSGIS(ph)FTENMGSSQQK ddPTM_PC-9_AZD4547_30min_R2 2 NVSGISFTENMGSSQQK 17 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 NVS(0.005)GIS(0.963)FT(0.027)ENMGS(0.005)SQQK;NVS(0.022)GIS(0.634)FT(0.342)ENMGS(0.001)S(0.001)QQK 107.69 0.00050509 10958800.0 38160.0 35911.0 51591.0 70907.0 58114.0 51624.0 60821.0 71990.0 56266.0 71707.0 True False 50294.08622269172 47518.52847212013 50906.86963103945 54560.486652229476 50045.874220658436 48395.94311912439 66233.9511741107 60865.599665627335 59240.10589068436 69196.55975591214 0.7268292874689425 0.686718077311064 0.7356849792910403 0.7884855380771707 0.7232422304980636 0.6993981101060368 0.9571856087607258 0.8796044179122213 0.8561134556349516 1.0 16.078412692751606 -7.258538991189995 24.99978649127783 0.9131929091089771 0.7279638820223243 0.8209572149046584 0.04485574019109859 111.1328457169817 957910.8557323297 0.017848927438565237 0.013207422346318828 5.51392695829379e-08 7.258538991189995 -0.1852290270866528 NVSGIS(ph)FTENMGSSQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NVSGISFTENMGSSQQK 17 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 NVSGIS(0.757)FT(0.243)ENMGSSQQK 137.45 1.053e-07 0.0 23451.0 21833.0 19573.0 28141.0 27409.0 20139.0 30072.0 36427.0 27515.0 19247.0 True False 27420.791121637176 24000.43595072972 20039.69455101586 26564.351004352953 22038.403207152813 19082.87538731669 27223.362457573938 35470.82984759685 27917.354821734116 22736.328740831843 1.2060342474021575 1.0555985631764588 0.8813953553999623 1.1683658917477922 0.9693035079834311 0.8393120808921992 1.1973508462113276 1.56009487072094 1.227874347699668 1.0 14.472711699083522 -7.515271797625709 24.955139807365647 1.3121353453120277 1.0196397856563992 0.29913190547080903 0.166832563934212 356.0907238753165 1168193.2675732127 0.07283805202837103 0.044366320574314395 3.0530098281970976e-08 7.515271797625709 -0.29249555965562846 NVSGIS(ph)FTENMGSSQQK ddPTM_PC-9_Lapatinib_30min_R1 1 NVSGISFTENMGSSQQK 17 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 NVS(0.002)GIS(0.991)FT(0.007)ENMGSSQQK 93.226 0.013497 0.0 18772.0 16182.0 18984.0 15665.0 14866.0 18060.0 15480.0 12494.0 13602.0 11591.0 True False 18504.30783763681 16144.531573219117 17423.208800359174 16817.05635690809 13991.611107680528 17287.615899916244 16281.478655778272 13074.516851589447 12069.999524590094 13594.488905963333 1.3611624508752032 1.1875791495285408 1.2816376489679095 1.2370495480364219 1.0292119993965345 1.2716635409759973 1.1976528701006381 0.9617512612669245 0.8878597502327205 1.0 13.73073429283249 -7.7617068444495345 4.61635090762654 0.9379572609115335 1.2211485889274736 0.6918041797396517 0.08392058315718996 0.10840611294496333 5.7868326619652946 0.045496176101478186 0.022887063839650664 1.730984406424144e-08 7.7617068444495345 0.28319132801594005 NVSGISFT(ph)ENMGSSQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NVSGISFTENMGSSQQK 17 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 NVS(0.001)GIS(0.33)FT(0.531)ENMGS(0.132)S(0.006)QQK 84.94 0.012681 4918400.0 24837.0 24389.0 27281.0 31455.0 33781.0 32860.0 35174.0 39666.0 32575.0 20257.0 True False 29041.4135468894 26810.178738714218 27931.482503768657 29692.67832848594 27161.855548937525 31136.76375327607 31842.06408229271 38624.809529601014 33051.34774915462 23929.43374567622 1.2136272782525352 1.1203850046622401 1.167243771859648 1.2408433331127644 1.135081416368466 1.3011909970039361 1.3306651724697085 1.6141129765170514 1.3812005791874047 1.0 14.546498637605533 -7.005086109933175 2.657830967032839 1.3820579464785085 1.1755268969742185 0.17664690154365315 0.14622160630500236 0.35595131990545364 5.0631360186729255 0.057713886341344764 0.046086671422085154 9.883571082790278e-08 7.005086109933175 -0.20653104950429002 NVSS(ph)FPDDATSPLQENR ddPTM_PC-9_AZD4547_30min_R2 2 NVSSFPDDATSPLQENR 17 0 P52292;J3QLL0;J3KS65 P52292 KPNA2 Importin subunit alpha-1 1 NVS(0.032)S(0.955)FPDDAT(0.012)S(0.001)PLQENR;NVS(0.043)S(0.957)FPDDATSPLQENR 187.75 2.231e-08 17254800.0 43650.0 40001.0 59416.0 91305.0 73051.0 65076.0 56073.0 70593.0 62949.0 58740.0 True False 57529.7920235978 52930.54098781092 58628.10501827527 70256.0428981879 62909.1296020464 61006.78743259213 61063.388372205496 59684.47391576102 66276.35562706956 56683.53047906447 1.0149295842616206 0.9337904774184861 1.034305811984118 1.2394436674006446 1.1098308286439795 1.0762700720471956 1.0772686149949442 1.052942069968717 1.1692347859586498 1.0 15.790641997473978 -5.526788102293762 24.999829357027394 1.1063473576267382 0.9767820372955447 0.40105220888595094 0.06395092028512185 98.2476706642339 628278.3632095149 0.0171166641346885 0.029816203381655183 2.9731162985124918e-06 5.526788102293762 -0.1295653203311935 NVSS(ph)FPDDATSPLQENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NVSSFPDDATSPLQENR 17 0 P52292;J3QLL0;J3KS65 P52292 KPNA2 Importin subunit alpha-1 1 NVS(0.049)S(0.692)FPDDAT(0.092)S(0.167)PLQENR;NVS(0.031)S(0.961)FPDDAT(0.008)SPLQENR;NVS(0.038)S(0.961)FPDDAT(0.001)SPLQENR 180.39 1.9886000000000003e-06 7733700.0 30296.8 32111.4 38847.0 42864.9 51350.0 48763.1 54498.0 51291.5 49225.0 34482.3 True False 35425.44985092397 35299.2075751506 39773.25980806789 40463.31862288085 41288.33611905932 46205.87719346853 49335.55490864808 49945.15247283647 49944.82250044928 40733.66802826338 0.8696847488996998 0.8665855368256539 0.9764222505194202 0.9933629987558461 1.0136169443520548 1.1343411833525086 1.211173883835264 1.2261393311837672 1.2261312304552259 1.0 15.313934113063755 -6.317960488828508 0.941993470890135 1.187869601496584 0.8785402987188117 0.7252799747348697 0.06908021084458178 0.27723833114208757 0.5267114784059662 0.03346057424208332 0.0499866127118486 4.808830961623916e-07 6.317960488828508 -0.30932930277777226 NVSS(ph)FPDDATSPLQENR ddPTM_PC-9_Lapatinib_30min_R1 1 NVSSFPDDATSPLQENR 17 0 P52292;J3QLL0;J3KS65 P52292 KPNA2 Importin subunit alpha-1 1 NVS(0.04)S(0.959)FPDDATSPLQENR 166.36 2.3963e-05 6406500.0 23884.0 22079.0 25216.0 22069.0 30842.0 30071.0 24818.0 25251.0 35511.0 25491.0 True False 23543.40978021083 22027.877432029713 23142.837816574844 23692.02788002586 29027.934197705 28784.933428924745 26102.954604593375 26424.253643307573 31511.37723259217 29897.08538537754 0.7874817721103259 0.7367901301443718 0.7740834104147774 0.7924527616867117 0.9709285645584156 0.9628006562473564 0.8730936232787478 0.8838404581147397 1.0539949572477112 1.0 14.867717225008969 -6.194828773554745 4.706326751477239 0.9477605478089973 0.7668740041899924 0.7574986832220327 0.05110194862139992 0.11497460983685873 5.040365192653545 0.015730660637718604 0.020353710545464365 6.385151797747738e-07 6.194828773554745 -0.1808865436190049 NVSSFPDDAT(ph)SPLQENR ddPTM_PC-9_AZD4547_30min_R2 3 NVSSFPDDATSPLQENR 17 0 P52292;J3QLL0;J3KS65 P52292 KPNA2 Importin subunit alpha-1 1 NVSSFPDDAT(0.5)S(0.5)PLQENR;NVSSFPDDAT(0.603)S(0.397)PLQENR;NVSSFPDDAT(0.897)S(0.103)PLQENR 183.73 3.1148000000000004e-33 24003000.0 30128.9 32375.2 42517.5 52029.4 45088.5 37983.7 29731.5 53700.6 34168.7 41640.5 True False 39709.26347994906 42839.85026845768 41953.690169559035 40034.82567621684 38828.74005916233 35608.573234423595 32377.545902452657 45402.40618702587 35974.787725216425 40182.6787693818 0.9882184238599477 1.0661272861952793 1.0440740004005582 0.9963204769394912 0.9663054143804087 0.8861672323736774 0.8057587720389499 1.1298999364278663 0.8952809724728537 1.0 15.294286123772023 -6.136075321115262 2.5047563712300493 0.9426067831468942 1.035049966213323 0.18458855035522947 0.08137490110248494 0.49460079398924084 6.0613575488209674 0.026382315416617435 0.03644312634066728 7.310122906314545e-07 6.136075321115262 0.09244318306642885 NVSSFPDDAT(ph)SPLQENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NVSSFPDDATSPLQENR 17 0 P52292;J3QLL0;J3KS65 P52292 KPNA2 Importin subunit alpha-1 1 NVSSFPDDAT(0.5)S(0.5)PLQENR 127.88 8.1735e-05 45608000.0 20918.0 17802.0 20667.0 21894.0 24612.0 17512.0 16264.0 21263.0 13161.0 12580.0 True False 24459.004250667636 19569.264910680664 21159.779660033957 20667.350161305716 19789.45527872031 16593.63989188589 14723.356178836873 20704.86878001076 13353.454726834188 14860.654416774796 1.6458901179384244 1.316850817053572 1.4238793976763682 1.3907429364602064 1.3316678205222143 1.116615690433854 0.9907609561404686 1.39326763137961 0.8985778386556603 1.0 13.85921002860545 -5.060326222081356 0.2594273005702972 0.9669906461621912 1.9564965829846666 0.6276097897338844 0.1377331068066761 5.713103565079924 0.36753096120652723 0.19432736626345554 1.7983831317721843 8.703096077346609e-06 5.060326222081356 0.9895059368224753 NVSSFPDDAT(ph)SPLQENR ddPTM_PC-9_Lapatinib_30min_R1 5 NVSSFPDDATSPLQENR 17 0 P52292;J3QLL0;J3KS65 P52292 KPNA2 Importin subunit alpha-1 1 NVSSFPDDAT(0.879)S(0.121)PLQENR;NVSSFPDDAT(0.5)S(0.5)PLQENR;NVSSFPDDAT(0.5)S(0.5)PLQENR;NVS(0.104)S(0.425)FPDDAT(0.47)S(0.001)PLQENR;NVSSFPDDAT(0.686)S(0.314)PLQENR 201.22 2.292e-12 170494400.0 199729.0 211357.0 228089.0 228242.0 214115.0 200497.0 177282.0 168843.0 219788.0 184423.0 True False 196880.8278341871 210867.61585223515 209336.402869001 245027.67807299245 201521.17666628648 191922.21069133477 186460.79451251178 176688.06217167593 195033.16096975474 216300.26982179936 0.9102199826028368 0.9748837392850229 0.9678046312261395 1.1328126325263506 0.9316732560357472 0.8872952902437494 0.8620460560041323 0.8168647330733417 0.9016778440934646 1.0 17.7226759394146 -6.515712120165897 19.057179138868594 0.8834178663576341 0.9977710726513705 0.3329761933471903 0.06793317513524251 15.651888700387905 41623.46838077201 0.02212850757502228 0.023153470593600373 3.04991601087979e-07 6.515712120165897 0.11435320629373646 NVSSFPDDATS(ph)PLQENR ddPTM_PC-9_AZD4547_30min_R2 3 NVSSFPDDATSPLQENR 17 0 P52292;J3QLL0;J3KS65 P52292 KPNA2 Importin subunit alpha-1 1 NVSSFPDDAT(0.083)S(0.917)PLQENR;NVSSFPDDAT(0.001)S(0.999)PLQENR;NVSSFPDDAT(0.01)S(0.99)PLQENR 300.5 1.3901999999999996e-112 311119000.0 739837.0 601995.0 697870.0 1044167.0 882017.0 743916.0 711788.0 881957.0 630787.0 780625.0 True False 975089.7764344215 796578.1110961526 688615.7878198428 803450.4303693358 759564.164271646 697398.8149195425 775135.753083935 745670.8110056637 664129.1130428166 753295.5563537565 1.29443187100988 1.057457599978288 0.9141375944828496 1.0665806051722229 1.0083215782504173 0.925797064694267 1.0289928654775207 0.9898781490428544 0.8816315288748814 1.0 19.52285649341917 -4.797332043210445 3.1582565718261377 0.9807904197210949 1.3352162697886363 0.7612188628964388 0.0534241960698093 0.15382703954032392 2.3656609128259163 0.01334135193049824 0.13419173647423105 1.5946594717876446e-05 4.797332043210445 0.35442585006754135 NVSSFPDDATS(ph)PLQENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NVSSFPDDATSPLQENR 17 0 P52292;J3QLL0;J3KS65 P52292 KPNA2 Importin subunit alpha-1 1 NVSSFPDDAT(0.402)S(0.598)PLQENR;NVSSFPDDAT(0.248)S(0.752)PLQENR;NVSSFPDDAT(0.035)S(0.965)PLQENR;NVSS(0.001)FPDDAT(0.054)S(0.945)PLQENR 198.67 2.2919e-12 218335000.0 133511.5 123176.8 132347.9 121946.8 144435.9 113581.9 121101.0 120171.6 100465.4 82506.9 True False 156112.3599776752 135404.97865688824 135503.5758682055 115114.51615285988 116134.72223678385 107625.4652144925 109629.43658468542 117017.22283233498 101934.5164131364 97464.74784573872 1.6017315329719044 1.3892713175762688 1.3902829367872815 1.1810887392337601 1.1915561759888287 1.1042501785859598 1.1248111651425008 1.2006107379207787 1.0458603614762556 1.0 16.57259288246818 -1.5228787459714137 0.32254340423913697 1.0555168265282953 6.47292317111019 0.9067487966039537 0.05351952719674503 15.854884169044595 0.2261778177304118 0.04954619872401379 50.80297343855001 0.02999999995226215 1.5228787459714137 5.417406344581894 NVSSFPDDATS(ph)PLQENR ddPTM_PC-9_Lapatinib_30min_R1 2 NVSSFPDDATSPLQENR 17 0 P52292;J3QLL0;J3KS65 P52292 KPNA2 Importin subunit alpha-1 1 NVS(0.002)S(0.012)FPDDAT(0.257)S(0.729)PLQENR;NVSSFPDDAT(0.036)S(0.964)PLQENR 177.66 3.9122e-06 107148200.0 96957.4 112790.0 112986.5 80830.8 94576.3 92710.4 72296.2 75747.5 95879.3 61600.0 True False 95574.76969619052 112528.84168479698 103697.18611050282 86775.3666756444 89013.50797816 88745.39231049803 76039.34348797667 79267.00537984389 85080.36358021101 72247.47792315931 1.322880361274916 1.5575469887610465 1.4353052741964594 1.2010850644217173 1.2320638801098724 1.2283528070680267 1.0524844004776235 1.09715948097386 1.1776239949953746 1.0 16.140659605207617 -6.128131025430892 0.8607330402728433 1.0940539509900489 1.474061386967413 0.7249504282401368 0.08516596495430195 0.34567650536730027 0.5344985747670972 0.04223257788518131 0.0829054733334044 7.445073242415429e-07 6.128131025430892 0.3800074359773642 NVST(ph)GSAENEEK ddPTM_PC-9_Lapatinib_30min_R1 1 NVSTGSAENEEK 12 0 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 NVS(0.164)T(0.556)GS(0.28)AENEEK 163.62 0.001809 18617000.0 31525.0 35495.0 25183.0 28305.0 26768.0 24744.0 29164.0 32153.0 24853.0 28729.0 True False 31075.447719023046 35412.81350830631 23112.55094919118 30386.64412271202 25193.558867912852 23685.75680108126 30673.969219452047 33646.94576029736 22053.7934263077 33694.769371013776 0.9222632562594708 1.0509884521949124 0.6859388380047485 0.9018208075005375 0.7476994007736356 0.7029505541431942 0.9103480982968116 0.9985806814645376 0.6545168237678953 1.0 15.04023703065425 -5.24451347965527 24.97424668807483 0.823820178116348 0.9866258563315975 0.21566217215225358 0.1230916651357429 1205.9006605583247 1779305.4189558795 0.030292988100998428 0.07969732298053689 5.694905479756433e-06 5.24451347965527 0.1628056782152495 NVSTCEVSSSQAIS(ph)SPQR ddPTM_PC-9_Lapatinib_30min_R1 1 NVSTCEVSSSQAISSPQR 18 0 Q9H2X6-3;Q9H2X6 Q9H2X6-3 HIPK2 Homeodomain-interacting protein kinase 2 1 NVSTCEVSSSQAIS(0.672)S(0.328)PQR 137.52 0.00010471 4543500.0 20428.0 19782.0 22092.0 17183.0 21003.0 18363.0 17185.0 17219.0 19323.0 13556.0 True False 20136.692973963596 19736.19599440246 20275.681037586113 18446.695140807664 19767.644833486756 17577.657296243742 18074.755213149212 18019.057601049997 17146.640259789314 15899.13653776541 1.2665274573957315 1.2413376001597847 1.2752693197787845 1.1602325130670466 1.2433156219856616 1.1055730765310003 1.1368387943720106 1.1333356096571103 1.0784636146158437 1.0 13.956660796221987 -6.99287048106481 0.2313158370931931 0.9703046436974428 1.351294379779516 0.8443961538609209 0.03404388826112043 1.271974047108473 0.180929366236264 0.0797003368791297 0.16356797914035315 1.0165518122584582e-07 6.99287048106481 0.3809897360820732 NVSTCEVSSSQAISS(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 2 NVSTCEVSSSQAISSPQR 18 0 Q9H2X6-3;Q9H2X6 Q9H2X6-3 HIPK2 Homeodomain-interacting protein kinase 2 1 NVSTCEVSSSQAIS(0.065)S(0.935)PQR;NVSTCEVSSSQAIS(0.226)S(0.774)PQR 316.32 1.9332999999999993e-156 8338100.0 18145.6 20806.6 23983.0 37563.0 31466.0 24050.3 23530.0 29011.0 21869.0 23711.2 True False 23915.523348073242 27531.926554760797 23664.969749786174 28903.430692564823 27097.48904269608 22546.430939056954 25624.124416350027 24528.016556459446 23024.95069355163 22881.078105127595 1.0452096373340831 1.203261770632694 1.0342593841538834 1.2632023089020283 1.1842750117890466 0.9853745018249097 1.1198827388560735 1.0719781840595517 1.0062878413229923 1.0 14.481867409824739 -6.752388298630353 24.999960176825244 1.0464019164806058 1.149519327497111 0.34913506663967464 0.07397676271539463 237.7513543835656 656691.5870982242 0.02415571427075274 0.023829217492575744 1.7685270277697888e-07 6.752388298630353 0.10311741101650518 NVSTCEVSSSQAISS(ph)PQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NVSTCEVSSSQAISSPQR 18 0 Q9H2X6-3;Q9H2X6 Q9H2X6-3 HIPK2 Homeodomain-interacting protein kinase 2 1 NVSTCEVSSSQAIS(0.007)S(0.993)PQR 324.29 0.0 0.0 9937.2 11164.0 9101.1 12514.0 14608.0 11019.0 11083.0 10636.0 11956.0 10348.0 True False 11619.371691353597 12272.288139694347 9318.10474011396 11812.88115093539 11745.667264405422 10441.144242159127 10033.138006028603 10356.816269773522 12130.83388147022 12224.010485277067 0.9505367903069362 1.003949412058786 0.7622788569542656 0.9663670662883632 0.960868552800427 0.8541504651631907 0.8207730202876371 0.8472519131301103 0.9923775749440765 1.0 13.577430065523538 NVSTCEVSSSQAISS(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 1 NVSTCEVSSSQAISSPQR 18 0 Q9H2X6-3;Q9H2X6 Q9H2X6-3 HIPK2 Homeodomain-interacting protein kinase 2 1 NVSTCEVSSSQAIS(0.028)S(0.972)PQR 285.34 1.0115e-105 4842700.0 16902.0 14321.0 16931.0 11796.0 15578.0 13743.0 14474.0 16349.0 13466.0 14025.0 True False 16660.974380552805 14287.84060437962 15538.998535550008 12663.517190302453 14661.732667526381 13155.243926497718 15223.39289817409 17108.63422495885 11949.317276733584 16449.202562862185 1.0128742908284651 0.8686038456744201 0.9446657657820344 0.7698559940463754 0.8913339483476589 0.7997496459918776 0.92547908264832 1.0400889745005317 0.7264374811525444 1.0 14.00573002512151 -9.820882089047466 12.051732937128177 0.9999993367697947 0.887560127761997 0.11219638891024775 0.0956904504072897 0.0 0.0 0.08879970454409396 0.02153709184464353 1.5104901965891708e-10 9.820882089047466 -0.11243920900779769 NVSTGS(ph)AENEEK ddPTM_PC-9_AZD4547_30min_R2 3 NVSTGSAENEEK 12 0 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 NVS(0.051)T(0.158)GS(0.792)AENEEK;NVST(0.02)GS(0.98)AENEEK;NVST(0.015)GS(0.985)AENEEK 132.23 9.3314e-05 22748300.0 41671.0 42661.0 39029.0 34413.3 33850.0 46358.0 45501.0 49134.0 46708.0 39400.0 True False 54921.51118935499 56450.333968675826 38511.44995890441 26479.84536518493 29150.511793531496 43459.22693158932 49550.50085288321 41541.46928699732 49176.889523728125 38020.61799242665 1.4445191606379162 1.4847295217537024 1.0129096262079573 0.6964601514488656 0.7667027347987349 1.1430436754143762 1.3032534311449964 1.0926037366165904 1.2934268857366733 1.0 15.214494361492866 -6.989925238140924 24.989152270459382 1.1861967009156709 1.0659904997734782 0.026867711331716948 0.24823359651512603 868.6930642986157 2154671.2926073186 0.10000674234786869 0.08810969308935342 1.0234691627708201e-07 6.989925238140924 -0.12020620114219271 NVSTGS(ph)AENEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NVSTGSAENEEK 12 0 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 NVS(0.033)T(0.13)GS(0.837)AENEEK;NVS(0.002)T(0.019)GS(0.98)AENEEK;NVST(0.001)GS(0.999)AENEEK;NVST(0.027)GS(0.973)AENEEK 135.86 6.165e-05 22474300.0 68322.0 110588.0 75785.0 72142.0 76000.0 56362.0 85092.0 52049.0 53917.3 50600.0 True False 79887.56517899009 121566.44578936948 77592.001816213 68100.11762751955 61108.34557056497 53406.27750036958 77031.46974726932 50682.768900474024 54705.73851098985 59773.37945062043 1.3365074204142373 2.033789069761349 1.2981029771005799 1.1393051263527427 1.0223337902627267 0.8934793045203209 1.2887253565929968 0.8479153992345995 0.9152190994351086 1.0 15.867215491307833 -5.5770550416423275 2.8741381053150032 1.0117663299169406 1.688220062545122 0.6361634236654128 0.20010570941495143 0.1467864421275812 2.4431552842997766 0.05356388824528603 0.11036004988014211 2.6481644940935887e-06 5.5770550416423275 0.6764537326281814 NVSTGS(ph)AENEEK ddPTM_PC-9_Lapatinib_30min_R1 2 NVSTGSAENEEK 12 0 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 NVS(0.001)T(0.037)GS(0.962)AENEEK;NVS(0.004)T(0.01)GS(0.986)AENEEK 146.78 0.00012736 20728600.0 46872.0 46350.0 32197.0 36385.0 40204.0 36594.0 38072.0 42899.0 42529.0 33311.0 True False 46203.59668472795 46242.67942273553 29549.88694401414 39060.87427680189 37839.279764105195 35028.95992478046 40043.18187227329 44892.2441504991 37738.936169775894 39068.761965882535 1.1826224932613947 1.1836228509907158 0.7563558571377071 0.9997981075241767 0.9685303004264377 0.8965976437996703 1.0249411513792448 1.1490572491061277 0.9659619161398578 1.0 15.253727918818642 -5.1128699214135525 24.40156191961799 0.9754178861285715 1.183243592167398 0.4507925427988435 0.09388314826972323 15.22000071178489 3260.669258152317 0.024636407608727613 0.0651819249045251 7.711344023521197e-06 5.1128699214135525 0.20782570603882655 NVTELNEPLSNEER ddPTM_PC-9_AZD4547_30min_R2 2 NVTELNEPLSNEER 14 0 P61981 P61981 YWHAG 14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed 0 ; 143.31 0.00075419 21582000.0 29874.0 26642.0 42367.0 47594.0 50297.0 43590.0 41725.0 48771.0 39499.0 34396.0 False True 39373.310582198435 35253.50548729426 41805.18589789399 36621.93861996996 43314.129739416654 40864.310409163 45438.444167964524 41234.562596087155 41586.83650119331 33191.8065093276 1.186235843208284 1.0621146962093573 1.259503181489861 1.1033427363972617 1.3049645166871067 1.2311565626197316 1.3689656860103518 1.2423114898702294 1.2529247689337586 1.0 15.018539531747308 -5.273662176334592 24.386147587336367 1.2335802819202766 1.1241752653464163 0.11452942860326643 0.10187140642922617 848.1164708176611 1692110.2890309407 0.02546139208247458 0.053671358015309686 5.325223301390596e-06 5.273662176334592 -0.10940501657386026 NVTELNEPLSNEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NVTELNEPLSNEER 14 0 P61981 P61981 YWHAG 14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed 0 92.906 0.026477999999999998 0.0 5852.0 5734.0 5093.8 6944.2 8113.2 6565.3 8316.1 7460.0 6537.7 6160.6 False True 6842.6280177314775 6303.233625314174 5215.255510344078 6555.13898740016 6523.476701093511 6221.004110449885 7528.338804649862 7264.1829045233635 6633.301494386745 7277.468012717233 0.9402484498419119 0.8661300351027852 0.7166304958304895 0.9007444589169176 0.8963937305796278 0.8548308422075922 1.0344722630857652 0.9981744875868016 0.9114848025158173 1.0 12.829220877822133 -7.248439198487038 24.30313254150016 0.9858807606699754 0.8593105698964335 0.4883322609918399 0.06189784324611623 474.58088541822224 887204.1694156285 0.024786069085738074 0.019065773869120235 5.64365947418164e-08 7.248439198487038 -0.12657019077354192 NVTELNEPLSNEER ddPTM_PC-9_Lapatinib_30min_R1 2 NVTELNEPLSNEER 14 0 P61981 P61981 YWHAG 14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed 0 ; 228.17 5.8734e-20 36181000.0 47984.0 46985.0 43744.0 42863.0 49381.0 43776.0 40902.0 44012.0 43870.0 40602.0 False True 47299.739360812106 46876.20911924983 40147.537176723155 46015.288006776354 46476.50666678135 41903.80252684014 43019.70542497698 46056.95819370532 38928.898628419905 47620.001601235715 0.9932746276846975 0.9843806707900953 0.8430813907339588 0.9663016896156988 0.9759870874421666 0.8799622242295926 0.9033957156326647 0.9671767460106546 0.8174904938980455 1.0 15.539280048668717 -6.757769450079833 24.999642247664074 0.9109155014284993 0.9490466716947182 0.09256627361549008 0.06025033687702442 256.50642263212916 1747325.814720087 0.019982774093943757 0.01924341555684813 1.746749187523015e-07 6.757769450079833 0.03813117026621893 NVVHELR ddPTM_PC-9_AZD4547_30min_R2 1 NVVHELR 7 0 Q14204 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 92.47 0.0065999 0.0 20246.0 21716.0 24237.0 30433.0 26552.0 21676.0 20325.0 28663.0 22927.0 24719.0 False True 26683.806857039217 28735.272320474513 23915.601543825534 23417.142035162946 22865.713120881785 20320.596293393388 22133.88562525772 24233.791960214996 24138.87441360183 23853.595333878035 1.118649263708334 1.2046516224605892 1.0025994492268189 0.9817028295900024 0.9585856052654163 0.8518881958449714 0.9279056391898333 1.0159387556054071 1.0119595841100997 1.0 14.541919112423146 -5.387960254774616 3.992428874103104 0.9600339823456344 1.1609715088916273 0.7082449201009035 0.049799529529304616 0.12476612859631754 3.3680891553882595 0.014545136619090782 0.032612107521758554 4.092981156549081e-06 5.387960254774616 0.20093752654599284 NVVHELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NVVHELR 7 0 Q14204 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ; 94.11399999999999 0.006181399999999999 1849800.0 25698.0 30089.0 28390.0 31103.0 32276.0 27047.0 30954.0 25615.8 24910.0 26345.0 False True 30048.163841364225 33076.03706872657 29066.925269674575 29360.39974728655 25951.749495204655 25628.607706477727 28021.81303244693 24943.412392183567 25274.261624909926 31121.13995309475 0.9655225961083785 1.0628157297122858 0.9339929486350355 0.9434230170083114 0.833894566019069 0.8235112127995545 0.9004108806644271 0.8014941750134427 0.8121251876699523 1.0 14.925607286099638 -5.850672620814425 1.6565237431591164 0.8524431951729536 1.0096533408385437 0.4599587765722739 0.06187517600297054 0.28904075797354695 1.6166026958078776 0.01911376807475918 0.037353434438038194 1.4103515468041213e-06 5.850672620814425 0.1572101456655901 NVVHELR ddPTM_PC-9_Lapatinib_30min_R1 1 NVVHELR 7 0 Q14204 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 77.923 0.021026 0.0 16337.0 24871.0 27978.0 25102.0 26793.0 23820.0 26479.0 24520.0 24796.0 20580.0 False True 16104.031384161131 24813.412727569685 25677.75683820316 26948.08481781725 25217.08841706473 22801.274127132052 27849.953057257942 25659.288714660874 22003.21336654433 24137.22557887372 0.6671865136917932 1.028014286334872 1.0638238746327913 1.1164532862220815 1.0447384822527477 0.9446518222495724 1.1538174910058352 1.0630587442957549 0.911588338711256 1.0 14.558972236519324 -4.7615818246325645 5.825773656939635 1.0436483465851496 0.6518787601317624 0.7208638798311795 0.06882499031251126 0.07207500085488457 8.804321817507281 0.017079504247144404 0.11323298928861382 1.7314827744995766e-05 4.7615818246325645 -0.3917695864533872 NVY(ph)ATTVGTPYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NVYATTVGTPYK 12 0 Q13439-3;Q13439-4;Q13439;H0Y6I0;Q13439-5 Q13439-3;Q13439-5 GOLGA4 Golgin subfamily A member 4 1 NVY(0.989)AT(0.006)T(0.006)VGTPYK;NVY(0.947)AT(0.044)T(0.009)VGTPYK 88.596 0.022751 5878300.0 20505.7 16704.2 28544.0 25209.0 32918.0 30748.0 31342.0 26019.0 27334.0 19899.1 True False 23976.91000396383 18362.482581788092 29224.59721372282 23796.621458680725 26467.954203840207 29135.520751239575 28373.058863570182 25336.028819409297 27733.708039152483 23506.649308811084 1.0200054328873012 0.7811612084970875 1.2432481052400972 1.0123357500280123 1.125977329058086 1.239458689687373 1.2070226807244282 1.077823916397668 1.1798239585238104 1.0 14.520781288167269 -5.263788573971487 24.99999359162755 1.1399889167210364 0.9005833188735909 0.48145396138671526 0.09752610123547403 150.39449097704946 1600509.3379532944 0.024232818094417963 0.054598674059317946 5.447677956544417e-06 5.263788573971487 -0.23940559784744553 NVY(ph)ATTVGTPYK ddPTM_PC-9_Lapatinib_30min_R1 2 NVYATTVGTPYK 12 0 Q13439-3;Q13439-4;Q13439;H0Y6I0;Q13439-5 Q13439-3;Q13439-5 GOLGA4 Golgin subfamily A member 4 1 NVY(0.979)AT(0.017)T(0.004)VGTPYK;NVY(0.879)AT(0.12)TVGTPYK 205.07 1.2432e-07 18878900.0 114201.0 105038.0 129586.0 63234.0 109598.0 118444.0 126243.0 90586.0 103594.0 80025.0 True False 112572.47279810165 104794.79096451528 118931.93929642581 67884.43930244028 103151.66111795853 113378.42622644943 132779.24482825692 94794.95626045158 91926.1528268186 93857.21462338998 1.199401380595069 1.1165342098102233 1.2671582016752818 0.7232735338975521 1.0990275125025104 1.2079883968578224 1.4146940686557221 1.0099911513550062 0.979425536925212 1.0 16.518180026058296 -7.966226580153398 24.99995388245735 0.9913766774533708 1.1401035317462873 0.14675141427605476 0.1660947418727821 375.9062882830222 278255.2099996279 0.09599353358395515 0.04611345646347925 1.0808698926396373e-08 7.966226580153398 0.14872685429291654 NVYSS(ph)SR ddPTM_PC-9_AZD4547_30min_R2 1 NVYSSSR 7 0 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 1 NVYS(0.096)S(0.901)S(0.003)R 91.265 0.015373 24140000.0 31456.0 36278.0 54749.0 65659.0 41261.0 58446.0 42710.0 63469.0 56653.0 45620.0 True False 41458.35367455425 48004.154045043964 54022.99248763888 50522.33197143768 35532.6223667032 54791.36238068231 46511.10725976666 53661.324422526806 59647.56192060821 44022.85768564731 0.9417460804247345 1.0904370267788106 1.2271577841084111 1.1476386274648722 0.8071402956261933 1.244611669054502 1.056521764031929 1.2189423232290963 1.354922534709849 1.0 15.425965178461265 -7.766398210837806 24.7512611080868 1.2151993775165266 1.0793363470765664 0.1128456077032296 0.1460633981810176 215.35891630016548 1074900.136907835 0.07565884321551797 0.03815358048919588 1.712386475745875e-08 7.766398210837806 -0.13586303043996018 NVYSS(ph)SR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NVYSSSR 7 0 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 1 NVYS(0.288)S(0.711)S(0.001)R;NVYS(0.268)S(0.729)S(0.003)R 85.86200000000001 0.019 40410000.0 57084.0 73978.0 96412.0 80399.0 98490.0 71129.0 96144.0 65238.0 68086.0 52115.0 True False 66747.19373960761 81322.0469364304 98710.82772454599 75894.50468707496 79191.59151638075 67398.87002455174 87036.54429771844 63525.57162537469 69081.62894394297 61563.03695788697 1.0842089188235942 1.3209557382956894 1.6034106275827567 1.2327933844295502 1.286349657677753 1.0947944311236115 1.4137792512941973 1.0318784576665738 1.122128347748653 1.0 15.909776782365864 -7.92129225297306 0.7064245523572755 0.9975404673814231 1.3180724532568133 0.30041886589902955 0.15119985869864547 0.8226330676478959 0.8308703911703137 0.14492237223066748 0.06702952917295078 1.198692386812522e-08 7.92129225297306 0.3205319858753902 NVYSS(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 2 NVYSSSR 7 0 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 1 NVYS(0.028)S(0.97)S(0.002)R;NVYS(0.104)S(0.892)S(0.004)R 106.68 0.010019 51487000.0 78383.0 124547.0 125009.0 102775.0 112143.0 90657.0 120272.0 103556.0 118095.0 71944.0 True False 77265.24404631817 124258.61907364489 114731.24256869483 110333.41634734947 105546.96922162104 86779.8114417888 126499.09566458433 108367.58980976457 104793.89750451891 84379.42454064582 0.9156882079599781 1.4726175219859332 1.359706388059431 1.3075867363162867 1.2508614487028025 1.0284475381790108 1.4991699262377565 1.2842892731220699 1.241936622286863 1.0 16.36460362810236 -6.5096352220595834 24.331688753685118 1.2346832782285118 1.28484805436383 0.005441820057423885 0.1864760459736718 2893.1637120716505 5315481.971971402 0.05835466594073485 0.06331552882186334 3.092892161688385e-07 6.5096352220595834 0.050164776135318334 NWGAVVRS(ph)PEGTPQK ddPTM_PC-9_AZD4547_30min_R2 1 NWGAVVRSPEGTPQK 15 1 C9J0I9;Q86WB0;Q86WB0-3;F8WAU5;F8WBD7;F8WDK5;F8WF13 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 NWGAVVRS(0.999)PEGT(0.001)PQK 55.031000000000006 0.033973 10022000.0 37644.0 19110.0 48199.0 125560.0 85716.0 46860.0 38264.0 47434.0 31745.0 54328.0 True False 49614.008956158425 25286.93378358208 47559.84976733287 96614.0818826622 73815.81296585943 43929.83679223166 41669.42187280994 40104.165224883596 33422.97589129802 52425.99325615622 0.9463627844634571 0.4823358073547365 0.9071807096711146 1.8428660266025025 1.408000275840105 0.8379400000604303 0.7948236987940487 0.7649671991703141 0.6375268033166595 1.0 15.677994669245784 -6.970351465028499 24.073646058691526 0.7849773414864225 1.1119282632589267 0.172457846986372 0.34001802319139307 279.51710097289197 226957.35694811805 0.13662526070379452 0.12049007424041788 1.0706524988833158e-07 6.970351465028499 0.3269509217725042 NWGAVVRS(ph)PEGTPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NWGAVVRSPEGTPQK 15 1 C9J0I9;Q86WB0;Q86WB0-3;F8WAU5;F8WBD7;F8WDK5;F8WF13 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 NWGAVVRS(1)PEGTPQK 54.288000000000004 0.035341000000000004 3261000.0 29983.0 13298.0 16089.0 41174.0 30448.0 38495.0 29222.0 57073.0 37798.0 30063.0 True False 35058.52970875647 14618.137556579664 16472.622777872286 38867.15426790907 24481.932972796847 36476.254433425485 26453.880611041033 55574.89422384204 38350.724243209406 35513.18392142293 0.9871975936127709 0.4116256539803359 0.463845281074203 1.0944429638836999 0.6893758956382504 1.0271186755356394 0.7449030948498826 1.564908805327283 1.0799010397959492 1.0 15.116067089999301 -6.962409990266657 0.8746799181658483 1.1993562257310315 0.6631372183786305 0.3159051759620768 0.2670901017278001 0.6497413032349575 1.0420689979695996 0.18308918399476867 0.13954547907459885 1.0904104620645212e-07 6.962409990266657 -0.536219007352401 NWTEDMEGGIS(ph)SPVK ddPTM_PC-9_AZD4547_30min_R2 2 NWTEDMEGGISSPVK 15 0 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 NWTEDMEGGIS(0.5)S(0.5)PVK;NWTEDMEGGIS(0.886)S(0.114)PVK 131.24 8.8697e-06 27465000.0 139248.0 143617.0 160106.0 190117.0 176816.0 178761.0 165537.0 177844.0 156082.0 165527.0 True False 183525.96746167145 190038.3866664945 157982.88982859798 146288.46292836958 152268.1504663236 167583.04641092886 180269.47231233917 150362.29624856042 164332.17587228157 159731.95011249732 1.1489621665071783 1.1897330905473371 0.9890500286093828 0.915837206177852 0.953272969866598 1.0491516962818153 1.1285749168239512 0.9413413918922422 1.028799659407804 1.0 17.28529338867991 -5.2633371932280975 24.952145217301904 1.0002236317531792 1.169347638832483 0.5763087514739917 0.05782143679932841 113.30396025075233 1489728.2508948685 0.016277490170529547 0.036847689012614336 5.4533429035580594e-06 5.2633371932280975 0.16912400707930386 NWTEDMEGGIS(ph)SPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NWTEDMEGGISSPVK 15 0 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 NWT(0.001)EDMEGGIS(0.971)S(0.028)PVK;NWTEDMEGGIS(0.941)S(0.059)PVK 134.81 1.4045999999999999e-05 29612000.0 105727.0 110317.0 92655.0 119613.0 110307.0 106342.0 133594.0 117153.0 98608.0 92844.0 True False 123624.49289656477 121268.54270034593 94864.24659604409 112911.47140057823 88693.13519542516 100765.23831560808 120939.00918319827 114077.85788386382 100049.95545199198 109675.88224730024 1.1271802912677995 1.1056992678381765 0.8649508410804624 1.0295013733829128 0.8086840368007016 0.9187547549277955 1.1026946554257173 1.0401362227170226 0.912232966828537 1.0 16.742886786070322 -5.145052292696454 7.2163045727933905 0.9619886342642012 1.1210396690419624 0.3627540056877443 0.08322990176070505 0.28258263488123403 15.705500058237114 0.02213030541779826 0.05964109853226024 7.160571857338263e-06 5.145052292696454 0.15905103477776117 NWTEDMEGGIS(ph)SPVK ddPTM_PC-9_Lapatinib_30min_R1 3 NWTEDMEGGISSPVK 15 0 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 NWTEDMEGGIS(0.817)S(0.183)PVK;NWT(0.023)EDMEGGIS(0.688)S(0.289)PVK;NWT(0.005)EDMEGGIS(0.906)S(0.089)PVK 121.95 5.0789e-05 33294700.0 177947.0 171684.0 164836.0 167752.0 195326.0 170839.0 169478.0 175051.0 176762.0 137617.0 True False 175409.44314851676 171286.47624623388 151283.82036536044 180089.04168426737 183837.30870569122 163532.61421516014 178252.7415777774 183184.50851509362 156853.20217362096 161403.91508687407 1.0867731619403678 1.0612287573943955 0.9372995709796347 1.1157662537946258 1.1389891540533115 1.0131886461808581 1.1043892056883169 1.1349446413149047 0.9718054366227502 1.0 17.300316048144907 -4.771501055724197 7.088887488544709 1.0586223083495336 1.0872306716029667 0.01620255258401282 0.06738317133695033 0.6643406927809298 190.2568725996794 0.016759794394929736 0.08785081337379223 1.6923841304236397e-05 4.771501055724197 0.028608363253433078 NWTEDMEGGIS(ph)SPVKK ddPTM_PC-9_AZD4547_30min_R2 1 NWTEDMEGGISSPVKK 16 1 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 NWTEDMEGGIS(0.956)S(0.044)PVKK 157.68 3.2344000000000003e-15 0.0 36397.0 35035.0 41703.0 51741.0 49186.0 45453.0 40252.0 46879.0 48904.0 48355.0 True False 47970.48889536975 46359.378603233796 41149.99097174387 39812.91184048126 42357.37291216072 42610.81672465442 43834.35002154362 39634.92772225234 51488.96560050524 46662.10616811649 1.0280395128873814 0.9935123467468011 0.8818717017077348 0.8532172057780971 0.9077467004929767 0.9131781701223283 0.9393993032293723 0.8494028876333551 1.103442811068114 1.0 15.509963806668408 -8.266330567207383 24.998140714433223 1.05172140908006 0.9196009635347561 0.4470885038520125 0.058227011709231336 411.6309646013111 2103746.24253647 0.0525329448721173 0.015247254078632682 5.415884984465638e-09 8.266330567207383 -0.1321204455453039 NWTEDMEGGIS(ph)SPVKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NWTEDMEGGISSPVKK 16 1 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 NWTEDMEGGIS(0.5)S(0.5)PVKK 62.361999999999995 0.014052 289520000.0 113480.0 109460.0 99156.0 122740.0 143030.0 117370.0 127830.0 123910.0 117610.0 98658.0 True False 132689.92266783435 120326.46540406164 101520.25509122417 115863.27572844902 115004.29824944612 111214.9105819237 115721.01699094404 120657.4937934971 119329.82375374009 116543.91442370183 1.1385401230426568 1.0324560145337847 0.8710901430866795 0.9941598092133896 0.986789390232266 0.9542747138009777 0.9929391642898994 1.0352963892635365 1.0239043741049398 1.0 16.830514147629756 -7.69973010993453 8.286085538316375 1.0221303618556281 0.9902746634574807 0.023999668061314594 0.06321524199134085 0.975204187954344 117.08564255009937 0.03147470268418452 0.018038363092513766 1.996502645800636e-08 7.69973010993453 -0.03185569839814739 NWTEDMEGGIS(ph)SPVKK ddPTM_PC-9_Lapatinib_30min_R1 1 NWTEDMEGGISSPVKK 16 1 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 NWT(0.001)EDMEGGIS(0.577)S(0.422)PVKK 63.302 0.015572999999999998 62612000.0 79911.0 59266.0 64643.0 61202.0 67310.0 65946.0 57654.0 76786.0 68356.0 52437.0 True False 78771.45448611735 59128.7732182922 59328.30206919606 65702.99924388707 63350.95813655154 63125.64330763431 60639.042016811414 80353.75788107455 60657.02745940886 61500.66558208946 1.2808227966407175 0.9614330618807478 0.9646773983284167 1.0683298891487352 1.030085732194107 1.0264221160887417 0.9859900123498994 1.30655102868473 0.986282455406039 1.0 15.908314403444965 NWTEDMEGGISS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 2 NWTEDMEGGISSPVK 15 0 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 NWTEDMEGGIS(0.162)S(0.838)PVK;NWTEDMEGGIS(0.09)S(0.91)PVK 118.71 9.5675e-05 30302000.0 88339.0 86619.0 107887.0 114096.0 107631.0 109604.0 96107.0 96345.0 95634.0 97973.0 True False 116428.96443465301 114616.89782313415 106456.34788788646 87792.92996562773 92688.29349629527 102750.44455347313 104660.33681607121 81457.09403785087 100689.01799931955 94542.99509066009 1.2314922361303005 1.212325648380661 1.1260098940783747 0.9286032231308146 0.980382453585416 1.086811819902074 1.1070131289548137 0.8615878305922003 1.0650077026094409 1.0 16.528682949069342 -5.526782450877794 3.923842039885157 1.005315554607354 1.2156515590753278 0.6155386941439244 0.0697371172138537 0.14310337868419581 4.971849928539999 0.019694020973748415 0.03933922319995212 2.9731549875286964e-06 5.526782450877794 0.21033600446797385 NWTEDMEGGISS(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NWTEDMEGGISSPVK 15 0 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 NWTEDMEGGIS(0.108)S(0.892)PVK;NWTEDMEGGIS(0.206)S(0.794)PVK 95.854 0.0024285 15039400.0 49368.0 54618.0 56565.0 65602.0 76101.0 60010.0 63282.0 65636.0 60839.0 58221.0 True False 57725.02733755424 60040.114082213004 57913.724123957065 61926.53262455365 61189.55534559954 56862.969958432615 57287.47083799531 63913.124547090585 61728.65527891994 68776.00642281763 0.8393192675753118 0.8729805233688831 0.8420629102527125 0.9004089630305787 0.8896933469707663 0.8267849925576275 0.8329572160064995 0.9292939190764978 0.8975318354402211 1.0 16.069617725695217 -8.646914657027237 1.0117900406465958 0.9984026900513473 0.86087853588217 0.6725231555738487 0.029033017402037595 0.4205969452551401 0.9074984839043042 0.028494844084160868 0.009328509972059073 2.2546822350033427e-09 8.646914657027237 -0.1375241541691773 NWTEDMEGGISS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 4 NWTEDMEGGISSPVK 15 0 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 NWTEDMEGGIS(0.222)S(0.778)PVK;NWTEDMEGGIS(0.358)S(0.642)PVK;NWTEDMEGGIS(0.035)S(0.965)PVK;NWTEDMEGGIS(0.082)S(0.918)PVK 174.4 6.9404e-05 18462500.0 145833.0 136310.0 147046.0 136549.0 157122.0 144509.0 137064.0 140411.0 144471.0 115293.0 True False 143753.39467750344 135994.38256986174 134956.44549397475 146591.26897411075 147880.39287373735 138328.68693693218 144160.5032606973 146935.0076555569 128199.15463292578 135221.24143173397 1.0630977289916164 1.0057176012432787 0.9980417578262444 1.0840846262169312 1.0936180684925476 1.0229804539012977 1.0661084141390336 1.0866266727016893 0.9480696470136072 1.0 17.044962271775454 -8.265801355058771 24.993112529376344 0.9740348199885814 1.0510458965864629 0.46024028886583557 0.03397382947446592 372.65235871793993 2135170.049715418 0.030685567149742837 0.008990857259222565 5.422488566232714e-09 8.265801355058771 0.07701107659788142 NWTEDMEGGISS(ph)PVKK ddPTM_PC-9_AZD4547_30min_R2 4 NWTEDMEGGISSPVKK 16 1 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 NWTEDMEGGIS(0.249)S(0.75)PVKK;NWTEDMEGGIS(0.142)S(0.858)PVKK;NWTEDMEGGIS(0.227)S(0.773)PVKK;NWT(0.001)EDMEGGIS(0.324)S(0.675)PVKK 100.39 0.00081728 157653000.0 457854.0 401216.0 492961.0 613406.0 600957.0 545050.0 478383.0 516703.0 473402.0 553889.0 True False 603442.0480451859 530901.2257934941 486424.0150450043 471994.72372822784 517524.49382290395 510967.9373368729 520958.16024933266 436858.4240037322 498425.0632506622 534497.5147006895 1.1289894367106725 0.9932716452213829 0.9100585160202184 0.8830625227369631 0.9682449021539602 0.9559781351331582 0.9746690039168121 0.8173254542602809 0.9325114701978974 1.0 19.027823714174296 -4.826893119803543 2.538624908943629 0.9262085632428502 1.1611609797134836 0.5956213005521864 0.04964975400266995 0.3075909037288391 2.7687500524937323 0.013118728154209116 0.15185550132013478 1.4897276556905453e-05 4.826893119803543 0.23495241647063347 NWTEDMEGGISS(ph)PVKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NWTEDMEGGISSPVKK 16 1 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 NWTEDMEGGIS(0.096)S(0.904)PVKK;NWTEDMEGGIS(0.195)S(0.805)PVKK 86.54799999999999 0.0042886 67920000.0 126682.0 124171.0 130740.0 149794.0 168772.0 140412.0 155781.0 158313.0 124510.0 119154.0 True False 148126.7605164485 136497.87626244966 133857.33743421108 141401.52781870053 135702.3381399394 133048.54753880107 141024.29592322832 154157.4514964888 126330.72320022217 140755.67697745512 1.052367930709992 0.9697504157101426 0.9509906833502072 1.0045884532341018 0.9640985078113397 0.9452446281091135 1.0019084057676495 1.095213030172703 0.8975177833889897 1.0 17.10283358489192 -7.498180496104865 24.644700129268784 1.007531379452321 0.9790709541140271 0.01486131979492833 0.053023714439232435 1963.9685037418612 1959716.966213814 0.02145122173649355 0.014384467415387575 3.175554011845664e-08 7.498180496104865 -0.02846042533829396 NWTEDMEGGISS(ph)PVKK ddPTM_PC-9_Lapatinib_30min_R1 4 NWTEDMEGGISSPVKK 16 1 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 NWTEDMEGGIS(0.021)S(0.979)PVKK;NWTEDMEGGIS(0.011)S(0.989)PVKK;NWTEDMEGGIS(0.171)S(0.829)PVKK;NWTEDMEGGIS(0.285)S(0.715)PVKK 125.59 1.4300000000000002e-05 426777000.0 374470.0 325957.0 304647.0 297327.0 344978.0 338266.0 301990.0 301671.0 320047.0 271378.0 True False 369129.98913061275 325202.26659323764 279600.09963142796 319193.41943379637 324687.0722928436 323799.15171655983 317625.564551582 315687.7359641299 283999.9366156803 318285.325711545 1.1597455468781088 1.021731887469928 0.8784573998388584 1.0028530807074478 1.0201132319467985 1.0173235319369134 0.9979271392468752 0.9918388014225662 0.8922809619977994 1.0 18.279961118651613 -4.810341735317448 3.896938506866624 0.9782054747732747 1.171585700377817 0.5758270392241902 0.047467583653538065 0.16494765210988585 4.445455542298318 0.012210395565509152 0.08506728373426253 1.5475983737470905e-05 4.810341735317448 0.19338022560454227 NYADHVR ddPTM_PC-9_AZD4547_30min_R2 2 NYADHVR 7 0 Q6P587;Q6P587-2;Q6P587-3 Q6P587 FAHD1 Acylpyruvase FAHD1, mitochondrial 0 ; 155.75 0.00039451 3247000.0 11544.4 9712.0 12435.2 17599.3 15459.0 10772.2 11349.3 12281.2 10444.4 12181.0 False True 15215.27906156294 12851.214071488694 12270.301122984667 13542.053291474489 13312.784691763765 10098.612631098547 12359.365713492622 10383.422733900581 10996.469661334804 11754.546897607845 1.29441646658957 1.0932972732538104 1.0438769975456716 1.1520693574526824 1.1325646839244 0.8591239389375107 1.05145403061073 0.8833537204240259 0.935507744970815 1.0 13.520931308062044 -6.743730219547435 24.863062633105336 0.9451953938012857 1.1354399591340376 0.6127743938876749 0.07831928722745242 159.87885289629847 224464.03369080115 0.02548103031280158 0.025426947563125094 1.8041381098109657e-07 6.743730219547435 0.1902445653327519 NYADHVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NYADHVR 7 0 Q6P587;Q6P587-2;Q6P587-3 Q6P587 FAHD1 Acylpyruvase FAHD1, mitochondrial 0 138.83 0.0025228 1225200.0 3686.2 3499.1 2328.2 3422.0 4073.6 4226.9 4425.1 2998.0 2990.2 2965.9 False True 4310.200854231332 3846.4675232537174 2383.7131177476695 3230.276434273688 3275.407322582279 4005.233922967822 4005.9224930503633 2919.30567664357 3033.9260180973797 3503.594191948518 1.2302226279905497 1.097863311936395 0.6803622186683588 0.9219893221929265 0.9348706337364564 1.1431786056079507 1.1433751380956811 0.8332316805845609 0.8659467540703014 1.0 11.77461996737293 -5.008436032309896 22.51417254769707 0.944124459666117 1.197133430144858 0.33731731850433366 0.1311851502278282 126.42270727604736 337429.2317005917 0.035620502942138546 0.11540800908893195 9.807627612604204e-06 5.008436032309896 0.25300897047874094 NYADHVR ddPTM_PC-9_Lapatinib_30min_R1 1 NYADHVR 7 0 Q6P587;Q6P587-2;Q6P587-3 Q6P587 FAHD1 Acylpyruvase FAHD1, mitochondrial 0 113.41 0.0075758 1170100.0 5801.3 5699.6 4691.9 4253.1 4402.1 4688.8 3624.1 4472.9 4768.3 3711.9 False True 5718.572398171875 5686.402926382379 4306.150093257755 4565.887161925686 4143.177132861594 4488.270954126645 3811.738165142509 4680.727263124254 4231.243841574985 4353.496969204146 1.3135583735613063 1.306169032988186 0.9891244036044323 1.0487861124571696 0.9516894492334975 1.0309576383941152 0.8755577854093063 1.0751649297644805 0.9719184075482404 1.0 12.08795900363512 -5.26035138249376 19.794299643211726 0.9932767259824697 1.3098644779632582 0.8546399079659347 0.05228766112496341 1.6153206429991807 29361.484000885826 0.012808997594648637 0.030119310282728743 5.490964267031754e-06 5.26035138249376 0.3165877519807885 NYDIGAALDTIQYSK ddPTM_PC-9_Lapatinib_30min_R1 1 NYDIGAALDTIQYSK 15 0 Q13501;Q13501-2 Q13501 SQSTM1 Sequestosome-1 0 189.1 1.0301e-06 3954100.0 47109.0 47630.0 49149.0 50821.0 45499.0 43351.0 48781.0 46869.0 43903.0 51055.0 False True 46437.21702126745 47519.715661378475 45108.15894062647 54558.54587388615 42822.83827447575 41496.97878611678 51306.6414927339 49046.70484369663 38958.181820914484 59879.788723488746 0.7755073625209995 0.7935852259067533 0.7533119254799928 0.9111345754044844 0.7151467830359569 0.6930047628881991 0.8568273633972944 0.8190861372304296 0.6506065343819851 1.0 15.869781510629934 -10.715923545207056 4.617221764892732 1.0000417603962626 0.7778449642366454 0.4592150518931757 0.0734021826031316 3.118808131726709e-05 5.450618263021127e-06 0.07024678121789905 0.01703414842455964 1.9234303068305444e-11 10.715923545207056 -0.22219679615961718 NYDPYKPLDIT(ph)PPPDQK ddPTM_PC-9_AZD4547_30min_R2 2 NYDPYKPLDITPPPDQK 17 1 Q9UKK3 Q9UKK3 PARP4 Poly [ADP-ribose] polymerase 4 1 NYDPY(0.001)KPLDIT(0.999)PPPDQK;NYDPY(0.001)KPLDIT(0.999)PPPDQK 119.27 7.3013e-05 39393000.0 200727.0 201814.0 194430.0 277321.0 260751.0 245953.0 199928.0 216222.0 212956.0 244302.0 True False 264554.0106190311 267046.42881213175 191851.731161695 213388.92801673926 224550.22453988597 230573.52002901773 217721.20468814435 182809.8581872657 224212.41940170954 235749.06133974183 1.1221847888411227 1.1327571244378647 0.8137963734464857 0.9051528214113268 0.9524967915621219 0.9780463969556784 0.923529465826304 0.7754425707927439 0.9510638902548729 1.0 17.846892501103056 -5.246236339570321 24.699841518624925 0.9083304648789701 1.1274710154488738 0.6269842686436157 0.06628221023858469 432.9968321667485 703471.2471233398 0.017123739863951635 0.04490012489265785 5.672358362132912e-06 5.246236339570321 0.21914055056990378 NYDPYKPLDIT(ph)PPPDQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 NYDPYKPLDITPPPDQK 17 1 Q9UKK3 Q9UKK3 PARP4 Poly [ADP-ribose] polymerase 4 1 NY(0.003)DPY(0.121)KPLDIT(0.876)PPPDQK;NYDPY(0.009)KPLDIT(0.991)PPPDQK;NYDPY(0.001)KPLDIT(0.999)PPPDQK;NYDPY(0.003)KPLDIT(0.997)PPPDQK 95.87299999999999 0.0011587 36621100.0 211321.0 195244.0 184121.0 236309.0 256623.0 217214.0 236549.0 205363.0 197065.0 187337.0 True False 247093.47151999865 214626.53399735608 188511.14292278053 223069.37285411512 206339.5653336193 205822.9154566071 214141.36625354728 199972.43885008487 199946.70281464758 221299.7151411237 1.1165557595156692 0.9698455050449923 0.8518363559689457 1.007996656081834 0.932398693789713 0.9300640776936969 0.9676531491104201 0.9036271859751904 0.9035108910426783 1.0 17.7556420685276 -4.790199406366885 4.016394758203887 0.9354969816172072 1.1308492070666523 0.5926524022054942 0.044341645230953255 0.1426886688347487 4.315332587870989 0.010607598536780878 0.07925258008688879 1.6210656139732982e-05 4.790199406366885 0.19535222544944508 NYDPYKPLDIT(ph)PPPDQK ddPTM_PC-9_Lapatinib_30min_R1 2 NYDPYKPLDITPPPDQK 17 1 Q9UKK3 Q9UKK3 PARP4 Poly [ADP-ribose] polymerase 4 1 NYDPY(0.004)KPLDIT(0.996)PPPDQK;NYDPY(0.004)KPLDIT(0.996)PPPDQK 104.18 0.00058043 40813000.0 89122.0 71236.0 71127.0 70141.0 65440.0 74839.0 63407.0 68360.0 69504.0 51874.0 True False 87851.10393702697 71071.0574187267 65279.212618159865 75299.40312351685 61590.947859990134 71638.31042822982 66689.90420716618 71536.25516044928 61675.72761043301 60840.351782239806 1.443961143608509 1.1681565825441758 1.0729591579583178 1.2376556169995363 1.0123371423037932 1.1774802138659246 1.0961459336373192 1.1758027865534426 1.013730621268976 1.0 15.892740874377566 -4.764905808706747 3.2372960408336815 1.1092880602613218 1.4988818511381814 0.6479897910901963 0.07590298390736588 0.20888330644155742 3.2735895544023466 0.017682763210436315 0.21205445414362678 1.7182810134926312e-05 4.764905808706747 0.38959379087685964 NYEGS(ph)PIKVTLATLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NYEGSPIKVTLATLK 15 1 E5RI98 E5RI98 NPM1 1 NY(0.193)EGS(0.807)PIKVT(0.001)LATLK 52.372 0.040788 2484900.0 9100.6 15182.0 10273.0 12027.0 12907.0 10960.0 11976.0 11183.0 8735.8 6879.0 True False 10641.151834956778 16689.16862565744 10517.94728056945 11353.166182060097 10377.966003674755 10385.238306022691 10841.546581268472 10889.458099367928 8863.544548490092 8126.108245865959 1.3095016104874446 2.053771389785241 1.2943400410547452 1.3971221941125207 1.277113925839518 1.2780088563681185 1.3341622155702828 1.3400582135867785 1.0907490129730049 1.0 12.988348867140747 -1.8307641894322104 0.12559693350446235 0.8774651873469999 3.2780865831466834 0.3983661844179448 0.20539980878139652 77.68763212997685 0.718314996793898 1.2233657530635569 32.45259833855366 0.014765080209785715 1.8307641894322104 2.400621395799684 NYFGIPSKVPPMPTTIIT(ph)S(ph)PS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 NYFGIPSKVPPMPTTIITSPSK 22 1 K7EML6 K7EML6 PPP1R13L 3 NY(0.001)FGIPS(0.002)KVPPMPT(0.01)T(0.021)IIT(0.985)S(0.985)PS(0.997)K 47.726000000000006 0.021125 4850500.0 4790.9 6836.9 8089.2 10355.0 8645.6 10964.0 5493.6 10327.0 9319.0 9943.9 True False 6314.306543089456 9046.794222133554 7981.931922610611 7967.814733155201 7445.307673918936 10278.41934677823 5982.519757486636 8731.199440851984 9811.583314884438 9595.767087687595 0.658030409178167 0.942790101037526 0.8318180140962667 0.8303468248389196 0.775894996812925 1.0711409783972927 0.623454039975903 0.9099011429794973 1.0224907738198188 1.0 13.228182425044992 -14.522872016400834 0.03542588452886738 1.8925800032637945 0.31001324466585356 0.2000630511471707 0.12805341916683782 1933.7997199300808 5.117857386412239 193.07561172405238 66.31448018967747 3.0000464818130017e-15 14.522872016400834 -1.5825667585979408 NYGS(ph)PLISGSTPK ddPTM_PC-9_Lapatinib_30min_R1 3 NYGSPLISGSTPK 13 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 NYGS(0.999)PLIS(0.001)GSTPK;NYGS(0.91)PLIS(0.088)GS(0.002)TPK;NYGS(0.995)PLIS(0.003)GS(0.001)T(0.001)PK 125.36 0.0010749000000000002 0.0 178327.0 138076.0 189385.0 142902.0 139734.0 173507.0 139806.0 159428.0 168399.0 102610.0 True False 175784.02427883336 137756.29350536392 173814.49634724134 153411.4897870975 131515.1208476141 166086.51007457194 147044.4706039881 166835.6069005288 149432.13129991537 120346.00178076953 1.460655291224826 1.1446686343291252 1.4442897460264086 1.2747535233165646 1.092808393312401 1.3800750138515314 1.2218475763894037 1.3862995399252889 1.241687543323052 1.0 16.87682868681945 -8.554247043006455 21.231518417495895 0.9999999967461521 1.2938319780348875 0.37435408626894773 0.1160437827979374 1498.7911800692762 1014451.1315181131 0.10522839013706471 0.027169853520928492 2.7909557891718364e-09 8.554247043006455 0.29383198128873533 NYGSPLIS(ph)GSTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NYGSPLISGSTPK 13 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 NYGS(0.003)PLIS(0.792)GS(0.077)T(0.128)PK 69.352 0.030713 7092800.0 49434.0 53515.0 39677.0 52517.0 45361.0 42191.0 50573.0 45727.0 45270.0 45953.0 True False 57802.19983399483 58827.615531686024 40623.050155860416 49574.64275241127 36472.83767666309 39978.42968698938 45782.359323187244 44526.71470176137 45931.9881075742 54283.91513625214 1.064812655625738 1.0837025182142674 0.7483441467679133 0.9132473703854883 0.6718903304066517 0.7364691656201268 0.8433872024203475 0.8202561401475873 0.8461436134863398 1.0 15.728237156016638 -5.2541881585506784 24.885943468072398 0.8115880031344886 1.0742576271748219 0.5647402774987329 0.08800602872073429 343.1056741375479 1177519.282810963 0.02172880799011188 0.05498913142688304 5.5694439989397705e-06 5.2541881585506784 0.2626696240403332 NYGSPLISGS(ph)TPK ddPTM_PC-9_AZD4547_30min_R2 1 NYGSPLISGSTPK 13 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 NYGS(0.014)PLIS(0.073)GS(0.457)T(0.457)PK 74.987 0.018866 19135000.0 51757.0 54837.0 65440.0 65763.0 57614.0 64472.0 62378.0 56707.0 57095.0 61842.0 True False 68214.64938752241 72561.98785401818 64572.222842263574 50602.35637822166 49615.29059003024 60440.55564807425 67929.52115780202 47944.236147225085 60112.925138247316 59676.93040323984 1.143065652448824 1.2159135425316516 1.0820298967447892 0.8479383245133277 0.8313981676801634 1.0127959873216428 1.1382877889127179 0.8033964854301924 1.007305917580905 1.0 15.864885709279406 -5.550522281853952 5.564943917058508 0.9465439125064268 1.173663549181039 0.48511629915895205 0.09698497246300436 0.14309938905635516 12.714242983752579 0.027446391463995527 0.04995270391722444 2.8149955856454934e-06 5.550522281853952 0.2271196366746122 NYGSPLISGS(ph)TPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NYGSPLISGSTPK 13 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 NYGSPLIS(0.048)GS(0.476)T(0.476)PK 167.03 0.00028927 19360000.0 143670.0 174100.0 106720.0 147100.0 145000.0 124790.0 177320.0 131800.0 126890.0 114520.0 True False 167990.4933881545 191383.4974131838 109264.60953785363 138858.46390463487 116588.29089120936 118245.7927197603 160522.96591437265 128340.38965364298 128745.52619770475 135281.56946017907 1.241784036498804 1.4147048868287904 0.8076828940842257 1.026440367736188 0.8618194729440052 0.8740717097798503 1.1865841485644764 0.9486908687248837 0.9516856339813662 1.0 17.045605776725516 -5.25520350608034 24.992735381074837 0.959590422037559 1.328244487016689 0.6615670818989642 0.10616433135740393 285.428158115782 1143958.3292546552 0.026971866844119348 0.06771099997157082 5.5564382707955105e-06 5.25520350608034 0.36865406497913 NYGSPLISGS(ph)TPK ddPTM_PC-9_Lapatinib_30min_R1 1 NYGSPLISGSTPK 13 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 NYGSPLIS(0.16)GS(0.42)T(0.42)PK 144.51 9.225700000000001e-05 11443000.0 58202.0 62721.0 49161.0 52547.0 68167.0 59775.0 67546.0 63163.0 56583.0 61780.0 True False 57372.028807060386 62575.77337806674 45119.17234694785 56411.48167165334 64157.551081478356 57218.56259233076 71043.20137488363 66097.7835678682 50210.02669459501 72458.59068332463 0.7917905698414831 0.8636073761294907 0.6226890686314636 0.7785340722150657 0.8854374681654326 0.789672584751208 0.9804662318837133 0.9122145896646555 0.6929478785204992 1.0 16.144869125252995 -6.207154428908985 5.412310769072664 0.8732834608215992 0.759763529659199 0.23444150633835914 0.09974876313222619 0.3345416417799702 21.90809939889503 0.02973730003140338 0.03828249179263302 6.206483013246452e-07 6.207154428908985 -0.11351993116240022 NYGSPLISGST(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 NYGSPLISGSTPK 13 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 NYGSPLIS(0.007)GS(0.228)T(0.765)PK;NYGSPLIS(0.035)GS(0.085)T(0.88)PK 164.88 0.00019026 33950000.0 108285.0 101868.0 109996.0 122174.0 111134.0 126176.0 112410.0 114072.0 104771.0 108239.0 True False 142717.37753207973 134794.8388626864 108537.38116989039 94008.67186948367 95704.96241247644 118286.19477372235 122414.27223297513 96444.79351378581 110308.98116576414 104449.58555538741 1.3663757187088093 1.290525358678494 1.0391365422157208 0.9000387255690244 0.9162790058341219 1.1324716526615386 1.1719938531308143 0.9233621464456954 1.0560978349432475 1.0 16.67244724239594 -5.222342622011746 3.5912226505543683 1.014710325102581 1.3481924388110704 0.685296142074772 0.0850616225582142 0.13997211970501014 3.779582682635651 0.024403968130862846 0.07134312177149292 5.993180778794028e-06 5.222342622011746 0.33348211370848935 NYGSPLISGST(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NYGSPLISGSTPK 13 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 NYGSPLISGS(0.211)T(0.788)PK;NYGS(0.001)PLIS(0.047)GS(0.186)T(0.766)PK 130.19 0.0002044 29042300.0 74810.0 77229.0 70244.0 110142.0 92361.0 88328.0 99497.0 72883.0 89505.0 82976.0 True False 87473.85543514905 84895.78473131989 71918.88336185331 103971.10082518186 74263.5250689862 83695.92418744277 90071.9238641008 70969.89847592186 90813.84129817618 98018.89196234547 0.8924183255280281 0.8661165519391211 0.7337247128796495 1.0607251188385496 0.7576450170189127 0.8538754367841155 0.9189241182067479 0.7240430600173011 0.9264932451293455 1.0 16.580772217692093 -8.522646898307494 24.994128778122914 1.000000009520903 0.8519988829901567 0.2042031727340199 0.09441732572876985 30.930286609879744 3334273.419699527 0.08572582474776576 0.022134313035410236 3.0016019697162e-09 8.522646898307494 -0.14800112653074626 NYGSPLISGST(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 NYGSPLISGSTPK 13 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 NYGSPLIS(0.132)GS(0.426)T(0.442)PK 151.07 0.00032138 9090000.0 35367.0 47247.0 33800.0 35790.0 43328.0 44773.0 47025.0 41875.0 39020.0 38394.0 True False 34862.66009448651 47137.602474347004 31021.094471773078 38422.11599194007 40779.5322261255 42858.16316096064 49459.724404907836 43820.66537220331 34625.15670118404 45030.35174321079 0.7742035925744849 1.0467962307546026 0.6888930081797577 0.8532492975192661 0.9056010145928699 0.9517616785532294 1.0983641586225197 0.9731361998257128 0.7689292968137754 1.0 15.458610126520878 -6.529644405223954 2.7949564913521714 0.96512994477007 0.8457295019580039 0.19254932721002338 0.11307217681878085 0.47838729432500815 7.584469155530728 0.03965172632296055 0.042144545624304815 2.953626628629499e-07 6.529644405223954 -0.11940044281206608 NYGYNPS(ph)PVKPEGLR ddPTM_PC-9_AZD4547_30min_R2 4 NYGYNPSPVKPEGLR 15 1 E9PRF4;Q15047-3;Q15047 E9PRF4 SETDB1 Histone-lysine N-methyltransferase SETDB1 1 NYGYNPS(1)PVKPEGLR;NYGYNPS(1)PVKPEGLR;NYGYNPS(1)PVKPEGLR;NYGYNPS(1)PVKPEGLR 121.51 3.0493e-05 157174000.0 294808.0 274037.0 308452.0 402841.0 392827.0 335907.0 334828.0 317682.0 298961.0 347634.0 True False 388550.81161266455 362614.1011643896 304361.72494104365 309972.2312814077 338289.7517375947 314902.682188822 364627.0433522165 268591.5465061241 314763.46811902197 335463.4394715545 1.1582508431462368 1.080934786024983 0.9072873199550316 0.9240119631805411 1.0084250977408817 0.9387093946359066 1.0869352676005546 0.8006581788144435 0.9382944043465942 1.0 18.355796017114955 -5.077025887828435 3.7444146398348437 0.9493607625798604 1.1470391501508954 0.48929106835707725 0.07090594833476212 0.18306142212799184 4.762951251762399 0.018317505337060183 0.06310419283652327 8.374793593922724e-06 5.077025887828435 0.19767838757103506 NYGYNPS(ph)PVKPEGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NYGYNPSPVKPEGLR 15 1 E9PRF4;Q15047-3;Q15047 E9PRF4 SETDB1 Histone-lysine N-methyltransferase SETDB1 1 NY(0.001)GY(0.021)NPS(0.978)PVKPEGLR;NYGYNPS(1)PVKPEGLR;NYGYNPS(1)PVKPEGLR 131.61 4.3577e-05 83799100.0 161798.0 180390.0 160841.0 203959.0 191059.0 180470.0 178441.0 197136.0 174012.0 146304.0 True False 189187.2057438338 198297.9270440217 164676.0594328889 192531.83847399958 153622.36047850703 171005.83550072202 161537.77667903525 191961.3888828576 176556.59630163864 172827.7570581736 1.0946575305039319 1.147373144333956 0.9528334003516528 1.1140099353901447 0.8888755087343867 0.9894581658151225 0.9346749586333047 1.1107092526708175 1.0215754651158837 1.0 17.39897541505328 -5.254440448994863 24.922896106176402 1.0026477810270882 1.1210153467388784 0.33150228132817294 0.06786267403069104 596.7314187525042 2124920.8778684954 0.017212484221930426 0.04349270853340606 5.566209535902991e-06 5.254440448994863 0.11836756571179019 NYGYNPS(ph)PVKPEGLR ddPTM_PC-9_Lapatinib_30min_R1 3 NYGYNPSPVKPEGLR 15 1 E9PRF4;Q15047-3;Q15047 E9PRF4 SETDB1 Histone-lysine N-methyltransferase SETDB1 1 NYGYNPS(1)PVKPEGLR;NYGYNPS(1)PVKPEGLR;NYGYNPS(1)PVKPEGLR 110.34 0.00025337 151040000.0 265125.0 232925.0 225799.0 232692.0 236999.0 221822.0 191955.0 193888.0 209266.0 182660.0 True False 261344.268882029 232385.67647336982 207234.67782934607 249804.9459177566 223059.18477796152 212335.19015233763 201893.49065697155 202896.7443029432 185696.2594113268 214232.53762084857 1.2199093180913505 1.0847356757947242 0.967335214952794 1.166045777602021 1.0412012444754515 0.9911435140078073 0.9424034878132527 0.9470865002870498 0.8667976464899761 1.0 17.70881808757492 -6.817613034139884 1.6350825564899079 0.9322835490571273 1.0997827172259367 0.5542191343153777 0.06831034773871604 0.29766686423489946 1.6465949487093405 0.030612181673715124 0.026644223080287213 1.5219029745371276e-07 6.817613034139884 0.1674991681688094 NYGYT(ph)FGSGTR ddPTM_PC-9_AZD4547_30min_R2 1 NYGYTFGSGTR 11 0 A0A0J9YX06 A0A0J9YX06 1 NYGYT(0.991)FGS(0.006)GT(0.003)R 95.573 0.015068999999999999 65556000.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NYILDQTNVYGS(ph)AQR ddPTM_PC-9_AZD4547_30min_R2 4 NYILDQTNVYGSAQR 15 0 M0R3F1;A0A0A0MRA5;B7Z4B8;Q9BUJ2-3;Q9BUJ2-4;Q9BUJ2-2;Q9BUJ2 M0R3F1 HNRNPUL1 Heterogeneous nuclear ribonucleoprotein U-like protein 1 1 NYILDQTNVYGS(1)AQR;NYILDQTNVYGS(1)AQR;NYILDQTNVYGS(1)AQR;NYILDQTNVYGS(1)AQR 244.54 4.3740999999999995e-40 51454800.0 176316.0 174561.0 203863.0 285646.0 235049.0 208444.0 207043.0 253036.0 186769.0 220352.0 True False 232380.82039937418 230984.42952359354 201159.64341828233 219794.72788670697 202416.5035910716 195409.96372855184 225469.42590456232 213935.10038882718 196641.2280435294 212637.54354992846 1.0928494400369608 1.0862824394383446 0.9460212907841881 1.0336590811636137 0.9519321010381363 0.9189814764892095 1.0603462687745961 1.0061022000971058 0.9247719135607724 1.0 17.698036817831678 -5.247526167387539 23.90368148496949 0.9820165773045532 1.089565987989835 0.49900428467534674 0.043793475808666084 368.7226426539743 633480.6629552902 0.011201679207191562 0.029267811666013447 5.655536799622628e-06 5.247526167387539 0.10754941068528179 NYILDQTNVYGS(ph)AQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NYILDQTNVYGSAQR 15 0 M0R3F1;A0A0A0MRA5;B7Z4B8;Q9BUJ2-3;Q9BUJ2-4;Q9BUJ2-2;Q9BUJ2 M0R3F1 HNRNPUL1 Heterogeneous nuclear ribonucleoprotein U-like protein 1 1 NYILDQTNVYGS(1)AQR;NYILDQTNVYGS(1)AQR;NYILDQTNVYGS(1)AQR 223.68 3.323e-24 31703300.0 88803.0 108642.0 85984.0 106494.0 127852.0 96857.0 100031.0 104004.0 102571.0 84623.0 True False 103835.5939608009 119427.25977003516 88034.18465613609 100527.48643820632 102800.31839326154 91777.64841299632 90555.33951827545 101274.0052013468 104070.90682973266 99964.48002470042 1.0387248944339427 1.1946969537632333 0.8806546548772479 1.0056320646430292 1.0283684601556513 0.9181025939445572 0.9058751618164768 1.0130999048494305 1.0410788592509816 1.0 16.609127938482928 -5.257903049843736 24.998271470501837 0.9731969033100981 1.1167109207691936 0.4528382582816197 0.06269759113711999 261.12077568395927 1845839.6186282004 0.01603796186096927 0.03905776401548706 5.522006965886992e-06 5.257903049843736 0.14351401745909553 NYILDQTNVYGS(ph)AQR ddPTM_PC-9_Lapatinib_30min_R1 4 NYILDQTNVYGSAQR 15 0 M0R3F1;A0A0A0MRA5;B7Z4B8;Q9BUJ2-3;Q9BUJ2-4;Q9BUJ2-2;Q9BUJ2 M0R3F1 HNRNPUL1 Heterogeneous nuclear ribonucleoprotein U-like protein 1 1 NYILDQTNVYGS(1)AQR;NYILDQTNVYGS(1)AQR;NYILDQTNVYGS(1)AQR;NYILDQTNVYGS(1)AQR 233.84 8.2484e-32 42799700.0 217312.0 203249.0 229316.0 197114.0 235212.0 202426.0 214294.0 199038.0 228045.0 167358.0 True False 214213.0910298599 202778.3894280814 210462.52366535875 211610.4211130283 221377.2926045845 193768.7118580533 225389.0947714052 208286.03210394274 202360.17067969046 196285.60730948218 1.0913336640730442 1.0330782384281598 1.0722259596625643 1.0780740575613554 1.127832527504375 0.9871773815414775 1.1482711231905849 1.061137568663094 1.0309475740655327 1.0 17.582594865149765 -8.398970352684813 2.708668865240139 1.0020493879238743 1.075057739453881 0.25462154960528005 0.04250097675900699 0.3479971258013355 4.97102950433409 0.03847919968129267 0.010492757815774328 3.990521429128299e-09 8.398970352684813 0.07300835153000662 NYPS(ph)QEELIK ddPTM_PC-9_AZD4547_30min_R2 2 NYPSQEELIK 10 0 P38398-8;P38398-4;P38398;P38398-7;H0Y8B8;B7ZA85;E7EUM2;A0A2R8Y7V5;P38398-6;P38398-5;P38398-3;K7EPC7 P38398-8 BRCA1 Breast cancer type 1 susceptibility protein 1 NYPS(1)QEELIK;NYPS(1)QEELIK 130.1 0.00022435 45670000.0 63731.0 74849.0 79872.0 90782.0 100276.0 89571.0 79135.0 93239.0 75054.0 79499.0 True False 83996.1323128501 99042.47549802902 78812.84509256232 69853.6124679184 86354.40828975354 83970.11121034955 86177.86169519163 78831.0549690712 79021.20121422225 76715.76420761226 1.0949005485435213 1.2910315959311183 1.0273357230630569 0.9105509563702822 1.1256409837234584 1.0945613600759447 1.1233396758190735 1.0275730911802488 1.030051672305198 1.0 16.22723544498664 -5.282418548288341 24.95833115011602 1.0463866516058893 1.1929660819419958 0.3951246141286987 0.07439374884490318 702.96991078511 836302.9249110657 0.019784208634765904 0.04125874153796186 5.2189297582597e-06 5.282418548288341 0.14657943033610654 NYPS(ph)QEELIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NYPSQEELIK 10 0 P38398-8;P38398-4;P38398;P38398-7;H0Y8B8;B7ZA85;E7EUM2;A0A2R8Y7V5;P38398-6;P38398-5;P38398-3;K7EPC7 P38398-8 BRCA1 Breast cancer type 1 susceptibility protein 1 NYPS(1)QEELIK;NYPS(1)QEELIK;NYPS(1)QEELIK 148.89 0.00011497 27245100.0 169389.0 180249.0 179769.0 206665.0 235106.0 191587.0 197502.0 194048.0 170892.0 149327.0 True False 198063.21211474985 198142.92949585855 184055.37473772914 195086.2300669699 189038.66702254253 181539.8404503623 178793.180769346 188954.4456108514 173390.9722040988 176398.80302811813 1.122814943835976 1.1232668594937938 1.0434048960547115 1.105938513856429 1.0716550440107555 1.029144400834878 1.0135736620664384 1.0711775951264924 0.9829486891498925 1.0 17.428481245812648 -4.276437248789688 0.22552497596881074 0.9897875081642133 1.2770800034066778 0.6712122693684665 0.027564490634615812 9.081923734610406 0.3384157145824947 0.046115837538988076 0.7565636605130469 5.291304457452877e-05 4.276437248789688 0.2872924952424645 NYPS(ph)QEELIK ddPTM_PC-9_Lapatinib_30min_R1 2 NYPSQEELIK 10 0 P38398-8;P38398-4;P38398;P38398-7;H0Y8B8;B7ZA85;E7EUM2;A0A2R8Y7V5;P38398-6;P38398-5;P38398-3;K7EPC7 P38398-8 BRCA1 Breast cancer type 1 susceptibility protein 1 NYPS(1)QEELIK;NY(0.032)PS(0.968)QEELIK 95.65100000000001 0.0058347 47224000.0 117374.0 132588.0 141998.0 128147.0 143138.0 134273.0 117032.0 124367.0 136661.0 104112.0 True False 115700.22523624473 132281.00063218243 130323.47256813123 137571.35786586066 134718.9042601357 128530.45679565077 123091.34431802598 130145.54484405532 121268.79907587159 122107.6204794799 0.947526655436612 1.083314866940775 1.0672836965980514 1.1266402319991111 1.1032800715560183 1.0525997991849347 1.0080562034923233 1.065826558023266 0.9931304745738676 1.0 16.89779371313142 -7.04814721238001 5.868122237583058 1.0229244909966886 1.0708491702406777 0.18059830837167057 0.04798335992448464 0.3861896418589278 32.12074398746297 0.01867044149733868 0.014682018276643291 8.950613160548804e-08 7.04814721238001 0.04792467924398913 NYQQNYQNS(ph)ESGEK ddPTM_PC-9_AZD4547_30min_R2 4 NYQQNYQNSESGEK 14 0 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 NYQQNYQNS(0.968)ES(0.032)GEK;NYQQNYQNS(0.996)ES(0.004)GEK;NYQQNYQNS(0.98)ES(0.02)GEK;NYQQNYQNS(0.998)ES(0.002)GEK 258.96 5.0241000000000006e-45 22243300.0 56595.0 69298.0 54881.0 42383.0 51362.0 79322.0 75825.0 72429.0 72704.0 56467.0 True False 74591.03275087095 91697.2233037505 54153.24208139165 32612.254160822493 44231.272872654765 74361.98280054219 82573.27810751142 61236.76230284389 76546.98501184222 54490.10751721717 1.368891274940181 1.6828233138423714 0.993817860687482 0.5984986201489516 0.8117303284578594 1.3646877605636238 1.5153810823629013 1.1238143048900204 1.4047868227761482 1.0 15.733706717122047 -5.265469299160244 24.977712115213365 1.1018665108276853 1.5258573033078298 0.2798325107976708 0.2722495167123439 450.8571411851088 2794461.631710372 0.07989365402982847 0.1766953186348142 5.42663611567106e-06 5.265469299160244 0.4239907924801445 NYQQNYQNS(ph)ESGEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NYQQNYQNSESGEK 14 0 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 NYQQNYQNS(0.999)ES(0.001)GEK;NYQQNYQNS(0.972)ES(0.028)GEK;NYQQNYQNS(0.997)ES(0.003)GEK 230.96 1.1256999999999997e-89 14903500.0 35556.0 65129.0 36579.2 34868.9 40342.0 27714.8 36773.7 28098.4 27746.0 26325.5 True False 41574.92853698911 71594.57669743412 37451.386855388526 32915.308579499084 32437.27469747013 26261.387098883 33290.22891746764 27360.846772715704 28151.73275972505 31098.10475745665 1.3368958932142108 2.30221671885864 1.2042980479834062 1.0584345520801137 1.0430627509444084 0.8444690537800728 1.0704906031125696 0.8798236093842717 0.9052555768040776 1.0 14.92453903899423 -5.454226490779343 5.703779705048959 0.9787641920500918 1.8181460739345716 0.6821271474762095 0.22820176886480703 0.10809304447349702 6.584978398274788 0.05584487692543004 0.11705232388294835 3.513771445338799e-06 5.454226490779343 0.8393818818844798 NYQQNYQNS(ph)ESGEK ddPTM_PC-9_Lapatinib_30min_R1 3 NYQQNYQNSESGEK 14 0 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 NYQQNYQNS(0.97)ES(0.03)GEK;NYQQNYQNS(0.989)ES(0.011)GEK;NYQQNYQNS(0.998)ES(0.002)GEK 200.0 5.1409e-08 25146000.0 68333.0 90167.0 68322.0 67094.0 81588.0 72742.0 73825.0 84686.0 67138.0 64907.0 True False 67358.55888926252 89958.22385134416 62704.828890546705 72028.3165790229 76789.1542481796 69630.99422988415 77647.2972715008 88620.82072144271 59576.21144551757 76126.08846685899 0.8848288444320458 1.1817003298482478 0.8236969763374202 0.946171253897801 1.008710099187735 0.9146797849753907 1.0199827527629253 1.1641320670248705 0.782599141048127 1.0 16.216103330673683 -7.313576968160108 24.97797517303881 1.0053561687379384 0.9654380319511973 0.009601994858787433 0.1237945642427688 1793.605910008395 859270.1435699301 0.04991689702381384 0.03365403391590526 4.857614338797508e-08 7.313576968160108 -0.039918136786741165 NYQQNYQNS(ph)ESGEKNEGSESAPEGQAQQR ddPTM_PC-9_AZD4547_30min_R2 3 NYQQNYQNSESGEKNEGSESAPEGQAQQR 29 1 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 NYQQNY(0.01)QNS(0.817)ES(0.173)GEKNEGSESAPEGQAQQR;NYQQNY(0.041)QNS(0.776)ES(0.164)GEKNEGS(0.014)ES(0.004)APEGQAQQR;NY(0.001)QQNY(0.187)QNS(0.663)ES(0.143)GEKNEGS(0.004)ES(0.002)APEGQAQQR 96.31700000000001 6.7637e-06 141294900.0 14210.2 14430.7 18910.9 26547.6 22260.0 25716.6 21183.4 17792.5 17754.199999999997 23540.9 True False 18728.74800947834 19095.141567280876 18660.129109837446 20427.460976331335 19169.58323556901 24108.536936643293 23068.68156231658 15043.077955975496 18692.650766082334 22716.74025629231 0.8244469848305223 0.8405757759188938 0.8214263533989555 0.899225009656618 0.8438527279572706 1.0612674470301904 1.015492597179597 0.6622023136355892 0.822857969725857 1.0 14.471468209397267 -5.76416618761102 24.59811823741857 0.8957295603061105 0.8299923055644007 0.08467653327895253 0.10741652902852418 181.8019447764806 1640040.4560682313 0.03241847565731092 0.050638581001341276 1.7212098088860074e-06 5.76416618761102 -0.06573725474170977 NYQQNYQNS(ph)ESGEKNEGSESAPEGQAQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NYQQNYQNSESGEKNEGSESAPEGQAQQR 29 1 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 NYQQNY(0.032)QNS(0.778)ES(0.141)GEKNEGS(0.039)ES(0.011)APEGQAQQR;NY(0.001)QQNY(0.249)QNS(0.582)ES(0.164)GEKNEGS(0.003)ES(0.001)APEGQAQQR;NYQQNY(0.028)QNS(0.486)ES(0.337)GEKNEGS(0.108)ES(0.041)APEGQAQQR 107.88 9.6001e-12 222039000.0 20164.6 21876.8 16829.4 26440.0 26499.3 22928.9 22838.2 25454.9 21630.5 16252.4 True False 23578.068510995916 24048.584125265603 17230.67672185493 24958.652519636566 21306.952391816718 21726.468119978428 20674.800361750637 24786.735846695923 21946.805141614386 19198.83146607239 1.2280991451309098 1.2526066582626942 0.8974857012680418 1.300008938759776 1.109804647718781 1.1316557551105546 1.0768780588697042 1.2910544003940194 1.1431323401321654 1.0 14.228730883756008 -12.000615235953667 1.680798039988114 6.12653055370046e-05 1.1574022230786685 0.14933363479513484 0.11376919759974952 1553495.7280110768 119941.06034580668 5880416.627335708 0.028730813138972373 9.985843698154721e-13 12.000615235953667 1.1573409577731315 NYQQNYQNS(ph)ESGEKNEGSESAPEGQAQQR ddPTM_PC-9_Lapatinib_30min_R1 6 NYQQNYQNSESGEKNEGSESAPEGQAQQR 29 1 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 NY(0.002)QQNY(0.201)QNS(0.257)ES(0.257)GEKNEGS(0.221)ES(0.063)APEGQAQQR;NYQQNY(0.032)QNS(0.824)ES(0.142)GEKNEGS(0.001)ESAPEGQAQQR;NYQQNY(0.027)QNS(0.86)ES(0.105)GEKNEGS(0.007)ES(0.002)APEGQAQQR;NYQQNY(0.124)QNS(0.428)ES(0.428)GEKNEGS(0.014)ES(0.006)APEGQAQQR;NYQQNY(0.036)QNS(0.48)ES(0.48)GEKNEGS(0.004)ES(0.001)APEGQAQQR;NYQQNY(0.009)QNS(0.831)ES(0.136)GEKNEGS(0.018)ES(0.006)APEGQAQQR 110.83 7.5672e-11 385098600.0 60854.5 49412.299999999996 52112.299999999996 50328.4 55948.8 55676.8 48750.8 47482.299999999996 54475.399999999994 39688.299999999996 True False 59986.703670651485 49297.888855232646 47827.827853295305 54029.71842662075 52658.00158357301 53295.63305295995 51274.87788450362 49688.501000658325 48339.80680060688 46548.36977366444 1.2886961232440415 1.059067999479625 1.027486635640562 1.1607220336465793 1.1312534002719297 1.1449516559248631 1.1015397130731157 1.0674595317142657 1.0384854944577668 1.0 15.506443021863399 -7.293708801908196 0.017511208558254013 1.3625482032354213e-05 2.186220233523294 0.3551886734503401 0.06425570265334779 671.1581322665444 7.258979458519936 440.35989515068997 463.96081723629544 5.085002819829402e-08 7.293708801908196 2.1862066080412617 NYQQNYQNSES(ph)GEK ddPTM_PC-9_Lapatinib_30min_R1 1 NYQQNYQNSESGEK 14 0 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 NYQQNYQNS(0.049)ES(0.951)GEK 264.85 2.5186e-56 7836800.0 20925.0 20828.0 15635.0 19208.0 22573.0 21411.0 24925.0 24797.0 20622.0 17736.0 True False 20626.605662824968 20779.774045668502 14349.550652845332 20620.620396009628 21245.300520225523 20495.301441478776 26215.49454103836 25949.159145899117 18299.333200712907 20801.643968265515 0.9915853619210299 0.9989486445095216 0.6898277210559252 0.9912976314500886 1.0213279562248465 0.9852731578689604 1.2602607073283287 1.2474571329788418 0.8797061053746487 1.0 14.3444099296053 -6.569341507536185 1.6735789692263419 1.1084851126012152 0.9071979629194719 0.22813852643174237 0.1361156169519988 0.4915909708251991 2.812741784545137 0.055300511517843355 0.058438566670213014 2.695618898455669e-07 6.569341507536185 -0.20128714968174333 NYQQNYQNSES(ph)GEKNEGSESAPEGQAQQR ddPTM_PC-9_AZD4547_30min_R2 2 NYQQNYQNSESGEKNEGSESAPEGQAQQR 29 1 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 NYQQNY(0.011)QNS(0.124)ES(0.639)GEKNEGS(0.177)ES(0.05)APEGQAQQR;NYQQNY(0.037)QNS(0.127)ES(0.406)GEKNEGS(0.326)ES(0.103)APEGQAQQR 73.654 7.0109e-06 123644500.0 8478.8 5794.759999999999 7583.299999999999 10499.7 10588.400000000001 8868.3 7072.0 9933.3 8293.6 8127.299999999999 True False 11174.882030004152 7667.802847291997 7482.740487159805 8079.15638374792 9118.383429087999 8313.763799072733 7701.394299720671 8398.336729526003 8731.982764280023 7842.76570075759 1.4248649591718248 0.9776911793439536 0.9540946105832273 1.030141239966852 1.162648965556524 1.060055102534766 0.981974292433183 1.0708386620187758 1.1133805467931468 1.0 12.937146785832914 -4.7556554263922575 24.999099477734788 1.0410070753052072 1.424865576598594 0.7784334688675444 0.06175326135535313 93.25005011326293 402999.6956196492 0.016533880059665284 0.14401695866622843 1.755272600442514e-05 4.7556554263922575 0.38385850129338683 NYQQNYQNSES(ph)GEKNEGSESAPEGQAQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NYQQNYQNSESGEKNEGSESAPEGQAQQR 29 1 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 NYQQNY(0.014)QNS(0.156)ES(0.404)GEKNEGS(0.269)ES(0.156)APEGQAQQR 82.831 3.5693000000000006e-07 12897000.0 15701.0 14305.0 10887.0 17500.0 21453.0 17357.0 20522.0 20136.0 16806.0 16799.0 True False 18358.86919111448 15725.105861548524 11146.587369177425 16519.531735765508 17249.438651649056 16446.768364747793 18578.007593586473 19607.451335855556 17051.755956171688 19844.525719189176 0.9251351960184112 0.792415303044644 0.5616958312286066 0.832447797923007 0.8692290708146916 0.8287811257108637 0.9361779594269662 0.9880534114703293 0.8592674976194091 1.0 14.276453462131572 -6.831082770163509 1.192096531406259 0.9473377830329173 0.7674196780550977 0.3680755139936268 0.09453107120369596 0.5215629847781188 1.5575488498616967 0.05224195942369982 0.04408260103163501 1.4754253120368356e-07 6.831082770163509 -0.17991810497781957 NYQQNYQNSES(ph)GEKNEGSESAPEGQAQQR ddPTM_PC-9_Lapatinib_30min_R1 3 NYQQNYQNSESGEKNEGSESAPEGQAQQR 29 1 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 NYQQNY(0.009)QNS(0.235)ES(0.634)GEKNEGS(0.088)ES(0.033)APEGQAQQR;NYQQNYQNS(0.023)ES(0.903)GEKNEGS(0.05)ES(0.024)APEGQAQQR;NYQQNY(0.005)QNS(0.054)ES(0.516)GEKNEGS(0.189)ES(0.236)APEGQAQQR 98.37700000000001 4.9329e-11 42483800.0 53208.6 48731.5 50349.8 44499.0 58272.2 44129.3 46985.1 46854.2 45887.4 39916.3 True False 52449.83560673782 48618.66520580441 46210.23379984855 47771.60490431238 54844.74376355317 42241.99270942268 49417.75857814006 49031.21718166656 40719.07779625609 46815.779269873536 1.1203452430939211 1.0385102195039408 0.9870653553253004 1.0204167408797984 1.1715012463510643 0.9023024580220085 1.0555791091987852 1.0473224614936332 0.8697725089980348 1.0 15.51470725204071 -8.239348378160726 24.338678832178267 0.9348862517986072 1.0401501300019984 0.2538784236610383 0.0739361489933876 678.8504809679259 747924.057241752 0.04837591358988951 0.018247976479936506 5.763039839493498e-09 8.239348378160726 0.10526387820339123 NYQQNYQNSESGEKNEGS(ph)ESAPEGQAQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NYQQNYQNSESGEKNEGSESAPEGQAQQR 29 1 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 NYQQNY(0.005)QNS(0.063)ES(0.186)GEKNEGS(0.559)ES(0.186)APEGQAQQR;NYQQNY(0.01)QNS(0.042)ES(0.161)GEKNEGS(0.626)ES(0.161)APEGQAQQR 87.881 1.8372e-08 40996000.0 13542.099999999999 12216.6 9969.5 13343.900000000001 15132.6 13799.3 12296.0 14670.0 13501.5 12463.8 True False 15834.510061333121 13429.383311303289 10207.210689539299 12596.284544507507 12167.475660278038 13075.6404157207 11131.233864669104 14284.928044149832 13698.933895171484 14723.388276613483 1.0754664458917065 0.9121122841428028 0.6932650622107381 0.8555289249904079 0.8264045905523502 0.888086367761553 0.7560239297872672 0.9702201542045795 0.9304199303723291 1.0 13.845822094922676 -7.802452333315952 24.965020392053606 0.9627403037646951 0.8536945535295112 0.21077622334161772 0.09606890276625622 252.8708285136941 153921.91951005123 0.053925806083627036 0.025905524636757066 1.57596898624333e-08 7.802452333315952 -0.10904575023518392 NYQQNYQNSESGEKNEGS(ph)ESAPEGQAQQR ddPTM_PC-9_Lapatinib_30min_R1 2 NYQQNYQNSESGEKNEGSESAPEGQAQQR 29 1 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 NYQQNY(0.002)QNS(0.008)ES(0.008)GEKNEGS(0.73)ES(0.251)APEGQAQQR;NYQQNYQNSES(0.001)GEKNEGS(0.777)ES(0.221)APEGQAQQR 95.51899999999999 6.6848e-11 48812000.0 19746.6 21904.8 19955.4 17415.2 20111.9 21564.4 14116.9 15294.8 17741.4 16403.7 True False 19465.009862917064 21854.080781426892 18314.744042071623 18695.97190340416 18928.95758351675 20642.140881071624 14847.8040074778 16005.452244412536 15743.176706775672 19239.057688443678 1.0117444512165017 1.1359226182139877 0.9519563971718188 0.9717717055671737 0.9838817415099703 1.0729288936781314 0.7717531829220736 0.8319249572200477 0.8182925048471643 1.0 14.231750518496204 -7.258255156792721 24.999914408971097 0.8414864057448386 1.0194613605112635 0.5416478589804757 0.07429492433927444 203.90191473769363 1600878.01497955 0.028813509894581413 0.021364048961429804 5.517531778825388e-08 7.258255156792721 0.1779749547664249 NYQQNYQNSESGEKNEGSES(ph)APEGQAQQR ddPTM_PC-9_Lapatinib_30min_R1 1 NYQQNYQNSESGEKNEGSESAPEGQAQQR 29 1 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 NYQQNYQNS(0.074)ES(0.29)GEKNEGS(0.191)ES(0.445)APEGQAQQR 86.508 2.0162e-08 9154800.0 30171.0 26460.0 20849.0 23186.0 25533.0 25199.0 19016.0 23723.0 24494.0 19530.0 True False 29740.756007316246 26398.733495697557 19134.87569946736 24891.175786228607 24031.199139809418 24121.297511738056 20000.555433997408 24825.25718506933 21735.227786745298 22905.73447791078 1.298397832909346 1.1524945214551081 0.8353749022071368 1.0866787882411058 1.049134624475106 1.0530680662084644 0.8731680467738333 1.0838009673520685 0.9488989670995154 1.0 14.483421203512147 -5.012297743562401 5.4808900607689015 0.9969129066701282 1.2702120163874242 0.5944334775782001 0.08139212302472253 0.09738748435189588 10.242768705196239 0.019989861758666315 0.06697409252324152 9.720805563969107e-06 5.012297743562401 0.273299109717296 NYQQNYQNSESGEKNEGSESAPEGQAQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NYQQNYQNSESGEKNEGSESAPEGQAQQR 29 1 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 153.57 1.3944999999999999e-22 0.0 3139.1 1667.3 3275.4 3778.8 3436.7 4620.3 4833.8 3795.3 2982.2 2958.0 False True 3670.487629948883 1832.818525198172 3353.4979580236736 3567.0860870348965 2763.3033055573724 4378.003334426699 4375.907470318602 3695.6773964527483 3025.8090332318925 3494.261984484884 1.0504328657228539 0.5245223550312476 0.9597156632541501 1.0208410539545585 0.7908117129817134 1.2529121610989036 1.252312359447681 1.057641760366619 0.8659365115343377 1.0 11.770772063937866 -5.506593540280156 21.850215324392906 1.0406001945953423 0.7761378106729148 0.22621529781362393 0.17991037462606502 178.71372342622524 239780.5697459738 0.04802503089390828 0.09533384661722694 3.1146299808440456e-06 5.506593540280156 -0.2644623839224275 NYQQNYQNSESGEKNEGSESAPEGQAQQR ddPTM_PC-9_Lapatinib_30min_R1 1 NYQQNYQNSESGEKNEGSESAPEGQAQQR 29 1 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 65.775 0.00026507 5906800.0 2889.6 1322.1 3813.4 2280.6 2087.3 3381.2 2380.3 2778.3 2740.1 2138.7 False True 2848.3937741122595 1319.0387586795812 3499.8769721496883 2448.3229318585777 1964.5291177896922 3236.593957962168 2503.540287102653 2907.389960682805 2431.481083467821 2508.3714453613816 1.1355550149399387 0.5258546381234008 1.3952785894696151 0.9760607570247026 0.7831890772886159 1.290316856360112 0.998073986104545 1.159074731957785 0.9693465008797838 1.0 11.292535286191802 -6.755251096446496 24.999958236618376 1.087974054685767 0.963611618228962 0.06519783775719445 0.22718523949755087 457.6613227389286 1848898.235793181 0.0738206967278402 0.07204025041968756 1.756907527384014e-07 6.755251096446496 -0.124362436456805 NYQSQADIPIRS(ph)PFGIVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NYQSQADIPIRSPFGIVK 18 1 Q14966-3;Q14966;Q14966-2;Q14966-6;Q14966-4 Q14966-3 ZNF638 Zinc finger protein 638 1 NYQSQADIPIRS(1)PFGIVK 68.329 0.0057067 8008100.0 25682.0 26185.0 21255.0 30228.0 36660.0 38784.0 43249.0 33685.0 31407.0 32397.0 True False 30029.455357378618 28784.473749363708 21761.799810036387 28534.42316049827 29476.736166011964 36750.098764670096 39152.14162435542 32800.80444220768 31866.267958793516 38270.319645489086 0.7846669595538166 0.7521357024452375 0.5686338659207265 0.7456019031150585 0.7702244569437867 0.9602767655221772 1.0230419287592827 0.8570820611390922 0.8326627071313105 1.0 15.223938330439216 -6.620644916132912 3.539449168584166 0.9310976749993136 0.7091905728162046 0.6579234606925372 0.07648227726230299 0.15850868129548165 3.8824368100957356 0.028142261751864003 0.028204503869654587 2.395273357430229e-07 6.620644916132912 -0.22190710218310905 NYS(ph)VGSR ddPTM_PC-9_AZD4547_30min_R2 1 NYSVGSR 7 0 O60825 O60825 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2;6-phosphofructo-2-kinase;Fructose-2,6-bisphosphatase 1 NYS(0.975)VGS(0.025)R 77.533 0.029654000000000003 8007700.0 17628.0 19456.0 26717.0 23380.0 19094.0 27516.0 23705.0 28910.0 24180.0 25088.0 True False 23233.337314822056 25744.771517183286 26362.715123422324 17990.1022173992 16443.127686431028 25795.420170188783 25814.699077330093 24442.623785710348 25458.10543555162 24209.676756192875 0.9596715209705942 1.0634083129836804 1.088932966305661 0.7430955150112568 0.679196498657292 1.0655003959765912 1.0662967266065067 1.009622062775286 1.05156734193237 1.0 14.563296196376973 NYS(ph)VGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 NYSVGSR 7 0 O60825 O60825 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2;6-phosphofructo-2-kinase;Fructose-2,6-bisphosphatase 1 NYS(0.981)VGS(0.019)R;NYS(0.974)VGS(0.026)R 76.282 0.031484 9856300.0 27128.0 48514.0 34110.0 39988.0 42762.0 31915.0 47214.0 47027.0 43409.0 37698.0 True False 31720.23459757679 53330.14930214367 34923.31176289536 37747.60200284521 34383.09306958548 30241.321216853466 42741.54812024131 45792.59107922519 44043.774503240274 44532.34898279621 0.7122964613843071 1.197559763190265 0.7842234366839032 0.8476445295402654 0.7720925092648581 0.6790865945233728 0.9597865169150019 1.0282994749932421 0.9890287736731632 1.0 15.442566092306059 -7.504920853333395 23.5970152107793 1.0040071342830754 0.8424626195700464 0.263523493631059 0.13376474459740964 537.3697464405533 706119.1650568587 0.05835060886377583 0.03837642368472319 3.126649121790815e-08 7.504920853333395 -0.161544514713029 NYS(ph)VGSR ddPTM_PC-9_Lapatinib_30min_R1 1 NYSVGSR 7 0 O60825 O60825 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2;6-phosphofructo-2-kinase;Fructose-2,6-bisphosphatase 1 NYS(1)VGSR 84.81700000000001 0.019701 5226300.0 7062.1 14112.0 11709.0 11178.0 17261.0 19635.0 21894.0 21408.0 18500.0 18005.0 True False 6961.393158969475 14079.324531038703 10746.331218047075 12000.067408714895 16245.741916431683 18795.256821420553 23027.564191835263 22402.69383374634 16416.335186363518 21117.140259845553 0.3296560553801232 0.6667249617037717 0.5088914069714888 0.5682619550305843 0.7693154336490874 0.8900474491406356 1.0904679283502416 1.0608772569619798 0.7773938603599342 1.0 14.366126853815636 -6.498152789204405 1.6267823895253384 0.9869989040882624 0.5137590465710272 0.7868551810381377 0.11002750545035699 0.16797233829514968 0.9006663612604611 0.04255893960121788 0.04761421516877002 3.1757566107025265e-07 6.498152789204405 -0.4732398575172352 NYSS(ph)PPPCHLSR ddPTM_PC-9_AZD4547_30min_R2 1 NYSSPPPCHLSR 12 0 Q12986-3;Q12986-2;Q12986 Q12986-3 NFX1 Transcriptional repressor NF-X1 1 NY(0.026)S(0.12)S(0.854)PPPCHLSR 57.328 0.041298 4758600.0 3842.1 8325.1 13890.0 48587.0 30581.0 19843.0 9169.5 26253.0 12138.0 18691.0 True False 5063.807879355447 11016.025768796388 13705.80952443523 37386.017811666985 26335.356016484075 18602.214073159477 9985.567736324756 22196.202083924367 12779.589899781879 18036.633779097632 0.2807512721816093 0.6107584100067877 0.7598873322093325 2.0727824420870067 1.4601037166371753 1.0313573087411292 0.5536270159178411 1.230617772460801 0.7085351987681838 1.0 14.138642489575233 -5.53095449694481 24.999494569072173 1.1645940724520092 0.5056466137473319 0.3367946949767696 0.40052856105564044 217.7404777607413 674040.6304803126 0.11754131617738874 0.20403903279299718 2.944730150726323e-06 5.53095449694481 -0.6589474587046773 NYTNS(ph)PEESSK ddPTM_PC-9_AZD4547_30min_R2 3 NYTNSPEESSK 11 0 J3QQU0;A0A3B3ITH3;Q9P2X3-2;Q9P2X3 J3QQU0 IMPACT Protein IMPACT 1 NYT(0.011)NS(0.989)PEESSK;NYT(0.006)NS(0.978)PEESS(0.015)K;NYT(0.244)NS(0.755)PEES(0.001)SK 138.55 5.3911000000000006e-05 14225500.0 89956.0 88027.0 119165.0 150202.0 136545.0 121239.0 103395.0 120735.0 99325.0 120949.0 True False 118560.1367989639 116480.00628819369 117584.79423897232 115575.24949776696 117588.0836882644 113657.906164178 112596.95469734412 102078.17996429408 104575.11672399373 116714.61232401055 1.0158122829541685 0.9979899171907834 1.0074556381384883 0.9902380447181659 1.0074838218356843 0.9738104244278613 0.96472029041886 0.8745964016991773 0.8959899248406321 1.0 16.832625667938657 -7.375721113688604 2.2631803263159913 0.9152526349608252 1.0010819514732432 0.5035483340393508 0.03270294357683684 0.22029827983660302 2.203105046955541 0.016135222489678677 0.009630802921327472 4.20996888736141e-08 7.375721113688604 0.08582931651241799 NYTNS(ph)PEESSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 NYTNSPEESSK 11 0 J3QQU0;A0A3B3ITH3;Q9P2X3-2;Q9P2X3 J3QQU0 IMPACT Protein IMPACT 1 NYT(0.006)NS(0.956)PEES(0.032)S(0.006)K;NYT(0.004)NS(0.969)PEES(0.019)S(0.007)K;NY(0.002)T(0.005)NS(0.992)PEES(0.002)S(0.001)K 86.738 0.028088 11965700.0 63048.0 66806.0 66558.0 84872.0 93171.0 77762.0 84185.0 80091.0 66996.0 63073.0 True False 73720.78114523833 73438.0581745272 68144.99514262074 80116.89699873666 74914.81138361983 73684.02382782272 76210.38735338056 77988.69611342894 67975.68975602038 74507.63561440664 0.989439277428686 0.985644727133542 0.9146041822516828 1.0752843831115402 1.0054648864623812 0.9889459411804947 1.0228533857628503 1.0467208557930567 0.9123318596205292 1.0 16.185100661480774 -5.748720039081527 24.99998296420189 1.0091162186722071 0.965470962892485 0.17275249450907926 0.044068625671724516 411.72732806811626 809246.4695900853 0.011681607477536759 0.020065357823031527 1.7835281195286424e-06 5.748720039081527 -0.043645255779722114 NYTNS(ph)PEESSK ddPTM_PC-9_Lapatinib_30min_R1 3 NYTNSPEESSK 11 0 J3QQU0;A0A3B3ITH3;Q9P2X3-2;Q9P2X3 J3QQU0 IMPACT Protein IMPACT 1 NYT(0.006)NS(0.988)PEES(0.005)S(0.001)K;NYT(0.005)NS(0.995)PEESSK;NYT(0.002)NS(0.748)PEES(0.037)S(0.213)K 155.39 1.1476e-11 13853800.0 76642.0 74526.0 74379.0 61483.0 76455.0 75343.0 68007.0 72373.0 69743.0 52739.0 True False 75549.07102557858 74353.4396258637 68263.84573124295 66004.66492127543 71958.0672163133 72120.75552311128 71528.06969919345 75735.71379062608 61887.80891365144 61854.8658796998 1.2213925283180203 1.2020629027063465 1.1036131880717006 1.0670892901076932 1.1633372119222278 1.1659673737451373 1.1563854950119343 1.2244099589177486 1.0005325859733607 1.0 15.9165994703758 -8.276915939906162 24.676592325547173 1.000266223494812 1.1590409756000866 0.6616337498583167 0.04648944764895003 512.2375730744991 816727.2937394007 0.04774215869459027 0.012521242000954795 5.285475451695496e-09 8.276915939906162 0.15877475210527447 NYYEQWGK ddPTM_PC-9_AZD4547_30min_R2 2 NYYEQWGK 8 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ; 118.26 0.016175 63737000.0 177394.0 167864.0 228250.0 320580.0 257030.0 234780.0 203090.0 252640.0 174336.0 240800.0 False True 233801.60197558152 222122.75524056627 225223.25586409934 246675.23391162677 221345.82116075064 220099.16948527817 221164.61656253887 213600.29308965305 183551.04504600214 232369.6652938151 1.0061623219190674 0.955902548466073 0.9692455148107235 1.061563838807115 0.9525590221979896 0.9471940720273373 0.9517792104356296 0.91922623729552 0.7899096674857053 1.0 17.82606221879619 -7.3204482453314075 1.2969119069628035 0.8935664631018095 0.989623257010533 0.29163698647167324 0.05634155782640708 0.544434726698522 1.7706158301804635 0.036282631423280184 0.019930316031325696 4.781363420365449e-08 7.3204482453314075 0.09605679390872346 NYYEQWGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 NYYEQWGK 8 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 99.44200000000001 0.023951 3042400.0 11775.0 11295.0 13316.0 14506.0 13904.0 12960.0 14430.0 14534.0 16244.0 11016.0 False True 13768.274933149027 12416.292953945504 13633.503941211218 13693.27584908653 11179.61101069914 12280.354785223919 13063.08593584703 14152.497900045906 16481.537769371214 13013.113597391974 1.0580307956359036 0.9541369835143773 1.047674243306658 1.0522674490316346 0.8591034672086244 0.943690738831719 1.0038401523264249 1.0875566246407227 1.2665329973507928 1.0 13.667678570973761 -7.84498262904011 3.565951072186276 1.1445081006543874 0.9843077668567953 0.34335961931768577 0.08294554613521529 0.23709716156052837 5.830881395571375 0.04977819255457893 0.022223229668971587 1.4289511127165638e-08 7.84498262904011 -0.16020033379759202 NYYEQWGK ddPTM_PC-9_Lapatinib_30min_R1 2 NYYEQWGK 8 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ; 131.06 0.016175 89673000.0 333390.0 315910.0 284250.0 290090.0 318900.0 277900.0 287450.0 281570.0 287160.0 265760.0 False True 328635.797463761 315178.5298044527 260880.06223673114 311424.1863118719 300142.92898152274 266014.86481654044 302332.75449634786 294652.77012182213 254817.01687114325 311696.2618970597 1.0543462904033662 1.011171991239802 0.8369688511788729 0.9991271130955122 0.9629340023354129 0.8534425892614461 0.9699595133296651 0.9453201919345882 0.8175170767857932 1.0 18.249781327587733 -5.0458110173903945 9.184517917948746 0.9244121435780663 1.043784999639383 0.33635409669463734 0.06285980887664268 0.4067037386531872 80.0824898283032 0.01535900232432721 0.04150471980220386 8.998890817633129e-06 5.0458110173903945 0.11937285606131676 PAAAAAAGSAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 PAAAAAAGSASPR 13 0 Q96S55-2;Q96S55 Q96S55-2 WRNIP1 ATPase WRNIP1 1 PAAAAAAGS(0.038)AS(0.962)PR 81.565 0.011492 2519900.0 8172.7 8856.0 11747.0 12265.0 11945.0 10458.0 11340.0 13975.0 9771.3 8393.1 True False 10771.44859727968 11718.528811481045 11591.22710464655 9437.493742361043 10286.642935708529 9804.059606768222 12349.23803150911 11815.484863552472 10287.79096949568 8099.260123660815 1.329929948269281 1.4468641125930823 1.4311464167923758 1.1652291194834912 1.2700719298615428 1.210488298570271 1.5247365614832644 1.4588350890268662 1.2702136753752837 1.0 12.983574406896542 -8.54759172825637 20.83040128300097 0.9999999953486841 1.352796570236907 0.4892617513876262 0.10890104239954923 598.5407280847976 504506.48135219264 0.11366470216062897 0.0293480999141454 2.8340549835216847e-09 8.54759172825637 0.3527965748882228 PAAMISQPPT(ph)PPTGQPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PAAMISQPPTPPTGQPVR 18 0 Q6PKG0;Q6PKG0-3 Q6PKG0 LARP1 La-related protein 1 1 PAAMIS(0.008)QPPT(0.496)PPT(0.496)GQPVR 79.347 0.029661 0.0 11841.0 22614.0 14239.0 11592.0 15131.0 11616.0 16335.0 9690.2 10174.0 10636.0 True False 13845.447429589614 24858.968469280542 14578.511761708212 10942.537821771071 12166.189168792334 11006.836511200692 14787.630544841388 9435.842517615592 10322.77550268301 12564.222605470328 1.1019740627296315 1.978552056094359 1.1603194419176308 0.8709283626514869 0.9683200903727467 0.876045964547654 1.1769634309410446 0.7510088617426539 0.8216008126271643 1.0 13.617033788696466 -5.494742881454298 7.4776643620317795 0.9299198409695801 1.5498064367610975 0.5444123020723232 0.22406934441072296 0.14196073765342773 30.266052175499592 0.05527427358643539 0.11089042528883142 3.2007895357427197e-06 5.494742881454298 0.6198865957915174 PAAMISQPPT(ph)PPTGQPVR ddPTM_PC-9_Lapatinib_30min_R1 1 PAAMISQPPTPPTGQPVR 18 0 Q6PKG0;Q6PKG0-3 Q6PKG0 LARP1 La-related protein 1 1 PAAMIS(0.021)QPPT(0.733)PPT(0.245)GQPVR 88.95100000000001 0.0090241 0.0 6331.8 13749.0 12146.0 12058.0 10364.0 11844.0 11342.0 12323.0 11261.0 13373.0 True False 6241.50737089009 13717.165035236036 11147.402764915858 12944.785544308828 9754.409896407971 11337.459729712506 11929.23326316779 12895.571567323248 9992.667596412955 15684.505231597592 0.3979409792484951 0.8745679148107137 0.7107270902277869 0.8253231678759368 0.6219137774749179 0.722844588484204 0.7605744068442446 0.8221854229321922 0.6371044192252867 1.0 13.937052399570694 -14.522878745280336 0.21011847681639254 2.3170723949954333 0.6808977449399589 0.3222098016564957 0.12827905091539157 179.6157352196192 1.785627143814956 100.02122455124321 0.2589521030829317 3.0000000000000132e-15 14.522878745280336 -1.6361746500554744 PAAMISQPPT(ph)PPTGQPVREDAK ddPTM_PC-9_AZD4547_30min_R2 1 PAAMISQPPTPPTGQPVREDAK 22 1 Q6PKG0;Q6PKG0-3 Q6PKG0 LARP1 La-related protein 1 1 PAAMIS(0.011)QPPT(0.84)PPT(0.148)GQPVREDAK 79.762 0.00035628 12245000.0 106040.0 87704.0 83889.0 83566.0 74340.0 90438.0 100280.0 97808.0 92518.0 95249.0 True False 139758.51423098097 116052.6028548029 82776.5770479011 64301.14978182987 64019.17420180602 84782.89756329152 109204.72573189909 82694.0210042462 97408.31260075944 91914.36150153943 1.5205296751002315 1.2626166461794894 0.9005837139663393 0.6995767443888833 0.6965089367534124 0.9224118644600663 1.1881138480200406 0.8996855295879 1.05977249919892 1.0 16.48800267793304 -5.055446472544555 2.773953853484953 0.9107225264042954 1.510249327071921 0.6565836402666949 0.1417340525302963 0.19185624088840705 2.7041345826297785 0.04199934641655927 0.1949629704717068 8.801435840379015e-06 5.055446472544555 0.5995268006676256 PAAS(ph)PRPR ddPTM_PC-9_AZD4547_30min_R2 2 PAASPRPR 8 1 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;F8W7E0;E9PSG1 P20810-6 CAST Calpastatin 1 PAAS(1)PRPR;PAAS(1)PRPR 79.48899999999999 0.0097387 5731800.0 11809.3 15572.8 12499.2 13009.9 12525.6 13505.8 15779.400000000001 15361.099999999999 17983.7 18376.2 True False 15564.411751300653 20606.403057298114 12333.4524411678 10010.668555951313 10786.636647594029 12661.280190962925 17183.736031251745 12987.394957961784 18934.281667548785 17732.854831279958 0.8777160755777311 1.1620465657311616 0.6955142056095865 0.5645266174678735 0.6082853973725024 0.7140012316927671 0.969033818567127 0.7323916583951617 1.0677514617753237 1.0 14.11413719550288 -8.264790132597577 24.676380973404132 1.0338757672359085 0.7894651495586053 0.2513810184663746 0.1680320213595246 396.2038285189559 2917727.401543761 0.15595194261479575 0.04676582797566873 5.435129138926515e-09 8.264790132597577 -0.2444106176773032 PAAS(ph)PRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PAASPRPR 8 1 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;F8W7E0;E9PSG1 P20810-6 CAST Calpastatin 1 PAAS(1)PRPR;PAAS(1)PRPR 75.652 0.0123 5367120.0 8301.810000000001 19247.3 11307.0 11896.21 19030.4 11715.0 10799.7 7399.9 9980.7 12197.26 True False 9707.142464778428 21158.044743025723 11576.601762036289 11229.703921733195 15301.529730869453 11100.644776921148 9776.674232942989 7205.660465842143 10126.64885587068 14408.526684542969 0.6737081921909446 1.4684391545544648 0.803454927453153 0.7793790557212266 1.061977401706482 0.770421918906503 0.6785339297341976 0.5000969650541827 0.7028233404831212 1.0 13.814635202669916 -6.929457736587341 4.71781831526391 0.6836364803498927 0.966544685211665 0.18629174972359397 0.23307089718152696 0.30169527318081113 12.859684833822561 0.08289405260551348 0.07221001112874857 1.1763654572414549e-07 6.929457736587341 0.28290820486177237 PAAS(ph)SPETPSAGQQEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PAASSPETPSAGQQEAK 17 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 PAAS(0.506)S(0.494)PETPSAGQQEAK 243.04 2.4208999999999995e-113 0.0 20809.0 28490.0 16869.0 14825.0 17633.0 9983.3 17075.0 11585.0 10402.0 13674.0 True False 24331.55270351577 31318.298916149397 17271.220936038753 13994.403313298493 14177.94022954962 9459.75817340477 15457.532387705347 11280.90602532214 10554.10957134939 16152.987956675552 1.5063190023280033 1.9388548422217124 1.069227624162319 0.866366232107232 0.8777286448536166 0.585635190144207 0.9569457012637224 0.6983789039884769 0.6533843521493923 1.0 13.97951343682525 -5.438411349327998 3.4855864053011936 0.7980904380385299 1.7192893445376305 0.8337861114694978 0.16090938184802175 0.08257364765146559 1.8843941072713466 0.04218387944812857 0.09472367165978908 3.644086276490257e-06 5.438411349327998 0.9211989064991006 PAAS(ph)SPETPSAGQQEAK ddPTM_PC-9_Lapatinib_30min_R1 1 PAASSPETPSAGQQEAK 17 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 PAAS(0.5)S(0.5)PETPSAGQQEAK 248.67 1.5995999999999998e-47 5279200.0 10215.0 25858.0 17627.0 18836.0 20538.0 19613.0 26236.0 30148.0 21154.0 21779.0 True False 10069.332226798426 25798.127389710793 16177.776102187705 20221.262275054007 19329.99521926159 18774.197710136057 27594.371706266073 31548.786140685028 18771.41375850455 25543.471131306662 0.39420375465170127 1.0099695243882503 0.6333429007759189 0.7916411270459779 0.7567489602292269 0.7349900729476806 1.080290598110833 1.2351017596045557 0.7348810841725374 1.0 14.640666967379838 -7.2553155536506635 23.46265720068537 1.0321601838900318 0.7342904946315935 0.37425385046436854 0.18399817313540612 216.6478582906749 830061.7063535874 0.06742762243097838 0.05076698255505759 5.5550048998283134e-08 7.2553155536506635 -0.2978696892584384 PAASS(ph)PETPSAGQQEAK ddPTM_PC-9_AZD4547_30min_R2 2 PAASSPETPSAGQQEAK 17 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 PAAS(0.01)S(0.906)PET(0.077)PS(0.007)AGQQEAK;PAAS(0.006)S(0.993)PET(0.001)PSAGQQEAK 260.08 2.6603999999999995e-151 5153500.0 33199.0 36577.0 29700.0 17900.1 24288.0 33201.0 34444.0 38622.0 38164.0 30150.0 True False 43755.59141790207 48399.7999477803 29306.158594364726 13773.50849878816 20916.03044139713 31124.936221487078 37509.44927313048 32653.857345268272 40181.27112664982 29094.457676945774 1.5039150034603899 1.663540200171249 1.0072763314501203 0.47340660725572425 0.7189008529954773 1.0697891868989962 1.2892300550717148 1.1223394403100677 1.3810627292939424 1.0 14.828456733936575 -7.1660084152046695 7.533359981150342 1.2079438672378535 1.0525155236088624 0.03050469450150073 0.3336324148291396 1.2203336888117815 84.88505290994182 0.1473745908214773 0.11401170481351974 6.823254727806486e-08 7.1660084152046695 -0.15542834362899116 PAASS(ph)PETPSAGQQEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PAASSPETPSAGQQEAK 17 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 PAAS(0.031)S(0.967)PET(0.002)PSAGQQEAK 159.18 2.0683000000000002e-05 4801500.0 19312.0 34679.0 21469.0 21178.0 20654.0 14284.0 20987.0 14324.0 15394.0 16286.0 True False 22581.140170613522 38121.701934473356 21980.902381635893 19991.46532000238 16606.99696597958 13534.921894455128 18998.95942727801 13948.010177532526 15619.108127413232 19238.522880094926 1.1737460464793283 1.9815295681518172 1.1425462608867107 1.0391372271457744 0.8632158024544573 0.7035322814964651 0.9875477210849289 0.7250042149526869 0.8118662864482954 1.0 14.231710413825317 -5.603175645342771 2.523021216999351 0.8515838118568082 1.5791279081291854 0.619694799310806 0.21494815843192605 0.15814108633434945 2.0215863323214585 0.05749421417519574 0.12104831407183594 2.493586021166265e-06 5.603175645342771 0.7275440962723771 PAASS(ph)PETPSAGQQEAK ddPTM_PC-9_Lapatinib_30min_R1 1 PAASSPETPSAGQQEAK 17 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 PAAS(0.136)S(0.864)PETPSAGQQEAK 143.05 0.00011472 4375700.0 9880.3 28202.0 16965.0 19648.0 22974.0 21969.0 22616.0 26804.0 21309.0 22678.0 True False 9739.405110174885 28136.700001725723 15570.2031867938 21092.979463806587 21622.714488621852 21029.43708224031 23786.94581906212 28049.41169281282 18908.956026282183 26597.86208346444 0.36617247956292515 1.0578556995833872 0.5853930341444098 0.793032891050286 0.8129493423482493 0.7906438877023146 0.8943179622639734 1.0545739204449365 0.7109201471511369 1.0 14.699022667172917 -3.337697769130624 0.24787542886890465 0.9567191080704589 2.5037235725123127e-17 0.2791063731062817 0.17447214167171413 30.981304581616826 0.9085777680882458 0.2285706658906265 10.24654373508079 0.00045951768559879827 3.337697769130624 -0.9567191080704589 PAEKPAETPVAT(ph)SPTATDSTSGDSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PAEKPAETPVATSPTATDSTSGDSSR 26 1 P54727;H0Y579;P54727-2 P54727 RAD23B UV excision repair protein RAD23 homolog B 1 PAEKPAETPVAT(0.496)S(0.496)PT(0.005)AT(0.002)DSTSGDSSR 76.90899999999999 4.6299999999999994e-05 9117300.0 12292.0 21376.0 15324.0 14650.0 14169.0 10232.0 14018.0 13640.0 12611.0 11241.0 True False 14372.792821933574 23498.06801093751 15689.38227659362 13829.207995940827 11392.686163017559 9695.415907593448 12690.113558468725 13281.964452774617 12795.412017331973 13278.90431629296 1.0823779191102714 1.7695788335567593 1.1815268717120773 1.0414419493160032 0.8579537807979347 0.7301367399490453 0.9556596881941684 1.0002304509776385 0.9635894432669606 1.0 13.696848489889067 -5.659263888448991 2.7496392945590755 0.9177623549956581 1.4335659821252005 0.5514744525193984 0.17669356324272537 0.17396571655321075 2.6429923977674776 0.048585600605916976 0.09430187437845722 2.1914729356360462e-06 5.659263888448991 0.5158036271295424 PAEKPAETPVATS(ph)PTATDSTSGDSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PAEKPAETPVATSPTATDSTSGDSSR 26 1 P54727;H0Y579;P54727-2 P54727 RAD23B UV excision repair protein RAD23 homolog B 1 PAEKPAETPVAT(0.237)S(0.694)PT(0.052)AT(0.016)DSTSGDSSR 123.07 4.6026e-07 0.0 6371.8 15646.0 7560.1 8343.5 11567.0 7300.9 11167.0 7657.4 8377.2 9020.8 True False 7450.419891213505 17199.231479188275 7740.361455838914 7876.040744991971 9300.529384404272 6918.027951500098 10109.180917921263 7456.401363685951 8499.700701894648 10656.199631386491 0.6991629426000273 1.6140117559856995 0.7263716637815846 0.7391040912741619 0.872781076380245 0.649202172519734 0.9486666229624627 0.6997242564529348 0.7976296424533801 1.0 13.379405394521857 PAEKPAETPVATS(ph)PTATDSTSGDSSR ddPTM_PC-9_Lapatinib_30min_R1 1 PAEKPAETPVATSPTATDSTSGDSSR 26 1 P54727;H0Y579;P54727-2 P54727 RAD23B UV excision repair protein RAD23 homolog B 1 PAEKPAETPVAT(0.054)S(0.694)PT(0.243)AT(0.008)DSTSGDSSR 125.85 5.1354999999999994e-11 11034000.0 11945.0 14350.0 8991.2 13152.0 18283.0 20558.0 18016.0 19443.0 16350.0 14378.0 True False 11774.662109555282 14316.773456661374 8251.978243035683 14119.241953785853 17207.62988576099 19678.78226303865 18948.780327034983 20346.392760161165 14508.490826867217 16863.218142519254 0.6982452584104581 0.8489941442768137 0.4893477729632745 0.837280395382262 1.020423844389069 1.1669648163668225 1.1236752182702987 1.206554560831978 0.8603631112548571 1.0 14.041592263113792 -6.180795958031685 2.998450376303546 1.0859094983401771 0.6931174819743419 0.6612280937346908 0.12359055305019377 0.1521088713293475 2.669068925334955 0.03792871940634182 0.0500817791459427 6.594836637195459e-07 6.180795958031685 -0.3927920163658353 PAETPVAT(ph)SPTATDSTSGDSSR ddPTM_PC-9_AZD4547_30min_R2 1 PAETPVATSPTATDSTSGDSSR 22 0 P54727;H0Y579;P54727-2 P54727 RAD23B UV excision repair protein RAD23 homolog B 1 PAETPVAT(0.913)S(0.059)PT(0.001)AT(0.006)DS(0.003)T(0.01)S(0.003)GDS(0.003)S(0.002)R 128.72 6.7187e-07 0.0 6541.3 11648.0 7556.8 12982.0 7292.9 10693.0 10065.0 9856.9 11192.0 11152.0 True False 8621.297332507682 15412.988210945261 7456.591894474592 9989.200469900612 6280.4067196173055 10024.365019618726 10960.765501511394 8333.742594028656 11783.586271079155 10761.571874404617 0.8011187801488948 1.4322246220929489 0.6928905908447623 0.9282287556578034 0.5835956673350535 0.9314963591388292 1.0185097148847317 0.7743982655405272 1.0949688770936246 1.0 13.393601198130188 -5.283674136157701 24.977462279259207 0.8681604919036227 1.116671884226152 0.17750593794779068 0.20461760591470884 1058.3306576094415 1188876.595073119 0.05045542477382879 0.10516859172275733 5.203863111408392e-06 5.283674136157701 0.2485113923225294 PAETPVATS(ph)PTATDSTSGDSSR ddPTM_PC-9_Lapatinib_30min_R1 1 PAETPVATSPTATDSTSGDSSR 22 0 P54727;H0Y579;P54727-2 P54727 RAD23B UV excision repair protein RAD23 homolog B 1 PAET(0.002)PVAT(0.138)S(0.638)PT(0.022)AT(0.198)DSTSGDS(0.002)SR 104.9 4.2053e-05 8600700.0 16383.0 23534.0 18907.0 21489.0 29683.0 21163.0 25879.0 24327.0 24351.0 26638.0 True False 16149.37541572575 23479.508468924647 17352.539443130576 23069.372745202574 27937.104299023347 20257.907823362533 27218.887993080505 25457.32123007976 21608.333952602075 31242.342807096124 0.5169066710342131 0.7515284181438439 0.555417356191011 0.7384008583364878 0.8942064451286268 0.6484119308351396 0.8712178904489274 0.8148339382633494 0.6916361582107133 1.0 14.931215022192202 -3.8049904320599035 0.09223377822836083 1.1440755404200922 8.390563754431565e-17 0.4950396679070953 0.1025393193263479 80.3217428282549 0.8962960809146437 2.2420493900395275 12.20881763271238 0.00015667855875753044 3.8049904320599035 -1.1440755404200922 PAGPAGAGT(ph)DK ddPTM_PC-9_AZD4547_30min_R2 1 PAGPAGAGTDK 11 0 D6R9L0 D6R9L0 GNB2L1 1 PAGPAGAGT(1)DK 85.212 0.02833 257990000.0 47765.0 47656.0 58665.0 60166.0 64259.0 58543.0 60253.0 56659.0 51399.0 62552.0 True False 62953.276426280674 63059.87003612701 57887.06376896994 46295.65825543372 55337.7470410795 54882.29695534825 65615.40027447262 47903.65344429479 54115.84620686178 60362.07351934697 1.0429276655995454 1.044693569314105 0.9589972708677121 0.7669660029255829 0.9167635207783725 0.9092182185848474 1.0870302567296974 0.7936051671409354 0.8965206635838449 1.0 15.881354744802683 -5.402963965614116 4.280151627711957 0.9063283626276271 1.0421840546387355 0.2702212111089214 0.08621612209339594 0.28905874619811506 8.624065155539396 0.02325910092824346 0.05104302673156321 3.953994258830927e-06 5.402963965614116 0.13585569201110848 PAGPAGAGT(ph)DK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PAGPAGAGTDK 11 0 D6R9L0 D6R9L0 GNB2L1 1 PAGPAGAGT(1)DK 86.898 0.026082 280630000.0 80721.0 95524.0 79378.0 96209.0 109440.0 75712.0 96257.0 88580.0 72120.0 58409.0 True False 94385.47098757722 105006.9914238771 81270.67256274146 90818.72164378659 87996.0176216135 71741.52943664136 87138.8401196695 86254.86885826786 73174.6185623648 68998.08933461043 1.3679432560784277 1.5218825975693226 1.1778684503655512 1.3162498051700486 1.2753399183979062 1.0397611024955553 1.262916712042335 1.2501051795792435 1.0605310852522314 1.0 16.07426879150333 -1.5228787454406212 0.1416036929608209 0.9661243927954528 2.6394597114473335 0.5774567711346175 0.09978792146067202 54.78467897671566 0.5173518249096928 0.4176016980407453 18.590028208740883 0.029999999988927998 1.5228787454406212 1.6733353186518807 PAGPAGAGT(ph)DK ddPTM_PC-9_Lapatinib_30min_R1 1 PAGPAGAGTDK 11 0 D6R9L0 D6R9L0 GNB2L1 1 PAGPAGAGT(1)DK 85.064 0.028526999999999997 280330000.0 44058.0 69296.0 68237.0 66089.0 83429.0 76612.0 80505.0 81589.0 82457.0 79988.0 True False 43429.72484075232 69135.54936953353 62626.81726243733 70949.40552644106 78521.870247725 73335.48335129478 84673.15498600977 85379.92279528815 73169.82434929613 93813.81922268949 0.4629352605042281 0.7369441937485117 0.6675649470551629 0.756278830926025 0.8369968401066223 0.7817130137002045 0.9025659086004998 0.9100996367349519 0.7799471864119517 1.0 16.517512833799366 -3.9812810841490935 0.3224683341796593 0.9255302997469388 9.119911261172044e-24 0.7648060196236297 0.06842437487323284 5.8834211958129945 0.33129121273921497 0.06604078422325421 2.3468315507323467 0.00010440442739875538 3.9812810841490935 -0.9255302997469388 down PAMPQDSVPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 PAMPQDSVPSPR 12 0 P53396 P53396 ACLY ATP-citrate synthase 1 PAMPQDS(0.002)VPS(0.998)PR;PAMPQDS(0.009)VPS(0.991)PR 72.705 0.021484 14679300.0 45801.0 58763.0 70749.0 72377.0 58907.0 58588.0 55118.0 84790.0 52029.0 61876.0 True False 60364.765280018386 77756.9905769039 69810.82203342459 55691.600863503045 50728.77985883481 54924.48309823454 60023.39522228565 71687.65378036586 54779.14672069131 59709.74007358859 1.0109701567218767 1.3022496912743748 1.1691697526632512 0.9327054647175915 0.8495896950198527 0.9198580169758482 1.005252998058784 1.2006023421307013 0.9174239689065699 1.0 15.8656786679859 -5.752103267717702 24.148384122777607 0.9771500218195182 1.1749419795492633 0.3754368256392785 0.10930082859361188 137.14688848106442 354732.28824453626 0.031245819934786055 0.053134015191469035 1.7696881070545342e-06 5.752103267717702 0.19779195772974512 PAMPQDSVPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PAMPQDSVPSPR 12 0 P53396 P53396 ACLY ATP-citrate synthase 1 PAMPQDS(0.002)VPS(0.998)PR 69.71600000000001 0.027725 8880100.0 24884.0 33592.0 30320.0 33035.0 30526.0 22064.0 28396.0 23879.0 19520.0 19453.0 True False 29096.369718597074 36926.79175820607 31042.943789240326 31184.156050915044 24544.649432724542 20906.92499854788 25706.125310763153 23252.201551891863 19805.443071788115 22979.67491013674 1.2661784743422178 1.606932730885458 1.3508869864624036 1.3570320804303095 1.0681025527431403 0.9098007295710465 1.1186461693339156 1.0118594646278007 0.8618678527541564 1.0 14.488070768096964 -6.257369171979217 2.5102495855685727 0.987380851242657 1.4237438745568043 0.7904613867762008 0.10186730882342664 0.12555617712470907 1.563974824024419 0.03277573714690806 0.04166051884548106 5.528799338774533e-07 6.257369171979217 0.43636302331414734 PAPAVGEAEDKENQQAT(ph)SGPNQPSVR ddPTM_PC-9_Lapatinib_30min_R1 2 PAPAVGEAEDKENQQATSGPNQPSVR 26 1 P16989-2;P16989;P16989-3 P16989-2 YBX3 Y-box-binding protein 3 1 PAPAVGEAEDKENQQAT(0.487)S(0.487)GPNQPS(0.026)VR;PAPAVGEAEDKENQQAT(0.358)S(0.358)GPNQPS(0.284)VR 66.308 0.00032156 12573200.0 17239.4 28846.0 31402.0 30646.0 28339.0 26092.0 29248.0 36281.0 29617.0 35449.0 True False 16993.562994681233 28779.20885929295 28820.248775225406 32899.809072059084 26672.155736617686 24976.105983422713 30762.318328436908 37966.74771030225 26281.221579163695 41576.31241717661 0.4087318476965409 0.692202054153395 0.6931891526608494 0.7913113780256047 0.641522881322166 0.6007292261230994 0.7399001147520705 0.9131821824250308 0.6321200715315487 1.0 15.343474184562119 -14.522878745280336 0.04669194338243814 2.317374528737794 1.4761093223187585e-14 0.5021026572994844 0.11088054488624596 563.4065921298996 1.9450177705398974 95.68223249258023 23.49845733542859 3.0000000000000132e-15 14.522878745280336 -2.3173745287377794 PAPAVGEAEDKENQQATS(ph)GPNQPSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PAPAVGEAEDKENQQATSGPNQPSVR 26 1 P16989-2;P16989;P16989-3 P16989-2 YBX3 Y-box-binding protein 3 1 PAPAVGEAEDKENQQAT(0.168)S(0.562)GPNQPS(0.27)VR 88.708 8.8622e-05 0.0 10121.0 9107.0 7861.3 7979.4 9522.5 5869.1 7033.4 6730.3 5626.5 4764.3 True False 11834.285401138113 10011.082773933756 8048.743206146269 7532.340087563841 7656.634482838217 5561.3140640399415 6367.145434593663 6553.636756342299 5708.776918207778 5628.029875821952 2.1027403304979364 1.7787899131348652 1.4301173561149194 1.3383617809000652 1.3604466663780805 0.988145796441376 1.1313275826674187 1.164463746807166 1.0143473016610511 1.0 12.45841427165618 -1.5228787455878774 0.37883115102589665 1.0234566385745878 17.01781086626664 0.9481858914666883 0.0789123422000133 13.588426636315658 0.18577387782328303 0.061389718135533004 159.38661445456793 0.029999999978755902 1.5228787455878774 15.994354227692051 up PAPAVGEAEDKENQQATSGPNQPS(ph)VR ddPTM_PC-9_AZD4547_30min_R2 1 PAPAVGEAEDKENQQATSGPNQPSVR 26 1 P16989-2;P16989;P16989-3 P16989-2 YBX3 Y-box-binding protein 3 1 PAPAVGEAEDKENQQAT(0.198)S(0.198)GPNQPS(0.604)VR 71.296 0.00010170000000000002 4922700.0 11353.0 12112.0 11716.0 15590.0 14669.0 13562.0 11145.0 13254.0 12776.0 12451.0 True False 14963.01784293026 16026.967136930727 11560.638184901589 11995.966363098949 12632.462555371148 12713.965996078663 12136.883409274164 11205.898846620721 13451.31327727906 12015.094279789442 1.2453516796867348 1.33390273631807 0.9621762356328495 0.9984080094383722 1.0513827241971943 1.0581661450185031 1.0101363440559583 0.9326517616653357 1.1195345591174826 1.0 13.55256034857079 -5.260225971239137 24.999998667974445 1.0160040082942434 1.289627227411287 0.8092937149643095 0.05302238933578161 39.47246767467939 813231.178556226 0.013306020591380125 0.03146336381781819 5.492550122214758e-06 5.260225971239137 0.27362321911704357 PAPPPQS(ph)QSPEVEQLGR ddPTM_PC-9_AZD4547_30min_R2 2 PAPPPQSQSPEVEQLGR 17 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 PAPPPQS(0.5)QS(0.5)PEVEQLGR;PAPPPQS(0.5)QS(0.5)PEVEQLGR 138.28 4.135e-05 14073200.0 5016.4 3957.7 8771.3 4006.1 4938.5 8870.0 4193.0 5314.6 2603.0 7704.799999999999 True False 6611.510852398077 5236.949127958282 8654.986830934393 3082.555538628013 4252.874519715074 8315.357497803985 4566.168877082687 4493.350687358568 2740.5892658701778 7435.057297158602 0.8892346875288705 0.7043589468987207 1.1640780272456006 0.41459741538320755 0.5720029247576023 1.1183985765626583 0.6141403750617637 0.6043464774744584 0.3686036510999757 1.0 12.86012814489648 -7.431621070291229 20.641768115638797 0.6134092548891584 0.7989840678417656 0.0819901028721135 0.25713011124733015 32.15523589654104 7267.045394356435 0.10662322678460835 0.07188503548080748 3.70151002300305e-08 7.431621070291229 0.18557481295260714 PAPPPQSQS(ph)PEVEQLGR ddPTM_PC-9_Lapatinib_30min_R1 1 PAPPPQSQSPEVEQLGR 17 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 PAPPPQS(0.238)QS(0.762)PEVEQLGR 147.6 7.9848e-05 10706000.0 11345.0 9572.9 11551.0 10074.0 5149.4 11228.0 4600.5 15244.0 11380.0 5804.8 True False 11183.218219581806 9550.73453820722 10601.321368149436 10814.875565878849 4846.522416109921 10747.804613746379 4838.691379580619 15952.291890958011 10098.264563287396 6808.151945590197 1.6426217142267872 1.4028380410036911 1.557151111325617 1.588518536646924 0.7118704833327244 1.5786669715425474 0.7107202392441836 2.3431163138611635 1.4832607503462496 1.0 12.733047520379154 PAPPQEES(ph)PSSEAK ddPTM_PC-9_AZD4547_30min_R2 1 PAPPQEESPSSEAK 14 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 PAPPQEES(0.759)PS(0.184)S(0.057)EAK 123.02 4.9287e-05 21742000.0 44524.0 48020.0 44784.0 22170.0 24004.0 39432.0 53750.0 35098.0 42792.0 35976.0 True False 58681.705843268464 63541.52591771903 44190.134898654236 17059.04902308554 20671.458939200293 36966.31080647201 58533.64587245275 29674.410571804274 45053.897758400526 34716.49119024216 1.6903121205913305 1.8302980439330456 1.2728859796486247 0.4913817162455739 0.5954362964253272 1.0648055013365583 1.6860472895055976 0.8547641064643343 1.2977664566246236 1.0 15.08333352093078 -5.420524785088774 4.33582883115999 0.9994038480816099 1.7490213017720204 0.4676973986984788 0.3204571405383385 0.2084345323328472 6.552906392652358 0.09314552877811004 0.20255542715560176 3.7973026723166976e-06 5.420524785088774 0.7496174536904106 PAPPQEES(ph)PSSEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PAPPQEESPSSEAK 14 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 PAPPQEES(0.492)PS(0.492)S(0.016)EAK;PAPPQEES(0.981)PS(0.014)S(0.005)EAK 188.0 3.9329e-06 37221000.0 39018.0 58043.0 38900.0 37148.0 35675.0 27669.0 37773.0 34546.0 26176.3 31245.0 True False 45622.9767593723 63805.12544717658 39827.52352907151 35066.717995440944 28684.7398451303 26217.9889315093 34194.86798716218 33639.204104512595 26559.078866805696 36909.47116471611 1.236077768651043 1.7286924855258174 1.0790597175270542 0.9500737043602846 0.7771647476908772 0.7103322833997303 0.9264523957701952 0.9113976180907801 0.7195735411184935 1.0 15.171703446487964 -5.514943377141422 3.1219525197866917 0.8469311090132203 1.4817017616760155 0.737432137139284 0.14680268467067664 0.11078829434234486 2.1998149283074158 0.03878121511881807 0.0830885008003901 3.055319436588774e-06 5.514943377141422 0.6347706526627952 PAPPQEES(ph)PSSEAK ddPTM_PC-9_Lapatinib_30min_R1 3 PAPPQEESPSSEAK 14 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 PAPPQEES(0.989)PS(0.009)S(0.002)EAK;PAPPQEES(0.745)PS(0.201)S(0.054)EAK;PAPPQEES(0.939)PS(0.059)S(0.002)EAK 170.42 4.9287e-05 104735000.0 52513.0 110722.0 71792.0 84076.0 96984.0 89635.0 102400.0 121796.0 72488.0 89045.0 True False 51764.15499029525 110465.63001173944 65889.53888513397 90259.22950931426 91279.5917978802 85801.5199993905 107701.77095295185 127455.0867981579 64323.638107519975 104436.30960499549 0.4956528547023574 1.0577320323702395 0.630906426455941 0.8642514260672124 0.8740216132025603 0.8215679041505155 1.0312674907827284 1.2204097145928006 0.6159125916150066 1.0 16.672263858565216 -6.569214693460742 1.1232220281238352 0.9729550470925145 0.7615263914584972 0.16407582762901007 0.19703190902176348 0.8990746476880354 2.408642925855461 0.09168694345823507 0.1001299947272601 2.6964061346432956e-07 6.569214693460742 -0.21142865563401725 PAPPQEESPS(ph)SEAK ddPTM_PC-9_AZD4547_30min_R2 3 PAPPQEESPSSEAK 14 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 PAPPQEES(0.086)PS(0.888)S(0.025)EAK;PAPPQEES(0.123)PS(0.868)S(0.009)EAK;PAPPQEES(0.09)PS(0.883)S(0.026)EAK 212.43 6.2276e-12 94368000.0 112409.0 125142.0 96437.0 59803.0 67636.0 102941.0 109901.0 103915.0 106622.0 94064.0 True False 148152.72374755083 165591.70421481045 95158.1823691836 46016.34229713961 58245.90888234256 96504.08299678001 119681.97609355212 87857.32447914529 112257.82124687279 90770.84799085351 1.6321619443555202 1.8242828824458734 1.0483341785985318 0.5069506710103273 0.6416807837711475 1.0631616331986258 1.318506753463533 0.9679024314942855 1.2367166742585065 1.0 16.469941414820028 -5.3053998419442765 5.829227690004889 0.9554292896795755 1.7291620468382354 0.6249732878029843 0.2341327740483315 0.12464677607614956 11.121958742719395 0.06859566395464438 0.14979639296454136 4.949942545435039e-06 5.3053998419442765 0.7737327571586599 PAPPQEESPS(ph)SEAK ddPTM_PC-9_Lapatinib_30min_R1 1 PAPPQEESPSSEAK 14 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 PAPPQEES(0.261)PS(0.663)S(0.076)EAK 173.19 0.00014868 40990000.0 17410.0 43211.0 32979.0 31716.0 36954.0 37030.0 38758.0 39988.0 31235.0 36027.0 True False 17161.73020739703 43110.947584375936 30267.59392262143 34048.50044147447 34780.43837435936 35446.31322114606 40764.699595649545 41845.988463371126 27716.985380868366 42254.21894704003 0.4061542405719757 1.020275576230854 0.7163212260663906 0.8058012025769468 0.8231234475769614 0.8388822253601051 0.9647486241963814 0.9903387047768989 0.6559578208180317 1.0 15.366807776567844 -4.748856856654206 24.99698098149044 0.8620488031508658 0.4061531758040179 0.578227121968286 0.11832056395803565 433.1428045360437 860448.5006826258 0.02844352241993887 0.4960780826090628 1.7829663358419334e-05 4.748856856654206 -0.45589562734684796 PAPPQEESPSS(ph)EAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PAPPQEESPSSEAK 14 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 PAPPQEES(0.253)PS(0.128)S(0.619)EAK 81.632 0.010192 30120000.0 42317.0 60910.0 38024.0 38744.0 41726.0 25208.0 37232.0 26956.0 21862.0 28736.0 True False 49480.43230115221 66956.74225983373 38930.63636682303 36573.29928974278 33550.08983259724 23886.048103852187 33705.115423662995 26248.433562242855 22181.690391159413 33945.609325949146 1.4576386544143642 1.972471361963439 1.146853367485826 1.077408831833369 0.9883484344159479 0.7036564839504266 0.9929153163822483 0.7732497393168808 0.6534479961213421 1.0 15.050937361579944 -5.5705332509823755 1.779282258102195 0.8519195960978985 1.7256853348637435 0.7555722820481602 0.1838952962212608 0.16399185459516175 1.019244484480511 0.053351697540494424 0.1406610666954221 2.688232015495876e-06 5.5705332509823755 0.8737657387658451 PAPS(ph)RDPSPPR ddPTM_PC-9_AZD4547_30min_R2 1 PAPSRDPSPPR 11 1 Q5C9Z4 Q5C9Z4 NOM1 Nucleolar MIF4G domain-containing protein 1 1 PAPS(0.914)RDPS(0.086)PPR 71.268 0.014227000000000002 3273400.0 8745.6 9605.4 8994.2 10610.0 8350.9 9067.4 10059.0 10721.0 8871.3 11567.0 True False 11526.5188802194 12710.15770616531 8874.931031294125 8164.028422865931 7191.52168202665 8500.414044598412 10954.231513134924 9064.315794071283 9340.2188068821 11162.042850720796 1.0326531652290754 1.1386945809247222 0.7950991722560016 0.7314098800775284 0.6442836475549144 0.7615464443454893 0.9813823203901737 0.8120660272761763 0.8367839948113932 1.0 13.446313469520488 -3.2263004380813998 11.066300374181955 0.8629542643624508 0.9631674170676379 0.0 0.14863387773435882 0.0 0.0 0.03728062526488419 0.0 0.0005938811788328308 3.2263004380813998 0.10021315270518705 PAPT(ph)T(ph)LS(ph)TTTGPAPTT(ph)PVATTVPAPTTPR ddPTM_PC-9_AZD4547_30min_R2 1 PAPTTLSTTTGPAPTTPVATTVPAPTTPR 29 0 Q9H1U4 Q9H1U4 MEGF9 Multiple epidermal growth factor-like domains protein 9 4 PAPT(0.962)T(0.886)LS(0.325)T(0.325)T(0.325)T(0.08)GPAPT(0.127)T(0.337)PVAT(0.331)T(0.287)VPAPT(0.008)T(0.008)PR 46.034 0.039859 0.0 2791.8 3248.4 4680.2 5311.0 4226.7 3181.2 3815.2 4032.1 2742.1 4155.4 True False 3679.5343269525856 4298.381774075772 4618.137490011644 4086.631004132042 3639.89566315272 2982.27906110643 4154.745408978268 3409.0315934404257 2887.0418078918997 4009.9207108053215 0.9176077514544212 1.0719368496472137 1.1516780063923442 1.0191301272167337 0.907722602430638 0.7437251946329613 1.0361165989598484 0.8501493768328856 0.7199747865618242 1.0 11.969357994843808 -6.270943418256436 3.680029655086577 0.8676015840640507 1.0534126285312118 0.3663241604978986 0.10615501055504652 0.2426283279291049 7.292582454555479 0.03346366414781297 0.04093933464941352 5.358664679422013e-07 6.270943418256436 0.185811044467161 PARS(ph)PDAPGR ddPTM_PC-9_Lapatinib_30min_R1 1 PARSPDAPGR 10 1 E7EUN2 E7EUN2 AGAP1 1 PARS(1)PDAPGR 61.11 0.030802999999999997 3609200.0 4151.0 3064.3 4964.9 3888.4 4634.6 3088.4 2917.5 2971.6 3624.5 2771.4 True False 4091.8059787998286 3057.204801620032 4556.705087068228 4174.365907322148 4362.001939974178 2956.3163314120325 3068.553874562864 3109.6713843591456 3216.2706423229524 3250.432797341626 1.25884958524487 0.9405531485285202 1.4018764180557552 1.2842492577407423 1.3419757342904155 0.9095146756548428 0.944044706007301 0.9566945629217123 0.9894899672909363 1.0 11.666416111420824 -6.768382498250611 24.99970938326981 0.9562481495818907 1.239399520568344 0.6031249072546355 0.11574629533301176 120.2146821803499 432847.68977026315 0.041867889595155784 0.03771449265991562 1.704580444427215e-07 6.768382498250611 0.28315137098645315 PARSVMES(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 PARSVMESR 9 1 Q9BTC0;Q9BTC0-1 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 PARSVMES(1)R 54.722 0.044308999999999994 530000.0 362.59 0.0 0.0 589.27 0.0 0.0 673.74 0.0 0.0 0.0 True False 357.41940010913765 0.0 0.0 632.6068815470949 0.0 0.0 708.6229605648617 0.0 0.0 0.0 0.0 PAS(ph)LGTGK ddPTM_PC-9_AZD4547_30min_R2 3 PASLGTGK 8 0 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 PAS(0.992)LGT(0.008)GK;PAS(0.983)LGT(0.017)GK;PAS(1)LGTGK 104.42 0.0038583 239363000.0 639330.0 639190.0 659890.0 653230.0 626820.0 777660.0 776550.0 782170.0 765720.0 770590.0 True False 842623.6411098904 845795.6674582848 651139.4274355328 502637.9158028948 539796.8627007798 729032.7972651916 845661.4456233142 661303.5989785212 806194.395951638 743611.8786493404 1.1331497859345525 1.137415487491332 0.8756441984469506 0.6759412137362051 0.7259121030735012 0.9803942327943583 1.137234987638083 0.8893128498426897 1.0841601904154212 1.0 19.504190290863676 -6.989883613051558 24.978696467801633 1.02421903638173 0.9019747815631305 0.12003335737246656 0.15060163906092366 511.7048782033573 1263460.5871858338 0.06010913860643006 0.05295563627194925 1.0235672621913869e-07 6.989883613051558 -0.12224425481859957 PAS(ph)LGTGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 PASLGTGK 8 0 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 PAS(0.985)LGT(0.015)GK;PAS(0.986)LGT(0.014)GK;PAS(0.942)LGT(0.058)GK 99.788 0.0050921000000000004 240651000.0 619850.0 679820.0 506030.0 733000.0 605500.0 463370.0 601700.0 489270.0 433750.0 490770.0 True False 724778.3624044515 747308.0368261401 518095.67432946205 691932.3864180648 486856.6216181198 439070.0614837346 544702.6200692408 476427.1809244171 440092.77317561995 579742.7160668164 1.250172433940368 1.2890339388757608 0.8936648274676221 1.193516308600449 0.8397804890437102 0.7573533040010303 0.9395592302818392 0.8217907146064222 0.7591173825543993 1.0 19.145053263287743 -5.42694324782012 0.7726496966895329 0.8404785013813558 1.3661446385070148 0.5975029534495384 0.12142469954825828 0.8503840552385117 0.7007441992866867 0.05262037898001753 0.3320748725819082 3.741594790122846e-06 5.42694324782012 0.525666137125659 PAS(ph)LGTGK ddPTM_PC-9_Lapatinib_30min_R1 3 PASLGTGK 8 0 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 PAS(0.908)LGT(0.092)GK;PAS(0.671)LGT(0.329)GK;PAS(0.914)LGT(0.086)GK 92.23899999999999 0.0081241 320508000.0 410720.0 870840.0 704080.0 724610.0 613950.0 616750.0 562890.0 684580.0 544700.0 556760.0 True False 404863.05748317624 868823.6234842504 646193.2602273952 777900.2366281 577838.6680721415 590373.040214471 592033.6899580774 716388.0859821609 483350.150054714 652995.2241639311 0.6200092167619551 1.3305206398663287 0.9895834399933862 1.1912801316795116 0.8849048916276271 0.904100088894771 0.9066432158307032 1.0970801308683313 0.7402047245806065 1.0 19.316712914753374 -6.299146596523373 24.94329085521772 0.9253311213876959 1.051020450551513 0.07239064861149147 0.18950397697640253 1329.2536779601382 879296.8103325284 0.0553159564397054 0.06272377741807691 5.021730519097233e-07 6.299146596523373 0.12568932916381714 PAS(ph)LGTGKDFAGIQVGK ddPTM_PC-9_Lapatinib_30min_R1 1 PASLGTGKDFAGIQVGK 17 1 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 PAS(0.951)LGT(0.049)GKDFAGIQVGK 87.66799999999999 0.0013477 8556400.0 142470.0 17472.0 25601.0 22295.0 12546.0 15454.0 7156.8 6244.1 23259.0 9426.2 True False 140438.35167420167 17431.54465747648 23496.184602717836 23934.64867393975 11808.068946385027 14793.068445033528 7527.344085508653 6534.223681207752 20639.32649187185 11055.506110378017 12.703023296452207 1.5767296841447314 2.125292534609656 2.164952778730938 1.0680713147361534 1.3380724769485668 0.6808683393013178 0.5910379512226898 1.866882102529645 1.0 13.432477451399127 -4.761253384697149 7.134513992365906 1.3671769418870225 12.929003016480404 0.9766552195146759 0.5253180293942623 0.01566371790664988 4.87183334218625 0.14448760605973224 0.8755162883746762 1.7327927224884135e-05 4.761253384697149 11.561826074593382 PAS(ph)PASNVVVLPSGSTVYVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PASPASNVVVLPSGSTVYVK 20 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;Q7Z589-2 E9PMC9 C11orf30;EMSY Protein EMSY 1 PAS(0.989)PAS(0.011)NVVVLPSGSTVYVK 156.29 1.5478e-20 0.0 12055.0 20992.0 10538.0 11889.0 15165.0 8303.4 13473.0 7577.2 8661.6 9376.4 True False 14095.673402896948 23075.947028705104 10789.265885587556 11222.897874658063 12193.527112863374 7867.955086699707 12196.73990392703 7378.306528707027 8788.259513862702 11076.267096458436 1.2726014351354842 2.083368595912922 0.9740886339800666 1.013238284786985 1.100869725032378 0.7103435677544679 1.1011597858476037 0.6661365660878829 0.7934315268248353 1.0 13.435184128371436 -5.355536737303884 7.240937948558981 0.9133816518743572 1.674614634208782 0.6324135113215774 0.23135577317519368 0.13892540479890672 9.20978022178941 0.05744988681946872 0.12056634811063636 4.410250548952695e-06 5.355536737303884 0.7612329823344248 PAS(ph)PDRFAVSAEAENK ddPTM_PC-9_AZD4547_30min_R2 2 PASPDRFAVSAEAENK 16 1 G3V331;O15037 G3V331 KHNYN Protein KHNYN 1 PAS(0.999)PDRFAVS(0.001)AEAENK;PAS(1)PDRFAVSAEAENK 72.209 0.0078652 19054700.0 59615.0 71725.0 60400.0 62330.0 67696.0 70172.0 59052.0 67985.0 65296.0 67989.0 True False 78571.32993096864 94908.70359117864 59599.05653534109 47960.78148890041 58297.57891801795 65784.13374700144 64307.51360111781 57479.480389883036 68747.4132555741 65608.72580424102 1.1975743922447843 1.4465865999952652 0.9084013719938536 0.7310122380977587 0.8885644127880552 1.002673545943931 0.9801670862042697 0.8760950572548308 1.047839481911264 1.0 16.001600082157097 -5.271436073272933 24.934803827797957 0.9208132679848813 1.3220804961158057 0.705343143251953 0.10141594240264794 301.1459642946321 751150.809190554 0.02694138250510919 0.0571700296460836 5.3525893633736e-06 5.271436073272933 0.4012672281309244 PAS(ph)PDRFAVSAEAENK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PASPDRFAVSAEAENK 16 1 G3V331;O15037 G3V331 KHNYN Protein KHNYN 1 PAS(1)PDRFAVSAEAENK;PAS(1)PDRFAVSAEAENK 94.958 0.001193 14639200.0 77335.0 89064.0 63580.0 83515.0 87628.0 63512.0 78908.0 55308.0 56054.0 60597.0 True False 90426.28806412574 97905.6853165296 65095.98832849273 78835.92530928332 70457.92244286138 60181.318913514006 71433.26299555221 53856.223603669954 56873.6837062506 71582.75641441185 1.2632412132975657 1.3677272323760101 0.9093808563564459 1.101325644026348 0.9842862439518464 0.8407236872118775 0.9979116001346164 0.7523630871642016 0.7945165365942817 1.0 16.127324477772 -5.100540900196834 0.6063176559234418 0.859102285009216 1.5371403974622948 0.6342311016696317 0.11349292466613362 1.5836351065576815 0.5752479937657089 0.05923085031032669 0.7107958497151174 7.93339539568809e-06 5.100540900196834 0.6780381124530788 PAS(ph)PDRFAVSAEAENK ddPTM_PC-9_Lapatinib_30min_R1 2 PASPDRFAVSAEAENK 16 1 G3V331;O15037 G3V331 KHNYN Protein KHNYN 1 PAS(0.999)PDRFAVS(0.001)AEAENK;PAS(0.997)PDRFAVS(0.003)AEAENK 81.992 0.0031826 22023000.0 86193.0 125048.0 113275.0 119504.0 139835.0 119459.0 132091.0 127088.0 131510.0 116615.0 True False 84963.87201413972 124758.45903892598 103961.96675414492 128292.72281365738 131610.1802261877 114350.01704253005 138930.02565377307 132992.97243755372 116697.95893830627 136771.7473702797 0.621209231056459 0.9121654247873987 0.7601128796921087 0.9380060230299814 0.9622614520664257 0.8360646057475034 1.0157801470332195 0.9723716702800046 0.853231469086755 1.0 17.061410721193205 -3.9473590179667126 0.7026285048195899 0.940504337035881 4.2586459206746495e-16 0.5656805172258186 0.0768611445001915 6.475544989027482 1.0246755737730928 0.029929664140336723 6.346030677572378 0.00011288623328761785 3.9473590179667126 -0.9405043370358805 PAS(ph)PSLQLLPWR ddPTM_PC-9_AZD4547_30min_R2 2 PASPSLQLLPWR 12 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 PAS(0.913)PS(0.087)LQLLPWR;PAS(0.5)PS(0.5)LQLLPWR 139.74 7.3343e-05 41318000.0 77359.0 81733.0 98980.0 123718.0 96305.0 95638.0 88752.0 107427.0 98215.0 100837.0 True False 101957.552832841 108151.59387407186 97667.46052761686 95196.72652404601 82934.71309530419 89657.74074126016 96650.75606459426 90826.62557687692 103406.44439010358 97306.72732239419 1.0477955187521395 1.1114503267153024 1.0037071764219085 0.9783159822921865 0.8523019464063055 0.9213930342576254 0.9932587265459398 0.9334054086101615 1.0626854610730043 1.0 16.57025192904868 -5.517726433195 2.878296649754909 0.9552584059790005 1.0791064956840617 0.4078043168385235 0.05478227130737191 0.2423601246119376 4.033355479417797 0.015691376135116397 0.03440811849307308 3.0358028671919298e-06 5.517726433195 0.12384808970506123 PAS(ph)PSLQLLPWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PASPSLQLLPWR 12 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 PAS(0.832)PS(0.168)LQLLPWR 86.738 0.0089588 1437400.0 5084.2 2278.0 6539.7 8200.3 10004.0 7072.3 6623.5 6926.6 5800.0 2633.2 True False 5944.854642472724 2504.1447852224755 6695.63124995036 7740.863776731305 8043.788014314889 6701.416137927397 5996.074130012674 6744.784089339344 5884.814027478024 3110.57831560027 1.9111734344246865 0.8050415489182864 2.1525358215127457 2.488560965627865 2.5859461483330706 2.1543955682833142 1.9276396610691249 2.1683376546131923 1.8918713597289354 1.0 11.602967114369923 -8.57568872554793 15.722188518290265 0.9999999842778445 2.0236013282114818 0.3081843932635152 0.4575844860276653 238.6846496902341 71061.21376639412 0.4859898297640928 0.12548414111479086 2.6565088951292272e-09 8.57568872554793 1.0236013439336373 PAS(ph)PSLQLLPWR ddPTM_PC-9_Lapatinib_30min_R1 1 PASPSLQLLPWR 12 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 PAS(0.586)PS(0.414)LQLLPWR 74.237 0.021055 1862600.0 10449.0 8656.3 8627.3 9258.7 10280.0 10194.0 8084.9 8127.2 9807.5 8370.9 True False 10299.995343888077 8636.256869191486 7917.996696341062 9939.615684117787 9675.350611257621 9758.026383374641 8503.49656228048 8504.819381802286 8702.876072446503 9817.79891147687 1.0491145150515893 0.8796530614510573 0.806494079552295 1.0124077477792415 0.985490810974675 0.9939118198853762 0.8661306509690284 0.8662653878416955 0.886438615306427 1.0 13.261183902335075 -10.584364133816646 5.815210300397225 1.0000002616552048 0.924943341908452 0.07752704481654382 0.07480456913529965 2.647761325446565e-07 4.270209018642442e-08 0.07557607609547956 0.01832982707644225 2.6039693387084355e-11 10.584364133816646 -0.07505691974675288 PAS(ph)PVPGSER ddPTM_PC-9_AZD4547_30min_R2 1 PASPVPGSER 10 0 A0A5E8;Q99501;Q99501-2;Q99501-4 A0A5E8 GAS2L1 GAS2-like protein 1 1 PAS(0.971)PVPGS(0.029)ER 82.494 0.014837000000000001 3743700.0 16071.0 20459.0 24385.0 20061.0 24070.0 25836.0 20930.0 26651.0 23127.0 23983.0 True False 21181.243702433923 27071.971652449265 24061.63896712404 15436.246389360367 20728.295978443228 24220.47083576819 22792.729453217435 22532.700329054525 24349.446005293743 23143.36246985706 0.9152189415008866 1.169751011233091 1.0396777477111627 0.6669837371067069 0.8956475536102707 1.0465407032929637 0.9848495214515045 0.9736139404290155 1.0521135827608257 1.0 14.498310866560612 -10.472852481461842 12.926348342938821 0.9999998477943958 0.9708898362382786 0.004547295525860862 0.1256661269517862 0.0 0.0 0.1294361656250287 0.031392881332172655 3.366258930171835e-11 10.472852481461842 -0.029110011556117144 PASGPIRPIVR ddPTM_PC-9_Lapatinib_30min_R1 1 PASGPIRPIVR 11 1 P26373;P26373-2;J3QSB4 P26373 RPL13 60S ribosomal protein L13 0 84.81700000000001 0.015297999999999999 8268500.0 46030.0 50705.0 33781.0 38584.0 36615.0 28022.0 39531.0 34759.0 30693.0 31903.0 False True 45373.60375913179 50587.59568780592 31003.656578430946 41421.59607245081 34461.37768785971 26823.564382472458 41577.721753331454 36374.030033968105 27236.031128381404 37417.39104192458 1.2126340852651274 1.3519808377640412 0.828589479787425 1.1070145437462406 0.9209989453633264 0.7168742564765621 1.1111870869549778 0.9721156131172418 0.7278976532026138 1.0 15.19142134854782 -5.258523230091851 24.99985122337317 0.9279365396196548 1.2823074865600876 0.5382154267165336 0.13303542104342414 185.92732468447417 1593916.3013353923 0.03381013767233466 0.0816699056739313 5.514127069334903e-06 5.258523230091851 0.3543709469404328 PASLGT(ph)GKDFAGIQVGK ddPTM_PC-9_AZD4547_30min_R2 1 PASLGTGKDFAGIQVGK 17 1 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 PAS(0.252)LGT(0.748)GKDFAGIQVGK 79.337 0.0046524999999999995 7302400.0 16421.0 2746.6 18569.0 57292.0 44704.0 16150.0 12737.0 21899.0 9277.4 28877.0 True False 21642.53642198166 3634.3847373096028 18322.76292723093 44084.21455257635 38497.62124720922 15140.137946959912 13870.568325161503 18515.012738957837 9767.784423812524 27866.02501947474 0.7766639270170873 0.13042350800911284 0.6575305560956647 1.582005848403825 1.3815253959007205 0.5433188959092271 0.49775912838188346 0.6644296316399 0.3505266508942739 1.0 14.766219601808636 -10.788470690152707 4.041028602383557 1.0002601920220298 0.741457164437446 0.03516190188300372 0.41895849030530186 340173682.31984186 876452.4636400802 880933.5936270617 0.11236435033682723 1.6275311514376404e-11 10.788470690152707 -0.25880302758458373 PASVDGSPVS(ph)PSTNR ddPTM_PC-9_AZD4547_30min_R2 2 PASVDGSPVSPSTNR 15 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 PASVDGS(0.001)PVS(0.333)PS(0.333)T(0.333)NR;PASVDGS(0.065)PVS(0.931)PS(0.001)T(0.003)NR 166.64 0.00012298 14390900.0 31716.0 43411.0 36179.0 42568.0 40668.0 47536.0 40535.0 46278.0 45852.0 45310.0 True False 41801.02826621831 57442.75680162646 35699.242821061336 32754.605269043994 35021.95018077809 44563.566405367594 44142.536473299944 39126.798462646264 48275.643111286714 43723.71069129064 0.9560265495614646 1.3137667387655763 0.8164733106280546 0.7491268410475602 0.8009830279055923 1.0192082442409045 1.009578916688165 0.8948645447523731 1.1041067271745255 1.0 15.416128222662516 -10.030086868523359 15.465672835342632 0.9999914235481656 0.9587178358219802 0.004489567494167845 0.157025551363479 0.0 0.0 0.1605298983020839 0.03893421922171489 9.330676479174218e-11 10.030086868523359 -0.04127358772618539 PASVDGSPVS(ph)PSTNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PASVDGSPVSPSTNR 15 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 PASVDGS(0.001)PVS(0.98)PS(0.018)T(0.001)NR;PASVDGS(0.002)PVS(0.997)PSTNR 180.06 2.485e-05 11337500.0 61603.0 103921.0 71305.0 79751.0 74616.0 45254.0 63871.0 48109.0 47233.0 47549.0 True False 72031.17118528925 114237.59009003727 73005.18162571831 75282.81002623042 59995.53043543781 42880.80057488605 57820.67649400456 46846.189725699 47923.69326894307 56169.2573023231 1.282394937102188 2.033809873525113 1.2997355694553379 1.340284946639606 1.06812041527486 0.7634211779601463 1.0294007660238933 0.8340183220432486 0.8532014765835437 1.0 15.777493106565329 -6.02321965440301 1.343864867714163 0.8910789516578476 1.638768720480285 0.6670375303385507 0.20306181868728562 0.2347579743816378 0.8598907930753548 0.06990879464646954 0.12493426712539932 9.479389001783543e-07 6.02321965440301 0.7476897688224374 PASVDGSPVS(ph)PSTNR ddPTM_PC-9_Lapatinib_30min_R1 2 PASVDGSPVSPSTNR 15 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 PASVDGS(0.045)PVS(0.935)PS(0.017)T(0.003)NR;PASVDGS(0.008)PVS(0.631)PS(0.286)T(0.075)NR 191.63 8.2014e-08 13905200.0 39192.0 89405.0 78571.0 73138.0 74553.0 62063.0 61020.0 73095.0 56914.0 68346.0 True False 38633.114893067446 89197.98821552693 72111.19567283081 78516.81250121577 70167.93911683741 59408.71016591924 64179.31702684691 76491.26054641679 50503.74598901049 80159.51503467956 0.48195295189040915 1.1127560861232386 0.8995962069086024 0.9795070799423736 0.8753538377381715 0.7411311076447649 0.8006450263462909 0.9542380653541159 0.6300405630842572 1.0 16.290586159799396 -6.543369607291142 24.39847364084508 0.8194184401097997 0.8930406592739958 0.007585495619118032 0.17830276161417052 728.8297764249014 867809.9702732699 0.05588370982288701 0.055890349826107626 2.8617414417862583e-07 6.543369607291142 0.07362221916419609 PAT(ph)STPDLASHR ddPTM_PC-9_AZD4547_30min_R2 1 PATSTPDLASHR 12 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 PAT(0.614)S(0.325)T(0.06)PDLASHR 111.83 0.0021518 23878000.0 36627.0 35941.0 40759.0 52987.0 46177.0 44144.0 46103.0 50772.0 39717.0 52717.0 True False 48273.62411107255 47558.22538543814 40218.5090285425 40771.66579098938 39766.12062303997 41383.668701585055 50206.07768665473 42926.35402449276 41816.35953613749 50871.39387580601 0.9489345668200978 0.9348716786008181 0.790591842769814 0.8014654737105606 0.7816990570402355 0.8134958676897345 0.9869216048851436 0.8438210702323248 0.8220014501317799 1.0 15.634567004124728 PAT(ph)STPDLASHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PATSTPDLASHR 12 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 PAT(0.363)S(0.363)T(0.273)PDLASHR;PAT(0.433)S(0.433)T(0.133)PDLASHR 111.12 0.0023312 37127000.0 54411.0 67293.0 68198.0 82797.0 81250.0 74622.0 75503.0 83221.0 69737.0 57105.0 True False 63621.7076337641 73973.4043160564 69824.09896235514 78158.15252149562 65329.64575800521 70708.69095547682 68350.8092456174 81036.53692993808 70756.77169555787 67457.68445706877 0.9431350652756848 1.0965897349046179 1.0350799842053933 1.1586248942659279 0.9684537244912715 1.0481932714497049 1.0132397783252853 1.2012943756098111 1.0489060255335134 1.0 16.04169517700958 PATS(ph)TPDLASHR ddPTM_PC-9_AZD4547_30min_R2 1 PATSTPDLASHR 12 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 PAT(0.226)S(0.72)T(0.054)PDLASHR 103.3 0.0012125999999999999 19872000.0 42843.0 48199.0 62491.0 74578.0 59700.0 64256.0 51949.0 65203.0 53285.0 66215.0 True False 56466.18281024056 63778.38416718326 61662.32850910597 57385.19431861412 51411.6854970112 60238.062162220194 56572.36036145208 55127.37456588278 56101.53631651648 63896.83300427746 0.8837086308559382 0.9981462487024002 0.9650294953582144 0.8980913704247685 0.8046045958736255 0.9427394024080609 0.8853703337325802 0.862755976688115 0.8780018301182605 1.0 15.963456806461137 -5.8230289237183515 6.031295483828303 0.8874021044070817 0.9537776479054086 0.15066291257937037 0.055095332096832185 0.28405080234035196 19.97944826936074 0.014921271698733729 0.022612116476047713 1.50304186118664e-06 5.8230289237183515 0.06637554349832697 PATS(ph)TPDLASHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PATSTPDLASHR 12 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 PAT(0.016)S(0.707)T(0.277)PDLASHR 136.93 6.4888e-05 6025800.0 11746.0 13413.0 16775.0 14081.0 18179.0 14732.0 16031.0 17362.0 16473.0 12817.0 True False 13734.365805925141 14744.553996571143 17174.979619541773 13292.087221217947 14616.955449043415 13959.427985796196 14512.427625610808 16906.26589655959 16713.88646114579 15140.62064068382 0.9071203969684055 0.9738407920314429 1.1343643056078891 0.8779090062861264 0.9654132281583436 0.9219851891861234 0.9585094277188997 1.1166164385052597 1.1039102595460655 1.0 13.886136724693738 -7.753185298360118 24.95594231231333 1.0826975149782134 0.9650361220187014 0.3374246272036867 0.07073217471936205 190.11851426002596 574821.7817201996 0.03439508458049785 0.019432379539301062 1.7652844744571904e-08 7.753185298360118 -0.11766139295951206 PATS(ph)TPDLASHR ddPTM_PC-9_Lapatinib_30min_R1 2 PATSTPDLASHR 12 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 PAT(0.081)S(0.733)T(0.185)PDLASHR;PAT(0.049)S(0.894)T(0.049)PDLAS(0.008)HR 96.756 0.0041842 25571400.0 35859.0 42427.0 41901.0 36957.0 39147.0 41902.0 35755.0 32256.0 40804.0 26566.0 True False 35347.64408426478 42328.762888207086 38456.0615225374 39674.94106493794 36844.450425963216 40109.949138332784 37606.21894944138 33754.73151631734 36208.2238348312 31157.89770303008 1.134468198758713 1.3585243552581099 1.234231586773506 1.2733510278223805 1.1825075869088602 1.2873124342542572 1.2069562365173376 1.0833443205327271 1.1620881543400787 1.0 14.927310274189994 -8.237406628418348 0.6671432357381104 1.0058247637350282 1.2571913777875041 0.5704186679815808 0.06501732870945824 0.4649073043361904 0.4709226365375635 0.06019803463087521 0.02639685918449393 5.788864332456234e-09 8.237406628418348 0.25136661405247596 PATST(ph)PDLASHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PATSTPDLASHR 12 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 PAT(0.032)S(0.105)T(0.863)PDLASHR 77.42 0.036875 3012200.0 16067.0 17867.0 13125.0 14832.0 15112.0 14309.0 18872.0 13673.0 14810.0 18790.0 True False 18786.825762284963 19640.717681110626 13437.949776839692 14001.011125992793 12150.912082399691 13558.610850445142 17084.30753855199 13314.09823774101 15026.568232232694 22196.478258441846 0.8463876811241391 0.8848573837897368 0.6054090932974433 0.6307762413016073 0.547425223989234 0.6108451391512292 0.7696855032421381 0.5998293099797191 0.6769798369485814 1.0 14.438043173146216 -10.916647640008579 9.340012274175162 1.0000006936221275 0.681335710246614 0.436749266375713 0.10693606853430945 1.6786822438248025e-06 1.0888316119060384e-07 0.11252688769089246 0.027291719670477887 1.2115807374229034e-11 10.916647640008579 -0.3186649833755135 PAVEASTGGEATQETGKEEAGKEEPPPLT(ph)PPAR ddPTM_PC-9_AZD4547_30min_R2 2 PAVEASTGGEATQETGKEEAGKEEPPPLTPPAR 33 2 Q9C0C2;E9PKK0;E9PKE7 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 PAVEAS(0.003)T(0.009)GGEAT(0.02)QET(0.011)GKEEAGKEEPPPLT(0.956)PPAR;PAVEAS(0.003)T(0.009)GGEAT(0.004)QET(0.008)GKEEAGKEEPPPLT(0.975)PPAR 47.647 0.0050969 19454700.0 37540.7 40049.6 32830.2 28309.6 31261.2 38074.6 39233.6 37788.8 39884.9 37081.7 True False 49477.86170493194 52994.8499873861 32394.850097128405 21783.25909895998 26921.121987590748 35693.78924305387 42725.31439444583 31949.40926023697 41993.13438736284 35783.48096979103 1.3827011895992432 1.4809864370692492 0.9053018101977457 0.608751818118247 0.7523337936384104 0.9974934879361547 1.1939954760274776 0.8928535847926353 1.1735340791136026 1.0 15.127006117235005 -5.263191554986658 24.89585901836801 0.9292221425997942 1.4318438476054056 0.5789144851034779 0.16738557593234435 100.9927507081454 1434985.7213989487 0.04783320705794993 0.10852860407369459 5.455171958464959e-06 5.263191554986658 0.5026217050056114 PAVVLPSAAPAGAAAPPSGS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PAVVLPSAAPAGAAAPPSGSR 21 0 P19419 P19419 ELK1 ETS domain-containing protein Elk-1 1 PAVVLPS(0.001)AAPAGAAAPPS(0.233)GS(0.766)R 96.234 0.00095054 0.0 17920.0 19375.0 19491.0 14845.0 12894.0 9663.0 12531.0 8565.9 8146.9 6801.1 True False 20953.50206386673 21298.421955085825 19955.739360029118 14013.282778139363 10367.513260353475 9156.255269260695 11343.972963416441 8341.05420132127 8266.033000079437 8034.085592522025 2.608075532997788 2.651007598787595 2.483884336333626 1.7442287136177217 1.2904409768802265 1.1396760917985693 1.4119805960214311 1.0382082821080432 1.0288704177826167 1.0 12.971918116128773 -5.931961818725624 1.691740448521382 1.1428703592486955 2.6626057131670477 0.9697515890394242 0.11340977768376012 0.05778540384956494 0.3357370773177956 0.03882518086000069 0.06918742449327699 1.1696022128191276e-06 5.931961818725624 1.5197353539183522 up PAYS(ph)PASWSSR ddPTM_PC-9_Lapatinib_30min_R1 1 PAYSPASWSSR 11 0 Q9Y446;Q9Y446-2;E9PK71;E9PQ15 Q9Y446 PKP3 Plakophilin-3 1 PAYS(0.958)PAS(0.041)WS(0.001)SR 105.65 0.0025321 6854500.0 29094.0 32312.0 34554.0 36483.0 26093.0 25358.0 27253.0 24923.0 26869.0 24142.0 True False 28679.114224813835 32237.183549243346 31713.10350229725 39166.08152372026 24558.261040811783 24273.497452385156 28664.026990046856 26081.013565884718 23842.73027688657 28314.91253280708 1.0128625398925308 1.1385231549591306 1.1200141785906228 1.3832315914216748 0.8673260428531202 0.8572690247324855 1.0123297028318654 0.9211052139280298 0.8420555864073811 1.0 14.78927445277313 -6.293429144811395 24.980146708868027 0.9145480062828304 1.158745191900964 0.5909255592659272 0.10062664094792012 467.06535876399465 364720.3414812268 0.03144548704222551 0.035658744011432715 5.088278281846634e-07 6.293429144811395 0.24419718561813353 PCSEETPAIS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 4 PCSEETPAISPSK 13 0 P33316-2;H0YNJ9 P33316-2 DUT Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial 1 PCSEET(0.008)PAIS(0.991)PS(0.001)K;PCSEETPAIS(0.967)PS(0.033)K;PCSEET(0.004)PAIS(0.975)PS(0.021)K;PCSEET(0.154)PAIS(0.844)PS(0.002)K 180.95 8.9625e-05 200617000.0 214591.0 171879.0 180023.0 186123.0 162603.0 189658.0 206486.0 199792.0 175359.0 189182.0 True False 282826.4742299173 227435.52547296204 177635.7773950615 143215.21792168473 140028.3801820856 177798.65527829868 224862.85398361436 168918.73716342586 184628.118737506 182558.7957625194 1.5492349905606877 1.2458206931251905 0.9730332447314016 0.7844881826892934 0.7670316820244626 0.9739254388464913 1.2317284031393696 0.9252840240202004 1.0113351042131022 1.0 17.47800165456139 -4.969034599692216 2.2803536850447674 0.9521421791963817 1.5870045701937365 0.7033229037768691 0.12207279394328775 0.24732624361092212 2.050488969285064 0.03672931615283956 0.27185876698205413 1.0739038523710765e-05 4.969034599692216 0.6348623909973549 PCSEETPAIS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 PCSEETPAISPSK 13 0 P33316-2;H0YNJ9 P33316-2 DUT Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial 1 PCSEETPAIS(0.998)PS(0.002)K;PCSEET(0.001)PAIS(0.965)PS(0.034)K;PCSEETPAIS(1)PSK;PCSEETPAIS(0.986)PS(0.014)K 217.19 1.5888e-14 192908000.0 272852.0 346959.0 241245.0 279699.0 266834.0 192089.0 270907.0 242020.0 205007.0 200660.0 True False 319040.4545273529 381402.79654785176 246997.19572675688 264028.3718263934 214549.79318389625 182015.5146866415 245244.72776316828 235667.23144138668 208004.83953985962 237038.069576314 1.345946054562507 1.6090360389349179 1.0420148804293081 1.1138648416194172 0.9051279972343105 0.7678746077032234 1.0346216884128485 0.9942168018100317 0.8775165943244944 1.0 17.85475925667543 -5.375181815901094 4.264758027418969 0.9569627968129915 1.4755079420129902 0.7827681054049738 0.10798724517565128 0.09571655663781509 2.8690753086401073 0.029598187305059243 0.06575234150663015 4.215199985772907e-06 5.375181815901094 0.5185451451999987 PCSEETPAIS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 4 PCSEETPAISPSK 13 0 P33316-2;H0YNJ9 P33316-2 DUT Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial 1 PCSEET(0.085)PAIS(0.751)PS(0.164)K;PCSEET(0.002)PAIS(0.991)PS(0.006)K;PCSEETPAIS(0.997)PS(0.003)K;PCSEET(0.001)PAIS(0.994)PS(0.006)K 171.76 8.423700000000001e-05 238326000.0 189674.0 235746.0 210855.0 228474.0 240376.0 190565.0 209693.0 223591.0 196651.0 207854.0 True False 186969.21397804836 235200.14462119067 193519.31582383803 245276.74012692118 226237.5562773988 182414.97917871206 220549.87750427081 233979.8541190758 174502.09355316605 243781.28695195468 0.7669547417513508 0.9647998316931717 0.7938235056654596 1.006134405120526 0.9280349575067529 0.7482730994633853 0.9047038854452254 0.9597941541968701 0.7158141452734129 1.0 17.89522786102757 -11.820050000976995 2.4015420900618576 1.6587040799480464 0.8726635900293278 0.14228042743599223 0.09769990518097368 13105468.725798367 4405595.312203706 45849430.06175059 0.023781418843315263 1.5133869998838229e-12 11.820050000976995 -0.7860404899187186 PCSEETPAIS(ph)PSKR ddPTM_PC-9_AZD4547_30min_R2 4 PCSEETPAISPSKR 14 1 P33316-2;H0YNJ9 P33316-2 DUT Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial 1 PCS(0.001)EET(0.004)PAIS(0.498)PS(0.498)KR;PCSEETPAIS(0.5)PS(0.5)KR;PCSEETPAIS(0.771)PS(0.229)KR;PCSEETPAIS(0.986)PS(0.014)KR 169.98 1.7372e-08 3142224000.0 174342.0 137108.0 144950.0 180358.0 178676.0 160737.0 162833.0 151313.0 170773.0 180777.0 True False 229779.1294611251 181425.47970692682 143027.8682913524 138779.2496033227 153869.9215722608 150686.0899802161 177324.82155068067 127931.05267683101 179799.71214001052 174448.05225423616 1.3171779592371191 1.039997164557171 0.8198880207782844 0.7955333854978751 0.8820386331858534 0.8637877467419929 1.016490693127671 0.7333475554681892 1.0306776706109335 1.0 17.412437964093826 -4.861022240330161 2.7663818394905277 0.8835083830063309 1.3599610044444506 0.6526158997143334 0.09432637308120641 0.2033637358685912 2.4164612485992114 0.023089657060942403 0.20595687947067728 1.377138943454862e-05 4.861022240330161 0.4764526214381196 PCSEETPAIS(ph)PSKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PCSEETPAISPSKR 14 1 P33316-2;H0YNJ9 P33316-2 DUT Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial 1 PCSEETPAIS(0.989)PS(0.011)KR;PCSEETPAIS(0.663)PS(0.336)KR 140.03 0.00016462 531424600.0 52569.0 59046.0 47019.0 55752.0 59200.0 52723.0 64408.0 64237.0 52271.0 40295.0 True False 61467.89341492241 64907.69665858046 48140.111280550496 52628.396190422754 47600.18497075582 49958.11306646299 58306.80796646125 62550.846814727476 53035.364487983425 47600.16452495553 1.29133783524417 1.363602359495019 1.0113433800278544 1.1056347539057572 1.000000429532135 1.0495365628467785 1.2249287066201737 1.3140888784519578 1.1141844785048665 1.0 15.538678939614753 -5.250553720097592 24.978454211433707 1.1126193172338106 1.3274701227518073 0.45647772864964553 0.09770777189799505 726.6415465916385 1667358.6693740394 0.02732396935990975 0.07080779933754412 5.616248038249242e-06 5.250553720097592 0.21485080551799673 PCSEETPAIS(ph)PSKR ddPTM_PC-9_Lapatinib_30min_R1 3 PCSEETPAISPSKR 14 1 P33316-2;H0YNJ9 P33316-2 DUT Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial 1 PCSEET(0.008)PAIS(0.629)PS(0.363)KR;PCSEETPAIS(0.942)PS(0.058)KR;PCSEETPAIS(0.719)PS(0.281)KR 122.1 9.2104e-05 2437313000.0 159429.0 118186.0 102323.0 126243.0 111915.0 106935.0 96305.0 93472.0 120687.0 108446.0 True False 157155.51322430247 117912.34757832592 93910.39791820224 135527.33135430233 105332.37973335563 102361.63932766009 101291.20167601599 97815.05035631242 107093.95916954901 127190.74660478794 1.2355892029836275 0.9270513046417423 0.7383430039136755 1.0655439563965934 0.8281449912441234 0.8047884147242422 0.7963724121437228 0.769042190311589 0.8419948937190812 1.0 16.95663418976831 -4.788118228368618 3.57958439520604 0.8488226370969456 1.2772721481534712 0.5773320783423663 0.09694700130099043 0.18684502247974988 4.0427182086870594 0.024124957380622796 0.21429184334408205 1.6288525483161654e-05 4.788118228368618 0.4284495110565256 PCSEETPAISPS(ph)KR ddPTM_PC-9_AZD4547_30min_R2 1 PCSEETPAISPSKR 14 1 P33316-2;H0YNJ9 P33316-2 DUT Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial 1 PCSEETPAIS(0.043)PS(0.957)KR 59.728 0.026813999999999998 225090000.0 131100.0 115370.0 108040.0 99728.0 97091.0 93269.0 106690.0 74132.0 93607.0 108100.0 True False 172787.07295059937 152661.0963166856 106607.31900791812 76737.25038224069 83611.59056265204 87436.8746857586 116185.20331408338 62676.60278389064 98554.87491752199 104315.45190307908 1.6563900150779025 1.4634562141237246 1.0219705428393144 0.7356268796451969 0.8015264185437908 0.8381967684614682 1.1137870870945625 0.6008371879759897 0.9447773375807322 1.0 16.67059334977114 -5.250281822779791 2.416619510243507 0.8520832329216718 1.636472008581628 0.807497556840279 0.13550217719192761 0.12066189545511587 1.3295030162276715 0.036219311259136355 0.1260320610313403 5.619765285086245e-06 5.250281822779791 0.7843887756599562 PCSEETPAISPS(ph)KR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 PCSEETPAISPSKR 14 1 P33316-2;H0YNJ9 P33316-2 DUT Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial 1 PCSEETPAIS(0.234)PS(0.765)KR;PCSEETPAIS(0.233)PS(0.767)KR;PCSEETPAIS(0.065)PS(0.934)KR;PCSEETPAIS(0.011)PS(0.989)KR;PCSEETPAIS(0.033)PS(0.966)KR 99.81299999999999 0.00096837 2921420000.0 389733.0 419153.0 305412.0 374569.0 321809.0 283133.0 380861.0 345419.0 281751.0 301994.0 True False 455707.09932237654 460763.7397543263 312694.1803614596 353583.11329908343 258752.83657523518 268285.00705283973 344783.08888514445 336352.1172516824 285871.07535447576 356743.12161681126 1.277409630932886 1.2915840890388541 0.8765247636570664 0.99114206237977 0.7253197634267762 0.7520397473592018 0.966474384488586 0.9428412122630034 0.8013359138050562 1.0 18.444526087725848 -5.262040528188333 24.833417970062285 0.8766018013270996 1.2844968996392703 0.7529738081697224 0.09218389614900221 21.773645841947808 899519.4500321863 0.024685929661849782 0.05687401797437123 5.469649179636452e-06 5.262040528188333 0.40789509831217063 PCSEETPAISPS(ph)KR ddPTM_PC-9_Lapatinib_30min_R1 6 PCSEETPAISPSKR 14 1 P33316-2;H0YNJ9 P33316-2 DUT Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial 1 PCSEETPAIS(0.308)PS(0.692)KR;PCSEETPAIS(0.003)PS(0.997)KR;PCSEETPAIS(0.039)PS(0.961)KR;PCS(0.001)EET(0.012)PAIS(0.279)PS(0.708)KR;PCSEETPAIS(0.065)PS(0.935)KR;PCSEETPAIS(0.123)PS(0.877)KR 152.0 8.5135e-09 2094659000.0 383570.3 427172.0 268687.9 371700.0 307366.3 272156.5 286172.5 236555.3 279422.7 299597.2 True False 378100.517183822 426182.9094793696 246597.41802728784 399036.0579548518 289287.61853939656 260517.00092278785 300989.11179720325 247546.5228255795 247951.1730745242 351382.1768318244 1.07603783604763 1.212875716469096 0.7017926186543952 1.1356183786915155 0.8232848380293716 0.7414064175698767 0.8565861664100856 0.7044936799513828 0.7056452757795866 1.0 18.42268148977724 -5.2781024472022295 0.6476980187855053 0.7831890939791923 1.2448427912932556 0.3427654245627807 0.1500173051945986 2.0705990465926267 1.0050271078862072 0.07444339581022319 0.64658059990025 5.271055060457586e-06 5.2781024472022295 0.46165369731406325 PDERPSS(ph)PIPLLPPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PDERPSSPIPLLPPPK 16 1 O15047 O15047 SETD1A Histone-lysine N-methyltransferase SETD1A 1 PDERPS(0.434)S(0.566)PIPLLPPPK 74.36399999999999 0.024523 0.0 20238.0 32369.0 20912.0 27557.0 27573.0 21653.0 23227.0 20704.0 24407.0 22894.0 True False 23663.893681279824 35582.38040073149 21410.62138920163 26013.07063099943 22170.26858443667 20517.478562072018 21026.7704110824 20160.5419377013 24763.906201492457 27044.500971195714 0.8749983483327545 1.315697429160524 0.7916811410942817 0.9618617351714188 0.8197699269086 0.7586562082962658 0.7774878313886207 0.7454580862547135 0.9156725142707477 1.0 14.723047656481665 -5.290271859813649 24.988177923427646 0.8348212716565564 1.0953479811814575 0.3712763998346702 0.12893010860425724 566.4356255487248 490910.46676328185 0.03171358595794445 0.06603415310064908 5.125404433022739e-06 5.290271859813649 0.2605267095249011 PDLDVKDNSFS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 PDLDVKDNSFSR 12 1 H0Y332;Q5JRH0;Q5T5C0-2;Q5T5C0 H0Y332 STXBP5 Syntaxin-binding protein 5 1 PDLDVKDNS(0.111)FS(0.889)R 58.04 0.029462000000000002 3983300.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PDSS(ph)TSSPASPAMERR ddPTM_PC-9_AZD4547_30min_R2 1 PDSSTSSPASPAMERR 16 1 Q4TT46;A6ZJ82;O14994 Q4TT46 SYN3 Synapsin-3 1 PDS(0.001)S(0.84)T(0.052)S(0.052)S(0.052)PAS(0.002)PAMERR 89.26 0.0055799 3888700.0 5200.8 4218.4 4276.9 6342.6 6335.6 5447.2 5625.4 4490.7 3467.2 5134.1 True False 6854.54621663981 5581.915304691923 4220.185511523185 4880.411562193165 5456.011300416485 5106.585722890408 6126.049702156203 3796.7655010200415 3650.469113570908 4954.356721698419 1.3835390953217395 1.1266680253856183 0.851813009959535 0.9850747203604862 1.1012552399630384 1.0307262899591538 1.2364975003366556 0.7663488348328822 0.7368199987665561 1.0 12.274482033362908 -4.881202927888789 3.179801618661962 0.9731408588537996 1.4028881840510663 0.4481251970480392 0.14319124806168831 0.2897871448377257 4.934767240007244 0.039182264115919324 0.2737410227894003 1.3146104254599104e-05 4.881202927888789 0.42974732519726666 PDSS(ph)TSSPASPAMERR ddPTM_PC-9_Lapatinib_30min_R1 1 PDSSTSSPASPAMERR 16 1 Q4TT46;A6ZJ82;O14994 Q4TT46 SYN3 Synapsin-3 1 PDS(0.005)S(0.364)T(0.364)S(0.089)S(0.089)PAS(0.089)PAMERR 74.133 0.033969 0.0 4346.1 7875.3 8257.3 4833.0 4892.4 7287.0 6636.9 6147.8 6114.8 5953.1 True False 4284.12381702287 7857.0652267069945 7578.416668099758 5188.434942415373 4604.63865082848 6975.351996826663 6980.526207398891 6433.449231647313 5426.086832301387 6982.085402992868 0.6135879998240185 1.1253178346026915 1.085408761235042 0.7431067715372478 0.6594933154003966 0.9990356167566614 0.9997766862614844 0.9214223058471354 0.777144150940276 1.0 12.76944228831883 -9.388100616254414 15.821302919879546 1.000006002323034 0.8913659299663387 0.040050714252022224 0.1681035496569475 0.0 0.0 0.16639146758877713 0.040355858592356804 4.091658542311948e-10 9.388100616254414 -0.10864007235669526 PDSSTS(ph)SPASPAMERR ddPTM_PC-9_AZD4547_30min_R2 1 PDSSTSSPASPAMERR 16 1 Q4TT46;A6ZJ82;O14994 Q4TT46 SYN3 Synapsin-3 1 PDSS(0.071)T(0.097)S(0.413)S(0.413)PAS(0.007)PAMERR 88.78 0.005751399999999999 3137100.0 5470.8 4785.8 6333.7 7039.4 6390.0 7121.1 5852.0 8076.3 4346.0 5844.5 True False 7210.400600290926 6332.716258580175 6249.710999633936 5416.575087645849 5502.85879942884 6675.816491275305 6372.816663173837 6828.293409911189 4575.720687465151 5639.885833927349 1.2784657017197005 1.1228447605242342 1.1081272181146145 0.9604050945609306 0.975703934701265 1.1836793665425287 1.1299549052637665 1.2107148284518179 0.8113144170294022 1.0 12.461450243652488 -4.700695500105145 1.6745301879821166 1.056400100211061 1.3875429094234042 0.2815754069975277 0.11247357544955185 1.730816970130333 4.1080854819862695 0.03141005444143363 0.9911767497206522 1.992069562973137e-05 4.700695500105145 0.3311428092123432 PECT(ph)LVPR ddPTM_PC-9_Lapatinib_30min_R1 2 PECTLVPR 8 0 Q8WWW8-3;Q8WWW8;Q8WWW8-2 Q8WWW8-3 GAB3 GRB2-associated-binding protein 3 1 PECT(1)LVPR;PECT(1)LVPR 89.08 0.025658999999999998 24501000.0 74686.0 85189.0 62356.0 65467.0 90736.0 75982.0 77504.0 76907.0 63757.0 62487.0 True False 73620.96394426493 84991.75010449652 57229.330381120744 70281.66157151002 85399.0868738397 72732.42698269298 81516.77789001542 80480.3799828069 56576.015269025884 73287.79469130619 1.004546040092516 1.1596985618476894 0.7808848747895208 0.9589818040990559 1.1652566055991616 0.9924220982367874 1.112283133001482 1.0981416526694032 0.7719704966881374 1.0 16.161285332280954 -8.24943219116054 24.95041971849566 0.8859852325569071 1.0328723792816905 0.1984716019870788 0.11898381392381834 1052.980291285562 2188058.9690202666 0.0821763374561157 0.03052606770967239 5.63077026913506e-09 8.24943219116054 0.14688714672478342 PEGET(ph)GDLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PEGETGDLGK 10 0 Q12873;Q12873-3 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 PEGET(1)GDLGK 86.833 0.026929 1488600.0 496.76 425.2 986.84 779.44 2510.5 2387.8 1913.9 1046.3 979.63 544.14 True False 580.8516565427699 467.411045951096 1010.3700082115415 735.7705037785751 2018.5855467750423 2262.579564518337 1732.6015365639387 1018.835733646487 993.9552354721205 642.7882745901298 0.9036438272200072 0.7271617489431305 1.571855069782967 1.1446545197915048 3.1403583832673077 3.5199452976348358 2.6954467047002715 1.5850253869303101 1.546318243135207 1.0 9.328199802134092 -2.24456115359129 6.3609701303840165 1.8579884077193882 1.0238597662549531 0.0 0.937867853195212 0.0 0.0 0.24078015515565762 0.0 0.005694280365531649 2.24456115359129 -0.8341286414644351 PES(ph)GLT(ph)LQESNTPGLRQMNFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PESGLTLQESNTPGLRQMNFK 21 1 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 2 PES(0.999)GLT(0.999)LQES(0.001)NT(0.001)PGLRQMNFK 59.872 0.038408 0.0 0.0 1041.9 2436.8 2547.9 2610.4 943.09 844.74 1319.4 1037.6 665.47 True False 0.0 1145.332946322782 2494.9025536154636 2405.1494234032534 2098.9108589131915 893.6327001849401 764.720111812018 1284.767148019855 1052.7729370536558 786.1144431423787 0.0 1.4569544629462337 3.173714177852339 3.059541068586676 2.669981294991985 1.136771761389821 0.9727847115429658 1.634325840502541 1.339210780615286 1.0 9.618595546196547 -6.778379363725965 24.922278254076414 1.2410241060201384 2.1539323936435415 0.1917546706556904 0.8693004553200087 426.9882782688432 628185.4115538242 0.3368119006477091 0.29780111635903855 1.6657914792304847e-07 6.778379363725965 0.9129082876234031 PESDGGS(ph)KITGY(ph)VVEMQT(ph)KGSEK ddPTM_PC-9_Lapatinib_30min_R1 1 PESDGGSKITGYVVEMQTKGSEK 23 2 A0A0A0MRA3;A0A0A0MTS7;Q8WZ42-3;Q8WZ42-10;Q8WZ42-9;Q8WZ42-5;Q8WZ42-11;Q8WZ42-4;Q8WZ42-7;Q8WZ42-2;Q8WZ42;Q8WZ42-8;Q8WZ42-13;Q8WZ42-12 A0A0A0MRA3 TTN Titin 3 PES(0.171)DGGS(0.713)KIT(0.316)GY(0.8)VVEMQT(0.505)KGS(0.495)EK 52.86600000000001 0.0328 0.0 7833.8 9507.1 21927.0 11782.0 15732.0 16759.0 14095.0 12528.0 17194.0 10681.0 True False 7722.088575457025 9485.086894064483 20124.24670066771 12648.487583599828 14806.674690302038 16042.25663713711 14824.770132635334 13110.096615712548 15257.43065915321 12527.196618462112 0.6164259100137777 0.7571595771144614 1.606444547298743 1.009682211338406 1.1819623449096757 1.2805943041952925 1.1834068374712938 1.046530761430804 1.2179445349063478 1.0 13.612775978794483 -5.06412498914978 9.464560891482877 1.1886595813531537 0.6510477586001462 0.6032896367475293 0.16521860127033763 0.2517853193705064 36.092382420888775 0.03974369211783396 0.10607746102150957 8.627302198706526e-06 5.06412498914978 -0.5376118227530076 PETVGS(ph)ADSITGNFGTER ddPTM_PC-9_Lapatinib_30min_R1 1 PETVGSADSITGNFGTER 18 0 A0A0C4DGB3;Q86UD5-2 A0A0C4DGB3 SLC9B2 1 PETVGS(0.999)ADSITGNFGTER 79.771 0.0038775 20228000.0 835.25 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1198.8 0.0 True False 823.339181833909 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1063.7785200763562 0.0 0.0 PEVGLSRPS(ph)SGLPAAFAGPS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 PEVGLSRPSSGLPAAFAGPSR 21 1 Q6ZQT7 Q6ZQT7 Putative uncharacterized protein FLJ44672 2 PEVGLS(0.006)RPS(0.834)S(0.184)GLPAAFAGPS(0.976)R 43.534 0.039092 11134000.0 25428.0 18803.0 23045.0 27297.0 27512.0 32548.0 26466.0 30370.0 24221.0 30479.0 True False 33513.57506474331 24880.702037294268 22739.4082426645 21004.098384445926 23692.433691687987 30512.768414715236 28821.42272856438 25677.014333172734 25501.27261184847 29411.939487085576 1.1394547809218332 0.8459388422249094 0.7731352858470655 0.7141351012798245 0.8055379585590079 1.0374279611214698 0.9799225495217517 0.8730132993931664 0.8670381163760306 1.0 14.844114301351516 -6.740663574881633 24.999324199448655 0.9453213912830184 0.8426563887890469 0.13987557870328715 0.11612756715384787 498.0476316535068 599294.6943965333 0.04068387590488812 0.040642540920665264 1.8169225922411774e-07 6.740663574881633 -0.10266500249397148 PFGSVSS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PFGSVSSPK 9 0 Q96HC4;A0A0D9SFR4 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 1 PFGSVS(0.023)S(0.977)PK 92.538 0.0069509 9400500.0 137880.0 181550.0 99552.0 117850.0 129030.0 102050.0 152500.0 113920.0 91368.0 116200.0 True False 161220.36074586748 199573.08417784958 101925.69723306256 111247.24657485502 103747.4977496052 96698.3183512422 138054.0959956116 110929.72070821734 92704.08414872614 137266.1401613062 1.174509318586593 1.453913426452615 0.7425407104278312 0.8104492953915986 0.7558127417853225 0.7044586395276261 1.0057403510682201 0.8081360820509704 0.675360172871375 1.0 17.066616270018052 -5.2666426946255 24.987368985336865 0.806860385193582 1.31421138612915 0.7276795639543132 0.1226480124254053 180.87927549891086 868622.5835449096 0.030754620518625916 0.06726392982041142 5.411993986649305e-06 5.2666426946255 0.507351000935568 PFS(ph)GTTPSR ddPTM_PC-9_AZD4547_30min_R2 2 PFSGTTPSR 9 0 A0A1B0GTR0 A0A1B0GTR0 1 PFS(0.464)GT(0.268)T(0.268)PSR;PFS(0.333)GT(0.333)T(0.333)PSR 87.75399999999999 0.010646 39201000.0 158032.0 143855.0 176083.0 306130.0 262490.0 234960.0 193277.0 257120.0 178036.0 190910.0 True False 208282.8887301993 190353.3155121504 173748.02436941155 235556.4581613522 226047.79440721078 220267.91405682376 210478.2785728382 217388.01202981157 187446.61949230233 184226.29900848144 1.1305817348076366 1.033258099069704 0.9431228076802026 1.2786255785907505 1.22701153756991 1.1956377305646413 1.1424985450266694 1.1800053152009715 1.0174802430551604 1.0 17.491119500800067 -4.406073923139499 21.02129080560175 1.1230488786702943 3.28901534917018 0.0 0.10517858625202592 10365.681613190287 2596332.249215921 0.026680382028492922 424248.2908606889 3.9257810729700835e-05 4.406073923139499 2.1659664704998853 PFS(ph)GTTPSR ddPTM_PC-9_Lapatinib_30min_R1 1 PFSGTTPSR 9 0 A0A1B0GTR0 A0A1B0GTR0 1 PFS(0.333)GT(0.333)T(0.333)PSR 82.305 0.015968 14275000.0 67071.0 52803.0 67891.0 51001.0 59682.0 55788.0 50958.0 56268.0 69039.0 51464.0 True False 66114.55524068512 52680.73789770663 62309.26404683858 54751.78367434854 56171.62209932656 53402.07728817977 53596.355900591065 58882.416696433094 61263.10080710008 60359.48382853049 1.0953465975372432 0.8727831080756477 1.0323027980797026 0.9070949617443328 0.9306179996319911 0.8847338297306293 0.88795252213965 0.9755288309573115 1.0149705882365827 1.0 15.881292848084632 -7.995754013660029 24.433513979754235 1.0034067848543227 0.9401253354295908 0.12450531773528362 0.06651484384685724 165.375085270088 951651.7211101062 0.03530305172107926 0.01684602222512089 1.0098246933541178e-08 7.995754013660029 -0.0632814494247319 PFSAPKPQTS(ph)PSPK ddPTM_PC-9_AZD4547_30min_R2 2 PFSAPKPQTSPSPK 14 1 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 1 PFSAPKPQT(0.032)S(0.551)PS(0.417)PK;PFS(0.002)APKPQT(0.415)S(0.575)PS(0.008)PK 79.61399999999999 0.0059294 60275000.0 246880.0 240980.0 233320.0 238180.0 207735.0 261440.0 270820.0 253260.0 287700.0 264580.0 True False 325382.70457699423 318872.0723792576 230226.02435141994 183271.28084431746 178894.58101711224 245092.1154707862 294922.4553521423 214124.48633583522 302907.23464880924 255317.13473188484 1.2744256468281576 1.2489254695503043 0.9017257090605622 0.7178181794840185 0.7006759699264763 0.9599516919542583 1.1551220628488097 0.838660854316311 1.1863960284800312 1.0 17.96193083694954 -5.2557186837713115 13.750242951351858 0.9197562946572251 1.2617153493971613 0.4272987550116152 0.15183885456250876 0.9708997269224784 2313.1156645767423 0.04157213121862962 0.1008226363474606 5.5498509067128456e-06 5.2557186837713115 0.34195905473993626 PFSAPKPQTS(ph)PSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PFSAPKPQTSPSPK 14 1 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 1 PFS(0.001)APKPQT(0.117)S(0.704)PS(0.178)PK 82.55 0.0042991999999999995 26729000.0 73944.0 113810.0 83519.0 105580.0 106190.0 58069.0 90018.0 59475.0 64109.0 72183.0 True False 86461.25873942848 125108.30465591287 85510.40970757144 99664.69489497841 85382.83179129307 55023.759415367866 81490.84336611774 57913.844268971414 65046.47284268774 85269.20649968655 1.0139798678640959 1.4672155376087939 1.002828725841207 1.1688239985597237 1.001332547777455 0.6452946107287879 0.9556890079235967 0.679188263223539 0.7628366149147506 1.0 16.37973721076473 -6.507119968794919 3.762629369280094 0.7974416374412551 1.1700018377182129 0.5283579134024063 0.1573230307916765 0.1670672906457967 5.170047756833024 0.04999713780596028 0.05367593691246509 3.1108568804049065e-07 6.507119968794919 0.3725602002769578 PFSAPKPQTS(ph)PSPK ddPTM_PC-9_Lapatinib_30min_R1 1 PFSAPKPQTSPSPK 14 1 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 1 PFSAPKPQT(0.057)S(0.886)PS(0.057)PK 104.55 0.0004982 25526000.0 47216.0 86907.0 81320.0 81899.0 104450.0 87433.0 95567.0 111800.0 88630.0 88879.0 True False 46542.69118164604 86705.77218105008 74634.18350427756 87922.1256670551 98306.4563566009 83693.69440627772 100514.99164707772 116994.63614596582 78647.55608472426 104241.61672617681 0.4464885776273498 0.8317769323245426 0.7159730043359512 0.8434455299941293 0.9430634274872534 0.8028817763458654 0.9642501220132815 1.122340959592835 0.7544736790807518 1.0 16.66957183898073 -4.287345884049566 0.5652939389738032 0.948727196666454 5.210551740061306e-16 0.589517282512963 0.11286347030417251 4.737149072792474 0.7653284829259291 0.057073490576541576 3.325016169381675 5.1600524483375656e-05 4.287345884049566 -0.9487271966664534 PGACISS(ph)AGTPPMHGWTSR ddPTM_PC-9_AZD4547_30min_R2 1 PGACISSAGTPPMHGWTSR 19 0 H0YKS8 H0YKS8 MFGE8 1 PGACIS(0.013)S(0.493)AGT(0.493)PPMHGWTSR 62.708999999999996 0.012884999999999999 17707000.0 31508.0 38559.0 39348.0 40283.0 44330.0 37223.0 55254.0 61825.0 39157.0 46465.0 True False 41526.88859288705 51022.44268765785 38826.21981047354 30996.376716145918 38175.5446914993 34895.43992567734 60171.4989588187 52271.366847165074 41226.75907940012 44838.27449284529 0.9261482307824619 1.1379216364759832 0.8659169035746219 0.6912928088053861 0.8514053032435684 0.7782511776015266 1.3419673178641183 1.1657756110910527 0.9194546299050503 1.0 15.452443139661705 -7.242224537883113 24.998416508095016 1.1206140535351525 0.8772429451797805 0.36615077620882364 0.14885145065885788 924.6984245311718 1203029.4999564346 0.06078860007760486 0.04701498575438408 5.72499961909695e-08 7.242224537883113 -0.243371108355372 PGAGQPGEFHT(ph)TPPGTPR ddPTM_PC-9_AZD4547_30min_R2 1 PGAGQPGEFHTTPPGTPR 18 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 PGAGQPGEFHT(0.491)T(0.491)PPGT(0.017)PR 76.678 0.011064000000000001 4843600.0 24529.0 27952.0 24049.0 28301.0 27757.0 29560.0 30168.0 28375.0 27780.0 33174.0 True False 32328.711765104945 36986.93736884805 23730.094546662545 21776.641696091312 23903.41967069582 27711.608527067172 32852.8935568401 23990.2957426334 29248.394086005974 32012.58835737975 1.00987497181409 1.1553872794019662 0.7412738477047305 0.6802524510977638 0.7466881279278202 0.8656472328229876 1.0262492114064445 0.7494019376006814 0.9136528967756349 1.0 14.966351709334791 -5.25925191080712 24.998937152922675 0.829919144128088 1.082631136771079 0.4170273923782971 0.11402469038539254 175.42677396357158 2004787.835747028 0.030411709712722685 0.0728619668938036 5.504882952088563e-06 5.25925191080712 0.25271199264299105 PGGARPCS(ph)PGLER ddPTM_PC-9_Lapatinib_30min_R1 1 PGGARPCSPGLER 13 1 P23677 P23677 ITPKA Inositol-trisphosphate 3-kinase A 1 PGGARPCS(1)PGLER 56.46 0.034579 4315900.0 13830.0 19642.0 21046.0 18058.0 18760.0 19809.0 16287.0 17762.0 19232.0 15243.0 True False 13632.781663888616 19596.520155800874 19315.679119909368 19386.045559722075 17656.57368357909 18961.815247034378 17130.261167096945 18587.287363368952 17065.88963806181 17877.732239979214 0.7625565413381796 1.0961412718766426 1.0804322864123972 1.084368268832771 0.9876293842288588 1.0606387316077412 0.9581898272751435 1.0396893249023493 0.9545891732228814 1.0 14.125876124256862 -4.752856971556363 24.99711647510056 1.031124458508305 0.762556036406291 0.7230237250861689 0.049472707043400725 176.29951737395382 513451.10572272685 0.012555978682982671 0.14358137756579495 1.766619534822481e-05 4.752856971556363 -0.26856842210201404 PGHLQEGFGCVVTNR ddPTM_PC-9_AZD4547_30min_R2 1 PGHLQEGFGCVVTNR 15 0 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 92.26899999999999 0.0070593999999999995 0.0 23969.0 27187.0 30377.0 38167.0 34091.0 34286.0 40189.0 51422.0 46209.0 37677.0 False True 31590.64341382854 35974.66607923841 29974.181132020793 29368.187824271812 29358.053103494294 32142.090999967044 43765.743143590786 43475.91146000683 48651.51340245682 36357.93969798628 0.8688788109623885 0.9894583240433423 0.824419133234905 0.8077517061809307 0.807472957691283 0.8840459956466473 1.20374651333763 1.195774893218572 1.3381262471578232 1.0 15.149982827934199 -7.248041467667795 5.622832019311858 1.2021575674981788 0.8611403434702332 0.74715398453519 0.09122435872395199 0.08113113576841895 9.533175428422306 0.03624015585673809 0.02652558262863004 5.648830356042575e-08 7.248041467667795 -0.34101722402794565 PGHLQEGFGCVVTNR ddPTM_PC-9_Lapatinib_30min_R1 2 PGHLQEGFGCVVTNR 15 0 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 ; 116.87 0.00011536 13804500.0 162402.0 154660.0 162197.0 171985.0 177906.0 157907.0 157108.0 139688.0 139227.0 194053.0 False True 160086.11769912066 154301.89427228202 148861.7887585262 184633.35062514176 167441.91885665347 151153.68570919562 165242.28350465224 146178.4144361151 123545.78913469368 227594.8024906311 0.7033821332792105 0.6779675659712565 0.6540649748126567 0.8112371135221428 0.7357018570911618 0.6641350507791928 0.7260371576870892 0.6422748359648174 0.5428322078654649 1.0 17.796108086094442 -11.902878543685105 2.4621345790337372 3.692290962808048 0.6877740378919944 0.6701954496874719 0.06642098451285011 1964264.0967248406 703617.8204631314 30284150.02944362 0.017150351003855112 1.2506087309311594e-12 11.902878543685105 -3.0045169249160533 PGLVTVTSSQST(ph)PAKAPR ddPTM_PC-9_AZD4547_30min_R2 1 PGLVTVTSSQSTPAKAPR 18 1 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 PGLVTVT(0.005)S(0.027)S(0.019)QS(0.146)T(0.802)PAKAPR 110.67 0.00015862 9634700.0 15305.0 10530.0 17526.0 27608.0 20764.0 18265.0 13687.0 22866.0 16440.0 19933.0 True False 20171.671636223702 13933.616574626849 17293.593788715036 21243.40213934803 17881.277012729337 17122.88666261442 14905.116484767641 19332.585108407216 17308.984837074804 19235.151737133 1.0486879392421309 0.7243829820031175 0.8990619894788855 1.1044052279732293 0.9296145544934776 0.890187241390932 0.7748894673907702 1.0050653809549173 0.8998621416466511 1.0 14.231457589976587 -9.310038858285592 1.199208511255275 1.000069232112458 0.9153229688750567 0.04436979188232715 0.10919442878126413 22.102114125587434 30.225402541174407 0.11394962354327615 0.03211949584759119 4.897349986094436e-10 9.310038858285592 -0.08474626323740131 PGLVTVTSSQST(ph)PAKAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PGLVTVTSSQSTPAKAPR 18 1 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 PGLVT(0.008)VT(0.004)S(0.016)S(0.011)QS(0.206)T(0.755)PAKAPR 87.208 0.0012005999999999998 4916100.0 17960.0 13582.0 15956.0 23796.0 18468.0 14654.0 15687.0 21871.0 12950.0 13106.0 True False 21000.273273830717 14930.331199689057 16336.451553466972 22462.787267672913 14849.327973647263 13885.51844310735 14201.013795955125 21296.90942424001 13139.36925100697 15482.01405296109 1.3564303198532626 0.964366208983868 1.0551890404945383 1.4508956774507435 0.9591341231735402 0.896880625195635 0.9172588106028129 1.375590369017057 0.8486860434346353 1.0 13.91830554322894 PGLVTVTSSQST(ph)PAKAPR ddPTM_PC-9_Lapatinib_30min_R1 1 PGLVTVTSSQSTPAKAPR 18 1 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 PGLVTVT(0.006)S(0.081)S(0.045)QS(0.248)T(0.619)PAKAPR 92.913 0.00078504 6389300.0 12339.0 21343.0 20383.0 16331.0 15822.0 14436.0 9930.4 14963.0 13287.0 18516.0 True False 12163.043597304531 21293.58159481 18707.18842065534 17532.03621861898 14891.381067248842 13818.605931959615 10444.547522179628 15658.235605117085 11790.478141687145 21716.465928980837 0.5600839306488092 0.9805270187352862 0.8614287647830586 0.8073153466109008 0.6857184366898367 0.6363192785212142 0.4809506093825919 0.7210305606963892 0.5429280335136223 1.0 14.406501722029883 -6.318367470594493 3.269071582975523 0.6478289602323272 0.8213793059211799 0.10783513788862642 0.16238732773639739 0.41384190533522974 8.8471110030481 0.049880570202815167 0.05939255991370902 4.804326668171447e-07 6.318367470594493 0.17355034568885275 PGMYPDPHS(ph)PFAVSPIPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PGMYPDPHSPFAVSPIPGR 19 0 P41162 P41162 ETV3 ETS translocation variant 3 1 PGMYPDPHS(0.99)PFAVS(0.01)PIPGR 70.89699999999999 0.0046444 3592100.0 11662.0 9546.5 8890.8 12620.0 18832.0 17788.0 15275.0 11106.0 16648.0 15895.0 True False 13636.146265000767 10494.213429379446 9102.790390546761 11912.942314592034 15142.004786643141 16855.165966015666 13828.041418576813 10814.47926777968 16891.44550507831 18776.63767524923 0.7262293974482719 0.5588973708116329 0.48479341977961116 0.6344555676384648 0.8064279158245065 0.89766689103415 0.7364492864877774 0.5759539836056476 0.8995990548054341 1.0 14.196651122864136 -6.178732334761443 4.227307031195787 0.7980696847338119 0.583928259547649 0.43575695542896786 0.12062919011674021 0.2389504495346309 7.881617019072285 0.03700699199088283 0.04824560106724477 6.626247680921891e-07 6.178732334761443 -0.21414142518616286 PGPS(ph)PLPHR ddPTM_PC-9_AZD4547_30min_R2 1 PGPSPLPHR 9 0 P08621;P08621-4 P08621 SNRNP70 U1 small nuclear ribonucleoprotein 70 kDa 1 PGPS(1)PLPHR 66.56 0.027268 3912700.0 13179.0 13743.0 14402.0 16637.0 18056.0 15865.0 13824.0 19693.0 14535.0 15714.0 True False 17369.64785977081 18185.155990987354 14211.020069900373 12801.596689087693 15549.23606924681 14872.959042013568 15054.309219363478 16649.89935012086 15303.290426209389 15163.857642969357 1.1454636589670277 1.1992433864227687 0.937163906737758 0.8442176780143467 1.0254142735543375 0.9808163194481938 0.9927756889978013 1.0979989223151603 1.009195073346305 1.0 13.888349197333518 -5.25735582647642 24.980173308225844 0.9858560154050839 1.1723535393214832 0.5887293318904335 0.06231966726212743 248.98839102294767 1523112.2546704586 0.017576606550211787 0.04305538047912732 5.528969236721192e-06 5.25735582647642 0.1864975239163993 PGPS(ph)PLPHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PGPSPLPHR 9 0 P08621;P08621-4 P08621 SNRNP70 U1 small nuclear ribonucleoprotein 70 kDa 1 PGPS(1)PLPHR;PGPS(1)PLPHR 86.014 0.0092866 1984800.0 43491.0 50252.0 43522.0 41819.0 50927.0 30594.0 35095.0 36599.0 35721.0 34157.0 True False 50853.16731359528 55240.68645610178 44559.729538104126 39476.017009027295 40948.21993252843 28989.59678234107 31770.547534203182 35638.3150298459 36243.35204750735 40349.393713336765 1.2603204815141171 1.3690586492714254 1.1043469414851632 0.9783546511128669 1.0148410214895927 0.7184642472771302 0.7873859954357133 0.8832428879362888 0.8982378348730371 1.0 15.30025937539863 -5.677955888087698 1.255179412233986 0.8584092404945545 1.339015887691526 0.7844879602806651 0.08856785073062931 0.21997419672550164 0.6666804488731762 0.030915712959390176 0.08989202671451421 2.099153086780025e-06 5.677955888087698 0.48060664719697144 PGPTPSGTNVGSS(ph)GRSPSK ddPTM_PC-9_AZD4547_30min_R2 2 PGPTPSGTNVGSSGRSPSK 19 1 P60468 P60468 SEC61B Protein transport protein Sec61 subunit beta 1 PGPTPS(0.005)GT(0.007)NVGS(0.014)S(0.422)GRS(0.422)PS(0.131)K;PGPT(0.032)PS(0.037)GT(0.004)NVGS(0.038)S(0.439)GRS(0.439)PS(0.012)K 61.821000000000005 0.007843000000000001 540920000.0 47507.0 30955.3 56628.0 41702.0 48234.0 28732.6 43123.0 37190.0 33300.0 36444.0 True False 62613.23779301399 40960.99536111553 55877.07571992211 32088.24818947738 41537.54167944454 26935.945979865042 46960.863459679626 31443.14004118187 35060.170016702614 35168.106652690265 1.780398314056644 1.1647199482654584 1.588856524798092 0.9124246723422262 1.1811139590099893 0.765919708043325 1.3353253253992634 0.8940811159299801 0.9969308374473042 1.0 15.10198004615038 -1.5228788261292003 0.47838635316513184 0.9936803410503013 20.810972369270186 0.5249691657291169 0.2112535500935493 76.46836764160798 0.8605300337970023 0.11532623285843795 1505.540220065097 0.029999994415158934 1.5228788261292003 19.817292028219885 PGPTPSGTNVGSS(ph)GRSPSK ddPTM_PC-9_Lapatinib_30min_R1 1 PGPTPSGTNVGSSGRSPSK 19 1 P60468 P60468 SEC61B Protein transport protein Sec61 subunit beta 1 PGPT(0.001)PS(0.002)GT(0.002)NVGS(0.026)S(0.686)GRS(0.158)PS(0.126)K 50.722 0.02692 227500000.0 33206.0 21003.0 11355.0 9847.1 7183.0 7483.2 6488.1 8915.0 13395.0 4676.7 True False 32732.476350765395 20954.368843920478 10421.435731567555 10571.28858296264 6760.510062321351 7163.160980191202 6824.022071482889 9329.22344580758 11886.31404439672 5485.061363688956 5.9675679414370855 3.8202615166054774 1.8999670269064521 1.9272872046508815 1.2325313454241098 1.3059399895890402 1.2441104335965754 1.7008421286891946 2.16703392291725 1.0 12.42129204541718 -4.836277384774882 1.345418286897507 1.4791854083988636 7.654348462435018 0.9504528040961903 0.3249878601250386 0.23491313213992226 0.40787137573243787 0.0984838499702429 1.944268726007613 1.4578828101113728e-05 4.836277384774882 6.175163054036155 PGPTPSGTNVGSSGRS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 2 PGPTPSGTNVGSSGRSPSK 19 1 P60468 P60468 SEC61B Protein transport protein Sec61 subunit beta 1 PGPTPSGTNVGS(0.002)S(0.019)GRS(0.855)PS(0.124)K;PGPTPSGTNVGS(0.029)S(0.255)GRS(0.645)PS(0.071)K 83.436 0.00072628 528470000.0 73227.0 48553.0 86927.0 73612.0 76029.0 34805.0 71913.0 61409.0 59242.0 63011.0 True False 96511.66278377983 64246.80774433594 85774.29118290717 56641.890694062844 65473.68570606818 32628.637847921964 78313.11768605963 51919.65008843609 62373.41117505996 60805.00406905572 1.5872322395402254 1.056603954361575 1.4106452667200555 0.9315333756040067 1.0767812075419037 0.5366110626498092 1.2879386965770137 0.8538713364688107 1.0257940465594413 1.0 15.891902437569257 -5.767773344824911 24.972112364233524 0.9538662669948951 1.3220048531297877 0.407101140186783 0.21616069253035863 144.16189481004062 568370.8265832196 0.05741258584329663 0.08755966074701901 1.7069730135499814e-06 5.767773344824911 0.3681385861348926 PGPTPSGTNVGSSGRS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 PGPTPSGTNVGSSGRSPSK 19 1 P60468 P60468 SEC61B Protein transport protein Sec61 subunit beta 1 PGPTPSGTNVGSSGRS(0.808)PS(0.192)K;PGPTPSGTNVGSS(0.005)GRS(0.978)PS(0.017)K;PGPTPSGTNVGSS(0.205)GRS(0.774)PS(0.021)K;PGPTPSGTNVGS(0.003)S(0.015)GRS(0.889)PS(0.093)K;PGPTPSGTNVGSS(0.001)GRS(0.987)PS(0.012)K;PGPTPSGTNVGSS(0.009)GRS(0.985)PS(0.006)K;PGPTPSGTNVGSSGRS(0.997)PS(0.002)K;PGPTPS(0.002)GT(0.002)NVGS(0.008)S(0.034)GRS(0.948)PS(0.006)K 193.59 5.4793e-15 1066344000.0 239840.0 158654.0 160857.0 209723.0 238760.0 179326.0 206539.0 208223.0 170320.3 161318.0 True False 280440.1749440739 174404.12061224174 164692.4409335697 197972.90024114013 191976.69195300067 169921.82887461898 186974.1307071322 202757.3668805051 172810.9121731494 190563.6764074148 1.4716349948271779 0.9152012802239141 0.8642383692339468 1.0388805672382433 1.0074149259304008 0.8916800519283398 0.9811635366825714 1.0639874854587759 0.9068407759078339 1.0 17.539913625893703 -4.758071096888479 24.99983929973422 0.9642370403049727 1.4716357002931881 0.8535238352457223 0.06317813311731771 34.62376025712427 256941.16715484747 0.016026776674004373 0.11302004181058586 1.745536373642167e-05 4.758071096888479 0.5073986599882154 PGPTPSGTNVGSSGRS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 3 PGPTPSGTNVGSSGRSPSK 19 1 P60468 P60468 SEC61B Protein transport protein Sec61 subunit beta 1 PGPTPSGTNVGS(0.001)S(0.234)GRS(0.761)PS(0.005)K;PGPTPSGTNVGS(0.003)S(0.04)GRS(0.947)PS(0.01)K;PGPTPS(0.001)GT(0.001)NVGS(0.023)S(0.074)GRS(0.851)PS(0.05)K 126.26 1.4388e-05 788410000.0 223307.0 180977.0 90745.0 59735.0 59908.0 55082.0 52229.0 49061.7 93677.0 28188.7 True False 220122.60123051115 180557.95887569367 83284.29638583002 64128.11117011846 56384.3292236597 52726.27126241342 54933.162061540286 51341.2856905415 83126.10979745806 33061.079235918274 6.6580585485353785 5.461344972656899 2.5191039830105773 1.9396859586013844 1.7054594262126368 1.5948139770685543 1.6615659056241487 1.5529222541157464 2.5143193059211466 1.0 15.012846199850992 -5.207109181082281 1.9568726902231734 1.709557846709173 6.81011438400663 0.960331136831227 0.35301963131333786 0.06559555648838337 0.43747855228692434 0.09546612729289203 0.4359303946006011 6.207129681600398e-06 5.207109181082281 5.100556537297456 PGS(ph)DTALTVDR ddPTM_PC-9_Lapatinib_30min_R1 2 PGSDTALTVDR 11 0 Q9ULS5 Q9ULS5 TMCC3 Transmembrane and coiled-coil domains protein 3 1 PGS(0.997)DT(0.003)ALTVDR;PGS(0.998)DT(0.002)ALTVDR 91.85799999999999 0.015887000000000002 2974500.0 20065.5 21693.0 15410.5 8917.400000000001 10942.8 12115.5 11405.8 10547.9 14630.7 4794.6 True False 19779.36229043795 21642.771191313946 14143.50817625027 9573.215343574353 10299.166018372554 11597.348307609915 11996.336514991992 11037.993941002102 12982.836497898856 5623.3402215970855 3.517368949947761 3.8487394214905213 2.515143601294209 1.7024072822069911 1.8315032725242946 2.062359354155554 2.13331152700288 1.962889227048617 2.308741066037011 1.0 12.457211619672124 -5.421398471530128 3.3371666852480986 1.920950414906323 3.6846320510151713 0.8102129573439163 0.3482459789508518 0.09474464032494062 1.9596697885919483 0.08985464782051661 0.20701159451015375 3.789671175461032e-06 5.421398471530128 1.7636816361088483 PGS(ph)LPLNAEACWPK ddPTM_PC-9_AZD4547_30min_R2 2 PGSLPLNAEACWPK 14 0 Q01581;D6RIW1 Q01581 HMGCS1 Hydroxymethylglutaryl-CoA synthase, cytoplasmic 1 PGS(1)LPLNAEACWPK;PGS(1)LPLNAEACWPK 69.26100000000001 0.030114 11757000.0 52603.0 54952.0 53312.0 78792.0 64665.0 48521.0 57367.0 66871.0 50899.0 57041.0 True False 69329.65978962928 72714.15935507078 52605.04804655803 60627.721724265015 55687.380949149614 45486.97419965584 62472.55186539528 56537.62349270965 53589.41722763204 55044.011951929184 1.259531370100275 1.3210185227518156 0.9556906588222324 1.1014408211598417 1.011688264979346 0.8263746152693292 1.1349563676418346 1.0271348596843715 0.9735739697613709 1.0 15.748298006061367 -5.258920937227187 24.997651857309137 1.0069347685133554 1.2902749719771278 0.6719915995880161 0.08001929331794708 121.85758932065266 1209521.2101093384 0.02065662128708928 0.049691133733803385 5.5090797939260325e-06 5.258920937227187 0.2833402034637724 PGS(ph)LPLNAEACWPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PGSLPLNAEACWPK 14 0 Q01581;D6RIW1 Q01581 HMGCS1 Hydroxymethylglutaryl-CoA synthase, cytoplasmic 1 PGS(1)LPLNAEACWPK 82.529 0.009135700000000002 3227900.0 16214.0 19169.0 10061.0 16504.0 16996.0 10838.0 16219.0 16457.0 11007.0 14600.0 True False 18958.70995890262 21071.97163649238 10300.892396554973 15579.334386689929 13665.755806806865 10269.63620079142 14682.618904608677 16025.02118763284 11167.956551801837 17246.86442646358 1.0992554640722045 1.221785660015948 0.5972617480977753 0.9033140170560514 0.7923617574124451 0.5954494652972221 0.8513210599649449 0.9291556303442645 0.647535475182708 1.0 14.074046475493539 -5.249049427303577 24.98218756125509 0.7864571197404241 1.160520610494412 0.5461074257205484 0.135257556162583 530.5702468275574 1069798.1772095677 0.0329322111405372 0.08577752244926079 5.635735115519346e-06 5.249049427303577 0.3740634907539878 PGS(ph)LPLNAEACWPK ddPTM_PC-9_Lapatinib_30min_R1 2 PGSLPLNAEACWPK 14 0 Q01581;D6RIW1 Q01581 HMGCS1 Hydroxymethylglutaryl-CoA synthase, cytoplasmic 1 PGS(1)LPLNAEACWPK;PGS(1)LPLNAEACWPK 113.69 0.00018536 9909900.0 52729.0 52134.0 37650.0 44740.0 41491.0 37074.0 43464.0 40103.0 32733.0 33013.4 True False 51977.07479068568 52013.28692610341 34554.56233320287 48030.328848264835 39050.58095444455 35488.43144371511 45714.35324901468 41966.33178319923 29046.264846229053 38719.7222024096 1.3423927609545465 1.3433279984345168 0.8924279506078812 1.2404616075803307 1.008544967092103 0.9165466440641613 1.1806477590422846 1.0838489895102499 0.7501671808074453 1.0 15.240780981473844 -1.5228787466094418 0.4620406562569494 0.98656428385792 10.948177799309933 0.41983834381831575 0.1437356891869978 91.14649975994948 1.0678560143453684 0.08590343593672782 863.0073244139985 0.029999999908188732 1.5228787466094418 9.961613515452013 PGSLT(ph)S(ph)KSY(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 PGSLTSKSYPR 11 1 J3QS10;Q14849-3 J3QS10 STARD3 3 PGS(0.001)LT(0.993)S(0.993)KS(0.424)Y(0.589)PR 76.165 0.034756 2517000.0 6033.1 8111.1 9055.1 10703.0 10330.0 10016.0 6114.8 9003.9 8306.4 10530.0 True False 7951.500303724351 10732.854453794482 8935.02345750276 8235.588709701606 8895.857808779327 9389.697936640896 6659.005354062775 7612.554144038647 8745.45934614831 10161.34790508255 0.7825241668723038 1.0562431828976226 0.8793147858891437 0.8104819150599392 0.8754604105553512 0.9240602747145694 0.6553269719986698 0.7491677497068046 0.8606593758859457 1.0 13.310804168174844 PGT(ph)GKLTSS(ph)S(ph)AWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PGTGKLTSSSAWK 13 1 P31629 P31629 HIVEP2 Transcription factor HIVEP2 3 PGT(0.995)GKLT(0.01)S(0.317)S(0.849)S(0.829)AWK 50.653 0.032415 11747000.0 8899.9 16328.0 31804.0 25622.0 55426.0 33030.0 30185.0 25997.0 25893.0 17525.0 True False 10406.477288962464 17948.93593200728 32562.32797734167 24186.482407644795 44565.67317887015 31297.848654008158 27325.65827952481 25314.606296098376 26271.636140256644 20702.143772176343 0.5026763123415633 0.8670085634382768 1.5728964273306516 1.1683081073058432 2.1527081286512155 1.511816795324957 1.319943411669784 1.2228012023624906 1.2690297405607671 1.0 14.337492550624146 -5.059234245703417 3.12965210192153 1.429520374065056 0.5283091840427473 0.49352881203537136 0.29917781789910447 0.20999143228649558 3.877197122347445 0.08003865753285576 0.329316064908701 8.725006402007053e-06 5.059234245703417 -0.9012111900223087 PGT(ph)S(ph)RATWRTDRDMGLMNAIGLQPR ddPTM_PC-9_Lapatinib_30min_R1 1 PGTSRATWRTDRDMGLMNAIGLQPR 25 3 A0A075B6T1;Q9C0C7-4;Q9C0C7-2;Q9C0C7-3;Q9C0C7;Q9C0C7-5 A0A075B6T1 AMBRA1 Activating molecule in BECN1-regulated autophagy protein 1 2 PGT(0.929)S(0.931)RAT(0.067)WRT(0.072)DRDMGLMNAIGLQPR 43.801 0.041129 0.0 14700.0 11795.0 12641.0 14294.0 14808.0 13085.0 10666.0 14479.0 13925.0 9454.7 True False 14490.375304350153 11767.689402182634 11601.705775671111 15345.22844338617 13937.022553648132 12525.385052624802 11218.233290861192 15151.74719818822 12356.619863249307 11088.932297404152 1.3067421565683341 1.0612103209375148 1.0462419162201033 1.3838328192316938 1.2568408012474475 1.129539320531059 1.0116603645859854 1.366384679049321 1.1143200744531476 1.0 13.436832841226227 -6.790985668991535 24.625129919728117 1.1402348633932116 1.2031049879676656 0.08749953675912192 0.13384984464757727 670.7471894123952 559023.8643137857 0.048753330743452436 0.04300403152195291 1.6181334325220747e-07 6.790985668991535 0.06287012457445407 PGVET(ph)S(ph)IS(ph)MRK ddPTM_PC-9_AZD4547_30min_R2 1 PGVETSISMRK 11 1 F5GXE6;J3KPV6;P37088-4;P37088;P37088-5;P37088-6;P37088-2 F5GXE6 SCNN1A Amiloride-sensitive sodium channel subunit alpha 3 PGVET(1)S(1)IS(1)MRK 67.385 0.014602 4053000.0 4316.3 3861.1 7474.5 10236.0 10353.0 7197.5 6320.3 10008.0 7192.8 8623.8 True False 5688.793615382711 5109.125067074242 7375.383246248461 7876.248344623534 8915.664655788227 6747.4391871977705 6882.794455956524 8461.493560961237 7572.996723607763 8321.883386880432 0.6835944882802822 0.6139385556794572 0.8862637101927981 0.9464502178726214 1.0713517891687714 0.8108067457223932 0.8270717259517656 1.0167762713787725 0.9100099546632316 1.0 13.022694356949104 -5.339957540657617 4.3251554274997766 0.9348339566182731 0.6480662370224677 0.68434498555904 0.07783304246493637 0.12109048372110069 4.183297559789543 0.021438012779179144 0.04844036574405326 4.5713287959710785e-06 5.339957540657617 -0.2867677195958054 PGVIPSESNGLSRGSPS(ph)KK ddPTM_PC-9_AZD4547_30min_R2 1 PGVIPSESNGLSRGSPSKK 19 2 O94782;C9JWX4;C9JC88 O94782 USP1 Ubiquitin carboxyl-terminal hydrolase 1 1 PGVIPS(0.001)ES(0.004)NGLS(0.015)RGS(0.44)PS(0.539)KK 40.961999999999996 0.04177 18290000.0 55665.0 24160.0 51129.0 95733.0 81793.0 47048.0 45170.0 46953.0 40428.0 69511.0 True False 73365.31209607258 31969.247525449664 50450.99605290485 73663.2359101059 70437.45379995025 44106.08112251207 49190.04249411523 39697.492722603165 42564.9415446022 67077.44104750191 1.0937404729574853 0.47660207405363236 0.7521306010641821 1.098181963410622 1.0500915464271945 0.6575397098299811 0.7333321266576128 0.5918158490048955 0.6345641825313401 1.0 16.03354003180148 -6.796539395416486 24.999852663213836 0.6985563832404909 0.8743977371436017 0.14144970056268513 0.20285418823797413 371.7460821805573 264772.1676939063 0.07410136998025262 0.06535378713177487 1.597572604599812e-07 6.796539395416486 0.17584135390311084 PGWLSS(ph)PTLGR ddPTM_PC-9_AZD4547_30min_R2 1 PGWLSSPTLGR 11 0 C9JS59;C9J266;Q5XPI4;Q5XPI4-2 C9JS59 RNF123 E3 ubiquitin-protein ligase RNF123 1 PGWLS(0.137)S(0.673)PT(0.19)LGR 68.132 0.037974 1700400.0 15108.0 17971.0 28903.0 24462.0 28171.0 26144.0 28607.0 33645.0 24878.0 26283.0 True False 19912.029734078256 23779.774307941036 28519.72733511527 18822.66383413254 24259.942916856013 24509.21154707863 31152.96758089779 28445.938335185918 26193.000290556378 25362.840169922583 0.7850867489868756 0.9375832575777976 1.1244689925908373 0.7421354906637806 0.9565152307203165 0.9663433346926084 1.2282917596051264 1.1215596575386513 1.032731354811685 1.0 14.630428689286703 -7.066055120663983 6.15847478201808 1.1060544155459284 0.9176299333903472 0.38129519871209105 0.11178006292346812 0.24651504743050964 17.908012273639784 0.04297987497814816 0.033478264586784975 8.589045024112491e-08 7.066055120663983 -0.18842448215558127 PGWLSS(ph)PTLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 PGWLSSPTLGR 11 0 C9JS59;C9J266;Q5XPI4;Q5XPI4-2 C9JS59 RNF123 E3 ubiquitin-protein ligase RNF123 1 PGWLS(0.045)S(0.953)PT(0.002)LGR;PGWLS(0.004)S(0.98)PT(0.015)LGR;PGWLS(0.138)S(0.852)PT(0.01)LGR;PGWLS(0.141)S(0.834)PT(0.024)LGR 150.09 0.00018391 41609500.0 200300.0 242197.0 214981.0 268205.0 258546.0 191642.0 266211.0 191322.0 211814.0 204815.0 True False 234206.83389467103 266240.71753578953 220106.9623599828 253178.34338234257 207885.76728799008 181591.95615354012 240993.5668792632 186300.0002224155 214911.37903728156 241946.33818535233 0.9680114840806057 1.1004122630358868 0.9097346296324658 1.0464235387120657 0.8592226228641293 0.7505464125455149 0.9960620552754172 0.7700054550099997 0.8882605153240236 1.0 17.884327578884793 -6.270406762108163 24.057051410118863 0.8654452441540793 1.0059923315640245 0.3294722029904775 0.08904683435922511 407.3285045065381 1092749.4778527243 0.02600859929777784 0.029946356211062095 5.36529045520815e-07 6.270406762108163 0.14054708740994515 PGWLSS(ph)PTLGR ddPTM_PC-9_Lapatinib_30min_R1 4 PGWLSSPTLGR 11 0 C9JS59;C9J266;Q5XPI4;Q5XPI4-2 C9JS59 RNF123 E3 ubiquitin-protein ligase RNF123 1 PGWLS(0.045)S(0.955)PT(0.001)LGR;PGWLS(0.005)S(0.985)PT(0.01)LGR;PGWLS(0.221)S(0.557)PT(0.221)LGR;PGWLS(0.129)S(0.867)PT(0.004)LGR 155.47 0.00013857 37334600.0 178358.0 275304.0 228543.0 222940.0 226613.0 216888.0 223676.0 237263.0 222884.0 204782.0 True False 175814.58221314827 274666.5505026272 209753.0767414919 239335.75130603806 213284.06887829967 207612.2058306219 235256.84882492648 248287.10515116624 197780.4568474298 240178.2958451372 0.7320169443058687 1.143594384896991 0.8733223624699921 0.9964920038418359 0.8880239079380492 0.864408688970325 0.9795091933561557 1.033761623953138 0.823473478948136 1.0 17.873746259571327 -10.969810798600095 3.4323458675011023 1.0008221310402523 0.9347917627222139 0.033116473735742114 0.11118858783298408 150926929.26088053 146507214.0228828 1129638.3014172327 0.025626953689008723 1.0719862168102373e-11 10.969810798600095 -0.06603036831803843 PHS(ph)IDGR ddPTM_PC-9_AZD4547_30min_R2 2 PHSIDGR 7 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 PHS(1)IDGR;PHS(1)IDGR 82.645 0.013071000000000001 6620300.0 15829.6 13812.0 14786.3 9114.3 12404.9 17152.1 11844.3 13354.4 14932.5 15534.0 True False 20863.083523865844 18276.458891618808 14590.224000803206 7013.13894953129 10682.693759160382 16079.576475544956 12898.419754550561 11290.7843335832 15721.801464697057 14990.159388181617 1.3917853028510487 1.2192304576846689 0.9733201377635968 0.4678495250064195 0.7126471095152409 1.0726754839059447 0.8604591465998551 0.7532130940839069 1.0488081585771711 1.0 13.871728102883033 -5.245569706723567 2.9183541292016937 0.8341365909210315 1.3473578705731835 0.5271689708557845 0.1727386578940245 0.20741931376877049 3.5032263829389567 0.04841771688051063 0.14981203179649694 5.681071998191893e-06 5.245569706723567 0.5132212796521519 PHS(ph)IDGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PHSIDGR 7 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 PHS(1)IDGR 76.679 0.017514 7317000.0 5143.8 7421.3 5818.0 4864.4 7127.3 4272.7 5983.2 4196.1 4162.8 5847.5 True False 6014.543745319065 8158.037618336944 5956.723184887873 4591.863438597583 5730.7567287511465 4048.6320903415303 5416.427981383232 4085.9568211354544 4223.673074756126 6907.605461215469 0.8707132709141063 1.1810225213559675 0.8623427059251473 0.664754735107525 0.829630001442317 0.5861122371672236 0.7841252676915557 0.5915156625660095 0.6114525646363311 1.0 12.753969968078588 -5.527975779475113 4.749435163445511 0.7099530859289106 1.027996852918656 0.4269814886654669 0.13921363767595807 0.14553193525321007 8.875903323024959 0.03540102956993908 0.06820781121860722 2.9649967422467303e-06 5.527975779475113 0.31804376698974546 PHS(ph)IDGR ddPTM_PC-9_Lapatinib_30min_R1 3 PHSIDGR 7 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 PHS(1)IDGR;PHS(1)IDGR;PHS(1)IDGR 76.17 0.017936 10563000.0 11056.2 20638.8 14411.7 15013.3 17265.2 14037.800000000001 19896.3 24835.1 13711.300000000001 21117.4 True False 10898.536560541243 20591.01212664409 13226.825656770767 16117.428164900639 16249.694880689214 13437.436017710092 20926.433060656418 25989.02941099 12166.98900761006 24767.514452833228 0.4400335197662326 0.8313717618236264 0.5340392828662592 0.650748713424367 0.6560890440433503 0.5425427748634237 0.8449145391843138 1.0493192387343915 0.4912478816063936 1.0 14.596161473547676 -7.27555474005955 23.144516464168586 0.8504804311799139 0.619851101673936 0.3213495236541395 0.16842073379896588 367.2259805926787 602124.2555891799 0.06582887889588497 0.044683844279356795 5.302067592247454e-08 7.27555474005955 -0.23062932950597792 PHT(ph)VLLNATVQVTTSNQT(ph)ILS(ph)S(ph)PAFK ddPTM_PC-9_Lapatinib_30min_R1 1 PHTVLLNATVQVTTSNQTILSSPAFK 26 0 Q99935 Q99935 PROL1 Proline-rich protein 1;Opiorphin 4 PHT(0.991)VLLNAT(0.055)VQVT(0.38)T(0.38)S(0.38)NQT(0.601)ILS(0.607)S(0.605)PAFK 41.76 0.040527999999999995 0.0 1331.6 1335.2 917.25 2201.0 2386.0 2520.3 2714.1 584.94 1190.1 913.21 True False 1312.6111398144676 1332.108426434444 841.8372456873925 2362.8688823207626 2245.660171056486 2412.51264410625 2854.6228178067076 612.1184478284556 1056.0584056914172 1071.057131724163 1.2255285931399913 1.24373237148428 0.7859872463873355 2.206109097576402 2.0966763625778526 2.252459343809833 2.6652386070306093 0.571508680254135 0.9859963342864809 1.0 10.06481972222625 -5.753531224152037 24.999868615268493 1.7466603582501965 1.1009477230821154 0.1498609458774658 0.6391732887874495 347.297878672397 1097892.7551679139 0.18902476141903782 0.3199358759237607 1.763878943605971e-06 5.753531224152037 -0.6457126351680811 PIPEAEEAQRPEPVGT(ph)SSNADSASPDLGPR ddPTM_PC-9_AZD4547_30min_R2 1 PIPEAEEAQRPEPVGTSSNADSASPDLGPR 30 1 B4DKV7;Q8TE68-2;Q8TE68;K7EKX9;K7EN83;Q8TE68-3 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 PIPEAEEAQRPEPVGT(0.254)S(0.254)S(0.254)NADS(0.058)AS(0.18)PDLGPR 73.839 4.283500000000001e-06 8068100.0 4336.3 6543.4 5409.8 4895.2 4994.8 4129.1 4077.1 6823.0 5036.5 4453.2 True False 5715.153199356866 8658.426086838876 5338.062517299477 3766.687270086079 4301.358236523814 3870.906724259576 4439.954001610738 5768.662126942295 5302.719107781463 4297.294823448586 1.3299420761572154 2.014855029167041 1.24219136377887 0.8765252152430414 1.0009455746561897 0.9007775550184773 1.033197437928559 1.3423938463484184 1.2339667920494277 1.0 12.069213043793084 -5.467924845622756 6.820096723968466 1.059605497168292 1.6674766754527612 0.5905701562283084 0.20291310757346895 0.15836092929416454 16.16243278200235 0.05365727083578924 0.11127116997779393 3.404671022137651e-06 5.467924845622756 0.6078711782844692 PIPEAEEAQRPEPVGT(ph)SSNADSASPDLGPR ddPTM_PC-9_Lapatinib_30min_R1 1 PIPEAEEAQRPEPVGTSSNADSASPDLGPR 30 1 B4DKV7;Q8TE68-2;Q8TE68;K7EKX9;K7EN83;Q8TE68-3 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 PIPEAEEAQRPEPVGT(0.252)S(0.252)S(0.18)NADS(0.104)AS(0.211)PDLGPR 74.665 1.8589e-06 9010200.0 3331.4 8690.8 6744.8 10050.0 14131.0 11919.0 10508.0 11668.0 8973.5 12929.0 True False 3283.8936250960614 8670.676986561157 6190.268579680918 10789.1105258172 13299.842362614925 11409.252154546042 11052.052823961127 12210.137876128185 7962.809934855845 15163.7604231904 0.21656195649687943 0.5718025571876503 0.4082278014768653 0.7115062639289054 0.8770807498564189 0.7524025595324974 0.7288464414841905 0.8052183320869967 0.5251210591983554 1.0 13.888339947778036 -5.806630883367856 4.308987916062969 0.7696033349797742 0.41272673953646155 0.6043061776935141 0.138637769885366 0.1420999590055804 5.595880781896875 0.03767648851287353 0.059960587915707034 1.5608785649636356e-06 5.806630883367856 -0.3568765954433126 PIPEAEEAQRPEPVGTSSNADS(ph)ASPDLGPR ddPTM_PC-9_AZD4547_30min_R2 1 PIPEAEEAQRPEPVGTSSNADSASPDLGPR 30 1 B4DKV7;Q8TE68-2;Q8TE68;K7EKX9;K7EN83;Q8TE68-3 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 PIPEAEEAQRPEPVGT(0.02)S(0.02)S(0.02)NADS(0.47)AS(0.47)PDLGPR 76.79899999999999 6.3432e-05 0.0 2933.3 3173.3 2908.4 2854.3 2648.1 3511.6 2529.6 4416.6 3142.1 2706.6 True False 3866.028383569749 4199.007167736316 2869.8327156852 2196.2852334954027 2280.4570245332566 3292.019096875815 2754.7294995154703 3734.1159533714394 3308.184991275715 2611.8427578249243 1.4801918576404953 1.607679924511666 1.0987769868945416 0.8408948918978617 0.8731218668126725 1.2604200949743714 1.0547072526714962 1.4296863554225276 1.2666095542561249 1.0 11.350852328814913 -5.266134778923081 24.494555707172584 1.1046957502073504 1.5439359132038835 0.5082478828617494 0.1734716421411855 238.44814799501555 1243924.8700745788 0.05006884539507328 0.11010564166939298 5.418327119758761e-06 5.266134778923081 0.439240162996533 PIPEAEEAQRPEPVGTSSNADSAS(ph)PDLGPR ddPTM_PC-9_AZD4547_30min_R2 1 PIPEAEEAQRPEPVGTSSNADSASPDLGPR 30 1 B4DKV7;Q8TE68-2;Q8TE68;K7EKX9;K7EN83;Q8TE68-3 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 PIPEAEEAQRPEPVGT(0.001)S(0.002)S(0.002)NADS(0.025)AS(0.97)PDLGPR 138.02 6.206e-15 7960800.0 9661.6 12537.0 13977.0 14492.0 14894.0 14790.0 15636.0 14266.0 13295.0 13507.0 True False 12733.787826235797 16589.340075602744 13791.655847590437 11151.093299168058 12826.225189153862 13865.178961952759 17027.573709054355 12061.517500067235 13997.746557719554 13034.124041210836 0.9769576985744921 1.2727621758969878 1.0581191190128667 0.8555307026318703 0.984049649105713 1.0637599364647998 1.3063842000595645 0.9253799842575958 1.0739307462060335 1.0 13.67000600930707 -7.856800637996693 0.005665567986222263 3.258810610865502e-08 2.097446490452833 0.0072896945773330835 0.13429964160606353 26770.657497426175 153.244373622855 28327.10675952174 28390.687065707734 1.3905908326280605e-08 7.856800637996693 2.097446457864727 PIPEAEEAQRPEPVGTSSNADSAS(ph)PDLGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 PIPEAEEAQRPEPVGTSSNADSASPDLGPR 30 1 B4DKV7;Q8TE68-2;Q8TE68;K7EKX9;K7EN83;Q8TE68-3 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 PIPEAEEAQRPEPVGT(0.005)S(0.024)S(0.024)NADS(0.049)AS(0.896)PDLGPR;PIPEAEEAQRPEPVGT(0.003)S(0.004)S(0.005)NADS(0.032)AS(0.956)PDLGPR;PIPEAEEAQRPEPVGT(0.004)S(0.015)S(0.015)NADS(0.021)AS(0.944)PDLGPR;PIPEAEEAQRPEPVGTSSNADS(0.043)AS(0.956)PDLGPR 119.35 1.9985999999999998e-17 19647400.0 55998.2 74096.0 59707.0 63081.0 59681.1 45606.4 57015.0 36329.7 32141.1 48373.799999999996 True False 65477.58924513513 81451.76119659565 61130.64132005842 59546.77608136132 47987.01687936104 43214.72009852129 51614.1264471461 35376.08386949895 32611.102782512746 57143.587013209915 1.1458431762430077 1.4253876148476012 1.069772559183707 1.042055271531972 0.8397620693336569 0.7562479423724542 0.9032356760385805 0.6190735604560673 0.570687009462217 1.0 15.802303979417449 -5.974598590704423 1.08737815079706 0.7420076520383181 1.2952609997841065 0.6738829508983025 0.1390990499930129 0.2944663014444498 0.705511001075253 0.05442253926671552 0.1149503455359028 1.0602332238102005e-06 5.974598590704423 0.5532533477457884 PIPEAEEAQRPEPVGTSSNADSAS(ph)PDLGPR ddPTM_PC-9_Lapatinib_30min_R1 2 PIPEAEEAQRPEPVGTSSNADSASPDLGPR 30 1 B4DKV7;Q8TE68-2;Q8TE68;K7EKX9;K7EN83;Q8TE68-3 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 PIPEAEEAQRPEPVGT(0.045)S(0.016)S(0.016)NADS(0.178)AS(0.744)PDLGPR;PIPEAEEAQRPEPVGT(0.004)S(0.004)S(0.004)NADS(0.086)AS(0.902)PDLGPR 100.92 5.8485e-13 10669500.0 6414.879999999999 15463.5 13846.3 13695.9 15783.1 16894.7 13640.4 16827.5 18144.4 13193.8 True False 6323.4026348550815 15427.695215824602 12707.910662263661 14703.142174183058 14854.769088768506 16172.153064469263 14346.633169010205 17609.36708180898 16100.78660299754 15474.33075036658 0.4086381981143374 0.9969862648476172 0.8212252191884044 0.9501633648249859 0.9599619736974152 1.0450954762024944 0.9271246298435453 1.1379727734843603 1.0404835506450654 1.0 13.917589395192161 -4.760636662235029 24.994709090906586 0.9837057594295598 0.40863752881311743 0.8277801655458258 0.07907137680365715 8.205775214324447 255351.1300708546 0.020975650093673456 0.12278585021479606 1.7352551330668662e-05 4.760636662235029 -0.5750682306164424 PIPQT(ph)PESAGNK ddPTM_PC-9_AZD4547_30min_R2 3 PIPQTPESAGNK 12 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;P52948-4;P52948-3 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 PIPQT(0.845)PES(0.155)AGNK;PIPQT(0.762)PES(0.238)AGNK;PIPQT(0.999)PES(0.001)AGNK 115.14 0.0011213 22671000.0 122450.0 144208.0 114790.0 69853.0 88136.0 131808.0 140864.0 135612.0 134358.0 112925.0 True False 161386.55288177665 190820.4158588592 113267.8095975465 53749.47006809175 75899.83773810003 123566.02492339915 153400.62311027353 114656.28145374438 141459.88958270676 108971.5301216948 1.4809974008949582 1.7511033904521578 1.0394257056962841 0.4932432352566456 0.6965107092957059 1.1339294289564057 1.407712848841915 1.052167307605033 1.298136214337179 1.0 16.733591740474004 -7.0031963301728375 24.928213882716843 1.204847066803373 1.0749027389758408 0.01499301467116787 0.3492932782060745 697.3538986971462 5438718.89638732 0.14358374503421562 0.12420586263249994 9.926671949620515e-08 7.0031963301728375 -0.1299443278275323 PIPQT(ph)PESAGNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PIPQTPESAGNK 12 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;P52948-4;P52948-3 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 PIPQT(0.5)PES(0.5)AGNK 98.40700000000001 0.0089685 7657700.0 30457.0 51393.0 29993.0 33175.0 35442.0 16291.0 33610.0 25213.0 19690.0 25639.0 True False 35612.76854682975 56494.95739549551 30708.146869085904 31316.31230480117 28497.39452252582 15436.67128133355 30426.21748467213 24551.185465381688 19977.92900017972 30287.14774178767 1.1758376473891015 1.865311249416481 1.0139002566662088 1.0339802404566985 0.9409071717640649 0.5096772866477395 1.0045917081420177 0.8106139830231692 0.6596173786485627 1.0 14.886418099890326 -5.444446219441973 4.833828091411087 0.8499493836665034 1.5191105468743011 0.588930094223778 0.2199300099039928 0.13745486256394204 5.724721050755935 0.05688647718931096 0.12093286685112255 3.593798975620453e-06 5.444446219441973 0.6691611632077977 PIPQT(ph)PESAGNK ddPTM_PC-9_Lapatinib_30min_R1 3 PIPQTPESAGNK 12 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;P52948-4;P52948-3 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 PIPQT(0.831)PES(0.169)AGNK;PIPQT(0.71)PES(0.29)AGNK;PIPQT(0.948)PES(0.052)AGNK 130.19 0.000375 25877000.0 39436.3 132201.0 107850.0 116882.0 153387.0 148540.0 188762.0 189836.0 129302.0 152380.0 True False 38873.93113026831 131894.89670690527 98982.98931303924 125477.8921869218 144365.07823044472 142187.2904636523 198535.17274044082 198656.47359038988 114738.64714957714 178718.67996641318 0.21751465004986573 0.7380028586362234 0.5538480327386104 0.7020972413767996 0.8077783377628764 0.7955927745794324 1.1108809262565713 1.111559651334285 0.6420070200336088 1.0 17.447330909523863 -4.930262825942856 0.4680056635732037 0.9776842475621158 1.118030331960962e-13 0.6035623262314375 0.16197369068234543 3.06914007540814 0.577495359779958 0.11497101847217327 1.6420665503681575 1.1741867466017715e-05 4.930262825942856 -0.977684247562004 PIPQTPES(ph)AGNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PIPQTPESAGNK 12 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;P52948-4;P52948-3 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 PIPQT(0.273)PES(0.727)AGNK 117.31 0.00063658 7424400.0 36549.0 57822.0 43645.0 40241.0 40069.0 24936.0 45951.0 22060.0 21421.0 35919.0 True False 42736.02382434511 63562.186027714655 44685.66232458422 37986.42723308228 32217.767087723223 23628.31226268082 41598.18862356947 21480.948374502044 21734.241600449448 42430.830365352434 1.007192728880505 1.4980189046598853 1.0531413582957596 0.8952553345291281 0.7593008859433293 0.5568666005173185 0.9803764919372666 0.5062580248734103 0.5122275810608903 1.0 15.372825291792381 -5.816131433321054 1.851818069818575 0.6994607486026159 1.256466337286766 0.529476159878049 0.19959020682817377 0.24491641085280313 1.7149514467694342 0.06094916876681384 0.11757605887074872 1.5271038310835234e-06 5.816131433321054 0.5570055886841501 PIS(ph)PGLSYASHTVGFTPPTSLTR ddPTM_PC-9_AZD4547_30min_R2 2 PISPGLSYASHTVGFTPPTSLTR 23 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 PIS(0.372)PGLS(0.324)Y(0.272)AS(0.033)HTVGFTPPTSLTR;PIS(0.874)PGLS(0.058)Y(0.054)AS(0.013)HT(0.001)VGFTPPTSLTR 74.277 0.00024721 25697000.0 17554.5 23993.0 33877.0 36990.0 31355.0 29786.0 26798.0 41272.0 30987.0 42042.0 True False 23136.465843717033 31748.26804131264 33427.76884516144 28462.52698980308 27001.899476696584 27923.476711340434 29182.97008539515 34894.36073621023 32624.90955878572 40570.12237658888 0.5702833634307203 0.7825529276597174 0.8239504070229534 0.7015637450043156 0.665561203539236 0.6882768667085354 0.7193217169646814 0.860099962536621 0.8041609846760539 1.0 15.30813003387652 -8.503372373500067 0.8540360837353916 0.9949072883467267 0.7099013930455755 0.6120826953342546 0.07081345872600896 0.4565143394552811 0.7431794369727068 0.0701996612213013 0.02511983486923962 3.137817107743421e-09 8.503372373500067 -0.28500589530115117 PIS(ph)PGLSYASHTVGFTPPTSLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PISPGLSYASHTVGFTPPTSLTR 23 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 PIS(0.373)PGLS(0.242)Y(0.242)AS(0.134)HT(0.004)VGFT(0.003)PPTSLTR 56.332 0.0049137 11234000.0 9501.7 17458.0 14839.0 10948.0 13762.0 13080.0 14832.0 9638.9 9460.7 7254.8 True False 11110.150142870669 19191.114864097457 15192.818037220883 10334.6190538949 11065.434891343606 12394.061773975984 13427.005585619074 9385.88908825874 9599.044839614033 8570.037811034797 1.2963945303211168 2.239326743621474 1.7727830812669905 1.205901220247596 1.2911769043884183 1.4462085287438715 1.5667381966892182 1.0951980954125373 1.12007030205331 1.0 13.065085854189133 -6.38612599581906 0.31875069277142776 0.9857385106182375 1.9761939395380774 0.3890204923616931 0.27798409789629147 2.822525027465585 0.5005938041372694 0.35937249859603576 1.0162935066180327 4.1103045725409687e-07 6.38612599581906 0.99045542891984 PIS(ph)PSPSAILER ddPTM_PC-9_AZD4547_30min_R2 1 PISPSPSAILER 12 0 Q5T5P2;Q5T5P2-2;Q5T5P2-7;Q5T5P2-10;Q5T5P2-3;Q5T5P1;Q5T5P2-4;Q5T5P2-8;Q5T5P2-6;Q5T5P0;Q5T5P2-9 Q5T5P2;Q5T5P2-9 KIAA1217 Sickle tail protein homolog 1 PIS(0.73)PS(0.181)PS(0.089)AILER 93.766 0.0051393 3183600.0 7798.2 8636.7 12785.0 9895.3 9866.3 9321.5 10545.0 12841.0 11477.0 10958.0 True False 10277.86538736358 11428.344375126278 12615.462546429399 7614.0914658610045 8496.534549734703 8738.625131429528 11483.48457162818 10856.718506824851 12083.650789240124 10574.363755355618 0.9719606422805466 1.0807595274314394 1.1930233192554986 0.7200519711651381 0.8035031465067055 0.8263972503313648 1.0859740441416268 1.026701819419275 1.1427307655385028 1.0 13.368283240567745 -9.452159133459462 10.657726798332957 0.9999999997450044 0.9791093687192967 0.00035014633294305764 0.14760398728107274 0.0 0.0 0.155225775505428 0.03764778048395849 3.530537807108621e-10 9.452159133459462 -0.020890631025707762 PIS(ph)PSPSAILER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PISPSPSAILER 12 0 Q5T5P2;Q5T5P2-2;Q5T5P2-7;Q5T5P2-10;Q5T5P2-3;Q5T5P1;Q5T5P2-4;Q5T5P2-8;Q5T5P2-6;Q5T5P0;Q5T5P2-9 Q5T5P2;Q5T5P2-9 KIAA1217 Sickle tail protein homolog 1 PIS(0.826)PS(0.135)PS(0.039)AILER 64.827 0.043078 2159100.0 6673.2 12114.0 7466.9 8692.3 10141.0 6476.6 12951.0 8093.5 5074.4 8591.1 True False 7802.840958292158 13316.597861363069 7644.939214375945 8205.298611816828 8153.943847777619 6136.955694597318 11724.187522879763 7881.054200772096 5148.603500178362 10148.598422889825 0.768858972751657 1.3121612765096633 0.7533000022084863 0.8085154491195603 0.8034551676994797 0.6047096789991827 1.1552518913780498 0.7765657751317306 0.5073216305973699 1.0 13.308992876618243 -5.320501542018813 24.99991737581284 0.7991376491799075 1.0405141145875436 0.17224090318118823 0.20986374536155242 368.9026714463271 156148.79979477174 0.05287871125581428 0.11007586837337738 4.78077668669416e-06 5.320501542018813 0.24137646540763613 PISPGLS(ph)YASHTVGFTPPTSLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PISPGLSYASHTVGFTPPTSLTR 23 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 PIS(0.081)PGLS(0.5)Y(0.404)AS(0.014)HTVGFTPPTSLTR 73.796 0.00027227 11164000.0 3745.4 8704.3 9160.1 8506.2 13773.0 8403.7 10169.0 5024.7 6041.3 5707.3 True False 4379.422244978037 9568.405379285334 9378.511523872698 8029.625191472488 11074.279520307773 7962.995178131647 9205.718702815564 4892.806949109722 6129.642583483278 6741.98831103806 0.6495742862395649 1.419226041021138 1.3910601874699327 1.190987705856193 1.6425836132312537 1.1811048626552112 1.365430831101243 0.7257216600478472 0.9091743118936824 1.0 12.718958410705355 -7.75690499445853 24.999976516005272 0.8630859582778189 1.2824948347062686 0.3291567513897139 0.25020088017087017 117.72390569726753 649072.5153851294 0.11910219329676477 0.06578122711268652 1.7502295240604058e-08 7.75690499445853 0.4194088764284497 PISPGLSY(ph)ASHTVGFTPPTSLTR ddPTM_PC-9_Lapatinib_30min_R1 2 PISPGLSYASHTVGFTPPTSLTR 23 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 PIS(0.239)PGLS(0.282)Y(0.303)AS(0.172)HT(0.003)VGFTPPTSLTR;PIS(0.045)PGLS(0.079)Y(0.516)AS(0.356)HT(0.003)VGFTPPTSLTR 60.93899999999999 0.0081775 21556500.0 11242.0 18145.4 19584.7 13995.8 24365.0 21078.0 18572.199999999997 23762.0 17579.4 17854.4 True False 11081.687018469684 18103.38544115006 17974.521565128238 15025.097820620125 22931.898603433066 20176.543075217858 19533.77764152748 24866.069267445826 15599.422852711294 20940.509250507435 0.529198544596099 0.864515051882579 0.8583612437549806 0.717513487417028 1.0950974653530632 0.9635173067593347 0.9328224737922327 1.1874624905238762 0.7449399948252589 1.0 14.354008907025817 -4.191973942618702 0.6117585538665675 0.9845933310339794 8.640474237585385e-12 0.4557183180969765 0.1345275286564961 6.274764608880707 1.0525954877073191 0.06146531164344725 5.100559631458186 6.42726279311267e-05 4.191973942618702 -0.984593331025339 PISPS(ph)SPSYRPPNTR ddPTM_PC-9_Lapatinib_30min_R1 1 PISPSSPSYRPPNTR 15 1 Q9C0D6 Q9C0D6 FHDC1 FH2 domain-containing protein 1 1 PIS(0.096)PS(0.3)S(0.3)PS(0.3)Y(0.005)RPPNTR 86.738 0.025979000000000002 2432900.0 16367.0 20863.0 19170.0 19614.0 22268.0 15301.0 17846.0 18208.0 19438.0 15654.0 True False 16133.603578659802 20814.693005318888 17593.916598339943 21056.47899038593 20958.240020572444 14646.6118983731 18769.97855885137 19054.010151571994 17248.68774878563 18359.773042356126 0.8787474410189856 1.1337118905173416 0.9582861704091142 1.1468812246103743 1.1415304520497958 0.7977556075765895 1.022342624581954 1.0378129461412327 0.9394826237226781 1.0 14.1642606042766 -6.707665327148831 24.99999877345687 0.9657654445888982 1.0564637123708998 0.17213100707498685 0.10054011592416354 176.03513914622084 81839.3236491783 0.03262256832891964 0.032622542306501065 1.9603547658977086e-07 6.707665327148831 0.09069826778200152 PIT(ph)PVYTVAPNVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PITPVYTVAPNVQR 14 0 B7Z8Z7;A0AV96-2;A0AV96 B7Z8Z7 RBM47 RNA-binding protein 47 1 PIT(0.999)PVYT(0.001)VAPNVQR;PIT(0.919)PVYT(0.081)VAPNVQR 119.96 0.00028972 4671600.0 25043.0 42837.0 23293.0 27286.0 25145.0 18070.6 24432.0 10908.5 18550.800000000003 23537.0 True False 29282.28527820391 47089.57426012961 23848.393459194416 25757.253882405577 20218.01775489281 17122.945924526797 22117.624087637894 10622.163433511141 18822.070355334392 27804.071781210525 1.0531653604056777 1.6936215181242578 0.8577302506933793 0.9263842391534843 0.7271603207612121 0.615843105976232 0.7954814770182177 0.3820362541535877 0.6769537391301801 1.0 14.763008554167433 -5.430592144406053 4.860374643671701 0.7151223807584342 1.3705949073807913 0.5778075048631867 0.21530404160703573 0.14037612509013717 5.436189077726384 0.056132566807906854 0.11993105502319047 3.710289997936972e-06 5.430592144406053 0.6554725266223571 PIT(ph)PVYTVAPNVQR ddPTM_PC-9_Lapatinib_30min_R1 1 PITPVYTVAPNVQR 14 0 B7Z8Z7;A0AV96-2;A0AV96 B7Z8Z7 RBM47 RNA-binding protein 47 1 PIT(0.993)PVYT(0.007)VAPNVQR 92.45700000000001 0.01012 2757200.0 15317.0 19138.0 14961.0 13852.0 13394.0 13147.0 14622.0 16912.0 12419.0 10579.0 True False 15098.57677120622 19093.687136835222 13730.964331130084 14870.722288917394 12606.191253617173 12584.733457153863 15379.05561400453 17697.793260291382 11020.241442132354 12407.566054368564 1.2168846577198098 1.5388745103728503 1.1066605868518078 1.198520501422725 1.0160083934575286 1.0142789812287898 1.2394901261548987 1.426371069292852 0.8881872072123486 1.0 13.598932514704837 -5.283826467826399 24.564120733572118 1.1272578255245964 1.377879593955459 0.30228243707434466 0.16059145752005943 699.1156219457432 767100.1888277138 0.04157654102341699 0.08666191808138027 5.202038142001635e-06 5.283826467826399 0.2506217684308625 PKGS(ph)LSMGPAPR ddPTM_PC-9_AZD4547_30min_R2 2 PKGSLSMGPAPR 12 1 V9GYD1;M0QX12;Q86YV0-2;Q86YV0 V9GYD1 RASAL3 RAS protein activator like-3 1 PKGS(0.969)LS(0.031)MGPAPR;PKGS(0.898)LS(0.102)MGPAPR 103.97 0.0042672 218080000.0 494640.0 540980.0 689450.0 982300.0 949820.0 852740.0 703380.0 959480.0 767060.0 835310.0 True False 651925.2308488531 715841.2055595093 680307.4425213733 755845.9113837136 817953.888086619 799418.0329963214 765979.457372386 811214.4126569843 807605.2256159729 806066.0511485782 0.8087739583126135 0.8880676770092155 0.8439847349382732 0.9376972399553299 1.0147479687565326 0.991752514396576 0.9502688474237663 1.0063870218837154 1.0019094892598461 1.0 19.62053853621756 -5.920879036560821 3.138682555705353 0.9918612417818995 0.8501626335115096 0.8768967190032659 0.024600950617449907 0.08158048360758008 1.6196239686584475 0.007245939682507147 0.011284346095509913 1.1998334445570113e-06 5.920879036560821 -0.14169860827038994 PKGS(ph)LSMGPAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PKGSLSMGPAPR 12 1 V9GYD1;M0QX12;Q86YV0-2;Q86YV0 V9GYD1 RASAL3 RAS protein activator like-3 1 PKGS(0.861)LS(0.139)MGPAPR 103.97 0.0042672 80235000.0 290380.0 316420.0 318560.0 378200.0 434590.0 330240.0 321830.0 319070.0 315290.0 261070.0 True False 339535.59873357246 347832.0864530704 326155.6785455282 357010.68014094373 349435.2092304179 312921.63304570544 291343.93255257414 310694.7505826091 319900.51977992145 308399.92437101714 1.1009587613422949 1.1278604790921247 1.0575737954888413 1.1576224633292904 1.1330586735489394 1.0146618345770038 0.9446952140042552 1.0074410725497818 1.0372911745434432 1.0 18.234442885897373 -6.824727364170286 5.547610141535279 0.9960843451701763 1.1151861789213986 0.7593436709235525 0.03229917927410347 0.09966520931512361 5.912825360083655 0.011768805461095362 0.010472995387870951 1.497175238647479e-07 6.824727364170286 0.1191018337512223 PKGS(ph)LSMGPAPR ddPTM_PC-9_Lapatinib_30min_R1 1 PKGSLSMGPAPR 12 1 V9GYD1;M0QX12;Q86YV0-2;Q86YV0 V9GYD1 RASAL3 RAS protein activator like-3 1 PKGS(0.989)LS(0.011)MGPAPR 76.868 0.039476 129130000.0 172250.0 167960.0 175780.0 165900.0 130220.0 143400.0 117230.0 143600.0 140470.0 82150.0 True False 169793.68341321868 167571.09893943157 161328.04693042248 178100.83942617656 122560.71562237028 137267.1162817269 123299.5957892047 150272.18023757322 124648.78938532363 96349.51804200588 1.7622681136733145 1.7392001781096087 1.6744042960348557 1.848487081674132 1.2720428509973138 1.4246788055741184 1.2797115989251684 1.5596567921809268 1.2937147161543663 1.0 16.555989829462796 -1.5228787511648827 0.07985047221256318 0.5604890390192021 3.9597205756465828 0.7153634884698898 0.13891973672034558 109.38900006731973 0.6393880491072237 4.120106548491812 41.04784087039766 0.029999999593510025 1.5228787511648827 3.3992315366273806 PKPS(ph)SSPVIFAGGQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PKPSSSPVIFAGGQDR 16 1 Q15366-2;Q15366;Q15366-6;Q15366-3;H3BSS4 Q15366-2 PCBP2 Poly(rC)-binding protein 2 1 PKPS(0.477)S(0.477)S(0.047)PVIFAGGQDR;PKPS(0.385)S(0.231)S(0.385)PVIFAGGQDR 108.96 0.0035527 4884300.0 27802.0 43832.0 30670.0 32437.0 31139.0 17212.800000000003 27366.0 25445.0 21774.0 26154.0 True False 32508.32948547002 48183.351284403696 31401.289116622702 30619.660052172898 25037.536483181862 16310.1304665974 24773.694367317406 24777.09571120603 22092.40355763907 30895.513165049917 1.0522022829594744 1.5595582124497736 1.0163705308557534 0.9910714183187909 0.8103939348547606 0.5279125929860906 0.8018541150286597 0.8019642068685477 0.7150683479383269 1.0 14.915109715913951 -5.781912118616664 1.6948553161372095 0.7581563269383464 1.2991684675105228 0.5834096048921603 0.16859418181494007 0.2307671673690739 1.3495610765469148 0.05150515414243756 0.10738254768121636 1.6522961137307199e-06 5.781912118616664 0.5410121405721764 PKPSS(ph)SPVIFAGGQDR ddPTM_PC-9_AZD4547_30min_R2 1 PKPSSSPVIFAGGQDR 16 1 Q15366-2;Q15366;Q15366-6;Q15366-3;H3BSS4 Q15366-2 PCBP2 Poly(rC)-binding protein 2 1 PKPS(0.075)S(0.604)S(0.321)PVIFAGGQDR 133.52 5.9051999999999996e-05 0.0 18451.0 23404.0 21170.0 14360.0 16502.0 24085.0 22662.0 25736.0 19049.0 19638.0 True False 24318.034195358625 30968.885309835394 20889.271967767734 11049.52385978838 14210.982145254253 22578.961142571476 24678.87409788883 21759.092554446277 20055.891250695735 18950.479597341982 1.2832410953213818 1.63420060958136 1.1023083537525715 0.58307357357532 0.7499009232065822 1.1914717528171914 1.3022822969266867 1.148208014613954 1.0583315924895536 1.0 14.209946740027684 -5.397706935965135 5.922281309452739 1.0081508153621772 1.452913356221367 0.41326705886970383 0.21280043417976893 0.237378848798002 10.366987074472664 0.06305505372258927 0.1333754845530144 4.002147255093871e-06 5.397706935965135 0.44476254085918976 PKPSS(ph)SPVIFAGGQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PKPSSSPVIFAGGQDR 16 1 Q15366-2;Q15366;Q15366-6;Q15366-3;H3BSS4 Q15366-2 PCBP2 Poly(rC)-binding protein 2 1 PKPS(0.006)S(0.592)S(0.402)PVIFAGGQDR;PKPS(0.294)S(0.554)S(0.151)PVIFAGGQDR 63.638999999999996 0.015388999999999998 31438000.0 113197.0 179133.0 125137.0 116159.0 131773.0 79561.0 107473.0 73807.0 76443.0 95164.0 True False 132359.01635733957 196916.14039124537 128120.74066471517 109650.98782255895 105953.02659039557 75388.68110086427 97292.37940286125 71869.64445498075 77560.8342590523 112416.47988219044 1.177398691864826 1.7516661311367192 1.1396971404813812 0.9753995849849626 0.9425043970548767 0.6706194783884859 0.8654636713836009 0.6393159128474604 0.6899418514112348 1.0 16.778494019795694 -5.7551930600985965 1.558933723515943 0.7751552247274502 1.4714411928789424 0.6767063514581703 0.17713436447472186 0.20683078410778122 1.0161604025010584 0.054792496382070954 0.12345488514882419 1.757142325001716e-06 5.7551930600985965 0.6962859681514921 PKPSS(ph)SPVIFAGGQDR ddPTM_PC-9_Lapatinib_30min_R1 1 PKPSSSPVIFAGGQDR 16 1 Q15366-2;Q15366;Q15366-6;Q15366-3;H3BSS4 Q15366-2 PCBP2 Poly(rC)-binding protein 2 1 PKPS(0.09)S(0.903)S(0.007)PVIFAGGQDR 175.19 1.1777999999999999e-28 0.0 11417.0 20781.0 13812.0 14224.0 17777.0 14297.0 17127.0 18914.0 14004.0 14700.0 True False 11254.191486378626 20732.88287128084 12676.430675861826 15270.08040987301 16731.391810926732 13685.550637934788 18013.752256945387 19792.813488951717 12426.722051342427 17240.875413481226 0.6527621838493533 1.2025423520588225 0.7352544677603606 0.8856905489806403 0.9704490873963331 0.7937851361789664 1.044828167069743 1.148016734317043 0.7207709442425152 1.0 14.073545409349082 -7.2755819713312135 24.422262342834077 0.9907386821146393 0.8870630754769273 0.07764443804038823 0.1713931863714504 1662.5196746886152 2870923.5285972883 0.06778901232354041 0.04596879600970049 5.3017351507301234e-08 7.2755819713312135 -0.10367560663771203 PKPSSS(ph)PVIFAGGQDR ddPTM_PC-9_AZD4547_30min_R2 1 PKPSSSPVIFAGGQDR 16 1 Q15366-2;Q15366;Q15366-6;Q15366-3;H3BSS4 Q15366-2 PCBP2 Poly(rC)-binding protein 2 1 PKPS(0.032)S(0.068)S(0.899)PVIFAGGQDR 66.76 0.012342 3495400.0 15362.0 20369.0 21019.0 14168.0 16378.0 14560.0 18855.0 21192.0 19071.0 15581.0 True False 20246.796450550053 26952.880912495184 20740.274326429382 10901.786493417954 14104.197404858462 13649.560898311844 20533.058473025056 17917.26334371406 20079.054125781848 15035.513932487305 1.3465982301278512 1.7926145413797907 1.3794190487639917 0.7250690958998357 0.9380588830012293 0.9078213727579457 1.365637288171386 1.1916628473204463 1.3354418223375086 1.0 13.876086561407414 -5.53091679325868 24.610940226592014 1.0730284836857016 1.5737090324591276 0.494419860551237 0.20975528621710277 120.4561338372401 368811.98257190874 0.05993529157990295 0.10406113875709286 2.9449858113565476e-06 5.53091679325868 0.500680548773426 PKPSSS(ph)PVIFAGGQDR ddPTM_PC-9_Lapatinib_30min_R1 1 PKPSSSPVIFAGGQDR 16 1 Q15366-2;Q15366;Q15366-6;Q15366-3;H3BSS4 Q15366-2 PCBP2 Poly(rC)-binding protein 2 1 PKPS(0.027)S(0.086)S(0.887)PVIFAGGQDR 92.906 0.014049 5708100.0 11329.0 24151.0 16882.0 18742.0 20535.0 17986.0 19651.0 22802.0 17254.0 15513.0 True False 11167.446382515838 24095.079843333024 15494.02712640453 20120.349201479195 19327.17167336335 17216.78070741381 20668.432626918548 23861.46416279353 15310.672827325214 18194.401380226827 0.6137847653868025 1.3243128663479355 0.8515821324708716 1.1058538712543429 1.0622592779758935 0.9462680495838974 1.1359776117383247 1.3114728901565023 0.8415046204248539 1.0 14.151206964942538 -4.739048332371817 24.94581518250674 1.0672220992249122 0.6137829070705298 0.42352873217249676 0.1576693425085487 1722.0764605941035 1918460.4601015765 0.03692761110965723 1.940857898094171 1.8236927333577104e-05 4.739048332371817 -0.45343919215438233 PKS(ph)MS(ph)T(ph)EGLMK ddPTM_PC-9_AZD4547_30min_R2 1 PKSMSTEGLMK 11 1 A0A0C4DGI3;B4DJV2;O75390 A0A0C4DGI3 CS Citrate synthase;Citrate synthase, mitochondrial 3 PKS(1)MS(1)T(1)EGLMK 60.973 0.026226999999999997 0.0 15395.0 11002.0 16559.0 19666.0 14143.0 13776.0 12020.0 9707.8 8435.3 9508.1 True False 20290.289764107405 14558.181344163791 16339.416840541602 15132.307536671204 12179.488575950247 12914.584542248898 13089.756714174557 8207.682573051501 8881.172736993743 9175.2243130404 2.2114216581353308 1.586683970600348 1.7808193329201778 1.649257502638298 1.3274322414810065 1.4075497341131906 1.4266416021644919 0.8945484375119016 0.967951565431623 1.0 13.163527713610323 -5.766052383326473 0.32797709552719184 0.879250628713582 2.4180880448958013 0.81667458208492 0.16595048298202073 1.5732344102156663 0.22238315719712845 0.19047224035603952 0.9172495366393919 1.7137505874728492e-06 5.766052383326473 1.5388374161822194 up PLEGSSSEDSPPEGQAPPS(ph)HSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PLEGSSSEDSPPEGQAPPSHSPR 23 0 Q12789;Q12789-3 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 1 PLEGSSSEDSPPEGQAPPS(0.604)HS(0.396)PR 111.81 0.00029491 0.0 14892.0 15894.0 12668.0 13084.0 15663.0 12217.0 13717.0 12960.0 13286.0 10213.0 True False 17412.921469592813 17471.851280213355 12970.053163657534 12350.945898900332 12593.947587786291 11576.319013200655 12417.626457520011 12619.813732255068 13480.28261535743 12064.536053936483 1.4433146365301988 1.4481991849585085 1.0750561070622848 1.0237398142525669 1.0438816322055806 0.9595328789641663 1.02926680329894 1.0460256139014485 1.1173477832128496 1.0 13.558484816814293 -5.285427189934925 4.416561394050612 1.0323382991382977 1.4525628903043488 0.9490118788686388 0.03799776470747151 0.03730702893707884 1.8295025012455906 0.010454272452258636 0.025193979073484682 5.182899767487491e-06 5.285427189934925 0.42022459116605115 PLEGSSSEDSPPEGQAPPSHS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 PLEGSSSEDSPPEGQAPPSHSPR 23 0 Q12789;Q12789-3 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 1 PLEGSSSEDSPPEGQAPPS(0.324)HS(0.676)PR 70.50399999999999 0.00056195 6093800.0 7093.8 7575.3 9432.8 11328.0 9669.4 8590.4 7133.7 10198.0 8769.7 6766.4 True False 9349.480839793774 10023.867581934548 9307.714908717966 8716.504615855345 8326.970715993304 8053.240930003991 7768.5854801919295 8622.13342672688 9233.24843830261 6529.510395531873 1.4318808415086681 1.5351637373598264 1.4254843540929518 1.3349400012932098 1.27528255743209 1.2333606108529673 1.189765389684953 1.3204869744333332 1.414079751618268 1.0 12.672759102403205 -1.5228787456098167 0.03289455633685118 4.935496667737642e-15 3.3029829024465003 0.6328698706187255 0.08732812867052572 809.8380216712317 2.0465788972785526 62.768742835729626 165.3235651002801 0.029999999977240385 1.5228787456098167 3.3029829024464954 PLEGSSSEDSPPEGQAPPSHS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PLEGSSSEDSPPEGQAPPSHSPR 23 0 Q12789;Q12789-3 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 1 PLEGSSSEDSPPEGQAPPS(0.078)HS(0.922)PR 98.23 4.1603e-06 14510000.0 141720.0 172580.0 158230.0 147690.0 173590.0 140560.0 154710.0 130250.0 117870.0 126110.0 True False 165710.39690241055 189712.60185851378 162002.80329061692 139415.4081174407 139576.28562624147 133188.7861582617 140054.74879659718 126831.07551128247 119593.6257618679 148972.7447137891 1.112353788075653 1.2734718838871855 1.0874660569747947 0.9358450660574842 0.9369249784207144 0.8940480113603866 0.9401367281355697 0.8513710058504602 0.8027886308440831 1.0 17.18468888121133 -5.668935891376754 2.545829887804697 0.9002007491269577 1.194402649785514 0.779179965275057 0.06237756862922887 0.11678884260416171 1.5285110307164715 0.0177905355283005 0.035075155688182466 2.1432069484649507e-06 5.668935891376754 0.29420190065855634 PLEGSSSEDSPPEGQAPPSHS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 PLEGSSSEDSPPEGQAPPSHSPR 23 0 Q12789;Q12789-3 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 1 PLEGSSSEDSPPEGQAPPS(0.072)HS(0.928)PR 116.72 1.5742e-08 17967000.0 21927.0 28850.0 27026.0 26815.0 26761.0 24157.0 19670.0 26343.0 29696.0 23975.0 True False 21614.31695908068 28783.199597538718 24804.026603376904 28787.064552217726 25186.970594150313 23123.861422717408 20688.41635395082 27566.99194984959 26351.323767256836 28119.04680532059 0.7686717515257626 1.0236193209825468 0.8821076608714763 1.0237567706872175 0.8957263298620961 0.8223558068242195 0.7357438713049201 0.9803672272643843 0.9371343185883074 1.0 14.77926006953085 PLISVYSEK ddPTM_PC-9_Lapatinib_30min_R1 2 PLISVYSEK 9 0 P36578;H3BTP7;H3BU31 P36578 RPL4 60S ribosomal protein L4 0 ; 151.44 0.00073344 13841600.0 90047.0 78756.0 61862.0 74873.0 65293.0 53485.0 75861.0 77006.0 68459.0 86890.0 False True 88762.91326740278 78573.64532075427 56775.945154225614 80379.41018900623 61452.59411097704 51197.57122962455 79788.71138927623 80583.97988422414 60748.426514770894 101908.82072635261 0.8710032422585925 0.7710190811818107 0.5571249353054668 0.7887384979641994 0.6030154570818815 0.5023860629994059 0.782942151823406 0.7907458776371251 0.5961056764447668 1.0 16.63691940393285 -10.81854476601652 5.590715107348623 1.000035354177982 0.693682794587826 0.3780878564880281 0.11697514804416871 5.2396139613699065e-05 6.601129215981046e-06 0.11512640684625669 0.02791903852707433 1.5186413961106264e-11 10.81854476601652 -0.30635255959015606 PLLS(ph)PEER ddPTM_PC-9_AZD4547_30min_R2 3 PLLSPEER 8 0 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 PLLS(1)PEER;PLLS(1)PEER;PLLS(1)PEER 86.882 0.012143000000000001 29352900.0 29203.300000000003 38368.0 32604.0 23632.7 31651.8 42471.0 38139.0 49515.0 41944.9 32343.7 True False 38489.341933625066 50769.70567286638 32171.649656924827 18184.546136575267 27257.493919837532 39815.28165605787 41533.29711496701 41863.59449150631 44162.02178178947 31211.356907656107 1.2331838710986538 1.6266420528616183 1.0307674143136392 0.5826259393456431 0.8733197342391513 1.2756664753108262 1.3307110369424198 1.3412936392149366 1.4149343750882097 1.0 14.929783459055614 -6.9230197357478716 11.881314208232173 1.3006047971490022 1.0711580612397704 0.12180606018826823 0.26837435340384636 1.3434015988254755 201.57462673111408 0.10646752131230883 0.09390096358911253 1.1939338470104868e-07 6.9230197357478716 -0.2294467359092318 PLLS(ph)PEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 PLLSPEER 8 0 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 PLLS(1)PEER;PLLS(1)PEER;PLLS(1)PEER;PLLS(1)PEER 116.52 0.0035868000000000002 26409200.0 71386.8 101261.0 77756.8 91822.2 118182.0 81853.1 116736.0 77508.0 94798.0 104137.0 True False 83471.175286431 111313.52286936468 79610.81700630626 86677.69982558898 95025.0854765855 77560.5793418528 105677.92098454881 75473.49712651418 96184.24140980403 123016.21375196152 0.6785379970703255 0.9048687118090541 0.6471571070040094 0.704603866286747 0.7724598455630025 0.6304907050564794 0.8590568491859777 0.6135247933958684 0.7818826354365044 1.0 16.908488952261173 -8.550503134684796 22.44574540756981 1.0000000027045874 0.7295670031181476 0.44794942314214015 0.09090573202468658 1968.234995845022 1599255.4231279432 0.08180995215243857 0.021123238802186726 2.8151196958680926e-09 8.550503134684796 -0.27043299958643985 PLLS(ph)PEER ddPTM_PC-9_Lapatinib_30min_R1 4 PLLSPEER 8 0 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 PLLS(1)PEER;PLLS(1)PEER;PLLS(1)PEER;PLLS(1)PEER 111.61 0.0037431999999999995 31770100.0 28516.6 39501.0 32665.6 26658.9 52157.4 56196.0 62554.0 64631.0 58577.0 63316.0 True False 28109.948054696026 39409.537861434204 29979.960460862458 28619.484437483407 49089.60427739379 53792.62807927422 65792.74004092733 67633.99220706557 51979.44141684415 74260.08623673314 0.37853373836766824 0.5306960960939481 0.40371566988610247 0.3853952491550788 0.6610496535231783 0.7243814383380747 0.8859771564388865 0.910771797267454 0.699964732752118 1.0 16.180299370115588 -6.635782222068701 1.6677298649055132 0.8626908369564057 0.4283764465777856 0.8401313300433141 0.08689320899437018 0.13811215913533967 0.7910857746180353 0.034456211852335425 0.03459979580772372 2.313224470931175e-07 6.635782222068701 -0.4343143903786201 PLPS(ph)PGAAGAQALEK ddPTM_PC-9_AZD4547_30min_R2 2 PLPSPGAAGAQALEK 15 0 H9KVB4;O15417;O15417-2;O15417-3 H9KVB4 TNRC18 Trinucleotide repeat-containing gene 18 protein 1 PLPS(1)PGAAGAQALEK;PLPS(1)PGAAGAQALEK 140.75 7.3995e-05 15077900.0 92341.0 87774.0 113912.0 96856.0 89623.0 108181.0 96192.0 115646.0 100535.0 110230.0 True False 121703.51718788194 116145.22898587823 112401.45245122154 74527.34561028291 77180.39345558865 101416.42496842521 104752.90165140445 97775.56798070786 105849.07485372975 106370.88125140058 1.1441431692216941 1.0918893180115394 1.0566938162857569 0.700636722508131 0.7255782085059338 0.9534228143577579 0.9847892620521574 0.9191948663997784 0.9950944620225757 1.0 16.69874374535422 -5.543626886106587 24.86443009293688 0.8914024335511379 1.1070851246146136 0.4606038321554725 0.10068711746502292 198.40529046372507 237766.54346536854 0.030004288307770258 0.05197518268858212 2.8600466299988367e-06 5.543626886106587 0.2156826910634757 PLPS(ph)PGAAGAQALEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PLPSPGAAGAQALEK 15 0 H9KVB4;O15417;O15417-2;O15417-3 H9KVB4 TNRC18 Trinucleotide repeat-containing gene 18 protein 1 PLPS(1)PGAAGAQALEK;PLPS(1)PGAAGAQALEK 122.5 4.9063e-05 16280500.0 89383.0 89170.0 85184.0 97169.0 99342.0 75017.0 87839.0 73702.0 64252.0 73873.0 True False 104513.77650527921 98022.20829599998 87215.10962211917 91724.93595614826 79876.64823251413 71082.97646011904 79518.25402071139 71767.40059372388 65191.56394715832 87265.59012165372 1.197651632901129 1.123262997011203 0.9994215303023314 1.0511008500404104 0.9153281163991563 0.8145590531276407 0.9112211801909315 0.8224020543913771 0.7470477636864333 1.0 16.413125273415943 -5.624526586283873 0.7114955715915874 0.8417341128134831 1.2315581683352628 0.7239030347057899 0.07134587225972276 0.6121898517791156 0.48342789457313606 0.035289353853061554 0.16264148795435357 2.3739600911422027e-06 5.624526586283873 0.3898240555217797 PLPS(ph)PGAAGAQALEK ddPTM_PC-9_Lapatinib_30min_R1 2 PLPSPGAAGAQALEK 15 0 H9KVB4;O15417;O15417-2;O15417-3 H9KVB4 TNRC18 Trinucleotide repeat-containing gene 18 protein 1 PLPS(1)PGAAGAQALEK;PLPS(1)PGAAGAQALEK 135.08 1.8581e-05 14547700.0 72066.0 93221.0 88881.0 87482.0 91371.0 98703.0 85857.0 77634.0 94140.0 84164.0 True False 71038.32562471417 93005.1525019814 81573.54727058185 93915.71811139715 85996.73742229771 94481.70277793094 90302.25535847255 81241.1590568507 83536.9618618521 98711.63525851928 0.7196550380172455 0.9421903735907832 0.8263822907699391 0.9514148749074823 0.8711914983180848 0.9571485927721649 0.9148086253659651 0.8230150259803258 0.8462726976721062 1.0 16.59093252644415 -4.752688489239213 24.99617122165714 0.8981635271629779 0.7196546987107997 0.4768255520162331 0.05755087809621036 299.2953996996608 854848.1960208835 0.013826940788365076 0.16000528919589113 1.7673050187680124e-05 4.752688489239213 -0.1785088284521782 PLPS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PLPSPPK 7 0 P56945-6;A0A2R8Y6M6;A0A2R8Y5C9;A0A2R8Y8C4;A0A2R8YFS8;A0A2R8Y5E4;A0A2R8Y4C2;A0A2R8YFK2;A0A2R8Y596;P56945;P56945-8;P56945-2;P56945-3;P56945-5;P56945-7;P56945-4 P56945-6 BCAR1 Breast cancer anti-estrogen resistance protein 1 1 PLPS(1)PPK;PLPS(1)PPK 80.219 0.031573000000000004 41061000.0 337937.0 525480.0 273981.0 296221.0 297018.0 168942.0 306122.0 169461.0 180326.0 264941.0 True False 395143.0595400066 577646.1816236633 280513.74611872924 279624.69773143897 238819.45506155357 160082.38411460628 277123.9080286458 165012.8283087713 182962.92660672448 312972.70602819865 1.2625479855882529 1.8456759023952003 0.8962882088940213 0.8934475510022428 0.7630679943063025 0.5114899191886175 0.8854571107669597 0.5272435107932503 0.5845970689541203 1.0 18.255677321387935 -5.407788277609652 4.539182934628962 0.7264793879841633 1.5481577108315252 0.7140254609307415 0.20301710815181437 0.10648663681692659 3.4591311908003592 0.052523890422940346 0.11396954839885222 3.91031480628386e-06 5.407788277609652 0.8216783228473619 PLPTFPT(ph)SECTSDVEPDTR ddPTM_PC-9_Lapatinib_30min_R1 1 PLPTFPTSECTSDVEPDTR 19 0 H0YHZ9;Q8TDD1;Q8TDD1-2 H0YHZ9 DDX54 ATP-dependent RNA helicase DDX54 1 PLPT(0.001)FPT(0.316)S(0.316)ECT(0.316)S(0.051)DVEPDTR 73.46600000000001 0.033002 0.0 2098.9 4211.6 5784.5 4060.9 4964.1 3637.6 5474.2 4715.1 5496.1 3507.9 True False 2068.96930110888 4201.848298959932 5308.920738815724 4359.5521327652805 4672.121397796105 3482.028327659761 5757.627290533689 4934.1807593188205 4877.0713415012215 4114.235841017063 0.5028805788142224 1.0212949527757775 1.2903783215070452 1.0596262103651244 1.1355988276649522 0.8463365889105141 1.3994402637624124 1.1992945834867508 1.185413653947359 1.0 12.00640878074019 -4.782686575862647 3.559355102786241 1.1434384173627916 0.4290115002854736 0.6337663202567069 0.1444969833766943 0.17474469973811071 3.708082561388233 0.036232195496372736 0.3361543896354815 1.649352276141051e-05 4.782686575862647 -0.7144269170773181 PLQKY(ph)MVWS(ph)DEMVK ddPTM_PC-9_Lapatinib_30min_R1 2 PLQKYMVWSDEMVK 14 1 Q9H488 Q9H488 POFUT1 GDP-fucose protein O-fucosyltransferase 1 2 PLQKY(1)MVWS(1)DEMVK;PLQKY(1)MVWS(1)DEMVK 51.135 0.026677 266240000.0 32205.0 12496.2 182392.0 26340.0 87240.0 116258.0 38774.0 55370.0 187433.0 52816.0 True False 31745.750794326294 12467.265816664243 167396.43381348043 28277.131467664163 82108.71472043914 111285.91635063471 40781.52799736092 57942.69233812291 166322.3217830093 61945.17522710372 0.5124814108272333 0.20126290338120265 2.7023320734790204 0.45648642309904525 1.3255062144777499 1.7965227468101868 0.6583487389913335 0.9353866887242327 2.684992352886848 1.0 15.918704297960529 PLRPCRRYSTSGS(ph)S(ph)GLT(ph)T(ph)GK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PLRPCRRYSTSGSSGLTTGK 20 3 D6RAW4;A0A087WYS0;B9A067;Q16891-3;Q16891-2;Q16891-4;Q16891 D6RAW4 IMMT MICOS complex subunit MIC60 4 PLRPCRRY(0.072)S(0.07)T(0.072)S(0.093)GS(0.871)S(0.85)GLT(0.986)T(0.986)GK 50.787 0.041312 2706000.0 6154.9 8455.9 5228.9 5051.4 6196.1 4525.7 3954.8 4995.8 2084.8 3790.5 True False 7196.803005183776 9295.345868903747 5353.576806713676 4768.3864348597635 4982.018684076014 4288.364324960481 3580.1727137275043 4864.665543487645 2115.286255945896 4477.687644418512 1.6072588301586137 2.075925479190247 1.1956119389852862 1.0649216322187214 1.1126320278919315 0.9577185068516281 0.7995583877294857 1.0864236029396792 0.4724059434075586 1.0 12.12853817650473 -5.445697873118865 3.295679049010165 0.9390799508775832 1.8397765247601412 0.7476197240433744 0.20840793660367368 0.11390444335773567 2.365276171251618 0.05550949182530594 0.12574409344632875 3.5834564174497646e-06 5.445697873118865 0.900696573882558 PLRTQS(ph)S(ph)LRPS(ph)PY(ph)PQLCGK ddPTM_PC-9_AZD4547_30min_R2 1 PLRTQSSLRPSPYPQLCGK 19 2 E9PM03 E9PM03 CCDC28B 4 PLRT(0.619)QS(0.691)S(0.691)LRPS(1)PY(1)PQLCGK 48.641000000000005 0.044485000000000004 0.0 8096.9 6210.9 10343.0 13030.0 10539.0 11611.0 6992.0 11449.0 8671.9 9004.6 True False 10671.545774017617 8218.451964230764 10205.845062003851 10026.134811493215 9075.841766381933 10884.962334498541 7614.27445470121 9679.820121847042 9130.278929965267 8689.351694786934 1.2281176028839844 0.9458072653638039 1.1745231888964418 1.1538415250827363 1.044478585419309 1.252678302919749 0.8762764728776368 1.113986458581752 1.0507433984336094 1.0 13.085032827454786 -7.256619537459839 24.98901046550686 1.0197504575219931 1.1234995371859242 0.26170500631273286 0.09989537768715183 652.9911439214256 3385518.4619328394 0.03745219494839672 0.028048230721423373 5.538350825242755e-08 7.256619537459839 0.1037490796639311 PLS(ph)ADLTK ddPTM_PC-9_AZD4547_30min_R2 2 PLSADLTK 8 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 PLS(1)ADLTK;PLS(1)ADLTK 121.9 0.0033521000000000002 23261000.0 144430.0 158550.0 122345.0 101363.0 126305.0 163054.0 163154.0 150845.0 138283.0 138942.0 True False 190355.73566937578 209798.18688576328 120722.62536119716 77995.32639273879 108769.73093299833 152858.207603938 177674.38992882145 127535.37132326119 145592.35706966044 134077.68287065308 1.419742134513281 1.5647509890826425 0.9003931361020032 0.5817174396426745 0.8112441131454387 1.1400719667224768 1.3251600573991633 0.9512050670378652 1.0858806175082527 1.0 17.03270959615903 -5.261545880098887 24.999999505016813 0.9713005576812316 1.4922465979346367 0.5429783237554445 0.18999767684635377 7.568049436957871 1777064.8882131577 0.055994972679337146 0.12990684476882913 5.475882491328542e-06 5.261545880098887 0.5209460402534051 PLS(ph)ADLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PLSADLTK 8 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 PLS(1)ADLTK;PLS(0.999)ADLT(0.001)K 112.85 0.0037234 15289800.0 123887.0 185269.0 119474.0 127441.0 129089.0 87734.0 136996.0 95772.0 94302.0 90714.0 True False 144858.62222021486 203661.28191983473 122322.71326766816 120300.89393929653 103794.93712314032 83133.07459312002 124018.74711485124 93258.08647882193 95680.9883481434 107159.73010837112 1.3518009244117979 1.9005393323953985 1.1414988927646854 1.1226315502813948 0.9686002103418143 0.7757865245558865 1.1573260495284052 0.8702717558593103 0.8928819459640368 1.0 16.709403327174265 -5.447664145124236 4.113046087244369 0.9715130254743707 1.6236866225223503 0.7115083059512501 0.16419824140476466 0.10906422993162408 3.4520286246564735 0.04263183630462581 0.09209531947337969 3.5672689597505147e-06 5.447664145124236 0.6521735970479796 PLS(ph)ADLTK ddPTM_PC-9_Lapatinib_30min_R1 2 PLSADLTK 8 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 PLS(1)ADLTK;PLS(1)ADLTK 125.74 0.0034625 24888000.0 68931.0 135198.0 108350.0 114402.0 137577.0 125868.0 142069.0 158614.0 99589.0 122666.0 True False 67948.0312996026 134884.95733754063 99441.88124309489 122815.50471388426 129484.99134678894 120484.91905263874 149424.6376710443 165983.78548887555 88372.2381013383 143868.65465782932 0.4722921157579955 0.9375562568395798 0.6911990765438305 0.8536640938638308 0.900022257487221 0.8374646954139844 1.038618440037749 1.153717506316048 0.6142563737147526 1.0 17.134392773980714 -4.090841748902173 0.5705545326163026 0.9404523589102486 2.1804534757006043e-16 0.3403179246603544 0.15918368289071289 9.701501124919577 1.3401867594093815 0.07863004177710448 7.170370223807963 8.112566150569699e-05 4.090841748902173 -0.9404523589102484 PLS(ph)PDSR ddPTM_PC-9_Lapatinib_30min_R1 1 PLSPDSR 7 0 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VRN8;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 PLS(0.999)PDS(0.001)R 101.46 0.011192 12196000.0 63791.0 128980.0 95062.0 103480.0 122920.0 97631.0 125580.0 130780.0 94165.0 110640.0 True False 62881.32864216333 128681.35473450736 87246.36930993164 111090.26439916062 115690.08727001822 93455.54971897675 132081.9179323409 136856.51623586254 83559.14609859028 129763.97658146704 0.4845823185966087 0.99165699236814 0.6723466065727228 0.8560947909099959 0.8915424011947329 0.7201964072078546 1.0178627490613208 1.054657231084027 0.6439317621106584 1.0 16.98553041077585 -4.749677204946293 24.862035161770848 0.8674239644432734 0.4845814000059533 0.40152769315690073 0.1418056325290565 515.1071704879703 1088723.5580798422 0.0342025293441612 0.5425281151198925 1.7796016307861813e-05 4.749677204946293 -0.3828425644373201 PLS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PLSPTR 6 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 PLS(1)PTR 93.195 0.034816 19397000.0 68019.0 110820.0 79366.0 59175.0 62150.0 43435.0 61492.0 41096.0 40317.0 52950.0 True False 79533.2732635127 121821.47721613442 81258.38643723128 55859.61659793849 49972.15364750801 41157.19213705254 55667.032596473044 40017.27354481127 40906.5598527296 62549.415848030665 1.2715270348286836 1.9476037555987806 1.2991070393791642 0.8930477741575455 0.798922787207474 0.6579948282338491 0.8899688644850181 0.6397705398566276 0.6539878797927658 1.0 15.93270879060586 -5.679003329667545 2.7031241729905497 0.7628066564243302 1.6168448893722187 0.7615068106540246 0.18859143187468053 0.11049194683881278 1.6285833814339328 0.05095049212554439 0.09775042497032671 2.0940964006813237e-06 5.679003329667545 0.8540382329478885 PLT(ph)SPESLSR ddPTM_PC-9_AZD4547_30min_R2 1 PLTSPESLSR 10 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 PLT(0.944)S(0.056)PESLSR 125.23 0.00094505 6516100.0 33222.0 36476.0 40232.0 37784.0 33579.0 34732.0 32577.0 38911.0 38335.0 38000.0 True False 43785.9049394723 48266.153672942906 39698.49739287818 29073.482556980816 28917.135465730986 32560.202549462032 35476.28988998873 32898.199035827565 40361.309837546396 36669.63156629981 1.1940644906755076 1.3162432130160957 1.0825987526245548 0.7928490501578963 0.7885853833422876 0.8879337249569087 0.967456949379121 0.8971510656262423 1.1006739940806856 1.0 15.162298150367437 -5.519183495147052 4.7027096810638405 0.9106182565387589 1.2475138695969576 0.6807588504881207 0.09221270836330456 0.10343997000874883 6.13486014667838 0.026091714315651736 0.051071263920164284 3.0256347873925248e-06 5.519183495147052 0.3368956130581987 PLT(ph)SPESLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PLTSPESLSR 10 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 PLT(0.539)S(0.459)PES(0.002)LSR 136.49 0.00028226 9301700.0 31995.0 46959.0 28525.0 33417.0 39519.0 29655.0 32768.0 23963.0 32192.0 26151.0 True False 37411.12156994508 51620.7791787806 29205.144181664913 31544.75382937574 31775.53563951519 28099.839595356116 29663.977820224234 23333.996640897232 32662.74709871941 30891.9692887979 1.2110306474864703 1.6710096626147888 0.9453959994792347 1.0211312051515782 1.0286018137094837 0.9096163256107382 0.9602488447047964 0.7553418308414105 1.0573216227611502 1.0 14.914944221788058 -5.278489097578726 24.996106384977136 0.95385400732856 1.4410201399765734 0.6851366731712023 0.13046659443246691 356.9803487862007 523358.4034866038 0.03214097616768117 0.0671705910246369 5.266364352787918e-06 5.278489097578726 0.48716613264801345 PLT(ph)YPQYSPPQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PLTYPQYSPPQPR 13 0 E9PPX2;P15407;E9PKL5 E9PPX2 FOSL1 Fos-related antigen 1 1 PLT(0.758)Y(0.001)PQY(0.002)S(0.239)PPQPR 111.31 0.0014173 6432000.0 28640.0 31283.0 32226.0 31718.0 40968.0 29872.0 29819.0 26129.0 19944.0 24029.0 True False 33488.18633421555 34388.56949785547 32994.390057785575 29940.943291143452 32940.614491248714 28305.45973334944 26994.328449135333 25443.141435963924 20235.643269658933 28385.26748654066 1.1797734987029636 1.2114935860358327 1.1623772815750426 1.0548057475710046 1.1604827929441937 0.9971884093313877 0.9509978534440494 0.8963502439435601 0.7128924636434727 1.0 14.792854716359965 -7.05835881652389 1.0604785727582693 0.8502902473206135 1.1694623564029276 0.7272972691728448 0.07694482200545302 0.2577935024967267 0.5899627853754803 0.04823736782000818 0.03278076396685305 8.742611573073669e-08 7.05835881652389 0.3191721090823141 PLT(ph)YPQYSPPQPR ddPTM_PC-9_Lapatinib_30min_R1 1 PLTYPQYSPPQPR 13 0 E9PPX2;P15407;E9PKL5 E9PPX2 FOSL1 Fos-related antigen 1 1 PLT(0.587)Y(0.002)PQY(0.001)S(0.41)PPQPR 122.46 0.00044385 13218000.0 9056.3 31405.0 28143.0 27312.0 34478.0 30724.0 36563.0 30902.0 29809.0 34307.0 True False 8927.155501277977 31332.283652017435 25829.191175121603 29320.61559016112 32450.07182635605 29410.00614114211 38456.05323586702 32337.819733297318 26451.596517314076 40236.91923879594 0.22186478662289144 0.7786948962485983 0.6419276540987615 0.7286993175633224 0.8064750592303819 0.7309209228122352 0.9557404981141838 0.8036852807090059 0.6573961679404563 1.0 15.296232228205353 -4.761376789659866 9.914761107707152 0.7807152656898322 0.2194504459778355 0.7074311175107021 0.10934610029250838 0.040512166568072355 81.59048559064092 0.026751663746370898 0.1516944674059442 1.7323004186429432e-05 4.761376789659866 -0.5612648197119967 PLTS(ph)PESLSR ddPTM_PC-9_AZD4547_30min_R2 2 PLTSPESLSR 10 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 PLT(0.012)S(0.984)PES(0.004)LSR;PLT(0.048)S(0.94)PES(0.013)LSR 171.67 0.00011124 23447000.0 128711.0 144405.0 121532.0 119631.0 111404.0 131820.0 126385.0 151296.0 136528.0 119437.0 True False 169638.42064488627 191081.09225631444 119920.40627240171 92051.9212305253 95937.47757301584 123577.27456150211 137633.02015981317 127916.67963620984 143744.59135256367 115255.54698379338 1.4718460419847725 1.6578906374300861 1.040474054487497 0.7986767113557594 0.8323892435867408 1.0722024040966887 1.1941552815602565 1.1098526967573787 1.2471815466961973 1.0 16.814476660348987 -5.268259589945747 24.585128625834816 1.0318596966865565 1.5648683527861413 0.6979283938015179 0.13891440806769695 224.56764850391605 809512.6707086415 0.0407358966403231 0.08799853532604592 5.391882383010889e-06 5.268259589945747 0.5330086560995848 PLTS(ph)PESLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 PLTSPESLSR 10 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 PLT(0.045)S(0.954)PES(0.001)LSR;PLT(0.099)S(0.901)PESLSR;PLT(0.228)S(0.772)PESLSR;PLT(0.031)S(0.964)PES(0.006)LSR 169.21 0.00041448 26448600.0 152564.0 268338.0 174084.0 158251.0 174851.0 114982.0 156102.0 112976.0 122255.0 117153.0 True False 178390.07192364743 294976.82325593824 178234.82277724607 149384.70952666458 140590.2017284059 108952.14150575743 141314.8884793897 110010.49970796666 124042.74809126314 138391.91151736208 1.289020940369534 2.131459996626549 1.2878991324206506 1.079432373530901 1.0158845281269782 0.7872724663687354 1.0211210101080286 0.7949200101493301 0.8963150138705993 1.0 17.078400099819007 -5.6137441129862955 2.6417271699108213 0.9244119534314669 1.7150988017570215 0.6702924003545989 0.2134474118115083 0.13908104883522923 1.9496121232864394 0.05697038024325825 0.11667610570884768 2.4336374898871694e-06 5.6137441129862955 0.7906868483255546 PLTS(ph)PESLSR ddPTM_PC-9_Lapatinib_30min_R1 3 PLTSPESLSR 10 0 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 PLT(0.171)S(0.829)PESLSR;PLT(0.171)S(0.827)PES(0.001)LSR;PLT(0.228)S(0.772)PES(0.001)LSR 89.35600000000001 0.0094013 32736700.0 49584.0 93158.0 90399.0 75710.0 91191.0 83139.0 85911.0 97232.0 85484.0 80948.0 True False 48876.923067408046 92942.29837461057 82966.74317023133 81277.96596115618 85827.32466840411 79583.33877647477 90359.05121424858 101749.75368286743 75855.89173357289 94939.75394356997 0.5148204101777994 0.9789608095029756 0.8738883315364908 0.8561004488116322 0.9040188235522278 0.838250948320103 0.9517514788163022 1.071729696533079 0.7989897654322962 1.0 16.534724690272647 -4.7559566598083425 24.99999981830719 0.916150341716012 0.5148197759187071 0.7042991666390734 0.07860184070022201 96.7627842679543 441170.5410779815 0.019246236054784226 0.16286136728976838 1.7540555381667726e-05 4.7559566598083425 -0.40133056579730486 PLTS(ph)PLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PLTSPLR 7 0 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 PLT(0.119)S(0.881)PLR;PLT(0.12)S(0.88)PLR 113.41 0.0090265 9440300.0 98126.0 145792.0 108950.0 106362.0 115344.0 86430.0 111092.0 90451.0 79271.0 89899.0 True False 114736.79372315762 160265.2662542388 111547.781195176 100402.8819702566 92743.17120383211 81897.4586486808 100568.56152357039 88076.75709075616 80430.18840900178 106196.97705990759 1.0804148752598917 1.5091320929392402 1.05038565393674 0.9454401127973497 0.8733127229366807 0.7711844622703431 0.9470002283288901 0.8293716029324498 0.7573679650375519 1.0 16.696383174262955 -5.58412372757751 2.7853535749252196 0.8632465799118304 1.2963427679465873 0.6452313144289088 0.12276357222377612 0.14218427688023666 2.2181118766536834 0.03262505250152506 0.0674768570027721 2.605411180130518e-06 5.58412372757751 0.4330961880347569 PLTS(ph)PLR ddPTM_PC-9_Lapatinib_30min_R1 1 PLTSPLR 7 0 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 PLT(0.129)S(0.871)PLR 93.195 0.014078 21567000.0 32055.0 67192.0 63159.0 62243.0 64944.0 67360.0 71911.0 77418.0 70030.0 66831.0 True False 31597.889821832927 67036.4210522642 57966.31082079045 66820.55785656118 61124.12160481666 64479.16982382934 75634.1997167747 81015.12290830429 62142.483951407376 78382.64930328989 0.40312352418160347 0.8552456653114241 0.7395298747366719 0.8524916987432903 0.7798169894501276 0.8226204446641868 0.964935484945393 1.0335849021232804 0.7928091803959875 1.0 16.258246715849154 -4.5498395364249555 2.093495455642812 0.8731540432308027 4.203229883920347e-38 0.6852918857503121 0.09449786190111366 1.052360285838783 2.842954015337912 0.02611843250583123 2.1914543469838477 2.819424462710574e-05 4.5498395364249555 -0.8731540432308027 PLTYPQYS(ph)PPQPR ddPTM_PC-9_AZD4547_30min_R2 1 PLTYPQYSPPQPR 13 0 E9PPX2;P15407;E9PKL5 E9PPX2 FOSL1 Fos-related antigen 1 1 PLT(0.003)YPQYS(0.997)PPQPR 146.84 0.00010621 15450000.0 19505.0 27248.0 28043.0 15577.0 24286.0 30921.0 24568.0 32405.0 36397.0 26966.0 True False 25707.184270796693 36055.383136318385 27671.13149702932 11985.963312250955 20914.308106874607 28987.504981916263 26754.50440547758 27397.55184282061 38320.871114051806 26021.928547811607 0.9879046521691651 1.3855769018069406 1.0633774297776406 0.46061010774925637 0.8037186048085379 1.1139645137621461 1.0281522507572782 1.0528640024693592 1.472637627285873 1.0 14.6674402671724 -8.027758481906389 15.15155178589039 1.2451504326380987 0.9799305158956082 0.1470381882830173 0.24585766234347528 11.638156468705755 6345.512152862425 0.17494167434150998 0.06759521033092379 9.380835451277496e-09 8.027758481906389 -0.26521991674249046 PLTYPQYS(ph)PPQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 PLTYPQYSPPQPR 13 0 E9PPX2;P15407;E9PKL5 E9PPX2 FOSL1 Fos-related antigen 1 1 PLT(0.138)Y(0.001)PQY(0.008)S(0.853)PPQPR;PLT(0.002)YPQYS(0.998)PPQPR;PLT(0.008)YPQY(0.005)S(0.986)PPQPR 150.9 0.0001182 31669800.0 51585.0 78223.0 66545.0 60471.0 65574.0 38334.0 59231.0 52637.0 56133.0 44739.0 True False 60317.32164980827 85988.46248220265 68131.68517331773 57083.00591962717 52725.24542689767 36323.69755684981 53620.21088469547 51255.33452351154 56953.838931797254 52849.82654627086 1.141296492184312 1.6270339583218574 1.2891562683496673 1.0800982642705572 0.9976427336187355 0.6873002227367357 1.0145768565153215 0.9698297586395422 1.0776542262051374 1.0 15.689611116223718 -5.820575826700034 2.4185906152714955 0.9491033905606107 1.3978419727906384 0.5922478542787306 0.1469859850727442 0.18330013390614272 2.1848992238293747 0.04360420001040459 0.07659953055766386 1.5115557625699855e-06 5.820575826700034 0.4487385822300277 PLTYPQYS(ph)PPQPR ddPTM_PC-9_Lapatinib_30min_R1 2 PLTYPQYSPPQPR 13 0 E9PPX2;P15407;E9PKL5 E9PPX2 FOSL1 Fos-related antigen 1 1 PLT(0.011)YPQY(0.004)S(0.985)PPQPR;PLT(0.001)Y(0.037)PQY(0.101)S(0.861)PPQPR 115.1 0.00033360000000000003 16874000.0 15474.7 41186.0 39030.8 37432.0 46693.0 34930.0 44939.0 42334.0 37334.0 41604.0 True False 15254.027940287584 41090.63634746032 35821.83828724501 40184.87414949147 43946.60954197006 33436.12532580699 47265.72153178428 44300.99218786517 33129.05177555114 48795.19596615462 0.3126133144514493 0.8421041361522895 0.7341263330941799 0.8235416080174071 0.9006339388912866 0.6852339592815447 0.9686552250875021 0.9078965933161387 0.6789408489829645 1.0 15.574451496661982 -4.760804811417375 24.99901080582603 0.8326089567184581 0.31261271854119693 0.6889075319251798 0.10584349998304178 8.50509144006339 334802.1460967021 0.025078588520213118 0.14510554212738558 1.7345834108472027e-05 4.760804811417375 -0.5199962381772611 PMESLDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PMESLDLK 8 0 B0QY29;Q9NWS6 B0QY29 FAM118A Protein FAM118A 0 70.525 0.02862 0.0 45578.0 41309.0 42711.0 56675.0 58485.0 51618.0 59525.0 56438.0 49346.0 40893.0 False True 53293.45519346635 45409.88451832978 43729.39222236951 53499.68349282909 47025.28408808539 48911.0612117043 53886.36107631983 54956.562301003934 50067.59189653979 48306.57719119012 1.1032339340156294 0.9400352324405916 0.9052471685024422 1.1075030897156188 0.9734758043809736 1.0125134931030557 1.115507746761808 1.137662105172432 1.0364549675788421 1.0 15.55993201240146 -7.164662493897085 6.125857569823987 1.083593335443906 1.0016253392240386 0.16584906150385492 0.06971914087047316 0.35648760118972117 18.70522600273051 0.026749820095801385 0.020635005108347638 6.844433465746298e-08 7.164662493897085 -0.08196799621986739 PMFIVNTNVPR ddPTM_PC-9_Lapatinib_30min_R1 1 PMFIVNTNVPR 11 0 P14174 P14174 MIF Macrophage migration inhibitory factor 0 121.73 0.0034038000000000002 3399800.0 15148.0 9091.1 9765.3 8756.2 8876.5 7515.4 6833.9 6795.3 9151.2 10505.0 False True 14931.98674219702 9070.050116505521 8962.434729148094 9400.160157826916 8354.401721870452 7193.983861253074 7187.725903470487 7111.034445462284 8120.495489591887 12320.775252967363 1.2119356481728507 0.7361590427778536 0.727424577198546 0.7629520030050837 0.6780743541165041 0.5838905193502705 0.5833826001930664 0.5771580358751894 0.6590896532777942 1.0 13.5888054162984 -2.4151778155101167 1.2156809068938816 0.666688904964684 199.99999999061612 0.6082096983706682 0.12127240864586672 336.5844134838194 1.8199279024857737 0.034308790203849436 185623.53769549317 0.0038443434880876108 2.4151778155101167 199.33331108565145 PMGS(ph)SQEEGLR ddPTM_PC-9_AZD4547_30min_R2 1 PMGSSQEEGLR 11 0 A0A669K9N4;Q6ZVT0 A0A669K9N4 TTLL10 Inactive polyglycylase TTLL10 1 PMGS(0.5)S(0.5)QEEGLR 72.089 0.024748 7168800.0 0.0 0.0 806.3 3174.7 2352.7 1572.9 1309.0 895.6 1613.3 1490.3 True False 0.0 0.0 795.6079351729394 2442.821963626058 2026.0682155580964 1474.546314351284 1425.4984641309898 757.205598840615 1698.575744382772 1438.1250506120155 0.0 0.0 0.5532258372346387 1.6986158210556714 1.4088261759266854 1.0253255193098605 0.9912201053200121 0.5265227794470133 1.1811043439233033 1.0 10.4899734138843 -5.504805190877529 4.66830772935322 1.1062878517735006 0.04089927139912489 0.7088360516744081 0.2881480545370275 0.11327791298893881 6.36656977425994 0.08672458870991714 0.17391245530835756 3.127481930153164e-06 5.504805190877529 -1.0653885803743757 PMGS(ph)SQEEGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PMGSSQEEGLR 11 0 A0A669K9N4;Q6ZVT0 A0A669K9N4 TTLL10 Inactive polyglycylase TTLL10 1 PMGS(0.5)S(0.5)QEEGLR;PMGS(0.5)S(0.5)QEEGLR 83.182 0.011551 2492700.0 8580.6 8848.8 10279.300000000001 13731.6 14858.5 12372.5 14264.4 11334.0 12116.7 9110.8 True False 10033.126105424937 9727.250384318111 10524.397496462341 12962.262970447857 11947.083587634721 11723.664319458549 12913.172766687207 11036.494509365648 12293.883814955698 10762.515918946878 0.9322286889966048 0.9038082226846018 0.977875208336246 1.2043896676267334 1.1100641966626474 1.089305178059678 1.1998284475430325 1.025456741944181 1.1422871666385108 1.0 13.393727751078071 -5.588979346449708 5.957865051645288 1.1136821264285655 0.9230831999057483 0.6267303545799838 0.061937425889881076 0.11231342811297652 7.366314018088208 0.01603111022756081 0.028261776709845192 2.5764436808799623e-06 5.588979346449708 -0.19059892652281718 PMGS(ph)SQEEGLR ddPTM_PC-9_Lapatinib_30min_R1 2 PMGSSQEEGLR 11 0 A0A669K9N4;Q6ZVT0 A0A669K9N4 TTLL10 Inactive polyglycylase TTLL10 1 PMGS(0.5)S(0.5)QEEGLR;PMGS(0.5)S(0.5)QEEGLR 91.12299999999999 0.007365100000000001 22349000.0 2905.0 2045.85 3929.7999999999997 4105.71 4225.4 3488.2 2376.2 4042.3999999999996 3701.8599999999997 2314.6 True False 2863.5741672882446 2041.112960021649 3606.7070134666806 4407.657609647055 3976.8702794560236 3339.0178173913514 2499.228009164105 4230.224661506736 3284.9175444860366 2714.6755259893635 1.054849516958243 0.7518810040024085 1.3285959883372125 1.6236406772926149 1.4649523456423594 1.2299878145379626 0.9206359969128397 1.5582800305259432 1.2100589971204196 1.0 11.40656405358639 -5.274024676484939 23.982601886042413 1.3144983305573523 0.9033652728607224 0.3240009058086536 0.22266903863108498 428.93099824491196 817374.3770903602 0.05937227327417065 0.12509717468669115 5.320780258906806e-06 5.274024676484939 -0.4111330576966299 PMGSS(ph)QEEGLR ddPTM_PC-9_AZD4547_30min_R2 1 PMGSSQEEGLR 11 0 A0A669K9N4;Q6ZVT0 A0A669K9N4 TTLL10 Inactive polyglycylase TTLL10 1 PMGS(0.445)S(0.555)QEEGLR 83.314 0.011422 7872400.0 0.0 1277.8 2988.0 3035.4 3063.3 1652.2 1577.1 3233.1 1131.9 3449.5 True False 0.0 1690.823861259087 2948.3771676754836 2335.6354264625106 2638.0136714069426 1548.8876728153048 1717.4588447524707 2733.4986842469766 1191.7299231803513 3328.7340549460864 0.0 0.507948016678212 0.885735273232345 0.7016587651368681 0.7924975765147658 0.46530832660357757 0.515949552112924 0.8211826595715378 0.35801295733120775 1.0 11.700757897424209 -14.522878745255559 0.0555260887018763 2.2217028878653315 1.2807963606018288e-16 0.2266855659804934 0.24716147789219742 875.4379625227199 3.557954092716293 159.58389396360326 30.19234329293002 3.000000000171164e-15 14.522878745255559 -2.2217028878653315 PMGSS(ph)QEEGLR ddPTM_PC-9_Lapatinib_30min_R1 1 PMGSSQEEGLR 11 0 A0A669K9N4;Q6ZVT0 A0A669K9N4 TTLL10 Inactive polyglycylase TTLL10 1 PMGS(0.439)S(0.561)QEEGLR 77.593 0.017022 11828000.0 1363.3 2795.7 0.0 1624.4 1492.8 1636.9 0.0 759.2 1070.1 0.0 True False 1343.8590920013999 2789.2267284172945 0.0 1743.863794839548 1404.9964389577208 1566.8936028002713 0.0 794.4752035958621 949.5740693474379 0.0 0.0 PMVIS(ph)SGMQS(ph)MDTMK ddPTM_PC-9_Lapatinib_30min_R1 1 PMVISSGMQSMDTMK 15 0 Q9NR45;Q5TBR1 Q9NR45 NANS Sialic acid synthase 2 PMVIS(0.512)S(0.512)GMQS(0.754)MDT(0.222)MK 42.785 0.045038999999999996 19457000.0 10441.0 10241.0 12837.0 10366.0 12229.0 10182.0 9217.1 10198.0 14401.0 11507.0 True False 10292.109425355105 10217.287593705163 11781.591412252988 11128.350219962293 11509.71426313905 9746.539595401275 9694.316338383334 10671.836309629349 12779.00773074709 13495.969617886296 0.762606149595573 0.757062136548094 0.872971097729708 0.8245684107953102 0.8528260354028325 0.7221815009485589 0.7183119562995602 0.7907424669573867 0.9468758520181453 1.0 13.720241010497546 -8.342863107924437 3.5196845714654086 0.9951352421067187 0.7878417387013401 0.703464111244821 0.0487639911232219 0.14180138297191375 3.1678410290238306 0.05112427072442216 0.013815290671711358 4.54084724166659e-09 8.342863107924437 -0.20729350340537855 PMY(ph)S(ph)KPS(ph)IMAHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PMYSKPSIMAHK 12 1 O43298 O43298 ZBTB43 Zinc finger and BTB domain-containing protein 43 3 PMY(1)S(1)KPS(1)IMAHK 50.897 0.042970999999999995 0.0 3150.4 1766.2 3074.6 5048.0 5005.1 3163.0 3175.9 3631.1 1647.9 4141.1 True False 3683.7004967637113 1941.536663590841 3147.9101244854337 4765.176925836815 4024.386584410981 2997.126711856732 2875.0557604751625 3535.787472468468 1671.9974199794901 4891.848649070438 0.7530283050485828 0.3968922186420827 0.6435011281642182 0.9741055514344882 0.8226719330688421 0.612677727146414 0.5877237761682361 0.7227916736835976 0.34179254918224167 1.0 12.256164053079035 -5.5200590036577415 24.997547505435236 0.7134138909277876 0.5612693428219668 0.08251290552847779 0.19747317341433188 264.77051872796886 2347238.980608242 0.05344104118731712 0.09478398047184224 3.0195414547843977e-06 5.5200590036577415 -0.1521445481058208 PMYFLLSQLSLMDMMLVS(ph)T(ph)TVPK ddPTM_PC-9_AZD4547_30min_R2 1 PMYFLLSQLSLMDMMLVSTTVPK 23 0 Q8NG77 Q8NG77 OR2T12 Olfactory receptor 2T12 2 PMYFLLS(0.001)QLS(0.001)LMDMMLVS(0.966)T(0.957)T(0.075)VPK 59.975 0.022517 0.0 8164.9 9319.3 12354.0 16155.0 16036.0 15160.0 12183.0 16337.0 12786.0 15256.0 True False 10761.168359529762 12331.581476155747 12190.177888039794 12430.714342261925 13809.678201508745 14212.042803462062 13267.26339840171 13812.492036912841 13461.841856863652 14721.892083564991 0.730963676302393 0.837635638555067 0.8280306511449357 0.844369342724577 0.9380369128588701 0.9653679515371459 0.9011928170029735 0.9382280455874709 0.9144097633952897 1.0 13.84567548057452 -2.762867447525089 0.3087243568935848 0.9655615051785831 1.234772650810242e-12 0.8246187320174786 0.03164299231473678 11.041773850312417 0.313750160416462 0.033316667041521544 5.124143216182583 0.0017263647211531127 2.762867447525089 -0.9655615051773483 PNNSGEAPS(ph)SPTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PNNSGEAPSSPTPK 14 0 P49916-4;P49916-3;P49916-2;P49916;K7ENR9;K7ERZ5 P49916-4 LIG3 DNA ligase 3 1 PNNS(0.005)GEAPS(0.873)S(0.116)PT(0.005)PK 147.75 0.00020773 6046800.0 28624.0 43418.0 22648.0 25845.0 22802.0 16485.0 26232.0 16793.0 14008.0 17396.0 True False 33469.47785022997 47728.25210043434 23188.014213018305 24396.98844062052 18334.111785526587 15620.497579816061 23747.115056766434 16352.201543654259 14212.84049946762 20549.75709333978 1.628704305272664 2.3225701347050554 1.1283838591227724 1.187215417185035 0.8921814356369552 0.7601305216828426 1.1555910344294495 0.7957369748644884 0.6916305839972207 1.0 14.326833720302867 -5.396896512437795 4.539611757299624 0.933314782992045 1.9685544756861524 0.7803319082996839 0.21894030425492475 0.09262529409432126 2.9684142150960042 0.05761659384486573 0.1254484252823291 4.009622511055582e-06 5.396896512437795 1.0352396926941074 PNNSGEAPSS(ph)PTPK ddPTM_PC-9_AZD4547_30min_R2 3 PNNSGEAPSSPTPK 14 0 P49916-4;P49916-3;P49916-2;P49916;K7ENR9;K7ERZ5 P49916-4 LIG3 DNA ligase 3 1 PNNSGEAPS(0.239)S(0.757)PT(0.003)PK;PNNSGEAPS(0.3)S(0.691)PT(0.009)PK;PNNSGEAPS(0.021)S(0.942)PT(0.037)PK 135.86 3.3868e-05 4175700.0 68681.0 79575.0 57200.0 42296.7 47774.0 65149.0 73136.0 68498.0 69174.0 57236.0 True False 90520.12934645402 105296.062576062 56441.49062618394 32545.849292500774 41141.40473926659 61075.22273105213 79644.96231679466 57913.208027450295 72830.39641848007 55232.185061282566 1.6389018331615508 1.9064257997258545 1.0218949433841809 0.5892551463678235 0.7448809909225639 1.1057904492332948 1.4420027422131685 1.0485409542134358 1.318622399922645 1.0 15.753221583089502 -5.267615863860761 24.581316933987623 1.026551154734095 1.7726638414899456 0.6042229088888933 0.2391119335898071 254.68664163824045 1013612.4625947482 0.0696978321044527 0.15126309998632695 5.399880340832037e-06 5.267615863860761 0.7461126867558505 PNNSGEAPSS(ph)PTPK ddPTM_PC-9_Lapatinib_30min_R1 2 PNNSGEAPSSPTPK 14 0 P49916-4;P49916-3;P49916-2;P49916;K7ENR9;K7ERZ5 P49916-4 LIG3 DNA ligase 3 1 PNNSGEAPS(0.038)S(0.817)PT(0.145)PK;PNNSGEAPS(0.008)S(0.925)PT(0.067)PK 153.2 1.3189e-08 7258100.0 21224.0 69511.0 44159.0 54538.0 64774.0 54564.0 66383.0 69585.0 47350.0 59765.0 True False 20921.34186799509 69350.05155024328 40528.41747866945 58548.90645343466 60964.12067058379 52230.42491489645 69819.98692548646 72818.17313253187 42016.944382395304 70095.30061814323 0.2984699642272435 0.9893680594657861 0.5781902227576611 0.8352757736555033 0.8697319240086695 0.7451344734140039 0.9960722945728332 1.0388452933417316 0.5994259816544646 1.0 16.097030104781606 -4.751980105135327 24.992370544799222 0.8443556891976626 0.29846888530585897 0.525114031774721 0.15732254723371705 302.8871372765319 800202.0116766669 0.03797447149334517 0.474584952749106 1.770190048191412e-05 4.751980105135327 -0.5458868038918037 PNPS(ph)STSSPYPLPEEIR ddPTM_PC-9_AZD4547_30min_R2 1 PNPSSTSSPYPLPEEIR 17 0 O75563 O75563 SKAP2 Src kinase-associated phosphoprotein 2 1 PNPS(0.58)S(0.332)T(0.009)S(0.04)S(0.04)PYPLPEEIR 79.471 0.006367800000000001 10119000.0 12955.0 15873.0 19909.0 25207.0 19196.0 18667.0 20039.0 21327.0 20712.0 15843.0 True False 17074.420519260253 21003.63683656716 19644.99365169048 19395.915594267823 16530.966747079183 17499.749539065066 21822.43217931315 18031.402195705454 21806.794035613955 15288.341392233888 1.1168262194834064 1.3738335832320243 1.2849656576657602 1.2686736315373284 1.081279278305266 1.1446467010446615 1.4273904290493162 1.1794217392911552 1.426367548718613 1.0 13.90014427905436 -6.0507428093073425 24.996555830075025 1.2217604280176384 1.2711965845755158 0.0251644056082585 0.13976897151771456 1695.8091166950608 835373.2796153905 0.040606467544740094 0.052423306819502774 8.897278617864998e-07 6.0507428093073425 0.049436156557877364 PNPSS(ph)TSSPYPLPEEIR ddPTM_PC-9_AZD4547_30min_R2 1 PNPSSTSSPYPLPEEIR 17 0 O75563 O75563 SKAP2 Src kinase-associated phosphoprotein 2 1 PNPS(0.148)S(0.442)T(0.05)S(0.267)S(0.089)PY(0.003)PLPEEIR 94.61 0.0017315000000000002 8778000.0 20978.0 24770.0 30991.0 38844.0 30398.0 21672.0 29472.0 27788.0 21828.0 28436.0 True False 27648.567630493348 32776.418096249494 30580.039090840313 29889.11593381753 26177.76240767416 20316.846414025702 32094.950905170776 23494.0031047153 22981.78351725481 27440.464295244783 1.0075838124679481 1.1944556674986506 1.1144140551637676 1.0892350658584549 0.9539839459717363 0.7403973269339489 1.1696212775354744 0.8561809615148029 0.8375143827736681 1.0 14.744017271802896 -6.272691136608502 4.041893808512494 0.9199613934747917 1.1114960093458561 0.36338353284419234 0.11400449055078991 0.2327436836766907 9.044803179908184 0.03524318645499681 0.04281315961075506 5.337143297683332e-07 6.272691136608502 0.19153461587106446 PNPSS(ph)TSSPYPLPEEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PNPSSTSSPYPLPEEIR 17 0 O75563 O75563 SKAP2 Src kinase-associated phosphoprotein 2 1 PNPS(0.055)S(0.854)T(0.055)S(0.018)S(0.018)PYPLPEEIR 124.84 3.9693e-05 4126400.0 12662.0 9802.8 6028.0 12207.0 11336.0 18856.0 28422.0 19751.0 20687.0 21198.0 True False 14805.426514100469 10775.957199551745 6171.730381317304 11523.08136562797 9114.792176156887 17867.158165909113 25729.662402539467 19232.557177914336 20989.508239041028 25041.029596724326 0.5912467159911509 0.43033203398958375 0.24646472132777808 0.46016803427025743 0.36399430546375033 0.7135153168081538 1.0275001793818104 0.7680417893212422 0.8382046815593682 1.0 14.612006261450606 -6.919321561697983 3.8516834305809424 0.8886585125408837 0.41262329479140747 0.8220990970945987 0.10756799275833927 0.09412528293085339 2.727018801895693 0.04028907235072578 0.034858547808275624 1.2041440340729398e-07 6.919321561697983 -0.4760352177494762 PNPSS(ph)TSSPYPLPEEIR ddPTM_PC-9_Lapatinib_30min_R1 1 PNPSSTSSPYPLPEEIR 17 0 O75563 O75563 SKAP2 Src kinase-associated phosphoprotein 2 1 PNPS(0.063)S(0.723)T(0.063)S(0.117)S(0.034)PYPLPEEIR 130.09 2.8863e-05 7038800.0 12515.0 11963.0 15659.0 9823.9 12532.0 22072.0 21078.0 18596.0 22470.0 22921.0 True False 12336.533805030076 11935.300408504534 14371.577465488015 10546.382377569706 11794.89239885997 21128.032012345033 22169.315704553923 19460.038048035633 19939.19198041019 26882.864309687295 0.45889953030728875 0.443974283060441 0.5345999332485262 0.3923087307987972 0.4387513273505479 0.785929347741844 0.8246634528659643 0.72388261250209 0.7417063803437441 1.0 14.71439924181897 -6.768178698011115 10.801725834298672 0.7987197844975962 0.45418110527627464 0.8424373798580453 0.0780124469682882 0.07287666829578929 102.99142025656103 0.02591712321129685 0.02385914376664816 1.7053805361630318e-07 6.768178698011115 -0.34453867922132153 PNPSST(ph)SSPYPLPEEIR ddPTM_PC-9_Lapatinib_30min_R1 1 PNPSSTSSPYPLPEEIR 17 0 O75563 O75563 SKAP2 Src kinase-associated phosphoprotein 2 1 PNPS(0.014)S(0.16)T(0.41)S(0.41)S(0.006)PYPLPEEIR 205.98 6.7184e-17 4908900.0 17311.0 20345.0 24167.0 21884.0 38094.0 47429.0 44355.0 57185.0 57685.0 49391.0 True False 17064.141965551407 20297.89240249307 22180.082547317765 23493.42236288394 35853.38581568558 45400.572232399056 46651.48486931819 59842.02386410615 51187.90785002052 57928.168540629325 0.2945741665142246 0.3503976202571751 0.3828894147026455 0.4055612831330281 0.6189283507304212 0.7837391268559831 0.8053333299601565 1.033038422786222 0.8836445055934858 1.0 15.821977432974156 -6.649300400406967 0.8698399457316695 0.9764929192926044 0.3069588564812629 0.9640111636227602 0.050678400998834264 0.09459585394471276 0.15715989057572288 0.02912273596585358 0.03070665627116725 2.2423303729317893e-07 6.649300400406967 -0.6695340628113415 down PNS(ph)VAAT(ph)S(ph)S(ph)T(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 PNSVAATSSTK 11 0 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 5 PNS(1)VAAT(1)S(1)S(1)T(1)K 56.729 0.033176 0.0 870.03 2110.2 2838.5 1165.1 2543.5 2645.0 2868.2 3554.0 2403.8 3051.2 True False 857.6232126560384 2105.3139615503014 2605.1294869268604 1250.7853406596635 2393.896330713401 2531.879515796148 3016.701361789617 3719.131814514877 2133.0587308638196 3578.5958545315593 0.23965355338184782 0.5883072711002982 0.7279753268668204 0.3495184679979439 0.6689485004801593 0.7075064127708193 0.8429846466092509 1.0392712576932535 0.5960602475305328 1.0 11.805177908163387 -6.8178032627814575 1.5526888644682466 0.874105511301037 0.5006950389592739 0.511405016233762 0.16828798299776196 0.33379968647492936 1.6683914631264787 0.0751520039458131 0.06514683213035964 1.5212365001709338e-07 6.8178032627814575 -0.37341047234176306 PPFADEEEEEEMLLR ddPTM_PC-9_AZD4547_30min_R2 1 PPFADEEEEEEMLLR 15 0 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 0 89.663 0.0018774 1220900.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 False True 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPPEQDS(ph)GR ddPTM_PC-9_AZD4547_30min_R2 1 PPPEQDSGR 9 0 B5MCA9;Q8N7S2 B5MCA9 DNAJC5G DnaJ homolog subfamily C member 5G 1 PPPEQDS(1)GR 82.494 0.015693000000000002 3837000.0 15799.0 11737.0 26870.0 25296.0 31514.0 30447.0 26804.0 31045.0 26016.0 22755.0 True False 20822.753360385377 15530.755720455396 26513.686243453903 19464.398019304095 27138.825071236373 28543.14427684759 29189.50407377161 26247.708593129646 27391.152647283325 21958.354376082963 0.9482838742718133 0.7072823151707349 1.207453244872148 0.8864233487599014 1.2359225380202434 1.2998762925484424 1.3293120046174687 1.1953404223095445 1.2474137259173559 1.0 14.422482318117318 -5.809356760707186 1.0844841125316231 1.2370280805655758 0.8447236569388349 0.44684712092728596 0.14610476006815207 0.4720760934974676 1.0835693068356604 0.05349435794993131 0.14191292625709737 1.5511122913174496e-06 5.809356760707186 -0.3923044236267409 PPSPPLGLCHS(ph)PRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PPSPPLGLCHSPRR 14 1 A0A087WYA1;Q9UKN7 A0A087WYA1 MYO15A Unconventional myosin-XV 1 PPSPPLGLCHS(1)PRR 68.847 0.045641 3574900.0 26787.0 25123.0 29689.0 32767.0 32220.0 24057.0 28719.0 34908.0 24866.0 20950.0 True False 31321.510032633807 27617.04540787721 30396.898356159512 30931.17122204734 25906.722293205265 22795.40857007189 25998.528412445663 33991.70198808332 25229.61820814975 24748.069159891264 1.2656142921806601 1.1159272761624426 1.2282533299778877 1.249841796635065 1.0468179204538433 0.9210984672297581 1.0505275480068965 1.373509253124807 1.0194580451972763 1.0 14.595028350312875 -6.263832633675498 24.912633269946586 1.0789684468721248 1.2087921933129087 0.26941111151130015 0.1171382588760963 342.4186630214853 3564408.741720874 0.03805360308119915 0.04516993932120871 5.44712531101608e-07 6.263832633675498 0.12982374644078387 PPYTVVYFPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PPYTVVYFPVR 11 0 P09211;A8MX94;A0A2R8Y5E5 P09211 GSTP1 Glutathione S-transferase P 0 92.051 0.036204 2672500.0 5237.3 5012.0 6009.2 4748.7 6579.6 7291.5 7819.2 6255.2 5690.7 6272.3 False True 6123.871448609886 5509.558236845939 6152.482118017907 4482.645734493121 5290.374612053801 6909.12090404785 7078.508769894331 6091.007627932242 5773.915721753311 7409.418338500518 0.8264982713675748 0.743588495768608 0.8303596634635447 0.6049929332779849 0.7140067371502256 0.9324781768829217 0.9553393325240217 0.822062859682574 0.7792670703651763 1.0 12.855144575762939 -6.757885432929086 24.998076983960985 0.8903027886641328 0.7409599523584919 0.4585937801586998 0.08340093634358521 93.30443050752234 656293.6806062757 0.029227029693175772 0.028129545238190445 1.7462827623063144e-07 6.757885432929086 -0.14934283630564094 PPYTVVYFPVR ddPTM_PC-9_Lapatinib_30min_R1 1 PPYTVVYFPVR 11 0 P09211;A8MX94;A0A2R8Y5E5 P09211 GSTP1 Glutathione S-transferase P 0 143.04 0.00067709 11382000.0 16895.0 15029.0 17038.0 12971.0 11808.0 9704.9 12935.0 10471.0 14154.0 15365.0 False True 16654.07420183645 14994.201273879002 15637.20140858195 13924.930609987548 11113.476655421204 9289.84405022686 13604.711008558927 10957.520886264847 12559.827471772396 18020.819777424436 0.9241574138985522 0.832048789071348 0.8677297482421659 0.7727134937241862 0.6167020586568209 0.5155061847888132 0.7549440689486399 0.6080478591762996 0.6969620487247038 1.0 14.137377021218319 -5.969077728598161 3.3594898353593505 0.6732418732129556 0.8699406125861933 0.27612165102352326 0.12296898612916395 0.26761357517142004 6.315735715217125 0.034761324488796146 0.05204708822242955 1.0737972104484635e-06 5.969077728598161 0.19669873937323767 PQCVMANGQEVSEALCDHLQK ddPTM_PC-9_Lapatinib_30min_R1 1 PQCVMANGQEVSEALCDHLQK 21 0 P82987-2;P82987 P82987-2 ADAMTSL3 ADAMTS-like protein 3 0 49.395 0.041042 29343000.0 6167.0 8586.8 9237.5 7374.6 13869.0 6184.7 6871.1 5765.0 6376.5 8370.7 False True 6079.05744911071 8566.917792171414 8478.028407781181 7916.952684944426 13053.25268750311 5920.194798239862 7226.851937449493 6032.8629461672135 5658.31142247822 9817.564341743357 0.6192022010248643 0.8726113212974514 0.8635572034637354 0.806407007823956 1.3295815777852265 0.603020728172644 0.7361145479558102 0.6144969094336413 0.5763457437624946 1.0 13.261149432629887 PQFDT(ph)TATAVIMT(ph)RLST(ph)RDK ddPTM_PC-9_AZD4547_30min_R2 1 PQFDTTATAVIMTRLSTRDK 20 2 A2PYH4 A2PYH4 HFM1 Probable ATP-dependent DNA helicase HFM1 3 PQFDT(0.462)T(0.462)AT(0.114)AVIMT(0.506)RLS(0.506)T(0.95)RDK 50.376000000000005 0.03659 0.0 4447.5 5333.6 4788.9 6580.3 6730.8 6691.9 4630.4 5810.7 4835.9 6055.2 True False 5861.712486253177 7057.581895767312 4725.396056988326 5063.31349962155 5796.344602065047 6273.454435124526 5042.496629726608 4912.789831602462 5091.515801314479 5843.209291059437 1.0031666151719143 1.2078263064384769 0.8086987512527657 0.8665295469338762 0.9919796319693535 1.0736316504567784 0.8629669721811982 0.8407691025408607 0.871356055841589 1.0 12.51254524907186 -7.287903700946098 24.730676919107424 0.8805037742921954 0.9877514514322357 0.15793592510395493 0.1091182359797584 1263.8639147318202 1181064.1433943284 0.04820951297706643 0.03251432872719212 5.153429023822583e-08 7.287903700946098 0.10724767714004035 PQPGEGPGGPGGPPEVS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 PQPGEGPGGPGGPPEVSR 18 0 M0R0J1;Q9H4M7-2;Q9H4M7 M0R0J1 PLEKHA4 Pleckstrin homology domain-containing family A member 4 1 PQPGEGPGGPGGPPEVS(1)R 97.12899999999999 0.00079177 5283600.0 2367.2 0.0 17325.0 28682.0 24609.0 13281.0 4945.4 22371.0 6507.2 15862.0 True False 3119.9203591812334 0.0 17095.259180046087 22069.808032482615 21192.465132260466 12450.536970499968 5385.5310194907515 18914.07598443881 6851.157307287908 15306.676208017052 0.20382742254305597 0.0 1.116849860003718 1.4418419604984714 1.3845242980419656 0.8134056539315082 0.351841964009797 1.2356749255943846 0.44759275065213266 1.0 13.901873420139886 -5.260293522187053 24.993885992077075 0.9858029773713971 0.10191363996625705 0.5055747977703176 0.34479438184359873 81.79269648916048 1784038.976158244 0.09469923587353483 0.22362074115718292 5.491695867488804e-06 5.260293522187053 -0.8838893374051401 PQQAAGMLS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PQQAAGMLSPK 11 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 PQQAAGMLS(1)PK;PQQAAGMLS(1)PK 76.52199999999999 0.01807 9977300.0 91795.0 146051.0 79264.0 106629.0 87177.0 63625.0 94932.0 84037.0 57363.0 67530.0 True False 107334.08046610761 160549.97806256686 81153.9543703941 100654.9228258822 70095.29265533082 60288.392994588845 85939.3537118385 81831.11779456165 58201.825354865854 79772.6544328142 1.3454996731556184 2.0125941552789195 1.0173154566235882 1.2617722644625717 0.8786882316216039 0.7557526250472797 1.0773034233706988 1.0258041226831824 0.7295961977031159 1.0 16.283606663901473 -5.335061215614157 7.649109857052575 0.9708233525661945 1.6769599735402578 0.6491406251836641 0.20906288988375957 0.15124078206558855 14.034027111266527 0.05342169864169879 0.11206583004690178 4.623158514635985e-06 5.335061215614157 0.7061366209740634 PQS(ph)GAEIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PQSGAEIK 8 0 O43683-2;O43683-3;O43683;A0A590UK50 O43683-2 BUB1 Mitotic checkpoint serine/threonine-protein kinase BUB1 1 PQS(1)GAEIK 74.533 0.027651 5490900.0 56168.0 77968.0 53933.0 79028.0 73589.0 52333.0 72935.0 54157.0 54308.0 51597.0 True False 65676.13303143227 85708.14776743903 55218.967262041515 74600.31737223292 59169.7637130566 49588.56535301872 66026.06879632724 52735.43613408467 55102.15175935804 60951.1276583727 1.0775212133816938 1.4061782129418163 0.9059548097541429 1.223936623295357 0.9707738968292673 0.8135791290189012 1.0832624650752856 0.8652085393672047 0.9040382660055478 1.0 15.895365291979722 -5.98127003179537 1.0353690011210708 0.9281494698108004 1.2093701373408692 0.33677637513716263 0.13954932061034248 0.6034963406981255 1.3101524261271176 0.054932847856863885 0.11832049486288887 1.0440708441926354e-06 5.98127003179537 0.2812206675300688 PQSPVIQAAAVS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 PQSPVIQAAAVSPK 14 0 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 1 PQSPVIQAAAVS(1)PK;PQS(0.001)PVIQAAAVS(0.999)PK 132.62 1.2703e-05 11369100.0 56819.0 66257.0 47937.0 37040.0 44803.0 47079.0 62539.0 46532.0 52783.0 50239.0 True False 74886.26009138155 87673.27952374656 47301.32405852059 28501.000262295398 38582.876806073626 44135.142687611486 68104.8498459038 39341.54859898562 55573.001621369825 48480.1479015615 1.544678870275673 1.8084367172675786 0.9756844008513651 0.5878901260814308 0.7958489913111612 0.9103755784167057 1.4047987226480843 0.8114981142150861 1.1463042921034463 1.0 15.56510647969125 -5.269915518287667 23.371608451381203 0.9431289323410376 1.6765578099513396 0.6446964273771078 0.21442550723063206 140.06683488835455 386214.8854908315 0.058688970153617 0.12576017284954813 5.371362733569047e-06 5.269915518287667 0.7334288776103021 PQSPVIQAAAVS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 PQSPVIQAAAVSPK 14 0 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 1 PQSPVIQAAAVS(1)PK;PQSPVIQAAAVS(1)PK;PQSPVIQAAAVS(1)PK;PQSPVIQAAAVS(1)PK 149.09 1.9989e-05 20908400.0 75595.0 119997.0 65013.0 72520.0 70440.0 40298.7 72908.0 49650.0 42534.9 58993.0 True False 88391.7404306921 131909.50912745428 66563.15648317548 68456.93951301239 56637.78765777091 38185.365230193136 66001.62643179038 48346.740108523445 43156.89244437503 69687.96391166894 1.268393212674869 1.8928592790378056 0.9551600125316587 0.9823351934888369 0.8127341434391825 0.5479477816082264 0.9471022358387301 0.6937602620992633 0.6192876075282866 1.0 16.088621883499695 -5.413306193932536 4.7120063952512785 0.7949480816266524 1.5750935070779113 0.7000442927329276 0.20083095771722834 0.11015869110667804 3.807764899836484 0.05191367116452313 0.11188854456949789 3.860946698184865e-06 5.413306193932536 0.7801454254512589 PQSPVIQAAAVS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 PQSPVIQAAAVSPK 14 0 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 1 PQSPVIQAAAVS(1)PK;PQSPVIQAAAVS(1)PK;PQSPVIQAAAVS(1)PK 164.59 5.7718e-05 16288100.0 52394.0 88225.0 57793.0 82927.0 75844.0 71685.0 88138.0 82905.0 59597.0 65625.0 True False 51646.85195211716 88020.72043302772 53041.48262743143 89025.72821636237 71383.00503504113 68619.19965589666 92701.35437745384 86757.06895958248 52884.55827576794 76968.19381018417 0.6710155116733872 1.1435986226999277 0.6891350829699887 1.1566560654380693 0.9274351066504561 0.8915266977048019 1.2044111962152855 1.1271807829288452 0.6870962622065641 1.0 16.231974771953567 -5.767772394117065 24.999968523870788 1.0055613109318242 0.8654846302497481 0.13513738085640936 0.18546848981112468 337.8753851341315 1333789.495457749 0.050352596208504255 0.076796649138531 1.7069767502643087e-06 5.767772394117065 -0.14007668068207613 PQT(ph)SPSPK ddPTM_PC-9_AZD4547_30min_R2 2 PQTSPSPK 8 0 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 1 PQT(0.966)S(0.032)PS(0.002)PK;PQT(0.493)S(0.493)PS(0.014)PK 115.23 0.008907 139647000.0 485020.0 448330.0 282420.0 226130.0 247950.0 354740.0 389360.0 316020.0 524260.0 585620.0 True False 639246.2709572826 593243.9049290087 278674.92627005005 173999.22217367342 213526.4224285417 332558.0517216453 424012.2857097342 267186.3704171624 551971.3133019981 565117.6220488552 1.1311738406593503 1.049770670357404 0.4931272984546184 0.30789912645589196 0.37784421171364935 0.5884758123732606 0.7503080229076236 0.4727978034881804 0.9767370398056343 1.0 19.108191651850767 -10.53289757956834 12.019922324916982 1.0000157014887194 0.6613124830702316 0.1025376782807097 0.27449349697484093 0.0 0.0 0.2875390524787166 0.06973846381528048 2.9315845244698457e-11 10.53289757956834 -0.33870321841848783 PQT(ph)SPSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PQTSPSPK 8 0 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 1 PQT(0.699)S(0.278)PS(0.023)PK;PQT(0.658)S(0.311)PS(0.032)PK 108.43 0.0092769 91495000.0 146241.0 422560.0 234010.0 162361.0 418540.0 276450.0 192419.0 217600.0 283110.0 420430.0 True False 170996.7129085896 464508.9641982478 239589.6858878671 153264.4395514645 336530.09151452925 261952.47533758866 174191.67932707904 211888.23056625784 287249.9481585006 496650.63087795145 0.34429980005524424 0.9352831453714548 0.48241091622965165 0.30859608348937784 0.677599242992262 0.5274381205849343 0.350732826049476 0.42663437312400787 0.5783742741868989 1.0 18.92187181849917 -8.56633157945057 18.77374326165384 1.0000000035930348 0.5139390960046054 0.4103329410069857 0.17626495572319836 739.1245405945361 319338.9172787066 0.17076545065474633 0.044091449760375906 2.714366086420922e-09 8.56633157945057 -0.48606090758842935 PQT(ph)SPSPK ddPTM_PC-9_Lapatinib_30min_R1 3 PQTSPSPK 8 0 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 1 PQT(0.493)S(0.493)PS(0.014)PK;PQT(0.476)S(0.476)PS(0.049)PK;PQT(0.726)S(0.267)PS(0.007)PK 115.23 0.008907 164593000.0 208133.0 790250.0 401810.0 557890.0 769700.0 432220.0 971070.0 1018130.0 529950.0 635340.0 True False 205164.9852530821 788420.2246778149 368774.7328314546 598919.0916664827 724427.7592884225 413734.95815403067 1021347.2531179977 1065436.0366662997 470261.45037910016 745157.6724626655 0.27533097065891304 1.0580582523859297 0.4948949013873722 0.8037481378768065 0.9721805009324633 0.5552314274463301 1.370645825523819 1.4298128785887003 0.6310898589085676 1.0 19.507186200967375 -7.256196652256834 24.993257242520418 1.1437048821597902 0.7185097421177912 0.3152620191542953 0.29610197340181915 513.1888681818988 2446493.646446329 0.11127240520293263 0.08355534438969268 5.5437463054063354e-08 7.256196652256834 -0.425195140041999 PQTS(ph)PSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PQTSPSPK 8 0 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 1 PQT(0.28)S(0.653)PS(0.067)PK 87.568 0.011628 76272000.0 109480.0 256960.0 145400.0 109560.0 247650.0 176220.0 109340.0 125540.0 167210.0 236520.0 True False 128012.80167143588 282469.2906105211 148866.88743257092 103421.70839831227 199124.7602704003 166978.71298241967 98982.5236469519 122244.70802062482 169655.12991975903 279399.20370871003 0.4581716768416301 1.0109881734130202 0.5328107076059291 0.3701574915944837 0.712689075799942 0.5976348921756581 0.3542691687487662 0.43752704516678603 0.607214078164068 1.0 18.0919683834908 -11.380557330645868 6.359319338146362 1.0539433085874583 0.5664842200894982 0.33761748870126573 0.18293818295607386 0.09980889234559194 0.002233718398206474 0.12635862970688075 0.04425261255792905 4.163347575912396e-12 11.380557330645868 -0.48745908849796016 PQTS(ph)PSPK ddPTM_PC-9_Lapatinib_30min_R1 1 PQTSPSPK 8 0 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 1 PQT(0.467)S(0.491)PS(0.041)PK 115.91 0.0036131 104780000.0 53091.0 222690.0 111460.0 167580.0 211920.0 132710.0 268630.0 278010.0 146690.0 178050.0 True False 52333.912604302976 222174.37498703235 102296.1890480421 179904.39223049214 199455.28225075058 127034.30266211981 282538.34698331525 290927.35952540307 130168.22748581987 208825.70526328817 0.2506104913584283 1.0639225410823545 0.4898639701423094 0.8615050144505345 0.9551280193177208 0.6083269418482486 1.3529864373118718 1.3931587548506101 0.6233343128026472 1.0 17.671939784875782 -4.627447779744796 0.40074230664395266 1.0800982677520548 2.782404686745346e-13 0.27095263458945573 0.2988737306150838 9.129292827352065 1.0539275179365926 0.24507223793036378 4.873096144960775 2.358045714060746e-05 4.627447779744796 -1.0800982677517765 PQVIADY(ph)ES(ph)GRAIPNNQVLGK ddPTM_PC-9_AZD4547_30min_R2 1 PQVIADYESGRAIPNNQVLGK 21 1 O60869-2;O60869-3;O60869 O60869-2 EDF1 Endothelial differentiation-related factor 1 2 PQVIADY(1)ES(1)GRAIPNNQVLGK 50.493 0.011878 7690300.0 71394.0 44679.0 35595.0 29403.0 34523.0 35899.0 39550.0 15579.0 21111.0 22513.0 True False 94095.80691254874 59120.613004534964 35122.98704264018 22624.59262182157 29730.077360357096 33654.22985497921 43069.87338149782 13171.623519805651 22226.884361039316 21724.826722423888 4.331256958446767 2.7213387595635905 1.616721159225036 1.0414164822069198 1.3684839810331082 1.5491138449561053 1.9825186148454774 0.6062936053805296 1.0231098569866712 1.0 14.407057049675583 -4.849867682124391 1.5063100534918015 1.2495997179966316 5.2863585934402 0.8842691578081235 0.35285675426999863 0.32317931919070736 0.7620055965940441 0.10840053030400557 1.889748411361113 1.4129679724778502e-05 4.849867682124391 4.036758875443568 up PRAS(ph)Y(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 PRASYSPR 8 1 Q8NH08 Q8NH08 OR10AC1 Olfactory receptor 10AC1 2 PRAS(0.989)Y(0.992)S(0.019)PR 71.221 0.042858 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRDIVVEPMGGY(ph)MYWTDWGASPK ddPTM_PC-9_Lapatinib_30min_R1 1 PRDIVVEPMGGYMYWTDWGASPK 23 1 O75096 O75096 LRP4 Low-density lipoprotein receptor-related protein 4 1 PRDIVVEPMGGY(0.486)MY(0.432)WT(0.078)DWGAS(0.004)PK 48.229 0.038721 0.0 44222.0 22944.0 30054.0 25545.0 38569.0 49233.0 50295.0 49244.0 60123.0 56981.0 True False 43591.386170678394 22890.874577675146 27583.076131794904 27423.664515621917 36300.4472495715 47127.41935772848 52899.029004674994 51532.0560140604 53351.31461674238 66830.08992759013 0.6522718466772873 0.34252347411887707 0.41273438598812223 0.4103490590142141 0.5431751968148292 0.7051826416632189 0.7915450818933607 0.7710906280373852 0.7983127760945421 1.0 16.02821019505032 -6.846188080893739 1.524541706041624 0.8326541743523793 0.4404327855005941 0.7746309225881636 0.09511159688264127 0.18110836386688775 0.8714448077345357 0.04303841892059764 0.036389973075826317 1.4249903361648e-07 6.846188080893739 -0.3922213888517852 PRHY(ph)RAPS(ph)HDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PRHYRAPSHDK 11 2 Q96R30 Q96R30 OR2V2 Olfactory receptor 2V2 2 PRHY(1)RAPS(1)HDK 112.02 0.0015949999999999998 23500000.0 11930.0 19057.0 195340.0 35545.0 101120.0 98395.0 39755.0 54792.0 93756.0 33066.0 True False 13949.513371759493 20948.85301667461 199997.646431075 33553.52888844483 81306.26189599365 93234.99298550209 35989.11859872479 53353.76805692278 95127.0041310742 39060.60404968803 0.35712487584714925 0.5363166680685759 5.120188263772443 0.8590120328339576 2.081541334910386 2.3869316733274313 0.9213661558572909 1.3659227591322645 2.4353695096487877 1.0 15.25342663939246 -7.254592572249175 24.29804888667347 1.461158181070514 1.9372909724115324 0.027317443014525877 1.3205438156844063 1817.328514190362 6449378.020352906 0.5220186430991253 0.39488098064739197 5.5642601636153506e-08 7.254592572249175 0.47613279134101827 PRIS(ph)S(ph)T(ph)HLS(ph)RR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PRISSTHLSRR 11 2 A0A5F9ZHQ8 A0A5F9ZHQ8 4 PRIS(1)S(1)T(1)HLS(1)RR 71.221 0.034141000000000005 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRPAT(ph)STPDLASHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PRPATSTPDLASHR 14 1 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 PRPAT(0.434)S(0.283)T(0.283)PDLASHR 78.441 0.0087 4446200.0 18810.0 19424.0 22472.0 22113.0 21542.0 21392.0 25658.0 20023.0 20043.0 19391.0 True False 21994.161485565455 21352.286351256087 23007.81770553457 20874.08030131328 17320.9997405409 20270.16586153627 23227.488492166543 19497.417466122148 20336.090957369317 22906.434800928444 0.9601739282742502 0.9321523203772695 1.004425957399622 0.9112758263222704 0.7561630559740726 0.8849114250077309 1.014015873444657 0.8511764329790805 0.8877894414431117 1.0 14.483465311990772 -5.979955121707708 19.548517791208738 0.8908960721172111 0.9615099512744574 0.14656327278140457 0.07038728161177506 36.438601321994 35531.361142756075 0.020340374236049265 0.03015153349345348 1.0472367598084565e-06 5.979955121707708 0.07061387915724626 PRPATST(ph)PDLASHR ddPTM_PC-9_AZD4547_30min_R2 2 PRPATSTPDLASHR 14 1 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 PRPAT(0.205)S(0.141)T(0.654)PDLASHR;PRPAT(0.192)S(0.116)T(0.692)PDLASHR 93.76799999999999 0.002261 29814000.0 78145.0 66419.0 89208.0 110938.0 93537.0 84951.0 73602.0 103993.0 82386.0 109118.0 True False 102993.48448302523 87887.64285566389 88025.0436325283 85362.95807501428 80551.0021161465 79639.0005406928 80152.43541403285 87923.27137140682 86740.7557656475 105297.81203293451 0.9781160927713431 0.8346578258261894 0.8359627036219544 0.8106812138538537 0.7649826768570668 0.7563215132692759 0.7611975393084444 0.8349961853329548 0.8237659842211836 1.0 16.68411593357319 -4.175541877986886 1.426254766311462 0.809013099848459 1.5117240528827518 0.30319838074893024 0.06714835242409975 6.398132501385036 3.48034998449401 0.0180532508616523 9.846755193403734 6.67510531403427e-05 4.175541877986886 0.7027109530342928 PRPATST(ph)PDLASHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PRPATSTPDLASHR 14 1 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 PRPAT(0.154)S(0.118)T(0.728)PDLASHR;PRPAT(0.294)S(0.294)T(0.411)PDLASHR 63.894 0.026685000000000004 20660900.0 54110.0 52893.0 57502.0 71163.0 64040.0 51585.0 66698.0 55951.0 57198.0 53759.0 True False 63269.75427878505 58143.867482340866 58873.065757549375 67175.96782355879 51491.8217149865 48879.79178979747 60379.88258829695 54482.34553498478 58034.41254201517 63505.081143990115 0.9962943616327095 0.9155781936646401 0.9270607122611464 1.0578046136378503 0.8108299491537536 0.7696989108472821 0.9507882125430694 0.8579210443248254 0.9138546317329969 1.0 15.954584408410073 -6.2721704637043 24.99830554736876 0.8743843236650168 0.9666323282483387 0.26646072836987167 0.07197823255368704 978.8507196122362 2280251.2374376724 0.022269803837311003 0.025498059310585026 5.343545802179855e-07 6.2721704637043 0.09224800458332183 PRPATST(ph)PDLASHR ddPTM_PC-9_Lapatinib_30min_R1 2 PRPATSTPDLASHR 14 1 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 PRPAT(0.158)S(0.104)T(0.738)PDLASHR;PRPAT(0.171)S(0.171)T(0.658)PDLASHR 92.264 0.0026292 30816000.0 72866.0 66472.0 62820.0 58963.0 58150.0 59441.0 47262.0 45692.0 56814.0 50454.0 True False 71826.91747801223 66318.08816802746 57655.18209221257 63299.33571480191 54729.73132729871 56898.84699373871 49708.99510525794 47815.01712684688 50415.009042057136 59174.906674270904 1.2138070258967115 1.120713016635181 0.974318090767364 1.0696989530246999 0.9248807375152998 0.9615367423718842 0.8400350401713651 0.8080286022256917 0.8519660084901739 1.0 15.8526979052128 -4.962913814488901 0.5124747143462228 0.8647344096695431 1.3944180312096137 0.7261889372624302 0.06446153234730188 1.897587724049766 0.43762133140826204 0.04135814374456556 0.5920961108999142 1.0891462123803328e-05 4.962913814488901 0.5296836215400706 PRPEAEPPSPPS(ph)GDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PRPEAEPPSPPSGDLR 16 1 F8WDP1;A0A0A0MRY0;Q8WUA7-3;Q8WUA7-4;Q8WUA7;B0QYI1;Q8WUA7-2 F8WDP1 TBC1D22A TBC1 domain family member 22A 1 PRPEAEPPS(0.249)PPS(0.751)GDLR 75.334 0.0058545 4843900.0 19851.0 31591.0 22205.0 22454.0 24067.0 16176.0 23226.0 15219.0 17404.0 21513.0 True False 23211.38222487826 34727.145702354355 22734.451412931438 21195.975176850214 19351.244116405072 15327.702083779477 21025.86513832178 14819.517375863412 17658.50057486682 25413.1366031857 0.913361565213818 1.3665037198911167 0.8945944677321542 0.834055847092608 0.761466182571862 0.6031409000437219 0.8273620634332108 0.5831439702726695 0.6948571855019743 1.0 14.63328682981643 -5.601389680047024 2.51712250918053 0.7314804763960003 1.1408756939527689 0.4743718188532666 0.15550560871320565 0.20547268279521114 2.613989307760622 0.04193105475789388 0.088523197974744 2.5038616012331054e-06 5.601389680047024 0.40939521755676855 PRPVS(ph)PSSLLDTAISEEAR ddPTM_PC-9_Lapatinib_30min_R1 1 PRPVSPSSLLDTAISEEAR 19 1 A0A0B4J2F2;P57059 A0A0B4J2F2 LOC102724428;SIK1 Serine/threonine-protein kinase SIK1 1 PRPVS(0.991)PS(0.006)S(0.003)LLDTAISEEAR 70.944 0.018844999999999997 0.0 6754.8 6243.1 5733.9 5944.5 8301.6 6275.5 3987.1 5275.7 6321.3 6499.8 True False 6658.475313321393 6228.644485524918 5262.480875494074 6381.678360270683 7813.316209573565 6007.111493905003 4193.532528969868 5520.828281889741 5609.3286277599855 7623.281769560908 0.873439486378176 0.8170555246160973 0.6903169834947852 0.8371300646071042 1.0249281668652794 0.7879954690761752 0.5500954386487815 0.7242062472272666 0.7358154660054073 1.0 12.896196486241584 -7.0030446524748955 24.999699016690425 0.7209034666258106 0.8443018394297014 0.09174250454516542 0.12856264541578377 230.43996695370544 1892160.2357610143 0.045845279928720555 0.039668459180088024 9.930139453280989e-08 7.0030446524748955 0.12339837280389077 PRS(ph)PPLPAVIR ddPTM_PC-9_AZD4547_30min_R2 2 PRSPPLPAVIR 11 1 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 PRS(1)PPLPAVIR;PRS(1)PPLPAVIR 100.22 0.0031815000000000003 0.0 10663.099999999999 9048.4 12082.1 10649.5 11741.3 12577.3 14522.0 13337.2 11398.3 12331.2 True False 14053.743993741711 11973.118348893982 11921.883459696095 8194.42230813485 10111.223164590583 11790.839442742961 15814.429867158313 11276.242198366519 12000.79086790935 11899.488441325171 1.1810376608237316 1.0061876531862584 1.001882015221188 0.6886365198420487 0.8497191467051469 0.9908694395462507 1.3290008175676802 0.9476241145968755 1.0085131749220724 1.0 13.538611932996377 -7.008513203230308 24.850136159623283 1.0802077571694495 0.9359841746257865 0.1309088460887341 0.15132567161017918 746.1757674019988 2178097.994889951 0.05841070452737106 0.04906165005086874 9.80588502447356e-08 7.008513203230308 -0.14422358254366296 PRS(ph)PPLPAVIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PRSPPLPAVIR 11 1 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 PRS(1)PPLPAVIR 94.54700000000001 0.0051662 0.0 7257.8 9025.8 7877.2 9100.4 8193.4 7650.2 9141.7 7269.5 5970.6 7455.7 True False 8486.402191915842 9921.821774565866 8065.022322447354 8590.53409189488 6587.96208681403 7249.010044592593 8275.731995823486 7078.68332767193 6057.908729734535 8807.35939071127 0.9635580672302385 1.1265376299995171 0.9157140028773181 0.9753813499372961 0.7480065016720063 0.8230628186057448 0.9396382762070016 0.8037236830754859 0.6878234963505113 1.0 13.10449382197326 -5.845270416101218 1.7729498940089259 0.8307076786574157 1.034229343733663 0.3822967260886103 0.09820846153170679 0.342473366699928 2.1965306140418455 0.03063521070009036 0.058427230068305094 1.4280045259291006e-06 5.845270416101218 0.20352166507624725 PRS(ph)PPLPAVIR ddPTM_PC-9_Lapatinib_30min_R1 1 PRSPPLPAVIR 11 1 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 PRS(1)PPLPAVIR 78.814 0.014787999999999999 0.0 10796.0 8953.9 6636.7 6020.3 8232.5 8334.5 4939.3 6445.3 6075.2 5720.0 True False 10642.047060256073 8933.167794675972 6091.056144402851 6463.052945132064 7748.280535717738 7978.052863668429 5195.0327858194905 6744.772167724459 5390.947001307877 6708.6943785790945 1.5863067326835159 1.331580675846501 0.9079346592164987 0.9633846141163674 1.1549610249735103 1.189210957223272 0.7743731481355396 1.0053777660912027 0.8035761799674772 1.0 12.711816306403746 -5.042054691971391 2.999295859924489 0.9818352628876914 1.5741703320161171 0.7170175106858574 0.12605160394934095 0.1479333658768415 2.5059875549775974 0.034705474593469954 0.1548837229200292 9.077062128880784e-06 5.042054691971391 0.5923350691284257 PS(ph)HPLAK ddPTM_PC-9_Lapatinib_30min_R1 1 PSHPLAK 7 0 F8VWT9;J3KPF0;Q9Y4D8-2;Q9Y4D8-4;Q9Y4D8 F8VWT9 HECTD4 Probable E3 ubiquitin-protein ligase HECTD4 1 PS(1)HPLAK 65.305 0.0324 2373600.0 41977.0 43945.0 45281.0 42229.0 53200.0 42899.0 39100.0 40454.0 51507.0 45673.0 True False 41378.400282360984 43843.24805247276 41558.17096971469 45334.661531814396 50070.88059522426 41064.30977245332 41124.406682230656 42333.64052458775 45705.739267244666 53567.51719455295 0.7724532039085914 0.8184670551976038 0.7758091684327785 0.8463088062708324 0.9347246842404664 0.7665897529525407 0.7677116438469621 0.7902856570864641 0.8532360964433925 1.0 15.70907080956044 -8.659578648914444 3.9281180202861026 0.9999811807065446 0.8111938946546177 0.5813951559303363 0.048618226806363164 0.64757960001427 17.48917283645453 0.049959070754585194 0.013093422546961723 2.1898852131029374e-09 8.659578648914444 -0.18878728605192696 PS(ph)MSPTPLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PSMSPTPLDR 10 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 PS(0.867)MS(0.066)PT(0.066)PLDR;PS(0.866)MS(0.107)PT(0.027)PLDR 105.2 0.0021974 110375000.0 377810.0 613430.0 409553.0 361276.0 339901.0 264908.0 375486.0 249300.0 257995.0 273331.0 True False 441765.7709123591 674327.276382364 419318.2967584009 341034.8769925952 273299.83904974477 251015.75813611853 339917.24779677443 242756.13915518372 261767.68879641214 322883.74661299435 1.3681883202434952 2.0884522167992765 1.2986664741009468 1.0562156831057732 0.8464341792258735 0.7774183766424881 1.0527542849786002 0.7518375938760061 0.8107180728120224 1.0 18.300655294543233 -5.631161212362649 2.4700817091638805 0.8758565146438395 1.7299069420423008 0.7442007243967264 0.19428125458064185 0.12311663638990196 1.5121491117694246 0.05248259585407692 0.1083603204968532 2.3379692112721734e-06 5.631161212362649 0.8540504273984613 PS(ph)S(ph)S(ph)S(ph)KT(ph)SDPLASK ddPTM_PC-9_Lapatinib_30min_R1 1 PSSSSKTSDPLASK 14 1 A0A3B3IRW6;Q2KHR3-2;Q2KHR3;H0YCQ7 A0A3B3IRW6 QSER1 Glutamine and serine-rich protein 1 5 PS(0.995)S(0.995)S(0.995)S(0.945)KT(0.816)S(0.248)DPLAS(0.005)K 44.391000000000005 0.043724 5620200.0 11673.0 10113.0 55489.0 12894.0 34003.0 48233.0 16123.0 25728.0 67232.0 14911.0 True False 11506.54087943397 10089.583969840865 50926.908613734246 13842.267773123085 32003.010392470125 46170.18702661463 16957.770049555114 26923.416804681692 59659.624175653655 17488.3464823414 0.657954763822442 0.5769318431578808 2.9120482411048374 0.7915138110455503 1.829962050716727 2.6400544541609063 0.9696611435894167 1.5395061409531894 3.411393080294588 1.0 14.09410626889491 -5.221092334630958 24.60941779865929 1.859039877777501 0.617441914098141 0.2714200350861963 0.8308668330651487 563.8317657443732 343903.3063256714 0.20321142466658987 0.5376299845147049 6.010459365162652e-06 5.221092334630958 -1.24159796367936 PS(ph)SPPRGPGPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PSSPPRGPGPAR 12 1 J3KNZ9;Q9HAH7 J3KNZ9 FBRS Probable fibrosin-1 1 PS(0.811)S(0.189)PPRGPGPAR 58.268 0.032542 3152900.0 3555.0 4580.9 6689.7 4997.9 7164.9 3979.1 4824.8 5955.9 5356.4 4503.7 True False 4156.791285549453 5035.661477886583 6849.207818828533 4717.883866410421 5760.989278665008 3770.4289911947913 4367.760015472957 5799.563935797675 5434.727216686775 5320.185158730415 0.7813245519713098 0.9465199664382115 1.287400271697122 0.8867894115806066 1.0828550335717608 0.7087025881058902 0.8209789481303051 1.090105656619977 1.0215297126958818 1.0 12.377260741466309 -7.791921403220251 24.999740516771073 1.0418632578857716 0.9406144758513911 0.0872885949531661 0.15536641214271366 623.1988433698696 511106.2348669926 0.08928146439555068 0.0428970650624372 1.6146507430533805e-08 7.791921403220251 -0.10124878203438048 PS(ph)Y(ph)QKMPLFMS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 PSYQKMPLFMSK 12 1 Q9HBJ7 Q9HBJ7 USP29 Ubiquitin carboxyl-terminal hydrolase 29 3 PS(1)Y(1)QKMPLFMS(1)K 52.725 0.041038 0.0 4023.5 2578.8 2762.2 3182.1 3940.1 5737.0 3328.5 2854.5 4054.1 3281.1 True False 3966.124152180465 2572.8289470409986 2535.1025784003436 3416.1222491744165 3708.3510645346455 5491.641883600192 3500.8334435244187 2987.1304908645798 3597.4845664344 3848.2337632090653 1.0306349344206913 0.6685739758427516 0.6587704215469246 0.887711729426149 0.963650155556618 1.427055169075976 0.9097247357980282 0.7762341569327103 0.9348404457203339 1.0 11.90998072378539 -6.08596778619707 3.4594140398270614 1.0063350927373849 0.774157251819347 0.21548825488102308 0.18384241177831778 0.38718900923006105 8.797465268897707 0.05991916599919765 0.08214806013823946 8.204123961808227e-07 6.08596778619707 -0.23217784091803784 PSADLTNSSAPSPS(ph)HK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PSADLTNSSAPSPSHK 16 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 PSADLT(0.011)NS(0.018)S(0.018)APS(0.236)PS(0.717)HK 157.07 8.526799999999998e-15 0.0 8989.2 12145.0 10369.0 11234.0 11400.0 8738.9 12133.0 4869.7 5658.3 8196.6 True False 10510.894015207075 13350.675336491215 10616.23628465148 10604.595401119412 9166.251835584737 8280.616700045774 10983.674404686915 4741.87553487365 5741.041933048087 9682.578695750099 1.0855469751896303 1.3788346840239085 1.0964265427877375 1.095224292447425 0.9466746538923573 0.8552077871239324 1.1343749170360884 0.4897327131412798 0.592924892577218 1.0 13.241175606555474 -6.590980332594355 0.7328876531287931 0.7230480676003671 1.2338800717991047 0.46179585167230197 0.18363791990826983 0.5976175146864615 0.7148926715958309 0.12518549668487597 0.15022259236743765 2.5646001740510544e-07 6.590980332594355 0.5108320041987376 PSADLTNSSAPSPS(ph)HK ddPTM_PC-9_Lapatinib_30min_R1 1 PSADLTNSSAPSPSHK 16 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 PS(0.002)ADLT(0.004)NS(0.036)S(0.036)APS(0.433)PS(0.489)HK 85.469 0.004721100000000001 5077400.0 4946.3 11096.0 12373.0 12990.0 11127.0 13280.0 9608.8 8493.2 10037.0 11130.0 True False 4875.764854959674 11070.307893736208 11355.7397011612 13945.327933369697 10472.531736523695 12712.045357192006 10106.296647780518 8887.825077950974 8906.52736570436 13053.805670207219 0.37351290329743936 0.8480521445942802 0.8699179371942447 1.0682959656123274 0.8022588968384307 0.973819105198171 0.7742030870618966 0.680860838784793 0.682293546473714 1.0 13.672182846967315 -4.7614579700403095 8.591514084605576 0.8524081010089666 0.36924274416694797 0.5815022822953776 0.12265258594769603 0.06614472436006935 55.80474793797037 0.03220698649513468 0.18569831812617738 1.731976639110379e-05 4.7614579700403095 -0.4831653568420186 PSANRENFS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 1 PSANRENFSPER 12 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;H3BSK8 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 PSANRENFS(1)PER 89.507 0.035976 14312000.0 60182.0 28296.0 28778.0 30895.0 22475.0 24138.0 15890.0 17768.0 30444.0 18980.0 True False 59323.793643972895 28230.48235050105 26411.983926292487 33167.121362698745 21153.06468755011 23105.674008426253 16712.706449632875 18593.56614527303 27015.07613046762 22260.667710739715 2.6649602076110224 1.2681776987705171 1.186486599121641 1.4899427902918285 0.9502439442705828 1.0379596114845586 0.7507729178118852 0.8352654281031524 1.2135788773952243 1.0 14.442209246646465 -2.5767402892737468 1.0717188315521986 1.0145052874819644 199.99999999646485 0.8511702450254324 0.19982264825812823 74.32884076881126 0.9255817651934064 0.06524329203445409 35427.869179142835 0.002650084431365547 2.5767402892737468 198.98549470898288 up PSAQEITSLADS(ph)LQLEK ddPTM_PC-9_AZD4547_30min_R2 1 PSAQEITSLADSLQLEK 17 0 P20265-3;P20265-2;P20265 P20265-3 POU3F2 POU domain, class 3, transcription factor 2 1 PSAQEITSLADS(1)LQLEK 67.312 0.010740000000000001 30852000.0 6419.2 4793.3 86903.0 150960.0 94245.0 52517.0 14065.0 113330.0 27085.0 43074.0 True False 8460.372072345453 6342.640486909674 85750.60943858842 116158.50430875033 81160.70853711615 49233.1036879563 15316.757752484613 95817.4525643224 28516.657804876595 41565.99237070523 0.2035407213880964 0.15259206204781542 2.0629992103598496 2.79455626303334 1.952574783089177 1.1844563519348255 0.36849253148782074 2.305188619335175 0.6860574276815412 1.0 15.343116035242577 -5.249764230923177 24.014992414751184 1.5952944253165982 0.17806591734910954 0.36566202336742504 0.7172720713648449 473.6989792284637 974358.0900161733 0.19227296673945404 0.4987247885399605 5.626466910084216e-06 5.249764230923177 -1.4172285079674887 PSDSVSSTPAATS(ph)TPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PSDSVSSTPAATSTPSK 17 0 H0Y5D5;A0A494C0L7;Q9BTG3;Q5SYW2;F5H2X7;Q9ULV3-5;Q9ULV3-3;Q9ULV3-4;Q9ULV3-2;Q9ULV3 H0Y5D5 CIZ1 Cip1-interacting zinc finger protein 1 PSDSVSSTPAAT(0.001)S(0.499)T(0.499)PSK 233.28 3.4239e-37 4724000.0 37952.0 40831.0 33814.0 37091.0 35914.0 27216.0 37113.0 30900.0 27805.0 29173.0 True False 44376.524013832015 44884.431837321754 34620.2540003091 35012.91152064449 28876.909510806174 25788.7450489702 33597.38796514837 30088.90774125629 28211.59552310802 34461.83396665906 1.2877005923934624 1.3024388626776593 1.0045969704863444 1.015990952614959 0.8379388496486821 0.7483277028703739 0.9749158445152102 0.8731081395832426 0.8186330289444843 1.0 15.072711859527873 -5.429479051032684 1.4118747170368013 0.8730475975417814 1.3383879467709672 0.7992276299012353 0.07913161047314655 0.21075635832813433 0.7388552302327175 0.024588172325409583 0.09829359551389322 3.719811639027163e-06 5.429479051032684 0.46534034922918577 PSDSVSSTPAATST(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 2 PSDSVSSTPAATSTPSK 17 0 H0Y5D5;A0A494C0L7;Q9BTG3;Q5SYW2;F5H2X7;Q9ULV3-5;Q9ULV3-3;Q9ULV3-4;Q9ULV3-2;Q9ULV3 H0Y5D5 CIZ1 Cip1-interacting zinc finger protein 1 PSDSVSSTPAAT(0.002)S(0.206)T(0.791)PS(0.001)K;PSDSVSSTPAATS(0.047)T(0.952)PS(0.001)K 149.59 0.00014962 13023000.0 105635.0 94697.0 114087.0 72771.0 85860.0 102133.0 112898.0 119278.0 110475.0 117757.0 True False 139224.73265550446 125305.95334923455 112574.1318368785 55994.77025074239 73939.8210514804 95746.60736451116 122945.70328759395 100846.32583576477 116314.48296081743 113634.36327244136 1.2251992147983397 1.102711800732409 0.9906697991256314 0.49276265240729566 0.650681879337923 0.8425849770016853 1.0819412345614892 0.8874632895507415 1.0235854684374868 1.0 16.794039649297737 -5.341488959759928 3.323644824694733 0.8453531183534303 1.1743908039046813 0.3382029989948352 0.16987394682066512 0.2885197227430112 6.099549161350295 0.05041396539790367 0.1251146757221471 4.5552376593021175e-06 5.341488959759928 0.329037685551251 PSDSVSSTPAATST(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PSDSVSSTPAATSTPSK 17 0 H0Y5D5;A0A494C0L7;Q9BTG3;Q5SYW2;F5H2X7;Q9ULV3-5;Q9ULV3-3;Q9ULV3-4;Q9ULV3-2;Q9ULV3 H0Y5D5 CIZ1 Cip1-interacting zinc finger protein 1 PSDSVSSTPAAT(0.003)S(0.186)T(0.809)PS(0.002)K 125.39 9.431e-05 5502200.0 28092.0 33266.0 28065.0 35781.0 32204.0 27596.0 34060.0 27766.0 25664.0 27771.0 True False 32847.42075770891 36568.42863266502 28734.176037105186 33776.30657356717 25893.857378348315 26148.81718001846 30833.59022695426 27037.171920508797 26039.287448482075 32805.662464884976 1.0012728989353175 1.114698679589467 0.8758907419675525 1.0295877002856189 0.7893106077667225 0.7970824307543867 0.9398862242138347 0.8241617418776181 0.7937436860589053 1.0 15.00165723417755 -5.714170132708721 1.270190686914221 0.8543543057786172 1.0520826641862404 0.3724136806189029 0.08766632061840712 0.48038590132354303 1.5129832892464177 0.029130178362736753 0.0795099941107155 1.9312116262379674e-06 5.714170132708721 0.19772835840762326 PSDSVSSTPAATST(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 2 PSDSVSSTPAATSTPSK 17 0 H0Y5D5;A0A494C0L7;Q9BTG3;Q5SYW2;F5H2X7;Q9ULV3-5;Q9ULV3-3;Q9ULV3-4;Q9ULV3-2;Q9ULV3 H0Y5D5 CIZ1 Cip1-interacting zinc finger protein 1 PSDSVSSTPAATS(0.042)T(0.951)PS(0.006)K;PSDSVSSTPAAT(0.012)S(0.157)T(0.831)PSK 279.19 1.4127e-82 17199800.0 54174.0 115193.0 101845.0 116260.0 118077.0 106963.0 112358.0 108704.0 93159.0 113435.0 True False 53401.468825705095 114926.27768593682 93471.69723306898 124810.14823199104 111131.94300831386 102388.44183293135 118175.34746808387 113754.78468346244 82666.4524122399 133042.0886073638 0.4013877817515663 0.8638339858381907 0.7025723830067364 0.9381252920670314 0.8353141789309129 0.7695943659987325 0.8882553536636445 0.855028554303425 0.6213556422449636 1.0 17.021523197000803 -4.758274765050633 24.985071397054117 0.8253478106860559 0.4013871949776175 0.6018899212850047 0.10461168865579773 58.24863880263088 459803.07768776274 0.024424802185388245 0.16953968501977365 1.744717973104232e-05 4.758274765050633 -0.4239606157084384 PSGGFVISGVLS(ph)PDTISSK ddPTM_PC-9_AZD4547_30min_R2 1 PSGGFVISGVLSPDTISSK 19 0 H0Y8J2;Q03188;H0Y9W1 H0Y8J2 CENPC Centromere protein C 1 PSGGFVIS(0.006)GVLS(0.957)PDT(0.036)ISSK 216.35 8.866e-28 5556900.0 48867.0 50106.0 54791.0 64008.0 54774.0 51811.0 45637.0 54470.0 53562.0 64652.0 True False 64405.68950325669 66301.78462376576 54064.43554019655 49251.94451374201 47169.57556806184 48571.24997956288 49698.6045894163 46052.91309607896 56393.17797100975 62388.55315853726 1.032331834007973 1.062723548906231 0.8665762035354777 0.7894387995917544 0.7560613795322026 0.7785282318719132 0.7965981269532861 0.7381628642525601 0.9039026410455056 1.0 15.928993732093485 -5.365151718482517 3.442290800651079 0.8074203983046111 1.049968247376769 0.5750111288615741 0.07492845356109275 0.14440383666287057 3.155081400957034 0.018995529118878595 0.045338430730608566 4.31368354246948e-06 5.365151718482517 0.24254784907215798 PSGGFVISGVLS(ph)PDTISSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PSGGFVISGVLSPDTISSK 19 0 H0Y8J2;Q03188;H0Y9W1 H0Y8J2 CENPC Centromere protein C 1 PSGGFVIS(0.018)GVLS(0.981)PDT(0.001)ISSK;PSGGFVISGVLS(0.998)PDT(0.002)ISSK 179.1 6.5909e-09 7844800.0 74554.0 68434.0 60668.0 83119.0 88481.0 66950.0 81223.0 80076.0 69467.0 66308.0 True False 87174.5196913795 75227.67525544975 62114.55520467122 78462.11190543383 71143.78321617322 63439.024141260845 73528.96943640376 77974.0898475351 70482.82345634748 78329.11550616074 1.1129261338910823 0.960405013759321 0.7929944670418981 1.0016979177974075 0.9082674144402616 0.8099034915857213 0.9387182398430193 0.9954675134995272 0.899829175918677 1.0 16.257261047073918 -4.80586821198687 4.035735055527629 0.9155125616527336 1.1252617616019545 0.4108872023777628 0.06946961961352283 0.20419840515758528 6.081654829079836 0.01725942829946621 0.11727787926775392 1.5636220566390494e-05 4.80586821198687 0.2097491999492208 PSGGFVISGVLS(ph)PDTISSK ddPTM_PC-9_Lapatinib_30min_R1 2 PSGGFVISGVLSPDTISSK 19 0 H0Y8J2;Q03188;H0Y9W1 H0Y8J2 CENPC Centromere protein C 1 PSGGFVISGVLS(0.962)PDT(0.038)ISSK;PSGGFVISGVLS(0.513)PDT(0.475)IS(0.009)S(0.003)K 192.22 8.2321e-12 8225900.0 78797.0 81403.0 72636.0 68286.0 65835.0 68837.0 59711.0 63098.0 59935.0 56677.0 True False 77673.34033039978 81214.51635488549 66664.14846306818 73307.9802354182 61962.71473659 65893.00197688451 62802.54341183316 66029.76343057404 53184.489156470154 66473.54393264471 1.168485020282707 1.2217569810506461 1.0028673742837693 1.1028143814582623 0.932140985282425 0.9912665713092047 0.9447750141841205 0.993323953022268 0.8000850565506198 1.0 16.020492650516793 -5.428215800567211 0.6486303195943979 0.9300899689082457 1.2714996359826003 0.6418717795323843 0.06911966942797886 1.0139880624712654 0.5568681729099494 0.03454639036712037 0.229281710652336 3.7306473617417773e-06 5.428215800567211 0.3414096670743546 PSGGFVISGVLSPDT(ph)ISSK ddPTM_PC-9_AZD4547_30min_R2 1 PSGGFVISGVLSPDTISSK 19 0 H0Y8J2;Q03188;H0Y9W1 H0Y8J2 CENPC Centromere protein C 1 PSGGFVISGVLS(0.417)PDT(0.477)IS(0.104)S(0.002)K 161.35 1.1169000000000001e-05 6204100.0 19008.0 21066.0 24927.0 28567.0 23073.0 20865.0 20774.0 20132.0 16272.0 25152.0 True False 25052.148609038897 27875.172531917313 24596.451692987546 21981.31950575033 19869.712218970515 19560.308251598664 22622.845755429476 17021.06198733729 17132.104700053602 24271.436135672968 1.0321658952936237 1.1484764385634252 1.0133908663458477 0.9056456067485542 0.8186459222232418 0.8058982642090091 0.9320769331065468 0.7012795572619852 0.7058545940293032 1.0 14.566971854520371 -5.80547706957045 1.9085267436440931 0.8159980641215618 1.0924321958270367 0.5867759621563732 0.08985308649032954 0.2224319547098924 1.6546630459000489 0.027904052787734668 0.05373764249228842 1.5650309495276833e-06 5.80547706957045 0.2764341317054748 PSHYPVS(ph)S(ph)VY(ph)T(ph)ET(ph)LK ddPTM_PC-9_AZD4547_30min_R2 1 PSHYPVSSVYTETLK 15 0 Q59H18-4 Q59H18-4 5 PS(0.034)HY(0.077)PVS(0.914)S(0.989)VY(0.995)T(0.992)ET(0.999)LK 49.148999999999994 0.028813 6617900.0 8452.4 6211.4 9745.5 11150.0 14629.0 7829.9 8887.2 14663.0 10131.0 12664.0 True False 11140.087379158262 8219.11357945273 9616.268302403414 8579.539765782767 12598.015864920895 7340.295115226091 9678.143583212326 12397.170272219682 10666.50397715358 12220.637214621596 0.911579910565507 0.6725601484690854 0.7868876338868698 0.7020533884695984 1.0308804396752551 0.6006474937692828 0.7919508134676267 1.0144454871294986 0.8728271521219412 1.0 13.577031892398946 -7.7297184461281025 11.33794304375082 0.9576835482797077 0.7800315806330307 0.31560456950816806 0.1193485409517603 0.7134245962393116 252.80739293188518 0.05417789561891534 0.03105703448388437 1.863294722406743e-08 7.7297184461281025 -0.177651967646677 PSMS(ph)PTPLDR ddPTM_PC-9_AZD4547_30min_R2 4 PSMSPTPLDR 10 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 PS(0.107)MS(0.774)PT(0.119)PLDR;PS(0.229)MS(0.613)PT(0.158)PLDR;PS(0.023)MS(0.819)PT(0.158)PLDR;PS(0.004)MS(0.982)PT(0.014)PLDR 103.08 0.0029671999999999997 168951300.0 430713.0 414178.0 419759.0 346526.0 356025.0 433987.0 413268.0 442298.0 387213.0 386251.0 True False 567670.7746130566 548052.9388077682 414192.7213943416 266639.7844733309 306597.07418883406 406849.7242840428 450048.0513938012 373951.0070969247 407680.28866899316 372728.47005565464 1.5230142589544977 1.4703812100157914 1.1112451950142035 0.7153727334901921 0.8225748737225625 1.091544534345051 1.2074421128243877 1.0032799668914143 1.0937728706586851 1.0 18.507765494843547 -5.308271632141167 3.693551147576379 0.9925236318922787 1.5094116178362762 0.6934636024071926 0.1324169805889607 0.1339104096821017 3.7857520944720187 0.03977252564436937 0.09840887116936431 4.917318827647833e-06 5.308271632141167 0.5168879859439975 PSMS(ph)PTPLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PSMSPTPLDR 10 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 PS(0.084)MS(0.815)PT(0.102)PLDR 96.229 0.0049413 86277000.0 293530.0 397080.0 262530.0 262220.0 274120.0 181860.0 266510.0 189670.0 209530.0 195320.0 True False 343218.8315182363 436499.4781897011 268789.71085056907 247528.66352870993 220408.153786885 172322.94145376707 241264.2434346913 184691.36347197622 212593.9798581843 230729.969847731 1.4875346785020678 1.8918195953380768 1.1649536080118044 1.0728067259405665 0.9552645195261897 0.7468598100519437 1.0456562864109606 0.8004654254228971 0.9213973373224317 1.0 17.815845884363625 -5.491748165472509 2.552608285528581 0.9202266821824004 1.692062364680494 0.8202882762438564 0.13812362481936188 0.10171688915632668 1.303608986978627 0.03711505233336778 0.08791712322817134 3.22293713547138e-06 5.491748165472509 0.7718356824980935 PSMS(ph)PTPLDR ddPTM_PC-9_Lapatinib_30min_R1 5 PSMSPTPLDR 10 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 PS(0.014)MS(0.778)PT(0.208)PLDR;PS(0.093)MS(0.749)PT(0.158)PLDR;PS(0.005)MS(0.555)PT(0.44)PLDR;PS(0.001)MS(0.862)PT(0.137)PLDR;PSMS(0.986)PT(0.014)PLDR 136.81 0.00011382 154130000.0 220065.0 409503.0 359962.0 360922.0 437459.0 357324.0 403877.0 433857.0 354964.0 416709.0 True False 216926.8327450212 408554.82096329005 330367.31385350233 387465.4078804961 411728.5216974847 342042.08548292756 424787.7748746615 454015.5800928479 314984.21638336976 488736.5954201602 0.4438522402001269 0.83594071897166 0.675961892253004 0.7927898412178391 0.8424344024075531 0.6998495481781524 0.8691548348440682 0.9289576110062657 0.6444866607800918 1.0 18.89869760859888 -4.758182479600648 24.993983000087514 0.8024335970400339 0.44385174291217055 0.5135610594671742 0.10666497200185801 73.24984263226091 562038.6239227509 0.025040965559217702 0.17491849563925987 1.7450887565203378e-05 4.758182479600648 -0.35858185412786336 PSMSPT(ph)PLDR ddPTM_PC-9_AZD4547_30min_R2 2 PSMSPTPLDR 10 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 PSMS(0.251)PT(0.749)PLDR;PSMS(0.268)PT(0.732)PLDR 145.46 0.00031548 27646000.0 88472.0 78975.0 82509.0 76750.0 85185.0 93180.0 77487.0 94746.0 88137.0 83298.0 True False 116604.25566808114 104502.1243097013 81414.87674957716 59056.4732756796 73358.53315013241 87353.43986982835 84383.19288779073 80105.18274648627 92795.7418847483 80381.76237393783 1.4506307428995575 1.3000725689933867 1.0128525967225408 0.734699906191998 0.9126265832399494 1.0867320806361287 1.0497803282197042 0.9965591743788236 1.154437762300612 1.0 16.294580588449804 -5.157526153019724 3.119110840540563 0.9851642410220749 1.424903946539211 0.6822480893154899 0.10641498499125306 0.158385553412803 2.864531560024542 0.03089763427100405 0.10676512765693164 6.95783053694264e-06 5.157526153019724 0.43973970551713615 PSMSPT(ph)PLDR ddPTM_PC-9_Lapatinib_30min_R1 1 PSMSPTPLDR 10 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 PSMS(0.266)PT(0.734)PLDR 131.12 0.00046576 27252000.0 37848.0 79759.0 67595.0 68034.0 86206.0 78600.0 72562.0 86043.0 63636.0 76764.0 True False 37308.28057952686 79574.32293587853 62037.60002424555 73037.44731477102 81135.53256751703 75238.46122554908 76318.90531140717 90040.8718954145 56468.643563212376 90032.55511839956 0.414386557512043 0.8838394382035736 0.6890574186488594 0.811233750044318 0.9011799394209986 0.8356806171568147 0.8476812105470304 1.0000923752192084 0.6272024990177373 1.0 16.458159143384698 -4.7578139679072695 24.906876659399458 0.8397758616459671 0.4143859248658782 0.5686445234339124 0.1121974396595955 70.60946195884556 485016.6264112561 0.02633231597496083 0.1893020443746978 1.746570144277546e-05 4.7578139679072695 -0.42538993678008885 PSPGTPT(ph)SPSNLTSGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 PSPGTPTSPSNLTSGLK 17 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 PSPGT(0.003)PT(0.457)S(0.3)PS(0.006)NLT(0.199)S(0.035)GLK;PSPGT(0.001)PT(0.595)S(0.38)PS(0.013)NLT(0.009)S(0.002)GLK;PSPGTPT(0.494)S(0.494)PS(0.004)NLT(0.006)S(0.001)GLK 115.92 0.00035886 7913800.0 94613.0 156958.0 109821.0 107040.0 109072.0 76861.0 106126.0 74924.0 75516.0 80124.0 True False 110629.11220807018 172539.75294071523 112439.54913846192 101042.8958283623 87700.1245799033 72830.27385394248 96072.97699429693 72957.32438853983 76620.27863776391 94649.846938765 1.1688250513457585 1.822926909246268 1.1879527836025578 1.0675442073745072 0.9265743941101362 0.7694705930275937 1.0150357354138422 0.7708129146340887 0.8095129692849312 1.0 16.530312552452934 -5.7160185123799305 2.001245328124809 0.8773215428735361 1.4971041548646267 0.6410120415482115 0.17613122084073715 0.18031371477249736 1.468290598737705 0.050236432777184904 0.10391179052312736 1.9230097563144867e-06 5.7160185123799305 0.6197826119910905 PSPGTPT(ph)SPSNLTSGLK ddPTM_PC-9_Lapatinib_30min_R1 1 PSPGTPTSPSNLTSGLK 17 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 PSPGTPT(0.998)S(0.002)PSNLTSGLK 216.01 5.8273e-22 4496000.0 14117.0 24699.0 20431.0 23510.0 26570.0 23591.0 26897.0 32685.0 20924.0 26971.0 True False 13915.688991259269 24641.810983002026 18751.242045940697 25239.003827060933 25007.204838629852 22582.06792330697 28289.595051968237 34203.664422458845 18567.31878051191 31632.901413401516 0.4399118755943071 0.778993069935796 0.5927765461942922 0.797871921301795 0.7905441398440727 0.7138791231379082 0.8943092093342768 1.0812686441708508 0.5869622434521837 1.0 14.949138267455147 -3.9053546393125376 0.27952477743899246 0.931226679808105 6.689247001394565e-15 0.40626816425452816 0.1428067054916699 14.60489678005932 0.6422000409060736 0.1645293046669253 5.073798613578606 0.0001243498771893487 3.9053546393125376 -0.9312266798080984 PSPGTPTS(ph)PSNLTSGLK ddPTM_PC-9_AZD4547_30min_R2 1 PSPGTPTSPSNLTSGLK 17 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 PSPGTPT(0.016)S(0.962)PS(0.005)NLT(0.013)S(0.004)GLK 135.61 4.2006000000000004e-05 6953300.0 46677.0 54637.0 49920.0 42768.0 41989.0 47714.0 47267.0 60451.0 54706.0 51395.0 True False 61519.31505808648 72297.34176523157 49258.02818285143 32908.49835901321 36159.55213289788 44730.43603722881 51473.67143168792 51109.686975786106 57597.647475487465 49595.676693420486 1.2404168903344719 1.4577347580544808 0.9931919769407269 0.6635356255433239 0.7290867781968365 0.9019019200752811 1.037866097681788 1.0305270616978288 1.161344119398386 1.0 15.597926744419528 -5.351255028371344 5.490196248167701 0.921884504190981 1.3466011449737578 0.5514622649690345 0.1478483763113231 0.16167742036628513 7.610823627496302 0.04329698748745693 0.09288121984333572 4.453946249415869e-06 5.351255028371344 0.4247166407827768 PSPGTPTSPS(ph)NLTSGLK ddPTM_PC-9_Lapatinib_30min_R1 1 PSPGTPTSPSNLTSGLK 17 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 PSPGTPT(0.015)S(0.075)PS(0.582)NLT(0.275)S(0.053)GLK 138.24 6.7622e-05 4422000.0 10033.0 24848.0 19014.0 22353.0 20972.0 26068.0 28396.0 26576.0 23339.0 31420.0 True False 9889.927580173142 24790.465982656577 17450.742316162516 23996.91418742207 19738.468192538414 24953.132407475998 29866.2059373049 27810.817980457912 20710.316049434514 36850.90513548166 0.26837678867894854 0.672723394215553 0.4735498965901974 0.6511892747056786 0.535630485057838 0.677137571403912 0.8104605796656108 0.7546848002297898 0.5620029134506581 1.0 15.169412434919552 -6.655943756614154 0.1067658877323913 1.2499083025905424 2.3887148189188733e-15 0.5976390798483364 0.11987917538710637 15.750951305414599 0.6555352907466873 2.60480456263076 4.775010408519693 2.2082906995900036e-07 6.655943756614154 -1.24990830259054 PSPPHTSPAHQGGSYRFSPPPVGGQGK ddPTM_PC-9_Lapatinib_30min_R1 1 PSPPHTSPAHQGGSYRFSPPPVGGQGK 27 1 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 0 51.827 0.016931 2940100.0 642.06 460.85 13333.0 2369.2 5043.6 7708.8 3359.8 2703.5 15115.0 2933.8 False True 632.9041066606163 459.7829301395394 12236.812206868362 2543.438871419513 4746.945364099117 7379.112594090491 3533.7540043723416 2829.1144796119775 13412.589531993764 3440.903420957228 0.18393544637313541 0.13362273620909476 3.5562788924381357 0.7391776403628183 1.3795636736524735 2.1445276694333053 1.026984361970056 0.8222010714921326 3.897984886847683 1.0 11.748571683839145 -5.11803700388857 20.430075892706547 1.7501931670367632 0.1569213108360677 0.28222667286477265 1.0553937906168405 5.563612200591681 937.2344116153103 0.25618831374756945 0.6778188566079044 7.620140801527166e-06 5.11803700388857 -1.5932718562006956 PSPSTTPLPDS(ph)SPSR ddPTM_PC-9_Lapatinib_30min_R1 1 PSPSTTPLPDSSPSR 15 0 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 PSPSTTPLPDS(0.488)S(0.488)PS(0.024)R 69.878 0.024857 2790700.0 4675.2 13238.0 15667.0 10048.0 10950.0 11377.0 9498.8 11854.0 13149.0 10165.0 True False 4608.530790673323 13207.348224340292 14378.919736368896 10786.9634391454 10305.942528528309 10890.432231082339 9990.601386014652 12404.78011515458 11668.021154891561 11922.006705988895 0.386556634661032 1.107812514289706 1.2060821714808965 0.904794277101579 0.8644469662436296 0.9134730838233504 0.8379966252657767 1.0404943078016529 0.9786960737935378 1.0 13.541339469470088 -4.753762348032413 24.994049861559223 0.9790211149672637 0.38655557183502137 0.7357935589488656 0.10732405958571996 158.92979814762117 517384.17196093185 0.02951103391267049 0.30744758139689515 1.7629404880105778e-05 4.753762348032413 -0.5924655431322423 PSPVDSNRST(ph)PSNHDRIQR ddPTM_PC-9_Lapatinib_30min_R1 1 PSPVDSNRSTPSNHDRIQR 19 2 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-5 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 PSPVDS(0.034)NRS(0.012)T(0.477)PS(0.477)NHDRIQR 87.419 0.015401 0.0 0.0 2393.3 1164.4 2133.8 2069.6 1006.8 1067.7 787.33 2614.6 2400.7 True False 0.0 2387.7584608939146 1068.6675267139815 2290.7267701481333 1947.870196990153 963.7415109654296 1122.9802817037776 823.9122260894757 2320.11621504141 2815.657796268324 0.0 0.8480286432742227 0.37954453418676043 0.8135671789320784 0.6917993371111092 0.3422793466744095 0.3988340782008727 0.2926180259481217 0.8240050400003616 1.0 11.459256289934762 -8.465865406549307 5.132224518647688 0.998404027378226 0.4937130156251661 0.35024824665390275 0.24435437270948615 0.20364063590576606 10.851156841202013 0.2286857552679087 0.059470902469158766 3.4208544276988037e-09 8.465865406549307 -0.5046910117530599 PSQCSEFIQQSSMKS(ph)PLYLVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PSQCSEFIQQSSMKSPLYLVSR 22 1 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 PSQCS(0.07)EFIQQS(0.036)S(0.354)MKS(0.509)PLY(0.031)LVSR;PSQCS(0.001)EFIQQS(0.19)S(0.19)MKS(0.608)PLY(0.011)LVSR 60.332 0.011492 17934500.0 61856.0 55974.0 45494.0 66686.0 71990.0 49652.0 65892.0 49880.0 57526.0 47484.0 True False 72326.99908831126 61530.728800721234 46578.749496955796 62949.799618929086 57884.07628453898 47048.16171264949 59650.232743231696 48570.702852228584 58367.20892150014 56092.47331686285 1.2894243168729715 1.0969516079838024 0.830392149653223 1.1222503822095637 1.0319401670444353 0.8387606915972021 1.0634266812638353 0.8659041040650096 1.0405533125948547 1.0 15.775519577532656 -4.8991660502986685 3.5749791576120225 0.9741788296096794 1.2922275454078462 0.5097134226570191 0.09506288722196403 0.19118267511392634 4.272643514586326 0.023029915117960403 0.13482894022148775 1.2613451734346877e-05 4.8991660502986685 0.31804871579816685 PSQCSEFIQQSSMKS(ph)PLYLVSR ddPTM_PC-9_Lapatinib_30min_R1 1 PSQCSEFIQQSSMKSPLYLVSR 22 1 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 PSQCS(0.002)EFIQQS(0.154)S(0.154)MKS(0.689)PLY(0.001)LVSR 71.794 0.00070637 7096700.0 10666.0 18753.0 18022.0 14043.0 13375.0 12414.0 15065.0 16644.0 15109.0 12293.0 True False 10513.90088409516 18709.578580680878 16540.300726931797 15075.76906607471 12588.308796261734 11883.082158447412 15844.99198638888 17417.34100190929 13407.265315176568 14417.828670607127 0.7292291456846965 1.2976696427821421 1.1472116297686101 1.0456338059286896 0.8731071150765483 0.8241936029294641 1.0989860088080556 1.2080418903449113 0.9299087693079097 1.0 13.815566290174086 -6.005389196053527 24.150467928288382 0.9933033921293621 1.0844038737727901 0.028935154354872372 0.16732202981394162 523.9719110897005 2348102.795843509 0.04886533319227611 0.07006051746627356 9.876675926842138e-07 6.005389196053527 0.09110048164342799 PSQGLPVIQS(ph)PPS(ph)SPPHR ddPTM_PC-9_AZD4547_30min_R2 1 PSQGLPVIQSPPSSPPHR 18 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 2 PSQGLPVIQS(0.993)PPS(0.58)S(0.427)PPHR 108.97 0.0062608 0.0 7369.0 7384.4 9890.7 10817.0 10964.0 10136.0 9798.2 14766.0 11142.0 10017.0 True False 9712.188715278171 9771.26289018751 9759.54285553143 8323.307770984049 9441.837852415925 9502.19431767094 10670.220818371477 12484.253988924218 11730.943373156178 9666.30787893751 1.0047464695843833 1.0108578179553636 1.0096453555754286 0.8610637975974463 0.9767781008702716 0.98302210489031 1.1038569174505037 1.291522486690797 1.2135909097947755 1.0 13.238749231046038 -7.399855075637897 3.3311281942178295 1.1907930309931218 0.972084579591396 0.5427124310441767 0.08031123240768283 0.17206964526086907 3.5515776200927065 0.03672498837089664 0.023110806562411736 3.9824004135365236e-08 7.399855075637897 -0.2187084514017258 PSS(ph)PGGLPEEDSVLFNK ddPTM_PC-9_AZD4547_30min_R2 1 PSSPGGLPEEDSVLFNK 17 0 A0A0U1RQY6;A0A0C4DG54;Q5R372-2;Q5R372-4;Q5R372;Q5R372-3 A0A0U1RQY6 RABGAP1L Rab GTPase-activating protein 1-like 1 PS(0.007)S(0.993)PGGLPEEDSVLFNK 163.9 5.4314e-18 0.0 9570.6 10101.0 7322.5 6135.5 9348.1 10225.0 11815.0 12017.0 10286.0 8348.4 True False 12613.851719153381 13365.950714179087 7225.3988655634985 4721.055267530059 8050.277674951606 9585.62913360155 12866.512111312179 10160.048773188559 10829.696960714813 8056.12505705519 1.5657467616030538 1.6591041747140942 0.8968826593916663 0.5860206034656291 0.9992741693975489 1.189856049367914 1.5971092827120736 1.2611582741371234 1.344281138142295 1.0 12.975870363462718 -7.013848584363119 23.590384778220802 1.3325549845700015 1.1226111079936711 0.04739368013759859 0.3200164852060135 941.3159216795492 1603484.5458980643 0.132771516937246 0.10744975576041146 9.686155026633586e-08 7.013848584363119 -0.2099438765763304 PSSIPAPAEAEAWS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 PSSIPAPAEAEAWSPR 16 0 D3YTB5;P51617-4;P51617-2;P51617-3;P51617;H7C1F0;F8WAB6 D3YTB5 IRAK1 Interleukin-1 receptor-associated kinase 1 1 PSSIPAPAEAEAWS(1)PR;PSSIPAPAEAEAWS(1)PR 247.5 4.3279999999999997e-47 12783300.0 38629.0 43007.0 40720.0 38409.0 38392.0 42758.0 43919.0 52185.0 39345.0 43736.0 True False 50912.21846688571 56908.17170227705 40180.026194024635 29554.398463134552 33061.933494158366 40084.33550068805 47827.70591762334 44121.007342002566 41424.696375590516 42204.81595220233 1.2063130076090052 1.3483809944042056 0.952024675087535 0.7002612805279239 0.7833687399940701 0.9497573818609764 1.133228633713011 1.0454021975115437 0.9815158635570095 1.0 15.365120012461349 -5.270941539006018 23.52856053538206 0.9374533434785655 1.2773470009065795 0.5494278206293268 0.12095124108522712 218.08127812028073 540000.0536263732 0.03632730963906144 0.07744377604033247 5.358687867132296e-06 5.270941539006018 0.33989365742801403 PSSIPAPAEAEAWS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PSSIPAPAEAEAWSPR 16 0 D3YTB5;P51617-4;P51617-2;P51617-3;P51617;H7C1F0;F8WAB6 D3YTB5 IRAK1 Interleukin-1 receptor-associated kinase 1 1 PSSIPAPAEAEAWS(1)PR;PSSIPAPAEAEAWS(1)PR 176.49 9.8456e-06 8288300.0 18230.1 21080.9 20375.9 21607.2 21805.0 20544.8 26094.0 19869.4 22685.0 20091.7 True False 21316.09586911253 23173.67243318548 20861.738732031077 20396.61863548757 17532.4667785022 19467.394520946626 23622.187415799912 19347.849303369505 23016.725209196396 23734.16616419031 0.8981185907964983 0.9763845198045974 0.8789750011739154 0.8593779319815175 0.7387016108851078 0.8202266043927293 0.9952819598710256 0.8151897635469157 0.9697718070215429 1.0 14.534677745014335 -10.231010791711265 7.7902778957483365 0.9999948077315162 0.8805947282386252 0.17022673214058848 0.0768745958873235 0.0 0.0 0.07700608812823591 0.01867671971578464 5.87474754286056e-11 10.231010791711265 -0.119400079492891 PSSIPAPAEAEAWS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 PSSIPAPAEAEAWSPR 16 0 D3YTB5;P51617-4;P51617-2;P51617-3;P51617;H7C1F0;F8WAB6 D3YTB5 IRAK1 Interleukin-1 receptor-associated kinase 1 1 PSSIPAPAEAEAWS(1)PR;PSSIPAPAEAEAWS(1)PR 220.64 1.6023e-22 10485500.0 15170.7 32589.0 29851.0 29139.0 32653.0 32128.0 35539.0 37023.0 40583.0 40414.0 True False 14954.363036034358 32513.5421727622 27396.76600819225 31281.979264854468 30732.414738268013 30753.960334025956 37379.03552633747 38743.223739106434 36012.11518206438 47399.50605172996 0.3154961787937991 0.6859468564351324 0.5779968672730998 0.6599642458449788 0.6483699366978184 0.6488244898683605 0.7885954652258077 0.8173761071860876 0.7597571827597143 1.0 15.53258440448664 -5.244718544960447 0.13864239665780373 1.113628790281531 1.6557150461448897e-15 0.7660521682860767 0.0815195170938816 12.142019946142296 0.33834024931423734 0.5505562420669475 2.639122039421759 5.69221709224607e-06 5.244718544960447 -1.1136287902815294 down PSSS(ph)PVIFAGGQDR ddPTM_PC-9_Lapatinib_30min_R1 1 PSSSPVIFAGGQDR 14 0 Q15366-2;Q15366;Q15366-6;Q15366-3;H3BSS4 Q15366-2 PCBP2 Poly(rC)-binding protein 2 1 PS(0.001)S(0.154)S(0.844)PVIFAGGQDR 89.911 0.0051383999999999996 4812300.0 12024.0 20419.0 20087.0 13753.0 19748.0 17086.0 19153.0 16595.0 17281.0 17031.0 True False 11852.53555506845 20371.721060039632 18435.52439806231 14764.441498663073 18586.461466061817 16355.271609411337 20144.64862365125 17366.064283025997 15334.631803002603 19974.785657618962 0.5933748555918822 1.0198718228683104 0.9229397858910424 0.7391539389576122 0.9304961657484621 0.8187958504161952 1.0085038692751878 0.8693992807077795 0.7676994419789196 1.0 14.285892401734026 PSSTTPTPLVSETGGNS(ph)PSDKVDNELK ddPTM_PC-9_Lapatinib_30min_R1 1 PSSTTPTPLVSETGGNSPSDKVDNELK 27 1 A0A3B3IRW6;Q2KHR3-2;Q2KHR3;H0YCQ7 A0A3B3IRW6 QSER1 Glutamine and serine-rich protein 1 1 PSSTTPTPLVS(0.017)ET(0.014)GGNS(0.744)PS(0.225)DKVDNELK 101.33 6.6735e-10 7480100.0 22350.0 57246.0 40475.0 49175.0 62376.0 49055.0 70080.0 72723.0 47743.0 64721.0 True False 22031.28490151196 57113.45040418377 37147.3017380182 52791.49354299114 58707.166315934344 46957.03200279017 73708.39949592647 76101.97606836389 42365.68058392182 75907.93861468822 0.2902369014833041 0.7524041812555861 0.4893730802858369 0.6954673583083703 0.7733995598791624 0.6186050215530944 0.9710235957015418 1.0025562208277137 0.5581192343922253 1.0 16.211963153215642 -4.572603976468179 0.2974618895981319 0.9260223728634059 4.4160100213111516e-13 0.46106509395793993 0.16413615186320688 8.59261736473753 0.5666738451288575 0.18414560832606455 2.969162392883375 2.6754449757514473e-05 4.572603976468179 -0.9260223728629643 PSSTTPTPLVSETGGNSPS(ph)DKVDNELK ddPTM_PC-9_Lapatinib_30min_R1 1 PSSTTPTPLVSETGGNSPSDKVDNELK 27 1 A0A3B3IRW6;Q2KHR3-2;Q2KHR3;H0YCQ7 A0A3B3IRW6 QSER1 Glutamine and serine-rich protein 1 1 PSSTTPTPLVSETGGNS(0.024)PS(0.976)DKVDNELK 148.66 5.0934e-10 6632600.0 14685.0 42991.0 27685.0 45214.0 44260.0 36341.0 46006.0 52706.0 35514.0 39197.0 True False 14475.589207100811 42891.45698085915 25408.846167190477 48539.18838948247 41656.71381850802 34786.78014500864 48387.96557091317 55154.913172712746 31514.039341000767 45972.14922328051 0.31487736491924345 0.9329878568987746 0.5527008546801488 1.0558390070852288 0.906129352712813 0.7566924917095773 1.0525495629081723 1.19974623994264 0.685502850605077 1.0 15.488472494068063 -4.553637090490885 0.8425966170460825 0.9511946132394752 2.8866415367316705e-21 0.4268337068293099 0.19280667188339223 3.4062925015319307 1.443944549655362 0.06762763838902834 3.2967440545618034 2.7948783499763753e-05 4.553637090490885 -0.9511946132394752 PSTQPRPDS(ph)WGEDNWEGLETDSR ddPTM_PC-9_AZD4547_30min_R2 1 PSTQPRPDSWGEDNWEGLETDSR 23 1 H0YDH0;E9PPN3;E9PS17;Q96KG9-3;Q96KG9-2;Q96KG9 H0YDH0 SCYL1 N-terminal kinase-like protein 1 PST(0.002)QPRPDS(0.998)WGEDNWEGLETDSR 111.35 3.3558e-07 16635000.0 18067.0 22578.0 20669.0 21073.0 19119.0 19589.0 21293.0 19375.0 19137.0 21999.0 True False 23811.930183054785 29875.896963145795 20394.915555115313 16214.945424604495 16464.656867962447 18364.096733312563 23188.03574999325 16381.038943207828 20148.542751040175 21228.82170597446 1.1216793147004176 1.4073271412297828 0.9607182083674263 0.7638174953460134 0.7755803452496269 0.8650549233330423 1.0922902868164088 0.7716414584893182 0.9491126276391374 1.0 14.373736677023404 -5.4009426348019725 5.37552999529394 0.880325465905735 1.2603223399876395 0.6059410866262588 0.11932095262286962 0.13471140720555533 5.308310294382399 0.031047983639861432 0.06615015514043725 3.972440172711727e-06 5.4009426348019725 0.3799968740819045 PSTQPRPDS(ph)WGEDNWEGLETDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 PSTQPRPDSWGEDNWEGLETDSR 23 1 H0YDH0;E9PPN3;E9PS17;Q96KG9-3;Q96KG9-2;Q96KG9 H0YDH0 SCYL1 N-terminal kinase-like protein 1 PS(0.006)T(0.005)QPRPDS(0.989)WGEDNWEGLETDSR;PS(0.001)T(0.011)QPRPDS(0.988)WGEDNWEGLETDSR;PS(0.002)T(0.002)QPRPDS(0.996)WGEDNWEGLETDSR 88.62700000000001 1.1754000000000001e-05 16576200.0 10748.8 14649.7 11449.6 13297.2 13352.1 13207.9 15829.800000000001 16183.5 15699.5 17058.1 True False 12568.359541522912 16104.025399505577 11722.601886849807 12552.200994104052 10735.85185385184 12515.254472820896 14330.286746172655 15758.700272835631 15929.07548696402 20150.598498154686 0.6237214017575644 0.7991834783954591 0.5817495638118797 0.6229195125521226 0.5327807933265599 0.6210859927543588 0.7111593607249416 0.7820462639994912 0.7905013584793893 1.0 14.298535068798813 -8.398628481857774 0.8873900836792759 0.9920155314611567 0.6325585851409293 0.7283063790792963 0.06883404451623987 0.31965754905661176 0.5561176880196738 0.07001180524658074 0.02499916763711883 3.993663951117375e-09 8.398628481857774 -0.3594569463202274 PSTQPRPDS(ph)WGEDNWEGLETDSR ddPTM_PC-9_Lapatinib_30min_R1 2 PSTQPRPDSWGEDNWEGLETDSR 23 1 H0YDH0;E9PPN3;E9PS17;Q96KG9-3;Q96KG9-2;Q96KG9 H0YDH0 SCYL1 N-terminal kinase-like protein 1 PS(0.02)T(0.02)QPRPDS(0.949)WGEDNWEGLET(0.008)DS(0.002)R;PSTQPRPDS(1)WGEDNWEGLETDSR 98.376 3.4084e-06 26587000.0 13633.8 25085.0 19994.4 16410.4 22364.0 26596.0 23395.0 28015.0 18251.7 23101.0 True False 13439.379511867284 25026.91722371782 18350.53761261598 17617.275559489604 21048.593489315692 25458.55107830409 24606.27862738586 29316.679173785687 16196.001347078445 27093.977069852383 0.496028304638279 0.9237077731037652 0.6772921363779673 0.6502284811886271 0.776873525619706 0.9396387622484542 0.9081826032386142 1.0820367603546295 0.5977712797690312 1.0 14.725684558907764 -6.601879552906738 4.057170139271216 0.9102038119056653 0.7035809695229431 0.3130259364304262 0.1521775709668199 0.28188533662641835 8.980151164940795 0.049381903295413136 0.04973060361033882 2.501038902851332e-07 6.601879552906738 -0.20662284238272222 PSVPSADSETPLTQDRPGS(ph)PSGSEDKGNPAPELR ddPTM_PC-9_AZD4547_30min_R2 1 PSVPSADSETPLTQDRPGSPSGSEDKGNPAPELR 34 2 Q96FS4;F6RY50 Q96FS4 SIPA1 Signal-induced proliferation-associated protein 1 1 PSVPSADSET(0.003)PLT(0.01)QDRPGS(0.489)PS(0.115)GS(0.383)EDKGNPAPELR 66.828 7.6327e-06 4477600.0 11743.0 15333.0 12760.0 12156.0 11709.0 15149.0 13850.0 15806.0 14846.0 9282.9 True False 15477.029730426333 20289.0923968427 12590.794062764102 9353.622008327833 10083.407462052002 14201.73063520098 15082.623168994802 13363.545885746722 15630.729251290297 8957.908496494854 1.7277503712481936 2.2649363302585233 1.4055506447393118 1.0441747660168461 1.1256430522814054 1.5853846509771767 1.683721504288249 1.4918154043408405 1.744908340759057 1.0 13.128946214047556 -5.279714075804169 23.66872528651327 1.3990832951747827 1.9963432773577134 0.4434291704103953 0.27354061593796275 340.23105700526935 440655.1763496195 0.07476569361013456 0.15622919648054095 5.2515308876601795e-06 5.279714075804169 0.5972599821829307 PSVPSADSETPLTQDRPGS(ph)PSGSEDKGNPAPELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PSVPSADSETPLTQDRPGSPSGSEDKGNPAPELR 34 2 Q96FS4;F6RY50 Q96FS4 SIPA1 Signal-induced proliferation-associated protein 1 1 PSVPS(0.003)ADS(0.008)ET(0.008)PLT(0.083)QDRPGS(0.575)PS(0.132)GS(0.19)EDKGNPAPELR 43.92 0.005531899999999999 5034500.0 7872.5 8526.2 6305.2 7181.7 7475.4 5285.0 5791.2 7080.8 4051.2 4439.1 True False 9205.158761037426 9372.62478830723 6455.539880604161 6779.332632385549 6010.6490326079065 5007.845296289228 5242.6156113428515 6894.936502727749 4110.441135882581 5243.8736901037355 1.755411992170873 1.7873475491973223 1.2310631914699028 1.2928100547462726 1.1462230762634946 0.9549896874404238 0.9997600859907708 1.3148555648355733 0.7838558628213769 1.0 12.356417220249291 -5.307376976129577 0.9403491345707432 1.0339973119915316 1.9666128047615805 0.7830380477533889 0.14621198895796078 0.4680198609668777 0.5578478087635735 0.052423593056052493 0.3771563416986931 4.927459051579609e-06 5.307376976129577 0.932615492770049 PT(ph)EQDLQHGNSMNSLS(ph)S(ph)VS(ph)LPLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PTEQDLQHGNSMNSLSSVSLPLAK 24 0 P56589 P56589 PEX3 Peroxisomal biogenesis factor 3 4 PT(0.996)EQDLQHGNS(0.053)MNS(0.356)LS(0.81)S(0.81)VS(0.975)LPLAK 42.348 0.042737 0.0 1361.5 4212.5 4793.3 3944.7 6473.3 4177.3 4030.0 4079.0 7036.2 4402.6 True False 1591.9750591492493 4630.68916055737 4907.590450691477 3723.6912478899517 5204.903333972868 3958.235034283631 3648.2492253266487 3971.9305720577477 7139.091113817397 5200.756529037577 0.30610451580663617 0.8903876070149932 0.9436301090602386 0.7159903039296933 1.0007973464845235 0.7610883170906907 0.7014843330883196 0.7637216912349425 1.3727024278020794 1.0 12.344505785089593 -4.761146494947065 24.999998984749357 0.8855037405260417 0.3061038765298272 0.4703594084720819 0.1897564532307851 6.35992443843968 541971.2871173321 0.04605737523755087 0.2610412006374528 1.73321925467751e-05 4.761146494947065 -0.5793998639962146 PT(ph)FPTSNNPRDPS(ph)SSSSMSSR ddPTM_PC-9_AZD4547_30min_R2 1 PTFPTSNNPRDPSSSSSMSSR 21 1 A0A087WZ85;A0A0A0MSX4;A0A087WTM1;Q9Y6N7-6;Q9Y6N7-5;Q9Y6N7-4;Q9Y6N7-3;Q9Y6N7;Q9Y6N7-2 A0A087WZ85 ROBO1 Roundabout homolog 1 2 PT(0.333)FPT(0.333)S(0.333)NNPRDPS(0.807)S(0.03)S(0.03)S(0.03)S(0.03)MS(0.038)S(0.039)R 60.528 0.036074 1115200.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PT(ph)MT(ph)IPGYVEPT(ph)AVATPPTTTTK ddPTM_PC-9_Lapatinib_30min_R1 1 PTMTIPGYVEPTAVATPPTTTTK 23 0 Q14118 Q14118 DAG1 Dystroglycan;Alpha-dystroglycan;Beta-dystroglycan 3 PT(0.727)MT(0.729)IPGY(0.466)VEPT(0.201)AVAT(0.145)PPT(0.127)T(0.183)T(0.21)T(0.21)K 41.615 0.041638999999999995 7515400.0 20768.0 22242.0 23820.0 24325.0 25796.0 26031.0 21588.0 22333.0 25402.0 22654.0 True False 20471.844511615247 22190.500015544396 21861.611547859025 26113.941645821218 24278.729996887312 24917.714811224792 22705.721009104756 23370.672710624865 22540.95926508142 26569.713715442427 0.7704954871123405 0.8351802451919978 0.8228019233475206 0.9828461806362515 0.9137746178565866 0.9378239855381849 0.8545715340511214 0.8795982132484075 0.8483704230497795 1.0 14.697495062645592 -5.618406762136452 8.49806782767095 0.9097735000691426 0.8093489441948751 0.4977228304963278 0.04919006874399323 0.22844191493927696 17.965668983234835 0.013489284726737473 0.023411396714268697 2.407649357270063e-06 5.618406762136452 -0.10042455587426746 PTEATVSLS(ph)SLVDYPHQAR ddPTM_PC-9_AZD4547_30min_R2 2 PTEATVSLSSLVDYPHQAR 19 0 Q92619;K7ES92;F5H1R4;K7ES98;K7EM85;Q92619-2 Q92619 HMHA1 Minor histocompatibility protein HA-1;Minor histocompatibility antigen HA-1 1 PTEATVSLS(0.994)S(0.005)LVDYPHQAR;PTEATVS(0.002)LS(0.992)S(0.006)LVDYPHQAR 160.05 4.2663999999999995e-06 5634800.0 30977.0 26390.0 35413.0 29660.0 26655.0 30798.0 40946.0 38106.0 28711.0 28540.0 True False 40827.041638373215 34920.05141542286 34943.40048155686 22822.345242431988 22954.41334879118 28872.196191360457 44590.1146770875 32217.59328876787 30228.604845331793 27540.823286899926 1.4824190697956736 1.2679378191295008 1.2687856175373686 0.8286733117846796 0.8334686697514115 1.048341797577773 1.6190552552689026 1.1698122802339208 1.0975926365901465 1.0 14.749284066624892 -5.0426615133602635 1.8943637936905176 1.106673218050353 1.4883918219542331 0.23822548541528854 0.21318472182511958 0.843701986243755 4.63244506109804 0.0660858149519938 0.4750922011400009 9.064387988839538e-06 5.0426615133602635 0.38171860390388024 PTEATVSLS(ph)SLVDYPHQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 PTEATVSLSSLVDYPHQAR 19 0 Q92619;K7ES92;F5H1R4;K7ES98;K7EM85;Q92619-2 Q92619 HMHA1 Minor histocompatibility protein HA-1;Minor histocompatibility antigen HA-1 1 PTEATVS(0.001)LS(0.944)S(0.055)LVDYPHQAR;PTEATVSLS(0.968)S(0.032)LVDYPHQAR;PTEAT(0.001)VS(0.097)LS(0.838)S(0.064)LVDYPHQAR 138.46 7.7784e-05 4907500.0 25024.7 29392.7 23555.300000000003 24851.3 27386.0 22275.6 28684.4 22905.699999999997 20525.1 21733.4 True False 29260.88744964541 32310.613006412965 24116.947685972722 23458.96223000167 22019.909892045936 21107.42832204735 25967.205974927972 22304.449645595283 20825.240757825737 25673.493378500254 1.139731434996273 1.2585203162679386 0.9393714883448222 0.9137425080471091 0.8576904423332612 0.822148665585313 1.0114403050686387 0.8687734589432108 0.8111572683468706 1.0 14.647991995561567 -5.343224543094068 4.823148337568999 0.8950426499592211 1.198485918975723 0.7486264840819823 0.06876744200602412 0.0928524699689918 3.7922482134121442 0.017905453810446413 0.03934457487551013 4.537069760695743e-06 5.343224543094068 0.303443269016502 PTEATVSLS(ph)SLVDYPHQAR ddPTM_PC-9_Lapatinib_30min_R1 2 PTEATVSLSSLVDYPHQAR 19 0 Q92619;K7ES92;F5H1R4;K7ES98;K7EM85;Q92619-2 Q92619 HMHA1 Minor histocompatibility protein HA-1;Minor histocompatibility antigen HA-1 1 PTEATVSLS(0.847)S(0.153)LVDYPHQAR;PTEATVSLS(0.966)S(0.034)LVDYPHQAR 168.17 3.7791000000000004e-08 4305600.0 10009.8 17843.6 18355.9 18445.2 17144.2 17049.5 22770.0 16467.199999999997 18272.0 16644.9 True False 9867.0584164275 17802.284240507524 16846.748757823065 19801.721539383423 16135.811862794053 16320.332629325694 23948.919185534323 17232.32622846915 16214.014947309974 19521.948787064877 0.5054340898058985 0.9119112253948339 0.8629644991685265 1.0143311897480194 0.8265471874142781 0.8359991518950939 1.2267688767528542 0.8827154715151789 0.830553093042293 1.0 14.252809457301668 -4.7568529043111205 4.839209211403221 0.933882715134413 0.4735914363548308 0.5472905174156906 0.11665564846270389 0.14991250686861762 8.649617065642007 0.02944730128077982 0.23816317973475493 1.7504394626745622e-05 4.7568529043111205 -0.4602912787795822 PTGGGS(ph)SPPEIR ddPTM_PC-9_AZD4547_30min_R2 1 PTGGGSSPPEIR 12 0 Q13470-2;Q13470 Q13470-2 TNK1 Non-receptor tyrosine-protein kinase TNK1 1 PT(0.005)GGGS(0.812)S(0.183)PPEIR 77.74 0.017235 5343300.0 47755.0 48057.0 47373.0 41660.0 43456.0 54254.0 51367.0 44680.0 47773.0 41772.0 True False 62940.096634293564 63590.4854441446 46744.803067031666 32055.93064058387 37422.88450516115 50861.48880336615 55938.56348893547 37775.73264425939 50298.183249487505 40309.574994407274 1.561418016514095 1.5775528631340674 1.1596451481693182 0.795243577860383 0.9283869777925806 1.2617718944053091 1.3877239712077498 0.9371404349835135 1.2477974093367665 1.0 15.298834951706604 -5.299456372215865 4.688982718693214 1.084462413896961 1.5744953375220896 0.5627444997274642 0.16997942231363583 0.1435932875258142 7.702190310223722 0.048189533929116214 0.1112860407577873 5.018149871750391e-06 5.299456372215865 0.4900329236251286 PTGGGS(ph)SPPEIR ddPTM_PC-9_Lapatinib_30min_R1 3 PTGGGSSPPEIR 12 0 Q13470-2;Q13470 Q13470-2 TNK1 Non-receptor tyrosine-protein kinase TNK1 1 PT(0.007)GGGS(0.783)S(0.211)PPEIR;PT(0.022)GGGS(0.825)S(0.153)PPEIR;PT(0.003)GGGS(0.82)S(0.177)PPEIR 84.605 0.010118 12284500.0 63313.0 116456.0 94080.0 96045.0 107357.0 107214.0 112544.0 113809.0 100005.0 105347.0 True False 62410.14500981775 116186.35328703542 86345.10555930225 103108.46969672746 101042.47233198283 102628.70714804088 118370.97763797869 119096.98162018137 88741.38380066396 123556.0885839458 0.5051159010056828 0.9403531191269197 0.6988332711798183 0.8345073956163161 0.8177862660595079 0.8306244420995363 0.9580343550415625 0.9639102612030741 0.7182275257958799 1.0 16.9148065798298 -4.752913911023062 24.999340061075475 0.8559539360671122 0.5051152438945046 0.5436398624650058 0.09806186105022163 254.76905319016487 747005.9782565181 0.023911990069698304 0.27184842558784444 1.7663879321092245e-05 4.752913911023062 -0.35083869217260766 PTHS(ph)GGGGGGGGGGGGGGGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PTHSGGGGGGGGGGGGGGGGR 21 0 Q13595;Q13595-4;Q13595-3 Q13595 TRA2A Transformer-2 protein homolog alpha 1 PT(0.372)HS(0.628)GGGGGGGGGGGGGGGGR;PT(0.031)HS(0.969)GGGGGGGGGGGGGGGGR 69.152 0.001779 469680.0 1038.13 1870.73 1021.8 797.35 1425.1799999999998 451.09 0.0 815.05 0.0 0.0 True False 1213.8649049978774 2056.4437111761395 1046.1635871980786 752.6770645435788 1145.926209740233 427.43404630143925 0.0 793.6558011168589 0.0 0.0 0.0 PTLLANGGHGVEGSDTTGS(ph)PTEFLEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PTLLANGGHGVEGSDTTGSPTEFLEEK 27 0 E7EVA0;A0A0J9YW37;P27816;P27816-6;P27816-2;P27816-5;H7C456 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 PTLLANGGHGVEGS(0.015)DT(0.25)T(0.25)GS(0.36)PT(0.124)EFLEEK 68.589 0.00015314 5169100.0 9992.2 13745.0 11768.0 10208.0 10328.0 7864.1 10561.0 7899.5 9236.6 7685.0 True False 11683.682105054075 15109.51276245959 12048.59375038852 9636.078854782525 8304.302540168348 7451.692752043165 9560.585624981324 7692.1464952121005 9371.667801069583 9078.22966557347 1.2870000578814416 1.664367758810729 1.327196402188335 1.0614491161558222 0.9147491136581382 0.8208310459804217 1.053133262450613 0.8473178999185619 1.0323232773685922 1.0 13.148195271416931 -5.748265480369003 2.588294995159048 0.9392260855875109 1.481035999309207 0.7923554068657651 0.11156777274475711 0.10489901830162372 1.432270039917108 0.030682642257380315 0.05620620930835095 1.7853958445420859e-06 5.748265480369003 0.5418099137216962 PTLLANGGHGVEGSDTTGSPT(ph)EFLEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PTLLANGGHGVEGSDTTGSPTEFLEEK 27 0 E7EVA0;A0A0J9YW37;P27816;P27816-6;P27816-2;P27816-5;H7C456 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 PTLLANGGHGVEGS(0.001)DT(0.015)T(0.061)GS(0.206)PT(0.717)EFLEEK 78.642 0.0013557 0.0 4708.1 7050.4 5551.7 6088.2 8544.7 4993.3 5543.0 5127.6 6273.7 4344.5 True False 5505.088340786323 7750.317117529654 5684.073582939493 5747.097892210716 6870.427373642187 4731.442557797729 5017.9269121552425 4993.005933141282 6365.440993825668 5132.123458956922 1.0726726246576312 1.510157964731594 1.107548099416679 1.119828456616822 1.3387104633368596 0.9219268779553815 0.9777486750435872 0.9728927943904305 1.2403133020341275 1.0 12.325340161146293 -6.763076890534473 24.99964145282796 1.018080399297111 1.2324604092628522 0.3435296333508887 0.14312746409293875 50.332666982861724 768412.3876915573 0.048457069963386674 0.04499536979891715 1.7255323646187325e-07 6.763076890534473 0.21438000996574114 PTLLANGGHGVEGSDTTGSPT(ph)EFLEEK ddPTM_PC-9_Lapatinib_30min_R1 1 PTLLANGGHGVEGSDTTGSPTEFLEEK 27 0 E7EVA0;A0A0J9YW37;P27816;P27816-6;P27816-2;P27816-5;H7C456 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 PTLLANGGHGVEGS(0.004)DT(0.053)T(0.152)GS(0.345)PT(0.446)EFLEEK 69.7 0.00047676 1889300.0 4443.2 7036.8 7174.3 5753.7 5571.7 6521.4 7552.4 8537.4 6454.8 8184.3 True False 4379.83915321691 7020.5067219397015 6584.456747598866 6176.846291780539 5243.983560383666 6242.4949241258955 7943.426317822986 8934.078771311002 5727.7924519426615 9598.94535010574 0.45628337212782055 0.7313831328211869 0.6859562699277513 0.6434921823690242 0.5463083046228511 0.6503313329163948 0.8275311534860945 0.9307354553500595 0.5967106013245055 1.0 13.228660188229625 -7.237504148208206 4.742946061993441 0.8343203389093065 0.6232994761026857 0.4482129463039273 0.11967544785529748 0.19529503099163542 11.833959302082436 0.04668359074922843 0.034195317505361485 5.787564602711375e-08 7.237504148208206 -0.2110208628066208 PTPEEGPPELNRQS(ph)PNSSSAAASVASR ddPTM_PC-9_Lapatinib_30min_R1 1 PTPEEGPPELNRQSPNSSSAAASVASR 27 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 PTPEEGPPELNRQS(0.422)PNS(0.309)S(0.123)S(0.123)AAAS(0.021)VAS(0.001)R 54.943000000000005 0.0019801 5950500.0 3529.0 7607.6 3811.4 5550.2 8464.0 6077.7 7387.4 8904.6 5759.1 6615.4 True False 3478.675812860658 7589.985069609548 3498.041404429464 5958.380222924438 7966.164160864253 5817.770938810683 7769.88342517419 9318.340223840507 5110.44951198844 7758.86307553359 0.448348653532776 0.9782341814412767 0.4508445851377391 0.7679450152578792 1.0267179718616708 0.7498226070203701 1.0014203562472124 1.2009929977014924 0.658659582240016 1.0 12.921629551061931 -6.036870316912392 6.266065191300271 0.9404020035821578 0.6524447805371495 0.33922015275483197 0.1967138960424059 0.23169940258313293 26.993444566217576 0.05539297320493855 0.07397058219725151 9.186068573690874e-07 6.036870316912392 -0.28795722304500826 PTS(ph)RAPSPSGLMSPSR ddPTM_PC-9_Lapatinib_30min_R1 1 PTSRAPSPSGLMSPSR 16 1 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 PT(0.063)S(0.937)RAPSPSGLMSPSR 80.719 0.037783 13012000.0 57675.0 38929.0 46087.0 40166.0 51215.0 48911.0 54329.0 46990.0 56235.0 74118.0 True False 56852.54392370039 38838.86229229063 42297.90476096467 43119.94162984814 48202.63439256408 46819.19054710978 57141.889786161366 49173.326945428846 49901.22211919745 86929.19754397297 0.6540097634622893 0.4467873095532035 0.4865788015536248 0.4960351970123271 0.5545045365014541 0.5385899314603287 0.6573382867966341 0.5656710096806612 0.5740444353458458 1.0 16.40755320649705 -14.522878745280336 0.24700882429606433 3.7062523910267444 0.5074938657717845 0.8316336571326106 0.0609957268180205 66.97611498376823 0.6641511860451013 91.25513784346582 0.08973205771183895 3.0000000000000132e-15 14.522878745280336 -3.19875852525496 PTS(ph)SPAKGPPQK ddPTM_PC-9_Lapatinib_30min_R1 1 PTSSPAKGPPQK 12 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 PT(0.001)S(0.499)S(0.499)PAKGPPQK 177.36 0.004460899999999999 23627000.0 39749.0 76891.0 61816.0 63206.0 78182.0 63572.0 68117.0 66231.0 61155.0 73348.0 True False 39182.17197092614 76712.9636136688 56733.72709666051 67854.38008903508 73583.48847172597 60853.173753570016 71643.76496095928 69308.33404815277 54267.079909300635 86026.10406993353 0.4554683999065403 0.8917405297269564 0.6594943210556152 0.78876500130558 0.8553623259738401 0.7073803284651878 0.8328142455773382 0.8056663125393855 0.6308210803686413 1.0 16.39248688236171 -14.522878745280336 0.1827696334026297 1.9723629248764734 0.7014468721508839 0.2856658055349869 0.12377977730472708 182.9317153912326 1.7643772131911153 65.4818556531532 0.35158356015794723 3.0000000000000132e-15 14.522878745280336 -1.2709160527255894 PTSS(ph)PAKGPPQK ddPTM_PC-9_Lapatinib_30min_R1 1 PTSSPAKGPPQK 12 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 PT(0.001)S(0.018)S(0.982)PAKGPPQK 141.58 0.00038064 16579000.0 27601.0 52586.0 46261.0 49564.0 54524.0 45130.0 51135.0 49542.0 44594.0 47457.0 True False 27207.404678596493 52464.24034787423 42457.59915262413 53209.101900657086 51317.005518308426 43199.89510316829 53782.52009452342 51843.90218196284 39571.354124361904 55659.87921752235 0.4888153740375221 0.9425863132552019 0.7628043709311176 0.9559686914287494 0.9219747911733388 0.7761406548214083 0.9662708732144011 0.9314411549359202 0.710949335152427 1.0 15.764350157560138 -4.756026303965805 24.999903372909795 0.8818440434692498 0.48881475558915194 0.6140103339379854 0.09428247245495922 111.49877424774934 514894.3473812503 0.022132329672401665 0.185818837056037 1.7537742775686134e-05 4.756026303965805 -0.3930292878800979 PTTQQS(ph)PQDEQEK ddPTM_PC-9_AZD4547_30min_R2 1 PTTQQSPQDEQEK 13 0 Q96QK1;I3L4S0;A0A1W2PP10;A0A3B3ITD4 Q96QK1 VPS35 Vacuolar protein sorting-associated protein 35 1 PTTQQS(1)PQDEQEK 121.31 0.001065 0.0 7230.9 6543.8 7439.3 7624.0 5428.2 6646.7 5852.3 9095.9 8577.7 7783.8 True False 9530.175787936623 8658.95537901645 7340.650021247731 5866.404589625808 4674.588127552367 6231.08079826987 6373.143362592658 7690.33765798834 9031.099710278384 7511.29153120433 1.2687799093331948 1.152791812572359 0.9772820014710255 0.7810114366157763 0.6223414586070344 0.8295618366540493 0.8484750373642886 1.0238369295134124 1.2023364654081499 1.0 12.874845278348753 -5.236663828256143 2.4951226907429764 0.885482351265932 1.249004158157853 0.40630093013987234 0.1485291813451604 0.3181553591147518 3.7536887789458664 0.045108380057033964 0.15727104669544367 5.798773849824945e-06 5.236663828256143 0.36352180689192104 PTTQQS(ph)PQDEQEK ddPTM_PC-9_Lapatinib_30min_R1 1 PTTQQSPQDEQEK 13 0 Q96QK1;I3L4S0;A0A1W2PP10;A0A3B3ITD4 Q96QK1 VPS35 Vacuolar protein sorting-associated protein 35 1 PTTQQS(1)PQDEQEK 124.09 0.0011077 0.0 6656.6 7887.1 6417.3 7453.9 9256.3 9207.9 11393.0 8509.4 10439.0 7980.7 True False 6561.675663329068 7868.8379045319825 5889.694365494358 8002.084671481475 8711.862632585986 8814.09958166327 11982.873793622866 8904.777789091984 9263.249892456695 9360.15336138569 0.701022238631106 0.8406740360680446 0.6292305412207947 0.8549095685219452 0.930739304820137 0.941661876826174 1.2802005833640429 0.9513495607697723 0.9896472349129706 1.0 13.19231645249406 -6.366476005544537 1.5727387045663788 1.0475709515875251 0.7365935638741393 0.627148539310167 0.10307311390440169 0.2531009420061118 1.2522898930896045 0.03927798925770755 0.04897335299708506 4.300549932009728e-07 6.366476005544537 -0.3109773877133858 PVS(ph)PETQADLQR ddPTM_PC-9_AZD4547_30min_R2 1 PVSPETQADLQR 12 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 PVS(0.97)PET(0.03)QADLQR 104.41 0.0019138999999999998 5402300.0 11138.0 13767.0 13820.0 11746.0 10838.0 12651.0 13599.0 16915.0 10973.0 11854.0 True False 14679.652315208074 18216.913521641785 13636.737770172409 9038.141173890974 9333.330777497618 11859.930970092259 14809.284655246245 14301.175418031497 11553.010378176508 11438.995068076794 1.2832991209319686 1.5925274390999928 1.1921272532260228 0.7901167121851492 0.815922266069025 1.036798328831366 1.2946316146752292 1.2502125696288033 1.0099672488204756 1.0 13.481672694429378 -5.504172592681222 9.959907071147656 1.0373830471377656 1.4269947464651211 0.4936332406925872 0.16488249172112565 0.35743565196298904 182.3987162061292 0.048936513480649056 0.09611839191292793 3.1320407747133853e-06 5.504172592681222 0.3896116993273555 PVS(ph)PETQADLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PVSPETQADLQR 12 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 PVS(0.853)PET(0.147)QADLQR;PVS(0.994)PET(0.006)QADLQR 96.37100000000001 0.0043046000000000004 9717900.0 22765.0 32998.0 27125.0 21205.0 25712.0 21009.0 23287.0 18499.6 17708.6 19371.2 True False 26618.664870754776 36273.82336381531 27771.762872135336 20016.95259753756 20673.918175136387 19907.251055769233 21081.086776720025 18014.00510194642 17967.554773620235 22883.045217665185 1.1632483621631695 1.5851833975231913 1.2136392952934505 0.8747503842751198 0.9034600936407099 0.8699563745301387 0.9212535559054837 0.7872206225437173 0.7851907210212431 1.0 14.481991434641497 -5.652271201010058 3.568790863254641 0.86961062230285 1.380552386851621 0.771235010758355 0.11249463411401268 0.09289840274281061 2.268074842157474 0.029681131226073153 0.054499598917308684 2.2270440074774793e-06 5.652271201010058 0.5109417645487709 PVS(ph)PETQADLQR ddPTM_PC-9_Lapatinib_30min_R1 2 PVSPETQADLQR 12 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 PVS(0.989)PET(0.011)QADLQR;PVS(0.961)PET(0.039)QADLQR 109.95 0.0012506 9423500.0 15814.400000000001 25294.0 22582.0 19727.6 22136.3 23118.0 23205.0 21850.0 24601.0 17798.2 True False 15588.883755994231 25235.433297058727 20725.395129040815 21178.4335133444 20834.286355640274 22129.297030690126 24406.441357063 22865.230767346664 21830.176319985367 20874.595155389237 0.7467873575488058 1.2089064774290315 0.9928525547327847 1.0145554132041081 0.9980690020836855 1.0601066447498007 1.1691935185033726 1.0953616392145216 1.045777231006534 1.0 14.34946059759238 -6.895599008521986 4.65124274961171 1.0891070248875574 1.0058725364458843 0.10977814527420204 0.11182049322614682 0.4930902501629458 18.129638766911594 0.038532448804172295 0.033841488822498336 1.271747789637262e-07 6.895599008521986 -0.08323448844167314 PVS(ph)PSSLLDTAISEEAR ddPTM_PC-9_AZD4547_30min_R2 1 PVSPSSLLDTAISEEAR 17 0 A0A0B4J2F2;P57059 A0A0B4J2F2 LOC102724428;SIK1 Serine/threonine-protein kinase SIK1 1 PVS(0.433)PS(0.433)S(0.134)LLDTAISEEAR 133.9 9.242799999999999e-06 0.0 685.56 0.0 0.0 0.0 0.0 0.0 488.56 0.0 0.0 548.37 True False 903.5538194661558 0.0 0.0 0.0 0.0 0.0 532.0408935338704 0.0 0.0 529.1717332108378 1.7074869324249278 0.0 0.0 0.0 0.0 0.0 1.0054219833429565 0.0 0.0 1.0 9.047592188946663 -10.828415513004405 5.029318323365932 1.0002351110632544 0.2689455509012563 0.12111534334946084 0.558401361687644 0.0014431966825375342 0.00019928054608545824 0.5300626683199853 0.1285187184882542 1.484514647223163e-11 10.828415513004405 -0.731289560161998 PVS(ph)PSSLLDTAISEEAR ddPTM_PC-9_Lapatinib_30min_R1 1 PVSPSSLLDTAISEEAR 17 0 A0A0B4J2F2;P57059 A0A0B4J2F2 LOC102724428;SIK1 Serine/threonine-protein kinase SIK1 1 PVS(0.692)PS(0.295)S(0.012)LLDTAISEEAR 224.67 6.4486e-29 637750.0 1678.2 1423.4 3724.9 1976.0 2028.5 1699.8 2167.4 801.09 784.23 2195.2 True False 1654.2685602558126 1420.1042047534354 3418.6531005298075 2121.321631742765 1909.1876181844448 1627.103516427332 2279.617366830351 838.3115659228258 695.9017590919931 2574.637395079863 0.6425248710428595 0.5515744498496205 1.3278192521645418 0.8239302496719013 0.741536506007761 0.631973853691681 0.8854129793914686 0.32560374036547474 0.27029117203916275 1.0 11.330153546023443 -7.754379925092678 24.920741978731893 0.47346057758786486 0.8035058192139789 0.15942901576766721 0.27295816320618954 228.1443758088762 805385.9377900045 0.13161944614138632 0.07389704361547404 1.7604353264189848e-08 7.754379925092678 0.33004524162611404 PVS(ph)SAASVYAGAGGSGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PVSSAASVYAGAGGSGSR 18 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 PVS(0.814)S(0.109)AAS(0.077)VYAGAGGSGSR;PVS(0.751)S(0.244)AAS(0.005)VYAGAGGSGSR 133.23 3.9678e-05 45857000.0 24234.5 24665.2 29695.0 32057.0 40448.0 24406.0 28550.0 25667.0 26387.0 26256.0 True False 28336.922196806816 27113.798049371995 30403.04141891461 30260.95022019628 32522.504758397474 23126.106395692503 25845.53731589971 24993.26844643445 26772.859955700464 31016.004957618374 0.9136225711701951 0.8741873134989976 0.980237185945084 0.9756559641238827 1.0485716907395923 0.7456184775341965 0.8332967882619371 0.8058184308580794 0.863194985694775 1.0 14.920725250352511 -6.7619684283303245 24.99999750902663 0.8364313383465904 0.9559391394162016 0.3443991034116507 0.07395876522061938 15.297816528690083 722869.619787177 0.025079218264759607 0.02346492934332857 1.7299421153048262e-07 6.7619684283303245 0.11950780106961112 PVS(ph)SAASVYAGAGGSGSR ddPTM_PC-9_Lapatinib_30min_R1 2 PVSSAASVYAGAGGSGSR 18 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 PVS(0.785)S(0.201)AAS(0.002)VYAGAGGS(0.012)GSR;PVS(0.788)S(0.139)AAS(0.072)VYAGAGGSGSR 230.48 2.128e-35 290448000.0 96309.6 177802.0 261376.0 231854.0 261622.7 253959.0 221146.0 217735.0 286092.0 229359.0 True False 94936.20744298233 177390.31039312202 239886.67422053675 248905.3166022712 246234.56715601822 243097.76557734344 232595.8578043115 227851.7629806971 253869.30627768167 269003.3975483427 0.3529182467887652 0.6594352042012523 0.8917607599265605 0.9252868880867585 0.9153585768810497 0.9036977517492367 0.864657695494391 0.8470218780034173 0.9437401482338479 1.0 18.037264868762172 -4.87013147783339 1.8526294194810942 0.9075998864906136 0.2337740132287233 0.9491568583307995 0.04068956594447502 0.1361602943030273 0.5696278708066896 0.011287719159600829 0.15201023572439876 1.3485545608640377e-05 4.87013147783339 -0.6738258732618904 down PVS(ph)VAGSPLSPGPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PVSVAGSPLSPGPVR 15 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 PVS(0.684)VAGS(0.311)PLS(0.005)PGPVR 164.92 0.0002942 9664300.0 51876.0 40594.0 32887.0 36376.0 39214.0 32024.0 37825.0 33359.0 34974.0 30911.0 True False 60657.58220229634 44623.90404360019 33671.15080464205 34337.97065258321 31530.298200054385 30344.605064969965 34241.942170714756 32483.36159678216 35485.428585692505 36514.919608658616 1.6611725522712881 1.2220731832863936 0.922120359718874 0.9403819321141488 0.8634908288988195 0.8310193583932878 0.9377520897675787 0.8895914860258799 0.9718062908531779 1.0 15.156198433884427 -4.808758568772174 1.734219210719111 0.9069918615776529 1.897812981120768 0.956653986635557 0.049021565191968666 0.15251535801560173 0.4841958963790176 0.013443115196078983 0.24922025627524683 1.5532502465728204e-05 4.808758568772174 0.9908211195431151 PVSMVPNIPGIPGPPVNS(ph)SGSISPSGHPIPSEAK ddPTM_PC-9_AZD4547_30min_R2 2 PVSMVPNIPGIPGPPVNSSGSISPSGHPIPSEAK 34 0 K7ELQ4;P17544-2;P17544;P17544-3;P17544-1 K7ELQ4 ATF7 Cyclic AMP-dependent transcription factor ATF-7 1 PVSMVPNIPGIPGPPVNS(0.227)S(0.227)GS(0.227)IS(0.227)PS(0.063)GHPIPS(0.03)EAK;PVSMVPNIPGIPGPPVNS(0.24)S(0.24)GS(0.24)IS(0.24)PS(0.037)GHPIPS(0.002)EAK 59.038000000000004 0.00032087 11238700.0 15420.1 10336.8 38861.0 56091.0 49359.0 53039.0 32180.0 50677.0 40415.0 55393.0 True False 20323.371041994975 13677.968452858775 38345.67774867369 43160.08654731131 42506.35484835806 49722.46294543697 35043.95765907961 42846.03409160994 42551.25439114221 53453.707930316974 0.38020507517436986 0.2558843714020657 0.7173623539579643 0.8074292358460038 0.7951993695885411 0.9301967042259425 0.655594513756902 0.8015540128191789 0.7960393401822122 1.0 15.706002406581076 -5.354175734805159 4.007125293819748 0.8110589276194894 0.31671495384033277 0.824149336599773 0.09215750963532732 0.08090540081214177 2.3250981897439384 0.023585660972994714 0.05390972292225026 4.424093177107838e-06 5.354175734805159 -0.4943439737791566 PVSMVPNIPGIPGPPVNSSGSIS(ph)PSGHPIPSEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PVSMVPNIPGIPGPPVNSSGSISPSGHPIPSEAK 34 0 K7ELQ4;P17544-2;P17544;P17544-3;P17544-1 K7ELQ4 ATF7 Cyclic AMP-dependent transcription factor ATF-7 1 PVSMVPNIPGIPGPPVNS(0.107)S(0.107)GS(0.131)IS(0.499)PS(0.119)GHPIPS(0.037)EAK 57.144 0.00053127 4434900.0 12996.0 15443.0 26968.0 36122.0 38164.0 36894.0 40189.0 26317.0 33999.0 31489.0 True False 15195.966117299762 16976.07898076852 27611.01939670953 34098.20144910407 30686.038162566314 34959.21369182491 36382.00697683691 25626.2066351664 34496.17105521129 37197.706433213134 0.4085189000720638 0.4563743469304575 0.7422774693456952 0.9166748361307143 0.8249443609557423 0.9398217536501251 0.9780712432407417 0.6889189977660891 0.9273736034544944 1.0 15.182926048747293 -5.351113396538987 2.3652695037437907 0.8861834477012497 0.40574817627563253 0.8264573441372405 0.08407953301948157 0.11884285326578066 1.2623033328871107 0.02324959540712895 0.06907691527889885 4.455399004326166e-06 5.351113396538987 -0.48043527142561715 PVSS(ph)AASVYAGAGGSGSR ddPTM_PC-9_AZD4547_30min_R2 1 PVSSAASVYAGAGGSGSR 18 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 PVS(0.036)S(0.842)AAS(0.097)VYAGAGGS(0.022)GS(0.002)R 156.06 1.3283000000000001e-17 0.0 13633.0 6701.0 13559.0 19985.0 11690.0 13536.0 22758.0 15862.0 6465.0 15856.0 True False 17968.010415984172 8866.9672048029 13379.198800706788 15377.767015172063 10067.04528408813 12689.591780188817 24783.4179119122 13410.892372498713 6806.7267014409135 15300.886266190782 1.1743117426921037 0.5795067717348877 0.8744067871591071 1.0050245945001994 0.6579387042652897 0.8293370435821129 1.6197374113337641 0.876478142454516 0.4448583293165982 1.0 13.901327599448253 PVSS(ph)AASVYAGAGGSGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PVSSAASVYAGAGGSGSR 18 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 PVS(0.057)S(0.924)AAS(0.02)VYAGAGGSGSR 168.16 1.0287000000000001e-07 6697200.0 18817.0 16310.0 17407.0 18723.0 11579.0 11922.0 17864.0 17436.0 14398.0 13092.0 True False 22002.34644730914 17929.149010965146 17822.048896415108 17674.011010785 9310.178070546992 11296.789332518476 16171.792595840012 16978.32347496908 14608.5435116601 15465.475963785015 1.4226750278382183 1.1593014694762211 1.1523763599742032 1.1428042080419405 0.6019975131931486 0.7304520959440103 1.0456705395753065 1.0978209474268137 0.9445906188641355 1.0 13.91676361388356 -6.021435055824228 22.527891795448486 0.9036517588638415 1.2214619566048073 0.5068867456215296 0.15457905251201 201.98721906920525 212285.97633128005 0.050029128741258325 0.06540857429534744 9.518421754653384e-07 6.021435055824228 0.31781019774096575 PVSS(ph)AASVYAGAGGSGSR ddPTM_PC-9_Lapatinib_30min_R1 3 PVSSAASVYAGAGGSGSR 18 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 PVS(0.05)S(0.847)AAS(0.102)VY(0.001)AGAGGSGSR;PVS(0.045)S(0.902)AAS(0.053)VYAGAGGSGSR;PVS(0.236)S(0.382)AAS(0.382)VYAGAGGSGSR 237.34 2.0593e-43 1003595000.0 223788.0 300922.0 284179.0 334423.0 249901.0 276674.0 294451.0 294468.0 232690.0 206293.0 True False 220596.74208230726 300225.2335975918 260814.89958266309 359017.58302242437 235202.31450426942 264841.2979785947 309696.2320201918 308150.0582882857 206482.00186567177 241950.47018185598 0.9117433907712652 1.240854102791927 1.0779681452432315 1.4838474285773358 0.9721093508414574 1.0946095611202302 1.2799984715359982 1.2736080159574497 0.8534060781550653 1.0 17.884352217240583 -8.265505600888373 24.973915818292667 0.9267030244557081 1.1717867494759286 0.26359003141091963 0.1603827574062984 476.2893153843486 2925210.370884539 0.13285376415838993 0.03911302232965173 5.426182533956068e-09 8.265505600888373 0.24508372502022058 PVSSAAS(ph)VYAGAGGSGSR ddPTM_PC-9_AZD4547_30min_R2 13 PVSSAASVYAGAGGSGSR 18 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 PVSSAAS(0.644)VY(0.001)AGAGGS(0.276)GS(0.08)R;PVS(0.011)S(0.025)AAS(0.964)VYAGAGGSGSR;PVSSAAS(1)VYAGAGGSGSR;PVS(0.002)SAAS(0.998)VYAGAGGSGSR;PVS(0.029)S(0.011)AAS(0.639)VY(0.308)AGAGGS(0.006)GS(0.007)R;PVS(0.01)S(0.005)AAS(0.979)VYAGAGGS(0.002)GS(0.005)R;PVSSAAS(0.994)VYAGAGGS(0.006)GSR;PVSS(0.001)AAS(0.999)VYAGAGGSGSR;PVS(0.003)S(0.026)AAS(0.893)VY(0.024)AGAGGS(0.007)GS(0.047)R;PVSSAAS(1)VYAGAGGSGSR;PVSS(0.002)AAS(0.913)VYAGAGGS(0.076)GS(0.009)R;PVSSAAS(1)VYAGAGGSGSR;PVSS(0.001)AAS(0.999)VYAGAGGSGSR 213.64 2.3014e-27 2232753200.0 424834.9 313975.3 546857.1 534343.8999999999 436383.3 424982.0 519785.0 373105.0 382532.7 401747.2 True False 559923.5610851306 415461.6756033659 539605.4175439187 411159.16938595934 375799.0113190606 398407.80835758004 566044.8580430306 315450.19534996396 402752.5975660147 387682.1528103311 1.4442851109503267 1.071655407894481 1.391875828258502 1.060557382911341 0.9693482369380976 1.027666106034281 1.4600745841399652 0.8136825310715148 1.0388731971447152 1.0 18.5645147956887 -1.5228787453714396 0.35512859180412804 1.028077587338543 5.197652649724335 0.2657446494836506 0.18096825024607027 94.99274739028066 1.3316966070858074 0.15167196649437287 266.51101242041733 0.02999999999370689 1.5228787453714396 4.169575062385793 PVSSAAS(ph)VYAGAGGSGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 14 PVSSAASVYAGAGGSGSR 18 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 PVSS(0.001)AAS(0.984)VY(0.001)AGAGGS(0.001)GS(0.013)R;PVS(0.013)S(0.04)AAS(0.945)VYAGAGGS(0.001)GS(0.001)R;PVSSAAS(0.999)VY(0.001)AGAGGSGSR;PVS(0.001)SAAS(0.999)VYAGAGGSGSR;PVSS(0.001)AAS(0.971)VY(0.018)AGAGGS(0.002)GS(0.008)R;PVS(0.001)SAAS(0.999)VYAGAGGSGSR;PVSS(0.003)AAS(0.997)VYAGAGGSGSR;PVSS(0.001)AAS(0.977)VY(0.019)AGAGGS(0.003)GSR;PVSSAAS(0.893)VYAGAGGS(0.104)GS(0.002)R;PVS(0.009)S(0.006)AAS(0.969)VYAGAGGS(0.015)GSR;PVSSAAS(1)VYAGAGGSGSR;PVSSAAS(0.991)VY(0.002)AGAGGS(0.005)GS(0.002)R;PVSSAAS(1)VYAGAGGSGSR;PVS(0.002)S(0.005)AAS(0.993)VYAGAGGSGSR 233.57 3.5127e-43 1861286100.0 407138.39999999997 395442.89999999997 302941.9000000001 484909.80000000005 357857.00000000006 363070.7 439957.3 384726.3999999999 359577.49999999994 294198.10000000003 True False 476058.88977005513 434699.85772091796 310165.18380955356 457741.8760047824 287737.4897479685 344030.63334256166 398281.35952898354 374627.7396513161 364835.6406837041 347533.8866591214 1.369820060847757 1.2508128686377376 0.8924746498570342 1.317114369493869 0.8279408161144177 0.9899196784801712 1.146021653766494 1.0779603199349872 1.0497843654640595 1.0 18.406794130637117 -5.057891146286549 5.467240386982308 1.0454072901068048 1.345110944914774 0.435239070643476 0.12718028493973557 0.16385706355848148 10.401327623467063 0.03134712283916154 0.09184500953310304 8.752031129682489e-06 5.057891146286549 0.29970365480796923 PVSSAAS(ph)VYAGAGGSGSR ddPTM_PC-9_Lapatinib_30min_R1 7 PVSSAASVYAGAGGSGSR 18 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 PVSSAAS(1)VYAGAGGSGSR;PVSSAAS(1)VYAGAGGSGSR;PVS(0.001)S(0.01)AAS(0.978)VYAGAGGS(0.01)GS(0.001)R;PVSSAAS(1)VYAGAGGSGSR;PVSS(0.004)AAS(0.996)VYAGAGGSGSR;PVSS(0.003)AAS(0.982)VY(0.004)AGAGGS(0.01)GS(0.001)R;PVS(0.002)S(0.019)AAS(0.937)VY(0.002)AGAGGS(0.032)GS(0.008)R 171.25 7.3602e-25 202595500.0 98876.6 148943.4 137478.4 145148.99999999997 136355.69999999998 148905.49999999997 147674.7 131628.4 98892.3 92948.40000000001 True False 97466.60155225238 148598.5307083552 126175.4566339708 155823.7416628694 128335.52581162054 142537.15888067425 155320.57338814356 137744.33599709885 87754.0077919144 109014.40709404227 0.8940708310982413 1.3631091033698446 1.1574200144493232 1.429386682151531 1.177234543879239 1.3075075366663533 1.4247710695170306 1.2635424956104422 0.804976242417322 1.0 16.73415928530705 -8.251547861323271 24.346219795282654 0.9024881234171894 1.2636852117218875 0.44808381105639905 0.154793122754632 352.3154372487542 867169.4459870793 0.10227899929554347 0.03757586218245938 5.60340661747899e-09 8.251547861323271 0.3611970883046981 PVSSAASVYAGAGGS(ph)GSR ddPTM_PC-9_AZD4547_30min_R2 4 PVSSAASVYAGAGGSGSR 18 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 PVSSAASVYAGAGGS(0.622)GS(0.378)R;PVSSAAS(0.007)VYAGAGGS(0.93)GS(0.063)R;PVSSAASVYAGAGGS(0.998)GS(0.002)R;PVS(0.033)S(0.033)AAS(0.101)VYAGAGGS(0.811)GS(0.023)R 264.1 4.9911e-78 287252400.0 92898.6 84780.3 103196.3 118039.1 116294.6 125187.1 93559.1 101346.1 96739.7 114255.8 True False 122438.4223890814 112183.87400587236 101827.84963473547 90827.00918091554 100149.10218091657 117359.1308470504 101885.67865200761 85685.38894669616 101853.16304398824 110255.7392187591 1.1104947756610706 1.0174878405493943 0.9235605362247692 0.8237848643933637 0.9083345945575686 1.0644265022267676 0.9240850351550008 0.7771512807753911 0.9237901243571616 1.0 16.75049422978367 -5.020852225402027 2.4079210728183065 0.9115870953549967 1.1144195989296617 0.3975113305890141 0.07582771503043763 0.3733660352300686 3.7083958564425665 0.02157830195706913 0.1274530821692237 9.53120421026842e-06 5.020852225402027 0.20283250357466498 PVSSAASVYAGAGGS(ph)GSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 PVSSAASVYAGAGGSGSR 18 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 PVSSAASVYAGAGGS(0.952)GS(0.048)R;PVSSAAS(0.001)VYAGAGGS(0.983)GS(0.016)R;PVSSAAS(0.108)VYAGAGGS(0.853)GS(0.039)R;PVSSAASVYAGAGGS(0.592)GS(0.408)R;PVSS(0.001)AAS(0.068)VY(0.31)AGAGGS(0.501)GS(0.12)R 205.15 4.0028999999999996e-20 327812700.0 204927.9 180966.3 189156.19999999998 234736.4 276488.29999999993 207114.5 222738.3 256663.1 182899.3 152256.5 True False 239618.14595947965 198931.43829938857 193666.40118688357 221584.8805336773 222312.40240286832 196253.05101576052 201638.91573835633 249925.965582034 185573.85625101958 179859.39818820878 1.3322525726942442 1.1060386073972204 1.0767655354001955 1.2319894471225021 1.2360343948790253 1.091147045929716 1.1210919071760541 1.3895630036552553 1.0317718068690025 1.0 17.45651002098419 -8.495001120377909 24.88405764896348 0.999999830636241 1.1887203038058112 0.34949481671258775 0.09925442964708658 621.5023029579568 554764.7313415351 0.09430736492742943 0.024350056924833045 3.1988868573028924e-09 8.495001120377909 0.1887204731695702 PVSSAASVYAGAGGS(ph)GSR ddPTM_PC-9_Lapatinib_30min_R1 2 PVSSAASVYAGAGGSGSR 18 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 PVSSAAS(0.108)VYAGAGGS(0.88)GS(0.012)R;PVSSAASVYAGAGGS(0.697)GS(0.303)R 190.37 4.7841e-11 177752600.0 16217.9 19921.2 19186.9 16114.8 21292.3 19756.5 18299.9 28111.5 22352.4 17356.6 True False 15986.629772001386 19875.073685354888 17609.42714557583 17299.936149396908 20039.92877627243 18911.560549650898 19247.37927990162 29417.662916076253 19834.83733079308 20356.665183784244 0.7853265565686098 0.9763423186420052 0.8650447893402101 0.8498413661181463 0.9844406534836502 0.9290107381986864 0.9455074839681373 1.4451120873918897 0.9743657495822625 1.0 14.31321361891626 -7.55222996024231 24.999680437000453 1.1649055344623638 0.9050085252598432 0.4003730570457642 0.13151172031065628 178.55202814637795 152078.3476118044 0.05713996363720368 0.03299031140037366 2.8039485455665413e-08 7.55222996024231 -0.25989700920252057 PVSSAASVYAGAGGS(ph)GSRISVSR ddPTM_PC-9_Lapatinib_30min_R1 1 PVSSAASVYAGAGGSGSRISVSR 23 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 PVSSAASVY(0.001)AGAGGS(0.325)GS(0.325)RIS(0.325)VS(0.025)R 65.881 0.0073779 0.0 13548.0 8105.4 8533.3 7593.0 4349.6 6440.6 4201.2 3758.9 6559.2 4889.5 True False 13354.803035601084 8086.632444294288 7831.725013490573 8151.414549505473 4093.765079642623 6165.150551771901 4418.717579370522 3933.5522165391053 5820.433824561923 5734.643560150781 2.3287939163999143 1.4101368915911603 1.3656864513624023 1.4214335143945978 0.7138656547182133 1.075071272888284 0.7705304668062648 0.6859279352378232 1.0149599994334932 1.0 12.48548810220506 -1.5228787452888781 0.4913960770075744 0.8450051262002948 43.3121375163244 0.8291347996543588 0.1923402415485443 39.395118886149184 0.42851739356801605 0.10703409306637027 1719.381432682296 0.02999999999941004 1.5228787452888781 42.46713239012411 up PVSSAASVYAGAGGSGS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PVSSAASVYAGAGGSGSR 18 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 PVS(0.006)S(0.02)AAS(0.017)VYAGAGGS(0.223)GS(0.735)R;PVSSAASVYAGAGGS(0.031)GS(0.969)R 262.17 1.8062999999999996e-66 377050000.0 181291.0 166918.0 148094.0 187444.0 255857.0 171442.0 167990.0 215134.0 153993.0 139365.0 True False 211979.9856395343 183488.51591736887 151625.1226096227 176942.12038164743 205723.65753484287 162451.27971360798 152076.77105772324 209486.9604533146 156244.8562988665 164630.77128726683 1.2876085313944565 1.1145456859774827 0.9210011070472944 1.0747815793980477 1.2496063519976615 0.9867613353407922 0.9237445094171495 1.2724654013056738 0.9490622869416823 1.0 17.328874490843134 -4.8159400273989235 3.9089887965515904 1.0564682188326557 1.3012909953721403 0.2692588657752797 0.11845668385801386 0.30905014251350826 8.314695571389118 0.02946271829158404 0.19927485906296846 1.5277770174820606e-05 4.8159400273989235 0.2448227765394846 PVSSAASVYAGAGGSGS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 PVSSAASVYAGAGGSGSR 18 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 PVSSAASVYAGAGGS(0.201)GS(0.799)R 248.94 1.0485e-53 184150000.0 31507.0 51488.0 42939.0 42311.0 40885.0 33047.0 31418.0 37566.0 38096.0 30484.0 True False 31057.704402323816 51368.782699413285 39408.72116933329 45422.69208535838 38480.22468300273 31633.656846319587 33044.67031054536 39311.45350142542 33805.2273113354 35753.11878262326 0.8686711945649476 1.4367636851971513 1.1022456924369552 1.2704539808548037 1.07627602830847 0.8847803470978365 0.9242458122731866 1.0995251558454693 0.9455182781918713 1.0 15.125781474754392 -6.519560196199351 6.854111786271214 0.9743368001803627 1.1829823605760446 0.29834812573716574 0.1432082551457924 0.15981323540732284 42.214823469673696 0.04381690666904037 0.04617227883307173 3.02301153130095e-07 6.519560196199351 0.20864556039568183 PVSSAASVYAGAGGSGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PVSSAASVYAGAGGSGSR 18 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 0 155.09 1.725e-13 0.0 7481.4 7680.0 7909.7 10368.0 4938.8 4006.8 5840.8 6645.3 4324.8 5129.7 False True 8747.853255614536 8442.419644648206 8098.297245704294 9787.114573509523 3971.0775934724447 3796.676354431725 5287.517140269951 6470.867916277358 4388.042018282235 6059.674003317142 1.443617800367784 1.393213502909021 1.336424573544911 1.6151222934025715 0.6553285855474448 0.6265479549482986 0.8725745209025266 1.0678574313956697 0.7241382978490536 1.0 12.565024466735167 -6.262275272444665 24.999744368815993 0.8203160054036167 1.4353409090700109 0.8127390667894023 0.14637631012992874 33.41651160714308 999412.5409562807 0.04662170372510755 0.0560285490552668 5.466693531244486e-07 6.262275272444665 0.6150249036663942 PVSSAASVYAGAGGSGSR ddPTM_PC-9_Lapatinib_30min_R1 2 PVSSAASVYAGAGGSGSR 18 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ; 206.67 1.4835e-19 61019000.0 9816.0 7956.400000000001 8768.3 9204.7 7540.900000000001 9124.3 7769.1 7315.8 9203.8 9432.5 False True 9676.022039966065 7937.97744463976 8047.404220616802 9881.644343979066 7097.359087979822 8734.074958782148 8171.345983501744 7655.718775640951 8167.1711236893325 11062.895056983783 0.8746374244830052 0.7175316590957512 0.7274229918267766 0.893224087644308 0.6415462726006247 0.7894927063660884 0.738626366914991 0.6920176623033272 0.7382489919339479 1.0 13.433441354435464 -10.342888164581106 4.213801678949831 1.0000025299007538 0.7540619482681576 0.4947734058484815 0.07362170791903418 210976993.93475097 469399738.66977 8709.669224995276 0.017581053417023818 4.540585264660437e-11 10.342888164581106 -0.24594058163259613 PVSSAASVYAGAGGSGSRIS(ph)VSR ddPTM_PC-9_AZD4547_30min_R2 1 PVSSAASVYAGAGGSGSRISVSR 23 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 PVSSAASVYAGAGGS(0.235)GS(0.235)RIS(0.505)VS(0.024)R 105.77 1.0908e-06 11157000.0 15077.0 5391.8 12531.0 31937.0 22678.0 13262.0 11083.0 11903.0 10699.0 18343.0 True False 19871.172378918316 7134.5939076042805 12364.830752390055 24574.4180717313 19529.55115077421 12432.725043503557 12069.36552938408 10063.664853729175 11264.527297558603 17700.81715317468 1.1226132786391942 0.40306579328314657 0.698545758955111 1.3883211073859278 1.1033135352890495 0.7023814175309822 0.681853579128092 0.5685423879950217 0.6363845917440193 1.0 14.111528343000122 -6.8734039651754335 9.485074230434545 0.6868306750303129 0.9240832129023049 0.14269473183132508 0.2690836346336836 0.614230105273605 48.93685395360133 0.10203280601136934 0.09000927207995144 1.338431147511835e-07 6.8734039651754335 0.23725253787199196 PVSSAASVYAGAGGSGSRIS(ph)VSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PVSSAASVYAGAGGSGSRISVSR 23 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 PVSSAASVYAGAGGS(0.018)GS(0.073)RIS(0.844)VS(0.065)R 133.8 2.8551000000000002e-08 0.0 15124.0 6650.5 7301.2 17434.0 14922.0 14303.0 10853.0 18469.0 10384.0 13938.0 True False 17684.19448738395 7310.717688376682 7475.288297955195 16457.22950179061 11998.141218473282 13552.925501007532 9824.925271084398 17984.208319523055 10535.846355402044 16464.84906685271 1.0740574915433658 0.4440197209639008 0.45401499082093394 0.9995372222951355 0.7287124934918552 0.8231430149148766 0.5967212472578379 1.092278966330104 0.6398993584832171 1.0 14.007101666368762 -8.989310165493695 0.2636592087887143 1.058616450363143 0.6776620849668764 0.083481063665654 0.22597720621338424 9.22558569136951 1.4701172321603004 1.0930630311217164 0.41919522889754113 1.0249196851619173e-09 8.989310165493695 -0.3809543653962666 PVSSAASVYAGAGGSGSRIS(ph)VSR ddPTM_PC-9_Lapatinib_30min_R1 1 PVSSAASVYAGAGGSGSRISVSR 23 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 PVSSAASVYAGAGGS(0.081)GS(0.242)RIS(0.609)VS(0.068)R 76.133 0.00016965 4629700.0 10929.0 7314.4 6747.8 5420.6 5044.5 5642.0 3264.8 1422.6 6414.5 6526.4 True False 10773.150455866862 7297.4639561954 6193.021931261254 5819.249006591516 4747.792427868589 5400.704812144373 3433.835369210915 1488.69918945663 5692.031462320477 7654.47954411863 1.4074308244960279 0.9533586070920335 0.8090715894615857 0.7602409769404603 0.6202632589849413 0.7055613358185849 0.4486046829727731 0.19448731698557897 0.7436209646276979 1.0 12.902088571643153 -2.5181283917709227 0.5688567935890227 0.5628946816021779 12.831523279583646 0.5777811286167185 0.2008988249201894 29.084572867582605 0.8202386812138918 0.09543494646215087 396.3240440972009 0.0030329943984754447 2.5181283917709227 12.268628597981468 PVSVAGS(ph)PLSPGPVR ddPTM_PC-9_AZD4547_30min_R2 5 PVSVAGSPLSPGPVR 15 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 PVS(0.015)VAGS(0.855)PLS(0.13)PGPVR;PVS(0.005)VAGS(0.825)PLS(0.169)PGPVR;PVS(0.016)VAGS(0.568)PLS(0.417)PGPVR;PVSVAGS(0.729)PLS(0.271)PGPVR;PVS(0.002)VAGS(0.884)PLS(0.114)PGPVR 104.09 0.0011871 102701000.0 264540.0 273993.0 314860.0 405116.0 344335.0 331278.0 273555.0 328645.0 267759.0 295117.0 True False 348658.2172261752 362555.8790248558 310684.75067413074 311722.7651798075 296530.02890474675 310563.1342905875 297900.86505374586 277860.4667608018 281912.19409916754 284785.0436566239 1.2242855620134516 1.273086094584388 1.0909447584920755 1.094589663759391 1.041241580306739 1.090517712247014 1.0460551622680585 0.9756848997162528 0.9899122175779699 1.0 18.119513855260045 -4.555858216503569 0.4062372216282303 0.9903960850220656 1.523872067885633 0.8338835811364576 0.03791235924097263 2.580416537160381 0.2920417516251291 0.031021766857438602 0.6958088887073398 2.7806209049112406e-05 4.555858216503569 0.5334759828635675 PVSVAGS(ph)PLSPGPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PVSVAGSPLSPGPVR 15 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 PVS(0.011)VAGS(0.66)PLS(0.329)PGPVR 70.26 0.02408 10669000.0 41499.0 39207.0 33470.0 37973.0 44639.0 30486.0 37146.0 39504.0 40737.0 32264.0 True False 48523.96105738867 43099.21184996384 34268.05173568185 35845.49592012703 35892.308393742715 28887.26049246422 33627.261966249054 38467.06185794784 41332.701558167646 38113.20779831653 1.2731534252945245 1.1308208975227623 0.8991122425857705 0.9405006293306631 0.941728877392684 0.7579330673326368 0.8822994418154008 1.009284289622217 1.084471865419665 1.0 15.218003417244674 -5.044875205624753 2.815855522704695 0.9311443139908304 1.2698978623349635 0.6308591293115613 0.08327501259468406 0.19175881336596123 2.800841428337156 0.02386299995406424 0.11220936859500254 9.018302409980005e-06 5.044875205624753 0.33875354834413307 PVSVAGS(ph)PLSPGPVR ddPTM_PC-9_Lapatinib_30min_R1 1 PVSVAGSPLSPGPVR 15 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 PVS(0.013)VAGS(0.703)PLS(0.284)PGPVR 76.156 0.014236000000000002 10919000.0 57146.0 45279.0 87021.0 45354.0 64718.0 76642.0 56092.0 61080.0 75901.0 46314.0 True False 56331.0875607071 45174.15925743347 79866.4692907741 48689.4844565088 60911.414480483545 73364.20032122808 58996.16929973614 63917.9997835027 67352.23010703671 54319.31319047413 1.037036078920559 0.8316408401377868 1.4703144167290414 0.8963567761944269 1.1213583328436756 1.3506098662177823 1.0860993233265361 1.1767085412028346 1.2399315483033047 1.0 15.729177617914106 -5.21538539206431 24.99973869789018 1.1662600405914465 0.9343384341045682 0.24949128774193086 0.16186304788371464 571.2051050139703 310068.49052747333 0.03896777011553706 0.10309848014820118 6.089962353297113e-06 5.21538539206431 -0.23192160648687832 PVSVAGSPLS(ph)PGPVR ddPTM_PC-9_AZD4547_30min_R2 2 PVSVAGSPLSPGPVR 15 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 PVS(0.001)VAGS(0.076)PLS(0.923)PGPVR;PVSVAGS(0.005)PLS(0.995)PGPVR 161.94 0.00012964 65182000.0 81855.0 110802.0 117877.0 124545.0 114380.0 123381.0 131293.0 151032.0 108030.0 125363.0 True False 107883.1873102314 146616.5796487943 116313.8739605365 95833.07445106853 98500.31134251501 115665.96656556443 142977.82265175704 127693.47477009357 113740.24525238392 120974.07952752725 0.8917876269989137 1.2119668958955143 0.961477652194656 0.7921785792903019 0.8142265824812628 0.9561218983215741 1.181888080572028 1.055544090674708 0.9402034361129625 1.0 16.884338436456865 -7.029250855748726 24.34848641157278 1.051890087717568 0.9375441687139082 0.15725032090077828 0.12099256457809575 1039.9794296798996 865678.2867354037 0.05040069651522386 0.03912015140949409 9.348655242166958e-08 7.029250855748726 -0.11434591900365987 PVSVAGSPLS(ph)PGPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 PVSVAGSPLSPGPVR 15 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 PVS(0.013)VAGS(0.394)PLS(0.594)PGPVR;PVS(0.015)VAGS(0.359)PLS(0.626)PGPVR;PVSVAGS(0.016)PLS(0.984)PGPVR;PVSVAGSPLS(1)PGPVR 203.52 9.6978e-13 134236000.0 175585.0 236012.0 233178.0 241894.0 238185.0 158599.0 219916.0 171058.0 140047.5 181343.0 True False 205308.07253817155 259441.71161103027 238737.84785248988 228341.463410929 191514.35907532944 150281.78924241726 199083.96442603852 166567.9087509322 142095.42974366035 214219.05038960226 0.9584024957853924 1.2111047600070168 1.1144566620862852 1.0659251032792936 0.8940118011307604 0.7015332621869919 0.9293476190094326 0.7775588046347583 0.6633183626070138 1.0 17.708727258355538 -6.323233151140586 2.9405143581920634 0.8067277847027209 1.103727581200614 0.5823745346248026 0.10910773339601873 0.17610507289240285 3.0082923865531006 0.03446277046103063 0.04126998355200325 4.7508011055031743e-07 6.323233151140586 0.2969997964978931 PVSVAGSPLS(ph)PGPVR ddPTM_PC-9_Lapatinib_30min_R1 5 PVSVAGSPLSPGPVR 15 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 PVSVAGS(0.014)PLS(0.986)PGPVR;PVSVAGS(0.004)PLS(0.996)PGPVR;PVS(0.001)VAGS(0.16)PLS(0.839)PGPVR;PVSVAGS(0.005)PLS(0.995)PGPVR;PVS(0.144)VAGSPLS(0.855)PGPVR 173.51 2.5759000000000002e-05 161659000.0 259565.0 397409.0 410084.0 337032.0 358471.0 314862.0 278266.0 309006.0 297047.0 240775.0 True False 255863.55550160928 396488.8238772367 376368.4764900171 361818.4575857926 337386.44056110195 301396.0862391708 292673.25191400514 323363.546841864 263590.43881641777 282392.6379374785 0.9060560408740446 1.404033854328097 1.332784307830804 1.2812602347866409 1.1947423382751183 1.067294418298184 1.0364053895017007 1.145084904491938 0.9334182390221394 1.0 18.10734295203479 -6.70762197015144 2.8284294567356336 1.0413573810619623 1.2501865874575093 0.3347433898795634 0.13199696395870136 0.30471420986246756 4.97218612561379 0.04741406331706479 0.04543596135315815 1.9605504841092438e-07 6.70762197015144 0.20882920639554703 PVTATLPTSS(ph)NS(ph)PIMVVS(ph)S(ph)NGAIMTTK ddPTM_PC-9_AZD4547_30min_R2 1 PVTATLPTSSNSPIMVVSSNGAIMTTK 27 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;Q7Z589-2;H0YDI4;E9PPE6 E9PMC9 C11orf30;EMSY Protein EMSY 4 PVT(0.182)AT(0.197)LPT(0.224)S(0.234)S(0.245)NS(0.918)PIMVVS(0.546)S(0.545)NGAIMT(0.462)T(0.447)K 47.479 0.031181 0.0 12868.0 13518.0 20231.0 21652.0 21217.0 17813.0 18155.0 18647.0 17932.0 19661.0 True False 16959.75632897267 17887.429141102166 19962.723721299437 16660.465920065322 18271.38578207852 16699.15029406793 19770.75982910474 15765.534615432067 18879.848911096447 18972.67437434265 0.89390435920346 0.94279956468825 1.0521829093475437 0.878129545226149 0.9630369141204203 0.8801684973126784 1.042064995109038 0.8309600588914497 0.995107412828856 1.0 14.211635433873788 -8.480367228476354 24.995313779905132 1.0000010406696755 0.9385684497371641 0.1198706432354264 0.0669882458403111 852.8426143306239 501442.912656181 0.060496606313163434 0.015620156567411423 3.3085124369116053e-09 8.480367228476354 -0.06143259093251141 PVVDGEEGEPHS(ph)ISPR ddPTM_PC-9_Lapatinib_30min_R1 2 PVVDGEEGEPHSISPR 16 0 P36507;G5E9C7 P36507 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 1 PVVDGEEGEPHS(0.5)IS(0.5)PR;PVVDGEEGEPHS(0.672)IS(0.328)PR 100.02 0.0010389000000000002 6573900.0 9229.1 23065.7 19015.0 19398.0 23132.6 22372.2 26491.0 29468.0 26801.0 20325.0 True False 9097.491341590347 23012.29278880239 17451.66010002264 20824.593629831044 21771.985948441452 21415.393158145394 27862.57435854151 30837.190858222973 23782.38915295831 23838.14916863986 0.3816358089393324 0.9653556836986356 0.732089558487245 0.8735826545303575 0.9133253506561434 0.8983664380420227 1.168822888112302 1.2936067578094805 0.9976608915697657 1.0 14.540984606587745 -4.482822705969127 0.39449564264759046 1.128597898791187 6.337516192003059e-16 0.5959766603371452 0.14821686732418762 5.339607102846018 0.5491437017351869 0.12392030866425792 2.9904204222974706 3.289859068937207e-05 4.482822705969127 -1.1285978987911864 PVVEGSLGS(ph)PPFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PVVEGSLGSPPFEK 14 0 Q92830;K7ERS6;K7ERQ8 Q92830 KAT2A Histone acetyltransferase KAT2A 1 PVVEGS(0.029)LGS(0.971)PPFEK 78.964 0.013331 87306000.0 33537.0 37852.0 31560.0 31417.0 30462.0 28608.0 33416.0 26587.0 29077.0 26596.0 True False 39214.15171405681 41609.69640484689 32312.51009196653 29656.807345288256 24493.18977329668 27107.746118494273 30250.594569110515 25889.119421255044 29502.196116720435 31417.64426617982 1.2481569713445926 1.3244053580948625 1.0284829065542005 0.9439538844487123 0.7795998186809596 0.8628191817575251 0.9628536854265168 0.8240312100396378 0.9390327252663782 1.0 14.93928738917861 -5.4581198468610435 2.4126686459304394 0.8892038342455436 1.292837525414674 0.835861987153789 0.06699870422763088 0.10342750669744624 1.1677831105617489 0.0185243572766038 0.0469820822692581 3.4824120197024376e-06 5.4581198468610435 0.4036336911691304 PWS(ph)QQPDPY(ph)ANLMT(ph)RK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PWSQQPDPYANLMTRK 16 1 C9JE40 C9JE40 PATL2 Protein PAT1 homolog 2 3 PWS(1)QQPDPY(1)ANLMT(1)RK 57.159 0.035282 0.0 13662.0 19275.0 18003.0 23401.0 22179.0 23835.0 20558.0 20558.0 22003.0 22527.0 True False 15974.706763200174 21188.494615962783 18432.259796757702 22089.917837065615 17833.184163283673 22585.05064088055 18610.59741296905 20018.37428300151 22324.752249413617 26610.966776366113 0.600305389031853 0.7962316737316298 0.6926565258473761 0.8301057989627134 0.6701441669951572 0.8487121430304034 0.6993581845172797 0.752260316253536 0.8389305220297674 1.0 14.699733303969442 -14.52287874466507 0.16556160084830235 1.9753739488194062 0.6857472814772382 0.5720374783335045 0.07109913533632524 94.52654661668211 0.8791378303952929 30.135141374613276 0.25743835981543034 3.000000004250121e-15 14.52287874466507 -1.289626667342168 PWS(ph)ST(ph)DSDGS(ph)VRS(ph)MR ddPTM_PC-9_AZD4547_30min_R2 2 PWSSTDSDGSVRSMR 15 1 Q9Y2K5-2;H7C0E9;A0A0U1RRA6;B5MCU0;B5MCG9;Q9Y2K5;H0YIX9 Q9Y2K5-2 R3HDM2 R3H domain-containing protein 2 4 PWS(0.728)S(0.275)T(0.952)DS(0.058)DGS(0.995)VRS(0.992)MR;PWS(0.927)S(0.126)T(0.946)DS(0.108)DGS(0.972)VRS(0.921)MR 56.872 0.016778 35209000.0 68704.0 86411.0 78171.0 65007.0 80258.0 110466.0 102796.0 110449.0 90152.0 84480.0 True False 90550.44286802449 114341.665890796 77134.40146397603 50020.64049813816 69115.56205392188 103558.54355720586 111944.64485776087 93381.64491552845 94917.25067104418 81522.38091371086 1.1107433548079217 1.402580059724009 0.9461745424930684 0.6135816929964741 0.8478108867683679 1.2703081337481992 1.3731768331968999 1.1454724931840532 1.1643091088263406 1.0 16.314908566507583 -6.773880213013692 24.99027936656694 1.2111530892198838 0.984722650967044 0.1957291874625865 0.20719736063112107 405.1316559746312 813795.3296114842 0.08199709166555168 0.07280997842662774 1.6831382397858802e-07 6.773880213013692 -0.22643043825283982 PWS(ph)ST(ph)DSDGS(ph)VRS(ph)MR ddPTM_PC-9_Lapatinib_30min_R1 1 PWSSTDSDGSVRSMR 15 1 Q9Y2K5-2;H7C0E9;A0A0U1RRA6;B5MCU0;B5MCG9;Q9Y2K5;H0YIX9 Q9Y2K5-2 R3HDM2 R3H domain-containing protein 2 4 PWS(0.743)S(0.263)T(0.983)DS(0.406)DGS(0.847)VRS(0.757)MR 46.156000000000006 0.032296 19536000.0 9793.2 16189.0 13915.0 10630.0 10904.0 12007.0 10645.0 11523.0 11717.0 10726.0 True False 9653.547172147075 16151.515365149195 12770.962413453331 11411.76566064048 10262.648158088828 11493.48859968406 11196.146013614976 12058.400646779672 10397.308074520082 12579.974808503384 0.767374125870411 1.2839068130908848 1.0151818749923767 0.9071374016525646 0.8157924252083424 0.913633673726841 0.8899974907777228 0.9585393317821943 0.8264967325285948 1.0 13.618841412761594 -5.718473880748557 4.630763729283696 0.8958162393612479 1.0526927527500745 0.1499912268298128 0.12715196957040165 0.2866634401074871 13.442216696966804 0.03323791658880815 0.057359712935555945 1.912168322389335e-06 5.718473880748557 0.15687651338882658 PWSQQPDPY(ph)ANLMT(ph)RK ddPTM_PC-9_AZD4547_30min_R2 1 PWSQQPDPYANLMTRK 16 1 C9JE40 C9JE40 PATL2 Protein PAT1 homolog 2 2 PWS(0.01)QQPDPY(0.99)ANLMT(1)RK 68.044 0.022838 0.0 2308.4 3089.2 3320.2 3748.8 3319.5 4046.2 3121.5 3470.7 2494.4 3864.1 True False 3042.4231822972106 4087.7234874014516 3276.17197861986 2884.5720783826405 2858.6447237408483 3793.190474364655 3399.3074528532343 2934.3830637518113 2626.2488915814706 3728.819035140501 0.8159213825142289 1.0962515072141137 0.8786084676529267 0.773588648630665 0.7666354137331138 1.017263224258811 0.9116311145212627 0.786947029635415 0.7043111684508214 1.0 11.86450306744259 -5.505526129741013 24.661175567470494 0.8467616751092963 0.9639223447381295 0.11277488098196842 0.11481312944766152 1157.97009505722 1645679.813376601 0.030361023429554136 0.060974756860222065 3.122294544747747e-06 5.505526129741013 0.1171606696288332 PWSS(ph)T(ph)DS(ph)DGS(ph)VRSMR ddPTM_PC-9_AZD4547_30min_R2 1 PWSSTDSDGSVRSMR 15 1 Q9Y2K5-2;H7C0E9;A0A0U1RRA6;B5MCU0;B5MCG9;Q9Y2K5;H0YIX9 Q9Y2K5-2 R3HDM2 R3H domain-containing protein 2 4 PWS(0.458)S(0.547)T(0.996)DS(0.933)DGS(0.996)VRS(0.07)MR 60.401 0.032205000000000004 0.0 12299.0 11639.0 12869.0 10180.0 11808.0 15662.0 13946.0 18402.0 16168.0 11945.0 True False 16209.826164907885 15401.079136949857 12698.348651544778 7833.158279432152 10168.66302091639 14682.652664104398 15187.166983018167 15558.393735892141 17022.607472373813 11526.809185775037 1.4062717534104796 1.3361094895156211 1.101636059631794 0.6795599851777601 0.8821750110572922 1.273782920101073 1.3175516952046271 1.3497572038489531 1.476784008308302 1.0 13.49270558560546 -6.934209304501493 10.837908378135017 1.312397014791209 1.0742097226859468 0.16649641856038777 0.2232207766439003 0.888802555598833 141.93489081487422 0.08683228598318836 0.07657840220143118 1.1635651240255834e-07 6.934209304501493 -0.23818729210526213 PWSS(ph)T(ph)DS(ph)DGS(ph)VRSMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PWSSTDSDGSVRSMR 15 1 Q9Y2K5-2;H7C0E9;A0A0U1RRA6;B5MCU0;B5MCG9;Q9Y2K5;H0YIX9 Q9Y2K5-2 R3HDM2 R3H domain-containing protein 2 4 PWS(0.079)S(0.926)T(0.908)DS(0.699)DGS(0.973)VRS(0.414)MR 47.638999999999996 0.029929 26556000.0 47511.0 69519.0 63539.0 52054.0 60869.0 39417.0 54230.0 36383.0 38067.0 39997.0 True False 55553.67391497607 76420.38688493487 65054.01073299938 49137.58314134499 48942.156401772554 37349.90313033725 49092.941808800075 35427.98480097498 38623.657859311395 47248.139483922234 1.17578542820464 1.6174263731789793 1.3768586751471175 1.039989800192359 1.03585362167386 0.7905052672613025 1.0390449728820665 0.7498281453607404 0.8174641008341587 1.0 15.527969900202399 -5.914656905391887 1.9707534314025075 0.8889149932317152 1.4264230226054306 0.7105713900969376 0.1378994147156295 0.16416050612169933 1.2950331889758013 0.0425769640194512 0.0731623880364567 1.2171471727115106e-06 5.914656905391887 0.5375080293737154 PWSS(ph)T(ph)DSDGS(ph)VRS(ph)MR ddPTM_PC-9_AZD4547_30min_R2 2 PWSSTDSDGSVRSMR 15 1 Q9Y2K5-2;H7C0E9;A0A0U1RRA6;B5MCU0;B5MCG9;Q9Y2K5;H0YIX9 Q9Y2K5-2 R3HDM2 R3H domain-containing protein 2 4 PWS(0.457)S(0.552)T(0.919)DS(0.139)DGS(0.99)VRS(0.942)MR;PWS(0.423)S(0.582)T(0.88)DS(0.578)DGS(0.951)VRS(0.586)MR 46.41 0.031889999999999995 17190000.0 58870.5 68621.0 62911.5 42954.9 54857.9 64263.0 75104.2 76237.0 67258.1 57589.7 True False 77590.09441753064 90801.39629320706 62077.25240435616 33052.311451589405 47241.82750128126 60244.62445111361 81788.32830388575 64456.32340197854 70813.22585586751 55573.5021319404 1.3961706828070566 1.6338973217421136 1.1170296998194358 0.5947494792233522 0.8500782871146323 1.084053049384637 1.4717144892129914 1.1598391486818467 1.2742264413667068 1.0 15.762109538484244 PWSS(ph)T(ph)DSDGS(ph)VRS(ph)MR ddPTM_PC-9_Lapatinib_30min_R1 3 PWSSTDSDGSVRSMR 15 1 Q9Y2K5-2;H7C0E9;A0A0U1RRA6;B5MCU0;B5MCG9;Q9Y2K5;H0YIX9 Q9Y2K5-2 R3HDM2 R3H domain-containing protein 2 4 PWS(0.471)S(0.561)T(0.961)DS(0.462)DGS(0.977)VRS(0.568)MR;PWS(0.475)S(0.548)T(0.8)DS(0.414)DGS(0.967)VRS(0.797)MR;PWS(0.191)S(0.812)T(0.965)DS(0.336)DGS(0.961)VRS(0.734)MR 54.812 0.018859 74540000.0 47618.9 73593.0 62552.0 57518.0 82360.0 64789.0 67210.0 77908.0 67524.0 69627.0 True False 46939.84575376327 73422.59993004041 57409.21601770263 61748.06559442324 77515.74672599 62018.12550053559 70689.8049389443 81527.89009713723 59918.73606075739 81661.9341778543 0.574806930871015 0.8991043460975444 0.703010730711682 0.7561425799680428 0.9492274155197674 0.759449627600838 0.8656396110455402 0.9983585487893891 0.7337413283679803 1.0 16.31737611801323 -1.9690252705328062 0.15380100504290928 0.9891928128064945 7.545344426999915e-15 0.354181977591968 0.10724352144524167 69.26516152680937 0.7878015335596131 0.3509454315636994 14.975911698244806 0.010739269213444421 1.9690252705328062 -0.989192812806487 PWTPGQPGGLVGCPGS(ph)GGSPMRR ddPTM_PC-9_AZD4547_30min_R2 1 PWTPGQPGGLVGCPGSGGSPMRR 23 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 PWTPGQPGGLVGCPGS(0.559)GGS(0.441)PMRR 59.893 0.0020856 6202500.0 18370.0 15886.0 16900.0 21894.0 20810.0 17900.0 14815.0 18128.0 21024.0 26191.0 True False 24211.277880263275 21020.838832338282 16675.89495773616 16846.676558928066 17920.890706747123 16780.71017031471 16133.50629954211 15326.734139998513 22135.28571865333 25274.061061919947 0.9579496473062672 0.8317159154137705 0.65980274863154 0.6665599373861886 0.7090625706269367 0.6639498942889696 0.6383424594890381 0.6064215047375617 0.875810407532972 1.0 14.625369876169396 -8.498171652892132 5.14337651931763 0.9996045751388919 0.7130256753819936 0.4650093579761254 0.09929899870373132 0.1438656613226383 11.652984048849302 0.10307463623939758 0.026797921620605913 3.1756186739280767e-09 8.498171652892132 -0.2865788997568983 PWTPGQPGGLVGCPGSGGS(ph)PMRR ddPTM_PC-9_AZD4547_30min_R2 1 PWTPGQPGGLVGCPGSGGSPMRR 23 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 PWTPGQPGGLVGCPGS(0.063)GGS(0.937)PMRR 98.32600000000001 0.00051021 0.0 15805.0 12962.0 14855.0 20604.0 18972.0 20903.0 19567.0 14726.0 16237.0 20244.0 True False 20830.661235577638 17151.71301427477 14658.012993915425 15854.066128626735 16338.065280557728 19595.932105591517 21308.42509369829 12450.435069815658 17095.254671507526 19535.26372179405 1.0663107256821114 0.8779872777012921 0.7503360693084764 0.8115614078421437 0.8363370729585061 1.0031055830451772 1.090767209347988 0.6373313023629994 0.875097204469045 1.0 14.253793111270488 -10.965829859599246 5.797893416878393 1.0000718529592936 0.8780566906094265 0.06376697865261616 0.13294914597622812 0.00012757876008378177 1.2257608562809042e-05 0.13299770769691177 0.03223771641436694 1.0818576998362002e-11 10.965829859599246 -0.12201516234986709 PY(ph)LRSEFSPS(ph)VDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PYLRSEFSPSVDAR 14 1 P00540 P00540 MOS Proto-oncogene serine/threonine-protein kinase mos 2 PY(1)LRS(0.031)EFS(0.05)PS(0.919)VDAR 83.243 0.023941 0.0 661.24 726.75 861.25 835.82 1028.9 2230.3 1222.0 868.79 547.13 1091.9 True False 773.1748719146897 798.8969370765733 881.7854663088133 788.9917151650017 827.2944310204504 2113.339141781243 1106.243313486146 845.985183059095 555.1307411817336 1289.8528265243567 0.599428753432351 0.6193706139554577 0.6836326193003557 0.6116912712367522 0.6413866869212371 1.6384343223682785 0.8576508038262274 0.6558772951939722 0.4303830094147961 1.0 10.332990746778579 -6.579855435271851 24.999970928807542 0.9189097757685102 0.6311319635736016 0.19511012729418298 0.28985618196384816 152.88044148808717 67078.86709366887 0.10203390112024678 0.10203390454941566 2.631143681747489e-07 6.579855435271851 -0.2877778121949086 PY(ph)QYPALTPEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PYQYPALTPEQK 12 0 P04075;J3KPS3;H3BQN4;H3BUH7;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 PY(0.814)QY(0.133)PALT(0.053)PEQK 101.46 0.0039346 11755000.0 52388.0 58842.0 51191.0 65061.0 56512.0 44567.0 58822.0 39050.0 42596.0 45040.0 True False 61256.25368983534 64683.44488676955 52411.587582948625 61415.84310060794 45438.879274786355 42229.828064280395 53249.95432559909 38024.97887689509 43218.885916285195 53205.39546355615 1.1513165752483459 1.2157309296023457 0.9850803123688601 1.154316071998293 0.8540276578887644 0.7937132634077753 1.0008374876580601 0.7146827600020542 0.8123026911037364 1.0 15.69928493380639 -6.265857857647379 24.547361084900682 0.8517962403311242 1.1228673563812324 0.6311547697954885 0.0986526244539169 185.743731847468 1031918.8259593878 0.02981800591543041 0.034991817416869395 5.421783135416322e-07 6.265857857647379 0.27107111605010814 PYGCLLCGKAFS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 PYGCLLCGKAFSK 13 1 Q8TC21-2;Q8TC21 Q8TC21-2 ZNF596 Zinc finger protein 596 1 PYGCLLCGKAFS(1)K 51.888000000000005 0.045263 12923000.0 50209.0 31962.0 112340.0 42064.0 92045.0 99689.0 59939.0 75857.0 121890.0 64989.0 True False 49493.01045279707 31887.99395273942 103103.83884494036 45157.52688139051 86631.09406743258 95425.53385640906 63042.348136220564 79381.59314959355 108161.46464139731 76222.26205760075 0.6493248706709265 0.4183553871524022 1.3526735636240415 0.59244537832353 1.136558949168498 1.2519378365377887 0.827085767785005 1.0414489285243897 1.4190272201533494 1.0 16.217924803375958 -5.2493789075190795 24.99538435504079 1.0611789242741825 0.5338400763692066 0.4566513214366952 0.23673024354185335 669.8807989144482 1388325.162091543 0.058632890365990266 0.1526525027038464 5.631461151388132e-06 5.2493789075190795 -0.5273388479049759 PYHPPPLFPPS(ph)PQPPDSTPR ddPTM_PC-9_AZD4547_30min_R2 1 PYHPPPLFPPSPQPPDSTPR 20 0 P54259 P54259 ATN1 Atrophin-1 1 PY(0.001)HPPPLFPPS(0.999)PQPPDSTPR 131.64 2.3104e-05 8107000.0 21328.0 21443.0 21321.0 27570.0 23318.0 26246.0 22082.0 26787.0 26387.0 27610.0 True False 28109.8603500411 28374.03040928051 21038.269609106068 21214.16245225388 20080.698197978363 24604.83347095418 24047.255221497726 22647.68465402363 27781.762949871827 26643.38230382995 1.0550409865192059 1.0649560211881126 0.7896245817889963 0.7962263278114046 0.7536842721012862 0.923487610933589 0.9025601534847536 0.8500303901268592 1.0427265815225808 1.0 14.701489619737197 -10.17610812140081 13.73839248835123 0.9999999805391525 0.9004581932207243 0.054741999663649676 0.10907078456326304 0.0 0.0 0.11311507773946834 0.027434436080575355 6.666407825128201e-11 10.17610812140081 -0.09954178731842822 PYHPPPLFPPS(ph)PQPPDSTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 PYHPPPLFPPSPQPPDSTPR 20 0 P54259 P54259 ATN1 Atrophin-1 1 PYHPPPLFPPS(1)PQPPDSTPR;PY(0.001)HPPPLFPPS(0.999)PQPPDSTPR;PYHPPPLFPPS(0.999)PQPPDS(0.001)T(0.001)PR 166.01 2.5354e-08 16520300.0 94748.0 140419.0 108143.0 89829.0 100892.0 76815.0 101644.0 67296.0 71901.0 85862.0 True False 110786.96504169866 154358.8703231585 110721.53925461158 84796.17235954721 81122.93685928186 72786.68617492092 92015.54448116664 65529.55130600592 72952.41610167197 101428.100916782 1.0922709194032456 1.5218550769259127 1.091625873439694 0.8360224789096596 0.799807313023047 0.7176185447328812 0.9071997173314128 0.6460689958078826 0.7192525093369019 1.0 16.630097884537093 -5.632178224259032 3.0073721537418963 0.7861491342137131 1.3104790081440176 0.6902151187370305 0.13678654572110693 0.12278595664190073 2.2104525299653264 0.03646403354093037 0.07053974104521661 2.3325006623377016e-06 5.632178224259032 0.5243298739303045 PYHPPPLFPPS(ph)PQPPDSTPR ddPTM_PC-9_Lapatinib_30min_R1 2 PYHPPPLFPPSPQPPDSTPR 20 0 P54259 P54259 ATN1 Atrophin-1 1 PY(0.001)HPPPLFPPS(0.978)PQPPDS(0.01)T(0.01)PR;PYHPPPLFPPS(1)PQPPDSTPR 121.65 5.4886e-06 13663100.0 109170.0 129316.0 119459.0 110257.0 123080.0 125721.0 118609.0 126806.0 112906.0 109354.0 True False 107613.21578067393 129016.57674715143 109637.54214507525 118365.66758656963 115840.67638459036 120344.20589996505 124749.99366170577 132697.86968806226 100189.33732711141 128255.69319495399 0.8390521551125014 1.0059325518676263 0.8548356756251094 0.9228882136767909 0.9032010470561156 0.938314728197187 0.9726663242315535 1.0346353162378217 0.7811687327970654 1.0 16.96866334207676 -6.88607393516492 4.5350392982962715 0.9506664026780555 0.9090641009639273 0.06570845671672843 0.07494686376122492 0.6678767753127326 23.471445580234818 0.025850298304552394 0.02273842501535121 1.299948253392724e-07 6.88607393516492 -0.041602301714128154 PYQYPALT(ph)PEQK ddPTM_PC-9_AZD4547_30min_R2 4 PYQYPALTPEQK 12 0 P04075;J3KPS3;H3BQN4;H3BUH7;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 PYQYPALT(1)PEQK;PYQYPALT(1)PEQK;PY(0.001)QY(0.006)PALT(0.993)PEQK;PYQYPALT(1)PEQK 123.72 0.00083993 52669000.0 183588.0 188712.0 196619.0 189360.0 185746.0 191514.0 180474.0 211755.0 170479.0 201567.0 True False 241965.1651323775 249709.46353570608 194011.70359142742 145705.97758283615 159958.37410934435 179538.59930489707 196535.83637553576 179033.1303958181 179490.17190022356 194510.20068221953 1.2439715978067771 1.2837859539493675 0.9974371673616926 0.7490917035291268 0.8223649636281847 0.9230292225044677 1.0104140332291651 0.9204305469218704 0.9227802514761944 1.0 17.569486290767856 -5.358290483384204 3.9731809902068975 0.9033721393650429 1.2652148168281374 0.7819896711068179 0.07401672962776104 0.10095899452182046 2.8299428251978074 0.021405296330357836 0.04890817408397162 4.38237479016431e-06 5.358290483384204 0.3618426774630945 PYQYPALT(ph)PEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 PYQYPALTPEQK 12 0 P04075;J3KPS3;H3BQN4;H3BUH7;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 PYQYPALT(1)PEQK;PYQYPALT(0.999)PEQK;PYQY(0.004)PALT(0.996)PEQK 110.31 0.002955 38855000.0 207797.0 255874.0 181962.0 218599.0 198407.0 152823.0 217577.0 153584.0 151268.0 176320.0 True False 242972.92792217128 281275.4797076452 186300.66417472824 206351.60673751996 159530.57262656649 144808.6928504842 196966.5314389321 149552.58273569902 153480.00832906 208285.4202516482 1.166538337770421 1.3504328789207194 0.8944488958931537 0.9907155598707206 0.7659228976940554 0.695241619291105 0.9456568357063075 0.718017528807399 0.7368735082063214 1.0 17.66820233029732 -5.474726476956022 1.650876199085785 0.8078235788607246 1.273908692781645 0.6420018823365546 0.12070042900398334 0.23649319241600125 1.208654610076326 0.03496693439909581 0.11262855369978957 3.3517647021685387e-06 5.474726476956022 0.46608511392092034 PYQYPALT(ph)PEQK ddPTM_PC-9_Lapatinib_30min_R1 4 PYQYPALTPEQK 12 0 P04075;J3KPS3;H3BQN4;H3BUH7;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 PYQYPALT(1)PEQK;PYQY(0.001)PALT(0.999)PEQK;PYQY(0.07)PALT(0.93)PEQK;PYQYPALT(1)PEQK 164.88 0.00016876 56603000.0 179259.0 221392.0 196991.0 200525.0 200403.0 182570.0 193371.0 203383.0 175528.0 181197.0 True False 176702.73378792556 220879.38042628413 180795.16038724978 215272.27743179 188615.68954745727 174761.90669145662 203382.80420843058 212832.91666614515 155758.18824821708 212516.66002017361 0.8314770887663662 1.0393508932679285 0.850734057132685 1.0129665947665223 0.8875336622058361 0.8223445007787482 0.9570205187166221 1.0014881498981845 0.7329222482295336 1.0 17.697216418681734 PYQYPALT(ph)PEQKK ddPTM_PC-9_Lapatinib_30min_R1 1 PYQYPALTPEQKK 13 1 P04075;J3KPS3;H3BQN4;H3BUH7;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 PYQYPALT(1)PEQKK 63.614 0.037993 12450000.0 146470.0 59350.0 63568.0 61280.0 52070.0 57518.0 35271.0 32612.0 56796.0 41074.0 True False 144381.31094069147 59212.57872145312 58341.68441957605 65786.73562408725 49007.34497355876 55058.089221006754 37097.15979767154 34127.272575959236 50399.03639160554 48173.58617233522 2.997105310453423 1.22915031713909 1.2110720636588208 1.3656183990276973 1.017307384969034 1.1429103289932174 0.770072621642925 0.7084229198522405 1.046196482265386 1.0 15.555954705601492 -2.9188812905920134 1.2434544891943122 0.9978326305421097 199.9998978820234 0.9036463439773175 0.19036355004966068 45.224798844949404 0.9211880972450903 0.061097172400545456 24872.674317217545 0.00120536536812472 2.9188812905920134 199.00206525148127 up PYQYPALTPEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 PYQYPALTPEQK 12 0 P04075;J3KPS3;H3BQN4;H3BUH7;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ; 155.97 0.0015955 13092800.0 82005.0 89471.0 75562.0 84384.0 80091.0 65696.0 93091.0 70576.0 66723.0 82083.0 False True 95886.82682742128 98353.08958676028 77363.68465048092 79656.23805661911 64397.743488054155 62250.78610880172 84272.7465595245 68723.45478145329 67698.69764748572 96963.99813132957 0.9888910180616793 1.0143258475537416 0.7978598876017707 0.8215032341048009 0.6641407607886881 0.6419989615577554 0.8691137760778403 0.7087522802883308 0.6981838512454235 1.0 16.565161566451508 -5.349414874675823 2.5080609080137224 0.7542843379770765 1.0112029281452641 0.42906540633936663 0.1027120827243566 0.24950216239150302 2.9935761208489198 0.027463621522605654 0.0786549963509914 4.47285814930429e-06 5.349414874675823 0.25691859016818763 PYQYPALTPEQK ddPTM_PC-9_Lapatinib_30min_R1 2 PYQYPALTPEQK 12 0 P04075;J3KPS3;H3BQN4;H3BUH7;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ; 155.97 0.0005139999999999999 35360000.0 73524.0 70120.0 69105.0 65232.0 68732.0 52159.0 68577.0 60310.0 57073.0 75356.0 False True 72475.53427734958 69957.64144816012 63423.45365301424 70029.37888757294 64689.318892311196 49928.28115856757 72127.58151016204 63112.22277247954 50644.83773466623 88381.18419444161 0.8200335279271767 0.7915445135273469 0.7176126257086631 0.7923561957883017 0.731935416818952 0.5649198029381871 0.8160965726763618 0.7140911648528097 0.5730273722430089 1.0 16.431451641035892 -10.725168864321002 3.789044713450782 1.0002533507096243 0.7262767020629802 0.47547758855713307 0.08675328192885144 130178725.13333549 244291935.9294944 411591.4218413418 0.021841863479067438 1.882916823004945e-11 10.725168864321002 -0.27397664864664406 PYS(ph)NVSNLK ddPTM_PC-9_AZD4547_30min_R2 1 PYSNVSNLK 9 0 O95248;O95248-5;O95248-4 O95248 SBF1 Myotubularin-related protein 5 1 PY(0.042)S(0.958)NVSNLK 67.385 0.026008999999999997 19306000.0 9108.2 7575.0 12898.0 21941.0 13713.0 8359.2 9370.6 10522.0 8980.5 12863.0 True False 12004.418137670868 10023.470612801366 12726.96409259651 16882.84143507081 11809.186653609968 7836.497902552775 10204.565246742442 8896.066671506205 9455.190895945878 12412.670285192484 0.9671100465780812 0.8075192833212304 1.0253204024744746 1.360129693866996 0.9513816432953647 0.6313305455234086 0.8221087817756532 0.7166924172729087 0.7617370540507559 1.0 13.599525889280347 -6.550145607102474 11.468636434114032 0.7730411331066936 1.0390074252057024 0.3764903445858939 0.1547147579224544 0.6960783171478885 289.3084701664207 0.053276910519817214 0.053405167876703734 2.81743816267303e-07 6.550145607102474 0.2659662920990088 PYSCGECGKGFSCSSHLSSHQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 PYSCGECGKGFSCSSHLSSHQK 22 1 A0A087WVZ7;Q9UJW7-2;Q9UJW7 A0A087WVZ7 ZNF229 Zinc finger protein 229 0 43.955 0.034012 4729000.0 4283.1 1894.0 33592.0 15423.0 35096.0 24467.0 10865.0 15117.0 20499.0 10172.0 False True 5008.144234918948 2082.023802990066 34392.960678369425 14558.89931204065 28219.19073874402 23183.90744830813 9835.78854421193 14720.194767785479 20798.759094702073 12016.103078492311 0.41678605802600455 0.17326946926052023 2.862239151387572 1.2116157140911767 2.3484477916350186 1.929403176459524 0.8185506132863541 1.225038989065701 1.7309071800432443 1.0 13.552681473528905 -5.221367507100163 24.9835451017623 1.6397025237776843 0.2950266972936136 0.4488877079829795 0.5964499632660405 464.80864442790835 289792.1003415386 0.15089619181455954 0.3992224381548752 6.006652296093509e-06 5.221367507100163 -1.3446758264840708 QAAS(ph)PLEPK ddPTM_PC-9_AZD4547_30min_R2 4 QAASPLEPK 9 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;Q14980-4;Q14980-3;F5H6Y5;F5H4J1 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 QAAS(1)PLEPK;QAAS(1)PLEPK;QAAS(1)PLEPK;QAAS(1)PLEPK 111.52 0.0022291999999999998 78987400.0 617382.0 643210.0 694019.0 822000.0 818200.0 796440.0 670207.0 795880.0 717198.0 749173.0 True False 813696.6336566538 851115.0538429003 684815.8545960406 632500.5997734013 704607.0531600439 746638.4808963928 729854.1246370046 672895.0335029798 755107.6220912633 722944.6813005126 1.1255309772704691 1.1772893222090253 0.9472589982460599 0.8748948794195283 0.9746348114665137 1.0327740146773847 1.0095573610474076 0.9307697406287048 1.0444887992437988 1.0 19.46352573286253 -5.261314345934359 24.99999672683022 0.973777376781772 1.1514101620639048 0.6688256036499507 0.04911148031991146 6.279699841540475 1255236.0327425636 0.013422366466522055 0.031194317837688692 5.478802611095741e-06 5.261314345934359 0.17763278528213278 QAAS(ph)PLEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QAASPLEPK 9 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;Q14980-4;Q14980-3;F5H6Y5;F5H4J1 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 QAAS(1)PLEPK;QAAS(1)PLEPK;QAAS(1)PLEPK;QAAS(1)PLEPK 112.64 0.0021543000000000005 69977000.0 506424.0 530253.0 475387.0 625714.0 659200.0 574330.0 661255.0 523264.0 542119.0 490206.0 True False 592151.5808700683 582893.0135200066 486722.02899523696 590657.2731721587 530034.4921067941 544211.1237498181 598616.1393283799 509528.87444403704 550046.4647866127 579076.46733144 1.0225792520958112 1.0065907464797428 0.8405142609890534 1.019998750586579 0.9153100186394275 0.9397914687462746 1.0337428182619555 0.879899120736335 0.9498684471178628 1.0 19.14339434381833 -5.028264672169381 24.947088973625533 0.9457740592993195 1.0185822294801241 0.18324761713427196 0.05709989669944881 899.0682099151452 793542.4950596747 0.013720552909476757 0.03649252849366817 9.369908024045448e-06 5.028264672169381 0.07280817018080465 QAAS(ph)PLEPK ddPTM_PC-9_Lapatinib_30min_R1 4 QAASPLEPK 9 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;Q14980-4;Q14980-3;F5H6Y5;F5H4J1 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 QAAS(1)PLEPK;QAAS(1)PLEPK;QAAS(1)PLEPK;QAAS(1)PLEPK 111.52 0.0022291999999999998 92522000.0 1120729.0 838173.0 939905.0 814088.0 937016.0 950953.0 940359.0 937291.0 1003103.0 817563.0 True False 1104747.1989434725 836232.2619156968 862629.63903822 873958.7472379581 881902.5611243348 910282.9569697146 989046.1878080764 980840.9616090237 890122.9769971257 958877.6752157813 1.152125268423697 0.8720948287043131 0.8996242809012087 0.9114392480159542 0.9197237394497433 0.94932125389703 1.031462316176572 1.0229052015297988 0.9282966951929678 1.0 19.87098725567003 -7.118581140939561 6.887887293613897 0.9973482736423125 0.9409154561382148 0.06830399931811415 0.07679077337722265 0.6057103488714717 32.00017903583829 0.029116955937694977 0.022538521230101236 7.610599339125817e-08 7.118581140939561 -0.056432817504097676 QADFEAHNILR ddPTM_PC-9_AZD4547_30min_R2 1 QADFEAHNILR 11 0 P49915-2;P49915 P49915-2 GMPS GMP synthase [glutamine-hydrolyzing] 0 157.68 3.4522e-12 0.0 13613.0 12879.0 18055.0 26903.0 22709.0 19205.0 16246.0 23022.0 15155.0 19660.0 False True 17941.650832010007 17041.884887428238 17815.578903072565 20700.928997206618 19556.247335873162 18004.10831401642 17691.862527327776 19464.4788929306 15956.062360454303 18971.709384038266 0.9457055486578931 0.8982788288843558 0.9390602893201387 1.0911472750380216 1.0308110323641524 0.9489976864796416 0.93253919133996 1.0259739119400029 0.8410450549004741 1.0 14.211562053489708 -5.538813946256335 24.996696886488852 0.9838489140080366 0.921161475107446 0.1317058749131359 0.06412489126003351 432.34805826179274 678199.0311730938 0.017676505597991412 0.03062831380132882 2.8919185281585566e-06 5.538813946256335 -0.0626874389005907 QADFEAHNILR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QADFEAHNILR 11 0 P49915-2;P49915 P49915-2 GMPS GMP synthase [glutamine-hydrolyzing] 0 ; 124.12 0.00044257 2845000.0 45627.0 50623.0 44750.9 54332.0 58214.0 49332.0 52730.0 52053.0 48198.0 42629.1 False True 53350.74992567227 55648.516884248216 45817.93117473333 51287.95418672062 46807.38459269558 46744.94307597734 47735.032667859596 50686.663904712404 48902.804568342384 50357.418378230046 1.0594417196878438 1.1050708848153654 0.9098546480401152 1.0184786241721409 0.9295032608925564 0.9282632942951974 0.9479245403194829 1.0065381732639553 0.9711142100462302 1.0 15.619916703345195 -5.252378400710283 24.99447059423453 0.9630620762343005 1.0822563137815284 0.6356801354621365 0.03581724698998244 387.4855671453245 1068863.9098180262 0.008975421344311344 0.022997638398145826 5.592700972015154e-06 5.252378400710283 0.11919423754722791 QADPQPQAWPPPDS(ph)PVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QADPQPQAWPPPDSPVR 17 0 Q63ZY3-3;Q63ZY3;Q63ZY3-2;K7ERU2 Q63ZY3-3 KANK2 KN motif and ankyrin repeat domain-containing protein 2 1 QADPQPQAWPPPDS(1)PVR 103.99 0.00081804 12941000.0 3869.3 6537.6 1953.1 3514.8 6165.6 3744.6 4106.8 3494.0 3730.9 1673.2 True False 4524.296067841491 7186.609722506786 1999.6693111729967 3317.877151135348 4957.494940129936 3548.2265840084483 3717.7741733427983 3402.286202199012 3785.45735433065 1976.5379149560874 2.289000394885927 3.6359584443723914 1.0117029863388294 1.6786306632570016 2.5081709298959116 1.7951725373744116 1.8809526218602266 1.721336168891352 1.915195921963759 1.0 10.94875991459547 -1.5228787452803376 0.10665547295150307 0.7821442490243083 6.190468796603083 0.27809170152916385 0.613122825641751 162.74848341421645 1.2226627112305097 6.462117445964056 129.2007099047635 0.029999999999999995 1.5228787452803376 5.408324547578775 QADPQPQAWPPPDS(ph)PVRVDTVR ddPTM_PC-9_AZD4547_30min_R2 2 QADPQPQAWPPPDSPVRVDTVR 22 1 Q63ZY3-3;Q63ZY3;Q63ZY3-2;K7ERU2 Q63ZY3-3 KANK2 KN motif and ankyrin repeat domain-containing protein 2 1 QADPQPQAWPPPDS(0.873)PVRVDT(0.127)VR;QADPQPQAWPPPDS(0.999)PVRVDT(0.001)VR 158.5 2.0321999999999998e-06 20298000.0 120613.0 108861.0 157818.0 220310.0 184889.0 161901.0 155687.0 172983.0 140788.0 162278.0 True False 158965.42509375006 144048.18935711798 155725.2302035505 169520.9332555695 159220.35376644746 151777.3048762078 169542.84139431722 146252.45210389225 148229.76625560145 156596.69661357932 1.0151262991582501 0.9198673565418417 0.9944349630044926 1.082531987720547 1.0167542305144681 0.9692241800651522 1.0826718893865561 0.9339434053630601 0.9465701988680882 1.0 17.256694253927364 -10.180592289796968 9.640101018492926 1.0000002986850474 0.9965523248148048 0.0003476881585087188 0.05349035065962736 0.0 0.0 0.05329827099710443 0.012926729469638583 6.597930099782571e-11 10.180592289796968 -0.0034479738702425378 QADPQPQAWPPPDS(ph)PVRVDTVR ddPTM_PC-9_Lapatinib_30min_R1 2 QADPQPQAWPPPDSPVRVDTVR 22 1 Q63ZY3-3;Q63ZY3;Q63ZY3-2;K7ERU2 Q63ZY3-3 KANK2 KN motif and ankyrin repeat domain-containing protein 2 1 QADPQPQAWPPPDS(0.995)PVRVDT(0.005)VR;QADPQPQAWPPPDS(0.619)PVRVDT(0.381)VR 136.77 2.6636e-07 19228100.0 234187.0 160106.0 214088.0 166643.0 203868.0 191777.0 160003.0 171256.0 218837.0 153827.0 True False 230847.4504353636 159735.2843938835 196486.51104357836 178898.48212475216 191876.88505990928 183575.14476402206 168287.17243930817 179213.17896076522 194189.2726042288 180415.79198840636 1.2795301779912815 0.8853730742381366 1.0890760109082065 0.9915899276502819 1.0635259970603872 1.017511509058025 0.932774069190808 0.9933342141816587 1.0763429878505733 1.0 17.460966099206487 -4.744669599166803 24.997944356906064 1.0073873544018555 1.2795309738073086 0.6546281326931858 0.059697770934042924 616.8234853944623 919421.3731305648 0.014208222098954695 0.39644035524519944 1.8002399737153434e-05 4.744669599166803 0.2721436194054532 QADSEMTGY(ph)VVTR ddPTM_PC-9_Lapatinib_30min_R1 2 QADSEMTGYVVTR 13 0 B5MDL5;P53778-2;P53778 B5MDL5 MAPK12 Mitogen-activated protein kinase 12 1 QADSEMT(0.004)GY(0.996)VVTR;QADSEMT(0.041)GY(0.956)VVT(0.003)R 171.62 0.00010282 5489200.0 14644.0 14740.900000000001 14794.8 10336.2 19738.6 17115.7 18862.6 15511.4 18788.2 18149.0 True False 14435.1738746193 14706.768351728198 13578.428653579533 11096.358628552416 18577.6143555807 16383.701409645431 19839.21313258936 16232.116271149718 16672.075067482987 21286.030467977613 0.6781524576099504 0.6909117401599534 0.6379032799942065 0.5212976954649019 0.8727608646209816 0.7696926599016584 0.9320297254312013 0.7625713162239935 0.7832402144009053 1.0 14.377619312988578 -6.276640978758624 24.893972613269337 0.8412589122144015 0.6366864647083661 0.6347527241484736 0.08190601655335594 519.4571418311554 850655.4061180814 0.024940987259456295 0.02838890078894814 5.288822859067653e-07 6.276640978758624 -0.20457244750603543 QADVFPDRDHFGR ddPTM_PC-9_AZD4547_30min_R2 1 QADVFPDRDHFGR 13 1 A0A0G2JM88;D6R9R1;D6RDF7;Q9HCC0-2;Q9HCC0 A0A0G2JM88 MCCC2 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial 0 71.268 0.011845999999999999 7083200.0 10666.0 11235.0 15756.0 21223.0 16825.0 17424.0 14886.0 22549.0 16214.0 18747.0 False True 14057.566133417977 14866.494037600449 15547.065145212478 16330.36524208139 14489.1391706401 16334.474525562198 16210.825161996881 19064.570174471908 17071.038938462945 18090.673236142695 0.7770615250146069 0.8217767157442888 0.8593967146646353 0.9026952744608504 0.8009176320587549 0.9029224237453004 0.8960874451930217 1.0538342009507695 0.9436375703452174 1.0 14.142958477744724 -7.386982599350928 1.7188105416641732 0.9984678032063893 0.8386989742875575 0.6914524938203623 0.04584747601799081 0.21110934303480014 1.2132074286201608 0.026522605794432243 0.014665614228696949 4.102205387483699e-08 7.386982599350928 -0.15976882891883182 QADVFPDRDHFGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QADVFPDRDHFGR 13 1 A0A0G2JM88;D6R9R1;D6RDF7;Q9HCC0-2;Q9HCC0 A0A0G2JM88 MCCC2 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial 0 ; 73.082 0.009959200000000001 8092700.0 56742.3 47469.0 56109.6 57419.3 77355.0 62407.0 54945.0 48545.0 49301.4 48043.2 False True 66347.65067849019 52181.40860830803 57447.46566084297 54202.2827768823 62197.84304751379 59134.26705875527 49740.21183264831 47270.74518767913 50022.3397059147 56753.05185023807 1.1690587292745185 0.9194467417541906 1.0122357087058038 0.9550549443563523 1.0959382979375913 1.04195748300551 0.8764323716705934 0.832919880897662 0.8814035206056476 1.0 15.792410353817688 -7.2636708318385 24.72056713452185 0.8837655918774872 1.0256250663849025 0.4209539337925323 0.07640173383677008 160.11426191587262 1773763.3340869115 0.030018799260684036 0.021340014254286468 5.449155083713391e-08 7.2636708318385 0.14185947450741532 QADVFPDRDHFGR ddPTM_PC-9_Lapatinib_30min_R1 1 QADVFPDRDHFGR 13 1 A0A0G2JM88;D6R9R1;D6RDF7;Q9HCC0-2;Q9HCC0 A0A0G2JM88 MCCC2 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial 0 63.966 0.019533000000000002 3589700.0 20558.0 14811.0 9825.2 12103.0 13644.0 10176.0 7468.7 6263.8 10982.0 7449.5 False True 20264.839150124528 14776.706039485125 9017.40998236879 12993.094994424428 12841.486745136091 9740.796201414592 7855.392741370239 6554.839015126134 9745.091514413196 8737.136149165202 2.3193914807039775 1.6912528072367259 1.0320784555051676 1.48711142559749 1.469759258171002 1.1148728868492321 0.8990809582520686 0.7502274089837117 1.115364502514282 1.0 13.092944756555038 -1.5228787452803383 0.47686183965931345 0.9859714486833724 35.915791623945005 0.7772425673798795 0.20829611268103973 49.532529352013036 0.5595762841238304 0.13436942383275075 1711.966782189881 0.02999999999999995 1.5228787452803383 34.92982017526163 up QAEEECAHR ddPTM_PC-9_Lapatinib_30min_R1 1 QAEEECAHR 9 0 F2Z2A4;H7C1J2;H7C1M5;Q9H147 F2Z2A4 DNTTIP1 Deoxynucleotidyltransferase terminal-interacting protein 1 0 92.538 0.0054248000000000005 0.0 3084.4 3420.4 2900.2 2826.9 3618.2 3465.0 3396.3 3356.0 3856.6 2688.3 False True 3040.4158903903144 3412.480273948749 2661.756751095747 3034.799656261956 3405.384589654894 3316.8100273095097 3572.14379577647 3511.9320116803415 3422.2290962015995 3152.969073065413 0.964302478055812 1.082306928761287 0.8442064255669675 0.9625212255289999 1.0800564517888136 1.0519640219892183 1.132946030550031 1.1138491784399058 1.0853988786113922 1.0 11.622495303603733 -6.2674438198775935 7.161592826534449 1.0847685909130889 0.9631349837499575 0.4370471392680486 0.06307878377221765 0.1275147325651953 46.247675216823296 0.019444653982472613 0.023271407061013386 5.402019905110682e-07 6.2674438198775935 -0.12163360716313132 QAEEECAHRGS(ph)PLPK ddPTM_PC-9_AZD4547_30min_R2 1 QAEEECAHRGSPLPK 15 1 F2Z2A4;H7C1J2;H7C1M5;Q9H147 F2Z2A4 DNTTIP1 Deoxynucleotidyltransferase terminal-interacting protein 1 1 QAEEECAHRGS(1)PLPK 58.29 0.027973 20565000.0 26114.0 22652.0 31146.0 43066.0 34898.0 33772.0 24136.0 30972.0 29074.0 35163.0 True False 34417.708795056904 29973.8160159969 30732.98368956513 33137.79906306733 30053.015083328286 31660.231501221697 26284.057242372477 26185.989065756512 30610.792284252595 33931.95407278422 1.014315554041796 0.8833507186678052 0.9057239563522549 0.976595659418452 0.8856847742651193 0.9330506410951264 0.7746107750232433 0.7717206326988251 0.9021228844820516 1.0 15.05035689388775 -7.226586197512781 24.31367251987958 0.8430902836875107 0.9294327042133607 0.1691386287739871 0.0720629220824369 606.5140398090662 423106.05516202527 0.026502396346057604 0.020527552011125005 5.934905422144279e-08 7.226586197512781 0.08634242052584995 QAEPELDLR ddPTM_PC-9_Lapatinib_30min_R1 1 QAEPELDLR 9 0 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;F8W7E0;E9PDE4;P20810-2;E9PCH5;P20810-3;H0Y7F0;H0Y9H6;E7EQ12;D6RC54;D6RAA8 P20810-6 CAST Calpastatin 0 122.33 0.007201000000000001 2210100.0 20463.0 19487.0 17936.0 17103.0 18952.0 17836.0 16681.0 17137.0 21127.0 15680.0 False True 20171.193867545386 19441.879048777715 16461.37131496218 18360.811673935474 17837.280621065598 17073.195857746723 17544.66055924014 17933.247581694275 18747.45478282715 18390.267107713316 1.096840722834586 1.0571830705288303 0.8951132258463983 0.9983983139774252 0.9699304809762235 0.9283821576787114 0.9540188000793904 0.9751488369721745 1.0194226474809613 1.0 14.166654813740564 -5.07443907102265 6.257396587875199 0.9661180918604992 1.087821523722463 0.6259830935393016 0.03442210323750103 0.12089186364562067 8.077395215746295 0.008637972061400073 0.024012170419814755 8.42482578529167e-06 5.07443907102265 0.12170343186196386 QAEQLS(ph)AAGEGGDAGR ddPTM_PC-9_AZD4547_30min_R2 1 QAEQLSAAGEGGDAGR 16 0 F8WBJ6;Q9NRX1 F8WBJ6 PNO1 RNA-binding protein PNO1 1 QAEQLS(1)AAGEGGDAGR 112.44 0.00034657 4999800.0 21020.0 15929.0 23281.0 31146.0 31513.0 22862.0 22748.0 22231.0 19588.0 24195.0 True False 27703.922756839092 21077.73774142745 22972.27872846483 23965.770900903142 27137.963903975105 21432.435525906967 24772.527931284763 18795.709767558856 20623.381690305432 23347.94041438483 1.186568162550668 0.9027664696472031 0.9839102859073363 1.0264618838130006 1.1623279579407877 0.9179582929165904 1.0610155539039425 0.805026457750367 0.8833062498994225 1.0 14.511007671025926 -7.750336839663506 24.996194735081083 0.883124755959367 1.0275558075115991 0.2954437679462435 0.09685936773560687 241.87953088973842 544569.2457888006 0.04461173468630791 0.025448205585278764 1.776900707724666e-08 7.750336839663506 0.14443105155223213 QAEQLS(ph)AAGEGGDAGR ddPTM_PC-9_Lapatinib_30min_R1 2 QAEQLSAAGEGGDAGR 16 0 F8WBJ6;Q9NRX1 F8WBJ6 PNO1 RNA-binding protein PNO1 1 QAEQLS(1)AAGEGGDAGR;QAEQLS(1)AAGEGGDAGR 145.43 2.9604e-05 6713700.0 16052.2 17418.3 17433.4 12325.6 14549.0 16751.6 15311.8 16211.3 18435.3 10614.9 True False 15823.292684387043 17377.96899652717 16000.093146870093 13232.065740996257 13693.256424434543 16035.173117886874 16104.570082787197 16964.536180260267 16358.922381684724 12449.671321534817 1.2709807573005325 1.3958576534038798 1.2851819725709492 1.0628445843472263 1.0998889907036047 1.2879997153137719 1.293573915877628 1.3626493215861741 1.3140043587647074 1.0 13.603820034368825 -5.528134914915269 24.996373484427426 1.2175008144394368 1.3351943850854555 0.17042955597634124 0.11575808912051723 263.42974120921554 1252769.389327756 0.03335606715028986 0.0580150607260295 2.9639104985892896e-06 5.528134914915269 0.11769357064601871 QAFPNTNR ddPTM_PC-9_Lapatinib_30min_R1 1 QAFPNTNR 8 0 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 0 90.709 0.04272 5358400.0 14368.0 10669.0 10719.0 9610.0 11453.0 10555.0 10713.0 8815.1 10620.0 7404.5 False True 14163.109685231493 10644.296586001401 9837.725196536565 10316.75145802023 10779.357057464347 10103.587254906746 11267.666720888425 9224.681727104698 9423.8637664422 8684.357959123927 1.630875851950748 1.2256860709913888 1.1328097301886193 1.1879693935440885 1.2412382248867782 1.1634236292956757 1.29746686789326 1.0622180442727027 1.085153768511043 1.0 13.084203478050606 -4.759443613191195 3.515864612619732 1.1599293946562115 1.7003428158898943 0.7538530176182014 0.08236579513488598 0.1554709819235999 3.081033169567598 0.020665723329126476 0.23220458508968558 1.7400286007264617e-05 4.759443613191195 0.5404134212336829 QAFQIGSPWR ddPTM_PC-9_Lapatinib_30min_R1 2 QAFQIGSPWR 10 0 P00352;Q5SYQ7;Q5SYQ9;Q5SYQ8 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ; 140.17 1.0484000000000002e-05 0.0 132131.0 205963.0 158369.0 134439.0 250900.0 206128.0 244160.0 204294.0 214125.0 273360.0 False True 130246.78771014226 205486.10532782876 145348.51214201853 144326.0925353573 236142.55528837914 197312.38594783662 256801.4101159447 213786.24505191424 190007.98766378852 320609.91177069594 0.4062469154206821 0.6409224973518438 0.45335002695104926 0.4501610438001089 0.7365416558215179 0.6154282157345055 0.8009777635933232 0.6668110909958914 0.5926453945681022 1.0 18.290459502054624 -14.522878744316117 0.06187658311018005 2.441703802209101 0.011522651084446915 0.6459279716823885 0.10199007198977139 249.64561715558676 1.1212822897089747 53.856988018258896 8.457409563971739 3.0000000066606017e-15 14.522878744316117 -2.430181151124654 QAGAPGGS(ph)SGSGGSPELSALR ddPTM_PC-9_Lapatinib_30min_R1 1 QAGAPGGSSGSGGSPELSALR 21 0 Q9Y2J4;Q9Y2J4-2;Q9Y2J4-4 Q9Y2J4 AMOTL2 Angiomotin-like protein 2 1 QAGAPGGS(0.354)S(0.213)GS(0.213)GGS(0.213)PELS(0.008)ALR 67.01899999999999 0.0038106999999999998 10229000.0 18280.0 19049.0 16263.0 15574.0 17174.0 13397.0 14231.0 15856.0 21208.0 11187.0 True False 18019.32384785856 19004.893210867067 14925.91891699543 16719.363913341003 16163.859085383114 12824.041539932321 14967.811547182224 16592.727645173854 18819.33170985934 13120.658044259482 1.3733551920242544 1.4484710406108054 1.1375892022066516 1.274277849246747 1.2319396657437534 0.9773931685951578 1.140782077902785 1.2646261787482118 1.4343283428602978 1.0 13.67955245723279 -5.259387467218288 24.998698408313622 1.1882795833687678 1.4109131324767927 0.3374305239295553 0.1277652985349642 208.3303609008222 2538068.4269131604 0.033917154422428604 0.08098412375371825 5.50316498015739e-06 5.259387467218288 0.2226335491080249 QAGAPGGSSGSGGS(ph)PELSALR ddPTM_PC-9_AZD4547_30min_R2 2 QAGAPGGSSGSGGSPELSALR 21 0 Q9Y2J4;Q9Y2J4-2;Q9Y2J4-4 Q9Y2J4 AMOTL2 Angiomotin-like protein 2 1 QAGAPGGSSGS(0.001)GGS(0.774)PELS(0.225)ALR;QAGAPGGS(0.001)S(0.026)GS(0.005)GGS(0.834)PELS(0.134)ALR 222.18 5.6218e-33 18700600.0 35208.0 28857.0 46315.0 54069.0 51164.0 47082.0 39110.0 52634.0 38602.0 44356.0 True False 46403.4116281061 38184.46092060845 45700.832838316586 41604.22740772273 44060.76175492598 44137.95509713727 42590.71423389076 44500.624708996154 40642.422912455106 42803.10994091563 1.0841130864593773 0.892095480289104 1.067698886865952 0.9719907610720854 1.0293822531995078 1.0311857049187365 0.9950378440417517 1.039658678316219 0.9495203261762268 1.0 15.385428001721147 -4.456777278572437 23.05717143437593 1.001202119120008 3.8556900642796927 0.22348774559734785 0.04802278169346455 782.012827714739 294050.45194695686 0.010633331273247927 8973.546682877872 3.493194127856521e-05 4.456777278572437 2.8544879451596845 QAGAPGGSSGSGGS(ph)PELSALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QAGAPGGSSGSGGSPELSALR 21 0 Q9Y2J4;Q9Y2J4-2;Q9Y2J4-4 Q9Y2J4 AMOTL2 Angiomotin-like protein 2 1 QAGAPGGSSGS(0.009)GGS(0.948)PELS(0.043)ALR;QAGAPGGS(0.001)S(0.002)GS(0.001)GGS(0.99)PELS(0.007)ALR;QAGAPGGS(0.027)S(0.012)GS(0.002)GGS(0.868)PELS(0.091)ALR;QAGAPGGSSGS(0.009)GGS(0.978)PELS(0.013)ALR 218.95 3.3396e-32 42255000.0 61231.0 67608.0 82285.0 85186.0 85393.7 80450.0 94429.0 89558.0 71729.0 63871.0 True False 71596.19893262394 74319.67543429373 84246.98646760047 80413.30459673813 68661.41748880468 76231.06037586913 85484.00151324332 87207.19739454487 72777.9009270642 75450.30669744227 0.9489185937934832 0.9850148884393222 1.1165890525194697 1.0657783661396847 0.9100217148770354 1.0103479192146654 1.1329841488390024 1.1558229676155996 0.9645805843958396 1.0 16.203239144714658 -7.154255442656341 10.818507130001489 1.076297440634173 1.0083873561828627 0.11233538070662341 0.0752334155924981 1.0110999888307481 96.11284650333782 0.029819168191891277 0.023097388931697563 7.010428388397844e-08 7.154255442656341 -0.0679100844513103 QAGAPGGSSGSGGS(ph)PELSALR ddPTM_PC-9_Lapatinib_30min_R1 1 QAGAPGGSSGSGGSPELSALR 21 0 Q9Y2J4;Q9Y2J4-2;Q9Y2J4-4 Q9Y2J4 AMOTL2 Angiomotin-like protein 2 1 QAGAPGGSS(0.003)GS(0.032)GGS(0.887)PELS(0.079)ALR 159.53 7.1095e-06 9824000.0 27178.0 20680.0 24234.0 19518.0 16718.0 24246.0 18534.0 17636.0 20440.0 15238.0 True False 26790.436736165193 20632.11673057542 22241.57406594522 20953.418830139304 15734.68010885262 23209.05510018656 19493.599832441505 18455.43294338334 18137.831957257855 17871.867996641304 1.4990283467402497 1.1544465712511336 1.244501921686369 1.1724246639510276 0.8804160881117559 1.2986362200385704 1.0907421561140098 1.0326527113367057 1.0148817102200247 1.0 14.1254028146365 -1.5228787452833896 0.5981576940394939 1.0643553165598085 25.734976893274062 0.5557959917490951 0.11208481552537439 134.08373136741142 1.0456495417751328 0.05056827331042173 4320.974288627358 0.02999999999978917 1.5228787452833896 24.670621576714254 QAGAPGGSSGSGGSPELS(ph)ALR ddPTM_PC-9_Lapatinib_30min_R1 1 QAGAPGGSSGSGGSPELSALR 21 0 Q9Y2J4;Q9Y2J4-2;Q9Y2J4-4 Q9Y2J4 AMOTL2 Angiomotin-like protein 2 1 QAGAPGGS(0.015)S(0.041)GS(0.113)GGS(0.314)PELS(0.517)ALR 89.65899999999999 0.00042727 13434000.0 21432.0 19834.0 20117.0 17094.0 19910.0 18822.0 16345.0 14546.0 19037.0 14699.0 True False 21126.375749852552 19788.07559159734 18463.05791386566 18351.149783912355 18738.93294456608 18017.026936224982 17191.264123300778 15221.860262783734 16892.85259150283 17239.702564813655 1.22544896992432 1.1478200112329624 1.0709615113400437 1.0644702085154978 1.0869638193649793 1.0450891985223603 0.9971902971451642 0.8829537635905418 0.979880744925452 1.0 14.073447263490962 -4.432146256635953 0.3410867418171426 0.9473046129153887 1.484473427169783 0.7820616716398908 0.04188566992930263 4.143397563353043 0.3227653851817481 0.044297242122654915 0.9632304212254081 3.697036543237835e-05 4.432146256635953 0.5371688142543943 QAGEVTYADAHK ddPTM_PC-9_Lapatinib_30min_R1 1 QAGEVTYADAHK 12 0 Q08170;A0A0D9SEM4;Q13247-3;Q13247;A0A590UJK4;A0A590UK01;A0A590UJP7;A0A590UK80 Q08170;Q13247-3 SRSF4;SRSF6 Serine/arginine-rich splicing factor 4;Serine/arginine-rich splicing factor 6 0 126.56 0.00021812 4408000.0 117920.0 130040.0 118670.0 123050.0 133450.0 118650.0 113830.0 120750.0 108750.0 108860.0 False True 116238.43917612029 129738.90036963382 108913.4106794473 132099.50748276673 125600.73337279464 113575.61608665886 119723.56042553253 126360.4858195476 96501.42981173153 127676.30595316776 0.9104151182033499 1.016154872284781 0.8530432476594149 1.0346438714417492 0.9837434787537286 0.889559070798296 0.93771165708262 0.9896940930128194 0.755828805441228 1.0 16.96213129035045 QAGEVTYADAHKER ddPTM_PC-9_AZD4547_30min_R2 1 QAGEVTYADAHKER 14 1 Q13247-3;Q13247;A0A590UJK4;A0A590UK01;A0A590UJP7;A0A590UK80 Q13247-3 SRSF6 Serine/arginine-rich splicing factor 6 0 71.933 0.010791 2232100.0 27013.0 16416.0 27876.0 52092.0 47023.0 27978.0 23326.0 32316.0 27310.0 36746.0 False True 35602.572094695264 21722.150967623395 27506.346026145166 40082.9942133772 40494.668126062956 26228.531237154442 25401.968811550392 27322.304747804083 28753.550845529997 35459.53372461192 1.0040338480250253 0.6125898647264608 0.7757108776377798 1.13038695107139 1.1419966331355402 0.7396750177498701 0.7163649981646338 0.7705207000181191 0.8108835008615072 1.0 15.113885945182192 QAGEVTYADAHKER ddPTM_PC-9_Lapatinib_30min_R1 1 QAGEVTYADAHKER 14 1 Q13247-3;Q13247;A0A590UJK4;A0A590UK01;A0A590UJP7;A0A590UK80 Q13247-3 SRSF6 Serine/arginine-rich splicing factor 6 0 54.898 0.034564 2408700.0 66123.0 30802.0 37035.0 34257.0 32966.0 32461.0 23537.0 24523.0 36427.0 29476.0 False True 65180.07389452692 30730.679861469256 33990.12525923419 36776.37405800197 31027.004693649687 31072.718700286885 24755.630692574516 25662.428105612933 32324.20766668455 34570.887325698815 1.8854035559010451 0.8889178797162409 0.9832008342454981 1.0637960695519573 0.8974893933539644 0.8988117200332457 0.716083173085697 0.7423132609771448 0.9350123808553747 1.0 15.077270013058833 -4.761183375249062 24.999999620687056 0.8962052036225543 1.8854046541921963 0.8929442213404032 0.1020404499900018 1.9951234074714563 194464.28278206722 0.028295072619742796 0.15994135653892347 1.733072075889462e-05 4.761183375249062 0.989199450569642 QAGGFLGPPPPS(ph)GKFS ddPTM_PC-9_AZD4547_30min_R2 1 QAGGFLGPPPPSGKFS 16 1 J3QQY2;Q9UM00-1;Q9UM00-2;Q9UM00 J3QQY2 TMCO1 Transmembrane and coiled-coil domain-containing protein 1 1 QAGGFLGPPPPS(0.982)GKFS(0.018) 122.1 0.0012494000000000001 0.0 20277.0 24100.0 30875.0 31015.0 25329.0 21750.0 26744.0 25105.0 22694.0 19445.0 True False 26724.664212199154 31889.853698813597 30465.577326633378 23864.970926973318 21812.50556036512 20389.969061695247 29124.164190007006 21225.599105508758 23893.558509280763 18764.236468597355 1.4242340346181348 1.69950180238788 1.6235980279623234 1.2718327743797213 1.1624510060331608 1.0866399544590377 1.5521102731116916 1.1311730770943216 1.2733562886647436 1.0 14.195697966583335 -5.808368202845318 5.253846783090071 1.220232462912812 1.5951031994741023 0.5549748451348296 0.15251727585811478 0.13864258421757067 8.518144064429169 0.04231759802745178 0.06550804968785227 1.554647014392493e-06 5.808368202845318 0.3748707365612902 QAGGFLGPPPPS(ph)GKFS ddPTM_PC-9_Lapatinib_30min_R1 1 QAGGFLGPPPPSGKFS 16 1 J3QQY2;Q9UM00-1;Q9UM00-2;Q9UM00 J3QQY2 TMCO1 Transmembrane and coiled-coil domain-containing protein 1 1 QAGGFLGPPPPS(0.812)GKFS(0.188) 140.75 9.6725e-07 0.0 66051.0 64935.0 27589.0 15612.0 19272.0 27041.0 23748.0 24121.0 34721.0 7752.6 True False 65109.10062773007 64784.64699709454 25320.738916619754 16760.15856010529 18138.458850209805 25884.519465649762 24977.555240143567 25241.749718039788 30810.35535166096 9092.626580309838 7.160648251928039 7.124965093957147 2.7847551742036822 1.8432692041262928 1.9948535981328868 2.846759320535929 2.747012100357523 2.7760680035734686 3.3884989204748663 1.0 13.150481389534802 -5.272431135244244 5.1944688441175035 2.458636835164009 7.199886410960191 0.9005862362263132 0.6279528213400805 0.04444822412529977 3.9896505557137405 0.1633711096996018 0.3887197967060403 5.34033947000327e-06 5.272431135244244 4.741249575796182 QAGGFLGPPPPSGKFS(ph) ddPTM_PC-9_AZD4547_30min_R2 1 QAGGFLGPPPPSGKFS 16 1 J3QQY2;Q9UM00-1;Q9UM00-2;Q9UM00 J3QQY2 TMCO1 Transmembrane and coiled-coil domain-containing protein 1 1 QAGGFLGPPPPS(0.203)GKFS(0.797) 135.36 3.611e-05 8729500.0 37977.0 27888.0 50499.0 36554.0 42518.0 26308.0 43611.0 42302.0 29484.0 34352.0 True False 50052.89602932815 36902.25062043625 49829.35026453955 28127.040053670244 36615.10961410259 24662.956601153033 47492.29451429841 35765.1979032556 31042.464047221012 33149.34693593503 1.5099210287931524 1.1132119945455983 1.503177433957917 0.8484945452478754 1.1045499534233827 0.743995248196505 1.4326766257592585 1.0789110860125242 0.9364427029954523 1.0 15.016692828120538 -5.758056134366435 24.999738979549104 1.0331393086112413 1.3492143318739742 0.39481211955371065 0.20004990441100234 98.1278894500038 725079.392231002 0.05380702935397825 0.0885541461302994 1.7455965127355023e-06 5.758056134366435 0.31607502326273296 QAGGFLGPPPPSGKFS(ph) ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QAGGFLGPPPPSGKFS 16 1 J3QQY2;Q9UM00-1;Q9UM00-2;Q9UM00 J3QQY2 TMCO1 Transmembrane and coiled-coil domain-containing protein 1 1 QAGGFLGPPPPS(0.475)GKFS(0.525) 97.713 0.010378 5760800.0 29621.0 28958.0 30723.0 30301.0 45987.0 25988.0 31941.0 21511.0 25663.0 25759.0 True False 34635.250258582375 31832.758863245177 31455.552837626332 28603.333207167456 36976.1774704417 24625.143530740654 28915.317247185743 20946.359042788463 26038.272825373904 30428.90279186819 1.138235265841997 1.046135612610789 1.0337393054485193 0.9400054087658857 1.2151663082746185 0.8092682046137224 0.9502582937335836 0.6883705004436165 0.8557085677217505 1.0 14.89315469351142 -6.781841066059419 24.999963746059052 0.8468402843059533 1.0633181387124546 0.5160363293888486 0.10286051767009251 192.83958182693686 236301.55056094602 0.035070129237427354 0.030963718124079647 1.6525664590222193e-07 6.781841066059419 0.21647785440650136 QAGIGGEPAAAGAGCS(ph)PRPK ddPTM_PC-9_AZD4547_30min_R2 2 QAGIGGEPAAAGAGCSPRPK 20 1 J3QQY0;J3KSZ8;Q68DK7 J3QQY0 MSL1 Male-specific lethal 1 homolog 1 QAGIGGEPAAAGAGCS(1)PRPK;QAGIGGEPAAAGAGCS(1)PRPK 92.147 0.00030119 55074000.0 83166.0 82319.0 123203.0 144795.0 126677.0 121898.0 114809.0 121283.0 101656.0 119561.0 True False 109611.05803973712 108927.00691421724 121569.24772058976 111414.7498104499 109090.08515418592 114275.69879000135 125026.77858549639 102541.49915608129 107029.32862516273 115375.20578153602 0.9500399786699981 0.944111052078828 1.053686074898815 0.9656732489076961 0.9455245120927365 0.9904701622494473 1.083653786258338 0.8887654714154489 0.9276631655836326 1.0 16.81597369548001 -7.81702489707818 24.999996504188793 0.931160934004045 0.9884229499777385 0.17366332909721927 0.05067105374633116 147.21809482365626 66210.10682042394 0.027746149923247174 0.01332883000168339 1.5239653859523614e-08 7.81702489707818 0.057262015973693514 QAGIGGEPAAAGAGCS(ph)PRPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QAGIGGEPAAAGAGCSPRPK 20 1 J3QQY0;J3KSZ8;Q68DK7 J3QQY0 MSL1 Male-specific lethal 1 homolog 1 QAGIGGEPAAAGAGCS(1)PRPK;QAGIGGEPAAAGAGCS(1)PRPK 157.12 7.4482e-06 32580000.0 69834.0 72967.0 88665.0 96982.0 114612.0 94523.0 100274.0 101019.0 86966.0 84067.0 True False 81655.51691562873 80210.68153789658 90779.1098638852 91548.41295988628 92154.60134912615 89566.04748176843 90775.32079910763 98367.3582884779 88237.7132264921 99307.68162599397 0.8222477413494995 0.8076986616199616 0.9141197174028439 0.9218663799309087 0.9279705239338154 0.9019045255641569 0.914081562602374 0.9905312124689665 0.8885285788747657 1.0 16.59961769664953 -2.2610331721291694 0.32401722032303387 0.9574667117678178 2.549571604568118e-19 0.6307345896405323 0.03530937252843803 22.758995067541367 0.5055855885758584 0.032552918298249224 11.89687146009268 0.005482350882208718 2.2610331721291694 -0.9574667117678178 QAGIGGEPAAAGAGCS(ph)PRPK ddPTM_PC-9_Lapatinib_30min_R1 2 QAGIGGEPAAAGAGCSPRPK 20 1 J3QQY0;J3KSZ8;Q68DK7 J3QQY0 MSL1 Male-specific lethal 1 homolog 1 QAGIGGEPAAAGAGCS(1)PRPK;QAGIGGEPAAAGAGCS(1)PRPK 109.4 4.0204e-05 65049000.0 89552.0 100012.0 111672.0 82126.0 108893.0 106170.0 87395.0 87293.0 104456.0 84061.0 True False 88274.97205817439 99780.4283587192 102490.75922638597 88165.8200043049 102488.12783187506 101629.35659435795 91919.88547298075 91348.9514587639 92691.06530955604 98590.831845758 0.8953669464547939 1.01206599529277 1.0395566941430139 0.894259824709029 1.0395300040901798 1.0308195467237118 0.9323370515504553 0.9265461072655946 0.9401590753851033 1.0 16.589165873357146 -7.294492786670985 24.894651662832867 0.9436393950816262 0.9872822663625167 0.09042255593577486 0.05355588358428199 1330.4177676700137 1002017.7705780969 0.022272018766083847 0.015016593701222108 5.075831695619864e-08 7.294492786670985 0.043642871280890505 QAHDLS(ph)PAAESSSTFSFSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 QAHDLSPAAESSSTFSFSGR 20 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 QAHDLS(0.997)PAAES(0.002)S(0.001)STFSFSGR;QAHDLS(0.998)PAAES(0.001)SSTFSFSGR;QAHDLS(0.998)PAAES(0.001)S(0.001)STFSFSGR;QAHDLS(0.996)PAAES(0.002)S(0.001)STFSFSGR;QAHDLS(0.999)PAAES(0.001)SSTFSFSGR 223.44 1.0095e-35 226128000.0 78512.3 72834.1 96552.0 113716.7 133103.0 114922.0 124526.0 110027.8 101991.1 92817.4 True False 91802.88170139058 80064.58810420208 98854.16585549896 107345.52197351576 107022.42263788047 108895.28801138134 112729.99578983303 107139.6868340905 103482.5268892954 109644.45987786588 0.8372778871239894 0.7302200967872601 0.9015883334699596 0.9790327946627587 0.9760860034067739 0.9931672620092338 1.0281412842509705 0.9771554983574594 0.9438007812211002 1.0 16.742473391704557 -5.511400882455867 3.1810785159832333 0.9858426538013464 0.7844679092606504 0.8604769438033091 0.032205563756168766 0.07821869312011535 1.6170730460828027 0.008773910811569956 0.018768971638475927 3.080343277495144e-06 5.511400882455867 -0.20137474454069604 QAHDLS(ph)PAAESSSTFSFSGR ddPTM_PC-9_Lapatinib_30min_R1 6 QAHDLSPAAESSSTFSFSGR 20 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 QAHDLS(1)PAAESSSTFSFSGR;QAHDLS(0.998)PAAES(0.001)SSTFSFSGR;QAHDLS(1)PAAESSSTFSFSGR;QAHDLS(0.999)PAAESSSTFSFSGR;QAHDLS(1)PAAESSSTFSFSGR;QAHDLS(1)PAAESSSTFSFSGR 86.91799999999999 0.00042137 262313400.0 142234.3 136129.7 152111.8 135006.3 149415.9 148755.8 139337.3 135388.2 164756.7 126526.8 True False 140206.012799424 135814.50004343383 139605.75497252838 144935.11366981422 140627.55052496179 142393.86120070665 146551.5036113551 141678.83003092385 146200.06548103451 148396.78879363663 0.9448048973242752 0.9152118529485165 0.9407599457335075 0.9766728434492186 0.9476455095030466 0.9595481301062534 0.9875651946562831 0.9547297565039976 0.9851969619392713 1.0 17.179100347786225 -1.522878746580801 0.1194010640851132 1.0151985131977035 0.7327532216039667 0.6286806075614957 0.014982876026505623 61.27377407179962 0.5053336091842447 0.10580256148561598 2.875668205231103 0.029999999910167174 1.522878746580801 -0.28244529159373677 QAHDLSPAAESSS(ph)TFSFSGR ddPTM_PC-9_AZD4547_30min_R2 1 QAHDLSPAAESSSTFSFSGR 20 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 QAHDLS(0.08)PAAES(0.178)S(0.045)S(0.348)T(0.348)FS(0.002)FSGR 160.47 7.2775999999999996e-06 5161900.0 15046.0 9383.7 18181.0 23911.0 24847.0 19079.0 14110.0 20903.0 16325.0 20102.0 True False 19830.31502375836 12416.797516745117 17939.908060745627 18398.68837126741 21397.422940439494 17885.987113934872 15365.762665308066 17672.921653154735 17187.906171851955 19398.235098572604 1.0222741874706711 0.6400993417003586 0.9248216639082653 0.9484722851215086 1.1030602955221425 0.9220419807805603 0.792121684639173 0.9110582258308219 0.8860551531884829 1.0 14.243637777819377 -5.48084022783108 24.99871932613446 0.9342310676162168 0.819005168216489 0.11797953461031485 0.11382390424963436 911.8579200821389 542245.8946536366 0.029615416530413007 0.061640370889137104 3.3049110272089776e-06 5.48084022783108 -0.11522589939972772 QAISGT(ph)SPVASSFQGIK ddPTM_PC-9_AZD4547_30min_R2 1 QAISGTSPVASSFQGIK 17 0 P51587;A0A590UJI7 P51587 BRCA2 Breast cancer type 2 susceptibility protein 1 QAIS(0.293)GT(0.578)S(0.128)PVAS(0.001)SFQGIK 157.47 6.8395e-05 3269200.0 11261.0 12191.0 15491.0 15068.0 17542.0 15024.0 15190.0 15387.0 16837.0 16892.0 True False 14841.763756649143 16131.502342001517 15285.579218360415 11594.305398279339 15106.596096960979 14084.546904961344 16541.88057307084 13009.292708084571 17726.96944658325 16300.616221524648 0.9105032322060856 0.9896253075819417 0.9377301453288682 0.7112801897003921 0.9267500008381899 0.8640499667959162 1.0148009344105413 0.7980859454200298 1.0875030247736972 1.0 13.992638884063068 -8.275089236157129 24.983538661150956 1.0437515265621136 0.8967571219952151 0.3248228238811035 0.08623341108103418 1068.596783771203 1955848.634483897 0.08076411770118234 0.02131046647282401 5.307753725689667e-09 8.275089236157129 -0.1469944045668985 QAISGTS(ph)PVASSFQGIK ddPTM_PC-9_AZD4547_30min_R2 1 QAISGTSPVASSFQGIK 17 0 P51587;A0A590UJI7 P51587 BRCA2 Breast cancer type 2 susceptibility protein 1 QAIS(0.002)GT(0.069)S(0.585)PVAS(0.133)S(0.211)FQGIK 90.73100000000001 0.0023361000000000002 3422600.0 10378.0 11104.0 12980.0 13046.0 14053.0 16975.0 13573.0 20073.0 14578.0 16267.0 True False 13677.98812419011 14693.150849445066 12807.87671901866 10038.44625869075 12101.983522437164 15913.550566541451 14780.970705614911 16971.179081652157 15348.563318423152 15697.497281289443 0.871348335284856 0.9360186905054284 0.8159183906523079 0.6394934223467602 0.77094987217243 1.0137635497799724 0.9416132037323567 1.0811391636220171 0.9777713633827348 1.0 13.938246941998289 -6.765745878921592 24.99758530884774 1.0041009208254288 0.80514535881462 0.612252711652709 0.07802542452028785 83.94698751823387 487276.7167551686 0.03027073580989021 0.027625861761339802 1.7149604980876025e-07 6.765745878921592 -0.19895556201080877 QALDS(ph)EEEEEDVAAK ddPTM_PC-9_AZD4547_30min_R2 1 QALDSEEEEEDVAAK 15 0 H7C3D5;Q8NC44 H7C3D5 FAM134A Protein FAM134A 1 QALDS(1)EEEEEDVAAK 81.594 0.008661 4096700.0 16534.0 18584.0 21334.0 17953.0 17329.0 20713.0 15096.0 19145.0 21118.0 17425.0 True False 21791.468071435647 24590.914570072695 21051.09722061203 13814.213221085014 14923.16747031336 19417.812835627283 16439.51475517298 16186.580158333607 22234.254366748533 16814.95605375722 1.29595747986308 1.4624429877458986 1.2519269841272207 0.8215432247887614 0.8874936944589189 1.1547941471597523 0.9776721808023785 0.9626299412609404 1.3222903643438542 1.0 14.037457387904913 -5.563713248740776 6.973904907997537 1.0155981390408706 1.3744643004422332 0.5461874347357936 0.13639217758825883 0.13492145115690574 17.570327956359705 0.037338065673534496 0.06569465091242443 2.7307802377041977e-06 5.563713248740776 0.3588661614013626 QALDS(ph)EEEEEDVAAK ddPTM_PC-9_Lapatinib_30min_R1 2 QALDSEEEEEDVAAK 15 0 H7C3D5;Q8NC44 H7C3D5 FAM134A Protein FAM134A 1 QALDS(1)EEEEEDVAAK;QALDS(1)EEEEEDVAAK 147.7 0.00012404 10721600.0 75878.0 100529.0 66317.0 48186.0 66169.0 69612.0 74102.0 67904.0 85315.0 50068.0 True False 74795.96580567914 100296.23127698326 60864.67225102297 51729.759183783855 62277.06951325929 66634.85703349765 77938.63897612935 71059.06773573946 75705.9262932219 58722.18708858356 1.2737258183665396 1.7079784703128384 1.0364851050116275 0.8809235784380529 1.0605372960532469 1.1347475347431744 1.3272434635065176 1.2100889162821111 1.2892218435089626 1.0 15.841618081434486 -5.274386806829298 24.96489335885374 1.122545849858805 1.4908521579687974 0.4650525424739351 0.16013517243871983 607.606252571448 1171570.8653962195 0.044184861120823586 0.09290048770127055 5.3163454503455544e-06 5.274386806829298 0.36830630810999243 QALDYVELS(ph)PLTQASPQR ddPTM_PC-9_AZD4547_30min_R2 1 QALDYVELSPLTQASPQR 18 0 Q9H2D6-5;Q9H2D6-7;Q9H2D6-3;Q9H2D6-2;Q9H2D6;F6WYE2;F6TR96;H0Y5J9;Q9H2D6-6 Q9H2D6-5 TRIOBP TRIO and F-actin-binding protein 1 QALDYVELS(0.994)PLT(0.004)QAS(0.002)PQR 129.2 1.6419e-05 0.0 1293.2 751.58 5419.0 7144.9 8390.6 5375.0 3700.5 7452.3 4782.2 6341.9 True False 1704.4106997689973 994.5135370520466 5347.140519288302 5497.7536926046 7225.710022298532 5038.900400303995 4029.837331181608 6300.718271817681 5034.977328945204 6119.872011324124 0.2785043047657173 0.16250561044607026 0.8737340436849054 0.898344554008913 1.1806962643872585 0.8233669578350798 0.6584839231482055 1.029550660562659 0.8227259196971037 1.0 12.57928576592008 -5.272862154464645 10.498001868413615 0.9091066743780474 0.22031512330977643 0.807101329012882 0.13499842248074093 0.13777391385023957 125.06600477745805 0.036173261617024596 0.07953779613900026 5.335042034245404e-06 5.272862154464645 -0.688791551068271 QALDYVELSPLT(ph)QASPQR ddPTM_PC-9_Lapatinib_30min_R1 1 QALDYVELSPLTQASPQR 18 0 Q9H2D6-5;Q9H2D6-7;Q9H2D6-3;Q9H2D6-2;Q9H2D6;F6WYE2;F6TR96;H0Y5J9;Q9H2D6-6 Q9H2D6-5 TRIOBP TRIO and F-actin-binding protein 1 QALDYVELSPLT(0.5)QAS(0.5)PQR 85.881 0.003774 1216000.0 18625.0 13886.0 14674.0 14694.0 13053.0 13026.0 10002.0 11625.0 13045.0 9172.1 True False 18359.404084593316 13853.847820153293 13467.560363278046 15774.645777747062 12285.248203185376 12468.908345089087 10519.854619838143 12165.139939148969 11575.734730060125 10757.485263944976 1.7066631869928837 1.2878333067846397 1.2519245932333476 1.4663878583796635 1.1420185946580734 1.1590913711850626 0.9779102050082948 1.1308535071781058 1.0760632662781897 1.0 13.39305324357278 -1.5228787452811698 0.28209007096912886 1.009822658702941 5.618148059235861 0.7454739224538289 0.10685900661488085 27.820209722692546 0.3927635377773072 0.12068398942052648 63.34873832746619 0.029999999999942507 1.5228787452811698 4.60832540053292 QALDYVELSPLTQAS(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 2 QALDYVELSPLTQASPQR 18 0 Q9H2D6-5;Q9H2D6-7;Q9H2D6-3;Q9H2D6-2;Q9H2D6;F6WYE2;F6TR96;H0Y5J9;Q9H2D6-6 Q9H2D6-5 TRIOBP TRIO and F-actin-binding protein 1 QALDYVELSPLTQAS(1)PQR;QALDYVELSPLTQAS(1)PQR 324.71 9.346699999999997e-177 48428000.0 94539.0 105411.0 164600.0 208350.0 216130.0 179359.0 152101.0 193630.0 160817.0 187692.0 True False 124600.43546664188 139483.04432554508 162417.29645227047 160318.1264754117 186124.0801753608 168143.65337639552 165637.69434132 163708.93267475272 169317.45830558735 181120.9602089989 0.6879404532907902 0.7701098987361427 0.896733852696309 0.8851439738968785 1.0276230865858302 0.9283500550260521 0.9145142238103614 0.9038651986266298 0.9348308341022967 1.0 17.466593986157235 -5.098132744752747 1.3775657543274324 0.9418965274588768 0.6498288749974575 0.8273609683144432 0.039492750453312346 0.29901588063101364 0.7592366260641852 0.012108331696664526 0.10366370796686952 7.977508126057306e-06 5.098132744752747 -0.2920676524614193 QALDYVELSPLTQAS(ph)PQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QALDYVELSPLTQASPQR 18 0 Q9H2D6-5;Q9H2D6-7;Q9H2D6-3;Q9H2D6-2;Q9H2D6;F6WYE2;F6TR96;H0Y5J9;Q9H2D6-6 Q9H2D6-5 TRIOBP TRIO and F-actin-binding protein 1 QALDYVELSPLTQAS(1)PQR;QALDYVELSPLTQAS(1)PQR 320.13 6.482399999999997e-157 38069000.0 76661.0 60441.0 80364.0 93538.0 106406.0 85023.0 80904.0 67920.0 72281.0 64315.0 True False 89638.19317623263 66441.18303934658 82280.18254216708 88297.36911428769 85556.5081418623 80564.24420556278 73240.18742576367 66137.17196718861 73337.97288278263 75974.80038274026 1.179841114746731 0.8745160593332799 1.082993073067149 1.1621928411719373 1.1261169191738842 1.0604074482552392 0.9640063159995109 0.8705145868631129 0.9652933935110851 1.0 16.213233358744745 -7.2846119035862635 3.6945873474069377 0.9355842965046396 1.0786940064945099 0.36862864154373476 0.0840657221505396 0.26049629375916616 7.794786941348347 0.03749704528798836 0.025606903373726217 5.192638588321926e-08 7.2846119035862635 0.14310970998987027 QALDYVELSPLTQAS(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 1 QALDYVELSPLTQASPQR 18 0 Q9H2D6-5;Q9H2D6-7;Q9H2D6-3;Q9H2D6-2;Q9H2D6;F6WYE2;F6TR96;H0Y5J9;Q9H2D6-6 Q9H2D6-5 TRIOBP TRIO and F-actin-binding protein 1 QALDYVELSPLT(0.061)QAS(0.939)PQR 153.57 1.1108e-05 1177400.0 15361.0 11576.0 11103.0 11206.0 10265.0 12282.0 8041.7 8574.1 11424.0 7489.8 True False 15141.949323137596 11549.196483227322 10190.154198819422 12030.126622120148 9661.232881766484 11756.727490740377 8458.059877659698 8972.483987290943 10137.308819946855 8784.401950468826 1.723731383025963 1.3147390736840017 1.1600282246050422 1.3694872673122724 1.0998168044041816 1.338364018066468 0.9628498246495072 1.0214109096877197 1.1540124048405849 1.0 13.100728354337702 -1.5228787452803376 0.49171981418022076 1.0848687346265045 18.462678754536512 0.6927315076493881 0.12082701757472415 61.89592186812238 0.6726884868518659 0.06851553569462861 1106.351946239833 0.029999999999999995 1.5228787452803376 17.377810019910008 QALPCVAES(ph)PTVHVEVHQR ddPTM_PC-9_AZD4547_30min_R2 2 QALPCVAESPTVHVEVHQR 19 0 Q15645-2;Q15645 Q15645-2 TRIP13 Pachytene checkpoint protein 2 homolog 1 QALPCVAES(0.991)PT(0.009)VHVEVHQR;QALPCVAES(0.922)PT(0.078)VHVEVHQR 82.26700000000001 0.0016434999999999998 23394000.0 56175.0 61711.0 84604.0 108790.0 88132.0 81036.0 77292.0 106995.0 78056.0 79395.0 True False 74037.48148741366 81657.87392562171 83482.09568072834 83710.14628874499 75896.3930690552 75968.80610958803 84170.83826555581 90461.38125050433 82181.88080551763 76615.40521595711 0.966352410180733 1.0658153369475931 1.0896254538550827 1.0926020172155952 0.9906153058268735 0.9915604557001754 1.0986150634888907 1.1807205221393704 1.0726547823361399 1.0 16.225346886505157 -7.376755009041264 8.394666811089492 1.1036995174329036 1.0377249818261098 0.15597110277872772 0.0579607812981808 0.4902170952251957 32.707802364440795 0.024749740249520764 0.016639924077850976 4.199958420942795e-08 7.376755009041264 -0.06597453560679378 QALPCVAES(ph)PTVHVEVHQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QALPCVAESPTVHVEVHQR 19 0 Q15645-2;Q15645 Q15645-2 TRIP13 Pachytene checkpoint protein 2 homolog 1 QALPCVAES(0.997)PT(0.003)VHVEVHQR;QALPCVAES(0.989)PT(0.011)VHVEVHQR 145.13 2.3833e-05 11199200.0 26883.0 24374.0 32527.0 36846.0 34250.0 31315.0 32587.0 27901.0 24739.0 20142.7 True False 31433.76093654739 26793.689637845746 33302.567039334426 34781.63807634375 27538.958365682218 29672.78627309312 29500.123450550753 27168.628313553123 25100.761073410165 23794.412060474533 1.3210564252084531 1.1260496611451638 1.3995961301625988 1.4617565665394339 1.1573708270534593 1.2470485170080454 1.2397920728436116 1.1418070866597954 1.0549015041689405 1.0 14.538335186730476 -7.958540335490699 0.8559370368683871 0.9943281499516169 1.2991847323712367 0.560758401459833 0.09285669945231378 0.46490519674389014 0.65252890835148 0.09050272064177504 0.03651701581348332 1.1001696613035841e-08 7.958540335490699 0.30485658241961977 QALPCVAES(ph)PTVHVEVHQR ddPTM_PC-9_Lapatinib_30min_R1 2 QALPCVAESPTVHVEVHQR 19 0 Q15645-2;Q15645 Q15645-2 TRIP13 Pachytene checkpoint protein 2 homolog 1 QALPCVAES(0.992)PT(0.008)VHVEVHQR;QALPCVAES(0.996)PT(0.004)VHVEVHQR 90.30799999999999 0.00086712 19052000.0 70925.0 76534.0 95158.0 71985.0 85780.0 81463.0 70522.0 72201.0 86199.0 60726.0 True False 69913.59649394797 76356.79022523493 87334.47656050237 77279.01703492065 80734.5890499688 77979.01738952808 74173.28409320381 75555.72204270924 76490.3609042891 71222.40818769112 0.9816235967436813 1.0720894191616388 1.2262218981749593 1.085037967703488 1.1335560128381281 1.0948663401556344 1.0414318468105754 1.0608420013487696 1.073964821615066 1.0 16.12004359679637 -7.184809560469662 4.853466496309586 1.0491519955664454 1.105109418823627 0.16376286565051168 0.05956969609948503 0.44014280102287556 19.008575055743723 0.02432535066119258 0.01851178006289437 6.534170153030961e-08 7.184809560469662 0.05595742325718156 QALQS(ph)TPLGSSSK ddPTM_PC-9_AZD4547_30min_R2 2 QALQSTPLGSSSK 13 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3 O15027 SEC16A Protein transport protein Sec16A 1 QALQS(0.499)T(0.499)PLGSSSK;QALQS(0.708)T(0.292)PLGSSSK 191.01 1.3482e-05 14927700.0 60356.0 62552.0 71368.0 81465.0 79504.0 90871.0 82300.0 108881.0 92769.0 79200.0 True False 79547.95251721123 82770.71072897041 70421.61368897716 62684.50287170338 68466.24193893434 85188.82200484157 89624.54056377403 92055.94328647296 97672.57994833293 76427.2321066038 1.0408325713831232 1.08300024019604 0.9214204380808956 0.8201854384085047 0.8958356864662436 1.1146396337632214 1.1726780899086087 1.204491393304282 1.2779813851180069 1.0 16.2217991621161 -6.906086929915361 4.478468754710756 1.1766394260874626 0.9511731789872929 0.5344401420189154 0.09448632428324621 0.17440997267013292 6.235042849426801 0.0368186576269658 0.03222310640432636 1.2414037989589232e-07 6.906086929915361 -0.22546624710016971 QALQS(ph)TPLGSSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QALQSTPLGSSSK 13 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3 O15027 SEC16A Protein transport protein Sec16A 1 QALQS(0.682)T(0.317)PLGS(0.001)SSK 108.23 0.0017534000000000002 0.0 27573.0 32359.0 28677.0 24556.0 31996.0 23196.0 30486.0 24937.0 21954.0 22045.0 True False 32240.564308426194 35571.3876668192 29360.768438128114 23180.20693162616 25726.613485207836 21979.56092577575 27598.145380473517 24282.43017293552 22275.03571711252 26041.583991876018 1.238041599869041 1.3659456228897644 1.1274570873756202 0.8901227720578556 0.9879050941460995 0.8440178190632542 1.0597721470814943 0.9324482788954279 0.855364087071719 1.0 14.668529583341908 -5.5375017081400255 3.5979545929602814 0.9395966861581412 1.297953970960462 0.814936209810268 0.06981368120073597 0.08373643447558353 2.3216305329571827 0.018558842132358925 0.03731327054533158 2.900669789936839e-06 5.5375017081400255 0.35835728480232076 QALQST(ph)PLGSSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QALQSTPLGSSSK 13 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3 O15027 SEC16A Protein transport protein Sec16A 1 QALQS(0.23)T(0.77)PLGSSSK;QALQS(0.026)T(0.965)PLGS(0.006)S(0.003)SK 146.84 0.00015781 9846700.0 66132.0 77409.0 66030.0 60890.0 70359.0 50480.0 63490.0 53569.0 50525.0 43822.0 True False 77326.84143346183 85093.65394174133 67604.40562016932 57478.530708043494 56572.65902630757 47832.739935038815 57475.767572205674 52162.870511047186 51263.832541090946 51766.58170523885 1.4937598521332585 1.6437951114150875 1.3059468752468864 1.1103404709109195 1.0928413111847857 0.924008083195458 1.110287094084658 1.007655301794212 0.9902881521710167 1.0 15.659733435632798 -5.598687783631489 1.8926750668293688 1.023340017114447 1.5792052324602022 0.9178528159411025 0.06465540590581013 0.08331003450971433 0.5934112295888986 0.018579112760290825 0.045347956896281454 2.519487548430024e-06 5.598687783631489 0.5558652153457551 QANS(ph)S(ph)VPQRS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 QANSSVPQRSR 11 1 Q68DE3 Q68DE3 KIAA2018 Basic helix-loop-helix domain-containing protein KIAA2018 3 QANS(1)S(1)VPQRS(1)R 58.626000000000005 0.03936 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 QAPFRS(ph)PTAPSVFSPTGNR ddPTM_PC-9_AZD4547_30min_R2 2 QAPFRSPTAPSVFSPTGNR 19 1 H0Y3X6;A0A0C4DFX9;Q9H3P2;C9JEM7;H7C2C7;C9JHL4 H0Y3X6 NELFA Negative elongation factor A 1 QAPFRS(0.996)PT(0.004)APSVFSPTGNR;QAPFRS(0.999)PT(0.001)APSVFSPTGNR 85.7 0.00060356 52225000.0 39437.0 38995.0 70960.0 69903.0 63185.0 53092.0 56532.0 63649.0 65118.0 51129.0 True False 51977.14565944166 51599.37116121314 70019.02403555962 53787.94334058402 54412.85340249004 49772.14884705858 61563.23848300462 53813.50955851531 68560.00453896818 49338.989272456376 1.0534700127807044 1.0458132994227878 1.4191418403183205 1.090171163490195 1.1028368072563286 1.008779255128439 1.247760430256168 1.0906893382300566 1.3895705110692647 1.0 15.590440541345767 QAPFRS(ph)PTAPSVFSPTGNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QAPFRSPTAPSVFSPTGNR 19 1 H0Y3X6;A0A0C4DFX9;Q9H3P2;C9JEM7;H7C2C7;C9JHL4 H0Y3X6 NELFA Negative elongation factor A 1 QAPFRS(0.986)PT(0.009)APS(0.004)VFSPT(0.001)GNR;QAPFRS(0.875)PT(0.123)APS(0.001)VFSPTGNR 77.795 0.0015577 22006800.0 20567.6 14155.099999999999 12981.400000000001 12632.2 19427.7 16439.0 18639.8 19166.0 19660.2 14868.5 True False 24049.288451383087 15560.324780203098 13290.925808233653 11924.458788144973 15620.981647911363 15576.909900794435 16874.103203534418 18662.912808055597 19947.69323155577 17564.041351018772 1.3692343334176988 0.8859193888939774 0.7567122817928652 0.6789131584146103 0.8893728576313842 0.8868636545250973 0.9607187130970666 1.0625637024575263 1.135712039894437 1.0 14.100337215667164 -7.620036689108029 2.63225878321819 1.0780376286401867 0.8919419729144554 0.131100571481522 0.1735298633987596 0.5367485560958564 7.473877752495695 0.10391670676769041 0.05250426456069289 2.398630274670312e-08 7.620036689108029 -0.18609565572573128 QAPFRS(ph)PTAPSVFSPTGNR ddPTM_PC-9_Lapatinib_30min_R1 2 QAPFRSPTAPSVFSPTGNR 19 1 H0Y3X6;A0A0C4DFX9;Q9H3P2;C9JEM7;H7C2C7;C9JHL4 H0Y3X6 NELFA Negative elongation factor A 1 QAPFRS(0.986)PT(0.012)APS(0.001)VFSPTGNR;QAPFRS(0.989)PT(0.008)APS(0.003)VFSPTGNR 83.25200000000001 0.007707600000000001 16212800.0 28538.6 23536.5 27798.0 19331.3 23527.1 22710.8 19948.1 23151.9 22946.8 20968.8 True False 28131.634330661724 23482.002680328238 25512.555743383084 20752.98828932638 22143.28223405828 21739.51202546055 20980.91501119708 24227.621794166294 20362.289743483594 24593.229140830288 1.1438772098437813 0.9548157562336064 1.0373812888615959 0.8438496697805232 0.9003812434413281 0.8839633014831743 0.8531175345479153 0.985133820997219 0.8279632425201787 1.0 14.585973555703562 -2.471161678481478 0.7653818128732718 0.8996648118081509 9.938219222231389 0.5352293445703958 0.06498679533289779 59.05685908887166 1.1908277404537373 0.022542953601959514 870.0264889365674 0.003379390053724439 2.471161678481478 9.038554410423238 QAPGKGLEWVSAISGS(ph)GGST(ph)Y(ph)Y(ph)ADS(ph)VK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QAPGKGLEWVSAISGSGGSTYYADSVK 27 1 P01764 P01764 IGHV3-23 Ig heavy chain V-III region 23 5 QAPGKGLEWVS(0.117)AIS(0.117)GS(0.769)GGS(0.495)T(0.549)Y(0.985)Y(0.985)ADS(0.985)VK 40.141999999999996 0.040881 0.0 1726.8 3488.4 5480.7 5435.7 5253.4 3616.2 3543.9 5007.3 4174.7 3150.1 True False 2019.1131341453722 3834.7052979675527 5611.380673670493 5131.155351777172 4224.033981847442 3426.560106043727 3208.196136385886 4875.863680672897 4235.747089743536 3721.188193822122 0.5425990379893936 1.0305056068741405 1.507954013985761 1.378902405499368 1.1351304373318554 0.9208241904380076 0.862142941792651 1.3102975250667934 1.1382781168594696 1.0 11.861547639229041 -6.551283991466315 24.493153763142608 1.051279043760086 1.1520235840618391 0.011293541600323254 0.26351570223293175 832.8248041236542 718117.5606556827 0.09424840022060414 0.09424984579605482 2.8100626886852065e-07 6.551283991466315 0.10074454030175306 QAPLPS(ph)PESLDLGR ddPTM_PC-9_AZD4547_30min_R2 2 QAPLPSPESLDLGR 14 0 H3BRS1;Q12968 H3BRS1 NFATC3 Nuclear factor of activated T-cells, cytoplasmic 3 1 QAPLPS(0.718)PES(0.282)LDLGR;QAPLPS(0.96)PES(0.04)LDLGR 103.13 0.0012894 9687600.0 26292.7 21581.4 25857.0 41139.0 30651.8 33092.0 22935.2 30211.0 27221.4 29601.0 True False 34653.231677866 28557.165502720985 25514.11928533634 31655.039141214096 26396.326658581038 31022.75200871811 24976.388368630298 25542.584129716204 28660.267630410483 28564.67799984319 1.2131497396209485 0.9997370004618206 0.8932052125872522 1.1081882015749616 0.9240897677448332 1.0860529220349837 0.8743801827126289 0.8942017175847886 1.0033464277303534 1.0 14.80194464653948 -4.770663310794362 4.468900540277868 0.9712338382586111 1.2316892231075187 0.4711911271360205 0.07581435482823196 0.1691130026185063 7.381836919629352 0.018517080121856634 0.14033985336614838 1.6956518545217505e-05 4.770663310794362 0.2604553848489076 QAPLPS(ph)PESLDLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QAPLPSPESLDLGR 14 0 H3BRS1;Q12968 H3BRS1 NFATC3 Nuclear factor of activated T-cells, cytoplasmic 3 1 QAPLPS(1)PESLDLGR;QAPLPS(0.861)PES(0.139)LDLGR 130.87 1.8128e-05 5849800.0 28319.7 28065.8 26172.6 33102.0 33827.9 27621.3 31864.8 26580.4 27859.4 22907.7 True False 33113.66587042892 30851.987143589533 26796.654044138242 31247.40225813197 27199.565830612013 26172.790403480354 28846.335462825973 25882.69266426176 28266.79102019333 27060.684672746585 1.223681746078599 1.1401037156558442 0.9902430174328052 1.1547158778876692 1.0051322115291967 0.967188772937425 1.0659869035715033 0.9564685068862574 1.0445704298332643 1.0 14.723910721505437 -1.5228787496906702 0.5250259274656901 1.0065296959813486 9.366787577520652 0.5990809343596802 0.05409650528325206 80.51189019012561 0.7962689320641356 0.02746768707473919 751.2049235454639 0.029999999695345017 1.5228787496906702 8.360257881539304 QAPLPS(ph)PESLDLGR ddPTM_PC-9_Lapatinib_30min_R1 1 QAPLPSPESLDLGR 14 0 H3BRS1;Q12968 H3BRS1 NFATC3 Nuclear factor of activated T-cells, cytoplasmic 3 1 QAPLPS(0.89)PES(0.11)LDLGR 121.32 7.3905e-05 4732400.0 14581.0 15239.0 16107.0 12577.0 18710.0 19398.0 18425.0 16725.0 17748.0 13427.0 True False 14373.072266172077 15203.715031781368 14782.744634818013 13501.954535642084 17609.51458527529 18568.392758946575 19378.956345782604 17502.104557614333 15749.033345274589 15747.839059647107 0.9127012418486173 0.9654477020113811 0.9387157551475053 0.8573845900063859 1.1182178404654017 1.1791073485458057 1.2305787652758033 1.1113972203629148 1.0000758380640644 1.0 13.942866253125802 -6.274569319549285 24.249500652513078 1.1219607391682929 0.923350812561052 0.6184779092574672 0.07168873591636149 339.4458460734313 626916.3644307108 0.02308547246307436 0.026345902256061007 5.314111719887149e-07 6.274569319549285 -0.19860992660724086 QAPLPSPES(ph)LDLGR ddPTM_PC-9_Lapatinib_30min_R1 1 QAPLPSPESLDLGR 14 0 H3BRS1;Q12968 H3BRS1 NFATC3 Nuclear factor of activated T-cells, cytoplasmic 3 1 QAPLPS(0.425)PES(0.575)LDLGR 113.43 0.00020945 4096300.0 12762.0 17400.0 18818.0 10044.0 18030.0 16938.0 15939.0 14125.0 18060.0 15322.0 True False 12580.01153973583 17359.711369052806 17270.85667958065 10782.66926580178 16969.51084834386 16213.601224406482 16764.24342987403 14781.299065847677 16025.892619768942 17970.387284718327 0.7000412033653627 0.9660176541556882 0.9610731480599451 0.6000243119396295 0.9443041254194008 0.9022399443886342 0.9328815881519716 0.8225364780211171 0.8917945042507266 1.0 14.133333880646708 QAPPHIELSNS(ph)SPDPMAEAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QAPPHIELSNSSPDPMAEAER 21 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 QAPPHIELSNS(0.5)S(0.5)PDPMAEAER;QAPPHIELS(0.021)NS(0.791)S(0.188)PDPMAEAER;QAPPHIELS(0.001)NS(0.913)S(0.085)PDPMAEAER 125.91 6.3111000000000004e-06 50467800.0 62802.0 62767.0 74730.0 87987.0 92041.0 83874.0 71194.0 81660.0 78628.0 62692.7 True False 73433.13820395975 68998.0929473482 76511.84661510318 83057.37364770268 74006.22677184697 79475.49978826163 64449.98892007586 79516.51152592206 79777.7857504383 74058.39023485983 0.9915573099966495 0.9316715193043756 1.03312867552836 1.1215120040322852 0.9992956441147661 1.07314646640607 0.8702591119748478 1.0737002421164301 1.0772281911264971 1.0 16.176375570357603 -5.2772510821484 23.618882776344883 1.0315258815369188 0.9616144211178129 0.15043680338731602 0.06597917697661523 644.8035943604749 963182.891944356 0.017455313573792517 0.03656490794211519 5.28139825785551e-06 5.2772510821484 -0.0699114604191059 QAPPHIELSNS(ph)SPDPMAEAER ddPTM_PC-9_Lapatinib_30min_R1 1 QAPPHIELSNSSPDPMAEAER 21 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 QAPPHIELSNS(0.5)S(0.5)PDPMAEAER 83.24700000000001 0.00038072 15590000.0 30787.0 25214.0 32932.0 28284.0 32680.0 32981.0 29156.0 25445.0 32073.0 22520.0 True False 30347.97173435566 25155.61853214355 30224.45808119618 30364.099712658077 30757.826651352065 31570.479512466074 30665.555018596366 26627.267591539417 28460.600996337158 26412.551993986202 1.1489980877752934 0.9524115101740703 1.1443217636856104 1.1496087057233846 1.1645155174083603 1.1952831941288469 1.1610220407925185 1.0081293014625055 1.0775407466426292 1.0 14.688936081705585 -7.764314811878837 24.999796142749446 1.0321262528925346 1.1290239697354167 0.3398262251667383 0.06526325854686316 100.47635968470199 873536.0813027853 0.03637323996009049 0.01866721401634052 1.7206208772025634e-08 7.764314811878837 0.09689771684288218 QAPPHIELSNSS(ph)PDPMAEAER ddPTM_PC-9_AZD4547_30min_R2 4 QAPPHIELSNSSPDPMAEAER 21 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 QAPPHIELSNS(0.377)S(0.623)PDPMAEAER;QAPPHIELS(0.036)NS(0.401)S(0.563)PDPMAEAER;QAPPHIELSNS(0.046)S(0.954)PDPMAEAER;QAPPHIELSNS(0.002)S(0.998)PDPMAEAER 241.06 5.802099999999999e-52 57653100.0 70343.0 66764.9 110409.0 133300.0 123387.0 112289.0 104457.0 129415.0 92863.0 107034.0 True False 92710.6107747064 88345.34826622072 108944.90452004099 102569.74446447006 106256.844864652 105267.5510790208 113753.47063997755 109416.8854108509 97771.54859642801 103286.77223861401 0.8976039115689037 0.8553403921087255 1.0547808026022492 0.9930578934881664 1.0287555953358336 1.0191774686871886 1.1013362909355253 1.0593504186390397 0.9466028076717832 1.0 16.656295976967904 -5.260370460776755 24.998980030009346 1.0289593411716276 0.8764721403919493 0.6789563722628373 0.0408996058017233 50.041366590291325 1170286.7920908493 0.010654667784553713 0.025149424043496273 5.490723057728801e-06 5.260370460776755 -0.15248720077967826 QAPPHIELSNSS(ph)PDPMAEAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QAPPHIELSNSSPDPMAEAER 21 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 QAPPHIELS(0.009)NS(0.223)S(0.768)PDPMAEAER 65.023 0.0030783 4916200.0 14244.0 15581.0 13475.0 19631.0 17663.0 15818.0 16615.0 12758.0 13863.0 12657.0 True False 16655.227868176193 17127.778708758306 13796.295104222085 18531.13871456072 14202.061944906418 14988.476234002459 15041.106917816944 12423.116018218368 14065.720148780674 14951.613907243127 1.1139418106635144 1.1455471506297366 0.9227294919338866 1.2394072525898716 0.9498681569102317 1.0024654413221221 1.0059855083958837 0.8308879626834226 0.9407492887417798 1.0 13.868013599779305 -6.753635280657588 1.2070749292915044 0.9273258323142637 1.0947071256576668 0.3462277123233026 0.09212645988896877 0.5000300356617766 1.5379757619669205 0.045200919928587845 0.04105430848386382 1.7634563706741836e-07 6.753635280657588 0.16738129334340313 QAPPHIELSNSS(ph)PDPMAEAER ddPTM_PC-9_Lapatinib_30min_R1 4 QAPPHIELSNSSPDPMAEAER 21 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 QAPPHIELSNS(0.19)S(0.81)PDPMAEAER;QAPPHIELSNS(0.277)S(0.723)PDPMAEAER;QAPPHIELSNS(0.238)S(0.762)PDPMAEAER;QAPPHIELSNS(0.031)S(0.969)PDPMAEAER 135.86 4.1055e-05 34025000.0 50582.7 44617.4 54002.2 47044.7 51577.3 52705.3 44726.2 48991.6 55770.3 38956.1 True False 49861.38142226891 44514.091151584864 49562.347570520215 50504.52417451865 48543.62461887332 50451.21718105508 47041.90378902264 51267.92858862888 49488.86152670539 45689.6099792596 1.091306786048361 0.9742716379455121 1.0847618877249907 1.1053831319077738 1.0624652878610537 1.1042164116515105 1.0295974032253044 1.1220916224039013 1.0831535123449385 1.0 15.47957850685419 QAPS(ph)IATIGSTCDLNLK ddPTM_PC-9_AZD4547_30min_R2 1 QAPSIATIGSTCDLNLK 17 0 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 1 QAPS(0.966)IAT(0.023)IGS(0.004)T(0.007)CDLNLK 159.26 2.9046999999999998e-05 4612400.0 12525.0 11779.0 20353.0 24198.0 17443.0 19177.0 18861.0 17475.0 15377.0 18244.0 True False 16507.68946381587 15586.331399100633 20083.10592158605 18619.52495537321 15021.34053809659 17977.85915844273 20539.59246140153 14774.64028555131 16189.796827232323 17605.283113041427 0.9376554388715002 0.885321258341752 1.1407431390131484 1.0576100841900387 0.8532291381880286 1.0211627409232238 1.1666720909581092 0.8392162847189166 0.9195987774396791 1.0 14.10372080711952 -7.822707183784349 24.999999439242064 0.9095560800882247 1.005593251608693 0.137492104295187 0.10133356390855597 143.2201361095786 58437.53860307336 0.05695852166942165 0.027361999442142376 1.504155777625726e-08 7.822707183784349 0.0960371715204682 QAPS(ph)IATIGSTCDLNLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QAPSIATIGSTCDLNLK 17 0 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 1 QAPS(0.985)IAT(0.015)IGSTCDLNLK 152.66 4.1789e-12 0.0 6842.7 6197.0 6603.6 9437.5 9038.4 9039.5 11238.0 10844.0 9219.8 6851.2 True False 8001.0339605145555 6812.197205453766 6761.054868292464 8908.747471787821 7267.390402697284 8565.452706869723 10173.455283925785 10559.356490167738 9354.622132852048 8093.268325930636 0.9886035700656849 0.8417115226030072 0.8353924021807367 1.1007601766080595 0.8979549558999226 1.0583428550646492 1.2570268121878871 1.304708563329825 1.1558522164500669 1.0 12.982506712336944 -7.01293588383929 3.5967558257279983 1.2032039735447728 0.9325426834082118 0.550802701815003 0.10384316638009315 0.16432173923597984 4.55490074573664 0.04037585459709471 0.03270022139411387 9.706532570387198e-08 7.01293588383929 -0.27066129013656104 QAQAQES(ph)EEEEESR ddPTM_PC-9_AZD4547_30min_R2 3 QAQAQESEEEEESR 14 0 H0YLQ7;Q9NVM6 H0YLQ7 DNAJC17 DnaJ homolog subfamily C member 17 1 QAQAQES(0.823)EEEEES(0.177)R;QAQAQES(1)EEEEESR;QAQAQES(1)EEEEESR 195.28 1.677e-47 7332800.0 16188.7 16469.870000000003 23137.9 27322.1 24828.800000000003 26598.300000000003 17518.0 27920.7 20045.0 19952.3 True False 21336.369854121833 21793.433391638126 22831.07632796471 21023.411967237065 21381.749696284623 24935.10409626154 19077.068063137263 23606.197368857935 21104.537777321435 19253.776050007476 1.1081654735520592 1.1319043773561324 1.18579733495736 1.0919111094173604 1.1105224056180045 1.2950760428239145 0.9908221646283174 1.226055466083432 1.0961246107001041 1.0 14.232853794415936 -8.536817383685152 22.94159686518699 0.999999995151235 1.1421555215630568 0.23947648887113904 0.07746989325464791 1055.5590993810433 1737345.0979836644 0.06951074058730318 0.017947596036420453 2.905244022569622e-09 8.536817383685152 0.14215552641182172 QAQAQES(ph)EEEEESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QAQAQESEEEEESR 14 0 H0YLQ7;Q9NVM6 H0YLQ7 DNAJC17 DnaJ homolog subfamily C member 17 1 QAQAQES(0.987)EEEEES(0.013)R;QAQAQES(1)EEEEESR;QAQAQES(1)EEEEESR 178.85 7.730599999999999e-19 11246500.0 17356.8 20606.6 19216.6 22601.8 26979.8 20229.0 25889.7 21148.1 19507.2 15196.0 True False 20294.963427573774 22652.287063724976 19674.79662336133 21335.494422024265 21693.301866114838 19168.155628880762 23437.24019080381 20592.98478326413 19792.455896003343 17950.914508530193 1.1305810307285291 1.2619015623388274 1.0960331081746255 1.1885463780625625 1.2084789248930063 1.067809421061648 1.3056293137414552 1.1471830459377677 1.1025876083693706 1.0 14.13176972350382 -8.534043993424078 2.219193075111696 1.001568817345798 1.1785953651899441 0.39520925781569727 0.06799327592143786 0.305720081167701 3.5053827595194464 0.06145942395971933 0.016934318437372135 2.9238561802964994e-09 8.534043993424078 0.17702654784414618 QAQAQES(ph)EEEEESR ddPTM_PC-9_Lapatinib_30min_R1 3 QAQAQESEEEEESR 14 0 H0YLQ7;Q9NVM6 H0YLQ7 DNAJC17 DnaJ homolog subfamily C member 17 1 QAQAQES(0.999)EEEEES(0.001)R;QAQAQES(1)EEEEESR;QAQAQES(0.968)EEEEES(0.032)R 117.08 0.00013526 6332200.0 15864.5 14272.5 16285.2 15027.8 15734.500000000002 16340.8 12202.599999999999 12975.8 20220.7 12674.78 True False 15638.269320807005 14239.452903149779 14946.293718689916 16132.994543271221 14809.02764521723 15641.942076265299 12834.390920219634 13578.703038486814 17943.231832589237 14865.59883491725 1.0519770844397374 0.9578795352463878 1.005428296879849 1.085256956173002 0.9961944896853303 1.0522241485169455 0.863361850588448 0.913431284489684 1.207030542923239 1.0 13.859689960438068 QAQEYEALLNIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QAQEYEALLNIK 12 0 P05783;F8VZY9;CON__P05784 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ; 147.71 0.00064219 27642000.0 81112.0 64212.0 70265.0 93248.0 80832.0 74074.0 84698.0 72806.0 65584.0 71621.0 False True 94842.65956497549 70586.54299767592 71940.3840814963 88023.61687409482 64993.54985736709 70189.42904017556 76674.79227958222 70894.91964433352 66543.0419272619 84605.32034847578 1.1210011282308694 0.8343038322760464 0.8503056756381911 1.0404028554178344 0.7681969595962648 0.8296101090460567 0.9062644283334785 0.8379487170821963 0.7865113169382464 1.0 16.36846076865139 -4.756675887014984 24.883135012748856 0.8685425060016139 1.121001536132445 0.44525008157503654 0.0830631903872891 126.0925255482272 658588.6786879953 0.020106353545648162 0.1591886394850143 1.7511530826510913e-05 4.756675887014984 0.25245903013083115 QAQEYEALLNIK ddPTM_PC-9_Lapatinib_30min_R1 2 QAQEYEALLNIK 12 0 P05783;F8VZY9;CON__P05784 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ; 202.65 3.4512e-06 223150000.0 519260.0 441020.0 579800.0 530450.0 492350.0 465700.0 473230.0 458480.0 480400.0 532740.0 False True 511855.2571793783 439998.845286188 532131.082092722 569461.0625293256 463390.9409973428 445783.0965997225 497731.5338678269 479782.65456352977 426292.29316373216 624823.3991685712 0.8191998856964778 0.7041971313361147 0.8516503748112004 0.91139522509414 0.7416350629857326 0.713454549226084 0.7965955412843683 0.7678692174492158 0.6822604494821787 1.0 19.253088956777695 -10.642621765425233 4.633305413792138 1.0000185301236937 0.7779873357121179 0.4971331899477066 0.06742820141918845 1.3439915035899185e-05 2.55333447373656e-06 0.06798467071579864 0.016487329124249078 2.2770797155467088e-11 10.642621765425233 -0.22203119441157582 QAQIEVVPS(ph)ASALIIK ddPTM_PC-9_AZD4547_30min_R2 1 QAQIEVVPSASALIIK 16 0 P30050 P30050 RPL12 60S ribosomal protein L12 1 QAQIEVVPS(0.5)AS(0.5)ALIIK 103.04 0.007809100000000001 0.0 18354.0 14301.0 19191.0 28165.0 22169.0 23904.0 16451.0 18839.0 17856.0 16571.0 True False 24190.190213083955 18923.518578702628 18936.51480082336 21671.99439491223 19091.217014794667 22409.279101184515 17915.10713019016 15927.865427153141 18799.831706253506 15990.854333819843 1.5127515833799408 1.183396345414788 1.1842090738562725 1.3552743300948635 1.1938834921670016 1.4013809789880975 1.1203345835188194 0.9960609417513432 1.175661494614007 1.0 13.964959398432697 -7.436015550843763 5.832197980528757 1.0629829290763309 1.2906146555208402 0.5229829574037987 0.10921643126318596 0.1901986179394682 10.090307077369006 0.04505706800880304 0.029824654186306622 3.664244538008299e-08 7.436015550843763 0.22763172644450935 QAQIEVVPS(ph)ASALIIK ddPTM_PC-9_Lapatinib_30min_R1 1 QAQIEVVPSASALIIK 16 0 P30050 P30050 RPL12 60S ribosomal protein L12 1 QAQIEVVPS(0.5)AS(0.5)ALIIK 86.22200000000001 0.022716 0.0 22271.0 15877.0 16031.0 14935.0 15351.0 16633.0 14242.0 12665.0 14568.0 12063.0 True False 21953.411455998805 15840.237781979964 14712.993061449544 16033.36972169949 14448.084361227204 15921.645363416765 14979.3810733588 13253.462135855629 12927.19843215912 14148.07347706286 1.5516891039327803 1.1196038674566169 1.0399290818854272 1.133254626341396 1.0212050696973498 1.1253578368269894 1.0587576533047889 0.936767974618057 0.9137073293489006 1.0 13.78831799625951 -2.353976563994834 1.186944302426382 1.0265590589610303 199.99356366502386 0.8446374002048603 0.06689469437008573 227.66988319574787 1.1435026053624873 0.02179334111235217 122397.29311437558 0.0044261225657872 2.353976563994834 198.96700460606283 QAQIEVVPSASALIIK ddPTM_PC-9_Lapatinib_30min_R1 2 QAQIEVVPSASALIIK 16 0 P30050 P30050 RPL12 60S ribosomal protein L12 0 ; 179.39 2.5784000000000003e-05 13519300.0 58839.0 51914.0 64775.0 58313.0 57081.0 62320.0 58670.0 58554.0 53729.0 64969.0 False True 57999.945070248905 51793.79632258665 59449.44953873081 62601.53254646552 53723.60780556381 59654.71887501546 61707.64552548522 61274.63260188634 47677.47422854737 76198.80508424899 0.7611660708605789 0.6797192720452898 0.7801887375136749 0.8215553049322796 0.7050452792030591 0.7828826030678354 0.8098243201748155 0.8041416467638596 0.6256984499406901 1.0 16.217480753743835 -10.878378725360095 3.3885487312795504 1.0015815153513836 0.7557065357626791 0.6035199088892296 0.06018405839927484 29553312.25680793 43829960.59681496 472411.65284938295 0.0151709671391397 1.3231871500563278e-11 10.878378725360095 -0.24587497958870452 QAQQERDELADEIANSS(ph)GK ddPTM_PC-9_AZD4547_30min_R2 2 QAQQERDELADEIANSSGK 19 1 P35579;P35579-2 P35579 MYH9 Myosin-9 1 QAQQERDELADEIANS(0.248)S(0.752)GK;QAQQERDELADEIANS(0.229)S(0.771)GK 146.6 7.138899999999999e-05 20869000.0 60000.0 70724.0 55340.0 61403.0 58349.0 75600.0 65125.0 76369.0 64079.0 63497.0 True False 79078.75192247129 93584.14991680063 54606.15544148634 47247.48701689317 50248.24852705373 70872.72004892708 70920.99883615786 64567.92583503675 67466.08512012873 61273.98935698258 1.2905761931340567 1.527306299114603 0.8911800262155382 0.7710855374803338 0.820058381286506 1.156652615451921 1.157440531951849 1.053757499921601 1.1010558611921115 1.0 15.902987163265086 -5.262797258734096 24.99835347009267 0.9933102071368508 1.4089412618156776 0.5960545134975508 0.13666691552763127 84.3101908489805 1552172.4404632703 0.04001064452449585 0.0912974560802145 5.46012696174446e-06 5.262797258734096 0.4156310546788268 QAQQERDELADEIANSS(ph)GK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QAQQERDELADEIANSSGK 19 1 P35579;P35579-2 P35579 MYH9 Myosin-9 1 QAQQERDELADEIANS(0.093)S(0.907)GK 68.676 0.0039059 6488700.0 12704.0 14634.0 12489.0 16656.0 14144.0 12954.0 15905.0 15814.0 14586.0 10122.0 True False 14854.536284562651 16086.766807263275 12786.78512479625 15722.818319480577 11372.584733553555 12274.669435786302 14398.3632577718 15398.899256318022 14799.292655999045 11957.038474292092 1.2423257076992975 1.3453805339717015 1.0693939935284253 1.3149425213680626 0.9511205268766905 1.0265643505435835 1.2041747033538959 1.2878522795946512 1.2377055311662553 1.0 13.54557248584752 -5.255696725371063 24.678553964999654 1.1449970033451058 1.2938531246872915 0.21211116938763452 0.12043690035144226 654.9326794369385 2814492.7313471437 0.03202082802147996 0.07984913413877526 5.550131520290712e-06 5.255696725371063 0.14885612134218573 QAQQERDELADEIANSS(ph)GK ddPTM_PC-9_Lapatinib_30min_R1 1 QAQQERDELADEIANSSGK 19 1 P35579;P35579-2 P35579 MYH9 Myosin-9 1 QAQQERDELADEIANS(0.051)S(0.949)GK 124.82 1.3100999999999999e-05 9583000.0 35583.0 51728.0 42627.0 40060.0 54269.0 46117.0 48835.0 47114.0 50021.0 34764.0 True False 35075.57989487696 51608.226994158846 39122.37260497842 43006.146036242506 51077.0041169591 44144.6834139777 51363.43734850981 49303.08843811311 44387.108235518404 40772.911079881735 0.8602667547126414 1.2657479102497418 0.9595187483260736 1.0547725167816802 1.2527190912831738 1.0826963845551776 1.259744177890052 1.2092118794637736 1.0886421170309812 1.0 15.315323344729553 -6.121506404692043 8.906755955558951 1.1614075121571126 1.0448582405441211 0.16770183839812614 0.12165181982611008 0.5645665011987953 38.72817193902706 0.03383732270561319 0.04375551357780224 7.559509119852278e-07 6.121506404692043 -0.11654927161299145 QAQQERDELADEIANSSGK ddPTM_PC-9_AZD4547_30min_R2 2 QAQQERDELADEIANSSGK 19 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 167.92 8.9631e-08 19327400.0 41134.0 40682.0 57013.0 76567.0 63318.0 51544.0 47579.0 60203.0 41843.0 58202.0 False True 54213.75635964889 53831.66092013006 56256.97036836759 58915.66109835778 54527.38864823711 48320.945531771016 51813.43882726384 50900.009677313064 44054.73555582244 56164.36569531004 0.9652696276097348 0.9584664627419665 1.001648815435038 1.048986494710426 0.9708538140365818 0.8603488160786976 0.922532253072173 0.9062687532775506 0.7843894435631664 1.0 15.777367461242124 -6.643899756803686 5.503764924851353 0.8909883242076054 0.9936453855008927 0.42311034087596455 0.0553869635450109 0.1982112155062313 8.78015366078399 0.01817275622710345 0.018104522239333516 2.2703888391309657e-07 6.643899756803686 0.10265706129328722 QAQQERDELADEIANSSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QAQQERDELADEIANSSGK 19 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 142.4 0.00027469 6377400.0 23880.0 18926.0 20264.0 30774.0 33008.0 30514.0 26455.0 26613.0 27178.0 24180.0 False True 27922.412348500966 20804.848202423444 20747.170611647958 29049.832550654126 26540.319349910606 28913.792123173014 23948.99088238624 25914.436948804323 27575.42683427547 28563.642591225307 0.9775508238952224 0.7283681741912935 0.7263489082453877 1.017021287039146 0.9291643831891293 1.0122585741937296 0.8384431644493171 0.9072525279659249 0.965403020507846 1.0 14.801892350975283 -5.762605647358435 24.999999974961057 0.9456561463179398 0.8025171899721426 0.38055100414842546 0.08249242534390244 31.9035729317792 683908.3434130515 0.022883921436603567 0.036205659863671684 1.7274057171669149e-06 5.762605647358435 -0.1431389563457972 QAQQERDELADEIANSSGK ddPTM_PC-9_Lapatinib_30min_R1 2 QAQQERDELADEIANSSGK 19 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 173.87 1.9406000000000002e-08 23531000.0 70005.0 60861.0 66485.0 57223.0 64486.0 64361.0 52359.0 57141.0 63475.0 54019.0 False True 69006.71586265518 60720.08009378871 61018.85993952171 61431.37031033212 60693.060264353946 61608.43006281888 55069.8928254454 59795.97946347624 56325.77707861758 63356.11217420699 1.0891879803626685 0.9583934053091813 0.963109285679357 0.9696202655462427 0.9579669298120663 0.9724149406992872 0.8692119976368278 0.9438075887462658 0.8890346194814092 1.0 15.95119618720366 -1.522878745431417 1.0159592352223796 0.9390847696338328 162.6867482280587 0.5596985512318795 0.03758136325715277 1228.8847134711934 1.5433536298021864 0.011723639373027903 462959.25995484256 0.029999999989563802 1.522878745431417 161.74766345842485 QAQS(ph)PAGVSSEVEVLK ddPTM_PC-9_AZD4547_30min_R2 2 QAQSPAGVSSEVEVLK 16 0 A0A2R8Y7R9;Q13136-2;Q13136;E9PJZ7 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 QAQS(0.973)PAGVS(0.014)S(0.014)EVEVLK;QAQS(1)PAGVSSEVEVLK 174.19 1.3217e-05 7531600.0 27583.0 23815.0 32890.0 42710.0 34591.0 33339.0 28212.0 33925.0 31313.0 33501.0 True False 36353.820237958724 31512.733022292356 32453.857110055767 32863.86936292213 29788.636734122534 31254.307059671628 30722.813346114206 28682.670768945805 32968.1412532435 32328.140186910783 1.124525568986424 0.9747771706041855 1.0038887768494609 1.0165716051994929 0.921446039329647 0.9667833311464686 0.9503427406737567 0.8872354117221696 1.0197970270678252 1.0 14.980502892262477 -1.5228788998701028 0.8996352524740232 0.9595008578899523 78.08144051252972 0.5387500798032895 0.04157156688566199 675.4482583651909 1.4848310587384264 0.013520052495444116 106948.52522880703 0.02999998932131923 1.5228788998701028 77.12193965463977 QAQSPAGVS(ph)SEVEVLK ddPTM_PC-9_Lapatinib_30min_R1 1 QAQSPAGVSSEVEVLK 16 0 A0A2R8Y7R9;Q13136-2;Q13136;E9PJZ7 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 QAQS(0.284)PAGVS(0.358)S(0.358)EVEVLK 82.65100000000001 0.0061845 3099000.0 16892.0 14403.0 14765.0 15988.0 20866.0 14690.0 13813.0 14890.0 17548.0 11719.0 True False 16651.11698238659 14369.650738417682 13551.078694548212 17163.81085440452 19638.702904134396 14061.742944062542 14528.169552471922 15581.843758617479 15571.55945136795 13744.613535414057 1.2114649087428833 1.04547506566068 0.9859192228019226 1.2487663483720832 1.4288290357188846 1.0230729956743692 1.0570082247157384 1.1336691074266771 1.1329208646897657 1.0 13.746578721949241 -10.71041056989491 6.556826968929021 0.9999993459235482 1.1389446271111578 0.10383290265540324 0.12397993030133388 1.2621944564402273e-06 1.5641859466189156e-07 0.12781276671753228 0.030999003298739856 1.9480021420770657e-11 10.71041056989491 0.13894528118760963 QAS(ph)DTEEDDITDNQK ddPTM_PC-9_Lapatinib_30min_R1 2 QASDTEEDDITDNQK 15 0 Q6ZU65-2;Q6ZU65;C9J6Y5;H7C4P8 Q6ZU65-2 UBN2 Ubinuclein-2 1 QAS(0.995)DT(0.005)EEDDITDNQK;QAS(0.81)DT(0.19)EEDDITDNQK 219.23 5.755599999999999e-63 3990700.0 28991.0 22099.4 31928.9 26921.9 24221.6 25762.3 23111.2 23608.1 25936.4 22018.7 True False 28577.583023701733 22048.23019708309 29303.829091118223 28901.82633482568 22796.93310949781 24660.506483854493 24307.784852029912 24705.01851160627 23015.169509599953 25824.60295692647 1.1066029968153637 0.8537684096773108 1.1347252517297108 1.1191585939590938 0.882760255695757 0.9549229672567047 0.9412646108276477 0.9566465959926825 0.8912109722649969 1.0 14.656458547943693 -6.267980479654431 24.98783322379977 0.9366625198275919 1.045089958827838 0.3336462630897278 0.07977804573497975 668.8505542123412 2555089.8197979783 0.024659991672983567 0.028578646864272098 5.395348725825619e-07 6.267980479654431 0.1084274390002461 QAS(ph)ESSSRPH ddPTM_PC-9_AZD4547_30min_R2 3 QASESSSRPH 10 1 A0A2R8Y653;Q9BZX2-2;Q9BZX2 A0A2R8Y653 UCK2 Uridine-cytidine kinase 2 1 QAS(0.983)ES(0.013)S(0.004)SRPH;QAS(0.981)ES(0.019)SSRPH;QAS(0.983)ES(0.017)SSRPH 99.73200000000001 0.0053068 20505590.0 9933.79 4501.75 6204.72 13413.93 9461.0 8867.8 8353.75 7334.6 12853.48 15140.289999999999 True False 13092.528584332096 5956.85265098067 6122.44135870797 10321.55568165259 8147.503458747459 8313.29506415177 9097.21756664191 6201.206102340756 13532.888711900503 14610.233055445608 0.8961204475415384 0.40771783915934173 0.41905158771070933 0.7064607143830249 0.5576573233176918 0.569004959236649 0.6226606743450368 0.4244426545974506 0.9262609747937217 1.0 13.834691571055265 -8.36611466084291 5.521476926612888 0.9902088515367458 0.570348748079568 0.5475724869658299 0.14129107218078316 0.16375824275030476 6.817457803701907 0.13013906067226366 0.03389693747569762 4.304129594319775e-09 8.36611466084291 -0.4198601034571777 QAS(ph)ESSSRPH ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QASESSSRPH 10 1 A0A2R8Y653;Q9BZX2-2;Q9BZX2 A0A2R8Y653 UCK2 Uridine-cytidine kinase 2 1 QAS(0.949)ES(0.006)S(0.041)S(0.004)RPH;QAS(0.999)ES(0.001)SSRPH;QAS(0.999)ES(0.001)SSRPH 101.39 0.0017085999999999998 18567010.0 2389.16 5214.650000000001 6736.5 6100.84 21132.3 29373.9 11907.099999999999 22423.800000000003 30989.100000000002 29639.1 True False 2793.597599939052 5732.3259895787505 6897.123708318514 5759.02971399015 16991.577514484856 27833.48097420436 10779.173288061273 21835.199009980024 31442.256961882627 35012.434207013495 0.07978872829640203 0.16372257797575476 0.19699069386432208 0.16448527057386184 0.4853012336708996 0.7949598936662597 0.30786700588507065 0.6236412721514267 0.8980311616147012 1.0 15.09557974683732 -7.095310906215952 0.35488964948468454 1.0168196209863167 1.3731533642794868e-15 0.7835646777957167 0.14958004039682862 0.7798507626214192 0.23086346258656554 0.19213708476497876 0.28812754130507073 8.02951093315156e-08 7.095310906215952 -1.0168196209863154 down QAS(ph)ESSSRPH ddPTM_PC-9_Lapatinib_30min_R1 6 QASESSSRPH 10 1 A0A2R8Y653;Q9BZX2-2;Q9BZX2 A0A2R8Y653 UCK2 Uridine-cytidine kinase 2 1 QAS(0.98)ES(0.019)S(0.001)SRPH;QAS(0.985)ES(0.004)S(0.009)S(0.003)RPH;QAS(0.999)ES(0.001)SSRPH;QAS(0.997)ES(0.003)SSRPH;QAS(0.897)ES(0.102)S(0.001)SRPH;QAS(0.912)ES(0.087)S(0.001)SRPH 94.538 0.0048958 53617980.0 3099.63 5036.799999999999 6953.75 7668.340000000001 14493.000000000002 9663.900000000001 20031.649999999998 20342.040000000005 26738.41 19493.950000000004 True False 3055.4287077974727 5025.137599060067 6382.039517251248 8232.295304432348 13640.550234334305 9250.597524651192 21068.79082138379 21287.205440668058 23726.848697860245 22863.4532834444 0.13363811100267745 0.2197890903339089 0.27913716437020175 0.3600635128199735 0.5966093601534608 0.4046019387346714 0.9215051882228072 0.9310581904126567 1.03776312369405 1.0 14.480755703427263 -6.953905630256723 0.6636945059245457 1.0721552758676418 0.17218307745714795 0.9176302625931697 0.09622156381773671 0.1941841552728213 0.18177212756770644 0.0778657318317141 0.06819334270870964 1.1119733265684509e-07 6.953905630256723 -0.8999721984104938 down QAS(ph)FLEAEGGAK ddPTM_PC-9_AZD4547_30min_R2 1 QASFLEAEGGAK 12 0 Q8WYP3;Q8WYP3-2 Q8WYP3 RIN2 Ras and Rab interactor 2 1 QAS(1)FLEAEGGAK 109.83 0.0012649 3106100.0 18333.0 23092.0 19968.0 22179.0 22720.0 22632.0 16939.0 22427.0 22372.0 22262.0 True False 24162.512649911092 30556.037411327936 19703.21127314058 17065.974212134166 19565.720175746992 21216.817462266044 18446.53818480889 18961.42247119081 23554.53824665678 21482.61415602543 1.1247473177343275 1.4223612261246892 0.9171700953170188 0.7944086361271593 0.9107699851444389 0.9876273580194227 0.8586728808158116 0.8826403683218657 1.0964465532724852 1.0 14.390881940864283 -5.276732714651321 24.86742010501291 0.9206187972064748 1.2735542606225887 0.6352931909353201 0.10359127003509748 369.4492841447016 600735.4687469904 0.026104979350291865 0.05466509664262278 5.287705820586982e-06 5.276732714651321 0.3529354634161139 QAS(ph)LDGLQQLR ddPTM_PC-9_Lapatinib_30min_R1 1 QASLDGLQQLR 11 0 Q3MII6 Q3MII6 TBC1D25 TBC1 domain family member 25 1 QAS(1)LDGLQQLR 91.712 0.008043000000000002 10151000.0 23972.0 22184.0 36909.0 20426.0 33065.0 50105.0 29743.0 23909.0 73283.0 28212.0 True False 23630.154884073592 22132.63431098089 33874.48449286015 21928.196179138515 31120.181708291166 47962.12595045977 31282.947006383307 25019.899424095736 65029.09683579889 33088.406609872975 0.7141520944989471 0.6688939292826787 1.0237568974612585 0.6627153866211116 0.940516177621121 1.44951452380148 0.9454352811612587 0.7561530453578945 1.965313639986381 1.0 15.014038199112171 -6.535669208980914 15.433554506095744 1.191172910325932 0.7815234529305664 0.30700079588838836 0.32283545852224593 3.4356307884950863 4141.374330738813 0.10345217963405945 0.10392964139880827 2.9129349815209715e-07 6.535669208980914 -0.40964945739536573 QAS(ph)LPVSGSVAGDFVK ddPTM_PC-9_AZD4547_30min_R2 1 QASLPVSGSVAGDFVK 16 0 F8W9F9;H0Y7T5;Q9Y3S1-2;Q9Y3S1-4;Q9Y3S1;H0Y7R3;H0Y7J9;H0Y493;E9PCD1 F8W9F9 WNK2 Serine/threonine-protein kinase WNK2 1 QAS(0.674)LPVS(0.326)GSVAGDFVK 179.84 4.9426e-06 18104000.0 32163.0 31129.0 39551.0 57526.0 51349.0 33138.0 39669.0 58999.0 36863.0 36904.0 True False 42390.16496804072 41190.84048922691 39026.527897835695 44264.26946784026 44220.07769825842 31065.875621446274 43199.46415096428 49882.060212145465 38811.50292269396 35612.00219270336 1.1903336616306892 1.1566561258290222 1.0958813179516187 1.2429593042345057 1.2417183807575636 0.872342853775614 1.213059123078891 1.400709231180659 1.089843326210009 1.0 15.12007592932742 -8.524111164118537 24.854693696033316 0.9999999748071393 1.1735671747508616 0.16560064153069742 0.126471840679338 211.22873885237365 4259956.646857064 0.12551536801552085 0.0324079286238178 2.991498820077837e-09 8.524111164118537 0.17356719994372227 QAS(ph)LPVSGSVAGDFVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QASLPVSGSVAGDFVK 16 0 F8W9F9;H0Y7T5;Q9Y3S1-2;Q9Y3S1-4;Q9Y3S1;H0Y7R3;H0Y7J9;H0Y493;E9PCD1 F8W9F9 WNK2 Serine/threonine-protein kinase WNK2 1 QAS(0.971)LPVS(0.029)GSVAGDFVK 142.4 2.6276e-05 11098000.0 25996.0 24477.0 20788.0 27031.0 33785.0 23535.0 24803.0 28294.0 20244.0 17223.0 True False 30396.609355595956 26906.91479714249 21283.664758929026 25516.540705684416 27165.071777651774 22300.783169000366 22453.480281830492 27551.31247997104 20540.030202114696 20345.393562807018 1.4940290666661447 1.3225064786326104 1.0461171317834441 1.2541679583102616 1.3351951975660803 1.0961096967801083 1.103614939298949 1.35417938192835 1.009566619525291 1.0 14.312414567831224 -4.966136710010499 3.7429576899366745 1.1691651502676175 1.4826628219653508 0.43998480768318593 0.12215361317974749 0.21354050203595093 6.219282125758623 0.030174389036571613 0.14251709246129957 1.0810935841370008e-05 4.966136710010499 0.31349767169773335 QAS(ph)LPVSGSVAGDFVK ddPTM_PC-9_Lapatinib_30min_R1 2 QASLPVSGSVAGDFVK 16 0 F8W9F9;H0Y7T5;Q9Y3S1-2;Q9Y3S1-4;Q9Y3S1;H0Y7R3;H0Y7J9;H0Y493;E9PCD1 F8W9F9 WNK2 Serine/threonine-protein kinase WNK2 1 QAS(0.91)LPVS(0.089)GS(0.001)VAGDFVK;QAS(0.938)LPVS(0.062)GS(0.001)VAGDFVK 202.61 4.2511000000000004e-13 29048000.0 83612.0 77565.0 82214.0 63189.0 69224.0 73757.0 75580.0 69508.0 72374.0 83049.0 True False 82419.67754743708 77385.40300807937 75454.6822752174 67836.12985232468 65152.38041962037 70602.58504596466 79493.16258421972 72737.59543142929 64222.47798799324 97403.90899416366 0.8461639619861209 0.7944794393489508 0.7746576400721101 0.6964415550960008 0.6688887652704393 0.7248434459667845 0.8161188129419207 0.746762590768176 0.6593418955274308 1.0 16.57169205096725 -10.369173438565596 7.654103622100826 1.0000000003733984 0.7472143108940642 0.6247337755169355 0.058703472978637185 4.3665085197336467e-10 0.0 0.06076987348526463 0.01473885924912754 4.273921699868708e-11 10.369173438565596 -0.2527856894793342 QAS(ph)PAWK ddPTM_PC-9_AZD4547_30min_R2 2 QASPAWK 7 0 A0A2R8Y7W8;A0A2R8Y6W5;Q16626 A0A2R8Y7W8 MEA1 Male-enhanced antigen 1 1 QAS(1)PAWK;QAS(1)PAWK 89.029 0.016874 8957900.0 99032.0 96456.0 121394.0 154862.0 132386.0 115989.0 109446.0 137499.0 101621.0 128155.0 True False 130522.11600643647 127633.5157001147 119784.23624256946 119160.95849404928 114006.4890486992 108736.18949411348 119186.4819750043 116251.68896269046 106992.47859661683 123668.33245734642 1.0554206837991766 1.0320630444672316 0.9685926369540351 0.9635527230477394 0.9218729385553927 0.8792565350682392 0.9637591096015795 0.9400279493764988 0.8651566368740263 1.0 16.916116593540984 -5.328454409732291 1.189965695425038 0.9256910934902606 1.0694705662763782 0.5909789114253485 0.03693656965785198 0.4802380018435838 1.0390079730128485 0.01182527012802274 0.06762129144201166 4.69402707501133e-06 5.328454409732291 0.14377947278611758 QAS(ph)PAWK ddPTM_PC-9_Lapatinib_30min_R1 2 QASPAWK 7 0 A0A2R8Y7W8;A0A2R8Y6W5;Q16626 A0A2R8Y7W8 MEA1 Male-enhanced antigen 1 1 QAS(1)PAWK;QAS(1)PAWK 74.533 0.034042 10659000.0 147057.0 117304.0 141701.0 136114.0 128817.0 121053.0 125055.0 102039.0 132295.0 104723.0 True False 144959.94021304935 117032.38979513604 130050.89076167773 146124.27762299354 121240.23732396628 115875.84537832571 131529.7360011856 106780.10445168384 117394.54397188978 122824.23101537357 1.1802226565123384 0.9528444739905387 1.0588374108802652 1.1897023609673858 0.9871035733070536 0.943428217871943 1.0708777487458674 0.8693732789445958 0.955793030425697 1.0 16.906235681050433 -6.495232448312702 23.884321253236887 0.9660666346357131 1.0833318172539046 0.37842176070345523 0.07773927116686491 479.46929102661807 414225.57856219343 0.024103135671967015 0.027250825120659815 3.197183416718273e-07 6.495232448312702 0.11726518261819152 QAS(ph)PTEVVER ddPTM_PC-9_AZD4547_30min_R2 1 QASPTEVVER 10 0 Q8TB72-4;A0A0A0MR59;Q8TB72-3;Q8TB72;C9JW01;Q8TB72-2;A0A0C4DG68 Q8TB72-4 PUM2 Pumilio homolog 2 1 QAS(0.851)PT(0.149)EVVER 73.36 0.028158999999999997 10591000.0 31748.0 33250.0 31821.0 44247.0 39619.0 41916.0 33307.0 43288.0 41145.0 37011.0 True False 41843.20360057693 43997.41226081127 31399.032748527963 34046.537759335435 34118.585723720076 39294.98589379389 36271.25847579135 36598.83425928156 43319.8407008177 35715.25615527163 1.1715778662951242 1.2318940698488363 0.8791490284157857 0.9532771544831861 0.9552944426715002 1.1002297092021245 1.0155676419651734 1.0247395146815856 1.2129225816688878 1.0 15.124252848145122 -5.238288090765808 24.96350812417989 1.0168803044074766 1.2017360129020884 0.4216849402706052 0.08622949315324674 763.4122236101273 823167.2227996662 0.02266267969512588 0.05987682848913738 5.7771269253168575e-06 5.238288090765808 0.18485570849461186 QAS(ph)PTEVVER ddPTM_PC-9_Lapatinib_30min_R1 2 QASPTEVVER 10 0 Q8TB72-4;A0A0A0MR59;Q8TB72-3;Q8TB72;C9JW01;Q8TB72-2;A0A0C4DG68 Q8TB72-4 PUM2 Pumilio homolog 2 1 QAS(0.857)PT(0.143)EVVER;QAS(0.511)PT(0.489)EVVER 142.39 0.00012679 110026000.0 187062.0 144580.0 181962.0 150221.0 177709.0 183739.0 148078.0 143044.0 181516.0 148371.0 True False 184394.46157703063 144245.23389296865 167001.7867536323 161268.75346256574 167256.5060093365 175880.9112865288 155744.75428878126 149690.3464477954 161071.75663178164 174016.7296580694 1.0596364035765569 0.8289158989276512 0.9596881120670353 0.926742812483877 0.9611518750983525 1.010712657525069 0.8949987429071257 0.8602066407173975 0.9256107556341064 1.0 17.408866485306845 QAS(ph)SDSDSILSLK ddPTM_PC-9_AZD4547_30min_R2 2 QASSDSDSILSLK 13 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 QAS(0.971)S(0.028)DS(0.001)DSILSLK;QAS(0.975)S(0.024)DS(0.001)DSILSLK 107.5 0.0018308 2300400.0 29128.0 17669.4 26400.0 41808.0 35470.0 32019.0 28993.0 44737.0 29866.0 29169.0 True False 38390.098099962386 23380.688006050503 26049.918750546425 32169.811527161055 30545.602756766984 30016.84686834116 31573.320833116708 37823.924603989086 31444.65578735255 28147.802188352623 1.363875511241441 0.830639914604959 0.9254690144627246 1.1428889300803995 1.0851860671881002 1.0664010876402257 1.1216975528619262 1.3437612056134307 1.1171265016337277 1.0 14.780734659021919 -7.522989905140956 24.999999098620943 1.184812182124067 1.0589859959592456 0.04596276208924943 0.15320220282072247 8.86683989394898 1992431.2831160717 0.06991820642677926 0.04086687501193227 2.999232233147092e-08 7.522989905140956 -0.12582618616482133 QAS(ph)TDAGTAGALTPQHVR ddPTM_PC-9_AZD4547_30min_R2 3 QASTDAGTAGALTPQHVR 18 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 QAS(0.758)T(0.242)DAGTAGALTPQHVR;QAS(0.73)T(0.27)DAGTAGALTPQHVR;QAS(0.5)T(0.5)DAGTAGALTPQHVR 123.54 2.6181e-05 237198000.0 110946.0 75923.7 80007.1 145312.0 144610.0 111531.0 62254.4 130993.0 107263.1 97272.0 True False 146224.52017984146 100464.55125612517 78946.15357828957 111812.5634480201 124533.39765029793 104556.9489388477 67794.92099724687 110751.04176968372 112932.80848404116 93866.53688729243 1.5577917863893966 1.0702914434433126 0.841046833048522 1.1911866268409992 1.3267070649450705 1.1138894903983885 0.7222480262444292 1.1798777865072927 1.2031210719922694 1.0 16.51832331302976 -7.006742888607092 24.847302422990094 1.0236968628060965 1.1752096420472706 0.12450455261352866 0.20982538259692418 744.4597941814656 2743312.860916705 0.07919392146636582 0.067254687124253 9.845938333391775e-08 7.006742888607092 0.15151277924117412 QAS(ph)TDAGTAGALTPQHVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 QASTDAGTAGALTPQHVR 18 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 QAS(0.763)T(0.237)DAGTAGALTPQHVR;QAS(0.735)T(0.265)DAGTAGALTPQHVR;QAS(0.751)T(0.24)DAGT(0.008)AGALT(0.001)PQHVR;QAS(0.987)T(0.013)DAGTAGALTPQHVR;QAS(0.5)T(0.5)DAGTAGALTPQHVR 173.09 3.1296e-08 146126000.0 110613.0 108410.0 132441.0 123803.0 125669.0 100171.0 104980.0 104473.0 87908.0 80235.0 True False 129337.59619366558 119172.22834326964 135598.89572528968 116866.71928474124 101045.06157246475 94917.85641903283 95035.53441061807 101730.69444829332 89193.48819440299 94780.97036008925 1.3645945562942619 1.2573434086031594 1.4306552803809256 1.2330188100073718 1.0660901781082968 1.0014442356775155 1.002685813930388 1.0733240444975491 0.9410484810984899 1.0 16.532309810793464 -6.198571206157956 2.492603819802471 1.010019936382942 1.3419433909219571 0.8989241644345689 0.05169563273865212 0.08193868319014448 1.00010409366979 0.015917512867639837 0.021095517888978055 6.330365616424761e-07 6.198571206157956 0.33192345453901506 QAS(ph)TDAGTAGALTPQHVR ddPTM_PC-9_Lapatinib_30min_R1 3 QASTDAGTAGALTPQHVR 18 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 QAS(0.738)T(0.262)DAGTAGALTPQHVR;QAS(0.462)T(0.462)DAGT(0.077)AGALTPQHVR;QAS(0.5)T(0.5)DAGTAGALTPQHVR 218.25 1.1482e-27 245965000.0 71552.0 68907.0 101512.0 78888.0 53413.0 63099.0 51305.0 80768.0 85540.0 50555.0 True False 70531.65535897034 68747.4500751333 93166.07520765188 84689.68668265326 50271.35235399836 60400.40286095316 53961.321862707046 84520.77613808039 75905.5844238669 59293.364389696806 1.189537076955383 1.1594459309696261 1.5712732135645353 1.4283164322746624 0.8478411179975787 1.0186705288635758 0.9100735372014699 1.4254677063453538 1.2801699685143306 1.0 15.855583039165058 -6.236348835262259 24.954819398951923 1.0900439780569415 1.341174088103129 0.2990264340245936 0.192215766228906 1113.669768439815 1107645.4557677372 0.0620293919279275 0.08004480937823938 5.802981215511607e-07 6.236348835262259 0.25113011004618757 QASASYDS(ph)EEEEEGLPMSYDEKR ddPTM_PC-9_Lapatinib_30min_R1 4 QASASYDSEEEEEGLPMSYDEKR 23 1 Q15059 Q15059 BRD3 Bromodomain-containing protein 3 1 QAS(0.24)AS(0.128)Y(0.023)DS(0.608)EEEEEGLPMSYDEKR;QAS(0.063)AS(0.118)Y(0.003)DS(0.816)EEEEEGLPMSYDEKR;QAS(0.029)AS(0.054)Y(0.03)DS(0.886)EEEEEGLPMSYDEKR;QAS(0.004)AS(0.012)Y(0.038)DS(0.946)EEEEEGLPMSYDEKR 80.41199999999999 8.3836e-05 20624900.0 167550.0 106381.0 131657.0 106208.0 118854.0 115060.2 89745.0 87892.4 133834.0 84818.5 True False 165160.7062750927 106134.68133052922 120832.66967071682 114018.8906195017 111863.2413959545 110139.34346442638 94391.55697434238 91976.20177098119 118760.20558550148 99479.26471145314 1.6602525838339615 1.0669025513847594 1.2146518173531016 1.1461573519890984 1.124488019894618 1.1071588012224816 0.948856600902027 0.9245766144107003 1.1938186910606357 1.0 16.60210822364367 -2.8007480857632294 1.4692038960140312 1.0721915000587259 199.99999999850695 0.753547876213664 0.09783235671781218 241.76923274996378 2.023467496776317 0.02870790194688543 160698.82061989658 0.0015821655145341258 2.8007480857632294 198.92780849844823 QASEGPLK ddPTM_PC-9_AZD4547_30min_R2 2 QASEGPLK 8 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 107.01 0.017586 23770500.0 68858.0 80776.0 108928.0 127854.0 110258.0 98666.0 92053.0 108363.0 87478.0 103590.0 False True 90753.41166462547 106885.2623392268 107483.54354770907 98379.23562460892 94950.5798916156 92496.39942258471 100245.53866970957 91617.9882840169 92101.90849012339 99963.34563034198 0.9078668895319465 1.0692445482415287 1.07522955409252 0.9841530913581964 0.9498539618985617 0.9253031582659352 1.0028229651337512 0.916515825938983 0.9213568024294657 1.0 16.60911156672367 -5.993340423125482 7.2889614630251955 0.9510541507695827 1.0239488114735318 0.24306221743889755 0.05096670753497009 0.16880637645810326 55.7409570810807 0.01451551635177115 0.020818403751029828 1.0154524151897004e-06 5.993340423125482 0.07289466070394912 QASEGPLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QASEGPLK 8 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 104.44 0.017776 30961000.0 128587.0 153383.0 150631.0 158519.0 197100.0 150079.0 154056.0 133474.0 128983.0 144272.0 False True 150354.23939098392 168609.85056706713 154222.61431124856 149637.69435553177 158479.6698941888 142208.59304101998 139462.70041114723 129970.44892739278 130869.13236313761 170427.37154347627 0.8822188480013513 0.9893355101357912 0.9049169327352218 0.8780144468598988 0.9298956409344165 0.8344234365237649 0.8183116312133588 0.7626148766498879 0.767887993448005 1.0 17.378797533115645 -6.827698831815048 4.788196561079521 0.8187960723652217 0.918185337825984 0.23763432611380841 0.06852848354115765 0.2463451223850941 10.905285809375274 0.02360843013196366 0.02106906561784211 1.4869664445732072e-07 6.827698831815048 0.09938926546076232 QASEGPLK ddPTM_PC-9_Lapatinib_30min_R1 4 QASEGPLK 8 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ;;; 117.04 0.016422 277674000.0 358247.0 339798.0 345586.0 342325.0 329494.0 320410.0 330076.0 307700.0 305009.0 318757.0 False True 353138.33208554634 339011.218608127 317173.25308053754 367500.72246272344 310113.81073012814 306706.81121219037 347165.7202057283 321996.865314077 270655.6745328409 373853.7227329964 0.9445895830700478 0.9068017729764491 0.8483886445262453 0.9830067219236701 0.8295057448220441 0.8203925561314743 0.9286137842036992 0.8612910497725466 0.7239614268229214 1.0 18.512114373513043 -6.293121302385267 24.961480277672763 0.8550795538845553 0.9145393689164022 0.13036795365773768 0.07451413335458638 1376.4736434872411 1084489.1465636876 0.022499750306729804 0.025514204914625166 5.091886301938091e-07 6.293121302385267 0.05945981503184694 QASGT(ph)PQPALR ddPTM_PC-9_AZD4547_30min_R2 1 QASGTPQPALR 11 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 QAS(0.012)GT(0.988)PQPALR 81.789 0.035858999999999995 12277000.0 14389.0 13618.0 20384.0 29765.0 23689.0 23226.0 19824.0 30572.0 21826.0 22908.0 True False 18964.402690207316 18019.752185495585 20113.694841331 22903.139114665824 20400.1912519045 21773.67454836477 21588.297595823336 25847.799874670945 22979.67780133788 22105.99789265253 0.8578849406527177 0.815152171505675 0.9098750003959911 1.0360599519589317 0.922835121534369 0.984966824573967 0.9765810030678931 1.169266368348931 1.039522301274431 1.0 14.432150240386859 -5.532226012698865 0.49242004497516695 1.0616875364202523 0.7549394105872118 0.5840171263480551 0.06201222632335403 1.6611566987297095 0.524556805286812 0.04730043806989884 0.2735671392990056 2.9361212572419817e-06 5.532226012698865 -0.30674812583304045 QASGT(ph)PQPALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QASGTPQPALR 11 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 QAS(0.005)GT(0.995)PQPALR 84.17299999999999 0.029713999999999997 11427000.0 18849.0 18926.0 17555.0 22362.0 25243.0 23419.0 21769.0 28110.0 22277.0 19582.0 True False 22039.763415280355 20804.848202423444 17973.577777708237 21109.129638582173 20296.815358391697 22190.866413206695 19706.8827260883 27372.14228500694 22602.75898105656 23132.0615889733 0.9527799037931998 0.8993944669566674 0.7769985268531346 0.9125485663000557 0.8774321856408543 0.9593120927788269 0.8519293730171577 1.1832988676657692 0.9771182258926263 1.0 14.497606227955375 -7.742235753120993 24.99990000825223 1.06015646201821 0.8891104077940668 0.5310239765288226 0.07028750390606454 164.39792508805112 214019.00869982314 0.03192501954020804 0.018395819168657148 1.8103570886575565e-08 7.742235753120993 -0.1710460542241432 QASGT(ph)PQPALR ddPTM_PC-9_Lapatinib_30min_R1 1 QASGTPQPALR 11 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 QAS(0.01)GT(0.99)PQPALR 97.20299999999999 0.013418000000000001 7588900.0 32538.0 23073.0 27679.0 23230.0 24029.0 26713.0 21650.0 18392.0 30126.0 19716.0 True False 32074.002153261576 23019.575886100887 25403.339464029792 24938.4116930083 22615.66146283165 25570.54726104443 22770.931065736422 19246.55946329702 26732.89263915609 23123.884330081342 1.387050795420959 0.9954891469576864 1.0985757886266174 1.078469833918278 0.9780217345842472 1.1058067449239175 0.9847364197421723 0.8323238080835581 1.1560727539351972 1.0 14.497096140409223 -4.758709857277059 24.995467626204476 1.023950703737048 1.38705128128871 0.6123934481009805 0.08628423932214793 49.82556128878955 456187.30291121936 0.02117442978002433 0.14191556327693555 1.7429709255773577e-05 4.758709857277059 0.3631005775516618 QASLPVS(ph)GSVAGDFVK ddPTM_PC-9_AZD4547_30min_R2 1 QASLPVSGSVAGDFVK 16 0 F8W9F9;H0Y7T5;Q9Y3S1-2;Q9Y3S1-4;Q9Y3S1;H0Y7R3;H0Y7J9;H0Y493;E9PCD1 F8W9F9 WNK2 Serine/threonine-protein kinase WNK2 1 QAS(0.282)LPVS(0.674)GS(0.044)VAGDFVK 170.0 3.1135e-05 16367000.0 19240.0 22426.0 25971.0 36872.0 32477.0 29818.0 22464.0 36638.0 25830.0 26314.0 True False 25357.919783139096 29674.76593566781 25626.607570850047 28371.730066721248 27968.129143826365 27953.475746281787 24463.25248146566 30976.438957483777 27195.32106700988 25392.754869358236 0.9986281486038691 1.168631213444144 1.0092094261806153 1.11731595144715 1.1014216176117175 1.1008445475923374 0.9633949765326874 1.2198928047331896 1.0709874216848692 1.0 14.63212930154391 QASLPVS(ph)GSVAGDFVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QASLPVSGSVAGDFVK 16 0 F8W9F9;H0Y7T5;Q9Y3S1-2;Q9Y3S1-4;Q9Y3S1;H0Y7R3;H0Y7J9;H0Y493;E9PCD1 F8W9F9 WNK2 Serine/threonine-protein kinase WNK2 1 QAS(0.189)LPVS(0.628)GS(0.183)VAGDFVK 103.77 0.0013189 12991000.0 31759.0 26688.0 24433.0 33177.0 39518.0 30402.0 33686.0 25690.0 18580.0 23557.0 True False 37135.17143115756 29337.40826515251 25015.575382668503 31318.200251285263 31774.731582336633 28807.665600337754 30495.018214479787 25015.66472080497 18851.6973500934 27827.697622890613 1.334467979866605 1.0542520859152944 0.8989452063792405 1.125432677747778 1.1418383228441886 1.0352155607958393 1.0958512855693487 0.898948416782691 0.6774436608289972 1.0 14.76423392905818 -7.853754766403558 4.04669055685051 0.8245139216196252 1.0894281644937513 0.433532997243809 0.12564178376125854 0.20344391914013463 6.132145920585078 0.07342019819450807 0.033395432761568686 1.4003778524321332e-08 7.853754766403558 0.2649142428741261 QASPT(ph)EVVER ddPTM_PC-9_AZD4547_30min_R2 2 QASPTEVVER 10 0 Q8TB72-4;A0A0A0MR59;Q8TB72-3;Q8TB72;C9JW01;Q8TB72-2;A0A0C4DG68 Q8TB72-4 PUM2 Pumilio homolog 2 1 QAS(0.074)PT(0.926)EVVER;QAS(0.033)PT(0.967)EVVER 153.0 0.00042185 203407000.0 142759.0 152691.0 196831.0 267150.0 220070.0 189647.0 147022.0 199216.0 148640.0 189219.0 True False 188153.39242833434 202045.37971475293 194220.89233290925 205562.69492635582 189517.07918471098 177788.34311003736 160106.6731806467 168431.7447282626 156496.8069454257 182594.50040378072 1.030443918147923 1.1065250008513918 1.0636732864539649 1.125787986340138 1.0379123071375205 0.9736785210774954 0.876842800996714 0.9224360227487723 0.857072949072158 1.0 17.478283787624896 -6.82994012530471 2.314551699130799 0.9082274954555096 1.081779080500584 0.7539007015508157 0.04321637869820826 0.13036506629455705 1.4296129724097013 0.015998883815421076 0.014141993569543322 1.479312321841845e-07 6.82994012530471 0.1735515850450744 QASPT(ph)EVVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QASPTEVVER 10 0 Q8TB72-4;A0A0A0MR59;Q8TB72-3;Q8TB72;C9JW01;Q8TB72-2;A0A0C4DG68 Q8TB72-4 PUM2 Pumilio homolog 2 1 QAS(0.407)PT(0.593)EVVER 109.95 0.0044238 71113000.0 27453.0 24173.0 29799.0 33496.0 38121.0 31115.0 29381.0 26874.0 31614.0 20704.0 True False 32100.25067853419 26572.73568620849 30509.52117333683 31619.327715497224 30651.463703888236 29483.274625172995 26597.81897998072 26168.585975356673 32076.294942188004 24457.47130722618 1.3124926234320013 1.0864874521331784 1.247451986760484 1.29282898130826 1.2532556337838567 1.2054915348694244 1.087513040324907 1.0699628611084142 1.3115131380205596 1.0 14.577987628831305 -7.106873814506894 4.8780379450378994 1.123762284072674 1.2332617905397578 0.2733913213065401 0.0931840736781896 0.34515327996143713 12.722870051399983 0.035606926507715006 0.027516736184140758 7.818549417592394e-08 7.106873814506894 0.10949950646708384 QASPT(ph)EVVER ddPTM_PC-9_Lapatinib_30min_R1 2 QASPTEVVER 10 0 Q8TB72-4;A0A0A0MR59;Q8TB72-3;Q8TB72;C9JW01;Q8TB72-2;A0A0C4DG68 Q8TB72-4 PUM2 Pumilio homolog 2 1 QAS(0.058)PT(0.942)EVVER;QAS(0.407)PT(0.593)EVVER 113.52 0.003166 105613000.0 183007.0 154802.0 182133.0 154076.0 167687.0 172816.0 141275.0 130451.0 159116.0 133124.0 True False 180397.28662062628 154443.56548000686 167158.72779371144 165407.26302246834 157823.98034532656 165425.06253377217 148589.528236116 136512.22969478925 141194.68051423886 156134.30602342004 1.1553981390455395 0.9891712424612207 1.0706085808498598 1.0593909002782347 1.0108219286647553 1.059504901561855 0.9516776422846345 0.8743256570039931 0.9043155480068535 1.0 17.25242803732673 -7.358721821640781 3.6645629806304996 0.9162652440514345 1.0533046476743821 0.5906440132395929 0.05084593578536362 0.1596429420305335 3.9675112787343476 0.02167016325372289 0.01407854853178216 4.3780244067685235e-08 7.358721821640781 0.13703940362294764 QAST(ph)DAGTAGALTPQHVR ddPTM_PC-9_AZD4547_30min_R2 1 QASTDAGTAGALTPQHVR 18 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 QAS(0.306)T(0.694)DAGTAGALTPQHVR 163.0 1.9413e-06 53984000.0 30807.0 21291.0 29784.0 47111.0 47322.0 32888.0 30820.0 36681.0 27610.0 35644.0 True False 40602.985174592875 28172.899381802497 29389.04469948011 36250.28680769435 40752.15713717864 30831.508160967052 33562.920293748735 31012.794295525473 29069.40823306785 34396.11440918924 1.1804526724025959 0.8190721500297093 0.8544292052833896 1.0539064493287575 1.1847895565288422 0.8963660195504563 0.9757765047083948 0.9016365606470979 0.8451363978863172 1.0 15.069957978220728 -10.517771724220992 4.866157666445212 1.0000004458061775 0.9653139116223223 0.005379028256681795 0.12623219529102644 31910945.819873102 68972721.32369775 88.2123921639143 0.031095325073237416 3.0354862906220395e-11 10.517771724220992 -0.034686534183855255 QAST(ph)DAGTAGALTPQHVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QASTDAGTAGALTPQHVR 18 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 QAS(0.28)T(0.506)DAGT(0.204)AGALT(0.01)PQHVR 106.31 0.00078763 12238000.0 10501.0 10960.0 10452.0 8781.6 10929.0 7916.2 7308.8 8475.8 7774.8 6899.7 True False 12278.611895796012 12048.03636788338 10701.215319430736 8289.595422331337 8787.540904482945 7501.06053632635 6616.457552870325 8253.319230852429 7888.491741523481 8150.560992004851 1.5064744510028818 1.4781849224491037 1.3129421802901549 1.017058265125906 1.078151665032987 0.9203121777365243 0.8117794050447108 1.0126075050476129 0.9678464769801193 1.0 12.992683646156703 -5.627788795748103 1.398157827658615 0.9476458197104021 1.5324339221079446 0.9167879990635313 0.06516352481560601 0.1217908897157882 0.4598872307108552 0.022115675232858227 0.06396498606916051 2.3561948600163287e-06 5.627788795748103 0.5847881023975425 QAST(ph)DAGTAGALTPQHVR ddPTM_PC-9_Lapatinib_30min_R1 1 QASTDAGTAGALTPQHVR 18 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 QAS(0.263)T(0.737)DAGTAGALTPQHVR 112.42 0.00037536 44427000.0 42094.0 29300.0 39280.0 30269.0 28671.0 29554.0 28815.0 20416.0 32333.0 29700.0 True False 41493.7318409058 29232.157650186622 36050.55002518483 32495.083234423953 26984.628149354805 28290.044313738894 30306.89970712219 21364.60189227229 28691.317058415774 34833.60542723757 1.1911983078404067 0.8391941428873456 1.0349359356581471 0.932865915998892 0.7746722688732822 0.8121480382739237 0.8700477408354693 0.6133330624330546 0.8236677400031943 1.0 15.088192185313483 -6.094062783043756 3.437945539582441 0.7989787359018442 1.0027279941408807 0.3661579999684982 0.12046323219297068 0.260259126414835 5.787365739546771 0.03519290853253255 0.04807562830802874 8.052620214485525e-07 6.094062783043756 0.20374925823903645 QAST(ph)VEYLPGMLHSNCPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QASTVEYLPGMLHSNCPK 18 0 Q8ND04-2;Q8ND04 Q8ND04-2 SMG8 Protein SMG8 1 QAS(0.328)T(0.443)VEY(0.229)LPGMLHSNCPK 53.96 0.044538999999999995 8938700.0 38786.0 31909.0 43067.0 39360.0 56195.0 62129.0 58417.0 56438.0 49165.0 41497.0 True False 45351.70374158115 35076.714640765575 44093.88061250702 37154.7868068417 45183.99314918283 58870.84586814635 52883.31885754516 54956.562301003934 49883.94511395814 49020.07760992877 0.9251658902391332 0.7155581213045848 0.8995065443057566 0.7579503872371713 0.9217446269410036 1.2009537466791436 1.078809366202103 1.1211031271372929 1.0176227281993206 1.0 15.581085147870292 -6.564664921894513 5.669939435940048 1.0899481759891096 0.8236577657145248 0.7186939902177436 0.07682566902631528 0.09035508470209158 7.1694587738438065 0.023839415464697807 0.02410522552769666 2.724802807572166e-07 6.564664921894513 -0.2662904102745849 QASTDAGTAGALT(ph)PQHVR ddPTM_PC-9_AZD4547_30min_R2 2 QASTDAGTAGALTPQHVR 18 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 QASTDAGT(0.001)AGALT(0.999)PQHVR;QASTDAGT(0.028)AGALT(0.971)PQHVR 117.27 0.00027307 6435900.0 9401.9 8976.0 16870.4 28428.0 16061.099999999999 16317.9 15758.7 21642.0 19049.2 18383.6 True False 12391.508628331369 11877.316464753152 16646.68747307646 21874.36380822173 13831.293499766283 15297.539133417773 17161.193771352966 18297.726183685347 20056.101822287426 17739.995759532354 0.6985068540206925 0.6695219449740303 0.9383704313532083 1.2330534970093117 0.7796672382142041 0.8623192102623723 0.9673730481097563 1.031439152055789 1.130558433843511 1.0 14.114718044334854 -5.310812831846659 4.8609161471099505 0.9916921830385967 0.6822237567803524 0.5190163172747172 0.11958688532252174 0.15729403605810416 8.438636841829549 0.0331014499948976 0.07454394447634945 4.8886299952981985e-06 5.310812831846659 -0.30946842625824433 QASTDAGTAGALT(ph)PQHVR ddPTM_PC-9_Lapatinib_30min_R1 1 QASTDAGTAGALTPQHVR 18 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 QASTDAGT(0.008)AGALT(0.992)PQHVR 201.48 1.7818999999999998e-54 0.0 9684.9 7693.6 8861.9 3642.7 7574.5 6197.2 5213.9 8573.2 6908.3 7721.4 True False 9546.791550006861 7675.785941893373 8133.308789923253 3910.5963096909777 7128.982802039969 5932.160202378788 5483.8502301913695 8971.542170005332 6130.214506375956 9056.033701881217 1.0541912568218135 0.847588049534188 0.8981093774235529 0.4318221904230134 0.7872080688656293 0.6550505881119343 0.6055465792990815 0.9906701394167368 0.6769204607865497 1.0 13.144663611807857 -4.925313596133439 1.6537591729776648 0.7328619200775593 1.100074155463663 0.22767129160362054 0.16726927632270652 1.0338017678761449 3.466935373622427 0.0460682417802989 0.5611262386335464 1.1876443413998435e-05 4.925313596133439 0.3672122353861037 QATENAKEEVR ddPTM_PC-9_Lapatinib_30min_R1 1 QATENAKEEVR 11 1 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 0 91.70100000000001 0.010433 1601300.0 9250.0 10315.0 14493.0 13470.0 12486.0 15407.0 10866.0 8477.8 14256.0 9901.2 False True 9118.093303757747 10291.116251251717 13301.441484597844 14460.628734602757 11751.598028420492 14748.07852547118 11428.58831225367 8871.709537730512 12650.339157664785 11612.609227480296 0.7851890238569744 0.8862018905190253 1.145430903945434 1.2452523331606522 1.0119687830889281 1.2700055807071378 0.9841533533401645 0.7639721068660722 1.0893623396651275 1.0 13.503404546121041 -10.721842828860563 14.096874365868057 0.9999982081915382 1.0250468793257637 0.0005552115073274022 0.16551044521026673 0.0 0.0 0.17027908690756421 0.04129874477374216 1.8973924631596946e-11 10.721842828860563 0.025048671134225486 QATPGVPAQQS(ph)PSM ddPTM_PC-9_AZD4547_30min_R2 2 QATPGVPAQQSPSM 14 0 R4GMQ1;O60341;O60341-2 R4GMQ1 KDM1A Lysine-specific histone demethylase 1A 1 QATPGVPAQQS(1)PSM;QATPGVPAQQS(0.998)PS(0.002)M 127.07 2.6359e-05 8868100.0 55493.0 48723.0 72664.0 91291.0 77568.0 68435.0 58539.0 87197.0 66659.0 65788.0 True False 73138.61967389504 64471.75691980473 71700.42788218576 70245.27038189009 66799.02212114185 64155.74863159145 63748.85759493045 73722.7072377233 70182.45865295442 63484.7821443088 1.1520653801353822 1.0155466356213116 1.1294112614138263 1.1064899021345598 1.052205266599157 1.010568934233049 1.0041596653828215 1.1612658143827668 1.1055005039384236 1.0 15.954123186298853 -4.7339579843940465 24.541773931769452 1.069360780214217 1.1520659292618403 0.1792619594210747 0.05517799173779758 4673.4857515183985 4173294.0978679853 0.01422259081523549 1.2527537117709084 1.845193922922836e-05 4.7339579843940465 0.08270514904762316 QATPGVPAQQS(ph)PSM ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QATPGVPAQQSPSM 14 0 R4GMQ1;O60341;O60341-2 R4GMQ1 KDM1A Lysine-specific histone demethylase 1A 1 QATPGVPAQQS(0.999)PS(0.001)M 118.16 0.00010532 4546400.0 57679.0 54378.0 56471.0 62802.0 69224.0 61121.0 64154.0 54011.0 56023.0 49454.0 True False 67442.91548782201 59776.28846831778 57817.48280746008 59283.40754683111 55660.054128641896 57915.70716262889 58076.868685262045 52593.268479384875 56842.230389896795 58419.618722351435 1.154456618560885 1.0232228449215688 0.9896929160432714 1.0147859373849215 0.9527630502550041 0.9913742751023853 0.9941329634703991 0.9002672326456422 0.9729989964509794 1.0 15.83416532194852 -1.5228787469574891 0.8226079669487493 0.968484163582163 54.61940467995934 0.7659849237356604 0.029715415811381724 265.44284595554984 0.8350628582432275 0.010528520271584763 26593.293737696946 0.029999999884146474 1.5228787469574891 53.65092051637718 QATPGVPAQQS(ph)PSM ddPTM_PC-9_Lapatinib_30min_R1 3 QATPGVPAQQSPSM 14 0 R4GMQ1;O60341;O60341-2 R4GMQ1 KDM1A Lysine-specific histone demethylase 1A 1 QATPGVPAQQS(0.959)PS(0.041)M;QATPGVPAQQS(1)PSM;QATPGVPAQQS(0.998)PS(0.002)M 114.64 0.00015019 8178900.0 69392.0 61753.0 67173.0 57182.0 62102.0 64964.0 55787.0 55343.0 67250.0 55682.0 True False 68402.45735506571 61610.01472259298 61650.29523527843 61387.355033560125 58449.282457229616 62185.641158480496 58675.3778921126 57914.43781955455 59675.596826105284 65306.55950839875 1.0474056185162963 0.9433970367811157 0.9440138280037534 0.9399875831104746 0.8949986478726191 0.9522112575917142 0.8984607110495026 0.8868088941679199 0.9137764609760326 1.0 15.994940285485974 QATSDVQEST(ph)QESAAVEK ddPTM_PC-9_AZD4547_30min_R2 1 QATSDVQESTQESAAVEK 18 0 G3V5X4;A0A0A0MRE3;Q8WXH0;Q8WXH0-2 G3V5X4 SYNE2 Nesprin-2 1 QAT(0.002)S(0.002)DVQES(0.132)T(0.863)QES(0.002)AAVEK 71.555 0.021779 14252000.0 23053.0 24162.0 28970.0 33570.0 38986.0 37453.0 29823.0 39495.0 34815.0 32299.0 True False 30383.374467812147 31971.893986337505 28585.838871338256 25830.955151329814 33573.46684734472 35111.057989318244 32477.18922519367 33391.95525481254 36655.249823768834 31168.221841050472 0.9748189878382914 1.0257849854055052 0.9171469266716057 0.828759346075651 1.0771697858979683 1.1265017994409554 1.0419968579156866 1.0713461751235767 1.1760455893409874 1.0 14.927788230557843 -6.389009251306876 8.915155188432824 1.0868416401963905 0.9417735914097417 0.5536544944399211 0.0639246384118377 0.2579637961483672 17.414012771322934 0.020430069516284902 0.02315935526554027 4.083106884378987e-07 6.389009251306876 -0.1450680487866488 QATVSWDSGGS(ph)DEAPPKPSRPGYPSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QATVSWDSGGSDEAPPKPSRPGYPSPR 27 2 H0YBP1;E7ESA6;Q05397-7;Q05397;Q05397-5;E9PEI4;H0YB16;H0YBZ1;Q05397-2;B4DWJ1;Q05397-6;E5RHK7;E5RJQ2;E5RG80 H0YBP1 PTK2 Focal adhesion kinase 1 1 QAT(0.003)VS(0.015)WDS(0.161)GGS(0.388)DEAPPKPS(0.217)RPGY(0.193)PS(0.024)PR 45.678999999999995 0.011354000000000001 8143400.0 14576.0 21162.0 23300.0 26523.0 26036.0 19596.0 21059.0 17165.0 19459.0 16665.0 True False 17043.428910877312 23262.82350521425 23855.560365742072 25037.0022987262 20934.43270098983 18568.351263213568 19064.139066043153 16714.436937820847 19743.551062188784 19686.232579932577 0.8657537109589347 1.1816798064718346 1.2117890139152148 1.2718026263820534 1.063404722868591 0.9432150711325774 0.9683995649567017 0.8490419317131775 1.0029116024116587 1.0 14.264899423836408 -6.614433725674577 3.932712767088213 0.9445799315874461 1.1446229646215766 0.3794146357706669 0.10800951571878406 0.2250063958908169 6.6265259851255545 0.03759530643263793 0.03770890744260635 2.429776203103548e-07 6.614433725674577 0.2000430330341305 QATVSWDSGGSDEAPPKPS(ph)RPGYPSPR ddPTM_PC-9_AZD4547_30min_R2 1 QATVSWDSGGSDEAPPKPSRPGYPSPR 27 2 H0YBP1;E7ESA6;Q05397-7;Q05397;Q05397-5;E9PEI4;H0YB16;H0YBZ1;Q05397-2;B4DWJ1;Q05397-6;E5RHK7;E5RJQ2;E5RG80 H0YBP1 PTK2 Focal adhesion kinase 1 1 QATVSWDS(0.003)GGS(0.004)DEAPPKPS(0.353)RPGY(0.33)PS(0.309)PR 53.25899999999999 0.0025029 22995000.0 12234.0 15889.0 29177.0 31184.0 22828.0 21279.0 19203.0 26608.0 25080.0 30827.0 True False 16124.15751699188 21024.80852367009 28790.09391608686 23995.01058799727 19658.72623996269 19948.420766152332 20912.029798859738 22496.34499101283 26405.677598165214 29747.75611300853 0.5420293704082397 0.7067695608300371 0.9678072459218902 0.8066158165625267 0.6608473649333853 0.6705857305798267 0.7029783933758628 0.7562367025449459 0.8876527526262109 1.0 14.860493228920442 -8.428629201422067 2.2387052116816637 0.9979604760163853 0.7297840016577961 0.43293928151878625 0.10370512646138759 0.3048214584878153 3.2136327506239764 0.10707174234980218 0.029758280631654407 3.727097883041074e-09 8.428629201422067 -0.26817647435858916 QATVSWDSGGSDEAPPKPS(ph)RPGYPSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QATVSWDSGGSDEAPPKPSRPGYPSPR 27 2 H0YBP1;E7ESA6;Q05397-7;Q05397;Q05397-5;E9PEI4;H0YB16;H0YBZ1;Q05397-2;B4DWJ1;Q05397-6;E5RHK7;E5RJQ2;E5RG80 H0YBP1 PTK2 Focal adhesion kinase 1 1 QATVSWDSGGSDEAPPKPS(0.545)RPGY(0.325)PS(0.13)PR;QATVSWDSGGS(0.005)DEAPPKPS(0.351)RPGY(0.294)PS(0.351)PR;QATVSWDSGGSDEAPPKPS(0.745)RPGY(0.062)PS(0.193)PR;QATVSWDS(0.002)GGS(0.001)DEAPPKPS(0.34)RPGY(0.317)PS(0.34)PR 74.63 1.8778e-05 61120400.0 137915.0 167379.0 163380.0 190112.0 207823.0 169213.0 184679.0 165407.0 171100.0 143440.0 True False 161261.28555458577 183995.28095072517 167275.59882210058 179460.64099141973 167101.57501988832 160339.172397538 167184.86815982647 161065.24151320328 173602.01381060207 169444.53652958496 0.9517054303278147 1.0858731990960337 0.987199718846611 1.0591114040439182 0.9861726936867772 0.9462634539977796 0.9866642594914002 0.9505484497287485 1.024535918160402 1.0 17.370453594594537 -6.49519534211791 22.60653198610996 0.9774269547844583 1.0231266726382573 0.17782892461468025 0.0401640507835322 313.70513412457376 256174.4019371662 0.01155205815935789 0.013053262747090023 3.197456596286161e-07 6.49519534211791 0.045699717853799005 QATVSWDSGGSDEAPPKPS(ph)RPGYPSPR ddPTM_PC-9_Lapatinib_30min_R1 2 QATVSWDSGGSDEAPPKPSRPGYPSPR 27 2 H0YBP1;E7ESA6;Q05397-7;Q05397;Q05397-5;E9PEI4;H0YB16;H0YBZ1;Q05397-2;B4DWJ1;Q05397-6;E5RHK7;E5RJQ2;E5RG80 H0YBP1 PTK2 Focal adhesion kinase 1 1 QATVS(0.001)WDS(0.064)GGS(0.011)DEAPPKPS(0.408)RPGY(0.36)PS(0.156)PR;QATVSWDS(0.001)GGS(0.006)DEAPPKPS(0.515)RPGY(0.317)PS(0.161)PR 65.836 0.00012032 60491000.0 147545.0 143301.0 143473.0 124398.0 139034.0 128954.0 125890.0 130550.0 150956.0 105370.0 True False 145440.98124356093 142969.19533888713 131677.20376179577 133546.64389956315 130856.29347136118 123438.93802645628 132407.9682154992 136615.82959620643 133953.74564284823 123583.0641033002 1.1768682246136106 1.1568672162019102 1.0654955411344216 1.080622534070968 1.0588529619396834 0.9988337716183874 1.071408685131989 1.1054575364955546 1.0839166888666834 1.0 16.915121523437314 -5.223537635048436 3.021934889642852 1.0599755207593575 1.1752949172189597 0.643609267454833 0.03252054554915278 0.1719478836011784 3.1092467735193146 0.009093270932150701 0.028712000220704997 5.976712495082294e-06 5.223537635048436 0.11531939645960221 QATVSWDSGGSDEAPPKPSRPGY(ph)PSPR ddPTM_PC-9_AZD4547_30min_R2 1 QATVSWDSGGSDEAPPKPSRPGYPSPR 27 2 H0YBP1;E7ESA6;Q05397-7;Q05397;Q05397-5;E9PEI4;H0YB16;H0YBZ1;Q05397-2;B4DWJ1;Q05397-6;E5RHK7;E5RJQ2;E5RG80 H0YBP1 PTK2 Focal adhesion kinase 1 1 QATVSWDS(0.001)GGS(0.001)DEAPPKPS(0.24)RPGY(0.597)PS(0.161)PR 72.158 0.00019025 8034500.0 11428.0 12719.0 15535.0 23207.0 20760.0 20704.0 14914.0 22066.0 14242.0 18121.0 True False 15061.866282833345 16830.168016398762 15328.99574961133 17856.984694575836 17877.832343684306 19409.37560705004 16241.31710775368 18656.206726236065 14994.803044380737 17486.589305603124 0.8613381385932797 0.9624614452977386 0.8766143861284345 1.0211816828599063 1.0223738907138293 1.1099577663684712 0.9287870163765768 1.0668865380316428 0.8575030145859285 1.0 14.093961303930069 -5.766610184747739 24.9997002536341 1.0061697977083195 0.9063703296092641 0.2998065962070705 0.07009558103776417 150.17203637733738 726052.3436806954 0.018793336910668673 0.02884954379064812 1.7115508844530512e-06 5.766610184747739 -0.09979946809905538 QATVSWDSGGSDEAPPKPSRPGYPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 QATVSWDSGGSDEAPPKPSRPGYPSPR 27 2 H0YBP1;E7ESA6;Q05397-7;Q05397;Q05397-5;E9PEI4;H0YB16;H0YBZ1;Q05397-2;B4DWJ1;Q05397-6;E5RHK7;E5RJQ2;E5RG80 H0YBP1 PTK2 Focal adhesion kinase 1 1 QATVS(0.001)WDS(0.017)GGS(0.014)DEAPPKPS(0.31)RPGY(0.282)PS(0.376)PR 51.544 0.0045056 31009000.0 50830.0 71415.0 84382.0 100790.0 96896.0 96128.0 84019.0 108850.0 72971.0 91512.0 True False 66992.88267032032 94498.502153559 83263.0395457807 77554.42268997712 83443.6629467069 90117.10096379944 91496.52823363007 92029.73362416372 76828.09808675101 88308.19273408483 0.7586259054360953 1.0700989254543407 0.9428687981023891 0.8782245484686834 0.9449141734558413 1.0204840363471328 1.0361046399074887 1.0421426458277236 0.8699996649019544 1.0 16.430259668709034 -6.619091390089723 5.4070520928135615 0.9986154352372653 0.9242682790200409 0.16475202256361432 0.08457865087041018 0.4146784221521271 18.949775158344185 0.027669386254698225 0.027637077451755854 2.403856894859606e-07 6.619091390089723 -0.07434715621722432 QAVDVS(ph)PLRR ddPTM_PC-9_AZD4547_30min_R2 1 QAVDVSPLRR 10 1 M0R0F0;M0R0R2;P46782;M0QZN2 M0R0F0 RPS5 40S ribosomal protein S5;40S ribosomal protein S5, N-terminally processed 1 QAVDVS(1)PLRR 60.345 0.031454 4355800.0 47514.0 39961.0 62024.0 73357.0 65580.0 54166.0 49493.0 68642.0 51565.0 57095.0 True False 62622.46364740498 52877.61177005354 61201.521234238324 56445.67700435213 56475.34899319919 50778.99145727743 53897.781119354506 58034.95613624112 54290.620627966106 55096.12142836546 1.1366038484002012 0.9597338324223716 1.1108136044351316 1.0244945658786766 1.0250331153823045 0.9216436682080961 0.9782500060268488 1.053340137775336 0.985380081582573 1.0 15.749663141303898 -6.253071276349854 2.6524507418205228 0.99034310228385 1.0577609738388125 0.2737923713387346 0.053657478199450125 0.4131690664569048 5.7787211670415175 0.017105565531116244 0.021699862128393133 5.583785462071667e-07 6.253071276349854 0.06741787155496248 QAVDVSPLRR ddPTM_PC-9_AZD4547_30min_R2 1 QAVDVSPLRR 10 1 M0R0F0;M0R0R2;P46782;M0QZN2 M0R0F0 RPS5 40S ribosomal protein S5;40S ribosomal protein S5, N-terminally processed 0 155.26 0.00017019 4580200.0 27805.0 26595.0 39874.0 55751.0 57896.0 50505.0 33561.0 53673.0 36584.0 35441.0 False True 36646.41162007187 35191.31365642937 39345.244706791236 42898.46829436364 49858.13975770457 47346.91436601924 36547.86398372816 45379.07113284093 38517.75555228376 34200.22137740085 1.0715255675007835 1.028979118821828 1.150438304846476 1.254333058870505 1.4578309072189315 1.384403739482973 1.068644076318132 1.3268648361097144 1.126242872150994 1.0 15.061718043229181 -5.537191175916722 3.1673900149619594 1.2533583358933427 1.0525962294876439 0.21261632423306398 0.13419885656238245 0.3318107945476154 6.83713440130879 0.03765180742831608 0.07837440415843264 2.902744588452576e-06 5.537191175916722 -0.2007621064056988 QAVDVSPLRR ddPTM_PC-9_Lapatinib_30min_R1 1 QAVDVSPLRR 10 1 M0R0F0;M0R0R2;P46782;M0QZN2 M0R0F0 RPS5 40S ribosomal protein S5;40S ribosomal protein S5, N-terminally processed 0 101.39 0.0022900999999999998 6606800.0 89265.0 77433.0 75750.0 72649.0 74505.0 91183.0 68704.0 65384.0 81551.0 54710.0 False True 87992.0647308039 77253.7086459692 69522.12740345589 77991.84980995946 70122.76238246587 87283.31564795476 72261.15694874618 68421.97933602722 72365.86760989905 64166.55060350733 1.3713073852842306 1.2039560786636165 1.0834636855118067 1.2154595981305008 1.0928242475703995 1.3602619250532673 1.1261499374534931 1.0663184898127793 1.1277817948646838 1.0 15.969533810007935 -1.6614785598276594 0.023234039290601274 2.0264286105999543e-06 2.7066374991199473 0.3838202042412504 0.09170001338636724 2618.468149225959 4.80447816668826 199.2561692851647 389.6405299463652 0.021803260324748424 1.6614785598276594 2.7066354726913366 QAVEMKNDKS(ph)EEEQSSSSVK ddPTM_PC-9_Lapatinib_30min_R1 1 QAVEMKNDKSEEEQSSSSVK 20 2 B4DY08;B2R5W2;G3V4W0;G3V5V7;P07910-2;P07910;P07910-4;G3V2D6;P07910-3 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 QAVEMKNDKS(0.993)EEEQS(0.003)S(0.001)S(0.002)S(0.001)VK 63.446999999999996 0.0073887 10040000.0 92105.0 16705.0 18281.0 18890.0 11892.0 15107.0 7130.4 5894.7 19622.0 8210.1 True False 90791.5658100117 16666.320598852148 16778.006746700696 20279.23361519273 11192.535940571555 14460.90882613702 7499.577222684845 6168.589281660336 17411.963731179734 9629.204845729404 9.428770834621735 1.730809642734284 1.7424083312696186 2.1060133147117193 1.1623530831349482 1.501776009319243 0.7788366062241309 0.640612530368604 1.8082452300204226 1.0 13.233200953708334 -4.760441451479489 5.421054486750131 1.3595103162740583 9.84563038935057 0.9676901687293031 0.44139935826885957 0.026383199909367605 2.383102271182306 0.11947721107690233 0.8439236430303406 1.7360352871356565e-05 4.760441451479489 8.486120073076512 QCEGITS(ph)PEGSK ddPTM_PC-9_AZD4547_30min_R2 2 QCEGITSPEGSK 12 0 Q9Y570-2;Q9Y570;Q9Y570-4 Q9Y570-2 PPME1 Protein phosphatase methylesterase 1 1 QCEGIT(0.419)S(0.534)PEGS(0.047)K;QCEGIT(0.459)S(0.541)PEGSK 189.33 0.0002201 93993000.0 492060.0 442700.0 511820.0 875930.0 934830.0 846190.0 700670.0 831460.0 720050.0 819820.0 True False 648524.8445161873 585794.1175296595 505032.93238275347 673997.8714835957 805044.990840384 793277.6055317651 763028.2726223543 702976.9620500411 758110.3729887897 791118.3513337857 0.8197570482631418 0.7404633156872674 0.638378482222405 0.8519558045231402 1.0176037371439035 1.0027293693722805 0.9644932029903327 0.8885863421886969 0.9582768137164986 1.0 19.593534012510325 -6.003389760607288 5.15157879256695 0.9657990924784674 0.7336545407179582 0.8046803923997887 0.052910100825747146 0.0779088316205121 6.352329260736941 0.016341425851915746 0.023127094257377263 9.922251693296599e-07 6.003389760607288 -0.2321445517605092 QCEGITS(ph)PEGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QCEGITSPEGSK 12 0 Q9Y570-2;Q9Y570;Q9Y570-4 Q9Y570-2 PPME1 Protein phosphatase methylesterase 1 1 QCEGIT(0.439)S(0.56)PEGSK 169.98 0.0010373 28244000.0 155360.0 165950.0 142850.0 218850.0 238090.0 246230.0 300140.0 205350.0 244140.0 219760.0 True False 181659.3795001305 182424.41927465773 146256.08576164182 206588.54402127347 191437.97364336604 233317.26533685808 271708.5663745752 199959.7800863101 247710.08563249712 259600.74838079733 0.6997644676804323 0.7027114536937585 0.5633885367198748 0.7957933299877761 0.737432287223432 0.8987542092699011 1.0466401505746719 0.7702588738033896 0.9541963464186232 1.0 17.985935016802017 -6.5723563125251125 1.644158231044969 0.9310552539372038 0.6738685112222559 0.6575167537469859 0.08517330976438409 0.237048401420789 1.3108865701733274 0.033869925642066825 0.035741153877413626 2.676971129659581e-07 6.5723563125251125 -0.2571867427149479 QCEGITS(ph)PEGSK ddPTM_PC-9_Lapatinib_30min_R1 2 QCEGITSPEGSK 12 0 Q9Y570-2;Q9Y570;Q9Y570-4 Q9Y570-2 PPME1 Protein phosphatase methylesterase 1 1 QCEGIT(0.421)S(0.578)PEGS(0.001)K;QCEGIT(0.077)S(0.915)PEGS(0.007)K 198.81 7.9433e-06 118041000.0 631590.0 549150.0 581440.0 517680.0 976450.0 958910.0 949900.0 880480.0 989140.0 884550.0 True False 622583.4107805801 547878.4769146764 533636.2476233052 555751.9141298549 919017.1307745625 917899.654628387 999081.1741036044 921390.3151502695 877732.6370940341 1037443.2889112099 0.600113198894927 0.5281045072735218 0.5143763069529834 0.5356937772599724 0.8858480657184308 0.8847709213982354 0.9630224464145252 0.8881355973850511 0.8460536074364209 1.0 19.984601044055786 -6.275132430006945 5.696608030059377 0.9085468644966206 0.540020624481554 0.9391942360242516 0.04572323866868211 0.03724447424467536 4.580192255431801 0.013970562289319654 0.016631488830170564 5.307225855946236e-07 6.275132430006945 -0.3685262400150666 QCGQVAAAAAAQPPASHGPER ddPTM_PC-9_Lapatinib_30min_R1 1 QCGQVAAAAAAQPPASHGPER 21 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 0 70.907 0.014012 0.0 15238.0 14454.0 12364.0 14706.0 12318.0 14802.0 12557.0 14265.0 13531.0 11167.0 False True 15020.703325693048 14420.532651051106 11347.479646420186 15787.528297777877 11593.479458119786 14168.952965147288 13207.140018127126 14927.803976942798 12006.996292253243 13097.201070907813 1.146863611879474 1.1010392657926544 0.8664049352976493 1.2054123787444906 0.8851875599491121 1.0818306055192286 1.008394079515471 1.1397705430438276 0.9167604763222129 1.0 13.676970914017549 -5.015363216576233 24.254957861049327 1.0199773691327796 1.135407635426185 0.16074889223340627 0.1027781053951727 719.8995640890059 1136572.2472861407 0.02387676089920627 0.06835235542909734 9.652432725870417e-06 5.015363216576233 0.11543026629340547 QCHPALDGQR ddPTM_PC-9_Lapatinib_30min_R1 1 QCHPALDGQR 10 0 P22692-2;P22692 P22692-2 IGFBP4 Insulin-like growth factor-binding protein 4 0 74.944 0.024492 0.0 4588.7 3180.8 4426.5 2964.8 3455.2 3617.8 3105.1 2781.6 2174.3 3587.0 False True 4523.264296535483 3173.4350530277684 4062.570256784127 3182.8412822828705 3251.971929184565 3463.075127503707 3265.866884629014 2910.843290730047 1929.4074376059582 4207.0081706229375 1.0751736419531879 0.7543211052423208 0.9656673084574915 0.7565569528740855 0.7729892116427816 0.8231681487300093 0.7762920232563828 0.6919034079981439 0.4586174686036486 1.0 12.038578904695518 -1.5228787452803376 0.43715971171531237 0.7276181096869468 6.772359590123363 0.26471030168826715 0.14262142881041331 113.24696234560132 1.4026598159522268 0.09008777794909344 605.8947622052251 0.029999999999999995 1.5228787452803376 6.044741480436416 QDAQDLYEAGEKK ddPTM_PC-9_Lapatinib_30min_R1 2 QDAQDLYEAGEKK 13 1 P09525-2;P09525;Q6P452 P09525-2 ANXA4 Annexin A4;Annexin 0 ; 109.1 0.0016454999999999998 0.0 31148.0 29778.0 29379.0 25325.0 30988.0 26371.0 37049.0 26130.0 24071.0 29325.0 False True 30703.823808156383 29709.05087055486 26963.572026219572 27187.48498172343 29165.34676475206 25243.173803803485 38967.21593785073 27344.09519225484 21359.870501132777 34393.78717689367 0.8927142466236965 0.863791205014896 0.7839663567010196 0.7904766300347537 0.8479829980557022 0.7339457464795351 1.1329725260389343 0.7950300748102864 0.6210386309386337 1.0 15.069860362541226 -10.517128534828084 5.774020611583944 1.000000259765378 0.8333506112125434 0.14411581100276605 0.124555698390604 4.1714420886943756e-07 7.261515895297011e-08 0.12076161406003827 0.029288947720615938 3.039985171277677e-11 10.517128534828084 -0.1666496485528347 QDDGSSS(ph)ASPSVQGAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QDDGSSSASPSVQGAPR 17 0 Q9NQA3 Q9NQA3 WASH6P WAS protein family homolog 6 1 QDDGS(0.031)S(0.031)S(0.832)AS(0.102)PS(0.004)VQGAPR 199.91 1.6346e-12 11649000.0 25656.0 26594.0 31607.0 30305.0 30418.0 29424.0 27927.0 26392.0 24408.0 19390.0 True False 29999.054070902057 29234.0765663769 32360.63075021502 28607.10910013564 24457.81125744005 27880.95364200836 25281.552386029118 25699.237964635468 24764.92082460063 22905.253508844446 1.3097019013266311 1.276304431867069 1.4128038677991297 1.248932219374456 1.067781731732247 1.217229646955998 1.1037447097569606 1.1219800712841783 1.0811895539614136 1.0 14.483390909832952 -6.463508306126955 0.43534551639607805 1.0293694782501175 1.3831125504658233 0.7173031162758343 0.06516492296901191 0.8567532280163012 0.3156003292615326 0.0653928256340597 0.13195880328452192 3.439471331347895e-07 6.463508306126955 0.3537430722157058 QDDGSSS(ph)ASPSVQGAPR ddPTM_PC-9_Lapatinib_30min_R1 1 QDDGSSSASPSVQGAPR 17 0 Q9NQA3 Q9NQA3 WASH6P WAS protein family homolog 6 1 QDDGS(0.008)S(0.132)S(0.48)AS(0.376)PS(0.004)VQGAPR 163.44 3.1143e-05 10872000.0 30704.0 24433.0 31738.0 23206.0 25128.0 26225.0 27908.0 25457.0 30182.0 21276.0 True False 30266.15532957601 24376.426889659047 29128.624152222903 24912.64665294666 23650.02044354879 25103.417883460854 29352.939685107245 26639.825155347557 26782.585329449957 24953.52825151203 1.2129008380905841 0.9768729553578054 1.1673148525783277 0.9983616906533891 0.9477625851212341 1.0060067510469082 1.1763041838914559 1.0675774939254672 1.0732985355618838 1.0 14.606956196357839 QDDGSSSAS(ph)PSVQGAPR ddPTM_PC-9_AZD4547_30min_R2 2 QDDGSSSASPSVQGAPR 17 0 Q9NQA3 Q9NQA3 WASH6P WAS protein family homolog 6 1 QDDGS(0.036)S(0.069)S(0.216)AS(0.678)PS(0.001)VQGAPR;QDDGS(0.003)S(0.05)S(0.164)AS(0.769)PS(0.014)VQGAPR 178.23 3.5076e-06 25386000.0 33869.0 29126.0 38094.0 60728.0 43783.0 37400.0 34133.0 50852.0 32313.0 41691.0 True False 44638.63748103628 38540.40991002674 37588.84866982256 46728.09783824715 37704.486199591985 35061.372087696625 37170.770875617294 42993.991862709896 34020.999211703034 40231.41077975276 1.1095469091404955 0.9579681438718761 0.9343159471986471 1.1614829540544964 0.9371902567873036 0.871492483314603 0.9239241218536688 1.0686672684207101 0.8456327668435819 1.0 15.296034708844504 QDDGSSSAS(ph)PSVQGAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QDDGSSSASPSVQGAPR 17 0 Q9NQA3 Q9NQA3 WASH6P WAS protein family homolog 6 1 QDDGS(0.097)S(0.097)S(0.279)AS(0.448)PS(0.078)VQGAPR 118.66 0.00010949999999999999 11578000.0 11282.0 11292.0 14190.0 14885.0 15624.0 15835.0 15433.0 14655.0 14551.0 11426.0 True False 13191.819770342878 12412.995133771816 14528.343415874679 14051.041707821109 12562.58935782244 15004.584724075661 13971.074514755885 14270.321778256015 14763.780847212543 13497.443351833766 0.9773569280104172 0.9196552865758375 1.0763774321676152 1.0410150531146427 0.930738439151566 1.1116612482049895 1.035090435319943 1.0572610979928465 1.0938205452965826 1.0 13.720398541422746 -4.7576695717523645 0.604343791610026 1.052242103581832 0.877973120362255 0.23156616932101726 0.05485454097662399 5.288880238750408 1.4345662408433215 0.027726664597360506 0.6502409559754933 1.7471509482117887e-05 4.7576695717523645 -0.17426898321957685 QDDGSSSAS(ph)PSVQGAPR ddPTM_PC-9_Lapatinib_30min_R1 1 QDDGSSSASPSVQGAPR 17 0 Q9NQA3 Q9NQA3 WASH6P WAS protein family homolog 6 1 QDDGSSS(0.019)AS(0.949)PS(0.031)VQGAPR 216.31 2.2797999999999996e-22 11257000.0 14091.0 12974.0 14632.0 9930.5 13772.0 14020.0 11694.0 11435.0 14803.0 9789.4 True False 13890.059756027087 12943.959500120185 13429.013441153358 10660.822097176882 12961.958036793776 13420.397282216254 12299.458100818561 11966.311845519873 13135.730257499421 11481.484746444434 1.2097790540834483 1.1273767971628101 1.1696234187230907 0.9285229508734318 1.1289444112015052 1.1688729792871309 1.0712428202831028 1.0422268643631285 1.1440794067655118 1.0 13.487021598028727 QDDS(ph)PPRPIIGPALPPGFIK ddPTM_PC-9_AZD4547_30min_R2 2 QDDSPPRPIIGPALPPGFIK 20 1 A0A0A0MRI1;Q8IXQ4-4;Q8IXQ4 A0A0A0MRI1 GPALPP1 GPALPP motifs-containing protein 1 1 QDDS(1)PPRPIIGPALPPGFIK;QDDS(1)PPRPIIGPALPPGFIK 122.3 4.0878e-06 88805000.0 162220.0 147974.0 189038.0 241849.0 228279.0 205678.0 165715.0 209559.0 166000.0 190237.0 True False 213802.5856143876 195803.70171071554 186531.23260476493 186094.4495798021 196586.40123236546 192816.9221458092 180463.3139675076 177176.47173675837 174774.4211042834 183576.86053363653 1.1646488832682311 1.0666033896730613 1.0160933794299585 1.0137140870524055 1.0708669963137605 1.0503334765902026 0.9830395478107741 0.9651351004790419 0.9520503869400235 1.0 17.48602469605769 -1.5228787452803376 0.4139857675586414 0.9869715378213135 3.8416247018565537 0.6989256068205445 0.03263304796636658 50.70007088797005 0.6568248214484649 0.02585004380726093 119.32483399328993 0.029999999999999995 1.5228787452803376 2.8546531640352404 QDDS(ph)PPRPIIGPALPPGFIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QDDSPPRPIIGPALPPGFIK 20 1 A0A0A0MRI1;Q8IXQ4-4;Q8IXQ4 A0A0A0MRI1 GPALPP1 GPALPP motifs-containing protein 1 1 QDDS(1)PPRPIIGPALPPGFIK;QDDS(1)PPRPIIGPALPPGFIK 90.30799999999999 0.00031864 70841000.0 142592.0 161870.0 164207.0 171996.0 196832.0 176898.0 167483.0 152856.0 148363.0 131116.0 True False 166730.00927962558 177939.38383843863 168122.31763851558 162359.62173855587 158264.1825703346 167621.15746886883 151617.79776808532 148843.69196431906 150532.52819977992 154886.29288631518 1.0764671693834365 1.1488388063432067 1.0854563984039278 1.048250421086171 1.0218088355081154 1.0822207333214495 0.9788974540140302 0.9609868581047949 0.971890574657043 1.0 17.24084994871314 -6.513621520221313 0.6326926202829524 0.9703143673954878 1.1183845585774577 0.6997811208135616 0.03174909772426558 0.4638823875250559 0.4091379971591498 0.02417061459764284 0.034357082555490775 3.0646330424794976e-07 6.513621520221313 0.14807019118196985 QDDS(ph)PPRPIIGPALPPGFIK ddPTM_PC-9_Lapatinib_30min_R1 2 QDDSPPRPIIGPALPPGFIK 20 1 A0A0A0MRI1;Q8IXQ4-4;Q8IXQ4 A0A0A0MRI1 GPALPP1 GPALPP motifs-containing protein 1 1 QDDS(1)PPRPIIGPALPPGFIK;QDDS(1)PPRPIIGPALPPGFIK 99.39200000000001 0.00017011 67831000.0 153807.0 133705.0 137175.0 126460.0 141539.0 135914.0 112329.0 141694.0 133490.0 111435.0 True False 151613.6839752507 133395.41428731053 125897.00101081262 135760.29025819353 133213.95429638066 130101.27505100869 118144.84598998186 148277.6205193782 118454.95048798215 130696.39127219612 1.1600449140136622 1.0206510905836204 0.9632783260909782 1.0387455149809839 1.0192626820042896 0.9954465749559374 0.903964102145149 1.134519622738216 0.9063368111004747 1.0 16.99585978109745 -4.770854420190947 4.044660923370116 0.9987246089172329 1.1758217330008975 0.380125102312436 0.06266506288025704 0.23715032995727983 7.411413505368969 0.014645525105779284 0.12494316056751863 1.6949058544522196e-05 4.770854420190947 0.17709712408366463 QDDSPSGASYGQDYDLS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 2 QDDSPSGASYGQDYDLSPSR 20 0 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 QDDSPSGASYGQDYDLS(0.83)PS(0.17)R;QDDSPSGASYGQDYDLS(0.999)PS(0.001)R 228.23 4.8994e-36 11144500.0 45773.0 44471.0 58558.0 58078.0 68043.0 59296.0 51023.0 69415.0 62235.0 60841.0 True False 60327.86186245458 58845.38107219667 57781.482658882516 44689.01439615527 58596.40395767392 55588.211746311776 55563.94815535178 58688.50674801401 65524.61504472934 58710.975108559134 1.0275397700499056 1.0022892817465392 0.984168335682418 0.7611696844333338 0.9980485564977696 0.946811250256477 0.9463979784463065 0.9996173056144345 1.116053939209347 1.0 15.841342597614988 -7.996250040054893 4.388091899250133 1.0595539937174907 0.9503567486798679 0.24476768326773457 0.07398633863258196 0.27624442043220887 13.112660487629066 0.04940538968106415 0.020092996176387032 1.0086719875697231e-08 7.996250040054893 -0.10919724503762285 QDDSPSGASYGQDYDLS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QDDSPSGASYGQDYDLSPSR 20 0 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 QDDSPSGAS(0.002)YGQDYDLS(0.93)PS(0.069)R 161.68 4.191600000000001e-06 3828400.0 7917.7 12058.0 10672.0 9558.5 12368.0 7563.8 10070.0 9142.1 7116.7 8879.8 True False 9258.010228296742 13255.038551454176 10926.460953785381 9022.968234075111 9944.579184430884 7167.1410126911005 9116.096699513493 8902.129561855632 7220.768274026359 10489.637447541876 0.8825862928624143 1.263631714417388 1.0416433369054017 0.8601792272801133 0.9480384078251703 0.6832591734970436 0.8690573668634985 0.8486594132899934 0.6883715772005506 1.0 13.356677194578795 -5.752203124608509 3.3726615625564147 0.8315304423608085 1.0911116334626652 0.3885717386098544 0.1263537072724596 0.20946255508723713 4.972076062103558 0.034536980034906524 0.059707697416916616 1.7692812512344077e-06 5.752203124608509 0.2595811911018566 QDDSPSGASYGQDYDLS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 2 QDDSPSGASYGQDYDLSPSR 20 0 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 QDDSPSGAS(0.002)YGQDYDLS(0.997)PSR;QDDSPSGASYGQDYDLS(0.696)PS(0.304)R 253.18 5.4422e-66 13033800.0 48819.0 71461.0 79345.0 68953.0 80468.0 80398.0 63965.0 70845.0 78081.0 66626.0 True False 48122.83210769187 71295.5364450507 72821.56038055713 74024.033640465 75735.03044617495 76959.56495689187 67276.79471685128 74136.71733238787 69286.69555061894 78142.21532643537 0.6158365475903267 0.9123818175261222 0.9319106206081891 0.9472988874353401 0.9691948216440432 0.9848654102701974 0.8609532560064452 0.9487409209309625 0.886674318883552 1.0 16.25381453595609 -4.7582620630084955 4.347691446384242 0.9384658270796709 0.5851294415927106 0.8561634971500656 0.03975716107215658 0.07682352845967085 3.025079188444839 0.009804509206870192 0.08654001675276989 1.744769002546748e-05 4.7582620630084955 -0.3533363854869602 QDEHGYISR ddPTM_PC-9_AZD4547_30min_R2 4 QDEHGYISR 9 0 P04792 P04792 HSPB1 Heat shock protein beta-1 0 ;;; 157.97 9.175100000000001e-05 176593000.0 295879.0 295507.0 461628.0 679150.0 531700.0 487325.0 388156.0 527577.0 410225.0 457047.0 False True 389962.36733448075 391023.8587956559 455506.51109762344 522582.46026290266 457882.6328100658 456852.4907122121 422701.1320421914 446052.0971633927 431908.65600906406 441045.92364428076 0.8841763327326414 0.8865830922201892 1.0327870334541527 1.1848708541389537 1.0381745035225958 1.0358388236248157 0.9584061644862064 1.0113506853838414 0.9792827296538257 1.0 18.750569357803336 -5.261261302969679 8.798070613078542 1.034009058834006 0.8851256892717477 0.5016720475787677 0.05758682408086796 0.08422624376442672 106.78783593095694 0.016353195723766707 0.038257694947320155 5.479471810667237e-06 5.261261302969679 -0.14888336956225834 QDEHGYISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QDEHGYISR 9 0 P04792 P04792 HSPB1 Heat shock protein beta-1 0 ;;; 140.78 0.00063393 128186000.0 549310.0 589151.0 659083.0 805712.0 840510.0 712716.0 765371.0 685437.0 695617.0 555710.0 False True 642297.333632958 647638.0177166852 674798.0383061974 760570.5687935485 675818.0991515182 675339.9182951888 692869.518073817 667445.0050305324 705789.082646929 656455.8240020606 0.9784319220708778 0.986567555709053 1.0279412774378542 1.1586012965149062 1.0294951685117457 1.0287667404304557 1.05547013636007 1.0167401683809836 1.0751509192867081 1.0 19.324338403091097 -5.353615566592002 4.2469318917059535 1.0534494310316695 0.9822837429290273 0.30016771958539246 0.04142983455567046 0.2579809668513643 8.153123671477326 0.011100142056418192 0.024969220269303104 4.429803208937741e-06 5.353615566592002 -0.07116568810264223 QDEHGYISR ddPTM_PC-9_Lapatinib_30min_R1 4 QDEHGYISR 9 0 P04792 P04792 HSPB1 Heat shock protein beta-1 0 ;;; 150.15 0.00019380000000000002 181400000.0 768942.0 651368.0 778198.0 618188.0 679771.0 734004.0 662447.0 692268.0 757971.0 542840.0 False True 757976.7460733062 649859.7974159291 714217.5643711489 663651.6077347153 639788.2062612067 702612.3599668951 696745.2642819347 724433.2985285824 672600.3241915221 636669.170711168 1.19053470930065 1.020718180354213 1.1218032806164595 1.0423806244511693 1.0048989894493472 1.1035752825632623 1.094359985270939 1.1378488732529342 1.0564361447566537 1.0 19.28018438105066 -4.746152116798825 24.946544986469288 1.0703416004463393 1.190535042688496 0.3932132322856158 0.04642762127856158 912.6131613797585 1489165.1365511052 0.011498766386930384 0.2679744235318121 1.794105110149335e-05 4.746152116798825 0.12019344224215667 QDENDDDDDWNPCK ddPTM_PC-9_AZD4547_30min_R2 1 QDENDDDDDWNPCK 14 0 Q14974;Q14974-2 Q14974 KPNB1 Importin subunit beta-1 0 107.99 0.0033525999999999994 10836000.0 32331.0 41801.0 47317.0 51215.0 42026.0 52818.0 53872.0 63181.0 55622.0 50531.0 False True 42611.585473423635 55312.355786892425 46689.54566362142 39408.173013862244 36191.415321564404 49515.282110373286 58666.50363610744 53417.828204945225 58562.06536543646 48761.92507043939 0.8738700412641371 1.1343349489789536 0.9575000493966491 0.8081750865441609 0.7422064504074405 1.0154496984859729 1.203121155519605 1.0954823487337737 1.2009793559388848 1.0 15.573467462742055 -7.001409082008523 24.99350350430013 1.129485859275781 0.9102962881100992 0.4742298179176585 0.10994890852149455 51.256021687677105 909167.8447671356 0.041901085889116924 0.036464064102954136 9.967607265759053e-08 7.001409082008523 -0.21918957116568183 QDENDDDDDWNPCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QDENDDDDDWNPCK 14 0 Q14974;Q14974-2 Q14974 KPNB1 Importin subunit beta-1 0 ; 180.84 0.00018452 10264600.0 49067.0 52706.0 41330.0 55531.0 60847.0 45990.0 59337.0 53745.0 43956.0 40888.0 False True 57373.07398257523 57938.30335818079 42315.463944897834 52419.77810393106 48924.46714384423 43578.20343923205 53716.16979732191 52334.25069753461 44598.77334341796 48300.670730770114 1.1878318274786506 1.1995341365160586 0.8760843960276646 1.08528054188152 1.0129148602625249 0.9022277078125626 1.1121205768909093 1.0835098127156004 0.9233572260727666 1.0 15.559755602839008 -5.232946674486098 24.475212017935796 1.0065192452641225 1.1936830982900835 0.5073127495313161 0.07631534014552818 455.27830353645135 391081.62042059953 0.019096067089302105 0.0505013293088446 5.848618929001556e-06 5.232946674486098 0.18716385302596095 QDENDDDDDWNPCK ddPTM_PC-9_Lapatinib_30min_R1 2 QDENDDDDDWNPCK 14 0 Q14974;Q14974-2 Q14974 KPNB1 Importin subunit beta-1 0 ; 166.62 0.0017988 22234000.0 52974.0 96539.0 122074.0 110612.0 110948.0 105938.0 113701.0 117476.0 110324.0 116429.0 False True 52218.581045758176 96315.46987683862 112037.54693926682 118746.77547081505 104422.25677216062 101407.27869353969 119587.88143673433 122934.36382722273 97898.14935677683 136553.59751810896 0.38240355431744116 0.7053308856551056 0.8204657290292849 0.8695982942160679 0.7646979550158884 0.7426188730039985 0.8757578241091397 0.9002645559075796 0.7169210561720583 1.0 17.05910779698503 -4.717769231087337 2.0072045926472106 0.8301202135472385 0.19985782855107437 0.7512885620752416 0.07899776523754638 0.4356978730648602 1.676717124977164 0.0204308672279026 0.5398663646430831 1.9152733640239673e-05 4.717769231087337 -0.6302623849961642 down QDGGQNES(ph)FKR ddPTM_PC-9_Lapatinib_30min_R1 1 QDGGQNESFKR 11 1 A0A0C4DG89;Q7L014 A0A0C4DG89 DDX46 Probable ATP-dependent RNA helicase DDX46 1 QDGGQNES(1)FKR 76.868 0.021958000000000002 0.0 7792.3 13368.0 9739.5 10130.0 13980.0 11790.0 10284.0 13320.0 10955.0 10057.0 True False 7681.180373067196 13337.04721732747 8938.755905557215 10874.993992689377 13157.723885737509 11285.769183832366 10816.455200001541 13938.895827050697 9721.132538735812 11795.339049889839 0.6512047123510989 1.1307048623966456 0.7578210230116867 0.9219738361646282 1.1155019648087516 0.9567990488529253 0.9170109612154438 1.1817291362371545 0.8241503273131094 1.0 13.525929268119578 -4.743646173415589 24.976949186031963 0.9771221600697321 0.6512036933623301 0.37050763626169825 0.1279395012085128 1236.0979100481204 1735061.707164039 0.030575079686978406 0.9581385497099858 1.804487286484319e-05 4.743646173415589 -0.325918466707402 QDGGTAPVASAS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 QDGGTAPVASASPK 14 0 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 QDGGTAPVAS(0.001)AS(0.999)PK 110.34 0.0026741 0.0 14596.0 16506.0 15861.0 17013.0 17999.0 15040.0 17013.0 16415.0 15250.0 13811.0 True False 14387.858363421428 16467.78137112561 14556.969805230561 18264.19277370429 16940.334207395517 14396.774259952388 17893.849894751682 17177.70082590369 13532.384410380748 16198.212947999265 0.8882373882606942 1.016641861913517 0.8986775178201727 1.1275436884511514 1.045815008222121 0.888787812962455 1.1046804948296383 1.060468885120158 0.8354245282379875 1.0 13.983547037519156 -3.8781194587297 1.3971813956904837 1.0047590023695683 1.0785743075910691e-08 0.10360435317277017 0.09163753365235447 31.507294486468282 7.971628626253762 0.025643249470670235 80.53107104465636 0.00013239773067553364 3.8781194587297 -1.0047589915838253 QDGVVVT(ph)INK ddPTM_PC-9_AZD4547_30min_R2 1 QDGVVVTINK 10 0 B5MCP1;H7C0N0;P19827-3;P19827-2;P19827 B5MCP1 ITIH1 Inter-alpha-trypsin inhibitor heavy chain H1 1 QDGVVVT(1)INK 94.302 0.011307 0.0 18781.0 23861.0 28617.0 36550.0 32109.0 28729.0 30998.0 29184.0 26698.0 26501.0 True False 24752.967330932202 31573.60162271332 28237.519881984368 28123.962191870858 27651.21959168397 26932.571088434153 33756.761948917054 24674.283381603967 28109.20177495276 25573.20805627661 0.9679257790598904 1.2346359343431685 1.1041837152321543 1.0997432207168159 1.0812573663356773 1.0531557491405115 1.3200049784380454 0.9648489672201289 1.0991660378743027 1.0 14.64234553178218 QDIAFAYQR ddPTM_PC-9_AZD4547_30min_R2 2 QDIAFAYQR 9 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8 P07355 ANXA2 Annexin A2;Annexin 0 ; 117.31 0.0085963 54222000.0 48804.0 47486.0 59815.0 65642.0 61562.0 60424.0 57361.0 79106.0 53008.0 63483.0 False True 64322.65681373809 62834.9208606582 59021.814017573284 50509.25105879029 53015.17893747077 56645.677727994196 62466.01787701885 66881.98537503989 55809.89466202319 61260.47949272134 1.0499861794483765 1.0257007679498156 0.9634566119350398 0.8244997668487323 0.865405876292068 0.9246691863507949 1.0196788923998015 1.0917639876290304 0.9110260827888923 1.0 15.902669038668233 -7.264808088056962 24.475136151182145 1.0132642442188002 0.9381917350792374 0.14223570705733835 0.07485491782193025 428.5397470200915 3113498.824955611 0.03358411103970728 0.023683956110295647 5.434904433738637e-08 7.264808088056962 -0.07507250913956287 QDIAFAYQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QDIAFAYQR 9 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8 P07355 ANXA2 Annexin A2;Annexin 0 100.02 0.018222 19823000.0 26796.0 17523.0 24246.0 27363.0 31559.0 30910.0 28856.0 24176.0 19933.0 21491.0 False True 31332.03355487569 19262.56763452742 24824.11659346706 25829.939822042925 25375.24049817708 29289.02518605489 26122.550780651567 23541.405616589367 20224.482415468876 25387.14817733762 1.234169089651625 0.7587527161370003 0.9778221807373716 1.0174415669539665 0.9995309564084409 1.153694971229591 1.0289675153025033 0.9272961835707133 0.7966425481977802 1.0 14.631810720911751 -7.883542063177205 4.639945372462889 0.8878288514320619 1.0157910392875382 0.15253654518189363 0.12481085603993716 0.393927177531265 14.006126635856644 0.07126689422334158 0.032736165308309625 1.307548891388256e-08 7.883542063177205 0.1279621878554763 QDIAFAYQR ddPTM_PC-9_Lapatinib_30min_R1 1 QDIAFAYQR 9 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YMW4;H0YKV8 P07355 ANXA2 Annexin A2;Annexin 0 106.88 0.011701999999999999 52047000.0 28026.0 36970.0 38346.0 37350.0 30077.0 34006.0 29877.0 31904.0 42339.0 30843.0 False True 27626.344100661063 36884.39823643003 35193.33989984054 40096.843595947474 28307.929993657162 32551.642651857797 31423.884870716272 33386.376311278174 37570.335970564614 36174.17145428581 0.7637035760604263 1.0196335328106063 0.9728858598548754 1.1084384792784774 0.7825453591779038 0.8998586931837295 0.8686829195363164 0.9229340982548656 1.0385956183693985 1.0 15.14267235269948 -8.253574675447712 23.027007257351123 1.019297801533296 0.9222697373558841 0.14687837118613234 0.09771677784527813 377.63996508194094 1105713.2708252794 0.06982768561666348 0.02519431464479971 5.5773169384263455e-09 8.253574675447712 -0.09702806417741194 QDITLEPS(ph)PTAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QDITLEPSPTAR 12 0 A0A0C4DGJ6;Q96DN6 A0A0C4DGJ6 MBD6 Methyl-CpG-binding domain protein 6 1 QDITLEPS(0.87)PT(0.13)AR 113.43 0.00083449 1804600.0 11365.0 10172.0 13917.0 14070.0 14549.0 14949.0 13204.0 11056.0 8568.0 8667.7 True False 13288.870031018152 11181.808935593961 14248.834060516414 13281.703515555466 11698.227890870377 14165.04812378953 11953.221531318382 10765.791714800307 8693.290790936511 10239.085396524557 1.2978571343421728 1.0920710691005069 1.3916119954769477 1.297157216802163 1.142507112484978 1.3834290442188868 1.1674110595244818 1.0514407584152516 0.84903001139997 1.0 13.321799232306468 -7.811617494152694 2.41708401593862 0.9296268937532867 1.2609664169855295 0.6664873923792504 0.09662103826006252 0.17169457890367074 1.9818812840254378 0.06382232212511182 0.026450939394150687 1.543058907253841e-08 7.811617494152694 0.3313395232322428 QDITLEPS(ph)PTAR ddPTM_PC-9_Lapatinib_30min_R1 1 QDITLEPSPTAR 12 0 A0A0C4DGJ6;Q96DN6 A0A0C4DGJ6 MBD6 Methyl-CpG-binding domain protein 6 1 QDITLEPS(0.986)PT(0.014)AR 175.27 0.0010579 2368100.0 13960.0 13247.0 15097.0 8255.5 13281.0 11088.0 10049.0 9799.4 11647.0 9094.5 True False 13760.927840049537 13216.327385393259 13855.782936105266 8862.637009540684 12499.83769145062 10613.792087390435 10569.288049865369 10254.715898468505 10335.192211652755 10666.47220734048 1.290110504443963 1.2390532810180683 1.299003331820427 0.8308873671879604 1.171881147625215 0.9950611487166496 0.9908888191347622 0.9613971422914681 0.9689419341982869 1.0 13.38079548256004 -5.742591315383306 24.996746309663642 0.9948500342005443 1.2723556059157497 0.7360136890281372 0.0788611555328102 121.78999114268213 161519.51374749275 0.02062835330668411 0.03565272891959819 1.8088755334908323e-06 5.742591315383306 0.2775055717152054 QDITLEPSPT(ph)AR ddPTM_PC-9_AZD4547_30min_R2 2 QDITLEPSPTAR 12 0 A0A0C4DGJ6;Q96DN6 A0A0C4DGJ6 MBD6 Methyl-CpG-binding domain protein 6 1 QDIT(0.008)LEPS(0.088)PT(0.904)AR;QDITLEPS(0.136)PT(0.864)AR 186.69 0.00088572 5633800.0 22618.0 20327.2 32117.0 40720.0 38078.0 37670.0 26289.0 35568.0 28046.0 27614.0 True False 29810.05351637423 26897.569879938746 31691.107595124984 31332.63311772861 32791.52697412385 35314.48894501425 28628.67007145882 30071.78287132984 29528.454302956205 26647.242265047436 1.118691878876914 1.0093941283830206 1.1892828263393496 1.1758302343663865 1.2305786335397164 1.3252586738153929 1.0743577060133676 1.1285138841843418 1.1081242107250995 1.0 14.70169861510782 -8.60184601339522 1.113414768958245 1.0025350286890942 1.1641046698256796 0.26810368793686845 0.08054836111452869 0.908962649138179 2.4201674272610005 0.08391511993605763 0.026684878870453215 2.5012320594898187e-09 8.60184601339522 0.16156964113658545 QDITLEPSPT(ph)AR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QDITLEPSPTAR 12 0 A0A0C4DGJ6;Q96DN6 A0A0C4DGJ6 MBD6 Methyl-CpG-binding domain protein 6 1 QDITLEPS(0.099)PT(0.901)AR 143.05 0.00020367 2962900.0 9847.4 12145.0 16126.0 9784.0 18004.0 16139.0 10786.0 15095.0 14151.0 8603.0 True False 11514.370324984442 13350.675336491215 16510.504998195564 9235.834200155983 14476.245442795398 15292.642428914261 9764.271996122396 14698.772244474543 14357.931603938203 10162.65579868947 1.1330080003761698 1.3136994503162114 1.6246250316108004 0.9088012408475937 1.4244549583842236 1.5047879935957618 0.9607992427906052 1.4463514789480552 1.4128129386995216 1.0 13.310989849269063 -11.007996230353868 3.9149454166953466 0.9970581107632435 1.3050453059773242 0.1436989733183872 0.22204836060608085 0.005556533883717875 0.00073077946097209 0.20952452223462073 0.05036762981862558 9.817564645613622e-12 11.007996230353868 0.3079871952140807 QDITLEPSPT(ph)AR ddPTM_PC-9_Lapatinib_30min_R1 1 QDITLEPSPTAR 12 0 A0A0C4DGJ6;Q96DN6 A0A0C4DGJ6 MBD6 Methyl-CpG-binding domain protein 6 1 QDITLEPS(0.194)PT(0.806)AR 145.86 0.00028231 2077900.0 13336.0 11123.0 14365.0 11761.0 14301.0 12220.0 11456.0 11643.0 12721.0 10359.0 True False 13145.826194477128 11097.245376895084 13183.96515050356 12625.943173545882 13459.843296847788 11697.379086211318 12049.135625361498 12183.976284861208 11288.227021931378 12149.539347500137 1.0820020264539483 0.9133881589657495 1.085141154196621 1.0392116781072667 1.1078480353756999 0.9627837526710958 0.9917360058462383 1.0028344232959052 0.9291074088544781 1.0 13.568613994312535 -6.8047143460179145 24.99999070399276 0.9783721522172761 1.040028829641836 0.28823484892524776 0.053244381062282346 205.0911821225176 118479.8377869202 0.018606786565593187 0.016409776319479635 1.5677819280143876e-07 6.8047143460179145 0.061656677424559936 QDKHY(ph)GY(ph)NSY(ph)SVS(ph)NSEK ddPTM_PC-9_AZD4547_30min_R2 1 QDKHYGYNSYSVSNSEK 17 1 P07858 P07858 CTSB Cathepsin B;Cathepsin B light chain;Cathepsin B heavy chain 4 QDKHY(0.985)GY(0.817)NS(0.391)Y(0.497)S(0.457)VS(0.656)NS(0.197)EK 43.163999999999994 0.044216000000000005 0.0 5713.0 7132.6 6120.9 7309.4 5272.3 5675.3 6419.6 4616.8 7166.0 6003.9 True False 7529.615162217969 9438.073464404892 6039.73286667499 5624.330759104265 4540.332151522486 5320.422593831676 6990.931963586937 3903.379643509774 7544.780130321048 5793.70528844493 1.2996199819198895 1.629022015190927 1.0424646346304052 0.9707657671717494 0.7836663974913957 0.9183108786086897 1.2066426605319012 0.6737276836111674 1.3022374723423529 1.0 12.50027058478426 -5.367135727444028 5.371921766776279 0.9680331923375206 1.460837579622548 0.5111582312291023 0.18679431364718804 0.15145623557980262 6.270313454345915 0.046283782442169415 0.09917530116201012 4.2940220730172615e-06 5.367135727444028 0.4928043872850273 QDKPLS(ph)PAGSSQEAADTPDTR ddPTM_PC-9_AZD4547_30min_R2 2 QDKPLSPAGSSQEAADTPDTR 21 1 P13994 P13994 CCDC130 Coiled-coil domain-containing protein 130 1 QDKPLS(0.997)PAGS(0.002)S(0.001)QEAADTPDTR;QDKPLS(1)PAGSSQEAADTPDTR 90.882 0.00019724 28000000.0 35442.0 39651.0 37284.0 37750.0 40737.0 45581.0 40684.0 40088.0 39268.0 34902.0 True False 46711.81876060378 52467.41033243393 36789.58979906716 29047.320731686028 35081.37072180479 42730.8128644198 44304.79718464872 33893.32073059688 41343.62631278912 33680.091603342 1.3869267135831862 1.5578167348935508 1.0923245171760938 0.8624477947917377 1.0416055613792852 1.2687261474128448 1.3154595215011962 1.0063310138750847 1.2275390102765245 1.0 15.03960844181087 -5.268561916025621 24.500471924315786 1.1049239397198 1.4723717330091617 0.5434893395379539 0.13582518658860684 298.5213858114712 1026873.6662533637 0.037984631637113915 0.0818718760339618 5.388130229853954e-06 5.268561916025621 0.3674477932893616 QDKPLS(ph)PAGSSQEAADTPDTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QDKPLSPAGSSQEAADTPDTR 21 1 P13994 P13994 CCDC130 Coiled-coil domain-containing protein 130 1 QDKPLS(0.998)PAGS(0.001)S(0.001)QEAADTPDTR;QDKPLS(0.848)PAGS(0.127)S(0.025)QEAADTPDTR 62.052 0.0036228000000000002 22211000.0 34264.0 37083.0 33521.0 37923.0 41823.0 28089.4 38216.0 28810.8 29425.0 26139.1 True False 40064.2184551523 40764.35516699082 34320.26776910041 35798.29725802486 33628.08337891758 26616.342415437386 34595.903820119915 28054.547027565895 29855.284958369113 30877.911912998235 1.2975041371980545 1.3201784914034562 1.11148279280676 1.1593496787894961 1.0890659793857902 0.8619864740346346 1.1204094343425006 0.9085636071057049 0.96688160269676 1.0 14.91428757468725 -5.628382251148238 0.7251622341976072 0.9675687632035584 1.3731227610596126 0.722591299789962 0.07632315011963721 0.5987941279625052 0.49570069938417277 0.036809511120468624 0.16719476223076626 2.352977362020246e-06 5.628382251148238 0.40555399785605417 QDKPLS(ph)PAGSSQEAADTPDTR ddPTM_PC-9_Lapatinib_30min_R1 2 QDKPLSPAGSSQEAADTPDTR 21 1 P13994 P13994 CCDC130 Coiled-coil domain-containing protein 130 1 QDKPLS(0.999)PAGS(0.001)SQEAADTPDTR;QDKPLS(0.93)PAGS(0.044)S(0.026)QEAADTPDTR 122.67 1.5235e-06 29660000.0 28178.0 41866.0 41872.0 43743.0 41301.0 50915.0 44261.0 44174.0 46692.0 38306.0 True False 27776.17655278766 41769.06184923935 38429.445790594174 46960.006142370294 38871.75638089019 48737.48413866194 46552.61800926376 46226.48530511541 41433.05527144247 44927.141060463386 0.6182493676908176 0.9297066508867354 0.8553726073705747 1.045248040136163 0.8652176716202841 1.0848116080449133 1.0361802890286917 1.0289211424092923 0.9222277290175545 1.0 15.455299638403396 -4.253100852144062 1.005313083115844 0.9967852391369814 5.134733512553146e-19 0.6887870941360108 0.07262635493112832 2.694819536292783 1.0508565606049856 0.02244858070256835 3.7404084261792665 5.583405214858116e-05 4.253100852144062 -0.9967852391369814 QDKPMDT(ph)SVLSEEGGEPFQK ddPTM_PC-9_AZD4547_30min_R2 1 QDKPMDTSVLSEEGGEPFQK 20 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 QDKPMDT(0.496)S(0.496)VLS(0.008)EEGGEPFQK 63.45399999999999 0.0052929 6647500.0 44878.0 48961.0 57524.0 51300.0 57094.0 74881.0 79609.0 71419.0 69509.0 71172.0 True False 59148.27047961105 64786.68576546113 56761.19417448609 39473.57757709917 49167.48361417687 70198.67923258865 86694.04677693205 60382.83459535275 73183.10383456408 68680.28994307076 0.8612117177816107 0.9433082740210176 0.8264553661834504 0.5747438982831741 0.7158892843191533 1.0221080791996726 1.26228422810668 0.8791872405518995 1.0655619522751827 1.0 16.067608509433285 -6.81887150257548 6.843807246408435 1.0539536370502007 0.7841156750121447 0.5178595272597668 0.1261772776976814 0.1891210224102806 17.75929102634056 0.04802498993384456 0.042595673879833255 1.5174992930494123e-07 6.81887150257548 -0.269837962038056 QDKPMDT(ph)SVLSEEGGEPFQK ddPTM_PC-9_Lapatinib_30min_R1 1 QDKPMDTSVLSEEGGEPFQK 20 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 QDKPMDT(0.498)S(0.498)VLS(0.004)EEGGEPFQK 54.658 0.015519 5146700.0 15697.0 26629.0 24238.0 25619.0 28527.0 28210.0 32501.0 30074.0 24860.0 24643.0 True False 15473.157901522753 26567.342186580896 22245.24520138569 27503.106722478675 26849.0979462399 27003.524060721855 34183.742751385675 31471.347830534727 22060.005012594454 28902.509715266522 0.535356896475662 0.9192053717240972 0.7696648291285093 0.9515819558033511 0.9289538593964387 0.9342968595719696 1.1827257593941596 1.0888794136071624 0.7632556905929243 1.0 14.818907152433278 -4.201180640506058 0.6476666334281538 1.0003560430574485 5.700179471585926e-13 0.5114893206046702 0.12080828053563525 5.564240840133187 1.0269185845509436 0.0540894522465569 4.876745484695086 6.292444004162965e-05 4.201180640506058 -1.0003560430568785 QDKPMDTS(ph)VLSEEGGEPFQK ddPTM_PC-9_AZD4547_30min_R2 1 QDKPMDTSVLSEEGGEPFQK 20 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 QDKPMDT(0.229)S(0.713)VLS(0.058)EEGGEPFQK 63.272 0.012959 7943800.0 22037.0 29732.0 31799.0 34465.0 33999.0 33980.0 40104.0 39830.0 32705.0 40969.0 True False 29044.307601924975 39342.28755905088 31377.324482902506 26519.626728941967 29278.82571545871 31855.225228340438 43673.17830825759 33675.18870234672 34433.71953141918 39534.687779993095 0.7346537745170488 0.9951333820564637 0.7936656704490607 0.6707938829951371 0.7405857326708304 0.8057538080384457 1.1046799851131952 0.8517884064178286 0.8709748695383573 1.0 15.270831410749812 -7.039453793720124 24.439031600093866 0.94603949948461 0.7905214570066443 0.3890894079492496 0.1021870338898107 495.49729897798596 306926.34883462137 0.04080959943774801 0.03161727508178119 9.131585846201778e-08 7.039453793720124 -0.15551804247796563 QDKPMDTSVLS(ph)EEGGEPFQK ddPTM_PC-9_AZD4547_30min_R2 1 QDKPMDTSVLSEEGGEPFQK 20 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 QDKPMDTSVLS(1)EEGGEPFQK 95.223 0.00082824 25402000.0 118650.0 109010.0 135540.0 110660.0 129260.0 135720.0 143360.0 153510.0 125450.0 127670.0 True False 156378.2319266869 144245.3506932645 133742.65103973716 85149.0466799571 111314.48019001144 127233.40694497833 156118.76227488084 129788.55680886895 132081.03088874908 123200.31215972341 1.2693006144655694 1.1708196851502877 1.0855707156516463 0.6911431082217175 0.9035243356014995 1.0327360760257345 1.2671945349657896 1.0534758762672953 1.072083573274654 1.0 16.910646385913736 -5.241450095650569 3.128222029060075 1.0071176664793084 1.238757649792515 0.278926790520146 0.13808972762218338 0.3723054187530435 7.386453699584477 0.04144840401571912 0.124441889613569 5.735217655786088e-06 5.241450095650569 0.23163998331320657 QDKPMDTSVLS(ph)EEGGEPFQK ddPTM_PC-9_Lapatinib_30min_R1 1 QDKPMDTSVLSEEGGEPFQK 20 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 QDKPMDT(0.027)S(0.112)VLS(0.861)EEGGEPFQK 69.649 0.0021451 2693900.0 15552.0 16811.0 19295.0 24810.0 22340.0 23180.0 24311.0 23772.0 28405.0 23918.0 True False 15330.225628112486 16772.07516236477 17708.639580853895 26634.610163733803 21026.0051221299 22188.64543521917 25569.70462536343 24876.533903952626 25205.729782089522 28052.194431268304 0.546489354537793 0.5978881689080916 0.6312746628162182 0.9494661898552081 0.7495315624467981 0.7909771725554081 0.9115046128748567 0.8867945773334603 0.8985296976978749 1.0 14.775826012104599 -4.178611642449733 0.3263427919676513 0.9538012762873557 2.4398946553641392e-18 0.7686840143609946 0.07263626233984019 5.201787877900604 0.33012541628711045 0.07479546901049607 2.114354135156061 6.628089399662058e-05 4.178611642449733 -0.9538012762873557 QDKPMDTSVLS(ph)EEGGEPFQKK ddPTM_PC-9_AZD4547_30min_R2 1 QDKPMDTSVLSEEGGEPFQKK 21 2 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 QDKPMDT(0.01)S(0.01)VLS(0.98)EEGGEPFQKK 40.968 0.036866 6994800.0 16337.0 14401.0 17421.0 21759.0 21673.0 19007.0 12709.0 16578.0 16775.0 18255.0 True False 21531.826169290223 19055.841623096043 17189.986157320807 16742.79872319884 18664.078053211462 17818.48928531685 13840.076379404687 14016.251024541902 17661.69225315875 17615.898006389558 1.2222951200943772 1.0817411417904552 0.9758223027339131 0.9504368563626997 1.0595019366280227 1.0115004797855782 0.7856582942512881 0.7956591835090093 1.002599597633489 1.0 14.104590400584012 -1.52287874528082 0.4775116643832069 0.9098289177954832 9.409922958919383 0.5247508549648878 0.08420562763093543 80.89159011069084 0.9123528935641049 0.05294573505464016 681.5309016112848 0.029999999999966682 1.52287874528082 8.5000940411239 QDLPNAMNAAEITDK ddPTM_PC-9_Lapatinib_30min_R1 2 QDLPNAMNAAEITDK 15 0 P61204-2;P84077;P61204;H0YGG7 P61204-2 ARF3;ARF1 ADP-ribosylation factor 3;ADP-ribosylation factor 1 0 ; 127.03 0.00044003 0.0 25039.0 22110.0 21248.2 24340.0 19691.2 19155.9 22464.0 17991.2 23890.0 24292.0 False True 24681.93926840975 22058.80565343435 19501.255016423936 26130.044795859765 18533.002330388717 18336.64681158391 23627.076002803835 18827.13683210468 21199.256627147282 28490.83983294464 0.86631139738708 0.7742420294654573 0.6844745585166699 0.9171384539407283 0.6504898570577959 0.6435979746157151 0.8292867511572363 0.660813684064673 0.7440727178085524 1.0 14.798210528588067 -10.618755831724135 4.1361116125324555 1.000040687756486 0.7491566347928619 0.40243438150931166 0.0904903864960375 15949738.520530673 5855913.148639984 6383.6762098413865 0.02154642653063569 2.405714956677843e-11 10.618755831724135 -0.25088405296362415 QDPFQESGLHLS(ph)PTAAEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QDPFQESGLHLSPTAAEAK 19 0 H3BN50;Q15599-3;H3BQS0;Q15599 H3BN50 SLC9A3R2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 1 QDPFQES(0.019)GLHLS(0.796)PT(0.185)AAEAK;QDPFQESGLHLS(0.934)PT(0.066)AAEAK;QDPFQES(0.009)GLHLS(0.819)PT(0.172)AAEAK 88.98299999999999 0.0060182 16712600.0 78111.0 99050.0 104993.0 112739.0 152112.0 96878.0 115217.0 89328.0 86619.0 76388.0 True False 91333.649537427 108883.02940135458 107496.43130817004 106422.59933476933 122306.74554512877 91797.54713602805 104302.81166115636 86983.23465083947 87885.63900795142 90236.53971292467 1.0121581548671152 1.2066401232555148 1.1912738636715834 1.1793736736064837 1.3554015472471697 1.017299061201477 1.1558822179239323 0.9639469213642816 0.9739473531182343 1.0 16.46142412553617 -7.549168951767459 1.515713736365408 0.9717949427408266 1.179845736998829 0.42061596588063066 0.0941514433606967 0.3814809429534102 1.6841676769836509 0.06468919295775827 0.03010400774085265 2.8237812373962006e-08 7.549168951767459 0.20805079425800255 QDPFQESGLHLS(ph)PTAAEAK ddPTM_PC-9_Lapatinib_30min_R1 3 QDPFQESGLHLSPTAAEAK 19 0 H3BN50;Q15599-3;H3BQS0;Q15599 H3BN50 SLC9A3R2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 1 QDPFQES(0.002)GLHLS(0.96)PT(0.038)AAEAK;QDPFQESGLHLS(0.958)PT(0.042)AAEAK;QDPFQES(0.001)GLHLS(0.93)PT(0.069)AAEAK 114.72 0.00083899 1961000.0 22299.0 33757.0 39451.0 28383.3 38651.0 36081.0 33127.0 32651.1 39247.0 29771.2 True False 21981.012170864233 33678.8377405239 36207.49106526389 30470.702565913165 36377.62417078972 34537.899738919026 34842.15396834412 34168.18930470082 34826.58957076808 34917.112252369545 0.6295197613133817 0.9645367433911545 1.0369554848513216 0.8726581495537439 1.0418279698465345 0.9891396370149486 0.9978532507647354 0.9785514064778394 0.9974074980500337 1.0 15.091646628337621 -4.7627696020967845 5.183238340205411 0.9874464625620867 0.609147530819109 0.8582003892089114 0.0436344680701429 0.05345234931489196 4.047598874368189 0.01031789549516964 0.07330196079168 1.7267537104962664e-05 4.7627696020967845 -0.3782989317429777 QDPQLHPEDPERR ddPTM_PC-9_AZD4547_30min_R2 1 QDPQLHPEDPERR 13 1 A2IDC7;Q4TT37;A2IDC6;Q13084 A2IDC7 MRPL28 39S ribosomal protein L28, mitochondrial 0 71.268 0.010431999999999999 2622800.0 12791.0 14624.0 16459.0 24922.0 21703.0 17209.0 14989.0 22370.0 17022.0 17515.0 False True 16858.271930672152 19350.92201209337 16240.742905880446 19176.617941061715 18689.913071049166 16132.918509550034 16322.991962459435 18913.23051146111 17921.74816889826 16901.805181151078 0.9974243431389521 1.144902677831925 0.960888066796093 1.1345899290359536 1.1057939001623442 0.9545086064263415 0.9657543550829034 1.1190065385769077 1.0603452102787592 1.0 14.04488971995119 -6.728789545413733 24.999958557214352 1.0239751199624991 1.0706209450500377 0.10992414523074556 0.06884027118742211 494.8627029294074 378914.8574001797 0.023033551161747375 0.02303202615545128 1.8672843381832474e-07 6.728789545413733 0.04664582508753856 QDPS(ph)GAAFQKPVGADVSLGEMDSWK ddPTM_PC-9_AZD4547_30min_R2 1 QDPSGAAFQKPVGADVSLGEMDSWK 25 1 Q6UXI7-4 Q6UXI7-4 1 QDPS(0.999)GAAFQKPVGADVS(0.001)LGEMDSWK 43.622 0.027977 7507600.0 11134.0 6722.2 10474.0 15070.0 10744.0 10361.0 9360.7 12057.0 11523.0 13147.0 True False 14674.380398413248 8895.019690214303 10335.107916409976 11595.844329179043 9252.381054939511 9713.125032102274 10193.784165921283 10193.867692297119 12132.082255329262 12686.72753163536 1.1566718337586677 0.7011279834010675 0.8146393851872805 0.9140138227343407 0.7292961113784437 0.7656131187401816 0.8034998891954032 0.803506472955922 0.9562814543842731 1.0 13.631032361831021 -8.375788599833342 4.043500931674862 0.9967953393732218 0.82652916045425 0.17979117830183566 0.1212617690992157 0.3503383063122074 9.211879709463874 0.11053445965821991 0.029209763898464365 4.2093147402146975e-09 8.375788599833342 -0.1702661789189719 QDPSVLHTEEMR ddPTM_PC-9_Lapatinib_30min_R1 2 QDPSVLHTEEMR 12 0 Q3KNR6;Q8NFI4;P50502;F8WAQ7 Q3KNR6 ST13;ST13P5 Putative protein FAM10A5;Hsc70-interacting protein 0 ; 143.55 5.446e-05 8011300.0 54013.0 47769.0 58330.0 51868.0 59034.0 59920.0 47179.0 47541.0 64379.0 45075.0 False True 53242.764715228914 47658.39381541862 53534.33256031136 55682.54574657576 55561.73618530955 57357.36128034225 49621.6977713801 49749.928416953204 57127.95907907553 52866.15369133783 1.0071238589833857 0.9014916064004764 1.0126390671974121 1.053274011037035 1.0509888143122732 1.0849543096179572 0.9386288637735842 0.9410544354601833 1.0806150077159105 1.0 15.690056745945059 -5.427701800988895 9.361080959910753 1.0203758881849045 0.9545426894845288 0.19605309673208893 0.05365461077200928 0.6453800872747286 59.27826406934823 0.014629442786286407 0.030494996241473237 3.7350653003434832e-06 5.427701800988895 -0.06583319870037574 QDPVTYIS(ph)ETDEEDDFMCKK ddPTM_PC-9_AZD4547_30min_R2 1 QDPVTYISETDEEDDFMCKK 20 1 P35251-2;P35251;D6RAD2 P35251-2 RFC1 Replication factor C subunit 1 1 QDPVT(0.003)Y(0.018)IS(0.662)ET(0.316)DEEDDFMCKK 44.052 0.03439 3458600.0 21113.0 13371.0 19572.0 26210.0 20105.0 16408.0 15783.0 15885.0 11269.0 18902.0 True False 27826.494822318906 17692.91426584384 19312.46249188239 20167.68944046335 17313.767787561308 15382.005166174507 17187.656424277626 13430.338250986122 11864.656333880537 18240.246733321033 1.5255547377813616 0.969993143432795 1.0587829635331987 1.1056697716495956 0.9492068852299433 0.8433002793802603 0.9422929785746511 0.7363024441139694 0.650465780827753 1.0 14.154837624322452 -1.5228787452803398 0.4282993043368766 0.8219977594548629 12.497602586936559 0.6622006939203402 0.13114308594002902 51.51217715029277 0.6496019408237947 0.088973470901734 518.3639919790972 0.029999999999999843 1.5228787452803398 11.675604827481695 QDPVTYISET(ph)DEEDDFMCKK ddPTM_PC-9_AZD4547_30min_R2 1 QDPVTYISETDEEDDFMCKK 20 1 P35251-2;P35251;D6RAD2 P35251-2 RFC1 Replication factor C subunit 1 1 QDPVT(0.086)Y(0.008)IS(0.118)ET(0.789)DEEDDFMCKK 50.028999999999996 0.024127000000000003 8535400.0 26763.0 22716.0 31363.0 43851.0 31945.0 23113.0 28552.0 30446.0 19854.0 25965.0 True False 35273.07729501827 30058.502764408706 30947.10612777985 33741.82944119643 27509.988160837915 21667.74045622813 31093.07268744693 25741.27027947897 20903.441907255663 25055.973253130924 1.4077711904729404 1.199654168718139 1.2351189001972929 1.3466581042498578 1.0979413125530992 0.864773450918359 1.2409445194295785 1.0273506448711751 0.834269804492373 1.0 14.612866957236923 -6.428111701494279 4.644347594396733 1.0076933288915164 1.2840015544321468 0.6012860583238855 0.11615144849035083 0.17331458210286593 6.25744902237027 0.03723351878405642 0.04195894165917349 3.731541693803752e-07 6.428111701494279 0.2763082255406304 QDPVVHLS(ph)PNK ddPTM_PC-9_AZD4547_30min_R2 3 QDPVVHLSPNK 11 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 QDPVVHLS(1)PNK;QDPVVHLS(1)PNK;QDPVVHLS(1)PNK 101.2 0.002172 50331000.0 198204.0 197330.0 212677.0 180565.0 197520.0 220807.0 228036.0 235960.0 234628.0 205363.0 True False 261228.7491006914 261113.0635015303 209856.7640193166 138938.5289514407 170097.7574433782 206999.90338417175 248330.76223573278 199497.80382138392 247029.95707744447 198173.30387763266 1.3181833475511615 1.317599587796959 1.0589557721099416 0.7010960923234745 0.8583283122150982 1.0445398009410456 1.2530989662920045 1.0066835437358863 1.2465349885370012 1.0 17.596403103170154 -5.292188415553954 4.9727043780910325 1.0114818922150577 1.320973031806815 0.37540274600906054 0.15346388531397684 0.19941076971778873 13.412957841468623 0.04454318566758157 0.10252516716776433 5.102835690699902e-06 5.292188415553954 0.3094911395917572 QDPVVHLS(ph)PNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QDPVVHLSPNK 11 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 QDPVVHLS(1)PNK;QDPVVHLS(1)PNK;QDPVVHLS(1)PNK;QDPVVHLS(1)PNK 95.06700000000001 0.0036115 42894000.0 216259.0 243204.0 231540.0 201455.0 240216.0 170244.0 242147.0 171372.0 167230.0 185638.0 True False 252867.37739005263 267347.68584075774 237060.79172033956 190168.12947592232 193147.3992049842 161316.10494256628 219209.0831675365 166873.66658364303 169675.4223819227 219292.69989040078 1.1531044011790268 1.219136277561333 1.0810245477337779 0.8671886003089274 0.8807744138382918 0.7356200412653484 0.999618698101186 0.7609631632381926 0.7737394927725544 1.0 17.74249826087963 -5.661292891358529 2.7425624477870794 0.8480314866665546 1.1846954225758906 0.7092529353843442 0.08696892474667971 0.13243352474831505 2.00249665759096 0.02412142851202348 0.046773992663431074 2.181258359177566e-06 5.661292891358529 0.33666393590933597 QDPVVHLS(ph)PNK ddPTM_PC-9_Lapatinib_30min_R1 2 QDPVVHLSPNK 11 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 QDPVVHLS(1)PNK;QDPVVHLS(1)PNK 103.39 0.0016582 44007000.0 118764.0 189645.0 149524.0 157149.0 171657.0 165009.0 160120.0 165555.0 149270.0 133309.0 True False 117070.40358134967 189205.88865425414 137230.7138993311 168706.26169369623 161560.47275064702 157951.94972476625 168410.2301268229 173247.28968824173 132457.64071721525 156351.28302692325 0.7487652247867418 1.210133265242687 0.877707628889111 1.0790206413889516 1.033317217632469 1.0102376307175387 1.0771272666679883 1.1080643940632648 0.8471797490424586 1.0 17.254431532580384 -4.7345360317334695 24.97346049791432 1.0285574287517896 0.7487637673565732 0.40804897190652023 0.10051072226452024 2765.4143018374903 2566902.859315617 0.02304363351637239 2.0450255356680196 1.8427395976508746e-05 4.7345360317334695 -0.27979366139521633 QDQS(ph)PSLR ddPTM_PC-9_Lapatinib_30min_R1 1 QDQSPSLR 8 0 A0A2R8Y6S3;C9J167;P54278;P54278-3;Q68D20 A0A2R8Y6S3;Q68D20 PMS2;PMS2CL Mismatch repair endonuclease PMS2;Protein PMS2CL 1 QDQS(0.5)PS(0.5)LR 76.332 0.025107 4288200.0 25245.0 32591.0 33407.0 30171.0 38254.0 33036.0 31664.0 31525.0 37093.0 31153.0 True False 24885.00167063399 32515.537541885078 30660.405414749224 32389.87598750556 36003.974930257675 31623.127290677323 33303.40698685809 32989.76658767066 32915.19573339364 36537.75454123677 0.6810763820351521 0.8899161415403295 0.8391431219492613 0.8864769166630126 0.9853910121822985 0.8654918094374748 0.9114793014790121 0.9028952928795385 0.900854366850741 1.0 15.15710035418908 -4.097517946146671 1.1700254683837996 0.9132231562696534 1.2499221146318185e-21 0.6854896792750969 0.04646779495026377 3.805093109715057 1.3968326547707872 0.01339083282553287 6.267596111218311 7.988809292043249e-05 4.097517946146671 -0.9132231562696534 QDQSPS(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 1 QDQSPSLR 8 0 A0A2R8Y6S3;C9J167;P54278;P54278-3;Q68D20 A0A2R8Y6S3;Q68D20 PMS2;PMS2CL Mismatch repair endonuclease PMS2;Protein PMS2CL 1 QDQS(0.329)PS(0.671)LR 78.513 0.022022 3916300.0 24684.0 32873.0 35494.0 31290.0 36256.0 34951.0 27515.0 26808.0 39393.0 30273.0 True False 24332.00163350879 32796.884588211105 32575.820330802173 33591.1709803801 34123.493362038535 33456.22720476038 28939.59206807101 28053.59754741553 34956.14551331991 35505.64771376308 0.6852994720633404 0.9237089505481131 0.9174827788925193 0.946079656148876 0.9610722676328257 0.9422790276768198 0.8150701066313215 0.7901164843851334 0.9845235269365283 1.0 15.11576090502812 -1.5228788585364743 0.017230584381707794 1.6200109944528767 9.55228703624698e-07 0.17849348660369646 0.08642338026702907 10545.114572394477 14.07037256774782 511.65400800983394 851.0038428583274 0.029999992176544255 1.5228788585364743 -1.620010039224173 QDS(ph)EDEEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QDSEDEEER 9 0 A0A3B3ISZ4;Q9BYE7-3;Q9BYE7 A0A3B3ISZ4 PCGF6 Polycomb group RING finger protein 6 1 QDS(1)EDEEER;QDS(1)EDEEER 113.99 0.0010548 0.0 4579.6 8801.599999999999 6707.9 4870.5 5210.5 3344.7 4798.3 2751.67 3558.1000000000004 2989.51 True False 5354.83582877701 9675.364680252038 6867.841775852415 4597.621675374051 4189.539928887215 3169.2980439921616 4343.7702873163435 2679.4415781353623 3610.130481236132 3531.4844980518596 1.5163129929441854 2.7397443442239218 1.9447464032876411 1.301894905077546 1.1863396062472795 0.8974407351187588 1.2300125597925124 0.7587295313383009 1.0222699499962855 1.0 11.786059048264969 -5.817749042111395 2.471236020478082 1.015296509162612 2.176147042970544 0.7081735409856859 0.3026927074140839 0.13858194907387908 1.7240695832915958 0.0863200006215691 0.15114104423179447 1.5214264349154147e-06 5.817749042111395 1.1608505338079318 QDS(ph)LDIYNER ddPTM_PC-9_Lapatinib_30min_R1 1 QDSLDIYNER 10 0 Q9ULQ0-2;Q9ULQ0 Q9ULQ0-2 STRIP2 Striatin-interacting protein 2 1 QDS(1)LDIYNER 81.789 0.015803 3039500.0 7645.6 7410.0 7287.7 4616.1 8575.0 6345.8 5632.3 6879.1 9476.6 5679.0 True False 7536.572341968676 7392.84260026904 6688.533437335527 4955.583392858185 8070.635359098645 6074.404926782307 5923.912934944444 7198.728099389217 8409.245514977978 6660.607583208158 1.13151424217948 1.1099351685132894 1.0041926886967147 0.7440137151078449 1.2116965694609096 0.9119896121933819 0.8893952782744668 1.0807915057986148 1.262534297348226 1.0 12.701438071162855 -7.99561648176246 24.89860817490021 1.1447324127489127 0.9985795018132785 0.1282665416031673 0.13948821485119764 200.8303176279263 1140727.626469561 0.07653998353621416 0.036535028994256695 1.0101445341650726e-08 7.99561648176246 -0.1461529109356342 QDS(ph)LEPVLR ddPTM_PC-9_Lapatinib_30min_R1 1 QDSLEPVLR 9 0 D6RDZ7;D6RD37;D6RAX8;D6RBL1;D6RDZ9;D6RCK9;Q99576-3;E7EWD5 D6RDZ7 TSC22D3 1 QDS(1)LEPVLR 80.17 0.019079 827020.0 3787.8 5854.6 5378.0 3191.0 5814.2 5876.5 6631.7 5852.8 5139.8 4682.8 True False 3733.785277402551 5841.044033405553 4935.841599680344 3425.6767848639474 5472.220187157009 5625.17579379057 6975.056976842687 6124.742454696869 4560.901599506555 5492.215740561218 0.6798322305199571 1.0635132174921975 0.8986976901195034 0.6237331063972184 0.9963592920692212 1.0242088183549334 1.2699896191859983 1.1151678564744465 0.8304301606040885 1.0 12.423172581983339 -6.504604763908483 21.010145698223724 1.0625066543871111 0.8362268597148979 0.3404738912109003 0.15173340313685324 114.76559982016501 131949.5911027731 0.04882694046805908 0.054105404952501296 3.128925596637207e-07 6.504604763908483 -0.22627979467221326 QDS(ph)LVINLNR ddPTM_PC-9_AZD4547_30min_R2 2 QDSLVINLNR 10 0 Q9Y5B9 Q9Y5B9 SUPT16H FACT complex subunit SPT16 1 QDS(1)LVINLNR;QDS(1)LVINLNR 112.08 0.0040749 0.0 21241.4 23462.0 28071.4 24487.1 28950.0 33728.0 25735.7 34925.0 26771.8 23235.7 True False 27995.723351432996 31045.632675583573 27699.15489447307 18841.977416923677 24930.792213374785 31618.982828177323 28026.127443342953 29528.143746659756 28186.902692287054 22422.225215396636 1.2485702503875136 1.3845919562999267 1.2353437104651386 0.8403259371413986 1.1118785925072054 1.4101625741617099 1.2499262305196317 1.316914064639031 1.2570965825877083 1.0 14.452641840026175 -6.712272874428329 24.999987805181167 1.2668231155886822 1.162355162643657 0.054196671113222794 0.1621821361914219 318.16316189954773 161777.01967847045 0.056968170962843956 0.05696805117841637 1.9396667698277085e-07 6.712272874428329 -0.1044679529450252 QDS(ph)LVINLNR ddPTM_PC-9_Lapatinib_30min_R1 2 QDSLVINLNR 10 0 Q9Y5B9 Q9Y5B9 SUPT16H FACT complex subunit SPT16 1 QDS(1)LVINLNR;QDS(1)LVINLNR 112.44 0.0014513 1915300.0 16886.800000000003 23978.0 25056.0 20668.0 23755.0 25787.0 28342.0 26408.0 21665.3 19044.5 True False 16645.991135340162 23922.480414203932 22995.992398956998 22187.993666426864 22357.77760412692 24684.150122433013 29809.41008152893 27635.012087143747 19225.125768276852 22336.31644979887 0.7452433427307597 1.071012781716716 1.029533784168968 0.9933595683198095 1.0009608188698564 1.105112840692015 1.3345714432603928 1.2372233420516654 0.8607115596470682 1.0 14.44710366573873 -6.767343087789156 3.89069894778719 1.1391117884172166 0.9762130547267523 0.17513049832405103 0.1451044127347312 0.35589207241680826 11.865572263759377 0.05220598071862316 0.04854880363653271 1.7086649555488253e-07 6.767343087789156 -0.16289873369046426 QDS(ph)RGSPLLGPVVPGPSPIPSVTEK ddPTM_PC-9_AZD4547_30min_R2 1 QDSRGSPLLGPVVPGPSPIPSVTEK 25 1 P49454 P49454 CENPF Centromere protein F 1 QDS(0.786)RGS(0.214)PLLGPVVPGPSPIPSVTEK 90.211 0.00026496 0.0 14195.0 12072.0 15382.0 19973.0 16577.0 14111.0 9366.4 19299.0 9400.2 17324.0 True False 18708.714725657992 15974.037919173343 15178.02462957974 15368.533429773905 14275.5696898485 13228.636939291111 10199.991454878913 16316.78299690156 9897.07538111135 16717.492033015205 1.1191101325910813 0.9555283703815367 0.9079127778021256 0.9193085541433335 0.853930102772343 0.7913051140186584 0.6101388554416568 0.9760305531881045 0.5920191474633705 1.0 14.029070809329333 -4.528166415939817 0.587483043335723 0.7872828881172548 1.3984071973643875 0.36566377230550273 0.1265759183063469 5.078996037144091 1.0750697953595691 0.06108377583547587 2.2496098140566474 2.963695522725576e-05 4.528166415939817 0.6111243092471327 QDS(ph)WEVVEGLR ddPTM_PC-9_AZD4547_30min_R2 1 QDSWEVVEGLR 11 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;C9J8P4;C9JEF2;C9JZ19;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 QDS(1)WEVVEGLR 101.75 0.0089546 0.0 2622.5 3024.3 3994.9 5807.9 5642.5 4162.2 4645.9 5344.5 5313.6 5856.1 True False 3456.4004486113463 4001.8458315901235 3941.925015778712 4468.978386160513 4859.136271639626 3901.9369760270306 5059.376099699131 4518.630329392215 5594.4660480706025 5651.079721458118 0.6116354075641158 0.708155968211602 0.6975525404128607 0.7908184995499242 0.8598597986838963 0.690476363518764 0.8952937047565996 0.7996047750369193 0.9899817953067369 1.0 12.464310826521269 -3.307387821755011 0.12530165360676554 1.099321712407212 8.226152871829737e-10 0.7353599211651581 0.06405882491041205 28.821863389940415 0.3860539288963484 0.44709262956843165 5.32744835750326 0.0004927335999802179 3.307387821755011 -1.0993217115845968 QDS(ph)WEVVEGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QDSWEVVEGLR 11 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;C9J8P4;C9JEF2;C9JZ19;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 QDS(1)WEVVEGLR 94.53200000000001 0.0065942 1445600.0 4167.9 5188.4 4462.3 5196.4 5977.5 6249.8 7647.1 5991.0 4896.5 6008.1 True False 4873.4431502226635 5703.470063058956 4568.698155366989 4905.262554956104 4806.251784842784 5922.049485855895 6922.711327790428 5833.7425979892 4968.102049232098 7097.320969906566 0.6866595396892161 0.8036088669573078 0.6437215076982964 0.6911428376643759 0.6771923948799595 0.8344063219017496 0.9753978095599027 0.8219640372367152 0.6999968115148527 1.0 12.793058837053378 -6.837862948921027 5.327364770316389 0.8649190415522632 0.7026827111969695 0.48218890679381554 0.08631860537488129 0.1971982076145214 9.824726000830726 0.03104229275847997 0.027553534122957423 1.4525699353354737e-07 6.837862948921027 -0.16223633035529372 QDS(ph)WEVVEGLR ddPTM_PC-9_Lapatinib_30min_R1 2 QDSWEVVEGLR 11 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;C9J8P4;C9JEF2;C9JZ19;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 QDS(1)WEVVEGLR;QDS(1)WEVVEGLR 139.77 0.0001026 0.0 7944.5 8090.3 8023.1 8594.0 10467.0 10308.900000000001 10765.3 9929.8 11226.4 11233.4 True False 7831.209973157129 8071.56740741655 7363.471688061619 9226.031428743578 9851.351638913762 9868.012378219628 11322.67455898255 10391.17475851711 9961.964612767106 13175.07822243538 0.5943957099109768 0.6126390501174983 0.5588939635684759 0.7002638825348977 0.7477262352900675 0.74899080002544 0.8594009362086035 0.7886992838359276 0.7561218570834156 1.0 13.685523906936387 -4.549952655196247 0.1106818566777186 1.1464741920626789 1.5493564177056594e-14 0.8485608021043942 0.04865494278473515 19.291118985248808 0.3245053247559635 0.6821713965484187 3.504778885214137 2.818690195265926e-05 4.549952655196247 -1.1464741920626633 QDSGT(ph)MKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QDSGTMKK 8 1 A0A075B784;Q9P275;E9PEW0 A0A075B784 USP36 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 36 1 QDS(0.018)GT(0.982)MKK 58.917 0.035004 2345700.0 12496.0 16708.0 12159.0 12870.0 11595.0 10179.0 12926.0 10453.0 10462.0 10800.0 True False 14611.32599274992 18366.65982067478 12448.91667326429 12148.935625102975 9323.042985403948 9645.19532089462 11701.555703864087 10178.619825868996 10614.986957840536 12757.954507247043 1.1452718368332546 1.4396241819362001 0.9757768509201685 0.9522635950929187 0.7307631470317657 0.7560142431465602 0.9171968513618012 0.7978253739725378 0.8320289080675736 1.0 13.639109418776991 -5.492220888562914 2.777668146729285 0.839380122224655 1.2919237870215754 0.715254159130093 0.10734294844878892 0.12613872749812619 1.926001937031705 0.02864436982035532 0.06545774014179488 3.2194309248640384e-06 5.492220888562914 0.45254366479692043 QDTS(ph)SSTTHLAQQLK ddPTM_PC-9_Lapatinib_30min_R1 1 QDTSSSTTHLAQQLK 15 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 QDT(0.133)S(0.413)S(0.413)S(0.023)T(0.016)T(0.002)HLAQQLK 100.68 0.0094824 0.0 13166.0 11868.0 16065.0 10374.0 13517.0 12926.0 10948.0 8702.2 13152.0 7756.9 True False 12978.2504256513 11840.52037516774 14744.197712693333 11136.93856664951 12721.95663544448 12373.185111977698 11514.833871024592 9106.535980942985 11670.68326330017 9097.669829580445 1.4265466508196873 1.3014893480382312 1.6206564965408605 1.2241528627955396 1.3983752844140283 1.3600389268631339 1.2656904555477386 1.0009745518939048 1.282821148922524 1.0 13.151281362304365 -7.494341721137517 3.1204408934695933 1.106217462479083 1.3877187648973979 0.5379460393152649 0.12108981611377923 0.19861901643109614 3.924473193151442 0.0574233807812291 0.03342921480012309 3.2037474894195725e-08 7.494341721137517 0.28150130241831484 QDTSSS(ph)TTHLAQQLK ddPTM_PC-9_AZD4547_30min_R2 1 QDTSSSTTHLAQQLK 15 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 QDT(0.035)S(0.034)S(0.136)S(0.716)T(0.062)T(0.018)HLAQQLK 99.796 0.0019924 6042400.0 11700.0 10958.0 23494.0 37432.0 37134.0 41250.0 28427.0 51791.0 30466.0 34544.0 True False 15420.356624881899 14499.959204630684 23182.4542092931 28802.630718635006 31978.585079497723 38670.630979077185 30956.947929603986 43787.8909887833 32076.37056242827 33334.62507437527 0.4625927722443687 0.43498191961897836 0.6954466761683705 0.8640454378704243 0.9593203765798479 1.160073973917402 0.9286724497585835 1.3135858252818204 0.9622538273900002 1.0 15.02473388028427 -5.705392750861529 1.0823827226160978 1.0859066294421393 0.39262598668278925 0.8348164831507401 0.10774649431452288 0.21035761681456294 0.46236161676465737 0.037646496516620914 0.11716256133092555 1.970639797157542e-06 5.705392750861529 -0.6932806427593501 down QDVDLCLVSS(ph)CEYK ddPTM_PC-9_AZD4547_30min_R2 2 QDVDLCLVSSCEYK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QDVDLCLVS(0.008)S(0.992)CEYK;QDVDLCLVS(0.019)S(0.981)CEYK 235.35 7.652e-27 8122700.0 91632.0 132507.0 105229.0 80081.0 95783.0 133598.0 128579.0 142237.0 123749.0 109408.0 True False 120769.0699359982 175337.29643438544 103833.59470459294 61619.56268911658 82485.18378492823 125244.09594043018 140022.2819094718 120257.53993109928 130290.11950140925 105577.65922120344 1.1438884971200785 1.6607424120573038 0.9834807427113307 0.5836420616222694 0.7812749817848065 1.1862746045356258 1.3262491604980646 1.1390434379600987 1.234069029968063 1.0 16.68794505969516 -6.952800373548486 24.999522961447003 1.1964054661754098 1.032724942312929 0.06601131292114659 0.27096756713798614 385.18801708276925 204015.49953443353 0.10817291399429416 0.09539951079352273 1.114806844487767e-07 6.952800373548486 -0.16368052386248078 QDVDLCLVSS(ph)CEYK ddPTM_PC-9_Lapatinib_30min_R1 2 QDVDLCLVSSCEYK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QDVDLCLVS(0.01)S(0.99)CEYK;QDVDLCLVS(0.263)S(0.737)CEYK 211.49 1.8324e-11 6391700.0 36807.0 93283.0 80964.0 92255.0 99977.0 81511.0 104423.0 93079.0 78769.0 83745.0 True False 36282.12543042288 93067.00894479058 74307.45245007804 99039.7404536584 94096.54942234464 78024.96454142155 109829.51199433696 97403.79014159525 69897.20574565779 98220.21166680154 0.36939571616384786 0.9475341924583457 0.7565393231095426 1.0083437896635472 0.9580161539618155 0.7943880716334683 1.1181966535250236 0.9916878460008223 0.7116377022559713 1.0 16.583732311126816 -4.759796073294021 24.999883894490143 0.9214438739632109 0.3693950333982801 0.6508507401267458 0.12113715965778615 25.90935237424151 394041.7030782054 0.029507419664539715 0.18279638853443897 1.738617019671606e-05 4.759796073294021 -0.5520488405649309 QDVDNASLAR ddPTM_PC-9_Lapatinib_30min_R1 3 QDVDNASLAR 10 0 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 0 ;; 136.49 0.00053189 44129000.0 99285.0 128424.0 124011.0 123935.0 130644.0 111387.0 124463.0 111198.0 116636.0 110303.0 False True 97869.17769336082 128126.64211834678 113815.29427630358 133049.59333504032 122959.77677598647 106623.23766577899 130907.08513786399 116364.66502825689 103499.22544847004 129368.72658049113 0.7565134192804178 0.9903988815923642 0.8797744036344792 1.028452523665053 0.9504598215201793 0.8241809321624552 1.0118912707733558 0.8994806403683403 0.8000328068783648 1.0 16.98112937878284 -4.748611646926203 24.822512679066985 0.9296329166981282 0.7565129709903352 0.32625446933502644 0.07544593634369409 690.7004481857875 1336463.9476789148 0.018272091606056858 0.3248974790523766 1.7839733118847266e-05 4.748611646926203 -0.173119945707793 QDVPPS(ph)PSQVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QDVPPSPSQVAR 12 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-5 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 QDVPPS(0.774)PS(0.226)QVAR 95.822 0.013741 0.0 17983.0 19433.0 25741.0 22698.0 33565.0 27402.0 22070.0 21885.0 19956.0 17969.0 True False 21027.16671956 21362.17981177716 26354.763063286115 21426.30464790887 26988.17919836855 25964.990881535927 19979.369827037004 21310.54193907422 20247.818746957153 21226.637457474277 0.9906028103455434 1.0063854840209352 1.2415891643735657 1.0094064446540159 1.2714297896893478 1.223226756171557 0.9412404516289467 1.0039527919468187 0.9538872460379981 1.0 14.373588229471821 -7.27729486074435 24.958394173964486 0.9750995127329019 1.1253060130222037 0.3636159125904529 0.09655625803518857 963.6835525155956 1516945.3475241084 0.042059727505113116 0.028470266595854887 5.2808658989219805e-08 7.27729486074435 0.15020650028930183 QDVPPS(ph)PSQVAR ddPTM_PC-9_Lapatinib_30min_R1 1 QDVPPSPSQVAR 12 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-5 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 QDVPPS(0.757)PS(0.243)QVAR 73.252 0.023099 3409300.0 18056.0 19726.0 25594.0 22859.0 20773.0 23736.0 13848.0 19522.0 24813.0 13679.0 True False 17798.518128935128 19680.325658961836 23489.76011569706 24540.127115388586 19551.172981289365 22720.866611318466 14564.981681215604 20429.06338856485 22018.298647526393 16043.396923878205 1.109398353315356 1.2266931842639015 1.4641388121948198 1.5296091739065725 1.218642976550082 1.4162129578369929 0.9078489892335582 1.273362710247431 1.372421236724215 1.0 13.969692020492719 QEAEQLR ddPTM_PC-9_Lapatinib_30min_R1 1 QEAEQLR 7 0 Q9BRK4;Q9HAV0;P62879;C9JD14;C9JZN1;C9JIS1;C9JXA5 Q9BRK4;Q9HAV0 LZTS2;GNB4;GNB2 Leucine zipper putative tumor suppressor 2;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0 90.37 0.027047 0.0 10428.0 14281.0 14476.0 11644.0 12041.0 11564.0 11423.0 11572.0 14889.0 9403.0 False True 10279.29480773901 14247.933221922021 13285.83915897596 12500.338603245313 11332.772053516826 11069.434677000632 12014.427046831739 12109.677365662967 13212.04403187927 11028.296021290063 0.9320836861737198 1.291943306057116 1.204704619220206 1.1334786969005437 1.0276086198302052 1.0037302821425134 1.08941825859933 1.0980551612221237 1.198013184119604 1.0 13.428922277319897 -6.058450244873042 6.778426593261632 1.0724914076268992 1.1596969481306738 0.10137519474159762 0.10001240665808835 0.49056073427758023 47.35650613733173 0.029374168223646673 0.038447779497664404 8.740771258620459e-07 6.058450244873042 0.0872055405037746 QEAGDS(ph)PPPAPGTPK ddPTM_PC-9_AZD4547_30min_R2 2 QEAGDSPPPAPGTPK 15 0 J3KR72;P49848-4;P49848-2;P49848;P49848-3 J3KR72 TAF6 Transcription initiation factor TFIID subunit 6 1 QEAGDS(0.503)PPPAPGT(0.497)PK;QEAGDS(1)PPPAPGTPK 171.33 2.069e-05 26618000.0 61011.0 67908.0 78725.0 81185.0 79817.0 87872.0 71084.0 91680.0 70232.0 77494.0 True False 80411.22889236482 89857.93298668199 77681.05506199872 62469.052545746505 68735.78729170749 82377.34994893246 77410.33829204515 77512.96259681512 73944.32013853031 74780.9586473377 1.0752901587097743 1.2016151519325442 1.0387812147252309 0.8353604136093873 0.9191616226245659 1.1015818924897562 1.0351610850177442 1.036533417047532 0.9888121451778531 1.0 16.190383345354988 -5.511548460066837 24.884667026088504 0.9890927501390643 1.1338890690085646 0.39728646791165856 0.07327374074529396 529.3726770344546 1162657.7917701926 0.021219344915247275 0.04039173473371745 3.079296723848978e-06 5.511548460066837 0.14479631886950028 QEAGDS(ph)PPPAPGTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QEAGDSPPPAPGTPK 15 0 J3KR72;P49848-4;P49848-2;P49848;P49848-3 J3KR72 TAF6 Transcription initiation factor TFIID subunit 6 1 QEAGDS(1)PPPAPGTPK;QEAGDS(1)PPPAPGTPK;QEAGDS(0.799)PPPAPGT(0.201)PK 148.19 4.914600000000001e-05 23234000.0 100715.0 116652.0 113093.0 126250.0 133715.0 108718.0 118787.0 95160.0 95481.0 87271.0 True False 117764.060288077 128232.4396337892 115789.56602759095 119176.62180802226 107514.50563115899 103016.63669289909 107534.63541659483 92662.15083035408 96877.22899269487 103092.54146314404 1.1423140667278835 1.2438575847859252 1.1231614274344583 1.1560159456407264 1.0428931531346117 0.999263721999985 1.0430884125117708 0.8988249733224507 0.9397113274904455 1.0 16.65358043485019 -6.452927815261377 0.8884512608906908 0.9518249309034463 1.194146283259659 0.8031108998614102 0.044833506370023736 0.23777550325694793 0.41028356933352955 0.023901892499945485 0.031194250750286544 3.524294440022247e-07 6.452927815261377 0.24232135235621266 QEAGDS(ph)PPPAPGTPK ddPTM_PC-9_Lapatinib_30min_R1 1 QEAGDSPPPAPGTPK 15 0 J3KR72;P49848-4;P49848-2;P49848;P49848-3 J3KR72 TAF6 Transcription initiation factor TFIID subunit 6 1 QEAGDS(0.969)PPPAPGT(0.031)PK 176.46 5.3182e-05 14201000.0 25318.0 36750.0 34081.0 30316.0 36470.0 32043.0 30200.0 30723.0 30913.0 23745.0 True False 24956.960677247425 36664.907632913295 31278.991736464453 32545.539771211344 34324.90630277874 30672.59558588128 31763.608230265127 32150.502739825704 27431.252411678674 27849.29161177632 0.8961434648016021 1.3165472265516878 1.1231521495231804 1.1686307940934906 1.2325234975910178 1.1013779457467816 1.1405535434457372 1.1544459797401303 0.984989233983931 1.0 14.765353010483693 -8.260879340884745 24.608699830474595 0.9924945926263318 1.149430302433277 0.25508756962337176 0.10127764490045509 48.634950797583194 2137419.299007683 0.07313194039040742 0.023764924092037863 5.484293127099875e-09 8.260879340884745 0.15693570980694527 QEAGDSPPPAPGT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 QEAGDSPPPAPGTPK 15 0 J3KR72;P49848-4;P49848-2;P49848;P49848-3 J3KR72 TAF6 Transcription initiation factor TFIID subunit 6 1 QEAGDS(0.274)PPPAPGT(0.726)PK 164.97 5.0422e-05 4843000.0 61500.0 63842.0 58840.0 66535.0 71133.0 68512.0 72103.0 76458.0 74065.0 66012.0 True False 81055.720720533 84477.67800164544 58059.74315462699 51196.38370550276 61257.41079495644 64227.93380941898 78520.02731798068 64643.17293005339 77979.92469330574 63700.93997248899 1.2724415174334816 1.3261606192644797 0.9114424870292603 0.8036990306204796 0.9616406103491117 1.008272936587083 1.2326353010158364 1.014791507911364 1.2241565780188413 1.0 15.959027040628248 -5.251327157500682 24.822047707114187 1.017534097578851 1.2993011127767025 0.4533571722380433 0.12284541130477 609.3950263671261 1495848.1006630114 0.03426373371960421 0.08842126759101919 5.606254932624457e-06 5.251327157500682 0.2817670151978515 QEAKPQQAAGMLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 QEAKPQQAAGMLSPK 15 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 QEAKPQQAAGMLS(1)PK;QEAKPQQAAGMLS(1)PK 89.831 0.0020811 66865000.0 166321.0 211410.0 129061.0 102868.0 136442.0 183465.0 214795.0 172595.0 197525.0 158209.0 True False 219207.61830828906 279744.1481521236 127349.5668130408 79153.37189475699 117499.38346035512 171992.90454730616 233911.33888694842 145924.40858853958 207965.76824472015 152670.15106507158 1.435824991192009 1.8323434292855985 0.8341484299623274 0.5184600351971878 0.7696290508697679 1.1265653655769212 1.5321353732547887 0.9558149223704062 1.3621900993343505 1.0 17.22005849911386 -5.262841335843351 24.999682307024766 1.0071226573085796 1.6340842308198429 0.42914175301544233 0.28677326279314586 117.9333295093312 2103032.0944834435 0.08186801034370882 0.1865906746719511 5.459572834509838e-06 5.262841335843351 0.6269615735112632 QEAKPQQAAGMLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 6 QEAKPQQAAGMLSPK 15 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 QEAKPQQAAGMLS(1)PK;QEAKPQQAAGMLS(1)PK;QEAKPQQAAGMLS(1)PK;QEAKPQQAAGMLS(1)PK;QEAKPQQAAGMLS(1)PK;QEAKPQQAAGMLS(1)PK 89.557 0.0021217 165671500.0 238475.0 489926.0 339986.0 452883.0 532359.0 432626.0 534959.0 538010.0 388552.0 458683.0 True False 235074.3027690406 488791.6064479647 312033.66346391285 486189.5265934011 501046.6902780643 414123.59448046255 562656.5594455097 563007.9087020666 344789.18212604953 537965.7453933198 0.43696890514315573 0.9085924348038132 0.5800251524114747 0.903755547182537 0.9313728514661039 0.7697954712296539 1.0458966286675704 1.0465497357837124 0.6409128928347767 1.0 19.037154787507724 -4.220787778732776 0.5966823701567681 0.9193801631611689 1.3605832489636773e-16 0.38010905076254475 0.15756608851842577 7.508727030192876 1.245041534240471 0.07422813090734685 5.5035524912745935 6.0146757734241166e-05 4.220787778732776 -0.9193801631611688 QEASES(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 2 QEASESPVK 9 0 Q01167-2;Q01167;E9PPI7;Q01167-3 Q01167-2 FOXK2 Forkhead box protein K2 1 QEAS(0.008)ES(0.992)PVK;QEAS(0.138)ES(0.862)PVK 112.02 0.0021958000000000004 21997000.0 90748.0 89100.0 102969.0 90686.0 94789.0 104082.0 100472.0 112916.0 106409.0 99455.0 True False 119603.97632434005 117899.83255453501 101603.56378125066 69779.74378473326 81629.1835272393 97573.73608640762 109413.81335994577 95467.42675154876 112033.5625017211 95973.11072174605 1.2462238164927961 1.2284673453626078 1.058666985129084 0.7270759826368973 0.8505422291031707 1.0166778522924222 1.1400465457159998 0.9947309828097224 1.1673432449901406 1.0 16.55034263473425 -5.337941585651697 4.062897502412227 0.98183405514876 1.2398350619990335 0.40196125826002627 0.12043662997299674 0.228794078047895 7.1228550755909685 0.035472797154683114 0.08178982375838262 4.592597809638235e-06 5.337941585651697 0.2580010068502735 QEASES(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QEASESPVK 9 0 Q01167-2;Q01167;E9PPI7;Q01167-3 Q01167-2 FOXK2 Forkhead box protein K2 1 QEAS(0.009)ES(0.991)PVK;QEAS(0.01)ES(0.99)PVK 111.94 0.0022015999999999997 15858400.0 52219.0 64482.0 61323.0 54699.0 69562.0 51379.0 63068.0 45866.0 42387.0 42314.0 True False 61058.64532773752 70883.34681330797 62785.17288877254 51634.392366550666 55931.82545499515 48684.59479243977 57093.74246722111 44662.066099044045 43006.82968667433 49985.19324256029 1.2215346458988707 1.4180868816358556 1.256075425858584 1.032993753089788 1.118967874818008 0.9739803256574565 1.1422130987903871 0.8935059204895935 0.8603913858645609 1.0 15.60921317845441 -5.925122547283945 0.6991868451649391 0.9507499869311092 1.3748143176469043 0.6724774689698155 0.09441972087247118 0.577574796181656 0.5291603173413011 0.05375388095302777 0.1558569704540586 1.1881669084798972e-06 5.925122547283945 0.4240643307157951 QEASES(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 2 QEASESPVK 9 0 Q01167-2;Q01167;E9PPI7;Q01167-3 Q01167-2 FOXK2 Forkhead box protein K2 1 QEAS(0.325)ES(0.675)PVK;QEAS(0.001)ES(0.999)PVK 127.56 0.0013584 23370000.0 42304.0 60686.0 54350.0 61673.0 75882.0 59078.0 63940.0 59939.0 54676.0 56380.0 True False 41700.73720239656 60545.48529553672 49881.552797067074 66208.63815509682 71418.7699497521 56551.37165754436 67250.5003391772 62723.98475807744 48517.81311619525 66125.20787837234 0.6306329846115414 0.9156188273449558 0.7543500337846484 1.0012617015416865 1.0800536170883044 0.8552165425560907 1.017017601863342 0.9485638952311355 0.7337264361487782 1.0 16.01291273219578 -4.184297312883891 1.0670125907720327 0.9393955995471505 4.3313863874332256e-10 0.3952228274636477 0.10775482192378553 5.754094892343352 2.1956111326647 0.03349556797257809 8.339411666145097 6.541881712240167e-05 4.184297312883891 -0.9393955991140118 QEASTGQSPEDHASLAPPLSPDHS(ph)SLEAK ddPTM_PC-9_AZD4547_30min_R2 1 QEASTGQSPEDHASLAPPLSPDHSSLEAK 29 0 P48681 P48681 NES Nestin 1 QEASTGQS(0.001)PEDHAS(0.038)LAPPLS(0.24)PDHS(0.36)S(0.36)LEAK 45.878 0.022068 6645000.0 1928.7 2534.2 8774.3 33127.0 17872.0 16471.0 6910.7 22296.0 9998.1 16379.0 True False 2541.986480547839 3353.330591017985 8657.947048974227 25490.08195704803 15390.781293175618 15441.065766215283 7525.73891220018 18850.665511110274 10526.57915447431 15805.576195379594 0.16082846010327242 0.21216123661459785 0.5477780083401947 1.6127271566663597 0.9737564200712131 0.9769378588506715 0.4761445466569046 1.1926591778805788 0.6660041383085749 1.0 13.948146009481162 -5.528484460307806 24.987720979545553 0.9797958628837833 0.23486342349098968 0.5659550686188624 0.28363570360195467 101.2615340299218 451376.3883732538 0.07801780873831499 0.1356557774563549 2.961525931230842e-06 5.528484460307806 -0.7449324393927936 QECLDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QECLDSR 7 0 P25786;P25786-2;F5GX11;B4DEV8 P25786 PSMA1 Proteasome subunit alpha type-1;Proteasome subunit alpha type 0 136.27 1.4948e-08 0.0 103060.0 96494.0 109870.0 124740.0 124780.0 121970.0 116090.0 118150.0 107100.0 98001.0 False True 120506.0224722155 106073.28661337032 112489.71748429551 117751.2222125363 100330.25474072495 115573.67848408633 105093.11478118367 115048.6876902729 108666.13488670644 115767.8055245109 1.0409286236897821 0.9162589385950828 0.9716839407522385 1.0171327138753223 0.8666507435824424 0.9983231344885131 0.9077922338169645 0.9937882744604177 0.9386559103748333 1.0 16.820874576918953 -4.74384801845639 24.85828013090334 0.9558196501398986 1.0409289035399385 0.23020778272458375 0.04618268809274514 1500.4538630915195 2120165.1583240395 0.010654176350349834 0.32101303266548514 1.8036488181218497e-05 4.74384801845639 0.08510925340003994 QECLDSR ddPTM_PC-9_Lapatinib_30min_R1 2 QECLDSR 7 0 P25786;P25786-2;F5GX11;B4DEV8 P25786 PSMA1 Proteasome subunit alpha type-1;Proteasome subunit alpha type 0 ; 127.02 0.020859 60624000.0 318210.0 350300.0 336140.0 308090.0 351270.0 335880.0 297400.0 269500.0 340740.0 278360.0 False True 313672.2670474336 349488.90187236835 308503.8667379234 330747.96635811194 330608.9892233918 321515.19537452183 312797.9168106243 282021.95385812066 302362.27304873004 326474.15510861465 0.960787437961446 1.0704948505222318 0.9449564748403662 1.0130908103524319 1.0126651192753728 0.9848105595603945 0.9581092773072943 0.8638415918843402 0.9261445915929767 1.0 18.3166092616987 -7.378380682924663 3.061265284404394 0.9202796034653679 1.000672786489578 0.30790605611389943 0.044661292214573246 0.26255754874669646 4.6905579725989375 0.019898358853491806 0.012520327368996326 4.1842663043936997e-08 7.378380682924663 0.08039318302421006 QEDVGFRGNS(ph)PEMR ddPTM_PC-9_Lapatinib_30min_R1 1 QEDVGFRGNSPEMR 14 1 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 QEDVGFRGNS(1)PEMR 117.13 0.00064929 2960000.0 28998.0 9476.8 13938.0 13219.0 10450.0 12871.0 7585.7 8572.4 14452.0 7307.9 True False 28584.483202418076 9454.857051852856 12792.071442235894 14191.16935729129 9835.351545490475 12320.53733376643 7978.450428884836 8970.704999084783 12824.263573693273 8571.060777835335 3.3349994759501906 1.1031139898462752 1.4924723758016096 1.655707470187295 1.1475069189714044 1.4374577025083286 0.930859159173975 1.0466271598823478 1.4962282856349207 1.0 13.065258051918962 -4.7586250045449825 24.99998693501105 1.270017098203382 3.335002246135548 0.8744043300054352 0.23625361474164017 25.794831484307498 229091.70558281604 0.05998804979239495 0.4051450708948807 1.7433115016151873e-05 4.7586250045449825 2.064985147932166 QEEAEEQGAGS(ph)PGQPAHLAR ddPTM_PC-9_AZD4547_30min_R2 2 QEEAEEQGAGSPGQPAHLAR 20 0 Q96S99 Q96S99 PLEKHF1 Pleckstrin homology domain-containing family F member 1 1 QEEAEEQGAGS(1)PGQPAHLAR;QEEAEEQGAGS(1)PGQPAHLAR 140.41 0.00011067 47172000.0 43592.0 53322.0 66195.0 66019.0 61458.0 75925.0 53967.0 76825.0 60404.0 57931.0 True False 57453.349230072796 70557.29373145795 65317.211048955265 50799.3395333823 52925.61754230009 71177.39774754977 58769.958452068066 64953.46151287436 63596.83212278996 55902.85332282404 1.0277355414811307 1.2621411884650757 1.168405674604225 0.9087074543410099 0.9467426865793198 1.2732337173653607 1.0512872771035007 1.1618988593978463 1.1376312360218046 1.0 15.770634300715098 -6.750202543810321 24.9996977193106 1.130333739079259 1.0711362744266049 0.06358371890989434 0.11592670281841867 782.0599145663886 1739921.153074309 0.040747094383513094 0.04040373781516113 1.777450259482454e-07 6.750202543810321 -0.059197464652654075 QEEAEEQGAGS(ph)PGQPAHLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QEEAEEQGAGSPGQPAHLAR 20 0 Q96S99 Q96S99 PLEKHF1 Pleckstrin homology domain-containing family F member 1 1 QEEAEEQGAGS(1)PGQPAHLAR;QEEAEEQGAGS(1)PGQPAHLAR 144.29 4.2817e-05 33084000.0 70944.0 85940.0 93938.0 79305.0 99290.0 75095.0 85345.0 59720.0 75798.0 71986.0 True False 82953.41799212959 94471.55524232624 96177.83818184909 74861.79796027891 79834.83725922872 71156.8860028079 77260.50375570789 58152.41327857037 76906.40235427249 85036.49195913745 0.9755037641015478 1.1109531104331376 1.1310184129898655 0.8803490858518979 0.938830323546175 0.836780591054966 0.9085570438728099 0.6838524489758389 0.904392932756778 1.0 16.37579446163076 -5.773854199368456 23.39917766613611 0.8677627141947156 1.0763378667643615 0.5094593966001871 0.08651025760539066 73.97111440315695 139419.30912134206 0.024204176324750276 0.036240386486477635 1.6832390604829452e-06 5.773854199368456 0.20857515256964587 QEEAEEQGAGS(ph)PGQPAHLAR ddPTM_PC-9_Lapatinib_30min_R1 2 QEEAEEQGAGSPGQPAHLAR 20 0 Q96S99 Q96S99 PLEKHF1 Pleckstrin homology domain-containing family F member 1 1 QEEAEEQGAGS(1)PGQPAHLAR;QEEAEEQGAGS(1)PGQPAHLAR 128.33 4.07e-06 41620000.0 56865.0 79464.0 83981.0 74616.0 76961.0 77401.0 83571.0 82590.0 78829.0 76306.0 True False 56054.09467223619 79280.00599025373 77076.40635603489 80103.50955167916 72434.30529114764 74090.73966054362 87897.89746395654 86427.43290961829 69950.44791382979 89495.39042864618 0.6263349922689883 0.8858557475478351 0.8612332544376928 0.8950573785757706 0.8093635319564176 0.8278721318011956 0.982149997256414 0.9657193794637509 0.7816095061298226 1.0 16.44952575603815 -4.7614248305563365 10.683626976655622 0.8865453349246817 0.6255992499930801 0.5581463592248359 0.07028869308442848 0.05211470445228659 173.24993247463897 0.01740417840689499 0.0980060923887445 1.7321088051967446e-05 4.7614248305563365 -0.26094608493160154 QEEEAAQQGPVVVS(ph)PASDYKDK ddPTM_PC-9_AZD4547_30min_R2 2 QEEEAAQQGPVVVSPASDYKDK 22 1 I3L0X5;I3L4C3;O75391 I3L0X5 SPAG7 Sperm-associated antigen 7 1 QEEEAAQQGPVVVS(0.993)PAS(0.006)DY(0.001)KDK;QEEEAAQQGPVVVS(0.998)PAS(0.001)DY(0.001)KDK 130.25 5.44e-06 59862000.0 148626.0 135683.0 132544.0 124531.0 144847.0 180347.0 147165.0 170334.0 145747.0 144748.0 True False 195885.9763871536 179539.87632432047 130786.37995728874 95822.3019347708 124737.49429121583 169069.87358020936 160262.39990361893 144012.7941859283 153450.88887160225 139680.41657786255 1.4023868283494143 1.2853618332691537 0.9363258154687992 0.686010997693125 0.8930206348696201 1.210404992499175 1.147350529372765 1.0310163565817456 1.0985855614631819 1.0 17.091770241165143 -5.134989443011779 4.193454455180637 0.9997990215922145 1.3764691256976276 0.5009958484312733 0.1388622610409137 0.2071311144374045 5.929304871149527 0.04120278946206302 0.12496839778227657 7.328423471207003e-06 5.134989443011779 0.37667010410541313 QEEEAAQQGPVVVS(ph)PASDYKDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QEEEAAQQGPVVVSPASDYKDK 22 1 I3L0X5;I3L4C3;O75391 I3L0X5 SPAG7 Sperm-associated antigen 7 1 QEEEAAQQGPVVVS(0.995)PAS(0.004)DYKDK;QEEEAAQQGPVVVS(0.928)PAS(0.033)DY(0.039)KDK;QEEEAAQQGPVVVS(1)PASDYKDK;QEEEAAQQGPVVVS(0.98)PAS(0.019)DY(0.001)KDK 141.38 1.3616e-05 38799000.0 167271.0 161443.0 141551.0 184286.0 188955.0 158794.0 177599.0 139130.0 137999.0 130981.0 True False 195586.67654715636 177469.9941003828 144926.1126751571 173961.05288327314 151930.62417481726 150466.56309913946 160775.5370145873 135477.98492042057 140016.9743065414 154726.81845497474 1.2640774139880073 1.1469892283219558 0.9366580022927983 1.1243109282564065 0.9819281860243823 0.9724659538767999 1.039092890424634 0.8755947176658612 0.9049302228578178 1.0 17.239363752016928 -1.5228787452803558 0.4902369270486997 0.9524465063958538 10.28968631739376 0.665619716911766 0.06640690642304227 62.640853836185634 0.6834965940530764 0.03800545619813415 599.3247981455032 0.02999999999999874 1.5228787452803558 9.337239810997907 QEEEAAQQGPVVVS(ph)PASDYKDK ddPTM_PC-9_Lapatinib_30min_R1 2 QEEEAAQQGPVVVSPASDYKDK 22 1 I3L0X5;I3L4C3;O75391 I3L0X5 SPAG7 Sperm-associated antigen 7 1 QEEEAAQQGPVVVS(0.995)PAS(0.004)DY(0.001)KDK;QEEEAAQQGPVVVS(0.994)PAS(0.003)DY(0.003)KDK 85.399 0.00010776 66202000.0 140807.0 174224.0 161302.0 166374.0 187293.0 185385.0 161133.0 141871.0 165154.0 154719.0 True False 138799.06635915852 173820.59503229032 148040.37220372588 178609.69896739422 176276.79397220566 177456.515703542 169475.67831017566 148462.8445855488 146552.61737127998 181461.97299989176 0.7648934047423881 0.957889921280609 0.8158203603562394 0.9842816983341229 0.9714255337249684 0.977926740075993 0.9339459695518507 0.8181485196660865 0.8076216462793965 1.0 17.46930772451777 -4.751445096161396 24.971622790903453 0.9157103117939986 0.7648930942192407 0.2891300727079128 0.07216161608491299 587.4118820883541 1467599.9830810875 0.018803989284837966 0.24942639454276286 1.772372095600397e-05 4.751445096161396 -0.15081721757475797 QEEEDRDS(ph)PGPQVPDPK ddPTM_PC-9_Lapatinib_30min_R1 1 QEEEDRDSPGPQVPDPK 17 1 M0R353;Q6NSJ2-2;Q6NSJ2 M0R353 PHLDB3 Pleckstrin homology-like domain family B member 3 1 QEEEDRDS(1)PGPQVPDPK 53.395 0.029054000000000003 5548000.0 34475.0 25645.0 27355.0 25682.0 28055.0 25433.0 18702.0 20587.0 25560.0 21338.0 True False 33983.380178059284 25585.62057812411 25105.97749335362 27570.739952640513 26404.860058252183 24345.28987721869 19670.298050411202 21543.54717653849 22681.163641267663 25026.2448689022 1.357909680660373 1.0223515638143938 1.0031859603735636 1.1016730674964395 1.0550867777635733 0.9727903648649395 0.7859867971983948 0.860838183650503 0.9062951217843892 1.0 14.611154213706545 -6.840781766908111 2.4518008202817145 0.876602768213318 1.1027566729981095 0.5001030550776786 0.10396825431665865 0.2479482344385559 3.0431967192564544 0.04076956824478688 0.035910543266080674 1.4428401969722523e-07 6.840781766908111 0.22615390478479158 QEEGADAS(ph)EEDPTPAGEEDVKDAR ddPTM_PC-9_AZD4547_30min_R2 1 QEEGADASEEDPTPAGEEDVKDAR 24 1 Q86X53;E5RHA3;H0YB25 Q86X53 ERICH1 Glutamate-rich protein 1 1 QEEGADAS(0.999)EEDPT(0.001)PAGEEDVKDAR 101.22 1.4678e-06 6271400.0 33348.0 29967.0 35797.0 30671.0 34775.0 36219.0 36174.0 38513.0 35980.0 36975.0 True False 43951.970318509535 39653.24671337542 35322.308390655686 23600.27481222629 29947.091510193735 33954.22020439264 39393.41592167639 32561.700790697447 37881.82934537417 35680.51650431412 1.2318199012953 1.1113417236709833 0.9899606802604688 0.6614331047974821 0.8393121637287073 0.9516179565474409 1.1040595759569047 0.9125905110359158 1.0616950945985857 1.0 15.122848879135558 -5.1522341401869545 2.7301708169246517 0.928153599600578 1.2123782224911215 0.4031276491447029 0.11702615490286881 0.3051230707121601 4.21404303718855 0.0340542185072051 0.13043337897397847 7.043132518049198e-06 5.1522341401869545 0.2842246228905435 QEEGADAS(ph)EEDPTPAGEEDVKDAR ddPTM_PC-9_Lapatinib_30min_R1 2 QEEGADASEEDPTPAGEEDVKDAR 24 1 Q86X53;E5RHA3;H0YB25 Q86X53 ERICH1 Glutamate-rich protein 1 1 QEEGADAS(1)EEDPTPAGEEDVKDAR;QEEGADAS(1)EEDPTPAGEEDVKDAR 124.98 6.020300000000001e-09 16321900.0 62324.0 53940.0 60917.0 52279.0 63284.0 51958.0 52277.0 51169.0 55315.0 49557.0 True False 61435.24833117819 53815.10524406371 55908.63940642018 56123.77205763157 59561.75954113103 49735.87746001373 54983.647266674525 53546.498541618406 49084.84220722695 58122.86141944828 1.0569893985057928 0.9258853389151421 0.9619044561992743 0.9656057992845514 1.0247561473496432 0.8557024937415038 0.9459900273986966 0.9212639783027167 0.8445014751252913 1.0 15.826818108914399 -6.755874016178865 24.99999936530788 0.9106017456181992 0.9810454962223382 0.3214872288915197 0.05297806568440471 171.02121753974376 768238.136579317 0.017011878577276065 0.016555138442446486 1.7543893561532954e-07 6.755874016178865 0.07044375060413899 QEESES(ph)PVERPLKENPPNK ddPTM_PC-9_AZD4547_30min_R2 1 QEESESPVERPLKENPPNK 19 2 D6RBF8;H3BLV9;Q96SB4-4;Q96SB4;Q96SB4-3 D6RBF8 SRPK1 SRSF protein kinase 1 1 QEES(0.276)ES(0.724)PVERPLKENPPNK 58.5 0.0076928 12230000.0 51185.0 53347.0 56318.0 51078.0 54776.0 61781.0 56613.0 78253.0 56122.0 57866.0 True False 67460.76528586143 70590.37449255648 55571.1865224725 39302.75624723339 47171.29790258436 57917.82430347556 61651.447326086854 66160.79692505002 59088.494344666185 55840.12895303961 1.2081054709346128 1.264151351654677 0.9951837068500811 0.7038442959235677 0.8447562494394388 1.037207925364629 1.1040706474359048 1.1848252890083737 1.058172598318288 1.0 15.76901465275346 -5.2668783776786405 22.905860067300505 0.9878173493532607 1.236128433609486 0.37136408944861266 0.1275134021721434 153.33469362198858 645767.6267327601 0.03887652001519892 0.08517007615460366 5.409057800988215e-06 5.2668783776786405 0.24831108425622528 QEGPATQVDSAVGTLPAT(ph)SPQSTSVQAK ddPTM_PC-9_AZD4547_30min_R2 1 QEGPATQVDSAVGTLPATSPQSTSVQAK 28 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06 E7ETY2 TCOF1 Treacle protein 1 QEGPATQVDSAVGTLPAT(0.484)S(0.484)PQS(0.004)T(0.022)S(0.006)VQAK 163.31 4.3068999999999996e-13 10301000.0 41328.0 36709.0 52175.0 61349.0 45260.0 57387.0 46942.0 50441.0 45401.0 42809.0 True False 54469.444324198164 48574.46636637961 51483.1254094606 47205.93588260153 38976.43024446779 53798.58181809219 51119.747061296366 42646.50246886943 47800.804172021475 41310.26994004552 1.3185448655564547 1.1758448065548053 1.2462548776413025 1.1427167130864195 0.9435046128005244 1.302305259592136 1.2374585577747992 1.0323462550780524 1.1571167228245134 1.0 15.334212866998206 -1.5228787474340222 0.05243644544124061 0.7420217954028244 1.9435416232680054 0.2783559432407774 0.10333103481361902 674.7582495290688 2.674642962265048 13.933655837224718 64.58658678080872 0.029999999851228736 1.5228787474340222 1.201519827865181 QEGPATQVDSAVGTLPATS(ph)PQSTSVQAK ddPTM_PC-9_AZD4547_30min_R2 1 QEGPATQVDSAVGTLPATSPQSTSVQAK 28 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06 E7ETY2 TCOF1 Treacle protein 1 QEGPATQVDSAVGTLPAT(0.247)S(0.576)PQS(0.024)T(0.115)S(0.038)VQAK 161.41 1.1458e-11 9423600.0 31019.0 32327.0 52548.0 53146.0 47232.0 44560.0 42198.0 45350.0 30574.0 42656.0 True False 40882.3967647189 42776.07056106005 51851.17918574675 40894.01079751485 40674.65208366556 41773.6561558225 45953.54025164206 38342.19953932774 32190.079221941898 41162.62642347591 0.9931921336633371 1.0391968219176597 1.2596664423768387 0.9934742836086897 0.9881452088409003 1.014844284377299 1.1163898964773975 0.9314808813428965 0.7820219946796986 1.0 15.329047417350738 -7.91509233349985 5.516114690796416 0.8801928010421695 1.0574661271295522 0.3740670052539229 0.09150352047409038 0.20024607343835607 9.815826561939426 0.05247321428510521 0.024468708154785853 1.215927460005896e-08 7.91509233349985 0.17727332608738278 QEGPATQVDSAVGTLPATS(ph)PQSTSVQAK ddPTM_PC-9_Lapatinib_30min_R1 2 QEGPATQVDSAVGTLPATSPQSTSVQAK 28 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06 E7ETY2 TCOF1 Treacle protein 1 QEGPATQVDSAVGTLPAT(0.344)S(0.644)PQS(0.002)T(0.008)S(0.003)VQAK;QEGPATQVDSAVGTLPAT(0.268)S(0.574)PQS(0.02)T(0.106)S(0.032)VQAK 176.2 2.9366000000000002e-18 20766500.0 100091.0 81079.0 106016.0 72544.0 91056.0 90926.0 75624.0 69917.0 97146.0 73539.0 True False 98663.68398555851 80891.26655697898 97299.77371359465 77879.12775968965 85700.26510298387 87037.30693885841 79539.44068892613 73165.59906455742 86204.39448726871 86250.11816544189 1.1439252036305083 0.9378684722705684 1.1281117728668812 0.9029451717423123 0.9936249007635757 1.009126813854406 0.9221951503458398 0.8482956385545326 0.9994698711242868 1.0 16.39623881286768 -1.5228787537624016 0.43807930568865133 0.9432228156875765 4.362767200578431 0.2983196814781284 0.07411761188528304 104.6221597837701 1.293322812886737 0.04651033880216965 317.51744136969455 0.029999999414079784 1.5228787537624016 3.4195443848908544 QEGPATQVDSAVGTLPATSPQST(ph)SVQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QEGPATQVDSAVGTLPATSPQSTSVQAK 28 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06 E7ETY2 TCOF1 Treacle protein 1 QEGPATQVDSAVGTLPAT(0.07)S(0.133)PQS(0.033)T(0.555)S(0.208)VQAK 128.26 1.614e-10 7246700.0 17452.0 17973.0 19273.0 19020.0 20634.0 21243.0 22755.0 16551.0 18286.0 15873.0 True False 20406.278907288048 19757.240660581036 19732.541413259518 17954.371063671984 16590.91582240837 20128.97968383576 20599.481668066488 16116.553787234065 18553.39815628676 18750.649249401147 1.0882971909860548 1.0536830164007274 1.052365768822097 0.9575333005733337 0.8848182055849744 1.073508411154277 1.0986009814419833 0.8595197730419276 0.9894803059621688 1.0 14.194652929967294 -5.6725171402843255 5.488967550387134 0.9795916630723439 1.0662444802565392 0.23811553755572867 0.06935119848709326 0.32504662879246493 15.569041846991027 0.020075990041879578 0.035119232781692114 2.125606452330035e-06 5.6725171402843255 0.08665281718419526 QEILAALEK ddPTM_PC-9_Lapatinib_30min_R1 1 QEILAALEK 9 0 C9JIZ6;P07602;P07602-2;P07602-3;Q5BJH1 C9JIZ6 PSAP Prosaposin;Saposin-A;Saposin-B-Val;Saposin-B;Saposin-C;Saposin-D 0 133.81 0.005303 6747100.0 61210.0 67732.0 74316.0 58938.0 72965.0 62325.0 58594.0 66861.0 63134.0 68289.0 False True 60337.13417546076 67575.17071544164 68206.02534805592 63272.497131404416 68673.3421547093 59659.5050366711 61627.710617356126 69967.60614808065 56023.18408950673 80092.6626606272 0.7533415942372199 0.8437123760234401 0.8515889356439807 0.7899911805842432 0.8574236374896856 0.7448810297325669 0.7694551357155932 0.873583220032914 0.6994796056024642 1.0 16.2893824620338 -10.781434168911009 4.863779016483571 1.0000489331062845 0.8023825194236596 0.550834738373897 0.05455886188169031 2.751996590683051e-05 4.195179167698559e-06 0.05021748129862881 0.012176516821829289 1.6541154993821797e-11 10.781434168911009 -0.19766641368262494 QEKPAEKPAETPVAT(ph)SPTATDSTSGDSSR ddPTM_PC-9_AZD4547_30min_R2 4 QEKPAEKPAETPVATSPTATDSTSGDSSR 29 2 P54727;H0Y579;P54727-2 P54727 RAD23B UV excision repair protein RAD23 homolog B 1 QEKPAEKPAET(0.003)PVAT(0.907)S(0.069)PT(0.014)AT(0.007)DSTSGDSSR;QEKPAEKPAET(0.003)PVAT(0.483)S(0.483)PT(0.027)AT(0.004)DSTSGDSSR;QEKPAEKPAETPVAT(0.482)S(0.482)PT(0.019)AT(0.011)DS(0.002)T(0.002)S(0.001)GDSSR;QEKPAEKPAETPVAT(0.496)S(0.496)PT(0.005)AT(0.002)DSTSGDSSR 108.5 1.5121000000000001e-10 461497100.0 180684.0 175821.0 226312.0 273871.0 240123.0 254111.0 194881.0 280398.0 203805.0 219829.0 True False 238137.75353932992 232651.6998829504 223310.955010366 210734.27221477067 206786.06627468675 238221.39899937614 212225.03146547888 237068.93200503648 214577.71622384602 212132.85362073992 1.1225878004030563 1.0967263953319317 1.0526938717828722 0.9934070494876306 0.9747951000762363 1.1229821073603168 1.0004345288490946 1.1175493468299744 1.0115251483274585 1.0 17.694608546909308 -5.222396880937356 2.8886208051499698 1.0359265913555602 1.1170430609624267 0.292559469312872 0.04805233497837687 0.35757581921308923 5.833313830157657 0.012788241085635664 0.041518465575151604 5.992432062770908e-06 5.222396880937356 0.08111646960686647 QEKPAEKPAETPVAT(ph)SPTATDSTSGDSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 QEKPAEKPAETPVATSPTATDSTSGDSSR 29 2 P54727;H0Y579;P54727-2 P54727 RAD23B UV excision repair protein RAD23 homolog B 1 QEKPAEKPAET(0.024)PVAT(0.422)S(0.422)PT(0.098)AT(0.03)DS(0.001)T(0.002)SGDSSR;QEKPAEKPAET(0.005)PVAT(0.431)S(0.431)PT(0.095)AT(0.028)DS(0.007)T(0.002)S(0.001)GDSSR;QEKPAEKPAETPVAT(0.481)S(0.481)PT(0.025)AT(0.009)DS(0.001)T(0.001)SGDSSR;QEKPAEKPAETPVAT(0.532)S(0.374)PT(0.064)AT(0.027)DS(0.001)TSGDSSR;QEKPAEKPAET(0.02)PVAT(0.462)S(0.462)PT(0.035)AT(0.017)DS(0.002)T(0.001)S(0.001)GDSSR;QEKPAEKPAET(0.005)PVAT(0.469)S(0.469)PT(0.046)AT(0.007)DS(0.002)T(0.001)SGDSSR 136.3 3.058e-12 998609000.0 123845.0 117168.0 124521.0 145462.0 169833.0 165805.0 173104.0 161887.0 159285.0 140140.0 True False 144809.51244975274 128799.66470366433 127490.05288852198 137312.235734167 136555.4428063913 157109.89391697905 156706.33595556938 157637.637783455 161614.2417873856 165546.2726523702 0.874737377831741 0.7780281768960762 0.7701173263878778 0.8294492744183272 0.8248777856396889 0.9490391502011849 0.9466014150897631 0.9522270435799995 0.9762481462011444 1.0 17.336875002619756 -6.75784242108072 3.2527192862153886 0.9637551964892652 0.8087312826958257 0.8592188842363286 0.030285104188033193 0.08838070475344073 1.9465236103008197 0.011135069955288927 0.010392918361484154 1.7464557199930014e-07 6.75784242108072 -0.1550239137934395 QEKPAEKPAETPVAT(ph)SPTATDSTSGDSSR ddPTM_PC-9_Lapatinib_30min_R1 5 QEKPAEKPAETPVATSPTATDSTSGDSSR 29 2 P54727;H0Y579;P54727-2 P54727 RAD23B UV excision repair protein RAD23 homolog B 1 QEKPAEKPAETPVAT(0.422)S(0.422)PT(0.083)AT(0.048)DS(0.02)T(0.002)S(0.002)GDSSR;QEKPAEKPAET(0.006)PVAT(0.434)S(0.434)PT(0.108)AT(0.016)DSTSGDSSR;QEKPAEKPAET(0.003)PVAT(0.647)S(0.223)PT(0.1)AT(0.018)DS(0.003)T(0.004)S(0.002)GDS(0.001)SR;QEKPAEKPAET(0.001)PVAT(0.758)S(0.233)PT(0.007)ATDSTSGDSSR;QEKPAEKPAET(0.001)PVAT(0.43)S(0.43)PT(0.104)AT(0.036)DSTSGDSSR 114.68 3.058e-12 1130728100.0 445882.0 346812.0 371620.0 339960.0 385990.0 445101.0 373927.0 411489.0 457218.0 329506.0 True False 439523.64091525483 346008.9781220657 341066.83809468336 364961.7924733141 363286.8270855381 426065.06781110796 393287.1104211375 430608.2811544501 405721.29412101436 386460.6730608537 1.1373049615479132 0.8953277842777594 0.8825395748378713 0.9443698102131228 0.9400356942097793 1.1024797541146394 1.0176639897307451 1.114235706686369 1.049838502085121 1.0 18.55996208479185 -6.75181333597618 24.996121535487656 1.0615345979452209 0.9511650172254842 0.30279329370130703 0.0727648418678182 226.67267806725147 588604.5591743524 0.02388141318488407 0.023591527540444593 1.7708699320176405e-07 6.75181333597618 -0.11036958071973668 QEKPAEKPAETPVATS(ph)PTATDSTSGDSSR ddPTM_PC-9_AZD4547_30min_R2 6 QEKPAEKPAETPVATSPTATDSTSGDSSR 29 2 P54727;H0Y579;P54727-2 P54727 RAD23B UV excision repair protein RAD23 homolog B 1 QEKPAEKPAET(0.001)PVAT(0.244)S(0.632)PT(0.08)AT(0.027)DS(0.004)T(0.005)S(0.006)GDS(0.001)S(0.001)R;QEKPAEKPAETPVAT(0.028)S(0.964)PT(0.005)AT(0.002)DSTSGDSSR;QEKPAEKPAETPVAT(0.33)S(0.462)PT(0.127)AT(0.074)DS(0.006)T(0.001)SGDSSR;QEKPAEKPAET(0.001)PVAT(0.176)S(0.745)PT(0.04)AT(0.024)DS(0.004)T(0.004)S(0.004)GDS(0.001)S(0.001)R;QEKPAEKPAETPVAT(0.052)S(0.585)PT(0.315)AT(0.035)DS(0.003)T(0.003)S(0.003)GDS(0.002)S(0.002)R;QEKPAEKPAETPVAT(0.079)S(0.889)PT(0.016)AT(0.01)DS(0.002)T(0.002)S(0.001)GDSSR 102.55 3.4303e-11 2702466000.0 669631.0 676109.0 795027.0 1015689.0 966501.0 904206.0 761482.0 850725.0 792912.0 838716.0 True False 882559.7288099398 894648.0122178901 784484.4225185856 781537.5932886213 832319.0191716378 847665.8558804239 829252.4228138985 719264.9989657004 834823.7095580685 809352.8081252833 1.0904511851317682 1.105386925499372 0.9692737390208099 0.9656327690996824 1.0283760194760447 1.047337882034271 1.0245870706678697 0.8886915468073129 1.0314707024885523 1.0 19.626409205000243 -5.25569921361941 24.66534348311367 0.9935976592163825 1.0979190704360131 0.4738598359030689 0.04361624436364211 337.5495202154297 1450427.3980787673 0.011631678506747217 0.02900235906028101 5.550099721438565e-06 5.25569921361941 0.10432141121963057 QEKPAEKPAETPVATS(ph)PTATDSTSGDSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 QEKPAEKPAETPVATSPTATDSTSGDSSR 29 2 P54727;H0Y579;P54727-2 P54727 RAD23B UV excision repair protein RAD23 homolog B 1 QEKPAEKPAETPVAT(0.228)S(0.585)PT(0.111)AT(0.066)DS(0.006)T(0.003)S(0.001)GDSSR;QEKPAEKPAET(0.002)PVAT(0.36)S(0.431)PT(0.122)AT(0.054)DS(0.013)T(0.013)S(0.004)GDS(0.001)SR;QEKPAEKPAETPVAT(0.363)S(0.612)PT(0.016)AT(0.008)DSTSGDSSR;QEKPAEKPAET(0.001)PVAT(0.296)S(0.651)PT(0.03)AT(0.019)DS(0.002)T(0.001)SGDSSR;QEKPAEKPAET(0.001)PVAT(0.112)S(0.669)PT(0.154)AT(0.05)DS(0.005)T(0.005)S(0.002)GDS(0.001)SR;QEKPAEKPAET(0.001)PVAT(0.066)S(0.915)PT(0.018)AT(0.001)DSTSGDSSR;QEKPAEKPAETPVAT(0.083)S(0.895)PT(0.019)AT(0.002)DSTSGDSSR 80.538 7.0232e-07 1393562500.0 509396.1 653148.8 522786.4 683408.8 731546.0 673262.0 728671.0 672948.0 632694.3 572867.6 True False 595626.7986984173 717989.096353959 535251.6104544632 645119.6205772234 588204.8127469013 637954.9555099864 659646.0077588065 655283.8280473443 641946.2571974811 676723.9610625721 0.8801621236570101 1.0609777954760071 0.790945261660348 0.9532980324271 0.8691946001488101 0.942710753891865 0.9747637821528436 0.9683177569454419 0.9486087299015037 1.0 19.36820794602574 -6.998242961600749 24.881446508887805 0.9686330838472329 0.914042990677902 0.16446842395010797 0.06547188740892133 110.21560494598572 1560734.171887762 0.022282438917031022 0.019516987763977763 1.0040539254411545e-07 6.998242961600749 -0.054590093169330944 QEKPAEKPAETPVATS(ph)PTATDSTSGDSSR ddPTM_PC-9_Lapatinib_30min_R1 4 QEKPAEKPAETPVATSPTATDSTSGDSSR 29 2 P54727;H0Y579;P54727-2 P54727 RAD23B UV excision repair protein RAD23 homolog B 1 QEKPAEKPAET(0.005)PVAT(0.177)S(0.754)PT(0.053)AT(0.01)DS(0.001)TSGDSSR;QEKPAEKPAET(0.002)PVAT(0.382)S(0.527)PT(0.059)AT(0.02)DS(0.003)T(0.003)S(0.004)GDS(0.001)S(0.001)R;QEKPAEKPAETPVAT(0.315)S(0.571)PT(0.082)AT(0.03)DS(0.001)TSGDSSR;QEKPAEKPAETPVAT(0.255)S(0.699)PT(0.016)AT(0.027)DS(0.001)TSGDSSR 117.26 7.7592e-13 1395289500.0 520254.0 455963.0 419187.0 381854.0 470788.0 471535.0 463937.0 492401.0 521360.0 427219.0 True False 512835.0825571014 454907.24568778253 384723.06296861306 409936.81698760175 443097.1754448208 451368.54725177196 487957.387798825 515279.7480582282 462638.9466358101 501063.2349164663 1.023493736559214 0.9078839036426639 0.7678133939177385 0.8181338969240949 0.8843138840922758 0.9008215247063994 0.9738439258673085 1.0283726926086125 0.9233144928562519 1.0 18.93463315958096 -7.17889671678612 2.736321621141606 0.9856562448038279 0.8729813004286912 0.34327968304582346 0.0663391151177095 0.33256241242286383 4.862906348468304 0.031183720539886505 0.022352944448621088 6.623740096917687e-08 7.17889671678612 -0.1126749443751367 QEKPAEKPAETPVATSPT(ph)ATDSTSGDSSR ddPTM_PC-9_AZD4547_30min_R2 1 QEKPAEKPAETPVATSPTATDSTSGDSSR 29 2 P54727;H0Y579;P54727-2 P54727 RAD23B UV excision repair protein RAD23 homolog B 1 QEKPAEKPAETPVAT(0.003)S(0.042)PT(0.691)AT(0.217)DS(0.011)T(0.011)S(0.024)GDSSR 73.968 3.4492000000000004e-06 19620000.0 25548.0 57856.0 34405.0 49427.0 37375.0 39717.0 28082.0 39731.0 38639.0 36335.0 True False 33671.73256858827 76556.82056425558 33948.76722017237 38032.368789537635 32186.126389460536 37233.4897114184 30581.243597957553 33591.48687755301 40681.378656918074 35062.92270951327 0.9603230411665727 2.1834124096986414 0.9682241124457487 1.0846890632770525 0.9179533222633435 1.0619049079247525 0.8721818158547363 0.9580344215982592 1.1602392360144127 1.0 15.09765863813341 -5.373044040413169 22.34168987032662 0.9987137108752352 1.5733080944766398 0.3897923015262107 0.28470823177438953 8.273958248651418 1640.489395259649 0.06725004989652915 0.13999217966600275 4.236000079506563e-06 5.373044040413169 0.5745943836014046 QEKPAEKPAETPVATSPT(ph)ATDSTSGDSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QEKPAEKPAETPVATSPTATDSTSGDSSR 29 2 P54727;H0Y579;P54727-2 P54727 RAD23B UV excision repair protein RAD23 homolog B 1 QEKPAEKPAETPVAT(0.148)S(0.331)PT(0.472)AT(0.047)DS(0.001)TSGDSSR 101.41 5.4064e-10 165170000.0 174780.0 163620.0 153580.0 187870.0 216060.0 226540.0 232830.0 197950.0 270620.0 187560.0 True False 204366.8019376463 179863.1122730909 157241.9296553936 177344.2529827583 173724.59399968735 214659.84359912216 210774.6568567747 192754.02224536226 274577.305537259 221563.14327585642 0.922386272897384 0.8117916617979777 0.7096935317424166 0.8004230774157075 0.7840861590566629 0.9688427435417842 0.9513073958981998 0.8699733150354098 1.2392733803897946 1.0 17.757358385446977 -7.431945319354892 0.931082000700947 1.0729063626509585 0.8008999573285316 0.5211668975058343 0.09807937539366417 0.4707812670509196 0.7654313369665052 0.07902204473877798 0.04008354413858691 3.698747466085768e-08 7.431945319354892 -0.2720064053224269 QELANSSDATLPDRPLS(ph)PPLTAPPTMK ddPTM_PC-9_AZD4547_30min_R2 1 QELANSSDATLPDRPLSPPLTAPPTMK 27 1 A0A1B0GV05;Q684P5-3;Q684P5-2;Q684P5 A0A1B0GV05 RAP1GAP2 Rap1 GTPase-activating protein 2 1 QELANS(0.001)S(0.001)DAT(0.002)LPDRPLS(0.599)PPLT(0.346)APPT(0.051)MK 51.22 0.023267 9468400.0 21461.0 15008.0 24507.0 29426.0 29001.0 27564.0 23342.0 29599.0 25707.0 26104.0 True False 28285.151583469244 19859.042502564076 24182.021167410665 22642.290327168026 24974.711743698877 25840.41872260082 25419.39278055428 25025.154667355248 27065.81953811936 25190.10690543923 1.1228674689491576 0.7883667416383997 0.9599808868690871 0.8988564602827843 0.9914492160533928 1.0258161594789093 1.0091022192154946 0.9934517055166462 1.0744622736108798 1.0 14.62056962435363 -6.45682954866608 4.746171419543253 1.0186861139483585 0.9330873433142818 0.1723483034886799 0.07945985388390955 0.3443437704614274 15.159575088569914 0.023920341570102376 0.02671018882739219 3.4927737251014387e-07 6.45682954866608 -0.08559877063407673 QELANSSDATLPDRPLSPPLT(ph)APPTMK ddPTM_PC-9_Lapatinib_30min_R1 1 QELANSSDATLPDRPLSPPLTAPPTMK 27 1 A0A1B0GV05;Q684P5-3;Q684P5-2;Q684P5 A0A1B0GV05 RAP1GAP2 Rap1 GTPase-activating protein 2 1 QELANSSDATLPDRPLS(0.412)PPLT(0.56)APPT(0.028)MK 58.318999999999996 0.0018184000000000002 5777700.0 19375.0 26636.0 30685.0 31967.0 32013.0 39758.0 28448.0 24472.0 42332.0 28443.0 True False 19098.708947060164 26574.325978510977 28162.197747525363 34317.9598187859 30130.05827997961 38057.643020424664 29920.898242866944 25609.058459428277 37564.12438427787 33359.334652084784 0.5725146843079076 0.7966083932927067 0.84420741724132 1.0287363395193256 0.903197218835917 1.1408393907534442 0.8969273085006522 0.7676729385197089 1.1260453715892775 1.0 15.025802894239995 -4.704455446092873 1.1076216864534847 0.9707092985403376 0.3357247015990249 0.5780791689221598 0.1074543321792847 1.4442344658033677 1.3126260824797624 0.033635514743128404 1.1213514910387465 1.974897472094705e-05 4.704455446092873 -0.6349845969413127 QELGS(ph)PEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QELGSPEER 9 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF0 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 QELGS(1)PEER 76.24 0.024803 28541000.0 35098.0 40479.0 51851.0 42274.0 46447.0 40168.0 44552.0 42670.0 45392.0 32496.0 True False 41039.398182901445 44497.4876036087 53087.32448601255 39905.524834157186 37346.043772579316 38061.519368277324 40331.71203145233 41549.95771260214 46055.77212677287 38387.26756180553 1.0690888096378792 1.1591730912330604 1.3829409556316856 1.0395510639017789 0.9728758034796359 0.9915141604438572 1.0506533700664196 1.0823890407334804 1.1997668771975145 1.0 15.22834025113495 QELSHALYQHDAACR ddPTM_PC-9_AZD4547_30min_R2 2 QELSHALYQHDAACR 15 0 F5H2I0;F5GY56;Q9UMS4 F5H2I0 PRPF19 Pre-mRNA-processing factor 19 0 ; 164.66 0.00012663 10817700.0 23533.0 17011.4 36011.0 52595.0 36131.0 32086.0 31875.0 49381.0 32095.0 31768.0 False True 31016.004483191933 22510.0023739418 35533.470610830605 40470.03533464972 31114.834316457498 30079.657347749588 34711.81324994294 41750.301112492634 33791.47617675888 30655.811989426653 1.0117495662450406 0.734281720598548 1.1591104037004887 1.3201423387058886 1.0149734193042796 0.9812056962681078 1.1323077419027499 1.3619049179611529 1.1022861240280875 1.0 14.903872997786234 -5.278693158575932 24.7667327507432 1.143797373771045 0.873015648323168 0.3716234631396027 0.135263336102552 642.9105147670107 922857.895629249 0.03629483501636911 0.07584847433534538 5.2638904389533686e-06 5.278693158575932 -0.27078172544787693 QELSHALYQHDAACR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QELSHALYQHDAACR 15 0 F5H2I0;F5GY56;Q9UMS4 F5H2I0 PRPF19 Pre-mRNA-processing factor 19 0 127.07 9.177e-06 3909200.0 12981.0 11080.0 14667.0 14191.0 17289.0 14151.0 14653.0 18938.0 16147.0 11068.0 False True 15178.426913563273 12179.949174831008 15016.716904907244 13395.924277842762 13901.344560124951 13408.896648588241 13264.961761466851 18440.89756646962 16383.1193278772 13074.540785760211 1.1609147244463418 0.9315775884149198 1.1485464117609623 1.024580862712408 1.0632376913203125 1.0255730482857328 1.0145642572712024 1.4104432322819347 1.2530550476939457 1.0 13.674472655448753 -7.735407535207074 24.999916627176656 1.248811996597682 1.0500191604341684 0.3111100008610945 0.11258796742081352 200.93356818579227 192968.5910548258 0.04930666445732057 0.02845558463438979 1.8390454597748915e-08 7.735407535207074 -0.19879283616351362 QELSHALYQHDAACR ddPTM_PC-9_Lapatinib_30min_R1 2 QELSHALYQHDAACR 15 0 F5H2I0;F5GY56;Q9UMS4 F5H2I0 PRPF19 Pre-mRNA-processing factor 19 0 ; 138.01 6.7092999999999994e-06 14968900.0 66988.0 74274.0 109800.0 83989.0 76492.0 92444.0 61255.0 68380.0 99124.0 67728.0 False True 66032.73883590531 74102.02311638102 100772.66784025687 90165.83123909052 71992.89094905823 88490.38561748924 64426.48417698313 71557.1844334631 87959.61129800534 79434.69455811281 0.831283347953168 0.9328672254435307 1.2686228404457907 1.1350938244387285 0.9063154500630665 1.1140017105844282 0.8110622761928042 0.9008303592218552 1.1073198151930437 1.0 16.277481648056416 -7.234772942625713 24.98549901477526 0.9465389013253092 1.0367023775834903 0.06737749454012743 0.1373224056209647 2035.505683443219 1907198.6558890603 0.05525325096135182 0.042786296285196194 5.8240763191939776e-08 7.234772942625713 0.09016347625818111 QEMEKMTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QEMEKMTK 8 1 P40222;Q9NUQ3;Q9NUQ3-2 P40222;Q9NUQ3 TXLNA;TXLNG Alpha-taxilin;Gamma-taxilin 0 84.49799999999999 0.008180199999999999 10102000.0 31637.0 33524.0 26428.0 47792.0 32085.0 49590.0 43885.0 38223.0 56842.0 42113.0 False True 36992.51924076736 36852.041167602416 27058.14374874814 45114.369183754585 25798.17457409967 46989.41310179426 39727.89510011417 37219.68675061614 57673.20671550103 49747.75353367539 0.7436018033603523 0.7407779959884304 0.5439068465761346 0.9068624405967525 0.518579689364994 0.94455346752464 0.7985867155432747 0.7481681906585246 1.1593127853795593 1.0 15.602343758693147 -8.252189458073179 24.192408325396467 1.079656392999095 0.7429459340324795 0.5111576447873336 0.13163950075511174 286.6435775137709 749700.0607860122 0.08764010852647534 0.032053657744088124 5.5951346422771446e-09 8.252189458073179 -0.33671045896661544 QEMQEVQS(ph)SR ddPTM_PC-9_AZD4547_30min_R2 1 QEMQEVQSSR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 QEMQEVQS(0.96)S(0.04)R 71.806 0.028363 5492100.0 36690.0 48097.0 48459.0 69185.0 60842.0 53241.0 31665.0 52918.0 45207.0 37491.0 True False 48356.65680059115 63643.41466190201 47816.40199745189 53235.46714759462 52395.13850936609 49911.831853504176 34483.123656766824 44740.73903466689 47596.54972808031 36178.45150137228 1.3366148852102457 1.7591525347481487 1.3216818302916633 1.4714689252406328 1.448241600594174 1.3796011101141512 0.9531398450113004 1.2366681595802915 1.3156049458411712 1.0 15.142843039053654 -7.0629139521937745 5.885509657464096 1.146124884576853 1.470604854896448 0.5423079119983784 0.14821640518364704 0.179988032173267 12.48454563239966 0.055859186520133705 0.04359046128994375 8.651393139207214e-08 7.0629139521937745 0.3244799703195951 QEMQEVQS(ph)SR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QEMQEVQSSR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 QEMQEVQS(0.867)S(0.133)R 71.806 0.028363 7611600.0 32019.0 49480.0 51291.0 44166.0 58822.0 51091.0 55319.0 49567.0 40145.0 31480.0 True False 37439.184295923485 54392.047398072056 52513.97196220068 41691.522208103925 47296.251357260146 48411.69801943478 50078.78384512284 48265.91877057764 40732.044678121616 37187.07480445711 1.0067794924121367 1.4626600151822864 1.4121565688707127 1.1211293823817228 1.2718465113473079 1.301842058672287 1.3466717699215367 1.2979218995948738 1.095328010936736 1.0 15.182513647233646 -8.40497349096403 3.2611395354528394 1.0035306037811773 1.2862085512202435 0.35879391648925996 0.12537351027136848 0.24402518352700076 4.728643330682075 0.11752823780407898 0.031423646268298924 3.935740982144071e-09 8.40497349096403 0.28267794743906616 QEMQEVQSS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 QEMQEVQSSR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 QEMQEVQS(0.351)S(0.649)R 73.219 0.028526 4287100.0 23132.0 26550.0 25450.0 41370.0 36461.0 26960.0 19109.0 28035.0 25899.0 21225.0 True False 30487.49482451009 35131.768286452316 25112.516371265418 31832.785660128513 31399.019512672137 25274.18693808292 20809.66398096187 23702.834930210636 27267.968266143573 20481.919210387205 1.4885077180193473 1.715257634091027 1.2260821905073158 1.5541895919589814 1.5330115889114744 1.233975521457255 1.0160016630867508 1.1572565386445806 1.3313190031681645 1.0 14.322063285589529 -6.86445596044601 4.23265525855146 1.13774149751091 1.5025945689071865 0.6197265480416693 0.14091560181670895 0.15310372381748244 4.935484245854127 0.050948590715430356 0.04502416621111937 1.3662936174249424e-07 6.86445596044601 0.36485307139627654 QEMQEVQSSR ddPTM_PC-9_AZD4547_30min_R2 1 QEMQEVQSSR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 130.41 0.0028558000000000004 10206000.0 4605.4 3717.8 11704.0 17487.0 10175.0 5695.4 6095.0 13013.0 5185.3 7039.3 False True 6069.821401729152 4919.506144458473 11548.797312742254 13455.642321456788 8762.37688328457 5339.265737654207 6637.443192420459 11002.139858991653 5459.384372000245 6792.856249596161 0.8935595246977301 0.7242176138720644 1.7001386292296168 1.9808519166376783 1.2899399842011228 0.7860118838775116 0.9771211031905848 1.6196632837101088 0.8036949659172912 1.0 12.729802608863217 -6.545993756690059 24.685547411717963 1.0684559989868105 1.349465755948402 0.10705337552696881 0.3983888200428821 546.0518501614813 583148.3236150291 0.14424045768728985 0.14424895257786358 2.844501999010432e-07 6.545993756690059 0.2810097569615915 QEMQEVQSSR ddPTM_PC-9_Lapatinib_30min_R1 5 QEMQEVQSSR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;;;; 202.96 0.00042961 45527400.0 107883.0 104002.1 129341.0 100237.79999999999 101231.0 95351.0 93946.0 91933.0 104858.0 85936.4 False True 106344.56863668097 103761.28952731998 118707.08225069813 107609.6221954982 95276.79160780358 91273.06000403732 98810.0641986916 96204.54279791679 93047.78783630849 100790.3922369447 1.0551062088009258 1.0294759969123952 1.1777618840061035 1.0676575396444774 0.9452963669773268 0.9055730211810924 0.9803520157596212 0.9545011251841625 0.9231811264070252 1.0 16.620998596084753 -6.226798811517169 5.1317404656383685 0.9480725402691854 1.0870813821807146 0.6854666517542691 0.04351327198501437 0.11318129501531984 7.996606328636925 0.013315950333244 0.016910696822665452 5.93200063003871e-07 6.226798811517169 0.13900884191152918 QENAETPARS(ph)PGEDASPGAGHEQEAFLGVR ddPTM_PC-9_AZD4547_30min_R2 1 QENAETPARSPGEDASPGAGHEQEAFLGVR 30 1 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 QENAET(0.02)PARS(0.979)PGEDAS(0.002)PGAGHEQEAFLGVR 89.186 2.817e-09 2984300.0 13179.0 12412.0 14896.0 25791.0 21824.0 17056.0 16909.0 20729.0 17610.0 20033.0 True False 17369.64785977081 16423.93627011097 14698.46930712651 19845.28341697786 18794.114309661196 15989.485623736742 18413.868242926586 17525.8093550325 18540.828648472456 19331.650767570627 0.8985082582243245 0.849587884013639 0.7603318249356953 1.0265695183294365 0.9721939701698334 0.8271143430006268 0.952524358334486 0.9065862799690404 0.95909184742646 1.0 14.238677216917642 -1.5228787454089185 0.07581443983949811 1.0842012486463022 0.48015504108723306 0.22206932940359236 0.06976370763531894 352.614189080717 1.9672708997212278 2.5162237611333564 22.46007500378145 0.02999999999111794 1.5228787454089185 -0.6040462075590691 QENAETPARS(ph)PGEDASPGAGHEQEAFLGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QENAETPARSPGEDASPGAGHEQEAFLGVR 30 1 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 QENAET(0.349)PARS(0.651)PGEDAS(0.001)PGAGHEQEAFLGVR 66.437 6.044e-05 4392500.0 4760.6 3758.8 3309.9 5568.7 6843.5 5406.8 4042.8 5996.7 2701.1 3987.6 True False 5566.475553864061 4131.94882295621 3388.8205688656526 5256.703792968989 5502.565301475799 5123.257889872583 3659.8367166626767 5839.292979028855 2740.5984775208435 4710.520314175766 1.1817113997178608 0.8771746107370747 0.7194153390374709 1.1159497130602636 1.1681438428184814 1.087620379102226 0.7769495666219338 1.2396280218676012 0.5818037700152422 1.0 12.201670710364622 -8.265028059271323 24.99988546040141 0.7909019293224314 1.008167733393452 0.18431205642011284 0.19200426732069928 578.9310576396197 4032923.9919553404 0.15949632469794184 0.04751444732191025 5.4321523384171405e-09 8.265028059271323 0.21726580407102059 QENAETPARS(ph)PGEDASPGAGHEQEAFLGVR ddPTM_PC-9_Lapatinib_30min_R1 2 QENAETPARSPGEDASPGAGHEQEAFLGVR 30 1 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 QENAET(0.067)PARS(0.894)PGEDAS(0.039)PGAGHEQEAFLGVR;QENAET(0.35)PARS(0.562)PGEDAS(0.089)PGAGHEQEAFLGVR 74.525 1.103e-06 4632300.0 17330.0 15881.8 20860.4 15058.2 21350.0 20799.0 17016.800000000003 16033.0 22225.0 16911.4 True False 17082.871022067222 15845.026667874883 19145.338435472637 16165.63026068264 20094.234975715008 19909.475254837093 17897.84664015814 16777.951711344125 19721.78646037456 19834.512956975952 0.8612700024004897 0.7988613938867637 0.9652537713934172 0.8150253195401534 1.013094449019365 1.0037793868709428 0.9023587662062218 0.8458968338541023 0.9943166491233784 1.0 14.275725351613819 -5.537669892846343 1.1814925086164705 0.9451998360508798 0.8290958944843903 0.2731882843560536 0.0685228178128224 0.8825423225686739 2.1769145065310296 0.023753253073314735 0.0913625959228549 2.8995466951997575e-06 5.537669892846343 -0.11610394156648951 QENCGAQQVPAGPGT(ph)S(ph)TPPSSPVR ddPTM_PC-9_AZD4547_30min_R2 1 QENCGAQQVPAGPGTSTPPSSPVR 24 0 Q96G46-2;Q96G46 Q96G46-2 DUS3L tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like 2 QENCGAQQVPAGPGT(0.509)S(0.509)T(0.509)PPS(0.237)S(0.237)PVR 73.404 0.0030364999999999997 0.0 3662.0 1935.2 3978.0 7726.6 5454.3 5332.7 4250.5 6040.0 5987.0 6264.8 True False 4826.43982566816 2560.715555101414 3925.2491208209735 5945.35174478001 4697.064593071161 4999.245425990904 4628.786265690426 5106.6567853922725 6303.460597297252 6045.471258856712 0.7983562602497446 0.4235758380870515 0.6492875332209083 0.9834389231559038 0.7769559049991158 0.8269405662407094 0.7656617768067594 0.8447078096535384 1.0426748101833387 1.0 12.561639090028235 -5.383817260154666 0.23493600130177145 1.02795263943172 0.3553157628475924 0.4191946689371536 0.13203190477496082 8.35951840950116 0.5202680219118798 0.23861154979975038 1.6302799690386998 4.132213382281629e-06 5.383817260154666 -0.6726368765841275 QENEDSS(ph)DATTPVPR ddPTM_PC-9_Lapatinib_30min_R1 1 QENEDSSDATTPVPR 15 0 Q6P4R8-3;Q6P4R8;Q6P4R8-2 Q6P4R8-3 NFRKB Nuclear factor related to kappa-B-binding protein 1 QENEDS(0.152)S(0.825)DAT(0.017)T(0.006)PVPR 168.55 1.2626e-20 0.0 7244.1 10137.0 7040.2 7750.6 6003.8 5268.7 6309.4 7183.2 6651.7 3927.7 True False 7140.797805594763 10113.528399315424 6461.381931957896 8320.604979243657 5650.668287924953 5043.369982939572 6636.0698598686995 7516.957695560847 5902.515500493746 4606.597711668724 1.5501240291738074 2.195444237229006 1.4026364654310748 1.806236511203742 1.2266467882818486 1.0948145027217124 1.4405577120527 1.6317807992045947 1.28131776854367 1.0 12.169485899378316 -6.259532515529594 24.990403863021307 1.3096252797638777 1.7472431885867776 0.44181294095332 0.25151538606323487 173.16409260479793 2269399.6364584253 0.07570000613101963 0.09287522225578165 5.501327306557286e-07 6.259532515529594 0.43761790882289997 QENGAS(ph)VILR ddPTM_PC-9_AZD4547_30min_R2 1 QENGASVILR 10 0 P29692-2;P29692;E9PRY8;A0A087X1X7;E9PK01;E9PI39;E9PQ49;P29692-4;E9PL12;E9PPR1;H0YCK7;E9PK06;E9PIZ1;E9PMW7;E9PK72 P29692-2 EEF1D Elongation factor 1-delta 1 QENGAS(1)VILR 87.641 0.010498 3062700.0 8021.7 8099.8 10242.0 13191.0 12323.0 10143.0 8765.0 13680.0 10464.0 8668.0 True False 10572.433738274796 10717.901949778023 10106.18438799608 10150.01874891842 10612.164160463471 9508.75660656436 9545.068019945089 11566.070335126868 11017.10567732061 8364.535958333865 1.2639593865026224 1.2813504542471865 1.208218177115606 1.2134586783389485 1.2687092521719894 1.1367942769246475 1.1411353920279368 1.3827509849608821 1.3171209654904885 1.0 13.030069790355439 -5.259636082249934 23.91324703684352 1.2195504198233538 1.2726549245885603 0.05305619078627377 0.10004382244606098 317.32827697405133 4207872.024711764 0.025831560504592822 0.0616261903253704 5.500015554921497e-06 5.259636082249934 0.05310450476520656 QEPCAQHNGSEPAS(ph)PKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QEPCAQHNGSEPASPKR 17 1 M0QZ09;Q8N6T7-2;Q8N6T7 M0QZ09 SIRT6 NAD-dependent protein deacetylase sirtuin-6 1 QEPCAQHNGS(0.001)EPAS(0.999)PKR;QEPCAQHNGS(0.002)EPAS(0.998)PKR;QEPCAQHNGSEPAS(1)PKR;QEPCAQHNGSEPAS(1)PKR 94.176 0.00081325 21532400.0 12764.400000000001 17074.0 20522.7 25644.5 25959.5 21088.399999999998 25764.0 20140.8 23382.200000000004 19017.899999999998 True False 14925.160811608277 18768.993881865033 21012.039000773162 24207.721805590765 20872.922326829994 19982.487179993503 23323.447404793 19612.12534094156 23724.120440223563 22465.694724386423 0.6643534061471544 0.8354513008445434 0.9352944237226137 1.077541651953161 0.9291020190073409 0.889466692445642 1.038180554437762 0.8729810309250162 1.0560154373713235 1.0 14.455436055696572 -4.901965805900138 1.8961832877417195 0.9728651954675697 0.6128444068579432 0.6927814126720722 0.06527296687452701 0.34096989593468 1.592528986360348 0.017423001075544946 0.2018856543236822 1.2532398446763576e-05 4.901965805900138 -0.3600207886096265 QEPCAQHNGSEPAS(ph)PKR ddPTM_PC-9_Lapatinib_30min_R1 1 QEPCAQHNGSEPASPKR 17 1 M0QZ09;Q8N6T7-2;Q8N6T7 M0QZ09 SIRT6 NAD-dependent protein deacetylase sirtuin-6 1 QEPCAQHNGSEPAS(1)PKR 98.727 0.00060856 8451900.0 2438.3 2392.6 2340.6 2665.5 2714.7 3217.3 2218.4 4231.7 2795.6 2140.5 True False 2403.5293948705425 2387.060081700905 2148.16490297728 2861.529761847337 2555.0266833055516 3079.70357889261 2333.257897285436 4428.320230580362 2480.7300890269134 2510.482572963031 0.9573973628638833 0.9508371447819074 0.8556780780365582 1.1398325535755374 1.017743246187902 1.2267376846427371 0.9294061318782932 1.7639318744020505 0.9881486992753741 1.0 11.293748994934912 -6.456312692949566 0.9654287184861923 1.2341532003924451 0.9289407400324489 0.15450703065677918 0.22825493039956066 0.8572265043068428 1.7255540727478234 0.11243089876299861 0.14255205526023926 3.4969329644924615e-07 6.456312692949566 -0.3052124603599963 QEPES(ph)EEEEEEKQEK ddPTM_PC-9_AZD4547_30min_R2 1 QEPESEEEEEEKQEK 15 1 P49756 P49756 RBM25 RNA-binding protein 25 1 QEPES(1)EEEEEEKQEK 71.513 0.010156 12662000.0 64316.0 54172.0 39268.0 37966.0 41544.0 63302.0 60444.0 49177.0 61614.0 49686.0 True False 84767.15014409425 71682.03960880208 38747.280662744575 29213.525268852758 35776.33270163875 59343.71593303135 65823.39890445645 41577.824625039015 64870.79025252601 47946.50826324139 1.767952520727807 1.4950419166135136 0.8081356091669873 0.6092941139417563 0.7461718068230422 1.2377067294914514 1.3728507307156825 0.8671710648200636 1.3529825758398295 1.0 15.549138133380314 QEPES(ph)EEEEEEKQEK ddPTM_PC-9_Lapatinib_30min_R1 3 QEPESEEEEEEKQEK 15 1 P49756 P49756 RBM25 RNA-binding protein 25 1 QEPES(1)EEEEEEKQEK;QEPES(1)EEEEEEKQEK;QEPES(1)EEEEEEKQEK 88.385 0.0022955 111830000.0 131859.0 146894.0 101065.0 109183.0 127977.0 106482.0 117453.0 118178.0 107053.0 120455.0 True False 129978.6664800208 146553.87596814058 92755.82582218207 117212.68204381084 120449.64447246281 101928.01308166567 123534.14163805719 123668.98131000003 94995.5638219338 141275.4862538018 0.9200369429025625 1.0373623892885149 0.6565599473892164 0.8296745964352085 0.8525870104320483 0.7214840718973122 0.8744202190614143 0.8753746639939244 0.6724136390603109 1.0 17.108151629222668 -5.240618708938193 24.977503698932853 0.807181526302845 0.9786996788681075 0.30336912002656546 0.10197737858607343 914.4605937861237 1097028.329958565 0.024278892774935376 0.06408765360595495 5.7462073202267385e-06 5.240618708938193 0.17151815256526248 QEPES(ph)EEEEEEKQEKEEK ddPTM_PC-9_Lapatinib_30min_R1 1 QEPESEEEEEEKQEKEEK 18 2 P49756 P49756 RBM25 RNA-binding protein 25 1 QEPES(1)EEEEEEKQEKEEK 44.733999999999995 0.034642 6795200.0 24374.0 27208.0 22153.0 29330.0 26816.0 24268.0 23884.0 29706.0 20974.0 22058.0 True False 24026.42229035582 27145.00154765453 20331.665853052924 31487.026042011767 25238.735602284472 23230.114211471042 25120.596654690475 31086.249207084675 18611.68725398857 25870.695909562502 0.9287118666751832 1.0492567205206493 0.7858955910628518 1.2170923485043676 0.9755723499094417 0.8979315551726063 0.9710058338788339 1.201600811812502 0.7194119291978223 1.0 14.6590312419127 -5.6800827221443235 24.12902420783269 0.9999332538092192 0.9340924692564511 0.051787909152965717 0.14615467920198177 85.43788994880983 25330.283377128482 0.03807008250459634 0.06593929755880328 2.0888982105388185e-06 5.6800827221443235 -0.0658407845527681 QEPGGS(ph)HGSETEDTGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QEPGGSHGSETEDTGR 16 0 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 QEPGGS(0.798)HGS(0.198)ETEDT(0.004)GR 157.47 4.5506e-05 13277000.0 3473.6 3389.5 3460.4 3982.6 2905.3 2904.9 3526.2 3792.6 3667.5 2833.3 True False 4061.6118732727386 3725.9871595748814 3542.9090596400783 3759.4678337634114 2336.0273208705544 2752.5619302158148 3192.1728085227855 3693.048268591862 3721.1302492716677 3346.954861609542 1.2135245443135494 1.1132469105911584 1.0585470094856022 1.1232502346791413 0.697956027930166 0.822407843556072 0.9537543649416526 1.1034054599756042 1.111795767536042 1.0 11.708633379047393 -6.106831591710903 23.87361974189473 0.944031244773407 1.121319157643699 0.3462111979035377 0.12026246983495656 27.268003566971622 6074.7671877194025 0.03968938414082914 0.05123882047206031 7.819309586276835e-07 6.106831591710903 0.17728791287029189 QEPGGSHGS(ph)ETEDTGR ddPTM_PC-9_AZD4547_30min_R2 1 QEPGGSHGSETEDTGR 16 0 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 QEPGGS(0.449)HGS(0.487)ET(0.033)EDT(0.031)GR 139.81 1.9367e-05 12786000.0 2406.7 1103.2 2138.8 1244.6 2076.2 2153.7 2936.1 4246.2 2892.8 1075.2 True False 3171.980537530193 1459.7878257481805 2110.4381145329057 957.676698878316 1787.955467820682 2019.0287985366906 3197.407212020624 3590.0473579689833 3045.707502231753 1037.5575752654097 3.0571609837832785 1.4069463329538732 2.034044341098903 0.9230106566696696 1.7232349417942603 1.9459438653514898 3.0816672618892684 3.4600945947993687 2.9354587878678964 1.0 10.018975680153163 -7.16554328728943 5.0818939258980835 2.820917713495485 1.7749601976239233 0.16365444490915104 0.7994136700501439 0.2995699928613607 12.292830959320465 0.30094173390893564 0.23073324473460297 6.830566325097006e-08 7.16554328728943 -1.0459575158715617 QEPGGSHGS(ph)ETEDTGR ddPTM_PC-9_Lapatinib_30min_R1 2 QEPGGSHGSETEDTGR 16 0 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 QEPGGS(0.255)HGS(0.371)ET(0.371)EDT(0.004)GR;QEPGGS(0.064)HGS(0.577)ET(0.352)EDT(0.007)GR 162.82 6.374399999999999e-05 26019000.0 5251.0 6690.8 7454.1 6616.6 7381.1 7272.4 7465.1 7830.2 6934.8 5388.1 True False 5176.1197770845365 6675.307863681524 6841.252671658101 7103.206836330558 6946.958209800938 6961.376404792405 7851.606350985172 8194.019677550476 6153.7297973185805 6319.425905808044 0.8190806972398046 1.0563155519469571 1.0825750271667014 1.1240272363668602 1.099302106448648 1.1015836736679447 1.242455638853038 1.2966398846483085 0.9737798795398208 1.0 12.625577786029046 -4.136498847967093 1.0993491592068039 1.1360561518725918 7.249200385136642e-11 0.4705349511484008 0.0927364087368997 5.042741355264972 1.8444405787424254 0.02846902895366168 9.386412772111933 7.302997501032012e-05 4.136498847967093 -1.1360561518000998 QEPGGSHGSET(ph)EDTGR ddPTM_PC-9_AZD4547_30min_R2 1 QEPGGSHGSETEDTGR 16 0 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 QEPGGS(0.022)HGS(0.078)ET(0.617)EDT(0.283)GR 178.57 1.6614e-05 13434000.0 3922.4 5582.3 4563.1 5933.8 6325.2 5857.8 4755.2 7280.7 4753.6 5119.5 True False 5169.641609011685 7386.669307173738 4502.590312523426 4565.8540862961245 5447.05516089942 5491.510839981533 5178.403587956975 6155.63510884197 5004.865591333258 4940.267863254527 1.0464294147819857 1.4951961131734226 0.9114061093758651 0.9242118469439129 1.1025829594007144 1.1115815967848879 1.0482029985608048 1.2460124186033081 1.0130757541628879 1.0 12.270373552081788 -5.275263112338827 24.995393128981295 1.0537076082175152 1.2708128010011026 0.3050134651813291 0.1360146280464019 845.8189654486166 1529367.9392288516 0.0349741674781234 0.07343155285042155 5.305629113778541e-06 5.275263112338827 0.21710519278358742 QEPGGSHGSET(ph)EDTGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QEPGGSHGSETEDTGR 16 0 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 QEPGGS(0.006)HGS(0.065)ET(0.464)EDT(0.464)GR 147.49 7.3662e-05 11713000.0 960.83 1080.8 2937.7 2230.9 2061.1 2704.3 3016.5 2190.9 951.07 821.82 True False 1123.4795417424702 1188.0946812416382 3007.745909289292 2105.9099056753857 1657.242250730148 2562.48174735193 2730.755282431225 2133.391196450434 964.9775995023322 970.8094604764594 1.1572606031167871 1.2238186066486603 3.0981835589170434 2.169230926779221 1.7070726215593297 2.6395310837765225 2.8128643092239844 2.19753853181797 0.9939927851843707 1.0 9.923044357303707 -5.056457461690329 22.518606093822555 2.1567842441405674 1.173898802923803 0.2139349406801443 0.666654723466562 113.33660770421439 45205.30088506376 0.16721705289684471 0.4424258728121091 8.780970908066173e-06 5.056457461690329 -0.9828854412167642 QEPIES(ph)DEEEAEPPREVEPGQR ddPTM_PC-9_AZD4547_30min_R2 2 QEPIESDEEEAEPPREVEPGQR 22 1 P56524-2;P56524 P56524-2 HDAC4 Histone deacetylase 4 1 QEPIES(1)DEEEAEPPREVEPGQR;QEPIES(1)DEEEAEPPREVEPGQR 100.81 4.1933999999999995e-05 123212000.0 51217.0 46094.0 77036.0 93700.0 92936.0 63142.0 63523.0 89394.0 67861.0 65417.0 True False 67502.94062022018 60992.984082701856 76014.45230557174 72098.91265056907 80033.44059213136 59193.720758324605 69176.42393964311 75580.21136976095 71447.99391902273 63126.77074138515 1.069323518808892 0.9661983872511887 1.2041555652669809 1.1421289542267348 1.267820920541123 0.9376960054051666 1.0958334020132583 1.197276693898924 1.131817659606375 1.0 15.945964331275267 -5.25333924459055 24.918118294372672 1.1275336997721637 1.0177609543663089 0.1613763488862141 0.09448406339499614 989.173643023843 3042932.87985927 0.02406127785942599 0.06136241719095236 5.580341219264716e-06 5.25333924459055 -0.1097727454058548 QEPIES(ph)DEEEAEPPREVEPGQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QEPIESDEEEAEPPREVEPGQR 22 1 P56524-2;P56524 P56524-2 HDAC4 Histone deacetylase 4 1 QEPIES(1)DEEEAEPPREVEPGQR 68.587 0.0010555999999999999 59260000.0 10316.0 9030.7 11111.0 11416.0 15066.0 11762.0 11165.0 10604.0 11499.0 8293.3 True False 12062.29504971256 9927.208214182892 11375.928378702147 10776.398531171364 12113.925452185926 11145.18001418238 10107.370372400015 10325.656235866722 11667.15112102928 9796.809640273319 1.2312472623869455 1.0133103100598713 1.161187039088449 1.0999906017231458 1.236517386475212 1.1376336198639707 1.0317001905242726 1.053981511840282 1.1909133227481778 1.0 13.258096292510444 -10.561853661859155 4.449052571583955 0.999993445971624 1.1236401292332772 0.20591407462527356 0.07515922136681523 52368006.66095142 0.050994207661618905 3516.06873969128 0.017919321026166578 2.7424981175096736e-11 10.561853661859155 0.12364668326165318 QEPIES(ph)DEEEAEPPREVEPGQR ddPTM_PC-9_Lapatinib_30min_R1 1 QEPIESDEEEAEPPREVEPGQR 22 1 P56524-2;P56524 P56524-2 HDAC4 Histone deacetylase 4 1 QEPIES(1)DEEEAEPPREVEPGQR 61.108999999999995 0.0031436999999999997 74630000.0 7976.9 11384.0 12044.0 7852.3 11423.0 9194.9 7861.9 8362.2 12946.0 7690.5 True False 7863.147943215697 11357.641047430876 11053.788811184462 8429.784336504918 10751.121598482083 8801.655561358793 8268.950713427857 8750.738339711957 11487.885152576331 9019.792678052889 0.8717659289828734 1.2591909207698841 1.2255036457856427 0.9345873721705833 1.1919477511541803 0.9758157283121518 0.9167561837145113 0.9701706737677465 1.2736307321706901 1.0 13.138878557856446 -6.782108570791656 24.97955326023335 1.0185029339353626 1.1037927559031744 0.051566677204591405 0.14461795642805533 700.8763639003438 847030.9327915852 0.05083884410628971 0.04488215350271832 1.6515488701564892e-07 6.782108570791656 0.08528982196781176 QEPLEEDS(ph)PSSSSAGLDK ddPTM_PC-9_AZD4547_30min_R2 2 QEPLEEDSPSSSSAGLDK 18 0 P15408;P15408-3;P15408-2;C9JCN8 P15408 FOSL2 Fos-related antigen 2 1 QEPLEEDS(0.657)PS(0.109)S(0.196)S(0.033)S(0.006)AGLDK;QEPLEEDS(0.918)PS(0.079)S(0.002)SSAGLDK 283.64 1.2589e-105 22317000.0 74889.0 77723.0 91375.0 109210.0 97650.0 101073.0 85731.0 100345.0 93984.0 98820.0 True False 98702.14421203225 102845.4397938958 90163.30779663559 84033.32177768025 84092.98306169422 94752.88933207934 93360.89291704648 84838.9859487067 98951.80236786121 95360.341878467 1.035043942458011 1.0784927755918519 0.9455010963734293 0.8812187553267941 0.8818443957433312 0.9936299248259635 0.9790326993167795 0.8896673845489212 1.0376619925919663 1.0 16.541101787596638 -5.268791614131766 24.09030110084264 0.9446807758258223 1.0567683622794304 0.39191473913900876 0.05218111149129114 289.3283801065765 948016.8374147663 0.013698267908978148 0.029489385663325696 5.3852812043095574e-06 5.268791614131766 0.11208758645360806 QEPLEEDS(ph)PSSSSAGLDK ddPTM_PC-9_Lapatinib_30min_R1 2 QEPLEEDSPSSSSAGLDK 18 0 P15408;P15408-3;P15408-2;C9JCN8 P15408 FOSL2 Fos-related antigen 2 1 QEPLEEDS(0.86)PS(0.12)S(0.017)S(0.003)SAGLDK;QEPLEEDS(0.875)PS(0.116)S(0.008)SSAGLDK 190.37 4.7841e-11 21030000.0 107119.0 116611.0 117338.0 103472.0 133507.0 120390.0 117730.0 110152.0 125928.0 111243.0 True False 105591.46341678142 116340.99439405854 107690.92257777856 111081.67605247312 125654.38074486087 115241.20034279699 123825.48334268594 115270.0640496465 111744.6625593721 130471.20432801962 0.8093085670560097 0.8916986318418881 0.8253999273819163 0.8513884471641804 0.9630813281139898 0.8832692312172374 0.9490636955521191 0.8834904578625971 0.8564699247999057 1.0 16.993371906080654 -6.146365849839058 7.912576245051501 0.9160089429485508 0.8457836927199849 0.4198787450321374 0.04460866123680058 0.3091697046440318 19.354595520835936 0.012648924960489725 0.01637119678742658 7.138946875406993e-07 6.146365849839058 -0.07022525022856596 QEPLGS(ph)DSEGVNCLAYDEAIMAQQDR ddPTM_PC-9_AZD4547_30min_R2 2 QEPLGSDSEGVNCLAYDEAIMAQQDR 26 0 F5H3F0;J3KR44;F5H6Q1;F5GYJ8;Q96FW1 F5H3F0 OTUB1 Ubiquitin thioesterase OTUB1 1 QEPLGS(0.95)DS(0.05)EGVNCLAYDEAIMAQQDR;QEPLGS(0.936)DS(0.064)EGVNCLAYDEAIMAQQDR 165.1 3.4092e-13 14370500.0 23624.0 24581.0 32361.0 37589.0 34925.0 31337.0 27161.0 41173.0 29631.0 29403.0 True False 31135.940590274353 32526.327542345953 31931.871995698228 28923.436794260837 30076.26659938218 29377.49243615372 29578.276382170974 34810.65891141654 31197.23416711457 28373.609919576662 1.0973556300564982 1.1463584519044254 1.1254074503105969 1.0193781079052904 1.060008461546895 1.0353808528214248 1.0424572856964225 1.2268674662859367 1.0995158619414769 1.0 14.79226209314214 -12.0490027847963 1.947111421730744 2.4458357947662384e-05 1.0945307955864263 0.19092778224666374 0.05851101435292325 2252967.4836753304 143568.3595725453 9942124.46658968 0.01581801542452338 8.932997556710372e-13 12.0490027847963 1.0945063372284787 QEPLGS(ph)DSEGVNCLAYDEAIMAQQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QEPLGSDSEGVNCLAYDEAIMAQQDR 26 0 F5H3F0;J3KR44;F5H6Q1;F5GYJ8;Q96FW1 F5H3F0 OTUB1 Ubiquitin thioesterase OTUB1 1 QEPLGS(0.914)DS(0.086)EGVNCLAYDEAIMAQQDR;QEPLGS(0.912)DS(0.088)EGVNCLAYDEAIMAQQDR;QEPLGS(0.947)DS(0.053)EGVNCLAYDEAIMAQQDR 141.36 7.8208e-10 15322200.0 27563.5 29077.9 35848.3 29745.5 33369.1 31118.1 32147.7 29125.9 29813.3 29331.8 True False 32229.456146059747 31964.561742853675 36703.05942743485 28078.956071212153 26830.664397088654 29486.212055715743 29102.43712680735 28361.37598644195 30249.2631112777 34649.423149598944 0.9301585197222192 0.9225135323276992 1.0592689889516869 0.8103729735984698 0.7743466400940419 0.8509870980653551 0.8399111581499503 0.818523756196219 0.8730091401717268 1.0 15.080543713841509 -5.7806601358236405 24.999939183271632 0.8410508575348181 0.9658337017809249 0.39103512025499976 0.06645584030408054 211.32427108260802 274863.262385253 0.01795870999869382 0.026682596344996472 1.6570662201921325e-06 5.7806601358236405 0.12478284424610675 QEPLGS(ph)DSEGVNCLAYDEAIMAQQDR ddPTM_PC-9_Lapatinib_30min_R1 2 QEPLGSDSEGVNCLAYDEAIMAQQDR 26 0 F5H3F0;J3KR44;F5H6Q1;F5GYJ8;Q96FW1 F5H3F0 OTUB1 Ubiquitin thioesterase OTUB1 1 QEPLGS(0.68)DS(0.32)EGVNCLAYDEAIMAQQDR;QEPLGS(0.865)DS(0.135)EGVNCLAYDEAIMAQQDR 142.27 1.3507e-10 8511700.0 25184.0 37201.0 41667.0 34518.0 40728.0 41516.0 35720.0 34451.0 40642.0 31747.0 True False 24824.87154182003 37114.863370122606 38241.300099271255 37056.56886867243 38332.45911432881 39740.457458522855 37569.40682069767 36051.7192295588 36064.46998076685 37234.426649781526 0.6667182437188325 0.9967889050425429 1.0270414651193678 0.995223297439706 1.029489710554029 1.0673041331430313 1.0089965174988968 0.9682361855240313 0.9685786307381871 1.0 15.184349522089978 -4.761554451772833 6.016318131167903 1.00960060099009 0.6541566200702682 0.9310086111324066 0.02779008232873901 0.0339413292129891 4.766165351684278 0.007652088814984909 0.049792482653775984 1.7315919104217558e-05 4.761554451772833 -0.35544398091982177 QEPLLIGSTK ddPTM_PC-9_Lapatinib_30min_R1 1 QEPLLIGSTK 10 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 108.31 0.009341799999999999 0.0 16161.0 20356.0 17319.0 17924.0 23403.0 19673.0 19923.0 14931.0 21086.0 21194.0 False True 15930.541176435572 20308.866932668905 15895.098673273305 19242.19075271118 22026.481552068293 18831.631650002873 20954.515456012323 15624.748768295342 18711.072634576296 24857.354660770136 0.6408783796120165 0.8170164206861621 0.6394525439329609 0.7741045262181174 0.8861152706176927 0.7575879214421374 0.8429905652463787 0.6285764910034579 0.7527378874352266 1.0 14.601385151368074 -11.868889978113442 2.171052232674415 2.3993541397032536 0.7518889301982118 0.4430955189383955 0.08441314109408425 4147575.09692417 398316.8834654311 28594161.187558245 0.021916737147315443 1.352415133557679e-12 11.868889978113442 -1.6474652095050417 QEPQS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 2 QEPQSPSR 8 0 K7ENY9;Q8WUQ7;Q8WUQ7-2 K7ENY9 CACTIN Cactin 1 QEPQS(0.999)PS(0.001)R;QEPQS(0.731)PS(0.269)R 115.91 0.0036131 29644000.0 95239.0 87896.0 132418.0 162310.0 156726.0 134773.0 110667.0 147296.0 126118.0 123468.0 True False 125523.02090573702 116306.66310003826 130662.05079961588 124891.9371645024 134967.3001876811 126345.62300468264 120516.1486096134 124534.78772535408 132784.340005 119145.4229007343 1.0535278473124075 0.9761739919874124 1.0966602628829194 1.0482310954450662 1.1327946714338222 1.060432032793632 1.0115046442868487 1.0452335028355215 1.1144728582282926 1.0 16.862364004351498 -5.266466875573427 24.996859031795267 1.0652208260999394 1.0148509201757452 0.16772941463765378 0.04338490279407003 661.2448292432123 3287749.9781337245 0.0111507684978072 0.02440396269139563 5.414185412804715e-06 5.266466875573427 -0.050369905924194214 QEPQS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QEPQSPSR 8 0 K7ENY9;Q8WUQ7;Q8WUQ7-2 K7ENY9 CACTIN Cactin 1 QEPQS(1)PSR 126.03 0.0034878 11862000.0 46596.0 45547.0 51516.0 55187.0 60404.0 54941.0 41733.0 47050.0 43150.0 46132.0 True False 54483.78248704985 50068.605150363524 52744.33681551799 52095.05130866806 48568.26981374216 52059.79724189711 37779.748119244956 45814.98735359573 43780.987118220124 54495.3664192889 0.9997874327121701 0.9187681162676153 0.9678682846116047 0.9559537761035911 0.8912366868048287 0.955306857492205 0.693265328809178 0.8407134471047303 0.8033891685646807 1.0 15.733845946538064 -7.198428477916127 24.99912765694187 0.8210674303735721 0.94548148222743 0.34993409127923103 0.07507420958060504 212.25010812664564 84208.60225550536 0.026886893188928083 0.020826493186256942 6.332446394507345e-08 7.198428477916127 0.1244140518538579 QEPQS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 2 QEPQSPSR 8 0 K7ENY9;Q8WUQ7;Q8WUQ7-2 K7ENY9 CACTIN Cactin 1 QEPQS(0.998)PS(0.002)R;QEPQS(0.996)PS(0.004)R 101.3 0.0046297 27921000.0 107890.0 103138.0 111122.0 106536.0 111140.0 109331.0 94103.0 99411.0 122165.0 85028.0 True False 106351.46881539738 102899.19029777973 101985.97810332455 114371.0128336776 104602.96370964698 104655.16799300886 98975.19289048467 104029.99797769818 108405.4912455189 99724.97650731182 1.0664476697831031 1.0318296769940596 1.0226723703048148 1.1468642745209565 1.0489143981094597 1.0494378806430258 0.9924814861523464 1.0431689394288373 1.0870445403170452 1.0 16.60566725799938 -6.517806983284018 24.137084240857543 1.036133387721509 1.0658576610663764 0.1299268166644466 0.03951563838416041 350.3492914065658 1667361.6003955586 0.013296977162994215 0.013705724006963835 3.0352398586217383e-07 6.517806983284018 0.02972427334486727 QEPQSPS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QEPQSPSR 8 0 K7ENY9;Q8WUQ7;Q8WUQ7-2 K7ENY9 CACTIN Cactin 1 QEPQS(0.036)PS(0.964)R 96.756 0.0060224 13015000.0 51257.0 60765.0 66373.0 59890.0 79130.0 79173.0 68765.0 54642.0 46706.0 55396.0 True False 59933.79772810361 66797.34761810528 67955.58404100433 56534.557465999795 63625.04453945793 75021.02850389907 62251.08138451295 53207.70539798465 47388.986890929074 65438.856285505244 0.9158747742566978 1.0207597047031665 1.0384592258843703 0.8639294858599514 0.9722823434117831 1.146429396268594 0.9512862069733578 0.8130903933565569 0.724171991701294 1.0 15.99785991319511 -7.672731439431624 4.840707514643821 0.826868578633984 0.9935925095949791 0.3163313328095946 0.095155638684335 0.22069735678073785 8.856186316706847 0.047135639103765975 0.026007548771668717 2.124557847518313e-08 7.672731439431624 0.16672393096099514 QEPS(ph)PKPNNK ddPTM_PC-9_AZD4547_30min_R2 1 QEPSPKPNNK 10 1 Q8N684-2;Q8N684;Q8N684-3;F5H669;F5H6M0;F5H047;F5H5B7;F5H1W4;F5H2K8;F5H6P5;F5H6A8;F5GXA3;C9JM38;C9J286;C9J323;J3QT54 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 1 QEPS(1)PKPNNK 99.73200000000001 0.020561000000000003 9662900.0 23210.0 19483.0 17744.0 19420.0 20151.0 22976.0 27777.0 20991.0 23629.0 24923.0 True False 30590.297202009304 25780.498739169518 17508.702966276353 14943.019036009087 17353.38148157912 21539.307087885507 30249.09918882084 17747.323275193576 24877.98070044042 24050.453355970796 1.2719218531660201 1.0719340029725144 0.7279988741638261 0.6213196406253737 0.7215407221116248 0.8955884019765528 1.2577350930189912 0.7379205295016862 1.034407972782109 1.0 14.553776468898041 -4.9968497493446735 3.9811249578449064 0.8655488070210574 1.249752204399128 0.3326812203368825 0.17854848985731597 0.2453638291476336 8.892766774966516 0.04878971280663249 0.20031767260256758 1.0072800921528698e-05 4.9968497493446735 0.38420339737807063 QEPS(ph)PKPNNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QEPSPKPNNK 10 1 Q8N684-2;Q8N684;Q8N684-3;F5H669;F5H6M0;F5H047;F5H5B7;F5H1W4;F5H2K8;F5H6P5;F5H6A8;F5GXA3;C9JM38;C9J286;C9J323;J3QT54 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 1 QEPS(1)PKPNNK 58.674 0.035804 71422000.0 107820.0 116410.0 89069.0 115640.0 121730.0 91901.0 117540.0 106400.0 95309.0 74093.0 True False 126071.79645793 127966.41547311147 91192.74275606357 109161.06570993828 97877.88034611668 87081.5497775357 106405.76028409316 103607.11274011858 96702.71381808669 87525.47438013465 1.4404011786372457 1.4620476653155456 1.041899440156148 1.2471919344971203 1.11827877585696 0.9949280525956259 1.2157118945960688 1.1837366603708912 1.1048522102044724 1.0 16.417415355500722 -5.253666777001213 24.85751975733807 1.1242730069819094 1.451224474826965 0.7317631739673369 0.08161663971455013 269.21913039638895 860982.8267882077 0.020537437799375138 0.052197907538697394 5.576134272951176e-06 5.253666777001213 0.3269514678450556 QEPS(ph)PKPNNK ddPTM_PC-9_Lapatinib_30min_R1 2 QEPSPKPNNK 10 1 Q8N684-2;Q8N684;Q8N684-3;F5H669;F5H6M0;F5H047;F5H5B7;F5H1W4;F5H2K8;F5H6P5;F5H6A8;F5GXA3;C9JM38;C9J286;C9J323;J3QT54 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 1 QEPS(1)PKPNNK;QEPS(1)PKPNNK 94.12200000000001 0.031007 28659000.0 83998.3 105668.0 104275.0 104406.0 119530.0 98051.0 113300.0 106411.0 114637.0 95570.0 True False 82800.46883859846 105423.33223822257 95701.91201314029 112084.36552820611 112499.48040502184 93857.58729804469 119166.11961884232 111355.2435324542 101725.37387887324 112089.14716097942 0.7387019255279251 0.9405311299836764 0.8538017679418666 0.9999573408051142 1.0036607758595317 0.8373476797289655 1.0631369997641176 0.9934525005576926 0.9075399042226452 1.0 16.774287072874465 -3.9125189361125225 0.9128017733790971 0.968093150278031 4.725493053735147e-13 0.4836971508188669 0.06756863046040273 7.821050774439415 1.5933417886857302 0.02213193085877775 10.983079319075777 0.0001223153785923113 3.9125189361125225 -0.9680931502775585 QEPVS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 QEPVSPK 7 0 E7EWM1;Q15596 E7EWM1 NCOA2 Nuclear receptor coactivator 2 1 QEPVS(1)PK;QEPVS(1)PK 83.883 0.020366 26309000.0 182069.0 186559.0 165075.0 186985.0 202943.0 199969.0 201046.0 194846.0 186284.0 191965.0 True False 239963.15472954008 246860.54838991544 162885.9976419112 143878.4971394522 174767.86750117142 187464.90681830546 218938.70452229134 164737.02781565263 196130.59193367645 185244.36377959864 1.295387075933091 1.3326211030292232 0.8793033931964098 0.7766956802563612 0.9434449930639076 1.0119871017579178 1.1818913140201222 0.8892957629288771 1.058766852237567 1.0 17.49907012238804 -5.254641508016909 24.98886267035514 0.9652667892916242 1.3140041364470016 0.6378238368509184 0.10437786650993844 344.8380347339131 1267610.3818874506 0.028942758294795853 0.07299082905355998 5.563633224950059e-06 5.254641508016909 0.3487373471553774 QEPVS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QEPVSPK 7 0 E7EWM1;Q15596 E7EWM1 NCOA2 Nuclear receptor coactivator 2 1 QEPVS(1)PK;QEPVS(1)PK 89.679 0.016438 21418000.0 246900.0 243020.0 188906.0 261300.0 259200.0 184200.0 256330.0 214618.0 185866.0 187712.0 True False 288695.29350271774 267145.41953677125 193410.23546999446 246660.2081460304 208411.62068276823 174540.2277344324 232048.56673150908 208984.50490656763 188583.93862607458 221742.69967262584 1.3019382100467736 1.204754068256482 0.8722281985180997 1.1123712686378944 0.9398804154114693 0.7871295334282404 1.0464766915623311 0.9424639693442264 0.850462896431288 1.0 17.758527082595755 -5.132714170688116 4.153404324337903 0.9460700502487693 1.2825078120977573 0.6553805164507678 0.09065412918541693 0.13235804409192312 3.7347136657599354 0.023434339296298103 0.07148009705121626 7.366917889627802e-06 5.132714170688116 0.336437761848988 QEQALLEEIER ddPTM_PC-9_Lapatinib_30min_R1 2 QEQALLEEIER 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 117.09 0.0055124 2825100.0 11310.599999999999 12178.7 12393.0 10661.8 10590.2 9139.3 12296.6 8534.9 11376.5 13107.599999999999 False True 11149.308769889984 12150.500968407097 11374.095378363434 11445.904338722166 9967.305257134285 8748.43344374886 12933.257780274116 8931.462612184312 10095.158770144033 15373.231195220847 0.7252417288407154 0.7903674129472784 0.7398636782291647 0.7445347170919027 0.6483546061697733 0.5690692693458307 0.8412842827924647 0.5809749751867961 0.6566712385931179 1.0 13.908132806737457 -10.573728401692682 5.5564281286093316 1.0000015961917526 0.7001039608632894 0.5435841835883399 0.08257869662907975 1.6612321292075562e-06 2.838191617405121e-07 0.08134627958555075 0.019729265817660234 2.668526981439478e-11 10.573728401692682 -0.29989763532846314 QEQDEDGTEEDNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QEQDEDGTEEDNSR 14 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q8TEW0-6;Q8TEW0-7;Q8TEW0-8;Q5VWU8;Q8TEW0-9;Q8TEW0-10 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 0 151.66 0.0011319000000000001 487010.0 0.0 0.0 386.52 501.59 0.0 0.0 0.0 677.14 478.84 0.0 False True 0.0 0.0 395.73610268526306 473.4875384767208 0.0 0.0 0.0 659.365792489135 485.84212912372016 0.0 0.0 QEQDEDGTEEDNSR ddPTM_PC-9_Lapatinib_30min_R1 2 QEQDEDGTEEDNSR 14 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q8TEW0-6;Q8TEW0-7;Q8TEW0-8;Q5VWU8;Q8TEW0-9;Q8TEW0-10 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 0 ; 225.72 9.0069e-20 1562850.0 1675.8000000000002 3094.4900000000002 1963.3400000000001 1951.54 4321.299999999999 2204.42 1953.22 2122.4 1769.6 1937.18 False True 1651.902784695917 3087.3248985298997 1801.921763911567 2095.0627617465957 4067.1296300026775 2110.142095354006 2054.34817442114 2221.014452202133 1570.2890132858859 2272.018981869903 0.7270638132329238 1.3588464370966604 0.793092741869859 0.9221149904400578 1.7900949166610278 0.9287519656272104 0.9041949872841215 0.9775510107640946 0.6911425590262966 1.0 11.149759172733194 -6.96916588403137 24.999653780841015 0.894939003676591 1.128326814521329 0.12093813348542282 0.29435942899061046 435.41638007218666 353025.3054773204 0.10406742365626734 0.09177793008610902 1.0735792674271857e-07 6.96916588403137 0.23338781084473803 QEQINTEPLEDTVLS(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 1 QEQINTEPLEDTVLSPTK 18 0 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 QEQINTEPLEDT(0.006)VLS(0.862)PT(0.132)K 161.31 4.1552e-06 60194000.0 35226.0 26663.0 42003.0 40530.0 37186.0 35661.0 37918.0 33674.0 40370.0 40129.0 True False 46427.13525368285 35281.2933266169 41446.01277572735 31186.434682257885 32023.36577708307 33431.11203260295 41292.62854310074 28470.45705153963 42503.87578301157 38724.09592431697 1.1989210889369974 0.9110940484077732 1.0702900038448966 0.8053495875851868 0.8269622572898817 0.8633154947746561 1.0663290532025267 0.7352129564801919 1.0976079561955912 1.0 15.240943936944412 -2.320813712859927 1.2951668244667882 0.9144059209558547 199.9554558540214 0.29612875317036735 0.12009636869881565 1186.3939842240468 3.747049307053884 0.03298612142014622 699643.4892960079 0.004777341499523336 2.320813712859927 199.04104993306555 QEQINTEPLEDTVLS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QEQINTEPLEDTVLSPTK 18 0 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 QEQINTEPLEDTVLS(0.773)PT(0.227)K;QEQINTEPLEDT(0.061)VLS(0.932)PT(0.008)K;QEQINTEPLEDT(0.002)VLS(0.994)PT(0.004)K 181.32 3.1508000000000003e-09 92250100.0 165440.0 167599.0 155110.0 205546.0 216816.0 186275.0 216261.0 246390.0 202719.0 163811.0 True False 193445.7244110551 184237.121096796 158808.41065795065 194029.9240091227 174332.4612266787 176506.4110816038 195775.19248594748 239922.5235717846 205683.38186833117 193508.63757283738 0.9996748818937935 0.9520873249259918 0.8206786665953066 1.0026938665003473 0.9009027370215414 0.9121371185054523 1.0117129392338209 1.2398543371557607 1.062915766697552 1.0 17.562038439283896 -7.533766812425695 10.334013404607617 1.1161170061768664 0.9318225018720683 0.5086932112957114 0.0744037499080382 0.17987330146816408 155.95509270826412 0.03313657427955398 0.01950901305266405 2.925722876945583e-08 7.533766812425695 -0.1842945043047981 QEQINTEPLEDTVLS(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 5 QEQINTEPLEDTVLSPTK 18 0 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 QEQINTEPLEDT(0.209)VLS(0.785)PT(0.006)K;QEQINTEPLEDTVLS(0.999)PT(0.001)K;QEQINTEPLEDT(0.003)VLS(0.99)PT(0.007)K;QEQINTEPLEDT(0.002)VLS(0.979)PT(0.019)K;QEQINTEPLEDT(0.064)VLS(0.858)PT(0.078)K 262.17 1.8062999999999996e-66 116994000.0 243027.6 227725.7 223065.6 236118.4 238764.90000000002 230902.1 210965.7 218938.0 231806.8 207330.5 True False 239561.98185819612 227198.41513307558 204726.00742611688 253483.33480389218 224721.21801185448 221026.9554420848 221888.47168290222 229110.65875246472 205698.2771501803 243167.30067447462 0.9851735047998706 0.9343296343829699 0.8419142165014256 1.0424236075360622 0.9241424212406185 0.9089501541902263 0.9124930493016488 0.9421935355493074 0.8459125736874725 1.0 17.89158971338889 -6.501048897800964 24.950133009926287 0.917579267127293 0.9471457907634094 0.05041069507533125 0.05864929075237196 2553.3698163652957 2918344.819133646 0.01791204701308454 0.02012953035437429 3.154649417149408e-07 6.501048897800964 0.02956652363611645 QEQINTEPLEDTVLS(ph)PTKK ddPTM_PC-9_AZD4547_30min_R2 1 QEQINTEPLEDTVLSPTKK 19 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 QEQINTEPLEDTVLS(0.94)PT(0.06)KK 119.69 2.2296999999999997e-05 24255000.0 31604.0 31102.0 29445.0 40698.0 29354.0 25651.0 34169.0 34858.0 29220.0 35480.0 True False 41653.414595963026 41155.11326724069 29054.540060978765 31315.704877832024 25278.703786922415 24047.03891501353 37209.974805876074 29471.497057152927 30764.509546187714 34237.855999271495 1.2165894557430617 1.2020353513992341 0.8486086296290568 0.9146514571034574 0.7383261319710057 0.7023523586151306 1.0868079708807648 0.8607868745572157 0.8985524545357721 1.0 15.06330474145019 -5.257922039472663 23.585417921672544 0.8733279348550375 1.2093125057961662 0.6045657486464314 0.10596972244452148 87.66161069193662 587795.6448681235 0.027943740199742773 0.06789269465343756 5.52176552010519e-06 5.257922039472663 0.33598457094112877 QEQINTEPLEDTVLS(ph)PTKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QEQINTEPLEDTVLSPTKK 19 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 QEQINTEPLEDTVLS(0.921)PT(0.079)KK;QEQINT(0.162)EPLEDT(0.097)VLS(0.543)PT(0.198)KK 69.71 0.0034576 22288500.0 51270.7 53139.3 49887.2 65739.0 61401.0 56731.0 73348.0 67096.0 59171.6 41216.2 True False 59949.81686751622 58414.61851860083 51076.70004625954 62055.85695871362 49369.914820766506 53755.926490782214 66399.9464464662 65334.80109408847 60036.8727083308 48688.37079274034 1.2312964244113713 1.1997653149509517 1.0490533820424182 1.2745519299234067 1.0139980865436513 1.1040814390691724 1.363774251743226 1.3418974599131626 1.2330844456451309 1.0 15.571289605591714 -7.241687948257672 24.828967478515857 1.2631805091116353 1.1434367456596666 0.10048200422598219 0.1190714378444493 1244.3804802141653 1564277.6068355942 0.04415613896090503 0.03414990802728129 5.732077475460447e-08 7.241687948257672 -0.11974376345196869 QEQINTEPLEDTVLS(ph)PTKK ddPTM_PC-9_Lapatinib_30min_R1 2 QEQINTEPLEDTVLSPTKK 19 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 QEQINTEPLEDTVLS(0.983)PT(0.017)KK;QEQINTEPLEDT(0.021)VLS(0.965)PT(0.014)KK 116.2 3.1714e-05 38599000.0 116382.0 112130.0 103570.0 110065.0 130516.0 115613.0 93217.0 99626.0 105159.0 97775.0 True False 114722.371338155 111870.36987424655 95054.87439176146 118159.54726607638 122839.30548432883 110668.50149706632 98043.32014571593 104254.9876625941 93314.88604663794 114675.27847300195 1.000410662749462 0.975540424788105 0.8289046746386605 1.0303837831437639 1.0711925632101162 0.9650598016478421 0.854964744374249 0.9091321952807718 0.813731497225944 1.0 16.807194885245664 -7.16859312321751 6.149745580184428 0.8871954663062491 0.9790146094225615 0.23870121568168812 0.07338949404169025 0.3465940232148055 18.8880829992199 0.029139228901752183 0.02247243731885794 6.782766660186695e-08 7.16859312321751 0.09181914311631234 QEQINTEPLEDTVLSPT(ph)K ddPTM_PC-9_AZD4547_30min_R2 2 QEQINTEPLEDTVLSPTK 18 0 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 QEQINTEPLEDTVLS(0.1)PT(0.9)K;QEQINTEPLEDT(0.006)VLS(0.402)PT(0.592)K 258.81 4.565999999999999e-65 85932000.0 71608.0 54569.0 79211.0 82266.0 78951.0 80849.0 71546.0 84681.0 74503.0 86041.0 True False 94377.85446107194 72207.36209504402 78160.610384452 63300.84469703002 67990.01644345945 75793.49924914932 77913.45539703257 71595.49722579498 78441.076479111 83028.73077884228 1.1366891144278661 0.8696671792728909 0.9413682426706348 0.762396872784193 0.8188733683591962 0.9128587000930445 0.938391502148396 0.8622978642959004 0.9447461829574261 1.0 16.34132302419954 -4.759003777008624 24.987324733328805 0.8871245601364425 1.1366894431714205 0.5462980734388632 0.06590173986213405 49.22973509755774 504948.36721700314 0.016431499481774053 0.1080438776824824 1.7417917251655845e-05 4.759003777008624 0.24956488303497804 QEQLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 QEQLSPK 7 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 QEQLS(1)PK;QEQLS(1)PK;QEQLS(1)PK 80.706 0.025013 59595000.0 383003.0 393690.0 320265.0 364069.0 375643.0 382390.0 397650.0 412420.0 410250.0 380485.0 True False 504789.987042704 520942.59347244556 316018.0768425665 280138.5168599791 323491.4535201636 358479.0928506508 433040.079649877 348689.96546878724 431934.9774580257 367164.33596061997 1.374833930212778 1.418826782589034 0.8606992724817937 0.762978561430937 0.8810535823796882 0.9763450796841534 1.179417599252675 0.9496836465788601 1.1764077693655755 1.0 18.486066405651634 -5.254405050259644 24.96144753148852 0.9681869629300272 1.3968304158149116 0.6541384740834528 0.12313379421847373 339.3284442784802 1204105.7904854245 0.034486017936970904 0.08719167794678215 5.566663248340203e-06 5.254405050259644 0.4286434528848845 QEQLS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QEQLSPK 7 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 QEQLS(1)PK;QEQLS(1)PK 74.533 0.034042 38598000.0 227800.0 259010.0 217814.0 254390.0 251150.0 175979.0 245450.0 213095.0 184823.0 165516.0 True False 266362.0407449125 284722.80106254306 223007.51182419492 240137.35304350776 201938.96039536045 166750.35144667592 222199.1990958872 207501.48204281612 187525.68672423667 195522.74057606483 1.362307217872127 1.4562132272883954 1.1405707140108217 1.2281811943510805 1.0328157215901927 0.8528437712942373 1.136436602930309 1.0612652084942067 0.959099111293824 1.0 17.57697688661581 -5.629811019457894 1.1360681737484803 1.0097004610055864 1.4320499920101095 0.731548562975997 0.09074885795434803 0.31098215604434853 0.7366661055818006 0.03269248241301505 0.11086279217590136 2.3452491138779257e-06 5.629811019457894 0.4223495310045231 QEQLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 QEQLSPK 7 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 QEQLS(1)PK;QEQLS(1)PK 95.48299999999999 0.013112 50389000.0 325100.0 425700.0 326260.0 397500.0 407610.0 368790.0 398460.0 366820.0 364100.0 372030.0 True False 320464.01438396156 424714.3178049294 299436.16220002074 426733.4760211287 383635.181192093 353017.71139147866 419090.30912024627 383863.7963422465 323091.22385702515 436334.8898011862 0.7344450830644769 0.9733677680426801 0.6862530803724115 0.9779953104725768 0.8792218778720501 0.8090522203079598 0.9604785656980184 0.8797458221073087 0.7404661680945112 1.0 18.735076312191246 -12.015495303311983 2.2723882966844435 2.901978407940484 0.8555644847209517 0.16791428075854653 0.09988271888993515 8726875.226415796 575000.5557858374 87121731.37918153 0.024702701680179556 9.649497472211757e-13 12.015495303311983 -2.046413923219532 QEQPSIESTS(ph)PISR ddPTM_PC-9_AZD4547_30min_R2 1 QEQPSIESTSPISR 14 0 Q5T5P2;Q5T5P2-3 Q5T5P2 KIAA1217 Sickle tail protein homolog 1 QEQPS(0.012)IES(0.006)T(0.192)S(0.79)PISR 131.86 1.505e-05 3011300.0 12914.0 17411.0 16151.0 15178.0 17713.0 17153.0 16881.0 24668.0 20319.0 15748.0 True False 17020.383372113236 23038.765259337906 15936.82718712408 11678.946597762397 15253.855698635845 16080.42019840269 18383.376297169765 20856.12741424777 21393.020857939347 15196.667313318138 1.1200076320152657 1.5160406413021275 1.0487054074782092 0.7685202523007882 1.0037632188781016 1.0581543878577933 1.2096978842893298 1.372414555392008 1.4077442387115244 1.0 13.891467349420806 -7.45692254481016 4.172722637139307 1.2932975964257716 1.0866323574145103 0.13142802722716296 0.20041844996085695 0.4368897277698258 14.872193394681315 0.09863456521722314 0.062277911461212365 3.492025892172209e-08 7.45692254481016 -0.20666523901126133 QEQPSIESTS(ph)PISR ddPTM_PC-9_Lapatinib_30min_R1 1 QEQPSIESTSPISR 14 0 Q5T5P2;Q5T5P2-3 Q5T5P2 KIAA1217 Sickle tail protein homolog 1 QEQPS(0.004)IES(0.004)T(0.056)S(0.936)PIS(0.001)R 85.976 0.028037 0.0 15054.0 20215.0 20298.0 18091.0 21422.0 15993.0 21687.0 22473.0 18451.0 16951.0 True False 14839.327199434503 20168.193409505904 18629.176792545866 19421.47248980687 20162.000077272456 15309.016671503892 22809.846744694027 23517.177621719988 16372.85408235641 19880.957764212264 0.7464090701981568 1.0144477770487845 0.9370361837436358 0.976888172096391 1.0141362562303762 0.7700341629949877 1.1473213220016019 1.1828996319308764 0.8235445332432225 1.0 14.279099639890076 -7.2787584005730475 24.989772811845285 1.0536829952836855 0.923607407767302 0.1945883851054261 0.12480436052905602 1371.7306667298105 1979275.0079059824 0.05098407558544323 0.034467978561992865 5.2630997290900045e-08 7.2787584005730475 -0.13007558751638348 QEQS(ph)PNANNDQPEDLIQGCSESDSSVLR ddPTM_PC-9_AZD4547_30min_R2 1 QEQSPNANNDQPEDLIQGCSESDSSVLR 28 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;F5GXF5;Q12830-2 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 QEQS(1)PNANNDQPEDLIQGCSESDSSVLR 87.63799999999999 1.8873000000000002e-07 2050700.0 3255.8 3089.3 3215.7 2780.9 2680.1 4431.3 3114.6 4969.5 4490.2 3219.3 True False 4291.076675153034 4087.8558104458452 3173.057716898945 2139.806469476708 2308.014376893464 4154.210110486903 3391.793366220304 4201.577962749484 4727.542805075016 3106.5932868786576 1.3812804827967948 1.3158644962350732 1.0213946351783523 0.6887951758972201 0.7429406310255812 1.337223681011954 1.0918047690845945 1.3524712039054876 1.5217771908034359 1.0 11.60111766181194 -7.722128674688833 5.360535174689546 1.3286728998219475 1.0690960731056274 0.12017289336509662 0.2509690874016919 0.3598332894365651 24.877113693679334 0.13682490850344567 0.07440155952710323 1.8961440400391285e-08 7.722128674688833 -0.2595768267163201 QERLS(ph)PEVAPPAHR ddPTM_PC-9_AZD4547_30min_R2 4 QERLSPEVAPPAHR 14 1 Q8TAD8 Q8TAD8 SNIP1 Smad nuclear-interacting protein 1 1 QERLS(1)PEVAPPAHR;QERLS(1)PEVAPPAHR;QERLS(1)PEVAPPAHR;QERLS(1)PEVAPPAHR 79.514 0.0059849 159882000.0 158955.0 152768.1 218052.0 237235.0 241555.0 216669.0 171775.0 197305.0 172675.0 187052.0 True False 209499.38353060695 202147.40078198034 215160.48800735435 182544.13599421296 208019.25779280608 203120.65317831966 187062.64222773188 166816.04586785124 181802.24797700086 180503.36641419795 1.160639758096657 1.119909311376034 1.1920026328685156 1.0113059917970288 1.1524397684388217 1.125301190849938 1.0363388004547376 0.9241713835134872 1.0071958855316991 1.0 17.4616662182738 -7.430153027881727 3.3587411884008698 0.9742787116304625 1.1254180425681266 0.656172709360359 0.0490759485555692 0.15000851652482802 3.200999603128728 0.022609558911075762 0.014001719492625216 3.714043381098564e-08 7.430153027881727 0.15113933093766407 QERLS(ph)PEVAPPAHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QERLSPEVAPPAHR 14 1 Q8TAD8 Q8TAD8 SNIP1 Smad nuclear-interacting protein 1 1 QERLS(1)PEVAPPAHR;QERLS(1)PEVAPPAHR;QERLS(1)PEVAPPAHR;QERLS(1)PEVAPPAHR 85.36200000000001 0.0032668 159715000.0 121825.0 108723.0 134533.0 161383.0 145549.0 146139.0 150852.0 138455.0 118916.0 88632.0 True False 142447.5663465719 119516.30091472462 137740.77693924375 152341.233720745 117029.71828223861 138475.21357699347 136562.2064860981 134820.70295519853 120654.92153303052 104700.27998947405 1.3605270813114612 1.1415088949785053 1.3155721928641586 1.4550222190051496 1.117759363145964 1.3225868506838279 1.3043155806252595 1.2876823535596333 1.1523839434351126 1.0 16.675905774765567 -8.532242544391437 2.443356432509599 1.0007654891536195 1.28624246473204 0.49118687116042303 0.09281110974974265 0.24496682346023263 3.469007183421229 0.08700789896044303 0.02369023717180882 2.936009494067042e-09 8.532242544391437 0.28547697557842056 QERLS(ph)PEVAPPAHR ddPTM_PC-9_Lapatinib_30min_R1 3 QERLSPEVAPPAHR 14 1 Q8TAD8 Q8TAD8 SNIP1 Smad nuclear-interacting protein 1 1 QERLS(1)PEVAPPAHR;QERLS(1)PEVAPPAHR;QERLS(1)PEVAPPAHR 99.81299999999999 0.00099669 148065000.0 123823.0 93189.0 131220.0 98927.0 115863.0 102714.0 91596.0 82152.0 93657.0 82556.0 True False 122057.26131364297 92973.22659601532 120431.59812384807 106202.42159079792 109048.1661354224 98321.1616580285 96338.39269732987 85969.0818306206 83108.36240806754 96825.69460104463 1.2605875105421256 0.9602123380482546 1.2437979259541379 1.0968413087909017 1.126231694848548 1.0154449401385213 0.9949672253246143 0.8878746719539992 0.8583296277966582 1.0 16.56310232533974 -7.108926775193881 1.3734233826139661 0.9083818359126433 1.1361362434235915 0.5568063504869296 0.08613561153131992 0.30974033825654196 1.1668149043679583 0.04578275970865586 0.030495791373276706 7.78167744000185e-08 7.108926775193881 0.22775440751094822 QES(ph)ASSPEFRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QESASSPEFRR 11 1 Q9P2G3-2 Q9P2G3-2 1 QES(0.778)AS(0.111)S(0.111)PEFRR 53.013000000000005 0.044277 14243000.0 33711.0 20282.0 26605.0 36964.0 44479.0 45289.0 42471.0 31148.0 32194.0 25993.0 True False 39417.60647740018 22295.46292093165 27239.36410002438 34893.02691890492 35763.65924517309 42913.965113272054 38447.83941658764 30330.39800403401 32664.77634493581 30705.325139525212 1.2837384492196808 0.7261106280301841 0.887121825815181 1.136383567356827 1.1647380082335157 1.397606601404502 1.252155423916874 0.9877895077226009 1.0638147030362597 1.0 14.906201259449942 -5.817979873674335 6.755358853959849 1.159914150450852 0.9420666831316115 0.17482213694540605 0.17211486339249982 0.2974134156539363 27.63200765244638 0.04980931086357192 0.07502726861144376 1.520617997456979e-06 5.817979873674335 -0.21784746731924065 QES(ph)DEESRPQNANYPR ddPTM_PC-9_Lapatinib_30min_R1 1 QESDEESRPQNANYPR 16 1 O15164-2;O15164 O15164-2 TRIM24 Transcription intermediary factor 1-alpha 1 QES(0.867)DEES(0.04)RPQNANY(0.094)PR 56.081 0.029726 6652400.0 6335.1 5195.2 9883.7 5845.5 6491.2 7466.4 6822.3 6618.3 7648.5 5282.0 True False 6244.7603122849405 5183.170833592135 9071.100338185317 6275.397570016358 6109.400378190218 7147.079477028496 7175.525312229728 6925.810379292015 6787.045387724399 6194.986662177409 1.0080345048055417 0.8366718309883104 1.464264708359681 1.0129799969271744 0.9861845894665561 1.1536876294930465 1.158279380331657 1.1179701841129932 1.0955706215094405 1.0 12.596885460905087 QES(ph)DPEDDDVKKPALQSSVVATSK ddPTM_PC-9_AZD4547_30min_R2 2 QESDPEDDDVKKPALQSSVVATSK 24 2 Q9H307 Q9H307 PNN Pinin 1 QES(0.989)DPEDDDVKKPALQS(0.005)S(0.005)VVATSK;QES(0.995)DPEDDDVKKPALQS(0.002)S(0.002)VVATSK 53.968 0.0031052 328140000.0 180734.0 225357.0 197229.0 208710.0 213153.0 239889.0 227687.0 221934.0 206823.0 209011.0 True False 238203.6524992651 298199.24315367354 194613.61459286083 160595.1340373561 183560.38523860008 224888.70290763263 247950.70191183515 187639.19983596852 217755.2415424768 201693.5885079976 1.1810174743845157 1.4784765612013953 0.9648973774153657 0.7962332130899051 0.9100952915581721 1.1150017438393451 1.2293434994439765 0.9303181188058847 1.0796339296320385 1.0 17.621805698324557 -5.273767914452457 24.984987542756755 1.0020557532891088 1.3297470195530454 0.4979361066315726 0.1311589784820392 560.1043781732437 1135106.948002254 0.036567428506425324 0.07698772987247524 5.3239269216957e-06 5.273767914452457 0.32769126626393663 QES(ph)DPEDDDVKKPALQSSVVATSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QESDPEDDDVKKPALQSSVVATSK 24 2 Q9H307 Q9H307 PNN Pinin 1 QES(0.961)DPEDDDVKKPALQS(0.019)S(0.019)VVATSK;QES(0.987)DPEDDDVKKPALQS(0.006)S(0.006)VVAT(0.001)SK;QES(0.985)DPEDDDVKKPALQS(0.007)S(0.007)VVAT(0.001)SK 54.31100000000001 0.0027559999999999998 91146000.0 80726.0 80771.0 65394.0 88563.0 91687.0 78737.0 87051.0 80519.0 63978.0 72313.0 True False 94391.31738882272 88789.41108305746 66953.24096812597 83601.10223512017 73721.59053063656 74607.89311143331 78804.89908533744 78405.46156693232 64913.55721551537 85422.77447060686 1.104990068208354 1.0394114641360546 0.7837867756351549 0.9786746304275856 0.8630203243515983 0.8733958077784649 0.9225279742283884 0.9178519669120659 0.7599092586000176 1.0 16.382333135993356 -5.082323160808169 5.680211995400757 0.8879572611804399 1.0905066466172368 0.5238804825259946 0.07162401402315952 0.14176064191908275 7.406215494557979 0.01708597738609146 0.048310300255761024 8.273263167496269e-06 5.082323160808169 0.2025493854367969 QES(ph)DPEDDDVKKPALQSSVVATSK ddPTM_PC-9_Lapatinib_30min_R1 4 QESDPEDDDVKKPALQSSVVATSK 24 2 Q9H307 Q9H307 PNN Pinin 1 QES(0.958)DPEDDDVKKPALQS(0.02)S(0.02)VVAT(0.001)S(0.001)K;QES(1)DPEDDDVKKPALQSSVVATSK;QES(0.939)DPEDDDVKKPALQS(0.045)S(0.016)VVATSK;QES(0.995)DPEDDDVKKPALQS(0.004)S(0.001)VVATSK 71.118 0.0018302 261582000.0 493305.0 363338.0 362171.0 332362.0 347601.0 352445.0 297626.0 317064.0 326459.0 275626.0 True False 486270.38023894175 362496.71318442107 332394.6984004896 356805.01020713075 327155.7925898598 337371.7489394231 313035.61798479734 331795.95093903865 289689.7496543274 323267.5868514407 1.5042348816196343 1.1213518704892869 1.0282339211238127 1.1037450852476043 1.012027824305831 1.0436299915662872 0.9683482994187551 1.0263817482311246 0.8961298980694152 1.0 18.30236933410319 -1.9836823453618806 1.0234087633506577 1.0035074722900188 199.99947736003335 0.8999047450628145 0.049571650115040035 185.20370285678905 0.6602843877534174 0.015610004823087725 85905.36474958743 0.010382875695417085 1.9836823453618806 198.99596988774334 QES(ph)VELTVQQK ddPTM_PC-9_AZD4547_30min_R2 1 QESVELTVQQK 11 0 P98174 P98174 FGD1 FYVE, RhoGEF and PH domain-containing protein 1 1 QES(0.995)VELT(0.005)VQQK 86.738 0.010754000000000001 5181600.0 17617.0 19907.0 31655.0 48833.0 39187.0 35664.0 28636.0 45845.0 31991.0 33872.0 True False 23218.83954363625 26341.54844739761 31235.234016990416 37575.30631232913 33746.561466857274 33433.92444212871 31184.548524717356 38760.70866329612 33681.978949079064 32686.151589834386 0.7103570905195663 0.8058932350907291 0.9556106331803462 1.1495787813703742 1.0324421758281475 1.0228773598580165 0.954059961418522 1.1858449764808336 1.030466338519778 1.0 14.996391906269354 -5.272237659177076 2.3369455560912593 1.0551237680486867 0.7258557172332372 0.7567668681281099 0.06666795007939848 0.14806746167189155 1.5202603241415886 0.018408344060554627 0.06307507052716893 5.342719095129138e-06 5.272237659177076 -0.3292680508154495 QES(ph)VELTVQQK ddPTM_PC-9_Lapatinib_30min_R1 1 QESVELTVQQK 11 0 P98174 P98174 FGD1 FYVE, RhoGEF and PH domain-containing protein 1 1 QES(1)VELTVQQK 79.88600000000001 0.046189 0.0 14629.0 18770.0 21155.0 14203.0 20483.0 20094.0 22312.0 26198.0 24653.0 19024.0 True False 14420.387777369966 18726.539218225374 19415.717560661516 15247.53599981907 19278.230211127408 19234.626461401826 23467.206186545543 27415.25472050107 21876.319532401074 22312.273052113407 0.646298462899282 0.8392932075762495 0.8701810665060173 0.6833699087585714 0.8640191058123226 0.86206485625542 1.0517622355971814 1.2287073870272627 0.9804612681686844 1.0 14.44554987448365 -7.136809953737692 2.1891430471276334 1.0900860123235494 0.7827461311662999 0.6802954527325242 0.09223300763480789 0.17859569466511707 1.6789228879404514 0.041576841974289236 0.029631368080701534 7.297767890291572e-08 7.136809953737692 -0.30733988115724953 QESCLGNS(ph)PPFEK ddPTM_PC-9_Lapatinib_30min_R1 1 QESCLGNSPPFEK 13 0 Q86W56;Q86W56-3;Q86W56-2 Q86W56 PARG Poly(ADP-ribose) glycohydrolase 1 QES(0.006)CLGNS(0.994)PPFEK 79.02199999999999 0.014343 8331300.0 30885.0 38571.0 37166.0 35816.0 39793.0 41085.0 36517.0 35227.0 36489.0 28328.0 True False 30444.574236384648 38481.691219295164 34110.35494490881 38450.0281186735 37452.45397604813 39327.89032381279 38407.67158094673 36863.77502248609 32379.224573795604 33224.457055312676 0.9163302258243068 1.1582338623391242 1.0266640290952318 1.1572808565287072 1.1272555609771622 1.1837030251040372 1.1560059963359204 1.109537319484698 0.974559930953577 1.0 15.01995800312891 -4.751969498869972 24.93532945498531 1.1075052665828446 0.9163298355019861 0.3740280800631022 0.07026434750513476 382.19035624309123 1006279.7972573928 0.01720452687816381 0.2156286431462901 1.7702332799970762e-05 4.751969498869972 -0.19117543108085855 QESDPEDDDVKKPALQS(ph)SVVATSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QESDPEDDDVKKPALQSSVVATSK 24 2 Q9H307 Q9H307 PNN Pinin 1 QES(0.151)DPEDDDVKKPALQS(0.623)S(0.215)VVAT(0.008)S(0.003)K;QES(0.022)DPEDDDVKKPALQS(0.477)S(0.477)VVAT(0.011)S(0.012)K 59.918 0.012695999999999999 29619000.0 48852.0 43688.0 34945.0 47265.0 62390.0 44543.0 53811.0 54367.0 39586.0 40737.0 True False 57121.678729018815 48025.055916066514 35778.221329650485 44616.895285197475 50165.12737036241 42207.086666530005 48713.63252209733 52939.92385659806 40164.87036064571 48122.295626085426 1.1870106773970097 0.997979321045395 0.7434853400937164 0.9271564189679307 1.0424508373447097 0.8770796595923618 1.0122882104504458 1.1001121864165841 0.8346416112965677 1.0 15.554417846032116 QESLGLELK ddPTM_PC-9_Lapatinib_30min_R1 1 QESLGLELK 9 0 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 0 90.709 0.038537 13113000.0 29981.0 36335.0 43694.0 35642.0 48410.0 34607.0 32329.0 40839.0 43502.0 32975.0 False True 29553.46544215795 36250.868539915755 40101.64798371756 38263.23157822651 45562.61897772192 33126.939282857194 34002.83743298813 42736.52903009933 38602.34666363168 38674.684813574386 0.7641553017074625 0.9373280923854381 1.0368965688284633 0.9893611741807017 1.178099296667828 0.8565535683753008 0.8792014103513396 1.1050259164645935 0.99812957363993 1.0 15.239101913764262 -4.802925168984079 2.7821878403551796 1.0046980821718967 0.7257114063603477 0.40056418233049484 0.08909807182500236 0.4333645709327464 4.772533194738945 0.023651684904027123 0.27489749727659707 1.5742540926064455e-05 4.802925168984079 -0.278986675811549 QESTEYRR ddPTM_PC-9_Lapatinib_30min_R1 2 QESTEYRR 8 1 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 0 ; 109.48 0.0023902 6040200.0 22299.0 18314.5 20342.3 20751.1 25658.0 25269.0 19063.1 28598.0 35886.0 24906.0 False True 21981.012170864233 18272.093900489526 18669.834617548797 22277.20511764033 24148.84688556887 24188.303774916018 20050.09404153533 29926.767482131803 31844.140783667102 29210.968914841047 0.7524917175786137 0.6255216646102462 0.6391378071702142 0.7626315026586495 0.826704754504042 0.8280555104293993 0.6863892156397658 1.024504444524847 1.0901432566821923 1.0 14.834222592062757 -7.769813626929426 21.89694559460489 1.0429937470153834 0.7324941266553336 0.8109682310384407 0.06783314731948736 18.478182995988856 48312.44043181059 0.04060789846891415 0.02012925921991919 1.6989725928923937e-08 7.769813626929426 -0.31049962036004974 QET(ph)ARAVGR ddPTM_PC-9_Lapatinib_30min_R1 1 QETARAVGR 9 1 H0YEX1;Q8NCM8-3;Q8NCM8;Q8NCM8-2 H0YEX1 DYNC2H1 Cytoplasmic dynein 2 heavy chain 1 1 QET(1)ARAVGR 101.6 0.035503 13664000.0 36493.0 23439.0 27849.0 29615.0 31615.0 24184.0 24813.0 19282.0 29673.0 20267.0 True False 35972.60312800342 23384.728435587855 25559.36272024878 31792.985892743924 29755.467857481497 23149.706695657493 26097.695729058567 20177.91211240177 26330.914269457568 23770.123945919993 1.5133536202775213 0.9837865586561955 1.0752725891711599 1.3375187258205699 1.2518011233420117 0.9738992841739477 1.0979200524336385 0.8488770255598601 1.10773146700302 1.0 14.53686180557687 -6.762748450713651 24.984709183213706 1.0020050119824266 1.2156542221621693 0.36294805526386065 0.14928899624772357 42.21641250564256 805724.5918569011 0.05081987875881909 0.047292549851898465 1.726837810387556e-07 6.762748450713651 0.2136492101797427 QET(ph)VECLR ddPTM_PC-9_Lapatinib_30min_R1 1 QETVECLR 8 0 Q5SWX3;Q13555-5;Q13555-11;Q8WU40;Q13555-10;Q13555-4;Q13555-6;H0Y6G2;A0A2Q3DQE3;Q13555-3;Q13555-7;Q13555-9;Q13555-2;Q13555-8;Q13555 Q5SWX3;Q13555-6 CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 1 QET(1)VECLR 97.45200000000001 0.014203 8927100.0 28016.0 19623.0 59936.0 27297.0 32264.0 29347.0 23910.0 23503.0 50757.0 19375.0 True False 27616.486702494825 19577.564149133526 55008.2934396506 29304.512440122588 30366.294953464578 28091.89722119831 25147.942807471485 24595.03518191986 45040.2121650948 22723.94293443531 1.215303470096533 0.861539047410041 2.4207195731112483 1.2895874859690502 1.3363127623176803 1.236224598092461 1.1066716229674607 1.0823401226135427 1.9820597285888253 1.0 14.471925564674319 -5.93419967497094 24.999999986513433 1.2854777810284674 1.5053738565747836 0.04401081557286601 0.44513964590854255 208.22594870972316 79109.60397901511 0.1261678180410512 0.18713710440226944 1.1635909238241052e-06 5.93419967497094 0.21989607554631618 QETVADFT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 QETVADFTPK 10 0 O75400-2;O75400-3;O75400;F5H578 O75400-2 PRPF40A Pre-mRNA-processing factor 40 homolog A 1 QET(0.114)VADFT(0.886)PK;QETVADFT(1)PK 124.51 0.0010029 29222000.0 222550.0 329610.0 227070.0 105902.0 165707.0 253310.0 304210.0 296500.0 310810.0 185418.0 True False 293316.2706724322 436149.9866251427 224058.90343509745 81487.93006958986 142701.44336102612 237470.4856560006 331284.10066714167 250682.73789218735 327238.7820688092 178926.57225684667 1.639310846749921 2.4375920307636325 1.2522393997100885 0.45542665374830427 0.797541927736592 1.327195187728265 1.851508674695829 1.4010369434246785 1.8288998550705056 1.0 17.449008131342765 -7.040348166410893 23.383137792113896 1.558862834167697 1.3008162592255728 0.03070817885619037 0.5360004057371707 997.5152211680094 578089.8208149996 0.2297002356160498 0.17796389344867963 9.112799889581256e-08 7.040348166410893 -0.25804657494212435 QETVADFT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QETVADFTPK 10 0 O75400-2;O75400-3;O75400;F5H578 O75400-2 PRPF40A Pre-mRNA-processing factor 40 homolog A 1 QETVADFT(1)PK;QET(0.002)VADFT(0.998)PK;QETVADFT(1)PK;QET(0.008)VADFT(0.992)PK 117.7 0.0022852 38339600.0 318839.0 710220.0 411140.0 296047.0 356024.0 208569.0 342384.0 153638.0 201004.0 241250.0 True False 372812.14534270135 780725.9479195375 420943.1368571323 279460.446387324 286263.65293966886 197631.27447525976 309950.9088745015 149605.16529291664 203943.3032377923 284986.71526605054 1.3081737687129065 2.739516988329395 1.4770623131122413 0.9806086789920455 1.0044806919242752 0.6934753933731973 1.0875977449866234 0.5249548743114293 0.7156238951257787 1.0 18.120535143656326 -5.61812084972088 3.143906794855399 0.8409889794088399 2.0443571340304203 0.6237898791795823 0.3640327702616083 0.13808390728951547 2.7094535074980444 0.09627709041423452 0.18606762088894482 2.4092349253908126e-06 5.61812084972088 1.2033681546215804 QETVADFT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 QETVADFTPK 10 0 O75400-2;O75400-3;O75400;F5H578 O75400-2 PRPF40A Pre-mRNA-processing factor 40 homolog A 1 QETVADFT(1)PK;QET(0.199)VADFT(0.801)PK 118.08 0.0022083000000000003 26051200.0 166691.0 289260.0 172037.0 205437.0 259821.0 207694.0 285888.0 276205.0 190525.0 218651.0 True False 164313.95577261463 288590.2362420817 157892.78194202445 220545.52229774182 244538.83960773994 198811.41177836104 300689.8817792724 289038.49263592635 169066.0681828059 256444.5340158561 0.640738771848633 1.1253514813625858 0.6156995412203321 0.8600125681918623 0.9535739981598514 0.7752608669992882 1.1725337915008185 1.1270994476257972 0.6592695330069014 1.0 17.968287295772484 -7.233141000456104 24.976524814486442 1.0003173889919243 0.8393886014171624 0.14864088772306505 0.1873219936446932 1384.704169006514 1222160.02354229 0.06928006091452239 0.05365440750778126 5.846002537685124e-08 7.233141000456104 -0.16092878757476192 QEYDESGPS(ph)IVHR ddPTM_PC-9_AZD4547_30min_R2 3 QEYDESGPSIVHR 13 0 P60709;Q6S8J3;A5A3E0;P0CG38;P0CG39;Q9BYX7;A0A2R8YFE2;P63261 P60709;P63261 ACTB;POTEE;POTEF;POTEI;POTEJ;POTEKP;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;POTE ankyrin domain family member J;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 QEYDESGPS(1)IVHR;QEYDESGPS(1)IVHR;QEYDES(0.017)GPS(0.983)IVHR 163.0 0.00019211 27516000.0 112388.7 181327.0 172497.0 171899.0 201315.0 211804.0 150117.0 231868.0 176245.0 167117.0 True False 148125.9687698172 239937.40670725214 170209.57707246236 132270.3413630754 173365.88719984624 198559.86239739295 163477.12218483724 196038.12839657906 185560.9508887014 161266.28469645578 0.9185178975793236 1.4878336606989828 1.055456677710658 0.8201983546160431 1.0750287174170658 1.2312546467547956 1.0137092355822719 1.215617565479187 1.150649382404849 1.0 17.29908532591579 QEYDESGPS(ph)IVHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QEYDESGPSIVHR 13 0 P60709;Q6S8J3;A5A3E0;P0CG38;P0CG39;Q9BYX7;A0A2R8YFE2;P63261 P60709;P63261 ACTB;POTEE;POTEF;POTEI;POTEJ;POTEKP;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;POTE ankyrin domain family member J;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 QEYDESGPS(1)IVHR;QEYDESGPS(1)IVHR 182.28 4.0347e-05 17108800.0 113676.0 145828.0 155684.0 143666.0 168627.0 120745.0 162987.0 109901.0 114086.0 102085.0 True False 132919.10159665826 160304.84009632276 159396.09699485762 135616.8597914563 135585.7498490483 114412.91964057562 147547.69143630666 107016.21519973499 115754.29192049272 120592.20239558462 1.1022197037304045 1.32931347891356 1.3217778084190108 1.124590621096591 1.1243326446952149 0.9487588531243605 1.223525970214049 0.8874223463361616 0.9598820621981687 1.0 16.879777098682133 -6.273785356136927 1.5353646297553893 1.0081582955591706 1.2552656490710021 0.4903884609449882 0.1048877610890407 0.3324440948592043 1.5630573546697561 0.0390738793783456 0.05281181645813163 5.323713111958838e-07 6.273785356136927 0.24710735351183155 QEYDESGPS(ph)IVHR ddPTM_PC-9_Lapatinib_30min_R1 1 QEYDESGPSIVHR 13 0 P60709;Q6S8J3;A5A3E0;P0CG38;P0CG39;Q9BYX7;A0A2R8YFE2;P63261 P60709;P63261 ACTB;POTEE;POTEF;POTEI;POTEJ;POTEKP;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;POTE ankyrin domain family member J;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 QEYDESGPS(1)IVHR 163.0 0.00019211 15593000.0 37126.0 73981.0 77406.0 56174.0 89773.0 84159.0 85543.0 88664.0 76581.0 68679.0 True False 36596.57643192545 73809.70153987905 71041.97747580064 60305.22335097065 84492.7286405088 80559.71575421096 89971.99797488634 92783.6531238457 67955.64134631916 80550.07364098476 0.4543332461126977 0.9163207208084273 0.8819604286451416 0.7486675135736522 1.0489466343270724 1.0001197033446447 1.1169697792691726 1.1518754599454066 0.8436446830477208 1.0 16.29759828743145 -4.3552971046786055 0.6401044288281298 1.0303930773101362 1.5154344976126302e-15 0.6046240487914899 0.12182338248103375 4.011982218361527 0.8429358612333807 0.056267874550340484 3.4176526643091383 4.41268468427683e-05 4.3552971046786055 -1.0303930773101346 QEYDESGPSIVHR ddPTM_PC-9_AZD4547_30min_R2 3 QEYDESGPSIVHR 13 0 P60709;Q6S8J3;A5A3E0;P0CG38;P0CG39;Q9BYX7;A0A2R8YFE2;P63261 P60709;P63261 ACTB;POTEE;POTEF;POTEI;POTEJ;POTEKP;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;POTE ankyrin domain family member J;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ;; 243.49 5.1314e-34 287041200.0 206218.0 193940.0 412073.0 547846.0 539648.0 501584.0 458962.0 696960.0 427207.0 460768.0 False True 271791.0343991359 256627.31229659406 406608.6427762846 421548.56883632543 464727.190202531 470219.87318810786 499808.72887279326 589260.8465475171 449788.28985962365 444636.6525668644 0.6112654744724717 0.5771618484780727 0.9144739652679417 0.9480742678381266 1.045184168960622 1.057537363313512 1.1240835095069723 1.3252637701947079 1.0115861732563411 1.0 18.762267352844304 -5.428742693920343 0.8709477460691964 1.1278134309364676 0.47198334318796054 0.8007078785571866 0.09488386399282843 0.42535290302858036 0.4668959234343993 0.03763363015206515 0.2227236291282508 3.7261240222108493e-06 5.428742693920343 -0.655830087748507 QEYDESGPSIVHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QEYDESGPSIVHR 13 0 P60709;Q6S8J3;A5A3E0;P0CG38;P0CG39;Q9BYX7;A0A2R8YFE2;P63261 P60709;P63261 ACTB;POTEE;POTEF;POTEI;POTEJ;POTEKP;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;POTE ankyrin domain family member J;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ;; 203.32 9.1384e-10 201172000.0 87117.0 129378.0 192705.0 190884.0 221933.0 152960.0 183431.0 165365.0 159992.0 129348.0 False True 101864.18746081926 142221.79281058532 197299.81803778265 180189.38833427816 178446.82180937057 144938.50832930923 166055.08775456378 161024.3439687008 162331.58032487307 152797.76848179524 0.6666601775205614 0.9307844886984068 1.2912480332544223 1.1792671458794663 1.167862748143676 0.9485643001820253 1.0867638277999332 1.053839631093079 1.0623949677917823 1.0 17.221263948283273 -4.903452446746223 3.6156207820362782 1.1011594091410886 0.665278863665803 0.6705615657814358 0.09308272518196593 0.148669133818226 3.4241929694579003 0.025006918212935946 0.14332946598254617 1.2489571921875578e-05 4.903452446746223 -0.43588054547528554 QEYDESGPSIVHR ddPTM_PC-9_Lapatinib_30min_R1 5 QEYDESGPSIVHR 13 0 P60709;Q6S8J3;A5A3E0;P0CG38;P0CG39;Q9BYX7;A0A2R8YFE2;P63261 P60709;P63261 ACTB;POTEE;POTEF;POTEI;POTEJ;POTEKP;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;POTE ankyrin domain family member J;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ;;;; 201.3 1.2244e-12 393214400.0 289791.0 343996.0 504369.0 450141.0 548482.0 553889.0 489553.0 493773.0 588139.0 409248.0 False True 285658.52719883877 343199.4983970505 462901.7277406433 483245.8707663561 516221.36711710074 530200.4586483222 514899.6589387748 516715.49618695903 521896.59244176495 479985.97151131794 0.5951393252169309 0.7150198521769879 0.9644067852298225 1.0067916552743694 1.0754926138605456 1.1046165723945958 1.0727389746777913 1.0765220795099322 1.0873163455141912 1.0 18.872632715423087 -5.170405680960608 1.3301716564748243 1.0737398469059696 0.5277736877739454 0.968252052798428 0.02942583197751212 0.10452267030214916 0.2603010488435236 0.008679198440332957 0.06389391332636613 6.754517310623999e-06 5.170405680960608 -0.5459661591320242 QEYDESGPSIVHRK ddPTM_PC-9_AZD4547_30min_R2 2 QEYDESGPSIVHRK 14 1 P60709;Q6S8J3;A5A3E0;P0CG38;P0CG39;Q9BYX7;A0A2R8YFE2;P63261 P60709;P63261 ACTB;POTEE;POTEF;POTEI;POTEJ;POTEKP;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;POTE ankyrin domain family member J;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ; 82.20200000000001 0.0037779000000000003 29472000.0 22209.0 11961.8 74711.0 185955.0 135135.0 72111.0 56968.0 105380.0 52827.0 86253.0 False True 29271.000024102734 15828.217924251812 73720.28332469982 143085.94772611052 116373.83784989314 67601.88777047851 62038.04163836072 89095.94239149625 55619.327371542015 83233.30872337004 0.3516741130811744 0.19016687149681466 0.8857065092739829 1.719094794148622 1.3981642642210377 0.8121975301397267 0.7453511411464752 1.0704361481965228 0.6682340066090076 1.0 16.344873368413772 -5.34629898379836 4.704448790022421 1.067792399312573 0.272054283284288 0.5175400467939295 0.29840646197753284 0.1738081768825413 6.687798098784902 0.0870391146957513 0.19192370997082683 4.505064530625717e-06 5.34629898379836 -0.795738116028285 QEYDESGPSIVHRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QEYDESGPSIVHRK 14 1 P60709;Q6S8J3;A5A3E0;P0CG38;P0CG39;Q9BYX7;A0A2R8YFE2;P63261 P60709;P63261 ACTB;POTEE;POTEF;POTEI;POTEJ;POTEKP;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;POTE ankyrin domain family member J;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ; 85.536 0.0027203 19934400.0 33753.0 19616.5 50919.0 79460.0 106844.0 126895.0 72523.0 115555.0 106590.0 63231.0 False True 39466.71624786235 21563.896479067924 52133.10207138286 75008.11381279565 85908.68518607161 120240.4028141195 65653.09641894914 112521.80369064277 108148.67710153165 74694.27976367953 0.5283766892555706 0.2886954201485383 0.6979530726626384 1.004201580765074 1.1501374062093193 1.6097672163723975 0.878957486793698 1.506431336464363 1.4478843285415746 1.0 16.188710142342238 -5.790435769777592 1.5765799631002864 1.294046189431839 0.3948203497164383 0.7133683338594408 0.21973096675061585 0.19697884373788122 0.9941539771661999 0.0695322473181237 0.14914211442439704 1.6201835941333138e-06 5.790435769777592 -0.8992258397154006 QEYDESGPSIVHRK ddPTM_PC-9_Lapatinib_30min_R1 2 QEYDESGPSIVHRK 14 1 P60709;Q6S8J3;A5A3E0;P0CG38;P0CG39;Q9BYX7;A0A2R8YFE2;P63261 P60709;P63261 ACTB;POTEE;POTEF;POTEI;POTEJ;POTEKP;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;POTE ankyrin domain family member J;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ; 73.92699999999999 0.007679000000000001 21115200.0 207590.0 56681.0 149309.0 96576.0 88469.0 113808.0 45335.0 36728.0 180146.0 52675.0 False True 204629.72853265595 56549.75862697028 137033.39036940702 103678.52120809167 83265.42735674621 108940.69713940562 47682.22447414135 38434.51696215601 159856.0604585213 61779.8035649744 3.312243107368332 0.9153437752112042 2.2180936562106046 1.6781944134712568 1.3477774701755918 1.7633707272123593 0.7718092600277291 0.6221210613228007 2.58751325245635 1.0 15.914847663330024 -4.7514033656537125 24.988218114231877 1.4410636749296768 3.312246935068644 0.46342357862156436 0.6063353549690662 376.17786253177155 936564.1252223062 0.14765180529704003 1.960294036923203 1.772542407552264e-05 4.7514033656537125 1.871183260138967 QFAS(ph)QANVVGPWIQTK ddPTM_PC-9_AZD4547_30min_R2 1 QFASQANVVGPWIQTK 16 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 1 QFAS(1)QANVVGPWIQTK 147.25 4.0832e-10 0.0 10129.0 10298.0 15343.0 21278.0 19775.0 11999.0 11052.0 17955.0 13938.0 14570.0 True False 13349.811303711851 13626.627111634132 15139.541795061883 16372.685841822928 17029.582591346687 11248.700633162354 12035.606589439041 15180.46731485401 14674.73422500904 14059.908734762843 0.949494876215285 0.9691831838099041 1.0767880560724885 1.1644944608596064 1.2112157278262685 0.8000550249199105 0.8560230949210392 1.0796988516234538 1.043728981591897 1.0 13.77929960921364 -6.756460916259038 24.999998577741778 0.9546399949482919 1.0735552249053613 0.23683721901384824 0.10619382350217062 216.17818777412097 1085567.2823570298 0.03976988013296668 0.03859073583524101 1.752020097778855e-07 6.756460916259038 0.11891522995706938 QFAS(ph)QANVVGPWIQTK ddPTM_PC-9_Lapatinib_30min_R1 1 QFASQANVVGPWIQTK 16 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 1 QFAS(1)QANVVGPWIQTK 156.39 9.2351e-15 0.0 6296.0 6208.0 7152.3 5734.7 5387.6 7366.8 6089.1 6788.5 8687.4 4391.9 True False 6206.2178854550075 6193.62575741838 6564.265502676408 6156.4489683983975 5070.711960429141 7051.739136849549 6404.363803804883 7103.918492637659 7708.933529622403 5151.034063161101 1.204848931176813 1.2024043486168403 1.2743587835348211 1.1951870037955623 0.9844066061790577 1.368994856252614 1.243316142987149 1.379124736029819 1.4965798003074287 1.0 12.330646365121487 QFASQANVVGPWIQTK ddPTM_PC-9_Lapatinib_30min_R1 2 QFASQANVVGPWIQTK 16 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ; 198.59 2.2335999999999995e-11 7338600.0 28826.0 24276.0 25882.0 28491.0 31444.0 21469.0 28212.0 26696.0 31185.0 26204.0 False True 28414.93595395901 24219.790413513005 23754.08186740921 30586.323183189816 29594.52574128255 20550.820916683362 29672.679317623846 27936.39361853943 27672.616907391697 30733.326485364763 0.9245642826034542 0.7880627703950788 0.7729095605293793 0.9952168112278718 0.9629457375977666 0.6686819575638739 0.9654886961798295 0.908993487309054 0.9004107290686357 1.0 14.9075163080231 -8.817656842895396 0.5169562262896495 1.0051020757087656 0.8571452174383415 0.14813811091672147 0.09632525336951703 2.9108423873234193 1.626669202683031 0.13239082965514395 0.05142723019364017 1.521749462771574e-09 8.817656842895396 -0.14795685827042415 QFCQEGQPHVLEALS(ph)PPQTSGLS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 3 QFCQEGQPHVLEALSPPQTSGLSPSR 26 0 E9PR76;E9PSH4;Q9H063 E9PR76 MAF1 Repressor of RNA polymerase III transcription MAF1 homolog 2 QFCQEGQPHVLEALS(0.993)PPQT(0.149)S(0.129)GLS(0.419)PS(0.309)R;QFCQEGQPHVLEALS(0.982)PPQT(0.177)S(0.154)GLS(0.592)PS(0.096)R;QFCQEGQPHVLEALS(0.99)PPQT(0.268)S(0.236)GLS(0.47)PS(0.035)R 76.48100000000001 0.00015178 18286600.0 38944.5 33023.6 52986.0 69980.0 68058.0 65488.0 53244.0 66093.0 49466.0 62031.0 True False 51328.04090407802 43697.83288830459 52283.37101956263 53847.19218022221 58609.32146659281 61393.025007462005 57982.61285270466 55879.84551604829 52080.67177315949 59859.31357076692 0.8574779402272454 0.7300089206108938 0.873437530447992 0.8995624735416143 0.9791178343083345 1.025621934920485 0.9686481416823535 0.9335196510395326 0.8700512696589586 1.0 15.869288114554381 -5.727557175819943 2.0244467469182292 0.96127560340561 0.7950384054167674 0.6225290974133386 0.05077349791656822 0.2083522232657141 1.7382799647550389 0.015787678111789907 0.032100867179570745 1.8725905361423575e-06 5.727557175819943 -0.16623719798884262 QFCQEGQPHVLEALS(ph)PPQTSGLS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 2 QFCQEGQPHVLEALSPPQTSGLSPSR 26 0 E9PR76;E9PSH4;Q9H063 E9PR76 MAF1 Repressor of RNA polymerase III transcription MAF1 homolog 2 QFCQEGQPHVLEALS(0.994)PPQT(0.092)S(0.093)GLS(0.647)PS(0.175)R;QFCQEGQPHVLEALS(0.975)PPQT(0.247)S(0.248)GLS(0.42)PS(0.11)R 60.196999999999996 0.005520199999999999 6869900.0 15374.2 15669.0 16805.7 15202.6 24028.0 29883.0 23597.0 30466.0 32066.0 22441.0 True False 15154.961088717022 15632.719393200483 15424.000217878009 16320.649918386922 22614.720280865586 28604.973750675344 24818.737198992243 31881.561581601065 28454.38941005042 26319.896949247108 0.5757986483739077 0.5939506307089726 0.5860205398075929 0.6200879110529262 0.8592252592961801 1.086819367333944 0.9429648317715846 1.2113102738615795 1.0810980553958578 1.0 14.683866220024534 -6.456444314831147 1.979714494853201 1.0761141579548898 0.5825938053649976 0.9178899865084321 0.0662309328826668 0.08444383803030969 0.6591901415599277 0.02387662524259942 0.027085451505901303 3.4958733075656866e-07 6.456444314831147 -0.49352035258989224 QFCQEGQPHVLEALS(ph)PPQTSGLSPSR ddPTM_PC-9_AZD4547_30min_R2 1 QFCQEGQPHVLEALSPPQTSGLSPSR 26 0 E9PR76;E9PSH4;Q9H063 E9PR76 MAF1 Repressor of RNA polymerase III transcription MAF1 homolog 1 QFCQEGQPHVLEALS(0.982)PPQT(0.008)S(0.008)GLS(0.001)PS(0.001)R 97.48200000000001 2.095e-09 8243100.0 9428.8 8626.2 12170.0 18026.0 13405.0 10931.0 11601.0 13927.0 10335.0 11592.0 True False 12426.962268776617 11414.450455464967 12008.617848263262 13870.384198923777 11543.947137142979 10247.48284199497 12633.466525885115 11774.902160622214 10881.28700067932 11186.1676083302 1.1109222303733775 1.0204076011667094 1.0735238616772194 1.2399585527928862 1.0319841022716614 0.9160852224638397 1.1293829100573398 1.0526305856398566 0.9727448561182079 1.0 13.449428231818695 -6.492506588549998 24.977072886668957 1.0190340577741488 1.106269432665088 0.2875026845724026 0.07262781837348718 1016.355480418916 835818.3198599075 0.023348586988447693 0.026441080818123717 3.2173137234336827e-07 6.492506588549998 0.08723537489093913 QFCQEGQPHVLEALS(ph)PPQTSGLSPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QFCQEGQPHVLEALSPPQTSGLSPSR 26 0 E9PR76;E9PSH4;Q9H063 E9PR76 MAF1 Repressor of RNA polymerase III transcription MAF1 homolog 1 QFCQEGQPHVLEALS(0.977)PPQT(0.011)S(0.011)GLSPSR;QFCQEGQPHVLEALS(0.933)PPQT(0.019)S(0.019)GLS(0.019)PS(0.011)R 114.24 7.1466e-12 52202000.0 80704.0 78412.0 86190.0 98373.0 114808.0 97115.0 94266.0 90135.0 88132.0 69901.0 True False 94365.59322334283 86196.22515314503 88245.09647739545 92861.4797395693 92312.19655612411 92022.11843881333 85336.44205326092 87769.05175592673 89420.76377063684 82573.49796398857 1.1428072632274455 1.0438727591598018 1.0686854578436333 1.124591812497364 1.1179397607254413 1.114426791982888 1.0334604220167263 1.0629203548359307 1.0829232862296139 1.0 16.33339120125536 -9.029468832563808 0.45236586886600927 0.9942078002224789 1.0981795605114208 0.42643421127012926 0.03288133904530464 2.2818355261848473 0.8643649510997798 0.06735857125820811 0.021175549919466737 9.343964234402321e-10 9.029468832563808 0.10397176028894195 QFCQEGQPHVLEALSPPQT(ph)SGLSPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QFCQEGQPHVLEALSPPQTSGLSPSR 26 0 E9PR76;E9PSH4;Q9H063 E9PR76 MAF1 Repressor of RNA polymerase III transcription MAF1 homolog 1 QFCQEGQPHVLEALSPPQT(0.25)S(0.25)GLS(0.25)PS(0.25)R;QFCQEGQPHVLEALS(0.171)PPQT(0.457)S(0.268)GLS(0.084)PS(0.02)R;QFCQEGQPHVLEALS(0.001)PPQT(0.291)S(0.291)GLS(0.209)PS(0.209)R;QFCQEGQPHVLEALS(0.014)PPQT(0.334)S(0.334)GLS(0.277)PS(0.04)R 114.68 2.5351999999999996e-11 15789600.0 86700.4 88894.6 108006.0 117077.0 124566.0 95549.3 103479.0 92200.0 80074.8 72780.0 True False 101377.06530904431 97719.4684040554 110581.27265503583 110517.55525875528 100158.18650451304 90538.5265030707 93676.71999691745 89779.84769397523 81245.74246336159 85974.43787383713 1.1791535695506343 1.1366107278009014 1.2862110574925527 1.2854699372496492 1.1649763462424703 1.0530865771513518 1.0895880486521239 1.0442621076013585 0.9449988214239371 1.0 16.39162015756783 -6.728182610385851 2.501967337115648 1.0269361923808926 1.2214709207194876 0.7496999679295946 0.054102717095055236 0.16079839144414593 2.062058550971746 0.022182678715424113 0.020952001213776047 1.8698957288565574e-07 6.728182610385851 0.19453472833859498 QFCQEGQPHVLEALSPPQTSGLS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 2 QFCQEGQPHVLEALSPPQTSGLSPSR 26 0 E9PR76;E9PSH4;Q9H063 E9PR76 MAF1 Repressor of RNA polymerase III transcription MAF1 homolog 1 QFCQEGQPHVLEALSPPQT(0.085)S(0.085)GLS(0.754)PS(0.077)R;QFCQEGQPHVLEALS(0.004)PPQT(0.051)S(0.051)GLS(0.706)PS(0.188)R 196.72 9.4366e-32 86890000.0 163101.0 158007.0 289740.0 372250.0 283910.0 272350.0 213872.0 303090.0 231920.0 232040.0 True False 214963.7252884502 209079.6727547069 285897.85828724713 286433.5137051687 244493.99714332423 255319.9114461013 232906.19367503672 256254.40481532193 244178.81772593604 223916.35022747942 0.9600179936394366 0.9337400888425532 1.276806530638785 1.2791987428080946 1.0918988135298728 1.1402468430140034 1.0401482224876586 1.1444202469135902 1.0904912369189286 1.0 17.772600351135033 -5.233995195210307 24.585817783943344 1.1387694601538636 0.9468789457652979 0.43122291475212604 0.08524362936935051 565.2169990517056 506346.0810412386 0.02255954452775033 0.05965118931548882 5.834515592176773e-06 5.233995195210307 -0.19189051438856575 QFCQEGQPHVLEALSPPQTSGLS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QFCQEGQPHVLEALSPPQTSGLSPSR 26 0 E9PR76;E9PSH4;Q9H063 E9PR76 MAF1 Repressor of RNA polymerase III transcription MAF1 homolog 1 QFCQEGQPHVLEALS(0.001)PPQT(0.101)S(0.101)GLS(0.679)PS(0.117)R 103.4 7.2608e-10 28546000.0 14156.0 16070.0 22076.0 25695.0 24624.0 20841.0 22200.0 20686.0 15852.0 14042.0 True False 16552.33120625544 17665.323397069882 22602.375563696223 24255.392454313973 19799.10396486302 19748.061271516326 20097.055285918515 20143.014418628714 16083.805510962367 16587.703443589166 0.9978675627127035 1.0649649878987435 1.3625982427622683 1.462251392231649 1.1936012741121798 1.1905241336556798 1.2115634544748055 1.2143341293223813 0.969622200303952 1.0 14.017826539508583 -8.25816379569353 22.833930437798553 0.9848110242445848 1.2192873225284617 0.3477380366490336 0.12427564010430633 95.96290399952004 668997.93438104 0.10194746618399113 0.03474303920015899 5.5186926059012555e-09 8.25816379569353 0.23447629828387695 QFCQEGQPHVLEALSPPQTSGLS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 2 QFCQEGQPHVLEALSPPQTSGLSPSR 26 0 E9PR76;E9PSH4;Q9H063 E9PR76 MAF1 Repressor of RNA polymerase III transcription MAF1 homolog 1 QFCQEGQPHVLEALSPPQT(0.142)S(0.142)GLS(0.689)PS(0.026)R;QFCQEGQPHVLEALSPPQT(0.129)S(0.129)GLS(0.616)PS(0.127)R 179.95 3.9592000000000005e-18 89327000.0 370120.0 321840.0 360770.0 290390.0 239490.0 285580.0 229193.0 214395.0 247050.0 160242.0 True False 364842.0209283048 321094.7992537906 331108.8832124735 311746.2493126418 225403.6690554561 273366.40911949525 241059.49209003808 224356.5743874274 219224.62744816815 187939.6161909565 1.941272565745831 1.708499813724965 1.761783331918958 1.6587575074958718 1.1993409033379858 1.4545438298742754 1.2826433137178965 1.1937694613543819 1.16646310070903 1.0 17.519909682003686 -5.169313989882712 0.27704901919803787 0.9876885483700871 2.5240001998356005 0.8889430942666716 0.09922847480331488 2.1963391695378056 0.16704057289265434 0.13235228244012118 1.1331706974494078 6.771517577086247e-06 5.169313989882712 1.5363116514655135 QFEDELHPDLK ddPTM_PC-9_Lapatinib_30min_R1 1 QFEDELHPDLK 11 0 Q9Y3C6 Q9Y3C6 PPIL1 Peptidyl-prolyl cis-trans isomerase-like 1 0 62.89 0.044612 3013500.0 35589.0 26509.0 32124.0 30467.0 34290.0 32552.0 28041.0 22503.0 27647.0 26600.0 False True 35081.49433377673 26447.6200392081 29482.88872222601 32707.644814932577 32273.129616733844 31159.82684241824 29492.82577433325 23548.57153124037 24533.10372418338 31197.77455772794 1.1244870773991398 0.8477405973387552 0.9450317896127902 1.0483967295298835 1.034468966913524 0.9987836403125652 0.9453503075919767 0.7548157477600338 0.7863735177260051 1.0 14.929155500013907 -7.590219212817508 5.689790112434062 0.8290346029828736 0.9926111985815653 0.3551371577353819 0.09067352251465423 0.2057513609948513 12.38187468196807 0.04287990927344284 0.02442034250110448 2.5690986870350726e-08 7.590219212817508 0.16357659559869175 QFIAAQNLGPASGHGTPASSPSSSSLPS(ph)PMSPTPR ddPTM_PC-9_AZD4547_30min_R2 2 QFIAAQNLGPASGHGTPASSPSSSSLPSPMSPTPR 35 0 Q8WX93-3;Q8WX93;A0A3B3ISX8;Q8WX93-4 Q8WX93-3 PALLD Palladin 1 QFIAAQNLGPASGHGTPAS(0.003)S(0.003)PS(0.012)S(0.012)S(0.069)S(0.069)LPS(0.358)PMS(0.358)PT(0.116)PR;QFIAAQNLGPASGHGTPAS(0.014)S(0.014)PS(0.117)S(0.117)S(0.117)S(0.117)LPS(0.347)PMS(0.117)PT(0.04)PR 97.59200000000001 4.0716e-16 23118500.0 3106.4 7534.7 29617.1 63792.0 40723.0 32020.0 15186.5 48072.0 20344.1 33518.0 True False 4094.170582866078 9970.144425910823 29224.357902530646 49085.739976575234 35069.314380147196 30017.784338183043 16538.069079851237 40643.57698466509 21419.447592696688 32344.545022085193 0.12657994045272658 0.30824809621230115 0.9035328177464221 1.517589440292296 1.0842420060693851 0.9280632736582501 0.5113093743800963 1.2565821209391947 0.6622275124931041 1.0 14.98123479862399 -5.240994944821103 3.765332576572793 1.0009529947969482 0.17804906768459283 0.5749729971922108 0.2656249306570094 0.15774606171640831 4.981868835288306 0.07232840802761036 0.2010477643915124 5.741231449501124e-06 5.240994944821103 -0.8229039271123554 QFIAAQNLGPASGHGTPASSPSSSSLPSPMS(ph)PTPR ddPTM_PC-9_AZD4547_30min_R2 3 QFIAAQNLGPASGHGTPASSPSSSSLPSPMSPTPR 35 0 Q8WX93-3;Q8WX93;A0A3B3ISX8;Q8WX93-4 Q8WX93-3 PALLD Palladin 1 QFIAAQNLGPASGHGTPAS(0.003)S(0.003)PS(0.006)S(0.017)S(0.017)S(0.017)LPS(0.031)PMS(0.797)PT(0.111)PR;QFIAAQNLGPASGHGTPASSPSSSSLPS(0.002)PMS(0.948)PT(0.049)PR;QFIAAQNLGPASGHGTPAS(0.002)S(0.002)PS(0.008)S(0.016)S(0.016)S(0.016)LPS(0.081)PMS(0.637)PT(0.222)PR 133.28 3.1504000000000003e-22 63995000.0 9830.7 7862.0 86782.0 200208.0 112318.0 73076.0 39954.3 148025.0 65518.0 96033.0 True False 12956.658108737309 10403.237750210474 85631.21397764843 154053.13878276543 96724.58444980433 68506.54616792845 43510.15529826496 125151.13752610798 68981.14772235202 92670.91390017027 0.13981364339079322 0.11226001031367146 0.9240354969402227 1.6623677516412447 1.0437426413426858 0.739245393022962 0.4695125305997982 1.350489946186643 0.7443667578012876 1.0 16.49982897884749 -5.2792604925967845 5.749887691045841 1.005190423883572 0.11980297510209581 0.5501885042241582 0.3133517749281282 0.1183986026555968 14.74794668492869 0.08675473407345902 0.1988903351491098 5.257018524865852e-06 5.2792604925967845 -0.8853874487814762 QFIAAQNLGPASGHGTPASSPSSSSLPSPMS(ph)PTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QFIAAQNLGPASGHGTPASSPSSSSLPSPMSPTPR 35 0 Q8WX93-3;Q8WX93;A0A3B3ISX8;Q8WX93-4 Q8WX93-3 PALLD Palladin 1 QFIAAQNLGPASGHGTPAS(0.001)S(0.001)PS(0.002)S(0.002)S(0.002)S(0.002)LPS(0.003)PMS(0.895)PT(0.092)PR;QFIAAQNLGPASGHGTPAS(0.002)S(0.002)PS(0.038)S(0.038)S(0.038)S(0.038)LPS(0.07)PMS(0.704)PT(0.07)PR 90.79899999999999 2.5935e-12 21246000.0 5389.200000000001 3741.6 26378.0 26497.0 50260.0 63078.0 40610.0 43037.0 56444.0 28305.0 True False 6301.485118448132 4113.041320627047 27006.951559122088 25012.458994433047 40411.91379442887 59770.07863752732 36763.12680906087 41907.32435147074 57269.38671844309 33436.47243774329 0.18846142128722224 0.12301062345273665 0.8077093541912179 0.7480591453241592 1.2086177412905454 1.7875713040248378 1.099491786327389 1.253341674409574 1.712781957638482 1.0 15.029135030047762 -5.69514319244693 1.082885815363252 1.378907111873299 0.07279215228171022 0.7587880107337249 0.25865436889079824 0.28593465628928977 0.6262636915940644 0.09532091664078621 0.30143202975504735 2.0177009921657973e-06 5.69514319244693 -1.3061149595915886 QFIAAQNLGPASGHGTPASSPSSSSLPSPMS(ph)PTPR ddPTM_PC-9_Lapatinib_30min_R1 2 QFIAAQNLGPASGHGTPASSPSSSSLPSPMSPTPR 35 0 Q8WX93-3;Q8WX93;A0A3B3ISX8;Q8WX93-4 Q8WX93-3 PALLD Palladin 1 QFIAAQNLGPASGHGTPASS(0.003)PS(0.022)S(0.022)S(0.022)S(0.022)LPS(0.116)PMS(0.681)PT(0.112)PR;QFIAAQNLGPASGHGTPAS(0.002)S(0.002)PS(0.014)S(0.011)S(0.011)S(0.034)LPS(0.23)PMS(0.611)PT(0.085)PR 147.63 1.2432e-21 15519900.0 15729.1 9292.9 28477.0 10996.3 23415.0 36445.0 22395.0 21648.0 54982.0 22518.5 True False 15504.800149636323 9271.382861004076 26135.730984398884 11805.004584581464 22037.775735661216 34886.33230744447 23554.503520423415 22653.8451099094 48789.348173872415 26410.79272098482 0.5870630356852905 0.351045232112153 0.9895852525332425 0.44697653377142826 0.8344231075711331 1.320911972465157 0.8918514400254285 0.8577495325200778 1.8473261552314788 1.0 14.688839984252866 -6.532616666670939 0.685583119736205 1.247400312562047 0.4994599464367432 0.42889149040332264 0.31174329385829835 0.7556472294033126 0.7898491848976911 0.21442381720677758 0.2845299958922355 2.933481362517499e-07 6.532616666670939 -0.7479403661253038 QFLISPPAS(ph)PPVGWK ddPTM_PC-9_AZD4547_30min_R2 1 QFLISPPASPPVGWK 15 0 H0YF64;V9GYW9;E9PD55;E9PDJ2;Q9UKA8-6;P53805-4;P53805-3;Q9UKA8-5;P53805-2;Q9UKA8-2;Q9UKA8;P53805 H0YF64 RCAN3;RCAN1 Calcipressin-3;Calcipressin-1 1 QFLIS(0.307)PPAS(0.693)PPVGWK 135.69 2.4551e-05 10600000.0 73859.0 69834.0 83057.0 98799.0 103050.0 77678.0 60734.0 69662.0 55647.0 71150.0 True False 97344.62563736348 92406.47482169913 81955.60991152033 76022.41697933368 88743.28627247906 72820.78238043065 66139.20834265197 58897.33857350937 58588.386814397876 68659.06015637447 1.4177972348537278 1.3458744499449704 1.1936605267369271 1.1072452318192063 1.2925211337056137 1.0606143197209175 0.9632990634013426 0.8578232565282384 0.8533234606031581 1.0 16.06716248856297 -6.510821881225368 0.5820258519230211 0.871432218258705 1.3848205879983944 0.7879477330237361 0.08691295978660707 0.4360557885795331 0.3200519247905924 0.0726356836991619 0.10954727515182114 3.084452728677906e-07 6.510821881225368 0.5133883697396894 QFLISPPAS(ph)PPVGWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QFLISPPASPPVGWK 15 0 H0YF64;V9GYW9;E9PD55;E9PDJ2;Q9UKA8-6;P53805-4;P53805-3;Q9UKA8-5;P53805-2;Q9UKA8-2;Q9UKA8;P53805 H0YF64 RCAN3;RCAN1 Calcipressin-3;Calcipressin-1 1 QFLISPPAS(1)PPVGWK 120.59 7.9157e-05 9007200.0 71288.0 73883.0 75695.0 80122.0 90510.0 80731.0 95722.0 73699.0 84868.0 61805.0 True False 83355.65039781963 81217.61596426359 77499.8558748859 75633.02409902877 72775.21523147133 76497.32424119682 86654.51919273402 71764.47934054516 86109.03394551807 73009.75725188917 1.1417056231297462 1.1124213943631767 1.0614999801671106 1.0359303598023089 0.9967875249932876 1.0477685054790045 1.1868895672912512 0.9829436782395029 1.1794181652794078 1.0 16.1558016626961 -7.833156120966143 0.006358856577932452 7.293667171413465e-08 2.1315271946329 0.06222251291751757 0.06978927174256126 9269.352929894008 58.96811308431441 9864.376277741618 9895.652633211044 1.4683983202690083e-08 7.833156120966143 2.1315271216962284 QFLISPPAS(ph)PPVGWK ddPTM_PC-9_Lapatinib_30min_R1 1 QFLISPPASPPVGWK 15 0 H0YF64;V9GYW9;E9PD55;E9PDJ2;Q9UKA8-6;P53805-4;P53805-3;Q9UKA8-5;P53805-2;Q9UKA8-2;Q9UKA8;P53805 H0YF64 RCAN3;RCAN1 Calcipressin-3;Calcipressin-1 1 QFLIS(0.343)PPAS(0.657)PPVGWK 170.0 0.00016234 9931300.0 76422.0 57201.0 65315.0 52985.0 61369.0 68919.0 56491.0 53087.0 73236.0 48160.0 True False 75332.20826592176 57068.554598918934 59945.05282319113 56881.69365277855 57759.39607609623 65971.49502803577 59415.82756741415 55553.61582362163 64987.390470730825 56484.391830833774 1.3336818512897453 1.010342021028299 1.0612675622448366 1.0070338337559632 1.0225726825400012 1.1679597299306173 1.0518981552525128 0.983521536179415 1.1505371371504336 1.0 15.785564646385058 -4.756282679296715 24.999605739321026 1.0518641013603458 1.3336822884669635 0.6716677499796684 0.05937627690508087 95.5062522107529 462961.22788259125 0.014450632060623473 0.1189133363674992 1.7527392845095562e-05 4.756282679296715 0.28181818710661766 QFLLQQASGLS(ph)SPGNNDSK ddPTM_PC-9_Lapatinib_30min_R1 1 QFLLQQASGLSSPGNNDSK 19 0 A2A312;B7ZBM3;Q8IVH2-3;Q8IVH2-2;Q8IVH2 A2A312 FOXP4 Forkhead box protein P4 1 QFLLQQAS(0.061)GLS(0.607)S(0.32)PGNNDS(0.011)K 83.41799999999999 0.014094999999999998 0.0 13532.0 11738.0 11610.0 10864.0 11952.0 15038.0 13672.0 8603.9 17017.0 10342.0 True False 13339.031198535127 11710.821382180573 10655.470615896027 11662.974801241602 11249.0068585361 14394.85979529017 14379.869262390233 9003.66860408119 15100.366263045853 12129.600920151219 1.0997089917752076 0.9654745823273612 0.8784683590202724 0.9615299693715068 0.9274012337741331 1.1867546088326466 1.185518745179867 0.7422889395415444 1.2449186384985862 1.0 13.566244464221382 -6.712799888194916 24.999193551245988 1.0628918994859335 0.9612900679340297 0.1211609551006585 0.1405133716682409 268.5741792252739 138037.82361319728 0.0458887821753524 0.04588867539515681 1.93731442332551e-07 6.712799888194916 -0.10160183155190383 QFLSETEK ddPTM_PC-9_Lapatinib_30min_R1 1 QFLSETEK 8 0 P09936;D6RE83;D6R956;D6R974 P09936 UCHL1 Ubiquitin carboxyl-terminal hydrolase isozyme L1;Ubiquitin carboxyl-terminal hydrolase 0 122.28 0.015368000000000001 11261000.0 53534.0 48204.0 55575.0 50537.0 48722.0 51380.0 51242.0 50135.0 49485.0 49767.0 False True 52770.595343066765 48092.386599644946 51005.83802570384 54253.659566489936 45856.267751137544 49182.597172629896 53895.0600309684 52464.4551268158 43911.47819984859 58369.15963964081 0.9040835206273581 0.8239348809638077 0.8738491069702458 0.929491873815571 0.7856249436216781 0.8426127337839561 0.9233482264213742 0.8988386238678192 0.7523061574117056 1.0 15.832918676954966 -10.735089559066266 5.326349789095473 1.0000088394453945 0.8611756056489551 0.3626180239982485 0.055896930232399354 5.75922782060275e-06 8.517339763903165e-07 0.05312431828882266 0.012883719412316162 1.8403924414436198e-11 10.735089559066266 -0.13883323379643941 QFNDHLMPLIS(ph)S(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QFNDHLMPLISSSPK 15 0 F8W9B8;A0A0A0MSI8;O00471 F8W9B8 EXOC5 Exocyst complex component 5 2 QFNDHLMPLIS(0.985)S(0.507)S(0.507)PK 88.134 0.013719 0.0 26323.0 30295.0 26177.0 24476.0 35025.0 21730.0 27447.0 24202.0 19900.0 21501.0 True False 30778.96399705154 33302.48738732 26801.158956825322 23104.689072262638 28162.102679066258 20590.440546521277 24847.02146092816 23566.72314413865 20190.99985289874 25398.96109817766 1.2118198015295945 1.3111751799056617 1.0552068981572742 0.9096706350686276 1.108789551281562 0.8106804237752312 0.9782692041963441 0.9278616969034033 0.7949537689692125 1.0 14.632481866737443 -5.4561052964909305 3.2497095588985414 0.9346112862616209 1.2608329293154479 0.6828125630116058 0.08853551629424707 0.1345416463830365 2.754515033112867 0.02372757464368302 0.053451082204095474 3.4986033166196944e-06 5.4561052964909305 0.32622164305382695 QFS(ph)ALVPAFDPRPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QFSALVPAFDPRPGR 15 1 A0A087X2H1;Q9ULT8;H0YJP0;H0YJD4 A0A087X2H1 HECTD1 E3 ubiquitin-protein ligase HECTD1 1 QFS(1)ALVPAFDPRPGR 55.588 0.032948000000000005 1843600.0 5768.3 6787.6 14321.0 8393.5 11678.0 10059.0 8765.3 8604.0 9165.0 5846.2 True False 6744.759260881833 7461.428070314351 14662.466952694947 7923.239407094157 9389.779731224431 9531.488332142535 7934.987328723492 8378.15411669156 9299.020786523468 6906.0697815062595 0.9766422110219044 1.0804159683261938 2.1231275409292154 1.1472863231576045 1.3596415947561507 1.3801610226509549 1.1489874240733229 1.2131580452788633 1.3464996851646769 1.0 12.75364919645611 -7.255590392563263 23.084693861786764 1.1949244604942402 1.3596498013340141 0.06585536545699211 0.3027369900443395 549.8394762585463 2170108.9478263003 0.12094322422544498 0.09091217227790829 5.551490582738704e-08 7.255590392563263 0.16472534083977397 QFS(ph)APNLK ddPTM_PC-9_Lapatinib_30min_R1 1 QFSAPNLK 8 0 O60333-3 O60333-3 KIF1B Kinesin-like protein KIF1B 1 QFS(1)APNLK 88.134 0.011204 4285700.0 44979.0 45329.0 47724.0 35623.0 48285.0 40101.0 48634.0 41272.0 41619.0 40350.0 True False 44337.59121186161 45224.04348550547 43800.31693996739 38242.834254844405 45444.971231962445 38385.97370999674 51152.030552010416 43189.64779084357 36931.42995250072 47324.443737004585 0.936885628455735 0.955617011302412 0.9255326313686482 0.8080989703200894 0.9602853756615312 0.8111236113691801 1.0808797000610681 0.9126287470141381 0.780388041278186 1.0 15.530297927790498 QFS(ph)KSS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 QFSKSSR 7 1 B4DSZ9;E9PMS7;E9PCE7;E9PMP8;P53804-3;P53804-2;P53804 B4DSZ9 TTC3 E3 ubiquitin-protein ligase TTC3 2 QFS(1)KS(0.033)S(0.967)R 93.556 0.044534 545740.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 QFS(ph)T(ph)LT(ph)T(ph)HKK ddPTM_PC-9_AZD4547_30min_R2 1 QFSTLTTHKK 10 1 M0QY39;A0A087X1I5;Q68DY1-2;Q68DY1 M0QY39 ZNF626 Zinc finger protein 626 4 QFS(1)T(1)LT(1)T(1)HKK 52.58 0.039576 0.0 2746.4 3315.9 3398.8 4166.6 4939.5 2881.7 3147.1 5568.4 3858.0 3567.1 True False 3619.6980713312496 4387.699829041329 3353.729691263531 3206.0547433282914 4253.735686976331 2701.5068434522823 3427.1858032594646 4707.93172910237 4061.926003736897 3442.21691474074 1.051560131446242 1.2746726710486231 0.9742935365001908 0.9313924202739455 1.2357546872657537 0.7848159806209521 0.9956333049736329 1.367703385844573 1.1800319690320367 1.0 11.749122297775353 -7.729962508975345 24.999502166342353 1.2054011245352798 1.036357554381453 0.15153334710836364 0.15676766907572784 313.19356824216095 248744.12626271375 0.0738699599450713 0.04264387053023581 1.862247890646701e-08 7.729962508975345 -0.16904357015382687 QFSCLS(ph)LPSSWNYRHAPPCPASPPWPPK ddPTM_PC-9_AZD4547_30min_R2 1 QFSCLSLPSSWNYRHAPPCPASPPWPPK 28 1 H0Y353 H0Y353 EDRF1 1 QFS(0.034)CLS(0.245)LPS(0.245)S(0.245)WNY(0.231)RHAPPCPASPPWPPK 40.141999999999996 0.035098000000000004 4841800.0 11142.0 8402.3 11023.0 20358.0 13977.0 14670.0 10255.0 13766.0 11218.0 12578.0 True False 14684.924232002915 11118.179159068117 10876.827817699748 15664.777627964628 12036.534810581674 13752.682580922727 11167.675133432615 11638.781011210265 11810.9605779991 12137.648048445235 1.2098657147901049 0.9160077071514933 0.8961231841858365 1.2905941550983757 0.9916694537969806 1.1330599244624142 0.9200855955666907 0.9588992006322945 0.9730847797578064 1.0 13.567201272512568 -7.271693731583802 24.733476572965095 0.9595923263516264 1.0639252247651119 0.17286611996688328 0.11665811029557552 1226.2534929657759 2957708.632244425 0.04862871159001605 0.033218944412647396 5.349414719981784e-08 7.271693731583802 0.10433289841348548 QFSIQAEDERES(ph)TDDESNPLGR ddPTM_PC-9_Lapatinib_30min_R1 1 QFSIQAEDERESTDDESNPLGR 22 1 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 QFSIQAEDERES(0.765)T(0.234)DDES(0.001)NPLGR 80.752 0.00022457 5175000.0 10161.0 9647.3 8897.6 6594.2 9020.0 10745.0 7931.4 5950.8 10554.0 5797.5 True False 10016.102276700813 9624.962269578344 8166.073673729241 7079.159465606342 8489.461334002312 10285.46139781838 8342.049083361748 6227.295892463461 9365.297381453007 6799.5901503168325 1.4730450005481734 1.415520944174828 1.2009655719247632 1.0411156127221113 1.2485254473178413 1.5126590236235224 1.2268458684929773 0.9158340068736783 1.3773326295286523 1.0 12.73123207427136 -1.5228787452803376 0.092395053952874 0.8930678532783295 2.289279479253336 0.2458255048982555 0.1698034215668543 242.00360602051583 1.6085334223157248 3.0767598589195844 42.79816335953209 0.029999999999999995 1.5228787452803376 1.3962116259750066 QFSTAS(ph)DHEQPGVSG ddPTM_PC-9_AZD4547_30min_R2 2 QFSTASDHEQPGVSG 15 0 Q66K14;Q66K14-2;G3V133 Q66K14 TBC1D9B TBC1 domain family member 9B 1 QFS(0.02)T(0.058)AS(0.895)DHEQPGVS(0.027)G;QFS(0.09)T(0.03)AS(0.818)DHEQPGVS(0.062)G 95.073 0.0029093000000000005 17237200.0 36653.0 33048.0 70576.0 115537.0 84001.0 80314.0 47877.0 98211.0 63171.0 74094.0 True False 48307.89157023899 43730.11971113656 69640.11612646081 88901.72967885586 72338.91111280464 75291.95288372364 52137.96024996134 83034.7466142649 66510.09009384744 71499.99161245825 0.6756349263937782 0.6116101376369528 0.9739877523891433 1.2433809805281921 1.011733141241379 1.0530344295957186 0.7292023267996685 1.1613252637053013 0.9302111593850682 1.0 16.125655452200398 -5.300134549053697 5.589554838814465 1.0198745865727825 0.6423975135980113 0.5664789831519954 0.12935174372638106 0.12342106159082579 10.656300744618536 0.034125794230073246 0.07557375183845202 5.010319845371491e-06 5.300134549053697 -0.3774770729747712 QFSTAS(ph)DHEQPGVSG ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QFSTASDHEQPGVSG 15 0 Q66K14;Q66K14-2;G3V133 Q66K14 TBC1D9B TBC1 domain family member 9B 1 QFS(0.05)T(0.071)AS(0.653)DHEQPGVS(0.226)G 64.476 0.035868000000000004 5996200.0 12939.0 14207.0 26847.0 20774.0 27095.0 18742.0 26771.0 16008.0 22226.0 17434.0 True False 15129.317143101092 15617.377069207949 27487.13429781449 19610.10013021672 21785.92925308495 17759.13652659464 24235.057074744367 15587.806961878008 22551.01320253909 20594.646192531935 0.7346237950223836 0.7583221835037471 1.3346737807897822 0.9521940773776326 1.057844308147668 0.8623181170761987 1.1767649149288384 0.7568863682412027 1.094993960649665 1.0 14.329981721066902 -5.046730504615271 24.999725639861072 1.020201075396403 0.7405475441396931 0.357238876504143 0.1515737762640326 366.28408341401996 195953.26620468823 0.03650805533711931 0.09659798135880396 8.979858542449405e-06 5.046730504615271 -0.2796535312567099 QFSTAS(ph)DHEQPGVSG ddPTM_PC-9_Lapatinib_30min_R1 1 QFSTASDHEQPGVSG 15 0 Q66K14;Q66K14-2;G3V133 Q66K14 TBC1D9B TBC1 domain family member 9B 1 QFS(0.029)T(0.029)AS(0.742)DHEQPGVS(0.2)G 80.719 0.0095587 7361500.0 24557.0 19108.0 31354.0 19043.0 29960.0 33021.0 20450.0 26353.0 29928.0 23654.0 True False 24206.812676797737 19063.756599992023 28776.195149940024 20443.48574558576 28197.811703626303 31608.768805710635 21508.800937381504 27577.456586356373 26557.19348418853 27742.562383026194 0.8725514371234957 0.6871663956915477 1.0372580136125509 0.7368996945319569 1.0164097791081708 1.139360105577339 0.7752997232346963 0.9940486464663827 0.957272551739384 1.0 14.759813424837455 -5.719101954147586 1.1249442688594784 0.9689835131124469 0.7971210060501503 0.18934473264401108 0.12583721841813242 0.9662815210734742 2.3298332515518605 0.04531254339827632 0.13416402124846252 1.909404957666406e-06 5.719101954147586 -0.17186250706229655 QFSTASDHEQPGVS(ph)G ddPTM_PC-9_Lapatinib_30min_R1 1 QFSTASDHEQPGVSG 15 0 Q66K14;Q66K14-2;G3V133 Q66K14 TBC1D9B TBC1 domain family member 9B 1 QFS(0.025)T(0.005)AS(0.126)DHEQPGVS(0.843)G 93.71600000000001 0.0031892 7403500.0 31766.0 17569.0 31670.0 21003.0 31179.0 36593.0 22699.0 26777.0 38526.0 24709.0 True False 31313.011014829062 17528.320059936148 29066.2148497353 22547.630683954096 29345.112520272512 35028.002692449336 23874.24315294001 28021.157174244487 34186.796183234655 28979.917727327043 1.0805072433073886 0.6048436791595015 1.0029778249621075 0.7780432952262136 1.0126016504388176 1.2086991765135056 0.8238202529618446 0.9669163811262832 1.1796719543823173 1.0 14.822765878704272 -6.345703752228408 7.25500781400835 1.0296716167716575 0.857960829070144 0.21218615806015528 0.15585784494040753 0.4188566620259514 31.47310789637445 0.04681124696123551 0.05312580610556008 4.5112432761941566e-07 6.345703752228408 -0.1717107877015135 QFTPCQLLADHANS(ph)PNKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QFTPCQLLADHANSPNKK 18 1 A0A2R8Y4F5;H0YFD6;P40939 A0A2R8Y4F5 HADHA Trifunctional enzyme subunit alpha, mitochondrial;Long-chain enoyl-CoA hydratase;Long chain 3-hydroxyacyl-CoA dehydrogenase 1 QFTPCQLLADHANS(1)PNKK;QFTPCQLLADHANS(1)PNKK 59.15 0.010876 14766900.0 75756.0 73535.0 72406.0 83124.0 112376.0 76303.0 81269.0 71812.0 71940.0 70787.0 True False 88579.99455079732 80835.06882411533 74132.43364128412 78466.831771644 90356.72949786585 72301.5363562453 73570.61198339233 69927.0110911035 72991.98640289111 83620.12275041627 1.0593143329289882 0.9666939746714606 0.8865382063902206 0.9383725972975014 1.0805620289216336 0.8646427914492074 0.8798194688493935 0.8362462143211264 0.8728997758201419 1.0 16.351562540741675 -6.814365902434757 24.999893942589097 0.8798054634711209 0.9770034789098357 0.33187919273530064 0.06625997658515674 115.29038593807888 54456.57904971568 0.02350145281680589 0.02072635412747054 1.533324579524882e-07 6.814365902434757 0.09719801543871487 QGAIYHGLATLLNQPS(ph)PMMQR ddPTM_PC-9_AZD4547_30min_R2 2 QGAIYHGLATLLNQPSPMMQR 21 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 QGAIYHGLAT(0.023)LLNQPS(0.977)PMMQR;QGAIYHGLAT(0.001)LLNQPS(0.999)PMMQR 94.27600000000001 0.00026559 15637500.0 87607.0 84728.0 118234.0 164465.0 140712.0 127050.0 125766.0 148678.0 105283.0 129957.0 True False 115464.2036611987 112114.66905365471 116666.13990727668 126550.13520892052 121176.56766592029 119105.54341555758 136958.93035897496 125703.23138055485 110848.04444049552 125407.24498583224 0.9207139800754187 0.89400472091003 0.9302982448937215 1.009113430593403 0.9662644903778095 0.9497500995976222 1.0921133812838943 1.0023602017152682 0.8839046296967809 1.0 16.936261171884595 -5.620075651011348 4.758304903805025 0.9881822406472498 0.9083104978471145 0.3053420366208627 0.04982732169249794 0.2511687266684801 9.596949614351994 0.014096101355368887 0.02517193852575981 2.3984150957702778e-06 5.620075651011348 -0.07987174280013531 QGAIYHGLATLLNQPS(ph)PMMQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QGAIYHGLATLLNQPSPMMQR 21 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 QGAIYHGLAT(0.003)LLNQPS(0.997)PMMQR 52.318000000000005 0.015574000000000001 19307000.0 27495.0 26632.0 37394.0 46819.0 53229.0 38869.0 46878.0 44580.0 41892.0 32907.0 True False 32149.360448996395 29275.84895524363 38285.614777534734 44195.88321924599 42799.1595575737 36830.641215036114 42437.37647267062 43409.82223641441 42504.59124812231 38872.77860833131 0.827040453498893 0.7531195351435247 0.984895244131822 1.1369365607884232 1.1010059247064186 0.9474661326922094 1.091699075598762 1.1167151870926642 1.0934281718418921 1.0 15.246472614090138 -5.40906487515171 3.8576943226929528 1.0713200394508582 0.7915740366574788 0.7896420754481519 0.05678593576068843 0.09764893050881279 2.528420232527035 0.01564196173572044 0.03496392849230831 3.898837412757585e-06 5.40906487515171 -0.27974600279337936 QGAIYHGLATLLNQPS(ph)PMMQR ddPTM_PC-9_Lapatinib_30min_R1 1 QGAIYHGLATLLNQPSPMMQR 21 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 QGAIYHGLATLLNQPS(1)PMMQR 75.564 0.00072729 4388400.0 33829.0 26070.0 24828.0 24805.0 28454.0 27722.0 19680.0 22632.0 30117.0 19552.0 True False 33346.59225652118 26009.636516736016 22786.737678851554 26629.242447054283 26780.39166271637 26536.39468313832 20698.934105020442 23683.565342178015 26724.906313930303 22931.537148597632 1.454180417144887 1.1342299623523766 0.9936855750747204 1.1612497790486227 1.1678411041169177 1.1572008675729415 0.9026404977080342 1.032794495576428 1.1654214953298345 1.0 14.485045444556723 -4.773597931014523 3.8542387801286044 1.076445894243956 1.4942467659940502 0.6333707642895107 0.08657305618525618 0.16868262477562213 4.527330317609095 0.02277073234314063 0.20225945995143035 1.684232598773153e-05 4.773597931014523 0.41780087175009406 QGDTGDWIGTFLGHK ddPTM_PC-9_AZD4547_30min_R2 1 QGDTGDWIGTFLGHK 15 0 Q9Y3F4-2;Q9Y3F4 Q9Y3F4-2 STRAP Serine-threonine kinase receptor-associated protein 0 137.19 3.2941e-05 2266200.0 11695.0 13323.0 16130.0 22104.0 21465.0 16451.0 13607.0 17639.0 14959.0 16496.0 False True 15413.76672888835 17629.399204535002 15916.10566084522 17008.26430339572 18484.95526287012 15422.316369376944 14817.996639748182 14913.297853896393 15749.702200596226 15918.480060991635 0.9682938741532183 1.107480056951919 0.9998508400213263 1.0684603202208112 1.161226146720355 0.9688309631501475 0.9308675566368804 0.9368543853908232 0.9893973633318799 1.0 13.958414969629874 -6.963182451512567 24.954352481929394 0.9577078712279241 1.061089189580419 0.4443150180063783 0.05342572486624575 144.84548011175767 98173.55616137724 0.018468631681374796 0.01628776838454082 1.0884727188476175e-07 6.963182451512567 0.10338131835249498 QGEAEFNR ddPTM_PC-9_Lapatinib_30min_R1 1 QGEAEFNR 8 0 O43707;O43707-2;F5GXS2;O43707-3 O43707 ACTN4 Alpha-actinin-4 0 98.58200000000001 0.025166 18933000.0 57360.0 76637.0 76215.0 69499.0 76607.0 63538.0 83355.0 83366.0 74007.0 86337.0 False True 56542.0358814643 76459.5517350631 69948.89689840801 74610.18830186765 72101.12687515687 60820.6278543122 87670.71404085265 87239.48870254563 65671.5523317408 101260.2354131787 0.5583834132989338 0.755079735130777 0.6907834710534791 0.7368162635355414 0.7120379147940746 0.6006368403761048 0.8657960717069653 0.8615374865224902 0.6485423627920368 1.0 16.627708217826708 -14.522878745265164 0.122202741328214 1.9162215376083354 0.5901274317255947 0.5104828937400214 0.08913977184644611 127.9472578972934 1.0040105349049449 28.866499338134155 0.8114854010192724 3.000000000104817e-15 14.522878745265164 -1.3260941058827407 QGEVPES(ph)PEAR ddPTM_PC-9_AZD4547_30min_R2 1 QGEVPESPEAR 11 0 H7BYP4;U5Y3L1;Q9H930-3;Q9H930-1;Q9H930-2;Q9H930 H7BYP4 SP140L Nuclear body protein SP140-like protein 1 QGEVPES(1)PEAR 85.271 0.011554 9255700.0 23256.0 18031.0 22841.0 39238.0 31226.0 21374.0 18562.0 31366.0 20442.0 20226.0 True False 30650.924245149832 23859.168134577103 22538.113415955722 30192.285321056865 26890.808899994503 20037.480401134428 20213.98204064128 26519.105418975825 21522.522386829878 19517.89389631526 1.5704012127525886 1.2224253426790799 1.1547410563703617 1.5469028308816044 1.3777515669900817 1.0266210333747772 1.0356641012613268 1.3587073256906221 1.1027072132456395 1.0 14.252509764967131 -6.749124823225842 24.996205524321514 1.1228419047444111 1.363374234059056 0.44048709918751516 0.15103990136547116 253.0460893708093 513634.35854523035 0.05154519648313437 0.05119300747897755 1.7818665567079922e-07 6.749124823225842 0.24053232931464485 QGEVPES(ph)PEAR ddPTM_PC-9_Lapatinib_30min_R1 1 QGEVPESPEAR 11 0 H7BYP4;U5Y3L1;Q9H930-3;Q9H930-1;Q9H930-2;Q9H930 H7BYP4 SP140L Nuclear body protein SP140-like protein 1 QGEVPES(1)PEAR 82.515 0.013859 11365000.0 19270.0 18174.0 22162.0 19506.0 19847.0 21072.0 18322.0 18819.0 22364.0 16675.0 True False 18995.20626631479 18131.91921960723 20339.925907793946 20940.536310108495 18679.638480703317 20170.79968123117 19270.623509765475 19693.399442137154 19845.13081663966 19557.25153195916 0.9712615412893826 0.9271200091678145 1.0400196507446762 1.0707300192917633 0.9551259516286476 1.0313719005080746 0.9853441562724039 1.0069615052992242 1.0147198231924393 1.0 14.255416015697303 -5.258704078545722 24.995427022544792 1.0129411628150682 0.9491907735420745 0.40209423217555396 0.031140511927601325 222.5458035048318 2033617.3175440691 0.008020835418524145 0.019261729384700173 5.5118313603301545e-06 5.258704078545722 -0.0637503892729937 QGGLGPMNIPLVSDPK ddPTM_PC-9_Lapatinib_30min_R1 1 QGGLGPMNIPLVSDPK 16 0 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 89.663 0.017049 56865000.0 24341.0 21093.0 116520.0 19090.0 25286.0 27992.0 22073.0 17861.0 65663.0 25680.0 False True 23993.89287640729 21044.160454450055 106940.17538020712 20493.942282373155 23798.727194188727 26794.84741253906 23215.831935981514 18690.887264786215 58267.34147795605 30118.753783550896 0.7966429503969502 0.6987062149278948 3.5506175371243813 0.6804379234829347 0.7901630779685912 0.8896399766438159 0.7708098450162518 0.620573062189382 1.934586732794312 1.0 14.87837445674766 QGGS(ph)PDEPDSK ddPTM_PC-9_AZD4547_30min_R2 2 QGGSPDEPDSK 11 0 V9GZ50;Q9ULX6;Q9ULX6-2 V9GZ50 AKAP8L A-kinase anchor protein 8-like 1 QGGS(0.956)PDEPDS(0.044)K;QGGS(0.993)PDEPDS(0.007)K 89.992 0.0089802 9529000.0 28810.0 33022.0 38066.0 47593.0 35859.0 38620.0 30932.0 47959.0 33231.0 34922.0 True False 37970.980714773286 43695.7157195943 37561.21996811744 36621.16915452011 30880.59682139574 36205.08529483541 33684.88807677599 40548.03853818343 34987.52281756891 33699.39140942954 1.1267556809393449 1.2966321910302407 1.1145963887528043 1.0867012020956859 0.9163547331230123 1.0743542770539394 0.9995696262737407 1.2032276205094181 1.038224174213987 1.0 15.040434916994386 -5.562508680481629 3.0954859574361397 1.0477565008684537 1.2121191263527868 0.4041693655588645 0.0797153663876439 0.2404530726058382 4.687826946541762 0.02227557949569982 0.04546195952195261 2.7383649005185765e-06 5.562508680481629 0.1643626254843331 QGGS(ph)PDEPDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QGGSPDEPDSK 11 0 V9GZ50;Q9ULX6;Q9ULX6-2 V9GZ50 AKAP8L A-kinase anchor protein 8-like 1 QGGS(0.739)PDEPDS(0.261)K 82.20200000000001 0.014207 2850000.0 17248.0 21075.0 16898.0 18480.0 20482.0 17443.0 19604.0 22605.0 16049.0 13294.0 True False 20167.74573647172 23167.1867201772 17300.91240602187 17444.625512968367 16468.69913126724 16528.25837335344 17746.967199330928 22011.6427019773 16283.686263274969 15704.096964753908 1.284234667025807 1.4752320220750905 1.101681455791558 1.1108327688068202 1.0486880696310903 1.052480662240514 1.1300851770822617 1.4016496937951908 1.0369068848608032 1.0 13.93885336539649 -5.27202863648167 24.864018897958367 1.121096794673572 1.3797333449905667 0.4713801058406041 0.11367348268971436 517.6720777348801 1215517.4687428554 0.0302809369101998 0.06411689753640087 5.345291124886232e-06 5.27202863648167 0.25863655031699473 QGGS(ph)PDEPDSK ddPTM_PC-9_Lapatinib_30min_R1 2 QGGSPDEPDSK 11 0 V9GZ50;Q9ULX6;Q9ULX6-2 V9GZ50 AKAP8L A-kinase anchor protein 8-like 1 QGGS(0.937)PDEPDS(0.063)K;QGGS(0.993)PDEPDS(0.007)K 118.08 0.0010989 5262100.0 41727.0 44693.0 42862.0 41787.0 45628.0 47064.0 47840.0 44685.0 43512.0 38556.0 True False 41131.96532820535 44589.516104429735 39338.051812104684 44860.155377345574 42944.25074809946 45051.18243154253 50316.9211170822 46761.22823061265 38611.220358327024 45220.35322735936 0.909589651398821 0.986049708197592 0.8699191626018581 0.9920346077748934 0.9496664153016212 0.9962589678376401 1.112705176452255 1.0340748113024696 0.8538460583047004 1.0 15.464684640930562 -6.414652084577379 1.710541834193514 1.0067124018941276 0.9334431301177295 0.1504664816338135 0.06796387735557702 0.6741021519658175 3.938093156531146 0.026079563567165565 0.030946523411188535 3.8490000383578146e-07 6.414652084577379 -0.07326927177639808 QGGSPDEPDS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 QGGSPDEPDSK 11 0 V9GZ50;Q9ULX6;Q9ULX6-2 V9GZ50 AKAP8L A-kinase anchor protein 8-like 1 QGGS(0.446)PDEPDS(0.554)K 96.756 0.0056729 2430600.0 20429.0 20100.0 18638.0 26354.0 29297.0 21182.0 22906.0 26424.0 20144.0 20322.0 True False 26924.997050402733 26596.931923076903 18390.847942147142 20278.49246524115 25229.61725303079 19857.486191486372 24944.58962519819 22340.77796311347 21208.770715208935 19610.532965535393 1.3729865015765852 1.3562574749916172 0.9378045958500062 1.0340612619187692 1.2865339915733385 1.012592887015615 1.2719995764030052 1.1392233960380556 1.0814989451068144 1.0 14.259341124477078 -5.178922533292136 9.419744539647445 1.1085008863846562 1.366448287584703 0.49719552789199417 0.10764201432946727 0.37611830051626965 40.636176373073745 0.027295075657670666 0.07256274422584759 6.623346362364963e-06 5.178922533292136 0.2579474012000469 QGGSPDEPDS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 2 QGGSPDEPDSK 11 0 V9GZ50;Q9ULX6;Q9ULX6-2 V9GZ50 AKAP8L A-kinase anchor protein 8-like 1 QGGS(0.085)PDEPDS(0.915)K;QGGS(0.01)PDEPDS(0.99)K 130.15 0.00022343 10683000.0 46176.0 45273.0 47056.0 45017.0 48936.0 44495.0 45737.0 45051.0 45968.0 37582.0 True False 45517.52177235869 45168.17315006485 43187.23732141286 48327.700352309716 46057.6806918777 42592.052572911016 48105.038067140275 47144.23392676132 40790.59977550048 44077.99862513279 1.0326585414975058 1.024732849923691 0.9797912488882373 1.096413218833257 1.0449131568695162 0.9662882594815795 1.0913616672176063 1.06956385038499 0.9254185999325779 1.0 15.42777109894069 -8.259069965790404 24.99826687238168 0.9627092994512175 1.0373556261116699 0.32624873076703687 0.04338866045716752 236.4957846647391 2495196.6456949976 0.03271392039022522 0.011018546099614052 5.5071896722886845e-09 8.259069965790404 0.07464632666045234 QGGYSQSNYNS(ph)PGSGQNYSGPPSSYQSSQGGYGR ddPTM_PC-9_AZD4547_30min_R2 1 QGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGR 34 0 Q12906-7;Q12906;K7ELV3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 QGGYSQS(0.003)NY(0.008)NS(0.812)PGS(0.142)GQNY(0.03)S(0.005)GPPSSYQSSQGGYGR 127.95 5.248200000000001e-18 0.0 2774.5 2644.4 2731.8 5300.9 5062.9 3405.1 2595.2 4633.9 2493.3 3715.0 True False 3656.7332868149397 3499.150585939531 2695.574547073589 4078.859403088595 4360.003727015381 3192.1785587116533 2826.167772431433 3917.837231428682 2625.0907478271674 3584.938980757996 1.02002664660188 0.9760697754469657 0.7519164375019961 1.1377765214364026 1.2162002618224497 0.8904415321559259 0.7883447354615423 1.0928602278748685 0.7322553499284724 1.0 11.807732847687724 QGHRPLSQS(ph)IVEAGSVGQTDLNK ddPTM_PC-9_Lapatinib_30min_R1 1 QGHRPLSQSIVEAGSVGQTDLNK 23 1 A0A590UJ23;K7EKN5;A0A590UJ36;A6NDB9 A0A590UJ23 PALM3 Paralemmin-3 1 QGHRPLS(0.283)QS(0.673)IVEAGS(0.013)VGQT(0.031)DLNK 51.044 0.012934999999999999 4758100.0 19679.0 22773.0 11262.0 7772.8 9872.1 10949.0 8384.0 4439.8 17430.0 4661.2 True False 19398.373851313394 22720.27051766895 10336.08183257717 8344.437641300688 9291.442487295364 10480.736793365608 8818.082496772939 4646.089316286763 15466.849853963036 5466.882209341408 3.5483431156001264 4.15598318157399 1.8906721302528944 1.526361337554031 1.699587101294926 1.9171323602796657 1.61300027311824 0.8498608783536374 2.829190251718688 1.0 12.4165025759066 -5.308607331262302 5.57783236385744 1.6523930928611512 3.8549164046834297 0.7348229083718214 0.5259855830868689 0.08356854676544989 6.405435514888576 0.12961112040794115 0.28418787748940866 4.913519327882088e-06 5.308607331262302 2.2025233118222785 QGIAVMTPTVPGS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 QGIAVMTPTVPGSPK 15 0 Q9UPX8;Q9UPX8-3;H7C1X5;E7EUA2;A6NHU9;A0A0A0MSQ6;A0A590UJ45;Q9UPX8-4;E7EX50;H0Y7S5;Q9UPX8-2 Q9UPX8 SHANK2 SH3 and multiple ankyrin repeat domains protein 2 1 QGIAVMT(0.001)PT(0.002)VPGS(0.997)PK;QGIAVMTPTVPGS(1)PK;QGIAVMT(0.002)PT(0.001)VPGS(0.997)PK;QGIAVMT(0.03)PT(0.008)VPGS(0.963)PK 147.09 0.00012068 28115400.0 129349.0 136638.0 137685.0 153544.0 172234.0 178928.0 207736.0 185199.0 180454.0 184115.0 True False 170479.2913736621 180803.56139827767 135859.20693821926 118146.80303115248 148322.2820752466 167739.603874529 226224.10156204365 156580.74999964598 189992.43003585763 177669.1898902445 0.9595321027746905 1.0176416153524954 0.7646751078346592 0.6649819425874453 0.8348227521433118 0.9441119418518792 1.2732883045270484 0.8813050259100863 1.0693605917448368 1.0 17.438833995722398 -7.004801925095698 11.692978480298196 1.0550399951386595 0.8475049510100495 0.3704087402148888 0.12762593250949164 0.2856188257662508 657.0624524089529 0.0491656148836857 0.04135376468911978 9.890040610563534e-08 7.004801925095698 -0.20753504412861 QGIAVMTPTVPGS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QGIAVMTPTVPGSPK 15 0 Q9UPX8;Q9UPX8-3;H7C1X5;E7EUA2;A6NHU9;A0A0A0MSQ6;A0A590UJ45;Q9UPX8-4;E7EX50;H0Y7S5;Q9UPX8-2 Q9UPX8 SHANK2 SH3 and multiple ankyrin repeat domains protein 2 1 QGIAVMT(0.006)PT(0.036)VPGS(0.959)PK 119.68 8.2237e-05 15222000.0 49446.0 58950.0 43985.0 72138.0 79788.0 55361.0 68362.0 59764.0 63027.0 55685.0 True False 57816.23119698401 64802.166413022394 45033.76921404142 68096.34173455168 64154.11416295038 52457.77170252942 61886.256461980185 58195.258325192226 63948.65063963065 65780.24969778255 0.8789299442098802 0.9851310493764647 0.684609277419017 1.0352095354975097 0.9752792739111937 0.7974699388272126 0.9408030031249086 0.8846919644203477 0.9721557904300013 1.0 16.005366864114812 -8.391944886131785 3.7002110529891064 0.9990528536634042 0.8988048822272755 0.12344525877358248 0.09514334613388985 0.4882203602669987 11.238002128751898 0.08831144959545666 0.023416532584065015 4.0555999951959814e-09 8.391944886131785 -0.10024797143612874 QGIAVMTPTVPGS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 QGIAVMTPTVPGSPK 15 0 Q9UPX8;Q9UPX8-3;H7C1X5;E7EUA2;A6NHU9;A0A0A0MSQ6;A0A590UJ45;Q9UPX8-4;E7EX50;H0Y7S5;Q9UPX8-2 Q9UPX8 SHANK2 SH3 and multiple ankyrin repeat domains protein 2 1 QGIAVMT(0.012)PT(0.283)VPGS(0.706)PK;QGIAVMT(0.004)PT(0.033)VPGS(0.963)PK;QGIAVMTPT(0.002)VPGS(0.997)PK;QGIAVMT(0.014)PT(0.002)VPGS(0.984)PK 170.5 8.9041e-21 10638600.0 190468.0 174368.0 108234.0 156595.0 141071.0 110415.0 107192.0 114809.0 136924.0 106850.0 True False 187751.89139244627 173964.26160913808 99335.41831532204 168111.51868560637 132773.48113625703 105692.80783993629 112741.87726551598 120143.4452708606 121502.17724635899 125318.88013132435 1.4981931788386318 1.388172807056983 0.7926612351724363 1.3414700044353947 1.059485059211516 0.8433909378154235 0.8996399995545072 0.9587018743301863 0.9695440712447657 1.0 16.935244257172528 -1.5228787452807229 0.5311589782965296 0.9449276348251705 24.49348863862946 0.5610319288194239 0.154360114218307 90.12495793076812 0.8751057022904403 0.07976187370825744 2402.669258007486 0.029999999999973385 1.5228787452807229 23.54856100380429 QGLAET(ph)ASPVAVSLR ddPTM_PC-9_AZD4547_30min_R2 1 QGLAETASPVAVSLR 15 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 QGLAET(0.632)AS(0.35)PVAVS(0.018)LR 119.08 0.00025155 4572200.0 12235.0 16560.0 17496.0 18994.0 22337.0 22753.0 19450.0 26219.0 15146.0 14764.0 True False 16125.475496190595 21912.696151549928 17263.99160831667 14615.226754374686 19235.89311468575 21330.25131313801 21181.012320357324 22167.456002682116 15946.58663882816 14247.116853811862 1.1318413165030068 1.5380442496817954 1.2117533523070414 1.0258375013232475 1.3501604087383565 1.4971626562767353 1.4866876251309946 1.555925751865448 1.1192851720424823 1.0 13.798382374507375 -6.500758297833471 24.582996933874735 1.3815066941240894 1.2405140459624553 0.03517696378900004 0.20406273604195416 1571.6807784163857 1746648.9787711592 0.06303543593670335 0.07086603775584611 3.156760997735156e-07 6.500758297833471 -0.14099264816163415 QGLAETAS(ph)PVAVSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QGLAETASPVAVSLR 15 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 QGLAET(0.084)AS(0.831)PVAVS(0.084)LR;QGLAET(0.404)AS(0.581)PVAVS(0.015)LR 121.26 6.8516e-05 7210400.0 32679.0 33961.0 38542.0 32465.0 39531.0 29700.0 34127.0 33267.0 26229.0 26415.0 True False 38210.90926032927 37332.42363957005 39460.987451348985 30646.091302950128 31785.184325657894 28142.47971613812 30894.243501916284 32393.776499300067 26612.54950460709 31203.83039897507 1.2245582920994325 1.196405158028172 1.264619982444371 0.9821259413061268 1.018630851381051 0.9018918304677908 0.9900785610900847 1.0381346163310796 0.8528616251382142 1.0 14.929435516278525 -5.768468625037368 24.90145909900537 0.9708293797618486 1.2253155567538017 0.8286510214857401 0.05405002193351163 55.57195144895093 196867.15625382986 0.014674830377268754 0.022302806444536298 1.7042424353429084e-06 5.768468625037368 0.2544861769919531 QGLAETAS(ph)PVAVSLR ddPTM_PC-9_Lapatinib_30min_R1 1 QGLAETASPVAVSLR 15 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 QGLAET(0.111)AS(0.471)PVAVS(0.418)LR 66.02199999999999 0.032718000000000004 5269100.0 13737.0 14533.0 16263.0 11053.0 11113.0 13703.0 12424.0 17344.0 15624.0 14789.0 True False 13541.107860942735 14499.34973140486 14925.91891699543 11865.874491727114 10459.355188998637 13116.95463325317 13067.253928901126 18149.865557384917 13864.26059198614 17345.258944896173 0.7806806403963887 0.8359258156633793 0.8605186561015492 0.6840990111144254 0.6030094576406594 0.756227086313567 0.7533617094108678 1.0463876967789805 0.7993112490295619 1.0 14.082253758122953 -7.739598781102393 24.8572678194065 0.9421370684122847 0.7523555985202669 0.49619144754219413 0.09004460406714246 190.1775892818333 216445.70835567178 0.04462306424868231 0.025734292809219905 1.8213827490185856e-08 7.739598781102393 -0.18978146989201783 QGLGPASTTSPSPGPRS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 QGLGPASTTSPSPGPRSPK 19 1 E9PCM6;E7EQN5;P98171;P98171-2 E9PCM6 ARHGAP4 Rho GTPase-activating protein 4 1 QGLGPASTTSPSPGPRS(0.999)PK;QGLGPASTT(0.001)S(0.002)PS(0.011)PGPRS(0.986)PK 116.04 3.3091e-05 13547300.0 20463.5 21435.0 29607.0 52777.0 44272.0 31033.0 43452.0 40109.0 41094.0 46867.0 True False 26970.46733275818 28363.44456572904 29214.391835129863 40610.07804652172 38125.59699034642 29092.501604210964 47319.143822322214 33911.0756631289 43266.144944936255 45226.20059520458 0.5963460776675967 0.6271463044086987 0.6459616649342753 0.8979325592702492 0.8429980075396595 0.643266540663062 1.0462772286765905 0.7498104023074746 0.9566610587563671 1.0 15.46487118134029 -3.7510030620704704 0.22742724789101262 0.986949031561802 8.053450957895469e-17 0.5428345431617958 0.10877162980542618 15.055496847599203 0.4646535228710044 0.17255091350349996 4.504009728031603 0.00017741769716958457 3.7510030620704704 -0.9869490315618019 QGLGPASTTSPSPGPRS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QGLGPASTTSPSPGPRSPK 19 1 E9PCM6;E7EQN5;P98171;P98171-2 E9PCM6 ARHGAP4 Rho GTPase-activating protein 4 1 QGLGPAS(0.005)T(0.005)T(0.02)S(0.055)PS(0.016)PGPRS(0.9)PK;QGLGPAS(0.001)T(0.004)T(0.009)S(0.099)PS(0.358)PGPRS(0.529)PK 66.041 0.0047902000000000005 10438600.0 24819.0 23774.0 23200.0 35811.0 41911.0 39789.0 35517.0 43357.0 33477.0 28322.0 True False 29020.366502405588 26134.12560310763 23753.17598648995 33804.625770828476 33698.84041063086 37702.394795468674 32152.572639187758 42218.924690538784 33966.53779273824 33456.554403171365 0.8674045196852289 0.7811361949642478 0.7099707788270742 1.0104036824432858 1.0072418099168194 1.1269060866559182 0.9610246247037322 1.2619029497710867 1.0152431533570754 1.0 15.030001253454685 -5.879594018684698 4.798347206757617 1.0681360467672825 0.7868318175102949 0.665036469515683 0.08768062604902731 0.1190344846518123 4.472560374498092 0.02461570291909211 0.0374700652524351 1.3194896297243432e-06 5.879594018684698 -0.2813042292569876 QGLGPASTTSPSPGPRS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 QGLGPASTTSPSPGPRSPK 19 1 E9PCM6;E7EQN5;P98171;P98171-2 E9PCM6 ARHGAP4 Rho GTPase-activating protein 4 1 QGLGPAST(0.001)T(0.002)S(0.002)PS(0.01)PGPRS(0.984)PK;QGLGPASTTSPS(0.01)PGPRS(0.99)PK 84.70700000000001 0.00063145 14957500.0 49946.0 27900.0 28576.0 34607.0 27349.0 25473.0 23396.3 21029.5 32205.0 21575.2 True False 49233.76088102538 27835.39926417089 26226.59158654993 37152.11422556772 25740.38559020278 24383.579170463257 24607.645935024888 22006.60734196415 28577.733766315516 25304.44457285307 1.9456566509206839 1.10002016381079 1.0364420966064654 1.4682050862094393 1.0172278437526896 0.9636085510694146 0.9724633893535163 0.8696735974032451 1.129356294861104 1.0 14.627103187395997 -4.761314369157682 5.604323390517781 1.0598198653618653 1.986508941582699 0.7534007392387434 0.15185477016095292 0.07651957573017237 7.9339389870953525 0.04028910229099073 0.27487870875491344 1.7325494175082343e-05 4.761314369157682 0.9266890762208337 QGLKS(ph)PQESLSDLGAIESLR ddPTM_PC-9_Lapatinib_30min_R1 1 QGLKSPQESLSDLGAIESLR 20 1 Q96JG6;F8WDT1;F2Z3F0;A0A3B3IRQ5;C9JA29;Q96JG6-2 Q96JG6 CCDC132 Coiled-coil domain-containing protein 132 1 QGLKS(0.939)PQES(0.053)LS(0.007)DLGAIESLR 58.123000000000005 0.008381200000000002 1887100.0 3349.3 3697.6 5778.2 3732.4 6179.3 5703.6 5090.8 6553.9 4791.3 3722.6 True False 3301.5383678136022 3689.038434379866 5303.1387004970165 4006.893146921404 5815.845722971228 5459.670323740991 5354.376714524292 6858.418120188256 4251.653339374245 4366.0464499472955 0.7561848930520326 0.8449379722985765 1.2146317638377468 0.9177394681565454 1.3320622649448526 1.2504837926785908 1.2263673270331164 1.5708532189965698 0.9737993830609769 1.0 12.092111763765903 -4.957182350545463 0.8019159776235877 1.2466291572993695 0.5178582042444589 0.40077015966332274 0.18464552949046195 1.8727056897255248 1.0993816053314722 0.06960708331440214 1.1627388943049057 1.1036151392776778e-05 4.957182350545463 -0.7287709530549106 QGMS(ph)PTFSR ddPTM_PC-9_Lapatinib_30min_R1 1 QGMSPTFSR 9 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 QGMS(0.762)PT(0.236)FS(0.002)R 77.387 0.023133 24005000.0 46628.0 39657.0 68243.0 49372.0 39896.0 42806.0 42816.0 39884.0 59767.0 28799.0 True False 45963.07616947206 39565.176653018796 62632.32396559801 53002.981580163876 37549.395718553875 40975.2871656597 45032.802979703025 41737.156243700454 53035.4110855886 33776.868777744625 1.3607855858964892 1.1713689896290225 1.854296334504105 1.5692094471198355 1.1116896585539908 1.2131168059206858 1.333243862124214 1.2356727474750653 1.5701695569997096 1.0 15.043747971507521 -6.250639072060165 24.900224890752792 1.2586855630060196 1.4923318888232104 0.24029168967718018 0.21235898842580092 1135.800913884644 2618599.7467713486 0.06475237199032978 0.08272246949189797 5.615144384596513e-07 6.250639072060165 0.2336463258171908 QGNFFAS(ph)PMLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QGNFFASPMLK 11 0 Q9H0H5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 QGNFFAS(1)PMLK 73.273 0.022147 10508000.0 83298.0 76818.0 79420.0 82005.0 94279.0 77809.0 81334.0 60701.0 76657.0 62496.0 True False 97398.70618950737 84443.98336752405 81313.67400202744 77410.52571379728 75805.70673746422 73728.55906508389 73629.45471283318 59107.663068025795 77777.96360420386 73826.03008193607 1.3193003346029726 1.1438239774481116 1.101422816746088 1.048553276234452 1.0268154288308744 0.9986797201915909 0.9973373162706335 0.8006344510523585 1.0535303539670455 1.0 16.171841960725587 -1.522878745281968 0.4075418011089908 0.9482777892985392 7.2313485376441315 0.7333137760199191 0.06421086820344166 36.19751108639046 0.47424015218487636 0.044204090662636364 183.68811900098558 0.029999999999887367 1.522878745281968 6.283070748345592 QGNFFAS(ph)PMLK ddPTM_PC-9_Lapatinib_30min_R1 2 QGNFFASPMLK 11 0 Q9H0H5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 QGNFFAS(1)PMLK;QGNFFAS(1)PMLK 96.756 0.0056729 9132600.0 101275.0 79916.0 85653.0 81218.0 68562.0 78153.0 59104.0 56091.0 65276.0 53931.0 True False 99830.79992843971 79730.95941202427 78610.94097014134 87191.04265530547 64529.31795807826 74810.57837354115 62164.11592190698 58697.192630262805 57923.92949324675 63252.90149145963 1.5782801669883684 1.2605107043633326 1.24280371519013 1.3784512741613595 1.020179571790726 1.1827216872200248 0.9827867885285918 0.9279762864030525 0.9157513430600114 1.0 15.948844039140281 -5.600321736554449 0.41358272994725404 0.9134203556416631 1.65580933197868 0.7709322670343659 0.09912885173018987 1.3654670726994926 0.30045417302772737 0.08726071561826111 0.47087550199721306 2.5100262503693168e-06 5.600321736554449 0.7423889763370168 QGPPS(ph)PCQQLVLTK ddPTM_PC-9_AZD4547_30min_R2 1 QGPPSPCQQLVLTK 14 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 QGPPS(1)PCQQLVLTK 168.42 8.489100000000001e-19 0.0 7819.5 9358.4 12464.0 18538.0 19622.0 18895.0 13428.0 19336.0 15319.0 13735.0 True False 10305.93834429606 12383.319786513572 12298.719216167072 14264.350509244916 16897.82400037444 17713.492663022145 14623.065986517124 16348.065497076966 16128.731065641654 13254.141830608622 0.7775636081165143 0.9342981193935916 0.9279151659419298 1.0762183392593065 1.2749089466774253 1.3364496086887545 1.1032827453790452 1.2334307046061144 1.2168823354820728 1.0 13.694155642224983 -5.831977669638798 2.1806500564704883 1.2079423376469258 0.8660159663488721 0.6863629191544034 0.09506739131946317 0.16689371821924476 1.619284599780845 0.028504760127720873 0.05107498104574962 1.4723882070907346e-06 5.831977669638798 -0.3419263712980537 QGPPSPCQQLVLT(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 QGPPSPCQQLVLTK 14 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 QGPPS(0.07)PCQQLVLT(0.93)K 157.07 0.00092184 4341900.0 24958.0 19978.0 28576.0 42741.0 40557.0 41211.0 35802.0 36510.0 32089.0 37677.0 True False 32894.124841350626 26435.497808916945 28197.06356877329 32887.72279186738 34926.36061477861 38634.069655242434 38988.30864233588 30868.218416336385 33785.159029008115 36357.93969798628 0.9047301666318704 0.7270900944472687 0.7755407430398211 0.9045540826860687 0.9606254068547521 1.0626033811641484 1.0723464796465156 0.8490090107621266 0.9292374460613163 1.0 15.149982827934199 -5.981237805541275 2.871582869287497 0.9796196404175376 0.7952482718976206 0.5373394875574813 0.07302316428124445 0.21205769040083391 3.5652115584803186 0.02369857887308203 0.03577289031020615 1.0441483209787763e-06 5.981237805541275 -0.18437136851991698 QGPSPVS(ph)PNALDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QGPSPVSPNALDR 13 0 A0A3B3ITG3;Q5VWQ8-2;Q5VWQ8;H0Y3A3;Q5VWQ8-3;Q5VWQ8-4;Q5VWQ8-5 A0A3B3ITG3 DAB2IP Disabled homolog 2-interacting protein 1 QGPS(0.167)PVS(0.833)PNALDR;QGPS(0.139)PVS(0.861)PNALDR;QGPS(0.17)PVS(0.83)PNALDR 120.32 0.00021445 18335000.0 29522.2 43546.5 50101.4 54914.5 74101.0 67221.0 73643.0 72116.0 73678.0 56352.0 True False 34519.72536997133 47869.50873120746 51296.0073866176 51837.81860021115 59581.44098847927 63695.81242419262 66667.00191085134 70223.0314132179 74755.40136491838 66568.17151781352 0.5185620181971488 0.7191050563616227 0.7705785845851404 0.7787177778548332 0.8950439771736165 0.9568508638869213 1.0014846493569585 1.0549040151181912 1.1229901567134672 1.0 16.022544920670008 -5.425993415341859 0.4357179558102382 1.08348510725446 0.3751404257371776 0.9239699310474867 0.048048365575825584 0.7759994329562993 0.17356095800620674 0.040100608382080336 0.2698220873570131 3.7497868753012943e-06 5.425993415341859 -0.7083446815172825 QGPSPVS(ph)PNALDR ddPTM_PC-9_Lapatinib_30min_R1 1 QGPSPVSPNALDR 13 0 A0A3B3ITG3;Q5VWQ8-2;Q5VWQ8;H0Y3A3;Q5VWQ8-3;Q5VWQ8-4;Q5VWQ8-5 A0A3B3ITG3 DAB2IP Disabled homolog 2-interacting protein 1 QGPS(0.016)PVS(0.984)PNALDR 113.65 0.00032093 33290000.0 79784.0 86531.0 75826.0 63921.0 77050.0 70963.0 64873.0 63555.0 81690.0 56473.0 True False 78646.26552940614 86330.64278594898 69591.87897682427 68621.963574205 72518.07048612834 67928.07791283254 68231.80651397315 66507.99731893449 72489.21196616412 66234.28280445762 1.1873951403926606 1.3034132647109884 1.0506927233179113 1.0360490167425305 1.0948721329137396 1.0255727855221968 1.0301584560885604 1.0041325202431037 1.0944364292457551 1.0 16.015290527543264 -5.27346888288896 24.369946289397305 1.0428045256583263 1.2454041949342831 0.8053554710584369 0.03999932765066651 174.6124570670372 353738.8136888513 0.00985599576243147 0.020795438397257584 5.327593950574649e-06 5.27346888288896 0.20259966927595685 QGPVS(ph)PGPAPPPSFIMSYK ddPTM_PC-9_AZD4547_30min_R2 2 QGPVSPGPAPPPSFIMSYK 19 0 P29375 P29375 KDM5A Lysine-specific demethylase 5A 1 QGPVS(1)PGPAPPPSFIMSYK;QGPVS(0.982)PGPAPPPS(0.017)FIMSYK 129.75 3.7113e-05 10801900.0 63052.0 55561.0 80874.0 113267.0 97395.0 89271.0 68546.0 101302.0 73505.0 84012.0 True False 83101.2244369276 73520.0066954266 79801.55791786712 87155.04310770548 83873.38541007398 83688.87025777434 74646.46120880287 85648.10358837889 77390.3242365683 81070.76545126246 1.0250455139329577 0.906862125776089 0.9843444486266958 1.0750489726176413 1.0345700443706356 1.0322940679286643 0.9207568325437644 1.0564610203399176 0.9546021158896453 1.0 16.30689414427419 -5.526027573390667 24.993756012926518 1.0124874828467103 0.9608661795462029 0.11237015777577342 0.05067952472611414 162.9019298390159 1293023.9164925008 0.01343006334340737 0.02342317094791458 2.9783273291908834e-06 5.526027573390667 -0.051621303300507404 QGPVS(ph)PGPAPPPSFIMSYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QGPVSPGPAPPPSFIMSYK 19 0 P29375 P29375 KDM5A Lysine-specific demethylase 5A 1 QGPVS(0.47)PGPAPPPS(0.281)FIMS(0.211)Y(0.038)K 71.946 0.0052412 7802600.0 33344.0 32486.0 36752.0 40716.0 46303.0 33655.0 41706.0 36032.0 33241.0 30038.0 True False 38988.480625980555 35710.99538750542 37628.30706273618 38434.81452305306 37230.259538866674 31890.072553758553 37755.30575470798 35086.19817905975 33727.086739206374 35483.65161932284 1.0987730644032458 1.006407000345443 1.0604406633911787 1.0831696505024626 1.049222891101566 0.8987257821117999 1.0640197395622073 0.9887989701700641 0.950496501911322 1.0 15.114866864442241 -6.555774464881613 24.975609310737106 0.9837160873621568 1.0591007684327152 0.4401275230699063 0.044719348804604694 187.36758272153762 142254.99470927462 0.014340426148666218 0.014340516519617796 2.781157186114489e-07 6.555774464881613 0.0753846810705584 QGPVS(ph)PGPAPPPSFIMSYK ddPTM_PC-9_Lapatinib_30min_R1 1 QGPVSPGPAPPPSFIMSYK 19 0 P29375 P29375 KDM5A Lysine-specific demethylase 5A 1 QGPVS(0.792)PGPAPPPS(0.2)FIMS(0.007)Y(0.001)K 112.14 0.00011336 2615000.0 17592.0 20331.0 31852.0 21857.0 26341.0 23206.0 25517.0 23677.0 29084.0 18581.0 True False 17341.13485402232 20283.92481863291 29233.251512275645 23464.436692814586 24791.674168398542 22213.53347582814 26838.14540436011 24777.119857138077 25808.25365190253 21792.701092373798 0.7957313221760622 0.9307668990940791 1.3414239652241005 1.0767108030048556 1.1376136470331442 1.0193107032336441 1.2315199153422947 1.1369457944710055 1.184261351656585 1.0 14.411557401660238 -5.043015081933145 6.751916753928663 1.142564959113938 0.8264782037661522 0.5932654994441442 0.0949406135400014 0.1146297422516717 14.672116583711814 0.022983690484115117 0.06517068942572685 9.05701147674836e-06 5.043015081933145 -0.31608675534778574 QGPVSPGPAPPPS(ph)FIMSYK ddPTM_PC-9_Lapatinib_30min_R1 1 QGPVSPGPAPPPSFIMSYK 19 0 P29375 P29375 KDM5A Lysine-specific demethylase 5A 1 QGPVS(0.468)PGPAPPPS(0.523)FIMS(0.008)Y(0.001)K 97.69 0.00059204 3538100.0 20476.0 20248.0 23477.0 20649.0 25702.0 27407.0 26446.0 24375.0 27165.0 19102.0 True False 20184.00848516149 20201.117000033417 21546.81168384074 22167.596343044712 24190.258892076195 26234.866498837437 27815.244478728207 25507.551485312357 24105.39163986838 22403.75524818494 0.9009207725029362 0.9016844174670239 0.9617500032985038 0.9894589588877355 1.0797412587354518 1.171003084447768 1.2415438470290234 1.1385391066249428 1.0759531771719966 1.0 14.451452952183272 -6.135333003429774 1.6019632815734084 1.140662168607447 0.9121692749543769 0.6845809604248221 0.06120085335062176 0.20917624161841386 1.0704195119830302 0.022050402844377318 0.033183506776919273 7.32262841571174e-07 6.135333003429774 -0.22849289365307002 QGPVSPGPAPPPSFIMS(ph)YK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QGPVSPGPAPPPSFIMSYK 19 0 P29375 P29375 KDM5A Lysine-specific demethylase 5A 1 QGPVS(0.001)PGPAPPPS(0.189)FIMS(0.737)Y(0.073)K 76.52199999999999 0.0032573 11975000.0 25358.0 22283.0 25162.0 25892.0 30781.0 25694.0 25247.0 20395.0 22082.0 23069.0 True False 29650.60855667033 24495.10897678335 25761.957507416395 24441.35518299658 24749.68401325735 24346.56140829809 22855.42138754887 19859.65286028873 22404.90747496032 27251.227085896484 1.088046731371433 0.8988626053268799 0.9453503662867776 0.8968900778653701 0.9082043878334647 0.8934115638740662 0.8386932931683431 0.7287617837424588 0.8221614169644378 1.0 14.734033573507991 -1.5228787453083954 0.4824645700265447 0.8449669667004315 6.908268916785699 0.42975650823802325 0.07028861965355596 93.8167435359062 1.0447798629823015 0.04100044209921024 571.2432571753841 0.029999999998061834 1.5228787453083954 6.063301950085268 QGPVSQSATQQPVTADKQQGHEPVS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 QGPVSQSATQQPVTADKQQGHEPVSPR 27 1 Q9BTA9-2;Q9BTA9;A0A0A0MRT2;Q9BTA9-5 Q9BTA9-2 WAC WW domain-containing adapter protein with coiled-coil 1 QGPVSQSATQQPVTADKQQGHEPVS(1)PR;QGPVSQSATQQPVTADKQQGHEPVS(1)PR;QGPVSQSATQQPVTADKQQGHEPVS(1)PR;QGPVSQSATQQPVT(0.007)ADKQQGHEPVS(0.992)PR 132.56 2.9681e-12 105382000.0 183110.0 93582.7 211709.0 340609.0 292429.0 230649.0 164866.0 201790.0 168784.0 233005.0 True False 241335.17107539528 123831.47766555868 208901.60033179657 262086.85740659235 251830.2810419685 216226.48156831926 179538.7546122385 170607.99217289794 177705.5776606346 224847.56587120256 1.0733279239217433 0.5507352378299348 0.929080995484113 1.1656201675615259 1.1200044797737423 0.9616580936979249 0.7984909861780851 0.7587717995160588 0.7903380095403305 1.0 17.77858774036701 -10.380923781693552 5.777884252858806 1.0000000242768121 0.9037777894278856 0.02469394724987084 0.1782337559273232 5.995236800205983e-08 1.1968259465906856e-08 0.1856263399699332 0.045020988983111604 4.159836088523042e-11 10.380923781693552 -0.09622223484892656 QGPVSQSATQQPVTADKQQGHEPVS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 QGPVSQSATQQPVTADKQQGHEPVSPR 27 1 Q9BTA9-2;Q9BTA9;A0A0A0MRT2;Q9BTA9-5 Q9BTA9-2 WAC WW domain-containing adapter protein with coiled-coil 1 QGPVSQSATQQPVT(0.009)ADKQQGHEPVS(0.991)PR;QGPVSQSATQQPVT(0.002)ADKQQGHEPVS(0.998)PR;QGPVSQS(0.001)AT(0.009)QQPVT(0.09)ADKQQGHEPVS(0.901)PR;QGPVSQSATQQPVTADKQQGHEPVS(1)PR;QGPVSQSATQQPVT(0.002)ADKQQGHEPVS(0.998)PR 146.78 6.737699999999999e-10 59670100.0 86404.1 49707.4 81006.26 121531.8 127356.2 155442.6 117571.5 129385.5 127959.8 106767.6 True False 101030.60757123596 54642.02216723778 82937.7564563518 114722.76725741201 102401.66684413135 147290.91641494198 106434.27637605257 125989.26772026933 129830.96999884203 126123.72070814332 0.801043665727448 0.43324143833087664 0.657590467444851 0.9096050022413017 0.8119144144271957 1.1678288238560661 0.8438878569269843 0.9989339595508356 1.0293937513885867 1.0 16.94448011037001 -5.851446635485888 2.009102445513524 0.9796634569602638 0.5972752427508747 0.6071803049730533 0.12435497990363248 0.2037379753960862 1.677964621453362 0.0372310434128791 0.06731061856674198 1.40784020797908e-06 5.851446635485888 -0.38238821420938907 QGPVSQSATQQPVTADKQQGHEPVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 QGPVSQSATQQPVTADKQQGHEPVSPR 27 1 Q9BTA9-2;Q9BTA9;A0A0A0MRT2;Q9BTA9-5 Q9BTA9-2 WAC WW domain-containing adapter protein with coiled-coil 1 QGPVSQSATQQPVTADKQQGHEPVS(1)PR;QGPVSQSATQQPVTADKQQGHEPVS(1)PR;QGPVSQSATQQPVTADKQQGHEPVS(1)PR 155.4 2.3584e-11 38779000.0 69423.0 34959.0 46842.0 34803.8 32903.0 33919.7 22306.9 25170.4 40950.6 20679.699999999997 True False 68433.01528938096 34878.05458337458 42990.83157534895 37363.387554073306 30967.710229786895 32469.033501682658 23461.842133500028 26339.908673062822 36338.31219906476 24254.158591031828 2.821496158381871 1.4380236878747474 1.7725138315556805 1.5404940729582235 1.2768000222954532 1.3386996452512827 0.9673327584398345 1.0859955654286113 1.4982301720621696 1.0 14.565944510943597 -1.5228787452803405 0.6777485682575632 1.2113900432665259 157.52523448195646 0.7848211057866561 0.2365432691759147 116.11541267194843 0.6732833089778584 0.09510661785676734 27392.5688220542 0.029999999999999798 1.5228787452803405 156.31384443868993 up QGQDVAPPPNPVPQRT(ph)SPTGPK ddPTM_PC-9_AZD4547_30min_R2 2 QGQDVAPPPNPVPQRTSPTGPK 22 1 Q9UPY8-2 Q9UPY8-2 MAPRE3 Microtubule-associated protein RP/EB family member 3 1 QGQDVAPPPNPVPQRT(0.495)S(0.495)PT(0.009)GPK;QGQDVAPPPNPVPQRT(0.427)S(0.427)PT(0.147)GPK 112.14 6.430599999999999e-06 104569000.0 142395.0 87023.0 158115.0 268117.0 237910.0 157688.0 141069.0 163934.0 119656.0 180212.0 True False 187673.64800000493 115151.48292248364 156018.29178949443 206306.76801635677 204880.30312552696 147827.7444322114 153623.867713136 138601.7671285587 125980.77187743451 173902.832732264 1.0791868369904134 0.6621599033971326 0.8971578515325042 1.186333567860743 1.1781309131459348 0.850059438996045 0.883389104705678 0.7970069546937523 0.7244319709926234 1.0 17.407921907572998 -6.95614634666639 24.999699132952983 0.8389236468853334 0.9891375775455781 0.18507292060312686 0.15520193279845695 259.8647348207771 148140.56796645635 0.059449711149007274 0.052429690326648536 1.1062509415289973e-07 6.95614634666639 0.1502139306602447 QGQDVAPPPNPVPQRT(ph)SPTGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QGQDVAPPPNPVPQRTSPTGPK 22 1 Q9UPY8-2 Q9UPY8-2 MAPRE3 Microtubule-associated protein RP/EB family member 3 1 QGQDVAPPPNPVPQRT(0.453)S(0.453)PT(0.094)GPK;QGQDVAPPPNPVPQRT(0.666)S(0.298)PT(0.036)GPK;QGQDVAPPPNPVPQRT(0.632)S(0.233)PT(0.136)GPK 102.06 5.1426000000000005e-05 65092000.0 156934.0 63728.2 108707.8 191743.0 209527.0 238353.0 187946.0 222102.0 206883.0 167741.0 True False 183499.82661221342 70054.71453099872 111299.80622862712 181000.26134919302 168471.6884521548 225853.34908352428 170142.39426879433 216272.05783652057 209908.27249081637 198151.11546297462 0.926060023348701 0.3535418630741382 0.561691545205679 0.9134455838226846 0.850218218850423 1.1398035714097503 0.8586496920356028 1.0914501153889893 1.0593342964553667 1.0 17.596241563208125 -5.869306209562873 3.241097616563956 0.9981101270410095 0.5857635930408823 0.5447246657676457 0.15703084410964227 0.17202023629138555 3.5742143362225325 0.04474057670091034 0.0715578121186692 1.3511195885568492e-06 5.869306209562873 -0.4123465340001272 QGQDVAPPPNPVPQRT(ph)SPTGPK ddPTM_PC-9_Lapatinib_30min_R1 2 QGQDVAPPPNPVPQRTSPTGPK 22 1 Q9UPY8-2 Q9UPY8-2 MAPRE3 Microtubule-associated protein RP/EB family member 3 1 QGQDVAPPPNPVPQRT(0.465)S(0.465)PT(0.069)GPK;QGQDVAPPPNPVPQRT(0.473)S(0.473)PT(0.055)GPK 89.96799999999999 0.00014826 86915000.0 231880.0 87944.0 110630.0 96461.0 93186.0 79936.0 58633.0 55014.0 111993.0 58484.0 True False 228573.34867841617 87740.37107126325 101534.4284441495 103555.06372446299 87704.98269072491 76517.32361991727 61668.72984652765 57570.15127848101 99379.1690014275 68592.88147496845 3.332318802816722 1.2791468908225159 1.480247312269603 1.5097056939101363 1.2786309716808006 1.115528637586696 0.899054370081134 0.839302126409284 1.4488262756200707 1.0 16.065771241754494 -3.1216252682552534 1.396785900373491 1.1640735382292207 199.99999999999753 0.8725451018007244 0.24179142594837058 45.77477783936848 1.2659342313673023 0.07346183728771263 28186.24265261531 0.0007557440414687683 3.1216252682552534 198.8359264617683 up QGQMYMADSQCT(ph)SPGIPAHMQSR ddPTM_PC-9_AZD4547_30min_R2 1 QGQMYMADSQCTSPGIPAHMQSR 23 0 H0YN48;F5H2B9;H0YNH8;Q9BZF9-2;Q9BZF9 H0YN48 UACA Uveal autoantigen with coiled-coil domains and ankyrin repeats 1 QGQMYMADS(0.001)QCT(0.554)S(0.445)PGIPAHMQSR 67.586 0.0035196 0.0 854.54 0.0 528.14 841.84 723.78 559.14 1097.0 2881.3 1121.3 605.97 True False 1126.265944463809 0.0 521.136518519454 647.7667942983463 623.2956403522071 524.1768874094839 1194.6308748294086 2436.061290687209 1180.5696288206798 584.755174742913 1.9260469904502695 0.0 0.8912046289262358 1.1077572671043676 1.0659087209039892 0.896404016672341 2.0429590475272437 4.165950804553753 2.0189126660396224 1.0 9.191688913420244 -7.389945123559484 4.157770671616583 2.652274090461332 0.9449930737888705 0.3525020788549311 0.8602400608005971 0.2073384768916348 5.993052868800651 0.361777463014197 0.23507923249889062 4.074317566807109e-08 7.389945123559484 -1.7072810166724615 QGQSQAASSSSVT(ph)SPIK ddPTM_PC-9_AZD4547_30min_R2 2 QGQSQAASSSSVTSPIK 17 0 O60583-2;O60583 O60583-2 CCNT2 Cyclin-T2 1 QGQSQAASSSSVT(0.979)S(0.021)PIK;QGQSQAASSSSVT(0.5)S(0.5)PIK 175.19 1.3819000000000001e-05 67018000.0 444304.0 365780.0 464771.0 503030.0 518134.0 507730.0 481870.0 525370.0 511440.0 472433.0 True False 585583.429902695 484011.2317822426 458607.83286402345 387064.2052360275 446200.0377438597 475981.56283653085 524755.4964941171 444186.13830157946 538473.6742745459 455893.26446741336 1.284474844318635 1.0616766456237896 1.0059543946098466 0.8490237417484248 0.9787379470611887 1.0440635998265628 1.1510490226416272 0.9743204669200136 1.1811397891644773 1.0 18.798336568896687 -10.421803714315292 15.115163753194167 1.000008720584584 1.0487102110051514 0.015820527503830117 0.11658396328167092 0.0 0.0 0.1162803708971306 0.0282021324349922 3.786136659859031e-11 10.421803714315292 0.04870149042056737 QGQSQAASSSSVT(ph)SPIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QGQSQAASSSSVTSPIK 17 0 O60583-2;O60583 O60583-2 CCNT2 Cyclin-T2 1 QGQSQAASSSSVT(0.881)S(0.119)PIK;QGQSQAASSSSVT(0.5)S(0.5)PIK;QGQSQAASSSSVT(0.701)S(0.299)PIK;QGQSQAASSSSVT(0.5)S(0.5)PIK 227.41 1.043e-28 80378000.0 402799.0 407055.0 373725.0 485327.0 505162.0 426355.0 505052.0 428494.0 397361.0 338346.0 True False 470984.91505711235 447464.730267224 382636.0213599545 458135.7016413638 406179.1324357588 403996.1932449186 457209.818300168 417246.486526921 403171.65289184434 399685.45145453786 1.178388938959627 1.1195422015957985 0.9573428804262528 1.1462406249066945 1.0162469786117785 1.010785335755137 1.1439240949008453 1.0439371385885448 1.0087223626094457 1.0 18.60850553406936 -5.018457182000372 11.416605143205974 1.0473108494190808 1.1637876825110902 0.37259293585922526 0.057850290424882184 0.6802338963084483 425.3433278571053 0.014132180935436386 0.040907405424039395 9.583912014378958e-06 5.018457182000372 0.1164768330920094 QGQTS(ph)PIKPK ddPTM_PC-9_Lapatinib_30min_R1 1 QGQTSPIKPK 10 1 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 QGQT(0.153)S(0.847)PIKPK 55.213 0.042908 14172000.0 49687.0 42913.0 40368.0 40584.0 45620.0 44347.0 36767.0 46787.0 46354.0 34989.0 True False 48978.454268520174 42813.63758506688 37049.09886498625 43568.68274425525 42936.72129237088 42450.38218790617 38670.615357687355 48960.89482434091 41133.12439074027 41036.80203008808 1.1935251249015284 1.0432985872943028 0.9028261714405021 1.0616978075511538 1.0462979366883847 1.034446645154797 0.9423398862643867 1.1930972298582843 1.0023472189811857 1.0 15.324630686637223 -8.472097562166697 24.999963727303303 0.9999948013137032 1.0462168438441788 0.04920166058932263 0.08660924049103692 1152.8610726228703 567563.017627062 0.08290224335970642 0.02140526719724583 3.37211547197145e-09 8.472097562166697 0.04622204253047557 QGS(ph)FSEDVISHK ddPTM_PC-9_AZD4547_30min_R2 3 QGSFSEDVISHK 12 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;E9PNZ4 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 QGS(0.916)FS(0.084)EDVISHK;QGS(0.924)FS(0.076)EDVISHK;QGS(0.967)FS(0.027)EDVIS(0.006)HK 161.48 0.00035748 60422000.0 199515.0 165223.0 221581.0 241928.0 280703.0 240500.0 221802.0 263071.0 250781.0 224034.0 True False 262956.61983019736 218628.10363813624 218642.6911615465 186155.23735034015 241732.2337364742 225461.49698104418 241541.94831259063 222419.42172018735 264036.77168044116 216190.6378506419 1.2163182570924478 1.0112746130532178 1.0113420883313118 0.861069837256079 1.1181438573833065 1.0428827965103982 1.117263683173288 1.02881153379939 1.221314550461035 1.0 17.721944522861357 QGS(ph)FSEDVISHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QGSFSEDVISHK 12 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;E9PNZ4 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 QGS(0.974)FS(0.026)EDVISHK;QGS(0.914)FS(0.086)EDVISHK;QGS(0.911)FS(0.089)EDVISHK;QGS(0.827)FS(0.173)EDVISHK 186.17 4.6087e-05 74230000.0 222108.0 276823.0 276721.0 304218.0 332767.0 262223.0 341016.0 301906.0 278015.0 227050.0 True False 259706.49756703747 304304.1579805269 283319.0781102365 287173.6517480628 267563.69513789634 248471.56426279098 308712.49573796336 293981.2873958478 282080.44342229416 268212.3676731895 0.9682868087704433 1.1345642284151283 1.0563236906936901 1.0706950400511628 0.9975814965546871 0.9263986087530005 1.151000225739487 1.0960765528682 1.05170557893886 1.0 18.03301623803786 -7.2962234840340265 24.999722585364335 1.0827019342272326 1.0327596345731598 0.11113015635374535 0.0645828039590269 1459.6942791128906 1049092.0192091656 0.02769364251033611 0.018671747902851914 5.055644361424887e-08 7.2962234840340265 -0.04994229965407282 QGS(ph)FSEDVISHK ddPTM_PC-9_Lapatinib_30min_R1 3 QGSFSEDVISHK 12 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;E9PNZ4 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 QGS(0.566)FS(0.434)EDVISHK;QGS(0.989)FS(0.011)EDVISHK;QGS(0.981)FS(0.019)EDVISHK 184.92 0.00025955 62522000.0 219782.0 287295.0 312068.0 303143.0 303862.0 321356.0 261403.0 257946.0 307140.0 249348.0 True False 216647.8683769175 286629.7860788516 286410.97365731536 325437.1474754029 285989.43457567727 307612.3529974243 274937.1682852978 269931.1128381694 272546.6588724161 292447.46956467436 0.7408095159770433 0.9801069111848267 0.9793587001578619 1.112805482501988 0.9779172820383426 1.0518550680411898 0.9401249690912297 0.9230071754082129 0.9319508193321632 1.0 18.157817980484815 -4.760686125890376 5.605709133374419 0.9906233383491163 0.7291860456191127 0.6512856508103262 0.05442334932864081 0.09862754198236678 10.224996276385477 0.01453402646321947 0.09997793919268862 1.7350575086951267e-05 4.760686125890376 -0.2614372927300036 QGS(ph)FTIEKPSPNIPIELIPHINK ddPTM_PC-9_AZD4547_30min_R2 3 QGSFTIEKPSPNIPIELIPHINK 23 1 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 QGS(0.689)FT(0.31)IEKPS(0.002)PNIPIELIPHINK;QGS(0.497)FT(0.497)IEKPS(0.006)PNIPIELIPHINK;QGS(0.467)FT(0.467)IEKPS(0.067)PNIPIELIPHINK 97.395 3.3762e-06 24009000.0 102970.9 94322.9 130671.3 157402.90000000002 166178.30000000002 142154.69999999998 124763.1 152125.69999999998 121779.5 139611.3 True False 135713.50427222624 124810.93284015877 128938.51318288926 121116.09325556293 143107.31149125623 133265.74413676155 135866.77420184933 128618.1685658194 128216.51575222341 134723.55088137265 1.0073480351755668 0.9264225298667923 0.9570599374746495 0.8989971869299124 1.062229361941816 0.9891792731480576 1.0084856976601166 0.9546821452106085 0.9517008341408782 1.0 17.039642543276173 -4.444987097265597 20.920177063268525 0.9720786606904913 2.5109425175528455 0.055924010477033215 0.04346664748476605 695.1389964938389 218712.96028084098 0.010751377222957381 8632.526637746882 3.589325982462751e-05 4.444987097265597 1.538863856862354 QGS(ph)FTIEKPSPNIPIELIPHINK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QGSFTIEKPSPNIPIELIPHINK 23 1 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 QGS(0.495)FT(0.495)IEKPS(0.01)PNIPIELIPHINK;QGS(0.463)FT(0.463)IEKPS(0.073)PNIPIELIPHINK;QGS(0.496)FT(0.496)IEKPS(0.009)PNIPIELIPHINK;QGS(0.823)FT(0.174)IEKPS(0.003)PNIPIELIPHINK 81.316 6.8669e-05 28718100.0 93537.8 76748.1 76445.7 111860.0 98194.0 89641.4 101937.9 96549.0 96880.7 76713.0 True False 109371.90208423857 84367.14415747725 78268.4554099318 105592.84685501312 78953.59059152682 84940.4471793341 92281.60414551513 94014.69105212144 98297.39695722227 90620.45964022627 1.2069228352897095 0.9309944409068834 0.8636951933444903 1.1652208262265382 0.8712556844776745 0.9373208601739335 1.0183307887852677 1.0374554645316374 1.08471527674296 1.0 16.46754918797958 -10.251902958216307 4.90568588669778 0.9999999970556958 1.0050590402917319 0.0 0.11042312900981785 3.3367213539820124e-09 9.508746328581276e-10 0.10434733872037398 0.025307932143342236 5.5988269160701814e-11 10.251902958216307 0.00505904323603612 QGS(ph)FTIEKPSPNIPIELIPHINK ddPTM_PC-9_Lapatinib_30min_R1 1 QGSFTIEKPSPNIPIELIPHINK 23 1 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 QGS(0.813)FT(0.185)IEKPS(0.002)PNIPIELIPHINK 78.40100000000001 0.00012547 2312900.0 4433.2 2311.2 2913.9 2016.8 2992.9 2557.4 1897.2 2483.9 3694.9 2580.8 True False 4369.981755050686 2305.8485583997044 2674.3303899792763 2165.1221998475753 2816.863506267796 2448.0259635905745 1995.4277329291053 2599.3110619227627 3278.741452978088 3026.8878413001617 1.443721070673572 0.7617885694136775 0.8835247720412895 0.7152964739247075 0.9306137703000741 0.8087600505670061 0.6592341168716692 0.8587404615581201 1.0832054654426 1.0 11.563619503006274 -4.756746944537247 24.997012676144593 0.8424893793489748 1.443721980018387 0.6738361129372423 0.12242492985183484 81.88116645307117 436135.8309777024 0.029960311201582185 0.2357975428987693 1.7508665894412635e-05 4.756746944537247 0.6012326006694121 QGS(ph)PDQVS(ph)PVSEMTSTSLYQDKQEGK ddPTM_PC-9_AZD4547_30min_R2 1 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 QGS(0.994)PDQVS(0.71)PVS(0.175)EMT(0.079)S(0.021)T(0.021)SLYQDKQEGK 76.82300000000001 0.00036797 0.0 15111.0 9868.5 20063.0 27871.0 30115.0 18817.0 11601.0 17554.0 16132.0 21207.0 True False 19915.98367167437 13058.299635964391 19796.951511068666 21445.771552657527 25934.052072738566 17640.3700153526 12633.466525885115 14841.432650790706 16984.70458586927 20464.549384908423 0.973194341936569 0.6380936804596455 0.9673778366049889 1.0479474113645866 1.267267193865682 0.8619965034930839 0.6173342148057099 0.7252264573064833 0.8299574188716139 1.0 14.320839279542502 -6.997467475482628 24.999784973142688 0.7658650798726433 0.9732161943376271 0.20610523760303545 0.16942013917819682 122.6878140993106 1211093.607444365 0.06392087704811761 0.056042342041703885 1.005848388638542e-07 6.997467475482628 0.20735111446498378 QGS(ph)PDQVS(ph)PVSEMTSTSLYQDKQEGK ddPTM_PC-9_Lapatinib_30min_R1 1 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 QGS(0.872)PDQVS(0.588)PVS(0.095)EMT(0.224)S(0.035)T(0.092)S(0.088)LY(0.007)QDKQEGK 49.943999999999996 0.039224 4381800.0 34249.0 16600.0 22667.0 22546.0 25123.0 22614.0 18501.0 16341.0 25752.0 15244.0 True False 33760.602979502626 16561.563719900954 20803.4067571503 24204.108051251194 23645.314533718407 21646.851935808732 19458.89125391176 17100.262515753413 22851.53857941803 17878.90508864679 1.8882925331339675 0.9263186776699008 1.1635727497854769 1.3537802192719814 1.322525871493849 1.2107481877933683 1.0883715282021533 0.9564490907562444 1.278128524432343 1.0 14.125970767550161 -4.750155138380008 24.999769423889347 1.1560978870613141 1.8882941244971962 0.7065500792916459 0.14363923968672165 296.0189691562989 655776.1433754653 0.037415538379266554 0.5673762233907694 1.7776442877209746e-05 4.750155138380008 0.7321962374358821 QGS(ph)PDQVSPVSEMT(ph)STSLYQDKQEGK ddPTM_PC-9_Lapatinib_30min_R1 2 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 QGS(0.631)PDQVS(0.343)PVS(0.114)EMT(0.632)S(0.136)T(0.136)S(0.007)LYQDKQEGK;QGS(0.928)PDQVS(0.064)PVS(0.047)EMT(0.938)S(0.008)T(0.015)S(0.001)LYQDKQEGK 118.37 6.2525e-12 23152600.0 385610.0 192728.0 242030.0 241330.0 207650.0 217620.0 151221.0 146835.0 246600.0 154863.0 True False 380111.1306877872 192281.75015717262 222131.22766281787 259078.21325327986 195436.4352556075 208312.89989699743 159050.4834499643 153657.49014752143 218825.31118687827 181630.86320802342 2.092767297221082 1.0586402925198382 1.2229817319560334 1.426399724569691 1.0760089546663247 1.1469025484860182 0.8756798301828383 0.8459877767113629 1.2047804394138442 1.0 17.47064984454329 -4.76002963503259 24.999329367132592 1.0989407101728663 2.092768506487188 0.7737032897275012 0.1618295115142894 18.159278837072787 321907.73464919854 0.044063420267920705 0.2685100469870178 1.737682250159775e-05 4.76002963503259 0.9938277963143218 QGS(ph)PDQVSPVSEMTSTSLYQDK ddPTM_PC-9_AZD4547_30min_R2 4 QGSPDQVSPVSEMTSTSLYQDK 22 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QGS(0.997)PDQVS(0.001)PVSEMT(0.001)STSLYQDK;QGS(0.999)PDQVS(0.001)PVSEMTSTSLYQDK;QGS(0.999)PDQVS(0.001)PVSEMTSTSLYQDK;QGS(0.996)PDQVS(0.004)PVSEMTSTSLYQDK 106.36 2.4542e-05 41867300.0 188627.6 217455.0 205206.0 201290.0 210440.0 254027.0 234621.0 240868.0 232997.0 216760.0 True False 248607.25310218573 287743.076185706 202484.83436078145 154885.70039949872 181224.03845881164 238142.65153265532 255501.81447889731 203647.385196004 245312.74574719727 209171.2983766094 1.188534254133531 1.375633647727469 0.9680335492119522 0.7404730075377245 0.8663905605850417 1.138505394291159 1.2214955706727537 0.9735914381013226 1.1727839701291896 1.0 17.67432537893516 -5.2685114619638735 24.85350839606301 1.0065812948446666 1.282083955777944 0.3693841111678161 0.1420574500566999 516.0678955730233 1813629.8000206626 0.04102372567108372 0.0884463210670173 5.388756231008682e-06 5.2685114619638735 0.27550266093327735 QGS(ph)PDQVSPVSEMTSTSLYQDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QGSPDQVSPVSEMTSTSLYQDK 22 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QGS(1)PDQVSPVSEMTSTSLYQDK;QGS(0.994)PDQVS(0.005)PVSEMTSTSLYQDK;QGS(0.998)PDQVS(0.002)PVSEMTSTSLYQDK;QGS(0.998)PDQVS(0.002)PVSEMTSTSLYQDK 134.66 5.102e-06 35423400.0 156206.0 197969.0 149511.0 169410.0 186483.0 125652.0 172297.0 128557.0 124044.0 125414.0 True False 182648.5905908686 217622.0539884586 153075.9092636254 159918.50693463068 149942.99482941683 119062.58792229586 155975.78083774322 125182.51496740092 125857.90883180755 148150.5654233222 1.2328578704304807 1.4689248965512218 1.03324552846781 1.0794323091355273 1.012098701081383 0.8036593554812903 1.0528193422148706 0.8449681890157296 0.8495270232157663 1.0 17.176704606857278 -5.590940932390693 1.1932096237035184 0.9167879150823952 1.3711023944972456 0.6718164156025679 0.10800410676519102 0.31347562374375043 0.8150349864254142 0.03574485129140659 0.12439777285398777 2.5648328510871913e-06 5.590940932390693 0.45431447941485037 QGS(ph)PDQVSPVSEMTSTSLYQDK ddPTM_PC-9_Lapatinib_30min_R1 3 QGSPDQVSPVSEMTSTSLYQDK 22 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QGS(0.989)PDQVS(0.011)PVSEMTSTSLYQDK;QGS(0.978)PDQVS(0.022)PVSEMTSTSLYQDK;QGS(0.899)PDQVS(0.101)PVSEMTSTSLYQDK 95.445 9.2969e-05 25169100.0 78696.0 114967.0 103149.0 104676.0 112957.0 126981.0 113821.0 116472.0 104655.0 93069.0 True False 77573.78060892121 114700.8009750516 94668.48738665432 112374.2222288996 106313.09134200655 121550.31863716866 119714.09444956967 121883.71432194085 92867.65183399328 109155.85264335266 0.7106699158164221 1.0507984519145857 0.867278163232958 1.029484168806435 0.9739568586337343 1.1135483411440403 1.0967263005192602 1.1166026499758488 0.8507803254253514 1.0 16.73602996026873 -4.350008600413586 2.1112113894883677 1.0180964792817644 6.750807103527397e-18 0.48336393993718685 0.09090460498711103 3.733239277216309 5.318368519985811 0.02421063291771894 11.501652276381774 4.4667474648113203e-05 4.350008600413586 -1.0180964792817644 QGS(ph)PDQVSPVSEMTSTSLYQDKQEGK ddPTM_PC-9_AZD4547_30min_R2 1 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QGS(0.978)PDQVS(0.007)PVS(0.01)EMT(0.001)S(0.002)T(0.001)S(0.001)LYQDKQEGK 45.77 0.01892 6214400.0 16396.0 11606.0 18104.0 28490.0 17725.0 17403.0 12032.0 14963.0 15870.0 15223.0 True False 21609.58694201398 15357.41253230002 17863.92913105654 21922.07066611218 15264.189705770927 16314.787658881944 13102.824690927479 12650.812165533864 16708.855800752866 14690.047403520573 1.4710358890220523 1.0454297464431264 1.2160566021574117 1.492307687234447 1.0390837610308021 1.1106014303923886 0.8919525125417427 0.8611825284173016 1.1374269491294133 1.0 13.842551430904072 -6.429048151694277 7.495188391086559 0.9944219852453325 1.2810769439531466 0.5131990777479987 0.1423971832635906 0.2482287342960035 17.487329274718117 0.04487969694366613 0.05082338975530437 3.7235042021865696e-07 6.429048151694277 0.2866549587078141 QGS(ph)PDQVSPVSEMTSTSLYQDKQEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QGS(0.405)PDQVS(0.357)PVS(0.09)EMT(0.143)S(0.006)TSLYQDKQEGK 122.89 3.7268e-12 31357000.0 119520.0 51996.0 77263.0 150530.0 148920.0 158180.0 134710.0 182260.0 152700.0 109100.0 True False 139752.37537239678 57157.819250407345 79105.24294155935 142096.2921248448 119740.1950311649 149884.76234002452 121949.29358405761 177475.8681204329 154932.9486199821 128878.96636487519 1.0843691512603957 0.443499981902285 0.6137948276028289 1.1025561123957919 0.9290902806604059 1.1629885509453797 0.9462311579905237 1.3770739564900976 1.2021585289669712 1.0 16.97565730293713 -5.767957308446611 24.950906426957488 1.107320049730626 0.6868491635450474 0.45572998031731926 0.19408611508011034 120.47233753441817 461174.9227940538 0.054208223331457264 0.08258441234284267 1.7062501067394461e-06 5.767957308446611 -0.4204708861855785 QGS(ph)PDQVSPVSEMTSTSLYQDKQEGK ddPTM_PC-9_Lapatinib_30min_R1 3 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QGS(0.75)PDQVS(0.056)PVS(0.183)EMT(0.009)S(0.001)TSLYQDKQEGK;QGS(0.865)PDQVS(0.13)PVS(0.005)EMTSTSLYQDKQEGK;QGS(0.962)PDQVS(0.038)PVSEMTSTSLYQDKQEGK 142.34 1.5762e-12 25433500.0 147220.0 71507.0 95659.0 83502.0 78206.0 82913.0 49357.0 60079.0 87064.0 56385.0 True False 145120.61580315873 71341.429934877 87794.28627441822 89643.01563450634 73606.07683891186 79367.0042696431 51912.4639543442 62870.489669172595 77257.93549543538 66131.07212171017 2.1944391818731317 1.0787883463249694 1.3275799629081808 1.3555354957730594 1.1130331699967666 1.2001469464092918 0.7849935331277029 0.9506951520982955 1.1682546950584274 1.0 16.01304067038953 -3.037750908380248 1.51966773042155 1.0969894971948704 199.99569133640594 0.7753533646605612 0.17246317033669767 126.8356526853651 2.10034653230543 0.05192090249335116 86425.49840628533 0.0009167461433759534 3.037750908380248 198.89870183921107 up QGS(ph)PGSVSK ddPTM_PC-9_AZD4547_30min_R2 4 QGSPGSVSK 9 0 O00425 O00425 IGF2BP3 Insulin-like growth factor 2 mRNA-binding protein 3 1 QGS(0.881)PGS(0.119)VSK;QGS(0.998)PGS(0.002)VSK;QGS(0.861)PGS(0.138)VS(0.001)K;QGS(0.981)PGS(0.019)VSK 116.71 0.0019018000000000001 1183154000.0 1592520.0 1192910.0 1337420.0 1814960.0 1671470.0 1679250.0 1544180.0 1342530.0 1855810.0 2036160.0 True False 2098908.2335262313 1578494.8288735165 1319684.9369452947 1396549.0128524755 1439415.2421723544 1574246.2320391606 1681609.0285269602 1135072.8367703094 1953904.3278887975 1964874.6581588734 1.0682148221571293 0.8033565002831262 0.6716382296781545 0.7107573030439863 0.7325735696144176 0.8011942265641823 0.8558352674275219 0.5776820582712869 0.9944167785845661 1.0 20.906005853400842 -8.374856899167215 11.390063969888914 0.9994893506696436 0.7746654027533092 0.34004335076891856 0.12229680108354286 0.6687793231378847 63.743942637638995 0.11741094132612662 0.03031996714777546 4.21835476098843e-09 8.374856899167215 -0.22482394791633442 QGS(ph)PGSVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 QGSPGSVSK 9 0 O00425 O00425 IGF2BP3 Insulin-like growth factor 2 mRNA-binding protein 3 1 QGS(0.972)PGS(0.027)VS(0.001)K;QGS(0.891)PGS(0.108)VSK;QGS(0.999)PGS(0.001)VSK;QGS(0.884)PGS(0.116)VSK;QGS(0.92)PGS(0.078)VS(0.002)K;QGS(0.911)PGS(0.087)VS(0.002)K 117.95 0.0018273 1029987000.0 1766040.0 2207290.0 1951690.0 2024310.0 3214980.0 2706000.0 2048320.0 2132420.0 2500590.0 2397440.0 True False 2064995.6911200478 2426415.1637285836 1998225.691425546 1910894.473601567 2585027.7479270315 2564092.5963592534 1854288.301047417 2076446.234485753 2537156.398098491 2832076.893875396 0.7291453475665771 0.8567617528238411 0.7055690104131271 0.674732553248832 0.9127675005990731 0.9053753455297485 0.6547450406651992 0.7331885087499717 0.8958642343311034 1.0 21.433429005969202 -8.498376413994137 3.84502721951762 0.9991702124364606 0.7748691601742813 0.4189538587579561 0.0872318261727454 0.19548868446911022 7.235587366847274 0.08817378484114317 0.023166304017741383 3.1741217865806323e-09 8.498376413994137 -0.22430105226217933 QGS(ph)PGSVSK ddPTM_PC-9_Lapatinib_30min_R1 4 QGSPGSVSK 9 0 O00425 O00425 IGF2BP3 Insulin-like growth factor 2 mRNA-binding protein 3 1 QGS(0.936)PGS(0.058)VS(0.006)K;QGS(0.817)PGS(0.183)VSK;QGS(1)PGSVSK;QGS(0.624)PGS(0.374)VS(0.002)K 127.52 0.0013595999999999999 1371994000.0 1701320.0 2196890.0 1932620.0 1799060.0 2071030.0 1575470.0 2158170.0 2107950.0 2157240.0 1662380.0 True False 1677058.8648161236 2191803.2361815246 1773727.4437289375 1931368.8738882293 1949216.0872016395 1508090.8206999449 2269909.4825930884 2205893.052449811 1914268.9144557216 1949720.1680178845 0.8601536222098207 1.1241629809931881 0.9097343674359876 0.9905877292389547 0.9997414599158825 0.7734909067659146 1.1642232151194873 1.1313895648380945 0.9818172606799246 1.0 20.894835646538688 -7.2969737839832565 24.99985377086486 1.080306620665872 0.9544471330459733 0.2672939185649771 0.10079566450912861 839.8762447584822 590882.7598615135 0.04111228988196774 0.027719061747390538 5.0469176216509314e-08 7.2969737839832565 -0.12585948761989874 QGS(ph)PVAAGAPAK ddPTM_PC-9_AZD4547_30min_R2 5 QGSPVAAGAPAK 12 0 Q9NZI8 Q9NZI8 IGF2BP1 Insulin-like growth factor 2 mRNA-binding protein 1 1 QGS(1)PVAAGAPAK;QGS(1)PVAAGAPAK;QGS(1)PVAAGAPAK;QGS(1)PVAAGAPAK;QGS(1)PVAAGAPAK 123.1 0.00037051 1509427000.0 365488.0 325303.0 383770.0 474780.0 458312.0 423163.0 412896.0 428423.0 351945.0 391284.0 True False 481705.581377335 430450.8331031188 378680.95904913626 365326.8062778777 394683.28984097514 396702.5507151324 449642.9441144601 362220.0695311436 370548.0941900419 377585.26625757955 1.2757531196906584 1.140009612582382 1.002901842019464 0.9675345913223758 1.0452825496949654 1.0506303772046854 1.1908381610624725 0.9593066835506389 0.9813626942139816 1.0 18.526442944878518 -4.9318647026140106 2.6864496334003833 1.029237541406612 1.2880212872594559 0.6090541476746549 0.06317519341697377 0.24665262359274512 2.999472529288933 0.01760290264223763 0.12416141556786331 1.1698637863016445e-05 4.9318647026140106 0.2587837458528439 QGS(ph)PVAAGAPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QGSPVAAGAPAK 12 0 Q9NZI8 Q9NZI8 IGF2BP1 Insulin-like growth factor 2 mRNA-binding protein 1 1 QGS(1)PVAAGAPAK;QGS(1)PVAAGAPAK;QGS(1)PVAAGAPAK;QGS(1)PVAAGAPAK 153.79 0.00019278 1148060000.0 480266.0 482629.0 398932.0 533892.0 558789.0 444595.0 566404.0 493840.0 426047.0 374571.0 True False 561565.54811412 530541.2175360583 408444.0518380357 503979.7621412186 449298.306750401 421279.6555352332 512750.11271015194 480877.22326673026 432277.1313732649 442477.75719759474 1.2691384797978555 1.1990234738491896 0.9230838052174433 1.138994568525078 1.0154144461317192 0.952092277368656 1.158815566137432 1.0867828166376907 0.9769465794417896 1.0 18.755245408983264 -5.077464239160982 5.923187402677182 1.039904346155014 1.2534803285991898 0.5542399984708097 0.07350768880320359 0.14489510207091771 8.522662353478848 0.018447347267732245 0.05179100736542602 8.36634483389818e-06 5.077464239160982 0.21357598244417586 QGS(ph)PVAAGAPAK ddPTM_PC-9_Lapatinib_30min_R1 4 QGSPVAAGAPAK 12 0 Q9NZI8 Q9NZI8 IGF2BP1 Insulin-like growth factor 2 mRNA-binding protein 1 1 QGS(1)PVAAGAPAK;QGS(1)PVAAGAPAK;QGS(1)PVAAGAPAK;QGS(1)PVAAGAPAK 139.64 7.3014e-05 1718730000.0 728670.0 592420.0 620500.0 591470.0 622230.0 604950.0 578689.0 542530.0 573880.0 475324.0 True False 718279.0321782866 591048.2878881762 569484.8851992656 634968.6768860787 585631.6547512474 579077.6987073265 608650.6848729772 567737.9244031389 509243.5911756919 557483.1200705818 1.2884318938434347 1.0602084020290063 1.021528481664457 1.138991754235871 1.0504921739641224 1.0387358430404328 1.0917831642972744 1.018394824817761 0.9134690770748676 1.0 19.08856859703183 -4.76198432088448 4.728489730267662 1.041287321653897 1.306707698780859 0.6468934929001511 0.0558091471722667 0.12409092761407596 6.626491215378229 0.014275029959533099 0.11113599583612883 1.7298788110335025e-05 4.76198432088448 0.2654203771269621 QGS(ph)PVEPK ddPTM_PC-9_AZD4547_30min_R2 2 QGSPVEPK 8 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 QGS(1)PVEPK;QGS(1)PVEPK 92.943 0.0075956999999999995 130176000.0 1038560.0 943890.0 925260.0 1139990.0 1182830.0 1178720.0 1025790.0 1029030.0 1099330.0 1136540.0 True False 1368800.4766100314 1248983.983725028 912990.4478458561 877182.9181699284 1018614.4716319887 1105014.452064433 1117083.322781455 870017.0582569871 1157438.3394733227 1096750.0805358544 1.2480514028695193 1.1388045516393257 0.8324507689115315 0.7998020093523502 0.9287571432265681 1.0075353279432089 1.0185395402347872 0.7932682875499866 1.0553346291142436 1.0 20.064803381620386 -5.08824503530196 4.39138674915699 0.9241431410834153 1.2274026091555983 0.5889085191331853 0.09000882297235797 0.14009857806676893 4.654206759252202 0.023708344651415185 0.07322128695137804 8.16121773585393e-06 5.08824503530196 0.30325946807218296 QGS(ph)PVEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QGSPVEPK 8 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 QGS(1)PVEPK;QGS(1)PVEPK 103.21 0.0040413 115094000.0 655580.0 629920.0 585660.0 806080.0 765020.0 723990.0 830700.0 819670.0 733280.0 619890.0 True False 766556.745704783 692454.2946037502 599624.3555279186 760917.9509466193 615119.822742021 686022.6898884454 752010.0822528169 798154.5310121531 744002.8327705318 732271.1499534593 1.0468209020026296 0.9456255304442355 0.8188556323242131 1.0391204828907716 0.8400164649134626 0.9368424386677623 1.0269557694586386 1.0899712914579267 1.0160209545573633 1.0 19.482018432042743 -7.2870206878767085 4.8511520230148735 1.042261979038909 0.9326466966128565 0.2971282653246903 0.07133833152514535 0.23013346112754435 14.79521298041832 0.029565200500235384 0.02035658455479574 5.163917700561745e-08 7.2870206878767085 -0.10961528242605245 QGS(ph)PVEPK ddPTM_PC-9_Lapatinib_30min_R1 2 QGSPVEPK 8 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 QGS(1)PVEPK;QGS(1)PVEPK 107.11 0.0038152 124937000.0 682240.0 600070.0 545320.0 634300.0 676650.0 636800.0 629900.0 595830.0 621980.0 547840.0 True False 672511.132492506 598680.5747831917 500485.8945960731 680948.5379627727 636850.7773450848 609565.5484533032 662513.1398756296 623514.4369843566 551926.0626602374 642533.4140490858 1.0466555011583103 0.9317501030965153 0.778925863858403 1.0597869668311946 0.9911558892039708 0.9486908153335912 1.0310952323874278 0.970400018662257 0.8589842187072212 1.0 19.293411956026503 -4.753381878513411 24.7253623320813 0.9528881904152006 1.0466556994911835 0.11591046553829043 0.07815342611608009 628.3147437474763 1927878.499961447 0.01980828960592094 0.2127287823531126 1.764485612438631e-05 4.753381878513411 0.09376750907598297 QGS(ph)VVSSR ddPTM_PC-9_AZD4547_30min_R2 1 QGSVVSSR 8 0 Q9BZ67-2;Q9BZ67-3;Q9BZ67 Q9BZ67-2 FRMD8 FERM domain-containing protein 8 1 QGS(1)VVSSR 126.71 0.0035475000000000003 11644000.0 25264.0 24515.0 30351.0 48314.0 39346.0 34703.0 33136.0 41564.0 41755.0 34298.0 True False 33297.426476155226 32438.994333046292 29948.525909008877 37175.95374385904 33883.48706139703 32533.015924046413 36085.03980706224 35141.23884570268 43962.08405547802 33097.237459498705 1.006048511356922 0.9801118408369306 0.9048648228015125 1.1232343421214983 1.0237557470728624 0.9829526093788724 1.0902734662135996 1.06175746204514 1.3282704971759258 1.0 15.014423183596847 -7.694936159327679 1.9654762181518937 1.159560926074577 1.0054979793038972 0.27839751690776926 0.09310234664434473 0.407417721750496 3.09932867365743 0.06115519225092869 0.026631610364329834 2.0186630824798612e-08 7.694936159327679 -0.15406294677067978 QGS(ph)VVSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QGSVVSSR 8 0 Q9BZ67-2;Q9BZ67-3;Q9BZ67 Q9BZ67-2 FRMD8 FERM domain-containing protein 8 1 QGS(0.613)VVS(0.386)S(0.001)R 104.07 0.0038640000000000002 8095600.0 18820.0 27966.0 21630.0 24933.0 35250.0 26280.0 23879.0 26433.0 22650.0 24818.0 True False 22005.854288056467 30742.279659144777 22145.741232231816 23536.084843876644 28343.015544242277 24901.830536704038 21617.008251011182 25739.161758078546 22981.213400409884 29317.3069408201 0.7506096768191387 1.0486051710411575 0.7553811568346027 0.8028051448035992 0.9667673637778351 0.849390108954102 0.7373463154254674 0.8779510959187214 0.7838787323405847 1.0 14.839464964550286 -6.996193056917599 24.970759039507215 0.833015418051464 0.8697727126036033 0.0 0.1070649240633926 543.1505626676386 3562633.9868285567 0.03633799332358449 0.031905826588888506 1.0088043426137475e-07 6.996193056917599 0.036757294552139386 QGS(ph)VVSSR ddPTM_PC-9_Lapatinib_30min_R1 1 QGSVVSSR 8 0 Q9BZ67-2;Q9BZ67-3;Q9BZ67 Q9BZ67-2 FRMD8 FERM domain-containing protein 8 1 QGS(0.949)VVS(0.051)SR 88.338 0.011051 8522100.0 47273.0 33727.0 42924.0 41887.0 45992.0 39180.0 48648.0 38202.0 53192.0 43816.0 True False 46598.87835119352 33648.90720368071 39394.95441143158 44967.50971093581 43286.84098375103 37504.36273304087 51166.7554035079 39977.00438325757 47200.95682340801 51389.53721884992 0.9067775440892828 0.6547812847658441 0.7665948468004754 0.8750323926723653 0.8423279003157325 0.7298054188214036 0.9956648409890662 0.7779210817371172 0.918493517900264 1.0 15.649187039766531 -8.649049390421569 0.25455830641398336 1.0434994498892465 0.7539959718638547 0.31206977308703154 0.0896848618071688 3.6060001007753475 0.7044985627722081 0.3618573195007604 0.19429713581143487 2.2436267513660592e-09 8.649049390421569 -0.2895034780253918 QGS(ph)YSPALPLQPLGGHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QGSYSPALPLQPLGGHK 17 0 H3BMJ2;Q6ZRI6-2;Q6ZRI6 H3BMJ2 C15orf39 Uncharacterized protein C15orf39 1 QGS(0.373)Y(0.283)S(0.343)PALPLQPLGGHK 51.193000000000005 0.043136 5747100.0 24877.0 24497.0 26483.0 28145.0 30595.0 31302.0 27374.0 29216.0 22506.0 24121.0 True False 29088.184756853367 26928.90026496709 27114.4551573368 26568.126897321134 24600.12937804518 29660.4680159783 24780.9365494024 28449.110956910787 22835.107672831113 28493.946358269077 1.0208548998833866 0.9450744353336019 0.9515865165327673 0.9324130312897476 0.8633458162914702 1.040939280331406 0.8696912753964968 0.9984264937964523 0.80140207276709 1.0 14.798367825613605 QGSATSASSAGPHS(ph)AASEGTVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QGSATSASSAGPHSAASEGTVQR 23 0 Q9H1R2-3;Q9H1R2-4;Q9H1R2-2 Q9H1R2-3 1 QGS(0.037)AT(0.125)S(0.022)AS(0.052)S(0.306)AGPHS(0.442)AAS(0.009)EGT(0.007)VQR 54.058 0.011124 5270900.0 14700.0 19480.0 16969.0 17486.0 25477.0 15876.0 18569.0 17966.0 17613.0 12700.0 True False 17188.419661765663 21413.845661165 17373.60531529087 16506.316110376883 20484.964738174753 15043.434611899298 16810.00989208202 17494.411536550502 17870.556804477666 15002.409466855317 1.1457106073354335 1.427360432234196 1.158054334783637 1.1002443405403735 1.365444982916377 1.0027345704124806 1.1204873409981388 1.16610678939278 1.1911791131923788 1.0 13.872906603385688 -1.5228817894030493 0.039535127040889954 0.5419106095142429 2.1999577737355875 0.23292465901861026 0.11411783966727666 1119.41450949624 3.383872824533735 39.20601054220041 125.29115559350602 0.029999789720189643 1.5228817894030493 1.6580471642213448 QGSES(ph)PAQAGR ddPTM_PC-9_Lapatinib_30min_R1 2 QGSESPAQAGR 11 0 Q92817;K7EKI0 Q92817 EVPL Envoplakin 1 QGS(0.055)ES(0.945)PAQAGR;QGS(0.283)ES(0.717)PAQAGR 124.42 0.00051256 13494600.0 21219.2 22352.0 23302.0 21596.6 20902.7 19388.4 17287.1 16314.5 22230.0 16005.0 True False 20916.610316875285 22300.245317302797 21386.199508321188 23184.886008145644 19673.24428228936 18559.203328567877 18182.141451570067 17072.53122901039 19726.22330772222 18771.442924678027 1.1142782364043573 1.187987807159225 1.1392943842481948 1.2351147485665819 1.04804113147987 0.9886934852604683 0.9686064904295008 0.9094948799362595 1.0508634518334754 1.0 14.196251931170936 -6.487852118648246 3.7276377873798934 0.9785603126260279 1.1679849912305391 0.7943943014844628 0.04443131208934633 0.09642204022883277 2.8235940494764087 0.014302746368452933 0.015574386775171131 3.2519801151327117e-07 6.487852118648246 0.18942467860451118 QGSFS(ph)EDVISHK ddPTM_PC-9_Lapatinib_30min_R1 1 QGSFSEDVISHK 12 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;E9PNZ4 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 QGS(0.012)FS(0.987)EDVIS(0.002)HK 197.73 9.9717e-06 9275500.0 27690.0 35032.0 40544.0 38061.0 43463.0 42818.0 39900.0 27436.0 48685.0 36305.0 True False 27295.135522275923 34950.88555635967 37210.628824365915 40860.13290777396 40906.59179154574 40986.773953633085 41965.8267678006 28710.77672004224 43201.582624222094 42580.27087662829 0.6410277567599467 0.8208234667559083 0.8738936615076891 0.9596024653333408 0.9606935547701927 0.9625766372503315 0.9855697463595764 0.6742741680349709 1.0145915405140091 1.0 15.37789750714908 -4.682586820705802 1.4091182010786691 0.9260248919855649 0.4748129869307287 0.48471896487174926 0.0923273474236304 1.3910227313610126 2.1211010002429305 0.026665314484506205 0.9532126290312585 2.0768884890062092e-05 4.682586820705802 -0.4512119050548362 QGSFTIEKPSPNIPIELIPHINK ddPTM_PC-9_AZD4547_30min_R2 1 QGSFTIEKPSPNIPIELIPHINK 23 1 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 0 94.837 4.5363e-06 2242400.0 9139.1 9714.6 10472.0 13456.0 13794.0 11291.0 12544.0 11450.0 11197.0 11163.0 False True 12045.14369491095 12854.654470642934 10333.134437716753 10353.927093127608 11878.941201771737 10584.971985085098 13660.391699052041 9680.665594824752 11788.850560871451 10772.186767752764 1.1181707070813944 1.1933189377224847 0.9592420425395572 0.961172259296762 1.1027418534305506 0.9826205405918039 1.2681168636943154 0.8986722755127536 1.0943785895137035 1.0 13.395023528108695 -5.24952140680944 24.95833519570113 1.0362198940005387 1.1557448283995941 0.1943354747659175 0.09953356304457552 1201.68728123768 2516533.438742412 0.024474202144998243 0.06364659978951466 5.629613677813948e-06 5.24952140680944 0.11952493439905543 QGSFTIEKPSPNIPIELIPHINK ddPTM_PC-9_Lapatinib_30min_R1 1 QGSFTIEKPSPNIPIELIPHINK 23 1 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 0 52.853 0.007947599999999999 1463500.0 33191.0 26798.0 27313.0 26692.0 27530.0 26771.0 22761.0 25908.0 28764.0 25784.0 False True 32717.69025351606 26735.95087746421 25067.43057122895 28655.018721901753 25910.739526062487 25626.06673624905 23939.45320957167 27111.780261803993 25524.295421651914 30240.730044979588 1.0819080824058243 0.8841040159314135 0.8289294118873468 0.9475637221482659 0.8568159395465407 0.8474023840738382 0.7916294736920869 0.8965319362819071 0.8440370117946054 1.0 14.884205347797538 -4.76356076604229 5.186051225605485 0.8697887041203101 1.0938260940750466 0.5318050247727604 0.0573020483031605 0.11728616177979204 8.903059832442313 0.013532025527368624 0.0952008764815582 1.723610908268722e-05 4.76356076604229 0.22403738995473654 QGSGRES(ph)PSLASR ddPTM_PC-9_AZD4547_30min_R2 3 QGSGRESPSLASR 13 1 H3BUF6;Q8WWM7-7;H3BSK9;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 QGS(0.058)GRES(0.935)PS(0.007)LASR;QGS(0.019)GRES(0.972)PS(0.009)LASR;QGSGRES(0.98)PS(0.019)LAS(0.001)R 84.62 0.0040093 643042000.0 63221.0 56633.1 84696.0 114025.0 108903.0 84710.0 77294.0 101433.0 76970.0 92663.0 True False 83323.96292150937 74938.6420543686 83572.87570061664 87738.29791868872 93783.69825261319 79413.0703087908 84173.01626168135 85758.86054845921 81038.47706263061 89418.89657442189 0.9318384157442627 0.8380627017914316 0.9346220866308756 0.9812053299680965 1.0488129673414002 0.8881016580505061 0.9413336496679482 0.9590686514128869 0.906279099465107 1.0 16.448292122741215 -5.487108062455657 8.719666183085451 0.9587750677580971 0.8851000237954235 0.28275093826515807 0.04770929917036114 0.45551616426632446 104.18422671858043 0.012650796699284159 0.0258265056062605 3.2575563542262436e-06 5.487108062455657 -0.07367504396267355 QGSGRES(ph)PSLASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QGSGRESPSLASR 13 1 H3BUF6;Q8WWM7-7;H3BSK9;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 QGS(0.001)GRES(0.831)PS(0.168)LASR;QGS(0.048)GRES(0.868)PS(0.079)LAS(0.004)R 94.45 0.009009399999999999 392330000.0 63804.0 59750.0 76777.0 93965.0 92545.0 82165.0 69513.0 76600.0 69081.0 61219.0 True False 74604.75701355773 65681.58512600654 78607.65485839384 88700.4456886401 74411.47158984108 77856.12275678414 62928.225409461906 74589.3311644088 70091.17893658794 72317.52009066251 1.0316277012821757 0.9082389031546342 1.0869794036057314 1.2265415846317567 1.0289549682643078 1.0765872869973698 0.8701656988592875 1.0314143940624372 0.9692143597943698 1.0 16.142057585313523 -7.20332181337087 24.999888018438302 0.970315846952514 1.060341151863406 0.22975301390328817 0.08257495820611728 449.83462985552404 193501.06704371056 0.03371343545526259 0.02611430851172298 6.261497141148856e-08 7.20332181337087 0.090025304910892 QGSGRES(ph)PSLASR ddPTM_PC-9_Lapatinib_30min_R1 2 QGSGRESPSLASR 13 1 H3BUF6;Q8WWM7-7;H3BSK9;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 QGS(0.002)GRES(0.948)PS(0.05)LASR;QGS(0.001)GRES(0.987)PS(0.012)LASR 65.528 0.018656 647240000.0 93842.0 63037.0 89673.0 68880.0 82298.0 64365.0 61186.0 62454.0 66544.0 59121.0 True False 92503.79587148486 62891.04169948175 82300.43208778997 73945.66497694427 77457.39344409328 61612.258992143354 64353.91169460268 65355.84083953634 59049.11398061481 69339.98607621939 1.3340613563118333 0.9069953032634175 1.1869115750517212 1.0664216877064594 1.117066757973547 0.8885530914935342 0.9280923654046317 0.9425418800588794 0.8515882007202494 1.0 16.08139992639058 -6.75704383296573 24.983958501786343 0.918935042940912 1.1108166188200235 0.47059098095451624 0.10576062500814044 98.50999466522131 559923.0920617703 0.032995450684925584 0.031911076030689364 1.7496700870269404e-07 6.75704383296573 0.19188157587911148 QGSIT(ph)SPQANEQS(ph)VTPQRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QGSITSPQANEQSVTPQRR 19 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 QGS(0.033)IT(0.773)S(0.194)PQANEQS(0.556)VT(0.445)PQRR 74.77600000000001 0.016937 13115000.0 24902.0 30165.0 32221.0 34733.0 35759.0 24127.0 29349.0 26437.0 22853.0 23221.0 True False 29117.41676308085 33159.58184646004 32989.27083882296 32787.02261590532 28752.280648129356 22861.737646843925 26568.850251640673 25743.05676231689 23187.181891371598 27430.783482665134 1.0614868795665857 1.20884559740757 1.202636842643248 1.195263804135418 1.0481756988931556 0.8334336371139885 0.968577885076846 0.9384732586506397 0.8452978350408665 1.0 14.74350820882325 -6.512998888653361 4.055888116698487 0.9168582188455059 1.1700600556656682 0.7855356822999439 0.06147692555108216 0.09340060052523814 3.5477673913586845 0.020011461725932916 0.02137358760187092 3.069029841937029e-07 6.512998888653361 0.2532018368201623 QGSIT(ph)SPQANEQSVT(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 1 QGSITSPQANEQSVTPQR 18 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 QGS(0.024)IT(0.573)S(0.403)PQANEQS(0.016)VT(0.984)PQR 152.13 2.6019e-12 0.0 5871.4 9421.8 8456.8 6754.0 6994.7 9435.0 10861.0 12090.0 11799.0 8533.8 True False 7738.383067293294 12467.212596659007 8344.657306425035 5196.969648259802 6023.606642310626 8845.027958487108 11827.607959455056 10221.768300561675 12422.671051864094 8235.034259486565 0.9396904522138276 1.5139235859640865 1.0133117900283397 0.631080513389852 0.7314610300948746 1.074073000764732 1.4362548578143353 1.2412538889909825 1.5085147991404493 1.0 13.007558936543111 -7.085859398186392 5.608287432183458 1.3132564652457543 0.9732475522717848 0.2783548466813699 0.2505695856045839 0.32745537811357806 16.55618886771614 0.10450022563670616 0.08109411441320893 8.206171742025173e-08 7.085859398186392 -0.3400089129739695 QGSIT(ph)SPQANEQSVTPQR ddPTM_PC-9_AZD4547_30min_R2 1 QGSITSPQANEQSVTPQR 18 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QGS(0.001)IT(0.717)S(0.274)PQANEQS(0.008)VTPQR 243.61 6.285499999999999e-53 11593000.0 30239.0 41263.0 41084.0 44450.0 41078.0 45261.0 38288.0 54668.0 41088.0 38466.0 True False 39854.37298972679 54600.45780805585 40539.199316191276 34202.73924565415 35375.02875789323 42430.822515006344 41695.55782631578 46220.31674566633 43259.827797185484 37119.31704813917 1.0736828195960768 1.4709445687604057 1.09213214412369 0.9214269540923239 0.9530086103689943 1.143092758414138 1.1232846168005135 1.2451823045592214 1.1654262857552802 1.0 15.179882546363888 -5.472246225430291 24.808841412685545 1.0820150242362405 1.2746201213108808 0.2608721130919154 0.12926384025653737 435.6027081793086 213434.7371010091 0.03501921127404196 0.07289675817115288 3.370961361292316e-06 5.472246225430291 0.19260509707464024 QGSIT(ph)SPQANEQSVTPQR ddPTM_PC-9_Lapatinib_30min_R1 1 QGSITSPQANEQSVTPQR 18 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QGS(0.015)IT(0.655)S(0.329)PQANEQS(0.001)VTPQR 189.55 1.5244999999999998e-10 12540000.0 7049.0 22011.0 19783.0 15896.0 26536.0 22746.0 25764.0 25861.0 23577.0 21869.0 True False 6948.479967371721 21960.03488185182 18156.518104588366 17065.044867501507 24975.20465178328 21773.20660351576 27097.93385577982 27062.59647022207 20921.509983183394 25649.027511389177 0.2709061762394821 0.8561741715977614 0.7078832948549865 0.6653291186156651 0.9737291069103227 0.848890141891251 1.0564897185184612 1.0551119904333688 0.8156843363317935 1.0 14.646616506313809 -4.600936320133168 0.5252647624495737 0.9795814232726292 7.960069631164449e-13 0.6351662959305117 0.13602334795172902 3.543366368143387 0.6517401400200693 0.07940953805110022 2.2245429467574356 2.506476746543621e-05 4.600936320133168 -0.9795814232718332 QGSIT(ph)SPQANEQSVTPQRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QGSITSPQANEQSVTPQRR 19 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QGS(0.036)IT(0.457)S(0.457)PQANEQS(0.049)VTPQRR 54.292 0.028432 5015800.0 980.78 2002.6 1018.2 1496.6 3589.1 2262.1 6491.7 4240.2 1952.1 3738.0 True False 1146.8066827120094 2201.404893277669 1042.4777495450032 1412.7503540426649 2885.841619569927 2143.471493800541 5876.759180162038 4128.899242863262 1980.6457694896299 4415.669810008282 0.25971296135248356 0.4985438196234922 0.2360859834180056 0.3199402162817095 0.6535456100066762 0.48542386229656076 1.330887369984536 0.9350561569402124 0.44854933786045814 1.0 12.108416580583956 -6.788505289817004 1.8094030016351617 0.9094382724216123 0.3486314315564101 0.5240484634961785 0.23693890255323258 0.2839040851600291 1.919347137765881 0.10042195651829995 0.08999317544013581 1.6274014933583265e-07 6.788505289817004 -0.5608068408652023 QGSITS(ph)PQANEQSVT(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 2 QGSITSPQANEQSVTPQR 18 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 QGS(0.005)IT(0.044)S(0.95)PQANEQS(0.274)VT(0.727)PQR;QGSIT(0.034)S(0.966)PQANEQS(0.012)VT(0.988)PQR 163.96 4.3727e-06 8157500.0 11712.8 32489.0 29462.0 26436.6 38778.0 36983.0 42746.0 39645.0 29922.0 29759.0 True False 11545.773324135538 32413.7737166182 27039.748086608844 28380.835753912317 36497.154280481314 35401.32330158371 44959.17872221564 41487.05143118804 26551.869267371305 34902.80349862503 0.3307978777289445 0.9286868236213495 0.7747156496375444 0.8131391438235144 1.0456797340625974 1.0142830876888822 1.2881251422679205 1.188645245440596 0.7607374367052577 1.0 15.091055302262948 -4.613187434575789 0.6590436541008076 1.0677394228234958 1.54609615457946e-12 0.562894517733021 0.1677253067529652 3.151243314060989 0.8874211797119022 0.07743000577296871 2.6622663763732546 2.436758925084465e-05 4.613187434575789 -1.0677394228219497 QGSITS(ph)PQANEQSVT(ph)PQRR ddPTM_PC-9_AZD4547_30min_R2 2 QGSITSPQANEQSVTPQRR 19 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 QGS(0.024)IT(0.302)S(0.673)PQANEQS(0.067)VT(0.933)PQRR;QGS(0.005)IT(0.127)S(0.867)PQANEQS(0.051)VT(0.95)PQRR 104.49 0.0010308 34707000.0 65066.0 75548.0 93578.0 94091.0 92610.0 97394.0 83261.0 109874.0 87391.0 87968.0 True False 85755.63454312507 99967.41357833896 92337.09457722091 72399.77364145884 79752.70006496161 91303.93778366628 90671.06770207071 92895.49795334286 92010.30984773756 84888.26709537537 1.0102177542012394 1.1776352256787332 1.0877486104584568 0.8528831618168715 0.9395020394909965 1.0755778260979534 1.0681224956588893 1.0943267088839386 1.0838990239294235 1.0 16.37327754377472 -9.812688063687082 14.86178997710959 1.000000796201402 1.0431039590218771 0.022295139896123528 0.08605759997855858 0.0 0.0 0.09149950626356593 0.02219188994214983 1.539259831967368e-10 9.812688063687082 0.043103162820475216 QGSITS(ph)PQANEQSVT(ph)PQRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QGSITSPQANEQSVTPQRR 19 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 QGS(0.001)IT(0.041)S(0.957)PQANEQS(0.032)VT(0.969)PQRR 127.37 0.00013005 10447000.0 67573.0 74410.0 77471.0 71184.0 87340.0 57833.0 69361.0 56916.0 59500.0 50170.0 True False 79011.77427241427 81796.93304144191 79318.2024504036 67195.7912616417 70226.35397543602 54800.13567082209 62790.623949846624 55422.01530748678 60370.07493705904 59265.42385449856 1.333185002884559 1.3801796683722374 1.3383554405201967 1.1338110299626447 1.1849464562650804 0.9246560997414089 1.0594815638879547 0.9351492270358572 1.0186390480438052 1.0 15.854903044490458 -6.111480207989318 1.083516780700393 0.9856190029936337 1.3758389323617133 0.8642230245676169 0.05995233980960935 0.16362489435200092 0.39563771817484866 0.023420101473039336 0.04191873389004806 7.736059333513905e-07 6.111480207989318 0.3902199293680796 QGSITS(ph)PQANEQSVTPQR ddPTM_PC-9_AZD4547_30min_R2 1 QGSITSPQANEQSVTPQR 18 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QGSIT(0.019)S(0.91)PQANEQS(0.068)VT(0.002)PQR 170.79 6.468e-08 13466000.0 8302.7 10888.0 12086.0 11137.0 12066.0 12575.0 12413.0 13632.0 12183.0 8885.2 True False 10942.785893111695 14407.333073555283 11925.731743147884 8569.536714934771 10390.844174320559 11788.683262106559 13517.73295283267 11525.487632196586 12826.968507912547 8574.131852444396 1.2762558450733437 1.6803255794868495 1.3908967051571504 0.9994640696470845 1.2118829466517052 1.3749127567644912 1.5765716209482952 1.3442162810816571 1.4960078441359297 1.0 13.065774887658474 -11.386399137866356 2.7224558614513197 0.8421113950610309 1.3714667916773629 0.27609971258650456 0.1808375949119024 58996251.062392734 40521475.21278099 60396130.26144282 0.048163773822911544 4.1077202799095075e-12 11.386399137866356 0.5293553966163319 QGSITS(ph)PQANEQSVTPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QGSITSPQANEQSVTPQR 18 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QGS(0.007)IT(0.213)S(0.78)PQANEQS(0.001)VTPQR 185.96 1.2581999999999999e-10 10182000.0 39501.0 68307.0 51964.0 45486.0 58712.0 32421.0 48260.0 34113.0 32321.0 30115.0 True False 46187.73911968746 75088.0675347636 53203.018834567454 42937.56688760171 47207.80506761851 30720.785686091396 43688.46342785712 33217.56989571117 32793.6334796754 35574.611109791156 1.298334336730817 2.1107206851263993 1.4955333923502667 1.2069722070913673 1.3270083240523622 0.863559283649798 1.228079859904155 0.9337437250738838 0.921826900045849 1.0 15.118560365309152 -5.930989112801164 1.3222394031252243 1.0151733057093868 1.724098195155576 0.5849640517469318 0.22593866579586372 0.29262776834084425 1.037763104578321 0.07767905125745324 0.15521889845550696 1.172224751332465e-06 5.930989112801164 0.7089248894461893 QGSITS(ph)PQANEQSVTPQR ddPTM_PC-9_Lapatinib_30min_R1 1 QGSITSPQANEQSVTPQR 18 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QGSIT(0.212)S(0.788)PQANEQSVTPQR 168.47 9.8445e-08 9202200.0 6000.5 24784.0 19566.0 18741.0 33137.0 28033.0 35903.0 33961.0 22951.0 22426.0 True False 5914.93176964307 24726.614170724428 17957.359006944134 20119.275658143302 31187.946809848614 26834.093938114725 37761.88166527183 35538.95204072589 20366.01669525564 26302.304219233352 0.22488264603516459 0.9400930794741278 0.682729499942935 0.7649244526428692 1.1857496039089486 1.0202183700123317 1.4356872063573332 1.3511725719733068 0.7743054192325534 1.0 14.68290157222461 -4.9133348614192185 0.6021927934546196 1.1682960583395272 2.012073654645835e-17 0.5271123540846832 0.23022438117637659 2.6133273240552684 0.8021685284627488 0.12136563894064936 2.078862310301991 1.2208579584044548e-05 4.9133348614192185 -1.1682960583395272 QGSITSPQANEQS(ph)VTPQRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QGSITSPQANEQSVTPQRR 19 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QGSITSPQANEQS(0.5)VT(0.5)PQRR 172.99 2.6959e-08 21335000.0 22003.0 25691.0 26999.0 26703.0 29950.0 24204.0 26978.0 18912.0 23695.0 21424.0 True False 25727.673320940805 28241.432694095995 27642.758554277683 25206.917482294077 24081.51249787394 22934.699631293188 24422.448536194133 18415.58003892034 24041.49454846412 25308.001607709324 1.0165825701980216 1.1159092342357482 1.0922537062688167 0.9960058432513907 0.9515374967630091 0.9062232564544653 0.9650089688928487 0.7276584032344373 0.9499562597285675 1.0 14.627305972163109 -6.223621396078423 1.4150617559846423 0.893396611451652 1.0808215683331042 0.47903907088847353 0.07343039706865474 0.3233135166928901 1.3012344198497303 0.027169659826061628 0.03914815355977188 5.975559896229684e-07 6.223621396078423 0.18742495688145222 QGSITSPQANEQSVT(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 3 QGSITSPQANEQSVTPQR 18 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QGSITSPQANEQS(0.469)VT(0.531)PQR;QGSITSPQANEQSVT(1)PQR;QGSITSPQANEQSVT(1)PQR 290.67 5.751899999999999e-106 22522100.0 25513.9 32864.9 33954.4 21788.3 28793.7 37236.0 29788.6 44653.0 32935.5 28547.4 True False 33626.78947791232 43487.836216852214 33504.14247058917 16765.344060879324 24796.191770440397 34907.62703362225 32439.727691835295 37752.90487386108 34676.40329084412 27547.964215152315 1.2206633207188664 1.578622502817556 1.2162111947336114 0.608587405223135 0.9001097713348143 1.2671581377480472 1.177572594420329 1.3704426424764884 1.2587646411915594 1.0 14.74965808762996 -5.516709393952001 24.99948629528987 1.0879995296676068 1.3990864521662472 0.24663617660459192 0.22045553904527776 396.9399987062378 1608480.43100526 0.06543961287237181 0.11858291128952128 3.0429205000932227e-06 5.516709393952001 0.31108692249864034 QGSITSPQANEQSVT(ph)PQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QGSITSPQANEQSVTPQR 18 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QGSITSPQANEQSVT(1)PQR;QGSITSPQANEQS(0.002)VT(0.998)PQR;QGSITSPQANEQS(0.005)VT(0.995)PQR;QGSITSPQANEQSVT(1)PQR 262.58 2.727099999999999e-152 20470100.0 50065.1 103871.0 78184.0 60815.0 66789.0 38776.4 60724.0 34651.0 38039.1 42529.9 True False 58540.13259920165 114182.62642047553 80048.20307447121 57407.7327148902 53702.174898848156 36742.897322049124 54971.78311631152 33741.447965769315 38595.34987459301 50240.234203496846 1.165204213859479 2.272732765495909 1.593308716480857 1.1426645123181864 1.0689077340151083 0.7313440692418534 1.0941784804117283 0.6716021232922681 0.7682159624945912 1.0 15.61655556916585 -5.885126891376499 2.074222379628518 0.872277251819402 1.7637700604654902 0.6099880204382471 0.28202792711505087 0.1923255630813511 1.6844688739211808 0.08451898372769741 0.14677318218828703 1.302786077158169e-06 5.885126891376499 0.8914928086460883 QGSITSPQANEQSVT(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 2 QGSITSPQANEQSVTPQR 18 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QGSITSPQANEQS(0.003)VT(0.997)PQR;QGSITSPQANEQSVT(1)PQR 181.86 9.7054e-09 19000400.0 16928.5 54780.0 50295.0 46737.0 66403.0 58770.0 71382.0 76123.0 52502.0 50289.0 True False 16687.09648569331 54653.16027567314 46159.939244314424 50174.1948900615 62497.306093320956 56256.5440995613 75077.81068519158 79659.9524806742 46588.67188943017 58981.38664411953 0.28292140004065197 0.9266170801551015 0.7826187526385766 0.8506784554388549 1.0596106610788196 0.953801653375847 1.2729068432757316 1.350594772573329 0.7898877008527415 1.0 15.847972119905673 -4.70477659527019 0.6458956453535285 1.1024679373537414 3.720677316167001e-12 0.5651522372283204 0.1845255270387703 2.847869674299135 0.8389811687572635 0.08641733980734545 2.3808056343629382 1.9734376279518385e-05 4.70477659527019 -1.1024679373500208 QGSITSPQANEQSVT(ph)PQRR ddPTM_PC-9_AZD4547_30min_R2 5 QGSITSPQANEQSVTPQRR 19 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QGSITSPQANEQSVT(1)PQRR;QGSITSPQANEQS(0.012)VT(0.988)PQRR;QGSITSPQANEQS(0.028)VT(0.972)PQRR;QGSITSPQANEQS(0.279)VT(0.721)PQRR;QGSITSPQANEQS(0.001)VT(0.999)PQRR 185.2 2.5957e-10 240926500.0 61961.399999999994 57057.9 77933.0 83593.0 78842.0 69475.6 72778.0 91827.0 61625.0 69690.0 True False 81663.83632281673 75500.7503469517 76899.55749948241 64321.9253489757 67896.14921198251 65131.27974909024 79255.10101033225 77637.24712453912 64882.37169006904 67250.17431198507 1.2143289910887698 1.1226848275023167 1.1434848799459196 0.9564573773530353 1.0096055498235685 0.9684923558255043 1.1785114584633531 1.1544542139677831 0.9647911303406979 1.0 16.03725038667909 -5.616600337987205 8.475666353875063 1.0420990239489534 1.159703919972323 0.3699148099287006 0.07560075262179507 0.3181129369013614 25.38903029089796 0.02199527555073129 0.038176346458994814 2.4176846993757026e-06 5.616600337987205 0.11760489602336954 QGSITSPQANEQSVT(ph)PQRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QGSITSPQANEQSVTPQRR 19 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QGSITSPQANEQSVT(1)PQRR;QGSITSPQANEQS(0.188)VT(0.812)PQRR;QGSITSPQANEQS(0.033)VT(0.967)PQRR 205.65 6.9806e-20 90860000.0 51188.0 70793.0 67103.0 64514.0 72860.0 50464.0 68647.0 47540.0 52640.1 50786.0 True False 59853.11739091574 77820.86118536223 68702.99000954471 60899.48973721003 58583.60602988629 47817.57900320522 62144.2591987589 46292.125372793635 53409.86187721486 59993.09977824521 0.997666691872117 1.2971635316897185 1.1451815336012674 1.0151082368191533 0.9765057356001126 0.7970513139003512 1.035856780670862 0.7716241625104385 0.8902667485866838 1.0 15.872508955467662 -6.051391534558696 1.8576943506280206 0.8956998025409093 1.163727668803057 0.5105800788775956 0.10288878966290521 0.251091646676799 1.7302665656403589 0.032701038252261505 0.05079995092649944 8.883998272781093e-07 6.051391534558696 0.2680278662621476 QGSITSPQANEQSVT(ph)PQRR ddPTM_PC-9_Lapatinib_30min_R1 5 QGSITSPQANEQSVTPQRR 19 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QGSITSPQANEQS(0.002)VT(0.998)PQRR;QGSITSPQANEQS(0.001)VT(0.999)PQRR;QGSITSPQANEQS(0.038)VT(0.962)PQRR;QGSITSPQANEQS(0.001)VT(0.998)PQRR;QGSITSPQANEQS(0.111)VT(0.889)PQRR 167.05 2.6558e-07 229230400.0 69368.6 103860.2 122876.0 120050.0 126441.1 115166.7 107313.0 128502.0 137021.5 106993.9 True False 68379.39104335668 103619.71808805184 112773.60959507643 128878.87747506007 119004.08309076715 110241.28870769021 112869.14205345827 134472.67203961484 121588.69576963826 125487.65305458958 0.5449093148121139 0.8257363618313528 0.8986829130194801 1.027024367241893 0.9483330048335357 0.8785030720092685 0.8994442027245341 1.0716008210075982 0.9689295545016273 1.0 16.937185896356247 -4.53103053493332 1.325329654558651 0.9656323957117153 0.13419577818848405 0.8416387099782726 0.0554759285231949 0.9260703503678652 0.9435844980573624 0.017332248261181123 1.2181034839512477 2.9442146209045126e-05 4.53103053493332 -0.8314366175232313 QGSPDQVS(ph)PVS(ph)EMTSTSLYQDKQEGK ddPTM_PC-9_AZD4547_30min_R2 1 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 QGS(0.142)PDQVS(0.977)PVS(0.872)EMT(0.007)S(0.001)TSLYQDKQEGK 147.35 3.4113000000000004e-09 9859300.0 61779.0 43019.0 75269.0 131420.0 112360.0 78904.0 64682.0 74434.0 65200.0 88088.0 True False 81423.43691697254 56924.05046760421 74270.88388010908 101123.1494187596 96760.75347477669 73970.12040662068 70438.57269436264 62931.93562316026 68646.33889156189 85004.06593190027 0.9578769676994474 0.6696626784089135 0.8737333098820247 1.1896272055947639 1.138307355230456 0.8701950853254564 0.8286494524955246 0.7403402994108215 0.8075653574801571 1.0 16.375244229735053 -6.987260087989358 24.986695348965018 0.8263464067013582 0.9614574155887227 0.13392190193450237 0.1463217393228219 482.8628100234558 947031.521420208 0.05758353678632363 0.050754908016194276 1.0297692329724592e-07 6.987260087989358 0.1351110088873645 QGSPDQVS(ph)PVSEMT(ph)STSLYQDKQEGK ddPTM_PC-9_Lapatinib_30min_R1 1 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 QGS(0.216)PDQVS(0.72)PVS(0.21)EMT(0.656)S(0.075)T(0.073)S(0.031)LY(0.02)QDKQEGK 60.8 0.0017541 5606600.0 29916.0 17559.0 21967.0 19693.0 15821.0 25287.0 13939.0 13690.0 26451.0 11046.0 True False 29489.392354077507 17518.343214321747 20160.958055072173 21141.288913922202 14890.439885282758 24205.53395687607 14660.693215949183 14326.087377802103 23471.809838621703 12955.286382130174 2.2762439582002285 1.3522158212176312 1.5561954757620113 1.6318658106302737 1.1493717271909814 1.8683904965824516 1.1316379108509214 1.1058101654597723 1.8117553828063158 1.0 13.661253286809055 -4.758919190442465 24.967341618614764 1.4145312099876048 2.2762451120434104 0.44664532530660583 0.29196655222432677 61.28924026501102 607060.3163914456 0.06874659881418994 0.4539296019261909 1.7421310030883946e-05 4.758919190442465 0.8617139020558056 QGSPDQVS(ph)PVSEMTSTSLYQDK ddPTM_PC-9_AZD4547_30min_R2 2 QGSPDQVSPVSEMTSTSLYQDK 22 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QGS(0.016)PDQVS(0.974)PVS(0.01)EMTSTSLYQDK;QGS(0.007)PDQVS(0.993)PVSEMTSTSLYQDK 117.03 9.455899999999999e-07 13335400.0 45614.0 53051.0 58187.0 59452.0 55551.0 66365.0 62124.0 79745.0 66156.0 55422.0 True False 60118.30316986007 70198.6982811519 57415.402361289576 45746.25992424368 47838.70253005814 62215.1860588232 67652.9156498652 67422.24260779911 69652.87109984928 53481.69264914391 1.1240912579984021 1.3125743558955139 1.0735524535087548 0.8553629785869529 0.8944874434677023 1.1632987472362488 1.2649733450601275 1.2606602234919795 1.3023684862929301 1.0 15.706757505748895 -6.990427965130048 24.761417223546793 1.2266384841573041 1.0539740517025689 0.2135571070048239 0.14027945907113376 287.3809724611368 743407.320082247 0.05428352874771622 0.04781298833060178 1.0222851093074413e-07 6.990427965130048 -0.17266443245473528 QGSPDQVS(ph)PVSEMTSTSLYQDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QGSPDQVSPVSEMTSTSLYQDK 22 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QGS(0.019)PDQVS(0.979)PVS(0.001)EMTSTSLYQDK;QGS(0.023)PDQVS(0.806)PVS(0.083)EMT(0.002)S(0.033)T(0.033)S(0.009)LY(0.011)QDK;QGS(0.002)PDQVS(0.998)PVSEMTSTSLYQDK 90.193 0.00014184 16755900.0 122259.0 164707.0 155320.0 142405.0 150970.0 121003.0 153157.0 121276.0 119966.0 106358.0 True False 142955.03397468087 181058.0224493584 159023.41785438027 134426.50953323912 121388.51224721312 114657.38966639266 138648.86019934335 118092.63350254374 121720.27579662543 125639.86347053542 1.1378158971671133 1.4410873861847153 1.2657082987970123 1.0699351767822027 0.9661624017577883 0.9125876652459247 1.1035419521277874 0.9399296548124503 0.9688029932090049 1.0 16.938934754802233 -5.832143851957851 3.0191584921529206 0.9833218232937551 1.3042593327948875 0.7218397637086746 0.0830961492103291 0.12093352164227644 2.2247750544312015 0.023470910363562168 0.03891989394516819 1.4718249070978487e-06 5.832143851957851 0.3209375095011324 QGSPDQVS(ph)PVSEMTSTSLYQDK ddPTM_PC-9_Lapatinib_30min_R1 2 QGSPDQVSPVSEMTSTSLYQDK 22 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QGS(0.013)PDQVS(0.987)PVSEMTSTSLYQDK;QGS(0.05)PDQVS(0.946)PVS(0.003)EMTSTSLYQDK 86.304 0.00015524 10174400.0 46351.0 59460.0 69350.0 58796.0 78375.0 75010.0 70503.0 75121.0 71657.0 65566.0 True False 45690.02624026764 59322.324023211535 63648.310698741545 63120.053977706295 73765.13659117854 71801.9971568503 74153.30036617162 78611.39590269326 63586.23407833793 76898.99573879664 0.5941563449731291 0.7714317131619259 0.8276871510121694 0.8208176631084575 0.9592470731573283 0.9337182685810442 0.9642947824448664 1.0222681733024594 0.8268799022333365 1.0 16.230677137006793 -4.0486134560053975 0.5307360887428663 0.9618845064454242 5.4457104755183556e-18 0.7981239665745206 0.05554597956060378 3.609408376722302 0.4342585002252281 0.02970745620018725 2.5439509657174746 8.941009246106701e-05 4.0486134560053975 -0.9618845064454242 QGSPDQVS(ph)PVSEMTSTSLYQDKQEGK ddPTM_PC-9_AZD4547_30min_R2 4 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QGS(0.005)PDQVS(0.495)PVS(0.495)EMT(0.005)STSLYQDKQEGK;QGS(0.16)PDQVS(0.699)PVS(0.049)EMT(0.083)S(0.006)T(0.002)SLYQDKQEGK;QGSPDQVS(0.609)PVS(0.195)EMT(0.195)STSLYQDKQEGK;QGS(0.115)PDQVS(0.857)PVS(0.026)EMT(0.002)S(0.001)TSLYQDKQEGK 125.08 1.0944000000000001e-10 79803700.0 270114.0 173445.0 284468.0 517591.0 437907.0 328257.0 250681.0 316617.0 266749.0 352837.0 True False 356004.63327977323 229507.70434816257 280695.7684519108 398268.39165123436 377111.1718750373 307731.0378981557 272991.123366555 267691.1177848583 280848.8075611234 340484.2840252244 1.0455831589965516 0.674062548893328 0.8244015410447426 1.1697115266022942 1.1075729176595401 0.9038039414334842 0.8017730514290956 0.7862069714942458 0.824851015855748 1.0 18.37722868271193 -7.00368191724117 24.91520255046932 0.8378769195812601 0.9571773716876568 0.11439995544471793 0.1427639431982765 343.60040724336517 2325127.5235822327 0.05575627749383435 0.04812095993080075 9.915579085323495e-08 7.00368191724117 0.11930045210639673 QGSPDQVS(ph)PVSEMTSTSLYQDKQEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QGSPDQVS(0.478)PVS(0.478)EMT(0.018)S(0.018)T(0.005)S(0.001)LYQDKQEGK 80.868 4.3981000000000005e-05 14589000.0 54959.0 26548.0 45696.0 71588.0 74132.0 81903.0 74377.0 90521.0 75269.0 58108.0 True False 64262.47321027073 29183.509990380284 46785.565943045025 67577.1564514275 59606.366761014666 77607.86249800882 67331.4721171514 88144.9196649274 76369.66673004192 68642.52041732515 0.9361904664860046 0.42515207502512475 0.6815828681494116 0.9844795331025059 0.8683592385394142 1.130609162166208 0.9809003473036393 1.2841154306257072 1.112570841888353 1.0 16.066814906262465 -6.157316936014161 1.123344596405596 1.1166228788274253 0.6494046475235845 0.5485283709976061 0.1545075180521949 0.3466322808420654 0.9012110442238872 0.06239873361671201 0.10428872474174038 6.961183209428049e-07 6.157316936014161 -0.46721823130384077 QGSPDQVS(ph)PVSEMTSTSLYQDKQEGK ddPTM_PC-9_Lapatinib_30min_R1 4 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QGS(0.061)PDQVS(0.535)PVS(0.151)EMT(0.25)S(0.004)TSLYQDKQEGK;QGSPDQVS(0.478)PVS(0.478)EMT(0.032)S(0.011)T(0.001)SLYQDKQEGK;QGS(0.002)PDQVS(0.386)PVS(0.216)EMT(0.282)S(0.048)T(0.048)S(0.014)LY(0.003)QDKQEGK;QGS(0.366)PDQVS(0.617)PVS(0.017)EMTSTSLYQDKQEGK 142.54 6.439600000000001e-10 110665000.0 407933.0 218878.0 249846.0 232745.0 214112.0 229905.0 157784.0 157734.0 243479.0 155551.0 True False 402115.8006142492 218371.20143882462 229304.62631345025 249861.84371455936 201518.35312038806 220072.49908473092 165953.28347695866 165062.89747627737 216055.83107246537 182437.7830913206 2.2041256684914172 1.196962590416467 1.2568921986881967 1.369572900310289 1.104586723790195 1.2062879484485514 0.909643170756408 0.9047626795248542 1.1842713028600935 1.0 17.477045018816646 -2.626382870247983 1.1912251074734894 1.096589658701685 199.99999999999991 0.8306726072852069 0.14547163605327865 114.3924814965072 1.1830526158509123 0.04624827397343727 61097.17236843063 0.0023638348423336295 2.626382870247983 198.90341034129824 up QGSPDQVSPVS(ph)EMTSTSLYQDKQEGK ddPTM_PC-9_AZD4547_30min_R2 1 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QGS(0.001)PDQVS(0.162)PVS(0.819)EMT(0.017)S(0.002)TSLYQDKQEGK 115.84 1.6342e-11 26475000.0 141860.0 100450.0 169960.0 300880.0 243450.0 177350.0 128610.0 179690.0 154750.0 204500.0 True False 186968.52912869572 132918.49809318778 167706.2193501086 231516.76454966087 209651.16975288786 166260.27646398416 140056.040849417 151923.03936541965 162929.7690716136 197340.51724495564 0.9474411628130814 0.6735489495459169 0.8498316599724806 1.1731841376613137 1.062382792341885 0.8425045134426598 0.7097176130108531 0.7698522406163556 0.825627556602436 1.0 17.5903276698656 -6.984869816112879 24.51157568109544 0.8026904505473204 0.9360309373644822 0.12805690902776812 0.1406567452912608 381.12759842057335 617440.7252174406 0.05419338658038436 0.047776390123654006 1.0354525068660921e-07 6.984869816112879 0.13334048681716182 QGSPDQVSPVS(ph)EMTSTSLYQDKQEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QGSPDQVS(0.024)PVS(0.855)EMT(0.057)S(0.055)T(0.008)S(0.001)LYQDKQEGK;QGSPDQVS(0.057)PVS(0.931)EMT(0.012)STSLYQDKQEGK 125.79 1.6163999999999997e-10 42278000.0 132748.0 69620.0 97312.0 162100.0 160156.0 190227.0 158483.0 203055.0 178566.0 135097.0 True False 155219.61450748803 76531.413497449 99632.28713781503 153018.06253529107 128774.58148946588 180251.1612445055 143470.3429224426 197725.02140455594 181177.1899363173 159589.0166727365 0.9726209092809398 0.47955313650681386 0.6243054140882853 0.9588257746401166 0.8069138100746577 1.1294709686327606 0.8989988528888057 1.2389638430445598 1.1352735527398536 1.0 17.2840018394242 -6.412275904879881 1.0578188982997883 1.102416552458298 0.6821133525817732 0.488389604061943 0.1594732591805966 0.4038317043086777 0.9582463714223189 0.07363462418479037 0.09553480958703504 3.8701170041571413e-07 6.412275904879881 -0.42030319987652487 QGSPDQVSPVS(ph)EMTSTSLYQDKQEGK ddPTM_PC-9_Lapatinib_30min_R1 6 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QGSPDQVS(0.101)PVS(0.882)EMT(0.016)S(0.001)TSLYQDKQEGK;QGSPDQVS(0.208)PVS(0.789)EMT(0.002)STSLYQDKQEGK;QGSPDQVS(0.006)PVS(0.766)EMT(0.043)S(0.148)T(0.03)S(0.006)LYQDKQEGK;QGSPDQVS(0.002)PVS(0.975)EMT(0.023)STSLYQDKQEGK;QGS(0.001)PDQVS(0.033)PVS(0.658)EMT(0.149)S(0.111)T(0.036)S(0.012)LY(0.001)QDKQEGK;QGSPDQVS(0.015)PVS(0.984)EMT(0.001)STSLYQDKQEGK 126.86 5.765e-12 50155600.0 383253.0 195804.0 237065.0 210416.0 203612.0 218340.0 147666.0 145234.2 252175.0 160589.0 True False 377787.7419400067 195350.62786816168 217574.4307973636 225890.6945671994 191635.94247659427 209002.10717539905 155311.42294471286 151982.311135514 223772.3959795254 188346.5946786082 2.0058113744220223 1.0371869382693382 1.155181123229912 1.1993351669174368 1.0174643337916407 1.1096675654372041 0.824604358840328 0.8069289035719193 1.1880883557325115 1.0 17.523030423916985 -4.761425576748825 11.063237868143279 1.0351279367643833 2.008039742176805 0.8337078525503202 0.1297192374761468 0.02685196670402471 113.90027240582351 0.034683954351018204 0.19490468375533876 1.7321058291389713e-05 4.761425576748825 0.9729118054124217 QGSPDQVSPVSEMT(ph)STSLYQDKQEGK ddPTM_PC-9_AZD4547_30min_R2 3 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QGS(0.016)PDQVS(0.063)PVS(0.326)EMT(0.551)S(0.033)T(0.011)SLYQDKQEGK;QGSPDQVS(0.069)PVS(0.35)EMT(0.546)S(0.032)T(0.002)SLYQDKQEGK;QGS(0.025)PDQVS(0.258)PVS(0.068)EMT(0.617)S(0.027)T(0.005)SLYQDKQEGK 120.33 3.5293e-12 154183000.0 193664.0 138218.0 209692.0 362980.0 330690.0 245527.0 196168.0 219894.0 183865.0 270633.0 True False 255245.12353855727 182894.26549969372 206911.34706968113 279300.56898509694 284779.40162490174 230174.15787636058 213626.5719722293 185914.43496143154 193583.72853216296 261158.2210442744 0.9773581797192795 0.7003197707825077 0.7922834909899438 1.0694687989077198 1.090447777160432 0.8813590357446145 0.8179967343858304 0.7118842907492209 0.7412507550330745 1.0 17.99456459370557 -11.03832947369929 6.534714555240629 1.0000920144396641 0.8650254823276308 0.08431377037184573 0.13375394577345742 0.00019880101435634334 1.474111615865854e-05 0.14358704677435544 0.034801315769811714 9.155256710762902e-12 11.03832947369929 -0.13506653211203334 QGSPDQVSPVSEMT(ph)STSLYQDKQEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QGS(0.011)PDQVS(0.103)PVS(0.293)EMT(0.432)S(0.116)T(0.033)S(0.01)LY(0.001)QDKQEGK;QGSPDQVS(0.336)PVS(0.232)EMT(0.41)S(0.022)TSLYQDKQEGK;QGS(0.171)PDQVS(0.22)PVS(0.069)EMT(0.506)S(0.032)T(0.002)SLYQDKQEGK;QGSPDQVS(0.027)PVS(0.145)EMT(0.818)S(0.008)T(0.002)SLYQDKQEGK 135.33 5.2371e-12 144242000.0 293459.0 147051.0 218787.0 381871.0 399950.0 472781.0 370367.0 478494.0 395504.0 323621.0 True False 343135.8126205498 161649.25145379768 224003.71183431792 360476.0059124853 321582.6685650981 447987.53207661625 335283.15653512493 465934.0395063013 401287.49777994363 382290.9255175739 0.8975777077522492 0.422843548365541 0.5859508999096565 0.942936339449978 0.8411988020111006 1.1718497672161519 0.8770366601854168 1.2187944008231038 1.049691402527148 1.0 18.54431142960238 -6.059329198246876 1.5873068574757117 1.0549507517833232 0.6148333976541852 0.5503152274444896 0.1558404797368702 0.2655632069403172 1.3435651931958164 0.052204427961883695 0.08433030361482234 8.723099007313369e-07 6.059329198246876 -0.440117354129138 QGSPDQVSPVSEMT(ph)STSLYQDKQEGK ddPTM_PC-9_Lapatinib_30min_R1 3 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QGSPDQVS(0.104)PVS(0.104)EMT(0.606)S(0.145)T(0.036)S(0.004)LYQDKQEGK;QGSPDQVS(0.154)PVS(0.154)EMT(0.499)S(0.123)T(0.032)S(0.032)LY(0.005)QDKQEGK;QGS(0.032)PDQVS(0.057)PVS(0.02)EMT(0.868)S(0.02)T(0.002)SLYQDKQEGK 125.35 5.5013999999999995e-11 105912000.0 275710.0 133048.0 162255.0 148282.0 141236.0 144318.0 101035.0 93735.0 153454.0 108947.0 True False 271778.3248409789 132739.93553044452 148915.02022241277 159187.152934251 132928.77616065956 138145.8555616894 106266.09793194817 98090.27029644113 136170.39457774215 127778.34378724736 2.126951381475827 1.0388296764235596 1.1654167350169937 1.2458069827489682 1.0403075530700863 1.0811366892632768 0.8316440390625397 0.7676595844735844 1.0656766283061836 1.0 16.96328381965605 -2.9848728374227504 1.460330532715453 1.0061798953156318 199.9999994260467 0.8395956392290572 0.14263067252177172 102.23071099139642 1.6094915972222141 0.04435228916182367 66938.87529166434 0.0010354453034312602 2.9848728374227504 198.9938195307311 up QGSPS(ph)QSLVACECEASK ddPTM_PC-9_AZD4547_30min_R2 1 QGSPSQSLVACECEASK 17 0 Q4AC94 Q4AC94 C2CD3 C2 domain-containing protein 3 1 QGS(0.284)PS(0.716)QSLVACECEASK 132.74 1.6031e-05 0.0 6381.7 5233.6 8732.1 13617.0 10110.0 7076.3 9296.2 12123.0 6607.6 8296.1 True False 8410.947852393907 6925.2588513738965 8616.306648547215 10477.811030552817 8706.401011302903 6633.817842357426 10123.54379087433 10249.668908826245 6956.864246317242 8005.656064136313 1.0506256807700267 0.8650457621328035 1.0762773943220583 1.3088010459868802 1.0875312331122722 0.8286413741998687 1.264548927629519 1.2803034288148658 0.868993645315661 1.0 12.966803921218986 -5.496838199025044 22.456526981293397 1.1062523440663368 0.9610419604047774 0.09228090171624481 0.1608159381099988 442.61535920343266 381692.8897490468 0.04258384836333686 0.08794599594811635 3.1853840490010843e-06 5.496838199025044 -0.14521038366155936 QGSVVS(ph)SR ddPTM_PC-9_AZD4547_30min_R2 1 QGSVVSSR 8 0 Q9BZ67-2;Q9BZ67-3;Q9BZ67 Q9BZ67-2 FRMD8 FERM domain-containing protein 8 1 QGS(0.193)VVS(0.807)SR 107.55 0.0038082 11182000.0 26355.0 33718.0 36414.0 51927.0 56398.0 39488.0 28826.0 47329.0 43333.0 42634.0 True False 34735.341781945506 44616.68410857249 35931.126567515086 39956.03241415261 48568.11120034238 37018.80911761938 31391.45815663857 40015.39056222362 45623.49391392719 41141.396636779646 0.8442917504383591 1.0844717913316049 0.87335699574655 0.9711880412545999 1.180516831480713 0.8997946628901083 0.7630139159781267 0.9726308252367544 1.1089437317045439 1.0 15.328303149755394 -5.599480432901789 0.005389566395310719 1.9213366117398822 1.2470657425185357e-07 0.02001633059894503 0.12146420233707096 147455.61845100412 166.1778892179946 28765.62758815098 30486.519405597646 2.51489331873185e-06 5.599480432901789 -1.921336487033308 QGSVVS(ph)SR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QGSVVSSR 8 0 Q9BZ67-2;Q9BZ67-3;Q9BZ67 Q9BZ67-2 FRMD8 FERM domain-containing protein 8 1 QGS(0.376)VVS(0.624)SR 86.882 0.012143000000000001 8342400.0 25161.0 29211.0 31813.0 32379.0 41773.0 39530.0 37478.0 36581.0 33713.0 25470.0 True False 29420.260347597683 32110.875031226402 32571.54257147434 30564.909604134347 33587.880519989565 37456.97721141214 33927.81252277723 35620.78751077334 34205.98884627013 30087.50937959092 0.9778230552893206 1.0672493567383141 1.082560279767404 1.0158670569411525 1.1163396775797279 1.24493445897586 1.127637787984913 1.183906153924983 1.13688336295037 1.0 14.876877066000354 -6.429035440622988 5.091338163732999 1.152513631358995 1.0424298460981227 0.35699490883543117 0.06394967163682426 0.22376921161417718 9.282436440550894 0.019210378196470652 0.021671840749965532 3.7236131845060977e-07 6.429035440622988 -0.11008378526087226 QGSVVS(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 1 QGSVVSSR 8 0 Q9BZ67-2;Q9BZ67-3;Q9BZ67 Q9BZ67-2 FRMD8 FERM domain-containing protein 8 1 QGS(0.008)VVS(0.992)SR 107.55 0.0038082 8407000.0 41389.0 23305.0 30449.0 27688.0 35302.0 27570.0 30888.0 34666.0 40867.0 39002.0 True False 40798.785270186985 23251.03870435493 27945.600756539 29724.267884460354 33225.60576640239 26390.895368809004 32487.229503855255 36276.708914454895 36264.1281114118 45743.44373310172 0.8919045428287992 0.5082922667566803 0.6109203522059378 0.6498038944748431 0.7263468391287529 0.5769328501542514 0.7102051540633405 0.7930471769051282 0.7927721472611753 1.0 15.48127736072643 -8.487923342064843 0.8136137348614293 0.9966534471692801 0.6506937265038382 0.5167493067221139 0.09842639642213011 0.5001674085307346 0.7438758982859264 0.091224208127248 0.03352204647857735 3.251446840700681e-09 8.487923342064843 -0.3459597206654419 QGSYS(ph)PALPLQPLGGHK ddPTM_PC-9_Lapatinib_30min_R1 1 QGSYSPALPLQPLGGHK 17 0 H3BMJ2;Q6ZRI6-2;Q6ZRI6 H3BMJ2 C15orf39 Uncharacterized protein C15orf39 1 QGS(0.026)YS(0.974)PALPLQPLGGHK 100.94 0.0031723000000000003 0.0 30124.0 22861.0 27461.0 22105.0 21185.0 21246.0 22738.0 15725.0 23424.0 19358.0 True False 29694.42623593496 22808.066759075653 25203.26258252547 23730.67544011834 19938.93995131253 20337.358106844982 23915.262382111523 16455.640906934845 20785.74245434483 22704.00450708636 1.307893778239286 1.0045834316125515 1.110080055465944 1.0452198171785747 0.8782124732704841 0.8957608381595105 1.0533499662866568 0.7247902413778469 0.9155099686426329 1.0 14.470659160457243 -1.5228787452805266 0.4306069657556628 0.8931220357142153 8.37415016364577 0.5614564708625548 0.09822132276090835 59.651227588883195 0.7487942112750253 0.06403497424894734 387.312339216788 0.029999999999986943 1.5228787452805266 7.481028127931554 QGVCCADRR ddPTM_PC-9_AZD4547_30min_R2 1 QGVCCADRR 9 1 K7EQ05;P28799-3;P28799-2;P28799 K7EQ05 GRN Granulins;Acrogranin;Paragranulin;Granulin-1;Granulin-2;Granulin-3;Granulin-4;Granulin-5;Granulin-6;Granulin-7 0 83.647 0.008867299999999998 1446800.0 2461.1 2427.9 4917.5 4408.1 4096.2 3390.5 2766.8 2747.5 2808.9 3442.1 False True 3243.6786059399 3212.6711948277807 4852.290736962577 3391.880649466097 3527.5133355587495 3178.4914990196658 3013.039839998184 2322.9370062690828 2957.372719516995 3321.5931266936996 0.9765430268603201 0.9672079247182392 1.460832363231835 1.0211607864333345 1.0619944108175652 0.9569177734250442 0.907106838517983 0.6993442356322928 0.8903476755627658 1.0 11.69765964813358 -6.888618135314215 1.6304043680368452 0.846487230870449 1.117509225012605 0.3390324067889908 0.14787716553427163 0.40716077515730364 2.2249426938374874 0.06950190946957342 0.05714907942471155 1.292355110929115e-07 6.888618135314215 0.2710219941421561 QGVCCADRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QGVCCADRR 9 1 K7EQ05;P28799-3;P28799-2;P28799 K7EQ05 GRN Granulins;Acrogranin;Paragranulin;Granulin-1;Granulin-2;Granulin-3;Granulin-4;Granulin-5;Granulin-6;Granulin-7 0 ; 66.568 0.030432999999999998 1712340.0 5873.5 5060.2 5185.700000000001 6544.6 9935.5 7598.2 7574.3 6213.4 7897.0 5788.1 False True 6867.767543087119 5562.543214303239 5309.346754876769 6177.927279879483 7988.710097583522 7199.737016133361 6856.807470816787 6050.30483364148 8012.47868534379 6837.436711425607 1.0044359945022712 0.8135421867975795 0.7765112832422502 0.9035443457276818 1.168377922128931 1.0529877379489796 1.0028330440497988 0.8848790985562176 1.1718541645810987 1.0 12.739239858777886 -6.021961383296207 20.862609869203286 1.0388828141526574 0.8564221422396331 0.4401738304558134 0.09555650261013049 85.13456021533491 80875.9009911373 0.028233449101901936 0.036936780405932484 9.506893235257099e-07 6.021961383296207 -0.18246067191302429 QGVCCADRR ddPTM_PC-9_Lapatinib_30min_R1 1 QGVCCADRR 9 1 K7EQ05;P28799-3;P28799-2;P28799 K7EQ05 GRN Granulins;Acrogranin;Paragranulin;Granulin-1;Granulin-2;Granulin-3;Granulin-4;Granulin-5;Granulin-6;Granulin-7 0 68.016 0.027964999999999997 1663700.0 7415.6 7034.1 4950.9 4416.9 4100.6 4308.3 5598.9 3037.3 5031.4 4596.6 False True 7309.852184145509 7017.812973623817 4543.856113026665 4741.7335603464635 3859.4107700897857 4124.044052137827 5888.783646371903 3178.4240462087896 4464.710749009161 5391.1161854155 1.355907001952719 1.3017365481027832 0.8428414370514007 0.8795457929796059 0.7158834344046577 0.7649703531329073 1.0923125089202743 0.5895669721990651 0.8281607361917874 1.0 12.396368286480502 -5.249448145753679 4.382923354439546 0.8256489222489983 1.3434911191425478 0.6852282682857841 0.1327457121359277 0.10250751366421097 5.112456792711271 0.03394554911541375 0.08878477275299211 5.6305634164065404e-06 5.249448145753679 0.5178421968935495 QGVLTHGR ddPTM_PC-9_AZD4547_30min_R2 4 QGVLTHGR 8 0 P62753;A2A3R5 P62753 RPS6 40S ribosomal protein S6 0 ;;; 132.76 0.0030697 14186400.0 104417.0 100575.0 137723.0 159390.0 144718.0 139782.0 121529.0 151924.0 123149.0 138081.0 False True 137619.43399147794 133083.90189867964 135896.70303339043 122645.0980509519 124626.40371451392 131041.40944284527 132344.84556713136 128447.63666621472 129658.4047263337 133246.82621858566 1.0328158493300186 0.9987772742921566 1.0198869788497458 0.9204354169738941 0.9353048567931344 0.9834486356011024 0.9932307532040228 0.9639827102185677 0.9730693661223472 1.0 17.023741644545183 -5.719954214408134 24.999996536108547 0.9660158792716491 1.0153218523042753 0.4719978746376171 0.02423780284149626 139.05734919231793 83798.39336190876 0.006932165636012981 0.012006738069051195 1.9056616121705961e-06 5.719954214408134 0.04930597303262618 QGVLTHGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QGVLTHGR 8 0 P62753;A2A3R5 P62753 RPS6 40S ribosomal protein S6 0 ;; 127.46 0.0030328000000000004 6044280.0 36459.4 31822.9 42051.0 38637.0 48864.0 40813.0 40647.0 37496.7 40869.0 31339.1 False True 42631.25631402579 34982.06720178066 43053.65531930555 36472.29415284411 39289.449973159 38672.694432819735 36796.62190120405 36512.45135603769 41466.631808448205 37020.63074982092 1.1515540240824236 0.9449343918039504 1.1629638514334015 0.9851883507689975 1.0612852665496266 1.0446254871820844 0.9939490807131115 0.9862730757555855 1.120095227136258 1.0 15.176041855305927 QGVLTHGR ddPTM_PC-9_Lapatinib_30min_R1 3 QGVLTHGR 8 0 P62753;A2A3R5 P62753 RPS6 40S ribosomal protein S6 0 ;; 120.87 0.0028511 15671000.0 73872.0 66687.0 70317.0 71910.0 79506.0 71868.0 67100.0 63382.0 74968.0 64560.0 False True 72818.57173353447 66532.59034873717 64535.807691469505 77198.50128472778 74829.61339481015 68794.37317249057 70574.10967717848 66326.95910736693 66524.31439196221 75719.10997920747 0.9616934450699501 0.8786763389982671 0.8523054181327685 1.0195378855605481 0.9882526804047014 0.9085470390682294 0.9320514952771921 0.8759606277144616 0.878567040872903 1.0 16.208369832903138 -5.334190029717351 0.0032821481722291592 1.8422023824879499 5.526971806808258e-08 0.02862959441972812 0.05576469465019938 358488.5041600097 221.82771798280854 61033.57779217608 63487.11544868414 4.632441784489958e-06 5.334190029717351 -1.8422023272182317 QGVSYSVHAYTGQPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 QGVSYSVHAYTGQPSPR 17 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 QGVSYSVHAYTGQPS(1)PR;QGVSYSVHAYTGQPS(1)PR 201.61 7.3582e-13 7425800.0 1328.6 1626.72 10470.3 22946.7 14207.9 8982.2 3553.2 14483.4 7698.599999999999 10104.9 True False 1751.0671634032537 2152.5254277565987 10331.456980827517 17656.69283798092 12235.378331205795 8420.541614067086 3869.4279165395205 12245.323325422256 8105.532278996604 9751.130526692186 0.179575810067354 0.22074624289608255 1.0595137612553518 1.8107328980622812 1.2547651062318745 0.8635451644316705 0.39681839002642516 1.255784987381987 0.8312402604814881 1.0 13.251353776416746 -5.259446696660671 7.134061379131928 1.072188838464789 0.19581435953413864 0.5007745035284457 0.34290648570052495 0.1072511222381458 40.646127297991406 0.09754259437246501 0.23208863164814697 5.502414505120102e-06 5.259446696660671 -0.8763744789306505 QGY(ph)WLPS(ph)Y(ph)KLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QGYWLPSYKLK 11 1 Q9Y574-2;Q9Y574 Q9Y574-2 ASB4 Ankyrin repeat and SOCS box protein 4 3 QGY(1)WLPS(1)Y(1)KLK 64.53399999999999 0.017667 22582000.0 20575.0 23795.0 19209.0 24877.0 29785.0 21581.0 29468.0 25116.0 21825.0 18327.0 True False 24057.94112522642 26157.21034432347 19667.01541053817 23483.222342322188 23948.843063411514 20449.254368820784 26676.577710155278 24456.731612601692 22144.149336156537 21649.540023547834 1.1112449086243408 1.2082109049833263 0.9084264787679874 1.0846984424047759 1.106205630113285 0.9445583761400234 1.2322006694433056 1.1296651839254102 1.0228461811230505 1.0 14.4020487526402 -7.256396075924884 24.938878960942013 1.1069834367326647 1.0635261766365478 0.025019080439636854 0.09920088688708349 1601.9639598613676 7921652.075367345 0.03874378216039968 0.029127181354840232 5.5412012571080926e-08 7.256396075924884 -0.043457260096116945 QHAADTSEARPFR ddPTM_PC-9_AZD4547_30min_R2 1 QHAADTSEARPFR 13 1 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;Q9NUQ6-2 B8ZZZ7 SPATS2L SPATS2-like protein 0 66.393 0.016916 926280.0 2861.2 2838.5 4570.2 8020.7 5085.7 4159.9 2696.0 4739.2 2734.5 3468.7 False True 3771.002083342913 3755.9896151071525 4509.596161884369 6171.651533579717 4379.638340572024 3899.7807953906204 2935.9387771559573 4006.8655359819613 2879.0400874076063 3347.2618687901104 1.1265930874736032 1.122108087845777 1.3472492857316813 1.8437910672971938 1.3084241724281565 1.1650659399410006 0.8771165484632881 1.1970576826814776 0.8601179711249345 1.0 11.708765707519886 -6.9150698429503175 3.1996886701316187 1.0009555789246662 1.3647336251231215 0.41065301503986984 0.20571188928663361 0.281246064538733 5.778045348530214 0.0850537857463342 0.07291746019386423 1.215990430147166e-07 6.9150698429503175 0.3637780461984552 QHAADTSEARPFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QHAADTSEARPFR 13 1 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;Q9NUQ6-2 B8ZZZ7 SPATS2L SPATS2-like protein 0 78.903 0.0065227 933400.0 1190.3 869.39 2820.7 2964.0 3347.9 3051.9 2290.2 2557.6 2390.5 2376.7 False True 1391.794280503379 955.697293601654 2887.9561855643187 2797.936689417654 2691.903028101241 2891.8529914371024 2073.2556763878633 2490.465710001198 2425.456540118316 2807.576896053152 0.4957279291120902 0.3403993297370264 1.0286294169268035 0.9965663606047444 0.9587993945545985 1.0300173774411752 0.7384501843217238 0.8870516470990542 0.8638967443876551 1.0 11.455109821459045 -5.2602195384543515 24.999821809472696 0.9328970897025906 0.4180635917080925 0.8363671272705352 0.09195679674654518 39.42583156003805 807982.5516792526 0.024887866665718662 0.0588175234252496 5.492631478658386e-06 5.2602195384543515 -0.5148334979944981 QHEAPSNRPLNELLTPQGPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 QHEAPSNRPLNELLTPQGPSPR 22 1 Q96II5;P10398 Q96II5 ARAF Serine/threonine-protein kinase A-Raf 1 QHEAPSNRPLNELLT(0.027)PQGPS(0.973)PR;QHEAPSNRPLNELLT(0.002)PQGPS(0.998)PR 60.943000000000005 0.0032323 11215700.0 25489.6 33220.6 55691.6 72933.3 59244.7 54801.0 45506.5 57641.6 48241.5 57144.9 True False 33594.7625833837 43958.50928575962 54953.09299575497 56119.65449325232 51019.59604296114 51374.28480689476 49556.49034222829 48734.41519219651 50791.447203025804 55144.274444553856 0.6092157875277218 0.7971545501058095 0.9965330680161344 1.017687784607252 0.9252020550974884 0.9316340694363523 0.8986697321052988 0.8837620166930967 0.9210647472403557 1.0 15.75092348006678 -4.923194056770656 2.8789239403915188 0.941535071842396 0.5961114474681186 0.8522921503658218 0.04392285313483635 0.12249727122738155 1.7513191003468513 0.012657593438531112 0.08555764379892204 1.193454711277684e-05 4.923194056770656 -0.3454236243742774 QHEAPSNRPLNELLTPQGPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 QHEAPSNRPLNELLTPQGPSPR 22 1 Q96II5;P10398 Q96II5 ARAF Serine/threonine-protein kinase A-Raf 1 QHEAPS(0.003)NRPLNELLT(0.117)PQGPS(0.88)PR 44.729 0.032793 5175700.0 3452.0 4684.0 4845.1 5136.7 4911.6 4807.2 4221.0 4155.2 3794.3 4193.2 True False 3402.7738469807314 4673.1544857841045 4446.75458062686 5514.4700535288775 4622.709344577132 4601.607262130528 4439.542726488383 4348.26576130338 3366.9459782496815 4917.989032912207 0.691903504503296 0.9502165325116386 0.904181475572282 1.1212855532261041 0.9399592625443037 0.9356684676064981 0.9027150521845491 0.8841552374769198 0.6846184397153751 1.0 12.263852802397869 -7.864271617135096 3.3566047696231993 0.8283713747207624 0.9311255998295918 0.05256855788072623 0.12091071698405896 0.563671229153702 12.262041374200853 0.07498703314592352 0.03253326009136315 1.3668736859307745e-08 7.864271617135096 0.10275422510882937 QHEEFDLS(ph)PDQWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QHEEFDLSPDQWR 13 0 Q86US8 Q86US8 SMG6 Telomerase-binding protein EST1A 1 QHEEFDLS(1)PDQWR 87.13799999999999 0.030833999999999997 0.0 3979.7 3654.7 4585.8 4966.7 5837.7 4717.2 5369.7 3095.8 4592.9 3752.7 True False 4653.384607342097 4017.514462929143 4695.14286374335 4688.431901258657 4693.844591280091 4469.821727844 4861.04314273859 3014.538530271235 4660.062473586865 4433.034803643146 1.0497063103402355 0.9062672956295039 1.0591261002247938 1.0576122473492924 1.0588332370913502 1.0082983612424206 1.0965497358025926 0.680016887707228 1.0512126973957308 1.0 12.114078973771687 QHFISFDTDR ddPTM_PC-9_AZD4547_30min_R2 3 QHFISFDTDR 10 0 C9J0K6;P30626-3;P30626-2;P30626 C9J0K6 SRI Sorcin 0 ;; 120.63 0.00057903 18098700.0 19698.5 25345.2 31862.0 43716.0 36919.0 32631.800000000003 28989.699999999997 34563.0 28813.699999999997 31261.4 False True 25962.213245746665 33537.540247600446 31439.48906173905 33637.9516054672 31793.43411832758 30591.328387467885 31569.72713950967 29222.08252872733 30336.73335766559 30166.947901229603 0.860617830174608 1.1117313013370325 1.0421832916169016 1.1150598236056926 1.0539161675361821 1.0140677302731373 1.046500535714549 0.968678787937186 1.005628194704744 1.0 14.88068112076396 -7.749773024227321 24.799894095975443 0.9903651179044067 1.0411226362851909 0.07605495265430051 0.06689996822525748 443.84674405643653 943516.9404597424 0.030902091324137865 0.01764484504195944 1.7792090369445345e-08 7.749773024227321 0.05075751838078413 QHFISFDTDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QHFISFDTDR 10 0 C9J0K6;P30626-3;P30626-2;P30626 C9J0K6 SRI Sorcin 0 ; 120.63 0.00057903 11205600.0 16152.2 18566.0 17492.1 21611.8 24361.0 21996.0 17955.5 14890.2 17140.7 17350.8 False True 18886.448439508258 20409.109781580562 17909.178003158664 20400.960912400966 19587.636926901738 20842.491038255037 16254.625053437385 14499.34802747102 17391.350310481495 20496.36269114278 0.9214536610278553 0.995743005191847 0.8737734725438806 0.9953454288363545 0.9556640474246811 1.0168873059248622 0.7930492496828033 0.7074107853163973 0.8485091024465979 1.0 14.323080289619723 -7.270829674616543 24.702315265858022 0.8128598396746205 0.9589603056863315 0.3500901098308308 0.0790639429552641 527.8654166924354 1388607.983680651 0.031296616414536606 0.021415225864464545 5.360068321133287e-08 7.270829674616543 0.146100466011711 QHFISFDTDR ddPTM_PC-9_Lapatinib_30min_R1 2 QHFISFDTDR 10 0 C9J0K6;P30626-3;P30626-2;P30626 C9J0K6 SRI Sorcin 0 ; 149.33 0.00010432 10011100.0 14730.6 16300.7 18615.6 15401.7 14999.2 18846.4 19743.9 18732.3 18904.1 14638.7 False True 14520.5389427388 16262.95673066203 17085.097226294063 16534.39239656505 14116.976545561793 18040.383405104174 20766.142534355356 19602.671043623253 16774.921189001874 17168.979790158348 0.8457426777951189 0.9472290683214811 0.9951142953810006 0.9630387244117407 0.822237355865138 1.050754536704932 1.2095152296852831 1.1417493225112858 0.9770482226682824 1.0 14.067516694055 -6.945115587108633 7.926797343017086 1.0990169643713827 0.9242819279445935 0.506762055667455 0.07897016501982944 0.19907650001169291 25.156369535669246 0.028300859347721266 0.024915016763773435 1.1347087737006495e-07 6.945115587108633 -0.17473503642678923 QHIPYREDK ddPTM_PC-9_AZD4547_30min_R2 1 QHIPYREDK 9 1 U3KPX3;A0A590UJ43;P48729;P48729-2;A0A5F9W493;P48729-3;U3KQ83;D6REM4;E7ETM0;Q8N752 U3KPX3 CSNK1A1;CSNK1A1L Casein kinase I isoform alpha;Casein kinase I isoform alpha-like 0 70.816 0.016515000000000002 2618700.0 20236.0 15682.0 22326.0 22269.0 21004.0 22695.0 20833.0 23825.0 18537.0 23631.0 False True 26670.627065052115 20750.899821775725 22029.942652450754 17135.226102620294 18087.957155430886 21275.878062306823 22687.096641131335 20143.3936940349 19516.82797596447 22803.6858827166 1.1695752696394732 0.9099800764008626 0.9660693786852992 0.7514235282291556 0.7932032237446375 0.933001716114335 0.9948872633053751 0.883339377574132 0.8558628669217325 1.0 14.47697941336652 -4.502761781952548 1.9736702822646874 0.888731710492219 1.4806380459306328 0.5152477061487745 0.07824960614678349 1.795234741379859 3.759281387644883 0.021982313267351082 2.5205025241985517 3.142231789834742e-05 4.502761781952548 0.5919063354384138 QHIPYREDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QHIPYREDK 9 1 U3KPX3;A0A590UJ43;P48729;P48729-2;A0A5F9W493;P48729-3;U3KQ83;D6REM4;E7ETM0;Q8N752 U3KPX3 CSNK1A1;CSNK1A1L Casein kinase I isoform alpha;Casein kinase I isoform alpha-like 0 63.419 0.025939 2330200.0 19665.0 15945.0 13815.0 21693.0 23285.0 20747.0 23571.0 16345.0 18755.0 13884.0 False True 22993.896098545705 17527.914223166106 14144.40199367926 20477.611539654914 18722.471402771105 19658.990796993876 21338.184240738086 15915.961068959028 19029.25639402592 16401.059294316467 1.4019762800634399 1.0687062285812317 0.8624078323148787 1.2485542044684341 1.1415403765572074 1.1986415294411132 1.3010247605246146 0.9704227503448182 1.1602455702736356 1.0 14.001501376667443 -8.531363024245051 1.1491263152437947 1.0095333555825359 1.1528429561423839 0.08557063926676467 0.14828976748584968 1.5115538227158922 4.373359795484629 0.14298022377269684 0.04530281565367253 2.941961437163717e-09 8.531363024245051 0.14330960055984798 QHLVEVR ddPTM_PC-9_AZD4547_30min_R2 2 QHLVEVR 7 0 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2;A0A2R8Y5T0 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ; 122.74 0.00010668 1575200.0 20607.0 21415.3 24743.0 33961.0 29839.0 28565.0 24414.0 26548.0 24844.0 27706.0 False True 27159.597347772757 28337.37692598352 24414.891653210994 26131.816142219606 25696.369908631783 26778.826034359736 26586.79870381511 22445.61661234999 26157.20311996875 26736.021373050084 1.0158428948276366 1.0598950580787463 0.9131834281753385 0.9774010791508598 0.9611142043196349 1.001601010887611 0.9944186658458694 0.8395271794245039 0.9783506212459577 1.0 14.706497171366882 -5.252340788262524 24.944130483668282 0.9561018106305837 1.0378689815828344 0.3070355968125025 0.04779239894566194 758.8004211081967 2080269.0789895542 0.012294750277180294 0.03149674848383208 5.5931853536759075e-06 5.252340788262524 0.08176717095225061 QHLVEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QHLVEVR 7 0 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2;A0A2R8Y5T0 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 75.738 0.027092 1518800.0 12061.0 11112.0 8901.0 13939.0 17080.0 10030.0 14491.0 8812.6 10418.0 9944.7 False True 14102.68908439154 12215.125923350372 9113.233597230485 13158.043020847726 13733.296609805897 9504.009143194125 13118.307574245284 8581.278587721525 10570.34354108036 11747.595387798123 1.2004745327745612 1.0397979773833426 0.7757531049031642 1.1200626669960556 1.169030440397212 0.8090174056441931 1.1166802346521807 0.730471071265754 0.8997878452691229 1.0 13.520077861691083 -7.243344180949129 1.4270196655866065 0.8864604464977279 1.036756693968543 0.12713832937343805 0.15234453052832775 0.8752023314058079 3.484718264998005 0.09121478929220435 0.05453223700758288 5.7102591588322355e-08 7.243344180949129 0.15029624747081516 QHPEESSER ddPTM_PC-9_Lapatinib_30min_R1 2 QHPEESSER 9 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 0 ; 99.44200000000001 0.0034744999999999997 456470.0 2382.3599999999997 1936.27 507.3 1134.6 2179.69 0.0 2932.7599999999998 6043.0 2035.75 1601.6 False True 2348.3871095286827 1931.7866857790732 465.5917522346295 1218.0422689146467 2051.4849196354207 0.0 3084.60396269511 6323.779841056105 1806.462397602137 1878.4344260021453 1.250183172231747 1.0284025138372688 0.2478615946288549 0.6484348093571702 1.0921248520777898 0.0 1.6421142628119547 3.3665161548997737 0.961685099355219 1.0 10.875315038686624 -7.506175782339004 24.445868098184057 1.9993232411779278 0.7274981459793346 0.31689595498309453 0.721582137536482 522.0764596922162 764096.7503898246 0.2944801464386312 0.1927037220870607 3.1176274571461374e-08 7.506175782339004 -1.2718250951985932 QHS(ph)PIQVPMVAGSPLGATQTCNK ddPTM_PC-9_Lapatinib_30min_R1 1 QHSPIQVPMVAGSPLGATQTCNK 23 0 C9JGM9;C9JF73;C9JTM8;E9PJI6;C9J811;Q8N9N5-3;Q8N9N5-6;Q8N9N5-2;Q8N9N5-4;Q8N9N5-5;Q8N9N5-7;Q8N9N5 C9JGM9 BANP Protein BANP 1 QHS(1)PIQVPMVAGSPLGATQTCNK 59.618 0.0033090000000000003 4346100.0 10308.0 14555.0 12710.0 12295.0 11928.0 8981.1 10970.0 10892.0 12560.0 8326.4 True False 10161.006029744307 14521.29879175654 11665.032862018807 13199.215314917661 11226.418491350287 8596.99928896665 11537.97292337776 11398.082083200916 11145.360537336537 9765.60714576939 1.040488919743839 1.486983714888366 1.1945015489459123 1.3516021193455199 1.1495873552740385 0.8803343366818724 1.1814905874414767 1.1671657392176316 1.1412870056077238 1.0 13.253494026568426 -6.5116118790044055 24.32093719531997 1.0827450703089552 1.2752127587854185 0.31631386414859197 0.13431805116710643 459.15821883105366 991153.331087945 0.0416252979477925 0.044508773401636906 3.078847094675753e-07 6.5116118790044055 0.19246768847646334 QHVIDGEK ddPTM_PC-9_AZD4547_30min_R2 1 QHVIDGEK 8 0 Q9UQ80;Q9UQ80-2;F8VR77 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 0 93.598 0.005963 5619400.0 102010.0 87831.0 107000.0 144520.0 157240.0 135480.0 117000.0 121360.0 125400.0 132940.0 False True 134447.0580601881 116220.65312118255 105581.11008744208 111203.14681174204 135409.94015996714 127008.41418291832 127412.77334096715 102606.60057536513 132028.387990826 128285.81106378676 1.0480275016021672 0.9059509555845959 0.8230147138793442 0.866839020540231 1.0555332584103014 0.9900425708012768 0.9931945885863751 0.7998281316111154 1.0291737402289824 1.0 16.96900208570682 -4.752162134351641 24.586353279574368 0.934974475580327 1.0480277762404697 0.1262192291079991 0.08387052512091014 646.3199767034622 1712710.346911875 0.021483734319846147 0.25890359249333045 1.7694482501685237e-05 4.752162134351641 0.11305330066014274 QHYIDLK ddPTM_PC-9_Lapatinib_30min_R1 1 QHYIDLK 7 0 Q32Q12;P22392-2;J3KPD9;P22392;F6XY72;O60361 Q32Q12 NME1-NME2;NME2;NME2P1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Putative nucleoside diphosphate kinase 0 90.37 0.013406999999999999 15331000.0 132950.0 144170.0 155970.0 144340.0 137130.0 122920.0 126280.0 134700.0 129650.0 115600.0 False True 131054.10861995608 143836.1832227787 143146.74866161068 154955.245104125 129064.2830079532 117662.9981405152 132818.1605072144 140958.65374652648 115047.45172497477 135581.30597268266 0.9666089855069051 1.060885069596241 1.055800042894205 1.1428953570881362 0.9519327320387183 0.8678408671194118 0.9796200114341355 1.03966142482008 0.8485495172037574 1.0 17.0487987470134 -6.372435770768173 9.639043115576179 0.9471131067523403 1.0567163393444026 0.3917031750946153 0.06632357416362332 0.40642895666751155 32.670548720147536 0.020630335216948487 0.02338875879728069 4.241937146679587e-07 6.372435770768173 0.10960323259206228 QIASDS(ph)PHASPK ddPTM_PC-9_AZD4547_30min_R2 1 QIASDSPHASPK 12 0 Q9HCD6;Q9HCD6-2;Q9HCD6-3;Q9HCD6-4;J3KRP9 Q9HCD6 TANC2 Protein TANC2 1 QIASDS(0.997)PHAS(0.003)PK 121.92 0.0004245 2657300.0 9913.8 9547.1 17895.0 43146.0 22136.0 20220.0 12730.0 30786.0 13551.0 22847.0 True False 13066.182180149928 12633.01337128395 17657.70060761472 33199.356299054976 19062.79849517321 18955.64020356219 13862.94533872231 26028.731091901733 14267.278195085197 22047.13348408558 0.5926476650391568 0.5730002669237212 0.8009068671154319 1.5058355011557158 0.8646384124690599 0.8597779941435496 0.6287867467545876 1.1805947975363877 0.6471262218911059 1.0 14.42830347174371 -5.519357560218174 24.99918040729531 0.9577237982021899 0.6088562791054242 0.27532115896631826 0.240075462943003 183.28783014993905 1301277.5258950414 0.06568863083515203 0.11694503622312344 3.024422357052139e-06 5.519357560218174 -0.3488675190967657 QIASNS(ph)PGSSPK ddPTM_PC-9_AZD4547_30min_R2 1 QIASNSPGSSPK 12 0 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 QIAS(0.144)NS(0.856)PGS(0.001)SPK 155.26 1.5903e-09 0.0 23320.0 25671.0 31185.0 34477.0 34616.0 29366.0 29711.0 28629.0 22861.0 30205.0 True False 30735.27491386715 33968.6487262342 30771.466524082964 26528.860314340105 29810.165915653943 27529.739377735274 32355.221442166425 24205.04587897273 24069.3857883435 29147.53214368646 1.0544726312455446 1.1654039374167744 1.0557143010389733 0.9101580258514759 1.0227337864729318 0.9444964068321093 1.1100501161699472 0.8304320845981362 0.825777828108754 1.0 14.831086118385686 -5.568316857450898 0.49748432365297424 0.9176016202826109 1.1722308142634736 0.3251577575665837 0.08834883142278406 2.6832553513750796 0.8883119712354351 0.06720670475824436 0.36863091018233085 2.7019862992529423e-06 5.568316857450898 0.2546291939808627 QIASNS(ph)PGSSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QIASNSPGSSPK 12 0 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 QIAS(0.052)NS(0.948)PGSSPK 165.49 0.00082734 8177800.0 25581.0 23800.0 24199.0 29776.0 36067.0 26971.0 29758.0 25538.0 24280.0 22346.0 True False 29911.35805221957 26162.706711279603 24775.995935218565 28107.747255094477 28999.93025912584 25556.59328026807 26939.106810737096 24867.65455974767 24635.049066752854 26397.15290916134 1.1331281882993751 0.9911185043823278 0.9385859157038053 1.0648022289305095 1.0986006846617606 0.9681571860501081 1.0205307710055225 0.942058207766685 0.9332464433390869 1.0 14.688094714234152 -6.808733428997302 24.999497241181995 0.9721603075704287 1.0374008390523557 0.2916502754125254 0.055783183740818996 186.93730311557164 98813.16880590717 0.020700960337970895 0.018256575930885838 1.5533401613503607e-07 6.808733428997302 0.06524053148192699 QIASNS(ph)PGSSPK ddPTM_PC-9_Lapatinib_30min_R1 1 QIASNSPGSSPK 12 0 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 QIAS(0.013)NS(0.987)PGSSPK 160.63 5.9409e-12 0.0 33208.0 26972.0 28880.0 25806.0 26196.0 24674.0 24158.0 24276.0 31329.0 18623.0 True False 32734.44783039863 26909.547991154726 26505.597880023877 27703.859326292397 24655.20278331758 23618.75053790327 25408.78303399816 25403.951583895105 27800.39811100449 21841.9607364123 1.4986954800183154 1.2320115540860923 1.2135173302384397 1.268377855844592 1.1287998857270805 1.0813475412273277 1.1633013785085549 1.1630801781245161 1.2727977330651912 1.0 14.414814751270931 -1.5228789669590033 0.8004607537132323 1.1527555837598744 84.60314631578284 0.6484924921848262 0.07551054779986603 320.3747450520104 1.1120614143162129 0.026673430336891003 48482.340587088365 0.029999984686984175 1.5228789669590033 83.45039073202297 QICLVMLET(ph)LSQSPQGR ddPTM_PC-9_Lapatinib_30min_R1 1 QICLVMLETLSQSPQGR 17 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 QICLVMLET(0.658)LS(0.024)QS(0.318)PQGR 92.11200000000001 0.0080281 2559700.0 18246.0 13338.0 15619.0 15295.0 17392.0 15381.0 12329.0 13540.0 16816.0 13067.0 True False 17985.8086940934 13307.116680484276 14334.866111083546 16419.845322624282 16369.036753987593 14723.190484862223 12967.335293739698 14169.117830200172 14922.00499966967 15325.613539316959 1.173578378963548 0.8682925904627343 0.9353534900451647 1.0713988892190278 1.06808361779408 0.9606917496053744 0.8461217725784852 0.9245383745225034 0.9736644449103552 1.0 13.903657210882267 -6.992648056877125 23.940875349756162 0.9260232625331022 1.0126970845825591 0.18327694261354488 0.08565030257147133 187.2452923661403 609739.0452461351 0.0306452486632561 0.026962980709398208 1.0170725732408815e-07 6.992648056877125 0.08667382204945695 QICLVMLETLS(ph)QSPQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QICLVMLETLSQSPQGR 17 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 QICLVMLET(0.003)LS(0.499)QS(0.499)PQGR;QICLVMLET(0.009)LS(0.496)QS(0.496)PQGR 95.87299999999999 0.0014156 6301700.0 20227.4 20607.8 21691.8 24584.3 29554.0 26126.5 27245.6 21058.5 24642.8 17633.7 True False 23651.499310639378 22653.606191794446 22209.01477860962 23206.921374375986 23763.105855164147 24756.38034692536 24664.699526937897 20505.736688325094 25003.154330402685 20830.550221707614 1.135423647426847 1.087518378088113 1.0661751390256367 1.1140810553430291 1.140781477313091 1.1884650229318774 1.1840637556100029 0.9844068673210548 1.2003117567363526 1.0 14.346413327024267 -10.693955655609267 4.178352052347007 0.9999598911547201 1.1196815586581217 0.2593378477726045 0.061885778582260104 44026736.37307136 1.369774748437387 17435.241695687688 0.01487900076594596 2.023225753103663e-11 10.693955655609267 0.11972166750340163 QICLVMLETLS(ph)QSPQGR ddPTM_PC-9_Lapatinib_30min_R1 2 QICLVMLETLSQSPQGR 17 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 QICLVMLET(0.061)LS(0.584)QS(0.356)PQGR;QICLVMLET(0.002)LS(0.665)QS(0.333)PQGR 119.04 0.00010435 3774670.0 15536.6 12885.34 14418.86 12309.75 11679.8 12995.8 13781.5 12978.4 12722.3 10875.39 True False 15315.045234936511 12855.504786902935 13233.396989209172 13215.050079122213 10992.81712737031 12439.99992868944 14495.038636602614 13581.42384397859 11289.38060224176 12755.186670953723 1.2006915798270623 1.007864888106864 1.0374914401954176 1.0360530519883098 0.8618311445337995 0.9752895233605612 1.136403489069345 1.064776564572464 0.8850815666971056 1.0 13.638796392350168 QICLVMLETLSQS(ph)PQGR ddPTM_PC-9_AZD4547_30min_R2 7 QICLVMLETLSQSPQGR 17 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 QICLVMLET(0.001)LS(0.009)QS(0.99)PQGR;QICLVMLETLS(0.006)QS(0.994)PQGR;QICLVMLET(0.004)LS(0.077)QS(0.919)PQGR;QICLVMLET(0.015)LS(0.187)QS(0.798)PQGR;QICLVMLET(0.014)LS(0.373)QS(0.614)PQGR;QICLVMLETLS(0.066)QS(0.934)PQGR;QICLVMLETLS(0.033)QS(0.967)PQGR 204.81 3.2133e-17 518673000.0 590665.6 520682.2 922651.3 1072574.0 1008186.0 799295.0 686917.6 934527.0 772854.8 854809.0 True False 778484.9741922952 688982.538654622 910416.3409123505 825308.6354031103 868216.776457114 749314.957295066 748051.9356642835 790117.3254440869 813706.3269136555 824882.3970936108 0.9437526815158231 0.835249413834241 1.103692288888828 1.000516726155148 1.0525340091098894 0.9083900443689924 0.9068588907945767 0.9578545114163969 0.9864513169158015 1.0 19.6538289244331 -5.366429119565137 0.0030861443725454627 1.9263617535721174 5.861355647139427e-05 0.015048934206537745 0.07263324951722061 525546.3975955496 309.40153364006073 94802.23369379151 98336.91080721591 4.301014239958585e-06 5.366429119565137 -1.926303140015646 QICLVMLETLSQS(ph)PQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QICLVMLETLSQSPQGR 17 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 QICLVMLET(0.006)LS(0.167)QS(0.826)PQGR;QICLVMLETLS(0.003)QS(0.997)PQGR;QICLVMLETLS(0.033)QS(0.967)PQGR;QICLVMLET(0.008)LS(0.082)QS(0.91)PQGR 147.37 6.8594e-05 123876000.0 193156.0 191441.0 217533.0 231274.0 267877.0 224224.0 231694.0 215507.0 216856.0 180637.0 True False 225853.49579510244 210445.9972905072 222719.81171849676 218316.4675804247 215388.4248211342 212465.29871620738 209746.26700070294 209850.1695985407 220027.1087487538 213385.0581782945 1.058431633982497 0.9862264916162425 1.0437460505430636 1.0231103782253101 1.0093885047994586 0.9956896726043554 0.9829473009560437 0.983434226323381 1.031127064974294 1.0 17.703099632572993 -6.44542582913567 2.658104276304192 0.9967493607742055 1.0261631645291887 0.2931183909814109 0.02125433202122122 0.3671698899154323 5.097302172318292 0.00703796122434256 0.007894510352853011 3.5857018135793774e-07 6.44542582913567 0.029413803754983148 QICLVMLETLSQS(ph)PQGR ddPTM_PC-9_Lapatinib_30min_R1 5 QICLVMLETLSQSPQGR 17 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 QICLVMLET(0.027)LS(0.05)QS(0.923)PQGR;QICLVMLET(0.003)LS(0.001)QS(0.996)PQGR;QICLVMLET(0.201)LS(0.201)QS(0.598)PQGR;QICLVMLETLSQS(1)PQGR;QICLVMLETLS(0.38)QS(0.62)PQGR 297.7 3.671499999999999e-112 428896900.0 942637.8 767990.0 903026.0 712427.0 794128.0 840903.0 788678.0 730999.5 868309.0 709206.0 True False 929195.6121134002 766211.7663401639 828782.6880611662 764821.2581668021 747418.9523557189 804939.5389306347 829511.8878089087 764964.4054148749 770510.8967208717 831791.3121424059 1.117101848202904 0.9211586550076704 0.9963829580360842 0.9194869518375803 0.8985654712245394 0.9677181369656166 0.997259619930838 0.9196590469845037 0.9263271754261329 1.0 19.665862090901577 -4.755856444666753 24.99982056158309 0.9480858159089638 1.1171021169151085 0.6580480382836721 0.03620489723247465 109.93381839866854 492221.55756974505 0.008994421837206425 0.07684461847900553 1.7544603400104432e-05 4.755856444666753 0.16901630100614473 QICVVMLETLS(ph)QSPPK ddPTM_PC-9_AZD4547_30min_R2 2 QICVVMLETLSQSPPK 16 0 Q15366-2;Q15366;Q15366-5;H3BRU6;F8VZX2;Q15366-8 Q15366-2 PCBP2 Poly(rC)-binding protein 2 1 QICVVMLET(0.002)LS(0.972)QS(0.026)PPK;QICVVMLET(0.07)LS(0.465)QS(0.465)PPK 108.66 0.0006786 60735700.0 85176.0 82262.0 74951.0 65623.0 77516.0 91663.0 121071.0 122733.0 105112.0 86774.0 True False 112260.19622914019 108851.58277891307 73957.10076788659 50494.6312152432 66754.24142355635 85931.29811964004 131846.08445439526 103767.43497376639 110668.00572959891 83736.06867194994 1.3406432617339403 1.299936628328676 0.8832167779171233 0.6030212788358189 0.7971981785421198 1.0262160557870263 1.574543521632528 1.2392202860668404 1.3216288689544209 1.0 16.35356156607022 -7.031764674751049 21.585686983063653 1.303297528919073 0.9690818977203699 0.25697529808083674 0.24257898077415438 176.73245115771476 120097.22731555857 0.10135316769171786 0.0786589955552215 9.294698895722992e-08 7.031764674751049 -0.334215631198703 QICVVMLETLS(ph)QSPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QICVVMLETLSQSPPK 16 0 Q15366-2;Q15366;Q15366-5;H3BRU6;F8VZX2;Q15366-8 Q15366-2 PCBP2 Poly(rC)-binding protein 2 1 QICVVMLET(0.007)LS(0.654)QS(0.339)PPK;QICVVMLETLS(0.5)QS(0.5)PPK 114.58 0.00016799 74322800.0 207163.0 268294.0 175818.0 209285.0 211461.0 155831.0 237503.0 150179.0 155736.0 157573.0 True False 242231.60424424233 294928.4552267244 180010.16791347764 197559.43996112506 170026.73503548975 147658.94803520266 215004.996467185 146236.96037780322 158013.34437643408 186139.73755281797 1.3013427838078264 1.5844464975837689 0.9670700640286385 1.0613501585338097 0.9134359877736687 0.7932693468706744 1.1550730612058395 0.7856299912118864 0.8488963531045975 1.0 17.506026552674115 -5.2747238269163494 22.933169921656972 0.9386761068746678 1.4428945782581806 0.716422129015799 0.12640450078277612 111.41454920809474 192337.67186200942 0.03244381858527596 0.068337281033498 5.312221473965976e-06 5.2747238269163494 0.5042184713835127 QICVVMLETLSQS(ph)PPK ddPTM_PC-9_AZD4547_30min_R2 5 QICVVMLETLSQSPPK 16 0 Q15366-2;Q15366;Q15366-5;H3BRU6;F8VZX2;Q15366-8 Q15366-2 PCBP2 Poly(rC)-binding protein 2 1 QICVVMLET(0.001)LS(0.076)QS(0.923)PPK;QICVVMLET(0.001)LS(0.092)QS(0.907)PPK;QICVVMLETLS(0.033)QS(0.967)PPK;QICVVMLETLS(0.08)QS(0.92)PPK;QICVVMLET(0.001)LS(0.194)QS(0.805)PPK 210.2 2.2455999999999998e-17 299978200.0 711756.0 548609.0 543045.0 411298.0 509638.0 639688.0 808596.0 718554.0 627582.0 575411.0 True False 938079.6025555091 725936.1306162839 535843.8684806998 316479.60059075506 438883.5606922245 599688.2082362177 880559.4775419877 607517.990028271 660754.703285953 555266.0360314774 1.689423702663367 1.3073663496593395 0.9650218700758486 0.5699603074098597 0.7904023156700776 1.0800016016146576 1.58583349314034 1.0941025573439387 1.1899786055859098 1.0 19.08281962770932 -4.913056967456262 2.8590616372967372 1.0358757346743828 1.7193453140777324 0.4010001845051082 0.24870143553798774 0.3735183675887434 5.178947491253653 0.07377119081295694 0.5203600385545778 1.2216394042629067e-05 4.913056967456262 0.6834695794033496 QICVVMLETLSQS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QICVVMLETLSQSPPK 16 0 Q15366-2;Q15366;Q15366-5;H3BRU6;F8VZX2;Q15366-8 Q15366-2 PCBP2 Poly(rC)-binding protein 2 1 QICVVMLETLS(0.21)QS(0.79)PPK 195.28 8.4988e-12 74930000.0 466840.0 596440.0 366870.0 458410.0 463320.0 307800.0 492250.0 351940.0 313320.0 357580.0 True False 545866.7914897056 655650.621465362 375617.57216222363 432726.7738852719 372535.77197044966 291658.4261490682 445620.51641862036 342701.9479112533 317901.7122567958 422406.4233982776 1.2922786237438912 1.5521795719644245 0.8892326237379733 1.0244322763938263 0.8819368062004919 0.6904687286776177 1.0549567708596483 0.8113085619158005 0.7525967756343831 1.0 18.688272247898283 -5.270456121984141 24.59094894309819 0.8849250019542703 1.4222290989049724 0.7450527981854607 0.12496418841936044 210.52531866510688 574157.5084036827 0.03211179295996609 0.06845181184042529 5.364680696085273e-06 5.270456121984141 0.5373040969507021 QICVVMLETLSQS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 7 QICVVMLETLSQSPPK 16 0 Q15366-2;Q15366;Q15366-5;H3BRU6;F8VZX2;Q15366-8 Q15366-2 PCBP2 Poly(rC)-binding protein 2 1 QICVVMLETLS(0.185)QS(0.814)PPK;QICVVMLET(0.005)LS(0.053)QS(0.942)PPK;QICVVMLETLS(0.004)QS(0.996)PPK;QICVVMLETLS(0.093)QS(0.907)PPK;QICVVMLETLS(0.002)QS(0.998)PPK;QICVVMLETLS(0.393)QS(0.607)PPK;QICVVMLETLSQS(1)PPK 316.84 3.451299999999999e-147 328328400.0 405584.0 722215.0 549164.0 628392.0 695908.0 671851.0 674107.0 596802.0 621915.0 599025.0 True False 399800.29778500384 720542.755540257 504013.85575434234 674606.04393426 654976.0596477698 643117.4988911749 709008.9620291167 624531.5996528154 551868.3836447168 702565.6730993615 0.5690575459249081 1.0255877608730721 0.7173903807894431 0.9602035365010678 0.932263110377069 0.9153841747691265 1.0091710841796906 0.8889298517784116 0.7855043375662732 1.0 19.422273563580163 -4.749204719959275 24.9951045637847 0.9102076473922035 0.5690567633494578 0.5515932416952956 0.0934687266318868 433.74660058792324 886079.5538910839 0.02235999367434735 0.3756725405947912 1.7815387786020656e-05 4.749204719959275 -0.34115088404274574 QIDNPDYK ddPTM_PC-9_AZD4547_30min_R2 2 QIDNPDYK 8 0 P27797;K7EJB9;K7EL50 P27797 CALR Calreticulin 0 ; 116.05 0.01662 14503600.0 114152.0 106908.0 145104.0 161327.0 140293.0 134691.0 132331.0 154938.0 135993.0 144912.0 False True 150449.96149089912 141463.92030011475 143179.8261507307 124135.55262730352 120815.73858345379 126268.7504776454 144108.2026408847 130995.89222104431 143181.31234478793 139838.67498777996 1.075882344451894 1.0116222877002863 1.0238928977498014 0.8877054408456839 0.8639651269150789 0.9029601466738698 1.0305318085535196 0.9367643982073744 1.0239035256684181 1.0 17.093403894496547 -5.629299800792545 7.334716520017729 0.9447962782958809 1.0372807531094228 0.347013309122838 0.055165521804246206 0.2594345716813536 15.952286504063666 0.01598158970798961 0.027797790816847964 2.34801138946925e-06 5.629299800792545 0.09248447481354194 QIDNPDYK ddPTM_PC-9_Lapatinib_30min_R1 2 QIDNPDYK 8 0 P27797;K7EJB9;K7EL50 P27797 CALR Calreticulin 0 ; 152.34 0.0010707000000000002 28862000.0 226300.0 194767.0 201796.0 187828.0 183050.0 171271.0 188865.0 179253.0 177443.0 169191.0 False True 223072.9205016627 194316.0289779487 185205.11183508686 201641.4976958397 172283.3588901465 163946.13858220135 198643.50557645765 187581.74877524894 157457.5007823732 198435.43891716318 1.1241586770938856 0.979240553191035 0.9333267930654296 1.0161566844923042 0.8682086215560828 0.8261938466074128 1.001048535787911 0.9453036705482577 0.7934948597972149 1.0 17.59831017649374 -1.5228787452866313 0.7594374049847693 0.912419273745898 40.25057989377619 0.43315758451462205 0.07041188756909171 379.3840371924202 1.5742720799319496 0.02603896342282759 25562.145655797587 0.029999999999565246 1.5228787452866313 39.338160620030294 QIDS(ph)SPVGGETDETTVSQNYR ddPTM_PC-9_AZD4547_30min_R2 1 QIDSSPVGGETDETTVSQNYR 21 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0 O15027 SEC16A Protein transport protein Sec16A 1 QIDS(0.776)S(0.217)PVGGET(0.006)DETTVSQNYR 49.515 0.027288999999999997 6592100.0 6830.6 8404.8 14081.0 19491.0 15286.0 11974.0 13431.0 15305.0 12801.0 13612.0 True False 9002.588714693864 11121.48723517795 13894.276739638048 14997.65108294814 13163.802755566396 11225.263887114425 14626.332980705358 12939.963923912033 13477.634726240542 13135.448023170351 0.6853659425101979 0.8466774194195841 1.057769534402569 1.1417692838868492 1.0021586421982736 0.8545779228324419 1.1135008836322258 0.9851178201981773 1.026050630512685 1.0 13.681177788226774 -5.0002945191555455 2.9185208235515274 1.0222876486886618 0.6870014376154823 0.6788906586559504 0.07445459239873062 0.16886983958822127 2.6840312229995806 0.0203759360886437 0.10527441734773121 9.993220744782536e-06 5.0002945191555455 -0.3352862110731796 QIDS(ph)SPVGGETDETTVSQNYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QIDSSPVGGETDETTVSQNYR 21 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0 O15027 SEC16A Protein transport protein Sec16A 1 QIDS(0.5)S(0.5)PVGGETDETTVSQNYR 143.52 0.00019141 59616000.0 22079.0 20554.0 21461.0 22270.0 23122.0 22070.0 22427.0 21538.0 17593.0 18968.0 True False 25816.53861987239 22594.46528334625 21972.711631295726 21022.284100314166 18591.410082665814 20912.610347985465 20302.55220258085 20972.650321397352 17850.264342313953 22406.74824939463 1.152176939399044 1.008377700854326 0.9806292009323294 0.9382121790421835 0.8297237009019416 0.9333175039600164 0.9060909676230852 0.9359970526720215 0.796646802277355 1.0 14.451645674320806 -4.310674401091968 0.8212137163043185 0.8986959323670951 1.5172276226026993 0.6533825769562446 0.05529512259518906 2.8063444531576236 0.8520966761946128 0.01920889730135801 1.8916156600512668 4.890188487597228e-05 4.310674401091968 0.6185316902356042 QIDSS(ph)PVGGETDETTVSQNYR ddPTM_PC-9_AZD4547_30min_R2 2 QIDSSPVGGETDETTVSQNYR 21 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0 O15027 SEC16A Protein transport protein Sec16A 1 QIDS(0.242)S(0.758)PVGGETDETTVSQNYR;QIDS(0.224)S(0.775)PVGGET(0.001)DETTVSQNYR 159.47 7.2230999999999995e-06 166811000.0 67164.0 52030.0 87644.0 118131.0 111779.0 86594.0 72382.0 105667.0 71874.0 82771.0 True False 88520.75490201451 68847.67999789506 86481.78329442779 90897.72305575629 96260.41529598691 81179.2634909628 78823.85777748609 89338.59313610008 75673.11290632078 79873.2124835317 1.1082658647323815 0.8619620753589962 1.082738262371238 1.1380251304465516 1.2051651899669609 1.0163515522516435 0.9868622448826387 1.1185050702013515 0.9474154169262079 1.0 16.285424119286695 -10.409748348148014 12.662745975573277 1.0000076257765902 1.0531024102027438 0.02530384475237546 0.09590438418521978 0.0 0.0 0.09517772463910248 0.023083988934880714 3.89270642452828e-11 10.409748348148014 0.05309478442615356 QIDSS(ph)PVGGETDETTVSQNYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QIDSSPVGGETDETTVSQNYR 21 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0 O15027 SEC16A Protein transport protein Sec16A 1 QIDS(0.003)S(0.997)PVGGETDETTVSQNYR;QIDS(0.223)S(0.777)PVGGETDETTVSQNYR 275.31 6.464599999999998e-209 60101000.0 58157.0 64870.0 78820.0 80786.0 86732.0 73343.0 76682.0 72595.0 68665.0 50697.0 True False 68001.83144689155 71309.86488910536 80699.36772651464 76259.82233174579 69737.48721087145 69496.76396702764 69418.12583039666 70689.45817076034 69669.09572358248 59887.9647827688 1.1354840942341942 1.190721126486217 1.347505596812897 1.2733747524792753 1.1644658065076974 1.1604462469064154 1.159133159428552 1.1803616707826308 1.163323816000305 1.0 15.869978484520658 -6.389612531629126 5.007827503840301 1.1472876040069602 1.2409902051090898 0.31798705626833257 0.07034082142747006 0.3154073817690469 11.530857198391086 0.02271007644229995 0.025770369219249578 4.077438960722723e-07 6.389612531629126 0.09370260110212958 QIDSS(ph)PVGGETDETTVSQNYR ddPTM_PC-9_Lapatinib_30min_R1 3 QIDSSPVGGETDETTVSQNYR 21 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0 O15027 SEC16A Protein transport protein Sec16A 1 QIDS(0.038)S(0.962)PVGGETDETTVSQNYR;QIDS(0.013)S(0.987)PVGGETDETTVSQNYR;QIDS(0.071)S(0.928)PVGGET(0.001)DETTVSQNYR 222.13 4.1661999999999992e-53 163749000.0 121194.0 119416.0 131735.0 99984.0 113830.0 117936.0 93502.5 89128.0 119261.0 88341.3 True False 119465.75133574224 119139.499588897 120904.25681180556 107337.15689684654 107134.74319839067 112892.15220224367 98343.6019387538 93269.21225776098 105828.57030599454 103610.97599761696 1.1530221599156631 1.149873345384153 1.1669058769853335 1.035963186943778 1.0340095937408673 1.0895771525676987 0.9491620071315194 0.900186600499798 1.0214030828975935 1.0 16.66081731702269 -6.217935196480316 0.7300349242088184 0.9645597203307767 1.174374809792349 0.693931381744818 0.047010122149789946 0.4416029836357976 0.5003998024778245 0.02885776268340923 0.054593569676422385 6.054312078062647e-07 6.217935196480316 0.20981508946157224 QIEHCEGR ddPTM_PC-9_AZD4547_30min_R2 1 QIEHCEGR 8 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 0 90.15 0.0081334 1059400.0 6308.6 5335.4 4495.6 8658.9 9354.5 7297.9 6724.6 6540.4 8169.2 8796.0 False True 8314.603572968366 7059.963710566392 4435.985406627141 6662.724383671421 8055.789145423643 6841.561159326236 7323.076372723642 5529.731463440333 8601.00723424766 8488.054717294035 0.9795652655287118 0.831752851001541 0.5226150813553331 0.7849530434925702 0.9490736586570689 0.8060222733233396 0.8627508441720102 0.6514721744398926 1.013307232424349 1.0 13.051218241116734 -8.290404928439932 24.068727462662665 1.006653862909764 0.7973927775835191 0.30385979621215176 0.1259998297815377 666.2220883419187 553583.9440836472 0.12520645143552345 0.03235716187100555 5.123834240265457e-09 8.290404928439932 -0.209261085326245 QIEHCEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QIEHCEGR 8 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 0 93.178 0.006227300000000001 843980.0 5095.2 6734.2 5838.1 6554.4 7829.7 6952.8 4753.9 6524.8 7721.3 4908.1 False True 5957.716725212822 7402.726871222653 5977.302445117543 6187.178217651508 6295.526490971735 6588.182928295128 4303.576176744504 6353.530913597056 7834.209405235532 5797.8996775017795 1.027564645233721 1.2767945778620937 1.0309427167758558 1.067141303196447 1.0858288071801159 1.1363050923181666 0.7422646848209772 1.0958331925354543 1.3512150676969226 1.0 12.501314654966734 QILIACS(ph)PVSSVR ddPTM_PC-9_AZD4547_30min_R2 4 QILIACSPVSSVR 13 0 Q5QJE6;J3KP30;E9PRB3 Q5QJE6 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 QILIACS(0.999)PVSSVR;QILIACS(0.868)PVS(0.129)S(0.003)VR;QILIACS(0.998)PVS(0.002)SVR;QILIACS(0.976)PVS(0.022)S(0.002)VR 182.02 7.482e-05 275343000.0 332755.0 252017.0 425266.0 523346.0 496382.0 462082.0 391622.0 476386.0 368390.0 428551.0 True False 438564.16826603276 333476.5667889587 419626.69497613166 402696.66531509784 427467.9274770096 433187.93949270074 426475.5993276594 402771.4899612387 387862.34331690904 413547.5599307716 1.0604926996533337 0.8063802065348495 1.0146999659395348 0.9737614347972693 1.0336608624859698 1.047492432467059 1.0312613122395209 0.9739423683908646 0.9378905376248325 1.0 18.65769373014684 QILIACS(ph)PVSSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QILIACSPVSSVR 13 0 Q5QJE6;J3KP30;E9PRB3 Q5QJE6 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 QILIACS(0.928)PVS(0.07)S(0.003)VR;QILIACS(1)PVSSVR;QILIACS(0.999)PVS(0.001)SVR;QILIACS(0.992)PVS(0.008)SVR 168.45 5.3568999999999995e-05 203085000.0 285982.0 272543.0 333935.0 356762.0 406657.0 348718.0 372489.0 347857.0 297921.0 266905.0 True False 334393.10419803247 299599.2678660622 341897.2768555406 336773.7817780092 326975.48006170004 330430.61419704556 337204.1453331765 338726.1223349568 302277.53101384145 315292.7636811821 1.0605796983535094 0.950225639079402 1.0843803481682834 1.068130387282051 1.0370535506242422 1.0480120455005766 1.0694953521805237 1.0743225387737412 0.9587201668843202 1.0 18.266332533385828 -8.26443616336169 24.99005163527645 0.9793600794912505 1.0477965336892698 0.36347510890453516 0.036847347050316274 304.08550803159926 2535685.106224608 0.031223244075850996 0.009378041895955019 5.439560815635556e-09 8.26443616336169 0.06843645419801936 QILIACS(ph)PVSSVR ddPTM_PC-9_Lapatinib_30min_R1 4 QILIACSPVSSVR 13 0 Q5QJE6;J3KP30;E9PRB3 Q5QJE6 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 QILIACS(1)PVSSVR;QILIACS(1)PVSSVR;QILIACS(0.997)PVS(0.002)SVR;QILIACS(0.963)PVS(0.037)S(0.001)VR 156.96 0.00010237 243975000.0 323633.0 362048.0 424172.0 386113.0 416119.0 398104.0 312019.0 328142.0 415652.0 307403.0 True False 319017.93407297705 361209.70010016294 389298.2155112693 414509.03805520886 391643.69854143093 381078.0199457504 328173.81709930743 343388.6752612658 368836.89475039835 360537.19896124926 0.8848405517991093 1.0018652753193047 1.079772674311788 1.1496983924251336 1.0862781972839508 1.0569728201241972 0.9102356651264153 0.952436187585108 1.0230203591004243 1.0 18.459788593787103 -7.2360294135184375 24.11942774303016 0.967459397209266 1.0498135700110378 0.19611218021182908 0.0702970500596035 785.8591983927214 745947.2592687336 0.029262970474797464 0.02265661124138739 5.8072508534658024e-08 7.2360294135184375 0.08235417280177182 QIPS(ph)AEDLETDGGGPGQVVDDGLEHR ddPTM_PC-9_AZD4547_30min_R2 3 QIPSAEDLETDGGGPGQVVDDGLEHR 26 0 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;Q8WUI4-10 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 QIPS(0.902)AEDLET(0.098)DGGGPGQVVDDGLEHR;QIPS(0.945)AEDLET(0.055)DGGGPGQVVDDGLEHR;QIPS(1)AEDLETDGGGPGQVVDDGLEHR 79.616 2.2699e-05 7143200.0 4398.2 5336.3 19999.1 22548.7 16022.5 18268.4 11251.7 21362.4 14945.2 13048.5 True False 5796.736111756881 7061.154617965936 19733.898866820186 17350.445588942228 13798.052443481783 17126.074060076928 12253.079502568877 18061.33193911652 15735.17276076949 12591.675986654285 0.4603625536346987 0.5607795678232144 1.5672178102212786 1.3779298011902217 1.0958074570935685 1.360110765098195 0.9731094983349093 1.4343866502171303 1.2496487979397617 1.0 13.62018270205916 -5.197615940313487 7.557842585048441 1.2644359927550766 0.5015756750831605 0.7296228809399481 0.1818279186838053 0.14068469916005125 14.762612122359986 0.045045048461658556 0.12044107543807865 6.344305092564952e-06 5.197615940313487 -0.7628603176719161 QIPS(ph)AEDLETDGGGPGQVVDDGLEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QIPSAEDLETDGGGPGQVVDDGLEHR 26 0 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;Q8WUI4-10 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 QIPS(0.994)AEDLET(0.006)DGGGPGQVVDDGLEHR 89.79299999999999 3.5303000000000003e-07 2005400.0 4664.7 6315.4 5892.0 8086.7 7844.6 5459.5 6277.6 6662.7 8026.5 6572.5 True False 5454.341577975396 6942.351174975432 6032.48762553443 7633.628416435136 6307.506942932287 5173.194209099534 5682.940282111803 6487.811184714178 8143.872377853862 7764.0422221186245 0.7025131267881016 0.8941671073345898 0.7769776944732155 0.9832028469252836 0.8123998765698516 0.6663016584791178 0.7319563855438517 0.8356228623063576 1.0489217014628227 1.0 12.922592248344206 -8.199518197562218 4.844558718032752 1.0249693546002705 0.800708989722721 0.5131926014232622 0.08767883390974567 0.1718271653680024 8.056979942817252 0.06887518694749042 0.02375256367391703 6.316577113681509e-09 8.199518197562218 -0.22426036487754952 QIPS(ph)AEDLETDGGGPGQVVDDGLEHR ddPTM_PC-9_Lapatinib_30min_R1 2 QIPSAEDLETDGGGPGQVVDDGLEHR 26 0 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;Q8WUI4-10 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 QIPS(1)AEDLETDGGGPGQVVDDGLEHR;QIPS(0.997)AEDLET(0.003)DGGGPGQVVDDGLEHR 137.47 3.6206999999999997e-10 4939900.0 11187.0 9810.9 18435.1 8348.5 13595.7 15005.4 11670.9 11573.599999999999 18121.6 15487.699999999999 True False 11027.471328555448 9788.183463829893 16919.43723954391 8962.476539779587 12796.027656174636 14363.654021295852 12275.162095847723 12111.35170750404 16080.554579092177 18164.72830893695 0.6070815451244592 0.5388565849902726 0.9314445529702549 0.4933999775471509 0.7044436579807836 0.7907442256776839 0.6757690997122379 0.6667510519023464 0.8852625982399435 1.0 14.148852166977461 -14.52287861338382 0.12019906671317483 2.056894641548962 0.5414164023564965 0.4279017103139171 0.12113553670722356 151.5750274253821 1.17613383051369 38.34593328119929 1.139882746593848 3.0000009111089997e-15 14.52287861338382 -1.5154782391924657 QIPSAEDLET(ph)DGGGPGQVVDDGLEHR ddPTM_PC-9_Lapatinib_30min_R1 1 QIPSAEDLETDGGGPGQVVDDGLEHR 26 0 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;Q8WUI4-10 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 QIPS(0.151)AEDLET(0.849)DGGGPGQVVDDGLEHR 69.094 0.019979 0.0 2716.9 2875.5 4010.3 3544.9 2894.5 2568.8 2039.6 2876.4 3039.6 2894.4 True False 2678.1565077815617 2868.8419564201945 3680.588614205669 3805.6037714397416 2724.2512008059525 2458.938412165272 2145.200508160555 3010.0480448144613 2697.248239593005 3394.6931834544266 0.7889244662329925 0.8450960959897036 1.0842183417767128 1.1210449857407065 0.80250292252738 0.7243477626048861 0.6319276565599979 0.886692222874601 0.7945484595601349 1.0 11.729065472471872 -6.478498996631446 22.449116486932407 0.7865565921289812 0.9606699082876342 0.24444749356241557 0.12933187268169039 190.23133774775602 96226.29154989083 0.04216908363139364 0.04780964769819344 3.322775528848007e-07 6.478498996631446 0.174113316158653 QIS(ph)LPDLSQEEPQLK ddPTM_PC-9_Lapatinib_30min_R1 3 QISLPDLSQEEPQLK 15 0 H0YBZ4;Q15390-2;Q15390 H0YBZ4 MTFR1 Mitochondrial fission regulator 1 1 QIS(1)LPDLSQEEPQLK;QIS(1)LPDLSQEEPQLK;QIS(1)LPDLSQEEPQLK 125.98 2.4903000000000002e-05 2720400.0 64185.0 50367.0 59869.0 55828.0 57444.0 52637.0 49793.0 53309.0 61919.0 51432.9 True False 63269.710129912535 50250.378306039245 54946.801921023136 59933.77735674851 54065.256859249304 50385.838212840026 52371.03790097982 55785.93075407251 54945.030184023926 60323.00823496859 1.0488487225880054 0.8330217569771271 0.9108763559502172 0.9935475552428693 0.8962626109204591 0.8352673330974881 0.8681768272726973 0.924786949231322 0.9108469851172457 1.0 15.880420755394999 -3.9401083751493573 15.39077068725931 0.9146344919378113 0.9200112844621563 0.0 0.06864048910511324 0.0 0.0 0.015254867080178562 0.0 0.0001147867143539626 3.9401083751493573 0.0053767925243449755 QIS(ph)QDFSELSTQLTGVAR ddPTM_PC-9_AZD4547_30min_R2 1 QISQDFSELSTQLTGVAR 18 0 A0A0A0MSQ9;Q86VX9-5;Q86VX9 A0A0A0MSQ9 MON1A Vacuolar fusion protein MON1 homolog A 1 QIS(0.937)QDFS(0.04)ELS(0.005)T(0.009)QLT(0.009)GVAR 86.22200000000001 0.0017652000000000002 1211100.0 3461.0 1415.6 3558.5 5902.8 3449.1 1758.3 3540.1 5802.3 3803.5 4894.2 True False 4561.526006727882 1873.1650164332164 3511.311964917403 4542.000657350898 2970.2520007996873 1648.3532230427 3855.1620419175847 4905.68785858966 4004.545245000851 4722.855547678542 0.9658406785212901 0.3966170460906741 0.7434722340054085 0.96170645311891 0.628910194439395 0.3490162268149248 0.8162777800418941 1.0387122386161032 0.8479076280385567 1.0 12.205443694841476 -7.521242160171132 24.41919278803783 0.9514850742889507 0.6680286919624031 0.3064598898981016 0.1944953443300088 60.81770440812208 907514.8142165764 0.09118905053417298 0.0536784522070352 3.011326457201457e-08 7.521242160171132 -0.2834563823265476 QIS(ph)QDVK ddPTM_PC-9_AZD4547_30min_R2 2 QISQDVK 7 0 E9PJF6;A0A5F9UK94;H0Y360;Q01433-2;Q01433;E9PIJ1;A0A590UK85;A0A590UJY6;Q01433-3;Q01433-5;Q01433-4 E9PJF6 AMPD2 AMP deaminase 2 1 QIS(1)QDVK;QIS(1)QDVK 110.84 0.009406 72578000.0 374740.0 392760.0 419120.0 417980.0 447890.0 498630.0 570660.0 655070.0 575030.0 482580.0 True False 493899.52492378117 519711.98915958573 413562.19495185633 321621.16872662597 385708.2046441601 467450.58727508417 621447.6344850966 553843.9835110786 605424.9118529886 465685.02108591975 1.060587097631074 1.1160161173912826 0.8880727878845674 0.6906410001692673 0.8282598477072257 1.0037913312844964 1.3344806174696315 1.1893102814850758 1.300073836262143 1.0 18.828994952574 -7.082488644251424 5.1089482937406245 1.219618866438711 0.9134954959226587 0.4955006030368104 0.1376771625027357 0.19680880378195814 8.815144037163668 0.057628385733172464 0.04477459967515142 8.27011132622815e-08 7.082488644251424 -0.30612337051605243 QIS(ph)QDVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QISQDVK 7 0 E9PJF6;A0A5F9UK94;H0Y360;Q01433-2;Q01433;E9PIJ1;A0A590UK85;A0A590UJY6;Q01433-3;Q01433-5;Q01433-4 E9PJF6 AMPD2 AMP deaminase 2 1 QIS(1)QDVK;QIS(1)QDVK;QIS(1)QDVK;QIS(1)QDVK 85.807 0.019036 62469000.0 412828.0 514362.0 414998.0 486205.0 518618.0 450750.0 588563.0 422049.0 413766.0 441488.0 True False 482711.6266753342 565424.4600599656 424893.12620867847 458964.5101478786 416998.5258304643 427111.8764999748 532810.0518128858 410970.66094787983 419816.54498163273 521526.2795829155 0.9255748858166403 1.0841725186162376 0.8147108647113273 0.880041002947982 0.7995733717655685 0.8189652050545804 1.0216360568426088 0.788015248774326 0.804976779535206 1.0 18.9923804260672 -5.269675883501037 24.9729794469119 0.8604280871455324 1.0048737045705387 0.2919138890866324 0.08617459483929778 620.6283958730263 1881742.0770033458 0.021800399270951943 0.04666364354823773 5.374327359179704e-06 5.269675883501037 0.14444561742500628 QIS(ph)QDVK ddPTM_PC-9_Lapatinib_30min_R1 2 QISQDVK 7 0 E9PJF6;A0A5F9UK94;H0Y360;Q01433-2;Q01433;E9PIJ1;A0A590UK85;A0A590UJY6;Q01433-3;Q01433-5;Q01433-4 E9PJF6 AMPD2 AMP deaminase 2 1 QIS(1)QDVK;QIS(1)QDVK 104.43 0.01035 82427000.0 418900.0 472420.0 415260.0 433270.0 610260.0 526500.0 669710.0 583740.0 570370.0 549260.0 True False 412926.40918314864 471326.14051539835 381118.9257499547 465134.1211463504 574365.7066173222 503982.82233144506 704384.3068838032 610862.6914476391 506128.9243376305 644198.859157056 0.6409921460020422 0.7316469655536736 0.5916168902389157 0.7220349967011515 0.8915969012563736 0.7823404452949735 1.0934268151382647 0.9482517436416487 0.7856718731230103 1.0 19.297146580221316 -6.360451905361486 1.478132129103948 0.9377877249246644 0.6568407167217288 0.6384653408257162 0.09176608826033968 0.2623684467871074 1.1531968742360987 0.035711211669581494 0.04522766192900547 4.360618516871871e-07 6.360451905361486 -0.2809470082029356 QIS(ph)QDVKLEPDILLR ddPTM_PC-9_Lapatinib_30min_R1 1 QISQDVKLEPDILLR 15 1 E9PJF6;A0A5F9UK94;H0Y360;Q01433-2;Q01433;E9PIJ1;A0A590UK85;A0A590UJY6;Q01433-3;Q01433-5;Q01433-4 E9PJF6 AMPD2 AMP deaminase 2 1 QIS(1)QDVKLEPDILLR 62.916000000000004 0.019454 4759900.0 13304.0 8075.2 10592.0 9319.8 11824.0 10726.0 10418.0 6138.0 13157.0 7675.6 True False 13114.282520345201 8056.502370538809 9721.16664630238 10005.209181941405 11128.535566878414 10267.27398352722 10957.393064334505 6423.19388787066 11675.12011064783 9002.317232905883 1.4567674278805665 0.8949365104675642 1.0798515976274319 1.1114037556207954 1.2361856707515964 1.1405145717368836 1.2171747318881738 0.7135045035285097 1.2969016541621234 1.0 13.13608068945177 QISGQYS(ph)GSPQLLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QISGQYSGSPQLLK 14 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GUE9;Q96N67-7 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 QISGQYS(0.5)GS(0.5)PQLLK 141.34 0.00013269 3545500.0 13675.0 16015.0 17512.0 19471.0 22010.0 18252.0 16145.0 18384.0 12134.0 17385.0 True False 15989.907406438466 17604.86336055221 17929.552494629836 18380.102995833724 17697.298500107023 17294.83298919035 14615.62872032228 17901.439479458102 12311.436794727302 20536.762880415714 0.7785992125217931 0.8572365305605479 0.8730466724007332 0.8949854026586329 0.8617374901369454 0.8421401702837531 0.7116812325987387 0.8716777606917441 0.5994828331230209 1.0 14.325921173453787 -7.027027089134884 22.735624341370723 0.7838588668212494 0.8562981338485851 0.06368520933691468 0.10073633313293183 539.8240857305778 454106.27132344025 0.035564993237923906 0.027662331689933477 9.396646971153034e-08 7.027027089134884 0.07243926702733572 QISNEVDS(ph)EDLK ddPTM_PC-9_AZD4547_30min_R2 1 QISNEVDSEDLK 12 0 Q8NEZ4;Q8NEZ4-3;H0YMU7 Q8NEZ4 KMT2C Histone-lysine N-methyltransferase 2C 1 QIS(0.4)NEVDS(0.6)EDLK 70.438 0.029773 13250000.0 23191.0 27998.0 26865.0 30117.0 29979.0 36214.0 29048.0 39888.0 37646.0 33643.0 True False 30565.25559723383 37047.805969269 26508.75254672083 23173.990953011627 25816.933325207683 33949.53285518307 31633.215726567596 33724.22613505412 39635.89070416775 32465.168810132247 0.9414784126332507 1.1411555007133223 0.8165290222808747 0.7138108872478469 0.795219438906793 1.045721741159946 0.9743739794353079 1.0387817889469568 1.2208743141294727 1.0 14.986605090559618 -7.377232455136829 1.4871083120957944 1.0967987749892512 0.8919199191432737 0.30732228555243024 0.12460468450824322 0.5656167578607256 2.4192254828104813 0.086457751309727 0.04650303653786722 4.195343690641597e-08 7.377232455136829 -0.20487885584597743 QIT(ph)MEELVR ddPTM_PC-9_Lapatinib_30min_R1 2 QITMEELVR 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 QIT(1)MEELVR;QIT(1)MEELVR 114.76 0.004937899999999999 3535800.0 12516.5 9013.3 13188.599999999999 11892.2 10890.9 10152.2 8035.099999999999 9514.2 11427.4 12814.1 True False 12338.012414755021 8992.430257625507 12104.284217468232 12766.792059216246 10250.318674333232 9718.014071934085 8451.118161953753 9956.264465294726 10140.325876143277 15029.000111285028 0.8209469907110195 0.5983385581901247 0.8053951778454859 0.849477141837924 0.6820359703528405 0.6466174728841069 0.5623207198999186 0.6624701837495317 0.674717266688226 1.0 13.875461408599081 -10.608857658981247 4.340278322211784 1.0000312394160746 0.6974592256100314 0.49427977284091074 0.09091774171596637 62711205.681068175 76108899.97963405 25017.003027975512 0.024122774023771495 2.4611741274708956e-11 10.608857658981247 -0.30257201380604326 QITQEEDDS(ph)DEEVAPENFFSLPEK ddPTM_PC-9_AZD4547_30min_R2 2 QITQEEDDSDEEVAPENFFSLPEK 24 0 Q92733 Q92733 PRCC Proline-rich protein PRCC 1 QIT(0.015)QEEDDS(0.985)DEEVAPENFFSLPEK;QIT(0.002)QEEDDS(0.998)DEEVAPENFFSLPEK 74.36399999999999 0.00045803 4232700.0 25576.0 24013.0 29147.0 30838.0 31505.0 36131.0 30082.0 34912.0 33912.0 32760.0 True False 33708.635986152076 31774.73265019132 28760.491735688505 23728.775542350566 27131.074565885083 33871.72285830395 32759.239723444174 29517.152597949476 35704.51908727987 31613.08237136793 1.0662875448261284 1.0051133982104128 0.9097655014411683 0.7505998707624219 0.8582230055003363 1.0714463860373726 1.0362557924156843 0.9337005563457252 1.1294222647399157 1.0 14.948234088790135 -6.765483608274762 24.993588607955566 1.0301519635365246 0.9130803724009887 0.2873472263337048 0.09119861074523476 153.68419035109844 949771.2657562615 0.034568414350948214 0.03159938223664431 1.7159964763409296e-07 6.765483608274762 -0.11707159113553589 QITQEEDDS(ph)DEEVAPENFFSLPEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QITQEEDDSDEEVAPENFFSLPEK 24 0 Q92733 Q92733 PRCC Proline-rich protein PRCC 1 QIT(0.002)QEEDDS(0.998)DEEVAPENFFSLPEK 123.3 1.7022e-06 0.0 23331.0 24215.0 25654.0 30159.0 31725.0 27537.0 30336.0 21376.0 23089.0 22897.0 True False 27280.477491745216 26618.905168640147 26265.68865333679 28469.28900679723 25508.713989818058 26092.911243882012 27462.35446637945 20814.902649744145 23426.632944903467 27048.044847447723 1.0085933251593018 0.984134170095179 0.9710753143702823 1.052545171651607 0.9430890156271344 0.9646875177502584 1.0153175440690243 0.769552947990925 0.8661118789557917 1.0 14.72323669297918 -7.740442451862871 24.99999658192797 0.8633742625748554 0.9897637644291483 0.4220596089345232 0.05967739175024953 183.73477467976994 218764.26230709764 0.02665986276725564 0.015371954360884994 1.8178479222243922e-08 7.740442451862871 0.12638950185429287 QITQEEDDS(ph)DEEVAPENFFSLPEK ddPTM_PC-9_Lapatinib_30min_R1 1 QITQEEDDSDEEVAPENFFSLPEK 24 0 Q92733 Q92733 PRCC Proline-rich protein PRCC 1 QIT(0.002)QEEDDS(0.998)DEEVAPENFFSLPEK 90.79899999999999 6.9075e-06 3023600.0 39085.0 44867.0 43255.0 44104.0 47050.0 48989.0 38708.0 41640.0 45496.0 39728.0 True False 38527.640732688844 44763.11321812024 39698.74086912854 47347.55528663102 44282.61150385906 46893.854668936685 40712.110840301415 43574.74641429363 40371.76138588082 46594.93186576749 0.8268633344862653 0.960686311272556 0.8519969721920451 1.0161524739006318 0.9503739941380351 1.0064153501507491 0.8737454742414146 0.9351821039212048 0.866441043463383 1.0 15.507885420914834 -4.102062537500442 2.0669479298552336 0.9387754676967458 8.805219973156361e-13 0.2522995439083203 0.05700205908689254 18.129129374620824 10.107515812872583 0.014714859961234396 63.54177757498487 7.905647801220792e-05 4.102062537500442 -0.9387754676958653 QITT(ph)SPITVR ddPTM_PC-9_AZD4547_30min_R2 1 QITTSPITVR 10 0 O95835;O95835-2 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 QIT(0.088)T(0.424)S(0.424)PIT(0.064)VR 91.31299999999999 0.01993 4097100.0 33462.0 23852.0 38944.0 46590.0 40497.0 41460.0 30504.0 40119.0 33990.0 29703.0 True False 44102.2199471622 31561.692548717932 38427.57711444245 35849.39530832456 34874.690579103255 38867.49964587974 33218.796905921845 33919.530392906054 35786.64200803971 28663.10701088958 1.538640592257045 1.1011260062186257 1.3406633516681632 1.25071560786152 1.2167100574914573 1.3560113923139367 1.1589391510592861 1.1833863781766392 1.2485262673876834 1.0 14.806907382249621 -14.522878727621658 0.09442366307798819 0.17395262731298694 1.4523455626954895 0.4138356887085114 0.1083193366656229 205.33537244426228 1.330067208453391 33.80276776955031 2.076340142059799 3.0000001219818424e-15 14.522878727621658 1.2783929353825025 QITTS(ph)PITVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QITTSPITVR 10 0 O95835;O95835-2 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 QIT(0.014)T(0.203)S(0.783)PIT(0.001)VR;QIT(0.008)T(0.081)S(0.908)PIT(0.003)VR 151.13 0.00011211 60254000.0 256120.0 281030.0 283860.0 295330.0 322380.0 246901.0 282780.0 226062.0 238834.0 206081.0 True False 299476.0573994164 308928.80113743315 290628.29894504545 278783.6175727787 259211.95322419325 233953.07691563052 255993.03125009156 220128.11203248825 242326.49542046283 243441.85396370187 1.2301748960721826 1.269004471118987 1.1938304536095887 1.1451753798027944 1.0647797369422054 0.9610224088685828 1.0515571874023812 0.9042328114429748 0.9954183780435498 1.0 17.893217700479077 -6.157238959386562 1.1205537815305342 0.9739780076122354 1.253833640953643 0.8930328068423156 0.038015072532221236 0.1394160934946368 0.36076243886128334 0.015011246671674085 0.025117567618432226 6.962433186912104e-07 6.157238959386562 0.2798556333414076 QITTS(ph)PITVR ddPTM_PC-9_Lapatinib_30min_R1 3 QITTSPITVR 10 0 O95835;O95835-2 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 QIT(0.019)T(0.217)S(0.738)PIT(0.026)VR;QIT(0.052)T(0.198)S(0.749)PITVR;QIT(0.195)T(0.075)S(0.724)PIT(0.005)VR 124.6 0.00040737 38062400.0 108417.0 132020.0 140527.0 120378.0 144258.0 127551.0 120349.0 124221.0 142250.0 109797.0 True False 106870.95369875715 131714.3158012843 128973.41250990685 129230.99968923617 135773.02806214042 122095.94106590327 126580.08234782044 129992.76115105611 126228.30704109264 128775.26515469405 0.8299028044739503 1.0228230991647322 1.0015387066372938 1.0035389912340282 1.0543408930204117 0.9481319329393957 0.9829533815811864 1.0094544243018992 0.980221682241991 1.0 16.97449598508212 -4.756815219357497 24.999996237834207 1.0002802444553411 0.8299025485686842 0.7899984324759456 0.02636133565691002 62.88276729323519 339927.41481912625 0.006608491530925149 0.051895867412004845 1.7505913598199265e-05 4.756815219357497 -0.17037769588665697 QITTSPIT(ph)VR ddPTM_PC-9_AZD4547_30min_R2 1 QITTSPITVR 10 0 O95835;O95835-2 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 QIT(0.012)T(0.038)S(0.258)PIT(0.692)VR 80.455 0.043112 38031000.0 47895.0 45824.0 68793.0 67290.0 65140.0 61197.0 60507.0 76464.0 57808.0 61729.0 True False 63124.61372211262 60635.7118628396 67880.75987145226 51777.33012013646 56096.43539824643 57370.34191579602 65892.00578240931 64648.24576791965 60863.61286262894 59567.88649884532 1.059708803389159 1.0179261918922535 1.1395529346633455 0.869215497869647 0.9417227753973413 0.9631085688579551 1.1061665883292096 1.0852868813664023 1.0217520956330848 1.0 15.8622471519308 -9.588109242076563 12.351767320644143 0.9999972856350056 1.021655969870487 0.007563726897802714 0.07720607600142934 0.0 0.0 0.07947283143925021 0.019274992846525688 2.58161073271687e-10 9.588109242076563 0.02165868423548145 QITVNDLPVGR ddPTM_PC-9_Lapatinib_30min_R1 2 QITVNDLPVGR 11 0 A0A0A0MSI0;Q06830;A0A0A0MRQ5;P32119 A0A0A0MSI0;P32119 PRDX1;PRDX2 Peroxiredoxin-1;Peroxiredoxin-2 0 ; 125.97 0.0020008 25995000.0 96614.0 82177.0 97588.0 87999.0 85799.0 92581.0 95387.0 84080.0 103492.0 86015.0 False True 95236.26664316251 81986.72420543982 89564.69134057373 94470.74001605833 80752.47150732423 88621.52644685192 100325.67212782445 87986.66374913082 91835.64114092627 100882.57814221687 0.9440308564369301 0.8126945773517102 0.887811285059666 0.9364425627870098 0.8004600298129307 0.8784621495489516 0.9944796611600535 0.8721690639695356 0.9103221074650085 1.0 16.622317525015973 -7.040973402057287 24.59698472266521 0.9340016984641489 0.8730094211617935 0.25548571184392554 0.055304208671932475 654.4067469589061 392848.8332287149 0.020597567935234182 0.01595693523832515 9.09969001091238e-08 7.040973402057287 -0.06099227730235546 QIVGT(ph)PVNSEDSDTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QIVGTPVNSEDSDTR 15 0 Q5QJE6;J3KP30 Q5QJE6 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 QIVGT(0.761)PVNS(0.238)EDS(0.001)DTR;QIVGT(0.869)PVNS(0.042)EDS(0.085)DT(0.004)R 135.69 2.4243000000000002e-06 7887800.0 41510.0 38965.0 47329.0 39793.0 52956.0 37977.0 44842.0 34355.0 37237.0 32431.0 True False 48536.8231401288 42833.18768928615 48457.50285623202 37563.52722064668 42579.651947826795 35985.419265312376 40594.241132034134 33453.21765213139 37781.520679517125 38310.48357634525 1.2669331892771458 1.118053955229462 1.2648627303193853 0.9805025599791757 1.111436034551063 0.9393099722586513 1.059611817510416 0.8732131398306605 0.9861927376673801 1.0 15.225451615929673 -5.8946301399744465 0.7634911073354015 0.9609589540434013 1.248955402525863 0.6063803607741585 0.07826787508120013 0.5634113076444628 0.618918373137455 0.03717740754937909 0.10788137334349863 1.2745881017252721e-06 5.8946301399744465 0.28799644848246164 QIVGT(ph)PVNSEDSDTR ddPTM_PC-9_Lapatinib_30min_R1 2 QIVGTPVNSEDSDTR 15 0 Q5QJE6;J3KP30 Q5QJE6 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 QIVGT(0.673)PVNS(0.316)EDS(0.009)DT(0.001)R;QIVGT(0.939)PVNS(0.061)EDSDTR 178.52 9.0402e-05 19723800.0 47623.0 44049.0 46205.0 37816.0 50468.0 45589.0 40043.0 32945.8 49913.0 37255.0 True False 46943.887287011414 43947.00724686248 42406.20325645785 40597.114790477935 47499.5714639056 43639.26474314959 42116.23060809625 34476.582142556064 44291.2723328088 43694.47711083286 1.074366610863343 1.0057794520664263 0.9705163228957461 0.9291131848883708 1.087084103179012 0.9987363993956669 0.9638799544680826 0.7890375265300642 1.013658367405614 1.0 15.415163317207796 -7.524933483964126 24.99971808450061 0.9161005238004989 1.006329076461611 0.17787743662139432 0.07152268082215393 96.21191617214062 1170540.750520252 0.0324218528263666 0.01888193279235935 2.9858398916516644e-08 7.524933483964126 0.09022855266111218 QIVGTPVNS(ph)EDSDTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QIVGTPVNSEDSDTR 15 0 Q5QJE6;J3KP30 Q5QJE6 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 QIVGT(0.195)PVNS(0.739)EDS(0.062)DT(0.004)R 110.57 0.0033534999999999997 0.0 23458.0 23325.0 17890.0 22022.0 28460.0 18602.0 28855.0 16132.0 23726.0 15611.0 True False 27428.976083380883 25640.551850445234 18316.565448202808 20788.178736287307 22883.467301819426 17626.478373050544 26121.645507890953 15708.55209326687 24072.94786481786 18441.150723391984 1.4873787701647134 1.3903986923072567 0.993244170222461 1.1272712342141533 1.2408915064498938 0.9558231282547864 1.4164867420532776 0.8518206010507303 1.3053929348498914 1.0 14.17064106195085 -5.120172946595916 4.975009217504457 1.1173601607677848 1.4651727216514572 0.39513195157940284 0.16351328594826517 0.19677576974617672 7.007253435275723 0.03833994268043784 0.11036790580593801 7.5827555118114226e-06 5.120172946595916 0.3478125608836724 QIVGTPVNSEDS(ph)DTR ddPTM_PC-9_AZD4547_30min_R2 2 QIVGTPVNSEDSDTR 15 0 Q5QJE6;J3KP30 Q5QJE6 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 QIVGT(0.009)PVNS(0.003)EDS(0.644)DT(0.344)R;QIVGT(0.017)PVNS(0.011)EDS(0.97)DT(0.002)R 174.87 7.9536e-05 19177900.0 51706.0 53397.5 71120.0 84250.0 89386.0 75503.0 57753.0 82163.0 64738.0 65035.0 True False 68147.43244838838 70657.19762997494 70176.90233101745 64827.46414952448 76976.29681467096 70781.78547426098 62892.90511761425 69466.59626791136 68159.91851475347 62758.144445113394 1.085873922037136 1.1258649893922508 1.1182118743550855 1.0329729268241967 1.2265546965301433 1.1278501953824471 1.0021473017357725 1.1068937248242736 1.0860728773516293 1.0 15.937515076670506 -9.045834235602014 0.47894866827352645 0.9941927559925994 1.1147072494733195 0.24942188142167632 0.055834527232259436 3.1419195935682747 1.3003025405781694 0.10435480999875667 0.032164777150086296 8.998409732620469e-10 9.045834235602014 0.12051449348072008 QIVGTPVNSEDS(ph)DTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QIVGTPVNSEDSDTR 15 0 Q5QJE6;J3KP30 Q5QJE6 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 QIVGTPVNS(0.014)EDS(0.967)DT(0.019)R 151.38 9.1927e-05 8662400.0 29687.0 31375.0 41593.0 35037.0 47924.0 35598.0 31901.0 31256.0 35471.0 27130.0 True False 34712.42275502295 34489.70264984864 42584.734862330886 33073.9904814866 38533.63622531251 33731.17821330254 28879.106336760648 30435.563118469458 35989.69627046089 32048.454239038154 1.0831231514666881 1.0761736710482843 1.3287609612840083 1.0319995540127875 1.2023555313433736 1.052505620449384 0.9011076203975875 0.949673356832167 1.12297760141648 1.0 14.967967154008026 -6.973557958983151 6.444880361952029 0.9873179066888709 1.1437150769892623 0.372988614689546 0.0926515848446312 0.17824947567112537 25.048441262153087 0.03290351562279686 0.028490883726046287 1.0627767404197452e-07 6.973557958983151 0.15639717030039146 QIVGTPVNSEDS(ph)DTR ddPTM_PC-9_Lapatinib_30min_R1 1 QIVGTPVNSEDSDTR 15 0 Q5QJE6;J3KP30 Q5QJE6 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 QIVGT(0.149)PVNS(0.1)EDS(0.525)DT(0.226)R 132.51 6.4902999999999995e-06 17330000.0 36572.0 31166.0 39673.0 31564.0 38848.0 33439.0 23255.0 31027.0 33950.0 29056.0 True False 36050.47657351659 31093.83704183334 36411.239082208675 33885.321854417314 36563.0370181066 32008.89192011622 24459.03011241111 32468.627689632274 30126.19349065089 34078.290885313625 1.057872200658188 0.912423605587378 1.0684584859242592 0.9943374792020608 1.0729128740979144 0.939275154022198 0.7177305397951155 0.9527657299159022 0.8840288849002715 1.0 15.056565362028907 -6.996423515807455 23.532664298853195 0.8766676426580315 1.0152711283978053 0.3726187733895756 0.0808078756238533 50.401536688350866 331626.4237965898 0.02744258335570244 0.02406467263343001 1.0082691613842482e-07 6.996423515807455 0.13860348573977377 QIVGTPVNSEDSDT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 QIVGTPVNSEDSDTR 15 0 Q5QJE6;J3KP30 Q5QJE6 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 QIVGT(0.02)PVNS(0.042)EDS(0.45)DT(0.488)R 134.37 2.8649e-05 15775000.0 23900.0 25669.0 26954.0 38463.0 41268.0 32905.0 21947.0 31923.0 30266.0 34950.0 True False 31499.702849117704 33966.002265346324 26596.57234856927 29595.949597426243 35538.650537531976 30847.445148279618 23900.240483027366 26990.033867562473 31865.798970736374 33726.41113795207 0.9339773129217218 1.0071039615337145 0.7885977621449426 0.8775303567393848 1.0537335381510726 0.9146376417610359 0.7086505701797785 0.8002640351255992 0.9448321922067194 1.0 15.041591187411926 -7.025777594753816 24.93615864823558 0.8417708998154485 0.9312216151247044 0.08133455582804028 0.0995495506929455 1455.0589050873853 1407558.8507306173 0.038466096874600605 0.029917699228077764 9.423720683107027e-08 7.025777594753816 0.08945071530925586 QIY(ph)SRY(ph)QT(ph)LELEK ddPTM_PC-9_AZD4547_30min_R2 1 QIYSRYQTLELEK 13 1 P09630-2;P09630 P09630-2 HOXC6 Homeobox protein Hox-C6 3 QIY(0.998)S(0.159)RY(0.885)QT(0.958)LELEK 65.895 0.025608999999999996 0.0 6012.8 7649.9 10327.0 19650.0 14069.0 8525.9 10189.0 10021.0 8560.1 9427.4 True False 7924.745325990582 10122.580573052039 10190.057232458072 15119.996089473663 12115.762198617263 7992.774125200342 11095.801261291565 8472.48470967151 9012.569410209495 9097.349595477239 0.8711048468369712 1.112695567738157 1.1201127455323991 1.6620221011392804 1.3317903276620955 0.8785827170117725 1.2196740539473012 0.9313135238733288 0.99068078187191 1.0 13.151230579159607 -6.755763349305881 24.99570472265232 1.0132337986375528 1.2326670638633999 0.21463642034114017 0.2049642283409463 242.20066702052569 1066586.3165693148 0.0739408861245216 0.07198988888352453 1.7548364664234688e-07 6.755763349305881 0.21943326522584705 QKDFLDGVYAFEYYPS(ph)TPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QKDFLDGVYAFEYYPSTPGR 20 1 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 1 QKDFLDGVY(0.001)AFEY(0.002)Y(0.002)PS(0.497)T(0.497)PGR 46.22 0.036529 4268900.0 34485.0 29427.0 34170.0 37298.0 48688.0 42474.0 34991.0 43802.0 40960.0 35928.0 True False 40322.629390203314 32348.318083732123 34984.74239044664 35208.313981747524 39147.93590973241 40246.58866879635 31676.399167097956 42652.24391205527 41558.96251129309 42441.46199410847 0.9500763521247387 0.762186705260591 0.8243057789880817 0.8295735426511693 0.9223983828635958 0.9482846909086968 0.7463550424227877 1.0049664151054944 0.9792066662798307 1.0 15.37318673361837 -7.7919730106409135 24.99954887414614 0.9940650872392282 0.8552419249861111 0.479495086478977 0.06683330931448743 185.89499582806673 152199.87912838362 0.03658320420332088 0.017577180095603957 1.6144588847341136e-08 7.7919730106409135 -0.13882316225311708 QKDFLDGVYAFEYYPS(ph)TPGR ddPTM_PC-9_Lapatinib_30min_R1 1 QKDFLDGVYAFEYYPSTPGR 20 1 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 1 QKDFLDGVYAFEYYPS(0.859)T(0.141)PGR 167.98 1.5777e-08 6230500.0 56457.0 41964.0 42513.0 40756.0 41717.0 41608.0 35820.0 35197.0 43019.0 35371.0 True False 55651.91282705418 41866.834936260464 39017.745244925696 43753.33219803044 39263.28807877763 39828.52283298533 37674.58433139393 36832.38111296571 38173.74720984715 41484.8302211051 1.341500315427148 1.0092082988677877 0.9405304309302852 1.0546826867757375 0.9464492892826816 0.9600743843160979 0.908153272668506 0.8878517982755902 0.9201856921286504 1.0 15.34029626141355 -4.748162643771881 3.1540537060612444 0.9508424565047934 1.4181903384102619 0.869618972991801 0.04495170457364906 0.14314578100530648 2.000537172568914 0.01239253380980667 0.17481461720879105 1.7858186585089617e-05 4.748162643771881 0.4673478819054685 QKDFLDGVYAFEYYPST(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 1 QKDFLDGVYAFEYYPSTPGR 20 1 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 1 QKDFLDGVYAFEYYPS(0.056)T(0.944)PGR 155.31 1.4702000000000001e-05 4847100.0 53049.0 44402.0 48536.0 42420.0 51054.0 43535.0 38001.0 34105.0 43958.0 42616.0 True False 52292.511532004864 44299.189897050725 44545.55743437804 45539.70830897168 48051.104096025905 41673.1095350417 39968.50583967898 35689.64280642374 39006.9871417388 49982.11881774939 1.0462243852182398 0.8863007600494004 0.8912298735634884 0.9111200042363923 0.9613658890939663 0.83376036312096 0.7996560927202144 0.7140482166544292 0.7804188390646385 1.0 15.609124440299142 -6.888029377414498 4.5350382006282315 0.8017278435279119 0.9317899953999962 0.3135537007993061 0.08108362352822532 0.23495825740033238 8.270019699777874 0.028446821023799685 0.025011623219292116 1.294108299831631e-07 6.888029377414498 0.13006215187208425 QKEDVEVVGGS(ph)DGEGAIGLSSDPK ddPTM_PC-9_AZD4547_30min_R2 2 QKEDVEVVGGSDGEGAIGLSSDPK 24 1 Q8NHZ8 Q8NHZ8 CDC26 Anaphase-promoting complex subunit CDC26 1 QKEDVEVVGGS(1)DGEGAIGLSSDPK;QKEDVEVVGGS(0.998)DGEGAIGLS(0.001)S(0.001)DPK 81.847 4.0471e-05 42590000.0 339380.0 303810.0 379280.0 462560.0 456860.0 455870.0 376690.0 437040.0 417400.0 391260.0 True False 447295.7804574724 402010.6411716418 374250.49938285025 355923.93848076 393432.87497763056 427364.3768347122 410214.6802547774 369505.5101801061 439462.91186101106 377562.1064902754 1.1846945781064315 1.064753676974191 0.9912289738549002 0.9426897783502204 1.0420348552318608 1.1319048429075325 1.0864826559742244 0.9786615336346609 1.1639486704482882 1.0 18.526354452267263 -6.554687129535896 24.793639994721307 1.073448726251881 1.0369254384286652 0.02488444837919279 0.07728856582837426 675.9058076341389 526842.9642797105 0.02631206597429875 0.02631223281983363 2.7881290437562395e-07 6.554687129535896 -0.03652328782321579 QKEDVEVVGGS(ph)DGEGAIGLSSDPK ddPTM_PC-9_Lapatinib_30min_R1 4 QKEDVEVVGGSDGEGAIGLSSDPK 24 1 Q8NHZ8 Q8NHZ8 CDC26 Anaphase-promoting complex subunit CDC26 1 QKEDVEVVGGS(0.958)DGEGAIGLS(0.02)S(0.022)DPK;QKEDVEVVGGS(0.959)DGEGAIGLS(0.021)S(0.021)DPK;QKEDVEVVGGS(1)DGEGAIGLSSDPK;QKEDVEVVGGS(0.961)DGEGAIGLS(0.021)S(0.018)DPK 111.23 2.2156999999999997e-07 59102900.0 466886.0 391180.0 388908.0 422267.0 423746.0 427968.0 389192.0 420723.0 401455.0 371394.0 True False 460228.1200235943 390274.24674402823 356933.4854682934 453321.9238214173 398822.09339669 409664.8062821343 409342.457428919 440271.3265048241 356238.91039143613 435588.9580486008 1.0565651665858902 0.8959691000718237 0.8194273038217571 1.0407103197754566 0.9155927532767978 0.9404848279841519 0.9397447980838086 1.010749511367781 0.8178327384315578 1.0 18.732607857393297 -5.775544520672059 24.999934912696673 0.9500798263822734 0.9211853199766389 0.02512429694233187 0.07910911334879255 1074.2520937403765 1903999.9533510038 0.021733237305693858 0.03240809977764572 1.6767004439562227e-06 5.775544520672059 -0.028894506405634512 QKEENNTDLPYLEESTLTTAALS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QKEENNTDLPYLEESTLTTAALSPSK 26 1 A0A087WU78;A0A087WWC4;Q6T4R5-4;Q6T4R5-3;Q6T4R5-2;Q6T4R5 A0A087WU78 NHS Nance-Horan syndrome protein 1 QKEENNTDLPYLEES(0.003)T(0.003)LT(0.003)T(0.006)AALS(0.762)PS(0.224)K 73.227 0.0013743 0.0 10027.0 9943.8 6489.1 10285.0 19777.0 14857.0 14864.0 15768.0 10534.0 8698.5 True False 11724.373057722749 10930.954747715221 6643.82475404879 9708.76479441989 15901.838820382387 14077.872765746277 13455.974313959141 15354.106707576992 10688.039821629925 10275.469192711882 1.1410061027713008 1.0637913016632135 0.6465714245692137 0.9448488056687533 1.5475535493465487 1.3700467104442626 1.3095240773533832 1.494248721845933 1.0401510258247544 1.0 13.326916650492345 -6.234701383795069 22.70998445615031 1.3229195377295757 0.935643698371155 0.4057091624421384 0.2021614828837609 217.8981756112334 185071.44671511036 0.05921228389881539 0.07640549296074305 5.825036033041169e-07 6.234701383795069 -0.3872758393584207 QKFNDS(ph)EGDDTEETEDYR ddPTM_PC-9_Lapatinib_30min_R1 2 QKFNDSEGDDTEETEDYR 18 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 QKFNDS(0.976)EGDDT(0.009)EET(0.015)EDY(0.001)R;QKFNDS(0.914)EGDDT(0.083)EET(0.003)EDYR 51.786 0.028125999999999998 14067300.0 36085.0 34203.0 41552.0 30460.0 39452.0 34388.0 33502.0 30444.8 34681.0 34457.0 True False 35570.42128282145 34123.805054926044 38135.754955358454 32700.130011581266 37131.51092561633 32917.30540234326 35236.569633455045 31859.376552206668 30774.86057287963 40412.84653893351 0.8801760907525558 0.8443801409052283 0.9436542639632841 0.8091518616506794 0.9188046402483437 0.8145257813163672 0.8719150629369384 0.7883477478260167 0.7615118262761149 1.0 15.302526353020076 -6.780612241945133 24.986570511029754 0.8355727572712716 0.876982642426512 0.03677861255260484 0.06955832603756955 665.9066365813518 867821.3916818751 0.023199398382412195 0.02049109248145712 1.6572489710853171e-07 6.780612241945133 0.04140988515524047 QKGS(ph)EENLDEAR ddPTM_PC-9_AZD4547_30min_R2 1 QKGSEENLDEAR 12 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;H0YG19 P35611 ADD1 Alpha-adducin 1 QKGS(1)EENLDEAR 62.035 0.025169999999999998 3048700.0 14066.0 14960.0 21100.0 24526.0 20207.0 22223.0 21731.0 28092.0 19421.0 19749.0 True False 18538.69540902466 19795.527441255246 20820.200213504904 18871.9096229227 17401.606848209474 20833.39229692198 23665.016901474813 23751.026889940327 20447.554411242683 19057.59352112776 0.9727721072690613 1.038721254040254 1.0924884188773925 0.9902566975206388 0.9131062024655728 1.093180640767971 1.2417631258237898 1.2462762868569581 1.0729347537281648 1.0 14.218078335401408 -6.996065009446556 24.639328630922293 1.161724474892832 1.0074893397013258 0.3857779227559093 0.08136603568274403 89.60259972499485 561048.8587469138 0.028772297745791136 0.02526129632990222 1.0091018225382518e-07 6.996065009446556 -0.1542351351915061 QKGS(ph)EENLDEAR ddPTM_PC-9_Lapatinib_30min_R1 1 QKGSEENLDEAR 12 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;H0YG19 P35611 ADD1 Alpha-adducin 1 QKGS(1)EENLDEAR 98.58200000000001 0.017777 0.0 9099.5 12244.0 8634.6 9734.6 8656.1 9562.9 8716.3 9851.8 9871.5 6514.9 True False 8969.739461356075 12215.649770269121 7924.6965185198815 10450.51495767364 8146.965216547379 9153.917059208692 9167.587364816553 10309.55059376411 8759.667718496625 7640.991784441417 1.1738972785732154 1.5986995032690154 1.03712930756661 1.3676909035490619 1.06621829291012 1.1980011649597495 1.1997902397282496 1.3492424654553892 1.1464045461131178 1.0 12.899544193817233 -14.52287874527932 0.09184028831209476 0.28515514742018755 1.4200312567459306 0.19209674955103984 0.15449972126627678 352.1755350502972 2.230656555346514 50.06366539341169 3.309872332718357 3.000000000007032e-15 14.52287874527932 1.134876109325743 QKNS(ph)PLLSVSSQTITK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QKNSPLLSVSSQTITK 16 1 Q8ND24;E9PRE9 Q8ND24 RNF214 RING finger protein 214 1 QKNS(1)PLLSVSSQTITK 111.38 0.00021972 7056400.0 47761.0 40070.0 45168.0 51676.0 61749.0 51994.0 52627.0 47075.0 43668.0 39053.0 True False 55845.99397725102 44047.88478659554 46244.976420593885 48780.76125585247 49649.72671890545 49267.343109794165 47641.78957351505 45839.3311300854 44306.561888260454 46132.999756622085 1.2105433046164464 0.9548020943570391 1.0024272573767703 1.0573940891162257 1.0762301818835998 1.0679414599030528 1.0327052180619665 0.9936343045523603 0.9604092975094373 1.0 15.493511484944477 -7.715352390368062 2.788829227184551 0.9794890771645675 1.0543099473287028 0.23070698171315585 0.06207948412870053 0.43577363413681386 6.827231736880572 0.03663432482418623 0.017324590114780082 1.9259615368523777e-08 7.715352390368062 0.0748208701641353 QKS(ph)AEPSPT(ph)VMSTSLGSNLSELDR ddPTM_PC-9_AZD4547_30min_R2 1 QKSAEPSPTVMSTSLGSNLSELDR 24 1 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 2 QKS(0.818)AEPS(0.529)PT(0.632)VMS(0.018)T(0.002)S(0.001)LGSNLSELDR 48.373999999999995 0.030223000000000003 9214900.0 20158.0 22399.0 26872.0 32745.0 29351.0 26853.0 22251.0 26736.0 23671.0 22256.0 True False 26567.82468755293 29639.038713681573 26515.6597221471 25196.14615520687 25276.12028513862 25173.87766499782 24231.29589410134 22604.565532160213 24922.20073469573 21476.824214199176 1.2370462421528734 1.380047553496575 1.2346173464797718 1.1731783947157655 1.1769021356717897 1.1721415333070695 1.1282532115749717 1.0525096870334973 1.1604229976524498 1.0 14.390493056804004 -4.599693297097219 0.18029761701255556 0.976659865735751 1.638956421504723 0.7275546579930074 0.05150495375766257 9.306894099656256 0.2850850250857306 0.1442017139520631 1.4323621933114041 2.513660976177044e-05 4.599693297097219 0.662296555768972 QKS(ph)AEPSPT(ph)VMSTSLGSNLSELDR ddPTM_PC-9_Lapatinib_30min_R1 1 QKSAEPSPTVMSTSLGSNLSELDR 24 1 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 2 QKS(0.856)AEPS(0.53)PT(0.583)VMS(0.013)T(0.013)S(0.003)LGS(0.001)NLS(0.001)ELDR 47.018 0.035653 5231800.0 8920.0 7543.7 11543.0 10060.0 11038.0 12204.0 8551.6 10651.0 9932.9 9249.0 True False 8792.799164272335 7526.233026133544 10593.979097268544 10799.845959176224 10388.76654154296 11682.063368913494 8994.360004699845 11145.884343387152 8814.152203925963 10847.677326482164 0.8105697560533713 0.6938105549802757 0.976612668170515 0.9955906351317096 0.9576950188388369 1.0769184054170162 0.8291507696990709 1.0274904025930953 0.8125381995285013 1.0 13.405098549566324 -5.268698036367869 24.975933376497803 0.9612440605316834 0.7521901518835418 0.5061150229598108 0.08190119990357567 364.56442642774124 1254413.9098992115 0.02006909888010162 0.04317503312474298 5.386441699987954e-06 5.268698036367869 -0.20905390864814166 QKS(ph)AEPSPTVMSTSLGSNLSELDR ddPTM_PC-9_Lapatinib_30min_R1 1 QKSAEPSPTVMSTSLGSNLSELDR 24 1 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 QKS(0.993)AEPS(0.007)PTVMSTSLGSNLSELDR 64.415 0.006031399999999999 0.0 7964.8 7664.2 9457.1 10991.0 11426.0 8012.5 8709.8 7835.5 13886.0 9356.9 True False 7851.2204914345675 7646.454015787042 8679.573743461691 11799.314804901172 10753.945144380308 7669.824053049766 9160.7508266213 8199.565934899076 12322.012453937505 10974.227697714461 0.7154235093071466 0.6967646586537953 0.7909051992122722 1.0751840703431501 0.9799272842334017 0.6988941968688253 0.8347512990393992 0.7471656467094037 1.1228136314780255 1.0 13.421831794400576 -5.529932796441645 24.959226315756073 0.9039629396903452 0.7155292617008401 0.3184868645769461 0.12805739047562278 211.1360417304445 747056.7701977544 0.03597944927269887 0.0624904816696469 2.951665937759106e-06 5.529932796441645 -0.18843367798950517 QKS(ph)DAEEDGGTVSQEEEDR ddPTM_PC-9_Lapatinib_30min_R1 1 QKSDAEEDGGTVSQEEEDR 19 1 P27824;P27824-2;P27824-3 P27824 CANX Calnexin 1 QKS(1)DAEEDGGTVSQEEEDR 151.39 3.0576e-05 19795000.0 28187.0 66023.0 28497.0 32350.0 40275.0 22621.0 47881.0 32630.0 40224.0 23127.0 True False 27785.04821113728 65870.12779994105 26154.08666160111 34729.12691643647 37906.10368369657 21653.552562126522 50360.04389646771 34146.108921671475 35693.549542501976 27124.47113520956 1.0243535467524838 2.428439156346786 0.9642247596728691 1.2803614397980099 1.3974872908947398 0.7983032168328111 1.856627679317097 1.2588672697602319 1.3159168842252236 1.0 14.727307388146246 -1.5228787453204555 0.03484513638907544 0.0003404289192296473 3.4305768165217034 0.05820059152240342 0.44630078535238876 2996.431332790858 8.010949630952094 233.88027700819828 652.0776778352648 0.02999999999722875 1.5228787453204555 3.430236387602474 QKS(ph)DAEEDGGTVSQEEEDRKPK ddPTM_PC-9_AZD4547_30min_R2 1 QKSDAEEDGGTVSQEEEDRKPK 22 3 P27824;P27824-2;P27824-3 P27824 CANX Calnexin 1 QKS(1)DAEEDGGTVSQEEEDRKPK 67.153 0.0021197 12899000.0 48326.0 46728.0 53101.0 36041.0 47517.0 29688.0 54083.0 33683.0 42917.0 37032.0 True False 63692.66275675575 61831.9121841561 52396.84604442297 27732.30427789926 40920.084753123665 27831.604666832576 58896.2822273463 28478.06630833904 45185.50500320801 35735.52095166353 1.782334804714545 1.7302647488416634 1.4662398825889744 0.7760430949197703 1.1450815229046993 0.7788218535970995 1.6481159546270616 0.7969120233858897 1.264442319571238 1.0 15.125071199553656 -5.546248583642027 4.732509811204909 1.0666602620977692 1.7286030791638354 0.5606901786587468 0.25183877202989535 0.1300904640791085 7.37332661233719 0.06577176778133434 0.12347636323923686 2.842833446478447e-06 5.546248583642027 0.6619428170660662 QKS(ph)DAEEDGGTVSQEEEDRKPK ddPTM_PC-9_Lapatinib_30min_R1 1 QKSDAEEDGGTVSQEEEDRKPK 22 3 P27824;P27824-2;P27824-3 P27824 CANX Calnexin 1 QKS(1)DAEEDGGTVSQEEEDRKPK 69.081 0.0017525 19046000.0 33414.0 39050.0 13628.0 10347.0 14225.0 15036.0 14311.0 13921.0 13222.0 5308.0 True False 32937.51023262286 38959.58212422487 12507.558445601291 11107.952896580155 13388.31346742604 14392.94533062793 15051.953555739208 14567.820481109055 11732.799126167487 6225.480727534581 5.290757722041297 6.258084127047594 2.0090911839597876 1.7842723128915914 2.1505670089397397 2.3119411914600585 2.4177977917699045 2.3400314158354503 1.8846414662043163 1.0 12.603969530108186 -5.265500135751044 24.99800879154497 2.0607012151426636 5.774421093945328 0.9204416036119397 0.44494522199204684 72.23034758127093 444652.54616787564 0.11009617058162378 0.2432335135125813 5.426250817161465e-06 5.265500135751044 3.7137198788026646 QKS(ph)KS(ph)SQS(ph)S(ph)T(ph)LSHSNR ddPTM_PC-9_Lapatinib_30min_R1 1 QKSKSSQSSTLSHSNR 16 2 Q13835-2;Q13835 Q13835-2 PKP1 Plakophilin-1 5 QKS(0.911)KS(0.625)S(0.625)QS(0.897)S(0.914)T(0.822)LS(0.2)HS(0.007)NR 50.088 0.044347000000000004 0.0 7387.0 6040.3 8394.1 7297.6 6759.7 6886.6 7653.0 7093.7 9366.9 7589.4 True False 7281.660025390107 6026.314056464928 7703.969500163032 7834.289848079957 6362.10773608153 6592.076171448681 8049.234893583413 7423.299198825037 8311.901084170191 8901.217677760165 0.8180521237654317 0.6770213104125934 0.8654961353671332 0.8801368679763956 0.7147457759602215 0.7405813912313467 0.9042846928341676 0.8339644605447937 0.9337937105995744 1.0 13.11978699349399 -8.207922301142862 0.9084248900377292 0.9985209660964962 0.7858077473923052 0.5215745823323035 0.06682594678681943 0.45836177531200123 0.7803043082465392 0.06514371768320522 0.02382852918312043 6.195519080974041e-09 8.207922301142862 -0.21271321870419102 QKS(ph)PAQSDSTTQR ddPTM_PC-9_AZD4547_30min_R2 3 QKSPAQSDSTTQR 13 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 QKS(0.999)PAQS(0.001)DSTTQR;QKS(0.999)PAQS(0.001)DSTTQR;QKS(0.996)PAQS(0.003)DSTTQR 83.823 0.0042279 101178000.0 9812.2 9262.3 9826.099999999999 14026.599999999999 13143.800000000001 10603.5 9386.3 11485.5 7288.5 10776.400000000001 True False 12932.275493561205 12256.157340851494 9695.799493740307 10792.98407880973 11319.010248502782 9940.461468767147 10221.662516327508 9710.679885533593 7673.755230232343 10399.121516080875 1.2435930740460277 1.1785762212605129 0.9323671695486034 1.0378745995149492 1.0884583116948312 0.9558943467864598 0.9829351931815634 0.9337980973217115 0.7379234119310837 1.0 13.344174038884628 -1.522878745283001 0.345838346477583 0.907559231114748 4.848938516290142 0.5804499614327623 0.08678770525476 45.20328737478899 0.6382177249665288 0.07676705966369192 115.70548652926404 0.029999999999816014 1.522878745283001 3.941379285175394 QKS(ph)PAQSDSTTQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QKSPAQSDSTTQR 13 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 QKS(0.989)PAQS(0.009)DS(0.002)TTQR;QKS(0.58)PAQS(0.025)DS(0.336)T(0.046)T(0.012)QR;QKS(0.986)PAQS(0.012)DS(0.001)T(0.001)TQR 93.228 0.020395 38806600.0 20671.5 20415.7 17328.2 21356.0 24412.2 18179.2 23536.5 21699.3 16988.7 16874.1 True False 24170.77666926455 22442.435773339126 17741.370005564444 20159.492557086174 19628.80465444402 17225.85074934742 21306.95233049644 21129.71636730881 17237.127598037237 19933.240754697883 1.2125864011133243 1.1258799333996843 0.8900394182708671 1.011350477585285 0.9847272150073181 0.8641771281113744 1.0689156165173392 1.060024138941328 0.8647428589340034 1.0 14.282888662764295 -5.069693303432321 4.5619109305785885 0.9726489267817585 1.1966540243875416 0.5748726956146331 0.07079937624617366 0.13805150544265896 5.422027734023331 0.01806154289347228 0.05605047200929039 8.51739319868338e-06 5.069693303432321 0.22400509760578313 QKS(ph)PAQSDSTTQR ddPTM_PC-9_Lapatinib_30min_R1 4 QKSPAQSDSTTQR 13 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 QKS(0.977)PAQS(0.005)DS(0.005)T(0.012)T(0.001)QR;QKS(0.989)PAQS(0.01)DSTTQR;QKS(0.823)PAQS(0.14)DS(0.024)T(0.01)T(0.002)QR;QKS(0.999)PAQS(0.001)DSTTQR 130.01 0.00041401 36410100.0 8385.0 9079.8 6630.65 7250.5 9047.599999999999 8941.52 8730.599999999999 11579.88 9924.900000000001 5026.76 True False 8265.428362379322 9058.776280961252 6085.503552049174 7783.725956958966 8515.437956265992 8559.11203330116 9182.627748846116 12117.923499230308 8807.0532481697 5895.628768263325 1.401958754064169 1.5365242007307893 1.0322060277621212 1.3202537444113562 1.4443646794902225 1.4517725538242154 1.5575315390068298 2.0554081634960006 1.4938276466080807 1.0 12.525429969365254 -6.8791074217264905 1.8724032295265305 1.6074221500114905 1.3272898973991658 0.06367635334195598 0.27015450066923063 0.6221196503848289 4.469605682217155 0.11494119303532774 0.09660905020855307 1.320968855210931e-07 6.8791074217264905 -0.28013225261232466 QKS(ph)PEIHR ddPTM_PC-9_AZD4547_30min_R2 1 QKSPEIHR 8 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 QKS(1)PEIHR 57.163999999999994 0.039002999999999996 382600000.0 42882.0 38120.0 48894.0 49391.0 46105.0 48552.0 44274.0 43666.0 43910.0 44551.0 True False 56517.58399899018 50441.54452277073 48245.6336132279 38004.668033343165 39704.11658022954 45516.035764755296 48214.30022989717 36918.42304485741 46230.9929559583 42991.283050269034 1.3146289198418446 1.1732970254409534 1.1222189753400715 0.8840086951790879 0.9235387679359125 1.0587270845472119 1.1214901442583358 0.858742061773064 1.075357367257477 1.0 15.391756546922032 -5.222712072768129 1.853292209371906 0.9905388633765568 1.2988748852869003 0.5999723839436406 0.08457215679086248 0.29261817094649517 1.728585612543935 0.024482448056982253 0.11389555252063557 5.988084596971556e-06 5.222712072768129 0.3083360219103435 QKS(ph)PEIHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 QKSPEIHR 8 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 QKS(1)PEIHR;QKS(1)PEIHR;QKS(1)PEIHR;QKS(1)PEIHR;QKS(1)PEIHR;QKS(1)PEIHR 71.03 0.017232 773051700.0 236772.7 271211.4 248463.5 281088.0 264552.9 206692.2 238109.9 218306.4 200332.2 189658.1 True False 276853.6416360093 298135.4754182994 254387.81214307135 265339.550659591 212715.65835388287 195852.89717117723 215554.40650560946 212576.08831474997 203261.67943371265 224041.61219730673 1.2357241983787932 1.330714738634091 1.1354489447212137 1.1843315536665322 0.9494470972050967 0.8741808954610425 0.9621177262185435 0.9488241324006389 0.9072496731308386 1.0 17.773407189466084 -6.098589384988589 1.755726333397531 0.9307182961022847 1.2563952647246388 0.8630891572796413 0.05493476107957874 0.11828754100714631 0.7256227338174919 0.018421309963238347 0.02791244045370468 7.969124559441857e-07 6.098589384988589 0.32567696862235407 QKS(ph)PEIHR ddPTM_PC-9_Lapatinib_30min_R1 2 QKSPEIHR 8 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 QKS(1)PEIHR;QKS(1)PEIHR 62.466 0.029176 473350000.0 98776.0 98108.0 108511.0 94818.0 101478.0 84895.0 75808.0 96871.0 82738.0 68221.0 True False 97367.43612669998 97880.83695373735 99589.64444457313 101791.23202357575 95509.26355342426 81264.23874991079 79732.9673086073 101371.98030497204 73419.17517023493 80012.90895123164 1.2168965908494345 1.2233130658128717 1.244669713299308 1.2721851180991073 1.1936731810567935 1.0156390989289221 0.9965012940250058 1.266945317120752 0.9175916253086657 1.0 16.28794515676833 -6.644748093043877 4.771186003101402 1.0538773648476256 1.2377702453842947 0.5528015933252532 0.08593237505260579 0.17389369126591028 6.511073208651332 0.02818553823510961 0.028034317982222792 2.265958266576444e-07 6.644748093043877 0.18389288053666908 QKS(ph)YTLVVAK ddPTM_PC-9_AZD4547_30min_R2 2 QKSYTLVVAK 10 1 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;E9PJP4;E9PQN0;E9PRG1;E9PIG0;E9PQD2;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 QKS(0.984)YT(0.016)LVVAK;QKS(0.971)YT(0.029)LVVAK 120.87 0.0032323 20613100.0 22462.0 31624.0 40506.0 46749.0 59062.0 45694.0 38826.0 46139.0 35272.0 42554.0 True False 29604.4487613758 41845.839558974345 39968.86397384979 35971.74031485009 50862.260784329614 42836.74695655643 42281.43878407168 39009.27771874403 37136.40591078484 41064.19741242956 0.7209308991003182 1.019034638341871 0.9733263156813037 0.8759879062913803 1.238603552225626 1.0431653278481061 1.0296424001525397 0.94995836219452 0.9043499751816448 1.0 15.325593480853676 -4.759932012939357 24.987188749865503 1.006652805888566 0.7209305468158774 0.450542188070432 0.09366136406354576 37.0035673023732 613190.7642483626 0.02416505497977605 0.14812950899353525 1.7380728957995708e-05 4.759932012939357 -0.28572225907268856 QKS(ph)YTLVVAK ddPTM_PC-9_Lapatinib_30min_R1 2 QKSYTLVVAK 10 1 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;E9PJP4;E9PQN0;E9PRG1;E9PIG0;E9PQD2;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 QKS(0.986)YT(0.014)LVVAK;QKS(0.982)YT(0.018)LVVAK 131.13 0.00091698 14829600.0 38429.0 32599.0 26416.0 25283.0 25340.0 21245.8 19835.9 20118.0 27021.0 22913.0 True False 37880.9954129845 32523.5190183766 24244.17844870881 27142.39616161553 23849.55102035681 20337.16666037875 20862.905844195888 21052.755724369796 23977.610436255607 26873.48152034664 1.4096050556123059 1.2102458326343821 0.9021599389849391 1.0100066915805193 0.8874752979921737 0.75677454166037 0.7763380352635001 0.7834026160112595 0.8922405687592622 1.0 14.713895617415938 -4.577699354477605 0.8079321999044551 0.8325049706582158 1.9494905823279738 0.8280108909045327 0.08171100539842918 1.2490504076843405 0.5012809387069982 0.030602769110635832 1.3520469756868112 2.6442386295262863e-05 4.577699354477605 1.116985611669758 QKSDAEEDGGTVS(ph)QEEEDRKPK ddPTM_PC-9_AZD4547_30min_R2 1 QKSDAEEDGGTVSQEEEDRKPK 22 3 P27824;P27824-2;P27824-3 P27824 CANX Calnexin 1 QKSDAEEDGGT(0.166)VS(0.834)QEEEDRKPK 55.986000000000004 0.010306000000000001 19933000.0 21952.0 18546.0 19830.0 16440.0 23026.0 13688.0 24323.0 16277.0 18756.0 20488.0 True False 28932.27937003482 24540.631813203185 19567.041243308173 12650.011995468038 19829.237357691465 12832.087196160204 26487.699880105472 13761.76365824999 19747.403868867084 19770.721356061855 1.463390174236812 1.2412613263440102 0.9896978916911784 0.6398356320766944 1.002959730228137 0.6490449673059495 1.3397437252325717 0.6960678576368954 0.9988206051375247 1.0 14.271077889859233 -5.1215404312027974 2.3879566816908206 0.8986727370183292 1.4510393148006613 0.45321494699731335 0.20029366368443424 0.2843302235547993 2.8959489814796866 0.05150371311121517 0.2360890609378381 7.558916863554429e-06 5.1215404312027974 0.5523665777823321 QKSPAQSDST(ph)TQR ddPTM_PC-9_AZD4547_30min_R2 1 QKSPAQSDSTTQR 13 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 QKS(0.034)PAQS(0.003)DS(0.01)T(0.74)T(0.214)QR 102.06 0.019008 3438300.0 9034.6 8394.9 9989.1 10764.0 10898.0 10994.0 8644.8 11260.0 7984.2 10161.0 True False 11907.414868645981 11108.387253782998 9856.638007238007 8282.52610214221 9385.000813173008 10306.543442035747 9414.17045280334 9520.025729059094 8406.228511932644 9805.266482767696 1.214389725110757 1.13290008724449 1.0052391767791924 0.8447017851782375 0.9571387814565483 1.0511232366962204 0.9601136765990308 0.970909433801733 0.8573177003099511 1.0 13.259341124477078 -5.212869692847389 2.607958040662803 0.9513451290030907 1.2011339056673809 0.7009233965137593 0.05864946278213642 0.1655633657824425 2.1383176254107292 0.0164564861061036 0.058143952858810743 6.125341509278995e-06 5.212869692847389 0.24978877666429022 QKVDSLLENLEK ddPTM_PC-9_AZD4547_30min_R2 2 QKVDSLLENLEK 12 1 B4DY08;B2R5W2;G3V4W0;G3V576;G3V5V7;B7ZW38;P0DMR1;A0A0G2JPF8;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3;A0A0G2JNQ3;B2RXH8;O60812 B4DY08;P07910-2;A0A0G2JNQ3 HNRNPC;HNRNPCL3;HNRNPCL4;HNRNPCL2;HNRNPCL1 Heterogeneous nuclear ribonucleoprotein C-like 3;Heterogeneous nuclear ribonucleoprotein C-like 4;Heterogeneous nuclear ribonucleoproteins C1/C2;Heterogeneous nuclear ribonucleoprotein C-like 2;Heterogeneous nuclear ribonucleoprotein C-like 1 0 ; 143.94 0.00011755 6538100.0 49775.0 51313.0 59312.0 70283.0 70050.0 70629.0 61085.0 67040.0 61800.0 59144.0 False True 65602.4146156835 67898.92376959434 58525.48412622763 54080.34021152556 60324.76665101568 66212.55746475741 66521.44666267489 56680.50842594339 65066.62183279948 57073.386562032545 1.1494396700006726 1.1896774987374479 1.0254426388841815 0.9475579332014253 1.0569684100565724 1.1601301666721946 1.1655423073655062 0.9931162638183011 1.1400518832377182 1.0 15.800530550261264 -9.303521782705735 0.00906720788449301 2.7495442510003327e-06 2.1125085249791713 0.08683321676460476 0.07944357925937022 11668.36481502857 36.58117637220692 4381.37025017121 4139.197933149019 4.971394383090144e-10 9.303521782705735 2.1125057754349204 QKVDSLLENLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QKVDSLLENLEK 12 1 B4DY08;B2R5W2;G3V4W0;G3V576;G3V5V7;B7ZW38;P0DMR1;A0A0G2JPF8;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3;A0A0G2JNQ3;B2RXH8;O60812 B4DY08;P07910-2;A0A0G2JNQ3 HNRNPC;HNRNPCL3;HNRNPCL4;HNRNPCL2;HNRNPCL1 Heterogeneous nuclear ribonucleoprotein C-like 3;Heterogeneous nuclear ribonucleoprotein C-like 4;Heterogeneous nuclear ribonucleoproteins C1/C2;Heterogeneous nuclear ribonucleoprotein C-like 2;Heterogeneous nuclear ribonucleoprotein C-like 1 0 ; 161.87 0.00084407 5452900.0 61603.0 53523.0 57245.0 69400.0 73513.0 56175.0 70116.0 63465.0 59674.0 60209.0 False True 72031.17118528925 58836.40971881587 58609.93790287146 65511.74299783577 59108.655367485975 53229.08410956428 63474.10488411993 61799.110996725845 60546.61935788341 71124.41508581833 1.0127488724986606 0.8272322471520389 0.824048082956507 0.9210865624524245 0.8310599854658319 0.7483939803981285 0.8924376363240728 0.8688874407214369 0.8512775716303354 1.0 16.118057262557294 -10.815766632867321 3.2400906891365677 1.000715012170791 0.8601371489104847 0.2727363209445097 0.06627270996904495 21336893.75664695 30219110.66868297 149013.30996468785 0.016048745530344966 1.5283871128930412e-11 10.815766632867321 -0.1405778632603064 QKVDSLLENLEK ddPTM_PC-9_Lapatinib_30min_R1 2 QKVDSLLENLEK 12 1 B4DY08;B2R5W2;G3V4W0;G3V576;G3V5V7;B7ZW38;P0DMR1;A0A0G2JPF8;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3;A0A0G2JNQ3;B2RXH8;O60812 B4DY08;P07910-2;A0A0G2JNQ3 HNRNPC;HNRNPCL3;HNRNPCL4;HNRNPCL2;HNRNPCL1 Heterogeneous nuclear ribonucleoprotein C-like 3;Heterogeneous nuclear ribonucleoprotein C-like 4;Heterogeneous nuclear ribonucleoproteins C1/C2;Heterogeneous nuclear ribonucleoprotein C-like 2;Heterogeneous nuclear ribonucleoprotein C-like 1 0 ; 118.73 0.00074058 6528800.0 50369.0 44735.0 47933.0 44567.0 46845.0 44348.0 44722.0 42295.0 45057.0 46701.0 False True 49650.72882345667 44631.41885601019 43992.13376673076 47844.60585115372 44089.66920081356 42451.3394202373 47037.486333573404 44260.18010548869 39982.20618875575 54773.20562482905 0.9064784187279643 0.8148403648622399 0.8031688718030563 0.873503847462699 0.8049495861682309 0.7750384323132228 0.8587681841329187 0.8080626211408971 0.7299592151428063 1.0 15.741182696719054 -4.7580292308542385 24.17000444304628 0.8227613988308619 0.9064786007055216 0.09314024379450214 0.06866910496459494 135.9008063956506 962979.8190762461 0.015731078707195548 0.10997294157738631 1.7457046516450928e-05 4.7580292308542385 0.0837172018746597 QLAEAHAQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLAEAHAQAK 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 69.672 0.031702 1522100.0 23488.0 18289.0 22371.0 25869.0 30845.0 24502.0 29598.0 22938.0 24435.0 22984.0 False True 27464.054490853887 20104.611052209777 22904.40948248994 24419.643798429588 24801.14367268519 23217.071986694147 26794.263169036753 22335.901804819958 24792.315648521642 27150.81725875612 1.011536935669837 0.7404790382774226 0.8435992649577899 0.8994073204391028 0.9134584582232728 0.855115032649953 0.9868676479856465 0.8226603859453492 0.9131333105829857 1.0 14.728708004371322 -14.522878204104742 0.1874435929953202 1.499582273767234 0.8609962471282754 0.17001884414205115 0.0745409929781459 229.72007646936675 2.232157494185243 42.740635337104244 0.20243677599874454 3.0000037383109036e-15 14.522878204104742 -0.6385860266389586 QLAEAHAQAK ddPTM_PC-9_Lapatinib_30min_R1 1 QLAEAHAQAK 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 111.63 0.0013158 2159400.0 51526.0 42845.0 54712.0 41157.0 49002.0 50530.0 48059.0 50873.0 49838.0 46585.0 False True 50791.22979128888 42745.79503488896 50213.790554427505 44183.82307572722 46119.798701638734 48368.94969118315 50547.25986550699 53236.74530101727 44224.7196225938 54637.15517938933 0.9296097065179697 0.7823576263175187 0.9190410882404353 0.8086772257936774 0.8441105425458977 0.8852757712654351 0.9251444314687679 0.9743689093296656 0.8094257374380394 1.0 15.737594747594851 -7.053967706495971 3.2207374673404714 0.924744634518526 0.8537319185490914 0.22003023121641196 0.062222202258670964 0.3866304121761041 7.970964450477595 0.02355288273453232 0.01846305745866831 8.831455673929443e-08 7.053967706495971 -0.07101271596943459 QLAEDFLR ddPTM_PC-9_Lapatinib_30min_R1 2 QLAEDFLR 8 0 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 ; 129.42 0.01744 7486600.0 47623.0 40748.0 42884.0 45020.0 48204.0 45543.0 38217.0 30394.0 47001.0 34222.0 False True 46943.887287011414 40653.65050954966 39358.243057027146 48330.920982317424 45368.73549271036 43595.23205591832 40195.689262782835 31806.216198752158 41707.2524375282 40137.22710205135 1.169584714152119 1.012866444564924 0.9805919815276828 1.2041420016244049 1.1303405533560547 1.086154555347702 1.0014565570407452 0.7924368097946306 1.0391164375028938 1.0 15.292653330472637 -7.413862442904722 3.9067893294936127 0.9308711843356663 1.0940764211982015 0.38685748001358833 0.0867148220013377 0.2350777208725219 6.3100453070011815 0.03926862629529638 0.025111059358810268 3.856004722304325e-08 7.413862442904722 0.16320523686253519 QLAEPAS(ph)EPDVLK ddPTM_PC-9_AZD4547_30min_R2 2 QLAEPASEPDVLK 13 0 Q8IWI9-3;Q8IWI9 Q8IWI9-3 MGA MAX gene-associated protein 1 QLAEPAS(1)EPDVLK;QLAEPAS(1)EPDVLK 150.05 0.00010121 12000000.0 72325.0 76393.0 79172.0 82439.0 79353.0 80000.0 93980.0 99144.0 80462.0 85019.0 True False 95322.84554654549 101085.54330346346 78122.12754993416 63433.96221985338 68336.2056824846 74997.58735336177 102344.03793661593 83823.5729024721 84715.05705357129 82042.5106877697 1.161871385303126 1.2321117729827418 0.9522152222674487 0.7731840686990294 0.8329365484992607 0.9141308173610277 1.2474513161366798 1.0217090164570977 1.0325751411481365 1.0 16.324084021798356 -5.264363884810207 24.79143889768203 0.9682863573990723 1.196991590477503 0.3539256413161518 0.12164222072994825 254.0774269669491 2153876.3630139 0.03589913350117639 0.08039953768894625 5.4404661835628e-06 5.264363884810207 0.22870523307843071 QLAEPAS(ph)EPDVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QLAEPASEPDVLK 13 0 Q8IWI9-3;Q8IWI9 Q8IWI9-3 MGA MAX gene-associated protein 1 QLAEPAS(1)EPDVLK;QLAEPAS(1)EPDVLK 125.22 0.00014421 6518800.0 58481.0 62099.0 61337.0 63898.0 67134.0 53392.0 69468.0 61282.0 56450.0 45868.0 True False 68380.67824759989 68263.77832200636 62799.5067018679 60318.00222011112 53979.57462545141 50592.02952875578 62887.48813523369 59673.41243364622 57275.47445709221 54183.505309111744 1.2620202007510335 1.2598627189689555 1.159015208477242 1.113217055190554 0.9962362958524568 0.9337164371358602 1.1606389763169909 1.1013206342634179 1.0570647677801774 1.0 15.725566108794228 -5.596246320588704 1.7910602224514645 1.0486668481307198 1.2656370094254117 0.6740958969848163 0.059661155771872115 0.23753404403404824 1.5079065110944698 0.0196896715228605 0.049914304977034175 2.533691178840074e-06 5.596246320588704 0.21697016129469193 QLAEPAS(ph)EPDVLK ddPTM_PC-9_Lapatinib_30min_R1 2 QLAEPASEPDVLK 13 0 Q8IWI9-3;Q8IWI9 Q8IWI9-3 MGA MAX gene-associated protein 1 QLAEPAS(1)EPDVLK;QLAEPAS(1)EPDVLK 161.82 0.00013901 11858500.0 93171.0 105360.0 95944.0 80249.0 111213.0 94739.0 92240.0 102730.0 97111.0 83309.0 True False 91842.36445453126 105116.04539329905 88055.85467455028 86150.77916281632 104671.66999317052 90687.23381739568 97015.73586621365 107503.2108343029 86173.336555835 97708.84964773509 0.9399595306427823 1.0758088522408027 0.9012065436448564 0.8817090721404611 1.071260897764513 0.9281373605803969 0.9929063356694887 1.1002402670984148 0.8819399354972605 1.0 16.57620161487212 -6.261014383016154 24.999999674734052 0.997236914693916 0.9552191040088812 0.07967513911907276 0.07568328616796961 123.38582828727553 7257995.994706288 0.02280561443332259 0.027649511581281143 5.482588073199844e-07 6.261014383016154 -0.04201781068503474 QLAPIWDK ddPTM_PC-9_Lapatinib_30min_R1 2 QLAPIWDK 8 0 P07237;H7BZ94;H0Y3Z3 P07237 P4HB Protein disulfide-isomerase 0 ; 109.71 0.017387 11486100.0 160354.0 142656.0 152801.0 135580.0 139648.0 155354.0 140753.0 127366.0 125634.0 146568.0 False True 158067.3225546776 142325.68879675842 140238.29160891692 145551.00548162134 131434.1791985315 148709.8715678618 148040.50163028162 133283.8893324428 111483.7759353294 171902.0835104164 0.919519527202819 0.8279462697037886 0.8158033267841059 0.8467087920595312 0.7645874704629001 0.8650847536635629 0.8611908512517308 0.7753477247666196 0.6485306847870406 1.0 17.391227505302403 -4.7533537759516395 3.6378562585523504 0.8160778439654249 0.934633271965686 0.10222580063016617 0.08460903048232137 0.6917266530835992 15.025564855145765 0.02055360545207203 0.23340810210172702 1.7645997934203315e-05 4.7533537759516395 0.11855542800026109 QLAT(ph)DIDY(ph)LINVMDALGLQPSRT(ph)LQHIVT(ph)LLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLATDIDYLINVMDALGLQPSRTLQHIVTLLK 32 1 P83436 P83436 COG7 Conserved oligomeric Golgi complex subunit 7 4 QLAT(1)DIDY(0.998)LINVMDALGLQPS(0.076)RT(0.935)LQHIVT(0.993)LLK 40.819 0.0119 11214000.0 13618.0 15657.0 12749.0 16540.0 19944.0 17751.0 20996.0 18490.0 17533.0 17535.0 True False 15923.258432239789 17211.323486491805 13052.984510851738 15613.317423403509 16036.11636920193 16820.10631115043 19007.106882123648 18004.65709177438 17789.386955822803 20713.956693016382 0.7687212379664887 0.8309046765698089 0.6301540890665517 0.7537583309067876 0.7741696387058894 0.8120180301825799 0.9175990451178171 0.8692041486137012 0.8588116321504339 1.0 14.338315536978973 -6.991093876383466 1.8368274873538508 0.9033334441198114 0.7456740140436096 0.619308156343842 0.058913677991290485 0.25421266343414417 1.729743718790627 0.027239683258478187 0.02100986591578528 1.0207188229517392e-07 6.991093876383466 -0.15765943007620187 QLDWRPER ddPTM_PC-9_AZD4547_30min_R2 1 QLDWRPER 8 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 0 99.139 0.0068589 3764300.0 10400.0 9432.9 13015.0 16717.0 14477.0 12311.0 9276.3 12863.0 9949.4 10427.0 False True 13706.983666561673 12481.900454586677 12842.412596150067 12863.153925075378 12467.118441209916 11541.191223840466 10101.872729425737 10875.31891233456 10475.30497189733 10061.95390373179 1.362258642576171 1.2405046349851965 1.2763338730251046 1.2783952349756518 1.2390355352936069 1.1470129295225706 1.0039673035750185 1.0808356921910671 1.041080596484569 1.0 13.296622864962318 -6.889185894605394 1.9134967374407024 1.0361306472254659 1.2844669836581954 0.9097131486482335 0.036951290786493084 0.09286958834077354 0.6956342172300541 0.015385904745079943 0.01286516433998733 1.2906667007775296e-07 6.889185894605394 0.24833633643272957 QLDWRPER ddPTM_PC-9_Lapatinib_30min_R1 1 QLDWRPER 8 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 0 76.1 0.03297 2768300.0 10327.0 11423.0 15218.0 9686.5 12864.0 12786.0 12147.0 11999.0 12906.0 10403.0 False True 10179.735086260143 11396.55074532703 13966.834783178789 10398.877523216746 12107.364811597081 12239.172585621758 12775.912224272526 12556.5173445031 11452.390373795015 12201.14468887382 0.8343262329757476 0.9340558640960551 1.1447151180753636 0.8522870426001461 0.9923138459818237 1.0031167482820376 1.047107673095856 1.0291261733789079 0.9386324534154905 1.0 13.574728884673005 -6.50446490906251 24.29987686807471 1.0069785519873502 0.9512202940605368 0.10998285163689003 0.08247577871061829 1389.3837665560613 1833507.489152561 0.026263319937158896 0.029215330484050995 3.1299333595540666e-07 6.50446490906251 -0.05575825792681344 QLEAIDQLHLEYAK ddPTM_PC-9_Lapatinib_30min_R1 1 QLEAIDQLHLEYAK 14 0 O43707;O43707-2;F5GXS2;O43707-3 O43707 ACTN4 Alpha-actinin-4 0 115.68 0.00013051 632870.0 10658.0 10441.0 12776.0 11162.0 11151.0 11883.0 11243.0 9774.4 11646.0 10764.0 False True 10506.014965562179 10416.824505993132 11725.606596786181 11982.890715340447 10495.12010370951 11374.79179062594 11825.107527578495 10228.55430720152 10334.304842183223 12624.543057871559 0.8321897210379863 0.825124874479961 0.9287945348227967 0.9491742125168615 0.831326730448725 0.9010062176890923 0.9366760819280024 0.8102118437327434 0.8185884269086203 1.0 13.62394355037841 QLEDELVSLQK ddPTM_PC-9_Lapatinib_30min_R1 2 QLEDELVSLQK 11 0 P09493-3;P09493-4;P09493-10;P09493-9;P09493;A0A0S2Z4G6;H0YKP3;A0A087WTJ7 P09493-3 TPM1 Tropomyosin alpha-1 chain 0 ; 151.1 0.0016285999999999998 10076000.0 80519.0 78711.0 77666.0 79135.0 91602.0 73226.0 84829.0 74993.0 70229.0 78989.0 False True 79370.78429462363 78528.74951548941 71280.60127942983 84954.85188662128 86214.1504564611 70094.29467814321 89221.0305485153 78477.44855540627 62319.07047584459 92642.1434037735 0.8567459838304076 0.8476568722425606 0.7694187403324525 0.9170216573719828 0.9306148075687702 0.7566134817568149 0.963071743274035 0.8471031182144446 0.6726859740737196 1.0 16.499381012002488 -5.766423280033741 24.99933760062531 0.8649473022529235 0.8269121714140258 0.04407406289577276 0.09409386249216127 530.5860058406137 2661445.2496168274 0.02600522311126186 0.0399990318399882 1.7122876328756607e-06 5.766423280033741 -0.038035130838897646 QLEEPGAGTPS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 4 QLEEPGAGTPSPVR 14 0 Q96P11-5;Q96P11;Q96P11-2;Q96P11-4;Q63ZY6-4;Q63ZY6-5;Q63ZY6 Q96P11-5 NSUN5;NSUN5P2 Probable 28S rRNA (cytosine-C(5))-methyltransferase;Putative methyltransferase NSUN5C 1 QLEEPGAGTPS(1)PVR;QLEEPGAGTPS(1)PVR;QLEEPGAGT(0.001)PS(0.999)PVR;QLEEPGAGT(0.002)PS(0.998)PVR 226.67 1.6908e-20 174295500.0 152692.0 136054.0 199139.0 245811.0 222634.0 185327.0 158554.0 223045.0 152578.0 162516.0 True False 201244.87980909983 180030.7948190202 196498.28674488887 189143.0716920921 191725.1120425729 173738.47339295613 172664.99884020252 188578.52031420855 160642.96158583922 156826.36430602055 1.2832337260360378 1.1479625611145334 1.252967175604831 1.2060668021545846 1.2225311279196223 1.1078397064280239 1.1009947186129718 1.2024669522162037 1.0243364519524996 1.0 17.258808587820155 -7.874041154578242 0.3461999188420546 0.9845241103012013 1.2502698259607952 0.6608637529620878 0.052654190094666535 0.8140103436619827 0.30875688295084136 0.07634801619107098 0.0696125564088406 1.336468864192217e-08 7.874041154578242 0.2657457156595938 QLEEPGAGTPS(ph)PVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 QLEEPGAGTPSPVR 14 0 Q96P11-5;Q96P11;Q96P11-2;Q96P11-4;Q63ZY6-4;Q63ZY6-5;Q63ZY6 Q96P11-5 NSUN5;NSUN5P2 Probable 28S rRNA (cytosine-C(5))-methyltransferase;Putative methyltransferase NSUN5C 1 QLEEPGAGT(0.001)PS(0.999)PVR;QLEEPGAGTPS(1)PVR;QLEEPGAGT(0.02)PS(0.98)PVR;QLEEPGAGTPS(1)PVR;QLEEPGAGTPS(1)PVR;QLEEPGAGT(0.001)PS(0.999)PVR 175.7 1.5490999999999998e-05 140027700.0 194625.0 184025.0 221052.0 205564.0 231824.0 213884.0 242196.0 203442.0 191454.0 163482.0 True False 227571.16848103024 202293.78582114432 226322.71802437832 194046.91552747996 186399.75136250854 202667.54651873707 219253.4415328068 198101.8630646167 194253.6525546171 193119.9924772 1.1783925918902343 1.0475030742610836 1.171927955885242 1.0047997260065624 0.965201732723323 1.049438454916387 1.1353223388235798 1.0257967625387354 1.005870236752163 1.0 17.559137999443614 -1.522878745286253 0.5663029728612207 1.033448826554275 7.65145431967097 0.34306736607204547 0.05855631289674576 189.84146181371878 1.6496332787632577 0.029466566217464754 1537.5228496609534 0.029999999999591367 1.522878745286253 6.618005493116695 QLEEPGAGTPS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 4 QLEEPGAGTPSPVR 14 0 Q96P11-5;Q96P11;Q96P11-2;Q96P11-4;Q63ZY6-4;Q63ZY6-5;Q63ZY6 Q96P11-5 NSUN5;NSUN5P2 Probable 28S rRNA (cytosine-C(5))-methyltransferase;Putative methyltransferase NSUN5C 1 QLEEPGAGT(0.002)PS(0.998)PVR;QLEEPGAGT(0.179)PS(0.821)PVR;QLEEPGAGTPS(1)PVR;QLEEPGAGTPS(1)PVR 199.05 6.7635e-08 146943800.0 342186.0 341142.0 366130.0 319710.0 335459.0 311942.0 268460.0 285455.0 363788.0 239683.0 True False 337306.36489077297 340352.10665870225 336028.20470267127 343222.53992129513 315727.96115776955 298600.96783231874 282359.54521513137 298718.2814047121 322814.3645825306 281111.88719247817 1.1999007521863287 1.2107353767849103 1.1953539498405905 1.220946376011092 1.1231398441062352 1.062213949095172 1.0044382969184042 1.0626312689515645 1.1483483242439285 1.0 18.10078493573613 -6.50531536019807 2.727781503996665 1.0561558486840326 1.2062779776773858 0.7711732410674536 0.03874615791466225 0.13449550529924423 2.0130922696505618 0.013691959175947106 0.014790087113166178 3.1238102082813505e-07 6.50531536019807 0.1501221289933532 QLEIAHEK ddPTM_PC-9_Lapatinib_30min_R1 1 QLEIAHEK 8 0 P30533 P30533 LRPAP1 Alpha-2-macroglobulin receptor-associated protein 0 66.595 0.034681000000000003 0.0 24267.0 17467.0 25715.0 20841.0 20788.0 21537.0 16062.0 18292.0 25462.0 18444.0 False True 23920.948129977227 17426.55623466927 23600.811962770556 22373.716663537936 19565.290710780493 20615.91271519912 16893.61176803042 19141.913098229084 22594.20143325342 21632.02082491482 1.1058119961878976 0.805590766378984 1.0910128163147923 1.0342869417807172 0.9044596835930392 0.9530275919231092 0.7809539342054023 0.8848878823277695 1.0444794601542913 1.0 14.40088082514992 -6.271090720491248 24.19775304942048 0.9161147484816132 1.0004793679404596 0.12510627921315398 0.10132718595482905 912.0507054692413 2286680.404215406 0.031096506939360072 0.035749270011435234 5.35684745754196e-07 6.271090720491248 0.08436461945884632 QLES(ph)GGFEAR ddPTM_PC-9_AZD4547_30min_R2 2 QLESGGFEAR 10 0 Q8IYI6 Q8IYI6 EXOC8 Exocyst complex component 8 1 QLES(1)GGFEAR;QLES(1)GGFEAR 110.15 0.0017811 9932000.0 16304.0 18241.4 38067.0 45094.0 36596.0 42795.0 24322.2 52683.0 37607.0 30722.0 True False 21488.33285573285 24137.575819980833 37562.20670746406 34698.274995354994 31515.27709294174 40119.02188483896 26486.82868165526 44542.05288490413 39594.82924378786 29646.432131049016 0.7248201996363636 0.8141814742928644 1.2670059770236153 1.1704030637472604 1.063037769726613 1.3532495818551433 0.8934238212737691 1.5024422732560379 1.3355681071085714 1.0 14.855570870271338 -5.198551555027697 4.9371408351023796 1.2050255155332528 0.7523489875255278 0.5004654237563446 0.171586360237056 0.1664227654602938 8.209264174501483 0.043251415647214055 0.12037260148105966 6.330652061818303e-06 5.198551555027697 -0.45267652800772495 QLES(ph)GGFEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLESGGFEAR 10 0 Q8IYI6 Q8IYI6 EXOC8 Exocyst complex component 8 1 QLES(1)GGFEAR 107.39 0.0021795 2592400.0 9310.6 13514.0 15758.0 10912.0 12339.0 14176.0 15245.0 10380.0 10114.0 10192.0 True False 10886.700687267714 14855.580609085406 16133.730482547791 10300.636017181327 9921.261526252638 13432.585604578251 13800.883235758018 10107.5359985191 10261.898116191853 12039.728920172389 0.9042313792486811 1.2338799907857643 1.34004100835825 0.8555538156613113 0.8240435969974133 1.1156883758464156 1.1462785688334594 0.8395152470238821 0.8523363095823688 1.0 13.555515289095098 -5.774543720596888 24.985282185672673 0.9510738981668655 1.166833755967953 0.3005982540146279 0.14782011817549884 284.9442326204155 543286.2421372873 0.04409110854486355 0.06584485350134314 1.6805687336749066e-06 5.774543720596888 0.21575985780108742 QLES(ph)GGFEAR ddPTM_PC-9_Lapatinib_30min_R1 1 QLESGGFEAR 10 0 Q8IYI6 Q8IYI6 EXOC8 Exocyst complex component 8 1 QLES(1)GGFEAR 74.392 0.025939999999999998 4993600.0 7903.4 6746.0 8818.8 9782.0 9988.1 12074.0 6779.0 8879.6 12967.0 6705.1 True False 7790.696066693944 6730.380051473002 8093.7523055524425 10501.400911795407 9400.619595360145 11557.623165868692 7129.983450098251 9292.178632573527 11506.519911436531 7864.067601015848 0.9906700275170033 0.8558395467764798 1.0292068578488471 1.3353650355750857 1.1953889605610477 1.4696749509599494 0.9066533773409106 1.1815995365265173 1.4631766275699571 1.0 12.94106000807394 -5.577649137255547 5.326393696375278 1.2244790639790613 0.9266036251101192 0.3421388991593345 0.17117400789299156 0.2019027249796079 12.059729954098534 0.046058783513172816 0.08247701608909339 2.644544399001298e-06 5.577649137255547 -0.2978754388689421 QLFDQVVK ddPTM_PC-9_Lapatinib_30min_R1 2 QLFDQVVK 8 0 P15311;E7EQR4;E9PQ82;A0A2R8Y7M3;A0A2R8Y5S7;P35241;P35241-5;E9PNV3;P26038;V9GZ54 P15311;A0A2R8Y7M3;P26038 EZR;RDX;MSN Ezrin;Radixin;Moesin 0 ; 138.1 0.0045271999999999995 5876100.0 121061.0 101933.0 105339.0 102295.0 103682.0 91096.0 96932.0 82040.0 105144.0 90642.0 False True 119334.64794013146 101696.98040124465 96678.43404029873 109818.11554611637 97583.6286066548 87200.03643514783 101950.66466808146 85851.87790174464 93301.57550459488 106309.34892712718 1.1225226110822375 0.9566137073321349 0.9094066986203608 1.033005249814806 0.917921420754315 0.8202480526423092 0.9589999910352803 0.807566585330085 0.8776422435674133 1.0 16.697908948612785 -1.5228787453790462 0.6165959915735502 0.894928078933373 15.640081283295645 0.44882119561686873 0.06779627485839794 170.11129353662156 1.2423607983743912 0.02992628269194701 3395.440302220684 0.029999999993181446 1.5228787453790462 14.745153204362271 QLFHPEQLITGK ddPTM_PC-9_AZD4547_30min_R2 2 QLFHPEQLITGK 12 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;F8VRZ4;F8VS66;F8VWV9;F8VX09;Q9NY65-2;Q9NY65;C9J2C0;C9K0S6;P68363;P68363-2;P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8;C9JDL2;Q71U36-2;Q71U36 Q9BQE3;P68363;P68366-2;Q71U36-2 TUBA1C;TUBA1B;TUBA1A;TUBA3E;TUBA8;TUBA4A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-8 chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain;Tubulin alpha-1A chain 0 ; 141.73 6.6559e-05 21596000.0 209814.0 205601.0 177463.0 174646.0 171449.0 194767.0 193968.0 235484.0 180477.0 177179.0 False True 276530.48759768985 272057.5025033104 175109.72466773563 134384.06295380244 147646.2657751605 182588.18870065306 211230.77623419397 199095.35868399267 190016.6457689019 170976.01713909008 1.6173641907492238 1.5912027140156733 1.0241771190943274 0.785981947658075 0.8635495682125366 1.0679169614304234 1.2354409686731467 1.1644636599648204 1.1113643243562175 1.0 17.383434446442365 -5.2574472605205465 8.484943802249866 1.0310759084483656 1.6056276374346468 0.7699198100726342 0.12522652804642223 0.061037273237895845 54.0920408720491 0.038170396257794476 0.0910063932743277 5.527805319550857e-06 5.2574472605205465 0.5745517289862812 QLFHPEQLITGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLFHPEQLITGK 12 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;F8VRZ4;F8VS66;F8VWV9;F8VX09;Q9NY65-2;Q9NY65;C9J2C0;C9K0S6;P68363;P68363-2;P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8;C9JDL2;Q71U36-2;Q71U36 Q9BQE3;P68363;P68366-2;Q71U36-2 TUBA1C;TUBA1B;TUBA1A;TUBA3E;TUBA8;TUBA4A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-8 chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain;Tubulin alpha-1A chain 0 113.52 0.00069134 13789000.0 106910.0 129810.0 135150.0 132990.0 136780.0 104000.0 138980.0 93211.0 100570.0 90196.0 False True 125007.75143124947 142696.67891559697 138372.48855922953 125539.00145939755 109978.94088344577 98546.05691846352 125814.80827193514 90764.31001521826 102040.64599025264 106547.82080885688 1.1732548867002084 1.3392735565337361 1.2986890535045763 1.178240911042284 1.032202630223139 0.9248997883800154 1.180829484045878 0.8518645367514959 0.9576981041527827 1.0 16.701141560843155 -6.168607543308918 2.375722327138841 0.9850892757344238 1.2762224071774135 0.6815419549471367 0.08768438876682401 0.17184454330225973 1.900335927366588 0.02837093397304678 0.03858656619362643 6.782541452417446e-07 6.168607543308918 0.2911331314429897 QLFHPEQLITGK ddPTM_PC-9_Lapatinib_30min_R1 2 QLFHPEQLITGK 12 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;F8VRZ4;F8VS66;F8VWV9;F8VX09;Q9NY65-2;Q9NY65;C9J2C0;C9K0S6;P68363;P68363-2;P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8;C9JDL2;Q71U36-2;Q71U36 Q9BQE3;P68363;P68366-2;Q71U36-2 TUBA1C;TUBA1B;TUBA1A;TUBA3E;TUBA8;TUBA4A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-8 chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain;Tubulin alpha-1A chain 0 ; 139.89 6.1911e-05 51978000.0 179124.0 196552.0 198414.0 206858.0 208247.0 199870.0 218509.0 203532.0 196442.0 199524.0 False True 176569.65891268183 196096.89592011864 182101.16682018864 222071.02737805952 195998.3208893547 191322.0260197262 229822.32684725156 212988.8397500958 174316.63333403366 234011.45755098166 0.7545342470003393 0.8379798919777124 0.7781720122849802 0.9489750190102516 0.8375586517880416 0.8175754641331818 0.9820986085571581 0.9101641517005384 0.7449064039783483 1.0 17.83621964248188 -1.5229038811668576 0.02939678443254275 1.4622536245627369 7.423030552664622e-08 0.28245950691751254 0.07518522398971239 1990.53664472575 4.505309262232444 72.16573357188567 171.59590720846433 0.02999826372471813 1.5229038811668576 -1.4622535503324314 QLFHPEQLITGKEDAANNYAR ddPTM_PC-9_AZD4547_30min_R2 2 QLFHPEQLITGKEDAANNYAR 21 1 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;F8VQQ4;F8VRZ4;F8VS66;F8VWV9;F8VX09;Q9NY65-2;Q9NY65;C9J2C0;C9K0S6;P68363;P68363-2;P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8;C9JDL2;Q71U36-2;Q71U36 Q9BQE3;P68363;P68366-2;Q71U36-2 TUBA1C;TUBA1B;TUBA1A;TUBA8;TUBA4A Tubulin alpha-1C chain;Tubulin alpha-8 chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain;Tubulin alpha-1A chain 0 ; 100.97 8.2796e-05 16533600.0 68416.0 42777.0 85223.0 160071.0 125380.0 76020.0 61805.0 94254.0 70975.0 94661.0 False True 90170.86485879659 56603.82870017217 84092.88733628095 123169.10402229703 107973.15121633606 71266.45738253201 67305.52526785008 79689.21004145095 74726.5936016657 91346.94720256588 0.9871251051098481 0.6196575849946105 0.920587823803255 1.348365849043254 1.1820115999815608 0.7801733890952645 0.7368119825460299 0.8723795647460075 0.8180524460872918 1.0 16.47906889461663 -6.794985900728366 24.9996169186421 0.8269651598816086 1.003436642807681 0.169427286781213 0.18646224560403818 385.4648508576929 287254.3645001101 0.07376973498991513 0.06506239732809713 1.603297440532099e-07 6.794985900728366 0.1764714829260725 QLFHPEQLITGKEDAANNYAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLFHPEQLITGKEDAANNYAR 21 1 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;F8VQQ4;F8VRZ4;F8VS66;F8VWV9;F8VX09;Q9NY65-2;Q9NY65;C9J2C0;C9K0S6;P68363;P68363-2;P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8;C9JDL2;Q71U36-2;Q71U36 Q9BQE3;P68363;P68366-2;Q71U36-2 TUBA1C;TUBA1B;TUBA1A;TUBA8;TUBA4A Tubulin alpha-1C chain;Tubulin alpha-8 chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain;Tubulin alpha-1A chain 0 82.865 0.00026713 5937700.0 50918.0 23296.0 47134.0 72814.0 68118.0 80546.0 69104.0 82638.0 78034.0 56326.0 False True 59537.41172365881 25608.67292209957 48257.853316690416 68734.46764617293 54770.76688915445 76322.02596687082 62557.96885036543 80468.8400621985 79175.09962417604 66537.45792362922 0.8947954067015159 0.38487603406028603 0.7252734748610342 1.0330191412642395 0.8231568893422346 1.147053529674551 0.94019174766443 1.209376531254914 1.1899327400672886 1.0 16.021879128381734 -5.9898807025817495 1.0445505680505156 1.0992530254394228 0.6130709478243587 0.5281288481363575 0.16253465626217214 0.4092665608721354 0.9060295233557221 0.06528044470545569 0.13833744029413927 1.023574121757234e-06 5.9898807025817495 -0.48618207761506416 QLHDDYFYHDEL ddPTM_PC-9_AZD4547_30min_R2 1 QLHDDYFYHDEL 12 0 A8MXP8;Q14257;Q14257-2 A8MXP8 RCN2 Reticulocalbin-2 0 134.98 4.9525e-05 2971900.0 10538.0 11574.0 18325.0 20337.0 17486.0 17583.0 13114.0 16275.0 12244.0 14806.0 False True 13888.86479598337 15315.06915809413 18081.9985266577 15648.618853517844 15058.37073033062 16483.532230427012 14281.120594815733 13760.072712294565 12891.192843378587 14287.646446595665 0.9720890594470644 1.0719098639050708 1.265568727098935 1.0952551851005845 1.0539434039480027 1.1536912179370566 0.9995432521511276 0.9630748327743786 0.9022614670347044 1.0 13.80248066550938 -7.451197046005001 3.866440602449345 0.952793002882587 1.1053765293595537 0.4532054728551438 0.07402414246099469 0.21970738457129216 6.313086034972047 0.03556084361022958 0.022262886526038694 3.538367635422279e-08 7.451197046005001 0.1525835264769667 QLHDDYFYHDEL ddPTM_PC-9_Lapatinib_30min_R1 1 QLHDDYFYHDEL 12 0 A8MXP8;Q14257;Q14257-2 A8MXP8 RCN2 Reticulocalbin-2 0 134.98 4.9525e-05 3805300.0 20564.0 16383.0 20987.0 14308.0 18933.0 20149.0 13760.0 12511.0 14238.0 14261.0 False True 20270.75358902427 16345.066170068514 19261.529872162766 15360.2580500888 17819.398163710168 19287.27423961309 14472.42547180291 13092.306733650985 12634.366507213179 16725.99484841197 1.2119311151736276 0.9772253500138066 1.151592479056128 0.9183464534874684 1.065371496596031 1.1531316620873104 0.8652654507529624 0.7827520486707562 0.7553730956943786 1.0 14.029804403282279 -7.3669893637624195 5.520065689672744 0.8271786551612302 1.0697359894647425 0.5461506244640948 0.10140666528142774 0.1681755592170068 7.313015660764358 0.041598054366032464 0.027679286262671236 4.2954694660251e-08 7.3669893637624195 0.24255733430351223 QLHS(ph)SPGNSSR ddPTM_PC-9_AZD4547_30min_R2 1 QLHSSPGNSSR 11 0 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 QLHS(0.789)S(0.208)PGNS(0.003)SR 141.73 0.00013395 8073900.0 13644.0 10317.0 18820.0 30964.0 24005.0 25426.0 18831.0 24022.0 20795.0 26816.0 True False 17982.508187169962 13651.768490068875 18570.43450323046 23825.728189031168 20672.32010646154 23836.10820058222 20506.922519519223 20309.951870644552 21894.181246166103 25877.180002155157 0.6949176141168514 0.5275601317041463 0.7176374899306585 0.9207235172861519 0.7988629404262699 0.9211246433574699 0.792471301656955 0.7848595507297571 0.8460806488320082 1.0 14.659392785961117 -5.549044426579804 4.975583093404688 0.8528354438643839 0.6120851545373013 0.6552905113821417 0.07512001693370605 0.10191306762018934 6.577318801534902 0.019390283933132853 0.03596089261907031 2.8245910158291205e-06 5.549044426579804 -0.24075028932708264 QLHS(ph)SPGNSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QLHSSPGNSSR 11 0 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 QLHS(0.5)S(0.5)PGNSSR;QLHS(0.499)S(0.499)PGNS(0.001)SR 124.38 0.00051456 10370400.0 23750.0 31430.0 34207.0 28501.0 52355.0 43885.0 29531.0 36518.0 42416.0 41027.0 True False 27770.40591611802 34550.162686366304 35022.62461076993 26904.18137148872 42096.4135835122 41583.59334487281 26733.609894074776 35559.441194019295 43036.25375681173 48464.870330446705 0.5730007266453375 0.7128908516786255 0.7226393957515233 0.5551274807514943 0.8685964348297514 0.8580151573984317 0.5516079938272347 0.7337158018078935 0.8879886289466745 1.0 15.564651770895098 -14.52287874499858 0.10984641188592138 1.949629998305464 0.5492925349118768 0.44915600907696296 0.10963182116604447 171.7590948811584 1.2501410634227759 36.301925743225894 1.4419127676387502 3.0000000019463086e-15 14.52287874499858 -1.400337463393587 QLHS(ph)SPGNSSR ddPTM_PC-9_Lapatinib_30min_R1 2 QLHSSPGNSSR 11 0 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 QLHS(0.473)S(0.473)PGNS(0.039)S(0.015)R;QLHS(0.463)S(0.463)PGNS(0.065)S(0.01)R 86.262 0.011014 12644400.0 27455.0 26168.9 32274.0 26691.1 34324.0 26957.0 30533.7 31847.0 35218.0 21909.0 True False 27063.486665369634 26108.307519862425 29620.556301242745 28654.052532899437 32305.129803580418 25804.11194983622 32114.58558345848 33326.727883189444 31251.377978018958 25695.941458092537 1.0532202803118704 1.016047906337365 1.1527328683228382 1.115119777947474 1.2572074798764152 1.0042096333352915 1.249792136856869 1.296964656365751 1.2161989872597885 1.0 14.649252890693848 -5.4295722568103315 1.436625087364327 1.1805859499492644 1.0231937713423884 0.1935077936851386 0.09747157086327171 0.7518414818658704 2.744513117505305 0.0303241995316106 0.11929178432987918 3.719013400160686e-06 5.4295722568103315 -0.15739217860687593 QLHSSPGNS(ph)SR ddPTM_PC-9_AZD4547_30min_R2 1 QLHSSPGNSSR 11 0 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 QLHS(0.081)S(0.081)PGNS(0.535)S(0.303)R 81.565 0.014915000000000001 7331700.0 6933.5 4787.7 9878.5 9594.8 8385.7 8547.2 9096.7 10071.0 13000.0 14473.0 True False 9138.2087742409 6335.230396423642 9747.504635502766 7382.867098182287 7221.490302718378 8012.742232833172 9906.288677357052 8514.758358557214 13687.153459973999 13966.304675238353 0.6543039828167679 0.4536082051579276 0.6979301155290322 0.5286199370454654 0.5170652130711257 0.5737195642766847 0.7092991960085525 0.6096643712530135 0.980012521439599 1.0 13.76966273015103 -8.26199558341959 3.9259322390396543 1.0070663460615343 0.5877035809962375 0.8125437389869726 0.07630865751610895 0.085334572088025 2.9411864673965713 0.066287934258462 0.019537758807084693 5.470215258296537e-09 8.26199558341959 -0.4193627650652968 QLHVLVPQS(ph)PPTDLPGLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLHVLVPQSPPTDLPGLTR 19 0 O95402 O95402 MED26 Mediator of RNA polymerase II transcription subunit 26 1 QLHVLVPQS(1)PPTDLPGLTR 102.16 0.00020222 4170900.0 19865.0 21397.0 22391.0 25253.0 29499.0 27723.0 28928.0 27201.0 25999.0 21447.0 True False 23227.752148365656 23521.152752153343 22924.886358340376 23838.15628133064 23718.882710343354 26269.157076447733 26187.730419416708 26487.002571841815 26379.18618972434 25335.171325641404 0.916818435913127 0.928399198482936 0.9048640746762344 0.9409115878843237 0.9362037621722248 1.036865183929546 1.0336512069650952 1.045463724377291 1.0412081233106287 1.0 14.62885396447138 -6.730063447249061 4.777990509608956 1.0349475145779756 0.9240001960200854 0.9288945943207627 0.014669865753450933 0.045305820101407754 2.449253947373001 0.004945105913581338 0.00476432047033664 1.8618151192146458e-07 6.730063447249061 -0.1109473185578902 QLICDPSYVK ddPTM_PC-9_Lapatinib_30min_R1 2 QLICDPSYVK 10 0 P50395;P50395-2;Q5SX91 P50395 GDI2 Rab GDP dissociation inhibitor beta 0 ; 166.19 1.0951e-18 3181500.0 44412.0 32458.0 36512.0 36488.0 38169.0 40147.0 35329.0 29441.0 33203.0 37819.0 False True 43778.67673583666 32382.845495213587 33510.12430039581 39171.449240399816 35923.974463141254 38430.00639722797 37158.162753875404 30808.936339654632 29463.328496909646 44355.96375935011 0.9869851317706572 0.7300674531818143 0.7554818216148436 0.8831157283138186 0.8099017903893156 0.8663999863857548 0.8377264206336306 0.6945838558892815 0.6642472849143958 1.0 15.436840470718575 -7.721099212788909 24.910691164124234 0.7595615538353959 0.832846278015773 0.028285871959656594 0.1075305692730691 351.6518308258465 217150.23398764228 0.048475930348639056 0.02798711344608152 1.9006440360085173e-08 7.721099212788909 0.07328472418037713 QLILPGNS(ph)GNLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLILPGNSGNLK 12 0 Q9P270;D6RIF6 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 QLILPGNS(1)GNLK 125.03 0.00030491 4334600.0 34576.0 32599.0 34321.0 33626.0 33555.0 26607.0 31979.0 28804.0 25677.0 19451.0 True False 40429.03389287143 35835.21328071446 35139.34280311734 31742.044236962913 26980.13862658297 25211.682081053434 28949.717612089564 28047.925520360714 26052.4775488885 22977.31232596872 1.7595197088033208 1.5595911642030418 1.5293060521879758 1.3814515721705356 1.1742077682466934 1.0972424330307533 1.259926191601221 1.2206791256722067 1.1338348532366973 1.0 14.48792243424521 -5.698339706344023 0.9858128640465046 1.1478063868044883 1.7338361219841505 0.8872502450376704 0.07648649386679965 0.22554746938492484 0.3991920138705653 0.03061890932444225 0.10312579862425741 2.002904736854906e-06 5.698339706344023 0.5860297351796622 QLILPGNS(ph)GNLK ddPTM_PC-9_Lapatinib_30min_R1 1 QLILPGNSGNLK 12 0 Q9P270;D6RIF6 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 QLILPGNS(1)GNLK 95.264 0.014816999999999999 0.0 41222.0 41245.0 41070.0 37381.0 33257.0 30826.0 30215.0 25603.0 30115.0 26180.0 True False 40634.16672081104 41149.49973658525 37693.38313478463 40130.12343936045 31300.888645777693 29507.643838915712 31779.38485686954 26792.608848346776 26723.13157499121 30705.178117342755 1.3233652827390778 1.3401485436537293 1.2275904406330354 1.3069497035972035 1.0194009794099996 0.9609989470228587 1.0349845467569543 0.8725762392895516 0.8703135175723855 1.0 14.906194351570596 -6.34532464850458 2.7786981191381632 0.9456602102248816 1.302519738993436 0.9004445395386903 0.05564346981036178 0.08490485165368174 1.2806636037279182 0.01950882717870318 0.023148668087929484 4.5151829435374707e-07 6.34532464850458 0.3568595287685544 QLLDS(ph)DEEQEEDEGR ddPTM_PC-9_Lapatinib_30min_R1 2 QLLDSDEEQEEDEGR 15 0 Q9UNS1-2;Q9UNS1 Q9UNS1-2 TIMELESS Protein timeless homolog 1 QLLDS(1)DEEQEEDEGR;QLLDS(1)DEEQEEDEGR 153.41 0.00015618 14922100.0 28744.0 40073.0 39900.0 28916.0 40888.0 31555.0 30178.0 42770.0 40311.0 32070.0 True False 28334.10528899599 39980.213430577765 36619.57601845402 31042.579100948267 38483.04822890095 30205.46620829771 31740.469177911953 44757.25033956142 35770.750686351355 37613.2567694111 0.7533010359272756 1.0629287879982674 0.9735816348728094 0.8253095256083642 1.0231245984579886 0.803053731652991 0.8438638901304825 1.1899328636694964 0.9510144496565329 1.0 15.198953608067002 -7.741799021983277 24.999997687709186 1.0528553547664188 0.9055187629226716 0.2793761536729794 0.10913356241352769 298.0292031939923 379358.95764365915 0.04994988383726826 0.02878597118893977 1.8121785186201568e-08 7.741799021983277 -0.14733659184374714 QLLEEELAR ddPTM_PC-9_Lapatinib_30min_R1 1 QLLEEELAR 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 111.06 0.010415 3682100.0 16283.0 20702.0 24972.0 16683.0 19779.0 28143.0 17640.0 19864.0 23397.0 15328.0 False True 16050.801434063509 20654.065790927096 22918.89855470762 17909.92347285655 18615.638107010152 26939.389494537256 18553.312886817115 20786.953957097216 20761.783478667418 17977.424376723826 0.8928309805516522 1.1488890376125758 1.2748710868939457 0.9962452405610076 1.0355008435531317 1.4985121856174728 1.0320339831794212 1.156280984500261 1.154880868560272 1.0 14.133898720474173 -4.761868112749575 8.135478419698353 1.1528491495428992 0.8898810910497058 0.21052017540677792 0.14513570411808416 0.1403746589056504 87.6775161494003 0.035380689104351506 0.20453153719881362 1.7303417524158998e-05 4.761868112749575 -0.2629680584931934 QLLGLQPIST(ph)VSPLHR ddPTM_PC-9_Lapatinib_30min_R1 1 QLLGLQPISTVSPLHR 16 0 Q9UKK3 Q9UKK3 PARP4 Poly [ADP-ribose] polymerase 4 1 QLLGLQPIS(0.265)T(0.683)VS(0.052)PLHR 89.604 0.0077897999999999995 9592700.0 41348.0 32130.0 40463.0 32366.0 36369.0 32420.0 32142.0 28704.0 40530.0 25667.0 True False 40758.36993770548 32055.60495906132 37136.28833169686 34746.3036098109 34229.846924205114 31033.47217471121 33806.15548798615 30037.69262910383 35965.08460017912 30103.50675087228 1.353940930370993 1.0648462062690578 1.2336200110846156 1.1542277747692664 1.1370717440822162 1.0308922622050332 1.1229972563580681 0.9978137390333589 1.194714120777208 1.0 14.877643935551394 -1.5228787452803376 0.32095313871068604 1.0587011807650937 3.186669806537153 0.42784690008048565 0.08083005035147915 57.54325388804081 0.8211268568034675 0.0720376808808558 71.94706206321638 0.029999999999999995 1.5228787452803376 2.127968625772059 QLLGLQPISTVS(ph)PLHR ddPTM_PC-9_AZD4547_30min_R2 2 QLLGLQPISTVSPLHR 16 0 Q9UKK3 Q9UKK3 PARP4 Poly [ADP-ribose] polymerase 4 1 QLLGLQPIS(0.019)T(0.067)VS(0.914)PLHR;QLLGLQPIS(0.008)T(0.012)VS(0.98)PLHR 115.74 9.698399999999999e-05 30344000.0 87120.0 87450.0 116319.0 136862.0 137497.0 109804.0 86585.0 130405.0 100356.0 113300.0 True False 114822.34779142817 115716.50232204361 114776.53405851564 105310.58039682166 118407.91492098091 102937.93852185694 94290.89726262912 110253.9036587877 105660.61327916547 109333.40148583589 1.050203745890988 1.058381983451184 1.0497847181072557 0.9632059276090905 1.0829985467553631 0.9415049483774867 0.8624162056720104 1.0084192219435437 0.9664074458787764 1.0 16.738374687857004 -6.77661912842892 24.985820884811666 0.9504424082696332 1.0380609669926235 0.44685613320473494 0.04713931120966056 225.9735048668637 371949.257824021 0.016843136821777092 0.014909094102752162 1.672556785549079e-07 6.77661912842892 0.08761855872299029 QLLGLQPISTVS(ph)PLHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QLLGLQPISTVSPLHR 16 0 Q9UKK3 Q9UKK3 PARP4 Poly [ADP-ribose] polymerase 4 1 QLLGLQPIS(0.017)T(0.062)VS(0.921)PLHR;QLLGLQPIST(0.001)VS(0.999)PLHR 150.61 1.7521e-05 26390000.0 100551.0 89893.0 111494.0 108291.0 124753.0 105034.0 111597.0 73310.0 91481.0 87254.0 True False 117572.29832722466 98816.98295785973 114152.4398033494 102223.80635415883 100308.54519690362 99525.83213821058 101025.72426768675 71385.69017836575 92818.73655995134 103072.45949771628 1.1406761699504187 0.9587137382711738 1.107497001232212 0.9917664413200866 0.9731847448456986 0.9655909311101257 0.9801427535541162 0.692577731493323 0.9005192755879458 1.0 16.653299376941327 -6.890612118997454 1.0331275662396842 0.8611866156054726 1.0512173733960688 0.3662112326059186 0.09127470041991818 0.5151935200117524 1.1579164741358685 0.053402195028414895 0.04261030499398779 1.2864350995273442e-07 6.890612118997454 0.1900307577905962 QLLGLQPISTVS(ph)PLHR ddPTM_PC-9_Lapatinib_30min_R1 1 QLLGLQPISTVSPLHR 16 0 Q9UKK3 Q9UKK3 PARP4 Poly [ADP-ribose] polymerase 4 1 QLLGLQPIS(0.039)T(0.085)VS(0.876)PLHR 81.89 0.0038717 11194000.0 56840.0 43919.0 48084.0 45724.0 39031.0 40537.0 37853.0 33093.0 42522.0 35358.0 True False 56029.45117682058 43817.30825387533 44130.71912960762 49086.69549079259 36735.27331789848 38803.327006362386 39812.843123848514 34630.62159193606 37732.7245834892 41469.58318842648 1.3510975242321108 1.056613182119083 1.064170790651299 1.183679499930251 0.8858365696849041 0.9357057395549565 0.9600492713647449 0.8350848725578929 0.9098891689371941 1.0 15.339765926310756 -1.5228787588852006 0.39138215048330793 0.9035625396935305 7.139124986835115 0.6783303676874557 0.0831799778868284 41.71988948989922 0.5607187451513379 0.062441743216730225 199.20052727030117 0.029999999060209368 1.5228787588852006 6.235562447141584 QLLHLCLQDGGS(ph)PPGPGDLAEER ddPTM_PC-9_AZD4547_30min_R2 4 QLLHLCLQDGGSPPGPGDLAEER 23 0 Q96FS4;F6RY50 Q96FS4 SIPA1 Signal-induced proliferation-associated protein 1 1 QLLHLCLQDGGS(1)PPGPGDLAEER;QLLHLCLQDGGS(1)PPGPGDLAEER;QLLHLCLQDGGS(1)PPGPGDLAEER;QLLHLCLQDGGS(1)PPGPGDLAEER 153.48 1.5742e-08 22193000.0 66033.6 59030.9 79186.5 100886.6 89526.0 85543.5 79178.6 93384.7 70285.7 79299.2 True False 87030.91121579491 78111.48401283397 78136.4352704601 77628.75305243231 77096.86023124665 80194.45142202883 86225.3420107272 78954.24038192397 74000.85861089951 76522.95914479812 1.1373176388946675 1.0207588008329633 1.021084863205681 1.014450485448972 1.0074997241724877 1.0479789636765542 1.1267904818940686 1.0317719187064542 0.967041257132696 1.0 16.22360504336652 QLLHLCLQDGGS(ph)PPGPGDLAEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QLLHLCLQDGGSPPGPGDLAEER 23 0 Q96FS4;F6RY50 Q96FS4 SIPA1 Signal-induced proliferation-associated protein 1 1 QLLHLCLQDGGS(1)PPGPGDLAEER;QLLHLCLQDGGS(1)PPGPGDLAEER;QLLHLCLQDGGS(1)PPGPGDLAEER;QLLHLCLQDGGS(1)PPGPGDLAEER 148.3 5.202600000000001e-07 18118900.0 61492.6 69875.0 64857.0 76481.0 87540.0 70440.0 78465.0 67475.0 70409.0 58904.4 True False 71902.08264578851 76811.72821221274 66403.43685154222 72196.01752474764 70387.1654111482 66746.00239746696 71032.22716259447 65703.85274567202 71438.59842425857 69583.30143302627 1.0333238171372778 1.1038816300796508 0.954301326381522 1.0375480329032118 1.011552541508765 0.9592244263044892 1.020822894282514 0.9442474184544376 1.0266629629957702 1.0 16.08645350990222 -5.259299334766664 24.999978550174497 0.9941597900961674 1.0686027235415083 0.4286369325981826 0.03431641035529513 161.15806468742312 1882612.6194736946 0.008292749574020989 0.01979047616761454 5.504281864338088e-06 5.259299334766664 0.07444293344534092 QLLHLCLQDGGS(ph)PPGPGDLAEER ddPTM_PC-9_Lapatinib_30min_R1 4 QLLHLCLQDGGSPPGPGDLAEER 23 0 Q96FS4;F6RY50 Q96FS4 SIPA1 Signal-induced proliferation-associated protein 1 1 QLLHLCLQDGGS(1)PPGPGDLAEER;QLLHLCLQDGGS(1)PPGPGDLAEER;QLLHLCLQDGGS(1)PPGPGDLAEER;QLLHLCLQDGGS(1)PPGPGDLAEER 131.97 2.0285000000000003e-08 14352500.0 62044.0 61234.5 67804.0 60731.0 68197.0 66364.0 66156.5 61942.0 66156.0 51484.6 True False 61159.24118252386 61092.71527748648 62229.41685100894 65197.360332677046 64185.78654046062 63525.76642203987 69581.75986375943 64820.05145038847 58704.81462643603 60383.64451108272 1.012844482603212 1.0117427620036021 1.030567421938029 1.0797188685871855 1.0629664217879407 1.0520359765694576 1.1523279263309207 1.073470340772351 0.9721972746388543 1.0 15.881870214231213 -5.58000496149747 4.654446264531299 1.0631799034929537 1.0139266327218295 0.12022864551606083 0.045547312062614996 0.3559619824074914 15.857273879357043 0.012735755943574182 0.023222384689399373 2.6302379431750156e-06 5.58000496149747 -0.04925327077112418 QLLLQQQQQQQVS(ph)GLKSPK ddPTM_PC-9_AZD4547_30min_R2 1 QLLLQQQQQQQVSGLKSPK 19 1 A0A3B3IRY1;A0A087WVT2;A0A3B3IU08;A0A3B3IU15;G5E965;C9J0F0;A0A3B3IST6;A0A3B3IUB6;A0A3B3IRS5;A0A3B3IST0;Q9H334-6;Q9H334-3;Q9H334-7;Q9H334;Q9H334-4;Q9H334-8 A0A3B3IRY1 FOXP1 Forkhead box protein P1 1 QLLLQQQQQQQVS(0.852)GLKS(0.148)PK 82.70700000000001 0.00083381 11455000.0 11668.0 12415.0 11986.0 12894.0 10969.0 12320.0 9988.3 11238.0 12261.0 11521.0 True False 15378.181290523233 16427.905961442782 11827.05780848672 9921.48751031417 9446.14368872221 11549.628452417717 10877.23935009898 9501.425323549398 12909.091428672395 11117.653296719483 1.3832218796624027 1.4776415060802632 1.0638088356269 0.8924084287861117 0.8496526592990186 1.0388548863837748 0.9783754772518907 0.8546250786893138 1.1611345563799436 1.0 13.440564677100776 -5.357140707436536 3.968242058669156 0.9614371602700051 1.4318808417154552 0.7988774525786337 0.09117967268236235 0.0863708690347514 2.423399216018503 0.023810791171495715 0.05446877861867602 4.3939923104492155e-06 5.357140707436536 0.47044368144545 QLLLQQQQQQQVSGLKS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLLLQQQQQQQVSGLKSPK 19 1 A0A3B3IRY1;A0A087WVT2;A0A3B3IU08;A0A3B3IU15;G5E965;C9J0F0;A0A3B3IST6;A0A3B3IUB6;A0A3B3IRS5;A0A3B3IST0;Q9H334-6;Q9H334-3;Q9H334-7;Q9H334;Q9H334-4;Q9H334-8 A0A3B3IRY1 FOXP1 Forkhead box protein P1 1 QLLLQQQQQQQVS(0.185)GLKS(0.815)PK 71.634 0.0029131 9449200.0 26648.0 28984.0 22486.0 33988.0 34607.0 23860.0 28059.0 27801.0 21933.0 24643.0 True False 31158.98007800894 31861.33997141716 23022.151518629867 32083.76255058272 27826.006778428142 22608.73959687058 25401.048390431864 27071.25320759438 22253.728631840622 29110.58082611933 1.0703661415800982 1.0944934476480705 0.7908516719794664 1.1021340571053022 0.9558726067554582 0.7766502404027952 0.8725709920442705 0.9299454850899033 0.7644549851054009 1.0 14.829256004534082 -6.534402072079698 21.539803842147517 0.8647722602803014 1.007305484556157 0.3051680138684718 0.10384943701221257 52.89252958683924 98864.89121239961 0.03339716282463173 0.033449338160554835 2.9214464352146517e-07 6.534402072079698 0.14253322427585569 QLLLQQQQQQQVSGLKS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 QLLLQQQQQQQVSGLKSPK 19 1 A0A3B3IRY1;A0A087WVT2;A0A3B3IU08;A0A3B3IU15;G5E965;C9J0F0;A0A3B3IST6;A0A3B3IUB6;A0A3B3IRS5;A0A3B3IST0;Q9H334-6;Q9H334-3;Q9H334-7;Q9H334;Q9H334-4;Q9H334-8 A0A3B3IRY1 FOXP1 Forkhead box protein P1 1 QLLLQQQQQQQVS(0.178)GLKS(0.822)PK;QLLLQQQQQQQVS(0.18)GLKS(0.82)PK 90.978 0.00045535 21791600.0 114054.0 84846.0 78732.0 80487.0 83242.0 79282.0 89870.0 89540.0 80220.0 76456.0 True False 112427.569045058 84649.54429992285 72258.95887430878 86406.28247676128 78345.86922006881 75891.29367536875 94523.0288627128 93700.35528184094 71184.77884595038 89671.31772878357 1.2537740259946009 0.9439979967279015 0.8058201965188072 0.9635888561167619 0.8737004340343333 0.8463274054353327 1.0541054961253444 1.0449311737030946 0.793841114962235 1.0 16.452358977987103 -4.7646083924996 5.529940938321416 0.9228907998204884 1.26887825604337 0.5545280295733898 0.0885331486887331 0.11124868147577653 10.934485264434974 0.02226682283321042 0.14708315424533489 1.719458140238316e-05 4.7646083924996 0.34598745622288163 QLLT(ph)LSSELSQAR ddPTM_PC-9_AZD4547_30min_R2 3 QLLTLSSELSQAR 13 0 P15311;E7EQR4 P15311 EZR Ezrin 1 QLLT(0.977)LS(0.011)S(0.011)ELSQAR;QLLT(0.408)LS(0.226)S(0.183)ELS(0.183)QAR;QLLT(0.825)LS(0.124)S(0.051)ELSQAR 163.33 0.00043793 6381200.0 17965.0 22790.1 30794.8 39473.6 33815.8 34378.4 30894.9 38248.1 33793.5 32288.3 True False 23677.496304786593 30156.554140304204 30386.440831035106 30373.571381040587 29121.05987319651 32228.713213360184 33644.48624864823 32337.734998901007 35579.75541920242 31157.89644479363 0.7599196032613753 0.9678623264486539 0.975240446185916 0.9748274064283277 0.9346285595625482 1.034367428188352 1.0798060873031146 1.0378664380054619 1.141917763358754 1.0 14.927310215930238 -3.300064989200288 0.43197273385515184 1.0602519360861997 1.8556629034578551e-13 0.6851649574332603 0.053947748526615144 11.055670807371074 0.5866519096536673 0.03784277569811072 7.8930105995257644 0.0005011122399952642 3.300064989200288 -1.060251936086014 QLLT(ph)LSSELSQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLLTLSSELSQAR 13 0 P15311;E7EQR4 P15311 EZR Ezrin 1 QLLT(0.742)LS(0.119)S(0.139)ELSQAR 150.9 0.00031897 2877700.0 7503.3 8441.3 8399.5 7876.7 12867.0 8329.4 8953.8 7947.8 7990.5 7550.4 True False 8773.460493069815 9279.296477391792 8599.77593528114 7435.394035605951 10345.80371653235 7892.591600929328 8105.631244101675 7739.178671390183 8107.345945959167 8919.227751066483 0.9836569642501575 1.040369944167224 0.9641839153903045 0.8336365258434949 1.1599438881124309 0.8848962960930784 0.9087817320431666 0.8676960480647891 0.9089739798369608 1.0 13.122703088088278 QLLT(ph)LYNPT(ph)GTALR ddPTM_PC-9_Lapatinib_30min_R1 1 QLLTLYNPTGTALR 14 0 F8WF07;C9J3M4;O75425-2;O75425-4;O75425 F8WF07 MOSPD3 Motile sperm domain-containing protein 3 2 QLLT(0.986)LY(0.014)NPT(0.961)GT(0.039)ALR 72.583 0.031873 0.0 25444.0 22501.0 30828.0 29636.0 28541.0 23454.0 22704.0 24857.0 33199.0 21218.0 True False 25081.163894141875 22448.90031695731 28293.44083952132 31815.530302797877 26862.274493764955 22450.92709394437 23879.502028474828 26011.94696493988 29459.779019031517 24885.503028792165 1.0078624436533725 0.9020874639738751 1.136944702575882 1.2784764794984362 1.0794346597167714 0.9021689080573928 0.9595748175492611 1.045265065964085 1.1838128803322554 1.0 14.60301792910443 -6.563208618802236 24.995395673939147 1.0143837790632448 1.0858163778440808 0.07206570523121081 0.11181597242504775 455.1463947865757 282084.8572573313 0.04094647435543426 0.04094654710230252 2.7339551211910276e-07 6.563208618802236 0.07143259878083597 QLLTLS(ph)SELSQAR ddPTM_PC-9_AZD4547_30min_R2 2 QLLTLSSELSQAR 13 0 P15311;E7EQR4 P15311 EZR Ezrin 1 QLLT(0.362)LS(0.491)S(0.147)ELSQAR;QLLT(0.262)LS(0.369)S(0.369)ELSQAR 139.64 6.9292e-05 8781900.0 19038.0 25877.2 31640.0 36826.0 35795.0 31913.0 33303.0 44634.0 38620.0 28472.0 True False 25091.68798500011 34241.4988437734 31220.432926791236 28336.33465602835 30825.482116675314 29917.47506509796 36266.902483540376 37736.84088728455 40661.374355707354 27475.20394620232 0.9132484706621563 1.2462691418349354 1.13631305477922 1.0313421043757187 1.1219382457372469 1.0888900087394333 1.3199866524941033 1.3734871981723946 1.479929846392556 1.0 14.74584256977155 -7.263747240530492 22.075852686352036 1.3244749170773924 1.0977211530323632 0.328826507733574 0.13947372599170363 42.17851859332895 403443.593998555 0.05354349125808442 0.03813782272171648 5.448196457239913e-08 7.263747240530492 -0.22675376404502923 QLLTLS(ph)SELSQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QLLTLSSELSQAR 13 0 P15311;E7EQR4 P15311 EZR Ezrin 1 QLLT(0.157)LS(0.642)S(0.202)ELSQAR;QLLT(0.361)LS(0.623)S(0.017)ELSQAR 155.37 0.00018536 8940500.0 18336.699999999997 17612.300000000003 21553.0 31518.0 33850.0 27731.0 23878.0 18910.3 22230.0 21117.5 True False 21440.74114366655 19360.73274836427 22066.905260207674 29752.14864273468 27217.33549425819 26276.737542364543 21616.10297825057 18413.924662119058 22555.071694971808 24945.935583961975 0.8594883551872492 0.7761077023229188 0.8845892023546609 1.192665175559207 1.0910529052979887 1.053347446277307 0.8665180307828505 0.7381532995682704 0.9041581791573582 1.0 14.606517157415768 -10.72764606334727 9.150841748699932 1.000000004085627 0.9323727838731364 0.023519223974980186 0.13506838485591627 1.1174832136774205e-08 9.703996726188723e-10 0.14898122743636552 0.03613325296124934 1.872207310205104e-11 10.72764606334727 -0.06762722021249057 QLLTLS(ph)SELSQAR ddPTM_PC-9_Lapatinib_30min_R1 3 QLLTLSSELSQAR 13 0 P15311;E7EQR4 P15311 EZR Ezrin 1 QLLT(0.022)LS(0.469)S(0.469)ELS(0.04)QAR;QLLT(0.049)LS(0.923)S(0.029)ELSQAR;QLLT(0.051)LS(0.382)S(0.382)ELS(0.184)QAR 207.64 5.984e-10 5764300.0 27586.9 21914.600000000002 22445.0 20279.2 25628.9 26638.4 24367.3 24373.2 25860.2 24494.5 True False 27193.505747182116 21863.85809012901 20599.658740205534 21770.600017428063 24121.45849035607 25499.137729143353 25628.919563885407 25505.667850741127 22947.55195602151 28728.341688130346 0.9465741546236769 0.7610553483204523 0.7170500463908319 0.7578091437983348 0.8396397798457788 0.8875951840853662 0.8921127380796392 0.8878224899865791 0.7987774653036351 1.0 14.810187096841755 -6.533438215642872 3.657770208553773 0.8856610141342381 0.7878797496215751 0.28185651856650895 0.07252748041319199 0.31142191165440647 9.0649487353636 0.024513630082356352 0.025802798408641518 2.9279373810630737e-07 6.533438215642872 -0.097781264512663 QLLTLSS(ph)ELSQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLLTLSSELSQAR 13 0 P15311;E7EQR4 P15311 EZR Ezrin 1 QLLT(0.004)LS(0.204)S(0.748)ELS(0.044)QAR 134.37 4.6298e-05 2574500.0 7314.5 6617.7 9977.3 10053.0 11189.0 7334.9 8237.9 6484.0 8776.9 7112.3 True False 8552.700382039799 7274.6615211443295 10215.196671120964 9489.763002265743 8996.595770908558 6950.244931646521 7457.546474768836 6313.801870365877 8905.245558236533 8401.703689064174 1.0179721516687341 0.8658555205431935 1.215848243305375 1.1295046044789474 1.070806125026607 0.8272423295162264 0.8876231239237499 0.7514906623741144 1.0599333049352573 1.0 13.036466190475107 -6.750590297293708 24.970912458249124 0.8886238790106035 1.0617316087539483 0.30528927760227065 0.11534105464773999 247.8247009443735 570407.5964818025 0.038896378529565706 0.038527398839556526 1.7758639972266673e-07 6.750590297293708 0.17310772974334487 QLLTLSSELSQAR ddPTM_PC-9_Lapatinib_30min_R1 1 QLLTLSSELSQAR 13 0 P15311;E7EQR4 P15311 EZR Ezrin 0 137.95 0.00028527 4051800.0 13498.0 19828.0 17195.0 11687.0 13784.0 17123.0 12524.0 9208.7 19297.0 12305.0 False True 13305.516044769953 19782.089484228698 15781.293474619466 12546.50096668912 12973.252220386676 16390.689205662562 13172.431439597369 9636.56982001214 17123.568653581457 14431.902854618133 0.9219516081008166 1.370719418188055 1.0935005337546002 0.8693587459033031 0.8989287380239885 1.1357261319436909 0.9127300517673773 0.6677269045591233 1.1865080319676629 1.0 13.816973912083515 -5.588825961519246 6.013676414480855 0.9440561023160097 1.1668201761185906 0.18570602598341157 0.16892901843940994 0.2676899034611524 17.87146538000254 0.04460782969581202 0.07858847812991132 2.5773537947452496e-06 5.588825961519246 0.2227640738025809 QLMEQDAS(ph)SSPSAQVIGLK ddPTM_PC-9_AZD4547_30min_R2 2 QLMEQDASSSPSAQVIGLK 19 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 QLMEQDAS(0.507)S(0.246)S(0.246)PSAQVIGLK;QLMEQDAS(0.293)S(0.293)S(0.293)PS(0.122)AQVIGLK 153.75 2.1866e-05 65124200.0 149877.0 139975.0 156930.0 206246.0 174011.0 165284.0 164020.0 207488.0 148409.0 192448.0 True False 197534.76836473728 185219.18138968624 154849.00566375942 158699.17116893549 149852.57629849928 154948.7653514132 178617.46225115727 175425.49719991256 156253.59675702173 185710.4540966126 1.0636706981609838 0.9973546308455484 0.8338195413770403 0.8545516295295634 0.8069151358627399 0.8343567200089006 0.9618061789792117 0.9446183202408762 0.8413828802321142 1.0 17.50269550483577 -5.077790187806009 4.074618084048078 0.8801929363294246 1.0526472320672131 0.4885397633275963 0.06110973713809314 0.17570783211815783 5.3479180210368105 0.016348586220438575 0.05329256324516166 8.360068042936475e-06 5.077790187806009 0.17245429573778848 QLMEQDAS(ph)SSPSAQVIGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLMEQDASSSPSAQVIGLK 19 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 QLMEQDAS(0.33)S(0.33)S(0.33)PS(0.009)AQVIGLK 137.73 2.4413000000000002e-09 0.0 25108.0 23882.0 27159.0 24013.0 27358.0 26977.0 29605.0 22277.0 24674.0 17240.0 True False 29358.2884943954 26252.847129360496 27806.573561081055 22667.629461196393 21997.396291046232 25562.278629705663 26800.60007836116 21692.252354432567 25034.810571378068 20365.475528235092 1.4415714699955078 1.2890858891540753 1.3653780645843245 1.113041992551048 1.0801317288441712 1.2551771056985936 1.3159820423149111 1.0651483351988518 1.2292769956031382 1.0 14.313837880815258 -1.5228787452803376 0.4036241877419778 1.1431607764135723 6.0632240845004715 0.46146245945069264 0.1008118752300751 72.96031810965309 0.9621499473848012 0.07344068106163879 286.2679838913433 0.029999999999999995 1.5228787452803376 4.920063308086899 QLMEQDAS(ph)SSPSAQVIGLK ddPTM_PC-9_Lapatinib_30min_R1 2 QLMEQDASSSPSAQVIGLK 19 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 QLMEQDAS(0.501)S(0.231)S(0.231)PS(0.038)AQVIGLK;QLMEQDAS(0.459)S(0.266)S(0.266)PS(0.008)AQVIGLK 159.54 7.6561e-06 49748800.0 110822.0 120133.0 133795.0 120368.0 128540.0 116782.0 122919.0 108267.0 133949.0 98211.0 True False 109241.65795773444 119854.83941944975 122794.8915636355 129220.26425587686 120979.52991936337 111787.50609213841 129283.14437271378 113297.48006811518 118862.25307449767 115186.64049206862 0.948388263526589 1.0405272599968098 1.066051505965145 1.121833779541253 1.0502913306833845 0.9704902028098974 1.122379677195428 0.9835991360119274 1.0319100597667152 1.0 16.813613875127686 -9.377629016239135 11.487812047928466 1.00000000066006 1.040046662903431 0.03700510883444663 0.05544473344171442 0.0 0.0 0.05355085401804084 0.012987989850494961 4.1915146049887737e-10 9.377629016239135 0.040046662243371056 QLMEQDASS(ph)SPSAQVIGLK ddPTM_PC-9_AZD4547_30min_R2 5 QLMEQDASSSPSAQVIGLK 19 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 QLMEQDAS(0.217)S(0.356)S(0.356)PS(0.072)AQVIGLK;QLMEQDAS(0.112)S(0.43)S(0.43)PS(0.029)AQVIGLK;QLMEQDAS(0.047)S(0.433)S(0.433)PS(0.087)AQVIGLK;QLMEQDAS(0.029)S(0.415)S(0.415)PS(0.142)AQVIGLK;QLMEQDAS(0.003)S(0.655)S(0.314)PS(0.028)AQVIGLK 207.82 3.0654999999999996e-72 58542300.0 209030.0 206509.0 249535.0 315054.0 298377.0 283880.0 262186.0 334847.0 267409.0 282049.0 True False 275497.1919059025 273258.99574640207 246226.0028567277 242423.167835778 256952.50391192132 266128.9387234039 285520.04607841634 283104.0901685842 281543.6938137067 272174.5503590347 1.012207759845602 1.0039843746813832 0.9046621094144277 0.8906900645780047 0.9440724842677853 0.9777877408903375 1.0490328566788378 1.0401563621401486 1.0344232899156547 1.0 18.054172648599348 -7.078985096886049 3.624928417386026 1.0339136432490537 0.9486689973890405 0.5028794680326778 0.03729632199370573 0.21886511265801734 5.474336449025258 0.016707547354751898 0.012970189312807114 8.337097934539397e-08 7.078985096886049 -0.08524464586001312 QLMEQDASS(ph)SPSAQVIGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QLMEQDASSSPSAQVIGLK 19 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 QLMEQDAS(0.186)S(0.381)S(0.381)PS(0.052)AQVIGLK;QLMEQDAS(0.055)S(0.441)S(0.441)PS(0.062)AQVIGLK;QLMEQDAS(0.038)S(0.353)S(0.353)PS(0.257)AQVIGLK;QLMEQDAS(0.228)S(0.381)S(0.381)PS(0.009)AQVIGLK 142.58 0.00012993 93353700.0 234400.0 235264.0 257755.0 281703.0 303165.0 251177.0 301096.0 253653.0 224665.0 222352.0 True False 274079.29038897046 258619.45511439026 263900.85674128117 265920.0942034484 243761.99453816153 238004.83594816262 272574.0071337356 246994.8775175695 227950.30060057747 262662.6574625364 1.043465001979059 0.9846068627066913 1.0047140285973897 1.0124015982034926 0.9280420631277947 0.9061236121168433 1.037734140691898 0.9403501811170032 0.8678443399708998 1.0 18.00285158270038 -6.252978933787491 24.529516528141293 0.9462245470332422 1.0089202455393735 0.3204639345508308 0.046039929938477046 647.6352415720778 1877698.6989203177 0.013875791035011764 0.017598757787951304 5.584972849662367e-07 6.252978933787491 0.06269569850613133 QLMEQDASS(ph)SPSAQVIGLK ddPTM_PC-9_Lapatinib_30min_R1 3 QLMEQDASSSPSAQVIGLK 19 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 QLMEQDAS(0.103)S(0.356)S(0.356)PS(0.184)AQVIGLK;QLMEQDAS(0.036)S(0.446)S(0.446)PS(0.073)AQVIGLK;QLMEQDAS(0.004)S(0.492)S(0.492)PS(0.012)AQVIGLK 301.34 1.4005999999999993e-254 42580500.0 116973.0 130325.0 142311.0 126023.0 129757.0 128350.0 121246.0 106600.0 143643.0 99334.0 True False 115304.9435697787 130023.24046964417 130610.73891634641 135291.15182040437 122124.94837207724 122860.76969846338 127523.52461876569 111553.02516243281 127464.41271215225 116503.74954576472 0.9897101511268089 1.116043397543774 1.1210861403652954 1.1612600654304233 1.048249080808377 1.0545649404202353 1.0945872996874852 0.9575058794018713 1.0940799176775164 1.0 16.830016861625644 -7.209599146511291 1.1882940704280898 1.0234578430329624 1.0953677555183563 0.1772039083555924 0.05632636819590012 0.7840575169093755 2.177165416567997 0.03632635530446629 0.021689961388951025 6.171643813245825e-08 7.209599146511291 0.07190991248539391 QLMEQDASSS(ph)PSAQVIGLK ddPTM_PC-9_Lapatinib_30min_R1 1 QLMEQDASSSPSAQVIGLK 19 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 QLMEQDAS(0.054)S(0.317)S(0.623)PS(0.007)AQVIGLK 127.91 3.3625e-05 8388600.0 40118.0 43217.0 44357.0 37522.0 47396.0 44522.0 39992.0 42291.0 40240.0 33171.0 True False 39545.90996325983 43116.933691744576 40710.13868297157 40281.49304972266 44608.26046412121 42617.89784585107 42062.59007764114 44255.994250885975 35707.74745401452 38904.56315242083 1.0164851307628446 1.1082744592921006 1.0464103792523471 1.0353925037509681 1.1466074118183607 1.0954472789960932 1.0811736893908241 1.137552787252725 0.9178292868658676 1.0 15.247651759729457 -8.264961961527327 24.99930716687159 0.9589146367979091 1.0838445552013034 0.563324496261927 0.04384581858990855 223.5653253642032 1586576.9140432475 0.036062422427740506 0.010791964889351467 5.432979151453275e-09 8.264961961527327 0.12492991840339429 QLNENKQER ddPTM_PC-9_AZD4547_30min_R2 1 QLNENKQER 9 1 P26368;P26368-2 P26368 U2AF2 Splicing factor U2AF 65 kDa subunit 0 74.376 0.035671 2929700.0 8520.6 8871.4 12774.0 23403.0 15225.0 11953.0 10393.0 16429.0 11069.0 14599.0 False True 11229.973560510138 11738.906560317626 12604.608413616677 18007.799922745646 13111.271552629752 11205.577020434172 11317.9568660912 13890.27555086252 11654.084742188621 14087.89345358977 0.7971364631273955 0.8332620202579972 0.8947120770852272 1.2782464590656764 0.9306765128386769 0.7954047251527766 0.8033817762305154 0.9859725016108143 0.8272411188075117 1.0 13.78216828280346 -6.534790024251892 24.35151371487387 0.8750797521671139 0.9591855024516527 0.050770910538435965 0.13775080611399346 508.2698054756677 1039101.5503927818 0.04854362978209256 0.04858180760661409 2.9188378931594675e-07 6.534790024251892 0.08410575028453882 QLPALDGSLMGPES(ph)PPAQEEEAPVSPHK ddPTM_PC-9_AZD4547_30min_R2 1 QLPALDGSLMGPESPPAQEEEAPVSPHK 28 0 A0A494C108;Q8N9T8 A0A494C108 KRI1 Protein KRI1 homolog 1 QLPALDGS(0.014)LMGPES(0.986)PPAQEEEAPVSPHK 69.726 0.00011569 4676800.0 9371.7 10894.0 18573.0 22675.0 22860.0 25996.0 14977.0 27838.0 19397.0 18300.0 True False 12351.705656530392 14415.2724562189 18326.70988461738 17447.62907525778 19686.2835923229 24370.466010474927 16309.92398570652 23536.276753601007 20422.28582023967 17659.3225700865 0.6994439117077575 0.8162981563424881 1.0377923508606939 0.9880123660469676 1.1147813577894494 1.3800340253004142 0.9235871829723664 1.332796128514556 1.1564591868791962 1.0 14.108142380320533 -5.092745935497841 0.8468142108829417 1.1668193813340113 0.5472214219197977 0.5637268650962931 0.1327848191535493 1.1261121292890541 0.8548334205927208 0.04930407181702309 0.5966319725717483 8.077074050443214e-06 5.092745935497841 -0.6195979594142136 QLPALDGSLMGPES(ph)PPAQEEEAPVSPHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QLPALDGSLMGPESPPAQEEEAPVSPHK 28 0 A0A494C108;Q8N9T8 A0A494C108 KRI1 Protein KRI1 homolog 1 QLPALDGS(0.002)LMGPES(0.998)PPAQEEEAPVSPHK;QLPALDGS(0.014)LMGPES(0.985)PPAQEEEAPVS(0.001)PHK 98.32600000000001 7.965e-10 5374000.0 21451.8 35579.0 38131.4 37515.5 42624.0 29796.5 31687.9 26745.3 24888.8 22970.5 True False 25083.166047637056 39111.04798658053 39040.597190139786 35413.62816189205 34272.133178944176 28233.9190862596 28686.19271147107 26043.264213987764 25252.7516150164 27134.86981562206 0.9243886636668587 1.4413574950731314 1.4387611753959244 1.3050966672227684 1.2630292097149867 1.040503207795189 1.0571708250818983 0.9597711133662474 0.9306383920986387 1.0 14.727860366659574 -6.806694983371735 2.2682767757823044 0.9838134209829053 1.3024353373666948 0.501379338648627 0.13791741261011217 0.24753877737819807 2.612233559507723 0.054908912819306634 0.04921057590997848 1.5606482029789595e-07 6.806694983371735 0.31862191638378956 QLPALDGSLMGPES(ph)PPAQEEEAPVSPHK ddPTM_PC-9_Lapatinib_30min_R1 2 QLPALDGSLMGPESPPAQEEEAPVSPHK 28 0 A0A494C108;Q8N9T8 A0A494C108 KRI1 Protein KRI1 homolog 1 QLPALDGS(0.002)LMGPES(0.998)PPAQEEEAPVSPHK;QLPALDGSLMGPES(1)PPAQEEEAPVSPHK 128.55 5.937099999999999e-11 5344100.0 23372.5 37921.0 55548.0 37282.0 52714.0 60747.0 50256.0 55156.0 57006.0 42898.0 True False 23039.20386400845 37833.196254359296 50981.05786148083 40023.842649106125 49613.46615971152 58148.99241817339 52858.00977550346 57718.749116877516 50585.383980207516 50312.86214200802 0.4579187683455636 0.7519587366660859 1.0132808131166704 0.7954992211760653 0.9860990618994709 1.1557480521391903 1.0505864211483686 1.1471966940375282 1.0054165441320015 1.0 15.618639641934353 -4.572037589055703 0.7428652411558627 1.0635272170744205 1.121738414165533e-16 0.8000933073644123 0.09004475751969522 1.651891173384334 0.5605129994810149 0.03744742137897781 1.5754175017678034 2.67893644747887e-05 4.572037589055703 -1.0635272170744203 down QLPITYPS(ph)AEEDLASHEDSVPSAMTTR ddPTM_PC-9_AZD4547_30min_R2 1 QLPITYPSAEEDLASHEDSVPSAMTTR 27 0 Q8NDX5-2;Q8NDX5;Q8NDX5-7;H7C528 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 1 QLPIT(0.004)YPS(0.994)AEEDLAS(0.002)HEDSVPSAMTTR 66.01 0.00025632 3518500.0 3887.5 3707.5 8291.8 12088.0 9807.3 6983.6 7911.2 8744.8 6586.5 8693.8 True False 5123.64413497678 4905.876870885949 8181.845314234123 9301.298357738295 8445.725681320575 6546.914388011719 8615.281473974856 7393.492095512968 6934.648943393748 8389.432708186776 0.6107259350178593 0.5847686061178582 0.9752560868924928 1.1086921704088144 1.0067099856559867 0.7803762919062398 1.026920624271494 0.8812862982139513 0.8265933090596952 1.0 13.034357543866392 -5.260305169080132 24.977310655272554 0.9507674939074524 0.5977472355595946 0.6973748844735866 0.09301049485021207 53.70440129407602 1182627.8117445486 0.025352750237541223 0.059816701537367734 5.4915485933704095e-06 5.260305169080132 -0.3530202583478578 QLPLEPES(ph)PSGQVGPR ddPTM_PC-9_AZD4547_30min_R2 2 QLPLEPESPSGQVGPR 16 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 QLPLEPES(0.808)PS(0.192)GQVGPR;QLPLEPES(0.996)PS(0.004)GQVGPR 176.42 9.9529e-06 21527000.0 35131.0 37914.0 33791.0 27580.0 25830.0 41423.0 34696.0 42637.0 35132.0 34139.0 True False 46301.9272298056 50168.95905132028 33342.90926135281 21221.857106752344 22243.950358254617 38832.81326172883 37783.876784941785 36048.43135078977 36989.005796600504 32943.80400110288 1.4054821121524255 1.522864786642148 1.0121147290773274 0.6441835650200531 0.6752089211528196 1.178759236803036 1.1469190620390066 1.094240098975302 1.1227909744534117 1.0 15.007719531355237 -5.2829740444753055 8.2580865417005 0.9767801432590083 1.4644584747923786 0.5388343593357001 0.1774929167134262 0.1789002032231495 62.04289938846253 0.0529369034294683 0.11483466499418156 5.212258611357903e-06 5.2829740444753055 0.48767833153337026 QLPLEPES(ph)PSGQVGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 QLPLEPESPSGQVGPR 16 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 QLPLEPES(0.784)PS(0.216)GQVGPR;QLPLEPES(0.587)PS(0.413)GQVGPR;QLPLEPES(0.851)PS(0.149)GQVGPR;QLPLEPES(0.584)PS(0.416)GQVGPR;QLPLEPES(0.878)PS(0.122)GQVGPR 173.34 1.0238e-05 81937000.0 147519.3 187066.8 148032.9 109530.9 151721.7 87000.8 146351.9 118242.5 103967.5 96615.4 True False 172491.40385101413 205637.55562258806 151562.5657538994 103394.23877696902 121992.92202833644 82438.3248918447 132488.38853600112 115138.7596632849 105487.82800031423 114131.00721291466 1.5113456725149763 1.8017676409265828 1.3279701060655242 0.9059259293496299 1.0688850033607007 0.7223131286141518 1.1608448201008184 1.0088297867072202 0.9242696667306516 1.0 16.800331271979914 -5.544617562798011 3.5274401842884617 0.9734472887124174 1.6507215962988242 0.8239907166989964 0.12788261522452699 0.08212348588382613 2.162260091804778 0.03404683923904193 0.06823979829683209 2.8535299633853435e-06 5.544617562798011 0.6772743075864068 QLPLEPES(ph)PSGQVGPR ddPTM_PC-9_Lapatinib_30min_R1 4 QLPLEPESPSGQVGPR 16 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 QLPLEPES(0.88)PS(0.12)GQVGPR;QLPLEPES(0.955)PS(0.045)GQVGPR;QLPLEPES(0.769)PS(0.231)GQVGPR;QLPLEPES(0.763)PS(0.237)GQVGPR 180.93 3.3395999999999998e-06 92220800.0 127233.7 261397.0 250841.0 226995.0 300953.0 275941.0 324665.0 306253.0 282658.0 261240.0 True False 125419.32410619725 260791.75130668396 230217.821254261 243688.96953312174 283251.53623636335 264139.6466798882 341474.56510195433 320482.6324115434 250822.0795193048 306394.9859195814 0.4093386963555458 0.8511619422360039 0.7513759422769589 0.7953425504067553 0.9244653119444571 0.8620886725255229 1.1144913617861234 1.0459787109429382 0.8186233164570694 1.0 18.22503316253472 -4.369656144189508 0.5335449083007141 0.9834734318679041 7.155975381189707e-14 0.6633781911771999 0.10759472615662016 4.065308767202646 0.6403802637959127 0.06099316198586972 2.7327468044760175 4.269173999762981e-05 4.369656144189508 -0.9834734318678325 QLPLEPES(ph)PSGQVGPRPAPPQEES(ph)PSSEAK ddPTM_PC-9_AZD4547_30min_R2 2 QLPLEPESPSGQVGPRPAPPQEESPSSEAK 30 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 2 QLPLEPES(0.934)PS(0.07)GQVGPRPAPPQEES(0.689)PS(0.228)S(0.078)EAK;QLPLEPES(0.934)PS(0.217)GQVGPRPAPPQEES(0.563)PS(0.208)S(0.078)EAK 63.297 0.0011505 24187000.0 84158.0 77053.0 79242.0 106308.0 95715.0 101429.0 91816.0 101529.0 83705.0 101589.0 True False 110918.49340485575 101958.87539645996 78191.19930419693 81800.33304222718 82426.62441116292 95086.62859580187 99987.44612883957 85840.02595431979 88129.47541285561 98032.40003128519 1.131447290584115 1.0400528331849646 0.7976056821953118 0.8344214057405731 0.84081002183827 0.9699510423641242 1.0199428566160826 0.8756291381923279 0.8989831462325798 1.0 16.58097102305475 -5.046492956904503 5.311847337699718 0.90207179627926 1.113156171485233 0.5361705674303043 0.06966393726935804 0.13743449363946686 9.314632014477768 0.01918739462985617 0.058006940398993914 8.984771633502265e-06 5.046492956904503 0.2110843752059729 QLPLEPES(ph)PSGQVGPRPAPPQEES(ph)PSSEAK ddPTM_PC-9_Lapatinib_30min_R1 1 QLPLEPESPSGQVGPRPAPPQEESPSSEAK 30 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 2 QLPLEPES(0.793)PS(0.25)GQVGPRPAPPQEES(0.837)PS(0.094)S(0.026)EAK 70.027 0.00024705 8902400.0 27771.0 18810.0 21776.0 19692.0 18205.0 20591.0 19582.0 16786.0 21409.0 16194.0 True False 27374.98044742234 18766.446600682953 19985.66133779084 21140.215370586302 17134.2176924071 19710.370929965407 20595.860144538143 17565.938840305767 18997.692973235502 18993.111322851357 1.4413110091386885 0.9880659509484528 1.052258421385932 1.1130464625430632 0.9021280084739065 1.037764197498863 1.084385796220678 0.9248584153335372 1.0002412269536183 1.0 14.213188636926 -4.759396429349771 24.999994444470993 1.013208939498217 1.441311553753904 0.8128799773428989 0.061871734537167065 22.16966918067358 271226.5805986142 0.015428233092000336 0.09821195946623903 1.7402176560727522e-05 4.759396429349771 0.42810261425568696 QLPLEPES(ph)PSGQVGPRPAPPQEESPSSEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QLPLEPESPSGQVGPRPAPPQEESPSSEAK 30 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 QLPLEPES(0.5)PS(0.5)GQVGPRPAPPQEESPSSEAK;QLPLEPES(0.5)PS(0.5)GQVGPRPAPPQEESPSSEAK 94.96 1.8012e-12 62544000.0 127582.0 84078.0 95648.0 131966.0 147776.0 133758.0 151523.0 181348.0 163208.0 124153.0 True False 149179.11274063864 92424.70818785577 97928.6110670602 124572.37285954475 118820.35361889229 126743.49501249833 137169.64450847908 176587.80715408875 165594.60824079864 146660.956105393 1.0171699183076104 0.6301930018882315 0.6677210736079415 0.8493901592324611 0.8101703191782412 0.8641938412116879 0.9352839920797099 1.204054656695336 1.1290981092595604 1.0 17.162125324109986 -7.414779557306581 1.964999590680786 1.1241203585711268 0.7860394677983821 0.5879621103796969 0.11254723200371533 0.22444636023395476 1.6938217099216548 0.0632064216367612 0.03533549684171461 3.8478704579437016e-08 7.414779557306581 -0.3380808907727447 QLPLEPESPS(ph)GQVGPR ddPTM_PC-9_AZD4547_30min_R2 2 QLPLEPESPSGQVGPR 16 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 QLPLEPES(0.165)PS(0.835)GQVGPR;QLPLEPES(0.035)PS(0.965)GQVGPR 201.9 1.5519999999999997e-50 38231000.0 210070.0 256120.0 230030.0 176380.0 199969.0 247540.0 267970.0 292650.0 252200.0 231950.0 True False 276867.8902725594 338905.78130042093 226979.651901068 135718.3160438353 172206.7560661953 232061.2846681401 291818.8108733247 247427.66692798847 265530.7771234955 223829.50110008544 1.2369588857223868 1.5141247227677959 1.0140738856383993 0.6063468639156231 0.7693657682290637 1.0367770268333567 1.30375490915667 1.1054292026382666 1.186308220401936 1.0 17.772040672886327 -7.034245909871927 23.904103614891696 1.1594599218919435 1.0181649318252033 0.05464357982864232 0.23984316750782664 1261.0350798827872 880214.8065663142 0.10525572223584058 0.08159045938467786 9.241747317736873e-08 7.034245909871927 -0.14129499006674018 QLPLEPESPS(ph)GQVGPRPAPPQEESPSSEAK ddPTM_PC-9_AZD4547_30min_R2 1 QLPLEPESPSGQVGPRPAPPQEESPSSEAK 30 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 QLPLEPES(0.173)PS(0.801)GQVGPRPAPPQEES(0.011)PS(0.01)S(0.004)EAK 60.541000000000004 0.00044878 35993000.0 42280.0 37573.0 56519.0 71010.0 67188.0 58103.0 47416.0 45859.0 58749.0 54645.0 True False 55724.16052136808 49717.73746993871 55769.52113114143 54639.74159356361 57860.1059492997 54469.81022490473 51635.93214303668 38772.54528498414 61854.35220153938 52731.89518264349 1.0567448852039265 0.9428399509961689 1.0576050972182347 1.0361801221881377 1.0972506440152399 1.032957568398438 0.979216316124979 0.7352769163841086 1.172996949707556 1.0 15.686388227613065 -7.35071293676555 4.812347237363082 0.9471877923457767 1.0364779530167099 0.06955947968685405 0.10604523294010869 0.4700065911677612 18.506327175503472 0.04373388675781168 0.02900785489934337 4.459509189939263e-08 7.35071293676555 0.0892901606709332 QLPLEPESPS(ph)GQVGPRPAPPQEESPSSEAK ddPTM_PC-9_Lapatinib_30min_R1 2 QLPLEPESPSGQVGPRPAPPQEESPSSEAK 30 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 QLPLEPES(0.378)PS(0.621)GQVGPRPAPPQEESPSSEAK;QLPLEPES(0.166)PS(0.792)GQVGPRPAPPQEES(0.026)PS(0.007)S(0.009)EAK 70.718 3.0157e-05 88032000.0 106723.0 70125.0 88462.0 78633.0 76498.0 81874.0 73833.0 71950.0 93501.0 77542.0 True False 105201.11044939891 69962.62987096701 81188.99583319513 84415.93313199835 71998.53804085466 78372.43987761575 77655.71147235643 75293.05966638864 82969.93277082029 90945.03138177961 1.1567548974475963 0.7692847955296178 0.8927260192189119 0.9282083017556764 0.7916709351455479 0.8617561474976552 0.8538752507145142 0.8278963514819704 0.9123085836599415 1.0 16.4727072005304 -4.749655342386496 24.98465682838975 0.8646660080297858 1.1567555545444532 0.6392858001171782 0.06427510750188255 316.20324079422545 670375.936741488 0.014904199569156373 0.2392367096393174 1.7796912189066714e-05 4.749655342386496 0.29208954651466745 QLPLEPESPSGQVGPRPAPPQEES(ph)PSSEAK ddPTM_PC-9_AZD4547_30min_R2 3 QLPLEPESPSGQVGPRPAPPQEESPSSEAK 30 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 QLPLEPESPS(0.001)GQVGPRPAPPQEES(0.731)PS(0.208)S(0.061)EAK;QLPLEPESPSGQVGPRPAPPQEES(0.905)PS(0.083)S(0.011)EAK;QLPLEPESPS(0.001)GQVGPRPAPPQEES(0.726)PS(0.212)S(0.061)EAK 92.147 1.1547e-09 174125000.0 225258.0 196054.0 264479.0 328300.0 301454.0 291273.0 253955.0 281152.0 227296.0 278128.0 True False 296885.35834253335 259424.62145507042 260971.83565249114 252615.50718443768 259602.31557480758 273059.6532646971 276556.50302397663 237706.41863023274 239310.40252601917 268390.8233755749 1.1061680671812106 0.9665927403637138 0.9723575209100874 0.941222594749218 0.9672548126264771 1.017395639055024 1.0304245858546923 0.8856726755429947 0.8916489748650541 1.0 18.033975819235422 -7.763495044550534 24.999977666570935 0.9164956146189545 0.9949642773538915 0.28805266794460826 0.05257307059338614 67.54263837515116 821378.5247796533 0.027148741755183215 0.01406438919212186 1.7238717608846653e-08 7.763495044550534 0.07846866273493702 QLPLEPESPSGQVGPRPAPPQEES(ph)PSSEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QLPLEPESPSGQVGPRPAPPQEESPSSEAK 30 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 QLPLEPES(0.003)PS(0.014)GQVGPRPAPPQEES(0.851)PS(0.085)S(0.048)EAK;QLPLEPES(0.009)PS(0.141)GQVGPRPAPPQEES(0.523)PS(0.141)S(0.187)EAK 79.382 6.0078e-07 73447000.0 125752.0 91248.0 114092.0 151096.0 146529.0 142306.0 148208.0 158504.0 135020.0 113828.0 True False 147039.32988478604 100306.49840297665 116812.3859763195 142630.5809798415 117817.69431722775 134843.22284460446 134168.66530700022 154343.4379488698 136994.4120672554 134464.1153380475 1.0935209703728315 0.7459722480663529 0.8687253523562705 1.0607334203721432 0.876201758521446 1.0028193953874152 0.9978027592692332 1.1478410991724073 1.0188176356409042 1.0 17.036861684160833 -7.120895608634781 1.8107468589859845 1.060001715479178 0.9218431195975114 0.20912943309737309 0.10070404999634744 0.5008422489658885 3.244087895495279 0.049005879333064106 0.03412625002047798 7.570148368108015e-08 7.120895608634781 -0.13815859588166668 QLPLEPESPSGQVGPRPAPPQEES(ph)PSSEAK ddPTM_PC-9_Lapatinib_30min_R1 2 QLPLEPESPSGQVGPRPAPPQEESPSSEAK 30 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 QLPLEPES(0.004)PS(0.01)GQVGPRPAPPQEES(0.895)PS(0.064)S(0.027)EAK;QLPLEPES(0.002)PS(0.005)GQVGPRPAPPQEES(0.789)PS(0.163)S(0.042)EAK 88.43299999999999 3.6626999999999998e-09 138397000.0 217328.0 136556.0 158421.0 145048.0 140774.0 152482.0 134587.0 122457.0 163977.0 113675.0 True False 214228.86286692636 136239.81297197545 145396.23690274425 155715.31378594326 132493.9500923326 145960.70031290286 141555.2563207515 128146.79927125732 145508.1835056395 133323.5722875834 1.6068341043609868 1.0218734064378474 1.0905516137020368 1.1679503565210518 0.9937773779908832 1.0947853992245329 1.061742150258411 0.9611713598165551 1.0913912746935213 1.0 17.024572353257255 -4.759225716987729 24.99995145547371 1.0568658197141771 1.606834812386598 0.8908613187225296 0.05807236483150867 17.549320604011864 198146.7631381405 0.014335034708509473 0.09244040326789799 1.7409018348361888e-05 4.759225716987729 0.5499689926724209 QLPS(ph)PEPCEIQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QLPSPEPCEIQK 12 0 A0A590UK32;A0A590UJW2;A0A590UJD8;Q5VVJ2-2;Q5VVJ2 A0A590UK32 MYSM1 Histone H2A deubiquitinase MYSM1 1 QLPS(1)PEPCEIQK;QLPS(1)PEPCEIQK;QLPS(1)PEPCEIQK 110.25 0.0012151 13257300.0 51325.0 64012.0 54709.0 76275.0 69311.0 64916.0 72359.0 79579.0 61096.0 57717.0 True False 60013.30878504235 70366.68831942996 56013.4700450379 72001.5590368866 55730.00710317665 61511.69068191326 65504.63168620623 77490.1355709201 61989.41341772375 68180.63521247928 0.8802104673565428 1.0320626685295324 0.8215451479804579 1.0560411884180858 0.8173876193658026 0.9021871164769467 0.9607512673073006 1.136541707618718 0.909193838170309 1.0 16.0570744201189 -7.5310604916800425 24.988656632823275 1.0234499725454043 0.9215948931107478 0.18971219003010675 0.0892364732693127 291.69192432071384 890870.3182088116 0.03911292504408079 0.022631463260096546 2.9440115419948256e-08 7.5310604916800425 -0.10185507943465644 QLQAS(ph)PGLGAGATR ddPTM_PC-9_AZD4547_30min_R2 2 QLQASPGLGAGATR 14 0 Q92630 Q92630 DYRK2 Dual specificity tyrosine-phosphorylation-regulated kinase 2 1 QLQAS(1)PGLGAGATR;QLQAS(1)PGLGAGATR 116.04 0.00015031 14726200.0 48579.0 50770.0 57995.0 81410.0 74810.0 60022.0 54442.0 71045.0 50732.0 60756.0 True False 64026.111494028795 67180.40963853805 57225.948406740135 62642.18227196181 64423.922814596466 56268.81485154355 59287.232531871115 60066.62770168767 53413.5899485693 58628.95093268711 1.092056236304454 1.1458572696562321 0.9760697999260163 1.0684513585085695 1.0988414731923595 0.959744528196432 1.0112279273074456 1.0245216185200239 0.9110446136055605 1.0 15.839325621892732 -5.653082163460414 0.38439021126519873 0.9689977255288754 1.1566403888427181 0.41296365671108304 0.05238908827458413 3.1569124248721296 0.6035578910304918 0.05007015283229565 0.2579448742389839 2.2228893060874438e-06 5.653082163460414 0.18764266331384272 QLQAS(ph)PGLGAGATR ddPTM_PC-9_Lapatinib_30min_R1 2 QLQASPGLGAGATR 14 0 Q92630 Q92630 DYRK2 Dual specificity tyrosine-phosphorylation-regulated kinase 2 1 QLQAS(1)PGLGAGATR;QLQAS(1)PGLGAGATR 108.96 0.00063579 14701100.0 153338.0 126013.0 143835.0 111117.0 123065.0 132786.0 111048.0 113934.0 144697.0 109741.0 True False 151151.37200125464 125721.22464071574 132009.4415191565 119288.91485544587 115826.55865509903 127107.05231928437 116797.52207796299 119227.78957651583 128399.70013304031 128709.58562930881 1.1743598680876768 0.976782141174786 1.025637996375433 0.9268067663507593 0.8999062353342224 0.9875492310678411 0.9074500668065759 0.9263318578299125 0.9975923666077133 1.0 16.973759976518295 QLQEERPELS(ph)ESELTR ddPTM_PC-9_AZD4547_30min_R2 1 QLQEERPELSESELTR 16 1 E9PKP7;P17480-2;P17480;E9PLT2 E9PKP7 UBTF Nucleolar transcription factor 1 1 QLQEERPELS(0.887)ES(0.107)ELT(0.006)R 54.875 0.032013 1301500.0 3970.4 3607.0 6302.7 7790.9 6234.2 4998.1 5496.7 6039.3 6057.3 6169.0 True False 5232.9046105496645 4772.892211270567 6219.122079888974 5994.828373205108 5368.688940125078 4685.568016885471 5985.895651481135 5106.06495430787 6377.476511776963 5953.025187697464 0.8790328355008471 0.8017591158751078 1.0446994399992506 1.0070221751445019 0.9018421341841495 0.7870902388534616 1.0055216403000613 0.8577260793151145 1.0713001055256193 1.0 12.53940728319229 -8.26719198712747 24.956912092489283 1.0356500617741318 0.913400523642368 0.2632371099356562 0.0835853147080211 718.6171154741954 3117573.007948697 0.07521383983179639 0.021520252295018628 5.405153262978589e-09 8.26719198712747 -0.12224953813176376 QLS(ph)ADSAEAHSLNVNR ddPTM_PC-9_Lapatinib_30min_R1 1 QLSADSAEAHSLNVNR 16 0 H0Y4E8;Q9Y2K2-7;Q9Y2K2 H0Y4E8 SIK3 Serine/threonine-protein kinase SIK3 1 QLS(0.771)ADS(0.229)AEAHSLNVNR 208.07 3.9969e-17 5573800.0 8373.1 5816.5 13635.0 8047.9 9181.3 6415.5 9044.4 8981.4 10129.0 7948.6 True False 8253.698058561517 5803.032251614696 12513.98293262207 8639.76941300739 8641.273985130307 6141.124020260942 9512.67477741092 9398.708632212689 8988.165356901414 9322.504919156258 0.8853519660366697 0.6224756438251261 1.3423412528222791 0.9267648006550305 0.9269261920552995 0.6587418374692315 1.0203990086252348 1.0081741671060795 0.9641362954319468 1.0 13.186501937920372 QLS(ph)ALHR ddPTM_PC-9_AZD4547_30min_R2 1 QLSALHR 7 0 P61313;A0A2R8YEM3;E7EQV9;E7EX53;A0A2R8Y738;E7ENU7;P61313-2 P61313 RPL15 60S ribosomal protein L15;Ribosomal protein L15 1 QLS(1)ALHR 85.86200000000001 0.010768000000000002 4092200.0 12958.0 12805.0 17922.0 18302.0 17609.0 17027.0 15086.0 20143.0 13842.0 17112.0 True False 17078.374456856374 16943.96583457709 17684.342569973236 14082.75666308126 15164.29430346517 15962.298998321137 16428.624774545526 17030.362190092124 14573.659860996926 16512.91408848744 1.0342435239073378 1.0261039174418145 1.070940142679147 0.8528329153543862 0.9183293888773693 0.9666554862929867 0.9948955518395945 1.031335965222846 0.8825613566994494 1.0 14.01130711942681 -5.724874331391886 24.999996392980748 0.952126849691653 1.0419967178553438 0.40256718972804206 0.05253336172348246 190.69224145232423 130377.40302995058 0.014813446443556118 0.02565663117855552 1.8841942260750953e-06 5.724874331391886 0.0898698681636908 QLS(ph)ALHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QLSALHR 7 0 P61313;A0A2R8YEM3;E7EQV9;E7EX53;A0A2R8Y738;E7ENU7;P61313-2 P61313 RPL15 60S ribosomal protein L15;Ribosomal protein L15 1 QLS(1)ALHR;QLS(1)ALHR;QLS(1)ALHR 89.08 0.0095437 3708100.0 39819.3 33342.8 45329.0 47822.0 48045.0 42815.0 39799.0 41137.0 43211.0 35520.1 True False 46559.92102297588 36652.8528291115 46409.815271189815 45142.68838101586 38630.92714391832 40569.706028500164 36028.95060019238 40057.19733825434 43842.8791278195 41959.61295304312 1.1096365706490419 0.8735269524561535 1.1060591841761482 1.0758604573291681 0.9206692918533371 0.9668751252281951 0.8586578393969523 0.9546607921069774 1.0448828299937831 1.0 15.356713749711993 -6.266392145643228 24.961089311185127 0.9508715692725651 1.033916830976455 0.21546088678324715 0.07704539179807766 665.6854610978972 3354932.068078708 0.02365897276836377 0.02766233712049658 5.415117122801411e-07 6.266392145643228 0.08304526170388993 QLS(ph)ALHR ddPTM_PC-9_Lapatinib_30min_R1 2 QLSALHR 7 0 P61313;A0A2R8YEM3;E7EQV9;E7EX53;A0A2R8Y738;E7ENU7;P61313-2 P61313 RPL15 60S ribosomal protein L15;Ribosomal protein L15 1 QLS(1)ALHR;QLS(1)ALHR 74.173 0.019592 5118000.0 24418.6 25281.0 28425.0 28025.0 26881.0 26515.0 26161.0 20387.1 28605.0 19928.2 True False 24070.3862861772 25222.463397760024 26088.006223673063 30086.051988659394 25299.9124300794 25381.0152594839 27515.488573243907 21334.359092767652 25383.20367599615 23372.762817342642 1.0298477109568287 1.0791391499102065 1.116171264285269 1.2872270267653372 1.0824527946395284 1.085922766505427 1.1772458732532618 0.9127872155934219 1.0860163975634816 1.0 14.512540659981253 -7.751837298443254 24.99993194099266 0.9995513424733009 1.1240358759216436 0.35135466710687757 0.07654923585921909 217.69081950839356 566782.1540773049 0.03722061633525465 0.021132259113629193 1.770772225867651e-08 7.751837298443254 0.12448453344834265 QLS(ph)EEQPSGNGVK ddPTM_PC-9_AZD4547_30min_R2 2 QLSEEQPSGNGVK 13 0 Q9H4Z3 Q9H4Z3 PCIF1 Phosphorylated CTD-interacting factor 1 1 QLS(1)EEQPSGNGVK;QLS(1)EEQPSGNGVK 103.66 0.0041703999999999995 11357000.0 185804.0 169571.0 237149.0 296530.0 263510.0 261400.0 226877.0 283840.0 242438.0 251945.0 True False 244885.80703671387 224381.50960836196 234004.2493095958 228169.58984283084 226926.18501369265 245054.6166771091 247068.61348101354 239979.04999432826 255252.77773301373 243124.4822360896 1.007244539029656 0.9229079175599971 0.9624873939365866 0.938488743479414 0.9333744710799329 1.0079388732194614 1.0162226823421836 0.9870624619419984 1.049885126275135 1.0 17.891335652139873 -6.775726753302828 22.299941045761518 1.0116633762301526 0.9509663046510893 0.5638564393896666 0.02605611539036787 46.20828401349794 72121.15641152546 0.008679347100295703 0.0077035401417578165 1.6759970377436694e-07 6.775726753302828 -0.06069707157906323 QLS(ph)EEQPSGNGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QLSEEQPSGNGVK 13 0 Q9H4Z3 Q9H4Z3 PCIF1 Phosphorylated CTD-interacting factor 1 1 QLS(1)EEQPSGNGVK;QLS(0.988)EEQPS(0.012)GNGVK 78.508 0.014919 17124500.0 90118.0 113619.0 117231.0 123030.0 140517.0 119655.0 121385.0 111899.0 100695.0 91677.0 True False 105373.19748836743 124898.34343818827 120026.23164104318 116137.02796864155 112983.70255972452 113380.081159411 109886.53404870373 108961.76981679101 102167.47387877567 108297.31438526724 0.9729991744162992 1.1532912348487512 1.1083029373567876 1.0723906555566518 1.043273355401829 1.0469334517018754 1.0146745990189827 1.0061354746910895 0.9433980376957023 1.0 16.724637941103296 -7.200472236697235 0.949195955966203 0.975841014976737 1.0830988660103171 0.4230767272061947 0.04536288095233081 0.5208590434249047 0.9258485371500131 0.03277405515334704 0.019804430173935038 6.30271636309265e-08 7.200472236697235 0.1072578510335801 QLS(ph)ESESSLEMDDER ddPTM_PC-9_AZD4547_30min_R2 2 QLSESESSLEMDDER 15 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 QLS(0.975)ES(0.024)ES(0.001)S(0.001)LEMDDER;QLS(0.528)ES(0.012)ES(0.213)S(0.247)LEMDDER 106.31 0.00095662 15184100.0 9794.9 9731.4 16980.9 19718.4 11183.1 22544.4 19885.6 28567.0 25580.0 19633.1 True False 12909.474453423556 12876.884742101018 16755.72217087705 15172.627526243128 9630.51959935722 21134.695104114126 21655.379876488307 24152.62655435446 26932.106577394978 18945.751144850547 0.6813915349528039 0.6796713755844384 0.8844052707528174 0.8008459210848996 0.5083208116546382 1.115537459693623 1.1430203907420287 1.2748307718017897 1.4215380731798075 1.0 14.209586719262438 -6.899700034497477 5.748919467121313 1.2188351888486353 0.7252936942096294 0.7618852138773953 0.13468961679534963 0.10392466921810233 5.025765423847138 0.04905340793768181 0.04320086823977929 1.2597952470207042e-07 6.899700034497477 -0.4935414946390059 QLS(ph)ESESSLEMDDER ddPTM_PC-9_Lapatinib_30min_R1 1 QLSESESSLEMDDER 15 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 QLS(0.989)ES(0.01)ES(0.001)SLEMDDER 176.17 5.5491e-05 8639800.0 8564.0 12245.0 9316.9 11400.0 12519.0 10916.0 15115.0 14942.0 14403.0 13218.0 True False 8441.875789554746 12216.64745483056 8550.900446274045 12238.394029285182 11782.657033300986 10449.148126438853 15897.580741736994 15636.259868452804 12780.782469686153 15502.713688122098 0.5445418111554727 0.7880328373858014 0.5515744287289258 0.7894355965989375 0.760038356531647 0.6740205835346623 1.0254708344331636 1.0086143744261384 0.8244222738550968 1.0 13.920233155160032 -7.255977530090435 24.99170601899764 0.965344739209896 0.6914550846386247 0.6721966307604126 0.09572498406787362 267.98654511556936 1226225.5805624528 0.03623266890859042 0.027228573756561705 5.546544094128103e-08 7.255977530090435 -0.27388965457127135 QLS(ph)LAAT(ph)ASPPQAPSPNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QLSLAATASPPQAPSPNR 18 0 Q8NEQ6 Q8NEQ6 C1orf64 Uncharacterized protein C1orf64 2 QLS(0.765)LAAT(0.727)AS(0.509)PPQAPSPNR;QLS(0.841)LAAT(0.715)AS(0.445)PPQAPSPNR 116.0 0.0033328000000000003 28851400.0 32541.0 35322.0 38349.0 40986.0 47696.0 42548.0 40238.0 41476.0 42606.0 35590.0 True False 38049.548585953526 38828.5347250344 39263.38559939241 38689.68729840484 38350.31118860084 40316.707978526756 36426.36534210763 40387.29894745454 43229.03214736702 42042.185269714995 0.9050326081256875 0.923561286739404 0.9339044901568356 0.9202587127714048 0.9121864370886166 0.9589584299646008 0.8664241667843867 0.9606374808625243 1.0282299045598604 1.0 15.359550039235945 -8.024502392021335 5.538536415782667 1.0095105994334348 0.9190777526984073 0.7373823778735247 0.02307117190828306 0.08828063691006953 8.257796009139378 0.014322661168129967 0.005679454514083679 9.451431867358745e-09 8.024502392021335 -0.0904328467350275 QLS(ph)LEGSGLGVEDLKDNTPSGK ddPTM_PC-9_AZD4547_30min_R2 3 QLSLEGSGLGVEDLKDNTPSGK 22 1 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 QLS(0.954)LEGS(0.045)GLGVEDLKDNTPSGK;QLS(0.576)LEGS(0.423)GLGVEDLKDNT(0.001)PSGK;QLS(0.898)LEGS(0.101)GLGVEDLKDNTPSGK 88.829 9.9716e-05 71443600.0 139873.7 137601.6 173571.0 189709.0 198707.0 195583.0 195509.0 242640.0 171399.0 190739.0 True False 184350.62704630243 182078.62625405277 171269.33513072314 145974.52102483265 171119.96298248888 183353.1640916568 212908.92224888082 205145.56331251372 180458.80122200618 184061.28566643354 1.001571983911887 0.9892282648944772 0.9305016778004435 0.793075635086979 0.9296901429483783 0.9961527945857118 1.156728431391741 1.1145503117059083 0.9804277991899069 1.0 17.48982668531516 -6.97422751625968 4.152202988564208 1.073569810557631 0.9259625592954285 0.4378972034435161 0.07097784988745205 0.19733074045405669 7.770942179067792 0.02844262807717413 0.023960138659775403 1.0611395065203314e-07 6.97422751625968 -0.14760725126220253 QLS(ph)LEGSGLGVEDLKDNTPSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QLSLEGSGLGVEDLKDNTPSGK 22 1 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 QLS(0.99)LEGS(0.01)GLGVEDLKDNTPSGK;QLS(0.58)LEGS(0.42)GLGVEDLKDNTPSGK 83.31700000000001 0.00013312 42070000.0 107221.0 98291.0 93566.0 138093.0 133135.0 107112.0 143757.0 132726.0 113673.0 104705.0 True False 125371.39758871951 108048.68089741099 95796.96829103124 130356.09691354676 107048.15246759426 101494.85816010056 130139.2962494497 129242.08313482162 115335.25257681197 123687.18765567595 1.013616688720679 0.8735640525532855 0.7745100370275511 1.053917542991081 0.8654748684689806 0.8205769739275255 1.052164728748909 1.0449108398729992 0.9324753417297 1.0 16.9163365385106 -7.273374776796536 24.985216716949225 1.011130299438012 0.8987475889448239 0.28267514209704026 0.08348351138483451 1008.370296687504 2110884.566599429 0.034909601174094675 0.023742941392358594 5.328748497529758e-08 7.273374776796536 -0.11238271049318815 QLS(ph)LEGSGLGVEDLKDNTPSGK ddPTM_PC-9_Lapatinib_30min_R1 4 QLSLEGSGLGVEDLKDNTPSGK 22 1 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 QLS(0.968)LEGS(0.032)GLGVEDLKDNTPSGK;QLS(0.965)LEGS(0.035)GLGVEDLKDNTPSGK;QLS(0.966)LEGS(0.034)GLGVEDLKDNTPSGK;QLS(0.999)LEGS(0.001)GLGVEDLKDNTPSGK 110.13 8.5557e-06 62618700.0 178701.0 145089.0 158254.0 129607.0 191436.0 179837.0 179547.0 160455.0 184776.0 158155.0 True False 176152.69097025046 144753.0553347413 145242.96699810578 139138.73113627726 180176.11085765687 172145.7907305223 188843.0651297817 167910.3250697763 163964.58110245963 185491.88102170877 0.9496517583410278 0.7803740764146995 0.7830152252383892 0.7501068530325237 0.9713423027748056 0.9280502725096387 1.0180664732580975 0.9052165741428065 0.8839447861508842 1.0 17.500996515913307 -6.2713087495739375 24.963014837516816 0.9485597320265156 0.8109166450032866 0.5282393253195306 0.06255181738503604 539.8342959413712 1365422.7994735723 0.019545512001075113 0.022422518023475495 5.35415883159325e-07 6.2713087495739375 -0.13764308702322892 QLS(ph)LPLTQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLSLPLTQSK 10 0 Q9C0I1-3;Q9C0I1-2;Q9C0I1 Q9C0I1-3 MTMR12 Myotubularin-related protein 12 1 QLS(0.981)LPLT(0.017)QS(0.002)K 75.73899999999999 0.024094 8720100.0 26457.0 22700.0 22504.0 31800.0 31549.0 29643.0 29680.0 30630.0 30628.0 24480.0 True False 30935.647550430913 24953.50598092634 23040.58070689526 30018.349096991024 25367.199926391484 28088.468896480885 26868.495535408187 29825.99495516762 31075.876557516724 28918.030216426636 1.0697702201327042 0.8629047619831215 0.7967548458334226 1.0380495791839708 0.8772105062668434 0.9713133531662704 0.9291260619869527 1.0313978764094804 1.0746194095842787 1.0 14.819681664418813 -7.7812307213937055 5.34490653328478 1.041753927354432 0.9297587102545488 0.25559080673858625 0.07799876927010047 0.23113142911780546 18.591919485638837 0.041724884315807405 0.020651161545753978 1.654890559949667e-08 7.7812307213937055 -0.11199521709988325 QLS(ph)PEAQAR ddPTM_PC-9_Lapatinib_30min_R1 2 QLSPEAQAR 9 0 A0A0U1RRH6;O94880;O94880-2;B4DG57 A0A0U1RRH6 PHF14 PHD finger protein 14 1 QLS(1)PEAQAR;QLS(1)PEAQAR 75.73899999999999 0.025533 6215200.0 51124.0 61401.0 71886.0 58324.0 62591.0 70446.0 57830.0 59397.0 66539.0 53631.0 True False 50394.962385006605 61258.82975696618 65975.81056798474 62613.341523160394 58909.520438640655 67433.1887976467 60824.154435636825 62156.80145940918 59044.67713326724 62901.04689118448 0.8011784362220116 0.9738920540216246 1.0488825517025089 0.9954260639171586 0.9365427659821154 1.072051931254858 0.9669815915919401 0.9881679961056482 0.9386914853008956 1.0 15.940796408293942 -4.768168866172642 4.614873911142376 0.993929280198052 0.7871548737666194 0.6682062271961882 0.04035834499265387 0.10939106635382034 5.354350314905581 0.009903368563315185 0.07415553704181209 1.7054191441040906e-05 4.768168866172642 -0.20677440643143263 QLS(ph)PQSK ddPTM_PC-9_AZD4547_30min_R2 3 QLSPQSK 7 0 E7ERS3;Q86VM9;H3BRH3 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 QLS(0.99)PQS(0.01)K;QLS(0.962)PQS(0.038)K;QLS(0.976)PQS(0.024)K 99.788 0.011729 460242000.0 804180.0 638190.0 850950.0 1132810.0 965900.0 894730.0 845920.0 861180.0 823370.0 1009000.0 True False 1059892.5120168824 844472.4370143504 839665.8469991465 871658.1562400331 831801.4576476249 838782.3916584179 921205.2412358208 728104.4189476994 866891.6572568303 973675.2171156969 1.0885483099349964 0.8673040272257501 0.8623674837760333 0.8952247535088063 0.8542904687578036 0.8614601428833015 0.9461114189233376 0.7477898236996848 0.8903293850128076 1.0 19.89308109603021 -4.7604870619795046 24.907081573826922 0.8731836306803981 1.0885485754324433 0.49936674641195933 0.06208880888487516 17.219194112138076 450107.28175492404 0.014382907143518883 0.08510919042775902 1.735852974711627e-05 4.7604870619795046 0.21536494475204526 QLS(ph)PQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QLSPQSK 7 0 E7ERS3;Q86VM9;H3BRH3 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 QLS(0.995)PQS(0.005)K;QLS(0.699)PQS(0.301)K 83.883 0.020366 293130000.0 158405.0 162387.0 181446.0 181454.0 201610.0 188734.0 174951.0 187415.0 166251.0 153728.0 True False 185219.8378586391 178507.7081817045 185772.3607777865 171287.72066180533 162105.9677694948 178836.45679278142 158378.3747444473 182495.5548326063 168682.10635900832 181597.66948982122 1.019946117034398 0.9829845761963928 1.0229886831680914 0.9432264254437815 0.8926654633008991 0.9847948891370847 0.8721388065683553 1.0049443660004427 0.9288781449283036 1.0 17.47038616254443 -5.771224095365865 24.63039441460109 0.9431036459466638 1.0060742698252716 0.31143669232743965 0.041944831908378305 182.86479294896313 460313.65087435517 0.011090890270479156 0.016683533334550887 1.6934637499554335e-06 5.771224095365865 0.06297062387860775 QLS(ph)PQSK ddPTM_PC-9_Lapatinib_30min_R1 3 QLSPQSK 7 0 E7ERS3;Q86VM9;H3BRH3 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 QLS(0.915)PQS(0.085)K;QLS(0.997)PQS(0.003)K;QLS(0.934)PQS(0.066)K 104.01 0.010412000000000001 375712000.0 520030.0 540280.0 637750.0 516400.0 605590.0 566940.0 570340.0 564820.0 633130.0 463750.0 True False 512614.2768381769 539029.0148547055 585316.6567861906 554377.7786599009 569970.38683575 542693.2978016892 599869.4145049468 591063.599176786 561820.2322455313 543908.5695919682 0.9424640564548049 0.991028722454358 1.0761306026586162 1.0192481046507256 1.0479158055246913 0.9977656689778015 1.1028864924025 1.086696610829634 1.0329313852638875 1.0 19.053004630908248 -5.011120648896168 3.523675406389214 1.0479146815645843 0.9463751926601724 0.4906861206646068 0.03364041275472219 0.1868726720219458 4.809229734480987 0.008771459076229558 0.03729765712847129 9.747188189740709e-06 5.011120648896168 -0.10153948890441189 QLS(ph)SGVSEIR ddPTM_PC-9_AZD4547_30min_R2 4 QLSSGVSEIR 10 0 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 1 QLS(0.962)S(0.026)GVS(0.012)EIR;QLS(0.919)S(0.081)GVSEIR;QLS(0.966)S(0.034)GVSEIR;QLS(0.979)S(0.02)GVS(0.001)EIR 130.44 0.00021314 2580865000.0 101297.0 89143.0 135556.0 237040.0 159621.0 150471.0 133535.0 220988.0 150958.0 147245.0 True False 133507.33889150945 117956.73146362422 133758.43886928304 182394.09023149282 137460.37940901896 141062.0245830963 145419.3563084274 186839.38239905078 158937.33169313511 142089.99736789017 0.9395970255797876 0.8301550682573265 0.9413642152653744 1.2836518657907348 0.967417706772951 0.99276534025029 1.0234313393075591 1.31493691223949 1.1185680529054056 1.0 17.116445471975524 -5.541257211084555 24.640679801484946 1.100995478576329 0.8850969071699343 0.38784736921638496 0.1145447611732354 193.7207425409374 259727.32863538203 0.0321104971240916 0.05562999708437241 2.8756947788868555e-06 5.541257211084555 -0.21589857140639468 QLS(ph)SGVSEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QLSSGVSEIR 10 0 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 1 QLS(0.98)S(0.02)GVSEIR;QLS(0.967)S(0.033)GVSEIR;QLS(0.786)S(0.191)GVS(0.023)EIR;QLS(0.5)S(0.5)GVSEIR 124.47 0.00041169 1827241000.0 116014.4 137588.3 130016.0 130156.9 136521.4 130419.3 133192.0 155593.0 126452.0 104049.4 True False 135653.3465311526 151247.157134603 133116.07452842587 122864.63086736308 109771.01169707002 123579.88231794388 120575.08953342626 151508.84861441096 128301.12127631943 122912.7325654026 1.1036557702349563 1.2305247306589941 1.0830128966304935 0.9996086516259499 0.8930808827202682 1.0054278327282837 0.9809812784795711 1.2326538142319161 1.0438391417915116 1.0 16.907274847083883 -5.496817223913368 5.19712207217763 1.0248768327123892 1.1664970462724884 0.3142599522047931 0.08519384830583976 0.23524933368584186 17.74246758045306 0.024723049479262616 0.04975944729680851 3.18553789714427e-06 5.496817223913368 0.14162021356009924 QLS(ph)SGVSEIR ddPTM_PC-9_Lapatinib_30min_R1 2 QLSSGVSEIR 10 0 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 1 QLS(0.902)S(0.098)GVSEIR;QLS(0.942)S(0.058)GVSEIR 114.24 0.0012243 94582000.0 45897.0 41414.0 43453.0 42459.0 50495.0 45364.0 54511.0 52663.0 60243.0 45358.0 True False 45242.50036352103 41318.10842746859 39880.46207343066 45581.57649907191 47524.98337698964 43423.88746864896 57333.31285562858 55109.915235733526 53457.79895308635 53198.06986426405 0.8504537942628029 0.7766843521370715 0.7496599439638781 0.8568276370810863 0.8933591669444135 0.8162681010691908 1.0777329516261716 1.0359382469391762 1.0048823028633371 1.0 15.69908628227273 -7.255008647198781 24.99529594957695 1.0326332317455733 0.8230131777828354 0.8473546835066225 0.0427755433310667 202.50049488878412 787090.8510362635 0.018166328285242214 0.013733761762468214 5.558931888203993e-08 7.255008647198781 -0.20962005396273786 QLSADS(ph)AEAHSLNVNR ddPTM_PC-9_AZD4547_30min_R2 2 QLSADSAEAHSLNVNR 16 0 H0Y4E8;Q9Y2K2-7;Q9Y2K2 H0Y4E8 SIK3 Serine/threonine-protein kinase SIK3 1 QLS(0.155)ADS(0.844)AEAHSLNVNR;QLS(0.113)ADS(0.887)AEAHSLNVNR 168.55 3.8546999999999995e-05 10974700.0 10224.900000000001 11107.0 22494.1 31489.0 27913.0 23209.0 16484.3 28393.0 18437.199999999997 23548.9 True False 13476.205508867939 14697.12054077688 22195.813536616144 24229.697550200293 24037.76176345182 21757.737561052163 17951.370765679512 24005.51425623224 19411.75275171019 22724.460178727317 0.593026430677689 0.6467533409015831 0.9767366688601894 1.0662386415181844 1.0577924216635035 0.9574589402752847 0.7899580726887426 1.056373355733402 0.8542228329754474 1.0 14.47195840304592 -5.236317432824415 5.039442649828105 0.9722945119097317 0.6111692594344212 0.7313515087653404 0.08496978390661263 0.09372237399845822 6.847338382683991 0.022741875655973985 0.05971575309894357 5.8034008255983866e-06 5.236317432824415 -0.36112525247531047 QLSADS(ph)AEAHSLNVNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QLSADSAEAHSLNVNR 16 0 H0Y4E8;Q9Y2K2-7;Q9Y2K2 H0Y4E8 SIK3 Serine/threonine-protein kinase SIK3 1 QLS(0.009)ADS(0.991)AEAHSLNVNR;QLS(0.389)ADS(0.61)AEAHSLNVNR 231.37 6.804399999999998e-93 3598400.0 16379.9 10569.2 18396.2 18473.0 19619.7 16586.2 21007.0 12519.3 13071.7 13841.5 True False 19152.693552228255 11618.440326590613 18834.835175977016 17438.017700274067 15775.360626194903 15716.390473663638 19017.064882490555 12190.68164029481 13262.8488832732 16350.854380746285 1.1713573557832695 0.7105708396664422 1.1519174923455808 1.0664896949243188 0.9648034444469735 0.961196895751836 1.16306245775657 0.7455684795682465 0.8111410311922708 1.0 13.997078402346895 -7.773001207113565 24.999986290904012 0.8337660765330529 1.0162758920205968 0.23621784031306958 0.1419788145505533 310.8281135281362 672089.0930383492 0.07343678900850104 0.03575489720633226 1.6865483376519844e-08 7.773001207113565 0.18250981548754386 QLSADS(ph)AEAHSLNVNR ddPTM_PC-9_Lapatinib_30min_R1 1 QLSADSAEAHSLNVNR 16 0 H0Y4E8;Q9Y2K2-7;Q9Y2K2 H0Y4E8 SIK3 Serine/threonine-protein kinase SIK3 1 QLS(0.493)ADS(0.507)AEAHSLNVNR 111.7 0.00042964 4340000.0 10556.0 7590.7 11487.0 6437.0 9666.3 10808.0 6730.4 9748.3 12316.0 8280.1 True False 10405.469504266688 7573.124200521222 10542.583201102292 6910.398453202514 9097.747238676997 10345.767034678558 7078.867179899884 10201.241605918785 10928.842386770444 9711.304252460262 1.071480126022266 0.7798256550970118 1.085599104613722 0.711582942265642 0.9368203283685786 1.0653323967331743 0.7289306354608881 1.050450211498049 1.1253732869096065 1.0 13.245449350872615 -7.966768725941401 24.99937077966814 1.0710953635233549 0.9106161837723817 0.20274345718940823 0.13373506272271043 251.81980519318387 189439.9542295572 0.06835917217522379 0.032838464431748676 1.0795214447998236e-08 7.966768725941401 -0.16047917975097314 QLSDVS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 QLSDVSSPR 9 0 Q9P0K7-4 Q9P0K7-4 RAI14 Ankycorbin 1 QLSDVS(0.911)S(0.088)PR 94.82 0.0056247 4943300.0 31855.0 30981.0 39333.0 44966.0 39006.0 42255.0 29370.0 43156.0 35937.0 36569.0 True False 41984.227374838665 40995.002383524654 38811.41872027436 34599.7834177747 33590.69019256985 39612.78817020381 31983.873102770922 36487.23182622331 37836.55645316044 35288.73044073732 1.1897347070999205 1.1617023868957328 1.0998247382532766 0.9804768543850106 0.9518815149493942 1.122533672236471 0.906348080628277 1.0339627232410276 1.0721994240258048 1.0 15.106919907717558 -5.497244378322561 2.810633422019657 1.0092926017310455 1.1761171883507724 0.5763042415259482 0.0575092155093393 0.18760464072401087 2.943230873900602 0.015883717447275476 0.035934812207515 3.182406271803259e-06 5.497244378322561 0.16682458661972688 QLSDVSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 QLSDVSSPR 9 0 Q9P0K7-4 Q9P0K7-4 RAI14 Ankycorbin 1 QLSDVS(0.006)S(0.994)PR 108.31 0.0024439 5814900.0 62784.0 54248.0 67929.0 94400.0 71206.0 64342.0 57953.0 74135.0 63584.0 59885.0 True False 82748.00601167392 71782.605122541 67028.21707597985 72637.53846546124 61320.276005028216 60318.684568625096 63110.70473016292 62679.13920282384 66944.92043069117 57788.44437757541 1.4319126756729927 1.2421619217421949 1.1598896249574404 1.2569561137667165 1.0611165721017974 1.0437845354430675 1.092099041770586 1.084631017116395 1.1584482183546871 1.0 15.818493413696146 -1.5228787452961259 0.4662279719663337 1.0721129668197127 9.927160519924692 0.7784663060661037 0.05741232440654778 44.123539921954695 0.5117694049205054 0.034960860410171934 375.6739708517275 0.02999999999890938 1.5228787452961259 8.85504755310498 QLSES(ph)ESSLEMDDER ddPTM_PC-9_AZD4547_30min_R2 1 QLSESESSLEMDDER 15 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 QLS(0.004)ES(0.996)ESSLEMDDER 121.03 7.2203e-05 3171800.0 4175.2 5032.6 5405.7 6563.6 6279.0 7957.7 7264.4 8247.7 6585.3 6937.2 True False 5502.82675044503 6659.289532143124 5334.0168859783635 5050.463426609126 5407.269233429369 7460.103761023088 7910.917526992482 6973.207478291363 6933.385513843593 6694.330739519348 0.8220129785281765 0.9947655398665379 0.7967961389313348 0.7544388861449873 0.8077385841586922 1.1143912739451416 1.1817338931718937 1.0416586436528588 1.0357100334037888 1.0 12.708724115112437 -6.761335874446947 24.999998971399528 1.083992154339669 0.8374031409680033 0.7183517606560305 0.07487811515545591 1.5846984288739245 382771.05847225845 0.027375720776798545 0.02572947828459961 1.732463627668698e-07 6.761335874446947 -0.2465890133716656 QLSES(ph)ESSLEMDDER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLSESESSLEMDDER 15 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 QLS(0.031)ES(0.416)ES(0.277)S(0.277)LEMDDER 128.82 1.4867999999999999e-05 22231000.0 51821.0 83662.0 61128.0 54368.0 74075.0 51398.0 76131.0 67702.0 49398.0 50684.0 True False 60593.27178859584 91967.41045710394 62585.52334923094 51321.93722343419 59560.53550183672 48702.598398992166 68919.32053929107 65924.8942361985 50120.352298165424 59872.607985676754 1.0120366195354558 1.5360515192373978 1.0453114613648231 0.8571855970548647 0.9947877252329698 0.8134370630830584 1.151099356750562 1.1010860634627713 0.837116571072963 1.0 15.869608493385547 -5.5025303433055734 24.17170953299896 0.9702709249655077 1.2782035287624425 0.3785899933458853 0.1561224061246772 462.21829178180417 549063.8141128372 0.03907286474383044 0.07967064607930682 3.1439067539725144e-06 5.5025303433055734 0.30793260379693477 QLSES(ph)ESSLEMDDER ddPTM_PC-9_Lapatinib_30min_R1 1 QLSESESSLEMDDER 15 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 QLS(0.004)ES(0.849)ES(0.074)S(0.074)LEMDDER 219.85 4.3126e-18 9681600.0 4995.5 11331.0 8608.2 5699.0 8602.8 9671.3 8095.6 10598.0 9892.8 9580.7 True False 4924.2632539374945 11304.763765674563 7900.467024612927 6118.123471306685 8096.800217755549 9257.681043901432 8514.750555924982 11090.421769901148 8778.56868819768 11236.711229519697 0.43822993697667334 1.0060562681344063 0.7030942473503989 0.5444763460000563 0.72056672565231 0.8238781663785039 0.7577618025420181 0.9869811142575031 0.7812400362426073 1.0 13.455932227640739 -7.363109632837542 1.1197027491990643 0.9222514835963692 0.6956235155342766 0.29454525799272413 0.15173095923894223 0.7209497834129387 1.7252615991002254 0.1086104689411438 0.05674724445494076 4.334014571736942e-08 7.363109632837542 -0.22662796806209262 QLSLAAT(ph)AS(ph)PPQAPSPNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QLSLAATASPPQAPSPNR 18 0 Q8NEQ6 Q8NEQ6 C1orf64 Uncharacterized protein C1orf64 2 QLS(0.493)LAAT(0.813)AS(0.695)PPQAPSPNR;QLS(0.336)LAAT(0.876)AS(0.788)PPQAPSPNR 96.773 0.021694 24201800.0 56835.2 65698.57 66305.5 76008.3 77776.8 66377.74 68108.9 63265.3 60054.04 60395.16 True False 66456.27681363156 72220.68984287701 67886.4745850089 71749.80137323358 62536.994365430466 62896.77446306703 61657.13192626553 61604.65291012628 60932.21672391836 71344.32442017653 0.9314865247338076 1.0122836039141556 0.9515329374372807 1.005683380652244 0.8765517772251087 0.8815946464450577 0.864219157268081 0.8634835834636367 0.8540583602006389 1.0 16.122511044617724 -6.27074508760272 24.78721031059252 0.8814509931116694 0.9761982774574903 0.456752183536845 0.044974497035256 454.678982307372 1211106.6046684827 0.012901592174480688 0.014826740449287132 5.361112396865895e-07 6.27074508760272 0.09474728434582091 QLSLAAT(ph)AS(ph)PPQAPSPNR ddPTM_PC-9_Lapatinib_30min_R1 1 QLSLAATASPPQAPSPNR 18 0 Q8NEQ6 Q8NEQ6 C1orf64 Uncharacterized protein C1orf64 2 QLS(0.3)LAAT(0.894)AS(0.806)PPQAPSPNR 110.57 0.0059242 14725000.0 23720.0 25369.0 24232.0 19744.0 26088.0 25145.0 20798.0 16953.0 22892.0 16534.0 True False 23381.748450284733 25310.2596391667 22239.73849822501 21196.039624053206 24553.55513098139 24069.60696585789 21874.818674604445 17740.698269969256 20313.661896553185 19391.879869829834 1.2057494480801934 1.305198867209608 1.1468583060286959 1.0930368673039434 1.2661771471254917 1.2412209196544028 1.1280401292418072 0.9148519065225074 1.0475344336346406 1.0 14.243165046192754 -7.573738076598948 4.817819246039388 0.9876040664602421 1.2071518723339276 0.7098112178826526 0.06345451589950964 0.11334071820212446 5.689901777653824 0.032117801583356226 0.018274643072468663 2.6684675345390045e-08 7.573738076598948 0.2195478058736855 QLSLPLT(ph)QSK ddPTM_PC-9_AZD4547_30min_R2 2 QLSLPLTQSK 10 0 Q9C0I1-3;Q9C0I1-2;Q9C0I1 Q9C0I1-3 MTMR12 Myotubularin-related protein 12 1 QLS(0.002)LPLT(0.996)QS(0.002)K;QLS(0.11)LPLT(0.879)QS(0.011)K 140.01 0.0002988 155389000.0 154459.0 128936.0 235662.0 292520.0 265330.0 200449.0 217900.0 263860.0 206208.0 221884.0 True False 203573.74905321645 170612.04051909648 232536.96790118451 225084.03338894842 228493.5094291795 187914.89234242516 237292.6778717663 223086.49989960337 217107.73389802466 214115.90869623364 0.9507642392981954 0.7968209441230445 1.086033117843125 1.0512251740634333 1.0671486804529942 0.8776316224546403 1.1082440315465467 1.0418959583993186 1.0139729234507069 1.0 17.70803246560397 -5.266434602217929 24.99860622890209 1.0315928579239635 0.8737925898456771 0.45375245728372937 0.06888893698256505 325.30741365304243 1628009.1659647909 0.0174989752353832 0.03836714218143985 5.4145877674982e-06 5.266434602217929 -0.1578002680782864 QLSLPLT(ph)QSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QLSLPLTQSK 10 0 Q9C0I1-3;Q9C0I1-2;Q9C0I1 Q9C0I1-3 MTMR12 Myotubularin-related protein 12 1 QLS(0.025)LPLT(0.975)QSK;QLSLPLT(1)QSK;QLS(0.04)LPLT(0.939)QS(0.021)K 176.87 0.00032421 151490900.0 397570.0 370867.0 400335.0 494927.0 496535.0 432113.0 435495.0 426057.0 422487.0 329069.0 True False 464870.7486345709 407684.2247853843 409880.5046789417 467197.84476498445 399242.53115632077 409452.2335885391 394241.7608892385 414873.45519470714 428665.07310812135 388726.6047912285 1.1958809685388958 1.0487685168972094 1.054418451495169 1.2018674281784756 1.0270522424641864 1.053316723223618 1.0141877505424977 1.0672628270903177 1.1027417928812524 1.0 18.568396324812326 -6.349647633709591 24.99999992540793 1.0464224290504687 1.1147347230884974 0.34276460908703754 0.054212159875747505 97.34187343304376 27585.780566967947 0.0167460300623053 0.018988213803987814 4.470461574520926e-07 6.349647633709591 0.06831229403802874 QLSLPLT(ph)QSK ddPTM_PC-9_Lapatinib_30min_R1 2 QLSLPLTQSK 10 0 Q9C0I1-3;Q9C0I1-2;Q9C0I1 Q9C0I1-3 MTMR12 Myotubularin-related protein 12 1 QLSLPLT(0.998)QS(0.002)K;QLS(0.001)LPLT(0.999)QSK 168.76 0.0006898 141704000.0 331943.0 260491.0 316660.0 253609.0 267765.0 247637.0 231556.0 242717.0 263022.0 198172.0 True False 327209.4319491086 259887.84909401985 290625.4371429484 272260.25187482353 252015.5891462448 237046.1427800419 243544.83666779034 253994.51790197112 233397.6926155515 232425.7661524086 1.4078018860204486 1.1181542106807707 1.2504011149623424 1.1713858423781391 1.084284213915382 1.0198789346986752 1.0478392335731428 1.092798453917623 1.0041816640178591 1.0 17.826410485691255 -1.5228787452843457 0.3093795632348958 1.009501480492203 4.107715050070182 0.7602959391791588 0.0594688735575184 27.724138509933173 0.39580957252341764 0.05825833738555546 48.040784872362565 0.029999999999723123 1.5228787452843457 3.098213569577979 QLSPEDSS(ph)SPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLSPEDSSSPVK 12 0 Q96AY2;Q96AY2-2 Q96AY2 EME1 Crossover junction endonuclease EME1 1 QLSPEDS(0.019)S(0.949)S(0.032)PVK 168.76 0.00098011 2923500.0 20496.0 20095.0 22304.0 21868.0 24858.0 18210.0 19224.0 17902.0 16472.0 16971.0 True False 23965.56798554756 22089.898796771577 22835.811948391034 20642.806857012565 19987.253344646095 17255.035543127124 17402.96355029269 17432.0914687369 16712.871838037598 20047.707957637926 1.1954268306475893 1.1018665497047806 1.13907345401502 1.029684136492417 0.9969844626069186 0.8606986683758615 0.8680774673626658 0.8695303974684793 0.8336549930472328 1.0 14.291149683203729 -6.210970301708997 1.2217510171897652 0.8746403242173442 1.152798915770874 0.8268480512528357 0.05082724336471135 0.16708686795289274 0.5100836657118427 0.019270848768370902 0.029443156299247517 6.152189416912314e-07 6.210970301708997 0.27815859155352984 QLSPEDSSS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 2 QLSPEDSSSPVK 12 0 Q96AY2;Q96AY2-2 Q96AY2 EME1 Crossover junction endonuclease EME1 1 QLSPEDS(0.036)S(0.166)S(0.798)PVK;QLSPEDS(0.015)S(0.058)S(0.926)PVK 128.95 0.00018969 6126500.0 49708.0 49095.0 59965.0 52422.0 58066.0 64526.0 70877.0 67226.0 56640.0 59435.0 True False 65514.11000936997 64963.9986449483 59169.824919565064 40336.91781182635 50004.538192118176 60491.17901953783 77184.91569305732 56837.76639979815 59633.874767148256 57354.19874060604 1.1422722563986727 1.1326807813802586 1.0316563777164858 0.703294940868354 0.8718548822950533 1.054694867120702 1.3457587654940315 0.9909957361074201 1.0397473258558179 1.0 15.807611485328797 -6.992466996283186 24.647507245080398 1.1086396292647258 0.9719729540044836 0.11832457221816461 0.15073710928187586 324.7813547930614 1062656.8718634539 0.05831429941344453 0.051334603525518434 1.017496686749847e-07 6.992466996283186 -0.13666667526024223 QLSPEDSSS(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLSPEDSSSPVK 12 0 Q96AY2;Q96AY2-2 Q96AY2 EME1 Crossover junction endonuclease EME1 1 QLSPEDSS(0.08)S(0.92)PVK 168.93 5.5709e-18 0.0 23323.0 29095.0 26287.0 21662.0 26068.0 22424.0 26377.0 21925.0 19310.0 15714.0 True False 27271.123249752418 31983.35931784372 26913.78177400266 20448.348369151554 20960.16253070377 21248.0459648041 23878.379607057344 21349.491981457726 19592.372219069082 18562.82380804445 1.4691257931314368 1.7229792001787627 1.4498754097067499 1.101575308832592 1.1291473079446241 1.1446559092801372 1.2863549131306913 1.1501209192216562 1.0554629199560932 1.0 14.18012857191055 -5.631378267774381 3.8767843242372235 1.1380697474094537 1.5956023048133072 0.821730467911318 0.09163645601944054 0.08418583854200115 2.353691792926066 0.024996321750944614 0.04574569067370402 2.336801012967871e-06 5.631378267774381 0.45753255740385357 QLSPEDSSS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 2 QLSPEDSSSPVK 12 0 Q96AY2;Q96AY2-2 Q96AY2 EME1 Crossover junction endonuclease EME1 1 QLSPEDS(0.029)S(0.076)S(0.896)PVK;QLSPEDS(0.103)S(0.058)S(0.838)PVK 85.45 0.0096589 13804300.0 62440.0 94420.0 80465.0 81569.0 101733.0 85890.0 78980.0 89921.0 84161.0 85667.0 True False 61549.594149906414 94201.37629114771 73849.47830388231 87567.85636620734 95749.26495477342 82216.68491936903 83069.19794789195 94099.05793274967 74681.90192538065 100474.42680589769 0.6125896519799161 0.9375656999082103 0.735007709439826 0.871543726597973 0.9529714973119219 0.8182846872886369 0.8267695630488128 0.9365473476602725 0.7432926397246881 1.0 16.61646882146126 -1.5228787704318796 0.03418773207439487 1.4024870514058958 3.031616719349558e-06 0.24111029140351248 0.09963689610016897 1697.6555195986862 4.455095923722782 54.74327312062368 149.72933350316086 0.02999999826259308 1.5228787704318796 -1.4024840197891764 QLSQHEENELAEEPEALADGLCS(ph)MKLSPPCK ddPTM_PC-9_AZD4547_30min_R2 1 QLSQHEENELAEEPEALADGLCSMKLSPPCK 31 1 A0A499FJN1;A0A499FIS5;Q9BUB5-2;Q9BUB5;Q7Z319 A0A499FJN1 MKNK1;DKFZp686E14208 MAP kinase-interacting serine/threonine-protein kinase 1 1 QLSQHEENELAEEPEALADGLCS(0.5)MKLS(0.5)PPCK 53.262 0.0018219000000000002 12684000.0 7418.8 5238.7 22867.0 33783.0 27818.0 23439.0 15832.0 27613.0 17142.0 24318.0 True False 9777.824079373824 6932.00732663796 22563.768638967627 25994.851292147003 23955.950873632453 21973.35562469308 17241.017329352035 23346.045333615366 18048.09112391341 23466.634221823137 0.4166692158298865 0.29539844790316966 0.961525561172472 1.1077366718390622 1.0208515906961326 0.936365880892226 0.7347034588078465 0.9948612618636367 0.769095855558584 1.0 14.518323313029763 -5.2638721088148674 24.96707019057365 0.9417835748159801 0.3560337954874554 0.8194578863609222 0.1097607491974608 77.14893688576231 791788.2420483805 0.029907223977996663 0.06735067351452934 5.446630217783974e-06 5.2638721088148674 -0.5857497793285247 QLSQHEENELAEEPEALADGLCS(ph)MKLSPPCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLSQHEENELAEEPEALADGLCSMKLSPPCK 31 1 A0A499FJN1;A0A499FIS5;Q9BUB5-2;Q9BUB5;Q7Z319 A0A499FJN1 MKNK1;DKFZp686E14208 MAP kinase-interacting serine/threonine-protein kinase 1 1 QLSQHEENELAEEPEALADGLCS(0.5)MKLS(0.5)PPCK 65.801 5.2924e-05 4750400.0 5109.1 5281.1 10619.0 17056.0 20026.0 19600.0 17286.0 17491.0 17501.0 12505.0 True False 5973.969720675305 5805.3727064259965 10872.197232781755 16100.407616298084 16102.049057843862 18572.141496171964 15648.54494019763 17031.879783246386 17756.91901636086 14772.057510474466 0.40441013152293276 0.3929968931077857 0.735997488844907 1.089923161000539 1.0900342790045554 1.2572481174679262 1.0593341468581252 1.1529795203660385 1.2020613244817053 1.0 13.85058316390713 -5.547942930759051 2.029754103134024 1.1384597512750152 0.3793001957073921 0.9461298038748059 0.06982972380278749 0.06334761748036816 0.5145781590287933 0.01973824274861463 0.04927864112430809 2.831764084361256e-06 5.547942930759051 -0.7591595555676232 down QLSQHEENELAEEPEALADGLCS(ph)MKLSPPCK ddPTM_PC-9_Lapatinib_30min_R1 1 QLSQHEENELAEEPEALADGLCSMKLSPPCK 31 1 A0A499FJN1;A0A499FIS5;Q9BUB5-2;Q9BUB5;Q7Z319 A0A499FJN1 MKNK1;DKFZp686E14208 MAP kinase-interacting serine/threonine-protein kinase 1 1 QLSQHEENELAEEPEALADGLCS(0.5)MKLS(0.5)PPCK 83.21600000000001 6.4942e-08 5142700.0 21684.0 11680.0 33051.0 18627.0 28952.0 38535.0 15920.0 25259.0 42989.0 17880.0 True False 21374.782183641408 11652.95567761706 30333.674360549485 19996.891717850434 27249.100281822062 36886.94787947242 16744.259702841748 26432.625352513038 38147.126125761184 20970.534176397574 1.0192769532642052 0.5556823483653798 1.4464903042236361 0.9535709271706116 1.2993994360187087 1.7589894262678745 0.7984660553705629 1.260465047297797 1.8190822324734073 1.0 14.356075990808673 -5.266604122041691 24.97990328974618 1.288581474818607 0.7874796431235044 0.275362328428328 0.3273747098238581 495.02070551791553 2394238.171801986 0.08377724205132907 0.18328879913048382 5.412474683206695e-06 5.266604122041691 -0.5011018316951027 QLSQHEENELAEEPEALADGLCSMKLS(ph)PPCK ddPTM_PC-9_AZD4547_30min_R2 2 QLSQHEENELAEEPEALADGLCSMKLSPPCK 31 1 A0A499FJN1;A0A499FIS5;Q9BUB5-2;Q9BUB5;Q7Z319 A0A499FJN1 MKNK1;DKFZp686E14208 MAP kinase-interacting serine/threonine-protein kinase 1 1 QLSQHEENELAEEPEALADGLCS(0.216)MKLS(0.784)PPCK;QLSQHEENELAEEPEALADGLCS(0.247)MKLS(0.753)PPCK 96.351 9.667200000000001e-13 17435600.0 31003.0 22030.0 85830.0 165755.0 127476.0 108500.0 61804.0 119528.0 85180.0 117968.0 True False 40861.30909753958 29150.766679869874 84691.83811967427 127542.74563922184 109778.15779592996 101715.47784799714 67304.43626978733 101057.69408019334 89682.44090158338 113837.97622666474 0.35894268724682815 0.2560724254428705 0.7439682338611053 1.1203883788769162 0.9643368710047058 0.893510946166767 0.5912300842012187 0.8877327007199745 0.7878077586605645 1.0 16.79662239389358 -5.3567171823225435 4.204955920955827 0.8808333315408475 0.30706251286834085 0.7443626581352503 0.13450220762102563 0.11075802281816093 3.409522249225002 0.038177967394435686 0.08593940898642978 4.398279433303156e-06 5.3567171823225435 -0.5737708186725067 down QLSS(ph)GVSEIR ddPTM_PC-9_AZD4547_30min_R2 2 QLSSGVSEIR 10 0 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 1 QLS(0.026)S(0.767)GVS(0.207)EIR;QLS(0.03)S(0.693)GVS(0.277)EIR 152.96 0.00013238 2758820000.0 69885.0 72657.0 100587.0 170373.0 130073.0 124930.0 95102.0 159161.0 105759.0 107741.0 True False 92106.97630169822 96141.95436492524 99253.15065762169 131096.1370866104 112014.60917341258 117118.10735069386 103565.89376301423 134566.32460593033 111349.20482872216 103969.02038380792 0.8859078979649876 0.9247173245454406 0.9546415873807668 1.260915382319282 1.0773844820303575 1.1264712018863436 0.9961226274970609 1.2942925124154352 1.0709844568860016 1.0 16.66579418744994 -5.603608771665009 7.631275976501631 1.12360333972906 0.9137408107110732 0.4902137309533917 0.09240189526297445 0.17752944839674328 14.31301263101322 0.02402905750534004 0.04179864284632183 2.491100382043105e-06 5.603608771665009 -0.20986252901798674 QLSS(ph)GVSEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QLSSGVSEIR 10 0 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 1 QLS(0.291)S(0.709)GVSEIR;QLS(0.04)S(0.941)GVS(0.019)EIR 138.2 0.00011874 1372371000.0 101209.0 130351.0 105031.0 130620.0 147482.0 118108.0 132050.0 142372.0 111790.0 96887.0 True False 118341.68473113187 143291.38582025253 107535.33737228555 123301.78487575396 118583.96080839564 111914.20856274881 119541.26804079021 138634.88585560324 113424.71726409812 114451.84614292972 1.0339866827778772 1.2519796809682513 0.939568394886294 1.0773245607744262 1.0361035213036727 0.9778279017272308 1.0444678008208337 1.2112944485183164 0.9910256678817666 1.0 16.804381208625898 -5.263656685803813 24.99996697858727 1.0421376858303768 1.1429831741401402 0.20125524455064037 0.08526352322940077 302.3145824956637 3408613.029492699 0.02162441122176031 0.04901226564508382 5.449332578927951e-06 5.263656685803813 0.10084548830976336 QLSS(ph)GVSEIR ddPTM_PC-9_Lapatinib_30min_R1 4 QLSSGVSEIR 10 0 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 1 QLS(0.038)S(0.955)GVS(0.007)EIR;QLS(0.097)S(0.901)GVS(0.002)EIR;QLS(0.238)S(0.762)GVS(0.001)EIR;QLS(0.047)S(0.929)GVS(0.024)EIR 153.49 0.00011874 4229860000.0 483330.0 373549.0 483623.0 268453.0 557530.0 424586.0 555285.0 482938.0 472518.0 401130.0 True False 476437.62556813436 372684.0702412818 443861.38377876603 288195.9291529563 524737.1815461541 406427.4465383073 584034.9402696287 505377.06253184687 419298.0470048709 470464.7860278722 1.0126956144596726 0.7921614567327098 0.9434529362469011 0.6125770465972398 1.1153591025940603 0.8638849465647976 1.2413999041259343 1.0742080545469483 0.8912421491627431 1.0 18.84372721668032 -6.299081425383248 24.99871635933298 1.036888775149264 0.8441622988678884 0.30713869765214974 0.14017031588833864 681.2915556561119 452455.3995136141 0.04224263140336325 0.047899714674281 5.022484147047282e-07 6.299081425383248 -0.19272647628137551 QLSS(ph)SSSYSGDISR ddPTM_PC-9_Lapatinib_30min_R1 1 QLSSSSSYSGDISR 14 0 A0A0A0MS99;I3L4X2;P33527-8;P33527-6;P33527-7;P33527-5;P33527-4;P33527-2;P33527-3;P33527;P33527-9 A0A0A0MS99 ABCC1 Multidrug resistance-associated protein 1 1 QLS(0.292)S(0.505)S(0.06)S(0.06)S(0.06)Y(0.003)S(0.013)GDIS(0.007)R 81.71300000000001 0.045696 0.0 13579.0 16974.0 12313.0 8239.2 11533.0 7519.3 12193.0 9969.2 10356.0 5641.3 True False 13385.360969916379 16934.697745879443 11300.672669554491 8845.138253165476 10854.651614750395 7197.717067344419 12824.293879192799 10432.405426353891 9189.598226485445 6616.391188440248 2.0230606970915592 2.5595067255797552 1.7079813372126986 1.336852371821539 1.6405698069538233 1.0878614734751215 1.9382611326849322 1.5767516051016979 1.3889139811655855 1.0 12.691828819796827 -5.437671713644725 4.672301357587339 1.467220148117588 2.2819223697545183 0.5923024493395217 0.28248240872609803 0.14385857311347697 5.436759611057878 0.07166992731333047 0.1533064768562472 3.6502977132077938e-06 5.437671713644725 0.8147022216369304 QLSSGVS(ph)EIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QLSSGVSEIR 10 0 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 1 QLS(0.001)S(0.034)GVS(0.964)EIR;QLS(0.133)S(0.318)GVS(0.549)EIR 152.67 0.00017102 544032000.0 48155.0 48609.0 61755.0 47277.0 60535.0 47823.0 62450.0 78040.0 56121.0 39530.0 True False 56306.69039539634 53434.58027431052 63227.47340714171 44628.22296410202 48673.60130413349 45315.07769242 56534.283901153685 75991.53269021497 56941.66345449905 46696.476080692184 1.2058017032826538 1.1442957747384364 1.3540095252130744 0.9557085825273797 1.042339923467133 0.9704175024709552 1.210675593667103 1.6273504784151271 1.2193995828743702 1.0 15.511026061545774 -7.527335888401117 24.999412290732202 1.337827625496693 1.1122985653485153 0.1321711668743889 0.18157970834279222 188.85579304526698 1059236.0976959127 0.08344677179729892 0.04841771979666586 2.969368599227533e-08 7.527335888401117 -0.22552906014817764 QLSSSS(ph)SYSGDISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLSSSSSYSGDISR 14 0 A0A0A0MS99;I3L4X2;P33527-8;P33527-6;P33527-7;P33527-5;P33527-4;P33527-2;P33527-3;P33527;P33527-9 A0A0A0MS99 ABCC1 Multidrug resistance-associated protein 1 1 QLS(0.002)S(0.001)S(0.058)S(0.584)S(0.204)Y(0.123)S(0.028)GDISR 139.32 0.00010091 19773000.0 25115.0 22387.0 31372.0 15344.0 45221.0 17736.0 16035.0 11838.0 16884.0 18366.0 True False 29366.473456139112 24609.43340947127 32120.02745897254 14484.325425919193 36360.269671664675 16805.892937556426 14516.04871665331 11527.265043397792 17130.896558610184 21695.610414824 1.353567514102937 1.1343047251925364 1.4804850771576277 0.6676154829929312 1.675927479174346 0.7746218067260938 0.6690776815726236 0.5313178483109899 0.7896019623815297 1.0 14.405115557086946 -6.924701496180909 11.354186838067632 0.7103549063719304 1.23415989154144 0.4688470821808478 0.26925483171912423 0.4360886104498625 63.61442495023423 0.08894559757740753 0.07844717955957684 1.189319402003055e-07 6.924701496180909 0.5238049851695096 QLSSSSS(ph)YSGDISR ddPTM_PC-9_AZD4547_30min_R2 2 QLSSSSSYSGDISR 14 0 A0A0A0MS99;I3L4X2;P33527-8;P33527-6;P33527-7;P33527-5;P33527-4;P33527-2;P33527-3;P33527;P33527-9 A0A0A0MS99 ABCC1 Multidrug resistance-associated protein 1 1 QLS(0.038)S(0.038)S(0.348)S(0.129)S(0.436)YS(0.011)GDISR;QLS(0.016)S(0.016)S(0.056)S(0.191)S(0.57)YS(0.15)GDISR 236.75 6.184e-27 47599000.0 34254.0 69551.0 78779.0 76311.0 78774.0 46834.0 57565.0 75192.0 50741.0 42684.0 True False 45146.05947253882 92032.00060606578 77734.3389867159 58718.67794319715 67837.58983821711 43905.462576341844 62688.17348181847 63572.804140267544 53423.06567019545 41189.64615199843 1.096053588465907 2.234347929730894 1.8872300747585908 1.4255688851152768 1.6469573345661235 1.0659344441639893 1.5219400829637129 1.5434170982112974 1.297002296962036 1.0 15.329994112044771 -6.121898121725329 1.8595220852938346 1.3513222811737342 1.7712417605535973 0.21488237709193825 0.32599422464865474 0.5142429504811696 3.52092141922104 0.1071347242729876 0.1571156633927788 7.552693805426629e-07 6.121898121725329 0.41991947937986307 QLSSSSS(ph)YSGDISR ddPTM_PC-9_Lapatinib_30min_R1 1 QLSSSSSYSGDISR 14 0 A0A0A0MS99;I3L4X2;P33527-8;P33527-6;P33527-7;P33527-5;P33527-4;P33527-2;P33527-3;P33527;P33527-9 A0A0A0MS99 ABCC1 Multidrug resistance-associated protein 1 1 QLS(0.301)S(0.043)S(0.018)S(0.048)S(0.479)YS(0.111)GDISR 197.51 9.404600000000001e-08 17178000.0 55241.0 62452.0 30411.0 15972.0 23843.0 18912.0 16666.0 13627.0 24865.0 9496.9 True False 54453.25321004127 62307.39623103942 27910.72496985477 17146.63416103007 22440.60161714159 18103.17784602523 17528.883932635705 14260.1601678093 22064.441859942115 11138.426511176183 4.888774294592098 5.593913661729582 2.5058050113137105 1.5394126040895733 2.0147012322274533 1.6252904149307523 1.57373071636711 1.2802670245658847 1.980929877106329 1.0 13.443257821845192 -5.376366946551164 3.459418628738516 1.6214448665309866 5.265146786743998 0.9457906117906048 0.34508743360395155 0.045499635294451335 0.9924118638691294 0.0901106870633767 0.212607691614829 4.2037129579680074e-06 5.376366946551164 3.6437019202130108 QLSSSSSYS(ph)GDISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLSSSSSYSGDISR 14 0 A0A0A0MS99;I3L4X2;P33527-8;P33527-6;P33527-7;P33527-5;P33527-4;P33527-2;P33527-3;P33527;P33527-9 A0A0A0MS99 ABCC1 Multidrug resistance-associated protein 1 1 QLS(0.034)S(0.034)S(0.034)S(0.017)S(0.163)YS(0.717)GDISR 172.91 0.00016067 15386000.0 25040.0 22308.0 23690.0 21236.0 49725.0 19071.0 24292.0 23780.0 18874.0 17647.0 True False 29278.777437456607 24522.590811564096 24254.859444825317 20046.215768040933 39981.74320389923 18070.883187423242 21990.885901150126 23155.8001969927 19149.996543900048 20846.261406424856 1.4045097519708178 1.1763543751785723 1.1635112393510485 0.9616216249625773 1.9179335049294153 0.8668644624140501 1.054907902784549 1.110789112039823 0.9186297806856621 1.0 14.347501051754941 QLSSSSSYS(ph)GDISR ddPTM_PC-9_Lapatinib_30min_R1 1 QLSSSSSYSGDISR 14 0 A0A0A0MS99;I3L4X2;P33527-8;P33527-6;P33527-7;P33527-5;P33527-4;P33527-2;P33527-3;P33527;P33527-9 A0A0A0MS99 ABCC1 Multidrug resistance-associated protein 1 1 QLSSS(0.001)S(0.012)S(0.038)Y(0.003)S(0.947)GDISR 158.14 0.00041045 4530100.0 13338.0 15876.0 8214.6 6888.4 8620.3 6908.1 6131.8 6086.7 10430.0 4187.2 True False 13147.797674110365 15839.240097418538 7539.227297272997 7394.995915028772 8113.270902161872 6612.656666567628 6449.274600872173 6369.510302590796 9255.263567230893 4910.951940906706 2.677240142505425 3.2252891675608923 1.535186535725095 1.5058172028585233 1.6520770310498953 1.3465121927759565 1.3132432730916621 1.2970011474831897 1.884617010836009 1.0 12.261786988898665 -5.2701586593213 24.080594835466755 1.454214682517043 2.9512646676629672 0.849369955019619 0.25422307061283517 110.0345234468189 303890.6732123441 0.06288604893107302 0.13440919589535674 5.3683564020910105e-06 5.2701586593213 1.4970499851459242 QLT(ph)QPETHFGR ddPTM_PC-9_AZD4547_30min_R2 4 QLTQPETHFGR 11 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3;H0Y5J4;Q9UJU6-5;Q9UJU6 B4DDD6;H0Y5J4 DBNL Drebrin-like protein 1 QLT(0.999)QPET(0.001)HFGR;QLT(1)QPETHFGR;QLT(0.975)QPET(0.025)HFGR;QLT(1)QPETHFGR 115.06 0.002928 30925500.0 124933.0 135763.0 162598.0 173275.0 303297.0 248754.0 134662.0 236509.0 198199.0 186888.0 True False 164659.09523216847 179645.73475983535 160441.84428035427 133329.1258220634 261189.44683730387 233199.37305622685 146646.65712513943 199961.96848614924 208675.39450872215 180345.10800428028 0.9130222441534731 0.9961220281925899 0.8896379062111647 0.739299930547043 1.4482757515723956 1.2930729069218343 0.8131446355709241 1.1087740094475054 1.1570892985007915 1.0 17.4604007639128 -6.233403564410057 24.99649758881151 1.1338031721209585 0.8928576117182301 0.3516825922154707 0.16757515850901075 946.2936880706518 843707.4335944905 0.05249692363108201 0.06776030381289712 5.842469253929886e-07 6.233403564410057 -0.2409455604027284 QLT(ph)QPETHFGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QLTQPETHFGR 11 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3;H0Y5J4;Q9UJU6-5;Q9UJU6 B4DDD6;H0Y5J4 DBNL Drebrin-like protein 1 QLT(1)QPETHFGR;QLT(1)QPETHFGR;QLT(1)QPETHFGR;QLT(0.951)QPET(0.049)HFGR 123.95 0.0011246 35760500.0 189107.0 231833.0 261371.0 220660.0 268047.0 194639.0 151587.0 167902.0 142239.0 116435.0 True False 221119.08006649747 254847.84810907897 267603.07589503785 208297.13558937196 215525.11454148937 184431.78819762327 137227.58196515936 163494.75040687408 144318.97628524946 137543.74380104744 1.6076273188138535 1.852849435868985 1.9455852261962348 1.5144064705019735 1.5669568719406057 1.3408955078640135 0.9977013724713979 1.1886745691855234 1.0492587470499726 1.0 17.06953099437105 -6.719464089359442 1.0967007771293187 1.0499811636327745 1.7899884648527717 0.8679578961338562 0.1193851727324332 0.16667767676832246 0.4275144671270634 0.06361317992554394 0.05994769627666896 1.907813469423635e-07 6.719464089359442 0.7400073012199972 QLT(ph)QPETHFGR ddPTM_PC-9_Lapatinib_30min_R1 3 QLTQPETHFGR 11 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3;H0Y5J4;Q9UJU6-5;Q9UJU6 B4DDD6;H0Y5J4 DBNL Drebrin-like protein 1 QLT(0.998)QPET(0.002)HFGR;QLT(0.987)QPET(0.013)HFGR;QLT(1)QPETHFGR 99.161 0.009807399999999999 25989700.0 174416.0 160983.0 244197.0 262348.0 219610.0 125904.0 148498.0 138416.0 243381.0 212601.0 True False 171928.79585602257 160610.25375426575 224120.06528767993 281641.947087273 206692.97156987205 120519.37941655878 156186.49983370546 144847.31267245082 215968.86886445066 249348.7995769744 0.6895112234255929 0.6441188168009813 0.8988215129485462 1.1295099377461797 0.8289310873785282 0.48333651343428363 0.6263775887378613 0.5809023862083451 0.8661315764537327 1.0 17.927805731987604 -5.2207219027114276 24.67117972474075 0.7818246792138457 0.6668149453801622 0.06975229974226771 0.18605360548607566 1601.377879256284 970286.9235971875 0.05256551792146464 0.13907175377844527 6.015588179586865e-06 5.2207219027114276 -0.11500973383368351 QLTACPELPHNVQEILGLAPPAEPHS(ph)PSPTASPLPLSPTR ddPTM_PC-9_AZD4547_30min_R2 1 QLTACPELPHNVQEILGLAPPAEPHSPSPTASPLPLSPTR 40 0 Q9HA65-2;Q9HA65 Q9HA65-2 TBC1D17 TBC1 domain family member 17 1 QLTACPELPHNVQEILGLAPPAEPHS(0.79)PS(0.193)PT(0.011)AS(0.005)PLPLS(0.001)PTR 73.74 5.6284e-08 2936800.0 3183.3 2050.2 3238.5 3797.6 3329.6 4007.8 3622.4 5073.6 3409.0 4080.7 True False 4195.523183246711 2712.8870561538433 3195.5553740016885 2922.1219923351227 2867.342513079542 3757.191632435042 3944.786582481359 4289.591699729506 3589.1927803885674 3937.835935068411 1.065438797458133 0.6889284116674894 0.8115003841433971 0.7420629098109842 0.728151847959031 0.9541259956961029 1.0017650931952367 1.0893271762615941 0.9114632604230662 1.0 11.94318728909761 -6.901385353316975 5.134529840114975 1.004245504117939 0.7979605415860875 0.44276938202489124 0.1038346426835987 0.18324383475474476 7.766865103008056 0.03615435665972823 0.0317832860588709 1.2549159715516084e-07 6.901385353316975 -0.20628496253185147 QLTACPELPHNVQEILGLAPPAEPHS(ph)PSPTASPLPLSPTR ddPTM_PC-9_Lapatinib_30min_R1 1 QLTACPELPHNVQEILGLAPPAEPHSPSPTASPLPLSPTR 40 0 Q9HA65-2;Q9HA65 Q9HA65-2 TBC1D17 TBC1 domain family member 17 1 QLTACPELPHNVQEILGLAPPAEPHS(0.658)PS(0.189)PT(0.066)AS(0.079)PLPLS(0.003)PT(0.004)R 73.37100000000001 1.3041e-07 1491500.0 2907.9 2055.3 2898.9 2635.5 2409.3 2825.3 2792.1 3041.7 3944.4 2954.0 True False 2866.4328127564504 2050.541079127256 2660.563632077603 2829.32346177027 2267.5897108660483 2704.4685050959783 2936.661276149776 3183.028486271778 3500.1401356266088 3464.5949640424187 0.8273500488530281 0.5918559313307801 0.7679291979843184 0.8166390273999224 0.6545035521902021 0.7806016383342137 0.8476203731253305 0.9187303333599162 1.0102595460517314 1.0 11.758470985502782 -7.658820436360671 1.3040651291763572 1.0077306769580456 0.7291861096584372 0.7210618222141929 0.06739874770946952 0.23749041503134075 0.7503905723584058 0.05248782318770833 0.02190310135509003 2.19371176116059e-08 7.658820436360671 -0.2785445672996084 QLVAGNS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 QLVAGNSPK 9 0 Q96EU6-2;Q96EU6 Q96EU6-2 RRP36 Ribosomal RNA processing protein 36 homolog 1 QLVAGNS(1)PK;QLVAGNS(1)PK;QLVAGNS(1)PK;QLVAGNS(1)PK 97.95700000000001 0.0046166 120619700.0 522069.0 426736.0 437757.0 445846.0 441821.0 423863.0 522922.0 424043.0 424185.0 447054.0 True False 688076.0822902091 564670.0667226933 431952.05615465785 343063.092952034 380481.780535594 397358.77960447443 569461.0449658565 358516.89788875764 446606.55310915905 431402.7755326473 1.594973702801635 1.3089161654685753 1.001273243134174 0.7952269025818356 0.8819641460716569 0.92108535721371 1.3200217459490158 0.8310491221251453 1.0352426512734876 1.0 18.71867593288767 -5.025856716612559 2.312960024070812 0.9660971299856653 1.6130289527772668 0.6819044270418446 0.13770613724686545 0.21990453541232727 1.9812308423740492 0.03853459993840808 0.23417318905988863 9.422003980704891e-06 5.025856716612559 0.6469318227916014 QLVAGNS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QLVAGNSPK 9 0 Q96EU6-2;Q96EU6 Q96EU6-2 RRP36 Ribosomal RNA processing protein 36 homolog 1 QLVAGNS(1)PK;QLVAGNS(1)PK;QLVAGNS(1)PK;QLVAGNS(1)PK 101.89 0.0033537 90182000.0 447495.0 482610.0 370740.0 477377.0 477821.0 395644.0 521694.0 508920.0 403600.0 361278.0 True False 523247.0650708734 530520.3313416236 379579.84763927874 450631.11436711607 384195.4051167494 374895.73214854416 472275.3675825224 495561.38924531196 409501.8864638166 426774.841524925 1.2260494625251102 1.243091859506061 0.8894147702872734 1.0558989671390875 0.9002297411533599 0.8784391573059703 1.1066148273759946 1.1611776070834052 0.9595267729480262 1.0 18.703115605901317 -5.245422028886326 24.648374715887194 0.99843806670854 1.2345707273556479 0.5391110605788417 0.08892726149881357 556.447224451109 856287.2856208092 0.02418028759566661 0.06350082905851387 5.683004122864858e-06 5.245422028886326 0.23613266064710792 QLVAGNS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 QLVAGNSPK 9 0 Q96EU6-2;Q96EU6 Q96EU6-2 RRP36 Ribosomal RNA processing protein 36 homolog 1 QLVAGNS(1)PK;QLVAGNS(1)PK;QLVAGNS(1)PK;QLVAGNS(1)PK 105.25 0.0026486 137464000.0 636630.0 530790.0 421716.0 483500.0 482985.0 405582.0 466313.0 405226.0 427954.0 409753.0 True False 627551.5394563563 529560.9883666408 387044.1383508367 519058.202908718 454576.77188504516 388236.20331782004 490456.40545296733 424054.2793102442 379753.3139645959 480578.26008844655 1.305825900948704 1.1019245611925503 0.8053717167305994 1.0800700864271089 0.9458954131661802 0.8078521971559186 1.0205547070787238 0.8823834004313895 0.7902007758209981 1.0 18.874411861206745 -4.95654881520439 3.277067696410207 0.9192417300374345 1.3038374174101424 0.62994206617237 0.0941573624115677 0.16246516129729133 3.3367419682981976 0.02384618410152748 0.1279591438408602 1.105226233687983e-05 4.95654881520439 0.3845956873727079 QLVAGNS(ph)PKK ddPTM_PC-9_AZD4547_30min_R2 1 QLVAGNSPKK 10 1 Q96EU6-2;Q96EU6 Q96EU6-2 RRP36 Ribosomal RNA processing protein 36 homolog 1 QLVAGNS(1)PKK 53.946999999999996 0.044325 84390000.0 225740.0 194660.0 212100.0 217440.0 212450.0 204280.0 213950.0 185370.0 206200.0 213750.0 True False 297520.62431631034 257580.03821622653 209287.41541632178 167312.56741451164 182954.98465393687 191506.33930680968 232991.13552393013 156725.32587883528 217099.31103435697 206266.6775604363 1.4424076047336174 1.2487719357420461 1.0146448175323928 0.811146858006131 0.8869827488268478 0.9284405099834808 1.1295626529673632 0.7598189282557025 1.0525176126461178 1.0 17.65415124669711 -5.122697710616612 2.1758052021086454 0.9325927304220655 1.4427326350801093 0.7185497318646578 0.10356584772372938 0.18742936379045197 1.538041541684239 0.027856766356211225 0.1393992003236663 7.538801171706029e-06 5.122697710616612 0.5101399046580438 QLVAGNS(ph)PKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLVAGNSPKK 10 1 Q96EU6-2;Q96EU6 Q96EU6-2 RRP36 Ribosomal RNA processing protein 36 homolog 1 QLVAGNS(1)PKK 57.434 0.037259 100890000.0 189500.0 155530.0 164310.0 217800.0 196000.0 163860.0 194460.0 202140.0 184130.0 128340.0 True False 221578.60720439372 170969.99053803823 168227.77354914483 205597.372117127 157595.20699777256 155266.89314095592 176039.34103151827 196834.03918503373 186822.55291026336 151607.0260611188 1.4615325751134158 1.127718120854857 1.1096304565813826 1.3561203425640875 1.0394980436740424 1.0241404846129074 1.1611555585857203 1.2983173953012053 1.2322816281281566 1.0 17.20997708961236 -4.758041226127956 24.986570978780097 1.157357750137254 1.4615330022134418 0.4109919565627784 0.11160637559234995 102.9107441576544 756580.710280655 0.02847160994744604 0.2013232651438311 1.745656435706793e-05 4.758041226127956 0.3041752520761878 QLVHELDEAEYR ddPTM_PC-9_AZD4547_30min_R2 2 QLVHELDEAEYR 12 0 H0YKK6;Q06323-3;Q06323;Q06323-2 H0YKK6 PSME1 Proteasome activator complex subunit 1 0 ; 162.31 1.4794e-12 2852000.0 20300.3 20578.2 24873.0 27132.0 23481.0 24775.0 20201.2 25460.0 21137.5 23119.0 False True 26755.37312752906 27229.700721366215 24543.167768270498 20877.13658522135 20221.068461563147 23225.815333494236 21999.06766509011 21525.742012597224 22254.785096938474 22309.610846875923 1.1992756534915394 1.2205367860631808 1.1001163550868187 0.9357911587303565 0.9063837375000542 1.0410677036415725 0.9860802958905356 0.9648640740683979 0.9975425053214173 1.0 14.445377727995742 -5.527910886785369 3.3845431005448416 0.9751719993899096 1.2064787587170756 0.8737662083178249 0.035885015681448 0.07772074338392682 1.8642641733300584 0.010577194814021026 0.02183728563806071 2.965439807948024e-06 5.527910886785369 0.23130675932716593 QLVHELDEAEYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLVHELDEAEYR 12 0 H0YKK6;Q06323-3;Q06323;Q06323-2 H0YKK6 PSME1 Proteasome activator complex subunit 1 0 130.69 0.00011639 2770300.0 13144.0 10533.0 13910.0 12569.0 10788.0 9888.7 9899.8 9717.4 8005.7 10040.0 False True 15369.019594166519 11578.64662982807 14241.667153968758 11864.799679247806 8674.168842305977 9370.119163938554 8962.019275654784 9462.328546436367 8122.768217203597 11860.172523403724 1.295851267242426 0.9762629175064598 1.2007976381343206 1.0003901423722927 0.7313695332162501 0.790049145191477 0.7556398743753514 0.7978238535539275 0.6848777453426506 1.0 13.533837375676931 -6.067952357421702 3.564128092599845 0.7819689803712048 1.137820953109487 0.696547393589816 0.10818897979093135 0.12588646157043373 3.1199963148515946 0.03042943434330883 0.04200382461975583 8.551605197808713e-07 6.067952357421702 0.3558519727382822 QLVHELDEAEYR ddPTM_PC-9_Lapatinib_30min_R1 4 QLVHELDEAEYR 12 0 H0YKK6;Q06323-3;Q06323;Q06323-2 H0YKK6 PSME1 Proteasome activator complex subunit 1 0 ;;; 177.16 7.1549e-05 9421200.0 38382.5 39637.2 47737.3 42373.4 50501.8 45581.0 44626.1 42205.5 50909.0 40806.2 False True 37835.158511511545 39545.42249870232 43812.52346530688 45489.68118951868 47531.38341435896 43631.60688450065 46936.62110081568 44166.521608752875 45175.092324463825 47859.49729915633 0.7905465089826278 0.8262816103461126 0.9154405277482762 0.9504838904841687 0.9931442262599119 0.9116603672573425 0.9807169684091747 0.9228371399866635 0.9439107151938299 1.0 15.546517622898426 -5.267666065776511 1.9778432507367618 0.955071606815212 0.7888121365274903 0.829804048703702 0.026880507953417794 0.14086997914887636 0.9901477294803681 0.007311431468025589 0.029099870765199907 5.399256182151828e-06 5.267666065776511 -0.1662594702877217 QLVTS(ph)PSPMSSSDGK ddPTM_PC-9_AZD4547_30min_R2 2 QLVTSPSPMSSSDGK 15 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 QLVT(0.039)S(0.717)PS(0.169)PMS(0.055)S(0.016)S(0.005)DGK;QLVT(0.037)S(0.923)PS(0.037)PMS(0.002)S(0.001)SDGK 144.4 9.3126e-05 14398900.0 65138.0 75784.0 99676.0 142901.0 135951.0 123154.0 104690.0 129322.0 95052.0 115743.0 True False 85850.5290454322 100279.69596310757 98354.23111285869 109957.38224844163 117076.55033507799 115453.16091144891 114007.20718859667 109338.25642392365 100076.25466749599 111690.87279942745 0.7686440878620503 0.8978325036745672 0.8805932718377224 0.9844795684057479 1.048219495475893 1.0336848304406907 1.0207387974604591 0.9789363596457108 0.8960110361677557 1.0 16.769151770329543 -5.129248274156409 1.1065071202274264 0.9989670506013679 0.7494113212083946 0.6937797744388454 0.04613789797172 0.6126183342153172 0.9209911798238355 0.016251998659790007 0.15567168064750397 7.425944957737022e-06 5.129248274156409 -0.24955572939297332 QLVTS(ph)PSPMSSSDGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLVTSPSPMSSSDGK 15 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 QLVT(0.039)S(0.937)PS(0.024)PMSSSDGK 145.94 0.00010062 5269300.0 24566.0 25707.0 22336.0 29009.0 34346.0 30878.0 33617.0 29106.0 29693.0 24811.0 True False 28724.538599383366 28259.02106835568 22868.574949751724 27383.719778446928 27616.14785482397 29258.703322387664 30432.55439399652 28341.998340356156 30127.203951362928 29309.037896232057 0.98005737005363 0.9641742990133645 0.7802567600723491 0.9343097468909873 0.9422399995727692 0.9982826261980143 1.0383334486018356 0.9670054145311873 1.0279151454246833 1.0 14.839057990186378 -6.616429659938124 2.400291918758675 1.0073912720352538 0.9095665360208167 0.40338696853854894 0.05321201343565278 0.3114345170875952 3.6499010091735484 0.020354326301534376 0.02057991722417078 2.4186350379607817e-07 6.616429659938124 -0.09782473601443709 QLVTS(ph)PSPMSSSDGK ddPTM_PC-9_Lapatinib_30min_R1 1 QLVTSPSPMSSSDGK 15 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 QLVT(0.026)S(0.682)PS(0.27)PMS(0.016)S(0.004)S(0.001)DGK 89.484 0.020361 0.0 38078.0 36844.0 34914.0 30665.0 36978.0 35154.0 33234.0 36539.0 33671.0 28431.0 True False 37535.00073735003 36758.689981688614 32043.505691937426 32920.20639544124 34803.026741545174 33650.545367976505 34954.6939047891 38236.73533217759 29878.617408651142 33345.26046807379 1.1256472497279688 1.1023662573241253 0.9609613253019054 0.9872529388984824 1.0437173455240247 1.0091552711125171 1.048265732944454 1.1466917575523845 0.8960379073139415 1.0 15.025194097927178 -5.110693098334623 6.308713009593183 1.0184365272006766 1.1199706375677014 0.3060079707390001 0.06141968465773416 0.2735958842650347 13.237783158183651 0.015403434214691383 0.04225660546551121 7.750092779728126e-06 5.110693098334623 0.10153411036702487 QLVTSPS(ph)PMSSSDGK ddPTM_PC-9_AZD4547_30min_R2 1 QLVTSPSPMSSSDGK 15 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 QLVT(0.025)S(0.096)PS(0.825)PMS(0.043)S(0.01)S(0.001)DGK 109.07 0.0036046 0.0 7135.8 8060.8 9982.4 14895.0 13296.0 10957.0 9875.7 14055.0 11820.0 11895.0 True False 9404.8359661395 10666.295962464586 9850.026853615715 11461.187875455993 11450.07990566602 10271.857057884821 10754.618168234081 11883.1227017696 12444.781068991742 11478.55967055622 0.81933938020673 0.9292364432991379 0.8581239403130104 0.9984865875511553 0.9975188729503011 0.8948733423613483 0.9369309806195346 1.0352451041615551 1.0841761881426628 1.0 13.486654003574262 -1.7351569623330194 0.2332831508387551 1.0353367630069688 9.384317066507303e-19 0.5366861956013314 0.053267671146457425 39.42445559569473 0.5674100422462358 0.08132053260184244 15.346559950557106 0.01840106831466843 1.7351569623330194 -1.0353367630069688 QLVTSPS(ph)PMSSSDGK ddPTM_PC-9_Lapatinib_30min_R1 1 QLVTSPSPMSSSDGK 15 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 QLVT(0.328)S(0.186)PS(0.409)PMS(0.048)S(0.011)S(0.019)DGK 81.676 0.0075528999999999995 11219000.0 35821.0 30850.0 32910.0 31067.0 35668.0 33458.0 32032.0 32821.0 34346.0 28670.0 True False 35310.185971233135 30778.568720418356 30204.266836273728 33351.7708164739 33570.07836598609 32027.079334407375 33690.46022622026 34345.983478951275 30477.591800586026 33625.57129962632 1.0500992133812619 0.9153322168465402 0.8982528970923206 0.9918573730476526 0.9983496805706066 0.9524620131811201 1.0019297494164705 1.0214245335166383 0.9063813824606967 1.0 15.03727115886588 QLVYVEQAGS(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QLVYVEQAGSSPK 13 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 QLVYVEQAGS(0.725)S(0.275)PK 178.68 0.00012085 8113000.0 32049.0 36268.0 29073.0 45144.0 43172.0 39831.0 43280.0 37545.0 35412.0 34095.0 True False 37474.262703396475 39868.44735313819 29766.210579966486 42614.72803882274 34712.7565127951 37742.19224153191 39180.205079934836 36559.483532215745 35929.8335070779 40276.1536041285 0.9304330068786704 0.9898772297127072 0.7390529610284162 1.0580634997492542 0.8618687090625475 0.937085318834 0.9727891462783248 0.9077203322729462 0.8920870115907721 1.0 15.297638291265164 QLVYVEQAGS(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 1 QLVYVEQAGSSPK 13 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 QLVY(0.013)VEQAGS(0.494)S(0.494)PK 71.34899999999999 0.026102999999999998 9839800.0 64336.0 52916.0 42712.0 46596.0 50564.0 32626.0 37044.0 29528.0 44140.0 40423.0 True False 63418.55684222256 52793.47625314934 39200.384233087934 50022.825279699304 47589.924932648864 31230.662034920642 38961.957062315945 30899.978677263745 39168.48838519382 47410.06168973819 1.3376602894391376 1.1135500434199261 0.8268368113423648 1.0551098964405405 1.0037937778711983 0.6587348955439232 0.8218077697787342 0.6517599339878518 0.8261640459681527 1.0 15.532905649842643 -1.5228788297875397 0.4851221546199514 0.7928189877017604 16.632334654847025 0.5995692481050541 0.12813233213875327 67.54846659256654 0.7470539517814238 0.07443362834421612 1081.9397067029058 0.029999994162449847 1.5228788297875397 15.839515667145264 QLVYVEQAGSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 QLVYVEQAGSSPK 13 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 QLVYVEQAGS(0.03)S(0.97)PK;QLVYVEQAGS(0.053)S(0.947)PK;QLVYVEQAGS(0.369)S(0.631)PK 157.35 4.303e-12 12155300.0 177310.0 149468.0 105474.0 143003.0 114515.0 102901.0 91698.0 84246.0 121754.0 85365.0 True False 174781.52688532864 149121.9160292862 96802.33486141403 153519.91766402326 107779.45284515248 98500.16410394688 96445.6737582401 88160.37671514368 108040.78239354066 100120.22650828767 1.7457164549149389 1.4894284724469966 0.9668609254834337 1.533355676650565 1.076500289741462 0.9838188300122684 0.9632985973144657 0.8805451185015648 1.0791104471242616 1.0 16.611373934479147 -1.5228787452863985 0.3974389663516115 0.9565390134722983 13.661418373223295 0.6780682581617119 0.16186226193452455 42.047058911581765 0.5599920708848747 0.11849041042950433 417.43139538997224 0.029999999999581323 1.5228787452863985 12.704879359750997 QLWDS(ph)PETAPAAR ddPTM_PC-9_Lapatinib_30min_R1 1 QLWDSPETAPAAR 13 0 Q9Y613 Q9Y613 FHOD1 FH1/FH2 domain-containing protein 1 1 QLWDS(0.991)PET(0.009)APAAR 120.21 0.00021615 4497900.0 23167.0 26789.0 18955.0 20303.0 25481.0 25611.0 19053.0 19543.0 22905.0 18578.0 True False 22836.634331692527 26726.971716411263 17396.59306841595 21796.150348822546 23982.25767757348 24515.677232156948 20039.471112955023 20451.039125229105 20325.197699657103 21789.182546371052 1.0480721010571332 1.2266165405485847 0.7984050356819522 1.0003197826461212 1.1006497204076011 1.1251306550846254 0.9196981607872462 0.9385868002026164 0.9328113919098001 1.0 14.411324452165791 -7.282518212950077 24.646067265765467 0.9426563124201494 1.0465260322326253 0.1853747081483843 0.10448490531244138 1276.6395817547639 1492681.8124227817 0.0454613408758001 0.030686050776523824 5.2177322224576825e-08 7.282518212950077 0.10386971981247595 QLWDSPET(ph)APAAR ddPTM_PC-9_AZD4547_30min_R2 1 QLWDSPETAPAAR 13 0 Q9Y613 Q9Y613 FHOD1 FH1/FH2 domain-containing protein 1 1 QLWDS(0.35)PET(0.65)APAAR 118.08 0.00060834 6354900.0 13249.0 15983.0 26109.0 29928.0 25990.0 20966.0 18862.0 30178.0 17288.0 16814.0 True False 17461.906403680365 21149.192185399897 25762.777600682453 23028.56198299073 22381.737120055648 19654.992705632296 20540.68145946426 25514.683521451643 18201.808385848504 16225.346977783296 1.0762115859580839 1.303466250327874 1.5878105803196918 1.4192955019404392 1.3794304153064982 1.2113758018577399 1.2659625392042324 1.572520054972498 1.1218131982491035 1.0 13.985961710025004 -6.741600834074035 24.620668828650665 1.272093578193957 1.3671786606524066 0.07608831228684731 0.18189701835368222 681.2076371575712 845411.8261848931 0.06103042846675949 0.06094483518861646 1.8130056850883253e-07 6.741600834074035 0.09508508245844949 QMDTVLSS(ph)SPDVLFDPINGLTPDEEALSNER ddPTM_PC-9_AZD4547_30min_R2 1 QMDTVLSSSPDVLFDPINGLTPDEEALSNER 31 0 O75113 O75113 N4BP1 NEDD4-binding protein 1 1 QMDT(0.004)VLS(0.127)S(0.434)S(0.434)PDVLFDPINGLTPDEEALSNER 52.722 0.0034445 1530100.0 1297.3 1310.6 2694.5 4121.4 3354.6 2716.3 2066.4 3761.3 4095.8 2524.9 True False 1709.814414483699 1734.225819820128 2658.769169444976 3171.2749049952527 2888.8716946109516 2546.4493315992077 2250.3055968527706 3180.077511075486 4312.295626258574 2436.504019519748 0.7017490637346518 0.7117680931065963 1.0912229769147017 1.301567688618192 1.185662601607515 1.0451242071421374 0.9235796776137974 1.3051804904070308 1.7698701055738695 1.0 11.250596887219578 -5.331529029448083 3.307507903512111 1.2101207706357404 0.694307652042861 0.4549312761083181 0.22052510407851908 0.22876530872351034 4.860639086358442 0.06243254504356593 0.15717115815775567 4.660912721268673e-06 5.331529029448083 -0.5158131185928794 QMEHVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QMEHVQR 7 0 A0A0C4DG98;Q8NI27;H0Y815 A0A0C4DG98 THOC2 THO complex subunit 2 0 ; 85.212 0.013188 374810.0 1503.6100000000001 829.84 1663.13 1229.74 1784.98 1703.21 1977.37 1904.02 2195.56 1930.7 False True 1758.141475348809 912.2210309784986 1702.7853266556492 1160.8416546708725 1435.225982586144 1613.890669270155 1790.0591986809332 1854.0414924759466 2227.665911408561 2280.720626587209 0.7708710373613934 0.3999705270099277 0.7465996960809873 0.5089802061412122 0.6292861851886551 0.7076231303634609 0.7848656156363681 0.8129191584724121 0.9767377404491503 1.0 11.15527402139468 -7.690452458845789 0.8316245192239412 1.006137222536907 0.5947965431202484 0.6628938880889867 0.10286461194691987 0.3441185809079601 0.4406883307676142 0.08542957438677294 0.039003599629675076 2.0396119187143662e-08 7.690452458845789 -0.41134067941665853 QMEQISQFLQAAER ddPTM_PC-9_AZD4547_30min_R2 1 QMEQISQFLQAAER 14 0 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 0 123.26 0.0012711999999999999 0.0 5235.4 4435.2 5996.3 9400.7 8578.9 8188.7 8397.7 9245.6 5363.4 7488.7 False True 6900.148296915098 5868.791664936846 5916.785144087178 7233.513854367181 7387.867817593121 7676.65929450592 9145.079031499477 7816.904962752115 5646.898374401885 7226.522892382879 0.9548365652018074 0.8121183247233396 0.8187596209407666 1.0009674032848732 1.0223267714795876 1.0622894867734396 1.2654881424562916 1.0816965612869682 0.7814129227147404 1.0 12.819085932866537 -5.8958212403636825 4.066968162776326 1.0497723067427858 0.8574900762893523 0.30203540701810094 0.1168130500364939 0.2622469892855955 7.974346082697326 0.035328493328894255 0.054279523212005104 1.2710971929398084e-06 5.8958212403636825 -0.1922822304534335 QMEQISQFLQAAER ddPTM_PC-9_Lapatinib_30min_R1 4 QMEQISQFLQAAER 14 0 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 0 ;;; 145.61 0.00014517 21174300.0 38654.6 34475.9 37445.7 35052.2 38322.8 41504.6 39456.0 35618.5 38432.600000000006 31310.1 False True 38103.378315614515 34396.073171743 34367.05909058207 37630.05571871138 36068.72824952367 39729.54500994814 41498.8386203093 37273.46554172711 34103.91587478029 36722.009066914194 1.037616930113579 0.9366609846718105 0.9358708840782384 1.0247275863949208 0.9822101014081195 1.0819000925998812 1.1300808336681922 1.0150170562239138 0.9287050665620374 1.0 15.164357370533866 -6.172839023607353 1.9691363905797397 1.034826770704268 0.969853465196288 0.11663679584940434 0.058600703831730806 0.623298811834671 4.756829216866788 0.02098460505992978 0.029251857649672287 6.716777721109436e-07 6.172839023607353 -0.06497330550797997 QMGPVT(ph)PT(ph)S(ph)RR ddPTM_PC-9_Lapatinib_30min_R1 2 QMGPVTPTSRR 11 1 M0R2L7 M0R2L7 ITPKC 3 QMGPVT(1)PT(1)S(1)RR;QMGPVT(1)PT(1)S(1)RR 52.265 0.027108999999999998 16691000.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 QMGVTEWS(ph)VNGSPIDTLR ddPTM_PC-9_AZD4547_30min_R2 1 QMGVTEWSVNGSPIDTLR 18 0 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785;O95785-2 B9EGQ5 WIZ Protein Wiz 1 QMGVT(0.002)EWS(0.877)VNGS(0.12)PIDTLR 83.948 0.0017567999999999998 3011200.0 15269.0 16732.0 17986.0 20498.0 18444.0 20503.0 14145.0 17369.0 14737.0 20755.0 True False 20124.224385070225 22140.29178790659 17747.49388815637 15772.502790943057 15883.368966614324 19220.944168824703 15403.87759750409 14685.020149913626 15515.967733818217 20028.373767330344 1.0047857414113286 1.1054463055817911 0.8861175697202898 0.7875079112349436 0.7930433669319062 0.9596857134840027 0.7691027627330589 0.7332108098495431 0.7746993297642257 1.0 14.289757663752736 -5.412269412560884 4.178429792374166 0.8218168483535362 1.0531818907770558 0.5194157391593635 0.08439803069710723 0.1642652223563605 4.8041894674985315 0.022378605720511553 0.04913477347168744 3.870174859421256e-06 5.412269412560884 0.23136504242351963 QMGVTEWS(ph)VNGSPIDTLR ddPTM_PC-9_Lapatinib_30min_R1 1 QMGVTEWSVNGSPIDTLR 18 0 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785;O95785-2 B9EGQ5 WIZ Protein Wiz 1 QMGVT(0.001)EWS(0.496)VNGS(0.496)PIDT(0.006)LR 76.52600000000001 0.043327 0.0 5239.3 4892.1 7196.8 5852.2 6415.1 5178.2 4282.0 4061.9 7241.7 5429.7 True False 5164.586621230053 4880.772643019728 6605.1068844513775 6282.590310366906 6037.776430571862 4956.740456973769 4503.7010080130885 4250.630702694984 6426.063487518313 6368.216410379528 0.8109942075480219 0.7664269441384841 1.0371988730919608 0.9865541472690752 0.9481110630491321 0.7783561577610334 0.7072154458621297 0.6674758564685239 1.0090837172311702 1.0 12.636673648319452 -6.764440233977946 24.995840645059683 0.8038177938618359 0.91322420718457 0.06229996861482934 0.12773233882815832 164.77409358386862 1372485.8504461811 0.0452936718559117 0.0416720824883333 1.7201240421456303e-07 6.764440233977946 0.10940641332273404 QMGYTEAIEVIQAAS(ph)SPVK ddPTM_PC-9_AZD4547_30min_R2 1 QMGYTEAIEVIQAASSPVK 19 0 P19838;P19838-2;P19838-3 P19838 NFKB1 Nuclear factor NF-kappa-B p105 subunit;Nuclear factor NF-kappa-B p50 subunit 1 QMGYTEAIEVIQAAS(0.5)S(0.5)PVK 121.44 3.3767e-05 4558200.0 15657.0 12859.0 16400.0 15455.0 17056.0 19865.0 17700.0 17189.0 14319.0 15360.0 True False 20635.600314168874 17015.420278549547 16182.525284430367 11892.088527369748 14688.068807990348 18622.83840968166 19275.26571055654 14532.835013925118 15075.873107182117 14822.251075220129 1.3922042076771668 1.1479646507267687 1.0917724441656738 0.8023132564021241 0.9909472409724521 1.2564109402258987 1.3004276889345756 0.980474216782169 1.0171108983834443 1.0 13.855476947870283 -4.7692178862727195 2.3484078259541823 1.0600286542273811 1.4779091638477453 0.365360957297436 0.13425554499945028 0.7667338076848529 4.991613324172938 0.03924383037366605 0.67528434831179 1.7013047467903758e-05 4.7692178862727195 0.41788050962036416 QMGYTEAIEVIQAAS(ph)SPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QMGYTEAIEVIQAASSPVK 19 0 P19838;P19838-2;P19838-3 P19838 NFKB1 Nuclear factor NF-kappa-B p105 subunit;Nuclear factor NF-kappa-B p50 subunit 1 QMGYTEAIEVIQAAS(0.627)S(0.373)PVK 148.38 3.0099e-14 0.0 14210.0 12192.0 11934.0 12512.0 14623.0 8667.6 11556.0 12068.0 10398.0 9931.6 True False 16615.472339706805 13402.341185879028 12218.551819947032 11810.993204451317 11757.728122083818 8213.05579756225 10461.332021805147 11751.227787102942 10550.051078916646 11732.120461497656 1.4162377887471647 1.1423630732281247 1.0414615039153188 1.0067228037090572 1.0021826966975151 0.7000487102494188 0.8916829703664424 1.001628633601913 0.8992450353318215 1.0 13.518176168944228 -3.8625473877211483 0.6997049481158635 0.9067413388549668 2.8632563450702233 0.760459570456443 0.08563128052133688 4.673578758885158 0.6681817915137612 0.036447198435157216 9.745475028993882 0.00013723112141149108 3.8625473877211483 1.9565150062152565 QMGYTEAIEVIQAAS(ph)SPVK ddPTM_PC-9_Lapatinib_30min_R1 3 QMGYTEAIEVIQAASSPVK 19 0 P19838;P19838-2;P19838-3 P19838 NFKB1 Nuclear factor NF-kappa-B p105 subunit;Nuclear factor NF-kappa-B p50 subunit 1 QMGYTEAIEVIQAAS(0.734)S(0.266)PVK;QMGYTEAIEVIQAAS(0.651)S(0.349)PVK;QMGYTEAIEVIQAAS(0.636)S(0.364)PVK 235.79 3.2259999999999996e-118 0.0 27626.4 34342.2 32125.800000000003 32867.8 37214.2 35666.0 33749.7 31974.1 31262.1 28236.0 True False 27232.442469938727 34262.68274587849 29484.540733174214 35285.00765576664 35025.33392193223 34140.648321506786 35497.09432744961 33459.733413190814 27741.033093492697 33116.55497789498 0.8223211166776301 1.0346089068971256 0.8903263262997886 1.065479415939221 1.0576382098111154 1.0309239093346327 1.07188366516818 1.010362745627524 0.8376787112068149 1.0 15.015264980683448 -4.755461987522924 24.858804620411824 1.0038537520626072 0.8223207978191234 0.34517677725664153 0.07318270335327817 212.90201347410456 885323.5052890867 0.018378417930365543 0.162321001738149 1.7560545895979995e-05 4.755461987522924 -0.1815329542434838 QMGYTEAIEVIQAASS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 1 QMGYTEAIEVIQAASSPVK 19 0 P19838;P19838-2;P19838-3 P19838 NFKB1 Nuclear factor NF-kappa-B p105 subunit;Nuclear factor NF-kappa-B p50 subunit 1 QMGYTEAIEVIQAAS(0.314)S(0.686)PVK 230.05 1.3817999999999998e-35 3688000.0 25765.0 20382.0 28358.0 26696.0 30020.0 33391.0 30358.0 35908.0 31883.0 30591.0 True False 33957.73405470786 26970.082908266322 27981.95439121196 20541.649649088482 25852.241182919213 31303.05549145129 33059.80318876134 30359.24368375257 33568.27028956544 29520.018401175745 1.1503290273476037 0.9136201252229619 0.9478975931159133 0.6958549066578609 0.8757528817085545 1.0604009477922456 1.1199113340472922 1.0284290230165778 1.1371358185951692 1.0 14.84940600024575 -6.792737024023335 8.138227372493946 1.0746335175499475 0.9059934162038054 0.3228811903035549 0.10974123881192202 0.2675103065297456 59.242246214344846 0.04012413842180116 0.03583714578972977 1.6116212160130322e-07 6.792737024023335 -0.16864010134614216 QMGYTEAIEVIQAASS(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QMGYTEAIEVIQAASSPVK 19 0 P19838;P19838-2;P19838-3 P19838 NFKB1 Nuclear factor NF-kappa-B p105 subunit;Nuclear factor NF-kappa-B p50 subunit 1 QMGYTEAIEVIQAAS(0.322)S(0.678)PVK 127.49 2.8901e-05 2995500.0 23597.0 21256.0 25994.0 23379.0 26384.0 19689.0 26674.0 25331.0 22610.0 20791.0 True False 27591.506038005737 23366.155203989885 26613.795542793974 22069.150425740656 21214.244599128753 18656.474179496432 24147.245616963526 24666.088090413035 22940.62847608245 24560.24371853456 1.1234215081173489 0.9513812432714768 1.0836128439030794 0.8985721265089083 0.8637636027658503 0.7596208894872323 0.9831842832545118 1.0043095814964818 0.9340554083659253 1.0 14.584037256616524 -5.768375072997914 24.992767922179013 0.9142248214616142 1.0426628076946372 0.3616731554653092 0.07990383809446959 184.2057356290333 663787.4572084752 0.023658478649573485 0.03597041400124007 1.7046095883589713e-06 5.768375072997914 0.12843798623302294 QMGYTEAIEVIQAASS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 1 QMGYTEAIEVIQAASSPVK 19 0 P19838;P19838-2;P19838-3 P19838 NFKB1 Nuclear factor NF-kappa-B p105 subunit;Nuclear factor NF-kappa-B p50 subunit 1 QMGYTEAIEVIQAAS(0.131)S(0.869)PVK 221.13 2.3375e-28 2661000.0 24656.0 28812.0 28063.0 28887.0 27832.0 26545.0 25432.0 26902.0 29540.0 28999.0 True False 24304.400918643376 28745.28758420401 25755.76846631266 31011.4463442071 26194.97647981733 25409.732229417303 26748.744520268305 28151.9651305794 26212.89413000964 34011.438511261375 0.7145949122556535 0.8451652985711346 0.7572678367539434 0.9117946109200596 0.7701813750436939 0.7470937232191458 0.78646319271123 0.8277205070658252 0.7707081875213955 1.0 15.053732405565048 -11.731753504928745 2.2363304482307678 1.6002933900965308 0.7952545694755063 0.5743833965413312 0.05357575882927655 10046252.652628373 1593559.9993403514 30595060.40978921 0.01306504168063801 1.854583941857748e-12 11.731753504928745 -0.8050388206210245 QMIQQY(ph)EMY(ph)CK ddPTM_PC-9_Lapatinib_30min_R1 1 QMIQQYEMYCK 11 0 H0YJG4;Q9HCK8-2;Q9HCK8;A0A2R8Y840;A0A2R8Y4P3 H0YJG4 CHD8 Chromodomain-helicase-DNA-binding protein 8 2 QMIQQY(1)EMY(1)CK 43.083 0.0456 14795000.0 10104.0 12124.0 21138.0 14227.0 20903.0 18332.0 22287.0 20482.0 24476.0 19785.0 True False 9959.915107153338 12095.927622896334 19400.115235039622 15273.301039880722 19673.526636879185 17547.983093979197 23440.91180887149 21433.668493217137 21719.2551362937 23204.81088814464 0.4292176805561414 0.5212680974304408 0.8360384977302772 0.6581954541023157 0.8478210286527441 0.7562217670536794 1.0101746539484826 0.9236734829055478 0.9359806999069357 1.0 14.502136319598057 -4.662395599116248 0.3819766123222043 0.9833829008463364 3.704313539016943e-15 0.8208992072963036 0.08008251539377224 2.6991624849302966 0.291731091119138 0.06917093662781992 1.2481987073703915 2.175726998346336e-05 4.662395599116248 -0.9833829008463327 down QMLDPANY(ph)GT(ph)GMERWPR ddPTM_PC-9_Lapatinib_30min_R1 1 QMLDPANYGTGMERWPR 17 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 2 QMLDPANY(1)GT(1)GMERWPR 64.407 0.036563 0.0 12620.0 13519.0 14906.0 11432.0 10207.0 12599.0 11812.0 11607.0 14166.0 10721.0 True False 12440.03648577544 13487.697586104878 13680.48621882395 12272.74741603405 9606.6443277341 12060.170139703474 12423.567563440125 12146.30359343674 12570.475905406798 12574.110565165467 0.9893372911988337 1.0726561943450978 1.0879883827905503 0.9760330444392389 0.7640018972274468 0.9591270950896693 0.9880275427080786 0.9659771584231256 0.9997109410053433 1.0 13.618168733567755 -5.93769174157015 6.766155639284464 0.9404444793549285 1.0502942468429335 0.31172284816295015 0.06865826222089735 0.2551245997314699 21.955144470170353 0.02050466772381343 0.03054088587998092 1.154272259494229e-06 5.93769174157015 0.10984976748800501 QMMS(ph)PVS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 QMMSPVSK 8 0 Q8IY63-2;Q8IY63 Q8IY63-2 AMOTL1 Angiomotin-like protein 1 2 QMMS(1)PVS(1)K 54.538999999999994 0.036732 3912300.0 20625.0 16223.0 23394.0 44524.0 23862.0 26028.0 18816.0 35808.0 30020.0 27758.0 True False 27183.320973349488 21466.76749194411 23083.780274631932 34259.67968894275 20549.17318810186 24400.465045416247 20490.58754857806 30274.696385981173 31606.795912955335 26786.20086887764 1.0148255479161008 0.8014114281090875 0.8617788087093949 1.279004807611534 0.7671551963898524 0.9109341472073655 0.7649680389123666 1.130234800156253 1.1799656124313862 1.0 14.709202355418046 -7.790636081187324 24.997965670615685 1.1163254035221477 0.9161737618173977 0.25282298105292644 0.14845204467445 295.0002799490707 252572.66865655401 0.08110535044888682 0.03897140048495844 1.619436482576414e-08 7.790636081187324 -0.20015164170474997 QMNMS(ph)PPPGNAGPVIMSIEEK ddPTM_PC-9_AZD4547_30min_R2 4 QMNMSPPPGNAGPVIMSIEEK 21 0 Q86U42-2;Q86U42;B4DEH8;G3V4T2;Q92843-2 Q86U42-2 PABPN1 Polyadenylate-binding protein 2 1 QMNMS(0.999)PPPGNAGPVIMS(0.001)IEEK;QMNMS(0.979)PPPGNAGPVIMS(0.021)IEEK;QMNMS(1)PPPGNAGPVIMSIEEK;QMNMS(1)PPPGNAGPVIMSIEEK 81.22399999999999 0.00040907 17972700.0 184158.0 185760.0 241566.0 326735.0 285186.0 253151.0 228743.0 268829.0 214706.0 247092.0 True False 242716.4132756405 245803.287265212 238362.67700357977 251411.29375542857 245592.84656868692 237321.42795113643 249100.68386609238 227287.65512586362 226054.92082901348 238441.3842889511 1.0179290562308965 1.0308751058387562 0.9996699092919374 1.0543945402143786 1.0299925380028385 0.9953030119282588 1.0447040668251781 0.9532223435275353 0.9480523756525113 1.0 17.863275128554413 -7.767612864777842 24.998529883101984 0.9629780035299291 1.024186146881561 0.601850275612376 0.021389250218187356 93.5596304597281 378846.78853967844 0.010896412217579476 0.005442408670137776 1.707603889002745e-08 7.767612864777842 0.06120814335163183 QMNMS(ph)PPPGNAGPVIMSIEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QMNMSPPPGNAGPVIMSIEEK 21 0 Q86U42-2;Q86U42;B4DEH8;G3V4T2;Q92843-2 Q86U42-2 PABPN1 Polyadenylate-binding protein 2 1 QMNMS(1)PPPGNAGPVIMSIEEK;QMNMS(1)PPPGNAGPVIMSIEEK 101.73 8.4279e-05 20555800.0 181976.0 152496.0 170312.0 196255.0 216506.0 187764.0 205562.0 194067.0 176428.0 158215.0 True False 212780.94261016778 167634.7950690456 174372.8839918565 185259.46861729477 174083.20350132525 177917.32530036912 186089.67921999932 188972.94688098287 179007.9257310162 186898.12707074874 1.1384862221204672 0.8969313801929584 0.9329835816163587 0.9912323441698606 0.9314336437166515 0.9519481446329314 0.9956743929785696 1.0111013408360627 0.9577834114049427 1.0 17.51189258616685 -7.28125693836294 22.73261230002601 0.9920649043178336 0.9673466760638421 0.011679802335851641 0.06256106447735069 1126.1739357610816 1291816.6863323976 0.025413729583398565 0.017169659739885657 5.2329075443209724e-08 7.28125693836294 -0.024718228253991503 QMNMS(ph)PPPGNAGPVIMSIEEK ddPTM_PC-9_Lapatinib_30min_R1 4 QMNMSPPPGNAGPVIMSIEEK 21 0 Q86U42-2;Q86U42;B4DEH8;G3V4T2;Q92843-2 Q86U42-2 PABPN1 Polyadenylate-binding protein 2 1 QMNMS(1)PPPGNAGPVIMSIEEK;QMNMS(1)PPPGNAGPVIMSIEEK;QMNMS(1)PPPGNAGPVIMSIEEK;QMNMS(1)PPPGNAGPVIMSIEEK 114.24 1.9725e-06 10800600.0 194996.6 170291.5 193662.0 168521.3 195425.3 191728.4 171346.7 167446.8 206117.4 171336.2 True False 192215.91272600336 169897.20049442843 177739.8579169386 180914.9185725767 183930.76807492232 183528.62327272966 180218.19372015807 175226.9896225969 182902.28789955468 200951.433878864 0.9565291922319573 0.8454639870688585 0.8844916131530686 0.90029175249197 0.9152996051065655 0.9132984011617602 0.8968246219571433 0.8719867593889672 0.9101815516768615 1.0 17.616487346148205 -8.563564684660667 20.144245033437922 1.0000000007365757 0.8965748751112664 0.5483096581266824 0.02757098667194479 1050.9908325867282 520362.0861911168 0.02581158515793044 0.00666452265120058 2.7317145467256706e-09 8.563564684660667 -0.10342512562530926 QMPS(ph)ESLDPAFSPR ddPTM_PC-9_Lapatinib_30min_R1 1 QMPSESLDPAFSPR 14 0 Q15018 Q15018 FAM175B BRISC complex subunit Abro1 1 QMPS(0.513)ES(0.159)LDPAFS(0.328)PR 78.513 0.013863 2202500.0 18647.0 14104.0 17714.0 16555.0 18194.0 16918.0 17986.0 14720.0 18839.0 13541.0 True False 18381.09036055901 14071.343054547178 16257.623298017417 17772.509925861064 17123.86469078027 16194.456577784205 18917.22707382611 15403.944938001972 16717.153436535267 15881.543807751648 1.1573868751718805 0.8860185901876286 1.0236802854192428 1.1190668955738705 1.0782241889118018 1.0197029189240296 1.1911453510327359 0.9699274279924497 1.0526151386098728 1.0 13.955063539859747 -4.462695143027848 22.97428292159025 1.0431263027512128 3.915252972953226 0.16944265819263582 0.07862957523336714 883.7587602129735 362326.8265107151 0.018932155097469358 9540.303457423359 3.4459173519604606e-05 4.462695143027848 2.8721266702020136 QMPSESLDPAFS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QMPSESLDPAFSPR 14 0 Q15018 Q15018 FAM175B BRISC complex subunit Abro1 1 QMPS(0.003)ES(0.005)LDPAFS(0.992)PR;QMPSESLDPAFS(1)PR 132.15 1.2448e-05 7055300.0 25613.0 25104.0 32614.0 32538.0 39539.0 31524.0 37648.0 29817.0 30680.0 25379.0 True False 29948.77502019075 27596.159213443843 33391.64144928376 30715.00134961929 31791.61678308639 29870.825945169654 34081.70889208382 29034.335343722923 31128.636959142375 29980.011799946526 0.9989580798044972 0.9204852685712774 1.1137968080900928 1.0245159860035171 1.0604270937326012 0.9963580449699134 1.1368143921859502 0.9684564348228413 1.0383130322583094 1.0 14.871713330671145 -5.247538916983899 24.982810443553902 1.0429506209244115 0.9597216764263502 0.2868557291585936 0.052096414948787265 935.6216049017099 1681553.6346086587 0.012447065845531615 0.0326150949801143 5.65537077229324e-06 5.247538916983899 -0.08322894449806129 QMQVLHPAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QMQVLHPAAR 10 0 P50991 P50991 CCT4 T-complex protein 1 subunit delta 0 ; 79.97399999999999 0.012258 0.0 12704.400000000001 16846.7 23288.9 15880.6 19382.6 19447.2 17066.1 20217.9 17207.3 13902.7 False True 14855.003996662292 18519.1290400384 23844.195699645075 14990.861467599867 15584.718669158297 18427.354597160996 15449.475460135756 19687.201547635766 17458.924209486657 16423.149456287356 0.9045161548460047 1.1276234859415852 1.4518649886923292 0.9127884701713435 0.9489482337501302 1.122035371242777 0.9407133206244529 1.1987470247431022 1.0630679734088866 1.0 14.003443197850782 -14.522878706206196 0.1558997968636651 0.7316252166108237 1.1007319492136902 0.014990625008203029 0.15902978717978092 800.1655015257261 7.241544800438179 67.56988433820368 0.7506713600127599 3.000000269914619e-15 14.522878706206196 0.3691067326028665 QMREEAERTRDELER ddPTM_PC-9_AZD4547_30min_R2 1 QMREEAERTRDELER 15 3 A0A5K1VW66;P35240-4;P35240-6;P35240-5;P35240-3;P35240;P35240-2 A0A5K1VW66 NF2 Merlin 0 98.368 0.0012438 1632100.0 10787.0 9868.5 11200.0 16500.0 11880.0 12411.0 12882.0 12589.0 9920.6 11070.0 False True 14217.041616461624 13058.299635964391 11051.480682050003 12696.179922458805 10230.667063726856 11634.93820803217 14028.473044259285 10643.659316440944 10444.98266269369 10682.442669445756 1.3308792807403156 1.2224076496393594 1.0345462198135433 1.188509062517396 0.9577085859762129 1.0891645823020206 1.3132270846988905 0.9963694302693764 0.9777710010622144 1.0 13.382953953930679 -5.023807019779664 2.9218285934825112 1.0790785809116168 1.3293400885194895 0.4029409822597927 0.10386750438482845 0.2965744068236503 4.7406495799551545 0.027788459314893453 0.13365682228157066 9.466577184764588e-06 5.023807019779664 0.2502615076078727 QMS(ph)SPQSRNGKDS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QMSSPQSRNGKDSK 14 2 P20941;P20941-3 P20941 PDC Phosducin 2 QMS(0.866)S(0.134)PQS(0.005)RNGKDS(0.995)K 80.411 0.023306 0.0 24775.0 24029.0 24616.0 27345.0 32295.0 22896.0 23400.0 17567.0 23967.0 14187.0 True False 28968.918171445202 26414.44031787133 25202.938796699862 25812.948303686164 25967.0265815973 21695.293453895567 21183.382598670883 17105.88486377504 24317.47203389066 16758.99079576979 1.7285598234684496 1.5761354988355691 1.5038458522849385 1.540244792675805 1.549438560951519 1.2945465343516849 1.2640010879424717 1.0206989831447852 1.451010525050753 1.0 14.032647654017758 -6.8729546063578875 1.5167397873205246 1.1738317058262804 1.5899388172636315 0.683782589913113 0.12913277285099797 0.22896480394883126 1.0877977633583924 0.058226934076076424 0.048123827603341746 1.3398167214003473e-07 6.8729546063578875 0.41610711143735113 QMSSQNS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 1 QMSSQNSPSR 10 0 B5MCN7;Q15788-2;Q15788-3;Q15788 B5MCN7 NCOA1 Nuclear receptor coactivator 1 1 QMS(0.001)S(0.086)QNS(0.847)PS(0.066)R 76.24 0.020613 459840.0 3579.7 2363.8 4120.4 3592.7 4557.8 4566.3 3759.4 4259.4 3259.9 3936.3 True False 4717.970137614504 3127.8521233716015 4065.7608037784653 2764.458521661679 3925.0281433547357 4280.768539145699 4093.9793170771895 3601.2076012748066 3432.211658782246 3798.491335116474 1.242064209544876 0.8234459019177126 1.0703620056181584 0.7277780249502429 1.033312385648599 1.126965461147863 1.0777908795602544 0.9480626079049307 0.9035723280587669 1.0 11.891210814922875 -9.012630845794071 0.002344980222559116 6.016255985185961e-05 1.9696680483896671 0.003953504776772587 0.1425045844378447 949439.8959319452 944.4451310994123 398913.4614855551 394327.7805592177 9.713352601281508e-10 9.012630845794071 1.9696078858298154 QMSSQNS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QMSSQNSPSR 10 0 B5MCN7;Q15788-2;Q15788-3;Q15788 B5MCN7 NCOA1 Nuclear receptor coactivator 1 1 QMS(0.005)S(0.045)QNS(0.937)PS(0.013)R;QMS(0.001)S(0.003)QNS(0.941)PS(0.055)R 77.387 0.019229 3012250.0 11043.0 11987.099999999999 16813.9 11541.8 18428.7 14229.5 13770.8 10325.4 12753.5 11377.400000000001 True False 12912.361790808047 13177.10006801596 17214.807143070848 10895.150365020467 14817.728526529865 13483.279970396883 12466.330132041749 10054.369190665617 12939.995810248456 13440.032556551163 0.9607388774154486 0.9804366181831129 1.2808605240081596 0.8106491051399851 1.1025068923145698 1.0032178057354957 0.9275520784334115 0.7480911335861868 0.9627949750717701 1.0 13.714249012392166 -7.3037704917239 3.659134609942161 0.8841293596077585 1.0279462657956417 0.15465659544935983 0.1274954847571046 0.37824681827364875 10.647680709090805 0.054347924918525525 0.036498242540730724 4.968548211426964e-08 7.3037704917239 0.14381690618788323 QMWTSNLSK ddPTM_PC-9_AZD4547_30min_R2 1 QMWTSNLSK 9 0 Q8NEL0 Q8NEL0 CCDC54 Coiled-coil domain-containing protein 54 0 101.6 0.015878 4154100.0 9838.2 10229.0 13818.0 19800.0 16937.0 16729.0 14336.0 19108.0 14861.0 17110.0 False True 12966.542952727614 13535.324211002673 13634.764291479183 15235.415906950553 14585.589903900822 15682.932985429863 15611.876227488052 16155.297658158195 15646.522120667194 16510.984107878674 0.7853282922451769 0.8197769510627727 0.8257996132994264 0.9227442657206939 0.8833870718185055 0.9498484695377011 0.9455448642845227 0.9784575863318314 0.947643218504524 1.0 14.01113849163854 -4.972052502581565 0.34408411586756243 0.9930560986701951 0.6351368361620837 0.9099441627418481 0.020904753797910507 1.5061773243218615 0.15842448116358465 0.019772145826932576 0.22319052979669468 1.0664671864465734e-05 4.972052502581565 -0.35791926250811135 QMWTSNLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QMWTSNLSK 9 0 Q8NEL0 Q8NEL0 CCDC54 Coiled-coil domain-containing protein 54 0 ; 131.03 0.005744399999999999 8921900.0 64993.0 64755.0 66230.0 76794.0 72920.0 61347.0 60718.0 61538.0 50115.0 49413.0 False True 75995.03122973727 71183.44844911387 67809.17437867365 72491.4811495073 58631.84946059987 58129.85532477862 54966.35147974775 59922.6927049006 50847.83706673473 58371.185746907235 1.301927145342663 1.2194963583189757 1.161689170966798 1.2419052349531585 1.0044656230699656 0.9958655898618368 0.941669263291608 1.0265800144050623 0.871111943608733 1.0 15.832968754841856 -6.3174459323482735 3.963730347500578 0.9700506985237801 1.2268509020387441 0.8601465254149947 0.051041084813552996 0.08124297345596333 2.631832116402214 0.015953778529745773 0.01871355873949386 4.814531889616123e-07 6.3174459323482735 0.256800203514964 QMWTSNLSK ddPTM_PC-9_Lapatinib_30min_R1 2 QMWTSNLSK 9 0 Q8NEL0 Q8NEL0 CCDC54 Coiled-coil domain-containing protein 54 0 ; 135.77 0.0047908000000000004 8763500.0 31036.2 41148.0 44915.0 37292.0 36475.0 40507.0 35218.0 28243.0 44465.0 32026.0 False True 30593.618096657967 41052.72433412556 41222.262076913845 40034.57808246519 34329.612212609136 38774.61003642897 37041.41571700256 29555.272886140592 39456.8834627921 37561.651428037425 0.8144907620813963 1.0929424765249343 1.0974560624920768 1.0658364731158194 0.9139537508988284 1.0322924728353702 0.9861498179324846 0.7868470038588193 1.050456568406894 1.0 15.196972873176515 -7.538233019448409 24.98999214247931 0.9284907659722219 1.0099811508913783 0.047895985777822725 0.10278228949842536 547.9569338079441 891821.417827972 0.047200954075743845 0.02726170488184843 2.8957894433507485e-08 7.538233019448409 0.08149038491915639 QNALY(ph)EIEMRK ddPTM_PC-9_Lapatinib_30min_R1 1 QNALYEIEMRK 11 1 C9J9F8;Q0VFZ6 C9J9F8 CCDC173 Coiled-coil domain-containing protein 173 1 QNALY(1)EIEMRK 67.563 0.034614 0.0 4108.1 5191.2 6443.1 6694.0 6929.4 5459.7 4841.8 5328.5 6047.1 5492.8 True False 4049.517740666727 5179.180095346378 5913.373189085244 7186.29909052939 6521.826315724571 5226.201358182316 5092.484712890654 5576.081562645619 5366.011919213995 6442.22316130406 0.6285901061283645 0.803942981431582 0.9179087779207319 1.1154998686935755 1.0123564726690402 0.811241900090342 0.7904856111597061 0.8655523757914785 0.8329441226819881 1.0 12.653342921807887 -4.883053093662668 2.556706018965459 0.9145408552624684 0.6009332517927894 0.4637493821108728 0.09629685968543236 0.4102142695646575 4.116996761053971 0.028642803376701245 0.2568143338648644 1.3090218817886304e-05 4.883053093662668 -0.313607603469679 QNAPPKGTDTQTPAVLS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 3 QNAPPKGTDTQTPAVLSPSK 20 1 P46087-2;P46087;P46087-4 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 QNAPPKGTDTQT(0.001)PAVLS(0.922)PS(0.077)K;QNAPPKGTDTQTPAVLS(0.974)PS(0.026)K;QNAPPKGTDTQTPAVLS(0.828)PS(0.172)K 107.75 5.1655e-05 38262000.0 98909.0 37054.3 121096.0 257228.0 196514.0 107123.0 76370.0 91046.0 71178.0 168437.0 True False 130360.00456499522 49031.37783867009 119490.18791727933 197928.05873298354 169231.42317855367 100424.58187567741 83166.7820517063 76976.93272894458 74940.32376723304 162540.07189823233 0.8020176381281208 0.30165716838964507 0.7351429498080517 1.2177185380901512 1.041167394613378 0.6178450686213186 0.5116694060759226 0.4735874165057615 0.46105752810392375 1.0 17.31043591197468 -6.975855012254114 24.046674368923348 0.5672888427466563 0.8103322463958076 0.12436270308336028 0.2634613579203009 302.00612279665256 300774.5563766914 0.10058991811501415 0.08870684736431991 1.0571703830691376e-07 6.975855012254114 0.24304340364915133 QNAPPKGTDTQTPAVLS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QNAPPKGTDTQTPAVLSPSK 20 1 P46087-2;P46087;P46087-4 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 QNAPPKGTDTQTPAVLS(0.966)PS(0.034)K;QNAPPKGTDTQTPAVLS(0.993)PS(0.007)K 129.26 1.4444000000000001e-05 14954000.0 49025.2 8403.8 23367.0 63204.9 72786.0 94022.0 65137.0 136125.0 93997.0 54117.0 True False 57324.19806816287 9238.073725220653 23924.157899840982 59663.73436605053 58524.105798672856 89091.32080372867 58966.751808958295 132551.8629863594 95371.52830014682 63927.98371006373 0.8966996101136023 0.1445075096865032 0.37423607802720005 0.9332960450723254 0.915469289069097 1.3936200648496857 0.9223934243944499 2.0734560249472205 1.491858850619954 1.0 15.964159971477178 -6.439713056701209 1.0263552235053612 1.4817730463867087 0.4381339732437196 0.5329593145421635 0.355027302241411 0.37525200746807647 0.8442712123853032 0.17059065123243716 0.21666281664563572 3.633180238327141e-07 6.439713056701209 -1.0436390731429892 QNAPPKGTDTQTPAVLS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 4 QNAPPKGTDTQTPAVLSPSK 20 1 P46087-2;P46087;P46087-4 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 QNAPPKGTDTQTPAVLS(0.986)PS(0.014)K;QNAPPKGTDTQTPAVLS(0.961)PS(0.039)K;QNAPPKGTDTQTPAVLS(0.983)PS(0.017)K;QNAPPKGTDTQT(0.002)PAVLS(0.982)PS(0.016)K 160.15 3.8175e-06 46528900.0 482639.0 105658.0 147959.0 142389.0 95117.0 98415.5 46995.7 44036.2 136828.0 64165.9 True False 475756.47935484693 105413.35539260821 135794.38215825675 152860.76205577934 89522.40506721703 94206.49848273567 49428.90739427384 46082.28261405176 121416.98977728361 75256.89031931259 6.32176638359926 1.4007136747923372 1.804411284894785 2.0311862662301885 1.1895575898416253 1.251798979243236 0.6568024161581559 0.6123330690190107 1.613367085221236 1.0 16.199536056762916 -4.760978508715723 6.573726558190926 1.2797394049747821 6.459188687981624 0.924279451705165 0.4326735000880273 0.03274669507004503 6.853198397699073 0.12074714433279762 0.75829170605207 1.7338897980535232e-05 4.760978508715723 5.179449283006842 QNDTPKGPQPPTVS(ph)PIR ddPTM_PC-9_AZD4547_30min_R2 1 QNDTPKGPQPPTVSPIR 17 1 P46087-2;P46087;P46087-4 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 QNDTPKGPQPPT(0.408)VS(0.592)PIR 84.689 0.0015865 82231000.0 70751.0 35979.0 78604.0 169010.0 127000.0 68958.0 58370.0 78235.0 56265.0 83586.0 True False 93248.34628777955 47608.50814230763 77561.65960105871 130047.35567847028 109368.24217957171 64646.04535891409 63564.81692232682 66145.57841145103 59239.05303272595 80659.67958159828 1.156071370125468 0.5902392420756535 0.9615914668070867 1.612296953732746 1.355922100693827 0.8014666769599027 0.7880618575731178 0.8200575399575664 0.7344320401471166 1.0 16.29956005423748 -6.793392709487768 24.613429886783667 0.8150105745700914 1.121805096999577 0.2648407628355721 0.25425324103651215 266.2569207726647 205093.85565575704 0.10042325892429893 0.0885732307608527 1.609189871958571e-07 6.793392709487768 0.30679452242948557 QNDTPKGPQPPTVS(ph)PIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QNDTPKGPQPPTVSPIR 17 1 P46087-2;P46087;P46087-4 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 QNDTPKGPQPPT(0.064)VS(0.936)PIR;QNDTPKGPQPPT(0.428)VS(0.572)PIR;QNDTPKGPQPPT(0.044)VS(0.956)PIR 121.72 0.0003281 63068900.0 65929.0 41281.899999999994 46460.0 74580.0 75473.0 97109.0 75397.0 106280.0 86140.0 62671.0 True False 77089.47754289456 45380.09420942747 47567.782600531165 70401.52439162227 60684.60743746368 92016.4330893756 68254.85033299078 103490.26261296828 87399.63453913062 74032.75619663694 1.0412887686923167 0.6129731829636911 0.6425234591318918 0.9509510115310332 0.819699421648986 1.2429151340113904 0.9219547378690106 1.3978982808378744 1.180553568841746 1.0 16.175876119835642 -6.611583245107674 1.5153084555758098 1.1719077754227678 0.7691774880759318 0.4506775384714 0.17642764483640405 0.3272871360130568 1.5522813437735854 0.07215262000224716 0.07406008857673077 2.445776427275667e-07 6.611583245107674 -0.402730287346836 QNDTPKGPQPPTVS(ph)PIR ddPTM_PC-9_Lapatinib_30min_R1 4 QNDTPKGPQPPTVSPIR 17 1 P46087-2;P46087;P46087-4 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 QNDTPKGPQPPT(0.016)VS(0.984)PIR;QNDTPKGPQPPT(0.384)VS(0.616)PIR;QNDTPKGPQPPT(0.037)VS(0.963)PIR;QNDTPKGPQPPT(0.12)VS(0.88)PIR 123.63 0.00033324 90017000.0 479305.0 147814.0 166228.0 143548.0 116821.0 132041.0 71786.0 71300.0 170060.0 85997.4 True False 472470.02280622843 147471.74576466487 152561.37549863575 154104.99878209026 109949.81845892289 126393.91423260463 75502.72782840436 74612.85829344692 150906.05198880992 100861.93600566729 4.684324349868527 1.4621149623419745 1.5125763151132012 1.5278806345084563 1.0901022012183563 1.2531378956031811 0.7485750404807019 0.7397523907260171 1.4961645390222404 1.0 16.622022297081145 -3.2385337660982407 1.3514686264884002 1.1182294583665826 199.99999998224894 0.9250037496831818 0.2966918729117545 20.495516755154974 0.8680721430083903 0.08911166771695828 11978.061918105568 0.0005773859796047122 3.2385337660982407 198.88177052388235 up QNERMAMT(ph)LLTYELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QNERMAMTLLTYELR 15 1 Q9BX84-4;Q9BX84-3;Q9BX84-2;Q9BX84 Q9BX84-4 TRPM6 Transient receptor potential cation channel subfamily M member 6 1 QNERMAMT(0.996)LLT(0.004)YELR 88.101 0.012232999999999999 5881500.0 9238.4 9905.6 11473.0 11597.0 12413.0 10042.0 12036.0 11531.0 11966.0 8697.9 True False 10802.278653282712 10888.962504170224 11746.559831594792 10947.257687981286 9980.761757466076 9515.379842069331 10895.8629469061 11228.323468104409 12140.980112552088 10274.760417461486 1.0513411714130807 1.0597777526437433 1.1432441589228737 1.0654513821438523 0.9713863245418577 0.9260926245928204 1.0604493442386334 1.0928063538126287 1.1816314560404781 1.0 13.326817133692908 -10.075855114482243 7.033580696845555 0.9999999999961053 1.0581102837043448 0.06325704122443898 0.06983319102017879 0.0 0.0 0.07422810804817975 0.01800296058072974 8.397400865205272e-11 10.075855114482243 0.05811028370823945 QNGDDPLLTYR ddPTM_PC-9_Lapatinib_30min_R1 2 QNGDDPLLTYR 11 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ; 119.27 0.0045207 14604500.0 36635.0 39045.0 41340.0 36819.0 40302.0 36096.0 33649.0 34046.0 35960.0 36715.0 False True 36112.57818196381 38954.59370141764 37941.18477701475 39526.79208458344 37931.51559678061 34552.25822388574 35391.18057417851 35627.90145103364 31909.806124412557 43061.13883033763 0.8386350004408525 0.904634544267398 0.8811003565536045 0.917922590025321 0.8808758111631021 0.80240000990273 0.8218821316737808 0.8273794520718275 0.7410348864701022 1.0 15.394098854260227 -6.679956439122123 6.981984502216419 0.8268391579222966 0.8879554630447736 0.09942686025097658 0.0645359675665541 0.3859758455771367 27.465238426650483 0.020025463027321257 0.019956102482634682 2.0895057032568663e-07 6.679956439122123 0.06111630512247701 QNGSNDS(ph)DRYSDNEEDSKIELK ddPTM_PC-9_AZD4547_30min_R2 1 QNGSNDSDRYSDNEEDSKIELK 22 2 G5E972;P42167;H0YJH7;P42167-2;P42167-3 G5E972 TMPO Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 QNGS(0.034)NDS(0.754)DRY(0.079)S(0.134)DNEEDSKIELK 92.88600000000001 0.0005375 13874000.0 38449.0 40001.0 41154.0 38515.0 46176.0 30994.0 48982.0 40266.0 42261.0 35424.0 True False 50674.9822111183 52930.54098781092 40608.27107045411 29635.961800818233 39765.25945577872 29055.940280376184 53341.303109292705 34043.81492063001 44494.83018245855 34183.816542226436 1.48242611086216 1.548409345177333 1.1879384801954955 0.8669588360389675 1.1632773481175709 0.8499911133235837 1.5604256196320705 0.9959044473157792 1.3016343604434915 1.0 15.061025859043317 -5.327972531256577 4.688991050918943 1.1109224262116022 1.5165516335891172 0.39408092571936626 0.1996394647043802 0.19487374280948966 8.414571951950732 0.051169061452477245 0.11430206657981007 4.699238299335823e-06 5.327972531256577 0.40562920737751496 QNGSNDS(ph)DRYSDNEEDSKIELK ddPTM_PC-9_Lapatinib_30min_R1 1 QNGSNDSDRYSDNEEDSKIELK 22 2 G5E972;P42167;H0YJH7;P42167-2;P42167-3 G5E972 TMPO Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 QNGS(0.094)NDS(0.398)DRY(0.232)S(0.277)DNEEDSKIELK 81.807 0.0011140999999999998 16930000.0 109870.0 102940.0 37731.0 24836.0 38548.0 43664.0 35340.0 35136.0 55497.0 17511.0 True False 108303.2336523098 102701.64875461452 34628.90282587191 26662.522290467245 36280.682428283915 41796.59250575541 37169.73228005198 36768.54683027427 49246.34345068199 20537.753018059168 5.273373068469422 5.00062731615807 1.6861096145923158 1.298220027625343 1.766536115045387 2.035110290254392 1.8098246798161444 1.790290631986036 2.397844759715384 1.0 14.325990728341388 -5.251837367813088 6.724702092918164 1.7486900762646294 5.162439292121338 0.9345258835824516 0.36148062288673655 0.03052733328803378 7.788706464991004 0.09215385701156302 0.2263069758071531 5.599672556672451e-06 5.251837367813088 3.4137492158567087 QNGSNDSDRYS(ph)DNEEDSKIELK ddPTM_PC-9_AZD4547_30min_R2 2 QNGSNDSDRYSDNEEDSKIELK 22 2 G5E972;P42167;H0YJH7;P42167-2;P42167-3 G5E972 TMPO Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 QNGS(0.005)NDS(0.01)DRY(0.438)S(0.546)DNEEDSKIELK;QNGS(0.03)NDS(0.086)DRY(0.405)S(0.479)DNEEDSKIELK 88.95100000000001 0.00059248 21416700.0 35236.0 37003.0 32073.0 29294.0 38879.0 26994.0 39132.0 33592.0 38092.0 24658.0 True False 46440.315045669915 48963.496116896255 31647.691063874085 22540.720887788375 33481.32195039029 25306.060912708097 42614.672191271085 28401.128267367072 40105.465353640735 23794.730925311087 1.951705828968636 2.0577453164142523 1.3300293734445887 0.9472988351303948 1.4070897483768272 1.0635153216122049 1.7909289382188696 1.193588965410659 1.6854767334636882 1.0 14.538354519909834 -5.265373173362451 23.547124593494303 1.3091501499547433 2.004725661700324 0.5336797102553301 0.2625992866830306 100.81055945563116 603448.8195569908 0.0659879737049983 0.14641403764272173 5.427837368464383e-06 5.265373173362451 0.6955755117455806 QNGSNDSDRYS(ph)DNEEDSKIELK ddPTM_PC-9_Lapatinib_30min_R1 3 QNGSNDSDRYSDNEEDSKIELK 22 2 G5E972;P42167;H0YJH7;P42167-2;P42167-3 G5E972 TMPO Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 QNGS(0.001)NDS(0.024)DRY(0.433)S(0.542)DNEEDSKIELK;QNGS(0.001)NDS(0.005)DRY(0.195)S(0.799)DNEEDSKIELK;QNGS(0.023)NDS(0.066)DRY(0.332)S(0.579)DNEEDSKIELK 112.55 1.9861e-05 78342000.0 293950.0 293102.0 118323.0 107460.0 126553.0 117170.0 137216.0 114049.0 149590.0 67389.0 True False 289758.2190961724 292423.34032713296 108594.93967998863 115362.96687605164 119109.401352771 112158.91223661049 144320.37307695573 119348.1328963442 132741.59894746586 79037.09885980174 3.666103934434054 3.699823811167991 1.373974263309151 1.4596052808148456 1.5070062422717545 1.4190666643212848 1.825982673439916 1.5100267421005333 1.6794847086040783 1.0 16.27024237179856 -5.259671817592447 24.99404817348731 1.5016830848211618 3.6829641126211294 0.9496855042981287 0.2034801597892451 27.003576404371074 381833.894310873 0.050079820146672095 0.11921241087868513 5.499563012091983e-06 5.259671817592447 2.181281027799968 QNGSNDSDRYS(ph)DNEEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QNGSNDSDRYSDNEEGK 17 1 P42166 P42166 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin 1 QNGS(0.01)NDS(0.009)DRY(0.458)S(0.523)DNEEGK;QNGS(0.008)NDS(0.088)DRY(0.415)S(0.49)DNEEGK 53.188 0.029699 17414400.0 25033.0 37225.0 22232.8 28119.0 28523.0 19426.0 28663.0 21673.0 19534.5 17489.9 True False 29270.592475712936 40920.451988545494 22762.91427036353 26543.58359302801 22934.12290406872 18407.266362481467 25947.833137850554 21104.106714441663 19820.155106856815 20660.680420027784 1.4167293564707089 1.980595563971773 1.1017504655024772 1.2847390818405735 1.1100371545284218 0.8909322436756762 1.2559040946539968 1.0214623277355395 0.95931763639516 1.0 14.334600146939035 -5.280369776822267 24.298881323806913 1.0869822223034682 1.6986624009159024 0.6768400776202386 0.17145179774456637 264.7757611205429 339863.5826930616 0.04302187622072234 0.08981922812559295 5.24360806998793e-06 5.280369776822267 0.6116801786124342 QNGSNDSDRYS(ph)DNEEGK ddPTM_PC-9_Lapatinib_30min_R1 1 QNGSNDSDRYSDNEEGK 17 1 P42166 P42166 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin 1 QNGSNDSDRYS(0.999)DNEEGK 90.882 0.0010900999999999999 29452000.0 28266.0 36159.0 32674.0 38319.0 38810.0 28385.0 35011.0 43374.0 32538.0 36541.0 True False 27862.921656650426 36075.27605710233 29987.669845287408 41137.10708843676 36527.27210339575 27171.03971866678 36823.698269861314 45389.31438457182 28873.227799670065 42857.063162178085 0.6501360476151296 0.8417580066227971 0.6997135975418847 0.9598676169845626 0.8523046006482203 0.6339921057083906 0.859221224060885 1.059085971729124 0.6737099014556617 1.0 15.387245370335492 -14.522854801912741 0.027401311631941615 2.1595302168616195 5.061813543611752e-12 0.19452168856675978 0.1304949548488833 3013.813327867208 6.204367197790953 367.6454613173285 160.61524255767824 3.0001653994832405e-15 14.522854801912741 -2.1595302168565578 QNISLWPR ddPTM_PC-9_Lapatinib_30min_R1 1 QNISLWPR 8 0 Q9UJ71 Q9UJ71 CD207 C-type lectin domain family 4 member K 0 78.77 0.018206 0.0 5396.5 4760.7 6667.2 3961.9 6288.3 4529.9 3838.7 2983.8 6991.5 3259.5 False True 5319.544920403103 4749.676891646538 6119.048552136256 4253.27134251096 5918.434557273475 4336.166736712653 4037.449103096646 3122.4382408974357 6204.043646241114 3822.900231989255 1.391494571553353 1.242427634365711 1.6006299356005413 1.1125771232323685 1.548153024698163 1.134261025288729 1.0561220168164707 0.8167720974692211 1.6228630803197355 1.0 11.900451834640432 -6.883358658344299 8.354965955138308 1.1069742788535435 1.368549178011648 0.22921881043983017 0.2307722404455564 0.36598088858693023 25.225624776977213 0.0772049537470893 0.06811037564175496 1.308101192740771e-07 6.883358658344299 0.2615748991581046 QNLFQTGS(ph)NVSFSCGGETR ddPTM_PC-9_Lapatinib_30min_R1 1 QNLFQTGSNVSFSCGGETR 19 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 QNLFQT(0.002)GS(0.661)NVS(0.213)FS(0.114)CGGET(0.011)R 111.63 0.00012313 4327800.0 16350.0 16758.0 17950.0 15101.0 13765.0 15629.0 10435.0 10051.0 14198.0 10081.0 True False 16116.846001777205 16719.19788060846 16474.22028900376 16211.577915459262 12955.369763031244 14960.584102978457 10975.273241152869 10518.00615297947 12598.871728431852 11823.487417911854 1.3631211699317392 1.4140665346571017 1.393346963269596 1.3711333502922092 1.0957316826340642 1.2653275276729348 0.9282602377134522 0.8895857695120764 1.0655800004781448 1.0 13.529368010534336 -6.672133408478295 1.0115775785445933 0.9620349787153036 1.4045104668300996 0.8062447532481543 0.08557298548049617 0.2133949772763495 0.4706505297641483 0.046368725709483534 0.046243553203969806 2.1274854153210625e-07 6.672133408478295 0.442475488114796 QNLFQTGSNVS(ph)FSCGGETR ddPTM_PC-9_AZD4547_30min_R2 2 QNLFQTGSNVSFSCGGETR 19 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 QNLFQTGS(0.083)NVS(0.914)FS(0.003)CGGETR;QNLFQT(0.065)GS(0.162)NVS(0.751)FS(0.021)CGGETR 206.45 1.8222e-20 11188500.0 69600.0 45101.0 34825.8 37674.8 34026.8 35618.0 28186.5 33118.9 25955.2 27737.8 True False 91731.35223006658 59679.01625187519 34363.98713722653 28989.45692985764 29302.76616532162 33390.80082940051 30695.04389551425 28001.135001610615 27327.138883409 26766.70806472925 3.4270688800518534 2.229598653205876 1.2838331502747733 1.083041547722386 1.09474673144189 1.2474750630018598 1.1467620082860097 1.0461179960530143 1.0209376071694911 1.0 14.708152097880973 -4.866070266758038 1.56804646795256 1.0933920023766714 4.0798728908498205 0.990811670277792 0.07100514062669994 0.08207230371700706 0.21994491292121474 0.022788791709807927 0.36212795946981735 1.3612244250842038e-05 4.866070266758038 2.986480888473149 up QNLFQTGSNVS(ph)FSCGGETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QNLFQTGSNVSFSCGGETR 19 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 QNLFQTGS(0.06)NVS(0.85)FS(0.088)CGGET(0.002)R 93.26899999999999 0.00082868 3938500.0 35713.0 28867.0 23414.0 19558.0 24200.0 16145.0 15891.0 15832.0 12425.0 12169.0 True False 41758.50553609779 31732.724984643195 23972.278558089467 18462.228667891526 19458.18372115357 15298.327778351862 14385.689439123029 15416.42677539059 12606.69211920939 14375.143370249003 2.904910543189557 2.207471895572025 1.667620137111316 1.2843161415768007 1.3535992803678396 1.0642208835296554 1.0007336322569034 1.0724363839943776 0.876978531240278 1.0 13.811288724372778 -3.185745007504893 0.4880614376681496 0.9567060605734542 11.759623617535249 0.9853105425044194 0.07469550028102911 2.0163265107008272 0.1074548586439553 0.04286856367182652 17.52016646355132 0.000652011104747742 3.185745007504893 10.802917556961795 up QNLLAPQNAVS(ph)SEETNDFKQETLPSK ddPTM_PC-9_AZD4547_30min_R2 1 QNLLAPQNAVSSEETNDFKQETLPSK 26 1 P10451-4;P10451 P10451-4 SPP1 Osteopontin 1 QNLLAPQNAVS(0.367)S(0.367)EET(0.264)NDFKQET(0.002)LPS(0.001)K 65.67699999999999 0.00022424 8944800.0 23604.0 22901.0 21205.0 25018.0 33897.0 30983.0 32529.0 29667.0 27230.0 32920.0 True False 31109.581006300185 30303.300396536506 20923.807844899125 19250.486624246918 29190.986654810553 29045.628112115104 35424.01798297704 25082.6468298398 28669.322208853217 31767.48082006815 0.9792901483912329 0.9539094575416666 0.6586549296562773 0.6059809001942011 0.9188952318929244 0.9143195293523685 1.1151031516669394 0.7895699055240978 0.9024738968518471 1.0 14.955263067570753 -6.491239376601361 24.87367646975332 0.9390160111609157 0.7956841601392366 0.21691267457481123 0.1313452889407705 1078.7433776480766 848068.0581159871 0.04409102456512653 0.04994248804714115 3.2267151145259077e-07 6.491239376601361 -0.1433318510216791 QNLLAPQNAVS(ph)SEETNDFKQETLPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QNLLAPQNAVSSEETNDFKQETLPSK 26 1 P10451-4;P10451 P10451-4 SPP1 Osteopontin 1 QNLLAPQNAVS(0.331)S(0.331)EET(0.331)NDFKQET(0.005)LPS(0.001)K;QNLLAPQNAVS(0.481)S(0.481)EET(0.037)NDFKQETLPSK;QNLLAPQNAVS(0.498)S(0.498)EET(0.005)NDFKQETLPSK 77.641 0.00015024 11969500.0 58758.0 56815.0 54217.0 65392.0 86523.0 66176.0 64488.0 68700.0 60298.0 57180.0 True False 68704.5688766005 62455.21772274587 55509.73889911753 61728.298243724435 69569.43926055256 62705.61406381005 58379.22978731139 66896.69779366671 61179.74417739137 67546.28136336898 1.0171480574482028 0.9246285134005312 0.8218030331011089 0.9138667147589313 1.029952172885727 0.9283355470966893 0.8642848815504303 0.9903831335109656 0.9057455561213137 1.0 16.043588726357257 -6.057561058722123 24.999796570289682 0.9492239165955024 0.9125855942484157 0.05845493893606735 0.06296863400140058 827.9854721935238 359606.8686336283 0.01914091671265123 0.02471087764695448 8.758685680713982e-07 6.057561058722123 -0.03663832234708675 QNPEQS(ph)ADEDAEK ddPTM_PC-9_Lapatinib_30min_R1 1 QNPEQSADEDAEK 13 0 Q99613-2;Q99613;B5ME19;H3BPE3 Q99613-2 EIF3C;EIF3CL Eukaryotic translation initiation factor 3 subunit C;Eukaryotic translation initiation factor 3 subunit C-like protein 1 QNPEQS(1)ADEDAEK 165.89 0.00030641 6363400.0 14345.0 17134.0 12396.0 12336.0 15065.0 13253.0 14109.0 16918.0 13380.0 12750.0 True False 14140.437669449188 17094.327275709824 11376.848729943764 13243.230591689653 14178.906318929581 12686.200084251925 14839.494984132803 17704.07204219546 11873.003502353722 14953.820511692898 0.9456070211884849 1.1431411298766887 0.7607988019548463 0.8856085026120464 0.9481795175916826 0.8483584562441522 0.9923547612818611 1.1839163127812085 0.7939779331355368 1.0 13.868226501371575 -7.499130525487991 23.786591960085406 1.0109953384897177 0.9238967122052472 0.06395051504847127 0.12649947245776152 1028.7304707122728 1030397.1179415099 0.05275800192803564 0.03529820235981655 3.168615005220641e-08 7.499130525487991 -0.08709862628447052 QNPGLAYGNPYSGIQES(ph)SSPSPLSIKK ddPTM_PC-9_Lapatinib_30min_R1 1 QNPGLAYGNPYSGIQESSSPSPLSIKK 27 1 Q13137-5;Q13137-2;Q13137;Q13137-3;Q13137-4 Q13137-5 CALCOCO2 Calcium-binding and coiled-coil domain-containing protein 2 1 QNPGLAYGNPY(0.02)S(0.069)GIQES(0.29)S(0.29)S(0.29)PS(0.035)PLS(0.006)IKK 65.811 0.00017298 4500900.0 17403.0 7851.6 11204.0 10866.0 14800.0 14733.0 13777.0 12970.0 16616.0 10427.0 True False 17154.830028680666 7833.420102600867 10282.850368690693 11665.121887913401 13929.493097919532 14102.903934300446 14490.305648621272 13572.63354931287 14744.531105763039 12229.29305689583 1.402765470487064 0.6405456199435643 0.8408376772762363 0.9538672295808378 1.13902684587847 1.153206801790405 1.1848849791403524 1.109846128158615 1.2056732173450468 1.0 13.578053387438546 -6.232910798347646 4.610001196553597 1.1421617020872692 0.9253416961477148 0.16286406814009224 0.18536895782861607 0.3056334728518857 16.54521904586746 0.05470051296580015 0.0690118136750236 5.849102090860766e-07 6.232910798347646 -0.21682000593955442 QNPQS(ph)PPQDSSVTSK ddPTM_PC-9_AZD4547_30min_R2 1 QNPQSPPQDSSVTSK 15 0 C9JEF4;C9J172;Q9BRX7;A0A2R8YCS4;E7EP63;E7ER52;A6NDI8;Q9UBN7 C9JEF4 HDAC6 Histone deacetylase 6 1 QNPQS(0.996)PPQDS(0.002)S(0.002)VTSK 209.33 8.081699999999997e-63 0.0 7906.7 6202.5 8379.6 7902.9 6358.2 8177.5 7552.6 9553.3 6609.6 9143.8 True False 10420.866130423383 8207.336828501715 8268.48102886662 6081.008503587854 5475.473680520883 7666.159632276448 8224.766768675108 8077.056997994692 6958.969962234161 8823.678345156108 1.1810115603481937 0.9301491404667145 0.9370786995432271 0.6891693311697061 0.6205432095704994 0.8688167601309835 0.9321245003440338 0.915384342226019 0.7886699503336263 1.0 13.107164485121505 -4.669893141111601 1.560494705283203 0.8295773924692548 1.3812001638374352 0.4577724200707459 0.11083495000142662 1.3632898003588774 2.5761362020459297 0.03352444679877843 1.254288383499654 2.1384882033965255e-05 4.669893141111601 0.5516227713681804 QNPQS(ph)PPQDSSVTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QNPQSPPQDSSVTSK 15 0 C9JEF4;C9J172;Q9BRX7;A0A2R8YCS4;E7EP63;E7ER52;A6NDI8;Q9UBN7 C9JEF4 HDAC6 Histone deacetylase 6 1 QNPQS(0.999)PPQDS(0.001)SVTSK;QNPQS(0.866)PPQDS(0.052)S(0.052)VT(0.026)S(0.003)K 157.91 2.4896e-14 0.0 18467.1 17889.3 20810.8 15667.1 23064.4 14033.3 20265.0 20536.3 17331.2 11847.8 True False 21593.215288149153 19665.231477735044 21307.008397398502 14789.323180423524 18545.096389180748 13297.369043787241 18345.35249410535 19997.243885008447 17584.636012590898 13995.712352866796 1.542845033088018 1.4050897147587444 1.5223954208400192 1.05670385383379 1.325055554273526 0.9501030536015188 1.3107837623104337 1.4288121519525467 1.2564302244314822 1.0 13.772697298528426 -5.74648844516528 24.97751689025332 1.2082675076719034 1.4816081185490642 0.4600199916819938 0.14811249958395042 236.2415586812272 394669.56646217994 0.040541702006278414 0.06986121466675364 1.7927162487219265e-06 5.74648844516528 0.2733406108771608 QNS(ph)IENDIEEK ddPTM_PC-9_AZD4547_30min_R2 2 QNSIENDIEEK 11 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;F5GXF5;Q12830-2 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 QNS(1)IENDIEEK;QNS(1)IENDIEEK 142.95 0.00014608 3575900.0 13364.3 12834.3 12925.0 20219.9 18668.8 15698.0 15788.3 18580.7 17104.8 16579.8 True False 17613.869405291374 16982.736486584367 12753.606054955024 15558.514449340895 16076.959366944777 14716.401578413419 17193.42811401017 15709.479757009633 18008.92480785871 15999.346248498365 1.1009118205029498 1.0614644012831649 0.7971329488635841 0.9724468867470855 1.0048510181129242 0.9198126817084569 1.074633166066012 0.9818826040147773 1.1256037920642512 1.0 13.96572533570468 -7.272930605422423 24.870392822091535 1.0440201074343405 0.9729888408926122 0.1371536998778734 0.08506033402095808 1524.4465642268356 3299337.2478762735 0.03651912241076784 0.024850965339083205 5.334201222367052e-08 7.272930605422423 -0.07103126654172831 QNS(ph)IENDIEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QNSIENDIEEK 11 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;F5GXF5;Q12830-2 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 QNS(1)IENDIEEK;QNS(1)IENDIEEK 121.76 0.00073603 1746400.0 16274.7 14780.9 13166.5 19713.4 16118.2 19238.7 16923.7 13235.5 13529.8 17736.0 True False 19029.685270022987 16248.250068434987 13480.439294229313 18608.92210970513 12959.954415466835 18229.788704204268 15320.564619022498 12888.082149171432 13727.647729133145 20951.396401901246 0.9082776586813148 0.7755211040234307 0.6434148366839177 0.8881948368852615 0.6185723455783967 0.8700989831183756 0.7312431269560737 0.6151419171278673 0.6552139755175184 1.0 14.354758781706105 -4.797832033872126 4.0673120918413606 0.7406973888775708 0.9198002416538151 0.11634778732465922 0.12387372150859592 0.4090697467362375 12.664205185517204 0.029309918528678428 0.20570275379994804 1.59282464290772e-05 4.797832033872126 0.17910285277624438 QNS(ph)IENDIEEK ddPTM_PC-9_Lapatinib_30min_R1 2 QNSIENDIEEK 11 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;F5GXF5;Q12830-2 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 QNS(1)IENDIEEK;QNS(1)IENDIEEK 153.14 6.8569e-05 3711000.0 29081.0 16218.6 17831.2 17618.4 21445.0 24017.0 20365.8 21956.0 27515.0 35025.0 True False 28666.299607197743 16181.04682816782 16365.187566422486 18914.115909259468 20183.647262492177 22989.848896361476 21420.241473375278 22976.155914318704 24415.97095420499 41079.02458212109 0.6978330157253596 0.3939004636251838 0.398383061255674 0.4604324494474851 0.4913370623526623 0.559649337593264 0.521439875734003 0.5593160048965394 0.5943658887370856 1.0 15.326114304943536 -9.695904312714132 0.48261649658095135 1.0679414613314053 0.479095236174129 0.7667112881415008 0.08125544954811961 2.526808882025197 0.6517494023993186 0.3950352702968562 0.042319670330885115 2.014167978817775e-10 9.695904312714132 -0.5888462251572764 QNS(ph)PVTQDGIQESPWQDR ddPTM_PC-9_AZD4547_30min_R2 4 QNSPVTQDGIQESPWQDR 18 0 O75815 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 QNS(0.939)PVT(0.061)QDGIQESPWQDR;QNS(0.921)PVT(0.079)QDGIQESPWQDR;QNS(1)PVTQDGIQESPWQDR;QNS(1)PVTQDGIQESPWQDR 337.64 6.005899999999997e-199 57201000.0 43996.0 41044.7 64033.0 88777.0 72242.0 64411.0 59468.0 70417.0 56194.0 62062.0 True False 57985.81282635073 54311.59660214501 63183.88058158103 68310.83424097729 62212.44528768982 60383.36998771731 64760.536795219035 59535.67067168337 59164.30011767525 59889.22827020264 0.9682177329909102 0.9068675314550223 1.0550124355671087 1.140619710990077 1.0387919010578246 1.0082509281182461 1.0813386424523368 0.9940964742954422 0.9878955168823227 1.0 15.870008921484635 -5.267443755741776 24.912652159795044 1.0421826625978516 0.9375426301396141 0.42857614640987096 0.046337010142241536 386.025682578885 1601659.0937977922 0.012730695376870478 0.027637266511707736 5.402020702871195e-06 5.267443755741776 -0.1046400324582375 QNS(ph)PVTQDGIQESPWQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QNSPVTQDGIQESPWQDR 18 0 O75815 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 QNS(0.992)PVT(0.008)QDGIQESPWQDR;QNS(0.974)PVT(0.026)QDGIQESPWQDR;QNS(0.787)PVT(0.213)QDGIQESPWQDR;QNS(0.998)PVT(0.002)QDGIQESPWQDR 294.93 6.430499999999999e-121 43976400.0 53477.6 50430.2 63179.299999999996 71863.1 87379.7 83923.0 88960.0 98264.0 78771.0 63296.6 True False 62530.30144925437 55436.57697441901 64685.73412082954 67836.84349031355 70258.275045425 79521.93014200202 80533.06478537452 95684.67411931427 79922.87685490897 74771.77252439008 0.8362821869557444 0.7414104962716506 0.8651090102181203 0.9072520444554876 0.9396363450192009 1.0635287549999228 1.0770517010159835 1.2796897932050832 1.0688910287480298 1.0 16.190206113231785 -6.475111238297194 1.0196518470748523 1.1336455160515346 0.7985108014106369 0.7381350807153129 0.07453817268395524 0.24361328258245346 0.5428826437887453 0.036196830503061064 0.044341363269268456 3.34879653555898e-07 6.475111238297194 -0.3351347146408977 QNS(ph)PVTQDGIQESPWQDR ddPTM_PC-9_Lapatinib_30min_R1 4 QNSPVTQDGIQESPWQDR 18 0 O75815 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 QNS(0.98)PVT(0.02)QDGIQESPWQDR;QNS(0.998)PVT(0.002)QDGIQESPWQDR;QNS(0.849)PVT(0.151)QDGIQESPWQDR;QNS(0.822)PVT(0.178)QDGIQESPWQDR 321.67 1.3028999999999998e-157 44474600.0 71457.8 63071.0 71039.0 66170.0 77258.0 78011.0 78980.0 81902.0 88922.0 67674.0 True False 70438.79866824436 62924.962974570706 65198.44763847012 71036.36253664932 72713.83633507213 74674.65138252296 83069.19794789195 85707.46591795103 78906.66796982806 79371.36073006313 0.8874586251305703 0.7927917878159408 0.8214354275745105 0.8949873340113118 0.9161218311774596 0.9408261455474681 1.0465890616440976 1.079828607316392 0.994145334589696 1.0 16.276330918579177 -6.689977623371071 1.1408993784981367 1.0379532853157565 0.8342719643885965 0.8242939410342176 0.03713024976100402 0.18242310292417407 0.5046789207156416 0.019133097338167326 0.018515644069120787 2.0418431460738255e-07 6.689977623371071 -0.20368132092715996 QNS(ph)QLPAQVQNGPSQEELEIQR ddPTM_PC-9_AZD4547_30min_R2 2 QNSQLPAQVQNGPSQEELEIQR 22 0 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;A0A0U1RQP7;A0A075B6E5;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 1 QNS(1)QLPAQVQNGPSQEELEIQR;QNS(1)QLPAQVQNGPSQEELEIQR 126.75 3.2362e-06 7624500.0 16062.800000000001 15326.5 17691.8 29481.0 29269.0 24490.0 28687.0 48439.0 37410.0 30817.0 True False 21170.43627300452 20280.491398957118 17457.195172383228 22684.610926909565 25205.50456971561 22958.636428547885 31240.087425917256 40953.865567486115 39387.41622597131 29738.106209964768 0.7118959130595426 0.6819698354618643 0.5870311663132604 0.7628128962465105 0.8475827072427915 0.7720275214046687 1.0505069558010118 1.3771510962511502 1.3244762779404295 1.0 14.860025155773487 -7.372268267216429 2.320601820243272 1.2634840522283979 0.7164530723617785 0.8045894897779954 0.11339207577338392 0.12477092775851963 1.3115493942619527 0.058615257400253994 0.035268798279341776 4.2435735399795126e-08 7.372268267216429 -0.5470309798666194 QNS(ph)QLPAQVQNGPSQEELEIQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QNSQLPAQVQNGPSQEELEIQR 22 0 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;A0A0U1RQP7;A0A075B6E5;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 1 QNS(1)QLPAQVQNGPSQEELEIQR 82.126 0.0018035999999999998 0.0 7057.7 6729.8 5666.9 7786.9 9824.7 7376.0 10875.0 13536.0 8828.6 6404.4 True False 8252.429214070993 7397.89006830124 5802.020387837927 7350.625238470425 7899.620562199067 6989.189575294106 9844.841271818195 13180.694342577508 8957.70157292975 7565.467022797497 1.0908023508930025 0.9778497541538035 0.7669084235453456 0.9716023103822043 1.0441682632935474 0.9238279083410373 1.301286654498938 1.742218200523417 1.184024931433439 1.0 12.885213428660908 -7.320088846534473 5.016758409007323 1.376270397541901 0.9581719048538867 0.4151880521063255 0.19446032943716943 0.1769131151952243 9.40859172011016 0.08041165407039336 0.053969418953016435 4.785321857700759e-08 7.320088846534473 -0.41809849268801436 QNS(ph)QLPAQVQNGPSQEELEIQR ddPTM_PC-9_Lapatinib_30min_R1 1 QNSQLPAQVQNGPSQEELEIQR 22 0 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;A0A0U1RQP7;A0A075B6E5;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 1 QNS(1)QLPAQVQNGPSQEELEIQR 111.64 6.3529e-06 2864300.0 14283.0 16843.0 20817.0 19419.0 29824.0 22696.0 29696.0 18455.0 25839.0 27050.0 True False 14079.32180081859 16804.001068330836 19105.5066159438 20847.138039884983 28069.81095624 21725.344986960074 31233.513576356076 19312.486673289834 22928.739723267405 31725.556458140614 0.443784865346496 0.5296676542301914 0.6022118679353038 0.6571086646625457 0.8847696964204841 0.6847900371936727 0.984490646131495 0.6087359475875906 0.7227214360611792 1.0 14.953357848339532 -5.663055708979527 1.2828176304638037 0.7985544715314717 0.4635186609823805 0.5442317163631569 0.12054264366215724 0.40424909717867347 1.2787673227753065 0.03988943232704775 0.11672939734806938 2.172422494220606e-06 5.663055708979527 -0.33503581054909126 QNS(ph)SSSDSGGSIVR ddPTM_PC-9_AZD4547_30min_R2 2 QNSSSSDSGGSIVR 14 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 QNS(0.946)S(0.011)S(0.021)S(0.021)DS(0.002)GGSIVR;QNS(0.684)S(0.092)S(0.191)S(0.015)DS(0.018)GGSIVR 154.52 0.0001196 162111000.0 13689.4 14290.3 20579.6 26548.0 26539.0 19631.699999999997 18712.4 28003.0 22050.0 24556.0 True False 18042.34444279129 18909.360012952533 20306.70105752824 20427.768762511278 22854.51794648544 18404.126695562416 20377.767349277867 23675.779794923787 23215.517984032806 23696.3019142647 0.7613991629609581 0.7979878076067843 0.8569565466797169 0.8620656858787814 0.9644761460743999 0.7766666192113083 0.8599555923538794 0.9991339526557703 0.9797105923121924 1.0 14.532374306764103 -1.5228787452804022 0.12748743639015953 1.0592535489657693 0.0966172230992216 0.5933644011048872 0.05633828004008171 66.11544016664239 0.5748597139159131 0.34826505110532624 11.398530034828228 0.029999999999995534 1.5228787452804022 -0.9626363258665477 QNS(ph)SSSDSGGSIVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QNSSSSDSGGSIVR 14 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 QNS(0.804)S(0.091)S(0.031)S(0.031)DS(0.04)GGS(0.002)IVR;QNS(0.445)S(0.445)S(0.02)S(0.006)DS(0.083)GGS(0.001)IVR 161.24 0.0005070000000000001 85010000.0 23983.0 22279.3 26791.0 33018.0 35734.0 33342.0 30300.0 32235.0 37603.0 25993.0 True False 28042.848214158228 24491.041665235793 27429.799045433312 31168.108505800305 28732.17921866536 31593.48682476354 27429.764646996886 31388.8654058057 38152.87273711317 30705.325139525212 0.9132894078382603 0.7976154479377218 0.8933238427143212 1.015071762444208 0.9357392923900377 1.0289253307432022 0.8933227224383993 1.022261293869206 1.2425490550497755 1.0 14.906201259449942 -6.393902398994723 0.4652509154473704 1.0803686041606722 0.8291098775291169 0.40914187429830295 0.08734020034111463 1.4175489964199521 0.6001662766483098 0.08025743174986914 0.16377083456714817 4.0373611625548216e-07 6.393902398994723 -0.25125872663155524 QNS(ph)SSSDSGGSIVR ddPTM_PC-9_Lapatinib_30min_R1 1 QNSSSSDSGGSIVR 14 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 QNS(0.663)S(0.031)S(0.064)S(0.137)DS(0.092)GGS(0.013)IVR 137.32 6.9379e-05 25679000.0 34731.0 25679.0 30508.0 32441.0 37564.0 35217.0 33820.0 32189.0 43390.0 28227.0 True False 34235.72957111465 25619.541853213068 27999.750004285605 34826.81936000354 35354.55937366549 33710.85100483666 35571.034117469084 33684.61845172183 38502.96128304395 33105.999339886715 1.0341246376413358 0.7738640235622241 0.8457606041981337 1.0519790990886522 1.0679200168734877 1.0182701527520786 1.0744588541875686 1.017477772106942 1.1630206624409274 1.0 15.014805059833405 -5.767648528053909 24.971885407284145 1.0565627965176396 0.8735111710312486 0.5300127217403372 0.07381950778460608 98.27508906482984 395243.34859134094 0.0197623736311584 0.030156898931271457 1.7074636702086324e-06 5.767648528053909 -0.18305162548639098 QNS(ph)TSLTGKPGALPANLDDMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QNSTSLTGKPGALPANLDDMK 21 1 W0Z7M9;A0A499FIJ6;Q969V6;E7ER32;A0A087X287;A0A087WU73;A0A494BZX7;B0QY83 W0Z7M9 mkl1;MKL1 MKL/myocardin-like protein 1 1 QNS(0.682)T(0.242)S(0.056)LT(0.02)GKPGALPANLDDMK 54.656000000000006 0.027975999999999997 13826000.0 21584.0 15603.0 14343.0 18544.0 20735.0 20552.0 19746.0 26112.0 24027.0 16733.0 True False 25237.744896568052 17151.96272336537 14684.991516130416 17505.03980045917 16672.125597442933 19474.216940271748 17875.51593133996 25426.58766795093 24378.349420381808 19766.560441644884 1.2767899084453906 0.8677262174166129 0.7429209325255981 0.8855885601411431 0.8434510215706276 0.9852101986971281 0.9043311295413438 1.286343556989374 1.2333126692603862 1.0 14.270774230611853 -7.751311245712168 24.99808851829932 1.194871085135309 0.9170365315625116 0.3560867627956965 0.14872890517215004 191.79775464919388 473394.8355702439 0.07106653119853537 0.04042491837012142 1.7729184284981305e-08 7.751311245712168 -0.2778345535727974 QNS(ph)VQEQPGTACLSK ddPTM_PC-9_AZD4547_30min_R2 1 QNSVQEQPGTACLSK 15 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 QNS(1)VQEQPGTACLSK 249.89 4.237799999999999e-127 0.0 6686.8 5411.9 7957.7 14745.0 11373.0 7515.8 10930.0 15355.0 15649.0 12831.0 True False 8813.06330591968 7161.19083952736 7852.175698531186 11345.768057979083 9794.055262269823 7045.835837879955 11902.748825784352 12982.237572797727 16476.174191933318 12381.790595452447 0.7117761553128286 0.5783647190865515 0.6341712564106127 0.9163269214184683 0.7910047570879578 0.5690482150835059 0.9613107840925661 1.0484943573157999 1.3306778260314502 1.0 13.595932344859255 -7.573589339799947 2.5171238841250387 1.1531180488499184 0.7060179798448781 0.6977290705408711 0.12674564634682142 0.16385407027818655 2.0867713738865428 0.07298959451301007 0.03794670763855794 2.6693815855078597e-08 7.573589339799947 -0.4471000690050403 QNS(ph)VQEQPGTACLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QNSVQEQPGTACLSK 15 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 QNS(0.997)VQEQPGT(0.003)ACLSK 210.2 6.812999999999998e-63 0.0 5097.0 6059.5 4077.3 5015.5 10602.0 10417.0 8428.1 13148.0 8037.6 6355.0 True False 5959.821429661195 6661.047114159615 4174.518295246358 4734.497795470394 8524.6142070938 9870.714181919564 7629.729353840086 12802.878931457532 8155.13469435472 7507.111193847675 0.7938901230802955 0.8872983151786219 0.5560751915686973 0.6306683986978201 1.1355385563064528 1.3148485385442192 1.016333601145125 1.7054335017642888 1.0863212870801915 1.0 12.874042136731118 -6.372488913744111 4.290053316028703 1.2525430438688905 0.7187542824420122 0.5767254843168252 0.20675378770323083 0.15987887909507462 4.929393621308908 0.06472694529685745 0.07389728000113288 4.2414181086046995e-07 6.372488913744111 -0.5337887614268783 QNSNSQS(ph)TPGSSGQR ddPTM_PC-9_Lapatinib_30min_R1 2 QNSNSQSTPGSSGQR 15 0 A8CG34-2;A8CG34;A6NF01;Q96HA1;Q96HA1-2;Q96HA1-3 A8CG34-2;Q96HA1 POM121C;POM121B;POM121 Nuclear envelope pore membrane protein POM 121C;Putative nuclear envelope pore membrane protein POM 121B;Nuclear envelope pore membrane protein POM 121 1 QNSNS(0.001)QS(0.499)T(0.499)PGSSGQR;QNSNS(0.035)QS(0.482)T(0.482)PGS(0.001)SGQR 229.02 1.3686000000000002e-24 4952340.0 5234.8 10254.8 9311.8 5524.17 8439.3 5135.4 5058.9 4396.6 8613.8 6891.16 True False 5160.15079205525 10231.05564065303 8546.219748587468 5930.435889890902 7942.91696630218 4915.770913202096 5320.825088612191 4600.882086577408 7643.623136664761 8082.287824106482 0.6384517483607086 1.2658613332400224 1.0574010644730132 0.733757077074464 0.9827560140349605 0.6082152752021731 0.6583315522050741 0.5692549172592783 0.9457251836375653 1.0 12.980548013938623 -5.76323686211105 24.999999915578826 0.7630282224785362 1.0151004086840374 0.16020318515846654 0.20437271815924757 67.22010953165596 934944.3528649969 0.05567777778680919 0.0876107499895982 1.7248968849802769e-06 5.76323686211105 0.2520721862055012 QNSNSQST(ph)PGSSGQR ddPTM_PC-9_AZD4547_30min_R2 4 QNSNSQSTPGSSGQR 15 0 A8CG34-2;A8CG34;A6NF01;Q96HA1;Q96HA1-2;Q96HA1-3 A8CG34-2;Q96HA1 POM121C;POM121B;POM121 Nuclear envelope pore membrane protein POM 121C;Putative nuclear envelope pore membrane protein POM 121B;Nuclear envelope pore membrane protein POM 121 1 QNSNS(0.004)QS(0.023)T(0.972)PGSSGQR;QNS(0.002)NS(0.074)QS(0.039)T(0.881)PGS(0.004)SGQR;QNSNS(0.01)QS(0.051)T(0.936)PGS(0.001)S(0.003)GQR;QNS(0.127)NS(0.007)QS(0.096)T(0.768)PGSS(0.001)GQR 235.78 1.5737999999999998e-31 10363840.0 11070.759999999998 9613.04 13700.710000000001 16747.0 17917.6 17276.16 17071.45 21928.8 19599.0 22375.5 True False 14591.031393886968 12720.26718675697 13519.029633515122 12886.237888570755 15430.05052028891 16195.878984133196 18590.775978219226 18540.207833693712 20634.963127848478 21592.140555572136 0.6757565956156005 0.5891156161205304 0.6261088194901713 0.596802241788172 0.7146142125453598 0.750082139491892 0.8609973582920954 0.8586553883333798 0.9556701001801952 1.0 14.398218652823228 -7.30076238991194 0.7246024570348464 0.9870941399084234 0.6085277014576022 0.9467304408685604 0.03253897636407032 0.14159116522153947 0.14588867297709288 0.027504657822596795 0.017153416409550423 5.003081874482176e-08 7.30076238991194 -0.3785664384508213 QNSNSQST(ph)PGSSGQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QNSNSQSTPGSSGQR 15 0 A8CG34-2;A8CG34;A6NF01;Q96HA1;Q96HA1-2;Q96HA1-3 A8CG34-2;Q96HA1 POM121C;POM121B;POM121 Nuclear envelope pore membrane protein POM 121C;Putative nuclear envelope pore membrane protein POM 121B;Nuclear envelope pore membrane protein POM 121 1 QNSNSQS(0.035)T(0.964)PGSSGQR;QNSNS(0.002)QS(0.022)T(0.976)PGSSGQR;QNS(0.002)NS(0.04)QS(0.324)T(0.633)PGSSGQR;QNSNS(0.019)QS(0.322)T(0.659)PGS(0.001)SGQR 216.72 2.1619000000000002e-17 10037770.0 13761.300000000001 17488.75 16581.6 14802.4 29746.5 20528.9 17644.399999999998 18331.13 18520.6 14795.970000000001 True False 16090.816291935784 19224.917520877774 16976.968230068185 13973.069518028296 23917.886862036972 19452.328344936985 15972.994697606344 17849.957260937703 18791.428737467166 17478.362236165925 0.9206135034002754 1.0999267128757584 0.9713134446281091 0.7994495896826913 1.3684283766900365 1.1129377044656141 0.9138725060037547 1.021260288564273 1.075125259653005 1.0 14.0932823867874 -4.741263552464332 23.88506461693907 1.0398188501777295 0.9206127843095677 0.06095268303034784 0.14087331527811112 2812.311522268351 3329036.4005088974 0.035896853756432937 1.33227075887245 1.8144142477382083e-05 4.741263552464332 -0.11920606586816174 QNSNSQST(ph)PGSSGQR ddPTM_PC-9_Lapatinib_30min_R1 2 QNSNSQSTPGSSGQR 15 0 A8CG34-2;A8CG34;A6NF01;Q96HA1;Q96HA1-2;Q96HA1-3 A8CG34-2;Q96HA1 POM121C;POM121B;POM121 Nuclear envelope pore membrane protein POM 121C;Putative nuclear envelope pore membrane protein POM 121B;Nuclear envelope pore membrane protein POM 121 1 QNSNS(0.004)QS(0.038)T(0.923)PGS(0.028)S(0.007)GQR;QNSNS(0.017)QS(0.31)T(0.672)PGSSGQR 158.91 0.00043074 4200190.0 5605.3 9660.400000000001 8987.0 6987.1 7076.7 7508.2 6027.2 3413.0 10682.4 6525.9 True False 5525.367394113871 9638.031937333213 8248.12355082322 7500.954642282319 6660.462419327509 7187.091788469056 6339.258924683905 3571.580439769068 9479.235621341068 7653.893119784839 0.7219028679445679 1.2592326266510698 1.077637670364423 0.9800182109798237 0.8702058305610026 0.9390112555780104 0.8282398023428514 0.46663578702670333 1.238485496594907 1.0 12.901978039779681 -6.1567315505244835 2.6854594019132674 0.8606804069660076 1.0427101713142644 0.0557535322510343 0.2181765898698184 0.618031533078529 8.677163910060933 0.06740033260967072 0.09115707762049391 6.970572514094994e-07 6.1567315505244835 0.1820297643482568 QNSNSQSTPGS(ph)SGQR ddPTM_PC-9_AZD4547_30min_R2 1 QNSNSQSTPGSSGQR 15 0 A8CG34-2;A8CG34;A6NF01;Q96HA1;Q96HA1-2;Q96HA1-3 A8CG34-2;Q96HA1 POM121C;POM121B;POM121 Nuclear envelope pore membrane protein POM 121C;Putative nuclear envelope pore membrane protein POM 121B;Nuclear envelope pore membrane protein POM 121 1 QNSNS(0.001)QS(0.001)T(0.002)PGS(0.499)S(0.499)GQR 107.13 0.0041286000000000005 0.0 0.0 658.66 661.78 1909.5 805.51 788.23 735.92 1237.8 550.09 723.04 True False 0.0 871.5589642016831 653.0043648006292 1469.294276480913 693.6788406146986 738.9418534942542 801.415454334055 1046.52645181433 579.166634369007 697.7265896762478 0.0 1.2491411064126068 0.9359029374294447 2.1058309919974243 0.9941986601608126 1.0590707942449644 1.148609593201715 1.499909086594978 0.8300767706699357 1.0 9.446518004158044 -4.7607645696715775 24.976723910175455 1.2253670092062827 1.4123867150647912e-06 0.5134205362467719 0.35056732514895844 12.865470140744703 475838.7005780816 0.08471314968211757 0.4918130007250602 1.7347441448690525e-05 4.7607645696715775 -1.2253655968195676 QNSNSQSTPGS(ph)SGQR ddPTM_PC-9_Lapatinib_30min_R1 1 QNSNSQSTPGSSGQR 15 0 A8CG34-2;A8CG34;A6NF01;Q96HA1;Q96HA1-2;Q96HA1-3 A8CG34-2;Q96HA1 POM121C;POM121B;POM121 Nuclear envelope pore membrane protein POM 121C;Putative nuclear envelope pore membrane protein POM 121B;Nuclear envelope pore membrane protein POM 121 1 QNSNSQSTPGS(0.888)S(0.112)GQR 70.167 0.02427 602630.0 571.41 524.41 0.0 0.0 0.0 0.0 457.49 676.48 407.19 0.0 True False 563.2615886162399 523.1957608646546 0.0 0.0 0.0 0.0 481.176593684238 707.9117304116559 361.3279742992087 0.0 0.0 QNSNSQSTPGSS(ph)GQR ddPTM_PC-9_Lapatinib_30min_R1 1 QNSNSQSTPGSSGQR 15 0 A8CG34-2;A8CG34;A6NF01;Q96HA1;Q96HA1-2;Q96HA1-3 A8CG34-2;Q96HA1 POM121C;POM121B;POM121 Nuclear envelope pore membrane protein POM 121C;Putative nuclear envelope pore membrane protein POM 121B;Nuclear envelope pore membrane protein POM 121 1 QNSNSQSTPGS(0.235)S(0.765)GQR 142.4 1.0929000000000002e-06 0.0 0.0 0.0 428.82 0.0 0.0 604.31 515.86 0.0 973.3 620.64 True False 0.0 0.0 393.5640748930688 0.0 0.0 578.4650700154139 542.5687066776346 0.0 863.6767046966285 727.9167970491831 0.0 0.0 0.5406717862377847 0.0 0.0 0.7946857008388677 0.7453718733749387 0.0 1.186504705205027 1.0 9.507629745494679 -7.514945418969316 0.37935501407275835 1.0508666320066538 3.1896338240758214e-14 0.46484691984335735 0.33253335338532847 1.2123280330354769 0.4616578854348749 0.40585614563668454 0.43022805997560715 3.0553050720917634e-08 7.514945418969316 -1.0508666320066218 QNSPAGNKENIKPNET(ph)SPSFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QNSPAGNKENIKPNETSPSFSK 22 2 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;F8WB06 Q99700;F8WB06 ATXN2 Ataxin-2 1 QNSPAGNKENIKPNET(0.363)S(0.264)PS(0.363)FS(0.01)K 66.77199999999999 0.001254 22757000.0 59800.0 39967.0 44715.0 61920.0 61760.0 51478.0 62357.0 68923.0 55371.0 48890.0 True False 69922.95889616248 43934.65962729884 45781.175182581814 58450.82314734852 49658.571347869605 48778.40305816025 56450.09353441539 67113.84427995486 56180.69612335966 57753.36998697296 1.2107165159701423 0.7607289347307159 0.792701364317067 1.0120764062864709 0.8598385056849627 0.8445983856727818 0.977433759227357 1.162076676998992 0.9727691411952577 1.0 15.817617511734298 -7.523631043823753 24.984645641490623 1.054404811376715 0.9037232314475897 0.17100304177070724 0.12860700776047623 40.10586559858507 1331788.8720134094 0.05816041133201267 0.03396055827605215 2.994807804106085e-08 7.523631043823753 -0.15068157992912534 QNSPAGNKENIKPNET(ph)SPSFSK ddPTM_PC-9_Lapatinib_30min_R1 1 QNSPAGNKENIKPNETSPSFSK 22 2 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;F8WB06 Q99700;F8WB06 ATXN2 Ataxin-2 1 QNSPAGNKENIKPNET(0.504)S(0.384)PS(0.111)FS(0.001)K 78.236 0.00031448 38706000.0 183460.0 141310.0 149870.0 127050.0 135210.0 124590.0 134850.0 120560.0 147400.0 108680.0 True False 180843.82675755623 140982.8053770603 137548.26711493003 136393.68082637546 127257.21363308784 119261.5761334752 141831.87317388243 126161.65772591851 130798.25980918825 127465.19319300292 1.418770271533888 1.106049438638433 1.0791045278271356 1.0700464762945392 0.998368342331697 0.9356403355768965 1.1127106123718498 0.9897734006089753 1.0261488374409673 1.0 16.959743819847333 -1.8105918017101175 0.9944728885039508 1.0177262258921413 199.9992860165485 0.8656339293666455 0.046533771872958415 278.58169330114566 0.7528577435373786 0.014773964763932206 125795.21842281621 0.01546707524421765 1.8105918017101175 198.98155979065635 QNSPAGNKENIKPNETS(ph)PSFSK ddPTM_PC-9_AZD4547_30min_R2 1 QNSPAGNKENIKPNETSPSFSK 22 2 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;F8WB06 Q99700;F8WB06 ATXN2 Ataxin-2 1 QNS(0.001)PAGNKENIKPNET(0.192)S(0.594)PS(0.192)FS(0.022)K 48.968 0.014328 35263000.0 35292.0 30690.0 38393.0 44774.0 44282.0 46417.0 41827.0 41336.0 38772.0 41085.0 True False 46514.12188079759 40609.9423243398 37883.88373445943 34452.046051404235 38134.20866295898 43514.537652262436 45549.52197036433 34948.47100678393 40821.4087653932 39646.62665530076 1.1732176430848662 1.02429754433875 0.9555386404960219 0.8689779927795697 0.9618525428281408 1.0975596494145747 1.1488877065477738 0.8814992334817298 1.0296313257696887 1.0 15.274910498575663 -4.7795106095492645 3.667991253521678 0.9923419238159606 1.193344401148437 0.3019763473391145 0.08177374087617777 0.36535673060256224 8.456000458530138 0.022255869376576445 0.2023651547995754 1.6614580888632887e-05 4.7795106095492645 0.20100247733247645 QNSPAGNKENIKPNETS(ph)PSFSK ddPTM_PC-9_Lapatinib_30min_R1 1 QNSPAGNKENIKPNETSPSFSK 22 2 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;F8WB06 Q99700;F8WB06 ATXN2 Ataxin-2 1 QNSPAGNKENIKPNET(0.051)S(0.918)PS(0.028)FS(0.003)K 78.456 0.00020765 34664000.0 109260.0 70049.0 88948.0 70852.0 86412.0 83690.0 72473.0 76843.0 90028.0 63273.0 True False 107701.93236416983 69886.80584429772 81635.03878920924 76062.69243534312 81329.41605252847 80110.7737909185 76225.29732688761 80413.40630916343 79888.09860313163 74209.65374402709 1.4513196993974444 0.9417481731603241 1.1000595565476519 1.0249703185209267 1.0959411875584235 1.079519573925601 1.0271614740288793 1.0835976487174441 1.0765189510072546 1.0 16.179319255111217 -4.751456055613177 24.999990663738828 1.0531187637372816 1.4513205069310506 0.864678215953966 0.04785594381696043 132.79510103597045 332519.473486407 0.011129261253660169 0.14691649374784888 1.772327370230293e-05 4.751456055613177 0.398201743193769 QNSS(ph)SSDSGGSIVR ddPTM_PC-9_AZD4547_30min_R2 1 QNSSSSDSGGSIVR 14 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 QNS(0.012)S(0.933)S(0.031)S(0.024)DSGGSIVR 201.75 2.145e-08 41835000.0 38887.0 43019.0 55245.0 73654.0 55538.0 69184.0 44699.0 74302.0 53490.0 57391.0 True False 51252.257100152325 56924.05046760421 54512.41520355823 56674.208242956316 47827.50735566179 64857.913543187344 48677.124406563125 62820.33319010202 56317.3721980007 55381.75855846086 0.9254357108586676 1.0278483737116313 0.9843027130677883 1.0233371008457803 0.8635967618322409 1.1711060687017274 0.8789378610139232 1.1343145256716436 1.016893895461124 1.0 15.75712324443685 -6.748519721778123 24.99994720140518 1.0385631246214846 0.9727250577335246 0.15777737127545854 0.08605368545742113 488.4388328551936 945143.4688727761 0.026746578446513018 0.02658460642203481 1.7843509574101634e-07 6.748519721778123 -0.06583806688796001 QNSS(ph)SSDSGGSIVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QNSSSSDSGGSIVR 14 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 QNS(0.012)S(0.915)S(0.03)S(0.024)DS(0.019)GGSIVR;QNS(0.012)S(0.918)S(0.065)S(0.005)DSGGSIVR 201.75 2.145e-08 130606000.0 31682.0 26217.0 26477.0 36346.0 43590.0 41295.0 42895.0 41634.0 39605.0 34958.0 True False 37045.13685197686 28819.6504978831 27108.312094581674 34309.651455321895 35048.852413433204 39129.41750430722 38831.675067093456 40541.15161486939 40184.14819970123 41295.60867262426 0.8970720626896794 0.6978865652848039 0.6564453937338949 0.8308305061517715 0.8487307377229153 0.9475442731577158 0.9403342465523654 0.9817303320617959 0.9730852623644741 1.0 15.333700754824614 -6.516050403452419 1.4626694532127347 0.9735065416944837 0.7491428600051331 0.698311023493684 0.06223308582922015 0.22456989622873097 0.984292742032531 0.026046505142578325 0.029006425913688686 3.047541276831383e-07 6.516050403452419 -0.2243636816893506 QNSS(ph)SSDSGGSIVR ddPTM_PC-9_Lapatinib_30min_R1 2 QNSSSSDSGGSIVR 14 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 QNS(0.048)S(0.474)S(0.474)S(0.004)DSGGSIVR;QNS(0.077)S(0.572)S(0.174)S(0.053)DS(0.122)GGS(0.002)IVR 232.01 2.0945999999999998e-21 160780000.0 32276.0 25650.0 31646.0 25264.0 30097.0 28648.0 25630.0 27326.0 36046.0 26143.0 True False 31815.738321306522 25590.6090009313 29044.188037092626 27121.99883823341 28326.753632978653 27422.791821749746 26956.995991446856 28595.665718467502 31986.119898792425 30661.782716642174 1.0376349808270613 0.8346092997078604 0.9472439455168544 0.8845538789730093 0.9238456189830037 0.8943639081645957 0.8791724943251755 0.9326158880822917 1.043191786804733 1.0 14.904153959184438 -8.160178544883648 4.7485327081035535 1.0206697916787462 0.9109081050114125 0.400575272724753 0.051392095074511215 0.19293998229419967 6.790248350921424 0.0344674218667377 0.012145543301080542 6.915466074333512e-09 8.160178544883648 -0.10976168666733366 QNSSSS(ph)DSGGSIVR ddPTM_PC-9_Lapatinib_30min_R1 1 QNSSSSDSGGSIVR 14 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 QNS(0.021)S(0.196)S(0.129)S(0.356)DS(0.298)GGSIVR 211.45 1.8865e-11 37793000.0 97830.0 78784.0 100380.0 89131.0 116030.0 122330.0 113170.0 100600.0 120940.0 108740.0 True False 96434.92626017536 78601.58048847436 92127.14387800539 95685.99107229956 109205.34352375694 117098.23106515808 119029.38885493716 105274.24325835584 107318.46364534069 127535.5641130577 0.7561414490995448 0.6163110739745946 0.7223643422029054 0.7502690856291336 0.8562736542016516 0.9181613919185151 0.9333035038714379 0.8254500930033316 0.8414787231442755 1.0 16.960540082423456 -6.166702119736326 1.922594108856636 0.8951810642825662 0.6884764274543751 0.7299580490118677 0.05611398899190323 0.17945285460353805 1.3070948330323786 0.01896109803751318 0.026670075772412205 6.812364549290012e-07 6.166702119736326 -0.20670463682819107 QNSSSSDSGGS(ph)IVR ddPTM_PC-9_AZD4547_30min_R2 1 QNSSSSDSGGSIVR 14 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 QNSSSS(0.001)DS(0.012)GGS(0.987)IVR 90.725 0.021026 0.0 7851.8 7701.7 8627.5 9850.2 11622.0 11843.0 7743.8 10773.0 2756.3 9634.6 True False 10348.50907241433 10191.12391004783 8513.093712891638 7579.388574072952 10008.485910322694 11102.455337823292 8432.983198271626 9108.280388912408 2901.992390902023 9297.295586544002 1.1130665875990597 1.0961385292296686 0.9156526899298177 0.8152250838450935 1.0764943221562193 1.194159660137288 0.907036150434617 0.9796698732580734 0.3121329599439738 1.0 13.182595408271473 -8.042678383284803 23.527063609558624 0.6526773081040568 1.01206060669403 0.3679854370163357 0.18715112221009134 245.14763205227126 135138.7195857209 0.12041643065829088 0.04552563808956565 9.06403589463198e-09 8.042678383284803 0.3593832985899733 QNT(ph)QSDIGGSGK ddPTM_PC-9_AZD4547_30min_R2 2 QNTQSDIGGSGK 12 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 QNT(0.452)QS(0.096)DIGGS(0.452)GK;QNT(0.786)QS(0.03)DIGGS(0.184)GK 111.88 0.0024954 9386300.0 22764.0 19552.7 27234.0 38341.0 31266.0 30045.0 36095.0 41566.0 33905.0 34622.0 True False 30002.478479385598 25872.727901111743 26872.85936562052 29502.07481254502 26925.255590444784 28166.281400396954 39307.38507471967 35142.929791658134 35697.14908157063 33409.894318116654 0.8980117744076979 0.7744031649654799 0.8043383528767584 0.8830340656464573 0.8059066375389417 0.843052095053281 1.1765192879824549 1.0518719232404676 1.0684604010319692 1.0 15.027987798709308 -7.243720897416657 23.35084311800824 1.0785355413929576 0.8315417884368032 0.8285208206876815 0.05333415124964532 124.79560240194053 164465.84524259664 0.019623175565585568 0.015156679557821146 5.705308103634095e-08 7.243720897416657 -0.24699375295615444 QNT(ph)QSDIGGSGK ddPTM_PC-9_Lapatinib_30min_R1 2 QNTQSDIGGSGK 12 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 QNT(0.993)QS(0.006)DIGGS(0.001)GK;QNT(0.702)QS(0.088)DIGGS(0.21)GK 136.33 0.00015424 3661800.0 37819.0 34408.0 34306.0 30881.0 32132.0 31203.0 31203.0 27659.0 34019.0 24118.0 True False 37279.6941248448 34328.33039002122 31485.49310498957 33152.09175599612 30242.058933942582 29868.520427745636 32818.538662548424 28944.138114143767 30187.421984048688 28286.764164785065 1.3179200670557882 1.2135827975954019 1.1130821794097852 1.1720001468838217 1.0691240170762166 1.0559186004360916 1.1602083034794444 1.0232396305752456 1.0671924794292944 1.0 14.78783953011106 -1.5228787452803376 0.3793468551239784 1.048463662617018 4.809880030290518 0.7829741630770066 0.043086082965636575 30.97718083922933 0.42322805648093254 0.03269361894126198 85.60393900930588 0.029999999999999995 1.5228787452803376 3.7614163676735 QNTASPGSPVNSHLPGS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 QNTASPGSPVNSHLPGSPK 19 0 Q8NDX1-2;Q8NDX1 Q8NDX1-2 PSD4 PH and SEC7 domain-containing protein 4 1 QNTASPGSPVNS(0.004)HLPGS(0.996)PK 87.46799999999999 0.00066532 4059100.0 18951.0 16195.0 25536.0 33561.0 30370.0 27738.0 23040.0 32384.0 24457.0 24030.0 True False 24977.023794712546 21429.71703951396 25197.375955073992 25824.02996228121 26153.649724358987 26003.538475094378 25090.51536560579 27379.796910288624 25749.747090044926 23188.71701416275 1.0771196948696027 0.9241441441725964 1.0866222542491002 1.1136463456132097 1.1278610070744912 1.1213875463317977 1.0820139531773791 1.18073789479453 1.1104429397416855 1.0 14.501135380278994 -5.453187233021711 7.349726615392578 1.1124062912206427 1.000776519402579 0.3547593691900369 0.05501091718293065 0.24527454476661148 22.650042723117654 0.0133585634220629 0.02785519695438416 3.5221898966689825e-06 5.453187233021711 -0.11162977181806366 QNTAWDT(ph)ETSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QNTAWDTETSPR 12 0 Q8NDV7-2;Q8NDV7-6;Q8NDV7-5;Q8NDV7 Q8NDV7-2 TNRC6A Trinucleotide repeat-containing gene 6A protein 1 QNT(0.003)AWDT(0.828)ET(0.084)S(0.084)PR 76.24 0.04614 10193000.0 15998.0 18579.0 24654.0 22269.0 25208.0 25903.0 29199.0 26289.0 26727.0 24767.0 True False 18706.145425097096 20423.400335666534 25241.844860815654 21021.3401270721 20268.673357142103 24544.60108037463 26433.05933754661 25598.94160549795 27117.831812483673 29257.061044535876 0.6393719928540363 0.6980673931868102 0.8627607818294478 0.7185048455507154 0.6927788586245416 0.8389291406615376 0.9034762342434021 0.8749662711005237 0.9268816088944883 1.0 14.836497233461008 -7.261926100287384 0.37107932696022117 1.0126172720675846 0.6653715274919142 0.7402051750578218 0.05806666896394905 0.7754363101109644 0.2623022048196009 0.0748222524205417 0.09555916488292339 5.4710905125600036e-08 7.261926100287384 -0.34724574457567037 QNTAWDTET(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 2 QNTAWDTETSPR 12 0 Q8NDV7-2;Q8NDV7-6;Q8NDV7-5;Q8NDV7 Q8NDV7-2 TNRC6A Trinucleotide repeat-containing gene 6A protein 1 QNTAWDTET(0.5)S(0.5)PR;QNTAWDTET(0.767)S(0.233)PR 149.82 0.00040776 29908000.0 84728.0 82137.0 110032.0 95844.0 108481.0 116605.0 106099.0 128357.0 111077.0 96573.0 True False 111669.74154811891 108686.1789734213 108572.90378636844 73748.64657503879 93420.28566836307 109313.67091673442 115541.60545900206 108522.37500042957 116948.30345181025 93192.00866453325 1.1982759374797967 1.166260718391241 1.165045215166489 0.7913623456761678 1.0024495341081396 1.1729940419058347 1.2398231040916985 1.1645030143204833 1.2549177244670562 1.0 16.507918626764308 -6.8297845212561725 8.527727263224307 1.1818832622710158 1.0608387920594708 0.13420550944899112 0.12610313772343726 0.5477326022460451 61.69536323650561 0.047480169527171115 0.04193190368839894 1.4798424419282765e-07 6.8297845212561725 -0.12104447021154496 QNTAWDTET(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QNTAWDTETSPR 12 0 Q8NDV7-2;Q8NDV7-6;Q8NDV7-5;Q8NDV7 Q8NDV7-2 TNRC6A Trinucleotide repeat-containing gene 6A protein 1 QNTAWDT(0.018)ET(0.673)S(0.309)PR 113.37 0.002059 10797000.0 41588.0 39958.0 40867.0 46582.0 42336.0 34475.0 46231.0 30287.0 32599.0 28805.0 True False 48628.02699955855 43924.766166777736 41841.42426896058 43972.161560881636 34040.564711518906 32667.070310231036 41851.66499654501 29491.998341729108 33075.69870375108 34027.11847974545 1.4290962377112317 1.2908752821054723 1.2296493543485494 1.292268153327645 1.000395162222786 0.9600304630459974 1.229950312174012 0.8667204176952021 0.9720393668784884 1.0 15.05439736420539 -5.6771655171747915 0.5713956724777571 0.9696289312116524 1.4844054339637183 0.6874469552068556 0.09975207839652923 0.9793661539007649 0.481389673002076 0.06540984143130611 0.29760778760149154 2.102976806008846e-06 5.6771655171747915 0.5147765027520659 QNTAWDTETS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QNTAWDTETSPR 12 0 Q8NDV7-2;Q8NDV7-6;Q8NDV7-5;Q8NDV7 Q8NDV7-2 TNRC6A Trinucleotide repeat-containing gene 6A protein 1 QNTAWDTET(0.1)S(0.9)PR 155.14 0.00030365 9013200.0 42399.0 58324.0 57783.0 44196.0 56284.0 41534.0 61480.0 39084.0 40081.0 35167.0 True False 49576.313281578434 64114.02127011223 59160.76586324784 41719.84140536527 45255.55423807467 39355.88392357177 55656.1693233455 38058.08641292107 40667.10879919772 41542.49871818116 1.1933878512676288 1.5433356983423965 1.4241022492312436 1.0042689460830745 1.0893796866934362 0.9473643891898968 1.3397405317602493 0.9161241520665888 0.9789278462780496 1.0 15.342300374256615 -5.759398601384329 24.995434163625458 1.0466677055048803 1.4025813884635112 0.5742724690904859 0.13682831872864717 36.63633659334309 448707.3851852831 0.03700053094802261 0.060223672408301135 1.7402089527537055e-06 5.759398601384329 0.3559136829586309 QNTAWDTETS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 QNTAWDTETSPR 12 0 Q8NDV7-2;Q8NDV7-6;Q8NDV7-5;Q8NDV7 Q8NDV7-2 TNRC6A Trinucleotide repeat-containing gene 6A protein 1 QNTAWDT(0.001)ET(0.104)S(0.895)PR;QNTAWDTET(0.047)S(0.953)PR 128.95 0.00018969 38835000.0 76586.0 93029.0 90630.0 77785.0 105232.0 101928.0 91278.0 92410.0 98384.0 79795.0 True False 75493.86959584785 92813.59706618478 83178.75124191711 83505.56838315348 99042.4606540722 97568.77704577298 96003.92821331599 96703.70595929088 87302.95789055074 93587.45942984588 0.8066665133958341 0.991731131837795 0.8887809515148635 0.8922730555128501 1.0582877370265131 1.0425411442962775 1.0258204336156973 1.033297693392147 0.9328488926018333 1.0 16.51402760347692 -6.252187650030583 24.658566384644452 1.0190023489331763 0.9013476369849505 0.5575774586458018 0.052445906630862765 425.5489344545934 1134211.456819195 0.015160061487938779 0.019280836062047283 5.595157935833109e-07 6.252187650030583 -0.11765471194822585 QNTQSDIGGS(ph)GK ddPTM_PC-9_Lapatinib_30min_R1 1 QNTQSDIGGSGK 12 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 QNT(0.304)QS(0.019)DIGGS(0.677)GK 132.24 0.00073992 0.0 17397.0 13475.0 14666.0 13418.0 17877.0 14597.0 13812.0 11320.0 13154.0 12084.0 True False 17148.91558978092 13443.79946540154 13460.218092397161 14404.804481135843 16825.51000753429 13972.720337268956 14527.11777736496 11845.968525691726 11672.458002239237 14172.703299082114 1.2099960909286487 0.948569879838818 0.949728348103421 1.0163766345174785 1.1871771850768924 0.9858895683065553 1.0250068367906777 0.8358298537484322 0.8235872688448361 1.0 13.790827343465933 -7.713309721735788 6.791266102236181 0.8724622577279494 1.0413493691487579 0.3682788671276065 0.09519144817433785 0.20277332751910782 21.755207599217535 0.046029328990529146 0.025953024256523318 1.935041476309876e-08 7.713309721735788 0.16888711142080848 QNVPSGGPVPS(ph)PQTYR ddPTM_PC-9_AZD4547_30min_R2 1 QNVPSGGPVPSPQTYR 16 0 Q5JSZ5;A0A494C0D3;Q5JSZ5-5;A0A494C065;H3BLU0;Q5JSZ5-4;Q5JSZ5-2;Q5JSZ5-3 Q5JSZ5 PRRC2B Protein PRRC2B 1 QNVPSGGPVPS(0.753)PQT(0.247)YR 103.39 0.0013705 4864300.0 18989.0 17550.0 17044.0 33768.0 27698.0 19622.0 21236.0 20434.0 19022.0 21533.0 True False 25027.107004263427 23222.69429104477 16817.985423648242 25983.30931039933 23852.610802281677 18395.033238095813 23125.962860416887 17276.3948266069 20027.46408581734 20779.136224135116 1.2044344256809993 1.1175967104961486 0.809368842007688 1.2504518489185095 1.1479115659570438 0.8852645769139262 1.1129414914541016 0.8314298842961644 0.9638256311422271 1.0 14.342848063095833 -6.755751960748602 24.998946886450874 0.9577972553593386 1.0981504264196793 0.2430768870339366 0.12956003633643812 226.61670126077536 996089.0022912693 0.0439812125253548 0.0428285825386156 1.754882484317972e-07 6.755751960748602 0.14035317106034073 QNVPSGGPVPS(ph)PQTYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QNVPSGGPVPSPQTYR 16 0 Q5JSZ5;A0A494C0D3;Q5JSZ5-5;A0A494C065;H3BLU0;Q5JSZ5-4;Q5JSZ5-2;Q5JSZ5-3 Q5JSZ5 PRRC2B Protein PRRC2B 1 QNVPS(0.001)GGPVPS(0.906)PQT(0.094)YR 129.36 1.7653e-05 3632400.0 8055.5 11169.0 10763.0 11319.0 17006.0 12732.0 13367.0 11422.0 10985.0 9477.9 True False 9419.137046622676 12277.7845066505 11019.630738904802 10684.833126693124 13673.796378592457 12064.311506594979 12100.78099130058 11122.184602609359 11145.634843421753 11196.16824298488 0.8412821996064923 1.0966059316180177 0.9842323283958607 0.9543294540422665 1.2212925066716436 1.0775393192357614 1.0807966376248854 0.9933920571065126 0.9954865451763115 1.0 13.45071745087769 -4.75301983756345 24.993562293596398 1.0475814586354826 0.8412818138092024 0.4027769038133754 0.0742987734670747 340.14505585149766 1009649.4761837204 0.019186528323387853 0.21568655864457942 1.7659571540218125e-05 4.75301983756345 -0.20629964482628016 QNVPSGGPVPS(ph)PQTYR ddPTM_PC-9_Lapatinib_30min_R1 1 QNVPSGGPVPSPQTYR 16 0 Q5JSZ5;A0A494C0D3;Q5JSZ5-5;A0A494C065;H3BLU0;Q5JSZ5-4;Q5JSZ5-2;Q5JSZ5-3 Q5JSZ5 PRRC2B Protein PRRC2B 1 QNVPSGGPVPS(0.5)PQT(0.5)YR 167.35 4.575800000000001e-21 0.0 14546.0 10205.0 14719.0 11623.0 13367.0 14964.0 13107.0 13991.0 13720.0 11457.0 True False 14338.571372590293 10181.370949493337 13508.860636983078 12477.794193191377 12580.779340533138 14324.024602787744 13785.616326956459 14641.072936656627 12174.709121995005 13437.327184507114 1.067070197495994 0.7576931639524407 1.0053234881828612 0.9285919753132116 0.9362560848439001 1.0659876332625857 1.0259195253391546 1.0895822313188444 0.9060365171454726 1.0 13.713958580081664 -6.737335191543449 20.202442636980102 1.0236297553881872 0.9320224328960696 0.16731141434998953 0.08635220236039894 40.931217057993614 34304.183087001904 0.026922907861669794 0.026885253168759823 1.8309007747816918e-07 6.737335191543449 -0.09160732249211767 QNVPSGGPVPSPQT(ph)YR ddPTM_PC-9_AZD4547_30min_R2 1 QNVPSGGPVPSPQTYR 16 0 Q5JSZ5;A0A494C0D3;Q5JSZ5-5;A0A494C065;H3BLU0;Q5JSZ5-4;Q5JSZ5-2;Q5JSZ5-3 Q5JSZ5 PRRC2B Protein PRRC2B 1 QNVPSGGPVPS(0.132)PQT(0.868)YR 135.69 2.0439000000000002e-05 5078300.0 25462.0 26388.0 34763.0 42172.0 42200.0 31950.0 28043.0 38724.0 30929.0 30647.0 True False 33558.38635749939 34917.404954535006 34302.019906259324 32449.896950905008 36341.25842502299 29952.161449248862 30538.77267351059 32740.09558899508 32563.843797195055 29574.057858220796 1.1347237676472948 1.1806768324431645 1.159868560165283 1.0972419512557627 1.2288221859592088 1.0127849750223898 1.032620305942278 1.1070545593016823 1.10109488367499 1.0 14.852044588860993 -6.771067822138909 24.999999717340895 1.0562711890525074 1.1578770731784145 0.5988829145661098 0.044693063712586516 155.0882701380368 402680.03503879526 0.015747571182620067 0.014063060568896345 1.6940732227331218e-07 6.771067822138909 0.1016058841259071 QNVSTSNS(ph)GSMPNLAQK ddPTM_PC-9_Lapatinib_30min_R1 1 QNVSTSNSGSMPNLAQK 17 0 Q9Y2L6;E9PGA7;Q9Y2L6-2 Q9Y2L6 FRMD4B FERM domain-containing protein 4B 1 QNVSTS(0.005)NS(0.908)GS(0.087)MPNLAQK 118.66 0.00097154 0.0 15982.0 14533.0 13595.0 12680.0 12480.0 17574.0 11335.0 12394.0 12642.0 8570.5 True False 15754.093749260152 14499.34973140486 12477.2715782176 13612.529499240005 11745.950936624036 16822.400986994897 11921.870837419043 12969.870486521486 11218.124833838247 10051.899505526584 1.5672752936495706 1.4424487355283493 1.2412849503079029 1.3542245912581765 1.168530478260955 1.673554433940158 1.1860316381858313 1.2902905047340143 1.1160203927297985 1.0 13.295180532521805 -12.043074990095436 0.06493869379487592 2.5198211584637555e-10 1.9262520830084455 0.44161898034337177 0.14789431363238958 204.01192876325442 1.606126651984423 42.10649347293795 12.587098204309415 9.05576220577118e-13 12.043074990095436 1.9262520827564633 QNVSTSNSGS(ph)MPNLAQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QNVSTSNSGSMPNLAQK 17 0 Q9Y2L6;E9PGA7;Q9Y2L6-2 Q9Y2L6 FRMD4B FERM domain-containing protein 4B 1 QNVSTSNS(0.004)GS(0.996)MPNLAQK 125.98 5.4243e-05 0.0 7086.6 9495.8 11071.0 12988.0 16034.0 11717.0 11359.0 7915.0 9882.1 10609.0 True False 8286.22141326997 10438.480268444075 11334.974627001302 12260.324467664137 12892.25280103207 11102.539893400359 10282.993287961644 7707.239636635713 10026.607017403556 12532.32771920221 0.6611877377395505 0.8329242980496023 0.9044588428400011 0.9782958714747535 1.0287197310742502 0.8859120302439019 0.8205174264798307 0.6149886764313202 0.8000594336549822 1.0 13.613366781205235 -7.4004691636111195 4.378534894141935 0.7707084687085348 0.8912330758624395 0.049161691520105855 0.12699579197880484 0.4630312077966698 14.363941436185371 0.0576789209553539 0.037558754766475175 3.976773319185379e-08 7.4004691636111195 0.12052460715390467 QNVSTSNSGS(ph)MPNLAQK ddPTM_PC-9_Lapatinib_30min_R1 1 QNVSTSNSGSMPNLAQK 17 0 Q9Y2L6;E9PGA7;Q9Y2L6-2 Q9Y2L6 FRMD4B FERM domain-containing protein 4B 1 QNVSTS(0.008)NS(0.229)GS(0.763)MPNLAQK 102.36 0.0070972 0.0 12190.0 9700.7 12193.0 11383.0 11514.0 11654.0 10616.0 10829.0 11916.0 9835.3 True False 12016.168364627783 9678.238625159236 11190.538606341097 12220.143792574845 10836.769157394969 11155.585586800878 11165.64453551306 11332.154873208101 10573.894598957175 11535.31850028652 1.0416850097662513 0.8390092241422588 0.9701109341769056 1.059367696892922 0.9394425613064606 0.9670808470978752 0.9679528601863678 0.9823876881185923 0.9166538920181992 1.0 13.493770218198888 -5.4911010468624255 24.95278262250338 0.976346144981713 0.9314003645064108 0.05225505775346051 0.05767906163158449 1503.6539367278792 1180710.4389940256 0.014342170853507731 0.029807360309743382 3.2277430385969554e-06 5.4911010468624255 -0.04494578047530218 QNY(ph)KY(ph)DK ddPTM_PC-9_AZD4547_30min_R2 1 QNYKYDK 7 1 O14495 O14495 PPAP2B Lipid phosphate phosphohydrolase 3 2 QNY(1)KY(1)DK 62.717 0.037725 4503300.0 5688.9 12204.0 11441.0 29261.0 22010.0 22538.0 15665.0 23936.0 20707.0 19015.0 True False 7497.8518635291075 16148.704337772659 11289.284864583395 22515.32852794344 18954.291420254893 21128.695297125858 17059.1546528739 20237.241194561164 21801.529745821666 18349.290637715552 0.4086180774813088 0.8800724047925995 0.6152436673153533 1.2270408144097362 1.0329713444777973 1.1514720494806188 0.9296901438691109 1.102889566366401 1.1881401944231187 1.0 14.163436670779719 -4.661996489358081 0.7822005352454819 1.0898918964991182 5.626237504771798e-13 0.6509156874938136 0.14677675551894692 1.897643429422054 0.7821408382750354 0.05473996035061138 1.889344317418405 2.177727376053947e-05 4.661996489358081 -1.0898918964985556 QPAQELS(ph)PTPGGTAHQALK ddPTM_PC-9_AZD4547_30min_R2 1 QPAQELSPTPGGTAHQALK 19 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 QPAQELS(0.65)PT(0.346)PGGT(0.004)AHQALK 196.36 8.1848e-15 7756900.0 24745.0 20805.0 20555.0 28922.0 24456.0 31916.0 22176.0 29556.0 20715.0 22839.0 True False 32613.39527202583 27529.80938605048 20282.42726960159 22254.479740445648 21060.706541288215 29920.287474623692 24149.62103939559 24988.799329313566 21809.952609489334 22039.413561650577 1.479776001334917 1.2491171468352227 0.9202798074851588 1.0097582532399725 0.9555928737566162 1.357580926140709 1.0957469885413311 1.1338232416852976 0.9895886089927314 1.0 14.427798215847153 -4.938685426273272 3.571301279117209 1.0691870210773455 1.4736660161847461 0.554163843224387 0.11828162787714093 0.19297955856730525 4.694379745646713 0.03155669326729774 0.16691824749701434 1.1516342533434614e-05 4.938685426273272 0.4044789951074006 QPAQELS(ph)PTPGGTAHQALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QPAQELSPTPGGTAHQALK 19 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 QPAQELS(0.99)PT(0.01)PGGTAHQALK;QPAQELS(0.992)PT(0.008)PGGTAHQALK;QPAQELS(0.999)PT(0.001)PGGTAHQALK 128.95 2.0171e-05 77651900.0 179752.0 190960.0 202128.0 204185.0 253360.0 225653.0 231558.0 188013.0 191403.0 177910.0 True False 210180.4633361701 209917.24678932573 206947.49809470892 192745.17642670134 203715.92675997788 213819.3594405967 209623.14990525777 183077.85796623974 194201.90677609926 210163.67466521537 1.000079883790486 0.9988274478152221 0.9846968008356833 0.9171193677201296 0.9693203503625992 1.017394465438448 0.9974280771364574 0.8711203696731962 0.9240507765457435 1.0 17.681153805444175 -7.735937734182933 24.997063364902676 0.9231891196376516 0.9823829945646718 0.26409919181500685 0.0388367137764082 257.1114604228199 252024.47191504188 0.018614317979101163 0.010742038377252001 1.8368016710286408e-08 7.735937734182933 0.05919387492702022 QPAQELSPT(ph)PGGTAHQALK ddPTM_PC-9_Lapatinib_30min_R1 1 QPAQELSPTPGGTAHQALK 19 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 QPAQELS(0.356)PT(0.568)PGGT(0.076)AHQALK 90.581 0.0024173000000000003 7537700.0 25541.0 21612.0 22282.0 23203.0 24608.0 23318.0 23017.0 26461.0 21589.0 23737.0 True False 25176.780656354225 21561.958741837334 20450.059971007344 24909.42602293895 23160.605821189452 22320.7434969129 24208.707636954066 27690.474660629767 19157.419477751475 27839.908822435653 0.9043413474136358 0.7744981809876101 0.7345591575546767 0.8947380604517253 0.8319210371308674 0.8017534697859727 0.8695684957647825 0.9946323760340242 0.6881279532895911 1.0 14.764866865821029 -14.522878745277497 0.24114598871319032 1.9291211277263292 0.8192018799536277 0.23406110160952853 0.08603362084578287 248.92149103069474 2.476474775323105 113.80606235955152 0.1303669716516886 3.000000000019622e-15 14.522878745277497 -1.1099192477727016 QPAQELSPTPGGT(ph)AHQALK ddPTM_PC-9_Lapatinib_30min_R1 1 QPAQELSPTPGGTAHQALK 19 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 QPAQELS(0.101)PT(0.162)PGGT(0.737)AHQALK 107.03 0.0005141 8088000.0 25183.0 26258.0 26608.0 22136.0 26228.0 27122.0 21293.0 24146.0 23699.0 18617.0 True False 24823.88580200341 26197.20121428671 24420.39294985024 23763.9552835313 24685.32060623199 25962.05528447 22395.447352550844 25267.911309306764 21029.76905846645 21834.923644406797 1.1368890593012109 1.199784420633747 1.1184098166565255 1.0883461591411903 1.1305430240217647 1.189015162465219 1.025670971754812 1.1572246242216357 0.963125376619002 1.0 14.414349865646859 -8.263586549860543 24.999787191837868 0.9815626696714937 1.1296473105031137 0.6118520338045683 0.047518972779813685 127.9951196324721 1490208.847051239 0.03890820550638543 0.011954173891346523 5.450212684384558e-09 8.263586549860543 0.14808464083161998 QPAQS(ph)QNLSPLSGFSR ddPTM_PC-9_Lapatinib_30min_R1 1 QPAQSQNLSPLSGFSR 16 0 Q9P2M7-2;Q9P2M7;A6PVU7 Q9P2M7-2 CGN Cingulin 1 QPAQS(0.436)QNLS(0.298)PLS(0.26)GFS(0.006)R 83.25200000000001 0.0056739 14945000.0 11049.0 11738.0 14687.0 14949.0 8471.7 11091.0 11304.0 12207.0 15533.0 9258.6 True False 10891.439233861558 11710.821382180573 13479.49155345951 16048.399328402124 7973.411262003032 10616.663784383778 11889.265809103215 12774.181783844433 13783.509970258625 10858.936673690976 1.0029931623277009 1.0784501037337793 1.2413270247829709 1.4778978652011272 0.734271826202008 0.9776890779836505 1.0948830595824839 1.1763750142123686 1.2693240953926275 1.0 13.406595218354786 -11.937785930338425 2.195741174900983 0.055640266708775164 1.1158978652639107 0.03367888018733034 0.1879641215057302 2926759.7017286154 852749.3176762003 13752052.501930073 0.050619691179772004 1.1540219507789582e-12 11.937785930338425 1.0602575985551355 QPAQSQNLS(ph)PLSGFSR ddPTM_PC-9_AZD4547_30min_R2 4 QPAQSQNLSPLSGFSR 16 0 Q9P2M7-2;Q9P2M7;A6PVU7 Q9P2M7-2 CGN Cingulin 1 QPAQS(0.001)QNLS(0.96)PLS(0.029)GFS(0.01)R;QPAQSQNLS(0.992)PLS(0.008)GFSR;QPAQS(0.002)QNLS(0.997)PLS(0.001)GFSR;QPAQS(0.006)QNLS(0.972)PLS(0.021)GFSR 199.05 4.3398e-12 84620000.0 37354.8 28532.899999999994 35860.5 49953.6 47990.1 40901.0 39746.399999999994 49986.6 35387.5 34638.299999999996 True False 49232.84937189216 37755.60193372939 35384.96633916555 38437.56929542653 41327.50298442406 38343.45400424812 43283.7526010206 42262.31954779625 37258.011004986925 33425.623660077974 1.4729074279231358 1.1295406876378777 1.0586179841852204 1.1499432197980077 1.2364018516065485 1.1471275568163526 1.294927300121455 1.2643689158228757 1.1146541762057287 1.0 15.02866685813009 -8.539695640501831 4.617195356096315 1.0001632326753909 1.2087681763519598 0.2886533331594998 0.10826195451625764 0.2321031886894441 18.631332963371843 0.10543090165426243 0.027485443812425934 2.8860533801487264e-09 8.539695640501831 0.2086049436765689 QPAQSQNLS(ph)PLSGFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QPAQSQNLSPLSGFSR 16 0 Q9P2M7-2;Q9P2M7;A6PVU7 Q9P2M7-2 CGN Cingulin 1 QPAQSQNLS(0.991)PLS(0.009)GFSR;QPAQSQNLS(0.919)PLS(0.081)GFSR;QPAQS(0.071)QNLS(0.885)PLS(0.043)GFS(0.001)R 202.79 2.2321999999999998e-13 50381000.0 34161.7 29372.0 44476.0 39051.2 49116.8 43126.9 42804.5 33095.7 39400.0 33635.6 True False 39944.60108566942 32287.85804721448 45536.4765161693 36863.28786969859 39492.715627898964 40865.24944343155 38749.7478822567 32226.972942792716 39976.15046252315 39733.46802073689 1.0053137336218008 0.8126111224513162 1.1460483764569411 0.9277641672370419 0.9939408160215898 1.0284843352234945 0.975242026747658 0.8110787844135192 1.0061077588711764 1.0 15.278067099931498 QPAQSQNLS(ph)PLSGFSR ddPTM_PC-9_Lapatinib_30min_R1 1 QPAQSQNLSPLSGFSR 16 0 Q9P2M7-2;Q9P2M7;A6PVU7 Q9P2M7-2 CGN Cingulin 1 QPAQS(0.002)QNLS(0.997)PLS(0.002)GFSR 234.82 5.9623999999999996e-37 20538000.0 13001.0 10190.0 11118.0 8058.7 12094.0 8663.5 10821.0 10797.0 12866.0 8936.9 True False 12815.603355908595 10166.40568107173 10203.9209567211 8651.363681035127 11382.654697718845 8292.982300604886 11381.258432440362 11298.66803638636 11416.895595013684 10481.631257329282 1.2226726013612894 0.969925904802544 0.9735050495681201 0.8253833271405785 1.085962138742433 0.7911919525699798 1.0858289280575497 1.077949391559235 1.0892288914505 1.0 13.355575640672846 QPAQSQNLSPLS(ph)GFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QPAQSQNLSPLSGFSR 16 0 Q9P2M7-2;Q9P2M7;A6PVU7 Q9P2M7-2 CGN Cingulin 1 QPAQSQNLS(0.385)PLS(0.509)GFS(0.106)R 140.68 2.1672e-05 16196000.0 20287.0 20338.0 19801.0 18252.0 19494.0 21695.0 21054.0 17179.0 18090.0 15824.0 True False 23721.188413485732 22357.022230840543 20273.130935710666 17229.399613782403 15674.290638849909 20557.276008135235 19059.61270224003 16728.069452655072 18354.532027082336 18692.765937284912 1.2690036612597306 1.196025366489335 1.0845442030209949 0.9217148319081205 0.8385217410541529 1.0997450070848713 1.019625065984665 0.8948953573151514 0.981905625345261 1.0 14.190192437597908 -5.378430755186728 2.2986064674204165 0.9641625113341447 1.2494720828580566 0.7024526306990595 0.06953233915991736 0.17850309518524404 1.7920360540729348 0.020601116801234862 0.05991145437267238 4.183783904524456e-06 5.378430755186728 0.2853095715239119 QPAQSQNLSPLS(ph)GFSR ddPTM_PC-9_Lapatinib_30min_R1 2 QPAQSQNLSPLSGFSR 16 0 Q9P2M7-2;Q9P2M7;A6PVU7 Q9P2M7-2 CGN Cingulin 1 QPAQS(0.06)QNLS(0.104)PLS(0.783)GFS(0.052)R;QPAQSQNLS(0.31)PLS(0.67)GFS(0.02)R 172.93 1.6170999999999998e-05 32965000.0 29037.0 22024.7 24237.1 18425.6 24321.5 23608.6 20489.0 19376.3 22702.0 16233.599999999999 True False 28622.927055266344 21973.703160343546 22244.419195911574 19780.680089999732 22890.95718790879 22598.915212334578 21549.820166553054 20276.593634660843 20145.061697341887 19039.55613008767 1.5033400390061797 1.1541079534737224 1.1683265641240108 1.0389254851766678 1.2022841830716242 1.1869454864350621 1.1318446721821673 1.064971971831755 1.058063620795614 1.0 14.21671222498177 -4.691627269377501 2.7408056216340118 1.11428475725935 1.639770068372044 0.7724812924975565 0.06402005393324976 0.32662967200194265 2.597598940958013 0.0167113400682924 0.43368145715346224 2.0341020178097512e-05 4.691627269377501 0.525485311112694 QPASAQSTPSTTPHS(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 1 QPASAQSTPSTTPHSSPK 18 0 A0A087WT18;Q96A73-2;Q96A73 A0A087WT18 KIAA1191 Putative monooxygenase p33MONOX 1 QPASAQSTPSTTPHS(0.5)S(0.5)PK 138.46 1.3333e-08 0.0 7165.1 4418.2 9408.5 4789.0 7104.8 9677.1 7182.3 8862.1 9931.3 4784.8 True False 7062.924360081585 4407.969929353397 8634.969447860263 5141.199035635675 6686.909632574239 9263.232991421897 7554.1643507362005 9273.865518686634 8812.732412774703 5611.846304654763 1.258574090709366 0.7854758826337052 1.5387038381108125 0.9161332574934012 1.1915703441535386 1.6506569297413722 1.3461103424144698 1.6525515873437941 1.570380216126902 1.0 12.454259782117981 -6.626030967096034 6.565672586172607 1.47714556215627 1.1211325910752106 0.2587178918671057 0.2574622937418557 0.2591535554000326 14.436154796336567 0.08022280143751988 0.0801014571590029 2.3657510030779e-07 6.626030967096034 -0.35601297108105934 QPASAQSTPSTTPHSS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 QPASAQSTPSTTPHSSPK 18 0 A0A087WT18;Q96A73-2;Q96A73 A0A087WT18 KIAA1191 Putative monooxygenase p33MONOX 1 QPASAQSTPSTTPHS(0.227)S(0.773)PK;QPASAQSTPSTTPHS(0.251)S(0.749)PK 136.11 1.7858e-08 0.0 11021.2 7840.2 21806.0 40609.0 35177.0 35006.0 19234.1 26595.0 17155.2 23763.0 True False 14525.712344798992 10374.391326532717 21516.83819221272 31247.22245279571 30293.280749218822 32817.06928614728 20945.897638611048 22485.353842302553 18061.988848965077 22931.064602894272 0.6334512852475943 0.45241647111418026 0.9383270495647614 1.3626590389027033 1.3210586282764787 1.4311184349463317 0.9134289227883182 0.9805630149183975 0.787664644522669 1.0 14.485015714915717 -5.41962370140522 4.239648641539857 1.1283190671350902 0.5497002621890826 0.5542292292746516 0.2012103645025396 0.17296622736470296 5.248996699870052 0.059299629204156296 0.12945760958251323 3.805189578032804e-06 5.41962370140522 -0.5786188049460076 QPCPS(ph)ESDIITEEDK ddPTM_PC-9_AZD4547_30min_R2 1 QPCPSESDIITEEDK 15 0 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 QPCPS(0.873)ES(0.089)DIIT(0.038)EEDK 114.99 0.0023603 0.0 3159.8 4175.0 3972.0 3150.0 4546.0 5394.9 4465.3 5357.8 4244.4 4106.3 True False 4164.550672077077 5524.487103425178 3919.3286847413033 2423.8161670148615 3914.866369671912 5057.556050158146 4862.703049567691 4529.875119995809 4468.750318885664 3962.539686860447 1.050980179677818 1.3941783653912814 0.9890951244570675 0.6116824962162767 0.9879689994407835 1.276342055810497 1.2271682894917453 1.1431747005630286 1.127749037745611 1.0 11.95220966931477 -6.7393730610469165 24.67043783443666 1.1683528423938552 1.005370574835965 0.1320063727870524 0.188296573445486 449.8554096834462 502942.82450521336 0.06875842904709595 0.06870218369404438 1.8223296398706678e-07 6.7393730610469165 -0.16298226755789025 QPCPS(ph)ESDIITEEDKSK ddPTM_PC-9_AZD4547_30min_R2 1 QPCPSESDIITEEDKSK 17 1 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 QPCPS(0.903)ES(0.097)DIITEEDKSK 81.574 0.0023647 13923000.0 38709.0 34731.0 38720.0 49157.0 48581.0 46014.0 45899.0 38175.0 43421.0 43893.0 True False 51017.65680278231 45957.116548277816 38206.547500801425 37824.6131180792 41836.36671910056 43136.737305969895 49983.92208185505 32275.930924230128 45716.145414271625 42356.31942998942 1.2044874882745462 1.0850120399209884 0.9020270886367469 0.8930099127380353 0.9877243179321026 1.0184250635202245 1.1800818096216614 0.7620098100728246 1.0793228974919704 1.0 15.370289610739945 -4.971530158956614 3.661506215565972 0.9755291641693025 1.1967180279149945 0.30999465231723045 0.10659811844180812 0.27310233921058863 7.600928515354138 0.02696401188701152 0.12700412023636537 1.0677506415545477e-05 4.971530158956614 0.22118886374569202 QPCPS(ph)ESDIITEEDKSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QPCPSESDIITEEDKSK 17 1 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 QPCPS(0.748)ES(0.252)DIITEEDKSK;QPCPS(0.918)ES(0.082)DIITEEDKSK 99.711 0.00058079 11847800.0 41039.0 51549.0 45761.0 53200.0 66950.0 63404.0 78987.0 73576.0 66985.0 63184.0 True False 47986.09214280279 56666.44404452744 46852.11578955895 50219.37647672711 53831.6281045963 60078.98262363711 71504.7795436417 71644.70796021594 67964.52890183014 74638.75903573124 0.6429111732663022 0.7592093541828575 0.6277183114356147 0.6728324147603523 0.7212288735779475 0.8049300845808001 0.9580113665798055 0.9598861085822449 0.9105795672365614 1.0 16.187637379299147 -6.999233177812803 1.8977717126104903 0.9582631743609534 0.679844344257234 0.914303470033111 0.039368116615971116 0.09130584891917351 0.6616680985943876 0.017518492591988576 0.013494358591195507 1.0017672330562336e-07 6.999233177812803 -0.2784188301037195 QPCPS(ph)ESDIITEEDKSK ddPTM_PC-9_Lapatinib_30min_R1 2 QPCPSESDIITEEDKSK 17 1 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 QPCPS(0.945)ES(0.055)DIITEEDKSK;QPCPS(0.996)ES(0.004)DIITEEDKSK 80.488 0.0026951 25610000.0 64129.0 65451.0 74717.0 69235.0 88074.0 74683.0 85097.0 99360.0 102041.0 78647.0 True False 63214.5087001817 65299.45223079748 68574.05667596078 74326.77286118956 82893.66048014621 71488.98218457605 89502.90627718123 103976.62833151316 90548.06804063363 92241.02915945991 0.6853187705755194 0.7079219825042531 0.7434225019043824 0.8057886337401827 0.898663655810316 0.7750236834520876 0.9703155644811248 1.1272275394040276 0.981646333152901 1.0 16.49312098918881 -6.784858285838816 0.6646822834461614 1.054087007170728 0.6948707932365551 0.7881607112460423 0.06442907963837412 0.3443884168109445 0.3327826846399284 0.05209795352249975 0.053594158569598115 1.641125199620864e-07 6.784858285838816 -0.3592162139341729 QPDISCILGTGGKS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QPDISCILGTGGKSPR 16 1 G3V1T4;P57740;P57740-2 G3V1T4 NUP107 Nuclear pore complex protein Nup107 1 QPDIS(0.003)CILGT(0.086)GGKS(0.911)PR;QPDISCILGT(0.036)GGKS(0.963)PR 114.9 0.0008942 16156900.0 21317.9 20200.5 21500.3 27873.0 28910.0 28378.0 32144.0 27367.0 27492.0 21300.0 True False 24926.59942228261 22205.872139546387 22012.948692341804 26311.36617548523 23245.293032171463 26889.807723386137 29099.087617593 26648.64524773334 27894.018490245846 25161.521389292768 0.9906634434629168 0.882532967541298 0.8748655676166384 1.0456985397823269 0.9238429057021673 1.0686876722338747 1.1564915796377806 1.0591030977591602 1.1085982464524529 1.0 14.61893153683936 -6.813437720064646 5.542123470812827 1.0889566787025609 0.941898795983213 0.5607589052082882 0.059539485830317235 0.14054865773190192 9.282188834879538 0.02102621872420832 0.01879036749998408 1.5366051341621587e-07 6.813437720064646 -0.14705788271934783 QPDISCILGTGGKS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 QPDISCILGTGGKSPR 16 1 G3V1T4;P57740;P57740-2 G3V1T4 NUP107 Nuclear pore complex protein Nup107 1 QPDISCILGTGGKS(1)PR;QPDIS(0.132)CILGT(0.223)GGKS(0.645)PR 174.7 6.0202e-05 16026500.0 36713.0 30041.0 35154.0 32088.0 36893.0 39716.0 34981.0 34270.0 43600.0 35601.0 True False 36189.46588766034 29971.441910213547 32263.773818364243 34447.85856243008 34723.02627442875 38017.43926251792 36792.14501665244 35862.309308785814 38689.30887164592 41754.58541464933 0.866718362265513 0.7178000119646323 0.7727001357566995 0.8250077978344451 0.8315979174408565 0.9104973474165964 0.8811522052316714 0.8588831370890286 0.9265882653949672 1.0 15.34964702005155 -7.552783504305782 0.2810517175036752 1.0133887718217456 0.7445819590456659 0.6761753304694127 0.042941225223237706 1.0818660164887914 0.2866738147531075 0.0834373562096953 0.10796818908885514 2.8003769589794547e-08 7.552783504305782 -0.26880681277607965 QPDS(ph)LSSIENAVK ddPTM_PC-9_AZD4547_30min_R2 1 QPDSLSSIENAVK 13 0 Q9BZV3 Q9BZV3 IMPG2 Interphotoreceptor matrix proteoglycan 2 1 QPDS(0.989)LS(0.008)S(0.003)IENAVK 65.809 0.038891 14661000.0 14031.0 18111.0 35144.0 66073.0 46810.0 30805.0 20086.0 46369.0 23253.0 31597.0 True False 18492.5661370699 23965.02657009182 34677.96759731833 50840.89066767396 40311.239499415344 28878.75848025389 21873.615088262086 39203.73650361824 24482.10610805963 30490.798647378288 0.6064966139763598 0.7859756921176095 1.1373256567781007 1.6674174807830247 1.3220788332115878 0.947130274094575 0.717384130905435 1.2857563016634568 0.8029342357080139 1.0 14.89608631899262 QPEDDSSQAFIS(ph)TQNGSPR ddPTM_PC-9_Lapatinib_30min_R1 1 QPEDDSSQAFISTQNGSPR 19 0 Q5TCQ9-3;Q5TCQ9-2;Q5TCQ9;Q5TCQ9-1 Q5TCQ9-3 MAGI3 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 1 QPEDDSSQAFIS(0.83)T(0.066)QNGS(0.104)PR 151.28 6.7134e-05 15906000.0 16069.0 16038.0 16816.0 11400.0 13960.0 14646.0 13938.0 13702.0 14789.0 13440.0 True False 15839.853113306306 16000.864996371787 15433.453391637155 12238.394029285182 13138.900246415991 14019.624721493525 14659.641440842228 14338.644941610255 13123.30708492595 15763.086092325704 1.004870050225633 1.0150845400864648 0.9790883143847681 0.7763958121908294 0.8335233449503708 0.8893959367714811 0.9299981840471777 0.9096343734740533 0.832534124857382 1.0 13.944262392404116 -5.550180162560646 20.57704878054078 0.8781719296859462 1.0067546559478495 0.47331059810595333 0.05757736131054017 23.71509501181378 17873.521253831794 0.01574938261225462 0.027282330555863765 2.817213996818958e-06 5.550180162560646 0.12858272626190337 QPEDDSSQAFISTQNGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 QPEDDSSQAFISTQNGSPR 19 0 Q5TCQ9-3;Q5TCQ9-2;Q5TCQ9;Q5TCQ9-1 Q5TCQ9-3 MAGI3 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 1 QPEDDSSQAFIS(0.001)T(0.004)QNGS(0.995)PR;QPEDDSSQAFIS(0.023)T(0.023)QNGS(0.954)PR 200.14 3.5264000000000003e-15 28706000.0 18858.3 14185.9 17351.0 24489.3 21066.7 22812.6 18688.9 24136.9 20866.9 21228.3 True False 24854.847122992327 18771.2147546058 17120.914403058003 18843.67024091335 18141.95234271167 21386.124515716256 20352.17589480341 20407.096715783897 21969.88173337933 20485.103678391646 1.213313220826411 0.9163348669992961 0.8357738711919579 0.9198718511144401 0.8856168183248392 1.0439841970765829 0.9935110026448901 0.9961920152403215 1.0724808660135743 1.0 14.322287574096878 -6.777840238339319 24.976358693355003 1.019262959402986 0.9435951259922916 0.1018036857172463 0.09697961959932228 548.1392523805882 834738.8155327642 0.03496074364162969 0.030921420905847007 1.667860646967547e-07 6.777840238339319 -0.0756678334106945 QPEDDSSQAFISTQNGS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 QPEDDSSQAFISTQNGSPR 19 0 Q5TCQ9-3;Q5TCQ9-2;Q5TCQ9;Q5TCQ9-1 Q5TCQ9-3 MAGI3 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 1 QPEDDSSQAFIS(0.005)T(0.09)QNGS(0.905)PR;QPEDDSSQAFISTQNGS(1)PR;QPEDDSSQAFIS(0.007)T(0.004)QNGS(0.989)PR;QPEDDSSQAFIST(0.006)QNGS(0.994)PR;QPEDDS(0.002)S(0.007)QAFIS(0.115)T(0.054)QNGS(0.822)PR 201.96 1.0174e-20 28965100.0 25304.3 30690.6 38574.899999999994 32864.3 45560.600000000006 40186.100000000006 40612.3 31981.4 31716.3 27776.199999999997 True False 29587.81820729369 33737.35994089065 39494.671912122896 31023.01981849818 36633.3274895037 38078.670172414095 36765.2089364103 31141.92213709431 32180.090886155416 32811.805183721786 0.9017430781885922 1.0282079803895716 1.20367263218168 0.945483482081899 1.1164679079491124 1.1605173796199804 1.1204872371560293 0.9491072485260299 0.9807473470591076 1.0 15.001927347315009 -7.769842956102404 24.99932135820065 0.9736954533106182 1.0724649428742528 0.18286871468638632 0.08819652450273709 319.01050762244125 948988.8938120903 0.04835235669990832 0.02382373593607336 1.6988578601923204e-08 7.769842956102404 0.09876948956363452 QPEDDSSQAFISTQNGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 QPEDDSSQAFISTQNGSPR 19 0 Q5TCQ9-3;Q5TCQ9-2;Q5TCQ9;Q5TCQ9-1 Q5TCQ9-3 MAGI3 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 1 QPEDDSSQAFIS(0.004)T(0.014)QNGS(0.981)PR;QPEDDSSQAFIS(0.223)T(0.003)QNGS(0.773)PR 203.75 9.312199999999998e-60 13563000.0 18379.8 18911.3 20167.1 14523.5 18527.3 16747.1 16869.5 13096.0 15396.9 14490.1 True False 18117.700681557482 18867.51204675682 18509.03888525724 15591.606638975722 17437.56064007328 16030.865572396855 17742.920166902557 13704.487969298483 13662.73898545517 16994.6944781554 1.0660798112520098 1.110200131635711 1.089106892097904 0.9174396550062622 1.0260590834679097 0.9432864823196775 1.0440270161790144 0.8063980195062597 0.8039414302514792 1.0 14.052796805635444 -6.294335761185386 0.5800916077136079 0.8843657414370835 1.1120246751872838 0.4296609408527793 0.07894675807356752 0.970614817793654 0.6778928256895602 0.06035360996711301 0.11738068320177482 5.077667268202974e-07 6.294335761185386 0.2276589337502003 QPEYS(ph)PESPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QPEYSPESPR 10 0 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 QPEYS(0.5)PES(0.5)PR;QPEYS(0.989)PES(0.011)PR 105.36 0.0024718000000000006 133841000.0 36644.0 39775.0 36773.0 37156.0 38784.0 35253.0 41993.0 28961.0 31583.0 32674.0 True False 42847.105448009585 43723.599136182616 37649.80778237912 35074.269781377334 31184.553613273558 33404.27062064033 38015.11903700793 28200.804436715945 32044.841625834244 38597.53755275834 1.1100994562008673 1.132807995235902 0.9754458488683693 0.9087178096124627 0.8079415317790133 0.8654508224774854 0.9849104747950743 0.7306373987762491 0.8302302078735639 1.0 15.236221188862888 -5.5075429207381355 1.9614499750711332 0.8625071875993003 1.1294623420399295 0.6244057513785344 0.07569491850799344 0.2143647618014558 1.6029363954001246 0.02213679150881289 0.05961263358186917 3.1078287450368033e-06 5.5075429207381355 0.2669551544406291 QPEYS(ph)PESPR ddPTM_PC-9_Lapatinib_30min_R1 1 QPEYSPESPR 10 0 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 QPEY(0.006)S(0.84)PES(0.153)PR 76.24 0.023408 172030000.0 54718.0 46135.0 62351.0 53075.0 56964.0 55847.0 59708.0 44379.0 49250.0 43548.0 True False 53937.711285947764 46028.17724202592 57224.741461820224 56978.31255300976 53613.48951553296 53458.55399571553 62799.388086512234 46441.0103535047 43702.94637450828 51075.213775937475 1.0560447484873547 0.9011842308472273 1.1204014086531324 1.1155765848180033 1.049696820667862 1.0466633430108303 1.229547239136535 0.9092670773192919 0.8556586090119821 1.0 15.640335716938484 -7.870577203978357 23.44051376978288 0.911812060726687 1.0689477299056254 0.40612239613592405 0.08410098929607651 5.773395834676707 1218.8953644469073 0.04653225785956393 0.02235337815959498 1.3471712191403852e-08 7.870577203978357 0.1571356691789384 QPEYSPES(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QPEYSPESPR 10 0 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 QPEYS(0.015)PES(0.985)PR 90.79299999999999 0.008483599999999999 3027400.0 11323.0 4327.8 6881.6 10019.0 8472.6 3369.0 9628.0 6727.0 9427.8 7048.7 True False 13239.76026055597 4757.435382566214 7045.683442613335 9457.667912036257 6812.454851068006 3192.3237092144573 8715.96613931637 6550.423377845666 9565.66373935471 8326.573512521503 1.5900610546037952 0.5713557173802623 0.8461684067303356 1.1358415196615768 0.818158254511707 0.38338984270226406 1.0467650500183896 0.786688950502285 1.1488115399413532 1.0 13.023507215609028 -4.747606803768233 24.987360026196914 0.8508921982520647 1.5900629100120665 0.4737809630582538 0.2307523658345699 632.18192374662 1141916.5114760275 0.05720460416136304 1.1457385217200406 1.788105735549815e-05 4.747606803768233 0.7391707117600017 QPGQVIGATTPS(ph)TGSPTNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QPGQVIGATTPSTGSPTNK 19 0 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 QPGQVIGATT(0.006)PS(0.441)T(0.2)GS(0.352)PT(0.001)NK 188.71 4.2215999999999995e-11 18386000.0 27775.0 29425.0 30564.0 31179.0 39427.0 33056.0 34890.0 40054.0 29924.0 34408.0 True False 32476.758918744326 32346.119536949664 31292.76167461547 29432.141713681867 31701.562379087674 31322.48516823779 31584.966618274662 39002.62494072102 30361.581889353885 40645.89802642186 0.7990168872055137 0.7958028019438289 0.7698873242823572 0.724110996257224 0.7799449370876264 0.7706186033305651 0.7770763632222581 0.9595709981697874 0.7469777606984435 1.0 15.310822142783447 -9.289799336097856 0.4117291578546621 1.0247969556825993 0.7656346632074336 0.5405336522787789 0.0587951639750386 2.434798548600264 0.6460655365906702 0.1758618364813523 0.03950189978096046 5.130984041464058e-10 9.289799336097856 -0.25916229247516576 QPGQVIGATTPSTGS(ph)PTNK ddPTM_PC-9_AZD4547_30min_R2 1 QPGQVIGATTPSTGSPTNK 19 0 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 QPGQVIGATTPST(0.003)GS(0.997)PTNK 312.58 1.7466999999999994e-156 20176000.0 22574.0 20632.0 27634.0 29431.0 23152.0 22395.0 25424.0 29831.0 24105.0 25443.0 True False 29752.062431631082 27300.89051924988 27267.555104265164 22646.137654417267 19937.744432609783 20994.63710973171 27686.68674718586 25221.304398184886 25379.14108866716 24552.248314246473 1.211785660149397 1.1119507333838956 1.1105929996823602 0.9223651278109963 0.812053714080469 0.855100390034323 1.1276640083148974 1.0272502980327953 1.0336789023895983 1.0 14.583567521535253 -5.643569588285314 4.627703684666392 0.9651985923058929 1.1505195575865945 0.45647252319691567 0.08896714134476126 0.21705589200251846 7.750146898088419 0.02781071342067457 0.04949032051985547 2.2721155383296225e-06 5.643569588285314 0.18532096528070163 QPGQVIGATTPSTGS(ph)PTNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QPGQVIGATTPSTGSPTNK 19 0 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 QPGQVIGATTPST(0.003)GS(0.945)PT(0.052)NK 272.84 1.1232e-91 15098000.0 18985.0 15848.0 19184.0 21705.0 20796.0 19611.0 20454.0 21082.0 18618.0 15362.0 True False 22198.785529157896 17421.28470421677 19641.419315725143 20488.939218559433 16721.173085335107 18582.564636807576 18516.449045863854 20528.619838225404 18890.253028204468 18147.008994474912 1.2232751709064893 0.9600086002889457 1.0823502276163097 1.1290532354283591 0.9214285996345779 1.0240015113490755 1.0203581786674278 1.1312398558062986 1.0409568339309165 1.0 14.147444161135283 -4.745610709250465 24.96196961327239 1.038644465262493 1.2232756938400335 0.4402144355093808 0.0637405390945292 895.8336735420861 1412660.476711418 0.01601487780222323 0.39955808866158865 1.7963431025641713e-05 4.745610709250465 0.18463122857754044 QPGQVIGATTPSTGS(ph)PTNK ddPTM_PC-9_Lapatinib_30min_R1 2 QPGQVIGATTPSTGSPTNK 19 0 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 QPGQVIGATTPS(0.029)T(0.014)GS(0.951)PT(0.005)NK;QPGQVIGATT(0.021)PS(0.187)T(0.036)GS(0.744)PT(0.013)NK 197.41 6.891199999999999e-15 35735000.0 88239.0 95714.0 101355.0 100912.0 106025.0 108248.0 95316.0 86651.0 101456.0 85954.0 True False 86980.69567894928 95492.38011365052 93021.9831416142 108333.40511256347 99788.81795317009 103618.48537841272 100250.99609523022 90677.12179502795 90028.95690095659 100811.03437349407 0.8628092769755257 0.9472413482026332 0.922736124271652 1.0746185254998954 0.9898600740814069 1.027848647941825 0.994444672830268 0.8994761571345349 0.8930466536769076 1.0 16.62129403355896 -4.715702379060555 1.53921738376669 0.9789114848090543 0.8089738430599465 0.28962294263191524 0.05366944441805493 1.8325629988393903 3.6519918898632584 0.01649347281603586 0.49812887746443857 1.9244100706149146e-05 4.715702379060555 -0.16993764174910786 QPGQVIGATTPSTGSPT(ph)NK ddPTM_PC-9_AZD4547_30min_R2 1 QPGQVIGATTPSTGSPTNK 19 0 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 QPGQVIGATTPST(0.002)GS(0.076)PT(0.923)NK 285.46 1.3281999999999996e-105 18101000.0 20607.0 16546.0 21731.0 22193.0 24962.0 24147.0 21645.0 23173.0 22253.0 21493.0 True False 27159.597347772757 21894.17092533485 21442.832741216836 17076.746728432005 21496.457175484 22637.084272770346 23571.363068078903 19592.145312565415 23429.2481496001 20740.536611960044 1.3094934743448805 1.0556222018243038 1.0338610394897794 0.8233512491950034 1.0364465287309903 1.0914415907501958 1.1364876188635573 0.9446305888376867 1.1296355821425377 1.0 14.340165600479695 -4.752712303220387 3.6192794938194406 1.023041462405956 1.3519636458010953 0.48783105152527095 0.08704983239901173 0.28005449204957505 5.978235343056935 0.022753942460374117 0.2615129606241952 1.767208113519754e-05 4.752712303220387 0.32892218339513923 QPGQVIGATTPSTGSPT(ph)NK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QPGQVIGATTPSTGSPTNK 19 0 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 QPGQVIGATT(0.007)PS(0.002)T(0.008)GS(0.103)PT(0.881)NK 229.51 6.488099999999999e-102 0.0 16195.0 18429.0 17691.0 18326.0 18830.0 19131.0 24290.0 19894.0 20547.0 16203.0 True False 18936.493634169736 20258.509326982017 18112.82053349111 17299.253633693632 15140.396672286015 18127.73668179928 21989.075355628873 19371.803579435345 20847.461003895 19140.475637122574 0.989342897908074 1.0584120118567502 0.9463098450051917 0.9038047936563327 0.7910146518470792 0.9470891437327134 1.1488259629756272 1.0120857990521466 1.089181972231754 1.0 14.224339060511944 -7.144766949863226 8.07002955496952 1.0632305208530481 0.9359314368291354 0.400153630464271 0.07391754293221701 0.3255143964175827 20.572895343160404 0.030891210251242824 0.023916718824323616 7.165278086215881e-08 7.144766949863226 -0.12729908402391277 QPGT(ph)CSPDLAAPLDENGAVDR ddPTM_PC-9_AZD4547_30min_R2 1 QPGTCSPDLAAPLDENGAVDR 21 0 O75362 O75362 ZNF217 Zinc finger protein 217 1 QPGT(0.81)CS(0.19)PDLAAPLDENGAVDR 68.262 0.031177999999999997 0.0 987.95 914.17 889.64 933.16 736.92 1194.7 1358.7 973.28 1118.6 1161.4 True False 1302.097549363425 1209.6575749313035 877.8427923195508 718.0343791782816 634.6113781651171 1119.9952201382669 1479.6216678493322 822.8819397494348 1177.7269123328394 1120.7397395026478 1.1618197369723489 1.0793385228475212 0.7832708713524447 0.6406789675334656 0.5662433085907522 0.9993356893325551 1.320218794513297 0.7342310714480476 1.0508478202579672 1.0 10.130235576077093 -6.96900756971812 24.999365792385856 1.0264059159833627 0.8381460353487178 0.14481136094021152 0.21257020650223837 420.72860825970093 339370.40617468185 0.0814464593074499 0.07182830896907422 1.0739706929547367e-07 6.96900756971812 -0.18825988063464494 QPGVDS(ph)LSPVASLPK ddPTM_PC-9_AZD4547_30min_R2 1 QPGVDSLSPVASLPK 15 0 Q9UBW7;A0A087X151;Q9UBW7-2 Q9UBW7 ZMYM2 Zinc finger MYM-type protein 2 1 QPGVDS(0.566)LS(0.434)PVASLPK 150.76 0.00014109 8095500.0 22038.0 22268.0 27229.0 27856.0 39774.0 33086.0 27083.0 36519.0 31711.0 30156.0 True False 29045.62558112368 29465.695525526196 26867.92566888745 21434.22957090983 34252.0666492148 31017.12718966662 29493.334533276986 30875.827673135795 33387.178720710406 29100.24761877202 0.9981229700047946 1.0125582404501063 0.9232885582580217 0.7365651953106753 1.1770369482051912 1.0658715896856512 1.0135080264489362 1.06101597751417 1.147315966451535 1.0 14.828743808863576 -6.284400979926823 24.9982017960758 1.0767320475484168 0.9248179285336936 0.4528875941014757 0.08591079722277513 803.4897009551544 874753.541168356 0.027715825264049213 0.031446970296945286 5.195161107918303e-07 6.284400979926823 -0.15191411901472318 QPGVDSLS(ph)PVASLPK ddPTM_PC-9_AZD4547_30min_R2 1 QPGVDSLSPVASLPK 15 0 Q9UBW7;A0A087X151;Q9UBW7-2 Q9UBW7 ZMYM2 Zinc finger MYM-type protein 2 1 QPGVDS(0.006)LS(0.994)PVASLPK 132.81 5.6387e-06 10709000.0 14654.0 11654.0 17723.0 19860.0 15737.0 20404.0 17536.0 19124.0 17427.0 16510.0 True False 19313.667177864896 15420.927593608869 17487.981439997504 15281.583833941326 13552.189190393055 19128.13465447492 19096.670028266646 16168.825225801625 18348.155642074373 15931.989925252888 1.2122570544218023 0.9679222536518202 1.0976646057425823 0.9591760919782757 0.8506275270054152 1.2006117719266196 1.198636838076178 1.0148653935672745 1.1516549864867638 1.0 13.959638852062385 -6.800951334366629 24.999998181395867 1.1194254865275588 1.0159827378231192 0.16199594108005677 0.1082471795145988 284.607025680933 180074.55747773548 0.03824480232242603 0.033729195921247804 1.5814252387335032e-07 6.800951334366629 -0.10344274870443959 QPGVDSLS(ph)PVASLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QPGVDSLSPVASLPK 15 0 Q9UBW7;A0A087X151;Q9UBW7-2 Q9UBW7 ZMYM2 Zinc finger MYM-type protein 2 1 QPGVDS(0.001)LS(0.997)PVAS(0.002)LPK;QPGVDS(0.245)LS(0.754)PVAS(0.001)LPK 212.41 5.2252999999999995e-14 12966700.0 60776.0 64134.0 65708.0 67063.0 77086.0 57492.0 69856.0 52606.0 58442.0 59495.0 True False 71064.17641928373 70500.7996731599 67274.72791897785 63305.6775311795 61981.551666481086 54477.01831111829 63238.733966356966 51225.14824066436 59296.60368859842 70280.97253783901 1.0111438964653348 1.0031278328597761 0.9572253412224395 0.9007513021692458 0.8819108419865768 0.7751318222266783 0.8997987888159839 0.7288622566098517 0.8437077852995468 1.0 16.100846534837252 -5.820937727008773 1.268665729048893 0.8363542498499628 1.0137658167851198 0.4393171524894741 0.06888829698190092 0.38775320395260865 1.2493314417751322 0.023114185538367953 0.05434176078554324 1.5102966983625609e-06 5.820937727008773 0.17741156693515703 QPGVDSLS(ph)PVASLPK ddPTM_PC-9_Lapatinib_30min_R1 2 QPGVDSLSPVASLPK 15 0 Q9UBW7;A0A087X151;Q9UBW7-2 Q9UBW7 ZMYM2 Zinc finger MYM-type protein 2 1 QPGVDS(0.019)LS(0.981)PVASLPK;QPGVDSLS(0.999)PVASLPK 205.65 7.5003e-13 16941900.0 40823.0 48009.0 48540.0 50481.0 62955.0 65140.0 64784.0 60043.0 57256.0 56584.0 True False 40240.85653397868 47897.838110164186 44549.22856981853 54193.54113967941 59252.11067429216 62354.11404875658 68138.19852945347 62832.816977748116 50807.22634759083 66364.46900655943 0.6063614632402362 0.7217391900691617 0.6712813232245601 0.8166047578007886 0.8928288218268681 0.9395707519726185 1.026727095830733 0.9467839932771518 0.7655787367569997 1.0 16.01812342070324 -5.984703495389785 1.5902925648893607 0.9373800717196413 0.6585740985699425 0.738900473910923 0.07000296553267324 0.20004508031022555 1.023131840768355 0.024234620789512187 0.04199616559417767 1.0358491275874384e-06 5.984703495389785 -0.2788059731496988 QPGYQPPNPHPGPS(ph)SPPAAPASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QPGYQPPNPHPGPSSPPAAPASK 23 0 Q9BUL9 Q9BUL9 RPP25 Ribonuclease P protein subunit p25 1 QPGYQPPNPHPGPS(0.568)S(0.425)PPAAPAS(0.007)K;QPGYQPPNPHPGPS(0.857)S(0.143)PPAAPASK 134.26 9.109100000000001e-07 82582000.0 102999.0 110400.0 133049.0 126503.0 153118.0 135998.0 131620.0 109751.0 104026.0 87246.0 True False 120434.6963770205 121359.78239181783 136221.39275114267 119415.44703825987 123115.62706676003 128866.02546920371 119152.00075372063 106870.15254079679 105547.183452143 103063.00916104381 1.1685540462808737 1.177529972972009 1.3217292398117968 1.158664471475543 1.1945665866827397 1.2503615653977338 1.156108304265952 1.0369399594553272 1.024103451969052 1.0 16.653167095447508 -7.695007107006677 2.8066151579560334 1.0156378261134924 1.2121437750171367 0.7841175732527333 0.04501977414652645 0.12243175013231572 1.9378970662834094 0.026756605466576634 0.012906043528069445 2.0183333344204242e-08 7.695007107006677 0.19650594890364426 QPGYQPPNPHPGPS(ph)SPPAAPASK ddPTM_PC-9_Lapatinib_30min_R1 3 QPGYQPPNPHPGPSSPPAAPASK 23 0 Q9BUL9 Q9BUL9 RPP25 Ribonuclease P protein subunit p25 1 QPGYQPPNPHPGPS(0.733)S(0.266)PPAAPASK;QPGYQPPNPHPGPS(0.82)S(0.177)PPAAPAS(0.003)K;QPGYQPPNPHPGPS(0.817)S(0.183)PPAAPASK 113.05 1.2679e-07 86408000.0 126165.0 146709.0 197586.0 160001.0 212524.0 209127.0 168555.0 191717.0 223330.0 176567.0 True False 124365.86396417262 146369.30432427424 181341.24178401646 171768.00728768957 200023.75615826 200183.1257088474 177281.95315405112 200624.87171731837 198176.22363084138 207086.37068926104 0.6005506955877223 0.7068031751056448 0.8756792693813932 0.8294510484489215 0.9658953193901945 0.9666648994936893 0.8560773582732188 0.9687980481263138 0.9569737639963299 1.0 17.659873080694155 -4.169009275855248 0.6029029774906226 0.9548485724650925 7.92542095144134e-18 0.874674228149669 0.04390336681094551 2.279067138932162 0.3661538855712377 0.020888819282562903 1.7796601978575517 6.77627034395678e-05 4.169009275855248 -0.9548485724650925 QPGYQPPNPHPGPS(ph)SPPAAPASKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QPGYQPPNPHPGPSSPPAAPASKR 24 1 Q9BUL9 Q9BUL9 RPP25 Ribonuclease P protein subunit p25 1 QPGYQPPNPHPGPS(0.5)S(0.5)PPAAPAS(0.001)KR;QPGY(0.001)QPPNPHPGPS(0.493)S(0.493)PPAAPAS(0.014)KR 50.924 0.0091089 9172100.0 39757.0 17334.1 29327.9 48516.0 61255.0 83503.0 51053.0 69915.0 76043.0 46186.0 True False 46487.074863457 19054.91489092403 30027.18836268012 45797.80581099421 49252.522472696764 79123.9556813698 46216.89024828818 68079.80533106586 77154.9850157779 54559.15619182517 0.8520490071366308 0.3492523752370479 0.5503602045659794 0.8394155813182516 0.9027361475226863 1.45024155804714 0.8470968664873351 1.2478163168745366 1.41415282788663 1.0 15.735533711461333 -6.218041601423637 1.7553010079919964 1.183286834305256 0.5656390717208464 0.5963138849304608 0.2118637997834524 0.23701406876085232 1.4419377471331878 0.07272926005737684 0.10002497368468871 6.052828914335839e-07 6.218041601423637 -0.6176477625844097 QPGYQPPNPHPGPSS(ph)PPAAPASK ddPTM_PC-9_AZD4547_30min_R2 3 QPGYQPPNPHPGPSSPPAAPASK 23 0 Q9BUL9 Q9BUL9 RPP25 Ribonuclease P protein subunit p25 1 QPGYQPPNPHPGPS(0.248)S(0.689)PPAAPAS(0.063)K;QPGYQPPNPHPGPS(0.257)S(0.743)PPAAPASK;QPGYQPPNPHPGPS(0.254)S(0.732)PPAAPAS(0.014)K 97.999 4.2655e-06 128559000.0 124844.0 123169.0 186802.0 173181.0 176430.0 183588.0 161802.0 202060.0 170086.0 168105.0 True False 164541.79508348348 162980.9705489284 184324.88342574146 133256.79606977798 151935.73990347917 172108.21333786193 176202.0645479928 170836.2698768815 179076.39872254906 162219.6951171794 1.0143145378532903 1.004692866863047 1.136266982209493 0.8214587998918377 0.9366047679582211 1.0609575687683273 1.0861940310066127 1.0531166992607028 1.1039128053667788 1.0 17.30758946244414 -6.838142935009946 8.906441171987854 1.0661260477967538 0.983549885404629 0.20263020075680127 0.07719010098628032 0.5057038378435945 53.459497378911784 0.028427355067667495 0.025090943249618906 1.4516337772162477e-07 6.838142935009946 -0.08257616239212484 QPGYQPPNPHPGPSS(ph)PPAAPASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QPGYQPPNPHPGPSSPPAAPASK 23 0 Q9BUL9 Q9BUL9 RPP25 Ribonuclease P protein subunit p25 1 QPGYQPPNPHPGPS(0.25)S(0.749)PPAAPAS(0.002)K 111.27 4.1648999999999994e-07 42061000.0 29895.0 30689.0 36048.0 39155.0 46155.0 37013.0 39918.0 32063.0 32362.0 28786.0 True False 34955.633046835705 33735.60110346469 36907.5210328013 36961.27229222276 37111.25907643976 35071.9731223374 36136.67805870698 31221.380223556636 32835.23302711102 34004.67393014939 1.0279655414029178 0.9920871810964159 1.0853661208048866 1.0869468229028358 1.0913575925671795 1.0313868380088103 1.062697384863535 0.9181496722388797 0.9656094069468046 1.0 15.05344543745394 -7.7503936360675265 24.98446473744764 0.9564096543144258 1.0546372055849635 0.5994418099654055 0.03466205604104957 138.59929966140527 313500.70666809194 0.017471886804897252 0.009963846004616406 1.7766683424154e-08 7.7503936360675265 0.09822755127053773 QPGYQPPNPHPGPSS(ph)PPAAPASK ddPTM_PC-9_Lapatinib_30min_R1 1 QPGYQPPNPHPGPSSPPAAPASK 23 0 Q9BUL9 Q9BUL9 RPP25 Ribonuclease P protein subunit p25 1 QPGYQPPNPHPGPS(0.262)S(0.737)PPAAPAS(0.001)K 90.744 1.0891e-05 34128000.0 20413.0 20214.0 25762.0 25047.0 28414.0 31014.0 27341.0 25764.0 29163.0 20232.0 True False 20121.906876714256 20167.19572494446 23643.9478041958 26889.039934342607 26742.744384073336 29687.603517165117 28756.58319945956 26961.089496106157 25878.355839995664 23729.07424255458 0.847985331034474 0.8498939115280605 0.996412568080464 1.133168519744487 1.127003274999839 1.251106689359368 1.2118712641510847 1.1362048607760449 1.090575872259975 1.0 14.534368196401232 -5.521133913559208 1.9917095760589405 1.1523229189689548 0.838822593836726 0.7593564451679404 0.0644690626672039 0.15394090749996261 1.1933411615692282 0.01911794962426362 0.050030056469241205 3.0120771149380074e-06 5.521133913559208 -0.3135003251322288 QPGYQPPNPHPGPSS(ph)PPAAPASKR ddPTM_PC-9_Lapatinib_30min_R1 1 QPGYQPPNPHPGPSSPPAAPASKR 24 1 Q9BUL9 Q9BUL9 RPP25 Ribonuclease P protein subunit p25 1 QPGYQPPNPHPGPS(0.48)S(0.517)PPAAPAS(0.003)KR 71.097 0.0048591 0.0 7390.9 2403.7 2999.6 3040.0 2433.9 2025.4 2237.2 1152.9 3963.3 955.61 True False 7285.504410674936 2398.1343803328864 2752.9844667908455 3263.5717411427127 2290.74278723151 1938.7783634380048 2353.0312692963294 1206.4679428683744 3516.9114186007882 1120.785915229714 6.5003532893092375 2.1396899691065174 2.456298236248445 2.9118600589068055 2.0438718546547796 1.7298382653574271 2.0994475727454667 1.0764481659471061 3.137897586694752 1.0 10.13029501549713 -4.761354015286654 8.186115407310185 2.093910540701739 6.549565027878649 0.8060336668809026 0.652475060031125 0.037022532668686776 23.718778940276405 0.1563918326390777 0.9118642667161488 1.7323912627414602e-05 4.761354015286654 4.4556544871769095 QPLFVPT(ph)TSGPSTPPGLVLPHTEFQPAPK ddPTM_PC-9_AZD4547_30min_R2 1 QPLFVPTTSGPSTPPGLVLPHTEFQPAPK 29 0 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 QPLFVPT(0.293)T(0.293)S(0.048)GPS(0.2)T(0.166)PPGLVLPHTEFQPAPK 64.733 0.00048146 5636100.0 24347.0 20522.0 25375.0 29610.0 30903.0 25553.0 26576.0 31030.0 24171.0 25326.0 True False 32088.8395509401 27155.33517041711 25038.51092026954 22783.87196993971 26612.651874608684 23955.166870505665 28941.21251546615 26235.02649846392 25448.629713925482 24439.344448634463 1.3129991935087706 1.1111318974815791 1.0245164706808882 0.9322619932717855 1.0889265843665317 0.9801886020655578 1.1842057619955197 1.0734750497749046 1.0412975588364202 1.0 14.576917966940611 -4.786979928802428 2.834608070140191 1.0446269793465235 1.3596259833448732 0.6173377641862052 0.06450753176091398 0.28727013930529066 3.2321866380987356 0.017073455963555348 0.21174040027472066 1.6331274221798264e-05 4.786979928802428 0.3149990039983497 QPLFVPTTSGPS(ph)TPPGLVLPHTEFQPAPK ddPTM_PC-9_Lapatinib_30min_R1 2 QPLFVPTTSGPSTPPGLVLPHTEFQPAPK 29 0 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 QPLFVPT(0.164)T(0.12)S(0.032)GPS(0.342)T(0.342)PPGLVLPHTEFQPAPK;QPLFVPT(0.201)T(0.174)S(0.045)GPS(0.287)T(0.287)PPGLVLPHT(0.007)EFQPAPK 68.587 7.7535e-05 5965500.0 30767.0 33698.0 29675.0 26481.0 29072.0 33997.0 27832.0 28540.0 30403.0 25411.0 True False 30328.2569380232 33619.97435139893 27235.236048812607 28428.501078026376 27362.04211775113 32543.027560877767 29273.004776978116 29866.072590392414 26978.69398221678 29803.257491970853 1.0176155054927734 1.1280637480804345 0.9138342027259911 0.9538722767363654 0.9180889748418475 1.0919285440406983 0.9822082295824344 1.0021076588167748 0.9052263494849506 1.0 14.863182405225869 -5.259989094096246 24.999507394645768 0.9732144428841112 1.0728396248991297 0.3318386336613762 0.05778144528323066 144.8329006243238 2496526.5665360037 0.014940056438852153 0.03547324099316423 5.495546739757006e-06 5.259989094096246 0.09962518201501847 QPLLLS(ph)EDEEDTK ddPTM_PC-9_AZD4547_30min_R2 2 QPLLLSEDEEDTK 13 0 Q99613-2;Q99613;B5ME19;H3BPE4 Q99613-2 EIF3C;EIF3CL Eukaryotic translation initiation factor 3 subunit C;Eukaryotic translation initiation factor 3 subunit C-like protein 1 QPLLLS(0.991)EDEEDT(0.009)K;QPLLLS(1)EDEEDTK 167.29 0.00028539999999999994 8882100.0 18917.0 22801.3 23540.0 24746.0 24392.0 21545.0 27093.0 21585.0 23008.0 23710.8 True False 24932.212501956456 30171.37432127628 23227.844219237235 19041.192021888823 21005.591836567797 20197.787744102254 29504.224513904417 18249.534223955645 24224.15590823704 22880.692109005846 1.0896616406172055 1.318639059410306 1.0151722731365609 0.832194757535075 0.9180487957486212 0.8827437407871241 1.289481295991547 0.7975953759183982 1.058716047260756 1.0 14.48184307183746 -5.418269335052879 6.155596031501876 0.9645439675453386 1.201203626640836 0.30491501754608086 0.14014092663367073 0.2611326655202753 12.96200516040459 0.03600840806253152 0.07584962366870773 3.817074750881441e-06 5.418269335052879 0.23665965909549735 QPLLLS(ph)EDEEDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QPLLLSEDEEDTK 13 0 Q99613-2;Q99613;B5ME19;H3BPE4 Q99613-2 EIF3C;EIF3CL Eukaryotic translation initiation factor 3 subunit C;Eukaryotic translation initiation factor 3 subunit C-like protein 1 QPLLLS(0.999)EDEEDT(0.001)K;QPLLLS(1)EDEEDTK;QPLLLS(0.75)EDEEDT(0.25)K 169.37 7.4562e-05 12805100.0 33118.3 41259.2 28224.3 41174.9 42122.899999999994 34997.4 48872.7 35782.7 35543.4 30957.5 True False 38724.574073758755 45355.14070344652 28897.27435325381 38868.003843826904 33869.22012676772 33162.07473459842 44243.12404829324 34843.44203990456 36063.154983493514 36569.84969056484 1.0589207886120964 1.2402331726058016 0.7901939602641959 1.0628428657133637 0.9261514721376093 0.9068146305002276 1.2098251544005698 0.952791502692293 0.9861444684252542 1.0 15.158367076474223 -5.235866909442084 24.99892862491719 0.9843827473521035 1.1495769659087998 0.27487391228144786 0.11035369946100462 1008.1976299306683 985582.3706193845 0.02719592030996881 0.0718992597501238 5.80942421406418e-06 5.235866909442084 0.16519421855669625 QPLLLS(ph)EDEEDTK ddPTM_PC-9_Lapatinib_30min_R1 3 QPLLLSEDEEDTK 13 0 Q99613-2;Q99613;B5ME19;H3BPE4 Q99613-2 EIF3C;EIF3CL Eukaryotic translation initiation factor 3 subunit C;Eukaryotic translation initiation factor 3 subunit C-like protein 1 QPLLLS(0.861)EDEEDT(0.139)K;QPLLLS(0.821)EDEEDT(0.179)K;QPLLLS(1)EDEEDTK 155.57 0.00018934 9647200.0 24792.1 25309.5 17686.9 25087.2 23281.9 21637.2 21928.9 23437.4 30059.5 19321.6 True False 24438.560107685684 25250.897407761047 16232.751355408385 26932.196376445878 21912.504415976542 20711.82739477671 23064.271143068232 24526.38716643529 26673.88256943212 22661.312815586334 1.0784264930528193 1.1142733703580319 0.7163199893804733 1.1884658490712883 0.9669565304665506 0.913972970733241 1.0177817733138896 1.082302131656122 1.177066959293107 1.0 14.467943821364257 -7.744162002722768 3.9741144074162738 1.0999541493565477 0.9945191523662983 0.09001721580933231 0.1264115872196753 0.48177848446023647 16.716910945211882 0.0677972773909856 0.03400411740485 1.802345295495856e-08 7.744162002722768 -0.10543499699024939 QPLLLS(ph)EDEEDTKR ddPTM_PC-9_AZD4547_30min_R2 12 QPLLLSEDEEDTKR 14 1 Q99613-2;Q99613;B5ME19;H3BPE4 Q99613-2 EIF3C;EIF3CL Eukaryotic translation initiation factor 3 subunit C;Eukaryotic translation initiation factor 3 subunit C-like protein 1 QPLLLS(1)EDEEDTKR;QPLLLS(1)EDEEDTKR;QPLLLS(1)EDEEDTKR;QPLLLS(1)EDEEDTKR;QPLLLS(1)EDEEDTKR;QPLLLS(0.999)EDEEDT(0.001)KR;QPLLLS(1)EDEEDTKR;QPLLLS(0.998)EDEEDT(0.002)KR;QPLLLS(1)EDEEDTKR;QPLLLS(1)EDEEDTKR;QPLLLS(0.989)EDEEDT(0.011)KR;QPLLLS(0.999)EDEEDT(0.001)KR 200.81 5.5045e-08 3253096100.0 3471624.6 3269235.8 3288049.5 4645085.6 3887190.7 3586519.1 3584052.6 3644943.1 3368473.3 3569674.0 True False 4575529.008522468 4325952.338959499 3244447.8152566245 3574232.880777117 3347521.36910062 3362253.493709376 3903026.338170111 3081700.8963549286 3546523.921763464 3444700.799784211 1.3282805313045174 1.2558281808482448 0.9418663633892003 1.0376032893774172 0.9717887165440672 0.9760654666785574 1.1330523505596224 0.8946207741897287 1.0295593515656372 1.0 21.715947247924753 -5.170952117899421 4.618443827169112 0.998981510985354 1.309233520363944 0.7896967908913671 0.060963254110260164 0.08863677984253812 3.216051517042028 0.015036872852831876 0.04324289522286464 6.746024002739886e-06 5.170952117899421 0.31025200937859 QPLLLS(ph)EDEEDTKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 13 QPLLLSEDEEDTKR 14 1 Q99613-2;Q99613;B5ME19;H3BPE4 Q99613-2 EIF3C;EIF3CL Eukaryotic translation initiation factor 3 subunit C;Eukaryotic translation initiation factor 3 subunit C-like protein 1 QPLLLS(0.998)EDEEDT(0.002)KR;QPLLLS(1)EDEEDTKR;QPLLLS(0.972)EDEEDT(0.028)KR;QPLLLS(1)EDEEDTKR;QPLLLS(0.991)EDEEDT(0.009)KR;QPLLLS(1)EDEEDTKR;QPLLLS(1)EDEEDTKR;QPLLLS(0.878)EDEEDT(0.122)KR;QPLLLS(0.997)EDEEDT(0.003)KR;QPLLLS(0.997)EDEEDT(0.003)KR;QPLLLS(0.998)EDEEDT(0.002)KR;QPLLLS(1)EDEEDTKR;QPLLLS(1)EDEEDTKR 138.28 0.00010857 2771965400.0 1840548.0 2032839.0 2071636.0 2410457.0 2482465.0 2355218.6 2471478.0 1933408.0 2188371.3 1854854.9 True False 2152116.4239199637 2234645.821355084 2121031.6589632756 2275406.909097034 1996043.8037741096 2231706.790490614 2237361.7118887943 1882658.0886151036 2220372.090270749 2191125.4103466864 0.9821968262325292 1.0198621269247714 0.968010159960529 1.0384649360334937 0.9109673934447639 1.0185207929917195 1.0211016226290728 0.8592196867075828 1.0133477891251488 1.0 21.06324062951144 -6.34398376748316 0.8839679218244441 0.967136302047041 0.9999051861049417 0.022374928600632615 0.053331947331364676 2.1801483318257855 3.6888580140475544 0.027536360277549177 0.04086819974547414 4.5291450806018555e-07 6.34398376748316 0.03276888405790068 QPLLLS(ph)EDEEDTKR ddPTM_PC-9_Lapatinib_30min_R1 12 QPLLLSEDEEDTKR 14 1 Q99613-2;Q99613;B5ME19;H3BPE4 Q99613-2 EIF3C;EIF3CL Eukaryotic translation initiation factor 3 subunit C;Eukaryotic translation initiation factor 3 subunit C-like protein 1 QPLLLS(0.996)EDEEDT(0.004)KR;QPLLLS(1)EDEEDTKR;QPLLLS(1)EDEEDTKR;QPLLLS(0.999)EDEEDT(0.001)KR;QPLLLS(1)EDEEDTKR;QPLLLS(0.994)EDEEDT(0.006)KR;QPLLLS(0.516)EDEEDT(0.484)KR;QPLLLS(1)EDEEDTKR;QPLLLS(0.563)EDEEDT(0.437)KR;QPLLLS(1)EDEEDTKR;QPLLLS(0.701)EDEEDT(0.299)KR;QPLLLS(0.996)EDEEDT(0.004)KR 174.21 2.3259000000000002e-05 5682668900.0 1165707.2 1122769.0 1022112.0 1033106.4 972293.0 983683.8999999999 889346.6000000001 890570.5 1105945.2000000002 852059.8 True False 1149084.0015634834 1120169.2973632235 938077.8968264194 1109084.4909979205 915104.637341587 941614.0326761696 935392.6153416669 931949.6566174512 981382.0054567477 999337.2011316832 1.1498461182694109 1.1209122367252073 0.9387000661679644 1.109820078489979 0.9157115699338437 0.9422385473190171 0.9360130037012498 0.9325677614743851 0.9820328957486998 1.0 19.930612035654 -4.719012706069071 0.7137215675270713 0.9509412962553234 1.3098050818459614 0.5803871566563252 0.0550492489047496 2.1652271408838533 0.78664894419725 0.02255440528274054 0.6421382427482683 1.9097973831787996e-05 4.719012706069071 0.35886378559063803 QPLSEASNQQPLS(ph)GGEEK ddPTM_PC-9_AZD4547_30min_R2 4 QPLSEASNQQPLSGGEEK 18 0 Q9NQW6;Q9NQW6-2;C9JJT6 Q9NQW6 ANLN Actin-binding protein anillin 1 QPLSEASNQQPLS(1)GGEEK;QPLSEAS(0.313)NQQPLS(0.687)GGEEK;QPLSEASNQQPLS(1)GGEEK;QPLSEAS(0.011)NQQPLS(0.989)GGEEK 298.42 3.349599999999999e-121 55249100.0 114638.0 112607.0 145843.0 143887.0 130748.0 118505.0 143777.0 147599.0 149951.0 136473.0 True False 151090.49938147128 149005.01060009556 143909.02652787647 110716.07518198973 112595.89707476109 111094.86361637681 156572.8744670444 124790.96603760181 157877.10372896615 131695.12180914817 1.1472748368039842 1.1314391038419234 1.0927437899820514 0.8406998957974984 0.854973939262036 0.8435761483813717 1.1889041318777847 0.9475747037802067 1.1988075303029124 1.0 17.0068423813669 -5.541947091200247 24.389596643852443 0.9766184805565311 1.1325406324015739 0.22767426443952465 0.1212490150106225 255.7277113332305 327089.9729036825 0.03447318253561988 0.05972220758135973 2.8711303419543704e-06 5.541947091200247 0.15592215184504277 QPLSEASNQQPLS(ph)GGEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QPLSEASNQQPLSGGEEK 18 0 Q9NQW6;Q9NQW6-2;C9JJT6 Q9NQW6 ANLN Actin-binding protein anillin 1 QPLSEASNQQPLS(1)GGEEK;QPLSEASNQQPLS(1)GGEEK;QPLSEASNQQPLS(1)GGEEK;QPLSEASNQQPLS(1)GGEEK 267.69 2.8438999999999993e-78 42484300.0 129605.0 147486.0 126276.0 143231.0 142315.0 133014.0 150746.0 144471.0 127350.0 105373.0 True False 151544.56668456757 162127.4353789826 129286.89874439701 135206.23143116725 114429.39736677585 126038.51168223572 136466.24757347142 140678.7893296775 129212.25282747032 124476.2907677911 1.2174572824255503 1.302476434499717 1.0386467812218154 1.086200678034283 0.9192866903484649 1.012550349185444 1.0963232173108968 1.1301653388122879 1.0380471014236285 1.0 16.92551145007083 -5.267656178692344 24.746805874483364 1.0431495189322846 1.25996686456748 0.6940155387052799 0.05835514599086799 226.06488311256783 899885.0511488335 0.01627974798229869 0.035278646689371425 5.399379102221486e-06 5.267656178692344 0.2168173456351954 QPLSEASNQQPLS(ph)GGEEK ddPTM_PC-9_Lapatinib_30min_R1 4 QPLSEASNQQPLSGGEEK 18 0 Q9NQW6;Q9NQW6-2;C9JJT6 Q9NQW6 ANLN Actin-binding protein anillin 1 QPLSEASNQQPLS(1)GGEEK;QPLSEASNQQPLS(1)GGEEK;QPLSEASNQQPLS(1)GGEEK;QPLSEAS(0.002)NQQPLS(0.998)GGEEK 179.78 1.0053e-08 59170000.0 190471.0 204639.0 198212.0 192505.0 214028.0 187749.0 172955.0 197825.0 196923.0 170720.0 True False 187754.84861189668 204165.17096848294 181915.77448044642 206662.45987785433 201439.29383523797 179719.41293429522 181909.76362468573 207016.67169566816 174743.45804887914 200228.72452989896 0.9377018659670899 1.0196597488588415 0.9085398456567705 1.032131929936929 1.0060459322616233 0.8975705826236674 0.9085098257094587 1.0339009659163843 0.8727192287677273 1.0 17.61128943044978 -6.7410419527230285 24.990489263179118 0.9425320110719594 0.9818094100956686 0.10382850232758778 0.05618722717141274 574.5931816175447 703977.3966905101 0.017917692068459074 0.017898156086202068 1.815340292948632e-07 6.7410419527230285 0.03927739902370919 QPPAS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 1 QPPASPPR 8 0 H3BQL8;H3BND2;Q9BWN1 H3BQL8 PRR14 Proline-rich protein 14 1 QPPAS(1)PPR 70.399 0.038245 8727300.0 18644.0 14304.0 25357.0 20038.0 19418.0 16014.0 18936.0 17731.0 19051.0 20911.0 True False 18378.13314110914 14270.879966835144 23272.245340850586 21511.661364808453 18275.87141725685 15329.118550457291 19916.4134254404 18554.846990197882 16905.275764076297 24525.43848784393 0.7493498291668991 0.5818807265732895 0.9489023143209248 0.8771162797138465 0.7451802105929854 0.6250293367050376 0.812071655122986 0.7565551580003195 0.689295556222386 1.0 14.581991310023842 -11.641909002949973 2.3870684651299148 1.4695110469701176 0.7559670255818641 0.3370675091822184 0.10349163835586522 14324576.390558679 3882649.5781055293 36470920.57796525 0.026714285894215803 2.280819918601765e-12 11.641909002949973 -0.7135440213882535 QPPAT(ph)TPPFK ddPTM_PC-9_AZD4547_30min_R2 1 QPPATTPPFK 10 0 A0A0A0MTR7;A0A0A0MTC1;Q63HN8;Q63HN8-4;Q63HN8-5 A0A0A0MTR7 RNF213 E3 ubiquitin-protein ligase RNF213 1 QPPAT(0.5)T(0.5)PPFK 79.283 0.032104 0.0 35575.0 32207.0 43636.0 47988.0 45920.0 43100.0 40762.0 51566.0 35051.0 40472.0 True False 46887.10999403192 42617.28290778792 43057.3581287441 36925.108007209245 39544.80063689705 40404.95018662366 44389.73903354271 43597.65956879765 36903.72430196526 39055.08759871803 1.200537826871267 1.0912095075978478 1.1024775714536468 0.9454621734972448 1.0125390331526256 1.0345630408456679 1.1365929962732892 1.1163119134888004 0.9449146467457061 1.0 15.253222876069035 -4.7507407107686035 1.4951213452953094 1.03873530709475 1.268141334208574 0.40146729992869123 0.062088026258076995 1.3933149536375469 2.7511870008709525 0.01868648566006171 0.48855864017977096 1.775249051296781e-05 4.7507407107686035 0.22940602711382385 QPPAT(ph)TPPFK ddPTM_PC-9_Lapatinib_30min_R1 1 QPPATTPPFK 10 0 A0A0A0MTR7;A0A0A0MTC1;Q63HN8;Q63HN8-4;Q63HN8-5 A0A0A0MTR7 RNF213 E3 ubiquitin-protein ligase RNF213 1 QPPAT(0.5)T(0.5)PPFK 99.5 0.010634999999999999 2310500.0 23091.0 30193.0 35819.0 27507.0 27487.0 28911.0 27522.0 26433.0 35075.0 25091.0 True False 22761.718105629214 30123.089963552375 32874.100085338476 29529.956540662064 25870.268701521214 27674.543924832673 28946.954493819758 27661.173678410727 31124.484143875718 29427.94591834405 0.7734728808047927 1.0236219016827472 1.117104815149407 1.0034664540502103 0.8791054861017282 0.9404171124149584 0.9836552837952424 0.9399627739959928 1.0576505825530325 1.0 14.844899224687428 -8.259028823556145 24.965198928211528 1.0288252921988386 0.964326372343837 0.09339516003838177 0.08676258086787332 559.0643895368453 5790207.25989147 0.06819124780428283 0.022790207686797424 5.50771141232835e-09 8.259028823556145 -0.06449891985500156 QPPGPVPT(ph)PPLPSER ddPTM_PC-9_AZD4547_30min_R2 2 QPPGPVPTPPLPSER 15 0 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QQI0 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 QPPGPVPT(0.599)PPLPS(0.401)ER;QPPGPVPT(0.851)PPLPS(0.149)ER 117.13 0.0003262 27672000.0 1848.2 13793.900000000001 15664.2 27259.2 16975.9 11239.4 24026.0 13822.7 11466.3 9169.0 True False 2435.8891550518547 18252.508420583603 15456.482473193533 20975.01259044176 14619.089310363699 10536.598541242189 26164.26745547072 11686.71932904664 12072.385209084603 8847.996100826398 0.2753040493343282 2.0628974303999557 1.7468907419330695 2.370594691885398 1.6522486158191552 1.1908457487066564 2.957083972158056 1.3208323326402807 1.3644202677662853 1.0 13.11113503446169 QPPGPVPT(ph)PPLPSER ddPTM_PC-9_Lapatinib_30min_R1 1 QPPGPVPTPPLPSER 15 0 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QQI0 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 QPPGPVPT(0.964)PPLPS(0.036)ER 93.738 0.0077816000000000005 11932000.0 5672.4 4711.5 10461.0 3189.1 5089.3 10224.0 7178.3 6280.3 3520.0 4020.6 True False 5591.510535809242 4700.590811223698 9600.936960627754 3423.6370525257325 4789.957379948775 9786.743353308068 7549.957250308352 6572.105665362351 3123.5405327567364 4715.555352887255 1.185758647151847 0.9968265579462673 2.036014051823029 0.7260305088836455 1.0157779988768374 2.075416917185758 1.601074886266713 1.3937076703676825 0.6623908106272669 1.0 12.203211972354701 QPPGPVPTPPLPS(ph)ER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QPPGPVPTPPLPSER 15 0 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QQI0 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 QPPGPVPT(0.319)PPLPS(0.681)ER;QPPGPVPT(0.362)PPLPS(0.638)ER 127.05 2.1878000000000003e-05 14220800.0 7091.9 6485.6 15600.8 16972.4 19259.7 14593.4 16673.7 12581.6 16163.5 10082.400000000001 True False 8292.418598590204 7129.447506162817 15972.782238363467 16021.49145326323 15485.90004191328 13828.096413787553 15094.246428865741 12251.346331307119 16399.860609162257 11910.259307765522 0.6962416505225477 0.5985971692080959 1.3410944149594768 1.3451841004685072 1.300215187742926 1.161023958963815 1.2673314693513222 1.0286380854293582 1.376952439521573 1.0 13.53991720315911 -5.258001076218717 24.979229742971466 1.2344182832283632 0.6474193494392972 0.7743287295077095 0.12523129837235447 119.35906247866255 867132.2734283502 0.031208237447652044 0.07588881729439131 5.520760711875352e-06 5.258001076218717 -0.586998933789066 QPPGTQQSHS(ph)SPGEITSSPQGLDNPALLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QPPGTQQSHSSPGEITSSPQGLDNPALLR 29 0 Q5TDH0-2;Q5TDH0;Q5TDH0-3 Q5TDH0-2 DDI2 Protein DDI1 homolog 2 1 QPPGTQQS(0.001)HS(0.847)S(0.152)PGEITSSPQGLDNPALLR 144.18 4.962100000000001e-11 12455000.0 1971.9 4475.1 6283.0 6323.6 6838.4 4879.7 6480.5 4926.5 5314.1 1576.1 True False 2305.7037231997087 4919.358353094427 6432.8105484101925 5969.309193387816 5498.464609865147 4623.799941779097 5866.620125243017 4797.184595058219 5391.808659210513 1861.8344535992642 1.238404262388831 2.64221039823622 3.4550926565863045 3.2061439092224644 2.9532510794585503 2.4834645920535263 3.150989130049546 2.576590300917673 2.8959656691212086 1.0 10.862509084954567 -10.743319221074282 5.790585410685097 0.999945736563258 2.7727670017831643 0.4463572186270168 0.5777268784081317 0.0004114593401269212 5.5392785773056744e-05 0.5686459641908136 0.13791275458464855 1.8058462802154926e-11 10.743319221074282 1.7728212652199062 QPPGTQQSHSS(ph)PGEITSSPQGLDNPALLR ddPTM_PC-9_AZD4547_30min_R2 3 QPPGTQQSHSSPGEITSSPQGLDNPALLR 29 0 Q5TDH0-2;Q5TDH0;Q5TDH0-3 Q5TDH0-2 DDI2 Protein DDI1 homolog 2 1 QPPGT(0.001)QQSHS(0.172)S(0.827)PGEITSSPQGLDNPALLR;QPPGTQQS(0.002)HS(0.294)S(0.704)PGEITSSPQGLDNPALLR;QPPGTQQSHS(0.264)S(0.736)PGEITSSPQGLDNPALLR 129.62 9.3163e-14 113510900.0 58940.2 73661.4 111286.0 77180.5 98451.5 97115.0 78683.0 103599.0 88347.0 94393.0 True False 77681.95756768069 97471.00702281285 109810.27492701937 59387.72815183824 84783.20862159126 91042.38369777157 85685.63457083183 87590.1550181877 93016.84205602479 91088.32980099293 0.8528200894384376 1.0700712949261952 1.205536155585788 0.6519795486599301 0.9307801428220617 0.9994955873785177 0.9406872950468546 0.9615957961854396 1.0211718917148356 1.0 16.47497860792658 -10.03496722496441 16.54121599645697 0.9999999999999986 0.9606635066434934 0.007879322436124103 0.1361289079045196 0.0 0.0 0.13296302006731464 0.03224826917874465 9.226410537643852e-11 10.03496722496441 -0.03933649335650513 QPPGTQQSHSS(ph)PGEITSSPQGLDNPALLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QPPGTQQSHSSPGEITSSPQGLDNPALLR 29 0 Q5TDH0-2;Q5TDH0;Q5TDH0-3 Q5TDH0-2 DDI2 Protein DDI1 homolog 2 1 QPPGTQQS(0.002)HS(0.251)S(0.747)PGEITSSPQGLDNPALLR;QPPGTQQS(0.001)HS(0.247)S(0.752)PGEITSSPQGLDNPALLR;QPPGTQQS(0.001)HS(0.194)S(0.805)PGEITSSPQGLDNPALLR 123.68 8.075099999999999e-14 75783000.0 37172.8 50503.7 49781.2 50747.1 62931.0 44436.4 56245.0 51110.7 46362.1 32976.1 True False 43465.420843733555 55517.37356867444 50968.17260425234 47903.904511318025 50600.12230396342 42106.07695818857 50917.06642146336 49769.09828126302 47040.05800402399 38954.40589133602 1.1158024323354099 1.4251885582221713 1.3084058513542454 1.2297429113653224 1.2989576184299492 1.08090666497762 1.3070939026383148 1.2776243698875749 1.2075670756022574 1.0 15.249498891356382 -13.763351750975323 0.24873946890854612 1.3536726281073043e-09 1.279958430958489 0.39155470969714845 0.09413780331672514 121.07883533555298 1.6986082727238991 61.24432510395856 0.1364992829077756 1.724440638717898e-14 13.763351750975323 1.2799584296048163 QPPGTQQSHSS(ph)PGEITSSPQGLDNPALLR ddPTM_PC-9_Lapatinib_30min_R1 4 QPPGTQQSHSSPGEITSSPQGLDNPALLR 29 0 Q5TDH0-2;Q5TDH0;Q5TDH0-3 Q5TDH0-2 DDI2 Protein DDI1 homolog 2 1 QPPGTQQS(0.001)HS(0.234)S(0.765)PGEITSSPQGLDNPALLR;QPPGTQQS(0.001)HS(0.054)S(0.945)PGEITSSPQGLDNPALLR;QPPGTQQS(0.004)HS(0.06)S(0.936)PGEITSSPQGLDNPALLR;QPPGTQQS(0.006)HS(0.244)S(0.751)PGEITSSPQGLDNPALLR 129.62 2.185e-13 101817200.0 35757.5 46524.3 62050.7 48675.0 54963.9 50264.5 47737.3 44018.9 67034.6 37795.3 True False 35247.59149287758 46416.57584179449 56949.1309686287 52254.72187504004 51731.031465185086 48114.80450727242 50208.903813597164 46064.17879289504 59484.45744236786 44328.16724592839 0.7951511123238494 1.0471124507422067 1.2847165697756107 1.1788153023592403 1.167001360064952 1.0854228247320972 1.1326636523238829 1.039162718759281 1.3419110497475304 1.0 15.435936094864042 -4.835419326696844 3.4250469176605027 1.1540309593543767 0.7702881243842273 0.5489140208042537 0.09814408662859499 0.19219656528805404 3.7293449113753336 0.02380362345701546 0.17775319678982396 1.4607660719762111e-05 4.835419326696844 -0.3837428349701494 QPPGVPNGPS(ph)SPTNESAPELPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QPPGVPNGPSSPTNESAPELPQR 23 0 Q8TF74-2;Q8TF74 Q8TF74-2 WIPF2 WAS/WASL-interacting protein family member 2 1 QPPGVPNGPS(0.485)S(0.485)PT(0.026)NES(0.003)APELPQR;QPPGVPNGPS(0.496)S(0.496)PT(0.007)NESAPELPQR 67.76 0.00080338 17313200.0 52563.0 54933.0 59513.0 76063.0 86609.0 80688.0 85977.0 72480.0 84958.0 73053.0 True False 61460.87773342779 60386.38520045051 60932.015624309315 71801.43670957319 69638.58817790868 76456.57923689397 77832.63614042432 70577.47679890797 86200.35002525491 86296.93061277011 0.7122023610458851 0.6997512515412061 0.706073961051086 0.8320277001711588 0.8069648327399914 0.8859710153535869 0.9019166219210437 0.8178445779908654 0.9988808340362814 1.0 16.397021626456755 -5.847471753734761 0.25599614408789145 1.0148654666091954 0.5339861628316592 0.8251691595583982 0.04429526471007064 2.2169394506356377 0.19782188269638276 0.06937951655171587 0.33181770754701545 1.4207846168757964e-06 5.847471753734761 -0.4808793037775362 QPPGVPNGPS(ph)SPTNESAPELPQR ddPTM_PC-9_Lapatinib_30min_R1 1 QPPGVPNGPSSPTNESAPELPQR 23 0 Q8TF74-2;Q8TF74 Q8TF74-2 WIPF2 WAS/WASL-interacting protein family member 2 1 QPPGVPNGPS(0.887)S(0.109)PT(0.004)NESAPELPQR 134.26 9.109100000000001e-07 11167000.0 17058.0 21046.0 19553.0 17596.0 29303.0 33223.0 22673.0 23993.0 35102.0 22916.0 True False 16814.74979194591 20997.269280062395 17945.427816762698 18890.06853853527 27579.4551519146 31802.129736595627 23846.89700015899 25107.8023707528 31148.443119553125 26877.000066349377 0.625618549333501 0.7812356002614838 0.6676871590007095 0.7028339655431288 1.0261359185858214 1.1832470014543262 0.8872603691368016 0.9341742868910562 1.1589255885202638 1.0 14.714084497170191 -6.260811559944796 8.02627330284777 1.0289541725289115 0.6982567716669064 0.765314159131091 0.09148648858327275 0.05860245421107634 41.80388016201646 0.02817312713300013 0.03415725385406566 5.485149135104499e-07 6.260811559944796 -0.33069740086200516 QPPGVPNGPSS(ph)PTNESAPELPQR ddPTM_PC-9_AZD4547_30min_R2 2 QPPGVPNGPSSPTNESAPELPQR 23 0 Q8TF74-2;Q8TF74 Q8TF74-2 WIPF2 WAS/WASL-interacting protein family member 2 1 QPPGVPNGPS(0.14)S(0.857)PT(0.003)NESAPELPQR;QPPGVPNGPS(0.062)S(0.913)PT(0.025)NESAPELPQR 97.441 4.5197e-06 28689000.0 56346.0 59096.0 75333.0 98697.0 91813.0 80495.0 67047.0 104378.0 80670.0 75605.0 True False 74262.85593039273 78197.62631473385 74334.03519829226 75943.9315034495 79066.34975774026 75461.63492511067 73014.05311275065 88248.7784678267 84934.05150893099 72958.09196237112 1.017883745763178 1.071815671318064 1.0188593643132937 1.0409254060895445 1.0837228281479665 1.0343148086168534 1.0007670314405754 1.2095817762523438 1.1641484751648465 1.0 16.154780379441085 -7.750775793586844 24.999997536952126 1.140148856639826 1.0405578695120585 0.3276949286043286 0.05521436824143708 192.9636652081253 452391.8194757974 0.024973710240789867 0.014224612255575569 1.775105650385865e-08 7.750775793586844 -0.09959098712776737 QPPGVPNGPSS(ph)PTNESAPELPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QPPGVPNGPSSPTNESAPELPQR 23 0 Q8TF74-2;Q8TF74 Q8TF74-2 WIPF2 WAS/WASL-interacting protein family member 2 1 QPPGVPNGPS(0.22)S(0.759)PT(0.013)NES(0.007)APELPQR;QPPGVPNGPS(0.255)S(0.736)PT(0.009)NESAPELPQR 101.66 0.00084103 5280100.0 21732.0 21145.2 27645.0 25699.0 34327.0 28979.0 36330.0 30552.0 30418.0 24174.0 True False 25410.798373434798 23244.355712241573 28304.161644246335 24259.168347282142 27600.87076843135 27459.29022538609 32888.55939357746 29750.042372519787 30862.805704797705 28556.554838721302 0.8898411771639549 0.8139761901783529 0.9911616371127258 0.8495131322489885 0.9665336355982937 0.9615757356049345 1.1516991310514169 1.0417938207370931 1.0807608228338959 1.0 14.801534317708553 -6.833531657339293 1.882458190323462 1.0704908135974838 0.8906712745642373 0.62973305497975 0.05990950780549727 0.20691143313133317 1.508715558408633 0.024213860156320148 0.021051121024327157 1.4671291385128492e-07 6.833531657339293 -0.17981953903324643 QPPGVPNGPSS(ph)PTNESAPELPQR ddPTM_PC-9_Lapatinib_30min_R1 1 QPPGVPNGPSSPTNESAPELPQR 23 0 Q8TF74-2;Q8TF74 Q8TF74-2 WIPF2 WAS/WASL-interacting protein family member 2 1 QPPGVPNGPS(0.084)S(0.896)PT(0.02)NESAPELPQR 84.169 2.091e-05 12514000.0 33684.0 34312.0 45149.0 35338.0 41710.0 48439.0 45317.0 37794.0 52826.0 44771.0 True False 33203.65998311094 34232.55267212299 41437.02350017995 37936.874404112255 39256.69980501512 46367.37688682405 47663.29252221605 39550.04721378033 46876.1795975589 52509.60769639239 0.6323349466842838 0.6519293168224316 0.7891322239496913 0.7224749158946518 0.7476098475539021 0.8830265340186433 0.90770612490199 0.7531963948856081 0.8927162409704971 1.0 15.680293796762289 -2.9744759618870598 0.13852173703323928 1.0391410900732212 5.563863534508801e-13 0.7620678007127191 0.05521885404948208 26.784046220197926 0.3632307173376333 0.29263501179426676 5.187827968340133 0.0010605326370177425 2.9744759618870598 -1.0391410900726648 QPPKEPSEVPT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 QPPKEPSEVPTPK 13 1 P17096-2 P17096-2 HMGA1 High mobility group protein HMG-I/HMG-Y 1 QPPKEPSEVPT(1)PK;QPPKEPSEVPT(1)PK;QPPKEPSEVPT(1)PK 95.197 0.002578 24180800.0 95006.0 99355.0 104598.0 120505.0 129751.0 122309.0 119981.0 120506.0 125363.0 132797.0 True False 125215.93175243866 131469.56075708 103210.96217688094 92724.43403369073 111737.31331528816 114660.99889502907 130659.0765660045 101884.56665239765 131989.432246363 128147.81745026103 0.9771210641261187 1.0259211851821688 0.8054055404957715 0.7235740403435319 0.8719408222356779 0.8947557685836772 1.019596581242737 0.7950550284786775 1.0299779962900502 1.0 16.96744938201286 -7.019708113664411 22.92275325682727 0.9459497401634875 0.876674240423405 0.12200623234924368 0.0995393232298166 715.3023190020017 831974.5732819473 0.04011148660384504 0.03160328587143116 9.556346457108782e-08 7.019708113664411 -0.06927549974008251 QPPKEPSEVPT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QPPKEPSEVPTPK 13 1 P17096-2 P17096-2 HMGA1 High mobility group protein HMG-I/HMG-Y 1 QPPKEPS(0.006)EVPT(0.994)PK;QPPKEPSEVPT(1)PK 63.54600000000001 0.032454000000000004 20229300.0 249668.0 271050.0 223735.0 321500.0 334640.0 271170.0 259093.0 265821.0 228544.0 228601.0 True False 291931.86123222584 297958.05269295577 229069.6909197127 303487.39731706365 269069.69423333975 256949.36783249726 234549.83536912058 258843.4804106307 231886.02363723057 270044.5516954803 1.0810507355150312 1.103366280942237 0.8482662934004553 1.123841956490556 0.9963900124774971 0.9515073206225986 0.868559776142472 0.9585213950271411 0.8586954344434257 1.0 18.04283791581613 -6.762689928209808 3.0190905908157877 0.9178374605993621 1.0324547229648486 0.30083375624064246 0.08043713032557308 0.32240358176106376 6.060313805087777 0.02896746898334306 0.026917366967171865 1.7270705227196424e-07 6.762689928209808 0.11461726236548653 QPPKEPSEVPT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 QPPKEPSEVPTPK 13 1 P17096-2 P17096-2 HMGA1 High mobility group protein HMG-I/HMG-Y 1 QPPKEPSEVPT(1)PK 76.574 0.037235000000000004 0.0 22888.0 29971.0 27646.0 35912.0 32897.0 33889.0 29111.0 33676.0 30027.0 24594.0 True False 22561.61292285484 29901.603990912747 25373.052596646114 38553.0882789201 30962.063137990477 32439.646469117455 30618.22513878304 35240.70990028221 26645.0430616723 28845.040130554928 0.7821661131598084 1.0366289613595865 0.8796331182694035 1.3365586632719448 1.073392964539267 1.1246178310826769 1.0614727870095704 1.2217251125593853 0.9237304902705883 1.0 14.816035650093928 -4.4325100317789445 1.104768615247176 1.1022310393433137 0.4095847909663514 0.33242570419080286 0.12575009595197367 3.547826553675101 2.148495052862231 0.03712868071720414 3.446250688671541 3.693941116160436e-05 4.4325100317789445 -0.6926462483769622 QPPMFSPLIS(ph)AR ddPTM_PC-9_Lapatinib_30min_R1 1 QPPMFSPLISAR 12 0 A0A087WVF7;Q9NZM3-4;Q9NZM3-3;Q9NZM3-2;Q9NZM3;F8W719;E7EPJ2 A0A087WVF7 ITSN2 Intersectin-2 1 QPPMFS(0.461)PLIS(0.539)AR 63.966 0.045337 1541200.0 4619.2 3980.2 4322.5 4771.2 5062.7 5629.8 4637.4 5811.0 5794.0 4468.5 True False 4553.329360942463 3970.9840914427587 3967.120735332517 5122.089964256616 4764.921939651162 5389.026577704786 4877.501881027531 6081.000274098471 5141.41870647515 5240.874271098017 0.8688110275899623 0.7576949734019849 0.7569578146932658 0.9773350207051401 0.9091845545557921 1.0282686244590504 0.9306656921585804 1.1603026440900364 0.9810230966288704 1.0 12.355591783708679 -6.144362483808508 1.0943450852124046 1.0288642573076423 0.7870730805635687 0.6033844064205078 0.07337802688223134 0.32915551930634585 0.8135221264932027 0.02998169653719592 0.051428603155014234 7.171954343523913e-07 6.144362483808508 -0.24179117674407358 QPPPAS(ph)SPTK ddPTM_PC-9_AZD4547_30min_R2 1 QPPPASSPTK 10 0 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 QPPPAS(0.633)S(0.353)PT(0.014)K 89.301 0.009437000000000001 64204000.0 109790.0 81379.0 123280.0 141540.0 127220.0 150370.0 126840.0 130670.0 125540.0 129770.0 True False 144700.9362261356 107683.17029691915 121645.22665027896 108910.13977120118 109557.69897704804 140967.34012906245 138128.514278361 110477.95399788221 132175.78810501035 125226.79179891359 1.1555110064505456 0.859905206785417 0.9713993699176944 0.8697031857694372 0.8748742773269587 1.1256963314641542 1.1030268546699231 0.8822229844815099 1.055491290691654 1.0 16.9341837288828 -6.748923284632675 24.99999743088279 1.0302851559138546 0.9386215083116504 0.15544117682531122 0.10049615534336712 430.8823701251493 860655.0470216759 0.03330069775126866 0.03308109017706165 1.7826936411686314e-07 6.748923284632675 -0.09166364760220425 QPPPAS(ph)SPTK ddPTM_PC-9_Lapatinib_30min_R1 3 QPPPASSPTK 10 0 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 QPPPAS(0.632)S(0.33)PT(0.039)K;QPPPAS(0.647)S(0.285)PT(0.068)K;QPPPAS(0.486)S(0.486)PT(0.029)K 111.52 0.0015829000000000001 116169400.0 149871.0 203968.0 218412.0 222208.0 227454.0 204581.0 193632.0 181451.0 218935.0 190649.0 True False 147733.81205702494 203495.72462775704 200455.00845470116 238549.9175841576 214075.60291176935 195831.54753160375 203657.3175113474 189881.87587944258 194276.2348122431 223602.42562617542 0.6606986111322886 0.9100783413144484 0.8964795792950264 1.0668485232936238 0.957393920536742 0.8758024291695307 0.9108010207895831 0.8491941683892653 0.8688467232329553 1.0 17.77057631297513 -4.758121000837198 4.838829197848347 0.9250095837164721 0.6413653352502219 0.6191666548774077 0.06255875969676765 0.13633569661318892 7.8857061676113664 0.01674082126999961 0.13334620523403007 1.7453358089177102e-05 4.758121000837198 -0.28364424846625025 QPPPAS(ph)SPTKR ddPTM_PC-9_AZD4547_30min_R2 2 QPPPASSPTKR 11 1 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 QPPPAS(0.482)S(0.482)PT(0.037)KR;QPPPAS(0.49)S(0.49)PT(0.021)KR 90.434 0.012837999999999999 6214100.0 8482.3 6867.1 8904.7 14735.7 12410.8 11196.099999999999 10576.9 12043.3 9366.8 9487.8 True False 11179.494957199626 9086.755781540372 8786.617859772383 11338.612029295526 10687.774646001795 10496.006097087176 11518.223609829685 10182.284712502433 9861.909925298794 9155.635009861562 1.2210507458148079 0.9924768486023089 0.9596950785290469 1.2384298868492105 1.1673438963534437 1.14639848418836 1.2580474863210878 1.1121330963428602 1.0771410082071315 1.0 13.160444235546247 -4.452413238732569 21.13976670917515 1.1161932686511693 4.459615372169482 0.10518894654387734 0.09666076163313024 607.3200084005517 187986.95128301697 0.024570283896742307 3042.064231656533 3.528472697124944e-05 4.452413238732569 3.343422103518313 QPPPAS(ph)SPTKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QPPPASSPTKR 11 1 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 QPPPAS(0.473)S(0.46)PT(0.067)KR;QPPPAS(0.668)S(0.295)PT(0.037)KR 114.87 0.00064895 23679500.0 38816.0 49572.0 42614.0 51104.0 51287.0 39481.0 47351.0 50904.0 46903.0 37832.0 True False 45386.78214905414 54493.18055006527 43630.07937449496 48240.80856140344 41237.68051681003 37410.5468576717 42865.57048844719 49567.82393724628 47588.86764324171 44690.64212205278 1.0155768633867501 1.2193420806360575 0.9762687959447672 1.079438698366762 0.9227363617687009 0.8371002313079614 0.9591621076148066 1.1091320595008152 1.064850836407177 1.0 15.447685153296602 -5.29103595210745 24.810868404316018 0.9912012999780588 1.11745950742014 0.23991186976563716 0.08811321728678269 818.3213179213013 685999.2024054865 0.02471161270761767 0.051452012445922256 5.116394788452974e-06 5.29103595210745 0.12625820744208127 QPPPAS(ph)SPTKR ddPTM_PC-9_Lapatinib_30min_R1 1 QPPPASSPTKR 11 1 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 QPPPAS(0.498)S(0.498)PT(0.004)KR 114.87 0.0020795 3637500.0 3321.2 2709.9 2775.0 3620.7 4228.4 3301.2 3142.6 3265.5 3571.4 2289.8 True False 3273.8390789665114 2703.625393045759 2546.850211809772 3886.9783563011288 3979.6938253542507 3160.0153714730604 3305.308451140104 3417.2270512938476 3169.1513234907425 2685.5888790332865 1.219039557590428 1.0067160369009889 0.9483395733774951 1.447346757594669 1.4818700868268395 1.1766564108690196 1.230757424170558 1.2724311892905678 1.180058253976506 1.0 11.391022752652924 -5.7498081977413324 24.999940892008315 1.2720448257146046 1.0529001628130679 0.2770685495850086 0.1444643213472351 269.7793742210344 579855.7729465343 0.039886971889767746 0.06835259393415721 1.7790649446236616e-06 5.7498081977413324 -0.21914466290153678 QPPPASS(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 2 QPPPASSPTK 10 0 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 QPPPAS(0.212)S(0.685)PT(0.103)K;QPPPAS(0.1)S(0.896)PT(0.004)K 111.94 0.0015236 59639400.0 101742.0 86558.0 111352.0 135316.0 130239.0 113243.0 136561.0 124034.0 105829.0 125116.0 True False 134093.83963493467 114536.18076605425 109875.39972389562 104120.9868113598 112157.56293878118 106161.89730820943 148714.66444628872 104867.39531777227 111422.90488581455 120735.72692234669 1.1106392701903347 0.9486519333231018 0.9100487695292042 0.8623875423247922 0.9289509062294153 0.8792914907158287 1.2317370196639241 0.868569709985012 0.9228660623170651 1.0 16.881493121755 QPPPASS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 QPPPASSPTK 10 0 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 QPPPAS(0.131)S(0.435)PT(0.435)K;QPPPAS(0.447)S(0.534)PT(0.019)K;QPPPAS(0.34)S(0.651)PT(0.009)K;QPPPAS(0.052)S(0.923)PT(0.025)K;QPPPAS(0.26)S(0.72)PT(0.02)K 107.97 0.0020959 90215300.0 275922.0 311126.0 287180.0 322623.0 366976.0 297220.0 329082.0 344348.0 288754.0 244424.0 True False 322630.1448920882 342012.5331198979 294027.4603362144 304547.479267879 295069.687159258 281633.2599740933 297908.9706126414 335309.2298668646 292976.4809811023 288736.1363406812 1.1173874838839546 1.184515860932473 1.0183258114574545 1.0547605267826328 1.0219354283078161 0.9754001128621906 1.0317689167286535 1.1612998432285997 1.0146858813523012 1.0 18.139392151657404 -5.26558157598374 24.986892564235305 1.0385605120371346 1.1509516757578733 0.46861802033321576 0.04935443873209439 292.5481712824363 1764742.1223845228 0.013362788166454932 0.029425185326473743 5.42523336537338e-06 5.26558157598374 0.11239116372073865 QPPPASS(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 1 QPPPASSPTK 10 0 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 QPPPAS(0.473)S(0.504)PT(0.023)K 93.62299999999999 0.006675399999999999 5239200.0 38120.0 38468.0 41388.0 40143.0 41408.0 40007.0 40557.0 34188.0 45195.0 42410.0 True False 37576.401809648174 38378.929709466895 37985.238402300136 43095.25013312236 38972.46285126027 38295.99387087202 42656.8430130749 35776.49928943011 40104.66317555134 49740.511992227126 0.7554486334101301 0.7715829245075787 0.7636680219181505 0.8664014182213643 0.7835155146241848 0.7699155544851746 0.8575875338746175 0.7192627871426183 0.8062776511391445 1.0 15.60213373722179 -8.568325343344105 22.307208618365177 1.0000000003954785 0.7875112062976771 0.693877002863396 0.042388669050064776 4635.2837564432975 2275198.281067029 0.040104427766921975 0.010354918716915814 2.701933504331224e-09 8.568325343344105 -0.21248879409780141 QPPPASS(ph)PTKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QPPPASSPTKR 11 1 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 QPPPAS(0.093)S(0.692)PT(0.215)KR 85.45 0.005252000000000001 14932000.0 33709.0 31184.0 34622.0 31689.0 38885.0 30331.0 35937.0 36559.0 23853.0 24368.0 True False 39415.267916901954 34279.74143212364 35447.5197846662 29913.56806712418 31265.763388308125 28740.38896532612 32532.787198651087 35599.36498746242 24201.80499955748 28785.725503018137 1.3692643568344083 1.1908590397879486 1.231427006449762 1.0391806197133295 1.0861551286949485 0.9984250340437916 1.1301708270385638 1.2367020238461552 0.8407571661523682 1.0 14.81306595332609 -1.5228787452805734 0.4606204293678446 1.0429820878967209 8.901236035188262 0.5069526770405035 0.10115511938821356 79.96135511694862 0.9399731914021148 0.06058219291169659 594.8950134976162 0.029999999999983706 1.5228787452805734 7.858253947291541 QPPPASS(ph)PTKR ddPTM_PC-9_Lapatinib_30min_R1 1 QPPPASSPTKR 11 1 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 QPPPAS(0.127)S(0.437)PT(0.437)KR 93.243 0.0033043 6220300.0 13006.0 14986.0 13673.0 16193.0 18992.0 17086.0 13465.0 11499.0 20547.0 12719.0 True False 12820.532054991709 14951.300837737104 12548.858719306314 17383.88723826446 17874.927899708622 16355.271609411337 14162.151815249004 12033.285519163355 18232.78049049791 14917.462202997807 0.8594311740515287 1.0022683908481764 0.8412194077344135 1.1653381119189965 1.1982552834031304 1.0963843170405076 0.9493673670849311 0.8066576844917462 1.2222441218476061 1.0 13.864714501029713 -5.752025427295601 24.99952498513676 1.0568918928943833 0.9111025364520422 0.2608707774030127 0.12406668545519377 326.71906621849837 867620.2777247836 0.03580694119297977 0.060980770605003155 1.77000532410602e-06 5.752025427295601 -0.14578935644234114 QPPPLAPQS(ph)PQGGVMGGSNSNQQQQMR ddPTM_PC-9_AZD4547_30min_R2 1 QPPPLAPQSPQGGVMGGSNSNQQQQMR 27 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8;H0YCI3;P46937-4 P46937-6 YAP1 Transcriptional coactivator YAP1 1 QPPPLAPQS(0.997)PQGGVMGGS(0.001)NS(0.001)NQQQQMR 49.744 0.010506999999999999 10543000.0 10984.0 8971.9 12910.0 18569.0 15197.0 8473.3 17150.0 18275.0 14821.0 13640.0 True False 14476.68351860706 11871.891219933013 12738.804964755846 14288.203938190143 13087.158869314564 7943.463211515504 18676.316776047715 15451.018667722474 15604.40780232882 13162.467751692882 1.0998456970004846 0.9019502606877132 0.9678128148209482 1.085526225608604 0.9942785134369174 0.6034934604488479 1.4189069351106804 1.173869441445374 1.1855229655033244 1.0 13.6841423761733 -7.281931758250913 24.998848435306403 1.2090639215252212 0.9503767141202119 0.3729244417868992 0.15970147982260877 891.535230386032 1087587.786649528 0.06574970584129451 0.04438692248012604 5.224782808333732e-08 7.281931758250913 -0.2586872074050094 QPPPLAPQS(ph)PQGGVMGGSNSNQQQQMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QPPPLAPQSPQGGVMGGSNSNQQQQMR 27 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8;H0YCI3;P46937-4 P46937-6 YAP1 Transcriptional coactivator YAP1 1 QPPPLAPQS(0.979)PQGGVMGGS(0.011)NS(0.01)NQQQQMR 43.681000000000004 0.024059999999999998 9621600.0 16223.0 17092.0 20692.0 18175.0 19590.0 16915.0 16636.0 14167.0 13234.0 15081.0 True False 18969.23348114452 18788.780802907193 21185.375754846984 17156.71367414503 15751.480127991665 16027.947622844325 15060.117645790104 13795.131261177276 13427.522213731765 17815.06591886968 1.0647860393854816 1.0546568218423573 1.1891831246275366 0.9630451973782861 0.8841662556694628 0.8996850023365648 0.8453585136521139 0.774351962771325 0.7537172343274555 1.0 14.12081020125532 -6.086503486582999 2.51292888449509 0.8465625543602887 1.0977611658267081 0.6774089696029301 0.0742061199288176 0.16482968819395952 2.045597873910175 0.023711657663374557 0.033844148444194665 8.194010448760638e-07 6.086503486582999 0.2511986114664194 QPPVS(ph)PGTALVGSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QPPVSPGTALVGSQK 15 0 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 QPPVS(0.876)PGT(0.124)ALVGSQK;QPPVS(0.883)PGT(0.117)ALVGSQK 161.48 0.00014972 25054000.0 71018.0 232380.0 126831.0 60272.0 85940.0 41510.0 63995.0 39321.0 35572.0 39407.0 True False 83039.94473056278 255449.15065408233 129855.13204924634 56895.155244460446 69100.6739254518 39333.142525821364 57932.930316322316 38288.865414043314 36092.173204387655 46551.17715435961 1.7838419951274191 5.487490677347115 2.78951339122227 1.2222065847186014 1.4844022890402975 0.8449441008848416 1.2444997926523278 0.8225112178598792 0.7753224603689222 1.0 15.506530029681196 -5.662602942667007 3.5436215291713307 1.053502536224056 3.7369067519498174 0.6070560945372432 0.8605672164392641 0.13405650257469406 3.249139177401429 0.22478436261391674 0.4108123133060811 2.174688497264017e-06 5.662602942667007 2.683404215725761 QPPVS(ph)PGTALVGSQK ddPTM_PC-9_Lapatinib_30min_R1 2 QPPVSPGTALVGSQK 15 0 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 QPPVS(0.958)PGT(0.042)ALVGSQK;QPPVS(0.963)PGT(0.037)ALVGSQK 129.88 1.391e-05 25496000.0 36602.0 113618.0 110334.0 93084.0 129105.0 131195.0 165365.0 171107.0 103836.0 110463.0 True False 36080.04876801527 113354.92450166907 101262.7644215563 99929.70787912115 121511.29773019605 125584.09568048232 173926.79056284094 179057.25587681387 92140.89623844567 129556.38236730474 0.2784891651707662 0.8749466636101108 0.78161154681262 0.771322153746242 0.9379028304888901 0.9693393207324931 1.3424795242409735 1.3820797756545056 0.7112030650656592 1.0 16.98322056353917 -4.788613351359543 0.5290121231128924 1.1182710100169617 1.416237196020371e-15 0.5028016738363186 0.21122066216737245 3.7133363370004693 0.7994888283562196 0.1298665858326922 2.586069731443012 1.6269966122325397e-05 4.788613351359543 -1.1182710100169604 QPPVSPGTALVGS(ph)QKEPSEVPTPK ddPTM_PC-9_AZD4547_30min_R2 1 QPPVSPGTALVGSQKEPSEVPTPK 24 1 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 QPPVS(0.252)PGT(0.332)ALVGS(0.412)QKEPS(0.003)EVPTPK 44.75899999999999 0.026168 12407000.0 56007.0 47606.0 60564.0 69330.0 64392.0 61432.0 49418.0 65373.0 42136.0 57847.0 True False 73816.0609820307 62993.70851393031 59760.881788185354 53347.039637822265 55452.28228682659 57590.647328646526 53816.10626464875 55271.104972094196 44363.22293765112 55821.79413725646 1.322351997510674 1.1284787507732073 1.0705654075045195 0.9556668763933099 0.9933805092412239 1.0316875016062856 0.9640698063613637 0.990134871627232 0.7947294353988223 1.0 15.768540873557981 -1.522878745282331 0.5542189882139453 0.9486725283947368 18.212337670460286 0.7794894304216702 0.06043464519818724 61.77236129833418 0.558224926135037 0.029416629687028174 1271.5264197843148 0.029999999999862303 1.522878745282331 17.26366514206555 QPPVSPGTALVGSQKEPS(ph)EVPTPK ddPTM_PC-9_AZD4547_30min_R2 1 QPPVSPGTALVGSQKEPSEVPTPK 24 1 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 QPPVS(0.001)PGT(0.001)ALVGS(0.001)QKEPS(0.543)EVPT(0.453)PK 46.178000000000004 0.022841 9974400.0 41437.0 33303.0 39581.0 48936.0 46506.0 47767.0 42094.0 38276.0 38221.0 52387.0 True False 54613.10405685735 44067.543474339815 39056.13007823405 37654.56125366325 40049.44465199335 44780.1219388504 45840.28445311677 32361.323694979237 40241.284030282 50552.94707536179 1.0803149413909119 0.8717106721522315 0.772578698923549 0.7448539290405705 0.7922276933190393 0.8858063580763046 0.9067776876544977 0.6401471242959703 0.796022514182849 1.0 15.625507578642646 -4.788519406252219 3.0151579253251777 0.8069551640266402 1.1222892088461438 0.41275181503368263 0.09318042895297601 0.34923435858755375 4.668576984880876 0.023619245953020576 0.2669457518092361 1.6273485966825698e-05 4.788519406252219 0.31533404481950356 QPPVSPGTALVGSQKEPSEVPT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 QPPVSPGTALVGSQKEPSEVPTPK 24 1 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 QPPVSPGTALVGSQKEPS(0.007)EVPT(0.992)PK;QPPVS(0.019)PGT(0.044)ALVGS(0.044)QKEPS(0.179)EVPT(0.714)PK 57.483999999999995 0.0045398999999999995 22172000.0 64875.0 65357.0 82545.0 86462.0 99428.0 91280.0 88542.0 80066.0 86451.0 102876.0 True False 85503.90051617195 86482.3721242058 81450.39936605509 66529.52172458381 85624.13845220838 85572.24717018584 96422.06647141805 67693.6394336454 91020.62336678542 99274.34255301734 0.8612890130247773 0.8711452516345801 0.8204577061042394 0.6701582706433317 0.8625001813180573 0.8619774754437289 0.9712687487194787 0.6818845402828398 0.9168594928561322 1.0 16.599133281044423 -6.489410506224346 24.993910277201994 0.8707557141317684 0.8058382634546395 0.1284052799593779 0.09520738870279476 1612.571265840559 1204260.6326034043 0.02960196154869551 0.03354267305390348 3.2403318811341225e-07 6.489410506224346 -0.06491745067712895 QPPVSPGTALVGSQKEPSEVPT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QPPVSPGTALVGSQKEPSEVPTPK 24 1 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 QPPVS(0.006)PGT(0.006)ALVGS(0.003)QKEPS(0.28)EVPT(0.704)PK;QPPVSPGTALVGSQKEPS(0.167)EVPT(0.832)PK 53.895 0.007264100000000001 13835100.0 59727.0 49292.8 45848.8 68485.0 77554.0 65579.0 65433.0 73417.0 58542.0 48276.0 True False 69837.60143797816 54186.26341923375 46942.009274542266 64648.00748136573 62357.85042604718 62139.921794768496 59234.71254610391 71489.88154174163 59398.065999417035 57028.056647394274 1.2246182939353094 0.950168506604891 0.8231388554021004 1.1336175784681877 1.093459151371879 1.0896377230418528 1.0386942152413405 1.253591402978452 1.0415586553593537 1.0 15.799384250185584 QPPVSPGTALVGSQKEPSEVPT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 QPPVSPGTALVGSQKEPSEVPTPK 24 1 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 QPPVSPGTALVGSQKEPS(0.01)EVPT(0.99)PK;QPPVSPGTALVGSQKEPS(0.013)EVPT(0.987)PK 60.82899999999999 0.0027741 18870700.0 125216.0 93702.0 71159.0 92727.0 97828.0 91169.0 76209.0 79679.0 91097.0 73140.0 True False 123430.3968781976 93485.03877603394 65308.5817016834 99546.45290820434 92073.94937724812 87269.91439531905 80154.72912649917 83381.17722249051 80836.69656606269 85782.15154707621 1.4388820360895296 1.0897959201306635 0.7613306558980726 1.1604564715723462 1.0733462348134162 1.0173435011993885 0.9343986794561945 0.9720107938389949 0.9423486717012511 1.0 16.388389880966727 -4.804110968438082 3.8704952459590114 0.9873728975136173 1.4717464684819335 0.6603690031646138 0.09791340017837205 0.13735561347841307 3.6704080248679034 0.02475749658384533 0.1795617533102733 1.569961605484092e-05 4.804110968438082 0.4843735709683161 QPPVYCTS(ph)PDFK ddPTM_PC-9_AZD4547_30min_R2 1 QPPVYCTSPDFK 12 0 Q9NR48-2;Q9NR48 Q9NR48-2 ASH1L Histone-lysine N-methyltransferase ASH1L 1 QPPVYCT(0.059)S(0.941)PDFK 98.337 0.010912999999999999 0.0 16733.0 14733.0 15580.0 21582.0 21025.0 21761.0 21363.0 22190.0 18571.0 20630.0 True False 22053.745931978523 19495.1541304822 15373.399020208833 16606.6033385761 18106.04166791727 20400.28122995632 23264.26561438527 18761.045375472586 19552.62514655208 19907.749979283308 1.107797011461788 0.979274611684873 0.7722318713167949 0.8341778129551308 0.9094971398957211 1.0247406789408926 1.1686034654139652 0.9423990855318144 0.9821614781629876 1.0 14.281042553035613 -6.766749715396707 8.42832515690058 1.0292175657420537 0.9107077952237679 0.20781721256186259 0.09931120830669117 0.19530441335982018 119.79703059971713 0.036982982585393405 0.03430456357487232 1.7110010836692158e-07 6.766749715396707 -0.11850977051828582 QPS(ph)DASETTGLVQR ddPTM_PC-9_AZD4547_30min_R2 2 QPSDASETTGLVQR 14 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 QPS(0.82)DAS(0.173)ET(0.005)T(0.002)GLVQR;QPS(0.597)DAS(0.388)ET(0.012)T(0.004)GLVQR 144.15 0.00013453 12644700.0 9769.4 7818.4 14761.900000000001 19422.4 16910.3 16843.3 12848.1 20803.0 15016.0 18127.8 True False 12875.86598385651 10345.544902854945 14566.147560745883 14944.865753088714 14562.596738025273 15790.085788360988 13991.556009932285 17588.37435538334 15809.71510422842 17493.151239672883 0.7360518300816615 0.5914054455432927 0.8326771638326192 0.8543266760991074 0.8324741802379564 0.9026438731376485 0.7998305061354928 1.0054434512344752 0.9037659874781976 1.0 14.094502581235421 -3.1818558330891107 0.21989265990961468 1.003639399990517 2.4082468955711345e-10 0.6532447701456041 0.06845773198423565 14.650377003180546 0.3501845691869234 0.11064624477731798 4.495092238353652 0.0006578761874412332 3.1818558330891107 -1.0036393997496924 QPS(ph)DASETTGLVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QPSDASETTGLVQR 14 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 QPS(0.756)DAS(0.231)ET(0.011)T(0.002)GLVQR 106.35 0.00088389 4462600.0 7304.4 5836.0 5754.8 4937.4 6167.8 6143.8 4915.8 4772.2 1538.5 2572.7 True False 8540.890651523892 6415.359511219655 5892.016257200535 4660.7734852667745 4959.263865922764 5821.608312458231 4450.139836690011 4646.934806563859 1560.997651943956 3039.1101445180066 2.8103261301437468 2.110933531906298 1.938730739268744 1.533598080896788 1.6318144555794927 1.9155634497023206 1.4642904090584679 1.5290445510657358 0.5136364191208099 1.0 11.56943324714004 -1.5228787452803652 0.19982737748562357 0.8615831151301325 9.284981040140938 0.7445321973809369 0.2985619536607529 28.676607282864662 0.34628330557309484 0.5689586720579533 75.6058954787119 0.029999999999998094 1.5228787452803652 8.423397925010805 up QPS(ph)DASETTGLVQR ddPTM_PC-9_Lapatinib_30min_R1 3 QPSDASETTGLVQR 14 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 QPS(0.999)DAS(0.001)ETTGLVQR;QPS(0.979)DAS(0.019)ET(0.001)TGLVQR;QPS(0.963)DAS(0.022)ET(0.012)T(0.004)GLVQR 164.53 0.00024631 19235300.0 27739.8 23991.199999999997 33031.0 28840.2 31988.9 33822.0 24156.6 20852.5 26912.1 23625.4 True False 27344.225365143717 23935.64985041493 30315.31868334724 30961.204516086873 30107.375794597156 32375.51190293285 25407.310548848433 21821.3832757939 23880.975901023445 27709.018911133313 0.9868348443819126 0.8638216288775831 1.0940596193814256 1.1173692080323656 1.0865550993037938 1.168410617740225 0.9169328813240635 0.787519159223144 0.8618484825324586 1.0 14.758068009997073 -7.473835786677846 8.50745154182491 0.8651991628933011 1.0501807178289282 0.42364664700116506 0.09203557310704003 0.34095508621315257 56.19184375349398 0.041631925499483094 0.0277820985904438 3.3586458572394764e-08 7.473835786677846 0.18498155493562707 QPS(ph)EEEIIK ddPTM_PC-9_AZD4547_30min_R2 3 QPSEEEIIK 9 0 B1AKZ5;Q15121;Q15121-2 B1AKZ5 PEA15 Astrocytic phosphoprotein PEA-15 1 QPS(1)EEEIIK;QPS(1)EEEIIK;QPS(1)EEEIIK 124.48 0.0014572 844680000.0 97336.0 96442.0 133912.0 160949.0 164265.0 146653.0 139670.0 171009.0 158276.0 125629.0 True False 128286.82328542763 127614.99047389964 132136.2393834536 123844.6946872618 141459.64017029403 137482.76472665727 152100.3594233579 144583.4884458849 166642.14623314177 121230.76694849171 1.05820351148924 1.0526617432695153 1.0899563098499192 1.0215615870835881 1.1668625360622946 1.1340583598309717 1.254634968101637 1.1926303205465594 1.3745862574963694 1.0 16.887396358817348 -6.647506324259123 1.492582230813828 1.2183319630471432 1.057306458450087 0.3223770440983479 0.09086661466322034 0.4113866205761464 1.9009721838862121 0.03664293843870688 0.03652664833643921 2.2516126281968025e-07 6.647506324259123 -0.1610255045970561 QPS(ph)EEEIIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 QPSEEEIIK 9 0 B1AKZ5;Q15121;Q15121-2 B1AKZ5 PEA15 Astrocytic phosphoprotein PEA-15 1 QPS(1)EEEIIK;QPS(1)EEEIIK;QPS(1)EEEIIK;QPS(1)EEEIIK;QPS(1)EEEIIK;QPS(1)EEEIIK;QPS(1)EEEIIK 153.75 5.5727e-05 1049549900.0 200849.6 209710.1 222362.0 285883.0 281508.0 257147.1 250434.1 218518.2 213439.0 212125.9 True False 234849.4703195757 230528.73280223174 227663.95339258134 269865.90235519124 226348.52822208652 243661.85339440213 226711.1690621278 212782.3287891715 216560.14158808332 250582.64648229923 0.9372136243926417 0.9199708600671832 0.9085383867899375 1.0769536763362988 0.9032889204403682 0.9723811956452221 0.9047361109985815 0.8491502974217415 0.86422641243587 1.0 17.934926982070216 -7.395849956852985 5.232641930239321 0.8898035409186225 0.9526949569971953 0.12122860945101388 0.06001474646210387 0.39108182288048127 14.999207533198156 0.025404638792432786 0.01680056321983295 4.0192964837836753e-08 7.395849956852985 0.06289141607857285 QPS(ph)EEEIIK ddPTM_PC-9_Lapatinib_30min_R1 7 QPSEEEIIK 9 0 B1AKZ5;Q15121;Q15121-2 B1AKZ5 PEA15 Astrocytic phosphoprotein PEA-15 1 QPS(1)EEEIIK;QPS(1)EEEIIK;QPS(1)EEEIIK;QPS(1)EEEIIK;QPS(1)EEEIIK;QPS(1)EEEIIK;QPS(1)EEEIIK 136.93 0.00097362 1042812500.0 1295736.7 966918.4 1298043.0 1274787.7 1447063.5 1408672.4 1217417.2 1295892.5 1559196.4 1736723.9 True False 1277259.2570489927 964679.5598520879 1191322.9151308774 1368539.8400251067 1361950.069966302 1348426.7652277488 1280449.1057478918 1356104.3964381595 1383583.282366018 2036914.3120758706 0.6270559588475303 0.4735984985391745 0.5848664855797348 0.671869126703908 0.6686339537662261 0.6619948405456159 0.6286219789201412 0.6657640865884631 0.6792545342547932 1.0 20.957953860308685 -14.522878745279941 0.1703552979153969 2.461371555912 0.54032962888703 0.8476834398333454 0.04910424018982813 51.343578510277545 0.4831073446142232 25.30871544898585 0.18988565790165543 3.0000000000027376e-15 14.522878745279941 -1.9210419270249703 QPS(ph)EPKR ddPTM_PC-9_AZD4547_30min_R2 1 QPSEPKR 7 1 Q9UL26 Q9UL26 RAB22A Ras-related protein Rab-22A 1 QPS(1)EPKR 68.37100000000001 0.037561000000000004 0.0 69398.0 76704.0 87580.0 137640.0 95929.0 90870.0 83506.0 87392.0 79391.0 82743.0 True False 91465.12043192754 101497.06797152688 86418.63197624465 105909.22451680164 82610.9142050719 85187.8845349999 90937.8722274427 73887.57446837766 83587.44618006126 79846.19275500896 1.145516364350255 1.2711572646043252 1.0823137458964616 1.32641546030581 1.0346255889563312 1.0668997681126862 1.1389130663557898 0.9253737957811707 1.0468557522402044 1.0 16.284935997900824 -6.776601786143707 0.9285571026315573 1.004554913876931 1.2035603776612733 0.44652822329684805 0.0857975015889898 0.5042225256345126 0.9380979035293208 0.05025571084182811 0.045575893595723616 1.672623575566362e-07 6.776601786143707 0.19900546378434236 QPS(ph)MSETMPLYTLCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QPSMSETMPLYTLCK 15 0 K7EJD2;A0A0A0MR03;Q9Y5B0 K7EJD2 CTDP1 RNA polymerase II subunit A C-terminal domain phosphatase 1 QPS(0.984)MS(0.015)ETMPLYTLCK 80.387 0.038110000000000005 0.0 7901.8 9454.6 10316.0 9324.2 15565.0 12573.0 19009.0 14730.0 15425.0 14814.0 True False 9239.418672336053 10393.190204725386 10561.972563647862 8801.795303464272 12515.149984287407 11913.649746498479 17208.32990675789 14343.353107725085 15650.561443766997 17499.660932440525 0.5279770109835786 0.5939080902681203 0.603552983364854 0.5029694768055579 0.7151652842077111 0.6807931760788114 0.9833521902620083 0.8196360582698868 0.8943351247882921 1.0 14.095039348702736 -6.922389176790403 1.4067830379228965 0.9163147872950219 0.5651049033484048 0.8373920693697976 0.07002903246550032 0.15731442162449014 0.6410703356675487 0.03360380410410266 0.026410827568540136 1.1956685973056673e-07 6.922389176790403 -0.3512098839466171 QPS(ph)PSHDGS(ph)LSPLQDR ddPTM_PC-9_Lapatinib_30min_R1 1 QPSPSHDGSLSPLQDR 16 0 A0A0B4J2A3;Q96A00-2;Q96A00 A0A0B4J2A3 PPP1R14A Protein phosphatase 1 regulatory subunit 14A 2 QPS(0.99)PS(0.011)HDGS(0.926)LS(0.073)PLQDR 75.064 0.028187 5187500.0 13667.0 10971.0 15108.0 12191.0 16039.0 16123.0 13585.0 14596.0 15562.0 13631.0 True False 13472.106073779156 10945.597323556234 13865.878558566501 13087.566807983827 15095.617553887247 15433.456874548692 14288.3648280845 15274.183445317722 13809.24368487509 15987.100187834196 0.8426860353343572 0.6846518252187832 0.8673166737966718 0.8186329386953586 0.9442373774184923 0.9653693723826906 0.8937433718566177 0.9554067508090688 0.8637741380631114 1.0 13.964620659579499 -5.9310625824857794 1.5502724265283776 0.9343795801178326 0.7726163589880866 0.5628832327362314 0.0573731916965909 0.27055575240740193 1.3206937972033923 0.018285247970062223 0.03380749598889206 1.1720264626088994e-06 5.9310625824857794 -0.16176322112974606 QPS(ph)PSHDGSLS(ph)PLQDR ddPTM_PC-9_Lapatinib_30min_R1 1 QPSPSHDGSLSPLQDR 16 0 A0A0B4J2A3;Q96A00-2;Q96A00 A0A0B4J2A3 PPP1R14A Protein phosphatase 1 regulatory subunit 14A 2 QPS(0.987)PS(0.014)HDGS(0.223)LS(0.776)PLQDR 106.47 0.0022659000000000004 5708700.0 20568.0 17763.0 22004.0 13991.0 20061.0 20070.0 18813.0 19827.0 18186.0 18516.0 True False 20274.69654829075 17721.870864855475 20194.91605789631 15019.944812607802 18881.051421443502 19211.652885455074 19787.04508728403 20748.23480202207 16137.701172930123 21716.465928980837 0.9336093918133322 0.8160568539471915 0.9299356591417572 0.6916385410834062 0.8694348096596396 0.8846583485675233 0.9111540133644869 0.9554148851785939 0.7431089950687696 1.0 14.406501722029883 -6.63208612076242 4.57621375113085 0.8965338948382674 0.840091722298581 0.07934449971674318 0.08817267208467637 0.5851059147144195 20.916097804294573 0.02884948240576717 0.02875789173381077 2.332995382528102e-07 6.63208612076242 -0.05644217253968642 QPS(ph)PSHDGSLSPLQDR ddPTM_PC-9_Lapatinib_30min_R1 1 QPSPSHDGSLSPLQDR 16 0 A0A0B4J2A3;Q96A00-2;Q96A00 A0A0B4J2A3 PPP1R14A Protein phosphatase 1 regulatory subunit 14A 1 QPS(0.614)PS(0.383)HDGS(0.003)LSPLQDR 65.51100000000001 0.016056 4827100.0 11675.0 12829.0 11489.0 13429.0 11521.0 12529.0 10456.0 11690.0 12133.0 11609.0 True False 11508.512359067216 12799.29523871141 10544.418768822516 14416.61345783077 10843.3574311575 11993.163876525501 10997.360518399073 12233.160076443142 10766.453773845878 13615.60018197984 0.8452445874768457 0.940046348867617 0.7744365748032163 1.058830552097958 0.7963921741407047 0.8808398980750314 0.8077029562717337 0.8984664585431681 0.7907439723513041 1.0 13.732972958000309 QPS(ph)PSPSPTER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QPSPSPSPTER 11 0 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BT57;P29590-14;P29590-10;P29590-2 P29590;P29590-2 PML Protein PML 1 QPS(0.504)PS(0.436)PS(0.03)PT(0.03)ER 92.781 0.020022 0.0 4490.8 7648.6 7987.3 5823.7 4973.5 6973.2 6430.4 7358.7 5530.7 5633.0 True False 5251.003742656955 8407.90246016358 8177.747524003933 5497.416969690145 3998.9783775684796 6607.513116382976 5821.265959935608 7165.541922187141 5611.576024443576 6654.218309196534 0.7891240561494276 1.2635447274916345 1.2289569028268563 0.8261551867170305 0.6009689180232708 0.9929811150396118 0.874823411172168 1.076842025498912 0.8433110793326448 1.0 12.700053483078346 -5.771025359419358 24.9951800175064 0.8829525125711665 1.1108421886591195 0.23388051181848235 0.1698674632828755 261.8684360776095 682815.3078654093 0.04865728657158323 0.07322483748080326 1.6942388671885627e-06 5.771025359419358 0.22788967608795307 QPS(ph)PSPSPTER ddPTM_PC-9_Lapatinib_30min_R1 1 QPSPSPSPTER 11 0 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BT57;P29590-14;P29590-10;P29590-2 P29590;P29590-2 PML Protein PML 1 QPS(0.89)PS(0.106)PS(0.003)PTER 90.79299999999999 0.0085439 5051200.0 1942.3 7120.3 7711.6 2412.5 7001.6 8527.6 6408.5 3907.6 6095.8 5756.1 True False 1914.6024458258034 7103.813382819924 7077.58201563684 2589.9232978640784 6589.779653675228 8162.894426806516 6740.300772968674 4089.1613613951395 5409.22681238026 6751.034215478862 0.2836013542096968 1.0522555738989154 1.0483700407574983 0.383633561199537 0.9761140950176332 1.209132433085663 0.998410103968133 0.6057088782070539 0.8012441708528023 1.0 12.720892815455166 -4.751784135877529 24.887226497811557 0.8889367384724751 0.2836000733655856 0.3896741398609459 0.2301686554827399 422.2342114568122 1088264.4745742131 0.06011961692009213 0.7636622873604217 1.7709890017209684e-05 4.751784135877529 -0.6053366651068894 QPS(ph)SPSHNTNLR ddPTM_PC-9_AZD4547_30min_R2 1 QPSSPSHNTNLR 12 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 QPS(0.498)S(0.498)PS(0.004)HNTNLR 70.27199999999999 0.036926 0.0 8494.3 7820.7 20529.0 32047.0 27523.0 19546.0 11965.0 21035.0 11090.0 16775.0 True False 11195.310707584114 10348.588332875992 20256.772046589693 24659.059271214373 23701.906531561817 18323.78553011011 13029.861820723676 17784.524086212976 11676.194759316282 16187.712355912618 0.6915931332011215 0.639286645657262 1.2513671852583195 1.523319585191886 1.4641912340939647 1.1319564572950473 0.8049229893786983 1.0986434460405468 0.7212998663799157 1.0 13.982611498236674 -7.238492834602261 21.374502146159855 0.9144369588784574 1.1356050444612011 0.11453843726337876 0.28385427640655186 318.77461445823633 296934.847293382 0.1236825492589075 0.09566679761095738 5.774403997887579e-08 7.238492834602261 0.2211680855827437 QPS(ph)SPSHNTNLR ddPTM_PC-9_Lapatinib_30min_R1 2 QPSSPSHNTNLR 12 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 QPS(0.66)S(0.339)PS(0.001)HNT(0.001)NLR;QPS(0.591)S(0.375)PS(0.033)HNTNLR 88.163 0.0081846 11394600.0 15958.8 9532.7 22839.1 12933.400000000001 19679.8 27574.4 15108.3 15844.0 31860.0 12516.099999999999 True False 15731.224585514505 9510.627618837343 20961.357359475514 13884.56538055763 18522.27285597546 26395.107191065912 15890.533848520357 16580.170081365697 28271.591299326596 14679.491208345067 1.0716464462045894 0.64788537176484 1.427934869265721 0.9458478624016932 1.2617789399571173 1.79809414484752 1.0824989519723156 1.1294785252461694 1.9259244682305219 1.0 13.841514344738883 -5.690522702159449 1.0267606604800397 1.3738770019755724 0.8735266005558823 0.19766461138282132 0.3323465228129462 1.0378869633959669 2.008781900812803 0.1244911499056695 0.41243738164658617 2.0392820560979016e-06 5.690522702159449 -0.5003504014196901 QPS(ph)SPYEDKDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QPSSPYEDKDK 11 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QPS(0.868)S(0.132)PYEDKDK 76.357 0.0097685 16448000.0 28031.0 45203.0 32400.0 31221.0 38023.0 26477.0 37248.0 22438.0 25531.0 24003.0 True False 32776.094662513846 49690.45510378033 33172.53887768426 29471.78858984768 30572.666100389335 25088.49950990537 33719.599787832994 21849.026275026175 25904.342575093375 28354.553892356562 1.155937588965178 1.7524682381680925 1.1699192660063844 1.0394023020687442 1.0782277237178013 0.8848137623730483 1.1892128479906245 0.770564980777777 0.9135866737115662 1.0 14.791292837832037 -5.516162646579994 4.187052533818655 0.9852435925717871 1.4613175385424322 0.5408601229551646 0.17211667180362128 0.1384456955269765 5.744889749613285 0.04475719771830037 0.08959787397058959 3.046753743535262e-06 5.516162646579994 0.4760739459706451 QPS(ph)SPYEDKDK ddPTM_PC-9_Lapatinib_30min_R1 1 QPSSPYEDKDK 11 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QPS(0.775)S(0.225)PYEDKDK 201.09 0.00018817 13082000.0 10108.0 31313.0 19040.0 25621.0 33420.0 27362.0 33552.0 37737.0 20802.0 24643.0 True False 9963.858066419827 31240.49667236497 17474.604696525435 27505.253809150494 31454.301306248006 26191.791043937334 35289.158388803145 39490.39878569158 18459.059705228865 28902.509715266522 0.34474023759801187 1.0808921778811307 0.6046050972277753 0.9516562430086136 1.0882896196946388 0.9062116508900483 1.2209721140639613 1.3663311309201793 0.6386663264567177 1.0 14.818907152433278 -4.4759795664844715 0.630966554329316 1.0630048992036345 1.9958214988880636e-12 0.33802077144566434 0.2387588200153507 5.846730610193648 1.340691088571806 0.10887082502532228 4.895422110275565 3.342107642419948e-05 4.4759795664844715 -1.0630048992016388 QPS(ph)VTPEK ddPTM_PC-9_Lapatinib_30min_R1 1 QPSVTPEK 8 0 A0A087X0C1;Q5JYT7 A0A087X0C1 KIAA1755 Uncharacterized protein KIAA1755 1 QPS(0.99)VT(0.01)PEK 85.212 0.013396000000000002 2428700.0 7590.8 7540.4 6801.4 6118.2 8205.9 9021.6 6498.6 6758.8 5594.4 4684.3 True False 7482.5538000177685 7522.940667080791 6242.215146163241 6568.152837716892 7723.245095420127 8635.767198376761 6835.065710105992 7072.838522212479 4964.299760356328 5493.9750135625945 1.36195628512072 1.369307404658636 1.1361928532171184 1.1955192408961723 1.4057663306357033 1.5718613894417508 1.244102074223625 1.2873809044912388 0.9035897957492173 1.0 12.423634633755997 -8.217377629385517 5.470889963476488 0.9508179298651671 1.3230969988826915 0.6179141641586146 0.11636954013187199 0.12964413957208992 9.780577998610372 0.09348918682276343 0.03254965775438232 6.062089872149811e-09 8.217377629385517 0.3722790690175244 QPSPS(ph)PSPTER ddPTM_PC-9_AZD4547_30min_R2 2 QPSPSPSPTER 11 0 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BT57;P29590-14;P29590-10;P29590-2 P29590;P29590-2 PML Protein PML 1 QPS(0.005)PS(0.489)PS(0.475)PT(0.031)ER;QPS(0.002)PS(0.966)PS(0.032)PTER 114.87 0.0014156 17394500.0 18292.3 18701.8 26542.0 27704.0 24645.1 23454.6 24139.0 29911.0 25074.0 23376.3 True False 24108.870896523662 24746.791116368127 26190.035737765294 21317.27082253324 21223.553270391814 21987.980154226996 26287.3242365607 25288.94223640202 26399.36045041446 22557.902852191957 1.0687549748970124 1.0970342091868472 1.1610137657464201 0.9450023329833533 0.9408477999686711 0.9747351204719998 1.1653266001190512 1.1210679646111115 1.1702932060392852 1.0 14.46134533002655 -7.267689316446443 24.826772599996453 1.1242609388448714 1.0320937598190072 0.20978532512148607 0.07787089954534707 747.8235918227192 2970582.759410423 0.03468727561950708 0.024068618498338634 5.398967131822464e-08 7.267689316446443 -0.09216717902586424 QPSPS(ph)PSPTER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QPSPSPSPTER 11 0 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BT57;P29590-14;P29590-10;P29590-2 P29590;P29590-2 PML Protein PML 1 QPS(0.356)PS(0.638)PS(0.005)PT(0.001)ER 90.689 0.008600700000000001 9783200.0 10245.0 19433.0 33386.0 19629.0 21256.0 22581.0 18598.0 14937.0 20017.0 10479.0 True False 11979.276152026485 21362.17981177716 34182.048857110065 18529.25076807662 17091.03938747273 21396.81260842138 16836.262802140212 14544.919577059714 20309.710756556495 12378.759748281635 0.9677283019964416 1.7257124498876042 2.7613468192445585 1.4968584207839377 1.3806746180565654 1.728510209707527 1.3600928642691648 1.1749900533515707 1.6406902766955955 1.0 13.595579154954818 -7.004136950566095 0.9890840317483655 1.277103892158469 1.7736863721987435 0.1413228215129868 0.45217415617628975 1.1114645020629839 2.245345733240841 0.3094432834226926 0.22196223397464576 9.905195448770921e-08 7.004136950566095 0.4965824800402745 QPSPS(ph)PSPTER ddPTM_PC-9_Lapatinib_30min_R1 3 QPSPSPSPTER 11 0 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BT57;P29590-14;P29590-10;P29590-2 P29590;P29590-2 PML Protein PML 1 QPS(0.078)PS(0.919)PS(0.003)PTER;QPS(0.082)PS(0.893)PS(0.025)PTER;QPS(0.052)PS(0.895)PS(0.052)PT(0.002)ER 126.09 0.00042842 37064600.0 17515.2 27057.0 35759.0 27018.899999999998 33069.4 29695.4 28519.5 32678.5 33531.4 26957.1 True False 17265.4300361057 26994.351178877114 32819.03305373177 29005.960038408197 31124.322908941886 28425.396965358384 29996.100163014777 34196.86240872942 29754.740630704324 31616.5988169221 0.5460875199157966 0.8538031347138129 1.0380317390802358 0.9174282220035441 0.9844298271667118 0.8990656183467878 0.9487453200361329 1.0816110425649674 0.9411113701066018 1.0 14.94839455642092 -4.803701024019964 2.8113591552250896 0.9733847546970136 0.47944764948081353 0.8587309586461527 0.05268710460630586 0.13659918799502196 1.5491588472340576 0.013510992134028335 0.15422014336560974 1.571444241978744e-05 4.803701024019964 -0.49393710521620005 QPSS(ph)PSHNTNLR ddPTM_PC-9_AZD4547_30min_R2 2 QPSSPSHNTNLR 12 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 QPS(0.212)S(0.748)PS(0.039)HNTNLR;QPS(0.326)S(0.671)PS(0.004)HNTNLR 80.507 0.008057600000000002 20219800.0 12729.8 7121.900000000001 31831.0 54554.0 36146.0 31175.0 21305.2 38973.0 18928.9 28802.0 True False 16777.61160371124 9423.91489865479 31408.90014199409 41977.418150898 31127.75182537635 29225.622321763163 23201.3215263587 32950.618360445864 19929.44300988475 27793.65074664651 0.6036490764256859 0.33906718424861293 1.1300746500811445 1.5103240136944893 1.119959090985272 1.0515215359137169 0.834770564610268 1.1855448088057154 0.7170502065940141 1.0 14.76246772715586 -5.2663838729875065 24.867409058827644 1.0839233959110597 0.4713581087647656 0.56652258035469 0.2086482317860259 246.55576610642967 1240012.8856089704 0.05643289799851359 0.12369133530165843 5.415220273608475e-06 5.2663838729875065 -0.6125652871462941 QPSS(ph)PSHNTNLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QPSSPSHNTNLR 12 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 QPS(0.033)S(0.962)PS(0.005)HNTNLR;QPS(0.225)S(0.77)PS(0.005)HNTNLR;QPS(0.286)S(0.358)PS(0.172)HNT(0.184)NLR 120.9 0.00047175 14933200.0 11957.4 13818.5 38297.3 32084.6 52081.0 52089.0 38905.5 36746.0 44965.0 28332.9 True False 13981.551650584808 15190.30935671501 39210.45287531906 30287.003881676683 41876.10191658671 49357.36114255617 35220.08938857219 35781.45643560528 45622.52805957748 33469.43048688702 0.4177409488955194 0.45385622449316604 1.1715303279714102 0.904915424047709 1.2511746183728265 1.4746997610817991 1.052306205280997 1.06907873588181 1.3631103785124734 1.0 15.030556382001015 -5.255719270293645 6.68195681466048 1.1655419782118441 0.4307387616341671 0.7638887410819718 0.16123509700003297 0.062482958344982575 16.493416379206888 0.042999959857220035 0.10418030563042961 5.5498434115466766e-06 5.255719270293645 -0.734803216577677 QPSS(ph)PSHNTNLR ddPTM_PC-9_Lapatinib_30min_R1 1 QPSSPSHNTNLR 12 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 QPS(0.091)S(0.908)PSHNTNLR 96.70700000000001 0.0023799 9816100.0 8211.4 5370.9 14257.0 6720.7 12646.0 18637.0 9423.6 9734.8 21091.0 8342.8 True False 8094.30393021366 5358.464011037115 13084.844493611508 7214.962697597974 11902.18714299259 17839.93895496893 9911.50789797108 10187.114346634613 18715.50948192396 9784.841863917763 0.8272288957537401 0.5476290864543041 1.337256613401461 0.7373611958107994 1.216390342176369 1.82322200022004 1.0129451283745734 1.0411118021437071 1.9127043382212043 1.0 13.256332819828406 -6.4182533275981095 5.359695307659979 1.3568111996153631 0.8776042705957825 0.310560156365561 0.3488024780024112 0.29450725700477703 12.378630379420938 0.10864880730389792 0.12285254311379681 3.817215445226052e-07 6.4182533275981095 -0.4792069290195806 QPSS(ph)PYEDK ddPTM_PC-9_Lapatinib_30min_R1 1 QPSSPYEDK 9 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QPS(0.046)S(0.954)PYEDK 80.245 0.018969999999999997 5097600.0 16005.0 33742.0 43855.0 31662.0 39867.0 39530.0 38159.0 45033.0 37692.0 32630.0 True False 15776.76576504246 33663.87247210229 40249.41118519553 33990.52910133572 37522.10144153769 37839.39404893073 40134.686306579046 47125.39758104912 33446.73004564401 38270.052023257995 0.41224834906036684 0.8796401021781634 1.051720838025896 0.8881756701213401 0.9804559821014681 0.9887468672876237 1.04872306633364 1.2313909986955187 0.8739661504854321 1.0 15.22392824171722 -4.752760577864691 2.6410582777927183 1.0115700253549458 0.26367074428388604 0.7841051949935066 0.09360412216083781 0.2375316379477506 2.0414550902191264 0.024521656650135924 0.4115051258334817 1.767011687810088e-05 4.752760577864691 -0.7478992810710597 down QPSS(ph)PYEDKDK ddPTM_PC-9_AZD4547_30min_R2 3 QPSSPYEDKDK 11 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QPS(0.039)S(0.961)PYEDKDK;QPS(0.063)S(0.937)PYEDKDK;QPS(0.008)S(0.992)PYEDKDK 185.2 0.0005533 25615700.0 58217.0 80949.0 50185.0 29364.2 47818.0 68570.0 81390.0 64693.0 72721.0 55640.0 True False 76728.79501117511 107114.1812060276 49519.51410970354 22594.73736236754 41179.29609876187 64282.3070602503 88633.55232667764 54696.18334724871 76564.88359713611 53692.06053549792 1.4290529036494457 1.994972443555416 0.9222874595577172 0.42082082782852553 0.7669531712521376 1.1972404563939347 1.6507757654053627 1.018701513812958 1.4260000982178003 1.0 15.712421151691366 -6.999551591060775 24.99945040980694 1.2966535732230433 1.0952267560639293 0.03164346581607347 0.42671663222010037 66.0805574770046 3683810.2393563758 0.16997623581848792 0.14857669530475195 1.0010330329503783e-07 6.999551591060775 -0.20142681715911404 QPSS(ph)PYEDKDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QPSSPYEDKDK 11 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QPS(0.024)S(0.976)PYEDKDK;QPS(0.037)S(0.963)PYEDKDK;QPS(0.071)S(0.929)PYEDKDK 175.6 0.0042493 20238900.0 47684.0 90847.0 44872.0 41964.0 44769.0 26091.7 50746.0 28513.300000000003 25752.899999999998 29074.9 True False 55755.95939807035 99865.68977309302 45941.91865800766 39612.893129123615 35996.83582695551 24723.40532018724 45938.971510775744 27764.856087338616 26129.4874427998 34345.94921321822 1.6233634729947244 2.907640990008195 1.33762262247586 1.1533497846633507 1.0480664139892788 0.7198346788060906 1.3375368147663798 0.8083880842825321 0.7607734839584439 1.0 15.067852336100422 -5.451571586778761 5.027255053628366 0.9904650805941683 2.26120578560953 0.693045242917645 0.33822043037928073 0.10670076726230118 5.017202029882225 0.08492150645278618 0.17936875862478233 3.5353174201648397e-06 5.451571586778761 1.2707407050153616 QPSS(ph)PYEDKDK ddPTM_PC-9_Lapatinib_30min_R1 3 QPSSPYEDKDK 11 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QPS(0.216)S(0.784)PYEDKDK;QPS(0.078)S(0.922)PYEDKDK;QPS(0.025)S(0.975)PYEDKDK 195.71 0.00060446 44503000.0 42062.0 115313.0 73781.0 80716.0 113380.0 92839.0 129510.0 133145.0 75339.0 95236.0 True False 41462.18816677389 115045.99983330956 67715.0109828961 86652.12390068252 106711.21131365644 88868.49238827926 136215.39410270329 139331.40276971975 66853.52846515905 111697.41570600691 0.3712009620339329 1.0299790653717207 0.6062361474962441 0.7757755481895406 0.9553597157030526 0.7956181602462988 1.2195035421520306 1.2474004155695675 0.5985235024695721 1.0 16.769236281643373 -6.362028081620855 1.2199881606233935 1.0166000502328325 0.6896605595443428 0.25490265663761247 0.23159210847944228 0.6580772842747123 2.021207691853574 0.09617531602521959 0.1266608957172819 4.3448212950906643e-07 6.362028081620855 -0.3269394906884897 QPSSPY(ph)EDKDK ddPTM_PC-9_AZD4547_30min_R2 1 QPSSPYEDKDK 11 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QPS(0.024)S(0.267)PY(0.709)EDKDK 113.69 0.0082244 7118400.0 32735.0 46294.0 32043.0 15571.0 23007.0 42977.0 50156.0 40268.0 45222.0 36939.0 True False 43144.0490697016 61257.63017148865 31618.088883475735 11981.346519551882 19812.8751797276 40289.6413960679 54619.78683495332 34045.50586658541 47612.34259745725 35645.77685335653 1.2103551353977295 1.7185101736875295 0.887007990134418 0.33612246883668845 0.5558267185825676 1.1302781129393196 1.532293350195568 0.9551062951060236 1.3357078117088057 1.0 15.121443542512486 -6.9867184408845775 24.814143972104347 1.2205000883729842 0.9375606416764002 0.10031306787853678 0.37733874090287134 560.1682998664618 1046566.9161082818 0.15022561745004315 0.1324138612421501 1.0310543505934793e-07 6.9867184408845775 -0.282939446696584 QPSVET(ph)LDSPTGSHVEWCK ddPTM_PC-9_AZD4547_30min_R2 2 QPSVETLDSPTGSHVEWCK 19 0 E9PPP8;Q8NEC6;F8WA39;Q13613-2;Q13613 E9PPP8 MTMR1 Myotubularin-related protein 1 1 QPS(0.008)VET(0.992)LDSPTGSHVEWCK;QPS(0.109)VET(0.737)LDS(0.144)PT(0.009)GS(0.002)HVEWCK 191.9 2.3879e-11 31836000.0 41050.0 37849.0 55840.0 89091.0 83099.0 70373.0 51500.0 94930.0 72376.0 76960.0 True False 54103.04610695737 50082.94907246459 55099.52511479215 68552.44639222884 71562.13824315119 65972.56518522675 56083.40023128034 80260.7497743854 76201.64760146759 74265.65382480086 0.7285069654754696 0.6743756567553371 0.741924729361122 0.9230706640508415 0.9635966904966932 0.8883321129961607 0.7551727796483952 1.0807250140654183 1.0260684943437501 1.0 16.18040753091917 -4.860727855186719 0.32830446054244383 1.0205768021576587 0.41169096484640605 0.5974750491130365 0.08624402146349631 5.019320124100131 0.45547707030198975 0.09748578314395952 1.222779645776364 1.3780727491927844e-05 4.860727855186719 -0.6088858373112527 QPSVET(ph)LDSPTGSHVEWCK ddPTM_PC-9_Lapatinib_30min_R1 2 QPSVETLDSPTGSHVEWCK 19 0 E9PPP8;Q8NEC6;F8WA39;Q13613-2;Q13613 E9PPP8 MTMR1 Myotubularin-related protein 1 1 QPS(0.228)VET(0.753)LDS(0.019)PTGSHVEWCK;QPS(0.015)VET(0.935)LDS(0.05)PTGSHVEWCK 148.36 0.00027006 29453000.0 65363.0 66976.0 86910.0 69181.0 88150.0 95310.0 82553.0 77182.0 102653.0 68610.0 True False 64430.91163389386 66820.92118699323 79764.5952823017 74268.80152105079 82965.19030956796 91233.81347846167 86827.19040506883 80768.15748674372 91091.13815598791 80469.1470829215 0.8006908730808265 0.830391816109793 0.9912444480131773 0.9229475421743765 1.0310186365474254 1.133773834889134 1.0790121873119336 1.0037158391092935 1.132000791087306 1.0 16.296148120758183 -5.345041889701538 0.7975514038902874 1.0708983712549847 0.7369840867056071 0.7548623881891983 0.05343508590263967 0.643189527899318 0.5335894475077608 0.02274759429380693 0.1656215268939319 4.518123628913564e-06 5.345041889701538 -0.33391428454937755 QPSVETLDS(ph)PTGSHVEWCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QPSVETLDSPTGSHVEWCK 19 0 E9PPP8;Q8NEC6;F8WA39;Q13613-2;Q13613 E9PPP8 MTMR1 Myotubularin-related protein 1 1 QPS(0.083)VET(0.115)LDS(0.787)PT(0.015)GSHVEWCK 98.00200000000001 0.00032621 9693900.0 21766.0 19517.0 25765.0 37032.0 39087.0 31199.0 39765.0 31351.0 42833.0 33261.0 True False 25450.553901904193 21454.51877664051 26379.33531430663 34957.217099363865 31428.182938377253 29562.869517299434 35998.17132633107 30528.06946913028 43459.35159292525 39290.9560060689 0.6477458552541479 0.5460421673966558 0.6713844099449264 0.8897013626740047 0.7998833862307357 0.7524090152637961 0.9161948444515011 0.7769744636504875 1.1060904597539571 1.0 15.261909650640405 -4.546535297908521 0.22196660124062406 1.0435649771928135 0.12920213473862296 0.6597408002698537 0.09425933987098896 8.373890527844024 0.3381013148873429 0.16700939430682882 2.155999764988299 2.840957272711942e-05 4.546535297908521 -0.9143628424541905 QPT(ph)PPFFGR ddPTM_PC-9_AZD4547_30min_R2 3 QPTPPFFGR 9 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 QPT(1)PPFFGR;QPT(1)PPFFGR;QPT(1)PPFFGR 106.16 0.0063281000000000006 1203130000.0 122024.0 103388.0 158131.0 197198.0 180470.0 163460.0 139127.0 179481.0 148265.0 154769.0 True False 160825.09374312678 136806.1491374665 156034.07961904 151737.04777872923 155414.85563895508 153238.82035975682 151509.03347528778 151746.33551307765 156101.98521100346 149350.5844180176 1.0768293567100693 0.9160067881258472 1.0447503786280206 1.0159789355362157 1.0406042684370367 1.026034286754824 1.0144522304059347 1.0160411230019333 1.0452050510501476 1.0 17.18834335745094 QPT(ph)PPFFGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QPTPPFFGR 9 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 QPT(1)PPFFGR 88.155 0.025274 219660000.0 43228.0 40587.0 47025.0 56098.0 56919.0 53397.0 52573.0 43084.0 44764.0 42136.0 True False 50545.646608082076 44616.20912986158 48146.25434330559 52955.0109321699 45766.1305464603 50596.767319953804 47592.90484444119 41953.090651271355 45418.58881483211 49774.92325160755 1.015484169660666 0.8963591747661939 0.9672793285874256 1.0638893537713219 0.9194615994708183 1.0165112071432418 0.9561622948942289 0.8428559585959065 0.9124793339257485 1.0 15.603131470992755 -7.537792056791036 24.792118761333988 0.9065023825091804 0.9773590651367897 0.1752834453050387 0.05772088030428151 316.8446121507583 526719.9479434718 0.02623383796741116 0.015153362952624474 2.898731188068658e-08 7.537792056791036 0.07085668262760936 QPT(ph)PPFFGR ddPTM_PC-9_Lapatinib_30min_R1 1 QPTPPFFGR 9 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 QPT(1)PPFFGR 82.494 0.03837 400820000.0 57781.0 45651.0 55055.0 49281.0 47881.0 55345.0 44837.0 39181.0 57891.0 38834.0 True False 56957.03234426232 45545.2979142891 50528.590418445754 52905.289136596744 45064.73371766793 52978.02336549637 47158.440470874106 41001.49229727277 51370.705960744366 45546.4051569476 1.2505275037183512 0.9999756897903427 1.1093870140646693 1.1615689307266137 0.9894246003033634 1.1631658565135992 1.035393250210892 0.9002135768121856 1.127876190968901 1.0 15.47504957041745 -1.522878745281189 0.20793305530820128 0.9977668686613921 1.814147941456953 0.22742661595601577 0.08821897559541049 84.7567977857342 1.0488551187228266 0.1494128103390005 22.811223978408368 0.02999999999994119 1.522878745281189 0.8163810727955609 QPT(ph)PPSEAAASK ddPTM_PC-9_AZD4547_30min_R2 1 QPTPPSEAAASK 12 0 Q86UP2-2;Q86UP2-3;Q86UP2-4;Q86UP2 Q86UP2-2 KTN1 Kinectin 1 QPT(0.769)PPS(0.225)EAAAS(0.006)K 87.863 0.02041 17136000.0 22539.0 29367.0 39838.0 36689.0 37926.0 26071.0 32771.0 39292.0 29990.0 28215.0 True False 29705.933159676322 38859.3084470149 39309.72209031323 28230.917889399447 32660.629550412876 24440.77624861868 35687.555514160944 33220.32424033662 31575.210174201533 27227.20143797761 1.091038799097482 1.4272237466467028 1.4437665281119356 1.036864473703192 1.1995588171194305 0.8976602426177995 1.3107316811628862 1.220115270238518 1.159693560358324 1.0 14.732761081393479 -5.764898282905348 24.99996266371664 1.1292474226381528 1.331331098055443 0.2930064085131908 0.1433575577568799 111.01932929063182 802423.7048698862 0.039896481473631666 0.061971081516648714 1.7183107894954077e-06 5.764898282905348 0.2020836754172901 QPT(ph)PPSEAAASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QPTPPSEAAASK 12 0 Q86UP2-2;Q86UP2-3;Q86UP2-4;Q86UP2 Q86UP2-2 KTN1 Kinectin 1 QPT(0.861)PPS(0.135)EAAAS(0.005)K;QPT(0.971)PPS(0.029)EAAASK 95.98100000000001 0.010823000000000001 28734000.0 44536.0 63366.0 52687.0 40651.0 76574.0 31683.0 46253.0 35910.0 37252.0 33863.0 True False 52075.06517390449 69656.55770869507 53943.25789656017 38373.45626232018 61569.874391058365 30021.48770526613 41871.58099727877 34967.40054979007 37796.74002613992 40002.0938406395 1.3018084848598512 1.7413227914066982 1.3485108582430594 0.9592861917476746 1.5391662905532064 0.7504979070562119 1.0467347325389251 0.87413925603728 0.9448690405235968 1.0 15.287787896910626 -6.052177903059604 0.7651307896539433 0.9237712865882739 1.5545660165688828 0.4751615934458491 0.2186465312999108 0.655957852903442 0.7766735203026158 0.11350708136153966 0.2621764523251633 8.86792674593358e-07 6.052177903059604 0.6307947299806089 QPT(ph)PPSEAAASK ddPTM_PC-9_Lapatinib_30min_R1 3 QPTPPSEAAASK 12 0 Q86UP2-2;Q86UP2-3;Q86UP2-4;Q86UP2 Q86UP2-2 KTN1 Kinectin 1 QPT(0.959)PPS(0.033)EAAAS(0.008)K;QPT(0.995)PPS(0.005)EAAASK;QPT(0.935)PPS(0.065)EAAAS(0.001)K 94.53200000000001 0.011931 50882000.0 181231.0 281152.0 135467.0 75783.0 121990.0 120682.0 132628.0 113450.0 178335.0 55010.0 True False 178646.61270630488 280501.0098179278 124329.42617774212 81356.33462467698 114814.78804156794 115520.71218348238 139494.82888621188 118721.3011695873 158249.0343491967 64518.40520378249 2.7689248074568256 4.34761226555369 1.927038118580977 1.2609786985234928 1.7795664303685663 1.790507868547095 2.1620935676512008 1.8401152476507137 2.45277349694811 1.0 15.977423157270684 -5.330433117794436 7.8414639925975935 1.7983743063482407 3.553600664978581 0.648889621258661 0.5242116482315871 0.15466689231406214 15.948904521089839 0.12995746988424256 0.2725167797703943 4.6726890596296135e-06 5.330433117794436 1.7552263586303403 QPVY(ph)DTT(ph)IRT(ph)GRALK ddPTM_PC-9_AZD4547_30min_R2 1 QPVYDTTIRTGRALK 15 2 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 3 QPVY(0.895)DT(0.479)T(0.626)IRT(1)GRALK 115.1 0.00038028 3352200.0 18254.0 18621.0 18666.0 27701.0 23039.0 22988.0 13955.0 23302.0 16953.0 21478.0 True False 24058.392293213175 24639.874096498268 18418.47664385226 21314.962426183713 19840.432532087798 21550.556725988514 15196.967965582866 19701.2113266905 17849.100969764553 20726.061757394404 1.1607797262608224 1.188835312029674 0.8886626344863191 1.028413534403332 0.9572697777477845 1.0397805901692807 0.7332298891834127 0.9505525727608011 0.8611911504797364 1.0 14.33915838973327 -4.54669552891125 0.6057583092308118 0.904916278256998 1.4751619654741561 0.46932051969561106 0.0942360626107749 3.935046198121884 0.8939504288675614 0.045494123260616616 1.6675261580295127 2.8399093075913483e-05 4.54669552891125 0.5702456872171581 QPVYDT(ph)T(ph)IRT(ph)GRALK ddPTM_PC-9_AZD4547_30min_R2 1 QPVYDTTIRTGRALK 15 2 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 3 QPVY(0.242)DT(0.865)T(0.893)IRT(1)GRALK 94.007 0.018963999999999998 0.0 15090.0 16632.0 21175.0 28229.0 18345.0 21237.0 15961.0 23637.0 16966.0 19360.0 True False 19888.30610850152 22007.96874351319 20894.20566450079 21721.2401837024 15798.113407749928 19909.04703279182 17381.49807944594 19984.444774224678 17862.788123224513 18682.212292725373 1.064558404373008 1.1780172711174481 1.1184010403648363 1.1626695941229823 0.8456232677487303 1.0656686007440437 0.9303768636765831 1.0697044044407085 0.9561388042988926 1.0 14.189377684423722 -6.229646939752264 24.99745107682793 0.983414255893797 1.1333826826826023 0.5551987551324802 0.06696367970118805 486.5560298389274 382564.53364250687 0.01839913418334274 0.023751052266695202 5.893225511822437e-07 6.229646939752264 0.1499684267888053 QPYPSRPPFDNQHS(ph)QDLDSR ddPTM_PC-9_AZD4547_30min_R2 1 QPYPSRPPFDNQHSQDLDSR 20 1 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 QPYPSRPPFDNQHS(1)QDLDSR 106.74 5.8648000000000005e-05 11679000.0 1854.8 4054.2 6345.1 6430.1 7367.8 8431.1 8711.1 12042.0 10344.0 7270.1 True False 2444.587817763327 5364.640865797932 6260.9598281853105 4947.7397890546845 6344.908147485417 7903.9019841866075 9486.371024363225 10181.185597631407 10890.762722305466 7015.576011846216 0.34845147620601585 0.7646757524598718 0.8924370312021862 0.7052506851468978 0.9044030221854433 1.1266219581742682 1.3521870489814272 1.4512258979789932 1.5523690006231516 1.0 12.77634584543074 -6.752419562263802 1.228755369259665 1.392741192395185 0.6712472758553059 0.7214929487979079 0.18548390447709082 0.2340343789757 0.7448955779336437 0.09165554372694555 0.0833355238746643 1.7683997210850706e-07 6.752419562263802 -0.721493916539879 QPYPSRPPFDNQHS(ph)QDLDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QPYPSRPPFDNQHSQDLDSR 20 1 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 QPYPSRPPFDNQHS(0.955)QDLDS(0.045)R 67.55199999999999 0.019435 0.0 1482.5 3627.4 2500.3 3774.4 3523.6 2410.2 2826.8 2870.0 2382.8 3069.8 True False 1733.4579692903126 3987.5042993485554 2559.9166344405544 3562.932604769904 2833.175874374243 2283.8048690853902 2559.025039740293 2794.665541016358 2417.6439421852847 3626.330439476569 0.47801986008217245 1.09959761414465 0.7059248121939095 0.9825173585902404 0.7812790151531774 0.6297839943717425 0.7056789452727499 0.7706593725142558 0.6666915722479642 1.0 11.824294677387137 -4.701730510646088 24.13234654778254 0.8000700135135836 0.4780043163702753 0.30514372349692453 0.15124617218995395 32886.04290707045 13288826.51049979 0.03682988592877475 113.53494406896544 1.987327715733212e-05 4.701730510646088 -0.32206569714330835 QPYPSRPPFDNQHS(ph)QDLDSR ddPTM_PC-9_Lapatinib_30min_R1 2 QPYPSRPPFDNQHSQDLDSR 20 1 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 QPYPSRPPFDNQHS(1)QDLDSR;QPYPSRPPFDNQHS(0.993)QDLDS(0.007)R 156.0 8.7947e-06 23641000.0 3298.71 13499.5 9876.1 14107.2 20341.7 11717.7 24249.7 21973.7 17325.2 25308.5 True False 3251.669790490674 13468.242737156805 9064.125180848465 15144.690548239641 19145.24119932094 11216.56128629283 25505.23081130663 22994.67832093573 15373.85353355597 29683.04050354351 0.10954638525330636 0.45373528144965436 0.305363770930623 0.5102135863215123 0.6449892219442753 0.3778777745141646 0.859252636476437 0.7746739528988166 0.5179339202707575 1.0 14.85735125771826 -6.249841004615208 0.243236990664364 0.9807579578593665 6.738234909717659e-16 0.658813772952717 0.1492289730975515 3.1813696041627564 0.31591796762116586 0.2710436191249317 0.9566357647085357 5.6254723626582e-07 6.249841004615208 -0.9807579578593658 QQAAYYAQT(ph)SPQGMPQHPPAPQGQ ddPTM_PC-9_AZD4547_30min_R2 1 QQAAYYAQTSPQGMPQHPPAPQGQ 24 0 Q96AE4 Q96AE4 FUBP1 Far upstream element-binding protein 1 1 QQAAY(0.003)Y(0.009)AQT(0.552)S(0.436)PQGMPQHPPAPQGQ 72.058 0.00054193 14393000.0 30292.0 24730.0 42119.0 51498.0 45972.0 41242.0 36161.0 49409.0 32390.0 38762.0 True False 39924.225887258304 32723.488878492142 41560.47453993428 39625.9317361687 39589.5813344824 38663.131220341864 39379.258946860726 41773.97435586865 34102.06927450445 37404.954178234555 1.0673512844587223 0.8748437098081918 1.1110954538775446 1.0593765613867936 1.05840475424293 1.0336366417162843 1.0527819058197108 1.1168032490246005 0.9116992661455522 1.0 15.190941743112244 -5.277592320701791 24.95311531282369 1.048299875031865 0.9710974705385012 0.1418927912050384 0.06972667644081591 1165.2472921695942 1800077.2882139857 0.016992010645444016 0.03555555322059057 5.277250130413711e-06 5.277592320701791 -0.07720240449336391 QQAAYYAQT(ph)SPQGMPQHPPAPQGQ ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QQAAYYAQTSPQGMPQHPPAPQGQ 24 0 Q96AE4 Q96AE4 FUBP1 Far upstream element-binding protein 1 1 QQAAYYAQT(0.661)S(0.338)PQGMPQHPPAPQGQ 87.792 1.7443e-05 18861000.0 16510.0 16050.0 18514.0 21009.0 24533.0 21153.0 23890.0 17789.0 17101.0 16359.0 True False 19304.816912636128 17643.33792924528 18955.443974736005 19831.933842097 19725.93476161407 20043.699442271707 21626.966251378086 17322.057599003503 17351.069773086507 19324.757202227243 0.9989681479884872 0.9129914412177881 0.9808891142265593 1.026244916536975 1.0207597723059925 1.0372031706541494 1.119132624801387 0.8963661182251271 0.8978674138833029 1.0 14.238162667679227 -7.822377515398527 24.99999485669391 0.9228372696593192 1.0102584566460802 0.3122782233971695 0.05538485282777065 90.0825384346186 36954.95328928477 0.032172948016495284 0.015455388834935191 1.5052979999688215e-08 7.822377515398527 0.08742118698676093 QQAAYYAQT(ph)SPQGMPQHPPAPQGQ ddPTM_PC-9_Lapatinib_30min_R1 2 QQAAYYAQTSPQGMPQHPPAPQGQ 24 0 Q96AE4 Q96AE4 FUBP1 Far upstream element-binding protein 1 1 QQAAYY(0.003)AQT(0.603)S(0.393)PQGMPQHPPAPQGQ;QQAAYY(0.001)AQT(0.558)S(0.441)PQGMPQHPPAPQGQ 77.469 0.00021482 15420000.0 42481.9 32706.9 36056.2 28698.4 34429.0 30655.3 33176.9 32755.6 37799.0 28149.1 True False 41876.100315773656 32631.16918255596 33091.79841695693 30808.97607105595 32403.953910018332 29344.24427999459 34894.63754618154 34277.54475619683 33541.67857888406 33014.63442868194 1.268410238078941 0.9883849919055038 1.0023372661733294 0.9331914953536548 0.9815027326750264 0.8888253584447192 1.056944538385266 1.0382530459406731 1.015963955358665 1.0 15.010818050614489 -4.761436433543263 12.019068713087794 0.9880157176049637 1.268790870631545 0.7667677382133531 0.046142872748463924 0.029754072438069486 232.30031593909035 0.012111214056651545 0.06779193660401757 1.7320625292982716e-05 4.761436433543263 0.2807751530265813 QQAAYYAQTS(ph)PQGMPQHPPAPQGQ ddPTM_PC-9_AZD4547_30min_R2 3 QQAAYYAQTSPQGMPQHPPAPQGQ 24 0 Q96AE4 Q96AE4 FUBP1 Far upstream element-binding protein 1 1 QQAAYYAQT(0.051)S(0.948)PQGMPQHPPAPQGQ;QQAAYYAQT(0.073)S(0.927)PQGMPQHPPAPQGQ;QQAAYYAQT(0.345)S(0.655)PQGMPQHPPAPQGQ 93.06200000000001 5.7019e-06 52126000.0 75159.0 72373.0 99745.0 128564.0 106191.0 100330.0 91661.0 122411.0 84165.0 101801.0 True False 99057.9985956834 95766.15691884806 98422.31612777471 98925.55609399966 91448.21264008587 94056.34923953464 99818.65142911438 103495.19267494249 88613.79007374709 98236.97797581289 1.0083575516754257 0.9748483604862808 1.001886643459324 1.0070093577019064 0.9308939925106563 0.9574434309521658 1.0161005915073134 1.0535258189683343 0.9020410837105032 1.0 16.583978559899563 -8.273341069583315 24.981924948852175 0.9510205644167765 0.9912793223695465 0.16074317710456376 0.03873183023411464 1664.1566207249452 3493066.21568035 0.036564880418449734 0.009752658410106346 5.329162097609549e-09 8.273341069583315 0.04025875795277001 QQAAYYAQTS(ph)PQGMPQHPPAPQGQ ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QQAAYYAQTSPQGMPQHPPAPQGQ 24 0 Q96AE4 Q96AE4 FUBP1 Far upstream element-binding protein 1 1 QQAAYYAQT(0.24)S(0.76)PQGMPQHPPAPQGQ;QQAAYYAQT(0.225)S(0.775)PQGMPQHPPAPQGQ;QQAAYY(0.001)AQT(0.255)S(0.744)PQGMPQHPPAPQGQ 104.01 1.2303e-06 50326000.0 90001.0 89850.0 100887.0 105476.0 130322.0 106631.0 105408.0 92494.0 92675.0 82298.0 True False 105236.39169922267 98769.71420203682 103292.52869607793 99566.52167780587 104786.33962430495 101039.08264685262 95422.99115216652 90066.13050549365 94030.19655112509 97217.97592939025 1.0824787359866064 1.0159614336526983 1.0624838432256567 1.0241575256629636 1.0778494267398824 1.0393045286217197 0.9815364930192804 0.926434948315618 0.9672099799672804 1.0 16.56893547719138 -7.307510353914475 3.387292435793208 0.9594609643185255 1.0501912292682163 0.7060014143261204 0.025908033010287577 0.12423126867308318 2.9127061149049718 0.01087126515808099 0.007240373448990515 4.925945993754692e-08 7.307510353914475 0.09073026494969083 QQAAYYAQTS(ph)PQGMPQHPPAPQGQ ddPTM_PC-9_Lapatinib_30min_R1 3 QQAAYYAQTSPQGMPQHPPAPQGQ 24 0 Q96AE4 Q96AE4 FUBP1 Far upstream element-binding protein 1 1 QQAAYY(0.001)AQT(0.25)S(0.749)PQGMPQHPPAPQGQ;QQAAYYAQT(0.294)S(0.705)PQGMPQHPPAPQGQ;QQAAYYAQT(0.258)S(0.742)PQGMPQHPPAPQGQ 101.05 2.2144e-06 37533000.0 117045.0 96386.0 102383.0 87957.0 94573.0 99144.0 80756.0 83823.0 97968.0 72731.0 True False 115375.9168365755 96162.82413893819 93965.46494980899 94425.65119595062 89010.40207767196 94903.84223595206 84937.15053785723 87717.722590906 86933.81219122505 85302.4564420343 1.352550930523051 1.1273160017881063 1.1015563779650528 1.1069511375691252 1.0434682163948856 1.112556967224528 0.9957175218696627 1.0283141453319455 1.0191243701205641 1.0 16.380299666763754 -1.522878745280338 0.6514010188011867 1.034985514959599 27.893934033908227 0.8668635661074157 0.03634575841915274 76.07905987023793 0.4884137054254215 0.015261580131733666 2947.649995077714 0.029999999999999964 1.522878745280338 26.85894851894863 QQAEPWT(ph)PTANLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QQAEPWTPTANLK 13 0 F8VSE7;Q96AV8-2;Q96AV8-3;Q96AV8;F8VXV5 F8VSE7 E2F7 Transcription factor E2F7 1 QQAEPWT(0.943)PT(0.057)ANLK 121.18 0.00072568 0.0 8882.3 10422.0 12301.0 11666.0 12251.0 11892.0 10413.0 10645.0 9802.3 7412.8 True False 10385.897956578316 11456.627283401522 12594.302491802284 11012.391841682309 9850.504494539346 11268.362585330457 9426.605256408533 10365.58002930981 9945.640093370317 8756.681960307493 1.1860540332120972 1.3083297229855337 1.4382505324379775 1.2575986990962507 1.1249128995651503 1.28683017567704 1.076504239749449 1.1837337562669479 1.1357772428474808 1.0 13.096168598984708 -7.640374170836756 0.3761956421247307 1.00442464570005 1.325636555492339 0.5158497621298812 0.0837368685493717 1.0165464408626275 0.3990427631012269 0.108946741831547 0.10773237448274056 2.2888947823907453e-08 7.640374170836756 0.321211909792289 QQAGAQGPGS(ph)ADLEDGEMGKR ddPTM_PC-9_Lapatinib_30min_R1 1 QQAGAQGPGSADLEDGEMGKR 21 1 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 QQAGAQGPGS(1)ADLEDGEMGKR 87.80799999999999 0.00020228 5542400.0 13316.0 10963.0 9721.0 9600.5 9021.0 10731.0 12242.0 10284.0 14590.0 8051.0 True False 13126.11139814467 10937.615847064708 8921.776904145147 10306.552796329159 8490.402515968388 10272.060145182782 12875.830859433969 10761.832183587789 12946.720560488853 9442.604622716828 1.3900943566530506 1.1583261487779772 0.9448427907996185 1.0914946890325008 0.8991589561573242 1.087841814372961 1.3635889009328586 1.1397101343941893 1.3710963317623077 1.0 13.204969148272045 -7.123305876152984 11.36723172721717 1.230154010067796 1.0817139948914745 0.12162559288834762 0.1587279222846052 0.9596839779997894 84.54408556070359 0.060800165680199296 0.04709666933094966 7.528251577937933e-08 7.123305876152984 -0.14844001517632144 QQDLHLES(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 1 QQDLHLESPQR 11 0 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 QQDLHLES(1)PQR 98.25299999999999 0.0050528 9222500.0 23513.0 28783.0 28087.0 22298.0 24598.0 33899.0 31345.0 34232.0 35722.0 28866.0 True False 30989.64489921778 38086.54186775735 27714.548028280205 17157.540600665827 21182.99229238662 31779.290171145134 34134.644276688996 28942.230973104 37610.19199209161 27855.410126126582 1.112517990541144 1.3672942417758416 0.9949430973297981 0.615950026331623 0.7604624091503983 1.1408659943347308 1.2254224268151377 1.0390165085366325 1.3501934389691743 1.0 14.765669937065143 -6.962636086285749 24.940416029331804 1.1606575552570566 0.9716508185626274 0.16005918735355917 0.20706741431515613 343.0441723581894 228980.97438201975 0.08178370741570644 0.07212632347131077 1.0898429363148373e-07 6.962636086285749 -0.18900673669442924 QQDLHLES(ph)PQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QQDLHLESPQR 11 0 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 QQDLHLES(1)PQR 92.039 0.0078646 7200500.0 15238.0 25397.0 25950.0 18181.0 27346.0 14236.0 24201.0 14888.0 12522.0 15836.0 True False 17817.49243578132 27918.246317074292 26568.746415923026 17162.377513597283 21987.74760490353 13489.43909895429 21908.50607993306 14497.205775139913 12705.110560703431 18706.941442292984 0.9524535312597504 1.4924003693065626 1.4202613771942394 0.9174336471057891 1.1753790790830851 0.7210927099208814 1.1711431367610914 0.7749639790053746 0.6791655706998415 1.0 14.191286078868895 -6.162659856886222 1.3911855285636485 0.8811313574229372 1.2936120351404479 0.35431939197870166 0.2141571538790322 0.441563302145526 1.7217374927964901 0.0789035262175219 0.12091309690900821 6.876067686155368e-07 6.162659856886222 0.4124806777175106 QQDLHLES(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 1 QQDLHLESPQR 11 0 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 QQDLHLES(1)PQR 98.25299999999999 0.0050528 8058400.0 45110.0 50049.0 47247.0 49986.0 61824.0 48423.0 43851.0 49248.0 45491.0 43140.0 True False 44466.72312783914 49933.1146155014 43362.534038694146 53662.13718840781 58187.63387066064 46352.06116952623 46121.39021540916 51536.24186866308 40367.32453853316 50596.6915195633 0.8788464579871987 0.9868849744097334 0.8570231123101784 1.0605858916221678 1.1500284331469044 0.9161085394606112 0.9115495268613808 1.0185694028775873 0.7978253780274361 1.0 15.62675543078581 -10.51869326087515 13.108324180158597 1.0000001687279505 0.9597945597262699 0.015791680889570614 0.0990559563576631 0.0 0.0 0.09696268611850328 0.023516905682952963 3.0290520708396445e-11 10.51869326087515 -0.040205609001680576 QQDLHLES(ph)PQRQPEYS(ph)PESPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QQDLHLESPQRQPEYSPESPR 21 1 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 2 QQDLHLES(1)PQRQPEY(0.218)S(0.752)PES(0.03)PR 53.705 0.0097 5191200.0 17364.0 12603.0 22785.0 21790.0 24681.0 15848.0 17990.0 19705.0 22669.0 16720.0 True False 20303.382245367287 13854.142549674661 23328.280812593694 20569.176944133156 19844.935224040943 15016.902981190471 16285.856963679013 19187.76462917331 23000.49123946541 19751.203644552825 1.027956706373525 0.7014328239937665 1.1811067939156907 1.0414138456724342 1.0047456135420876 0.7603031820965491 0.8245501011868955 0.9714731807985331 1.164510864926893 1.0 14.269652953807043 -8.055727289723984 8.269760675999628 1.0785798492991572 0.9325193314338358 0.1473401645895519 0.14009317547328773 0.7131442875994702 97.64128343235492 0.09725574937436411 0.036865415718477755 8.795746623523687e-09 8.055727289723984 -0.14606051786532137 QQDLHLES(ph)PQRQPEYS(ph)PESPR ddPTM_PC-9_Lapatinib_30min_R1 2 QQDLHLESPQRQPEYSPESPR 21 1 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 2 QQDLHLES(0.999)PQRQPEY(0.366)S(0.446)PES(0.188)PR;QQDLHLES(0.975)PQRQPEY(0.034)S(0.889)PES(0.102)PR 73.058 0.006144 93696000.0 38369.0 38762.0 47559.0 48250.0 42767.0 40731.0 41149.0 35904.0 47540.0 35573.0 True False 37821.85102398714 38672.24897053017 43648.88260304899 51798.46595728155 40251.529143157044 38989.03007859845 43279.49387639669 37572.230913996114 42185.54458160659 41721.745651957 0.9065260916812351 0.926908698718751 1.0461902281646644 1.2415220204203488 0.9647613855598348 0.9345014085423253 1.037336602294507 0.9005431179084367 1.0111164794857483 1.0 15.348511901518693 -7.709220807060642 24.999792463597373 0.9668694480013649 1.0110431775232493 0.03160753867198196 0.09407704366389909 391.2712685593483 187321.30902452805 0.04793009009378006 0.027672411665717114 1.95334606929218e-08 7.709220807060642 0.044173729521884475 QQDLHLES(ph)PQRQPEYSPESPR ddPTM_PC-9_AZD4547_30min_R2 2 QQDLHLESPQRQPEYSPESPR 21 1 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 QQDLHLES(0.998)PQRQPEY(0.001)SPESPR;QQDLHLES(0.998)PQRQPEY(0.001)S(0.001)PESPR 72.968 0.00081626 32814000.0 137114.0 108595.0 185437.0 218590.0 195732.0 184515.0 175152.0 216063.0 183223.0 191456.0 True False 180713.39985162867 143696.2100590317 182977.98421761664 168197.4526818344 168557.99038025123 172977.2478813191 190740.18868561543 182675.4279838096 192907.7937228318 184753.18371467132 0.9781341583304913 0.7777739315223542 0.99039150794935 0.9103900095253286 0.9123414654687002 0.9362612562523486 1.0324054224699604 0.9887538840246967 1.0441378591924795 1.0 17.495239699916723 -7.13218458784039 3.694198460258339 1.0153919178292317 0.9110955794851898 0.4348583058996106 0.05545560017811121 0.2280336127630047 5.558877500897444 0.021414555707597222 0.01627354606957615 7.375906659190809e-08 7.13218458784039 -0.10429633834404184 QQDLHLES(ph)PQRQPEYSPESPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QQDLHLESPQRQPEYSPESPR 21 1 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 QQDLHLES(0.999)PQRQPEYS(0.001)PESPR 76.76100000000001 0.00054496 15406000.0 80254.0 76686.0 102370.0 98162.0 135910.0 92075.0 95425.0 123790.0 113620.0 87786.0 True False 93839.41711124762 84298.879279882 104810.88904038684 92662.30138549788 109279.41113809842 87246.42491122626 86385.65318282775 120540.64366634696 115281.47755207837 103700.90688640636 0.9049044982223639 0.812903973657846 1.0107036880130311 0.8935534333079639 1.0537941703615257 0.8413275016658796 0.8330269789969563 1.1623875555725545 1.1116728003001684 1.0 16.662068985316978 -7.764598626308419 24.999983118242163 1.1027726556123916 0.9101125158627003 0.5198366698188004 0.08085963870596924 63.88748414196936 505540.93862847844 0.042008320507386114 0.0215140386714787 1.719496806964323e-08 7.764598626308419 -0.19266013974969132 QQDLHLES(ph)PQRQPEYSPESPR ddPTM_PC-9_Lapatinib_30min_R1 2 QQDLHLESPQRQPEYSPESPR 21 1 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 QQDLHLES(0.9)PQRQPEY(0.045)S(0.053)PES(0.002)PR;QQDLHLES(0.992)PQRQPEY(0.004)S(0.004)PESPR 53.037 0.011015 29775000.0 76231.0 60993.0 101140.0 83324.0 93218.0 86082.0 62601.0 79599.0 93507.0 82513.0 True False 75143.93196094666 60851.774455898725 92824.65961169003 89451.92492071561 87735.10051363928 82400.47352694286 65842.17347095453 83297.46013043614 82975.25698763758 96775.26210833876 0.776478723217757 0.6287947263607087 0.959177558287302 0.9243263513001415 0.9065860283118724 0.8514621581153302 0.6803616134590779 0.8607309173411033 0.8574015216279937 1.0 16.562350689500654 -14.522878745280336 0.3053494295566787 2.4754050030615633 0.8196204354906631 0.21716127681902642 0.0993691181144565 500.26811552545763 4.576123238107673 473.7853044511206 0.10428833147684238 3.0000000000000132e-15 14.522878745280336 -1.6557845675709002 QQDLHLESPQRQPEYS(ph)PESPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QQDLHLESPQRQPEYSPESPR 21 1 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 QQDLHLES(0.01)PQRQPEY(0.127)S(0.566)PES(0.297)PR 51.942 0.013899000000000002 13675000.0 17324.0 6814.9 15950.0 32931.0 36939.0 41336.0 23310.0 44022.0 35748.0 26973.0 True False 20256.61103540329 7491.43823389493 16330.30849071185 31085.9828337425 29701.068118830208 39168.26739213086 21101.908050214442 42866.46914516455 36270.74687142835 31862.991381849497 0.6357410323671716 0.2351140903287056 0.51251648958529 0.9756140740586706 0.9321493943518808 1.2292715057018393 0.6622701490053748 1.345337248202725 1.1383346414891133 1.0 14.959594096794685 -5.759602027142011 3.357363751278694 1.0510393092335435 0.4187075412754878 0.6551803342646825 0.193667612626573 0.13523147333267496 3.181509820025889 0.05432018620696351 0.09340668927063872 1.7393940208493266e-06 5.759602027142011 -0.6323317679580557 QQDLHLESPQRQPEYSPES(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 QQDLHLESPQRQPEYSPESPR 21 1 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 QQDLHLES(0.004)PQRQPEY(0.015)S(0.223)PES(0.757)PR;QQDLHLES(0.002)PQRQPEY(0.047)S(0.225)PES(0.726)PR 59.56100000000001 0.0047531000000000006 28889000.0 393180.0 90591.0 174263.0 124163.0 105085.0 129302.0 57660.0 50667.0 161137.0 71858.0 True False 387573.1810996182 90381.24210539447 159935.76881463322 133294.36121562571 98904.10690505907 123772.05487768381 60645.35266745323 53021.17378897728 142988.05421216556 84278.55955523372 4.5987162469906 1.0724108549359013 1.89770410954658 1.581592778982755 1.1735381742047952 1.4686066720986992 0.7195822162540406 0.6291181774912603 1.696612459524244 1.0 16.36287803613134 -4.759530703072235 24.999986671946132 1.2558635335385306 4.59872046134797 0.8674002969208245 0.39292304709901693 17.586012020966333 230281.2138121842 0.10287537750551709 0.6496000393459692 1.739679704535085e-05 4.759530703072235 3.3428569278094393 QQDPS(ph)PGSNLGGGDDLK ddPTM_PC-9_AZD4547_30min_R2 2 QQDPSPGSNLGGGDDLK 17 0 Q13951-2;J3KTD8 Q13951-2 CBFB Core-binding factor subunit beta 1 QQDPS(0.972)PGS(0.028)NLGGGDDLK;QQDPS(0.967)PGS(0.033)NLGGGDDLK 240.82 6.7865e-38 24569000.0 92151.0 86487.0 103747.0 107522.0 90445.0 110120.0 100771.0 105459.0 101574.0 103204.0 True False 121453.10114012763 114442.23140453482 102371.24699291444 82734.46409834028 77888.27294434138 103234.17899190255 109739.42378070559 89162.73475673575 106942.99427256912 99590.85937285263 1.2195205654911179 1.149123846557855 1.027918100492059 0.8307435503553128 0.7820825468805309 1.036582871580713 1.1019025688879571 0.8952903440959816 1.0738233904799561 1.0 16.603725714788517 -5.280230364877662 2.8969979807900454 0.956409610906526 1.2003092585072417 0.4516553863063183 0.09770997788534064 0.2509292702882718 4.171643724626029 0.028467932548757586 0.08314970388854247 5.245291579617108e-06 5.280230364877662 0.2438996476007157 QQDPS(ph)PGSNLGGGDDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QQDPSPGSNLGGGDDLK 17 0 Q13951-2;J3KTD8 Q13951-2 CBFB Core-binding factor subunit beta 1 QQDPS(1)PGSNLGGGDDLK;QQDPS(0.96)PGS(0.04)NLGGGDDLK 216.34 2.2701e-22 18845800.0 85799.0 96358.0 84787.0 99242.0 113934.0 97459.0 92881.0 80461.0 84335.0 82820.0 True False 100323.0760925058 105923.78543216316 86808.64363648815 93681.79248690497 91609.45058206246 92348.07847323595 84082.63927979264 78348.98400547658 85568.23982885506 97834.61039724074 1.025435433178106 1.082682140830098 0.887299936944773 0.9575526708444593 0.9363705769369134 0.9439203375806612 0.8594365423278063 0.8008309501857666 0.8746213582434664 1.0 16.57805730909604 -5.122141267480595 0.6255577705067512 0.8810059884321945 1.1286840162281042 0.4134606761194013 0.06146116789850916 2.2288214828352144 0.8812588980642652 0.032175412384632875 0.3731170672711385 7.548466509102178e-06 5.122141267480595 0.24767802779590975 QQDPS(ph)PGSNLGGGDDLK ddPTM_PC-9_Lapatinib_30min_R1 2 QQDPSPGSNLGGGDDLK 17 0 Q13951-2;J3KTD8 Q13951-2 CBFB Core-binding factor subunit beta 1 QQDPS(0.541)PGS(0.459)NLGGGDDLK;QQDPS(0.807)PGS(0.193)NLGGGDDLK 225.29 5.959399999999999e-29 17083000.0 55553.3 71627.0 69870.9 65582.2 71901.1 68436.5 67980.0 63003.0 63556.8 55440.9 True False 54761.09975477248 71461.1520822497 64126.384311473616 70405.33376380595 67672.01866100158 65509.63042827343 71499.67177130534 65930.3493837593 56398.36390122534 65023.78569464429 0.842170279225728 1.0990001784552452 0.9861988751718498 1.0827627615290463 1.0407271421998336 1.0074718001795635 1.0995925722791995 1.0139420318185146 0.8673497443854705 1.0 15.98867993194651 -8.092365435758417 8.284516650315968 0.9347413148710993 1.0286510273626712 0.17086366514530626 0.07673743359359679 0.4991526760365458 40.54612027138082 0.048516116174328876 0.018247941598083142 8.084153742710726e-09 8.092365435758417 0.09390971249157187 QQDPSPGS(ph)NLGGGDDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QQDPSPGSNLGGGDDLK 17 0 Q13951-2;J3KTD8 Q13951-2 CBFB Core-binding factor subunit beta 1 QQDPS(0.082)PGS(0.918)NLGGGDDLK 96.756 0.0015209000000000002 4306100.0 18454.0 23315.0 19699.0 25210.0 24103.0 23436.0 30618.0 22357.0 16938.0 19276.0 True False 21577.89771688596 25629.55911653295 20168.69886887351 23797.565431922743 19380.190174833235 22206.97490327992 27717.641384876282 21770.15243919956 17185.686206452203 22770.586211267953 0.9476215287864748 1.1255555249539533 0.8857347229336192 1.0451011322732917 0.8511063349455188 0.9752482741217645 1.217256381882707 0.9560646457326016 0.7547318302217411 1.0 14.474883812578787 -8.009137373558609 24.809675811849043 0.8700433266260358 1.007104946670912 0.16510280110351294 0.11551743424886786 624.5492487621821 1695758.5124325154 0.06729112236686662 0.029551745042989925 9.791802077076942e-09 8.009137373558609 0.13706162004487632 QQDPSPGS(ph)NLGGGDDLK ddPTM_PC-9_Lapatinib_30min_R1 1 QQDPSPGSNLGGGDDLK 17 0 Q13951-2;J3KTD8 Q13951-2 CBFB Core-binding factor subunit beta 1 QQDPS(0.274)PGS(0.726)NLGGGDDLK 229.22 2.8231e-29 15412000.0 42374.0 58686.0 51905.0 50830.0 58470.0 51429.0 50245.0 49367.0 55091.0 46661.0 True False 41769.7389895601 58550.11617265707 47637.57125909417 54568.2077639093 55030.909556442915 49229.5015568545 52846.44024932688 51660.77104309395 48886.07144605151 54726.29167812571 0.7632481154621265 1.0698717997744356 0.8704695640493229 0.9971113717124086 1.0055662071917613 0.899558512869815 0.9656499395234884 0.9439844992044827 0.8932830993478669 1.0 15.739946480589012 -4.738151813941411 24.927876597839422 0.9568382748681626 0.7632472735013649 0.5092593535925661 0.05801595439547456 1600.0797760938567 1712693.8907670386 0.013525460812149398 0.7851793588985079 1.827461288850757e-05 4.738151813941411 -0.19359100136679774 QQEELLAEENQR ddPTM_PC-9_Lapatinib_30min_R1 2 QQEELLAEENQR 12 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 124.6 0.0014636 4552800.0 71072.0 22815.3 25146.0 17578.3 21485.0 21692.0 17745.0 17708.4 22301.0 21225.5 False True 70058.5002469913 22762.472574617863 23078.592946367047 18871.066821489792 20221.29454113522 20764.283726521753 18663.749273048164 18531.196911692536 19789.22654005907 24894.29939379904 2.814238679255311 0.9143648597834331 0.9270633642381488 0.758047716988188 0.8122861471719977 0.8340979353567974 0.7497198044343094 0.7443951974124847 0.7949300451085761 1.0 14.603527793414361 -4.760249193412797 5.333310969724198 0.8191335021969303 2.922666259745104 0.9834188901791787 0.07708068534587519 0.017874911650073287 1.5114003148726314 0.019512771550067604 0.13983358449655853 1.7368039837010745e-05 4.760249193412797 2.103532757548174 up QQELTHQEHR ddPTM_PC-9_AZD4547_30min_R2 3 QQELTHQEHR 10 0 P18206;P18206-2;P18206-3 P18206 VCL Vinculin 0 ;; 104.43 0.0010958 20090700.0 51810.0 52456.0 67597.0 86092.0 89874.0 84573.0 58773.0 70453.0 60739.0 69043.0 False True 68284.50228505388 69411.37616701104 66700.61961290477 66244.81950814076 77396.54643816395 79284.63694044822 64003.68314161241 59566.10769888106 63949.5395388739 66625.8255850536 1.0248954018270715 1.0418088715223717 1.0011225981396012 0.9942814055425633 1.1616598482424898 1.189998566535353 0.9606437530729913 0.8940393184747828 0.9598311011881844 1.0 16.02379388449568 -7.492649620426395 24.636034633746284 0.9416294108672183 1.0662839806134816 0.4290036395991099 0.06492112213941964 564.0508640470274 459689.70531566255 0.029938368941833302 0.020150371692973904 3.216254297933186e-08 7.492649620426395 0.12465456974626332 QQELTHQEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QQELTHQEHR 10 0 P18206;P18206-2;P18206-3 P18206 VCL Vinculin 0 ;; 101.66 0.0014784000000000002 15177800.0 43353.0 44249.0 42183.0 47616.0 62825.0 53144.0 57844.0 48643.0 46671.0 39219.0 False True 50691.80663921952 48641.7482885467 43188.80269991837 44948.22989315485 50514.89224303606 50357.03508533486 52364.597565705866 47366.17279151877 47353.475082142584 46329.09424256682 1.0941678758883284 1.0499179637286118 0.9322177220602087 0.9701944453698549 1.090349230195469 1.0869419294424107 1.1302745806239758 1.0223850382984414 1.0221109619413749 1.0 15.49963085677212 -4.814602258529994 4.853088316779107 1.0352713181540796 1.095570521891598 0.09830903322888274 0.05588834206830974 0.485419933329444 22.16112869934469 0.01563704175618995 0.08274100371876306 1.5324903252896446e-05 4.814602258529994 0.060299203737518514 QQELTHQEHR ddPTM_PC-9_Lapatinib_30min_R1 4 QQELTHQEHR 10 0 P18206;P18206-2;P18206-3 P18206 VCL Vinculin 0 ;;; 149.38 0.00010589 14453900.0 55492.1 45228.8 61320.9 46130.4 54433.2 54435.0 46199.299999999996 47718.4 58795.9 42627.1 False True 54700.772477995175 45124.07549244922 56279.332307519224 49522.98350250328 51231.54619578877 52106.941944182734 48591.27369908901 49935.57106858378 52173.68659372496 49995.13743795958 1.0941218542678266 0.9025692858319472 1.125696121494973 0.990556002850433 1.0247305802361977 1.042240198036134 0.9719199944072028 0.9988085567431488 1.0435752208596047 1.0 15.609500163731171 QQFILT(ph)SPDGAGTGK ddPTM_PC-9_AZD4547_30min_R2 2 QQFILTSPDGAGTGK 15 0 C9JKS0;P49116;P49116-2;C9JMI6 C9JKS0 NR2C2 Nuclear receptor subfamily 2 group C member 2 1 QQFILT(0.619)S(0.38)PDGAGTGK;QQFILT(0.5)S(0.5)PDGAGTGK 112.5 0.00076267 9558300.0 63524.0 57709.0 80373.0 103896.0 90053.0 80688.0 78393.0 91728.0 74079.0 95211.0 True False 83723.3106187177 76362.30568899728 79307.20150521476 79944.38237719872 77550.69537792902 75642.56660460054 85369.82513263624 77553.54529974535 77994.66470472416 91877.69186997303 0.9112474303033694 0.8311299961373279 0.8631823448226338 0.8701174436373245 0.8440644709238034 0.8232963308618076 0.9291681516494031 0.8440954895721644 0.848896648547763 1.0 16.487426993670923 -11.042452020905674 3.2094178324178695 1.0039663232440876 0.8617837983670843 0.6223981892355129 0.03205086235025492 21406436.521656934 25380372.42674069 737928.4121083288 0.007706020358828364 9.068761470514187e-12 11.042452020905674 -0.14218252487700334 QQFILT(ph)SPDGAGTGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QQFILTSPDGAGTGK 15 0 C9JKS0;P49116;P49116-2;C9JMI6 C9JKS0 NR2C2 Nuclear receptor subfamily 2 group C member 2 1 QQFILT(0.499)S(0.499)PDGAGT(0.002)GK 77.77600000000001 0.030748 3498200.0 26638.0 22756.0 22634.0 27140.0 35230.0 32482.0 35484.0 31205.0 30381.0 26542.0 True False 31147.28727551795 25015.06529083523 23173.680399923003 25619.433789067178 28326.934400671093 30778.586738707014 32122.698638087066 30385.901814430486 30825.264649794823 31353.85449364362 0.9934117440594888 0.7978306238522139 0.7391014844640876 0.8171063559110736 0.9034593946467994 0.9816524072007405 1.0245215191835286 0.969128112162115 0.9831411527422902 1.0 14.936355191541294 -6.572820143508735 2.6981855689190155 0.9927919640120415 0.8279432104003361 0.5817740321358603 0.06183281065530954 0.19876692780080188 2.938893339618018 0.022760287469342784 0.023570278142154205 2.674113623092246e-07 6.572820143508735 -0.16484875361170537 QQFILTS(ph)PDGAGTGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QQFILTSPDGAGTGK 15 0 C9JKS0;P49116;P49116-2;C9JMI6 C9JKS0 NR2C2 Nuclear receptor subfamily 2 group C member 2 1 QQFILT(0.225)S(0.775)PDGAGTGK 105.17 0.0049729 0.0 31989.0 29030.0 31920.0 32758.0 42032.0 37676.0 38156.0 35013.0 33094.0 27678.0 True False 37404.10588845047 31911.906547413746 32681.093857274125 30922.67546286892 33796.13132923665 35700.20423519258 34541.5874544823 34093.94584934 33577.93714230307 32695.802301072574 1.1440033048897975 0.9760245750680627 0.9995501427472857 0.9457689760331868 1.0336535258572925 1.0918895308472503 1.0564532760631837 1.0427621728132839 1.0269800640800166 1.0 14.99681780462561 -6.514721137985516 24.854035628651467 1.0488340914386305 1.0094398889050993 0.0451126213176517 0.05309119171461475 842.6800736351051 2567436.182900859 0.01706475862259534 0.017866370779846683 3.056883318710263e-07 6.514721137985516 -0.03939420253353121 QQFS(ph)PSMTER ddPTM_PC-9_AZD4547_30min_R2 1 QQFSPSMTER 10 0 Q8TDB6 Q8TDB6 DTX3L E3 ubiquitin-protein ligase DTX3L 1 QQFS(0.741)PS(0.259)MTER 142.76 0.00012749999999999998 6704200.0 18391.0 23366.0 24928.0 31280.0 36572.0 30880.0 26981.0 34028.0 32809.0 28481.0 True False 24238.955443436127 30918.602552965905 24597.438432334144 24068.8792711825 31494.6090786716 28949.068718397666 29382.256730877165 28769.754485650366 34543.216759098985 27483.888858941704 0.8819332507069916 1.1249718957769232 0.8949766373520873 0.8757450372002886 1.1459298660504165 1.0533105000888283 1.0690720254938681 1.0467861601867274 1.2568533127312722 1.0 14.74629853365321 -6.268038923281233 24.982822845892198 1.0942512150516837 0.9537734988872558 0.3854807004947076 0.09304403076399667 590.9101039936625 2236909.1475307476 0.02829333698135393 0.032823412516083034 5.394622714916659e-07 6.268038923281233 -0.14047771616442783 QQFS(ph)PSMTER ddPTM_PC-9_Lapatinib_30min_R1 1 QQFSPSMTER 10 0 Q8TDB6 Q8TDB6 DTX3L E3 ubiquitin-protein ligase DTX3L 1 QQFS(0.994)PS(0.006)MTER 186.76 0.0014697 10480000.0 37623.0 32825.0 55293.0 36593.0 49955.0 50661.0 53393.0 44643.0 41563.0 42214.0 True False 37086.48912078682 32748.99572926199 50747.02297715237 39284.17129066954 47016.74511530882 48494.34712655904 56157.42828604453 46717.276757284075 36881.73726220688 49510.633653380755 0.749061088178063 0.6614537789706874 1.0249721975369464 0.7934491722665942 0.9496292340847138 0.9794733686113444 1.1342498397252871 0.9435806676268232 0.7449255753907821 1.0 15.595450793053525 -5.256448667096638 24.908449403289946 0.9468293744475758 0.7052574128300846 0.4507237164794191 0.10642933753819468 357.949986444252 1786497.7115164227 0.028153325524308628 0.06976912594942193 5.540530282377464e-06 5.256448667096638 -0.24157196161749117 QQFSPS(ph)MTER ddPTM_PC-9_Lapatinib_30min_R1 1 QQFSPSMTER 10 0 Q8TDB6 Q8TDB6 DTX3L E3 ubiquitin-protein ligase DTX3L 1 QQFS(0.391)PS(0.566)MT(0.042)ER 106.54 0.0023011 12301000.0 33153.0 31957.0 44302.0 33008.0 34938.0 43833.0 33237.0 34787.0 47442.0 34061.0 True False 32680.23214048442 31883.005529932216 40659.66057066541 35435.5184314601 32883.01553075085 41958.36476971364 34957.84923010999 36403.33101618712 42098.58237359235 39948.39846657035 0.8180611337356094 0.7981047239381218 1.0178045211171671 0.8870322664152176 0.8231372668986477 1.050314064650809 0.8750751111928416 0.9112588342346236 1.0538240327411703 1.0 15.285850046140732 -1.5228787452803376 0.2193718743704598 0.996635154405425 0.0363450118532061 0.3235239727712984 0.07739655147904459 66.92080368514824 0.85419042207132 0.12268748293188896 22.728458218697636 0.029999999999999995 1.5228787452803376 -0.960290142552219 QQGAGMTDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QQGAGMTDK 9 0 K7ERJ6;Q9H7M6 K7ERJ6 ZSWIM4 Zinc finger SWIM domain-containing protein 4 0 66.62100000000001 0.040244 2078100.0 13687.0 16182.0 18441.0 17203.0 22731.0 24847.0 19020.0 21701.0 19997.0 16771.0 False True 16003.93876942766 17788.442016887675 18880.703377881964 16239.171682878516 18277.023725848834 23543.979579356364 17218.28790712478 21131.371744110103 20289.418294392784 19811.44954083705 0.8078126104018273 0.8978869506857952 0.9530197847948202 0.8196861945616322 0.9225485337746071 1.1884026724458252 0.8691079303224621 1.0666242114466342 1.024125885012629 1.0 14.274046821052488 -6.5373164082297315 24.902226595592637 1.0273036592669054 0.8767723565587848 0.4613346476686453 0.08219139095152336 207.87693680711473 358545.7492822434 0.025920437160519273 0.02593067383286616 2.901907679333345e-07 6.5373164082297315 -0.15053130270812054 QQGHEPVS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 QQGHEPVSPR 10 0 Q9BTA9-2;Q9BTA9;A0A0A0MRT2;Q9BTA9-5 Q9BTA9-2 WAC WW domain-containing adapter protein with coiled-coil 1 QQGHEPVS(1)PR;QQGHEPVS(1)PR 90.759 0.0048202 101891000.0 45479.0 54556.0 57378.0 67511.0 57363.0 60930.0 55352.0 74785.0 63865.0 58695.0 True False 59940.37597803452 72190.16009927278 56617.13022988081 51947.381984552514 49399.13760745484 57120.037468004215 60278.220768967556 63228.69663833788 67240.77351701833 56640.105915367545 1.0582673709614576 1.2745414037032408 0.999594356593876 0.9171483906151771 0.8721582844719206 1.008473351962897 1.064232133658721 1.116323771230497 1.1871583294263335 1.0 15.789536342771077 -10.261321054016028 14.410790749155987 1.000006567368166 1.0513577608855647 0.0201090727446811 0.1128405678531196 0.0 0.0 0.12108488243460866 0.029367397643728713 5.478717986553963e-11 10.261321054016028 0.0513511935173987 QQGHEPVS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QQGHEPVSPR 10 0 Q9BTA9-2;Q9BTA9;A0A0A0MRT2;Q9BTA9-5 Q9BTA9-2 WAC WW domain-containing adapter protein with coiled-coil 1 QQGHEPVS(1)PR;QQGHEPVS(1)PR;QQGHEPVS(1)PR;QQGHEPVS(1)PR 86.738 0.0062759999999999995 102067800.0 96865.0 136803.0 127275.0 113438.0 136842.0 93550.0 121716.0 106472.0 99599.0 91419.0 True False 113262.33132904292 150383.8977404696 130309.71869312556 107082.43663095808 110028.79242851611 88644.07331463713 110186.17933247123 103677.22281640886 101055.4469522043 107992.54102759415 1.0487977248364055 1.3925396727357646 1.2066548064632439 0.9915725253987354 1.0188554818837132 0.8208351472347232 1.020312868685223 0.9600405901173985 0.9357632109645675 1.0 16.72057214428741 -5.769861045657198 3.853841131845175 0.957670880475855 1.2395866228360706 0.6015524109138213 0.0940941785521616 0.13048782119828828 4.235750777391374 0.02563118251070176 0.042821400401533836 1.6987870995826173e-06 5.769861045657198 0.28191574236021555 QQGHEPVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 QQGHEPVSPR 10 0 Q9BTA9-2;Q9BTA9;A0A0A0MRT2;Q9BTA9-5 Q9BTA9-2 WAC WW domain-containing adapter protein with coiled-coil 1 QQGHEPVS(1)PR;QQGHEPVS(1)PR 94.09 0.0036479 97510000.0 47842.0 69841.0 94698.0 69939.0 86664.0 91867.0 72793.0 85044.0 89534.0 66885.0 True False 47159.764306851706 69679.28745551835 86912.29598485102 75082.54736966467 81566.59390797952 87938.0625624366 76561.86536111555 88995.45470838576 79449.73808518218 78445.98313133953 0.6011750050718807 0.8882454483215108 1.107925384010251 0.9571241811573249 1.0397803769176461 1.1210014719964028 0.9759819726260621 1.1344807108782562 1.0127954920542215 1.0 16.259411954660415 -4.838594780044883 2.5225904306205145 1.045479062301064 0.5347819329938167 0.8405004074142923 0.05889626035267443 0.15197857457443628 1.3728421920978202 0.014553763905500195 0.16064650686131837 1.450124265927541e-05 4.838594780044883 -0.5106971293072472 QQLEEEEENFSRPQIDENPLDDNS(ph)EEEMEDAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QQLEEEEENFSRPQIDENPLDDNSEEEMEDAPK 33 1 Q5F1R6;Q5F1R6-3;Q5F1R6-2;A0A2R8Y534;A0A2R8Y4Q0;A0A2R8Y4N5 Q5F1R6 DNAJC21 DnaJ homolog subfamily C member 21 1 QQLEEEEENFSRPQIDENPLDDNS(1)EEEMEDAPK 62.295 0.00013129 1316300.0 5568.3 3751.6 3977.5 5676.7 5523.3 4628.2 5860.9 3668.1 5767.2 4232.7 True False 6510.903211061892 4124.034054539351 4072.338684752752 5358.652903109717 4441.049014340803 4385.489044519544 5305.7131227585505 3571.8162616732106 5851.534389529527 5000.055003965238 1.3021663173502076 0.824797737478654 0.814458777258096 1.0717187908653198 0.8882000319634241 0.8770881602385735 1.0611309512697187 0.7143553938587919 1.1702940037437655 1.0 12.28772825025173 -4.751612998415214 24.999338573531613 0.9279088645235953 1.3021670697581103 0.4064052928705121 0.1325309780785185 378.71921149983586 963434.9758209905 0.030540876296502137 0.39659829313915756 1.771687012633283e-05 4.751612998415214 0.3742582052345149 QQLPQT(ph)PPSCLK ddPTM_PC-9_AZD4547_30min_R2 2 QQLPQTPPSCLK 12 0 Q8IY81 Q8IY81 FTSJ3 pre-rRNA processing protein FTSJ3 1 QQLPQT(0.995)PPS(0.005)CLK;QQLPQT(0.909)PPS(0.091)CLK 120.84 0.0011599 36950000.0 46786.0 41249.0 53021.0 59807.0 57666.0 51738.0 44755.0 52957.0 36655.0 44991.0 True False 61662.97479074563 54581.932581840745 52317.90689669404 46019.42015893896 49660.07128761559 48502.81468110292 48738.10829807674 44773.71248079777 38592.50846733439 43415.87878419459 1.4202862297743895 1.2571882479483778 1.2050408367120329 1.0599674922552111 1.143822782776291 1.1171676363432315 1.1225871654087005 1.0312750480844233 0.8889030821917595 1.0 15.4059351653876 -1.5228787452803507 0.29140364383616946 0.9857676755655561 4.379644226476755 0.816485745667821 0.05995480424168598 23.64703335617707 0.33580547263162897 0.06763901138135826 41.42107569588367 0.02999999999999909 1.5228787452803507 3.3938765509111994 QQLPQT(ph)PPSCLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QQLPQTPPSCLK 12 0 Q8IY81 Q8IY81 FTSJ3 pre-rRNA processing protein FTSJ3 1 QQLPQT(0.999)PPS(0.001)CLK;QQLPQT(0.985)PPS(0.015)CLK;QQLPQT(0.999)PPS(0.001)CLK 166.48 0.0021357 18539800.0 103306.0 93076.0 91435.0 106243.0 117391.0 100223.0 122252.0 86881.0 91109.0 76978.0 True False 120793.66541349408 102315.97016214528 93615.15716916857 100290.54915445339 94389.07624834453 94967.12944749209 110671.40553216697 84600.46580802886 92441.2967637061 90933.50204248737 1.3283736213860429 1.1251735374091236 1.0294902875887066 1.1028998872999973 1.038001112112042 1.044357990338039 1.2170586532613399 0.9303553025869444 1.0165812894846415 1.0 16.472524294715946 -4.768806452573199 2.490330635149585 1.0524512468042175 1.3954200333705589 0.5913437468298108 0.07041649254135957 0.39529603668744806 3.0088455555776012 0.018362407945468506 0.29738482678444694 1.7029172604280436e-05 4.768806452573199 0.34296878656634133 QQLPQT(ph)PPSCLK ddPTM_PC-9_Lapatinib_30min_R1 4 QQLPQTPPSCLK 12 0 Q8IY81 Q8IY81 FTSJ3 pre-rRNA processing protein FTSJ3 1 QQLPQT(0.997)PPS(0.003)CLK;QQLPQT(0.996)PPS(0.004)CLK;QQLPQT(0.999)PPS(0.001)CLK;QQLPQT(0.997)PPS(0.003)CLK 161.21 0.0015082000000000001 40470200.0 168625.0 174814.0 190520.0 164814.0 187227.0 174639.0 170049.0 155136.0 202268.0 152197.0 True False 166220.37657796254 174409.22892353983 174856.1810284679 176934.97136338628 176214.67596244457 167170.09707339262 178853.30516385296 162344.18491181213 179486.4478635339 178504.04866024482 0.9311854707247432 0.9770603537150082 0.979564230284098 0.9912098503723855 0.9871746735439165 0.9365059130483665 1.0019565746896468 0.9094706037777859 1.0055035121649196 1.0 17.44559727090865 -5.777239640658268 0.0027297268517215405 1.935051486352564 9.529118069426668e-09 0.07438007835267069 0.030909294110933266 248459.63092721422 153.05310669560043 53512.743010285005 54987.18774873955 1.6701687725513038e-06 5.777239640658268 -1.935051476823446 QQLS(ph)AEELDAQLDAYNAR ddPTM_PC-9_AZD4547_30min_R2 2 QQLSAEELDAQLDAYNAR 18 0 E9PB61;Q86V81 E9PB61 ALYREF THO complex subunit 4 1 QQLS(1)AEELDAQLDAYNAR;QQLS(1)AEELDAQLDAYNAR 123.0 5.1858000000000004e-05 6024700.0 10461.7 9215.2 11324.2 18493.5 12740.1 12559.6 8924.8 13824.9 11882.6 14510.2 True False 13788.30298312195 12193.833186942205 11174.033708899162 14230.10929672678 10971.357025133546 11774.24622654103 9719.089910371475 11688.579369597614 12510.689977191301 14002.202314561157 0.9847238793845473 0.87085109277857 0.79801972988771 1.0162765097265176 0.7835451008820393 0.8408853094699802 0.69411151846195 0.8347672106867388 0.8934801609159151 1.0 13.773366136606613 -6.306078444713714 24.997514849611182 0.8255066000019945 0.9056063287227558 0.12243704268463806 0.0925777265585097 866.3775704195306 485162.0302859506 0.028175702981768514 0.03194845271167044 4.942214098714728e-07 6.306078444713714 0.08009972872076132 QQLS(ph)AEELDAQLDAYNAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QQLSAEELDAQLDAYNAR 18 0 E9PB61;Q86V81 E9PB61 ALYREF THO complex subunit 4 1 QQLS(1)AEELDAQLDAYNAR;QQLS(1)AEELDAQLDAYNAR 116.13 0.0001236 6575800.0 12818.8 10682.9 11275.5 14201.599999999999 14796.6 13981.9 14322.8 14851.1 11575.3 11247.900000000001 True False 14988.769657159293 11743.42771117348 11544.350682571876 13405.930394208424 11897.31244828185 13248.664550271782 12966.04069590782 14461.274361041145 11744.566864183866 13287.0552316726 1.12807310542597 0.8838247080647675 0.8688419278226068 1.0089466898769608 0.8954062612701424 0.9971106704434173 0.975840054085154 1.0883731653774973 0.8839104421112154 1.0 13.69773377961818 QQLS(ph)AEELDAQLDAYNAR ddPTM_PC-9_Lapatinib_30min_R1 2 QQLSAEELDAQLDAYNAR 18 0 E9PB61;Q86V81 E9PB61 ALYREF THO complex subunit 4 1 QQLS(1)AEELDAQLDAYNAR;QQLS(0.997)AEELDAQLDAY(0.003)NAR 168.05 1.0449000000000002e-07 4822800.0 17901.5 13522.599999999999 16595.3 11140.9 15249.7 15992.9 12543.6 13298.900000000001 19274.5 16253.5 True False 17646.221327266954 13491.289250526066 15230.898493710536 11960.238950952913 14352.742628063754 15308.92094827079 13193.046231693821 13916.815444021357 17103.602840516964 19062.89581857259 0.9256841927486484 0.707725068579653 0.7989813635172566 0.6274093435111939 0.7529151270962815 0.8030742597541566 0.6920798580266124 0.7300472906357957 0.8972195517038536 1.0 14.218479673286142 -8.45841452321226 3.230791114313787 0.9982326820153405 0.7500675416916872 0.5315635424928348 0.0755652755675547 0.16347827279050534 3.528891340427094 0.07026673514434262 0.018700752655779224 3.480049944090432e-09 8.45841452321226 -0.24816514032365333 QQLS(ph)PDRQPQSSGPDR ddPTM_PC-9_AZD4547_30min_R2 1 QQLSPDRQPQSSGPDR 16 1 A0A1B0GUA8;Q9H1H9-3;Q9H1H9-4;Q9H1H9-2;Q9H1H9;H0Y307 A0A1B0GUA8 KIF13A Kinesin-like protein KIF13A 1 QQLS(1)PDRQPQSSGPDR 54.17100000000001 0.033348 7103000.0 2697.0 2251.7 5336.5 9047.4 8954.5 6057.0 4432.0 7374.6 2477.8 4397.7 True False 3554.5898989150824 2979.5179906065796 5265.734523192846 6961.661710936589 7711.322240921053 5678.254832491403 4826.439414078341 6235.025021449308 2608.771449471044 4243.7378615557045 0.8376082630165124 0.7020975582865816 1.2408246444474045 1.6404551690156766 1.817106167366844 1.3380314754902938 1.1373085641790854 1.469229538877225 0.6147343531993512 1.0 12.051119827457233 -3.458353930699043 12.715673371577607 1.2149233422031205 1.1132818736095422 0.0 0.3797366844410609 0.0 0.0 0.0930970907180398 0.0 0.00034805355125044587 3.458353930699043 -0.10164146859357825 QQLS(ph)PDRQPQSSGPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QQLSPDRQPQSSGPDR 16 1 A0A1B0GUA8;Q9H1H9-3;Q9H1H9-4;Q9H1H9-2;Q9H1H9;H0Y307 A0A1B0GUA8 KIF13A Kinesin-like protein KIF13A 1 QQLS(0.998)PDRQPQS(0.002)SGPDR 188.0 2.1324000000000002e-07 2647800.0 15341.0 18275.0 19114.0 20768.0 24678.0 20060.0 20889.0 18556.0 20607.0 18823.0 True False 17937.92830143857 20089.22122473256 19569.750250248657 19604.436290764457 19842.523052505276 19008.01828638825 18910.242696736565 18068.924661707173 20908.338390386165 22235.460897213976 0.806726174211488 0.9034767175547805 0.8801144415540618 0.881674384056542 0.8923819094297016 0.8548515533028546 0.8504542714068927 0.8126175007225124 0.9403150439308369 1.0 14.440574688769274 -8.500775717504675 5.21505874323195 0.9998389330808928 0.8639616143163679 0.6959080289183023 0.030258679979727063 0.08507729584674673 7.45334301577019 0.029433988819472984 0.007649827019408117 3.1566343817219896e-09 8.500775717504675 -0.1358773187645249 QQLS(ph)PDRQPQSSGPDR ddPTM_PC-9_Lapatinib_30min_R1 1 QQLSPDRQPQSSGPDR 16 1 A0A1B0GUA8;Q9H1H9-3;Q9H1H9-4;Q9H1H9-2;Q9H1H9;H0Y307 A0A1B0GUA8 KIF13A Kinesin-like protein KIF13A 1 QQLS(0.991)PDRQPQS(0.008)S(0.002)GPDR 135.09 1.2835999999999999e-05 0.0 11381.0 12283.0 12901.0 12985.0 13824.0 14035.0 11520.0 14032.0 14300.0 13025.0 True False 11218.70485298021 12254.559468165271 11840.329579300138 13939.96021669018 13010.8994990297 13434.755767182967 12116.449232207086 14683.977946334475 12689.38341432424 15276.353895278437 0.7343836709915217 0.8021913836359126 0.7750756273694148 0.9125188060089846 0.8517018909237933 0.8794477962005931 0.7931505983212392 0.9612226874943601 0.8306552402040275 1.0 13.899012626791226 -1.5228787453023633 0.07114377693447788 1.136404274314152 0.18108855711976984 0.5547022655421485 0.05353398114522092 185.49913304898013 0.9769254860682475 2.2554883239218726 17.704825747106923 0.029999999998478515 1.5228787453023633 -0.9553157171943822 QQLS(ph)PSPGQEAGILPETEK ddPTM_PC-9_Lapatinib_30min_R1 1 QQLSPSPGQEAGILPETEK 19 0 E5RJM0;B7ZLQ8;Q17RY0-2;Q17RY0 E5RJM0 CPEB4 Cytoplasmic polyadenylation element-binding protein 4 1 QQLS(0.856)PS(0.144)PGQEAGILPETEK 141.6 0.00019672 4507600.0 37077.0 32407.0 40505.0 33533.0 34586.0 39791.0 34144.0 36198.0 44504.0 37878.0 True False 36548.27518091092 32331.963582580152 37174.83525382156 35999.12868280875 32551.719478692226 38089.23168735144 35911.80925212492 37879.89122729586 39491.4908721039 44425.161830737576 0.8226931242290563 0.7277849365133839 0.8367968448929871 0.8103319650239542 0.7327315903252339 0.8573796946980994 0.8083664250667444 0.8526674899152968 0.8889442209027568 1.0 15.439089411222138 -8.61131281396426 0.6160241175656181 1.003424010972576 0.7875605568710826 0.7339468131367681 0.03802953935139937 0.4659553078215319 0.4012746161290439 0.038708132806263264 0.015994485362812696 2.447299863824598e-09 8.61131281396426 -0.21586345410149343 QQMS(ph)S(ph)S(ph)S(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QQMSSSSSPK 10 0 F8W8I8 F8W8I8 SEPT8 4 QQMS(0.992)S(0.995)S(0.995)S(0.557)S(0.462)PK 58.676 0.029095 0.0 2323.2 1003.7 3247.7 1239.2 3985.4 3260.1 3304.4 3681.7 3183.1 2358.8 True False 2716.4718747084366 1103.3407027777876 3325.1374849708363 1169.7716415406069 3204.4894794332813 3089.13461692195 2991.3833102157278 3585.0592760836016 3229.6468156664314 2786.4317677494746 0.9748926588295601 0.39596903665397337 1.1933317454446264 0.4198098999156185 1.1500333568266272 1.1086345815734653 1.0735534043353903 1.2866129784972833 1.159061870111727 1.0 11.444203110773351 -6.303762012631259 24.708144722990564 1.1401246180402942 0.7529507279178882 0.4000029610767418 0.22991005588144364 397.7336920380801 232197.64508098172 0.06599148437890379 0.0748279383030531 4.968645217476071e-07 6.303762012631259 -0.387173890122406 QQPGS(ph)PRR ddPTM_PC-9_AZD4547_30min_R2 1 QQPGSPRR 8 1 P28749;P28749-2 P28749 RBL1 Retinoblastoma-like protein 1 1 QQPGS(1)PRR 66.92 0.021884 739680.0 3732.5 837.7 2871.6 2799.7 1119.4 2091.1 1142.6 1174.6 3810.0 4182.7 True False 4919.357359177063 1108.4701428836572 2833.5207077298905 2154.272419933812 963.9906322504922 1960.3431864326856 1244.2891864905037 993.0925596228072 4011.3888217308418 4036.264946114798 1.2187895058554832 0.2746276960710028 0.7020155380179794 0.5337291899054987 0.2388323475093983 0.4856824843274127 0.30827738097030116 0.24604246076034525 0.993836845520287 1.0 11.978805162748671 -8.280545574038749 23.448893404081797 0.9969189734039012 0.48557182854298764 0.3339603236156615 0.2794601355177513 460.89537807797035 565642.0404409877 0.2576296290393481 0.06708223059016563 5.241485949635453e-09 8.280545574038749 -0.5113471448609136 QQPGS(ph)PRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QQPGSPRR 8 1 P28749;P28749-2 P28749 RBL1 Retinoblastoma-like protein 1 1 QQPGS(1)PRR;QQPGS(1)PRR 79.65899999999999 0.0093519 1928200.0 1164.8400000000001 1672.41 5424.900000000001 3221.5 9536.900000000001 10706.5 2144.3 5954.0 8355.6 9160.099999999999 True False 1362.0244053613008 1838.4358122273582 5554.250190047822 3041.009799243918 7668.212906209484 10145.032292283937 1941.1763806123902 5797.713808784463 8477.784842757828 10820.753618688293 0.12587149225992703 0.16989905481742368 0.5132960592000907 0.28103493586545164 0.7086579342279706 0.9375532102276747 0.17939382496056705 0.5357957507480213 0.7834745288087908 1.0 13.401513359682994 -6.8432545280385435 0.2078809222079662 1.0320629537815698 9.820480668356296e-26 0.48848278327882855 0.22170852346671974 5.076578348970019 0.5584669241871875 0.729337911293598 1.6530223523511907 1.4346483790031414e-07 6.8432545280385435 -1.0320629537815698 QQPPEPEWIGDGES(ph)TSPSDKVVK ddPTM_PC-9_Lapatinib_30min_R1 1 QQPPEPEWIGDGESTSPSDKVVK 23 1 Q5STZ8;Q8NE71-2;Q8NE71;A0A0G2JIC2 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 QQPPEPEWIGDGES(0.489)T(0.489)S(0.021)PS(0.001)DKVVK 92.41 0.00058336 0.0 20370.0 17527.0 19920.0 13312.0 13336.0 15865.0 11559.0 9371.0 14740.0 10859.0 True False 20079.520064599503 17486.417308355678 18282.25449342366 14291.008887530208 12551.602699584795 15186.490933121328 12157.46846137863 9806.41087051742 13079.825980918831 12735.96368129202 1.5765999783820446 1.3729952240710017 1.4354826184278966 1.1220987469148023 0.9855243791266433 1.1924100376816331 0.9545778211692653 0.7699779236118702 1.0269993153428911 1.0 13.636620506465869 -5.637283784685287 0.6742960280512018 0.9318422101866785 1.6455676299439046 0.8003306184009353 0.1059951464827493 0.5686104814276361 0.3998003999617125 0.05804295379117425 0.26744433639026927 2.3052403639224498e-06 5.637283784685287 0.7137254197572261 QQPPEPEWIGDGEST(ph)SPSDKVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QQPPEPEWIGDGESTSPSDKVVK 23 1 Q5STZ8;Q8NE71-2;Q8NE71;A0A0G2JIC2 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 QQPPEPEWIGDGES(0.286)T(0.403)S(0.286)PS(0.025)DKVVK;QQPPEPEWIGDGES(0.15)T(0.396)S(0.396)PS(0.058)DKVVK 93.546 8.422999999999999e-06 24324600.0 71311.0 35665.0 57039.0 87939.0 80109.0 91341.0 89190.0 100724.0 75247.0 66612.0 True False 83382.5438435491 39205.585498226326 58399.02608161211 83012.06293208453 64412.216517268236 86550.91716335926 80741.27752031841 98080.10172589982 76347.34502166192 78688.22829969806 1.059657151333639 0.49823952509014313 0.7421570842742712 1.054948938689004 0.8185750004682135 1.0999220472179747 1.0260909320870835 1.2464393193902443 0.9702511629932692 1.0 16.263860205321535 -6.234179076695565 1.0974863681270768 1.0809710013618523 0.751341539994214 0.31548821608362265 0.16683492994706545 0.5334161023851052 1.3348142434707375 0.07000443679056613 0.1085441790756256 5.832045765034637e-07 6.234179076695565 -0.32962946136763827 QQPPEPEWIGDGEST(ph)SPSDKVVK ddPTM_PC-9_Lapatinib_30min_R1 1 QQPPEPEWIGDGESTSPSDKVVK 23 1 Q5STZ8;Q8NE71-2;Q8NE71;A0A0G2JIC2 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 QQPPEPEWIGDGES(0.173)T(0.441)S(0.369)PS(0.017)DKVVK 83.411 4.256e-05 41298000.0 254770.0 151700.0 197810.0 157630.0 146120.0 152400.0 119690.0 117000.0 174470.0 120250.0 True False 251136.9330809035 151348.7479704204 181546.82536868134 169222.63603826507 137525.50888297314 145882.20726175146 125886.96255233235 122436.2471294995 154819.35134945114 141035.0522769466 1.780670330009542 1.0731285983658947 1.287246130927671 1.1998622562706418 0.9751158074725859 1.0343684417919499 0.8925934405663326 0.8681263639983261 1.0977366892128113 1.0 17.10569424317012 -1.5228787452803376 0.6205766473756338 0.979446275674864 52.150234311308296 0.7518896252965671 0.12516240780154497 95.27962890810986 0.6859132684484315 0.05514081968723801 6649.63320117024 0.029999999999999995 1.5228787452803376 51.17078803563343 QQPPEPEWIGDGESTS(ph)PSDKVVK ddPTM_PC-9_AZD4547_30min_R2 3 QQPPEPEWIGDGESTSPSDKVVK 23 1 Q5STZ8;Q8NE71-2;Q8NE71;A0A0G2JIC2 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 QQPPEPEWIGDGES(0.2)T(0.2)S(0.577)PS(0.024)DKVVK;QQPPEPEWIGDGES(0.052)T(0.269)S(0.665)PS(0.014)DKVVK;QQPPEPEWIGDGES(0.296)T(0.296)S(0.404)PS(0.004)DKVVK 106.62 9.7553e-07 130609000.0 594791.0 405849.0 649563.0 929057.0 786776.0 712306.0 537223.0 645593.0 512832.0 729869.0 True False 783922.1655786426 537031.7524402406 640949.3702030752 714877.2624375639 677545.7331423191 667765.3932165451 585034.8062611491 545831.4361012846 539939.2525527221 704316.5084648344 1.113025402865142 0.7624863906864592 0.9100303095267814 1.0149943297449442 0.9619904190789645 0.9481041338531763 0.8306419049247078 0.7749803242451433 0.7666145064945337 1.0 19.42586437286934 -7.272913932335666 7.028915102421105 0.8239114497148844 0.9447171657343005 0.2026464802945881 0.10232574595498944 0.22897278441977276 67.39371489221087 0.040922549575925 0.028778810482178164 5.334406012689508e-08 7.272913932335666 0.12080571601941614 QQPPEPEWIGDGESTS(ph)PSDKVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QQPPEPEWIGDGESTSPSDKVVK 23 1 Q5STZ8;Q8NE71-2;Q8NE71;A0A0G2JIC2 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 QQPPEPEWIGDGES(0.054)T(0.177)S(0.591)PS(0.177)DKVVK 88.95100000000001 1.1342e-05 3076200.0 23505.0 15674.0 24061.0 34719.0 33989.0 38875.0 35475.0 36425.0 29605.0 26108.0 True False 27483.93225508856 17230.011134142715 24634.705491850626 32773.80699051672 27329.099442078033 36836.32656447375 32114.551183241405 35468.88234547768 30037.917117842586 30841.173729185713 0.8911441729300944 0.5586691117996446 0.7987603101025379 1.0626640632519804 0.8861238447684588 1.194387959677899 1.0412882293403336 1.1500496919127516 0.973955057015778 1.0 14.912570050802831 -5.679437337444649 4.0267112400701635 1.050782106937789 0.7150249065830917 0.5995483300151827 0.1108917978755473 0.1319124547726048 4.0535733157757825 0.029529673831661437 0.052594152088638824 2.092004732041895e-06 5.679437337444649 -0.33575720035469725 QQPPEPEWIGDGESTS(ph)PSDKVVK ddPTM_PC-9_Lapatinib_30min_R1 1 QQPPEPEWIGDGESTSPSDKVVK 23 1 Q5STZ8;Q8NE71-2;Q8NE71;A0A0G2JIC2 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 QQPPEPEWIGDGES(0.084)T(0.22)S(0.683)PS(0.013)DKVVK 94.271 4.9648e-06 53287000.0 294750.0 177640.0 192940.0 178590.0 178040.0 175820.0 136430.0 125000.0 219100.0 137710.0 True False 290546.8109494699 177228.6854941688 177077.2179699382 191724.10435877522 167568.03724010754 168300.58845643824 143493.6778428833 130807.95633493502 194422.65077471614 161512.99001295923 1.7989067685896811 1.0973029815121904 1.0963651775360617 1.1870506783596289 1.0374895370747732 1.0420250931082038 0.8884342852631846 0.8098912435739036 1.2037586002160963 1.0 17.30129067572524 -2.5980715704374546 1.2491591949803893 1.0147671776914033 199.99767262581466 0.7911143965080094 0.11656109810294359 171.18220870415252 1.395453420244985 0.03569240284214717 96421.6609735893 0.0025230649446277686 2.5980715704374546 198.98290544812326 QQPPLGPSSS(ph)LLSLPGLK ddPTM_PC-9_AZD4547_30min_R2 1 QQPPLGPSSSLLSLPGLK 18 0 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 QQPPLGPS(0.045)S(0.185)S(0.77)LLSLPGLK 176.28 2.0326e-08 186930000.0 239840.0 258060.0 289050.0 422480.0 420600.0 467760.0 341730.0 461300.0 368900.0 371580.0 True False 316104.1310180915 341472.8483616528 285217.00813808525 325083.7632509326 362206.9500844703 438510.8932551055 372143.3079812698 390016.68461944646 388399.30087572394 358571.0973001488 0.8815661200754574 0.952315596356659 0.795426653976349 0.9066089422673547 1.010139837850004 1.222939875960057 1.0378508217291147 1.0876969380858255 1.083186301964006 1.0 18.451899678587807 -6.368556418551661 3.40165956909646 1.0905464264266702 0.8812943561413901 0.6783967767099454 0.06532038832799673 0.14012017401803079 3.0331456640086047 0.020695137468764852 0.02390312277830925 4.2799981515369305e-07 6.368556418551661 -0.20925207028528015 QQPPLGPSSS(ph)LLSLPGLK ddPTM_PC-9_Lapatinib_30min_R1 2 QQPPLGPSSSLLSLPGLK 18 0 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 QQPPLGPSS(0.075)S(0.871)LLS(0.054)LPGLK;QQPPLGPS(0.008)S(0.224)S(0.753)LLS(0.015)LPGLK 260.11 1.2112999999999998e-65 213804000.0 1144970.0 923920.0 889510.0 922510.0 984330.0 981380.0 808540.0 889960.0 1085110.0 847710.0 True False 1128642.517838216 921780.7200054777 816377.921407895 990354.4628031452 926433.6446672389 939408.6651085156 850402.2449833964 931310.79055871 962893.4850851303 994235.5439974269 1.1351862490254492 0.9271250918060754 0.8211111806821583 0.9960964167719478 0.9318049935555679 0.9448552415773891 0.8553327731216148 0.9367104165420184 0.9684762236659911 1.0 19.923228155098336 -4.7615687692598385 9.854711068911206 0.9258927445365857 1.1361155967042833 0.5642026883842031 0.05357548111812087 0.0521255582130149 102.15675747190984 0.013017126140778528 0.07352412527661258 1.7315348255702284e-05 4.7615687692598385 0.21022285216769765 QQPPLGPSSSLLS(ph)LPGLK ddPTM_PC-9_AZD4547_30min_R2 1 QQPPLGPSSSLLSLPGLK 18 0 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 QQPPLGPS(0.001)S(0.045)S(0.15)LLS(0.805)LPGLK 191.51 2.7664e-11 191370000.0 601640.0 685380.0 756780.0 1128000.0 1143700.0 1162600.0 875450.0 1154500.0 939470.0 984900.0 True False 792949.0051105919 906915.681663605 746744.6027287315 867957.0274262732 984916.9966990236 1089902.438212732 953363.3540286287 976098.5527707554 989128.4662339813 950418.9507802282 0.8343152295728484 0.9542272709514998 0.7857004556945185 0.9132362383070545 1.0362977252194676 1.1467600023316007 1.0030980056174 1.0270192444810218 1.0407288968953905 1.0 19.858204077330626 -6.190924310015414 3.749802686601387 1.0476628623320272 0.865993153355692 0.7023046570893163 0.05498676756283766 0.13041935192304438 3.5962030111927783 0.016661171183564062 0.021658587504989498 6.442815428127701e-07 6.190924310015414 -0.18166970897633516 QQPPLGPSSSLLS(ph)LPGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QQPPLGPSSSLLSLPGLK 18 0 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 QQPPLGPSS(0.042)S(0.042)LLS(0.916)LPGLK;QQPPLGPSSS(0.002)LLS(0.998)LPGLK 148.96 4.1194e-05 333670000.0 795170.0 971380.0 1050870.0 1192600.0 1687890.0 1303050.0 1294850.0 1033060.0 1131850.0 1091980.0 True False 929776.5756766119 1067812.1867732236 1075926.726246667 1125782.4884613685 1357160.0711197485 1234715.7641115757 1172192.4340978218 1005943.2696175487 1148401.1650001733 1289947.3298910751 0.7207864647893208 0.8277951835935744 0.8340857811128767 0.8727352368382599 1.0521050276016688 0.9571830845340303 0.9087134078542597 0.7798328244165534 0.8902698105488894 1.0 20.298880729192668 -5.139912830785515 1.2353554785033007 0.9189772554144965 0.7105109005029886 0.44334573761619867 0.07116748759377702 0.9249607350389779 1.854293574816917 0.024644397794251344 0.20969221379636357 7.245813794944218e-06 5.139912830785515 -0.2084663549115079 QQPTQFINPET(ph)PGYVGFANLPNQVHR ddPTM_PC-9_AZD4547_30min_R2 2 QQPTQFINPETPGYVGFANLPNQVHR 26 0 Q15019-2;Q15019-3;Q15019;C9J938;C9JB25;C9JT15;C9JSE7;C9JZI2;F8WB65;C9JFT1;A0A1B0GXJ2;C9IZU3 Q15019-2 SEPT2 Septin-2 1 QQPTQFINPET(0.996)PGY(0.004)VGFANLPNQVHR;QQPTQFINPET(0.994)PGY(0.006)VGFANLPNQVHR 95.209 9.6976e-09 10408100.0 19675.2 16441.4 19632.1 30789.0 26168.2 25068.0 21908.3 32875.0 24472.0 25062.0 True False 25931.50433041678 21755.761020899332 19371.765526613737 23691.071735308113 22535.19712601155 23500.493997175912 23858.096257999194 27794.924142346164 25765.53995942182 24184.58700827911 1.0722326712273254 0.8995713267070338 0.8009963337385997 0.9795938101898514 0.9317999566540902 0.9717136781840015 0.9865000485570355 1.149282563015491 1.0653702687005364 1.0 14.561800281145715 -7.508385535376509 3.19244691785702 1.0802809474083548 0.9359625949378614 0.3718110052540903 0.07327493512951197 0.24579630167034486 5.156937864365003 0.03720944163569619 0.02149006587281107 3.1018048065501616e-08 7.508385535376509 -0.1443183524704934 QQPTQFINPET(ph)PGYVGFANLPNQVHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QQPTQFINPETPGYVGFANLPNQVHR 26 0 Q15019-2;Q15019-3;Q15019;C9J938;C9JB25;C9JT15;C9JSE7;C9JZI2;F8WB65;C9JFT1;A0A1B0GXJ2;C9IZU3 Q15019-2 SEPT2 Septin-2 1 QQPTQFINPET(0.998)PGY(0.002)VGFANLPNQVHR 109.56 1.0043e-09 3007100.0 13600.0 13140.0 16345.0 14289.0 16487.0 10862.0 14114.0 14078.0 10642.0 8890.6 True False 15902.211387755995 14444.45236076529 16734.72678875769 13488.433655563045 13256.490702919786 10292.377598541834 12777.019743488921 13708.467416873984 10797.61911731399 10502.395402049126 1.5141508940573034 1.3753483665209394 1.59341999116626 1.2843197327089126 1.2622349659710306 0.9800028664445147 1.216581480163658 1.3052705494404944 1.028110131447466 1.0 13.358430797014302 -6.125255365602183 2.117334597478095 1.1361843325486964 1.4804851811940956 0.6631378188660768 0.11508943075075646 0.20309656355854713 1.7932528052586303 0.03707645235898852 0.05288395127337699 7.494534003765996e-07 6.125255365602183 0.3443008486453991 QQPTQFINPET(ph)PGYVGFANLPNQVHR ddPTM_PC-9_Lapatinib_30min_R1 1 QQPTQFINPETPGYVGFANLPNQVHR 26 0 Q15019-2;Q15019-3;Q15019;C9J938;C9JB25;C9JT15;C9JSE7;C9JZI2;F8WB65;C9JFT1;A0A1B0GXJ2;C9IZU3 Q15019-2 SEPT2 Septin-2 1 QQPTQFINPET(0.999)PGY(0.001)VGFANLPNQVHR 92.39 4.7775e-07 3241500.0 16165.0 15466.0 21592.0 17298.0 14307.0 17201.0 11985.0 10677.0 18798.0 10369.0 True False 15934.484135702052 15430.18942722821 19816.789107530305 18570.152624436396 13465.490388644235 16465.353327489433 12605.524656944612 11173.092398304821 16680.771288284406 12161.267834175977 1.3102650441529184 1.2687977633274228 1.6295002608067346 1.5269915010217907 1.1072439627390733 1.3539174987346285 1.0365304694236048 0.918744044671547 1.3716309447118318 1.0 13.5700060197398 -6.680723293501285 1.4831085035715759 1.0923620776187624 1.4240963755748584 0.40291598242269255 0.1707756962946895 0.40849356054798763 1.8683914197264981 0.07589723592394487 0.07359134174505673 2.085819419345608e-07 6.680723293501285 0.331734297956096 QQQEPTGEPS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 QQQEPTGEPSPK 12 0 F5H2U8;F5H2A4;F5H6H0;P52926-3;P52926-6;P52926-4;P52926-5;P52926-2;P52926 F5H2U8 HMGA2 High mobility group protein HMGI-C 1 QQQEPTGEPS(1)PK;QQQEPT(0.015)GEPS(0.985)PK 182.37 0.00060291 53895000.0 354330.0 325450.0 273850.0 292830.0 284170.0 302530.0 363490.0 306100.0 292270.0 320360.0 True False 466999.5694781528 430645.34797837696 270218.57006958884 225322.56767840034 244717.9006312504 283612.75127515715 395839.90582656406 258799.27847824118 307718.7955189689 309144.29390999506 1.5106200524410005 1.393023764183582 0.8740855820171174 0.7288588924885712 0.791597663136872 0.9174122144972495 1.2804373673538019 0.8371471949392945 0.9953888898514129 1.0 18.2379208514609 -5.202035951626655 4.688390891311579 0.9221497643729996 1.4747375030740286 0.6801333689942846 0.14410503274663602 0.1264603088445496 5.763727179921672 0.04014568026717363 0.11239830561982711 6.280063692394071e-06 5.202035951626655 0.5525877387010291 QQQEPTGEPS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 QQQEPTGEPSPK 12 0 F5H2U8;F5H2A4;F5H6H0;P52926-3;P52926-6;P52926-4;P52926-5;P52926-2;P52926 F5H2U8 HMGA2 High mobility group protein HMGI-C 1 QQQEPT(0.02)GEPS(0.98)PK;QQQEPTGEPS(1)PK;QQQEPTGEPS(1)PK;QQQEPTGEPS(1)PK;QQQEPT(0.004)GEPS(0.996)PK 184.48 0.00048165 39953000.0 252783.0 294948.0 203886.0 235397.0 239839.0 175825.0 263276.0 244222.0 163240.4 161348.3 True False 295574.169208171 324228.48819657497 208747.41548196052 222208.46925737083 192844.2696486677 166604.42747777732 238336.59132682325 237811.43127459835 165627.4820295043 190599.46955756037 1.550760712473592 1.7010985862091244 1.095215091450816 1.1658399143144764 1.0117775778511775 0.8741075086122597 1.2504577892062099 1.2477024822085359 0.8689818624048445 1.0 17.5401845786388 -5.267715556473208 24.264514695371528 1.0747189690475765 1.625929672989485 0.7444724707970225 0.13150990633857002 146.93912460078525 568089.1181915299 0.03492966205274983 0.07578598967404127 5.398640936652559e-06 5.267715556473208 0.5512107039419085 QQQEPTGEPS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 QQQEPTGEPSPK 12 0 F5H2U8;F5H2A4;F5H6H0;P52926-3;P52926-6;P52926-4;P52926-5;P52926-2;P52926 F5H2U8 HMGA2 High mobility group protein HMGI-C 1 QQQEPTGEPS(1)PK;QQQEPTGEPS(1)PK;QQQEPT(0.005)GEPS(0.995)PK 159.41 0.00052418 64684000.0 51627.0 64472.0 54831.0 68896.0 74013.0 57898.0 64708.0 58868.0 53205.0 60330.0 True False 50890.7895127677 64322.71904514785 50323.006833780775 73962.84167031846 69659.7008551567 55421.83750683002 68058.2636213243 61603.222188199725 47212.49262651199 70757.96011532804 0.7192235252375996 0.9090527615593861 0.7111992311785071 1.045293583220415 0.984478647230908 0.783259401719584 0.9618460383877161 0.8706189676439647 0.6672393120090034 1.0 16.110604836651863 -4.0126273827783745 1.3246613432738688 0.884704911535354 1.6885341182134664e-10 0.13135717455522733 0.12046138782346141 19.584142884580917 6.753640289318846 0.03448446304854851 38.291573222090015 9.71343005477916e-05 4.0126273827783745 -0.8847049113665006 QQQLEEEAAKPPEPEKPVS(ph)PPPIESK ddPTM_PC-9_AZD4547_30min_R2 2 QQQLEEEAAKPPEPEKPVSPPPIESK 26 2 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;C9JE98;C9JQE8;C9J330;H7C1Y3;H0YGK8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 QQQLEEEAAKPPEPEKPVS(0.996)PPPIES(0.004)K;QQQLEEEAAKPPEPEKPVS(1)PPPIESK 74.561 2.7238000000000002e-05 54601000.0 196065.0 173665.0 154218.0 173595.0 171966.0 199154.0 199834.0 165273.0 192258.0 202088.0 True False 258409.59159465582 229798.81504582826 152172.96855574875 133575.3547660144 148091.4892492298 186700.86889714294 217618.83887024596 139733.85544571778 202420.36537751387 195012.96063079944 1.3250893210317418 1.1783771412038904 0.7803223337747495 0.6849562938480825 0.7593930617237187 0.9573767214918959 1.1159198761268192 0.7165362496611872 1.037984166399782 1.0 17.573210483624116 -5.106312175303062 4.077521310827566 0.8720249780035783 1.2975481415266554 0.5396045730235289 0.13909503912436527 0.1670005901688323 4.6824742039145635 0.03752751416088864 0.11806928083687647 7.828667078945136e-06 5.106312175303062 0.4255231635230772 QQQLEEEAAKPPEPEKPVS(ph)PPPIESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QQQLEEEAAKPPEPEKPVSPPPIESK 26 2 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;C9JE98;C9JQE8;C9J330;H7C1Y3;H0YGK8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 QQQLEEEAAKPPEPEKPVS(0.983)PPPIES(0.017)K;QQQLEEEAAKPPEPEKPVS(0.999)PPPIES(0.001)K 59.788999999999994 0.00085582 53526000.0 122128.0 136128.0 83500.0 116896.0 130519.0 104946.0 141662.0 102010.0 93832.0 94721.0 True False 142801.85826204906 149641.88820138952 85490.95667551352 110346.69610194558 104944.73888848085 99442.44701312561 128242.74981593627 99332.34558852918 95204.11548729612 111893.16748897635 1.2762339423103544 1.3373639477685906 0.7640409025326416 0.9861790364708093 0.9379012252809801 0.8887267135674091 1.146117789797761 0.8877427265459737 0.8508483370682627 1.0 16.77176241843012 -5.247318135014728 24.92680613946416 0.9368334889993181 1.3067990152971256 0.7040528745763014 0.09698938623850273 404.8146933118775 714575.6041197691 0.024432377453215828 0.06395878091462673 5.658246519918996e-06 5.247318135014728 0.36996552629780755 QQQLEEEAAKPPEPEKPVS(ph)PPPIESK ddPTM_PC-9_Lapatinib_30min_R1 2 QQQLEEEAAKPPEPEKPVSPPPIESK 26 2 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;C9JE98;C9JQE8;C9J330;H7C1Y3;H0YGK8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 QQQLEEEAAKPPEPEKPVS(1)PPPIESK;QQQLEEEAAKPPEPEKPVS(0.997)PPPIES(0.003)K 72.654 4.8851000000000004e-05 39519000.0 146932.0 162006.0 133195.0 162517.0 158279.0 175522.0 146563.0 165148.0 152711.0 145928.0 True False 144836.7227359715 161630.88506061875 122244.22124756842 174469.04232081908 148969.340408487 168015.3332217664 154151.31500173354 172821.37898241516 135511.07906187882 171151.4603631627 0.8462488279600155 0.9443733913672577 0.7142458556192331 1.0193838951219982 0.8703947958865912 0.9816763050999283 0.9006719234217639 1.009756963894489 0.7917611615719824 1.0 17.384914076744856 -5.782420509029708 24.999669960206703 0.9368097674150819 0.8458975991554766 0.23727751673258557 0.08481251732868986 355.9979560023988 424181.3773241249 0.02227972163446827 0.033084068340360644 1.6503630474205216e-06 5.782420509029708 -0.09091216825960535 QQQLEEEAAKPPEPEKPVS(ph)PPPVEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QQQLEEEAAKPPEPEKPVSPPPVEQK 26 2 O75376-2;O75376;A0A088AWL3;O75376-3;E7EVU5;E7EW50;J3KS51 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 QQQLEEEAAKPPEPEKPVS(1)PPPVEQK;QQQLEEEAAKPPEPEKPVS(1)PPPVEQK 54.261 0.0017305999999999997 67654000.0 198019.0 241250.0 149128.0 233030.0 240070.0 159429.0 208959.0 185897.0 178358.0 171030.0 True False 231539.70564647415 265199.7056342941 152683.77709108972 219974.08459345347 193030.00685691464 151068.2625812859 189164.89078784894 181017.4007241525 180966.14832981487 202036.38512726483 1.1460297386563558 1.3126333925804603 0.7557241582743258 1.0887845001527299 0.955421998544089 0.7477280019939301 0.9362912065007103 0.8959643611230114 0.8957106820923488 1.0 17.624255608580377 -5.25373016858989 24.999726047279687 0.9089665986226274 1.2293315869636285 0.6042335922616455 0.10355222625985637 370.1094883106158 1200198.2064562547 0.02576329957687987 0.06547409453302054 5.575320414547603e-06 5.25373016858989 0.32036498834100113 QQQQMEQER ddPTM_PC-9_AZD4547_30min_R2 1 QQQQMEQER 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 106.04 0.034657 1645000.0 2202.5 947.54 3620.4 3237.4 4553.7 3304.6 2627.4 3746.2 1254.7 2710.7 False True 2902.8491851540484 1253.8137748453876 3572.3911304726653 2491.0674473313993 3921.497357583587 3097.9628395989907 2861.2335100517676 3167.3108691120046 1321.0208804791823 2615.799218072867 1.1097370031682552 0.47932339996993634 1.3656977591363249 0.9523159996838897 1.4991583950669825 1.1843274583900776 1.0938276494171135 1.2108386787596992 0.505016161543322 1.0 11.353036092238398 -8.246310236028478 24.872606339081972 0.7525080348936709 1.1086776613623675 0.20982511531836645 0.27891867592851466 1033.5698634129496 1699216.6161187757 0.18903449875427839 0.07084154626906282 5.671393276112726e-09 8.246310236028478 0.35616962646869654 QQQQMEQER ddPTM_PC-9_Lapatinib_30min_R1 3 QQQQMEQER 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ;; 123.35 0.001042 1172600.0 7534.1 6399.1 6163.07 5259.4 2914.35 5831.099999999999 3082.69 4326.1 4252.2 4424.2 False True 7426.662352415274 6384.283277109535 5656.366174738182 5646.193820844079 2742.933662832554 5581.717445958001 3242.296604481987 4527.106399204506 3773.272458348917 5188.917075124057 1.4312547772287758 1.2303691087522148 1.0900860608960394 1.0881256607302958 0.5286138944062766 1.0756998743951893 0.6248503411291207 0.8724568794725384 0.7271791789539641 1.0 12.34121776479328 -5.481288995778527 1.0891315744370325 0.8030414266913725 1.4293648280519902 0.6034308462175073 0.16700785340377325 0.45613803549167475 0.8939691410057242 0.055285596087378486 0.25210621389997545 3.301497739265124e-06 5.481288995778527 0.6263234013606177 QQQQQQGEDGS(ph)PQAHR ddPTM_PC-9_Lapatinib_30min_R1 1 QQQQQQGEDGSPQAHR 16 0 A0A087WUX9;E9PEG3;A0A087WZ66;F5GZG9;P10275-3;P10275-4;P10275 A0A087WUX9 AR Androgen receptor 1 QQQQQQGEDGS(1)PQAHR 101.38 0.00093303 1241800.0 5019.3 4720.5 5706.7 4534.3 5154.5 5595.9 4164.0 5762.0 5240.6 4572.5 True False 4947.723861573113 4709.569972276656 5237.517154499034 4867.767547981382 4851.322444136906 5356.576401680025 4379.591545391521 6029.723555215171 4650.348442035498 5362.850532526731 0.9225921609346012 0.8781840820869794 0.9766293359720685 0.9076828672470781 0.9046163816635747 0.9988300753846016 0.8166536655885611 1.1243504771657769 0.8671411619306246 1.0 12.388784329374072 -7.7496088288698575 24.999993668304906 0.9968094138337026 0.9185195823130459 0.20311235993705146 0.07432917264487884 333.88712649447484 705564.0918169033 0.032336121358536654 0.018478464291395734 1.779881836410778e-08 7.7496088288698575 -0.07828983152065672 QQQQQQHGS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QQQQQQHGSPTR 12 0 Q6P1L5;Q6P1L5-2 Q6P1L5 FAM117B Protein FAM117B 1 QQQQQQHGS(0.988)PT(0.012)R 71.08 0.01601 319940.0 606.56 840.71 570.24 745.94 959.61 2242.1 637.14 827.59 1042.4 881.78 True False 709.2386278939168 924.1701327411716 583.8366842472428 704.1474001701092 771.5813091180235 2124.5203290085287 576.7854867058616 805.8666394040871 1057.643127972948 1041.639733833361 0.6808866874575072 0.8872262671279953 0.560497708837059 0.675998982468498 0.7407372088990022 2.0395922505663595 0.5537283841729239 0.7736519770020674 1.0153636556093077 1.0 10.024640671602976 -6.5613671418145385 24.999948584848458 1.0697062443965237 0.7048894016793669 0.19950597484334065 0.3684940576585173 286.94686701342323 186383.09948216958 0.12398769334897414 0.12398789558224661 2.7455721329705487e-07 6.5613671418145385 -0.36481684271715686 QQQQQQQHQQPNR ddPTM_PC-9_AZD4547_30min_R2 2 QQQQQQQHQQPNR 13 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;C9JH18 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 0 ; 205.07 7.469400000000001e-10 2931200.0 1325.55 1991.09 1890.91 2968.1000000000004 2659.06 3742.6 2536.02 1701.93 2028.08 4145.7 False True 1747.0473268471965 2634.670904612895 1865.8352979013534 2283.850401687876 2289.895417716629 3508.574630358648 2761.720867078284 1438.935824960707 2135.2801683926205 4000.560304852872 0.43670066033698934 0.6585754753945122 0.4663934938408516 0.5708826333444982 0.5723936756905965 0.8770208078359869 0.690333517464587 0.3596835731272963 0.5337452770809187 1.0 11.965986357767756 -6.5411202699669495 24.93247140547322 0.6600989363525919 0.5416187995495113 0.1495973069098937 0.17347002551281393 615.2024385960332 840851.3798661457 0.058705751245080456 0.058715264391398826 2.8766016818437525e-07 6.5411202699669495 -0.11848013680308056 QQQQQQQHQQPNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 QQQQQQQHQQPNR 13 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;C9JH18 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 0 ;;;; 175.74 1.9669e-26 2412370.0 1351.25 1737.3899999999999 3867.8199999999997 1468.94 2193.6 1247.6 2426.62 741.16 2149.5 1384.56 False True 1579.9899365959777 1909.866597189498 3960.043497589036 1386.6400541677363 1763.7798268893566 1182.1736597257218 2196.752986392595 721.7053353239321 2180.9323710455214 1635.56976782907 0.9660180615181798 1.1677072019523254 2.4212012079712713 0.8478024486893372 1.0783886212512126 0.722790114477873 1.3431117581174155 0.4412562212383446 1.3334389115912333 1.0 10.675577585846282 QQQQQQQHQQPNR ddPTM_PC-9_Lapatinib_30min_R1 4 QQQQQQQHQQPNR 13 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;C9JH18 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 0 ;;; 142.89 8.8665e-06 3130800.0 350.71 0.0 361.41 484.84 403.61 0.0 0.0 0.0 501.34 0.0 False True 345.7088110876629 0.0 331.69626488294404 520.4967509788269 379.87045332779076 0.0 0.0 0.0 444.87380985575606 0.0 0.0 QQQS(ph)QTAY ddPTM_PC-9_AZD4547_30min_R2 1 QQQSQTAY 8 0 Q99613-2;Q99613;B5ME19 Q99613-2 EIF3C;EIF3CL Eukaryotic translation initiation factor 3 subunit C;Eukaryotic translation initiation factor 3 subunit C-like protein 1 QQQS(0.938)QT(0.062)AY 76.221 0.025263 4806600.0 22995.0 19904.0 31023.0 40828.0 29932.0 29898.0 34940.0 55642.0 36496.0 34277.0 True False 30306.931674287083 26337.578756065814 30611.614749931883 31415.735386311993 25776.45846392865 28028.473333635146 38049.59231225116 47043.80742595972 38425.10405193932 33076.972663106826 0.9162547003006302 0.7962511873235015 0.9254660352903233 0.9497766227364655 0.7792871108993304 0.8473711793128322 1.1503347872790868 1.4222525109872322 1.161687450762314 1.0 15.01353957887776 -7.336954274604367 4.418642188005057 1.2287041044921163 0.8676511068420556 0.657398070082637 0.11034392231811553 0.12248682260096355 4.513826540435736 0.046221113210401864 0.030682604029992126 4.603050349888472e-08 7.336954274604367 -0.3610529976500607 QQQSQT(ph)AY ddPTM_PC-9_AZD4547_30min_R2 1 QQQSQTAY 8 0 Q99613-2;Q99613;B5ME19 Q99613-2 EIF3C;EIF3CL Eukaryotic translation initiation factor 3 subunit C;Eukaryotic translation initiation factor 3 subunit C-like protein 1 QQQS(0.011)QT(0.989)AY 131.06 0.009606299999999998 5968100.0 25290.0 17530.0 29170.0 37866.0 29402.0 29480.0 34739.0 49070.0 33964.0 33142.0 True False 33331.693935321615 23196.22968216607 28783.186740660596 29136.578723868173 25320.03981546271 27636.610939713824 37830.70370163974 41487.3590164236 35759.26770111977 31981.708667639687 1.04221116769311 0.7252967601958334 0.8999890230938324 0.9110388386893685 0.7917037853916321 0.8641380367421583 1.182885632996785 1.2972214664190878 1.118116235525038 1.0 14.964959398432697 -7.260575516794611 24.86487255707492 1.1743243034026185 0.8650527743094449 0.6262767123743038 0.10409530768288032 41.15105461149437 1184488.6561470618 0.03940189943559742 0.0287102414312586 5.4881311757435155e-08 7.260575516794611 -0.30927152909317357 QQQSQT(ph)AY ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QQQSQTAY 8 0 Q99613-2;Q99613;B5ME19 Q99613-2 EIF3C;EIF3CL Eukaryotic translation initiation factor 3 subunit C;Eukaryotic translation initiation factor 3 subunit C-like protein 1 QQQS(0.009)QT(0.991)AY 82.279 0.040819 3940900.0 25637.0 24678.0 16014.0 20434.0 22570.0 22548.0 29947.0 36192.0 27720.0 20111.0 True False 29976.837746169156 27127.868748779758 16395.834493433205 19289.149227921847 18147.570520100646 21365.54318651458 27110.203362495577 35241.99834859374 28125.352558912222 23756.9651014116 1.2618125934102578 1.141891173092975 0.6901485279556602 0.8119365897782844 0.7638842100678234 0.899338071816466 1.1411475854247366 1.4834385704636877 1.1838781779934113 1.0 14.536062926428926 -7.395637522864246 4.093245745300295 1.259665156884784 0.9150747153711666 0.3174919326116411 0.19534966259999811 0.26195386994010206 7.408262190461637 0.09221455236410642 0.05971302036929613 4.0212629928673035e-08 7.395637522864246 -0.3445904415136175 QQQSQT(ph)AY ddPTM_PC-9_Lapatinib_30min_R1 1 QQQSQTAY 8 0 Q99613-2;Q99613;B5ME19 Q99613-2 EIF3C;EIF3CL Eukaryotic translation initiation factor 3 subunit C;Eukaryotic translation initiation factor 3 subunit C-like protein 1 QQQS(0.001)QT(0.999)AY 145.16 0.0035957000000000003 4097000.0 24631.0 22169.0 24008.0 18041.0 34919.0 30018.0 40585.0 32212.0 40107.0 32605.0 True False 24279.757423227806 22117.669042559293 22034.15491356001 19367.795323011742 32865.1330733954 28734.200115375734 42686.29271606987 33708.687115687455 35589.727314566575 38240.730806568405 0.6349187609944265 0.5783798733982422 0.5761959682469071 0.5064703240369308 0.859427431960854 0.7514030069331262 1.1162520123370099 0.8814864780224727 0.9306759197304231 1.0 15.222822474022335 -6.592076550486354 1.5911363447380111 0.961227213666794 0.5741128397703903 0.7774319110752637 0.09190758473436891 0.16882211058844926 0.8782111510838956 0.03614545163188725 0.03761494533145999 2.5581349400445326e-07 6.592076550486354 -0.3871143738964037 QQS(ph)ASYIPK ddPTM_PC-9_AZD4547_30min_R2 1 QQSASYIPK 9 0 O95835 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 QQS(0.987)AS(0.007)Y(0.005)IPK 90.65700000000001 0.004763 19306000.0 5081.0 0.0 32284.0 50745.0 31341.0 16213.0 4999.7 44735.0 17524.0 24325.0 True False 6696.652308634608 0.0 31855.89306600915 39046.52425243464 26989.843135039006 15199.19854700069 5444.663614297718 37822.23365803363 18450.282864044955 23473.389153953754 0.2852869802785446 0.0 1.3571066733089747 1.6634378613306384 1.149805976376997 0.6475076286306362 0.23195046861738083 1.6112813284000371 0.7860084772180105 1.0 14.518738536817601 -5.25546752278382 24.962322632922366 1.0587599506063468 0.1426434016578682 0.4340987350815114 0.41707294805433903 460.74923641739053 1925914.5567516023 0.11433296926673617 0.28614288511449465 5.553061422230593e-06 5.25546752278382 -0.9161165489484786 QQS(ph)LPLRPIIPLVAR ddPTM_PC-9_AZD4547_30min_R2 1 QQSLPLRPIIPLVAR 15 1 Q9NU19 Q9NU19 TBC1D22B TBC1 domain family member 22B 1 QQS(1)LPLRPIIPLVAR 58.32 0.027917 3036600.0 5602.2 6559.6 11276.0 17582.0 12147.0 11900.0 8332.6 13159.0 9117.1 5131.9 True False 7383.583067001138 8679.862420030613 11126.47287239248 13528.741539192157 10460.59872248233 11155.891118812568 9074.185257614887 11125.578913737898 9599.01129307146 4952.233743028791 1.4909601303441973 1.752716626562542 2.2467584225108728 2.7318463225279763 2.1122990685178396 2.2526988219238646 1.8323418740863202 2.2465779062628584 1.9383195121966712 1.0 12.273863695326956 -8.62405491026706 7.6177257046094 1.0000004341000537 2.097375747262193 0.5033302609877248 0.32066429103175487 3.9917939602647916 300.7956916761962 0.3312937801116045 0.08565842271838912 2.376539788483769e-09 8.62405491026706 1.0973753131621393 QQS(ph)LPLRPIIPLVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QQSLPLRPIIPLVAR 15 1 Q9NU19 Q9NU19 TBC1D22B TBC1 domain family member 22B 1 QQS(1)LPLRPIIPLVAR 64.22399999999999 0.017165 3031800.0 6924.9 6335.6 6693.7 8512.4 7291.7 7945.2 7559.2 6403.1 5691.8 4901.4 True False 8097.148796990553 6964.556497478277 6853.303193998614 8035.477825573159 5862.943728906421 7528.5397252747725 6843.137852131314 6235.0254096452445 5775.031807172317 5789.985020538945 1.3984749128481946 1.2028626106583606 1.18364782804925 1.3878235948916493 1.012600845789526 1.3002692923329877 1.1818921513365743 1.0768638239179544 0.9974174003363421 1.0 12.499343900437543 -7.8302663047156456 1.7996720744607844 0.994843156660875 1.240659229935469 0.4881524097241452 0.10367248249893526 0.32003078527654005 1.9638246991185289 0.07839550168506536 0.02961913230374059 1.4782016927940704e-08 7.8302663047156456 0.2458160732745941 QQS(ph)LPPPK ddPTM_PC-9_AZD4547_30min_R2 5 QQSLPPPK 8 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 QQS(1)LPPPK;QQS(1)LPPPK;QQS(1)LPPPK;QQS(1)LPPPK;QQS(1)LPPPK 105.4 0.0038428000000000004 121048800.0 253317.0 257236.0 338618.0 530013.0 375930.0 297988.0 425094.0 608745.0 484869.0 392246.0 True False 333866.53667907795 340382.5064758509 334127.7040709289 407826.69146922167 323738.60852414486 279354.7632531698 462926.5424838025 514677.44781848066 510498.18546031736 378513.5869303906 0.8820463735175684 0.8992609994167736 0.8827363550687433 1.0774426745854748 0.8552892675519228 0.7380310057523606 1.2230116922300482 1.3597330864456678 1.348691838515691 1.0 18.52998556182162 -7.36073337798478 6.2758831637922174 1.2688789960196827 0.8969989262729305 0.6539941185815226 0.12155276794446845 0.14137195663368202 7.520004002471569 0.05107066193624229 0.03415177513752266 4.357793251702938e-08 7.36073337798478 -0.37188006974675214 QQS(ph)LPPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QQSLPPPK 8 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 QQS(1)LPPPK;QQS(1)LPPPK;QQS(1)LPPPK;QQS(1)LPPPK 107.83 0.0038036999999999997 75380500.0 272625.0 249481.0 194448.0 276738.0 345560.0 307768.0 361753.0 505720.0 344632.0 282625.0 True False 318775.02791080787 274247.8249175107 199084.37776814666 261233.26705670074 277849.998623216 291628.10428540065 327485.1369750853 492445.3858546327 349671.5910203108 333862.67524173117 0.9548088227592402 0.8214390084753956 0.5963061837445617 0.7824572389457924 0.8322283957679321 0.873497176868451 0.9808977201119345 1.4749938294182803 1.0473515518532681 1.0 18.348895288252415 -7.433831198083644 3.17773524004303 1.200010020468687 0.7997299856155178 0.5387240405791485 0.14820048861115528 0.1774061774856158 3.435038958139384 0.06982747947642916 0.042717133545998494 3.6827208610850465e-08 7.433831198083644 -0.4002800348531692 QQS(ph)LPPPK ddPTM_PC-9_Lapatinib_30min_R1 4 QQSLPPPK 8 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 QQS(1)LPPPK;QQS(1)LPPPK;QQS(1)LPPPK;QQS(1)LPPPK 117.52 0.0035430999999999995 84106100.0 237506.0 259586.0 220954.0 188876.0 336207.0 274374.0 333730.0 271068.0 303984.0 297061.0 True False 234119.12088673344 258984.94456591626 202788.0150271053 202766.5711118658 316431.96526839427 262639.66361703275 351008.9064465685 283662.808862386 269746.1208265689 348407.5980410985 0.6719690448860892 0.7433389685587917 0.5820424587961605 0.5819809104391209 0.9082234918168106 0.7538287485511482 1.0074662792088798 0.8141694109349614 0.7742257124792938 1.0 18.41041656087843 -6.265346321784995 24.995645768668833 0.8674602734102628 0.6473839669296579 0.6107913153692536 0.09035136840231792 241.3854837579512 1544322.5145769666 0.0275740450774328 0.03242861215128283 5.428172971395752e-07 6.265346321784995 -0.22007630648060483 QQS(ph)PQEPK ddPTM_PC-9_AZD4547_30min_R2 5 QQSPQEPK 8 0 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 QQS(1)PQEPK;QQS(1)PQEPK;QQS(1)PQEPK;QQS(1)PQEPK;QQS(1)PQEPK 96.171 0.006201600000000001 829837500.0 338326.0 352910.0 361723.0 366562.0 376241.0 418245.0 410107.0 410483.0 394145.0 396165.0 True False 445906.63038203336 466981.25596880924 356926.3166743908 282056.79422644497 324006.4315423945 392092.07403258607 446605.7285174686 347052.2843109553 414978.7000370347 382295.38393324136 1.166392923174558 1.2215194731473824 0.9336401423479374 0.7377980642206744 0.8475290185532933 1.025625970155725 1.1682216089626065 0.9078118619699568 1.085492311645334 1.0 18.544328254737998 -5.262007949985166 24.983274239379686 0.9573336909675155 1.1939562140489381 0.39103081667435924 0.11496470066785704 51.33768387578233 2255929.078573562 0.03285752240092473 0.07574159895233815 5.470059495754316e-06 5.262007949985166 0.23662252308142262 QQS(ph)PQEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 QQSPQEPK 8 0 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 QQS(1)PQEPK;QQS(1)PQEPK;QQS(1)PQEPK;QQS(1)PQEPK;QQS(1)PQEPK;QQS(1)PQEPK;QQS(1)PQEPK 115.7 0.0036225000000000003 1188396100.0 389960.0 485578.0 434072.0 461359.0 533919.0 388783.0 500861.0 439427.0 373674.0 363992.0 True False 455972.5259389204 533782.9747667956 444421.9227072262 435510.5509760594 429301.40471961204 368394.5350666445 453415.8201603793 427892.50686139136 379138.2753282453 429980.868240913 1.060448405075187 1.2414109887040918 1.0335853418906582 1.0128602994774367 0.9984197819682519 0.8567695966887474 1.054502313126955 0.9951431295348899 0.8817561508709237 1.0 18.713912943767824 -5.557898628527156 2.645425188628504 0.9694152319458237 1.1510605485115593 0.4967036199315985 0.0705521486303144 0.21209507441553907 2.975944675625923 0.019442915277440524 0.04211285363284978 2.7675875704680585e-06 5.557898628527156 0.18164531656573557 QQS(ph)PQEPK ddPTM_PC-9_Lapatinib_30min_R1 4 QQSPQEPK 8 0 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 QQS(1)PQEPK;QQS(1)PQEPK;QQS(1)PQEPK;QQS(1)PQEPK 96.756 0.0060224 824922500.0 98623.0 163923.0 153788.0 147224.0 191566.0 157972.0 177196.0 180732.0 170315.0 149105.0 True False 97216.61793475666 163543.44636489943 141144.1442788472 158051.34408486696 180298.46451324667 151215.90581071813 186370.34185331315 189129.46851460365 151132.33120354093 174877.6005800764 0.555912350193993 0.9351880733862936 0.8071024751635779 0.9037826660510206 1.0309980461487867 0.864695680345159 1.0657187726450663 1.0814962458728459 0.864217776903552 1.0 17.415985986100367 -4.199924708024948 0.7784190434907619 0.9826307634934378 7.468836676575926e-31 0.6150138431195321 0.09143901641980991 4.04121792757472 0.986664560528198 0.033681812729080794 4.26020019444867 6.310667406268772e-05 4.199924708024948 -0.9826307634934378 QQSHFAMMHGGTGFAGIDS(ph)SSPEVK ddPTM_PC-9_AZD4547_30min_R2 3 QQSHFAMMHGGTGFAGIDSSSPEVK 25 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 QQS(0.001)HFAMMHGGTGFAGIDS(0.333)S(0.333)S(0.333)PEVK;QQSHFAMMHGGTGFAGIDS(0.485)S(0.348)S(0.167)PEVK;QQSHFAMMHGGTGFAGIDS(0.409)S(0.328)S(0.264)PEVK 70.632 0.00023040000000000002 70100000.0 106748.0 87566.0 151487.0 219649.0 206474.0 185125.0 173174.0 193312.0 168079.0 202759.0 True False 140691.64350366575 115869.99705353999 149478.18340015243 169012.31659322148 177808.64910066812 173549.10448488872 188586.15051750984 163440.07226783969 176963.31279992068 195660.46912503595 0.7190601358200638 0.5921993214658695 0.7639672135541546 0.8638041059035533 0.9087612326383634 0.8869911498269124 0.9638439044986379 0.8353249534702589 0.9044408080552698 1.0 17.577992780436773 -5.648011993810629 2.2994514125042955 0.9077596821131472 0.6549446716238637 0.7989303242358863 0.051961156141125814 0.11848472040457944 1.2643002408049218 0.014350192852042884 0.02998111880298833 2.2489924950706527e-06 5.648011993810629 -0.25281501048928345 QQSHFAMMHGGTGFAGIDS(ph)SSPEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QQSHFAMMHGGTGFAGIDSSSPEVK 25 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 QQSHFAMMHGGTGFAGIDS(0.826)S(0.046)S(0.128)PEVK;QQSHFAMMHGGTGFAGIDS(0.386)S(0.307)S(0.307)PEVK 108.23 2.2416000000000002e-07 33946000.0 19657.6 19079.9 21367.0 33931.0 36680.0 42160.0 47147.0 45317.0 37033.0 29891.0 True False 22985.24342470236 20974.026377333772 21876.470314798742 32029.95607578623 29492.81730958318 39949.05538156175 42680.89484527929 44127.47676733045 37574.53756544721 35310.001682974194 0.6509556026383709 0.5939967538276002 0.6195544965195274 0.9071071806612363 0.8352539196791954 1.1313807272012797 1.208748026366116 1.2497160765814372 1.064132987101072 1.0 15.107789269409876 -6.285232655359607 1.1197883410293263 1.158683394507795 0.6072919788690463 0.837249736203872 0.09373428466785098 0.17634779279871224 0.4598150475809988 0.04023164178716079 0.05865435995783139 5.18522187632279e-07 6.285232655359607 -0.5513914156387487 QQSHFAMMHGGTGFAGIDS(ph)SSPEVK ddPTM_PC-9_Lapatinib_30min_R1 4 QQSHFAMMHGGTGFAGIDSSSPEVK 25 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 QQSHFAMMHGGTGFAGIDS(0.556)S(0.29)S(0.153)PEVK;QQSHFAMMHGGTGFAGIDS(0.777)S(0.032)S(0.191)PEVK;QQSHFAMMHGGT(0.003)GFAGIDS(0.397)S(0.3)S(0.3)PEVK;QQSHFAMMHGGTGFAGIDS(0.448)S(0.321)S(0.232)PEVK 207.73 4.4176e-31 45772700.0 85570.0 62205.7 82133.0 81212.0 92964.0 112883.0 90755.0 88056.0 124545.0 95589.0 True False 84349.75610838368 62061.666523556785 75380.34178254858 87184.60139529018 87496.04029425628 108055.25723312527 95453.84983237454 92147.40322423233 110517.43058300784 112111.43128566362 0.7523742685387516 0.5535712621973544 0.6723698102691864 0.7776602296079955 0.7804381702282748 0.9638201563745709 0.8514194202833338 0.8219269183125288 0.9857819966761978 1.0 16.77457386246708 -6.2061767591767225 1.2537298989965926 0.9111638135822661 0.6433110873155369 0.6949541534203636 0.0745318442934561 0.2577608376469976 0.8258093569253675 0.028930971718503718 0.04401803047957758 6.220470585934497e-07 6.2061767591767225 -0.2678527262667292 QQSHFAMMHGGTGFAGIDSS(ph)SPEVK ddPTM_PC-9_AZD4547_30min_R2 1 QQSHFAMMHGGTGFAGIDSSSPEVK 25 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 QQSHFAMMHGGTGFAGIDS(0.17)S(0.415)S(0.415)PEVK 58.758 0.00094335 29824000.0 30527.0 25934.0 40147.0 58988.0 51777.0 48079.0 46745.0 63228.0 46227.0 51078.0 True False 40233.95099895464 34316.65833298887 39614.6245484162 45389.227955515125 44588.6572860762 45072.61252952852 50905.21444293594 53457.56543489777 48670.46484570906 49289.77476693324 0.8162737847596369 0.6962226647464962 0.8037087760237088 0.9208649901554257 0.9046228654302789 0.9144414382628937 1.0327743367390358 1.0845569022717578 0.9874353266138345 1.0 15.58900076807795 -6.203049166956017 0.7248573890969036 1.0340304363583537 0.7352135453298329 0.8018167442300641 0.049815940563725916 0.3331458476504589 0.3703620631297618 0.030424008794429577 0.058894903382792296 6.265429290428712e-07 6.203049166956017 -0.2988168910285208 QQSHFAMMHGGTGFAGIDSS(ph)SPEVK ddPTM_PC-9_Lapatinib_30min_R1 3 QQSHFAMMHGGTGFAGIDSSSPEVK 25 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 QQSHFAMMHGGT(0.001)GFAGIDS(0.102)S(0.449)S(0.449)PEVK;QQS(0.001)HFAMMHGGT(0.004)GFAGIDS(0.168)S(0.413)S(0.413)PEVK;QQSHFAMMHGGT(0.016)GFAGIDS(0.27)S(0.357)S(0.357)PEVK 57.238 0.0044215 47051400.0 98853.0 71853.0 102461.0 87373.0 115390.0 127496.0 107253.0 104667.0 144577.0 108246.0 True False 97443.33809258012 71686.62879313533 94037.05209089782 93798.70188778348 108602.98706546862 122043.29328769205 112806.03554704068 109530.2109256695 128293.21579669627 126956.17687127164 0.767535227461864 0.5646564866695901 0.7407048196343179 0.7388273985510095 0.8554368108893795 0.9613025241886336 0.8885431046133452 0.8627403063399478 1.0105314995959616 1.0 16.953971063394377 -6.238200994897985 1.4633206599041435 0.9362573791560224 0.6715694271320782 0.7543493375860902 0.06531407196988584 0.1953068764537553 0.8376560802734349 0.02369879560558965 0.033403389460340965 5.778285619154995e-07 6.238200994897985 -0.26468795202394413 QQSHFAMMHGGTGFAGIDSSS(ph)PEVK ddPTM_PC-9_AZD4547_30min_R2 4 QQSHFAMMHGGTGFAGIDSSSPEVK 25 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 QQSHFAMMHGGTGFAGIDS(0.057)S(0.043)S(0.9)PEVK;QQSHFAMMHGGTGFAGIDS(0.283)S(0.181)S(0.536)PEVK;QQSHFAMMHGGTGFAGIDS(0.262)S(0.181)S(0.557)PEVK;QQSHFAMMHGGT(0.005)GFAGIDS(0.227)S(0.182)S(0.586)PEVK 138.42 1.6433e-07 60143900.0 112859.0 91020.0 154977.0 222789.0 214208.0 197297.0 185606.0 209979.0 160796.0 215638.0 True False 148745.81438696958 120440.43500688844 152921.90371982695 171428.43810573773 184468.9166992259 184959.9874007025 202124.574433534 177531.5703873976 169295.34828846008 208088.57925509856 0.714819693226028 0.5787940666327435 0.7348884992499177 0.8238243478782241 0.8864922686270206 0.8888521804647317 0.9713391054765518 0.8531538396913138 0.8135734738277907 1.0 17.666838260729776 -5.762054488370713 1.875820240338124 0.8977587924344135 0.6448181239993789 0.7458101463917269 0.06001039402722623 0.16466962626169987 1.1813700021155682 0.0183014142149608 0.037132891172032376 1.7295993429590392e-06 5.762054488370713 -0.2529406684350346 QQSHFAMMHGGTGFAGIDSSS(ph)PEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QQSHFAMMHGGTGFAGIDSSSPEVK 25 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 QQSHFAMMHGGTGFAGIDS(0.129)S(0.095)S(0.776)PEVK;QQSHFAMMHGGT(0.024)GFAGIDS(0.086)S(0.069)S(0.822)PEVK 83.22 0.00021758 7824600.0 21430.4 19287.3 23141.0 36039.0 39394.0 43959.0 43386.0 45886.0 38387.0 37656.0 True False 25058.143450306332 21202.015678674932 23692.769202731222 34019.85167001446 31675.028492195168 41653.712654603245 39276.1639925613 44681.541120235794 38948.33725393085 44482.73471526802 0.5633229074314423 0.4766347171411128 0.5326284311067556 0.7647877741279622 0.712074666608193 0.9364017954657414 0.8829529983704071 1.0044692936763067 0.8755832460220218 1.0 15.440957864528052 -6.209693443585467 0.8897234288007567 0.9555493988303871 0.4884353632581303 0.8845289967832703 0.06336703090347132 0.18175145779213786 0.3051513898046614 0.029779085320424493 0.05186573055404409 6.170303927977246e-07 6.209693443585467 -0.46711403557225684 QQSHFAMMHGGTGFAGIDSSS(ph)PEVK ddPTM_PC-9_Lapatinib_30min_R1 3 QQSHFAMMHGGTGFAGIDSSSPEVK 25 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 QQS(0.001)HFAMMHGGT(0.001)GFAGIDS(0.228)S(0.228)S(0.542)PEVK;QQSHFAMMHGGT(0.001)GFAGIDS(0.185)S(0.185)S(0.628)PEVK;QQSHFAMMHGGTGFAGIDS(0.294)S(0.202)S(0.504)PEVK 85.366 5.7986e-06 52813600.0 166192.0 100245.0 166703.0 147468.0 175489.0 196047.0 149295.0 177414.0 251341.0 188248.0 True False 163822.07160411964 100012.88886153462 152997.32283218898 158313.2886588266 165167.08204464873 187662.5268178783 157024.76459395466 185657.3021216495 223032.32984193476 220786.41597530662 0.7419934368717773 0.45298479265463665 0.6929652902617914 0.7170427037346936 0.7480853444494587 0.8499731561332424 0.7112066378735763 0.8408909637919659 1.010172337173494 1.0 17.75229188655323 -7.151909158676907 0.36038780699171447 1.0263286159133544 0.5591683610966987 0.6589429390549018 0.08962770749401616 0.9028295240919374 0.2801642020503081 0.10732147782554173 0.15230491437288093 7.048404849462235e-08 7.151909158676907 -0.4671602548166558 QQSLPSLCSTSDPDTPLGAPSTPGRIS(ph)LR ddPTM_PC-9_AZD4547_30min_R2 1 QQSLPSLCSTSDPDTPLGAPSTPGRISLR 29 1 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 QQSLPSLCSTSDPDT(0.009)PLGAPS(0.152)T(0.152)PGRIS(0.687)LR 70.718 4.0359e-05 3490200.0 4326.1 2149.4 2052.1 5213.4 5706.0 3704.4 4235.0 5459.5 3458.6 3582.5 True False 5701.709811530048 2844.1515161921157 2024.887813181678 4011.5311762270735 4913.820392729414 3472.7632823974163 4611.906795717904 4615.859721829322 3641.41453512816 3457.077765428134 1.6492859572176652 0.8227039451164582 0.5857223790078411 1.1603821054717507 1.4213797681582883 1.004537218435218 1.334047744554208 1.33519117446225 1.0533215571669956 1.0 11.755337341411273 -5.978671586897004 24.993035739925862 1.2136805950329466 0.9784954455783234 0.05986322112246589 0.2856587075092259 517.1671767751535 606021.8381618907 0.08024586057552346 0.11901283491526603 1.0503363918676469e-06 5.978671586897004 -0.2351851494546232 QQSLPSLCSTSDPDTPLGAPSTPGRIS(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 1 QQSLPSLCSTSDPDTPLGAPSTPGRISLR 29 1 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 QQSLPSLCSTSDPDTPLGAPSTPGRIS(0.999)LR 81.455 5.9162e-05 0.0 3762.4 2974.1 3694.5 3413.4 5188.3 6844.5 5090.4 4334.1 5092.1 4564.4 True False 3708.7474860603443 2967.21365417816 3390.7524711824162 3664.432822768599 4883.134394590266 6551.776690308789 5353.956004481506 4535.478108409939 4518.574075809822 5353.350458319301 0.6927899667575128 0.5542722594533303 0.6333888464023617 0.6845120362097605 0.9121641545065854 1.2238647070316666 1.000113115359609 0.8472223411717126 0.8440646864035949 1.0 12.386226386769351 -6.260038938729367 3.394947528146474 0.9825070337417825 0.6264118386535982 0.7120808021206051 0.10377464497780958 0.14429667935865834 3.5387174068203664 0.036152799056405026 0.04484853627080365 5.494916043757523e-07 6.260038938729367 -0.3560951950881843 QQSNEHLR ddPTM_PC-9_AZD4547_30min_R2 3 QQSNEHLR 8 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ;; 163.15 1.8435e-08 4485900.0 24306.0 19136.7 30402.699999999997 24195.300000000003 24020.2 24173.199999999997 19335.899999999998 28906.4 41557.0 51921.5 False True 32034.802403793077 25322.264036435125 29999.540333228728 18617.44739865863 20685.409848832645 22661.645982628568 21056.757641398308 24439.580082990597 43753.61817970301 50103.74408867461 0.6393694320946802 0.5053966424469052 0.5987484743682017 0.3715779676207251 0.4128515787607248 0.4522944621168736 0.42026315646454754 0.48777951683085674 0.8732604513999388 1.0 15.612630794872874 -8.34076958273534 3.336716310192046 0.9916302100614234 0.47891024306177493 0.8424371468186309 0.07873101744034029 0.09072395064608094 1.840635713461287 0.07869132807441505 0.021380005082590046 4.562789329768902e-09 8.34076958273534 -0.5127199669996485 QQSNEHLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QQSNEHLR 8 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ;;; 162.97 1.7374e-05 6579900.0 15729.8 30851.1 32754.300000000003 23394.0 79232.0 50403.6 24917.8 42387.7 62871.0 62276.0 False True 18392.544462288544 33913.793320183126 33535.2867333745 22083.31002437131 63707.058371670995 47760.34648553335 22557.40559475048 41275.06778848056 63790.3694347536 73566.14582345511 0.2500137020420668 0.4609972826572951 0.4558521634917897 0.3001830499230868 0.8659833631159084 0.6492163746099896 0.3066275301262078 0.5610606254612407 0.8671158278134955 1.0 16.166754389188483 -10.450896706334127 0.09827160624965783 1.776865655865672 1.9726846641657373e-15 0.5236804506965835 0.17413068244558852 49.72389624524027 0.9997731539800684 14.466334701149037 4.843709936481798 3.540815466936236e-11 10.450896706334127 -1.77686565586567 QQSNEHLR ddPTM_PC-9_Lapatinib_30min_R1 1 QQSNEHLR 8 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 168.26 0.00048127 1214200.0 1922.5 3514.1 3206.2 4320.6 5252.4 3527.5 8110.8 10631.0 9169.7 4543.5 False True 1895.0847974566782 3505.963317355661 2942.598612289906 4638.351337099086 4943.464158615715 3376.6370480041255 8530.73753755081 11124.955070373575 8136.911824778247 5328.837921166801 0.35562815486077515 0.6579226783065671 0.5522026858053877 0.8704245476626307 0.9276814629658122 0.6336535466000396 1.6008626390503773 2.087688767223316 1.526958024461099 1.0 12.379605238254522 -7.2718058646738015 8.463969595583398 1.645884898385298 0.6815165576379681 0.6857354330554581 0.2916287568736024 0.09226633431924461 56.2519064792463 0.11726495141813639 0.08248364168372956 5.348033700892365e-08 7.2718058646738015 -0.9643683407473299 QQSNEHLRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QQSNEHLRR 9 1 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ;; 83.647 0.008867299999999998 1289730.0 0.0 1007.3199999999999 1333.6299999999999 1870.51 5012.52 4368.79 532.33 1866.5 3741.0 4700.799999999999 False True 0.0 1107.3200724540409 1365.4287970199405 1765.711388975242 4030.3526886758955 4139.682961584753 481.90384866454986 1817.5063527202226 3795.705047723329 5553.017828487673 0.0 0.1994087011162383 0.2458895035443828 0.31797329731536655 0.7257950205021285 0.7454834631266019 0.08678233413772293 0.327300651439689 0.6835391430315403 1.0 12.439056312507715 -11.020711258127484 0.1325532588396285 1.8060688372095084 2.0300011017114196e-14 0.5116456374633592 0.21976502356777572 42.444435717620884 0.9540643455701651 13.737473447699337 2.336131358247773 9.534298437842673e-12 11.020711258127484 -1.8060688372094882 QQSSSSRES(ph)PVPK ddPTM_PC-9_Lapatinib_30min_R1 1 QQSSSSRESPVPK 13 1 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 QQS(0.025)S(0.012)S(0.038)S(0.019)RES(0.906)PVPK 112.02 0.0024193 2426600.0 8392.9 7978.6 6657.9 10110.0 7595.5 8340.2 4512.3 6638.6 6131.6 6145.7 True False 8273.215706930641 7960.126041903721 6110.513162237221 10853.523125971327 7148.747623327555 7983.509087955777 4745.924815146535 6947.05359140081 5440.994639389543 7207.9760563695 1.1477862360016884 1.1043496786964997 0.8477432658558182 1.5057657019241002 0.9917829314943954 1.107593730267869 0.6584268285620463 0.9638008696299539 0.7548574796640006 1.0 12.815378503441957 -7.182464371790883 9.723641253604479 0.8414331383090713 1.117012250598827 0.3577700429511127 0.1793325801458378 0.5364333340023028 63.42436470141326 0.06629204633266916 0.05133380334284705 6.569550088726793e-08 7.182464371790883 0.2755791122897556 QQSTPQAANS(ph)PPNLGAK ddPTM_PC-9_AZD4547_30min_R2 1 QQSTPQAANSPPNLGAK 17 0 Q9Y4C1;F8WE62 Q9Y4C1 KDM3A Lysine-specific demethylase 3A 1 QQSTPQAANS(1)PPNLGAK 143.83 2.108e-08 0.0 10705.0 10534.0 13147.0 17176.0 18035.0 16382.0 12026.0 19019.0 13272.0 16160.0 True False 14108.967322167571 13938.909496402597 12972.662189902803 13216.338566554685 15531.15155676042 15357.630950284654 13096.290702551021 16080.05056314166 13973.530824674994 15594.243318721186 0.9047548530443594 0.8938496861639109 0.8318878912405372 0.8475139380881802 0.9959541632978739 0.9848269413526161 0.8398157214097509 1.0311529860405124 0.8960698213487219 1.0 13.928725929900923 -6.25320397957023 24.7992516224969 0.9549627278955314 0.8685540459101617 0.3775708862692234 0.05556091444043708 619.4073341068679 1865219.9959149165 0.01620715331121616 0.020552011801036902 5.582079538678558e-07 6.25320397957023 -0.08640868198536966 QQSTPQAANS(ph)PPNLGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QQSTPQAANSPPNLGAK 17 0 Q9Y4C1;F8WE62 Q9Y4C1 KDM3A Lysine-specific demethylase 3A 1 QQSTPQAANS(1)PPNLGAK 156.13 3.7346e-17 0.0 6999.6 8863.1 7707.8 9527.3 10683.0 8802.3 9511.9 8319.4 7757.6 7931.5 True False 8184.494031598294 9742.969993812705 7891.583183994284 8993.516268923346 8589.742838557175 8340.691892436449 8610.863971807577 8101.024565132933 7871.040224062676 9369.418164280543 0.8735327944696086 1.039869266477642 0.8422703572010185 0.9598799104953747 0.9167850861117759 0.8902038254876964 0.9190393491705988 0.8646240805023343 0.840077802703886 1.0 13.193743744758926 -6.581625539334826 4.90218737289365 0.8956374903284834 0.9315243990939005 0.03009461578428463 0.06277111211482424 0.6032716510986982 29.717425142943718 0.019964982674994667 0.02014329844904576 2.6204414512339114e-07 6.581625539334826 0.035886908765417114 QQSTPQAANS(ph)PPNLGAK ddPTM_PC-9_Lapatinib_30min_R1 1 QQSTPQAANSPPNLGAK 17 0 Q9Y4C1;F8WE62 Q9Y4C1 KDM3A Lysine-specific demethylase 3A 1 QQSTPQAANS(1)PPNLGAK 164.56 2.7281e-18 0.0 19375.0 18850.0 17262.0 16748.0 18140.0 16074.0 15647.0 16151.0 18152.0 15619.0 True False 19098.708947060164 18806.353983140547 15842.78499324695 17979.7037896902 17073.040864612176 15386.552490324115 16457.125098641016 16901.434422124315 16107.530610965976 18318.723338990705 1.0425786007919717 1.0266192482481538 0.864841108196999 0.9814932764130503 0.9319994930144972 0.8399358517290572 0.8983772937720311 0.922631676310666 0.8792932953292498 1.0 14.161031342772208 -5.2039848419704136 7.8574292973594595 0.9118431308032682 1.0357513898055934 0.5112121569534156 0.04678301772991137 0.24132414772983538 29.79863756690105 0.011690464760062075 0.0311525896374059 6.251945133420205e-06 5.2039848419704136 0.12390825900232527 QQTEKPES(ph)EDEWER ddPTM_PC-9_AZD4547_30min_R2 3 QQTEKPESEDEWER 14 1 A2AB15;A0A140T947;O60231 A2AB15 DHX16 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 1 QQTEKPES(1)EDEWER;QQT(0.006)EKPES(0.994)EDEWER;QQTEKPES(1)EDEWER 140.46 0.00057352 241111000.0 110253.0 100259.0 97631.0 86903.0 110344.0 96759.0 122122.0 109254.0 100490.0 106328.0 True False 145311.16059513687 132665.76107839646 96336.34914903773 66868.8559879658 95024.64027608371 90708.64443404903 132990.6214183385 92371.30470716016 105801.69624559903 102605.48908372462 1.416212347826392 1.292969433342334 0.938900540403142 0.6517083694557683 0.9261165374743738 0.8840525516138037 1.2961355440723064 0.9002569505008303 1.031150450043334 1.0 16.64674838727302 -5.181175213309779 3.8813754044062208 0.9474534991460856 1.3856704942777247 0.5351074236003471 0.15096515600454244 0.1836991675188873 5.190089149208244 0.04176793113452611 0.1257074113616767 6.589080094231012e-06 5.181175213309779 0.43821699513163914 QQTEKPES(ph)EDEWER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QQTEKPESEDEWER 14 1 A2AB15;A0A140T947;O60231 A2AB15 DHX16 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 1 QQTEKPES(1)EDEWER;QQT(0.006)EKPES(0.994)EDEWER 176.28 0.00050297 55763000.0 46511.0 52640.0 47433.0 55349.0 64506.0 44332.0 59451.0 44731.0 47333.0 42915.0 True False 54384.39366587641 57865.75131435957 48563.98261065425 52247.974973879114 51866.512360195506 42007.15187797428 53819.3708920334 43556.85864641211 48025.15557976161 50695.14978504693 1.0727731133347524 1.1414455142102704 0.9579611228405663 1.0306306460364816 1.0231060087624808 0.8286226997274743 1.0616276136915173 0.8591918325736887 0.9473323539508929 1.0 15.6295601047705 -5.4976883632370095 0.8070127886878099 0.9413312867810937 1.131266002376756 0.3462770110905419 0.07397661980478171 1.172366069765146 1.1329176352684 0.03083573537191597 0.16731380142579655 3.179154518793408e-06 5.4976883632370095 0.18993471559566233 QQTEKPES(ph)EDEWER ddPTM_PC-9_Lapatinib_30min_R1 4 QQTEKPESEDEWER 14 1 A2AB15;A0A140T947;O60231 A2AB15 DHX16 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 1 QQT(0.048)EKPES(0.952)EDEWER;QQTEKPES(1)EDEWER;QQT(0.001)EKPES(0.999)EDEWER;QQTEKPES(1)EDEWER 125.39 0.00016971 354994400.0 380625.0 336732.0 345459.0 334015.0 398351.0 317988.0 390647.0 356818.0 340120.0 324803.0 True False 375197.21770192357 335952.3177427523 317056.6945303039 358579.5773413765 374920.77736819885 304388.3945062328 410872.7902095487 373397.0669081512 301812.10397761984 380944.7657772064 0.9849123847034448 0.8818924629594 0.8322904604908862 0.9412902067568766 0.9841867143213863 0.7990355081666952 1.078562634588988 0.9801868944080218 0.7922726103398756 1.0 18.539222307021582 -7.254229857012208 24.995884960569075 0.9611044429730268 0.9050219652797014 0.09924688808478788 0.08671823527558412 1516.088007225803 5256390.826175512 0.033636081106683126 0.025526137222265988 5.5689092785891256e-08 7.254229857012208 -0.05608247769332542 QQTNQHNYR ddPTM_PC-9_Lapatinib_30min_R1 2 QQTNQHNYR 9 0 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 0 ; 100.48 0.0023888 153050.0 549.97 1915.09 616.82 1595.29 1771.6 526.97 2046.87 3255.8 1521.13 1666.49 False True 542.1273269478539 1910.6557267677777 566.1074405940556 1712.6129483314335 1667.3979710996118 504.4327215270686 2152.846913188171 3407.0763538822584 1349.804321190981 1954.5405760416556 0.2773681619062484 0.9775472303763815 0.2896370878830968 0.8762227652494301 0.8530894633440835 0.2580825016939009 1.1014593094547704 1.7431596947361845 0.6905992834001997 1.0 10.932613819786319 -7.4255780883381375 7.247773800780268 1.2128154136783917 0.6197369163604872 0.3655361702980252 0.3471442780460197 0.26142735465140726 16.948063755217085 0.13839730737143585 0.09267366336004568 3.7533746083600804e-08 7.4255780883381375 -0.5930784973179045 QQTQQVQSPVDSATMS(ph)PVER ddPTM_PC-9_AZD4547_30min_R2 2 QQTQQVQSPVDSATMSPVER 20 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 QQTQQVQSPVDS(0.001)AT(0.006)MS(0.993)PVER;QQTQQVQSPVDS(0.001)AT(0.243)MS(0.756)PVER 143.72 0.00019689 22255000.0 19072.7 18333.8 27676.0 38576.0 26054.0 29314.0 23139.4 34361.0 26989.0 26765.2 True False 25137.421863195286 24259.842313000372 27308.998156822847 29682.899193258836 22436.851824776066 27480.9909459556 25198.7617730425 29051.296987229103 28415.58344086447 25828.15849469283 0.9732564506432204 0.9392788230715435 1.0573343106297841 1.1492456653213614 0.8686973107039896 1.0639934299459404 0.9756313745023805 1.124791649129711 1.1001784523934721 1.0 14.656657164883704 -7.757028386697236 24.999891078525504 1.0843637902912955 1.006186984686088 0.14490902105151615 0.07798934192352437 197.62004649471177 1120058.2622833336 0.038025117080088815 0.02099990507496993 1.7497323175080474e-08 7.757028386697236 -0.07817680560520746 QQTQQVQSPVDSATMS(ph)PVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QQTQQVQSPVDSATMSPVER 20 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 QQTQQVQSPVDS(0.251)AT(0.006)MS(0.743)PVER 104.55 0.00013778 6214400.0 7086.1 7144.2 7077.7 10285.0 14864.0 21119.0 25865.0 21025.0 23291.0 19141.0 True False 8285.636773145427 7853.428961627044 7246.459210326723 9708.76479441989 11951.505902116802 20011.482462125292 23414.87995361634 20473.11602782891 23631.58681275703 22611.111779927367 0.36644092753107615 0.34732608630942213 0.32048221603856053 0.4293802484775951 0.5285678129602875 0.8850286822203121 1.0355474857455926 0.9054449081094532 1.0451315725985473 1.0 14.464744310159638 -6.692250031483063 1.9210876497402607 0.9949674267979657 0.35637957293359906 0.9788036665880917 0.04315404984195571 0.042792277632795576 0.325054846753144 0.017027776022529185 0.016393471860591674 2.0311872816163342e-07 6.692250031483063 -0.6385878538643666 down QQTQQVQSPVDSATMS(ph)PVER ddPTM_PC-9_Lapatinib_30min_R1 2 QQTQQVQSPVDSATMSPVER 20 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 QQTQQVQSPVDSAT(0.004)MS(0.996)PVER;QQTQQVQSPVDSAT(0.004)MS(0.995)PVER 210.98 1.0187000000000002e-21 10405700.0 27667.1 21939.9 27680.8 22987.6 46208.0 55914.0 57949.0 59882.0 68330.0 56092.0 True False 27272.562080475258 21889.099509533444 25404.991474978007 24678.184788385603 43490.136288423346 53522.68856190015 60949.31567336532 62664.336329988706 60633.9558532011 65787.42746210803 0.4145558373776448 0.33272466113895455 0.38616788123552437 0.37512007598411784 0.6610706325835984 0.8135701702689002 0.92645841347833 0.9525275382759396 0.9216647951179547 1.0 16.005524278538033 -6.588368540376093 1.4725036808250536 0.9490424835627913 0.36043936350494565 0.9821075020172814 0.034992164843292546 0.04482506188087119 0.20069109833477164 0.014136138773773038 0.014811304545432252 2.5800698255588324e-07 6.588368540376093 -0.5886031200578457 down QQVAFYGQTLGQAQAHS(ph)QEQ ddPTM_PC-9_AZD4547_30min_R2 3 QQVAFYGQTLGQAQAHSQEQ 20 0 Q96I24;Q96I24-2 Q96I24 FUBP3 Far upstream element-binding protein 3 1 QQVAFYGQTLGQAQAHS(1)QEQ;QQVAFYGQTLGQAQAHS(1)QEQ;QQVAFYGQTLGQAQAHS(1)QEQ 210.71 1.3181e-21 16011800.0 57764.0 54613.0 74120.0 105660.0 94752.0 78829.0 74504.0 103633.0 68629.0 80388.0 True False 76131.75043416052 72265.584234577 73137.1203708524 81301.71943072711 81597.32033857287 73899.8101684771 81134.71166662722 87618.90109942983 72256.5888311196 77573.64058820283 0.9814126274967996 0.9315739687685477 0.9428089208691189 1.0480585778140112 1.0518691622548646 0.9526407373449424 1.045905684603978 1.12949322005592 0.9314580092314008 1.0 16.24327888952655 -5.755303246593201 24.990986251734085 1.0274243757085537 0.9498960317820911 0.2654159334398508 0.05358766947427213 182.3747775684767 742758.7190499551 0.0144707659719023 0.024274250477222176 1.756696570330017e-06 5.755303246593201 -0.07752834392646257 QQVAFYGQTLGQAQAHS(ph)QEQ ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QQVAFYGQTLGQAQAHSQEQ 20 0 Q96I24;Q96I24-2 Q96I24 FUBP3 Far upstream element-binding protein 3 1 QQVAFYGQTLGQAQAHS(1)QEQ;QQVAFYGQTLGQAQAHS(1)QEQ;QQVAFYGQTLGQAQAHS(1)QEQ 236.66 1.3775999999999997e-118 10528600.0 90535.0 81861.0 104211.0 108993.0 115103.0 99841.0 102020.0 99429.0 89664.0 79320.0 True False 105860.78735224158 89987.61907949824 106695.78546241835 102886.47557007373 92549.39342379906 94605.16219996466 92355.92703916265 96819.09410373356 90975.16637237751 93700.08810322527 1.1297832210746632 0.9603792365740663 1.1386946119503782 1.0980403290200562 0.9877193852992056 1.0096592662297426 0.9856546446084254 1.0332871191868274 0.9709186854995715 1.0 16.515762783955005 -6.26555441981445 24.910280149548633 0.9995159146258008 1.0771261469350701 0.42148012337203455 0.04798270473273556 357.3178782883509 2163011.623927972 0.014342620274545692 0.016840591225269548 5.425572612515875e-07 6.26555441981445 0.07761023230926933 QQVAFYGQTLGQAQAHS(ph)QEQ ddPTM_PC-9_Lapatinib_30min_R1 4 QQVAFYGQTLGQAQAHSQEQ 20 0 Q96I24;Q96I24-2 Q96I24 FUBP3 Far upstream element-binding protein 3 1 QQVAFYGQTLGQAQAHS(1)QEQ;QQVAFYGQTLGQAQAHS(1)QEQ;QQVAFYGQTLGQAQAHS(1)QEQ;QQVAFYGQTLGQAQAHS(1)QEQ 145.71 1.3449000000000001e-05 20149000.0 159575.0 128976.0 154161.0 128698.0 134848.0 145958.0 118477.0 125958.0 154274.0 106819.0 True False 157299.43123752903 128677.36399626193 141486.4776586688 138162.88024394267 126916.50576136853 139715.7165847162 124611.15934758676 131810.46851228594 136898.03754275912 125282.52182262919 1.2555576703686433 1.0270974923256977 1.1293393172511377 1.1028104976969497 1.0130423934238224 1.1152051742901619 0.9946412119960921 1.0521058053005894 1.0927145746361555 1.0 16.934825632602923 -4.7550701887342965 24.971142380331003 1.0621254278338799 1.255557997015503 0.6119599078324276 0.046985454276955635 141.98922879357843 556632.0913916422 0.011323562479706471 0.10390037434247161 1.7576395291532213e-05 4.7550701887342965 0.19343256918162322 QQVEQSSAS(ph)QTGIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QQVEQSSASQTGIK 14 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 QQVEQS(0.006)S(0.023)AS(0.863)QT(0.109)GIK 153.79 9.470000000000001e-09 0.0 6666.0 6028.3 7668.8 9451.5 11600.0 11236.0 11889.0 10245.0 9191.6 10096.0 True False 7794.422140498635 6626.7497843532265 7851.653276085955 8921.963097176433 9327.063271296745 10646.764380152454 10762.787851093935 9976.079605474779 9326.009761201209 11926.324880107977 0.6535476954429625 0.5556405557428711 0.6583464189527318 0.748089892474542 0.782056783213531 0.8927112490378563 0.9024395997332996 0.8364755870531391 0.7819684483655265 1.0 13.541861921821347 -6.036836604791644 1.2519112363850837 0.87333629893257 0.5988387545906296 0.7794649176893681 0.05966569732919596 0.21120434850102282 0.6732455238876255 0.022236938586840463 0.040459733657286286 9.186781670185757e-07 6.036836604791644 -0.2744975443419404 QQVEQSSAS(ph)QTGIK ddPTM_PC-9_Lapatinib_30min_R1 1 QQVEQSSASQTGIK 14 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 QQVEQS(0.001)S(0.001)AS(0.541)QT(0.457)GIK 203.05 1.2694e-10 6138000.0 17179.0 14045.0 17317.0 14890.0 15713.0 15365.0 10719.0 11115.0 15739.0 23510.0 True False 16934.02430975724 14012.479665422232 15893.263105553091 15985.060271583887 14788.7922329466 14707.8747675644 11273.977371530202 11631.443477302431 13966.30808098247 27573.672174894135 0.6141374352443231 0.5081832980585231 0.5763926909968825 0.5797218509813976 0.5363374214048942 0.5334028298543398 0.4088674624120313 0.42183149939284753 0.5065088172658705 1.0 14.751003793278377 -10.934708407121859 6.361507550757754 1.0000873286622913 0.5182613814689769 0.8433541143672206 0.061976047825793884 8.514163978726905e-05 7.871979338768733e-06 0.06655861895431106 0.016139936991796083 1.1622286925155413e-11 10.934708407121859 -0.4818259471933144 QQVSWEQEFLVGS(ph)SPGGSGR ddPTM_PC-9_AZD4547_30min_R2 1 QQVSWEQEFLVGSSPGGSGR 20 0 Q9BUA3 Q9BUA3 C11orf84 Uncharacterized protein C11orf84 1 QQVSWEQEFLVGS(0.893)S(0.107)PGGSGR 206.8 3.6594999999999995e-21 5504200.0 31261.0 30690.0 42247.0 45208.0 46846.0 38995.0 42047.0 57997.0 38543.0 39406.0 True False 41201.347730806214 40609.9423243398 41686.777176300595 34785.99405663743 40342.241520820586 36556.63648555431 45789.101544167876 49034.89628847605 40580.304292905996 38026.4079342529 1.0834930241647525 1.0679405321310862 1.0962586118672166 0.9147851702633049 1.060900666467675 0.9613486645585929 1.2041395449009162 1.2894958780554993 1.0671611255806424 1.0 15.214714044518576 -7.2695560570293285 24.928934291288826 1.164323796594113 1.031548408049634 0.24504807832652697 0.09018286993892319 703.8883260383204 2161858.0471919375 0.03656518699787631 0.02512209042436581 5.3758103979049445e-08 7.2695560570293285 -0.1327753885444789 QQVSWEQEFLVGS(ph)SPGGSGR ddPTM_PC-9_Lapatinib_30min_R1 1 QQVSWEQEFLVGSSPGGSGR 20 0 Q9BUA3 Q9BUA3 C11orf84 Uncharacterized protein C11orf84 1 QQVSWEQEFLVGS(0.5)S(0.5)PGGSGR 260.11 1.4053999999999997e-66 3634500.0 11449.0 15953.0 17377.0 13182.0 15038.0 17657.0 15713.0 15072.0 15461.0 13867.0 True False 11285.735160510547 15916.061808649389 15948.330137159784 14151.44825386291 14153.49440584554 16901.851270477346 16526.542255700533 15772.300143041155 13719.619368452248 16263.892473383952 0.6939135375482703 0.9786133199476207 0.9805973670361761 0.8701144745651707 0.8702402840530271 1.0392254682043318 1.016149257180986 0.9697740051376205 0.8435630886581772 1.0 13.989384961685083 -6.740663722314223 24.97558907039655 0.9745036888325589 0.8894312121016827 0.21791921855467788 0.08886757310465951 435.62311008094025 523685.97505053773 0.029803272518869005 0.02977195257183287 1.8169219754395133e-07 6.740663722314223 -0.08507247673087615 QQVSWEQEFLVGSS(ph)PGGSGR ddPTM_PC-9_AZD4547_30min_R2 1 QQVSWEQEFLVGSSPGGSGR 20 0 Q9BUA3 Q9BUA3 C11orf84 Uncharacterized protein C11orf84 1 QQVSWEQEFLVGS(0.033)S(0.967)PGGSGR 291.57 1.2259999999999996e-107 5772100.0 30501.0 33380.0 43408.0 55074.0 46801.0 46802.0 41175.0 55547.0 35790.0 42925.0 True False 40199.68353978824 44169.432218522714 42832.38155771665 42377.54018481793 40303.48899406404 43875.463541400466 44839.4952334557 46963.487493076915 37681.786333266886 41422.20881535312 0.9704862364772843 1.066322474868876 1.0340438808719647 1.0230632647747824 0.9729922702510633 1.0592255892722469 1.0824988940917115 1.1337755478570695 0.9097000717957887 1.0 15.338116866038623 QQVSWEQEFLVGSS(ph)PGGSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QQVSWEQEFLVGSSPGGSGR 20 0 Q9BUA3 Q9BUA3 C11orf84 Uncharacterized protein C11orf84 1 QQVSWEQEFLVGS(0.039)S(0.961)PGGSGR;QQVSWEQEFLVGS(0.25)S(0.711)PGGS(0.04)GR 204.05 3.245199999999999e-60 3261000.0 12692.2 15927.9 15285.900000000001 12225.4 17974.1 17606.3 12930.2 16956.4 9279.4 11400.8 True False 14840.738777623274 17509.116648176067 15650.37382809858 11540.450473281568 14452.204133156456 16682.994633880237 11705.35784945873 16511.312466790885 9415.093670099932 13467.674791316862 1.101952564758371 1.3000846040227285 1.1620694790008583 0.8568999958866061 1.0731031419376387 1.238743501932228 0.8691446764816175 1.225995780462146 0.6990882847995566 1.0 13.717213168983344 -4.979637905425671 0.3014488266665811 0.9473791324560599 1.3785787327861734 0.171175042810795 0.1679913630299268 12.847264555039652 1.0504496840456607 0.19186799404089291 2.029857963940306 1.048001959269413e-05 4.979637905425671 0.4311996003301135 QQVSWEQEFLVGSS(ph)PGGSGR ddPTM_PC-9_Lapatinib_30min_R1 1 QQVSWEQEFLVGSSPGGSGR 20 0 Q9BUA3 Q9BUA3 C11orf84 Uncharacterized protein C11orf84 1 QQVSWEQEFLVGS(0.106)S(0.892)PGGS(0.002)GR 231.5 1.3616999999999998e-36 3808600.0 21163.0 19589.0 27912.0 23365.0 26170.0 26580.0 21473.0 22881.0 30296.0 21057.0 True False 20861.211739181115 19543.64287404458 25617.1831034358 25083.34004335512 24630.732052199604 25443.2353610063 22584.76687180407 23944.134791197223 26883.745448976726 24696.674393311165 0.8446972012082387 0.7913471491261905 1.0372725774922127 1.0156565877610098 0.9973299100898613 1.0302292104518063 0.9144861576148454 0.9695287069777395 1.0885573102205983 1.0 14.59202916389798 -5.260028415555239 24.99998578044957 1.0030861434285472 0.8180221611164588 0.7414707665325649 0.04450913710388617 59.953085583940435 1062243.6189402684 0.011698400781788583 0.027733346458971343 5.49504918995512e-06 5.260028415555239 -0.18506398231208843 QQWSNGY(ph)LAVQK ddPTM_PC-9_Lapatinib_30min_R1 1 QQWSNGYLAVQK 12 0 D6RB29 D6RB29 ALPK1 1 QQWS(0.2)NGY(0.8)LAVQK 78.655 0.042839999999999996 0.0 9436.2 9188.8 9629.3 7875.7 10646.0 8761.1 8750.9 6854.7 8288.8 8161.5 True False 9301.638057612852 9167.523898158186 8837.61612417291 8454.905250565027 10019.823210841303 8386.408176121598 9203.978783517452 7173.194386312645 7355.228059066484 9572.204400484838 0.9717341657624569 0.957723374324711 0.9232581915744799 0.8832767142056412 1.046762353960368 0.8761208834713999 0.961531784993148 0.7493774773498693 0.7683943793233184 1.0 13.224635488519 -7.745909972171275 24.99760363857158 0.8191644386876535 0.9441678611173643 0.27129108500374854 0.07790729398926811 244.00239697828283 392770.5846562588 0.034927418519966315 0.020073903566507345 1.7951057078202887e-08 7.745909972171275 0.12500342242971074 QQYESVAAK ddPTM_PC-9_Lapatinib_30min_R1 2 QQYESVAAK 9 0 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 0 ; 144.77 0.0024432 31670000.0 56672.0 61563.0 65230.0 56199.0 50588.0 50340.0 58371.0 49147.0 48010.0 61391.0 False True 55863.846887628024 61420.45465591945 59867.04119508162 60332.061934368205 47612.51329983468 48187.075548271496 61393.16476850349 51430.54903994448 42602.608232287166 72002.35255163444 0.7758614115777239 0.8530339979082422 0.8314595158838689 0.8379179262386293 0.6612633006080005 0.6692430711026491 0.852654984078154 0.714289842169567 0.5916835592522608 1.0 16.135756424425637 -6.622592459661901 0.001609829793378367 1.5427826647441938 0.000187499654734786 0.00618745966549239 0.11417153448355283 3686525.593626621 2123.7926220851227 1012590.8150712344 1022482.7281763582 2.384556078400254e-07 6.622592459661901 -1.542595165089459 QRAREMT(ph)EVLPSQR ddPTM_PC-9_AZD4547_30min_R2 1 QRAREMTEVLPSQR 14 2 B5MCN3 B5MCN3 SEC14L6 Putative SEC14-like protein 6 1 QRAREMT(1)EVLPSQR 92.295 0.043071 0.0 5999.7 6071.1 8836.2 15657.0 11239.0 12186.0 8637.6 12370.0 9418.7 10116.0 True False 7907.479798487507 8033.464348168768 8719.026214529487 12047.520548238635 9678.658849261465 11424.007493600833 9406.329666751595 10458.500734321586 9916.553253342858 9761.841919070763 0.8100397306208608 0.8229455480604094 0.8931742889111913 1.2341441961585717 0.9914787526269206 1.1702717159640599 0.9635814372670144 1.0713655087868026 1.01584858017111 1.0 13.252937673925004 -5.563134757777324 10.151153498996877 1.0641743854223837 0.8267871678998663 0.6317629486706688 0.07896435301575837 0.2387578164571492 58.53045442664745 0.020226561239350172 0.03512408498711483 2.7344201280197615e-06 5.563134757777324 -0.23738721752251746 QRAS(ph)LSSAPVVLVGDHA ddPTM_PC-9_Lapatinib_30min_R1 2 QRASLSSAPVVLVGDHA 17 1 Q9HBH9 Q9HBH9 MKNK2 MAP kinase-interacting serine/threonine-protein kinase 2 1 QRAS(0.9)LS(0.085)S(0.015)APVVLVGDHA;QRAS(0.805)LS(0.153)S(0.042)APVVLVGDHA 92.26899999999999 0.00097895 10322800.0 21246.3 17400.9 20228.1 17797.9 20215.7 21715.0 20687.7 18581.2 25724.0 14592.4 True False 20943.32386590577 17360.609285158105 18565.02370072407 19106.81693805393 19026.652271595405 20786.300070137382 21758.807880306475 19444.550386005583 22826.6922342711 17114.676896849225 1.223705477592825 1.0143696775458353 1.084742867926525 1.1163995121386985 1.1117155401921828 1.2145306741936854 1.2713537048608976 1.1361330688974491 1.333749528071631 1.0 14.062946435922129 -6.735848273476995 7.05089931966629 1.204749309902338 1.1033867463302875 0.1438057790963828 0.09527698626203454 0.2700653051722247 48.80189909583722 0.029927293463549772 0.029215052630753562 1.8371800744082425e-07 6.735848273476995 -0.10136256357205053 QRDELNR ddPTM_PC-9_AZD4547_30min_R2 3 QRDELNR 7 1 P43034;I3L495 P43034 PAFAH1B1 Platelet-activating factor acetylhydrolase IB subunit alpha 0 ;; 102.77 0.01396 12147000.0 17560.0 13557.6 18807.9 22516.0 22760.3 18803.2 17851.9 18582.9 21503.1 22102.4 False True 23143.714729309904 17939.82906668195 18558.49495713644 17325.28406873226 19600.42521637563 17627.43293153415 19440.684516287256 15711.339797560591 22639.709966551294 21328.601703446966 1.085102298364435 0.8411160429604089 0.8701224400536843 0.8123028555562684 0.9189737559405011 0.8264692255322738 0.9114842494876446 0.7366324345126406 1.0614718339877123 1.0 14.38050176568604 -8.289575101274593 24.952704320188563 1.0307359852648614 0.8729026033509092 0.337121745969592 0.08714658749149161 880.6616428865618 781023.1879528379 0.07915250752883626 0.02045409597691855 5.133633953962187e-09 8.289575101274593 -0.15783338191395224 QRDELNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QRDELNR 7 1 P43034;I3L495 P43034 PAFAH1B1 Platelet-activating factor acetylhydrolase IB subunit alpha 0 ; 102.77 0.01396 7700700.0 16421.3 19146.4 19892.4 16451.7 23051.7 24760.0 16243.8 16192.6 19929.8 21335.0 False True 19201.101754540985 21047.128057850587 20366.7102583471 15529.964586131038 18534.884863013045 23461.54201251112 14705.069669072225 15767.561407477884 20221.23562152268 25202.86661223294 0.7618618171482594 0.8351084970482981 0.808110861820041 0.6161983406519764 0.7354276459177307 0.9309076770308097 0.5834681385781209 0.6256257135378657 0.802338715378818 1.0 14.621300216927272 -8.545383669135438 21.76500285383417 1.0000000059088172 0.7383534844239849 0.3769090040222711 0.10172750038258009 1050.2129891125073 1015684.1947974858 0.1022855163185338 0.026410006783069182 2.848500702275191e-09 8.545383669135438 -0.26164652148483236 QRDELNR ddPTM_PC-9_Lapatinib_30min_R1 3 QRDELNR 7 1 P43034;I3L495 P43034 PAFAH1B1 Platelet-activating factor acetylhydrolase IB subunit alpha 0 ;; 120.62 0.0077461 15241000.0 20954.3 18945.300000000003 19712.3 18721.8 18574.8 16700.2 21703.5 21550.0 22295.5 17677.0 False True 20655.487839452013 18901.43332184576 18091.630785678473 20098.663626093974 17482.266783461866 15985.971376067613 22827.201033958903 22551.29167214282 19784.34600797665 20732.445896878067 0.9962880377062678 0.9116837162320524 0.8726240442476084 0.9694304148224243 0.8432322394770788 0.7710605615748797 1.101037530617469 1.0877294355095188 0.9542697521740942 1.0 14.339602707050384 -7.2780846840659175 24.99974047421538 1.0430699679772835 0.8949966964616238 0.4910942467209113 0.07050833633564536 727.2031151986027 1092188.8970076726 0.030379294834173082 0.020543224106028858 5.2712706569900564e-08 7.2780846840659175 -0.14807327151565963 QREESYSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QREESYSR 8 1 P23246;P23246-2;H0Y9K7;H0Y9U2 P23246 SFPQ Splicing factor, proline- and glutamine-rich 0 ;;; 89.88600000000001 0.012819 12317800.0 18221.7 15400.599999999999 21779.600000000002 23398.199999999997 26638.7 22317.4 20175.4 18823.6 19676.0 20202.0 False True 21306.273915020116 16929.469788980372 22298.908263592955 22087.27471198789 21419.037962507988 21147.036256462674 18264.24005475317 18329.500445252797 19963.724276665118 23864.462681055982 0.8928034207086255 0.7094008365174412 0.9343980864607612 0.925529939943762 0.8975286076526997 0.8861308355896717 0.7653321299897372 0.7680667564245253 0.8365461457681451 1.0 14.5425762333876 -9.744227072651858 16.13865061444907 1.0000137072019712 0.8451058079336677 0.290652259179786 0.07206620534245502 0.0 0.0 0.0739503024300382 0.017935582821495172 1.8020752720439407e-10 9.744227072651858 -0.1549078992683035 QREEYER ddPTM_PC-9_AZD4547_30min_R2 1 QREEYER 7 1 P12270;P12270-2 P12270 TPR Nucleoprotein TPR 0 76.47800000000001 0.040441000000000005 1549400.0 3575.2 2565.2 4754.3 5310.2 6054.5 5975.3 4876.7 5718.2 4963.4 4674.0 False True 4712.039231220318 3394.350734779944 4691.254875595568 4086.015431772162 5213.937183277291 5601.663546406783 5310.71685258029 4834.583581163918 5225.755191018068 4510.364682654877 1.0447135792236497 0.7525668041507394 1.0401054472682276 0.9059168646573972 1.155990158252188 1.2419535759377998 1.1774473299250634 1.0718830784916045 1.1586103472107938 1.0 12.13902837104459 -6.263661197220886 24.956842783258054 1.1454468793585342 0.9301843043490452 0.4977643855825321 0.09722393645990923 148.77473198176128 1671127.681325138 0.028584815799624134 0.03400329093623078 5.449275971981818e-07 6.263661197220886 -0.21526257500948898 QREEYER ddPTM_PC-9_Lapatinib_30min_R1 1 QREEYER 7 1 P12270;P12270-2 P12270 TPR Nucleoprotein TPR 0 94.11399999999999 0.017567 2384900.0 7761.6 7318.1 6397.5 4140.1 7962.9 6902.5 6083.0 7027.5 8260.1 4679.0 False True 7650.918160696886 7301.155389072728 5871.52224506415 4444.576764968737 7494.53787766375 6607.296165513391 6397.947975652408 7354.02330515006 7329.760555290885 5487.7589156243985 1.3941789860545217 1.330443902753334 1.0699307923945283 0.8099074382284579 1.3656827847021082 1.2040062741643984 1.1658580622841461 1.3400776925918068 1.3356564433656255 1.0 12.422001388098304 QRELEIEER ddPTM_PC-9_Lapatinib_30min_R1 2 QRELEIEER 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 ; 101.97 0.0043115 3846500.0 27794.0 19748.5 25311.0 24161.0 25955.2 25896.0 22613.0 17017.6 25669.0 17166.8 False True 27397.652463204635 19702.77356159423 23230.02728328547 25937.88053873327 24428.566165886554 24788.488446524396 23783.790493741242 17808.29982180313 22777.886913446782 20134.058506676833 1.36076154015938 0.9785793338715301 1.1537677451161652 1.2882589235613764 1.2132956779571085 1.2311719685479243 1.1812715496904953 0.8844863451597483 1.1313112508286993 1.0 14.297350391217002 -7.659673760348624 8.421102338781282 1.0065435694547722 1.1966304246353494 0.4080515193665999 0.10805933191459308 0.25302894330111747 18.670566848887614 0.050070313575879606 0.028777294337854475 2.1894056759998362e-08 7.659673760348624 0.19008685518057722 QRELEQLGR ddPTM_PC-9_AZD4547_30min_R2 2 QRELEQLGR 9 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 93.598 0.0079499 4921800.0 23362.0 26942.0 25187.0 42863.0 34088.0 37651.0 30369.0 30982.0 32794.0 34311.0 False True 30790.630040212887 35650.47462047452 24853.003923106568 32981.59757674856 29355.469601710545 35296.67701801782 33071.782167451514 26194.44379553367 34527.42388972209 33109.782333455616 0.9299556768484294 1.076735396851331 0.7506242014159656 0.996128492920428 0.8866101657227887 1.0660498055389651 0.9988522979214604 0.7911391120522596 1.042816396132995 1.0 15.014969905914795 QRELEQLGR ddPTM_PC-9_Lapatinib_30min_R1 1 QRELEQLGR 9 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 131.62 0.0015917 3403600.0 18358.0 15259.0 17703.0 17531.0 16737.0 16231.0 12503.0 14083.0 16237.0 12648.0 False True 18096.211553555117 15223.668723010174 16247.527675556179 18820.288221701616 15752.562566208051 15536.837966308996 13150.344162351152 14737.34759251913 14408.21807680998 14834.189947599352 1.2198988699402264 1.026255479860149 1.095275693040829 1.2687102085238797 1.0619091855944127 1.0473667939531377 0.8864888617985709 0.9934716789105229 0.9712844535297118 1.0 13.856638527096363 -6.801542520534948 2.421731624984384 0.9639868456911284 1.1392960606786453 0.5668069778558971 0.07137180594870249 0.22140405780938954 2.6600387537562447 0.027759878925493094 0.02503709987087364 1.579273977954879e-07 6.801542520534948 0.17530921498751695 QRHS(ph)YPER ddPTM_PC-9_AZD4547_30min_R2 2 QRHSYPER 8 1 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 QRHS(1)YPER;QRHS(1)YPER 86.189 0.0059745 12094900.0 19634.5 21591.6 27374.0 46086.0 31710.0 30457.7 29297.0 32165.0 26345.0 31475.0 True False 25877.86257702936 28570.662453249115 27011.002874146125 35461.584721602194 27307.61385444265 28553.175204156094 31904.376244190684 27194.638328169258 27737.54291561653 30373.0698302444 0.852000233155923 0.9406577146442895 0.8893076342006612 1.1675337698756691 0.8990732252967963 0.940081966154237 1.050416583588843 0.895353630046635 0.9132281679343618 1.0 14.890505109755507 QRHS(ph)YPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QRHSYPER 8 1 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 QRHS(0.999)Y(0.001)PER 72.096 0.01586 5671200.0 2794.1 8041.4 7498.4 7669.1 9554.5 8071.6 8494.4 6832.3 9641.3 8569.3 True False 3267.085944009486 8839.697048238819 7677.190293840353 7239.425190557671 7682.3643125521385 7648.311086760285 7689.748937869648 6652.959364420238 9782.2857729524 10122.846255458528 0.32274380757761484 0.8732422507624475 0.7584023406164637 0.7151570820957561 0.7589134635339926 0.7555494663999365 0.7596429644205173 0.6572222077197678 0.9663572404527544 1.0 13.305327371290845 -5.855868674151443 0.0644431263427577 1.4040110434963657 7.085407333987216e-11 0.3992588668398176 0.13793079279329326 113.73564602970897 1.7514678553489411 13.61589271212507 25.05689029660714 1.3935781418567907e-06 5.855868674151443 -1.4040110434255118 QRHS(ph)YPER ddPTM_PC-9_Lapatinib_30min_R1 2 QRHSYPER 8 1 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 QRHS(1)YPER;QRHS(1)YPER 95.48299999999999 0.0030256999999999997 12468800.0 20586.9 18524.0 19856.2 16813.7 18377.199999999997 17038.8 17281.7 16164.8 23156.0 17069.5 True False 20293.327030824905 18481.10881611117 18223.699883148543 18050.235586858973 17296.289226965313 16310.090243382767 18176.461865992485 16915.875620503673 20547.92743650994 20019.94033132094 1.0136557199961407 0.923135059858181 0.9102774324775483 0.9016128563889678 0.8639530858094262 0.8146922504991605 0.9079178841285378 0.8449513505312003 1.0263730608808543 1.0 14.289150053831465 -8.272917480599002 24.79512614623386 1.013186558872933 0.8954058494987923 0.45528678368213116 0.05056241089048781 700.1878078445274 1512536.0146132961 0.049353860352867755 0.013201238851068648 5.334362429819499e-09 8.272917480599002 -0.11778070937414065 QRLEAEAGR ddPTM_PC-9_AZD4547_30min_R2 2 QRLEAEAGR 9 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 99.788 0.005222 10853600.0 28310.0 29603.0 44956.0 54304.0 48350.0 37526.0 34596.0 47878.0 34700.0 42081.0 False True 37311.99111541933 39171.590831783345 44359.854066271444 41785.0517884365 41637.437081750315 35179.493287778205 37674.976978667444 40479.55522698858 36534.17115854598 40607.75699845953 0.918839006962014 0.9646332062435591 1.0923985303584793 1.0289918694603504 1.0253567337720684 0.8663244633066719 0.9277778376209417 0.9968429240877349 0.8996845395802558 1.0 15.30946772061203 -6.726497698967457 24.999713475539775 0.9372817707340052 1.0098156824833786 0.2650657154334968 0.05636251584287382 251.08654517655984 179644.15907402 0.01936710801790795 0.019366267070300286 1.8771643641722342e-07 6.726497698967457 0.0725339117493734 QRLEAEAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QRLEAEAGR 9 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 85.86200000000001 0.015694999999999997 6299900.0 27205.0 19637.0 29849.0 32476.0 31087.0 33234.0 31987.0 27149.0 28411.0 23425.8 False True 31810.269176757487 21586.431583588128 30560.713362962895 30656.475008612586 24995.72550989672 31491.15053488668 28956.959794174585 26436.367516743256 28826.457126668654 27672.71210146922 1.1495175846919823 0.7800620157661398 1.1043627834851917 1.107823291631215 0.9032625865597622 1.1379856957791545 1.046408450606371 0.9553226087781861 1.0416925171977696 1.0 14.756176423699605 -1.6517987506456984 15.93405861302996 1.0198474821646977 1.0115827241831254 0.0 0.11067191713673397 0.0 0.0 0.024006858789861002 0.0 0.022294680315172608 1.6517987506456984 -0.008264757981572224 QRLEAEAGR ddPTM_PC-9_Lapatinib_30min_R1 2 QRLEAEAGR 9 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 99.01299999999999 0.0055447 8438200.0 33011.0 24370.0 28156.0 24175.0 24324.0 26448.0 22748.0 22102.0 29167.0 21197.0 False True 32540.257086524 24313.57276228834 25841.122365303057 25952.91014543591 22893.31014282398 25316.880693299263 23925.780133181164 23128.939607317912 25881.905317873767 24860.873206772892 1.3088943745410762 0.9779854697808663 1.0394293937456354 1.0439259284893305 0.9208570411994665 1.0183423760997317 0.9623869577784187 0.9303349651056043 1.0410698410554104 1.0 14.601589349671011 -4.7599936747086105 24.99813545047956 0.99119600091821 1.3088947622588736 0.8327689331380125 0.04250278096118555 14.006813635697252 242112.17697401164 0.010579603684178969 0.06460537788009242 1.7378261391715075e-05 4.7599936747086105 0.31769876134066355 QRMAEES(ph)ISRNEET(ph)S(ph)EES(ph)QEDEK ddPTM_PC-9_AZD4547_30min_R2 1 QRMAEESISRNEETSEESQEDEK 23 2 P16383-4;P16383 P16383-4 GCFC2 GC-rich sequence DNA-binding factor 2 4 QRMAEES(0.856)IS(0.189)RNEET(0.978)S(0.978)EES(1)QEDEK 57.496 0.036407 0.0 2172.5 523.99 1998.5 2044.6 2202.4 1158.1 1180.5 2600.3 2129.6 850.12 True False 2863.309809192812 693.3595203170674 1971.998584203298 1573.2490587551067 1896.634776191248 1085.6838239241038 1285.5622130684749 2198.483383949588 2242.166308335432 820.3575575563896 3.4903192916534986 0.8451918482745342 2.4038281430323107 1.917760181842373 2.311961118321114 1.3234275882799753 1.567075479743 2.679908734550141 2.733157374711344 1.0 9.68010904350516 -4.731688319386443 24.655152695555458 1.923465495879781 3.490330477204172 0.3633953722571823 0.6412518786587454 3628.695113799684 3006958.6111575444 0.157169194382083 18.40635316874552 1.8548623270045783e-05 4.731688319386443 1.566864981324391 QRNQT(ph)PLPLIKPY(ph)S(ph)GPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QRNQTPLPLIKPYSGPR 17 2 Q16594;D6RIE8;D6RIY1;D6RGK3;D6RIV9 Q16594 TAF9 Transcription initiation factor TFIID subunit 9 3 QRNQT(1)PLPLIKPY(1)S(1)GPR 56.72 0.04525 0.0 2331.6 2957.4 2029.8 2701.5 2053.7 2239.7 1853.1 2558.8 2283.4 1038.0 True False 2726.2938288008745 3250.991127224298 2078.198130059366 2550.143713381173 1651.2922276088045 2122.2461892334863 1677.5609527178203 2491.634211272706 2316.790405231607 1226.1811831965217 2.22340210905351 2.6513138284746107 1.6948540383255013 2.0797446155006423 1.346695129755673 1.7307769996119335 1.3681183300697866 2.032027766710043 1.8894356209185865 1.0 10.25995645519668 -1.522878745280338 0.2809856720098967 1.4679015376561575 9.277430669076423 0.4391633502551897 0.34252419277444357 50.67537529387715 0.7148337861403483 0.3774192580100495 194.52403587580244 0.029999999999999964 1.522878745280338 7.809529131420266 QRPDLGS(ph)AQK ddPTM_PC-9_AZD4547_30min_R2 4 QRPDLGSAQK 10 1 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;E5RFR3;A0A3B3IU45 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 QRPDLGS(1)AQK;QRPDLGS(1)AQK;QRPDLGS(1)AQK;QRPDLGS(1)AQK 101.32 0.017603 120526000.0 146284.0 125722.0 184285.0 217120.0 213481.0 206806.0 179177.0 202902.0 157601.0 183576.0 True False 192799.26910378 166359.17787229244 181841.26049032007 167066.33847056085 183842.84810029212 193874.38812749222 195123.40588815758 171548.1581241164 165931.46711118164 177149.06011618598 1.0883448604092485 0.9390915072492237 1.026487300418397 0.9430834031012514 1.037786189662626 1.094413868187258 1.101464528009253 0.968383112005245 0.9366770955620815 1.0 17.434604285536196 -7.957809949382152 24.998111121860163 0.9630687724565811 1.0286687918702746 0.21853283816760216 0.055389654388604555 217.9670172936745 129147.79720214114 0.03190236560308135 0.015325380400443497 1.1020214571347422e-08 7.957809949382152 0.06560001941369353 QRPDLGS(ph)AQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QRPDLGSAQK 10 1 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;E5RFR3;A0A3B3IU45 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 QRPDLGS(1)AQK;QRPDLGS(1)AQK 113.99 0.0060108 39016000.0 75971.0 92219.0 76634.0 81393.0 102063.0 87426.0 92620.0 72966.0 73732.0 65596.0 True False 88831.38980435378 101373.89286586115 78461.24519606354 76832.81408966653 82064.48781537592 82841.2266553229 83846.36308926893 71050.71981386737 74810.19101276042 77488.03554234962 1.1463884609102608 1.3082521986308089 1.012559482853092 0.9915442242393021 1.0590601147776566 1.069084098925796 1.0820556038415026 0.9169250364468969 0.9654418322667933 1.0 16.241685949339697 -5.275081052807433 24.79662951471623 1.0145957124348446 1.2273203241368 0.6772427145838822 0.059414696788512494 355.55501179785676 646296.7280092573 0.016112802761948663 0.03383846218909808 5.3078537398871065e-06 5.275081052807433 0.21272461170195545 QRPDLGS(ph)AQK ddPTM_PC-9_Lapatinib_30min_R1 2 QRPDLGSAQK 10 1 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;E5RFR3;A0A3B3IU45 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 QRPDLGS(1)AQK;QRPDLGS(1)AQK 109.16 0.004777 85271000.0 271688.0 259284.0 228060.0 236435.0 253109.0 197943.0 197646.0 182933.0 227453.0 149871.0 True False 267813.6792985223 258683.643828362 209309.78713705787 253823.21862403874 238221.62625144018 189477.4393176701 207879.1427906946 191432.73500975006 201834.84795372668 175776.00265944563 1.5236077464874063 1.4716664386181568 1.1907756688640925 1.4440151942458517 1.3552568191744514 1.0779482776427116 1.1826366491758644 1.08907206964217 1.1482503009513099 1.0 17.423378598346098 -1.8119903940170707 0.16756098108580067 0.9488305348324949 3.109834397550952 0.73346635099371 0.09076471204454897 29.137098247395397 0.3399910003536928 0.25409589382797965 15.418387220091732 0.015417345535716824 1.8119903940170707 2.161003862718457 QRPVPQPSSAS(ph)LDEYTLMR ddPTM_PC-9_AZD4547_30min_R2 3 QRPVPQPSSASLDEYTLMR 19 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 QRPVPQPSS(0.001)AS(0.741)LDEYT(0.258)LMR;QRPVPQPS(0.006)S(0.003)AS(0.906)LDEY(0.004)T(0.081)LMR;QRPVPQPS(0.095)S(0.018)AS(0.807)LDEY(0.001)T(0.08)LMR 121.48 1.7964e-05 113224000.0 90492.0 73433.1 103641.0 122797.0 123776.0 112011.0 108181.0 127864.0 95782.3 114392.0 True False 119266.5736494709 97168.91351246262 102266.65262217354 94488.04884473784 106591.8389292809 105006.93446296768 117808.89942563351 108105.55682241658 100845.1568345591 110387.1708982148 1.0804387201792096 0.8802554927515952 0.9264360322855907 0.855969476125653 0.965617997652703 0.9512603104919856 1.0672336148035002 0.9793308039581697 0.9135586682219246 1.0 16.75221298752207 -6.7928121850609635 2.8105300673401694 0.989076460905515 0.9308953877562587 0.09170458446784868 0.0663791976563536 0.560047773682221 9.059797188564556 0.024878783328922342 0.022673187973582906 1.61134232542899e-07 6.7928121850609635 -0.05818107314925636 QRPVPQPSSAS(ph)LDEYTLMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QRPVPQPSSASLDEYTLMR 19 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 QRPVPQPS(0.001)S(0.009)AS(0.978)LDEY(0.004)T(0.009)LMR 74.859 0.0064245000000000005 13827000.0 18959.0 24299.0 26846.0 20959.0 32082.0 27166.0 29973.0 26267.0 27204.0 22212.0 True False 22168.384242681317 26711.244133503486 27486.110454021946 19784.735179994812 25795.76240256398 25741.36713699018 27133.740454271865 25577.519082187027 27601.807035088324 26238.859769904735 0.8448684293860915 1.0180032351916666 1.0475344849225412 0.7540241974495923 0.9831129335944325 0.981039853207144 1.0341051666198366 0.9747953724545513 1.0519438450121545 1.0 14.679417407430527 -6.506141345857333 24.880844227705737 1.005483693475627 0.9247478758660475 0.22748877091160424 0.07990462653936747 1226.2183844909569 1822827.7329440343 0.025493239069140017 0.028198597095162974 3.1178746727609323e-07 6.506141345857333 -0.0807358176095796 QRPVPQPSSAS(ph)LDEYTLMR ddPTM_PC-9_Lapatinib_30min_R1 3 QRPVPQPSSASLDEYTLMR 19 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 QRPVPQPS(0.001)S(0.013)AS(0.856)LDEY(0.005)T(0.124)LMR;QRPVPQPS(0.005)S(0.091)AS(0.903)LDEYT(0.001)LMR;QRPVPQPS(0.002)S(0.006)AS(0.985)LDEYT(0.006)LMR 178.45 3.6005999999999997e-09 97830000.0 103634.0 82652.0 101532.0 88568.0 101624.0 100100.0 81457.0 94219.0 114154.0 80629.0 True False 102156.1601558518 82460.62437212381 93184.43088485418 95081.58617418689 95646.67612047128 95818.95634449707 85674.44488783785 98596.75870336985 101296.77442508866 94565.6152186107 1.0802674938421726 0.8719937387547962 0.9853944340068682 1.0054562216338718 1.0114318602946901 1.0132536664937777 0.9059788242246526 1.042628004644608 1.0711797749204857 1.0 16.529028083503157 -7.910067112853112 24.999690301426785 1.0427645149161162 0.98062308492085 0.16618188008454438 0.05708832674539978 29.67030889700132 8236.997906300201 0.030074560863307627 0.01444735144891476 1.2300786683095418e-08 7.910067112853112 -0.06214142999526617 QRPVPQPSSASLDEYT(ph)LMR ddPTM_PC-9_Lapatinib_30min_R1 1 QRPVPQPSSASLDEYTLMR 19 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 QRPVPQPSS(0.001)AS(0.243)LDEYT(0.756)LMR 108.28 0.00012068 68405000.0 73111.0 48709.0 63168.0 61371.0 70021.0 65655.0 58519.0 66637.0 79235.0 58603.0 True False 72068.42373308467 48596.21730317202 57974.57087553141 65884.42806765456 65902.5024465827 62847.088699280175 61548.82748433394 69733.19829032854 70310.71991846015 68732.45046641082 1.048535637010412 0.7070345517059766 0.8434817976388499 0.958563642363543 0.9588266095472457 0.9143728802451646 0.8954842591333553 1.0145600486688129 1.0229625081215548 1.0 16.068703775152358 -7.152968454204005 0.5684192906855814 1.0191014175198867 0.8652991565658265 0.2137166861576747 0.08625306900900338 1.2528134869965768 0.8478734889032256 0.07918668308256278 0.06727149830394148 7.031233907180775e-08 7.152968454204005 -0.15380226095406024 QRPY(ph)SVAVPAFSQGLDDYGAR ddPTM_PC-9_Lapatinib_30min_R1 1 QRPYSVAVPAFSQGLDDYGAR 21 1 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 QRPY(0.83)S(0.17)VAVPAFSQGLDDYGAR 67.214 0.017495 3811900.0 19107.0 18344.0 17394.0 12860.0 15691.0 17336.0 14349.0 13999.0 16015.0 13303.0 True False 18834.530676205337 18301.525595051997 15963.932462781691 13805.767299702398 14768.086229692924 16594.579692189807 15091.92100980379 14649.444645862059 14211.222054573605 15602.405824866717 1.2071555430373015 1.1729938190611278 1.0231712110281597 0.8848486223643227 0.9465262213700354 1.0635910819433878 0.9672816602264421 0.9389221643314871 0.9108353041249653 1.0 13.929480883251964 -5.315970245704338 3.068232681332096 0.9601344462838207 1.1995704162997651 0.7925643627035921 0.04666131445735875 0.11259496625982485 2.0837142100113915 0.013423190639399441 0.03584066032832311 4.830918984004009e-06 5.315970245704338 0.2394359700159444 QRPYS(ph)VAVPAFSQGLDDYGAR ddPTM_PC-9_AZD4547_30min_R2 1 QRPYSVAVPAFSQGLDDYGAR 21 1 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 QRPY(0.453)S(0.547)VAVPAFSQGLDDYGAR 57.248000000000005 0.0068991 5638500.0 13600.0 12681.0 19580.0 27227.0 17495.0 18789.0 26764.0 14745.0 15027.0 12764.0 True False 17924.517102426817 16779.885259529252 19320.35640665526 20950.235802956715 15066.12123568193 17614.12085977894 29145.944151261883 12466.499056392215 15821.29654177147 12317.136245059231 1.4552503719861727 1.3623203418132328 1.5685753589358264 1.7009015233845834 1.2231837771320748 1.4300500140074757 2.366292259124209 1.0121264235745462 1.2844947256402932 1.0 13.588379245541077 QRPYS(ph)VAVPAFSQGLDDYGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QRPYSVAVPAFSQGLDDYGAR 21 1 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 QRPY(0.185)S(0.815)VAVPAFSQGLDDYGAR 67.01 0.0017994 2863100.0 16612.0 13320.0 11659.0 13589.0 15138.0 12328.0 16453.0 13557.0 8435.1 8852.0 True False 19424.0834980443 14642.321571186741 11936.99477700373 12827.652386132415 12171.81756904225 11681.497977796333 14894.452730595374 13201.14311482885 8558.447379858606 10456.79752760655 1.8575556662318073 1.4002682496749284 1.1415535918611195 1.226728580358056 1.1640100649274263 1.1171200309613438 1.4243799491453437 1.262446086383242 0.8184577885594333 1.0 13.352153462639809 -4.768133319059543 1.9838115172886877 1.1645623870793544 2.0827295647723227 0.67168600321653 0.15241717230013088 0.482491336894972 2.01072689268834 0.041036431655570464 0.8297848660479046 1.7055587388048844e-05 4.768133319059543 0.9181671776929683 QRS(ph)APDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QRSAPDLK 8 1 O43896 O43896 KIF1C Kinesin-like protein KIF1C 1 QRS(1)APDLK 57.175 0.038983 9982300.0 85460.0 54307.0 53563.0 79356.0 96210.0 73029.0 84768.0 76717.0 85274.0 72364.0 True False 99926.69008806082 59698.24005754043 54840.14505880868 74909.94059562309 77358.34114926362 69199.2306797929 76738.16137282614 74703.26003838063 86520.97092744161 85483.02036689123 1.168965364807861 0.698363719500281 0.6415326087383904 0.8763136851518732 0.9049556370053765 0.8095084893209358 0.8977006315811918 0.873895888537348 1.012142183981047 1.0 16.383350263112845 -8.107244551961616 1.4861294436347203 1.013555393898554 0.8389995882517725 0.15234767534157567 0.1335722163696915 0.7319345269040841 2.9162734532183037 0.123147219754133 0.039428649798939716 7.811877925391927e-09 8.107244551961616 -0.17455580564678153 QRS(ph)APDLK ddPTM_PC-9_Lapatinib_30min_R1 1 QRSAPDLK 8 1 O43896 O43896 KIF1C Kinesin-like protein KIF1C 1 QRS(1)APDLK 58.511 0.036506 11910000.0 65171.0 58724.0 69827.0 56777.0 73680.0 68343.0 66539.0 58712.0 66633.0 64694.0 True False 64241.64958910228 58588.02818599181 64086.0936000148 60952.56998251974 69346.28726045346 65420.12920531422 69984.06384217263 61439.973858693724 59128.089863403315 75876.2717006636 0.8466632340943083 0.7721521744917181 0.8446131071494689 0.8033153002427591 0.9139390445280271 0.8621948303337902 0.9223445258125482 0.8097389668943945 0.779269836776735 1.0 16.21136117096213 -6.241851540196778 24.615153956832778 0.8728369991911659 0.8154997617951234 0.20553156297649622 0.06083293421794552 1240.03568983628 1558296.6452315361 0.01773180525033485 0.022855533362426333 5.729918698137663e-07 6.241851540196778 -0.05733723739604246 QRS(ph)DDESPSTSSGSSDADQR ddPTM_PC-9_AZD4547_30min_R2 1 QRSDDESPSTSSGSSDADQR 20 1 R4GMM6;R4GN77;R4GNG6;R4GND1;A0A1B0GX65;Q969T4 R4GMM6 UBE2E3 Ubiquitin-conjugating enzyme E2 E3 1 QRS(1)DDESPSTSSGSSDADQR 131.48 1.8913e-05 2041000.0 0.0 1163.9 557.02 929.06 966.34 2029.4 2070.3 1857.2 2358.2 789.34 True False 0.0 1540.1079136949863 549.6335508495973 714.8795708339137 832.1803712425766 1902.501297186406 2254.55268929747 1570.2124142103517 2482.849637639282 761.7054468563973 0.0 2.02192057317051 0.7215828022734602 0.938524955787389 1.092522542246525 2.4976863498063975 2.959874710890069 2.061443069221455 3.25959286215708 1.0 9.573089402042434 -6.747191117843899 6.582713600531011 2.4629419101943686 0.9943041951366146 0.4769745406889828 0.728838414948301 0.12562209332478497 22.202099247915307 0.23065726413407867 0.22136556631081314 1.7898180442505107e-07 6.747191117843899 -1.468637715057754 QRS(ph)IQEDTK ddPTM_PC-9_AZD4547_30min_R2 1 QRSIQEDTK 9 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1;H7BZ98 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 QRS(0.872)IQEDT(0.128)K 92.19 0.034848000000000004 6291600.0 30988.0 28959.0 37504.0 39764.0 40209.0 38086.0 34636.0 45444.0 39325.0 37650.0 True False 40841.53940955897 38319.430425889754 37006.672455321735 30597.024147675867 34626.67440786136 35704.47639925172 37718.536901177205 38421.67399923283 41403.63921642132 36331.88495976812 1.124123877822045 1.0547052669665373 1.0185728732847426 0.8421535018498844 0.9530657285248203 0.982731186085964 1.0381662537725358 1.0575194224516242 1.1395951314463693 1.0 15.148948596708419 -7.5325070546713 2.650419668745134 1.0742860490339579 0.9909463043917192 0.1468526435597216 0.07502495485573918 0.5339356629440738 7.546953787058322 0.04405488926271631 0.024010526544382054 2.9342218401251063e-08 7.5325070546713 -0.0833397446422387 QRS(ph)IQEDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QRSIQEDTK 9 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1;H7BZ98 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 QRS(0.999)IQEDT(0.001)K;QRS(1)IQEDTK 76.357 0.011623 16269400.0 91370.0 77199.0 101886.0 118138.0 134564.0 101634.0 120165.0 122645.0 98247.0 95502.0 True False 106837.13636024001 84862.80652958293 104315.34864480657 111519.11086856356 108197.15017575637 96304.13412356847 108782.10128073895 119425.69870311877 99683.67650993694 112815.75660658405 0.9470054500703041 0.7522247696792935 0.9246522984247628 0.9885065191510242 0.9590606261948508 0.8536408124213036 0.964245638666313 1.0585905931525612 0.883597110087717 1.0 16.783609052728977 -5.506492282595265 23.59755098840729 0.9566007950895014 0.8468209302509607 0.2759158461806194 0.06948636354629055 402.3041551814538 579340.8859172197 0.017835164629787202 0.035521290443358534 3.1153562553036627e-06 5.506492282595265 -0.10977986483854063 QRS(ph)IQEDTK ddPTM_PC-9_Lapatinib_30min_R1 2 QRSIQEDTK 9 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1;H7BZ98 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 QRS(0.997)IQEDT(0.003)K;QRS(1)IQEDTK 75.73899999999999 0.012047 26405000.0 185774.0 191346.0 216120.0 171948.0 259620.0 223074.0 199665.0 221060.0 256570.0 231810.0 True False 183124.82869322062 190902.950093263 198351.4478473254 184593.62952171295 244349.66203255855 213533.6450308921 210002.67673165174 231331.25461920665 227672.38479812382 271878.0496325906 0.6735550330035509 0.702163894257902 0.7295603602989382 0.6789574582102832 0.8987472963071743 0.7854022982710678 0.7724149743439908 0.8508640360331483 0.8374062750037922 1.0 18.052600152961915 -6.204106444985301 0.05204414282152011 1.514772197191035 8.579186441154982e-20 0.7599556275212036 0.04884260389250034 61.40244560280616 0.899961359341929 10.428913720545467 15.756430377583952 6.250194825777574e-07 6.204106444985301 -1.514772197191035 QRS(ph)PIALPVK ddPTM_PC-9_Lapatinib_30min_R1 3 QRSPIALPVK 10 1 Q8TF01;Q8TF01-2 Q8TF01 PNISR Arginine/serine-rich protein PNISR 1 QRS(1)PIALPVK;QRS(1)PIALPVK;QRS(1)PIALPVK 92.23899999999999 0.0035667999999999997 77002500.0 243502.0 312447.0 338830.0 259168.0 358964.0 332437.0 334189.0 336565.0 355113.0 254289.0 True False 240029.6168272016 311723.54816818587 310972.70532162423 278228.07927910314 337850.4432703773 318219.44445849664 351491.6712206647 352203.03859093884 315116.43443433015 298242.51483120647 0.8048135490107737 1.0452015814868283 1.0426840234284591 0.9328920775650289 1.1328044342088095 1.0669821659685117 1.178543144392392 1.1809283421254408 1.0565778477715482 1.0 18.186126404640937 -6.265522185708249 24.952383018656104 1.1136980768020723 0.9689042337331828 0.42737983712453254 0.08182271642405196 336.91847644968243 2059103.0458624163 0.02476965309158148 0.029140620486187933 5.425975323076355e-07 6.265522185708249 -0.14479384306888954 QRS(ph)PIALPVKQEPPQIDAVK ddPTM_PC-9_AZD4547_30min_R2 4 QRSPIALPVKQEPPQIDAVK 20 2 Q8TF01;Q8TF01-2 Q8TF01 PNISR Arginine/serine-rich protein PNISR 1 QRS(1)PIALPVKQEPPQIDAVK;QRS(1)PIALPVKQEPPQIDAVK;QRS(1)PIALPVKQEPPQIDAVK;QRS(1)PIALPVKQEPPQIDAVK 88.19 0.00022952 60202200.0 138243.0 109262.0 157967.0 237272.0 231296.0 173790.0 144550.0 164082.0 145731.0 183888.0 True False 182201.39836696998 144578.80476513572 155872.25436619564 182572.60621585711 199184.54285957656 162922.8838267591 157414.6699695452 138726.89712926082 153434.04314426705 177450.13709115077 1.0267751907871372 0.8147573573914455 0.8784003040027452 1.0288670902636445 1.1224817637489988 0.9181333218304054 0.8870924111413115 0.781779599629168 0.8646600428685643 1.0 17.4370541634068 -10.859418265163402 6.391028281060092 1.0000043978511322 0.9235397968528836 0.04828564427618387 0.10006043438041766 6.8736709825634284e-06 7.136012071939396e-07 0.10620931349624312 0.02575806088869776 1.3822345199179612e-11 10.859418265163402 -0.07646460099824859 QRS(ph)PIALPVKQEPPQIDAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QRSPIALPVKQEPPQIDAVK 20 2 Q8TF01;Q8TF01-2 Q8TF01 PNISR Arginine/serine-rich protein PNISR 1 QRS(1)PIALPVKQEPPQIDAVK;QRS(1)PIALPVKQEPPQIDAVK 124.29 3.0132e-06 21976000.0 152438.0 86265.0 107355.0 200467.0 190140.0 208982.0 184803.0 222832.0 207606.0 127563.0 True False 178242.74261226092 94828.81909447638 109914.75034610498 189235.4839127834 152883.4319314109 198022.61602821495 167297.1219821442 216982.89611001962 210641.84499803503 150689.16211184778 1.1828504460059426 0.6293008585719687 0.7294137733974635 1.2558002265108152 1.0145615636108882 1.3141131933644592 1.110213366625327 1.4399369740271424 1.3978566344518384 1.0 17.201216133378146 -5.767394560361428 24.997779121398427 1.2281780033431953 0.8253995865565683 0.43861582580838676 0.1920501449695028 118.71759717315497 498337.51296226925 0.05354003532778442 0.08181458753676533 1.7084624566168693e-06 5.767394560361428 -0.40277841678662696 QRS(ph)PIALPVKQEPPQIDAVK ddPTM_PC-9_Lapatinib_30min_R1 2 QRSPIALPVKQEPPQIDAVK 20 2 Q8TF01;Q8TF01-2 Q8TF01 PNISR Arginine/serine-rich protein PNISR 1 QRS(1)PIALPVKQEPPQIDAVK;QRS(1)PIALPVKQEPPQIDAVK 112.82 1.1214000000000001e-05 34203000.0 264100.0 145844.0 184431.0 171834.0 178321.0 170759.0 133662.0 122799.0 191837.0 116126.0 True False 260333.8855699912 145506.30717862849 169267.7951042482 184471.2455814206 167832.50937257495 163456.03562867074 140582.364346811 128504.68983978948 170230.2969268337 136198.22437183128 1.9114337706728124 1.0683421744279533 1.2428047126527473 1.3544320892011072 1.2322665008787466 1.2001333819332594 1.0321894062510732 0.9435122258933576 1.2498716316748177 1.0 17.055348369367913 -4.757415520888033 24.999848037185206 1.1554998086747716 1.9114348662946687 0.7710952041308796 0.12486331255990558 59.7822033251393 371370.46870781004 0.03325159894835099 0.24736283789865235 1.7481732846150217e-05 4.757415520888033 0.7559350576198971 QRTS(ph)GSGFHR ddPTM_PC-9_AZD4547_30min_R2 2 QRTSGSGFHR 10 1 Q15007 Q15007 WTAP Pre-mRNA-splicing regulator WTAP 1 QRT(0.189)S(0.623)GS(0.188)GFHR;QRT(0.149)S(0.8)GS(0.051)GFHR 63.966 0.024941 3310600.0 4627.4 3489.9 10357.900000000001 15674.400000000001 11759.099999999999 9956.1 10214.7 17739.6 8188.7 13261.0 True False 6098.816944100721 4617.941926285876 10220.547478268367 12060.909247065956 10126.551941840948 9333.543493110068 11123.788511504068 14998.352435454422 8621.537964437617 12796.736426334255 0.47659158873898794 0.3608687224957347 0.798683909534592 0.9424988407392647 0.7913386354509603 0.7293690502136684 0.8692676117492389 1.172045116486848 0.673729432036707 1.0 13.643488303690324 -5.339266126704675 4.472955364429898 0.8779064626605947 0.41809814018717906 0.6417453473931662 0.13629401804217484 0.12504623778973054 4.600696509211044 0.03598945081406742 0.08064333261712359 4.57861232810097e-06 5.339266126704675 -0.45980832247341563 QRVEQFAR ddPTM_PC-9_Lapatinib_30min_R1 1 QRVEQFAR 8 1 P34897-3;P34897-2;P34897 P34897-3 SHMT2 Serine hydroxymethyltransferase, mitochondrial 0 98.58200000000001 0.013040000000000001 0.0 10127.0 7618.8 6564.0 7712.2 7063.1 5698.0 6031.2 5982.4 5884.3 6193.4 False True 9982.58712293565 7601.159136697678 6024.33325777274 8279.380915145013 6647.662344588881 5454.3098226867505 6343.466025111756 6260.36414382493 5221.548169573994 7263.92093781324 1.374269792911712 1.046426468813682 0.8293500589209785 1.1397950206266247 0.9151617152086075 0.7508768156180865 0.8732840127829665 0.8618436513035032 0.7188332877348069 1.0 12.826532784751612 -1.5228787455217743 0.7026135427197221 0.8591365573359222 64.64099754989732 0.6321273442653885 0.11352400755293603 189.9266334015215 0.9975444088673078 0.04539177572949772 19038.73940566968 0.029999999983322142 1.5228787455217743 63.7818609925614 QRWDEAFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QRWDEAFR 8 1 H7C4A8;G3V5Q1;G3V3M6;P27695 H7C4A8 APEX1 DNA-(apurinic or apyrimidinic site) lyase;DNA-(apurinic or apyrimidinic site) lyase, mitochondrial 0 88.37 0.026266 0.0 4050.8 4679.0 8830.6 6698.8 6820.2 6406.3 6026.9 4123.9 5762.1 4388.2 False True 4736.52043305309 5143.500197566271 9041.154994236991 6323.487953802626 5483.830769215349 6070.342350353392 5455.988401022628 4015.65199463323 5846.359811677781 5183.745923027914 0.9137254223845924 0.9922361693533516 1.7441354434585983 1.2198684209639985 1.0578895745747028 1.1710339280686817 1.0525184841304283 0.7746621949186159 1.1278253021056293 1.0 12.339779292126389 -7.125947465110353 1.5468573116425635 0.9611923376017552 1.2154750971310062 0.15009300641457357 0.2260060855262842 0.7412660279446821 3.5184561930637432 0.12755705400050793 0.0856780008119743 7.482600090973002e-08 7.125947465110353 0.25428275952925106 QRWDEAFR ddPTM_PC-9_Lapatinib_30min_R1 1 QRWDEAFR 8 1 H7C4A8;G3V5Q1;G3V3M6;P27695 H7C4A8 APEX1 DNA-(apurinic or apyrimidinic site) lyase;DNA-(apurinic or apyrimidinic site) lyase, mitochondrial 0 101.25 0.0060182 1795500.0 5711.1 7789.6 8187.1 6742.9 5999.2 6748.0 6874.4 6526.2 7347.0 4878.5 False True 5629.658666712528 7771.563659791599 7513.98824111992 7238.795359655002 5646.338850881006 6459.403770356303 7230.32279530247 6829.431077064431 6519.503492660156 5721.742224807362 0.9839063777295676 1.3582512728547904 1.3132343167334664 1.2651383224274344 0.9868216059088725 1.1289225408216945 1.263657555902197 1.1935929317917433 1.1394262859997424 1.0 12.482238787676355 QS(ph)ARKPLLGLPSYMLQS(ph)EELRASLLAR ddPTM_PC-9_Lapatinib_30min_R1 1 QSARKPLLGLPSYMLQSEELRASLLAR 27 3 Q6XZF7;A0A1C7CYY6;A0A1B0GTX1;Q6XZF7-2 Q6XZF7 DNMBP Dynamin-binding protein 2 QS(0.902)ARKPLLGLPS(0.096)Y(0.007)MLQS(0.979)EELRAS(0.017)LLAR 49.902 0.027308999999999996 0.0 13301.0 14038.0 12693.0 10901.0 17472.0 20382.0 20796.0 21061.0 24507.0 19044.0 True False 13111.325300895338 14005.495873492144 11649.430536396914 11702.695904669983 16444.33131127365 19510.309372762596 21872.715124390517 22039.570946960557 21746.763589849244 22335.730025465073 0.5870112723401946 0.6270444645204974 0.5215603216512441 0.5239450822215206 0.7362343336226481 0.8735022025480609 0.9792702141122466 0.9867405686688161 0.9736311983112106 1.0 14.447065788294331 -6.694507024287396 1.830614111604562 0.982692490294478 0.5654964271979173 0.9667064436551545 0.03519208046112614 0.0600886419961514 0.41514014095574425 0.01532413523077257 0.014721040862626697 2.020658749554045e-07 6.694507024287396 -0.41719606309656077 QS(ph)EKPHSTPPQSCTSDLSK ddPTM_PC-9_AZD4547_30min_R2 1 QSEKPHSTPPQSCTSDLSK 19 1 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 QS(0.369)EKPHS(0.313)T(0.313)PPQS(0.005)CT(0.001)SDLSK 48.111999999999995 0.031476 9596900.0 15453.0 13348.0 45176.0 77806.0 67271.0 50017.0 34939.0 63101.0 44322.0 55295.0 True False 20366.73255763247 17662.47996563335 44576.93672252599 59869.028790716904 57931.58283198395 46889.42908316372 38048.50331418842 53350.19036672805 46664.77043484363 53359.138880488106 0.3816915524676879 0.33101133819256606 0.8354133454508669 1.1220014049478837 1.0856918617396927 0.8787516078208268 0.7130644180635691 0.9998322965110045 0.8745412953413981 1.0 15.703447763784206 -5.3241946353561955 4.145729255748415 0.9471809200182372 0.350721110089863 0.8156607529022004 0.11161479894038091 0.08810913009347711 3.03073299971767 0.0323335829439257 0.07507553995585615 4.74029494471357e-06 5.3241946353561955 -0.5964598099283742 down QS(ph)EKPHSTPPQSCTSDLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSEKPHSTPPQSCTSDLSK 19 1 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 QS(0.392)EKPHS(0.281)T(0.281)PPQS(0.046)CTSDLSK 61.136 0.0076515 6048200.0 31920.0 38396.0 76493.0 82904.0 108320.0 103250.0 88915.0 78500.0 83252.0 72452.0 True False 37323.425551262604 42207.701129676134 78316.88322131798 78259.15765839453 87095.47358162636 97835.38823876309 80492.32751114614 76439.45817762522 84469.4030026898 85586.9740702837 0.43608768690213007 0.49315566519521215 0.9150561060495545 0.9143816393617141 1.0176253399273572 1.1431107280229469 0.9404740427561575 0.8931202324649709 0.9869422762081043 1.0 16.38510362157082 -5.271521145957048 2.691448579492642 0.9855890784001647 0.42877977716807103 0.909719921325301 0.06490290903491804 0.08107437273024588 1.1416951205409396 0.019529276466206794 0.06059799102021586 5.351540962883834e-06 5.271521145957048 -0.5568093012320937 down QS(ph)GDGQESTEPVENK ddPTM_PC-9_AZD4547_30min_R2 2 QSGDGQESTEPVENK 15 0 O15234;J3KSY7 O15234 CASC3 Protein CASC3 1 QS(0.93)GDGQES(0.035)T(0.035)EPVENK;QS(0.987)GDGQES(0.008)T(0.005)EPVENK 189.77 1.8584e-07 16060800.0 54800.0 64030.0 62428.0 51502.0 53983.0 75451.0 73297.0 81839.0 76444.0 70268.0 True False 72225.26008919036 84726.44532510503 61600.163930269446 39629.00959796808 46488.39226440798 70733.0370424814 79820.29100489606 69192.66302313197 80484.67377648094 67807.93870791476 1.0651446049746973 1.2495062811165427 0.9084506195596723 0.5844302356494204 0.6855892267225299 1.043137992251418 1.177152594900797 1.0204212713378882 1.1869506035741875 1.0 16.049166568310298 -6.983467864868875 24.890220161722475 1.0995918470057888 0.8975238286557186 0.21603821503116116 0.18024577047490759 407.44203292824375 613428.6736201042 0.07273362645434484 0.0641290591155297 1.0388004644494896e-07 6.983467864868875 -0.20206801835007027 QS(ph)GDGQESTEPVENK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSGDGQESTEPVENK 15 0 O15234;J3KSY7 O15234 CASC3 Protein CASC3 1 QS(1)GDGQESTEPVENK 195.45 1.2024000000000001e-09 6092400.0 30773.0 47057.0 37678.0 31644.0 33763.0 27581.0 34026.0 25429.0 24304.0 23189.0 True False 35982.26110554524 51728.50797112118 38576.38641461072 29871.089271232206 27147.38251972345 26134.60380642443 30802.81095309297 24761.515694252623 24659.400021349316 27392.982135977018 1.313557645054182 1.8883854161749956 1.4082580064893992 1.0904650367365636 0.9910342139809961 0.9540620176618202 1.1244781893475408 0.9039364743618653 0.9002086701966813 1.0 14.741518713084206 -5.709647371359301 2.8189092831218288 0.9850006247104516 1.6112232293041855 0.7566507516943828 0.14394083238413358 0.11181376701059025 1.8012287799522246 0.039252394867737385 0.07263602706666085 1.951428433525761e-06 5.709647371359301 0.6262226045937339 QS(ph)GDGQESTEPVENK ddPTM_PC-9_Lapatinib_30min_R1 2 QSGDGQESTEPVENK 15 0 O15234;J3KSY7 O15234 CASC3 Protein CASC3 1 QS(0.485)GDGQES(0.169)T(0.347)EPVENK;QS(0.805)GDGQES(0.098)T(0.098)EPVENK 129.36 1.5358e-05 16007000.0 23704.5 47842.0 40337.0 41212.0 50596.0 41227.0 56908.0 54751.0 44683.0 46391.0 True False 23366.469483127094 47731.224788403706 37020.647565322804 44242.86795920183 47620.04275556326 39463.81731483093 59854.41778701746 57294.9313383523 39650.33000715036 54409.62253787808 0.42945472497737275 0.8772570468610564 0.6804062560726335 0.8131441810389604 0.8752136209438294 0.7253095219941582 1.1000704470123626 1.053029384617869 0.728737457782347 1.0 15.731574199407968 -4.0807079555234465 0.40266081587512803 0.958213492379568 6.608551102506226e-14 0.4610169295405341 0.13932324811705882 9.612943888717982 0.7965285434425641 0.10801529565461067 4.961086962818029 8.304089943570736e-05 4.0807079555234465 -0.9582134923795019 QS(ph)LGELIGTLNAAK ddPTM_PC-9_AZD4547_30min_R2 3 QSLGELIGTLNAAK 14 0 P60174;P60174-3 P60174 TPI1 Triosephosphate isomerase 1 QS(1)LGELIGTLNAAK;QS(0.999)LGELIGT(0.001)LNAAK;QS(1)LGELIGTLNAAK 207.16 6.4382e-13 51209000.0 189907.5 196603.9 212736.4 224199.1 189037.9 214492.2 223740.7 261372.5 201859.7 190763.1 True False 250294.13467861153 260152.2658761902 209915.3763365055 172513.4613365657 162793.25061667452 201079.9688264343 243653.1888568315 220983.3858675394 212529.5916372548 184084.54193276903 1.3596694869144603 1.4132216814337537 1.1403204969441179 0.9371425733268288 0.884339602377529 1.0923240306612616 1.323593965569461 1.2004450973849095 1.1545216638281035 1.0 17.490008959281838 -5.319860220556549 4.898753291276897 1.091761429582575 1.387303579042767 0.48827739692565686 0.1213453956396053 0.18751297642170153 9.455456405247457 0.0369698236166612 0.08231385187438932 4.787841661557436e-06 5.319860220556549 0.29554214946019197 QS(ph)LGELIGTLNAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSLGELIGTLNAAK 14 0 P60174;P60174-3 P60174 TPI1 Triosephosphate isomerase 1 QS(1)LGELIGTLNAAK 85.28 0.006956100000000001 1345800.0 4454.2 6652.6 5672.2 5330.0 6941.2 5164.1 5422.1 4881.8 3733.8 3900.8 True False 5208.208085539905 7313.026162498267 5807.44675993829 5031.377380093149 5581.121687821117 4893.285505121511 4908.479435395444 4753.657922694656 3788.3997613443876 4607.984161284188 1.1302573757303112 1.587033702056002 1.2603009378226304 1.0918825247634893 1.2111850849473682 1.0619145669454326 1.0652118721752533 1.0316133381347974 0.8221381907459958 1.0 12.169920042571647 -6.429632665636699 0.6001256320311277 0.9404321454644059 1.3814670599882883 0.5422785636976255 0.12906818781278112 0.6845405905030065 0.5325277061449385 0.09541639303984971 0.15456218794672386 3.7184961345263213e-07 6.429632665636699 0.44103491452388244 QS(ph)LGELIGTLNAAK ddPTM_PC-9_Lapatinib_30min_R1 2 QSLGELIGTLNAAK 14 0 P60174;P60174-3 P60174 TPI1 Triosephosphate isomerase 1 QS(1)LGELIGTLNAAK;QS(1)LGELIGTLNAAK 220.1 8.696e-16 79616000.0 154222.0 248558.0 260110.0 218971.0 288440.0 268550.0 250800.0 276870.0 214931.0 222531.0 True False 152022.76599914886 247982.47922235797 238724.75985363597 235074.8578058423 271474.52629485895 257064.74252062605 263785.19682617515 289734.3909636286 190723.20745623249 260995.18684608102 0.5824734464885077 0.9501419632255627 0.9146711199483584 0.9006865630226164 1.0401514662987177 0.9849405486248568 1.0106898905447612 1.1101139238038753 0.7307537344307784 1.0 17.993663675954892 -4.759290570716444 5.34908277887369 0.9665186361183232 0.5614922917911395 0.582283016271837 0.09595242928653087 0.11075536412618596 9.457646577978576 0.023102781587145946 0.16726891856058193 1.7406418832356142e-05 4.759290570716444 -0.40502634432718376 QS(ph)LGHPPPEPGPDR ddPTM_PC-9_AZD4547_30min_R2 1 QSLGHPPPEPGPDR 14 0 P13861-2;P13861;C9J830 P13861-2 PRKAR2A cAMP-dependent protein kinase type II-alpha regulatory subunit 1 QS(1)LGHPPPEPGPDR 81.65100000000001 0.045959 0.0 5245.2 8799.4 10534.0 19968.0 18600.0 18251.0 13580.0 18480.0 13694.0 16090.0 True False 6913.064493062437 11643.633968354368 10394.312277206676 15364.686102524687 16017.711059370333 17109.76208482758 14788.593692054115 15624.34062815383 14417.836883144912 15526.693997414834 0.44523737598058216 0.7499107002619496 0.6694478733809857 0.9895658473776117 1.0316240573838353 1.101957833887647 0.9524624942383993 1.0062889518370912 0.9285838238034095 1.0 13.922463057872573 -5.4000983320589935 1.196640122290049 1.0122819015683266 0.4908516918076187 0.8237428678103491 0.08096625733855876 0.2633378774110286 0.610679724936921 0.026580314620192863 0.13072039044284248 3.980170421544756e-06 5.4000983320589935 -0.521430209760708 down QS(ph)LSPMSQRPVLK ddPTM_PC-9_Lapatinib_30min_R1 1 QSLSPMSQRPVLK 13 1 Q9NSV4-1;Q9NSV4-7;Q9NSV4-6;Q9NSV4-5;Q9NSV4-4;Q9NSV4 Q9NSV4-1 DIAPH3 Protein diaphanous homolog 3 1 QS(0.768)LS(0.229)PMS(0.004)QRPVLK 83.87700000000001 0.042957 10005000.0 15969.0 11118.0 14531.0 11881.0 13624.0 12024.0 11284.0 9783.1 14253.0 7580.5 True False 15741.27913164405 11092.256954087885 13336.31727128209 12754.768373854136 12822.663105814578 11509.761549312998 11868.23030696396 10237.658540962431 12647.677049256183 8890.779324618668 1.7705173592663885 1.2476135723415493 1.5000166784427635 1.4346063385620245 1.4422428718153513 1.2945728522855513 1.3348920126833759 1.1514916934912824 1.4225611262484743 1.0 13.118094169238445 -1.5228787452991237 0.038542118004580204 6.785526554142341e-10 3.542130422347689 0.5505437033455114 0.13324072832301717 627.8649466196357 1.8517067284442996 47.725167751350156 148.18021889503476 0.0299999999987023 1.5228787452991237 3.5421304216691363 QS(ph)PASPPPLGGGAPVR ddPTM_PC-9_AZD4547_30min_R2 1 QSPASPPPLGGGAPVR 16 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 QS(0.934)PAS(0.066)PPPLGGGAPVR 97.734 0.0021474 39303000.0 13465.0 19433.0 25130.0 26142.0 24491.0 18052.0 15910.0 25885.0 18263.0 15065.0 True False 17746.589910601255 25714.3372169728 24796.759780349705 20115.36578987381 21090.847395432196 16923.205586286087 17325.95917824603 21885.068028125654 19228.34489534653 14537.578935429128 1.220739023287539 1.7688184071905608 1.705700783499666 1.3836805894034536 1.4507812813337357 1.1641006842647654 1.1918049941604387 1.5054135303637226 1.3226648660517788 1.0 13.827499404743591 -6.255606202347942 1.9040901488905737 1.2723038298141658 1.57379155820598 0.32288319463472226 0.18985855886699823 0.4176232613836561 2.977761035057326 0.06586050748574972 0.0867422055147371 5.551288493426239e-07 6.255606202347942 0.30148772839181426 QS(ph)PASPPPLGGGAPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QSPASPPPLGGGAPVR 16 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 QS(0.985)PAS(0.015)PPPLGGGAPVR;QS(1)PASPPPLGGGAPVR;QS(0.547)PAS(0.453)PPPLGGGAPVR 176.42 9.9529e-06 42071100.0 46555.0 51356.0 48245.0 51794.0 102227.0 53198.0 59931.0 60514.0 60220.0 53355.0 True False 54435.84199683677 56454.28428001994 49395.34377018141 48892.15009841364 82196.3531926598 50408.203230273306 54253.90181713438 58925.571619882896 61100.60357495292 63027.839142052406 0.8636793318290517 0.8957039468350334 0.7837067626395057 0.7757230894148268 1.3041277364341384 0.7997767957213809 0.8607926680598507 0.9349134036957256 0.9694224711915654 1.0 15.943701581509167 QS(ph)PAY(ph)MKEDVKALDTTKAPK ddPTM_PC-9_Lapatinib_30min_R1 1 QSPAYMKEDVKALDTTKAPK 20 3 A0A0A0MSL2;A0A0A0MT14;B4DWF2;Q9UKS7-8;Q9UKS7-4;Q9UKS7-7;Q9UKS7-2;Q9UKS7 A0A0A0MSL2 IKZF2;ZNFN1A2 Zinc finger protein Helios 2 QS(1)PAY(1)MKEDVKALDTTKAPK 50.851000000000006 0.037436000000000004 0.0 5111.3 5678.1 8283.0 2877.2 6916.1 8576.4 3050.8 7418.8 9390.1 6922.8 True False 5038.411924702378 5664.952708311425 7602.003713304633 3088.7988860578366 6509.308595575764 8209.607364564874 3208.7554963209573 7763.504531660936 8332.488055863361 8119.396755948838 0.6205401800338043 0.6977061078042386 0.9362769109336692 0.3804222134846122 0.8016985487014894 1.0111105062762133 0.3951962926272815 0.9561676519838557 1.0262447206756335 1.0 12.987156828632841 -7.971756433975343 24.998359579643697 1.0058172414432367 0.7038367093112405 0.3456222548094604 0.19112965087468076 225.91449132785291 199956.5995928058 0.10199864549119927 0.04899730922756138 1.0671944697008439e-08 7.971756433975343 -0.30198053213199616 QS(ph)PCHSPR ddPTM_PC-9_AZD4547_30min_R2 1 QSPCHSPR 8 0 H3BRS1;Q12968;I3L3K7;H3BR83;Q12968-5;Q12968-6;Q12968-4;Q12968-3;Q12968-2 H3BRS1 NFATC3 Nuclear factor of activated T-cells, cytoplasmic 3 1 QS(0.999)PCHS(0.001)PR 86.014 0.012794 572380.0 3331.6 1123.3 2637.5 3559.8 4336.8 3062.2 3318.8 3925.4 3755.8 4351.2 True False 4390.979498415084 1486.3847576712578 2602.525026688113 2739.143108361749 3734.7101786170574 2870.7201499183047 3614.16677063249 3318.8196267183484 3954.323920382333 4198.865812402202 1.0457537093577591 0.35399672770702 0.619816193935283 0.6523530950360771 0.8894569022867636 0.6836894242819216 0.8607483382672805 0.790408594843765 0.941760012597315 1.0 12.035783967839716 -7.623463874024265 0.516992064695905 0.9966150908561765 0.6462186826040459 0.2578404759563302 0.17151239850855665 1.1430861555013534 0.6794251124447435 0.16671886547331713 0.11746998071748443 2.3797762499680564e-08 7.623463874024265 -0.3503964082521306 QS(ph)PCHSPR ddPTM_PC-9_Lapatinib_30min_R1 1 QSPCHSPR 8 0 H3BRS1;Q12968;I3L3K7;H3BR83;Q12968-5;Q12968-6;Q12968-4;Q12968-3;Q12968-2 H3BRS1 NFATC3 Nuclear factor of activated T-cells, cytoplasmic 3 1 QS(0.958)PCHS(0.042)PR 75.695 0.026007 778920.0 2592.0 3132.9 3278.5 2345.7 2483.8 1967.5 2951.7 3373.5 4381.8 2954.8 True False 2555.0376046854144 3125.6459625348007 3008.954385375978 2518.2106030258105 2337.707767338685 1883.3546114665112 3104.524583220979 3530.2451255672295 3888.275541600418 3465.5332429764862 0.737271128437059 0.9019235261613701 0.8682514852437656 0.7266444805079877 0.6745593256323429 0.5434530502004161 0.8958288279337228 1.0186729943283312 1.1219847766518165 1.0 11.758861642163954 -7.604703985195389 3.5688929840902426 1.0529372850558436 0.7491729927795174 0.6569892480557922 0.09847597047566825 0.1623039559826972 4.0840551479525695 0.0567802527174506 0.030847065646546178 2.4848261839584e-08 7.604703985195389 -0.3037642922763262 QS(ph)PDHPTVGAGVLHITENGPTEVDYSPSDMQDSSLSHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSPDHPTVGAGVLHITENGPTEVDYSPSDMQDSSLSHK 38 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QS(0.68)PDHPT(0.26)VGAGVLHIT(0.044)ENGPT(0.01)EVDY(0.003)S(0.003)PSDMQDSSLSHK 47.534 0.002163 6471700.0 3853.2 12214.0 18213.0 17612.0 25354.0 20829.0 20620.0 11218.0 17981.0 11808.0 True False 4505.470655830983 13426.525200486105 18647.266993187135 16625.256738874406 20386.065705211873 19736.690572641106 18666.724324127925 10923.539386453496 18243.938108290076 13948.696927923429 0.32300297863749783 0.9625648381253444 1.3368465233378035 1.1918860109142426 1.4615032365067515 1.4149486991240656 1.33824144438608 0.7831225700076707 1.3079313574996492 1.0 13.767842732899194 -4.805705376679296 2.590509350138412 1.2382693209452789 0.15959705702834193 0.6668604384011534 0.19367837789071787 0.2799220306642106 2.5583858319233737 0.05222163447589089 0.6557562277701124 1.564208434379615e-05 4.805705376679296 -1.0786722639169368 QS(ph)PDHPTVGAGVLHITENGPTEVDYSPSDMQDSSLSHK ddPTM_PC-9_Lapatinib_30min_R1 1 QSPDHPTVGAGVLHITENGPTEVDYSPSDMQDSSLSHK 38 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QS(0.902)PDHPT(0.093)VGAGVLHIT(0.002)ENGPT(0.002)EVDY(0.001)SPSDMQDSSLSHK 66.1 1.5726e-06 23213000.0 27911.0 25294.0 88152.0 37998.0 74162.0 88170.0 42012.0 54454.0 108000.0 39246.0 True False 27512.984021749475 25235.433297058727 80904.48283656048 40792.49967761213 69799.93696810195 84399.17463430871 44187.17579370526 56984.13163410051 95835.90270958164 46029.618807992134 0.5977234818414874 0.5482433691733526 1.757661369607367 0.8862228437687892 1.5164135349298735 1.8335840447945326 0.9599726640802211 1.2379883455434209 2.0820485850502335 1.0 15.49027487455321 -5.246683125453278 24.87975536871777 1.4019948388208858 0.5729832318360891 0.43726063096714696 0.37940206162367945 683.9250896094179 1153125.7647241028 0.0938148607336133 0.24591739133802523 5.666525853132499e-06 5.246683125453278 -0.8290116069847967 QS(ph)PECENFLDVGLGR ddPTM_PC-9_AZD4547_30min_R2 1 QSPECENFLDVGLGR 15 0 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36;H0YMW2;A0A087X047 Q12802-2 AKAP13 A-kinase anchor protein 13 1 QS(1)PECENFLDVGLGR 83.25200000000001 0.0069623 2450700.0 6020.7 4789.4 6242.9 7794.8 5833.8 7166.1 6477.6 7568.7 6039.5 4758.5 True False 7935.15736166038 6337.4798881783345 6160.1150669616045 5997.829288459502 5023.877568717989 6718.002634161573 7054.09385122605 6399.131326423589 6358.735640116377 4591.906363374677 1.7280747327409973 1.3801413588757945 1.341515827956566 1.3061741276561192 1.0940723026908257 1.4630095003122816 1.5362015888411682 1.3935674685057706 1.384770319106251 1.0 12.16487750801882 -4.752222126484181 3.5960281623237713 1.3349163122904943 1.7873782205043107 0.3888532081749335 0.15294599361643846 0.35279916242106607 7.373587782693344 0.03881381780873454 0.4515606961598281 1.7692038407945135e-05 4.752222126484181 0.4524619082138164 QS(ph)PGPALAR ddPTM_PC-9_AZD4547_30min_R2 3 QSPGPALAR 9 0 P85037 P85037 FOXK1 Forkhead box protein K1 1 QS(1)PGPALAR;QS(1)PGPALAR;QS(1)PGPALAR 98.182 0.0045443 146215000.0 117357.0 119072.0 172438.0 201732.0 171455.0 151338.0 151397.0 180079.0 148942.0 164213.0 True False 154674.08482275758 157559.69542013007 170151.35945101237 155225.80412833087 147651.4327787277 141874.81093603824 164871.0397051487 152251.92835375038 156814.7700488807 158463.95285254743 0.9760837214926957 0.9942936080027059 1.0737543547796022 0.9795653922174358 0.931766689652877 0.8953128353932608 1.0404324563237617 0.9607985009399745 0.9895926942753894 1.0 17.273795169972253 -5.9827490358548685 24.99417937119801 0.9664356917312024 1.0150007108639043 0.1760345328170888 0.04338872651898877 402.00551945807115 582444.0270278094 0.012581550851213142 0.018657299920569456 1.040521274310456e-06 5.9827490358548685 0.04856501913270195 QS(ph)PGPALAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QSPGPALAR 9 0 P85037 P85037 FOXK1 Forkhead box protein K1 1 QS(1)PGPALAR;QS(1)PGPALAR;QS(1)PGPALAR;QS(1)PGPALAR 100.09 0.0039328 137780000.0 307938.0 268672.0 308599.0 338256.0 367316.0 303933.0 314497.0 342079.0 298637.0 240947.0 True False 360065.821347265 295343.98056861025 315957.1705282243 319304.6129607479 295343.0665999681 287994.218436532 284705.5673988976 333099.78871265997 303004.0011593033 284628.7837645976 1.265036573549981 1.0376462164588198 1.110067528481367 1.1218282590309945 1.0376430053688166 1.0118239435499883 1.0002697676365842 1.170295513710765 1.064558535337392 1.0 18.11872203965558 -4.7564404962392475 24.99649718692558 1.0660726924183817 1.265036879689151 0.5597254265479437 0.05400351023837532 123.92545128010555 619608.1647125166 0.013838682457493527 0.11178250715591463 1.7521024776562282e-05 4.7564404962392475 0.19896418727076925 QS(ph)PGPALAR ddPTM_PC-9_Lapatinib_30min_R1 4 QSPGPALAR 9 0 P85037 P85037 FOXK1 Forkhead box protein K1 1 QS(1)PGPALAR;QS(1)PGPALAR;QS(1)PGPALAR;QS(1)PGPALAR 123.62 0.0014850999999999998 139242000.0 238856.0 258150.0 322952.0 261000.0 260102.0 264213.0 229993.0 244704.0 248415.0 222548.0 True False 235449.86963917376 257552.26953568863 296400.13319077087 280194.8106704766 244803.31174020702 252913.22590058506 241900.91217560816 256073.8411758714 220435.88677408092 261015.12527343008 0.9020545050503297 0.9867331223272449 1.1355668867092386 1.0734811263406845 0.9378893712912608 0.9689600387550041 0.9267697108441568 0.9810689740972584 0.8445329999292577 1.0 17.99377388477493 -6.279007582391615 23.82538672609787 0.9427230886194623 1.029700493710607 0.2523292234341634 0.06828083996732763 631.9703705791908 857053.0340841016 0.022097951492308872 0.02512233734263862 5.2600808268182e-07 6.279007582391615 0.0869774050911446 QS(ph)PLTYEDHGAPFAGHLPR ddPTM_PC-9_AZD4547_30min_R2 2 QSPLTYEDHGAPFAGHLPR 19 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 QS(0.922)PLT(0.044)Y(0.034)EDHGAPFAGHLPR;QS(0.999)PLT(0.001)YEDHGAPFAGHLPR 140.67 0.00015465 9399500.0 40150.0 32826.8 50894.0 56173.0 55445.0 52253.0 39527.8 59467.0 41453.4 46881.0 True False 52916.864828120335 43437.42113693836 50219.112306451134 43223.182714198665 47747.41880036496 48985.6116496902 43045.69762450489 50277.7415657156 43644.542095206634 45239.71045946582 1.1696994585218032 0.9601613426738819 1.1100670582639292 0.9554257150457685 1.055431573620393 1.0828011751662439 0.9515025005094421 1.11136302719629 0.9647396424942101 1.0 15.46530207545478 -4.744041088244495 24.8944357975758 1.0262833531299678 1.1696999164745132 0.3416761288757235 0.0614537999115964 1158.4054889406616 1657417.7649290455 0.013870733645794974 0.4112305135846777 1.802847166899951e-05 4.744041088244495 0.14341656334454544 QS(ph)PLTYEDHGAPFAGHLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSPLTYEDHGAPFAGHLPR 19 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 QS(0.968)PLT(0.031)YEDHGAPFAGHLPR;QS(0.711)PLT(0.22)Y(0.069)EDHGAPFAGHLPR 119.18 4.4546000000000003e-05 10969900.0 31010.0 26094.0 32357.0 25548.0 28456.0 20555.1 31870.0 28401.0 17956.3 23875.0 True False 36259.38052458187 28684.43987076178 33128.51359460584 24116.62838773355 22880.251073105184 19477.1543708145 28851.04288118124 27655.503843346913 18218.876917517875 28203.34850560397 1.2856409768995045 1.0170579520038983 1.1746305084314101 0.8550980527344689 0.8112600909271077 0.6905972305715548 1.0229651587451956 0.9805751908448671 0.6459827603058483 1.0 14.783578839536633 -5.765037779139697 24.768120045825523 0.8552013415123302 1.1449046642728677 0.5205711582371759 0.13216007677907457 65.74158694555057 452511.0342398408 0.036646552471017835 0.056870071936819415 1.7177589533497265e-06 5.765037779139697 0.28970332276053756 QS(ph)PLTYEDHGAPFAGHLPR ddPTM_PC-9_Lapatinib_30min_R1 1 QSPLTYEDHGAPFAGHLPR 19 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 QS(0.669)PLT(0.321)Y(0.01)EDHGAPFAGHLPR 79.69 0.0023381 4510200.0 8769.5 10326.0 9214.8 5911.8 11366.0 9849.7 8635.2 9386.8 10039.0 9466.0 True False 8644.445321870657 10302.090781427554 8457.194714156649 6346.573493186676 10697.474226415767 9428.451291772146 9082.288403641905 9822.944996198152 8908.302104643435 11102.185487347844 0.7786255536553545 0.92793358507367 0.7617594503167461 0.5716508250037159 0.9635467033591458 0.849242818228618 0.818063111447036 0.8847757954857153 0.802391755640853 1.0 13.438556081476356 QS(ph)PNSSSAAASVASR ddPTM_PC-9_AZD4547_30min_R2 2 QSPNSSSAAASVASR 15 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 QS(0.997)PNS(0.001)SS(0.001)AAASVASR;QS(1)PNSSSAAASVASR 137.32 4.052e-05 15412300.0 9015.5 11424.2 13211.0 11009.3 11757.4 14132.3 11287.599999999999 16346.300000000001 13229.3 11471.2 True False 11882.241465950661 15116.849237592802 13035.813508085943 8471.275976989435 10125.087957496813 13248.60504692393 12292.17453302136 13820.354935605576 13928.573789848773 11069.596779561545 1.0734123114483765 1.3656187789517265 1.1776231571645628 0.7652741238624388 0.9146754086103086 1.1968462185890654 1.1104446510388828 1.2484966897008316 1.25827291338795 1.0 13.434315051106879 -9.543804308111682 14.443329051894846 1.0000202770156488 1.1209109348876543 0.047226792342500046 0.16594791555609092 0.0 0.0 0.1763483265948526 0.04277075161479397 2.858878455886693e-10 9.543804308111682 0.12089065787200548 QS(ph)PNSSSAAASVASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QSPNSSSAAASVASR 15 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 QS(0.949)PNS(0.034)S(0.011)S(0.006)AAASVASR;QS(0.993)PNS(0.006)S(0.001)SAAAS(0.001)VASR;QS(0.983)PNS(0.009)S(0.003)S(0.005)AAASVASR 127.91 1.9441e-05 19395200.0 21907.0 39500.0 34115.0 23862.6 32553.2 21536.6 25847.0 17475.9 18781.100000000002 17526.9 True False 25615.422417027232 43421.29895359428 34928.430981857964 22525.65588559301 26174.634145101503 20407.182782982505 23398.58504392503 17017.176142246622 19055.73805714958 20704.388227135943 1.2371977445561373 2.097202702984709 1.6870061843256716 1.0879652969446372 1.264207078130232 0.9856452921529016 1.1301268497881996 0.8219115655850809 0.9203719447346153 1.0 14.337648954161779 -5.771671695407206 4.718245906913431 1.0295705220450886 1.7245123846058146 0.6345700178288409 0.22348926337426375 0.11047156669704657 6.240862449273602 0.0619880898550988 0.10091318149035594 1.6917193023476767e-06 5.771671695407206 0.694941862560726 QS(ph)PNSSSAAASVASR ddPTM_PC-9_Lapatinib_30min_R1 3 QSPNSSSAAASVASR 15 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 QS(0.927)PNS(0.028)S(0.015)S(0.028)AAAS(0.002)VASR;QS(0.927)PNS(0.048)S(0.012)S(0.012)AAASVASR;QS(1)PNSSSAAASVASR 172.95 8.5722e-05 29797500.0 17006.100000000002 27097.9 21902.5 19570.9 30836.0 27288.9 27149.2 30220.5 24171.300000000003 21730.6 True False 16763.58989546321 27035.15647744001 20101.760996094967 21010.209272608547 29022.28710590857 26121.817360532907 28554.852733944157 31624.65475535927 21448.873658926957 25486.705255795594 0.6577386024288575 1.0607552528309756 0.7887155595179919 0.8243595655751107 1.138722593392451 1.0249193490630921 1.1203822717513037 1.2408294613980333 0.8415710639589067 1.0 14.63745726337057 -6.254801423672025 24.827067499677774 1.0742702661234869 0.8460126844429435 0.40446198938749467 0.13469826246241617 481.13818245853975 1799536.2430181096 0.03836181546661841 0.048357143209585764 5.561584964369868e-07 6.254801423672025 -0.22825758168054333 QS(ph)PPISTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSPPISTSK 9 0 P33981-2;P33981 P33981-2 TTK Dual specificity protein kinase TTK 1 QS(0.858)PPIS(0.134)T(0.006)S(0.001)K;QS(0.894)PPIS(0.087)T(0.017)S(0.002)K 91.12299999999999 0.0080442 7483400.0 74596.0 106287.0 89801.0 71657.0 90269.0 70087.0 95341.0 81803.0 70472.0 58511.0 True False 87223.62946184163 116838.47093368795 91942.1964121892 67642.2906051286 72581.43745143857 66411.51433888801 86309.61027093489 79655.75792744278 71502.51968007446 69118.58112717888 1.261941840231779 1.6904060967152086 1.3302095458674799 0.9786411917320192 1.0501002229471117 0.960834456608566 1.2487179114994322 1.1524507104808097 1.0344905597600318 1.0 16.0767859815735 -5.583994726487071 4.887262375796794 1.072117355445405 1.4851875916087576 0.6492226627527725 0.12611877682967446 0.11103270703584178 5.308600908224122 0.03380561520264875 0.061025205234154424 2.6061851959636866e-06 5.583994726487071 0.4130702361633525 QS(ph)PPISTSK ddPTM_PC-9_Lapatinib_30min_R1 2 QSPPISTSK 9 0 P33981-2;P33981 P33981-2 TTK Dual specificity protein kinase TTK 1 QS(0.999)PPIS(0.001)TSK;QS(1)PPISTSK 128.36 0.0013325 25855000.0 137949.0 220650.0 231330.0 224800.0 281140.0 282200.0 280980.0 267220.0 277020.0 242580.0 True False 135981.82196325148 220139.0984816958 212310.94035962285 241332.54191081642 264603.8979425064 270130.96384033025 295527.7695543009 279636.0167345717 245819.0904500767 284509.6297824679 0.4779515620164466 0.7737492001589229 0.7462346371964732 0.8482403287907545 0.9300349451961217 0.9494615842945935 1.0387267727291245 0.9828701297329637 0.8640097371678651 1.0 18.118117958618207 -4.381635882206747 0.5731541314828456 0.9766686124268189 8.893501163358018e-14 0.859901191281545 0.0587102474674818 2.0875038733948164 0.37375395072129874 0.03071126638789158 1.49456370185076 4.153020910509566e-05 4.381635882206747 -0.97666861242673 down QS(ph)PSFK ddPTM_PC-9_Lapatinib_30min_R1 1 QSPSFK 6 0 Q6IN85-4;Q6IN85-2;Q6IN85 Q6IN85-4 SMEK1 Serine/threonine-protein phosphatase 4 regulatory subunit 3A 1 QS(0.999)PS(0.001)FK 106.68 0.032706 11181000.0 104400.0 160530.0 174210.0 135620.0 175230.0 177660.0 171460.0 169500.0 173060.0 142830.0 True False 102911.2368553846 160158.30264793418 159887.1262700469 145593.94721505753 164923.31591543523 170061.8959456877 180337.35983977665 177375.58879017233 153568.1603974092 167517.97519098775 0.6143295174028649 0.9560663711780018 0.9544475814476572 0.8691243256078366 0.9845111590407277 1.01518595692074 1.0765254274006921 1.0588451095349374 0.9167264600848098 1.0 17.353956383902847 -4.400604137803752 1.7492452842328623 0.9898752044737057 9.46150330739777e-16 0.7725441758306584 0.059545023696331564 1.5867637872488463 2.020662377689159 0.017826486918008696 3.639300555139479 3.975537571578479e-05 4.400604137803752 -0.9898752044737047 QS(ph)PSPSTRPIR ddPTM_PC-9_AZD4547_30min_R2 1 QSPSPSTRPIR 11 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 QS(0.94)PS(0.06)PS(0.001)TRPIR 81.278 0.0071881 22113000.0 25954.0 31948.0 39152.0 56315.0 36808.0 40102.0 36564.0 45409.0 28003.0 41221.0 True False 34206.83212326362 42274.566222809015 38632.818898537626 43332.44680807681 31697.844552328115 37594.41560055643 39818.12516614628 38392.082445012835 29483.181410742436 39777.86533669589 0.8599464006859897 1.0627660852330822 0.971213979722991 1.0893607900095572 0.7968714329948271 0.9451089263423801 1.0010121163895955 0.9651619592968795 0.7411956665141506 1.0 15.279678236143532 -6.250766336935429 24.99799628309552 0.9129666620032124 0.9988458353821067 0.16195866877346166 0.09716120344269523 1422.995385240236 3332883.7533569476 0.028282934569586575 0.036139173385429886 5.613499173833798e-07 6.250766336935429 0.08587917337889428 QS(ph)SFEIPDDVPLPAGWEMAK ddPTM_PC-9_AZD4547_30min_R2 1 QSSFEIPDDVPLPAGWEMAK 20 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 QS(0.925)S(0.075)FEIPDDVPLPAGWEMAK 99.42299999999999 0.00024905 4464900.0 12009.0 9138.0 10510.0 16205.0 13106.0 10420.0 9400.0 11489.0 9032.9 11871.0 True False 15827.612197282622 12091.679796670483 10370.630532887995 12469.187614754233 11286.458126027293 9768.435752775378 10236.581789787097 9713.639040955595 9510.360652969164 11455.399903251193 1.3816726025243813 1.05554410136644 0.9053049758607444 1.0884986748664545 0.9852522147938326 0.8527363370355118 0.8936031807044833 0.847952853937359 0.8302076517005748 1.0 13.483740202955623 -1.522878745721129 0.7542770266971769 0.9026631702603652 85.60782570246378 0.7688956097651843 0.07573570842799024 189.21084611250336 0.8026330453302815 0.029951159176248326 27246.89734448243 0.029999999969551206 1.522878745721129 84.70516253220342 QS(ph)SFEIPDDVPLPAGWEMAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSSFEIPDDVPLPAGWEMAK 20 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 QS(0.5)S(0.5)FEIPDDVPLPAGWEMAK 74.905 0.0016830999999999999 6532200.0 9078.3 10557.0 8687.5 9511.0 8444.3 8298.6 8821.1 9310.7 7457.3 4828.8 True False 10615.076885401848 11605.0291912176 8894.642947527216 8978.12950507804 6789.700032914753 7863.406807149622 7985.50154876648 9066.303990502101 7566.34890467446 5704.223215240232 1.8609154103649144 2.034462669730721 1.5593083601221978 1.5739442806324206 1.190293538088482 1.378523685072597 1.3999279564360758 1.589402035719648 1.3264468480930238 1.0 12.477814722478119 -1.522878745280653 0.2864622808372089 1.2376266113384295 7.439971973633698 0.657484751295995 0.16890717717584644 34.2429659604484 0.4849002498013363 0.18984669169023183 107.1309222099453 0.029999999999978214 1.522878745280653 6.202345362295269 QS(ph)SPAMPHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSSPAMPHK 9 0 Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5 Q9UKE5-6 TNIK TRAF2 and NCK-interacting protein kinase 1 QS(0.5)S(0.5)PAMPHK;QS(0.714)S(0.286)PAMPHK 74.53699999999999 0.018919 22757100.0 33011.0 38898.0 42960.0 42169.0 57138.0 45570.0 45512.0 48524.0 40146.0 35700.0 True False 38599.11030303036 42759.53637207372 43984.329326707244 39806.40764374259 45942.21906856498 43180.22897859982 41200.7738816542 47250.29641542782 40733.059301229805 42172.12739895549 0.9152753888338668 1.0139288437493619 1.042971555847966 0.9439032389133991 1.0893977112879267 1.023904451632414 0.9769669310700851 1.1204152915605132 0.9658763219575845 1.0 15.364002180642622 -4.76453333735863 4.703836604570774 1.0233694990343396 0.9074332531694596 0.2697183149742154 0.051462726241348435 0.23725929410338795 12.447814775464161 0.012094402499984336 0.09209542536961189 1.7197553241325485e-05 4.76453333735863 -0.11593624586488005 QS(ph)SPAMPHK ddPTM_PC-9_Lapatinib_30min_R1 6 QSSPAMPHK 9 0 Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5 Q9UKE5-6 TNIK TRAF2 and NCK-interacting protein kinase 1 QS(0.966)S(0.034)PAMPHK;QS(0.5)S(0.5)PAMPHK;QS(0.657)S(0.343)PAMPHK;QS(0.94)S(0.06)PAMPHK;QS(0.5)S(0.5)PAMPHK;QS(0.754)S(0.246)PAMPHK 92.11200000000001 0.0041259999999999995 17950600.0 291680.0 289492.7 282385.0 287466.2 277319.6 249413.0 210685.0 220695.3 265279.3 202488.8 True False 287520.5897124392 288822.39743952866 259168.39533762223 308607.42330713157 261008.20635931098 238746.18740009994 221593.23841037776 230949.60932580347 235400.75171912898 237488.7192806341 1.2106705134599838 1.2161520695146573 1.0912871824929495 1.2994613985957724 1.0990341231782235 1.005294854102017 0.933068480396018 0.9724655976307508 0.9912081400420631 1.0 17.857499461461856 -6.634032922687826 2.9702668205695724 0.9733738918874778 1.1978361263036919 0.8075287961378619 0.05139673879118046 0.10562661303946361 1.874111171632219 0.01759977032212288 0.017560313363526866 2.3225607226486245e-07 6.634032922687826 0.22446223441621405 QS(ph)SPSGSEQLVR ddPTM_PC-9_AZD4547_30min_R2 1 QSSPSGSEQLVR 12 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 QS(0.468)S(0.215)PS(0.102)GS(0.215)EQLVR 101.38 0.0027386999999999997 9336700.0 22985.0 24844.0 29615.0 30038.0 38991.0 37680.0 31951.0 36612.0 23516.0 34101.0 True False 30293.751882300017 32874.337149100604 29222.285749902763 23113.203182473782 33577.772683651005 35323.86364343341 34794.57710271143 30954.456660063202 24759.00775113449 32907.134369536594 0.9205831034118885 0.9990033401247375 0.8880228044698709 0.7023766616357384 1.0203797239402057 1.0734408911683928 1.0573566422399308 0.940660961615635 0.752390271152108 1.0 15.006112778212787 -5.255196409409692 24.555949476264445 0.9320749556076635 0.9597932088234824 0.010201088135844416 0.1175705935601913 3610.1838545619376 14200070.754132586 0.0326317068976298 0.08182286696404527 5.556529067561774e-06 5.255196409409692 0.02771825321581889 QS(ph)SPSGSEQLVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSSPSGSEQLVR 12 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 QS(0.497)S(0.497)PS(0.006)GS(0.001)EQLVR;QS(0.5)S(0.5)PSGSEQLVR 209.22 4.0486e-08 263704000.0 434269.0 582280.0 601130.0 473590.0 576620.0 478239.0 525090.0 407180.0 424614.0 355283.0 True False 507782.16449627955 640084.9102455418 615463.2189982209 447056.2876994962 463635.4503013038 453159.30494835664 475349.6738776107 396491.9564428725 430823.1764592332 419692.9954813201 1.2098895382181336 1.525126502317409 1.4664605452668658 1.0651983533506315 1.1047014253111107 1.0797399761905868 1.1326128360385463 0.9447190225039622 1.0265198159076938 1.0 18.67897485982244 -5.767682454450757 24.99560145255388 1.0550935953811087 1.4129556478705438 0.7580804354433552 0.09049583885629486 65.69946920360172 263044.1205225555 0.0254005423306958 0.03875140672495612 1.7073302910617047e-06 5.767682454450757 0.35786205248943515 QS(ph)SSEQCSDGEGR ddPTM_PC-9_Lapatinib_30min_R1 1 QSSSEQCSDGEGR 13 0 O60343-2;A0A3B3IRT3;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 QS(0.493)S(0.253)S(0.253)EQCSDGEGR 100.11 0.002336 3022000.0 2191.3 2822.5 2291.5 2963.7 1813.9 3315.0 3124.7 3192.9 4656.0 2545.6 True False 2160.0516601647973 2815.9646746638823 2103.1017154457986 3181.6603846133776 1707.2099682646112 3173.2251776424305 3286.4816767254792 3341.253790254516 4131.592250146407 2985.603568201212 0.7234891072515032 0.9431810387205777 0.7044142557455779 1.065667397540755 0.5718140165853243 1.0628421038343876 1.1007763092624994 1.119121716573905 1.3838381941094875 1.0 11.543806900181679 -6.957358654595383 10.475422976109233 1.1496449273104892 0.8184001102046412 0.5381150938591512 0.1549456701794937 0.3776835771405237 90.57065993982332 0.05170265282497569 0.045558309523006435 1.1031672120339557e-07 6.957358654595383 -0.33124481710584797 QS(ph)STDSSGGHPGPR ddPTM_PC-9_AZD4547_30min_R2 3 QSSTDSSGGHPGPR 14 0 Q9GZV5;C9JR84;C9J038;C9JQS8 Q9GZV5 WWTR1 WW domain-containing transcription regulator protein 1 1 QS(0.728)S(0.233)T(0.039)DSSGGHPGPR;QS(0.466)S(0.466)T(0.069)DSSGGHPGPR;QS(0.734)S(0.23)T(0.035)DSSGGHPGPR 142.4 4.4582e-05 6707500.0 9321.099999999999 7079.5 14770.0 23393.100000000002 20889.1 14078.5 12176.2 15223.7 12849.8 16862.3 True False 12285.015909075773 9367.809927831986 14574.140149453435 18000.182214792185 17989.00903711251 13198.169169428798 13259.858211575067 12871.226970823885 13529.014194613372 16271.956009484658 0.7549808948546222 0.5757027564708043 0.8956600018435649 1.1062088789018463 1.1055222264998141 0.8110991181229719 0.8148902445315186 0.7910067457975831 0.8314313403211961 1.0 13.990100063600364 -5.322181588361923 7.453493242461841 0.9183653954162674 0.6659540876174463 0.4258768968548208 0.11808592258103824 0.26259098892950655 28.680914152986684 0.0347614013272054 0.07319088924212458 4.76231821856771e-06 5.322181588361923 -0.25241130779882104 QS(ph)STDSSGGHPGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSSTDSSGGHPGPR 14 0 Q9GZV5;C9JR84;C9J038;C9JQS8 Q9GZV5 WWTR1 WW domain-containing transcription regulator protein 1 1 QS(0.479)S(0.26)T(0.26)DS(0.001)SGGHPGPR;QS(0.485)S(0.485)T(0.03)DS(0.001)SGGHPGPR 108.96 0.00035996 6128100.0 27647.1 29160.1 35239.4 40297.4 43362.2 37665.4 34281.5 34751.5 40199.2 37536.8 True False 32327.207974884463 32054.922015612803 36079.64094216874 38039.667323933514 34865.68818815723 35690.16011785284 31034.108143433128 33839.30994725786 40787.037250585294 44341.924698854724 0.7290438607352427 0.7229032621680657 0.8136688063768377 0.857871361747994 0.7862917188404714 0.8048852267969924 0.699881846676689 0.7631448155910082 0.9198301049759969 1.0 15.436383772515796 -8.419080610795417 3.278819670991636 0.9972997926701225 0.7739399462572573 0.7442976442517673 0.04509165365361314 0.12404562898864706 2.476123163992904 0.0476626971661669 0.012713592379001746 3.809950991047224e-09 8.419080610795417 -0.22335984641286522 QS(ph)STDSSGGHPGPR ddPTM_PC-9_Lapatinib_30min_R1 2 QSSTDSSGGHPGPR 14 0 Q9GZV5;C9JR84;C9J038;C9JQS8 Q9GZV5 WWTR1 WW domain-containing transcription regulator protein 1 1 QS(0.599)S(0.2)T(0.2)DS(0.001)SGGHPGPR;QS(0.708)S(0.243)T(0.05)DSSGGHPGPR 90.87200000000001 0.0026982 3471470.0 10724.6 9710.8 11543.7 9356.6 10872.2 12125.6 9117.1 10466.1 13609.5 9771.0 True False 10571.665237349232 9688.315239229772 10594.621545970624 10044.715576702609 10232.718571567619 11607.016354154166 9589.138827687097 10952.393214376525 12076.654795611592 11459.904330960897 0.9224915786415482 0.8454097834879064 0.9244947636558742 0.8765095489990337 0.8929148338457045 1.012837107443892 0.8367555741089735 0.9557141925510457 1.053818116350626 1.0 13.484307379855053 -8.023987403879744 5.864122990450718 1.0215832805756788 0.9026918265241918 0.5206887762878094 0.047907310324633946 0.13981051472574413 15.86775660677859 0.03022698226174296 0.01205217344365744 9.46264606084572e-09 8.023987403879744 -0.11889145405148704 QS(ph)STPSAPELGQQPDVNISEWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSSTPSAPELGQQPDVNISEWK 22 0 Q93100-4;Q93100-2;I3L213;Q93100-3;Q93100 Q93100-4;Q93100-3 PHKB Phosphorylase b kinase regulatory subunit beta 1 QS(0.763)S(0.188)T(0.046)PS(0.003)APELGQQPDVNISEWK;QS(0.65)S(0.243)T(0.093)PS(0.014)APELGQQPDVNISEWK 172.32 8.1617e-10 3954100.0 44986.0 51665.0 53718.0 53569.0 62715.0 56442.0 52764.0 45960.0 49166.0 44077.6 True False 52601.24128599934 56793.959757910154 54998.84084664946 50567.702603041274 50426.44595339447 53482.08215953764 47765.81194172092 44753.59869864524 49884.95973706635 52068.51996191036 1.0102311593354043 1.0907542561120729 1.0562781674394186 0.9711761087127697 0.968463209445609 1.0271481155727364 0.9173645030944417 0.8595135550498421 0.958063716302262 1.0 15.668123778519615 -6.2679732576140825 0.8427465535494344 0.9309640248204374 1.0601674462174493 0.436743729487557 0.0477063616411383 0.5680249216013397 0.8678386384989896 0.026117122700759055 0.04334591063628559 5.395438447781123e-07 6.2679732576140825 0.1292034213970119 QS(ph)STPSAPELGQQPDVNISEWK ddPTM_PC-9_Lapatinib_30min_R1 2 QSSTPSAPELGQQPDVNISEWK 22 0 Q93100-4;Q93100-2;I3L213;Q93100-3;Q93100 Q93100-4;Q93100-3 PHKB Phosphorylase b kinase regulatory subunit beta 1 QS(0.692)S(0.217)T(0.069)PS(0.022)APELGQQPDVNISEWK;QS(0.481)S(0.172)T(0.062)PS(0.284)APELGQQPDVNISEWK 147.17 7.9104e-06 6161700.0 53148.0 45023.0 55138.0 37225.0 45966.0 46956.0 42643.0 37594.0 57722.0 27942.0 True False 52390.09977385048 44918.75200970488 50604.76647883502 39962.650678959704 43262.370252633045 44947.801339782214 44850.84588619854 39340.75448364441 51220.74052039329 32771.73746962536 1.5986366246955472 1.3706551888296443 1.544158790047012 1.2194242284529246 1.32011219401263 1.3715416029266772 1.3685830947403614 1.200447627169831 1.5629546821515787 1.0 15.000164542279478 -13.781840693180671 0.16124583816144966 5.913379851306021e-28 1.4836980750950302 0.44155735684670927 0.13127516455597266 98.24915356017956 1.1240046533530723 33.02345270883527 0.5456289600351785 1.65256787789168e-14 13.781840693180671 1.4836980750950302 QS(ph)VSGLHR ddPTM_PC-9_AZD4547_30min_R2 1 QSVSGLHR 8 0 Q8N1G4;J3KRP5 Q8N1G4 LRRC47 Leucine-rich repeat-containing protein 47 1 QS(0.994)VS(0.006)GLHR 84.31 0.0079748 2696600.0 3024.9 3486.8 8948.9 14688.0 11805.0 11810.0 9625.7 15252.0 8382.0 13482.0 True False 3986.7552781713894 4613.83991190968 8830.231738892611 11301.908527337862 10166.07951913262 11071.518833040029 10482.368652548257 12895.153856093191 8825.055407807851 13009.99928360143 0.3064377784552633 0.3546379835489489 0.6787265353675119 0.8687093889069967 0.7814050790876327 0.8510007258029002 0.805716312818007 0.9911725262235028 0.6783286620877429 1.0 13.66733326216283 -5.361293309740493 2.245034452124543 0.8493720478586636 0.29833364343501373 0.8423567084539787 0.08957196253492553 0.10880059485091345 1.0369257012081752 0.023437097713932712 0.07112550961332406 4.352178410560918e-06 5.361293309740493 -0.5510384044236498 down QS(ph)VSGLHR ddPTM_PC-9_Lapatinib_30min_R1 2 QSVSGLHR 8 0 Q8N1G4;J3KRP5 Q8N1G4 LRRC47 Leucine-rich repeat-containing protein 47 1 QS(0.969)VS(0.031)GLHR;QS(0.998)VS(0.002)GLHR 78.513 0.01248 3421300.0 6471.3 12930.900000000001 19229.2 16417.1 18020.9 17457.7 14583.5 12568.8 20297.7 12258.7 True False 6379.018075308925 12900.959295522125 17648.249402858553 17624.46829984015 16960.94609245257 16711.074866886363 15338.562272386464 13152.792332660272 18011.559281743288 14377.599961309004 0.44367753258368925 0.8972957468728711 1.2274822954005582 1.2258282569600396 1.1796785373146774 1.1622993345104107 1.066837463391906 0.9148113988464859 1.2527514557515502 1.0 13.811535247753696 -4.842929501459025 2.7542365945334244 1.128864129028798 0.3630684877931079 0.8024194034053603 0.10360611926620736 0.16269914796178866 1.861318529611382 0.027814464142745632 0.2695555006985446 1.4357224736733754e-05 4.842929501459025 -0.7657956412356901 down QS(ph)WT(ph)VGKLELLSSGPSMPFIK ddPTM_PC-9_AZD4547_30min_R2 4 QSWTVGKLELLSSGPSMPFIK 21 1 Q9UHV7 Q9UHV7 MED13 Mediator of RNA polymerase II transcription subunit 13 2 QS(0.999)WT(0.999)VGKLELLSSGPSMPFIK;QS(1)WT(1)VGKLELLSSGPSMPFIK;QS(1)WT(1)VGKLELLSSGPSMPFIK;QS(1)WT(1)VGKLELLSSGPSMPFIK 55.67 0.013623 17833000.0 34211.9 37597.5 47220.1 65918.5 52113.7 56570.3 41399.4 53362.3 46032.3 48476.8 True False 45090.57254827324 49750.15661581514 46593.93062093474 50722.0082556728 44878.61230294124 53032.950198198545 45083.86639873527 45116.3826786652 48465.47340119698 46779.641987189534 0.963893066146619 1.063500157385537 0.996030081497724 1.0842752552395094 0.9593620300734904 1.1336758458459657 0.9637497099931067 0.9644448046656746 1.0360377151768092 1.0 15.513593200083683 QS(ph)WT(ph)VGKLELLSSGPSMPFIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSWTVGKLELLSSGPSMPFIK 21 1 Q9UHV7 Q9UHV7 MED13 Mediator of RNA polymerase II transcription subunit 13 2 QS(1)WT(1)VGKLELLSSGPSMPFIK 52.185 0.025356 4036800.0 25054.0 25931.0 22620.0 30511.0 32467.0 31216.0 29577.0 22718.0 29316.0 24091.0 True False 29295.147360944 28505.258307991233 23159.346586827716 28801.567587996626 26105.324416309613 29578.978007372665 26775.252441063603 22121.67657171069 29744.691039576875 28458.50759574894 1.029398581860984 1.0016427675304125 0.8137934327338796 1.0120547428951943 0.9173117855347117 1.0393720720545128 0.9408523040422269 0.7773308736335552 1.045195041922018 1.0 14.796572386436107 -7.521305613441166 24.999954313837197 0.9185761181579317 0.9652394726734318 0.003985040813124785 0.0899857148013901 212.54793900786206 3377957.662872785 0.040469489601666506 0.023771914568852838 3.010886514810801e-08 7.521305613441166 0.04666335451550008 QS(ph)WT(ph)VGKLELLSSGPSMPFIK ddPTM_PC-9_Lapatinib_30min_R1 3 QSWTVGKLELLSSGPSMPFIK 21 1 Q9UHV7 Q9UHV7 MED13 Mediator of RNA polymerase II transcription subunit 13 2 QS(0.998)WT(0.998)VGKLELLS(0.001)S(0.001)GPS(0.001)MPFIK;QS(1)WT(1)VGKLELLSSGPSMPFIK;QS(1)WT(1)VGKLELLSSGPSMPFIK 73.76 0.0013599 5651000.0 22875.7 23314.5 21455.8 17746.0 22354.7 23878.2 21768.1 21429.1 21285.7 17665.9 True False 22549.488323110403 23260.516707688606 19691.786945783097 19051.10003892061 21039.8404970312 22856.985048802868 22895.14570586869 22424.774216775688 18888.280317642053 20719.427276667902 1.088325850999913 1.12264284128559 0.9504020879939076 0.9194800505115316 1.015464385964187 1.103166836785207 1.1050086182474195 1.0823066640470402 0.911621738642945 1.0 14.338696504362977 -7.500211293961385 0.0052228784493517375 3.586066694906843e-08 2.057537682254313 0.04163749635400216 0.07543405457066359 27425.838423402354 108.90814815208121 21333.706251146967 21561.469963083026 3.160739515687721e-08 7.500211293961385 2.057537646393646 QSAGPNS(ph)PTGGGGGGGSGGTR ddPTM_PC-9_AZD4547_30min_R2 3 QSAGPNSPTGGGGGGGSGGTR 21 0 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 QSAGPNS(0.664)PT(0.336)GGGGGGGSGGTR;QS(0.003)AGPNS(0.711)PT(0.286)GGGGGGGSGGTR;QSAGPNS(0.677)PT(0.323)GGGGGGGSGGTR 276.96 5.5040999999999987e-101 15531400.0 13199.599999999999 15152.9 18189.8 23406.8 21114.0 17271.1 14598.2 24842.1 15213.9 16832.4 True False 17396.798231264176 20050.778593890158 17948.591366995817 18010.72389145507 18182.6855541691 16191.135386733093 15897.411519539344 21003.324259667777 16018.075694207566 16243.10279938382 1.0710267887933407 1.2344180075404547 1.1049977081765865 1.1088228717076336 1.119409621347644 0.9968006474321706 0.9787176573272941 1.2930610930114004 0.9861462980345854 1.0 13.987539625724668 -6.037947201181428 1.5744407539008582 1.0679439278838805 1.1489070355141355 0.116946798975746 0.09576074916726758 0.9267953586597284 4.62436981972319 0.03309292484665563 0.05468648886868533 9.163318852747187e-07 6.037947201181428 0.08096310763025505 QSAGPNS(ph)PTGGGGGGGSGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSAGPNSPTGGGGGGGSGGTR 21 0 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 QS(0.067)AGPNS(0.643)PT(0.29)GGGGGGGSGGTR;QSAGPNS(0.677)PT(0.323)GGGGGGGSGGTR 220.55 1.9674e-32 7950900.0 7847.900000000001 7756.799999999999 7157.200000000001 10358.8 11423.0 9284.4 9858.6 8134.799999999999 7703.8 7288.700000000001 True False 9176.394466909578 8526.84384109469 7327.854791832157 9778.430019682719 9184.745150691619 8797.50971974791 8924.722037916956 7921.27011953306 7816.4535008422845 8610.083612682542 1.065772979648289 0.9903322923060537 0.85107823819949 1.1356951290553343 1.0667428522021096 1.0217682098684027 1.0365430162340068 0.9199992097481065 0.9078255046592986 1.0 13.071811532390681 -7.761120881527298 24.999983344212772 0.935434253209872 1.0219005769713685 0.20740067888317681 0.0724191196356823 13.469255712750906 1057549.3924642222 0.038000158081350204 0.02019711610920502 1.733321477899995e-08 7.761120881527298 0.08646632376149654 QSAGPNS(ph)PTGGGGGGGSGGTR ddPTM_PC-9_Lapatinib_30min_R1 1 QSAGPNSPTGGGGGGGSGGTR 21 0 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 QS(0.005)AGPNS(0.687)PT(0.307)GGGGGGGSGGTR 262.33 1.2842999999999998e-74 6197900.0 7427.9 5978.5 6562.7 6369.7 7462.4 8173.3 7481.4 5355.1 9695.5 5684.7 True False 7321.976783889972 5964.657150567947 6023.14013875459 6838.148986696299 7023.476303642883 7823.74701189288 7868.75028522866 5603.91749575369 8603.490691858782 6667.292820613385 1.0981933718663877 0.8946145476207243 0.9033861719906382 1.0256260180375874 1.0534225048475867 1.1734518375590264 1.1802016945919502 0.8405086811888569 1.2904024051949872 1.0 12.702885374844355 -6.134236783476999 2.7410849333639367 1.091711547391405 0.9594999108525187 0.16661321534587914 0.12409396028694142 0.47645858722483353 6.939329106912151 0.037906332527998764 0.05188217352253103 7.341135099866921e-07 6.134236783476999 -0.13221163653888623 QSAGPNSPT(ph)GGGGGGGSGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSAGPNSPTGGGGGGGSGGTR 21 0 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 QSAGPNS(0.469)PT(0.531)GGGGGGGSGGTR;QS(0.001)AGPNS(0.245)PT(0.754)GGGGGGGSGGTR 200.14 6.4214e-19 8093100.0 5408.6 4878.6 6957.5 5607.9 8348.7 8231.4 8385.6 7126.6 6951.8 7340.700000000001 True False 6324.169155280664 5362.915166455827 7123.393186465688 5293.707544057104 6712.832166644408 7799.730893448461 7591.255261513443 6939.534301256863 7053.456923486505 8671.510801050774 0.7293041893592902 0.6184522270105428 0.8214708313114836 0.6104711930262068 0.774124869432323 0.8994662028793559 0.8754247599615017 0.8002681955278153 0.8134057703799203 1.0 13.082067654729636 -6.5466049094633325 5.155162629670862 0.8636691258144762 0.6973322040547916 0.5639522928648499 0.0754173942749027 0.14242046936448596 10.417212642655757 0.02390537118164896 0.024569892425528546 2.840501942026005e-07 6.5466049094633325 -0.16633692175968462 QSAGPNSPT(ph)GGGGGGGSGGTR ddPTM_PC-9_Lapatinib_30min_R1 1 QSAGPNSPTGGGGGGGSGGTR 21 0 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 QSAGPNS(0.224)PT(0.776)GGGGGGGSGGTR 175.23 2.2195e-41 0.0 3279.2 2492.3 2449.7 2614.9 3171.1 3340.2 3034.1 2550.3 3288.0 2712.6 True False 3232.438006668368 2486.5292324764564 2248.295122115458 2807.208469050685 2984.5821326224755 3197.347432386503 3191.190852034683 2668.796248327881 2917.6708158250426 3181.4692956876997 1.0160204943828166 0.7815663146102981 0.7066845262856675 0.8823622698027279 0.9381143915699285 1.0049908187768228 1.003055681335715 0.838856515744245 0.9170828144655613 1.0 11.635477482890767 -6.0877187043461625 4.160842343225753 0.9468438904323754 0.8249491989918499 0.26217322859812675 0.08654228943893301 0.3095365229570245 9.649774074751548 0.026967779480940122 0.036204902638608136 8.171114489481505e-07 6.0877187043461625 -0.12189469144052545 QSCELS(ph)PSKLEK ddPTM_PC-9_AZD4547_30min_R2 1 QSCELSPSKLEK 12 1 E9PGC0;P20936-2;P20936-4;P20936 E9PGC0 RASA1 Ras GTPase-activating protein 1 1 QS(0.001)CELS(0.939)PS(0.06)KLEK 119.62 0.0028414 0.0 14332.0 14086.0 10850.0 19550.0 16635.0 15348.0 12715.0 12448.0 12482.0 15473.0 True False 18889.277875880958 18639.02403325678 10706.12191073594 15043.049544489057 14325.517391001373 14388.287133742462 13846.610367781155 10524.44762658328 13141.773037491957 14931.29497961465 1.2650796800726294 1.2483193225171834 0.717025678305382 1.0074845862349504 0.9594289986608442 0.9636329034679482 0.927354953919644 0.7048583288289505 0.880149582165118 1.0 13.866051674268345 -5.241180314142415 24.278388180334062 0.8943773250087507 1.2566996817532308 0.6728498960875047 0.10088554481048935 326.8362763717372 391677.05765934865 0.026198446056689344 0.06910382463644131 5.738781450414928e-06 5.241180314142415 0.3623223567444801 QSCELS(ph)PSKLEK ddPTM_PC-9_Lapatinib_30min_R1 1 QSCELSPSKLEK 12 1 E9PGC0;P20936-2;P20936-4;P20936 E9PGC0 RASA1 Ras GTPase-activating protein 1 1 QS(0.015)CELS(0.975)PS(0.01)KLEK 55.097 0.038748000000000005 21406000.0 76264.0 75665.0 64691.0 62142.0 70578.0 69454.0 66173.0 66850.0 71223.0 51139.0 True False 75176.46137489512 75489.80234134362 59372.35569448147 66712.12997963498 66426.74080168686 66483.61432518181 69599.11415302426 69956.09504792347 63201.11572856055 59978.30801156578 1.2533941664442858 1.258618404620329 0.9898971421973514 1.112270955805734 1.1075127492572416 1.1084609841338238 1.1604047606611922 1.166356594027855 1.0537328881697248 1.0 15.872153203894255 -5.232727849400539 24.54034869360553 1.0982469396454706 1.2560063843159122 0.5799830718628332 0.0568125564964061 416.06596181759625 355618.55494979 0.014362297134450506 0.03798021129518993 5.851566576446789e-06 5.232727849400539 0.15775944467044156 QSDEVGDRDHR ddPTM_PC-9_AZD4547_30min_R2 2 QSDEVGDRDHR 11 1 P40222 P40222 TXLNA Alpha-taxilin 0 ; 68.132 0.01711 26816000.0 59991.0 57522.0 89667.0 91439.0 88755.0 84995.0 71723.0 107131.0 80713.0 78715.0 False True 79066.89010968288 76114.86159598165 88477.95699262296 70359.15126846729 76432.90027281779 79680.24921373719 78106.20805413823 90576.3655754736 84979.32440114477 75959.21180898143 1.0409124611313303 1.002049123250405 1.164808782049017 0.9262754258878185 1.006236089771805 1.0489873093221826 1.028265120108881 1.1924342475176108 1.1187494232410768 1.0 16.21293731498455 -7.717453747935204 24.96699657737206 1.116693966373931 1.0308060550479683 0.174316769034222 0.07078946636275615 181.8562792878412 103224.51251730027 0.03244131465935104 0.01872987368862953 1.9166651753943722e-08 7.717453747935204 -0.08588791132596274 QSDEVGDRDHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSDEVGDRDHR 11 1 P40222 P40222 TXLNA Alpha-taxilin 0 ; 64.439 0.021261000000000002 20385000.0 40121.0 39870.0 50851.0 48661.0 58447.0 51149.0 52970.0 47247.0 49195.0 43793.0 False True 46912.692874129294 43828.03010834951 52063.480693491416 45934.68193109059 46994.729915300064 48466.656397331644 47952.298130410076 46006.81631233446 49914.38380720374 51732.32423480272 0.9068352054162871 0.8472078290823123 1.0064013450697797 0.8879299859523461 0.9084210038969125 0.936873746042245 0.9269310598295205 0.8893243633036605 0.9648587134931786 1.0 15.658778390087774 -14.522878744963702 0.1700071184602337 1.3243056728809168 0.8989537509985498 0.29596509101616886 0.04043799847929291 173.22840923223816 1.628647841339016 18.85599325752275 0.14281091336708726 3.0000000021872425e-15 14.522878744963702 -0.42535192188236703 QSDEVGDRDHR ddPTM_PC-9_Lapatinib_30min_R1 2 QSDEVGDRDHR 11 1 P40222 P40222 TXLNA Alpha-taxilin 0 ; 68.132 0.01711 24149000.0 50854.0 56722.0 66882.0 55996.0 61387.0 63361.0 55151.0 54274.0 68354.0 52531.0 False True 50128.81263451859 56590.66369398926 61383.220131985945 60114.132637180075 57776.337351485556 60651.197731705004 58006.44892408453 56795.7681769782 60655.25272046989 61610.91335684231 0.8136352782855059 0.9185168764862092 0.9963043361565248 0.9757059157524077 0.9377614160149291 0.9844229605950043 0.9414963317962647 0.9218459049296116 0.9844887766743959 1.0 15.910898302730363 -4.828224698956841 3.0454679925945247 0.9637357140508352 0.7978031398305652 0.7718354823090026 0.025372051230841897 0.15268394749204892 2.2122623140517717 0.006481760317832171 0.05868213046838275 1.485167035172227e-05 4.828224698956841 -0.16593257422027008 QSEKPHS(ph)TPPQSCTSDLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSEKPHSTPPQSCTSDLSK 19 1 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 QS(0.009)EKPHS(0.496)T(0.496)PPQSCTSDLSK 72.676 0.0022892 5834500.0 14930.0 19177.0 29913.0 42889.0 42558.0 41706.0 40063.0 29745.0 38625.0 28059.0 True False 17457.354119058597 21080.765823622216 30626.239365684236 40486.0683780141 34219.06540515925 39518.86394078304 36267.94260899793 28964.225267432623 39189.8175536791 33145.87458507819 0.5266825611811629 0.6359996858587186 0.9239834443672136 1.2214512027460684 1.032377809712832 1.1922709669146543 1.0941917527596405 0.8738410324062443 1.1823437469748288 1.0 15.01654169978124 -5.312220732652175 2.6214591833808836 1.0827450153121645 0.5485194907252252 0.8001966439474372 0.09968648248852466 0.11618965893352044 1.5369528736465856 0.027008947886376866 0.07957423290586166 4.872807639217974e-06 5.312220732652175 -0.5342255245869393 QSEKPHST(ph)PPQSCTSDLSK ddPTM_PC-9_Lapatinib_30min_R1 1 QSEKPHSTPPQSCTSDLSK 19 1 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 QS(0.007)EKPHS(0.182)T(0.784)PPQS(0.026)CT(0.001)SDLSK 57.578 0.016299 8022900.0 35383.0 23670.0 64481.0 33166.0 50397.0 62078.0 39151.0 42800.0 76271.0 39242.0 True False 34878.4319315525 23615.193569280476 59179.62108385801 35605.13827853268 47432.74754431425 59423.068650885914 41178.047212685735 44788.644249081815 67680.55681076384 46024.927413321806 0.7578161203456243 0.5130957265224304 1.2858167173714783 0.773605528125762 1.0305882096966643 1.2911061894186942 0.8946901065783506 0.9731388351112934 1.4705195774230349 1.0 15.490127825828091 -5.2544184007229315 24.970911141315327 1.0757687285455169 0.6354558991617487 0.43993950223416933 0.2046142404320119 489.53594432417486 1741079.1695727909 0.0509217273129455 0.12873183875178862 5.566492128525978e-06 5.2544184007229315 -0.44031282938376815 QSEKPHSTPPQS(ph)CTSDLSK ddPTM_PC-9_AZD4547_30min_R2 1 QSEKPHSTPPQSCTSDLSK 19 1 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 QS(0.04)EKPHS(0.167)T(0.132)PPQS(0.621)CT(0.03)S(0.007)DLS(0.002)K 44.382 0.042099 7402600.0 48085.0 36315.0 102970.0 169830.0 146290.0 124660.0 80952.0 139040.0 96359.0 140580.0 True False 63375.029769867164 48053.113571469534 101604.5505205972 130678.3173473441 125980.1586492089 116864.99049337585 88156.57117519608 117554.562821348 101452.34001920257 135658.33698922175 0.4671664947131292 0.3542216028734557 0.7489738763985425 0.9632899845862528 0.9286576958349283 0.8614655987022821 0.649842635047194 0.8665487535107251 0.7478518627812982 1.0 17.04961818673342 -5.364719425124824 4.222190377345017 0.848557249273895 0.4113100705745826 0.7541288607859783 0.10062502288064931 0.10512419306344124 3.1794152973212544 0.027493404220326676 0.061540196894101604 4.317979487319131e-06 5.364719425124824 -0.4372471786993124 QSELSAEES(ph)PEKLGTSQLHR ddPTM_PC-9_AZD4547_30min_R2 2 QSELSAEESPEKLGTSQLHR 20 1 F8W9X7;Q567U6 F8W9X7 CCDC93 Coiled-coil domain-containing protein 93 1 QSELS(0.023)AEES(0.976)PEKLGTSQLHR;QS(0.005)ELS(0.083)AEES(0.911)PEKLGT(0.001)S(0.001)QLHR 59.428999999999995 0.007274500000000001 13226700.0 14839.400000000001 13186.3 22071.2 31734.0 32754.0 22880.0 19662.3 24381.0 17201.6 27982.0 True False 19558.020521305323 17448.513602849205 21778.52146693412 24418.216585412574 28206.67247519439 21449.30998306149 21412.206609077744 20613.47666964385 18110.84145823759 27002.35869705793 0.7243078554999082 0.6461847943953994 0.806541447407223 0.9042993932257142 1.0446003177591918 0.7943494945646552 0.7929754155665939 0.7633954093014034 0.6707133129155446 1.0 14.72079781393373 -5.397391290617487 4.724990178442369 0.8466668956036215 0.6869257227607317 0.277147921505259 0.10622601299292754 0.3107953288740919 10.471346178404998 0.030027267317514626 0.06497635870561529 4.005057074108661e-06 5.397391290617487 -0.1597411728428898 QSEPFFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSEPFFK 7 0 P11413;P11413-2;P11413-3;E7EUI8;E7EM57;E9PD92 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 92.47 0.02502 0.0 28176.0 26118.0 25207.0 23313.0 32932.0 28028.0 23663.0 22820.0 20266.0 25307.0 False True 32945.64029863329 28710.822432151286 25808.030478079854 22006.848191765777 26479.211004340035 26558.162339525923 21421.46933471575 22220.999179788625 20562.351910494763 29894.95876989822 1.102046687945489 0.9603900996532143 0.863290385403255 0.736139104962569 0.8857416799986503 0.8883826381546249 0.7165579153193353 0.7433025531436208 0.6878200458064979 1.0 14.86761460073343 -4.92642714000226 1.4026661320084928 0.7987468713627669 1.1787886320271328 0.5049820875571981 0.09143729872803982 0.7563986767055393 1.6514522961803055 0.026959987395151628 0.37863849350732276 1.184603086857217e-05 4.92642714000226 0.3800417606643659 QSFDDNDS(ph)EELEDKDSK ddPTM_PC-9_AZD4547_30min_R2 4 QSFDDNDSEELEDKDSK 17 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 QSFDDNDS(1)EELEDKDSK;QSFDDNDS(1)EELEDKDSK;QSFDDNDS(1)EELEDKDSK;QS(0.001)FDDNDS(0.999)EELEDKDS(0.001)K 108.37 0.00024934 100812700.0 211100.0 194510.0 165016.0 194418.0 192754.0 218201.0 219284.0 188950.0 189861.0 203938.0 True False 278225.4088472278 257381.55364963642 162827.78002046084 149597.9338281573 165993.43427622918 204556.85697613633 238799.85119060337 159752.11913905118 199896.6648510865 196798.19269389627 1.4137599793916045 1.3078451083642455 0.8273845292559486 0.7601590836804321 0.8434703185227853 1.0394244691784749 1.2134250214484301 0.8117560275948912 1.0157444136797011 1.0 17.58635744611231 -5.162115686512083 4.949402547207674 0.9364078590696305 1.3846641397401154 0.6318402957314353 0.1294477309896395 0.1464222166945619 5.6181327226163 0.03608841828108879 0.10246550119316242 6.884688789268567e-06 5.162115686512083 0.44825628067048484 QSFDDNDS(ph)EELEDKDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QSFDDNDSEELEDKDSK 17 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 QSFDDNDS(1)EELEDKDSK;QSFDDNDS(1)EELEDKDSK;QS(0.001)FDDNDS(0.961)EELEDKDS(0.038)K 144.18 5.2842e-05 26259300.0 72688.0 76629.0 52882.0 83823.0 78164.0 67677.0 82801.0 72445.0 65387.0 61795.0 True False 84992.64274655939 84236.22069658185 54142.90743610181 79126.6690678327 62848.32530496891 64127.898981450555 74957.48985267286 70543.3955118224 66343.16117494927 72997.9443310491 1.1643155643001912 1.153953326611043 0.7417045497961036 1.0839574976110222 0.8609602075908988 0.8784891077292194 1.0268438452559312 0.9663750967000493 0.9088360197388562 1.0 16.155568216896093 -5.1396436552440035 10.677657590304253 0.9364072373399359 1.1614986473820679 0.4965733773729061 0.0908973744018622 0.3309080810392039 27.485457394341243 0.0217671807949272 0.05773913711531698 7.250306139391153e-06 5.1396436552440035 0.22509141004213196 QSFDDNDS(ph)EELEDKDSK ddPTM_PC-9_Lapatinib_30min_R1 9 QSFDDNDSEELEDKDSK 17 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 QSFDDNDS(1)EELEDKDSK;QSFDDNDS(1)EELEDKDSK;QS(0.001)FDDNDS(0.903)EELEDKDS(0.096)K;QS(0.01)FDDNDS(0.99)EELEDKDSK;QSFDDNDS(1)EELEDKDSK;QSFDDNDS(1)EELEDKDSK;QS(0.002)FDDNDS(0.98)EELEDKDS(0.018)K;QSFDDNDS(1)EELEDKDSK;QS(0.043)FDDNDS(0.85)EELEDKDS(0.106)K 132.83 1.0955e-05 390105000.0 435707.7 404069.8 319070.49999999994 377632.3 376713.69999999995 333069.8 331769.5 345795.4 332997.5 266277.5 True False 429494.4282989937 403134.2012040743 292837.75513774744 405404.639086423 354556.1408136304 318825.18107762554 348946.9013493694 361862.31667217077 295491.81493086956 312303.2110825339 1.3752481980900577 1.2908423189332372 0.9376712910593731 1.2981122982410986 1.1352945734519846 1.0208834548081802 1.1173336967616112 1.158689068286716 0.9461696340124358 1.0 18.252587877573816 -1.5228787452911374 0.604202782885434 1.073686840407199 21.532968686603283 0.4460153645656013 0.10909578759648156 167.68831876393506 1.2802345317431763 0.04836427351258595 4534.881769076471 0.02999999999925397 1.5228787452911374 20.459281846196085 QSFT(ph)QSLK ddPTM_PC-9_Lapatinib_30min_R1 1 QSFTQSLK 8 0 A0A1B0GUA8;Q9H1H9-3;Q9H1H9-4;Q9H1H9-2;Q9H1H9;H0Y9Z7;H0Y307 A0A1B0GUA8 KIF13A Kinesin-like protein KIF13A 1 QS(0.028)FT(0.486)QS(0.486)LK 81.017 0.045183999999999995 3753500.0 23229.0 22976.0 21698.0 26023.0 26456.0 21499.0 21554.0 21991.0 21720.0 22069.0 True False 22897.750200323106 22922.800483641233 19914.07419670215 27936.81823018319 24899.91009449725 20579.537886616785 22669.960655468036 23012.78214209249 19273.664878260308 25883.59724490595 0.8846432736403949 0.8856110789682674 0.7693704243764402 1.0793251790255438 0.9619957326216587 0.7950802854756582 0.8758427370418778 0.8890874759157189 0.7446285265489317 1.0 14.659750513369112 -6.753699615431991 24.992833294560725 0.8549279535219827 0.9153968652368887 0.07599588107383137 0.09518327889697141 482.6092326863035 1558415.287612369 0.03207922385080924 0.0315133380853145 1.7631951581334504e-07 6.753699615431991 0.06046891171490598 QSFTMVADT(ph)PENLR ddPTM_PC-9_AZD4547_30min_R2 5 QSFTMVADTPENLR 14 0 Q14847;Q14847-2;C9J9W2;F6S2S5 Q14847 LASP1 LIM and SH3 domain protein 1 1 QSFT(0.048)MVADT(0.951)PENLR;QSFT(0.005)MVADT(0.995)PENLR;QSFT(0.001)MVADT(0.999)PENLR;QSFT(0.001)MVADT(0.999)PENLR;QSFTMVADT(1)PENLR 179.9 0.00013025 83953000.0 80410.0 92699.0 130473.0 151212.0 144990.0 133752.0 108725.0 174691.0 119792.0 119448.0 True False 105978.7073680984 122662.1389222541 128742.8427704562 116352.40960211151 124860.6412095754 125388.4662960853 118401.31437176622 147696.51994982787 126123.96055978505 115266.16187714176 0.9194260105672424 1.064164338646024 1.1169179286777917 1.0094238214171436 1.0832376056961113 1.0878167907571397 1.027199244284425 1.2813519383707122 1.0941976249214946 1.0 16.814609524659943 -4.76845578632578 3.481029804496973 1.0925481111713113 0.8954248349125107 0.30739689040145246 0.07491466529709218 0.3791910941110269 7.410659886263356 0.01914487901826966 0.20285582760481966 1.704292817287495e-05 4.76845578632578 -0.19712327625880066 QSFTMVADT(ph)PENLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSFTMVADTPENLR 14 0 Q14847;Q14847-2;C9J9W2;F6S2S5 Q14847 LASP1 LIM and SH3 domain protein 1 1 QSFT(0.012)MVADT(0.988)PENLR 81.128 0.041198 8267000.0 12385.0 16157.0 20596.0 15279.0 12502.0 13858.0 16595.0 11515.0 10565.0 7689.1 True False 14481.535885099851 17760.960182106905 21087.086750764975 14422.967165186348 10052.322846357923 13131.262084385253 15023.001462604407 11212.743451151011 10719.49313798368 9083.072963117887 1.5943432298631308 1.9553911164454871 2.3215806849058436 1.587895112562816 1.106709467949416 1.4456849722230758 1.6539558279016136 1.2344658571697837 1.1801615137861965 1.0 13.148964753833186 -5.985227645777833 8.550240746068926 1.3129498622725781 1.9578152209853645 0.6255081421907966 0.23720704010968857 0.12095759514636253 54.2039340612027 0.06878915976755821 0.10028804976532496 1.0345997144846966e-06 5.985227645777833 0.6448653587127864 QSFTMVADT(ph)PENLR ddPTM_PC-9_Lapatinib_30min_R1 5 QSFTMVADTPENLR 14 0 Q14847;Q14847-2;C9J9W2;F6S2S5 Q14847 LASP1 LIM and SH3 domain protein 1 1 QSFT(0.001)MVADT(0.999)PENLR;QSFT(0.002)MVADT(0.998)PENLR;QSFTMVADT(1)PENLR;QSFTMVADT(1)PENLR;QSFTMVADT(1)PENLR 245.04 1.3881e-34 83181900.0 216312.0 192165.0 233929.0 198481.0 162280.0 169769.0 139793.0 126498.0 166240.0 113271.5 True False 213227.35121323777 191720.05374908244 214696.26061205374 213077.95485320585 152735.00945475552 162508.37562086832 147030.79752759784 132375.55888365326 147516.30061519306 132850.32785021322 1.6050193828173946 1.4431281943484848 1.6160762572909915 1.6038948364015186 1.1496773242965723 1.2232440691007862 1.1067401933202068 0.996426286827871 1.110394705096366 1.0 17.019442262576057 -6.310309021079725 4.71923994423063 1.0992635274709817 1.5626968318150067 0.9010622678840009 0.07624746600113741 0.06603380423712399 3.3174983204310164 0.02539446384675807 0.02954280717259169 4.894304425144617e-07 6.310309021079725 0.4634333043440251 QSGEAFVELGSEDDVK ddPTM_PC-9_Lapatinib_30min_R1 1 QSGEAFVELGSEDDVK 16 0 P52597;A0A1B0GW42 P52597 HNRNPF Heterogeneous nuclear ribonucleoprotein F;Heterogeneous nuclear ribonucleoprotein F, N-terminally processed 0 89.624 0.017093 3331700.0 14837.0 18522.0 23873.0 20380.0 18311.0 18698.0 16755.0 14929.0 20681.0 19481.0 False True 14625.421659227439 18479.113446988293 21910.254092444935 21878.813185687006 17233.982980811114 17898.33012716687 17622.491917155377 15622.65584099398 18351.687999415364 22848.264893199186 0.6401108236267303 0.808775350485744 0.9589460816767118 0.9575700075238213 0.7542797258946708 0.7833562071706518 0.7712835963487421 0.68375677164195 0.8031983209752512 1.0 14.479796990127205 QSGLSSLVNGKS(ph)PIR ddPTM_PC-9_AZD4547_30min_R2 1 QSGLSSLVNGKSPIR 15 1 H0Y612;Q9UPN9-2;Q9UPN9 H0Y612 TRIM33 E3 ubiquitin-protein ligase TRIM33 1 QS(0.002)GLS(0.165)S(0.244)LVNGKS(0.589)PIR 53.037 0.038852 58108000.0 49260.0 47376.0 81855.0 79972.0 80561.0 83328.0 74076.0 74056.0 60720.0 81471.0 True False 64923.65532834887 62689.36551182542 80769.54921689302 61535.69095508333 69376.4957340826 78117.4869872618 80668.62049577318 62612.34683758445 63929.53523766313 78618.72508784253 0.825803970438444 0.797384661755595 1.027357657182145 0.7827103643098775 0.8824423908752861 0.9936244437947743 1.0260738825978195 0.7964050137880795 0.8131591445451853 1.0 16.262585348191124 -6.534048461946473 24.857096219256118 0.9214629580136798 0.8618540563118015 0.10259140906808462 0.0942332613112367 598.810194934096 1332582.2056127558 0.032502242898090276 0.032529897719828386 2.923826096447516e-07 6.534048461946473 -0.05960890170187838 QSGLSSLVNGKS(ph)PIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSGLSSLVNGKSPIR 15 1 H0Y612;Q9UPN9-2;Q9UPN9 H0Y612 TRIM33 E3 ubiquitin-protein ligase TRIM33 1 QS(0.003)GLS(0.005)S(0.005)LVNGKS(0.987)PIR 50.493 0.046254 40668000.0 27985.0 26638.0 31045.0 42320.0 41532.0 41922.0 46045.0 42759.0 40597.0 41738.0 True False 32722.30777105524 29282.444595591012 31785.23053881815 39948.94760329119 33394.102739956594 39723.53652053679 41683.28426306836 41636.62155690542 41190.654323021634 49304.7690021738 0.663674294257672 0.5939069422331129 0.6446684810026545 0.8102451022847279 0.6772996490153778 0.8056733116178968 0.8454209421654644 0.8444745285201457 0.8354294149761776 1.0 15.589439577532577 -5.19076302993152 0.13901751963792522 1.0954692554533076 0.2230406555837357 0.8260190638071583 0.048978059538608475 9.750301791837158 0.2669364828599271 0.33364201808653476 1.6549413080213409 6.445208483577903e-06 5.19076302993152 -0.872428599869572 QSGLSSLVNGKS(ph)PIR ddPTM_PC-9_Lapatinib_30min_R1 2 QSGLSSLVNGKSPIR 15 1 H0Y612;Q9UPN9-2;Q9UPN9 H0Y612 TRIM33 E3 ubiquitin-protein ligase TRIM33 1 QSGLSSLVNGKS(1)PIR;QSGLS(0.046)S(0.012)LVNGKS(0.942)PIR 108.47 0.00034524 82653000.0 226414.0 143193.0 158240.0 141547.0 139305.0 128119.0 116142.0 109903.0 148023.0 134830.0 True False 223185.2948407573 142861.44540625162 145230.1180240645 151956.83856695017 131111.35378416747 122639.64902997614 122155.2644728296 115009.49460062696 131351.09098870758 158135.18585031814 1.4113575902836193 0.903413396822869 0.9183921797235635 0.9609299647630853 0.8291093034049366 0.7755367559125008 0.7724736516796135 0.727285923004438 0.8306253303615625 1.0 17.270798884535992 -2.145370140539367 1.0686516524659022 0.826022584013733 199.9996582895222 0.7914726037085695 0.08485599002072931 243.47367076797232 1.0775628227068936 0.026742584450579882 117874.42285772129 0.007155333154667716 2.145370140539367 199.17363570550845 QSGT(ph)PPGMGAPGVPGAAGVGGAGGR ddPTM_PC-9_AZD4547_30min_R2 1 QSGTPPGMGAPGVPGAAGVGGAGGR 25 0 A0A075B785;A0A2R8Y566;Q9P260;Q9P260-2 A0A075B785 KIAA1468 LisH domain and HEAT repeat-containing protein KIAA1468 1 QS(0.037)GT(0.963)PPGMGAPGVPGAAGVGGAGGR 111.99 0.00036486 0.0 5736.6 8077.4 7856.7 5862.1 6199.5 8765.7 8012.5 12082.0 7752.4 6360.7 True False 7560.719471307475 10688.261587833891 7752.515024523414 4510.683413542166 5338.8064361594825 8217.579393292048 8725.596977730747 10215.004516739968 8162.176037161725 6138.013829046398 1.2317859949302377 1.7413225003265298 1.2630331635678058 0.734876710801244 0.8697938103194074 1.3388010555474312 1.4215668489437658 1.6642198602421479 1.3297747878208674 1.0 12.58355618088587 -6.984078952243554 24.920717759723413 1.4050909584695643 1.1735131758175923 0.07861866929874017 0.2925157829896975 561.118678726635 878298.160176659 0.11353332893370648 0.10009903218757214 1.0373398162520787e-07 6.984078952243554 -0.23157778265197204 QSGT(ph)PPGMGAPGVPGAAGVGGAGGREPSTASGGGQLNR ddPTM_PC-9_Lapatinib_30min_R1 1 QSGTPPGMGAPGVPGAAGVGGAGGREPSTASGGGQLNR 38 1 A0A075B785;A0A2R8Y566;Q9P260;Q9P260-2 A0A075B785 KIAA1468 LisH domain and HEAT repeat-containing protein KIAA1468 1 QS(0.086)GT(0.789)PPGMGAPGVPGAAGVGGAGGREPS(0.071)T(0.038)AS(0.016)GGGQLNR 40.918 0.025098 7805000.0 7984.7 8997.7 8934.8 8346.8 6073.9 8425.1 5477.5 6555.7 9962.0 5445.0 True False 7870.836713785348 8976.866378467035 8200.215233325389 8960.651516108559 5716.645143746851 8064.778112867351 5761.098148386665 6860.301754759476 8839.974655489377 6386.160994993555 1.2324832900322602 1.4056749251239469 1.2840602107829675 1.4031358625523662 0.8951614511798917 1.2628523019055975 0.9021222848755444 1.0742450370633665 1.3842392420766554 1.0 12.640733208342262 -6.241764777163892 24.974212838365805 1.0897540159972217 1.33327129712945 0.3945578849062029 0.14857864787694045 844.4273285847061 1071884.74813541 0.04238005976350057 0.05463546760464283 5.731063531443416e-07 6.241764777163892 0.24351728113222837 QSHAASAAPQAS(ph)SPPDYTMAWAEYYR ddPTM_PC-9_AZD4547_30min_R2 4 QSHAASAAPQASSPPDYTMAWAEYYR 26 0 Q96I24 Q96I24 FUBP3 Far upstream element-binding protein 3 1 QSHAASAAPQAS(0.671)S(0.219)PPDY(0.09)T(0.02)MAWAEYYR;QSHAASAAPQAS(0.528)S(0.465)PPDY(0.005)T(0.002)MAWAEYYR;QSHAASAAPQAS(0.794)S(0.205)PPDY(0.001)TMAWAEYYR;QSHAASAAPQAS(0.823)S(0.177)PPDYTMAWAEYYR 107.49 4.933599999999999e-10 72668100.0 37541.8 32350.0 81068.0 113236.0 87135.9 74106.0 60771.5 93585.6 59200.9 68938.1 True False 49479.31148205053 42806.50486127056 79992.98535110983 87131.18967876033 75038.58436011747 69472.14010510282 66180.04577000483 79124.09590314697 62330.13871296724 66524.59810212452 0.7437746772418361 0.6434688232998659 1.2024572509000273 1.3097589788517296 1.1279825282810847 1.044307550696562 0.9948206777350123 1.18939607544386 0.9369487451435902 1.0 16.021600269008545 -5.257908004156356 24.999629201210336 1.1101171903920242 0.6936217115931251 0.6882979958325989 0.10943299698533385 164.26543947374583 1162869.983285967 0.02936975611009694 0.07149144923132876 5.521943972701739e-06 5.257908004156356 -0.41649547879889903 QSHAASAAPQAS(ph)SPPDYTMAWAEYYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QSHAASAAPQASSPPDYTMAWAEYYR 26 0 Q96I24 Q96I24 FUBP3 Far upstream element-binding protein 3 1 QSHAASAAPQAS(0.617)S(0.38)PPDY(0.002)T(0.001)MAWAEYYR;QSHAASAAPQAS(0.82)S(0.178)PPDY(0.001)T(0.001)MAWAEYYR;QSHAASAAPQAS(0.77)S(0.228)PPDY(0.001)TMAWAEYYR;QSHAASAAPQAS(0.801)S(0.153)PPDY(0.021)T(0.025)MAWAEYYR 105.7 6.3255e-10 49012200.0 88190.0 86443.0 141034.0 158834.0 178502.0 160766.0 148614.0 144138.0 143504.0 117278.0 True False 103118.82516810288 95024.48975811529 144396.78543442374 149935.04592677578 143525.81448732852 152335.1479476318 134536.20604781536 140354.53022683473 145602.47451710486 138539.57302786267 0.7443275803034554 0.6859014192212376 1.0422782622939302 1.0822542804908262 1.0359914596998434 1.0995785869572055 0.9711030798453365 1.0131006409165635 1.050981112001996 1.0 17.07993860707446 -5.2642194439642696 24.940382073679217 1.038853233912741 0.7151144796496934 0.9210068836240993 0.03769335797099068 51.591513808493666 462840.19184242364 0.009913849607705168 0.02223945171775675 5.4422759146620825e-06 5.2642194439642696 -0.32373875426304755 QSHAASAAPQAS(ph)SPPDYTMAWAEYYR ddPTM_PC-9_Lapatinib_30min_R1 2 QSHAASAAPQASSPPDYTMAWAEYYR 26 0 Q96I24 Q96I24 FUBP3 Far upstream element-binding protein 3 1 QSHAASAAPQAS(0.497)S(0.497)PPDY(0.005)T(0.001)MAWAEYYR;QSHAASAAPQAS(0.821)S(0.176)PPDY(0.002)T(0.001)MAWAEYYR 97.395 2.5879999999999997e-09 33485000.0 66511.0 57672.0 79320.0 60074.0 76755.0 75643.0 57076.0 66885.0 82483.0 61934.0 True False 65562.54094337647 57538.464027357135 72798.61578405448 64492.04236098925 72240.42180613607 72407.92522244538 60031.11600498716 69992.72127569723 73192.89595550399 72639.20937813245 0.9025778433529267 0.7921130271095531 1.0021944953322965 0.8878406429958219 0.9945100232311115 0.9968159874306576 0.8264285434673126 0.9635666725300024 1.0076224202068231 1.0 16.148460879638975 -1.522879762687224 0.2902266469478022 0.9747322571904858 5.4209643514312776e-08 0.2113846894008663 0.06740713456342176 86.36938114476689 1.2257549669413303 0.07195710516407339 43.21512122540445 0.029999929720104422 1.522879762687224 -0.9747322029808423 QSHS(ph)ESPSLQSK ddPTM_PC-9_AZD4547_30min_R2 1 QSHSESPSLQSK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QS(0.009)HS(0.75)ES(0.207)PS(0.034)LQSK 153.41 0.00021429 90662000.0 11547.0 9340.9 13527.0 20333.0 17272.0 18267.0 14651.0 19164.0 14491.0 15965.0 True False 15218.705807479597 12360.163253744733 13347.623141615206 15645.540991718466 14874.080936421733 17124.761602298255 15954.910617252206 16202.644144910175 15256.964676037169 15406.070209367796 0.9878382741775206 0.8022917645947782 0.8663872720441756 1.0155439238622357 0.9654688531392916 1.1115593639113364 1.0356249452602575 1.0517051996204727 0.9903216374257491 1.0 13.91121128471922 -5.789673078040828 6.029105063604998 1.0288872811213348 0.8767778925124593 0.557587733073404 0.056440123722625975 0.11336585869420004 12.315604519875071 0.015669905561070868 0.024305074786481848 1.6230313998778322e-06 5.789673078040828 -0.15210938860887546 QSHS(ph)ESPSLQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSHSESPSLQSK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QSHS(0.77)ES(0.225)PS(0.006)LQSK 254.94 2.1912999999999998e-39 123420000.0 28132.0 33108.0 38050.0 36685.0 37912.0 42749.0 37745.0 37554.0 36514.0 28142.0 True False 32894.191967672894 36394.74343685065 38957.25630542859 34629.658384374714 30483.415753569156 40507.16718468651 34169.52034986459 36568.247291752064 37047.94817229875 33243.921828050574 0.9894798856107709 1.0947788779283398 1.1718610249094383 1.041683907316702 0.9169620814066481 1.2184834086123781 1.0278426392229396 1.099997993043543 1.1144277249815457 1.0 15.020802968280023 -6.771662040898646 24.99876185091281 1.0943809322448736 1.0529233797923703 0.07549755756869492 0.08228299045281097 732.966318525082 1792404.3304273346 0.029204146048913186 0.026043763596837244 1.691756910239805e-07 6.771662040898646 -0.04145755245250338 QSHS(ph)ESPSLQSK ddPTM_PC-9_Lapatinib_30min_R1 1 QSHSESPSLQSK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QS(0.004)HS(0.495)ES(0.492)PS(0.009)LQSK 102.39 0.0013732000000000002 260370000.0 77009.0 71137.0 111610.0 103980.0 100610.0 98552.0 74973.0 92647.0 82434.0 73337.0 True False 75910.83753827898 70972.28664714424 102433.85662705897 111627.03606711165 94692.31760687058 94337.16069593276 78854.73509429354 96951.717844502 73149.41485149675 86013.20273458993 0.8825486684005511 0.8251324725826419 1.1909085276493898 1.297789554605449 1.1009044495071496 1.0967753518843844 0.9167747809323507 1.1271725126160566 0.850444030984559 1.0 16.392270505152318 -8.259951841634312 24.988268804857306 0.9252220192678299 1.058076802495377 0.11828846738298471 0.14122160815572382 306.2562792921186 5144863.599373671 0.1177658161529182 0.03901053063477287 5.496018151287106e-09 8.259951841634312 0.13285478322754718 QSHSES(ph)PSLQSK ddPTM_PC-9_AZD4547_30min_R2 6 QSHSESPSLQSK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QSHS(0.002)ES(0.756)PS(0.24)LQS(0.002)K;QS(0.025)HS(0.009)ES(0.96)PS(0.006)LQSK;QS(0.015)HS(0.223)ES(0.743)PS(0.02)LQSK;QSHS(0.006)ES(0.987)PS(0.006)LQSK;QS(0.006)HS(0.003)ES(0.989)PS(0.002)LQSK;QS(0.013)HS(0.007)ES(0.966)PS(0.015)LQSK 153.41 0.00021429 776869900.0 200843.0 167385.0 273098.0 347123.0 323850.0 306204.0 247081.0 345220.0 245697.0 279785.0 True False 264706.89620608126 221488.92785792184 269476.5420809365 267099.1553468886 278889.01755790826 287057.01547435933 269070.730340679 291874.1813664106 258684.04181963342 269989.81230992556 0.9804329057506068 0.8203603164243516 0.9980989274202692 0.9892934591186768 1.0329612631374667 1.0632142487837357 0.9965958642610132 1.0810562771582048 0.9581251959340078 1.0 18.04254544464905 -5.432399890939038 6.744953543407995 1.0203386091531546 0.9006408497919138 0.46584181942958547 0.04932714594537301 0.18509968266886626 11.671097996635844 0.012080761357129034 0.025319180579421587 3.694878050404906e-06 5.432399890939038 -0.11969775936124072 QSHSES(ph)PSLQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 QSHSESPSLQSK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QS(0.065)HS(0.114)ES(0.7)PS(0.121)LQSK;QS(0.057)HS(0.258)ES(0.642)PS(0.043)LQSK;QS(0.296)HS(0.13)ES(0.538)PS(0.037)LQSK;QS(0.001)HS(0.026)ES(0.787)PS(0.187)LQSK;QS(0.048)HS(0.025)ES(0.887)PS(0.04)LQSK;QSHS(0.001)ES(0.992)PS(0.006)LQSK;QS(0.029)HS(0.024)ES(0.943)PS(0.003)LQSK;QS(0.027)HS(0.05)ES(0.92)PS(0.003)LQSK 188.0 7.924500000000001e-18 366491800.0 225387.0 236436.9 262593.0 318591.0 346394.0 309706.0 306326.0 304738.0 269434.0 236252.0 True False 263540.5675038352 259908.79287496445 268854.21300949773 300741.37915595784 278520.5823101351 293464.47215374676 277308.58367181383 296738.9503966 273373.96253095084 279082.6174301971 0.9443102187105967 0.9312969588296616 0.9633499050751249 1.077606989375388 0.9979861335498528 1.0515326065663935 0.9936433383966418 1.0632656133477 0.9795449284809934 1.0 18.090332743848975 -5.578119212610992 7.579276399296398 1.0248029737436652 0.9400701909328805 0.5769951305871579 0.03071865022221116 0.1354729192308723 15.776363767703089 0.007612316299718208 0.013277378763767242 2.6416835231090264e-06 5.578119212610992 -0.08473278281078478 QSHSES(ph)PSLQSK ddPTM_PC-9_Lapatinib_30min_R1 4 QSHSESPSLQSK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QS(0.004)HS(0.006)ES(0.951)PS(0.036)LQS(0.003)K;QS(0.104)HS(0.031)ES(0.816)PS(0.049)LQSK;QSHS(0.273)ES(0.671)PS(0.056)LQSK;QS(0.09)HS(0.196)ES(0.711)PS(0.002)LQSK 111.88 0.0010206 418849300.0 233084.0 203091.0 278855.0 216235.0 253201.0 235957.0 215746.0 221711.0 270800.0 198090.0 True False 229760.17941762914 202620.755267374 255928.61831142838 232137.6432388138 238308.21499231918 225865.6691526322 226916.27222671444 232012.50245579853 240299.65234958075 232329.59256166674 0.9889406548872779 0.8721263315330475 1.101575634380273 0.9991738059679074 1.0257333659682872 0.9721777870061094 0.9766998242657553 0.9986351712566102 1.0343049703657468 1.0 17.825813400959227 -5.246452329051907 24.99844824715164 1.0106186337580527 0.9305335060591682 0.36693453097597606 0.043475282782170194 869.2065928700397 1449834.236559787 0.010727923833613914 0.028159744702165715 5.669538005936448e-06 5.246452329051907 -0.08008512769888454 QSHSESPS(ph)LQSK ddPTM_PC-9_AZD4547_30min_R2 1 QSHSESPSLQSK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QS(0.003)HS(0.003)ES(0.392)PS(0.602)LQSK 67.32600000000001 0.021055 5007700.0 23217.0 21993.0 26694.0 42424.0 43499.0 32720.0 34108.0 42458.0 34225.0 36860.0 True False 30599.523056400238 29101.807153444282 26340.020118450244 32643.802244266175 37459.914697395165 30674.013227524974 37143.54592404874 35897.09168777899 36034.063628277676 35569.54261931082 0.8602731663967941 0.8181664708177837 0.7405217548158789 0.9177459095733143 1.0531458078704126 0.8623673786255535 1.0442514350432885 1.0092086949774368 1.013059515944258 1.0 15.118354802779841 -5.969007884305253 5.54497043019231 0.9927793702709721 0.8088576771793347 0.6974755393319606 0.05615912095712834 0.09986641217450894 8.483663971885056 0.01593620748850747 0.023451730276065338 1.0739699150096943e-06 5.969007884305253 -0.18392169309163742 QSHSESPS(ph)LQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSHSESPSLQSK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QS(0.001)HSES(0.396)PS(0.602)LQSK 89.484 0.0042313 5587200.0 47238.0 49844.0 51444.0 55516.0 61643.0 63042.0 56648.0 58276.0 51128.0 43044.0 True False 55234.460406971884 54792.18291247988 52670.62006245643 52405.61850530043 49564.496657978045 59735.966540901696 51281.89134399603 56746.31674852592 51875.650275326974 50847.53646388348 1.086276037113507 1.077577926541205 1.0358539218486595 1.0306422326384217 0.9747669229399784 1.174805520486358 1.0085422993977509 1.1160091657308173 1.0202195402755403 1.0 15.633890257517479 QSHSESPS(ph)LQSK ddPTM_PC-9_Lapatinib_30min_R1 1 QSHSESPSLQSK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QSHS(0.003)ES(0.247)PS(0.75)LQSK 89.23200000000001 0.0043092 4010200.0 30447.0 34746.0 36858.0 40382.0 41152.0 38770.0 38588.0 39938.0 43243.0 32688.0 True False 30012.820196704033 34665.54777178785 33827.67751599446 43351.826990403 38731.5202679449 37111.89747728419 40585.89782746592 41793.66528083715 38372.51797102259 38338.077245977875 0.7828462550205941 0.9042067381046003 0.8823519577926509 1.1307772873495143 1.010262460984746 0.9680166597603085 1.058631541875874 1.0901346202807238 1.00089834252312 1.0 15.226490363471221 -5.642481381925444 6.6613958961484325 1.0372912578999507 0.8560074578697999 0.7108673714087032 0.05296182809437298 0.11583406149444525 6.259222632460063 0.014513991483816694 0.025293517734224055 2.277815889050197e-06 5.642481381925444 -0.18128380003015077 QSHSGSIS(ph)PYPK ddPTM_PC-9_AZD4547_30min_R2 5 QSHSGSISPYPK 12 0 Q9UQ35;Q9UQ35-2;I3L4D8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QSHSGS(0.004)IS(0.996)PYPK;QSHSGSIS(1)PYPK;QSHSGSIS(1)PYPK;QSHSGSIS(1)PYPK;QSHS(0.01)GS(0.167)IS(0.824)PYPK 156.72 0.00011099 1015416300.0 468371.0 519568.0 756957.0 807688.0 740828.0 870650.0 812328.0 913057.0 805245.0 760100.0 True False 617303.2352779952 687508.1952939918 746919.2555930832 621488.0102552059 637976.8198221069 816208.117865054 884623.6183121459 771965.0206125672 847808.6067597516 733489.1303564357 0.8415983410388366 0.937312043001783 1.0183099171900765 0.8473036402778003 0.8697836047169301 1.1127746602985398 1.2060487084277134 1.0524559787783554 1.1558570831823545 1.0 19.48441606106205 -6.768340486424521 24.98506242010624 1.1149946694750057 0.9081026747381005 0.6724101290738513 0.07048893454201202 95.31549036451631 345082.0805717064 0.02452702492005126 0.022102481162339933 1.704745346363647e-07 6.768340486424521 -0.20689199473690523 QSHSGSIS(ph)PYPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 QSHSGSISPYPK 12 0 Q9UQ35;Q9UQ35-2;I3L4D8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QSHSGS(0.001)IS(0.999)PYPK;QSHSGSIS(1)PYPK;QSHSGSIS(1)PYPK;QSHS(0.001)GS(0.032)IS(0.967)PYPK;QS(0.001)HS(0.013)GS(0.08)IS(0.905)PYPK 204.17 9.554999999999999e-08 282021000.0 101768.5 138600.0 152519.0 168474.0 182308.0 131163.0 166842.0 130139.0 132342.0 119905.0 True False 118995.89703050353 152359.29202451074 156155.63139152885 159034.94798007762 146586.05610892817 124284.58138073485 151037.51792852342 126722.98914366812 134277.2513835339 141642.82733254234 0.8401124100066895 1.0756583647317968 1.1024605645926147 1.1227885730260303 1.0348992523622842 0.8774505827177919 1.0663266243191027 0.8946657697403475 0.9479989485686001 1.0 17.11189802120208 -6.556212391994021 23.74482379269755 0.9573703148360558 1.0474291664554536 0.1599056858880893 0.08751013288555773 183.80921304749157 130932.43397851575 0.02891087163196538 0.028911079043069055 2.778354179567173e-07 6.556212391994021 0.09005885161939775 QSHSGSIS(ph)PYPK ddPTM_PC-9_Lapatinib_30min_R1 7 QSHSGSISPYPK 12 0 Q9UQ35;Q9UQ35-2;I3L4D8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 QSHSGS(0.002)IS(0.997)PYPK;QSHSGSIS(1)PYPK;QSHSGSIS(1)PYPK;QSHSGS(0.01)IS(0.99)PYPK;QSHSGSIS(1)PYPK;QSHSGSIS(1)PYPK;QSHS(0.001)GS(0.003)IS(0.995)PYPK 209.53 3.7065e-08 813193400.0 420526.0 577857.0 702567.7 581923.0 728562.6 717092.3 633458.9 663272.3 717978.6 560519.8 True False 414529.22212497593 576519.007619927 644805.2956957506 624719.5586582221 685709.9802771828 686423.9339527969 666256.3023037985 694090.3524525758 637112.2894181642 657404.9005843144 0.6305538972352263 0.8769618344912027 0.9808343307490331 0.9502812621307798 1.0430557783608096 1.0441417965437887 1.0134641553654633 1.0558034353495915 0.9691322484086843 1.0 19.326422685376386 -4.319013494234857 1.0612129743929424 1.0190584941599845 2.732151713868508e-22 0.9367335847915238 0.030133960743892352 0.8996926501377727 0.42426628436092706 0.009357096280240345 1.3098228348432757 4.7971854277091814e-05 4.319013494234857 -1.0190584941599845 QSIS(ph)FSGLPSGR ddPTM_PC-9_AZD4547_30min_R2 1 QSISFSGLPSGR 12 0 M0QY76;P26651 M0QY76 ZFP36 Tristetraprolin 1 QS(0.013)IS(0.974)FS(0.013)GLPSGR 84.195 0.010341 6970800.0 12298.0 9352.2 18547.0 28059.0 18602.0 14078.0 13610.0 23235.0 15557.0 15713.0 True False 16208.508185709183 12375.115757761188 18301.054661605493 21590.431057228558 16019.433393892834 13197.70043450785 14821.26363393642 19644.564637183666 16379.311259755033 15162.89265266498 1.0689588429461334 0.8161447845893823 1.206963280742409 1.4238992223844502 1.056489270276362 0.8703946362232055 0.9774694033286244 1.2955684042075575 1.0802233871171185 1.0 13.888257384876626 -10.432790113930619 5.330926307538884 0.9999998625241713 1.0892724322708753 0.022552093328581102 0.17463093487811443 3.0758549070043453e-07 6.242866697078618e-08 0.18157700533740764 0.04403882489010672 3.691559613573972e-11 10.432790113930619 0.08927256974670406 QSIS(ph)FSGLPSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QSISFSGLPSGR 12 0 M0QY76;P26651 M0QY76 ZFP36 Tristetraprolin 1 QS(0.005)IS(0.993)FS(0.003)GLPSGR;QS(0.139)IS(0.858)FS(0.003)GLPSGR;QS(0.047)IS(0.936)FS(0.015)GLPS(0.002)GR 85.163 0.0098152 12878600.0 28790.5 35216.0 30119.6 39474.0 46329.0 47898.0 49355.0 44841.0 42709.0 43370.0 True False 33664.16301170505 38712.01174556399 30837.765493219085 37262.39975643469 37251.16502550922 45386.14456039002 44679.73710074361 43663.97126296677 43333.53832751016 51232.637683268935 0.6570843222990795 0.7556123107478847 0.6019164128121748 0.7273176131746089 0.7270983246227501 0.8858834253464914 0.8720951940238417 0.8522686560256126 0.8458189991194152 1.0 15.644775549589264 -6.671572367780708 2.8761116179504405 0.882892121194907 0.6865379452180346 0.7588973684340858 0.05578529964405111 0.13255664318568838 2.2177907106836208 0.019283978102493597 0.01885883162157954 2.1302355704799855e-07 6.671572367780708 -0.19635417597687244 QSIS(ph)FSGLPSGR ddPTM_PC-9_Lapatinib_30min_R1 2 QSISFSGLPSGR 12 0 M0QY76;P26651 M0QY76 ZFP36 Tristetraprolin 1 QS(0.002)IS(0.933)FS(0.061)GLPS(0.004)GR;QS(0.022)IS(0.842)FS(0.135)GLPSGR 94.339 0.0049396 13871200.0 21637.7 20778.9 22228.4 19068.4 29239.0 26295.0 30190.0 28066.0 33374.0 31536.0 True False 21329.142430131786 20730.78773370181 20400.866756105344 20470.753746317678 27519.21950608576 25170.424146638834 31753.090479195485 29370.048819970347 29615.06867619981 36986.95558092136 0.5766666138138117 0.5604891618707645 0.5515692339552416 0.5534587376766126 0.7440249967553626 0.6805216528721888 0.8584942983405314 0.7940650523591627 0.8006895461132756 1.0 15.174728935781479 -7.198070631665322 0.34050334137878 0.9963613005354062 0.47782812068024266 0.872486820337973 0.05213580624740171 0.5385607631227131 0.1556573027918579 0.06909624207039093 0.10054569848038725 6.337666299729853e-08 7.198070631665322 -0.5185331798551636 QSLGELIGTLNAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSLGELIGTLNAAK 14 0 P60174;P60174-3 P60174 TPI1 Triosephosphate isomerase 0 ; 145.43 9.2401e-08 1713200.0 16877.5 17890.699999999997 18798.1 16660.9 16830.8 18804.4 20006.0 17958.699999999997 15827.1 19432.3 False True 19734.52740418028 19666.770460482774 19246.317996191236 15727.443788366596 13532.92556090873 17818.26416074572 18110.88684910296 17487.30315381551 16058.541395568533 22955.222163997834 0.859696641713676 0.856744941084798 0.838428740035306 0.6851357689333527 0.5895358129939294 0.776218327727242 0.7889658710211674 0.7618006494941261 0.6995593978939654 1.0 14.486534774280928 -5.642115638498179 6.751067567766582 0.742743079259099 0.8553543607787741 0.14996025786419775 0.09926265937912306 0.34088753551623413 18.681026014291785 0.026416932213659504 0.04602030047250809 2.2797349718877133e-06 5.642115638498179 0.11261128151967514 QSLGELIGTLNAAK ddPTM_PC-9_Lapatinib_30min_R1 1 QSLGELIGTLNAAK 14 0 P60174;P60174-3 P60174 TPI1 Triosephosphate isomerase 0 91.307 0.02115 3528600.0 26366.0 24675.0 24299.0 25322.0 26117.0 22387.0 22596.0 21023.0 17422.0 27859.0 False True 25990.016005067773 24617.866553527485 22301.230016852485 27184.264351715745 24580.849407997594 21429.560196645874 23765.91031692288 21999.805328234743 15459.750898206777 32674.391030215873 0.7954246486501714 0.7534300036613365 0.6825293238435344 0.8319746288944423 0.7522970936249823 0.6558518619927373 0.7273558761950663 0.6733042188266116 0.473145800449969 1.0 14.995872727555632 -6.668197817193889 6.781215519357737 0.6870597206846668 0.7628092009689803 0.03912617799637064 0.12605424375779253 0.611471068696528 37.585087772333495 0.039853491668701 0.03973038156510496 2.1468523796215272e-07 6.668197817193889 0.0757494802843135 QSLPAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 QSLPASPR 8 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;H0YF21 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 QS(0.001)LPAS(0.999)PR 72.152 0.033460000000000004 28775000.0 87301.0 63832.0 145400.0 182810.0 172780.0 146530.0 100130.0 213990.0 103650.0 138790.0 True False 115060.90202639431 84464.44569720632 143471.90099732776 140665.9788863449 148792.47939989244 137367.45593610127 109041.37602248727 180922.76250100866 109128.72739433116 133931.00434438846 0.8591057954775594 0.6306564048457035 1.0712374009262706 1.0502868964130083 1.1109636646738599 1.0256583724473263 0.8141608177752455 1.3508654204950648 0.8148130295037507 1.0 17.03113045030541 -5.2713223428640825 24.94651998410753 1.0380675792824021 0.7448810980333722 0.35776823037212335 0.15234185968780273 569.4492149855485 1437402.5081097672 0.037212568185706806 0.07896602167244621 5.353991250611868e-06 5.2713223428640825 -0.2931864812490299 QSLPAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 QSLPASPR 8 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;H0YF21 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 QS(0.001)LPAS(0.999)PR 72.289 0.033087 22911000.0 81795.0 72351.0 91008.0 61591.0 65714.0 82114.0 94391.0 74509.0 70621.0 68300.0 True False 80628.58830063402 72183.47570473218 83525.67354103914 66120.60760155303 61848.83171869494 78602.17563708307 99278.10412129002 77970.9601484774 62666.919307901546 80105.56399597041 1.0065291882183105 0.9011043940513702 1.0426950310872385 0.8254184141925412 0.7720915830741314 0.9812324102859701 1.2393409292553517 0.973352614462581 0.782304201878585 1.0 16.289614832802805 -6.985402161392293 24.930369697988233 1.012779963930565 0.9083028760955952 0.10048898785197591 0.12623455133145733 510.1186543754818 871183.8132532899 0.0469168753726221 0.04135993860538098 1.034184057503847e-07 6.985402161392293 -0.10447708783496978 QSLS(ph)PMSQRPVLK ddPTM_PC-9_Lapatinib_30min_R1 1 QSLSPMSQRPVLK 13 1 Q9NSV4-1;Q9NSV4-7;Q9NSV4-6;Q9NSV4-5;Q9NSV4-4;Q9NSV4 Q9NSV4-1 DIAPH3 Protein diaphanous homolog 3 1 QS(0.232)LS(0.745)PMS(0.023)QRPVLK 116.87 0.0012902 11063000.0 27119.0 21940.0 18105.0 19003.0 21479.0 18339.0 16856.0 18703.0 22752.0 12355.0 True False 26732.27808698448 21889.199277989577 16616.476787321055 20400.54401214967 20215.64744933877 17554.683720297 17728.721202958564 19572.00965865834 20189.43017081855 14490.545287997315 1.8448082909017325 1.5105849257529773 1.1467116286565608 1.4078520584762033 1.395092251365007 1.2114577727339042 1.2234681891262897 1.3506744756437883 1.393282983459683 1.0 13.82282426495414 -4.896183101886972 2.974098948469415 1.2851405172594703 1.873987221759521 0.6724767131374545 0.12497590309392204 0.1788459187227039 2.6639332370011926 0.030995126304805217 0.22210541441556647 1.2700385343218999e-05 4.896183101886972 0.5888467045000507 QSLS(ph)SADNLESDAQGHQVAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSLSSADNLESDAQGHQVAAR 21 0 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 1 QS(0.184)LS(0.674)S(0.142)ADNLESDAQGHQVAAR 115.06 0.00015846 0.0 15832.0 14533.0 15502.0 22165.0 22140.0 16002.0 19958.0 13390.0 18358.0 16195.0 True False 18512.044903746526 15975.740194749016 15871.626471662381 20923.166909899566 17801.82593331982 15162.826950088978 18067.43375659287 13038.526687877722 18626.451020076143 19131.025300450547 0.9676452052630214 0.8350697332658265 0.8296275930014371 1.0936772379579056 0.930521268658851 0.7925778525697671 0.9444048854071282 0.6815383118839249 0.9736253403855715 1.0 14.223626574521347 -6.643894813824943 21.921236151311685 0.8625078209077035 0.929348989256584 0.04434772218080241 0.11086187258558511 9.402163738948872 1731.1766408833453 0.03594370217509257 0.035943680235112366 2.2704146800018553e-07 6.643894813824943 0.06684116834888054 QSMAFS(ph)ILNTPK ddPTM_PC-9_AZD4547_30min_R2 1 QSMAFSILNTPK 12 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 QS(0.009)MAFS(0.892)ILNT(0.099)PK 66.568 0.034299 6587500.0 34506.0 29540.0 38339.0 44155.0 51968.0 40575.0 40793.0 35949.0 36707.0 46547.0 True False 45478.190230613225 39088.22731381549 37830.599809742416 33975.74693794958 44753.14023297621 38037.838835783165 44423.49797348773 30393.908075838863 38647.25708117428 44917.40369780413 1.0124848385401337 0.8702245476340029 0.8422258789546162 0.7564049597909094 0.9963429884342146 0.8468396591150862 0.9890041346191932 0.6766621748737611 0.8604071896315685 1.0 15.454986919475104 QSMAFSILNT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 QSMAFSILNTPK 12 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 QS(0.005)MAFS(0.061)ILNT(0.933)PK;QSMAFSILNT(1)PK;QSMAFSILNT(1)PK;QSMAFS(0.138)ILNT(0.862)PK 156.72 0.00094095 137202000.0 692835.0 574638.0 770230.0 909600.0 951380.0 912530.0 822160.0 806410.0 784720.0 858300.0 True False 913142.1181367538 760378.4958414466 760016.2469406577 699905.773179911 819297.3090141785 855469.3548445415 895330.6472650368 681797.8639583071 826198.6971623689 828251.1782461865 1.1024941975577058 0.9180530204032312 0.9176156544081042 0.8450404799446882 0.9891894277156746 1.0328622250269408 1.0809892829381667 0.8231776565679112 0.9975219098532843 1.0 19.659708825080827 -4.7530995421864874 24.982904571892448 0.9531944896128064 1.1024944769297989 0.24506621295324627 0.07696247072517363 477.0730544893742 1429014.1737101488 0.01986749164453775 0.22136299369180779 1.7656330835125786e-05 4.7530995421864874 0.14929998731699246 QSMAFSILNT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QSMAFSILNTPK 12 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 QSMAFSILNT(1)PK;QSMAFSILNT(1)PK;QSMAFSILNT(1)PK 122.96 0.00092152 82763800.0 237081.0 207196.0 186369.0 266205.0 271127.0 255479.0 252611.0 260581.0 220526.0 201175.0 True False 277214.1307368078 227765.04956933952 190812.74376836803 251290.39689825437 218001.61065145498 242081.23149492458 228681.8573347374 253741.02485839213 223750.7755557961 237646.43499957595 1.1664981666453464 0.95841980364547 0.8029270195814573 1.0574128616686498 0.9173359181754356 1.0186613213674194 0.9622776682307288 1.0677249370849804 0.9415280122177947 1.0 17.858457233968878 QSMAFSILNT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 QSMAFSILNTPK 12 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 QSMAFS(0.021)ILNT(0.978)PK;QSMAFSILNT(1)PK;QSMAFS(0.004)ILNT(0.996)PK 98.654 0.0098909 48638400.0 214378.0 157999.0 150303.0 154850.0 138438.0 138958.0 112093.0 131008.0 144300.0 119085.0 True False 211320.93040788986 157633.1630229294 137945.6675263582 166238.1855644568 130295.34901958013 133015.09026691914 117896.62706473876 137095.10994821752 128047.41445363539 139668.68357921156 1.513015838572299 1.1286221004118613 0.9876635476994656 1.1902323506197912 0.9328887885284932 0.9523615950133953 0.8441164049339305 0.981573724581327 0.9167940240591922 1.0 17.09164905130651 -1.5228787468801521 0.7125050458110639 0.9469746589581894 75.71901927540105 0.8063511261866667 0.08047126527973061 130.21106846164233 0.6567656603690777 0.0319276741556171 15542.64549752004 0.029999999889488725 1.5228787468801521 74.77204461644287 QSMDMS(ph)PIK ddPTM_PC-9_Lapatinib_30min_R1 2 QSMDMSPIK 9 0 F5H658;Q14562 F5H658 DHX8 ATP-dependent RNA helicase DHX8 1 QSMDMS(1)PIK;QS(0.005)MDMS(0.995)PIK 112.02 0.0021958000000000004 13548200.0 68653.0 82517.0 83149.0 74779.0 75551.0 84741.0 67649.0 71709.0 80863.0 68774.0 True False 67673.99563058172 82325.9369563292 76312.81018442189 80278.49711543115 71107.23871898105 81116.8249709192 71151.53421090092 75040.86192657487 71755.3574148602 80661.49426440544 0.8389876265960166 1.0206349102146284 0.9460872362997799 0.9952517970009477 0.8815512205352174 1.0056449574938595 0.8821003734157067 0.93031827157322 0.8895862650355665 1.0 16.299592511649294 -7.2842937758772655 24.98853553051859 0.919694426955765 0.9503635761810036 0.02830422146983569 0.06004060425232695 2586.3913118533937 2827896.8952024872 0.023423535692798283 0.015802531635096834 5.196443673268208e-08 7.2842937758772655 0.030669149225238668 QSNAS(ph)SDVEVEEK ddPTM_PC-9_AZD4547_30min_R2 2 QSNASSDVEVEEK 13 0 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 QSNAS(0.72)S(0.28)DVEVEEK;QSNAS(0.771)S(0.229)DVEVEEK 262.73 2.8789e-55 73712000.0 135875.0 191784.0 145481.0 114319.0 132495.0 178479.0 188379.0 185815.0 176140.0 136941.0 True False 179080.42362442933 253774.42745947168 143551.82688440324 87964.52076094357 114100.3562801759 167318.6799155079 205144.36606152143 157101.5613539183 185450.40080306286 132146.7372715966 1.3551634139583149 1.9203987377902334 1.086306252036826 0.6656579086031701 0.8634368024211555 1.2661582371997853 1.5523982679942778 1.1888417723930098 1.4033672312462253 1.0 17.011781279437507 -6.989671008268696 24.93152565859832 1.317230067302417 1.1737424006321573 0.020227167419454184 0.33650199535957137 950.5861681344459 2294460.4874720415 0.1331803196485432 0.11733639921891766 1.0240684625958289e-07 6.989671008268696 -0.1434876666702598 QSNAS(ph)SDVEVEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSNASSDVEVEEK 13 0 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 QSNAS(0.699)S(0.301)DVEVEEK;QSNAS(0.771)S(0.229)DVEVEEK 257.37 6.483199999999999e-44 38712700.0 149368.0 265996.0 137590.0 159100.0 164451.0 129377.0 165549.0 106574.0 102860.0 110599.0 True False 174653.05224752522 292402.3249736779 140870.66741298104 150186.1428091593 132228.00707138123 122592.24236480803 149867.0002490323 103776.54542448714 104364.13290799812 130649.72319879752 1.3368038444426853 2.238063103499703 1.0782316560949101 1.1495328052140992 1.0120802695477753 0.9383276088405547 1.1470900709142233 0.7943112536609054 0.7988086798254975 1.0 16.995344542530297 -5.3851055872248645 6.609656176527142 0.9861618922447749 1.7825511876315168 0.6565013033650247 0.23149412614783918 0.1254478129262875 6.167510959558794 0.05770008943095034 0.1213870489382061 4.1199734065566944e-06 5.3851055872248645 0.7963892953867419 QSNAS(ph)SDVEVEEK ddPTM_PC-9_Lapatinib_30min_R1 1 QSNASSDVEVEEK 13 0 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 QSNAS(0.725)S(0.275)DVEVEEK 163.62 0.00034059 64399000.0 52078.0 61927.0 48935.0 49248.0 56001.0 50861.0 54466.0 68523.0 49918.0 49523.0 True False 51335.35817006446 61783.61183628356 44911.7531945626 52869.86220651195 52707.13128220215 48685.79359278185 57285.98297581522 71706.8287355102 44295.70918015646 58082.984564750375 0.8838278293505437 1.0637127602733252 0.7732342532174014 0.9102469957888116 0.9074452987766964 0.8382109486558387 0.9862782259743098 1.2345582664673866 0.7626279798135375 1.0 15.825827966941938 -7.506812313536519 24.298665554424552 1.0212394782968244 0.9003817650930469 0.12292310796751726 0.12647762301108553 876.2279272422279 1325203.7301951644 0.051780392380233846 0.03375927961785804 3.1130613996728625e-08 7.506812313536519 -0.12085771320377747 QSNAS(ph)SDVEVEEKETSVSK ddPTM_PC-9_Lapatinib_30min_R1 1 QSNASSDVEVEEKETSVSK 19 1 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 QS(0.122)NAS(0.439)S(0.439)DVEVEEKETSVSK 64.028 0.005509600000000001 40196000.0 30633.0 45714.0 46136.0 27755.0 41548.0 42436.0 48292.0 38837.0 37647.0 41262.0 True False 30196.16780259579 45608.152041659814 42342.87617011014 29796.195287965802 39104.22832651087 40621.11120314759 50792.323465429254 40641.50880143903 33406.79841951503 48394.081721841016 0.6239640618899849 0.942432430143129 0.8749598021817641 0.6156991563395717 0.8080374073688129 0.8393817954151745 1.049556508941999 0.839803284935498 0.6903075175913093 1.0 15.562543005714268 -6.8365007618433795 3.778323599638747 0.8880497910493734 0.7785987605482461 0.16123382679749554 0.12961619705383992 0.502853190245858 14.091222676021994 0.04840219061028488 0.0432167455719126 1.457133148611791e-07 6.8365007618433795 -0.10945103050112737 QSNASS(ph)DVEVEEK ddPTM_PC-9_AZD4547_30min_R2 2 QSNASSDVEVEEK 13 0 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 QSNAS(0.096)S(0.904)DVEVEEK;QSNAS(0.085)S(0.915)DVEVEEK 195.6 1.1146999999999999e-06 43542000.0 99521.0 110069.0 104107.0 82908.0 95642.0 129141.0 133200.0 143796.0 125326.0 104164.0 True False 131166.60783460425 145646.65173339064 102726.47315769462 63794.8415158312 82363.75920109112 121065.79285500609 145054.54195740854 121575.6323033553 131950.47650190012 100517.25006505403 1.3049163974314277 1.448971710220178 1.0219785468783795 0.6346656068937784 0.8193992488631144 1.2044280238133573 1.4430810817400028 1.2095001825524718 1.3127147471354692 1.0 16.617083582286348 -6.98330925780209 24.545038651889854 1.2680641367701517 1.0409618311073685 0.13398866020941202 0.23634376773975008 397.5694895912246 584654.2498192138 0.09371818877973613 0.08262946850214015 1.0391799101736772e-07 6.98330925780209 -0.22710230566278322 QSNASS(ph)DVEVEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSNASSDVEVEEK 13 0 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 QSNAS(0.106)S(0.894)DVEVEEK;QSNAS(0.07)S(0.93)DVEVEEK 215.93 1.9427e-14 38980000.0 101095.0 166428.0 109556.0 115839.0 131339.0 90659.0 115868.0 70801.0 85112.0 80360.0 True False 118208.38678273452 182949.87195566524 112168.23053344354 109348.91638510491 105604.06577490024 85904.68244395172 104892.14422832473 68942.54876986027 86356.60198391559 94928.63187059016 1.2452342823594054 1.9272359492662712 1.1816058898473851 1.1519065874052936 1.1124574714071849 0.904939645196402 1.1049579264064098 0.7262566352356686 0.9097002693733094 1.0 16.534555670459454 -5.758199034718467 1.2626516595534756 0.9360584614527101 1.5896397457202267 0.5750439961753561 0.19900241928407245 0.3218679482299985 1.0131324857855541 0.06679430874734935 0.17177469615105928 1.7450222357595653e-06 5.758199034718467 0.6535812842675166 QSNASS(ph)DVEVEEK ddPTM_PC-9_Lapatinib_30min_R1 3 QSNASSDVEVEEK 13 0 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 QSNAS(0.205)S(0.795)DVEVEEK;QSNAS(0.226)S(0.774)DVEVEEK;QSNAS(0.089)S(0.911)DVEVEEK 282.52 1.3952e-82 113965000.0 165243.0 206352.0 170893.0 152898.0 179077.0 178657.0 195596.0 205458.0 167585.0 164967.0 True False 162886.6045181451 205874.20462222915 156842.83720605692 164142.62897277565 168544.0429389282 171016.25657980802 205723.00382142176 215004.32874130545 148709.8125517154 193481.32614528923 0.8418724833208455 1.064052064991708 0.8106355291790811 0.8483641922606912 0.871112713029292 0.8838902440196647 1.0632705900875417 1.1112407229411594 0.7686003373785336 1.0 17.561834805779966 -7.236554302259647 23.967319199030324 0.9950479728031689 0.8888157168080999 0.17363781375790266 0.10509791062703612 774.5630822071112 745998.0071463343 0.039799989093365545 0.03081197564444555 5.8002364439943436e-08 7.236554302259647 -0.10623225599506902 QSNASS(ph)DVEVEEKETSVSK ddPTM_PC-9_AZD4547_30min_R2 1 QSNASSDVEVEEKETSVSK 19 1 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 QS(0.015)NAS(0.157)S(0.828)DVEVEEKETSVSK 80.786 0.0011169 24215000.0 26583.0 25748.0 25730.0 24930.0 26431.0 24998.0 24391.0 31069.0 33252.0 23585.0 True False 35035.84103925087 34070.5374704171 25388.803388316654 19182.77366466047 22761.51188226974 23434.871108241725 26561.75174837201 26267.999944594776 35009.63283469654 22759.29632871529 1.5394079207557188 1.4969943261132583 1.1155355166356233 0.8428544269383963 1.0000973471904602 1.0296834651550306 1.1670726267076712 1.1541657336502347 1.5382563823172803 1.0 14.474168332678724 -5.2562758200313295 5.326044708504992 1.0966225897482595 1.5249160736661658 0.4830682251178452 0.17064490161266432 0.14198046997038472 14.281320543904863 0.047073200391246114 0.11657185760872961 5.54273582501643e-06 5.2562758200313295 0.4282934839179062 QSNASS(ph)DVEVEEKETSVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSNASSDVEVEEKETSVSK 19 1 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 QS(0.144)NAS(0.378)S(0.478)DVEVEEKETSVSK;QS(0.051)NAS(0.195)S(0.754)DVEVEEKETSVSK 59.943000000000005 0.009828100000000001 16380000.0 40570.0 53719.0 40663.0 45277.0 58114.0 41238.0 44588.1 41663.2 37269.0 40273.8 True False 47437.69970597505 59051.867303497 41632.56013528626 42740.27648001452 46726.978874839566 39075.40668464997 40364.39237811094 40569.58514580933 37813.988618979085 47575.12113277462 0.9971114855090741 1.2412341975692 0.8750909959660719 0.8983745172341903 0.9821725675575681 0.82134119166185 0.8484348839692982 0.852747910669235 0.7948269540595858 1.0 15.537919709352598 -5.2804801244580455 24.52491359901369 0.8793584857704794 1.1191728291308611 0.5665936132442563 0.08214552255098222 363.8486465134909 468645.146801785 0.02064720643273028 0.04309344142374382 5.242275918016041e-06 5.2804801244580455 0.23981434336038177 QSNASS(ph)DVEVEEKETSVSK ddPTM_PC-9_Lapatinib_30min_R1 2 QSNASSDVEVEEKETSVSK 19 1 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 QS(0.048)NAS(0.397)S(0.555)DVEVEEKETSVSK;QS(0.025)NAS(0.169)S(0.805)DVEVEEKET(0.001)SVSK 60.333999999999996 0.0094144 40229000.0 42146.6 52357.5 50236.3 39196.4 50085.0 45523.0 40674.7 42547.9 45045.0 38173.7 True False 41545.581755260166 52236.2694255852 46106.06533172587 42079.034011357326 47139.098770898636 43576.087409296066 42780.63694316439 44524.83076274552 39971.55775512136 44771.97318174208 0.9279372518744018 1.1667180540277604 1.0297974838984274 0.9398521222316167 1.0528707005953863 0.9732894110431188 0.9555227054547206 0.9944799748272577 0.8927807937538406 1.0 15.450308281368828 -6.383041316489582 0.7822347910898898 0.9572908279701439 1.0478125460177854 0.14666548467172624 0.06792091410648161 1.1639850580184248 1.5660881785868268 0.0392259049740199 0.05837020437189482 4.13960290944619e-07 6.383041316489582 0.09052171804764153 QSNSGATKRAS(ph)PS(ph)NS(ph)RR ddPTM_PC-9_AZD4547_30min_R2 1 QSNSGATKRASPSNSRR 17 3 Q14686 Q14686 NCOA6 Nuclear receptor coactivator 6 3 QSNS(0.001)GAT(0.001)KRAS(0.998)PS(1)NS(1)RR 61.87 0.04306 0.0 5424.9 4710.3 6360.8 10264.0 7940.6 6930.8 6919.4 6772.1 5904.1 8846.3 True False 7149.905355070233 6232.812360063138 6276.451635927115 7897.793377219214 6838.184754733121 6497.4159803585 7535.213195346046 5725.627552376656 6216.178672540956 8536.59372960416 0.8375595209919604 0.7301287325468343 0.7352407569966614 0.925169174893536 0.801043715014678 0.7611251262697474 0.8826955380592363 0.6707157132851106 0.7281802167747298 1.0 13.059444805361343 -10.67854110091377 4.777587513401158 1.0000193809279467 0.7859321835753809 0.4309147431168858 0.07385999427147989 1.5857318034076838e-05 2.8024417378145824e-06 0.07280349185087961 0.017655808260146056 2.0963263780315523e-11 10.67854110091377 -0.21408719735256587 QSNVAAPGDAT(ph)PPAEK ddPTM_PC-9_Lapatinib_30min_R1 1 QSNVAAPGDATPPAEK 16 0 Q96QC0 Q96QC0 PPP1R10 Serine/threonine-protein phosphatase 1 regulatory subunit 10 1 QS(0.012)NVAAPGDAT(0.988)PPAEK 111.09 0.0022960000000000003 0.0 11902.0 16476.0 20007.0 13292.0 20460.0 19558.0 22219.0 18879.0 18590.0 16127.0 True False 11732.275297440512 16437.850834282413 18362.101689253373 14269.538020812164 19256.583025907676 18721.549931924794 23369.391101598027 19756.18726117793 16496.198438621504 18914.530462123254 0.6202784320200092 0.8690594179538084 0.9707934186377964 0.7544220063716207 1.0180841160434508 0.9897972338998894 1.2355258381060912 1.044497895453451 0.8721442211666576 1.0 14.207207342647065 -6.329838302281736 6.158307053845864 1.039024895627275 0.8205475457555799 0.45588231715075966 0.11839439763270994 0.22874421269333775 16.25205887882748 0.03816310524058511 0.04349570535382212 4.679093221476513e-07 6.329838302281736 -0.2184773498716951 QSPAS(ph)PPPLGGGAPVR ddPTM_PC-9_AZD4547_30min_R2 1 QSPASPPPLGGGAPVR 16 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 QS(0.214)PAS(0.786)PPPLGGGAPVR 102.72 0.001463 38535000.0 29727.0 46269.0 46034.0 64358.0 45082.0 39422.0 50666.0 65334.0 37208.0 36958.0 True False 39179.567639988374 61224.54941039032 45423.55908191876 49521.25742118808 38823.14247196417 36956.93610805285 55175.175846952436 55238.13152596336 39174.73891836251 35664.11166913972 1.098571247293693 1.7166991281986181 1.2736489696790603 1.3885459388587267 1.0885773023629794 1.0362500109607893 1.5470783727580044 1.548843611707315 1.0984358528761717 1.0 15.122185418539415 -8.470762536291408 7.460604851149327 1.000165090970919 1.3378533498004341 0.2345592164106053 0.2118752172192415 0.33742981508803505 41.09801957629671 0.2088416991919946 0.05400728043269647 3.3824973397546843e-09 8.470762536291408 0.33768825882951514 QSPAS(ph)PPPLGGGAPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSPASPPPLGGGAPVR 16 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 QS(0.014)PAS(0.986)PPPLGGGAPVR 108.96 0.00073683 6320300.0 11749.0 9642.4 13150.0 12615.0 20461.0 12663.0 13698.0 13279.0 12423.0 10325.0 True False 13737.873646672442 10599.633747598427 13463.545871652717 11908.22244838182 16451.81393051748 11998.929988062537 12400.426275068101 12930.440320263502 12604.662872993029 12196.840767344967 1.1263468884051793 0.8690474812114627 1.1038551809005448 0.976336633029114 1.348858630225337 0.9837736030946387 1.016691659062091 1.0601466860896165 1.0334366999969318 1.0 13.574219888032967 QSPAS(ph)PPPLGGGAPVR ddPTM_PC-9_Lapatinib_30min_R1 2 QSPASPPPLGGGAPVR 16 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 QS(0.168)PAS(0.832)PPPLGGGAPVR;QS(0.006)PAS(0.994)PPPLGGGAPVR 110.6 0.00055314 53144000.0 57162.0 67023.0 34777.0 28021.0 43494.0 32510.0 37899.0 35252.0 56911.0 28296.0 True False 56346.85939777306 66867.81236138078 31917.769303102166 30081.757815315796 40935.76843249407 31119.62308451146 39861.22477876879 36889.936613753074 50501.08388060188 33186.92589794998 1.697863175728901 2.0148841916542604 0.9617573318254762 0.9064339947549648 1.2334908197996957 0.937707312217001 1.201112296491164 1.1115804075131839 1.521716233552124 1.0 15.018327378438912 -5.2620289864196454 24.999849710043524 1.1075614195011534 1.8563737237836042 0.7193057749492049 0.1866902748500264 24.74449481373653 1049246.416558393 0.04782609316646411 0.11024971930580685 5.469794542442408e-06 5.2620289864196454 0.7488123042824508 QSPCHS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 QSPCHSPR 8 0 H3BRS1;Q12968;I3L3K7;H3BR83;Q12968-5;Q12968-6;Q12968-4;Q12968-3;Q12968-2 H3BRS1 NFATC3 Nuclear factor of activated T-cells, cytoplasmic 3 1 QS(0.002)PCHS(0.998)PR 84.31 0.014072 494380.0 4117.5 2302.1 2067.2 5150.1 3782.7 4020.1 3410.1 3845.7 3868.3 3712.0 True False 5426.779350679586 3046.2088049808626 2039.7875773155147 3962.8240132518204 3257.537399154846 3768.722511490624 3713.592293760951 3251.435430394543 4072.77044070903 3582.0440098448676 1.5149951635894643 0.8504107701102167 0.5694479385818195 1.1063024358049258 0.9094074193956998 1.0521150776296133 1.0367243628371223 0.9077039314587755 1.1369962037081212 1.0 11.806567347389338 -6.778697188269747 24.636808597326137 1.0215654247964074 0.9654362157837696 0.00032711082924208323 0.22868143470298133 1474.1814394988944 2104487.8845207314 0.08174191402371629 0.07227210707381207 1.6645728689021956e-07 6.778697188269747 -0.05612920901263785 QSPDHPT(ph)VGAGVLHITENGPTEVDYSPSDMQDSSLSHK ddPTM_PC-9_AZD4547_30min_R2 2 QSPDHPTVGAGVLHITENGPTEVDYSPSDMQDSSLSHK 38 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QS(0.412)PDHPT(0.463)VGAGVLHIT(0.123)ENGPT(0.001)EVDYSPSDMQDSSLSHK;QS(0.019)PDHPT(0.969)VGAGVLHIT(0.003)ENGPT(0.008)EVDY(0.001)SPSDMQDSSLSHK 79.877 1.4050000000000002e-09 82402000.0 17226.9 13712.8 98740.0 142910.0 123998.0 144051.0 65598.0 182612.0 92184.0 117658.0 True False 22704.69585822033 18145.19443158054 97430.64308443005 109964.30743749009 106783.01806127986 135043.46819798916 71436.09491983548 154393.5114063001 97056.65804263398 113538.82923230811 0.19997296089573893 0.15981488055028512 0.8581261912176351 0.9685171864199488 0.9404977907848124 1.1894033883481492 0.6291776602141317 1.3598300462514066 0.8548322956902216 1.0 16.792826244735856 -5.318090377717834 3.535783427960868 0.9935290693674294 0.16291674439436046 0.7545225536138482 0.18245002773104263 0.09944842390932473 2.4893844447698608 0.045890028472999445 0.11408134521619505 4.807392950451559e-06 5.318090377717834 -0.8306123249730689 down QSPDHPT(ph)VGAGVLHITENGPTEVDYSPSDMQDSSLSHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSPDHPTVGAGVLHITENGPTEVDYSPSDMQDSSLSHK 38 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QS(0.012)PDHPT(0.988)VGAGVLHITENGPTEVDYSPSDMQDSSLSHK;QS(0.326)PDHPT(0.553)VGAGVLHIT(0.04)ENGPT(0.075)EVDY(0.003)S(0.003)PS(0.001)DMQDSSLSHK 100.07 3.9388e-20 55633000.0 13962.5 54454.0 125782.0 115960.0 161349.0 138903.0 118590.0 79994.0 120091.0 73864.0 True False 16326.07547805464 59859.83324605127 128781.11991089134 109463.13714739255 129733.82170348798 131618.6821552437 107356.2966827511 77894.24226064916 121847.10368514876 87254.95849289764 0.18710771009516378 0.6860335994649946 1.4759174966701043 1.2545205342834769 1.4868360944100159 1.5084378518838808 1.2303747378607677 0.8927199508895484 1.3964490475927147 1.0 16.412949498147945 -5.015921906247834 3.1059136118870607 1.2883171657319976 0.20752633651082725 0.7603364347933862 0.19842588201498543 0.12459522669450741 2.317125795791807 0.05385922996977042 0.25055875698068564 9.640023525419932e-06 5.015921906247834 -1.0807908292211703 down QSPDHPT(ph)VGAGVLHITENGPTEVDYSPSDMQDSSLSHK ddPTM_PC-9_Lapatinib_30min_R1 3 QSPDHPTVGAGVLHITENGPTEVDYSPSDMQDSSLSHK 38 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 QS(0.103)PDHPT(0.891)VGAGVLHIT(0.001)ENGPT(0.005)EVDYSPSDMQDSSLSHK;QS(0.372)PDHPT(0.623)VGAGVLHIT(0.002)ENGPT(0.002)EVDYSPSDMQDSSLSHK;QS(0.18)PDHPT(0.786)VGAGVLHIT(0.029)ENGPT(0.005)EVDYSPSDMQDSSLSHK 79.884 1.4024e-09 52302400.0 36605.7 40340.0 94265.0 53736.2 82498.0 111369.0 63553.0 80543.0 106847.0 51478.9 True False 36083.696005336766 40246.59520848222 86514.89557342257 57688.139406708295 77645.62983730847 106606.00748381898 66843.46337278273 84285.32181667745 94812.76571121001 60376.9592736775 0.5976401667029321 0.6665886406443873 1.4329124323943954 0.9554661264940275 1.2860142473448406 1.7656736736375513 1.1071021823042424 1.3959848728821833 1.5703468152717235 1.0 15.881710480699594 -5.039876479878758 1.1594705560242184 1.354356342723063 0.33455801691988796 0.5166938546058326 0.2514337663969158 0.8206315308021217 1.262310314284997 0.07842338522246553 0.9123976666139274 9.122702663475331e-06 5.039876479878758 -1.0197983258031749 QSPGST(ph)SPKPPHTLSR ddPTM_PC-9_Lapatinib_30min_R1 1 QSPGSTSPKPPHTLSR 16 1 E9PPY3;O43159 E9PPY3 RRP8 Ribosomal RNA-processing protein 8 1 QS(0.018)PGS(0.16)T(0.411)S(0.411)PKPPHTLSR 57.413999999999994 0.035958 11457000.0 28882.0 33737.0 61575.0 47764.0 53692.0 63552.0 50074.0 57300.0 51996.0 44659.0 True False 28470.137383689864 33658.88404929512 56512.54118637363 51276.72389603312 50533.94212253345 60834.029106947746 52666.58670603629 59962.36718393427 46139.662937846384 52378.24864562302 0.543548860831737 0.6426118650324102 1.078931477238235 0.9789698056335845 0.9647886943382235 1.1614368689288226 1.0055049198449548 1.1447951914090013 0.88089357950883 1.0 15.676680201121965 -5.193180961092414 4.4005625314736205 1.0326069223410348 0.5699677642742976 0.8205638071023137 0.08141568976980319 0.07855143337962461 2.96700476801402 0.020155558420520844 0.057713896952110016 6.409424541159304e-06 5.193180961092414 -0.46263915806673717 QSPGSTS(ph)PKPPHTLSR ddPTM_PC-9_AZD4547_30min_R2 1 QSPGSTSPKPPHTLSR 16 1 E9PPY3;O43159 E9PPY3 RRP8 Ribosomal RNA-processing protein 8 1 QS(0.001)PGS(0.093)T(0.423)S(0.483)PKPPHTLSR 54.81100000000001 0.0287 11249000.0 36515.0 37982.0 52979.0 50711.0 54841.0 63683.0 43338.0 55790.0 46932.0 48939.0 True False 48126.01044081727 50258.938721507795 52276.463844136364 39020.362427139895 47227.27377456602 59700.891942801725 47194.998043169435 47168.93742666135 49412.72970642306 47225.66050587225 1.0190648457914753 1.0642294503272935 1.1069504012047873 0.8262533971819818 1.0000341608497687 1.2641621377720753 0.9993507245346203 0.9987988928348849 1.0463110346604652 1.0 15.527283354074848 -3.453974730921618 15.210618692311082 1.0343123416715962 1.026782535820965 0.0 0.10368369167291276 0.0 0.0 0.024388564863577513 0.0 0.0003515808963875037 3.453974730921618 -0.007529805850631233 QSPLT(ph)YEDHGAPFAGHLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSPLTYEDHGAPFAGHLPR 19 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 QS(0.054)PLT(0.589)Y(0.357)EDHGAPFAGHLPR 71.697 0.012853 4627300.0 14666.0 14675.0 8346.3 17093.0 16199.0 8590.0 17500.0 14008.0 11361.0 14006.0 True False 17148.66413329628 16131.837016303713 8545.307445519018 16135.33462625369 13024.922235494492 8139.525278169247 15842.273310971812 13640.304842702844 11527.133132099632 16545.17692856501 1.0364751134023449 0.9750174982083344 0.5164832919233198 0.9752288957633488 0.787233783702074 0.49195758457659483 0.9575161014821397 0.8244278620649292 0.6967065497013938 1.0 14.014123098978597 -5.0260557293752655 24.389917001956338 0.7758842197086161 1.0211108928133241 0.22683693830449747 0.1672871660694756 625.9243374056771 585910.6779338347 0.040864681428591905 0.10906381333879046 9.417687394701862e-06 5.0260557293752655 0.24522667310470803 QSPNSS(ph)SAAASVASR ddPTM_PC-9_Lapatinib_30min_R1 1 QSPNSSSAAASVASR 15 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 QS(0.241)PNS(0.081)S(0.438)S(0.241)AAASVASR 93.738 0.0031825 3519600.0 4922.2 7514.8 4513.1 6230.0 6466.5 7356.8 7209.8 5702.0 5719.8 6583.6 True False 4852.008525379072 7497.399942307938 4142.050339069797 6688.17498267076 6086.153183628149 7042.166813538416 7583.088166177669 5966.9357361744005 5075.575891835788 7721.566487904428 0.6283710090406628 0.9709687735063035 0.5364261702024037 0.866168152945074 0.78820187499025 0.9120127145922698 0.9820660325927802 0.7727623333324142 0.6573246374018155 1.0 12.914677843952637 QSPS(ph)SSPTR ddPTM_PC-9_Lapatinib_30min_R1 1 QSPSSSPTR 9 0 P49585;C9JEJ2 P49585 PCYT1A Choline-phosphate cytidylyltransferase A 1 QS(0.01)PS(0.704)S(0.282)S(0.004)PTR 103.31 0.0028964000000000004 4951500.0 3571.5 6584.8 7467.1 7270.5 11796.0 8217.0 14224.0 15009.0 14411.0 11179.0 True False 3520.5697550671143 6569.5533001689055 6853.183861839551 7805.196823677004 11102.182471828297 7865.578064762551 14960.449121433472 15706.372933048344 12787.881425442414 13111.275254918819 0.26851467051203426 0.5010613515801429 0.52269392020189 0.5953041692682648 0.8467660281682522 0.599909460508939 1.1410369190305052 1.1979287008833064 0.9753346777343356 1.0 13.67852039420683 -6.430003853425547 0.6431393110794486 1.1104974103844973 0.34062058330917827 0.7936870788147045 0.13365921483108548 0.37258976875801475 0.3375624142125769 0.09661253023614753 0.14987977880404 3.7153193253907285e-07 6.430003853425547 -0.7698768270753191 down QSPSS(ph)SPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSPSSSPTR 9 0 P49585;C9JEJ2 P49585 PCYT1A Choline-phosphate cytidylyltransferase A 1 QSPS(0.165)S(0.565)S(0.061)PT(0.209)R 119.03 0.0017621 7181200.0 8513.1 11268.0 16416.0 19482.0 36988.0 43569.0 30164.0 26554.0 46248.0 56014.0 True False 9954.199688610697 12386.612572382292 16807.419698026682 18390.486701496204 29740.466920579674 41284.164941159004 27306.647551551614 25856.985636288646 46924.289507379974 66168.89479341995 0.15043623925845856 0.18719690892606622 0.2540078650323485 0.2779325052792783 0.4494629540576392 0.6239210292093987 0.4126810284016875 0.3907725180693202 0.7091593361787006 1.0 16.013865562242003 -8.568926111904865 0.18657844421927702 1.2633009828416157 1.1022324712102834e-13 0.8574042960023049 0.09488971388455704 1.9013191444379993 0.2603027502240989 0.8650745356709761 0.5494429771349723 2.69819844768352e-09 8.568926111904865 -1.2633009828415056 down QSPSSS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 1 QSPSSSPTR 9 0 P49585;C9JEJ2 P49585 PCYT1A Choline-phosphate cytidylyltransferase A 1 QS(0.073)PS(0.031)S(0.247)S(0.617)PT(0.031)R 104.07 0.0027276999999999996 3754900.0 20821.0 14381.0 16169.0 14923.0 19142.0 17606.0 15984.0 15217.0 26510.0 24313.0 True False 27441.644896296224 19029.377014217353 15954.588495363081 11482.73290805167 16484.463714971334 16505.094036791095 17406.545034889015 12865.562301873213 27911.26447876235 23461.809270301248 1.169630380169904 0.8110788385917612 0.6800237914967171 0.48942231077578924 0.702608376236266 0.7034876912789416 0.7419097493441313 0.5483618997005009 1.1896467214953186 1.0 14.518026651425853 -8.268965319196449 24.877755801156052 1.0948233996712087 0.7222699943810745 0.4028619042360616 0.17702350421479673 596.6873115871043 1972382.0976088115 0.16341645228788443 0.04548931227001766 5.3831276803588225e-09 8.268965319196449 -0.37255340529013414 QSPSSS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QSPSSSPTR 9 0 P49585;C9JEJ2 P49585 PCYT1A Choline-phosphate cytidylyltransferase A 1 QS(0.093)PS(0.348)S(0.14)S(0.415)PT(0.003)R;QS(0.275)PS(0.114)S(0.114)S(0.382)PT(0.114)R;QS(0.007)PS(0.061)S(0.21)S(0.722)PTR 119.03 0.0017621 12928200.0 24838.4 39671.0 41656.8 37045.6 94448.0 119867.0 75842.0 78618.0 130463.0 143577.0 True False 29043.050539238113 43609.27470349466 42650.05609629376 34970.05513545568 75941.59240064111 113580.96350620633 68657.69671146983 76554.36080265667 132370.77456325263 169606.37354509323 0.1712379666647164 0.25712049489637995 0.25146493734184105 0.20618361447459518 0.4477519966574282 0.6696739110220322 0.4048061123906751 0.4513648821239796 0.7804587280327601 1.0 17.37183085960401 -8.02251736654608 0.20819338251224329 1.1837366884664098 2.5679399922296574e-19 0.8302785717172384 0.10694007597988524 1.1358571526658106 0.2474200057880666 0.546117505870194 0.516404201720181 9.494730309628655e-09 8.02251736654608 -1.1837366884664098 down QSPSSS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 3 QSPSSSPTR 9 0 P49585;C9JEJ2 P49585 PCYT1A Choline-phosphate cytidylyltransferase A 1 QS(0.026)PS(0.195)S(0.08)S(0.664)PT(0.035)R;QS(0.01)PS(0.158)S(0.073)S(0.522)PT(0.237)R;QS(0.003)PS(0.209)S(0.1)S(0.683)PT(0.005)R 98.75399999999999 0.0043606 21162900.0 37289.3 57347.0 51373.0 64905.0 129856.0 106082.0 181753.0 192834.0 173369.0 167254.0 True False 36757.54774397991 57214.21654488916 47149.31024551474 69678.33021673273 122218.12538671886 101545.12014922003 191163.28101574111 201793.77161512722 153842.3575634952 196163.63104805336 0.18738207254623854 0.291665770251131 0.2403570427077014 0.3552051409553279 0.6230417164167379 0.5176551820879833 0.97450929101589 1.0287012456743048 0.7842552502803596 1.0 17.581698063546213 -6.729929927670274 0.8935389601142925 0.9751917461215257 0.22304339578419896 0.8913821959518919 0.10316681894039866 0.17369978572176986 0.3018465009630315 0.0631436389710867 0.060625754417710544 1.862387604009786e-07 6.729929927670274 -0.7521483503373267 down QSPSSSPT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 QSPSSSPTR 9 0 P49585;C9JEJ2 P49585 PCYT1A Choline-phosphate cytidylyltransferase A 1 QSPS(0.005)S(0.017)S(0.393)PT(0.584)R 87.641 0.026244999999999997 6890700.0 25796.0 17783.0 20369.0 23134.0 23403.0 28886.0 23452.0 24908.0 39978.0 40631.0 True False 33998.5914098678 23531.00698448142 20098.89375113182 17800.81371673709 20153.89741518515 27079.75385361512 25539.182567456042 21059.040928899118 42091.15546329542 39208.52105711388 0.8671225155456148 0.6001503333983066 0.5126154521833243 0.4540037021750241 0.514018301935632 0.6906599158424989 0.651368168930776 0.537103679534942 1.0735206105321466 1.0 15.258879604066337 -8.26325235924923 24.996494456161184 1.0367603656856037 0.5967980641846335 0.7052152382355101 0.11201339437146839 90.05281033640972 1241550.9952883702 0.09570859989302595 0.029595342994957034 5.4544082497303414e-09 8.26325235924923 -0.43996230150097015 QSQQPMKPIS(ph)PVKDPVS(ph)PASQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSQQPMKPISPVKDPVSPASQK 22 2 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 2 QS(0.061)QQPMKPIS(0.944)PVKDPVS(0.794)PAS(0.201)QK 40.756 0.044321 12891000.0 26508.0 25106.0 20764.0 25326.0 30746.0 28947.0 31615.0 25841.0 26314.0 22613.0 True False 30995.280843135 27598.357760226303 21259.09250790852 23907.066327999844 24721.542012007747 27428.968361718864 28620.198327221362 25162.701130802707 26698.792468802887 26712.5578955905 1.1603262017918343 1.0331604284433586 0.7958463802306931 0.8949748062856323 0.9254651729211071 1.026819238686484 1.071413618983518 0.9419802187852766 0.9994846833148133 1.0 14.705230509269942 -6.767117728091159 24.987001494316004 1.0082804471889124 0.952961142821004 0.05306695090181768 0.09333103800085558 440.31152598857454 1937531.9376224827 0.03534134847291231 0.03200484167784028 1.709551828761604e-07 6.767117728091159 -0.05531930436790844 QSQQPMKPIS(ph)PVKDPVS(ph)PASQK ddPTM_PC-9_Lapatinib_30min_R1 1 QSQQPMKPISPVKDPVSPASQK 22 2 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 2 QS(0.02)QQPMKPIS(0.982)PVKDPVS(0.924)PAS(0.074)QK 47.089 0.022371000000000002 13941000.0 40746.0 34499.0 34501.0 36630.0 41733.0 34635.0 35044.0 38323.0 31754.0 26112.0 True False 40164.95456809873 34419.11968511222 31664.46095771133 39323.89239409789 39278.34699023487 33153.74178812839 36858.4068483911 40103.626484989785 28177.53013555606 30625.42440794706 1.311490545668201 1.1238740474786932 1.0339272539026316 1.2840276715934638 1.2825404953422441 1.08255615812871 1.2035231367708534 1.3094880237670505 0.9200698661418129 1.0 14.902442216709488 -8.27250325632413 24.90592030988234 0.9600348905537186 1.1968243593203804 0.5158499746769745 0.09431163897311669 649.745175918331 1462626.060123985 0.08908493177831632 0.023900681249261247 5.339452700570748e-09 8.27250325632413 0.23678946876666185 QSQQPMKPIS(ph)PVKDPVSPASQK ddPTM_PC-9_AZD4547_30min_R2 3 QSQQPMKPISPVKDPVSPASQK 22 2 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 QS(0.012)QQPMKPIS(0.982)PVKDPVS(0.003)PAS(0.004)QK;QS(0.005)QQPMKPIS(0.989)PVKDPVS(0.004)PAS(0.002)QK;QS(0.005)QQPMKPIS(0.992)PVKDPVS(0.002)PAS(0.001)QK 56.708 0.019521 50438000.0 226672.0 187413.0 221610.0 261600.0 248571.0 281480.0 283654.0 260448.0 227962.0 249443.0 True False 298748.9809295067 247990.58718903546 218671.30660259814 201292.1616797103 214061.2072977821 263879.0111028038 308898.65648939053 220201.7460996431 240011.60592635314 240710.07649454018 1.2411153919278612 1.0302459739140186 0.908442678375195 0.8362431877016833 0.8892905956209003 1.0962524500248296 1.283280953534976 0.9148006984437054 0.9970982911128655 1.0 17.876937010949767 -6.783338539067792 24.996143346461523 1.0670236914661777 0.9717191528862908 0.07064766306567893 0.13613484683022573 636.2573364639525 726232.080542591 0.05172315632007526 0.04565254554955328 1.646878124818543e-07 6.783338539067792 -0.09530453857988685 QSQQPMKPIS(ph)PVKDPVSPASQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSQQPMKPISPVKDPVSPASQK 22 2 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 QS(0.004)QQPMKPIS(0.994)PVKDPVS(0.001)PASQK 61.958999999999996 0.014808000000000002 15411000.0 100650.0 102820.0 73859.0 113100.0 114500.0 116470.0 119800.0 115720.0 93910.0 107060.0 True False 117688.05707188534 113027.29008629268 75620.0786718174 106763.37367514717 92064.54694512725 110362.10816628317 108451.67672310988 112682.47261547498 95283.2560897346 126469.13051350659 0.93056745621665 0.8937144552774611 0.5979330953314442 0.844185243004775 0.7279606222586862 0.8726406809169671 0.8575347698111003 0.8909879601286638 0.7534111739588387 1.0 16.948425759041157 -6.807347273327834 24.88325901136441 0.8670155244193709 0.7954951650157577 0.11815332961192215 0.10253828556520257 299.57764338827053 162376.48243151812 0.03626830799150816 0.03198575815075026 1.5583059419503383e-07 6.807347273327834 -0.07152035940361323 QSQQPMKPIS(ph)PVKDPVSPASQK ddPTM_PC-9_Lapatinib_30min_R1 2 QSQQPMKPISPVKDPVSPASQK 22 2 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 QS(0.012)QQPMKPIS(0.987)PVKDPVS(0.001)PAS(0.001)QK;QS(0.003)QQPMKPIS(0.827)PVKDPVS(0.09)PAS(0.08)QK 58.835 0.0029563000000000002 33593000.0 229010.0 173183.0 169738.0 173516.0 169230.0 180275.0 156197.0 171497.0 180895.0 161187.0 True False 225744.2754047098 172782.0054038317 155782.7968476277 186276.9454724075 159276.2241189812 172565.0584915504 164284.11638220947 179465.37670057913 160520.70019120155 189047.95818182337 1.1941111534650508 0.913958590537395 0.8240385050749833 0.9853422764463251 0.8425175582472666 0.9128110144706245 0.8690076209350199 0.949311372768026 0.8491004173492065 1.0 17.528392741974784 -4.762982511843938 5.895760727677637 0.8998985478156697 1.2053592508035933 0.6978639325775069 0.057024666793445 0.06701964532039183 8.635120819512483 0.012850472568932906 0.08297799516856158 1.725907389373516e-05 4.762982511843938 0.3054607029879236 QSS(ph)APASPAASAAGLAGQAAK ddPTM_PC-9_AZD4547_30min_R2 1 QSSAPASPAASAAGLAGQAAK 21 0 Q5SWX3;Q13555-5;Q13555-11;Q13555-6 Q5SWX3;Q13555-6 CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 1 QS(0.003)S(0.997)APASPAASAAGLAGQAAK 333.33 1.3435999999999993e-209 4359900.0 11551.0 12875.0 15623.0 21841.0 27352.0 17004.0 12968.0 19109.0 16921.0 15420.0 True False 15223.977724274422 17036.591965652493 15415.828812113145 16805.894890086223 23554.646929886956 15940.737191957041 14122.126877655202 16156.14313113591 17815.40951509385 14880.150493482715 1.0231064350419237 1.1449206762468072 1.0359995229124228 1.12941699732452 1.582957574266708 1.0712752669362349 0.9490580679167515 1.0857513261181102 1.1972600359718628 1.0 13.861101497064162 -10.687516890378655 6.238143646116354 0.9999991573043351 1.1370181511743407 0.058017983933108974 0.16372884003739974 2.0216899770099755e-06 2.7091685304923534e-07 0.16703167332293445 0.04051088198346215 2.053445163271554e-11 10.687516890378655 0.1370189938700056 QSS(ph)APASPAASAAGLAGQAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSSAPASPAASAAGLAGQAAK 21 0 Q5SWX3;Q13555-5;Q13555-11;Q13555-6 Q5SWX3;Q13555-6 CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 1 QS(0.048)S(0.936)APAS(0.016)PAASAAGLAGQAAK;QS(0.001)S(0.998)APASPAASAAGLAGQAAK 237.73 3.1208999999999994e-51 8439700.0 35014.0 27442.0 29883.0 38223.0 40387.0 31844.0 24036.0 29187.0 27732.0 20397.6 True False 40941.17864197709 30166.260402140113 30595.524051908586 36081.489230637984 32473.457270505332 30174.044581841837 21759.13607442961 28420.872176182736 28137.528036210468 24095.523412687242 1.6991197053814546 1.2519445992302616 1.269759678090198 1.4974353788737231 1.3476966951216665 1.252267654246266 0.9030364562644266 1.1795083962035051 1.167749193669516 1.0 14.556477519771846 -6.939126226721846 3.1527170324005125 1.076388617394078 1.4019061890637108 0.5764198574196083 0.14064943509406067 0.19906637759433796 4.026068319008416 0.05396991045560645 0.04559689104193763 1.1504659599827772e-07 6.939126226721846 0.3255175716696328 QSS(ph)APASPAASAAGLAGQAAK ddPTM_PC-9_Lapatinib_30min_R1 2 QSSAPASPAASAAGLAGQAAK 21 0 Q5SWX3;Q13555-5;Q13555-11;Q13555-6 Q5SWX3;Q13555-6 CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 1 QS(0.001)S(0.999)APASPAASAAGLAGQAAK;QS(0.085)S(0.915)APASPAASAAGLAGQAAK 319.95 0.0 0.0 39851.0 31307.0 44960.0 47144.0 37046.0 25200.0 25860.0 24311.0 37515.0 25136.0 True False 39282.71743222164 31234.510564996363 41263.562350618864 50611.12702777373 34867.0271152383 24122.254744069167 27198.904266048216 25440.57781166888 33289.665649536626 29480.724108385304 1.3324882145974264 1.0594892598351144 1.3996794040375056 1.716753185630818 1.1827059263215638 0.8182382038983904 0.9225995998623364 0.8629563411718483 1.1292010849919365 1.0 14.847484340032189 -6.545808026663119 6.811147441792502 0.9415599778700424 1.3676772870910021 0.5961756485477585 0.16724384908256892 0.12428251661310721 22.10682652405902 0.058578674180559315 0.05955845153749602 2.845718736591095e-07 6.545808026663119 0.4261173092209597 QSS(ph)FEIPDDVPLPAGWEMAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSSFEIPDDVPLPAGWEMAK 20 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 QS(0.163)S(0.837)FEIPDDVPLPAGWEMAK 130.14 2.3831e-05 5299700.0 28587.0 25202.0 24072.0 28918.0 28397.0 24811.0 25630.0 29142.0 22357.0 15246.0 True False 33426.21448101327 27703.8880057844 24645.967773568387 27297.818213420953 22832.811699570142 23509.86748273074 23202.14085486899 28377.053378501325 22683.92882971141 18009.979112730398 1.8559829676529644 1.5382520897096343 1.3684617632980665 1.515705156710894 1.2677866840739818 1.3053800526682862 1.288293601543852 1.5756294441476024 1.259519996537765 1.0 14.136508887613308 -1.5228787456877773 0.6571670259907171 1.3163892587583217 51.09489257286541 0.5876350713667132 0.14227004537660254 165.3912227185811 1.0387959726643146 0.056902012603314914 11996.590193302482 0.029999999971855065 1.5228787456877773 49.77850331410709 QSS(ph)FEIPDDVPLPAGWEMAK ddPTM_PC-9_Lapatinib_30min_R1 1 QSSFEIPDDVPLPAGWEMAK 20 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 QS(0.182)S(0.818)FEIPDDVPLPAGWEMAK 107.95 7.3893e-05 3269400.0 20269.0 13817.0 17474.0 13646.0 14851.0 13458.0 11577.0 11762.0 15111.0 12371.0 True False 19979.96034312062 13785.007585413952 16037.355171590612 14649.572361721543 13977.493378189396 12882.432712130263 12176.400413303956 12308.50545929206 13409.04005411563 14509.310866678661 1.377044059963287 0.9500801045673295 1.105314740234919 1.0096669990967662 0.963346468114443 0.8878735062266394 0.839212869941856 0.8483177162851436 0.9241679482455741 1.0 13.824691378427898 -1.5228787452807264 0.5934590363205365 0.9018473379593233 25.792568840586483 0.7105602645800051 0.0804233316153087 91.64400442111184 0.7264622703214311 0.03714498605622748 2952.016588866321 0.02999999999997314 1.5228787452807264 24.89072150262716 QSS(ph)FEPEFVISPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSSFEPEFVISPR 13 0 A0A0A0MSU3;Q9H9A7 A0A0A0MSU3 RMI1 RecQ-mediated genome instability protein 1 1 QS(0.214)S(0.786)FEPEFVISPR 140.03 7.1024e-05 2368800.0 6943.1 7327.8 7859.7 7605.9 9821.9 6407.7 10244.0 11184.0 8083.6 8200.8 True False 8118.429697524162 8055.255556256924 8047.105056078237 7179.766081660503 7897.3692020990975 6071.668931888833 9273.61415986258 10890.43185042751 8201.807357331276 9687.540122502918 0.838027981805834 0.8315068071352391 0.8306654686658629 0.7411340743748585 0.8152089284001537 0.6267503262035655 0.9572723356594064 1.1241689544211981 0.8466346723333331 1.0 13.24191466510186 -7.461625072527264 10.087230579134228 0.99934456549553 0.7853398590378554 0.5698378423200033 0.0859433581568481 0.4143438659070143 66.9636605326851 0.034849053279626174 0.023432618937718783 3.454418314109991e-08 7.461625072527264 -0.21400470645767455 QSS(ph)FEPEFVISPR ddPTM_PC-9_Lapatinib_30min_R1 1 QSSFEPEFVISPR 13 0 A0A0A0MSU3;Q9H9A7 A0A0A0MSU3 RMI1 RecQ-mediated genome instability protein 1 1 QS(0.081)S(0.918)FEPEFVISPR 89.13600000000001 0.0062563 2093900.0 7458.0 9300.3 12044.0 8249.5 12142.0 14624.0 11480.0 14879.0 12893.0 10230.0 True False 7351.647552370299 9278.765726758731 11053.788811184462 8856.19574952527 11427.831432090468 13998.565610209032 12074.37822792859 15570.33265846001 11440.854570691075 11998.241869381834 0.6127270672156458 0.773343780511468 0.921284045739442 0.7381244557275751 0.9524588315937362 1.1667180710810472 1.0063456262488795 1.2977178513290144 0.953544252169716 1.0 13.550535399370684 -6.479264356220128 3.3764880004647684 1.0980483133838173 0.774389209494185 0.6315952179124843 0.11574397176695453 0.1570475137223466 3.626447814140386 0.03762507703743715 0.041177985540348086 3.3169249397705766e-07 6.479264356220128 -0.32365910388963226 QSS(ph)GASSSSFSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSSGASSSSFSSSR 14 0 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDT5;A0A2R8Y7T2;A0A0J9YVQ7;A0A087WVZ1 A0A2R8Y5G6 DDX3X ATP-dependent RNA helicase DDX3X 1 QS(0.013)S(0.969)GAS(0.004)S(0.009)S(0.004)SFSSSR;QS(0.02)S(0.911)GAS(0.012)S(0.035)S(0.02)S(0.001)FSSSR 125.33 0.00074945 2924000.0 19521.9 19947.8 19448.0 21142.0 27017.0 19708.0 16509.5 23501.0 14894.3 11301.0 True False 22826.572094899537 21928.085753582494 19911.71407695071 19957.482283288817 21723.21279315726 18674.477786048825 14945.6006415708 22884.123651367747 15112.100960252757 13349.781841333215 1.7098835296487431 1.642580082147064 1.4915385370044494 1.4949669230921083 1.6272335421915636 1.3988601467800348 1.1195389422242583 1.714194578110226 1.1320110800210308 1.0 13.704528545507346 -8.29023792504122 0.062478221271777275 1.4363347751295297e-08 2.634941825938613 0.566759426678725 0.16417806476383054 22.519257533189357 1.1875058866073414 25.490931751668043 23.117707987154947 5.125804935989484e-09 8.29023792504122 2.634941811575265 QSS(ph)LTFQSSDPEQMR ddPTM_PC-9_AZD4547_30min_R2 2 QSSLTFQSSDPEQMR 15 0 A0A0X1KG75;A0A590PXD8;A0A0D9SG04;Q53SF7;Q53SF7-3;Q53SF7-2 A0A0X1KG75 COBLL1 Cordon-bleu protein-like 1 1 QS(0.01)S(0.678)LT(0.312)FQSSDPEQMR;QS(0.101)S(0.881)LT(0.017)FQSSDPEQMR 138.98 6.5949e-06 10876100.0 28041.0 25098.0 39025.0 50436.0 41505.0 37648.0 36840.0 59356.0 45044.0 37444.0 True False 36957.45471096692 33210.43768185988 38507.50300151798 38808.75942843226 35742.747178449754 35293.864608492084 40118.688631463454 50183.89406518933 47424.93388085144 36133.09695706658 1.0228144782297472 0.9191140665667434 1.0657127742820571 1.0740501838119472 0.9891968911748518 0.9767738605530638 1.11030307419075 1.3888622424149786 1.3125067562628756 1.0 15.141033292585025 -7.550374090710218 6.000092689563722 1.2628237033652425 1.011029025060675 0.48819607602692006 0.10235947476675648 0.12689259086970855 14.171737368544717 0.04658193481154897 0.02710882639818959 2.8159562899894766e-08 7.550374090710218 -0.2517946783045675 QSS(ph)LTFQSSDPEQMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSSLTFQSSDPEQMR 15 0 A0A0X1KG75;A0A590PXD8;A0A0D9SG04;Q53SF7;Q53SF7-3;Q53SF7-2 A0A0X1KG75 COBLL1 Cordon-bleu protein-like 1 1 QS(0.018)S(0.881)LT(0.062)FQS(0.019)S(0.019)DPEQMR 91.59200000000001 0.0033964 5066800.0 12491.0 15662.0 11444.0 15102.0 17787.0 15694.0 14487.0 14649.0 14800.0 13603.0 True False 14605.479591504416 17216.81985344794 11716.868361611678 14255.883901344609 14301.76503504786 14870.979012291986 13114.68648320278 14264.47927189849 15016.422001150828 16069.116218711253 0.9089161714131767 1.0714229469197738 0.729154497493041 0.8871604204806687 0.89001565738846 0.9254385126031929 0.8161423630710776 0.887695320498622 0.9344896008447158 1.0 13.97200296432199 -8.56321698170739 2.9185713269686713 0.9996561387151408 0.889163518871126 0.15168309760138254 0.08117913055466702 0.5427954549551766 11.75184358122007 0.0779050715972594 0.020812583001522757 2.7339024758358774e-09 8.56321698170739 -0.11049261984401482 QSS(ph)LTFQSSDPEQMR ddPTM_PC-9_Lapatinib_30min_R1 1 QSSLTFQSSDPEQMR 15 0 A0A0X1KG75;A0A590PXD8;A0A0D9SG04;Q53SF7;Q53SF7-3;Q53SF7-2 A0A0X1KG75 COBLL1 Cordon-bleu protein-like 1 1 QS(0.037)S(0.96)LT(0.003)FQSSDPEQMR 131.61 7.9507e-06 2968900.0 12022.0 11961.0 14822.0 10156.0 14990.0 15963.0 14733.0 12912.0 15419.0 12250.0 True False 11850.564075435204 11933.305039381643 13603.392374574581 10902.906119422832 14108.317671473897 15280.299701570473 15495.802650877362 13511.938657573473 13682.349850731847 14367.396177901017 0.824823365952904 0.8305823053544432 0.9468237811593463 0.7588644444978113 0.9819676089376851 1.0635399422668963 1.078539385912667 0.9404584164218043 0.952319382114425 1.0 13.810511003515288 -6.405739996132275 6.423830066795384 1.0092351701810043 0.8478171579052891 0.6487204777779484 0.058677443230825056 0.16159905448280606 7.957506378816334 0.018948935090065604 0.02146557779192112 3.928800748536694e-07 6.405739996132275 -0.16141801227571517 QSS(ph)PAMPHK ddPTM_PC-9_AZD4547_30min_R2 1 QSSPAMPHK 9 0 Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5 Q9UKE5-6 TNIK TRAF2 and NCK-interacting protein kinase 1 QS(0.394)S(0.606)PAMPHK 61.435 0.045666000000000005 18388000.0 6620.1 5135.6 11193.0 14851.0 15253.0 12261.0 12322.0 14510.0 11254.0 12324.0 True False 8725.154093365867 6795.5822678683435 11044.573506623721 11427.33139566277 13135.384235944928 11494.317731744612 13418.63412912303 12267.812906629437 11848.863464503636 11892.540511133653 0.7336661233314684 0.5714155240006458 0.9286975727586485 0.960882276159971 1.1045061585998164 0.9665149108370722 1.128323600542766 1.0315552757751347 0.9963273577593343 1.0 13.537769319301116 -5.4398538100790566 2.9691982647930333 1.0320296623681282 0.651679697444323 0.8346644103448047 0.0652271879160182 0.08919850007785847 1.5086261327988413 0.017211389909472807 0.04056270816750214 3.6320029276486153e-06 5.4398538100790566 -0.38034996492380524 QSS(ph)PAMPHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSSPAMPHK 9 0 Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5 Q9UKE5-6 TNIK TRAF2 and NCK-interacting protein kinase 1 QS(0.374)S(0.626)PAMPHK 63.473 0.039761000000000005 13244000.0 9885.0 13353.0 15741.0 16866.0 18360.0 14993.0 15739.0 13982.0 16676.0 12479.0 True False 11558.335262350593 14678.59759309733 16116.325138074935 15921.052700309761 14762.48979836279 14206.740686331954 14248.087979507734 13614.987315153572 16919.85495210751 14741.343916290356 0.7840760874982174 0.9957435140548017 1.093273803907737 1.0800272207689106 1.0014344609414523 0.9637344306601773 0.9665392830135701 0.9235920003269125 1.1477823900037858 1.0 13.847580435392555 -4.7677137616459 4.804135207444815 1.0182451026608625 0.7686912018140069 0.5475290441707101 0.06440289255105294 0.1423046193339159 8.060913499910537 0.01664992190862581 0.12012890884457797 1.7072072183581146e-05 4.7677137616459 -0.2495539008468557 QSS(ph)PSGSEQLVR ddPTM_PC-9_AZD4547_30min_R2 3 QSSPSGSEQLVR 12 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 QS(0.225)S(0.764)PS(0.01)GS(0.001)EQLVR;QS(0.012)S(0.988)PSGSEQLVR;QS(0.003)S(0.997)PSGSEQLVR 212.55 4.0705e-09 519595000.0 721809.0 905322.0 1059382.0 1105804.0 1135892.0 1045545.0 985216.0 1183840.0 906630.0 1071155.0 True False 951329.2474401152 1197949.6319633734 1045333.9024920982 850877.9723014919 978193.0027231349 980166.905867131 1072898.315383709 1000904.7299368861 954552.6108781717 1033654.1894842087 0.9203554313602952 1.1589462357436464 1.0112994395289179 0.8231746951328841 0.9463445441180394 0.948254180013755 1.0379663975619187 0.9683168124499505 0.9234738470459753 1.0 19.979322179966744 -5.5306569310524365 24.995166309523913 0.9491518245450393 1.0510188554643967 0.198595378467456 0.0749001963640937 233.92846196854933 751726.4358181262 0.02002344954082103 0.03476561544914525 2.946748485176977e-06 5.5306569310524365 0.10186703091935734 QSS(ph)PSGSEQLVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QSSPSGSEQLVR 12 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 QS(0.035)S(0.965)PSGSEQLVR;QS(0.01)S(0.99)PSGSEQLVR;QS(0.065)S(0.932)PS(0.002)GS(0.001)EQLVR;QS(0.011)S(0.774)PS(0.171)GS(0.043)EQLVR 186.69 8.6004e-05 272420900.0 483146.0 689144.0 700102.0 593875.0 696279.0 501783.0 645589.0 493902.0 418044.0 390022.0 True False 564933.0752315263 757557.6619259706 716795.0868316217 560602.109118728 559848.1282306236 475468.61614151346 584434.1362603985 480937.5958324254 424157.1026384527 460729.90118754713 1.2261697662239675 1.6442554737023574 1.5557815652599447 1.2167695382343469 1.2151330460375933 1.0319899249342765 1.268496216012895 1.0438601761960582 0.9206198719578939 1.0 18.81356170575235 -6.064028676246601 1.8765695293641107 1.0780200962301842 1.4902865190056918 0.6143068119310651 0.13872691257635897 0.22812306011345296 1.6008045920308496 0.04611318925035405 0.07071209455115159 8.629215676079283e-07 6.064028676246601 0.4122664227755075 QSS(ph)PSGSEQLVR ddPTM_PC-9_Lapatinib_30min_R1 5 QSSPSGSEQLVR 12 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 QS(0.011)S(0.986)PS(0.001)GS(0.001)EQLVR;QS(0.215)S(0.739)PS(0.025)GS(0.021)EQLVR;QS(0.084)S(0.915)PSGSEQLVR;QS(0.011)S(0.989)PSGSEQLVR;QS(0.07)S(0.753)PS(0.161)GS(0.016)EQLVR 197.06 1.1232e-05 517565400.0 677188.0 793456.0 763918.0 638658.0 893917.0 816140.0 835489.0 756901.0 859421.0 673994.0 True False 667531.1749389293 791618.8013817895 701111.6108487557 685627.0398206345 841338.5595684415 781235.5947152614 878746.532340926 792069.3836629485 762623.9568756615 790492.9648594467 0.8444492292953162 1.0014242207994133 0.8869296021798455 0.8673411027036049 1.064321375355991 0.9882891176067186 1.111643710196929 1.0019942224328107 0.9647447741818418 1.0 19.592393097542214 -6.261270568305048 24.9999964737724 1.0247453336455492 0.9063418760550949 0.5416788018535055 0.05472285853958903 12.276613529567593 1818092.6894563804 0.016452627799427855 0.019910189486401216 5.479354911640123e-07 6.261270568305048 -0.11840345759045434 QSS(ph)SEQCSDGEGR ddPTM_PC-9_AZD4547_30min_R2 2 QSSSEQCSDGEGR 13 0 O60343-2;A0A3B3IRT3;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 QS(0.1)S(0.702)S(0.198)EQCSDGEGR;QS(0.012)S(0.494)S(0.494)EQCSDGEGR 193.54 1.4255000000000002e-06 3714900.0 6613.4 7189.8 8802.3 13068.0 12401.7 9277.9 7864.4 11383.4 7745.9 10883.6 True False 8716.323632734515 9513.76224579793 8685.575750679345 10055.374498587367 10679.938023924355 8697.751446321941 8564.31636463847 9624.357094508998 8155.332460431737 10502.568476710021 0.829923047115894 0.9058510084361917 0.8269953935496874 0.9574205129807695 1.0168882066903595 0.8281547000250127 0.8154497048631747 0.9163812752900872 0.7765083825462886 1.0 13.358454571771205 -6.52760509046152 0.0058907848922078974 1.7683633657221083 3.3789617246508196e-05 0.05324175926547514 0.07751533935006887 48355.936861362374 95.28123039905664 14025.558312088096 14573.723551138655 2.9675285748119835e-07 6.52760509046152 -1.7683295761048619 QSS(ph)SEQCSDGEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSSSEQCSDGEGR 13 0 O60343-2;A0A3B3IRT3;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 QS(0.064)S(0.917)S(0.019)EQCSDGEGR;QS(0.194)S(0.757)S(0.049)EQCSDGEGR 203.2 1.1020000000000001e-09 3665500.0 5069.46 5627.15 6915.299999999999 3802.33 8263.5 6692.3 6374.599999999999 6553.7 6423.5 4364.01 True False 5927.619451600995 6185.776263461218 7080.186978421295 3589.2977774201827 6644.326495031093 6341.344006879165 5770.751739892618 6381.672319219138 6517.431535431916 5155.170467515845 1.1498396588342839 1.199916918837021 1.373414715000311 0.6962520056392588 1.2888664956665996 1.2300939506923636 1.1194104591217149 1.237916836975968 1.2642514105983602 1.0 12.33180441905926 -7.743782376061077 24.628462239377175 1.1883131693871534 1.15238181570607 0.0 0.18127861135691675 1748.212829238952 2438461.6562684006 0.0849723017880159 0.04891618732423162 1.8039214551957915e-08 7.743782376061077 -0.03593135368108347 QSS(ph)TDSSGGHPGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSSTDSSGGHPGPR 14 0 Q9GZV5;C9JR84;C9J038;C9JQS8 Q9GZV5 WWTR1 WW domain-containing transcription regulator protein 1 1 QS(0.005)S(0.391)T(0.113)DS(0.112)S(0.378)GGHPGPR 97.223 0.012084000000000001 0.0 2406.2 1063.6 3881.3 2413.5 2643.7 2884.5 2047.4 927.67 2011.6 1908.1 True False 2813.5221353837096 1169.1871789124777 3973.84491191222 2278.2794196725727 2125.6859629592427 2733.2317421279613 1853.4554501076382 903.319645447612 2041.0158444266901 2254.023425488712 1.248222225008016 0.5187111924797221 1.7630007155096983 1.0107611988010292 0.9430629419915442 1.2126013027284084 0.8222875721470271 0.4007587655180453 0.905498949721058 1.0 11.138286793810543 -7.405347356484049 5.183406827163874 0.717315576989111 1.1040859457944472 0.1963443688371873 0.3257668811905478 0.33981886871895284 13.065166436402595 0.1365350533190092 0.09011083362504779 3.932354329209197e-08 7.405347356484049 0.3867703688053362 QSS(ph)TDSSGGHPGPR ddPTM_PC-9_Lapatinib_30min_R1 2 QSSTDSSGGHPGPR 14 0 Q9GZV5;C9JR84;C9J038;C9JQS8 Q9GZV5 WWTR1 WW domain-containing transcription regulator protein 1 1 QS(0.162)S(0.796)T(0.04)DS(0.001)S(0.001)GGHPGPR;QS(0.069)S(0.466)T(0.466)DSSGGHPGPR 142.4 8.4668e-05 2805000.0 15828.1 9993.14 16381.8 13455.86 14783.71 16897.11 11503.05 15030.1 18884.6 11851.79 True False 15602.388391481956 9970.001498306694 15034.951639576693 14445.448831833095 13914.161243692166 16174.459994387247 12098.621644144083 15728.453316077666 16757.617484345985 13900.356109982496 1.1224452285993702 0.7172479193642218 1.081623486522003 1.0392142990825353 1.0009931496431055 1.1636004046523392 0.8703821361422169 1.131514415287701 1.2055531061043505 1.0 13.762834223039583 QSS(ph)TPSAPELGQQPDVNISEWK ddPTM_PC-9_AZD4547_30min_R2 2 QSSTPSAPELGQQPDVNISEWK 22 0 Q93100-4;Q93100-2;I3L213;Q93100-3;Q93100 Q93100-4;Q93100-3 PHKB Phosphorylase b kinase regulatory subunit beta 1 QS(0.315)S(0.494)T(0.184)PS(0.007)APELGQQPDVNISEWK;QS(0.317)S(0.497)T(0.167)PS(0.019)APELGQQPDVNISEWK 118.61 6.5396e-07 8709400.0 49393.0 46439.0 59934.0 78899.0 64521.0 63642.0 57321.0 69492.0 54562.0 59978.0 True False 65098.94656177703 61449.498585859124 59139.23599982011 60710.054527398584 55563.37286352869 59662.45567928316 62422.457954509126 58753.608167297985 57446.03592946934 57878.18847588234 1.1247578453306906 1.0617039026966943 1.0217879577288989 1.0489280353461006 0.9600053893649725 1.0308279725123795 1.0785143695456254 1.015125208899384 0.9925334127105053 1.0 15.820732147345831 -4.650482534004637 1.3781627252758764 1.0191749105194048 1.1957105673004675 0.5459821310762001 0.030187536784193742 1.3996686342684028 1.9186056654653694 0.009110396382718268 0.37558563793426586 2.236235131449452e-05 4.650482534004637 0.17653565678106276 QSS(ph)TPSAPELGQQPDVNISEWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSSTPSAPELGQQPDVNISEWK 22 0 Q93100-4;Q93100-2;I3L213;Q93100-3;Q93100 Q93100-4;Q93100-3 PHKB Phosphorylase b kinase regulatory subunit beta 1 QS(0.293)S(0.452)T(0.155)PS(0.099)APELGQQPDVNISEWK 131.79 5.5594000000000005e-06 1979300.0 29878.0 33532.0 26924.0 30776.0 37828.0 32750.0 30988.0 29612.0 29571.0 26162.0 True False 34935.75528260099 36860.83535473225 27565.97026983859 29051.720497138234 30415.874950570127 31032.53234691999 28052.592306308245 28834.716376507484 30003.41993216425 30904.963501721944 1.130425385574536 1.1927157057693485 0.89195932130134 0.9400341306185186 0.9841744336269944 1.0041277785424643 0.9077050780126379 0.9330124714400937 0.9708285185482435 1.0 14.915550940794182 -5.25655910383176 24.999449566019678 0.9523063947673237 1.1615705647953807 0.8270615922582045 0.03796411465870421 148.19216305954663 759115.1863448748 0.00986303315576262 0.024378742826314744 5.539121560162271e-06 5.25655910383176 0.20926417002805697 QSS(ph)TPSAPELGQQPDVNISEWK ddPTM_PC-9_Lapatinib_30min_R1 2 QSSTPSAPELGQQPDVNISEWK 22 0 Q93100-4;Q93100-2;I3L213;Q93100-3;Q93100 Q93100-4;Q93100-3 PHKB Phosphorylase b kinase regulatory subunit beta 1 QS(0.346)S(0.502)T(0.141)PS(0.012)APELGQQPDVNISEWK;QS(0.313)S(0.412)T(0.188)PS(0.087)APELGQQPDVNISEWK 114.24 9.8397e-07 6865500.0 54508.0 49563.0 56012.0 41597.0 44680.0 53413.0 41303.0 45308.0 57564.0 37838.6 True False 53730.70592445705 49448.23991864166 51406.909572572615 44656.18214352419 42052.0102442598 51128.65050178437 43441.46724286887 47413.17508498594 51080.536144207035 44378.95159323475 1.2107249945185254 1.1142273114486934 1.1583624156729566 1.0062468927348815 0.9475665542912538 1.1520923470751516 0.9788754732432934 1.0683707790026689 1.1510081764075268 1.0 15.437587965310897 -5.749885363426269 24.947292998660576 1.0441410772963813 1.1564171964542298 0.3899660545421806 0.06735346057373064 233.72985953196476 504661.8923470582 0.018241594751978476 0.03125850503131876 1.7787488674566642e-06 5.749885363426269 0.11227611915784852 QSS(ph)VSSTASVNLGDPGSTR ddPTM_PC-9_AZD4547_30min_R2 1 QSSVSSTASVNLGDPGSTR 19 0 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 QS(0.006)S(0.992)VS(0.001)STASVNLGDPGSTR 216.35 8.866e-28 2642000.0 1901.0 6548.6 6224.4 7517.4 8731.2 7044.3 7272.4 10838.0 7996.2 4738.6 True False 2505.4784567436304 8665.306885147334 6141.86038904929 5784.379572672231 7519.023591482484 6603.818807416081 7919.62951149443 9163.236132463815 8418.86280743416 4572.70305631759 0.5479206556572905 1.8950075652026983 1.3431574964317377 1.2649803631313001 1.6443279825691488 1.4441827352625327 1.7319361029911546 2.0038992297573315 1.8411129486754585 1.0 12.15883152064766 -4.751048006961702 24.99638275726706 1.5918217818196712 0.5479184876164402 0.515922161451417 0.29782115111455065 362.02552773537406 870792.0173045709 0.07487106233777362 1.0302672906192267 1.773993372621139e-05 4.751048006961702 -1.043903294203231 QSS(ph)VSSTASVNLGDPGSTR ddPTM_PC-9_Lapatinib_30min_R1 2 QSSVSSTASVNLGDPGSTR 19 0 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 QS(0.072)S(0.927)VS(0.001)STASVNLGDPGSTR;QS(0.021)S(0.489)VS(0.489)S(0.001)TASVNLGDPGSTR 190.79 2.0202000000000002e-47 4173700.0 13866.0 16255.099999999999 14685.8 7531.200000000001 12668.2 8544.1 7319.9 7878.4 15225.0 5009.8 True False 13668.268297287032 16217.462314660368 13478.390212827377 8085.06957134672 11923.081382639479 8178.688760269897 7698.888605454231 8244.459225513221 13510.200173642423 5875.737254861106 2.3262218347117245 2.7600727553369344 2.293906216054242 1.376009379020104 2.0292060154281564 1.3919425606554339 1.3102846964582697 1.4031361287798272 2.2993199980930368 1.0 12.520554169054577 -5.64177308228301 4.574117821459725 1.5665556402619403 2.5397628379794477 0.5726008154000619 0.36542867591618367 0.14586469473472155 5.130414478398742 0.09785507420181977 0.1744254977667336 2.2815338560206635e-06 5.64177308228301 0.9732071977175074 QSSFEPEFVIS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 QSSFEPEFVISPR 13 0 A0A0A0MSU3;Q9H9A7 A0A0A0MSU3 RMI1 RecQ-mediated genome instability protein 1 1 QSSFEPEFVIS(1)PR;QSSFEPEFVIS(1)PR 138.81 6.5688e-05 6250000.0 12584.6 12242.0 16600.800000000003 15417.300000000001 14507.5 15444.7 14247.7 20662.5 15861.2 11807.3 True False 16586.241024058858 16198.987094642169 16380.662545229974 11863.079679910552 12493.384042678237 14478.940467455837 15515.717698547825 17469.58540201454 16699.59065071842 11393.930020862414 1.45570852143986 1.4217207815899906 1.4376657145723026 1.0411754028846167 1.0964947142735395 1.2707591183151674 1.3617529395158978 1.533236150303498 1.4656567681336714 1.0 13.475977830166354 QSSFEPEFVIS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 QSSFEPEFVISPR 13 0 A0A0A0MSU3;Q9H9A7 A0A0A0MSU3 RMI1 RecQ-mediated genome instability protein 1 1 QSSFEPEFVIS(1)PR;QSSFEPEFVIS(1)PR 140.93 7.494e-05 5438000.0 19986.1 22778.0 19396.0 17735.7 24954.0 24815.1 28794.0 23343.0 27537.0 18198.6 True False 19701.094548998128 22725.25894047614 17801.335750725168 19040.042542560805 23486.254781451607 23753.816019823436 30284.81242987595 24427.60099781113 24435.493082534726 21344.203761889774 0.9230184816814095 1.0647039914907601 0.8340126410575961 0.8920474502102034 1.1003575042413378 1.1128930497860052 1.418877591674312 1.1444606353237117 1.144830388386962 1.0 14.38155672390126 -6.506035352252044 2.5806113097893815 1.1897424837284998 0.9324153294296322 0.48543564426789254 0.11321340042641503 0.23441529435950684 3.1317648184523024 0.03984887577616399 0.04310339112471087 3.1186357119225607e-07 6.506035352252044 -0.25732715429886754 QSSFEPEFVIS(ph)PRPK ddPTM_PC-9_AZD4547_30min_R2 1 QSSFEPEFVISPRPK 15 1 A0A0A0MSU3;Q9H9A7 A0A0A0MSU3 RMI1 RecQ-mediated genome instability protein 1 1 QSSFEPEFVIS(1)PRPK 72.801 0.0089178 19568000.0 9125.8 12091.0 21053.0 18295.0 16395.0 18160.0 11931.0 21758.0 15220.0 11615.0 True False 12027.614571568136 15999.179297608096 20773.823464214158 14077.370404932342 14118.837248299817 17024.45232921313 12992.835886590394 18395.80104910017 16024.498127754165 11208.362385330847 1.0730929424007114 1.4274323712576709 1.8534218247085128 1.2559703122515349 1.2596699466799992 1.5189063079807448 1.1592091190408877 1.6412568060054888 1.4296912944862066 1.0 13.452287885957935 QSSFEPEFVIS(ph)PRPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSSFEPEFVISPRPK 15 1 A0A0A0MSU3;Q9H9A7 A0A0A0MSU3 RMI1 RecQ-mediated genome instability protein 1 1 QSSFEPEFVIS(1)PRPK 111.4 0.00095979 0.0 27049.0 25101.0 25635.0 28751.0 32258.0 29338.0 34221.0 23892.0 30451.0 18985.0 True False 31627.861457897936 27592.861393270137 26246.235621278887 27140.174681999648 25937.276465990548 27799.46363340271 30979.33914141519 23264.860315666494 30896.288267367825 22426.83021482268 1.4102689125007943 1.2303504832810945 1.1703051822246298 1.210165432298219 1.1565288637556854 1.2395627633114674 1.381351659805221 1.0373673003637371 1.3776484671002407 1.0 14.452938105345249 -10.980671580056946 3.0016694074155046 0.9944377697246433 1.2372434964373802 0.30560958213236844 0.11052181440571592 70154381.71962221 80481236.11180905 3273553.279322742 0.025939968057241712 1.0455105509731115e-11 10.980671580056946 0.24280572671273692 QSSFEPEFVIS(ph)PRPK ddPTM_PC-9_Lapatinib_30min_R1 2 QSSFEPEFVISPRPK 15 1 A0A0A0MSU3;Q9H9A7 A0A0A0MSU3 RMI1 RecQ-mediated genome instability protein 1 1 QSSFEPEFVIS(1)PRPK;QSSFEPEFVIS(1)PRPK 119.37 4.6395e-05 30624000.0 31974.0 27875.0 32957.0 30381.0 24921.0 30528.0 28140.0 26716.0 31910.0 27927.0 True False 31518.044896686537 27810.457150134895 30247.402677698992 32615.32008804501 23455.195776571116 29222.388604243777 29596.951509922543 27957.322891553034 28315.95977280323 32754.144739611584 0.9622612694438589 0.8490668088335708 0.9234679433140247 0.9957616157383989 0.7160985567791461 0.8921737641619248 0.9036093521968579 0.8535506914867644 0.8645000502351391 1.0 14.999389857709025 -4.7445651411199785 24.396031380493362 0.8837296368898593 0.9622615837949131 0.07339759408446744 0.07661451598527577 2048.152436668734 2960910.149480394 0.01856881053130168 0.504336779536057 1.8006730258868363e-05 4.7445651411199785 0.07853194690505383 QSSGAS(ph)SSSFSSSR ddPTM_PC-9_AZD4547_30min_R2 2 QSSGASSSSFSSSR 14 0 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDT5;A0A2R8Y7T2;A0A0J9YVQ7;A0A087WVZ1 A0A2R8Y5G6 DDX3X ATP-dependent RNA helicase DDX3X 1 QSS(0.001)GAS(0.763)S(0.134)S(0.027)S(0.027)FS(0.043)S(0.003)S(0.002)R;QSSGAS(0.948)S(0.025)S(0.025)S(0.002)FSSSR 194.32 1.4865e-07 13417800.0 6651.200000000001 9238.8 12393.599999999999 15565.400000000001 12494.2 12771.2 7917.4 14094.0 11255.8 12119.2 True False 8766.14324644568 12225.061425419053 12229.252766165622 11977.037513032734 10759.595995590576 11972.61484509068 8622.033261963863 11916.09614790044 11850.758608828874 11694.910496797384 0.749569075269645 1.0453317645113103 1.0456901546629678 1.0241239141002927 0.9200237999715397 1.0237457437890907 0.7372466223084804 1.0189129836576027 1.0133261483338558 1.0 13.513593200083683 -6.289204798742695 24.522367385999583 0.9459835693847601 0.977511939436562 0.0 0.11244638818053265 3551.7656009287757 3136901.921238478 0.0350992640384526 0.039809942897490125 5.138013029466001e-07 6.289204798742695 0.03152837005180187 QSSGAS(ph)SSSFSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSSGASSSSFSSSR 14 0 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDT5;A0A2R8Y7T2;A0A0J9YVQ7;A0A087WVZ1 A0A2R8Y5G6 DDX3X ATP-dependent RNA helicase DDX3X 1 QSSGAS(0.84)S(0.076)S(0.076)S(0.007)FSSSR 154.81 0.00030680000000000003 4280000.0 4914.5 4702.4 4129.5 4644.6 7106.3 6457.5 7002.5 4522.0 4491.6 3287.1 True False 5746.427784200499 5169.223194921061 4227.962941215958 4384.3781199963705 5713.871528001387 6118.857332220945 6339.172506290291 4403.302291455047 4557.281152727637 3883.025209330716 1.4798842331469082 1.331236063700971 1.088832215422237 1.1291139984002496 1.4714999826092394 1.575796447964756 1.632534471076205 1.1339875622939897 1.1736419175895942 1.0 11.922965358186703 -7.960400074118136 24.905542730978524 1.1091518823156459 1.3746320866433446 0.3707677349960944 0.16951671147573005 186.66897243227774 117401.30593282467 0.10561269392261552 0.0507345838742538 1.0954685803776798e-08 7.960400074118136 0.2654802043276987 QSSGAS(ph)SSSFSSSR ddPTM_PC-9_Lapatinib_30min_R1 2 QSSGASSSSFSSSR 14 0 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDT5;A0A2R8Y7T2;A0A0J9YVQ7;A0A087WVZ1 A0A2R8Y5G6 DDX3X ATP-dependent RNA helicase DDX3X 1 QSSGAS(0.747)S(0.122)S(0.122)S(0.009)FSSSR;QS(0.004)S(0.07)GAS(0.436)S(0.239)S(0.239)S(0.012)FSSSR 141.1 0.00012891 13071600.0 9821.0 7882.200000000001 11019.7 11113.5 10275.0 9396.2 9620.7 7715.6 10739.7 5481.3 True False 9680.95073904917 7863.949250180928 10113.70280327213 11930.823863549202 9670.644701427236 8994.346429612013 10118.812771553365 8074.09494318261 9530.081891945314 6428.735401626849 1.5058872599732942 1.223249793138303 1.573202530736102 1.8558585970936057 1.504284139456104 1.3990848693719629 1.5739973944164367 1.2559382893779372 1.482419371239582 1.0 12.65031925717146 -9.209617097945795 0.5789667433954577 0.979741935798528 1.5216906462593693 0.4503396960637127 0.16494486924594054 2.441605884011327 1.2374532427038676 0.30050949030476404 0.07640560582481162 6.171388715438666e-10 9.209617097945795 0.5419487104608414 QSSGASSSS(ph)FSSSR ddPTM_PC-9_AZD4547_30min_R2 5 QSSGASSSSFSSSR 14 0 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDT5;A0A2R8Y7T2;A0A0J9YVQ7;A0A087WVZ1 A0A2R8Y5G6 DDX3X ATP-dependent RNA helicase DDX3X 1 QSSGAS(0.148)S(0.257)S(0.137)S(0.456)FS(0.001)S(0.001)SR;QSSGAS(0.066)S(0.149)S(0.149)S(0.634)FS(0.002)SSR;QSS(0.001)GAS(0.034)S(0.121)S(0.121)S(0.438)FS(0.261)S(0.021)S(0.003)R;QSSGAS(0.042)S(0.021)S(0.021)S(0.831)FS(0.085)S(0.001)SR;QSSGAS(0.08)S(0.125)S(0.054)S(0.741)FSSSR 178.85 6.8017e-05 49542600.0 54647.4 59057.7 94399.79999999999 97365.2 112268.4 91145.5 78435.0 115591.6 88379.09999999999 94520.8 True False 72024.13646346756 78146.94658873124 93147.9969722665 74919.15741734463 96681.87055364599 85446.15747644799 85415.56305127128 97729.57425071987 93050.6387964913 91211.65556189243 0.7896374210047638 0.8567649178969674 1.0212291005841918 0.8213770154243896 1.0599727628892965 0.936789897629561 0.936454475308935 1.0714592740223277 1.0201617131414857 1.0 16.476930571778375 -3.065622925224386 0.40000807591020493 1.0131420759775822 4.809848901741197e-13 0.48964374511564623 0.06801158054445024 18.526569684323942 0.7804924901565884 0.04970155173995024 11.962109487195178 0.0008597596810883413 3.065622925224386 -1.0131420759771013 QSSGASSSS(ph)FSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QSSGASSSSFSSSR 14 0 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDT5;A0A2R8Y7T2;A0A0J9YVQ7;A0A087WVZ1 A0A2R8Y5G6 DDX3X ATP-dependent RNA helicase DDX3X 1 QSSGAS(0.062)S(0.072)S(0.025)S(0.841)FSSSR;QSSGAS(0.143)S(0.192)S(0.024)S(0.641)FSSSR;QSS(0.001)GAS(0.07)S(0.036)S(0.036)S(0.856)FSSSR;QSSGAS(0.02)S(0.068)S(0.12)S(0.786)FS(0.006)S(0.001)SR 207.66 6.769499999999999e-11 36357800.0 76686.0 67389.0 66648.0 65104.0 96233.0 70237.0 57700.0 79894.0 61362.0 45737.399999999994 True False 89667.42518245996 74078.93456161428 68237.14108394738 61456.433950015846 77376.83446437074 66553.64807482802 52234.23828817561 77796.86715469009 62259.30316450119 54029.2285629408 1.6596095773975896 1.3710899920645134 1.2629671549808492 1.137466434088038 1.4321291738272994 1.2318082239004582 0.9667774217306447 1.4399033490559914 1.15232633928824 1.0 15.721452462655549 -1.5228809759493485 0.8307292072663518 1.2042315460492818 143.97273459811046 0.4839035983850706 0.14629972978482375 528.4711510585421 1.6030180939966376 0.04996221592538358 142375.80864357276 0.029999845911239366 1.5228809759493485 142.7685030520612 QSSGASSSS(ph)FSSSR ddPTM_PC-9_Lapatinib_30min_R1 3 QSSGASSSSFSSSR 14 0 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDT5;A0A2R8Y7T2;A0A0J9YVQ7;A0A087WVZ1 A0A2R8Y5G6 DDX3X ATP-dependent RNA helicase DDX3X 1 QSSGAS(0.096)S(0.322)S(0.135)S(0.447)FSSSR;QSSGAS(0.106)S(0.358)S(0.059)S(0.477)FSSSR;QSSGAS(0.013)S(0.023)S(0.037)S(0.88)FS(0.047)SSR 163.9 0.0001901 30606700.0 66650.0 54574.0 68414.0 63673.0 44357.0 39299.1 37955.9 43999.0 57574.0 46759.8 True False 65699.55877788678 54447.63725601659 62789.265005676985 68355.72482690137 41748.008469217355 37618.369103676516 39921.07078235497 46043.35416624652 51089.40983890235 54842.169126483 1.1979752045613528 0.9928060491269683 1.1449084893207913 1.2464081183450626 0.7612391911948913 0.6859387530226407 0.7279265466375816 0.8395611424496414 0.9315716473773015 1.0 15.742998013506345 -6.268755470930309 24.998225395260334 0.8046069033047104 1.1345720110247277 0.6820124979162064 0.10681517221835397 331.3348169100182 1132129.9191276936 0.03386717206646881 0.03919209474004985 5.385729401123253e-07 6.268755470930309 0.3299651077200173 QSSGASSSSFSSSR ddPTM_PC-9_Lapatinib_30min_R1 3 QSSGASSSSFSSSR 14 0 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDT5;A0A2R8Y7T2;A0A0J9YVQ7;A0A087WVZ1 A0A2R8Y5G6 DDX3X ATP-dependent RNA helicase DDX3X 0 ;; 171.99 0.00022469 4356700.0 2233.7 2745.45 3969.0 1338.87 1657.4099999999999 4413.2 2433.82 3048.92 2310.65 2944.9500000000003 False True 2201.847028389588 2739.0930792049453 3642.68414078306 1437.3349661393893 1559.9244023934323 4224.4577236716705 2559.831290827281 3190.5839538296846 2050.4002647768043 3453.980683600788 0.6374809908010702 0.7930250137790089 1.0546336168231107 0.4161386810770934 0.45163089932720907 1.2230692961686334 0.741124958509799 0.9237411109385502 0.5936339697879417 1.0 11.754044299274357 -6.740010513106633 24.99536195791162 0.8818486915372993 0.6845848569051814 0.19660580147524542 0.2263321698123367 486.93037945061087 567970.9685614893 0.07700903154244793 0.076939847736881 1.8196568090574025e-07 6.740010513106633 -0.19726383463211783 QSSGPSS(ph)SPAAAAAPEKPGPK ddPTM_PC-9_AZD4547_30min_R2 2 QSSGPSSSPAAAAAPEKPGPK 21 1 Q9UDT6-2;Q9UDT6 Q9UDT6-2 CLIP2 CAP-Gly domain-containing linker protein 2 1 QS(0.002)S(0.005)GPS(0.036)S(0.478)S(0.478)PAAAAAPEKPGPK;QS(0.008)S(0.006)GPS(0.125)S(0.43)S(0.43)PAAAAAPEKPGPK 104.95 4.1843e-05 22121600.0 43025.0 39911.0 46177.0 67062.0 48607.0 51982.0 46814.0 54426.0 42051.0 51878.0 True False 56706.055024405396 52811.45024785685 45564.66280848417 51601.89199757157 41858.757067893195 48731.557322530694 50980.355309265215 46015.71228505953 44273.730011182015 50061.767010434254 1.1327218036987445 1.0549258126835492 0.9101688879457099 1.0307644951249186 0.8361422212517723 0.9734286309225499 1.0183490985973287 0.9191787472357615 0.8843820874711463 1.0 15.611421593711933 -5.037216810916279 3.128950143512405 0.9462866842670464 1.1286245712533234 0.5195380678324146 0.05868626954583237 0.1994485093478256 3.74232205678631 0.015078881891549342 0.06559844939439888 9.178742557741816e-06 5.037216810916279 0.18233788698627695 QSSGPSS(ph)SPAAAAAPEKPGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSSGPSSSPAAAAAPEKPGPK 21 1 Q9UDT6-2;Q9UDT6 Q9UDT6-2 CLIP2 CAP-Gly domain-containing linker protein 2 1 QS(0.012)S(0.008)GPS(0.114)S(0.433)S(0.433)PAAAAAPEKPGPK 121.58 7.785200000000001e-07 7456600.0 19870.0 18100.0 17633.0 17248.0 21077.0 17660.0 18282.0 13147.0 20480.0 13919.0 True False 23233.59854961116 19896.848381267275 18053.437593524894 16281.65047877048 16947.11315251049 16733.87851134679 16550.196609782084 12801.90518039794 20779.481255646544 16442.404517256633 1.4130292516053253 1.2100935943027757 1.0979803820406833 0.9902232037706262 1.0306955491043999 1.0177269689347594 1.0065557377822885 0.778590817843101 1.2637738740606985 1.0 14.00513367196682 -4.710776836967313 1.0550849032775185 1.0001394580881486 1.669706475227608 0.5652656101106088 0.11011866986341215 1.3966542498491148 1.1483527043923898 0.033539524264492374 1.0933572496485726 1.9463599654171207e-05 4.710776836967313 0.6695670171394594 QSSGPSS(ph)SPAAAAAPEKPGPK ddPTM_PC-9_Lapatinib_30min_R1 1 QSSGPSSSPAAAAAPEKPGPK 21 1 Q9UDT6-2;Q9UDT6 Q9UDT6-2 CLIP2 CAP-Gly domain-containing linker protein 2 1 QSS(0.001)GPS(0.027)S(0.486)S(0.486)PAAAAAPEKPGPK 112.58 6.9508000000000004e-06 9248900.0 31740.0 21701.0 29146.0 23788.0 24211.0 26794.0 23624.0 21694.0 25341.0 15610.0 True False 31287.38177959686 21650.752667805453 26749.728386813553 25537.448874441736 22786.956580657417 25648.083079864642 24847.13512688025 22701.98243784068 22486.829727439905 18308.16770098246 1.7089302594665388 1.1825734295979615 1.4610816780631795 1.3948664493100167 1.2446333763610116 1.400909337229214 1.3571612152944663 1.2399920521059264 1.2282403184581496 1.0 14.160199791603265 -12.975699945415332 0.07365098893803765 1.165800175355561e-11 1.806308235805892 0.5350294798832065 0.12320416630621205 166.56947255025378 1.1909543593291037 32.30456839538038 6.046174220653398 1.0575479180045815e-13 12.975699945415332 1.806308235794234 QSSGS(ph)ATNVASTPDNR ddPTM_PC-9_AZD4547_30min_R2 2 QSSGSATNVASTPDNR 16 0 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 QS(0.237)S(0.015)GS(0.739)AT(0.002)NVAS(0.007)T(0.001)PDNR;QSS(0.001)GS(0.963)AT(0.035)NVASTPDNR 210.39 2.0827e-17 6962900.0 5361.799999999999 5318.0 12118.4 15399.3 10510.099999999999 11131.3 11334.8 13565.0 8018.299999999999 10593.900000000001 True False 7066.740867631775 7036.93950084194 11957.702097978108 11849.22930181332 9050.954032531614 10435.258051330951 12343.575241582843 11468.840942689754 8442.130968316116 10223.010785532202 0.6912582815262955 0.6883431553061403 1.169684973325165 1.1590743226626126 0.8853511184142244 1.0207617178785653 1.2074305212561942 1.1218652883474087 0.8257969345257445 1.0 13.31953252745598 -5.250175460387878 24.45609734719842 1.0558706271636904 0.689800622051267 0.5997559315029759 0.11717492991112681 364.4445135292096 791272.5554399164 0.0306504907429009 0.07942993923920012 5.62114178168791e-06 5.250175460387878 -0.3660700051124234 QSSGS(ph)ATNVASTPDNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSSGSATNVASTPDNR 16 0 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 QS(0.173)S(0.32)GS(0.506)AT(0.002)NVASTPDNR;QSS(0.008)GS(0.942)AT(0.011)NVAS(0.031)T(0.007)PDNR 185.59 6.5166e-08 7347300.0 8047.2 8048.9 14698.0 15298.7 15503.9 13378.599999999999 12453.6 11380.5 12159.099999999999 8753.4 True False 9409.432020555148 8847.941598673046 15048.456062475405 14441.563438054618 12466.022090677388 12677.002664320726 11273.904851743919 11081.773933636476 12336.903834742778 10340.322128123722 0.9099747477850106 0.8556736907265506 1.455317917180399 1.396626068232081 1.2055738628076358 1.2259775379571274 1.0902856518445425 1.0717049039987008 1.1930869930240113 1.0 13.335993509632445 -10.602787076845873 14.6578104678103 0.9999994411015484 1.1621712868651535 0.0633868979691512 0.17852461321886834 0.0 0.0 0.1882338171986219 0.045653406507242617 2.4958180609411803e-11 10.602787076845873 0.1621718457636051 QSSGS(ph)ATNVASTPDNR ddPTM_PC-9_Lapatinib_30min_R1 2 QSSGSATNVASTPDNR 16 0 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 QSS(0.004)GS(0.965)AT(0.017)NVAS(0.014)TPDNR;QS(0.29)S(0.124)GS(0.579)AT(0.007)NVASTPDNR 183.39 8.4371e-08 9020800.0 13744.3 12662.4 17552.9 13447.7 12683.9 10173.0 9654.599999999999 8108.900000000001 11731.1 5951.299999999999 True False 13548.303761604076 12633.080990775534 16109.768318153428 14436.688718212134 11937.857939506854 9737.92450442126 10154.467947679394 8485.669096994845 10409.819984040492 6979.974275391212 1.9410248844856557 1.809903660435407 2.307998236462055 2.068301135307979 1.710301137010675 1.395123265533163 1.4548001965394433 1.2157163855047648 1.4913837176652123 1.0 12.769006004072098 -6.599675035936305 2.1537783106721395 1.317638758609588 2.0359966212841627 0.7944574700092057 0.17323480759049942 0.1430019949194136 1.3494243680237068 0.06486943780947776 0.06645914806025056 2.5137666725064795e-07 6.599675035936305 0.7183578626745748 QSSLAEPVS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 3 QSSLAEPVSPSK 12 0 E7EMD6;O43572 E7EMD6 AKAP10 A-kinase anchor protein 10, mitochondrial 1 QSSLAEPVS(0.945)PS(0.055)K;QSSLAEPVS(0.536)PS(0.464)K;QSSLAEPVS(0.988)PS(0.012)K 160.03 0.00016392 71596000.0 354002.0 365745.0 354282.0 342792.0 369851.0 404770.0 412972.0 429720.0 391333.0 384241.0 True False 466567.2723009784 483964.91871670453 349583.98919625377 263766.60048360616 318503.5727429667 379459.6679127525 449725.7079672287 363316.64798323886 412018.06345784606 370788.83954385837 1.258309912657959 1.3052305439184053 0.9428115194252054 0.7113660724203291 0.8589891031639123 1.023384814870806 1.2128890085270039 0.9798478520286324 1.111193270986008 1.0 18.50023829505332 -5.260416993077492 24.985766911876148 0.9752829159268748 1.2817702555901702 0.4712610345826822 0.1277518575177492 82.37696980812143 2013108.5257643168 0.03732439144832496 0.08795990621166527 5.490134788017313e-06 5.260416993077492 0.30648733966329544 QSSLAEPVS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QSSLAEPVSPSK 12 0 E7EMD6;O43572 E7EMD6 AKAP10 A-kinase anchor protein 10, mitochondrial 1 QSSLAEPVS(0.786)PS(0.214)K;QSSLAEPVS(0.903)PS(0.097)K;QSSLAEPVS(0.974)PS(0.026)K;QSSLAEPVS(0.982)PS(0.018)K 160.04 0.00014096 63183300.0 157878.0 175286.0 162748.0 187185.0 207310.0 182094.0 230995.0 159099.0 164947.0 179669.0 True False 184603.62716736316 192687.2356551834 166628.5295452271 176697.63131195816 166689.0936872871 172544.67008183373 209113.48134102434 154922.81982932458 167359.037825934 212241.56744097813 0.86978073802013 0.9078675679718934 0.7850890452529499 0.8325307499488557 0.7853744000154039 0.8129636063388778 0.9852616707571966 0.7299362782571175 0.7885309171233602 1.0 17.6953477097098 QSSLAEPVS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 2 QSSLAEPVSPSK 12 0 E7EMD6;O43572 E7EMD6 AKAP10 A-kinase anchor protein 10, mitochondrial 1 QSSLAEPVS(0.5)PS(0.5)K;QSSLAEPVS(0.975)PS(0.025)K 171.46 0.0011064 43414000.0 144823.0 167064.0 125241.0 144595.0 169956.0 177995.0 171315.0 193318.0 172345.0 143771.0 True False 142757.7974627141 166677.17357238138 114944.16842424078 155228.99865477975 159959.52222635233 170382.56877661066 180184.8524492673 202300.26002205646 152933.69122669293 168621.62578718472 0.8466161845864716 0.9884685478168891 0.68166919805002 0.9205758628533943 0.9486299368755658 1.0104431622053531 1.0685749921346173 1.1997290328428996 0.9069636857831549 1.0 17.363430048766467 -6.547768350164548 1.7380261021856276 1.0569105267926102 0.8535061501659471 0.4208958449571486 0.09891497071206276 0.33163199037789987 2.0361762998856734 0.03793983924648949 0.040669505058400876 2.832902644615991e-07 6.547768350164548 -0.2034043766266631 QSSLAEPVS(ph)PSKK ddPTM_PC-9_AZD4547_30min_R2 1 QSSLAEPVSPSKK 13 1 E7EMD6;O43572 E7EMD6 AKAP10 A-kinase anchor protein 10, mitochondrial 1 QSSLAEPVS(0.987)PS(0.013)KK 140.77 0.00010908 6330900.0 21356.0 19934.0 18352.0 15271.0 17016.0 21035.0 20804.0 22533.0 25963.0 22185.0 True False 28146.76376760493 26377.275669383813 18108.64048901621 11750.506884598073 14653.622117540084 19719.678124724564 22655.515697311777 19051.042606828472 27335.351175484993 21408.30990258845 1.3147587967325596 1.2321045327447624 0.8458696913214394 0.5488759709694474 0.6844829033313057 0.9211226021321881 1.0582580222538973 0.889890079764075 1.276857038218599 1.0 14.385883284969351 -10.147178329292746 15.66833507031256 1.0000003293068278 0.9558018445575314 0.0 0.23991700608988345 0.0 0.0 0.2544413092407087 0.061711081971758175 7.125603796643798e-11 10.147178329292746 -0.04419848474929644 QSSLAEPVS(ph)PSKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSSLAEPVSPSKK 13 1 E7EMD6;O43572 E7EMD6 AKAP10 A-kinase anchor protein 10, mitochondrial 1 QSS(0.001)LAEPVS(0.951)PS(0.048)KK 111.64 0.00079787 5295600.0 18727.0 25334.0 20749.0 24783.0 28230.0 21338.0 31427.0 25117.0 22202.0 24576.0 True False 21897.111224890177 27848.992093426798 21243.73485102071 23394.488857570068 22698.53415075063 20218.99771659782 28450.007048223484 24457.705363661305 22526.662247942622 29031.43425649104 0.7542552335317114 0.9592702808749497 0.7317494087041495 0.8058330377645525 0.7818605842966764 0.696451905819194 0.9799724945336603 0.8424559788393124 0.7759403840995545 1.0 14.825328227559954 -10.798864447606972 5.822762258439185 1.000011129641956 0.8170871063595222 0.2890498822230354 0.08731272395803455 1.2417131239514278e-05 1.544009823817896e-06 0.08321365042371834 0.020181047266173407 1.5890426446553706e-11 10.798864447606972 -0.18292402328243385 QSSLAEPVS(ph)PSKK ddPTM_PC-9_Lapatinib_30min_R1 1 QSSLAEPVSPSKK 13 1 E7EMD6;O43572 E7EMD6 AKAP10 A-kinase anchor protein 10, mitochondrial 1 QSS(0.01)LAEPVS(0.733)PS(0.257)KK 134.85 7.109899999999999e-05 8794800.0 15305.0 24572.0 20576.0 23631.0 28708.0 30704.0 30607.0 34256.0 29494.0 23691.0 True False 15086.747893406742 24515.10504369919 18884.32070565689 25368.90257070509 27019.4518820996 29390.86149451984 32191.680698798846 35847.658817676325 26172.075134411127 27785.95778372679 0.5429630322926098 0.882283966401791 0.6796354062236696 0.9130116286854333 0.9724139110987888 1.0577595245513898 1.1585593323564438 1.2901357979702601 0.9419173288220839 1.0 14.76206835048451 -6.111929253806878 1.0341602489616128 1.1205179122218614 0.6823299038004284 0.6622382720363859 0.11885271617472438 0.315111540742457 0.6963740361799663 0.04924683428903836 0.09009317816422531 7.728064643430585e-07 6.111929253806878 -0.438188008421433 QSSLAEPVSPS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSSLAEPVSPSK 12 0 E7EMD6;O43572 E7EMD6 AKAP10 A-kinase anchor protein 10, mitochondrial 1 QSSLAEPVS(0.208)PS(0.792)K 102.29 0.0024529 9898400.0 26498.0 26392.0 25557.0 31740.0 34864.0 26652.0 34797.0 26025.0 25390.0 26062.0 True False 30983.58804064401 29012.023341348387 26166.37580546224 29961.71070246839 28032.6494733181 25254.322201835475 31500.77625153633 25341.87132576682 25761.28071683915 30786.83429332151 1.0063908404952562 0.9423516255337065 0.8499209615435657 0.973198816643772 0.9105401746161064 0.820296168200503 1.023189846393843 0.823139887794964 0.8367628990820749 1.0 14.91002590707735 -4.898773417486741 3.646023387646433 0.9017969741058657 1.0069365522358895 0.16277299604150897 0.07032588672980555 0.42283247202020546 9.81182486352602 0.017211499303016572 0.09898493069707218 1.2624860339770066e-05 4.898773417486741 0.10513957813002384 QSSLAEPVSPS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 2 QSSLAEPVSPSK 12 0 E7EMD6;O43572 E7EMD6 AKAP10 A-kinase anchor protein 10, mitochondrial 1 QSSLAEPVS(0.347)PS(0.653)K;QSSLAEPVS(0.302)PS(0.698)K 150.39 2.0341e-05 33643000.0 169728.0 180011.0 153111.0 172187.0 212532.0 211011.0 236392.0 217756.0 201752.0 189810.0 True False 167307.64759569662 179594.19558934265 140522.80460555147 184850.20637899355 200031.285613989 201986.55142066572 248631.22108506088 227873.73871736077 179028.5652172548 222618.40559407324 0.7515445416528975 0.8067356115954681 0.6312272528884404 0.8303455677247686 0.8985388475862591 0.9073218850959339 1.1168493477507873 1.023606912057713 0.8041948047355033 1.0 17.76421335086136 -6.354781237002255 1.688988719193531 0.982465943763719 0.7383723418950329 0.5880578273308904 0.0870832652998046 0.2628763750332808 1.4898523507674875 0.032897753112259995 0.04093928232252128 4.417929314335942e-07 6.354781237002255 -0.24409360186868612 QSSLAEPVSPS(ph)KK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSSLAEPVSPSKK 13 1 E7EMD6;O43572 E7EMD6 AKAP10 A-kinase anchor protein 10, mitochondrial 1 QS(0.002)S(0.034)LAEPVS(0.104)PS(0.86)KK;QSSLAEPVS(0.312)PS(0.688)KK 127.66 0.00016799 18880200.0 55665.0 80834.0 51279.0 67357.0 82415.0 57522.0 91904.0 73982.0 70137.0 76574.0 True False 65087.985066135094 88858.66530670506 52501.685836690434 63583.205664340385 66266.37237102778 54505.445058306315 83198.18779266006 72040.0508904085 71162.62093883219 90456.26004054939 0.7195520247792436 0.9823384834490376 0.5804096456470252 0.7029165879269997 0.7325791751872358 0.6025613377545437 0.9197615262378114 0.7964075770777463 0.7867075303238458 1.0 16.464932727801624 -8.958572420467123 0.6222494984790412 1.0032620936499523 0.7373685118455788 0.3013153898846982 0.11591239757272753 2.045098830840228 1.440019427153176 0.14239360850528804 0.048772186537504765 1.100088385544315e-09 8.958572420467123 -0.2658935818043735 QSSLAEPVSPS(ph)KK ddPTM_PC-9_Lapatinib_30min_R1 1 QSSLAEPVSPSKK 13 1 E7EMD6;O43572 E7EMD6 AKAP10 A-kinase anchor protein 10, mitochondrial 1 QSSLAEPVS(0.023)PS(0.977)KK 60.949 0.025389 17705000.0 50601.0 52512.0 45313.0 50017.0 50234.0 54557.0 55948.0 55915.0 47567.0 47326.0 True False 49879.42046091309 52390.41169032769 41587.54005323826 53695.417031820776 47279.33488384393 52223.724288578655 58844.71368433356 58513.01502774318 42209.50355728401 55506.23604206887 0.8986273258217122 0.9438653280438677 0.7492408604632919 0.9673762960818375 0.851784200391652 0.9408622888606181 1.0601459922401226 1.0541701113257875 0.7604461510467563 1.0 15.760362244734091 -6.9641713731123 6.823978532457028 0.9770283721949439 0.883818103274776 0.1561042193846529 0.09500147124944369 0.3357653737699729 45.9023391068802 0.03336202875883753 0.02912884074921422 1.0859970033634149e-07 6.9641713731123 -0.09321026892016793 QSSPS(ph)PSRDR ddPTM_PC-9_AZD4547_30min_R2 1 QSSPSPSRDR 10 1 Q15464 Q15464 SHB SH2 domain-containing adapter protein B 1 QS(0.001)S(0.224)PS(0.551)PS(0.224)RDR 93.348 0.033066000000000005 1544400.0 9666.5 9099.4 11186.0 16758.0 12783.0 11428.0 12493.0 12873.0 8236.2 9347.9 True False 12740.245924309475 12040.603101534625 11037.666331197435 12894.702008519067 11008.301100641453 10713.405353427726 13604.85279785214 10883.773642111699 8671.548717464453 9020.632866279318 1.4123450220366147 1.3347847407186337 1.2236022122636356 1.4294675550671936 1.2203468718688664 1.1876556237507774 1.5081927176871843 1.2065421355077117 0.961301590033688 1.0 13.139012937767339 -8.121538257394565 3.9687459411246833 0.9841760085868048 1.3229703196763476 0.6662932828625836 0.09762339759881403 0.13995583339560191 3.660669679918998 0.0728092260139533 0.02509010461224117 7.558954698888544e-09 8.121538257394565 0.33879431108954283 QSSPSPS(ph)RDR ddPTM_PC-9_AZD4547_30min_R2 1 QSSPSPSRDR 10 1 Q15464 Q15464 SHB SH2 domain-containing adapter protein B 1 QSSPS(0.016)PS(0.984)RDR 89.43 0.0044135 2856900.0 9636.5 6555.6 11904.0 13244.0 11689.0 9212.6 9268.5 9139.3 7962.0 7700.3 True False 12700.70654834823 8674.56949825487 11746.14518206457 10190.800417760265 10066.184116826871 8636.53466564476 10093.378544536352 7727.031185221119 8382.855065254838 7430.714840788911 1.7092173257182628 1.1673936739757733 1.5807557460807493 1.3714428067970805 1.3546723743954296 1.1622750772559358 1.358332106775443 1.0398772326459977 1.1281357507139704 1.0 12.859285290534139 -6.980930089598702 0.3659330991905594 0.9777328668031804 1.558905302136322 0.5654835746311647 0.14440320397115658 1.162362010259243 0.3475525870645611 0.1584818693259757 0.24960534044460703 1.0448884062267756e-07 6.980930089598702 0.5811724353331416 QSSPSPS(ph)RDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSSPSPSRDR 10 1 Q15464 Q15464 SHB SH2 domain-containing adapter protein B 1 QS(0.003)SPS(0.155)PS(0.842)RDR;QSS(0.203)PS(0.28)PS(0.516)RDR 123.26 0.0022703000000000003 3230300.0 11570.9 11717.2 12498.400000000001 15239.3 17528.8 14527.1 13517.599999999999 12311.7 14026.5 12495.5 True False 13529.624834307784 12880.406179722911 12796.40925644596 14385.491427477216 14094.157471543662 13765.273302502033 12237.115069050997 11988.53092032443 14231.611026969058 14760.835235676434 0.9165893811758798 0.8726068663507205 0.8669163399044979 0.9745716416309543 0.9548346856063108 0.9325538211572092 0.8290259239175238 0.8121851324069089 0.9641467301641401 1.0 13.849486737551809 -6.075931446469948 0.006053216158953255 1.802819183968348 4.13696067202635e-05 0.08362865124682128 0.058297609494964965 44704.45370904041 70.15860144173621 10176.129777488604 10719.480116453045 8.395925060194875e-07 6.075931446469948 -1.8027778143616278 QSSS(ph)EQCSDGEGR ddPTM_PC-9_Lapatinib_30min_R1 1 QSSSEQCSDGEGR 13 0 O60343-2;A0A3B3IRT3;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 QS(0.017)S(0.342)S(0.641)EQCSDGEGR 120.92 0.00020513 2539900.0 774.08 900.5 1051.9 1128.1 2714.0 2378.9 1985.2 2374.1 1275.2 1074.6 True False 763.041477251114 898.4149475765556 965.4168424514229 1211.0642372312818 2554.367855929299 2277.1599924867505 2087.9839423417993 2484.409353078157 1131.5735475486908 1260.343178185505 0.6054235786396306 0.7128335862221182 0.7659952139712594 0.9609003787165579 2.026724070190771 1.8067777347477214 1.6566788938770114 1.9712165671058892 0.8978297079195513 1.0 10.299600902557748 -6.080490435211891 4.937655541627092 1.6234481401659715 0.7177161047973001 0.5533819369577031 0.3540271689047546 0.15201022835218791 6.523618109044766 0.10265932657985545 0.13606725604774347 8.30825016373337e-07 6.080490435211891 -0.9057320353686714 QSSTAT(ph)SPTPSSDR ddPTM_PC-9_AZD4547_30min_R2 2 QSSTATSPTPSSDR 14 0 Q8IVL0-3;Q8IVL0-2;Q8IVL0;F8VZV4;H0YHX7;A0A1B0GTC4 Q8IVL0-3 NAV3 Neuron navigator 3 1 QSSTAT(0.5)S(0.5)PTPSSDR;QSS(0.001)T(0.005)AT(0.497)S(0.497)PTPSSDR 192.4 1.63e-06 5526500.0 15396.3 17665.3 30458.0 36170.0 30222.0 28415.0 24631.0 35464.0 28211.0 28983.0 True False 20292.003137065734 23375.262761230355 30054.10701909634 27831.565320929367 26026.196969693006 26638.205558072204 26823.11128343041 29983.85368164758 29702.175866102014 27968.313991738614 0.7255354449703212 0.835776613782834 1.0745770026743062 0.9951105858276033 0.930560096592906 0.9524423090337407 0.9590535665236568 1.0720651123447886 1.0619937932216992 1.0 14.77150566628912 -5.05367823344956 3.9243020661926478 1.0011458645438343 0.7411490880960748 0.7806909746796868 0.04917122849520044 0.10181468409949414 3.143473394596123 0.014073714926478489 0.04915918660563152 8.837344122122042e-06 5.05367823344956 -0.2599967764477594 QSSTAT(ph)SPTPSSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSSTATSPTPSSDR 14 0 Q8IVL0-3;Q8IVL0-2;Q8IVL0;F8VZV4;H0YHX7;A0A1B0GTC4 Q8IVL0-3 NAV3 Neuron navigator 3 1 QSST(0.003)AT(0.496)S(0.496)PT(0.005)PSSDR 133.23 2.6391e-05 3552800.0 7300.7 8815.0 9558.2 12192.0 12762.0 11448.0 13525.0 11406.0 13749.0 9649.7 True False 8536.564314602214 9690.094943694523 9786.10373767536 11508.92176699731 10261.377712783544 10847.646726947783 12243.814087479632 11106.604585655958 13950.053114447475 11399.114223016837 0.7488796188536626 0.8500743789485414 0.8584968574062954 1.0096329891807516 0.9001907965852293 0.9516218992739328 1.0741022370630513 0.9743392660483873 1.2237839573780074 1.0 13.476634102561396 -4.968851419408649 0.3675473363853861 1.0825560764871591 0.5592791288270964 0.6368441918445367 0.07562107525513795 3.467639159479235 0.41463957609320196 0.06818937326084301 0.7979280595060281 1.0743569078735065e-05 4.968851419408649 -0.5232769476600627 QSSTAT(ph)SPTPSSDR ddPTM_PC-9_Lapatinib_30min_R1 1 QSSTATSPTPSSDR 14 0 Q8IVL0-3;Q8IVL0-2;Q8IVL0;F8VZV4;H0YHX7;A0A1B0GTC4 Q8IVL0-3 NAV3 Neuron navigator 3 1 QSSTAT(0.499)S(0.499)PT(0.002)PSSDR 165.78 0.0011379 3185400.0 10993.0 8080.2 10460.0 9181.0 10010.0 10568.0 8034.5 8113.2 11283.0 7123.5 True False 10836.237804130697 8061.490793346006 9600.019176767646 9856.20136691818 9421.2314804172 10116.031275211233 8450.487096889576 8490.168890692765 10012.189724742679 8354.787483532898 1.2970093883882363 0.9648947755086561 1.149044089474337 1.179707010662394 1.127644658704514 1.2108065339961918 1.0114544641075909 1.0162040515604616 1.198377546344115 1.0 13.028387416317488 -7.268892746408961 24.94956113345195 1.057859355415077 1.1458459050387768 0.20465652675259804 0.0939592107138221 1058.4247825792713 3542978.4628119366 0.03757409309893867 0.025922462477661664 5.3840273031737585e-08 7.268892746408961 0.08798654962369978 QSSTPGSLFLS(ph)PPAPAPK ddPTM_PC-9_AZD4547_30min_R2 2 QSSTPGSLFLSPPAPAPK 18 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;F6UYG0 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 QSSTPGSLFLS(1)PPAPAPK;QSSTPGSLFLS(1)PPAPAPK 171.0 6.1734e-08 11300600.0 68778.0 52460.0 72192.0 85172.0 80747.0 72727.0 59048.0 77139.0 61264.0 63586.0 True False 90647.9733287286 69416.66908878676 71234.68691058517 65536.91129428249 69536.6728446762 68179.36919309913 64303.157608866844 65218.94002787657 64502.28996706516 61359.873494072126 1.4773168223282918 1.1313039798801572 1.1609327538373597 1.0680744200134946 1.1332597165702114 1.1111393376599095 1.0479675714305223 1.062892348273457 1.0512128903475757 1.0 15.90500788798249 -2.0656492067321848 1.0987514983419906 1.0756781372008792 199.99998310461646 0.8831322480533775 0.043217327573012436 241.45363424801022 0.7874721798557391 0.012922506068170952 120436.3485365013 0.008597076539546276 2.0656492067321848 198.9243049674156 QSSTPGSLFLS(ph)PPAPAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSSTPGSLFLSPPAPAPK 18 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;F6UYG0 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 QSSTPGSLFLS(1)PPAPAPK;QSSTPGSLFLS(1)PPAPAPK 167.9 2.6287e-12 3539800.0 83902.0 80893.0 77524.0 75030.0 84580.0 70778.0 79437.0 63019.0 65461.0 51169.0 True False 98104.95145996353 88923.52243678723 79372.4661714074 70826.31235054202 68007.15616261023 67066.27708245194 71912.15228592389 61364.818024149856 66418.24328495497 60445.53464641889 1.6230305850355444 1.471134682767762 1.3131237342130093 1.1717377100698396 1.125098099643318 1.10953236619978 1.1897016497013373 1.015208458045882 1.0988114121824535 1.0 15.883348145303172 -3.9829694576118526 0.4875217621732824 1.0574023402581785 2.699082323606882 0.9422462418875248 0.04578553207959812 2.043386550639821 0.20752249054487376 0.02801238825687659 2.26904987871871 0.0001039993302291848 3.9829694576118526 1.6416799833487035 QSSTPGSLFLS(ph)PPAPAPK ddPTM_PC-9_Lapatinib_30min_R1 2 QSSTPGSLFLSPPAPAPK 18 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;F6UYG0 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 QSSTPGSLFLS(1)PPAPAPK;QS(0.001)S(0.002)T(0.007)PGS(0.4)LFLS(0.591)PPAPAPK 133.78 4.3426999999999996e-05 10969300.0 50954.0 43007.0 58685.0 45979.0 46514.0 51183.0 46122.0 40863.0 52901.0 39863.0 True False 50227.38661618078 42907.419933842226 53860.14583065101 49360.44904144766 43778.13797004252 48994.022403400486 48509.9714833208 42761.64415771566 46942.73230777387 46753.26643589132 1.0743075392401347 0.9177416511138838 1.1520081897273369 1.0557647155869065 0.9363653346033408 1.047927260239276 1.0375739532517647 0.9146236705482595 1.0040524627758864 1.0 15.512779542544132 -7.118076394991184 0.9254570439750724 0.9767463442817107 1.0375291892618839 0.09610619951081334 0.06829266730111788 1.4391530425903984 2.4833588598765663 0.049517147649442816 0.03227857527289455 7.619449675693323e-08 7.118076394991184 0.06078284498017317 QSSVS(ph)STASVNLGDPGSTR ddPTM_PC-9_AZD4547_30min_R2 1 QSSVSSTASVNLGDPGSTR 19 0 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 QSS(0.052)VS(0.91)S(0.036)T(0.002)ASVNLGDPGSTR 197.41 6.0056e-59 0.0 3500.9 6895.6 6377.4 7845.8 8644.5 4592.3 7204.9 9445.2 6540.0 5473.7 True False 4614.113376756326 9124.467849192493 6292.831509080865 6037.072026401648 7444.360389931548 4305.142755035541 7846.122142259257 7985.6613691038165 6885.691048325378 5282.06742906461 0.8735430659910052 1.7274425159711233 1.1913576631859182 1.1429373266199936 1.4093648916651285 0.8150488067127779 1.4854263501230445 1.5118438899819155 1.3035977182791758 1.0 12.366887003235666 QSSVT(ph)QVTEQSPK ddPTM_PC-9_Lapatinib_30min_R1 1 QSSVTQVTEQSPK 13 0 Q14966-3;Q14966;Q14966-2;Q14966-6;Q14966-4;C9JWN0 Q14966-3 ZNF638 Zinc finger protein 638 1 QS(0.001)S(0.002)VT(0.457)QVT(0.171)EQS(0.369)PK 98.0 0.0070163 13082000.0 45421.0 38767.0 31434.0 39903.0 34235.0 33882.0 42427.0 34637.0 34802.0 29972.0 True False 44773.28821080873 38677.23739333739 28849.617858748978 42837.59973250584 32221.364608599655 32432.945842799676 44623.662463094624 36246.361468585186 30882.23227869315 35152.62026482039 1.273682811509115 1.10026612815672 0.8206960858511234 1.2186175428685277 0.9166134520232553 0.9226323841144076 1.2694263507791068 1.0311140733044977 0.8785186437324871 1.0 15.101344610872001 -4.858943530073232 3.9877829234863755 1.0159261208807562 1.2781694580884786 0.262912877030302 0.13507434742567231 0.306446339494374 8.09103422203925 0.033498711283604876 0.1925964600392477 1.3837462913931102e-05 4.858943530073232 0.2622433372077224 QSSVTQVTEQS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 QSSVTQVTEQSPK 13 0 Q14966-3;Q14966;Q14966-2;Q14966-6;Q14966-4;C9JWN0 Q14966-3 ZNF638 Zinc finger protein 638 1 QSSVTQVT(0.002)EQS(0.998)PK;QSSVTQVT(0.075)EQS(0.925)PK 177.67 4.4766000000000005e-05 21887300.0 48294.0 36472.0 36415.0 47695.0 46362.0 45484.0 40349.0 43545.0 38151.0 40644.0 True False 63650.487422397106 48260.86075116718 35932.11330686168 36699.65463040437 39925.43656637243 42639.87828975383 43939.982833629714 36816.120814554044 40167.583973189845 39221.065931070785 1.622864802661404 1.2304831499476179 0.9161432116610678 0.935712830826738 1.0179589875639674 1.0871677573651735 1.1203158759339231 0.9386823111655527 1.024132899492903 1.0 15.259341124477078 -4.859491336722567 2.745008961815961 1.008812195827916 1.6857864794290172 0.898450695114698 0.06366659608504942 0.11408311644420069 1.3262834697625836 0.018072912539984547 0.1638086630629114 1.3820019737097649e-05 4.859491336722567 0.6769742836011012 QSSVTQVTEQS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QSSVTQVTEQSPK 13 0 Q14966-3;Q14966;Q14966-2;Q14966-6;Q14966-4;C9JWN0 Q14966-3 ZNF638 Zinc finger protein 638 1 QSSVTQVTEQS(1)PK;QSSVTQVTEQS(1)PK 209.6 3.7564e-10 11631500.0 49432.0 41746.0 30746.0 47114.0 47073.0 38392.0 42673.0 36508.0 31427.0 31727.0 True False 57799.8612734966 45890.26699029741 31479.101244854326 44474.35532564892 37849.3835663579 36378.65593474663 38630.70451423428 35549.70368342345 31886.560420957238 37478.8539492062 1.5421992719369373 1.2244309031565082 0.8399163242162332 1.18665195541794 1.0098863646592255 0.9706448330583793 1.0307333454376473 0.9485269675428909 0.8507880327443309 1.0 15.193789217629902 -4.915242034177862 3.0344951045713984 0.9880045298965779 1.561304270475518 0.7769121001366555 0.09389324350680567 0.1324232396370456 2.125557993043912 0.02402269926482486 0.1579683627126283 1.2155084038021933e-05 4.915242034177862 0.5732997405789401 QSSVTQVTEQS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 QSSVTQVTEQSPK 13 0 Q14966-3;Q14966;Q14966-2;Q14966-6;Q14966-4;C9JWN0 Q14966-3 ZNF638 Zinc finger protein 638 1 QSSVTQVT(0.001)EQS(0.999)PK 182.7 6.5535e-05 14373000.0 33423.0 29749.0 27187.0 24744.0 23240.0 29549.0 24768.0 23189.0 26384.0 18587.0 True False 32946.38189097248 29680.1180182731 24951.789804854885 26563.756303564267 21873.068891597963 28285.258152083312 26050.365849245245 24266.44559560651 23412.356084163 21799.738184379294 1.5113200723933633 1.3614896549326694 1.1445912604002835 1.2185355658353114 1.0033638343083962 1.2975044889461675 1.1949852621584125 1.1131530750674221 1.0739741865771228 1.0 14.412023187837622 -4.997177225915279 1.6985628148916365 1.1363366755037196 1.5673005238314608 0.6732091406449793 0.0880755693159102 0.36879756981007616 1.4519196917236523 0.024510716378207942 0.22795557880116574 1.0065208462708356e-05 4.997177225915279 0.43096384832774115 QSTLYSFFPKS(ph)PALSDANK ddPTM_PC-9_AZD4547_30min_R2 2 QSTLYSFFPKSPALSDANK 19 1 P52701-2;P52701;P52701-3;A0A087WWJ1;F8WAX8;F8W7G9 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 QSTLYSFFPKS(0.655)PALS(0.345)DANK;QSTLYSFFPKS(0.939)PALS(0.061)DANK 105.65 0.0001115 39616000.0 68425.0 40323.0 98748.0 242490.0 197016.0 96727.0 74512.0 100078.0 78412.0 148515.0 True False 90182.72667158474 53356.621190757716 97438.53699920293 186587.6769331537 169663.72914370438 90678.64539910764 81143.42365112927 84613.24466365707 82556.69823872921 143315.53505444765 0.6292599517374233 0.3723017268887616 0.6798881709661455 1.3019361569020855 1.1838474390040596 0.6327202795192964 0.5661872149470866 0.5903982749079594 0.5760484947243487 1.0 17.12883547713698 -14.522878745280225 0.01753786145906876 1.7696323845662647 1.1763792190995327e-09 0.029018040634554598 0.2822870684261087 33883.35926212918 44.86746291452473 2944.4873681434387 1731.572108029699 3.000000000000774e-15 14.522878745280225 -1.7696323833898855 QSTLYSFFPKS(ph)PALSDANK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSTLYSFFPKSPALSDANK 19 1 P52701-2;P52701;P52701-3;A0A087WWJ1;F8WAX8;F8W7G9 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 QSTLYSFFPKS(0.937)PALS(0.063)DANK 70.699 0.0032268 10849000.0 27470.0 9874.9 14826.0 41454.0 42870.0 55443.0 36205.0 73691.0 45657.0 29579.0 True False 32120.128442768888 10855.214811059453 15179.508067918108 39131.4667756813 34469.931244869986 52535.47147817662 32775.40029849909 71756.68933206837 46324.647250442125 34941.43855276485 0.9192560401960693 0.31066880073260467 0.4344271070864935 1.1199157331942449 0.9865057843230226 1.503529152036575 0.9380094711614452 2.053627220405051 1.3257796235403292 1.0 15.092651385348969 -6.17582849541358 1.2835735961624195 1.4093712334503985 0.5288470854659865 0.47488385182708837 0.34409502360676786 0.3546982372633109 1.187175544732754 0.1305201852751379 0.20300624111474078 6.670701458108465e-07 6.17582849541358 -0.880524147984412 QSTLYSFFPKS(ph)PALSDANK ddPTM_PC-9_Lapatinib_30min_R1 1 QSTLYSFFPKSPALSDANK 19 1 P52701-2;P52701;P52701-3;A0A087WWJ1;F8WAX8;F8W7G9 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 QSTLYSFFPKS(0.831)PALS(0.169)DANK 109.77 7.4685e-05 12826000.0 86553.0 23335.0 52990.0 41055.0 34574.0 37131.0 18596.0 14443.0 48526.0 26458.0 True False 85318.73834812357 23280.969241198123 48633.36674731525 44074.32165546517 32540.425295099318 35542.99368658856 19558.80988907318 15114.074506763756 43060.49087856628 31031.230046931043 2.749447515264111 0.750243197127166 1.5672394124810094 1.4203214499975672 1.04863472204891 1.145394289328332 0.6302943795490159 0.4870601160155597 1.3876501451422456 1.0 14.921433264538404 -4.755238918002842 24.999896889425553 1.050295515127006 2.7494503129618626 0.7005073499179588 0.3336467807918452 123.45203550972376 497703.7549866045 0.08833328184775527 0.7982554188699816 1.7569567951049245e-05 4.755238918002842 1.6991547978348567 QSTLYSFFPKSPALS(ph)DANK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSTLYSFFPKSPALSDANK 19 1 P52701-2;P52701;P52701-3;A0A087WWJ1;F8WAX8;F8W7G9 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 QSTLYSFFPKS(0.303)PALS(0.697)DANK 72.30199999999999 0.0026886999999999996 11364000.0 26744.0 4125.3 14637.0 41616.0 54026.0 53687.0 42413.0 69814.0 42202.0 33357.0 True False 31271.230981922512 4534.832520842092 14986.00159113161 39284.39044089238 43439.99312888605 50871.55920943795 38395.33359647128 67981.45647404756 42819.12441165994 39404.3600461333 0.7935982451005729 0.11508453672468891 0.38031328445853463 0.996955423077536 1.1024159021496092 1.2910134601825596 0.9743930253281444 1.7252267615679373 1.0866595564939705 1.0 15.266067650574227 -5.8838198138608275 2.9288929911239636 1.2207233147828747 0.39035811357913386 0.643645830303812 0.25399981081885714 0.14790979550109914 2.549397445704273 0.07364407706845401 0.11859144191391685 1.3067129229249197e-06 5.8838198138608275 -0.8303652012037408 QSTLYSFFPKSPALS(ph)DANK ddPTM_PC-9_Lapatinib_30min_R1 1 QSTLYSFFPKSPALSDANK 19 1 P52701-2;P52701;P52701-3;A0A087WWJ1;F8WAX8;F8W7G9 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 QSTLY(0.001)S(0.001)FFPKS(0.328)PALS(0.67)DANK 59.251999999999995 0.010558 9304700.0 56835.0 20317.0 39474.0 34213.0 28619.0 26198.0 14854.0 18113.0 26108.0 14062.0 True False 56024.52247773749 20269.95723477276 36228.60009404645 36729.13815122225 26935.686687118843 25077.572610520805 15623.06743881981 18954.596104757453 23167.442110571836 16492.597963562795 3.396949504348122 1.2290336112937033 2.196658171992462 2.2270074267479374 1.6331985261890232 1.5205350100648092 0.9472775285819708 1.1492789763404143 1.4047175685574715 1.0 14.009531053881494 -6.596244764637249 1.3084988586468502 1.1322954545980086 2.2216679882070616 0.49779187288966176 0.5061325768255207 0.38963003518337147 1.3931416419048506 0.21861358971501177 0.22914459832546666 2.533700256338642e-07 6.596244764637249 1.089372533609053 QSVDKVTS(ph)PTKV ddPTM_PC-9_AZD4547_30min_R2 1 QSVDKVTSPTKV 12 2 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4 E7EX44;Q05682-5 CALD1 Caldesmon 1 QSVDKVT(0.002)S(0.997)PT(0.001)KV 149.69 0.0021687 46632000.0 25242.0 15333.0 22791.0 34084.0 32066.0 28753.0 22496.0 21969.0 25311.0 29377.0 True False 33268.43093378365 20289.0923968427 22488.77644862515 26226.46039255064 27614.189399449944 26955.07036464014 24498.10041947343 18574.195847397823 26648.88778656938 28348.520171662884 1.1735508849255103 0.7157019934015333 0.7932963100876383 0.9251438958272874 0.9740963278588709 0.950845765543147 0.8641756349582465 0.6552086576273758 0.9400451108276032 1.0 14.790985806190475 -7.517802111590414 24.909342325238054 0.8305145944318694 0.9092152348254228 0.016282670768793195 0.1408576215178436 698.5841501959252 3427774.3760342835 0.0634113634019082 0.037945145580930255 3.0352739065826444e-08 7.517802111590414 0.0787006403935534 QSVDKVTS(ph)PTKV ddPTM_PC-9_Lapatinib_30min_R1 1 QSVDKVTSPTKV 12 2 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4 E7EX44;Q05682-5 CALD1 Caldesmon 1 QSVDKVT(0.083)S(0.917)PTKV 193.51 0.00023489 42154000.0 120710.0 64886.0 64346.0 63545.0 63041.0 58522.0 56523.0 51691.0 67070.0 51143.0 True False 118988.65326449697 64735.76045358397 59055.72026274293 68218.31127990579 59333.05232337465 56019.150481445045 59449.48437083692 54092.752567273106 59515.87032158926 59982.999406236086 1.9837062908215692 1.0792351348614582 0.9845409673962261 1.1372940992479532 0.9891644784473071 0.9339171271188725 0.9911055625647207 0.9018013954408788 0.9922123086662742 1.0 15.87226604447552 -4.75898853083062 4.2742531419412355 0.9926549738398399 2.081057283770316 0.9638965068826527 0.0572779738524748 0.04053270356698919 1.5068698351448067 0.015562655865022404 0.13884858119387902 1.741852872921145e-05 4.75898853083062 1.0884023099304763 QSVENDIHGLR ddPTM_PC-9_AZD4547_30min_R2 2 QSVENDIHGLR 11 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ; 170.4 8.4905e-05 9120500.0 66455.0 75801.0 84395.0 102293.0 101293.0 85749.0 73330.0 103876.0 88465.0 88784.0 False True 87586.30765013059 100302.19088065434 83275.8671572865 78710.92926109556 87230.21539445176 80387.10147454271 79856.2279409669 87824.35103301461 93141.0792951231 85675.69918374627 1.022300471248991 1.17071925687515 0.9719893499636003 0.9187077550693393 1.0181441905407922 0.9382719048739684 0.9320755908825615 1.025078894829445 1.0871353275491342 1.0 16.386598439912895 -5.283735805181218 24.607272686861943 0.9823745407352659 1.0965098696677296 0.36133917459632414 0.05834296909272305 581.8653954516273 642170.4953934752 0.01542235305008898 0.032140308703118785 5.20312422480904e-06 5.283735805181218 0.1141353289324637 QSVENDIHGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QSVENDIHGLR 11 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ;; 187.58 9.118e-05 7992300.0 68627.0 97620.0 105574.0 87275.0 104462.0 81134.0 83622.0 73202.0 80536.0 63745.0 False True 80244.19565496568 107311.06845189552 108091.28455162466 82385.26469936746 83993.42098674149 76879.19021175594 75700.71878914762 71280.52506393005 81713.68664085715 75301.46389485757 1.065639251940833 1.425086085998707 1.4354473201550382 1.094072551025049 1.1154287930447193 1.0209521334020986 1.0053020867542166 0.9466021160419682 1.085154025092432 1.0 16.200390291369928 -5.902182075614932 5.323192071187163 1.0312248968710174 1.3188912744894397 0.5902012412625703 0.10418532712459723 0.13981408899196512 6.211886127939631 0.030088207581967997 0.04532730124136165 1.2526159123893065e-06 5.902182075614932 0.2876663776184223 QSVENDIHGLR ddPTM_PC-9_Lapatinib_30min_R1 2 QSVENDIHGLR 11 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ; 155.47 0.00054341 12584900.0 81394.0 81981.0 108700.0 100062.0 109230.0 97257.0 92039.0 106449.0 108893.0 93687.0 False True 80233.30663416834 81791.17803139777 99763.10559413426 107420.89327704668 102805.3061544426 93097.54482714018 96804.3290697142 111395.00915118009 96628.32364587473 109880.6731199192 0.7301857947903636 0.744363642022235 0.9079222283727454 0.9776140810478289 0.9356086310305468 0.8472604160837037 0.8809950496395846 1.0137816413775351 0.8793932627298214 1.0 16.745578127820835 -5.273831310714234 4.225232214965501 0.9292939017852245 0.7326393365417755 0.6971576490325215 0.05110519521162773 0.10833469305045414 4.817557773614914 0.013663933712260714 0.03419134818495113 5.323149816654083e-06 5.273831310714234 -0.19665456524344904 QSVENDIHGLRK ddPTM_PC-9_AZD4547_30min_R2 1 QSVENDIHGLRK 12 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 0 79.036 0.0062783000000000005 6023300.0 18072.0 19498.0 29780.0 42229.0 43305.0 32091.0 29498.0 34071.0 27494.0 31375.0 False True 23818.520079048332 25800.34719582853 29385.09774209366 32493.756481546236 37292.8482487114 30084.344696959164 32123.2648548021 28806.109823692066 28947.276709886555 30276.570799806756 0.7866980787401576 0.8521555286569378 0.9705556793862935 1.0732310702027599 1.2317395023134334 0.9936509948858271 1.0609941616970417 0.9514323803102538 0.956094958748476 1.0 14.885914190874624 -5.2872852037787545 2.3536255011008484 1.042457465302048 0.7977945901182708 0.5650646947784143 0.07628857644235157 0.24378746535420617 2.5491137242326647 0.022995222598960575 0.07624622409191172 5.160773468908555e-06 5.2872852037787545 -0.24466287518377716 QSVENDIHGLRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QSVENDIHGLRK 12 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 0 49.934 0.043735 4808600.0 30975.0 27791.0 46632.0 46104.0 53673.0 38618.0 38785.0 42915.0 34479.0 32513.0 False True 36218.45571586336 30549.906815679497 47743.88373284482 43520.94235118471 43156.16094485433 36592.80409689638 35111.00402091667 41788.52672220108 34983.190147140485 38407.34952723359 0.9430084648299372 0.7954182517597941 1.2430923851954676 1.1331409974105402 1.1236432994225098 0.9527552551094273 0.9141740956641755 1.0880346401557854 0.9108462462981172 1.0 15.229094787160859 -6.791738600201624 24.993490425786554 0.9749774465969543 1.049253515792947 0.0857744656242232 0.12148109849142794 622.8450740214168 513773.7704246572 0.04622691916660124 0.04077265187050952 1.6153305241024516e-07 6.791738600201624 0.07427606919599272 QSVENDIHGLRK ddPTM_PC-9_Lapatinib_30min_R1 2 QSVENDIHGLRK 12 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ; 97.163 0.0016098 14881500.0 69854.0 62595.0 77856.0 70359.0 66828.0 65752.0 59033.0 51729.0 78400.0 53680.0 False True 68857.86915034542 62450.0651233253 71454.98021285103 75533.43557074359 62897.3084289032 62939.94023539821 62089.43988931259 54132.51818599887 69569.7664114001 62958.51647589612 1.0937022186141867 0.9919240258342892 1.1349533663203106 1.1997334085796292 0.999027803537646 0.9997049447550909 0.9861960440742555 0.859812479964068 1.1050096207085045 1.0 15.94211392582554 -6.458152086680868 12.339388516788437 0.9831548813511094 1.0992144305783258 0.36344491970137627 0.07317912397778077 1.498621215013725 284.12593564484513 0.023005497072711045 0.026076381583877768 3.482153512690291e-07 6.458152086680868 0.1160595492272164 QSYVDTS(ph)PAAPVSYADMR ddPTM_PC-9_AZD4547_30min_R2 1 QSYVDTSPAAPVSYADMR 18 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 QSYVDT(0.142)S(0.858)PAAPVSYADMR 122.1 0.0003472 0.0 8608.4 7916.6 13014.0 17689.0 20831.0 25142.0 12087.0 22695.0 17960.0 18488.0 True False 11345.692134156687 10475.486132449289 12841.42585680345 13611.07434232568 17938.975219233507 23569.866765477793 13162.719584378363 19188.009229218136 18909.32893393331 17840.740747309246 0.6359428845950722 0.5871665465476376 0.7197809798755247 0.7629209198826855 1.0055061879613423 1.3211260170927945 0.7377899702042122 1.0755163981692906 1.0598959539718231 1.0 14.122887896729397 -6.101123788766365 2.3969714445961032 1.038396189633201 0.6411396724629642 0.6341226129290591 0.13513761215365494 0.19539157005211596 2.2055046439037445 0.043533872558085225 0.06194329066414468 7.922754727131293e-07 6.101123788766365 -0.3972565171702368 QT(ph)EPVSPVLK ddPTM_PC-9_AZD4547_30min_R2 1 QTEPVSPVLK 10 0 Q8IYH5-4;Q8IYH5-2;Q8IYH5 Q8IYH5-4 ZZZ3 ZZ-type zinc finger-containing protein 3 1 QT(0.644)EPVS(0.356)PVLK 102.97 0.007361499999999999 4568600.0 36966.0 44978.0 42863.0 40241.0 43412.0 53072.0 48922.0 52888.0 45489.0 42626.0 True False 48720.419059434505 59516.25890727131 42294.6086138133 30964.05916725241 37384.993145665845 49753.3994502202 53275.96322552808 44715.374845335486 47893.455672365926 41133.67671434465 1.1844411429052757 1.44689859164756 1.0282233924171384 0.7527666292095458 0.9088658279999678 1.2095539087287466 1.2951908869101658 1.0870745923313434 1.1643368523792554 1.0 15.328032411768977 -5.276217792252358 24.651510109494104 1.0568388493981586 1.3156698692934525 0.30572086307804125 0.15666876277860425 787.2222884473833 1313146.8321255273 0.04596504005478984 0.09637529135909154 5.293978921076383e-06 5.276217792252358 0.2588310198952939 QT(ph)EPVSPVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QTEPVSPVLK 10 0 Q8IYH5-4;Q8IYH5-2;Q8IYH5 Q8IYH5-4 ZZZ3 ZZ-type zinc finger-containing protein 3 1 QT(0.669)EPVS(0.331)PVLK 81.565 0.039391 4283400.0 20453.0 35163.0 30835.0 27420.0 35645.0 22807.0 28212.0 21972.0 22973.0 16930.0 True False 23915.28893483628 38653.75025582877 31570.223342388697 25883.746296839425 28660.618129773513 21610.96077057113 25539.555122807815 21395.258281258346 23308.93666435393 19999.274982193736 1.1958077958390567 1.9327575769743632 1.5785683916290516 1.2942342319851545 1.433082857018135 1.0805872107770083 1.2770240493991327 1.0698016953268314 1.165489083234614 1.0 14.287660079621801 -6.3414275394360535 1.0530933307307986 1.1163958995383834 1.5991619399060486 0.4765279925702376 0.19363451769597015 0.4284492966705787 1.0023541448394968 0.08601086185463434 0.12048225638267127 4.555881931723861e-07 6.3414275394360535 0.48276604036766524 QT(ph)EPVSPVLK ddPTM_PC-9_Lapatinib_30min_R1 2 QTEPVSPVLK 10 0 Q8IYH5-4;Q8IYH5-2;Q8IYH5 Q8IYH5-4 ZZZ3 ZZ-type zinc finger-containing protein 3 1 QT(0.917)EPVS(0.083)PVLK;QT(0.971)EPVS(0.029)PVLK 106.26 0.0057269 11301700.0 53523.0 95901.0 101048.0 99492.0 103086.0 106625.0 112479.0 116419.0 113875.0 99528.0 True False 52759.75220508388 95678.9471266401 92740.22349656 106808.97357558251 97022.68415487382 102064.89730501479 118302.61225602607 121828.25174845432 101049.19834308891 116731.28218727605 0.45197612170865714 0.819651299410376 0.7944761828947756 0.9149987182032762 0.831162669825017 0.8743577162227048 1.0134610880588897 1.043664127264541 0.8656565442412615 1.0 16.83283170736511 -4.413069831025022 0.8248799118332779 0.9436802034007429 8.948785028653666e-39 0.7759392871656083 0.07534655461493983 2.058741476950672 0.7119240437185874 0.028199449296141692 2.043474027844068 3.863048573768269e-05 4.413069831025022 -0.9436802034007429 down QT(ph)PSPDVVLR ddPTM_PC-9_AZD4547_30min_R2 2 QTPSPDVVLR 10 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 QT(0.904)PS(0.096)PDVVLR;QT(0.504)PS(0.496)PDVVLR 102.97 0.007361499999999999 32177000.0 72007.0 69166.0 94090.0 129991.0 119416.0 105030.0 78471.0 111478.0 90595.0 103321.0 True False 94903.72816135656 91522.55688515119 92842.30512268623 100023.5832909298 102837.14967020265 98462.45749654487 85454.76698153015 94251.63660959597 95383.66674664174 99703.76323846493 0.9518570320597832 0.9179448589744154 0.9311815533043831 1.0032077029198982 1.0314269625334351 0.9875500612855386 0.8570866756267267 0.9453167417981112 0.9566706777005932 1.0 16.605360338566193 -4.921081588805 0.0028044725576726335 1.9007743903719623 6.979611310441072e-08 0.03130366312949895 0.04697487453539794 554559.9410289823 254.406736939926 84545.56186723587 87904.42198785758 1.1992739801793283e-05 4.921081588805 -1.9007743205758492 QT(ph)PSPDVVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QTPSPDVVLR 10 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 QT(0.767)PS(0.233)PDVVLR 94.68799999999999 0.015175 17985000.0 31928.0 31286.0 35482.0 34279.0 46968.0 46673.0 42905.0 38351.0 39419.0 29245.0 True False 37332.77979325538 34391.86731802914 36328.02544623432 32358.458764017454 37764.9575626091 44225.385716879304 38840.72779469973 37344.326886243354 39995.428301578686 34546.88699670738 1.080640921331451 0.9955127743147157 1.051557133055048 0.9366533883965146 1.0931508117130333 1.280155451375239 1.1242902377398458 1.0809751654267026 1.1577143927726572 1.0 15.076268095466817 -6.5141227061771065 24.889245705493526 1.1393320737227433 1.0168729123021556 0.3338968321184115 0.07441446589603991 416.1510285969216 1182923.5379802403 0.023437890583140712 0.02462957121036537 3.061098424418047e-07 6.5141227061771065 -0.12245916142058766 QT(ph)PSRQPPLPHR ddPTM_PC-9_Lapatinib_30min_R1 1 QTPSRQPPLPHR 12 1 Q07666;Q07666-3 Q07666 KHDRBS1 KH domain-containing, RNA-binding, signal transduction-associated protein 1 1 QT(0.587)PS(0.413)RQPPLPHR 78.814 0.010020999999999999 2837600.0 26397.0 15319.0 24831.0 18666.0 16315.0 15133.0 9831.8 8004.1 19324.0 9773.7 True False 26020.57393938306 15283.529796696546 22789.49103043188 20038.75990795063 15355.38377652413 14485.796866745979 10340.842496633137 8375.999706403634 17147.52762925885 11463.071022363376 2.2699478951686998 1.333284053364043 1.9880790222769904 1.74811443363274 1.3395523543880359 1.263692499024524 0.9021005345303299 0.7306942171136204 1.495892993754085 1.0 13.484705981689329 -6.506757123242603 1.5785509431416647 1.0235271589192332 1.829780512968353 0.6108991207657041 0.28687585050118086 0.256958861018899 1.301767311445055 0.10996331737189488 0.12252365898306648 3.1134570337371514e-07 6.506757123242603 0.8062533540491199 QT(ph)QSASSTLQK ddPTM_PC-9_AZD4547_30min_R2 1 QTQSASSTLQK 11 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1 C9J840 MAP4K4 1 QT(0.988)QS(0.012)ASSTLQK 126.32 0.0010187999999999998 9447000.0 26358.0 28956.0 37307.0 39941.0 46908.0 40112.0 42432.0 45271.0 31379.0 33907.0 True False 34739.29571954162 38315.46073455793 36812.28480403922 30733.21953229858 40395.63389101846 37603.790298975604 46208.36579832403 38275.4071740883 33037.62987850185 32719.926250487555 1.0617168099217207 1.1710130530623368 1.1250723648403909 0.9392814426603614 1.2345881705774482 1.1492626851020262 1.4122393016590458 1.169788919481992 1.0097097904678058 1.0 14.997881876051123 -4.750016289136541 23.615869787982028 1.145721873517996 1.0617164384293807 0.021916842136952774 0.12764731576921648 1104.9715421228314 2284092.9158700043 0.032652756441647564 0.47286175521426826 1.7782127131452152e-05 4.750016289136541 -0.08400543508861524 QT(ph)QSASSTLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QTQSASSTLQK 11 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1 C9J840 MAP4K4 1 QT(0.714)QS(0.283)AS(0.002)S(0.001)TLQK 131.79 0.00034422 16845000.0 28687.0 33917.0 28827.0 31634.0 33214.0 26108.0 27566.0 20717.0 22479.0 22439.0 True False 33543.14250592324 37284.0556103559 29514.345007006286 29861.649538811747 26705.955128694 24738.85051949274 24954.748919442794 20173.200701475926 22807.71284891011 26507.013072973725 1.2654440699742018 1.4065732531882416 1.1134541989228808 1.1265565628463199 1.0075052611613609 0.9332945379921441 0.941439491908894 0.7610514487595855 0.860440698698135 1.0 14.69408648967954 -5.921395836360325 0.7742514704845448 0.8669110640342171 1.3722349393998883 0.8149883486238527 0.07835846891877866 0.31951740413197605 0.36689739193680837 0.038683837916121615 0.10708054228557849 1.1984065213068759e-06 5.921395836360325 0.5053238753656711 QT(ph)QSASSTLQK ddPTM_PC-9_Lapatinib_30min_R1 1 QTQSASSTLQK 11 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1 C9J840 MAP4K4 1 QT(0.798)QS(0.13)AS(0.064)S(0.007)TLQK 153.32 0.0010084 22564000.0 31538.0 29503.0 23846.0 17462.0 19051.0 15475.0 12385.0 14914.0 18221.0 13352.0 True False 31088.262336639124 29434.687616158913 21885.473928221913 18746.213731524367 17930.45763570709 14813.170323986915 13026.234699729588 15606.95888623378 16168.759104363771 15659.875409578324 1.9852177315295922 1.8796246359760473 1.3975509610271686 1.1970857520397826 1.1449936328829264 0.9459315567048813 0.8318223714450579 0.9966208847796977 1.0324960244877932 1.0 13.934785114100592 -5.36352801022547 0.9533343812099346 0.9601100215339237 2.1856826330912575 0.9647054852834386 0.07062258022202238 0.1696121008977589 0.21945183632751875 0.028037927911159083 0.17811761906714824 4.3298414112361155e-06 5.36352801022547 1.2255726115573338 QT(ph)SLVSSR ddPTM_PC-9_AZD4547_30min_R2 1 QTSLVSSR 8 0 G3V3A4;Q13573;G3V5R3 G3V3A4 SNW1 SNW domain-containing protein 1 1 QT(0.88)S(0.119)LVSSR 87.713 0.028165 6468000.0 26674.0 27601.0 38884.0 63595.0 54721.0 43400.0 35998.0 65241.0 46836.0 41334.0 True False 35155.777146333276 36522.48348302712 38368.372753645715 48934.15528295557 47123.93370321528 40686.191139198774 39201.752262633585 55159.50253903595 49311.65534241094 39886.90924109042 0.8813863449243328 0.9156508783940231 0.9619289507174863 1.2268224390909919 1.1814385872412865 1.020038702253845 0.9828225101545094 1.3828973863488054 1.2362866985845922 1.0 15.28362771567677 -5.635220622023114 5.08733903570827 1.151866522959736 0.907897155571287 0.4460490775894145 0.11717252660218705 0.19877014075935032 8.004630462466682 0.03427317743670593 0.06059633773216623 2.3162177101801135e-06 5.635220622023114 -0.243969367388449 QT(ph)SLVSSR ddPTM_PC-9_Lapatinib_30min_R1 1 QTSLVSSR 8 0 G3V3A4;Q13573;G3V5R3 G3V3A4 SNW1 SNW domain-containing protein 1 1 QT(0.5)S(0.5)LVSSR 92.943 0.018571999999999998 3536400.0 13065.0 15624.0 26830.0 15740.0 21149.0 25789.0 28493.0 23270.0 30200.0 30474.0 True False 12878.69070417243 15587.823587935689 24624.14096679502 16897.572107100765 19905.05740053379 24686.064587095214 29968.22812268028 24351.20915131153 26798.557979901543 35741.390295947414 0.3603298751820714 0.43612807053292313 0.6889530810889318 0.47277321803054534 0.5569189456737712 0.6906856275787984 0.8384740457641982 0.6813167856560024 0.74979058615244 1.0 15.125308134075947 -5.875565502709557 0.15693266317107493 1.105264561685569 3.232767480135952e-16 0.7925599272994001 0.0842035308382171 7.102214357709248 0.3037355754961025 0.47731869540029304 1.7816381234785035 1.331786159767654e-06 5.875565502709557 -1.1052645616855687 down QTAEETGLT(ph)PLETSR ddPTM_PC-9_AZD4547_30min_R2 2 QTAEETGLTPLETSR 15 0 Q5T8C6;Q13042-4;Q13042-3;Q13042-2;Q13042 Q5T8C6 CDC16 Cell division cycle protein 16 homolog 1 QTAEET(0.001)GLT(0.997)PLET(0.002)SR;QTAEET(0.036)GLT(0.955)PLET(0.009)SR 178.99 8.1458e-05 7033800.0 25124.0 19030.5 29952.0 31701.0 26198.2 25219.0 23514.0 35844.0 23034.4 29486.0 True False 33112.90938833612 25181.736963289295 29554.816909710866 24392.824225567667 22561.03214384923 23642.051943305385 25606.70044734612 30305.133413178908 24251.95135834039 28453.7041148399 1.1637468800087167 0.8850073389972406 1.0386983990002443 0.8572811514141563 0.7929031683464588 0.8308954028581108 0.8999425995292846 1.0650681292975632 0.8523302013846378 1.0 14.796328854937519 -4.757856899170651 24.99534031827728 0.9109739914711886 1.1637472373443984 0.4271727366852014 0.08686509246255367 104.98587937530243 732386.9881798819 0.022474900774769335 0.1615435605543793 1.746397499309653e-05 4.757856899170651 0.2527732458732098 QTAEETGLT(ph)PLETSR ddPTM_PC-9_Lapatinib_30min_R1 2 QTAEETGLTPLETSR 15 0 Q5T8C6;Q13042-4;Q13042-3;Q13042-2;Q13042 Q5T8C6 CDC16 Cell division cycle protein 16 homolog 1 QTAEET(0.033)GLT(0.958)PLET(0.005)S(0.005)R;QT(0.061)AEET(0.155)GLT(0.784)PLETSR 147.49 0.00014206 6641800.0 26175.0 24539.0 24962.0 23819.0 27171.0 26145.0 23670.0 21047.0 29608.0 19310.9 True False 25801.73970009287 24482.181453171677 22909.720716106513 25570.7287178547 25572.85520024132 25026.83929697175 24895.516781800525 22024.92045585104 26273.235253937903 22648.76333484317 1.139211855351021 1.080950032071197 1.0115219262705564 1.1290121380939302 1.1291060276522775 1.1049980489870772 1.09919982887105 0.9724557641506014 1.160029572719266 1.0 14.467144658103672 -14.522878620361084 0.2407319192627064 0.49344364269417706 1.097075704041014 0.18857056626684188 0.05575008924114389 301.94370866362146 3.0045659947919154 74.89793498690545 0.08672862465972965 3.0000008629117586e-15 14.522878620361084 0.6036320613468369 QTAEETGLTPLET(ph)SR ddPTM_PC-9_AZD4547_30min_R2 1 QTAEETGLTPLETSR 15 0 Q5T8C6;Q13042-4;Q13042-3;Q13042-2;Q13042 Q5T8C6 CDC16 Cell division cycle protein 16 homolog 1 QTAEET(0.002)GLT(0.023)PLET(0.604)S(0.371)R 82.663 0.026601999999999997 0.0 6449.6 7511.4 9719.3 11021.0 11272.0 12082.0 8563.8 13591.0 9085.0 10813.0 True False 8500.438639986178 9939.313156567157 9590.415731522196 8480.27872275263 9707.077368882918 11326.510630041466 9325.961609721135 11490.823240110318 9565.2145526049 10434.440161221057 0.8146521048227892 0.9525487714718028 0.9191116709034737 0.8127200493486036 0.9302921114022641 1.0854928922910243 0.8937673191495684 1.1012400342104833 0.9166964786624031 1.0 13.349065577239644 -6.5292912229914295 24.966944908242265 1.0001323801878 0.8819856451900856 0.40131339063049487 0.0717448904993666 163.08391475405435 634960.8067417573 0.022135441540742547 0.02219124161894486 2.9560295896946093e-07 6.5292912229914295 -0.11814673499771433 QTAEETGLTPLET(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 1 QTAEETGLTPLETSR 15 0 Q5T8C6;Q13042-4;Q13042-3;Q13042-2;Q13042 Q5T8C6 CDC16 Cell division cycle protein 16 homolog 1 QTAEETGLTPLET(0.65)S(0.349)R 82.007 0.020144 2128400.0 8935.6 10880.0 11128.0 9946.6 10224.0 9610.3 9074.7 6787.2 10548.0 8153.5 True False 8808.176705411648 10854.808028465213 10213.098795322216 10678.106144884909 9622.64442115739 9199.28987170349 9544.543563151889 7102.558089891772 9359.973164635812 9562.82161114416 0.9210855397686101 1.1351051467712647 1.0680005557585899 1.1166271398852654 1.0062557697346897 0.961984887492095 0.9980886344286742 0.742726193032265 0.9787878039812062 1.0 13.223220648034522 -6.914369598572143 1.5362835209554022 0.9055147472770942 1.0645622881090342 0.29849170422322646 0.08797406285428909 0.41085012616142036 1.9912626807065872 0.0407388826100017 0.032576858893907525 1.217952640875208e-07 6.914369598572143 0.15904754083193995 QTAEETGLTPLETS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 QTAEETGLTPLETSR 15 0 Q5T8C6;Q13042-4;Q13042-3;Q13042-2;Q13042 Q5T8C6 CDC16 Cell division cycle protein 16 homolog 1 QTAEETGLT(0.001)PLET(0.238)S(0.761)R 80.488 0.009795 1767800.0 9276.4 8465.3 11599.0 9941.9 9853.0 10545.0 10302.0 9386.2 9963.3 5714.0 True False 9144.116834916586 8445.699117956476 10645.37499343479 10673.060491206166 9273.465911743315 10094.014931595611 10835.387151926867 9822.317118007753 8841.128235799773 6701.657286573584 1.3644560507796093 1.2602403788801595 1.5884690216496502 1.5926001636325209 1.3837571089053171 1.506196825644671 1.61682203201214 1.4656549414554882 1.319245055027285 1.0 12.710302195674364 -8.634974886970173 2.4182470564842684 1.0007419694223978 1.475831812162998 0.6431352847943556 0.10717087529457982 0.30414917954049414 3.836330248768148 0.11070083017680019 0.030049702477771244 2.317528656929271e-09 8.634974886970173 0.4750898427406003 QTAGQGS(ph)PCEEQEEPR ddPTM_PC-9_AZD4547_30min_R2 1 QTAGQGSPCEEQEEPR 16 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 QT(0.004)AGQGS(0.996)PCEEQEEPR 140.8 5.7247e-07 0.0 2553.8 3391.1 4691.8 2805.2 4651.1 6330.9 5391.8 6025.2 4012.6 5774.9 True False 3365.855277660119 4487.206758425177 4629.583666432339 2158.504479907966 4005.375048829967 5935.027822192478 5871.659754699365 5094.143785322106 4224.697844114742 5572.722508742756 0.6039875971537436 0.8052090789350144 0.8307579749699047 0.38733392458023885 0.7187465448972458 1.0650140596236974 1.0536429448061737 0.9141211997062777 0.7581030344659783 1.0 12.444166601503943 -6.654267497807956 6.231700824204008 0.9576806170671985 0.6653176695069859 0.5222374706410928 0.13888912922923657 0.1885604983860566 9.74700605498415 0.048665116068392744 0.048506412601040966 2.2168305724195e-07 6.654267497807956 -0.29236294756021264 QTAGQGS(ph)PCEEQEEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QTAGQGSPCEEQEEPR 16 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 QT(0.017)AGQGS(0.983)PCEEQEEPR 102.33 0.0015168 2134600.0 3393.4 7109.5 6045.7 4575.9 6993.8 6916.2 6795.2 5160.9 6243.7 5387.1 True False 3967.8355972949407 7815.284174951363 6189.852416444932 4319.527158267965 5623.41509541338 6553.502296725739 6151.509463012324 5025.431843425549 6335.002300580092 6363.738585739862 0.6235070067438403 1.22809635714204 0.9726754694662376 0.6787719357214557 0.8836653202591586 1.0298195327210813 0.9666502449985752 0.7896980329592344 0.9954843705830149 1.0 12.635658857477049 QTAGQGS(ph)PCEEQEEPR ddPTM_PC-9_Lapatinib_30min_R1 1 QTAGQGSPCEEQEEPR 16 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 QT(0.071)AGQGS(0.929)PCEEQEEPR 121.48 0.00085038 0.0 3341.1 5971.9 4214.6 5416.0 4968.4 5363.6 4739.9 4621.9 6044.0 4517.7 True False 3293.4553013172986 5958.072432462439 3868.091856826475 5814.310707246362 4676.168480250231 5134.211331162279 4985.308829491182 4836.650347075496 5363.261073858438 5298.578425543141 0.6215733800297004 1.1244662160212708 0.7300244605570727 1.0973340847833832 0.8825326539865062 0.9689790201861525 0.940876670893128 0.9128203753216517 1.012207547594932 1.0 12.371389630466984 -4.741817749208237 24.97326802569112 0.9543840616034897 0.6215722275998011 0.48143375347724204 0.10602354263470724 1144.032913876166 1455982.1375780671 0.023675507946039055 0.9114962318943693 1.8121003773024338e-05 4.741817749208237 -0.3328118340036885 QTATQLLK ddPTM_PC-9_Lapatinib_30min_R1 1 QTATQLLK 8 0 P62424;Q5T8U3 P62424 RPL7A 60S ribosomal protein L7a 0 102.07 0.02024 6619000.0 79503.0 53047.0 61869.0 56186.0 51263.0 62272.0 40875.0 45554.0 65387.0 47486.0 False True 78369.27264093547 52924.17293069796 56782.36964124639 60318.105871001484 48247.81112693572 59608.77172312206 42991.30749708898 47670.605143053115 58022.427504364976 55693.891828882304 1.4071430468842534 0.9502688929210726 1.0195439351896685 1.0830291058905872 0.8663034588276857 1.0702928052912535 0.7719214097872419 0.8559395577798643 1.0418095342059597 1.0 15.765231489674921 QTDAQSASS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 QTDAQSASSPK 11 0 F5H4N6;Q9Y3R0-3;Q9Y3R0-2;Q9Y3R0;F5H4P8;H0YFK8;F5H4Q7 F5H4N6 GRIP1 Glutamate receptor-interacting protein 1 1 QTDAQSAS(0.077)S(0.923)PK;QTDAQSAS(0.035)S(0.965)PK 135.04 0.00024047 19026000.0 107242.0 77750.0 61224.0 70115.0 71752.0 73093.0 77073.0 61005.0 90145.0 94120.0 True False 141342.72522782756 102881.16701588209 60412.12975694907 53951.07001595141 61790.47332967422 68522.48315524109 83932.34768981476 51578.079005439606 94909.88066533518 90824.88744789851 1.5562113997543734 1.1327420259661718 0.6651495141307425 0.5940119666748865 0.68032534986757 0.7544461114201639 0.924111772095092 0.5678848656435413 1.0449765844166887 1.0 16.470800052373427 -4.949693168947708 2.746799475336768 0.7588613462685716 1.5830392969615947 0.7013862408726791 0.1587795810167865 0.16421744495309212 2.156015621972809 0.04028242315897211 0.2608121820031483 1.1228114456021692e-05 4.949693168947708 0.8241779506930231 QTDAQSASS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 QTDAQSASSPK 11 0 F5H4N6;Q9Y3R0-3;Q9Y3R0-2;Q9Y3R0;F5H4P8;H0YFK8;F5H4Q7 F5H4N6 GRIP1 Glutamate receptor-interacting protein 1 1 QTDAQSAS(0.03)S(0.97)PK 164.92 3.5148000000000003e-13 0.0 42242.0 69064.0 35867.0 52717.0 65523.0 42149.0 69745.0 68497.0 55590.0 50761.0 True False 41639.62133376594 68904.08655127934 32918.1537106238 56593.98403875677 61669.06596317444 40346.38552411789 73356.05483509415 71679.62068059242 49328.86881134855 59534.97121521906 0.6994144867096452 1.1573716278822224 0.5529213005180534 0.9506006786191158 1.0358460700390804 0.6776921983932034 1.2321506727518494 1.203991859196008 0.828569625624317 1.0 15.86144974507462 -7.266653807598285 24.99880957638812 1.0831773539674217 0.8599217624920491 0.22699436304583098 0.19733239448778378 669.5330805033033 3209833.2444279473 0.07819146483885567 0.05448902588292262 5.411855503258642e-08 7.266653807598285 -0.22325559147537255 QTDFEHR ddPTM_PC-9_AZD4547_30min_R2 4 QTDFEHR 7 0 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 0 ;;; 180.93 0.00016973 39770300.0 118934.0 103715.0 142364.0 199377.0 168285.0 158743.0 141942.0 178092.0 139475.0 159939.0 False True 156752.53801911997 137238.84549263283 140476.1603410147 153413.71299394342 144921.5325605446 148816.77511543402 154574.56302191087 150571.97354703335 146847.36375614392 154339.58429164253 1.0156340561532022 0.8892005646024297 0.9101758371693468 0.9940010768983959 0.938978378266839 0.9642165086710839 1.0015224787040007 0.9755888240732213 0.9514562607519974 1.0 17.235748599451227 -6.541673795236903 1.131029828324619 0.9796691389827502 0.940683314458338 0.12149809986036875 0.03711431418110503 0.953351089755644 2.5830865965289105 0.017714770160440974 0.019863782185187744 2.872937676166676e-07 6.541673795236903 -0.03898582452441224 QTDFEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QTDFEHR 7 0 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 0 ;;; 199.02 0.00011935 31638900.0 110806.0 108618.0 113471.0 129206.0 146018.0 117344.0 138923.0 112961.0 115469.0 102327.0 False True 129563.26728174195 119400.87720864564 116176.57898116366 121967.00671150409 117406.82109898377 111190.27406769396 125763.20772457919 109995.89344207273 117157.51567911358 120878.07507991377 1.071850848022574 0.9877794391555992 0.9611054685008683 1.0090085123449426 0.971283014073188 0.9198547709680592 1.040413719704221 0.90997390030701 0.9692205604834417 1.0 16.8831930660716 -4.763262410999494 3.3264683010139526 0.9712150625085113 1.0877849883877027 0.39239542966524654 0.036805425157628045 0.33790633476414367 5.715895692954204 0.008931523180762888 0.10461369910794391 1.724795414886386e-05 4.763262410999494 0.11656992587919135 QTDFEHR ddPTM_PC-9_Lapatinib_30min_R1 4 QTDFEHR 7 0 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 0 ;;; 180.93 0.00014065 49989800.0 117986.0 124035.0 143190.0 125515.0 139531.0 138480.0 117777.0 118003.0 144384.0 111509.0 False True 116303.49800401778 123747.80457818741 131417.47092938412 134745.79180576577 131324.06090850077 132557.53321264664 123874.91677271322 123485.85017113079 128121.9534890763 130783.1820735974 0.8892848159832104 0.94620579355952 1.0048499267698638 1.0302990772157419 1.0041356910447323 1.0135671201060907 0.9471777242964114 0.9442028264891117 0.979651599369837 1.0 16.996817505341625 -4.923821124702079 2.9104604696629064 0.9894444411170786 0.8857083867836189 0.5934402627654831 0.02615169484060322 0.24874886561392878 3.6554897959573145 0.007852372808301243 0.05236804018327803 1.1917327525935389e-05 4.923821124702079 -0.10373605433345978 QTDLELS(ph)PLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QTDLELSPLTK 11 0 J3KTC5;Q8WVK7 J3KTC5 SKA2 Spindle and kinetochore-associated protein 2 1 QTDLELS(0.5)PLT(0.5)K;QTDLELS(0.5)PLT(0.5)K 87.083 0.010565999999999999 6442700.0 38468.0 58065.0 53639.0 44814.0 52486.0 41726.0 53203.0 36098.0 37342.0 39922.0 True False 44979.87262236749 63829.30946178361 54917.9571870403 42303.216868948286 42201.745073903556 39537.81510557506 48163.226683636145 35150.465748992545 37888.05610587663 47159.5425776219 0.9537809351804718 1.3534760087361797 1.1645142040266505 0.8970234772595519 0.8948718067916351 0.8383841942592655 1.021282736242877 0.7453521350665541 0.8034016878665663 1.0 15.525262104563543 -5.764969633335049 5.458931654721419 0.8778385199651072 1.179634651937355 0.5198656057077501 0.11903643513326807 0.11734347814017983 10.913149442518051 0.03227923822887209 0.05234992709355951 1.7180285106554377e-06 5.764969633335049 0.30179613197224786 QTDLELS(ph)PLTKEEK ddPTM_PC-9_AZD4547_30min_R2 1 QTDLELSPLTKEEK 14 1 J3KTC5;Q8WVK7 J3KTC5 SKA2 Spindle and kinetochore-associated protein 2 1 QT(0.014)DLELS(0.739)PLT(0.247)KEEK 55.707 0.034755 5844800.0 35594.0 25751.0 33916.0 47610.0 51506.0 40099.0 33621.0 35622.0 33578.0 40536.0 True False 46912.15159880733 34074.50716174893 33466.25167967927 36634.250067167464 44355.28095827572 37591.60319103071 36613.203867492724 30117.438412126376 35352.864529154365 39116.84697819813 1.1992825399489362 0.8710954433709965 0.855545737066481 0.9365338184743175 1.133917592667866 0.9610080079302525 0.9359957843202235 0.7699352258353646 0.9037759241908829 1.0 15.255502465784307 -7.528622965779032 24.23531385090002 0.8727064257195984 0.981926920760066 0.13084323077647753 0.11350307109306979 206.15342697888283 869751.051977532 0.053802241105966105 0.031192938893404205 2.960581590098129e-08 7.528622965779032 0.1092204950404676 QTDLELSPLT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 2 QTDLELSPLTK 11 0 J3KTC5;Q8WVK7 J3KTC5 SKA2 Spindle and kinetochore-associated protein 2 1 QT(0.008)DLELS(0.056)PLT(0.936)K;QT(0.001)DLELS(0.104)PLT(0.895)K 124.42 0.0012532 6412900.0 51269.0 53469.0 48574.0 49925.0 60358.0 56004.0 59694.0 56079.0 59107.0 47984.0 True False 50537.8946584169 53345.1958156256 44580.4332210623 53596.651044917766 56807.86110839375 53608.83947170039 62784.66323501476 58684.63506645468 52449.747235696705 56277.97046533901 0.8980049252050168 0.9478876969893634 0.7921471377245011 0.9523557904051881 1.009415596167973 0.9525723658552594 1.115617047236683 1.0427638840067608 0.9319765229984606 1.0 15.780282681606733 -5.99779892703078 6.464250312533103 1.0108639533949264 0.8835778267707488 0.4929802220475754 0.05871281276911262 0.1227947210679016 24.753872693055577 0.017296323840177534 0.02458615752221261 1.005081022643791e-06 5.99779892703078 -0.1272861266241776 QTDPST(ph)PQQESSKPLGGIQPSSQTIQPK ddPTM_PC-9_AZD4547_30min_R2 1 QTDPSTPQQESSKPLGGIQPSSQTIQPK 28 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YF61 Q14004 CDK13 Cyclin-dependent kinase 13 1 QTDPS(0.197)T(0.602)PQQES(0.078)S(0.123)KPLGGIQPSSQTIQPK 115.38 2.7778e-12 23644000.0 54338.0 54152.0 64289.0 92729.0 98570.0 74301.0 51612.0 91282.0 54218.0 76228.0 True False 71616.35369938727 71655.57499992348 63436.48585431365 71351.7616987686 84885.25694205033 69654.94672427652 56205.368014307576 77176.46435168482 57083.85279175925 73559.28092199737 0.9735869193083821 0.9741201124016888 0.8623858887579667 0.9699899292712005 1.1539707278006575 0.9469226160345283 0.7640826189411507 1.0491737192689952 0.7760251606087782 1.0 16.16661975631753 -7.005218933166031 24.997264982807632 0.8948588133261239 0.985477491699441 0.13887907471829797 0.10494920822006569 471.1317393246512 2256598.594001222 0.037292565033733675 0.03198511714661756 9.880548785265957e-08 7.005218933166031 0.09061867837331705 QTDPST(ph)PQQESSKPLGGIQPSSQTIQPK ddPTM_PC-9_Lapatinib_30min_R1 1 QTDPSTPQQESSKPLGGIQPSSQTIQPK 28 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YF61 Q14004 CDK13 Cyclin-dependent kinase 13 1 QTDPS(0.202)T(0.558)PQQES(0.199)S(0.042)KPLGGIQPSSQTIQPK 101.2 5.3845e-10 16407000.0 107380.0 85761.0 98164.0 86075.0 110200.0 100470.0 90160.0 84681.0 102150.0 84414.0 True False 105848.74150891989 85562.4256736401 90093.33484399799 92405.24263778259 103718.25266153591 96173.13230700897 94828.043643732 88615.58840318896 90644.79131281274 99004.84742541536 1.0691268585476115 0.8642246101949501 0.9099891286825043 0.9333405892817063 1.0476078228358603 0.9713982174404173 0.9578121284937091 0.8950631277922723 0.9155591233156477 1.0 16.595211542978085 -4.735222886438806 24.80556037439654 0.9437561085685566 1.0691275410923111 0.35497544993949137 0.05064607063925234 3047.488255559361 2883310.2461973135 0.013463402187659216 1.075286415865153 1.8398275320606654e-05 4.735222886438806 0.1253714325237545 QTDPSTPQQES(ph)SKPLGGIQPSSQTIQPK ddPTM_PC-9_AZD4547_30min_R2 3 QTDPSTPQQESSKPLGGIQPSSQTIQPK 28 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YF61 Q14004 CDK13 Cyclin-dependent kinase 13 1 QT(0.001)DPS(0.03)T(0.065)PQQES(0.43)S(0.43)KPLGGIQPS(0.017)S(0.021)QT(0.005)IQPK;QTDPS(0.035)T(0.12)PQQES(0.419)S(0.419)KPLGGIQPS(0.003)S(0.003)QTIQPK;QTDPS(0.031)T(0.087)PQQES(0.717)S(0.165)KPLGGIQPSSQTIQPK 95.209 7.478400000000001e-10 43854200.0 138630.0 125437.0 170234.0 228064.0 218663.0 224897.0 162540.0 219927.0 178023.0 201242.0 True False 182711.45631686974 165982.05719577102 167976.5859310804 175487.36835367535 188305.41684812368 210834.15503761225 177005.74511829746 185942.3355696963 187432.9323388424 194196.57883329736 0.9408582654471647 0.8547115412277869 0.864982209986692 0.9036583929952627 0.9696639249745446 1.0856738893355942 0.9114771546528794 0.9574954238988592 0.9651711346559765 1.0 17.56715825941785 -6.2282858096893365 3.9067273324148446 0.9817529851731096 0.8844525798417937 0.48043153297610075 0.04637286640373585 0.2026618568629119 6.848402406526893 0.014721820466611232 0.018661891909031426 5.911724548692162e-07 6.2282858096893365 -0.0973004053313159 QTDPSTPQQES(ph)SKPLGGIQPSSQTIQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QTDPSTPQQESSKPLGGIQPSSQTIQPK 28 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YF61 Q14004 CDK13 Cyclin-dependent kinase 13 1 QTDPS(0.003)T(0.009)PQQES(0.494)S(0.494)KPLGGIQPSSQTIQPK;QTDPS(0.013)T(0.144)PQQES(0.42)S(0.42)KPLGGIQPS(0.002)S(0.001)QTIQPK;QT(0.002)DPS(0.046)T(0.299)PQQES(0.324)S(0.324)KPLGGIQPS(0.002)S(0.003)QT(0.001)IQPK;QTDPS(0.022)T(0.07)PQQES(0.731)S(0.166)KPLGGIQPS(0.004)S(0.005)QT(0.002)IQPK 112.26 2.8201e-11 59198000.0 234188.0 201248.0 221317.0 254138.0 311546.0 256606.0 271030.0 234149.0 239866.0 215675.0 True False 273831.4029761622 221226.57143830264 226594.03662939643 239899.47178651244 250500.79775167347 243149.12963095424 245356.07631272558 228002.83685137233 243373.58646811076 254775.17021763933 1.0747962713252013 0.868320767872795 0.8893882258456763 0.9416124482679397 0.9832229629664676 0.9543674504200953 0.9630297807401421 0.8949178079504491 0.9552484500754572 1.0 17.958865157253257 -6.0066191389375625 24.73305434864742 0.9540686283369982 0.9330697774364417 0.0016701718404934507 0.05720767472028127 1306.7758564487613 4882939.144625782 0.01619586583281619 0.023083718278901055 9.848744275614642e-07 6.0066191389375625 -0.02099885090055653 QTDPSTPQQES(ph)SKPLGGIQPSSQTIQPK ddPTM_PC-9_Lapatinib_30min_R1 3 QTDPSTPQQESSKPLGGIQPSSQTIQPK 28 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YF61 Q14004 CDK13 Cyclin-dependent kinase 13 1 QT(0.003)DPS(0.07)T(0.2)PQQES(0.581)S(0.146)KPLGGIQPSSQTIQPK;QTDPS(0.003)T(0.007)PQQES(0.768)S(0.191)KPLGGIQPS(0.011)S(0.009)QT(0.011)IQPK;QTDPS(0.022)T(0.075)PQQES(0.855)S(0.048)KPLGGIQPSSQTIQPK 119.52 1.0328e-12 40381800.0 175737.0 138368.0 172883.0 147137.0 173495.0 172933.0 133525.0 137392.0 170507.0 124659.0 True False 173230.9581537811 138047.61739730454 158669.2270876787 157957.94581464343 163290.3652042938 165537.05871651246 140438.27115715735 143775.73389415533 151302.7061416911 146206.1420523233 1.18484049795792 0.9441984820849795 1.085243238487855 1.0803783178829414 1.1168502424874636 1.1322168576014484 0.9605497360493803 0.9833768395496122 1.034858755027842 1.0 17.157644393950825 -7.267223363122809 24.95613536932438 0.9933110680434762 1.084447872597312 0.377409587077709 0.06003374416128027 547.4469181274031 2362055.0420954595 0.024553256142107835 0.017053065482825404 5.404762776926767e-08 7.267223363122809 0.09113680455383566 QTDTSEEGS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QTDTSEEGSPR 11 0 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 QTDTSEEGS(1)PR;QTDT(0.004)S(0.004)EEGS(0.993)PR 99.941 0.0043534 2328500.0 6638.9 9687.5 9429.4 6891.9 8741.2 6238.1 9158.9 5444.6 5662.1 5287.3 True False 7762.734645748034 10649.210977542913 9654.232657198641 6505.7691868412685 7028.424609229233 5910.963054452571 8291.302687306263 5301.685019030549 5744.897500859196 6245.845635756229 1.242863672663941 1.7050070716730956 1.5457046523740632 1.0416154298782263 1.1252959197378967 0.9463831479621395 1.327490810826351 0.848833821425149 0.9197949862818888 1.0 12.608681198676202 -5.763766397218079 24.998223554078756 1.0365101986556229 1.518573400187943 0.6358915340301005 0.16198423345370608 35.99186249526864 386653.350728802 0.044508948266657196 0.06973197947055722 1.7227950004969715e-06 5.763766397218079 0.4820632015323201 QTDTSEEGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 QTDTSEEGSPR 11 0 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 QTDTS(0.001)EEGS(0.999)PR;QTDTSEEGS(1)PR 97.631 0.01311 0.0 1719.9099999999999 1983.39 4278.8 1734.2199999999998 4551.7 4152.1 3372.4 5370.5 5281.6 3354.5 True False 1695.3837680071344 1978.7975823141192 3927.013580645642 1861.7603239883272 4283.977954986507 3974.5243620178426 3547.0063707200684 5620.033035974157 4686.730590286359 3934.320855409715 0.4309215822283461 0.502957856015546 0.9981426845870932 0.4732100894690364 1.0888735597392905 1.0102186649451448 0.9015549318614706 1.4284633212480822 1.191242596251924 1.0 11.941898903090081 -5.788622435667599 0.5165363535503354 1.2028181016789412 0.3124823170780894 0.5935141429210001 0.20073728962246287 1.2037470528944905 0.5007289859432188 0.1463582577718281 0.5834075574971666 1.626962580062048e-06 5.788622435667599 -0.8903357846008518 QTDTSEEGS(ph)PRENPR ddPTM_PC-9_AZD4547_30min_R2 3 QTDTSEEGSPRENPR 15 1 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 QT(0.001)DT(0.007)S(0.023)EEGS(0.969)PRENPR;QTDTSEEGS(1)PRENPR;QTDT(0.079)S(0.079)EEGS(0.841)PRENPR 87.99 0.008945100000000001 14779900.0 10657.7 8865.599999999999 14067.1 18700.7 18975.0 15610.7 11630.1 17131.0 9452.6 14243.8 True False 14046.6269060687 11731.23182374281 13880.561062720137 14389.54253793486 16340.648782341515 14634.560461214056 12665.156369510949 14483.797581217716 9952.245138134629 13745.12889747529 1.0219348985987893 0.8534828528161426 1.0098531025976571 1.0468830554639568 1.188831978530443 1.0647088557970625 0.9214287085977992 1.0537403969982488 0.7240561519916092 1.0 13.746632815601949 -8.234032513021228 24.98490850291531 0.8620279798344127 1.0189260110842089 0.2701324822461111 0.10392247105728161 863.3221626776468 787032.5018855659 0.07208772608058604 0.02723271028001014 5.834014268755732e-09 8.234032513021228 0.15689803124979618 QTDTSEEGS(ph)PRENPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QTDTSEEGSPRENPR 15 1 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 QT(0.017)DT(0.056)S(0.056)EEGS(0.87)PRENPR;QT(0.003)DT(0.001)S(0.003)EEGS(0.993)PRENPR 56.46 0.031342 8575000.0 7889.299999999999 7795.1 10186.4 10951.8 13716.599999999999 11683.4 11151.6 12736.0 12051.1 9389.8 True False 9224.8026692223 8568.946011978807 10429.282408137122 10338.206152214665 11028.930695436986 11070.701936549767 10095.239717407605 12401.69349490745 12227.324539058698 11092.0964103841 0.8316554714207411 0.7725271846678873 0.9402444787960488 0.9320335642355521 0.9943053402521835 0.9980711965490758 0.9101290994871568 1.1180657863104528 1.102345678100294 1.0 13.437244440723806 -5.348456447485773 0.47151002939843145 1.0562032047281857 0.6895652778644101 0.6690711492805238 0.05887715583514512 1.7758366921707462 0.45043368001842515 0.045428337053283224 0.34293018957340554 4.482740021702352e-06 5.348456447485773 -0.3666379268637756 QTDTSEEGS(ph)PRENPR ddPTM_PC-9_Lapatinib_30min_R1 2 QTDTSEEGSPRENPR 15 1 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 QTDT(0.001)S(0.001)EEGS(0.998)PRENPR;QT(0.009)DT(0.023)S(0.023)EEGS(0.946)PRENPR 72.793 0.008924799999999998 8039700.0 11125.3 10599.7 10056.599999999999 9903.3 12685.3 8029.700000000001 10273.8 9279.900000000001 13747.0 7414.700000000001 True False 10966.651181869844 10575.157045893624 9229.785167598611 10631.621718440343 11939.175594259372 7686.288449144927 10805.72709391052 9711.078031940528 12198.668097672406 8696.321015533289 1.2610678886256972 1.2160495256562374 1.0613436591303902 1.2225424635831907 1.3728995943150817 0.8838551883509991 1.242563041843721 1.1166880816145919 1.4027389370612304 1.0 13.086189481578584 QTDVGITHFR ddPTM_PC-9_Lapatinib_30min_R1 1 QTDVGITHFR 10 0 Q6P2Q9 Q6P2Q9 PRPF8 Pre-mRNA-processing-splicing factor 8 0 87.641 0.0098631 0.0 21705.0 18286.0 17389.0 16243.0 18903.0 19490.0 15865.0 15528.0 18325.0 15378.0 False True 21395.48271979048 18243.659890488492 15959.34354348112 17437.56440505957 17791.162704727893 18656.458133409054 16686.41207195882 16249.48756775099 16261.04552919522 18036.066810103024 1.1862610038573187 1.011509886416543 0.8848571981637031 0.9668163568396076 0.9864214239194353 1.0343972624318798 0.9251691207204785 0.9009440771559313 0.9015849020966415 1.0 14.138597138750727 -4.810847470959164 3.315388229160927 0.9502551462359294 1.2103038191566957 0.7047606501251777 0.0459668845148609 0.1692724616976999 3.0018914709004845 0.012487656669196134 0.10895753285450918 1.5457972453573587e-05 4.810847470959164 0.2600486729207663 QTELFAHFIQPSAQKS(ph)PTSPLNMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QTELFAHFIQPSAQKSPTSPLNMK 24 1 A0A0A0MRP6;B7ZLQ5;P28370-2;P28370 A0A0A0MRP6 SMARCA1 Probable global transcription activator SNF2L1 1 QTELFAHFIQPS(0.201)AQKS(0.487)PT(0.156)S(0.156)PLNMK;QTELFAHFIQPS(0.048)AQKS(0.463)PT(0.245)S(0.245)PLNMK 60.761 0.0018440000000000002 16629100.0 35627.0 26589.0 33780.0 47735.0 53051.0 52490.0 46738.0 42340.0 42105.0 38773.0 True False 41657.94743467519 29228.580199420732 34585.44331136338 45060.56270895805 42656.037379789996 49737.33199663606 42310.63828618287 41228.61986293823 42720.705970165924 45802.23797310086 0.9095177283507507 0.6381474245120151 0.7551037862314723 0.9838070081951369 0.9313090204203865 1.0859148853347784 0.9237679239829161 0.9001442219297522 0.9327209293846146 1.0 15.483130472059722 -5.757881662390781 24.88916904188022 0.9630886781177005 0.7546453615314894 0.5687831255288681 0.07866109743090624 58.4779207143172 409092.76978917763 0.021340577983571085 0.03517036203692408 1.7462979235733925e-06 5.757881662390781 -0.20844331658621107 QTEPVS(ph)PVLK ddPTM_PC-9_AZD4547_30min_R2 1 QTEPVSPVLK 10 0 Q8IYH5-4;Q8IYH5-2;Q8IYH5 Q8IYH5-4 ZZZ3 ZZ-type zinc finger-containing protein 3 1 QT(0.469)EPVS(0.531)PVLK 88.561 0.009909200000000002 4931400.0 41818.0 46603.0 50883.0 48352.0 48806.0 53131.0 46101.0 66172.0 53154.0 43291.0 True False 55115.254131565045 61666.508378664286 50208.25817363844 37205.19343095318 42030.12935288325 49808.71017089334 50203.89969052921 55946.63788128758 55963.6119239583 41775.39526675488 1.3193233428344389 1.476144222810954 1.2018619537418114 0.8906006321036848 1.006097706185705 1.1922977593112427 1.2017576223984117 1.3392246207137688 1.3396309374598423 1.0 15.35036585826534 -5.389527985456971 5.577272235489744 1.1448582895512216 1.394545311494418 0.3422111957053944 0.14109718032603194 0.27300141315632875 11.116414193726488 0.041402356557400884 0.08805945192771499 4.078232812425111e-06 5.389527985456971 0.24968702194319636 QTFLSHGDDFR ddPTM_PC-9_AZD4547_30min_R2 1 QTFLSHGDDFR 11 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 0 94.538 0.0055323 2295500.0 13083.0 12450.0 20609.0 24512.0 18029.0 18639.0 16541.0 20926.0 16011.0 15081.0 False True 17243.121856694852 16474.21902698046 20335.711194318606 18861.13710662485 15525.984553192893 17473.500383491384 18013.116955837053 17692.367531642154 16857.30877289566 14553.01878029914 1.1848484576985074 1.1320138643181101 1.397353463313582 1.296029187577064 1.0668566286886736 1.2006787490129394 1.237758105570643 1.2157180443959053 1.158337594926759 1.0 13.829030826678288 -10.267088269355526 0.40039413143513 0.928475398736641 1.2271807450022334 0.371542047969333 0.08424803284097666 13.3036486140675 1.754442866814667 1.259505819280941 0.059575342678582874 5.4064442704041004e-11 10.267088269355526 0.2987053462655924 QTGIET(ph)PNK ddPTM_PC-9_AZD4547_30min_R2 2 QTGIETPNK 9 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 QTGIET(1)PNK;QTGIET(1)PNK 144.28 0.0013631 51499000.0 131290.0 125180.0 159154.0 144986.0 151764.0 183744.0 160720.0 162589.0 170017.0 168588.0 True False 173037.48899835383 165641.98697167973 157043.51397062364 111561.71771137032 130694.18823732714 172254.45863320155 175023.76864410422 137464.60597353365 179003.75152341535 162685.78543419344 1.0636300432550554 1.0181712343804128 0.9653179812328957 0.6857496333414891 0.8033534576393158 1.0588168976992685 1.0758393437815224 0.8449699868163234 1.1003035762815463 1.0 17.311728676403142 -6.780240307438595 24.993906155167682 1.0100374184631766 0.9043280693728857 0.17101506062816363 0.1192622812944325 519.8758808355011 691117.154298715 0.045966355914498984 0.0406060891778109 1.6586688650053405e-07 6.780240307438595 -0.10570934909029095 QTGIET(ph)PNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QTGIETPNK 9 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 QTGIET(1)PNK 83.226 0.035764 14088000.0 26274.0 29536.0 32705.0 30735.0 36559.0 26552.0 30692.0 30251.0 21000.0 18780.0 True False 30721.669264845663 32468.138883376232 33484.81123440318 29013.017594214445 29395.52639097741 25159.56637787542 27784.631569162648 29456.94330358392 21307.085271903194 22184.66533760181 1.38481553800021 1.4635397194089959 1.5093674267715111 1.3077960452727202 1.3250380811989793 1.1340971790650054 1.252425093925992 1.3278065210952716 0.9604420417282037 1.0 14.437275169379935 -7.1216178658110705 0.3332467899997869 0.9762545237405267 1.5261331980017747 0.6971373059691814 0.09581437676252164 1.0027633796033018 0.2707722094958546 0.1273514685671871 0.19936470812998144 7.55756923052565e-08 7.1216178658110705 0.549878674261248 QTGIET(ph)PNK ddPTM_PC-9_Lapatinib_30min_R1 3 QTGIETPNK 9 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 QT(0.001)GIET(0.999)PNK;QT(0.015)GIET(0.985)PNK;QT(0.1)GIET(0.9)PNK 112.84 0.005234600000000001 76800300.0 135895.0 244773.0 226060.0 243473.0 263534.0 216081.0 182517.0 193524.0 215413.0 189617.0 True False 133957.11237990894 244206.24315730858 207474.2194168347 261378.8166221181 248033.44824777896 206839.71933941316 191966.8371974602 202515.8315340955 191150.9195405472 222392.04580122957 0.6023466886924438 1.098088927944735 0.9329210434183955 1.1753064983975832 1.1152981994215174 0.9300679734035234 0.863191111470943 0.9106253364614527 0.8595222857538476 1.0 17.76274566318017 -6.984653306506123 24.62103367253507 0.9002785886896869 1.0011783499085074 0.048796068838455775 0.15150885730600896 520.8086063492051 835540.4849370483 0.05317739034438379 0.046881193913513274 1.035968841554848e-07 6.984653306506123 0.1008997612188205 QTGIET(ph)PNKSGK ddPTM_PC-9_Lapatinib_30min_R1 2 QTGIETPNKSGK 12 1 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 QT(0.004)GIET(0.991)PNKS(0.006)GK;QT(0.012)GIET(0.985)PNKS(0.003)GK 118.16 0.006155 9589900.0 79297.0 30529.0 32285.0 38159.0 28116.0 29227.0 18213.699999999997 16366.199999999999 32750.0 20412.9 True False 78166.21023871115 30458.31197619616 29630.65192370397 40965.3401546924 26462.27215818281 27977.029341464648 19156.716265681454 17126.633399750528 29061.350127211103 23941.242566520472 3.2649186867192554 1.2722109928742455 1.2376405210120376 1.7110782801214541 1.1053006996047796 1.1685704809903157 0.8001554728187034 0.7153610908942746 1.2138613961436826 1.0 14.547210410612674 -3.0810789967249095 1.356155202620502 1.0899542175621337 199.9999999788908 0.8498444406199337 0.26720244542808524 51.69013717354688 1.357390559810972 0.08376080761745548 30908.719600311044 0.0008296998341414996 3.0810789967249095 198.91004576132866 up QTGRLGSSGLGS(ph)AS(ph)S(ph)IQAAVR ddPTM_PC-9_Lapatinib_30min_R1 1 QTGRLGSSGLGSASSIQAAVR 21 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 3 QTGRLGSS(0.001)GLGS(1)AS(1)S(0.999)IQAAVR 73.76 0.02605 64448000.0 22757.0 25336.0 56967.0 28181.0 34280.0 43562.0 29882.0 37594.0 58662.0 22779.0 True False 22432.481006877322 25277.3360486392 52283.39315897918 30253.52474906013 32263.71779707307 41698.95480798181 31429.143746251066 39340.75448364441 52054.867821754444 26716.319798890407 0.8396546072116189 0.9461383992599546 1.9569833552131173 1.1323986603243397 1.2076407993294442 1.560804598907132 1.176402438016796 1.4725364413880957 1.9484295821281645 1.0 14.70543366829099 -5.032156829148521 24.253699775799955 1.4272831699710424 0.866275242003433 0.3300039721283031 0.30878342765190964 419.5637591091476 316449.4841484959 0.07594582919179266 0.20139843739418603 9.286309860055282e-06 5.032156829148521 -0.5610079279676095 QTGYGWICQECDS(ph)SSSKEDENEAERK ddPTM_PC-9_Lapatinib_30min_R1 1 QTGYGWICQECDSSSSKEDENEAERK 26 2 A0A0U1RRH6;O94880-2 A0A0U1RRH6 PHF14 PHD finger protein 14 1 QT(0.001)GY(0.002)GWICQECDS(0.406)S(0.406)S(0.093)S(0.093)KEDENEAERK 41.423 0.025309 11069000.0 12617.0 19724.0 20309.0 20727.0 16724.0 18717.0 19473.0 12738.0 16380.0 14717.0 True False 12437.079266325574 19678.33028983895 18639.272415007094 22251.33272324507 15740.327200649066 17916.51754145804 20481.216657879228 13329.853982355236 14535.111910953212 17260.813840830157 0.7205384045627025 1.1400580801868216 1.079860578237407 1.2891241935887128 0.9119110689564124 1.0379879944639012 1.1865730577217202 0.7722610361988667 0.8420872877135525 1.0 14.075212868194333 -7.768955660595801 24.999732511110572 0.8553806144348313 1.0598885435966066 0.21883151311072258 0.15522883333746737 240.34897061679635 799403.9093401033 0.08117913858007518 0.040194168653693 1.7023322995668214e-08 7.768955660595801 0.2045079291617753 QTIDNSQGAYQEAFDISK ddPTM_PC-9_Lapatinib_30min_R1 2 QTIDNSQGAYQEAFDISK 18 0 P27348 P27348 YWHAQ 14-3-3 protein theta 0 ; 201.4 1.6563e-14 10359100.0 38922.0 36139.0 34807.0 36445.0 40793.0 36189.0 42683.0 31625.0 35731.0 43648.0 False True 38366.96514257937 36055.32236587352 31945.302818905475 39125.286876955994 38393.635942123736 34641.28083067932 44892.916890477034 33094.41295273861 31706.59851588945 51192.49864269586 0.7494645926616353 0.7043087038498734 0.6240231218614962 0.7642777343226709 0.7499855830459984 0.6766866581852601 0.8769432647508084 0.6464699678701954 0.6193602452810407 1.0 15.643644803762166 -11.08423205147647 5.8657095123147736 1.0007644268092573 0.714036901452154 0.5762325404308253 0.07398051923160522 0.0007445314448000088 5.567712672640113e-05 0.07211247950869805 0.017445082727956866 8.236978805838374e-12 11.08423205147647 -0.2867275253571032 QTIGNSCGTIGLIHAVANNQDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QTIGNSCGTIGLIHAVANNQDK 22 0 P09936;D6RE83;D6R956;D6R974 P09936 UCHL1 Ubiquitin carboxyl-terminal hydrolase isozyme L1;Ubiquitin carboxyl-terminal hydrolase 0 ; 102.15 5.8806000000000006e-05 11855200.0 31858.0 39997.0 37901.0 39530.0 46633.0 36710.0 37185.0 33009.0 31243.0 31545.0 False True 37250.930175818394 43967.63782903575 38804.70358034292 37315.26225798916 37495.59840779151 34784.86297573843 33662.56760391352 32142.548725926474 31699.869769051034 37263.85878991738 0.9996530521926923 1.1799002909739513 1.04134957678732 1.0013794456543423 1.0062188840715776 0.9334745274729922 0.9033569978271205 0.8625662980083909 0.8506867189403419 1.0 15.185489457179095 -6.418373846641796 0.9879705599104961 0.8907011977739451 1.0873462026795555 0.5912505297724825 0.058651872410118426 0.3380759981287005 0.7080804507013084 0.028185009671904092 0.03701539823278132 3.8161562944716677e-07 6.418373846641796 0.19664500490561043 QTIGNSCGTIGLIHAVANNQDK ddPTM_PC-9_Lapatinib_30min_R1 1 QTIGNSCGTIGLIHAVANNQDK 22 0 P09936;D6RE83;D6R956;D6R974 P09936 UCHL1 Ubiquitin carboxyl-terminal hydrolase isozyme L1;Ubiquitin carboxyl-terminal hydrolase 0 132.67 1.3067e-05 10214000.0 21649.0 27384.0 24659.0 24463.0 21211.0 24535.0 29782.0 24043.0 23569.0 25025.0 False True 21340.281290059615 27320.59403046796 22631.632206492675 26262.090626175734 19963.410682430476 23485.69524387844 31323.966235554828 25160.125553286773 20914.41102742712 29350.53790628352 0.7270831409699982 0.9308379327732532 0.7710806622609657 0.8947737417975363 0.6801718846235048 0.8001793806596811 1.0672365302323412 0.857228771534724 0.7125733468397405 1.0 14.841099323348711 QTLENER ddPTM_PC-9_Lapatinib_30min_R1 1 QTLENER 7 0 P35579 P35579 MYH9 Myosin-9 0 85.161 0.035587 0.0 44010.0 50873.0 35146.0 37726.0 48251.0 36185.0 81023.0 78158.0 49114.0 44150.0 False True 43382.40932955446 50755.20669412781 32256.431547483327 40500.49589024674 45412.971045115904 34637.45190135487 85217.97449141627 81789.50600980672 43582.26412665179 51781.26867382288 0.8378012057376586 0.9801846882864463 0.6229362928643346 0.7821456856409751 0.8770154190539106 0.6689185643469031 1.6457297527454506 1.5795191602007617 0.8416608021171186 1.0 15.660142692161184 -7.247160580064622 24.997408634573617 1.31502070517869 0.7986039702444668 0.47034144498215513 0.24315433992082292 645.2645670670616 1129644.2165388553 0.09247980362389456 0.0712959835709321 5.6602996118022764e-08 7.247160580064622 -0.5164167349342231 QTNGCLNGYT(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 2 QTNGCLNGYTPSR 13 0 A0A2R8Y653;Q9BZX2-2;Q9BZX2 A0A2R8Y653 UCK2 Uridine-cytidine kinase 2 1 QTNGCLNGYT(0.977)PS(0.023)R;QTNGCLNGYT(0.995)PS(0.005)R 112.03 0.00092425 5194400.0 14925.2 11206.7 16162.4 24104.0 21056.0 20490.0 19425.1 23334.5 17837.699999999997 22367.0 True False 19671.10313655447 14829.046616037116 15948.076015675448 18547.19520308768 18132.737853016217 19208.757060879798 21153.89626859501 19728.6891984662 18780.564405613706 21583.938137984936 0.9113769234695811 0.6870408227282636 0.7388862919139347 0.8593054281622043 0.8401033090946896 0.8899560839212596 0.980075838494315 0.9140449287957447 0.8701175978892538 1.0 14.397670498026555 -6.4838545579257225 1.2822256717788856 0.9338907109400448 0.7766703799052053 0.48692319615572277 0.06593473233209046 0.3730578755895624 1.2706585218859716 0.02839376449417002 0.033038069572239155 3.282051882493043e-07 6.4838545579257225 -0.15722033103483957 QTNGCLNGYT(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 1 QTNGCLNGYTPSR 13 0 A0A2R8Y653;Q9BZX2-2;Q9BZX2 A0A2R8Y653 UCK2 Uridine-cytidine kinase 2 1 QTNGCLNGYT(0.992)PS(0.008)R 146.27 1.0558e-07 0.0 10731.0 10425.0 5934.8 7864.2 7644.2 7647.8 7590.8 6912.8 8968.8 7958.7 True False 10577.97397217561 10400.861553010089 5446.863652990498 8442.559502202144 7194.58318507544 7320.721421892546 7983.81448193035 7233.993924417118 7958.639298349041 9334.350690698842 1.1332308290833737 1.1142565667019522 0.5835289280933051 0.9044613580476125 0.7707641831203578 0.7842775212192568 0.8553154629047496 0.7749863021136958 0.8526184157918322 1.0 13.18833395490264 -5.16822508895167 9.400163487218526 0.8096764029793521 1.1265384544384474 0.5935550078434562 0.10186672514221619 0.24426957664850266 23.048888603836758 0.02371033424532035 0.06304802482083512 6.788517017759894e-06 5.16822508895167 0.3168620514590953 QTNGCLNGYTPS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 QTNGCLNGYTPSR 13 0 A0A2R8Y653;Q9BZX2-2;Q9BZX2 A0A2R8Y653 UCK2 Uridine-cytidine kinase 2 1 QTNGCLNGYT(0.392)PS(0.608)R 119.04 0.00023399 3904200.0 12073.0 10601.0 11154.0 9746.7 7942.2 6885.0 8753.8 6782.1 10707.0 7145.4 True False 11900.836806082956 10576.454035823497 10236.961175685117 10463.50483203806 7475.0554109659815 6590.544599718899 9207.028931327643 7097.221125273315 9501.064910291585 8380.472869352978 1.4200674581984263 1.2620354723062377 1.2215254837374674 1.2485578075555424 0.8919610536896947 0.786416793236123 1.098628809478919 0.8468759741741474 1.1337146552954742 1.0 13.03281593515275 -6.205693384671118 5.58085786958818 0.9503246648864634 1.285245503669695 0.6783277292361165 0.11078505402222195 0.12592488332936017 8.661665235009062 0.03264372536065062 0.04205987527136662 6.227397892060814e-07 6.205693384671118 0.33492083878323164 QTNPSAMEVEEDDPVPEIR ddPTM_PC-9_Lapatinib_30min_R1 2 QTNPSAMEVEEDDPVPEIR 19 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 ; 123.29 0.00023362 0.0 3157.69 3467.0 3230.7 3500.6000000000004 3106.09 2081.31 768.24 1768.5700000000002 3149.8 1179.3200000000002 False True 3112.660761550573 3458.972374511845 2965.084316862641 3758.045801659272 2923.3958930078975 1992.297223070578 808.0157081728103 1850.7442186822104 2795.0363551355586 1383.1638906548765 2.25039186070484 2.5007682732912806 2.1436970245505647 2.7169924164807235 2.113557122738202 1.4403912916836628 0.5841792962005717 1.3380512831389433 2.020755728239994 1.0 10.433756395761039 -6.731555974743865 3.361230337755866 1.235953334841894 2.391424449312356 0.6889319996971839 0.36401471108615746 0.1409549072910158 3.302955521741274 0.1331722987820128 0.12640353546792368 1.8554276542399997e-07 6.731555974743865 1.155471114470462 QTPMASS(ph)PRPK ddPTM_PC-9_AZD4547_30min_R2 1 QTPMASSPRPK 11 1 Q5SSJ5;B0QZK4;Q5SWC8;Q5SSJ5-2 Q5SSJ5 HP1BP3 Heterochromatin protein 1-binding protein 3 1 QTPMAS(0.211)S(0.789)PRPK 78.40100000000001 0.008696500000000001 2974500.0 11489.0 16934.0 23691.0 20141.0 15702.0 18035.0 14339.0 17302.0 16651.0 13145.0 True False 15142.263013954536 22407.584337581302 23376.841860575587 15497.803625348048 13522.048336249087 16907.268598973496 15615.14322167629 14628.373460406801 17531.137866309775 12684.797551026604 1.1937331244777372 1.766491285922637 1.8429022431409365 1.2217619999850753 1.0660042686416167 1.332876502834305 1.2310124114209868 1.1532208852022947 1.3820589406955845 1.0 13.630812873767173 -5.801252340726603 14.685340193423986 1.2059512705292852 1.6175558684594626 0.4817645634365987 0.1911469933724666 1.8286039158297678 673.8459534111463 0.053015017104808 0.07869661281457233 1.5803295441070774e-06 5.801252340726603 0.41160459793017745 QTPMASS(ph)PRPK ddPTM_PC-9_Lapatinib_30min_R1 2 QTPMASSPRPK 11 1 Q5SSJ5;B0QZK4;Q5SWC8;Q5SSJ5-2 Q5SSJ5 HP1BP3 Heterochromatin protein 1-binding protein 3 1 QT(0.002)PMAS(0.219)S(0.779)PRPK;QTPMAS(0.189)S(0.811)PRPK 64.798 0.021841 13399400.0 61889.0 54122.0 50355.0 35427.0 45092.0 47393.0 41610.0 43675.0 45704.0 33553.0 True False 61006.451510947394 53996.683834245756 46215.00627592112 38032.41976100756 42439.777214282934 45366.111868478954 43764.36220070633 45704.29994342633 40556.334235543705 39352.59134343781 1.5502524593242688 1.37212523980965 1.1743827966141713 0.9664527407888123 1.0784493667495145 1.152811297039119 1.112108776237024 1.1614050913332723 1.0305886563250841 1.0 15.264171018973055 -5.130542876042629 2.0679410252590618 1.0831171719811332 1.5528225164533984 0.8656452546576986 0.062021458711201065 0.13766672595295257 1.004540593817663 0.01778617098293316 0.09189402663049503 7.403841688701624e-06 5.130542876042629 0.4697053444722652 QTPS(ph)PDVVLR ddPTM_PC-9_AZD4547_30min_R2 2 QTPSPDVVLR 10 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 QT(0.008)PS(0.992)PDVVLR;QT(0.005)PS(0.995)PDVVLR 141.73 0.00012551 183410000.0 120572.0 120605.0 173513.0 226848.0 210144.0 166672.0 146253.0 176239.0 153016.0 161486.0 True False 158911.3879466036 159588.2076906811 171212.10424862 174551.6983666625 180969.13294947948 156249.97349199426 159269.23367039705 149005.31211932906 161104.1133716446 155832.4242925129 1.0197581707919217 1.0241014244321722 1.0986937091297373 1.120124384633917 1.1613060232559975 1.002679475734123 1.0220545203829525 0.9561893989381267 1.03382921816859 1.0 17.249635922849563 -6.874414566815848 14.053547199519963 1.001231021244984 1.0841519479944912 0.4717303001506268 0.04328686527900782 0.6242783857326557 74.65599839340216 0.016683446152535596 0.014713959690032669 1.3353202441550422e-07 6.874414566815848 0.08292092674950724 QTPS(ph)PDVVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 QTPSPDVVLR 10 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 QT(0.109)PS(0.891)PDVVLR;QT(0.002)PS(0.998)PDVVLR;QT(0.204)PS(0.796)PDVVLR;QT(0.271)PS(0.729)PDVVLR;QT(0.026)PS(0.974)PDVVLR 122.52 0.0005319 193772900.0 240466.0 235664.0 279811.0 274918.0 315748.0 246875.0 264526.0 220158.0 229185.0 212759.0 True False 281172.1443800091 259059.16447088186 286482.75542912696 259515.23575618188 253879.4460159829 233928.44040140096 239468.18227760712 214379.0857766827 232536.3970495778 251330.5225006825 1.1187345714416583 1.0307509087766225 1.1398645599375976 1.0325655363067856 1.0101417189203252 0.9307601721982085 0.952801832005728 0.8529767242102501 0.9252214762293598 1.0 17.939226362473512 -6.4620966162041675 1.4425557203665973 0.919783719160278 1.0895765753286277 0.7080954037045004 0.04520150448025302 0.20583995548493858 0.8730382520230493 0.01753054050263783 0.020460329397728138 3.4506696477296114e-07 6.4620966162041675 0.16979285616834972 QTPS(ph)PDVVLR ddPTM_PC-9_Lapatinib_30min_R1 4 QTPSPDVVLR 10 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 QT(0.37)PS(0.63)PDVVLR;QT(0.094)PS(0.906)PDVVLR;QT(0.169)PS(0.831)PDVVLR;QT(0.017)PS(0.983)PDVVLR 127.78 0.0003016 162064220.0 219980.0 236209.8 257238.0 214514.4 255173.2 247375.0 180297.2 226532.0 238371.0 167787.2 True False 216843.04486060856 235662.8707207871 236088.88460739513 230290.5045750613 240164.41406581338 236795.34790929026 189632.10681502515 237057.5037157241 211523.1478220895 196788.99395760937 1.101906364272176 1.1975409090792526 1.1997057348555347 1.1702407738548048 1.2204158842213888 1.2032956881739978 0.9636316696444625 1.2046278551878213 1.0748728552759106 1.0 17.586290010120102 -7.211218188158762 24.999998773032154 1.0778351324238717 1.1848736405264337 0.4356038143186324 0.06653321937950737 374.1445555649779 186248.37900033072 0.024495340465195994 0.01897398536841872 6.148678874395618e-08 7.211218188158762 0.10703850810256199 QTPTPPT(ph)TQLPQQVQPSLPAAPSADQPQQQPR ddPTM_PC-9_AZD4547_30min_R2 1 QTPTPPTTQLPQQVQPSLPAAPSADQPQQQPR 32 0 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 1 QT(0.111)PT(0.287)PPT(0.457)T(0.144)QLPQQVQPSLPAAPSADQPQQQPR 78.025 1.0572e-06 6635700.0 9394.3 10289.0 11724.0 13227.0 15515.0 12000.0 8760.4 16258.0 12110.0 12988.0 True False 12381.491986421193 13614.718037638711 11568.532099674478 10177.719505112882 13361.010058394118 11249.638103004268 9540.058628856466 13745.699671673437 12750.109876945004 12533.294073239531 0.9878880934308836 1.086284097227734 0.9230240694962256 0.8120546318979178 1.066041375899883 0.8975803198477517 0.7611772749532725 1.0967347922540631 1.0172991874632868 1.0 13.613478021547854 QTQS(ph)ASSTLQK ddPTM_PC-9_AZD4547_30min_R2 2 QTQSASSTLQK 11 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1 C9J840 MAP4K4 1 QT(0.342)QS(0.638)AS(0.011)S(0.004)T(0.004)LQK;QT(0.006)QS(0.8)AS(0.146)S(0.038)T(0.01)LQK 151.66 0.00036852 27050900.0 66373.0 65362.0 71060.0 74902.0 81169.0 87151.0 80217.0 85734.0 92937.0 70431.0 True False 87478.23335583652 86488.98827642536 70117.69797022089 57634.50112436422 69900.0854289262 81701.43419291027 87356.15759908002 72485.78027132788 97849.46008535408 67965.23212752781 1.2871026937963683 1.2725475300980384 1.0316701021288983 0.8479997687085166 1.0284682806316015 1.202106306936586 1.285306543721762 1.0665126565788499 1.4396987551186826 1.0 16.05250929849131 -6.8066736026442705 11.418853450249847 1.2083984434985289 1.0864458334834695 0.09348837338555693 0.16159527306227608 1.6470374677218937 410.2323824506429 0.05979909972001743 0.05280765582099764 1.5607250370550634e-07 6.8066736026442705 -0.12195261001505942 QTQS(ph)ASSTLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QTQSASSTLQK 11 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1 C9J840 MAP4K4 1 QT(0.001)QS(0.927)AS(0.02)S(0.041)T(0.011)LQK;QT(0.001)QS(0.994)AS(0.003)S(0.001)T(0.001)LQK;QTQS(0.822)AS(0.049)S(0.096)T(0.033)LQK 130.2 0.00022117 39653000.0 121296.0 170588.0 131855.0 149491.0 161138.0 120045.0 137587.0 101002.0 110418.0 103466.0 True False 141829.01709479792 187522.84926318316 134998.9232628719 141115.50392636145 129564.1656388116 113749.6288728553 124553.76331638168 98350.80452046504 112032.65435966701 122223.56676359446 1.160406465384245 1.5342609795203486 1.104524494232668 1.154568694589873 1.0600587846484253 0.9306685435949559 1.0190650347923025 0.8046795485088055 0.9166207248423803 1.0 16.899162962334074 -6.030969668218281 0.8922775358425111 0.9136335550865486 1.3486735550287838 0.6298116226931701 0.11430718977620931 0.3851624945258143 0.6242789956440752 0.050649482157431994 0.11102588413777904 9.311729077173121e-07 6.030969668218281 0.4350399999422352 QTQS(ph)ASSTLQK ddPTM_PC-9_Lapatinib_30min_R1 3 QTQSASSTLQK 11 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1 C9J840 MAP4K4 1 QT(0.027)QS(0.805)AS(0.025)S(0.048)T(0.095)LQK;QT(0.041)QS(0.948)AS(0.007)S(0.003)T(0.001)LQK;QT(0.001)QS(0.756)AS(0.163)S(0.064)T(0.017)LQK 146.67 0.00023624 44310000.0 144120.0 137759.0 114013.0 109330.0 90694.0 81112.0 65486.0 70048.0 83554.0 59260.0 True False 142064.82237162904 137440.027499388 104639.291242907 117370.49291418858 85359.55723126436 77643.02884130712 68876.54465454102 73302.6858027964 74143.26865737389 69503.01204101348 2.044009578862526 1.977468651549736 1.505536064842193 1.688710884140225 1.228141841980805 1.1171174681680018 0.990986471404969 1.0546691956247989 1.0667633888100017 1.0 16.08478788058664 -5.741188268803518 0.6579915118695367 0.9922125810429128 2.2075874108535993 0.9344711645873456 0.09911629787810128 0.28320258155105515 0.2020320144111533 0.05588222049604104 0.22006137759240044 1.8147287983309805e-06 5.741188268803518 1.2153748298106866 up QTQSASST(ph)LQK ddPTM_PC-9_AZD4547_30min_R2 1 QTQSASSTLQK 11 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1 C9J840 MAP4K4 1 QTQS(0.026)AS(0.143)S(0.143)T(0.687)LQK 124.51 0.0011270999999999998 0.0 31632.0 28550.0 31995.0 34517.0 35805.0 31338.0 33658.0 34303.0 31510.0 31497.0 True False 41690.31801352682 37778.22917432066 31570.725394838377 26559.638932333954 30834.093789287876 29378.42990599564 36653.49679581426 29002.25955452171 33175.55427106003 30394.29961694066 1.3716492414350674 1.2429379735818775 1.0387054741423296 0.8738361885967127 1.0144696268014048 0.9665769659525626 1.2059332591228702 0.9542006205123055 1.0915057984283736 1.0 14.891513154352815 -5.125306952503654 2.7556163965753115 1.0147608508382688 1.3589769006760772 0.6713005654224165 0.08328619510510915 0.16904380516645992 2.355145908254984 0.022538690291581936 0.09020472421573106 7.493643831677091e-06 5.125306952503654 0.3442160498378084 QTQSASST(ph)LQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QTQSASSTLQK 11 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1 C9J840 MAP4K4 1 QTQS(0.025)AS(0.132)S(0.132)T(0.712)LQK 88.021 0.019146 0.0 28549.0 31188.0 22785.0 29184.0 27815.0 30254.0 26256.0 25426.0 22379.0 21192.0 True False 33381.78183154747 34284.13852568857 23328.280812593694 27548.915095804583 22364.850421648207 28667.42698087688 23768.84160302148 24758.594441073863 22706.250538091514 25033.941844220295 1.3334608684191092 1.3695061983857693 0.9318660623947884 1.1004625347152404 0.8933810967852706 1.145142349505596 0.9494646009377506 0.9890010368778578 0.9070185861813773 1.0 14.61159785520842 -5.257151540778336 24.996254318568546 0.9938021548125854 1.3514835754072139 0.7819470700363329 0.07642583196531383 144.88104151640024 844586.661678979 0.018469736765489585 0.045366056775962275 5.5315705938106275e-06 5.257151540778336 0.3576814205946285 QTQSASST(ph)LQK ddPTM_PC-9_Lapatinib_30min_R1 1 QTQSASSTLQK 11 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1 C9J840 MAP4K4 1 QTQS(0.001)AS(0.067)S(0.067)T(0.865)LQK 163.51 0.0037868000000000003 5037900.0 34869.0 27013.0 23042.0 21456.0 27979.0 26941.0 20592.0 19296.0 25921.0 18819.0 True False 34371.76166580855 26950.453058173778 21147.57570469218 23033.945815117797 26333.330228830444 25788.796232538374 21658.153002570172 20192.562603511265 23001.504019769127 22071.83907525872 1.5572676816195778 1.2210334157602531 0.9581247685154344 1.0435897859067642 1.1930736781398799 1.1684026937948344 0.9812572902838774 0.9148563712638692 1.0421199584384662 1.0 14.429919222769884 -4.847165490569814 2.7597589705374 1.043626365621899 1.6154859402168327 0.7840708235883238 0.08331780038846102 0.185841178489325 2.1506502044307862 0.02414569439207875 0.22909146444484177 1.4217869032857704e-05 4.847165490569814 0.5718595745949338 QTQSES(ph)SNYDSELEKEIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QTQSESSNYDSELEKEIK 18 1 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 QT(0.001)QS(0.011)ES(0.367)S(0.296)NY(0.13)DS(0.195)ELEKEIK 46.353 0.045848 5426900.0 7277.2 6338.7 6099.3 12178.0 7930.6 10241.0 7811.4 10528.0 7787.3 5800.8 True False 8509.086228748374 6967.964244991097 6244.730443724061 11495.706141608704 6376.655860288445 9703.94393174985 7071.447642361435 10251.65115533806 7901.174530375804 6852.439120892464 1.2417602080994699 1.0168589785418753 0.9113149834026901 1.6776079201578515 0.9305673130092613 1.416129900689436 1.0319606665021268 1.4960586988772666 1.1530455639198371 1.0 12.742401890438174 QTQSES(ph)SNYDSELEKEIK ddPTM_PC-9_Lapatinib_30min_R1 1 QTQSESSNYDSELEKEIK 18 1 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 QT(0.007)QS(0.02)ES(0.326)S(0.326)NY(0.079)DS(0.243)ELEKEIK 53.358999999999995 0.022993 5010300.0 14577.0 12394.0 11174.0 10932.0 11029.0 10519.0 10501.0 8673.5 10736.0 8746.6 True False 14369.129306905594 12365.302454485083 10255.316852887356 11735.97574808295 10380.295903848273 10069.126890986652 11044.690398212391 9076.50247416848 9526.798624908042 10258.438155888085 1.4007131581388026 1.2053786616033466 0.9996957331171376 1.1440314373145386 1.0118787817510255 0.9815458004401213 1.0766444394727883 0.8847840515526036 0.9286792472828722 1.0 13.32452347732915 -1.5228787452815036 0.5238820185319354 0.9701192292040324 17.049167100054454 0.804775867945615 0.06373872944529692 51.14646687930216 0.5075604862581419 0.034070077290026 915.3493766668993 0.029999999999919456 1.5228787452815036 16.07904787085042 QTQSESSNYDS(ph)ELEK ddPTM_PC-9_AZD4547_30min_R2 1 QTQSESSNYDSELEK 15 0 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 QTQSESSNYDS(1)ELEK 201.18 2.9038999999999997e-10 5918800.0 12494.0 13118.0 10790.0 7227.4 9903.8 12675.0 16274.0 9640.4 13242.0 9986.7 True False 16466.832108655934 17358.136963528486 10646.917549939246 5561.234592216893 8528.828322031819 11882.430246298258 17722.35447308458 8150.697694353577 13941.945085921201 9637.068672714906 1.7086971845783248 1.8011843178698073 1.104787971479698 0.5770670295172039 0.8850023395785475 1.2329921732259277 1.8389777094005004 0.845765239530809 1.4466997755650057 1.0 13.234378670282695 -5.263540848075199 24.29523917108255 1.1133457350918878 1.7549408073781767 0.3764310429742712 0.3287117706122377 127.70977633071723 1476496.9071028067 0.09084773802102061 0.20547742142666015 5.450786252704851e-06 5.263540848075199 0.6415950722862889 QTQSESSNYDS(ph)ELEK ddPTM_PC-9_Lapatinib_30min_R1 2 QTQSESSNYDSELEK 15 0 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 QTQSESSNYDS(1)ELEK;QTQSESSNYDS(1)ELEK 223.65 3.3331e-24 11543600.0 29326.0 37944.0 22914.0 29605.0 38286.0 30906.0 35220.0 32715.0 31738.0 25585.0 True False 28907.805862270263 37856.14299927239 21030.099370597894 31782.25045938489 36034.0927531721 29584.222425404834 37043.519267216456 34235.05833197926 28163.332224043545 30007.333160130434 0.9633580467816757 1.2615630585116562 0.7008320019101119 1.0591494515618176 1.2008428926649566 0.9858997554875096 1.234482220380541 1.1408897334957455 0.938548323296622 1.0 14.873027487635397 -5.987684246002939 24.99909264504559 1.0965115346825982 0.9832337068486924 0.08640369976322737 0.15362460020740581 550.4854393875286 1117390.833360086 0.04236308626710888 0.06278951438871887 1.028763989607004e-06 5.987684246002939 -0.11327782783390583 QTQSESSNYDS(ph)ELEKEIK ddPTM_PC-9_AZD4547_30min_R2 2 QTQSESSNYDSELEKEIK 18 1 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 QTQS(0.004)ES(0.133)S(0.098)NY(0.277)DS(0.487)ELEKEIK;QT(0.002)QS(0.011)ES(0.032)S(0.119)NY(0.068)DS(0.768)ELEKEIK 49.662 0.035054 16082900.0 37978.0 37057.6 39374.0 47843.0 50281.0 48975.0 35689.0 38233.0 31306.5 44646.0 True False 50054.214008526855 49035.74449913503 38851.87503348541 36813.53551698159 43300.35106323653 45912.58550788616 38865.2518612459 32324.968356937505 32961.29767651354 43082.95712918479 1.1618100832410057 1.1381703524226698 0.9017922079254582 0.8544802392880261 1.005045938081731 1.0656786016386175 0.9021026979347763 0.750295952527369 0.7650658142540836 1.0 15.39482965657163 -7.49132531025933 4.885202060604328 0.8183247218537819 1.0117203716302698 0.36332306028298855 0.10905858528284523 0.21745597454929094 13.212582574443337 0.05275119026908556 0.033046613051024354 3.226076708989107e-08 7.49132531025933 0.19339564977648793 QTQSESSNYDS(ph)ELEKEIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QTQSESSNYDSELEKEIK 18 1 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 QT(0.001)QS(0.026)ES(0.205)S(0.205)NY(0.132)DS(0.431)ELEKEIK 47.058 0.043549000000000004 5821700.0 11910.0 11821.0 11906.0 14976.0 15323.0 13155.0 15332.0 16716.0 14625.0 12309.0 True False 13926.127766777496 12994.51075773261 12189.884193756447 14136.943272847095 12320.568147075866 12465.128641946032 13879.641965932553 16277.222712066023 14838.862957218304 14540.524262009614 0.9577459186366913 0.8936755321597096 0.8383386990801465 0.9722443990402075 0.8473262672698891 0.8572681711700025 0.954548936189064 1.1194385029564529 1.0205177399268999 1.0 13.82779166645249 -7.557849691232783 5.74025790642211 1.0515025612360482 0.8939995549028236 0.6482759767703512 0.05010881026641948 0.10558769223405595 9.408711853971518 0.023242099685647857 0.01343375702577331 2.7678994461291963e-08 7.557849691232783 -0.15750300633322467 QTQSESSNYDS(ph)ELEKEIK ddPTM_PC-9_Lapatinib_30min_R1 2 QTQSESSNYDSELEKEIK 18 1 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 QT(0.001)QS(0.009)ES(0.049)S(0.014)NY(0.002)DS(0.925)ELEKEIK;QT(0.001)QS(0.004)ES(0.014)S(0.014)NY(0.051)DS(0.916)ELEKEIK 57.922 0.015562000000000001 13562900.0 59718.0 47653.0 50956.0 52269.0 40167.0 52973.0 43331.0 42037.4 43847.0 33659.5 True False 58866.41036906005 47542.66240629158 46766.59437584818 56113.036624272514 37804.45603136038 50707.46827609429 45574.46715978869 43990.61106907366 38908.48913062064 39477.49972653548 1.4911382629810261 1.2042977071907863 1.1846392172707232 1.4213928696845806 0.9576203227974304 1.2844650402723046 1.1544415800262808 1.1143211037629268 0.9855864581126861 1.0 15.268743000388517 -1.5228787452916757 0.16645067741133732 0.9626148945679273 2.6676973962711066 0.4822988250255309 0.12278600247576431 56.56144702003625 0.6029854969327668 0.3270632144673783 23.87688517070264 0.029999999999216792 1.5228787452916757 1.7050825017031794 QTS(ph)LVSSR ddPTM_PC-9_AZD4547_30min_R2 1 QTSLVSSR 8 0 G3V3A4;Q13573;G3V5R3 G3V3A4 SNW1 SNW domain-containing protein 1 1 QT(0.083)S(0.863)LVS(0.053)SR 80.87100000000001 0.018686 6072600.0 24574.0 29351.0 42587.0 75210.0 48472.0 33559.0 29737.0 48598.0 36696.0 36744.0 True False 32388.020829046814 38838.136759911926 42022.2685541485 57871.4964829167 41742.499487623565 31460.55042489335 32383.53539179775 41088.29577094263 38635.67564363121 35457.60374400317 0.913429487871822 1.0953401431274241 1.1851412424127952 1.6321321909043083 1.177251000631517 0.88727232251881 0.9133029864510986 1.1588006924436272 1.0896301939232298 1.0 15.11380742048271 -6.590249124308647 8.810174353941315 1.0149766363961021 1.2227161548334682 0.21323540541031472 0.18277574424262166 0.49837494894759743 59.630717219887856 0.06572710216090738 0.06571696368135485 2.5689217496583526e-07 6.590249124308647 0.20773951843736604 QTSIQSPSSYGNS(ph)SPPLNK ddPTM_PC-9_AZD4547_30min_R2 1 QTSIQSPSSYGNSSPPLNK 19 0 Q9H3D4-8;Q9H3D4-4;Q9H3D4-10;Q9H3D4-7;Q9H3D4-3;Q9H3D4-12;Q9H3D4-2;Q9H3D4-9;Q9H3D4-11;Q9H3D4 Q9H3D4-8 TP63 Tumor protein 63 1 QTSIQSPSSYGNS(0.989)S(0.011)PPLNK 290.18 1.3638999999999997e-227 0.0 15512.0 14738.0 23117.0 29520.0 24736.0 21527.0 19385.0 24587.0 19478.0 18131.0 True False 20444.493330356232 19501.77028270185 22810.453475620518 22714.620079453547 21301.83337444004 20180.913286947754 21110.227446279016 20787.64410305294 20507.56731487489 17496.2392086469 1.1685078768385986 1.1146264091464746 1.3037346599803719 1.298257288813681 1.2175092670150713 1.1534429225781302 1.2065580033820085 1.1881207072648718 1.1721128792489157 1.0 14.094757229714844 -9.481231005477387 0.5970522962318322 0.9872404141108303 1.2149924527375795 0.5584302153875822 0.05519580250035224 3.357280970439578 1.4391346789490473 0.1621740549145952 0.02537089371674075 3.3019386097779113e-10 9.481231005477387 0.2277520386267492 QTSIQSPSSYGNS(ph)SPPLNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QTSIQSPSSYGNSSPPLNK 19 0 Q9H3D4-8;Q9H3D4-4;Q9H3D4-10;Q9H3D4-7;Q9H3D4-3;Q9H3D4-12;Q9H3D4-2;Q9H3D4-9;Q9H3D4-11;Q9H3D4 Q9H3D4-8 TP63 Tumor protein 63 1 QTSIQS(0.001)PSSYGNS(0.736)S(0.263)PPLNK 153.32 2.4045e-05 3795400.0 17910.0 16445.0 14749.0 20374.0 20827.0 18046.0 22004.0 16317.0 19113.0 15764.0 True False 20941.80926137572 18077.550918781224 15100.67209589399 19232.510833399218 16746.098857870464 17099.63599183262 19919.621824835645 15888.696039290577 19392.491466756466 18621.888412244658 1.124580321703873 0.9707689423643249 0.8109098154602128 1.0327905745989248 0.8992696383498472 0.9182546696278614 1.0696886042844975 0.8532268955517479 1.0413815740623333 1.0 14.184711760976631 QTVAVGVIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QTVAVGVIK 9 0 Q5VTE0;P68104;A0A087WVQ9;A0A2U3TZH3;Q05639 Q5VTE0 EEF1A1P5;EEF1A1;EEF1A2 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 2 0 ; 130.66 0.0058 32819000.0 247210.0 241548.0 242630.0 297110.0 300240.0 258330.0 264350.0 239980.0 229353.0 211866.0 False True 289057.7703799383 265527.28910488146 248415.21937939918 280463.8899436168 241410.12729087382 244782.72003602586 239308.8542717374 233680.77927982813 232706.8537317534 250275.6286696668 1.1549577236761601 1.060939455097104 0.9925665583174975 1.1206200597094287 0.9645770488084785 0.9780525628370675 0.9561812132638604 0.9336937061029549 0.9298022942493452 1.0 17.93315828560177 -4.535549627813689 0.41046683539939066 0.9435680154238976 1.3102496851368517 0.6308997683889379 0.04484075956860574 4.467437669750129 0.508379277340695 0.03583130124447204 0.8386746809420927 2.913737156404516e-05 4.535549627813689 0.36668166971295413 QTVAVGVIK ddPTM_PC-9_Lapatinib_30min_R1 2 QTVAVGVIK 9 0 Q5VTE0;P68104;A0A087WVQ9;A0A2U3TZH3;Q05639 Q5VTE0 EEF1A1P5;EEF1A1;EEF1A2 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 2 0 ; 117.31 0.0085963 116061000.0 709530.0 711550.0 768900.0 726080.0 825680.0 680410.0 805900.0 611160.0 746960.0 742990.0 False True 699411.9720881343 709902.4496925023 705684.0100398326 779478.3453318769 777115.1257493377 651310.4504131784 847625.5587010153 639556.7247492726 662829.4989624913 871414.8315280575 0.8026165573308983 0.8146550001308362 0.80981409141544 0.8944974507319704 0.8917855166484121 0.7474172195016259 0.9727004040253403 0.7339291249241038 0.7606360082260658 1.0 19.7330001426473 -11.908879587509679 2.3965125377239116 2.4482380591227826 0.8279103804016456 0.35188988233320495 0.07103411050862805 8275506.576529711 982388.8556814456 66841618.44220048 0.017397711060738074 1.233446771282094e-12 11.908879587509679 -1.6203276787211371 QTVPSENIPLPECS(ph)SPPSCK ddPTM_PC-9_AZD4547_30min_R2 1 QTVPSENIPLPECSSPPSCK 20 0 A0A494C142;Q99728-3;Q99728-2;Q99728 A0A494C142 BARD1 BRCA1-associated RING domain protein 1 1 QTVPSENIPLPECS(0.499)S(0.499)PPS(0.003)CK 72.654 0.015501 0.0 26910.0 26240.0 24536.0 28240.0 34634.0 26066.0 28170.0 29558.0 25950.0 30040.0 True False 35466.82023722836 34721.56684883272 24210.636608462395 21729.70430365069 29825.66692635656 24436.08889940911 30677.075427478987 24990.490275269003 27321.664022025005 28988.308743464375 1.2234870461432013 1.197778289037333 0.835186240864116 0.7496023481725133 1.028886065423909 0.8429635932078448 1.0582568199807572 0.8620885922123102 0.9425063139699336 1.0 14.823183544663399 -5.25030479396137 23.693855107071357 0.910723835837295 1.2106328032514817 0.6255363021482105 0.09146695008728514 219.56157817927536 467211.06834763597 0.02300470923682032 0.059505525955210234 5.619468046138527e-06 5.25030479396137 0.2999089674141867 QTVPSENIPLPECS(ph)SPPSCKR ddPTM_PC-9_Lapatinib_30min_R1 1 QTVPSENIPLPECSSPPSCKR 21 1 A0A494C142;Q99728-3;Q99728-2;Q99728 A0A494C142 BARD1 BRCA1-associated RING domain protein 1 1 QTVPSENIPLPECS(0.82)S(0.129)PPS(0.051)CKR 136.34 3.6661e-05 5367700.0 43737.0 37489.0 43320.0 37821.0 38763.0 39227.0 32222.0 28623.0 37947.0 28254.0 True False 43113.3023596165 37402.196523817285 39758.396820035814 40602.482507157445 36483.03655099018 37549.35265260324 33890.29749654314 29952.929073398805 33673.00926037494 33137.66625391148 1.3010361692120527 1.1286913277848114 1.1997947144314318 1.2252668065411771 1.1009537084309258 1.133132078912498 1.0227122585176869 0.9038937396462928 1.016155120953947 1.0 15.016184382758677 -7.030608156818103 1.177026896624049 0.9651771336648352 1.20491062671775 0.7639084764045426 0.05526139745873892 0.22104368385494758 0.6242473462886892 0.03183737762830289 0.022283093087601936 9.319483487640053e-08 7.030608156818103 0.23973349305291491 QTVPSENIPLPECSS(ph)PPSCKR ddPTM_PC-9_AZD4547_30min_R2 1 QTVPSENIPLPECSSPPSCKR 21 1 A0A494C142;Q99728-3;Q99728-2;Q99728 A0A494C142 BARD1 BRCA1-associated RING domain protein 1 1 QTVPSENIPLPECS(0.242)S(0.758)PPS(0.001)CKR 120.8 8.5949e-07 6230600.0 16937.0 10621.0 16882.0 31151.0 25075.0 19501.0 15487.0 21782.0 13978.0 18819.0 True False 22322.61368851492 14054.030545024865 16658.13364949715 23969.61822815235 21593.769076005967 18281.599387223865 16865.312997705605 18416.092400565303 14716.848543347423 18160.152538057788 1.2292084904977514 0.7738938599536638 0.9172904035132473 1.3199018112826866 1.189074212386291 1.0066875456531306 0.9286988621026933 1.0140934863829556 0.8103923418322442 1.0 14.148488700293656 -6.998705166772069 24.919075307349004 0.9435024115167774 1.074747712389388 0.16709627361503698 0.15441747650645896 92.86303859606657 1787108.3496308436 0.05860650080188015 0.051293914626149066 1.002985912671805e-07 6.998705166772069 0.13124530087261066 QTVPSENIPLPECSS(ph)PPSCKR ddPTM_PC-9_Lapatinib_30min_R1 1 QTVPSENIPLPECSSPPSCKR 21 1 A0A494C142;Q99728-3;Q99728-2;Q99728 A0A494C142 BARD1 BRCA1-associated RING domain protein 1 1 QTVPSENIPLPECS(0.088)S(0.912)PPSCKR 138.24 5.0403999999999994e-05 4107300.0 37723.0 28246.0 40405.0 36348.0 39324.0 35055.0 31532.0 31323.0 37129.0 27355.0 True False 37185.063102449036 28180.59812242907 37083.05686781038 39021.15317337348 37011.039633958644 33555.779367196235 33164.57267273908 32778.38093023341 32947.141034296816 32083.275301753663 1.1590170502453816 0.8783578938677974 1.1558376293888994 1.2162459351910555 1.1535929323255731 1.045896313627371 1.0337028361604437 1.021665669166943 1.026925733872811 1.0 14.969533810007935 -6.930391072978043 6.450028123227222 1.0247047851950002 1.107594611339897 0.21024249349209678 0.08495032671443256 0.40675725454868294 29.436088295625897 0.03234844606618405 0.028447141010329788 1.1738400607849506e-07 6.930391072978043 0.0828898261448967 QTY(ph)DDGAAT(ph)RLMS(ph)TVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QTYDDGAATRLMSTVK 16 1 Q6PJT7;Q6PJT7-2;Q6PJT7-9;Q6PJT7-5;H0YJA2;Q6PJT7-11;Q6PJT7-3;Q6PJT7-4;G3V256;G3V3Y4;G3V572;G3V3R9;A0A3B3IT62 Q6PJT7 ZC3H14 Zinc finger CCCH domain-containing protein 14 3 QT(0.371)Y(0.682)DDGAAT(0.947)RLMS(0.979)T(0.022)VK 50.07899999999999 0.032629000000000005 4210600.0 11213.0 8314.7 10262.0 11800.0 12564.0 11758.0 11316.0 8713.5 9454.8 7968.8 True False 13111.139433155004 9140.128466062042 10506.684998851726 11138.884256116165 10102.174391428654 11141.389781223976 10244.066559254677 8484.779857716396 9593.058563275736 9413.48035901391 1.3928046729922146 0.9709616547199655 1.116131823528055 1.1832907523358338 1.073160404669595 1.1835569158600834 1.088233699818095 0.9013435556373967 1.0190767067453292 1.0 13.200512500535522 -7.586730810174038 5.6928324606992495 0.9716525904845933 1.1407788727954689 0.3680420816888377 0.10453807681873406 0.21941838877595038 13.682762217636519 0.0475529149758942 0.02710636970446204 2.589817670872692e-08 7.586730810174038 0.16912628231087556 QTYSTEPNNLK ddPTM_PC-9_Lapatinib_30min_R1 2 QTYSTEPNNLK 11 0 P46779;H0YKD8;P46779-2;P46779-3;H0YLP6;H0YMF4;P46779-4;P46779-5 P46779 RPL28 60S ribosomal protein L28 0 ; 158.08 0.0020589000000000002 13409900.0 30759.0 35179.0 34777.0 35559.0 35271.0 33906.0 31864.0 30755.0 32990.0 33781.0 False True 30320.37101949022 35097.54518689132 31917.769303102166 38174.12748134663 33196.42912545402 32455.9194187464 33513.762008250575 32183.989576647436 29274.318799899065 39620.000839646884 0.7652794138547638 0.8858542262263145 0.8055973908804853 0.9635064783528878 0.8378704801095075 0.8191801799829459 0.845879891418732 0.8123167313121712 0.7388772887305162 1.0 15.273941290351164 -6.501904747569933 24.868761735406743 0.8313338472110957 0.8595963097642345 0.0 0.07811260937692968 3398.4353991074354 4029509.1466766666 0.023327555686587034 0.02615318442589289 3.1484387754622414e-07 6.501904747569933 0.0282624625531388 QVAAS(ph)PAVGQPLQK ddPTM_PC-9_Lapatinib_30min_R1 1 QVAASPAVGQPLQK 14 0 Q92547;A0A2R8YD63 Q92547 TOPBP1 DNA topoisomerase 2-binding protein 1 1 QVAAS(1)PAVGQPLQK 130.01 2.0809e-05 3793600.0 10601.0 17027.0 17479.0 10802.0 14246.0 13373.0 13017.0 11726.0 13556.0 10450.0 True False 10449.827796014692 16987.575027635758 16041.944090891171 11596.415114415662 13408.078288713625 12801.067963985599 13690.956567329837 12270.832767867598 12029.180528991565 12256.268576250257 0.8526108685529281 1.386031557806562 1.30887667735812 0.9461619613074379 1.0939771925931276 1.0444506730858554 1.117057486310284 1.001188305521108 0.9814716815443539 1.0 13.5812321965936 -5.765243977327731 24.999855695273148 1.033733150893951 1.2028588856068028 0.2063493730848015 0.1381122610009287 137.52972184453287 903711.7287589869 0.037774031424897415 0.058520451330696666 1.7169435740923337e-06 5.765243977327731 0.16912573471285186 QVAEQGGDLS(ph)PAANR ddPTM_PC-9_AZD4547_30min_R2 4 QVAEQGGDLSPAANR 15 0 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 QVAEQGGDLS(1)PAANR;QVAEQGGDLS(1)PAANR;QVAEQGGDLS(1)PAANR;QVAEQGGDLS(1)PAANR 189.59 1.9578e-07 233924000.0 77294.59999999999 83297.2 127123.0 189233.0 150228.0 138671.0 119575.0 156162.0 104980.0 134141.0 True False 101872.67497244415 110221.39093447367 125437.2659593075 145608.25547070595 129371.4353240367 129999.88044847548 130216.94335253126 132030.751145766 110529.02847908219 129444.7644193426 0.7869972604100285 0.8514936191424949 0.9690408609570904 1.1248678625502453 0.9994335105352864 1.0042884394098364 1.0059653160686142 1.0199775304781427 0.8538702123248341 1.0 16.981977088967987 -5.211212498937335 2.982477598972365 1.004805911979836 0.8005626220450587 0.5794369235294092 0.06187444426533843 0.18246469842132063 3.1710235353962397 0.01669813233899569 0.05428287062101725 6.148759422102728e-06 5.211212498937335 -0.20424328993477736 QVAEQGGDLS(ph)PAANR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 QVAEQGGDLSPAANR 15 0 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 QVAEQGGDLS(1)PAANR;QVAEQGGDLS(1)PAANR;QVAEQGGDLS(1)PAANR;QVAEQGGDLS(1)PAANR;QVAEQGGDLS(1)PAANR;QVAEQGGDLS(1)PAANR 155.26 6.9152e-12 210951000.0 62361.9 77068.0 109841.0 91921.0 116428.0 100352.0 104014.0 98810.0 89911.0 80356.0 True False 72918.53796633102 84718.80171533176 112460.02601431214 86770.96438190299 93614.76918539115 95089.36446040041 94161.04092385249 96216.34219784877 91225.77828009933 94923.90670225417 0.7681788550386265 0.8924917300450713 1.1847387019906708 0.9141107587794047 0.9862085583880428 1.0017430567693049 0.9919633967363506 1.013615489927617 0.9610411270392117 1.0 16.534483857072303 -5.0070091553603016 10.546110662449708 1.0048485288054703 0.7988254700868593 0.5618265514611933 0.06639001079607536 0.1265489183364397 189.48246338605398 0.016021990317303843 0.051239687650677816 9.839903620454502e-06 5.0070091553603016 -0.20602305871861093 QVAEQGGDLS(ph)PAANR ddPTM_PC-9_Lapatinib_30min_R1 4 QVAEQGGDLSPAANR 15 0 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 QVAEQGGDLS(1)PAANR;QVAEQGGDLS(1)PAANR;QVAEQGGDLS(1)PAANR;QVAEQGGDLS(1)PAANR 167.29 0.00013744 222991900.0 123041.0 93891.0 110226.0 100125.0 99637.0 90261.0 80115.0 73917.0 92377.0 70091.0 True False 121286.41277704379 93673.60115814566 101163.64376466435 107488.52650720856 93776.54755387885 86400.74743866769 84262.96269429433 77351.45366727508 81972.52948706511 82206.13595961295 1.4753936717890572 1.1394964629424567 1.2306094013999762 1.3075487036638798 1.1407487587051937 1.051025527840349 1.0250203553624255 0.9409450129766114 0.9971582842348581 1.0 16.326958461876394 -6.6512881987517325 1.357485094512747 0.9807772442039457 1.281710777347119 0.7323945495550647 0.0815784091468605 0.22350881642214582 0.8604280880459397 0.03601714947179546 0.03587023713190713 2.2320905111901562e-07 6.6512881987517325 0.3009335331431733 QVAGDAPVEQATAET(ph)ASPVHR ddPTM_PC-9_AZD4547_30min_R2 2 QVAGDAPVEQATAETASPVHR 21 0 Q92766;Q92766-2;A0A087X055;Q92766-4 Q92766 RREB1 Ras-responsive element-binding protein 1 1 QVAGDAPVEQAT(0.001)AET(0.638)AS(0.361)PVHR;QVAGDAPVEQATAET(0.926)AS(0.074)PVHR 209.29 1.6947e-24 57180000.0 81201.0 101756.0 133185.0 113517.0 113843.0 113009.0 115974.0 170449.0 107004.0 101451.0 True False 107021.22891427642 134646.63705296573 131418.87987846683 87347.40947016704 98037.86452322008 105942.52936520087 126295.4613285922 144110.0235783657 112660.01298700432 97899.23136928094 1.0931774174057285 1.3753594912821294 1.3423892919317013 0.8922175204899017 1.001416080106045 1.0821589493954267 1.290055698723509 1.4720240553756267 1.1507752554465411 1.0 16.5790099124726 -7.269858216348851 24.10541902600398 1.2675491005843262 1.1350699375566198 0.05013186296869643 0.1759689761531571 969.6416426783528 2776329.8751092204 0.07732016702986227 0.05315070316081735 5.372071491837249e-08 7.269858216348851 -0.13247916302770646 QVAGDAPVEQATAET(ph)ASPVHR ddPTM_PC-9_Lapatinib_30min_R1 1 QVAGDAPVEQATAETASPVHR 21 0 Q92766;Q92766-2;A0A087X055;Q92766-4 Q92766 RREB1 Ras-responsive element-binding protein 1 1 QVAGDAPVEQATAET(0.763)AS(0.236)PVHR 161.04 8.9642e-06 26525000.0 32215.0 60816.0 69798.0 46520.0 55535.0 72047.0 53835.0 74844.0 71030.0 57192.0 True False 31755.60819249253 60675.184288523895 64059.47786807153 49941.23598617078 52268.54048601089 68965.71775975997 56622.31288332194 78321.52547145511 63029.853420940584 67077.56099645021 0.47341626202200554 0.9045526311210819 0.9550060693390686 0.7445296943461273 0.7792254177037978 1.028148858355325 0.8441319577245575 1.1676263165799952 0.9396563095708886 1.0 16.03354261164942 -3.8008078568454593 0.3664724535082397 1.0092762946112288 1.6578271956816145e-23 0.4647929684991242 0.13165108446558152 13.114386364833264 0.8020488956489561 0.11575513128616034 6.724832635330724 0.0001581947779237629 3.8008078568454593 -1.0092762946112288 QVAGDAPVEQATAETAS(ph)PVHR ddPTM_PC-9_AZD4547_30min_R2 1 QVAGDAPVEQATAETASPVHR 21 0 Q92766;Q92766-2;A0A087X055;Q92766-4 Q92766 RREB1 Ras-responsive element-binding protein 1 1 QVAGDAPVEQATAET(0.088)AS(0.912)PVHR 184.88 5.4354e-15 6261600.0 20580.0 26252.0 26921.0 24853.0 26567.0 28675.0 27408.0 37327.0 25087.0 27263.0 True False 27124.011909407633 34737.44561415992 26564.00995013107 19123.524825022323 22878.63062980062 26881.947716970615 29847.258903668586 31558.96983912867 26413.04760387442 26308.53066821136 1.0309968371658864 1.320387141807704 1.0097108913128472 0.7268944459953938 0.8696278373860273 1.021795859905324 1.1345087751226288 1.1995717372867738 1.0039727393742042 1.0 14.68324305576594 -9.716240428648867 15.726031551839908 0.9999940514579636 1.036320455437855 0.004556171219195937 0.1557274677586363 0.0 0.0 0.16791569932991557 0.04072553909039404 1.9220273856956266e-10 9.716240428648867 0.036326403979891286 QVAGDAPVEQATAETAS(ph)PVHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QVAGDAPVEQATAETASPVHR 21 0 Q92766;Q92766-2;A0A087X055;Q92766-4 Q92766 RREB1 Ras-responsive element-binding protein 1 1 QVAGDAPVEQATAET(0.003)AS(0.997)PVHR;QVAGDAPVEQATAET(0.114)AS(0.886)PVHR 240.8 6.721499999999999e-52 50503000.0 97133.0 104894.0 104899.0 88864.0 123145.0 77946.0 98655.0 71600.0 79804.0 71790.0 True False 113575.69843580174 115307.18309970437 107400.18999167264 83885.23818097508 99015.62125377909 73858.37454390922 89309.68419965297 69720.57586647097 80970.98252566489 84804.95871067258 1.3392577528784104 1.3596750101971706 1.2664376190322522 0.9891548732092978 1.16756876908093 0.870920470533927 1.0531186567090856 0.8221285279359111 0.9547906603187204 1.0 16.371861003985813 -5.738098850703472 0.853653637308077 0.9359058199925778 1.415080873828775 0.7524201345560895 0.09026156512208135 0.37630410292774924 0.48893938766521927 0.03776292315027984 0.13114915902359855 1.8276841656615812e-06 5.738098850703472 0.4791750538361972 QVAGDAPVEQATAETAS(ph)PVHR ddPTM_PC-9_Lapatinib_30min_R1 1 QVAGDAPVEQATAETASPVHR 21 0 Q92766;Q92766-2;A0A087X055;Q92766-4 Q92766 RREB1 Ras-responsive element-binding protein 1 1 QVAGDAPVEQATAET(0.173)AS(0.827)PVHR 239.14 1.2643e-51 24868000.0 47608.0 63677.0 62173.0 43375.0 54335.0 74338.0 55009.0 63320.0 60123.0 51690.0 True False 46929.10118976205 63529.55981880323 57061.375934720345 46564.942194758296 51139.12212672014 71158.73703034178 57857.096858895835 66262.07836102472 53351.31461674238 60624.54762740437 0.7740940431949465 1.0479180844243643 0.9412255953713154 0.768087252064036 0.8435382056954683 1.173761121776612 0.9543509869052194 1.092990891548888 0.8800282510087672 1.0 15.887614456571459 -6.722301588098758 24.99892263456885 1.021921434409857 0.8823232936326931 0.3220358071468086 0.10509286758741017 204.42339229444048 130573.07814804424 0.034527588419893625 0.034527129010587965 1.8953892446551698e-07 6.722301588098758 -0.13959814077716393 QVDAESWK ddPTM_PC-9_AZD4547_30min_R2 1 QVDAESWK 8 0 P26639;P26639-2;D6RCA5;D6R9F8;D6RDJ6;D6RBR8 P26639 TARS Threonine--tRNA ligase, cytoplasmic 0 93.111 0.032057 0.0 17278.0 16106.0 20988.0 28491.0 27359.0 23305.0 17892.0 25565.0 14956.0 17993.0 False True 22772.044595274285 21311.949530003807 20709.685406684417 21922.84013156203 23560.675100715755 21847.734665876207 19484.353338603265 21614.51667525718 15746.543626720842 17363.070546642957 1.3115217457707744 1.2274297609258025 1.192743262261784 1.2626130886625162 1.3569417366256722 1.258287502039801 1.122172100047733 1.2448556617444726 0.9068985571659351 1.0 14.083734481173735 -8.255795726928065 24.861599877696598 0.9534492645350501 1.2449960765233143 0.7755858520379979 0.06316893465841547 181.39787602517805 799109.1445889437 0.04786062388360167 0.0169688757956866 5.5488664592294226e-09 8.255795726928065 0.29154681198826427 QVDAESWK ddPTM_PC-9_Lapatinib_30min_R1 1 QVDAESWK 8 0 P26639;P26639-2;D6RCA5;D6R9F8;D6RDJ6;D6RBR8 P26639 TARS Threonine--tRNA ligase, cytoplasmic 0 94.309 0.031206 4467300.0 47139.0 31453.0 39182.0 39311.0 35450.0 40967.0 41567.0 32322.0 35448.0 31466.0 False True 46466.78921576614 31380.172510966575 35960.60720689388 42202.062077651746 33364.9006973816 39214.93690874135 43719.135871106955 33823.79811726221 31455.47295601158 36904.85617419052 1.2590968786450054 0.8502992766819765 0.9744139643075752 1.1435368255727232 0.9040788708103787 1.062595576139012 1.1846445265835235 0.916513478811955 0.8523396706260578 1.0 15.171523047256711 -7.941291804601688 24.999949514270174 0.9122526879777122 1.0418602645341264 0.18820512101969722 0.12241922097532876 121.15020265065209 51589.30157175072 0.0651700241567994 0.0313066599873981 1.1447435241740541e-08 7.941291804601688 0.1296075765564142 QVDLES(ph)NPQNRSPESRPSVVYPSTK ddPTM_PC-9_Lapatinib_30min_R1 1 QVDLESNPQNRSPESRPSVVYPSTK 25 2 J3QS41;P42694 J3QS41 HELZ Probable helicase with zinc finger domain 1 QVDLES(0.618)NPQNRS(0.336)PES(0.018)RPS(0.021)VVY(0.005)PS(0.001)TK 49.106 0.0095916 15696000.0 20051.0 21005.0 26700.0 22753.0 24710.0 19711.0 17635.0 18148.0 30386.0 20226.0 True False 19765.069063096933 20956.36421304335 24504.829064980502 24426.33152178295 23256.606381729154 18868.006478585205 18548.054011282296 18991.222332531222 26963.60870123471 23722.037150549066 0.8331944232976406 0.8834133459974916 1.0329985114458569 1.0296894557058556 0.9803798145215729 0.7953788436820018 0.7818912808191512 0.8005729951439544 1.1366481103673094 1.0 14.53394028744336 -6.71587580129805 24.99916618611128 0.8828705208463654 0.9569515946185045 0.02791975718728179 0.11622970317023426 357.0490909017232 195899.3341025611 0.039787681601458035 0.039787527382998844 1.923641769635887e-07 6.71587580129805 0.07408107377213913 QVDLESNPQNRS(ph)PESRPSVVYPSTK ddPTM_PC-9_Lapatinib_30min_R1 1 QVDLESNPQNRSPESRPSVVYPSTK 25 2 J3QS41;P42694 J3QS41 HELZ Probable helicase with zinc finger domain 1 QVDLES(0.008)NPQNRS(0.989)PES(0.002)RPS(0.001)VVYPSTK 57.04600000000001 0.0016753 14021000.0 23381.0 26307.0 32359.0 29603.0 28930.0 26565.0 14658.0 19964.0 26960.0 15931.0 True False 23047.582652449717 26246.087757797268 29698.567929352233 31780.103372713078 27228.394278568383 25428.876876039565 15416.919517855173 20891.600322165174 23923.480898614085 18684.652123276846 1.2335034391000326 1.4046869904043107 1.589463252160555 1.7008667414857708 1.4572598996717723 1.3609499769257647 0.8251114024568422 1.1181155626729047 1.280381392212855 1.0 14.189566082968648 -7.058665434909339 5.6076270018767325 1.0657468562784114 1.485187058513386 0.6239722156855125 0.15479272324447801 0.15360816646245723 10.158581942305165 0.06347456253500228 0.049669976222622404 8.736441337227677e-08 7.058665434909339 0.4194402022349746 QVDQLTNDK ddPTM_PC-9_Lapatinib_30min_R1 2 QVDQLTNDK 9 0 P08670;B0YJC4 P08670 VIM Vimentin 0 ; 137.46 0.0043482 10790800.0 70029.0 75451.0 76640.0 69717.0 70518.0 54788.0 72388.0 59571.0 56929.0 73015.0 False True 69030.37361825412 75276.29784519559 70338.95503895533 74844.22074909431 66370.26988372231 52444.84495706595 76135.89644279584 62338.88613462737 50517.05653105347 85635.54546362803 0.8060948668514452 0.8790309845946818 0.8213756876089542 0.8739854501292676 0.7750317876110422 0.6124191149029445 0.8890688560526893 0.7279557314328611 0.5899075700114454 1.0 16.38592213201416 -6.405897982123116 5.649880873234823 0.7486111367551782 0.8450814589336334 0.09601309390512724 0.11457739944578867 0.47068415099990324 20.08746171463939 0.03449379463369813 0.03906370793826825 3.927371804302992e-07 6.405897982123116 0.09647032217845519 QVEDDIQQLLK ddPTM_PC-9_Lapatinib_30min_R1 2 QVEDDIQQLLK 11 0 P35998;C9JLS9 P35998 PSMC2 26S protease regulatory subunit 7 0 ; 174.4 2.2948e-12 1785400.0 17861.2 17850.300000000003 23673.0 21215.5 20959.1 15920.1 20224.8 18412.2 20288.3 15930.7 False True 17606.496012657077 17808.968727069176 21726.697320422605 22775.758642833312 19726.32694517604 15239.234434565704 21271.941183293573 19267.69802904074 18003.218008729684 18684.300268676565 0.942314978858139 0.9531514946227424 1.1628317361633547 1.2189784105009223 1.0557701739704102 0.8156170804059295 1.1384927922056078 1.031223955512116 0.9635478851146122 1.0 14.189538915020153 -6.542004716889395 24.976396979627133 0.9937638609370276 1.0764101747652 0.11195281054784467 0.1077063155914559 581.0229013037281 758746.6074166805 0.037993447133267126 0.03799873705461387 2.870749402533556e-07 6.542004716889395 0.08264631382817234 QVEEALHQLHAR ddPTM_PC-9_AZD4547_30min_R2 1 QVEEALHQLHAR 12 0 F5H169;F5H5V4;F5GX23;J3KN29;O00233-2;O00233 F5H169 PSMD9 26S proteasome non-ATPase regulatory subunit 9 0 93.839 0.0021449999999999998 1511200.0 6828.9 7424.5 9885.5 10119.0 9336.2 9336.2 9049.9 10270.0 7995.9 9669.7 False True 9000.348150056057 9824.324430989273 9754.411810929041 7786.220886991546 8040.029784542646 8752.405938105701 9855.32356802066 8683.00748112228 8418.546950046624 9331.166746227611 0.9645469205332445 1.052850591804185 1.0453582147026297 0.8344316524125288 0.8616317769471922 0.9379755154031633 1.056172699089849 0.9305382399936891 0.9021966040259715 1.0 13.187841768071047 -5.721462633457055 24.999735866632406 0.9314647197960743 1.0241118806525151 0.2922637512486804 0.06345584418084613 207.44308856118036 129724.44424195636 0.018493191692630875 0.032030643824619225 1.8990542290236363e-06 5.721462633457055 0.09264716085644087 QVEEEILALK ddPTM_PC-9_Lapatinib_30min_R1 2 QVEEEILALK 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 162.36 0.00064694 4531000.0 23418.0 19012.0 21412.0 20615.0 17826.6 20718.8 20622.0 18323.0 19604.9 20807.0 False True 23084.055025664766 18967.9788820938 19651.58801271022 22131.095869624038 16778.07443644407 19832.705221881748 21689.70625577906 19174.353471400143 17396.789713250713 24403.462226415224 0.9459336061207626 0.7772658939173864 0.805278686703668 0.9068834440085517 0.687528444971339 0.812700470034702 0.8887962722068719 0.7857226689188841 0.7128820309119817 1.0 14.574798223343189 -12.064953279411052 2.18822507112569 3.8749743773875704 0.8127397208820293 0.342092451192038 0.07751236392868141 3014263.5994163956 249799.94015315975 43104143.24383129 0.018944790311909727 8.61086381266164e-13 12.064953279411052 -3.062234656505541 QVETEEAGVVTTATAS(ph)VNLKVSPK ddPTM_PC-9_AZD4547_30min_R2 2 QVETEEAGVVTTATASVNLKVSPK 24 1 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 QVETEEAGVVT(0.008)T(0.061)AT(0.082)AS(0.425)VNLKVS(0.425)PK;QVETEEAGVVT(0.037)T(0.133)AT(0.142)AS(0.488)VNLKVS(0.2)PK 67.641 0.00049649 2137700.0 29793.0 30003.0 26788.3 30095.0 27830.0 28668.0 23847.9 25776.1 24931.0 25379.0 True False 39266.55426710308 39700.88300935705 26433.069638835714 23157.06271311499 23966.284880767555 26875.385428077214 25970.316900496135 21792.996020852584 26248.801762354728 24490.48893476638 1.603338927683097 1.6210735161354084 1.0793198008109863 0.9455533033577587 0.9785956068335299 1.0973805177864482 1.060424598695088 0.8898554895698929 1.0717957421051023 1.0 14.579933956094113 -5.291905898621511 4.4215954001653905 1.0076040341162478 1.6210322373036037 0.9421732887786495 0.05931193720468805 0.03907202567048008 1.8640613161638009 0.01592207279415928 0.03789322700977912 5.1061562636161375e-06 5.291905898621511 0.6134282031873559 QVETEEAGVVTTATAS(ph)VNLKVSPK ddPTM_PC-9_Lapatinib_30min_R1 1 QVETEEAGVVTTATASVNLKVSPK 24 1 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 QVETEEAGVVT(0.02)T(0.019)AT(0.016)AS(0.472)VNLKVS(0.472)PK 45.327 0.024836 1477200.0 3028.4 3710.1 2258.4 2476.9 2135.9 2161.0 2103.7 3115.7 2560.8 2587.8 True False 2985.2144606594575 3701.509491397864 2072.7230696761044 2659.0594886961812 2010.2705613409685 2068.5790675370436 2212.6192925168466 3260.4667964220603 2272.375737580526 3035.097781973245 0.9835645093182611 1.2195684479698563 0.6829180535753743 0.8761034008490541 0.6623412837902068 0.6815526932355283 0.7290108759126467 1.074254284585946 0.7486993503395989 1.0 11.567527281306287 -3.0657089891474296 11.61102696267176 0.858325853925644 1.0479233168084787 0.0 0.18502987782694555 0.0 0.0 0.043968401673507844 0.0 0.0008595893198176124 3.0657089891474296 0.18959746288283474 QVETEEAGVVTTATASVNLKVS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 6 QVETEEAGVVTTATASVNLKVSPK 24 1 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 QVETEEAGVVTTATAS(0.001)VNLKVS(0.999)PK;QVETEEAGVVTTAT(0.001)AS(0.015)VNLKVS(0.985)PK;QVETEEAGVVT(0.012)T(0.028)AT(0.034)AS(0.028)VNLKVS(0.897)PK;QVETEEAGVVTTATAS(0.001)VNLKVS(0.998)PK;QVETEEAGVVT(0.262)T(0.262)AT(0.003)AS(0.039)VNLKVS(0.433)PK;QVETEEAGVVTTAT(0.002)AS(0.006)VNLKVS(0.992)PK 108.31 4.7033e-07 37805400.0 124355.40000000001 122336.00000000001 116644.6 138530.9 136280.1 151161.0 121667.8 118057.59999999999 124978.7 131098.8 True False 163897.83044699457 161878.71958913098 115097.81638977224 106594.74128606942 117359.96048075777 141708.87877401916 132495.99849824 99814.51061376285 131584.81893292704 126509.07091536932 1.2955421240634768 1.2795819178643946 0.909798922377425 0.8425857570116694 0.9276802021514171 1.1201479684315923 1.0473240973121662 0.7889909386856195 1.0401216132632358 1.0 16.94888130675121 -5.255585828512246 24.250963017949672 0.955595620332943 1.2875620995570372 0.6611649805322242 0.09388307046131779 186.3882600065884 772187.6499347981 0.02537372946796314 0.06332696714941512 5.551548924302858e-06 5.255585828512246 0.33196647922409417 QVETEEAGVVTTATASVNLKVS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 11 QVETEEAGVVTTATASVNLKVSPK 24 1 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 QVETEEAGVVT(0.079)T(0.062)AT(0.216)AS(0.201)VNLKVS(0.442)PK;QVETEEAGVVT(0.001)T(0.004)AT(0.026)AS(0.128)VNLKVS(0.841)PK;QVETEEAGVVT(0.006)T(0.006)AT(0.071)AS(0.055)VNLKVS(0.862)PK;QVETEEAGVVT(0.001)T(0.002)AT(0.002)AS(0.386)VNLKVS(0.609)PK;QVETEEAGVVT(0.001)T(0.002)AT(0.002)AS(0.011)VNLKVS(0.984)PK;QVETEEAGVVT(0.025)T(0.025)AT(0.087)AS(0.388)VNLKVS(0.475)PK;QVETEEAGVVT(0.002)T(0.007)AT(0.03)AS(0.072)VNLKVS(0.888)PK;QVETEEAGVVT(0.016)T(0.016)AT(0.253)AS(0.154)VNLKVS(0.561)PK;QVETEEAGVVT(0.186)T(0.186)AT(0.186)AS(0.205)VNLKVS(0.236)PK;QVETEEAGVVTTAT(0.012)AS(0.03)VNLKVS(0.958)PK;QVETEEAGVVTT(0.001)AT(0.001)AS(0.008)VNLKVS(0.989)PK 89.751 0.0003621 32745300.0 102568.57 94645.5 74817.69999999998 108889.29999999997 104792.20000000001 106193.1 97420.5 114069.6 101541.6 88217.1 True False 119931.40307940074 104041.2797496815 76601.63771570737 102788.58554487379 84258.92066710205 100624.14689373151 88192.12497665882 111075.39386673189 103026.45380216626 104210.16190382066 1.1508609226621276 0.9983794080053823 0.7350687909534754 0.9863585629944718 0.8085480257181413 0.9655886245201422 0.8462910273381451 1.0658787189031278 0.9886411451625333 1.0 16.66913644124157 -7.7723914640833565 24.992115677254006 1.020444943970311 0.9218165143888141 0.12364992942203279 0.1101395412689948 454.32192618013755 1036723.7871988838 0.0597707750315696 0.02915321687216006 1.6889178895959394e-08 7.7723914640833565 -0.09862842958149687 QVETEEAGVVTTATASVNLKVS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 13 QVETEEAGVVTTATASVNLKVSPK 24 1 O75475-3;O75475-2;O75475 O75475-3 PSIP1 PC4 and SFRS1-interacting protein 1 QVETEEAGVVT(0.052)T(0.052)AT(0.339)AS(0.095)VNLKVS(0.46)PK;QVETEEAGVVT(0.011)T(0.024)AT(0.066)AS(0.138)VNLKVS(0.761)PK;QVETEEAGVVT(0.009)T(0.033)AT(0.004)AS(0.003)VNLKVS(0.951)PK;QVETEEAGVVT(0.002)T(0.007)AT(0.006)AS(0.026)VNLKVS(0.958)PK;QVETEEAGVVT(0.001)T(0.002)AT(0.018)AS(0.061)VNLKVS(0.918)PK;QVETEEAGVVTTATASVNLKVS(0.999)PK;QVETEEAGVVTTATASVNLKVS(0.999)PK;QVETEEAGVVT(0.001)T(0.009)AT(0.026)AS(0.124)VNLKVS(0.84)PK;QVETEEAGVVT(0.001)T(0.004)AT(0.003)AS(0.007)VNLKVS(0.984)PK;QVETEEAGVVTTATASVNLKVS(1)PK;QVETEEAGVVTT(0.001)AT(0.002)AS(0.061)VNLKVS(0.936)PK;QVETEEAGVVT(0.018)T(0.064)AT(0.059)AS(0.197)VNLKVS(0.662)PK;QVETEEAGVVT(0.144)T(0.144)AT(0.004)AS(0.036)VNLKVS(0.673)PK 96.12299999999999 2.6838e-06 76947900.0 124505.29999999999 103848.4 81299.36 96201.4 95767.5 97030.2 94215.3 98403.29999999999 101419.2 80301.0 True False 122729.83159052418 103607.94541022665 74615.2404454052 103276.37187446283 90134.64393614932 92880.44453444364 99093.3072349966 102975.47655690838 89996.30170447787 94180.92085564318 1.3031283881651534 1.1000948437214033 0.7922543097637844 1.0965742417486106 0.9570371909434201 0.9861917221727651 1.0521590395881022 1.0933793768564353 0.9555682922491346 1.0 16.523147208232494 -4.865602762187367 3.8930533267431224 0.9967027973738266 1.3081691566903328 0.564717511599262 0.0830683812613612 0.16177326641717485 4.085628039956115 0.020457449947511478 0.11883005325377824 1.362690530021895e-05 4.865602762187367 0.31146635931650624 QVHPDTGIS(ph)SK ddPTM_PC-9_AZD4547_30min_R2 6 QVHPDTGISSK 11 0 Q16778;P33778;P23527;P06899;Q96A08;Q8N257;U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 Q16778;Q8N257;U3KQK0 HIST2H2BE;HIST1H2BB;HIST1H2BO;HIST1H2BJ;HIST1H2BA;HIST3H2BB;HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B type 2-E;Histone H2B type 1-B;Histone H2B type 1-O;Histone H2B type 1-J;Histone H2B type 1-A;Histone H2B type 3-B;Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 1 QVHPDTGIS(0.816)S(0.184)K;QVHPDTGIS(0.677)S(0.323)K;QVHPDTGIS(0.664)S(0.336)K;QVHPDT(0.001)GIS(0.5)S(0.5)K;QVHPDTGIS(0.5)S(0.5)K;QVHPDTGIS(0.931)S(0.069)K 162.46 3.1565e-05 53500400.0 436478.0 560581.0 544892.0 740928.0 647356.0 618199.0 458953.0 591028.0 493205.0 528377.0 True False 575268.9246936054 741777.8454910625 537666.376053892 570118.4968234883 557481.793577943 579542.9188032621 499798.9278902295 499698.20307232096 519274.80940203706 509878.6820554418 1.1282466691381567 1.4548124320490912 1.0544986385514912 1.1181453880856629 1.0933616430689 1.1366290437305346 0.9802310735475772 0.9800335269125572 1.018428162771421 1.0 18.95979449481979 -5.814354716234065 0.5586028034138621 0.9920373052601346 1.3203172286016143 0.45207474711868834 0.09812834871462278 1.3021423488370893 0.6631783929584711 0.06539782649445373 0.2448702477221664 1.5333640741491143e-06 5.814354716234065 0.3282799233414797 QVHPDTGIS(ph)SK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QVHPDTGISSK 11 0 Q16778;P33778;P23527;P06899;Q96A08;Q8N257;U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 Q16778;Q8N257;U3KQK0 HIST2H2BE;HIST1H2BB;HIST1H2BO;HIST1H2BJ;HIST1H2BA;HIST3H2BB;HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B type 2-E;Histone H2B type 1-B;Histone H2B type 1-O;Histone H2B type 1-J;Histone H2B type 1-A;Histone H2B type 3-B;Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 1 QVHPDTGIS(0.722)S(0.278)K;QVHPDTGIS(0.576)S(0.424)K;QVHPDT(0.077)GIS(0.618)S(0.305)K;QVHPDT(0.029)GIS(0.486)S(0.486)K 153.0 5.9041000000000006e-05 18078500.0 344268.0 389998.0 322477.0 445304.0 427957.0 389233.0 475821.0 347693.0 345790.0 330671.0 True False 402545.77279705735 428714.42403301 330166.0746808321 420355.06057504617 344101.89796502946 368820.93627446453 430747.7902342807 338566.4271611851 350846.524579591 390619.03470980516 1.0305329157758856 1.0975256859960916 0.8452380589341116 1.0761253887367066 0.8809143113588058 0.9441960158149112 1.1027311829652326 0.8667432896932674 0.8981808191713915 1.0 18.575402727328544 -5.232315459512248 24.98643002017724 0.9540391745296997 1.0640293190305372 0.22480116792064664 0.08330265695774863 1059.88474729608 909309.1318454657 0.02053531735125738 0.054313871174740826 5.857125645368662e-06 5.232315459512248 0.10999014450083755 QVHPDTGIS(ph)SK ddPTM_PC-9_Lapatinib_30min_R1 4 QVHPDTGISSK 11 0 Q16778;P33778;P23527;P06899;Q96A08;Q8N257;U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 Q16778;Q8N257;U3KQK0 HIST2H2BE;HIST1H2BB;HIST1H2BO;HIST1H2BJ;HIST1H2BA;HIST3H2BB;HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B type 2-E;Histone H2B type 1-B;Histone H2B type 1-O;Histone H2B type 1-J;Histone H2B type 1-A;Histone H2B type 3-B;Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 1 QVHPDTGIS(0.5)S(0.5)K;QVHPDT(0.001)GIS(0.711)S(0.288)K;QVHPDT(0.002)GIS(0.85)S(0.148)K;QVHPDT(0.002)GIS(0.499)S(0.499)K 157.5 0.00049426 16864900.0 184488.0 193177.0 156388.0 137281.0 168783.0 160087.0 196521.0 204228.0 139396.0 138312.0 True False 181857.16728904456 192729.71052525993 143530.38231513763 147377.102695991 158855.51578014533 153240.45219102368 206695.8957953621 213717.1784509691 123695.75457504496 162219.04491084476 1.1210592898570748 1.1880831293957115 0.884793659055394 0.9085067833865569 0.9792655102084468 0.9446514265648913 1.2741777385569106 1.317460465683469 0.7625230110498301 1.0 17.307583679845834 -7.210057857325749 24.99952433130323 1.114996373227111 1.0018058425963223 0.048300210914011044 0.16699820281818273 901.9409525147768 438836.96111056086 0.06525991464660047 0.050550062390070365 6.165128636737694e-08 7.210057857325749 -0.11319053063078877 QVHPDTGISS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QVHPDTGISSK 11 0 Q16778;P33778;P23527;P06899;Q96A08;Q8N257;U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 Q16778;Q8N257;U3KQK0 HIST2H2BE;HIST1H2BB;HIST1H2BO;HIST1H2BJ;HIST1H2BA;HIST3H2BB;HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B type 2-E;Histone H2B type 1-B;Histone H2B type 1-O;Histone H2B type 1-J;Histone H2B type 1-A;Histone H2B type 3-B;Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 1 QVHPDTGIS(0.409)S(0.591)K 127.07 0.00021469 8210600.0 85632.0 104600.0 86230.0 109520.0 114330.0 98985.0 118960.0 83622.0 85106.0 82095.0 True False 100127.80629090584 114983.99672268287 88286.05022909596 103383.94946863047 91927.85722477222 93794.05234686646 107691.24760418345 81427.01110483291 86350.51424526641 96978.1736363375 1.0324777476876321 1.185668820222024 0.9103703123979577 1.066053789137278 0.9479231643348568 0.9671666193528112 1.11046891858388 0.8396426541314282 0.8904118422468525 1.0 16.565372463654803 -5.242661458894423 0.4585541742165837 0.9391821888526806 1.1635397453846414 0.2053146567156091 0.08976413375669016 5.103957521679011 1.136395847681065 0.0678635803697535 0.5951400047380933 5.719242892039329e-06 5.242661458894423 0.22435755653196088 QVHPDTGISSK ddPTM_PC-9_AZD4547_30min_R2 5 QVHPDTGISSK 11 0 Q16778;P33778;P23527;P06899;Q96A08;Q8N257;U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 Q16778;Q8N257;U3KQK0 HIST2H2BE;HIST1H2BB;HIST1H2BO;HIST1H2BJ;HIST1H2BA;HIST3H2BB;HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B type 2-E;Histone H2B type 1-B;Histone H2B type 1-O;Histone H2B type 1-J;Histone H2B type 1-A;Histone H2B type 3-B;Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 0 ;;;; 194.17 0.00069122 181178300.0 385828.0 390805.0 764980.0 1072090.0 897148.0 780753.0 635349.0 950586.0 689896.0 786176.0 False True 508513.27827905427 517125.07364169473 754835.8653709475 824936.214125385 772594.4861017187 731932.3914862409 691893.8301658963 803694.7759931955 726362.4941094009 758652.2175333488 0.6702851010340598 0.6816365413430865 0.9949695630300671 1.0873707280623912 1.0183776811642378 0.9647798748496594 0.9120039646301858 1.0593718141446897 0.9574380425210732 1.0 19.533079149237636 -5.260715210113641 6.613541967922448 1.001317611813681 0.673846686404803 0.882293886754658 0.04724632467295746 0.04042051915295855 10.58468639932673 0.012896879629728065 0.030709587470569753 5.486366170649423e-06 5.260715210113641 -0.327470925408878 QVHPDTGISSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QVHPDTGISSK 11 0 Q16778;P33778;P23527;P06899;Q96A08;Q8N257;U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 Q16778;Q8N257;U3KQK0 HIST2H2BE;HIST1H2BB;HIST1H2BO;HIST1H2BJ;HIST1H2BA;HIST3H2BB;HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B type 2-E;Histone H2B type 1-B;Histone H2B type 1-O;Histone H2B type 1-J;Histone H2B type 1-A;Histone H2B type 3-B;Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 0 ;; 117.03 0.0010093 156736700.0 232661.0 248834.0 331882.0 391748.0 421240.0 363496.0 371711.0 312659.0 308390.0 276378.0 False True 272045.91203578707 273536.59503338486 339795.32554949395 369799.6296241521 338701.04589664214 344433.6298618634 336499.84312540723 304452.03253959346 312899.6203334402 326483.14359295514 0.833261739157235 0.8378276195919575 1.040774484740737 1.1326760259488375 1.0374227660553272 1.0549813569894075 1.030680602441578 0.9325199126334403 0.9583944116990913 1.0 18.316648981422517 -5.2583755135985415 24.142704938902373 1.0268081949812888 0.8355446395209691 0.6792842737166582 0.051598718175342215 98.83810732310036 778808.22857385 0.015029654154014417 0.03632633608872904 5.516002907243363e-06 5.2583755135985415 -0.1912635554603197 QVHPDTGISSK ddPTM_PC-9_Lapatinib_30min_R1 5 QVHPDTGISSK 11 0 Q16778;P33778;P23527;P06899;Q96A08;Q8N257;U3KQK0;Q99879;Q99877;Q93079;Q5QNW6;P62807;P58876;Q5QNW6-2;Q99880;O60814;P57053 Q16778;Q8N257;U3KQK0 HIST2H2BE;HIST1H2BB;HIST1H2BO;HIST1H2BJ;HIST1H2BA;HIST3H2BB;HIST1H2BN;HIST1H2BM;HIST1H2BH;HIST2H2BF;HIST1H2BC;HIST1H2BD;HIST1H2BL;HIST1H2BK;H2BFS Histone H2B type 2-E;Histone H2B type 1-B;Histone H2B type 1-O;Histone H2B type 1-J;Histone H2B type 1-A;Histone H2B type 3-B;Histone H2B;Histone H2B type 1-M;Histone H2B type 1-N;Histone H2B type 1-H;Histone H2B type 2-F;Histone H2B type 1-C/E/F/G/I;Histone H2B type 1-D;Histone H2B type 1-L;Histone H2B type 1-K;Histone H2B type F-S 0 ;;;; 134.13 0.00026988 405926300.0 645345.0 599353.0 715026.0 672386.0 703727.0 735725.0 672835.0 586604.0 699721.0 598795.0 False True 636142.2619582206 597965.2349526383 656239.3223601795 721835.509453941 662335.1614405153 704259.7568087413 707671.1040930602 613859.7633431873 620911.052591215 702295.9179058147 0.9058037299364369 0.8514434153849542 0.9344199583517843 1.02782244784562 0.9430998309310142 1.0027963125697534 1.0076537340602432 0.8740756534277796 0.8841159926469709 1.0 19.42171952396906 -5.4633014329463805 6.208870264143291 0.9617909686317723 0.8808522294644735 0.3052277115229244 0.05019006018570714 0.2897501547618069 23.12511010647793 0.014112951565707152 0.02937660240850604 3.4411100900649026e-06 5.4633014329463805 -0.08093873916729877 QVHQCIER ddPTM_PC-9_AZD4547_30min_R2 2 QVHQCIER 8 0 E7EQY1;C9JF51;Q96C01 E7EQY1 FAM136A Protein FAM136A 0 ; 87.639 0.009714200000000001 2125600.0 13073.5 12065.7 16174.9 23820.0 18894.9 15423.4 16921.7 18236.699999999997 15491.2 16017.199999999999 False True 17230.601054307124 15965.701567376558 15960.410257508085 18328.667015331434 16271.669284714866 14458.972359823005 18427.698518323436 15418.637052676031 16310.033206088387 15456.442703256242 1.114784390245054 1.0329479993487136 1.0326056625012217 1.1858269957206968 1.0527434803149678 0.935465723738419 1.1922341299425405 0.9975540522935302 1.055225546991632 1.0 13.915920701082516 -6.505391832569496 24.97400452717658 1.0399686523564609 1.087663702982675 0.11092811816768011 0.07357422226734536 1963.058081216741 2803553.5244732792 0.022893550772757603 0.025416873116889595 3.123260203264581e-07 6.505391832569496 0.04769505062621415 QVHQCIER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QVHQCIER 8 0 E7EQY1;C9JF51;Q96C01 E7EQY1 FAM136A Protein FAM136A 0 69.954 0.033118 646330.0 4150.6 5561.2 5234.6 5730.9 6916.9 5953.9 5333.7 5701.0 4955.5 4955.0 False True 4853.214601913241 6113.279183309589 5359.412716331047 5409.816252828488 5561.583098382111 5641.667002758077 4828.45332335602 5551.354790708804 5027.964812615063 5853.302276241585 0.8291412903127049 1.0444154247975956 0.9156220648444513 0.9242331930791964 0.9501616072275038 0.9638434402503813 0.8249109810977296 0.9484141649819832 0.8589962683156571 1.0 12.515035068912649 QVHQCIER ddPTM_PC-9_Lapatinib_30min_R1 2 QVHQCIER 8 0 E7EQY1;C9JF51;Q96C01 E7EQY1 FAM136A Protein FAM136A 0 ; 116.37 0.0030156999999999996 2652000.0 23191.0 20791.2 18542.9 20669.8 18988.5 21698.0 20644.6 16914.5 22609.0 19929.1 False True 22860.292087291455 20743.059253807518 17018.374339663933 22189.926044431475 17871.63376282736 20770.02712050845 21713.47637319639 17700.40941941809 20062.536336675286 23373.81838114345 0.9780298500878968 0.887448465439508 0.728095600905041 0.9493496390958927 0.7646005231753272 0.8886022292902054 0.9289657350428238 0.7572750472681727 0.8583337137957955 1.0 14.512605813693973 -8.620468471138068 19.48111086270295 1.0000000003630665 0.8565554101125779 0.2111962963774756 0.08087376422750621 45547.37740457193 9092266.985114 0.07563533524334874 0.01952895952452574 2.3962467058798025e-09 8.620468471138068 -0.1434445902504886 QVLEPSFR ddPTM_PC-9_Lapatinib_30min_R1 1 QVLEPSFR 8 0 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 0 104.06 0.017804 3714500.0 46992.0 29663.0 35733.0 27082.0 40035.0 31569.0 28119.0 31869.0 33457.0 33263.0 False True 46321.88546272262 29594.317145989302 32795.17067336887 29073.700622903605 37680.220011838406 30218.867460933325 29574.864232676326 33349.7500835044 29688.720342171062 39012.46522983851 1.187361147003177 0.7585861844832666 0.840633127903069 0.7452413081721048 0.9658507810221348 0.7745951783077927 0.7580875512080206 0.8548485692208189 0.7610060058307665 1.0 15.25164754588139 -4.75530455555784 24.998728994831485 0.8223688254085632 1.1873617459239858 0.6101097886787773 0.08586334388476069 126.76333638016202 516496.72148882353 0.019772582526394404 0.17757400763123907 1.7566912756501997e-05 4.75530455555784 0.36499292051542265 QVLQSTQS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 QVLQSTQSPR 10 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 QVLQS(0.316)T(0.148)QS(0.536)PR;QVLQSTQS(0.999)PR;QVLQS(0.001)T(0.004)QS(0.995)PR 160.18 0.00012844 233854000.0 101268.0 92718.0 122781.0 157145.0 126816.0 108380.0 99050.0 133386.0 94802.0 101984.0 True False 133469.11749474707 122687.28030068862 121152.84371631981 120917.64811604781 109209.78740350035 101602.98146696677 107865.25811472462 112774.25860535342 99813.04017788106 98413.57120151391 1.3562064242283476 1.2466500179072997 1.2310583005695874 1.2286684309875722 1.1097025142993728 1.0324082362474394 1.0960404830128276 1.1459218198111543 1.0142202844514356 1.0 16.58656965603962 -1.5228787452803385 0.22761847675173794 1.002835311039832 2.9791613427081645 0.8491158333643424 0.04321703892895903 19.986416365177515 0.26021141537679005 0.0689521757749222 14.66675077120944 0.029999999999999933 1.5228787452803385 1.9763260316683324 QVLQSTQS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QVLQSTQSPR 10 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 QVLQS(0.008)T(0.004)QS(0.988)PR;QVLQS(0.315)T(0.037)QS(0.648)PR;QVLQSTQS(0.999)PR;QVLQS(0.003)T(0.001)QS(0.996)PR 133.88 0.00011042 126272000.0 54389.7 46895.9 58335.6 66090.0 100503.0 103026.0 124851.0 96390.0 104543.0 83371.0 True False 63596.80196445823 51551.41502779402 59726.54194299499 62387.191566670925 80810.15861682214 97623.13519309253 113024.20943703635 93859.86463364713 106071.74359907489 98485.50233552726 0.6457478558396568 0.5234416620241736 0.6064500919080907 0.6334657394966206 0.8205284706932039 0.9912437148414316 1.1476228151020402 0.9530322982349099 1.0770290152727484 1.0 16.58762374627051 -6.499832003603648 1.8259480970219748 1.045230167461006 0.5862287779906441 0.9307553053304329 0.055671534009662536 0.07946481197238366 0.5332670596437121 0.020528677580339147 0.022722880432537805 3.1635011480031616e-07 6.499832003603648 -0.45900138947036195 QVLQSTQS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 QVLQSTQSPR 10 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 QVLQS(0.045)T(0.012)QS(0.942)PR;QVLQS(0.012)T(0.006)QS(0.982)PR;QVLQS(0.009)T(0.003)QS(0.988)PR;QVLQS(0.011)T(0.005)QS(0.984)PR 148.13 0.00015022 186690000.0 83591.0 89331.0 86175.0 90545.0 126767.0 165823.0 169194.0 169644.0 184889.0 145859.0 True False 82398.97701128811 89124.15955798022 79090.0241451197 97203.98134926564 119310.81429351118 158731.13684229285 177954.03744739995 177526.2795558702 164064.85385251694 171070.53380509923 0.4816666855389913 0.5209790229538854 0.4623240623965494 0.568209961044549 0.6974363827580153 0.9278695361010292 1.0402378100377188 1.0377373332927458 0.9590480032022122 1.0 17.384231757383972 -6.602864976239237 1.6333819811688068 1.01658539997634 0.49444811119048376 0.9831103103347987 0.03031360483203173 0.042823702218768356 0.23469758694829496 0.012556354591757407 0.012942641466822622 2.4953704262480423e-07 6.602864976239237 -0.5221372887858562 down QVPGGGGGGGS(ph)GGGGGSGGGGSGGGR ddPTM_PC-9_Lapatinib_30min_R1 1 QVPGGGGGGGSGGGGGSGGGGSGGGR 26 0 Q9UHB9-4;Q9UHB9-2;Q9UHB9;K7EN53;K7EQC2 Q9UHB9-4 SRP68 Signal recognition particle subunit SRP68 1 QVPGGGGGGGS(0.423)GGGGGS(0.289)GGGGS(0.289)GGGR 49.515 0.024649 1547000.0 3026.1 3140.5 1202.8 2350.4 1203.1 3217.0 2420.9 1845.5 1227.1 620.02 True False 2982.9472590812234 3133.228365201745 1103.9104269422678 2523.2562567045507 1132.3360233856067 3079.4164091932753 2546.242356445327 1931.248667328984 1088.8910760641456 727.1896308752807 4.102021168110997 4.308681301506512 1.5180502857467146 3.4698738122371697 1.55713994714511 4.234681406948474 3.5014833110045123 2.6557703593826543 1.4973963184176644 1.0 9.50618781781133 -5.236294969244938 24.313554749660668 2.59721909744902 4.205352056121393 0.31900694592496703 1.0145134407563785 687.0628319436685 664356.1221714106 0.2527596986821864 0.6680594258670625 5.803701010225867e-06 5.236294969244938 1.6081329586723734 QVPGGGGGGGSGGGGGS(ph)GGGGSGGGR ddPTM_PC-9_AZD4547_30min_R2 2 QVPGGGGGGGSGGGGGSGGGGSGGGR 26 0 Q9UHB9-4;Q9UHB9-2;Q9UHB9;K7EN53;K7EQC2 Q9UHB9-4 SRP68 Signal recognition particle subunit SRP68 1 QVPGGGGGGGS(0.086)GGGGGS(0.685)GGGGS(0.229)GGGR;QVPGGGGGGGS(0.082)GGGGGS(0.459)GGGGS(0.459)GGGR 170.55 1.6185999999999998e-13 3149800.0 3250.1 4932.1 6061.799999999999 6384.9 5714.4 6888.5 7180.2 5840.1 2265.1 5782.5 True False 4283.5641937203945 6526.3048725277395 5981.416571290237 4912.95995072165 4921.054197723971 6457.761006045406 7819.223890109498 4937.646737147251 2384.828561706701 5580.056435056018 0.7676560700729529 1.1695768579555992 1.0719276123647645 0.8804498678286806 0.8819004350579778 1.1572931351509848 1.4012804316791827 0.8848739783574755 0.42738430864682814 1.0 12.446063997785318 -8.002331730094385 24.98967277478566 0.6945044304049235 1.0513412742220545 0.2841832955826066 0.21240497396117414 98.40082753655255 1054574.6601424965 0.11823190576231261 0.05529376188200088 9.946453804015078e-09 8.002331730094385 0.356836843817131 QVPGGGGGGGSGGGGGS(ph)GGGGSGGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QVPGGGGGGGSGGGGGSGGGGSGGGR 26 0 Q9UHB9-4;Q9UHB9-2;Q9UHB9;K7EN53;K7EQC2 Q9UHB9-4 SRP68 Signal recognition particle subunit SRP68 1 QVPGGGGGGGS(0.051)GGGGGS(0.474)GGGGS(0.474)GGGR 56.461000000000006 0.004324100000000001 2080900.0 1303.2 2157.5 2497.6 2417.7 2757.6 2835.4 2492.2 1986.2 2262.6 2233.3 True False 1523.8060206267367 2371.682341579233 2557.152256200747 2282.244107289157 2217.2680755972347 2686.706632563572 2256.1207740345094 1934.0643545528553 2295.686244581343 2638.179611206929 0.577597527535139 0.8989844101229416 0.9692866419473566 0.8650829145954407 0.8404537985883631 1.0183941309949107 0.8551808847474061 0.7331056408506048 0.8701781466391895 1.0 11.365327073427641 -4.7602723392795845 24.992547584513044 0.8885470088174862 0.5775971547145259 0.5831539365558358 0.0802409692753663 22.056352281158233 472141.4397725506 0.02058979354396604 0.1233143957735825 1.7367114226299455e-05 4.7602723392795845 -0.3109498541029603 QVPGGGGGGGSGGGGGSGGGGS(ph)GGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QVPGGGGGGGSGGGGGSGGGGSGGGR 26 0 Q9UHB9-4;Q9UHB9-2;Q9UHB9;K7EN53;K7EQC2 Q9UHB9-4 SRP68 Signal recognition particle subunit SRP68 1 QVPGGGGGGGS(0.088)GGGGGS(0.049)GGGGS(0.863)GGGR 148.72 1.6064999999999998e-09 1619400.0 2948.0 2833.1 2633.6 2923.0 3295.8 1045.0 2979.1 1026.9 2224.7 3883.9 True False 3447.038174345933 3114.351444694378 2696.3950119836204 2759.2337864938613 2650.011649098261 990.198360382638 2696.898081183777 999.9449630904876 2257.232028781099 4588.020325064518 0.7513127514964659 0.6788007079394495 0.587703371158388 0.601399643201245 0.5775937030228818 0.21582257492913648 0.5878130195828747 0.21794693402462773 0.4919838773271688 1.0 12.1636560672113 -11.073243277877994 2.8315576069438055 1.025671435931858 0.5175944015803723 0.4194256715259693 0.1681046222438251 47061861.2962563 49280081.604361355 9202501.836165786 0.04508482480278411 8.448054795817071e-12 11.073243277877994 -0.5080770343514857 QVPGGGGGGGSGGGGGSGGGGS(ph)GGGR ddPTM_PC-9_Lapatinib_30min_R1 1 QVPGGGGGGGSGGGGGSGGGGSGGGR 26 0 Q9UHB9-4;Q9UHB9-2;Q9UHB9;K7EN53;K7EQC2 Q9UHB9-4 SRP68 Signal recognition particle subunit SRP68 1 QVPGGGGGGGS(0.057)GGGGGS(0.164)GGGGS(0.779)GGGR 133.91 5.7528e-10 1233400.0 2278.7 931.38 2060.7 2031.2 964.85 1120.3 868.75 1010.5 2111.5 1159.7 True False 2246.205320137597 929.223446833817 1891.2772005320346 2180.5812238845674 908.0994199680855 1072.3873805468525 913.7296241736034 1057.4515190116163 1873.6806349192752 1360.1525997968838 1.6514362583088327 0.6831758781864484 1.3904889795560185 1.6031886600152079 0.6676452481167886 0.7884316662020098 0.6717846396867923 0.7774506472064451 1.3775517799981254 1.0 10.409552805711087 -6.271843794297003 24.988873919802753 0.854312945723892 1.2898953070591401 0.3278379794720637 0.31313023339451035 881.7722445112231 2117798.4669503216 0.09721148183211348 0.11141793389886208 5.34756664442762e-07 6.271843794297003 0.4355823613352481 QVQSLTCEVDALK ddPTM_PC-9_Lapatinib_30min_R1 4 QVQSLTCEVDALK 13 0 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 0 ;;; 244.73 2.4348e-33 44908600.0 86568.0 83817.0 73708.0 78905.0 77705.0 64038.0 86221.0 78903.0 66632.0 80440.0 False True 85333.52444537298 83622.92688620095 67648.0127611081 84707.93691936377 73134.5446739079 61299.244019869126 90685.10149740695 82569.1214295633 59127.20249393378 94343.94682043727 0.904493900470227 0.8863623974239556 0.7170360689897896 0.8978629766315215 0.7751906416752232 0.6497422048341757 0.9612180171983464 0.8751925715670478 0.6267196199292919 1.0 16.525642335930705 -5.308399041339137 0.0062762161521084225 1.6294039895162806 5.389397807039634e-05 0.021185678359824323 0.12160113683524063 117498.00726231268 137.69162467783045 17199.99846513073 18560.208059213717 4.9158764428535124e-06 5.308399041339137 -1.6293500955382103 QVS(ph)ASELHTSGILGPETLR ddPTM_PC-9_AZD4547_30min_R2 3 QVSASELHTSGILGPETLR 19 0 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 1 QVS(0.973)AS(0.027)ELHTSGILGPETLR;QVS(0.499)AS(0.499)ELHT(0.001)SGILGPETLR;QVS(0.984)AS(0.016)ELHTSGILGPETLR 126.8 1.7859e-05 113399200.0 71414.8 83519.7 88447.0 302609.0 151371.0 92678.0 70832.9 161627.0 69335.5 89592.0 True False 94123.22087988147 110515.80970824895 87274.13498975693 232847.17031244436 130355.7495036528 86882.83000918588 77136.89087849048 136651.2609689731 73000.43297877125 86455.41134968228 1.0886909148946795 1.278298350362948 1.0094698946808915 2.6932631130590305 1.5077801084816866 1.004943804590494 0.8922158795416333 1.5805981237688633 0.8443708940728962 1.0 16.39966864628599 -6.740686846691049 11.321268619750223 1.089952894315545 1.5398473529665415 0.18320720982022265 0.4732970085343112 1.0291142882375819 553.0623568847175 0.16474935324169956 0.16256625020040585 1.816825234468521e-07 6.740686846691049 0.44989445865099653 QVS(ph)ASELHTSGILGPETLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 QVSASELHTSGILGPETLR 19 0 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 1 QVS(0.997)AS(0.003)ELHTSGILGPETLR;QVS(0.5)AS(0.5)ELHTSGILGPETLR;QVS(0.872)AS(0.128)ELHTSGILGPETLR 164.05 6.1126e-08 47272400.0 69997.0 83206.0 169291.0 117108.0 156031.0 146216.0 119661.0 106814.0 118350.0 75654.0 True False 81846.10959623188 91466.14179070311 173327.53947969267 110546.81842925874 125457.8456279054 138548.17556144274 108325.84380938293 104010.24567878802 120080.64485379733 89369.47132326534 0.9158173186476608 1.023460701248346 1.9394490860613463 1.2369639966806019 1.403810985678789 1.5502852765044255 1.212112393700406 1.1638229939009528 1.34364277952864 1.0 16.44749446943308 -7.488527948997539 23.696811883143557 1.1898331185730517 1.3573102270127857 0.07836748349985256 0.27559256193594606 963.964088364918 664990.0568406222 0.11952890795421767 0.08052100868517757 3.246923459373256e-08 7.488527948997539 0.16747710843973396 QVS(ph)ASELHTSGILGPETLR ddPTM_PC-9_Lapatinib_30min_R1 2 QVSASELHTSGILGPETLR 19 0 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 1 QVS(0.828)AS(0.172)ELHTSGILGPETLR;QVS(0.944)AS(0.056)ELHTSGILGPETLR 104.97 0.00014119 32280000.0 24828.0 30279.0 66232.0 29698.0 54668.0 54321.0 50017.0 54272.0 76633.0 52127.0 True False 24473.94816710244 30208.89083583622 60786.66062291342 31882.089989623782 51452.535721423315 51997.817458435784 52606.635524939426 56793.6752496768 68001.78455873484 61137.08249513848 0.4003126607987643 0.4941173115062922 0.9942682598200049 0.5214853030018074 0.841592919084988 0.8505119206918414 0.8604701660260387 0.9289562558729056 1.112283769251538 1.0 15.899760086988206 -4.7532346964412655 0.323471496526277 1.0347905327934324 2.9436645324046557e-14 0.6351979321714546 0.13914196982779428 5.024591866950908 0.42019652825736475 0.14726160178736547 2.070294149782929 1.765083696620407e-05 4.7532346964412655 -1.0347905327934028 QVS(ph)ITGFFQR ddPTM_PC-9_AZD4547_30min_R2 1 QVSITGFFQR 10 0 Q15054-3;Q15054-2;Q15054;H0YEX7 Q15054-3 POLD3 DNA polymerase delta subunit 3 1 QVS(0.862)IT(0.138)GFFQR 71.933 0.031876999999999996 4479900.0 11627.0 13444.0 15796.0 24538.0 22264.0 15744.0 16274.0 22566.0 17338.0 22035.0 True False 15324.14414337622 17789.51008825104 15586.534719076939 18881.143208320853 19173.027904614028 14759.525191141602 17722.35447308458 19078.943215093026 18254.45128377146 21263.56135693201 0.7206762727157408 0.8366195008274843 0.7330161894068448 0.8879577080894552 0.9016846981920806 0.6941229149429352 0.8334612521202625 0.8972600071470724 0.8584851322575103 1.0 14.376095628426564 -14.522878745157078 0.11260280863951498 1.607693493996566 0.7173809204099492 0.46614944964383775 0.06624731935157713 156.62988194649995 1.160794325018403 21.62911486574173 0.7951395541278082 3.0000000008514486e-15 14.522878745157078 -0.8903125735866168 QVS(ph)PAASLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QVSPAASLR 9 0 A0A2R8YH03;Q5VWN6 A0A2R8YH03 FAM208B Protein FAM208B 1 QVS(0.996)PAAS(0.004)LR 80.245 0.018969999999999997 2988700.0 25085.0 24966.0 30710.0 23359.0 33289.0 29196.0 29968.0 26017.0 21624.0 22544.0 True False 29331.395048666127 27444.45948545406 31442.242868323552 22050.270960899776 26766.259417085985 27664.910363379422 27129.21409046873 25334.081317290107 21940.21009141117 26631.04874179418 1.1013984215587456 1.0305436992566999 1.1806610837288878 0.8279910856944424 1.0050771817739046 1.0388216638259056 1.0187061859074569 0.9512986725727913 0.8238582830190494 1.0 14.700821623148434 -5.011489124798564 0.45739860342133803 0.9447610338931927 1.191880465117558 0.2400093866340811 0.09087960739298423 6.447809742605556 1.2247639409030657 0.0682379804166693 0.8463613899196495 9.738921723318891e-06 5.011489124798564 0.24711943122436542 QVT(ph)RHLEDVFSKRNS(ph)SNK ddPTM_PC-9_Lapatinib_30min_R1 1 QVTRHLEDVFSKRNSSNK 18 3 J3KRP0;Q96KN2 J3KRP0 CNDP1 Beta-Ala-His dipeptidase 2 QVT(1)RHLEDVFS(0.007)KRNS(0.496)S(0.496)NK 77.562 0.030868 0.0 8030.3 8644.5 5243.1 8627.7 7703.0 8156.2 6409.7 7918.9 7329.4 6325.7 True False 7915.78644942334 8624.484191366495 4812.032556951289 9262.20983916349 7249.924684680684 7807.378339030833 6741.562903097032 8286.84100336575 6503.885789996371 7419.08881653457 1.0669486031467643 1.1624721585952063 0.6486015568686738 1.2484295670542782 0.9771987994702425 1.0523365513067995 0.9086780155633711 1.1169620971374896 0.8766421255803639 1.0 12.857026296226742 -8.279302323801925 24.570516298151936 0.938321106711873 1.0180866324498021 0.04379623685302836 0.15652853755115018 2881.9334066777515 3964058.126386455 0.1407871431037554 0.03670756534199036 5.25651219370321e-09 8.279302323801925 0.07976552573792917 QVT(ph)T(ph)ISHS(ph)S(ph)TLT(ph)IQKCGQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QVTTISHSSTLTIQKCGQK 19 1 J3KTH2;Q92750-2;Q92750 J3KTH2 TAF4B Transcription initiation factor TFIID subunit 4B 5 QVT(0.661)T(0.661)IS(0.665)HS(0.694)S(0.717)T(0.656)LT(0.944)IQKCGQK 40.52 0.041647 1199900.0 425.08 0.0 0.0 0.0 0.0 0.0 0.0 499.17 0.0 0.0 True False 497.03764828730294 0.0 0.0 0.0 0.0 0.0 0.0 486.06731641433305 0.0 0.0 0.0 QVVESAYEVIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QVVESAYEVIK 11 0 P00338-3;P00338;P00338-4 P00338-3 LDHA L-lactate dehydrogenase A chain 0 156.71 0.0036198 3916000.0 14786.0 13554.0 11550.0 15439.0 17712.0 15297.0 15522.0 13719.0 11292.0 11161.0 False True 17288.977763188246 14899.55154473461 11825.395803618918 14574.002883913354 14241.460746655861 14494.798391170534 14051.643790451672 13358.890786482041 11457.124137634803 13184.400949572615 1.311320690967661 1.1300893837893782 0.896923254143166 1.105397426827025 1.080175034203394 1.0993899871985005 1.0657779480612024 1.0132345669383698 0.8689908765256563 1.0 13.686544401513043 -4.880670374999206 3.543200021080158 1.0260570979380972 1.3181129186853686 0.5784297274169365 0.07707382732436618 0.18836436270013393 4.027565012528072 0.020115079502911016 0.12461326435846086 1.316223453102281e-05 4.880670374999206 0.29205582074727143 QVVESAYEVIK ddPTM_PC-9_Lapatinib_30min_R1 2 QVVESAYEVIK 11 0 P00338-3;P00338;P00338-4 P00338-3 LDHA L-lactate dehydrogenase A chain 0 ; 174.77 0.006477299999999999 28606400.0 102656.0 96518.0 102384.0 85638.0 108736.0 80477.0 107721.5 90665.0 81128.0 87724.0 False True 101192.10661519541 96294.51850104838 93966.38273366925 91936.10419999331 102340.36226320118 77035.18631104975 113298.79218465253 94877.62688885503 71990.51032428654 102886.97651511773 0.9835268762157349 0.9359252430447241 0.9132971530158851 0.8935640575120277 0.9946872357373994 0.7487360297707899 1.101196633647845 0.9221539022960225 0.6997047902725434 1.0 16.650700851166654 -4.722973642680677 1.6917865522268989 0.9096355444767413 1.0174516644075513 0.04088017264816102 0.11067233939596459 4.527909426940831 11.515302824634704 0.029797111638957055 0.8378638877366221 1.892458468408567e-05 4.722973642680677 0.10781611993080997 QVVNIPSFIVR ddPTM_PC-9_Lapatinib_30min_R1 1 QVVNIPSFIVR 11 0 P46781 P46781 RPS9 40S ribosomal protein S9 0 126.71 0.0018297 1907800.0 8601.7 8905.5 10193.0 10257.0 11231.0 10446.0 6891.1 8342.4 8329.5 10874.0 False True 8479.038180641415 8884.879861902284 9354.970886117844 11011.333996348956 10570.414660995553 9999.248930815334 7247.887439588744 8730.018359428512 7391.343996476483 12753.556411305775 0.6648371565695131 0.6966590004671962 0.733518603314825 0.8633932090179667 0.8288209437506459 0.784036123598528 0.5683032407465289 0.6845163872635184 0.5795515978526745 1.0 13.638611987536095 QVVQT(ph)PNTVLSTPFR ddPTM_PC-9_Lapatinib_30min_R1 1 QVVQTPNTVLSTPFR 15 0 Q99459 Q99459 CDC5L Cell division cycle 5-like protein 1 QVVQT(0.775)PNT(0.215)VLS(0.008)T(0.002)PFR 129.29 3.8026e-05 2701900.0 12697.0 11201.0 14428.0 10886.0 11138.0 10734.0 11391.0 8307.7 12681.0 13128.0 True False 12515.938451655365 11175.064772687392 13241.785533690594 11686.592754631445 10482.88473815052 10274.931842176127 11980.77024340894 8693.706070749928 11252.73224315004 15397.157308039572 0.8128733246831357 0.7257875300690974 0.8600149539796181 0.7590097652979964 0.680832476308917 0.6673265484409325 0.7781157264109541 0.5646305936103244 0.7308318034313038 1.0 13.910376398251707 -6.003809496775905 24.43680869170863 0.7143239281016402 0.7950699744045049 0.03742595503436452 0.11001186923031589 278.44574072627404 1786186.3144769566 0.02932023181750319 0.04238551536342339 9.912666685491966e-07 6.003809496775905 0.08074604630286464 QVVQTPNT(ph)VLSTPFR ddPTM_PC-9_AZD4547_30min_R2 1 QVVQTPNTVLSTPFR 15 0 Q99459 Q99459 CDC5L Cell division cycle 5-like protein 1 QVVQT(0.237)PNT(0.757)VLS(0.005)T(0.001)PFR 115.26 0.00039809 3426200.0 5526.4 7771.0 10844.0 20065.0 17783.0 12380.0 8899.4 19495.0 13614.0 12646.0 True False 7283.680243739087 10282.823779812468 10700.20147465627 15439.32425115975 15314.137406923795 11605.87664293274 9691.429359577796 16482.495700533498 14333.608246468159 12203.267389142824 0.5968631196444434 0.8426287363793271 0.8768308628700685 1.2651795423982946 1.2549210730684057 0.9510466560175861 0.7941667629277881 1.3506625049614072 1.1745713495732042 1.0 13.57497985643576 -5.210975768346505 1.6970588687422101 1.1092904292179309 0.618110596143079 0.48578079640339344 0.16583592495660332 0.44065935611650536 2.0884410939426603 0.05108667236135281 0.26656403036604687 6.152111977342721e-06 5.210975768346505 -0.4911798330748519 QVVQTPNT(ph)VLSTPFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QVVQTPNTVLSTPFR 15 0 Q99459 Q99459 CDC5L Cell division cycle 5-like protein 1 QVVQT(0.137)PNT(0.827)VLS(0.027)T(0.009)PFR 102.15 0.005463399999999999 0.0 10969.0 8203.2 8696.1 12259.0 11681.0 12286.0 11976.0 14162.0 10757.0 8891.7 True False 12825.835052374663 9017.559482939865 8903.448004142898 11572.167974214242 9392.191902760116 11641.700531733104 10841.546581268472 13790.262505879331 10914.300774755364 10503.694823341533 1.2210784174605702 0.858513088451585 0.8476491514545402 1.101723552411131 0.8941798158385741 1.1083433713118427 1.0321650394084334 1.3128963415077823 1.0390915728531425 1.0 13.358609285122927 -6.827995946230725 10.212286958396758 1.1142249929200783 0.9765864032492624 0.1479585601769715 0.13331123011175935 0.6923397690337386 101.70229662423431 0.045936570946371234 0.040535852576594276 1.4859495122959863e-07 6.827995946230725 -0.13763858967081588 QVVQTPNT(ph)VLSTPFR ddPTM_PC-9_Lapatinib_30min_R1 1 QVVQTPNTVLSTPFR 15 0 Q99459 Q99459 CDC5L Cell division cycle 5-like protein 1 QVVQT(0.084)PNT(0.353)VLS(0.353)T(0.209)PFR 92.773 0.011934 0.0 11213.0 9900.6 11598.0 10886.0 11486.0 9634.1 8895.6 8942.5 10369.0 9746.4 True False 11053.100563787646 9877.675768991057 10644.457209574675 11686.592754631445 10810.416062344852 9222.072001183995 9356.170641494917 9358.001196201269 9201.134029589371 11431.052253738331 0.9669364043168395 0.864109055731132 0.9311878708360892 1.0223549411918351 0.9457061189453918 0.8067561757639655 0.8184872602988181 0.8186473990739473 0.8049245008551419 1.0 13.480670592496113 -6.751925899611387 24.96030209990863 0.8364737919582369 0.944918637282774 0.3442682702265317 0.06516219843263435 200.15045758899223 525129.4071728201 0.02119348851605171 0.020928482835490602 1.770411004412209e-07 6.751925899611387 0.10844484532453713 QVVQTPNTVLS(ph)TPFR ddPTM_PC-9_AZD4547_30min_R2 1 QVVQTPNTVLSTPFR 15 0 Q99459 Q99459 CDC5L Cell division cycle 5-like protein 1 QVVQT(0.216)PNT(0.216)VLS(0.547)T(0.022)PFR 159.41 0.00026523 4917200.0 12270.0 10125.0 10874.0 16369.0 17085.0 15412.0 11470.0 21305.0 16415.0 15284.0 True False 16171.604768145364 13397.70824483351 10729.803655054619 12595.379948528975 14713.042658566783 14448.285203625157 12490.80777966574 18012.801790195746 17282.663388113317 14748.91181208753 1.0964608761774453 0.9083862196432257 0.7274979870895265 0.8539870675887004 0.9975680135607462 0.9796170312567742 0.8468969059418233 1.2212970027682504 1.1717924419311558 1.0 13.848320894619276 -7.760067339777111 24.99998744362301 1.1474085640927805 0.9114730144013454 0.45508819301389025 0.10742017604782599 31.35495675395155 571356.7106216536 0.055870148527950386 0.029991574289898123 1.7375313939458667e-08 7.760067339777111 -0.23593554969143504 QVVSVVQDEEVGLPFEAS(ph)PESPPPASPDGVTEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QVVSVVQDEEVGLPFEASPESPPPASPDGVTEIR 34 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 1 QVVSVVQDEEVGLPFEAS(0.69)PES(0.305)PPPAS(0.005)PDGVTEIR 131.32 3.1127e-22 4675200.0 16841.0 19721.0 18306.0 22068.0 26861.0 21895.0 22999.0 18748.0 21139.0 19683.0 True False 19691.84867508813 21678.770548451477 18742.4844658916 20831.601505421313 21597.7798733019 20746.787656055363 20820.368221659446 18255.88486514799 21448.117883941035 23251.372089457745 0.8469112532079982 0.932365215482518 0.8060807935885 0.8959299874980898 0.9288819511470642 0.8922822952655783 0.8954468640196711 0.7851530135473284 0.9224452561948242 1.0 14.505028233329204 -8.531845695616342 24.047293397498848 1.0000000044728574 0.8752418585141506 0.4242226342153047 0.04579173609749021 707.3969321526309 1897076.9175625418 0.04347196188750375 0.011224412305273207 2.9386935813101843e-09 8.531845695616342 -0.12475814595870682 QVVSVVQDEEVGLPFEASPES(ph)PPPASPDGVTEIR ddPTM_PC-9_AZD4547_30min_R2 3 QVVSVVQDEEVGLPFEASPESPPPASPDGVTEIR 34 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 1 QVVSVVQDEEVGLPFEAS(0.037)PES(0.963)PPPASPDGVTEIR;QVVSVVQDEEVGLPFEAS(0.003)PES(0.997)PPPASPDGVTEIR;QVVSVVQDEEVGLPFEAS(0.036)PES(0.962)PPPAS(0.001)PDGVTEIR 142.07 3.6986e-24 14497000.0 39951.6 38404.4 52668.4 71642.5 65206.4 58237.6 46770.9 64156.3 47136.3 51080.2 True False 52655.37775509672 50817.87126102557 51969.98260307876 55126.42849059118 56153.61690439383 54595.99366562677 50933.41949276094 54242.41800010962 49627.828587336335 49291.897745602815 1.0682359609454062 1.0309578974479408 1.0543311371637105 1.1183669327381263 1.1392058223078483 1.1076058371174624 1.0333020602215415 1.1004327380547734 1.006815133056294 1.0 15.589062905607593 -8.272555177693567 23.178761610640713 1.0034074951660146 1.081369494173201 0.4584029917638053 0.03397675325737053 306.8603212451038 639849.3218014291 0.03487668181639616 0.00941682473301929 5.338814389156544e-09 8.272555177693567 0.07796199900718648 QVVSVVQDEEVGLPFEASPES(ph)PPPASPDGVTEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QVVSVVQDEEVGLPFEASPESPPPASPDGVTEIR 34 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 1 QVVSVVQDEEVGLPFEAS(0.082)PES(0.916)PPPAS(0.002)PDGVTEIR;QVVSVVQDEEVGLPFEAS(0.03)PES(0.97)PPPASPDGVTEIR 118.77 4.5130999999999996e-24 7336000.0 19546.9 21448.5 24139.0 21937.7 30716.6 23696.2 27736.6 23067.5 23097.3 21483.1 True False 22855.804101127036 23577.7653318017 24714.56530766729 20708.60179198303 24697.902730958078 22453.529557224 25109.188452405742 22462.002567036532 23435.054316701422 25377.81596987397 0.9006213981636239 0.9290699152279648 0.9738649431852597 0.8160119774123287 0.9732083627794048 0.8847699732663602 0.989414868569182 0.8851038479316423 0.9234464598735053 1.0 14.631280294866695 -7.225524143268597 24.998915874123753 0.9399167041374269 0.9147634132106879 0.09368764208232727 0.052250091404462407 2029.544195404356 1412673.0557452366 0.01918832382084332 0.014862771664623029 5.949436817719078e-08 7.225524143268597 -0.025153290926739014 QVVSVVQDEEVGLPFEASPES(ph)PPPASPDGVTEIR ddPTM_PC-9_Lapatinib_30min_R1 2 QVVSVVQDEEVGLPFEASPESPPPASPDGVTEIR 34 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 1 QVVSVVQDEEVGLPFEAS(0.027)PES(0.972)PPPAS(0.001)PDGVTEIR;QVVSVVQDEEVGLPFEAS(0.01)PES(0.99)PPPASPDGVTEIR 121.21 2.7854000000000004e-24 12958600.0 48238.0 45671.0 51197.0 45780.0 56766.0 62709.0 50682.0 55319.0 65398.0 43959.0 True False 47550.11727423421 45565.2516055179 46987.78028613512 49146.813917603096 53427.135486250016 60027.08225181877 53306.065971069445 57889.322691938265 58032.188568529855 51557.25457831439 0.9222779153611949 0.8837796344703583 0.9113708763286003 0.9532473037901993 1.0362680465286476 1.1642800366850197 1.033919792802362 1.1228162392550518 1.1255872533007005 1.0 15.653887821842778 -6.2559684167037375 2.265868332691324 1.0940877804898714 0.905489367159379 0.7602448208334369 0.045813107792021295 0.13625465669325143 1.374959159518128 0.01461450858669944 0.018795734120279465 5.54666048596275e-07 6.2559684167037375 -0.18859841333049243 QVVSVVQDEEVGLPFEASPESPPPAS(ph)PDGVTEIR ddPTM_PC-9_AZD4547_30min_R2 3 QVVSVVQDEEVGLPFEASPESPPPASPDGVTEIR 34 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 1 QVVSVVQDEEVGLPFEASPES(0.007)PPPAS(0.967)PDGVT(0.027)EIR;QVVSVVQDEEVGLPFEAS(0.009)PES(0.015)PPPAS(0.488)PDGVT(0.488)EIR;QVVSVVQDEEVGLPFEAS(0.001)PES(0.045)PPPAS(0.916)PDGVT(0.038)EIR 101.26 2.0560999999999998e-16 8740500.0 15541.6 17506.0 26821.9 31563.0 29505.0 26205.6 19974.03 29256.46 21040.8 23759.9 True False 20483.505514637982 23164.472151511665 26466.224080881882 24286.637993488923 25408.74004337212 24566.95968934071 21751.679975176714 24735.546353569112 22152.973732355447 22928.0731329507 0.8933810266507067 1.0103104616419436 1.1543152330078008 1.0592533377166258 1.1081934315211326 1.0714794717762266 0.9486920182541048 1.0788323209777637 0.9661943070357129 1.0 14.48482749598829 -9.865978579741054 10.881169863157137 0.9999946924538732 1.0383244441365191 0.010697529446927811 0.07519561622540685 0.0 0.0 0.07416649899835144 0.017988018191321734 1.3615118332542806e-10 9.865978579741054 0.03832975168264596 QVVSVVQDEEVGLPFEASPESPPPAS(ph)PDGVTEIR ddPTM_PC-9_Lapatinib_30min_R1 2 QVVSVVQDEEVGLPFEASPESPPPASPDGVTEIR 34 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 1 QVVSVVQDEEVGLPFEASPES(0.007)PPPAS(0.953)PDGVT(0.04)EIR;QVVSVVQDEEVGLPFEASPESPPPAS(0.821)PDGVT(0.179)EIR 96.42 6.0014e-16 5138700.0 6814.4 6075.9 6662.9 4977.799999999999 10284.400000000001 11056.3 7811.6 8849.1 11712.3 9847.900000000001 True False 6717.225406392089 6061.831626852181 6115.102081537775 5343.884017454013 9679.491811908356 10583.447822494129 8216.046425547649 9260.2614912278 10393.137438013266 11550.096393498081 0.5815731035953458 0.5248295269868553 0.5294416490740426 0.46267007957286455 0.8380442450122972 0.9163081815015752 0.7113400741982313 0.8017475504741847 0.8998312294487772 1.0 13.495617271523367 -6.269318598697076 24.686640932458925 0.8465605022432914 0.5249867303594571 0.8217031890760289 0.07662684885786811 208.43219580538656 653044.6989484631 0.023489657734732335 0.027121740056390932 5.378750522800758e-07 6.269318598697076 -0.3215737718838343 QVYDAHTK ddPTM_PC-9_Lapatinib_30min_R1 2 QVYDAHTK 8 0 Q03135;E9PCT5;C9JKI3;Q03135-2 Q03135;C9JKI3 CAV1 Caveolin-1;Caveolin 0 ; 109.66 0.0031678 4999200.0 98633.0 91075.0 60826.0 50620.0 60595.0 52412.0 50498.0 44436.0 82291.0 44440.0 False True 97226.475332923 90864.12143313137 55825.121075149975 54342.7636633698 57030.92123435365 50170.46093833939 53112.53935138834 46500.65878159344 73022.52101735355 52121.39478742214 1.8653851403912458 1.74331715035106 1.0710596157841428 1.042619137208579 1.0941940726443542 0.9625694236111743 1.0190160790594456 0.8921606755008581 1.401008574601216 1.0 15.669588071014447 -5.235423129304782 4.057453418990488 1.0485557835002357 1.8357709273208427 0.8450334451905337 0.1278015140341554 0.06969768803789027 2.6631336531816703 0.0320036155130119 0.08789179362915066 5.815363559001907e-06 5.235423129304782 0.787215143820607 QWDS(ph)VVLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QWDSVVLER 9 0 Q9BRX2 Q9BRX2 PELO Protein pelota homolog 1 QWDS(1)VVLER 79.20100000000001 0.02049 3451100.0 19823.0 26616.0 32959.0 29435.0 32807.0 23500.0 22557.0 24834.0 20910.0 16486.0 True False 23178.64237790347 29258.260580983937 33744.86755770356 27785.852379557575 26378.703857020046 22267.61863061435 20420.23766146235 24182.133813798013 21215.769192166485 19474.781296895806 1.1901875571561897 1.5023665803963393 1.7327469327258809 1.4267606889113829 1.3545057813421861 1.1434078920395223 1.048547726937362 1.2417152955475057 1.0893970447590178 1.0 14.249319506364994 -6.617347300753734 2.293364435976893 1.1105465182622585 1.483942025473057 0.6119693718140609 0.13612077952095386 0.21374776632719686 2.2889522943254494 0.05223098562087592 0.052824508904669845 2.4135299878272017e-07 6.617347300753734 0.3733955072107986 QWELLLEK ddPTM_PC-9_Lapatinib_30min_R1 1 QWELLLEK 8 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2;A0A0D9SFF6;A0A5F9ZHC3 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 99.815 0.019675 0.0 8750.6 9341.3 8535.9 7491.7 10326.0 7384.6 7648.2 8566.7 8507.8 8025.4 False True 8625.814839336494 9319.67079377776 7834.1112515268605 8042.664609578577 9718.644981697105 7068.777872343378 8044.186373069987 8964.740156275915 7549.561972894248 9412.579696826688 0.916413471882162 0.9901292837838864 0.8323022491026573 0.8544591247700185 1.0325166208126346 0.7509926183920134 0.8546207981412328 0.952421168800116 0.8020715060122648 1.0 13.200374459876121 -6.758654838737487 24.9999081753975 0.867960031110235 0.9196862443756152 0.08622070572938467 0.08506646707928488 207.22436341642862 1860479.5696319072 0.02830180995125538 0.027109122953634233 1.7431917476079415e-07 6.758654838737487 0.05172621326538018 QWLQEIDR ddPTM_PC-9_AZD4547_30min_R2 2 QWLQEIDR 8 0 P62820;E7END7;P62820-2;Q9H0U4;E9PLD0;Q92928 P62820 RAB1A;RAB1B;RAB1C Ras-related protein Rab-1A;Ras-related protein Rab-1B;Putative Ras-related protein Rab-1C 0 ; 115.71 0.016687 8328600.0 25149.0 28114.0 42270.0 42729.0 34839.0 33401.0 37218.0 40395.0 30543.0 29875.0 False True 33145.8588683038 37201.30070076537 41709.47218127265 32878.48920646923 30002.20621491414 31312.430189870454 40530.3298991804 34152.880934755085 32157.44062522965 28829.085343242274 1.1497367493163777 1.2904086362034237 1.4467844430260297 1.1404624466927864 1.0406922681626751 1.0861402579048625 1.4058833090478526 1.1846675164379 1.1154512965763432 1.0 14.8152374449046 -14.522878727017403 0.14132089405174905 0.2596369396259893 1.2857830643727128 0.21862100864943745 0.12541851296541617 237.7921620589694 2.0432832579162215 49.36561857554398 0.8175496292767458 3.0000001261558846e-15 14.522878727017403 1.0261461247467234 QWLQEIDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QWLQEIDR 8 0 P62820;E7END7;P62820-2;Q9H0U4;E9PLD0;Q92928 P62820 RAB1A;RAB1B;RAB1C Ras-related protein Rab-1A;Ras-related protein Rab-1B;Putative Ras-related protein Rab-1C 0 ; 110.87 0.017301 4855500.0 21172.2 25724.0 18671.4 27739.0 34624.0 24727.0 29304.0 22643.0 22111.4 22626.0 False True 24756.23528998879 28277.70871600658 19116.59698767883 26184.873761051385 27839.675750463684 23430.27259060431 26528.112977412446 22048.645242241608 22434.737394340988 26727.91469268255 0.9262314540672506 1.057984097941929 0.7152296468872107 0.9796826300190252 1.0415955030747501 0.8766217963505752 0.9925246051715062 0.8249294977089249 0.8393747754845637 1.0 14.706059662701618 -7.763186732247282 24.99930073556316 0.8741141148361231 0.9400278003388538 0.04963267347819067 0.10137859520789294 129.41950541052245 1851478.1039542991 0.05119820739387302 0.026592747526923703 1.7250959983471953e-08 7.763186732247282 0.06591368550273069 QWLQEIDR ddPTM_PC-9_Lapatinib_30min_R1 2 QWLQEIDR 8 0 P62820;E7END7;P62820-2;Q9H0U4;E9PLD0;Q92928 P62820 RAB1A;RAB1B;RAB1C Ras-related protein Rab-1A;Ras-related protein Rab-1B;Putative Ras-related protein Rab-1C 0 ; 138.06 0.014098 7475400.0 34713.0 46825.0 31111.0 25888.0 32252.0 29371.0 33451.0 29872.0 35127.0 19940.8 False True 34217.98625441543 46716.579589419416 28553.173671932902 27791.889879836377 30355.000769871673 28114.87079714507 35182.929102999944 31259.962173097476 31170.627356291443 23387.5407105542 1.463086122559852 1.9974985898511943 1.2208711478179313 1.1883203207977573 1.2979133268241938 1.2021302771888944 1.5043449646299403 1.3366074937067092 1.3327877326676307 1.0 14.513452544308445 -5.278936367067172 24.985355080457996 1.2777943443289603 1.7302923692727703 0.54313926268017 0.17179994943149446 508.38503560673263 725963.4423928575 0.042675814687331906 0.08916738054303268 5.260943442147577e-06 5.278936367067172 0.45249802494381 QWTSLS(ph)LR ddPTM_PC-9_AZD4547_30min_R2 3 QWTSLSLR 8 0 Q9UHB6;Q9UHB6-4;F8VRN8;F8VTU2;F8VVQ7 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 QWTSLS(1)LR;QWTSLS(1)LR;QWTSLS(1)LR 141.91 0.0021352 268046000.0 83378.0 68174.0 104822.0 123763.0 103771.0 88500.0 113272.0 103690.0 91490.0 95507.0 True False 109890.46962986316 90209.91228476832 103431.99179052196 95231.3524692889 89364.187867845 82966.08100965666 123352.98856305992 87667.09305915984 96325.97461946316 92163.32900006836 1.1923448384745483 0.9788048377104673 1.1222684001621213 1.0332889827495084 0.9696284719465669 0.9002070770424875 1.338417241449345 0.951214479883803 1.0451659642132904 1.0 16.49190520836472 -4.745796729133436 24.644099357027084 1.0416253489264307 1.192345336989913 0.13792431672737981 0.11563159598282369 1574.862045680385 2480942.5509925196 0.02817150979523908 0.6672524345458061 1.795573845771836e-05 4.745796729133436 0.1507199880634824 QWTSLS(ph)LR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 QWTSLSLR 8 0 Q9UHB6;Q9UHB6-4;F8VRN8;F8VTU2;F8VVQ7 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 QWTSLS(1)LR;QWTSLS(1)LR;QWTSLS(1)LR;QWTSLS(1)LR 109.83 0.0037717 226807000.0 78984.0 81223.0 85691.0 84038.0 90681.0 82408.0 72969.0 72610.0 74340.0 51866.0 True False 92354.43119489113 89286.2826558934 87734.1984249274 79329.62331487212 72912.70900900521 78086.37940900715 66056.84807018867 70704.06443665421 75427.08186253753 61268.895228969894 1.507362436514491 1.457285663830217 1.431953327982383 1.2947780928382489 1.1900444546375588 1.2744864929780129 1.0781465509264623 1.1539960721084304 1.2310827799433404 1.0 15.902867217121324 -1.5228787452803376 0.18808514965727927 1.0062364005278648 3.452751173584905 0.8548986357592717 0.06007197324794768 19.465177960506487 0.22598080533972303 0.12726135640676114 13.78007848862474 0.029999999999999995 1.5228787452803376 2.4465147730570402 QWTSLS(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 4 QWTSLSLR 8 0 Q9UHB6;Q9UHB6-4;F8VRN8;F8VTU2;F8VVQ7 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 QWTSLS(1)LR;QWTS(0.005)LS(0.995)LR;QWTSLS(1)LR;QWTSLS(1)LR 131.09 0.0034073999999999997 256754000.0 123261.0 108337.0 120912.0 102857.0 110655.0 107375.0 107560.0 99505.0 99239.0 84563.5 True False 121503.27553670108 108086.15233270536 110971.08209381741 110421.44690089347 104146.49045610041 102782.82155335034 113128.93050487796 104128.36556086197 88061.6587870016 99180.18830121915 1.2250760723269118 1.0897957967617282 1.118883559252663 1.1133417751288555 1.0500735302074458 1.0363241219223103 1.1406404085591693 1.0498907830726714 0.8878956603666693 1.0 16.59776434397098 -1.5228787452803376 0.17210183714504768 0.9605499121914355 1.8853449389248562 0.5343639850627064 0.05857385032233074 51.464776926502196 0.5619487938239903 0.15149177138313968 12.2917313779016 0.029999999999999995 1.5228787452803376 0.9247950267334207 QWYESHYALPLGR ddPTM_PC-9_AZD4547_30min_R2 1 QWYESHYALPLGR 13 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 0 99.161 0.0021625999999999998 7987000.0 23401.0 21674.0 27620.0 35735.0 36528.0 32144.0 29620.0 38432.0 28497.0 33625.0 False True 30842.03122896247 28679.6966418293 27253.7407534126 27496.847850246355 31456.717719176315 30134.030598580757 32256.122618456782 32493.217479502615 30003.293242221454 32447.798984653477 0.9505122749173073 0.8838718661747647 0.839925714724211 0.8474179670322561 0.9694561327273414 0.9286925936897279 0.9940927775628988 1.0013997403913473 0.924663434225903 1.0 14.985832999480477 -6.273600643119286 24.291497397520942 0.968954965644134 0.8777843616375096 0.5785692323451813 0.03730042915813669 382.6229834597017 764267.7061352755 0.011982964091058233 0.01369326990088494 5.325977861580334e-07 6.273600643119286 -0.09117060400662436 QWYESHYALPLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QWYESHYALPLGR 13 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 0 ; 102.33 0.0014913 11531000.0 57864.0 54749.0 64993.0 67836.0 85914.0 65479.0 69970.0 77551.0 64604.0 55527.0 False True 67659.2323339053 60184.11889646416 66542.67960732503 64035.36884727934 69079.76843880942 62045.165970808375 63341.93506106843 75515.36842207648 65548.7112812397 65593.60554850988 1.0314912828487188 0.9175302743794879 1.014469002746209 0.9762440761077215 1.0531479076526955 0.9459026600530863 0.9656724086347682 1.1512611296573558 0.9993155694538398 1.0 16.001267558827184 QWYESHYALPLGR ddPTM_PC-9_Lapatinib_30min_R1 1 QWYESHYALPLGR 13 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 0 117.27 0.00021928 5693400.0 30517.0 30053.0 34091.0 22346.0 31032.0 29577.0 36283.0 29724.0 37871.0 34984.0 False True 30081.8219838676 29983.4141249508 31288.169575065564 23989.399384070766 29206.758771259396 28312.060657354512 38161.556205917535 31105.085552796918 33605.569180690436 41030.93778675015 0.7331497549534859 0.7307513730440044 0.7625506815778713 0.5846661245899553 0.71182284263293 0.6900173913767366 0.9300678528054699 0.758088584629949 0.8190300050013104 1.0 15.3244245078192 -7.246574850195385 24.759930456858797 0.8566373251851287 0.7013029690702277 0.5586184265471643 0.07519705034241544 588.3301999858725 979986.0832721358 0.028522251984706 0.021994452714854222 5.6679387677845265e-08 7.246574850195385 -0.15533435611490098 QYAENYTRPSS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QYAENYTRPSSR 12 1 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 QYAENYT(0.001)RPS(0.182)S(0.817)R 101.3 0.013333000000000001 6503400.0 85992.0 81877.0 87181.0 100360.0 91272.0 84429.0 89702.0 91650.0 79191.0 58313.0 True False 100548.7471805817 90005.20745375784 89259.72567578386 94737.15457150998 73387.90680153406 80001.39461123997 81204.77717375955 89244.28461120185 80349.01856034694 68884.6852945461 1.4596676569057736 1.3066069340217186 1.2957847639735236 1.3753006806436079 1.0653733335317204 1.161381434337104 1.1788509568786385 1.2955606058095428 1.166427896371743 1.0 16.071895652675096 -1.5228787452803376 0.18359888755404208 1.0648950549343918 2.610071917964655 0.5916598459996585 0.0856660546651061 45.76141828181362 0.5226856680081381 0.1983668985193993 19.834447605551308 0.029999999999999995 1.5228787452803376 1.5451768630302631 QYAVGDETDLSIPT(ph)SPTSK ddPTM_PC-9_AZD4547_30min_R2 1 QYAVGDETDLSIPTSPTSK 19 0 H0Y6B3;A0A0C4DG30;J3KQY3;B4DZ31;Q9NWS1-3;Q9NWS1-6;Q9NWS1-7;Q9NWS1-2;Q9NWS1 H0Y6B3 PARPBP PCNA-interacting partner 1 QYAVGDETDLSIPT(0.49)S(0.49)PT(0.017)S(0.003)K 167.92 7.2298e-28 0.0 10021.0 9251.2 11474.0 14757.0 11493.0 10671.0 8645.9 14666.0 9189.6 10798.0 True False 13207.4695502514 12241.469482923825 11321.847263021586 11355.001643377242 9897.3953336206 10003.740683096541 9415.368350672363 12399.706691152818 9675.343495059777 10419.9653066554 1.267515693340704 1.1748090442398116 1.0865532590391773 1.0897350719704046 0.9498491638258117 0.9600550854720208 0.9035892225724221 1.1899950072993932 0.9285389356219812 1.0 13.347062853711021 -5.190427319567979 1.0223362030741134 0.9954437967777817 1.3099998205819041 0.5835157392679411 0.07689131552600248 0.7921923272039542 1.0398932288096845 0.026832468537683275 0.23559262017119434 6.450192566659094e-06 5.190427319567979 0.3145560238041224 QYDIDDAIAK ddPTM_PC-9_Lapatinib_30min_R1 2 QYDIDDAIAK 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 113.69 0.005857 7543100.0 86770.0 94878.0 85732.0 82388.0 85956.0 78508.0 83866.0 78077.0 81744.0 80425.0 False True 85532.64388833093 94658.31582028713 78683.44589509012 88447.08835831116 80900.2370759981 75150.3958510865 88208.17112051051 81704.74245410184 72537.12991751893 94326.35409042375 0.9067735598721124 1.0035192893127742 0.8341618485504282 0.9376710168774618 0.857663140445829 0.7967062500798594 0.9351381379158555 0.8661920970228268 0.7690017346369915 1.0 16.525373285165458 -5.266297995590339 24.995971984974155 0.8708204755757498 0.9551464252743788 0.17826544599666538 0.06882684438384291 579.7405231238481 2982584.434528803 0.0171031643899967 0.037513106437415115 5.4162911852216844e-06 5.266297995590339 0.08432594969862894 QYDPPAESQQSES(ph)PPRR ddPTM_PC-9_AZD4547_30min_R2 1 QYDPPAESQQSESPPRR 17 1 Q6P597;Q6P597-3;K7ENJ3;K7EL76 Q6P597 KLC3 Kinesin light chain 3 1 QYDPPAES(0.003)QQS(0.182)ES(0.815)PPRR 70.89699999999999 0.006464 52190000.0 17274.0 18310.0 28093.0 37944.0 35473.0 27004.0 31054.0 35996.0 21790.0 28281.0 True False 22766.77267847948 24228.349428434714 27720.468464359874 29196.59702895614 30548.186258550737 25315.43561112726 33817.74584043065 30433.64530579142 22941.77491483333 27290.890798066437 0.8342260737085397 0.8877815534753924 1.0157406978567323 1.0698293890437875 1.1193546771553196 0.9276148513598853 1.2391587394731227 1.115157637432181 0.8406385516906161 1.0 14.736131865732718 -5.233599137834726 2.3686826671222296 1.0556671788597176 0.8376833839794926 0.3299827371156001 0.10363328194393828 0.3527247267146316 3.697228026275983 0.028345337087952904 0.10344713697875399 5.839838839477881e-06 5.233599137834726 -0.217983794880225 QYDPPAESQQSES(ph)PPRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QYDPPAESQQSESPPRR 17 1 Q6P597;Q6P597-3;K7ENJ3;K7EL76 Q6P597 KLC3 Kinesin light chain 3 1 QYDPPAES(0.004)QQS(0.253)ES(0.743)PPRR;QYDPPAESQQS(0.058)ES(0.941)PPRR 78.708 0.0031449 41800000.0 48504.0 58516.0 80465.0 85704.0 94913.0 87314.0 102586.0 63199.0 88775.0 76260.0 True False 56714.769202332114 64325.08176122849 82383.59076521167 80902.28273611698 76315.47898867141 82735.10013248777 92868.31142167747 61540.09321487556 90073.16642920031 90085.3343261721 0.6295671723544353 0.7140461013146332 0.9145061333393656 0.8980627461867873 0.8471465367754073 0.9184080932966144 1.0308926765529784 0.6831310964785595 0.9998649292133641 1.0 16.459004637452274 -5.1339145656185865 3.0958086106294007 0.9025992002968596 0.6394851451997017 0.5171523156055197 0.09372292143478278 0.20634151118558292 3.6269949731334363 0.023610241595455383 0.08504928164851722 7.346583758894089e-06 5.1339145656185865 -0.2631140550971579 QYDPPAESQQSES(ph)PPRR ddPTM_PC-9_Lapatinib_30min_R1 1 QYDPPAESQQSESPPRR 17 1 Q6P597;Q6P597-3;K7ENJ3;K7EL76 Q6P597 KLC3 Kinesin light chain 3 1 QYDPPAES(0.002)QQS(0.246)ES(0.752)PPRR 68.458 0.007976800000000001 40598000.0 44302.0 43501.0 46403.0 50049.0 59944.0 51658.0 51375.0 111720.0 60645.0 46164.0 True False 43670.24535600819 43400.2761071935 42587.924460759976 53729.77041856965 56418.21177443844 49448.70776067955 54034.94612019441 116910.91905391181 53814.521479838724 54143.38589033657 0.8065665757302111 0.8015803850002576 0.7865766752566726 0.9923607387132259 1.042014843488166 0.9132917520310654 0.9979971742003391 2.159283486457723 0.9939260464581225 1.0 15.724497489755764 -7.549595844585733 24.99712335361737 1.4616912282616332 0.8983745316944407 0.32571665002131867 0.31282312132268525 208.74442358361065 195303.51210293735 0.13686239516002016 0.07901992830853236 2.821006945478697e-08 7.549595844585733 -0.5633166965671925 QYPDS(ph)PHPVPHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QYPDSPHPVPHR 12 0 Q5VT52-2;Q5VT52-3;Q5VT52 Q5VT52-2 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 QY(0.013)PDS(0.987)PHPVPHR 85.493 0.013263999999999998 0.0 15441.0 17125.0 25555.0 20912.0 28919.0 22164.0 25775.0 27148.0 19226.0 17597.0 True False 18054.85632634856 18825.05682481779 26164.328117877194 19740.368437618745 23252.529546778496 21001.68082250794 23333.405405159894 26435.393765683682 19507.14387798148 20787.19680222464 0.8685565686478869 0.9056082454948009 1.2586751531152625 0.9496407151687781 1.118598614715093 1.0103180829201726 1.1224892719860506 1.2717151820516066 0.9384210898457378 1.0 14.34340760036244 -5.088884712121116 9.190418139050355 1.0885790258907102 0.8777086320793406 0.34086108595995257 0.10974336077752941 0.3502138846715996 33.58781976037198 0.026438913072929438 0.07044299200247826 8.149205842516336e-06 5.088884712121116 -0.21087039381136963 QYQHGS(ph)VSDTVFDSIPANPALLTYPRPGTSR ddPTM_PC-9_AZD4547_30min_R2 1 QYQHGSVSDTVFDSIPANPALLTYPRPGTSR 31 1 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 QY(0.095)QHGS(0.725)VS(0.142)DT(0.035)VFDS(0.002)IPANPALLTYPRPGTSR 48.213 0.035824 0.0 3393.6 3322.2 3929.3 6250.3 6189.5 3881.7 4254.0 4773.7 5073.8 4658.7 True False 4472.69420873497 4396.036180838113 3877.194914640987 4809.389901172379 5330.194763546916 3638.9766853693045 4632.59775891003 4036.034353713094 5341.990709632003 4495.600330997921 0.9949047689793485 0.977852980062908 0.8624420831867715 1.0697992586242209 1.1856469372498095 0.8094528911473619 1.0304736671023642 0.8977742807526633 1.1882708239871942 1.0 12.134298067081007 -5.016921326447527 0.2884466158001497 1.0232941452447082 0.9288295435725202 0.023328413572681006 0.11771607211545414 44.31350974772321 3.392722141604599 0.14666178823826312 1.4695304631023776 9.617864926783815e-06 5.016921326447527 -0.09446460167218795 QYSS(ph)LPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QYSSLPR 7 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-5 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 QYS(0.427)S(0.573)LPR;QYS(0.223)S(0.777)LPR 82.75 0.022022999999999997 76416000.0 491570.0 456610.0 575580.0 578200.0 608330.0 520430.0 548220.0 406580.0 508410.0 430920.0 True False 574783.0920499424 501939.2231696385 589304.0100993053 545805.3285496911 489132.10343344364 493137.73463534616 496288.6328309112 395907.7058071191 515844.53443277767 509042.3848391563 1.1291458416209454 0.9860460309768464 1.1576717924687343 1.0722198088124841 0.9608867905724515 0.9687557447523047 0.9749455990540455 0.7777499823167284 1.0133626389397234 1.0 18.957426260111973 -6.307102217676631 3.083817645554378 0.9368120784777105 1.0862813928645845 0.45094846692370505 0.07390901382123159 0.2345280238720082 4.479411245022664 0.02360764676529291 0.028460643401284322 4.930577418116624e-07 6.307102217676631 0.14946931438687394 QYSS(ph)LPR ddPTM_PC-9_Lapatinib_30min_R1 2 QYSSLPR 7 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-5 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 QYS(0.076)S(0.924)LPR;QYS(0.079)S(0.921)LPR 109.44 0.009612299999999999 98513000.0 748590.0 721590.0 696380.0 602700.0 676430.0 632580.0 527070.0 569030.0 628260.0 447270.0 True False 737914.9693254064 719919.2026893578 639126.3245045366 647024.5685482627 636643.7173125475 605526.0280160028 554359.1056266832 595469.2111461468 557498.7429289048 524580.0235501877 1.4066776015057472 1.3723725082346403 1.218358107079901 1.2334144258285131 1.2136255456392506 1.154306303770393 1.0567674725296634 1.135135126031304 1.0627525218286695 1.0 19.000803344041586 -1.5228787461055335 0.1983825470559552 0.9876218109205409 3.0737363732946488 0.93023672802751 0.03315467050840691 12.688095006266991 0.15251269660904299 0.06331829799453956 8.206803372965586 0.02999999994299748 1.5228787461055335 2.086114562374108 QYT(ph)SPEEIDAQLQAEK ddPTM_PC-9_AZD4547_30min_R2 2 QYTSPEEIDAQLQAEK 16 0 Q13442;F8WBW6 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 1 QYT(0.95)S(0.05)PEEIDAQLQAEK;QYT(0.988)S(0.012)PEEIDAQLQAEK 222.09 1.3311e-22 10852200.0 46685.0 39358.0 55219.0 72952.0 57846.0 53207.0 47323.0 59201.0 51624.0 59235.0 True False 61529.85889167618 52079.70381236126 54486.75998054637 56134.04349716454 49815.08139464174 49879.95787887904 51534.65532320153 50052.84575364364 54352.739247515216 57161.200679730784 1.0764269847378225 0.911102342026706 0.9532123071702242 0.9820305177226539 0.8714841676218681 0.8726191417558229 0.9015670544071617 0.8756437086422548 0.9508676969899367 1.0 15.802748600330633 -4.759663712866569 24.984262859196186 0.9191292952439941 1.076427182902716 0.5154170442917699 0.044003100015560015 37.094733072134694 521785.2465373322 0.011159228668823547 0.06984598263578913 1.7391469807294698e-05 4.759663712866569 0.157297887658722 QYT(ph)SPEEIDAQLQAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 QYTSPEEIDAQLQAEK 16 0 Q13442;F8WBW6 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 1 QY(0.007)T(0.93)S(0.063)PEEIDAQLQAEK;QY(0.007)T(0.942)S(0.051)PEEIDAQLQAEK 132.23 1.7978e-05 8931900.0 89705.0 89819.0 100160.0 106291.0 111623.0 101387.0 98865.0 84538.0 89891.0 68494.0 True False 104890.2847454889 98735.63672690872 102548.19425891509 100335.8598700716 89751.27444240988 96070.0872383872 89499.79147938447 82318.9670754149 91205.48581793586 80911.42000179422 1.2963594600510404 1.2202929663664195 1.2674131075272326 1.2400704358896018 1.1092534828880722 1.1873489210331105 1.106145355963346 1.017396148449619 1.127226364534368 1.0 16.30405572147791 -6.6910925762386 0.39744925547894167 1.008885808725073 1.315127085568443 0.7936338291947413 0.04388645616020024 0.6675522728134088 0.2137512591591992 0.04500246010185329 0.0811217377066539 2.0366078985870955e-07 6.6910925762386 0.30624127684337 QYTS(ph)PEEIDAQLQAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 QYTSPEEIDAQLQAEK 16 0 Q13442;F8WBW6 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 1 QYT(0.031)S(0.969)PEEIDAQLQAEK 156.49 9.129700000000002e-15 0.0 20330.0 23054.0 21335.0 20414.0 24292.0 21972.0 23749.0 19978.0 18387.0 14044.0 True False 23771.467464197016 25342.64876142186 21843.707313438084 19270.26976308097 19532.156981581094 20819.749640504608 21499.322792129682 19453.59866844072 18655.87509021354 16590.06602775717 1.4328735897991305 1.527579740732832 1.3166739226288156 1.1615547358786578 1.1773405210625114 1.2549527895591657 1.2959154445894752 1.172605258827332 1.1245208463305707 1.0 14.018032007719553 -1.5228787452803376 0.1907869278549752 1.0434821819130788 3.0814176462573633 0.7215460982341053 0.07724428184492875 33.069185632597765 0.3875690390685522 0.17492359552311967 19.863765302062873 0.029999999999999995 1.5228787452803376 2.0379354643442844 QYTS(ph)PEEIDAQLQAEK ddPTM_PC-9_Lapatinib_30min_R1 3 QYTSPEEIDAQLQAEK 16 0 Q13442;F8WBW6 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 1 QYT(0.009)S(0.991)PEEIDAQLQAEK;QYT(0.1)S(0.9)PEEIDAQLQAEK;QYT(0.146)S(0.854)PEEIDAQLQAEK 191.4 1.4557e-08 12833500.0 111740.0 139898.0 163273.0 142916.0 169276.0 160414.0 130046.0 131060.0 156390.0 128539.0 True False 110146.56710939352 139574.0747763075 149849.32419200605 153426.51939379997 159319.51848942065 153553.46716329825 136779.14556003493 137149.52605805252 138775.71134029154 150756.79488254836 0.7306242295427317 0.9258227789005922 0.9939805652458366 1.0177088171271587 1.0567982598299688 1.0185508870955284 0.9072834539006807 0.9097402618893762 0.9205270744075513 1.0 17.201863502913312 -4.767905409099759 2.9185562196272428 0.9776226548180675 0.6833840846746031 0.7029305168873232 0.048171363449007895 0.27021507948915635 3.1711352711987737 0.014382125806859101 0.19346499156208918 1.7064540203537855e-05 4.767905409099759 -0.29423857014346444 RAAEDDEDDDVDTK ddPTM_PC-9_AZD4547_30min_R2 2 RAAEDDEDDDVDTK 14 1 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 0 ; 203.11 7.983699999999999e-11 21749500.0 116544.0 98690.0 106657.0 160315.0 148671.0 118085.0 119345.0 134770.0 125435.0 127807.0 False True 153602.56773420825 130589.61251186363 105242.65849155425 123356.85359205963 128030.59789826046 110701.12628277135 129966.4737981 113944.39320650927 132065.23801937222 123332.51583142292 1.24543448010223 1.058841714462065 0.8533245088051654 1.0001973345023625 1.0380928097928297 0.8975826491213656 1.053789204914499 0.9238795822689143 1.0708063249101771 1.0 16.912193681674587 -4.840053799552034 3.606774322532427 0.9783231723433963 1.2597414853096214 0.5901829692622165 0.06678681589267577 0.15928368373646312 3.4747305686027343 0.015915558662512697 0.1090332415864754 1.4452607235809971e-05 4.840053799552034 0.2814183129662251 RAAEDDEDDDVDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RAAEDDEDDDVDTK 14 1 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 0 ; 201.76 1.3486e-08 16934200.0 134895.0 111669.0 123611.0 148414.0 161290.0 124057.0 155698.0 152067.0 133666.0 131039.0 False True 157730.05920230487 122754.76032528936 126558.35503732793 140098.84474468033 129686.38232995284 117551.23253013306 140949.15828409637 148075.40237830457 135620.61237877217 154795.33339584692 1.0189587485751472 0.7930133139826475 0.817585079995205 0.9050585807158391 0.8377925838262529 0.7593977799674864 0.9105517278331464 0.9565882842194089 0.8761285589402065 1.0 17.24000245374762 -8.363019365582142 0.860904347408454 0.9898598941256398 0.8554109925992784 0.21642321637797846 0.07319725039465812 0.8512244187563175 1.3896553674799612 0.06944201104143277 0.025322251764517224 4.3349154817795255e-09 8.363019365582142 -0.13444890152636135 RAAEDDEDDDVDTK ddPTM_PC-9_Lapatinib_30min_R1 2 RAAEDDEDDDVDTK 14 1 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 0 ; 246.77 2.7721e-35 33310000.0 155830.0 115240.0 126847.0 123436.0 136599.0 117021.0 123506.0 119214.0 118066.0 97450.0 False True 153607.83562427765 114973.16886032428 116418.12930357995 132513.8952104248 128564.515383967 112016.28461927439 129900.5363605009 124753.11765210364 104768.16378990258 114294.10265603726 1.3439699166854937 1.0059413931997054 1.018583869142705 1.1594114843284535 1.1248569470891765 0.9800705549645212 1.1365462726579207 1.0915096645672289 0.9166541523598769 1.0 16.80239143977061 -4.75524754762208 24.999749302031265 1.056615676099253 1.3439703894893096 0.5846002627544884 0.07449723610572255 152.44237994374646 615432.9702377615 0.01850401001089846 0.16682326473925127 1.7569218839601704e-05 4.75524754762208 0.28735471339005647 RAAEDDEDDDVDTKK ddPTM_PC-9_AZD4547_30min_R2 2 RAAEDDEDDDVDTKK 15 2 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 0 ; 113.52 0.00083252 34445000.0 141491.0 91093.0 134929.0 142432.0 153665.0 134255.0 120378.0 133850.0 124725.0 138181.0 False True 186482.1948043732 120537.03082929575 133139.75329895748 109596.5029524637 132331.26720097545 125860.01362656968 131091.40879691395 113166.55806701245 131317.70886886574 133343.32524902324 1.3985116574535044 0.9039599890297374 0.9984733247825822 0.8219121785645324 0.9924101334194438 0.9438793684762381 0.9831118921933005 0.8486855855414586 0.9848090155515876 1.0 17.024786084318947 -4.758855658000545 24.99896642176307 0.9381311339872876 1.3985122659263918 0.8339829223629713 0.061094459769832875 24.62036763287425 238167.7456029486 0.014096939272835335 0.09351522695040003 1.7423858760778914e-05 4.758855658000545 0.4603811319391041 RAAEDDEDDDVDTKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RAAEDDEDDDVDTKK 15 2 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 0 ;;; 113.52 0.00083252 56998000.0 129796.0 109806.0 117873.0 164271.0 137176.0 139030.0 158379.0 146313.0 140656.0 119058.0 False True 151767.8992121454 120706.81399742741 120683.53935584164 155067.42844376777 110297.34752615566 131739.02205167283 143376.19455533734 142472.43878143752 142712.82790499125 140642.27293739037 1.0791058480668028 0.8582541470384397 0.8580886588029351 1.1025662854069418 0.7842403654501279 0.9366957693460984 1.0194388327268007 1.0130129142954187 1.0147221381193308 1.0 17.101670765794445 -7.241968866642484 7.714533004539774 1.0129314562984484 0.9298791680327836 0.13734179546206415 0.09156261179487002 0.3784017970780973 119.54589975514841 0.03500644370401642 0.02631472577475177 5.728370946041253e-08 7.241968866642484 -0.0830522882656648 RAAEDDEDDDVDTKK ddPTM_PC-9_Lapatinib_30min_R1 3 RAAEDDEDDDVDTKK 15 2 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1 0 ;; 124.21 0.00012107 97348000.0 229895.0 165719.0 186161.0 178703.0 203943.0 172972.0 149818.0 161539.0 170730.0 144771.0 False True 226616.65514241997 165335.2878372447 170855.56118224075 191845.41475573264 191947.47370736513 165574.39077742607 157574.84297489587 169044.69166711267 151500.5895333972 169794.47445476818 1.3346527080466848 0.9737377401011281 1.0062492418017717 1.1298684210529986 1.1304694945093654 0.9751459304497786 0.9280328083754721 0.9955841743963509 0.8922586557653599 1.0 17.373429985115678 -6.828247825112825 5.703868169153928 0.9540095717828685 1.1018060903667086 0.40320577525167733 0.0948156928983824 0.2296149068427057 13.858636769281556 0.03339749768009524 0.029670754596758605 1.4850879522193036e-07 6.828247825112825 0.14779651858384013 RAAPT(ph)TPPPPVK ddPTM_PC-9_Lapatinib_30min_R1 1 RAAPTTPPPPVK 12 1 C9JC20;C9JMQ4;C9JSC3;Q9NZQ3-5;Q9NZQ3-4;Q9NZQ3-3;Q9NZQ3-2;Q9NZQ3 C9JC20 NCKIPSD NCK-interacting protein with SH3 domain 1 RAAPT(0.958)T(0.042)PPPPVK 69.26100000000001 0.027644 47559000.0 109890.0 87535.0 101130.0 89595.0 83144.0 86646.0 74422.0 67125.0 75357.0 61131.0 True False 108322.94844864217 87332.31808563456 92815.48177308917 96184.11518015854 78253.63338739338 82940.35256169121 78275.20701035723 70243.87255186036 66869.50111561058 71697.41189806261 1.5108348485807652 1.218067929841055 1.2945443819513547 1.341528412725838 1.0914429310035936 1.1568109694058901 1.0917438292144597 0.9797267529228412 0.9326626909585493 1.0 16.129633421639518 -6.416561519516393 0.4909070200728864 0.9446597553031876 1.4344295371718874 0.7944298841089134 0.07808876784577716 0.5579942630430292 0.2706253742885134 0.06751936676516287 0.1286990319582991 3.832114531500698e-07 6.416561519516393 0.4897697818686998 RAAPTT(ph)PPPPVK ddPTM_PC-9_Lapatinib_30min_R1 1 RAAPTTPPPPVK 12 1 C9JC20;C9JMQ4;C9JSC3;Q9NZQ3-5;Q9NZQ3-4;Q9NZQ3-3;Q9NZQ3-2;Q9NZQ3 C9JC20 NCKIPSD NCK-interacting protein with SH3 domain 1 RAAPT(0.36)T(0.64)PPPPVK 75.02 0.017149 50353000.0 91588.0 76310.0 82295.0 73903.0 70506.0 85294.0 69873.0 66273.0 77314.0 55632.0 True False 90281.9383248177 76133.3088834725 75529.02276788645 79338.07315318075 66358.97570012938 81646.17445002521 73490.68204878518 69352.2855214813 68606.08316748703 65247.91707501958 1.3836754086879886 1.1668312537232004 1.1575698681851567 1.2159479828599102 1.017028261972445 1.2513223120387358 1.1263299327132295 1.0629042064552447 1.051467789977209 1.0 15.993644226465621 -1.5228787452803376 0.2138593361807681 1.0242607262877361 2.4611666856996752 0.5715199099816315 0.07381091669807137 41.757393408102615 0.525374412360697 0.12156936353866375 20.522905157563745 0.029999999999999995 1.5228787452803376 1.436905959411939 RAAS(ph)AATAAPTATPAAQESGTIPK ddPTM_PC-9_AZD4547_30min_R2 2 RAASAATAAPTATPAAQESGTIPK 24 1 B8ZZ81;O00116 B8ZZ81 AGPS Alkyldihydroxyacetonephosphate synthase, peroxisomal 1 RAAS(0.966)AAT(0.034)AAPT(0.001)ATPAAQESGTIPK;RAAS(0.961)AAT(0.039)AAPTATPAAQESGTIPK 120.29 4.584399999999999e-09 66851000.0 52131.0 46296.0 71418.0 83633.0 70080.0 61234.0 68421.0 73524.0 47673.0 61154.0 True False 68707.5736078391 61260.27663237652 70470.95065630772 64352.70396696953 60350.601668853364 57405.02829994698 74510.33645095986 62162.55521344055 50192.89745364156 59013.017073828945 1.1642782730779833 1.0380807433677914 1.194159427031907 1.0904832045184252 1.0226659245933998 0.9727519646746704 1.2626084912374977 1.053370227380026 0.8505394223590896 1.0 15.8487455983714 -8.065825201444694 6.9771393683221685 0.9313323426581276 1.1023109090237149 0.39930428539612284 0.08755506239338243 0.27061787513554597 24.221591114885815 0.058882197295260515 0.022156255127305548 8.59359334198298e-09 8.065825201444694 0.17097856636558728 RAAS(ph)AATAAPTATPAAQESGTIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RAASAATAAPTATPAAQESGTIPK 24 1 B8ZZ81;O00116 B8ZZ81 AGPS Alkyldihydroxyacetonephosphate synthase, peroxisomal 1 RAAS(0.946)AAT(0.054)AAPTATPAAQESGTIPK 100.57 1.576e-06 29645000.0 39487.0 25774.0 31805.0 44914.0 46747.0 42352.0 44637.0 37266.0 35798.0 37252.0 True False 46171.36919620006 28332.672385568105 32563.35182113419 42397.61419315268 37587.26092614735 40130.98656356508 40408.660216105636 36287.806986590804 36321.478026837656 44005.49271333028 1.049218321380451 0.6438439985239726 0.7399838023236132 0.9634618675752145 0.8541493029292069 0.9119540332156871 0.9182640103439842 0.8246199451278589 0.8253851005248498 1.0 15.425395990020078 -5.755175184065642 24.986127294428414 0.8917704200864299 0.7942982459925337 0.11361195881835051 0.10902520399878675 293.77690464186793 1171779.3879153002 0.028923852514668107 0.048539755836207454 1.7572146523783578e-06 5.755175184065642 -0.09747217409389619 RAAS(ph)AATAAPTATPAAQESGTIPK ddPTM_PC-9_Lapatinib_30min_R1 3 RAASAATAAPTATPAAQESGTIPK 24 1 B8ZZ81;O00116 B8ZZ81 AGPS Alkyldihydroxyacetonephosphate synthase, peroxisomal 1 RAAS(0.631)AAT(0.369)AAPTATPAAQESGTIPK;RAAS(0.626)AAT(0.307)AAPT(0.026)AT(0.042)PAAQESGTIPK;RAAS(0.989)AAT(0.01)AAPT(0.001)ATPAAQESGTIPK 109.48 3.6054e-07 61903000.0 182397.0 141663.0 135614.0 114856.0 110546.0 127609.0 92671.7 86072.3 135869.0 70685.9 True False 179795.98533248683 141334.98802724874 124464.34040517824 123302.89338838423 104043.9016217982 122151.46054110801 97469.78717988949 90071.53328037946 120566.00245600147 82903.86363195877 2.1687286630050004 1.7048058056098274 1.501309287076438 1.4872997226736242 1.254994605362278 1.473410950825935 1.17569655875864 1.0864576068522047 1.4542868953760588 1.0 16.339151717854058 -1.5228787452806871 0.4196484267679719 1.1915576169160795 18.804474051810274 0.8256223437754571 0.13403743658678033 30.06857549795421 0.38553957099543984 0.0878041174157438 444.4598667034445 0.029999999999975855 1.5228787452806871 17.612916434894196 up RAAS(ph)SDQLR ddPTM_PC-9_AZD4547_30min_R2 1 RAASSDQLR 9 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 RAAS(0.842)S(0.158)DQLR 80.69 0.022412 0.0 8391.5 10819.0 11540.0 8961.8 11689.0 11188.0 11078.0 11603.0 10992.0 10009.0 True False 11059.822445956961 14316.030172923834 11386.972059897955 6895.795468429775 10066.184116826871 10488.412591367649 12063.920539070357 9810.022960414984 11573.014679387239 9658.587956502495 1.145076536628846 1.4822073617174847 1.1789479074145461 0.7139548243992836 1.0422003881064175 1.0859157299806426 1.2490356347532674 1.015678793276458 1.198209793347265 1.0 13.237596573406861 -5.52209057738546 24.999925454619003 1.0461814934559968 1.3178759129443531 0.33410038658428687 0.1536747277730297 29.772136689341373 944340.8934748708 0.04217856915835361 0.07423001227357442 3.0054494143038565e-06 5.52209057738546 0.2716944194883564 RAAS(ph)SDQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RAASSDQLR 9 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 RAAS(0.622)S(0.378)DQLR 78.692 0.017988 0.0 14211.0 17379.0 17268.0 19922.0 23363.0 17365.0 13055.0 21985.0 14220.0 12902.0 True False 16616.641619955913 19104.272266190266 17679.734609254683 18805.834927995442 18785.187862698793 16454.348830664603 11818.335889984966 21407.917045032973 14427.940598403027 15241.0304678242 1.0902570961350553 1.253476417262066 1.1600091376090944 1.2338952387567894 1.2325405360455628 1.0796086829825502 0.7754289262090915 1.404623991155183 0.9466512535922219 1.0 13.895672828349277 -6.854745645437805 5.906329362620068 1.047251543281462 1.1972222746531076 0.20171279065654735 0.15259890116907268 0.3695420341553318 19.100705557947716 0.05277887956766945 0.04665978433981894 1.3971864158684558e-07 6.854745645437805 0.14997073137164563 RAASAATAAPTAT(ph)PAAQESGTIPK ddPTM_PC-9_AZD4547_30min_R2 1 RAASAATAAPTATPAAQESGTIPK 24 1 B8ZZ81;O00116 B8ZZ81 AGPS Alkyldihydroxyacetonephosphate synthase, peroxisomal 1 RAASAATAAPT(0.004)AT(0.727)PAAQES(0.251)GT(0.018)IPK 114.78 1.8297e-08 4991400.0 29709.0 26270.0 28340.0 39120.0 29383.0 30169.0 33267.0 29585.0 25227.0 31458.0 True False 39155.844014411625 34761.26376215075 27964.193082972957 30101.488397975056 25303.67763749884 28282.527660794654 36227.69855328159 25013.31804566728 26560.447718058775 30356.664995069998 1.2898598716548948 1.1450949492573073 0.9211879199350264 0.9915940503630296 0.8335460315422734 0.9316744005109854 1.193401796909017 0.8239810944229055 0.8749461682425346 1.0 14.889725683499277 -5.03504880008098 2.5347501613475343 0.9450614436516956 1.2952405479709312 0.556612768029957 0.1004897834242536 0.24937227117168806 2.830034940731078 0.027474336068604072 0.14750196379623484 9.224677670050916e-06 5.03504880008098 0.3501791043192356 RAASAATAAPTAT(ph)PAAQESGTIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RAASAATAAPTATPAAQESGTIPK 24 1 B8ZZ81;O00116 B8ZZ81 AGPS Alkyldihydroxyacetonephosphate synthase, peroxisomal 1 RAASAATAAPT(0.005)AT(0.594)PAAQES(0.235)GT(0.165)IPK;RAASAATAAPT(0.007)AT(0.975)PAAQES(0.017)GT(0.002)IPK 97.662 4.1679e-06 8664700.0 44178.0 34011.0 40131.0 58824.0 62021.0 52599.0 53923.0 51617.0 45525.0 41851.0 True False 51656.46284472679 37387.38730913156 41087.875237665 55528.28198998111 49868.43027147377 49840.61584475251 48815.02307128756 50262.108442732184 46190.71700016158 49438.2550076663 1.0448682470025796 0.7562440725979096 0.8310947712716312 1.1231845052251628 1.0087012630955676 1.008138653700941 0.9873937311039376 1.0166642903342387 0.9343112331331045 1.0 15.593340201751792 -5.740509505675959 24.997863661630333 1.0106699791683909 0.8652864840161292 0.36547175499542084 0.08031251528335097 236.01756774328288 281888.43195697275 0.02119558770929359 0.03666402217979704 1.8175672734242129e-06 5.740509505675959 -0.14538349515226168 RAASAATAAPTATPAAQES(ph)GTIPK ddPTM_PC-9_AZD4547_30min_R2 1 RAASAATAAPTATPAAQESGTIPK 24 1 B8ZZ81;O00116 B8ZZ81 AGPS Alkyldihydroxyacetonephosphate synthase, peroxisomal 1 RAASAATAAPTAT(0.066)PAAQES(0.653)GT(0.281)IPK 121.76 3.1699e-09 4813700.0 12406.0 11864.0 16770.0 21617.0 19590.0 15769.0 15167.0 16755.0 15587.0 15658.0 True False 16350.849939169626 15698.805986835043 16547.618842676653 16633.534629320726 16870.266648014236 14782.961937189526 16516.833617627737 14165.899741597272 16410.896998508822 15109.818185924274 1.082134128814432 1.0389804691005116 1.0951567145984442 1.1008428046351932 1.1165102346320703 0.9783679562048447 1.093119282733275 0.9375294637756582 1.0861081712946477 1.0 13.883198680433162 -6.755991653328851 24.999787531250636 1.0197514600222861 1.0853251683097163 0.34102314291814173 0.04702893868366782 158.02825848370932 725196.4617947197 0.014898026599014921 0.014492783487230248 1.753914209855718e-07 6.755991653328851 0.06557370828743014 RAASAATAAPTATPAAQES(ph)GTIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RAASAATAAPTATPAAQESGTIPK 24 1 B8ZZ81;O00116 B8ZZ81 AGPS Alkyldihydroxyacetonephosphate synthase, peroxisomal 1 RAASAATAAPT(0.001)AT(0.045)PAAQES(0.713)GT(0.241)IPK 64.619 0.013809 0.0 11756.0 9341.5 10791.0 10850.0 13397.0 13388.0 16177.0 14042.0 9172.7 8006.0 True False 13746.058608416133 10268.862384177248 11048.29836509539 10242.109676174608 10771.95402116918 12685.909711772982 14644.59744866234 13673.41237872883 9306.8333844565 9457.424424538875 1.4534674549182416 1.0857990424467956 1.1682142906084163 1.0829702904735603 1.1389944595506931 1.34137045587774 1.548476286066265 1.445786058120736 0.9840769502009828 1.0 13.207231627226337 -6.76216803327496 24.999966637515076 1.3095869849048867 1.1736288944047495 0.010746263362354957 0.19336517929120708 48.53747945686031 1665277.4342526628 0.0660728981762794 0.06172858747009162 1.729147203846526e-07 6.76216803327496 -0.13595809050013719 RAASAATAAPTATPAAQES(ph)GTIPK ddPTM_PC-9_Lapatinib_30min_R1 2 RAASAATAAPTATPAAQESGTIPK 24 1 B8ZZ81;O00116 B8ZZ81 AGPS Alkyldihydroxyacetonephosphate synthase, peroxisomal 1 RAASAATAAPT(0.001)AT(0.237)PAAQES(0.725)GT(0.037)IPK;RAASAATAAPTAT(0.03)PAAQES(0.853)GT(0.117)IPK 130.62 1.6279e-07 6861500.0 68066.0 50881.0 46744.0 42288.0 36348.0 41658.0 32258.0 23380.2 47593.0 19674.1 True False 67095.36635822439 50763.18817061932 42900.88875705801 45398.000588632625 34210.082102917506 39876.38444954099 33928.161400393765 24466.52944561642 42232.57516349187 23074.741970909585 2.9077406994544845 2.1999460810706646 1.8592142356843395 1.9674326432714202 1.482577016291072 1.7281399939298692 1.470359297762338 1.0603164913593168 1.830251242537604 1.0 14.494026894836729 -1.5228787452803376 0.33433448977867836 1.2810926891971028 17.745091692346023 0.7944003919037114 0.23979644764040792 24.961954040968468 0.354724893855473 0.20467662579359908 255.07415513301055 0.029999999999999995 1.5228787452803376 16.46399900314892 up RAASVAAATT(ph)SPTPR ddPTM_PC-9_Lapatinib_30min_R1 1 RAASVAAATTSPTPR 15 1 Q9Y2D9 Q9Y2D9 ZNF652 Zinc finger protein 652 1 RAASVAAAT(0.071)T(0.703)S(0.223)PT(0.003)PR 95.429 0.0024111999999999996 2794700.0 28094.0 18180.0 25845.0 17587.0 20766.0 15659.0 15871.0 16333.0 23148.0 15579.0 True False 27693.37440819139 18137.90532697587 23720.123864585054 18880.40664851215 19544.58470752682 14989.301072911874 16692.722722600593 17091.890806547963 20540.828480753666 18271.809392287345 1.5156339371557233 0.9926715486990578 1.2981814419866637 1.033307990640582 1.069657869558158 0.8203512170633173 0.9135779803858234 0.9354240972852182 1.1241814119089972 1.0 14.157331885546943 -1.5228787452803407 0.577138768870211 0.9678337805960331 26.375651466587737 0.5646247832547239 0.1270442488718094 115.68516840264819 0.969697480985834 0.0596062617285928 3679.733286662326 0.02999999999999978 1.5228787452803407 25.407817685991702 RAASVAAATTS(ph)PTPR ddPTM_PC-9_AZD4547_30min_R2 1 RAASVAAATTSPTPR 15 1 Q9Y2D9 Q9Y2D9 ZNF652 Zinc finger protein 652 1 RAASVAAAT(0.032)T(0.25)S(0.711)PT(0.007)PR 71.286 0.04493 0.0 5548.6 4687.7 7459.8 15547.0 8756.1 7944.8 5648.0 7245.2 5251.5 10130.0 True False 7312.939381950403 6202.907352030228 7360.878177853267 11962.879348755572 7540.46665628777 7448.010400062361 6150.661058374202 6125.620818133121 5529.083568850266 9775.351783332031 0.7480998683259367 0.6345456909905601 0.7530039164835287 1.2237799328258956 0.7713754781843282 0.7619173780284794 0.629200993959287 0.6266394247394684 0.5656147923267494 1.0 13.254932905950266 -6.9244205638657235 2.930737899388233 0.6761080026158184 0.8336752457866599 0.07976057078244603 0.1820454568409802 0.582132998716804 10.123355035001726 0.07362044813695684 0.062406848144583686 1.1900889865959118e-07 6.9244205638657235 0.15756724317084148 RAAVAASSS(ph)S ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RAAVAASSSS 10 1 P61927 P61927 RPL37 60S ribosomal protein L37 1 RAAVAASS(0.006)S(0.546)S(0.448) 89.88600000000001 0.013314 6783600.0 11283.0 14017.0 15975.0 10828.0 38738.0 38940.0 16703.0 24259.0 33777.0 40096.0 True False 13192.989050591968 15408.515124874206 16355.90458552487 10221.342264849647 31147.56698305978 36897.917850047765 15120.770920752113 23622.226954535134 34270.92472519403 47365.087400238626 0.27853826045142066 0.3253137695001187 0.3453156213418592 0.21579907957265063 0.657606027829326 0.7790108680315002 0.3192387420924707 0.49872655686086886 0.7235482209839936 1.0 15.531536426160658 -9.811276802457268 0.12268424541736946 1.5960521114423818 2.3517074527151546e-13 0.6338530343750459 0.1503705421733227 19.267280071843675 0.6650547628944533 6.326602452214161 2.339910220255108 1.5442698680934304e-10 9.811276802457268 -1.5960521114421466 RAAVAASSSS(ph) ddPTM_PC-9_AZD4547_30min_R2 2 RAAVAASSSS 10 1 P61927 P61927 RPL37 60S ribosomal protein L37 1 RAAVAASS(0.006)S(0.389)S(0.605);RAAVAASS(0.004)S(0.375)S(0.621) 97.965 0.007259300000000001 18962200.0 58038.0 43951.0 50352.0 74118.0 52790.0 42735.0 42144.0 53170.0 59377.0 91239.0 True False 76492.87673460638 58157.30124135088 49684.29958058766 57031.24021168489 45461.01972172904 40062.773694323936 45894.734356253946 44953.798225050836 62515.546999451966 88044.7503809901 0.8687954296378141 0.6605425194539223 0.5643073478610837 0.6477528752696493 0.5163399240160106 0.45502739823740773 0.5212659943682817 0.5105789729714185 0.7100428671662157 1.0 16.425949366285167 -8.604141724590296 4.54661239035547 0.999939412100334 0.587326600043688 0.5544896819843415 0.11030772684283134 0.35641350455693677 17.987859683650996 0.11324819566915487 0.029529879705018802 2.48804525469279e-09 8.604141724590296 -0.412612812056646 RAAVAASSSS(ph) ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RAAVAASSSS 10 1 P61927 P61927 RPL37 60S ribosomal protein L37 1 RAAVAASS(0.001)S(0.15)S(0.849) 94.40899999999999 0.0092748 6618300.0 13955.0 15241.0 18523.0 19435.0 44621.0 45251.0 16533.0 25866.0 42197.0 43031.0 True False 16317.305876186398 16754.025755740015 18964.658568868683 18346.119959120137 35877.83536452864 42877.957900167225 14966.874551445539 25187.04490729238 42814.05129611905 50832.179666791395 0.3210034663700733 0.3295948720980265 0.37308371769976 0.3609154688895947 0.7058095009836375 0.8435199549032785 0.2944370013159869 0.4954940959131652 0.8422627472748216 1.0 15.633454473940965 -8.66187358202626 0.12407571061725073 1.4200880161063434 4.857193672608769e-15 0.5624721785805837 0.16658580809462006 9.513060352160656 0.7343466384857725 4.521023304390131 3.08921341836519 2.178343770114355e-09 8.66187358202626 -1.4200880161063385 RAAVAASSSS(ph) ddPTM_PC-9_Lapatinib_30min_R1 1 RAAVAASSSS 10 1 P61927 P61927 RPL37 60S ribosomal protein L37 1 RAAVAASS(0.002)S(0.013)S(0.985) 78.77 0.029293 9114500.0 5715.2 6267.7 5616.7 4952.0 6624.9 3871.2 7894.9 7257.6 6588.5 6322.3 True False 5633.700199960684 6253.187525736337 5154.916607088991 5316.1865993877345 6235.236407054533 3705.6378002079596 8303.65929195762 7594.814591171404 5846.433750019245 7415.101131064792 0.7597603998088286 0.8433044155715235 0.6951916792466938 0.7169405386955716 0.8408835290098284 0.4997420446072646 1.1198308890448312 1.0242361441779562 0.7884496309195598 1.0 12.856250653712959 -7.276179206131655 24.99851388663794 0.9851488375712865 0.7347176247066637 0.5317181148146315 0.11805064481149288 672.6096749661193 1140731.0682001424 0.04851235454305382 0.0328585268283479 5.294449300491928e-08 7.276179206131655 -0.2504312128646228 RADDDRFPR ddPTM_PC-9_AZD4547_30min_R2 1 RADDDRFPR 9 2 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 114.5 0.0042632 1901300.0 7142.5 7343.0 13872.0 17683.0 15030.0 12068.0 10319.0 14602.0 8969.8 11518.0 False True 9413.66642677085 9716.481149808642 13688.04821619621 13606.457549626604 12943.343936684741 11313.386052254631 11237.371009448198 12345.596420579124 9443.92531579037 11114.75832580635 0.8469519669999581 0.8741963491233836 1.231520093821129 1.2241793434262087 1.1645187018266303 1.0178706293583646 1.0110315204386553 1.1107390785020492 0.8496743733836637 1.0 13.440188958957876 -8.253877763620265 24.845164773429463 0.9248371831717204 1.065544657526092 0.1493253179025622 0.12864351844165206 966.4301797945262 3175423.849150664 0.09918754518350069 0.035888891736055806 5.573425963186835e-09 8.253877763620265 0.1407074743543717 RADDDRFPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RADDDRFPR 9 2 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 78.516 0.045002999999999994 1592600.0 7717.7 6118.0 12413.0 12078.0 12777.0 11669.0 10354.0 9950.3 9481.4 9001.7 False True 9024.154178476792 6725.354607546583 12708.972996564644 11401.30881740432 10273.43857046194 11057.057097899527 9373.194163531543 9689.115168214319 9620.047537953475 10633.63695258201 0.8486423054236011 0.6324604307572833 1.195167096002719 1.072192784862371 0.9661265112090733 1.039818939390695 0.8814664451427965 0.9111760361408289 0.9046808331760452 1.0 13.37634749627275 -5.247656804431403 24.977329757932008 0.992238100164657 0.740551367270341 0.5099692457560373 0.100226728346034 660.7936171140485 1197511.6418918152 0.02664999854367865 0.06969770620029204 5.6538358535344425e-06 5.247656804431403 -0.251686732894316 RADDDRFPR ddPTM_PC-9_Lapatinib_30min_R1 1 RADDDRFPR 9 2 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 105.1 0.0055682 1748400.0 12448.0 13145.0 15555.0 11010.0 12363.0 13671.0 13519.0 10053.0 14335.0 9610.5 False True 12270.489237316384 13114.56356012639 14276.127944036394 11819.712128283316 11635.832646593193 13086.323198657527 14218.947671024966 10520.099080280823 12720.4413457579 11271.6621198137 1.088614004472944 1.1634986411696262 1.2665503802621394 1.0486219337169658 1.0323085027663614 1.1609932110770032 1.2614774573512482 0.9333227849145909 1.1285328827766659 1.0 13.46041265062341 -7.769604794959696 24.99997452202523 1.023195913089147 1.1437755825880893 0.30861642808965295 0.08593364777430373 250.71691529953918 767604.0838830738 0.04707762722626699 0.02323005883918925 1.6997897460566487e-08 7.769604794959696 0.12057966949894228 RADDNATIR ddPTM_PC-9_AZD4547_30min_R2 2 RADDNATIR 9 1 K7ER90;K7EL20;K7ENA8;O75821 K7ER90 EIF3G Eukaryotic translation initiation factor 3 subunit G 0 ; 139.43 0.00052628 3909900.0 9446.5 8502.6 12965.099999999999 24523.0 18873.6 13194.5 11174.7 14367.199999999999 12740.8 12946.0 False True 12450.290500593735 11250.899172594709 12793.174302754142 18869.601226573162 16253.326422050106 12369.445829174147 12169.226651737647 12147.079365411884 13414.252677141278 12492.764480455717 0.9966001136154908 0.9005932346036106 1.0240467050162037 1.5104424049691865 1.3010191977506336 0.9901287940331785 0.9741019828538169 0.9723291737721752 1.0737617521027616 1.0 13.608805140797383 -6.848868125269141 24.999999820361946 0.9985845442380757 1.1463121838688033 0.1663106711892356 0.16164148743181497 47.8250862786872 13665.78583302003 0.06528275404554211 0.057573989079023065 1.4162237549658578e-07 6.848868125269141 0.14772763963072755 RADDNATIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RADDNATIR 9 1 K7ER90;K7EL20;K7ENA8;O75821 K7ER90 EIF3G Eukaryotic translation initiation factor 3 subunit G 0 ; 136.52 0.00063107 1187600.0 6998.4 6427.6 8697.3 9015.3 8316.3 9865.6 9217.8 10078.9 8180.8 7422.4 False True 8183.090895299377 7065.689649471466 8904.676616693921 8510.201968996951 6686.780714059067 9348.230568603783 8344.623252907195 9814.339554477272 8300.428723446936 8768.022364313923 0.9332880956833285 0.8058475852238932 1.015585527351776 0.9705953766306177 0.7626327165033744 1.0661732121773917 0.9517109909379368 1.119333316760446 0.946670569321298 1.0 13.09803576280127 -6.800282824541352 24.999805446234614 1.0201693110453467 0.9031037743068941 0.3360451165721019 0.0835192305971061 193.16458571031416 124320.25924611879 0.028730174071192358 0.02533805404496212 1.5838614023157222e-07 6.800282824541352 -0.11706553673845255 RADDNATIR ddPTM_PC-9_Lapatinib_30min_R1 2 RADDNATIR 9 1 K7ER90;K7EL20;K7ENA8;O75821 K7ER90 EIF3G Eukaryotic translation initiation factor 3 subunit G 0 ; 141.91 0.00043731 3935900.0 28311.0 12322.9 15610.599999999999 12880.2 12801.400000000001 11733.5 9362.400000000001 9364.6 12374.400000000001 9564.6 False True 27907.279948398453 12294.367082166722 14327.156726658612 13827.452875087638 12048.446820520749 11231.68555712443 9847.13926142497 9799.71350315307 10980.664763791176 11217.82836597161 2.4877613596810737 1.0959667665678239 1.2771773875698527 1.2326318806082035 1.074044496621891 1.001235282864093 0.877811546064966 0.8735838331133432 0.9788583320725559 1.0 13.453505794455197 -2.9243817056205605 1.332430945825721 1.0149255576572047 199.99999999999943 0.9066657509265282 0.13764022639825776 59.061747379205904 1.0146078773240823 0.043365014827959215 35087.96899305383 0.00119019547387691 2.9243817056205605 198.98507444234224 up RADLNQGIGEPQS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 6 RADLNQGIGEPQSPSR 16 1 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 RADLNQGIGEPQS(0.708)PS(0.292)R;RADLNQGIGEPQS(0.5)PS(0.5)R;RADLNQGIGEPQS(0.5)PS(0.5)R;RADLNQGIGEPQS(0.99)PS(0.01)R;RADLNQGIGEPQS(0.525)PS(0.475)R;RADLNQGIGEPQS(0.985)PS(0.015)R 212.37 6.618200000000001e-18 455611000.0 325183.0 327196.8 380650.0 459635.0 409469.0 394393.7 393414.4 433292.0 386921.5 421490.0 True False 428584.42977341707 432956.7669178408 375602.3322877087 353673.25203996047 352621.2972994258 369732.1995920692 428427.51945532026 366336.67745963373 407373.38057410216 406733.76339157147 1.053722283096546 1.0644721581695293 0.9234599290595606 0.8695448567899476 0.8669585095642763 0.9090275577543336 1.0533365017028689 0.9006792905632313 1.0015725696760387 1.0 18.633725229819554 -5.259766918266377 24.76333911555133 0.9347601538953514 1.0590972344084988 0.39763921985143025 0.05799976958666569 122.52531172230587 1814128.8941794804 0.015587229449906698 0.03710982996995102 5.498358863960196e-06 5.259766918266377 0.1243370805131474 RADLNQGIGEPQS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 RADLNQGIGEPQSPSR 16 1 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 RADLNQGIGEPQS(0.748)PS(0.252)R;RADLNQGIGEPQS(0.937)PS(0.063)R;RADLNQGIGEPQS(0.982)PS(0.018)R;RADLNQGIGEPQS(0.894)PS(0.106)R;RADLNQGIGEPQS(0.5)PS(0.5)R;RADLNQGIGEPQS(0.943)PS(0.057)R;RADLNQGIGEPQS(0.875)PS(0.125)R 171.85 3.1876e-05 274244300.0 250200.0 270873.3 271462.2 290053.4 323999.5 254677.1 293734.8 251501.3 248577.9 213614.1 True False 292553.91832474584 297763.81108472496 277934.88837412704 273802.64836381015 260514.12382487222 241321.3845425887 265910.1132882076 244899.6573626545 252212.88152431577 252340.64536171468 1.1593610609396197 1.1800073296075588 1.1014273502222545 1.0850517084607239 1.0323906537190684 0.9563318037673616 1.0537744044644173 0.9705121305828716 0.9994936850652191 1.0 17.94501307924071 -5.8672114117835275 1.1035740796237419 0.9957594911153216 1.1759767778153822 0.8584921064135074 0.027400273571887717 0.18267438127375737 0.4422151246681551 0.010193760946162332 0.024619518416680728 1.3576523891780388e-06 5.8672114117835275 0.18021728670006065 RADLNQGIGEPQS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 3 RADLNQGIGEPQSPSR 16 1 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 RADLNQGIGEPQS(0.798)PS(0.202)R;RADLNQGIGEPQS(0.5)PS(0.5)R;RADLNQGIGEPQS(0.632)PS(0.368)R 113.36 0.00011164 291181000.0 298862.0 407730.0 389466.0 360090.0 419845.0 340123.0 373029.0 376274.0 359408.0 340451.0 True False 294600.17307542125 406785.9262358562 357445.60886223527 386572.2198250256 395150.54254702886 325576.73215543816 392342.6163750849 393757.063695772 318927.68630597496 399297.5017275568 0.7377961840503294 1.0187539978985614 0.8951861890338664 0.9681308251429688 0.9896143623173544 0.8153738271510179 0.9825821966769598 0.9861245361971609 0.7987219677712417 1.0 18.607104519970157 -4.746396302710292 24.92850991517071 0.9375148591329683 0.7377956320759721 0.4012821517108952 0.07384001752504699 803.2225513925117 1330976.9438505264 0.017400792038389006 0.3968115582786654 1.793096642228438e-05 4.746396302710292 -0.19971922705699618 RADLNQGIGEPQS(ph)PSRR ddPTM_PC-9_AZD4547_30min_R2 3 RADLNQGIGEPQSPSRR 17 2 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 RADLNQGIGEPQS(0.563)PS(0.437)RR;RADLNQGIGEPQS(0.841)PS(0.159)RR;RADLNQGIGEPQS(0.5)PS(0.5)RR 113.71 0.00049701 400933000.0 60236.0 40838.7 84099.0 144277.0 103872.0 76530.0 70073.0 90372.0 69652.0 91867.0 True False 79389.79501336628 54039.011130694584 82983.79231068958 111016.1667074297 89451.16576123191 71744.5670019099 76309.36125061192 76407.08394196522 73333.66252262375 88650.76429213867 0.8955342421160194 0.6095718583160217 0.936075317266592 1.2522866282527283 1.0090287035366734 0.8092943989234398 0.860786275898795 0.8618886092191402 0.82721974376849 1.0 16.43584544875266 -5.364990329600305 9.44120601028558 0.9455533562746148 0.7529742091299081 0.2382767608807359 0.13738735473192493 0.528597143069709 44.17582880925468 0.038971816841762985 0.08126433833185397 4.3152868553472025e-06 5.364990329600305 -0.1925791471447067 RADLNQGIGEPQS(ph)PSRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RADLNQGIGEPQSPSRR 17 2 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 RADLNQGIGEPQS(0.993)PS(0.007)RR;RADLNQGIGEPQS(0.954)PS(0.046)RR;RADLNQGIGEPQS(0.852)PS(0.148)RR 112.14 0.00078599 342194000.0 75602.0 72144.0 81272.0 108051.0 134242.0 118260.0 107067.0 122338.0 93552.0 72247.0 True False 88399.92539243575 79305.97953691398 83209.83270577618 101997.25277606849 107938.2437642601 112058.23741516829 96924.83866204676 119126.75712782587 94920.02101700402 85344.80919306248 1.0357973288388536 0.9292419806986997 0.9749841084950267 1.1951195830239159 1.2647312096051202 1.3130058930904176 1.1356852230202843 1.3958289701995077 1.1121944253490685 1.0 16.381015788465483 -5.788184037115273 4.8909306679804425 1.2253545703763769 0.9728846776794293 0.46477167461498115 0.10769243893225927 0.1373625347458882 8.118092070294669 0.028396390582026407 0.045162448899559525 1.6286057465995986e-06 5.788184037115273 -0.25246989269694753 RADLNQGIGEPQS(ph)PSRR ddPTM_PC-9_Lapatinib_30min_R1 5 RADLNQGIGEPQSPSRR 17 2 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 RADLNQGIGEPQS(0.696)PS(0.304)RR;RADLNQGIGEPQS(0.751)PS(0.249)RR;RADLNQGIGEPQS(0.839)PS(0.161)RR;RADLNQGIGEPQS(0.954)PS(0.046)RR;RADLNQGIGEPQS(0.853)PS(0.147)RR 95.59100000000001 0.0045974 395217000.0 264412.0 197075.0 256798.0 206870.0 201648.0 207350.0 167673.0 163527.0 226560.0 167922.0 True False 260641.43639277754 196618.6849457518 235685.05970894627 222083.90989809015 189787.46109522128 198482.1238564581 176354.28750971024 171125.06140466357 201042.42701743337 196947.09395799952 1.3234083893025674 0.9983325013553246 1.196692243446902 1.1276323272149995 0.9636469230446981 1.0077941231201206 0.8954399070611275 0.8688884814982714 1.0207940771154878 1.0 17.587448603938583 -6.2457106916969725 3.1134071852705745 0.9489479412945442 1.1576034570122862 0.5673543501452831 0.0865896285343966 0.1916544493428361 3.810707639087366 0.02662571489509895 0.03356678784357257 5.679228051684305e-07 6.2457106916969725 0.208655515717742 RADLNQGIGEPQSPS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RADLNQGIGEPQSPSR 16 1 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 RADLNQGIGEPQS(0.19)PS(0.81)R 76.329 0.0053001 37012000.0 43947.0 39226.0 33142.0 38707.0 53138.0 53316.0 39983.0 46511.0 40977.0 39125.0 True False 51386.35910718476 43120.09804439723 33932.23097173491 36538.37227978715 42725.990354324684 50520.015102546124 36195.520788147755 45290.13553247802 41576.21110413225 46218.05278667041 1.1118244064580092 0.9329708943695125 0.7341769920155786 0.7905649432795893 0.9244437568916175 1.0930796962765257 0.7831468139779957 0.9799230560734484 0.8995664810033517 1.0 15.496168858433503 -6.511309707295806 24.726235143949115 0.9470967377517574 0.8806730153262055 0.047869266793079346 0.11835228455382697 1598.9284250117555 3417362.0313359913 0.039414804448207295 0.04220275223506317 3.0809900282272886e-07 6.511309707295806 -0.06642372242555195 RADLNQGIGEPQSPS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 RADLNQGIGEPQSPSR 16 1 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 RADLNQGIGEPQS(0.012)PS(0.988)R 238.88 4.2402e-37 22633000.0 22696.0 17260.0 19699.0 15967.0 17613.0 16836.0 15194.0 15231.0 17242.0 15358.0 True False 22372.350878063346 17220.035530451238 18079.424260338983 17141.26644435057 16577.037968490313 16115.963526632871 15980.670975187037 15938.687863499179 15300.024393690815 18012.609836751344 1.242038276564275 0.9559989188971935 1.0037093138747344 0.9516259220458458 0.9203018395850657 0.8947045249240495 0.8871935338643422 0.8848627715779022 0.8494063066016115 1.0 14.13671960719879 -1.522878746557442 0.8445114628880698 0.9054021636231007 109.41374614671832 0.7971805702400293 0.04769269899010977 272.7322050625492 0.7766002072420448 0.016148476945997657 56832.34312816259 0.029999999911780748 1.522878746557442 108.50834398309523 RADLNQGIGEPQSPS(ph)RR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RADLNQGIGEPQSPSRR 17 2 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 RADLNQGIGEPQS(0.202)PS(0.798)RR 79.317 0.018183 6392100.0 18824.0 27529.0 14467.0 21847.0 17695.0 18556.0 21559.0 20294.0 15617.0 17847.0 True False 22010.531409052866 30261.897187177172 14811.948146403029 20622.983418929656 14227.791774620344 17582.89069402893 19516.775446356623 19761.304003270383 15845.369080538681 21082.519823225743 1.0440180582590879 1.435402287815657 0.7025701040767108 0.9782029658622764 0.674862013360764 0.8340032805119711 0.9257325789327989 0.9373312188944402 0.7515880081413462 1.0 14.363759690509958 -5.265868940302491 24.998968417326534 0.8486786610634097 1.2397101776479502 0.5588587664140581 0.13829825002739365 225.79378251142927 1274312.4227318866 0.033600798211183024 0.07402111872355467 5.421644780018294e-06 5.265868940302491 0.3910315165845405 RADLNQGIGEPQSPS(ph)RR ddPTM_PC-9_Lapatinib_30min_R1 1 RADLNQGIGEPQSPSRR 17 2 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 RADLNQGIGEPQS(0.181)PS(0.819)RR 91.964 0.0059791 4560800.0 20544.0 16015.0 25071.0 19735.0 21097.0 19477.0 18607.0 18578.0 21433.0 17818.0 True False 20251.0387926918 15977.918251458657 23009.75915685868 21186.377734030088 19856.11593829786 18644.014113104564 19570.379415249783 19441.20170232342 19018.98984050429 20897.8175590074 0.9690504156958332 0.7645735353150233 1.1010603902483105 1.0138081488274029 0.9501526119764336 0.8921512526588501 0.9364795802236554 0.9302981829288605 0.9100945487155288 1.0 14.351064663424914 -6.535246691408436 24.161075076188293 0.9286751266821787 0.9609420158153309 0.02383689957642121 0.08239194485810708 707.8942581840408 1382874.346571485 0.02796495259266778 0.027986028540145782 2.915770304460236e-07 6.535246691408436 0.03226688913315223 RADNCS(ph)PVAEEETTGSAESTLPK ddPTM_PC-9_AZD4547_30min_R2 1 RADNCSPVAEEETTGSAESTLPK 23 1 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 RADNCS(1)PVAEEETTGSAESTLPK 89.684 1.0117e-05 13216000.0 90086.0 80610.0 112830.0 133100.0 114940.0 127780.0 97051.0 101530.0 92814.0 94531.0 True False 118731.47409479543 106665.6060855337 111333.80047818754 102415.85137450095 98982.5650088188 119789.89640015713 105688.3509873006 85840.87142729743 97719.9585564635 91221.49846299719 1.3015733801276823 1.1693033756598639 1.2204776544352496 1.1227161699831605 1.0850793582279268 1.3131761527546968 1.1585903845919796 0.9410158008105695 1.0712382519796289 1.0 16.477086248576285 -7.649892625163566 5.883203997541772 1.0060073852833327 1.1956708237195202 0.5977271181936932 0.07258946091230813 0.1473127669516194 7.014849448814749 0.034981510293553626 0.019802295299554077 2.239274707735272e-08 7.649892625163566 0.1896634384361875 RADNCS(ph)PVAEEETTGSAESTLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RADNCSPVAEEETTGSAESTLPK 23 1 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 RADNCS(1)PVAEEETTGSAESTLPK 92.258 6.9437e-06 9349600.0 40185.0 40245.0 34723.0 41173.0 51791.0 53081.0 43809.0 50239.0 42486.0 32253.0 True False 46987.526810071686 44240.25763006082 35550.9280077108 38866.21029466702 41642.92533480431 50297.33891623998 39659.09437030652 48920.279482620535 43107.27737438472 38100.21358539246 1.2332615066516739 1.1611551082491158 0.9330899924755526 1.0201047878001461 1.092984039091322 1.3201327284822328 1.040915276798126 1.2839896388763674 1.1314182603667071 1.0 15.21751146487232 -6.551584734167461 24.982486459135405 1.1704105294297442 1.0781353704375691 0.06667696697564929 0.11747690080530987 459.3575914529685 399770.4981670549 0.03858957070061722 0.038590175727047225 2.8081174341763876e-07 6.551584734167461 -0.09227515899217509 RADNCS(ph)PVAEEETTGSAESTLPK ddPTM_PC-9_Lapatinib_30min_R1 2 RADNCSPVAEEETTGSAESTLPK 23 1 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 RADNCS(1)PVAEEETTGSAESTLPK;RADNCS(1)PVAEEETTGSAESTLPK 104.42 1.2383e-06 23712000.0 86526.0 104267.0 122030.0 94850.0 122300.0 106054.0 106405.0 113742.0 122710.0 87251.0 True False 85292.12337307514 104025.57616764538 111997.16444942214 101825.58541032471 115106.5544510512 101518.31764394893 111914.1302563365 119026.86855558558 108889.10760641447 102332.21909535048 0.8334825935280674 1.0165476434232026 1.094446748438692 0.9950491283243482 1.1248319978656764 0.9920464790210093 1.093635330550761 1.1631416733441446 1.0640745267622356 1.0 16.642900920701692 -4.767383902462761 2.7960934655366745 1.0696153491480924 0.7847518580746777 0.6205088028450616 0.05435346963933191 0.29076910820212304 3.0253861185557427 0.013770648880855328 0.1962381380768675 1.7085043840277057e-05 4.767383902462761 -0.2848634910734147 RAEDGS(ph)VIDYELIDQDAR ddPTM_PC-9_AZD4547_30min_R2 2 RAEDGSVIDYELIDQDAR 18 1 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YN28;H0YNP5;H0YL33;H0YNA0 P07355 ANXA2 Annexin A2;Annexin 1 RAEDGS(1)VIDYELIDQDAR;RAEDGS(1)VIDYELIDQDAR 168.05 5.505100000000001e-25 3056000.0 6217.299999999999 9466.4 10954.599999999999 14588.7 13431.400000000001 12776.9 10000.3 12687.7 9571.8 9953.8 True False 8194.272072126341 12526.22867445846 10809.334846391515 11225.500608168164 11566.68195284015 11977.9584231896 10890.307326851891 10727.107499341308 10077.745806783005 9605.320491700924 0.8530972057836341 1.3040927354044276 1.1253486914602038 1.1686752792753858 1.2041953168386061 1.2470128855709348 1.1337786528061407 1.116788087249105 1.049183711828279 1.0 13.229618036405437 -8.262169204330467 1.6992498412906945 1.002641662253496 1.1599300362841678 0.1599570186208965 0.11238755020973516 0.5866696408919537 3.1856621856323932 0.09962994575941131 0.029801645345511107 5.468028829553178e-09 8.262169204330467 0.15728837403067186 RAEDGS(ph)VIDYELIDQDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RAEDGSVIDYELIDQDAR 18 1 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YN28;H0YNP5;H0YL33;H0YNA0 P07355 ANXA2 Annexin A2;Annexin 1 RAEDGS(0.991)VIDY(0.009)ELIDQDAR;RAEDGS(1)VIDYELIDQDAR 90.77799999999999 0.00059817 4236300.0 13208.2 15705.199999999999 20399.9 18836.5 23493.1 19744.3 18491.9 18406.7 19004.6 14304.6 True False 15444.087386158722 17264.308463949103 20886.310983051582 17781.151973756965 18889.795701629457 18708.874150146334 16740.21336223769 17923.543628510735 19282.506321829125 16897.9107448487 0.9139643130655561 1.0216830189620985 1.2360291931012086 1.0522692563740472 1.1178775877596572 1.1071708468959514 0.9906676402194227 1.0606958398081665 1.1411177756224902 1.0 14.044557262484526 -4.912391961462738 4.369948290570375 1.0896887289892783 0.9207613480021438 0.3829823358298311 0.06767709655907994 0.21609043718156254 7.160554458423705 0.016839608608912676 0.08174629212225602 1.2235114515997517e-05 4.912391961462738 -0.16892738098713445 RAEDGS(ph)VIDYELIDQDAR ddPTM_PC-9_Lapatinib_30min_R1 3 RAEDGSVIDYELIDQDAR 18 1 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YN28;H0YNP5;H0YL33;H0YNA0 P07355 ANXA2 Annexin A2;Annexin 1 RAEDGS(1)VIDYELIDQDAR;RAEDGS(0.988)VIDY(0.012)ELIDQDAR;RAEDGS(0.994)VIDY(0.006)ELIDQDAR 125.37 2.0336e-05 5358500.0 25260.5 23717.5 21393.7 20556.2 22338.600000000002 21006.100000000002 22386.4 20801.5 24251.9 17209.0 True False 24900.28063779164 23662.58358594887 19634.792568070166 22067.97152147298 21024.687467377396 20107.71807061077 23545.45825450355 21768.013629609242 21520.395638171325 20183.552720448868 1.2336916588804527 1.172369597844647 0.9728115183694728 1.0933640785209693 1.0416742661006522 0.9962427501793939 1.166566589173797 1.0785025773760377 1.0662342718469004 1.0 14.300892520349059 -5.063217810366177 5.675758829764936 1.0581488938807118 1.220547214732088 0.5706088080129883 0.05337405064918463 0.13355326845071266 8.595671751329332 0.013584764841750844 0.0390539720254769 8.645342228590125e-06 5.063217810366177 0.16239832085137618 RAEDGSVIDYELIDQDAR ddPTM_PC-9_AZD4547_30min_R2 6 RAEDGSVIDYELIDQDAR 18 1 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YN28;H0YNP5;H0YL33;H0YNA0 P07355 ANXA2 Annexin A2;Annexin 0 ;;;;; 219.23 5.7166e-28 220597400.0 263860.3 302269.2 419287.1 562915.1 449410.3 431271.8 332912.3 481760.0 343446.4 422906.5 False True 347762.38676481455 399971.8077036278 413727.0790966758 433143.7206465987 387017.4372314492 404304.3061692703 362540.84976341814 407315.0617434731 361600.27554427757 408100.6721577213 0.8521485272889052 0.9800812274796943 1.013786811252249 1.0613648792991914 0.9483381519202106 0.9906974767564612 0.8883613149828498 0.9980749592739103 0.8860565547035599 1.0 18.638565561209774 RAEDGSVIDYELIDQDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 RAEDGSVIDYELIDQDAR 18 1 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YN28;H0YNP5;H0YL33;H0YNA0 P07355 ANXA2 Annexin A2;Annexin 0 ;;;;; 216.16 1.0571000000000001e-27 208499500.0 228270.0 228887.0 291766.0 282560.0 346399.0 289334.0 262935.0 259488.0 254771.0 238593.9 False True 266911.6024619901 251609.38869851487 298722.8079687172 266729.07927187945 278524.6025960278 274160.8156966033 238027.8933154502 252676.7149502629 258496.5438956217 281849.085361727 0.9470018400784731 0.8927096157704316 1.059867934591075 0.9463542481592856 0.9882047416920564 0.9727220343636862 0.844522496888587 0.8964964872104372 0.9171452288513391 1.0 18.10456336018366 -7.207625709066474 24.992996119348728 0.9059156612971312 0.9685326581975316 0.18707265780426552 0.05318559689222504 451.52255648248064 209703.24573434627 0.019913714713433856 0.015425087085200295 6.199751622585391e-08 7.207625709066474 0.06261699690040046 RAEDGSVIDYELIDQDAR ddPTM_PC-9_Lapatinib_30min_R1 8 RAEDGSVIDYELIDQDAR 18 1 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YN28;H0YNP5;H0YL33;H0YNA0 P07355 ANXA2 Annexin A2;Annexin 0 ;;;;;;; 256.67 1.8594999999999997e-65 325943200.0 188647.2 167880.40000000002 178304.8 160364.4 184353.5 171615.4 140843.9 145536.2 187233.8 147935.40000000002 False True 185957.05633434057 167491.6832483408 163645.2676204321 172158.13293595574 173510.18958292645 164275.80939703668 148136.10798750457 152298.34315801944 166145.55778467853 173505.83677847 1.071762540022029 0.9653374569882165 0.9431686602530396 0.9922325158188483 1.0000250873661503 0.9468027845471383 0.8537816982874348 0.8777707193359264 0.9575790697854795 1.0 17.4046246706681 -6.967980564049499 5.162753543850328 0.9104033235362712 0.9891253423266549 0.31368070877380483 0.049193415781515114 0.20820079043600026 14.309804941801186 0.01784138837764224 0.015326960144351762 1.0765133896800721e-07 6.967980564049499 0.07872201879038376 RAELPGSS(ph)SPLLAQPR ddPTM_PC-9_AZD4547_30min_R2 1 RAELPGSSSPLLAQPR 16 1 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 RAELPGS(0.001)S(0.653)S(0.346)PLLAQPR 115.2 8.2666e-05 12765000.0 15823.0 21764.0 33213.0 44118.0 33116.0 28788.0 27894.0 35026.0 31123.0 25889.0 True False 20854.384861154365 28798.78738178338 32772.573919011294 33947.27671630527 28518.415023769223 26987.881809107243 30376.51196216181 29613.536517408866 32768.09824113619 24982.633989998325 0.8347552491664136 1.1527522435509736 1.311814195898304 1.3588349703196188 1.141529553496498 1.0802656685404632 1.215905095288307 1.1853648630190274 1.311635044337388 1.0 14.608637971946743 -4.7756397047511046 4.048257093244092 1.2084836615264811 0.800237639387713 0.5203867486882943 0.1044509879631627 0.18019941888113375 5.650079485886487 0.026474359548930758 0.21701194885807712 1.6763330027237735e-05 4.7756397047511046 -0.40824602213876815 RAELPGSSS(ph)PLLAQPR ddPTM_PC-9_AZD4547_30min_R2 1 RAELPGSSSPLLAQPR 16 1 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 RAELPGSS(0.004)S(0.995)PLLAQPR 158.92 2.3131999999999998e-05 9613400.0 17494.0 21244.0 32879.0 40889.0 40072.0 30086.0 24592.0 43442.0 29754.0 32195.0 True False 23056.728102195193 28110.707550937605 32443.00297724305 31462.672778752607 34508.694493069226 28204.717663915544 26780.640358983423 36729.0370978495 31326.735696005097 31067.862849395333 0.7421407843199598 0.9048162626186151 1.0442624629352155 1.0127079848160512 1.11075211900972 0.9078422227058495 0.8620045893985478 1.1822196227625084 1.008332496118728 1.0 14.923135381787292 -4.882245266963389 2.469402963743076 1.0162677017805046 0.7114897248310665 0.4939306444484992 0.08586522038517755 0.36633751534723513 3.3551058762428045 0.023373271835372397 0.2189625630542732 1.3114590458975312e-05 4.882245266963389 -0.3047779769494381 RAELPGSSS(ph)PLLAQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RAELPGSSSPLLAQPR 16 1 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 RAELPGSS(0.007)S(0.993)PLLAQPR;RAELPGSS(0.037)S(0.963)PLLAQPR 148.2 1.3892999999999999e-05 22324600.0 30636.0 28430.0 45248.0 41660.0 54931.0 43915.0 42602.0 44673.0 47874.0 35919.0 True False 35822.06971141858 31252.342512675616 46326.8839239956 39325.925263542355 44167.6648754829 41612.02009206081 38566.430148229745 43500.38108495604 48574.06668129018 42430.830365352434 0.8442462568601924 0.7365479827657394 1.0918212894986035 0.9268243144177202 1.0409333141768704 0.9807024687888212 0.9089247091360666 1.0252069240784165 1.1447823731716102 1.0 15.372825291792381 -5.256728676796401 24.99327879369053 1.0085777834303593 0.7903971070692545 0.6160095988754262 0.07075947493259097 252.03832143524104 1337212.4616181953 0.018048492240308668 0.04458896982667063 5.53695919809554e-06 5.256728676796401 -0.21818067636110483 RAELPGSSS(ph)PLLAQPR ddPTM_PC-9_Lapatinib_30min_R1 2 RAELPGSSSPLLAQPR 16 1 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 RAELPGSS(0.024)S(0.976)PLLAQPR;RAELPGSS(0.029)S(0.971)PLLAQPR 183.22 3.9332e-08 23968000.0 125081.0 95680.0 89098.0 97354.0 92445.0 79654.0 62269.0 59769.0 80932.0 67579.0 True False 123297.32200295405 95458.45883856162 81772.70636822614 104513.7379234236 87007.5668538629 76247.384102543 65492.984135442974 62546.08593746193 71816.58590825793 79259.94010664272 1.5556070549266108 1.2043720788852994 1.0317028533986088 1.3186199457481595 1.0977495912411224 0.961991442334597 0.8263062531629903 0.7891260812625821 0.9060893285010069 1.0 16.27430425667263 -6.6626737703471255 1.7349216654772135 0.8620749285030204 1.2613952047745758 0.6453906213231112 0.13310531772150294 0.23421165617596634 1.4528998621199412 0.0552104563914208 0.054291007549242806 2.1743338632809338e-07 6.6626737703471255 0.3993202762715554 RAELYEK ddPTM_PC-9_Lapatinib_30min_R1 1 RAELYEK 7 1 H0YB37;Q99614 H0YB37 TTC1 Tetratricopeptide repeat protein 1 0 112.41 0.0058051000000000005 3183900.0 28686.0 22426.0 25281.0 22634.0 24974.0 24813.0 20825.0 22554.0 28915.0 21573.0 False True 28276.93237963189 22374.073974849347 23202.493767482123 24298.579864810592 23505.07842077313 23751.805831928108 21903.216602492415 23601.941177425015 25658.288211551426 25301.864305784387 1.1175829590220099 0.8842855887790962 0.9170270414491822 0.9603474104181158 0.9289860279346892 0.9387373809643776 0.865675996747995 0.9328143132926872 1.014086863381271 1.0 14.626956069829438 -8.260354395162885 24.74301830717737 1.007043438050127 0.9377143188542036 0.13144260304105815 0.06444963710972672 150.75667502263948 3438260.1270024423 0.047853124189746854 0.0157713337813902 5.490926176745496e-09 8.260354395162885 -0.06932911919592333 RAETFAGYDCTNS(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 2 RAETFAGYDCTNSPTK 16 1 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 RAETFAGYDCT(0.205)NS(0.787)PT(0.007)K;RAETFAGYDCT(0.001)NS(0.995)PT(0.003)K 246.49 7.6134e-47 80688000.0 184486.0 203829.0 195353.0 237419.0 248221.0 260111.0 201608.0 220982.0 202767.0 230437.0 True False 243148.71045281691 269712.7381566587 192762.49157861725 182685.71763698474 213759.79875634218 243846.21805087835 219550.7214335526 186834.30956118484 213484.8496629653 222369.47076956433 1.0934446604173715 1.2129036293662585 0.8668568167721727 0.8215413608925534 0.9612821311152728 1.0965813661695036 0.987324027321481 0.8401976625415292 0.960045679490752 1.0 17.76259920767516 -5.259322062888732 24.99942312303832 0.9395862015756721 1.1531741546356595 0.5136314113235484 0.08228182113768502 151.38748070408093 1787419.0892689822 0.02295859652820175 0.05497735367124112 5.50399381389796e-06 5.259322062888732 0.21358795305998746 RAETFAGYDCTNS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RAETFAGYDCTNSPTK 16 1 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 RAETFAGYDCTNS(1)PTK;RAETFAGYDCT(0.068)NS(0.905)PT(0.026)K;RAETFAGYDCTNS(0.998)PT(0.002)K 162.81 1.4027e-05 62868700.0 206133.0 214561.0 213270.0 246934.0 250032.0 213905.0 238719.0 194819.0 210335.0 160185.0 True False 241027.24558766972 235861.19809575073 218355.1656309787 233099.08855082962 201040.02446973027 202687.44524176864 216105.80814410723 189705.20767779349 213410.75146027474 189225.27247623756 1.2737582165085128 1.2464571724972393 1.1539429314781364 1.2318602346317225 1.0624374949438975 1.0711436299674064 1.1420557376723834 1.002536316609697 1.127813154487989 1.0 17.529745258892362 -1.522878745280381 0.21045121127216868 1.007645655683418 2.447258477831429 0.7027094565623417 0.05070733928954991 27.09854091840359 0.33775622060869653 0.08199135618667641 13.065266263437112 0.029999999999997005 1.522878745280381 1.439612822148011 RAETFAGYDCTNS(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 2 RAETFAGYDCTNSPTK 16 1 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 RAETFAGYDCTNS(0.989)PT(0.011)K;RAETFAGYDCTNS(0.99)PT(0.01)K 132.52 2.895e-06 124405000.0 221690.0 288176.0 298370.0 276858.0 304482.0 252752.0 287489.0 266399.0 268908.0 237065.0 True False 218528.6599470332 287508.7461774814 273839.1703415072 297219.0608912134 286572.96739464405 241942.38615368944 302373.7737255194 278776.8700773637 238620.74931322402 278041.36938074284 0.7859573574743316 1.0340502451769116 0.9848864251798398 1.0689742377301024 1.030684635286119 0.8701668629116109 1.0875136113700274 1.0026452923112088 0.8582203067287544 1.0 18.084940029904004 -4.754970725714355 24.98071824129953 0.9955092506873219 0.7859570030908314 0.42878911050768886 0.07164323939929279 207.626201218317 801738.1764424635 0.017520448996845964 0.1618886098078387 1.7580421134898538e-05 4.754970725714355 -0.2095522475964905 RAFS(ph)EQGPLR ddPTM_PC-9_AZD4547_30min_R2 2 RAFSEQGPLR 10 1 J3KNG8;Q8TF40;Q8TF40-2 J3KNG8 FNIP1 Folliculin-interacting protein 1 1 RAFS(1)EQGPLR;RAFS(1)EQGPLR 89.189 0.0043589 5848500.0 12693.3 14424.2 15357.0 26286.0 21166.3 18002.0 14983.5 21038.9 13369.2 18454.6 True False 16729.505362958396 19086.540569395318 15153.356145914457 20226.168814651643 18227.724601932812 16876.332094190246 16317.002473114357 17787.821430826058 14075.868618237251 17808.510071143064 0.9394107253288365 1.071765155711885 0.8509053303942017 1.135758619550445 1.023540123745054 0.9476554763296385 0.9162474798806696 0.9988382722510554 0.7904012498522158 1.0 14.120279199588703 -6.890551661006051 4.7568081259401955 0.9270250434939742 1.0065116959239169 0.14859531014162175 0.0890451534470732 0.41262435311089224 15.489991385677026 0.030863422548178518 0.027144994001161042 1.2866141961984167e-07 6.890551661006051 0.07948665242994268 RAFS(ph)EQGPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RAFSEQGPLR 10 1 J3KNG8;Q8TF40;Q8TF40-2 J3KNG8 FNIP1 Folliculin-interacting protein 1 1 RAFS(1)EQGPLR 87.21600000000001 0.004936600000000001 1848500.0 6813.8 6689.3 7210.6 7085.1 8728.3 7765.7 6375.4 6678.3 8464.6 6649.9 True False 7967.241761315577 7353.3694959564145 7382.52805035278 6688.14481720412 7018.052271625811 7358.45302126646 5771.475958101123 6503.001701243747 8588.37876155009 7855.474229420563 1.0142279802123746 0.9360821869183085 0.9397940639539635 0.8513992436198792 0.8933963840580861 0.9367293184805262 0.7347075160001945 0.8278305690175275 1.0932985725272486 1.0 12.939482657289323 -4.688254511244961 1.24776015422501 0.8932952332979456 1.084154077352415 0.08964174388874846 0.09270683020983835 3.7793247555618534 4.394956636154528 0.027915869982884374 0.9849460290733364 2.0499604806145454e-05 4.688254511244961 0.1908588440544694 RAFS(ph)EQGPLR ddPTM_PC-9_Lapatinib_30min_R1 1 RAFSEQGPLR 10 1 J3KNG8;Q8TF40;Q8TF40-2 J3KNG8 FNIP1 Folliculin-interacting protein 1 1 RAFS(1)EQGPLR 84.169 0.0058291 3135800.0 14579.0 9006.4 10107.0 8428.6 7796.7 8134.6 8343.3 8793.1 9876.7 7721.1 True False 14371.100786538835 8985.54623415157 9276.041474148242 9048.467360985353 7338.113434901972 7786.702120678772 8775.275249919567 9201.659526789756 8764.282039738195 9055.681847280952 1.5869705924854112 0.9922550709806087 1.0243338525561667 0.999203319372603 0.8103325137361473 0.8598692237643926 0.9690352861230898 1.0161200097320817 0.9678213289228738 1.0 13.144607557605195 -4.756562190057058 4.590034904962894 0.9529208986236605 1.6410115105593661 0.8919860837805947 0.06556202690745776 0.0687399106423406 3.2671492095598578 0.018442434644546035 0.15705073740806935 1.7516115891505224e-05 4.756562190057058 0.6880906119357056 RAFS(ph)WLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RAFSWLR 7 1 Q9P206-2 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 RAFS(1)WLR 72.325 0.017941 1933900.0 6493.7 4568.7 5645.4 5228.5 7284.8 7577.3 7382.7 9096.3 5882.4 4186.4 True False 7592.955153578758 5022.250342513579 5780.007746298727 4935.564096025711 5857.39573437436 7179.933048925706 6683.357209880657 8857.531763326524 5968.418971592543 4945.361180475833 1.5353691826505134 1.015547734378088 1.168773631563668 0.9980189344938443 1.184422233405159 1.4518521068333512 1.3514396554626567 1.7910788393567383 1.206872208880459 1.0 12.27186017556615 -6.722169813657164 7.0469906203915995 1.4091212618157796 1.159234808865088 0.10864750679025992 0.23409865755672404 0.31422357525034816 42.68841274893888 0.0748526038918999 0.07386693202418579 1.8959644344525713e-07 6.722169813657164 -0.24988645295069167 RAGDLLEDS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 RAGDLLEDSPK 11 1 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 RAGDLLEDS(1)PK;RAGDLLEDS(1)PK;RAGDLLEDS(1)PK;RAGDLLEDS(1)PK 141.34 3.1434e-05 201856000.0 425408.0 498645.0 301680.0 264724.0 294310.0 373555.0 450172.0 349621.0 391727.0 331795.0 True False 560678.8949639109 659822.2447155571 297679.52608578996 203695.97174502938 253450.13666039202 350196.5467973137 490236.435901281 295595.1079413302 412432.8894934794 320178.9580405375 1.7511422311922322 2.0607920294125566 0.9297285740061066 0.6361941240349707 0.7915889857705858 1.093752534334176 1.5311325856685833 0.9232184080751029 1.2881323995103442 1.0 18.288518972396943 -5.263980622572241 24.985058097428844 1.0198974636293703 1.9059671752633993 0.6731524253463161 0.24575062897045416 124.47289002519352 1223809.246308009 0.06942911920794226 0.15610233100158144 5.445269480997817e-06 5.263980622572241 0.886069711634029 RAGDLLEDS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 RAGDLLEDSPK 11 1 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 RAGDLLEDS(1)PK;RAGDLLEDS(1)PK;RAGDLLEDS(1)PK;RAGDLLEDS(1)PK;RAGDLLEDS(1)PK;RAGDLLEDS(1)PK;RAGDLLEDS(1)PK;RAGDLLEDS(1)PK 123.1 0.00027702 114435600.0 530363.0 733702.0 421622.0 497538.0 458852.0 333068.0 498509.0 346206.0 314157.0 351500.0 True False 620142.9807532679 806539.085692406 431675.0674903392 469662.55889996036 368943.2444966431 315601.327747296 451286.618627385 337118.4593355791 318750.9517983467 415224.16752753075 1.4935136951346897 1.9424184543375111 1.0396193219213756 1.1311060280922116 0.8885399101250071 0.760074563160803 1.0868505590958002 0.811895081500108 0.7676599213778 1.0 18.66353089057342 -5.3643616717657965 4.853783366098636 0.924089657085513 1.7137309223380146 0.7995351384247991 0.15718004399585345 0.08509272440880807 3.129241317556661 0.04162681934753253 0.09055228067965203 4.3215379209709585e-06 5.3643616717657965 0.7896412652525016 RAGDLLEDS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 RAGDLLEDSPK 11 1 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 RAGDLLEDS(1)PK;RAGDLLEDS(1)PK;RAGDLLEDS(1)PK;RAGDLLEDS(1)PK 120.92 0.00037528 509820000.0 586086.0 776147.0 401812.0 539649.0 583887.0 482772.0 682004.0 648673.0 406012.0 534791.0 True False 577728.306164992 774349.8793078304 368776.56839917327 579336.5876762908 549543.9146260092 462124.9669564986 717314.8300487984 678812.7156772104 360282.65306409914 627228.9117857849 0.9210804784494714 1.2345570568537363 0.5879457427260945 0.9236445846012746 0.8761457010350518 0.7367724259406053 1.1436252643497087 1.0822407942653043 0.5744037723617325 1.0 19.258632535689422 -5.234307258142075 24.99857185873648 0.8763129194656384 1.0778187003775834 0.15970709425068985 0.19347123202667216 1424.677594842055 1312642.769600881 0.04827304593146124 0.12765042698094256 5.830324698376898e-06 5.234307258142075 0.20150578091194504 RAGDLLEDS(ph)PKRPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RAGDLLEDSPKRPK 14 3 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 RAGDLLEDS(1)PKRPK 75.998 0.013884 92417000.0 157830.0 110600.0 121000.0 193960.0 160450.0 183220.0 188500.0 178190.0 167620.0 135790.0 True False 184547.50171540648 121579.63707006401 123885.09889505555 183093.0500268047 129010.97429996217 173611.6206596237 170643.91537818234 173512.70130791084 170071.1253941147 160407.65208695157 1.1504906362906522 0.7579416286459938 0.7723141463843733 1.141423414935069 0.8042694511233771 1.0823150791180132 1.0638140584819609 1.0816984043495348 1.0602432189576898 1.0 17.291383440198324 -6.789523329720178 24.998625304283397 1.0631078661309643 0.9194997911900118 0.20516802722379934 0.12975184802498752 330.4619517538743 294154.84141081746 0.044931747230205786 0.03963394231252824 1.6235911309902706e-07 6.789523329720178 -0.1436080749409525 RAGELTEDEVER ddPTM_PC-9_AZD4547_30min_R2 2 RAGELTEDEVER 12 1 P62269 P62269 RPS18 40S ribosomal protein S18 0 ; 124.12 0.00020994 21759000.0 45671.0 56460.0 84531.0 128338.0 86976.0 85969.0 61963.0 93922.0 58931.0 73358.0 False True 60193.427984186426 74709.5908645235 83410.06370842576 98751.65690233429 74900.88371504284 80593.34483976456 67477.58696176352 79408.51301284971 62045.97234997903 70789.75874843728 0.8503126588987737 1.0553728701070444 1.1782786830060652 1.3949992011311139 1.0580751374109794 1.138488762564736 0.9532111445888085 1.1217514286923982 0.8764823252254511 1.0 16.11125303828215 -7.252644406348593 23.805326185307408 0.9980071763739908 1.1233321820733344 0.15836131572651735 0.13876599446306595 679.4168020074169 1838978.2640584847 0.05641049872219571 0.04296118126133543 5.589276488073044e-08 7.252644406348593 0.12532500569934357 RAGELTEDEVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RAGELTEDEVER 12 1 P62269 P62269 RPS18 40S ribosomal protein S18 0 139.46 4.5875e-05 7287600.0 16927.0 13086.0 18928.0 14988.0 23429.0 12798.0 26038.0 29574.0 15671.0 14997.0 False True 19792.406776510707 14385.091597638859 19379.315304839747 14148.270951751616 18838.25563648376 12126.850350408618 23571.492141204802 28797.71383624316 15900.158728380715 17715.837383813316 1.117215424126365 0.8119904967507938 1.093897786764871 0.7986227602584945 1.0633567710265832 0.6845203016758741 1.3305322029395972 1.6255350064657503 0.897510988834682 1.0 14.112752039243476 -7.282549322706845 24.936776492974023 1.2655224972133776 0.930758097803543 0.2649937395226293 0.22603801407493515 902.8341727033113 1066496.3337914008 0.0894755615780341 0.06039361249763836 5.217358474750964e-08 7.282549322706845 -0.3347643994098346 RAGELTEDEVER ddPTM_PC-9_Lapatinib_30min_R1 1 RAGELTEDEVER 12 1 P62269 P62269 RPS18 40S ribosomal protein S18 0 139.89 4.6678e-05 9563700.0 30039.0 29167.0 35658.0 23876.0 27368.0 24015.0 24167.0 21020.0 31839.0 21956.0 False True 29610.63835152208 29099.465603515124 32726.336883860477 25631.920688001133 25758.268047558224 22987.93443169926 25418.249009960844 21996.665937282705 28252.956540466395 25751.065345468982 1.1498801293955867 1.1300295818104982 1.270873124851855 0.995373214433289 1.0002797050138552 0.8926983844473872 0.9870756284820388 0.8542041131961602 1.0971568034732837 1.0 14.652344498712552 -5.868752821445731 6.356150567326287 0.9648537448989322 1.177246147251397 0.6454964521829232 0.07067150410339744 0.12184865849338603 6.408331635372998 0.019162731457447586 0.028729379966960886 1.352842313857183e-06 5.868752821445731 0.21239240235246493 RAGGFIS(ph)FNGSWR ddPTM_PC-9_Lapatinib_30min_R1 1 RAGGFISFNGSWR 13 1 Q5SGD2-2;Q5SGD2-3;Q5SGD2 Q5SGD2-2 PPM1L Protein phosphatase 1L 1 RAGGFIS(0.5)FNGS(0.5)WR 67.095 0.016467 1305000.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RALASNTSFFSGCS(ph)PIEEEAH ddPTM_PC-9_Lapatinib_30min_R1 2 RALASNTSFFSGCSPIEEEAH 21 1 O95239;Q2VIQ3 O95239 KIF4A;KIF4B Chromosome-associated kinesin KIF4A;Chromosome-associated kinesin KIF4B 1 RALASNTSFFS(0.005)GCS(0.995)PIEEEAH;RALASNTSFFS(0.023)GCS(0.977)PIEEEAH 102.29 6.6212e-05 6633400.0 13208.900000000001 20246.9 23265.0 18292.9 21316.8 22375.0 15797.7 20159.7 22086.0 17759.3 True False 13020.538663784411 20200.019547015825 21352.24150549707 19638.220889325516 20062.9877344413 21418.07340867252 16615.627607260238 21096.393258603148 19598.442104109454 20828.97134222022 0.6251167400375575 0.9698039915235991 1.0251222278181442 0.9428320086800899 0.9632250870581269 1.028282820921559 0.7977171476337118 1.012838940146836 0.9409222271281114 1.0 14.346303971874606 -4.760727292455894 24.999594156052712 0.9628828826548145 0.6251163506716227 0.7203708264084286 0.06343203274652605 9.008621324119936 316052.11525693885 0.0152841590080084 0.08896712922501356 1.734893051221091e-05 4.760727292455894 -0.33776653198319173 RALELEQER ddPTM_PC-9_AZD4547_30min_R2 1 RALELEQER 9 1 P26038 P26038 MSN Moesin 0 107.21 0.0028416 0.0 19582.0 19148.0 23437.0 31168.0 27598.0 27254.0 17864.0 28795.0 22968.0 27551.0 False True 25808.66866909721 25337.216540451573 23126.21006653623 23982.699140799738 23766.49407615603 25549.80307160654 19453.861392846437 24345.394393273236 24182.04158989866 26586.44787587173 0.9707452755476828 0.9530124768358437 0.8698495629995083 0.9020648133504514 0.8939326602454883 0.9610085255049815 0.7317209686556735 0.9157069235776947 0.9095627104004682 1.0 14.698403416083448 -5.1518104207585695 4.990677367693663 0.8913997227816063 0.96614473735292 0.1254784775985912 0.06611611110684186 0.40100874610226755 14.869803675277232 0.016488582888962225 0.0468961552777347 7.050007503812721e-06 5.1518104207585695 0.07474501457131366 RALELEQER ddPTM_PC-9_Lapatinib_30min_R1 2 RALELEQER 9 1 P26038 P26038 MSN Moesin 0 ; 133.23 0.00074426 5673700.0 48822.0 48332.0 54576.0 42309.0 51369.0 47577.0 44902.0 41742.0 48905.0 34496.0 False True 48125.7893271417 48220.09022350924 50088.971949452316 45420.544998686535 48347.576415339776 45542.24261740394 47226.805852826656 43681.485706662934 43396.80390751939 40458.58763696929 1.1895073985026223 1.1918381990044513 1.2380306598662183 1.1226428714279493 1.194989228224118 1.1256508266193017 1.1672875552796822 1.0796591838205616 1.072622808707867 1.0 15.304158337490499 -8.050131027928328 0.48204398256556164 0.9941447547081732 1.201238998193643 0.7998322244799871 0.03059808516429822 0.37119837830175056 0.22039180689325147 0.03199005647234568 0.019802420511242157 8.90982085651312e-09 8.050131027928328 0.2070942434854699 RALLETAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 RALLETASPR 10 1 Q96BT3;H3BMP6;H3BQS6;H3BN05;H3BTS2;H3BQJ0;I3L4F8;H3BUW2;H3BTR4;Q96BT3-3;Q96BT3-2 Q96BT3 CENPT Centromere protein T 1 RALLET(0.001)AS(0.999)PR;RALLET(0.002)AS(0.998)PR 110.15 0.00081648 14527000.0 48672.0 37251.0 62539.0 92011.0 81461.0 60208.0 52024.0 77621.0 50158.0 65592.0 True False 64148.683559508696 49291.657266991926 61709.69199774331 70799.28550577925 70151.54626921333 56443.184242140116 56654.03521615783 65626.45800313463 52809.24948041349 63295.644044651 1.0134770650924403 0.778752756385887 0.9749437410607766 1.1185490972464853 1.108315545691042 0.8917388407063697 0.8950700489940833 1.036824239545448 0.8343267578280736 1.0 15.949818597506129 -10.391242520817993 14.840567105245961 1.000001834923444 0.9635348854952355 0.01132457901314865 0.1066151206434556 0.0 0.0 0.10762327803966037 0.026102479007808085 4.062164244826808e-11 10.391242520817993 -0.036466949428208606 RALLETAS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RALLETASPR 10 1 Q96BT3;H3BMP6;H3BQS6;H3BN05;H3BTS2;H3BQJ0;I3L4F8;H3BUW2;H3BTR4;Q96BT3-3;Q96BT3-2 Q96BT3 CENPT Centromere protein T 1 RALLET(0.002)AS(0.998)PR;RALLET(0.003)AS(0.997)PR 96.37100000000001 0.0025474 9939100.0 35980.0 29072.0 43900.0 49143.0 53127.0 51588.0 45694.0 51997.0 45503.0 40367.0 True False 42070.70336260739 31958.076029845415 44946.742491677134 46389.67703375565 42717.14572536056 48882.63446451631 41365.53352408833 50632.13384537547 46168.395291781475 47685.217555003845 0.8822588114247306 0.6701883239388072 0.9425718240633392 0.972831401686407 0.895815263421778 1.0251108618332563 0.867470793781618 1.0617993676336366 0.9681909333542885 1.0 15.541254478791355 -5.389103402800487 6.594323152798785 0.9668191727066576 0.7775170289336916 0.5340180939505688 0.07146739548644915 0.160000784770813 7.806817562887437 0.017467995677799535 0.036744737954478024 4.082221796126531e-06 5.389103402800487 -0.18930214377296606 RALLETAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 RALLETASPR 10 1 Q96BT3;H3BMP6;H3BQS6;H3BN05;H3BTS2;H3BQJ0;I3L4F8;H3BUW2;H3BTR4;Q96BT3-3;Q96BT3-2 Q96BT3 CENPT Centromere protein T 1 RALLETAS(1)PR;RALLET(0.167)AS(0.833)PR 106.79 0.0010389000000000002 15369000.0 72005.0 57542.0 65425.0 60572.0 51219.0 52080.0 42455.0 43002.0 57734.0 39688.0 True False 70978.19549590009 57408.76503436997 60046.009047803345 65026.66694226859 48206.399120428425 49852.659804409624 44653.112166089595 45000.029906519085 51231.38895402764 46548.01791906416 1.5248381922365448 1.2333235141008592 1.2899799332424629 1.3969803624148802 1.0356273215381113 1.0709942556757508 0.9592913761383063 0.9667442765181398 1.1006137585301 1.0 15.506432116630672 -6.268923580598056 23.629729067067977 1.0198421049800541 1.3470478228039424 0.8051695302868527 0.08158547382853239 117.38580715809316 370619.3209316701 0.02491362596820964 0.028844744195392888 5.38364505971979e-07 6.268923580598056 0.3272057178238883 RALLSLRS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RALLSLRSPK 10 2 Q5H909;Q9UNF1-2;Q9UNF1 Q5H909 MAGED2 Melanoma-associated antigen D2 1 RALLS(0.003)LRS(0.997)PK 51.268 0.035588 5187800.0 16773.0 10005.0 9002.3 17630.0 18457.0 18651.0 19040.0 15962.0 17851.0 16218.0 True False 19612.33761814937 10998.230279258501 9216.94897341287 16642.248257231182 14840.48334468312 17672.908726790978 17236.39336233733 15543.01441313699 18112.037104225914 19158.19501838265 1.023704874041159 0.5740744505787467 0.48109693865048525 0.8686751670114347 0.7746284725906275 0.9224725351127019 0.8996877495922078 0.8112984755726297 0.9453937120301299 1.0 14.22567402409465 -5.949444814595305 24.98569368212094 0.8789640527070327 0.6800389832255952 0.2787546722978982 0.14344415890218093 134.7744304294478 66608.03597503153 0.04020634995839848 0.05963564343533254 1.1234537168464395e-06 5.949444814595305 -0.1989250694814375 RALLSLRS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 RALLSLRSPK 10 2 Q5H909;Q9UNF1-2;Q9UNF1 Q5H909 MAGED2 Melanoma-associated antigen D2 1 RALLS(0.003)LRS(0.997)PK 51.445 0.035278 5913100.0 42206.0 25007.0 27709.0 28390.0 26195.0 25886.0 19885.0 17837.0 23903.0 20891.0 True False 41604.13470036752 24949.09782792551 25430.872979833144 30477.89530626372 24654.261601351496 24778.916123213265 20914.548001947755 18665.77213716991 21210.79243025122 24501.981514492287 1.6979906166266492 1.0182481695681946 1.0379108712000065 1.2438951228592199 1.0062150110908026 1.011302539288799 0.8535859840387743 0.7618066369909549 0.8656766154894691 1.0 14.58061080655418 -2.162063557400263 1.0353839433207956 0.9495901176979864 199.99999999999292 0.7379656738394449 0.12747715276329216 261.39546668966267 1.3536840274903708 0.044614809333485356 122221.0143046979 0.006885515219874551 2.162063557400263 199.05040988229493 RALPNNT(ph)SSSPQPK ddPTM_PC-9_AZD4547_30min_R2 2 RALPNNTSSSPQPK 14 1 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;A0A087X1Q1;A0A087WXZ1;A0A087WT22 J3KP33 TP53 Cellular tumor antigen p53 1 RALPNNT(0.934)S(0.003)S(0.011)S(0.052)PQPK;RALPNNT(0.744)S(0.035)S(0.11)S(0.11)PQPK 117.7 0.00043044 60293900.0 25855.0 21251.4 29287.0 44437.0 41305.0 29679.0 26205.0 31832.0 31717.0 33507.0 True False 34076.35218259155 28120.499456222726 28898.635244214154 34192.73619480616 35570.513726198486 27823.16743825532 28537.194234188366 26913.09582659052 33393.49586846117 32333.930128737044 1.0538883472227807 0.8696901163657307 0.8937557274712565 1.0574877863182208 1.1000986760525255 0.8604944504883202 0.8825773458582971 0.8323484253054437 1.03276946957903 1.0 14.98076125455559 -6.805743512687606 24.999998912030378 0.9087184679061041 0.985872917637805 0.1362331187330753 0.08794811180874998 274.2257848572488 154738.54450479362 0.032276359176115446 0.02846520808613672 1.5640710850709742e-07 6.805743512687606 0.07715444973170094 RALPNNTSS(ph)SPQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RALPNNTSSSPQPK 14 1 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;A0A087X1Q1;A0A087WXZ1;A0A087WT22 J3KP33 TP53 Cellular tumor antigen p53 1 RALPNNTSS(0.982)S(0.018)PQPK;RALPNNTS(0.006)S(0.497)S(0.497)PQPK 144.41 8.0343e-05 293520000.0 127704.0 85932.0 120091.0 153946.0 146984.0 159278.0 151673.0 153569.0 145725.0 118950.0 True False 149321.7649310291 94462.76105519637 122954.42488765382 145320.90471966597 118183.54033347238 150925.181287106 137305.4354225731 149537.97646980506 147855.95244038515 140514.6933923184 1.0626772284526946 0.6722625141518503 0.8750289519144012 1.034204332737848 0.8410760289922333 1.074088251153361 0.9771606947838185 1.0642159396974489 1.0522454902817164 1.0 17.10036147303866 -6.436054726400091 0.9418573349829952 1.0389216827247079 0.8619216660703662 0.23719818876383747 0.10845640610862435 0.7328113197896389 1.4074137608211998 0.05453701464227084 0.07122947293568285 3.663914019546612e-07 6.436054726400091 -0.17700001665434162 RALPNNTSS(ph)SPQPK ddPTM_PC-9_Lapatinib_30min_R1 1 RALPNNTSSSPQPK 14 1 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;A0A087X1Q1;A0A087WXZ1;A0A087WT22 J3KP33 TP53 Cellular tumor antigen p53 1 RALPNNT(0.015)SS(0.493)S(0.493)PQPK 188.63 5.0938e-06 40692000.0 149390.0 76160.0 106450.0 91151.0 73938.0 90168.0 62085.0 60161.0 84153.0 60062.0 True False 147259.67120522898 75983.65619925657 97698.09190888295 97854.54861082231 69589.11220770095 86311.72483187413 65299.45751576191 62956.29968852831 74674.80296962432 70443.6366724156 2.0904609438327464 1.078644712120752 1.3868973341511157 1.3891183538106617 0.9878693874268808 1.2252593549826223 0.9269745373797823 0.8937116631455913 1.0600645636295716 1.0 16.10418177017553 -1.5228787453881154 0.7797598976930942 1.0529692829186534 199.99999825829673 0.7097688296646931 0.18283288673955755 258.340271351833 0.9817739091914782 0.06799643998773777 90599.27930321539 0.02999999999255497 1.5228787453881154 198.94702897537806 up RALPNNTSSS(ph)PQPK ddPTM_PC-9_AZD4547_30min_R2 5 RALPNNTSSSPQPK 14 1 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;A0A087X1Q1;A0A087WXZ1;A0A087WT22 J3KP33 TP53 Cellular tumor antigen p53 1 RALPNNT(0.07)S(0.003)S(0.019)S(0.908)PQPK;RALPNNTSS(0.044)S(0.956)PQPK;RALPNNTSS(0.018)S(0.982)PQPK;RALPNNT(0.003)SS(0.091)S(0.906)PQPK;RALPNNTSS(0.009)S(0.991)PQPK 164.22 8.8763e-06 412373000.0 254795.5 205370.9 294379.0 468472.0 377241.0 304517.7 261109.2 314847.0 250184.7 302438.0 True False 335815.16892436746 271753.0271781607 290475.34211617836 360473.0182202498 324867.59880365175 285476.1600799352 284347.4129644543 266194.6306143049 263408.9524798121 291849.73767496226 1.1506440663598272 0.9311402139439864 0.99529074252479 1.2351322330867207 1.1131330848255276 0.9781614414122742 0.9742938788628845 0.9120948085647078 0.9025499031737176 1.0 18.15486624591137 -6.902681907198424 4.358417178920072 0.94405174280851 1.079451037011311 0.396467627817762 0.08155394883939619 0.2552765349481814 8.703480762590349 0.032060320736957394 0.02805907003827942 1.251175100059776e-07 6.902681907198424 0.13539929420280106 RALPNNTSSS(ph)PQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RALPNNTSSSPQPK 14 1 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;A0A087X1Q1;A0A087WXZ1;A0A087WT22 J3KP33 TP53 Cellular tumor antigen p53 1 RALPNNTS(0.001)S(0.065)S(0.934)PQPK;RALPNNT(0.029)S(0.001)S(0.029)S(0.94)PQPK;RALPNNTSS(0.107)S(0.893)PQPK;RALPNNT(0.006)S(0.006)S(0.136)S(0.852)PQPK 154.23 0.00042423 240713300.0 214840.0 177371.0 201376.0 283455.0 286694.0 269656.0 251486.0 256448.0 254329.0 191122.0 True False 251208.16871658122 194979.22067589845 206177.56756273258 267573.93532350904 230518.3687500993 255514.76465774223 227663.42547903166 249716.5117291166 258048.08048180377 225770.90567908075 1.1126684723214866 0.8636153541991334 0.9132158412643351 1.1851568496777378 1.0210277894609094 1.1317435428147704 1.008382478664638 1.1060615227547212 1.1429642792353547 1.0 17.78450005737266 -5.744580134088458 24.999447938454242 1.0855510439205185 0.9532114113465163 0.3115846760988118 0.08262138728299663 264.47466903865444 392168.62990466214 0.021380344918506895 0.03690642978955462 1.8006108630709632e-06 5.744580134088458 -0.13233963257400216 RALPNNTSSS(ph)PQPK ddPTM_PC-9_Lapatinib_30min_R1 5 RALPNNTSSSPQPK 14 1 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;A0A087X1Q1;A0A087WXZ1;A0A087WT22 J3KP33 TP53 Cellular tumor antigen p53 1 RALPNNTSS(0.052)S(0.948)PQPK;RALPNNTSS(0.054)S(0.946)PQPK;RALPNNT(0.001)S(0.005)S(0.227)S(0.768)PQPK;RALPNNTS(0.003)S(0.251)S(0.746)PQPK;RALPNNTS(0.009)S(0.124)S(0.867)PQPK 116.04 6.8905e-05 647859000.0 286816.0 179707.0 212385.0 201067.0 196014.0 193274.0 157328.0 137920.0 187045.0 151376.0 True False 282725.95124438766 179290.89948266474 194923.52512980814 215854.1379198494 184484.8418983515 185008.12156369942 165473.6740281837 144328.26670171428 165978.0224288304 177541.13990415886 1.5924531711185936 1.0098555161888136 1.0979062387175882 1.2157978597882881 1.039110383080457 1.0420577544087608 0.9320300304341322 0.8129285797062376 0.9348707714641771 1.0 17.437793839666007 -2.5747463123519503 1.2999952399079924 0.9979040488220131 199.99999999999991 0.7257773285091466 0.10584905198134342 295.81765769622035 1.9479161171463086 0.03465996701468548 174045.19536544365 0.002662279742838556 2.5747463123519503 199.0020959511779 RALS(ph)PLPTR ddPTM_PC-9_AZD4547_30min_R2 2 RALSPLPTR 9 1 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 RALS(1)PLPTR;RALS(1)PLPTR 79.283 0.0093384 32174000.0 32499.0 33207.0 52156.0 63399.0 53082.0 39638.0 54814.0 62498.0 48648.0 43223.0 True False 42833.00597880654 43940.5133517221 51464.37736187498 48783.34005478576 45712.480562015895 37159.42959390695 59692.33981121164 52840.37016116654 51219.433963139636 41709.77592605731 1.026929659242008 1.0534823641733155 1.2338684689438402 1.1695900774261747 1.0959656230964785 0.8909045605946873 1.4311354709033597 1.2668581642548606 1.2279959032611674 1.0 15.348097941327433 -7.265905668513923 24.99962995697165 1.2537355489627637 1.089324038276794 0.240950416674362 0.12985185541404654 540.1794949821999 3023585.41131513 0.053006095066946875 0.03718132184807828 5.421186291816755e-08 7.265905668513923 -0.16441151068596982 RALS(ph)PLPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RALSPLPTR 9 1 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 RALS(0.991)PLPT(0.009)R;RALS(0.997)PLPT(0.003)R 56.956 0.038773 6150800.0 8079.9 13976.0 12619.5 14787.400000000001 17803.9 14816.8 19462.9 13364.1 17785.0 8284.5 True False 9447.667484700713 15363.444915833777 12920.396739720261 13958.909919397647 14315.353601365527 14039.780924514327 17619.233212806463 13013.306535434402 18045.071979085646 9786.414269934077 0.965386016176112 1.5698747766108279 1.3202380752891727 1.4263559189684372 1.4627782154435567 1.4346195181668824 1.8003768006159777 1.3297318278681514 1.8438900583356563 1.0 13.256564639631016 -4.7551908103628495 24.75695927161371 1.479303008184691 0.9653850475684089 0.29762266802513493 0.22949794450694627 215.77115166742792 854797.123163112 0.052520087300322905 0.4736022618373522 1.7571514273880112e-05 4.7551908103628495 -0.513917960616282 RALS(ph)PLPTR ddPTM_PC-9_Lapatinib_30min_R1 1 RALSPLPTR 9 1 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 RALS(1)PLPTR 60.157 0.032639 13545000.0 21829.0 16773.0 14309.0 16223.0 15077.0 13401.0 15157.0 11618.0 21797.0 12239.0 True False 21517.714457051676 16734.163149030057 13132.569254337315 17416.093538341534 14190.200502522488 12827.870469256784 15941.755296229427 12157.814693594219 19341.99232741437 14354.494842557604 1.499022758589655 1.1657786172605191 0.9148750547042885 1.2132850183419226 0.9885545021376843 0.8936483387228126 1.1105758489644637 0.8469691777344361 1.3474519681507733 1.0 13.809214940261004 -4.817566197852193 3.13768461673246 1.0353571830971275 1.549676140593033 0.47761057816227903 0.14473024636660584 0.25626660605498586 3.96134452197427 0.03442763751593097 0.31432241566591823 1.5220671123105914e-05 4.817566197852193 0.5143189574959055 RALS(ph)SAGPIPIRPPIVPVK ddPTM_PC-9_AZD4547_30min_R2 1 RALSSAGPIPIRPPIVPVK 19 2 A0A087WXN9;Q765P7 A0A087WXN9 MTSS1L MTSS1-like protein 1 RALS(0.837)S(0.163)AGPIPIRPPIVPVK 51.495 0.016568 4688300.0 20208.0 15327.0 23505.0 32864.0 27510.0 24425.0 21354.0 32866.0 19938.0 25409.0 True False 26633.723647488325 20281.15301417909 23193.308342105815 25287.712543738537 23690.71135716548 22897.700888823274 23254.464631820585 27787.314885546748 20991.881975766275 24519.438643897676 1.0862289318404459 0.8271458946808556 0.9459151442636349 1.0313332581140502 0.9662012128920232 0.9338590993608242 0.9484093404237901 1.1332769599300092 0.8561322418770249 1.0 14.581638329420901 RALS(ph)SAGPIPIRPPIVPVK ddPTM_PC-9_Lapatinib_30min_R1 2 RALSSAGPIPIRPPIVPVK 19 2 A0A087WXN9;Q765P7 A0A087WXN9 MTSS1L MTSS1-like protein 1 RALS(0.894)S(0.106)AGPIPIRPPIVPVK;RALS(0.811)S(0.189)AGPIPIRPPIVPVK 59.861999999999995 0.0067169 10629600.0 70405.0 46635.0 62892.0 48432.0 50879.0 46626.0 46557.0 40846.0 68073.0 38956.0 True False 69401.01178930435 46527.01952274587 57721.26253014062 51993.85084441579 47886.39725196271 44631.91467051464 48967.49365484942 42743.85427565409 60405.90189953106 45689.49269439286 1.5189709426960092 1.0183308410525598 1.2633377856967174 1.1379826690611652 1.0480833650805552 0.9768529269748708 1.0717451818163621 0.9355291940218836 1.3220961393371795 1.0 15.4795748034627 -4.755954202186802 24.99995612264483 1.0861064096384139 1.518971626574606 0.5499667019957458 0.11750019810937991 133.0944074139767 606544.4178711982 0.02862702721936203 0.24189506694509888 1.7540654641894365e-05 4.755954202186802 0.4328652169361922 RALS(ph)SDSILSPAPDAR ddPTM_PC-9_AZD4547_30min_R2 4 RALSSDSILSPAPDAR 16 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 RALS(0.447)S(0.14)DS(0.414)ILSPAPDAR;RALS(0.967)S(0.023)DS(0.009)ILS(0.001)PAPDAR;RALS(0.442)S(0.139)DS(0.418)ILSPAPDAR;RALS(0.819)S(0.109)DS(0.069)ILS(0.003)PAPDAR 164.74 2.6616e-05 188124400.0 69056.7 52798.2 102708.0 149443.0 117692.0 95137.9 93005.2 121770.0 92923.0 107270.0 True False 91015.29413140863 69864.18562492527 101346.02481178496 114991.22522133384 101352.4973117962 89188.91207331758 101282.48262505374 102953.24449622768 97834.7200739357 103514.50995044684 0.8792515578248724 0.6749216671012573 0.9790513896100175 1.1108705946285307 0.9791139170761123 0.8616078278882155 0.9784375414957615 0.9945779055082438 0.9451304954326685 1.0 16.659473483382016 -5.281621055409108 24.26749409274024 0.981106335549215 0.7770866315291837 0.5529388947115434 0.07337713754658354 353.025444650886 424495.8363213607 0.01954695112374076 0.04078076620799073 5.228522058456833e-06 5.281621055409108 -0.20401970402003133 RALS(ph)SDSILSPAPDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RALSSDSILSPAPDAR 16 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 RALS(0.821)S(0.016)DS(0.146)ILS(0.016)PAPDAR;RALS(0.819)S(0.015)DS(0.161)ILS(0.005)PAPDAR 116.61 0.0002299 92675000.0 25997.2 24120.9 29191.5 36574.0 50024.0 42918.0 38234.0 50113.0 37190.0 24802.5 True False 30398.012491894846 26515.463542525387 29887.53606938024 34524.877354507844 40222.156300288676 40667.304527178996 34612.19872981118 48797.586849112486 37733.83339343238 29298.99691351803 1.037510348276454 0.9049956085797474 1.020087348300674 1.1783638005224228 1.3728168380307553 1.3880101304224457 1.1813441542717709 1.6655036687142746 1.2878882340174134 1.0 14.838563652638431 -5.925236818356178 2.3234439830829383 1.3460388655802742 0.9698420236843261 0.4426039176674348 0.16290601387022352 0.24067713313595615 2.6340511934670134 0.048220718252074767 0.07868439443708271 1.18785432047426e-06 5.925236818356178 -0.37619684189594804 RALS(ph)SDSILSPAPDAR ddPTM_PC-9_Lapatinib_30min_R1 4 RALSSDSILSPAPDAR 16 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 RALS(0.917)S(0.08)DS(0.003)ILSPAPDAR;RALS(0.668)S(0.03)DS(0.302)ILSPAPDAR;RALS(0.625)S(0.185)DS(0.19)ILSPAPDAR;RALS(0.872)S(0.083)DS(0.044)ILSPAPDAR 213.36 1.0131e-21 179147500.0 136576.0 79653.5 110921.7 91004.8 97286.4 85231.7 64940.0 63215.1 100894.9 75155.7 True False 134628.40119502906 79469.06721464633 101802.14599614423 97697.59657511313 91564.20522442156 81586.53887579679 68302.27544613964 66152.30432406848 89531.05389160155 88146.2626063247 1.52732965884556 0.9015591230403935 1.1549229994107508 1.108357787231958 1.0387758087187648 0.9255813742231512 0.7748743216849535 0.7504833712521113 1.0157101531514903 1.0 16.427611780250572 -6.498838645798292 1.3946032559250174 0.8626447473700203 1.169926688321876 0.3976619706571489 0.1627663152542866 0.42656967278400476 1.7043449827658093 0.06598590540720718 0.07494339946177621 3.170745276867505e-07 6.498838645798292 0.3072819409518557 RALS(ph)TTSSSTTNGNR ddPTM_PC-9_Lapatinib_30min_R1 1 RALSTTSSSTTNGNR 15 1 A0A0A0MT72;Q9BSQ5-4;Q9BSQ5;Q9BSQ5-2;C9JUH3;Q9BSQ5-3 A0A0A0MT72 CCM2 Cerebral cavernous malformations 2 protein 1 RALS(0.509)T(0.159)T(0.05)S(0.016)S(0.016)S(0.084)T(0.084)T(0.084)NGNR 77.726 0.02515 0.0 2712.6 1225.7 1768.2 951.51 852.34 951.35 1240.7 745.43 2069.2 1046.6 True False 2673.917826570084 1222.8619669567836 1622.8254214493827 1021.4872195443102 802.2070369649146 910.6629782051668 1304.9373752082754 780.0653991260057 1836.1449063580221 1227.50341549316 2.1783384003830366 0.9962187897175735 1.322053691229363 0.8321664988067825 0.6535273359240479 0.7418822356916215 1.0630824800467098 0.6354893919481338 1.495836902107792 1.0 10.261511323465346 -2.7632175336394647 1.2500190295278897 0.9173160601002049 199.99999998254194 0.6387383511438841 0.26915857026197987 142.9284282726219 1.8564531563703643 0.07627785283097518 79970.8456875514 0.0017249736540015906 2.7632175336394647 199.08268392244173 RALSSDS(ph)ILSPAPDAR ddPTM_PC-9_AZD4547_30min_R2 1 RALSSDSILSPAPDAR 16 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 RALS(0.054)S(0.005)DS(0.911)ILS(0.031)PAPDAR 201.75 2.0138e-12 134400000.0 24338.0 16971.0 29105.0 45295.0 50691.0 30882.0 35702.0 41493.0 28735.0 37102.0 True False 32076.977738151745 22456.54386400688 28719.04868313082 34852.93755077403 43653.429640351715 28950.943658081505 38879.40883606158 35081.210264285015 30253.873436334812 35803.07027296989 0.8959281283306249 0.6272239696985097 0.8021392708550119 0.9734622557520388 1.219264976649463 0.8086162286461362 1.0859238757915748 0.9798380417326987 0.8450077941828209 1.0 15.12779568987862 -5.724049752716483 4.301535767242238 0.9940047331941951 0.753025509748468 0.3840043106182407 0.12360084867976666 0.19363707784584294 7.806069378824459 0.03355124255800105 0.05786241948274569 1.8877750734539021e-06 5.724049752716483 -0.2409792234457271 RALSSDS(ph)ILSPAPDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RALSSDSILSPAPDAR 16 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 RALS(0.052)S(0.016)DS(0.929)ILS(0.002)PAPDAR;RALS(0.019)S(0.002)DS(0.974)ILS(0.006)PAPDAR 168.55 4.2057e-05 93176000.0 17600.1 14788.6 21967.5 36663.0 37350.0 35650.0 31594.0 47264.0 37708.0 23983.2 True False 20579.449312179728 16256.71447354746 22491.28851220769 34608.89097304976 30031.535619218394 33780.45124176175 28601.187599248165 46023.37008034747 38259.408163472646 28331.16430909326 0.7263891129802414 0.573810320542656 0.7938709566196267 1.2215837865139056 1.0600176996460176 1.1923424986427216 1.0095309634016079 1.6244785981342695 1.3504354337881126 1.0 14.790102272068099 -5.679831746626383 3.267699726354049 1.2229601370759313 0.6524289402590043 0.639259966949815 0.17726173553386884 0.15341613869085388 3.251135769569564 0.05277704997094331 0.09678566397292543 2.090105717990505e-06 5.679831746626383 -0.570531196816927 RALSSDS(ph)ILSPAPDAR ddPTM_PC-9_Lapatinib_30min_R1 2 RALSSDSILSPAPDAR 16 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 RALS(0.235)S(0.024)DS(0.676)ILS(0.065)PAPDAR;RALS(0.227)S(0.024)DS(0.569)ILS(0.18)PAPDAR 123.63 5.6213999999999994e-05 130990000.0 92354.0 60636.0 77931.0 65071.0 68414.0 66075.0 49090.0 52167.0 71883.0 48704.0 True False 91037.01502435059 60495.601067464704 71523.81400235924 69856.53841049258 64390.02302709906 63249.12627834807 51631.640000785235 54590.869264996545 63786.77957845241 57122.421505999315 1.5937177140641592 1.0590517606315257 1.2521145308037653 1.2229267697125874 1.1272285265486592 1.1072556906871551 0.9038769477824499 0.9556819866129643 1.1166679894995903 1.0 15.801769518241539 -1.5228787452803376 0.3955855220225257 1.0052890993476913 8.317093769929857 0.6251532500136705 0.11332164086036944 50.92347510683818 0.6801402759184486 0.08460952501367457 289.16330786649945 0.029999999999999995 1.5228787452803376 7.311804670582165 RALSSDSILS(ph)PAPDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RALSSDSILSPAPDAR 16 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 RALS(0.312)S(0.005)DS(0.325)ILS(0.358)PAPDAR 109.55 0.00098454 18285000.0 19026.0 12303.0 21300.0 29809.0 33639.0 30017.0 28697.0 37152.0 29422.0 28470.0 True False 22246.726019371006 13524.360532305594 21807.87278069983 28138.898372081934 27047.679429582025 28442.85567809151 25978.612411711878 36176.79936579783 29852.24108904457 33631.385631604004 0.6614870485284248 0.402135097270465 0.6484381291803388 0.8366856685690439 0.8042392224293264 0.8457235746886164 0.7724514445012732 1.0756856634477128 0.8876304240343846 1.0 15.037520599468426 -5.846246047055574 0.5087646119338495 0.9744833094857667 0.4255738725372332 0.6799171986468984 0.10245059489149427 0.977923394472299 0.4059027774168119 0.0775729817879036 0.28740032300593926 1.4248001525183334e-06 5.846246047055574 -0.5489094369485334 RALVEFESNPEET(ph)REPGSPPSVQR ddPTM_PC-9_AZD4547_30min_R2 1 RALVEFESNPEETREPGSPPSVQR 24 2 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 RALVEFES(0.001)NPEET(0.947)REPGS(0.039)PPS(0.012)VQR 53.033 0.0067774 25237000.0 20839.0 5766.6 18976.0 42602.0 25971.0 22587.0 13689.0 15528.0 16166.0 19646.0 True False 27465.368521872962 7630.540677990806 18724.36584130186 32780.76709433876 22365.37494209176 21174.631319379783 14907.29448089314 13128.504397942246 17020.50175645689 18958.199519777016 1.4487329608078736 0.4024928986547851 0.9876658288024017 1.7291076117298043 1.1797204116751916 1.1169115135269363 0.7863243798727823 0.6924974275245238 0.8977910449091573 1.0 14.210534336020286 -7.254828525760094 19.762869498013757 0.8185279612003369 1.1314948606538673 0.16577734535269273 0.32689227005841126 57.954654391549504 173256.58971127393 0.13485083798708186 0.10126123092981412 5.561237905245874e-08 7.254828525760094 0.3129668994535304 RALVEFESNPEET(ph)REPGSPPSVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RALVEFESNPEETREPGSPPSVQR 24 2 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 RALVEFESNPEET(0.966)REPGS(0.027)PPS(0.006)VQR;RALVEFESNPEET(0.901)REPGS(0.073)PPS(0.026)VQR 53.718 0.0051722 17563800.0 11856.3 15611.0 7285.9 24735.1 26223.1 28185.3 19490.1 30089.6 31387.4 18956.6 True False 13863.337417400842 17160.756910495198 7459.623487929619 23349.272539276193 21084.871799098437 26707.213250615092 17643.856631895524 29299.7798825665 31846.38134587309 22393.281519636977 0.6190846752515432 0.766335067749972 0.3331188187576784 1.0426909749158868 0.9415713271236653 1.1926440181263818 0.787908490161363 1.3084183243475558 1.422139998460992 1.0 14.450778336288948 -5.865046721742808 7.032552009456832 1.101038845473443 0.5941708900550404 0.600623480659304 0.19689776644436227 0.15713263549058082 9.388163443452019 0.05700074726093006 0.08516673035443671 1.3644363415554088e-06 5.865046721742808 -0.5068679554184026 RALVEFESNPEET(ph)REPGSPPSVQR ddPTM_PC-9_Lapatinib_30min_R1 1 RALVEFESNPEETREPGSPPSVQR 24 2 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 RALVEFES(0.001)NPEET(0.775)REPGS(0.056)PPS(0.168)VQR 46.568999999999996 0.021938 20914000.0 54460.0 19458.0 24162.0 12944.0 17017.0 16994.0 8137.1 13310.0 18878.0 14781.0 True False 53683.39041325914 19412.94619649595 22175.49362801719 13895.944939918189 16016.093516709243 16267.206234948859 8558.399222863916 13928.431190543903 16751.760845847068 17335.876155555507 3.0966643930514928 1.1198133871229126 1.279167746068073 0.8015715395766169 0.9238698623015185 0.9383550095179828 0.4936813776280506 0.8034454714352788 0.9663059827800367 1.0 14.081473131771332 -2.9305753992780956 1.2199885762285005 0.8475485424936655 199.99999998949284 0.9192500027286283 0.19337727459442375 33.28551385793919 0.7335717353262062 0.056838755025443034 17908.592886423885 0.0011733419570921363 2.9305753992780956 199.15245144699918 up RAPAPLGAS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 2 RAPAPLGASPAR 12 1 Q2QGD7-2;Q2QGD7 Q2QGD7-2 ZXDC Zinc finger protein ZXDC 1 RAPAPLGAS(1)PAR;RAPAPLGAS(1)PAR 90.853 0.0030816999999999997 10196100.0 25448.6 29305.2 42057.0 62438.0 53380.0 44347.0 38366.0 50310.0 36054.0 46497.0 True False 33540.725436236695 38777.53280557976 41499.29670044435 48043.88375748381 45969.108405870335 41573.97507949421 41780.49967520975 42535.74550878891 37959.74083430017 44869.154182585335 0.7475230154718308 0.8642358767848166 0.9248958991197365 1.0707552801637312 1.0245147082293768 0.9265602580854966 0.9311630770928515 0.9479952605234964 0.8460097259652188 1.0 15.453436367929855 -4.949494967412406 2.030970484918314 0.9619672926754708 0.7264274082180427 0.5677025384117699 0.05831285892096815 0.3968520806225095 2.372564362512693 0.01715181700214613 0.15460847833823835 1.1233239866336465e-05 4.949494967412406 -0.23553988445742802 RAPAPLGAS(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RAPAPLGASPAR 12 1 Q2QGD7-2;Q2QGD7 Q2QGD7-2 ZXDC Zinc finger protein ZXDC 1 RAPAPLGAS(1)PAR;RAPAPLGAS(1)PAR 82.57799999999999 0.0054828 7244200.0 41086.0 40800.0 45901.0 47067.0 53672.0 48527.0 44167.0 39315.0 38907.0 33811.0 True False 48041.04831451048 44850.35436219361 46995.4539205119 44429.988583272825 43155.3568876758 45982.158693098805 39983.18201861097 38283.022907685794 39475.94127018753 39940.666652271284 1.2028103770215501 1.1229245308463855 1.176631685436313 1.1123997746478838 1.0804866444366599 1.151261672556083 1.001064463112492 0.9584973440975045 0.9883646062763621 1.0 15.285570792649292 -7.311684983504397 4.732982175819031 0.9806687482084963 1.1380753716892966 0.8360375660040547 0.03343457327608273 0.08469632535518394 4.239949477149094 0.014637986056170066 0.009862458491443939 4.878822482927198e-08 7.311684983504397 0.15740662348080037 RAPAPLGAS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 2 RAPAPLGASPAR 12 1 Q2QGD7-2;Q2QGD7 Q2QGD7-2 ZXDC Zinc finger protein ZXDC 1 RAPAPLGAS(1)PAR;RAPAPLGAS(1)PAR 85.163 0.0044995 9339300.0 32857.0 29097.0 35055.0 27491.0 33352.0 37717.0 29177.0 27616.0 34227.0 24271.0 True False 32388.453154764153 29029.627684214345 32172.913216213194 29512.779847287627 31390.300932554874 36103.931832621296 30687.642295842557 28899.14017716457 30371.9948337116 28466.210010925384 1.1377859273269397 1.019792507435051 1.130214145257313 1.0367653381310884 1.1027214694371754 1.2683083493996756 1.0780375147961243 1.0152085636294057 1.0669490185751729 1.0 14.796962805105288 -7.527230662974886 21.823647032736027 1.0339716679467157 1.1134417283797347 0.2695258376013818 0.06497355433209576 40.81089695324466 204626.78895526723 0.03163816078063446 0.01841243460289123 2.970088136188685e-08 7.527230662974886 0.07947006043301896 RAPFDLFENK ddPTM_PC-9_AZD4547_30min_R2 2 RAPFDLFENK 10 1 P08238;Q58FF7 P08238 HSP90AB1;HSP90AB3P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 ; 131.42 0.00011418 9543700.0 78254.0 78267.0 84960.0 104858.0 89765.0 89326.0 78843.0 84811.0 77544.0 85735.0 False True 103137.14421568454 103565.27715539609 83833.37488812218 80684.60813995061 77302.67920668682 83740.43109907987 85859.87426087073 71705.40871289781 81642.8175307865 82733.44374570316 1.246619741016656 1.2517945883374986 1.0132948792244145 0.9752357026011146 0.9343582922075767 1.0121714666740076 1.037789198341329 0.8667040251980554 0.9868175895316421 1.0 16.336183014541767 -5.305108435259889 3.6787883233453114 0.9717706091122725 1.2554009822801253 0.8567907360191036 0.04450212390711594 0.07469279893099945 2.109427994756848 0.012140620207642266 0.030232218252861796 4.953265015431884e-06 5.305108435259889 0.2836303731678528 RAPFDLFENK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RAPFDLFENK 10 1 P08238;Q58FF7 P08238 HSP90AB1;HSP90AB3P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 106.4 0.0014692 3397400.0 14240.0 15843.0 17715.0 20164.0 17824.0 14997.0 19056.0 19858.0 15496.0 10498.0 False True 16650.550747179805 17415.788337260616 18137.392784511634 19034.276452570037 14331.515150654588 14210.53091929035 17250.877726507348 19336.748541290213 15722.599684448182 12401.204297877717 1.3426559507635318 1.4043626666356162 1.4625509223822384 1.534873226451682 1.1556551127141108 1.1458992673576285 1.3910647153405562 1.5592637680035166 1.2678284549460146 1.0 13.598192609049574 -8.541134402508698 22.416757419291326 0.9999999902034629 1.3722023496649816 0.43043808082651847 0.1303784907168285 960.757555631302 1179748.072942832 0.1369481622470151 0.035359863444181294 2.8765080747785015e-09 8.541134402508698 0.3722023594615187 RAPFDLFENK ddPTM_PC-9_Lapatinib_30min_R1 2 RAPFDLFENK 10 1 P08238;Q58FF7 P08238 HSP90AB1;HSP90AB3P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 ; 140.78 7.649600000000001e-05 10766900.0 92816.0 96496.0 86082.0 92643.0 106225.0 81248.0 100332.0 92270.0 90743.0 93140.0 False True 91492.42681963035 96272.5694406965 79004.67024612933 99456.27526798812 99977.05434638538 77773.21243833847 105526.70003175379 96557.20104819581 80522.56777384781 109239.1248987513 0.8375426561173065 0.8813011778511326 0.7232268687556324 0.9104455510804353 0.9152128821889548 0.7119538215856532 0.9660156114355696 0.8839067608577992 0.7371220508080824 1.0 16.737130136445685 -10.670921194073346 4.2182593228322265 1.0000375666228276 0.8438895533963536 0.24297493249548185 0.08416567126107388 22372284.379868377 28297562.546622325 6435.684311155957 0.019699317299331772 2.1334320049473787e-11 10.670921194073346 -0.15614801322647398 RAPFDLFENR ddPTM_PC-9_AZD4547_30min_R2 2 RAPFDLFENR 10 1 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ; 141.08 7.8638e-05 90910000.0 124780.0 135371.0 132768.0 162095.0 156952.0 134737.0 129397.0 150913.0 115862.0 116403.0 False True 164457.44441476616 179127.02842581313 131007.40957092975 124726.50209278538 135161.9239887252 126311.87409037414 140913.0823247957 127592.86348574582 121986.22878303909 112327.76640031558 1.4640854143637998 1.5946816550009302 1.166295865832882 1.1103799718431413 1.2032815066137152 1.1244937751207638 1.2544812991527605 1.1358978067010452 1.0859846384579794 1.0 16.7773550673275 -5.269925133326416 23.375601528788057 1.145392065121219 1.5293835405400251 0.8303743701585364 0.07115977261528593 80.38922688491087 221448.76279862615 0.01759645011645088 0.03769934872320902 5.3712438158962e-06 5.269925133326416 0.38399147541880607 RAPFDLFENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RAPFDLFENR 10 1 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ; 160.18 9.4416e-05 80556000.0 144980.0 135524.0 131987.0 144717.0 130746.0 118266.0 132255.0 150659.0 124708.0 103851.0 False True 169522.25051447528 148977.92707308673 135134.07064348517 136608.97566884418 105127.25986801436 112063.92276460576 119726.84895671869 146704.36088640543 126531.61857564299 122678.36421593658 1.3818430951368474 1.2143781670487395 1.1015314029263077 1.1135539387237603 0.8569339878299238 0.913477478126074 0.9759410285743403 1.1958454273826038 1.0314094044563877 1.0 16.904521309495678 -4.9794076693880385 1.1538987735059625 1.0065573450229421 1.4764546538052634 0.6479663490406363 0.08825010040489167 0.8218875996461363 1.16695804124824 0.031207227010451487 0.4306869859656268 1.0485576922980897e-05 4.9794076693880385 0.4698973087823213 RAPFDLFENR ddPTM_PC-9_Lapatinib_30min_R1 2 RAPFDLFENR 10 1 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ; 147.91 9.3588e-05 59973000.0 170947.0 199098.0 184659.0 194677.0 223420.0 203735.0 198320.0 221619.0 188328.0 201542.0 False True 168509.26443215949 198637.00081354438 169477.04982435383 208994.19600343384 210278.87486062016 195021.7289794815 208588.03921278744 231916.22779993617 167116.5174582417 236378.26616216564 0.7128796871559879 0.8403352983276003 0.7169739104020896 0.8841514890377224 0.8895863324268561 0.825040864144795 0.8824332397365462 0.9811233137687526 0.7069876608012371 1.0 17.850737867221703 -1.5228787452803376 0.1002963029619996 1.0321815587611842 0.22701528552537217 0.319435421688804 0.08281727325096272 156.2270985492118 1.1142641535075193 1.015339083044589 17.309075879079863 0.029999999999999995 1.5228787452803376 -0.805166273235812 RAPQAFEHSDVDGVVTSTDPVPEPEPS(ph)PLESK ddPTM_PC-9_AZD4547_30min_R2 1 RAPQAFEHSDVDGVVTSTDPVPEPEPSPLESK 32 1 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 RAPQAFEHSDVDGVVTSTDPVPEPEPS(0.892)PLES(0.108)K 104.83 6.284600000000001e-16 10939000.0 13367.0 12634.0 16743.0 22963.0 19598.0 19630.0 15220.0 15651.0 16514.0 16969.0 True False 17617.427949127887 16717.693428664363 16520.97688031815 17669.235124813407 16877.15598610428 18402.532996831145 16574.550514953135 13232.497574201057 17386.896326000802 16374.920474961624 1.0758786875372093 1.0209328011227208 1.0089195184538367 1.0790424998906638 1.0306710198630038 1.1238242668091047 1.012191206686882 0.8080953794208927 1.0618003521047055 1.0 13.999200279747196 -7.531675859463062 24.99999185640217 0.9429973686341082 1.0538911629947902 0.3010449755863739 0.06724325470058458 210.03162809861428 596867.5899176807 0.029468981209600797 0.017044809751255132 2.939843018007886e-08 7.531675859463062 0.11089379436068203 RAPQASGPS(ph)TPGYR ddPTM_PC-9_Lapatinib_30min_R1 2 RAPQASGPSTPGYR 14 1 Q2QGD7-2;Q2QGD7 Q2QGD7-2 ZXDC Zinc finger protein ZXDC 1 RAPQASGPS(0.5)T(0.5)PGYR;RAPQASGPS(0.5)T(0.5)PGYR 92.427 0.0019027999999999998 13031700.0 22845.0 23335.0 22663.0 15801.6 21415.2 17924.8 15429.400000000001 19582.8 23697.0 9293.7 True False 22519.226110740077 23280.969241198123 20799.735621709875 16963.70237659235 20155.60003990314 17158.19808874964 16228.258835365983 20492.688378526145 21027.994319527366 10900.103661923167 2.0659643989814023 2.1358484252332817 1.9082144782135089 1.5562881696117143 1.8491200327123287 1.5741316432326773 1.4888169267651477 1.8800452742584748 1.929155443996693 1.0 13.41205423490315 -11.651574702599497 0.12417948999208214 1.363336548159686e-26 2.2332929406368893 0.5973770761826871 0.20369011700452555 49.36719025572665 0.8375989229963039 18.30235803384232 2.4299121783098507 2.230618487820557e-12 11.651574702599497 2.2332929406368893 RAPQASGPST(ph)PGYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RAPQASGPSTPGYR 14 1 Q2QGD7-2;Q2QGD7 Q2QGD7-2 ZXDC Zinc finger protein ZXDC 1 RAPQASGPS(0.252)T(0.746)PGY(0.002)R 64.327 0.035226 2467200.0 7526.4 6004.0 7934.6 6969.0 8996.9 7141.5 8179.4 8999.5 9492.6 5827.0 True False 8800.47086682402 6600.0374409463375 8123.790956138072 6578.549523802844 7234.022029787048 6766.98716810776 7404.588018272155 8763.272660758443 9631.411316765158 6883.388973493382 1.278508435410661 0.9588354611895133 1.1802022212345171 0.9557137551191113 1.050939015308286 0.9830894627873185 1.0757183775006485 1.273104381359841 1.3992252005304198 1.0 12.74890332218612 -7.7378095484263145 7.754409715184495 1.2522942002802167 1.0603124620661306 0.21384441092600692 0.13234517439248436 0.20824308661970345 52.15172673232124 0.06051420185374538 0.033685103248698695 1.8289020704815833e-08 7.7378095484263145 -0.19198173821408604 RAPS(ph)PDGFSPYSPEETNR ddPTM_PC-9_AZD4547_30min_R2 2 RAPSPDGFSPYSPEETNR 18 1 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 RAPS(1)PDGFSPYSPEETNR;RAPS(1)PDGFSPYSPEETNR 114.76 6.3217e-05 18001200.0 13279.6 12405.6 23552.0 28522.0 22088.8 26852.0 11786.5 27367.0 15814.6 20859.4 True False 17502.236567160813 16415.467595269794 23239.685091396565 21946.693560507276 19022.15140044191 25172.940195155883 12835.475666523991 23138.05898109771 16650.527469854213 20129.118755107214 0.8694984008040639 0.8155085075994605 1.154530676386423 1.0902957962299717 0.9450066658092302 1.2505733858204269 0.6376571087230205 1.1494819650376924 0.827186111445122 1.0 14.29699639257044 -10.491749009764785 14.734411882313777 0.9999573376769434 0.9783021588648395 0.0008704476958744101 0.18037653521997712 0.0 0.0 0.1666660604540211 0.040422457144559276 3.222930869911033e-11 10.491749009764785 -0.02165517881210388 RAPS(ph)PDGFSPYSPEETNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RAPSPDGFSPYSPEETNR 18 1 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 RAPS(0.998)PDGFS(0.001)PYSPEETNR;RAPS(0.874)PDGFS(0.033)PY(0.04)S(0.049)PEET(0.004)NR;RAPS(1)PDGFSPYSPEETNR 129.2 1.9289e-05 23279700.0 29833.300000000003 30340.600000000002 41738.9 37007.4 40945.0 39088.5 30863.1 28339.9 30182.5 23118.100000000002 True False 34883.488455466235 33352.61425396007 42734.11367165973 34933.99535760963 32922.12117614184 37038.63024862847 27939.52373850593 27596.007653606106 30623.861962819916 27309.228527221105 1.2773516623032874 1.2212946338163702 1.5648231743003476 1.279201106790269 1.205530985370969 1.3562679081801727 1.0230799347061952 1.010501180071753 1.121374114698805 1.0 14.737100938776303 -7.26423319057681 24.969435368968103 1.0396138910228496 1.3174662910443702 0.6578910021901327 0.09844685169810515 159.36739777034146 1424319.689243924 0.041202357159307444 0.029158507255683686 5.442103654415977e-08 7.26423319057681 0.27785240002152056 RAPS(ph)PDGFSPYSPEETNR ddPTM_PC-9_Lapatinib_30min_R1 4 RAPSPDGFSPYSPEETNR 18 1 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 RAPS(1)PDGFSPYSPEETNR;RAPS(0.989)PDGFS(0.007)PY(0.002)S(0.002)PEETNR;RAPS(1)PDGFSPYSPEETNR;RAPS(0.524)PDGFS(0.184)PY(0.25)S(0.041)PEETNR 161.96 1.3126e-06 26683200.0 55891.0 53386.3 61815.0 45238.7 54908.0 56288.2 51011.1 50244.6 54790.2 43892.8 True False 55093.98409084587 53262.68730239449 56732.80931280039 48565.70490987928 51678.419393281474 53880.88490020295 53652.205158770754 52579.1475429303 48619.150709615955 51479.611996520325 1.0702097773108674 1.0346365335075698 1.1020442290170165 0.9433968716229251 1.0038618666507158 1.0466451243619501 1.042202982462208 1.021358660327205 0.9444350651458344 1.0 15.651713559510444 -1.5228787486176583 0.29323011261985826 0.9973014294052436 1.6075108899533501 0.2292290383264488 0.0420146052852443 90.862340802158 1.2914724689647405 0.04571947746271337 28.8570275825431 0.029999999769466053 1.5228787486176583 0.6102094605481065 RAPS(ph)PGAYK ddPTM_PC-9_AZD4547_30min_R2 3 RAPSPGAYK 9 1 P54259 P54259 ATN1 Atrophin-1 1 RAPS(1)PGAYK;RAPS(1)PGAYK;RAPS(1)PGAYK 78.705 0.009724700000000001 94071000.0 109463.0 98123.0 146204.0 183814.0 167374.0 155529.0 130720.0 156281.0 137923.0 140505.0 True False 144269.95702815804 129839.34085015296 144265.23943200344 141438.52219799042 144137.00918554032 145803.7470435124 142353.82676180507 132131.36243011433 145213.32820461472 135585.96271639384 1.064047886210231 0.9576163951554401 1.0640130920762358 1.0431649365785631 1.0630673433874034 1.0753601930643157 1.0499156690694273 0.9745209591238768 1.0710056210491237 1.0 17.048848297691784 -5.350395157921151 24.59248649522187 1.0438989925634488 1.010774977270898 0.09701746839530634 0.03864927615381746 116.37669636457754 32168.248834349277 0.009822300342518133 0.020446750738058343 4.462773464138984e-06 5.350395157921151 -0.03312401529255071 RAPS(ph)PGAYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RAPSPGAYK 9 1 P54259 P54259 ATN1 Atrophin-1 1 RAPS(1)PGAYK 62.799 0.027578 26048000.0 35314.0 39059.0 39994.0 46057.0 58529.0 45538.0 47907.0 46230.0 42597.0 38683.0 True False 41291.96271670698 42936.519388061766 40947.608638089645 43476.57560880866 47060.66260394203 43149.9071149326 43368.902143355765 45016.51148473391 43219.900539393355 45695.92168554051 0.9036246823263646 0.939613816820071 0.8960889096377858 0.9514322942864698 1.029865705035847 0.9442835492381907 0.9490759906715903 0.9851319291580984 0.945815270710895 1.0 15.47977779151555 -5.971197657458453 7.716588619432929 0.9737188958411189 0.9168033431397394 0.5141158413544605 0.027112563162527477 0.17207867116724523 36.67609839263668 0.007576776500197645 0.011166929705606218 1.0685684383370472e-06 5.971197657458453 -0.05691555270137949 RAPS(ph)PGAYK ddPTM_PC-9_Lapatinib_30min_R1 3 RAPSPGAYK 9 1 P54259 P54259 ATN1 Atrophin-1 1 RAPS(1)PGAYK;RAPS(1)PGAYK;RAPS(0.999)PGAY(0.001)K 82.48899999999999 0.010671 101703000.0 167950.0 150880.0 154355.0 153762.0 147299.0 153366.0 126409.0 129632.0 140333.0 125404.0 True False 165555.00220174206 150530.64663003982 141664.52772753092 165070.1704149956 138635.16242097635 146806.89369360765 132953.8394960126 135655.17596488248 124527.21976799748 147079.9143096733 1.1256125826478922 1.0234616149768831 0.963180651773155 1.1223161992564412 0.9425839216161309 0.9981437260325647 0.9039564655720523 0.9223229194930295 0.8466636682001891 1.0 17.166240715561386 -6.7426242720897775 1.2006822129977825 0.9110760303531398 1.050257527730541 0.464974272078835 0.0622437291842411 0.40693899855423254 1.2394881524411725 0.03038381111876198 0.027888696946109702 1.8087382710557862e-07 6.7426242720897775 0.13918149737740126 RAPS(ph)PLPK ddPTM_PC-9_AZD4547_30min_R2 2 RAPSPLPK 8 1 Q9BSL1 Q9BSL1 UBAC1 Ubiquitin-associated domain-containing protein 1 1 RAPS(1)PLPK;RAPS(1)PLPK 61.213 0.030605 61330000.0 139454.0 141493.0 179236.0 232568.0 208149.0 192138.0 183356.0 206940.0 170881.0 197174.0 True False 183797.4711766054 187227.84520357815 176859.21352927823 178953.0407397816 179251.10426327327 180123.5804862533 199674.32879236172 174962.17800812493 179913.42079952412 190270.9982750944 0.9659773315051958 0.9840062169268884 0.9295121964597811 0.9405166439556424 0.9420831650029579 0.9466686048802355 1.0494207241382734 0.91954201951032 0.9455640766618817 1.0 17.537696152531772 RAPS(ph)PLPK ddPTM_PC-9_Lapatinib_30min_R1 1 RAPSPLPK 8 1 Q9BSL1 Q9BSL1 UBAC1 Ubiquitin-associated domain-containing protein 1 1 RAPS(1)PLPK 62.166000000000004 0.028887 52500000.0 185540.0 164080.0 176380.0 154920.0 155440.0 161160.0 146090.0 124670.0 159720.0 124920.0 True False 182894.16557613126 163700.0828410455 161878.71724648902 166313.3335979701 146297.32480679825 154267.5624823088 153653.8253761403 130462.62333021128 141730.65167383675 146512.2555545632 1.2483199093745365 1.1173132392332963 1.1048817495421273 1.135149636243452 0.9985330186409908 1.0529328205233823 1.0487438391726724 0.8904553604502061 0.9673637958638505 1.0 17.16066182364593 -5.057624716948066 0.37675785399175765 0.9515014655575638 1.3693213918026457 0.7377174529869527 0.04889776502657588 2.5963399993088663 0.3427922816352194 0.045768325251983495 0.4839935822631376 8.757401939948372e-06 5.057624716948066 0.4178199262450819 RAPS(ph)PVVSPTEMNK ddPTM_PC-9_AZD4547_30min_R2 3 RAPSPVVSPTEMNK 14 1 Q9UPX8;Q9UPX8-3;H7C1X5;E7EUA2;A6NHU9;A0A0A0MSQ6;A0A590UJ45;Q9UPX8-4 Q9UPX8 SHANK2 SH3 and multiple ankyrin repeat domains protein 2 1 RAPS(0.999)PVVS(0.001)PTEMNK;RAPS(1)PVVSPTEMNK;RAPS(1)PVVSPTEMNK 103.3 0.005191899999999999 27634000.0 88270.0 116610.0 114114.0 119261.0 113712.0 136284.0 114141.0 151923.0 126280.0 132494.0 True False 116338.0238699423 154301.9020671642 112600.77379923701 91767.21901408228 97925.05161199548 127762.13993581939 124299.3278795841 128446.7911932366 132954.9029942703 127855.42538803507 0.9099185546241937 1.2068467301944 0.8806882731608695 0.7177420804441671 0.7659045465986105 0.9992703833104261 0.9721865732513236 1.0046252695449314 1.0398847181553583 1.0 16.964153855308453 -6.937065561883244 24.99963569575978 1.00187339092449 0.9006873673482728 0.16132915806990566 0.12173387870468846 150.4960775036824 59780.7068060445 0.048471612807755436 0.04274794017891411 1.1559377265625719e-07 6.937065561883244 -0.10118602357621709 RAPS(ph)PVVSPTEMNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RAPSPVVSPTEMNK 14 1 Q9UPX8;Q9UPX8-3;H7C1X5;E7EUA2;A6NHU9;A0A0A0MSQ6;A0A590UJ45;Q9UPX8-4 Q9UPX8 SHANK2 SH3 and multiple ankyrin repeat domains protein 2 1 RAPS(1)PVVSPTEMNK;RAPS(0.999)PVVSPTEMNK;RAPS(1)PVVSPTEMNK 99.81299999999999 0.00078637 41229000.0 119377.0 160142.0 150670.0 139031.0 177492.0 110123.0 137567.0 123515.0 106978.0 99911.0 True False 139585.16829677537 176039.8394183926 154262.54421915679 131241.54381458354 142713.7167369833 104347.95601953813 124535.65786116908 120272.86212496017 108542.35086750763 118024.07340495908 1.1826838734656853 1.4915587501744016 1.3070430444292314 1.1119896138838832 1.2091915879509614 0.8841243401378289 1.0551716634441834 1.0190536443551235 0.9196628089176504 1.0 16.8487216309706 -6.152534518970742 1.2002228608730885 0.984125253422979 1.3510426211983708 0.6661376898154112 0.10165429184538337 0.2680400961891402 0.7897910520534432 0.03919003681567004 0.06405237301856508 7.038262835819673e-07 6.152534518970742 0.36691736777539186 RAPS(ph)PVVSPTEMNK ddPTM_PC-9_Lapatinib_30min_R1 2 RAPSPVVSPTEMNK 14 1 Q9UPX8;Q9UPX8-3;H7C1X5;E7EUA2;A6NHU9;A0A0A0MSQ6;A0A590UJ45;Q9UPX8-4 Q9UPX8 SHANK2 SH3 and multiple ankyrin repeat domains protein 2 1 RAPS(0.999)PVVS(0.001)PTEMNK;RAPS(0.993)PVVS(0.007)PTEMNK 69.188 0.011273 24658000.0 56336.0 85206.0 79156.0 82688.0 88423.0 65664.0 65189.0 81228.0 75468.0 61321.0 True False 55532.63830924292 85008.71074204119 72648.09923099614 88769.15135908169 83222.13298630659 62855.703790260275 68564.1674477733 85002.14941739301 66967.99912672884 71920.25314490362 0.7721418638134764 1.1819856997828857 1.0101201824835915 1.234271953690586 1.1571446059656123 0.8739638841873895 0.9533360138434367 1.181894469227357 0.9311424278749817 1.0 16.134110478408683 -6.7387798859671735 24.999896811274446 0.9972649395856329 1.0829650056793665 0.07612436633231834 0.13989981612048633 661.909711470651 730274.1326549255 0.046000338452499775 0.04596793713969797 1.824820344031512e-07 6.7387798859671735 0.0857000660937336 RAPS(ph)T(ph)SPSFEGTQETYTVAHEENVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RAPSTSPSFEGTQETYTVAHEENVR 25 1 Q9BUT9 Q9BUT9 FAM195A Protein FAM195A 2 RAPS(0.53)T(0.53)S(0.53)PS(0.401)FEGT(0.01)QETYTVAHEENVR 64.256 0.011242 0.0 2839.8 4138.5 3084.1 2903.9 3913.4 2682.1 2804.1 2627.7 3249.3 2054.5 True False 3320.522051393344 4549.342929606331 3157.6366405143826 2741.2038975708256 3146.5973625769566 2541.4459544327983 2538.4753480740596 2558.7256592782874 3296.8148654283377 2426.964586586948 1.3681790289585603 1.8744990984825594 1.3010641597185324 1.1294783256091074 1.2965155651496472 1.0471705967522362 1.0459465960498129 1.0542904801411361 1.3584107834324293 1.0 11.244937342006454 -5.475148167562847 5.259002060968258 1.1393232849400183 1.6210034054736957 0.6026794746753614 0.15676628075160665 0.12338237769839985 7.889647599244234 0.03981328910815673 0.08244223200691427 3.348511790197846e-06 5.475148167562847 0.48168012053367737 RAPS(ph)VANVGSHCDLSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RAPSVANVGSHCDLSLK 17 1 Q60FE5;P21333-2;P21333 Q60FE5 FLNA Filamin-A 1 RAPS(0.999)VANVGS(0.001)HCDLSLK 69.188 0.0075238 51922000.0 33081.0 47796.0 47580.0 42142.0 52250.0 34504.0 32642.0 41201.0 30320.0 16702.0 True False 38680.959920467336 52540.87100724031 48714.48764815484 39780.920366207385 42011.98757976339 32694.54949917948 29549.91345238525 40119.51740606796 30763.37264019548 19729.940387040737 1.9605208714099431 2.663002015036541 2.469064107266745 2.0162716960025273 2.1293519775335064 1.6571033088703258 1.4977193479912687 2.0334332805394464 1.559222787130257 1.0 14.268098976591629 -7.5248517317551995 0.2023255305266098 0.7620634754330495 2.8161509396763718 0.6860897852344217 0.25921705382397986 1.8888901849216435 0.33224855906540757 1.1165756099691877 1.5362391284760735 2.986402003290265e-08 7.5248517317551995 2.054087464243322 RAPSTSPS(ph)FEGTQETYTVAHEENVR ddPTM_PC-9_AZD4547_30min_R2 3 RAPSTSPSFEGTQETYTVAHEENVR 25 1 Q9BUT9 Q9BUT9 FAM195A Protein FAM195A 1 RAPS(0.02)T(0.02)S(0.02)PS(0.863)FEGT(0.077)QET(0.001)YTVAHEENVR;RAPS(0.057)T(0.057)S(0.057)PS(0.802)FEGT(0.022)QET(0.002)Y(0.001)TVAHEENVR;RAPS(0.109)T(0.109)S(0.109)PS(0.494)FEGT(0.178)QET(0.001)YTVAHEENVR 88.045 2.9917e-06 59068000.0 11026.1 7325.7 33073.3 31547.8 33280.3 18731.0 23707.1 44520.7 37027.0 28948.3 True False 14532.170442872668 9693.589263128575 32634.726432289663 24274.942118651248 28659.904804793696 17559.747608947753 25816.985973261868 37641.04879890956 38984.17162788131 27934.828828176764 0.520216913884027 0.34700729053156154 1.168245083333831 0.8689848170526847 1.0259559842330437 0.6285969288358741 0.9241862956117809 1.3474594396276565 1.3955400216578207 1.0 14.769777359694725 -4.85518166918004 0.4043435799495418 1.1701984878768297 1.6697236128049606e-15 0.44941726410165395 0.24200609023591443 5.519584297080512 0.7443348093078171 0.21677201193734533 3.1317847916365302 1.3957843701109011e-05 4.85518166918004 -1.170198487876828 RAPSTSPS(ph)FEGTQETYTVAHEENVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RAPSTSPSFEGTQETYTVAHEENVR 25 1 Q9BUT9 Q9BUT9 FAM195A Protein FAM195A 1 RAPS(0.086)T(0.086)S(0.086)PS(0.355)FEGT(0.355)QET(0.028)Y(0.004)T(0.001)VAHEENVR;RAPS(0.012)T(0.012)S(0.012)PS(0.943)FEGT(0.02)QETYTVAHEENVR;RAPS(0.133)T(0.133)S(0.133)PS(0.601)FEGT(0.001)QETYTVAHEENVR;RAPS(0.013)T(0.013)S(0.058)PS(0.83)FEGT(0.083)QET(0.002)YTVAHEENVR 114.19 4.5525e-09 67060000.0 32639.0 22818.6 39175.6 48049.299999999996 54218.7 54772.0 55576.8 56031.5 56209.9 43765.1 True False 38164.13805036529 25083.879805126257 40109.69487829037 45357.25349893238 43594.93494719456 51899.65989940466 50312.16316281247 54560.7324952816 57031.86344881673 51699.366185659026 0.738193538259502 0.4851873757029601 0.7758256597237834 0.8773270708203403 0.8432392534685934 1.0038742005661414 0.973167891113695 1.055346255103922 1.1031443450197826 1.0 15.657858973311871 -5.997397254457142 0.7305190969255966 1.0503559780458687 0.5758571390541622 0.7921165979601089 0.0798687822307465 0.36265094763067784 0.3796443278940635 0.042786078780484765 0.10931433033524272 1.0060110372993034e-06 5.997397254457142 -0.4744988389917064 RAPSTSPS(ph)FEGTQETYTVAHEENVR ddPTM_PC-9_Lapatinib_30min_R1 2 RAPSTSPSFEGTQETYTVAHEENVR 25 1 Q9BUT9 Q9BUT9 FAM195A Protein FAM195A 1 RAPS(0.137)T(0.137)S(0.137)PS(0.576)FEGT(0.012)QET(0.001)YTVAHEENVR;RAPS(0.108)T(0.108)S(0.108)PS(0.465)FEGT(0.157)QET(0.041)Y(0.01)T(0.003)VAHEENVR 69.398 0.00020115 35078000.0 18654.7 13996.1 34602.0 19119.8 30406.3 28703.0 16539.9 23945.5 27817.6 21934.6 True False 18388.680557147003 13963.69289036782 31757.1571275826 20525.933873783055 28617.861215085843 27475.439599961013 17396.255091647745 25058.09534734553 24684.48895568572 25725.966383982686 0.7147906625811355 0.5427859417192503 1.2344398128171001 0.7978683314521767 1.112411514029797 1.0680041787299999 0.6762138623674356 0.9740390301896305 0.9595164895750854 1.0 14.650937651855978 -5.240683417476189 24.88394119096334 0.967714891171442 0.6287882523113806 0.4556232443019731 0.15228275249106307 685.4666161970423 821790.2842130256 0.03773762312904421 0.09960857835420195 5.745351216843155e-06 5.240683417476189 -0.33892663886006147 RAPSVANVGS(ph)HCDLSLK ddPTM_PC-9_AZD4547_30min_R2 1 RAPSVANVGSHCDLSLK 17 1 Q60FE5;P21333-2;P21333 Q60FE5 FLNA Filamin-A 1 RAPS(0.333)VANVGS(0.659)HCDLS(0.009)LK 51.591 0.026951999999999997 33993000.0 38094.0 36452.0 44062.0 40309.0 35402.0 39496.0 32931.0 42047.0 30982.0 36045.0 True False 50207.099595576976 48234.39614228854 43477.70909040064 31016.382817841928 30487.043383001543 37026.30887635471 35861.79520419986 35549.60229393856 32619.645268993423 34783.07552124412 1.4434347406948667 1.386720277591005 1.2499673602423738 0.8917090381757171 0.8764907336725088 1.0644920933958388 1.031012774655217 1.022037348946509 0.9378022150189289 1.0 15.08609788100015 -5.570635211262179 3.539299629590995 0.9783148732998357 1.403684552957868 0.8994939541898657 0.060440491449660655 0.07149327378901336 1.8449423645493144 0.018815516687843762 0.03667629551853545 2.687600967375959e-06 5.570635211262179 0.4253696796580324 RAQCETLS(ph)PDGLPEEQPQTTK ddPTM_PC-9_AZD4547_30min_R2 2 RAQCETLSPDGLPEEQPQTTK 21 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659;A0A087X146 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 RAQCET(0.009)LS(0.991)PDGLPEEQPQTTK;RAQCET(0.016)LS(0.984)PDGLPEEQPQTTK 84.31200000000001 0.00021438 16754200.0 63504.0 50487.0 69317.0 91569.0 72490.0 68841.0 67651.0 77282.0 63770.0 69848.0 True False 83696.95103474359 66805.93542290476 68397.81128907684 70459.18177694731 62426.01476848154 64536.3613874097 73671.8079426476 65339.84266368957 67140.75201096464 67402.64278007671 1.2417458364033649 0.9911471222409052 1.0147645324864663 1.0453474651853571 0.9261656842175602 0.9574752372541356 1.0930106729349782 0.9693958570271836 0.9961145326309152 1.0 16.040517538478298 -4.760229566074632 24.999084466730427 0.9995756976266618 1.2417461266923715 0.7336417884703266 0.04383076128593452 15.853934995691915 327463.5793670618 0.011045470179036824 0.0664222342065397 1.7368824779275605e-05 4.760229566074632 0.24217042906570974 RAQCETLS(ph)PDGLPEEQPQTTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RAQCETLSPDGLPEEQPQTTK 21 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659;A0A087X146 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 RAQCET(0.001)LS(0.999)PDGLPEEQPQTTK;RAQCET(0.003)LS(0.997)PDGLPEEQPQTTK 95.51899999999999 0.00015861 11593600.0 33011.0 22744.0 26288.0 37178.0 39206.0 50811.0 43549.0 38815.0 39550.0 36858.0 True False 38599.11030303036 25001.874010140473 26914.805617795162 35095.03719270226 31523.865742625898 48146.381712346614 39423.72345254349 37796.147377892 40128.34392875104 43540.06363223255 0.8865193819895012 0.5742268596877216 0.6181618346986114 0.8060400988188159 0.7240197444104995 1.1057949322036364 0.9054585630728902 0.8680774492463453 0.9216418301016026 1.0 15.410055895523875 -6.672931253243211 9.301053066642272 0.9482888127030443 0.7114621893499825 0.5761579893614992 0.10181764229508934 0.2304522409365407 22.056012342421646 0.03414488388366568 0.034117457655202105 2.1235805881316862e-07 6.672931253243211 -0.23682662335306182 RAQCETLS(ph)PDGLPEEQPQTTK ddPTM_PC-9_Lapatinib_30min_R1 2 RAQCETLSPDGLPEEQPQTTK 21 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659;A0A087X146 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 RAQCET(0.001)LS(0.999)PDGLPEEQPQTTK;RAQCET(0.02)LS(0.98)PDGLPEEQPQTTK 105.04 4.0258e-05 12181300.0 44890.0 34371.0 46570.0 34641.0 42301.0 52588.0 40510.0 39757.0 48071.0 34433.0 True False 44249.86036818223 34291.41606124797 42741.1943653986 37188.61469898843 39812.9383469658 50338.93382861545 42607.4095830477 41604.255360064155 42656.737769928695 40384.698170911506 1.095708582020671 0.8491190380109752 1.0583512147228191 0.9208590476918516 0.985842166715572 1.2464853300519114 1.0550384554746328 1.0301984970641944 1.0562599128363352 1.0 15.301521136518925 -6.559522497080376 24.99905592434077 1.0823062039205629 0.9741425037202605 0.2240191702786749 0.08843396476260551 231.82840275123934 158156.18256750485 0.028067365642816856 0.02806743687065637 2.7572586186747303e-07 6.559522497080376 -0.10816370020030242 RAQEQS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RAQEQSPR 8 1 K7EPU6;K7EMM8;Q49A26-4;Q49A26-2;Q49A26-3;Q49A26 K7EPU6 GLYR1 Putative oxidoreductase GLYR1 1 RAQEQS(1)PR 63.184 0.045385 0.0 2275.4 1317.1 2582.1 3549.2 1979.2 2251.7 2708.0 2835.5 2553.6 1964.8 True False 2660.580278801471 1447.8529835893428 2643.667056668781 3350.3498306616516 1591.389967806079 2133.6168881086946 2451.478635777808 2761.0711294605903 2590.941569063429 2321.0026866517574 1.1463064192483048 0.6238049580537078 1.139019386695538 1.4434924396812374 0.685647619866306 0.9192651522461689 1.0562153373955259 1.189602728742925 1.1163027013988862 1.0 11.180532477321615 -7.520888205771002 23.707161624716317 1.116353469510095 0.9891688599143742 0.04505474033568335 0.22426844333983129 135.69647528741328 1616272.8229491902 0.106815918411209 0.06303534012272935 3.0137817191505454e-08 7.520888205771002 -0.12718460959572075 RAQQQAEAER ddPTM_PC-9_AZD4547_30min_R2 1 RAQQQAEAER 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 139.31 7.6476e-05 2062100.0 7914.3 4933.1 9464.7 12408.0 13273.0 11382.0 8394.7 7178.9 9722.0 13532.0 False True 10430.882772333573 6527.628102971671 9339.191893874875 9547.527301689011 11430.273058657123 10670.281740699555 9141.812037311238 6069.56595971069 10235.885072143627 13058.248798820245 0.7987964491284587 0.49988541369815326 0.7151948195931624 0.7311491340670112 0.8753297042165255 0.8171296094207952 0.7000794806526554 0.4648070390770199 0.7838635355966256 1.0 13.672673814055754 -5.50678421302061 23.636585840514574 0.7469525428581245 0.6388907354168865 0.08223519628844211 0.14620061119069358 903.0346686384233 1326199.469510246 0.0389948615888137 0.07752135120039827 3.1132628331821384e-06 5.50678421302061 -0.10806180744123806 RAQQQAEAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RAQQQAEAER 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ;; 157.78 7.2025e-05 3796940.0 10062.8 9794.57 13176.48 12083.910000000002 24130.8 17868.0 12169.92 17034.2 15249.0 12659.0 False True 11766.23329064052 10766.910179541925 13490.657255278677 11406.8876992648 19402.542964397195 16930.970625183712 11017.097075009262 16587.070299226794 15471.987776726275 14953.976491411135 0.7868297303662671 0.7200031500468076 0.9021451426667068 0.7627996276319133 1.2974838482286708 1.1322052455350635 0.7367336093738657 1.109207996197776 1.0346403704467946 1.0 13.868241549699338 -6.2140218412941985 24.999016873619016 1.04544822032122 0.7955342584131309 0.4567613320162962 0.13813737321848932 408.3474296178663 215284.7792023911 0.042334796876876746 0.054653832866332464 6.109113005249333e-07 6.2140218412941985 -0.24991396190808923 RAQQQAEAER ddPTM_PC-9_Lapatinib_30min_R1 2 RAQQQAEAER 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 133.42 7.2025e-05 1864120.0 6185.66 6383.700000000001 10126.2 8378.7 8723.1 6992.900000000001 7785.57 6508.32 10717.099999999999 5666.96 False True 6097.45135408888 6368.918934863357 9293.66292426239 8994.897548523835 8210.02440827445 6693.829968246081 8188.66871951342 6810.720306990283 9510.027341933861 6646.486485250452 0.9173946817796196 0.9582384541060818 1.3982820765356883 1.3533312026564501 1.2352427747342485 1.0071230842191121 1.2320296953413359 1.0247098707120357 1.4308352786149547 1.0 12.698376178680888 -5.129657804646388 7.4214509911102775 1.2103004838828966 0.9282244620959517 0.34574531317461443 0.1502420030584666 0.2725086335716524 14.933753338674313 0.03810109247273394 0.10253240231319725 7.418945749632957e-06 5.129657804646388 -0.2820760217869449 RAQS(ph)TDSLGTSGSLQSK ddPTM_PC-9_AZD4547_30min_R2 1 RAQSTDSLGTSGSLQSK 17 1 I3L456;Q15276-2;Q15276 I3L456 RABEP1 Rab GTPase-binding effector protein 1 1 RAQS(0.742)T(0.217)DS(0.039)LGT(0.001)S(0.001)GSLQSK 53.255 0.028651 14480000.0 32999.0 19904.0 38365.0 67568.0 49223.0 40720.0 28320.0 47658.0 30849.0 38349.0 True False 43491.99557816048 26337.578756065814 37856.25503275432 51991.24151519371 42389.236100827184 38173.771962861145 30840.425136890477 40293.5511718915 32479.615160518293 37006.41318252716 1.175255633763921 0.7117030938978244 1.0229647181972346 1.4049251749624236 1.1454564886294238 1.0315447696748183 0.8333805544670295 1.0888261711058338 0.8776753099609711 1.0 15.175487689882297 -7.006970752960049 23.453233537202646 0.953814108354669 1.0848755014785485 0.1300577561215739 0.17263364676816154 359.8363350602739 1210682.190847168 0.06706068380593966 0.05683046512037661 9.840773750378595e-08 7.006970752960049 0.13106139312387954 RAQS(ph)TDSLGTSGSLQSK ddPTM_PC-9_Lapatinib_30min_R1 2 RAQSTDSLGTSGSLQSK 17 1 I3L456;Q15276-2;Q15276 I3L456 RABEP1 Rab GTPase-binding effector protein 1 1 RAQS(0.848)T(0.142)DS(0.006)LGT(0.001)S(0.002)GSLQSK;RAQS(0.987)T(0.013)DSLGTSGSLQSK 127.88 4.9106999999999996e-05 19254700.0 96413.0 50389.0 69764.0 54534.0 61989.0 58891.0 41503.0 42186.0 66649.0 53547.0 True False 95038.13294002107 50272.32736639094 64028.27321682777 58544.61228009109 58342.92889506307 56372.36921162607 43651.82226426139 44146.11556756461 59142.28777491583 62802.52760310743 1.5132851585310818 0.8004825487932034 1.0195174567091738 0.9322015293727499 0.9289901397563544 0.8976130637270211 0.6950647359311304 0.7029353316247782 0.94171827205231 1.0 15.938535003747342 -4.757495209928956 24.999985463010706 0.8728715872309264 1.5132860816428868 0.7575769323637176 0.10743455938577678 59.12901858058139 374735.11490183964 0.028537101425626307 0.21092545440815874 1.7478525403322165e-05 4.757495209928956 0.6404144944119604 RAQST(ph)DSLGTSGSLQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RAQSTDSLGTSGSLQSK 17 1 I3L456;Q15276-2;Q15276 I3L456 RABEP1 Rab GTPase-binding effector protein 1 1 RAQS(0.373)T(0.619)DS(0.006)LGT(0.002)SGSLQSK 60.032 0.031303 10417000.0 15800.0 11781.0 14715.0 30541.0 30357.0 37857.0 32200.0 40179.0 38200.0 27412.0 True False 18474.62793577534 12950.539822083405 15065.861406948261 28829.886785257964 24408.763769547866 35871.71227656033 29149.78289218811 39124.34382316946 38758.6027327001 32381.578606727384 0.5705289467245792 0.39993540708336206 0.4652602515128239 0.8903175208162476 0.7537854798862975 1.1077814553830263 0.9001964742426777 1.2082284282163207 1.196933701207756 1.0 14.982885698500096 -6.179356216023431 0.8667442108884121 1.1149011188508728 0.4262706632542316 0.7993869466248399 0.1250692852512459 0.26440217708140434 0.4193887853513622 0.06138900465687102 0.11243166424591224 6.616735646951239e-07 6.179356216023431 -0.6886304555966413 RAQST(ph)DSLGTSGSLQSK ddPTM_PC-9_Lapatinib_30min_R1 1 RAQSTDSLGTSGSLQSK 17 1 I3L456;Q15276-2;Q15276 I3L456 RABEP1 Rab GTPase-binding effector protein 1 1 RAQS(0.376)T(0.586)DS(0.036)LGT(0.002)S(0.001)GSLQSK 81.37899999999999 0.0043614 14237000.0 76687.0 34979.0 43311.0 35927.0 37563.0 36315.0 32877.0 31650.0 50389.0 26375.0 True False 75593.42931732665 34898.00827460337 39750.1367652948 38569.19142895867 35353.618191699396 34761.892104399674 34579.210191603546 33120.57454400557 44713.660200306585 30933.883607521602 2.4437096316915743 1.1281483022751755 1.2850031140490075 1.2468266810049204 1.1428768091408714 1.123748073324595 1.1178425130944625 1.0706891822645983 1.4454589914288816 1.0 14.916900348107266 -4.760094463570829 24.999420534250376 1.177148910373009 2.443711164965591 0.9114195900593829 0.11880146894615266 8.724127134741588 162104.43748916814 0.028344183070718634 0.1719512452010166 1.737422880083951e-05 4.760094463570829 1.2665622545925819 RAQT(ph)PPISSLPTSPSDEVGR ddPTM_PC-9_AZD4547_30min_R2 1 RAQTPPISSLPTSPSDEVGR 20 1 Q15751 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 RAQT(0.996)PPIS(0.002)S(0.002)LPTSPSDEVGR 84.947 0.00066486 6578500.0 12046.0 11306.0 17578.0 22908.0 16716.0 14062.0 13515.0 16576.0 12356.0 15163.0 True False 15876.377427634809 14960.443399119773 17344.904234738842 17626.914525071887 14395.271939163145 13182.700917037171 14717.808817975803 14014.560078586475 13009.112934726047 14632.147985258005 1.085033956985015 1.0224365837601237 1.1853969938121156 1.2046703288424319 0.9838112595407377 0.9009409233913461 1.0058542896643816 0.9577923960792527 0.8890774579257141 1.0 13.836853950817485 -6.41025631581364 5.986761877597862 0.9506397773212579 1.1206831119782208 0.6680725753080202 0.058376454719407576 0.15223498493367735 7.052366710583721 0.019357756884224763 0.021918675791322065 3.888156025836187e-07 6.41025631581364 0.17004333465696286 RAQT(ph)PPISSLPTSPSDEVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RAQTPPISSLPTSPSDEVGR 20 1 Q15751 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 RAQT(1)PPISSLPTSPSDEVGR 96.53299999999999 0.00041279 5044000.0 34501.0 31220.0 52179.0 42639.0 44246.0 35099.0 32680.0 31422.0 33065.0 26566.0 True False 40341.337874188925 34319.31527420798 53423.145249959474 40250.075067503145 35576.313922568625 33258.34665174183 29584.31381728908 30597.205794360998 33548.51307216568 31382.205503659698 1.2854844720676002 1.0935915664119198 1.7023387742371845 1.2825763652210265 1.1336460695351644 1.0597835976780963 0.9427098364338684 0.9749858336372453 1.0690298063421118 1.0 14.937659126290798 -6.4392259100584 2.2825113106785335 1.003033364356044 1.35121138075964 0.5434487059960613 0.14413812479465424 0.2470287789955421 2.5420860250635937 0.0521917703033874 0.0592641320718559 3.637257850734239e-07 6.4392259100584 0.3481780164035959 RAQT(ph)PPISSLPTSPSDEVGR ddPTM_PC-9_Lapatinib_30min_R1 2 RAQTPPISSLPTSPSDEVGR 20 1 Q15751 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 RAQT(1)PPISSLPTSPSDEVGR;RAQT(1)PPISSLPTSPSDEVGR 120.42 9.8556e-06 16472900.0 95524.0 79976.0 93918.0 71389.0 74933.0 70790.0 52425.0 61624.0 82279.0 47347.0 True False 94161.8102430439 79790.82048571073 86196.42457396409 76639.18520672277 70525.58826394615 67762.47671954987 55139.309982504936 64487.27600947235 73011.8725837191 55530.86586408816 1.695666162913883 1.4368733360109822 1.552225473755981 1.3801186783994552 1.2700250062110967 1.220266885184153 0.9929488605032459 1.1612870609168062 1.3147980217419213 1.0 15.761002270852533 -6.117622754055495 0.9695060559031226 1.1261183830759303 1.596724825972421 0.7650452990132173 0.10353771374851949 0.28725578882673447 0.5604602432070761 0.04651649858375776 0.08722758638787048 7.627412706052334e-07 6.117622754055495 0.4706064428964907 RAQVLATIHGHAGAFPAAGDAGEGAPGGGS(ph)SPER ddPTM_PC-9_AZD4547_30min_R2 2 RAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPER 34 1 Q86WR7;D3DRR9 Q86WR7 PROSER2;C10orf47 Proline and serine-rich protein 2 1 RAQVLATIHGHAGAFPAAGDAGEGAPGGGS(0.5)S(0.5)PER;RAQVLATIHGHAGAFPAAGDAGEGAPGGGS(0.5)S(0.5)PER 49.663999999999994 0.0025174 33502000.0 12798.3 9368.5 23245.0 30648.0 29931.0 22810.8 22604.0 26792.0 18519.5 23677.6 True False 16867.89317882272 12396.684413997316 22936.756111986826 23582.577106879824 25775.597296667373 21384.437070000826 24615.71221024973 22651.91201891221 19498.402961691416 22848.654430900537 0.7382444874307595 0.5425564315608902 1.0038558805006539 1.0321210458234569 1.128101323192513 0.9359166919291535 1.0773374985688182 0.991389321739566 0.8533720451967518 1.0 14.479821586275843 -5.271444819461281 24.780722818552498 1.0082552775087141 0.6404004615908822 0.754052321680774 0.08273183995395353 238.4060650391049 590467.0844430008 0.02121608923886741 0.04502815996325307 5.352481569502674e-06 5.271444819461281 -0.367854815917832 RAS(ph)AAAAAGGGATGHPGGGQGAENPAGLK ddPTM_PC-9_AZD4547_30min_R2 5 RASAAAAAGGGATGHPGGGQGAENPAGLK 29 1 Q07617 Q07617 SPAG1 Sperm-associated antigen 1 1 RAS(1)AAAAAGGGATGHPGGGQGAENPAGLK;RAS(1)AAAAAGGGATGHPGGGQGAENPAGLK;RAS(0.86)AAAAAGGGAT(0.14)GHPGGGQGAENPAGLK;RAS(0.938)AAAAAGGGAT(0.062)GHPGGGQGAENPAGLK;RAS(1)AAAAAGGGATGHPGGGQGAENPAGLK 104.38 1.1851999999999999e-11 55990500.0 132124.4 114120.2 135333.8 175872.1 185153.1 126669.20000000001 117863.00000000001 183643.1 134836.4 155996.3 True False 174137.21084175564 151007.3229078567 133539.185386466 135327.50454185868 159447.788040145 118748.554899756 128352.57866911455 155265.27859362087 141963.57683003347 150534.91701857798 1.156789496354954 1.0031381814839704 0.8870977447045427 0.898977507824032 1.0592079977063864 0.788843925725889 0.852643235278591 1.0314236834133246 0.9430607837815682 1.0 17.199738637613308 -4.838933787221439 2.907162327452897 0.9293795654999109 1.1811086381133493 0.42994978159241115 0.07818379484885284 0.3343321161815238 4.364983450768172 0.02045615029825148 0.18800658998408487 1.4489927509469878e-05 4.838933787221439 0.25172907261343846 RAS(ph)AAAAAGGGATGHPGGGQGAENPAGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RASAAAAAGGGATGHPGGGQGAENPAGLK 29 1 Q07617 Q07617 SPAG1 Sperm-associated antigen 1 1 RAS(0.814)AAAAAGGGAT(0.186)GHPGGGQGAENPAGLK;RAS(0.991)AAAAAGGGAT(0.009)GHPGGGQGAENPAGLK;RAS(0.698)AAAAAGGGAT(0.302)GHPGGGQGAENPAGLK;RAS(1)AAAAAGGGATGHPGGGQGAENPAGLK 94.031 4.1028e-05 37769900.0 58208.7 44616.1 44736.899999999994 48387.1 61060.0 41050.1 40114.1 51440.5 34079.2 31072.9 True False 68062.2832357699 49045.29155046731 45803.59736163806 45676.12766009476 49095.73132287755 38897.36049142904 36314.202047065926 50090.24138071503 34577.54382848781 36706.17079705895 1.8542463503499889 1.336159301977558 1.2478446094221312 1.2443719044579427 1.3375334516454467 1.0596954039822006 0.9893214480976471 1.3646272627470166 0.942009015858944 1.0 15.163734999292386 -1.5228787452813703 0.7093166104939507 1.1260135203214356 94.14096577744665 0.7201895104822804 0.13520984650232407 161.94625206789703 0.8277754936309436 0.05165418157762 23927.02556658146 0.029999999999928657 1.5228787452813703 93.01495225712522 RAS(ph)AAAAAGGGATGHPGGGQGAENPAGLK ddPTM_PC-9_Lapatinib_30min_R1 3 RASAAAAAGGGATGHPGGGQGAENPAGLK 29 1 Q07617 Q07617 SPAG1 Sperm-associated antigen 1 1 RAS(0.988)AAAAAGGGAT(0.012)GHPGGGQGAENPAGLK;RAS(1)AAAAAGGGATGHPGGGQGAENPAGLK;RAS(0.996)AAAAAGGGAT(0.004)GHPGGGQGAENPAGLK 87.37200000000001 1.9363e-08 34406200.0 74787.6 65898.8 58778.3 44790.7 49567.1 36829.2 36321.299999999996 33737.700000000004 56164.600000000006 44149.0 True False 73721.115109634 65746.21537741013 53945.77506479938 48084.75749539508 46651.66063066805 35254.10096905841 38201.83919251419 35305.27670752917 49838.7513085423 51780.0958251553 1.4237346210900508 1.2697198475532745 1.0418245506334496 0.9286339997855897 0.9009574024002519 0.6808427139281501 0.7377707318563004 0.6818310423129326 0.9625079002717898 1.0 15.66011001466674 -5.26707620355107 0.9794484239547445 0.7948232613144877 1.5304059965563246 0.7949241763908543 0.1040934350295812 0.4279640242499351 0.5433540475129325 0.03702524763408602 0.2824001606965729 5.406594477252831e-06 5.26707620355107 0.7355827352418369 RAS(ph)AGPAPGPVVTAEGLHPSLPS(ph)PTGNSTPLGSSK ddPTM_PC-9_AZD4547_30min_R2 1 RASAGPAPGPVVTAEGLHPSLPSPTGNSTPLGSSK 35 1 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 2 RAS(0.952)AGPAPGPVVT(0.088)AEGLHPS(0.191)LPS(0.579)PT(0.064)GNS(0.095)T(0.031)PLGSSK 54.997 0.00023996 5459600.0 9153.8 9407.6 28219.0 67998.0 58809.0 41358.0 16656.0 54982.0 31822.0 47808.0 True False 12064.517989131959 12448.422724355134 27844.79762203294 52322.11165862749 50644.38546723172 38771.87772200423 18138.351733052525 46485.795260668514 33504.04595409943 46134.256471622684 0.2615088854104082 0.2698303533300075 0.6035601254170067 1.1341271250531797 1.0977609555360066 0.8404140586042159 0.39316449684649146 1.0076199079801376 0.7262292386723055 1.0 15.493550785051003 -5.448269621810915 3.6209730838667156 0.8731561348999923 0.27187410797276973 0.5957309873486298 0.20319579788491582 0.17217730602904913 4.295829166544576 0.05889159165373726 0.13005688263936085 3.5622990755910785e-06 5.448269621810915 -0.6012820269272225 RAS(ph)AGPAPGPVVTAEGLHPSLPSPTGNSTPLGSSK ddPTM_PC-9_AZD4547_30min_R2 3 RASAGPAPGPVVTAEGLHPSLPSPTGNSTPLGSSK 35 1 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 RAS(0.996)AGPAPGPVVT(0.003)AEGLHPS(0.001)LPSPTGNSTPLGSSK;RAS(0.962)AGPAPGPVVT(0.038)AEGLHPSLPSPTGNSTPLGSSK;RAS(0.991)AGPAPGPVVTAEGLHPS(0.004)LPS(0.001)PT(0.001)GNS(0.002)T(0.001)PLGSSK 95.926 3.4173e-16 64956000.0 38069.9 43659.1 259968.8 624206.0 402364.0 282219.0 117615.1 411519.0 172517.7 298685.8 True False 50175.336296888134 57771.050274766494 256521.4438514039 480304.95058656484 346502.70390819863 264571.8013159805 128082.61604936041 347928.19431586785 181636.63342013524 288228.90105488244 0.17408155848789816 0.20043462006527288 0.8899920962560203 1.666401075078549 1.2021789023933451 0.9179225273651606 0.44437811607577776 1.2071245910541701 0.6301818893086968 1.0 18.136855477951073 -5.2893627961269924 4.682283239305535 1.0165699069208556 0.1758578315477201 0.5163879091295431 0.313761263662392 0.15052281037729334 8.618773596815876 0.08808312911922567 0.20708275335529008 5.136144147855002e-06 5.2893627961269924 -0.8407120753731354 RAS(ph)AGPAPGPVVTAEGLHPSLPSPTGNSTPLGSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RASAGPAPGPVVTAEGLHPSLPSPTGNSTPLGSSK 35 1 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 RAS(0.923)AGPAPGPVVT(0.045)AEGLHPS(0.018)LPS(0.004)PT(0.003)GNS(0.004)T(0.004)PLGSSK 48.12 0.0027946 18918000.0 13439.0 14881.0 52764.0 49138.0 75476.0 61745.0 36771.0 34968.0 43174.0 20799.0 True False 15713.957267650945 16358.28733489713 54022.09386858431 46384.957167545435 60687.01960899938 58506.98350413971 33287.78468101394 34050.12705165856 43805.33807281659 24569.6940552066 0.6395666642141593 0.6657912507229865 2.1987287976480276 1.887893152569229 2.469994924342133 2.381266261300531 1.3548310616411552 1.3858588135102539 1.7829012430675233 1.0 14.584592272748742 -5.2503866372648735 24.298734522191463 1.8522952431679816 0.6526786038731203 0.5169959425072395 0.44488728391995686 392.9786540185199 863931.4632770071 0.11904780400494695 0.30814302238816754 5.618409150585225e-06 5.2503866372648735 -1.1996166392948613 RAS(ph)AGPAPGPVVTAEGLHPSLPSPTGNSTPLGSSK ddPTM_PC-9_Lapatinib_30min_R1 2 RASAGPAPGPVVTAEGLHPSLPSPTGNSTPLGSSK 35 1 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 RAS(0.998)AGPAPGPVVT(0.001)AEGLHPSLPSPTGNSTPLGSSK;RAS(0.994)AGPAPGPVVT(0.005)AEGLHPS(0.001)LPS(0.001)PTGNSTPLGSSK 70.03399999999999 3.5268000000000003e-06 21267200.0 38510.0 22707.5 112541.0 32403.3 51202.0 70776.0 28572.9 46329.2 99254.0 30869.6 True False 37960.84033813093 22654.922178894638 103288.31340082268 34786.34677624002 48190.399027005136 67749.07546691434 30052.264953726582 48481.82376505982 88074.9693290447 36205.369228843534 1.0484864854765485 0.6257337699195804 2.852845188457201 0.9608062979931432 1.3310290725778195 1.8712438765281545 0.8300499509830992 1.3390782858371202 2.432649388888941 1.0 15.143916043306072 RAS(ph)AILR ddPTM_PC-9_AZD4547_30min_R2 1 RASAILR 7 1 P46779 P46779 RPL28 60S ribosomal protein L28 1 RAS(1)AILR 65.157 0.026382 5921400.0 15087.0 11749.0 14400.0 26852.0 24680.0 11630.0 11659.0 13871.0 10970.0 17929.0 True False 19884.352170905386 15546.634485782615 14209.046591207149 20661.68625926446 21253.60800780968 10902.774261494978 12696.628413524228 11727.555673870233 11549.85180430113 17301.31116716287 1.1492974132876712 0.8985812887574351 0.8212699288465083 1.194226614366629 1.2284391513718391 0.6301704047834228 0.7338535380845512 0.6778420179002745 0.6675708963735791 1.0 14.07859375513888 -6.7718056757129 24.999403988807362 0.7212503538005159 1.043862289935466 0.5187173290301547 0.15144974719133336 176.47884327817215 425594.56160699297 0.05476318057467501 0.048816588055515094 1.6911974856533754e-07 6.7718056757129 0.32261193613495 RAS(ph)AILR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RASAILR 7 1 P46779 P46779 RPL28 60S ribosomal protein L28 1 RAS(1)AILR 62.463 0.030652 4953100.0 12919.0 16917.0 13462.0 15696.0 14668.0 22024.0 9914.1 14682.0 12152.0 11824.0 True False 15105.931538119097 18596.407959441894 13782.985134919296 14816.60400711859 11793.910695119033 20869.022668963837 8974.964676131749 14296.613056864884 12329.700010674658 13967.597601267498 1.0814981909808383 1.3313963138338372 0.9867828046298063 1.060783996653372 0.8443764655740646 1.4941025124513942 0.6425560738746734 1.0235556224477378 0.8827359122628069 1.0 13.769796280984949 -7.283344011280983 24.999946845705868 0.889174925834793 1.119098268668826 0.2775804751913835 0.19357046069996403 1179.7922433188598 1346501.563821221 0.07837450445765641 0.05289058373051011 5.207820282952942e-08 7.283344011280983 0.22992334283403304 RAS(ph)AILR ddPTM_PC-9_Lapatinib_30min_R1 3 RASAILR 7 1 P46779 P46779 RPL28 60S ribosomal protein L28 1 RAS(1)AILR;RAS(1)AILR;RAS(1)AILR 70.908 0.019609 11624000.0 83802.0 75033.0 81890.0 76849.0 78482.0 63848.0 67241.0 57772.0 78718.0 72642.0 True False 82606.96811259516 74859.26569851363 75157.32030454144 82500.73182074887 73865.84306154869 61117.3698769575 70722.40996726019 60456.298027055025 69851.94990271151 85198.07291061939 0.9695872839665923 0.8786497527596414 0.8821481253852816 0.9683403509290606 0.8669895989201627 0.7173562474948845 0.8300940097724334 0.7095970127220981 0.8198771112580518 1.0 16.378533178149212 -6.52824622674692 24.596494533275823 0.7974894244154569 0.9182690290382257 0.27689054872720165 0.0804588777632495 131.40489232431042 602155.7344100169 0.02472860332628802 0.024809013891071777 2.9631509309595945e-07 6.52824622674692 0.12077960462276882 RAS(ph)APHGPLDMAPFAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RASAPHGPLDMAPFAR 16 1 Q8N4B1-2;Q8N4B1;Q8N4B1-4 Q8N4B1-2 FAM109A Sesquipedalian-1 1 RAS(1)APHGPLDMAPFAR 51.727 0.029729000000000002 2125800.0 7918.5 7765.2 9673.5 7881.8 10363.0 8371.4 8167.0 8001.8 7046.5 7781.3 True False 9258.945652496011 8536.077737581023 9904.152926953042 7440.2082991403695 8332.444541417944 7932.389046992551 7393.362636040389 7791.761228607917 7149.541731831709 9191.988093263091 1.0072843392042679 0.9286432544268859 1.0774766923612427 0.8094231871985756 0.9064899189245996 0.8629677243387952 0.8043268290848924 0.8476687686658976 0.7778014570179531 1.0 13.166161213868762 -5.770777517861422 24.999830548534327 0.8519786128910191 0.9968856186016943 0.49163896294892206 0.06772382790001706 150.74197612059672 403563.08153703134 0.018020893432635115 0.027140124767739342 1.6952060050522481e-06 5.770777517861422 0.14490700571067527 RAS(ph)APHGPLDMAPFAR ddPTM_PC-9_Lapatinib_30min_R1 1 RASAPHGPLDMAPFAR 16 1 Q8N4B1-2;Q8N4B1;Q8N4B1-4 Q8N4B1-2 FAM109A Sesquipedalian-1 1 RAS(1)APHGPLDMAPFAR 49.988 0.033497000000000006 2568600.0 13147.0 9436.9 10191.0 8165.1 6925.9 10391.0 5703.5 6255.4 7759.6 7188.5 True False 12959.521369135478 9415.049437851409 9353.135318397612 8765.588691975125 6518.532178843306 9946.601152604071 5998.799322560167 6546.048720460426 6885.632135789539 8431.022646925841 1.5371233018643164 1.116714997946823 1.1093713906471352 1.0396827358981504 0.773160321330666 1.1797621201066097 0.7115150289327566 0.776424046595021 0.8167018906419626 1.0 13.041491919170724 -1.522878745280396 0.4860880906241769 0.849008502592174 19.841330688779127 0.674764616003434 0.13566214795180473 58.299928588297796 0.6431539963916052 0.07604488102853449 1122.4865734891162 0.02999999999999596 1.522878745280396 18.992322186186954 RAS(ph)AYEALEK ddPTM_PC-9_Lapatinib_30min_R1 1 RASAYEALEK 10 1 Q15785 Q15785 TOMM34 Mitochondrial import receptor subunit TOM34 1 RAS(1)AYEALEK 94.67299999999999 0.0093715 0.0 24574.0 34199.0 36067.0 36786.0 37374.0 31297.0 30594.0 30757.0 34370.0 33084.0 True False 24223.570253680333 34119.8143166803 33101.71048264614 39491.36515449867 35175.73480011111 29958.50026687036 32178.007622408306 32186.082503948794 30498.888667854833 38802.52531834103 0.6242781894978991 0.8793194266805278 0.8530813448628753 1.0177524485972578 0.9065321009786025 0.772076044563772 0.829276119490051 0.8294842214492467 0.786002674249625 1.0 15.24386292746934 -4.760067851910307 24.972163487405343 0.8696492455292206 0.6242778875317843 0.4821916095921672 0.07772691454652725 32.08540209366041 583980.0465459508 0.020052196673665347 0.12187783025658498 1.7375293449974714e-05 4.760067851910307 -0.24537135799743637 RAS(ph)DCGLAPHRPR ddPTM_PC-9_Lapatinib_30min_R1 1 RASDCGLAPHRPR 13 2 Q6ZV89;E5RGJ3;E5RGV2;E5RJW5;J3KQT6 Q6ZV89 SH2D5 SH2 domain-containing protein 5 1 RAS(1)DCGLAPHRPR 61.657 0.016802 1208000.0 4974.2 4242.4 4427.7 5288.5 4710.0 4745.8 4465.3 6453.5 5127.9 3075.2 True False 4903.266995843441 4232.57698345228 4063.671597416264 5677.433931918833 4432.967060216284 4542.833197000137 4696.4913851193005 6753.353169660035 4550.341902819109 3606.74422255357 1.3594717821082234 1.1735173669885637 1.1266869361030514 1.574116039728267 1.229077191694439 1.259538496961622 1.3021415147077413 1.872423646631274 1.2616203484475184 1.0 11.816481400624381 -7.5608508918526764 24.999940200032203 1.457669518440921 1.2846782761083413 0.0 0.23459058806234404 388.1035053877336 255513.78541177025 0.10497951450983331 0.060610067935151425 2.7488377611128185e-08 7.5608508918526764 -0.17299124233257968 RAS(ph)DDGKLTDPSK ddPTM_PC-9_Lapatinib_30min_R1 1 RASDDGKLTDPSK 13 2 P04049;P04049-2;A0A0B4J1W9 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 RAS(1)DDGKLTDPSK 51.463 0.031472 28119000.0 111600.0 77008.0 65558.0 82729.0 84418.0 85618.0 65151.0 59229.0 96107.0 77958.0 True False 110008.56353506663 76829.69270735736 60168.074301198176 88813.16663585394 79452.69921217371 81956.31772530614 68524.19999370867 61980.995566095015 85282.41760842378 91432.93642749473 1.2031612221303005 0.8402846469694477 0.6580568956014091 0.971347635830134 0.8689724109996051 0.8963544312097705 0.7494476571694443 0.677884775310101 0.9327319119412922 1.0 16.480426333247877 -7.2239161431777745 22.909603437737356 0.8131731341692052 0.8933270177674425 0.02786865327763488 0.15245154878467246 687.0592167514844 419479.43781469495 0.05841963222145102 0.04524943913626637 5.971505777463901e-08 7.2239161431777745 0.08015388359823727 RAS(ph)DGGANIQLHAQQLLK ddPTM_PC-9_AZD4547_30min_R2 2 RASDGGANIQLHAQQLLK 18 1 H0Y4E8;Q9Y2K2-7;Q9Y2K2;Q9Y2K2-8;H7C3X8 H0Y4E8 SIK3 Serine/threonine-protein kinase SIK3 1 RAS(1)DGGANIQLHAQQLLK;RAS(1)DGGANIQLHAQQLLK 58.79600000000001 0.014034999999999999 48933000.0 54399.0 51886.0 77558.0 102196.0 87670.0 85996.0 78340.0 93662.0 79794.0 83241.0 True False 71696.75043050853 68657.13481396859 76529.53024450301 78636.29111246065 75498.53379435462 80618.65652549645 85312.1082353108 79188.69003864404 84011.74793732032 80326.75792658834 0.8925637269716913 0.8547230908623902 0.9527277363097902 0.9789551220818269 0.9398927050355214 1.0036338899570039 1.0620633825814139 0.9858320201472043 1.045874999886087 1.0 16.293593028532406 -5.603969051440964 0.6437099561911279 1.0236402320624836 0.8403183618276968 0.7349134683113936 0.03134268254818344 0.7347062358277413 0.4527257970247087 0.017540011184141013 0.08667338870187064 2.4890346847824126e-06 5.603969051440964 -0.18332187023478674 RAS(ph)DGGANIQLHAQQLLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RASDGGANIQLHAQQLLK 18 1 H0Y4E8;Q9Y2K2-7;Q9Y2K2;Q9Y2K2-8;H7C3X8 H0Y4E8 SIK3 Serine/threonine-protein kinase SIK3 1 RAS(1)DGGANIQLHAQQLLK;RAS(1)DGGANIQLHAQQLLK 61.181000000000004 0.008859899999999999 23130000.0 151783.0 158954.0 153912.0 170293.0 189661.0 165355.0 171266.0 174513.0 143727.0 137806.0 True False 177476.8640491004 174733.90262961073 157581.84579451042 160752.03530735534 152498.28854288068 156683.49270915907 155042.44462153706 169932.2186618076 145828.7354702298 162789.1369283046 1.0902254744876776 1.073375692793106 0.9680120477812499 0.987486255782249 0.9367841824116544 0.9624935402057291 0.9524127195896411 1.0438793513393276 0.8958136778773851 1.0 17.312644904860633 -5.233050560703135 4.338536010653356 0.9682983907291979 1.0859077169238256 0.601692612795962 0.03698944434996351 0.1271937277924346 5.811799302162434 0.009083925499640011 0.024650963093729533 5.847220066578524e-06 5.233050560703135 0.11760932619462772 RAS(ph)DGGANIQLHAQQLLK ddPTM_PC-9_Lapatinib_30min_R1 2 RASDGGANIQLHAQQLLK 18 1 H0Y4E8;Q9Y2K2-7;Q9Y2K2;Q9Y2K2-8;H7C3X8 H0Y4E8 SIK3 Serine/threonine-protein kinase SIK3 1 RAS(1)DGGANIQLHAQQLLK;RAS(1)DGGANIQLHAQQLLK 131.3 1.8717e-05 30349000.0 104890.0 82769.0 103376.0 86414.0 82566.0 84590.0 75258.0 65773.0 81409.0 67127.0 True False 103394.2493655297 82577.35346581224 94876.8243228999 92769.1738286536 77709.63021100171 80972.2828889211 79154.49099977787 68829.05369614143 72239.86114522527 78729.81250889474 1.3132795070971166 1.0488701907740834 1.2050939955201965 1.1783233170810958 0.9870419823776696 1.0284831159704972 1.00539412552056 0.8742438410908862 0.9175667875122114 1.0 16.26462242207223 -6.466588700357449 0.9171427087139084 0.932547652869034 1.1986730299061996 0.6694187358068775 0.07426668233445435 0.347093914733345 0.6359139032287513 0.03914626139369435 0.04980257936552245 3.415161922541995e-07 6.466588700357449 0.26612537703716566 RAS(ph)DTSLTQGIVAFR ddPTM_PC-9_AZD4547_30min_R2 1 RASDTSLTQGIVAFR 15 1 Q9H0K1 Q9H0K1 SIK2 Serine/threonine-protein kinase SIK2 1 RAS(0.97)DT(0.028)S(0.001)LTQGIVAFR 58.626000000000005 0.026576 13241000.0 21123.0 22661.0 24810.0 34721.0 32323.0 28908.0 26140.0 28044.0 27093.0 28193.0 True False 27839.674614306008 29985.725089992306 24481.00318943398 26716.60988410253 27835.509385592864 27100.378190137275 28466.409360110072 23710.44418701006 28525.080668544255 27205.97165128133 1.0232927892136077 1.102174385621697 0.8998393258371639 0.9820127075977545 1.0231396894174845 0.9961187395731524 1.046329450202503 0.8715161689839283 1.0484860101367046 1.0 14.73163573419064 -5.240095052245002 24.963460129744707 0.9829086719273233 1.062733583129842 0.23456603425860023 0.05729616562345424 1117.3237763892405 1306772.1357326806 0.01397687681326907 0.036904054347108105 5.753140069489402e-06 5.240095052245002 0.07982491120251856 RAS(ph)DTSLTQGIVAFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RASDTSLTQGIVAFR 15 1 Q9H0K1 Q9H0K1 SIK2 Serine/threonine-protein kinase SIK2 1 RAS(0.999)DT(0.001)SLTQGIVAFR;RAS(0.977)DT(0.02)S(0.003)LTQGIVAFR 167.35 4.2811e-05 17688700.0 22473.5 21695.0 21891.0 25742.0 26228.0 27887.0 21726.0 21754.4 22865.0 15258.0 True False 26277.819678142223 23848.73622273995 22412.964462079817 24299.759196690015 21088.81167927337 26424.55662774222 19667.955997381345 21183.37005069209 23199.357368669844 18024.154617738466 1.4579224510358402 1.3231542187986571 1.243496016174989 1.3481774714013723 1.1700305576894476 1.4660635790228131 1.0911999155857846 1.1752767605446794 1.2871259629474219 1.0 14.13764397425006 -12.883679442981027 0.05032796704793309 9.223814772735496e-09 1.891467859664549 0.48783542473357655 0.10262437593366955 348.0294843156396 1.750478413220136 56.829648417947716 18.27240473059897 1.3071353415747621e-13 12.883679442981027 1.891467850440734 RAS(ph)DTSLTQGIVAFR ddPTM_PC-9_Lapatinib_30min_R1 2 RASDTSLTQGIVAFR 15 1 Q9H0K1 Q9H0K1 SIK2 Serine/threonine-protein kinase SIK2 1 RAS(0.997)DT(0.003)SLTQGIVAFR;RAS(0.999)DT(0.001)SLTQGIVAFR 145.79 4.0571e-06 23741000.0 38418.0 40527.0 45299.0 33828.0 35976.0 37411.0 29112.0 30915.0 36634.0 27252.0 True False 37870.15227500165 40433.16222147147 41574.691079196724 36315.8239668999 33859.962411537366 35811.018739300474 30619.27691388999 32351.423760756184 32507.89314687791 31962.471888992564 1.1848317741671166 1.2650198758687403 1.3007345371655836 1.1362019837835688 1.0593662007473919 1.1204082983216732 0.9579758730874268 1.012169017249807 1.0170644266744957 1.0 14.964091366166038 -6.258396238249536 1.2330343050725852 1.00942571982167 1.2545807556375672 0.8104815898700077 0.048197704606172835 0.191860294067763 0.5970161729671533 0.020061138549903993 0.029140076514761384 5.515739688362352e-07 6.258396238249536 0.24515503581589715 RAS(ph)DTSLTQGLK ddPTM_PC-9_AZD4547_30min_R2 2 RASDTSLTQGLK 12 1 A0A0B4J2F2;P57059 A0A0B4J2F2 LOC102724428;SIK1 Serine/threonine-protein kinase SIK1 1 RAS(0.803)DT(0.17)S(0.026)LT(0.001)QGLK;RAS(0.971)DT(0.025)S(0.004)LTQGLK 63.461999999999996 0.021741 8420100.0 50885.0 46933.0 68319.0 89834.0 80205.0 65487.0 65593.0 81103.0 71571.0 64176.0 True False 67065.37152624919 62103.174425162564 67413.0454211584 69124.1592214645 69069.92018907507 61392.087537620064 71430.64992952166 68570.39491153449 75354.09694490768 61929.21777365415 1.082935873199097 1.002808959288719 1.088549925942019 1.1161800795564258 1.1153042565710996 0.9913267072418507 1.1534240621380754 1.1072381886390565 1.2167777933239894 1.0 15.918332603076275 -7.309323936060665 24.99911105310127 1.1282965319278728 1.0688253181259941 0.13628600241644706 0.06381137953604801 737.6285390992692 385091.0133302366 0.025811236078811424 0.017401953851162166 4.905418492327476e-08 7.309323936060665 -0.0594712138018787 RAS(ph)DTSLTQGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RASDTSLTQGLK 12 1 A0A0B4J2F2;P57059 A0A0B4J2F2 LOC102724428;SIK1 Serine/threonine-protein kinase SIK1 1 RAS(0.983)DT(0.013)S(0.002)LT(0.002)QGLK 81.904 0.018231999999999998 0.0 14047.0 12819.0 12996.0 12627.0 15772.0 17660.0 13952.0 17667.0 13076.0 10152.0 True False 16424.879659103568 14091.585602180394 13305.873927604454 11919.550127286337 12681.589820249335 16733.87851134679 12630.365556267354 17203.25996973381 13267.2117626384 11992.477236812218 1.3695985687332062 1.1750354262857998 1.1095183809697484 0.99391892866788 1.057462071416055 1.395364625748909 1.0531907050444147 1.4345042838127327 1.1062945128562134 1.0 13.549842080679904 RAS(ph)DTSLTQGLK ddPTM_PC-9_Lapatinib_30min_R1 2 RASDTSLTQGLK 12 1 A0A0B4J2F2;P57059 A0A0B4J2F2 LOC102724428;SIK1 Serine/threonine-protein kinase SIK1 1 RAS(0.919)DT(0.065)S(0.016)LTQGLK;RAS(0.986)DT(0.01)S(0.003)LT(0.001)QGLK 117.48 0.00092384 11665400.0 77845.0 51043.0 75731.0 57171.0 62019.0 50910.0 43720.0 43354.0 57618.0 58327.0 True False 76734.9160249752 50924.81306957259 69504.68951011368 61375.5460568652 58371.16435404539 48732.69797700641 45983.60767639706 45368.385111558244 51128.454095561814 68408.7442341579 1.1217120981247288 0.7444196445890141 1.0160205436925496 0.8971886086197022 0.8532705139893426 0.7123752748654195 0.6721890335977911 0.6631957013604245 0.7473964720146452 1.0 16.06189312654599 -6.512463909508468 2.4623462432421546 0.732681467249041 0.9366678482977886 0.31164387403237503 0.12657162700647462 0.31946917917884265 3.8867876204400154 0.04222677751589676 0.0455694076122359 3.072812709781099e-07 6.512463909508468 0.20398638104874756 RAS(ph)FAEK ddPTM_PC-9_AZD4547_30min_R2 2 RASFAEK 7 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 RAS(1)FAEK;RAS(1)FAEK 72.243 0.018037 84456000.0 203791.0 195081.0 268260.0 378380.0 338950.0 330620.0 233650.0 306670.0 267970.0 284450.0 True False 268592.29888387234 258137.1182331226 264702.69712202984 291150.33691272495 291892.64320287993 309946.2791346054 254444.3973599738 259281.1980755376 282134.3471284027 274491.492079841 0.978508648296273 0.9404193779457419 0.9643384394771556 1.060689840354099 1.0633941365220074 1.1291653405579933 0.9269664259246473 0.9445873754080539 1.0278436864860592 1.0 18.066401907731247 -5.653283374200415 7.927624247100358 1.02166242493489 0.9578956867433415 0.19996853463298792 0.055657174537783925 0.4207268296666171 28.07834621413929 0.016747179525636483 0.02907549853913193 2.221859669226154e-06 5.653283374200415 -0.06376673819154854 RAS(ph)FAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RASFAEK 7 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 RAS(1)FAEK;RAS(1)FAEK 65.278 0.026241000000000004 571960000.0 197117.0 189338.0 198215.0 242040.0 266670.0 206825.0 259200.0 216130.0 225700.0 195472.0 True False 230485.0148617867 208134.22534874993 202941.19733457346 228479.28350426754 214417.927806612 195978.73290539611 234646.69955450812 210456.81650866364 229000.43551754992 230909.5262444999 0.9981615683440289 0.9013669930982656 0.8788775440978905 0.9894753465577723 0.9285798264536489 0.8487251959361906 1.0161845783099095 0.9114254397881368 0.9917322998405509 1.0 17.816968167610334 -8.297302537156584 1.0762598116887494 1.001643818669427 0.9289397543193478 0.16780154418236148 0.05160539471078208 0.8677185840800299 2.081635780806666 0.0475332711200712 0.015893016485963033 5.043098640700216e-09 8.297302537156584 -0.07270406435007915 RAS(ph)FAEK ddPTM_PC-9_Lapatinib_30min_R1 3 RASFAEK 7 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 RAS(1)FAEK;RAS(1)FAEK;RAS(1)FAEK 68.626 0.022298 113388000.0 575739.0 491088.0 552811.0 447864.0 522196.0 571384.0 527728.0 503547.0 572948.0 385377.0 True False 567528.856282399 489950.9159083565 507361.0134921701 480801.4125905067 491481.4579568373 546947.238281159 555051.1736470642 526943.6319087015 508416.5628300875 451988.90096742613 1.255625647151233 1.0839888210964415 1.1225076819502133 1.0637460600501716 1.0873750592213267 1.2100899759053514 1.2280194767151276 1.1658331228506809 1.1248430254412995 1.0 18.785927820714768 -8.657861394562882 5.393853811606277 1.000001143398104 1.1481339186749706 0.35288081086688616 0.061378938697249585 2.5680401480279715 102.09879843127179 0.06316920118637435 0.016401311865696096 2.1985614334966573e-09 8.657861394562882 0.14813277527686664 RAS(ph)FAK ddPTM_PC-9_Lapatinib_30min_R1 1 RASFAK 6 1 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;F6UYG0;K7ENT7;Q96J92-2;Q96J92-3;Q96J92;F8W9F9;H0Y7T5;Q9Y3S1-2;Q9Y3S1-4;Q9Y3S1;A6PVV2;Q9Y3S1-3 F5GWT4;F8W9F9 WNK1;WNK4;WNK2 Serine/threonine-protein kinase WNK1;Serine/threonine-protein kinase WNK4;Serine/threonine-protein kinase WNK2 1 RAS(1)FAK 60.118 0.043371 7621500.0 61045.0 59689.0 42703.0 42702.0 58309.0 41912.0 62781.0 62540.0 60218.0 67954.0 True False 60174.48710571801 59550.79378778123 39192.1241783469 45842.447529696095 54879.37925990471 40119.52146164394 66031.49299020776 65445.836713494784 53435.61471634806 79699.75835698674 0.7550146744007401 0.747189138529688 0.49174708915426957 0.5751892913446631 0.688576482429119 0.5033832258555013 0.8285030513448127 0.8211547696337224 0.6704614395065317 1.0 16.282287729640913 -7.284776044713216 24.821531815859352 0.8151260788493382 0.6266364396606358 0.4375713047315558 0.11234113992442314 778.4436823221623 827970.8447420371 0.04723194782735947 0.0318658187176433 5.190676407042203e-08 7.284776044713216 -0.18848963918870243 RAS(ph)GLSTEGATGPSADTSGSELDGR ddPTM_PC-9_AZD4547_30min_R2 1 RASGLSTEGATGPSADTSGSELDGR 25 1 Q7Z628 Q7Z628 NET1 Neuroepithelial cell-transforming gene 1 protein 1 RAS(0.776)GLS(0.211)T(0.013)EGATGPSADTSGSELDGR 71.678 0.00017073 6344600.0 2057.5 0.0 2052.6 2160.1 1971.7 2280.8 0.0 3029.1 1262.7 2313.3 True False 2711.742201341409 0.0 2025.3811828549858 1662.1223182123188 1697.9634890193815 2138.181215444345 0.0 2561.022196793331 1329.4437441468588 2232.31207111372 1.2147684172081268 0.0 0.907301989297807 0.7445743539715177 0.7606299813503462 0.9578325732824569 0.0 1.1472509735234353 0.5955456503371358 1.0 11.12432301074348 -9.194025821023667 0.9405519112360402 1.0002735052124232 0.6823106878483176 0.0435542539912086 0.39729282628528145 9.6668801655285 10.762775409973086 0.3963043817343599 0.11747299367062508 6.396968011120364e-10 9.194025821023667 -0.3179628173641056 RAS(ph)GLSTEGATGPSADTSGSELDGR ddPTM_PC-9_Lapatinib_30min_R1 2 RASGLSTEGATGPSADTSGSELDGR 25 1 Q7Z628 Q7Z628 NET1 Neuroepithelial cell-transforming gene 1 protein 1 RAS(0.52)GLS(0.24)T(0.24)EGATGPSADTSGSELDGR;RAS(0.415)GLS(0.415)T(0.17)EGATGPSADTSGSELDGR 70.461 0.00021381 10090000.0 2378.0 2604.9 6327.4 1896.5 3468.3 6045.9 6150.9 3353.2 9197.2 2957.4 True False 2344.08928392821 2598.8685140945804 5807.1855964703245 2035.97493653854 3264.3014129401577 5787.3309506812575 6469.363505415156 3509.001913458438 8161.314485190417 3468.582649512203 0.6758060916489524 0.7492595035785199 1.674224368644353 0.5869760482209831 0.9411052705920749 1.6685002306331513 1.8651317149167435 1.0116529626162778 2.352924900416649 1.0 11.760130546243017 -6.757555969476031 24.816321218175524 1.5982134245117394 0.9384762040729977 0.33513013573176076 0.46014897179650044 105.93720760847125 676974.9283310762 0.14848246587481942 0.1431598700907112 1.747608025827286e-07 6.757555969476031 -0.6597372204387417 RAS(ph)GQAFELILS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 13 RASGQAFELILSPR 14 1 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 2 RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR 136.67 1.1041e-05 53902200.0 115638.09999999999 129634.9 179018.9 277198.5 221547.8 224875.0 143541.8 214158.09999999998 158212.7 172763.9 True False 152408.61037809882 171536.84627636237 176644.9924171286 213294.66849913288 190789.71216339638 210813.53070109023 156316.7421226875 181064.88650856214 166575.50032437145 166715.48844623842 0.9141838697683257 1.0289196755206023 1.0595595769981037 1.279393237467046 1.1444030422219666 1.2645107702100056 0.9376257933772946 1.0860711754861998 0.9991603172376385 1.0 17.347028616353093 -11.01200876713502 8.853120891678042 0.999997410534329 1.0865284013571284 0.036839072039336895 0.1165238777569663 6.246717108390813e-06 3.6037051485793405e-07 0.11802533007455174 0.028624488632456712 9.727275870545854e-12 11.01200876713502 0.08653099082279936 RAS(ph)GQAFELILS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 17 RASGQAFELILSPR 14 1 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 2 RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR 115.02 0.00033458 24716600.0 95656.4 107337.29999999997 126136.2 147406.19999999998 180118.90000000002 170894.2 198768.0 171587.1 177634.40000000002 143982.4 True False 111849.13921998085 117993.03777649699 129143.76538220218 139147.5085113482 144825.89453934217 161932.20730995483 179939.25608429997 167083.1204365605 180231.9670487319 170085.2693559489 0.6576062679826 0.6937287292620563 0.75928836089817 0.8181044075024794 0.8514899325952519 0.952064855017329 1.0579355682338896 0.9823491538640798 1.059656534226655 1.0 17.37589867277275 -6.242638588378728 0.7321940981243655 1.038210212256832 0.6531329841523045 0.9520848314197037 0.03074474712135288 0.14947846826771694 0.1715437358544002 0.018368602358376538 0.033605085713087374 5.719544082784176e-07 6.242638588378728 -0.3850772281045275 RAS(ph)GQAFELILS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 14 RASGQAFELILSPR 14 1 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 2 RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR 147.87 1.6654e-08 37700200.0 174486.4 166232.9 203578.5 166054.3 204003.5 268154.0 262597.0 235445.60000000003 274916.50000000006 222175.59999999998 True False 171998.19193911276 165847.99793336875 186841.06156573535 178266.487162906 192004.41521631283 256685.6785175047 276192.98776301113 246385.26211242087 243952.5087709143 260578.3564296214 0.6600632312513917 0.6364611405405114 0.7170244840200246 0.6841185492358929 0.7368394591442998 0.9850613920302009 1.059922978820411 0.9455323361783737 0.936196359949037 1.0 17.99135773344497 -6.702642893357295 3.801121647495031 0.9886698022039258 0.6784336269508358 0.9422515655783663 0.03716010469628092 0.053494633654080144 1.5622641796667398 0.014137274375979678 0.013699523964131875 1.983157042989771e-07 6.702642893357295 -0.31023617525309 RAS(ph)GQAFELILSPR ddPTM_PC-9_AZD4547_30min_R2 9 RASGQAFELILSPR 14 1 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR 206.45 3.818399999999999e-11 498052000.0 98214.48999999999 96924.02 141163.7 221255.80000000002 201031.84 200824.9 139813.40000000002 189698.69999999998 131646.96000000002 176877.19999999998 True False 129444.65483170052 128252.81401248492 139291.77710327698 170248.69367803377 173122.039078149 188267.2872560022 152256.52174555513 160385.12475746602 138605.54954300457 170684.78306522928 0.7583842713279934 0.751401570247018 0.8160761293526965 0.9974450599557616 1.0142792811939674 1.1030115507370892 0.8920333670715593 0.9396568450754798 0.812055691514309 1.0 17.380974919006917 -5.635851647005265 4.076947290199717 0.9675031546030292 0.7604020095341504 0.5921191736677776 0.07326679929558347 0.15889028167118605 4.779747024503818 0.021815566191675427 0.03952587839288581 2.31285471576875e-06 5.635851647005265 -0.20710114506887878 RAS(ph)GQAFELILSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 9 RASGQAFELILSPR 14 1 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR 162.82 8.451000000000001e-06 283888300.0 75731.5 68921.6 93154.80000000002 114575.09999999999 132650.3 131765.8 142398.1 138889.80000000002 138269.5 116086.29999999999 True False 88551.34718469455 75763.68096101379 95375.96372354635 108155.82860448599 106658.42595314595 124855.7694875662 128909.12109503386 135244.08991590765 140291.42985730543 137131.82725135487 0.645738840935773 0.5524879415640196 0.6955056724266323 0.7886996824321642 0.7777802432228013 0.9104798790343006 0.9400379450844095 0.9862341414587359 1.0230406220735262 1.0 17.065203922933875 -6.293893633898637 0.5988592350539843 1.0211964166717082 0.5579274551165428 0.9431155209464578 0.03714901411743793 0.2032480170072057 0.15274898243522325 0.02656632929848553 0.05070610348213655 5.082839146884959e-07 6.293893633898637 -0.4632689615551654 RAS(ph)GQAFELILSPR ddPTM_PC-9_Lapatinib_30min_R1 6 RASGQAFELILSPR 14 1 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR 118.52 5.2477e-05 280840900.0 92232.0 68599.3 82789.23999999999 68937.14 88286.1 97845.7 97646.40000000001 95771.8 121171.90000000001 88354.67 True False 90916.7547667229 68440.46253557852 75982.62826290826 74007.00724315752 83093.28517515097 93661.06750046695 102702.0528044953 100221.70746014503 107524.2446253255 103626.6569843027 0.8773491050714384 0.6604522863836653 0.7332343865383794 0.7141695910770147 0.8018524151342439 0.903831796046983 0.9910775450379774 0.9671421464008682 1.0376118245483226 1.0 16.661035644953245 -6.856702590585035 1.7246758120315868 1.0001137267791809 0.7384185861375429 0.8207887733652186 0.05385050431703184 0.13802505945878216 0.8453090119874316 0.022936292993805785 0.01945016725620063 1.3909048113436934e-07 6.856702590585035 -0.261695140641638 RAS(ph)HTLLPSHR ddPTM_PC-9_Lapatinib_30min_R1 1 RASHTLLPSHR 11 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 RAS(0.988)HT(0.012)LLPSHR 66.708 0.01523 3140900.0 6191.2 4683.0 7220.7 5796.2 5799.3 6231.4 7033.2 6398.1 9000.7 7817.4 True False 6102.912352672974 4672.156801222661 6627.041918708043 6222.4718835563845 5458.196575862481 5964.897548102881 7397.344682288098 6695.379083412394 7986.94638442715 9168.627173969258 0.6656298960437407 0.5095808470091824 0.7227954406874504 0.6786699650327878 0.5953123049172402 0.6505769549707378 0.8068105008446601 0.7302488100313765 0.871116933089282 1.0 13.162490018746835 -8.22069071317192 0.5656695707718238 1.0056485866370488 0.6183279767765241 0.7777612020540475 0.06291283259408871 0.3670940765292631 0.2837932520928894 0.06473780811267621 0.0324412086988357 6.016020214002242e-09 8.22069071317192 -0.38732060986052474 RAS(ph)ISEPSDTDPEPR ddPTM_PC-9_AZD4547_30min_R2 2 RASISEPSDTDPEPR 15 1 Q8N1F8 Q8N1F8 STK11IP Serine/threonine-protein kinase 11-interacting protein 1 RAS(0.991)IS(0.009)EPSDTDPEPR;RAS(1)ISEPSDTDPEPR 163.34 0.00049223 79479000.0 30283.4 31890.1 39849.0 64459.0 42263.0 39633.0 32862.7 50107.0 37043.0 35816.0 True False 39912.89126614941 42197.951180105214 39320.57622312592 49598.97343162252 36395.51196248216 37154.74224469735 35787.41663651448 42364.11449431301 39001.017355216674 34562.09274154194 1.1548169714322902 1.220931599705632 1.1376792637288573 1.4350685822912275 1.0530471124723457 1.075014251091317 1.0354528270071954 1.2257392748499116 1.1284333285854349 1.0 15.076902955165309 RAS(ph)ISEPSDTDPEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RASISEPSDTDPEPR 15 1 Q8N1F8 Q8N1F8 STK11IP Serine/threonine-protein kinase 11-interacting protein 1 RAS(0.996)IS(0.002)EPS(0.001)DT(0.001)DPEPR;RAS(0.921)IS(0.079)EPSDTDPEPR 137.52 6.2383e-05 56393000.0 27962.0 28726.2 31163.0 37493.0 43726.0 26004.0 33727.0 32489.0 30845.0 31754.0 True False 32695.41432532598 31577.94729115801 31906.044106335637 35392.388763946066 35158.204189717406 24640.304462574277 30532.134397665497 31636.19817494094 31296.049771993057 37510.74883547429 0.8716278757518592 0.8418372938823986 0.8505840351595907 0.9435265853843774 0.9372834529090484 0.6568864986046798 0.813956941557801 0.8433902056634569 0.8343221808037079 1.0 15.195016443680306 -3.7348438735867697 3.4010201941213967 0.8504767829257722 11.106747969773137 0.0 0.08817975516701365 15540.760571193588 378.2141541117199 0.02327811900476676 1238639.4562517519 0.00018414338675677345 3.7348438735867697 10.256271186847364 RAS(ph)ISEPSDTDPEPR ddPTM_PC-9_Lapatinib_30min_R1 3 RASISEPSDTDPEPR 15 1 Q8N1F8 Q8N1F8 STK11IP Serine/threonine-protein kinase 11-interacting protein 1 RAS(0.961)IS(0.039)EPSDTDPEPR;RAS(0.984)IS(0.003)EPS(0.013)DT(0.001)DPEPR;RAS(0.993)IS(0.007)EPSDTDPEPR 133.9 1.0359e-05 66870800.0 50213.8 41433.3 45534.1 41168.6 36029.9 34625.2 39349.3 28934.6 41252.4 34013.1 True False 49497.74200391684 41337.36373950435 41790.462064708954 44196.27617842369 33910.69211950886 33144.360911283475 41386.614216396396 30279.007146950516 36606.12030496986 39892.2190153931 1.2407868808906641 1.0362262305727745 1.0475842932824415 1.1078921471219687 0.8500578046667154 0.8308477625296841 1.0374608191243173 0.7590203777650684 0.9176255723163647 1.0 15.283819755505569 -6.256132668960344 24.838129313907366 0.8906182963730951 1.0986628108477052 0.5543978588106563 0.09142425172193691 306.2148992495533 1433241.6964153084 0.026534529749415597 0.033233535581830925 5.544563109000577e-07 6.256132668960344 0.20804451447461014 RAS(ph)LPAGLVGTPPESPSEPR ddPTM_PC-9_AZD4547_30min_R2 1 RASLPAGLVGTPPESPSEPR 20 1 A0A590UJ23;K7EKN5;A0A590UJ36;A6NDB9 A0A590UJ23 PALM3 Paralemmin-3 1 RAS(0.998)LPAGLVGTPPES(0.001)PS(0.001)EPR 52.272 0.017145 4166500.0 5404.6 7219.9 5328.7 5489.2 6967.2 6441.7 5997.9 7574.3 5373.3 2671.5 True False 7123.15037733647 9553.591482160347 5258.03795628927 4223.749747294595 5999.924542626072 6038.899480676882 6531.701480528086 6403.865975098787 5657.321668190636 2577.9715981413133 2.7630833413650393 3.705855987338407 2.0396027481762222 1.6384004192830783 2.3273819412719465 2.34250039256866 2.5336592091384422 2.484071577714781 2.1944856461062243 1.0 11.33202065408454 -5.27369230688609 24.86874127742061 2.143082793267769 3.2344696647013462 0.4738398739852774 0.485969157634514 533.8663279580021 1083544.5024122563 0.1233149798577535 0.2597659125205624 5.3248538600188824e-06 5.27369230688609 1.0913868714335773 RAS(ph)LSDIGFGK ddPTM_PC-9_AZD4547_30min_R2 1 RASLSDIGFGK 11 1 Q07002;Q07002-3;A0A0A0MSJ6;D6R9B0;D6RA44 Q07002 CDK18 Cyclin-dependent kinase 18 1 RAS(0.965)LS(0.035)DIGFGK 103.14 0.0013889000000000002 36015000.0 164220.0 154050.0 207530.0 284890.0 270780.0 240460.0 179590.0 277750.0 198650.0 227670.0 True False 216438.54401180425 203843.64988805956 204778.01660230683 219213.0120066234 233186.87100302693 225423.9981873674 195573.1620880706 234830.11956005014 209150.23344798747 219699.3425973545 0.985157904675544 0.9278300402639172 0.9320829738558019 0.9977863812199821 1.0613908455356245 1.0260567715967386 0.8901854679032871 1.0688703788723937 0.951983883863046 1.0 17.74517102725237 -5.779087019925661 16.585530942643928 1.001473079406762 0.9463048341503593 0.1751667827758423 0.05063586477482778 7.741638457908522 7275.72445632008 0.01416158438430012 0.02120087019306442 1.6630793844634219e-06 5.779087019925661 -0.055168245256402626 RAS(ph)LSDIGFGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RASLSDIGFGK 11 1 Q07002;Q07002-3;A0A0A0MSJ6;D6R9B0;D6RA44 Q07002 CDK18 Cyclin-dependent kinase 18 1 RAS(0.929)LS(0.071)DIGFGK;RAS(0.99)LS(0.01)DIGFGK;RAS(0.956)LS(0.044)DIGFGK 101.2 0.002897 45969000.0 571657.0 559964.0 562907.0 582080.0 700386.0 553064.0 555633.0 574286.0 480171.0 446623.0 True False 668427.23935959 615553.5252468463 576328.8377166844 549467.9447288207 563150.3910629682 524060.350226472 502999.4198054396 559211.6010063136 487192.59248071513 527592.2144342774 1.2669391645142567 1.1667221547362812 1.0923755543562483 1.041463330382917 1.0673970836867235 0.9933056930879989 0.9533867370366563 1.0599314881966952 0.9234264250906703 1.0 19.009063749640497 -1.995903606800257 0.40938750364685134 0.978894545422478 4.39155279885476 0.8582139830986646 0.03643038437327627 16.71027212904111 0.32049439714367045 0.024534839709906206 43.97210677780319 0.010094769181937847 1.995903606800257 3.412658253432282 RAS(ph)LSDIGFGK ddPTM_PC-9_Lapatinib_30min_R1 1 RASLSDIGFGK 11 1 Q07002;Q07002-3;A0A0A0MSJ6;D6R9B0;D6RA44 Q07002 CDK18 Cyclin-dependent kinase 18 1 RAS(0.997)LS(0.003)DIGFGK 130.66 9.078700000000001e-05 33899000.0 380050.0 354580.0 375820.0 309310.0 319030.0 328310.0 286730.0 289150.0 339810.0 279220.0 True False 374630.4173073667 353758.9917953309 344921.5303071531 332057.6892279115 300265.2826371128 314268.9466279897 301575.47641933494 302584.9645939727 301537.01944206445 327482.80496273626 1.143969734075031 1.08023684429961 1.0532508121957769 1.0139698457318875 0.9168886979311157 0.9596502224406862 0.9208894996903753 0.9239720681774525 0.9207720676399357 1.0 18.32105963193805 -5.635375982848944 1.054206070523732 0.9335294455798937 1.1369168789011739 0.8589925959309608 0.028252324014486973 0.21286252725985866 0.4254124806351975 0.009973091734532341 0.035493857874853124 2.3153892742819656e-06 5.635375982848944 0.20338743332128018 RAS(ph)LSDLTDLEDIEGLTVR ddPTM_PC-9_AZD4547_30min_R2 4 RASLSDLTDLEDIEGLTVR 19 1 J3KSI3;J3KSU7;K7EN88;Q8WZ73-3;Q8WZ73-2;Q8WZ73 J3KSI3 RFFL;hCG_2039718 E3 ubiquitin-protein ligase rififylin 1 RAS(0.996)LS(0.004)DLTDLEDIEGLTVR;RAS(0.988)LS(0.012)DLTDLEDIEGLTVR;RAS(0.998)LS(0.002)DLTDLEDIEGLTVR;RAS(0.993)LS(0.007)DLTDLEDIEGLTVR 203.93 1.1603e-20 15071700.0 29975.7 29557.9 42000.6 52419.2 41987.6 27181.2 42030.2 46070.5 31816.6 32701.600000000002 True False 39507.349066707015 39111.913138761905 41443.64460129546 40334.76330856682 36158.34649873214 25481.55526711498 45770.80637671375 38951.362819770635 33498.36052112375 31556.726937592382 1.2519469824876972 1.239416027400779 1.3133061829655455 1.278166883033661 1.1458205589648152 0.8074841005376806 1.4504294588989408 1.2343283540400791 1.061528357721357 1.0 14.945659956390683 -14.522869734167926 0.03695404811438462 0.019690379738528482 1.7968980994625068 0.16786701309617968 0.15761464843130085 2020.2656923301245 5.5704370847238325 231.2528539006837 75.88163872511797 3.000062247205104e-15 14.522869734167926 1.7772077197239784 RAS(ph)LSDLTDLEDIEGLTVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RASLSDLTDLEDIEGLTVR 19 1 J3KSI3;J3KSU7;K7EN88;Q8WZ73-3;Q8WZ73-2;Q8WZ73 J3KSI3 RFFL;hCG_2039718 E3 ubiquitin-protein ligase rififylin 1 RAS(0.988)LS(0.012)DLTDLEDIEGLTVR;RAS(0.931)LS(0.069)DLTDLEDIEGLTVR;RAS(0.984)LS(0.016)DLTDLEDIEGLTVR;RAS(0.774)LS(0.226)DLT(0.001)DLEDIEGLTVR 189.07 1.7729e-11 11282300.0 23513.6 21020.6 23231.7 23714.4 31994.5 22717.7 23932.5 22332.2 20420.8 18064.9 True False 27493.98806523082 23107.386247694274 23785.63183471288 22385.759051122135 25725.40739944 21526.343819774796 21665.44034370471 21746.003412921786 20719.41556764195 21339.923368330274 1.288382698976021 1.0828242374097286 1.1146071812990754 1.0490084085467684 1.2055060815081486 1.0087357601162328 1.0152538961717887 1.0190291238437228 0.9709226790566083 1.0 14.381267375002865 -1.5228787452803383 0.2584722912654663 0.9838812235663966 2.6076169170653096 0.5990770638935655 0.06087078590954825 37.798679961121465 0.5205016339238092 0.07597851613130413 26.98015888314357 0.02999999999999995 1.5228787452803383 1.623735693498913 RAS(ph)LSDLTDLEDIEGLTVR ddPTM_PC-9_Lapatinib_30min_R1 3 RASLSDLTDLEDIEGLTVR 19 1 J3KSI3;J3KSU7;K7EN88;Q8WZ73-3;Q8WZ73-2;Q8WZ73 J3KSI3 RFFL;hCG_2039718 E3 ubiquitin-protein ligase rififylin 1 RAS(0.985)LS(0.015)DLTDLEDIEGLTVR;RAS(0.792)LS(0.208)DLTDLEDIEGLTVR;RAS(0.875)LS(0.123)DLT(0.002)DLEDIEGLTVR 152.27 2.1233e-05 6984400.0 19081.6 19839.0 13646.2 9567.6 13707.8 13220.9 9531.5 9601.0 16165.599999999999 7102.099999999999 True False 18809.492884863113 19793.064014404532 12524.262111855314 10271.23322057797 12901.534154571711 12655.472926423176 10024.994432012316 10047.097510173699 14344.859896685313 8329.688522046603 2.258126799709147 2.3762069808513537 1.5035690804892312 1.2330873109351668 1.5488615355093502 1.519321267887425 1.203525726739801 1.2061792567130865 1.7221364110696402 1.0 13.024046833542181 -5.3118043242887145 4.4970054139595845 1.3673515701079415 2.3247408650541788 0.7837916836311642 0.20040010800111976 0.08189776636735632 3.6200955238454005 0.05127934945373561 0.11778754959777386 4.8774820042074255e-06 5.3118043242887145 0.9573892949462373 RAS(ph)LSEIGFGK ddPTM_PC-9_AZD4547_30min_R2 2 RASLSEIGFGK 11 1 Q00537-2;Q00537;F5H6Z0 Q00537-2 CDK17 Cyclin-dependent kinase 17 1 RAS(1)LSEIGFGK;RAS(0.994)LS(0.006)EIGFGK 137.39 4.1701000000000006e-05 41247000.0 197573.0 162149.0 212900.0 295130.0 283700.0 228350.0 177507.0 279420.0 207550.0 229600.0 True False 260397.10422630687 214560.49325348233 210076.80689361139 227092.3382130462 244313.1520184599 214071.2384017519 193304.77912337644 236242.05943283188 218520.66927827714 221561.77388480102 1.175279921534199 0.9684003223635548 0.9481635898205024 1.0249617261645538 1.1026863873435506 0.9661921126929425 0.8724644857911431 1.066258205513663 0.9862742360597588 1.0 17.757349468712178 RAS(ph)LSEIGFGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RASLSEIGFGK 11 1 Q00537-2;Q00537;F5H6Z0 Q00537-2 CDK17 Cyclin-dependent kinase 17 1 RAS(1)LSEIGFGK;RAS(0.979)LS(0.021)EIGFGK 139.64 5.1892e-05 30068000.0 278100.0 271850.0 252210.0 261570.0 313800.0 252650.0 215610.0 271710.0 205122.0 168755.0 True False 325176.83727462735 298837.47140593926 258223.64291175196 246915.08092138162 252313.14263214843 239400.58923509452 195185.8599187788 264577.90040054143 208121.5211973018 199348.94563615456 1.6311941667759302 1.4990672283332165 1.2953348816956054 1.2386074083985539 1.2656858646880553 1.2009122419540708 0.979116590237833 1.3272099310895815 1.0440061297196859 1.0 17.604936449325535 -1.522878745286962 0.3270900659146848 1.0759358939081813 6.9360695384524025 0.7792790519230405 0.09354061934782022 26.301065138273025 0.37476897998977704 0.0840270544570692 92.89092242546356 0.029999999999542393 1.522878745286962 5.860133644544221 RAS(ph)LSEIGFGK ddPTM_PC-9_Lapatinib_30min_R1 1 RASLSEIGFGK 11 1 Q00537-2;Q00537;F5H6Z0 Q00537-2 CDK17 Cyclin-dependent kinase 17 1 RAS(1)LSEIGFGK 153.0 0.00018518 15884000.0 153900.0 127680.0 148980.0 116660.0 104800.0 111740.0 108820.0 102560.0 125210.0 120230.0 True False 151705.3577781969 127384.36480463554 136731.43947943047 125239.56556635168 98635.8700447274 106961.14067866227 114454.16713965056 107325.31201368774 111107.5312802473 141011.5953035949 1.0758360505856173 0.9033609224147828 0.9696467810682565 0.888150831119339 0.6994876544185358 0.758527271806104 0.8116649336051637 0.7611098348516566 0.7879318792262098 1.0 17.105454273934555 -5.978676035566688 3.818714280435703 0.7889999563896537 0.973260050364525 0.47230630754387637 0.08407101305632869 0.17768476128066737 5.718051364695622 0.023427760858824642 0.03449402386607161 1.050325632864418e-06 5.978676035566688 0.1842600939748713 RAS(ph)LTLEEK ddPTM_PC-9_AZD4547_30min_R2 2 RASLTLEEK 9 1 A0A0U1RQQ9;Q6P3W7 A0A0U1RQQ9 SCYL2 SCY1-like protein 2 1 RAS(0.987)LT(0.013)LEEK;RAS(0.978)LT(0.022)LEEK 82.505 0.0071869 10590300.0 41948.0 46302.0 61939.0 100143.0 83013.0 71602.0 57504.0 84063.0 61632.0 71372.0 True False 55286.59142739705 61268.216015040154 61117.64838977635 77056.57854392668 71488.07785868332 67124.71562094266 62621.74459999115 71072.99492556804 64889.74169577822 68873.28800394593 0.802729084521557 0.8895787872292367 0.8873926330666072 1.1188166091259053 1.0379652246976736 0.9746117481293606 0.9092312333978216 1.0319384624340293 0.9421612293587686 1.0 16.07165693234157 -5.546161411023508 24.295341776511133 1.0001588859719786 0.8567368528936706 0.5692762506047413 0.057270057935959205 121.32142754305008 126597.57202617251 0.016279124821404364 0.028198793067436834 2.8434041240227554e-06 5.546161411023508 -0.14342203307830792 RAS(ph)LTLEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RASLTLEEK 9 1 A0A0U1RQQ9;Q6P3W7 A0A0U1RQQ9 SCYL2 SCY1-like protein 2 1 RAS(0.992)LT(0.008)LEEK;RAS(0.974)LT(0.026)LEEK 100.04 0.0018100999999999998 13576300.0 60767.0 59195.0 66470.0 71357.0 87075.0 86294.0 82924.0 85043.0 70299.0 69442.0 True False 71053.65289704174 65071.48839387379 68054.89688887876 67359.09863251532 70013.27882311771 81768.59072809505 75068.83840222994 82810.71136050666 71326.98988235841 82031.28489743054 0.8661774954017251 0.7932520924819991 0.8296212472347906 0.8211391387656444 0.8534948454197715 0.9967976343456774 0.9151244978802144 1.0095015756982313 0.8695096019956721 1.0 16.323886605848784 -6.641581792162475 5.299615620012259 0.9556602699841508 0.8267285948828705 0.682423909936788 0.04298691987048497 0.11574992857387706 4.911656209043228 0.013314312709488916 0.013263003093510499 2.282539005832764e-07 6.641581792162475 -0.12893167510128023 RAS(ph)LTLEEK ddPTM_PC-9_Lapatinib_30min_R1 3 RASLTLEEK 9 1 A0A0U1RQQ9;Q6P3W7 A0A0U1RQQ9 SCYL2 SCY1-like protein 2 1 RAS(0.748)LT(0.252)LEEK;RAS(0.965)LT(0.035)LEEK;RAS(0.973)LT(0.027)LEEK 67.252 0.021203 18675500.0 113121.0 90912.0 109768.0 97627.0 113251.0 116606.0 104370.0 101652.0 103746.0 95179.0 True False 111507.87379614911 90701.4988496165 100743.29875673345 104806.81525412491 106589.79884003267 111619.03320186216 109773.76791366788 106375.12301887086 92061.03298618752 111630.5633319542 0.9989009323957253 0.8125149255038583 0.9024705757074302 0.9388720447684421 0.9548442259766093 0.9998967117091602 0.9833666035280607 0.9529211341749184 0.8246937956626355 1.0 16.768372551162187 -5.821521742741469 3.617800527481593 0.9534955833257331 0.8947353238940401 0.09905461495434265 0.06280630652872496 0.4581646757719754 12.0752609306716 0.018012345243072225 0.02914833700695559 1.5082670979934358e-06 5.821521742741469 -0.05876025943169305 RAS(ph)MQPIQIAEGTGITTR ddPTM_PC-9_AZD4547_30min_R2 4 RASMQPIQIAEGTGITTR 18 1 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 RAS(1)MQPIQIAEGTGITTR;RAS(1)MQPIQIAEGTGITTR;RAS(1)MQPIQIAEGTGITTR;RAS(1)MQPIQIAEGTGITTR 111.6 7.3768e-05 18363300.0 29209.800000000003 30173.399999999998 29031.6 56785.0 57396.0 49488.8 36655.9 54072.0 38782.100000000006 35225.2 True False 38497.908798416676 39926.361477003404 28646.622015089546 43694.09556950442 49427.556127076336 46394.257512663164 39918.2040881124 45716.41485094881 40832.042630773656 33991.976469716436 1.132558703455052 1.174581934433084 0.8427465828770185 1.285423800185071 1.4540947970798788 1.3648590735521355 1.1743419545984817 1.3449178188175588 1.2012259030348253 1.0 15.052906629636093 -5.845942744371046 24.99997587484052 1.2838693806002375 1.0624186175981727 0.30338573222712906 0.14297885169127791 26.998503883916424 7983.608296745141 0.03945157814170867 0.05851617019684926 1.4257955523342114e-06 5.845942744371046 -0.2214507630020648 RAS(ph)MQPIQIAEGTGITTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RASMQPIQIAEGTGITTR 18 1 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 RAS(1)MQPIQIAEGTGITTR 104.26 0.00013778 4966200.0 5334.5 7106.5 5731.8 8893.7 7693.1 7066.7 6457.3 6751.3 5898.1 6088.8 True False 6237.525488822375 7811.986354777669 5868.46784997255 8395.414822764433 6185.692280380432 6696.109811785634 5845.617797196471 6574.085528593642 5984.348554391063 7192.651241085719 0.8672081100210318 1.0861066514881461 0.8158977341276892 1.1672211735789872 0.8600016979895596 0.9309654517288769 0.8127208731886302 0.9140003189701846 0.8320087202626183 1.0 12.81230793673653 RAS(ph)MQPIQIAEGTGITTR ddPTM_PC-9_Lapatinib_30min_R1 2 RASMQPIQIAEGTGITTR 18 1 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 RAS(1)MQPIQIAEGTGITTR;RAS(1)MQPIQIAEGTGITTR 106.75 0.0005690000000000001 5524100.0 21078.0 19727.6 19784.4 15814.3 21232.5 19871.9 16641.2 15292.900000000001 21857.3 15880.900000000001 True False 20777.42385476821 19681.92195426012 18157.803001992535 16977.336376958294 19983.646094701104 19022.025160661437 17502.799909983038 16003.46396347625 19395.50070642722 18625.892405030896 1.1155129323712931 1.0566968565191532 0.9748688871996314 0.9114911655117623 1.0728960341950367 1.0212678537498447 0.9397026209200849 0.8592052190290586 1.0413192712950738 1.0 14.18502192928368 -5.065380156370267 2.7211874408430514 0.9736768114501487 1.1130743583333873 0.36304443249495044 0.059697600489594 0.328511107188729 4.430261347518464 0.01651470019732877 0.07618543720375939 8.602404176157124e-06 5.065380156370267 0.13939754688323858 RAS(ph)PGLSMPSSSPPIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RASPGLSMPSSSPPIK 16 1 P57682;P57682-2 P57682 KLF3 Krueppel-like factor 3 1 RAS(0.999)PGLS(0.001)MPSSSPPIK 70.555 0.022926 0.0 17673.0 17597.0 17116.0 18319.0 23204.0 16614.0 18552.0 18628.0 20223.0 14732.0 True False 20664.6898423391 19343.91386547845 17524.11035279147 17292.64582099933 18657.34277130774 15742.732592724538 16794.620255151374 18139.034737997485 20518.723116842793 17402.794981552168 1.1874351139713306 1.1115406396492038 1.0069710280083115 0.9936706051717783 1.0720888679712341 0.9046094382777377 0.9650530430861544 1.0423058340471039 1.1790475690022013 1.0 14.087031408738536 -5.023945248044722 2.6411907577306684 1.016633649689697 1.188675919610234 0.3849971720273463 0.06819387378290509 0.33523602316094164 4.18986713032929 0.01886944388455039 0.10023582775197824 9.4635646198508e-06 5.023945248044722 0.17204226992053706 RAS(ph)PNLFSEAQYQEAPVEK ddPTM_PC-9_AZD4547_30min_R2 2 RASPNLFSEAQYQEAPVEK 19 1 Q9HC77;F6VUX8;Q9HC77-2 Q9HC77 CENPJ Centromere protein J 1 RAS(1)PNLFSEAQYQEAPVEK;RAS(0.889)PNLFS(0.11)EAQY(0.001)QEAPVEK 95.51 0.00032398 14096000.0 61504.0 63158.0 94358.0 113498.0 95919.0 88465.0 77088.0 108621.0 82093.0 86685.0 True False 81060.99263732792 83572.5883779945 93106.75126757809 87332.78962661998 82602.30253245935 82933.26956518934 83948.68266075615 91836.12031226706 86432.26838381878 83650.18453486051 0.9690473857059625 0.9990723731537774 1.1130489643902295 1.0440238728968347 0.9874730461357862 0.9914296068364034 1.0035684096521178 1.0978591478658977 1.0332585500489704 1.0 16.352081102445887 RAS(ph)PNLFSEAQYQEAPVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RASPNLFSEAQYQEAPVEK 19 1 Q9HC77;F6VUX8;Q9HC77-2 Q9HC77 CENPJ Centromere protein J 1 RAS(0.953)PNLFS(0.047)EAQYQEAPVEK;RAS(0.957)PNLFS(0.031)EAQY(0.012)QEAPVEK 85.881 0.00058146 10843900.0 54170.0 49791.0 70870.0 78087.0 86247.0 74406.0 68394.0 74438.0 66336.0 63074.0 True False 63339.911093731054 54733.92142274467 72559.80957597154 73712.03855146957 69347.51947926998 70504.01837572297 61915.225190320256 72484.08137358053 67306.03850461765 74508.81690649063 0.8500995415512144 0.7345965711874923 0.9738419235274516 0.9893062541038462 0.9307290379647535 0.9462506761341584 0.8309785037658636 0.9728255578738935 0.9033298514065451 1.0 16.185123534716617 -5.267057259406982 24.99675741373242 0.9397098393911515 0.7923480536251251 0.5626359665444404 0.05319424568204146 296.14070261432164 1317682.9712178472 0.01368583773764236 0.029849598837036074 5.406830320771404e-06 5.267057259406982 -0.14736178576602643 RAS(ph)PNLFSEAQYQEAPVEK ddPTM_PC-9_Lapatinib_30min_R1 2 RASPNLFSEAQYQEAPVEK 19 1 Q9HC77;F6VUX8;Q9HC77-2 Q9HC77 CENPJ Centromere protein J 1 RAS(0.877)PNLFS(0.122)EAQYQEAPVEK;RAS(0.935)PNLFS(0.065)EAQYQEAPVEK 72.399 0.0025809 14597200.0 76785.0 74957.0 88255.0 80287.0 85329.0 74498.0 67429.0 66709.0 84911.0 63752.0 True False 75690.03181935573 74783.44167184451 80999.01457415195 86191.57380958078 80310.11598326858 71311.89420331996 70920.14368736907 69808.54367317744 75347.42902753047 74771.4482557998 1.0122852182883149 1.0001604010130134 1.0832880258925452 1.152733774992718 1.0740746348595591 0.9537316163698689 0.9484923101227748 0.9336256726545697 1.0077032180754368 1.0 16.19019985656987 -6.760643912618892 24.994093571847195 0.963298516585985 1.0668782539872366 0.5369626686396622 0.044310176721823843 17.604658462854587 553157.51527326 0.016720657501119448 0.01579776884280596 1.735226163873565e-07 6.760643912618892 0.10357973740125159 RAS(ph)PNSDDTVLSPQELQK ddPTM_PC-9_AZD4547_30min_R2 1 RASPNSDDTVLSPQELQK 18 1 Q9UH62 Q9UH62 ARMCX3 Armadillo repeat-containing X-linked protein 3 1 RAS(0.635)PNS(0.144)DDT(0.211)VLS(0.009)PQELQK 77.221 0.002306 3744500.0 11217.0 13355.0 17819.0 21581.0 18881.0 18634.0 11445.0 14567.0 16994.0 18615.0 True False 14783.772671906005 17671.742578740897 17582.70841727222 16605.83387312627 16259.699059783403 17468.813034281804 12463.58282809715 12316.004866359135 17892.268146061382 17963.29451596502 0.8229989581681028 0.9837695731723931 0.9788131237087635 0.9244314208826062 0.9051624157991992 0.9724726730253328 0.6938361344028536 0.6856206056975345 0.9960460276459582 1.0 14.13276434800064 -7.228757723909425 24.94738132540977 0.8176773294668502 0.9343236882859113 0.11714293540150433 0.10819129822211317 988.3806908839526 754476.485756526 0.04050839263923877 0.031375438546399834 5.90530422377373e-08 7.228757723909425 0.11664635881906105 RAS(ph)PPDPSPSPSAASASER ddPTM_PC-9_AZD4547_30min_R2 2 RASPPDPSPSPSAASASER 19 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 RAS(1)PPDPSPSPSAASASER;RAS(0.993)PPDPS(0.007)PSPSAASASER 62.707 0.0067101 25254000.0 44813.0 43241.0 68198.0 78966.0 70437.0 56067.0 45577.0 63187.0 50352.0 59930.0 True False 59062.60183169502 57217.80762615764 67293.64996021835 60761.60871253832 60658.0383811219 52561.12162676171 49633.2647056517 53422.90104281149 53013.50392435467 57831.86894127233 1.0212812228439736 0.9893819562404552 1.1636084254609576 1.050659607322065 1.0488687205097853 0.9088608511016131 0.8582338010907753 0.9237623134237958 0.9166832214637458 1.0 15.819577105719558 -6.749112251863301 6.926032596627589 0.9125247185620853 1.0574292381570245 0.6104579825916678 0.05297332428591697 0.09660436680912911 21.42969864323843 0.018235998553520347 0.017480110982546825 1.781918136489984e-07 6.749112251863301 0.14490451959493922 RAS(ph)PPDPSPSPSAASASER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RASPPDPSPSPSAASASER 19 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 RAS(0.992)PPDPS(0.007)PSPSAASASER;RAS(1)PPDPSPSPSAASASER;RAS(1)PPDPSPSPSAASASER 114.39 3.6617e-05 44878000.0 74767.0 76662.0 80997.0 87965.0 97253.0 79181.0 85053.0 83238.0 82523.0 71080.0 True False 87423.57638443788 84272.49671849217 82928.27566283324 83036.60623637769 78196.9727865018 75028.608969816 76996.16410960487 81053.09069795121 83729.74275682223 83966.24133102976 1.041175298531917 1.0036473633046765 0.987638297823712 0.9889284660130604 0.9312906180737197 0.8935568364197952 0.9169895292329932 0.9653056920626744 0.9971834088264694 1.0 16.35752178775484 -5.592165752332119 1.3219211762148262 0.9462185406709889 1.0286890807210682 0.40817921459696604 0.03319093999923989 0.5103871551015048 1.6768879396267682 0.011870259852144915 0.03794129633249594 2.557609566283367e-06 5.592165752332119 0.08247054005007937 RAS(ph)PPDPSPSPSAASASER ddPTM_PC-9_Lapatinib_30min_R1 6 RASPPDPSPSPSAASASER 19 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 RAS(1)PPDPSPSPSAASASER;RAS(0.956)PPDPS(0.005)PS(0.005)PS(0.003)AAS(0.03)AS(0.002)ER;RAS(0.964)PPDPS(0.036)PSPSAASASER;RAS(0.999)PPDPS(0.001)PSPSAASASER;RAS(1)PPDPSPSPSAASASER;RAS(1)PPDPSPSPSAASASER 102.58 0.00049187 63338800.0 124501.0 117968.7 135078.0 109369.0 120817.0 113113.0 108424.0 113531.0 126714.0 96003.0 True False 122725.59290931255 117695.55072312534 123972.40825615854 117412.36110428844 113710.7815953612 108275.42066928152 114037.66419729347 118806.06472529205 112442.13496242542 112596.99063404357 1.089954466973175 1.0452814951835865 1.1010277233703938 1.042766422469456 1.0098918359633395 0.9616191343975811 1.012794956198539 1.055144227712345 0.998624690848786 1.0 16.78080874363684 -6.057184359126293 3.480894784678402 1.0074719566122559 1.0754260557390376 0.6210420239969994 0.02530664125525528 0.17521791553698113 4.22575913549072 0.008024220666947331 0.011185542143079385 8.766286110436039e-07 6.057184359126293 0.06795409912678174 RAS(ph)PSKPASAPASR ddPTM_PC-9_AZD4547_30min_R2 1 RASPSKPASAPASR 14 2 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 RAS(0.997)PS(0.003)KPASAPASR 133.04 0.00014958 4134200.0 14765.0 13888.0 17188.0 22935.0 23094.0 20678.0 18569.0 21168.0 16726.0 19790.0 True False 19459.962868921462 18377.024405357803 16960.0758895603 17647.690092217723 19887.796731456914 19385.00139116019 20221.605027080474 17896.971992248942 17610.102213194223 19097.1581236072 1.018997839519681 0.9622910532767074 0.8880942274125531 0.924100328331172 1.041400851515826 1.0150725707819932 1.058880326391772 0.9371536789091863 0.9221320836960167 1.0 14.22107034419664 -4.753660991364334 24.157135162093855 0.9722524171119886 1.018997968116753 0.06566393546982818 0.05304132178603906 655.0331029845713 2034059.0070339115 0.014579500047713728 0.14983190581279932 1.763351975224918e-05 4.753660991364334 0.046745551004764296 RAS(ph)PSPPPKR ddPTM_PC-9_AZD4547_30min_R2 1 RASPSPPPKR 10 2 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 RAS(0.991)PS(0.009)PPPKR 49.934 0.037916000000000005 2550400.0 10735.0 5723.8 14404.0 29077.0 19601.0 15530.0 8689.5 18089.0 10998.0 13827.0 True False 14148.506698128804 7573.906414990425 14212.993548593584 22373.746885171775 16879.739487888048 14558.906644971357 9462.848666207972 15293.760693867685 11579.331827138003 13342.920938611245 1.0603755177163934 0.5676348117355128 1.0652085562063518 1.6768252609837073 1.2650707866402842 1.0911333966494052 0.7092036825928223 1.1462078479091615 0.8678258591512872 1.0 13.70378690531957 -7.025651016536266 23.976660040807875 0.936875474250103 1.1285609109368175 0.1051465532725574 0.27330141668859886 1255.9428068953878 1173957.8118819077 0.11558427801784436 0.08994975993182007 9.426467693865597e-08 7.025651016536266 0.19168543668671456 RAS(ph)PSPPPKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RASPSPPPKR 10 2 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 RAS(0.997)PS(0.003)PPPKR;RAS(0.995)PS(0.005)PPPKR 63.473 0.017585 2272900.0 11153.4 10398.5 12179.599999999999 12006.8 14665.1 15036.3 11736.6 12821.2 14046.6 10429.1 True False 13041.450330308653 11430.794358707604 12470.007855390219 11334.09792257081 11791.578929301208 14247.769958106659 10624.824282374386 12484.657085184299 14252.004951443592 12319.813273289832 1.0585753242367217 0.9278382801052936 1.0121913034531147 0.9199894244455703 0.9571231858575429 1.156492362509809 0.8624176395116073 1.0133803823351657 1.1568361171790549 1.0 13.58869276936958 RAS(ph)QEANLLTLAQK ddPTM_PC-9_AZD4547_30min_R2 2 RASQEANLLTLAQK 14 1 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2;H7C1L3 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 RAS(1)QEANLLTLAQK;RAS(1)QEANLLTLAQK 157.42 5.8200000000000005e-05 131435000.0 354414.0 376205.0 465233.0 559820.0 493680.0 486260.0 404596.0 481800.0 419998.0 425773.0 True False 467110.2797308464 497805.90916025575 459063.70644215797 430762.1481327807 425141.0535370941 455854.0853305712 440604.260193692 407348.88066258206 442198.2368370894 410866.816865215 1.13688976708986 1.211599206181601 1.1173053836390832 1.0484228232870223 1.0347417607992464 1.1094935551344713 1.0723773303362982 0.9914377699579788 1.0762568761598303 1.0 18.64831129222116 -5.57308198183413 3.4174256826118974 1.0503451799240626 1.1738891853533586 0.6544958600118881 0.037257620643312485 0.138001985459496 3.296187931642417 0.010310036958755727 0.020237477108927208 2.672501872467018e-06 5.57308198183413 0.123544005429296 RAS(ph)QEANLLTLAQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RASQEANLLTLAQK 14 1 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2;H7C1L3 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 RAS(0.998)QEANLLT(0.002)LAQK;RAS(1)QEANLLTLAQK;RAS(1)QEANLLTLAQK 178.01 1.2250999999999998e-05 47525000.0 111649.0 135705.0 128792.0 134603.0 161202.0 124433.0 138837.0 117708.0 121602.0 102704.0 True False 130548.97053173275 149176.8955568988 131862.88972638024 127061.63029881367 129615.62529823974 117907.51442822284 125685.35426716553 114618.28972193516 123380.19920161784 121323.42219558341 1.0760409504545378 1.2295803469540554 1.08687083944769 1.0472967873753165 1.0683479162769463 0.9718446141269091 1.0359529264229814 0.9447334047102709 1.0169528436373871 1.0 16.888498572491457 -5.957795073155493 1.0482241813669009 0.993425249249703 1.1559579758202452 0.6013411579633503 0.047062949855891205 0.348737583137643 0.7729363634100412 0.01816898526410641 0.0400731713603049 1.102059206179324e-06 5.957795073155493 0.16253272657054219 RAS(ph)QEANLLTLAQK ddPTM_PC-9_Lapatinib_30min_R1 4 RASQEANLLTLAQK 14 1 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2;H7C1L3 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 RAS(1)QEANLLTLAQK;RAS(1)QEANLLTLAQK;RAS(0.995)QEANLLT(0.005)LAQK;RAS(0.998)QEANLLT(0.002)LAQK 147.16 9.261399999999999e-05 94026300.0 315023.0 321205.0 368582.0 305072.0 399641.0 422379.0 444420.0 409526.0 432247.0 372093.0 True False 310530.7142518576 320461.26955727686 338278.61072766467 327508.01257035846 376134.90210443654 404314.83478353923 467429.89303623966 428554.0730081659 383562.7910973018 436408.77926724224 0.7115592742502985 0.7343144427464348 0.775141625921586 0.7504615583588052 0.8618866530045309 0.9264589852257539 1.0710826987052915 0.9820014934798863 0.8789071378016909 1.0 18.735320599191624 -6.545498659540542 1.785222904425256 0.982250379809024 0.7399020246319458 0.8411043762288849 0.04716606862152735 0.1376033389273665 0.8899206048049543 0.018952413869711953 0.02031886044313094 2.847746589792581e-07 6.545498659540542 -0.2423483551770782 RAS(ph)SASVPAVGASAEGTR ddPTM_PC-9_AZD4547_30min_R2 4 RASSASVPAVGASAEGTR 18 1 V9GYZ0;Q9BZ23-3;Q9BZ23-4;Q9BZ23;A0A2R8YFI4 V9GYZ0 PANK2 Pantothenate kinase 2, mitochondrial 1 RAS(0.613)S(0.324)AS(0.063)VPAVGASAEGTR;RAS(0.576)S(0.383)AS(0.041)VPAVGASAEGTR;RAS(0.969)S(0.03)AS(0.001)VPAVGASAEGTR;RAS(0.728)S(0.258)AS(0.015)VPAVGASAEGTR 80.453 0.0032457999999999996 21635800.0 19659.699999999997 22682.100000000002 32400.3 41031.4 34565.4 34748.2 31797.699999999997 41479.3 29198.6 32216.0 True False 25911.0756528368 30013.645252359347 31970.65085202008 31572.244658810647 29766.590852234378 32575.389560901087 34627.633699692844 35069.62728449035 30741.978385876682 31088.127645787226 0.8334717339063689 0.965437532756223 1.028387788942717 1.015572408172643 0.9574906276566344 1.0478401894144114 1.1138539475337383 1.12807138738195 0.9888655481650581 1.0 14.924076109207519 -3.664400304526015 0.7149047094739956 1.0511349419689575 4.7073929065507856e-14 0.6019961754192331 0.05004848314047731 8.904603714238492 1.0275905442384201 0.02120613128794291 10.906415930341568 0.00021657069761221712 3.664400304526015 -1.0511349419689104 RAS(ph)SASVPAVGASAEGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RASSASVPAVGASAEGTR 18 1 V9GYZ0;Q9BZ23-3;Q9BZ23-4;Q9BZ23;A0A2R8YFI4 V9GYZ0 PANK2 Pantothenate kinase 2, mitochondrial 1 RAS(0.994)S(0.006)ASVPAVGASAEGTR;RAS(0.999)S(0.001)ASVPAVGASAEGTR 180.76 1.0580000000000001e-08 14559500.0 15318.3 15643.699999999999 22623.7 12644.4 18676.1 10326.6 12654.7 11194.0 10472.099999999999 8010.1 True False 17911.38563978402 17196.703150388435 23163.134808860046 11935.975261697899 15016.652272505611 9785.05491705967 11455.955203905994 10900.16936102339 10625.234651233211 9462.267722083285 1.89292737912942 1.8173976530228928 2.4479475205294947 1.2614286143945612 1.5870035295513105 1.0341130904828508 1.2106986972234774 1.1519616313100394 1.1229057307727368 1.0 13.207970265196485 -5.831110625724555 8.701364844827742 1.2095789473734262 2.0278359883930803 0.7666381151946342 0.21657027211395738 0.13333259570367387 15.118423668392444 0.0614129572240898 0.09143423095168059 1.4753306815877887e-06 5.831110625724555 0.8182570410196541 RAS(ph)SASVPAVGASAEGTR ddPTM_PC-9_Lapatinib_30min_R1 2 RASSASVPAVGASAEGTR 18 1 V9GYZ0;Q9BZ23-3;Q9BZ23-4;Q9BZ23;A0A2R8YFI4 V9GYZ0 PANK2 Pantothenate kinase 2, mitochondrial 1 RAS(0.983)S(0.017)ASVPAVGASAEGTR;RAS(0.958)S(0.041)AS(0.001)VPAVGASAEGTR 126.25 6.4395e-05 20471200.0 25895.0 29833.0 29721.0 28619.0 32941.0 27446.0 27802.0 25629.0 28250.0 23890.0 True False 25525.73255143859 29763.923521434044 27277.45410637774 30723.736730185297 31003.475144497774 26272.198559750872 29241.45152376925 26819.816903264425 25068.187514311874 28019.354668575965 0.9110035849635751 1.0622629919030446 0.9735218540550373 1.09651835645745 1.1065021129579595 0.9376446699258013 1.0436161670976627 0.9571889581505303 0.8946739784277095 1.0 14.774136108081688 -7.863958059827794 5.492984728285654 0.9409807952690096 1.0217678897928475 0.18505570902047574 0.06500023623573313 0.31529096014425606 14.132253063033172 0.03604278339946545 0.016958872113468196 1.3678609146615453e-08 7.863958059827794 0.08078709452383792 RAS(ph)SASVPAVGASAEGTRR ddPTM_PC-9_Lapatinib_30min_R1 1 RASSASVPAVGASAEGTRR 19 2 V9GYZ0;Q9BZ23-3;Q9BZ23-4;Q9BZ23;A0A2R8YFI4 V9GYZ0 PANK2 Pantothenate kinase 2, mitochondrial 1 RAS(0.765)S(0.222)AS(0.013)VPAVGASAEGTRR 60.032 0.0065953999999999995 5982300.0 21824.0 9094.4 14879.0 8866.0 13517.0 18952.0 8954.7 8605.3 15478.0 9756.2 True False 21512.78575796857 9073.342475558273 13655.706054600943 9518.03521610898 12721.95663544448 18141.46713926979 9418.33055031639 9005.133653192146 13734.704649434305 11442.546170680649 1.880069823365974 0.7929478579520167 1.1934149839474624 0.8318109513507699 1.1118116934535145 1.585439714960806 0.8230974478782592 0.786986875024904 1.200318918933172 1.0 13.482120492775122 -4.750851200677478 24.989297731145992 1.0409389730929601 1.8800715909614936 0.5296293760573182 0.23853969672250247 371.0909426102224 875758.3867635995 0.06000415109056054 0.8436204477600079 1.7747974633419118e-05 4.750851200677478 0.8391326178685334 RAS(ph)SGLPR ddPTM_PC-9_AZD4547_30min_R2 1 RASSGLPR 8 1 Q9UJZ1;Q9UJZ1-2 Q9UJZ1 STOML2 Stomatin-like protein 2, mitochondrial 1 RAS(0.802)S(0.198)GLPR 66.19 0.022797 2218600.0 2674.4 1239.2 5599.3 2265.8 5764.3 2160.4 4626.0 2782.1 2592.2 5268.7 True False 3524.803569024285 1639.7471661232296 5525.049623482376 1743.4548162610388 4964.026444060664 2025.3098464775367 5037.705038250542 2352.190371297987 2729.2183999188132 5084.2444166674695 0.693279724607469 0.322515408729705 1.0867002391485807 0.3429132577783913 0.9763548006833228 0.39835021303028756 0.9908463530462148 0.4626430553942092 0.5367992126758755 1.0 12.311817671857467 -11.057620886686738 3.025735589999875 1.0137630758853566 0.6473979445542958 0.13438840784217387 0.26979842038190793 155228143.85321265 181850661.22498363 17596722.18494667 0.06034222133901109 8.757479176218452e-12 11.057620886686738 -0.36636513133106086 RAS(ph)SGLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RASSGLPR 8 1 Q9UJZ1;Q9UJZ1-2 Q9UJZ1 STOML2 Stomatin-like protein 2, mitochondrial 1 RAS(0.774)S(0.226)GLPR 55.806000000000004 0.04034 1532900.0 4300.8 4416.1 6178.6 4610.5 6726.8 4268.7 2339.4 5648.2 4750.4 3785.7 True False 5028.840495328013 4854.501223011845 6325.921256470987 4352.188632442676 5408.731828737843 4044.841857383125 2117.7950962107107 5499.9407347625765 4819.86561312614 4472.017442415287 1.1245127193895719 1.0855282398876294 1.4145564810351963 0.9732047534439192 1.2094612551011532 0.9044781040027765 0.47356592935534547 1.2298567269881038 1.0777832768297484 1.0 12.126710099863978 -6.765953397572019 24.821573593826304 0.922529632580889 1.16083777897581 0.2226801566897706 0.208658621974007 165.15366674750035 908135.8424350494 0.07469007764074934 0.06808780039786465 1.7141412353752975e-07 6.765953397572019 0.23830814639492093 RAS(ph)SLNFLNK ddPTM_PC-9_Lapatinib_30min_R1 1 RASSLNFLNK 10 1 Q9H0B6;Q9H0B6-2;A8MZ87 Q9H0B6 KLC2 Kinesin light chain 2 1 RAS(0.5)S(0.5)LNFLNK 79.283 0.008819 36258000.0 376790.0 252360.0 361930.0 248090.0 239550.0 276660.0 211680.0 214110.0 269120.0 217700.0 True False 371416.90550517704 251775.67592495208 332173.5124902029 266335.3662039785 225460.13997342033 264827.89672595955 222639.75464180537 224058.33224698433 238808.87164076508 255329.15493298345 1.4546592049100828 0.9860827526376138 1.3009619390209821 1.0431059714817286 0.8830176092996396 1.0372019474057683 0.8719715329815817 0.877527410866155 0.935298092783198 1.0 17.961998756700922 -1.5228787999612843 0.4055924407862438 0.9093674336193384 8.846869714335329 0.6072186265368626 0.11467389647275461 50.13507726406965 0.6590001720982637 0.07934464795636759 319.38855882970313 0.029999996222774255 1.5228787999612843 7.93750228071599 RAS(ph)SLNVLNVGGK ddPTM_PC-9_AZD4547_30min_R2 1 RASSLNVLNVGGK 13 1 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;H0YJK1 Q07866-6 KLC1 Kinesin light chain 1 1 RAS(0.651)S(0.349)LNVLNVGGK 130.01 3.9324e-05 99088000.0 161430.0 130130.0 207010.0 311200.0 275420.0 197370.0 181480.0 224090.0 166320.0 176100.0 True False 212761.3820474092 172191.97766915418 204264.91214206864 239457.64799207132 237182.68709525626 185028.42269916233 197631.36842665504 189462.03957591948 175111.33565099054 169934.79260066838 1.2520177815933167 1.013282654093032 1.2020193688179734 1.4091148982938146 1.395727640381534 1.0888201284004426 1.16298355034964 1.1149102351343576 1.0304619376120732 1.0 17.3746217358677 -7.790582263325249 1.1296074553294044 1.0096170384680005 1.2343601307677166 0.36891644835825044 0.11189381561368081 0.6391590706327591 1.4735667745862868 0.10860961459452619 0.042196615681584566 1.6196371759151996e-08 7.790582263325249 0.224743092299716 RAS(ph)SLNVLNVGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RASSLNVLNVGGK 13 1 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;H0YJK1 Q07866-6 KLC1 Kinesin light chain 1 1 RAS(0.5)S(0.5)LNVLNVGGK 86.54799999999999 0.018694 0.0 16221.0 15599.0 23105.0 27504.0 29694.0 34147.0 30278.0 29339.0 29624.0 21850.0 True False 18966.89492064631 17147.565629800447 23655.910826200452 25963.040049171115 23875.673860162555 32356.271207642065 27409.848646263115 28568.88233724006 30057.194956898118 25811.232035495163 0.7348310570593206 0.6643451039539456 0.9164967713927507 1.0058814710381585 0.925011011769184 1.2535732956546313 1.0619349207573494 1.1068391581600066 1.164500590888648 1.0 14.65571138611412 -5.586060660794779 0.9884289528307603 1.1101388494337812 0.6483753654890498 0.7533375283751209 0.08594288438767897 0.34462454821919514 0.5750211365283853 0.03184070161547545 0.12944505981849339 2.5938170411617976e-06 5.586060660794779 -0.4617634839447313 RAS(ph)SLNVLNVGGK ddPTM_PC-9_Lapatinib_30min_R1 1 RASSLNVLNVGGK 13 1 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;H0YJK1 Q07866-6 KLC1 Kinesin light chain 1 1 RAS(0.64)S(0.36)LNVLNVGGK 114.27 0.00014086 66888000.0 269190.0 174010.0 208010.0 168710.0 166750.0 165370.0 156580.0 157790.0 188630.0 142640.0 True False 265351.30123660003 173607.0905361424 190908.22074181968 181117.4962000613 156942.09284311382 158297.51059629832 164686.94624817584 165121.4994407153 167384.50303804083 167295.13394414718 1.5861268345389514 1.0377294691314962 1.141146285854052 1.082622619857723 0.938115109166954 0.9462170648020595 0.9844096619281102 0.9870071863288171 1.0005342001992925 1.0 17.35203595725035 -2.337717720118343 1.1603920817485627 0.9946787334531242 199.99999959890866 0.8855444567171281 0.06139260892431353 169.02545342634477 0.888284952628957 0.019027080497150625 88770.63978240291 0.004594965763710568 2.337717720118343 199.00532086545553 RAS(ph)SPGYIDSPTYSR ddPTM_PC-9_AZD4547_30min_R2 1 RASSPGYIDSPTYSR 15 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 RAS(0.638)S(0.362)PGYIDSPTYSR 74.783 0.0071711 13509000.0 4392.3 0.0 3539.4 15573.0 5959.6 5102.5 3491.3 9200.5 4244.3 13722.0 True False 5788.960034484509 0.0 3492.465243397123 11982.885450451571 5132.212410184053 4783.43986838161 3802.0189364557086 7778.774131457218 4468.645033089819 13241.596956651745 0.4371799000857295 0.0 0.2637495503624076 0.9049426205675384 0.38758258743149193 0.3612434273630954 0.2871269189737582 0.587449848905849 0.3374702498285188 1.0 13.692789503394595 -14.522878745280044 0.23340819119413458 4.280531763696628 0.333332447286161 0.40162133634766906 0.22100207211126893 178.73157971326899 1.7830731317559818 277.70369178810347 0.3893963993234801 3.0000000000020256e-15 14.522878745280044 -3.9471993164104666 RAS(ph)SPGYIDSPTYSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RASSPGYIDSPTYSR 15 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 RAS(0.536)S(0.464)PGYIDSPTYSR;RAS(0.565)S(0.435)PGYIDSPTYSR;RAS(0.789)S(0.21)PGYIDS(0.001)PTYSR;RAS(0.5)S(0.5)PGYIDSPTYSR 126.34 3.5057e-05 28112700.0 33011.799999999996 48592.3 42350.6 58106.5 56264.0 54490.6 31438.0 48701.0 42818.4 32048.3 True False 38600.04572722964 53416.22240867696 43360.39891954488 54850.981188814716 45239.473094503446 51633.01701078105 28459.96504859039 47422.65035297485 43444.538095545715 37858.40309579679 1.019589907940813 1.4109475847016766 1.1453309007732275 1.4488456116339603 1.1949651700846868 1.3638456138820492 0.7517476364910421 1.25263208363482 1.1475533710604164 1.0 15.208325937596792 RAS(ph)TAFCPPAASSEAPDGPSSTAR ddPTM_PC-9_AZD4547_30min_R2 2 RASTAFCPPAASSEAPDGPSSTAR 24 1 O00562-2;O00562 O00562-2 PITPNM1 Membrane-associated phosphatidylinositol transfer protein 1 1 RAS(0.5)T(0.5)AFCPPAASSEAPDGPSSTAR;RAS(0.5)T(0.5)AFCPPAASSEAPDGPSSTAR 99.414 1.8441999999999999e-06 11838200.0 38773.0 27920.0 52576.0 78523.0 68341.0 50834.0 45546.0 63308.0 45773.0 61668.0 True False 51102.00747149959 36944.59399464214 51878.80788745184 60420.735518256566 58853.03180152839 47655.34194400991 49599.505765706686 53525.20327311489 48192.46733256842 59509.02209027836 0.8587270581253229 0.6208234095763702 0.871780547977228 1.0153205916675136 0.9889766246241655 0.800808688667648 0.8334787570607628 0.8994468635682552 0.8098346375018207 1.0 15.860820789788077 -5.4618186095800345 10.52140742469262 0.9020382904619616 0.7410770773733839 0.346029065678495 0.09041402189059702 0.7879477198693421 133.21865088738525 0.0239598074848259 0.04983859645063936 3.4528792455218765e-06 5.4618186095800345 -0.1609612130885777 RAS(ph)TAFCPPAASSEAPDGPSSTAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RASTAFCPPAASSEAPDGPSSTAR 24 1 O00562-2;O00562 O00562-2 PITPNM1 Membrane-associated phosphatidylinositol transfer protein 1 1 RAS(0.5)T(0.5)AFCPPAASSEAPDGPSSTAR;RAS(0.5)T(0.5)AFCPPAASSEAPDGPSSTAR 82.21600000000001 3.4325e-05 9897300.0 40635.0 30005.0 40178.0 52438.0 67301.0 60546.0 45793.0 76479.0 52881.0 32352.0 True False 47513.70292216654 32983.69810386321 41135.99589591354 49500.06886628981 54113.85217427096 57370.86117485856 41455.15552739041 74471.50728619883 53654.28458397684 38217.16150170891 1.2432556750726222 0.8630598612717042 1.076374965578595 1.2952314332417485 1.4159568646104503 1.5011805932340938 1.0847261779380635 1.9486404630775305 1.4039317017716673 1.0 15.221933008741813 -5.885461956062056 2.5803768289969966 1.4284289145019895 1.0335864215188035 0.24467348309829873 0.2553359478954694 0.3392371412424217 4.578661927801819 0.07496028111413022 0.12335938863001755 1.301781345855242e-06 5.885461956062056 -0.39484249298318597 RAS(ph)TGAEEQR ddPTM_PC-9_AZD4547_30min_R2 2 RASTGAEEQR 10 1 Q9C0D6 Q9C0D6 FHDC1 FH2 domain-containing protein 1 1 RAS(0.986)T(0.014)GAEEQR;RAS(0.99)T(0.01)GAEEQR 103.97 0.0039242 8442800.0 30252.0 28032.0 24770.0 22209.5 25034.3 24657.5 23509.4 27823.0 31437.0 31072.0 True False 39871.50671930999 37092.79580436277 24441.53361556951 17089.442908354467 21558.719568472825 23115.662627068985 25601.691056257507 23523.59465893527 33098.69564009252 29984.178737580718 1.3297515022259714 1.2370789318258852 0.8151476760287477 0.5699486738629725 0.7190031702103006 0.7709286563882749 0.8538399960966611 0.7845335656784869 1.1038720096278047 1.0 14.871913837680957 -5.230877645815249 4.432124426710733 0.803916939403065 1.3011777390412487 0.62869218982278 0.1399516279005197 0.12293876705681989 5.905527396341551 0.037384595560343 0.10141023976591174 5.876548897640397e-06 5.230877645815249 0.4972607996381837 RAS(ph)TGAEEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RASTGAEEQR 10 1 Q9C0D6 Q9C0D6 FHDC1 FH2 domain-containing protein 1 1 RAS(0.988)T(0.012)GAEEQR;RAS(0.997)T(0.003)GAEEQR 107.97 0.0030789000000000003 11289700.0 19905.4 35927.0 30636.0 21596.0 39759.0 30910.0 22592.9 28145.0 26054.0 28787.0 True False 23274.99107042928 39493.59512672869 31366.478427677004 20386.04613517666 31968.50936236959 29289.02518605489 20452.736953568863 27406.22357209248 26434.990460674588 34005.85522223338 0.6844406917080518 1.1613763238310608 0.9223846370777135 0.5994863532162559 0.9400883804700858 0.8612935917843177 0.601447510139273 0.8059266086086847 0.7773658473788689 1.0 15.05349555452413 -5.548809079345331 24.968154566812714 0.7879788821788024 0.9526516436157131 0.10428172490431398 0.16116033972221236 352.0064955120974 338943.1550405471 0.041737449523890774 0.07229398290119438 2.8261220963823287e-06 5.548809079345331 0.16467276143691068 RAS(ph)TGAEEQR ddPTM_PC-9_Lapatinib_30min_R1 1 RASTGAEEQR 10 1 Q9C0D6 Q9C0D6 FHDC1 FH2 domain-containing protein 1 1 RAS(0.994)T(0.006)GAEEQR 107.97 0.0030789000000000003 5498000.0 8221.2 18124.0 14996.0 14945.0 17025.0 10635.0 16813.0 17218.0 16263.0 15507.0 True False 8103.964180416567 18082.034991535245 13763.086766234006 16044.10515505852 16023.622972437835 10180.165841395852 17683.4948733592 18018.01113739931 14431.289683017834 18187.364288221317 0.4455821114038463 0.9942086552500471 0.7567389396355465 0.8821566941092813 0.8810305175893581 0.5597383810027291 0.9722956330077779 0.9906884170714233 0.7934788930556568 1.0 14.150648862405253 -2.082335118200126 0.17517298538485643 0.9721946482571185 3.934604838811027e-39 0.21842131682740673 0.1617434285597785 91.75301059181587 1.2048845811752003 0.3994251189113617 22.649941697307238 0.008273035383601418 2.082335118200126 -0.9721946482571185 RAS(ph)TVSSVTQVEVDENAYR ddPTM_PC-9_AZD4547_30min_R2 2 RASTVSSVTQVEVDENAYR 19 1 Q7Z628;Q7Z628-2 Q7Z628 NET1 Neuroepithelial cell-transforming gene 1 protein 1 RAS(0.579)T(0.231)VS(0.094)S(0.094)VT(0.002)QVEVDENAYR;RAS(0.487)T(0.487)VS(0.018)S(0.007)VTQVEVDENAYR 102.29 0.00016052 10528700.0 16181.2 21314.8 21871.9 17066.8 17549.4 15611.3 19839.6 25167.0 17075.9 8285.2 True False 21326.485010131513 28204.39226636813 21581.864315154424 13132.31293943151 15112.968734694283 14635.122943119217 21605.28596560211 21278.018430127024 17978.497212859238 7995.137669818613 2.6674318680763065 3.5276931343957716 2.69937369516791 1.6425374373483983 1.8902699814344976 1.8305029315963293 2.702303181990395 2.661369861140835 2.248678879005109 1.0 12.964907160625929 -5.552298966287849 6.496870621796883 2.0868837269115463 3.104102320875917 0.43774056315217946 0.5088800310665846 0.15851700601990742 21.634771323875484 0.1397550975051983 0.24934404536431046 2.803503055149524e-06 5.552298966287849 1.0172185939643708 RAS(ph)TVSSVTQVEVDENAYR ddPTM_PC-9_Lapatinib_30min_R1 2 RASTVSSVTQVEVDENAYR 19 1 Q7Z628;Q7Z628-2 Q7Z628 NET1 Neuroepithelial cell-transforming gene 1 protein 1 RAS(0.394)T(0.394)VS(0.162)S(0.049)VT(0.001)QVEVDENAYR;RAS(0.406)T(0.406)VS(0.138)S(0.048)VT(0.002)QVEVDENAYR 69.024 0.0036816 10427400.0 9111.5 12878.400000000001 12715.8 10876.2 17996.5 15354.8 18568.4 16318.5 17319.699999999997 12390.9 True False 8981.568339155538 12848.580856046545 11670.35600840746 11676.072029939607 16937.98125248033 14698.110997787031 19529.780896121014 17076.71708361312 15368.973001473527 14532.650555163576 0.6180268564955144 0.8841182004119224 0.8030438744885998 0.803437197200823 1.165512181565676 1.011385427730158 1.3438553980217953 1.1750586734878596 1.0575478260579794 1.0 13.827010234209926 -6.250478575613683 9.883239396140116 1.1395660163718535 0.7864494095281962 0.6990369518304484 0.1117010983442336 0.15861648164112416 133.68291026647717 0.03310738022048246 0.041263774860569855 5.617219882449984e-07 6.250478575613683 -0.3531166068436573 RAS(ph)VCAEAYNPDEEEDDAESR ddPTM_PC-9_AZD4547_30min_R2 2 RASVCAEAYNPDEEEDDAESR 21 1 P31323 P31323 PRKAR2B cAMP-dependent protein kinase type II-beta regulatory subunit 1 RAS(1)VCAEAYNPDEEEDDAESR;RAS(1)VCAEAYNPDEEEDDAESR 138.59 2.0793000000000002e-05 28804300.0 27721.0 24485.0 35638.0 47829.0 35216.0 38824.0 34085.0 34078.0 29070.0 31833.0 True False 36535.70136738042 32399.297419728242 35165.41683454444 36802.76300068375 30326.866272407842 36396.32914258647 37118.49896860564 28812.02813453604 30606.580852418778 30718.53635921109 1.189369862552876 1.0547148809716373 1.1447621209335364 1.198063689308826 0.9872497152135373 1.1848327901102251 1.2083420425555365 0.9379362283937928 0.9963554413698898 1.0 14.906821857404996 -7.769812136978792 24.99998503543609 0.9753593419295966 1.1335241755230596 0.5400203357793936 0.06759904967794998 147.88635871657902 441561.61915763724 0.03593777634339693 0.017710205117175862 1.69897842163243e-08 7.769812136978792 0.158164833593463 RAS(ph)VCAEAYNPDEEEDDAESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RASVCAEAYNPDEEEDDAESR 21 1 P31323 P31323 PRKAR2B cAMP-dependent protein kinase type II-beta regulatory subunit 1 RAS(0.948)VCAEAY(0.052)NPDEEEDDAESR 102.24 6.6806e-05 18145000.0 21419.0 19877.0 23741.0 28522.0 32119.0 27634.0 27459.0 21275.0 21553.0 20779.0 True False 25044.813655466598 21850.257197483403 24307.075478243874 26924.004809571652 25825.512518170723 26184.824393123276 24857.884734055697 20716.553792725794 21868.171850729985 24546.06821352651 1.0203187507506903 0.8901734081160283 0.9902635023579486 1.0968764763203396 1.0521242055352538 1.066762471502206 1.0127033184221885 0.8439866463546125 0.8909032461125148 1.0 14.583204331864465 -7.716184879540489 11.499533813433235 0.900635065997069 1.0186706087343853 0.37063729128483236 0.06330994197509313 0.6876519725743981 172.9341079540676 0.03203472804506788 0.01845105125234473 1.9222732413083208e-08 7.716184879540489 0.11803554273731631 RAS(ph)VCAEAYNPDEEEDDAESR ddPTM_PC-9_Lapatinib_30min_R1 2 RASVCAEAYNPDEEEDDAESR 21 1 P31323 P31323 PRKAR2B cAMP-dependent protein kinase type II-beta regulatory subunit 1 RAS(1)VCAEAYNPDEEEDDAESR;RAS(0.987)VCAEAY(0.013)NPDEEEDDAESR 131.9 1.0721e-05 31105000.0 48400.0 53617.0 54995.0 53023.0 58790.0 55530.0 49819.0 52935.0 63121.0 40057.0 True False 47709.80712452707 53492.853130718635 50473.52338683905 56922.48829954279 55332.087785587144 53155.111346752434 52398.38405376089 55394.553348718364 56011.648286402786 46980.79907740254 1.015517148738221 1.1386109683359633 1.0743436548127272 1.2116117524046572 1.1777596139739037 1.1314220360359877 1.1153148750712538 1.1790892116895215 1.1922242572784172 1.0 15.519783631324461 -3.787599713993582 1.223032103426773 1.1465203384738647 1.509272358054067e-07 0.24852546368179207 0.06018886431347695 18.305579280190003 3.587692272387857 0.0168930147745383 46.719043690399076 0.0001630798434992259 3.787599713993582 -1.1465201875466289 RAS(ph)VCSSGGGEHR ddPTM_PC-9_AZD4547_30min_R2 1 RASVCSSGGGEHR 13 1 K7ER94;Q2V2M9-2;Q2V2M9;Q2V2M9-3;Q2V2M9-4 K7ER94 FHOD3 FH1/FH2 domain-containing protein 3 1 RAS(0.999)VCS(0.001)SGGGEHR 85.473 0.0037013000000000007 2815500.0 853.86 1235.4 2820.0 5223.4 3028.7 2387.0 1124.6 4427.1 1964.0 2491.6 True False 1125.3697186086881 1634.7188904362793 2782.6049574447316 4019.225830725534 2608.2172841674683 2237.7405126559333 1224.687221361124 3742.993419637438 2067.8130304145316 2404.3698423840165 0.46805183577450166 0.6798949402956238 1.1573115368497893 1.6716337727561628 1.0847820656331848 0.9306972967341562 0.509358917988592 1.556746118528142 0.8600228608607996 1.0 11.231443114460824 -5.124715311747628 3.696502724823492 1.1086516112947158 0.5082541665933162 0.31386643891191923 0.3146450873907828 0.2850541504060692 6.778633818658202 0.08474162728763014 0.27589767141028926 7.5038594033109785e-06 5.124715311747628 -0.6003974447013996 RAS(ph)VCSSGGGEHR ddPTM_PC-9_Lapatinib_30min_R1 2 RASVCSSGGGEHR 13 1 K7ER94;Q2V2M9-2;Q2V2M9;Q2V2M9-3;Q2V2M9-4 K7ER94 FHOD3 FH1/FH2 domain-containing protein 3 1 RAS(0.999)VCS(0.001)SGGGEHR;RAS(0.998)VCS(0.002)SGGGEHR 67.01899999999999 0.016548 4938100.0 5111.299999999999 2317.0 5892.5 3006.44 3215.7 5073.4 2980.7 1916.6399999999999 4586.7 3115.1000000000004 True False 5038.411924702378 2311.6351288560545 5408.041395707776 3227.5436267898385 3026.558848309448 4856.422508673038 3135.02606132289 2005.694091438322 4070.09754590776 3653.5408843901614 1.3790490059189184 0.632710896635253 1.4802192083887056 0.8834015353652107 0.8283905789149619 1.3292372146216336 0.8580788228530197 0.5489726692282811 1.1140145066659433 1.0 11.835079636353504 -7.479896717750736 24.511052705580745 0.8396010593918998 1.0671277106433072 0.10625553358263717 0.2831262946533534 759.5159490323455 433124.53054658393 0.11230025610298709 0.0757053573838947 3.312098791814064e-08 7.479896717750736 0.22752665125140747 RAS(ph)WASENGETDAEGTQMTPAK ddPTM_PC-9_AZD4547_30min_R2 3 RASWASENGETDAEGTQMTPAK 22 1 Q12789;Q12789-3 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 1 RAS(0.765)WAS(0.207)ENGET(0.027)DAEGTQMTPAK;RAS(0.518)WAS(0.4)ENGET(0.082)DAEGTQMTPAK;RAS(0.749)WAS(0.214)ENGET(0.034)DAEGT(0.002)QMTPAK 94.73 7.980300000000001e-05 53497200.0 129793.0 113880.0 160770.0 203138.0 162429.0 162809.0 139859.0 168958.0 127035.0 150476.0 True False 171064.47413788844 150689.4829552236 158638.0847547481 156307.67255081426 139878.53707862712 152628.52749266825 152306.18005721614 142849.42336859382 133749.81075290745 145207.88104133002 1.1780660451149958 1.0377500303329497 1.0924894958669322 1.0764406961239585 0.9632985212339403 1.0511036067610278 1.0488837035908936 0.9837580601285345 0.9210919530933634 1.0 17.14776023101215 -1.5228787511327542 0.2738708736841859 0.9733874605215771 2.2422193871370757 0.5839447074281328 0.04464940115336856 39.67327964844874 0.5561995721146891 0.052181136664780185 23.90775004110177 0.029999999595729385 1.5228787511327542 1.2688319266154986 RAS(ph)WASENGETDAEGTQMTPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RASWASENGETDAEGTQMTPAK 22 1 Q12789;Q12789-3 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 1 RAS(0.504)WAS(0.489)ENGET(0.007)DAEGTQMTPAK 69.578 0.00074775 16512000.0 27605.0 33957.0 36391.0 36538.0 33159.0 35953.0 39185.0 32963.0 40796.0 36732.0 True False 32277.981276397375 37328.0265460051 37258.69945363606 34490.894317794286 26661.73198387318 34067.561388360766 35473.11312516743 32097.756177185456 41392.564321550606 43391.220829648 0.7438827638226472 0.8602667966534814 0.8586690750166273 0.7948818599320816 0.6144499157685825 0.7851256714372821 0.8175182086817352 0.7397292715777649 0.9539386892121788 1.0 15.405115557086946 -8.360002586080153 4.500109974351174 0.9952722132076401 0.7792785179817684 0.5889561461808268 0.06714965614075666 0.16777291913755513 5.383216862659292 0.06871077653947769 0.018099672117729053 4.3651323294034465e-09 8.360002586080153 -0.21599369522587175 RAS(ph)WASENGETDAEGTQMTPAK ddPTM_PC-9_Lapatinib_30min_R1 2 RASWASENGETDAEGTQMTPAK 22 1 Q12789;Q12789-3 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 1 RAS(0.407)WAS(0.407)ENGET(0.186)DAEGTQMTPAK;RAS(0.743)WAS(0.257)ENGETDAEGTQMTPAK 145.43 3.4486e-05 24387000.0 84065.0 96430.0 107908.0 87250.0 106616.0 113507.0 103406.0 103306.0 110685.0 87073.0 True False 82866.21768436718 96206.72225964171 99036.22077692595 93666.65605746752 100345.05649512097 108652.5702077403 108759.85671055602 108105.97389709445 98218.48973527824 102123.45203252042 0.811431811548821 0.9420629673682146 0.9697696151652672 0.9171904610866474 0.9825858262523957 1.0639335827890026 1.064984139744143 1.0585812734049465 0.9617623354917666 1.0 16.63995468488188 -3.206808666246152 0.4737631768334348 1.0315140323038763 1.170194864195627e-09 0.6750248182766247 0.04228064218222763 12.080034058812002 0.6420468471254859 0.02755695759685522 9.60524706274012 0.0006211426259510314 3.206808666246152 -1.0315140311336815 RAS(ph)YDYNQDR ddPTM_PC-9_AZD4547_30min_R2 1 RASYDYNQDR 10 1 Q96T58;A0A669KB49 Q96T58 SPEN Msx2-interacting protein 1 RAS(0.992)Y(0.008)DYNQDR 71.976 0.014562 8540300.0 9991.9 8272.3 15622.0 14543.0 12300.0 15321.0 11859.0 11619.0 10688.0 9285.0 True False 13169.116355569007 10946.15920135667 15414.842072766529 11190.336037110195 10592.357313454577 14362.975448010697 12914.42802607289 9823.550528058408 11252.94586001554 8959.934976134049 1.4697781167660993 1.2216784195993817 1.7204189666360261 1.248930496361537 1.182191315190199 1.6030222860175156 1.4413528737063548 1.0963863637654414 1.25591825052182 1.0 13.129272547084549 -7.760994999535991 24.99529801218556 1.1321141767311733 1.409167668582344 0.3893596080705959 0.16898847708940518 13.077765373176467 735743.570328501 0.08464528874020863 0.044996245983416866 1.7338239608776935e-08 7.760994999535991 0.2770534918511707 RAS(ph)YDYNQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RASYDYNQDR 10 1 Q96T58;A0A669KB49 Q96T58 SPEN Msx2-interacting protein 1 RAS(0.999)Y(0.001)DYNQDR 75.89 0.010951 5952700.0 9451.0 8377.2 11781.0 11476.0 15468.0 12480.0 11276.0 11156.0 9495.5 11927.0 True False 11050.867634241318 9208.833053013934 12061.903719691303 10833.036925693988 12437.156437967084 11825.526830215616 10207.8556488296 10863.166820759063 9634.353723778895 14089.270685919952 0.7843463214376989 0.653606084963414 0.8561056131702623 0.7688855702460125 0.8827395480729957 0.8393285283413146 0.7245127073206687 0.7710240695151892 0.6838078377901379 1.0 13.78230931376347 -11.899250945787266 2.3729656647797084 2.7502274434879754 0.7761550284606791 0.4887925594128584 0.06935610729823104 4075470.827038124 1045404.4940329385 37591235.152926706 0.018148446911588543 1.2610986309301523e-12 11.899250945787266 -1.9740724150272964 RAS(ph)YDYNQDR ddPTM_PC-9_Lapatinib_30min_R1 2 RASYDYNQDR 10 1 Q96T58;A0A669KB49 Q96T58 SPEN Msx2-interacting protein 1 RAS(0.954)Y(0.045)DY(0.001)NQDR;RAS(1)YDYNQDR 72.681 0.01372 19322700.0 19216.7 15546.3 20381.8 12195.5 20171.4 24885.0 18980.4 23178.0 28678.0 21932.9 True False 18942.66633408881 15510.303497511832 18706.087080023215 13092.397752995386 18984.95791049824 23820.7265597683 19963.112240189537 24254.93449544902 25447.98164727207 25723.972541247793 0.7363818439673222 0.6029513315892956 0.7271850041834883 0.5089570723185165 0.7380258970521097 0.92601275023025 0.7760509076962802 0.9428922557181553 0.989271062487212 1.0 14.650825834151721 -6.634197553622452 3.824545951018029 0.9142221571470863 0.6442223652267395 0.7213762356870286 0.08331738193050835 0.12679030328201787 3.4963865427417677 0.02829355317484996 0.028186954325740563 2.3216804607648586e-07 6.634197553622452 -0.26999979192034684 RASDT(ph)SLTQGIVAFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RASDTSLTQGIVAFR 15 1 Q9H0K1 Q9H0K1 SIK2 Serine/threonine-protein kinase SIK2 1 RAS(0.025)DT(0.812)S(0.128)LT(0.035)QGIVAFR 86.214 0.018914 6081800.0 12508.0 14316.0 11497.0 17463.0 15929.0 12645.0 13967.0 11347.0 12347.0 12078.0 True False 14625.357355739123 15737.197868852047 11771.13208261531 16484.60472580988 12807.826797283262 11981.873939749717 12643.944647676757 11049.153273140295 12527.5515167709 14267.6457906046 1.0250715198838256 1.1029989179585018 0.8250227301245961 1.1553836538796871 0.8976832608023781 0.8397933419148877 0.8861969825465482 0.7744202116663341 0.8780391453942898 1.0 13.800459684481293 -6.499701244613366 23.466013414390577 0.8629690226512404 1.0191574817818259 0.3618983663969183 0.09551563937060278 357.6748339686209 362127.34694336803 0.028229880798756185 0.031759230728590784 3.164453770041732e-07 6.499701244613366 0.15618845913058543 RASEDTTSGS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 1 RASEDTTSGSPPK 13 1 H0YER7;G3V1C3;Q9BZZ5-1;Q9BZZ5-5;Q9BZZ5-2;Q9BZZ5-6;Q9BZZ5 H0YER7 API5 Apoptosis inhibitor 5 1 RASEDTTS(0.036)GS(0.964)PPK 77.468 0.0073738 13254000.0 97116.0 75977.0 64873.0 72166.0 79434.0 71407.0 73304.0 66981.0 64667.0 61129.0 True False 95731.10803110684 75801.07992451295 59539.39235702175 77473.32837871881 74761.84829325274 68353.08906784708 77099.32244077342 70093.18178616243 57383.52148630108 71695.06620072747 1.335253778315578 1.0572705200144417 0.8304531331392735 1.080594976533165 1.042775357566992 0.9533862326938408 1.0753783562304755 0.9776569783744926 0.8003831299303386 1.0 16.129586220754813 -4.800993658364223 3.737264865848151 0.97715310583108 1.365192697803249 0.6013349086004853 0.08898065397029303 0.16680827415021895 4.066931584723707 0.022341955679292123 0.1729770699560975 1.5812711290695167e-05 4.800993658364223 0.388039591972169 RASEDTTSGS(ph)PPKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RASEDTTSGSPPKK 14 2 H0YER7;G3V1C3;Q9BZZ5-1;Q9BZZ5-5;Q9BZZ5-2;Q9BZZ5-6;Q9BZZ5 H0YER7 API5 Apoptosis inhibitor 5 1 RASEDTT(0.005)S(0.073)GS(0.922)PPKK 64.407 0.013207 81741000.0 162600.0 129910.0 143880.0 212370.0 183510.0 175210.0 215460.0 198760.0 172760.0 173460.0 True False 190124.96850361206 142806.60625471993 147310.64486793868 200471.5974128297 147552.53283755732 166021.67916042285 195050.06900468512 193542.76060362818 175286.2881701904 204906.924891396 0.9278601423762589 0.6969340168977196 0.7189149168385389 0.9783544285732798 0.720095394119855 0.8102297140441547 0.951895935718448 0.9445398719746002 0.8554434568919279 1.0 17.64460921592437 -7.253245641212384 21.047012044122415 0.9333481297559663 0.8032483267529901 0.3254105516679522 0.09085656043243388 85.88930004811414 220622.82503056666 0.03481236492008869 0.026357239052338714 5.5815440783960785e-08 7.253245641212384 -0.1300998030029762 RASEDTTSGS(ph)PPKK ddPTM_PC-9_Lapatinib_30min_R1 1 RASEDTTSGSPPKK 14 2 H0YER7;G3V1C3;Q9BZZ5-1;Q9BZZ5-5;Q9BZZ5-2;Q9BZZ5-6;Q9BZZ5 H0YER7 API5 Apoptosis inhibitor 5 1 RASEDT(0.003)T(0.064)S(0.09)GS(0.843)PPKK 46.324 0.040628 113230000.0 437870.0 393680.0 331070.0 347490.0 343240.0 402010.0 348100.0 384310.0 385990.0 345770.0 True False 431625.8935044757 392768.4581476276 303850.7025671568 373045.5737926577 323051.2980358044 384816.96943108103 366122.91473361914 402166.44559263246 342515.74154510605 405535.8837904357 1.0643346514004721 0.9685171493987798 0.7492572537037793 0.9198830207228527 0.7966034842991702 0.9489097877955941 0.9028126224282941 0.9916913932096219 0.8446003306629806 1.0 18.62947005121238 RASGQAFELILS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 6 RASGQAFELILSPR 14 1 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 RASGQAFELILS(1)PR;RASGQAFELILS(1)PR;RASGQAFELILS(1)PR;RAS(0.001)GQAFELILS(0.999)PR;RASGQAFELILS(1)PR;RASGQAFELILS(1)PR 139.29 1.0365e-05 182767000.0 68034.0 62423.6 84693.90000000001 123227.0 89601.3 83738.7 62767.7 87201.20000000001 64370.899999999994 67369.4 True False 89667.3968048901 82600.80793996931 83570.80354798879 94818.91898817156 77161.7061260193 78502.50585133689 68353.90370285313 73726.25822423 67773.41435820317 65010.81781164942 1.3792688636016885 1.2705702023205114 1.285490728483246 1.4585098631258993 1.186905636990657 1.2075298926214995 1.051423532324872 1.134061387103776 1.0424944130768758 1.0 15.988392182377625 -6.852378619777543 1.4004344011820689 1.061929296591952 1.3364352704839662 0.7756444008927453 0.06743423742273988 0.19871106970112826 0.8094906393800011 0.03222102982731225 0.02690435256447678 1.4048222600874924e-07 6.852378619777543 0.27450597389201414 RASGQAFELILS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 RASGQAFELILSPR 14 1 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 RASGQAFELILS(1)PR;RASGQAFELILS(1)PR;RASGQAFELILS(1)PR;RASGQAFELILS(1)PR;RASGQAFELILS(1)PR;RASGQAFELILS(1)PR;RASGQAFELILS(1)PR;RASGQAFELILS(1)PR 156.06 0.00015844 72195900.0 82626.4 69287.79999999999 76442.6 96433.7 122401.3 140339.5 164111.2 155430.7 152169.5 124729.99999999999 True False 96613.41757421203 76166.23487688212 78265.28149417481 91030.83243127372 98417.64393008419 132979.84956643003 148565.3990738032 151350.8088174394 154394.69106108928 147342.5616378635 0.6557061075920965 0.5169330167075719 0.5311790471414101 0.6178176313712263 0.667951220856155 0.9025216345380642 1.008299281771313 1.0272035936868487 1.0478621339607113 1.0 17.16881470450145 -6.786774338577579 1.6706970481918269 1.0297200503646464 0.5677086391854279 0.9657459956818222 0.03841149372826726 0.05909195147119307 0.3415120657905039 0.01669540795770321 0.014910404559682447 1.6339007097343258e-07 6.786774338577579 -0.4620114111792185 RASGQAFELILS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 7 RASGQAFELILSPR 14 1 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 RASGQAFELILS(1)PR;RASGQAFELILS(1)PR;RASGQAFELILS(1)PR;RASGQAFELILS(1)PR;RASGQAFELILS(1)PR;RASGQAFELILS(1)PR;RASGQAFELILS(1)PR 118.23 5.4362e-05 83641700.0 69437.3 58336.29999999999 62652.4 52738.9 85925.9 108396.8 107209.1 102378.09999999999 116945.4 94022.7 True False 68447.11136875865 58201.22588152154 57501.361517257894 56617.49463781299 80871.90749881914 103760.92154928231 112759.86261984504 107134.9602756288 103773.77756234357 110274.39841762751 0.6206981162530403 0.5277854762000497 0.5214389046085807 0.5134237452231941 0.7333697454647974 0.9409339161055535 1.0225389051119975 0.9715306708805688 0.9410504981340727 1.0 16.750738364522142 -6.593551594943888 2.3967530511816646 0.9822916451756902 0.5427923069912176 0.9694071681306811 0.0360506382156006 0.04714673727374335 0.549918245736198 0.013711878305779385 0.014064544307376801 2.549461189359745e-07 6.593551594943888 -0.4394993381844726 RASKAERSFT(ph)EQQNNS(ph) ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RASKAERSFTEQQNNS 16 3 F8VQS4 F8VQS4 SLC16A7 2 RAS(0.043)KAERS(0.127)FT(0.83)EQQNNS(1) 85.469 0.015903999999999998 0.0 8774.6 8528.4 9708.1 12814.0 12941.0 11756.0 11307.0 11494.0 10108.0 7985.8 True False 10259.966473750274 9375.04318976794 9939.57792217427 12096.073123548525 10405.3039477458 11139.494664744774 10235.919104409038 11192.294678899667 10255.810377542746 9433.562324441978 1.0876025536150977 0.9937967087446469 1.0536399273497379 1.282238109797408 1.1030089789925994 1.1808364943837593 1.0850534243981391 1.1864335331628524 1.0871619887399648 1.0 13.203586952414833 -5.551118640041806 24.999993234786945 1.1409772521701191 1.0364541135801073 0.2181439350439336 0.07442124170156615 240.851781698558 213218.24148070993 0.01875110979686116 0.032478650606880655 2.811132783639546e-06 5.551118640041806 -0.10452313859001183 RASPAPSDSSPGEPFVGGPVS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 2 RASPAPSDSSPGEPFVGGPVSSPR 24 1 O60346 O60346 PHLPP1 PH domain leucine-rich repeat-containing protein phosphatase 1 1 RASPAPSDSSPGEPFVGGPVS(0.713)S(0.287)PR;RASPAPSDSSPGEPFVGGPVS(0.736)S(0.264)PR 114.71 9.9541e-09 11995300.0 3973.8999999999996 12019.2 16939.4 18843.0 17003.9 16251.4 9478.6 22025.0 14185.0 16721.5 True False 5237.5175377451405 15904.17135173363 16714.772487992665 14499.037471447946 14643.201993678882 15235.197388930294 10322.177037518717 18621.542334149784 14934.790140748542 16136.085374628483 0.32458414889030845 0.9856276155269046 1.035862918417256 0.8985473945400324 0.9074816880123273 0.9441693592477703 0.6396952419295423 1.1540309747883029 0.925552250995846 1.0 13.978003001807513 -4.758806195890649 24.996770063770658 0.939146586766938 0.32458333276733503 0.6911889323830422 0.12406656630566433 40.703808504512764 386323.4984089927 0.03046552450322713 0.2029794015126754 1.742584328955215e-05 4.758806195890649 -0.6145632539996029 RASPAPSDSSPGEPFVGGPVS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 RASPAPSDSSPGEPFVGGPVSSPR 24 1 O60346 O60346 PHLPP1 PH domain leucine-rich repeat-containing protein phosphatase 1 1 RASPAPSDSSPGEPFVGGPVS(0.5)S(0.5)PR 108.23 0.0007702000000000001 0.0 10847.0 3969.4 9953.3 7408.7 6808.9 8669.8 6874.3 9930.1 9144.8 7500.6 True False 10692.319790903823 3960.209098179208 9134.978094849077 7953.560512698697 6408.413888812453 8299.01286429091 7230.217617791776 10391.488697612314 8114.816324986878 8797.068716078726 1.2154412038820472 0.4501737142215325 1.0384115879591507 0.9041148556861539 0.7284715051843984 0.9433838852619736 0.8218894101141716 1.181244461421497 0.9224454857508535 1.0 13.102807165995491 -7.738325386478119 24.99954092263771 1.0388838338965436 0.860392817845079 0.12337001243338386 0.19724378108114923 411.93239760386314 445536.95761276654 0.08653501456231392 0.0499202665547571 1.826731061489077e-08 7.738325386478119 -0.17849101605146456 RASPAPSDSSPGEPFVGGPVSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RASPAPSDSSPGEPFVGGPVSSPR 24 1 O60346 O60346 PHLPP1 PH domain leucine-rich repeat-containing protein phosphatase 1 1 RASPAPSDSSPGEPFVGGPVS(0.421)S(0.579)PR 86.57700000000001 0.00021513 0.0 3237.7 3245.2 4088.4 6542.9 3953.0 3606.6 7919.4 8476.8 8262.2 3774.4 True False 3785.778662510114 3567.3620092203614 4185.8829613433445 6176.322525368006 3178.4380268479367 3417.463546943561 7169.217100509146 8254.292981912015 8383.019044453269 4458.6688418660415 0.8490827188066495 0.8000957540787779 0.9388189860701719 1.3852391250441223 0.7128670326450388 0.7664761990965189 1.6079276920482586 1.8512908840427424 1.880161846903348 1.0 12.122397335190898 -7.273366025423303 20.174900889932957 1.6557874006237834 0.9179436951407218 0.5665963763417304 0.28693950718747935 39.67686276723624 67114.11906388486 0.11801765367898441 0.08070422007619073 5.328855877058554e-08 7.273366025423303 -0.7378437054830616 RASS(ph)ASVPAVGASAEGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RASSASVPAVGASAEGTR 18 1 V9GYZ0;Q9BZ23-3;Q9BZ23-4;Q9BZ23;A0A2R8YFI4 V9GYZ0 PANK2 Pantothenate kinase 2, mitochondrial 1 RAS(0.261)S(0.725)AS(0.014)VPAVGASAEGTR 96.579 0.00037856 3422500.0 2972.8 3425.3 12002.0 9087.1 10240.0 7977.6 9923.2 10138.0 12124.0 6058.2 True False 3476.0363245236063 3765.3411469809253 12288.17319783847 8577.979247775691 8233.545508455058 7559.240612237835 8983.20265825345 9871.888242098905 12301.290563645442 7156.503703315186 0.485717113918821 0.5261425555102648 1.7170637656689935 1.1986270954910594 1.1504983228948715 1.056275651577751 1.2552501934837348 1.3794289294541748 1.7188966950365694 1.0 12.805039218264962 -5.238295272733279 22.988972152200272 1.3024357400791078 0.5059288846662018 0.65655259320022 0.23243302770812777 172.40404520037103 171246.06473409702 0.05991233373290229 0.15817939710990536 5.777031389231746e-06 5.238295272733279 -0.796506855412906 RASS(ph)LNFLNK ddPTM_PC-9_AZD4547_30min_R2 2 RASSLNFLNK 10 1 Q9H0B6;Q9H0B6-2;A8MZ87 Q9H0B6 KLC2 Kinesin light chain 2 1 RAS(0.23)S(0.77)LNFLNK;RAS(0.058)S(0.942)LNFLNK 112.02 0.00069268 35800000.0 481870.0 406250.0 616850.0 836380.0 695620.0 569120.0 504270.0 717370.0 551720.0 601080.0 True False 635094.6364813545 537562.3678482578 608670.1659573693 643565.5129421871 599045.1702752251 533532.8364318154 549149.0530995665 606516.9500226569 580882.7928412958 580036.3721545116 1.0949220893205922 0.9267735501680927 1.049365514263354 1.1095261329073214 1.0327717347277834 0.9198265178613515 0.9467493410107783 1.0456533057914708 1.0014592545009553 1.0 19.145783844128182 -6.554035689613304 24.772782655405468 0.9825591946898914 1.0412624575909204 0.22825373830848306 0.05529254024243552 307.7999405809505 244728.64504918503 0.019135721876633593 0.019135928335666852 2.7923143639610947e-07 6.554035689613304 0.05870326290102901 RASS(ph)LNFLNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RASSLNFLNK 10 1 Q9H0B6;Q9H0B6-2;A8MZ87 Q9H0B6 KLC2 Kinesin light chain 2 1 RAS(0.081)S(0.919)LNFLNK 133.04 5.7978e-05 38106000.0 265550.0 187060.0 249130.0 326350.0 316040.0 281970.0 284210.0 296990.0 287420.0 223290.0 True False 310502.3701484273 205630.08056352742 255070.20403078583 308065.66754097596 254114.23071212246 267182.996820184 257287.57129778856 289194.32718691585 291622.9737547817 263770.7094373325 1.177167740917031 0.7795789039737244 0.9670148917402301 1.167929783402153 0.9633906329258128 1.0129365667254353 0.9754213113602583 1.0963852954098512 1.1055927110969326 1.0 18.008924843060903 -6.602624566756316 0.6003904433348636 1.056297119316744 0.981099211229881 0.014109233333951976 0.1113625386781623 3.3208320716807243 2.624536723940732 0.08841964222846709 0.11796599273940028 2.496752154116559e-07 6.602624566756316 -0.07519790808686311 RASS(ph)LNFLNK ddPTM_PC-9_Lapatinib_30min_R1 1 RASSLNFLNK 10 1 Q9H0B6;Q9H0B6-2;A8MZ87 Q9H0B6 KLC2 Kinesin light chain 2 1 RAS(0.086)S(0.914)LNFLNK 109.95 0.00082942 26772000.0 333050.0 267050.0 287760.0 241800.0 268230.0 247490.0 225130.0 246930.0 296910.0 203190.0 True False 328300.64592611045 266431.6621325028 264101.48358572205 259582.77862115388 252453.23876047003 236905.42962736834 236786.12983045008 258403.26926228442 263468.8691990915 238311.12076634317 1.377613620675299 1.1179992829362377 1.1082213987179623 1.0892600302764173 1.0593430887683701 0.9941014454782702 0.9936008402336025 1.084310578672663 1.1055668252150714 1.0 17.86248675076611 -1.5228828009236943 0.9217787907257656 1.0451728382841217 191.1924037978849 0.8531130440905916 0.04047902872997987 395.868862449469 0.7874305045571697 0.014198499731341166 158515.8289424455 0.029999719847390027 1.5228828009236943 190.1472309596008 RASS(ph)LNVLNVGGK ddPTM_PC-9_AZD4547_30min_R2 1 RASSLNVLNVGGK 13 1 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;H0YJK1 Q07866-6 KLC1 Kinesin light chain 1 1 RAS(0.096)S(0.904)LNVLNVGGK 149.22 0.00017683 40623000.0 54380.0 56948.0 84674.0 133370.0 97359.0 81524.0 79509.0 85459.0 64241.0 75994.0 True False 71671.70882573297 75355.32732116326 83551.16743499115 102623.60704595942 83842.38338866868 76426.29139244328 86585.14697065753 72253.2752024565 67636.64810939923 73333.47319077338 0.9773396200570317 1.0275706855603324 1.1393319285128762 1.3994101544732405 1.143303047580426 1.042174713225761 1.1807042978233224 0.9852700555242107 0.9223161697721021 1.0 16.162184248894356 -7.840283739876963 5.926257081669513 0.9603564672174333 1.1337001165966758 0.3109905312850445 0.10968752162797518 0.2738202102719291 15.659106530013652 0.06678384094283488 0.03170917457182873 1.4444957224719145e-08 7.840283739876963 0.17334364937924251 RASS(ph)LNVLNVGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RASSLNVLNVGGK 13 1 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;H0YJK1 Q07866-6 KLC1 Kinesin light chain 1 1 RAS(0.004)S(0.996)LNVLNVGGK 160.78 0.00043234 29761000.0 37534.0 31223.0 36565.0 48708.0 57534.0 59716.0 49691.0 51835.0 53339.0 43065.0 True False 43887.76486970832 34322.61309438164 37436.84827353473 45979.04867346665 46260.62571127475 56584.38783599006 44983.90874831429 50474.38617372232 54118.98196752597 50872.343597647596 0.8627038144108177 0.674681185632831 0.735897849912813 0.9038122764132451 0.9093472492077974 1.1122819165462352 0.8842507650934014 0.9921773325979879 1.063819319895231 1.0 15.634593937654499 -6.043475305104889 1.9262325238753764 0.9983802481585108 0.7487075201410591 0.6619079048142452 0.07534405903631086 0.19643884399133257 1.4553517123485131 0.024249137045304743 0.037575202006857315 9.047418817964617e-07 6.043475305104889 -0.24967272801745166 RASS(ph)LNVLNVGGK ddPTM_PC-9_Lapatinib_30min_R1 1 RASSLNVLNVGGK 13 1 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;H0YJK1 Q07866-6 KLC1 Kinesin light chain 1 1 RAS(0.039)S(0.961)LNVLNVGGK 147.75 5.1178000000000004e-05 73650000.0 263900.0 179410.0 229400.0 175680.0 186970.0 183710.0 162710.0 150460.0 206540.0 144480.0 True False 260136.73760666733 178994.5871679177 210539.61750960755 188600.0932513 175972.79219716313 175853.15154892654 171134.32765385555 157450.92088123446 183277.29023737958 169453.17549250153 1.5351541028995273 1.0563070691811165 1.2424648691161537 1.1129923809521394 1.038474443961955 1.037768404385601 1.009921042532652 0.929170671624279 1.0815807358268703 1.0 17.370527147106216 -1.5228787452803376 0.6479263741352481 1.0181332644845908 40.55848960872142 0.7443611203745386 0.0825914628991513 110.01351692827402 0.7158689394612883 0.03405880792817422 6236.438199686141 0.029999999999999995 1.5228787452803376 39.540356344236834 RASS(ph)PGYIDSPTYSR ddPTM_PC-9_AZD4547_30min_R2 3 RASSPGYIDSPTYSR 15 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 RAS(0.052)S(0.948)PGYIDSPTYSR;RAS(0.316)S(0.589)PGYIDS(0.095)PTYSR;RAS(0.315)S(0.684)PGYIDS(0.001)PTYSR 171.78 0.00017056 42439000.0 31402.0 25718.7 42273.0 62122.0 52897.0 39097.7 34931.0 52685.1 41538.7 43551.2 True False 41387.18279782405 34031.76681840983 41712.4323993125 47800.73267533244 45553.164618683484 36652.91463831917 38039.79132968647 44543.82837815732 43734.35087906323 42026.485743953584 0.9847880941074995 0.8097695112017791 0.9925272518250883 1.1373954264593633 1.083915626355632 0.8721384619600863 0.9051385252967366 1.0598989563281747 1.04063782885666 1.0 15.359011202878703 -5.494290487708854 22.90619217351158 1.0133995468673302 0.8982460537028897 0.2319008336853291 0.08391896614928962 376.96331155531243 302037.1930575113 0.02366302111920275 0.04903700144675111 3.204125455655287e-06 5.494290487708854 -0.11515349316444057 RASS(ph)PGYIDSPTYSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RASSPGYIDSPTYSR 15 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 RAS(0.369)S(0.631)PGYIDSPTYSR;RAS(0.284)S(0.716)PGYIDSPTYSR;RAS(0.064)S(0.936)PGYIDSPTYSR;RAS(0.289)S(0.663)PGY(0.001)IDS(0.046)PT(0.001)YSR 99.663 0.0013077 27640500.0 31693.4 23424.800000000003 25860.7 40936.1 39197.0 50543.0 34607.5 51922.1 42274.0 26073.7 True False 37058.466646816596 25750.25933489001 26477.3171652509 38642.58303362687 31516.629228018835 47892.43610413366 31329.227063397517 50559.19989101235 42892.17727544933 30800.655410704356 1.2031713660851977 0.8360295906541279 0.8596348620571581 1.254602621871389 1.0232454085073024 1.5549161362160262 1.0171610521154515 1.6414975336349882 1.3925735249303406 1.0 14.910673430070682 -6.295560943847574 1.4203999521242443 1.337591599654304 0.9698404934080714 0.24459892379736914 0.2314651347480198 0.5037620708104634 2.0454904724123444 0.0857779537044861 0.1158107836414374 5.063362911791776e-07 6.295560943847574 -0.36775110624623253 RASS(ph)PGYIDSPTYSR ddPTM_PC-9_Lapatinib_30min_R1 2 RASSPGYIDSPTYSR 15 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 RAS(0.223)S(0.777)PGYIDSPTYSR;RAS(0.211)S(0.788)PGYIDS(0.001)PTYSR 113.11 0.00036561 30922000.0 47929.0 37001.0 49670.0 26996.0 33221.0 26545.2 35538.0 27919.0 37595.0 36900.0 True False 47245.52367089785 36915.32645783468 45586.324331744654 28981.375896016012 31267.00609499898 25409.923675883518 37377.98375123051 29216.218663320462 33360.655207099284 43278.11583384065 1.0916723789984162 0.8529790575810907 1.0533343111970492 0.6696542891859094 0.7224668979362134 0.5871310057360358 0.8636693865032676 0.6750806522051797 0.7708435213580495 1.0 15.401350070573114 -5.761463994423235 24.9999999999964 0.7381202067926345 0.9846936537703717 0.44756502640320484 0.12272879286049793 0.5484208548843281 557326.4495093771 0.031786024651149346 0.050796781738095285 1.7319526138957865e-06 5.761463994423235 0.2465734469777372 RASWAS(ph)ENGETDAEGTQMTPAK ddPTM_PC-9_AZD4547_30min_R2 1 RASWASENGETDAEGTQMTPAK 22 1 Q12789;Q12789-3 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 1 RAS(0.429)WAS(0.521)ENGET(0.039)DAEGT(0.012)QMTPAK 65.155 0.0013888 7107100.0 19910.0 23427.0 32256.0 37182.0 27538.0 25179.0 29244.0 31473.0 22638.0 26991.0 True False 26240.965846273382 30999.3196100459 31828.264364303992 28610.264356173535 23714.82404048065 23604.553149628697 31846.659346865297 26609.5710275912 23834.598463607017 26046.053305421006 1.0074833810161867 1.1901733919738988 1.2219995095256726 1.0984491208969014 0.9104958729215549 0.9062621838647563 1.222705757890659 1.0216354361085833 0.9150944361557566 1.0 14.668777160572818 -6.012363257659932 23.03594437324992 1.0040058583362412 1.1474659290137097 0.30036063631923726 0.10066477785627799 275.34473987263135 513043.4204957314 0.030541543349891148 0.0416578809265448 9.719339273703439e-07 6.012363257659932 0.14346007067746847 RASWAS(ph)ENGETDAEGTQMTPAK ddPTM_PC-9_Lapatinib_30min_R1 1 RASWASENGETDAEGTQMTPAK 22 1 Q12789;Q12789-3 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 1 RAS(0.374)WAS(0.572)ENGET(0.054)DAEGTQMTPAK 109.42 9.806e-06 10296000.0 58620.0 63807.0 67626.0 48580.0 65250.0 72293.0 66590.0 64883.0 77991.0 55897.0 True False 57784.0680504086 63659.25881179038 62066.05132390913 52152.735258129316 61412.12328643579 69201.19691321392 70037.70437262756 67897.70104703675 69206.83229836098 65558.7219719294 0.8814093123284236 0.9710265376900984 0.9467245464376847 0.7955117746264153 0.936749854774944 1.0555604934282299 1.0683201603993433 1.035677618549502 1.0556464527785276 1.0 16.000500109784085 -6.684006750833634 4.675062249358079 1.0469511324396261 0.9030561124344217 0.685721451789354 0.046655629114508726 0.12668787390173475 5.0895288575387765 0.01640618098536564 0.01616318137928042 2.0701091700003623e-07 6.684006750833634 -0.14389502000520438 RAT(ph)EKIS(ph)EDLR ddPTM_PC-9_Lapatinib_30min_R1 1 RATEKISEDLR 11 2 Q5SV16;Q5T2N8;Q9NVI7-3;Q9NVI7-2;Q9NVI7 Q5SV16 ATAD3A;ATAD3C ATPase family AAA domain-containing protein 3C;ATPase family AAA domain-containing protein 3A 2 RAT(1)EKIS(1)EDLR 83.87700000000001 0.019177 0.0 9949.1 6281.1 8618.6 8825.3 6265.8 8485.2 5313.1 5793.3 6656.7 4512.8 True False 9807.224009558515 6266.556498859633 7910.011976758087 9474.342002337758 5897.257963036767 8122.307775967292 5588.186320802038 6062.477867481439 5906.952347841408 5292.831467071983 1.8529258055110365 1.183970534079053 1.494476449130911 1.7900328134912267 1.1141971928872234 1.5345865113027277 1.0558028071680594 1.1454129807830868 1.1160287994412863 1.0 12.369824001455495 -7.0972471384043905 0.8508904425604061 1.0422963697017815 1.5377369926786335 0.46109657245931035 0.21848702404201562 0.589979473353422 0.8676430376939662 0.1579561905380771 0.10712488057388671 7.9937923303977e-08 7.0972471384043905 0.495440622976852 RAT(ph)ISSPLELEGTVSR ddPTM_PC-9_AZD4547_30min_R2 2 RATISSPLELEGTVSR 16 1 Q96GS4 Q96GS4 C17orf59 Uncharacterized protein C17orf59 1 RAT(0.963)IS(0.036)S(0.001)PLELEGTVSR;RAT(0.994)IS(0.005)S(0.001)PLELEGTVSR 150.61 2.6246e-05 15357700.0 18478.3 15200.800000000001 22181.0 28705.0 24845.0 17570.9 18671.6 23377.3 19473.3 24758.0 True False 24354.015027483347 20114.16133215459 21886.86544719207 22087.505737829073 21395.700605916976 16472.18884533981 20333.33622831794 19764.875441912372 20502.618882470117 23891.2299557487 1.0193705000785567 0.8419056435943235 0.9161045910039328 0.9245026638954763 0.8955462169819662 0.689465920166085 0.8510795076678479 0.8272858064871857 0.858165063935387 1.0 14.544193507323715 -4.757496801140331 24.93261906600413 0.8598797119310277 1.0193707382222057 0.2576592520926717 0.07664844202850937 155.31744995393433 982076.2119308321 0.019343070672390075 0.14295048969288685 1.7478461363877387e-05 4.757496801140331 0.15949102629117795 RAT(ph)ISSPLELEGTVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RATISSPLELEGTVSR 16 1 Q96GS4 Q96GS4 C17orf59 Uncharacterized protein C17orf59 1 RAT(0.997)IS(0.002)SPLELEGTVSR;RAT(0.719)IS(0.237)S(0.044)PLELEGTVSR;RAT(0.768)IS(0.226)S(0.006)PLELEGTVSR 134.04 3.3669e-06 12961400.0 24781.5 24220.199999999997 21622.0 22456.0 24577.0 13203.8 14431.599999999999 23125.9 18537.100000000002 11497.400000000001 True False 28976.518493064355 26624.62139027454 22137.550481891627 21197.8631233343 19761.3132774707 12511.36948403854 13064.534372264032 22518.869628916473 18808.170018752226 13581.787606631686 2.1334834067730353 1.960317902282195 1.6299437984939738 1.5607564878266726 1.4549861807455808 0.921187243270504 0.9619156734482366 1.6580195686406558 1.384808138920433 1.0 13.729385756149453 -5.494502414237988 0.946699025653929 1.2250734396571394 2.2110046299024653 0.6858877374184007 0.21975358474388024 0.5643886006348842 0.797126830339944 0.09226272367202747 0.45672574191216975 3.2025622915729112e-06 5.494502414237988 0.9859311902453258 RAT(ph)ISSPLELEGTVSR ddPTM_PC-9_Lapatinib_30min_R1 2 RATISSPLELEGTVSR 16 1 Q96GS4 Q96GS4 C17orf59 Uncharacterized protein C17orf59 1 RAT(0.755)IS(0.239)S(0.006)PLELEGTVSR;RAT(0.993)IS(0.007)SPLELEGTVSR 167.9 2.6388000000000002e-05 14423500.0 23300.8 20516.1 22775.0 16878.9 11716.7 12323.7 15833.4 6265.1 14571.9 13242.1 True False 22968.526319156605 20468.596230955412 20902.527414042357 18120.230612359803 11027.546741918495 11796.644078947818 16653.175978578798 6556.1994178720215 12930.659173090311 15530.979341010867 1.478884609581977 1.3179205110978642 1.3458602291001356 1.166715260802118 0.7100355038654468 0.7595557124847743 1.0722553686363279 0.42213689645184327 0.8325720412843387 1.0 13.922861184540103 -6.067751900262206 2.860698286899067 0.7816274253453988 1.373309631694921 0.7064926980649686 0.1700969363978265 0.14389391356977288 2.3162378823576075 0.05191013901509325 0.07368962590857427 8.555553270459434e-07 6.067751900262206 0.5916822063495222 RATASEQPLAQEPPAS(ph)GGSPATTK ddPTM_PC-9_AZD4547_30min_R2 1 RATASEQPLAQEPPASGGSPATTK 24 1 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 RATASEQPLAQEPPAS(0.776)GGS(0.213)PAT(0.009)T(0.001)K 126.25 9.1595e-08 8975300.0 16129.0 12446.0 18658.0 22817.0 23793.0 19221.0 15812.0 20706.0 18283.0 17441.0 True False 21257.686495958962 16468.92610520474 18410.58272907938 17556.893169135907 20489.752647075184 18019.107831487094 17219.237368097187 17506.363476545088 19249.402054515725 16830.39589862723 1.2630532652944215 0.978522799130829 1.093888868685557 1.04316578616953 1.2174254705883911 1.0706288752813486 1.02310352482568 1.040163498350802 1.1437284167561264 1.0 14.038781492893989 -8.107924195881845 0.011513746167050445 4.148176845955294e-07 2.1342933837744806 0.1291949688488806 0.08297966380999365 1885.735558713995 21.07742989023173 1960.0786762061502 1942.8758131165728 7.799662381870244e-09 8.107924195881845 2.134292968956796 RATASEQPLAQEPPASGGS(ph)PATTK ddPTM_PC-9_AZD4547_30min_R2 2 RATASEQPLAQEPPASGGSPATTK 24 1 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 RATASEQPLAQEPPAS(0.174)GGS(0.778)PAT(0.039)T(0.009)K;RATASEQPLAQEPPAS(0.014)GGS(0.959)PAT(0.02)T(0.007)K 148.8 4.0341000000000004e-07 41573000.0 93115.0 72820.0 95265.0 134815.0 108126.0 96320.0 91284.0 95355.0 76995.0 100173.0 True False 122723.63308768171 96357.64092728645 94001.72385495466 103735.48462098691 93114.57129061682 90297.09517344765 99408.09915946003 80620.07578991394 81064.79851159219 96665.9737602884 1.2695639252754118 0.9968103271398626 0.9724385965226965 1.0731333951927018 0.9632610904176239 0.9341145768351308 1.0283670178088884 0.8340067621915757 0.838607375048185 1.0 16.560720532685053 -1.5228787452803376 0.8410376758055935 0.9421403862427222 102.9228215159493 0.6271392902270707 0.07175150487039554 450.4343237420562 1.3031421105585572 0.026425130586856523 87830.0533077478 0.029999999999999995 1.5228787452803376 101.98068112970657 RATASEQPLAQEPPASGGS(ph)PATTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RATASEQPLAQEPPASGGSPATTK 24 1 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 RATASEQPLAQEPPAS(0.475)GGS(0.515)PAT(0.007)T(0.002)K;RATASEQPLAQEPPAS(0.173)GGS(0.752)PAT(0.058)T(0.017)K;RATASEQPLAQEPPAS(0.201)GGS(0.77)PAT(0.024)T(0.004)K;RATASEQPLAQEPPAS(0.123)GGS(0.827)PAT(0.041)T(0.009)K 131.97 4.9328e-09 42662800.0 141035.0 110401.0 127374.0 143778.0 162769.0 147029.0 143036.0 128633.0 121644.0 99696.0 True False 164909.43993177693 121360.88166520905 130411.07922858474 135722.58479456496 130875.58289704347 139318.54041023806 129486.59458903792 125256.52004792937 123422.81337216143 117770.09560689818 1.400265823696229 1.0304897948821954 1.1073361073245673 1.1524367378251092 1.1112802636578454 1.1829704280385904 1.0994861974235628 1.0635681273964483 1.047997904188949 1.0 16.8456137284046 -4.753692864641294 24.993850585208516 1.0969929516517434 1.4002663696101834 0.7553839039318471 0.0530391633948119 142.9939325865961 461327.26696818136 0.013385328752435427 0.1406682688164533 1.763222565928112e-05 4.753692864641294 0.30327341795844 RATASEQPLAQEPPASGGS(ph)PATTK ddPTM_PC-9_Lapatinib_30min_R1 4 RATASEQPLAQEPPASGGSPATTK 24 1 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 RATASEQPLAQEPPAS(0.025)GGS(0.915)PAT(0.051)T(0.009)K;RATASEQPLAQEPPAS(0.004)GGS(0.884)PAT(0.085)T(0.027)K;RATASEQPLAQEPPAS(0.207)GGS(0.775)PAT(0.014)T(0.004)K;RATASEQPLAQEPPAS(0.37)GGS(0.616)PAT(0.011)T(0.003)K 142.79 4.245e-09 59475700.0 191384.0 133473.0 166805.0 143140.0 135058.0 140374.0 98091.2 102809.0 132620.0 95206.3 True False 188654.82906447284 133163.95146905683 153090.93678592003 153666.99310104235 127114.1539742443 134370.53124777653 103169.88237207218 107585.88146270695 117682.93904948814 111662.58210057938 1.689508029597087 1.1925566198094024 1.3710137622290008 1.3761726642021206 1.1383773470306016 1.2033622071066123 0.9239431905590589 0.9634908976562948 1.0539156164549908 1.0 16.768786297127726 -5.947967171087855 0.47700281970432906 0.9511858178138488 1.601215657215729 0.7072787860786451 0.12055308815749038 0.9975311805011248 0.3742598892164702 0.09816818019421188 0.3276845231948869 1.1272826657889236e-06 5.947967171087855 0.6500298394018802 RATLGPTPT(ph)TPPQPPDPSQPPPGPMQH ddPTM_PC-9_AZD4547_30min_R2 1 RATLGPTPTTPPQPPDPSQPPPGPMQH 27 1 Q5SRK2;O60927 Q5SRK2 PPP1R11 Protein phosphatase 1 regulatory subunit 11 1 RAT(0.015)LGPT(0.138)PT(0.476)T(0.37)PPQPPDPS(0.001)QPPPGPMQH 56.681000000000004 0.0016090999999999998 13389000.0 8253.6 4137.7 10659.0 14058.0 12692.0 10332.0 9558.4 12223.0 9197.7 7780.7 True False 10878.073114455146 5475.130607866434 10517.654695533125 10817.145293934896 10929.934879867105 9685.938406686673 10409.079082925628 10334.216206597639 9683.87164452329 7508.300061260762 1.4488063910206255 0.7292104155660334 1.4008037251733176 1.440691661984341 1.4557136489869849 1.2900308095918387 1.3863429801682405 1.3763722976279615 1.2897555459307541 1.0 12.874270591762496 -11.703692358635983 1.8777830219189005 0.3228339130436346 1.3097750179494598 0.17542597707022434 0.2035182790635353 3651893.644133734 710453.6528976656 10491319.661958408 0.05688943486104321 1.9783705630513325e-12 11.703692358635983 0.9869411049058252 RATLGPTPTT(ph)PPQPPDPSQPPPGPMQH ddPTM_PC-9_Lapatinib_30min_R1 1 RATLGPTPTTPPQPPDPSQPPPGPMQH 27 1 Q5SRK2;O60927 Q5SRK2 PPP1R11 Protein phosphatase 1 regulatory subunit 11 1 RAT(0.203)LGPT(0.203)PT(0.158)T(0.435)PPQPPDPSQPPPGPMQH 48.291000000000004 0.011999 11216000.0 7163.8 5844.1 5865.8 5017.4 7254.5 5409.9 5804.3 5325.5 4913.9 2275.9 True False 7061.642898319974 5830.568345510435 5383.536566642799 5386.396333555743 6827.80457289576 5178.5311880928475 6104.818253341979 5572.942171693576 4360.44483633901 2669.286282553874 2.6455172472409574 2.184317352401768 2.0168449528358683 2.0179163129712108 2.557913932844689 1.9400433823599545 2.287060137851199 2.0878023493087414 1.6335620741912698 1.0 11.382238328347938 -8.529160543660646 1.6304316589937535 1.001270512807482 2.2228490782910004 0.7653998054173745 0.21534815448815178 0.1882132566260024 1.1156648548844117 0.20247772961091115 0.0587070403525974 2.956919193657279e-09 8.529160543660646 1.2215785654835185 RAVS(ph)PSNPK ddPTM_PC-9_AZD4547_30min_R2 2 RAVSPSNPK 9 1 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 RAVS(0.999)PS(0.001)NPK;RAVS(0.993)PS(0.007)NPK 107.34 0.0011501 36511400.0 55312.0 62336.0 91209.0 116232.0 111772.0 97645.0 111061.0 121069.0 97673.0 117291.0 True False 72900.06543892885 82484.89295308065 89999.509065098 89436.50816649887 96254.38712515801 91539.2427139878 120945.21384633426 102360.56793885065 102835.79537661844 113184.67779060209 0.6440806906196085 0.7287637740656228 0.7951562951975008 0.7901821157450424 0.8504188818139674 0.8087600238906936 1.0685652528877592 0.9043677106915776 0.9085664012479705 1.0 16.788319143104125 -4.302759396052351 0.2753495352363749 1.0015745080577556 0.2675175463660156 0.7582354719439399 0.05860145189869067 5.70981430055173 0.2927690999283541 0.07458652532432421 1.4825413746757885 4.980129132294617e-05 4.302759396052351 -0.7340569616917401 RAVS(ph)PSNPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RAVSPSNPK 9 1 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 RAVS(0.992)PS(0.008)NPK;RAVS(0.991)PS(0.009)NPK;RAVS(0.944)PS(0.056)NPK;RAVS(0.993)PS(0.007)NPK;RAVS(0.993)PS(0.007)NPK 87.667 0.0055111000000000005 29013100.0 218586.0 209004.0 280422.0 291623.0 345281.0 310213.0 311012.0 334685.0 278907.0 248085.0 True False 255588.29252970853 229752.53586068386 287108.32398635667 275284.3087645225 277625.6666703972 293944.8841812239 281550.69182811223 325899.87337806914 282985.4872347951 293060.84666022 0.872133877460752 0.7839755411853534 0.9796884410125083 0.9393418189489231 0.9473311424377389 1.003016566460783 0.9607243513991043 1.112055319201078 0.9656202473300487 1.0 18.16084070925958 -5.380601219215836 0.5975853372642299 1.0193436371633837 0.7716819646966973 0.5580826344064322 0.05406858370496406 1.4023243780738486 0.6161135438892076 0.030043373919953913 0.21849858287761315 4.162926861059779e-06 5.380601219215836 -0.24766167246668647 RAVS(ph)PSNPK ddPTM_PC-9_Lapatinib_30min_R1 1 RAVSPSNPK 9 1 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 RAVS(0.989)PS(0.011)NPK 56.086999999999996 0.040437 24539000.0 58981.0 49530.0 61295.0 49281.0 44254.0 53779.0 37358.0 37790.0 48386.0 35430.0 True False 58139.92012420928 49415.31632811411 56255.56170554231 52905.289136596744 41651.06672671157 51478.99753497206 39292.21444590215 39545.861359177616 42936.25915283165 41554.02829249254 1.3991404086018122 1.1891823334259473 1.3537932185435284 1.2731687229985114 1.0023352353118689 1.2388449363469447 0.9455693240936878 0.951673351156722 1.033263462464091 1.0 15.34270071974367 -6.475899419545159 0.8360795801486638 0.9804663650381376 1.3283804950733957 0.674804710003972 0.09300326531157223 0.37055570876833627 0.5712090080236157 0.05283301413347714 0.06856837221053465 3.3427244690829166e-07 6.475899419545159 0.3479141300352582 RAVSEGCAS(ph)EDEVEGEA ddPTM_PC-9_Lapatinib_30min_R1 1 RAVSEGCASEDEVEGEA 17 1 Q9BYX2-4;Q9BYX2-2;Q9BYX2;Q9BYX2-6;Q9BYX2-5 Q9BYX2-4 TBC1D2 TBC1 domain family member 2A 1 RAVS(0.063)EGCAS(0.937)EDEVEGEA 62.236999999999995 0.043338 14179000.0 26488.0 32760.0 38734.0 35111.0 39821.0 29189.0 22802.0 24612.0 35595.0 21984.0 True False 26110.27626269572 32684.146232768384 35549.44003756386 37693.18006686246 37478.80707109822 27940.654512882338 23982.575988957124 25755.5633705234 31585.916268032972 25783.90510816131 1.012657941191038 1.2676181554214205 1.3787453796636682 1.4618879455514104 1.4535737280244316 1.0836471200027167 0.93013745933179 0.9989007973183651 1.2250245312156058 1.0 14.654183163556093 -6.879785312152133 6.43182401555013 1.0345492101782916 1.323060041761766 0.48719808270742193 0.13744826541721966 0.19346256041060997 10.142608777423085 0.05207643532891223 0.04594778515961656 1.3189085627852172e-07 6.879785312152133 0.28851083158347435 RAVVVS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 RAVVVSPK 8 1 G3V5E1;O75909-1;O75909 G3V5E1 CCNK Cyclin-K 1 RAVVVS(1)PK;RAVVVS(1)PK;RAVVVS(1)PK 62.633 0.028047000000000002 30566800.0 285282.0 254449.0 180953.0 184499.0 219892.0 208510.0 200134.0 216363.0 175128.0 189201.0 True False 281213.82636568876 253859.8389737997 166075.74283877944 198067.6719306214 206958.38488430541 199592.51336055022 210495.9592568171 226416.01485196457 155403.2404604037 221904.140755514 1.2672761554076633 1.1440067684608612 0.7484120948502521 0.8925821359451117 0.9326476927364988 0.8994537581903623 0.9485895961208491 1.0203325367480258 0.7003169924243162 1.0 17.75957706307002 -5.077048622875656 5.078729686457024 0.8978757851341372 1.2419705506902912 0.6392915023327884 0.09583056333836579 0.11516868395750067 5.231173035670346 0.023753091254529034 0.06978941758747159 8.37435519013876e-06 5.077048622875656 0.3440947655561539 RCAT(ph)PVIIDEILPSKK ddPTM_PC-9_AZD4547_30min_R2 2 RCATPVIIDEILPSKK 16 2 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 RCAT(1)PVIIDEILPSKK;RCAT(1)PVIIDEILPSKK 106.28 0.00048983 14131200.0 105499.0 111772.0 128718.0 203505.0 170363.0 151085.0 120581.0 183348.0 134045.0 149010.0 True False 139045.4874844802 147900.11317941055 127011.11521715294 156590.06637090765 146711.0381294362 141637.631066033 131312.4754036505 155015.77951789767 141130.3450417089 143793.20525511395 0.9669823218544265 1.0285612099473702 0.8832901039504149 1.0889948943908014 1.0202918689318143 0.9850092069005862 0.9132036188405391 1.0780466242676274 0.981481320979801 1.0 17.13363597930752 -5.7634864786131255 24.999984671022638 1.008234733136335 0.9665062317152622 0.13473168168745175 0.057158689459734825 132.42295103521698 1617231.4092956716 0.015886230047708765 0.024974583047923746 1.7239057625214496e-06 5.7634864786131255 -0.04172850142107287 RCAT(ph)PVIIDEILPSKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RCATPVIIDEILPSKK 16 2 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 RCAT(1)PVIIDEILPSKK;RCAT(1)PVIIDEILPSKK 72.615 0.007536 9760800.0 78351.0 54892.0 83274.0 105388.0 112334.0 98632.0 100535.0 97821.0 94607.0 68191.0 True False 91614.27679721122 60341.31499141006 85259.56797840375 99483.4520325058 90322.95909636638 93459.56428828735 91011.59698963164 95253.30239991663 95990.44839614029 80553.48850034083 1.1373098608488394 0.7490838213810536 1.058421796072097 1.234998680809272 1.121279298735575 1.1602174657884856 1.129828126428647 1.182485130976216 1.191636143675319 1.0 16.297659448098457 -5.517730317936963 24.594700624347187 1.1518679062781503 0.9333358199780148 0.37240162450241043 0.10466081027827964 144.7333877735893 691408.1446513395 0.02570595029401913 0.046246576738103194 3.0357757122117542e-06 5.517730317936963 -0.21853208630013543 RCAT(ph)PVIIDEILPSKK ddPTM_PC-9_Lapatinib_30min_R1 2 RCATPVIIDEILPSKK 16 2 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 RCAT(1)PVIIDEILPSKK;RCAT(1)PVIIDEILPSKK 91.712 0.0015115 13320800.0 96962.0 68160.0 95183.0 69460.0 76131.0 68830.0 59103.0 56820.0 70681.0 52951.0 True False 95579.30409934683 68002.17970773802 87357.42115700529 74568.32011176752 71653.12425930491 65886.30135056676 62163.064146799974 59460.064631608104 62720.161476073554 62103.509797227496 1.5390322448992053 1.0949812648233588 1.4066422564881382 1.2007102393284783 1.1537693198541854 1.0609110751661277 1.00095895304093 0.9574348507153552 1.009929417529854 1.0 15.92238718461304 -6.368809905723006 0.817565725893807 0.9740312352871814 1.356643432690379 0.6692551880150329 0.1047263458385613 0.3862115463761957 0.5650797249000423 0.05575953484455408 0.08285711314384236 4.2775007491763955e-07 6.368809905723006 0.3826121974031975 RCDDLTR ddPTM_PC-9_AZD4547_30min_R2 2 RCDDLTR 7 1 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 ; 101.6 0.0092176 0.0 9659.0 7576.7 10641.0 19432.1 16021.0 14265.6 10281.6 14138.7 8062.8 14306.1 False True 12730.361080319157 10025.720104556058 10499.893387294109 14952.329567952209 13796.760692589904 13373.569776851473 11196.642481901587 11953.888790004252 8488.983147467567 13805.24779343794 0.9221392669511003 0.7262252916113242 0.7605726129946782 1.0830902705751875 0.9993852264751039 0.9687308751682344 0.8110424853962922 0.865894547411623 0.6149098715564266 1.0 13.752929162959367 -10.437269139904933 4.137060773335791 1.000004117126355 0.8667915492786143 0.08852863780597531 0.13244459008072007 98009024.1273258 271532770.23028743 6922.8760196442245 0.03498157536412883 3.653682962995859e-11 10.437269139904933 -0.1332125678477406 RCDDLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RCDDLTR 7 1 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 ; 113.41 0.001925 0.0 12375.4 5255.4 10420.400000000001 10077.1 14670.3 13578.6 10857.0 12818.3 12250.0 9984.2 False True 14470.310794708503 5777.121380271376 10668.86185558707 9512.512757399007 11795.760026629721 12866.51431224085 9828.546362126912 12481.833207111507 12429.13307527686 11794.256425116284 1.2268947081643458 0.4898249768394719 0.9045811343280068 0.80653772603602 1.0001274859100262 1.0909135640667567 0.8333332774753546 1.0582975947963116 1.0538293070183369 1.0 13.525796845552629 -6.268726662172117 22.69726931092594 1.004602439005558 0.8341372618548538 0.13785739300582456 0.17907089032465404 278.3557700859865 866976.8185637246 0.05225199473977176 0.060616938130126516 5.386086673270824e-07 6.268726662172117 -0.17046517715070408 RCDDLTR ddPTM_PC-9_Lapatinib_30min_R1 1 RCDDLTR 7 1 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 89.296 0.018701 0.0 5105.6 4372.6 5510.7 4891.2 4868.1 3909.4 3370.0 2650.3 3576.4 3646.2 False True 5032.793207747631 4362.475513351743 5057.631517917157 5250.915164564886 4581.767929052846 3742.204075256507 3544.482110463359 2773.4426133958314 3173.588170838406 4276.440811743895 1.1768649279388252 1.0201182958902602 1.18267310143238 1.2278704174146184 1.0713974846724095 0.8750744462497235 0.828839276982288 0.6485399273572188 0.7421096913403191 1.0 12.062194857116847 -6.817485964156489 2.2501732928686273 0.7778275237038896 1.146560497608115 0.7295797253535306 0.09754783038528245 0.15093059437871986 1.5667916331440355 0.03873997784431055 0.03446370180993199 1.522348332441024e-07 6.817485964156489 0.3687329739042253 RCDELTR ddPTM_PC-9_AZD4547_30min_R2 2 RCDELTR 7 1 P17844-2;P17844;J3KTA4;J3QSF1 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 ; 113.41 0.0057117 9518300.0 14675.400000000001 12683.900000000001 15659.5 21628.1 20112.0 15166.2 13941.400000000001 17297.1 17002.9 18029.1 False True 19341.871932717237 16783.72262781668 15451.84479826447 16642.075695814015 17319.795958390114 14217.855116481951 15182.157591929543 14624.230642815994 17901.63858189168 17397.906696630936 1.1117355823308757 0.9646978179890349 0.88814390533872 0.956556210238598 0.9955103369846242 0.8172164251941416 0.8726427757466668 0.8405741505469702 1.0289535916041146 1.0 14.086626112056537 -4.787496230621968 2.9353226481047368 0.9172542029604787 1.1435003882168557 0.40165607430121075 0.06769161923294982 0.37968395600071847 4.705781248181892 0.017391359361941607 0.20517718586964034 1.631187066750601e-05 4.787496230621968 0.22624618525637707 RCDELTR ddPTM_PC-9_Lapatinib_30min_R1 2 RCDELTR 7 1 P17844-2;P17844;J3KTA4;J3QSF1 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 ; 134.48 0.0025486999999999997 10370500.0 17225.3 22102.5 21525.1 19241.1 18802.0 21475.6 16130.0 18227.9 19128.8 17987.6 False True 16979.664063266846 22051.32301922355 19755.389367288833 20656.154680427997 17696.103326154265 20557.13865006871 16965.13247530385 19074.834778220516 16974.31310880598 21096.732693029582 0.8048480449712943 1.0452482543189907 0.9364193808938039 0.9791162916546241 0.8388077710251837 0.9744228620226508 0.8041592374590392 0.9041606136727937 0.8045944059581482 1.0 14.364731961772991 -6.254088517931857 24.937058861926776 0.8830588689466751 0.9484688242503809 0.088572714899115 0.08239266965349558 1155.3628975887152 3919449.812340971 0.022973788106031727 0.029045193968084942 5.57072194866073e-07 6.254088517931857 0.06540995530370586 RCPT(ph)PEIQK ddPTM_PC-9_AZD4547_30min_R2 1 RCPTPEIQK 9 1 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 RCPT(1)PEIQK 94.363 0.023981 0.0 12538.0 11033.0 16797.0 17369.0 16401.0 18546.0 19196.0 20255.0 11790.0 12928.0 True False 16524.82319339907 14599.201487925744 16574.26080503516 13364.845398374957 14124.004251867353 17386.315688193095 20904.406812420526 17125.055163596102 12413.19533023796 12475.394654976955 1.3245932213300065 1.1702396510639856 1.3285560307643651 1.071296401276024 1.1321488932803179 1.3936485513311572 1.6756509425600326 1.3727064864247964 0.9950142399131092 1.0 13.60679783501356 -6.764597048416457 24.998104067041815 1.3349636312163866 1.202810814864549 0.013432809148353542 0.2006727160903136 224.774455992108 1779441.8234034618 0.07101359021435935 0.06528184363981422 1.719503054303933e-07 6.764597048416457 -0.1321528163518375 RCPT(ph)PEIQK ddPTM_PC-9_Lapatinib_30min_R1 2 RCPTPEIQK 9 1 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 RCPT(1)PEIQK;RCPT(1)PEIQK 85.67200000000001 0.010403 26850000.0 116229.0 166416.0 176840.0 163697.0 173870.0 160285.0 172521.0 177639.0 158776.0 130048.0 True False 114571.55314621207 166030.67397656894 162300.89782214028 175735.8234571839 163643.30844157224 153429.98419258438 181453.29322826405 185892.75644305273 140892.97489459766 152526.6235219324 0.751157735618119 1.0885356939190012 1.0640824144304382 1.1521649099634999 1.072883570506898 1.0059226425511352 1.1896499708601507 1.2187561236895963 0.9237270952525748 1.0 17.21870156151016 -4.761433223055484 11.494591702302834 1.0891203607380733 0.7505457150526634 0.5652664897686094 0.08602093514539869 0.04449473443688861 248.8514767225969 0.020840071927629794 0.11686657386785163 1.7320753334815377e-05 4.761433223055484 -0.33857464568540985 RCRT(ph)WKT(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RCRTWKTK 8 3 I3L3T1 I3L3T1 YWHAE 2 RCRT(1)WKT(1)K 66.92 0.032754000000000005 0.0 31616.0 29372.0 32126.0 31058.0 42972.0 36565.0 36522.0 30392.0 32051.0 25755.0 True False 36967.96435553629 32287.85804721448 32892.005678533475 29317.920951394568 34551.945077083095 34647.46703099634 33062.37176361785 29594.2422029858 32519.685240465216 30424.177623532174 1.2150850817720278 1.061256558739021 1.0811140430988186 0.9636388964781105 1.1356739204138164 1.1388135929168905 1.0867137371050948 0.972721188036174 1.0688763930733902 1.0 14.89293064644945 -4.761255212672526 7.843855962479836 1.0594030493874025 1.2171878232631879 0.4013325533356098 0.05800306295395974 0.10520382118862019 53.341411408068325 0.014903664074156301 0.08789302374050213 1.7327854290598842e-05 4.761255212672526 0.15778477387578538 RCS(ph)DNTEVEVSNLENK ddPTM_PC-9_AZD4547_30min_R2 1 RCSDNTEVEVSNLENK 16 1 Q9NQW6;Q9NQW6-2;C9JJT6 Q9NQW6 ANLN Actin-binding protein anillin 1 RCS(0.812)DNT(0.188)EVEVSNLENK 152.13 1.4347999999999999e-05 9102200.0 23175.0 24266.0 24542.0 23542.0 21828.0 30290.0 29185.0 31253.0 23772.0 27127.0 True False 30544.167930054522 32109.509952506687 24216.55704454207 18114.75562027424 18797.558978706227 28395.9615116666 31782.40846116341 26423.566972494125 25028.53938850013 26177.29198681619 1.1668192395698396 1.2266169460415604 0.9250978694334916 0.6920026574711193 0.7180864616620138 1.0847555020575774 1.2141213261161679 1.0094079626648151 0.9561164463117646 1.0 14.676028239274808 -5.26255418646344 24.823405874633558 0.947040659450283 1.1967181071253632 0.3099082145194748 0.1472440107057788 117.13168398600583 2608250.03851865 0.04426732999899528 0.10136216645509805 5.463183820622803e-06 5.26255418646344 0.24967744767508016 RCS(ph)DNTEVEVSNLENK ddPTM_PC-9_Lapatinib_30min_R1 1 RCSDNTEVEVSNLENK 16 1 Q9NQW6;Q9NQW6-2;C9JJT6 Q9NQW6 ANLN Actin-binding protein anillin 1 RCS(0.997)DNT(0.003)EVEVSNLENK 216.9 1.9809999999999998e-22 6873900.0 23206.0 51893.0 46676.0 38729.0 51107.0 46047.0 52608.0 49293.0 49380.0 42803.0 True False 22875.0781845408 51772.84494679643 42838.479454570435 41577.25985615665 48100.98674022792 44077.67715079973 55331.78482707908 51583.332732943694 43818.304405547606 50201.44151858758 0.4556657636229644 1.0313019582839473 0.8533316605800865 0.8282084856221162 0.9581594728194818 0.8780161648242618 1.1021951392888178 1.0275269229837645 0.872849525432919 1.0 15.615441170854158 -4.755413725428744 24.999980875731826 0.9469439421572021 0.45566496335526463 0.7489146453345203 0.08588132039617144 103.8041537986187 430633.41208315856 0.022312821463573246 0.19841177945373392 1.756249746535919e-05 4.755413725428744 -0.4912789788019375 RCS(ph)DPSLNEK ddPTM_PC-9_AZD4547_30min_R2 2 RCSDPSLNEK 10 1 G5E953;Q13615-3;Q13615-2;Q13615 G5E953 MTMR3 Myotubularin-related protein 3 1 RCS(1)DPSLNEK;RCS(0.988)DPS(0.012)LNEK 71.806 0.032701999999999995 7324000.0 54487.0 41532.0 59754.0 81360.0 58963.0 66282.0 51635.0 62462.0 52017.0 53633.0 True False 71812.73259999476 54956.40679747412 58961.62291743001 62603.708999469534 50777.00522546519 62137.376061944015 56230.41496975067 52809.93313396887 54766.512425189794 51755.324994614675 1.387542878099348 1.0618502888966985 1.1392378064202122 1.2096090403448083 0.9810972152285531 1.2005987030012781 1.0864662713566506 1.0203768045020283 1.0581812099699586 1.0 15.659419685602955 -4.758018798723135 24.972299736805397 1.090926171643001 1.3875432978672853 0.5967779352676134 0.07462736018746693 67.57226613329843 493239.61210397485 0.018207504893963618 0.1288137600639697 1.7457465854924754e-05 4.758018798723135 0.29661712622428427 RCS(ph)DPSLNEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RCSDPSLNEK 10 1 G5E953;Q13615-3;Q13615-2;Q13615 G5E953 MTMR3 Myotubularin-related protein 3 1 RCS(1)DPSLNEK;RCS(1)DPSLNEK 93.62299999999999 0.009806200000000001 13393700.0 44667.0 44789.0 47311.0 52389.0 56935.0 42626.0 44664.0 48691.0 45313.0 36595.0 True False 52228.24088653652 49235.355919811045 48439.07366796669 49453.81417742964 45778.995461317274 40390.61752121564 40433.10258064254 47412.91284237896 45975.61690122617 43229.383814139386 1.2081652866274213 1.138932632754928 1.1205127021061847 1.143986099594933 1.0589786719639516 0.9343324830830633 0.9353152650632451 1.0967751251377131 1.0635270004979471 1.0 15.399724651947482 -6.377592349539387 3.3651781344343252 1.0068156583076917 1.1504766173305225 0.6424425749200091 0.05150549707642621 0.1830660897609828 3.86555708243871 0.01849560495628657 0.021287212335572167 4.1918685019456595e-07 6.377592349539387 0.14366095902283083 RCS(ph)DPSLNEK ddPTM_PC-9_Lapatinib_30min_R1 2 RCSDPSLNEK 10 1 G5E953;Q13615-3;Q13615-2;Q13615 G5E953 MTMR3 Myotubularin-related protein 3 1 RCS(1)DPSLNEK;RCS(1)DPSLNEK 86.756 0.0050714 25397000.0 68408.0 74648.0 82916.0 77353.0 73934.0 73205.0 66109.0 67802.0 87753.0 62748.0 True False 67432.48937550926 74475.15714235941 76098.96654501575 83041.79766204358 69585.34747983671 70074.1927991898 69531.80054617877 70952.32844337012 77869.33305994367 73593.90819354559 0.9162781408233909 1.011974482269595 1.0340389362782865 1.1283786892204564 0.9455313515465612 0.9521738214377846 0.9448037514642675 0.9641059998712347 1.058094820228246 1.0 16.16729873030599 RCS(ph)GLLDAPR ddPTM_PC-9_AZD4547_30min_R2 2 RCSGLLDAPR 10 1 Q6P0Q8;Q6P0Q8-2;A0A669KBJ4;E7ERL6 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 RCS(1)GLLDAPR;RCS(1)GLLDAPR 86.46700000000001 0.005156 7153800.0 26496.0 31382.0 32763.0 40609.0 46002.0 36107.0 27711.0 51672.0 38577.0 36679.0 True False 34921.176848963274 41525.61779154224 32328.54121303607 31247.22245279571 39615.41635232012 33849.22358209791 30177.225316679793 43687.279704435314 40616.1014634936 35394.879374218726 0.986616636823447 1.1732097559227475 0.9133677465386096 0.8828175997558526 1.11924145675082 0.9563310902749776 0.8525873191323992 1.2342824859648114 1.1475134873062447 1.0 15.111253038282154 -7.7717570395557845 24.999953130840378 1.1431734628864296 0.9883647019246463 0.2675759141980276 0.10786300098480343 277.8357675459694 673191.8342812788 0.058559511041285206 0.028619651529676552 1.691386891588648e-08 7.7717570395557845 -0.1548087609617833 RCS(ph)GLLDAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RCSGLLDAPR 10 1 Q6P0Q8;Q6P0Q8-2;A0A669KBJ4;E7ERL6 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 RCS(1)GLLDAPR 68.83 0.018322 4191100.0 16109.0 14216.0 16595.0 19789.0 14871.0 13987.0 12105.0 15112.0 10744.0 10174.0 True False 18835.935532747146 15627.270529729027 16990.68773688797 18680.286486803623 11957.134302366723 13253.497097293743 10958.326767389355 14715.32601248753 10901.110674348958 12018.465662660314 1.5672496025235363 1.300271679294368 1.413715212389852 1.554298777492093 0.9948969059765974 1.1027611568147586 0.9117908287940064 1.2243930652650599 0.9070301468029467 1.0 13.552965105701427 -6.267579172483804 24.95083778362819 1.0330780533986463 1.4443280545787034 0.7859930871382199 0.1111307682789158 217.4764606303258 883777.5746857363 0.032542141229998454 0.03784074701419772 5.400336569089749e-07 6.267579172483804 0.41125000118005706 RCS(ph)GLLDAPR ddPTM_PC-9_Lapatinib_30min_R1 2 RCSGLLDAPR 10 1 Q6P0Q8;Q6P0Q8-2;A0A669KBJ4;E7ERL6 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 RCS(1)GLLDAPR;RCS(1)GLLDAPR 73.219 0.013077000000000002 5320900.0 28296.0 37634.0 38704.0 35855.0 37519.0 33289.0 27209.0 28284.0 38112.0 41534.0 True False 27892.49385114911 37546.86078522605 35521.9065217605 38491.896308773685 35312.20618519208 31865.30707044914 28617.74888534052 29598.17789581846 33819.425222847916 48713.096559423786 0.5725871648730811 0.7707754882595823 0.7292064974442405 0.7901755180317569 0.724901693369373 0.6541425062473193 0.5874754615615639 0.6076020615875332 0.694257347848797 1.0 15.572022073853484 -8.597307098848063 19.480883310821465 1.0000000004028917 0.6834105061989516 0.6424415125890415 0.07137161981187495 5451.140553478049 1426780.6413036773 0.07521805116958663 0.019421217333415074 2.527510108338126e-09 8.597307098848063 -0.3165894942039401 RCS(ph)LGIFLPR ddPTM_PC-9_AZD4547_30min_R2 2 RCSLGIFLPR 10 1 Q8NG31-2;Q8NG31;Q8NG31-4;H0YCZ2;E9PPJ1;Q8NG31-3 Q8NG31-2 CASC5 Protein CASC5 1 RCS(1)LGIFLPR;RCS(1)LGIFLPR 67.118 0.020367 3492400.0 13549.400000000001 10934.0 13587.2 14582.8 13048.1 10970.8 11484.1 15313.7 11960.1 12659.0 True False 17857.827354972193 14468.201673976258 13407.02485028124 11220.960762014072 11236.596541600542 10284.794141703265 12506.162652350416 12947.319538818147 12592.286468971923 12215.812263099717 1.4618616404997726 1.1843831062859675 1.0975139893709578 0.9185603478787251 0.9198403102135836 0.8419247054713279 1.023768406307926 1.0598820004731158 1.0308185978765751 1.0 13.576462175122305 -4.799787665635644 1.3103725674193067 0.9702643499692232 1.6598599412987507 0.8369322425847666 0.06647225513202457 0.5507379556500803 0.8499725357805576 0.022258424081780134 0.5084503810717496 1.5856682646371222e-05 4.799787665635644 0.6895955913295275 RCS(ph)LGIFLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RCSLGIFLPR 10 1 Q8NG31-2;Q8NG31;Q8NG31-4;H0YCZ2;E9PPJ1;Q8NG31-3 Q8NG31-2 CASC5 Protein CASC5 1 RCS(1)LGIFLPR 75.89 0.033343 0.0 6437.3 5617.3 6044.0 5273.9 8138.6 6174.7 6283.8 7159.4 3753.7 3473.4 True False 7527.0077475295375 6174.948420557604 6188.111881997639 4978.420481214494 6543.899753428942 5850.887862061892 5688.552973227693 6971.473336011332 3808.590761197288 4103.099924580726 1.8344685447305265 1.5049471214592924 1.508155296176456 1.2133315231710358 1.5948672646810151 1.4259676755641681 1.3864037137260252 1.699074715252934 0.9282227660069643 1.0 12.00249857390147 -10.470642306767465 0.07196064020047102 7.759997414185824e-12 2.220505775232109 0.4457356335304453 0.20473599098953632 101.86776186459376 1.4583986093800898 32.54010781569195 14.31835870710732 3.3834338755820514e-11 10.470642306767465 2.220505775224349 RCS(ph)LGIFLPR ddPTM_PC-9_Lapatinib_30min_R1 1 RCSLGIFLPR 10 1 Q8NG31-2;Q8NG31;Q8NG31-4;H0YCZ2;E9PPJ1;Q8NG31-3 Q8NG31-2 CASC5 Protein CASC5 1 RCS(1)LGIFLPR 69.846 0.017108 2019000.0 7859.3 5059.9 6187.7 4887.1 3724.0 5344.1 5425.5 5301.4 4389.1 4168.9 True False 7747.224940780894 5048.184112429332 5678.971191212734 5246.513636887686 3504.9616416657 5115.545300705557 5706.405842824617 5547.722397712206 3894.7533387280064 4889.488810289928 1.5844652153568408 1.0324564199442343 1.1614652188714167 1.0730188452106484 0.7168360083552108 1.0462331542593764 1.1670761636299254 1.134622168689092 0.7965563456309582 1.0 12.255467925829333 -2.602555764605163 1.3223591165221158 1.007606248126131 199.9981493672322 0.5853832558673742 0.1429711791316646 374.5064467077752 2.5117912793899837 0.04269232950208364 224155.3693185225 0.002497147727935854 2.602555764605163 198.99054311910606 RDAEDDGEEEDD ddPTM_PC-9_Lapatinib_30min_R1 1 RDAEDDGEEEDD 12 1 H0YCE2;Q5TB25;Q5TB19;Q9BTT0-3;Q9BTT0-2;Q9BTT0 H0YCE2 ANP32E Acidic leucine-rich nuclear phosphoprotein 32 family member E 0 93.667 0.017305 0.0 2330.2 2223.2 1156.1 1922.7 2132.2 1173.1 2218.2 684.42 2376.8 2196.0 False True 2296.9709206936554 2218.052316993 1061.0499206750555 2064.101771939176 2006.7881880664886 1122.929247629664 2333.047542264042 716.2206517980509 2109.099755186422 2575.575674013931 0.8918281624837366 0.8611870112658173 0.4119661213531544 0.8014137548994461 0.7791610273050102 0.4359915567456901 0.9058353694683261 0.27808177372705567 0.8188847939767482 1.0 11.330679213743192 -8.526113999684522 24.870577494970604 1.000000030905527 0.668403619059695 0.19448003554141413 0.21107898962730046 503.09504767307726 3867484.4592236504 0.19501993845537935 0.05035393165209821 2.9777346894199568e-09 8.526113999684522 -0.331596411845832 RDDDYRGGGDRYEDR ddPTM_PC-9_Lapatinib_30min_R1 1 RDDDYRGGGDRYEDR 15 3 E7EX17;P23588-2;P23588;F8VX11;F8VP89 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 50.108000000000004 0.032048 7387300.0 19727.0 0.0 4371.4 2140.7 988.87 1372.5 895.58 1481.8 2231.1 0.0 False True 19445.689362511268 0.0 4012.0003660919765 2298.134219165858 930.7066107932222 1313.8013744537666 941.9487502934048 1550.6498375768551 1979.8100234754406 0.0 0.0 RDDGLSAAAR ddPTM_PC-9_AZD4547_30min_R2 1 RDDGLSAAAR 10 1 F8WBN3;B9A031;C9JQZ0;B8ZZY7;F8WBV6;P84101-4;P84101;P84101-3;P84101-2 F8WBN3 SERF2 Small EDRK-rich factor 2 0 141.89 7.9614e-05 4101200.0 8222.9 7279.1 13695.0 17636.0 14467.0 11522.0 10400.0 16498.0 12605.0 11183.0 False True 10837.611153054811 9631.92672444125 13513.395351845953 13570.292673483844 12458.506768597344 10801.527518567933 11325.579852530393 13948.613186324783 13271.27456638247 10791.486573840286 1.0042741636102608 0.8925486455026564 1.2522274164343459 1.2574998431059239 1.1544754917082596 1.0009304505601655 1.0494920949987379 1.2925571552058184 1.2297911391145548 1.0 13.39760599553215 -5.255303917691215 24.983305050513007 1.159495565404321 0.9484113918926961 0.38191790700454187 0.10478544666699736 516.7226753673389 2104053.966568073 0.02850838251962766 0.07147871955372911 5.55515373588395e-06 5.255303917691215 -0.211084173511625 RDDGLSAAAR ddPTM_PC-9_Lapatinib_30min_R1 1 RDDGLSAAAR 10 1 F8WBN3;B9A031;C9JQZ0;B8ZZY7;F8WBV6;P84101-4;P84101;P84101-3;P84101-2 F8WBN3 SERF2 Small EDRK-rich factor 2 0 152.69 7.7396e-09 0.0 16159.0 17695.0 18191.0 16311.0 16431.0 13854.0 14692.0 18524.0 13933.0 13137.0 False True 15928.569696802322 17654.028314677562 16695.40619929066 17510.565351900925 15464.560884588911 13261.496715251362 15452.679871491893 19384.692665186718 12363.718819005564 15407.712946047819 1.0338049360458852 1.1457916159585475 1.0835745874648544 1.13648050253899 1.0036895766905933 0.8607050742500382 1.0029184685359556 1.2581161612411154 0.802436991284741 1.0 13.9113651099118 -6.306583498589459 8.583844510972593 0.9950940385974832 1.1019762709096317 0.18326620821659623 0.11515530376569127 0.7084296210660184 128.01746643313018 0.03571581182381105 0.04065906310980067 4.936469992660866e-07 6.306583498589459 0.10688223231214844 RDDGTGQLLLPLSDAR ddPTM_PC-9_AZD4547_30min_R2 2 RDDGTGQLLLPLSDAR 16 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 97.904 0.001344 5913200.0 18772.8 18551.1 28925.0 40272.0 37003.0 31748.0 26789.0 36507.0 24863.0 26985.0 False True 24742.15990150279 24547.38028846726 28541.43560074074 30987.91259619763 31865.772168273143 29762.79254118162 29173.16910283047 30865.68199740324 26177.207421179504 26040.263363594746 0.950150140804384 0.9426702005934935 1.0960501897474173 1.1899999690294947 1.223711593210024 1.1429528236949826 1.1203100635155496 1.1853060610959338 1.0052589351986436 1.0 14.668456419121766 -5.328940202691036 3.8286788770603124 1.136716838227573 0.9438252991535656 0.4911980696115291 0.07027992149550921 0.16282245942055049 4.671444929958573 0.01836044305593303 0.043605648132628815 4.68877936750213e-06 5.328940202691036 -0.19289153907400736 RDDGTGQLLLPLSDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RDDGTGQLLLPLSDAR 16 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 135.47 4.9148e-06 1846600.0 11817.0 10502.0 11770.0 11364.0 15297.0 11200.0 13302.0 10137.0 10264.0 10025.0 False True 13817.384703611211 11544.569154699935 12050.641437973569 10727.311922585091 12299.662660433303 10612.652283526839 12041.938261859823 9870.914491039319 10414.091582419731 11842.453142143664 1.1667670994989519 0.9748460911039073 1.0175798285482782 0.9058352854620867 1.038607669610494 0.8961532003668783 1.0168449152655925 0.8335194045152484 0.879386344824044 1.0 13.531680343068443 -1.522878745404539 0.7498197970689339 0.9340070234003761 39.355279751077745 0.4980269113723239 0.0653693309463952 313.2521583838836 1.353930195583665 0.023884028655233567 20328.630343350113 0.029999999991420473 1.522878745404539 38.42127272767737 RDDGTGQLLLPLSDAR ddPTM_PC-9_Lapatinib_30min_R1 2 RDDGTGQLLLPLSDAR 16 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 98.507 0.0012916 6830600.0 31626.0 27672.0 29544.0 22865.0 29244.0 29603.0 23398.0 22689.0 28393.0 22087.0 False True 31175.007440501893 27607.9271841626 27115.00636313799 24546.568375404004 27523.925415916143 28336.948697963464 24609.43395270674 23743.21377026675 25195.081348455118 25904.708520922442 1.2034494584381366 1.0657493853622988 1.046721152690756 0.9475716878102871 1.0625066633614468 1.0938918179711066 0.9499984889940163 0.9165597733358042 0.9726062475517074 1.0 14.660926730063306 -1.522878745281145 0.6383785520409007 0.9857061354797461 18.298029371082656 0.6060138378233197 0.051328566957709404 156.887029488023 1.0578942469647543 0.024169622219714616 3827.9686845007013 0.029999999999944228 1.522878745281145 17.31232323560291 RDEDMLYS(ph)PELAQR ddPTM_PC-9_AZD4547_30min_R2 1 RDEDMLYSPELAQR 14 1 Q9Y2W2 Q9Y2W2 WBP11 WW domain-binding protein 11 1 RDEDMLYS(1)PELAQR 83.891 0.0028046 7193700.0 12109.0 19298.0 28410.0 31214.0 25589.0 22545.0 16060.0 38561.0 19456.0 18971.0 True False 15959.410117153393 25535.701107041685 28033.264837235747 24018.09455149267 22036.409048291793 21135.25758601928 17489.308887657528 32602.28349362768 20484.404439788766 18306.831064322985 0.8717734959741705 1.3948728219165458 1.5313007881450322 1.3119744464294536 1.2037260283259588 1.1545011537910805 0.9553433265542787 1.780880775000114 1.1189486792014767 1.0 14.160094459955253 -6.253868038604761 22.223066353820432 1.2265462603815553 1.3039956028851345 0.010277599731004394 0.26386652453950976 776.7813330208475 2279954.516886164 0.0794640581662902 0.10019083375204468 5.573550768504484e-07 6.253868038604761 0.07744934250357915 RDEDMLYS(ph)PELAQR ddPTM_PC-9_Lapatinib_30min_R1 3 RDEDMLYSPELAQR 14 1 Q9Y2W2 Q9Y2W2 WBP11 WW domain-binding protein 11 1 RDEDMLYS(1)PELAQR;RDEDMLYS(1)PELAQR;RDEDMLY(0.079)S(0.921)PELAQR 146.67 9.040799999999999e-05 9437900.0 23100.4 26065.8 39739.7 26156.4 38477.8 34781.4 34736.8 33218.1 38466.9 31192.8 True False 22770.984059905455 26005.446241577978 36472.455265678116 28080.02891119255 36214.61145426542 33293.88060140346 36535.30153553222 34761.534194636064 34134.352647585234 36584.433918206596 0.6224227525514138 0.7108336375989712 0.9969391721960538 0.7675403417194396 0.9898912618200405 0.9100559182039015 0.9986570139971491 0.9501728049791321 0.933029406000948 1.0 15.158942315329277 -4.176705644835481 0.7002828307003052 0.9585398380982723 1.1044799848680742e-15 0.7055180847266318 0.07072277626214335 3.306974471132602 0.670016046818267 0.02745328130453246 3.049538699863458 6.657242164292161e-05 4.176705644835481 -0.9585398380982711 RDEFEFLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RDEFEFLEK 9 1 A0A3B3IUA7;Q14258 A0A3B3IUA7 TRIM25 E3 ubiquitin/ISG15 ligase TRIM25 0 118.03 0.00046821 0.0 10371.0 11122.0 9776.9 9033.7 12240.0 10590.0 10829.0 10519.0 10018.0 8856.3 False True 12126.60546341305 12226.118657262683 10010.018375099731 8527.571076650564 9841.659865575195 10034.641757370462 9803.198724829348 10242.887395801778 10164.494297806008 10461.877083567773 1.1591232975256445 1.1686352802276718 0.9568090214730427 0.8151090868812272 0.9407164495397543 0.9591626509483313 0.9370401359644154 0.9790678397369094 0.9715746243827642 1.0 13.352854104575822 -5.277432445290807 5.936244877927223 0.9389967174207121 1.1653143119569827 0.7739410140834335 0.04729036926015511 0.06734768482458581 9.673014547893724 0.012993076978991849 0.02976141650221342 5.2791931849134e-06 5.277432445290807 0.22631759453627054 RDGEAQEAASETQPLS(ph)SPPTAASSK ddPTM_PC-9_AZD4547_30min_R2 1 RDGEAQEAASETQPLSSPPTAASSK 25 1 A0A087WWW8;Q9Y6J0-2;Q9Y6J0;B5MEB3 A0A087WWW8 CABIN1 Calcineurin-binding protein cabin-1 1 RDGEAQEAASETQPLS(0.499)S(0.499)PPT(0.001)AAS(0.001)SK 110.07 1.3565999999999999e-07 8519000.0 7515.7 6987.7 8351.0 15843.0 12591.0 9013.6 7091.8 10589.0 8351.9 9599.2 True False 9905.536263728616 9246.337373078826 8240.260283553527 12190.64112190998 10842.95698648021 8449.978167103276 7722.956461362992 8952.713361013033 8793.36438325822 9263.134929769089 1.0693503159384015 0.9981866229070808 0.8895757587500607 1.3160383838016563 1.1705493948527104 0.9122158136709682 0.833730321313101 0.9664884975648527 0.9492860084547448 1.0 13.17728481316127 -6.778643891448828 24.814283450710334 0.9240862416571038 1.0852723432104345 0.3303165002348525 0.11097780416330864 288.5217199987249 416135.6973573185 0.042256167002668876 0.03735703620810499 1.664777158594284e-07 6.778643891448828 0.16118610155333069 RDGEAQEAASETQPLS(ph)SPPTAASSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RDGEAQEAASETQPLSSPPTAASSK 25 1 A0A087WWW8;Q9Y6J0-2;Q9Y6J0;B5MEB3 A0A087WWW8 CABIN1 Calcineurin-binding protein cabin-1 1 RDGEAQEAASETQPLS(0.57)S(0.427)PPT(0.002)AASSK 68.291 0.0063445 0.0 5769.0 7334.9 8845.7 6015.7 7645.7 7581.3 10443.0 6331.7 7956.2 5683.6 True False 6745.577757056201 8063.060397334658 9056.615035504063 5678.6598321625415 6147.579970116687 7183.723281884106 9453.763439227348 6165.499583990695 8072.544373348392 6713.991688647156 1.004704514076545 1.200933925933908 1.3489166289583145 0.8457948855916398 0.9156371135388465 1.0699630882819278 1.4080689815587553 0.9183061090790567 1.2023464948576634 1.0 12.712955035764432 -8.207965558230523 0.006658815374887059 3.137993453991529e-05 2.1681713549224373 0.007441174916971938 0.1805443594384606 23810.87290782634 142.7215547009368 23322.216160237476 23132.270742057593 6.194902018642426e-09 8.207965558230523 2.1681399749878976 RDGEAQEAASETQPLSS(ph)PPTAASSK ddPTM_PC-9_Lapatinib_30min_R1 1 RDGEAQEAASETQPLSSPPTAASSK 25 1 A0A087WWW8;Q9Y6J0-2;Q9Y6J0;B5MEB3 A0A087WWW8 CABIN1 Calcineurin-binding protein cabin-1 1 RDGEAQEAASETQPLS(0.282)S(0.705)PPT(0.01)AAS(0.002)S(0.001)K 86.191 4.3672e-06 13750000.0 23609.0 13699.0 19920.0 12131.0 21286.0 19151.0 15202.0 15193.0 20130.0 10350.0 True False 23272.331330639656 13667.280807164047 18282.25449342366 13023.154207829695 20033.99932988615 18331.956373161458 15989.085176042721 15898.922244773363 17862.747421702592 12138.983709491884 1.9171564842320554 1.1258999216282937 1.5060778505805346 1.072837275302252 1.6503852224647837 1.510172252626641 1.3171683526966358 1.3097408008169131 1.4715191855587633 1.0 13.567360022012043 -12.820736951978127 0.2750246962439017 1.266988395064025e-11 1.4495501275013871 0.24024294300754778 0.23297532209288155 115.74318960276423 2.613610878243698 66.5750964041715 0.2690920008297767 1.5109950723487946e-13 12.820736951978127 1.4495501274887173 RDGS(ph)YGSGR ddPTM_PC-9_Lapatinib_30min_R1 1 RDGSYGSGR 9 1 Q08170;A0A0D9SEM4;A0A0D9SGD2 Q08170 SRSF4 Serine/arginine-rich splicing factor 4 1 RDGS(0.998)Y(0.001)GS(0.001)GR 60.08 0.032787000000000004 1027100.0 1154.6 3417.1 1007.2 2066.5 2965.1 2071.8 2718.7 3720.4 1243.3 1188.5 True False 1138.1351922722918 3409.1879148959997 924.3919039044338 2218.4773036419147 2790.6986476108923 1983.1939436016867 2859.4609832987335 3893.2633659879425 1103.266461470582 1393.9306414232958 0.8164934168533523 2.445737121765967 0.6631548776060825 1.591526319685965 2.002035513590119 1.4227350232983715 2.0513653250200696 2.7930108215518255 0.7914787355159032 1.0 10.444943062680428 -5.996934391477061 24.995741197584596 1.7746613749388085 1.3730479595745122 0.04032813086874609 0.6942811650288175 284.5617010984048 2320139.3060621377 0.18776380780983143 0.2768671740156906 1.007083796711041e-06 5.996934391477061 -0.4016134153642963 RDHALLEEQSK ddPTM_PC-9_AZD4547_30min_R2 2 RDHALLEEQSK 11 1 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ; 126.5 0.00025792 19279200.0 80400.0 68695.0 114482.0 141051.0 126307.0 112618.0 95449.0 109494.0 110200.0 110863.0 False True 105965.5275761112 90899.31534605811 112963.89387879016 108533.87116622642 108771.45326752112 105575.97865701135 103943.77609078621 92574.21822181143 116024.94702224102 106981.720114071 0.9905012507101563 0.849671469566345 1.0559177190116271 1.014508563243332 1.0167293361103356 0.9868599845323037 0.971603148462695 0.8653274421378032 1.0845305805377548 1.0 16.707004779906626 -5.265593103410548 24.999787030236984 0.9943378124356065 0.9200863624570581 0.19784992596508133 0.06324563076417587 548.0146828522285 3298325.260645956 0.01620206074066667 0.035821576074270924 5.425089365960158e-06 5.265593103410548 -0.07425144997854838 RDHALLEEQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RDHALLEEQSK 11 1 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ; 109.15 0.0013271 11839300.0 81316.0 64795.0 83043.0 99517.0 107423.0 109088.0 96696.0 101769.0 96746.0 84459.0 False True 95081.19273579147 71227.419384763 85023.06006233135 93941.38512846707 86374.23429245802 103367.23324155145 87536.25486158469 99097.67158316869 98160.72722454972 99770.748122924 0.9529966901585755 0.7139108478670143 0.8521842490103158 0.941572423740125 0.8657270384104907 1.0360474907354245 0.8773739448533991 0.993253768740653 0.9838627961735775 1.0 16.60632927202638 -6.098518695530557 1.1967491655900102 0.9693202792256318 0.8261230353580364 0.3560320592869275 0.0729641607347269 0.49799489419683046 1.45669750582537 0.02754065733676447 0.04778055740946683 7.970421787402375e-07 6.098518695530557 -0.14319724386759536 RDHALLEEQSK ddPTM_PC-9_Lapatinib_30min_R1 2 RDHALLEEQSK 11 1 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ; 121.21 0.00050021 18597100.0 123314.0 114640.0 133142.0 105079.0 126892.0 106723.0 101190.0 113288.0 117927.0 101694.0 False True 121555.5197469818 114374.55812346033 122195.57870298272 112806.86019326822 119428.46203927063 102158.70607346405 106429.12307352731 118551.77405817684 104644.81943363733 119271.67240126271 1.0191482797192244 0.9589415141147083 1.0245146751349574 0.9457975890013088 1.001314558896101 0.8565211170157325 0.892325234741997 0.9939642135589084 0.8773652395984134 1.0 16.863891911107686 -6.72506990834595 24.999986276447853 0.9216759420066424 0.9876891269150482 0.31460258818219 0.04852123323089674 210.62672285061862 144782.0586145312 0.015427750756988396 0.015427288753064077 1.883345903058087e-07 6.72506990834595 0.0660131849084058 RDHRPPCAQEAPR ddPTM_PC-9_Lapatinib_30min_R1 1 RDHRPPCAQEAPR 13 2 Q13501;Q13501-2;E7EMC7;E9PFW8;E3W990;C9JRJ8 Q13501 SQSTM1 Sequestosome-1 0 37.55 0.045151 707340.0 529.88 1188.8 0.0 436.85 1175.4 622.69 791.9 699.02 0.0 651.54 False True 522.3238140319089 1186.0474066396541 0.0 468.97740628887993 1106.2652829253116 596.059000261287 832.900707203541 731.4990210979709 0.0 764.1578208775209 0.6835287158771708 1.55209745190811 0.0 0.613717995780413 1.4476921556006996 0.7800208071898059 1.0899590169044913 0.9572617083967729 0.0 1.0 9.5777268174123 RDHVFEDSYR ddPTM_PC-9_AZD4547_30min_R2 2 RDHVFEDSYR 10 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 0 ; 117.02 0.00039347 19696900.0 17110.2 15577.400000000001 28230.0 50723.0 22817.0 19970.0 21589.3 28638.0 21911.9 27543.0 False True 22550.887685731115 20612.48991734021 27855.651754845687 39029.59601253803 19649.253400088866 18721.272743082944 23510.705875984087 24212.65513577214 23070.11829996954 26578.727953436734 0.8484562438517753 0.7755258247667542 1.048043074282787 1.468452368409578 0.7392849437532296 0.7043705317982387 0.8845685134808742 0.9109787036531727 0.8679918143707281 1.0 14.697984439047538 RDHVFEDSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RDHVFEDSYR 10 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 0 123.51 0.0001781 8017700.0 4470.2 6357.8 9345.2 6600.2 10901.0 6743.5 8162.3 8060.9 8627.9 4725.7 False True 5226.916569525503 6988.960366763589 9568.025009868366 6230.412192137111 8765.027303483266 6389.858988746715 7389.107854065436 7849.3099162295375 8754.066715116836 5582.43200137938 0.9363153135110233 1.2519562020704713 1.7139528090094378 1.1160748918388292 1.570109103221945 1.1446371379298172 1.3236359802035456 1.406073538251792 1.5681456958103148 1.0 12.446678057602764 -11.645545562801773 2.517645514353634 0.30390936015551273 1.3417394581391775 0.16683456491108928 0.2255272645969094 17868037.167846937 5083668.846917634 71196723.76664501 0.055823694305840985 2.2618012367144464e-12 11.645545562801773 1.0378300979836648 RDHVFEDSYR ddPTM_PC-9_Lapatinib_30min_R1 2 RDHVFEDSYR 10 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 0 ; 105.4 0.00097862 13811600.0 17164.0 15719.400000000001 18646.0 13228.8 19342.4 16828.2 14551.6 15678.400000000001 19566.4 12655.6 False True 16919.23821250789 15683.002695097053 17112.997855641457 14201.690081983144 18204.71806062154 16108.497114450189 15305.010646474377 16406.875700813183 17362.6259886737 14843.103597473004 1.1398720019301316 1.0565851401702162 1.1529258516092886 0.9567871024224975 1.2264765209697008 1.0852512756963182 1.031119303720282 1.1053534453270546 1.1697436371480716 1.0 13.85750516130181 -11.250964554822172 6.641742809996875 0.9984428450409819 1.0996129846145895 0.15153015753447197 0.07256510143304323 0.0016093530711273998 6.588710267375039e-05 0.06758047319593768 0.016147451198969258 5.610937681335742e-12 11.250964554822172 0.10117013957360754 RDIEDLR ddPTM_PC-9_AZD4547_30min_R2 1 RDIEDLR 7 1 H7BZW2;Q6P2H3-3;Q6P2H3-4;Q6P2H3-2;Q6P2H3 H7BZW2 CEP85 Centrosomal protein of 85 kDa 0 77.318 0.018963999999999998 11829000.0 31708.0 33393.0 40698.0 63407.0 45809.0 35603.0 34111.0 51457.0 34347.0 44793.0 False True 41790.48443262861 44186.63421429386 40158.317928399214 48789.49577838456 39449.21107089762 33376.73878177174 37146.81291823697 43505.50301422683 36162.512299209775 43224.8107039281 0.9668170606662913 1.022251653499511 0.9290571149858103 1.12873821733014 0.9126520261964416 0.7721662220891714 0.8593863642961242 1.006493777664438 0.8366147060054901 1.0 15.399572025381097 -6.499509985164059 24.816614533748304 0.8874823096710824 1.0083307116081093 0.31918863319677404 0.08136221595349027 817.469643235649 868118.5602120848 0.02503217279173346 0.028196227386197256 3.165847674407424e-07 6.499509985164059 0.12084840193702684 RDIEDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RDIEDLR 7 1 H7BZW2;Q6P2H3-3;Q6P2H3-4;Q6P2H3-2;Q6P2H3 H7BZW2 CEP85 Centrosomal protein of 85 kDa 0 68.383 0.031173000000000003 8835200.0 29587.0 27368.0 38702.0 35927.0 38974.0 38183.0 36920.0 31359.0 29535.0 24433.0 False True 34595.49473011297 30084.914171189084 39624.80245815234 33914.12666690556 31337.324477199963 36180.616262670104 33422.670322347396 30535.85947760699 29966.89350026958 28862.509488478423 1.1986308655497573 1.0423526818830022 1.3728814008348824 1.1750234913025732 1.08574496925534 1.2535506060937973 1.1579959925414434 1.0579765938161596 1.0382636171061983 1.0 14.816909121831335 -7.788021748685849 2.900649016547836 1.025588339794746 1.1862286043716805 0.41138061026191797 0.084477830401622 0.2759342899518538 4.676626605511229 0.05269188526506407 0.023534601519373182 1.6292144424703823e-08 7.788021748685849 0.16064026457693448 RDLFAFQES(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 1 RDLFAFQESPPR 12 1 E7EX48;P51957-3;P51957-2;P51957 E7EX48 NEK4 Serine/threonine-protein kinase Nek4 1 RDLFAFQES(1)PPR 74.89 0.039146 0.0 11231.0 8139.6 11202.0 7719.5 10586.0 11138.0 8493.0 8895.9 9811.7 7223.6 True False 11070.843880486838 8120.75325629553 10281.014800970475 8287.217781497106 9963.352292876772 10661.653703946124 8932.725983431845 9309.235990079598 8706.60302421854 8472.189635158025 1.3067275825065197 0.9585188252392157 1.2135014965087842 0.9781671726405509 1.1760067611719522 1.258429539832563 1.0543585977304708 1.0987992940394045 1.0276685720168188 1.0 13.048519166560817 -8.118687263813936 1.4705625665624378 1.0033265009013954 1.1333604973194138 0.17677044934944464 0.10664443204973018 0.75061018461755 2.9388915123380808 0.09360172323492144 0.029904189450003647 7.608739863491742e-09 8.118687263813936 0.13003399641801838 RDLNES(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 2 RDLNESPVK 9 1 Q96RL1-2;Q96RL1-3;Q96RL1;Q96RL1-4 Q96RL1-2 UIMC1 BRCA1-A complex subunit RAP80 1 RDLNES(1)PVK;RDLNES(1)PVK 98.40700000000001 0.0020500999999999996 14664200.0 112115.0 103534.0 151709.0 197262.0 163133.0 153494.0 115561.0 168263.0 116105.0 135199.0 True False 147765.23786313104 136999.34078228092 149697.2395351005 151786.2935675191 140484.79883055162 143895.99591521116 125845.70512867924 142261.819649083 122242.07326694473 130465.72416137274 1.1325981503031446 1.0500791810485548 1.1474066502703832 1.163418932774826 1.0767946886707678 1.1029409972632087 0.9645882544063527 1.0904152838880479 0.9369669624164566 1.0 16.9933113074579 -7.1838133015349115 6.489828482084197 1.0057452896719996 1.1123555277892918 0.5739583620492429 0.048040580183652974 0.18870749169339193 13.029340325576362 0.017999690160167458 0.01387678478181381 6.549176555232431e-08 7.1838133015349115 0.1066102381172922 RDLNES(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RDLNESPVK 9 1 Q96RL1-2;Q96RL1-3;Q96RL1;Q96RL1-4 Q96RL1-2 UIMC1 BRCA1-A complex subunit RAP80 1 RDLNES(1)PVK 81.709 0.007718399999999999 5177100.0 44184.0 45738.0 41620.0 58022.0 51061.0 45342.0 45901.0 45037.0 37073.0 35445.0 True False 51663.478526221355 50278.56636808849 42612.37864472895 54771.21544986202 41055.96359445545 42964.18569997089 41552.92498553812 43854.8264706459 37615.122489774636 41870.897917534385 1.2338755817459102 1.200799812488215 1.0177087371915197 1.3080974656367552 0.9805369752355451 1.0261109227843588 0.9924058726272716 1.0473820398363298 0.898359585310504 1.0 15.353660236421163 -6.287096860276993 24.920426882273112 0.9950142308664343 1.1785681015044736 0.614161854771619 0.07713594009180393 512.1445878700353 497430.86223738507 0.023131179762914362 0.026237219232150322 5.163012062730276e-07 6.287096860276993 0.1835538706380393 RDLNES(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 1 RDLNESPVK 9 1 Q96RL1-2;Q96RL1-3;Q96RL1;Q96RL1-4 Q96RL1-2 UIMC1 BRCA1-A complex subunit RAP80 1 RDLNES(1)PVK 70.54 0.017143000000000002 12770000.0 97171.0 74056.0 92267.0 65901.0 70066.0 86640.0 72910.0 77168.0 83782.0 65870.0 True False 95785.32372102106 73884.5278819872 84681.16342091962 70747.57937929129 65944.85563505601 82934.60916770449 76684.92304863008 80753.5069956342 74345.58889642743 77255.5417337422 1.2398505216770201 0.9563654104792503 1.0961176573296127 0.915760575767104 0.8535938543066857 1.0735101625917651 0.9926138802174382 1.0452778555866917 0.9623334097203824 1.0 16.2373508044115 -4.756802785560608 24.92985536982295 0.9894872551468576 1.2398509130422812 0.5455221040850635 0.06884752591121811 108.55714687471736 583612.3779608858 0.017409729920665775 0.13600460565187386 1.750641479749835e-05 4.756802785560608 0.2503636578954236 RDLSMPRCAKAK ddPTM_PC-9_AZD4547_30min_R2 1 RDLSMPRCAKAK 12 3 Q92994-8 Q92994-8 BRF1 Transcription factor IIIB 90 kDa subunit 0 72.607 0.020531 0.0 9047.8 11403.0 14108.0 16476.0 16245.0 8902.9 10302.0 14878.0 12089.0 16370.0 False True 11924.812194068923 15088.796752181384 13920.918701996561 12677.712751662488 13989.662159111349 8346.200255603062 11218.858042381557 12578.946962428185 12727.999859817353 15796.891282640216 0.754883475533793 0.9551750709814036 0.8812441924756911 0.8025447871249511 0.8855959004089053 0.5283444765347602 0.710194040185006 0.7962925576535208 0.8057281418277924 1.0 13.947353053623281 RDPHLACVAYER ddPTM_PC-9_AZD4547_30min_R2 2 RDPHLACVAYER 12 1 A0A087WVQ6;Q00610-2;Q00610;A0A087WX41;P53675-2;P53675 A0A087WVQ6 CLTC;CLTCL1 Clathrin heavy chain;Clathrin heavy chain 1;Clathrin heavy chain 2 0 ; 88.101 0.0032609 13194000.0 37367.0 35476.0 47853.0 70944.0 54378.0 51676.0 40342.0 49358.0 39775.0 45849.0 False True 49248.92871811638 46942.923229008746 47218.437953405264 54588.95687387374 46828.553332604315 48444.69155090407 43932.35984719051 41730.85523400522 41877.42529772812 44243.84046534948 1.1131250858904698 1.0610047124135418 1.067231900684241 1.2338204889023199 1.058419722159497 1.0949477043893732 0.9929599100149792 0.9432014670310468 0.9465142459892317 1.0 15.433188999747708 -7.304571903857705 2.3826678108114554 0.9578099344882985 1.10794682958979 0.6424572435632909 0.04935891704037471 0.19563106483755247 2.178043999620087 0.024630312698482357 0.0156982590674703 4.9593881061270855e-08 7.304571903857705 0.15013689510149153 RDPHLACVAYER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RDPHLACVAYER 12 1 A0A087WVQ6;Q00610-2;Q00610;A0A087WX41;P53675-2;P53675 A0A087WVQ6 CLTC;CLTCL1 Clathrin heavy chain;Clathrin heavy chain 1;Clathrin heavy chain 2 0 ; 77.279 0.0070384 8469200.0 33284.0 29865.0 31870.0 44936.0 39647.0 42842.0 39466.0 44531.0 38037.0 30149.0 False True 38918.32381103461 32829.799829090996 32629.90166764808 42418.38160447765 31878.454958370887 40595.29010096935 35727.494770903635 43362.10843449462 38593.21916606581 35614.7750406473 1.0927578165695826 0.9218028133442427 0.9161900259206307 1.191033259540889 0.8950907291141912 1.139844069059478 1.003164971002279 1.2175314426387716 1.0836294521590886 1.0 15.12018825713826 -6.792864461855598 24.996190815143404 1.0970753884514646 1.0044248233796462 0.14698826258558417 0.1019576453110919 366.43766279689896 291469.9937219415 0.0348252518343752 0.0307157231599503 1.611148376977562e-07 6.792864461855598 -0.09265056507181835 RDPHLACVAYER ddPTM_PC-9_Lapatinib_30min_R1 2 RDPHLACVAYER 12 1 A0A087WVQ6;Q00610-2;Q00610;A0A087WX41;P53675-2;P53675 A0A087WVQ6 CLTC;CLTCL1 Clathrin heavy chain;Clathrin heavy chain 1;Clathrin heavy chain 2 0 ; 75.73899999999999 0.007704399999999999 12168100.0 66931.0 71988.0 73770.0 65015.0 72927.0 78795.0 68315.0 55665.0 79680.0 52385.0 False True 65976.55166635793 71821.31620892952 67704.91536043494 69796.41998368221 68637.57723999847 75425.1215301163 71852.01643213785 58251.399115073335 70705.59933240247 61439.677451375086 1.0738427414202076 1.168972872062532 1.1019738086030533 1.1360154037091237 1.117153931908578 1.2276288655618293 1.1694725527978782 0.9481071765257063 1.1508133223577008 1.0 15.906883021706776 -7.737729992211858 24.999994219688944 1.0370951088773177 1.1437279167695724 0.39673021344809933 0.06161105905134449 219.9537082717155 231927.17041734862 0.027858402985022585 0.016072698670061558 1.8292371285101088e-08 7.737729992211858 0.10663280789225471 RDPSSNDINGGMEPTPSTVSTPS(ph)PSADLLGLR ddPTM_PC-9_AZD4547_30min_R2 5 RDPSSNDINGGMEPTPSTVSTPSPSADLLGLR 32 1 O95782-2;O95782 O95782-2 AP2A1 AP-2 complex subunit alpha-1 1 RDPS(0.001)S(0.001)NDINGGMEPT(0.008)PS(0.029)T(0.029)VS(0.07)T(0.07)PS(0.605)PS(0.188)ADLLGLR;RDPSSNDINGGMEPTPSTVS(0.087)T(0.087)PS(0.622)PS(0.202)ADLLGLR;RDPSSNDINGGMEPTPSTVST(0.002)PS(0.499)PS(0.499)ADLLGLR;RDPSSNDINGGMEPTPSTVS(0.002)T(0.007)PS(0.887)PS(0.103)ADLLGLR;RDPSSNDINGGMEPTPSTVS(0.003)T(0.03)PS(0.719)PS(0.248)ADLLGLR 152.61 4.6768e-16 59161800.0 33379.2 32853.4 44630.7 61926.1 57960.0 50268.3 39254.7 54850.9 47195.6 47184.3 True False 43993.09126950921 43472.619066746985 44038.86775681866 47649.99439370763 49913.254462424964 47125.01525443749 42748.292253569714 46374.953753290196 49690.26306427295 45532.39201878319 0.966193281727018 0.9547624699535553 0.9671986426421785 1.0465076021934205 1.0962141949808955 1.0349778073376268 0.9388545243995754 1.0185046666153499 1.0913167716682783 1.0 15.47460563207563 -5.730707056176515 8.78546415279911 1.0319814098021658 0.9616749421035912 0.36321751346054687 0.042238344010721046 0.31803955723273347 81.76195716572055 0.012496639896946764 0.021388716033636433 1.8590580191002751e-06 5.730707056176515 -0.07030646769857463 RDPSSNDINGGMEPTPSTVSTPS(ph)PSADLLGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RDPSSNDINGGMEPTPSTVSTPSPSADLLGLR 32 1 O95782-2;O95782 O95782-2 AP2A1 AP-2 complex subunit alpha-1 1 RDPSSNDINGGMEPTPS(0.001)T(0.001)VS(0.032)T(0.023)PS(0.727)PS(0.216)ADLLGLR;RDPSSNDINGGMEPTPS(0.006)T(0.006)VS(0.006)T(0.013)PS(0.485)PS(0.485)ADLLGLR;RDPSSNDINGGMEPT(0.003)PS(0.034)T(0.034)VS(0.034)T(0.034)PS(0.671)PS(0.188)ADLLGLR 99.171 2.1013e-13 38739300.0 48580.0 53941.0 50136.0 49052.0 68278.0 49177.0 54267.0 42288.7 38093.5 37814.3 True False 56803.6345012637 59295.90599635017 51331.4323818388 46303.775468729684 54899.416037724084 46598.07154883922 49126.43690094328 41178.666433581384 38650.5453716783 44669.73325216588 1.2716358564444636 1.3274291489859102 1.1491322791668992 1.0365805232670506 1.2290070264760804 1.0431687891617272 1.0997700976546867 0.9218471532194513 0.8652513135346351 1.0 15.447010019081452 -5.978901283451511 0.39421369189877253 0.9205595072926578 1.3894985251992042 0.6745898047939689 0.08148044105679472 1.4355350089628405 0.3431263345110778 0.08220583179309651 0.2926161191525335 1.0497810201757863e-06 5.978901283451511 0.46893901790654646 RDPSSNDINGGMEPTPSTVSTPS(ph)PSADLLGLR ddPTM_PC-9_Lapatinib_30min_R1 6 RDPSSNDINGGMEPTPSTVSTPSPSADLLGLR 32 1 O95782-2;O95782 O95782-2 AP2A1 AP-2 complex subunit alpha-1 1 RDPSSNDINGGMEPTPS(0.002)T(0.002)VS(0.083)T(0.265)PS(0.455)PS(0.192)ADLLGLR;RDPSSNDINGGMEPTPS(0.002)T(0.002)VS(0.027)T(0.027)PS(0.471)PS(0.471)ADLLGLR;RDPSSNDINGGMEPTPSTVS(0.001)T(0.001)PS(0.499)PS(0.499)ADLLGLR;RDPSSNDINGGMEPTPS(0.009)T(0.009)VS(0.007)T(0.007)PS(0.784)PS(0.184)ADLLGLR;RDPSSNDINGGMEPTPSTVS(0.045)T(0.045)PS(0.546)PS(0.365)ADLLGLR;RDPSSNDINGGMEPTPSTVS(0.017)T(0.017)PS(0.728)PS(0.239)ADLLGLR 130.26 3.1861e-16 53517700.0 59072.7 69226.4 84683.5 61764.3 80464.2 75394.9 61018.0 67788.4 75806.79999999999 51427.2 True False 58230.312465393574 69066.11052405747 77721.14951776323 66306.6526616648 75731.45395470377 72170.435881096 64177.21347663305 70938.09653772096 67268.63990300655 60316.32299756336 0.965415489066632 1.145065002169439 1.2885591437810788 1.0993152328656282 1.2555714637605337 1.1965324193255533 1.0640107070058906 1.1761011449684475 1.1152642694370485 1.0 15.880260861291426 -8.648051917418845 3.770331848070992 1.0000094411949068 1.153879300544892 0.2029067851855484 0.08801492781257367 1.0561480916360617 28.853014563761338 0.08461291547749686 0.022216593320349254 2.2487857603039572e-09 8.648051917418845 0.1538698593499852 RDQALTEEHAR ddPTM_PC-9_AZD4547_30min_R2 4 RDQALTEEHAR 11 1 P12814-4;P12814-3;P12814;P12814-2;H9KV75;H0YJ11 P12814-4 ACTN1 Alpha-actinin-1 0 ;;; 117.25 0.00046849 116611000.0 84762.7 76181.4 115975.6 158969.0 144397.9 106034.0 103297.0 128940.0 102211.4 122879.0 False True 111715.47542631412 100805.54774152678 114437.6877668891 122321.15309656697 124350.7440741854 99403.6772178298 112490.2328871952 109015.28574643694 107614.08593529114 118577.04361145683 0.9421340929393879 0.8501270116991433 0.9650914231077372 1.0315753317090492 1.0486915534987307 0.8383045671432602 0.9486678825944896 0.9193624872589079 0.9075456990470416 1.0 16.855465207140213 -5.301666572527533 0.0031833018215947848 1.8762254137348615 1.6913187418567555e-08 0.020642226789481577 0.06575031960649035 462526.0938906464 274.3971169549807 79308.63605529991 82436.86541770812 4.992676506615633e-06 5.301666572527533 -1.876225396821674 RDQALTEEHAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RDQALTEEHAR 11 1 P12814-4;P12814-3;P12814;P12814-2;H9KV75;H0YJ11 P12814-4 ACTN1 Alpha-actinin-1 0 ;; 126.12 0.00027007 46703200.0 56279.8 54447.5 70672.5 68726.1 67732.8 62572.0 69763.6 71345.8 56559.6 42200.0 False True 65806.85856328157 59852.687969008264 72357.60042694885 64875.59943002249 54461.04406397312 59290.61416828938 63155.08676327507 69473.04834712375 57386.67714974937 49850.525944983776 1.3200835360474947 1.2006430591136212 1.4514912140907883 1.3014025067984387 1.0924868500701 1.1893678761528796 1.2668890762150538 1.3936271890851435 1.1511749587774194 1.0 15.605321105320707 -13.700605350683993 0.2500924572543265 4.9446364979938295e-11 1.289750137988199 0.3901110425247848 0.10197095799658633 132.7584365819983 1.918228319041682 67.64834199464495 0.1571137827201711 1.9924831131458656e-14 13.700605350683993 1.2897501379387526 RDQALTEEHAR ddPTM_PC-9_Lapatinib_30min_R1 4 RDQALTEEHAR 11 1 P12814-4;P12814-3;P12814;P12814-2;H9KV75;H0YJ11 P12814-4 ACTN1 Alpha-actinin-1 0 ;;; 126.71 0.00015754 88838500.0 85826.2 67087.4 87173.4 66415.1 78982.7 82931.9 62828.2 69263.3 82128.3 60746.8 False True 84602.30264940261 66932.06324713766 80006.33955105499 71299.48800827864 74337.0928719627 79385.09596070113 66081.13677525635 72481.52577610806 72878.14600466055 71246.80343997708 1.1874540128761997 0.9394395259223883 1.122946373565482 1.0007394657129556 1.0433744292063443 1.1142267740837 0.9274961624197973 1.0173302137992926 1.0228970632494103 1.0 16.120537667191456 -7.255075590545007 24.987709604566923 0.9933750444183732 1.0605018856620199 0.22285444653170272 0.06874069651428068 852.4698221897779 3347266.455014463 0.025108087081160836 0.018943829801431653 5.558075085186274e-08 7.255075590545007 0.06712684124364665 RDS(ph)ALQQLR ddPTM_PC-9_AZD4547_30min_R2 2 RDSALQQLR 9 1 H7BZW2;Q6P2H3-3;Q6P2H3-4;Q6P2H3-2;Q6P2H3 H7BZW2 CEP85 Centrosomal protein of 85 kDa 1 RDS(1)ALQQLR;RDS(1)ALQQLR 85.973 0.0055111000000000005 4303000.0 12874.599999999999 13830.400000000001 28636.0 30602.0 33401.5 24546.6 17531.3 26124.8 24489.5 21529.3 True False 16968.454991684124 18300.806331787197 28256.267929569993 23547.181696186904 28764.278276857956 23011.697221600378 19091.55173737175 22087.812448181456 25783.964973694867 20775.56576000892 0.8167505611012943 0.8808812497907801 1.3600721278050942 1.1334074830112733 1.384524426873928 1.1076327589545507 0.9189425673365417 1.0631629820978685 1.2410716161254516 1.0 14.34260014453763 -5.1074197558592385 7.071132912618017 1.1508226829056727 0.8325564785553057 0.43336518155502624 0.1390399410489652 0.22254161677683085 12.571282861502876 0.037060570261699025 0.1003066452833495 7.808727078493302e-06 5.1074197558592385 -0.318266204350367 RDS(ph)ALQQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RDSALQQLR 9 1 H7BZW2;Q6P2H3-3;Q6P2H3-4;Q6P2H3-2;Q6P2H3 H7BZW2 CEP85 Centrosomal protein of 85 kDa 1 RDS(1)ALQQLR;RDS(1)ALQQLR;RDS(1)ALQQLR 81.676 0.0077402 6133600.0 24186.899999999998 22309.7 30403.699999999997 26870.6 31393.4 30483.7 28404.2 28529.399999999998 27904.0 20218.3 True False 28281.264456949673 24524.45957632918 31128.639514674327 25365.127397660603 25242.088629407528 28885.08110851315 25713.548547400304 27780.533479397967 28312.043210818436 23883.717742025266 1.1841232073843588 1.0268275584741349 1.3033414584322045 1.0620259237542689 1.0568743485438241 1.2094047258684353 1.076614153003295 1.1631578374633003 1.1854118992957778 1.0 14.54373980369466 -11.842156829603091 2.352411386127383 0.22044887505939864 1.1382820397776658 0.21262053716316143 0.08118603836020165 5589265.213153054 1277809.5431355236 23013330.338676415 0.019572681305770046 1.4382791024570185e-12 11.842156829603091 0.9178331647182671 RDS(ph)ALQQLR ddPTM_PC-9_Lapatinib_30min_R1 2 RDSALQQLR 9 1 H7BZW2;Q6P2H3-3;Q6P2H3-4;Q6P2H3-2;Q6P2H3 H7BZW2 CEP85 Centrosomal protein of 85 kDa 1 RDS(1)ALQQLR;RDS(1)ALQQLR 78.324 0.011879 2020600.0 14204.3 16416.6 18299.1 16341.7 20855.1 19040.7 16311.8 17422.6 21301.9 15281.3 True False 14001.744077250401 16378.588371332893 16794.618634568713 17543.523132313123 19628.44402070416 18226.373647039596 17156.34518974962 18232.117600328325 18902.655703048506 17922.65234394767 0.7812316954292021 0.9138484671251131 0.9370610059420204 0.9788463669127312 1.095175180772422 1.0169462252161852 0.9572436523628254 1.017266710888646 1.0546795943085832 1.0 14.129496534819163 -4.5309677475203145 0.8620060244029415 1.0204379378357882 0.560390672676136 0.7932368553741095 0.03750106261799837 1.5674637799061344 0.6763112897341673 0.014268504711483004 0.7565245185531113 2.944640306679064e-05 4.5309677475203145 -0.4600472651596522 RDS(ph)APTENR ddPTM_PC-9_AZD4547_30min_R2 2 RDSAPTENR 9 1 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 RDS(0.99)APT(0.01)ENR;RDS(0.995)APT(0.005)ENR 92.906 0.0030563 17776100.0 19623.3 21960.0 26598.0 38621.0 33177.2 22189.8 24357.0 31453.0 27892.0 30303.0 True False 25863.101210003813 29058.140548794458 26245.293141175516 29717.52513850188 28571.11846015813 20802.268298170344 26524.725814238733 26592.661568036943 29366.31417735344 29242.101193515336 0.8844474286867989 0.9937090483510921 0.8975173489583441 1.0162582005253429 0.9770542229877105 0.7113807643475157 0.9070731832403616 0.9093964004862302 1.0042477448188862 1.0 14.835759359531723 -8.262099082557507 23.580179846503864 1.002123894516118 0.9131167497660223 0.17049001493728722 0.07939983948088668 51.16878805737795 1828510.1092009055 0.06629192189249662 0.02106569852298595 5.468911776143944e-09 8.262099082557507 -0.08900714475009563 RDS(ph)APTENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RDSAPTENR 9 1 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 RDS(0.998)APT(0.002)ENR;RDS(0.949)APT(0.051)ENR 75.89 0.011604000000000001 15589200.0 23848.0 25897.0 18319.8 22017.1 26243.5 18753.7 19499.4 22025.8 15141.3 16748.5 True False 27884.995380529777 28467.88301268942 18756.613510228402 20783.55326740128 21101.27456554105 17770.22295799796 17652.275668569357 21447.64608826415 15362.712867974655 19784.870468946945 1.4094100552387374 1.4388713364270325 0.9480281177310497 1.0504770956181797 1.066535896641843 0.8981723173719512 0.8922108282829159 1.084042785214439 0.7764879174764867 1.0 14.272109999602565 -5.2609427067722745 24.999944618187023 0.9692608417176998 1.424140738814264 0.8100695085617026 0.08900270298622077 16.405855857040113 825729.2199230276 0.022552842058937463 0.05275990867719006 5.483492997775467e-06 5.2609427067722745 0.4548798970965642 RDS(ph)APTENR ddPTM_PC-9_Lapatinib_30min_R1 2 RDSAPTENR 9 1 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 RDS(0.999)APT(0.001)ENR;RDS(0.998)APT(0.002)ENR 96.23 0.0023709 19902500.0 22717.0 18353.800000000003 20059.9 14583.5 16678.2 12843.599999999999 19643.6 16523.699999999997 18060.2 18058.3 True False 22393.05141421242 18311.302903754113 18410.65245545329 15656.019239129853 15697.221066602811 12294.309167893922 20660.649491127017 17291.451424732542 16026.07009366284 21179.653093827757 1.0572907551889164 0.864570482936307 0.8692612845872618 0.7392009288241072 0.7411462783201744 0.5804773625625044 0.9754951792457833 0.8164180663455566 0.7566729267314207 1.0 14.370391338855475 -4.501426795533495 1.3372954160514166 0.793199078845798 1.334968166754123 0.2901174572490117 0.11534507545421792 3.085678193481889 3.031321872360666 0.033398115095508246 2.7193095597997687 3.151905619107738e-05 4.501426795533495 0.5417690879083251 RDS(ph)ASYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RDSASYR 7 1 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 1 RDS(0.947)AS(0.053)YR 84.81700000000001 0.028939999999999997 18193000.0 38582.0 77747.0 54274.0 29999.0 135090.0 149170.0 44438.0 105140.0 139130.0 160820.0 True False 45113.17057076483 85465.20834797701 55568.09799529123 28318.253288070235 108620.08425167925 141347.26260122296 40228.51093674084 102380.18640503856 141164.5130418996 189975.39294958021 0.23746849457886338 0.4498751497287842 0.2925015557674835 0.14906274359219748 0.5717587028784681 0.7440293208854515 0.21175642967306588 0.5389128813762235 0.7430673565147718 1.0 17.535453036315893 -9.320439597593824 0.22064137990317553 1.261983539644572 0.21267244407232908 0.5911029581416487 0.1686560723573066 5.4020599799989455 0.5250781762259552 1.5850437202826482 0.4976061803631928 4.781458628546859e-10 9.320439597593824 -1.049311095572243 RDS(ph)ASYR ddPTM_PC-9_Lapatinib_30min_R1 1 RDSASYR 7 1 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 1 RDS(0.921)AS(0.079)YR 84.81700000000001 0.028939999999999997 21492000.0 21209.0 43578.0 28110.0 33423.0 70825.0 38834.0 163100.0 146250.0 78066.0 109750.0 True False 20906.555770745737 43477.09781842436 25798.904307737925 35881.038915859535 66659.21274730748 37173.16034647546 171544.51994557088 153045.3089118743 69273.385008576 128720.14126731733 0.16241868261570974 0.3377645284597229 0.2004263206498546 0.27875232704526176 0.5178615567929972 0.2887905496411532 1.3326936892441623 1.1889771670933775 0.5381705172674858 1.0 16.97387828893544 -7.246873921942354 24.869975833690898 1.0307084313570545 0.30422025417594767 0.7378308560173741 0.20936001324167272 376.6382999495998 643096.7130046804 0.08089666588187222 0.062371871335129454 5.6640369525616917e-08 7.246873921942354 -0.7264881771811068 RDS(ph)DGVDGFEAEGK ddPTM_PC-9_AZD4547_30min_R2 2 RDSDGVDGFEAEGK 14 1 Q96KR1 Q96KR1 ZFR Zinc finger RNA-binding protein 1 RDS(1)DGVDGFEAEGK;RDS(1)DGVDGFEAEGK 139.12 3.5600000000000005e-05 9523100.0 78925.0 84900.0 98398.0 110825.0 102842.0 106657.0 98984.0 122969.0 103550.0 94795.0 True False 104021.50825801732 112342.26469001129 97093.17822788881 85276.00847918169 88564.16348213785 99987.72092934379 107793.38424258333 103966.966596507 109023.44159848522 91476.25590335249 1.1371421712746888 1.2281030042233516 1.0614030632219007 0.932220144310218 0.968165592344626 1.0930456208765686 1.1783755596257721 1.1365459328194558 1.191822298823335 1.0 16.481109697417452 -9.886462328819006 15.19842498176494 1.0000100012753053 1.0993626199994602 0.10447078038269053 0.08989211110394107 0.0 0.0 0.09863086826360691 0.023921499282190124 1.2987862170881256e-10 9.886462328819006 0.0993526187241549 RDS(ph)DGVDGFEAEGK ddPTM_PC-9_Lapatinib_30min_R1 3 RDSDGVDGFEAEGK 14 1 Q96KR1 Q96KR1 ZFR Zinc finger RNA-binding protein 1 RDS(1)DGVDGFEAEGK;RDS(1)DGVDGFEAEGK;RDS(1)DGVDGFEAEGK 161.2 0.00018194 20942200.0 67022.0 87045.0 104108.0 97187.0 114965.0 114651.0 125955.0 126742.0 125207.0 117094.0 True False 66066.25398967053 86843.4526505288 95548.64210850155 104334.45618632808 108202.98472988639 109747.6439945346 132476.3335974519 132630.89601441877 111104.86917183868 137333.54188205232 0.48106422571123186 0.6323542774795214 0.6957414831007754 0.7597157603051904 0.7878846146909657 0.7991321165283161 0.964632032218524 0.9657574850019351 0.8090148091225966 1.0 17.067324501939495 -4.347880363471123 0.3235736936313289 0.9710495475257237 5.175023891866503e-19 0.8711009772135356 0.05515793543505781 3.2451979074189796 0.22145071712293926 0.05753829940108082 1.3060278651553763 4.4886902432936284e-05 4.347880363471123 -0.9710495475257237 down RDS(ph)ELGPGVK ddPTM_PC-9_Lapatinib_30min_R1 1 RDSELGPGVK 10 1 A0A0A0MR62;K7EK60;O95466;O95466-2;O95466-3 A0A0A0MR62 FMNL1 Formin-like protein 1 1 RDS(1)ELGPGVK 58.595 0.034945 2960800.0 32845.0 35965.0 37992.0 33667.0 31680.0 31941.0 26703.0 27601.0 35523.0 28276.0 True False 32376.624276964674 35881.725252183 34868.444413361016 36142.98348981968 29816.644685276406 30574.957888107674 28085.550681217548 28883.443222404356 31522.025666226575 33163.46892459832 0.9762737532245905 1.0819653798510949 1.0514112529252955 1.0898432721859013 0.8990809964141153 0.921946915674715 0.8468821746323911 0.8709415558449213 0.9505044764133755 1.0 15.017307301297574 -6.26906962285639 24.59977993378157 0.905391942172747 1.0522755444339762 0.6428530373329925 0.04896915970762656 266.4178450886422 858925.3929965993 0.014724517661052027 0.01701676444610028 5.381834980306179e-07 6.26906962285639 0.1468836022612292 RDS(ph)FDDR ddPTM_PC-9_AZD4547_30min_R2 1 RDSFDDR 7 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 1 RDS(1)FDDR 61.593 0.032263 6861900.0 20473.0 17288.0 16336.0 23182.0 19229.0 21898.0 18273.0 20272.0 20519.0 17215.0 True False 26982.988135145908 22876.007914734015 16119.373966247218 17837.748058329693 16559.385266700643 20528.71459829896 19899.261600508464 17139.42820421723 21603.59244963127 16612.308089838196 1.6242768909186973 1.3770517492826506 0.9703271742297804 1.0737669902258256 0.9968142402096476 1.2357533033508115 1.1978625422123557 1.031730696994566 1.300457006503886 1.0 14.019964912719043 -5.0013615277855115 3.5374413735045143 1.1063855029433638 1.6053728556754971 0.7119870761388322 0.10697501064107526 0.1209339929105865 3.153944262825283 0.027589709155117836 0.12069065728955444 9.96869875503776e-06 5.0013615277855115 0.49898735273213335 RDS(ph)FDDRGPSLNPVLDYDHGSR ddPTM_PC-9_AZD4547_30min_R2 2 RDSFDDRGPSLNPVLDYDHGSR 22 2 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 1 RDS(0.5)FDDRGPS(0.5)LNPVLDYDHGSR;RDS(0.997)FDDRGPS(0.003)LNPVLDYDHGSR 97.62100000000001 0.00036407 9132600.0 8489.9 9496.2 27615.0 89084.0 48540.0 42040.0 23144.9 52461.0 24380.8 33087.0 True False 11189.511599109814 12565.660941687713 27248.807056679543 68547.06013408 41801.05886138905 39411.23215419163 25204.75126238758 44354.35788385163 25669.5193136103 31928.63420089898 0.3504538129850466 0.3935546025120584 0.8534285207825246 2.146883568610335 1.309202849027977 1.2343538375682217 0.7894090020824605 1.3891717887075419 0.8039654672384186 1.0 14.962563220157628 -5.522343535046065 24.999999460008098 1.2592849687303622 0.43487588183658893 0.4760387446426796 0.3622123297054089 15.880677092765598 741795.7162960684 0.1016568064395997 0.17872405602488226 3.0036993803502985e-06 5.522343535046065 -0.8244090868937732 RDS(ph)FDDRGPSLNPVLDYDHGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RDSFDDRGPSLNPVLDYDHGSR 22 2 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 1 RDS(0.598)FDDRGPS(0.402)LNPVLDYDHGSR 61.303999999999995 0.0020591 14367000.0 11552.0 11626.0 40375.0 38304.0 48585.0 48205.0 40525.0 39138.0 42827.0 25350.0 True False 13507.52543759979 12780.152446442718 41337.69312304016 36157.95106324355 39065.11802034075 45677.044939947424 36686.178624407556 38110.6689701388 43453.26385427614 29945.754329510404 0.45106646134102013 0.42677677462438685 1.3804191628695568 1.2074483302499834 1.3045294364765279 1.525326242823492 1.2250878111377117 1.2726568364511754 1.4510659299523672 1.0 14.870063853616863 -5.259040710569138 24.98414540634643 1.3083803656765034 0.43892151882158215 0.8629229192474055 0.13653705773380787 61.08405708551761 636231.7014837657 0.03341283915298537 0.08024644648786328 5.5075606635993865e-06 5.259040710569138 -0.8694588468549213 RDS(ph)FDDRGPSLNPVLDYDHGSR ddPTM_PC-9_Lapatinib_30min_R1 2 RDSFDDRGPSLNPVLDYDHGSR 22 2 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 1 RDS(0.668)FDDRGPS(0.332)LNPVLDYDHGSR;RDS(0.983)FDDRGPS(0.017)LNPVLDYDHGSR 93.06200000000001 6.0837e-05 43239500.0 33329.4 17956.2 113050.0 30980.6 70310.0 101174.0 47889.0 55307.2 147890.0 47225.0 True False 32854.1166441366 17914.623522125636 103755.46538561958 33259.016672251986 66174.50403477851 96847.0238681133 50368.45809732337 57876.9744208602 131233.0708492596 55387.77832664293 0.5931654534035161 0.3234400090300832 1.8732555903169448 0.6004757308753356 1.19474920341672 1.7485269637819616 0.9093785600188058 1.0449412518324444 2.369350690965215 1.0 15.757280050901088 -5.242291808661174 24.94612191118257 1.3114323584521694 0.4583025644445343 0.3311787907797852 0.5010981553739233 927.4210746909014 1208272.1176483445 0.1234273863613505 0.32544057894613115 5.724112904277735e-06 5.242291808661174 -0.8531297940076351 RDS(ph)FDNCSLGESSK ddPTM_PC-9_AZD4547_30min_R2 3 RDSFDNCSLGESSK 14 1 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 RDS(0.778)FDNCS(0.093)LGES(0.101)S(0.028)K;RDS(0.999)FDNCS(0.001)LGESSK;RDS(1)FDNCSLGESSK 180.93 5.6955e-05 29643700.0 72964.0 84179.0 115808.0 144121.0 137907.0 102788.0 84101.0 118838.0 85740.0 90294.0 True False 96165.03425451995 111388.21553993496 114272.31025239694 110896.13009725361 118760.99349809588 96360.65011096674 91585.82607477468 100474.31772557074 90272.04135832074 87132.83454335447 1.1036601157129962 1.2783724542383823 1.311472430011889 1.2727249225672246 1.3629878348443292 1.1059051460448106 1.0511057806710573 1.1531165978030702 1.0360278284462823 1.0 16.410928856196875 -6.882768462126429 6.501739724182774 1.073856001355857 1.2688804060335845 0.6520635236181331 0.07206785105633057 0.14063005688587127 7.460969776461466 0.0255195407143935 0.022513431551990818 1.3098800806527748e-07 6.882768462126429 0.19502440467772764 RDS(ph)FDNCSLGESSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RDSFDNCSLGESSK 14 1 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 RDS(0.641)FDNCS(0.32)LGES(0.029)S(0.011)K;RDS(1)FDNCSLGESSK;RDS(1)FDNCSLGESSK;RDS(0.947)FDNCS(0.052)LGES(0.001)SK 161.26 3.2371e-13 28597800.0 118282.2 125478.0 124015.2 136806.0 142558.0 149429.1 140553.9 141890.6 114142.7 95982.8 True False 138305.04028006087 137934.62658478742 126972.19269826492 129141.20335103621 114624.78326116553 141592.7749411037 127239.61706988575 138166.12209551779 115811.82105072672 113383.7218405732 1.2197962638281454 1.216529360173366 1.1198449886554105 1.138974812739163 1.010945675450109 1.2487927953202556 1.1222035668294172 1.2185710598721629 1.0214148836423593 1.0 16.790854006202025 -14.522878744862755 0.11402128777707986 0.5162295815985296 1.227732681938386 0.32843545379622874 0.07356597276273077 211.3406116115581 1.58041133681609 23.649491295991997 0.8355251123847578 3.000000002884558e-15 14.522878744862755 0.7115031003398564 RDS(ph)FDNCSLGESSK ddPTM_PC-9_Lapatinib_30min_R1 3 RDSFDNCSLGESSK 14 1 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 RDS(0.999)FDNCS(0.001)LGESSK;RDS(0.993)FDNCS(0.007)LGESSK;RDS(1)FDNCSLGESSK 161.48 0.00069196 43625000.0 124329.0 152792.0 187561.0 202591.0 146750.0 183988.0 157578.0 167813.0 196354.0 190035.0 True False 122556.0456608535 152438.21951151214 172140.45858639714 217490.2179637643 138118.45352160075 176119.26213697615 165736.61780492446 175610.20461147616 174238.54482071477 222882.2965442789 0.5498689109052046 0.6839404559043926 0.7723379615850237 0.975807506185475 0.619692347320019 0.7901895523675538 0.7436060215397071 0.7879055776715247 0.7817513886128666 1.0 17.765922502868968 -14.522878745280336 0.08070510282581882 1.747578618797605 0.523037172616345 0.40458235852084035 0.10215877072960751 292.18071727543213 1.6612782730343016 39.637466316629535 3.6047106868354413 3.0000000000000132e-15 14.522878745280336 -1.22454144618126 RDS(ph)FIGTPYWMAPEVVMCETSK ddPTM_PC-9_AZD4547_30min_R2 2 RDSFIGTPYWMAPEVVMCETSK 22 1 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 RDS(0.896)FIGT(0.055)PY(0.049)WMAPEVVMCETSK;RDS(0.613)FIGT(0.21)PY(0.176)WMAPEVVMCETSK 69.952 0.00062929 2889100.0 22553.7 20129.2 31019.0 51385.0 38234.6 37171.6 31733.6 37268.9 30699.1 36862.4 True False 29725.30745389732 26635.57025203977 30607.667792545435 39538.98214033609 32926.3857672366 34847.2539758028 34557.828923871035 31509.84785912349 32321.791752545207 35571.85859604134 0.835641111460095 0.7487820795229391 0.8604461223162415 1.1115242132649272 0.9256301769652501 0.9796298352451233 0.9714934863627521 0.885808307543146 0.9086337635487559 1.0 15.118448735372903 -5.531054331971386 24.99654787179261 0.9647189184515782 0.7953121974128872 0.5828981772787833 0.06144640877633878 121.48534752921637 371435.64563585 0.016777065532809003 0.029123158397939268 2.9440532979524506e-06 5.531054331971386 -0.16940672103869103 RDS(ph)FIGTPYWMAPEVVMCETSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RDSFIGTPYWMAPEVVMCETSK 22 1 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 RDS(0.858)FIGT(0.097)PY(0.045)WMAPEVVMCETSK;RDS(0.987)FIGT(0.013)PYWMAPEVVMCETSK;RDS(0.945)FIGT(0.05)PY(0.004)WMAPEVVMCETSK 85.399 8.5019e-05 25773600.0 76092.0 62676.0 64189.0 85836.0 100354.0 79674.0 90082.0 87483.0 78825.0 58795.0 True False 88972.87271449494 68898.05906874621 65719.50919813818 81026.8872040666 80690.35409721681 75495.75518193896 81548.78082279794 85186.66394590039 79977.66650275083 69454.06807903606 1.2810318412630233 0.9919945796456856 0.9462298036070674 1.1666255043817033 1.1617800991209657 1.0869882394221702 1.1741397311673458 1.2265179895432654 1.151518819772217 1.0 16.083771578083947 RDS(ph)FIGTPYWMAPEVVMCETSK ddPTM_PC-9_Lapatinib_30min_R1 3 RDSFIGTPYWMAPEVVMCETSK 22 1 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 RDS(0.572)FIGT(0.222)PY(0.205)WMAPEVVMCETSK;RDS(0.921)FIGT(0.067)PY(0.012)WMAPEVVMCETSK;RDS(0.523)FIGT(0.37)PY(0.107)WMAPEVVMCETSK 90.37 7.5822e-05 17967500.0 28789.3 28629.2 38972.4 29925.3 37100.7 35525.0 30482.9 29797.5 37597.5 24841.6 True False 28378.75930268899 28562.910846372797 35768.2397098145 32126.106389874356 34918.50976878265 34005.67856281974 32061.155408024795 31182.00063112186 33362.87363077313 29135.437460648656 0.9740289412512971 0.9803494759586454 1.2276541156495193 1.1026471263136173 1.19848929043694 1.1671586743377032 1.100417848584828 1.0702430905057583 1.145096025272804 1.0 14.830487352069945 -5.231415423841108 22.25987582550564 1.1312169269922763 0.9771888272841945 0.48259227776987845 0.06166897565635097 142.69823669376936 105794.65253560846 0.015134876907103774 0.04001913008049806 5.8692765901405455e-06 5.231415423841108 -0.15402809970808173 RDS(ph)FLGGGPGPEEPEDLALQLQQK ddPTM_PC-9_AZD4547_30min_R2 3 RDSFLGGGPGPEEPEDLALQLQQK 24 1 A0A2R8Y2X6;A1A5D9 A0A2R8Y2X6 CCDC64B Bicaudal D-related protein 2 1 RDS(1)FLGGGPGPEEPEDLALQLQQK;RDS(1)FLGGGPGPEEPEDLALQLQQK;RDS(1)FLGGGPGPEEPEDLALQLQQK 152.13 4.2565e-07 26438500.0 77755.0 74630.0 90150.0 117063.0 110488.0 89658.0 85333.0 117938.0 90114.0 97956.0 True False 102479.47259552914 98752.68803080735 88954.55209703636 90075.9339553209 95148.64836170476 84051.67108659631 92927.47168807454 99713.39204562802 94877.24206862281 94526.5902554859 1.0841338116454664 1.0447080315062585 0.941053219592609 0.9529163562534542 1.0065807737752686 0.8891854753188702 0.9830828705119979 1.0548713518188189 1.003709557408018 1.0 16.528432594953756 -11.020827156040113 11.359943635835611 1.0000000143788772 0.9927388947726342 0.0 0.05504544518179941 2.129660583332799e-08 9.661553504870591e-10 0.05665768368461425 0.013741479491893424 9.531754408611428e-12 11.020827156040113 -0.007261119606242983 RDS(ph)FLGGGPGPEEPEDLALQLQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RDSFLGGGPGPEEPEDLALQLQQK 24 1 A0A2R8Y2X6;A1A5D9 A0A2R8Y2X6 CCDC64B Bicaudal D-related protein 2 1 RDS(1)FLGGGPGPEEPEDLALQLQQK;RDS(1)FLGGGPGPEEPEDLALQLQQK;RDS(1)FLGGGPGPEEPEDLALQLQQK 101.53 6.428e-05 17099800.0 66487.8 64532.7 65559.5 78146.9 91806.0 78012.7 64330.4 64820.799999999996 61540.7 63987.3 True False 77742.8713460914 70939.07997424346 67122.68711578836 73768.58254866824 73817.27333488515 73921.57667849046 58236.5588002366 63119.32268331473 62440.61631393397 75587.69096681202 1.0285123192905263 0.9385004233743612 0.8880108157459082 0.9759338009287454 0.9765779638287376 0.9779578623581305 0.77045029495353 0.8350476364072065 0.8260685769770307 1.0 16.205863698295133 -7.242855869358456 24.701612498781042 0.8441455933795061 0.9607046688130951 0.3892783994049013 0.06425574949179742 649.4839914503897 863309.6279519112 0.023760565335772862 0.01836981188267869 5.716683265142856e-08 7.242855869358456 0.11655907543358901 RDS(ph)FLGGGPGPEEPEDLALQLQQK ddPTM_PC-9_Lapatinib_30min_R1 4 RDSFLGGGPGPEEPEDLALQLQQK 24 1 A0A2R8Y2X6;A1A5D9 A0A2R8Y2X6 CCDC64B Bicaudal D-related protein 2 1 RDS(1)FLGGGPGPEEPEDLALQLQQK;RDS(1)FLGGGPGPEEPEDLALQLQQK;RDS(1)FLGGGPGPEEPEDLALQLQQK;RDS(1)FLGGGPGPEEPEDLALQLQQK 147.17 5.461399999999999e-09 14087500.0 123748.0 106079.8 118127.0 111890.7 119461.6 120797.0 112453.6 109850.1 124178.0 120083.0 True False 121983.33082739616 105834.17874062354 108415.05404340637 120119.51533443318 112435.10355854218 115630.79390156038 118275.89716830931 114954.13667350625 110191.76598768911 140839.1865494606 0.8661178313789639 0.7514540614266908 0.7697790416116372 0.8528841885368956 0.7983225855898896 0.8210129349259808 0.8397939527062847 0.8162084678977898 0.7823942234215576 1.0 17.103689274142937 -11.263860682499894 2.8705687885569886 1.034273056568925 0.8100987379068888 0.7287600424914277 0.034609365711425484 35499181.96905071 31553930.83814618 8686604.0465216 0.008475111128619657 5.446773520850704e-12 11.263860682499894 -0.2241743186620363 RDS(ph)GDNSAPSGQER ddPTM_PC-9_AZD4547_30min_R2 2 RDSGDNSAPSGQER 14 1 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 RDS(0.989)GDNS(0.011)APSGQER;RDS(0.66)GDNS(0.337)APS(0.004)GQER 137.27 0.00010074 13461000.0 11009.0 11986.400000000001 13421.0 10547.099999999999 12357.7 16626.6 15491.5 17513.4 15804.5 11624.9 True False 14509.632998574758 15860.769393172583 13243.02877087438 8115.629046070614 10642.046664429072 15586.936073617571 16870.213488987945 14807.106447895532 16639.893604473767 11217.915789344172 1.2934339382684052 1.4138784504193398 1.1805248871144005 0.7234524842644655 0.9486652301792001 1.3894680942803568 1.5038634453837545 1.3199516493037602 1.4833320125544087 1.0 13.453517037698584 -6.783025227463372 24.930698720311973 1.369603899258861 1.1109844816677938 0.2071880470562597 0.21836294749767224 367.337923206533 424256.053110565 0.08326257951230452 0.0734964107211826 1.6480666552210142e-07 6.783025227463372 -0.2586194175910672 RDS(ph)GDNSAPSGQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RDSGDNSAPSGQER 14 1 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 RDS(1)GDNSAPSGQER;RDS(1)GDNSAPSGQER 106.87 0.00038285 19320800.0 52317.0 47166.0 36016.0 38277.0 45429.0 36481.2 43034.0 42097.0 27742.2 33763.1 True False 61173.23479214928 51848.328770765285 36874.75803144062 36132.46378570836 36527.51356480517 34568.06165051777 38957.50798082061 40991.99835545843 28147.877191913936 39884.08276144743 1.5337756457390632 1.2999754584022345 0.9245482277226726 0.9059369373447032 0.9158418856785953 0.8667132163292918 0.9767683066408018 1.0277783897059287 0.7057421217449209 1.0 15.283525479310807 -5.081404700210419 2.361239043448183 0.9128767538141163 1.541689807711941 0.8556234485285699 0.08494007175195376 0.11538332285471282 1.1257043134038869 0.02222327097962893 0.1134263083527902 8.290778257316585e-06 5.081404700210419 0.6288130538978247 RDS(ph)GDNSAPSGQER ddPTM_PC-9_Lapatinib_30min_R1 2 RDSGDNSAPSGQER 14 1 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 RDS(0.998)GDNS(0.002)APSGQER;RDS(0.999)GDNS(0.001)APSGQER 212.43 9.1485e-12 16097700.0 7556.7 11944.1 9207.6 9942.599999999999 10600.3 12267.4 9442.2 11144.1 11066.1 9439.900000000001 True False 7448.940072270944 11916.444170293316 8450.586670363838 10673.811971541301 9976.81119499165 11742.751898706108 9931.070914960575 11661.895569537208 9819.719286800942 11071.57413712391 0.6727986445300518 1.0763098383938456 0.76326876067499 0.9640735670776138 0.9011194859399958 1.060621710451424 0.8969881601262885 1.0533186541590236 0.8869307259456997 1.0 13.434572736119799 -4.74461874888367 24.89628888520455 0.9514775868425613 0.6727977830669445 0.45698776895677007 0.0924522271187598 866.0770305552967 1281812.1506295144 0.021499030456470662 0.5976509629549368 1.8004507709408006e-05 4.74461874888367 -0.27867980377561685 RDS(ph)GRPPGDSSGQAVAPSEGANK ddPTM_PC-9_Lapatinib_30min_R1 2 RDSGRPPGDSSGQAVAPSEGANK 23 2 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 RDS(1)GRPPGDSSGQAVAPSEGANK;RDS(1)GRPPGDSSGQAVAPSEGANK 91.337 0.00071944 0.0 16968.4 10606.1 13160.9 11407.1 10437.7 6298.5 6700.200000000001 9003.3 13245.2 9796.400000000001 True False 16726.427504376537 10581.542227086838 12078.86160454314 12246.01618697008 9823.77500730775 6029.127837520619 7047.103571669616 9421.626186162572 11753.386097860655 11489.694687117526 1.455776498842092 0.9209593914580754 1.051277856676749 1.0658260746215091 0.8550074893045123 0.5247422148023304 0.6133412386989681 0.820006661859021 1.0229502539383213 1.0 13.488052841655868 -1.5228787452831343 0.6067956197148275 0.7988019877396608 40.55375509666454 0.5053781536696501 0.17303868757775615 155.31735509477764 1.1749135653573175 0.08405591136668773 8202.96060672026 0.02999999999980681 1.5228787452831343 39.75495310892488 RDS(ph)GS(ph)S(ph)QS(ph)DDPS(ph)SSNK ddPTM_PC-9_AZD4547_30min_R2 1 RDSGSSQSDDPSSSNK 16 1 A6NKL6 A6NKL6 TMEM200C Transmembrane protein 200C 5 RDS(0.994)GS(0.979)S(0.89)QS(0.896)DDPS(0.387)S(0.438)S(0.417)NK 40.856 0.044933 0.0 555.7 0.0 1026.6 2349.1 2062.0 716.75 700.14 802.25 1101.4 582.34 True False 732.4010407219544 0.0 1012.9866132314764 1807.5512882332087 1775.726892710841 671.9315091940261 762.4511036490992 678.2806963710175 1159.6177554473347 561.9524538505007 1.3033149614412025 0.0 1.8026197880096222 3.2165555570544435 3.159923727609965 1.1957088265919091 1.356789348324366 1.2070072685392423 2.0635513689843843 1.0 9.134304260619736 -5.35990291786394 7.152423681653401 1.9400712865339937 0.6588252760630948 0.27345115346764837 0.7940527838827597 0.3199875633550037 19.976643285476975 0.22570929856004085 0.47379481385327327 4.366134218437895e-06 5.35990291786394 -1.281246010470899 RDS(ph)GVGSGLEAQESWER ddPTM_PC-9_AZD4547_30min_R2 2 RDSGVGSGLEAQESWER 17 1 A0A0A0MTG6;Q12770-4;Q12770-2;Q12770 A0A0A0MTG6 SCAP Sterol regulatory element-binding protein cleavage-activating protein 1 RDS(1)GVGSGLEAQESWER;RDS(1)GVGSGLEAQESWER 117.29 0.00018821 7591100.0 11611.8 14222.199999999999 17527.300000000003 17817.6 13992.9 12174.8 15552.3 18303.7 14537.3 14199.4 True False 15304.110859555847 18819.248019720606 17294.876549865618 13710.027599175864 12050.227370035647 11413.507831371368 16936.424571202748 15475.283742182859 15305.71199951384 13702.283327960984 1.1169022339748413 1.3734388327321991 1.2621893837630376 1.000565181074535 0.8794320684820363 0.8329639344182058 1.236029365751192 1.1293945229262539 1.1170190860293252 1.0 13.74212870130788 -5.757265211204679 24.879920219055073 1.027668004660979 1.2631030925965054 0.39875597959790354 0.12517168962284156 105.283533348325 627525.5106908391 0.037537805133746806 0.062126955260841804 1.7487784335659297e-06 5.757265211204679 0.23543508793552648 RDS(ph)GVGSGLEAQESWER ddPTM_PC-9_Lapatinib_30min_R1 1 RDSGVGSGLEAQESWER 17 1 A0A0A0MTG6;Q12770-4;Q12770-2;Q12770 A0A0A0MTG6 SCAP Sterol regulatory element-binding protein cleavage-activating protein 1 RDS(0.999)GVGS(0.001)GLEAQESWER 104.16 0.00036983 2363300.0 6253.3 9265.4 8120.3 9677.2 9273.5 8861.3 8051.3 8035.2 9524.0 6138.4 True False 6164.126795285228 9243.94653556448 7452.680279264468 10388.893570192859 8728.05096240249 8482.32285569921 8468.15691868654 8408.54472593977 8451.30682783385 7199.4142610961335 0.8561983755532245 1.2839859188984994 1.0351786977361368 1.4430192781559867 1.2123279263935032 1.178196245982899 1.1762285946575377 1.167948449831187 1.1738881138570727 1.0 12.813663819413295 -9.610595570861017 1.102234384997664 0.9986042816257811 1.1801145399151485 0.10775676416579694 0.14387622088625898 29.848237493709025 27.617216559000887 0.3076768878947583 0.040937838606054766 2.4513449513824124e-10 9.610595570861017 0.1815102582893674 RDS(ph)IVAELDR ddPTM_PC-9_AZD4547_30min_R2 3 RDSIVAELDR 10 1 M0QXB4;O14579-3;O14579 M0QXB4 COPE Coatomer subunit epsilon 1 RDS(1)IVAELDR;RDS(1)IVAELDR;RDS(1)IVAELDR 111.72 0.00071291 28786500.0 23630.9 15409.699999999999 22011.6 20332.5 18306.9 21430.6 23695.5 27123.5 27330.4 25353.7 True False 31145.03464674544 20390.58417189243 21719.71180187605 15645.15625899354 15765.302935096059 20090.54119418694 25804.353595734025 22932.186311024365 28775.029147882546 24466.07468006569 1.2729886201206437 0.8334227880251727 0.8877481200354831 0.6394632757228033 0.6443740216300905 0.821159154335296 1.0546993718104984 0.9373054979558656 1.176119566549336 1.0 14.57849503454804 -7.260203417270815 24.417654183279197 1.036806574647209 0.8319307276978375 0.22343151623502855 0.17348504020188873 126.99464763958785 2508949.6852964675 0.07207704117172058 0.05267401848538103 5.49283537110312e-08 7.260203417270815 -0.20487584694937155 RDS(ph)IVAELDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RDSIVAELDR 10 1 M0QXB4;O14579-3;O14579 M0QXB4 COPE Coatomer subunit epsilon 1 RDS(1)IVAELDR;RDS(1)IVAELDR;RDS(1)IVAELDR;RDS(1)IVAELDR 100.73 0.0017769 52065200.0 36882.4 39137.100000000006 43213.4 37138.299999999996 43757.9 31349.0 38490.7 32538.5 32485.999999999996 28416.9 True False 43125.861859394965 43022.37263991688 44243.771343732114 35057.56145499314 35183.853613713436 29705.00325323954 34844.58224746415 31684.398852390514 32961.04629252605 33568.65902194339 1.2847061251747993 1.2816232132416645 1.3180083039602666 1.0443539443168246 1.0481161487777695 0.8849028861659851 1.038009359405352 0.9438684706374132 0.9818994041727984 1.0 15.034827285931556 -5.852997112382971 3.4791518372752823 0.9817692137988928 1.295856983796279 0.9034999816240895 0.04563497488372802 0.06431153613058899 1.5240962832669944 0.01319676207928385 0.021077569259112933 1.4028230318787394e-06 5.852997112382971 0.3140877699973862 RDS(ph)IVAELDR ddPTM_PC-9_Lapatinib_30min_R1 3 RDSIVAELDR 10 1 M0QXB4;O14579-3;O14579 M0QXB4 COPE Coatomer subunit epsilon 1 RDS(1)IVAELDR;RDS(1)IVAELDR;RDS(1)IVAELDR 111.72 0.00071291 27810600.0 22106.6 25672.3 32003.1 26096.1 23295.6 29279.100000000002 24824.5 27094.1 32793.0 28835.699999999997 True False 21791.35583014606 25612.857366651402 29371.928653538493 28015.29424803761 21925.398608911764 28026.9011459157 26109.791142788636 28352.99079787494 29099.507014401024 33819.91232384496 0.6443350775567185 0.7573306849939077 0.8684803311222546 0.8283668502678299 0.6482985052995869 0.8287100474283353 0.7720242114400677 0.8383519899868123 0.8604252647303351 1.0 15.045585299199237 -14.522878745280302 0.12385798278752842 1.7472193863498315 0.6818565618427205 0.5481894337544195 0.06757692406347254 125.98068471141144 0.997531060238961 23.19260923599981 0.6226228024037751 3.0000000000002464e-15 14.522878745280302 -1.065362824507111 RDS(ph)LASLFPSEEEER ddPTM_PC-9_AZD4547_30min_R2 1 RDSLASLFPSEEEER 15 1 Q6P597;Q6P597-3;Q6P597-2;K7ENJ3;K7EL76 Q6P597 KLC3 Kinesin light chain 3 1 RDS(0.998)LAS(0.002)LFPSEEEER 103.67 0.0026595 0.0 2702.3 3923.2 4217.9 5242.7 5430.0 4359.7 3050.8 6787.9 5271.9 3240.2 True False 3561.575188668235 5191.297677642554 4161.9678900731005 4034.0765139075575 4676.138228622627 4087.0872698056432 3322.315289817285 5738.986025424538 5550.561871202839 3126.761584240122 1.139061963220897 1.6602793458280778 1.331079386113335 1.2901772025857656 1.4955211974561344 1.3071310874503095 1.0625419304633958 1.8354408773444264 1.7751791179664755 1.0 11.610453502534684 -7.768189835367159 24.99985038309816 1.6039823867843273 1.3439063277079977 0.09990190380788722 0.2638723628070032 289.4536122496683 1071949.4312553625 0.13400517250374974 0.06665831236897322 1.7053368027345078e-08 7.768189835367159 -0.2600760590763296 RDS(ph)LASLFPSEEEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RDSLASLFPSEEEER 15 1 Q6P597;Q6P597-3;Q6P597-2;K7ENJ3;K7EL76 Q6P597 KLC3 Kinesin light chain 3 1 RDS(0.968)LAS(0.031)LFPS(0.001)EEEER;RDS(0.998)LAS(0.002)LFPSEEEER;RDS(0.95)LAS(0.05)LFPSEEEER;RDS(0.82)LAS(0.043)LFPS(0.136)EEEER 136.43 1.9115000000000002e-06 6411400.0 24554.699999999997 31652.4 29477.4 24902.5 28417.699999999997 20681.1 24783.3 23246.9 18981.699999999997 16444.3 True False 28711.325732568515 34794.641088575896 30180.25300966204 23507.29365999432 22849.455683166336 19596.546709004175 22435.64640844615 22636.69350712656 19259.271452651672 19425.521416992815 1.4780208528895795 1.7911818345395185 1.5536392749417443 1.21012420492512 1.176259581026143 1.0088041545109698 1.1549572300705493 1.1653068672496336 0.9914416730046838 1.0 14.24566570331056 -5.800386391379221 2.4906453869752285 1.093671672083314 1.6483573169963732 0.8578258419629681 0.09596461552650559 0.09268364150736351 1.1720452367741756 0.027574765019013913 0.04886954456499566 1.5834837416118548e-06 5.800386391379221 0.5546856449130593 RDS(ph)LASLFPSEEEER ddPTM_PC-9_Lapatinib_30min_R1 1 RDSLASLFPSEEEER 15 1 Q6P597;Q6P597-3;Q6P597-2;K7ENJ3;K7EL76 Q6P597 KLC3 Kinesin light chain 3 1 RDS(0.972)LAS(0.028)LFPSEEEER 81.643 0.0039475000000000005 1757500.0 10387.0 14126.0 17458.0 14255.0 12097.0 22964.0 10924.0 9934.7 21896.0 9351.0 True False 10238.87947525749 14093.292114898855 16022.670629828834 15303.360253285991 11385.478243617068 21981.883251698586 11489.591268457487 10396.302430405447 19429.841904898156 10967.307890575712 0.9335818395374706 1.2850274885607365 1.460948373994062 1.3953615970274966 1.0381288058303435 2.0043098516991376 1.0476218396613608 0.947935677025997 1.7716145200586884 1.0 13.420921815084517 -10.852612470751227 3.8093434188825976 0.9991131628811352 1.3186154004370119 0.07496328129592711 0.3377020025483646 41581490.79255715 39490185.051412754 270734.4076247 0.07900732132305634 1.4040660206337156e-11 10.852612470751227 0.3195022375558767 RDS(ph)LDKSGLFPEWK ddPTM_PC-9_AZD4547_30min_R2 1 RDSLDKSGLFPEWK 14 2 Q96C24-2;Q96C24 Q96C24-2 SYTL4 Synaptotagmin-like protein 4 1 RDS(0.837)LDKS(0.163)GLFPEWK 62.287 0.015613 4574600.0 35462.0 25917.0 39571.0 55828.0 48660.0 33639.0 26793.0 35392.0 32723.0 43256.0 True False 46738.17834457791 34294.16341544201 39046.2626847679 42957.71713400181 41904.39893273979 31535.548012246738 29177.525095081437 29922.9796272522 34452.67097467147 41741.62060610169 1.11970205435066 0.8215819826226145 0.9354275688821772 1.02913390784167 1.003899664753656 0.7554940980810156 0.6990031692927691 0.7168619519980527 0.8253793330112166 1.0 15.349198993343764 -6.763363472958044 24.999731221393482 0.7753800241033207 0.9730766247044351 0.41571991286587273 0.10609754852090662 46.92186139567979 609648.8266166708 0.03556139642058164 0.03295171692474237 1.7243940952055556e-07 6.763363472958044 0.19769660060111438 RDS(ph)LEEGELR ddPTM_PC-9_AZD4547_30min_R2 2 RDSLEEGELR 10 1 P21127;P21127-8;A0A0D9SEN2;A0A0D9SER5;A0A0D9SEI3;P21127-9;P21127-2;P21127-3;P21127-6;E7ESP2;J3KS35;A0A087WYI9;A0A087X1I0;E9PFJ2;Q5QPR4;Q5QPR3;Q9UQ88-4;Q9UQ88-3;Q9UQ88-2;Q9UQ88 P21127;Q5QPR4 CDK11B;CDK11A Cyclin-dependent kinase 11B;Cyclin-dependent kinase 11A 1 RDS(1)LEEGELR;RDS(1)LEEGELR 109.79 0.00084031 18934800.0 20361.1 26340.0 27763.0 25905.0 30572.0 28486.0 29055.0 29608.0 26109.0 32332.0 True False 26835.506262810486 34853.88989322613 27394.844479978055 19933.002478260303 26327.60551113279 26704.765916848286 31640.838713006804 25032.763924154682 27489.068437420075 31200.066521094883 0.8601105463883083 1.1171094737782317 0.8780380151258955 0.6388769224188439 0.8438317108501118 0.8559201596186582 1.0141272837227417 0.8023304664183846 0.8810580073229735 1.0 14.929261484584133 -5.497269059522634 24.604166997438853 0.8515984003156745 0.9908509941690491 0.15650885598133135 0.11406031959996679 955.5636891853533 918043.0633787235 0.02981471834176074 0.06164990993021168 3.1822254190010065e-06 5.497269059522634 0.13925259385337463 RDS(ph)LEEGELR ddPTM_PC-9_Lapatinib_30min_R1 2 RDSLEEGELR 10 1 P21127;P21127-8;A0A0D9SEN2;A0A0D9SER5;A0A0D9SEI3;P21127-9;P21127-2;P21127-3;P21127-6;E7ESP2;J3KS35;A0A087WYI9;A0A087X1I0;E9PFJ2;Q5QPR4;Q5QPR3;Q9UQ88-4;Q9UQ88-3;Q9UQ88-2;Q9UQ88 P21127;Q5QPR4 CDK11B;CDK11A Cyclin-dependent kinase 11B;Cyclin-dependent kinase 11A 1 RDS(1)LEEGELR;RDS(1)LEEGELR 113.52 0.00059359 33420000.0 45058.0 65762.0 44854.0 44406.0 46182.0 48424.0 57458.0 45114.0 44687.0 45149.0 True False 44415.46465737476 65609.73212940522 41166.27726144706 47671.76537407346 43465.66555730539 46353.018401857364 60432.89409584684 47210.16113675414 39653.87948502848 52952.94449273903 0.838772330469084 1.2390195249369316 0.7774124301452553 0.9002665636584245 0.8208356678496972 0.875362434438624 1.1412565377574702 0.891549310222544 0.7488512653052914 1.0 15.692423288261176 -5.283924179557775 24.99894251381106 0.8962811931456984 1.0388960559481648 0.1474395809033342 0.13888942413880576 1314.8206786461742 1461835.6855078454 0.035741386973047025 0.0744950247791432 5.200867869299852e-06 5.283924179557775 0.14261486280246638 RDS(ph)LGAYASQDANEQGQDLGK ddPTM_PC-9_Lapatinib_30min_R1 2 RDSLGAYASQDANEQGQDLGK 21 1 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RDS(0.993)LGAY(0.007)ASQDANEQGQDLGK;RDS(0.981)LGAY(0.019)ASQDANEQGQDLGK 106.0 3.6008000000000005e-05 19016000.0 24847.3 47843.0 56761.0 40073.0 65378.0 55179.0 58524.0 67877.0 56727.0 50388.0 True False 24492.972945563237 47732.22247296516 52094.3296837962 43020.10209960919 61532.594578093434 52819.122798531476 61554.08635986875 71030.81321717132 50337.807898207764 59097.498662210346 0.4144502474725748 0.8076860028508673 0.8814980475156338 0.7279513189805819 1.0412047205212798 0.8937624094792095 1.0415683870429064 1.2019258822301337 0.8517756087432524 1.0 15.850809448294166 -4.477800668884146 0.5944795300463324 1.018808111598184 3.5696660300412884e-16 0.6559536486891814 0.1196080174303471 3.2691256074301958 0.6765407528797979 0.05942237192686668 2.472499445097806 3.328122713742237e-05 4.477800668884146 -1.0188081115981835 RDS(ph)LGAYASQDANEQGQDLGKR ddPTM_PC-9_AZD4547_30min_R2 4 RDSLGAYASQDANEQGQDLGKR 22 2 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RDS(0.997)LGAY(0.001)AS(0.002)QDANEQGQDLGKR;RDS(0.999)LGAY(0.001)ASQDANEQGQDLGKR;RDS(1)LGAYASQDANEQGQDLGKR;RDS(1)LGAYASQDANEQGQDLGKR 115.81 4.2939e-06 234271000.0 58650.0 58699.2 76315.8 83970.4 89173.6 106958.4 88780.4 80896.9 70642.2 88810.4 True False 77299.4800042157 77672.56847458081 75303.80262814203 64612.32160974752 76793.38488838001 100270.27433969775 96681.68360957578 68396.14293082771 74376.2024730903 85701.17492778199 0.901965230574188 0.9063185952821923 0.8786787659748944 0.7539257386400424 0.8960598842792024 1.1699988293531884 1.1281255325968023 0.7980770740711928 0.8678551085882437 1.0 16.387027362777133 -6.540104812193602 24.978693224925625 0.993579509193282 0.8598529576676571 0.25353190804058223 0.10899676347783846 378.5363708321227 548893.6670760576 0.039794777216420475 0.03980322882900629 2.8833355578461326e-07 6.540104812193602 -0.13372655152562485 RDS(ph)LGAYASQDANEQGQDLGKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RDSLGAYASQDANEQGQDLGKR 22 2 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RDS(0.937)LGAY(0.03)AS(0.033)QDANEQGQDLGKR;RDS(1)LGAYASQDANEQGQDLGKR;RDS(0.998)LGAY(0.002)ASQDANEQGQDLGKR 99.859 0.00028719 60701200.0 42511.0 46513.0 55283.0 60917.0 76874.0 59782.0 63105.0 61364.0 57393.0 41084.0 True False 49707.27266947758 51130.50324629196 56601.15638194505 57504.01798557872 61811.091544626426 56646.926679803706 57127.23755936431 59753.26002053234 58232.26404811145 48532.203979234946 1.0242121435644134 1.0535376317994691 1.1662597562262471 1.184863106777151 1.2736098193907082 1.1672028474956697 1.177099593165125 1.2312084579158706 1.1998685259178994 1.0 15.56665475784057 -5.2512012743974195 2.698742599962926 1.189331094899114 1.026361848104944 0.38893425817377036 0.06744902358936153 0.24659341946014787 3.4864458958065208 0.017127647202811874 0.05503561883241695 5.60788017790969e-06 5.2512012743974195 -0.16296924679417013 RDS(ph)LGAYASQDANEQGQDLGKR ddPTM_PC-9_Lapatinib_30min_R1 2 RDSLGAYASQDANEQGQDLGKR 22 2 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RDS(0.986)LGAY(0.013)ASQDANEQGQDLGKR;RDS(0.996)LGAY(0.003)ASQDANEQGQDLGKR 76.329 0.0018149999999999998 145732000.0 124581.0 173531.0 172837.0 131192.0 183164.0 170203.0 181028.0 171467.0 169667.0 149844.0 True False 122804.45209464234 173129.19963121286 158627.00903011407 140840.29732368275 172390.65363427938 162923.8144525716 190400.74406319307 179433.98279105866 150557.3157872832 175744.33574542069 0.6987676249921029 0.98511965632852 0.9026009763404131 0.8013930959783584 0.9809172677064292 0.9270501593210912 1.083396191721384 1.0209944009289877 0.8566837454458684 1.0 17.423118666302592 -6.2820691594235205 23.0675433253572 0.9819283374154325 0.8608117742188706 0.3420452062725641 0.0882241399312171 376.7378586542258 421254.21912526304 0.027193191839800915 0.030882804531353752 5.223130064023352e-07 6.2820691594235205 -0.12111656319656194 RDS(ph)LGTYSSR ddPTM_PC-9_AZD4547_30min_R2 1 RDSLGTYSSR 10 1 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RDS(0.998)LGT(0.002)YSSR 87.831 0.0047567 34280000.0 0.0 14592.0 15236.0 24533.0 43856.0 28644.0 32833.0 31576.0 9580.2 26526.0 True False 0.0 19308.578637887465 15033.960684974441 18877.295881071626 37767.3514096637 26852.886151871196 35755.07339405103 26696.654744295753 10086.589813634071 25597.332813886016 0.0 0.754319943342416 0.5873252808909385 0.7374712052355349 1.4754408861370003 1.0490501626522615 1.3968280857236288 1.0429467373965375 0.394048469306236 1.0 14.643705871936987 -5.105559823164131 1.0129668154027576 1.059287908603524 2.843995015571087e-10 0.46216650855939045 0.3120374213279981 1.159613689770408 1.3681199748835324 0.11013897127290664 1.188788830568841 7.842240862001446e-06 5.105559823164131 -1.0592879083191247 RDS(ph)LGTYSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RDSLGTYSSR 10 1 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RDS(0.999)LGTYSSR;RDS(0.997)LGT(0.002)YSS(0.001)R 74.78 0.011648 51427000.0 46530.0 46112.0 50316.0 54830.0 68191.0 51644.0 59879.0 37110.0 37447.0 53262.0 True False 54406.6099906093 50689.69461640865 51515.7242644926 51758.05286125844 54829.4630631893 48935.69772593394 54206.827633581765 36135.90182129516 37994.591532236154 62917.97897823998 0.8647227847135027 0.8056472162581628 0.8187758904701815 0.8226273904818021 0.8714434880712225 0.7777697014530334 0.8615475022223624 0.5743334800024754 0.6038749519493702 1.0 15.941184709475031 -7.736230366506805 24.997895122503163 0.6918280387997918 0.8293794700119888 0.13842003802662384 0.11133231883803661 293.7376949640927 291278.06559649087 0.04917944652692588 0.02837972974088572 1.8355644310558993e-08 7.736230366506805 0.13755143121219693 RDS(ph)LGTYSSR ddPTM_PC-9_Lapatinib_30min_R1 2 RDSLGTYSSR 10 1 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RDS(0.996)LGT(0.003)YS(0.001)SR;RDS(0.986)LGT(0.014)YS(0.001)SR 96.756 0.007945 24788000.0 120534.0 153596.0 201676.0 153217.0 185875.0 191213.0 173639.0 188760.0 194407.0 154010.0 True False 118815.1630567716 153240.3578989103 185094.97777187292 164485.08929692875 174942.19794431038 183035.26572927358 182629.17779784778 197530.4787022594 172510.83646353375 180630.42329457446 0.6577804607311709 0.8483640524332046 1.0247165145044121 0.910616751579463 0.968509040467742 1.0133136068157094 1.0110654366347451 1.0935615113968045 0.9550486198119617 1.0 17.462681378549668 -4.256302732088925 1.0082593820922576 1.0060791074128475 6.028554832077428e-14 0.8327344026034086 0.047350468853322794 1.8273401181777595 0.7193771662316024 0.015504014480228223 2.5642493886654796 5.5423923672697825e-05 4.256302732088925 -1.006079107412787 RDS(ph)LTGSSDLYK ddPTM_PC-9_AZD4547_30min_R2 3 RDSLTGSSDLYK 12 1 Q5T1Z4;Q5T1Z8;Q14671-2;Q14671;Q14671-3;E9PR38;Q14671-4;H0YDK8 Q5T1Z4 PUM1 Pumilio homolog 1 1 RDS(0.99)LT(0.01)GSSDLYK;RDS(0.996)LT(0.004)GSSDLYK;RDS(1)LTGSSDLYK 152.11 0.00028832 190490000.0 408844.0 427978.0 434006.0 452382.0 441390.0 465169.0 424734.0 503172.0 488346.0 443155.0 True False 538847.8875165139 566313.5189340607 428250.7968655169 348092.31913222774 380110.61744599364 436081.9088946991 462534.5031812165 425418.32914228406 514158.97258188133 427640.27833588386 1.2600494266194535 1.3242754427571903 1.0014276450572168 0.8139839410983258 0.8888559770963419 1.019740026808665 1.0815971427694318 0.9948041629702274 1.2023165230896296 1.0 18.706038217623288 -2.928685682792365 7.623791384862127 1.0523862493095946 1.1691391373745657 0.0 0.15286610922042448 0.0 0.0 0.0386607698091032 0.0 0.0011784585650517901 2.928685682792365 0.11675288806497108 RDS(ph)LTGSSDLYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RDSLTGSSDLYK 12 1 Q5T1Z4;Q5T1Z8;Q14671-2;Q14671;Q14671-3;E9PR38;Q14671-4;H0YDK8 Q5T1Z4 PUM1 Pumilio homolog 1 1 RDS(0.946)LT(0.023)GS(0.023)S(0.007)DLYK;RDS(0.991)LT(0.009)GSSDLYK 110.6 0.00053806 59324600.0 529576.0 665965.0 530923.0 502158.0 585423.0 365131.0 424591.0 358680.0 306107.0 277361.0 True False 619222.7571972262 732077.6039906455 543582.2178566904 474023.7152782009 470713.5656441697 345982.8875836109 384370.6667073616 349265.03005287406 310583.2357774505 327644.3537115325 1.8899234800866054 2.234366610313046 1.659061759188061 1.4467629608399877 1.436660086804363 1.055970852738162 1.1731338030191498 1.0659882463910153 0.9479279354555791 1.0 18.32177114444486 -5.856367506147772 0.7344502795853816 1.0162295021585097 2.191995879824563 0.89661384187283 0.13067945205603265 0.26684963478520357 0.2632095439004017 0.06611400834618705 0.20734907828090887 1.3919783925713503e-06 5.856367506147772 1.1757663776660532 RDS(ph)LTGSSDLYK ddPTM_PC-9_Lapatinib_30min_R1 3 RDSLTGSSDLYK 12 1 Q5T1Z4;Q5T1Z8;Q14671-2;Q14671;Q14671-3;E9PR38;Q14671-4;H0YDK8 Q5T1Z4 PUM1 Pumilio homolog 1 1 RDS(0.973)LT(0.026)GSSDLYK;RDS(0.972)LT(0.026)GS(0.001)S(0.001)DLYK;RDS(0.998)LT(0.001)GSSDLYK 115.58 0.00032826 226438000.0 219027.0 405359.0 405377.0 366350.0 384951.0 380622.0 372991.0 347821.0 384754.0 362677.0 True False 215903.63481536767 404420.4161406823 372048.4678604715 393292.6011077735 362308.93902278546 364343.68433321815 392302.6489210201 363982.0334429878 341418.9528807632 425365.2362132744 0.5075723553184668 0.9507603859237557 0.874656497960566 0.9245997736180303 0.8517596366082134 0.8565431617701345 0.9222724743879234 0.8556929491541486 0.8026489327622879 1.0 18.698342605544276 -4.7556067037848395 24.995019556167353 0.8875726933161149 0.5075717409866084 0.817340924464699 0.05463359664131323 74.26125146913776 318202.9423968512 0.012939218747118675 0.11294163582688882 1.755469531922891e-05 4.7556067037848395 -0.3800009523295065 RDS(ph)PLQGSGQQNSQAGQR ddPTM_PC-9_AZD4547_30min_R2 6 RDSPLQGSGQQNSQAGQR 18 1 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6;E7EN19 C9J840;O95819-6;E7EN19 MAP4K4 1 RDS(1)PLQGSGQQNSQAGQR;RDS(0.994)PLQGS(0.005)GQQNSQAGQR;RDS(1)PLQGSGQQNSQAGQR;RDS(1)PLQGSGQQNSQAGQR;RDS(1)PLQGSGQQNSQAGQR;RDS(1)PLQGSGQQNSQAGQR 212.34 4.3752e-21 75388000.0 100493.09999999999 98872.20000000001 140566.2 166869.7 147862.9 146864.0 111720.9 150675.5 123485.9 145415.59999999998 True False 132447.81541366802 130830.7050987485 138702.20034367664 128400.46877616503 127334.68863443915 137680.57086330143 121663.84366793885 127392.06365353831 130013.11257253871 140324.64410506407 0.9438671037319825 0.9323430387665387 0.9884379271243854 0.9150243679223504 0.907429264806123 0.9811574562784355 0.8670169409219847 0.9078381382400452 0.9265166029938056 1.0 17.098408874741402 -5.820745218266737 24.99997103028688 0.9240995604901444 0.9526305425885916 0.07400318503348213 0.03830927576856269 166.50755947147476 70188.90597022788 0.010479870101916484 0.015544167483867614 1.5109663125947378e-06 5.820745218266737 0.028530982098447177 RDS(ph)PLQGSGQQNSQAGQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RDSPLQGSGQQNSQAGQR 18 1 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6;E7EN19 C9J840;O95819-6;E7EN19 MAP4K4 1 RDS(1)PLQGSGQQNSQAGQR;RDS(1)PLQGSGQQNSQAGQR;RDS(1)PLQGSGQQNSQAGQR;RDS(1)PLQGSGQQNSQAGQR;RDS(1)PLQGSGQQNSQAGQR 211.26 1.4846999999999998e-43 58321200.0 218091.6 216054.7 244941.3 228584.2 276222.0 206480.6 200850.0 205288.1 188878.9 172925.5 True False 255010.20037455374 237503.1827602308 250781.62953705253 215777.36835397524 222098.281976218 195652.3938476776 181824.0339719249 199899.50489572115 191640.8965887276 204275.52427249486 1.2483639500265384 1.1626609874387674 1.2276636196636093 1.0563055418530582 1.087248620544223 0.9577867664002938 0.8900921175920193 0.9785778575658615 0.9381490869806154 1.0 17.640156829139165 -6.186430313228558 1.0789007116761598 0.9451390443780001 1.2206912164626968 0.8488688576968508 0.04583338258999785 0.17997940663998555 0.4345346394812595 0.019023685890567313 0.03130662084669753 6.50983059020414e-07 6.186430313228558 0.27555217208469673 RDS(ph)PLQGSGQQNSQAGQR ddPTM_PC-9_Lapatinib_30min_R1 5 RDSPLQGSGQQNSQAGQR 18 1 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6;E7EN19 C9J840;O95819-6;E7EN19 MAP4K4 1 RDS(1)PLQGSGQQNSQAGQR;RDS(1)PLQGSGQQNSQAGQR;RDS(1)PLQGSGQQNSQAGQR;RDS(1)PLQGSGQQNSQAGQR;RDS(1)PLQGSGQQNSQAGQR 197.28 4.2132999999999995e-34 58265300.0 190602.4 189747.5 200201.2 172908.1 170511.0 152402.1 134266.1 132949.0 163834.1 124879.8 True False 187884.37482380075 189308.1513218016 183741.43013498033 185624.33847851248 160481.87821752412 145884.21744964694 141217.7416889273 139126.29589418627 145381.37840844324 146465.10703812572 1.282792732161752 1.2925136583727317 1.2545065090974288 1.2673621877065464 1.0957004126296768 0.9960339387296692 0.9641732733801743 0.9498937918228598 0.9926007726236095 1.0 17.160197481071236 -6.452662361747161 1.9478867676591063 0.9725062792141053 1.281010475701345 0.9847857772239532 0.017214885446429178 0.03592960504247524 0.27156477875894397 0.006295103465605809 0.00716965792403911 3.5264492505370193e-07 6.452662361747161 0.3085041964872397 RDS(ph)PPPPAR ddPTM_PC-9_AZD4547_30min_R2 3 RDSPPPPAR 9 1 O96013;O96013-2;O96013-4;M0R2X4 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 RDS(1)PPPPAR;RDS(1)PPPPAR;RDS(1)PPPPAR 94.538 0.00262 181967000.0 37933.0 35885.0 57930.0 70154.0 51985.0 52899.0 51973.0 56207.0 37516.0 48711.0 True False 49994.904944585025 47484.12448057785 57161.8103492104 53981.079168495446 44767.78007641754 49591.21716756858 56598.49631495795 47521.499658368084 39499.01916956805 47005.64271647449 1.0635936890841162 1.0101792409687798 1.2160627330211227 1.1483957254684278 0.9523916170329775 1.055005618510305 1.2040787668056152 1.0109743620570217 0.8403037781616051 1.0 15.520546332731971 -8.001859600170315 24.992515069566416 0.921980924828059 1.0909360878111398 0.39931652172214427 0.08501325165937867 66.7552738635629 897163.3298715827 0.048587456794139304 0.022782811521468816 9.957272665793189e-09 8.001859600170315 0.16895516298308078 RDS(ph)PPPPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RDSPPPPAR 9 1 O96013;O96013-2;O96013-4;M0R2X4 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 RDS(1)PPPPAR;RDS(1)PPPPAR;RDS(1)PPPPAR;RDS(1)PPPPAR 89.35600000000001 0.0043132 253779000.0 90543.4 98941.7 121459.6 116297.3 133349.0 140273.4 113401.7 107006.3 126411.3 101876.5 True False 105870.6093063344 108763.97809308476 124355.65750209788 109781.53932193395 107220.22070380622 132917.21596679214 102659.47001879034 104197.4980075468 128259.82611581606 120345.90299606993 0.8797192648078079 0.9037613693973164 1.0333185792470134 0.9122166736786962 0.8909337005623503 1.1044598333449935 0.8530366839504526 0.8658167450116646 1.065759805051316 1.0 16.876827502598516 -1.5228787452826913 0.010325085258833027 1.7824718379521611 3.297712084418331e-05 0.0778553004369058 0.08325970670229764 40441.56730842842 32.402123979415336 2399.1092354412112 3254.8460298852783 0.02999999999983741 1.5228787452826913 -1.7824388608313169 RDS(ph)PPPPAR ddPTM_PC-9_Lapatinib_30min_R1 4 RDSPPPPAR 9 1 O96013;O96013-2;O96013-4;M0R2X4 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 RDS(1)PPPPAR;RDS(1)PPPPAR;RDS(1)PPPPAR;RDS(1)PPPPAR 98.182 0.0020832 210278000.0 114334.0 93764.0 119815.0 94147.0 108358.0 101075.0 99195.0 104913.0 109027.0 83827.0 True False 112703.5761937124 93546.89521884316 109964.27319927503 101070.88444518519 101984.59548002471 96752.25786733297 104330.83173513749 109787.64098373645 96747.23115479229 98316.38525754372 1.1463356377320104 0.951488350327296 1.1184735170156959 1.0280166849139738 1.0373102633184892 0.9840908777706436 1.0611744060955728 1.11667694755196 0.9840397498479936 1.0 16.585144253489453 -4.723836175131744 24.44108591350205 1.0371736054735385 1.1463369770985792 0.2933361059089984 0.05287266697874609 7346.319308193846 4774507.090124146 0.012544372085651794 3.5110386141073517 1.8887036728568507e-05 4.723836175131744 0.10916337162504064 RDS(ph)PTYDPYK ddPTM_PC-9_AZD4547_30min_R2 2 RDSPTYDPYK 10 1 F5H0Q6;A0A0A0MQS2;Q8N2M8-3;Q8N2M8;Q8N2M8-4 F5H0Q6 CLASRP CLK4-associating serine/arginine rich protein 1 RDS(0.811)PT(0.188)Y(0.001)DPYK;RDS(0.924)PT(0.065)Y(0.012)DPYK 93.561 0.0030783 17038800.0 191626.0 180372.0 222749.0 258260.0 245443.0 237980.0 227585.0 247842.0 224741.0 229344.0 True False 252559.08193159153 238673.72163329498 219795.20271838878 198722.14707722474 211367.4761045721 223099.0729794132 247839.6241094356 209543.7137425812 236620.3504421548 221314.73636688103 1.1411760738467758 1.0784357406622818 0.9931340602373027 0.8979164710830472 0.9550537825650298 1.008062439229416 1.1198514304921086 0.9468131999814662 1.0691576816190909 1.0 17.755739991439256 -5.051478083516999 2.9644303387303084 0.9965439017791587 1.136934608550711 0.38226550581019036 0.05893078636261627 0.2955859621794468 4.854410745721253 0.016368119958951682 0.0720696556010621 8.882227989672535e-06 5.051478083516999 0.1403907067715523 RDS(ph)PTYDPYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RDSPTYDPYK 10 1 F5H0Q6;A0A0A0MQS2;Q8N2M8-3;Q8N2M8;Q8N2M8-4 F5H0Q6 CLASRP CLK4-associating serine/arginine rich protein 1 RDS(0.98)PT(0.014)Y(0.003)DPY(0.003)K;RDS(0.997)PT(0.003)YDPYK;RDS(0.993)PT(0.007)YDPYK;RDS(0.936)PT(0.061)Y(0.003)DPYK 77.633 0.0098557 27304100.0 204447.0 254747.0 221044.0 256291.0 258967.0 212558.0 252997.0 224342.0 204098.0 183495.0 True False 239055.83908768726 280036.59859572904 226314.52727403812 241931.84617663285 208224.2753601641 201411.08429302636 229031.29262033917 218453.26020999724 207082.5471345195 216761.19095437886 1.1028535045187156 1.2919129912635863 1.044073093885473 1.1161215949747738 0.9606160329871434 0.9291842483713646 1.0566065429514213 1.0078061448553977 0.9553488160069373 1.0 17.725746953316943 -5.751343323013533 1.5133273061112382 0.9886357819217085 1.1905958796198588 0.5689312700760608 0.0661351592006404 0.27834191111079654 1.2849200304520518 0.020818814192821573 0.047983461554006096 1.7727874843095644e-06 5.751343323013533 0.20196009769815026 RDS(ph)PTYDPYK ddPTM_PC-9_Lapatinib_30min_R1 2 RDSPTYDPYK 10 1 F5H0Q6;A0A0A0MQS2;Q8N2M8-3;Q8N2M8;Q8N2M8-4 F5H0Q6 CLASRP CLK4-associating serine/arginine rich protein 1 RDS(0.97)PT(0.03)YDPYK;RDS(0.966)PT(0.03)Y(0.005)DPYK 77.204 0.010125 20668000.0 177955.0 190403.0 199349.0 205890.0 217847.0 179893.0 185702.0 208330.0 211226.0 178355.0 True False 175417.3290670502 189962.133551825 182959.29472939327 221031.83742890606 205033.66776368074 172199.395741065 195316.7409131354 218009.77234605612 187435.50357161186 209183.42410690064 0.8385814020206749 0.908112745371006 0.8746357198737418 1.056641262913597 0.9801621167597906 0.8231980926608439 0.9337104110759807 1.042194300417632 0.8960342071646424 1.0 17.674409010026302 -5.63230690384579 22.689652868788006 0.957942926657635 0.8771609219827209 0.2673143305318877 0.06643222052320046 6.857112339649923 1386.595670225342 0.01867234924729162 0.03234145886406549 2.331809654801643e-06 5.63230690384579 -0.08078200467491414 RDS(ph)PTYDPYKR ddPTM_PC-9_AZD4547_30min_R2 2 RDSPTYDPYKR 11 2 F5H0Q6;A0A0A0MQS2;Q8N2M8-3;Q8N2M8;Q8N2M8-4 F5H0Q6 CLASRP CLK4-associating serine/arginine rich protein 1 RDS(0.983)PT(0.016)YDPYKR;RDS(0.857)PT(0.08)Y(0.063)DPYKR 73.082 0.0081928 43088000.0 92751.0 88730.0 107902.0 102527.0 110984.0 125981.0 98686.0 126013.0 95837.0 117431.0 True False 122243.88865935238 117410.23729027915 106471.14897808564 78890.98417635962 95575.78732328798 118103.38815454813 107468.8628198862 106540.58634066804 100902.74816488686 113319.77643321459 1.0787515869429662 1.036096619547033 0.9395637048475364 0.696180196074198 0.8434166597532594 1.0422133882707822 0.948368115456205 0.9401764607562398 0.8904248785237786 1.0 16.790040134998158 -5.262233964816959 3.8790231044792516 0.9049533315367262 1.0638446887608224 0.30137098910160753 0.0891710534703622 0.2739344121862995 9.565854678100788 0.025614280520275593 0.06754843237334024 5.467213516853554e-06 5.262233964816959 0.1588913572240962 RDS(ph)PTYDPYKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RDSPTYDPYKR 11 2 F5H0Q6;A0A0A0MQS2;Q8N2M8-3;Q8N2M8;Q8N2M8-4 F5H0Q6 CLASRP CLK4-associating serine/arginine rich protein 1 RDS(0.995)PT(0.005)YDPYKR;RDS(0.948)PT(0.042)Y(0.01)DPYKR 73.36 0.0079713 34690000.0 72936.0 93932.0 92519.0 85421.0 94149.0 79658.0 91521.0 70313.0 72115.0 70295.0 True False 85282.62424833594 103256.94818503871 94725.00384026149 80635.13830861845 75701.17930425148 75480.59425010545 82851.46832533996 68467.35825278162 73169.54544682392 83038.92704508627 1.0270198241125086 1.2434764255681554 1.140730103470993 0.9710522664248459 0.9116348440189896 0.9089784386197934 0.9977425199672374 0.824521229851718 0.8811475298458067 1.0 16.341500182147776 -5.834107918932014 3.469312880517578 0.916845046808183 1.1505497510599623 0.6633445340276057 0.06884673643209382 0.12825605898642722 3.0722617536128936 0.0195736051230066 0.031633749949634464 1.4651837085176792e-06 5.834107918932014 0.23370470425177925 RDS(ph)QDGSSYR ddPTM_PC-9_AZD4547_30min_R2 5 RDSQDGSSYR 10 1 Q14847;Q14847-2;C9J9W2;Q14847-3;J3KSN1 Q14847 LASP1 LIM and SH3 domain protein 1 1 RDS(0.999)QDGSS(0.001)YR;RDS(0.979)QDGS(0.019)S(0.002)YR;RDS(0.999)QDGSSYR;RDS(0.917)QDGS(0.006)S(0.077)YR;RDS(0.955)QDGS(0.041)S(0.004)YR 126.5 0.00050553 495479500.0 186707.23 191813.45 185860.91 175007.93 148358.0 177415.11000000002 158483.68 221695.44 198514.09 179223.9 True False 246076.24538836282 253813.39659604573 183396.27289403862 134662.55558406512 127761.05254548734 166321.31512539092 172588.42049643004 187437.5038024051 209007.139522853 172949.3258125092 1.4228228079658953 1.4675593293216975 1.060404670746475 0.7786243453186399 0.7387195754899355 0.9616765740139191 0.9979132308589026 1.0837712313813945 1.2084877379021028 1.0 17.399989864274595 -5.33121824388009 4.146706286635339 0.9599992517187339 1.4490069487668655 0.680779351920051 0.12864491657649418 0.1294151490286549 4.309761275972363 0.038670062108067116 0.08913843038576177 4.664249311734517e-06 5.33121824388009 0.48900769704813163 RDS(ph)QDGSSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RDSQDGSSYR 10 1 Q14847;Q14847-2;C9J9W2;Q14847-3;J3KSN1 Q14847 LASP1 LIM and SH3 domain protein 1 1 RDS(0.999)QDGSSYR;RDS(0.889)QDGS(0.056)S(0.056)YR;RDS(0.987)QDGS(0.001)S(0.012)YR;RDS(0.964)QDGS(0.019)S(0.011)Y(0.006)R;RDS(0.94)QDGS(0.02)S(0.04)YR 141.34 0.00018329 340580070.0 195544.11 328950.8 255058.0 194072.4 211627.1 148691.52 177011.05 162151.3 143582.91999999998 127389.70000000001 True False 228645.86565077992 361606.86146389815 261139.55003285137 183199.15261920984 170160.28893284855 140893.874934739 160243.28189497697 157895.00018850365 145682.54857280297 150484.44419368965 1.519398678553699 2.4029517695428457 1.7353258765852018 1.217395948138087 1.1307500243269928 0.9362686999952862 1.0648494783203415 1.0492446646862437 0.9680904186036258 1.0 17.19925483554453 -5.754444213467351 2.68063657757501 1.0330321468312946 1.9852604030642949 0.7798313282317637 0.20668097750376202 0.10792948331393006 1.5820350099216998 0.05681403216178075 0.10261334271647335 1.7601747494272772e-06 5.754444213467351 0.9522282562330002 RDS(ph)QDGSSYR ddPTM_PC-9_Lapatinib_30min_R1 6 RDSQDGSSYR 10 1 Q14847;Q14847-2;C9J9W2;Q14847-3;J3KSN1 Q14847 LASP1 LIM and SH3 domain protein 1 1 RDS(0.999)QDGSS(0.001)YR;RDS(1)QDGSSYR;RDS(0.999)QDGSS(0.001)YR;RDS(0.941)QDGS(0.012)S(0.048)YR;RDS(0.993)QDGS(0.005)S(0.002)YR;RDS(0.998)QDGS(0.001)S(0.002)YR 136.01 0.00016824 529347200.0 136661.4 235434.0 210248.0 193945.9 226558.0 173860.3 179753.0 207204.0 193521.0 192163.6 True False 134712.58337536873 234888.86703802238 192962.2210207495 208209.32847055627 213232.30387016598 166424.70025715436 189059.73080181613 216831.45427539173 171724.62711352741 225378.82221809827 0.59771624525133 1.0421958226879067 0.8561683796271713 0.9238194006936147 0.9461062125163733 0.7384220869523658 0.8388531315460674 0.9620755496963451 0.7619377252195866 1.0 17.781992433086494 -12.000649191515077 2.261843525380629 2.6612676408558755 0.8620448321226671 0.11204313101809438 0.1221019849280431 6213519.647490321 729164.3983356705 53231879.333932765 0.028599636260398825 9.985062979798834e-13 12.000649191515077 -1.7992228087332083 RDS(ph)QGTYSSR ddPTM_PC-9_AZD4547_30min_R2 3 RDSQGTYSSR 10 1 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RDS(0.612)QGT(0.182)YS(0.182)S(0.024)R;RDS(0.751)QGT(0.125)YS(0.082)S(0.043)R;RDS(0.721)QGT(0.211)YS(0.062)S(0.007)R 132.86 0.00019447 5182320.0 19412.800000000003 23286.4 27095.7 36188.7 31407.8 32313.1 24531.9 32701.3 32197.7 36570.0 True False 25585.666588675816 30813.27340962876 26736.393313984136 27845.95432484148 27047.369108090938 30292.55674884893 26715.191575412555 27648.06548611724 33899.60468909266 35289.69543104169 0.7250180619629273 0.8731521491830343 0.7576260715037552 0.7890675729762033 0.7664381564568392 0.858396661655596 0.7570252803007534 0.7834600199410425 0.9606091601253585 1.0 15.106959358490496 -8.320284919210406 4.1674740210518895 0.9945225975467542 0.7907062771881412 0.7578984570033187 0.04345785317361755 0.09926203148507827 3.362562138809794 0.03811616934016975 0.01032604665527925 4.7831618968208885e-09 8.320284919210406 -0.20381632035861297 RDS(ph)QGTYSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RDSQGTYSSR 10 1 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RDS(0.389)QGT(0.389)Y(0.001)S(0.111)S(0.11)R;RDS(0.785)QGT(0.207)YS(0.006)S(0.001)R;RDS(0.998)QGT(0.001)YSSR;RDS(0.914)QGT(0.084)YS(0.001)SR 120.55 0.0010232999999999998 7861200.0 20958.2 29644.1 31027.399999999998 29858.000000000004 42728.1 33822.3 32328.9 33147.1 31953.800000000003 32330.4 True False 24506.009316681437 32586.970336968217 31767.21088806977 28185.153060942077 34355.83553123231 32048.599047243737 29266.47255103294 32277.02374725554 32421.06387434954 38191.645592694425 0.641658900431594 0.8532486576907723 0.831784291959036 0.7379926322507961 0.8995641585500087 0.8391520854857908 0.7663056172848243 0.8451330977324978 0.8489046065234559 1.0 15.220969463355694 -14.522878745279794 0.1152179412535631 1.5991862463748587 0.7133953868836302 0.5004765798272832 0.06431847505611471 145.09403555013193 1.0931153071621886 20.450779646928194 0.6987061158927562 3.000000000003756e-15 14.522878745279794 -0.8857908594912285 RDS(ph)QGTYSSR ddPTM_PC-9_Lapatinib_30min_R1 2 RDSQGTYSSR 10 1 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RDS(1)QGTYSSR;RDS(0.999)QGT(0.001)YSSR 112.64 0.001953 8531800.0 5676.1 7962.2 10042.7 8137.9 11157.4 9017.8 9364.2 13529.6 10421.3 9720.8 True False 5595.157773130743 7943.76401509611 9217.02797194307 8736.388313238589 10501.143668292396 8632.12971551853 9849.0324566175 14158.234608233111 9247.54345284596 11401.027327848184 0.4907590879520124 0.6967586154006181 0.8084383719903494 0.7662807975119102 0.9210699497791984 0.7571361305690114 0.8638723663577426 1.2418384941197504 0.8111149273590356 1.0 13.476876208677554 -4.23501369336115 0.3442332596547139 1.0079595254429772 3.762075606720844e-11 0.569546603307025 0.12285746903507791 7.359323016151175 0.5238156170136548 0.11687015266723623 3.316970502824755 5.820848642705196e-05 4.23501369336115 -1.0079595254053564 RDS(ph)SDDWEIPDGQITVGQR ddPTM_PC-9_AZD4547_30min_R2 5 RDSSDDWEIPDGQITVGQR 19 1 H7C560;P15056;A0A2R8Y679;A0A2R8Y492;A0A2R8YDP5;A0A2R8Y8E0;A0A2U3TZI2 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 RDS(0.95)S(0.05)DDWEIPDGQITVGQR;RDS(0.845)S(0.097)DDWEIPDGQIT(0.058)VGQR;RDS(0.5)S(0.5)DDWEIPDGQITVGQR;RDS(0.5)S(0.5)DDWEIPDGQITVGQR;RDS(0.971)S(0.029)DDWEIPDGQITVGQR 229.48 2.4539000000000003e-35 58411300.0 72012.7 78887.1 98513.8 139877.5 115190.6 98975.6 105782.6 128961.0 97043.4 99322.4 True False 94911.24064278897 104385.81235367953 97207.44264422666 107630.90346083221 99198.37352448938 92786.64008564268 115197.04647195048 109033.04067896878 102172.91600597232 95845.15300738592 0.9902560292795924 1.089108933298228 1.0142134431851317 1.1229665776895164 1.0349858121343398 0.9680890183199191 1.201907898911417 1.1375957704461759 1.066020688579826 1.0 16.548417854645592 -7.253819751078186 24.989621266534453 1.1128474046154622 1.0418242867495602 0.18548203694719656 0.06418469135969053 913.7452142895849 2996758.5794400023 0.02433812049265884 0.018468294606882058 5.574170504546611e-08 7.253819751078186 -0.07102311786590199 RDS(ph)SDDWEIPDGQITVGQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RDSSDDWEIPDGQITVGQR 19 1 H7C560;P15056;A0A2R8Y679;A0A2R8Y492;A0A2R8YDP5;A0A2R8Y8E0;A0A2U3TZI2 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 RDS(0.5)S(0.5)DDWEIPDGQITVGQR;RDS(0.774)S(0.226)DDWEIPDGQITVGQR;RDS(0.939)S(0.053)DDWEIPDGQIT(0.007)VGQR;RDS(0.907)S(0.093)DDWEIPDGQITVGQR;RDS(0.991)S(0.009)DDWEIPDGQITVGQR 145.43 3.7946e-05 29870700.0 32809.0 32665.6 34793.6 44107.4 46807.200000000004 36950.1 35116.700000000004 37375.399999999994 31058.700000000004 31350.1 True False 38362.91569271224 35908.42488857039 35623.21137946279 41636.205376120175 37635.66516829667 35012.371709066516 31790.191953108766 36394.33535250968 31512.87473021237 37033.62496274493 1.0358941564943898 0.9696167989143254 0.9619153246623579 1.1242811206843875 1.016256583203977 0.9454211340177541 0.8584142650115686 0.9827375902067821 0.8509260101303526 1.0 15.176548151306278 -6.826664618786519 4.223144142353491 0.9195610868863909 1.021430683334098 0.38320743462326023 0.060037557037923864 0.22784495207653013 8.022817542612376 0.021448318355158882 0.01920589810129793 1.490511671755639e-07 6.826664618786519 0.1018695964477071 RDS(ph)SDDWEIPDGQITVGQR ddPTM_PC-9_Lapatinib_30min_R1 6 RDSSDDWEIPDGQITVGQR 19 1 H7C560;P15056;A0A2R8Y679;A0A2R8Y492;A0A2R8YDP5;A0A2R8Y8E0;A0A2U3TZI2 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 RDS(0.738)S(0.262)DDWEIPDGQITVGQR;RDS(0.933)S(0.067)DDWEIPDGQITVGQR;RDS(0.789)S(0.211)DDWEIPDGQITVGQR;RDS(0.5)S(0.5)DDWEIPDGQITVGQR;RDS(0.5)S(0.5)DDWEIPDGQITVGQR;RDS(0.5)S(0.5)DDWEIPDGQITVGQR 231.42 1.0034e-35 55926400.0 89157.0 77130.7 81022.5 73047.29999999999 87238.5 77406.7 70715.0 79367.6 92686.4 66876.6 True False 87885.60483060883 76952.10860304617 74361.14280589453 78419.44212064956 82107.30294749007 74096.19588483096 74376.27668884759 83055.30844166892 82247.08160093857 78436.13120253182 1.1204734792907787 0.9810798597950514 0.9480470500754918 0.9997872271155347 1.046804599980573 0.9446691817767681 0.9482399953766054 1.0588909367190718 1.048586669688825 1.0 16.259230757091615 -7.788170918668748 24.99971800267016 1.0403041069782724 0.9956804362673077 0.09280447193909436 0.052514008390477256 499.45382372220894 467089.6680827895 0.029030502707937875 0.013952281679244812 1.628654941560543e-08 7.788170918668748 -0.044623670710964625 RDS(ph)SDTTPLLNGSSQDR ddPTM_PC-9_AZD4547_30min_R2 4 RDSSDTTPLLNGSSQDR 17 1 B4DQA8;E9PCW1 B4DQA8 GOSR1 Golgi SNAP receptor complex member 1 1 RDS(0.77)S(0.229)DTTPLLNGSSQDR;RDS(0.712)S(0.288)DTTPLLNGSSQDR;RDS(0.784)S(0.215)DT(0.001)TPLLNGSSQDR;RDS(0.712)S(0.286)DT(0.001)T(0.001)PLLNGSSQDR 214.46 4.298999999999999e-22 53136000.0 63594.0 80380.0 97755.0 94421.0 73634.0 64919.1 68637.0 76134.0 76504.0 60258.7 True False 83815.56916262735 106361.26308342902 96458.70482801777 72653.69723990795 63411.19011535879 60859.6984143954 74745.5600325124 64369.23968527394 80547.84525398842 58149.061254320804 1.441391612429502 1.8291140181652679 1.6588179197966044 1.2494388675020849 1.0904937886791246 1.0466153210663085 1.2854130130425516 1.106969541670648 1.38519596905794 1.0 15.82746828088392 -5.809085285247405 4.224093169607357 1.1607052179208202 1.6662506962788928 0.7166908668432679 0.13810431453970848 0.10237236613461613 3.823125469762248 0.03795096833294821 0.060462803037771476 1.55208218750034e-06 5.809085285247405 0.5055454783580726 RDS(ph)SDTTPLLNGSSQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RDSSDTTPLLNGSSQDR 17 1 B4DQA8;E9PCW1 B4DQA8 GOSR1 Golgi SNAP receptor complex member 1 1 RDS(0.765)S(0.213)DT(0.017)T(0.005)PLLNGSSQDR;RDS(0.969)S(0.031)DTTPLLNGSSQDR;RDS(0.72)S(0.224)DT(0.042)T(0.013)PLLNGSSQDR;RDS(0.758)S(0.239)DT(0.002)T(0.001)PLLNGSSQDR 228.26 5.266899999999999e-29 40002900.0 78885.0 86786.0 88479.0 74876.0 92536.0 62158.0 69771.0 61215.0 58801.0 55434.8 True False 92238.67245023047 95401.54053130734 90588.67491847611 70680.94047126714 74404.23507523428 58898.325057094764 63161.78578170358 59608.1711126538 59660.853384437185 65484.690418364684 1.4085532337549669 1.456852585265528 1.383356542418214 1.07935060881719 1.1362080907748808 0.8994212949745759 0.964527515945778 0.9102611729830693 0.9110656705144284 1.0 15.99887003980023 -5.934959571553597 1.1259535470173758 0.9348253337162111 1.4673877019184252 0.9152217145279828 0.06125736056542201 0.12819467879721363 0.32783320432567437 0.02272214811506444 0.049493199054123665 1.161556738052378e-06 5.934959571553597 0.532562368202214 RDS(ph)SDTTPLLNGSSQDR ddPTM_PC-9_Lapatinib_30min_R1 4 RDSSDTTPLLNGSSQDR 17 1 B4DQA8;E9PCW1 B4DQA8 GOSR1 Golgi SNAP receptor complex member 1 1 RDS(0.97)S(0.029)DT(0.001)TPLLNGSSQDR;RDS(0.955)S(0.045)DTTPLLNGSSQDR;RDS(0.712)S(0.283)DT(0.004)T(0.001)PLLNGSSQDR;RDS(0.856)S(0.144)DTTPLLNGSSQDR 269.99 1.4657999999999997e-69 58981100.0 79691.0 125315.0 76632.6 52471.1 67866.0 63494.6 66680.0 61905.0 88670.0 39399.4 True False 78554.59172646039 125024.84081683072 70332.16343839059 56329.99973245836 63874.25530968967 60779.08397114185 70132.36413225425 64781.33229531327 78683.05086350554 46209.533793599454 1.699965034863457 2.7056070588218764 1.522027115714645 1.2190125090649737 1.3822743937428987 1.3152931653156053 1.5177033476578459 1.4019040439721169 1.7027449620018464 1.0 15.495902913826566 -5.41887339726351 6.856003316534429 1.3837191540856904 2.1969161340053462 0.5758165800048466 0.2839047266643323 0.15448687400686034 8.807077766043397 0.06864717885793564 0.14395546479543628 3.811769254468855e-06 5.41887339726351 0.8131969799196559 RDS(ph)SESQLASTESDKPTTGR ddPTM_PC-9_AZD4547_30min_R2 1 RDSSESQLASTESDKPTTGR 20 2 A0A087WVF1;Q96B23-2;Q96B23;K7EQH1 A0A087WVF1 C18orf25 Uncharacterized protein C18orf25 1 RDS(0.876)S(0.119)ES(0.005)QLASTESDKPTTGR 148.97 0.00036528 52906000.0 7876.0 9495.8 8082.4 17602.0 11309.0 9411.9 10583.0 13440.0 9641.9 10448.0 True False 10380.404169023052 12565.131649510136 7975.22209505365 13544.13084818908 9738.940557549411 8823.372405138829 11524.86649801242 11363.156820475519 10151.55114967102 10082.218700123702 1.029575381944025 1.2462665235932613 0.7910185577462032 1.3433680870285925 0.9659521229617763 0.87514193726333 1.1430883261708078 1.1270492297827364 1.0068767055753778 1.0 13.299525533808197 RDS(ph)SESQLASTESDKPTTGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RDSSESQLASTESDKPTTGR 20 2 A0A087WVF1;Q96B23-2;Q96B23;K7EQH1 A0A087WVF1 C18orf25 Uncharacterized protein C18orf25 1 RDS(0.952)S(0.043)ES(0.005)QLASTESDKPTTGR;RDS(0.886)S(0.113)ESQLASTESDKPTTGR 120.66 3.1581e-05 62918000.0 20343.2 18083.9 19179.4 29352.0 26616.0 30005.0 25054.0 31353.0 24947.0 16025.1 True False 23786.90196348514 19879.150079668463 19636.709634279556 27707.502600467946 21400.78586455467 28431.484979216308 22680.70374474785 30530.016971249446 25311.802679912806 18930.323775378205 1.2565501914142463 1.05012203254148 1.0373150436983076 1.4636570895055587 1.1305028967539203 1.5019016746135014 1.1981149405509688 1.6127572530459529 1.3371035266092328 1.0 14.20841146598134 -5.753510568731147 24.990531677017533 1.3406412084738764 1.1082083574844872 0.20887045975971297 0.180585453730404 236.4458127209691 745236.41822556 0.04643046119289093 0.07860488141695868 1.7639628372079383e-06 5.753510568731147 -0.23243285098938915 RDS(ph)SESQLASTESDKPTTGR ddPTM_PC-9_Lapatinib_30min_R1 1 RDSSESQLASTESDKPTTGR 20 2 A0A087WVF1;Q96B23-2;Q96B23;K7EQH1 A0A087WVF1 C18orf25 Uncharacterized protein C18orf25 1 RDS(0.939)S(0.056)ES(0.005)QLASTESDKPTTGR 147.03 0.00049453 56034000.0 19766.0 17158.0 20704.0 13131.0 23482.0 17246.0 23753.0 19710.0 23235.0 26892.0 True False 19484.13321535954 17118.271705184383 19001.797039751185 14096.697543731903 22100.834927388278 16508.42878238956 24982.814115678375 20625.79855489257 20618.02962460305 31540.246368662403 0.6177546296758951 0.5427437536503414 0.6024619090683735 0.44694316521693467 0.7007185254376171 0.5234083649641976 0.7920931822682487 0.6539517261154258 0.6537054081190883 1.0 14.944906308969543 -11.954646917260629 0.19691515934125742 1.577829063644942 0.5212251886278022 0.6860755164965615 0.082581282285587 23.32517011813739 0.5719864391315317 6.07766903286431 0.21996685363658106 1.1100769444399075e-12 11.954646917260629 -1.0566038750171396 RDS(ph)STSTVSSAYTVSR ddPTM_PC-9_AZD4547_30min_R2 1 RDSSTSTVSSAYTVSR 16 1 P10070;P10070-4;P10070-3;P10070-2;P10070-1 P10070 GLI2 Zinc finger protein GLI2 1 RDS(0.948)S(0.048)T(0.003)S(0.001)TVSSAYTVSR 107.62 0.001864 0.0 3386.5 1582.5 5118.9 5713.8 5478.7 4311.7 4580.0 6979.0 5022.2 3571.8 True False 4463.336556424147 2094.0121775258303 5051.020041370158 4396.571687330007 4718.077074245816 4042.088717393627 4987.611127364351 5900.555911465669 5287.663238975491 3446.752369171306 1.2949397224893344 0.6075319469583156 1.4654432637945969 1.2755693523718572 1.3688471259048332 1.1727238526176618 1.4470465508270645 1.7119175616565472 1.5341001245896848 1.0 11.75102193712367 -5.286170293358612 24.946202661728186 1.3893945924013813 0.9512357395533352 0.32532541825197325 0.24130592138211485 699.7816414783849 705872.4383874953 0.06193464601661495 0.12901670928779801 5.174039103609618e-06 5.286170293358612 -0.4381588528480461 RDS(ph)STSTVSSAYTVSR ddPTM_PC-9_Lapatinib_30min_R1 1 RDSSTSTVSSAYTVSR 16 1 P10070;P10070-4;P10070-3;P10070-2;P10070-1 P10070 GLI2 Zinc finger protein GLI2 1 RDS(0.995)S(0.005)TSTVSSAYTVSR 186.17 5.4645e-39 0.0 10541.0 7556.2 8140.1 7652.7 4941.9 4899.5 5167.7 5256.1 6778.1 6995.7 True False 10390.683407017348 7538.704083151541 7470.852399694681 8215.505086658835 4651.227158149223 4689.959806292334 5435.258220249702 5500.31759433642 6014.679001442738 8204.897423815688 1.2664001595994554 0.9188054028889574 0.9105357463713861 1.0012928452721854 0.5668842543538064 0.5716049286221628 0.6624407277138189 0.6703700619548388 0.7330596216820967 1.0 13.002269582194193 -4.710302617106548 0.7124283076550294 0.6913629656533421 1.5858986257035226 0.5446474785852102 0.14504420105121965 2.437582841504262 0.8750026983692374 0.06211861224366872 1.8035481542075955 1.948486418092825e-05 4.710302617106548 0.8945356600501805 RDS(ph)YYDR ddPTM_PC-9_Lapatinib_30min_R1 1 RDSYYDR 7 1 Q13595;Q13595-4;Q13595-3 Q13595 TRA2A Transformer-2 protein homolog alpha 1 RDS(1)YYDR 102.06 0.005041899999999999 3151000.0 7068.3 13505.0 10354.0 9701.5 13090.0 14222.0 16359.0 15533.0 13837.0 15435.0 True False 6967.504745832533 13473.73000224472 9502.734087595809 10414.980673255275 12320.071935930177 13613.758213101251 17205.98897479824 16254.71988600438 12278.531349930381 18102.91918415529 0.3848829393179246 0.7442849335613064 0.5249282721160875 0.5753205086597891 0.6805571969140429 0.7520200512753099 0.9504538356365148 0.8979060073488834 0.6782625070036911 1.0 14.14393473724048 -6.735242720513953 1.7744135709398696 0.872142359807396 0.5684578431588917 0.6117277901726632 0.11478648503001866 0.24694504796334446 1.607123656757434 0.046002108934273214 0.042852730865047414 1.8397435097076554e-07 6.735242720513953 -0.30368451664850427 RDSFDDR ddPTM_PC-9_AZD4547_30min_R2 1 RDSFDDR 7 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 0 84.916 0.024693 0.0 6967.9 6974.4 7021.3 10262.0 9059.1 10934.0 8226.0 12520.0 9132.0 7884.7 False True 9183.547258676454 9228.73840817451 6928.192974364077 7896.254446319529 7801.400336448486 10250.295251520723 8958.098064126449 10585.321680978672 9614.698876652501 7608.659052915898 1.2069863026858858 1.212925739475439 0.9105668852002189 1.037798433522056 1.0253318334008832 1.347188141856936 1.1773556945876553 1.3912203986748513 1.2636522164793045 1.0 12.893426500786056 -6.753424605747987 24.999947716587727 1.256676595071882 1.0745621324620005 0.26401560876935637 0.12878977028861854 221.00940194112303 689379.0700983155 0.0428805074101899 0.0421620351491992 1.7643120254249767e-07 6.753424605747987 -0.1821144626098814 RDSFDDR ddPTM_PC-9_Lapatinib_30min_R1 2 RDSFDDR 7 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 0 ; 85.212 0.012299 4799600.0 11889.2 20645.3 19201.1 17864.2 22376.0 17047.1 20079.2 20354.0 20745.5 18273.8 False True 11719.657827787747 20597.49707629344 17622.459676389415 19177.99286122424 21059.887672908615 16318.035271731012 21118.80272771984 21299.72114593016 18408.92333020025 21432.40198169206 0.5468196162893403 0.9610447346913421 0.8222344696335406 0.8948130441751897 0.9826191059172158 0.7613722104349373 0.985367983754686 0.9938093343025557 0.8589295472306595 1.0 14.387505924985485 -4.756870516019521 24.999179615719623 0.9131496182269452 0.5468190671599161 0.6698146176745179 0.07807845026530066 81.81856199266215 447626.87422589445 0.01881697595437935 0.1466928360315287 1.7503684794924096e-05 4.756870516019521 -0.36633055106702905 RDSFDDRGPS(ph)LNPVLDYDHGSR ddPTM_PC-9_AZD4547_30min_R2 4 RDSFDDRGPSLNPVLDYDHGSR 22 2 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 1 RDS(0.107)FDDRGPS(0.893)LNPVLDYDHGSR;RDS(0.094)FDDRGPS(0.906)LNPVLDYDHGSR;RDS(0.378)FDDRGPS(0.622)LNPVLDYDHGSR;RDS(0.354)FDDRGPS(0.646)LNPVLDYDHGSR 85.166 7.3382e-05 221962300.0 48365.4 44322.4 263211.3 780839.0 430258.0 330045.4 122600.40000000001 415993.89999999997 181786.2 315307.10000000003 True False 63744.59113718483 58648.74902822806 259720.94618279202 600828.6323922907 370524.10349368525 309407.60896344116 133511.59809155433 351711.6013438393 191395.04740811745 304268.2944010125 0.20950126026989918 0.19275340253142362 0.853591882434162 1.9746672375940182 1.2177545617202905 1.016890733135853 0.4387956305286012 1.1559258976891578 0.6290338195930038 1.0 18.21498448330233 -5.328064853572061 4.44410107170742 1.0690344461941332 0.19559092898943561 0.43735018085394617 0.38252400646965246 0.19646688918723101 7.623735036239387 0.10881164640032943 0.24645298430031382 4.6982394414897904e-06 5.328064853572061 -0.8734435172046976 RDSFDDRGPS(ph)LNPVLDYDHGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RDSFDDRGPSLNPVLDYDHGSR 22 2 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 1 RDS(0.152)FDDRGPS(0.848)LNPVLDYDHGSR;RDS(0.204)FDDRGPS(0.796)LNPVLDYDHGSR 67.214 0.00081659 20247500.0 9169.2 15451.7 57998.0 50568.0 57386.0 73326.0 51000.0 52629.0 56630.0 35381.0 True False 10721.36446004502 16985.642659272235 59380.892278639854 47734.83890366796 46141.625248847864 69480.6554769544 46168.91079197496 51247.54451503482 57458.10661656566 41795.29522415808 0.25652084528997343 0.4064008297626373 1.4207554213976967 1.142110341550519 1.1039908918307524 1.6624037491376282 1.104643729500178 1.2261558206535468 1.374750586361556 1.0 15.351052930975484 -5.218289374996113 6.25988352393851 1.2622943673142555 0.31587894148397855 0.7993367521582714 0.18501097835664615 0.08315045380118254 8.736181918057529 0.04577114847945154 0.1218366499532828 6.049376640879842e-06 5.218289374996113 -0.9464154258302769 RDSFDDRGPS(ph)LNPVLDYDHGSR ddPTM_PC-9_Lapatinib_30min_R1 3 RDSFDDRGPSLNPVLDYDHGSR 22 2 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 1 RDS(0.043)FDDRGPS(0.957)LNPVLDYDHGSR;RDS(0.279)FDDRGPS(0.721)LNPVLDYDHGSR;RDS(0.072)FDDRGPS(0.928)LNPVLDYDHGSR 78.418 0.00020855 65415400.0 63723.7 34899.0 155127.0 41815.2 121218.0 149544.0 93248.0 97780.0 224272.0 85442.0 True False 62814.98835250466 34818.19350968817 142373.05686753668 44890.42929941803 114088.1955637574 143148.35172409037 98075.92517403186 102323.21576343948 199012.12567114158 100210.53585569133 0.6268301812392431 0.34745042736652243 1.4207394028165032 0.44796117410311737 1.1384850364242205 1.4284760629384505 0.9786987399734752 1.0210824130387899 1.985940140642796 1.0 16.612674671868987 -5.397054556561105 0.47950656899078076 1.3315799117791862 0.2276767955734957 0.31555594981696555 0.38865464908438796 3.375232371790307 0.9177249594461864 0.2813142330222375 1.980854653621525 4.008163634623691e-06 5.397054556561105 -1.1039031162056905 RDSFDNCS(ph)LGESSK ddPTM_PC-9_AZD4547_30min_R2 1 RDSFDNCSLGESSK 14 1 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 RDS(0.202)FDNCS(0.798)LGESSK 193.54 2.3815999999999998e-07 7534300.0 18598.0 17518.0 17892.0 24527.0 21743.0 20801.0 21880.0 22726.0 16943.0 18790.0 True False 24511.777137568675 23180.35091683887 17654.740389574883 18872.679088372548 18724.359761499414 19500.310181715977 23827.27761282357 19214.218891527264 17838.572390179957 18132.167819230886 1.3518393047063908 1.2784103449701092 0.9736695890741952 1.0408396434736435 1.0326597430694664 1.0754538771163393 1.3140887427455024 1.0596757697746853 0.9838080348705165 1.0 14.146263798569183 -5.119180662077572 5.040831228989898 1.0707025942299022 1.3349148583675827 0.5544719290393985 0.09190644438981962 0.16935226049644767 6.135536819538322 0.025138053647254677 0.0721199462579237 7.600100547363849e-06 5.119180662077572 0.2642122641376805 RDSFDNCS(ph)LGESSK ddPTM_PC-9_Lapatinib_30min_R1 1 RDSFDNCSLGESSK 14 1 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 RDS(0.274)FDNCS(0.72)LGES(0.004)S(0.001)K 119.77 0.00014147 10957000.0 19931.0 26781.0 35043.0 33982.0 25953.0 35492.0 27962.0 30970.0 36731.0 42243.0 True False 19646.780285102242 26718.990239919724 32161.899809891842 36481.14964062886 24426.495565561196 33974.08989589299 29409.73554088324 32408.979261543554 32593.96798542262 49544.646264740666 0.3965469887527328 0.5392911697693313 0.6491498523984908 0.7363287941484673 0.49301988019126797 0.6857267627737865 0.5936006765238165 0.6541368584683586 0.6578706367436253 1.0 15.596441549481767 -14.522878745274507 0.1578325298952781 2.4502476552940253 0.49624510595438526 0.6887605762924307 0.08547490163492204 81.22820219822714 0.7394595389061835 36.88845802293437 0.3887880979815428 3.0000000000402736e-15 14.522878745274507 -1.95400254933964 RDSFIGT(ph)PYWMAPEVVMCETSK ddPTM_PC-9_AZD4547_30min_R2 2 RDSFIGTPYWMAPEVVMCETSK 22 1 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 RDS(0.294)FIGT(0.373)PY(0.333)WMAPEVVMCETSK;RDS(0.055)FIGT(0.687)PY(0.257)WMAPEVVMCETSK 73.796 0.00047803 22158600.0 46635.7 55614.5 81977.6 90227.0 85635.0 81736.7 64683.0 79525.1 64451.0 83815.2 True False 61464.88251717986 73590.7995241771 80890.52346078762 69426.559143254 73746.0584176978 76625.69122781903 70439.66169242526 67236.32309999975 67857.74828067575 80880.85535936146 0.7599435273537284 0.9098667317155099 1.0001195351036187 0.8583806246210562 0.9117863317596844 0.9473897239014557 0.8709064880614211 0.8313008412344585 0.8389840584545899 1.0 16.30351063416159 RDSFIGT(ph)PYWMAPEVVMCETSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RDSFIGTPYWMAPEVVMCETSK 22 1 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 RDS(0.295)FIGT(0.373)PY(0.332)WMAPEVVMCETSK 44.848 0.016624 12190000.0 10492.0 14093.0 14272.0 13774.0 16946.0 16597.0 17434.0 11793.0 13779.0 12976.0 True False 12268.088373554112 15492.059902607707 14612.29860686141 13002.287435910517 13625.552947878845 15726.624102651336 15782.525308770424 11483.446245716348 13980.491807693059 15328.44608204052 0.8003478178996853 1.0106738686812413 0.9532798385859751 0.8482456320960392 0.888906342818607 1.0259764113387422 1.0296233045606575 0.7491591896696468 0.9120619097896177 1.0 13.90392383105607 -4.734953889178273 24.12834529130841 0.9296553088610909 0.8003468229300222 0.181748891074211 0.08515765076162594 3374.4585918188577 3073887.7948470702 0.022001811677867397 1.6699725126493328 1.8409674541382812e-05 4.734953889178273 -0.1293084859310687 RDSFIGT(ph)PYWMAPEVVMCETSK ddPTM_PC-9_Lapatinib_30min_R1 3 RDSFIGTPYWMAPEVVMCETSK 22 1 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 RDS(0.095)FIGT(0.478)PY(0.427)WMAPEVVMCETSK;RDS(0.068)FIGT(0.911)PY(0.021)WMAPEVVMCETSK;RDS(0.431)FIGT(0.456)PY(0.113)WMAPEVVMCETSK 97.662 0.00060364 15842600.0 46248.0 61523.0 86236.0 69531.0 73668.0 70275.0 58972.0 56682.0 93983.0 51204.0 True False 45588.49503915552 61380.547273461874 79146.00896058655 74644.54168861647 69334.99307686048 67269.50206902614 62025.281607787896 59315.65264781436 83397.64485513525 60054.543174958686 0.7591181720647046 1.0220799964232532 1.3179021065901397 1.2429457913142776 1.1545336857340631 1.12014010119181 1.0328158092400737 0.987696342556604 1.3886983473035572 1.0 15.87398577066026 -4.859365184959256 3.5072792412111458 1.1535717927851636 0.7423226892842533 0.4776179211521636 0.12601164240160417 0.22396981235885213 4.613220331269361 0.03225662027599763 0.214877468109077 1.3824034692769652e-05 4.859365184959256 -0.4112491035009104 RDSFIGTPY(ph)WMAPEVVMCETSK ddPTM_PC-9_AZD4547_30min_R2 1 RDSFIGTPYWMAPEVVMCETSK 22 1 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 RDS(0.083)FIGT(0.442)PY(0.475)WMAPEVVMCETSK 51.431000000000004 0.015988 23293000.0 30826.0 23753.0 40426.0 56207.0 60573.0 44776.0 33609.0 49361.0 41529.0 52018.0 True False 40628.026779368294 31430.692734768418 39889.92482612085 43249.344539493424 52163.48451608812 41976.1496416766 36600.1358907398 41733.39165293839 43724.13815686616 50196.86565304695 0.8093737776414766 0.6261485119810578 0.7946696333957164 0.861594523419575 1.039178120734353 0.8362304915970117 0.7291318972725177 0.8313943731346336 0.8710531541766114 1.0 15.615309663088464 -1.5228787452835884 0.043793775927950244 1.3213874631625033 4.9231877318881757e-11 0.2768007325192129 0.0961407349099595 1004.4715791482389 3.3518821233284157 26.19790541199565 94.71330417753865 0.029999999999775442 1.5228787452835884 -1.3213874631132714 RDSGDNS(ph)APSGQER ddPTM_PC-9_Lapatinib_30min_R1 1 RDSGDNSAPSGQER 14 1 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 RDS(0.254)GDNS(0.742)APS(0.004)GQER 73.415 0.030164999999999997 4869500.0 778.24 768.75 2567.2 995.83 2065.8 2589.9 2726.1 1152.9 2321.7 2468.9 True False 767.1421548882626 766.9700066068596 2356.1347256785753 1069.0666601914966 1944.2937055190648 2479.136014351776 2867.2441190902573 1206.4679428683744 2060.2056974151465 2895.6460753975393 0.2649295303753387 0.2648700796424381 0.8136818742100947 0.369197972526641 0.6714541953308764 0.8561598861875475 0.9901914959329473 0.41664896587983047 0.711483946508312 1.0 11.499669562334487 -4.993888016771368 0.6751841709785628 0.7624388572721262 2.0361838884176468e-16 0.44300653833238157 0.2029760285520097 2.608258019629626 1.0887890889135403 0.09647670766809376 1.4634196528513235 1.0141728574220116e-05 4.993888016771368 -0.762438857272126 RDSLAS(ph)LFPSEEEER ddPTM_PC-9_AZD4547_30min_R2 1 RDSLASLFPSEEEER 15 1 Q6P597;Q6P597-3;Q6P597-2;K7ENJ3;K7EL76 Q6P597 KLC3 Kinesin light chain 3 1 RDS(0.321)LAS(0.419)LFPS(0.261)EEEER 84.41 0.008982500000000001 2550600.0 4550.1 6610.8 5399.1 6092.9 6215.2 6042.9 4319.6 9212.2 6838.9 5136.7 True False 5996.937152040606 8747.611818760042 5327.50440629073 4688.276039366618 5352.326762161205 5665.036507720374 4704.036031825991 7788.666165296464 7200.3902921089375 4956.865696489798 1.209824417128617 1.7647465867301304 1.0747727964595448 0.9458146188400097 1.0797804681194918 1.1428666529601692 0.9489940458054273 1.5712885202461717 1.452609518391408 1.0 12.27521245498273 -5.285245197516421 24.932451864718296 1.154897279321391 1.4872855975082921 0.25036640262610754 0.23201200383577064 950.3137454721506 995287.0308605569 0.06340077491914436 0.13209116780009253 5.185072132474926e-06 5.285245197516421 0.3323883181869012 RDSQGTYS(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 2 RDSQGTYSSR 10 1 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RDS(0.057)QGT(0.023)YS(0.898)S(0.023)R;RDS(0.097)QGT(0.307)YS(0.575)S(0.022)R 88.338 0.0099475 0.0 8542.2 14173.7 15322.900000000001 14453.9 21868.9 18586.4 20660.9 20694.0 23501.0 19434.9 True False 8420.386661552378 14140.88166847953 14063.110310104485 15516.88802279693 20582.61429791166 17791.50299901458 21730.620307439898 21655.518787161192 20854.069903498865 22794.196569623557 0.36940923255762903 0.6203720155385615 0.6169601225974132 0.6807385369079139 0.9029760814356081 0.7805277516437775 0.9533400416665256 0.950045276700833 0.9148850603179328 1.0 14.476378938765414 -4.815219853556947 0.38527157653226285 0.9895219365577415 1.1610840787960405e-14 0.9078375880137305 0.05848743711139817 1.5824941810677866 0.18999360354990116 0.04950056571026282 0.7296780234473365 1.530312573097722e-05 4.815219853556947 -0.9895219365577298 down RDSS(ph)DDWEIPDGQITVGQR ddPTM_PC-9_AZD4547_30min_R2 1 RDSSDDWEIPDGQITVGQR 19 1 H7C560;P15056;A0A2R8Y679;A0A2R8Y492;A0A2R8YDP5;A0A2R8Y8E0;A0A2U3TZI2 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 RDS(0.415)S(0.585)DDWEIPDGQITVGQR 90.475 0.00045613 16372000.0 9416.2 7387.3 11454.0 15152.0 12365.0 11923.0 10082.0 13763.0 9740.2 13849.0 True False 12410.355730872894 9775.100258474924 11302.112476089349 11658.940496066405 10648.333185436248 11177.452925176654 10979.278468578028 11636.244592277115 10255.04708698759 13364.150725307521 0.9286303324439137 0.7314419344256528 0.8457037568939328 0.8724041456662127 0.7967833799772727 0.8363758502072305 0.8215470398569142 0.8707058780953216 0.7673549406748114 1.0 13.706080538618078 -10.94868800587558 3.5566219732194044 1.0015505734641486 0.8290530517331316 0.47857388455023264 0.05319120095710988 10490420.481766367 6692845.233977065 119541.69624154347 0.011841748986633214 1.1254131725978414e-11 10.94868800587558 -0.17249752173101696 RDSS(ph)DDWEIPDGQITVGQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RDSSDDWEIPDGQITVGQR 19 1 H7C560;P15056;A0A2R8Y679;A0A2R8Y492;A0A2R8YDP5;A0A2R8Y8E0;A0A2U3TZI2 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 RDS(0.248)S(0.752)DDWEIPDGQITVGQR;RDS(0.236)S(0.764)DDWEIPDGQITVGQR 144.95 9.196700000000001e-05 32396000.0 44205.0 46396.0 47679.0 51605.0 53013.0 49864.0 52352.0 48015.0 38135.0 34518.0 True False 51688.03341145247 51001.888259518004 48815.848183614406 48713.73915566735 42625.48320700473 47249.04405944485 47392.83956434264 46754.65712609772 38692.65223066802 40775.840155662336 1.2676141856092402 1.2507869381677383 1.1971757785310917 1.1946716234344155 1.045361249315314 1.1587509632927482 1.1622774511431235 1.1466264569316333 0.9489112200498698 1.0 15.315426982444192 -1.5228790527960223 0.12987607260172698 0.9392431079809787 2.077820010192854 0.668675864524565 0.05776272598798064 53.35215991851666 0.4707985718872003 0.32195243867808576 11.116838111479536 0.029999978757576574 1.5228790527960223 1.1385769022118755 RDSS(ph)ESQLASTESDKPTTGR ddPTM_PC-9_Lapatinib_30min_R1 1 RDSSESQLASTESDKPTTGR 20 2 A0A087WVF1;Q96B23-2;Q96B23;K7EQH1 A0A087WVF1 C18orf25 Uncharacterized protein C18orf25 1 RDS(0.221)S(0.651)ES(0.127)QLASTESDKPTTGR 99.01100000000001 0.0010608 55328000.0 10239.0 7841.3 11012.0 7947.2 9975.8 12081.0 9618.0 13309.0 13894.0 10570.0 True False 10092.989982397368 7823.143951618037 10106.635867549261 8531.663599082032 9389.04305717741 11564.323792186487 10115.972978764563 13927.384726893217 12329.111409693776 12397.010416360317 0.8141470921955235 0.6310508492671624 0.8152478321879562 0.6882033097127036 0.7573634886025992 0.9328316589074626 0.8160010066148309 1.1234470456291032 0.9945229531648263 1.0 13.597704631008039 -7.196787549436135 1.090046876003298 1.03851865306513 0.7303255182808849 0.6764087643834468 0.0825987323902393 0.27645526459087794 0.6478639352544552 0.052940607772024764 0.03178939890675598 6.356418025626896e-08 7.196787549436135 -0.30819313478424515 RDSVY(ph)S(ph)CVT(ph)LPYFHS(ph)FLYMK ddPTM_PC-9_Lapatinib_30min_R1 1 RDSVYSCVTLPYFHSFLYMK 20 1 E9PEW5;A0A0A0MQX1;Q9HD67-3;Q9HD67 E9PEW5 MYO10 Unconventional myosin-X 4 RDS(0.279)VY(0.853)S(0.867)CVT(0.989)LPY(0.273)FHS(0.369)FLY(0.369)MK 47.09 0.039329 0.0 6333.4 6836.2 6007.6 6316.3 7236.8 7322.4 5422.0 5858.1 6030.7 5341.7 True False 6243.084554596687 6820.37119891488 5513.6783180066295 6780.821772559119 6811.14565209622 7009.238021348099 5702.7246299502485 6130.28871204547 5351.459059913648 6265.005727632159 0.9965010130894554 1.0886456446214008 0.8800755430578846 1.0823328927940041 1.0871730926047332 1.118791957433249 0.910250505406254 0.9784969046408829 0.8541826284867926 1.0 12.61310011315938 -7.2809474870925275 24.899005758966265 0.9339405763616858 1.040853985538155 0.3378954231195185 0.07301567867986464 960.1759327448815 1225507.415758529 0.03073581864515144 0.02075786040922803 5.2366375178965916e-08 7.2809474870925275 0.10691340917646908 RDTQQGMY(ph)DAVLHVAT(ph)SLTTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RDTQQGMYDAVLHVATSLTTR 21 1 M0R045;M0QXC1 M0R045 PAPL 2 RDT(0.012)QQGMY(0.788)DAVLHVAT(0.889)S(0.271)LT(0.033)T(0.007)R 41.988 0.026948000000000003 1404500.0 3328.1 4846.4 3704.1 4706.3 3112.1 3914.4 4759.4 3280.5 2805.9 2292.3 True False 3891.48159702873 5327.518563258216 3792.4197918774744 4442.62126903047 2502.306345396778 3709.121973092629 4308.555176927953 3194.3903509770603 2846.9309792587233 2707.875844163185 1.4370974967027392 1.9674161113190105 1.4005146506447184 1.640629602205183 0.9240845922794019 1.3697533367667598 1.5911199127593039 1.179666474688105 1.0513521088477047 1.0 11.402945877667943 -4.468809137137807 0.18242656675452193 0.9285300737769745 2.472231897935939 0.39674961050448576 0.24015524415506653 20.20019490266915 0.5998034567580932 0.6642699308970408 7.33312389502693 3.397745632221719e-05 4.468809137137807 1.5437018241589642 RDTVSLY(ph)QRT(ph)LEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RDTVSLYQRTLEQR 14 2 Q96JK9 Q96JK9 MAML3 Mastermind-like protein 3 2 RDTVSLY(1)QRT(1)LEQR;RDTVSLY(1)QRT(1)LEQR 131.09 7.1967e-05 7877900.0 19460.2 22098.1 22696.7 20491.1 24231.0 19300.1 18404.2 20874.2 17994.7 18703.0 True False 22754.427503530074 24291.85332674486 23237.875405714087 19343.05010004254 19483.109493688913 18287.968780115738 16660.820941130703 20326.27436804309 18257.83844487221 22093.705847133457 1.0299054246928132 1.099492022516295 1.0517871273609394 0.8755004811722068 0.8818398157598692 0.8277456442414122 0.7540980701203803 0.9200029415020169 0.8263818922546698 1.0 14.431347806340046 -5.764076087649438 4.361524801529001 0.8583663722040362 1.0679034780687433 0.6574371596116786 0.06299781217242405 0.10827104901496432 4.892051389508533 0.017215695918880947 0.028507143462945753 1.7215669329849679e-06 5.764076087649438 0.20953710586470708 RDTVSLY(ph)QRT(ph)LEQR ddPTM_PC-9_Lapatinib_30min_R1 2 RDTVSLYQRTLEQR 14 2 Q96JK9 Q96JK9 MAML3 Mastermind-like protein 3 2 RDTVSLY(1)QRT(1)LEQR;RDTVSLY(1)QRT(1)LEQR 105.4 0.0040213 7504600.0 25716.3 21878.9 19854.7 15810.8 22345.8 18530.1 14500.6 14067.9 22859.1 15119.5 True False 25349.58084620815 21828.2407512856 18222.32320735837 16973.578975282646 21031.463977533116 17737.61081877285 15251.37011601928 14721.545991393872 20284.46744100554 17732.885429532616 1.4295237482327932 1.2309469227682777 1.0276005718172994 0.9571808853518328 1.1860147668076058 1.0002664760486393 0.8600613913976694 0.8301833364849008 1.1438898379856153 1.0 14.114139684888244 -1.5228793504576477 0.6298700297273351 0.9703712355119843 38.05681503325216 0.6358829268007167 0.1044872768136021 127.23112740038496 0.8853758997790696 0.04710252432652005 6547.72964253339 0.029999958195861542 1.5228793504576477 37.08644379774017 RDVQEIFR ddPTM_PC-9_AZD4547_30min_R2 4 RDVQEIFR 8 1 A0A140T9L4;A0A140T973;A0A140T9K1;A0A140T9X9;A0A140T996;F6S4E6;A0A0A0MT12;F6TRA5;F6UJC5;A0A140TA18;F6WLT2;A0A140T9X3;A0A0G2JJZ9;Q5STU3;Q13838;Q13838-2;K7EQN7;O00148-3;O00148-2;O00148 A0A140T9L4;K7EQN7 DDX39B;DDX39A Spliceosome RNA helicase DDX39B;ATP-dependent RNA helicase DDX39A 0 ;;; 152.11 0.00017202 16347300.0 42645.9 44993.6 56031.1 78528.3 70368.5 56110.7 48403.3 66630.9 53910.9 69549.2 False True 56206.40911017524 59536.90130219665 55288.0910039296 60424.81368514072 60599.048423725886 52602.089058853475 52711.09993038316 56334.625430760614 56760.5201127163 67114.30367712904 0.8374728788153851 0.8870970574114057 0.8237899817884943 0.9003269105767697 0.9029230000694562 0.7837686778649992 0.785392934775331 0.8393832960224561 0.8457291069542743 1.0 16.034332651860247 -8.688757194401365 15.24730879136832 1.000000000035762 0.8452773733947273 0.5739662793643427 0.040036458016965495 16608.795476217456 1526669.5536030543 0.041965423956797344 0.010835188596896283 2.047589084010932e-09 8.688757194401365 -0.15472262664103476 RDVQEIFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RDVQEIFR 8 1 A0A140T9L4;A0A140T973;A0A140T9K1;A0A140T9X9;A0A140T996;F6S4E6;A0A0A0MT12;F6TRA5;F6UJC5;A0A140TA18;F6WLT2;A0A140T9X3;A0A0G2JJZ9;Q5STU3;Q13838;Q13838-2;K7EQN7;O00148-3;O00148-2;O00148 A0A140T9L4;K7EQN7 DDX39B;DDX39A Spliceosome RNA helicase DDX39B;ATP-dependent RNA helicase DDX39A 0 ; 65.465 0.032718000000000004 7493900.0 19473.2 18203.6 24254.0 25755.0 28143.0 24927.0 25441.0 23782.1 22594.3 19189.9 False True 22769.628146768388 20010.73310459871 24832.307343807217 24312.03084883659 22628.581176215906 23619.784238524426 23031.044303110502 23157.84507421783 22924.69889328394 22668.876962835187 1.0044444717794525 0.8827403817756649 1.0954361517122748 1.0724850149698768 0.9982224180454398 1.041947701125566 1.0159764129854811 1.0215700192022872 1.0112851611867746 1.0 14.468425299949681 -5.2607808682954555 24.999867891266298 1.0328917923751526 0.9435924304542688 0.43722262484486885 0.04016512599666278 50.38552778863197 1912755.6171647012 0.010153055638214574 0.023825175182377006 5.485536785027734e-06 5.2607808682954555 -0.08929936192088384 RDVQEIFR ddPTM_PC-9_Lapatinib_30min_R1 3 RDVQEIFR 8 1 A0A140T9L4;A0A140T973;A0A140T9K1;A0A140T9X9;A0A140T996;F6S4E6;A0A0A0MT12;F6TRA5;F6UJC5;A0A140TA18;F6WLT2;A0A140T9X3;A0A0G2JJZ9;Q5STU3;Q13838;Q13838-2;K7EQN7;O00148-3;O00148-2;O00148 A0A140T9L4;K7EQN7 DDX39B;DDX39A Spliceosome RNA helicase DDX39B;ATP-dependent RNA helicase DDX39A 0 ;; 112.11 0.0023883000000000003 7198600.0 49311.0 44322.0 48818.0 44152.0 53550.0 47657.0 40301.0 42541.0 50887.0 39801.0 False True 48607.81609747011 44219.37513213555 44804.37248292957 47399.08536675433 50400.294283350726 45618.82120389303 42387.58858569253 44517.61016355584 45155.57019613409 46680.54981850114 1.0412862806128544 0.9472762275522698 0.9598081568690526 1.0153926110777813 1.0796851039525528 0.9772554389625611 0.9080353327135158 0.95366507756753 0.9673315839617072 1.0 15.510533933220108 -6.99815969250577 24.99997022198416 0.9518608398210356 1.0054881325404743 0.2554085834820574 0.04103746549316948 86.29700392276294 1172293.3653181144 0.015343276134369139 0.01344267827523162 1.004246455350708e-07 6.99815969250577 0.05362729271943867 RDVYLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 RDVYLSPR 8 1 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 RDVYLS(1)PR;RDVYLS(1)PR;RDVYLS(1)PR 100.93 0.0021736 83153000.0 121671.0 116022.0 155586.0 195647.0 166004.0 144576.0 127805.0 142201.0 138769.0 147655.0 True False 160359.84708598338 153523.84256613083 153522.82798191367 150543.60686601786 142957.21003761893 135535.63986499544 139179.3974089084 120227.10290390173 146104.04603747168 142485.64339268403 1.1254456467872966 1.0774688516724875 1.0774617310658565 1.0565528096829127 1.0033095730468458 0.9512231312418284 0.9767959360322096 0.8437839773973665 1.0253948577458818 1.0 17.1204570375766 -6.283150378836358 1.2616764152888604 0.9474638035980102 1.098320071404572 0.618747900519725 0.04662697672646162 0.27454204085775785 0.8926535921116887 0.018070270613935128 0.025447093841969894 5.21014273430529e-07 6.283150378836358 0.1508562678065618 RDVYLS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RDVYLSPR 8 1 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 RDVYLS(1)PR;RDVYLS(1)PR;RDVYLS(1)PR;RDVYLS(1)PR;RDVYLS(1)PR 99.215 0.0024149 100876400.0 276735.0 278095.0 310278.0 319745.0 351139.0 308180.0 293068.0 269192.0 281696.0 232355.0 True False 323580.76973460696 305702.4337341717 317676.20425586746 301830.72427727695 282335.833622402 292018.498280116 265306.47741142235 262125.99523250057 285815.2710835266 274479.12217883224 1.1788902819493257 1.11375477780418 1.15737838905245 1.0996491167755347 1.0286240766918908 1.0639005836292943 0.9665816303455183 0.9549942930148138 1.0413005871437773 1.0 18.06633689151952 -6.300770534221858 1.0056270988034925 0.9904453447822067 1.1562980810491261 0.8046269309769309 0.03211168030982186 0.22597845220645274 0.4837743111599978 0.014903324592972294 0.0221698838867689 5.002988052734558e-07 6.300770534221858 0.16585273626691943 RDVYLS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 RDVYLSPR 8 1 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 RDVYLS(1)PR;RDVYLS(1)PR 104.79 0.001766 63517000.0 143074.0 122273.0 151732.0 109257.0 151269.0 142276.0 118413.0 130270.0 124918.0 103000.0 True False 141033.73852344207 121989.88438093061 139257.1806624578 117292.1242506676 142371.65482629673 136191.18714155507 124543.84574074112 136322.81977401592 110848.41939514368 120803.41276112685 1.1674648530196583 1.0098215074614643 1.1527586636796503 0.9709338632890914 1.178540006215042 1.1273786396321068 1.0309629744236655 1.1284682829580046 0.9175934426151694 1.0 16.882301686583297 -8.260125066217686 24.996744271255228 0.9587967147846601 1.0923127354327704 0.38421760355637746 0.06926065790429745 112.53136852287307 2140342.817330654 0.04956898017689996 0.01633859092956718 5.4938264227460204e-09 8.260125066217686 0.1335160206481103 RDWGDHGR ddPTM_PC-9_AZD4547_30min_R2 1 RDWGDHGR 8 1 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 0 67.89699999999999 0.02852 2632900.0 3729.2 3501.5 5705.2 5724.2 5092.6 5753.2 5351.7 5281.9 3870.5 4649.5 False True 4915.008027821327 4633.291399435513 5629.545320288538 4404.574128008406 4385.580394674695 5393.451494517011 5827.990932383358 4465.703720987322 4075.0867282176423 4486.722420197659 1.0954562300746924 1.0326672714536678 1.2547121914532287 0.981690801325384 0.9774574809737152 1.2020916360320342 1.2989417188252557 0.9953153555665228 0.9082547005522391 1.0 12.131446216304662 -7.981503985163138 24.9663401140028 0.9533464733594292 1.116854607806782 0.31437990267118243 0.10434644775745422 276.9707531790987 373861.17144969816 0.05992461701040404 0.02877969069948483 1.0435085572652239e-08 7.981503985163138 0.1635081344473528 RDWGDHGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RDWGDHGR 8 1 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 0 ;;; 97.635 0.0036400999999999994 5332470.0 15434.7 16624.1 21484.800000000003 20976.699999999997 22316.399999999998 15776.3 18824.3 19328.6 13768.5 11889.2 False True 18047.489860779227 18274.430783150558 21997.07911355773 19801.443506378975 17943.661619617833 14948.963055411103 17041.126027870083 18821.24473034453 13969.838265057107 14044.617845144585 1.2850111024571942 1.301169671161133 1.5662283841466302 1.409895500519055 1.2776183601051987 1.0643908734461693 1.2133563344880496 1.3401037278384396 0.9946755703208165 1.0 13.777729748733192 -6.511954237786453 4.048920726823968 1.1496640341054216 1.3939728671894847 0.5188582917070721 0.1204526963833329 0.19776943776215442 7.467915346106684 0.04079176017931277 0.043608029082007616 3.0764209644178666e-07 6.511954237786453 0.24430883308406304 RDWGDHGR ddPTM_PC-9_Lapatinib_30min_R1 3 RDWGDHGR 8 1 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 0 ;; 85.86200000000001 0.0081678 5527980.0 8705.5 9923.1 16172.8 11028.0 11242.199999999999 11957.1 13320.4 12278.8 11712.2 11137.5 False True 8581.357973606822 9900.123671623449 14843.134812813361 11839.035908329563 10580.9558990156 11445.722706361488 14010.06513478223 12849.317873963217 10393.048701066326 13062.60203521409 0.656940933396979 0.7578982843490716 1.1363076646444041 0.9063305975650147 0.8100190046739171 0.8762207311763899 1.0725324936803535 0.9836721534747899 0.7956338770061894 1.0 13.67315468603464 -5.038347713634511 9.984662639534136 0.942933378874869 0.6818164930833677 0.4794335009656715 0.10241094035624308 0.4257641985769885 110.5860566022658 0.026695860797212322 0.07239889407522247 9.154872207183859e-06 5.038347713634511 -0.2611168857915014 RDY(ph)TPST(ph)NSLVS(ph)MAS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RDYTPSTNSLVSMASK 16 1 E9PQ85;A0A0G2JHK2;F8VVU2;A0A140T9M2;A0A0G2JP41;A0A0G2JM93;Q5SRN2 E9PQ85 C6orf10 Uncharacterized protein C6orf10 4 RDY(0.572)T(0.447)PS(0.471)T(0.512)NS(0.341)LVS(0.698)MAS(0.959)K 41.367 0.045274 0.0 0.0 2647.3 1523.1 3095.5 2463.7 2971.2 2349.9 1314.6 1271.9 953.89 True False 0.0 2910.1064486038017 1559.4164803889164 2922.0691707464057 1980.9556708184305 2815.385041501333 2127.300460197293 1280.093142933835 1290.4991313016044 1126.8227060109143 0.0 2.582577039919548 1.3839058017471402 2.593193370313664 1.7580012012992248 2.4985164271921083 1.8878750391249999 1.1360200110499337 1.145254816412179 1.0 10.138044824768452 -7.7683619366622185 7.346774320884313 1.1012702109489307 1.8826906597244053 0.1694711314144125 0.7208069385100355 0.21828770748451348 67.85184247064228 0.3555465641371126 0.18259718082708162 1.7046611493697037e-08 7.7683619366622185 0.7814204487754746 RDYDDMS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 6 RDYDDMSPR 9 1 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 RDYDDMS(1)PR;RDYDDMS(1)PR;RDYDDMS(1)PR;RDYDDMS(1)PR;RDYDDMS(1)PR;RDYDDMS(1)PR 116.84 0.0014514 376174500.0 474713.0 401914.0 681058.0 925080.0 731446.0 622691.0 542987.0 693066.0 548548.0 699801.0 True False 625661.8593562024 531824.8406433595 672026.7259246072 711817.0983435262 629897.3485769999 583754.0333331521 591311.7910947999 585968.5747722978 577543.1273970633 675301.1799928478 0.9264930639730687 0.7875372595217323 0.9951511204700171 1.0540735296080264 0.932765064298675 0.8644350856003756 0.8756267701191675 0.8677144245157454 0.8552378472123803 1.0 19.365171552856808 -6.687028012628006 6.9547608602639 0.8833913542421603 0.940761726482585 0.0843223508758294 0.07386916707446105 0.530787281114026 40.703460879430025 0.026022240626787308 0.025914286970799054 2.0557579923164064e-07 6.687028012628006 0.05737037224042474 RDYDDMS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 RDYDDMSPR 9 1 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 RDYDDMS(1)PR;RDYDDMS(1)PR;RDYDDMS(1)PR;RDYDDMS(1)PR;RDYDDMS(1)PR;RDYDDMS(1)PR 102.05 0.0031768 328539300.0 516020.2 431695.0 522162.0 614692.0 680174.0 591391.0 540103.0 562582.0 528386.0 396148.2 True False 603372.2279964808 474550.8266271366 534612.3223904129 580252.8000983524 546898.787369912 560377.4148756441 488940.53383290203 547814.8186048998 536112.6456418966 467966.7327525743 1.289348549302753 1.0140695767749017 1.1424152294882803 1.2399445505139068 1.1686702260929114 1.197472759611589 1.0448190001818294 1.1706276969361904 1.1456212762998963 1.0 18.836046448265186 -14.522878706460075 0.2495586715641133 0.0649905129896466 1.1671599357224274 0.28585595718324086 0.07647561244117142 249.28832585224137 2.467715860201657 118.7209940659817 0.10925380827279181 3.000000268160887e-15 14.522878706460075 1.1021694227327807 RDYDDMS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 7 RDYDDMSPR 9 1 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 RDYDDMS(1)PR;RDYDDMS(1)PR;RDYDDMS(1)PR;RDY(0.002)DDMS(0.998)PR;RDYDDMS(1)PR;RDYDDMS(1)PR;RDY(0.001)DDMS(0.999)PR 130.56 0.0018535000000000001 365705400.0 430115.0 407046.0 520338.0 435722.0 469355.0 463304.6 408531.0 429329.6 517707.0 393930.9 True False 423981.4812265702 406103.50999583135 477557.8182027661 467766.44940598134 441748.46168743377 443490.1422737725 429682.736222465 449277.8205607612 459397.38596360537 462021.3311850702 0.9176664638818104 0.8789713430637252 1.0336272071634556 1.012434746694866 0.956121356029954 0.9598910533767655 0.9300062729145909 0.9724179171736026 0.9943207271085633 1.0 18.817599935784834 -5.244955462664207 24.899608260976876 0.9788331866688323 0.8983188936860832 0.5580958351432489 0.029778955647215204 639.2798226589035 965653.7515974226 0.00822174410874537 0.021609281693352425 5.689112702752009e-06 5.244955462664207 -0.08051429298274915 RDYDDMSPR ddPTM_PC-9_AZD4547_30min_R2 2 RDYDDMSPR 9 1 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 ; 94.40899999999999 0.0053405 26384000.0 11540.5 11603.0 17209.5 25069.0 20075.6 17949.8 13301.8 19049.6 12788.2 18077.1 False True 15210.138942687983 15353.442840968224 16981.290785512447 19289.729362189075 17288.44947008037 16827.396168442177 14485.634430998918 16105.922036259693 13464.158144372257 17444.226231241002 0.8719296998939412 0.8801446758052026 0.9734619673242095 1.1057944964989588 0.9910700102661103 0.9646398725502574 0.8303970745951735 0.9232809654472074 0.7718403766318502 1.0 14.090461985272679 -7.2352622676378955 19.081812953362107 0.8749865399634437 0.9687090959727045 0.1955177671514109 0.08193262140963227 62.684533635339776 45693.16689589493 0.032707787455738865 0.02530211323593305 5.8175179551174864e-08 7.2352622676378955 0.09372255600926083 RDYDDMSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RDYDDMSPR 9 1 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 70.808 0.034024 7554100.0 8776.4 7646.4 9296.5 11225.0 11715.0 13582.0 9832.2 10905.0 10181.0 7744.5 False True 10262.071178198654 8405.48405870287 9518.16381717258 10596.099641941013 9419.529846831152 12869.73601025549 8900.822837036396 10618.755304802575 10329.877864440305 9148.516544571736 1.1217196939199552 0.9187810961210161 1.0404051597655113 1.1582314564680105 1.0296237429247719 1.4067565979198822 0.9729252599228988 1.1607078866904605 1.1291314623647404 1.0 13.159322110321314 -5.647526679168866 5.22922731466671 1.1306471842376347 1.0111411641104593 0.10987544489502687 0.12287079407557454 0.3801697517274491 15.791069709870913 0.032120514214269674 0.0565575148340894 2.251507100036263e-06 5.647526679168866 -0.11950602012717537 RDYDDMSPR ddPTM_PC-9_Lapatinib_30min_R1 1 RDYDDMSPR 9 1 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 74.533 0.025317 7209600.0 8232.2 5565.2 7390.9 4384.3 7293.9 5810.6 6637.1 6013.0 4511.8 5308.5 False True 8114.807318399414 5552.3141213248655 6783.248731699043 4706.736047596055 6864.887142359143 5562.094183170168 6980.736562420289 6292.385931535725 4003.633572639727 6226.067151868378 1.3033600699221892 0.8917851327155497 1.0894917395266868 0.7559725799268986 1.1026040957973062 0.8933559577013304 1.1212112545759234 1.0106517931865617 0.6430437505702582 1.0 12.60410542188438 -4.755297388058173 24.990092506421487 0.9530511286910992 1.303360647855586 0.34598983376722137 0.1473239928738609 231.38445202852745 941349.2561814383 0.0347487131278672 0.312229344265 1.756720267932072e-05 4.755297388058173 0.3503095191644867 RDYEVDGR ddPTM_PC-9_AZD4547_30min_R2 1 RDYEVDGR 8 1 Q12959-3;Q12959;Q12959-5;A0A590UK48;Q12959-8;A0A590UJX2;A0A590UJS9;A0A590UJ68;A0A590UJ18;Q12959-9;Q12959-6;A0A590UJ08;A0A590UJR5;A0A590UJC5;A0A590UKA8;A0A0C4DFT3;A0A590UJD9;A0A590UJR4;A0A590UJ81;C9JUA9;Q12959-7;Q12959-2;Q12959-4;A0A590UK81;A0A590UJ29;Q15700-3;A0A3B3ITF1;B7Z2T4;F8VYC1;A0A3B3ISW2;Q15700;E9PN83;E9PIW2;F8W750;Q15700-4;Q15700-5;B5MCC5;Q15700-2;H7C325 Q12959-3 DLG1;DLG2 Disks large homolog 1;Disks large homolog 2 0 93.598 0.020575 0.0 16810.0 15009.0 18165.0 24543.0 26987.0 22692.0 19324.0 25247.0 17719.0 20340.0 False True 22155.230330279017 19860.365733008028 17924.120231199842 18884.99053557008 23240.320879528324 21273.065652781075 21043.79856445167 21345.656268344148 18655.590165944548 19627.902791014156 1.128761975549517 1.0118434936462135 0.913195893725624 0.9621501969235252 1.184045036648947 1.083817557040281 1.0721368853571929 1.0875158948777959 0.9504627348412006 1.0 14.260618411006627 -4.752777194202758 24.33544408776873 1.034323891820059 1.1287622292864616 0.13047695494389688 0.07597531541502223 586.9619318550431 1648826.3980687677 0.020453895946336297 0.23185227404158654 1.7669440822955924e-05 4.752777194202758 0.09443833746640262 RDYEVDGR ddPTM_PC-9_Lapatinib_30min_R1 1 RDYEVDGR 8 1 Q12959-3;Q12959;Q12959-5;A0A590UK48;Q12959-8;A0A590UJX2;A0A590UJS9;A0A590UJ68;A0A590UJ18;Q12959-9;Q12959-6;A0A590UJ08;A0A590UJR5;A0A590UJC5;A0A590UKA8;A0A0C4DFT3;A0A590UJD9;A0A590UJR4;A0A590UJ81;C9JUA9;Q12959-7;Q12959-2;Q12959-4;A0A590UK81;A0A590UJ29;Q15700-3;A0A3B3ITF1;B7Z2T4;F8VYC1;A0A3B3ISW2;Q15700;E9PN83;E9PIW2;F8W750;Q15700-4;Q15700-5;B5MCC5;Q15700-2;H7C325 Q12959-3 DLG1;DLG2 Disks large homolog 1;Disks large homolog 2 0 86.13600000000001 0.032406 0.0 16737.0 15774.0 21368.0 22939.0 18564.0 19372.0 16855.0 11382.0 22159.0 14082.0 False True 16498.327310810106 15737.476272151673 19611.20552286531 24626.010582260773 17472.102018228252 18543.50471833762 17727.6694278516 11910.849272033864 19663.22007538538 16516.054936914476 0.9989266428228725 0.9528592834223003 1.187402536366779 1.4910346736144604 1.0578859228166497 1.122756299199009 1.0733598002407394 0.721167937351209 1.1905518691050598 1.0 14.01158150198232 -7.533633722919218 24.958759186806503 0.952968703146461 1.1382456318110454 0.15078842368767775 0.17313038123158664 385.042127660798 893543.2947487824 0.08409815739409701 0.04861175699143215 2.9266196018621985e-08 7.533633722919218 0.18527692866458445 RDYS(ph)YER ddPTM_PC-9_Lapatinib_30min_R1 1 RDYSYER 7 1 P48634;P48634-2;P48634-3 P48634 PRRC2A Protein PRRC2A 1 RDYS(0.996)Y(0.004)ER 56.548 0.041611 5853500.0 17737.0 15717.0 19959.0 14749.0 19252.0 18517.0 16070.0 14397.0 17239.0 14032.0 True False 17484.067127432565 15680.608252149608 18318.048063968006 15833.690661221684 18119.635210888307 17725.07107523527 16902.025968886108 15065.937178832492 15297.362285282205 16457.41250353527 1.0623825053711666 0.9527991261555366 1.11305760003482 0.9621008562445887 1.1010014610131436 1.0770266025371662 1.0270160005563043 0.9154499333109702 0.9295119923618691 1.0 14.006449907182725 -7.677224686198463 5.822146560054505 0.9423108542814601 1.0429936740021832 0.3918630890284437 0.053661062372887945 0.19262602892088942 10.285023438394983 0.025005872552397102 0.014081506993373731 2.1026903123654e-08 7.677224686198463 0.10068281972072313 REAALPPVS(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 1 REAALPPVSPLK 12 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 REAALPPVS(1)PLK 81.594 0.0059745 5601400.0 34856.0 37772.0 41053.0 43040.0 44558.0 39182.0 40430.0 39809.0 32706.0 31208.0 True False 45939.48295016095 49981.06032828164 40508.61039644632 33117.79296137132 38371.890827065785 36731.94334599278 44028.19167671194 33657.433769814714 34434.77238937766 30115.41741897593 1.5254473252366134 1.6596502592983564 1.345112034572749 1.0996956309994088 1.2741610150449847 1.2197056024482575 1.4619817837547049 1.117614718785433 1.1434267010252388 1.0 14.878214635286328 -1.5228787452803376 0.2766545542378676 1.1143580102515491 4.897135895722447 0.5616574288109748 0.13259966044522947 41.825139081894264 0.5878736874182177 0.15875816028759074 76.16650976297902 0.029999999999999995 1.5228787452803376 3.7827778854708978 REAALPPVS(ph)PLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 REAALPPVSPLK 12 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 REAALPPVS(1)PLK 58.711999999999996 0.030774 4827800.0 40516.0 45973.0 40285.0 60865.0 54923.0 55217.0 65762.0 53338.0 53039.0 48824.0 True False 47374.55857252366 50536.89561502761 41245.54718171329 57454.93137699243 44161.23241805441 52321.323316026916 59532.54728435023 51937.93401628243 53814.5950350702 57675.40470942864 0.82139967307033 0.8762295794825339 0.7151323408914123 0.9961773422562534 0.7656856963646937 0.9071687243396759 1.032199905389099 0.9005213622331416 0.9330596864675786 1.0 15.815668601912188 -6.995431451260495 24.287716252009908 0.9598023521056741 0.839213355401592 0.3970934168036603 0.0762982952899131 96.25363910612391 511705.5803246493 0.025663984418336148 0.022539056874092946 1.0105749963963414e-07 6.995431451260495 -0.12058899670408207 REAALPPVS(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 2 REAALPPVSPLK 12 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 REAALPPVS(1)PLK;REAALPPVS(1)PLK 77.13 0.008206200000000002 9372100.0 57571.0 63574.0 60523.0 46876.0 61451.0 81029.0 75580.0 68181.0 75613.0 57550.0 True False 56750.02698277159 63426.79830897493 55547.03256553615 50323.417413751966 57836.57299731443 77563.57855782457 79493.16258421972 71348.93816697769 67096.66769981106 67497.44081944531 0.8407730173737564 0.9396918985216152 0.8229502021287542 0.7455603768499369 0.8568706056875021 1.149133620714688 1.1777211345962404 1.0570613833765206 0.9940623953327903 1.0 16.04254518264495 -6.740019888730591 13.816794692894403 1.085540429632734 0.8402861853430585 0.7385182747361045 0.06961898974284686 0.8277727155423388 532.9713569020109 0.02474975108950946 0.02455727714428828 1.819617526417316e-07 6.740019888730591 -0.24525424428967546 REASSS(ph)SPEAGEGQIR ddPTM_PC-9_Lapatinib_30min_R1 1 REASSSSPEAGEGQIR 16 1 J3QSS7;Q86U28-2;Q86U28 J3QSS7 ISCA2 Iron-sulfur cluster assembly 2 homolog, mitochondrial 1 REAS(0.033)S(0.012)S(0.906)S(0.049)PEAGEGQIR 57.413999999999994 0.026425 5660300.0 9503.8 9362.8 12577.0 8957.8 11076.0 14772.0 10389.0 11664.0 14300.0 11339.0 True False 9368.274069216526 9341.121011848712 11542.96760862397 9616.586494344803 10424.531456253831 14140.23599521388 10926.891586232592 12205.952021525467 12689.38341432424 13298.93104173222 0.704438126629784 0.7023963792680895 0.8679620619433237 0.7231097344717278 0.7838623588273009 1.063261096011524 0.8216368332119224 0.9178145208229918 0.9541656674889726 1.0 13.699022667172917 -6.613190337859429 8.106169179750601 0.9377551337071355 0.7544725302077929 0.6422929857309831 0.07272534311449994 0.17227292643516337 13.592781293544038 0.023751137562868906 0.023735110741754068 2.436742635265068e-07 6.613190337859429 -0.18328260349934256 REASSSS(ph)PEAGEGQIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 REASSSSPEAGEGQIR 16 1 J3QSS7;Q86U28-2;Q86U28 J3QSS7 ISCA2 Iron-sulfur cluster assembly 2 homolog, mitochondrial 1 REAS(0.002)S(0.003)S(0.266)S(0.729)PEAGEGQIR 55.536 0.029885000000000002 3958000.0 7150.1 8413.5 9748.7 12210.0 15408.0 11195.0 13548.0 12131.0 7810.9 9760.8 True False 8360.470709087806 9248.736677115588 9981.145980150628 11525.913285354098 12388.913007253468 10607.914492328835 12264.635360974058 11812.574103856956 7925.119635728983 11530.355773549718 0.7250834990075907 0.8021206681524873 0.8656407639256952 0.999614713692893 1.0744606021327854 0.9199988882097693 1.0636823010360839 1.024476116422586 0.6873265484061614 1.0 13.493149408134725 -5.389465852397127 2.078767647151102 0.9739948632201249 0.7464715038552459 0.3775499030058892 0.10496214393116264 0.35434325157019647 2.887792838281253 0.02994460378214251 0.09204169735396567 4.078816313300369e-06 5.389465852397127 -0.227523359364879 REDEGEPGDEGQLEDEGS(ph)QEK ddPTM_PC-9_Lapatinib_30min_R1 1 REDEGEPGDEGQLEDEGSQEK 21 1 Q969E4 Q969E4 TCEAL3 Transcription elongation factor A protein-like 3 1 REDEGEPGDEGQLEDEGS(1)QEK 91.809 0.00056709 0.0 16394.0 17414.0 20987.0 16179.0 21395.0 18894.0 17179.0 19203.0 20899.0 18182.0 True False 16160.218553708606 17373.678952912975 19261.529872162766 17368.857631561837 20136.588164188393 18085.94766406519 18068.44456250744 20095.241483998085 18545.134543773594 21324.734474007873 0.7578156986388669 0.8147195911906556 0.9032482864272054 0.8144935006216493 0.9442831838648365 0.8481206500418398 0.8472998613197537 0.9423442767126416 0.8696537143933841 1.0 14.380240157415782 -1.52287875292137 0.057104966535668406 1.1820558473229956 0.2530146623446099 0.5575851084915749 0.04622490822497167 295.5201646961481 1.2696117085407592 4.3776216239389685 23.178895445359363 0.029999999472176176 1.52287875292137 -0.9290411849783857 REDIFYTS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 REDIFYTSK 9 1 A0A0A0MSS8;P42330;S4R3Z2;S4R3D5;A6NHU4;P17516;B4DK69;P52895;H0Y804;S4R3P0;P52895-2;Q04828 A0A0A0MSS8;B4DK69;Q04828 AKR1C3;AKR1C1;AKR1C4;AKR1C2 Aldo-keto reductase family 1 member C3;Aldo-keto reductase family 1 member C4;Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 1 REDIFYT(0.199)S(0.801)K 84.605 0.0059955 4526100.0 14877.0 26399.0 18604.0 17182.0 19593.0 20744.0 17001.0 21784.0 17664.0 14786.0 True False 19607.57653917674 34931.96048941827 18357.29880436235 13220.955359253756 16872.850149798007 19446.874400726705 18514.05606469896 18417.783346520733 18597.68297822927 14268.346640508136 1.3742010222481154 2.448213613639418 1.2865750508363454 0.9265933672875024 1.1825371624975545 1.3629381799231468 1.2975614155698438 1.290814122375767 1.3034224249521704 1.0 13.800530550261264 -5.4146842455385125 8.601556914120126 1.2093709492754368 1.9084562511446466 0.516887788224502 0.2735594668711615 0.22276522157480808 16.125823524809277 0.06708619927958721 0.13999102107089464 3.848715017565551e-06 5.4146842455385125 0.6990853018692098 REDIFYTS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 REDIFYTSK 9 1 A0A0A0MSS8;P42330;S4R3Z2;S4R3D5;A6NHU4;P17516;B4DK69;P52895;H0Y804;S4R3P0;P52895-2;Q04828 A0A0A0MSS8;B4DK69;Q04828 AKR1C3;AKR1C1;AKR1C4;AKR1C2 Aldo-keto reductase family 1 member C3;Aldo-keto reductase family 1 member C4;Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 1 REDIFYT(0.063)S(0.937)K;REDIFYT(0.207)S(0.793)K 75.819 0.011651 6564100.0 21717.1 31346.0 25816.1 31601.0 32571.0 26241.0 29312.0 19420.9 22742.0 21409.3 True False 25393.376097723223 34457.82372150297 26431.653732104467 29830.498421824326 26188.946362879873 24864.875765359615 26535.355159497452 18911.121953144473 23074.55872636297 25290.636614074458 1.0040623526096448 1.3624735607614913 1.0451161880755118 1.1795076129172406 1.0355194597318083 0.9831652775210133 1.0492165762537704 0.7477519147390805 0.9123755593214993 1.0 14.626315732422828 -6.784669377370233 0.9904595887930336 0.8912442694103265 1.1667313159337314 0.42659927277517684 0.11502663898413244 0.4540646876869519 0.9547247635844133 0.06432084025777557 0.05728079397100459 1.6418392079662526e-07 6.784669377370233 0.27548704652340483 REDIFYTS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 2 REDIFYTSK 9 1 A0A0A0MSS8;P42330;S4R3Z2;S4R3D5;A6NHU4;P17516;B4DK69;P52895;H0Y804;S4R3P0;P52895-2;Q04828 A0A0A0MSS8;B4DK69;Q04828 AKR1C3;AKR1C1;AKR1C4;AKR1C2 Aldo-keto reductase family 1 member C3;Aldo-keto reductase family 1 member C4;Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 1 REDIFYT(0.253)S(0.747)K;REDIFYT(0.082)S(0.918)K 117.27 0.00085649 8879600.0 40007.0 51489.0 40012.0 36732.0 47020.0 43726.0 54501.0 50746.0 39490.0 46243.0 True False 39436.49284361474 51369.78038397475 36722.36781078651 39433.393814359944 44254.376044876786 41855.94091028449 57322.79510455894 53103.844417380984 35042.220351864635 54236.04093507569 0.7271270572795488 0.9471521058380339 0.6770842262388904 0.7270699176137222 0.815958821512292 0.7717366568180918 1.0569133387368432 0.979124646670836 0.6461057951079543 1.0 15.726964249546624 -7.20236659753782 24.996489254719393 0.9187967036061772 0.7802567869560322 0.24696727378833905 0.1221341301316333 386.5252635060307 163557.03882573874 0.04640801249657424 0.035947483971553645 6.275284246152422e-08 7.20236659753782 -0.13853991665014498 REDIFYTSK ddPTM_PC-9_AZD4547_30min_R2 3 REDIFYTSK 9 1 A0A0A0MSS8;P42330;S4R3Z2;S4R3D5;A6NHU4;P17516;B4DK69;P52895;H0Y804;S4R3P0;P52895-2;Q04828 A0A0A0MSS8;B4DK69;Q04828 AKR1C3;AKR1C1;AKR1C4;AKR1C2 Aldo-keto reductase family 1 member C3;Aldo-keto reductase family 1 member C4;Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 ;; 140.78 0.00047794 188353300.0 761589.0 758902.0 966204.0 1274501.0 1157201.0 1040025.0 942178.0 1116276.0 865641.0 973215.0 False True 1003758.4599647146 1004202.2303625325 953391.5036535203 980684.4852941621 996543.6158932479 974992.0723397512 1026030.016759362 943781.1936706189 911397.0160188733 939143.0390735922 1.0688025340153313 1.0692750609674084 1.0151717725491352 1.044233353698227 1.0611201642683503 1.038172069402252 1.0925172993578045 1.0049387094447317 0.9704560201158615 1.0 19.84098538316362 -7.942276982881194 7.152170835965771 0.9859509297142691 1.05357693180305 0.6714482066066698 0.020721912071788525 0.12036744163746756 12.13313719692357 0.011511821668626947 0.005458435292596178 1.1421496660589873e-08 7.942276982881194 0.06762600208878078 REDIFYTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 REDIFYTSK 9 1 A0A0A0MSS8;P42330;S4R3Z2;S4R3D5;A6NHU4;P17516;B4DK69;P52895;H0Y804;S4R3P0;P52895-2;Q04828 A0A0A0MSS8;B4DK69;Q04828 AKR1C3;AKR1C1;AKR1C4;AKR1C2 Aldo-keto reductase family 1 member C3;Aldo-keto reductase family 1 member C4;Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 ;;; 161.67 7.9615e-05 186914000.0 1303050.0 1336010.0 1271520.0 1577020.0 1673590.0 1329990.0 1558620.0 1283310.0 1191600.0 1193700.0 False True 1523630.6285893694 1468640.243417508 1301837.8590664535 1488664.6821678253 1345662.0534663382 1260242.9830864144 1410976.2301683957 1249624.4722793375 1209024.8957142788 1410108.3606760015 1.080506059732137 1.0415087835614607 0.9232183109972886 1.0557094218306486 0.9542969114949663 0.8937206658942565 1.000615462979014 0.8861903858794734 0.8573985726420883 1.0 20.42737460102842 -3.597637668265013 0.41092779154173725 0.9202085652255679 1.4530993690828735 0.4120732530596536 0.0565852045741369 13.835579159344002 0.8595794960653643 0.04169491880702612 4.420747498152222 0.0002525586990096268 3.597637668265013 0.5328908038573056 REDIFYTSK ddPTM_PC-9_Lapatinib_30min_R1 4 REDIFYTSK 9 1 A0A0A0MSS8;P42330;S4R3Z2;S4R3D5;A6NHU4;P17516;B4DK69;P52895;H0Y804;S4R3P0;P52895-2;Q04828 A0A0A0MSS8;B4DK69;Q04828 AKR1C3;AKR1C1;AKR1C4;AKR1C2 Aldo-keto reductase family 1 member C3;Aldo-keto reductase family 1 member C4;Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 ;;; 211.64 8.937200000000001e-05 267314000.0 1543740.0 1503000.0 1558690.0 1341260.0 1475010.0 1533450.0 1320220.0 1262920.0 1459460.0 1266110.0 False True 1521725.9845127584 1499519.8958440423 1430540.5249173986 1439900.734712197 1388252.8117812374 1467867.9181465402 1388574.5317139265 1321599.8737161313 1295080.2460048704 1484955.4265144677 1.0247620617708368 1.00980801784991 0.9633558687180306 0.9696592294975315 0.9348784394423113 0.9884929149637603 0.9350950923646446 0.8899929587908444 0.8721340875831687 1.0 20.501988196032606 -5.132913227289697 0.5038816911682461 0.9224078562268657 1.0734703188774863 0.41944008384593956 0.03658140606562819 3.131164631020832 0.7892696841809343 0.02511210417991588 0.2686667736459651 7.363542075092796e-06 5.132913227289697 0.15106246265062062 REDLFIVS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 REDLFIVSK 9 1 O60218 O60218 AKR1B10 Aldo-keto reductase family 1 member B10 1 REDLFIVS(1)K 66.393 0.022264 2368000.0 15181.0 14930.0 17798.0 13848.0 12982.0 14860.0 12979.0 13475.0 17136.0 10780.0 True False 14964.516156145555 14895.43050229646 16334.717142266793 14866.42811557378 12218.42428359401 14224.4724403519 13650.989113265257 14101.09769290602 15205.9632299203 12643.308636552898 1.1835917785698788 1.1781275717048054 1.2919653875285235 1.1758336795317685 0.9663945281118496 1.1250593376505673 1.0797006943102747 1.1153012315256252 1.2026886052562655 1.0 13.62608643237786 -6.013217359445807 24.809028338997102 1.0877146606071453 1.2172484140477353 0.45900378698677813 0.06789487991017286 526.8098690770171 988826.3037431416 0.019594488247268286 0.026540895085810465 9.700243595822326e-07 6.013217359445807 0.12953375344059004 REDLFIVSK ddPTM_PC-9_AZD4547_30min_R2 2 REDLFIVSK 9 1 O60218 O60218 AKR1B10 Aldo-keto reductase family 1 member B10 0 ; 144.55 0.00034331 29849000.0 127863.0 123569.0 179522.0 201710.0 177786.0 159034.0 144692.0 176446.0 143586.0 145808.0 False True 168520.77428438264 163510.26272650211 177141.4209824089 155208.87588843433 153103.48270974244 149089.5788394317 157569.30769445468 149180.3250257157 151175.66282337141 140703.3063005014 1.197703015766177 1.1620925408624847 1.2589712753734887 1.103093310095736 1.0881299575346002 1.059602526475246 1.1198692613372738 1.0602474735533922 1.0744286456247454 1.0 17.102296704413483 -5.114350211499461 0.230360845245945 1.0011727832365807 1.3635565627540118 0.6868695539694395 0.04017444673223827 5.9662855249975815 0.3205961532214569 0.07368099482461148 0.6183143896682923 7.685104698264486e-06 5.114350211499461 0.36238377951743117 REDLFIVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 REDLFIVSK 9 1 O60218 O60218 AKR1B10 Aldo-keto reductase family 1 member B10 0 ; 150.04 0.00014996 32866000.0 300350.0 315480.0 312998.0 375710.0 368870.0 344300.0 348070.0 294107.0 309855.0 277087.0 False True 351193.3228170964 346798.76946531504 320461.05937152496 354660.18676825403 296592.57145545044 326244.3018944905 315098.2897914265 286387.0028821243 314386.0431869314 327320.6796805153 1.0729335010543246 1.0595076663161385 0.9790431196840793 1.0835251445598357 0.9061223132768227 0.9967115497038701 0.9626592798810677 0.8749431999275304 0.9604832896405785 1.0 18.320345227232124 -6.027186983609952 0.8637409597252032 0.9414771601532085 1.0665155317888892 0.4303475122810133 0.04926866014277272 0.6209665722588862 0.940114888318303 0.022820009958445724 0.05117980740150814 9.393188038450991e-07 6.027186983609952 0.12503837163568077 REDLFIVSK ddPTM_PC-9_Lapatinib_30min_R1 2 REDLFIVSK 9 1 O60218 O60218 AKR1B10 Aldo-keto reductase family 1 member B10 0 ; 173.64 0.00085402 114824000.0 268330.0 252910.0 278030.0 253660.0 253360.0 252580.0 263090.0 233753.0 230455.0 243060.0 False True 264503.56499430427 252324.4024337438 255171.44662683626 272315.0025849549 238457.86292492537 241777.7421927375 276711.51289074373 244614.0177372804 204498.73110126524 285072.5971429081 0.9278463368462859 0.8851233158241881 0.8951104005935644 0.9552479098804515 0.8364811816878542 0.8481269143927338 0.9706703333257496 0.8580762240526906 0.7173566773896165 1.0 18.12096984003295 -6.270506388657059 24.91993121508579 0.8684503748682805 0.9121584013607785 0.07586326835569379 0.0743307297993475 1885.102198405698 5181033.487906763 0.022928187460570567 0.02635518448584608 5.364059806215018e-07 6.270506388657059 0.04370802649249805 REDLVVAPAGITLK ddPTM_PC-9_Lapatinib_30min_R1 1 REDLVVAPAGITLK 14 1 P12268;H0Y4R1;E7ETK5 P12268 IMPDH2 Inosine-5-monophosphate dehydrogenase 2 0 124.78 0.00080595 0.0 25935.0 26674.0 29826.0 25439.0 26271.0 25611.0 25530.0 20760.0 26039.0 21118.0 False True 25565.162144103506 26612.23799184566 27373.821411689467 27309.868922016303 24725.79143077325 24515.677232156948 26851.81848075061 21724.58538810604 23106.21361717405 24768.21816203379 1.0321760724512399 1.0744510492336705 1.1051994629815438 1.102617424610645 0.9982870495171278 0.9898038313364038 1.084123948888285 0.8771153922330508 0.9328976943764424 1.0 14.596202463666136 -7.12143943731001 0.9248068820219622 0.9420340523144897 1.0757783728814312 0.44352703756800693 0.05332239042771589 0.5183958007443628 0.8925411257363907 0.039273546043129944 0.02552839377645645 7.56067487163816e-08 7.12143943731001 0.13374432056694152 REDPGTGMGS(ph)S(ph)LAT(ph)AELPGTQDPGMSGLSQTELEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 REDPGTGMGSSLATAELPGTQDPGMSGLSQTELEK 35 1 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 3 REDPGT(0.292)GMGS(0.802)S(0.801)LAT(0.804)AELPGT(0.158)QDPGMS(0.059)GLS(0.059)QT(0.025)ELEK 40.986000000000004 0.021127 1624300.0 924.47 0.0 1267.5 886.68 2455.9 2203.9 2692.4 737.28 971.41 891.4 True False 1080.9645118852047 0.0 1297.7220070205185 837.0021942553457 1974.6840248256635 2088.323604255787 2437.3563807120277 717.927181212732 985.6150335228333 1053.003763681483 1.0265533221894347 0.0 1.2324001601698538 0.794871037620076 1.8752867681325538 1.983206210920507 2.31467015102644 0.6817897579992825 0.9360033340022955 1.0 10.04029487756409 -6.178614461968504 6.909437889504343 1.516621854859835 0.7356602528719698 0.2691812634879911 0.5620793513885396 0.3559992463292204 25.404111062498643 0.17749321047698607 0.22983266751275788 6.628046369039758e-07 6.178614461968504 -0.7809616019878651 REDPSFER ddPTM_PC-9_AZD4547_30min_R2 1 REDPSFER 8 1 Q9NWH9;Q9NWH9-3;H7C3F4;H0YMM0 Q9NWH9 SLTM SAFB-like transcription modulator 0 96.03399999999999 0.003951 3419900.0 3362.4 4341.0 5063.0 5656.7 5791.7 4133.6 3594.1 5232.0 4359.9 4376.8 False True 4431.573257735287 5744.143357118251 4995.861311894565 4352.6352101438 4987.622427019095 3875.125338548203 3913.967937305722 4423.514619399398 4590.355413087742 4223.569564194239 1.0492483171827975 1.3600210129874117 1.1828528537205854 1.0305584278861484 1.1809021613618478 0.9175000623643069 0.9266966905166667 1.047340301175625 1.0868426205177177 1.0 12.044247097756983 -6.0542494342717434 1.3212879159833097 1.0056556882439716 1.2143635442555931 0.36876942498226006 0.10048179964339117 0.4470812405852258 1.5832618008545543 0.037355367773401496 0.06507095432744951 8.82572854721029e-07 6.0542494342717434 0.20870785601162156 REDPSFER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 REDPSFER 8 1 Q9NWH9;Q9NWH9-3;H7C3F4;H0YMM0 Q9NWH9 SLTM SAFB-like transcription modulator 0 66.962 0.030133999999999998 2531500.0 4430.9 4856.5 5204.4 7596.9 5310.1 4723.3 5290.5 3678.3 6803.6 4881.7 False True 5180.963855735886 5338.62122450964 5328.492633796912 7171.270322482111 4269.624023871801 4475.601833105562 4789.345540096934 3581.7485224810034 6903.089778853366 5766.7135664840625 0.8984257317456283 0.9257649375092115 0.924008548780006 1.2435627744997224 0.7403912080334121 0.7761096127814642 0.8305155934798709 0.6211074091312598 1.1970578561373122 1.0 12.49353364996061 REDPSFER ddPTM_PC-9_Lapatinib_30min_R1 2 REDPSFER 8 1 Q9NWH9;Q9NWH9-3;H7C3F4;H0YMM0 Q9NWH9 SLTM SAFB-like transcription modulator 0 ; 70.816 0.02348 4622600.0 4601.5 8470.1 5203.35 4939.04 7732.400000000001 6752.6 6206.3 6677.9 7789.6 6030.0 False True 4535.88176618825 8450.488003851397 4775.550648511847 5302.2734777544465 7277.595434483309 6463.807039079424 6527.631846340879 6988.1796128725055 6912.2532198755325 7072.277465530058 0.641360832955992 1.1948750660644567 0.6752493340069945 0.7497264500152141 1.0290313792061978 0.9139640053128161 0.9229886522631845 0.9881088018580377 0.9773730249648043 1.0 12.78795916152544 -6.266611498339356 24.85466629023437 0.9659729511320695 0.8324113897106082 0.2151174520620135 0.14481840307868338 743.5158944335334 3572969.0633095456 0.04355898669891229 0.050908846302430644 5.41238275552401e-07 6.266611498339356 -0.13356156142146125 REDS(ph)FESLDSLGSR ddPTM_PC-9_AZD4547_30min_R2 2 REDSFESLDSLGSR 14 1 E9PMS6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 REDS(1)FESLDSLGSR;REDS(0.68)FES(0.046)LDS(0.247)LGS(0.027)R 137.81 3.5366e-05 5841600.0 9608.2 10629.0 16752.4 23582.9 19037.2 14779.6 13924.6 19286.2 16191.2 20059.1 True False 12663.407737024794 14064.616388576333 16530.25223017628 18146.226757172943 16394.213385991654 13855.429275596833 15163.86242447545 16305.96094278681 17047.03377701008 19356.837014514855 0.6542085221634636 0.7265968287086307 0.8539748626173252 0.9374582605394607 0.8469469146068824 0.7157899436363103 0.7833853440572303 0.8423876757633324 0.8806724861209116 1.0 14.240555609213708 -14.522878745280336 0.0495949499106228 1.7274261913526214 0.43861489940199505 0.45973064218924875 0.07368617775598443 655.825008633051 2.397332575376573 64.31381274729407 14.493963083285937 3.0000000000000132e-15 14.522878745280336 -1.2888112919506263 REDS(ph)FESLDSLGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 REDSFESLDSLGSR 14 1 E9PMS6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 REDS(0.754)FES(0.231)LDS(0.015)LGSR;REDS(0.974)FES(0.016)LDS(0.009)LGSR 147.53 0.00030205 8722200.0 13945.4 12484.900000000001 18142.4 17919.9 18655.5 15323.0 19617.0 17501.2 15465.9 14632.1 True False 16306.08078579503 13724.318362170361 18574.983621435153 16915.906100099666 15000.08869462728 14519.43490540015 17758.735745219077 17041.812044054182 15692.059528891798 17284.78390236013 0.9433777638127449 0.7940115676133152 1.0746436707779061 0.9786588131882809 0.8678204355554084 0.8400125212683516 1.0274201775119811 0.9859430201917206 0.9078539608903727 1.0 14.077214946416047 -14.52286528337378 0.05237161119616241 1.2530368956379194 0.8153064903290744 0.05933103793642369 0.08143666710756178 1691.1745954738137 6.507496886917575 58.36489162882933 12.117690077428518 3.000092992997336e-15 14.52286528337378 -0.437730405308845 REDS(ph)FESLDSLGSR ddPTM_PC-9_Lapatinib_30min_R1 3 REDSFESLDSLGSR 14 1 E9PMS6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 REDS(1)FESLDSLGSR;REDS(1)FESLDSLGSR;REDS(0.907)FES(0.033)LDS(0.06)LGS(0.001)R 152.25 7.7777e-05 15228500.0 37508.1 37408.2 47649.5 42337.8 43209.7 38667.9 34195.0 40236.7 46333.2 35961.7 True False 36973.22761585688 37321.58361125294 43731.942042389106 45451.46304676052 40668.190399538755 37014.16405627745 35965.44978258 42106.243973295066 41114.667105773995 42177.63192904678 0.8766074794823712 0.8848667387025684 1.0368515263245945 1.0776200788897095 0.964212274125601 0.8775780517631819 0.8527138233621743 0.9983074451436296 0.9747979017631678 1.0 15.364190476574695 -13.21608344896363 0.005113357680904049 1.98174492006897 3.157325725637794e-08 0.043562158636076376 0.07161915699802711 238508.62233853806 115.1050349854835 23729.117333880513 20957.82606032075 6.080181603736731e-14 13.21608344896363 -1.9817448884957127 REDS(ph)PGPEVQPMDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 REDSPGPEVQPMDK 14 1 O75382-3;O75382-2;O75382;E9PMW5;E9PMK8 O75382-3 TRIM3 Tripartite motif-containing protein 3 1 REDS(1)PGPEVQPMDK 49.036 0.041181 6102800.0 21946.0 24744.0 26339.0 27437.0 29737.0 25435.0 25440.0 22439.0 27884.0 20411.0 True False 25661.024346742128 27200.420792600962 26967.021651213767 25899.79384195419 23910.24831884065 24101.14382424152 23030.13903034988 21850.00002608574 28291.750748654693 24111.352726612895 1.0642714507850397 1.1281167465390074 1.1184366948208977 1.0741742338399498 0.9916593477747818 0.9995765935454917 0.955157485002091 0.9062121181599576 1.1733788257109143 1.0 14.557424972722583 -6.138854865779388 3.3436288851024076 0.9966834083004906 1.1053214128362618 0.31890307200087686 0.06608475784175685 0.2795846378783463 5.824028368766159 0.01993508656263502 0.026719661408042605 7.263486509005074e-07 6.138854865779388 0.10863800453577122 REDS(ph)PGPEVQPMDK ddPTM_PC-9_Lapatinib_30min_R1 2 REDSPGPEVQPMDK 14 1 O75382-3;O75382-2;O75382;E9PMW5;E9PMK8 O75382-3 TRIM3 Tripartite motif-containing protein 3 1 REDS(1)PGPEVQPMDK;REDS(1)PGPEVQPMDK 81.51 0.0038476 9914300.0 44787.0 49106.0 59610.0 44865.0 50195.0 49922.0 48550.0 42948.0 56939.0 40693.0 True False 44148.3291670701 48992.29807406367 54709.09590125427 48164.521765252626 47242.62878716696 47786.95243386592 51063.68144302555 44943.52086938235 50525.93022574877 47726.73082998581 0.9250231138675128 1.0265169480932208 1.1462988340043934 1.009172866602289 0.9898567944126879 1.0012618003125886 1.0699178543136918 0.9416844625181237 1.0586505580223877 1.0 15.5425098980704 REDS(ph)YHVR ddPTM_PC-9_AZD4547_30min_R2 2 REDSYHVR 8 1 B1AVT0;P49760-2;P49760-3;P49760 B1AVT0 CLK2 Dual specificity protein kinase CLK2 1 REDS(1)YHVR;REDS(1)YHVR 104.07 0.0017714000000000002 12006100.0 24109.0 16774.0 30615.0 33436.0 37460.0 33881.0 23485.0 36186.0 23876.9 29251.0 True False 31775.16050164766 22195.867466551837 30209.02509651437 25727.84678105045 32259.325606667353 31762.41571399066 25575.11950352658 30594.28517155708 25138.98418834253 28226.93139331146 1.1257036784798 0.7863365364543763 1.0702199497205205 0.9114645308964339 1.1428562728682365 1.1252521668549829 0.9060538372792006 1.083868619838945 0.890602801914889 1.0 14.78478467857153 -4.483088600022684 23.731511844494158 0.9971093925080882 2.2568190261754104 0.11617723259314472 0.1104257232785964 431.508086100271 607407.701485441 0.02574832530094491 89618.22035518351 3.287845489964282e-05 4.483088600022684 1.2597096336673221 REDS(ph)YHVR ddPTM_PC-9_Lapatinib_30min_R1 3 REDSYHVR 8 1 B1AVT0;P49760-2;P49760-3;P49760 B1AVT0 CLK2 Dual specificity protein kinase CLK2 1 REDS(1)YHVR;REDS(1)YHVR;REDS(1)YHVR 72.531 0.014865 15635600.0 33470.6 27036.800000000003 33617.6 27156.699999999997 29061.3 27375.5 28943.8 25111.4 36096.3 25573.0 True False 32993.3031062437 26974.19795073606 30853.690695688718 29153.894310095493 27351.97147071412 26204.713680407363 30442.368340898916 26278.167317672724 32030.754583109927 29993.258976119432 1.1000239464645338 0.8993420145577664 1.0286875034238314 0.9720148895226011 0.9119372953933316 0.8736867741271964 1.0149736767564026 0.8761357789960519 1.0679317845590819 1.0 14.87235066911989 -4.746685710118219 24.894807593861138 0.9566114119062489 1.1000243431002845 0.29393056356843117 0.0646077168081635 926.3679922127924 1563027.333679882 0.015197905513511016 0.33530065932897 1.7919021472349295e-05 4.746685710118219 0.14341293119403564 REDSFES(ph)LDSLGSR ddPTM_PC-9_AZD4547_30min_R2 1 REDSFESLDSLGSR 14 1 E9PMS6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 REDS(0.001)FES(0.967)LDS(0.032)LGSR 177.39 0.00013011 6674600.0 5209.9 7263.6 8885.0 12890.0 13091.0 11071.0 9039.8 12305.0 10889.0 11787.0 True False 6866.539827348049 9611.416652560274 8767.179094644127 9918.409648514782 11273.54061710844 10378.72861986335 9844.324687586946 10403.544990770179 11464.570309665904 11374.340717683574 0.6036868419699005 0.8450086814805452 0.7707856931886946 0.8719986410372541 0.991137939061521 0.9124685885070811 0.8654852999332149 0.9146503739417522 1.0079327315949003 1.0 13.473495305441608 -3.8875409057863157 0.534580218253865 0.9490053893106906 2.1649951047569866e-13 0.7521586097615822 0.05786925601164361 5.351439342424549 0.5676643058979246 0.03180489129601568 3.9017857624255234 0.00012955646637601871 3.8875409057863157 -0.9490053893104741 REDSFES(ph)LDSLGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 REDSFESLDSLGSR 14 1 E9PMS6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 REDS(0.102)FES(0.877)LDS(0.021)LGSR 73.758 0.029004000000000002 5955100.0 9796.1 7979.4 11714.0 11511.0 13825.0 12955.0 12227.0 12678.0 10640.0 9331.6 True False 11454.38624820562 8771.54209798254 11993.306185592392 10866.075989165523 11116.090493592888 12275.616994025913 11068.770044185845 12345.215933451364 10795.589871097625 11023.345211095047 1.039102561777411 0.7957241590469236 1.087991526702899 0.9857330765826664 1.0084135333441697 1.1136017931898248 1.0041207847727636 1.1199155698241081 0.9793388181503936 1.0 13.428274478876101 -5.285645713436158 24.99789711280145 1.0403260751835726 0.9174132998844619 0.2973962308127909 0.07365298357186251 736.3053409742142 760381.7905358054 0.0177665675109304 0.03701056318692595 5.180292549210977e-06 5.285645713436158 -0.12291277529911071 REEAAVDAQQQK ddPTM_PC-9_AZD4547_30min_R2 1 REEAAVDAQQQK 12 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 122.34 0.00025635 2328300.0 11513.0 11016.0 14523.0 19813.0 14488.0 13563.0 12829.0 15466.0 15263.0 14835.0 False True 15173.894514723523 14576.706570378856 14330.415530840375 15245.418957798547 12476.591281083729 12714.903465920572 13970.75614693389 13076.085073323982 16069.771019967937 14315.631165422576 1.0599528822294586 1.0182370865761665 1.0010327428282386 1.0649491301942555 0.8715362345475348 0.8881832256639624 0.9759091992170291 0.9134131022394216 1.122533183083275 1.0 13.805303658629395 -6.2344795552194405 24.919396289929576 0.9546114988460593 1.0322703835153841 0.21507910313016443 0.06835925392836403 1111.1471540016078 1027051.0185235926 0.020268890458960097 0.026158786450954034 5.828012100111578e-07 6.2344795552194405 0.0776588846693248 REEAAVDAQQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 REEAAVDAQQQK 12 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 120.57 0.00030788 994440.0 10928.0 9554.6 13731.0 12627.0 16359.0 11786.0 12593.0 13076.0 10880.0 11784.0 False True 12777.894562161575 10503.117543848413 14058.399115107484 11919.550127286337 13153.57138406409 11167.921411932795 11400.099874575311 12732.768855167227 11039.099417062236 13920.345917907318 0.917929384622829 0.7545155562791772 1.0099173682905807 0.8562682420091924 0.9449169914048731 0.8022732680490527 0.8189523408258175 0.9146876758850959 0.7930190443659444 1.0 13.764907441874646 -6.758293820637129 24.99870779867371 0.8575273188816467 0.8928524210523747 0.0275230682914559 0.08353885439085025 321.26942876192646 2553230.9434234216 0.026833077202597658 0.025760449599546494 1.7446414216022873e-07 6.758293820637129 0.03532510217072804 REEAAVDAQQQK ddPTM_PC-9_Lapatinib_30min_R1 2 REEAAVDAQQQK 12 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 110.31 0.00076473 4731600.0 29092.0 30191.0 32645.0 30991.0 39061.0 31174.0 31219.0 31946.0 30854.0 29405.0 False True 28677.142745180587 30121.094594429516 29961.05411334415 33270.18152294534 36763.508776880735 29840.760690143343 32835.36706425985 33430.32778460671 27378.897612976223 34487.615070300366 0.8315200307914717 0.8733887377549874 0.8687482173606622 0.9646993987588478 1.0659916234260076 0.8652601993299691 0.9520915551083329 0.969342986357901 0.7938762235998759 1.0 15.073790744787287 -5.697349973364338 6.059137422489313 0.9451955113858403 0.8578025224779128 0.24413422535460672 0.06992374180312641 0.3010366082536989 20.730354978868995 0.019105448315197775 0.03315657185070011 2.007474450482732e-06 5.697349973364338 -0.08739298890792757 REEDEENDNDNES(ph)DHDEADS ddPTM_PC-9_AZD4547_30min_R2 1 REEDEENDNDNESDHDEADS 20 1 H0YBP8;Q9NRG0 H0YBP8 CHRAC1 Chromatin accessibility complex protein 1 1 REEDEENDNDNES(0.987)DHDEADS(0.013) 76.04899999999999 0.0010184 1580000.0 2364.3 5130.5 6253.1 7708.2 5496.8 4282.7 5119.5 5735.6 5295.6 5447.3 True False 3116.098219504981 6788.833792604278 6170.179808297041 5931.193580502846 4733.664201674561 4014.9020919780314 5575.125582214366 4849.2948109761455 5575.514604818328 5256.591685029082 0.5927982248230759 1.2914896570603083 1.173798571015109 1.128334467635188 0.9005196685061476 0.7637842793482672 1.0605970401110811 0.9225169276105409 1.0606710467350065 1.0 12.359911960058513 -6.264746054657587 24.607083814236475 0.9435582570017718 1.0731822127029131 0.049515906867109605 0.18889289068103715 589.6076428998321 4387635.719824076 0.05706151541575758 0.0674240697553123 5.435680795610512e-07 6.264746054657587 0.12962395570114138 REEDEENDNDNES(ph)DHDEADS ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 REEDEENDNDNESDHDEADS 20 1 H0YBP8;Q9NRG0 H0YBP8 CHRAC1 Chromatin accessibility complex protein 1 1 REEDEENDNDNES(0.875)DHDEADS(0.125) 54.656000000000006 0.011000000000000001 3153700.0 1252.5 3049.4 3926.4 3327.7 3258.3 2727.1 4003.5 2306.7 3255.5 1241.8 True False 1464.5235119973818 3352.1242792174785 4020.020266954919 3141.2597575489613 2619.8595049022574 2584.0860752148265 3624.259497170037 2246.151569150674 3303.1055286990886 1466.9285099166088 0.9983605213867145 2.285131317959072 2.7404336610674007 2.1413857160138865 1.7859489996899642 1.7615623786340653 2.4706449378204987 1.5311936157532051 2.2517154083308815 1.0 10.518582848310103 -6.255503956447168 23.38502765269495 1.858329844862407 2.1086784993066696 0.03207238725295802 0.552463494920853 767.6619072834615 3024507.1674096207 0.16321534781136143 0.2047764416762191 5.552595586506985e-07 6.255503956447168 0.2503486544442626 REEDEPEER ddPTM_PC-9_AZD4547_30min_R2 2 REEDEPEER 9 1 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 0 ; 107.83 0.0015668 3945800.0 5913.1 5786.5 21446.2 21694.3 19294.4 20828.4 12779.7 21691.8 16416.2 17323.6 False True 7793.342799879416 7656.8729638251025 21161.80937530184 16693.014308593803 16615.705605586816 19525.996855384517 13917.068542440653 18339.830737975513 17283.92681766347 16717.106036893467 0.46618970907285395 0.4580262245706241 1.2658775585079876 0.9985588577205591 0.993934331032963 1.1680249447656805 0.8325046519251998 1.0970697139505372 1.0339066330930167 1.0 14.029037498045644 -5.2478621968456185 24.994103767101347 1.0449900890963792 0.4621078404857714 0.8225813847479925 0.10896515850953646 287.2730645673205 528836.0816676944 0.026677020532195186 0.06974050035604001 5.651162597278622e-06 5.2478621968456185 -0.5828822486106078 REEDEPEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 REEDEPEER 9 1 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 0 ; 94.69200000000001 0.0035851 4745100.0 14747.8 17366.8 60489.0 44794.0 77210.0 77702.0 39322.0 49739.0 58888.0 35119.0 False True 17244.311257672627 19090.86113081726 61931.28716580995 42284.337404107435 62081.254756622606 73627.17033344666 35597.13549337333 48433.40395282671 59749.12559484929 41485.796698148944 0.41566783405757884 0.46017824533351853 1.4928310914798766 1.0192485324982108 1.4964460055649025 1.774756089877185 0.8580559691881641 1.1674695391588745 1.440230882621937 1.0 15.340329871660698 -5.2515186048510945 23.97386435431921 1.287967514329101 0.43792274353710814 0.6186367015204375 0.264773329114598 250.24588407306297 604720.9550327386 0.068137498523636 0.17526618612935918 5.603784106575828e-06 5.2515186048510945 -0.8500447707919928 REEDEPEER ddPTM_PC-9_Lapatinib_30min_R1 1 REEDEPEER 9 1 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 0 94.69200000000001 0.0035851 1733700.0 1143.6 3044.3 3128.7 2078.5 1139.6 2976.5 1996.8 1126.7 2288.0 967.46 False True 1127.2920542894446 3037.251110391233 2871.470363131255 2231.3598236727403 1072.5709685398044 2849.202033560393 2100.1845335825615 1179.0505952205722 2030.3013462918777 1134.6841719405822 0.9934853082170916 2.6767370035635594 2.5306340161776926 1.9665029960333187 0.9452594784198414 2.51100888160586 1.8508978846428623 1.039100239852745 1.789309656818051 1.0 10.148075078230134 -8.118797544690826 0.49894880740597525 1.010416739325116 2.05193289627766 0.17274326966537001 0.6026241760068967 1.4941822826344455 0.9419044629869139 0.6601091078067253 0.3838024719332276 7.606808013073297e-09 8.118797544690826 1.041516156952544 REEDEPEERS(ph)GDETPGSEVPGDK ddPTM_PC-9_AZD4547_30min_R2 1 REEDEPEERSGDETPGSEVPGDK 23 2 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 REEDEPEERS(0.995)GDET(0.002)PGS(0.003)EVPGDK 58.711999999999996 0.018611000000000003 48971000.0 31051.0 31547.0 32635.0 29636.0 27653.0 38940.0 27670.0 34348.0 34984.0 28101.0 True False 40924.572099077544 41743.950814791366 32202.23857666979 22803.878071635703 23813.858275525134 36505.07564424885 30132.576396107313 29040.305838518827 36833.18281874847 27117.192543278714 1.5091743746614779 1.5393905821249203 1.1875211095424205 0.8409380150707337 0.878183028627263 1.346196719516122 1.1111982314546789 1.0709185986776044 1.3582963192064648 1.0 14.726920202804418 -5.333381049506895 4.209365470640487 1.0883677219386347 1.5273340156114257 0.535478799146971 0.16011519505078675 0.16595260632596692 5.631198141908117 0.04475227453985694 0.1024733529226167 4.641078887709579e-06 5.333381049506895 0.43896629367279094 REEEEQQEGGFAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 REEEEQQEGGFASPR 15 1 A0A087WTW0;A0A087WVR3;Q96T88;Q96T88-2;A0A087WWG9 A0A087WTW0 UHRF1 E3 ubiquitin-protein ligase UHRF1 1 REEEEQQEGGFAS(1)PR 113.81 8.5083e-05 5310600.0 13691.0 13802.0 18535.0 14692.0 14091.0 11991.0 12240.0 10753.0 13621.0 11182.0 True False 13495.763829378096 13770.04231699235 17011.123847169063 15772.498691075252 13262.195083971908 11478.172882386247 12873.727309220043 11252.623635756465 12086.859544511224 13114.793800921565 1.0290488767295571 1.0499625480977628 1.2970942666268765 1.2026493843896298 1.0112393138075861 0.8752080327469339 0.981618735653733 0.8580099547555031 0.9216202502293167 1.0 13.678907504367254 -6.473247570067147 4.261351796965093 0.9227185099620643 1.1472924171205605 0.6160634897402628 0.08076218013211303 0.15262175424119742 5.844947082750617 0.027934814793872796 0.03080594192150888 3.36319795235425e-07 6.473247570067147 0.22457390715849623 REEGDPS(ph)PHSGGVCKPK ddPTM_PC-9_AZD4547_30min_R2 1 REEGDPSPHSGGVCKPK 17 2 O75376-2;O75376;E7EVK1;J3KRE4 O75376-2;J3KRE4 NCOR1 Nuclear receptor corepressor 1 1 REEGDPS(1)PHSGGVCKPK 63.29 0.008305100000000001 4919500.0 59232.0 47471.0 65936.0 85876.0 70618.0 60915.0 51156.0 65633.0 59514.0 75551.0 True False 78066.54389786367 62815.0724039992 65061.64555818289 66078.61497097403 60813.90965540931 57105.97542037545 55708.78489769663 55490.92794629985 62659.78853976097 72905.98248593464 1.0707837853076683 0.861590095382334 0.892404756643049 0.9063538096303992 0.8341415557652188 0.7832824340772391 0.7641181559886971 0.7611299656651005 0.8594601760129847 1.0 16.15374958297224 -1.5228787802334522 0.7654610355522168 0.8254216535251924 45.70363304216455 0.4414234298675519 0.0712869781884743 360.49029552757804 1.4574399598079262 0.025964847217651577 27949.836574997487 0.029999997585524473 1.5228787802334522 44.87821138863936 REEGDPS(ph)PHSGGVCKPK ddPTM_PC-9_Lapatinib_30min_R1 1 REEGDPSPHSGGVCKPK 17 2 O75376-2;O75376;E7EVK1;J3KRE4 O75376-2;J3KRE4 NCOR1 Nuclear receptor corepressor 1 1 REEGDPS(0.996)PHS(0.004)GGVCKPK 43.592 0.040523 3384500.0 41808.0 30296.0 34713.0 31693.0 33687.0 36823.0 27088.0 25351.0 38738.0 27492.0 True False 41211.81025335179 30225.851473380695 31859.031136054997 34023.808944748685 31705.596891190235 35248.16612860553 28490.48409739807 26528.90000837555 34374.91851077569 32243.95556921265 1.2781251408466112 0.9374113981921346 0.9880621212142723 1.0551995976956217 0.9833035783445734 1.0931712783484102 0.8835914699188308 0.8227557549950857 1.0660887569141095 1.0 14.976741118763824 -7.262743520650707 24.999556825917697 0.928338640443438 1.0440816385694158 0.2034913873936811 0.10619838423893581 189.61602481504983 3634761.022816256 0.04158396282143754 0.02973911986593314 5.460802620598407e-08 7.262743520650707 0.11574299812597788 REEGPPPPSPDGAS(ph)SDAEPEPPSGR ddPTM_PC-9_Lapatinib_30min_R1 1 REEGPPPPSPDGASSDAEPEPPSGR 25 1 Q9NTJ3;C9JWF0;C9IYK2;C9JJ64;C9JR83;E9PD53;Q9NTJ3-2;F8WCB7 Q9NTJ3 SMC4 Structural maintenance of chromosomes protein 4;Structural maintenance of chromosomes protein 1 REEGPPPPS(0.004)PDGAS(0.493)S(0.493)DAEPEPPS(0.009)GR 92.07 2.064e-06 11036000.0 24297.0 28616.0 26675.0 23536.0 26114.0 21251.0 27022.0 27084.0 23388.0 23120.0 True False 23950.520324475914 28549.74141016179 24481.884468477736 25266.91595379437 24578.02586209937 20342.144268500553 28421.06694033853 28342.421515003072 20753.797153441643 27116.261194536477 0.8832530470425468 1.0528642280490401 0.9028488217029887 0.9317994015666613 0.9063943471326156 0.7501824872744327 1.0481189400131958 1.04521863510865 0.7653635213405904 1.0 14.726870652126035 -10.494496207587348 15.025459974634801 1.0000039232798492 0.9263399161335221 0.04880347885316827 0.1023481621406499 0.0 0.0 0.09803609468823357 0.023777245501331857 3.2026080608105146e-11 10.494496207587348 -0.07366400714632715 REELFIVSK ddPTM_PC-9_AZD4547_30min_R2 2 REELFIVSK 9 1 P15121;E9PCX2;E9PEF9 P15121 AKR1B1 Aldose reductase 0 ; 129.88 0.00081239 11755300.0 93708.0 63764.0 119068.0 110627.0 105817.0 103274.0 144728.0 188329.0 108073.0 120774.0 False True 123505.19475251526 84374.4660270187 117489.08052235097 85123.654320112 91126.13608437579 96816.26045413855 157608.5116247131 159227.08041989055 113785.51814459755 116545.73902074479 1.0597143730027891 0.7239601098758343 1.0080941740945009 0.730388386871529 0.7818916148290553 0.8307147156783273 1.3523318222441343 1.3662196641230153 0.9763164153461164 1.0 16.83053673410725 -7.247697369584693 24.389509108279704 1.2042352767586084 0.8476647188561601 0.4920098347132462 0.1569086529761859 422.77382292295295 750345.8725530125 0.0583976892740414 0.04497029923009579 5.6533077832576195e-08 7.247697369584693 -0.3565705579024483 REELFIVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 REELFIVSK 9 1 P15121;E9PCX2;E9PEF9 P15121 AKR1B1 Aldose reductase 0 ; 131.83 0.00077275 9702200.0 102059.0 84527.0 103852.0 115911.0 146811.0 112769.0 120554.0 108954.0 95692.0 96528.0 False True 119335.57294286691 92918.28194051833 106328.22554090327 109416.88245853205 118044.43844158147 106855.19512152114 109134.2523846228 106094.07294630527 97091.31446852174 114027.7622847727 1.046548406736585 0.814874203252927 0.9324766478829899 0.95956353317953 1.0352254229700442 0.9370980626162004 0.9570849256172469 0.9304231778340625 0.8514708394087932 1.0 16.79902559386531 -4.4447816258089405 21.68046513679114 0.9372924533211704 6.437050367890615 0.23146806375026596 0.06069006507962157 518.0799601371104 147285.33513058792 0.014833238770914062 3355.1517181328904 3.591024550044395e-05 4.4447816258089405 5.499757914569445 REELFIVSK ddPTM_PC-9_Lapatinib_30min_R1 2 REELFIVSK 9 1 P15121;E9PCX2;E9PEF9 P15121 AKR1B1 Aldose reductase 0 ; 135.8 0.00065692 11684200.0 98712.0 101478.0 118273.0 119105.0 116010.0 106834.0 104541.0 102164.0 110578.0 99078.0 False True 97304.34877843625 101243.03392578992 108549.05048698293 127864.37902263255 109186.51988443559 102264.95886221754 109953.62145695854 106910.91240801862 98123.54120203824 116203.5002868633 0.8373615987317761 0.871256319094162 0.9341289222701177 1.1003487735479816 0.9396147242974145 0.8800505889217047 0.9462160880311167 0.9200317730885496 0.8444112351160477 1.0 16.826294000756214 -1.5237200733627703 0.00649916342616516 1.7858898862880317 8.769251277957825e-07 0.05265399180194785 0.07294876078474942 151638.34341889728 76.5264228715458 9548.355430101396 11569.97217872489 0.029941939371511146 1.5237200733627703 -1.7858890093629038 REELITNWEQIR ddPTM_PC-9_AZD4547_30min_R2 1 REELITNWEQIR 12 1 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 130.69 8.775100000000001e-05 2951400.0 8179.5 7896.0 10340.0 14896.0 12317.0 10827.0 11232.0 10550.0 9372.5 11654.0 False True 10780.410855830885 10448.227585304237 10202.884843964024 11461.95734090584 10606.997156895939 10149.985978435609 12231.62624073283 8919.739914882188 9867.911215662021 11245.99700720153 0.9585998332497777 0.9290619211985892 0.9072459149180341 1.0192033070581485 0.9431797954510927 0.9025421198259189 1.08764267257942 0.7931479893841612 0.8774598827781093 1.0 13.457123947609087 -7.782533906317649 24.999998726073592 0.8764780484309014 0.9593715928666833 0.17818720995670478 0.07025953173805578 368.8776075209223 437165.85159572255 0.03650503244234282 0.017563538355437537 1.6499321824867677e-08 7.782533906317649 0.0828935444357819 REELITNWEQIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 REELITNWEQIR 12 1 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 104.59 0.0011972 2621300.0 8346.0 8178.9 8004.2 8843.1 8441.2 9158.0 9409.2 7048.0 8551.5 7057.8 False True 9758.81295898614 8990.847139532974 8195.050484097543 8347.649776717022 6787.207455661218 8677.738358262386 8517.892459291199 6862.99746797328 8676.549509651439 8337.32327048594 1.1704971298800735 1.0783853339788927 0.9829354360179313 1.00123858772127 0.8140751216505997 1.0408302613119864 1.0216579330016473 0.8231655706896047 1.040687667751394 1.0 13.025368559910337 -4.981089893724752 1.4701184314625007 0.9551582051496209 1.2121374208664981 0.42624152417599936 0.07764182410018546 0.7391926232614479 1.952916724527508 0.02219973035499894 0.25077442177359194 1.0445039971021658e-05 4.981089893724752 0.2569792157168772 REELITNWEQIR ddPTM_PC-9_Lapatinib_30min_R1 1 REELITNWEQIR 12 1 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 151.66 0.00012057 3423200.0 7903.2 10349.0 10758.0 8864.8 9149.5 8073.7 8624.1 9323.3 10570.0 6934.8 False True 7790.498918730626 10325.037526340659 9873.518767080915 9516.746964105898 8611.3443986091 7728.406671713939 9070.613699954622 9756.494554380011 9379.495292965541 8133.470939959837 0.957832022298846 1.269450349372201 1.21393668705106 1.170072043578592 1.0587539393915415 0.9501978587941082 1.1152205210927344 1.1995487076060285 1.1531971236147132 1.0 12.98965543514739 -6.251222747999354 23.171292017361026 1.0847860775702796 1.1655186111504054 0.10688692677077005 0.10052745897989038 598.003884058189 1356266.270498381 0.031003612338497896 0.0395130764134385 5.607602904274864e-07 6.251222747999354 0.08073253358012589 REEMVNYFAR ddPTM_PC-9_AZD4547_30min_R2 1 REEMVNYFAR 10 1 Q5VZE5 Q5VZE5 NAA35 N-alpha-acetyltransferase 35, NatC auxiliary subunit 0 53.123999999999995 0.04015 13751000.0 4595.8 4724.7 7797.2 8261.2 9761.9 5292.8 4873.2 6053.7 4528.6 7312.3 False True 6057.168801421552 6251.866878455792 7693.804033400029 6356.707974267672 8406.62868765953 4961.840379298415 5306.905359360686 5118.239765186949 4767.972550679864 7056.298602690899 0.8584059635899859 0.8859980608065057 1.0903455857814774 0.9008558639856256 1.1913652129820138 0.7031789127243329 0.752080610270222 0.7253434205909487 0.675704476120329 1.0 12.784695897641742 -6.791862325120636 24.998789777880862 0.7528965485925274 0.9810063689646618 0.4182896488900132 0.1252749076698474 186.20074822799526 153001.42402274086 0.042479487693146446 0.0374676616203301 1.6148704027308753e-07 6.791862325120636 0.22810982037213434 REEPEALY(ph)AAVNK ddPTM_PC-9_Lapatinib_30min_R1 1 REEPEALYAAVNK 13 1 A0A087WVF7;Q9NZM3-4;Q9NZM3-3;Q9NZM3-2;Q9NZM3 A0A087WVF7 ITSN2 Intersectin-2 1 REEPEALY(1)AAVNK 137.81 0.00041656 4023800.0 13031.0 20274.0 24972.0 19542.0 22120.0 23922.0 29589.0 27724.0 25495.0 20564.0 True False 12845.17555040727 20227.05679863085 22918.89855470762 20979.183870200974 20818.945089593246 22898.91182490565 31120.973639911095 29012.158251437944 22623.484625748017 24118.460000192394 0.5325868878155904 0.8386545740677264 0.9502637628822401 0.8698392795408008 0.8631954564854959 0.9494350727502081 1.290338339996121 1.2029026003818866 0.9380153055198196 1.0 14.55785017148832 -6.982242207907346 3.6200733639504 1.1258976974097186 0.8249438025976491 0.5008307792672699 0.13819750183673493 0.19963003176939628 5.640331380479292 0.05447955117463072 0.045191721605454246 1.0417362865313975e-07 6.982242207907346 -0.30095389481206947 REESPMDVDQPS(ph)PSAQDTQSIASDGTPQGEK ddPTM_PC-9_AZD4547_30min_R2 6 REESPMDVDQPSPSAQDTQSIASDGTPQGEK 31 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 REESPMDVDQPS(0.5)PS(0.5)AQDTQSIASDGTPQGEK;REESPMDVDQPS(0.494)PS(0.494)AQDT(0.011)QSIASDGTPQGEK;REESPMDVDQPS(0.498)PS(0.498)AQDT(0.004)QSIASDGTPQGEK;REESPMDVDQPS(0.71)PS(0.29)AQDTQSIASDGTPQGEK;REESPMDVDQPS(0.793)PS(0.204)AQDT(0.003)QSIASDGTPQGEK;REESPMDVDQPS(0.491)PS(0.491)AQDT(0.013)QS(0.002)IAS(0.003)DGT(0.001)PQGEK 129.3 2.6346e-16 114569000.0 333290.0 324350.0 365567.0 330032.0 343627.0 407142.0 368748.0 427312.0 395532.0 375221.0 True False 439269.28713734116 429189.7944900496 360719.34272276505 253948.22134357077 295920.32248377666 381683.34637778084 401565.8576404686 361280.74905290396 416439.01402541826 362084.6269983841 1.2131674597146085 1.1853300650954315 0.9962293779580288 0.7013504645274655 0.8172683964434019 1.054127455070011 1.1090386823913976 0.9977798617076231 1.1501151470517326 1.0 18.465967400148983 -5.267742003177705 4.900754554046755 0.9689161540685944 1.203432596444278 0.33314162497890665 0.1251065011090862 0.21441506809480895 15.788591736137299 0.03685556910516987 0.08987584600051973 5.398312192170784e-06 5.267742003177705 0.2345164423756836 REESPMDVDQPS(ph)PSAQDTQSIASDGTPQGEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 REESPMDVDQPSPSAQDTQSIASDGTPQGEK 31 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 REESPMDVDQPS(0.48)PS(0.48)AQDT(0.039)QSIASDGTPQGEK;REESPMDVDQPS(0.494)PS(0.494)AQDT(0.01)QS(0.001)IAS(0.001)DGTPQGEK;REESPMDVDQPS(0.498)PS(0.498)AQDT(0.003)QS(0.001)IASDGTPQGEK;REESPMDVDQPS(0.701)PS(0.294)AQDT(0.004)QS(0.001)IASDGTPQGEK 110.03 6.0621e-16 82906000.0 160965.0 181519.0 187951.0 175931.0 188022.0 158047.0 191258.0 127033.0 163775.0 143887.0 True False 188213.19529633436 199539.00670272068 192432.46464813672 166074.15644599768 151180.43882722018 149758.73709415752 173140.65765199088 123698.5183525895 166169.89954314035 169972.57409113506 1.1073150848172666 1.1739482547092146 1.1321383210032416 0.9770644313296853 0.889440191369703 0.8810758905955064 1.0186387926275517 0.7277557512676452 0.9776277168929864 1.0 17.374942453654363 -5.859797980378284 2.9475280511306154 0.9064480313098429 1.1456031404501663 0.6133988133890953 0.07859214984014624 0.15488379886910647 2.7040005347893845 0.02219352793859125 0.03627309407378197 1.381026523687492e-06 5.859797980378284 0.23915510914032345 REESPMDVDQPS(ph)PSAQDTQSIASDGTPQGEK ddPTM_PC-9_Lapatinib_30min_R1 9 REESPMDVDQPSPSAQDTQSIASDGTPQGEK 31 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 REESPMDVDQPS(0.499)PS(0.499)AQDT(0.002)QSIASDGTPQGEK;REESPMDVDQPS(0.5)PS(0.5)AQDTQSIASDGTPQGEK;REESPMDVDQPS(0.809)PS(0.187)AQDT(0.003)QSIASDGTPQGEK;REESPMDVDQPS(0.5)PS(0.5)AQDT(0.001)QSIASDGTPQGEK;REESPMDVDQPS(0.465)PS(0.465)AQDT(0.058)QS(0.008)IAS(0.004)DGTPQGEK;REESPMDVDQPS(0.818)PS(0.177)AQDT(0.005)QSIASDGTPQGEK;REESPMDVDQPS(0.499)PS(0.499)AQDT(0.001)QSIASDGTPQGEK;REESPMDVDQPS(0.813)PS(0.187)AQDTQSIASDGTPQGEK;REESPMDVDQPS(0.5)PS(0.5)AQDTQSIASDGTPQGEK 152.64 4.557e-18 190654500.0 375000.0 466654.0 449399.0 427807.0 461569.0 481983.0 465815.0 501691.0 467927.0 388818.0 True False 369652.4312334223 465573.49133413524 412451.1489503059 459269.35390231555 434420.4188995691 461369.7106472492 489932.62144970044 525001.395373039 415224.1337702445 456024.67323258234 0.8105974367858199 1.020939257592939 0.9044491957564476 1.0071151427985967 0.9526248126447434 1.0117209390816027 1.074355512338308 1.151256557351398 0.9105299737991837 1.0 18.79875235800953 -2.998989728834301 0.4565983618681391 1.0354060333104926 5.051470591620493e-12 0.3539861739301271 0.07271155023414541 26.122148268120732 1.1441795641468377 0.045357600207758406 20.684269566903065 0.0010023289431106577 2.998989728834301 -1.0354060333054411 REESPMDVDQPS(ph)PSAQDTQSIASDGTPQGEKEK ddPTM_PC-9_AZD4547_30min_R2 1 REESPMDVDQPSPSAQDTQSIASDGTPQGEKEK 33 2 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 REES(0.003)PMDVDQPS(0.809)PS(0.155)AQDT(0.031)QS(0.002)IASDGTPQGEKEK 78.836 1.159e-07 7408700.0 53988.0 43953.0 53860.0 51646.0 58707.0 63470.0 59211.0 64684.0 56195.0 59938.0 True False 71155.06097983959 58159.94770223879 53145.781208501176 39739.81262274589 50556.54640658358 59501.21086647342 64480.66429309394 54688.57409044924 59165.35297563375 57839.58886370729 1.2302138099132889 1.0055387468138195 0.9188478385234279 0.6870694173914071 0.874082050024847 1.0287281088162912 1.114818856078587 0.9455214873556056 1.0229213958461993 1.0 15.819769676886912 -8.271622404829706 22.407846482612655 1.0114607055952969 0.9681181987144213 0.008562563877178686 0.13649950349057827 1351.3749550805223 2973577.9666339196 0.13637099407820744 0.03714747921005794 5.350293358183597e-09 8.271622404829706 -0.0433425068808756 REESPMDVDQPS(ph)PSAQDTQSIASDGTPQGEKEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 REESPMDVDQPSPSAQDTQSIASDGTPQGEKEK 33 2 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 REES(0.001)PMDVDQPS(0.479)PS(0.479)AQDT(0.031)QS(0.01)IASDGTPQGEKEK;REESPMDVDQPS(0.844)PS(0.154)AQDT(0.002)QSIASDGTPQGEKEK 105.55 2.4239e-20 15822100.0 43506.0 39939.0 40008.0 49901.0 46662.0 49869.0 49264.0 39350.0 44092.0 43825.0 True False 50870.70651733181 43903.879972344395 40961.94245118494 47105.20875122479 37518.916065969715 47253.78185064286 44597.35727952658 38317.104194771324 44736.76208613124 51770.12558149086 0.982626677952649 0.848054345613586 0.7912274113901296 0.909891722728718 0.724721364774585 0.9127615844056846 0.8614496638476626 0.740139293934235 0.8641424293188459 1.0 15.65983219737306 -5.9288011612666205 0.004505518429209714 1.697555247933142 4.547861620433554e-05 0.018384912301865453 0.08713448988242561 167039.36994139696 181.65442339493455 33507.3288359974 34936.92696893539 1.1781452557381957e-06 5.9288011612666205 -1.6975097693169376 REESPMDVDQPS(ph)PSAQDTQSIASDGTPQGEKEK ddPTM_PC-9_Lapatinib_30min_R1 3 REESPMDVDQPSPSAQDTQSIASDGTPQGEKEK 33 2 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 REESPMDVDQPS(0.413)PS(0.087)AQDT(0.087)QS(0.413)IASDGTPQGEKEK;REESPMDVDQPS(0.589)PS(0.401)AQDT(0.01)QS(0.001)IASDGTPQGEKEK;REESPMDVDQPS(0.789)PS(0.206)AQDT(0.005)QSIASDGTPQGEKEK 89.684 2.7023000000000004e-11 24384700.0 121825.0 90255.0 91397.5 80519.5 90776.9 108037.0 76163.2 77120.8 94097.1 72604.5 True False 120087.75316003109 90046.02009275062 83883.15035455266 86441.17263517808 85437.58121625218 103416.50935654769 80106.55782660034 80704.11391132214 83498.89371160907 85154.09108558504 1.4102405607187516 1.0574479622153314 0.9850748130262468 1.015114735336667 1.003329142816899 1.2144631929968908 0.9407247121701808 0.947742062447823 0.9805623270370839 1.0 16.37778822298354 -4.761857887164837 4.035948822447345 1.0138688976683006 1.4532144028683784 0.7306655570469378 0.07226753046247847 0.13238539434663713 4.076089110918471 0.018924196566089492 0.17530196017420763 1.7303824942748373e-05 4.761857887164837 0.43934550520007787 REESPMDVDQPSPS(ph)AQDTQSIASDGTPQGEKEK ddPTM_PC-9_AZD4547_30min_R2 1 REESPMDVDQPSPSAQDTQSIASDGTPQGEKEK 33 2 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 REESPMDVDQPS(0.266)PS(0.683)AQDT(0.049)QS(0.002)IASDGTPQGEKEK 93.679 1.1366e-12 9499300.0 42412.0 27167.0 41209.0 36724.0 41729.0 45131.0 40758.0 42909.0 40263.0 41196.0 True False 55898.1337755975 35948.201470359716 40662.54173451774 28257.849180144058 35935.64864497121 42308.95143555714 44385.383041291716 36278.40000072796 42391.21998145637 39753.74057908648 1.406110040497779 0.9042721753150251 1.0228607708908117 0.7108223973018996 0.9039564106799077 1.0642759855864958 1.1165083434850867 0.9125782749564247 1.0663454397988754 1.0 15.278802994940177 -4.756748014384157 24.98357591712316 0.9636206614978601 1.4061107142762368 0.5862654548838723 0.1106732857011704 106.83823780773642 568891.9424141309 0.028950871759015173 0.2278307487919651 1.750862276338102e-05 4.756748014384157 0.4424900527783767 REFEER ddPTM_PC-9_AZD4547_30min_R2 1 REFEER 6 1 P25325-2;B1AH49;P25325 P25325-2 MPST 3-mercaptopyruvate sulfurtransferase;Sulfurtransferase 0 79.939 0.032782 4919600.0 6589.6 7090.2 10759.0 14259.0 11687.0 9702.5 7343.9 12380.0 7006.5 9755.5 False True 8684.955727805269 9381.96849358208 10616.328630194283 10971.807849353941 10064.461782304363 9095.801141199912 7997.492872980574 10466.955464098726 7376.849285946755 9413.962914343105 0.9225610730389514 0.9966013865731 1.1277215267142442 1.1654823743396423 1.0690993658972416 0.9662032051710718 0.8495352006109566 1.1118543337526094 0.7836072176051804 1.0 13.200586454302949 -6.824771790604797 4.944400286763279 0.9412018368840454 1.063104216334954 0.23787274920149737 0.10240318926947785 0.3088091717594588 14.768823601487226 0.03673777551324601 0.03279396879619325 1.4970220919727595e-07 6.824771790604797 0.12190237945090865 REFEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 REFEER 6 1 P25325-2;B1AH49;P25325 P25325-2 MPST 3-mercaptopyruvate sulfurtransferase;Sulfurtransferase 0 ; 79.939 0.032782 5628000.0 18566.5 20365.0 23753.0 20587.0 26856.0 26219.0 21015.0 18140.5 22764.0 16150.0 False True 21709.441744909676 22386.702612403737 24319.36160375412 19433.577133954535 21593.75958740908 24844.029484088416 19024.307064575576 17664.33109644852 23096.880434743078 19077.86715667034 1.1379386158121578 1.1734384367267439 1.2747421608526692 1.0186451648060577 1.1318749318295305 1.3022435516541484 0.9971925534623487 0.9259070183991928 1.2106636577908836 1.0 14.219612271307447 -7.2938094047010615 24.884715946712298 1.0272663675294782 1.1688795442042483 0.31894371078590256 0.09973308296468159 775.9581386680617 596520.8915352502 0.04144784095942127 0.02794669470780434 5.0838250331889626e-08 7.2938094047010615 0.14161317667477014 REFEER ddPTM_PC-9_Lapatinib_30min_R1 2 REFEER 6 1 P25325-2;B1AH49;P25325 P25325-2 MPST 3-mercaptopyruvate sulfurtransferase;Sulfurtransferase 0 ; 97.473 0.022026 7325600.0 18879.1 11642.2 15101.5 11989.8 12604.900000000001 17614.7 11648.3 12633.7 15659.5 10848.900000000001 False True 18609.88057199707 11615.243201194642 13859.912963475772 12871.569888800297 11863.50456418689 16861.36034287124 12251.391978430365 13220.707823589373 13895.76220815458 12724.117909749422 1.4625674411377374 0.9128525280557843 1.089263166357181 1.0115883851514684 0.9323636143843718 1.3251496459296246 0.9628480390804264 1.0390274530118473 1.0920805911038771 1.0 13.63527802552903 -4.749993013819999 24.999878086856505 1.0454925215619109 1.4625683559631857 0.5658971865243168 0.11080477068845199 378.0868305335416 825722.9801687475 0.02665515470675626 0.41025071610144825 1.778308016158713e-05 4.749993013819999 0.4170758344012748 REGGDGEEQDVGDAGR ddPTM_PC-9_AZD4547_30min_R2 2 REGGDGEEQDVGDAGR 16 1 Q8N1G4 Q8N1G4 LRRC47 Leucine-rich repeat-containing protein 47 0 ; 147.75 3.6995999999999997e-06 7823400.0 23649.2 22532.0 33089.0 52670.0 43571.0 37685.0 29019.0 47664.0 30703.0 38938.0 False True 31169.15366608178 29815.02836272481 32650.21824003147 40527.74524338818 37521.918740205634 35328.550992643 31601.634782748024 40298.62400975779 32325.897898583204 37574.79247180479 0.8295229757947528 0.7934848445296746 0.8689394163529021 1.0785886648289333 0.9985928403559693 0.9402194574767829 0.8410328495216873 1.072490926995722 0.8603080888028796 1.0 15.197477515607925 -5.534431186973768 23.94315861376535 0.9682139860435282 0.8164309395205829 0.4420133631509754 0.07368162462210599 112.0323303865794 232192.85311552088 0.019766702398899175 0.034279519168895226 2.921250589409583e-06 5.534431186973768 -0.15178304652294528 REGGDGEEQDVGDAGR ddPTM_PC-9_Lapatinib_30min_R1 2 REGGDGEEQDVGDAGR 16 1 Q8N1G4 Q8N1G4 LRRC47 Leucine-rich repeat-containing protein 47 0 ; 178.22 4.631e-06 5910800.0 27659.0 25243.1 27499.0 25561.0 18794.6 22753.3 20548.1 24594.4 28371.0 21145.9 False True 27264.5775879606 25184.651152881434 25238.13836920971 27440.841208996368 17689.138579605293 21780.19439953289 21611.980075374515 25737.14561027143 25175.55922012539 24800.94063985936 1.099336431786049 1.015471611282573 1.0176282720764107 1.1064435662933783 0.713244664243735 0.8782003358585677 0.8714177574636165 1.0377487686457918 1.0151050149954375 1.0 14.59810721914245 REGPGS(ph)EPDSQVDGGLSGASLGEK ddPTM_PC-9_Lapatinib_30min_R1 1 REGPGSEPDSQVDGGLSGASLGEK 24 1 Q5JSZ5;A0A494C0D3;A0A494C065;H0Y412 Q5JSZ5 PRRC2B Protein PRRC2B 1 REGPGS(0.999)EPDS(0.001)QVDGGLSGASLGEK 81.48899999999999 4.4166000000000004e-05 14959000.0 32403.0 35169.0 41735.0 34095.0 40782.0 40267.0 33761.0 29692.0 38446.0 30137.0 True False 31940.92727801757 35087.5683412769 38303.70940175887 36602.460037585806 38383.28294049693 38544.87427696164 35508.97938615829 31071.598715975153 34115.80662567202 35346.1402949717 0.9036609658498257 0.9926845773955244 1.083674457298748 1.035543336051117 1.085925722587518 1.090497405241301 1.004606983671418 0.8790662419340695 0.9651918523767443 1.0 15.10926506470241 -7.5363945585510805 22.14797906832753 0.9416445572982973 1.036203830073385 0.2834847574616205 0.059170406609436614 73.20346236904 119950.19210492616 0.028985270511273108 0.01675549946925702 2.9080739189259874e-08 7.5363945585510805 0.09455927277508758 REGPVGGES(ph)DSEEMFEK ddPTM_PC-9_AZD4547_30min_R2 3 REGPVGGESDSEEMFEK 17 1 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;J3QL92 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 REGPVGGES(0.986)DS(0.014)EEMFEK;REGPVGGES(0.991)DS(0.009)EEMFEK;REGPVGGES(0.968)DS(0.032)EEMFEK 117.65 0.00011852 21332400.0 90956.0 78833.0 103949.0 136663.0 133094.0 117934.0 109839.0 128504.0 104968.0 124795.0 True False 119878.11599767128 104314.22558666265 102570.56834093008 105157.45677230232 114616.19546966862 110559.56833664227 119614.45821366215 108646.65952815357 110516.3941835808 120425.96503464153 0.9954507399063595 0.8662104186306981 0.8517313380999256 0.8732124898650628 0.9517565039790075 0.9180708521192992 0.9932613633551042 0.9021863308041622 0.9177123401235758 1.0 16.87778695945876 -6.267873771979091 24.80423949010788 0.9431240373427138 0.8912683365550002 0.21066790676567038 0.04705690113414039 735.799175119248 2836462.402658745 0.014488554311380885 0.016819512142125913 5.396674544777525e-07 6.267873771979091 -0.05185570078771362 REGPVGGES(ph)DSEEMFEK ddPTM_PC-9_Lapatinib_30min_R1 1 REGPVGGESDSEEMFEK 17 1 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;J3QL92 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 REGPVGGES(0.954)DS(0.046)EEMFEK 93.196 0.00071379 16057000.0 57847.0 48717.0 56828.0 48312.0 50306.0 50301.0 39495.0 44550.0 51076.0 48265.0 True False 57022.09117215942 48604.198779663544 52155.82120242366 51865.02564410749 47347.099985401364 48149.74348735807 41539.85784948084 46619.95563777088 45323.28302587587 56607.54094093003 1.0073232333420379 0.8586170317905529 0.9213581854200003 0.9162211391275351 0.8364097644659758 0.8505888559547629 0.7338219812944654 0.8235644026017453 0.8006580443614522 1.0 15.78870663319694 -6.290628910321005 2.7055441106374656 0.824682486355852 0.9230262896972192 0.23575678780754772 0.07179153613436466 0.3641708911542013 5.297090370469279 0.022467294559672932 0.02770621982357027 5.121192368935826e-07 6.290628910321005 0.09834380334136728 REGPVGGESDS(ph)EEMFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 REGPVGGESDSEEMFEK 17 1 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;J3QL92 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 REGPVGGES(0.04)DS(0.96)EEMFEK 51.611000000000004 0.027308 6067900.0 28299.0 20988.0 32080.0 28924.0 33528.0 25412.0 35233.0 32495.0 28175.0 24707.0 True False 33089.46176927258 23071.54993514019 32844.90886407751 27303.48205287322 26958.429082761853 24079.349984730725 31895.475175169708 31642.040681298473 28587.006073136814 29186.183519495615 1.1337371927086553 0.7904956096684923 1.1253581285178296 0.9354933999724631 0.9236709234269812 0.8250256484766617 1.092827883915153 1.0841445117400297 0.9794705105599516 1.0 14.832997951216145 -7.309573280576722 24.9983865960306 1.046122764172944 0.9534706235992044 0.12405835477308202 0.10793906349053675 787.6595103777111 409068.71142316295 0.04331864432680184 0.029205489551736262 4.902602918578668e-08 7.309573280576722 -0.0926521405737396 REGPVGGESDS(ph)EEMFEK ddPTM_PC-9_Lapatinib_30min_R1 1 REGPVGGESDSEEMFEK 17 1 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;J3QL92 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 REGPVGGES(0.328)DS(0.672)EEMFEK 57.986000000000004 0.016273 18529000.0 118020.0 94657.0 114100.0 93040.0 106870.0 102790.0 103460.0 92802.0 114560.0 83552.0 True False 116337.01315778292 94437.82753220892 104719.13843873693 99882.47197234145 100584.1167145041 98393.91131519333 108816.65256633202 97113.91971035718 101657.0464297193 97993.851873958 1.187186858492085 0.9637117607508384 1.0686296786601384 1.019272842757652 1.0264329321790284 1.0040824953156233 1.1104436705508276 0.991020537036011 1.0373818814722477 1.0 16.580403617050834 -4.746683244862202 24.953443115194336 1.0275878020907174 1.1871872864917845 0.6056337940996954 0.03930246349787082 513.3987007005153 868136.0001091089 0.009158623616718846 0.20150856168050957 1.7919123189278073e-05 4.746683244862202 0.15959948440106708 REGS(ph)YDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 REGSYDR 7 1 Q9HCD5;Q5JY17 Q9HCD5 NCOA5 Nuclear receptor coactivator 5 1 REGS(0.998)Y(0.002)DR;REGS(0.998)Y(0.002)DR 61.593 0.032263 29600000.0 8220.5 19169.3 15219.3 11540.0 42057.0 37475.0 11105.5 24507.0 36958.0 51899.0 True False 9612.068287724125 21072.301418509764 15582.185831516668 10893.451213184799 33816.232758700615 35509.74502903289 10053.506643142713 23863.71721731287 37498.44083233328 61307.87786774202 0.15678357532550719 0.34371278457832977 0.2541628641123696 0.17768436279404376 0.5515805461681702 0.5792036238089532 0.16398392821279667 0.3892438956832511 0.6116414747420837 1.0 15.90378484711129 -14.522878745208773 0.14725304580701037 3.3412112770647067 0.14512378868054257 0.693712939704832 0.14039284832470092 82.72126520108748 0.7271560643707501 56.283387182679704 0.7920132763441304 3.0000000004943482e-15 14.522878745208773 -3.196087488384164 REGS(ph)YDR ddPTM_PC-9_Lapatinib_30min_R1 2 REGSYDR 7 1 Q9HCD5;Q5JY17 Q9HCD5 NCOA5 Nuclear receptor coactivator 5 1 REGS(1)YDR;REGS(0.999)Y(0.001)DR 68.626 0.022298 49378000.0 11646.9 23145.1 11130.5 19876.4 22020.8 13718.8 39947.0 42538.0 22127.3 26797.8 True False 11480.81307022012 23091.508942980716 10215.39325497249 21338.176761726674 20725.57983855854 13132.078904084761 42015.260197827854 44514.47077260378 19635.090463201162 31429.764024176024 0.36528473651246596 0.7347019508392918 0.3250229065389969 0.6789162255660965 0.6594252448925885 0.41782301941508254 1.3367984616591262 1.4163157807472846 0.6247291722616083 1.0 14.93984381991936 -7.256508099003683 24.999760903997352 1.129153842571632 0.5427994690426743 0.5751420941603684 0.236688924457225 287.0962796029171 1455475.8292717657 0.09001147592478988 0.06749082120603815 5.5397721291780084e-08 7.256508099003683 -0.5863543735289578 REPAEQPGDGER ddPTM_PC-9_AZD4547_30min_R2 1 REPAEQPGDGER 12 1 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 0 75.479 0.012466 2666200.0 6671.9 6266.7 9957.7 11117.0 9142.7 8627.3 7007.9 8542.9 8092.9 9572.0 False True 8793.425415858934 8292.288223002288 9825.654391754406 8554.14740593785 7873.393919489523 8087.833567170726 7631.589523898827 7222.791101312519 8520.674172017196 9236.887193490053 0.9519901273728166 0.8977362231777068 1.0637408670184154 0.9260855120074021 0.8523860641102677 0.8756016391399526 0.8262079382410773 0.7819507751922072 0.9224616468221429 1.0 13.173191033800265 -6.078862050984289 4.762959078772277 0.8638234598334552 0.9682964895639099 0.2753848139357864 0.06701823539936569 0.2506674307020819 10.223299677055236 0.01949206791153893 0.02592961978183487 8.339460366283475e-07 6.078862050984289 0.10447302973045469 REPAEQPGDGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 REPAEQPGDGER 12 1 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 0 130.69 8.775100000000001e-05 2323100.0 5183.3 6826.0 9036.1 7183.3 7893.9 7618.1 8866.0 9183.1 7439.0 6928.8 False True 6060.730315158503 7503.640168537583 9251.554893600078 6780.842989572819 6347.146961835292 7218.593425101414 8026.148295718626 8942.053355298727 7547.781301794667 8184.936591649374 0.7404737040164638 0.9167621623597085 1.130314791080839 0.8284539426354173 0.7754668458043921 0.8819363893992942 0.9805999357291599 1.092501237507667 0.9221551342859808 1.0 12.998755524908573 -7.336179158088448 4.462544985889145 1.009971942185789 0.8850072682904246 0.23475985991033443 0.10590043918459069 0.3727769795161093 14.044395635731197 0.04880808718629948 0.03242323432103216 4.611273079712384e-08 7.336179158088448 -0.12496467389536425 REPAEQPGDGER ddPTM_PC-9_Lapatinib_30min_R1 2 REPAEQPGDGER 12 1 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 0 ; 105.66 0.0011164999999999999 4497500.0 19746.4 17772.4 20974.1 20924.0 22456.0 21294.3 22283.7 20760.7 23027.0 17754.0 False True 19464.812714953725 17731.249099733 19249.690460367336 22462.82076041781 21135.182230194674 20383.592428437776 23437.440951018518 21725.317912661514 20433.456774940154 20822.755244282023 0.9347856461165872 0.8515323208537467 0.9244545322912223 1.0787631366212285 1.0150041136366161 0.9789094761623901 1.12556867119948 1.0433450164395193 0.9813041807016019 1.0 14.34587335665307 -5.63643753723097 5.367566403541709 1.0342762778235448 0.892172763484899 0.6199745514483288 0.046309413239148285 0.1255611990829239 5.376163144793047 0.01268017057720135 0.022327182356166143 2.3097366348445734e-06 5.63643753723097 -0.14210351433864576 REPEDEGEDDD ddPTM_PC-9_AZD4547_30min_R2 2 REPEDEGEDDD 11 1 P39687 P39687 ANP32A Acidic leucine-rich nuclear phosphoprotein 32 family member A 0 ; 135.71 0.00016773 4261400.0 10828.4 11768.5 13374.1 19807.7 19173.9 13527.3 12035.0 17907.2 13959.199999999999 15739.0 False True 14271.605955288129 15572.437479439332 13196.75069551829 15241.340790914372 16511.934950605424 12681.435792564136 13106.09168511571 15140.053706519275 14697.054813728379 15187.982400578765 0.9396643727177537 1.0253131106371256 0.8688942578057902 1.0035131980620133 1.087171061639906 0.8349651361250515 0.8629251298458366 0.9968443014486464 0.967676576525946 1.0 13.890642611864253 -6.769629501051494 24.99995990894872 0.9279377149107134 0.9817438136707657 0.11367675617328643 0.07237653308490359 446.58436511948156 1363169.5269501924 0.026294146206051583 0.023576840327639285 1.6996930513741963e-07 6.769629501051494 0.05380609876005227 REPEDEGEDDD ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 REPEDEGEDDD 11 1 P39687 P39687 ANP32A Acidic leucine-rich nuclear phosphoprotein 32 family member A 0 125.82 0.00099826 2094100.0 8116.6 10086.0 14274.0 11428.0 17874.0 14685.0 12414.0 13265.0 12641.0 10117.0 False True 9490.580069842672 11087.271423948156 14614.346294446457 10787.726210075887 14371.718009582588 13914.892748534958 11238.05605042309 12916.807805429271 12825.850710577542 11951.13201387206 0.794115574895052 0.9277172581709252 1.2228420100692654 0.9026530873857161 1.2025403110685144 1.16431587672059 0.9403340233693946 1.080802035358351 1.0731912839461708 1.0 13.544859656621648 -5.0149284267996626 5.505858337631865 1.07391989069299 0.8201528018391528 0.4440447140419991 0.10022987572549233 0.12856182454605872 13.54640890927927 0.02455600794700413 0.08119941753159714 9.662101005637034e-06 5.0149284267996626 -0.25376708885383725 REPGYT(ph)PPGAGNQNPPGMYPVTGPK ddPTM_PC-9_AZD4547_30min_R2 3 REPGYTPPGAGNQNPPGMYPVTGPK 25 1 C9JXK9;C9JUT4;A0A087WZF1;Q93052 C9JXK9 LPP Lipoma-preferred partner 1 REPGY(0.008)T(0.992)PPGAGNQNPPGMYPVTGPK;REPGY(0.088)T(0.91)PPGAGNQNPPGMY(0.002)PVTGPK;REPGY(0.001)T(0.999)PPGAGNQNPPGMYPVTGPK 86.191 4.4006e-06 36086000.0 98661.0 98028.0 119279.0 161275.0 133516.0 132378.0 105368.0 137755.0 117695.0 130423.0 True False 130033.14572371545 129713.63395797908 117697.28252448604 124095.54042391176 114979.60805391852 124100.38273329147 114745.54787513701 116468.13004498534 123916.1174208952 125856.93046767174 1.033182243047922 1.0306435527704054 0.9351672735632017 0.9860048227998662 0.9135739098885204 0.9860432975136679 0.9117141777473362 0.9254010058262302 0.9845792119705711 1.0 16.941425136911427 -5.253382294903138 24.49035115711951 0.9517924394665945 1.0319129161867435 0.4870009954515373 0.03128194333328183 344.30055058886006 1046529.6086738638 0.0075439181763240016 0.019178944794861073 5.5797880841517255e-06 5.253382294903138 0.08012047672014899 REPGYT(ph)PPGAGNQNPPGMYPVTGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 REPGYTPPGAGNQNPPGMYPVTGPK 25 1 C9JXK9;C9JUT4;A0A087WZF1;Q93052 C9JXK9 LPP Lipoma-preferred partner 1 REPGY(0.045)T(0.952)PPGAGNQNPPGMY(0.002)PVTGPK;REPGY(0.15)T(0.849)PPGAGNQNPPGMYPVTGPK 66.501 0.00035671 17661300.0 77452.0 71595.0 70841.0 86620.0 91328.0 84381.0 80644.0 77722.0 66924.0 64448.0 True False 90563.09385327053 78702.47844512883 72530.1181059887 81766.96222582896 73432.93400353346 79955.91181573909 73004.81650800051 75681.87985326599 67902.63689223102 76131.91222991268 1.1895549606028122 1.0337646348282077 0.9526900872652874 1.0740169244521123 0.9645486610368001 1.0502286028791477 0.9589252964976295 0.9940887813866066 0.8919076758136606 1.0 16.21621369484558 -4.784578049955611 3.146746530513212 0.9892421200466031 1.2189308194974748 0.6136032652237657 0.04845738994430827 0.22623847194793237 3.383935551392751 0.011901062773737066 0.12981919301417197 1.642184505231905e-05 4.784578049955611 0.22968869945087178 REPPS(ph)PQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 REPPSPQGR 9 1 Q8WXG6-4;Q8WXG6-7;Q8WXG6-2;Q8WXG6;A0A0A0MRB5;Q8WXG6-6;Q8WXG6-8;Q8WXG6-5;Q8WXG6-3 Q8WXG6-4 MADD MAP kinase-activating death domain protein 1 REPPS(1)PQGR;REPPS(1)PQGR 74.53699999999999 0.012508 9221400.0 9926.0 8428.599999999999 11925.3 13099.2 12492.2 13170.7 12648.2 10318.8 8468.0 8055.5 True False 11606.275752563673 9265.33570532316 12209.644378952098 12365.294292179391 10044.44308600804 12480.005306307765 11450.07093096192 10047.942433672333 8591.828480117914 9515.898382697087 1.219672098818074 0.9736690465474569 1.2830784743512071 1.2994353023634013 1.0555433320170815 1.3114899722973463 1.2032569569870324 1.055911068989836 0.9028919955409125 1.0 13.216124150418226 -7.947854325716715 3.5341876104039054 0.9551125928399923 1.1904595733261374 0.47335016847650135 0.10325340036784458 0.2073193418434065 5.229130230499467 0.06825406611176003 0.0279334940151078 1.1275756125433234e-08 7.947854325716715 0.2353469804861451 REPPS(ph)PQGR ddPTM_PC-9_Lapatinib_30min_R1 1 REPPSPQGR 9 1 Q8WXG6-4;Q8WXG6-7;Q8WXG6-2;Q8WXG6;A0A0A0MRB5;Q8WXG6-6;Q8WXG6-8;Q8WXG6-5;Q8WXG6-3 Q8WXG6-4 MADD MAP kinase-activating death domain protein 1 REPPS(1)PQGR 66.538 0.022085 2174500.0 4066.7 3941.7 3229.5 2392.4 3885.1 4313.2 3674.0 2681.5 3585.6 3868.9 True False 4008.708112258558 3932.573235827326 2963.982976230507 2568.345076812445 3656.586056400483 4128.734490560284 3864.2217429799375 2806.092279297031 3181.7519699581094 4537.6342100147995 0.8834357126916768 0.8666571728386409 0.6532000683723778 0.5660097217937865 0.8058353510140159 0.9098870247072688 0.8515939284950284 0.6184042497528418 0.701191815535905 1.0 12.147724599122396 -5.11213709566065 8.63369495036138 0.7525796358127202 0.8792056062835792 0.1048004884284226 0.12804528300391338 0.6253936457031893 43.05909246278589 0.033931429705761455 0.0905593990720416 7.724367080915512e-06 5.11213709566065 0.126625970470859 REQGGSGLGSGSS(ph)GGGGSTSGLGSGYIGR ddPTM_PC-9_Lapatinib_30min_R1 2 REQGGSGLGSGSSGGGGSTSGLGSGYIGR 29 1 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 1 REQGGSGLGS(0.02)GS(0.375)S(0.508)GGGGS(0.062)T(0.027)S(0.006)GLGS(0.001)GY(0.001)IGR;REQGGS(0.001)GLGS(0.001)GS(0.234)S(0.754)GGGGS(0.005)T(0.001)S(0.002)GLGS(0.002)GYIGR 76.029 0.00025073 7985400.0 10006.0 8754.5 10778.0 3253.6 8153.5 7929.799999999999 7463.0 6412.8 10467.5 7037.9 True False 9863.312605124336 8734.229493124874 9891.874444283145 3492.8805976914277 7673.92716039776 7590.660939266657 7849.397623260548 6710.76209907738 9288.53992233839 8254.391637587727 1.1949169651958509 1.058131219913546 1.1983771643737948 0.4231542130598726 0.9296781031630815 0.9195905976524468 0.9509359342143433 0.8129929368166666 1.1252846157724694 1.0 13.010946174691263 -2.551912388677294 9.417491942882751 0.9481153803838125 1.054876236023157 0.0 0.2155760360890558 0.0 0.0 0.04988995051495784 0.0 0.0028059996422538326 2.551912388677294 0.10676085563934445 RES(ph)AASGLGGLLEEEGAGAGAAQEEVLEPGR ddPTM_PC-9_AZD4547_30min_R2 2 RESAASGLGGLLEEEGAGAGAAQEEVLEPGR 31 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RES(0.731)AAS(0.269)GLGGLLEEEGAGAGAAQEEVLEPGR;RES(0.728)AAS(0.272)GLGGLLEEEGAGAGAAQEEVLEPGR 116.35 1.8663e-17 9188900.0 9612.7 5801.5 11629.1 11227.900000000001 14796.9 12480.7 10742.3 19325.2 12753.0 10464.2 True False 12669.338643418982 7676.721420484112 11474.890535681048 8639.481124325763 12742.605848085852 11700.279856013782 11698.343889407435 16338.934388917658 13427.097544234495 10097.8515430546 1.2546568534306761 0.7602331434318061 1.136369502636785 0.8555761676124147 1.2619125755369558 1.158690024915384 1.1584983042708397 1.6180604675413095 1.3296984499113362 1.0 13.301760751942835 -6.736921415023364 1.2561510327187375 1.3255809981401803 0.9972843267741961 0.23056736866095784 0.20311306130998957 0.5368393696507494 1.7834155488465404 0.095664579891032 0.08824651110417167 1.832646007091876e-07 6.736921415023364 -0.32829667136598417 RES(ph)AASGLGGLLEEEGAGAGAAQEEVLEPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RESAASGLGGLLEEEGAGAGAAQEEVLEPGR 31 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RES(0.528)AAS(0.472)GLGGLLEEEGAGAGAAQEEVLEPGR;RES(0.5)AAS(0.5)GLGGLLEEEGAGAGAAQEEVLEPGR;RES(0.5)AAS(0.5)GLGGLLEEEGAGAGAAQEEVLEPGR;RES(0.5)AAS(0.5)GLGGLLEEEGAGAGAAQEEVLEPGR 124.61 1.1029e-16 18028200.0 22583.199999999997 29337.199999999997 27356.8 21443.8 32280.800000000003 18398.0 18479.1 18393.600000000002 16580.2 11894.6 True False 26406.08972146846 32249.603333199673 28009.089863241737 20242.373407737603 25955.608969661742 17433.176492172042 16728.625870901662 17910.787489630147 16822.6540583433 14050.996822398209 1.879303657614912 2.295182593863497 1.993388100308543 1.4406361102772391 1.8472432452825556 1.2407074538926959 1.1905650597141362 1.2746987075734855 1.197256982616841 1.0 13.778384863000438 -6.267434706131091 0.6515291788759566 1.1110101800312635 2.187199445927028 0.7882264846886794 0.18897060510655597 0.38912724592381215 0.35065063462025603 0.12477974131834856 0.2347220538865673 5.402133268643144e-07 6.267434706131091 1.0761892658957644 RES(ph)AASGLGGLLEEEGAGAGAAQEEVLEPGR ddPTM_PC-9_Lapatinib_30min_R1 2 RESAASGLGGLLEEEGAGAGAAQEEVLEPGR 31 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RES(0.721)AAS(0.279)GLGGLLEEEGAGAGAAQEEVLEPGR;RES(0.727)AAS(0.273)GLGGLLEEEGAGAGAAQEEVLEPGR 103.9 1.9515e-15 6518500.0 7727.2 12227.2 10169.800000000001 9640.599999999999 9457.5 12917.4 6194.6 7829.2 9893.6 10353.3 True False 7617.008711005071 12198.888669636928 9333.678300563251 10349.601884098833 8901.228444160408 12364.952913930125 6515.326077589417 8192.973213899799 8779.278583773306 12142.854110094908 0.6272832269863725 1.0046146119383446 0.7686560520235304 0.8523203680339647 0.7330425255426902 1.018290494295783 0.5365563992219037 0.6747156096595616 0.7229995933554609 1.0 13.567819938419113 -7.265056736509008 24.977339292522064 0.7064608841189106 0.8350570598360243 0.08241260302459985 0.15392282693482653 626.04462247205 4322719.282866111 0.05862732745045567 0.041277547868886606 5.4317936555713584e-08 7.265056736509008 0.12859617571711368 RES(ph)ASSSSSVK ddPTM_PC-9_AZD4547_30min_R2 3 RESASSSSSVK 11 1 Q9NPF5 Q9NPF5 DMAP1 DNA methyltransferase 1-associated protein 1 1 RES(0.981)AS(0.004)S(0.005)S(0.005)S(0.002)S(0.002)VK;RES(0.996)AS(0.002)S(0.001)S(0.001)S(0.001)SVK;RES(0.985)AS(0.007)S(0.002)S(0.002)S(0.002)S(0.002)VK 105.03 0.003833 6075100.0 26464.7 25470.199999999997 20779.4 20840.3 16718.600000000002 20611.3 18764.199999999997 20249.0 31515.5 34973.3 True False 34879.92410004373 33702.944053092186 20503.851578981226 16035.89081442534 14397.510974042409 19322.472152704315 20434.177448927967 17119.98232572981 33181.34498983157 33748.895412044054 1.0335130579591072 0.9986384336912114 0.607541412204678 0.47515305667463625 0.42660687996633906 0.572536431690403 0.6054769259688295 0.5072753379543248 0.9831831408025892 1.0 15.042552663649372 -5.252003050342888 6.423326684030912 0.6109770233629925 1.0196975292897 0.36871582217093346 0.18841926855346303 0.1332411421483381 28.063776914057318 0.04730124553046757 0.11638981999371452 5.5975366995396985e-06 5.252003050342888 0.4087205059267074 RES(ph)ASSSSSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RESASSSSSVK 11 1 Q9NPF5 Q9NPF5 DMAP1 DNA methyltransferase 1-associated protein 1 1 RES(0.983)AS(0.006)S(0.002)S(0.002)S(0.003)S(0.003)VK;RES(0.992)AS(0.006)S(0.001)SSSVK;RES(0.936)AS(0.017)S(0.005)S(0.005)S(0.008)S(0.03)VK;RES(0.992)AS(0.006)S(0.001)S(0.001)SSVK 101.53 0.0037650999999999995 5224800.0 7195.5 20879.2 15200.100000000002 13264.8 40303.2 33381.6 19666.3 28231.3 41076.299999999996 47628.3 True False 8413.556032396931 22951.94899017433 15562.528030700261 12521.616261061847 32406.077278941997 31631.010131051735 17803.365692317984 27490.258288534897 41676.96317877511 56262.93376458464 0.14953994520799307 0.4079408494091309 0.2766035645389021 0.2225553383592614 0.5759756043745515 0.5621998003766068 0.3164315207381617 0.488603356582144 0.7407534657392708 1.0 15.779897161801518 -10.846135226197124 0.12645968130172297 1.8261526117657705 2.392622913538241e-09 0.7619809892624313 0.11979025131831297 21.658555494479973 0.4928110396429117 6.983945267523252 1.4104814885708352 1.4251637715142704e-11 10.846135226197124 -1.8261526093731475 RES(ph)ASSSSSVK ddPTM_PC-9_Lapatinib_30min_R1 3 RESASSSSSVK 11 1 Q9NPF5 Q9NPF5 DMAP1 DNA methyltransferase 1-associated protein 1 1 RES(0.985)AS(0.005)S(0.005)S(0.005)SSVK;RES(0.993)AS(0.003)S(0.002)S(0.002)SSVK;RES(0.981)AS(0.011)S(0.003)S(0.003)S(0.001)SVK 126.09 0.00062935 13162400.0 5229.62 11010.1 7720.5 9562.5 20240.0 11909.5 37006.4 37609.9 24985.7 24276.2 True False 5155.0446598051485 10984.60678990853 7085.750291991841 10265.758149564866 19049.52299337103 11400.158447400461 38922.410318294125 39357.39325569024 22171.547354914772 28472.308823996813 0.18105467637596054 0.3857996503834831 0.2488646191565569 0.3605523602958661 0.6690543823167532 0.4003945910347905 1.3670268385642768 1.382304241604718 0.7787056361312125 1.0 14.797271865740765 -7.251090398229642 24.461542898404502 1.1638678615728237 0.3818832089094176 0.7720690896518164 0.20136956844671752 240.79937791067775 569170.3664077788 0.07914962120984814 0.06058411327944238 5.609312062649111e-08 7.251090398229642 -0.7819846526634061 RES(ph)CGSSVLTDFEGK ddPTM_PC-9_AZD4547_30min_R2 2 RESCGSSVLTDFEGK 15 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RES(0.999)CGS(0.001)SVLTDFEGK;RES(0.61)CGS(0.168)S(0.221)VLT(0.001)DFEGK 93.226 0.0049116 154061000.0 72763.0 71125.0 74210.0 59874.0 69924.0 84473.0 77579.0 87226.0 88495.0 73574.0 True False 95900.12043557968 94114.76532481823 73225.92691204736 46070.974344078655 60216.25957609738 79190.88995625683 84483.38070956318 73747.22595407731 93172.66503387682 70998.19665418276 1.350740229398909 1.325593744066929 1.0313772794640885 0.6489034442449384 0.8481378741124662 1.1153929774016509 1.1899369940487912 1.0387197059847095 1.3123243888531595 1.0 16.11549476034834 -5.261741052625488 5.885564298215806 1.0134421535274942 1.3415421363819653 0.351738666028526 0.17091672355283288 0.17271186961369028 26.51601552569768 0.049304297311746764 0.11845190075655498 5.473422175218883e-06 5.261741052625488 0.32809998285447106 RES(ph)CGSSVLTDFEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 RESCGSSVLTDFEGK 15 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RES(0.795)CGS(0.172)S(0.033)VLTDFEGK;RES(0.929)CGS(0.053)S(0.018)VLTDFEGK;RES(0.968)CGS(0.023)S(0.006)VLT(0.003)DFEGK;RES(0.967)CGS(0.028)S(0.005)VLTDFEGK;RES(0.716)CGS(0.234)S(0.05)VLTDFEGK;RES(0.826)CGS(0.134)S(0.04)VLTDFEGK 126.04 1.1335e-05 143687700.0 188468.0 270504.0 213345.0 192697.0 214038.0 150165.0 187539.0 177862.0 148838.0 130964.0 True False 220371.90998732363 297357.8494213436 218431.95391541824 181900.81182210342 172098.79038463935 142290.0830496257 169773.94825521932 173193.31096036636 151014.47417616786 154706.73648954614 1.4244493484109828 1.9220743463969114 1.4119097776338794 1.1757782236870782 1.112419499562441 0.9197407060502537 1.0973920858752735 1.1194943083300668 0.9761337974211112 1.0 17.239176492739368 -5.6851766858259145 2.2992673790013303 1.0469527787036552 1.6774267795147457 0.7858346403175142 0.13155184693374788 0.11904660951940742 1.2758214235252723 0.03659920276466229 0.07370249778986414 2.0645400595342114e-06 5.6851766858259145 0.6304740008110905 RES(ph)CGSSVLTDFEGK ddPTM_PC-9_Lapatinib_30min_R1 2 RESCGSSVLTDFEGK 15 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RES(0.971)CGS(0.018)S(0.011)VLTDFEGK;RES(0.976)CGS(0.023)S(0.001)VLTDFEGK 114.52 0.00025623 84975200.0 27940.7 47400.0 48153.0 45351.0 55525.0 47663.0 45674.0 46245.0 44727.0 45260.0 True False 27542.26049430317 47290.24821224731 44194.04621595528 48686.263826501076 52259.12866635011 45624.5645978797 48038.77623540163 48393.71152567264 39689.37426380982 53083.13069484083 0.5188514719042374 0.8908714989721483 0.8325440801525769 0.9171701666652625 0.9844771395789057 0.8594927239721746 0.9049725516673518 0.9116589562863903 0.7476833740642062 1.0 15.695965838892247 -4.7613902208714345 9.666541699050796 0.8925195229455162 0.5170021123873604 0.7304838707330134 0.06841248150865936 0.03817006391214539 65.44464426852404 0.01642935566932926 0.09336282214836657 1.732246845469406e-05 4.7613902208714345 -0.3755174105581558 RES(ph)CGSSVLTDFEGKDVATK ddPTM_PC-9_AZD4547_30min_R2 7 RESCGSSVLTDFEGKDVATK 20 2 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RES(0.977)CGS(0.019)S(0.004)VLTDFEGKDVATK;RES(0.956)CGS(0.022)S(0.022)VLT(0.001)DFEGKDVATK;RES(0.919)CGS(0.04)S(0.04)VLT(0.001)DFEGKDVATK;RES(0.943)CGS(0.033)S(0.012)VLT(0.012)DFEGKDVATK;RES(0.981)CGS(0.01)S(0.01)VLTDFEGKDVATK;RES(0.98)CGS(0.016)S(0.005)VLTDFEGKDVATK;RES(0.962)CGS(0.031)S(0.006)VLTDFEGKDVATK 126.84 5.7078999999999993e-05 656727500.0 280257.0 235123.6 290599.2 463130.0 394308.0 311272.0 274751.0 332918.0 281718.0 331739.0 True False 369372.89629226655 311122.705607401 286745.6647338557 356362.53378717194 339565.14045151643 291808.1126331949 299203.3067367872 281473.1727945731 296609.03834130435 320124.9185834927 1.1538398757793962 0.9718790620363912 0.8957305354505501 1.113198358203496 1.0607269873087168 0.91154451182496 0.9346454754622644 0.8792604275857435 0.9265415502603085 1.0 18.288275455342863 -6.767165284515679 24.937187525979706 0.9231175953252311 1.031496248565623 0.3552013486308203 0.07252384974734061 162.743537178181 708767.8230670155 0.025914495255556457 0.023467352470160466 1.7093646384454407e-07 6.767165284515679 0.10837865324039186 RES(ph)CGSSVLTDFEGKDVATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 RESCGSSVLTDFEGKDVATK 20 2 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RES(0.944)CGS(0.024)S(0.024)VLT(0.007)DFEGKDVATK;RES(0.929)CGS(0.012)S(0.012)VLT(0.046)DFEGKDVATK;RES(0.485)CGS(0.485)S(0.031)VLTDFEGKDVATK;RES(0.996)CGS(0.002)S(0.002)VLTDFEGKDVATK;RES(0.885)CGS(0.082)S(0.033)VLTDFEGKDVATK;RES(0.744)CGS(0.127)S(0.127)VLT(0.002)DFEGKDVATK;RES(0.952)CGS(0.022)S(0.022)VLT(0.003)DFEGKDVATK;RES(0.988)CGS(0.008)S(0.004)VLTDFEGKDVATK 116.73 4.8941000000000005e-05 620110000.0 309151.0 215083.2 247879.0 351530.0 359616.0 341312.0 320483.0 431344.0 338986.0 263785.0 True False 361484.15828942234 236435.23866065132 253789.3754463425 331834.91377563676 289151.8263250567 323412.9978745633 290124.5301440104 420021.6770467463 343943.0289514948 311607.1323790887 1.1600638134612888 0.7587606768031667 0.8144530374150504 1.0649143722806054 0.9279371242802178 1.0378870194829561 0.9310586953801061 1.3479206134979118 1.1037713621171787 1.0 18.249368730077016 -7.729315438827112 24.994648298222437 1.1693846398114687 0.94958361332992 0.29504621297756906 0.13629285418289203 200.7877209204299 156226.75664429422 0.0627152887854275 0.03620504723756815 1.8650245852719268e-08 7.729315438827112 -0.21980102648154864 RES(ph)CGSSVLTDFEGKDVATK ddPTM_PC-9_Lapatinib_30min_R1 7 RESCGSSVLTDFEGKDVATK 20 2 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RES(0.963)CGS(0.018)S(0.018)VLTDFEGKDVATK;RES(0.973)CGS(0.02)S(0.007)VLTDFEGKDVATK;RES(0.675)CGS(0.03)S(0.147)VLT(0.147)DFEGKDVATK;RES(0.965)CGS(0.029)S(0.006)VLTDFEGKDVATK;RES(0.965)CGS(0.027)S(0.008)VLTDFEGKDVATK;RES(0.76)CGS(0.118)S(0.118)VLT(0.005)DFEGKDVATK;RES(0.898)CGS(0.051)S(0.051)VLTDFEGKDVATK 92.39 0.0017809999999999998 616075000.0 395864.0 238741.0 318763.0 294068.0 267358.0 283366.0 208073.8 177198.1 301576.0 230723.0 True False 390218.90676743275 238188.20988270303 292555.53660076356 315694.7417020909 251632.52808605184 271247.09673840867 218846.8432510777 185431.37061946813 267609.33514393313 270603.16313092754 1.4420337968430577 0.8802122160244631 1.0811238612876624 1.1666335975139597 0.9298949989150828 1.0023796233570617 0.8087371955263942 0.6852520438933294 0.988936463445751 1.0 18.04581917778168 -6.585022311166379 1.323469066425705 0.8529902738572511 1.1260720149499368 0.3422109423570777 0.15908819997928977 0.48975161108579457 1.7877296987855276 0.06879035775135364 0.07277724435757811 2.600025987665425e-07 6.585022311166379 0.2730817410926857 RES(ph)DESGESAPDEGGEGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RESDESGESAPDEGGEGAR 19 1 Q7Z3C6;H7C152;Q7Z3C6-2 Q7Z3C6 ATG9A Autophagy-related protein 9A 1 RES(0.955)DES(0.045)GESAPDEGGEGAR;RES(0.704)DES(0.292)GES(0.004)APDEGGEGAR 106.63 9.980799999999999e-05 1907900.0 6467.4 4987.4 5980.8 6020.5 9049.3 7178.6 5826.9 5838.6 4860.0 2790.2 True False 7562.20308302743 5482.516111421677 6123.404954310305 5683.190903724352 7276.15462594359 6802.141578796944 5274.933848897234 5685.342936508055 4931.068305783315 3296.0411727889523 2.294329071329123 1.6633639642257971 1.8578059657941022 1.724247546008507 2.207543608985581 2.063730767368205 1.600384695569151 1.724900460420338 1.4960578607126078 1.0 11.686518548848097 -8.519801787029616 0.8147061775615891 1.0036716611208358 1.9396046930585562 0.6747488670790971 0.20340955651843373 0.4164547221574574 0.6188185060204668 0.1991476480831423 0.0727441648912797 3.0213303476846032e-09 8.519801787029616 0.9359330319377204 RES(ph)EALDSPNSK ddPTM_PC-9_AZD4547_30min_R2 2 RESEALDSPNSK 12 1 P0C7T5 P0C7T5 ATXN1L Ataxin-1-like 1 RES(1)EALDSPNSK;RES(1)EALDSPNSK 96.70700000000001 0.0061691 9465900.0 43817.0 49538.0 60613.0 63209.0 60445.0 67623.0 57437.0 71399.0 58489.0 62877.0 True False 57749.89454978204 65550.1897316111 59809.23201616935 48637.141619315014 52053.255106647324 63394.523119954836 62548.781729787355 60365.92513579838 61580.60913233992 60675.69536826932 0.951779690356588 1.0803368520748906 0.9857197623061261 0.8015918288882119 0.857893012856493 1.0448091733466534 1.030870455627239 0.9948946570683567 1.0149139413825956 1.0 15.888831116895453 -6.790441171876323 24.999996858528313 1.0176393764917422 0.9388672459893288 0.25104280018329883 0.07037477531058778 372.6314980592138 321211.479418606 0.02837139071565519 0.025025126273382436 1.62016344113191e-07 6.790441171876323 -0.07877213050241338 RES(ph)EALDSPNSK ddPTM_PC-9_Lapatinib_30min_R1 4 RESEALDSPNSK 12 1 P0C7T5 P0C7T5 ATXN1L Ataxin-1-like 1 RES(1)EALDSPNSK;RES(0.997)EALDS(0.002)PNSK;RES(0.992)EALDS(0.008)PNSK;RES(1)EALDSPNSK 95.854 0.0056229999999999995 13216000.0 105933.3 49804.1 68376.0 43905.1 107608.0 122374.0 128549.0 123488.0 141740.0 139948.0 True False 104422.67171621208 49688.78166640478 62754.38921899287 47134.0275171201 101278.70900546799 117140.34928772693 135204.63822491217 129225.70329510755 125775.74861163046 164137.82533101158 0.6361889558706298 0.30272596560968795 0.3823274074238407 0.28716127694555715 0.617034548869052 0.7136706548383572 0.823726267557458 0.7872999598630124 0.7662813148522132 1.0 17.324548218645837 -6.631799490461278 2.0901383488186003 0.8190431500780692 0.3944880765150816 0.7537560046077063 0.11216487699862751 0.15395786362977257 1.374110382991789 0.04125163511916866 0.04139271692748176 2.3345356459109625e-07 6.631799490461278 -0.42455507356298755 RES(ph)GAAEQVDNK ddPTM_PC-9_AZD4547_30min_R2 1 RESGAAEQVDNK 12 1 Q9P2R3;Q9P2R3-2;Q9P2R3-4 Q9P2R3 ANKFY1 Rabankyrin-5 1 RES(1)GAAEQVDNK 91.969 0.012502 0.0 17708.0 18435.0 21195.0 28865.0 27058.0 26158.0 21307.0 24514.0 20792.0 22267.0 True False 23338.775650718664 24393.75323392649 20913.940451433016 22210.620209804445 23301.463755077555 24522.336124865473 23203.281722871656 20725.92457567981 21891.022672290706 21487.439107547314 1.0861590128961007 1.1352564217556458 0.9733100508979285 1.0336559930961302 1.084422561406728 1.1412405174077804 1.0798532857608734 0.964560014431872 1.0187823017309512 1.0 14.391205930858883 -7.7504427645316305 24.97120598426717 0.9937533693585197 1.0757530534444 0.3918668196273367 0.04670542830279887 225.0194063623926 510979.0392402767 0.02398574681391623 0.013680823569065872 1.7764673726730673e-08 7.7504427645316305 0.08199968408588032 RES(ph)GAAEQVDNK ddPTM_PC-9_Lapatinib_30min_R1 1 RESGAAEQVDNK 12 1 Q9P2R3;Q9P2R3-2;Q9P2R3-4 Q9P2R3 ANKFY1 Rabankyrin-5 1 RES(1)GAAEQVDNK 85.271 0.014503 0.0 5503.4 7406.3 6523.9 5224.4 6514.7 5448.8 5641.6 5625.5 5491.6 4322.5 True False 5424.920506800043 7389.151167391717 5987.530124982263 5608.6198040875015 6131.518154393 5215.767525773181 5933.694443439199 5886.881266897423 4873.078178888323 5069.638365630787 1.0700803717239207 1.4575302288790228 1.1810566539763963 1.106315559332732 1.2094586856453398 1.0288243755477835 1.1704374189027391 1.1612033921013123 0.9612279668555792 1.0 12.307667123267636 -6.7763278590746205 0.3178663368148103 0.9885445202096845 1.3012783816787845 0.3064472867424314 0.11122277934593346 2.6559598504934443 0.5622659440871852 0.14321149642475858 0.2997642032577146 1.673678899588543e-07 6.7763278590746205 0.3127338614691 RES(ph)LGLESK ddPTM_PC-9_AZD4547_30min_R2 2 RESLGLESK 9 1 Q96BH1 Q96BH1 RNF25 E3 ubiquitin-protein ligase RNF25 1 RES(1)LGLESK;RES(1)LGLESK 80.17 0.019445 16456700.0 74383.0 59265.0 74437.0 112673.0 108669.0 79703.0 69585.0 123610.0 93125.0 98532.0 True False 98035.2467374863 78421.25225975887 73449.91674372829 86697.98063049692 93582.1851134791 74719.15881031242 75777.9301959932 104508.91477522181 98047.3973815446 95082.4246708068 1.031055393011934 0.8247712711499309 0.7724867871010409 0.9118192024515741 0.9842216943612682 0.785835648060135 0.7969709487147665 1.099140194805205 1.0311831836535836 1.0 16.536891073069036 -7.765719227613621 24.999877507077944 1.0488712924513999 0.8692545137827475 0.46675035333946124 0.08364411796727685 96.68438883447527 564746.5360489496 0.04490242132694135 0.022764188778207194 1.7150657431338607e-08 7.765719227613621 -0.17961677866865233 RES(ph)LGLESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RESLGLESK 9 1 Q96BH1 Q96BH1 RNF25 E3 ubiquitin-protein ligase RNF25 1 RES(0.993)LGLES(0.007)K;RES(1)LGLESK;RES(1)LGLESK 122.34 0.00071606 31850800.0 195644.0 168865.0 136021.0 166259.0 177584.0 130238.0 104929.0 195442.0 109353.0 97095.0 True False 228762.66505486294 185628.80121009413 139264.25650251546 156944.04724895087 142787.68999741046 123408.09000910431 94989.3654998264 190311.85458791623 110952.08074944909 114697.55489640294 1.9944859788989033 1.61841986411792 1.2141867943767557 1.36832949395221 1.2449061370696095 1.07594351179124 0.8281725411289075 1.659249447469125 0.9673447777475567 1.0 16.807475110982935 -3.2941675866291003 0.6675125284505048 1.14098916378482 7.767696075563969 0.6130597373917397 0.21559304930053916 13.220130431862174 0.9278040115090329 0.08800097575458822 103.45493044210212 0.0005079633905666505 3.2941675866291003 6.6267069117791495 RES(ph)LSTSSDLYK ddPTM_PC-9_AZD4547_30min_R2 2 RESLSTSSDLYK 12 1 Q8TB72-4;Q8TB72-3;Q8TB72 Q8TB72-4 PUM2 Pumilio homolog 2 1 RES(0.986)LS(0.005)T(0.002)S(0.002)S(0.005)DLYK;RES(0.746)LS(0.118)T(0.118)S(0.016)S(0.003)DLYK 96.70700000000001 0.0023120999999999997 12318600.0 54799.0 63834.0 62073.0 67145.0 78128.0 70443.0 63104.0 88613.0 79307.0 72285.0 True False 72223.94210999167 84467.09215809396 61249.87146222228 51665.757629908854 67281.27578744538 66038.1880741607 68720.13375135377 74919.89697416648 83499.00611155063 69754.32415184159 1.0354045141742638 1.210922665872664 0.878079921309154 0.7406817893818677 0.9645463074229942 0.9467253661638011 0.9851738166334092 1.0740538007519138 1.1970441564280594 1.0 16.089995033610272 -7.77797062110717 3.3871913396070243 1.1085501762403598 0.9607810797996226 0.1861975530307638 0.11980453305504912 0.41398840941172 9.832327994636042 0.07713386204649424 0.03611314735370207 1.6673600013061714e-08 7.77797062110717 -0.1477690964407372 RES(ph)LSTSSDLYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RESLSTSSDLYK 12 1 Q8TB72-4;Q8TB72-3;Q8TB72 Q8TB72-4 PUM2 Pumilio homolog 2 1 RES(0.421)LS(0.258)T(0.258)S(0.059)S(0.003)DLYK;RES(0.486)LS(0.486)T(0.021)S(0.007)SDLYK 95.073 0.0021593000000000003 10293200.0 104862.0 125578.0 80627.0 81573.0 86070.0 63305.0 47946.0 61190.0 48753.0 43064.0 True False 122613.06548109348 138044.55392391057 82549.45345960025 77002.72927323417 69205.20135866478 59985.17435791665 43404.20778102024 59583.827336164155 49465.92039338559 50871.162305563565 2.4102666407463587 2.713611163329233 1.6227160874319588 1.513681342893412 1.360401418449527 1.1791587146684148 0.8532183227956893 1.1712692345865219 0.9723764536037681 1.0 15.634560436858228 -5.483178624120236 0.8908092146216885 1.0346582101760347 2.8433884889106404 0.9025351530375496 0.18442570451816223 0.2617762627405548 0.31669229239989005 0.07168989114195107 0.37748615407752223 3.2871640292033225e-06 5.483178624120236 1.8087302787346058 up RES(ph)LSTSSDLYK ddPTM_PC-9_Lapatinib_30min_R1 2 RESLSTSSDLYK 12 1 Q8TB72-4;Q8TB72-3;Q8TB72 Q8TB72-4 PUM2 Pumilio homolog 2 1 RES(0.752)LS(0.215)T(0.033)SSDLYK;RES(0.995)LS(0.003)T(0.001)S(0.001)SDLYK 132.31 0.00029905 8559600.0 56075.0 81448.0 90812.0 87257.0 80637.0 73358.0 67712.0 76764.0 75933.0 86205.0 True False 55275.36021710441 81259.41216015026 83345.78790445748 93674.17086081908 75894.09019844169 70220.64934585018 71217.7960426394 80330.73568075954 67380.62593006165 101105.41938905761 0.5467101620379285 0.8037097581036765 0.8243454051037524 0.9264999979907823 0.7506431470938096 0.6945290348446939 0.7043914804268853 0.7945245286174396 0.6664393099521042 1.0 16.625500804181918 -11.156545277359937 3.047270751432583 1.0188175964432358 0.7539418182423635 0.3762279752239198 0.09770078784873346 149338990.07301462 165221459.65979046 22346158.26735702 0.02523190696760012 6.9735629022984915e-12 11.156545277359937 -0.26487577820087227 RES(ph)LSYIPK ddPTM_PC-9_AZD4547_30min_R2 2 RESLSYIPK 9 1 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 RES(0.999)LS(0.001)YIPK;RES(0.948)LS(0.052)YIPK 89.35600000000001 0.013821 5749000.0 87339.0 75030.0 92205.0 110954.0 103752.0 103234.0 69793.0 88089.0 68936.0 77856.0 True False 115110.98523594502 99281.9802083812 90982.30145432327 85375.26952221163 89347.82568988104 96778.76166046184 76004.4417930438 74476.86913384448 72579.8162243667 75130.28513752187 1.5321515820849163 1.3214641742228312 1.210993692993247 1.1363629109877178 1.1892384745556965 1.28814580542738 1.011635210140915 0.9913028946651626 0.9660527188405225 1.0 16.19710695720019 -1.522878745288766 0.2549401333388301 0.9670607302799512 4.395719557785885 0.8006043800181576 0.07714441603380812 24.42504108435219 0.33465481348850434 0.10791715675570843 36.144587022971116 0.029999999999417784 1.522878745288766 3.4286588275059335 RES(ph)LSYIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RESLSYIPK 9 1 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 RES(0.996)LS(0.004)YIPK;RES(0.977)LS(0.023)YIPK;RES(0.963)LS(0.037)YIPK 98.40700000000001 0.0020832 6067300.0 133332.0 185803.0 141850.0 151509.0 152500.0 133399.0 143681.0 119110.0 126444.0 114528.0 True False 155902.47417296222 204248.2939107516 145232.24196912078 143020.4419288056 122618.71973040966 126403.32160448171 130070.49551964243 115983.48870747686 128293.00429145365 135291.01979685063 1.1523490207041176 1.5096958705570065 1.073480281153898 1.0571318195661565 0.9063330287149188 0.934306813521589 0.9614126326710583 0.85728889383519 0.9482743531987192 1.0 17.04570655525518 -5.585386706038065 2.2562385602721045 0.9372024517914667 1.3297922580848647 0.6906551744044451 0.09844079665953653 0.14794982600312098 1.5053878925506141 0.026537148658888017 0.05979954723829329 2.5978453503017893e-06 5.585386706038065 0.392589806293398 RES(ph)LSYIPK ddPTM_PC-9_Lapatinib_30min_R1 2 RESLSYIPK 9 1 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 RES(0.999)LS(0.001)YIPK;RES(0.997)LS(0.003)YIPK 87.568 0.0049464 9168600.0 142420.0 150649.0 149506.0 130886.0 138731.0 138450.0 129154.0 125958.0 147804.0 116539.0 True False 140389.06468337093 150300.18149634733 137214.19378984923 140511.7930628966 130571.11533564032 132528.8162427132 135840.96216462465 131810.46851228594 131156.75707487977 136682.61087154335 1.0271172301157678 1.0996291374445724 1.0038891773790117 1.028015137894549 0.9552869564245687 0.9696099262199932 0.9938423132134219 0.9643543364573542 0.9595716400101775 1.0 17.06047018552158 -5.780294559637802 1.531376118418096 0.9734303535826299 1.060747486220272 0.6107608262480926 0.02596980984420869 0.24108840951088645 1.144901008001843 0.008026634130823477 0.017716697296589458 1.6584616765258618e-06 5.780294559637802 0.08731713263764207 RES(ph)PPAGQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RESPPAGQK 9 1 J3KPC5;P47736-3;F2Z357;P47736;A0A0A0MQY8;X6R8W7;P47736-2;P47736-4 J3KPC5;P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 RES(1)PPAGQK 59.198 0.034476 7864200.0 41516.0 54558.0 48861.0 49957.0 67467.0 56270.0 43636.0 45746.0 46971.0 48797.0 True False 48543.83882162339 59974.157678739226 50026.03154637436 47158.07125277924 54247.32566591183 53319.102142326374 39502.482182718035 44545.215971893515 47657.86201459836 57643.509823160566 0.8421388456488292 1.0404320948312942 0.8678519351067415 0.8180985404506306 0.9410829741688598 0.9249801461760281 0.6852893292567405 0.7727707092879987 0.8267689139818811 1.0 15.814870561181255 -7.199308177563656 24.999923391636983 0.8022703992455633 0.9077827554981345 0.15258253969693558 0.09338060100027361 335.69924240791016 135076.0602640096 0.034756588896520835 0.026922333580906982 6.319632479083763e-08 7.199308177563656 0.10551235625257116 RES(ph)PPAGQK ddPTM_PC-9_Lapatinib_30min_R1 3 RESPPAGQK 9 1 J3KPC5;P47736-3;F2Z357;P47736;A0A0A0MQY8;X6R8W7;P47736-2;P47736-4 J3KPC5;P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 RES(1)PPAGQK;RES(1)PPAGQK;RES(1)PPAGQK 75.566 0.011821 83783000.0 93333.0 123137.0 116699.0 109503.0 133383.0 112892.0 116664.0 124102.0 149321.0 99692.0 True False 92002.05430482398 122851.88384201463 107104.4586911669 117556.21591129953 125537.6741810676 108063.87232410532 122704.29107866388 129868.23197662497 132502.89656016164 116923.62936876006 0.7868559571877719 1.050701936856217 0.916020647574795 1.0054102540774235 1.0736724035920926 0.9242261201393915 1.0494396362917582 1.1107098939517137 1.1332431030024466 1.0 16.83520699137427 -3.0878337139535 0.43831171905080923 1.0626785643125118 1.6911563772576043e-15 0.4625581615011499 0.07274154674415563 20.98847895277992 0.9610739380441896 0.048817701169560704 15.915119904140901 0.0008168950906276602 3.0878337139535 -1.06267856431251 RES(ph)PSEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RESPSEER 8 1 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 RES(1)PSEER 86.189 0.005804800000000001 2027000.0 0.0 787.64 512.88 375.05 2306.6 613.23 958.33 0.0 1130.9 1132.2 True False 0.0 865.8316938685832 525.1090043082312 354.03716442850595 1854.6382880666445 581.0711392702825 867.5500446916344 0.0 1147.437273047397 1337.458897509731 0.0 0.6473706933952964 0.39261692847978574 0.2647088184075803 1.3866880631022536 0.43445906289322417 0.6486554811568124 0.0 0.857923391278683 1.0 10.385278840273036 -4.758336106343936 24.95152406960779 0.5945123891974197 8.108267569132815e-07 0.19758519091567595 0.3735863502318963 148.10821903255552 1190638.095602404 0.09072326497039182 0.626328189057257 1.7444715603507594e-05 4.758336106343936 -0.5945115783706627 RES(ph)PSEER ddPTM_PC-9_Lapatinib_30min_R1 1 RESPSEER 8 1 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 RES(0.997)PS(0.003)EER 55.721000000000004 0.040494 632090.0 463.14 699.75 0.0 559.93 505.02 1030.0 603.64 988.33 623.37 427.24 True False 456.5355386705258 698.1297718675121 0.0 601.1091200717236 475.31571650752187 985.9493010472711 634.8935255667961 1034.2514198760516 553.159506222888 501.08786473848426 0.9110887945945166 1.3932282559504074 0.0 1.1996082171845053 0.9485676065126567 1.967617598486114 1.267030335883597 2.0640121077684115 1.103917187281276 1.0 8.968919789019758 -6.639992504459866 7.97695781977987 1.5325232629195786 0.8783858999581102 0.2856483482376586 0.46381041699298475 0.2863623582163974 18.813133660305887 0.14697591934330687 0.146815689401156 2.290907191466351e-07 6.639992504459866 -0.6541373629614684 RES(ph)PSPAPK ddPTM_PC-9_AZD4547_30min_R2 4 RESPSPAPK 9 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 RES(0.978)PS(0.022)PAPK;RES(0.997)PS(0.003)PAPK;RES(0.996)PS(0.004)PAPK;RES(1)PSPAPK 112.94 0.0031359 126386000.0 261153.0 341796.0 312022.0 272030.0 279713.0 363330.0 321386.0 341204.0 374455.0 320230.0 True False 344194.22168015223 452274.8728149255 307884.3844084466 209317.686321604 240879.6781478314 340610.91766371106 349988.7313928212 288478.76188791136 394247.926834966 309018.8451704263 1.1138292277622306 1.4635834671037373 0.9963288298441668 0.6773622049042468 0.7794983442352339 1.10223348183138 1.1325805427814595 0.9335312923353043 1.2758054500447544 1.0 18.237335296401064 -5.3442561259346535 8.233452518662986 0.9748226832864749 1.2877928525533509 0.3095634742692509 0.17948238469613406 0.35104260750959043 31.731581019160423 0.04945409261797709 0.10341446853504022 4.526305615042221e-06 5.3442561259346535 0.31297016926687593 RES(ph)PSPAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RESPSPAPK 9 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 RES(0.991)PS(0.009)PAPK;RES(0.991)PS(0.009)PAPK;RES(0.979)PS(0.021)PAPK;RES(0.999)PS(0.001)PAPK 92.943 0.0030432 88107600.0 342923.0 641958.0 427541.0 376324.0 443173.0 282257.0 374340.0 261425.0 285928.0 275745.0 True False 400973.0908620187 705687.3476873809 437735.19889827154 355239.7863388693 356336.43199400004 267454.9460349493 338879.805213097 254562.8707526831 290109.1560773681 325735.3857037812 1.2309779915242538 2.1664436185300486 1.3438368016189106 1.0905778184686357 1.0939444949283066 0.8210804161085794 1.0403530598338773 0.7815020471376687 0.8906283100024907 1.0 18.313340927380196 -5.662777322967214 2.5610691228143643 0.9409869866381741 1.709728765163128 0.6157845622130821 0.23436363118797626 0.16027225344252685 2.120836170070297 0.0638736608274717 0.1263797435014988 2.173815479702934e-06 5.662777322967214 0.768741778524954 RES(ph)PSPAPK ddPTM_PC-9_Lapatinib_30min_R1 3 RESPSPAPK 9 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 RES(0.989)PS(0.011)PAPK;RES(0.998)PS(0.002)PAPK;RES(0.922)PS(0.078)PAPK 130.01 0.0018798999999999999 61699000.0 71891.0 211861.0 184390.0 199656.0 244541.0 221130.0 259890.0 283286.0 208538.0 204680.0 True False 70865.82115680524 211370.44887120093 169230.1659659832 214339.3682728916 230157.57916610382 211672.78537920702 273345.8325484637 296448.5017463877 185050.25443750698 240058.66528104348 0.29520209601199193 0.8804949766080868 0.7049533736591456 0.8928624510261207 0.9587555562580998 0.8817544042053042 1.1386626357705105 1.2349002332381005 0.7708543002222537 1.0 17.873027487635397 -4.6468115921561655 0.669853449588391 1.0228456429642134 1.6205130896182586e-15 0.6086826409267183 0.15297334709601462 2.6762111766904297 0.8019415472203555 0.06752335329471942 2.1788747011923695 2.2552173698467563e-05 4.6468115921561655 -1.0228456429642119 RES(ph)PSPAPKPR ddPTM_PC-9_AZD4547_30min_R2 1 RESPSPAPKPR 11 2 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 RES(0.973)PS(0.027)PAPKPR 45.115 0.044773 258190000.0 19530.0 17849.0 21392.0 28068.0 26825.0 21390.0 18836.0 24601.0 20204.0 21418.0 True False 25740.13375076439 23618.340193781074 21108.32810271551 21597.35624627719 23100.8117832048 20052.479918605113 20512.367509832944 20799.48072474094 21271.942192716502 20668.16233913182 1.2454002116109575 1.1427402110667366 1.021296802123056 1.0449577418591343 1.1177003259485316 0.9702110709977823 0.9924620860460388 1.0063536556107116 1.029213040021537 1.0 14.335122500190906 -1.5228787665800079 0.6117703110795868 1.0104449265445523 17.543676755399552 0.7849909618245572 0.037737101014000914 83.52871846213161 0.6207708373965407 0.017578685991184003 1852.3044731989937 0.029999998528670937 1.5228787665800079 16.533231828855 RES(ph)PSPAPKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RESPSPAPKPR 11 2 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 RES(0.977)PS(0.023)PAPKPR 45.28 0.044481 130490000.0 10402.0 11221.0 13410.0 13814.0 15381.0 13080.0 12371.0 13014.0 11847.0 9447.7 True False 12162.85315113514 12334.946722994478 13729.745257708202 13040.046365592269 12367.203463432359 12394.061773975984 11199.129321716126 12672.396289472783 12020.23996267797 11160.493222047953 1.0898132286041793 1.105233118069222 1.2302095422256607 1.1684112974354208 1.1081233792607397 1.1105299315527626 1.0034618631004448 1.1354691981209228 1.0770348338128601 1.0 13.446113165970942 -6.7512062124211925 2.177095062833423 1.0656889825983864 1.1492901873857095 0.37163031255630574 0.05196115028752561 0.37358012184001815 3.639684761189227 0.02097942432767574 0.0194589414042948 1.7733472572875327e-07 6.7512062124211925 0.08360120478732314 RES(ph)PSPAPKPR ddPTM_PC-9_Lapatinib_30min_R1 2 RESPSPAPKPR 11 2 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 RES(0.997)PS(0.003)PAPKPR;RES(0.992)PS(0.008)PAPKPR 83.243 0.031787 628320000.0 46232.0 40040.0 45384.0 40568.0 44371.0 40515.0 31481.0 35030.0 36537.0 35468.0 True False 45572.723202089575 39947.28984005028 41652.7027073062 43551.5060508808 41761.185016742405 38782.26789507789 33110.932142283986 36657.62168330222 32421.8183083332 41598.59654186068 1.0955351139365899 0.9603037881302393 1.0013006728578229 1.0469465239543576 1.0039085086612984 0.9322975080674004 0.7959627221789669 0.8812225587085286 0.7793969269061064 1.0 15.344247234928963 -6.9286621217291415 3.0600414661139004 0.8543230272227047 1.0191620220546627 0.5657615393431645 0.06476643120173708 0.1739182848492003 3.2978788206588177 0.0234796756221528 0.019916021638989794 1.1785224997576004e-07 6.9286621217291415 0.16483899483195796 RES(ph)QEEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RESQEEPR 8 1 A0A3B3ISQ4;Q9H6S3;Q9H6S3-3;H0YD62;H0YF37 A0A3B3ISQ4 EPS8L2 Epidermal growth factor receptor kinase substrate 8-like protein 2 1 RES(1)QEEPR;RES(1)QEEPR 68.626 0.01975 2966100.0 9552.0 13062.400000000001 7960.900000000001 9494.8 11324.099999999999 11069.2 8284.3 10197.5 10978.4 10105.5 True False 11168.964939400392 14359.148745605831 8150.718047881378 8962.837138556926 9105.223895732028 10488.711665787074 7499.551130861931 9929.826430144365 11138.938330907718 11937.547154906013 0.9356164038112508 1.2028558764439816 0.682779966614134 0.7508106164735391 0.7627382558225141 0.8786320614847996 0.6282321680949186 0.8318146350578789 0.9331010957581778 1.0 13.543218811547234 -5.264170729969466 24.997997398236155 0.794876932603838 1.0692361423871768 0.4192785605364757 0.12189346033425703 188.67853733119202 1726850.7351160583 0.030300290272630318 0.06786572445203776 5.442886398748237e-06 5.264170729969466 0.27435920978333883 RES(ph)QYQENR ddPTM_PC-9_AZD4547_30min_R2 1 RESQYQENR 9 1 E9PD99;Q96II8-3;Q96II8-4;Q96II8;Q96II8-2 E9PD99 LRCH3 Leucine-rich repeat and calponin homology domain-containing protein 3 1 RES(1)QYQENR 64.439 0.024676 1731100.0 3320.4 1590.4 3774.0 6404.1 8117.3 5267.0 6001.0 7137.2 6502.0 6080.1 True False 4376.218131389561 2104.46569803291 3723.954294112208 4927.733687358689 6990.353009797135 4937.65365737696 6535.077374522589 6034.309736540016 6845.682445903913 5867.237549638407 0.7458736917272532 0.35868084089463986 0.6347031737860541 0.839872878108094 1.1914215081044308 0.8415636175633052 1.1138252574970893 1.02847544274254 1.166764152292727 1.0 12.518465688934436 -5.87874711618477 2.6647332792691523 1.0501709506121353 0.5454183043738244 0.7326464987031072 0.12894351560965406 0.12716603408264876 1.827810162899972 0.03651706906074537 0.06000969749077154 1.3220652308422378e-06 5.87874711618477 -0.5047526462383108 RES(ph)VNLGK ddPTM_PC-9_AZD4547_30min_R2 1 RESVNLGK 8 1 P46013 P46013 MKI67 Antigen KI-67 1 RES(1)VNLGK 73.95100000000001 0.013088999999999998 27500000.0 41619.0 45943.0 52140.0 71462.0 68518.0 58430.0 52469.0 56368.0 48521.0 58288.0 True False 54852.976271022155 60793.176285667774 51448.58953232919 54987.539976893946 59005.458406770704 54776.36286321166 57138.639354078565 47657.62080778003 51085.72100241523 56247.35486148642 0.975209881533131 1.0808184035565014 0.9146846044409631 0.9776022376928681 1.0490352577837008 0.9738478013428864 1.0158458027899624 0.8472864355157804 0.908233304983281 1.0 15.779497632004547 -7.743106534444402 24.999948632381994 0.9083198830973054 0.9983507920616829 0.2998661122605135 0.055111410985522 246.94047297349996 336746.13924428076 0.025164072492108086 0.01449295599168557 1.8067308722105472e-08 7.743106534444402 0.09003090896437749 RES(ph)VNLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RESVNLGK 8 1 P46013 P46013 MKI67 Antigen KI-67 1 RES(1)VNLGK;RES(1)VNLGK 70.808 0.01702 16789800.0 74546.0 84782.0 98137.0 93424.0 107605.0 95074.0 72945.0 79493.0 72427.0 52293.0 True False 87165.16544938649 93198.59665528186 100476.95826664506 88189.75616469473 86520.57269895566 90088.15207178841 66035.12152393346 77406.39297979565 73486.10785657764 61773.306948839774 1.4110490397021496 1.5087195628440013 1.626543295631872 1.4276353415518594 1.4006142292270576 1.4583669957381236 1.0689912000117345 1.2530718655535649 1.1896094200920524 1.0 15.914695944998536 -7.249913053264734 23.13180709730282 1.1490074541525086 1.4755590501788436 0.7850781096722508 0.08794892189963373 130.62688104584382 262151.2409494704 0.03475572479185864 0.026637094881703252 5.6245391846291715e-08 7.249913053264734 0.326551596026335 RES(ph)VNLGK ddPTM_PC-9_Lapatinib_30min_R1 2 RESVNLGK 8 1 P46013 P46013 MKI67 Antigen KI-67 1 RES(1)VNLGK;RES(1)VNLGK 82.494 0.0075132 45578000.0 172073.0 164456.0 175474.0 162652.0 128191.0 121506.0 128582.0 130777.0 138186.0 106749.0 True False 169619.20746567653 164075.21223614638 161047.20506922808 174613.9706711665 120651.05741320278 116309.47162432004 135239.3468034419 136853.37684491088 122622.03751690975 125200.42241589872 1.3547814311857884 1.3105004685296582 1.286315189370937 1.3946755713900285 0.9636633414256098 0.9289862556370285 1.0801828316057533 1.093074401860264 0.9794059408967174 1.0 16.93387990424963 -6.263107384339505 24.999991550266458 1.011909082859148 1.3311166956003302 0.9004933107302873 0.05355671376173763 47.8459649691058 717112.6183393305 0.017550276344709154 0.020942013348350767 5.456229328225626e-07 6.263107384339505 0.31920761274118226 RES(ph)WISDIR ddPTM_PC-9_AZD4547_30min_R2 2 RESWISDIR 9 1 I3L359;I3L2Y6;I3L1M1;I3NI06;I3L1G9;I3L167;A0A0A6YYL4;P57737-2;P57737-4;P57737;P57737-3 I3L359 CORO7;CORO7-PAM16 Coronin;Coronin-7 1 RES(0.949)WIS(0.051)DIR;RES(0.989)WIS(0.011)DIR 65.234 0.023694999999999997 5464100.0 17991.5 17319.2 23668.3 30080.0 28163.0 24626.4 24089.5 27779.0 22033.7 26981.0 True False 23712.42275355235 22917.292704584743 23354.44287740751 23145.520731367305 24253.05357876594 23086.507314985363 26233.418832454903 23486.393847915864 23198.356399309934 26036.403402377233 0.9107411030275905 0.8802019368962573 0.8969918969405409 0.8889676647602572 0.9315055233992701 0.8867010914755403 1.0075669218606316 0.902059838486427 0.890996964549713 1.0 14.668242551865562 -6.7324530711295605 1.5443566034934726 0.9397053982857572 0.8945051346729588 0.2346057509177547 0.03876402035088819 0.6378515243588144 3.161823729970088 0.01675745229735436 0.015575269036723266 1.8515989629532626e-07 6.7324530711295605 -0.045200263612798386 RES(ph)WISDIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RESWISDIR 9 1 I3L359;I3L2Y6;I3L1M1;I3NI06;I3L1G9;I3L167;A0A0A6YYL4;P57737-2;P57737-4;P57737;P57737-3 I3L359 CORO7;CORO7-PAM16 Coronin;Coronin-7 1 RES(0.999)WIS(0.001)DIR;RES(0.985)WIS(0.015)DIR 85.973 0.014213 0.0 17660.7 23543.0 22090.0 23262.5 25789.0 22920.0 21290.0 19464.6 19856.0 14893.2 True False 20650.307695275173 25880.193449733448 22616.709376791514 21959.17754304257 20735.830577885492 21718.034851645996 19273.257073747987 18953.674874448443 20146.356436138572 17593.21926549366 1.1737651525651995 1.4710322800610682 1.2855355825156254 1.2481614201280407 1.1786262801007417 1.234454850127544 1.0954934843306057 1.0773284063834243 1.1451205224078853 1.0 14.102731875628884 -6.88963997959934 0.4901516923697078 1.0301228021439448 1.3495276384246921 0.5987779131612702 0.07850065819657774 0.6900139940013991 0.3549164001091684 0.07139980542878799 0.08710111001258442 1.289317924492041e-07 6.88963997959934 0.31940483628074734 RES(ph)WISDIR ddPTM_PC-9_Lapatinib_30min_R1 1 RESWISDIR 9 1 I3L359;I3L2Y6;I3L1M1;I3NI06;I3L1G9;I3L167;A0A0A6YYL4;P57737-2;P57737-4;P57737;P57737-3 I3L359 CORO7;CORO7-PAM16 Coronin;Coronin-7 1 RES(0.981)WIS(0.019)DIR 82.774 0.0070068 2527000.0 15926.0 15211.0 15934.0 13466.0 14087.0 13627.0 13813.0 10865.0 14051.0 10919.0 True False 15698.8923195293 15175.779864061047 14623.968027018713 14456.334561259147 13258.430356107603 13044.204976088517 14528.169552471922 11369.827564632573 12468.428416410481 12806.334601347047 1.2258692911145703 1.1850213458005983 1.141932370366184 1.1288424839171813 1.0353025099557371 1.018574430713098 1.1344518165989323 0.8878284004414991 0.9736141374206306 1.0 13.644569989565136 -5.836822420770711 0.4610934466424573 0.9633549441205967 1.2821183465114856 0.7058084903164903 0.05462916848371995 1.1254082854563356 0.366128044212505 0.04589076366519157 0.1786666007284197 1.4560543268046189e-06 5.836822420770711 0.31876340239088885 RESAAS(ph)GLGGLLEEEGAGAGAAQEEVLEPGR ddPTM_PC-9_AZD4547_30min_R2 1 RESAASGLGGLLEEEGAGAGAAQEEVLEPGR 31 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RES(0.412)AAS(0.588)GLGGLLEEEGAGAGAAQEEVLEPGR 85.291 3.5741999999999995e-09 6977000.0 5480.7 3393.9 7562.2 3225.9 8004.1 8451.0 7120.1 9218.8 8823.6 5544.3 True False 7223.44859435813 4490.911803668195 7461.920286946299 2482.2185946581726 6892.868875822904 7922.557634040754 7753.775106538623 7794.2462869493775 9289.99748226358 5350.19574455358 1.3501279091912655 0.8393920555598132 1.3947004265297065 0.4639491175972457 1.2883395682933174 1.4807977151314138 1.4492507333833256 1.456815163236561 1.7363845970907998 1.0 12.385375960200296 -6.512757429773125 24.413038161910894 1.4469416287088006 1.0081806016911359 0.3013594824192224 0.29593683825098177 408.02121593409595 984167.4200496449 0.08945821859248686 0.094896659011147 3.0707366344037466e-07 6.512757429773125 -0.43876102701766473 RESAAS(ph)GLGGLLEEEGAGAGAAQEEVLEPGR ddPTM_PC-9_Lapatinib_30min_R1 1 RESAASGLGGLLEEEGAGAGAAQEEVLEPGR 31 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RES(0.421)AAS(0.579)GLGGLLEEEGAGAGAAQEEVLEPGR 81.803 1.7899999999999997e-07 4270200.0 1410.9 3992.0 3510.9 1367.6 4128.5 3505.4 2696.6 4142.8 4136.2 3096.9 True False 1390.780307272629 3982.756769267748 3222.2473544659197 1468.1778661798598 3885.6697469432943 3355.4822134865085 2836.2167534348637 4335.289612034959 3670.33759988307 3632.1950386401363 0.3829035314671113 1.0965151174147463 0.88713500243982 0.4042122877656739 1.0697855444453381 0.9238166391920334 0.7808547512626745 1.1935729127745451 1.0105012425921969 1.0 11.826625958029924 -6.963739807426894 0.8541512860206948 1.0531234002318381 0.7453228341868973 0.2250376832592086 0.23252405288233502 1.0218092788655102 1.5641035316343581 0.1635639536832096 0.12530974013841936 1.087076713110825e-07 6.963739807426894 -0.3078005660449409 RESCGS(ph)SVLTDFEGK ddPTM_PC-9_AZD4547_30min_R2 1 RESCGSSVLTDFEGK 15 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-9;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RES(0.331)CGS(0.506)S(0.163)VLTDFEGK 78.69 0.033174 0.0 19375.0 22268.0 18787.0 29950.0 25914.0 23847.0 24432.0 25712.0 23139.0 27285.0 True False 25535.846974964683 29465.695525526196 18537.872104792263 23045.490222887343 22316.288408200136 22355.843320195247 26606.400668944487 21738.801202981136 24362.08030079525 26329.76045490765 0.9698472957510333 1.1191023015947734 0.7040653535963696 0.8752639532119957 0.8475689874360617 0.849071276530672 1.010506750128267 0.825636117738747 0.9252678292503933 1.0 14.68440677552177 -5.238684073023918 24.998315521192644 0.8757209790835656 1.044474798876826 0.34940249467794027 0.08982373119748033 828.744641608421 910431.6118080443 0.021877849773984 0.05779712924044726 5.771861840766843e-06 5.238684073023918 0.16875381979326032 RESGEEFR ddPTM_PC-9_AZD4547_30min_R2 2 RESGEEFR 8 1 P30533;D6REW6;A0A3B3IRQ7 P30533 LRPAP1 Alpha-2-macroglobulin receptor-associated protein 0 ; 137.13 0.0020778000000000003 10461000.0 13645.3 10712.5 13429.8 22929.0 15131.5 14154.900000000001 15447.9 19350.699999999997 11119.9 16072.0 False True 17984.22156012827 14175.106130644848 13251.712077124566 17643.073299518655 13030.75241370227 13269.79186535127 16822.733173452343 16360.493949849377 11707.675212274215 15509.324171936063 1.159574805501229 0.9139731669478244 0.8544351726881421 1.1375784724033033 0.8401882808846862 0.8556009093782951 1.084685121476336 1.0548811649351875 0.7548797795753804 1.0 13.920848200995056 -4.7558937303139786 24.860998194045898 0.9473760992742778 1.1595751684151774 0.23462513623281056 0.11665241326503345 256.7556762108771 1150898.587804452 0.028565764923228206 0.24278374796796198 1.7543097201338044e-05 4.7558937303139786 0.2121990691408996 RESGEEFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RESGEEFR 8 1 P30533;D6REW6;A0A3B3IRQ7 P30533 LRPAP1 Alpha-2-macroglobulin receptor-associated protein 0 119.21 0.0021953000000000003 3094700.0 5694.8 7128.4 8723.5 7706.5 8855.3 8860.7 9521.7 8777.9 8351.1 6418.6 False True 6658.817162573006 7836.06044204561 8931.50132405798 7274.729789810102 7120.167533302941 8396.029293629126 8619.73564486173 8547.489425953832 8473.219038770987 7582.241370390357 0.8782122379507142 1.0334754671153639 1.1779500134269874 0.9594431823575115 0.9390584110271305 1.1073281479031671 1.1368321349572073 1.1273037890000304 1.117508481312665 1.0 12.888408668145388 -6.792591480140681 23.566066893256952 1.1081910155800123 1.007515950818763 0.2658758761383381 0.08149663390481364 155.4174567693565 117569.12275979044 0.029764418683861205 0.02625351315293301 1.6121614045885216e-07 6.792591480140681 -0.10067506476124932 RESGEEFR ddPTM_PC-9_Lapatinib_30min_R1 1 RESGEEFR 8 1 P30533;D6REW6;A0A3B3IRQ7 P30533 LRPAP1 Alpha-2-macroglobulin receptor-associated protein 0 113.18 0.0023526999999999997 4672300.0 10959.0 9862.3 10834.0 9356.0 7844.2 9136.4 10203.0 7035.5 11950.0 4963.5 False True 10802.722650365527 9839.464450287905 9943.270340449402 10044.071450701069 7382.819578290566 8745.657469988637 10731.261416337582 7362.395014355491 10604.065160921304 5821.4343615519765 1.8556805727661858 1.690213071072871 1.708044739990602 1.725360250909597 1.268213144693489 1.5023200343458087 1.843405035572137 1.2647046341329355 1.82155539379719 1.0 12.507158951771688 -12.43515336629987 0.18630842735994016 2.445419006602063e-26 1.7587303802579046 0.45007306561715954 0.2085656253530016 53.060968666281696 1.0412353218661494 22.56123922651188 0.6410246917211342 3.671526217086489e-13 12.43515336629987 1.7587303802579046 RESGSGPST(ph)DTLSAASLPWPPGSSQLGR ddPTM_PC-9_AZD4547_30min_R2 1 RESGSGPSTDTLSAASLPWPPGSSQLGR 28 1 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;J3QR75 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 RES(0.036)GS(0.051)GPS(0.197)T(0.515)DT(0.197)LS(0.003)AASLPWPPGSSQLGR 86.99700000000001 3.1172e-07 3478400.0 5476.3 4623.5 6649.7 7623.7 10906.0 7379.1 7179.0 9119.4 5173.7 7778.9 True False 7217.64948588382 6117.955957529656 6561.520633163202 5866.173749990858 9391.890151263051 6917.683710489904 7817.917092434208 7710.206272964616 5447.1712196821145 7506.563078712885 0.961511867708357 0.8150142606379954 0.8741045088624333 0.7814726511292706 1.2511571611109986 0.9215513994822844 1.0414775724198284 1.027128686206504 0.7256544922841194 1.0 12.873936797695144 RESGSGPST(ph)DTLSAASLPWPPGSSQLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RESGSGPSTDTLSAASLPWPPGSSQLGR 28 1 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;J3QR75 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 RES(0.047)GS(0.184)GPS(0.184)T(0.537)DT(0.047)LSAASLPWPPGSSQLGR;RES(0.002)GS(0.016)GPS(0.215)T(0.552)DT(0.215)LS(0.001)AASLPWPPGSSQLGR 81.94 6.0249e-06 10162100.0 16301.3 11822.400000000001 16713.3 15788.8 24004.3 16583.1 11617.5 15914.3 14321.4 10084.8 True False 19060.788124649032 12996.049740480345 17111.808457543208 14904.204723980249 19300.829731309346 15713.453043120884 10517.006296583708 15496.566487594657 14530.82338157308 11913.09440876713 1.5999863235048102 1.0909046209619762 1.4363865399194873 1.251077529698068 1.6201357152937028 1.3190068427189647 0.8828106229766794 1.3008011147960319 1.219735434219299 1.0 13.540260579345638 -7.019143571024944 24.550573706592168 1.1223328284094836 1.3856491708756997 0.3807684600005403 0.17948730208818306 716.1352670328105 918402.2263871075 0.06576983224470356 0.05181195467414452 9.568776900678843e-08 7.019143571024944 0.26331634246621616 RESGSGPST(ph)DTLSAASLPWPPGSSQLGR ddPTM_PC-9_Lapatinib_30min_R1 2 RESGSGPSTDTLSAASLPWPPGSSQLGR 28 1 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;J3QR75 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 RES(0.034)GS(0.088)GPS(0.235)T(0.628)DT(0.015)LSAASLPWPPGSSQLGR;RES(0.028)GS(0.125)GPS(0.196)T(0.56)DT(0.07)LS(0.021)AASLPWPPGSSQLGR 99.72200000000001 8.0933e-10 7054100.0 25222.3 22811.0 26835.3 20291.6 21610.4 22252.7 17944.4 19217.9 24734.0 19473.6 True False 24862.625376796655 22758.182531003673 24629.005221253617 21783.911954793257 20339.31875968111 21301.003894577305 18873.473229376476 20110.833792393216 21948.19645943326 22839.585813059046 1.0885760179845683 0.9964358687271453 1.07834727927384 0.9537787652146396 0.8905292296523017 0.9326352968449182 0.8263491896856179 0.8805253281298295 0.9609717373632882 1.0 14.47924886777806 -5.926336066243479 4.080294528136326 0.9064692606015555 1.0480805250479979 0.6018176289024451 0.05018557799022563 0.14088436224008521 4.595908682705866 0.014203052967803387 0.021553464910893803 1.1848515301905267e-06 5.926336066243479 0.14161126444644234 RESIS(ph)PQPADSACSSPAPSTGK ddPTM_PC-9_Lapatinib_30min_R1 1 RESISPQPADSACSSPAPSTGK 22 1 Q9GZR1-2;Q9GZR1;H0Y4F4;F8W6D9 Q9GZR1-2 SENP6 Sentrin-specific protease 6 1 RES(0.078)IS(0.922)PQPADSACSSPAPSTGK 103.64 0.00096054 0.0 9497.7 11756.0 12042.0 11954.0 11871.0 11407.0 9671.6 10547.0 10652.0 10460.0 True False 9362.261056335134 11728.779704286486 11051.953243464242 12833.137037374998 11172.771119283976 10919.149201015747 10172.34812449776 11037.052123716494 9452.259589467256 12267.997062926099 0.7631450356821405 0.9560468301488979 0.9008767435120487 1.0460661974037109 0.9107249587667495 0.8900515010729362 0.829177580685816 0.8996621100497716 0.7704810769829734 1.0 13.582612105872297 -6.862125827473251 3.542085582541333 0.8659828834917084 0.9242772828440016 0.039217664997503565 0.08494264293920352 0.6139666620585829 14.965587372740032 0.03062502592978776 0.027033723156865006 1.373643933606101e-07 6.862125827473251 0.05829439935229319 RET(ph)DDEGEDD ddPTM_PC-9_AZD4547_30min_R2 1 RETDDEGEDD 10 1 Q92688 Q92688 ANP32B Acidic leucine-rich nuclear phosphoprotein 32 family member B 1 RET(1)DDEGEDD 85.92399999999999 0.039533 1851500.0 6915.4 5038.7 4942.7 7249.8 6884.0 5027.8 4507.6 5551.1 7032.6 11519.0 True False 9114.353350744288 6667.361237851124 4877.156568497193 5578.470618293439 5928.275426489538 4713.410871190408 4908.767667621736 4693.3050465879205 7404.328878662549 11115.723316110725 0.8199514409947822 0.5998135297401379 0.4387619617545193 0.5018540368136194 0.5333234066646217 0.4240309638113214 0.4416057802110949 0.4222221904161302 0.6661130965657434 1.0 13.440314209211103 -8.597969443429875 4.608617959169315 0.9999233208870284 0.5169533969303818 0.6193212387277192 0.11346010183835048 0.2804851947706547 15.324386529655968 0.11467912661784246 0.029891321788677202 2.523658328570088e-09 8.597969443429875 -0.4829699239566466 RET(ph)DDEGEDD ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RETDDEGEDD 10 1 Q92688 Q92688 ANP32B Acidic leucine-rich nuclear phosphoprotein 32 family member B 1 RET(1)DDEGEDD 86.11399999999999 0.039117 2109800.0 3443.4 4411.5 4663.0 3423.0 10397.0 8253.0 4577.5 7313.1 8014.3 7884.7 True False 4026.299609749925 4849.4445654121855 4774.183604525975 3231.2204075157338 8359.782485488991 7820.198151423834 4143.886061769908 7121.138873869942 8131.493975933989 9314.133694749142 0.4322784857618866 0.520654386585203 0.512574090193426 0.3469158285045167 0.8975373082954384 0.8396055293722575 0.44490300414154793 0.7645519279892338 0.8730274057068916 1.0 13.185205875363089 -5.971004246926589 0.14522041457828638 1.1496072195444258 2.911300750905635e-10 0.5252709118664765 0.15372526916278456 14.79721458506121 0.6001229467130689 1.1439115655735346 3.7651760134786936 1.0690444250824787e-06 5.971004246926589 -1.1496072192532958 REVQSES(ph)AQEPGAR ddPTM_PC-9_Lapatinib_30min_R1 1 REVQSESAQEPGAR 14 1 A8MTF4;Q96CA5-2 A8MTF4 BIRC7 1 REVQS(0.096)ES(0.904)AQEPGAR 80.37100000000001 0.017153 2624000.0 2403.9 7146.7 11456.0 8341.4 12029.0 20012.0 16248.0 13349.0 22450.0 13206.0 True False 2369.6199451787297 7130.152255241935 10514.13190143883 8954.854382094685 11321.477869923921 19156.13341025049 17089.241937925417 13969.243272920403 19921.44459101952 15488.639504111105 0.1529908385142393 0.4603472276147559 0.6788286278241608 0.5781562918885047 0.7309536687789069 1.2367860589153705 1.1033404149789572 0.9019025376123311 1.2861971889610981 1.0 13.918922805350707 -5.55311998759132 0.5609534606954013 1.1314864101999451 0.016632055946144093 0.8072198502089837 0.1502189014172326 0.8375342656333057 0.361925215385664 0.09972724680827195 0.5510267340100233 2.798208119302957e-06 5.55311998759132 -1.114854354253801 down REVS(ph)PAPAVAGQSK ddPTM_PC-9_AZD4547_30min_R2 2 REVSPAPAVAGQSK 14 1 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 REVS(1)PAPAVAGQSK;REVS(1)PAPAVAGQSK 142.4 0.00021939 8395600.0 37622.0 35032.0 48611.0 59634.0 45460.0 39222.0 35501.0 51795.0 35287.0 37511.0 True False 49585.0134137869 46355.408911902 47966.38637813683 45886.30263611562 39148.6636967191 36769.44213966947 38660.520225450186 43791.27288069416 37152.198780161714 36197.7513074598 1.3698368440795434 1.2806157078146692 1.3251206123473114 1.267656165886171 1.0815219808599315 1.0157935454982765 1.0680365168839325 1.209778820477985 1.026367590201804 1.0 15.143612455909249 -6.193936723069968 3.3636954347429553 1.0733815964777795 1.318030760110814 0.8102892491989325 0.05820550690618344 0.11208011735672128 2.5045833450412136 0.01844933173157895 0.024023821791455388 6.398280519688471e-07 6.193936723069968 0.24464916363303457 REVS(ph)PAPAVAGQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 REVSPAPAVAGQSK 14 1 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 REVS(1)PAPAVAGQSK;REVS(1)PAPAVAGQSK 151.11 0.00035298 16863900.0 98373.0 98944.0 99668.0 110027.0 111552.0 85226.0 94669.0 81697.0 87423.0 74788.0 True False 115025.60594468526 108766.50642188422 102044.46311299493 103862.54390234701 89694.18638273233 80756.5985282017 85701.26697579374 79552.54031512685 88701.39598693319 88346.47237851788 1.3019830090313218 1.231135816672762 1.1550485306961482 1.1756275163693122 1.0152548706012867 0.9140896784446856 0.970058732040926 0.9004608579535165 1.0040174055495352 1.0 16.430884909531514 -6.118744838287814 1.2814627141487105 0.9477905574148086 1.2537069522124935 0.8875203235775053 0.04415787412287316 0.13511571721365262 0.4507419381154227 0.01678476576131234 0.027681607248351826 7.607731238752979e-07 6.118744838287814 0.30591639479768495 REVS(ph)PAPAVAGQSK ddPTM_PC-9_Lapatinib_30min_R1 5 REVSPAPAVAGQSK 14 1 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 REVS(1)PAPAVAGQSK;REVS(1)PAPAVAGQSK;REVS(1)PAPAVAGQSK;REVS(1)PAPAVAGQSK;REVS(1)PAPAVAGQSK 91.06700000000001 0.0021475 44751300.0 371467.0 325376.0 347857.0 292004.0 325349.0 306799.0 273424.0 304118.0 292534.0 217668.0 True False 366169.8124612946 324622.6118630422 319257.5402268513 313478.94825678883 306212.6114807445 293677.9219533996 287580.55684609275 318248.4325173422 259585.74040041448 255291.62377562153 1.4343197283398732 1.2715756477320088 1.250560184878804 1.2279249260927916 1.1994620385582175 1.15036254464626 1.1264786231249415 1.2466074202146722 1.0168204368058982 1.0 17.961786677533915 -1.5228787452803376 0.15473022055355964 0.9839143895624883 2.473636168923105 0.7837008715501319 0.05626995430148938 31.350918823471083 0.31672618131603286 0.18135057185140502 10.554622718027337 0.029999999999999995 1.5228787452803376 1.4897217793606163 RFDAQTGADR ddPTM_PC-9_AZD4547_30min_R2 1 RFDAQTGADR 10 1 P43686;P43686-2 P43686 PSMC4 26S protease regulatory subunit 6B 0 125.23 0.00024457 2520700.0 6118.4 7603.9 8657.9 10875.0 10408.0 9085.2 6778.7 9043.5 9168.4 8380.3 False True 8063.923929374132 10061.711972631067 8543.09058902864 8367.93676707512 8963.028855157338 8517.101007784535 7381.9911679180605 7646.0348739561205 9653.022906340431 8086.9082477648 0.9971578361363231 1.2441976172305524 1.0564099810814507 1.0347510458509277 1.1083381411721465 1.0531961964745475 0.9128323138769904 0.9454830745816195 1.1936604955309715 1.0 12.981372527717845 -7.004955139714159 21.658457529609272 1.0048171018618843 1.0909729213183932 0.1265215329397541 0.09197982630545957 71.394237098055 312064.2770600975 0.03288905468390604 0.0281014998957429 9.88655212152587e-08 7.004955139714159 0.08615581945650885 RFDAQTGADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RFDAQTGADR 10 1 P43686;P43686-2 P43686 PSMC4 26S protease regulatory subunit 6B 0 ;; 129.88 0.00014662 8942000.0 25170.4 23096.9 26679.300000000003 32764.9 38385.4 25392.0 27270.899999999998 31316.5 29182.5 24113.7 False True 29431.251581939225 25389.807589905642 27315.435693808675 30929.18887823904 30864.0564218995 24060.398819938706 24687.602927781783 30494.47505757452 29609.23885463404 28485.322926055836 1.0332075805613612 0.8913294630997954 0.9589301748383181 1.085793865090705 1.0835073382183007 0.8446595070168713 0.8666780078943659 1.070532889401822 1.0394559658493514 1.0 14.797931141074097 RFDAQTGADR ddPTM_PC-9_Lapatinib_30min_R1 3 RFDAQTGADR 10 1 P43686;P43686-2 P43686 PSMC4 26S protease regulatory subunit 6B 0 ;; 133.91 6.9913e-05 5139400.0 29235.699999999997 32291.2 35845.8 31196.199999999997 31311.7 34845.5 30512.300000000003 29840.600000000002 30712.699999999997 27123.1 False True 28818.793556829238 32216.431710365432 32898.69669278946 33490.47261547246 29470.007367170736 33355.23919382787 32092.077596169485 31227.10321446612 27253.512306931192 31811.291695741013 0.9059296878751887 1.012735729768517 1.0341829878349151 1.0527856880441062 0.9264008405894523 1.0485345742277281 1.008826611101305 0.9816358138845048 0.8567244790811174 1.0 14.957251333168632 -8.019998526244555 22.97629749962283 0.925301487941026 1.0011889631899018 0.1958043585322572 0.05579817444574111 384.15043371393796 441343.912478068 0.03504479302926774 0.01369664164334933 9.549958267439651e-09 8.019998526244555 0.07588747524887585 RFDDAVVQSDMK ddPTM_PC-9_AZD4547_30min_R2 2 RFDDAVVQSDMK 12 1 P11142;E9PKE3;P11142-2;E9PN89;E9PNE6;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PPY6;E9PN25 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 ; 159.66 0.00049799 74605000.0 154902.0 119735.0 174318.0 232893.0 190041.0 198835.0 185389.0 179282.0 145713.0 182628.0 False True 204157.61383824394 158436.99720445822 172006.42942264202 179203.1170109818 163657.08749644103 186401.81601757076 201888.26185391878 151578.08639051305 153415.0917010148 176234.24930763716 1.158444596554347 0.8990136583944487 0.9760102255855218 1.0168461449179618 0.9286338389920948 1.0576934775724833 1.145567689862029 0.8600943743115225 0.8705180309941407 1.0 17.42713479883522 -7.796867068764966 24.99999880164444 0.8989795791229706 1.0163396504192808 0.26775161621917265 0.08614846634056679 246.146120222554 173692.9511695239 0.046756024851562016 0.022462269061717832 1.596367697437075e-08 7.796867068764966 0.11736007129631021 RFDDAVVQSDMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RFDDAVVQSDMK 12 1 P11142;E9PKE3;P11142-2;E9PN89;E9PNE6;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PPY6;E9PN25 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 ;;; 148.13 0.00013438 99309300.0 264066.0 211016.0 270666.0 280494.0 300740.0 268805.0 309269.0 276778.0 265505.0 212354.0 False True 308767.15825876256 231964.27392383895 277119.7039465208 264778.83055381797 241812.15588015402 254708.39259584196 279972.80140633887 269512.8707705319 269387.50833888917 250852.09920666128 1.2308733282889082 0.9247053329728693 1.1047135137514608 1.0555176990393982 0.9639630549032806 1.0153727770322691 1.1160871377667319 1.0743895371929784 1.073889790800426 1.0 17.936477485500426 -1.5228787669458297 0.004637588951907719 1.1263427839206509e-08 2.1683686549529617 0.043523179348958774 0.08048038704463649 324883.0628319056 117.12498405579892 25565.89222961299 29316.389870275547 0.029999998503400863 1.5228787669458297 2.1683686436895337 RFDDAVVQSDMK ddPTM_PC-9_Lapatinib_30min_R1 5 RFDDAVVQSDMK 12 1 P11142;E9PKE3;P11142-2;E9PN89;E9PNE6;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PPY6;E9PN25 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 ;;;; 138.2 6.374600000000001e-05 131079200.0 346784.0 308505.0 350210.0 321757.0 357594.0 349842.0 307917.0 324201.0 314072.0 278737.0 False True 341838.7965676023 307790.67562699073 321417.08564969373 345420.08312988764 336561.0239768537 334880.07318153343 323859.43561054766 339264.5620139392 278697.9040352197 326916.3190562933 1.0456461688862324 0.9414968225369954 0.9831784677422217 1.056600918935491 1.0295020601859268 1.0243602220538548 0.9906493397008448 1.037771876892813 0.8525053287022645 1.0 18.318561870000096 -8.239469690203252 24.925301572197018 0.9262526283520575 1.0117801839542082 0.3631298499003768 0.04624430788126627 700.2827625001045 794495.771042286 0.030204550454488433 0.01139574512329902 5.761430266891482e-09 8.239469690203252 0.08552755560215075 RFDEILEASDGIMVAR ddPTM_PC-9_AZD4547_30min_R2 1 RFDEILEASDGIMVAR 16 1 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 75.877 0.026726999999999997 0.0 14664.0 11213.0 16494.0 29024.0 21964.0 18772.0 9595.5 21280.0 16375.0 14005.0 False True 19326.846969851977 14837.382967833904 16275.27878301186 22332.96521632995 18914.67772623708 17598.183872466347 10449.480911053408 17991.6649657529 17240.549069774934 13514.689212790237 1.4300622578550413 1.0978708229407064 1.2042658567101205 1.6524956560002977 1.3995643871955503 1.3021523170367477 0.7731943181619055 1.3312673848782017 1.2756896439363592 1.0 13.722240715223634 -7.023987081495829 24.95145001603071 1.1105048491353797 1.3504563408857235 0.28534840853054033 0.1967636605810113 1135.6894842278348 1181345.2473793563 0.07821031533637282 0.06093857402583326 9.462653085125658e-08 7.023987081495829 0.2399514917503438 RFDEILEASDGIMVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RFDEILEASDGIMVAR 16 1 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BR70 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 144.15 5.987300000000001e-08 0.0 6628.6 8277.5 9245.7 10266.0 11199.0 7705.3 9462.7 11316.0 9969.7 8469.4 False True 7750.691059182311 9099.235495908275 9466.152552512507 9690.829302821065 9004.636342694168 7301.220503594581 8566.324551984737 11018.966990293071 10115.488001680636 10004.83517626649 0.7746945274589362 0.9094837981432735 0.9461577712912405 0.9686145880553524 0.9000284546471092 0.7297691940907298 0.8562184584815357 1.1013641700397332 1.0110599348679565 1.0 13.288409779442611 -7.752605398386132 24.99998934333302 1.0421590443550568 0.873421295649749 0.5263613641779321 0.07299962433526082 156.01941989446308 441535.0784008196 0.037929676580284316 0.02147908710779958 1.7676431785566523e-08 7.752605398386132 -0.16873774870530778 RFDGVQDPR ddPTM_PC-9_AZD4547_30min_R2 2 RFDGVQDPR 9 1 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 0 ; 92.051 0.0046365 11703700.0 68665.0 79166.0 129350.0 128807.0 119924.0 63539.0 87757.0 113264.0 85098.0 72615.0 False True 90499.04167927493 104754.86132449284 127634.73448421125 99112.53619831215 103274.62263892093 59565.896285565694 95567.20299216466 95761.651347793 89596.10654898976 70072.77095228598 1.2915008276310014 1.4949438976206981 1.8214597874418355 1.4144229613211665 1.4738195911967402 0.850057668279243 1.3638279419153894 1.366602890771925 1.2786151500987113 1.0 16.096566326731143 -6.55486618974467 24.996897207519755 1.2017564391191013 1.5169770122872193 0.4108385884773271 0.19449898045041628 211.8313885905513 165536.31920366638 0.06553055010072122 0.06553103267398692 2.786979731286644e-07 6.55486618974467 0.3152205731681179 RFDGVQDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RFDGVQDPR 9 1 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 0 ; 74.376 0.017412999999999998 6429300.0 41920.0 42070.0 40542.0 41299.0 64276.0 40292.0 32563.0 38224.0 31811.0 27703.3 False True 49016.22804225962 46246.431569056 41508.67503639121 38985.15092316452 51681.579209126714 38179.0165899878 29478.396904295703 37220.66050167575 32276.1756945006 32725.688990797855 1.4977905600717072 1.4131537943191983 1.2683820055878134 1.1912705927788645 1.579235787019154 1.1666375183337887 0.9007723844281702 1.1373529985004087 0.9862642068002402 1.0 14.998135945842 -6.984472162240841 9.520058740352107 1.0197160930447207 1.3736662165390825 0.7113016808566948 0.11535954525209867 0.13533552965962467 75.02082197439152 0.041261684486042935 0.03590538138330641 1.0364010343741995e-07 6.984472162240841 0.35395012349436183 RFDGVQDPR ddPTM_PC-9_Lapatinib_30min_R1 2 RFDGVQDPR 9 1 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 0 ; 102.06 0.0020869 10484000.0 153024.0 151156.0 66776.0 43142.0 48162.0 59609.0 58600.0 50567.0 101537.0 23342.0 False True 150841.84969883546 150806.00756899698 61285.93504281421 46314.80659749309 45329.205850135164 57059.66202536582 61634.02126799786 52916.52742390933 90100.8338279888 27376.63359874006 5.509875754255541 5.508566530836627 2.238622028591373 1.6917641254337643 1.6557625935506302 2.084246838442249 2.251336748388027 1.9329084868325328 3.291158261041104 1.0 14.740657434290055 -5.27116269329226 5.44000094709027 2.0260865630319835 5.545934443596311 0.8677389655766554 0.545624009451954 0.04853865710175944 5.230086054876964 0.13839941001060085 0.3274084581730523 5.355959775596139e-06 5.27116269329226 3.519847880564327 RFEELGVK ddPTM_PC-9_AZD4547_30min_R2 1 RFEELGVK 8 1 Q04760-2;Q04760 Q04760-2 GLO1 Lactoylglutathione lyase 0 83.647 0.009338899999999999 4276400.0 34276.0 33511.0 44010.0 66627.0 48946.0 41666.0 34584.0 49685.0 39668.0 37277.0 False True 45175.055014910424 44342.77540667808 43426.39864437685 51267.17452688864 42150.692769459165 39060.618433314674 37661.909001914566 42007.32489771769 41764.76949617297 35971.943576235724 1.2558413731293236 1.2327044634856041 1.2072296997893044 1.4251989030906147 1.1717657868591045 1.0858634410601997 1.0469800977558323 1.1677802398608548 1.1610373347678713 1.0 15.13458449042795 -6.511604203523492 15.728000157254277 1.1031835998684552 1.274990283277688 0.6042962395923523 0.07136830946503578 3.128649219032878 4364.572698213051 0.022988854409307993 0.02459551446122358 3.0789015090004207e-07 6.511604203523492 0.17180668340923289 RFEELGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RFEELGVK 8 1 Q04760-2;Q04760 Q04760-2 GLO1 Lactoylglutathione lyase 0 ; 101.46 0.0028975999999999997 4565100.0 64917.0 62094.0 75014.0 80449.0 81724.0 81512.0 73079.0 75148.0 73071.0 58359.0 False True 75906.16593080554 68258.28195505029 76802.61825217918 75941.70334917707 65710.76886064261 77237.3672263249 66156.42807385765 73175.44462588777 74139.52513824934 68939.0247304103 1.1010623696468091 0.9901254365285542 1.1140659235102306 1.101577860234477 0.9531723014302573 1.1203722061396388 0.9596368433201059 1.0614516946249852 1.0754362340949248 1.0 16.073033268818122 RFEELGVK ddPTM_PC-9_Lapatinib_30min_R1 1 RFEELGVK 8 1 Q04760-2;Q04760 Q04760-2 GLO1 Lactoylglutathione lyase 0 85.29 0.008439 6288400.0 39916.0 35977.0 40604.0 35773.0 42611.0 36807.0 30872.0 37127.0 34850.0 30311.0 False True 39346.790520302085 35893.697466920305 37265.6958559726 38403.86575522971 40104.70475644928 35232.8504113077 32470.401102143886 38852.055958777106 30924.82601323076 35550.21596313128 1.1067946974248535 1.0096618682751533 1.0482551187486573 1.0802709551766974 1.1281142370004562 0.9910727531964161 0.9133671968636861 1.0928781979572255 0.8698913684603924 1.0 15.117570703613328 -6.908850833268037 7.525051086214291 0.9733711891898147 1.0695706539703704 0.4022288945242033 0.06187597666650877 0.2526011013505378 17.985980641575534 0.02095939918508496 0.01848123839374643 1.233528439371676e-07 6.908850833268037 0.09619946478055574 RFIGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 RFIGSPR 7 1 P23443-3;P23443-5;P23443-2;P23443;K7ERJ3;P23443-4 P23443-3 RPS6KB1 Ribosomal protein S6 kinase beta-1 1 RFIGS(1)PR 74.165 0.015853 3206700.0 3582.5 3528.5 4592.6 8499.9 8052.8 5835.6 5206.3 5181.9 5409.7 3447.1 True False 4721.660479370887 4669.018621421736 4531.699123248467 6540.379377145913 6934.807721446095 5470.699009490974 5669.65061406048 4381.156423215928 5695.645697878565 3326.4180782155827 1.419442886717284 1.403617498353176 1.3623360072884894 1.9661928306541738 2.0847673258095654 1.6446215962203 1.7044311571027464 1.3170793087939647 1.7122458945190457 1.0 11.699753788663978 -9.653386225482892 0.7497872519502419 0.9756416210136032 1.641635197845272 0.36486524665724196 0.24530699335221917 8.639343721140596 4.5921637852520645 0.9234638295212126 0.09481339173375689 2.2213335422121138e-10 9.653386225482892 0.6659935768316687 RFIGS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RFIGSPR 7 1 P23443-3;P23443-5;P23443-2;P23443;K7ERJ3;P23443-4 P23443-3 RPS6KB1 Ribosomal protein S6 kinase beta-1 1 RFIGS(1)PR 59.931000000000004 0.035343 3389300.0 8313.5 7899.6 9912.0 9335.7 15324.0 12531.0 12901.0 11913.0 12143.0 11661.0 True False 9720.811350890404 8683.82008136237 10148.339671469335 8812.650995747776 12321.372204254425 11873.852300435254 11678.923884848416 11600.296372866866 12320.568402700974 13775.04699157479 0.7056826272052595 0.6304022110903608 0.7367190600276244 0.6397546956564172 0.8944704298860487 0.861982707405473 0.8478318725149596 0.8421239056361793 0.8944120778852213 1.0 13.749769619899151 -6.26552932639842 24.99598091544813 0.8787200797410861 0.6789140718114355 0.8063138737396003 0.050716336475774074 147.22411662749383 899768.4520642036 0.014640654764898675 0.017208823629146865 5.425886109669895e-07 6.26552932639842 -0.19980600792965064 RFIGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 RFIGSPR 7 1 P23443-3;P23443-5;P23443-2;P23443;K7ERJ3;P23443-4 P23443-3 RPS6KB1 Ribosomal protein S6 kinase beta-1 1 RFIGS(1)PR;RFIGS(1)PR 85.86200000000001 0.0087099 9483600.0 16546.300000000003 12905.0 16937.8 13990.0 13694.099999999999 17327.6 13237.8 14796.5 18106.6 12359.2 True False 16310.346727780214 12875.119265380843 15545.239465798759 15018.871269271902 12888.639961636469 16586.538940608454 13923.188510947148 15483.999407278943 16067.244037049186 14495.471252401172 1.1252029301964508 0.8882166741042021 1.0724204267055957 1.0361078303531546 0.8891494272393158 1.1442566200019815 0.9605198940076387 1.0681956548817977 1.1084319893627226 1.0 13.823314616187849 -6.777479345461214 24.99992776770707 1.0545579479613367 1.0016686639220813 0.09439741249410805 0.08362925516911082 635.3478479191813 990249.0329567506 0.028070231279155766 0.02483643716686201 1.6692471927719633e-07 6.777479345461214 -0.05288928403925541 RFPEAEALS(ph)PEQAAHYLR ddPTM_PC-9_AZD4547_30min_R2 1 RFPEAEALSPEQAAHYLR 18 1 Q2NKX8 Q2NKX8 ERCC6L DNA excision repair protein ERCC-6-like 1 RFPEAEALS(1)PEQAAHYLR 68.134 0.004506399999999999 9740300.0 27332.0 19680.0 30336.0 47755.0 33447.0 27849.0 23718.0 35622.0 22376.0 30205.0 True False 36023.00745908305 26041.175136624537 29933.724818809704 36745.82255739515 28803.461387245115 26107.597627547166 25828.85605214578 30117.438412126376 23558.749678490625 29147.53214368646 1.2358853326416472 0.8934264145674926 1.0269728727374794 1.2606838334117603 0.9881955441460634 0.8957052521237973 0.8861421243081286 1.0332757594591075 0.8082588111526827 1.0 14.831086118385686 -6.51402114691343 23.799278844289674 0.9263035454680092 1.0887615070121468 0.3591714516193797 0.11248747336084791 274.60066090579545 737821.8822600648 0.035840308529113164 0.037706385675202146 3.061814342458956e-07 6.51402114691343 0.1624579615441376 RFPEAEALS(ph)PEQAAHYLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RFPEAEALSPEQAAHYLR 18 1 Q2NKX8 Q2NKX8 ERCC6L DNA excision repair protein ERCC-6-like 1 RFPEAEALS(1)PEQAAHYLR 69.398 0.00506 8240900.0 12964.0 11033.0 18670.0 15226.0 20336.0 19996.0 17561.0 16380.0 16427.0 14039.0 True False 15158.549149328588 12128.28332544319 19115.163606369286 14372.936583358038 16351.30678319747 18947.374559053802 15897.49494937005 15950.042356044583 16667.213798169232 16584.15956733715 0.9140378255394787 0.7313173318309177 1.1526157553390286 0.8666665636566738 0.9859593256327389 1.142498326919807 0.9585951512840302 0.9617636812575373 1.0050080458099102 1.0 14.0175182823141 -5.25030692063679 24.999736169853882 1.0048144166886974 0.8226775836716043 0.4066533250965423 0.08997147163072483 705.3084117035708 1583877.0833570415 0.0221193576940093 0.05739059341320564 5.61944052850751e-06 5.25030692063679 -0.18213683301709316 RFPEAEALS(ph)PEQAAHYLR ddPTM_PC-9_Lapatinib_30min_R1 2 RFPEAEALSPEQAAHYLR 18 1 Q2NKX8 Q2NKX8 ERCC6L DNA excision repair protein ERCC-6-like 1 RFPEAEALS(1)PEQAAHYLR;RFPEAEALS(1)PEQAAHYLR 118.37 4.596899999999999e-05 21187900.0 29693.0 22289.0 23342.8 21365.0 21585.0 17026.6 21627.6 17586.3 22751.3 15745.0 True False 29269.57237497068 22237.391189932092 21423.645089813755 22936.25337155069 20315.41273774277 16298.412008943184 22747.371303340453 18403.42369994457 20188.80901218986 18466.50227110625 1.585009004156003 1.2042015788082399 1.1601355132278852 1.2420464381843481 1.1001223967318072 0.8825933449478744 1.2318180762868287 0.9965841624886174 1.0932665382863778 1.0 14.172623011760765 -1.522878750012355 0.6842229392721 1.0626116964337529 56.70576780276744 0.6991906853951417 0.09973659827060904 148.5160482437147 0.8397371031828592 0.03970137122494485 12606.453994894242 0.029999999673123813 1.522878750012355 55.643156106333684 RFPGYDSESK ddPTM_PC-9_AZD4547_30min_R2 2 RFPGYDSESK 10 1 P46777;A0A2R8Y6J3 P46777 RPL5 60S ribosomal protein L5 0 ; 99.75200000000001 0.010142 15274000.0 186120.0 203895.0 226150.0 231290.0 243340.0 229670.0 209866.0 248130.0 221944.0 209133.0 False True 245302.2884635055 269800.07136595837 223151.10323621525 177969.6638948787 209556.44135414963 215308.6985930828 228543.66743568657 209787.20996016258 233675.50673234378 201811.31732513127 1.215503132900656 1.3368926725318024 1.1057412745426174 0.8818616629322027 1.038378046046548 1.0668811910394815 1.1324620961047875 1.0395215329880714 1.1578909935753365 1.0 17.62264755567505 -5.400001941749177 5.149843709162303 1.0474144777525805 1.2731292622456067 0.5887602154028159 0.07586952311806491 0.15025227059344193 5.625680697338793 0.02061572300467927 0.044115839629451745 3.98105390603314e-06 5.400001941749177 0.2257147844930263 RFPGYDSESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RFPGYDSESK 10 1 P46777;A0A2R8Y6J3 P46777 RPL5 60S ribosomal protein L5 0 ; 115.33 0.00071719 19068300.0 190529.0 169978.0 170814.0 231520.0 215373.0 209350.0 236620.0 193267.0 189129.0 172734.0 False True 222781.79658071807 186852.29249453303 174886.85357570276 218548.68499796785 173172.20671801717 198371.31746038797 214205.6406195517 188193.94603331335 191894.65382808435 204049.30683840797 1.0918037411278483 0.9157212802614727 0.8570813411985774 1.0710582083527602 0.8486782405742589 0.9721734444189191 1.049773919541843 0.9222964240812105 0.9404327650083654 1.0 17.63855828416299 -6.975164437162399 24.99838982446793 0.9772681907710281 0.9508870778675946 0.01296905937165771 0.08058161213434366 1179.7671788247328 1187497.8039882372 0.028049366715816603 0.02473635815517617 1.0588527352656429e-07 6.975164437162399 -0.02638111290343348 RFQDAVR ddPTM_PC-9_AZD4547_30min_R2 2 RFQDAVR 7 1 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 0 ; 145.34 0.0010402999999999999 8314000.0 17407.0 15629.5 20133.7 32101.0 22859.4 21805.3 20211.1 22432.2 19582.4 21467.2 False True 22942.0639119076 20681.430223469164 19866.713982874113 24700.610405506046 19685.76689196614 20441.811143953255 22009.84874591125 18965.818930674912 20617.485685738066 20715.63986210713 1.1074755143756396 0.9983486081595508 0.9590200503154206 1.192365312871083 0.9502852445303983 0.9867815466972487 1.0624749654086947 0.9155314080047812 0.9952618322667113 1.0 14.338432762339751 RFQDAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RFQDAVR 7 1 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 0 ; 131.03 0.0027561 6624300.0 16145.6 14734.9 20470.7 20567.1 22933.4 21830.4 19646.0 20327.9 20606.0 16969.4 False True 18878.73118986421 16197.683492438397 20958.799123562065 19414.79206643787 18439.764898789388 20685.575393777155 17784.988655277273 19794.314164190408 20907.323767277972 20045.817890303522 0.9417790430489819 0.8080330561255608 1.0455447235056528 0.9685208242777218 0.9198808948428586 1.031914761820873 0.8872169124054625 0.9874535562734623 1.0429768384452487 1.0 14.291013661703268 -1.5228787502357555 0.29993594509198174 0.9958962683113358 0.07533457624463595 0.16983390328918868 0.06571733489084595 94.58489284001394 1.3478683264282363 0.06623459125485143 46.71340723504272 0.02999999965769186 1.5228787502357555 -0.9205616920666999 RFQDAVR ddPTM_PC-9_Lapatinib_30min_R1 2 RFQDAVR 7 1 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 0 ; 122.18 0.0033537 9479200.0 19492.4 14636.8 17828.2 14652.599999999999 14937.699999999999 16561.300000000003 16116.5 13570.8 16254.1 14974.4 False True 19214.434801531625 14602.909388882308 16362.434214842151 15730.201083640704 14059.093854648154 15853.011805275908 16950.933511359857 14201.348910641109 14423.392094738996 17562.705087866223 1.0940475687202966 0.8314726755260049 0.9316579725606553 0.8956593534391485 0.8005084515346867 0.9026520530842648 0.96516643800339 0.8086082889618514 0.821251169599373 1.0 14.100227452001588 -4.753321291561666 24.993682277094393 0.8804744287757051 1.0940479615755205 0.48337111770539887 0.06501473896988869 256.21500377236464 788763.6862185101 0.015803567879668377 0.17236711832970542 1.7647317870192935e-05 4.753321291561666 0.2135735327998154 RFS(ph)DFLGLHSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RFSDFLGLHSK 11 1 O60749;O60749-2;D6RC15 O60749 SNX2 Sorting nexin-2 1 RFS(1)DFLGLHSK 80.507 0.02603 0.0 18148.0 13489.0 11954.0 15312.0 13422.0 11784.0 13496.0 12951.0 13327.0 11540.0 True False 21220.097960661442 14828.098774304646 12239.02869579745 14454.118282173788 10792.055450633181 11166.026295453588 12217.561177421463 12611.049972718773 13521.882162793045 13632.11064941027 1.5566260065222866 1.087733158544023 0.8978087847553463 1.0602993662466405 0.7916643084979691 0.8190973931052001 0.8962340089243627 0.925098856446293 0.9919140557576098 1.0 13.734721330371643 -4.639274956860455 1.7866606624095445 0.9123787730112068 1.9616828236679615 0.8569843692352048 0.07788100370706928 0.47332721020084834 1.1477578193878764 0.021819793329588794 0.9488454687017445 2.2946953899269903e-05 4.639274956860455 1.0493040506567546 RFS(ph)DGAASIQAFK ddPTM_PC-9_AZD4547_30min_R2 2 RFSDGAASIQAFK 13 1 H0Y4E8;Q9Y2K2-7;Q9Y2K2;Q9Y2K2-8 H0Y4E8 SIK3 Serine/threonine-protein kinase SIK3 1 RFS(0.998)DGAAS(0.002)IQAFK;RFS(0.999)DGAAS(0.001)IQAFK 131.72 9.533799999999999e-05 47712000.0 100433.0 90602.0 133414.0 168117.0 170804.0 128795.0 112688.0 197065.0 139303.0 134035.0 True False 132368.604863826 119887.32468132397 131644.84318884113 129360.22303175803 147090.81289164987 120741.42828970314 122717.013694418 166613.13235319973 146666.27218728888 129342.47544707876 1.023396254063387 0.9268983314794882 1.0178005541783866 1.0001372138937183 1.1372197136572737 0.9335017585859118 0.9487758237983345 1.2881548136240093 1.1339374144520549 1.0 16.980836601509765 -7.742380362331676 24.99995986576992 1.1582846643017692 0.9991825470696902 0.3584994757122508 0.08636032798331392 220.45354768855876 289172.4948933125 0.039766147240628956 0.02291277015470777 1.8097543853308817e-08 7.742380362331676 -0.159102117232079 RFS(ph)DGAASIQAFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RFSDGAASIQAFK 13 1 H0Y4E8;Q9Y2K2-7;Q9Y2K2;Q9Y2K2-8 H0Y4E8 SIK3 Serine/threonine-protein kinase SIK3 1 RFS(1)DGAASIQAFK;RFS(0.997)DGAAS(0.003)IQAFK 154.47 7.6609e-05 28430800.0 145781.0 115466.0 133396.0 143196.0 157270.0 128260.0 101990.0 149905.0 91065.0 93390.0 True False 170458.8439940043 126928.70139179012 136576.66654714724 135173.19236769588 126454.07247214108 121533.81981117422 92328.76885634384 145970.15258747616 92396.6533469458 110320.86772516678 1.5451187749778605 1.1505411805497856 1.2379948541321244 1.2252731070285054 1.1462389217891724 1.101639447887061 0.8369111915105204 1.3231418098624774 0.8375265283185218 1.0 16.751346183916496 -1.5228787452803465 0.32532086931138143 1.0032513268683827 5.534468365683252 0.4989115320719314 0.14491750904011882 50.789190620350716 0.724066615038261 0.12825578081585937 137.69488982124912 0.02999999999999938 1.5228787452803465 4.531217038814869 RFS(ph)DGAASIQAFK ddPTM_PC-9_Lapatinib_30min_R1 1 RFSDGAASIQAFK 13 1 H0Y4E8;Q9Y2K2-7;Q9Y2K2;Q9Y2K2-8 H0Y4E8 SIK3 Serine/threonine-protein kinase SIK3 1 RFS(1)DGAASIQAFK 103.67 0.00066001 17833000.0 241950.0 176280.0 204360.0 184290.0 172680.0 141770.0 125390.0 97263.0 171950.0 167670.0 True False 238499.74863180445 175871.8344906107 187558.30965241237 197843.3013734185 162523.30190194215 135706.82758201144 131882.08066201792 101782.19405603854 152583.18028622755 196651.536093769 1.2128038934721619 0.8943323707715664 0.953759697879905 1.0060602897049389 0.8264532539651581 0.6900878085045956 0.6706384464707807 0.5175763997465339 0.7759063738687074 1.0 17.58528193000931 -6.4531896431984235 2.345977890278731 0.6959362627797905 1.0076022837933096 0.4798942385679794 0.1378344662828237 0.24259995929008826 2.6417509102768633 0.04671565378064403 0.0524809662863702 3.522170349847957e-07 6.4531896431984235 0.31166602101351915 RFS(ph)DIQIR ddPTM_PC-9_AZD4547_30min_R2 2 RFSDIQIR 8 1 V9GZ78;V9GYY3;A0A384N5Y3;F5H2F4;P11586;A0A494C1T2 V9GZ78 MTHFD1 C-1-tetrahydrofolate synthase, cytoplasmic;Methylenetetrahydrofolate dehydrogenase;Methenyltetrahydrofolate cyclohydrolase;Formyltetrahydrofolate synthetase;C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed 1 RFS(1)DIQIR;RFS(1)DIQIR 85.81299999999999 0.0059342 6446800.0 13923.099999999999 11917.400000000001 20371.6 28635.0 21181.2 20190.6 15656.7 18441.1 15834.5 16094.8 True False 18350.35618152933 15769.466492541134 20101.459273433025 22033.643156339847 18240.555994125538 18928.07859020983 17050.115968953138 15591.451729320761 16671.479343227555 15531.325950875851 1.1815060890209768 1.0153329176413206 1.2942526180322327 1.4186582154048035 1.174436493820214 1.2187033257867095 1.0977888187319667 1.0038712585541687 1.0734099197942213 1.0 13.922893381270427 -7.4075599716018035 2.685381030351984 1.0289074251916301 1.2200610948346744 0.4449858126782411 0.09708609817202807 0.3019374157231539 4.2241005291849225 0.052944063866002394 0.031949468788510724 3.912370975766597e-08 7.4075599716018035 0.19115366964304426 RFS(ph)DIQIR ddPTM_PC-9_Lapatinib_30min_R1 2 RFSDIQIR 8 1 V9GZ78;V9GYY3;A0A384N5Y3;F5H2F4;P11586;A0A494C1T2 V9GZ78 MTHFD1 C-1-tetrahydrofolate synthase, cytoplasmic;Methylenetetrahydrofolate dehydrogenase;Methenyltetrahydrofolate cyclohydrolase;Formyltetrahydrofolate synthetase;C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed 1 RFS(1)DIQIR;RFS(1)DIQIR 89.9 0.0045284999999999995 7459700.0 31374.0 27764.0 29752.0 28361.0 33157.0 27240.0 23797.1 21228.0 27155.0 21561.0 True False 30926.60100671305 27699.714163815068 27305.905406041216 30446.762549522526 31206.770449170137 26075.008699541435 25029.197397895445 22214.33037662402 24096.517945173055 25287.790121773385 1.2229855142654207 1.095378996362555 1.0798059171857088 1.2040104098818483 1.23406475215485 1.0311303824484939 0.989774008617096 0.878460722334806 0.9528914084281878 1.0 14.62615334618047 -7.03228606331077 2.9254479339307315 0.9452307754109296 1.1598914661089383 0.7498769371907219 0.05751554285687378 0.13910727216167762 2.3903935468385904 0.024547394030117037 0.01940105532866248 9.283546919278629e-08 7.03228606331077 0.21466069069800875 RFS(ph)DQAAGPAIPTSNSYSK ddPTM_PC-9_AZD4547_30min_R2 1 RFSDQAAGPAIPTSNSYSK 19 1 Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 RFS(1)DQAAGPAIPTSNSYSK 73.057 0.0023663 7148800.0 25429.0 15986.0 36607.0 42529.0 38140.0 28738.0 24000.0 45931.0 29762.0 34910.0 True False 33514.89304394202 21153.16187673171 36121.56726141111 32724.596116499997 32844.91934432175 26941.008317011387 26135.953505839378 38833.419339379536 31335.15855967276 33687.81152577703 0.9948670313088549 0.6279173659157367 1.0722444001377718 0.9714075991983032 0.9749793131913504 0.7997256899990915 0.7758281800478737 1.1527439029295572 0.9301630809616681 1.0 15.039939088701882 -7.759214346108154 24.99999378064943 1.0310901007854225 0.8883532058110543 0.1901766654858017 0.1318557560106845 97.51496194358894 1095698.9936127835 0.06548168711943149 0.03544191635867511 1.7409474164520986e-08 7.759214346108154 -0.14273689497436826 RFS(ph)DQAAGPAIPTSNSYSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RFSDQAAGPAIPTSNSYSK 19 1 Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 RFS(1)DQAAGPAIPTSNSYSK;RFS(1)DQAAGPAIPTSNSYSK 106.44 0.00010149999999999999 13138500.0 56031.0 58238.0 58655.0 60414.0 64842.0 52438.0 57100.0 56164.0 49641.0 46295.0 True False 65515.94163730557 64019.48375846646 60053.55765032624 57029.19944483067 52136.675572191714 49688.05896817683 51691.07463179942 54689.75451067693 50366.9057134546 54687.91702898167 1.1979966544087908 1.1706330618615362 1.0981138231778158 1.0428116948504045 0.9533490833918956 0.9085747212102597 0.9452010140449474 1.0000335994090668 0.9209878241799343 1.0 15.738934492860174 -5.716917231466492 1.364241221533958 0.9508555123683164 1.1943871077821906 0.906367400891385 0.029652744139805745 0.1274701306429911 0.46914269776309947 0.010216463796287992 0.026399361694017416 1.91903443845883e-06 5.716917231466492 0.24353159541387415 RFS(ph)DQAAGPAIPTSNSYSK ddPTM_PC-9_Lapatinib_30min_R1 2 RFSDQAAGPAIPTSNSYSK 19 1 Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 RFS(1)DQAAGPAIPTSNSYSK;RFS(1)DQAAGPAIPTSNSYSK 113.52 3.9988000000000004e-05 11321100.0 62045.0 55683.0 60012.0 59626.0 56526.0 60867.0 40646.0 45392.0 69438.0 63110.0 True False 61160.22692234049 55554.06943465332 55078.04501301914 64011.094946505065 53201.25181439188 58263.86029790707 42750.45099759457 47501.07803164303 61617.161225443764 74018.47941121079 0.8262832120957783 0.7505432410468991 0.7441120845921763 0.8647988374753074 0.7187563462204014 0.7871528942687583 0.5775645668170754 0.6417462018876403 0.8324564583815439 1.0 16.17559787767828 -8.53578992687684 19.654034570977625 1.0000000052589542 0.7390625241639757 0.5099565538339137 0.0786456961509594 86.15375890183738 131149.2649277441 0.08087412748060786 0.020881609928387047 2.9121254052331033e-09 8.53578992687684 -0.2609374810949785 RFS(ph)DQAGPAIPTSNSYSK ddPTM_PC-9_AZD4547_30min_R2 4 RFSDQAGPAIPTSNSYSK 18 1 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4 E9PC69 MARK2 Serine/threonine-protein kinase MARK2 1 RFS(1)DQAGPAIPTSNSYSK;RFS(1)DQAGPAIPTSNSYSK;RFS(0.978)DQAGPAIPT(0.017)S(0.003)NS(0.001)Y(0.001)SK;RFS(1)DQAGPAIPTSNSYSK 104.67 0.00016525 82830000.0 160488.0 152021.0 194495.0 261233.0 246312.0 177181.0 178728.0 244008.0 178971.0 224651.0 True False 211519.8456422264 201158.81531731723 191915.86921922458 201009.76785961704 212115.83045460397 166101.84406070007 194634.44575798546 206302.1703460262 188431.04168346192 216786.03686844272 0.9757078855156519 0.9279140770463509 0.8852778158202566 0.9272265444918874 0.9784570700156631 0.7662017649296273 0.8978181831706255 0.9516395674100602 0.8692028527548197 1.0 17.725912310513323 -4.841828999306155 3.1125464083002337 0.9052780657933914 0.981823527192096 0.09132634149867835 0.06172294026384924 0.7339864645076378 11.390946870660141 0.015576038034357658 0.12905005693264116 1.4393652076035945e-05 4.841828999306155 0.07654546139870455 RFS(ph)DQAGPAIPTSNSYSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RFSDQAGPAIPTSNSYSK 18 1 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4 E9PC69 MARK2 Serine/threonine-protein kinase MARK2 1 RFS(1)DQAGPAIPTSNSYSK;RFS(1)DQAGPAIPTSNSYSK;RFS(1)DQAGPAIPTSNSYSK;RFS(1)DQAGPAIPTSNSYSK;RFS(0.992)DQAGPAIPT(0.005)S(0.002)NS(0.001)YSK 96.50399999999999 0.00038066 63042300.0 234216.0 232389.0 228301.0 217245.0 263195.0 246724.0 210790.0 242026.0 213188.0 176818.0 True False 273864.1428231362 255459.04411460366 233744.56167636407 205073.4669677929 211623.82911111653 233785.35910722078 190822.44521255718 235673.07394774427 216305.47118792846 208873.70370948224 1.3111470614034195 1.22303114072184 1.1190712738137403 0.9818060546914272 1.0131664510792577 1.1192665948624514 0.913578118373234 1.1283041845972945 1.0355801967718392 1.0 17.672271349245335 -5.2516519561566835 1.9602359113602095 1.031418979236774 1.3048684540259292 0.7143050329206161 0.060770277202577126 0.2009400200036985 1.374243477837817 0.016645095014573112 0.0690017900026514 5.602063713515857e-06 5.2516519561566835 0.27344947478915516 RFS(ph)DQAGPAIPTSNSYSK ddPTM_PC-9_Lapatinib_30min_R1 5 RFSDQAGPAIPTSNSYSK 18 1 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4 E9PC69 MARK2 Serine/threonine-protein kinase MARK2 1 RFS(1)DQAGPAIPTSNSYSK;RFS(1)DQAGPAIPTSNSYSK;RFS(1)DQAGPAIPTSNSYSK;RFS(1)DQAGPAIPTSNSYSK;RFS(1)DQAGPAIPTSNSYSK 147.84 4.2396000000000005e-05 83087800.0 227771.0 207327.0 252871.0 189590.0 206227.0 210525.0 193110.0 200126.0 264582.0 236290.0 True False 224522.94377191403 206846.94706963244 232080.9224902881 203533.08105369945 194097.13331788205 201521.33650774442 203108.29090551322 209424.5845558818 234781.98898802328 277132.41166336584 0.8101648682097972 0.7463830947384476 0.8374369533225078 0.7344253955431678 0.7003768781605121 0.7271662498738451 0.7328925898145393 0.7556841991122674 0.8471834368951914 1.0 18.08021592365929 -8.603078274017786 2.256912690550559 0.9996114442800749 0.7533578847474136 0.7937046346145176 0.038387119032539725 0.1787039181738224 2.0589937372876768 0.03929478314523699 0.010764933508202042 2.494145160197496e-09 8.603078274017786 -0.24625355953266126 RFS(ph)DSEER ddPTM_PC-9_AZD4547_30min_R2 1 RFSDSEER 8 1 O75113 O75113 N4BP1 NEDD4-binding protein 1 1 RFS(0.993)DS(0.007)EER 83.0 0.023025 37447000.0 16045.0 17231.0 23012.0 39056.0 27383.0 27441.0 19975.0 25033.0 21644.0 28107.0 True False 21146.97624326752 22800.583779429762 22706.845844226304 30052.242609184883 23581.343114985906 25725.109932045005 21752.736303297574 21164.725051113368 22788.05765289825 27122.982485104956 0.7796700180328893 0.84063704247684 0.8371810090094683 1.1079991894581867 0.8694229378327402 0.9484616946595893 0.8020038472997376 0.7803244006346401 0.8401752154436812 1.0 14.72722820772465 -10.208089414371692 14.98429729739095 0.9999942743768234 0.8706957701739565 0.15397335979346938 0.0930008574106637 0.0 0.0 0.09522147051718331 0.023094598868763815 6.193135550746176e-11 10.208089414371692 -0.12929850420286693 RFS(ph)DSEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RFSDSEER 8 1 O75113 O75113 N4BP1 NEDD4-binding protein 1 1 RFS(0.995)DS(0.005)EER 62.633 0.028047000000000002 16464000.0 19725.0 19332.0 22875.0 21791.0 25980.0 29264.0 26879.0 26239.0 19845.0 17368.0 True False 23064.05291349169 21251.15319926291 23420.426753920598 20570.12091737521 20889.405498990487 27729.34432367225 24332.826532892057 25550.254052518572 20135.195581948527 20516.68091498765 1.1241610184931599 1.0357987867198695 1.1415309742820892 1.0026047099240365 1.0181669045566994 1.351551181137475 1.1860020942820568 1.2453405186924678 0.9814060892880366 1.0 14.324509737453942 -5.288543102737583 24.194365573716237 1.127981174564413 1.079979863658344 0.006343779299993191 0.11698401658724822 2158.085365426472 1926428.5549262057 0.03186079219982199 0.06635074665255788 5.145847331172489e-06 5.288543102737583 -0.04800131090606907 RFS(ph)DSEER ddPTM_PC-9_Lapatinib_30min_R1 1 RFSDSEER 8 1 O75113 O75113 N4BP1 NEDD4-binding protein 1 1 RFS(0.622)DS(0.378)EER 83.081 0.022856 25297000.0 52447.0 49348.0 59991.0 40409.0 63127.0 46140.0 48310.0 42912.0 55965.0 45372.0 True False 51699.09616239816 49233.73773793207 55058.771551956794 43380.81266047236 59413.993972457174 44166.69975759329 50811.2554173546 44905.848177957916 49661.63236242348 53214.48974561025 0.9715229143329877 0.9251942088196653 1.0346575118010726 0.8152067767228928 1.1165003038924814 0.8299750682329275 0.9548387226910525 0.8438650524063753 0.9332351507987569 1.0 15.699531509446384 RFS(ph)DSEGEETVPEPR ddPTM_PC-9_Lapatinib_30min_R1 2 RFSDSEGEETVPEPR 15 1 A0A1B0GV41;A0A1B0GWH8;H3BR84;A0A1B0GWD3;A0A1B0GV71;A0A1B0GW34;A0A0D9SFH9;H3BPL0;Q9UBD8;H3BQ48;O95090;H3BR00;Q9UP10;Q9UBH5;A0A0D9SF04;Q13286-5;Q13286-4;Q13286-6;Q13286-2;Q13286-7;Q13286-3;Q13286 A0A1B0GV41 CLN3 Battenin 1 RFS(0.915)DS(0.085)EGEETVPEPR;RFS(0.996)DS(0.003)EGEET(0.001)VPEPR 116.61 0.0011866 3131000.0 13328.2 20788.2 28844.0 23287.1 24330.1 23656.0 17162.8 21303.3 25448.0 21047.8 True False 13138.137423907474 20740.066200123212 26472.557661059844 24999.711017488335 22899.051352817034 22644.28802482938 18051.405805774637 22293.129089520207 22581.778260679952 24685.884185569405 0.5322125521267582 0.8401589363465947 1.0723763208990047 1.0127128050006158 0.9276172237007861 0.9172970210265559 0.7312440449804477 0.9030719305793419 0.9147648142123487 1.0 14.591398699219967 -4.799479333990032 3.6996671517128936 0.927603996822559 0.497665891251248 0.6636250443767409 0.08579519604581834 0.16393079210002587 3.8909723584521894 0.02373721500909779 0.18798488879396213 1.5867944251589112e-05 4.799479333990032 -0.429938105571311 RFS(ph)EDSSTSK ddPTM_PC-9_AZD4547_30min_R2 1 RFSEDSSTSK 10 1 Q14207 Q14207 NPAT Protein NPAT 1 RFS(0.998)EDSS(0.001)T(0.001)SK 76.262 0.034342000000000004 10500000.0 29564.0 31037.0 42228.0 53913.0 37456.0 37519.0 31251.0 37031.0 27682.0 31594.0 True False 38964.737030599004 41069.10328838499 41668.02912871497 41484.19079754672 32255.880937622307 35172.93099888476 34032.278458791116 31308.709837725368 29145.214006076938 30487.90367646515 1.2780392330049726 1.3470622225852773 1.3667069264877076 1.3606770487657387 1.057989466245983 1.1536683981993874 1.1162551161253509 1.0269223548450737 0.9559599215270189 1.0 14.895949334766197 -6.605165836348299 0.8781412173776271 1.0065812132586816 1.3552800995579217 0.8154157908262101 0.06499051014851619 0.2560028371671701 0.4337353952263501 0.04026105085633265 0.044438995314570386 2.482185096210739e-07 6.605165836348299 0.3486988862992402 RFS(ph)EDSSTSK ddPTM_PC-9_Lapatinib_30min_R1 2 RFSEDSSTSK 10 1 Q14207 Q14207 NPAT Protein NPAT 1 RFS(0.994)EDS(0.003)S(0.002)T(0.001)SK;RFS(0.999)EDSS(0.001)TSK 85.536 0.017397 16455800.0 56026.0 48562.0 58601.0 44859.0 54283.0 67385.0 75370.0 62189.0 78965.0 59430.0 True False 55227.058966089906 48449.557672640374 53783.05198640163 48158.08050523719 51090.18066448421 64503.100632107235 79272.28981175761 65078.527972106305 70071.13016168623 69702.39631450281 0.7923265466642062 0.6950917075222505 0.7716097986606971 0.6909099694068488 0.7329759572965212 0.9254072175806419 1.137296477642959 0.9336627062069253 1.0052901172223645 1.0 16.088920635236 -6.870159435060712 3.7683104857562464 1.015669272704399 0.7330418270687612 0.8532105722005124 0.055640534124963364 0.07983759603780297 2.1475073654272583 0.019787111939576447 0.017430939376711824 1.348467751948651e-07 6.870159435060712 -0.2826274456356378 RFS(ph)EGVLQSPSQDQEK ddPTM_PC-9_AZD4547_30min_R2 4 RFSEGVLQSPSQDQEK 16 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RFS(1)EGVLQSPSQDQEK;RFS(1)EGVLQSPSQDQEK;RFS(0.999)EGVLQS(0.001)PSQDQEK;RFS(0.999)EGVLQS(0.001)PSQDQEK 115.38 8.1213e-05 347358500.0 158144.0 132959.5 173448.0 230156.0 258634.0 183979.0 184634.0 308254.0 242281.0 234253.0 True False 208430.50240045434 175936.05821026574 171147.96619108997 177097.09007475295 222727.13344780586 172474.76404605174 201066.06831654767 260620.427272237 255087.4790335351 226051.8737710637 0.9220472227164302 0.7782994906224345 0.7571181045126916 0.783435620861563 0.9852921355271533 0.7629875442692737 0.8894687089396983 1.1529231008993226 1.128446647126126 1.0 17.786294350815304 -7.662815699001684 4.834514197256767 1.1045377631362114 0.8304868188247044 0.6892134435186517 0.07865343333228006 0.11218995006867867 4.350740285503033 0.03894658399588252 0.021557619914365417 2.1736234009738856e-08 7.662815699001684 -0.274050944311507 RFS(ph)EGVLQSPSQDQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 RFSEGVLQSPSQDQEK 16 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RFS(1)EGVLQSPSQDQEK;RFS(1)EGVLQSPSQDQEK;RFS(1)EGVLQSPSQDQEK;RFS(1)EGVLQSPSQDQEK;RFS(1)EGVLQSPSQDQEK;RFS(1)EGVLQSPSQDQEK 220.16 8.9205e-23 436371800.0 462992.0 398274.0 352169.0 394414.0 398914.0 288292.0 217733.0 329003.0 230803.0 177829.0 True False 541367.4010911713 437812.01061883057 360566.04456836905 372316.2622874414 320749.6653281093 273173.4600109394 197107.75398958952 320367.0198574936 234178.0572386227 210067.9900064102 2.5771056364877465 2.0841443315826975 1.7164254513853654 1.7723607593716693 1.5268850114590122 1.3004049784196228 0.9383045650295164 1.5250634799129446 1.1147726849363238 1.0 17.680496816470054 -1.5228787452804835 0.3007754383120076 1.0562470056448923 14.22103796835119 0.8879487549125363 0.1621553970748949 17.03737723511389 0.24284824738975036 0.1688949043252 120.78501227796744 0.02999999999998992 1.5228787452804835 13.164790962706299 up RFS(ph)EGVLQSPSQDQEK ddPTM_PC-9_Lapatinib_30min_R1 5 RFSEGVLQSPSQDQEK 16 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RFS(1)EGVLQSPSQDQEK;RFS(0.999)EGVLQS(0.001)PSQDQEK;RFS(1)EGVLQSPSQDQEK;RFS(1)EGVLQSPSQDQEK;RFS(1)EGVLQSPSQDQEK 235.85 2.3769e-37 81583000.0 272657.0 220762.0 261481.0 226943.0 182999.0 133308.0 134855.0 121973.0 152879.0 186805.0 True False 268768.86118082947 220250.83915257646 239983.0415258495 243633.14527965506 172235.35860987677 127606.72759612587 141837.13204941744 127640.31086432846 135660.15713276036 219093.99534798396 1.226728558918046 1.0052801255586905 1.0953428511114043 1.1120028410303802 0.7861254177063033 0.5824291413986489 0.6473802799759049 0.5825824238660632 0.6191870156792441 1.0 17.741190419739866 -6.374029915030909 3.308933568855806 0.6589257977074122 1.103613865403539 0.718516780511139 0.1251495020368659 0.12388027913687033 2.546830539230101 0.038473072408242416 0.04439174080455662 4.226395010492936e-07 6.374029915030909 0.4446880676961268 RFS(ph)FCCSPEPEAEAEAAAGPGPCER ddPTM_PC-9_AZD4547_30min_R2 8 RFSFCCSPEPEAEAEAAAGPGPCER 25 1 Q13501;E7EMC7;E3W990;D6RBF1;C9J6J8 Q13501 SQSTM1 Sequestosome-1 1 RFS(0.777)FCCS(0.223)PEPEAEAEAAAGPGPCER;RFS(0.5)FCCS(0.5)PEPEAEAEAAAGPGPCER;RFS(0.795)FCCS(0.205)PEPEAEAEAAAGPGPCER;RFS(0.758)FCCS(0.242)PEPEAEAEAAAGPGPCER;RFS(0.5)FCCS(0.5)PEPEAEAEAAAGPGPCER;RFS(0.819)FCCS(0.181)PEPEAEAEAAAGPGPCER;RFS(0.837)FCCS(0.163)PEPEAEAEAAAGPGPCER;RFS(0.968)FCCS(0.032)PEPEAEAEAAAGPGPCER 145.03 3.784199999999999e-09 2501086600.0 185156.7 116560.0 228020.39999999997 289847.3 249547.6 192651.69999999998 213602.7 229243.1 219006.5 232298.2 True False 244032.67910139007 154235.74054496727 224996.70051011755 223027.4830811452 214902.2232451254 180605.15874404582 232612.92649674037 193818.84637737743 230582.73647936896 224165.51072406917 1.0886272304474878 0.6880440262499605 1.0037079289466233 0.9949232705814197 0.958676571391278 0.8056777251802895 1.0376838334558491 0.8646238475817709 1.0286271770111812 1.0 17.774204801933827 -8.284039450050932 23.94119261832804 1.0143136382765652 0.9271535513427237 0.08185046873205104 0.11224400651914107 1344.8727494609054 1424657.2694351722 0.10123736146156806 0.026234450899415097 5.1994876375087595e-09 8.284039450050932 -0.08716008693384147 RFS(ph)FCCSPEPEAEAEAAAGPGPCER ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 RFSFCCSPEPEAEAEAAAGPGPCER 25 1 Q13501;E7EMC7;E3W990;D6RBF1;C9J6J8 Q13501 SQSTM1 Sequestosome-1 1 RFS(0.5)FCCS(0.5)PEPEAEAEAAAGPGPCER;RFS(0.878)FCCS(0.122)PEPEAEAEAAAGPGPCER;RFS(0.824)FCCS(0.176)PEPEAEAEAAAGPGPCER;RFS(0.5)FCCS(0.5)PEPEAEAEAAAGPGPCER;RFS(0.578)FCCS(0.422)PEPEAEAEAAAGPGPCER;RFS(0.5)FCCS(0.5)PEPEAEAEAAAGPGPCER;RFS(0.894)FCCS(0.106)PEPEAEAEAAAGPGPCER 139.45 8.950900000000001e-08 1486144000.0 163183.6 175888.1 189580.9 214691.3 227657.5 183479.5 195711.9 242339.2 188874.7 121787.29999999999 True False 190807.36045698667 193349.1081640425 194101.22764556683 202662.8424995856 183049.64712803822 173857.51202280022 177172.65200054788 235978.0527796071 191636.63517167297 143866.37342226357 1.3262818539044294 1.3439492743487853 1.349177177601179 1.4086880601678053 1.272358806117726 1.2084652437335677 1.2315084323459433 1.6402585758312378 1.3320460550513666 1.0 17.134369897883495 -6.276029378869462 24.172659727249776 1.3067071863107336 1.3555296903994352 0.04195135906398351 0.1504359472829093 2854.0810648719666 4728623.522895647 0.04773000543832076 0.054399024530571424 5.296276147768289e-07 6.276029378869462 0.04882250408870159 RFS(ph)FCCSPEPEAEAEAAAGPGPCER ddPTM_PC-9_Lapatinib_30min_R1 3 RFSFCCSPEPEAEAEAAAGPGPCER 25 1 Q13501;E7EMC7;E3W990;D6RBF1;C9J6J8 Q13501 SQSTM1 Sequestosome-1 1 RFS(0.5)FCCS(0.5)PEPEAEAEAAAGPGPCER;RFS(0.5)FCCS(0.5)PEPEAEAEAAAGPGPCER;RFS(0.804)FCCS(0.196)PEPEAEAEAAAGPGPCER 150.48 4.2464e-09 1460820000.0 61309.0 114916.0 129852.0 131220.0 119935.0 113483.0 83971.0 102073.0 115836.0 100209.0 True False 60434.72241730636 114649.91906241777 119176.06980321533 140870.35653708788 112880.65910128246 108629.59663179365 88318.6075067415 106815.68421580696 102789.32987284343 117529.9921299007 0.5142068107220712 0.975494994806945 1.0140055967288357 1.1985907085009426 0.9604413057096138 0.9242712831268649 0.7514559127097264 0.9088376701135853 0.8745795690961583 1.0 16.842669435275567 -10.059573416294015 15.046913866083315 1.0000041966824686 0.9146690890070807 0.02470547107753418 0.16882418928264595 0.0 0.0 0.16871369579873202 0.040919081662735224 8.718195101263421e-11 10.059573416294015 -0.08533510767538799 RFS(ph)FFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RFSFFK 6 1 A4QPE4;O15020 A4QPE4 SPTBN2 Spectrin beta chain, non-erythrocytic 2 1 RFS(1)FFK 64.567 0.036834 1324300.0 22317.0 24773.0 18591.0 15158.0 23044.0 9899.6 9444.2 12616.0 7048.3 7138.6 True False 26094.827319158136 27232.299720946634 19034.279946760133 14308.746402899047 18528.693622738127 9380.447548750206 8549.577005913141 12284.843367756936 7151.368053426445 8432.771670873492 3.094454390279389 3.229341524211556 2.257179571516669 1.6968023043148404 2.1972246309876513 1.112380118288979 1.0138513574893877 1.4567978177552665 0.8480447867605652 1.0 13.041791176637599 -5.4138253152390865 0.5212757522307384 0.9885646788718522 4.065421418373746 0.8742883652341821 0.29345043626642137 0.7844161692971943 0.25998107445706287 0.19834678212850176 1.3672998323234271 3.8563343847331486e-06 5.4138253152390865 3.0768567395018938 up RFS(ph)FSQR ddPTM_PC-9_AZD4547_30min_R2 3 RFSFSQR 7 1 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 RFS(0.932)FS(0.068)QR;RFS(0.986)FS(0.014)QR;RFS(0.996)FS(0.004)QR 75.509 0.014952000000000002 275695000.0 54489.0 70673.0 88209.0 117758.0 117779.0 83481.0 60413.0 100391.0 80479.0 81556.0 True False 71815.36855839232 93516.66516415986 87039.29102526334 90610.71244296385 101427.41886352569 78260.9198730751 65789.63996451134 84877.87770568117 84732.95563886507 78700.74926371439 0.9125118786067692 1.1882563512934237 1.1059525079438286 1.1513322718102843 1.2887732304003567 0.9944113697168817 0.8359468058437429 1.0784888136359179 1.0766473817795261 1.0 16.264089750401645 -6.932517199014182 24.999855287548993 0.9915752969671218 1.1334608853871808 0.27258857970101147 0.1077503832098747 70.3460557788513 26059.637550331485 0.038490465608611676 0.033945397024514615 1.1681074693270945e-07 6.932517199014182 0.14188558842005905 RFS(ph)FSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 RFSFSQR 7 1 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 RFS(0.91)FS(0.09)QR;RFS(0.915)FS(0.085)QR;RFS(0.919)FS(0.081)QR;RFS(0.945)FS(0.055)QR;RFS(0.986)FS(0.014)QR;RFS(0.928)FS(0.072)QR 77.533 0.013594 296817000.0 121566.0 99012.3 120983.9 119651.7 140140.0 110226.1 110420.0 109063.0 95685.9 82193.0 True False 142144.72276205465 108841.5867945055 123868.61500999593 112948.00316504524 112680.5730034073 104445.64927404081 99960.21822842897 106200.21181180025 97085.12526756218 97093.9402605699 1.4639917010328602 1.120992582054128 1.2757605127320113 1.1632858122960916 1.160531467782724 1.0757174854964298 1.0295206679239393 1.0937882583278828 0.9999092117079185 1.0 16.567093637821834 -1.5228787452803525 0.2635720371101135 0.9988407370619817 3.602476531235686 0.7437396058292185 0.06836771467406323 25.902000642943705 0.35906077739896547 0.07875544175648258 30.42936634880893 0.02999999999999897 1.5228787452803525 2.6036357941737043 RFS(ph)FSQR ddPTM_PC-9_Lapatinib_30min_R1 6 RFSFSQR 7 1 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 RFS(0.938)FS(0.062)QR;RFS(0.988)FS(0.012)QR;RFS(0.919)FS(0.081)QR;RFS(0.953)FS(0.047)QR;RFS(0.922)FS(0.078)QR;RFS(0.919)FS(0.081)QR 89.88600000000001 0.007471800000000001 287633000.0 142277.0 99807.0 138276.7 114434.0 115734.0 107063.5 101063.4 88693.5 129479.0 90840.0 True False 140248.10388959348 99575.90302362389 126908.12348949749 122849.85810063356 108926.75366179856 102484.64368220819 106295.96834498597 92814.52380154071 114895.71154568448 106541.57296330863 1.3163697511570707 0.934620169892896 1.1911605954344489 1.1530696861678704 1.0223873238600611 0.9619216314508742 0.9976947532170636 0.8711578139878288 1.078412007163184 1.0 16.701056960332245 -6.402434316931887 3.6036026475904097 0.975774311103557 1.136331808092692 0.38375385503991266 0.09969705051009521 0.264727539633692 6.226218584572012 0.03076667712066471 0.034961677231730756 3.958819338298465e-07 6.402434316931887 0.16055749698913513 RFS(ph)ITR ddPTM_PC-9_AZD4547_30min_R2 1 RFSITR 6 1 O14924-5;O14924-4;O14924;E9PBG5;O14924-6 O14924-5 RGS12 Regulator of G-protein signaling 12 1 RFS(0.966)IT(0.034)R 60.91 0.042137 1253400.0 626.07 0.0 2208.9 2408.6 1101.2 819.13 634.68 1293.6 2224.1 2136.4 True False 825.1472369350258 0.0 2179.6085427303806 1853.3344824990456 948.317388095624 767.9096716094904 691.165290461922 1093.7038439707687 2341.6613854098587 2061.605286269551 0.4002450141307696 0.0 1.0572385302107732 0.8989763922523847 0.45998979262009576 0.3724814234440645 0.33525587806023577 0.5305107875183092 1.1358437044207748 1.0 11.009552426266538 -8.255404514534872 23.09395926553732 1.067921927955787 0.5096011277377894 0.39098586826765447 0.28008842264049183 171.61261492503817 656739.1151860597 0.21705857501511644 0.07685651962725792 5.553867129126658e-09 8.255404514534872 -0.5583208002179976 RFS(ph)LDER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RFSLDER 7 1 Q7LBC6;Q7LBC6-2 Q7LBC6 KDM3B Lysine-specific demethylase 3B 1 RFS(1)LDER 57.174 0.040451 4506500.0 11066.0 11086.0 15447.0 13581.0 15838.0 16228.0 19416.0 17084.0 12540.0 15739.0 True False 12939.255236537343 12186.544815178395 15815.315063073731 12820.10060019608 12734.657594034305 15376.975112238715 17576.775920333057 16635.563101994256 12723.37377665077 18592.356110144563 0.6959448904637366 0.6554599504755096 0.8506353347247048 0.6895360934486963 0.6849404948244232 0.8270589817203728 0.945376466339445 0.8947528222588949 0.6843335885605432 1.0 14.182421986441286 -6.904518376373367 4.83458115874262 0.8741390337696858 0.7187189017366856 0.43171475320820085 0.09028231599432057 0.219104507848521 8.674790660578932 0.03237970801849996 0.028412083757641416 1.2458955183747835e-07 6.904518376373367 -0.1554201320330002 RFS(ph)LDER ddPTM_PC-9_Lapatinib_30min_R1 1 RFSLDER 7 1 Q7LBC6;Q7LBC6-2 Q7LBC6 KDM3B Lysine-specific demethylase 3B 1 RFS(1)LDER 60.434 0.034412 8008000.0 25739.0 21980.0 27598.0 19208.0 31483.0 29993.0 34155.0 30930.0 35456.0 30490.0 True False 25371.957140045502 21929.106660447174 25328.99897136074 20620.620396009628 29631.231837959498 28710.26930709786 35923.378778301485 32367.12071551637 31462.57191176786 35760.15587462878 0.7095035387708272 0.61322737902285 0.7083022529365213 0.576636759311209 0.828610253877063 0.8028563803735349 1.0045643789765613 0.9051168800547732 0.8798220013937361 1.0 15.126065404635105 -6.670600043978697 1.6444166146497385 0.9352130142363854 0.6537385187834373 0.7940903906905851 0.06439505628750436 0.15503762764641393 0.8665205885753031 0.025302088694001704 0.024732628803219314 2.1350102089260625e-07 6.670600043978697 -0.2814744954529481 RFS(ph)LDTDYR ddPTM_PC-9_AZD4547_30min_R2 2 RFSLDTDYR 9 1 E9PP00;Q9C0D7;Q9C0D7-2 E9PP00 ZC3H12C Probable ribonuclease ZC3H12C 1 RFS(0.999)LDT(0.001)DYR;RFS(0.995)LDT(0.005)DYR 80.17 0.0087462 7012400.0 31472.0 27809.0 38077.0 55200.0 47878.0 33148.0 30831.0 47713.0 39722.0 40829.0 True False 41479.44134173358 36797.71541536545 37572.07410093018 42474.492831498515 41230.96613443723 31075.25031986545 33574.899272438895 40340.05218566578 41821.62382592976 39399.5891373804 1.0527886774935915 0.933961907243687 0.953615885940385 1.0780440548097188 1.0464821343865058 0.7887201618146514 0.852163690219416 1.0238698694295043 1.061473602684132 1.0 15.265892964750025 -4.746519683482081 24.11897268668419 0.9674340577075897 1.052789030377535 0.07046994263787854 0.08837951837323496 1645.188448981009 2659352.189152765 0.02396617519192448 0.5115149840539152 1.7925873052827788e-05 4.746519683482081 0.08535497266994518 RFS(ph)LDTDYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RFSLDTDYR 9 1 E9PP00;Q9C0D7;Q9C0D7-2 E9PP00 ZC3H12C Probable ribonuclease ZC3H12C 1 RFS(1)LDTDYR 62.14 0.028839999999999998 1546500.0 11176.0 11188.0 12441.0 13134.0 13691.0 10666.0 11984.0 12144.0 10201.0 7645.0 True False 13067.876063938313 12298.670701083878 12737.640622755242 12398.144561002518 11008.346831665845 10106.656183580117 10848.788763353485 11825.232867631596 10350.170326604026 9030.977982213297 1.4470056387775247 1.3618315452995646 1.4104386753951006 1.372846283693851 1.2189540106671746 1.119109824371778 1.2012861491546547 1.3094077840652079 1.1460741402524628 1.0 13.140666513086964 -1.5228787452880759 0.10052605638470959 0.8734856466204425 2.566056214382303 0.7667475279646778 0.0663422342814261 69.15068329244548 0.49416865798949855 0.9414816957866916 16.14368573340666 0.029999999999465458 1.5228787452880759 1.6925705677618605 RFS(ph)LDTDYR ddPTM_PC-9_Lapatinib_30min_R1 2 RFSLDTDYR 9 1 E9PP00;Q9C0D7;Q9C0D7-2 E9PP00 ZC3H12C Probable ribonuclease ZC3H12C 1 RFS(0.947)LDT(0.053)DYR;RFS(1)LDTDYR 87.641 0.0049207 9229000.0 49777.0 38949.0 48479.0 36826.0 43310.0 39162.0 37095.0 30033.0 41085.0 43944.0 True False 49067.1708520162 38858.815983519446 44493.243754351715 39534.30688793475 40762.590950736165 37487.13255108082 39015.59759277103 31428.442820856853 36457.57465577005 51539.66184830062 0.9520274113640514 0.7539594671360986 0.863281639008634 0.7670657018336314 0.7908975241381061 0.7273453338017362 0.7570014275143613 0.6097914051776636 0.7073693025592123 1.0 15.653395451256486 -1.5228787452864816 0.6053937290128223 0.745614736702757 12.422891964481938 0.17829543468390507 0.10003509543492703 266.09667037289876 2.023063610193856 0.04309875521414446 4116.78813731526 0.029999999999575585 1.5228787452864816 11.67727722777918 RFS(ph)LSVPR ddPTM_PC-9_AZD4547_30min_R2 2 RFSLSVPR 8 1 Q07002;Q07002-3;A0A0A0MSJ6;D6R9B0;D6R9X1 Q07002 CDK18 Cyclin-dependent kinase 18 1 RFS(0.971)LS(0.029)VPR;RFS(0.971)LS(0.029)VPR 73.9 0.013152 45900000.0 26314.0 27890.0 34750.0 52685.0 51156.0 36741.0 33694.0 48673.0 44503.0 48069.0 True False 34681.30463479846 36904.897081324096 34289.19229475334 40539.28722513587 44053.87241683594 34443.57946187334 36692.70072607299 41151.70624427116 46855.33772532483 46386.11894106487 0.747665582431292 0.7956021741808796 0.7392123565741491 0.8739529874582179 0.9497210247920908 0.7425406619086858 0.7910276083388719 0.8871556229258108 1.0101154999592898 1.0 15.501405522596212 -8.08135054766228 2.8886651660300906 1.0062812820902014 0.8088396374970694 0.6220353147571567 0.06167197249344282 0.19745191474517956 3.0260820964807804 0.05346306355579088 0.017758515650650935 8.291812105959795e-09 8.08135054766228 -0.19744164459313196 RFS(ph)LSVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RFSLSVPR 8 1 Q07002;Q07002-3;A0A0A0MSJ6;D6R9B0;D6R9X1 Q07002 CDK18 Cyclin-dependent kinase 18 1 RFS(0.911)LS(0.089)VPR;RFS(0.973)LS(0.027)VPR;RFS(0.962)LS(0.038)VPR;RFS(0.979)LS(0.021)VPR 76.143 0.011632 58759000.0 86509.0 85703.0 88454.0 88200.0 92993.0 91294.0 78175.0 75350.0 62465.0 62765.0 True False 101153.26506936617 94211.02744860497 90563.07882366303 83258.4399482583 74771.68920583605 86506.38192609805 70769.69806201277 73372.14233992422 63378.43245283014 74143.79765253328 1.3642849202762688 1.2706528453008916 1.2214518502016434 1.1229319590350602 1.0084685647779377 1.1667379425518594 0.95449249030468 0.9895924495771671 0.8548042379734332 1.0 16.17803839157947 -5.227348639690338 0.4166170512331564 0.9322463941302148 1.5678761065250888 0.8231741845991448 0.06382059351263614 1.5201869868667772 0.2731311599684599 0.05304217241545126 0.4639594326877759 5.924495314053776e-06 5.227348639690338 0.635629712394874 RFS(ph)LSVPR ddPTM_PC-9_Lapatinib_30min_R1 1 RFSLSVPR 8 1 Q07002;Q07002-3;A0A0A0MSJ6;D6R9B0;D6R9X1 Q07002 CDK18 Cyclin-dependent kinase 18 1 RFS(0.995)LS(0.005)VPR 62.408 0.028452999999999996 13220000.0 20687.0 14489.0 15167.0 16484.0 16941.0 13085.0 13717.0 10805.0 13778.0 12542.0 True False 20391.999586468824 14455.451610701499 13920.027806313083 17696.28834901202 15944.563687287491 12525.385052624802 14427.19914220353 11307.0397455918 12226.176551227923 14709.867988835482 1.3862802577117603 0.9827043738035528 0.9463054200675443 1.2030215609306063 1.0839365587365652 0.8514954085333287 0.9807837264857514 0.7686703751640486 0.8311547432313713 1.0 13.844496678983322 -6.722786310252449 6.139474947128841 0.8776743605785837 1.1094027544398075 0.44646653330095165 0.12993047259750837 0.18445423292708568 18.186352513266662 0.04374998776750067 0.04290909254743351 1.893274954287682e-07 6.722786310252449 0.2317283938612238 RFS(ph)MEDVSK ddPTM_PC-9_AZD4547_30min_R2 2 RFSMEDVSK 9 1 Q07002 Q07002 CDK18 Cyclin-dependent kinase 18 1 RFS(1)MEDVSK;RFS(1)MEDVSK 69.86399999999999 0.024447 18199500.0 166028.0 181273.0 199044.0 251903.0 227104.0 213083.0 172551.0 200365.0 195557.0 210410.0 True False 218821.45040306737 239865.95226327964 196404.54650696082 193830.65521255368 195574.52970038896 199758.88632520483 187907.70472442047 169403.19317965562 205893.74378247166 203043.60994381938 1.0777066585036268 1.1813518895258448 0.9673022783691861 0.9546257341769344 0.9632144038145448 0.983822570828388 0.9254549048670535 0.8343192540091667 1.0140370526284521 1.0 17.631430098855283 -5.3288489306634155 6.188806812578548 0.9487501340511462 1.1289510684766613 0.6362984835554918 0.05254392639533152 0.12040998073907745 8.691662828084276 0.013709100225963222 0.029220045978435298 4.6897648724779324e-06 5.3288489306634155 0.1802009344255151 RFS(ph)MEDVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RFSMEDVSK 9 1 Q07002 Q07002 CDK18 Cyclin-dependent kinase 18 1 RFS(1)MEDVSK 52.101000000000006 0.039797000000000006 11708000.0 147600.0 133370.0 115360.0 130480.0 171980.0 125860.0 129520.0 134040.0 107990.0 105750.0 True False 172585.76476711634 146610.09218837676 118110.61990523635 123169.62862186776 138281.7535687599 119259.68003613278 117250.92795640406 130521.59202711922 109569.14945299165 124921.63788346044 1.3815522089785746 1.1736164740743273 0.945477676296735 0.9859751337616376 1.106947970837231 0.9546759236969843 0.9385958264955476 1.0448277355191498 0.877103048834573 1.0 16.930663864620833 -4.942039631492614 2.4966809189338806 0.9853905763395044 1.4068012216309427 0.813972863640839 0.0604694845866978 0.1493631194577164 1.5232722396623646 0.015901309480434674 0.11707813444070772 1.1427740463182715e-05 4.942039631492614 0.42141064529143824 RFS(ph)PPSSSLQPGK ddPTM_PC-9_AZD4547_30min_R2 2 RFSPPSSSLQPGK 13 1 I3L0L0;I3L354;A0A2R8Y7Z3;A0A0D9SEN7;Q13950-3;Q13950-2;Q13950 I3L0L0 RUNX2 Runt-related transcription factor 2 1 RFS(0.935)PPS(0.05)S(0.007)S(0.008)LQPGK;RFS(1)PPSSSLQPGK 156.2 0.00029667 36769600.0 114085.0 95571.0 152995.0 188518.0 156104.0 142927.0 113356.0 141814.0 124434.0 137937.0 True False 150361.65688458527 126462.45675723287 150966.18633484282 145058.0876740659 134431.65415118 133989.75209567434 123444.46440033056 119899.90486152629 131011.32720295411 133107.86761475552 1.1296226104362677 0.9500749957413788 1.1341642612123675 1.0897784651910811 1.0099452163132523 1.0066253370046554 0.9274017127042178 0.9007724863307398 0.9842493126111127 1.0 17.022236321669602 -6.767421343468499 1.8244853944739585 0.9469464694672562 1.0690932427508515 0.47233922621516755 0.05584475380141179 0.2973713291582693 2.0444749117613576 0.02280600405807659 0.020767440653235134 1.708357098331459e-07 6.767421343468499 0.12214677328359524 RFS(ph)PPSSSLQPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RFSPPSSSLQPGK 13 1 I3L0L0;I3L354;A0A2R8Y7Z3;A0A0D9SEN7;Q13950-3;Q13950-2;Q13950 I3L0L0 RUNX2 Runt-related transcription factor 2 1 RFS(1)PPSSSLQPGK;RFS(0.993)PPS(0.001)S(0.003)S(0.003)LQPGK;RFS(0.976)PPS(0.019)S(0.003)S(0.003)LQPGK 73.279 0.009923999999999999 28908200.0 135727.0 140278.0 142557.0 167375.0 165500.0 143982.0 146469.0 169348.0 139726.0 122487.0 True False 158702.90036955534 154203.87277499482 145956.09953043316 157997.52138707114 133071.46305169066 136431.33045417513 132594.3959762704 164902.79443903745 141769.22841437816 144692.92349344183 1.0968255844021875 1.0657319587711838 1.0087300470990108 1.0919505776260878 0.9196819017740151 0.9429025771281678 0.9163848015157439 1.1396742180450283 0.979793793583857 1.0 17.142634840048217 -6.244489199047195 24.964323297978616 0.9847136696657539 1.0617268939978897 0.29068429429803366 0.06315606177112139 1223.9627574911774 1802659.0424347834 0.019731235750858337 0.025411256369221508 5.695223880379007e-07 6.244489199047195 0.07701322433213575 RFS(ph)PPSSSLQPGK ddPTM_PC-9_Lapatinib_30min_R1 1 RFSPPSSSLQPGK 13 1 I3L0L0;I3L354;A0A2R8Y7Z3;A0A0D9SEN7;Q13950-3;Q13950-2;Q13950 I3L0L0 RUNX2 Runt-related transcription factor 2 1 RFS(0.993)PPS(0.005)S(0.002)S(0.001)LQPGK 60.158 0.026836000000000002 18396000.0 52175.0 47899.0 45704.0 46253.0 45950.0 48922.0 41017.0 45484.0 48769.0 46044.0 True False 51430.97493227682 47788.092808405774 41946.39354254192 49654.59991548484 43247.311341175824 46829.72010275205 43140.65956227763 47597.35268750552 43276.12165966284 54002.64405022652 0.9523788295336455 0.8849213524426555 0.7767470330439491 0.9194846065185684 0.8008369238541834 0.8671745786964966 0.7988619876121913 0.8813893009245326 0.8013704221484561 1.0 15.720742425061943 -4.872031308277627 3.938325390202633 0.8491763541204574 0.953334034168133 0.16282064010734099 0.064515335167214 0.33936552727381086 8.760430442766348 0.014593619090736783 0.08256488570659758 1.3426681647366647e-05 4.872031308277627 0.10415768004767556 RFS(ph)PSQVPIQTR ddPTM_PC-9_AZD4547_30min_R2 2 RFSPSQVPIQTR 12 1 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 RFS(0.969)PS(0.031)QVPIQTR;RFS(0.989)PS(0.011)QVPIQTR 90.853 0.0041566 17663000.0 25049.3 19150.0 39840.0 69347.0 52499.0 35880.0 38351.5 47413.0 34712.0 39014.0 True False 33014.45634219264 25339.863001339443 39311.695569006435 53360.12055046974 45210.42004870338 33636.41792798279 41764.709203299935 40086.41029235159 36546.805454047484 37648.131734937415 0.8769215050200027 0.6730709289838169 1.0441871550434796 1.417337809115017 1.2008675587678146 0.893441888824678 1.1093434728008653 1.0647649284320648 0.9707468543553809 1.0 15.20029065338113 -5.363487382151866 5.783568332520177 1.1024476064787578 0.7776564252265898 0.43490769631849313 0.14274462944674135 0.19908512257757802 9.224794362748222 0.03980594835761062 0.08469042566723592 4.330246485100595e-06 5.363487382151866 -0.324791181252168 RFS(ph)PSQVPIQTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RFSPSQVPIQTR 12 1 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 RFS(0.958)PS(0.042)QVPIQTR;RFS(0.969)PS(0.031)QVPIQTR 89.23200000000001 0.0034857 13307500.0 53274.0 47950.0 56466.0 48934.0 66065.0 60933.0 62615.0 55447.0 65864.0 56466.0 True False 62292.235990537694 52710.15910948982 57812.36358849754 46192.3866261685 53120.03750157067 57737.56621358402 56683.65390665714 53991.57500095263 66827.13639755399 66702.8388153899 0.9338768348816576 0.7902236253448385 0.8667151895663978 0.6925100557415983 0.7963684671440796 0.8655938373684722 0.8497937256244468 0.8094344402699621 1.001863452656162 1.0 16.025460542124712 -8.263824363093983 24.782244674749233 1.0009317608769657 0.8224917785011675 0.5787732622481521 0.05979687768440505 132.91069793121966 1381016.2498888418 0.04977722070989816 0.015174982842086484 5.4472290455205565e-09 8.263824363093983 -0.17843998237579817 RFS(ph)PSQVPIQTR ddPTM_PC-9_Lapatinib_30min_R1 2 RFSPSQVPIQTR 12 1 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 RFS(0.998)PS(0.002)QVPIQTR;RFS(0.999)PS(0.001)QVPIQTR 116.87 0.00030104 24646000.0 43477.0 36198.0 45455.0 26408.0 50031.0 41618.0 40286.0 42263.0 47691.0 39496.0 True False 42857.010007294695 36114.185754998485 41717.86536137411 28350.13241450553 47088.27494473054 39838.09515629645 42371.81195908808 44226.69326866692 42319.537371506114 46322.830974888064 0.9251811494536633 0.7796195740838086 0.9005897196565914 0.612012086002998 1.016524118965385 0.8600099414885278 0.9147068749329708 0.9547493609067745 0.9135783906309145 1.0 15.49943580447909 RFS(ph)SEDLEDPLR ddPTM_PC-9_Lapatinib_30min_R1 1 RFSSEDLEDPLR 12 1 A0A0R4J2E4;K7ENL6;Q8TES7-4;Q8TES7-3;Q8TES7-2;Q8TES7-5;Q8TES7;Q8TES7-6 A0A0R4J2E4 FBF1 Fas-binding factor 1 1 RFS(0.916)S(0.084)EDLEDPLR 78.615 0.023918000000000002 1699500.0 3195.2 5315.8 6239.3 3053.4 6061.9 3825.5 1561.1 4555.5 5518.4 3466.9 True False 3149.6358620720825 5303.491591701779 5726.328838394493 3277.9572218438043 5705.350960153948 3661.8922826760563 1641.9261194790356 4767.165160670376 4896.859680671807 4066.149045646127 0.7745992157972146 1.3043032934025254 1.408292901738568 0.8061576654091694 1.4031337504125714 0.9005799447015025 0.40380372215749094 1.1724029560044953 1.2042991109524557 1.0 11.989447383138767 RFS(ph)SGGEEDDFDR ddPTM_PC-9_AZD4547_30min_R2 3 RFSSGGEEDDFDR 13 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 RFS(0.959)S(0.041)GGEEDDFDR;RFS(0.917)S(0.083)GGEEDDFDR;RFS(0.968)S(0.032)GGEEDDFDR 137.73 8.953200000000001e-05 182150000.0 196227.0 208645.2 268114.8 325156.0 303959.0 266973.0 186852.0 279833.0 203607.0 290627.0 True False 258623.10422484583 276085.6806207344 264559.4225689019 250196.30781012183 261759.53956425536 250279.13610611294 203481.4660197126 236591.23977262777 214369.250348071 280452.2371899745 0.9221645254684064 0.9844303022397276 0.9433314749765856 0.8921173541598182 0.9333480174270923 0.8924126924920098 0.7255476656507361 0.8436061774481909 0.7643699066050245 1.0 18.097395565996386 -7.023740320569392 10.428696591817582 0.818684753091113 0.9336315649426952 0.30814764663540384 0.07046328345977551 0.6006045644012192 259.7339170427129 0.024881665565167587 0.019804516018655023 9.468031179087365e-08 7.023740320569392 0.11494681185158218 RFS(ph)SGGEEDDFDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RFSSGGEEDDFDR 13 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 RFS(0.922)S(0.078)GGEEDDFDR;RFS(0.935)S(0.065)GGEEDDFDR;RFS(0.739)S(0.261)GGEEDDFDR 172.43 0.00030564 125001700.0 49626.9 52176.1 74286.0 58917.7 75345.8 56677.7 58187.4 57429.8 53557.2 42169.4 True False 58027.75399404618 57355.7983881679 76057.25997122392 55616.73228276065 60582.33136435091 53705.42163661153 52675.468231705185 55922.328601902926 54340.37272973212 49814.37840721328 1.1648796160757389 1.1513904262601942 1.5268133900916163 1.116479499716234 1.216161544145222 1.0781108457801176 1.0574350200880478 1.1226142007586548 1.0908571875678261 1.0 15.604274601014954 -6.534346271475184 1.694225547284429 1.0744791006558019 1.2585577652227773 0.3617889443462613 0.109576559393385 0.42389945880908114 2.471710306605905 0.04316758007741481 0.046819218093359455 2.921821823245466e-07 6.534346271475184 0.18407866456697541 RFS(ph)SGGEEDDFDR ddPTM_PC-9_Lapatinib_30min_R1 6 RFSSGGEEDDFDR 13 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 RFS(0.678)S(0.322)GGEEDDFDR;RFS(0.947)S(0.053)GGEEDDFDR;RFS(0.5)S(0.5)GGEEDDFDR;RFS(0.998)S(0.002)GGEEDDFDR;RFS(0.916)S(0.084)GGEEDDFDR;RFS(0.992)S(0.008)GGEEDDFDR 220.27 1.0625e-14 128911700.0 235692.0 217910.0 251674.0 203355.0 226093.0 188837.0 154394.8 156497.4 197229.0 146229.0 True False 232330.98885938054 217405.44278334995 230982.3352097347 218310.40507239333 212794.65425594084 180760.8817105474 162388.60728444165 163768.8405258473 175014.99310655642 171504.4878121055 1.3546641946414515 1.267637048784006 1.3468005307405782 1.2729136587467424 1.2407526879942141 1.0539717299327052 0.9468475685741186 0.954895365217888 1.020468882996793 1.0 17.387886802785673 -6.75791398207534 2.1298842337426667 0.9754949291434791 1.30983337194434 0.9569456967341461 0.03250916778201673 0.05638065830969914 0.5260295307840749 0.012572241238106654 0.01160072552277344 1.7461679709713002e-07 6.75791398207534 0.3343384428008609 RFS(ph)VQR ddPTM_PC-9_Lapatinib_30min_R1 1 RFSVQR 6 1 H0YM35;H0YL54;H7C0H1;Q9NQ69-3;Q9NQ69-4;Q9NQ69-2;Q9NQ69;P50458 H0YM35 LHX2;LHX9 LIM/homeobox protein Lhx9;LIM/homeobox protein Lhx2 1 RFS(1)VQR 86.935 0.016666999999999998 0.0 63684.0 63849.0 66072.0 53258.0 70893.0 60884.0 57277.0 59036.0 67912.0 50236.0 True False 62775.85448178475 63701.16156337087 60639.815205295636 57174.770983479866 66723.21312100069 58280.133247536025 60242.52280148663 61779.02808151387 60263.03541493626 58919.22566473765 1.0654562033620758 1.081160874819425 1.0292025144788646 0.9703924370767517 1.1324523085328602 0.9891530750787835 1.022459513373085 1.04853767822831 1.0228076614218449 1.0 15.84645084968927 -5.2685652796894225 22.73168121932463 1.0288575149869565 1.073308540873446 0.16620850210222593 0.041409572754889316 257.51011241742634 821472.9124737467 0.010468179962022841 0.022646505426778856 5.388088498288892e-06 5.2685652796894225 0.044451025886489415 RFSDGAAS(ph)IQAFK ddPTM_PC-9_Lapatinib_30min_R1 1 RFSDGAASIQAFK 13 1 H0Y4E8;Q9Y2K2-7;Q9Y2K2;Q9Y2K2-8 H0Y4E8 SIK3 Serine/threonine-protein kinase SIK3 1 RFS(0.01)DGAAS(0.99)IQAFK 192.39 7.9938e-06 11367000.0 69899.0 47387.0 61885.0 56513.0 51054.0 38016.0 33685.0 28594.0 44521.0 49783.0 True False 68902.22744209325 47277.27831294861 56797.05418300822 60669.154541841504 48051.104096025905 36390.14429962436 35429.044478029144 29922.581627529078 39506.57615308595 58387.925218322176 1.1800766542817946 0.8097098524424527 0.9727534241135403 1.0390702241086567 0.8229630341608274 0.6232477719246838 0.6067871798073667 0.5124789331979782 0.6766223667884119 1.0 15.833382426243826 -6.540218798956893 3.341424775521838 0.6493136466828872 0.9833136906376058 0.4955469492595531 0.14772516311984693 0.18820098315301012 4.4106793192256015 0.04815987256040649 0.05058009056714048 2.882578884726467e-07 6.540218798956893 0.3340000439547186 RFSDS(ph)EGEETVPEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RFSDSEGEETVPEPR 15 1 A0A1B0GV41;A0A1B0GWH8;H3BR84;A0A1B0GWD3;A0A1B0GV71;A0A1B0GW34;A0A0D9SFH9;H3BPL0;Q9UBD8;H3BQ48;O95090;H3BR00;Q9UP10;Q9UBH5;A0A0D9SF04;Q13286-5;Q13286-4;Q13286-6;Q13286-2;Q13286-7;Q13286-3;Q13286 A0A1B0GV41 CLN3 Battenin 1 RFS(0.033)DS(0.734)EGEET(0.233)VPEPR 187.0 5.0012e-07 8266400.0 10445.0 17406.0 14614.0 10431.0 18636.0 12405.0 14543.0 12776.0 10504.0 8162.7 True False 12213.132201846429 19133.952647753482 14962.453183903624 9846.584887758281 14984.409579645366 11754.459962245573 13165.381757797877 12440.643537290947 10657.60112838434 9642.532894102356 1.2665896332400715 1.9843284806895856 1.5517139892833636 1.0211616590678916 1.5539910254089204 1.2190220237086182 1.3653447597622606 1.2901841947461745 1.1052698751904522 1.0 13.235196447069393 -5.508316030670266 0.1739596827035089 0.9126720266666056 2.0720201139181524 0.32686474570925483 0.23221717557468452 16.32457216830641 0.6787482008064625 0.8485304768475346 4.395003977107848 3.1023012606691406e-06 5.508316030670266 1.159348087251547 RFSDS(ph)EGEETVPEPR ddPTM_PC-9_Lapatinib_30min_R1 1 RFSDSEGEETVPEPR 15 1 A0A1B0GV41;A0A1B0GWH8;H3BR84;A0A1B0GWD3;A0A1B0GV71;A0A1B0GW34;A0A0D9SFH9;H3BPL0;Q9UBD8;H3BQ48;O95090;H3BR00;Q9UP10;Q9UBH5;A0A0D9SF04;Q13286-5;Q13286-4;Q13286-6;Q13286-2;Q13286-7;Q13286-3;Q13286 A0A1B0GV41 CLN3 Battenin 1 RFS(0.175)DS(0.825)EGEETVPEPR 213.94 5.371499999999999e-64 0.0 9739.3 12358.0 11439.0 6647.2 8559.2 9462.5 9766.7 5711.8 9337.0 8205.3 True False 9600.415796031122 12329.38581027325 10498.529575816929 7136.05726240916 8055.764684034651 9057.810933164857 10272.371937169879 5977.191079951065 8285.368737031145 9623.575172124998 0.9975934748074751 1.2811648051532576 1.0909178125636994 0.741518316714456 0.8370864818896451 0.9412105970139979 1.0674174361856852 0.6210988092309182 0.8609449803052392 1.0 13.232357241536393 -5.632077761218227 6.109398586724243 0.8622535837087537 1.150021716709092 0.4327775685611136 0.13474826861296552 0.1804732172253507 8.9994901772406 0.03681521986314943 0.0643995272854915 2.3330402897661996e-06 5.632077761218227 0.2877681330003383 RFSEGTSADR ddPTM_PC-9_AZD4547_30min_R2 2 RFSEGTSADR 10 1 P62333;A0A087X2I1;H0YJX2 P62333 PSMC6 26S protease regulatory subunit 10B 0 ; 132.03 0.00010133 2908000.0 8651.9 8615.1 15171.099999999999 22216.4 19345.5 15392.6 11275.5 14437.3 10077.8 15225.5 False True 11403.024229300481 11399.762597537301 14969.92130137936 17094.752219958405 16659.711252637033 14430.098288691956 12278.997656462163 12206.347021149631 10610.491933763526 14692.45987928152 0.7761140287597712 0.7758920351800725 1.018884613221854 1.1635051148966868 1.1338953034086294 0.9821431133557471 0.8357346392197617 0.8307898827998391 0.7221725987985065 1.0 13.84278833831234 -7.262379756845938 7.830737815329775 0.8328349443960654 0.9839135675411967 0.17215246599206446 0.13513746629576548 0.21639958092939643 134.11227112367655 0.06094511831900466 0.04388557739672145 5.465378489214459e-08 7.262379756845938 0.15107862314513132 RFSEGTSADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RFSEGTSADR 10 1 P62333;A0A087X2I1;H0YJX2 P62333 PSMC6 26S protease regulatory subunit 10B 0 ; 116.84 0.0017800999999999997 685660.0 5902.9 4104.5 5883.5 7533.4 8095.1 7256.400000000001 6953.3 6604.4 7051.9 4713.3 False True 6902.144382410647 4511.967634304502 6023.784953298003 7111.328021612331 6508.923266161576 6875.861609837868 6294.633086467441 6431.0414979402285 7155.020696615912 5567.783979537731 1.2396573587942437 0.8103704545446663 1.081899904061675 1.2772277171218043 1.1690330102752986 1.2349368501198104 1.1305454934316717 1.1550450810547017 1.285075125563683 1.0 12.4428875228431 -5.5282689680095025 23.756028321016267 1.184779963682896 1.0052942382862597 0.2052679331641022 0.12339364494371834 87.78689929814126 386896.9385811792 0.030923718922499083 0.053827254451595176 2.9629957734985946e-06 5.5282689680095025 -0.1794857253966362 RFSEGTSADR ddPTM_PC-9_Lapatinib_30min_R1 1 RFSEGTSADR 10 1 P62333;A0A087X2I1;H0YJX2 P62333 PSMC6 26S protease regulatory subunit 10B 0 152.69 0.00010828 1285000.0 6824.7 4927.8 7909.8 4987.2 4239.0 6375.7 4766.3 5416.2 6333.4 4182.9 False True 6727.378526503301 4916.389981863128 7259.486776710972 5353.975324811498 3989.6703541946567 6103.02617348261 5013.075692314989 5667.856424810206 5620.065798341339 4905.9086916360975 1.3712808267248349 1.0021364625568552 1.4797435568027189 1.091332036802742 0.8132377924188638 1.2440154428245747 1.0218444751859317 1.1553122532576126 1.1455708109534901 1.0 12.260304667487553 -5.966525919650789 24.99966174640367 1.0666219031441357 1.2610580590146023 0.28701651181804055 0.1559574231478328 258.57934972796386 193114.96792266154 0.04234838035987453 0.06281247288927136 1.080125154711015e-06 5.966525919650789 0.1944361558704666 RFSFCCS(ph)PEPEAEAEAAAGPGPCER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RFSFCCSPEPEAEAEAAAGPGPCER 25 1 Q13501;E7EMC7;E3W990;D6RBF1;C9J6J8 Q13501 SQSTM1 Sequestosome-1 1 RFS(0.312)FCCS(0.688)PEPEAEAEAAAGPGPCER;RFS(0.409)FCCS(0.591)PEPEAEAEAAAGPGPCER;RFS(0.39)FCCS(0.61)PEPEAEAEAAAGPGPCER 110.03 1.3719e-07 626298800.0 36393.7 39622.1 47603.8 43065.4 56976.0 45467.0 46181.4 53274.0 51253.0 34568.1 True False 42554.43460165996 43555.52023466352 48738.85513041682 40652.58525791063 45811.96180563821 43082.63047992097 41806.763467617886 51875.61394846883 52002.4781638502 40835.022889070984 1.0421062997138457 1.0666216681935703 1.1935552298529801 0.995532324503504 1.1218791753854813 1.055041173772711 1.0237967438193105 1.2703706347707897 1.273477384967208 1.0 15.317519415921225 -7.757117263460592 24.999514332264134 1.2039430107914073 1.074162590876043 0.2351385879097193 0.08805762592051558 125.59868436908036 726487.7205543282 0.0410716319481805 0.022651397407844363 1.7493742778820456e-08 7.757117263460592 -0.12978041991536426 RFSFCCS(ph)PEPEAEAEAAAGPGPCER ddPTM_PC-9_Lapatinib_30min_R1 2 RFSFCCSPEPEAEAEAAAGPGPCER 25 1 Q13501;E7EMC7;E3W990;D6RBF1;C9J6J8 Q13501 SQSTM1 Sequestosome-1 1 RFS(0.193)FCCS(0.807)PEPEAEAEAAAGPGPCER;RFS(0.118)FCCS(0.882)PEPEAEAEAAAGPGPCER 103.71 3.6915e-07 505147800.0 39714.7 55248.1 52130.9 67475.8 70894.7 69831.5 55030.2 51572.4 76055.8 50199.7 True False 39148.36109521597 55120.17641888313 47844.898633093355 72438.1954246702 66724.81313034298 66844.96953017716 57879.39449116343 53968.641978302476 67489.59490092036 58876.65125810435 0.6649216668861957 0.9361975459040031 0.8126294143895882 1.2303382389585056 1.1332983738805684 1.1353391896753973 0.9830619312472592 0.9166391230661868 1.1462879334807692 1.0 15.845407996754217 -4.971515448605534 1.249948060364386 1.0664668437952307 0.6059373004216855 0.5327289325815509 0.11212720813774607 0.8690888933647104 1.4944941918948695 0.03556173142374376 0.4745031595761052 1.067786808840738e-05 4.971515448605534 -0.46052954337354524 RFT(ph)PPSTALSPGK ddPTM_PC-9_AZD4547_30min_R2 1 RFTPPSTALSPGK 13 1 C9JWM1;A8MZI9;H9KVB1;Q01196-6;Q01196-5;Q01196-7;Q01196-3;Q01196-4;Q01196;Q01196-9;Q01196-10;Q01196-2;Q01196-8 C9JWM1 RUNX1 Runt-related transcription factor 1 1 RFT(0.999)PPS(0.001)TALSPGK 105.95 0.00099512 9651300.0 52599.0 44488.0 65839.0 82032.0 62869.0 66875.0 46287.0 75686.0 54530.0 57402.0 True False 69324.3878728344 58867.87598974355 64965.93184156158 63120.78978176603 54140.724547932965 62693.295678200906 50406.45333019948 63990.46779125816 57412.344474798636 55392.37345180902 1.25151502910678 1.0627433403076363 1.1728317057596653 1.1395213067856838 0.9774039488492945 1.13180374429602 0.9099890506416509 1.1552216271600895 1.0364665909242357 1.0 15.757399735956339 -1.522878745294902 0.35537027119726544 1.0315361137093086 3.256626123016385 0.3537477148239695 0.07950136940556458 75.0785191599832 1.0523066349822487 0.06377524204879725 112.50991557629123 0.029999999998993925 1.522878745294902 2.2250900093070762 RFT(ph)PPSTALSPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RFTPPSTALSPGK 13 1 C9JWM1;A8MZI9;H9KVB1;Q01196-6;Q01196-5;Q01196-7;Q01196-3;Q01196-4;Q01196;Q01196-9;Q01196-10;Q01196-2;Q01196-8 C9JWM1 RUNX1 Runt-related transcription factor 1 1 RFT(0.994)PPS(0.005)T(0.001)ALSPGK 109.36 0.00067521 8643600.0 51823.0 57869.0 46950.0 66381.0 72190.0 54892.0 59160.0 53682.0 47910.0 46803.0 True False 60595.610349094066 63613.851877102534 48069.46605886654 62661.887780105644 58044.887720251114 52013.36688815668 53555.936518690956 52272.90438078057 48610.593113184856 55288.01340765585 1.0959990532179849 1.1505902989868286 0.8694373897002828 1.133372026194537 1.0498638699905523 0.9407711307086731 0.9686717466913894 0.9454654121021868 0.8792248105346762 1.0 15.754679113684276 -6.743825415339953 6.513503369850734 0.9445512925016114 1.0589105308293683 0.35039123447945775 0.07695050112247404 0.18848453828844758 30.519942791634943 0.02601014495258837 0.025068047006244803 1.8037426925477628e-07 6.743825415339953 0.11435923832775685 RFT(ph)PPSTALSPGK ddPTM_PC-9_Lapatinib_30min_R1 1 RFTPPSTALSPGK 13 1 C9JWM1;A8MZI9;H9KVB1;Q01196-6;Q01196-5;Q01196-7;Q01196-3;Q01196-4;Q01196;Q01196-9;Q01196-10;Q01196-2;Q01196-8 C9JWM1 RUNX1 Runt-related transcription factor 1 1 RFT(0.994)PPS(0.004)T(0.001)ALSPGK 118.21 0.00058209 0.0 53929.0 52731.0 60831.0 45075.0 51473.0 57446.0 41779.0 44432.0 52275.0 35303.0 True False 53159.962570632626 52608.904609283 55829.70999445054 48389.96586579204 48445.45933981162 54989.16849316653 43942.112193783 46496.47292699073 46387.239019846136 41405.07651170939 1.283899633794879 1.2705906869754282 1.3483783800921574 1.1686964484199738 1.170036706153923 1.3280779345406002 1.0612735416961767 1.1229655115802404 1.120327334903675 1.0 15.337520041217896 -7.4706662219343585 0.3339239734358671 0.9885096874376491 1.3277613134639659 0.638746344689308 0.06645970484262793 0.9596682280595363 0.3039376903994424 0.09364851918616163 0.115273761277276 3.383247566150664e-08 7.4706662219343585 0.33925162602631675 RFTDEESR ddPTM_PC-9_Lapatinib_30min_R1 2 RFTDEESR 8 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;H0YF00;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 0 ; 123.21 0.0011325999999999999 3052400.0 21257.5 18634.3 25507.0 22815.0 22788.8 22529.0 16342.5 20109.4 28251.0 16699.6 False True 20954.364151851925 18591.153423237978 23409.912919867347 24492.891208608893 21448.407588504633 21565.487187664043 17188.63468553337 21043.75613697396 25069.074883781406 19586.103609181722 1.0698587411754923 0.9492012190991718 1.1952307302659764 1.250523927440419 1.0950829228969199 1.101060610010988 0.8775933707138949 1.0744227926533028 1.279941911061337 1.0 14.257542801003083 RFTPPSTALS(ph)PGK ddPTM_PC-9_AZD4547_30min_R2 2 RFTPPSTALSPGK 13 1 C9JWM1;A8MZI9;H9KVB1;Q01196-6;Q01196-5;Q01196-7;Q01196-3;Q01196-4;Q01196;Q01196-9;Q01196-10;Q01196-2;Q01196-8 C9JWM1 RUNX1 Runt-related transcription factor 1 1 RFTPPSTALS(1)PGK;RFTPPSTALS(1)PGK 101.04 0.00096419 26248000.0 162895.0 173517.0 168544.0 185412.0 207932.0 196971.0 211784.0 212672.0 202082.0 194066.0 True False 214692.22157351638 229602.976940126 166308.99643530682 142668.1279868442 179064.2309675805 184654.37223223769 230632.36572002905 179808.42911638142 212763.6419614203 187271.80840909306 1.146420400365461 1.2260413293951913 0.888062105279652 0.7618238388299607 0.9561729151267487 0.9860233304783514 1.231538092568719 0.9601468082349695 1.1361221091892306 1.0 17.514774209417766 -9.173448282864477 15.321208104371147 1.0000134737013586 1.0260841531860017 0.0027792029376787486 0.14439776365587959 0.0 0.0 0.15087912675013948 0.03659356331128119 6.707361552908975e-10 9.173448282864477 0.026070679484643033 RFTPPSTALS(ph)PGK ddPTM_PC-9_Lapatinib_30min_R1 2 RFTPPSTALSPGK 13 1 C9JWM1;A8MZI9;H9KVB1;Q01196-6;Q01196-5;Q01196-7;Q01196-3;Q01196-4;Q01196;Q01196-9;Q01196-10;Q01196-2;Q01196-8 C9JWM1 RUNX1 Runt-related transcription factor 1 1 RFTPPSTALS(1)PGK;RFTPPSTALS(1)PGK 117.18 0.00012043 26853000.0 139470.0 131127.0 114385.0 147501.0 149234.0 125514.0 131450.0 123784.0 125104.0 117774.0 True False 137481.13222433452 130823.38348791885 104980.70683886898 158348.71558891138 140456.34952533277 120146.05880742449 138255.83781021036 129535.45653570886 111013.47011647685 138131.0789760097 0.9952947102383232 0.9470959356702047 0.7600078680128299 1.1463655881267172 1.0168337970466943 0.8697974394907259 1.000903191628745 0.9377719879984886 0.8036820601086987 1.0 17.075678431542215 -10.495268400139784 7.860050810419164 1.0000000004649923 0.9444715747923144 0.026040727552712473 0.105471108406588 8.67684473410781e-10 9.65492177673024e-11 0.10185538787677256 0.02470355997795531 3.196918757984194e-11 10.495268400139784 -0.055528425672677906 RFVEVGR ddPTM_PC-9_Lapatinib_30min_R1 1 RFVEVGR 7 1 E7EPB3;P50914 E7EPB3 RPL14 60S ribosomal protein L14 0 70.525 0.027691000000000004 2322900.0 9898.7 8313.8 10893.0 8020.0 9769.3 7393.7 7129.4 8061.9 9830.2 8637.5 False True 9757.542722800737 8294.549906898344 9997.419588195982 8609.817553935718 9194.688981182791 7077.488686556517 7498.525447577889 8436.485305412913 8723.019359404905 10130.480366254707 0.9631865785263007 0.8187716284933568 0.9868653041861707 0.8498923291550501 0.9076261587565878 0.6986330786575624 0.7401944603294398 0.8327823558609715 0.8610667060233247 1.0 13.306414964900977 RFVS(ph)EGDGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RFVSEGDGGR 10 1 Q53EL6;Q53EL6-2 Q53EL6 PDCD4 Programmed cell death protein 4 1 RFVS(1)EGDGGR 84.169 0.018680000000000002 3991500.0 9865.4 11358.0 12854.0 18522.0 22985.0 24320.0 22958.0 20839.0 20294.0 20940.0 True False 11535.41736946824 12485.547177593016 13160.488109066462 17484.27238913421 18481.25424920308 23044.616387086833 20783.252038473755 20291.998330745617 20590.761357523974 24736.256239051207 0.46633642771120876 0.5047468403032648 0.5320323326975388 0.7068277519510706 0.7471322285231936 0.9316129394999646 0.8401939176900654 0.8203342548946665 0.8324121952220592 1.0 14.594339548656968 -5.981070083350211 1.2005737765481779 0.8721343198408695 0.4679961395623804 0.8936579172343424 0.05685320468475198 0.14446145836470253 0.42290320587667807 0.02105348966016935 0.04174264485481757 1.0445516433150358e-06 5.981070083350211 -0.40413818027848913 RGAAAADLLSS(ph)SPESQHGGTQSPGGGQPLLQPTK ddPTM_PC-9_AZD4547_30min_R2 2 RGAAAADLLSSSPESQHGGTQSPGGGQPLLQPTK 34 1 Q9H3S7 Q9H3S7 PTPN23 Tyrosine-protein phosphatase non-receptor type 23 1 RGAAAADLLS(0.112)S(0.354)S(0.354)PES(0.017)QHGGT(0.082)QS(0.082)PGGGQPLLQPTK;RGAAAADLLS(0.12)S(0.426)S(0.354)PES(0.045)QHGGT(0.045)QS(0.01)PGGGQPLLQPTK 76.04899999999999 1.9187000000000002e-08 28307000.0 18593.8 21093.3 130764.0 229520.0 169608.0 140440.0 76907.0 189498.0 91797.0 143079.0 True False 24506.2416249341 27911.296723036714 129029.98392032007 176607.71004865118 146060.85684718692 131658.26459882644 83751.57401139956 160215.43833083851 96649.20201271011 138069.84775985804 0.1774916248735009 0.20215345476140628 0.9345268790673196 1.2791185976812347 1.0578765691204894 0.9535627563508065 0.6065884432426325 1.1603941116057275 0.7000022349616117 1.0 17.07503876697352 -5.264920642326501 5.897576769351284 0.9708221918456439 0.18262436630574724 0.7337726381171759 0.18599696219218453 0.07149476133777513 11.038252873217477 0.0494468522651915 0.11757775005141075 5.433496074981566e-06 5.264920642326501 -0.7881978255398967 down RGAGAELKDT(ph)QSPSTCSEGLLGWSQK ddPTM_PC-9_AZD4547_30min_R2 1 RGAGAELKDTQSPSTCSEGLLGWSQK 26 2 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RGAGAELKDT(0.41)QS(0.327)PS(0.092)T(0.118)CS(0.052)EGLLGWSQK 57.21 0.024201 0.0 9279.1 6021.3 11555.0 25134.0 18215.0 12154.0 8695.6 10696.0 8297.8 13398.0 True False 12229.660782730041 7967.567472060847 11401.773150097124 19339.74461642906 15686.161663786585 11394.008458659488 9469.491554390706 9043.178969628432 8736.40476770555 12928.940098033809 0.945913639478451 0.6162583639220766 0.8818799579581214 1.4958491933434037 1.2132596751818878 0.8812793912157 0.7324259747967118 0.6994524609951353 0.6757247463026109 1.0 13.658316388805394 -6.9966209102872226 23.638700244103003 0.7597119086462064 1.0274005042192444 0.21572592105175947 0.22803726391124526 86.94628942769413 608226.0888734693 0.09073418268400746 0.079556958119529 1.0078109894499086e-07 6.9966209102872226 0.26768859557303804 RGAGAELKDTQSPS(ph)TCSEGLLGWSQK ddPTM_PC-9_AZD4547_30min_R2 1 RGAGAELKDTQSPSTCSEGLLGWSQK 26 2 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RGAGAELKDT(0.029)QS(0.205)PS(0.255)T(0.255)CS(0.255)EGLLGWSQK 40.177 0.029937000000000002 11560000.0 38517.0 23131.0 37416.0 93221.0 85830.0 53232.0 32446.0 53594.0 37748.0 54487.0 True False 50764.60479663043 30607.643398641387 36919.83939281991 71730.3387000929 73913.98603364287 49903.39462492692 35333.63114376936 45312.27876760154 39743.282215930645 52579.42671455207 0.9654841820970376 0.5821220448980343 0.7021727260978644 1.3642282387274596 1.405758690274692 0.9491049587863893 0.6720048762720781 0.8617872350262951 0.7558713492958483 1.0 15.68221079155901 -12.291619841428645 1.9311866363711885 3.4135243781687916 0.9209642448756903 0.008635124027294605 0.2626222971665718 19602362.41687351 604155.6355326925 208166471.68076235 0.07708487081643517 5.109520648701472e-13 12.291619841428645 -2.492560133293101 RGAGAELKDTQSPSTCS(ph)EGLLGWSQK ddPTM_PC-9_AZD4547_30min_R2 1 RGAGAELKDTQSPSTCSEGLLGWSQK 26 2 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RGAGAELKDT(0.008)QS(0.235)PS(0.235)T(0.235)CS(0.287)EGLLGWSQK 58.015 0.0011366 10343000.0 46559.0 24921.0 48928.0 101970.0 90988.0 55869.0 40243.0 57669.0 32279.0 58695.0 True False 61363.793512638986 32976.22589328354 48279.18275101273 78462.39192079539 78355.88676720356 52375.50259806211 43824.54903897893 48757.58115178591 33985.20204111543 56640.105915367545 1.0833982832646825 0.5822062893483477 0.8523851071739198 1.3852797527962786 1.3833993687138233 0.9247070031317091 0.7737370601753851 0.860831390828262 0.6000201004549074 1.0 15.789536342771077 -6.999363338584785 24.999363301913906 0.8045029028736398 1.049399186847346 0.19522743922881214 0.23806791736641417 42.50698484379881 1669012.3213515254 0.09417169285245655 0.08232103050203546 1.0014670421389721e-07 6.999363338584785 0.24489628397370622 RGALIVLEGVDR ddPTM_PC-9_AZD4547_30min_R2 1 RGALIVLEGVDR 12 1 P23919-2;P23919;G5E9E9 P23919-2 DTYMK Thymidylate kinase 0 160.22 0.00035811 2084400.0 8361.0 6485.4 6387.7 11194.0 11118.0 6978.6 8278.1 9207.6 6133.6 9494.4 False True 11019.624080396366 8581.678721090688 6302.994924350962 8613.396245575987 9574.457610649428 6542.22703880213 9014.834863195372 7784.776989598981 6457.80957400742 9162.003945870445 1.202752601450603 0.9366595748912196 0.6879493789338398 0.9401214293798978 1.045017844045449 0.7140607095842698 0.9839370203784505 0.8496805977809891 0.7048468448780929 1.0 13.16144746885467 -4.798743708670842 3.987667446079021 0.8652621711157424 1.2270030818849953 0.4014233532809125 0.12292007786338163 0.2152925916280624 6.294207532915822 0.03013126697013754 0.216015578495275 1.5894844784764607e-05 4.798743708670842 0.36174091076925285 RGALIVLEGVDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGALIVLEGVDR 12 1 P23919-2;P23919;G5E9E9 P23919-2 DTYMK Thymidylate kinase 0 184.34 0.00030934 1800000.0 7288.2 6281.6 9429.2 8413.4 9285.6 8527.7 9352.0 8831.5 8847.0 7058.3 False True 8521.948311488472 6905.195734351852 9654.027888440136 7942.024474610831 7466.153337237338 8080.492399842125 8466.110857383328 8599.682482747727 8976.370638120361 8337.913916527947 1.0220719950820936 0.8281682688836509 1.157846912919466 0.9525193656494392 0.895446200570319 0.9691263882953333 1.0153751816268168 1.0313949710731465 1.076572716867084 1.0 13.025470762008757 -7.43598314057048 2.956173426372935 1.0393482692121765 0.9687248762979491 0.11696674477336533 0.08186088641582563 0.5857796981236442 9.919630416736412 0.0398160380663594 0.023992711800826263 3.664518001299352e-08 7.43598314057048 -0.07062339291422737 RGAPS(ph)SPATGVLPSPQGK ddPTM_PC-9_AZD4547_30min_R2 2 RGAPSSPATGVLPSPQGK 18 1 Q5SRE5-2;Q5SRE5 Q5SRE5-2 NUP188 Nucleoporin NUP188 homolog 1 RGAPS(0.469)S(0.469)PAT(0.046)GVLPS(0.017)PQGK;RGAPS(0.5)S(0.5)PATGVLPSPQGK 110.38 0.0013563 20724000.0 70671.0 56144.0 93827.0 136983.0 107124.0 89103.0 79160.0 101179.0 72635.0 93743.0 True False 93142.90795188253 74291.45004424041 92582.79267452718 105403.68571625285 92251.68169483787 83531.37532433229 86205.08664676004 85544.11041211977 76474.33781270849 90461.08610314864 1.0296461380717443 0.8212531293237986 1.023454356594384 1.1651826244498749 1.0197940978693036 0.9233956712512303 0.952952151696082 0.9456454050814483 0.8453838120571346 1.0 16.465009697055585 -6.7620796529186045 24.95577582108561 0.9312955343896285 1.0104378474425524 0.17314788555778315 0.08555769825308823 34.34086568938542 1338451.7200887 0.03155667100422379 0.02949513171773933 1.7294991268007558e-07 6.7620796529186045 0.07914231305292385 RGAPS(ph)SPATGVLPSPQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RGAPSSPATGVLPSPQGK 18 1 Q5SRE5-2;Q5SRE5 Q5SRE5-2 NUP188 Nucleoporin NUP188 homolog 1 RGAPS(0.497)S(0.497)PAT(0.006)GVLPSPQGK;RGAPS(0.499)S(0.499)PAT(0.002)GVLPSPQGK;RGAPS(0.7)S(0.262)PAT(0.038)GVLPSPQGK 97.77600000000001 0.00034465 31659600.0 90821.0 71584.0 81777.0 115667.0 125519.0 135141.0 113635.0 124680.0 124253.0 96148.0 True False 106195.20150348448 78690.38643782504 83726.87382099955 109186.5529874738 100924.45299568068 128053.96805786598 102870.67015384467 121407.28210937994 126069.96506141868 113578.87129285082 0.9349908155863924 0.692825923889756 0.7371694476970005 0.9613280335032394 0.8885847503754277 1.127445330282361 0.9057201307151908 1.0689248865340844 1.109977266250172 1.0 16.793334954384086 -6.16558840584789 1.5094342803515228 1.034617768076779 0.7829670090419066 0.5396010805188951 0.09370327983846156 0.2919201069275786 1.3299822398426633 0.033234444016421026 0.0495284025769161 6.82985673906525e-07 6.16558840584789 -0.25165075903487233 RGAPS(ph)SPATGVLPSPQGK ddPTM_PC-9_Lapatinib_30min_R1 1 RGAPSSPATGVLPSPQGK 18 1 Q5SRE5-2;Q5SRE5 Q5SRE5-2 NUP188 Nucleoporin NUP188 homolog 1 RGAPS(0.719)S(0.272)PAT(0.008)GVLPSPQGK 78.531 0.0020346 7743300.0 74382.0 39958.0 53662.0 48165.0 45162.0 42635.0 38502.0 33368.0 58330.0 35568.0 True False 73321.29904001184 39865.479706012185 49250.11750131025 51707.21477372988 42505.65995190822 40811.60043703923 40495.44516826716 34918.39909587292 51760.261157869434 41715.881408619076 1.7576351395241683 0.9556427518699252 1.1806083399962513 1.2395091036730788 1.0189323230534921 0.9783228607176688 0.9707440859657885 0.837052890093275 1.2407807149239583 1.0 15.348309107764983 -4.756972525285891 24.99998551159311 1.0465608787701024 1.7576361970956489 0.7416235028992382 0.12586292605495547 70.66668579994366 395456.31841194443 0.03239198357649433 0.2505775135631431 1.7499573924449198e-05 4.756972525285891 0.7110753183255465 RGAPSS(ph)PATGVLPSPQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGAPSSPATGVLPSPQGK 18 1 Q5SRE5-2;Q5SRE5 Q5SRE5-2 NUP188 Nucleoporin NUP188 homolog 1 RGAPS(0.24)S(0.752)PAT(0.008)GVLPSPQGK 107.57 0.00013407 12503000.0 23509.0 17307.0 19338.0 28457.0 32605.0 35382.0 30229.0 31415.0 28331.0 25134.0 True False 27488.60937608497 19025.12458202169 19799.09125977339 26862.6465488388 26216.284306950907 33526.50563354879 27365.490280992366 30590.389536943883 28745.287278013795 29690.59523936548 0.9258355770395269 0.6407794935952345 0.66684723226844 0.9047527114991205 0.8829827794153438 1.1291961431981479 0.9216888398623158 1.0303057008565932 0.9681613671355991 1.0 14.857718396426478 -6.118477651166805 2.0449149838229874 1.0006857310528117 0.7384226944383764 0.564096519537445 0.09491346490581228 0.22301714533408631 1.8402714675674177 0.03042377808930716 0.04388591307865715 7.612413115443241e-07 6.118477651166805 -0.2622630366144353 RGAPSSS(ph)GGS(ph)S(ph)S(ph)S(ph)GPK ddPTM_PC-9_Lapatinib_30min_R1 1 RGAPSSSGGSSSSGPK 16 1 G5E9L9;A0A0U1RR70;Q8N568-2;Q8N568;Q8N568-3 G5E9L9 DCLK2 Serine/threonine-protein kinase DCLK2 5 RGAPS(0.553)S(0.59)S(0.613)GGS(0.766)S(0.766)S(0.766)S(0.947)GPK 40.187 0.045207 0.0 16213.0 13434.0 15422.0 15968.0 14079.0 14161.0 12718.0 12009.0 16558.0 14761.0 True False 15981.79964689994 13402.894398382505 14154.062690641547 17142.339987686464 13250.90090037899 13555.367040903315 13376.475810348082 12566.981981009898 14693.063676530113 17312.41918220385 0.9231407510816451 0.7741780196819572 0.8175670044537215 0.9901758851419092 0.7653985708710277 0.7829851448396904 0.7726520291339939 0.7258940445439317 0.8487007807455195 1.0 14.079519715941261 RGAQPGRHS(ph)VTGYGDCAVGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RGAQPGRHSVTGYGDCAVGAR 21 2 Q96IF1;H0YJL9 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 RGAQPGRHS(0.695)VT(0.296)GY(0.009)GDCAVGAR;RGAQPGRHS(0.906)VT(0.091)GY(0.003)GDCAVGAR 45.236999999999995 0.023941999999999998 6975000.0 16596.4 16316.4 20572.4 30282.0 27099.0 32326.0 28236.5 32520.0 27502.1 21704.0 True False 19405.842726158364 17936.184360669013 21062.92403726146 28585.397715568608 21789.1454817992 30630.767653329338 25561.73430544317 31666.38445778817 27904.266183638538 25638.763391230535 0.7568946454256809 0.6995729118044708 0.8215265188829586 1.1149288785646323 0.849851654282669 1.1947053446347675 0.996995600582916 1.235097963758241 1.0883624049193765 1.0 14.646039059120664 -5.652652580675112 0.989786643122989 1.0983139811546472 0.676246097399808 0.6185036177544885 0.10911714100977066 0.4367679450410137 0.7611373932006485 0.040452379497736 0.14652395942879193 2.2250891669021824e-06 5.652652580675112 -0.42206788375483917 RGAS(ph)GSIFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGASGSIFSK 10 1 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 RGAS(0.843)GS(0.157)IFSK 65.092 0.022789 11180000.0 39601.0 44371.0 73137.0 78221.0 96669.0 79299.0 78905.0 82869.0 79644.0 62404.0 True False 46304.66714459743 48775.85964227679 74880.86345361703 73838.53096590363 77727.4033942227 75140.42084208888 71430.54717727029 80693.77655696322 80808.64282835514 73717.3512102079 0.628137967309187 0.661660502466923 1.0157834244490327 1.0016438430533157 1.0543976705372928 1.0193044053878584 0.9689787547246957 1.0946374935103376 1.0961956920823992 1.0 16.16971661296312 -5.256188074777244 4.464384302862188 1.0336949501582517 0.6350088852170572 0.9422850271325093 0.038319409797574366 0.04055834441863184 2.1712694363506806 0.010666156403660016 0.027346562140094403 5.54385579756512e-06 5.256188074777244 -0.3986860649411945 RGAT(ph)PPAPPR ddPTM_PC-9_AZD4547_30min_R2 2 RGATPPAPPR 10 1 Q6SPF0 Q6SPF0 SAMD1 Atherin 1 RGAT(1)PPAPPR;RGAT(1)PPAPPR 84.352 0.010695999999999999 36531000.0 20920.6 25487.8 31252.4 45794.0 35882.0 32981.1 33322.4 41842.0 34969.0 39550.8 True False 27572.91562448752 33726.232908905426 30837.972756044615 35236.900810247156 30900.403668404637 30918.78660324952 36288.02904595759 35376.28033350719 36817.38994937157 38166.138530326614 0.7224444674322561 0.883668985326004 0.8079929996465565 0.9232503514142019 0.8096287667103481 0.8101104223232227 0.9507912103060495 0.9269022671863275 0.9646611202261572 1.0 15.220005608414718 -7.2690657716148985 23.717004438462936 0.9544971940250876 0.8316285937907198 0.6102775601595771 0.05242004774124907 216.00400372069066 671736.9194989932 0.02095862190336855 0.014460942450786657 5.381882705614554e-08 7.2690657716148985 -0.12286860023436774 RGAT(ph)PPAPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RGATPPAPPR 10 1 Q6SPF0 Q6SPF0 SAMD1 Atherin 1 RGAT(1)PPAPPR;RGAT(1)PPAPPR 85.973 0.0098162 35689000.0 17624.699999999997 21474.0 24474.0 18096.8 22495.0 25566.0 22469.0 18965.1 20754.5 17830.5 True False 20608.213606307578 23605.796803278066 25057.55297816187 17082.894966617205 18087.26623170866 24225.273953629217 20340.57365852718 18467.286220184444 21057.995298843576 21063.02850383967 0.9784069561768299 1.1207218752505066 1.18964625498152 0.8110369771138605 0.8587210632322629 1.1501325153319282 0.9657003338726533 0.876763102552796 0.9997610407736393 1.0 14.362425265739624 -5.7492532060734005 24.999716184839766 0.9515692400622138 1.0987046858415739 0.30169678717950554 0.10074118306518842 293.1113218103367 601307.0739565823 0.028526809078265814 0.048942439283672166 1.7813398926515315e-06 5.7492532060734005 0.1471354457793601 RGAT(ph)PPAPPR ddPTM_PC-9_Lapatinib_30min_R1 1 RGATPPAPPR 10 1 Q6SPF0 Q6SPF0 SAMD1 Atherin 1 RGAT(1)PPAPPR 69.86399999999999 0.031642 5083800.0 5133.1 4195.2 5282.0 3358.8 5996.0 3963.6 3610.3 4661.7 5605.7 4416.5 True False 5059.901052704748 4185.486272152319 4847.734349109631 3605.8173566283367 5643.327068589561 3794.086067602881 3797.2236686664305 4878.2996003725375 4974.327035362057 5179.886140383665 0.9768363465089542 0.8080266937763823 0.9358766231009409 0.696119037929521 1.0894693272488745 0.7324651478385313 0.7330708756438373 0.9417773804601832 0.960315902811257 1.0 12.338704670892605 -7.979956920285563 24.758879679119083 0.9704542511923558 0.8518713070273495 0.17310951334271196 0.11604059789784758 352.15225947151816 435007.4792280197 0.06133004329491215 0.029456644435406187 1.0472324228135763e-08 7.979956920285563 -0.11858294416500637 RGDDSFGDK ddPTM_PC-9_AZD4547_30min_R2 1 RGDDSFGDK 9 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 79.07 0.042408 0.0 30467.0 30795.0 38761.0 42138.0 41173.0 38965.0 35913.0 37950.0 43356.0 47100.0 False True 40154.87224703216 40748.881520952884 38247.00381401251 32423.735125610216 35456.839647712615 36528.5123902968 39109.18742730039 32085.69950424449 45647.70964697171 45451.04333612423 0.8834752582041894 0.8965444691687837 0.8414989185432847 0.7133771360500324 0.7801105771213775 0.8036891941106254 0.860468419571276 0.7059397793569011 1.004326992218706 1.0 15.472025791649273 -8.283089709082303 24.460725146098905 1.0021636240936918 0.811700001442112 0.6098572954939677 0.06127042336959172 494.28711928686783 558442.8367375694 0.06186601027979092 0.01603965326753572 5.210870627869458e-09 8.283089709082303 -0.1904636226515798 RGDDWNDR ddPTM_PC-9_AZD4547_30min_R2 1 RGDDWNDR 8 1 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;C9JUL9;A0A087X0F4 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 0 86.67 0.031559 0.0 2849.6 3240.3 5660.6 5498.0 4168.7 4394.2 3786.3 5546.4 3010.0 3240.8 False True 3755.7135246379 4287.663607479903 5585.536745429665 4230.521043253243 3589.9479619998424 4119.4299793517785 4123.273364964987 4689.331323592662 3169.102454963211 3127.340578422748 1.2009288500749309 1.3710254767462375 1.7860340456576336 1.3527535416007925 1.1479235701953534 1.3172310070012854 1.3184599699226014 1.4994629481505632 1.013353798696759 1.0 11.61072062706084 -8.274899177513687 23.80228645440118 1.0066766481539318 1.375829522812031 0.4414549898689146 0.16536449326771205 464.685622845722 821734.1438433515 0.16537920301100512 0.043827011073438664 5.31007704611471e-09 8.274899177513687 0.3691528746580992 RGDDWNDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGDDWNDR 8 1 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;C9JUL9;A0A087X0F4 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 0 82.287 0.039452 0.0 5856.3 10750.0 7808.9 6768.5 8062.7 7081.5 7093.2 5956.2 7141.1 5304.3 False True 6847.655922802602 11817.18895572503 7995.093791418161 6389.282888773077 6482.871813576235 6710.133673731723 6421.280745679157 5799.856061115555 7245.525077866097 6265.927601184304 1.0928399366613089 1.8859440625345718 1.2759633210423678 1.019686676169935 1.0346228405752609 1.0708923085008932 1.024793319422569 0.9256181096026935 1.1563371840582137 1.0 12.61331238504201 -5.556894768768059 4.709332255205806 1.0349303274307702 1.5117098693363875 0.4930554468596505 0.18646331610283493 0.13101451263351468 6.908856768407219 0.047064644309551464 0.08733948752593272 2.7739921722538134e-06 5.556894768768059 0.47677954190561733 RGDDWNDR ddPTM_PC-9_Lapatinib_30min_R1 3 RGDDWNDR 8 1 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;C9JUL9;A0A087X0F4 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 0 ;; 123.21 0.002085 5191100.0 18935.7 30363.3 24576.800000000003 21178.5 32862.4 27186.7 30104.0 27235.1 26064.9 24648.300000000003 False True 18665.67344561792 30292.99564436558 22556.1903731915 22736.037539404933 30929.49824196424 26023.988216293073 31662.637819996744 28500.54217262075 23129.19648643495 28908.725813204717 0.6456761036867266 1.0478841523526632 0.7802554328730894 0.7864766398323835 1.069901815867529 0.9002122191219519 1.0952623102307095 0.985880261785958 0.8000766493786511 1.0 14.819217401249851 -6.248978427777178 24.803035464588906 0.9767677301201229 0.8292154650286229 0.29359437191108473 0.12089027300261242 972.3026101891586 1935329.3124260334 0.0346810862695531 0.044457965192040226 5.636656534625627e-07 6.248978427777178 -0.1475522650915 RGDDWNDREWDR ddPTM_PC-9_AZD4547_30min_R2 1 RGDDWNDREWDR 12 2 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;C9JUL9 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 0 104.07 0.0079173 26382000.0 12946.0 11267.0 26589.0 37658.0 32834.0 25323.0 22604.0 23986.0 17629.0 24829.0 False True 17062.55870647187 14908.837411806337 26236.412487056026 28976.529910300193 28275.56585609492 23739.548806864757 24615.71221024973 20279.514843446846 18560.832949683194 23959.744267359438 0.7121344249786647 0.6222452646173178 1.0950205559079407 1.2093839394511052 1.1801280322768286 0.990809774176319 1.027377919211931 0.8463994697586903 0.7746674064033635 1.0 14.548324889254559 -5.258719911198467 24.996750216580548 1.0223378756316752 0.6671898140379425 0.5430094191137889 0.12767935532917873 190.1405787894311 1747706.6576230885 0.03743990728156968 0.09019389304543537 5.511630424502342e-06 5.258719911198467 -0.3551480615937327 RGDDWNDREWDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RGDDWNDREWDR 12 2 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;C9JUL9 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 0 ; 129.0 0.00076237 30496000.0 30646.0 28231.0 40411.0 44259.0 47894.0 36341.0 41266.0 37229.0 35625.0 26055.0 False True 35833.76251390956 31033.58710782077 41374.55149957095 41779.311719613994 38509.51450995572 34435.21398532579 37356.98574003215 36251.778197386084 36145.948229121524 30778.56524873349 1.164244084294478 1.008285696783666 1.3442651132438177 1.3574158308543371 1.2511796504725103 1.1188050419843 1.2137338254118053 1.1778254738133973 1.1743870429635734 1.0 14.90963836115771 -9.300728194167345 0.6858855716590878 0.9940291630239534 1.2127310055283669 0.2903396131513676 0.09625978525951173 4.30975147772997 2.680382674684607 0.16939169096224202 0.03938959523225357 5.003475825712819e-10 9.300728194167345 0.2187018425044135 RGDDWNDREWDR ddPTM_PC-9_Lapatinib_30min_R1 1 RGDDWNDREWDR 12 2 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;C9JUL9 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 0 86.463 0.036897000000000006 18441000.0 21878.0 14415.0 15605.0 12407.0 17139.0 13486.0 10101.0 7815.3 18188.0 6918.9 False True 21566.015708066163 14381.622953154965 14322.017137041983 13319.452168538708 16130.91771657046 12909.235217401452 10623.980355427413 8178.4273691553535 16139.475911869189 8114.822646145261 2.657607768952356 1.77226583750251 1.7649205363527312 1.6413731697347411 1.9878336742495586 1.5908216088411562 1.3092067219083416 1.0078380915743494 1.9888883116300555 1.0 12.986343848896485 -1.5228787452803376 0.26824447312024186 1.255430674582683 9.245904672837117 0.5417170874996928 0.3191175556890841 42.31406953239567 0.5897865587698133 0.37414604440920696 156.18332607268576 0.029999999999999995 1.5228787452803376 7.9904739982544335 RGDIVFVDR ddPTM_PC-9_AZD4547_30min_R2 1 RGDIVFVDR 9 1 O15269 O15269 SPTLC1 Serine palmitoyltransferase 1 0 101.97 0.005229800000000001 0.0 4074.8 3948.6 6857.9 7646.2 6667.7 5128.2 6125.2 5389.4 5473.3 5696.6 False True 5370.501638894765 5224.907730918483 6766.959765127743 5883.486722612388 5742.004947879763 4807.532843318876 6670.330933915303 4556.592066091571 5762.607464036588 5497.163767910095 0.976958640061858 0.9504733625399853 1.2309911166609462 1.0702767774461202 1.0445395462654647 0.8745478661892946 1.213413173690334 0.8288987300489122 1.048287390977149 1.0 12.424471744505718 -6.542617516872987 24.988285302307883 0.9920467141479514 1.061398826122443 0.06342486787418522 0.11871292617352901 704.7478950142894 892168.25218503 0.03858556560543348 0.03858987669644011 2.866701562392447e-07 6.542617516872987 0.06935211197449154 RGDLPFVVPR ddPTM_PC-9_AZD4547_30min_R2 2 RGDLPFVVPR 10 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 144.17 7.8638e-05 28533000.0 54665.0 52959.0 71602.0 93218.0 72025.0 75605.0 61332.0 77316.0 58938.0 70471.0 False True 72047.33289736471 70076.96108030996 70652.51069608424 71728.0303037432 62025.57199199714 70877.40739813645 66790.42918417248 65368.58874493184 62053.342355688284 68003.83173970295 1.059459901805813 1.030485478355724 1.0389489663835354 1.0547645400085 0.9120893691610101 1.0422560844723079 0.982156850217279 0.9612486101539399 0.9124977338513623 1.0 16.05332841820836 -6.14391362574543 0.7290393321909164 0.9622331725955215 1.0580428585240602 0.39933905319472507 0.04098682850636703 0.8510755759786719 0.9400337195944812 0.023648813137040998 0.049376807004165135 7.179370633192165e-07 6.14391362574543 0.09580968592853867 RGDLPFVVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RGDLPFVVPR 10 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 160.77 8.358600000000001e-05 22817000.0 81144.0 77255.0 74397.0 85951.0 103375.0 94244.0 96561.0 82502.0 77304.0 68571.0 False True 94880.07653294626 84924.36583949176 76170.90663219373 81135.44412690161 83119.41083364651 89301.67873291983 87414.0430389001 80336.40991809475 78434.4247552003 81002.37949226261 1.1713245601878801 1.0484181621800848 0.9403539391021175 1.0016427250097228 1.0261354216339549 1.102457474615915 1.0791540148181689 0.9917783949268864 0.9682977863964157 1.0 16.305676668179615 -4.794573891962197 4.0287148897815594 1.0176534332264624 1.1826740277515797 0.5149935429049415 0.04562199969243545 0.19830503272605482 6.0111121348433665 0.01272924419261058 0.09220163271474321 1.6048191868693493e-05 4.794573891962197 0.1650205945251173 RGDLPFVVPR ddPTM_PC-9_Lapatinib_30min_R1 2 RGDLPFVVPR 10 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 169.65 7.8638e-05 36108000.0 77420.0 67831.0 70757.0 57693.0 67491.0 67083.0 56216.0 57062.0 62866.0 58176.0 False True 76315.9766029109 67673.94148702436 64939.63258991864 61935.935678206144 63521.31207241128 64214.016468110785 59126.589412999456 59713.3088350726 55785.36907167185 68231.64408535277 1.1184836248038406 0.9918263350413956 0.9517524230939522 0.9077303721529681 0.9309655794450854 0.9411178248582691 0.8665567158111629 0.8751556500730898 0.8175879362057941 1.0 16.058153358932103 -1.522878780861412 0.6028608317340015 0.8925753636461017 15.369864790104858 0.6670601157175695 0.04615641681238807 98.16588553404343 0.7529950777152742 0.020396377707088367 1873.6322627584404 0.029999997542146557 1.522878780861412 14.477289426458755 RGDS(ph)QECSPR ddPTM_PC-9_AZD4547_30min_R2 1 RGDSQECSPR 10 1 Q13111;Q13111-3;Q13111-2 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 RGDS(0.999)QECS(0.001)PR 95.273 0.008785 1578400.0 4067.5 3364.8 5440.6 6016.5 5765.1 5839.0 3570.0 7258.8 5931.3 6308.1 True False 5360.8803907441925 4452.405797749711 5368.454089175115 4629.488878998386 4964.715377869672 5473.886406953493 3887.7230839936087 6137.119250630032 6244.816409011058 6087.255339036207 0.8806728307199577 0.7314307598035897 0.8819170200974517 0.7605215521863374 0.815591773525921 0.8992371934606855 0.6386660107819874 1.0081915261996748 1.0258837622539745 1.0 12.57157616774989 -7.850591425207555 11.430282284330175 1.0138020940523058 0.8043883879499311 0.6233952592022729 0.07484268585357753 0.2911945563247966 35.50353576374975 0.038028235460729094 0.01826090353303692 1.4106152504889984e-08 7.850591425207555 -0.20941370610237475 RGDS(ph)QECSPR ddPTM_PC-9_Lapatinib_30min_R1 1 RGDSQECSPR 10 1 Q13111;Q13111-3;Q13111-2 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 RGDS(0.998)QECS(0.002)PR 112.08 0.0016718 0.0 4532.1 4426.3 4718.6 4509.4 5818.0 4551.0 3874.8 5723.9 5199.5 5421.9 True False 4467.471422914651 4416.051174301062 4330.654922322737 4841.0363189174195 5475.7966786280995 4356.364338899156 4075.41818445799 5989.853290124283 4613.877556837686 6359.0681907723765 0.702535542769833 0.6944494133132869 0.68102036216673 0.7612807684531882 0.8611004811324418 0.6850633156003363 0.6408829190370715 0.941938836072892 0.7255587482978825 1.0 12.63459966415916 -14.522878745110624 0.14789251494206127 1.92628978844934 0.6625583389649226 0.4852146304611151 0.08332464845873919 118.25775706376201 1.0419449752205898 31.987556814552335 0.4423064920948124 3.000000001172338e-15 14.522878745110624 -1.2637314494844174 RGDSQECS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 RGDSQECSPR 10 1 Q13111;Q13111-3;Q13111-2 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 RGDS(0.011)QECS(0.989)PR;RGDSQECS(1)PR 105.25 0.0036538000000000005 5693900.0 16003.2 13712.7 12683.3 11374.3 10711.2 11256.1 8420.7 12344.5 15413.8 19871.7 True False 21091.88471276152 18145.06210853614 12515.111154878992 8752.13086618322 9224.134768770296 10552.2542876022 9170.125986942574 10436.94117338988 16228.542000103631 19175.997831474746 1.0999106746947014 0.9462382228033804 0.6526445854273706 0.4564107142220161 0.48102502147920334 0.5502844952496884 0.47820854317635986 0.544271086444278 0.8462945262471153 1.0 14.227014030501406 -5.187379745450256 2.677809732468831 0.5860515865431956 1.0804412392638192 0.47193878546346013 0.16840196605521238 0.22212714274270218 3.0012189424156572 0.043718464224652406 0.15905892352525108 6.495614678659608e-06 5.187379745450256 0.49438965272062363 RGDSQECS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RGDSQECSPR 10 1 Q13111;Q13111-3;Q13111-2 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 RGDS(0.002)QECS(0.998)PR;RGDS(0.16)QECS(0.84)PR 84.169 0.018680000000000002 5765500.0 3750.85 7366.8 5577.1 4606.57 13668.900000000001 12529.099999999999 4436.92 10586.9 13447.3 15487.2 True False 4385.794822335629 8098.127218514895 5710.079215269535 4348.478817601442 10990.577168019661 11872.051939780005 4016.622817080971 10309.005092747768 13643.941322707811 18294.90676339225 0.23972763999604077 0.4426438091895111 0.31211305360108704 0.23768794636891305 0.6007451860870694 0.6489266162064159 0.21954869019164144 0.563490441688169 0.7457781282607612 1.0 14.159154442816808 -9.561105828320052 0.2168708573182125 1.2947115884142721 0.23481851984947097 0.6537086958467127 0.14420985367708467 5.879660982186077 0.4789326263035089 1.6552594045771283 0.4250744918094737 2.7472246313714033e-10 9.561105828320052 -1.0598930685648011 RGDSQECS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 RGDSQECSPR 10 1 Q13111;Q13111-3;Q13111-2 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 RGDS(0.414)QECS(0.586)PR 98.105 0.007180199999999999 2658200.0 2604.6 5787.5 3035.0 5844.7 6654.7 2801.7 8560.2 7545.0 7012.2 4656.0 True False 2567.4579263748597 5774.099399332939 2785.4740154387973 6274.538735347639 6263.283629643587 2681.877822081689 9003.405270619716 7895.568244376691 6222.412194260448 5460.78339626997 0.47016293085870825 1.0573756511340446 0.5100868892440299 1.1490180584041314 1.1469569794549572 0.491115949391724 1.6487387646192966 1.4458673181891484 1.1394724424540836 1.0 12.414892217646276 -6.335797465537863 0.683574622709616 1.2814681098988827 0.675550710561963 0.2765829737662018 0.3256095319777296 1.0737762485410018 1.0906461458762946 0.2138376485390088 0.3597725476081763 4.615327614909601e-07 6.335797465537863 -0.6059173993369197 RGDYDDPK ddPTM_PC-9_Lapatinib_30min_R1 1 RGDYDDPK 8 1 Q12789;Q12789-3;H3BRD0 Q12789 GTF3C1 General transcription factor 3C polypeptide 1 0 97.431 0.015477000000000001 0.0 11604.0 11428.0 9814.0 7822.8 9756.2 8621.0 9464.1 9621.1 6957.8 7869.3 False True 11438.524832087021 11401.53916813422 9007.130803135533 8398.1148080958 9182.359497427196 8252.299926532554 9954.104789803048 10068.131429552366 6174.139295117846 9229.498019816858 1.2393441991673992 1.2353368670380258 0.9759069002231893 0.9099210802217003 0.9948926233812013 0.8941222923298602 1.0785098786987517 1.0908644660776632 0.6689572154261495 1.0 13.17203646839286 -5.2716397158484165 5.1844543684284154 0.9563376739529902 1.2408613975655651 0.5110206181987029 0.11184779656790131 0.12971912784241305 11.601802901135263 0.02857202518512211 0.0681497099785336 5.350080099239701e-06 5.2716397158484165 0.28452372361257494 RGEAAGS(ph)PVPTPPR ddPTM_PC-9_AZD4547_30min_R2 2 RGEAAGSPVPTPPR 14 1 A0A087WSV0;Q9HB09;I6LJZ7;M0R1Z8;M0R1K0;I6LK00;M0QZM6;I6LJZ9;Q9HB09-2 A0A087WSV0 BCL2L12 Bcl-2-like protein 12 1 RGEAAGS(1)PVPTPPR;RGEAAGS(1)PVPTPPR 80.459 0.0053051 9944800.0 29691.0 34836.0 43145.0 54620.0 45352.0 37854.0 38215.0 58124.0 36907.0 42561.0 True False 39132.1203888349 46096.055744890866 42572.86910955779 42028.20287058787 39055.65763250339 35486.98339592697 41616.06096773549 49142.27135664574 38857.82867286617 41070.95234456016 0.9527931093620706 1.1223517623397958 1.0365688322101096 1.023307239578887 0.9509313858819323 0.8640409187060697 1.013272363849813 1.1965213502811465 0.94611462492695 1.0 15.325830780161882 -10.64259818402747 11.903042329190267 0.9999979546532236 1.0154323182321718 4.5826596833609123e-05 0.08974785584666788 0.0 0.0 0.09056275503246773 0.02196469439681188 2.2772033601763097e-11 10.64259818402747 0.01543436357894823 RGEAAGS(ph)PVPTPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RGEAAGSPVPTPPR 14 1 A0A087WSV0;Q9HB09;I6LJZ7;M0R1Z8;M0R1K0;I6LK00;M0QZM6;I6LJZ9;Q9HB09-2 A0A087WSV0 BCL2L12 Bcl-2-like protein 12 1 RGEAAGS(1)PVPTPPR;RGEAAGS(0.992)PVPT(0.008)PPR 74.14699999999999 0.0087102 8032200.0 34943.0 39481.0 48166.0 41191.0 51324.0 46318.0 45483.0 35666.0 43273.0 35882.0 True False 40858.159744291 43400.41275916093 49314.46011057224 38883.201813023836 41267.430632416756 43889.00254182109 41174.520971596015 34729.8052912507 43905.78576052701 42387.12255824429 0.9639286009128754 1.023905614246975 1.16343023857798 0.9173352534037735 0.9735841487166541 1.0354324590331194 0.9713922174126814 0.8193480282491068 1.0358284099185058 1.0 15.37133841218798 -5.802720453671276 24.99991742858033 0.9607716040425045 1.0477709649744469 0.21493462100485672 0.07475773704115654 218.6608316165394 132420.5822138804 0.02135622540402667 0.03167680452141927 1.5749963306504667e-06 5.802720453671276 0.08699936093194238 RGEAAGS(ph)PVPTPPR ddPTM_PC-9_Lapatinib_30min_R1 2 RGEAAGSPVPTPPR 14 1 A0A087WSV0;Q9HB09;I6LJZ7;M0R1Z8;M0R1K0;I6LK00;M0QZM6;I6LJZ9;Q9HB09-2 A0A087WSV0 BCL2L12 Bcl-2-like protein 12 1 RGEAAGS(1)PVPTPPR;RGEAAGS(1)PVPTPPR 128.94 1.1054000000000001e-05 9098000.0 44220.0 38267.0 45370.0 29788.0 41533.0 37350.0 30014.0 28694.0 39571.0 29513.0 True False 43589.41469104516 38178.395112617465 41639.85373326465 31978.70888985501 39090.1105970197 35752.62756710249 31567.978060370126 30027.227992597054 35114.09727889681 34614.28272639941 1.2592898438944293 1.10296652437925 1.202967401127368 0.9238587765236482 1.1293058101477484 1.0328865644768914 0.9119928415068399 0.8674808670727148 1.0144395467168297 1.0 15.079079832635811 -5.07759018798213 0.47564532359774825 0.942994665095887 1.3777573075309923 0.552722774826092 0.08145054645210074 2.779008526809468 0.597859664509926 0.057692566614921705 0.6584383363533411 8.363918879775718e-06 5.07759018798213 0.4347626424351053 RGEAHLAVNDFELAR ddPTM_PC-9_AZD4547_30min_R2 4 RGEAHLAVNDFELAR 15 1 Q02790 Q02790 FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed 0 ;;; 139.64 2.5047e-05 24538200.0 27049.699999999997 23106.1 45739.799999999996 52276.4 44901.7 35082.5 32039.3 46071.700000000004 32634.699999999997 41615.7 False True 35650.94193128783 30574.694960587403 45133.26036614561 40224.883642328816 38667.87401475962 32888.78572905395 34890.73563165167 38952.37738734386 34359.7036169395 40158.74700983324 0.8877503554221542 0.7613458396274392 1.1238712292267066 1.0016468798809728 0.9628755101669738 0.8189694195638331 0.8688203250740952 0.9699599785273681 0.8555970037742016 1.0 15.293426636116514 RGEAHLAVNDFELAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RGEAHLAVNDFELAR 15 1 Q02790 Q02790 FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed 0 ;;; 130.66 4.645e-06 22211000.0 53494.1 44790.6 67819.8 66667.0 70874.1 70045.3 67121.7 69545.5 65114.4 49144.2 False True 62549.594573364564 49237.11475723699 69436.88124002384 62931.86412733013 56986.828878983935 66372.00116029661 60763.446656974666 67720.00431454822 66066.57491565781 58053.65443472685 1.0774445671407777 0.8481311854811342 1.1960811410777907 1.0840293301102715 0.9816234556440816 1.1432872194966222 1.0466773754147483 1.166507172958247 1.1380261166838403 1.0 15.825099266087536 -5.26527990558869 24.99929435393258 1.0961007115992678 0.9627878799843679 0.2834230802503078 0.08376071026114225 364.97426855192623 2375755.554562408 0.02085565181502133 0.04623967509071091 5.42900315963194e-06 5.26527990558869 -0.13331283161489993 RGEAHLAVNDFELAR ddPTM_PC-9_Lapatinib_30min_R1 2 RGEAHLAVNDFELAR 15 1 Q02790 Q02790 FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed 0 ; 115.26 6.4603e-05 8801700.0 27483.0 19515.9 29609.0 28691.0 20045.5 32660.0 16719.7 18943.4 37629.0 17947.6 False True 27091.087380235043 19470.71213260332 27174.662314045258 30801.03185037028 18866.463100969333 31263.207934178525 17585.364255879602 19823.57952028168 33390.8257690634 21049.818746326244 1.2869986058651057 0.9249824127821281 1.290968945696407 1.4632445163332288 0.8962767484286313 1.4852008138851451 0.835416421766041 0.9417458534526063 1.5862761656743951 1.0 14.361520190280451 -7.268454649595173 24.991388699434275 1.0860051352301452 1.2099313068417845 0.05812158021233693 0.2594794552108159 2043.6029324085118 7280153.005878887 0.10492820456946442 0.07246119016631611 5.3894612089531094e-08 7.268454649595173 0.12392617161163932 RGEDSDYR ddPTM_PC-9_AZD4547_30min_R2 1 RGEDSDYR 8 1 A0A5F9ZHV7;F8VS29;A0A0A0MS86;J3KNF5;O15078 A0A5F9ZHV7 CEP290 Centrosomal protein of 290 kDa 0 67.032 0.030012999999999998 2951600.0 11158.0 4730.3 7209.7 16252.0 11567.0 10178.0 8635.1 6997.6 6918.9 11612.0 False True 14706.011899182233 6259.276968941824 7114.094667265707 12505.352490897 9961.121710953588 9541.568051031452 9403.607171594733 5916.281708851152 7284.618928785701 11205.467414417717 1.312396114798431 0.5585913320213856 0.6348771009866334 1.1160045385350692 0.8889519145035334 0.8515100439946505 0.8391981185448285 0.5279816976879395 0.6500950526537442 1.0 13.451915208888426 -7.549807885844322 23.45068881660616 0.6901406559848309 0.8740052947806037 0.08598054741236683 0.23066422242828077 249.60325495496804 217356.43286319217 0.10692802724006262 0.061738107640053254 2.8196299446514876e-08 7.549807885844322 0.18386463879577286 RGEEGHDPKEPEQLRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGEEGHDPKEPEQLRK 16 3 P51991 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 0 40.941 0.033755 6279500.0 13049.0 8693.2 8947.1 19363.0 16225.0 16798.0 15570.0 18963.0 15509.0 13162.0 False True 15257.937970502047 9556.20344464268 9160.432796065706 18278.153885693002 13045.827722137039 15917.08330881106 14095.096882961772 18465.241342959325 15735.789784854607 15548.166409665331 0.981333590629512 0.6146193186292489 0.5891648284887943 1.175582599523157 0.839058920415674 1.0237273572603645 0.9065439944223728 1.1876153661103492 1.0120672348266508 1.0 13.924456833367893 -5.75777254237306 24.99988912328788 1.0162805040970004 0.7169972472596705 0.47816535103209534 0.13972004238354016 78.57435938465244 535696.8404843882 0.0377837093959221 0.062320815110684845 1.7467367502444444e-06 5.75777254237306 -0.2992832568373299 RGEFCIAK ddPTM_PC-9_Lapatinib_30min_R1 1 RGEFCIAK 8 1 Q7KZF4;H7C597 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 73.665 0.018561 3420400.0 23054.0 22877.0 18972.0 24107.0 22489.0 18642.0 18027.0 19388.0 19381.0 18583.0 False True 22725.245732414194 22824.02971205869 17412.19539403783 25879.90919859454 21166.241235075166 17844.725116624493 18960.349853211563 20288.837259373777 17198.10768902224 21795.046789708947 1.0426793735145576 1.0472117785420678 0.7989060799933412 1.1874215939198791 0.9711491532594145 0.8187514020410503 0.8699384789650529 0.9308921176050715 0.7890833112201776 1.0 14.411712680429183 -6.5748493709766755 7.4212390961601935 0.8779730290899376 1.0143710369861647 0.28318469869741425 0.10365399489709023 0.2936813641758524 35.00947043781099 0.03333452651463116 0.03339684098507138 2.661648055472818e-07 6.5748493709766755 0.13639800789622714 RGEGDAPFSEPGT(ph)TSTQRPSSPETATK ddPTM_PC-9_AZD4547_30min_R2 1 RGEGDAPFSEPGTTSTQRPSSPETATK 27 2 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 RGEGDAPFS(0.001)EPGT(0.38)T(0.058)S(0.058)T(0.058)QRPS(0.221)S(0.221)PET(0.003)ATK 79.586 1.2913e-05 257970000.0 106180.0 92593.0 123350.0 133820.0 121050.0 141330.0 114060.0 141190.0 109230.0 114300.0 True False 139943.03131879974 122521.87649519696 121714.29840454162 102969.86649839017 104244.29697509584 132492.61275813298 124211.11903650143 119372.32972343286 115003.67480253534 110298.39179021247 1.2687676497130744 1.1108219667267096 1.103500209105879 0.9335572788245077 0.9451116673883014 1.2012198057260337 1.126137172269483 1.082267182557648 1.0426595794911708 1.0 16.75105223025097 -4.69652283389098 1.8834729557597625 1.0569352458915888 1.3671212013302891 0.4150019752079165 0.07701050271306858 1.1902754944032634 3.7269159096091697 0.022794250500850828 0.703084932506358 2.0113014472709952e-05 4.69652283389098 0.3101859554387003 RGEGDAPFSEPGT(ph)TSTQRPSSPETATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGEGDAPFSEPGTTSTQRPSSPETATK 27 2 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 RGEGDAPFS(0.017)EPGT(0.547)T(0.125)S(0.125)T(0.125)QRPS(0.03)S(0.03)PET(0.001)ATK 70.316 0.0016890999999999998 115960000.0 77603.0 82372.0 89553.0 90247.0 87582.0 79447.0 84110.0 73337.0 74696.0 61962.0 True False 90739.65517088455 90549.34778241713 91688.28315164385 85190.75317472158 70420.9358126475 75280.65946154967 76142.49189633354 71411.98145697443 75788.28768905156 73195.2201090779 1.2396937263889822 1.2370937289002963 1.252653971324999 1.1638841040134527 0.9620974663059135 1.0284914691063705 1.040265905107786 0.9756372253619017 1.0354267338237304 1.0 16.159461818358114 -6.081123373152088 3.655433069017077 1.0089718958645513 1.24013569372982 0.9493257050176223 0.024926105311845765 0.04785547131555173 1.211488482283874 0.007562015636893093 0.010328462632546099 8.296150593290853e-07 6.081123373152088 0.23116379786526875 RGEGDAPFSEPGT(ph)TSTQRPSSPETATK ddPTM_PC-9_Lapatinib_30min_R1 2 RGEGDAPFSEPGTTSTQRPSSPETATK 27 2 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 RGEGDAPFS(0.025)EPGT(0.808)T(0.061)S(0.025)T(0.025)QRPS(0.024)S(0.024)PET(0.007)AT(0.001)K;RGEGDAPFS(0.075)EPGT(0.386)T(0.116)S(0.116)T(0.116)QRPS(0.093)S(0.093)PET(0.003)AT(0.002)K 58.332 0.023277000000000003 225262000.0 58243.0 85854.0 85323.0 89196.0 100456.0 92752.0 87036.0 95204.0 88578.0 79119.0 True False 57412.44413954191 85655.21033785418 78308.0722963044 95755.77138913344 94547.3755840948 88785.21317547237 91542.29820958138 99627.52539928952 78601.41287230859 92794.61373055926 0.6187044897481454 0.9230623081913437 0.843885966524756 1.0319108786547921 1.018888616300779 0.9567927448167554 0.9865044373737668 1.0736347875596581 0.8470471475913204 1.0 16.501753446004308 -4.289245073704782 1.1357164155314796 0.9845993859778013 7.822263307284207e-16 0.6936605041012203 0.06978635696521017 2.34411371787322 1.1749994671607806 0.02030138258976727 3.6090665005971423 5.1375365700732455e-05 4.289245073704782 -0.9845993859778005 RGEGDAPFSEPGTT(ph)STQRPSSPETATK ddPTM_PC-9_AZD4547_30min_R2 1 RGEGDAPFSEPGTTSTQRPSSPETATK 27 2 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 RGEGDAPFS(0.014)EPGT(0.059)T(0.203)S(0.203)T(0.203)QRPS(0.158)S(0.158)PET(0.003)ATK 59.358999999999995 0.019783000000000002 211300000.0 40445.0 34764.0 49189.0 58601.0 61780.0 52070.0 48898.0 78428.0 45156.0 51918.0 True False 53305.668691739134 46000.78315292763 48536.72172047832 45091.44482642475 53202.913400424695 48814.054668619334 53249.82727202225 66308.75469614977 47542.853972198915 50100.3666226093 1.0639776170357074 0.9181725854311092 0.968789751302432 0.900022252653055 1.0619266282258157 0.9743252985815581 1.0628630259961345 1.3235183525827923 0.9489522168634944 1.0 15.612533540308956 -7.400126082100578 4.596438291827178 1.1172725482496868 0.9783184418701344 0.17350521486450754 0.1046558222170618 0.3020869848751274 9.967576240912765 0.04355572847534214 0.028496462052344875 3.9799161093886276e-08 7.400126082100578 -0.1389541063795524 RGEGDAPFSEPGTTS(ph)TQRPSSPETATK ddPTM_PC-9_Lapatinib_30min_R1 1 RGEGDAPFSEPGTTSTQRPSSPETATK 27 2 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 RGEGDAPFS(0.003)EPGT(0.196)T(0.196)S(0.238)T(0.238)QRPS(0.052)S(0.052)PET(0.017)AT(0.007)K 50.908 0.0052483 52229000.0 20055.0 24738.0 35202.0 30673.0 39548.0 36064.0 27008.0 28804.0 29602.0 33090.0 True False 19769.012022363426 24680.7206808982 32307.82744364958 32928.79474212843 37221.864394359574 34521.6267892901 28406.342088841084 30142.338994171794 26267.9110371207 38809.562410346545 0.5093850792064857 0.6359443175354735 0.8324707993882555 0.8484711678519129 0.9590900304620881 0.8895134251780873 0.731941828884626 0.7766729929976204 0.6768412062826488 1.0 15.244124545937895 -5.076833345587739 2.4858527742875256 0.8353270828999447 0.5089252299322595 0.586190299595778 0.09243803166646243 0.2444733068890075 2.6853761304579757 0.02600705470482252 0.1274838233240418 8.378507339068324e-06 5.076833345587739 -0.3264018529676852 RGEGDAPFSEPGTTST(ph)QRPSSPETATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGEGDAPFSEPGTTSTQRPSSPETATK 27 2 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 RGEGDAPFS(0.026)EPGT(0.021)T(0.021)S(0.084)T(0.28)QRPS(0.28)S(0.28)PET(0.008)ATK 53.998000000000005 0.042567 94446000.0 23343.0 21775.0 18416.0 17935.0 25356.0 17769.0 22300.0 18062.0 18910.0 15437.0 True False 27294.508854734413 23936.67809403839 18855.107283068923 16930.160096054522 20387.673819568998 16837.16235946324 20187.58256198122 17587.8916382709 19186.522975794735 18235.605900775237 1.4967700554207557 1.312634097505956 1.0339720756011375 0.9284122605070546 1.1180146100164552 0.9233124718245558 1.1070420512390542 0.9644807929043475 1.052146173820255 1.0 14.154470515363947 -5.091184114488733 2.4583361387859965 1.0127023598814993 1.4953725932974136 0.8649513610952451 0.06346942998912833 0.10116599532994182 1.0882093277456653 0.015985212021320108 0.0764926183019677 8.106173324736606e-06 5.091184114488733 0.4826702334159143 RGEGDAPFSEPGTTST(ph)QRPSSPETATK ddPTM_PC-9_Lapatinib_30min_R1 1 RGEGDAPFSEPGTTSTQRPSSPETATK 27 2 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 RGEGDAPFS(0.003)EPGT(0.016)T(0.065)S(0.065)T(0.27)QRPS(0.27)S(0.27)PET(0.039)AT(0.001)K 63.115 0.0069966 33056000.0 21303.0 29479.0 32487.0 25419.0 32257.0 34489.0 32120.0 30064.0 34054.0 28635.0 True False 20999.215313508248 29410.74318668435 29816.0442634465 27288.39805529826 30359.70667970205 33013.98586778579 33783.01643563299 31460.883194027916 30218.479915482345 33584.52159626087 0.6252646849031249 0.8757231542627897 0.8877912456780706 0.812529009147369 0.903979131954708 0.98301194415291 1.0059103071872912 0.9367673469414735 0.8997740172915465 1.0 15.035508857750449 -3.8816521295575903 0.6213509525520505 0.9526001013561433 4.6621301510173044e-30 0.7295595505064129 0.05524791964757307 5.610386145642958 0.7124862384588779 0.02674921260040587 4.909263155599405 0.00013132513939057605 3.8816521295575903 -0.9526001013561433 RGEGDAPFSEPGTTSTQRPS(ph)SPETATK ddPTM_PC-9_AZD4547_30min_R2 1 RGEGDAPFSEPGTTSTQRPSSPETATK 27 2 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 RGEGDAPFSEPGT(0.021)T(0.093)S(0.093)T(0.122)QRPS(0.318)S(0.318)PET(0.027)AT(0.008)K 86.039 2.5539e-07 53199000.0 60979.0 64195.0 80453.0 100590.0 70266.0 69881.0 81416.0 93137.0 74321.0 69286.0 True False 80369.05355800611 84944.77834835433 79386.14065294364 77400.52960000784 60510.778779447086 65511.33002300344 88661.866276309 78744.8167253442 78249.45633067138 66860.31822901723 1.2020441374914983 1.270481215141577 1.1873431469623223 1.1576452468396445 0.9050327665533836 0.9798237842453413 1.3260760436798213 1.177751150624484 1.1703422658361098 1.0 16.028862601186376 -5.758708789683924 3.1345941385923393 1.10360371610171 1.2315036213581176 0.19539566216739424 0.11374854775003539 0.4637166386080738 9.395098339347513 0.036108061114818436 0.06286520535546046 1.7429752101956502e-06 5.758708789683924 0.1278999052564076 RGEGDAPFSEPGTTSTQRPS(ph)SPETATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RGEGDAPFSEPGTTSTQRPSSPETATK 27 2 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 RGEGDAPFS(0.012)EPGT(0.057)T(0.057)S(0.057)T(0.068)QRPS(0.368)S(0.368)PET(0.009)AT(0.005)K;RGEGDAPFS(0.001)EPGT(0.021)T(0.086)S(0.086)T(0.086)QRPS(0.358)S(0.358)PET(0.005)ATK;RGEGDAPFS(0.003)EPGT(0.01)T(0.009)S(0.009)T(0.03)QRPS(0.466)S(0.466)PET(0.006)ATK 65.023 0.0011462999999999998 358495000.0 96266.0 109172.0 108259.0 110649.0 128651.0 95943.0 124234.0 106857.0 87577.0 80495.0 True False 112561.93245983226 120009.8746673875 110840.30513454397 104449.69525889786 103442.76007893078 90911.58018200137 112465.65614372976 104052.1169743502 88857.6479455937 95088.10630193076 1.1837645825274647 1.262091331236772 1.1656589813934843 1.0984517340921849 1.087862237475544 0.95607730259484 1.1827520866449956 1.0942705772681627 0.9344769961392053 1.0 16.536977278444887 -5.77826513176815 1.7188165157996107 1.0496554060749543 1.2251721759243006 0.5220441212110487 0.0700353843569631 0.3070543025541508 1.8473142363767618 0.022419933291403432 0.04660373702230721 1.6662296879978974e-06 5.77826513176815 0.17551676984934628 RGEIIAK ddPTM_PC-9_AZD4547_30min_R2 1 RGEIIAK 7 1 A0A087X0X3;P52272-2;P52272;M0R2T0;M0R019 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 87.181 0.011462 5480800.0 40780.0 41909.0 52967.0 76447.0 67240.0 56689.0 51762.0 65685.0 54285.0 64063.0 False True 53747.191723306314 55455.26467483728 52264.622971976976 58823.325244376254 57904.88664688499 53144.22786843409 56368.71772371911 55534.892541140915 57154.394274976024 61820.1738692596 0.8694118498756339 0.8970415513893062 0.8454298928778301 0.9515231284981303 0.9366665122835977 0.8596583371121889 0.9118175216221569 0.8983296077197856 0.9245265857040292 1.0 15.915790091331575 -14.522878745280043 0.18604616853876133 1.4263484298237994 0.8803061635772194 0.5191466092178207 0.030543917830490975 116.3929417807726 1.1285836881751117 18.331914924734505 0.09014136579407483 3.0000000000020383e-15 14.522878745280043 -0.54604226624658 RGEIIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGEIIAK 7 1 A0A087X0X3;P52272-2;P52272;M0R2T0;M0R019 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 98.523 0.0076789 3786800.0 39182.0 40380.0 37684.0 41331.0 50933.0 46077.0 39744.0 39700.0 41317.0 36356.0 False True 45814.73872022466 44388.659537876934 38582.52947736587 39015.35806690992 40953.04427559979 43660.64100607733 35979.16059835793 38657.917065627 41921.18296091545 42947.05500606233 1.066772534548819 1.0335670171473017 0.8983742766976601 0.9084524669130999 0.9535704897534634 1.016615481548485 0.8377561766058039 0.9001296377637563 0.9761130991402771 1.0 15.390271584863845 -5.143252726776473 4.7436678355539925 0.9319871663527596 1.0586596627841665 0.4456870846519251 0.050984356583203265 0.19163690570727027 6.505745624550921 0.013285823903975078 0.03842107986230659 7.190304345155383e-06 5.143252726776473 0.12667249643140688 RGEIIAK ddPTM_PC-9_Lapatinib_30min_R1 2 RGEIIAK 7 1 A0A087X0X3;P52272-2;P52272;M0R2T0;M0R019 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 ; 104.44 0.006549200000000001 12223300.0 121683.0 112912.0 120971.0 110103.0 129235.0 111582.0 113060.0 115213.0 130270.0 118014.0 False True 119947.7781060708 112650.55920129278 111025.23134156369 118200.3419128409 121633.65138578591 106809.89797034614 118913.69359317144 120566.21658573509 115597.62079608525 138412.5626562296 0.8665960358235753 0.8138752512015763 0.802132618679369 0.8539711977330477 0.87877609554765 0.7716777720215044 0.8591250050655675 0.871064116377797 0.8351671161756536 1.0 17.07861536581698 -12.908867815855457 0.32709251393842526 1.4802543039145626 0.8308357830158299 0.6921400799534502 0.032268535730986 60.05307887316707 1.4095576782915729 19.64971663997661 0.02807190456967408 1.2334802046004523e-13 12.908867815855457 -0.6494185208987326 RGEPHVTR ddPTM_PC-9_Lapatinib_30min_R1 2 RGEPHVTR 8 1 H0YBN9;P67775-2;P67775;P62714 H0YBN9 PPP2CB;PPP2CA Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform;Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform 0 ; 101.46 0.0028975999999999997 812400.0 4703.5 4144.0 5450.9 4225.3 5877.8 4564.0 3624.7 5013.6 5759.8 3134.9700000000003 False True 4636.427227483738 4134.404822606603 5002.748043082484 4536.0426571876005 5532.079360199423 4368.8083592036355 3812.3692302066906 5246.550159046649 5111.070670617118 3676.8453874150514 1.2609796548294094 1.1244434799346381 1.3606087599455978 1.2336778350031723 1.5045722017940668 1.1881947427425166 1.0368587276624426 1.4269161757533553 1.3900695112476231 1.0 11.844252796667167 RGES(ph)LDNLDSPR ddPTM_PC-9_AZD4547_30min_R2 3 RGESLDNLDSPR 12 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 RGES(1)LDNLDSPR;RGES(1)LDNLDSPR;RGES(1)LDNLDSPR 120.77 0.00021899 115984000.0 68318.0 77854.0 95319.0 142622.0 147171.0 117531.0 112761.0 159937.0 108906.0 110138.0 True False 90041.70289732295 103018.78298205131 94055.0077796718 109742.70138793433 126738.84700637564 110181.76799034966 122796.51055299825 135222.4116366364 114662.54882399435 106282.10214339796 0.8471953516297303 0.9692956848280653 0.884956223887733 1.032560508069997 1.1924759150451976 1.0366916514474864 1.155382779193798 1.2722971122098392 1.0788509684282432 1.0 16.697539142585462 -5.960522847568865 3.6211031469481156 1.1332029995671413 0.9081696122783037 0.6115576488937524 0.0786940119475492 0.14746278270309182 4.081110616272022 0.022786688228589633 0.034132161095554475 1.0951589392133813e-06 5.960522847568865 -0.2250333872888376 RGES(ph)LDNLDSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RGESLDNLDSPR 12 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 RGES(0.999)LDNLDS(0.001)PR;RGES(1)LDNLDSPR 113.43 0.00038255 49326000.0 116483.0 103771.0 130844.0 166244.0 178887.0 223744.0 171962.0 216791.0 193887.0 169011.0 True False 136201.27125588068 114072.69908135296 133963.8171886332 156929.88765032007 143835.37650107447 212010.47076119884 155672.51446293332 211100.46595905157 196722.23057683307 199651.35640965978 0.6821955718468178 0.5713594995432435 0.670988765604758 0.7860196418015786 0.7204327538148158 1.0619034830205696 0.7797217973491383 1.057345513475499 0.9853287957292085 1.0 17.60712334795469 -6.40951568853896 0.783727761227088 0.9976038987116249 0.6079214157085335 0.708656838018509 0.09175347089532991 0.35113935053990764 0.47564610085041675 0.051962540361311885 0.07482668399683036 3.8947923782522275e-07 6.40951568853896 -0.3896824830030914 RGES(ph)LDNLDSPR ddPTM_PC-9_Lapatinib_30min_R1 4 RGESLDNLDSPR 12 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 RGES(0.996)LDNLDS(0.004)PR;RGES(1)LDNLDSPR;RGES(0.98)LDNLDS(0.02)PR;RGES(1)LDNLDSPR 133.87 2.5521999999999997e-05 173402000.0 91641.0 71802.2 73956.6 82470.1 94116.0 91241.0 83177.0 87113.0 93771.0 86637.9 True False 90334.18253509901 71635.94641741418 67876.17382873192 88535.22626618875 88580.28191917541 87338.8351231594 87483.49807181339 91160.58800164147 83209.5225275942 101613.14557725491 0.8890009459102841 0.7049869976021013 0.6679861492637948 0.8712969740600814 0.8717403778414594 0.8595229940673083 0.8609466577855425 0.8971338057075842 0.8188854114779006 1.0 16.632727528439787 -5.832334159446912 10.400468701683458 0.8763614107397574 0.7492037909062323 0.4197023909549913 0.06905001854794678 0.3849488221569161 54.0096555604633 0.01884241878890476 0.027986077689568848 1.4711800959077562e-06 5.832334159446912 -0.12715761983352503 RGESLDNLDS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 RGESLDNLDSPR 12 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 RGES(0.001)LDNLDS(0.999)PR;RGESLDNLDS(1)PR 120.54 0.00022371 9855500.0 34172.0 37336.0 40279.0 71348.0 53555.0 47035.0 37463.0 53297.0 48774.0 49285.0 True False 45037.98517824477 49404.13185472634 39744.87414216894 54899.8209156116 46119.81267659022 44093.89401456713 40797.134424552554 45061.173293220476 51352.094065905534 47559.5471511865 0.9469809507452633 1.0387847406888908 0.8356865555473943 1.1543385966458255 0.9697277505603759 0.9271302326407261 0.8578116670216184 0.9474685103702948 1.0797431250273042 1.0 15.537447357756486 -6.516279326558622 24.82019263448939 0.9521443670486809 0.9953693753544111 0.02016840992805824 0.09116687081228823 1036.8060182321371 3899409.012702589 0.02952095460714968 0.030587162877880974 3.045935295624657e-07 6.516279326558622 0.04322500830573017 RGESLDNLDS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGESLDNLDSPR 12 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 RGESLDNLDS(1)PR 67.648 0.016681 3103400.0 19377.0 23691.0 28898.0 32636.0 35566.0 27375.0 34562.0 25187.0 35401.0 25042.0 True False 22657.143386804983 26042.88591163551 29587.037916275298 30807.510727339573 28597.097612667258 25939.406809066717 31288.037152789006 24525.867937832438 35918.67265288787 29581.91636763706 0.7659119546288808 0.8803650712814101 1.0001731310634034 1.0414305261522316 0.9667087573796536 0.8768670185764136 1.0576744509702711 0.8290831342037058 1.2142104725907241 1.0 14.852427895290434 -4.964031942218418 2.486069662899023 0.9903253863940199 0.755123365386095 0.360011184767262 0.0986330570969869 0.3925331943496413 4.0511798987173515 0.024464390683561207 0.1675412673869852 1.0863457203029536e-05 4.964031942218418 -0.23520202100792487 RGESLDNLDS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 RGESLDNLDSPR 12 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 RGESLDNLDS(1)PR;RGESLDNLDS(1)PR 126.07 0.00012584 7853300.0 40758.0 36271.0 48655.0 35980.0 42021.0 41825.0 41302.0 33643.0 52980.0 39243.0 True False 40176.783445898196 36187.01672798359 44654.77371373135 38626.08922576147 39549.40739646462 40036.242248837 43440.415467761944 35206.17659980982 47012.83449586703 46026.10026198937 0.8729130475361644 0.7862281731886943 0.9702054586321204 0.8392214201484457 0.8592821718838187 0.8698595366746922 0.9438213366001201 0.764917653231743 1.021438580028744 1.0 15.490164589414533 -8.28713213475037 24.918781293152673 1.0107193709059679 0.8662654811996595 0.5009826322423614 0.058790177992185846 666.6507394274576 646561.588232546 0.05312583070184038 0.013736392225608714 5.162592727133985e-09 8.28713213475037 -0.14445388970630835 RGESMQPNR ddPTM_PC-9_Lapatinib_30min_R1 2 RGESMQPNR 9 1 K7ER90;K7EL20;K7ENA8;O75821;K7EP16 K7ER90 EIF3G Eukaryotic translation initiation factor 3 subunit G 0 ; 88.49600000000001 0.0063743 1727030.0 1775.53 2238.97 2084.8199999999997 4144.26 2554.4700000000003 4042.8999999999996 2101.12 2854.81 2516.1000000000004 3171.2999999999997 False True 1750.210616607676 2233.7858025269074 1913.4141472379274 4449.042705246087 2404.2210968812497 3869.994591460208 2209.905712740883 2987.454894596292 2232.710322292394 3719.4549795083667 0.4705556664215941 0.6005680441982838 0.5144340119129067 1.1961544714903787 0.6463906970582655 1.0404735674396413 0.5941477245768372 0.8031969498367663 0.6002788942447452 1.0 11.860875519982834 RGEVPAELR ddPTM_PC-9_AZD4547_30min_R2 2 RGEVPAELR 9 1 Q9UNZ2-4;Q9UNZ2;Q9UNZ2-5;F2Z2K0;Q9UNZ2-6 Q9UNZ2-4 NSFL1C NSFL1 cofactor p47 0 ; 120.06 0.0010756 5154100.0 23525.0 22120.0 31650.0 29157.0 29404.0 31023.0 27079.0 38236.0 31798.0 27036.0 False True 31005.460649602264 29269.857419823933 31230.300320257353 22435.304121159457 25321.762149985236 29083.12690579178 29488.978541026027 32327.504775870653 33478.77736309637 26089.477869117945 1.1884277947280562 1.121902767340185 1.19704581582388 0.859936876993467 0.9705737415296666 1.1147454560682264 1.1303015985587073 1.2391012552281333 1.283229106042215 1.0 14.67118045121835 -7.360172807583868 2.611311559359323 1.1931111902547187 1.0668262633298224 0.11745347960260344 0.11697744581076798 0.5354707804353195 7.112275260974981 0.06003139384837718 0.03728527957513784 4.363421753234404e-08 7.360172807583868 -0.12628492692489623 RGEVPAELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGEVPAELR 9 1 Q9UNZ2-4;Q9UNZ2;Q9UNZ2-5;F2Z2K0;Q9UNZ2-6 Q9UNZ2-4 NSFL1C NSFL1 cofactor p47 0 103.88 0.0042117 0.0 9830.2 11710.0 10330.0 10921.0 13562.0 10244.0 11074.0 8145.9 8727.8 10848.0 False True 11494.258704699923 12872.491411306059 10576.306376743156 10309.13177635971 10904.623455631598 9706.786606468651 10024.990551182953 7932.078756294487 8855.427563624606 12814.65652727925 0.8969619029766014 1.0045131825346776 0.8253289000941072 0.8044797575661982 0.8509493354284087 0.7574753631363659 0.782306613512599 0.6189848896385981 0.6910390102749597 1.0 13.645507189975142 -5.6907621503221195 0.8447874726798825 0.7497789411095267 0.9686043339556204 0.25444850585694745 0.10064356607853306 1.017714493289818 1.2548426992490467 0.043280446357502514 0.1634512840731058 2.0381580083057124e-06 5.6907621503221195 0.2188253928460937 RGEVPAELR ddPTM_PC-9_Lapatinib_30min_R1 2 RGEVPAELR 9 1 Q9UNZ2-4;Q9UNZ2;Q9UNZ2-5;F2Z2K0;Q9UNZ2-6 Q9UNZ2-4 NSFL1C NSFL1 cofactor p47 0 ; 112.36 0.0013753 6218400.0 17728.1 22945.0 29112.0 26827.0 31402.0 27100.0 26398.0 27054.0 25846.0 26638.0 False True 17475.294043064627 22891.8722622366 26718.523735569746 28799.947072248564 29554.996098707386 25940.99617318549 27764.75927359401 28311.02760548268 22934.951309554144 31242.342807096124 0.5593464661393907 0.7327194507652971 0.8552023099081137 0.9218241810504424 0.9459916716615283 0.8303153298507905 0.8886900526322806 0.9061749235736685 0.7340983181435706 1.0 14.931215022192202 -4.9051990304381246 1.7951711687466765 0.8858929509035389 0.498739105212137 0.7047571644687012 0.06699665178909624 0.3568025216497114 1.4467504369023485 0.018067865979496764 0.2186416000894456 1.2439444006594914e-05 4.9051990304381246 -0.38715384569140193 RGFEGS(ph)CSQK ddPTM_PC-9_Lapatinib_30min_R1 1 RGFEGSCSQK 10 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 RGFEGS(0.89)CS(0.11)QK 69.26100000000001 0.038449000000000004 0.0 24032.0 28769.0 21790.0 28810.0 28556.0 26495.0 29668.0 26540.0 25531.0 21861.0 True False 23689.299273070956 28702.387148062087 19998.510311832408 30928.78350734265 26876.392223256084 25361.870612861607 31204.06387336112 27773.14528903345 22655.42992665121 25639.64472204853 0.9239324308070307 1.1194533878770865 0.7799839088501451 1.206287522414294 1.0482357503239514 0.9891662262797247 1.2170240349129147 1.0832110035109122 0.8836093546635192 1.0 14.646088650816171 -5.77494487934574 24.99981999628976 1.0675099024827375 0.958956177639663 0.1658069486526791 0.12073261037954044 433.99903030741666 803368.0103405751 0.03326027235693655 0.04964399466390509 1.6790171054454295e-06 5.77494487934574 -0.10855372484307446 RGFEGS(ph)FEELCR ddPTM_PC-9_Lapatinib_30min_R1 1 RGFEGSFEELCR 12 1 H0Y9U7;B7Z3Z9;E7EPM6;P33121-2;P33121-3;P33121 H0Y9U7 ACSL1 Long-chain-fatty-acid--CoA ligase 1 1 RGFEGS(1)FEELCR 80.014 0.021676 16117000.0 15524.0 13340.0 13971.0 13864.0 11613.0 10729.0 9333.0 8387.4 11887.0 9037.4 True False 15302.624913247071 13309.11204960715 12822.358309619585 14883.604808948226 10929.946172036456 10270.145680520556 9816.217073280277 8777.10922370908 10548.16088434072 10599.502548421448 1.4437116122516567 1.2556355346684867 1.209713215412093 1.4041795585175643 1.0311753897982903 0.968927139137304 0.9261016758510217 0.8280680327791636 0.995156219469151 1.0 13.371708937944913 -6.413384271768134 3.7717269601798975 0.9359829881437881 1.3139962965355076 0.8436971869510076 0.0784378099158832 0.09229011101458057 2.35034692200703 0.025717961055433072 0.02908582659530011 3.860252636257131e-07 6.413384271768134 0.37801330839171954 RGFEGSCS(ph)QK ddPTM_PC-9_AZD4547_30min_R2 2 RGFEGSCSQK 10 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 RGFEGS(0.133)CS(0.867)QK;RGFEGS(0.002)CS(0.998)QK 83.617 0.0063311999999999995 22222900.0 45648.0 61443.0 61783.0 55521.0 63156.0 72720.0 72314.0 85768.0 62386.0 60947.0 True False 60163.11446261612 81303.24816664742 60963.717051704894 42721.49124089909 54387.87955191359 68172.80690420579 78749.80590921943 72514.52635257017 65683.59659645676 58813.26408082301 1.022951461764443 1.3823964617049305 1.0365640813257135 0.7263921142378681 0.9247553320144258 1.1591399996184637 1.3389803667587468 1.2329621129838748 1.1168160384057637 1.0 15.843853940488666 -6.92411499234387 7.402881319751865 1.199608193986051 1.0242967795605995 0.15478274091031652 0.17155904872694108 0.4372249423295607 36.10844523869549 0.06662986911049414 0.05871454961272425 1.1909266331315913e-07 6.92411499234387 -0.1753114144254515 RGFEGSCS(ph)QK ddPTM_PC-9_Lapatinib_30min_R1 1 RGFEGSCSQK 10 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 RGFEGS(0.246)CS(0.754)QK 80.69 0.025428 10529000.0 26992.0 32256.0 24477.0 23389.0 28446.0 27632.0 28663.0 26186.0 24712.0 24697.0 True False 26607.089130273445 32181.31321380272 22464.59554395237 25109.105083416758 26772.862206987767 26450.243773338065 30147.02989086387 27402.697156692902 21928.674331103528 28965.84354331604 0.9185677292803411 1.1110090118963118 0.7755546808211683 0.8668521959620528 0.9242907829337388 0.9131528910519694 1.040778593096433 0.9460348398179538 0.7570528473755993 1.0 14.822065059336945 -5.250219081347697 24.99603879155865 0.905794989687022 1.0147883481613758 0.18436213766231235 0.0939312405732484 1285.7307066477006 2864276.5276975366 0.023927268671407324 0.06198239184905379 5.62057721709779e-06 5.250219081347697 0.10899335847435376 RGFS(ph)DSGGGPPAK ddPTM_PC-9_AZD4547_30min_R2 1 RGFSDSGGGPPAK 13 1 Q9H307;G3V5F0;G3V579 Q9H307 PNN Pinin 1 RGFS(0.989)DS(0.011)GGGPPAK 75.968 0.028852 0.0 9211.7 8627.9 12754.0 19733.0 16232.0 14287.0 10673.0 14239.0 13188.0 8236.5 True False 12140.82898473713 11416.699947219655 12584.87362668444 15183.861721810885 13978.466984715014 13393.631631468494 11622.876323659328 12038.68972966896 13885.090756164393 7948.14264199549 1.5275051709048102 1.4363984721282426 1.5833728952208181 1.9103660321323535 1.7587086209119078 1.685127234720317 1.462338667935789 1.5146544635548316 1.7469604386312765 1.0 12.956402048927186 -10.140078423037576 6.876041407006315 1.0000492366453224 1.6243312463244517 0.6336932523073664 0.1425655800270722 6.731464759551752e-10 0.0 0.15268962306978462 0.0370326731677923 7.243051563422286e-11 10.140078423037576 0.6242820096791293 RGFS(ph)DSGGGPPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RGFSDSGGGPPAK 13 1 Q9H307;G3V5F0;G3V579 Q9H307 PNN Pinin 1 RGFS(0.989)DS(0.011)GGGPPAK;RGFS(0.984)DS(0.016)GGGPPAK 95.195 0.0052545000000000005 15460300.0 35135.0 26620.0 23920.0 29123.0 38968.0 42540.0 38635.0 60392.0 47676.0 31635.0 True False 41082.66155211817 29262.65767454888 24490.34351710515 27491.332728039906 31332.500134128608 40309.12751260996 34975.2131068226 58806.773990613234 48373.17130586936 37370.17507747779 1.099343566545874 0.7830484501043952 0.6553446288739749 0.7356490214734998 0.8384360006119436 1.0786443314498522 0.9359124765755089 1.5736285384987352 1.2944325576634197 1.0 15.189599702241008 -7.259713843372268 1.5394372682032826 1.3016713971764633 0.8107547557064307 0.473753595324249 0.19161997849516205 0.31327791321834797 1.4489669894073047 0.10994332019755082 0.06592892365287474 5.4990308564888645e-08 7.259713843372268 -0.49091664147003256 RGGADVNIR ddPTM_PC-9_AZD4547_30min_R2 2 RGGADVNIR 9 1 P08621;P08621-4;P08621-2 P08621 SNRNP70 U1 small nuclear ribonucleoprotein 70 kDa 0 ; 169.41 0.00077905 4646000.0 23757.0 17703.0 28927.0 45741.0 36110.0 30085.0 21540.0 28852.0 26412.0 32811.0 False True 31311.23182370249 23425.148548966685 28543.40907943397 35196.11914140533 31096.749803971103 28203.78019407361 23457.01827149083 24393.586353002935 27808.084398833333 31662.296876891123 0.9889122051203789 0.7398436266341637 0.9014952133894781 1.1116097887103504 0.9821381539337158 0.8907686104938985 0.7408501778217816 0.7704300938068301 0.8782712292464542 1.0 14.950478296196524 -7.0051985206069345 22.459393770013893 0.8264787997967222 0.9398926619735533 0.14025891148782565 0.10882744619902503 108.72635669663293 469740.8694944731 0.041126849354017 0.03513749509941347 9.881013198318114e-08 7.0051985206069345 0.11341386217683103 RGGADVNIR ddPTM_PC-9_Lapatinib_30min_R1 2 RGGADVNIR 9 1 P08621;P08621-4;P08621-2 P08621 SNRNP70 U1 small nuclear ribonucleoprotein 70 kDa 0 ; 131.52 0.00077905 4054000.0 34670.0 28141.0 32815.0 24410.0 30794.0 24958.0 18515.6 22465.0 30770.0 18671.6 False True 34175.599442300656 28075.841243477873 30117.077369563132 26205.192829372925 28982.75746333338 23890.604519939618 19474.247170473398 23508.80591251454 27304.358577535433 21898.961181656883 1.5606036815539448 1.2820626974303648 1.3752742479305342 1.1966409096758 1.3234763614088718 1.090946932220282 0.8892772131486087 1.073512378852295 1.2468335073540495 1.0 14.418574814050865 -5.097781987603222 0.43373360389672977 1.0359200763447722 1.735076808586853 0.6306604779164299 0.11357173436127642 2.846548240958622 0.5133887541885688 0.09415789558951476 1.0007201979905114 7.983953748553512e-06 5.097781987603222 0.6991567322420809 RGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDR ddPTM_PC-9_AZD4547_30min_R2 1 RGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDR 32 1 P31942;P31942-3;P31942-4;P31942-5 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 0 124.16 3.7712e-17 5597700.0 12751.0 10987.0 20647.0 29778.0 22809.0 17842.0 15074.0 17898.0 12241.0 14788.0 False True 16805.552762723855 14538.332887504765 20373.207289489867 22913.14216551382 19642.364061998807 16726.336919483507 16415.556797792626 15132.275355124317 12888.034269503201 14270.276621116893 1.17766131722039 1.0187842375803149 1.4276672996893396 1.6056550811080545 1.3764529296462549 1.1721102094637872 1.1503320666889658 1.060405187432166 0.9031383631647144 1.0 13.800725680449009 -7.493003940867007 1.4237876523731767 0.9656306601305193 1.3175402039359188 0.47298481717636776 0.15063562586820556 0.4386450193823079 1.702170804329465 0.11951348281446118 0.05763955015147408 3.213631377433218e-08 7.493003940867007 0.3519095438053994 RGGGAAGAGGGGSGAGGGS(ph)GGSGGR ddPTM_PC-9_AZD4547_30min_R2 1 RGGGAAGAGGGGSGAGGGSGGSGGR 25 1 C9JRT7;Q6PID8 C9JRT7 KLHDC10 Kelch domain-containing protein 10 1 RGGGAAGAGGGGS(0.007)GAGGGS(0.759)GGS(0.234)GGR 56.211000000000006 0.042643 0.0 0.0 0.0 0.0 404.96 0.0 0.0 473.25 0.0 0.0 0.0 True False 0.0 0.0 0.0 311.60272856963115 0.0 0.0 515.3683331932704 0.0 0.0 0.0 0.0 RGGGSGGGEES(ph)EGEEVDED ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGGGSGGGEESEGEEVDED 19 1 Q96QR8 Q96QR8 PURB Transcriptional activator protein Pur-beta 1 RGGGS(0.006)GGGEES(0.994)EGEEVDED 93.34200000000001 0.0012109999999999998 6946900.0 3796.9 3949.5 4279.9 3637.0 6125.9 3986.4 4418.9 4552.0 5588.1 3109.6 True False 4439.640177806672 4341.580258663813 4381.949047611139 3433.2306813130945 4925.573870141097 3777.346166343872 4000.3098019344725 4432.514823242672 5669.815390853441 3673.3458644199463 1.2086093555221842 1.1819143687819842 1.1929040197534155 0.9346331132517063 1.3408957533376424 1.0283121453199584 1.0890098426836148 1.2066696104431769 1.543501646760604 1.0 11.842879024290633 -8.006870932445121 24.75218044253742 1.3061957449913326 1.1393990780588028 0.09232059122412528 0.160293389968715 463.4484158619435 1669539.8186358265 0.08647792774200436 0.03899888976584844 9.843035865239355e-09 8.006870932445121 -0.1667966669325298 RGGIPAS(ph)PIDPFQSR ddPTM_PC-9_AZD4547_30min_R2 2 RGGIPASPIDPFQSR 15 1 Q96LD4-2;Q96LD4 Q96LD4-2 TRIM47 Tripartite motif-containing protein 47 1 RGGIPAS(1)PIDPFQSR;RGGIPAS(1)PIDPFQSR 72.64399999999999 0.0088106 27436500.0 44258.0 41027.0 68178.0 103336.0 82116.0 61339.0 43495.0 86052.0 54567.0 76847.0 True False 58331.12337641221 54288.17542328737 67273.91517328614 79513.48172528503 70715.61082533609 57503.462633348274 47365.97073902017 72754.64067824099 57451.30021926161 74156.60992040651 0.7865937161774244 0.7320746657857709 0.9071870362667915 1.0722372801376456 0.9535982146599783 0.7754327320931698 0.6387289115543285 0.9810944804020805 0.7747293232649797 1.0 16.178287672018705 -12.084184695767878 2.073856855467295 3.1781123595645067 0.85074654213704 0.11957735799092939 0.12426327057535294 7053565.6495438265 286418.4177094878 72773976.40904295 0.03328212280498662 8.237877019496724e-13 12.084184695767878 -2.3273658174274665 RGGIPAS(ph)PIDPFQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RGGIPASPIDPFQSR 15 1 Q96LD4-2;Q96LD4 Q96LD4-2 TRIM47 Tripartite motif-containing protein 47 1 RGGIPAS(1)PIDPFQSR;RGGIPAS(1)PIDPFQSR;RGGIPAS(1)PIDPFQSR 94.45 0.0044515 22247800.0 44767.5 32830.5 40933.2 54175.5 69195.0 78238.0 67925.0 81812.0 71076.0 60197.0 True False 52345.75355157109 36089.69507078425 41909.202728025484 51140.22237434082 55636.736470463606 74135.06154987257 61490.65226558627 79664.52168697926 72115.35203741863 71110.23958081019 0.7361211811427664 0.5075175570147202 0.5893553864405079 0.7191681911889033 0.7824011956426841 1.042537080269923 0.8647228954376937 1.1202960664539447 1.0141345671528252 1.0 16.117769696480053 -6.462152208309299 1.3841308495234657 1.0194233983355352 0.6011904648931296 0.8121082319305263 0.08429090130823362 0.16322136439285798 0.6402629212456232 0.03368232895810253 0.03952829440039689 3.4502279711237685e-07 6.462152208309299 -0.41823293344240564 RGGIPAS(ph)PIDPFQSR ddPTM_PC-9_Lapatinib_30min_R1 4 RGGIPASPIDPFQSR 15 1 Q96LD4-2;Q96LD4 Q96LD4-2 TRIM47 Tripartite motif-containing protein 47 1 RGGIPAS(0.999)PIDPFQS(0.001)R;RGGIPAS(1)PIDPFQSR;RGGIPAS(1)PIDPFQSR;RGGIPAS(1)PIDPFQSR 82.609 0.0034935 40200200.0 101480.0 57961.0 81290.0 68486.0 89235.0 107149.0 90357.0 95192.0 124426.0 82600.0 True False 100032.87659084724 57826.79486561321 74606.64998847448 73522.68890259859 83986.3727427602 102566.48704651848 95035.24333980346 99614.96783548132 110411.83361613333 96877.29994241855 1.0325729211105623 0.5969075820649833 0.770114877611358 0.7589258675282924 0.8669355235197471 1.058725698460645 0.9809856735921628 1.0282591266962433 1.139707998486326 1.0 16.563871035932166 -6.609348455277571 3.1066819560194308 1.0406059029778572 0.7758347342431261 0.5549229513409835 0.10706179333739749 0.18172764136148042 3.5300536333449806 0.03621425822448483 0.036581878324455044 2.458394325033099e-07 6.609348455277571 -0.26477116873473105 RGGRGIS(ph)FIFCCFR ddPTM_PC-9_AZD4547_30min_R2 1 RGGRGISFIFCCFR 14 2 G3V275;Q9Y4D1-3;Q9Y4D1-2;Q9Y4D1 G3V275 DAAM1 Disheveled-associated activator of morphogenesis 1 1 RGGRGIS(1)FIFCCFR 44.82899999999999 0.043532 5564400.0 11976.0 8511.6 20618.0 23726.0 22364.0 17913.0 16857.0 24090.0 17543.0 19394.0 True False 15784.118883725252 11262.808246590113 20344.591848438115 18256.337263045894 19259.144630739673 16792.897278259625 18357.240343663943 20367.44403312911 18470.287165255668 18715.02196307418 0.8433930195149238 0.6018057723262246 1.087072827837401 0.9754910947508746 1.0290741132304881 0.8972950879455541 0.9808826503053985 1.0882938889046059 0.9869230825215493 1.0 14.19190912086772 -5.266102504739138 24.997276592022107 1.0037905410578065 0.7225993909988431 0.692637221778287 0.07540824698187176 184.33138451649265 988137.0634858875 0.018842970531057907 0.04141884764152706 5.4187297925793985e-06 5.266102504739138 -0.28119115005896345 RGILT(ph)LK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGILTLK 7 1 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;Q6S8J3;C9JTX5;A5A3E0;P0CG38;P0CG39;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;POTEE;POTEF;POTEI;POTEJ;ACTG1;ACTA1;ACTC1;ACTG2;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;POTE ankyrin domain family member J;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle 1 RGILT(1)LK 77.192 0.025599 1840200.0 11389.0 9479.8 10116.0 14739.0 14473.0 12402.0 15679.0 15761.0 14594.0 10276.0 True False 13316.932756996539 10420.891894184391 10357.203805143641 13913.221614482733 11637.119545299818 11751.61728752677 14193.771613870109 15347.290450159884 14807.409640864542 12138.95745522876 1.0970408954897832 0.8584667944194561 0.8532202080239072 1.1461628122347296 0.9586588953969207 0.968091150403106 1.1692743521196094 1.264300538721236 1.2198254829937119 1.0 13.567356901739615 -7.28162835368887 5.949660028375509 1.1868430619602934 0.9752136644550454 0.40459358719736216 0.10727781582729452 0.16068530155048236 21.467867765616386 0.04445149591755327 0.03084102000855189 5.228434194351521e-08 7.28162835368887 -0.211629397505248 RGILTLK ddPTM_PC-9_AZD4547_30min_R2 1 RGILTLK 7 1 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;Q6S8J3;C9JTX5;A5A3E0;P0CG38;P0CG39;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;POTEE;POTEF;POTEI;POTEJ;ACTG1;ACTA1;ACTC1;ACTG2;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;POTE ankyrin domain family member J;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle 0 94.11399999999999 0.0085753 9686500.0 41205.0 41104.0 52699.0 70923.0 67910.0 52538.0 44710.0 65451.0 45690.0 56880.0 False True 54307.332882757146 54390.0641674703 52000.1768270851 54572.798099426975 58481.86871192687 49252.79055463653 48689.1033852533 55337.05186435588 48105.08012201627 54888.64851292458 0.9894091830293371 0.9909164397564484 0.9473757914596981 0.9942456150396337 1.065463812579685 0.8973219762013092 0.8870523269267329 1.008169327603789 0.8764121803926181 1.0 15.744220196768543 -6.7851661670591765 24.999439928611007 0.9313805750687699 0.9941539619449754 0.2947953007958861 0.04904891410458426 310.52864937129726 327182.3016310095 0.017029803173882984 0.015027289221981559 1.639962180993365e-07 6.7851661670591765 0.06277338687620548 RGILTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RGILTLK 7 1 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;Q6S8J3;C9JTX5;A5A3E0;P0CG38;P0CG39;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;POTEE;POTEF;POTEI;POTEJ;ACTG1;ACTA1;ACTC1;ACTG2;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;POTE ankyrin domain family member J;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle 0 ; 94.302 0.0085371 27731000.0 81223.0 79809.0 88679.0 110514.0 109018.0 99028.0 105998.0 104373.0 93704.0 82203.0 False True 94972.44967262559 87731.9100806939 90793.44367698026 104322.25887122205 87656.70549226101 93834.79735116923 95957.10208093644 101633.31934233491 95074.24372944856 97105.75318140996 0.978031131638524 0.903467685553047 0.9349955147082043 1.0743159437353875 0.90269322486489 0.9663155299961472 0.9881711323702145 1.0466251072937633 0.9790794120285932 1.0 16.567269152438087 -7.395385474166173 3.539014552870009 1.0105930318201592 0.9588653912506625 0.17092329425187736 0.047993909173327354 0.43347339170071614 9.875576225805867 0.022194003930396614 0.01411998063311743 4.0235974647891315e-08 7.395385474166173 -0.05172764056949675 RGILTLK ddPTM_PC-9_Lapatinib_30min_R1 2 RGILTLK 7 1 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;Q6S8J3;C9JTX5;A5A3E0;P0CG38;P0CG39;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;POTEE;POTEF;POTEI;POTEJ;ACTG1;ACTA1;ACTC1;ACTG2;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;POTE ankyrin domain family member J;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle 0 ; 98.458 0.0076921 45666000.0 146685.0 143206.0 160579.0 151909.0 147461.0 146384.0 148680.0 131532.0 139246.0 133391.0 False True 144593.24500126526 142874.41530555044 147376.81447286517 163080.8946135689 138787.63389948063 140123.49755777075 156377.922903173 137643.4569011735 123562.64915461477 156447.45661766495 0.9242287994149392 0.9132421734072349 0.9420211594301138 1.0424004208142235 0.8871197838559792 0.8956585206764491 0.9995555458938403 0.8798062932883228 0.7898028630569821 1.0 17.255318679165164 -7.89915523143201 11.12946072735907 0.8749209081128453 0.9420124699809881 0.1119698267952588 0.06525735663205984 0.6585792786752812 67.04725992602926 0.03473332036011707 0.016675750014290756 1.2613765956511472e-08 7.89915523143201 0.0670915618681428 RGLAPNT(ph)PGK ddPTM_PC-9_AZD4547_30min_R2 4 RGLAPNTPGK 10 1 O43663-2;O43663-4;H0YL53;G3V3N7;O43663-3;O43663 O43663-2 PRC1 Protein regulator of cytokinesis 1 1 RGLAPNT(1)PGK;RGLAPNT(1)PGK;RGLAPNT(1)PGK;RGLAPNT(1)PGK 101.38 0.0030768 41696000.0 327509.0 320549.0 377865.0 481540.0 469640.0 404175.0 398558.0 435139.0 433943.0 436320.0 True False 431650.04938960995 424160.19557265536 372854.26320739486 370528.3927188367 404438.5925764882 378901.87335681316 434028.8898908476 367898.2660494715 456880.34106780734 421044.569605472 1.0251884967761857 1.0073997533565218 0.8855458308291864 0.8800217826488772 0.9605600493920539 0.8999091799517864 1.0308383511454433 0.8737751122029677 1.0851115868705166 1.0 18.68361343206439 -8.272035725659364 24.979110329714842 1.042555792209546 0.9451330195984186 0.29310722786456334 0.06034788592765928 1011.4723138517566 2384348.9308396615 0.05564340128423602 0.014983658016351497 5.345203872086768e-09 8.272035725659364 -0.09742277261112753 RGLAPNT(ph)PGK ddPTM_PC-9_Lapatinib_30min_R1 4 RGLAPNTPGK 10 1 O43663-2;O43663-4;H0YL53;G3V3N7;O43663-3;O43663 O43663-2 PRC1 Protein regulator of cytokinesis 1 1 RGLAPNT(1)PGK;RGLAPNT(1)PGK;RGLAPNT(1)PGK;RGLAPNT(1)PGK 97.779 0.009296899999999999 22210400.0 354804.0 278315.0 338502.0 329572.0 325375.0 302077.0 276425.0 288649.0 315879.0 234513.0 True False 349744.4298969151 277670.578717122 310671.6722155064 353809.82429996313 306237.0822118627 289157.8708858805 290736.9339420872 302060.6863049813 280301.380666666 275048.25958106987 1.2715747790210201 1.0095340328277163 1.1295169534564409 1.2863554375470552 1.1133940010320262 1.0512986750990578 1.057039715084593 1.0982097714962984 1.0190989068376484 1.0 18.0693252485282 -6.584340115579774 4.770514804796145 1.0531566273437794 1.1637625290411278 0.38464933675563706 0.0760694594113957 0.2559127785933623 11.745047624730388 0.025790553484046075 0.026017502344085834 2.604113352699988e-07 6.584340115579774 0.11060590169734841 RGLDDDRGPR ddPTM_PC-9_AZD4547_30min_R2 2 RGLDDDRGPR 10 2 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 ; 117.53 0.0019886 3140600.0 7060.7 5035.1 10252.400000000001 15541.900000000001 11052.2 7914.0 7405.799999999999 10945.0 8720.1 8798.7 False True 9305.855728316543 6662.597608252961 10116.446477200838 11958.955074961355 9517.792804858751 7419.13632893132 8064.901853064383 9253.7017410792 9181.026683563015 8490.660191115849 1.0960108541446127 0.784697238881887 1.1914793725682393 1.4084835343516087 1.120972055249324 0.873799700133364 0.9498556851330648 1.0898683415409505 1.0813089296836456 1.0 13.051661019526252 -6.608948175730231 24.999285216551467 1.00105326768228 1.1217376162485861 0.13561873915152922 0.15313069046970898 56.81713607385245 16493.330135214153 0.056136324191766514 0.05613632020296481 2.460661216817696e-07 6.608948175730231 0.12068434856630605 RGLDDDRGPR ddPTM_PC-9_Lapatinib_30min_R1 1 RGLDDDRGPR 10 2 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 106.18 0.0049294 1762000.0 3981.6 2935.6 2666.5 3481.8 3931.5 2981.4 2388.1 3433.9 3773.9 2429.4 False True 3924.821653863983 2928.8027985627277 2447.270662987662 3737.8631869443107 3700.256899626393 2853.892471982851 2511.744132936958 3593.4515300682715 3348.843641071207 2849.3185530279793 1.3774597612797852 1.0278958789814079 0.8588968265366258 1.3118446103444883 1.2986462660323181 1.0016052676700578 0.8815245070677409 1.2611617350574928 1.175313879001834 1.0 11.476401208248245 RGLDDS(ph)T(ph)GGT(ph)PLT(ph)PAAR ddPTM_PC-9_AZD4547_30min_R2 1 RGLDDSTGGTPLTPAAR 17 1 Q9NXR1;Q9NXR1-1;I3L533;I3L2R9;I3L2T8;I3L2R3;I3L522 Q9NXR1 NDE1 Nuclear distribution protein nudE homolog 1 4 RGLDDS(1)T(1)GGT(1)PLT(1)PAAR 47.09 0.032625 2335600.0 4337.0 4047.8 6128.2 8511.3 7051.4 5482.3 4964.5 5804.6 5229.6 5859.7 True False 5716.075784795961 5356.172190956753 6046.93606390525 6549.151283274159 6072.434826023869 5139.490914341691 5406.330882489153 4907.632446438409 5506.025979559997 5654.553686553867 1.0108800979975465 0.9472316451240628 1.0693922808239387 1.1582083478750202 1.073901701643349 0.9089118609949783 0.9561021403590224 0.8679080115745325 0.9737330804114464 1.0 12.46519744157285 -6.760222147206149 24.99998839806034 0.9339984559810175 1.052981926402272 0.455955483731179 0.060129972095237155 31.314267749145912 643147.8902732134 0.02218391099042877 0.021021206440644938 1.7369121486078765e-07 6.760222147206149 0.11898347042125446 RGLDEDR ddPTM_PC-9_AZD4547_30min_R2 2 RGLDEDR 7 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 ; 113.41 0.0057117 11324300.0 25940.2 19199.0 27339.2 40316.0 33671.0 30707.0 23246.0 27679.0 32561.0 31673.0 False True 34188.64401032148 25404.70129309221 26976.664344884048 31021.76907599086 28996.36285376657 28786.886435746 25314.848966530935 23401.84655014447 34282.10798540104 30564.137910510908 1.1185868912914476 0.8311931246834093 0.8826247422344885 1.0149728144408932 0.9487054056183544 0.9418517387937281 0.8282533288081141 0.7656635570308905 1.121644853382615 1.0 14.899552254691768 -7.025612876211236 24.40022343382831 0.9058895617756308 0.9503798575585441 0.0 0.1150490028322213 2500.8039814805406 2382395.6155009023 0.043045931583801746 0.03349464027859477 9.427295575278581e-08 7.025612876211236 0.0444902957829133 RGLDEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RGLDEDR 7 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 ;; 118.74 0.0042977 6304600.0 17108.1 15617.0 16875.9 15562.0 20239.9 20651.6 17632.1 19789.9 21229.2 18785.7 False True 20004.163429622677 17167.35255084259 17278.28545820715 14690.111592684723 16274.036888337861 19568.593740935965 15961.859842650629 19270.436094132292 21539.636888299403 22191.398702480627 0.9014377010578674 0.7736038985646978 0.7786028131825564 0.661973217174572 0.7333488576598237 0.8818098400777471 0.7192813781884942 0.8683741098292367 0.9706299804298335 1.0 14.437712981628671 -8.115059131723246 2.589413020543471 0.993116167538777 0.776010821474345 0.5939455077519633 0.06791153893372424 0.2051607165912456 2.4753812437746685 0.05913908164563252 0.018744505858789198 7.672570157380764e-09 8.115059131723246 -0.217105346064432 RGLDEDR ddPTM_PC-9_Lapatinib_30min_R1 1 RGLDEDR 7 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 113.41 0.0057117 4159200.0 3053.7 4015.0 5197.8 3887.1 3508.1 5481.0 4688.3 4197.1 5321.5 3766.6 False True 3010.153678020004 4005.7035141808665 4770.456948088228 4172.970300985475 3301.7604551899676 5246.590406835044 4931.037233971922 4392.112588266854 4722.136632120728 4417.65179132098 0.6813922464268961 0.9067494912230437 1.0798625997323685 0.94461277124281 0.7474016991734572 1.1876423617503342 1.1162122926165325 0.9942188284046513 1.0689245905252074 1.0 12.109063991555276 -6.767121910006748 24.999877306840908 1.0757140712956808 0.8895156268197276 0.43502497462576717 0.11387042023944449 155.7503956281697 685207.8409096176 0.0416494020011642 0.03772895747331286 1.7095353671961912e-07 6.767121910006748 -0.18619844447595313 RGLDVNK ddPTM_PC-9_AZD4547_30min_R2 2 RGLDVNK 7 1 Q9ULV4;Q9ULV4-2;Q9ULV4-3;H0YHL7;B4E3S0 Q9ULV4 CORO1C Coronin-1C;Coronin 0 ; 110.12 0.006018899999999999 9910900.0 110160.0 99007.0 125488.0 165154.0 135990.0 125946.0 123696.0 136513.0 123391.0 124019.0 False True 145188.58852965722 131009.07656259072 123823.94712759738 127080.29690386415 117110.135858267 118070.57671008124 134704.7043690959 115418.05260666482 129913.1963522809 119677.13255844597 1.2131690108697448 1.0946876296406136 1.0346500160933105 1.0618594729599051 0.9785506500255983 0.9865759162672104 1.1255676125370986 0.9644119151191964 1.085530657152368 1.0 16.86878798848766 -4.579136404363015 1.3725562040468902 1.0273347620072344 1.3701917284286032 0.5812804000960354 0.04786713396987951 1.3946954088874368 1.6685200799905473 0.01328049903049203 0.7576515288692758 2.635503489890483e-05 4.579136404363015 0.34285696642136876 RGLDVNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGLDVNK 7 1 Q9ULV4;Q9ULV4-2;Q9ULV4-3;H0YHL7;B4E3S0 Q9ULV4 CORO1C Coronin-1C;Coronin 0 103.83 0.0066056 3698300.0 30875.0 28517.0 37500.0 36410.0 38528.0 37768.0 36834.0 34189.0 39327.0 28034.0 False True 36101.52769095341 31347.97929771261 38394.14221954197 34370.06574281268 30978.714975562158 35787.37959323586 33344.81686493346 33291.574976239855 39902.08297562557 33116.34228297809 1.0901423648320518 0.946601500547528 1.1593714635349899 1.0378581501882533 0.9354509840141771 1.0806561693146497 1.0068991490667376 1.0052914265640935 1.2049061045046443 1.0 15.015255714777394 RGLDVNK ddPTM_PC-9_Lapatinib_30min_R1 2 RGLDVNK 7 1 Q9ULV4;Q9ULV4-2;Q9ULV4-3;H0YHL7;B4E3S0 Q9ULV4 CORO1C Coronin-1C;Coronin 0 ; 122.18 0.0033537 9643600.0 134741.0 123109.0 119025.0 118059.0 132028.0 130733.0 117804.0 117804.0 134917.0 116575.0 False True 132819.56863152693 122823.94867429457 109239.22394978692 126741.45269327864 124262.37261703517 125141.85434350772 123903.31470060101 123277.60390464573 119721.22672100582 136724.83342357632 0.9714370484551932 0.8983294811834474 0.7989713442280202 0.9269819499478272 0.9088500567564621 0.9152825511647595 0.9062239214199371 0.901647497515899 0.87563629607876 1.0 17.06091577885261 -11.337577139401361 2.6381915914946656 1.0327482252933753 0.8990108010406362 0.343997049496821 0.04123497733975147 23095941.472565584 15970591.516731463 4819010.980889672 0.0111319777442413 4.596453390582828e-12 11.337577139401361 -0.13373742425273905 RGLLYDS(ph)DEEDEERPAR ddPTM_PC-9_AZD4547_30min_R2 2 RGLLYDSDEEDEERPAR 17 2 P49736 P49736 MCM2 DNA replication licensing factor MCM2 1 RGLLYDS(1)DEEDEERPAR;RGLLYDS(1)DEEDEERPAR 90.22 0.0068119 18557400.0 13457.2 12443.1 19693.1 25106.0 20750.2 19867.7 12832.0 27514.0 16539.800000000003 18697.6 True False 17736.309672851326 16465.088736917332 19431.956626757044 19318.199583833375 17869.39290452399 18625.36957825483 13974.023141122116 23262.343508821687 17414.060061329066 18043.002715106515 0.9830021062958434 0.9125470409164173 1.0769801974528124 1.070675424088874 0.9903779978685493 1.032276604528842 0.7744843450820055 1.2892722944249893 0.9651420185593129 1.0 14.139151831319442 -7.7666316362168955 24.999881812814426 1.0954052434264703 0.9847649465964058 0.15228384219978364 0.11457084861498414 238.9805811503003 1150625.7598247835 0.05790571025579169 0.029138114870973442 1.711466346482162e-08 7.7666316362168955 -0.11064029683006449 RGLLYDS(ph)DEEDEERPAR ddPTM_PC-9_Lapatinib_30min_R1 1 RGLLYDSDEEDEERPAR 17 2 P49736 P49736 MCM2 DNA replication licensing factor MCM2 1 RGLLYDS(1)DEEDEERPAR 72.09 0.035108 14212000.0 15007.0 12210.0 16335.0 8411.9 10332.0 11199.0 11331.0 11979.0 13052.0 8873.1 True False 14792.997428053257 12181.728495180161 14991.999354923462 9030.53918727579 9724.29207349355 10720.044876144077 11917.663736991193 12535.588071489516 11581.946316346855 10406.80351233744 1.4214736936770174 1.1705542898680195 1.4405959848430112 0.867753405411175 0.9344168035809689 1.030099671184844 1.1451800471549793 1.2045570051004006 1.1129206295301208 1.0 13.345239387182476 -5.752667642428158 24.998442307050706 1.0499598352246473 1.3268426264977051 0.5891663103942404 0.11519206182126443 155.16158638315383 442188.0591756178 0.033804438876844464 0.05742595045165078 1.7673898541955941e-06 5.752667642428158 0.2768827912730578 RGLNSSFETS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 RGLNSSFETSPK 12 1 M0QZ79;M0QXD7;M0R025;M0QYG0;M0QYA8;Q8IV63-2;Q8IV63 M0QZ79 VRK3 Inactive serine/threonine-protein kinase VRK3 1 RGLNSSFET(0.46)S(0.54)PK 63.727 0.021238 3510800.0 28013.0 21764.0 15791.0 25713.0 25279.0 21687.0 24491.0 20418.0 24062.0 24789.0 True False 36920.5512934031 28798.78738178338 15581.601022343892 19785.265111889894 21769.447197302292 20330.908461654464 26670.651554646352 17262.867258963477 25333.86819645341 23921.14465518437 1.5434274498817264 1.2039050721405127 0.6513735545245712 0.8271036105122956 0.9100503972992051 0.8499136958000125 1.1149404403131724 0.7216572412316457 1.0590575226074253 1.0 14.5459988054085 -4.976113456393416 3.8026013898675406 0.8867912381770131 1.5161610781209005 0.692760877564659 0.13709154527174194 0.11503783159842475 3.5681038500003437 0.033985336648156964 0.1539363814412477 1.0565414590965538e-05 4.976113456393416 0.6293698399438874 RGLNSSFETS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 RGLNSSFETSPK 12 1 M0QZ79;M0QXD7;M0R025;M0QYG0;M0QYA8;Q8IV63-2;Q8IV63 M0QZ79 VRK3 Inactive serine/threonine-protein kinase VRK3 1 RGLNSSFET(0.129)S(0.871)PK;RGLNSSFET(0.082)S(0.917)PK 65.172 0.019372 10466100.0 83036.0 77943.0 54960.0 68494.0 65072.0 57072.0 56909.0 55901.0 54670.0 55842.0 True False 81851.8914130624 77762.5277723038 50441.400951735195 73531.27724928597 61244.59289647431 54631.16360133 59855.46956212443 58498.364536633715 48512.488899378026 65494.215295212125 1.2497575708651338 1.187319023852608 0.7701657424914999 1.122714073568897 0.9351145382903995 0.8341372341829363 0.9139046752805372 0.8931836845888612 0.7407141024701226 1.0 15.999079867368147 -1.5228853708242855 0.5482439864232128 0.877460328584155 18.951502340303236 0.5164877234205805 0.1143976276700321 102.4321161500696 0.9434044761919237 0.05532760446389492 2178.5979811985753 0.029999542327129283 1.5228853708242855 18.07404201171908 RGMDDDRGPR ddPTM_PC-9_AZD4547_30min_R2 1 RGMDDDRGPR 10 2 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 83.78299999999999 0.027375999999999998 828230.0 3353.9 2246.3 4867.8 6734.4 5504.7 4515.1 2856.6 4751.3 3527.3 3863.5 False True 4420.370434546269 2972.3725462093344 4803.249791435983 5181.888125442821 4740.467423038489 4232.77008323955 3110.8318660325335 4017.0957590123003 3713.74587687433 3728.2400409578777 1.185645340961084 0.7972588979130373 1.2883424185857701 1.389901956020907 1.2715027388152145 1.1353265982712974 0.8343968821367208 1.0774777682984726 0.9961123307715392 1.0 11.86427903487717 -7.022508896935205 21.922952147113328 0.9836542733435495 1.1840143479090477 0.2901816474420975 0.15556789942153199 240.11239138520818 233860.4876039709 0.0640237352915715 0.05013530556644569 9.494915477662271e-08 7.022508896935205 0.2003600745654982 RGMDDDRGPRR ddPTM_PC-9_AZD4547_30min_R2 1 RGMDDDRGPRR 11 3 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 50.108000000000004 0.035886 821570.0 0.0 0.0 658.6 3545.2 1205.5 0.0 561.55 0.0 0.0 477.2 False True 0.0 0.0 649.866533678405 2727.908912793997 1038.1371334446742 0.0 611.5268621335043 0.0 0.0 460.49337324837563 0.0 0.0 1.411239708172494 5.923883102922849 2.2544018953444 0.0 1.327981894331552 0.0 0.0 1.0 8.847036585069631 -6.756729810567671 24.960922770361403 0.4569954245552487 2.0057611011981664 0.17033905374617853 1.5966565477501151 232.34532830067073 1231440.3295769833 0.5974756220249361 0.5788782612019424 1.7509356667330695e-07 6.756729810567671 1.5487656766429176 RGNDAVMAR ddPTM_PC-9_Lapatinib_30min_R1 1 RGNDAVMAR 9 1 P21399 P21399 ACO1 Cytoplasmic aconitate hydratase 0 76.1 0.0232 408770.0 1014.9 1148.3 2114.5 814.27 727.07 818.28 742.02 759.82 1122.8 0.0 False True 1000.4273398901337 1145.6411819013415 1940.6539722060409 874.154132125091 684.3051720746186 783.2840719038459 780.4381648682561 795.1240110592832 996.3384403918358 0.0 0.0 RGNDPLT(ph)SSPGR ddPTM_PC-9_Lapatinib_30min_R1 2 RGNDPLTSSPGR 12 1 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 RGNDPLT(0.369)S(0.369)S(0.262)PGR;RGNDPLT(0.669)S(0.165)S(0.165)PGR 105.66 0.0060158 251330000.0 79668.0 70913.0 72197.0 60877.0 70099.0 66388.0 60308.0 66006.0 72168.0 52967.0 True False 78531.91971067806 70748.80530538163 66261.24134847923 65354.09765971876 65975.91463993653 63548.739997986595 63430.45315068971 69072.87972674989 64039.6798772693 62122.27537590883 1.264150729114036 1.1388637147830258 1.0666261167596496 1.0520235658506358 1.0620331312835678 1.0229622082167156 1.0210581110699013 1.1118858623381416 1.0308650075960362 1.0 15.922823052375456 -4.621126917649789 1.2474871773074478 1.0453018159532506 1.4301326338392204 0.8535904592234824 0.028410997070410463 0.7118495269945077 0.7445316926945699 0.008409589961228203 0.38823215998490446 2.392616439136464e-05 4.621126917649789 0.38483081788596984 RGNDPLTS(ph)SPGR ddPTM_PC-9_AZD4547_30min_R2 2 RGNDPLTSSPGR 12 1 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 RGNDPLT(0.269)S(0.557)S(0.173)PGR;RGNDPLT(0.07)S(0.465)S(0.465)PGR 98.0 0.005575500000000001 186957000.0 56737.0 50694.0 82308.0 102581.0 85668.0 82664.0 66050.0 88211.0 60574.0 74303.0 True False 74778.18579708747 67079.84412479911 81216.54214090822 78932.5353106512 73774.47693731937 77495.00701222863 71928.32204419543 74580.01683712557 63775.817975728096 71701.67458607299 1.0429071040359223 0.9355408295837543 1.132700771770864 1.1008464692954705 1.0289087021079002 1.0807977283599024 1.003160978588448 1.0401433058247103 0.8894606484980984 1.0 16.129719192881247 -8.178442448771863 7.904495466239967 0.9451916603746163 1.0461700294048968 0.3359479908969262 0.05675348100151664 0.31458048523968174 26.644656850438107 0.03899393181500665 0.01460000462160394 6.630672092611175e-09 8.178442448771863 0.10097836903028046 RGNDPLTS(ph)SPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGNDPLTSSPGR 12 1 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 RGNDPLT(0.082)S(0.459)S(0.459)PGR 71.531 0.012459999999999999 11709000.0 16598.0 18364.0 18131.0 25122.0 29342.0 19612.0 22792.0 17533.0 19204.0 15497.0 True False 19407.7135745569 20187.056556552052 18563.311802200413 23714.495786622916 23592.645733309415 18583.512195047166 20632.97676020968 17072.777327749074 19484.822169601386 18306.48342581549 1.0601551987416913 1.1027271643053307 1.0140293671051397 1.2954151398176854 1.2887590251243703 1.015132822770375 1.1270857586505887 0.9326082421527957 1.0643672908869117 1.0 14.160067063563652 -7.370055733534091 1.8524690710832799 1.0052186929916866 1.1430783629087196 0.24624371568251602 0.09862073334025824 0.53284562400042 3.56342121554667 0.05864000565935193 0.03353279466809998 4.265247788505083e-08 7.370055733534091 0.1378596699170329 RGNDPLTS(ph)SPGR ddPTM_PC-9_Lapatinib_30min_R1 2 RGNDPLTSSPGR 12 1 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 RGNDPLT(0.039)S(0.923)S(0.039)PGR;RGNDPLT(0.037)S(0.762)S(0.201)PGR 120.55 0.0007162999999999999 61545000.0 85294.0 67513.0 83876.0 70885.0 79811.0 71760.0 66884.0 66998.0 81017.0 58281.0 True False 84077.69191899596 67356.6777964865 76980.03905072308 76098.11936542804 75116.67389446328 68690.99208073024 70346.92625407463 70110.97166822392 71892.01231316826 68354.79319544883 1.230018964121363 0.985398018890813 1.1261834825629833 1.1132813926865157 1.0989232851554391 1.0049184390671786 1.029144014128309 1.0256921042501526 1.051747930940342 1.0 16.060754886025208 -6.730445958174832 9.524070603628719 1.0243464547145062 1.1049049538023865 0.37534049873056785 0.05677953990804703 0.3860468277080846 112.52881949673208 0.01782945058252553 0.017671643078397917 1.860176021500726e-07 6.730445958174832 0.08055849908788026 RGNDPLTSS(ph)PGR ddPTM_PC-9_AZD4547_30min_R2 2 RGNDPLTSSPGR 12 1 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 RGNDPLT(0.089)S(0.044)S(0.867)PGR;RGNDPLTS(0.039)S(0.96)PGR 130.66 6.3944e-05 299778000.0 26564.0 22326.2 38013.0 49286.0 36262.0 35110.0 32377.0 39046.0 30770.0 36742.0 True False 35010.79943447544 29542.70753736315 37508.922782747024 37923.87416110934 31227.647227682104 32914.56614970665 35258.490277440076 33012.337887818954 32396.43938179997 35455.67376339441 0.9874526618253615 0.833229336847746 1.0579103088846802 1.069613693260659 0.8807517644728147 0.9283300148053798 0.994438591485521 0.9310875914562924 0.9137166479472493 1.0 15.11372889150896 -6.2923816543882936 24.98094862412766 0.9399415180128247 0.9811256341684836 0.09425437355276611 0.06827936717491397 2010.4793729976761 1623134.8320743837 0.022229351134697352 0.025207590749016764 5.100565694833426e-07 6.2923816543882936 0.04118411615565898 RGNDPLTSS(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RGNDPLTSSPGR 12 1 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 RGNDPLT(0.014)S(0.241)S(0.745)PGR;RGNDPLTS(0.228)S(0.772)PGR;RGNDPLT(0.068)S(0.068)S(0.863)PGR 142.39 0.00011944 208520000.0 65596.0 53492.0 68971.0 69537.0 81176.0 69105.0 78023.0 53996.0 62768.0 62200.0 True False 76700.10721994437 58802.332243687786 70615.5302139742 65641.06733199565 65270.145526791785 65481.01214760027 70632.09660239733 52578.662213491094 63685.863254610515 73476.3676250709 1.0438745095746065 0.8002890472721711 0.9610645231444382 0.8933629880418619 0.8883148097337481 0.8911846660919786 0.9612899886778961 0.7155860300795641 0.8667530161477421 1.0 16.164992686744124 RGNGLIK ddPTM_PC-9_Lapatinib_30min_R1 1 RGNGLIK 7 1 M0R210;P62249;M0R3H0;M0R1M5;Q6IPX4 M0R210 RPS16 40S ribosomal protein S16 0 85.359 0.022892 0.0 28442.0 24918.0 21219.0 20520.0 23413.0 25562.0 21172.0 29246.0 29031.0 18564.0 False True 28036.41186437598 24860.303901957348 19474.45572770868 22029.109252713333 22035.893371729046 24468.77284793237 22268.182564608393 30604.8759277721 25761.223070017277 21772.762665024864 1.287682794127585 1.1418075089704727 0.8944411890821683 1.0117737281038872 1.0120853155271319 1.1238249010649577 1.022754112888915 1.4056496365954922 1.1831857751060393 1.0 14.410236856908185 -7.707280414157765 24.999884932920946 1.2208189795224522 1.0641168370123262 0.14722579932934554 0.13411576488339352 135.36556306029655 62484.61753788456 0.06341998192983236 0.036615503577033096 1.9620929885341228e-08 7.707280414157765 -0.15670214251012604 RGPCIIYNEDNGIIK ddPTM_PC-9_Lapatinib_30min_R1 1 RGPCIIYNEDNGIIK 15 1 P36578;H3BM89 P36578 RPL4 60S ribosomal protein L4 0 119.62 5.9739e-05 9891900.0 109190.0 95388.0 120240.0 101560.0 106180.0 100880.0 102070.0 99551.0 97936.0 90519.0 False True 107632.93057700622 95167.13494662118 110354.33133982254 109029.06119422828 99934.70115791188 96565.59756276583 107354.68516765445 104176.50288879327 86905.41636819995 106165.08854101424 1.0138260331730888 0.8964070604985718 1.0394597023972707 1.0269765955322274 0.9413141601563738 0.9095795886371829 1.011205158333953 0.9812689304973101 0.8185875183877062 1.0 16.695949900944726 -6.29558506505846 23.479486318003534 0.944395969503409 0.9904196477634237 0.13427362366835982 0.06252351557069866 702.2333642507593 482871.78128782456 0.019508389813025148 0.02212206806848955 5.063081694649965e-07 6.29558506505846 0.046023678260014744 RGPEVTSQGVQTS(ph)SPACK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGPEVTSQGVQTSSPACK 18 1 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;F8WB05;F8WB06 Q99700;F8WB06 ATXN2 Ataxin-2 1 RGPEVTSQGVQT(0.001)S(0.842)S(0.157)PACK 88.319 0.0022819000000000003 2476100.0 17265.0 20117.0 19597.0 14657.0 19965.0 15388.0 16932.0 12490.0 11334.0 11565.0 True False 20187.623500706424 22114.082811378656 20064.26680203638 13835.815808635141 16053.001569951692 14581.026190974197 15328.078382935693 12162.150734248891 11499.738308178608 13661.642951510372 1.4776863641041482 1.618698636018285 1.4686569450871327 1.0127490418058038 1.1750418033123127 1.0672966818652059 1.1219791380392568 0.89024071097571 0.8417536857751978 1.0 13.73784337236235 -5.71816453463506 4.382867193618546 1.022304217530454 1.546274521380099 0.8471956656417139 0.09870939366195783 0.07970613875070122 3.2831463313744615 0.03006087647951862 0.05202359190328985 1.9135308369567902e-06 5.71816453463506 0.523970303849645 RGPEVTSQGVQTS(ph)SPACK ddPTM_PC-9_Lapatinib_30min_R1 1 RGPEVTSQGVQTSSPACK 18 1 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;F8WB05;F8WB06 Q99700;F8WB06 ATXN2 Ataxin-2 1 RGPEVTSQGVQT(0.023)S(0.488)S(0.488)PACK 70.117 0.0047345 24410000.0 39488.0 78404.0 62992.0 57559.0 72140.0 64444.0 72650.0 69237.0 61920.0 54815.0 True False 38924.893878787676 78222.46035512726 57813.04091615175 61792.08087119522 67896.86703269702 61687.880346301325 76411.46152081985 72454.00378209517 54945.917553493455 64289.699713603666 0.6054608133525189 1.2167183966263795 0.8992582198034212 0.9611505598325271 1.056108013183488 0.9595297632607888 1.1885490500222577 1.126992412546048 0.8546612878620574 1.0 15.972299991714424 -4.745128838924541 24.992764937127617 1.0306403361407401 0.6054595962612193 0.5569522500046729 0.11337850675350539 725.6178787892322 1111809.7518579531 0.02760419085305286 0.7318420061016693 1.7983373365796556e-05 4.745128838924541 -0.4251807398795209 RGPEVTSQGVQTSS(ph)PACK ddPTM_PC-9_AZD4547_30min_R2 2 RGPEVTSQGVQTSSPACK 18 1 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;F8WB05;F8WB06 Q99700;F8WB06 ATXN2 Ataxin-2 1 RGPEVTSQGVQT(0.001)S(0.163)S(0.836)PACK;RGPEVTSQGVQT(0.155)S(0.361)S(0.484)PACK 86.439 0.00079917 45408000.0 145207.0 164010.0 171450.0 152230.0 168525.0 178268.0 183840.0 200208.0 169581.0 157199.0 True False 191379.80550677117 217023.02510964405 169176.46097656028 117135.7254300546 145128.21270324662 167120.8737788635 200201.40385473004 169270.453922155 178544.70545352687 151695.5108576519 1.261604937580244 1.430648961743464 1.1152370958117024 0.772176610684099 0.9567073665049461 1.1016863507298278 1.319758262606697 1.115856711679458 1.1769939956962188 1.0 17.21081886681654 -5.357709653735104 5.859095846261325 1.0670897666217458 1.344071440477844 0.38386716594738857 0.14082435344541322 0.2415615940783958 11.846479069454576 0.04129110529476683 0.08782861499426671 4.388239741728168e-06 5.357709653735104 0.2769816738560982 RGPEVTSQGVQTSS(ph)PACK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RGPEVTSQGVQTSSPACK 18 1 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;F8WB05;F8WB06 Q99700;F8WB06 ATXN2 Ataxin-2 1 RGPEVTSQGVQTS(0.059)S(0.941)PACK;RGPEVTSQGVQTS(0.037)S(0.963)PACK 126.29 2.0084e-05 36027000.0 90202.0 104281.0 93830.0 79063.0 92046.0 73090.0 86545.0 54942.0 56203.0 55114.0 True False 105471.41702929189 114633.32851088037 96067.26305225641 74633.35643570454 74010.24705773966 69257.03173240862 78346.83106846035 53499.83071586092 57024.86254937028 65105.731917816076 1.6200020170640277 1.7607255941087292 1.4755576847446172 1.1463407942316866 1.1367700642881011 1.0637624321593189 1.2033783932781634 0.8217376433674771 0.8758808306057231 1.0 15.99049694360668 -5.708858755167998 0.9139662802988832 0.976692493339016 1.788071871013488 0.8597581688506399 0.1110437892819108 0.2776346395357351 0.4151728034326483 0.048769500108842866 0.17006131452398254 1.954975165535791e-06 5.708858755167998 0.811379377674472 RGPEVTSQGVQTSS(ph)PACK ddPTM_PC-9_Lapatinib_30min_R1 2 RGPEVTSQGVQTSSPACK 18 1 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;F8WB05;F8WB06 Q99700;F8WB06 ATXN2 Ataxin-2 1 RGPEVTSQGVQT(0.004)S(0.079)S(0.917)PACK;RGPEVTSQGVQT(0.001)S(0.123)S(0.876)PACK 163.04 3.2146e-07 30096400.0 49729.4 74145.0 71305.0 65286.9 77852.0 66009.0 82247.0 80363.0 74361.5 62949.7 True False 49020.24963674492 73973.32180795529 65442.578145259766 70088.31641671389 73272.89842292097 63185.94894449448 86505.3472223383 84096.95835955505 65986.12480869038 73830.47176979716 0.6639568793436629 1.0019348384851654 0.8863898140771633 0.9493142158870217 0.9924479238245327 0.8558248028200033 1.1716753956558925 1.139054869130035 0.8937519052354779 1.0 16.171928756782272 -4.357553821475324 1.8692872843360924 0.9941756035718357 1.3333804645918268e-65 0.48074025859467984 0.0991928612895266 3.4884727055768123 4.340118001146052 0.027919410785344722 9.024037103505295 4.389814599441973e-05 4.357553821475324 -0.9941756035718357 RGPGLYYVDSEGNR ddPTM_PC-9_AZD4547_30min_R2 1 RGPGLYYVDSEGNR 14 1 P28074;P28074-3 P28074 PSMB5 Proteasome subunit beta type-5 0 127.3 1.8492000000000002e-05 3834300.0 8651.1 6417.6 10229.0 14019.0 15252.0 11587.0 12752.0 13017.0 9328.1 11144.0 False True 11401.96984594151 8491.963696991952 10093.356776490136 10787.136141390898 13134.523068683668 10862.463058292542 13886.90329610266 11005.521750902511 9821.164322306415 10753.851951969613 1.060268441193594 0.7896671569331595 0.9385805961966489 1.0030950946293424 1.2213784537249488 1.0100997397777116 1.29134224258678 1.023402758384339 0.9132694374230833 1.0 13.392565894863019 -5.920145330068492 3.7202711211723094 1.087079944289171 0.9160901140602623 0.22321275235714377 0.12065539063322973 0.2993949066208326 8.165389454842241 0.03487983049152635 0.053432268136338154 1.2018621823471146e-06 5.920145330068492 -0.17098983022890868 RGPGLYYVDSEGNR ddPTM_PC-9_Lapatinib_30min_R1 2 RGPGLYYVDSEGNR 14 1 P28074;P28074-3 P28074 PSMB5 Proteasome subunit beta type-5 0 ; 181.71 1.7622000000000002e-05 12170200.0 31094.0 30589.0 29538.0 25244.0 34787.0 29763.0 29534.0 24476.0 33381.0 27075.0 False True 30650.59385805876 30518.173049882545 27109.499659977326 27100.52797151536 32740.897053873425 28490.105870941698 31063.12600902814 25613.244314030977 29621.280262486544 31754.877674830223 0.9652247497824012 0.9610546563078741 0.8537113553885629 0.8534288259279289 1.0310509581910545 0.8971883363141949 0.9782158925981194 0.8065924415238018 0.9328104036743046 1.0 14.954690592121045 -5.046971340765056 24.930181746585262 0.9146745599984415 0.9641824765260861 0.06195723188962243 0.06681800467452699 909.0324287144675 482471.26669857156 0.016703832058920624 0.044197002016950884 8.974880180745687e-06 5.046971340765056 0.049507916527644635 RGPGT(ph)PGPVAR ddPTM_PC-9_AZD4547_30min_R2 3 RGPGTPGPVAR 11 1 Q8N6S5 Q8N6S5 ARL6IP6 ADP-ribosylation factor-like protein 6-interacting protein 6 1 RGPGT(1)PGPVAR;RGPGT(1)PGPVAR;RGPGT(1)PGPVAR 83.85600000000001 0.0105 19240000.0 14312.2 16466.0 21692.1 20509.2 20974.5 14475.2 15100.6 21297.1 18132.1 15376.7 True False 18863.18188774654 21788.312489820106 21404.448580633638 15781.120803981337 18062.55272122382 13570.063455717285 16444.52414626158 18006.1225536718 19090.525788584182 14838.366413303214 1.2712438392702659 1.4683767662110012 1.4425070782349503 1.0635349178217424 1.2172871472583389 0.9145254320954871 1.1082435686126728 1.2134841566877983 1.2865651957124289 1.0 13.857044650945344 -5.759616656366271 24.99894872464853 1.119352551825896 1.4014760305373875 0.5589309703524388 0.11356493666485315 35.95926371230768 493170.5477541764 0.032103601411507934 0.05215441719013907 1.7393354302899313e-06 5.759616656366271 0.28212347871149146 RGPGT(ph)PGPVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RGPGTPGPVAR 11 1 Q8N6S5 Q8N6S5 ARL6IP6 ADP-ribosylation factor-like protein 6-interacting protein 6 1 RGPGT(1)PGPVAR;RGPGT(1)PGPVAR;RGPGT(1)PGPVAR 84.17299999999999 0.010317 16318000.0 15012.2 22494.199999999997 21190.1 17295.5 34218.5 19852.5 20198.6 14868.900000000001 15002.1 13910.3 True False 17553.46895553461 24727.275517011163 21695.352347901764 16326.489207767556 27513.630564557567 18811.399951671123 18285.242382799723 14478.607129901806 15221.477331315193 16432.12727612578 1.0682408102472543 1.504812803692033 1.3203008949074366 0.9935712481662855 1.6743803222929081 1.1447939536716094 1.1127739017312952 0.8811158096942056 0.9263242108299917 1.0 14.00423164085108 -7.365399092879082 2.2185026344757235 0.9340385991154638 1.3070495323311186 0.40805368031116507 0.1893474418636044 0.3035089907413541 2.9166600228546953 0.09547705752737289 0.0572058501223972 4.311227165387795e-08 7.365399092879082 0.3730109332156548 RGPGT(ph)PGPVAR ddPTM_PC-9_Lapatinib_30min_R1 4 RGPGTPGPVAR 11 1 Q8N6S5 Q8N6S5 ARL6IP6 ADP-ribosylation factor-like protein 6-interacting protein 6 1 RGPGT(1)PGPVAR;RGPGT(1)PGPVAR;RGPGT(1)PGPVAR;RGPGT(1)PGPVAR 78.529 0.015527000000000001 16201200.0 20974.6 37388.4 16586.699999999997 13246.900000000001 14657.0 18191.300000000003 20119.4 15751.5 24381.5 7475.0 True False 20675.498357729426 37301.829456936444 15223.005552513567 14221.121216362972 13794.904076770716 17413.30050499149 21161.084087019743 16483.37219367786 21635.398721422833 8767.043790188587 2.3583204159271887 4.254778503408621 1.7363898158635873 1.6221113475306437 1.573495514213004 1.9862225992847373 2.4137080404117097 1.8801516894582875 2.467810043978055 1.0 13.097874738710823 -5.283777023291204 24.91393998855286 1.8755483522062066 3.306549535746433 0.5043309169188703 0.5824391211385601 507.7094264992052 566264.985991804 0.1441917930710107 0.3005173504250666 5.20263042905827e-06 5.283777023291204 1.4310011835402263 RGPLSQNGSFGPSPVSGGECS(ph)PPLTVEPPVRPLSATLNR ddPTM_PC-9_AZD4547_30min_R2 1 RGPLSQNGSFGPSPVSGGECSPPLTVEPPVRPLSATLNR 39 2 Q5JRA6-4;Q5JRA6-2;Q5JRA6 Q5JRA6-4 MIA3 Melanoma inhibitory activity protein 3 1 RGPLSQNGSFGPS(0.001)PVS(0.032)GGECS(0.695)PPLT(0.226)VEPPVRPLS(0.02)AT(0.026)LNR 49.503 0.00094937 11209000.0 4465.2 1434.9 4586.8 5307.7 4661.5 3041.4 4875.8 4799.3 3621.4 1582.3 True False 5885.040718070307 1898.7033640011457 4525.976035038119 4084.0917681475485 4014.331188347034 2851.220777206433 5309.736754323818 4057.6784619425716 3812.81981076537 1526.904158614637 3.854230591270257 1.2434987181669888 2.964152012752749 2.6747531893901266 2.629065593736574 1.8673213777827096 3.477452546295605 2.6574545881282496 2.4970917717748238 1.0 10.576393793927974 RGPLSQNGSFGPSPVSGGECS(ph)PPLTVEPPVRPLSATLNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGPLSQNGSFGPSPVSGGECSPPLTVEPPVRPLSATLNR 39 2 Q5JRA6-4;Q5JRA6-2;Q5JRA6 Q5JRA6-4 MIA3 Melanoma inhibitory activity protein 3 1 RGPLSQNGSFGPSPVS(0.018)GGECS(0.92)PPLT(0.038)VEPPVRPLS(0.012)AT(0.012)LNR 54.596000000000004 6.0422e-05 6928300.0 8418.1 5488.3 6603.9 11719.0 9457.4 8832.2 9801.5 9244.0 4398.7 7650.3 True False 9843.118064946235 6033.142153088905 6761.362021430217 11062.422423510629 7604.290360513952 8369.023883800513 8873.030963285153 9001.354794827612 4463.02266597717 9037.238830258524 1.089173170016207 0.6675868886953292 0.7481667961227044 1.2240931805931006 0.8414395705747238 0.9260598332069425 0.9818298630745965 0.9960293142512993 0.4938480380792922 1.0 13.141666334472978 -10.495385362506191 4.471631086258675 1.0000026217293676 0.8908789828530884 0.02799121737020349 0.2003054136952093 56682880.92948761 44346876.12126068 1328.640051897075 0.04719895495895988 3.19605789317455e-11 10.495385362506191 -0.10912363887627918 RGPNYTSGYGTNSELSNPS(ph)ETESER ddPTM_PC-9_AZD4547_30min_R2 2 RGPNYTSGYGTNSELSNPSETESER 25 1 B4DXZ6;P51114;P51114-3;P51114-2;E7EU85;E9PFF5 B4DXZ6 FXR1 Fragile X mental retardation syndrome-related protein 1 1 RGPNYTSGYGTNSELS(0.008)NPS(0.973)ET(0.016)ES(0.002)ER;RGPNYTSGYGTNSELS(0.002)NPS(0.888)ET(0.095)ES(0.016)ER 130.7 1.0629000000000001e-07 49878000.0 58285.0 68895.0 76788.0 79545.0 75120.0 73235.0 73674.0 97065.0 88744.0 83776.0 True False 76818.41759668724 91163.96143484501 75769.74094761204 61207.12920799912 64690.88466558602 68655.60387279323 80230.84327455027 82065.83458180455 93434.82666553317 80843.02773942993 0.9502169790607713 1.127666342837642 0.9372452154047234 0.7571107975480523 0.8002036350505715 0.849245826047996 0.9924274921165392 1.015125693291893 1.155756152116032 1.0 16.302835734207008 -7.651570978749252 2.462831642248812 1.0720563718581155 0.9050291881384017 0.3144199676720383 0.10197463115242562 0.4021064097094346 4.89283629236319 0.06949202204433116 0.033579742130576046 2.2306376143007695e-08 7.651570978749252 -0.1670271837197138 RGPNYTSGYGTNSELSNPS(ph)ETESER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RGPNYTSGYGTNSELSNPSETESER 25 1 B4DXZ6;P51114;P51114-3;P51114-2;E7EU85;E9PFF5 B4DXZ6 FXR1 Fragile X mental retardation syndrome-related protein 1 1 RGPNYTSGYGTNSELS(0.002)NPS(0.924)ET(0.072)ES(0.002)ER;RGPNYTSGYGTNSELS(0.001)NPS(0.923)ET(0.069)ES(0.008)ER;RGPNYTSGYGTNSELSNPS(0.888)ET(0.11)ES(0.001)ER;RGPNYTSGYGTNSELS(0.01)NPS(0.826)ET(0.068)ES(0.097)ER 125.85 3.3849e-08 40585000.0 53459.4 70235.5 64491.100000000006 61456.700000000004 62390.600000000006 49794.4 59813.8 48125.9 49320.6 41602.3 True False 62509.0205487208 77208.01626975118 66028.81240785876 58013.48034430973 50165.609804669584 47183.094005968655 54147.80384958891 46862.64611860603 50041.82046959188 49144.467666374396 1.2719441987463158 1.5710418677009785 1.343565523104383 1.1804681808366333 1.0207783741850127 0.9600896346314938 1.10180873699112 0.9535691064300686 1.018259487706924 1.0 15.58474139693895 -5.9040035109943405 2.0719602795804697 1.0080956939032915 1.4281776273683198 0.8307766110067857 0.07842506714719792 0.1123979035479627 0.9807554874387308 0.023396396807645464 0.03998320687857359 1.2473734299822893e-06 5.9040035109943405 0.4200819334650283 RGPNYTSGYGTNSELSNPS(ph)ETESER ddPTM_PC-9_Lapatinib_30min_R1 3 RGPNYTSGYGTNSELSNPSETESER 25 1 B4DXZ6;P51114;P51114-3;P51114-2;E7EU85;E9PFF5 B4DXZ6 FXR1 Fragile X mental retardation syndrome-related protein 1 1 RGPNYTSGYGTNSELS(0.006)NPS(0.813)ET(0.129)ES(0.052)ER;RGPNYTSGYGTNSELSNPS(0.953)ET(0.043)ES(0.004)ER;RGPNYTSGYGTNSELSNPS(0.927)ET(0.068)ES(0.005)ER 154.32 7.6983e-08 83590000.0 57773.0 87980.0 80267.0 71562.0 97434.0 78543.0 81988.0 87181.0 88094.0 66999.0 True False 56949.14642572935 87776.28771547496 73667.75709958024 76824.90820383397 91703.12368261439 75183.89898267559 86232.93746963496 91231.74752988784 78171.92604905456 78579.68787944416 0.7247311355206694 1.1170353317022599 0.9374910881880858 0.9776687879149845 1.1670079909620412 0.9567854112378463 1.0973947567968494 1.1610092886835373 0.9948108494524032 1.0 16.261868816935355 -4.753856370010484 24.99959033572281 1.0476552482399826 0.7247305604574088 0.5883919576740031 0.08045929969555948 192.22147811564062 633661.6756580942 0.01976849572879926 0.2039213199618239 1.7625588639797853e-05 4.753856370010484 -0.32292468778257377 RGPTS(ph)SNPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGPTSSNPR 9 1 E7EUC9;P40692-2;H0Y4N0;H0Y806;A0A087WX20;A0A669KBB4;A0A669KBK2;H0Y818;A0A669KAW3;P40692-3;P40692 E7EUC9 MLH1 DNA mismatch repair protein Mlh1 1 RGPT(0.007)S(0.496)S(0.496)NPR 71.153 0.016387 1205400.0 934.68 1238.9 1859.9 1280.1 2495.5 2167.0 791.5 1110.0 1179.3 1104.6 True False 1092.902863228512 1361.8898043951392 1904.2470697100293 1208.3801471401953 2006.5246890966416 2053.358705214523 716.5233900362387 1080.8636761422163 1196.5450314835928 1304.855235991211 0.8375663698803392 1.0437094988246745 1.4593550435221272 0.9260645271674677 1.537737393200112 1.5736295096786919 0.5491209831349175 0.8283399156697691 0.9169944668801959 1.0 10.349674044022498 -7.26823190380396 24.99998238498821 0.8093088463446286 1.231866069167914 0.37344563756192095 0.25739460886156296 612.45392654639 2254135.309729834 0.10991966335502498 0.07597016868397084 5.392226124837618e-08 7.26823190380396 0.42255722282328534 RGPTS(ph)SNPR ddPTM_PC-9_Lapatinib_30min_R1 1 RGPTSSNPR 9 1 E7EUC9;P40692-2;H0Y4N0;H0Y806;A0A087WX20;A0A669KBB4;A0A669KBK2;H0Y818;A0A669KAW3;P40692-3;P40692 E7EUC9 MLH1 DNA mismatch repair protein Mlh1 1 RGPT(0.029)S(0.486)S(0.486)NPR 54.772 0.042956 845720.0 2496.3 1250.0 1147.1 2121.7 2068.3 985.92 796.11 1151.8 2494.3 1006.2 True False 2460.7023042346477 1247.1057017997705 1052.7898659340506 2277.7368957837157 1946.6466604342552 943.7544998917721 837.3286804038535 1205.3168328526274 2213.3656678565694 1180.120329322777 2.085128306913198 1.0567614766160613 0.8921038302409414 1.930088686033242 1.6495323502742778 0.7997103993906742 0.7095282231807347 1.0213507918673934 1.8755423602665415 1.0 10.204718254136134 -6.753583095400875 24.99987495100162 1.0593296342369714 1.4844332295839797 0.19421639680460046 0.44512779128205676 336.097793522497 1069512.1255842247 0.15473833321104621 0.15203420626450312 1.7636682820763678e-07 6.753583095400875 0.42510359534700837 RGQS(ph)PLPR ddPTM_PC-9_AZD4547_30min_R2 3 RGQSPLPR 8 1 H3BTS1;H3BN52;Q9BQ65-3;Q9BQ65-2;Q9BQ65 H3BTS1 USB1 U6 snRNA phosphodiesterase 1 RGQS(1)PLPR;RGQS(1)PLPR;RGQS(1)PLPR 84.68700000000001 0.0063213 52258100.0 18832.7 17416.9 26990.5 33744.7 26936.4 22564.5 21121.800000000003 24051.4 22285.3 22681.100000000002 True False 24821.106855505408 23046.572318957114 26632.58833472059 25965.380765417904 23196.74581610875 21153.538247936656 23001.59928165159 20334.808776189333 23463.25546165834 21887.041592589558 1.1340549041543035 1.0529779559956676 1.2168199261675348 1.1863357894019435 1.0598392531936627 0.9664868665986704 1.050923176818899 0.9290798251634989 1.0720158483914268 1.0 14.417789342376262 -6.480544962906203 4.591907174805002 1.002656513555368 1.1447753107872702 0.6090654130291226 0.05426651123391223 0.1450782738705858 6.919142156759936 0.01755860795281142 0.01931068042140304 3.307158709692061e-07 6.480544962906203 0.14211879723190224 RGQS(ph)PLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RGQSPLPR 8 1 H3BTS1;H3BN52;Q9BQ65-3;Q9BQ65-2;Q9BQ65 H3BTS1 USB1 U6 snRNA phosphodiesterase 1 RGQS(1)PLPR;RGQS(1)PLPR;RGQS(1)PLPR;RGQS(1)PLPR 80.834 0.0085898 27869000.0 24993.699999999997 23452.199999999997 24443.5 28871.7 30452.4 28503.4 30336.9 28653.7 27473.7 23851.9 True False 29224.639761923285 25780.37942580972 25026.32574248997 27254.112252314328 24485.470824382508 27008.63152663204 27463.169211864042 27901.57073610469 27875.450887366056 28176.060658463484 1.0372152486527542 0.9149745856351941 0.8882123745347844 0.9672790168460891 0.8690168267730357 0.9585666305172164 0.9746986828556069 0.9902580447392548 0.9893310220068989 1.0 14.782182299721692 -7.203497762362707 3.0015437748311937 0.9893619785921681 0.9323524999786851 0.24322235937067782 0.043545968883204625 0.37507849675386634 6.695625061187438 0.018655314598391887 0.01332286528350249 6.258960887490179e-08 7.203497762362707 -0.057009478613483044 RGQS(ph)PLPR ddPTM_PC-9_Lapatinib_30min_R1 3 RGQSPLPR 8 1 H3BTS1;H3BN52;Q9BQ65-3;Q9BQ65-2;Q9BQ65 H3BTS1 USB1 U6 snRNA phosphodiesterase 1 RGQS(1)PLPR;RGQS(1)PLPR;RGQS(1)PLPR 90.05 0.0044769 38563900.0 30206.4 23255.1 26422.4 20318.3 26370.9 24776.800000000003 21192.8 19350.0 26878.699999999997 18442.699999999997 True False 29775.651196824674 23201.25424473908 24250.05226541352 21812.575561861853 24819.8155091842 23717.154021541774 22290.05948683319 20249.071640647973 23851.33776074103 21630.496121646964 1.3765588652877154 1.0726177575520408 1.121104764728212 1.0084177190939543 1.1474455033116642 1.0964683328648466 1.0304922902127132 0.9361353307279663 1.1026717846231706 1.0 14.400779135188285 RGQS(ph)SPPPAPPICLR ddPTM_PC-9_AZD4547_30min_R2 4 RGQSSPPPAPPICLR 15 1 O43379;O43379-4;H7C3R4;O43379-3;O43379-2 O43379 WDR62 WD repeat-containing protein 62 1 RGQS(0.576)S(0.424)PPPAPPICLR;RGQS(0.746)S(0.254)PPPAPPICLR;RGQS(0.61)S(0.39)PPPAPPICLR;RGQS(0.756)S(0.244)PPPAPPICLR 95.755 0.0040793 35906400.0 88310.0 87555.0 106665.0 155519.0 135643.0 115146.0 97818.0 134573.0 91065.0 122188.0 True False 116390.7430378907 115855.44151865669 105250.55240632713 119666.49729459824 116811.31081861127 107945.90241737761 106523.61250142482 113777.83502989967 95878.50998711778 117910.23531113249 0.9871131435771265 0.9825732364365675 0.8926328755820055 1.0148949069504565 0.9906799906757758 0.9154922143318452 0.9034297338169031 0.9649529977586037 0.8131483219766369 1.0 16.847329432717906 -6.773508812123534 24.252498275409977 0.916215760943712 0.9718768578422119 0.20041226673705392 0.05386306522422008 253.12749580803782 508634.0192274113 0.018206578028365655 0.01618488318049262 1.6845782452156285e-07 6.773508812123534 0.05566109689849985 RGQS(ph)SPPPAPPICLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RGQSSPPPAPPICLR 15 1 O43379;O43379-4;H7C3R4;O43379-3;O43379-2 O43379 WDR62 WD repeat-containing protein 62 1 RGQS(0.84)S(0.16)PPPAPPICLR;RGQS(0.63)S(0.37)PPPAPPICLR;RGQS(0.835)S(0.165)PPPAPPICLR 94.61 0.001375 23919100.0 69513.0 53324.0 62585.0 70820.0 100806.0 77464.0 71705.0 81599.0 68076.0 63392.0 True False 81280.17795566775 58617.65431396109 64077.2637549342 66852.18500153802 81053.78794192596 73401.6514724217 64912.58330075622 79457.11271128719 69071.48271286115 74884.46778920399 1.085407700091658 0.7827745331510779 0.8556816339445514 0.8927376661035177 1.0823845095632953 0.9801986131362201 0.8668364110362896 1.0610626616851302 0.9223739548673017 1.0 16.192378891728282 -6.080861258055833 24.999863151554575 0.9828087857943955 0.8918962369002724 0.15331871921331652 0.09171097836433013 169.40671441108273 52373.733238527 0.026431395717431937 0.03412279629461746 8.301159182507007e-07 6.080861258055833 -0.09091254889412304 RGQS(ph)SPPPAPPICLR ddPTM_PC-9_Lapatinib_30min_R1 4 RGQSSPPPAPPICLR 15 1 O43379;O43379-4;H7C3R4;O43379-3;O43379-2 O43379 WDR62 WD repeat-containing protein 62 1 RGQS(0.595)S(0.405)PPPAPPICLR;RGQS(0.98)S(0.02)PPPAPPICLR;RGQS(0.5)S(0.5)PPPAPPICLR;RGQS(0.5)S(0.5)PPPAPPICLR 130.47 1.7984e-05 35045100.0 105061.0 94752.0 103362.0 89286.0 104348.0 97573.0 78840.0 77509.0 106387.0 69683.0 True False 103562.81087417234 94532.60756554562 94863.97534885828 95852.39028936469 98210.45579606124 93400.03024377218 82921.94943291726 81110.35110051601 94404.5757552246 81727.61370323895 1.26717037463273 1.1566789152660553 1.1607334540969072 1.1728274685397544 1.2016802075327089 1.1428209635841924 1.0146136131420043 0.9924473189078507 1.1551123479270662 1.0 16.31853599062311 -7.104608253046286 3.9045895744070207 1.0405403144874497 1.1862761924948855 0.6574045715425679 0.051442975701870564 0.15106168204450168 4.082224493083912 0.020062068566646572 0.01544042124682967 7.85944260809207e-08 7.104608253046286 0.14573587800743582 RGQSQS(ph)LR ddPTM_PC-9_AZD4547_30min_R2 1 RGQSQSLR 8 1 Q3KP66-3;Q3KP66 Q3KP66-3 C1orf106 Uncharacterized protein C1orf106 1 RGQS(0.031)QS(0.969)LR 76.92699999999999 0.011123000000000001 1373500.0 3916.5 3505.9 4687.1 4199.0 3180.1 4500.4 3784.4 4260.0 6541.6 5855.2 True False 5161.865531739312 4639.1136133888185 4624.945991503267 3230.9854239033025 2738.598007521699 4218.98927656337 4121.204268645771 3601.7148850614362 6887.375621058915 5650.2112301841735 0.91357036426602 0.8210513597449351 0.8185439097915836 0.5718344487092717 0.484689491410825 0.7466958498869871 0.7293894158557744 0.6374478295290272 1.2189589628553437 1.0 12.464089087595724 -8.258329927295101 24.999326310284243 1.1094795020111032 0.7113957435455917 0.598988983859974 0.12894280123516086 182.18981444904082 1464798.2167948259 0.1031388730687726 0.03523755054939426 5.516581932283656e-09 8.258329927295101 -0.3980837584655116 RGS(ph)ASGSEPAGDSDR ddPTM_PC-9_AZD4547_30min_R2 3 RGSASGSEPAGDSDR 15 1 A0A0C4DG27;P50747 A0A0C4DG27 HLCS Biotin--protein ligase;Biotin--[methylmalonyl-CoA-carboxytransferase] ligase;Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase;Biotin--[methylcrotonoyl-CoA-carboxylase] ligase;Biotin--[acetyl-CoA-carboxylase] ligase 1 RGS(0.99)AS(0.009)GS(0.001)EPAGDSDR;RGS(0.995)AS(0.004)GS(0.001)EPAGDSDR;RGS(0.995)AS(0.004)GS(0.001)EPAGDSDR 109.35 0.0014885 24434000.0 6264.299999999999 5985.219999999999 6949.46 8688.6 8540.25 7171.03 6911.45 9104.02 7898.21 7024.9 True False 8256.217094465603 7919.825317643697 6857.305619703502 6685.57750753185 7354.583702945565 6722.624360482228 7526.555660747231 7697.20289856737 8315.693256084704 6778.960389213147 1.2179178842235314 1.1682949689816633 1.0115571158396235 0.9862246013666209 1.084913213927074 0.9916895769415378 1.1102816993478346 1.1354547683764833 1.226691524753094 1.0 12.726848325527035 -10.645652473514245 13.423364563131415 0.9999999975287704 1.0966909413545067 0.11799620456934634 0.0830813968533595 0.0 0.0 0.08659081791176 0.021001357988163702 2.2612445153403555e-11 10.645652473514245 0.09669094382573629 RGS(ph)ASGSEPAGDSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RGSASGSEPAGDSDR 15 1 A0A0C4DG27;P50747 A0A0C4DG27 HLCS Biotin--protein ligase;Biotin--[methylmalonyl-CoA-carboxytransferase] ligase;Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase;Biotin--[methylcrotonoyl-CoA-carboxylase] ligase;Biotin--[acetyl-CoA-carboxylase] ligase 1 RGS(0.961)AS(0.001)GSEPAGDS(0.038)DR;RGS(0.987)AS(0.01)GS(0.003)EPAGDSDR;RGS(0.985)AS(0.013)GS(0.002)EPAGDSDR;RGS(0.996)AS(0.003)GS(0.001)EPAGDSDR;RGS(0.976)AS(0.004)GSEPAGDS(0.019)DR 144.08 6.6603e-05 41982440.0 28602.52 28271.09 28124.660000000003 32165.99 37292.1 30284.37 31406.87 27334.6 27442.05 28785.4 True False 33444.36171047929 31077.65697807521 28795.258557767003 30363.8338638466 29984.980708579787 28696.204324613536 28431.783907552046 26617.0957134027 27843.33806599196 34003.96515489896 0.9835429944163718 0.9139421487025564 0.8468206112609331 0.8929497993992644 0.881808358877813 0.84390759118512 0.8361314269684773 0.7827644685598665 0.8188262145063564 1.0 15.053415366376127 -1.522878745283306 0.682702129961389 0.8486588979473151 16.1395497459792 0.29306769914069164 0.055752292942574194 289.75022027514615 1.6480817846488196 0.021723520308419522 6741.782043047407 0.029999999999794955 1.522878745283306 15.290890848031884 RGS(ph)ASGSEPAGDSDR ddPTM_PC-9_Lapatinib_30min_R1 2 RGSASGSEPAGDSDR 15 1 A0A0C4DG27;P50747 A0A0C4DG27 HLCS Biotin--protein ligase;Biotin--[methylmalonyl-CoA-carboxytransferase] ligase;Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase;Biotin--[methylcrotonoyl-CoA-carboxylase] ligase;Biotin--[acetyl-CoA-carboxylase] ligase 1 RGS(0.84)AS(0.143)GS(0.017)EPAGDSDR;RGS(0.999)AS(0.001)GSEPAGDSDR 191.44 1.3597999999999998e-07 34330000.0 31028.8 27187.7 29722.5 26468.5 30152.0 33885.2 32236.1 28808.8 35809.9 25777.8 True False 30586.32362201497 27124.748551057324 27278.830782167912 28415.0817863276 28378.518641112816 32436.00898625921 33905.12752555131 30147.362019695032 31776.61196703564 30233.45838324059 1.0116713488183007 0.8971765058175902 0.9022729201661386 0.9398554881197124 0.9386461277894682 1.072851427550861 1.1214439015136306 0.9971522820031306 1.0510412525167967 1.0 14.883858396787426 -6.753946172944057 24.529204504977486 1.0528789266533904 0.9337873051705043 0.609526042988749 0.04411908619789902 88.03831250830886 288195.2022827414 0.014819338141360473 0.014535736812285989 1.7621944416822068e-07 6.753946172944057 -0.1190916214828861 RGS(ph)DASDFDLLETQSACSDTSESSAAGGQGNSR ddPTM_PC-9_AZD4547_30min_R2 4 RGSDASDFDLLETQSACSDTSESSAAGGQGNSR 33 1 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y6T5;H0Y4F5;H0Y314 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 RGS(0.705)DAS(0.289)DFDLLET(0.004)QS(0.002)ACSDTSESSAAGGQGNSR;RGS(0.638)DAS(0.333)DFDLLET(0.026)QS(0.002)ACSDTSESSAAGGQGNSR;RGS(0.871)DAS(0.125)DFDLLET(0.004)QSACSDTSESSAAGGQGNSR;RGS(0.724)DAS(0.262)DFDLLET(0.013)QS(0.001)ACSDTSESSAAGGQGNSR 83.898 1.4828999999999999e-10 31913700.0 12445.3 17385.9 26026.3 37273.0 30799.8 29715.3 19070.000000000004 28444.4 23847.2 30249.699999999997 True False 16402.646521678857 23005.552175195146 25681.17425671766 28680.28571210949 26523.77941324699 27857.197593516907 20767.19305651488 24048.971567286728 25107.714306976308 29190.667210292082 0.561914066695111 0.7881132695412943 0.8797734588150475 0.9825155932714467 0.9086390256915814 0.9543186318021186 0.7114326269730743 0.8238582350323089 0.8601281404805916 1.0 14.833219566408085 -4.782874787233407 2.3033453975069516 0.8832338455613703 0.48276300408294026 0.6116241039315147 0.07931826723092711 0.4380583264095575 2.789910425462256 0.02216801737201146 0.3605754075640667 1.6486376467590413e-05 4.782874787233407 -0.40047084147843004 RGS(ph)DASDFDLLETQSACSDTSESSAAGGQGNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RGSDASDFDLLETQSACSDTSESSAAGGQGNSR 33 1 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y6T5;H0Y4F5;H0Y314 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 RGS(0.776)DAS(0.187)DFDLLET(0.033)QS(0.004)ACSDTSESSAAGGQGNSR;RGS(0.891)DAS(0.109)DFDLLETQSACSDTSESSAAGGQGNSR;RGS(0.896)DAS(0.104)DFDLLETQSACSDTSESSAAGGQGNSR;RGS(0.729)DAS(0.258)DFDLLET(0.011)QS(0.001)ACSDTSESSAAGGQGNSR 86.631 8.2535e-12 33611300.0 14020.5 20914.9 20478.9 20447.7 28520.8 23470.0 23354.2 23176.2 20699.9 11471.3 True False 16393.893732502416 22991.19305024126 20967.194642660732 19302.081661337837 22932.353978275896 22239.19188342633 21141.92110623415 22567.849307213706 21002.596877136617 13550.955883239165 1.2097961113414597 1.6966473249815894 1.5472852855048054 1.4244073870251541 1.6923052643570589 1.6411529987292945 1.5601793178578685 1.6654064481995186 1.549897812235829 1.0 13.726107002299718 -8.602931423344565 19.403462055387138 0.9999999994272266 1.565275677770597 0.5845954844600676 0.13990632193557828 6829.9164474673435 1655458.8780449843 0.12913546410401033 0.03334263346198985 2.494988663493474e-09 8.602931423344565 0.5652756783433703 RGS(ph)DASDFDLLETQSACSDTSESSAAGGQGNSR ddPTM_PC-9_Lapatinib_30min_R1 4 RGSDASDFDLLETQSACSDTSESSAAGGQGNSR 33 1 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y6T5;H0Y4F5;H0Y314 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 RGS(0.521)DAS(0.479)DFDLLETQSACSDTSESSAAGGQGNSR;RGS(0.93)DAS(0.07)DFDLLETQSACSDTSESSAAGGQGNSR;RGS(0.786)DAS(0.209)DFDLLET(0.005)QSACSDTSESSAAGGQGNSR;RGS(0.93)DAS(0.07)DFDLLETQSACSDTSESSAAGGQGNSR 102.28 1.3372e-16 38117500.0 37653.0 42492.299999999996 46587.200000000004 38583.8 42687.299999999996 43936.899999999994 34172.799999999996 35858.5 49800.1 32399.1 True False 37116.06131528547 42393.91169006913 42756.98024779253 41421.38136378364 40176.51694046085 42057.82120891637 35942.10037520544 37524.616817890186 44191.08831969852 37999.241265912926 0.9767579582853485 1.1156515308661814 1.1252061573699768 1.0900581165271985 1.057297872326231 1.106806867921444 0.9458636324785559 0.9875096335555389 1.162946597024293 1.0 15.21368299197849 -7.212333371360249 24.98749758201571 1.0230387525130211 1.0819795113715878 0.14208664185546638 0.06533612248262875 716.2811340128695 364478.8046018928 0.024898106251955005 0.0192858902484223 6.132910524542767e-08 7.212333371360249 0.058940758858566644 RGS(ph)DELTVPR ddPTM_PC-9_AZD4547_30min_R2 1 RGSDELTVPR 10 1 A0A087WVV7;A0A590UJ70;A0A087X165;Q9C0H9-2;Q9C0H9 A0A087WVV7 SRCIN1 SRC kinase signaling inhibitor 1 1 RGS(1)DELTVPR 104.81 0.0011697 4263900.0 6604.7 6821.4 7477.3 11342.0 10506.0 5201.9 6875.4 9838.5 5576.1 7466.4 True False 8704.85721370576 9026.284150252575 7378.146116418976 8727.277132153198 9047.423246760465 4876.624370668158 7487.297280585333 8318.18589123871 5870.841262166232 7205.003608595291 1.2081683350333374 1.2527799624533937 1.024030870382512 1.2112800501226528 1.2557139091460328 0.6768385743555401 1.0391802263156784 1.1545012803762424 0.8148283583317772 1.0 12.814783437629941 -6.7125989688395515 24.999999924302045 0.9531053385896643 1.1857785259050515 0.465920551445132 0.13502105444522963 113.54333871754928 58119.09902253038 0.044737949501759945 0.044737862142829925 1.9382108980308364e-07 6.7125989688395515 0.23267318731538722 RGS(ph)DELTVPR ddPTM_PC-9_Lapatinib_30min_R1 4 RGSDELTVPR 10 1 A0A087WVV7;A0A590UJ70;A0A087X165;Q9C0H9-2;Q9C0H9 A0A087WVV7 SRCIN1 SRC kinase signaling inhibitor 1 1 RGS(1)DELTVPR;RGS(1)DELTVPR;RGS(1)DELTVPR;RGS(1)DELTVPR 133.88 5.0619e-05 15931000.0 39170.1 36572.0 45502.1 34532.0 35409.8 39734.5 31032.4 32800.3 44890.1 30747.1 True False 38611.52719108338 36487.319780976984 41761.0929811854 37071.598475375074 33327.065182345345 38035.14806064351 32639.105829300657 34324.321681382215 39834.104224290655 36061.69526706452 1.0707074890721415 1.0118026762402708 1.1580457510916353 1.0280048733380793 0.924168010836231 1.054724348896081 0.9050907226513628 0.9518221877031648 1.1046098617740667 1.0 15.138179599278617 -5.997588359847582 24.994924850143516 0.9856843390954112 1.0766267632668538 0.2805228520492613 0.06434844803101424 96.38115966281148 998890.2411701059 0.017741855441581588 0.026129953045259044 1.0055684531844384e-06 5.997588359847582 0.0909424241714426 RGS(ph)DIDNPTLTVMDISPPSR ddPTM_PC-9_AZD4547_30min_R2 2 RGSDIDNPTLTVMDISPPSR 20 1 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 RGS(1)DIDNPTLTVMDISPPSR;RGS(1)DIDNPTLTVMDISPPSR 99.859 0.00012657 17928400.0 29434.0 33884.0 42748.0 46020.0 40435.0 32673.0 35830.0 46158.0 38676.0 43728.0 True False 38793.39973476697 44836.34036226553 42181.133588952966 35410.800001912336 34821.298208905326 30629.952144954877 39018.80058809273 39025.34170532059 40720.334401381086 42197.09602976734 0.9193381389894869 1.0625456389377217 0.9996217170773289 0.8391762309172246 0.8252060327644618 0.7258782007972164 0.9246797590186651 0.9248347724637431 0.9650032403333042 1.0 15.364856096784973 -5.750537619432441 24.66427565725746 0.8756222299182174 1.000706277330011 0.2636762680612791 0.08063916595645318 224.35342554104434 507574.1418903266 0.022938501426628746 0.039224449718238595 1.7760794141727957e-06 5.750537619432441 0.1250840474117937 RGS(ph)DIDNPTLTVMDISPPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RGSDIDNPTLTVMDISPPSR 20 1 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 RGS(1)DIDNPTLTVMDISPPSR;RGS(1)DIDNPTLTVMDISPPSR 108.49 3.672e-05 13621600.0 62711.0 65366.0 57343.0 66699.0 80081.0 49377.0 73442.0 58279.0 61697.0 45516.0 True False 73326.7337012915 71855.10449115562 58710.274594538554 62962.07127107563 64389.702916268565 46787.58319675935 66485.0420859653 56749.23800170467 62599.20190574343 53767.69049554227 1.3637694501193205 1.3363993102347018 1.0919247982095504 1.1710019658794093 1.1975538157363657 0.870180265612085 1.2365240439605154 1.0554524004784915 1.1642531291339984 1.0 15.714451883854192 -5.241960011279225 5.919564622257978 1.1029682080618508 1.3535304079970476 0.4965988589937482 0.10132018156011469 0.13464664181256528 17.887019633046283 0.0251588964502665 0.06414779875448698 5.728487750018486e-06 5.241960011279225 0.2505621999351968 RGS(ph)DIDNPTLTVMDISPPSR ddPTM_PC-9_Lapatinib_30min_R1 4 RGSDIDNPTLTVMDISPPSR 20 1 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 RGS(1)DIDNPTLTVMDISPPSR;RGS(0.998)DIDNPT(0.001)LTVMDISPPSR;RGS(1)DIDNPTLTVMDISPPSR;RGS(0.999)DIDNPT(0.001)LTVMDISPPSR 101.61 0.00012048 18702200.0 81607.8 94090.0 97017.5 92488.7 101263.6 82227.8 81482.5 90183.0 88128.9 76604.6 True False 80444.05780696229 93872.14038587258 89041.09564838024 99290.62753125864 95307.47413989759 78711.10867636386 85701.2651530656 94373.2314092276 78202.89524354128 89845.6030407869 0.8953588721580885 1.0448161869786523 0.9910456676211363 1.105125060891227 1.060791746220805 0.8760707926979092 0.9538726688067316 1.0503934329027245 0.8704142728947991 1.0 16.45516028087542 -6.738565235562635 24.998604896795086 0.9535324182884356 1.024022189609214 0.19000854119391652 0.0710310695577413 408.38817097163104 446316.7352256613 0.02341247725169681 0.023397807563074895 1.825722485909815e-07 6.738565235562635 0.0704897713207785 RGS(ph)DPASGEVEASQLR ddPTM_PC-9_AZD4547_30min_R2 2 RGSDPASGEVEASQLR 16 1 Q8WWA1-3;Q8WWA1-2;Q8WWA1 Q8WWA1-3 TMEM40 Transmembrane protein 40 1 RGS(1)DPASGEVEASQLR;RGS(1)DPASGEVEASQLR 144.75 1.3493e-05 108208000.0 24737.1 34252.0 50415.0 54844.0 41107.0 35600.0 36847.1 48971.0 43725.0 28082.0 True False 32602.98323635605 45323.28916563332 49746.46415942417 42200.56313135335 35400.00260846967 33373.926372245995 40126.42051770892 41403.657191629936 46036.21423364327 27098.857727495557 1.2031128235813346 1.6725165917103046 1.8357402610719442 1.5572819915776381 1.3063282210803835 1.2315621089217907 1.4807421375918397 1.5278746288121279 1.6988248986942773 1.0 14.725944419851501 -6.115422427381034 6.3878179881087 1.3996879673598943 1.5987190673876561 0.13588824758702478 0.22968853138891668 0.504018361782317 24.786918485246186 0.06916088642932774 0.08993374130796235 7.666154589138858e-07 6.115422427381034 0.1990311000277618 RGS(ph)DPASGEVEASQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RGSDPASGEVEASQLR 16 1 Q8WWA1-3;Q8WWA1-2;Q8WWA1 Q8WWA1-3 TMEM40 Transmembrane protein 40 1 RGS(0.995)DPAS(0.004)GEVEASQLR;RGS(1)DPASGEVEASQLR;RGS(1)DPASGEVEASQLR 119.54 4.9058000000000004e-05 88520000.0 27382.9 39539.5 38996.6 34926.0 51640.7 34905.1 35004.1 43635.7 38167.9 28132.0 True False 32018.284133072328 43464.72025254791 39926.42683942906 32969.20945161976 41522.075540866725 33074.61510908326 31688.258240262167 42490.30911084585 38726.03333092736 33232.10890721051 0.9634743381009199 1.3079133910492569 1.201441261248577 0.9920889927171096 1.2494565318380233 0.9952607943550317 0.9535434037226158 1.2785920156161545 1.1653197646606417 1.0 15.020290228806704 -5.667263962932179 19.100538737858756 1.0988870528510812 1.1726454084034907 0.045005128721561816 0.1324056621951944 9.823678568925871 1976.101310624779 0.03580598544878557 0.06201772761519973 2.1514736777585453e-06 5.667263962932179 0.0737583555524095 RGS(ph)DPASGEVEASQLR ddPTM_PC-9_Lapatinib_30min_R1 3 RGSDPASGEVEASQLR 16 1 Q8WWA1-3;Q8WWA1-2;Q8WWA1 Q8WWA1-3 TMEM40 Transmembrane protein 40 1 RGS(0.942)DPAS(0.057)GEVEASQLR;RGS(1)DPASGEVEASQLR;RGS(1)DPASGEVEASQLR 133.92 1.6686000000000002e-06 105002800.0 41011.2 54893.0 33564.5 17464.4 29236.5 31511.8 23178.4 25879.5 40909.8 18726.100000000002 True False 40426.372767467 54765.8986311159 30804.95637271681 18748.790235530545 27516.86655117055 30164.113771593602 24378.4641392178 27081.95604775965 36302.107524707826 21962.881434040195 1.8406679874349412 2.4935661923774 1.4025917530553305 0.8536580362571123 1.2528805308998414 1.3734133138305953 1.109984781023937 1.233078461452941 1.6528845558690362 1.0 14.422779721592761 -5.386588218050674 5.404741108558741 1.2188873222368173 2.1577213708884386 0.6929985574085915 0.25039869157716327 0.11145866233337635 4.391920872675162 0.06388401809086254 0.13633241240643046 4.105932277782243e-06 5.386588218050674 0.9388340486516213 RGS(ph)DPASGEVEASQLRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGSDPASGEVEASQLRR 17 2 Q8WWA1-3;Q8WWA1-2;Q8WWA1 Q8WWA1-3 TMEM40 Transmembrane protein 40 1 RGS(0.998)DPAS(0.002)GEVEASQLRR 90.765 0.0065517 17356000.0 56689.0 42707.0 61941.0 51915.0 68858.0 42520.0 57966.0 46701.0 42344.0 42656.0 True False 66285.3280412132 46946.66871926965 63417.90835255065 49006.37086070089 55365.769201288895 40290.176347817964 52475.04084250237 45475.148233799664 42963.20089302236 50389.19513528978 1.3154670929599876 0.9316812581193784 1.2585616456520117 0.9725571271603733 1.0987627219017395 0.7995796765485736 1.0413947018128056 0.9024781624652585 0.8526272502998035 1.0 15.62082679192777 -6.218054397897545 1.2298152974870422 0.922775607353559 1.1480932280231382 0.3715211254038585 0.125763523497889 0.5018327082843096 1.5513698069255883 0.047205831156621574 0.07144507189087228 6.052650570540539e-07 6.218054397897545 0.22531762066957917 RGS(ph)FDATGSGFSMTFSSSSYSSSGYGR ddPTM_PC-9_AZD4547_30min_R2 1 RGSFDATGSGFSMTFSSSSYSSSGYGR 27 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 RGS(0.97)FDAT(0.009)GS(0.02)GFS(0.001)MTFSSSSYSSSGYGR 73.968 2.3365e-05 17792000.0 16633.0 17234.0 16452.0 21852.0 22145.0 16014.0 18162.0 26472.0 18670.0 19348.0 True False 21921.948012107736 22804.553470761555 16233.835730454168 16814.359010034514 19070.54900052451 15012.642048459204 19778.382815543955 22381.36066604373 19656.85808443957 18670.63240907286 1.1741406253306623 1.2214130175729798 0.869485048753113 0.900577904466894 1.0214195525191376 0.8040778544364634 1.0593311668400045 1.1987467899141793 1.0528222962007148 1.0 14.188483174707628 -10.647563126359623 15.067289806287588 0.999999076031979 1.0288557089001524 0.004480399714215322 0.13453131123382875 0.0 0.0 0.140772733685134 0.034142402952397226 2.2513181552789978e-11 10.647563126359623 0.028856632868173415 RGS(ph)FDATGSGFSMTFSSSSYSSSGYGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGSFDATGSGFSMTFSSSSYSSSGYGR 27 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 RGS(0.596)FDAT(0.169)GS(0.169)GFS(0.062)MT(0.003)FSSSSYSSSGYGR 49.662 0.007805500000000001 25512000.0 8462.4 10306.0 10770.0 16214.0 19619.0 16751.0 16166.0 18548.0 20679.0 9806.3 True False 9894.91717998135 11329.111570018813 11026.797645452445 15305.582146497243 15774.797786169906 15872.54807154983 14634.639448295438 18061.13465323046 20981.391254175545 11584.104563371915 0.8541805821805467 0.9779876820035472 0.951890375741114 1.3212572506374265 1.3617623787727757 1.370200690499433 1.2633379963237805 1.5591308378153317 1.8112225368300938 1.0 13.499858909560526 -5.809106528767218 2.2724681421269577 1.4159657659050098 0.9104453938151976 0.5294985829270287 0.19697999767139293 0.2329934556397621 2.4551171482987915 0.05989255302052575 0.10811150550330813 1.5520062692382298e-06 5.809106528767218 -0.5055203720898122 RGS(ph)FDATGSGFSMTFSSSSYSSSGYGR ddPTM_PC-9_Lapatinib_30min_R1 1 RGSFDATGSGFSMTFSSSSYSSSGYGR 27 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 RGS(0.92)FDAT(0.025)GS(0.055)GFS(0.001)MTFSSSSYSSSGYGR 60.945 0.007083 0.0 6031.9 9703.8 5807.9 6966.6 5460.2 1719.6 6288.0 6625.4 4494.3 5418.5 True False 5945.883999885014 9681.331447299695 5330.396881142335 7478.947003896325 5139.0417711662285 1646.0567165833859 6613.561872579704 6933.240271211837 3988.104606922898 6355.080505302591 0.9356111216724716 1.5234002841068224 0.8387615037598227 1.1768453598118853 0.8086509316252223 0.2590142981209977 1.0406731853454005 1.0909759939983197 0.6275458829507005 1.0 12.63369468587425 -6.269245337971796 21.7109825994283 0.793562094811454 1.1275726294165376 0.23103694929362972 0.28018464737605636 146.1073803441421 406372.731786025 0.08741616463557249 0.1013401580226368 5.379657935670941e-07 6.269245337971796 0.33401053460508356 RGS(ph)FSSENYWR ddPTM_PC-9_AZD4547_30min_R2 4 RGSFSSENYWR 11 1 Q6P6C2-3;Q6P6C2;K7ER58;Q6P6C2-1 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 RGS(0.842)FS(0.135)S(0.023)ENYWR;RGS(0.995)FS(0.004)SENYWR;RGS(0.997)FS(0.002)SENYWR;RGS(0.989)FS(0.01)S(0.002)ENYWR 111.88 0.00080565 158013200.0 34067.5 24219.1 26272.3 57385.5 45269.7 42934.2 34268.4 35163.700000000004 33595.4 36523.299999999996 True False 44900.256351979806 32047.45044468615 25923.91213598413 44156.15957213694 38984.783566902 40249.51768683383 37318.22121331275 29729.958146440084 35371.18425763156 35244.63038382733 1.2739601994119123 0.9092860414672339 0.7355421763163053 1.2528478548720667 1.1061198015795026 1.14200424996663 1.0588342339500578 0.8435315627563579 1.0035907277910425 1.0 15.105115855253484 -7.672386218934112 12.640828725941983 0.9427213968121336 1.0609471334414176 0.11055665152336658 0.1537944582536997 1.4366511575917957 196.1653358965097 0.0754883845201274 0.043564208550366204 2.126247329035757e-08 7.672386218934112 0.11822573662928393 RGS(ph)FSSENYWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RGSFSSENYWR 11 1 Q6P6C2-3;Q6P6C2;K7ER58;Q6P6C2-1 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 RGS(0.966)FS(0.033)S(0.001)ENYWR;RGS(0.614)FS(0.338)S(0.048)ENYWR;RGS(0.742)FS(0.215)S(0.042)ENYWR 116.98 0.00055344 92356500.0 26050.2 22969.7 35560.6 31802.1 45923.7 25878.0 39518.0 37118.9 36640.1 32165.5 True False 30459.984345097146 25249.98001454113 36408.49956832651 30020.3314407993 36925.28065103883 24520.912124384606 35774.56895445622 36144.56820572548 37175.89214624098 37996.85052804209 0.8016449764071195 0.6645282349363764 0.9581978259344585 0.7900742041407871 0.971798455342702 0.6453406475436143 0.9415140585942564 0.9512516880589984 0.978394041337841 1.0 15.213592221372002 -7.494915305841133 24.657065464867234 0.9681703451099997 0.8110919196359474 0.39382726098388177 0.09917460215200345 640.7580220544663 564997.1308944854 0.04045851019243474 0.02720015084927464 3.1995190046778245e-08 7.494915305841133 -0.15707842547405226 RGS(ph)FSSENYWR ddPTM_PC-9_Lapatinib_30min_R1 4 RGSFSSENYWR 11 1 Q6P6C2-3;Q6P6C2;K7ER58;Q6P6C2-1 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 RGS(0.987)FS(0.01)S(0.002)ENYWR;RGS(0.982)FS(0.015)S(0.003)ENYWR;RGS(0.996)FS(0.004)SENYWR;RGS(0.955)FS(0.044)S(0.001)ENYWR 113.53 0.00071155 119686200.0 25664.0 21358.600000000002 28994.899999999998 27100.3 34958.799999999996 43687.3 37879.6 23450.0 43674.4 27375.5 True False 25298.02665379879 21309.145473968463 26611.051245550687 29093.34646595063 32902.5921156452 41818.89601907036 39840.820341693725 24539.57260843384 38755.329160179186 32107.318699439147 0.7879208753187074 0.6636849895018077 0.8288157443061581 0.9061281864828793 1.0247692254731924 1.3024723867646055 1.2408641380069418 0.7642984092864316 1.2070559215166157 1.0 14.970614569354966 -5.981759268604762 1.798976294076654 1.0984421543077254 0.7355597567084625 0.5196533517001898 0.1449230423008873 0.2917557204798734 1.9048581029616505 0.049460986426363034 0.08234511396057152 1.0428953508153025e-06 5.981759268604762 -0.3628823975992629 RGS(ph)GDTSISIDTEASIR ddPTM_PC-9_AZD4547_30min_R2 4 RGSGDTSISIDTEASIR 17 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 RGS(0.946)GDT(0.023)S(0.008)IS(0.008)IDT(0.014)EAS(0.001)IR;RGS(0.819)GDT(0.133)S(0.043)IS(0.005)IDTEASIR;RGS(0.823)GDT(0.123)S(0.051)IS(0.003)IDTEASIR;RGS(0.757)GDT(0.22)S(0.022)IS(0.001)IDTEASIR 132.87 3.397e-05 19683720.0 52367.5 45907.399999999994 58770.299999999996 74951.3 72275.3 63146.7 55860.1 66472.5 61007.1 58233.200000000004 True False 69019.27568833357 60746.06928186369 57990.96742216815 57672.43577104157 62241.12215748964 59198.126866581646 60831.54068464743 56200.70251109071 64231.810757536885 56194.47339280658 1.2282217720216002 1.080997215815884 1.0319692297284084 1.0263008493362655 1.107602196436938 1.0534510476284586 1.082518208853514 1.000110849304354 1.14302718540573 1.0 15.77814063097693 -4.768385274734344 3.84921961577706 1.057199532260961 1.2474371594747284 0.5860709755634135 0.04324464968008526 0.1705871103600829 4.5416764883755745 0.010116111898340292 0.09386346234138146 1.7045695469257643e-05 4.768385274734344 0.19023762721376736 RGS(ph)GDTSISIDTEASIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RGSGDTSISIDTEASIR 17 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 RGS(0.943)GDT(0.053)S(0.004)ISIDTEASIR;RGS(0.918)GDT(0.063)S(0.017)IS(0.002)IDTEASIR;RGS(0.988)GDT(0.01)S(0.002)ISIDTEASIR 101.05 0.0005038999999999999 15365500.0 17037.899999999998 14071.400000000001 19273.8 19778.0 17203.9 18055.3 16899.6 16186.0 17174.2 14581.3 True False 19922.079956135876 15468.31559735714 19733.360488293532 18669.90278114114 13832.919294229494 17108.448283460908 15298.747545491377 15761.134650484591 17425.34018460571 17224.774264492706 1.156594545172265 0.8980271880394772 1.1456382641235565 1.08389825575987 0.803082762178474 0.9932465889395373 0.8881827599348192 0.9150270655781381 1.0116440376537446 1.0 14.072197455678964 -6.221344948945413 24.995819177282975 0.931500245939157 1.0640100523935085 0.36443793927680024 0.08760570559259077 579.2702622793817 361130.70476306614 0.024720421704365357 0.03191360473097116 6.006964302155704e-07 6.221344948945413 0.1325098064543515 RGS(ph)GDTSISIDTEASIR ddPTM_PC-9_Lapatinib_30min_R1 6 RGSGDTSISIDTEASIR 17 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 RGS(0.993)GDT(0.004)S(0.001)IS(0.001)IDTEASIR;RGS(0.917)GDT(0.079)S(0.004)ISIDTEASIR;RGS(0.891)GDT(0.077)S(0.023)IS(0.002)IDT(0.006)EASIR;RGS(0.786)GDT(0.199)S(0.015)ISIDTEASIR;RGS(0.984)GDT(0.011)S(0.004)IS(0.001)IDTEASIR;RGS(0.8)GDT(0.084)S(0.028)IS(0.028)IDT(0.044)EAS(0.015)IR 137.99 9.5788e-05 27565300.0 59497.00000000001 49510.0 62331.4 54079.09999999999 53353.9 58858.4 42814.4 47845.600000000006 61349.9 43048.2 True False 58648.56186958648 49395.362636885315 57206.75289816201 58056.25741658916 50215.72849980329 56341.163437631796 45031.12013953187 50068.68124495019 54440.028218912645 50489.024011879075 1.1616101324475518 0.9783386310906615 1.1330532530140094 1.149878781632413 0.9945870311929286 1.1159091414477695 0.8918992002883029 0.9916745713517855 1.0782547154427857 1.0 15.623682168904574 -7.23122556734727 24.991275082044638 0.9897632907808481 1.0843631223486516 0.31439521161836304 0.07102308650025163 873.6554372903065 722642.7819014933 0.026744526834255825 0.020713574542444265 5.871842968313064e-08 7.23122556734727 0.0945998315678035 RGS(ph)GDTSSLIDPDTSLSELR ddPTM_PC-9_AZD4547_30min_R2 6 RGSGDTSSLIDPDTSLSELR 20 1 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 RGS(0.603)GDT(0.347)S(0.049)SLIDPDTSLSELR;RGS(0.736)GDT(0.186)S(0.061)S(0.017)LIDPDTSLSELR;RGS(0.817)GDT(0.177)S(0.005)S(0.002)LIDPDTSLSELR;RGS(0.993)GDT(0.006)S(0.001)SLIDPDTSLSELR;RGS(0.616)GDT(0.383)S(0.001)SLIDPDTSLSELR;RGS(0.9)GDT(0.095)S(0.004)S(0.001)LIDPDTSLSELR 171.83 1.6757e-08 270131000.0 101688.40000000001 99050.79999999999 115267.9 123498.3 124512.9 137242.4 109823.7 154650.8 117616.2 111801.40000000001 True False 134023.19594988346 131067.03405603499 113739.37233129198 95027.67496471472 107226.43308410073 128660.61103231266 119597.79654330238 130753.07238184506 123833.15221376876 107887.26701569767 1.2422522106374518 1.2148517399830385 1.0542427802415537 0.8808052849358778 0.9938747736421872 1.1925467628500819 1.1085441299194354 1.2119416498224986 1.1478013637675237 1.0 16.7191650807152 -6.777146778337389 24.98843120256856 1.1439367039835964 1.072665542488771 0.05275640301934703 0.11013958118235535 710.3988709407308 1130145.556535801 0.04283428409340442 0.03790168026011368 1.6705259318928856e-07 6.777146778337389 -0.07127116149482537 RGS(ph)GDTSSLIDPDTSLSELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RGSGDTSSLIDPDTSLSELR 20 1 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 RGS(0.999)GDT(0.001)SSLIDPDTSLSELR;RGS(0.985)GDT(0.008)S(0.007)SLIDPDTSLSELR;RGS(0.935)GDT(0.041)S(0.017)S(0.007)LIDPDTSLSELR;RGS(0.977)GDT(0.022)S(0.001)SLIDPDTSLSELR;RGS(0.876)GDT(0.055)S(0.022)S(0.047)LIDPDTSLSELR 187.18 5.5506e-12 165649600.0 94588.7 114859.6 113495.4 103270.1 123587.0 105460.9 114897.8 104936.3 96655.0 92411.0 True False 110600.69869801748 126262.10200734841 116201.56076970132 97484.21110318144 99371.01452670252 99930.34475069592 104013.84859596427 102181.83331420056 98068.3965217051 109164.38277492649 1.0131573676924677 1.1566236055918875 1.0644640478505154 0.8930038225395636 0.9102878796244761 0.9154116224586808 0.952818547148464 0.9360363766712954 0.8983552513084884 1.0 16.73614269721684 -5.68958071998433 5.712457211885296 0.9264898554572188 1.0897406172004684 0.7080722455203017 0.04369736992050256 0.09549524332838097 5.498159182502879 0.01128530219568895 0.01964662778997048 2.0437100472824047e-06 5.68958071998433 0.1632507617432496 RGS(ph)GDTSSLIDPDTSLSELR ddPTM_PC-9_Lapatinib_30min_R1 6 RGSGDTSSLIDPDTSLSELR 20 1 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 RGS(0.969)GDT(0.023)S(0.008)S(0.001)LIDPDTSLSELR;RGS(1)GDTSSLIDPDTSLSELR;RGS(0.741)GDT(0.085)S(0.085)S(0.085)LIDPDTS(0.004)LSELR;RGS(0.396)GDT(0.014)S(0.014)S(0.014)LIDPDT(0.343)S(0.11)LS(0.11)ELR;RGS(0.884)GDT(0.091)S(0.015)S(0.009)LIDPDTSLSELR;RGS(0.965)GDT(0.004)S(0.016)S(0.016)LIDPDTSLSELR 176.22 1.5455000000000002e-10 93042200.0 79186.8 83925.2 99624.50000000001 93025.7 102096.9 97079.1 97986.59999999999 90009.29999999999 102613.8 88385.70000000001 True False 78057.58171091936 83730.87635574877 91433.75817169085 99867.12030263792 96091.76107222853 92927.25319543514 103059.86669588392 94191.46067310452 91056.35327278209 103663.05047845768 0.7529932926982559 0.8077215166762719 0.8820284349117412 0.9633820328622436 0.9269625062036686 0.8964356418852101 0.994181303947841 0.9086309947311317 0.8783877461883547 1.0 16.661542227887054 -5.24086902560136 1.937120242324395 0.9347053928209202 0.7546146681395309 0.7317060872126191 0.03827606773638857 0.2013298457377221 1.3328064755344855 0.01067701058567292 0.04577214871472017 5.742896301872045e-06 5.24086902560136 -0.1800907246813893 RGS(ph)GEPTPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGSGEPTPQK 10 1 Q9H6A9;Q9H6A9-2 Q9H6A9 PCNXL3 Pecanex-like protein 3 1 RGS(1)GEPTPQK 95.18299999999999 0.008988600000000001 0.0 30077.0 27767.0 84411.0 25288.0 58797.0 23318.0 22625.0 23743.0 24423.0 16394.0 True False 35168.44205217186 30523.52425428994 86423.6783705002 23871.19534480216 47276.14992779609 22095.163031007047 20481.79620918498 23119.77140778796 24780.14017122341 19366.10242516741 1.815979347835544 1.5761315097984194 4.462626318561005 1.2326277544509994 2.4411804135848163 1.1409194553413629 1.0576106518246882 1.193826764942771 1.279562589683515 1.0 14.241246009397617 -6.764909171770601 24.397139493166605 1.1416994525031596 2.325390191766805 0.3403001110880005 0.8151734464251306 79.66849907842897 560167.1553442318 0.2807723940614394 0.25765646291985206 1.7182677076215366e-07 6.764909171770601 1.1836907392636455 RGS(ph)GEPTPQK ddPTM_PC-9_Lapatinib_30min_R1 1 RGSGEPTPQK 10 1 Q9H6A9;Q9H6A9-2 Q9H6A9 PCNXL3 Pecanex-like protein 3 1 RGS(1)GEPTPQK 92.781 0.0033067 7904700.0 79875.0 86074.0 65592.0 22671.0 32676.0 52139.0 28066.0 25392.0 72675.0 14415.0 True False 78735.96785271891 85874.70094137086 60199.27895244202 24338.300968238982 30754.061923487752 49909.13651194531 29519.120152007334 26571.8050180534 64489.576198322735 16906.613543219864 4.657110523727252 5.079355526867744 3.560694091607956 1.439572798302915 1.8190551197534879 2.9520481073491265 1.7460102270951547 1.5716811027900743 3.8144585273367935 1.0 14.045300091120263 -5.527085904064349 3.762090311047478 2.0934648792821324 4.815929905260772 0.684836724886442 0.7725022199411351 0.11971098455338497 3.723908625913402 0.20670375331482177 0.41645130149290877 2.9710782901131116e-06 5.527085904064349 2.7224650259786394 RGS(ph)GPEIFTFDPLPEPAAAPAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RGSGPEIFTFDPLPEPAAAPAGR 23 1 Q5ST79;P46695 Q5ST79 IER3 Radiation-inducible immediate-early gene IEX-1 1 RGS(1)GPEIFTFDPLPEPAAAPAGR;RGS(0.998)GPEIFT(0.002)FDPLPEPAAAPAGR 89.186 0.00033834 0.0 2925.43 5455.4 5410.0 5456.2 5883.9 4214.6 5770.4 5645.299999999999 5846.4 3421.6 True False 3420.6475191237528 5996.976058517426 5538.994917539253 5150.506803239068 4730.992032929566 3993.5789566207336 5223.785937921813 5497.116856689773 5931.892539697854 4041.9089946293007 0.8462950362487005 1.483698931986328 1.3703908041717936 1.2742757964325324 1.1704845505467558 0.9880427693763552 1.2924056293357753 1.3600298433225697 1.4675967587543102 1.0 11.980821123827768 -7.498065823508641 24.35542787557409 1.3135316301850675 1.2074525977367232 0.032484226602230715 0.20284687833310777 1802.8840572072138 1769650.1158055598 0.0854083979586542 0.05724001561794478 3.17639260666547e-08 7.498065823508641 -0.10607903244834427 RGS(ph)GSALGGPLDPQFVGPSDTSLGAAPGHR ddPTM_PC-9_AZD4547_30min_R2 3 RGSGSALGGPLDPQFVGPSDTSLGAAPGHR 30 1 P98174 P98174 FGD1 FYVE, RhoGEF and PH domain-containing protein 1 1 RGS(0.585)GS(0.415)ALGGPLDPQFVGPSDTSLGAAPGHR;RGS(0.624)GS(0.376)ALGGPLDPQFVGPSDTSLGAAPGHR;RGS(0.5)GS(0.5)ALGGPLDPQFVGPSDTSLGAAPGHR 121.02 1.1075e-17 26641300.0 39250.8 44238.4 66662.0 106624.0 93498.0 80905.0 60465.0 87758.0 73000.0 73814.0 True False 51731.73793264227 58537.59767093759 65778.01832382294 82043.48412437853 80517.4165929574 75845.99756029667 65846.26786377397 74197.01757822113 76858.6309675463 71229.79432723291 0.7262654402030745 0.8218133749202364 0.9234621403177964 1.1518141375990367 1.1303895701713909 1.0648071958744778 0.9244203003208633 1.0416570520666768 1.079023626187298 1.0 16.120193204127247 -5.36031266986239 2.43913083830714 1.0549700177927765 0.7557451514434937 0.7522821165648711 0.06463012002414109 0.15491594632120034 1.75481334155484 0.01951890444980279 0.05602415898783871 4.362016762206219e-06 5.36031266986239 -0.2992248663492828 RGS(ph)GSALGGPLDPQFVGPSDTSLGAAPGHR ddPTM_PC-9_Lapatinib_30min_R1 2 RGSGSALGGPLDPQFVGPSDTSLGAAPGHR 30 1 P98174 P98174 FGD1 FYVE, RhoGEF and PH domain-containing protein 1 1 RGS(0.714)GS(0.286)ALGGPLDPQFVGPSDTSLGAAPGHR;RGS(0.564)GS(0.435)ALGGPLDPQFVGPS(0.001)DTSLGAAPGHR 107.87 1.8431e-15 11938500.0 23168.3 15398.9 21193.4 19430.6 25341.1 23351.8 15315.8 18691.3 23452.7 16149.4 True False 22837.915793454144 15363.24479315559 19450.960460889804 20859.591142581463 23850.586320519502 22353.097949704537 16108.777183215054 19559.76603394539 20811.20995812042 18940.80227227713 1.205752294182441 0.8111190102882884 1.026934349521159 1.1013045193504176 1.2592173223532679 1.1801558153860168 0.8504801935867735 1.0326788566170828 1.0987501827512833 1.0 14.209209819633609 -10.837603044289164 13.99818554291044 1.0000000000334048 1.0576784503213952 0.017476250615729105 0.13653844173537943 0.0 0.0 0.13751081837201723 0.033351272283114866 1.4534394896571664e-11 10.837603044289164 0.057678450287990346 RGS(ph)GSPEDTPR ddPTM_PC-9_Lapatinib_30min_R1 1 RGSGSPEDTPR 11 1 Q96HP0 Q96HP0 DOCK6 Dedicator of cytokinesis protein 6 1 RGS(0.728)GS(0.227)PEDT(0.046)PR 96.37100000000001 0.0085679 2067300.0 13531.0 12852.0 12095.0 8542.5 11831.0 10092.0 10202.0 8845.1 10173.0 7236.8 True False 13338.045458718509 12822.241983624534 11100.595788050166 9170.743946944622 11135.123840640941 9660.388685601029 10730.209641230618 9256.075636625084 9027.209613560879 8487.671237570134 1.5714611329051607 1.5106902264154272 1.3078494061968482 1.0804782242685025 1.311917430466914 1.138167162135114 1.264211270782265 1.09053182876048 1.0635673037855795 1.0 13.051153060482042 -1.5228787452814374 0.32380078821873426 1.0707120370931653 6.4644240584350205 0.781625279295469 0.08616873843656143 26.836475011163607 0.3827327465983555 0.08220556277109636 86.06277361332234 0.029999999999924025 1.5228787452814374 5.393712021341855 RGS(ph)GVFCANCLTTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGSGVFCANCLTTK 14 1 Q9UHF7;Q9UHF7-3;Q9UHF7-2;E5RFF3;H0YAV4 Q9UHF7 TRPS1 Zinc finger transcription factor Trps1 1 RGS(1)GVFCANCLTTK 86.573 0.0029561 3767900.0 32897.0 24189.0 22893.0 28632.0 32215.0 27673.0 28665.0 25022.0 21593.0 17831.0 True False 38465.812354633024 26590.324060468167 23438.85594218598 27027.841866196435 25902.702007312473 26221.779164467705 25949.64368337183 24365.19901300046 21908.75677505741 21063.619149881666 1.8261729895951486 1.2623815438012014 1.1127648945512603 1.2831527988554747 1.229736534020935 1.2448847929637494 1.2319651005234593 1.1567432376946172 1.0401230965657908 1.0 14.362465720993637 -4.763986832314376 3.8521084239678025 1.1801722236376562 1.902016486576277 0.8345728446206417 0.08787686197150224 0.10010702877482157 2.6577276115996398 0.021876303203041424 0.21051089463554232 1.721920782344723e-05 4.763986832314376 0.7218442629386208 RGS(ph)IGENQGEEK ddPTM_PC-9_AZD4547_30min_R2 3 RGSIGENQGEEK 12 1 E7EX44;Q05682-3;Q05682-6;Q05682-2 E7EX44 CALD1 Caldesmon 1 RGS(1)IGENQGEEK;RGS(1)IGENQGEEK;RGS(1)IGENQGEEK 135.61 2.793e-05 38369900.0 86293.0 80862.0 109560.0 110140.0 114873.0 103459.0 103793.0 104185.0 94091.0 100943.0 True False 113732.378994097 106999.0601574052 108107.16281476762 84748.92464603699 98924.86680231451 96989.69237489319 113030.37592631605 88085.60218312817 99064.45816941641 97409.01629465801 1.1675754803853222 1.0984512956556067 1.1098270666007775 0.8700316240713817 1.0155617063524296 0.9956952247777928 1.1603687238192009 0.9042859227391546 1.0169947499495402 1.0 16.571767695610298 -5.556796693070933 24.93626676525118 0.9978685532066294 1.1257949531051006 0.39690749568863093 0.07395113804424575 177.20528916528656 130279.44868810648 0.02002443310193241 0.034683606653452784 2.7746186870939404e-06 5.556796693070933 0.1279263998984712 RGS(ph)IGENQGEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RGSIGENQGEEK 12 1 E7EX44;Q05682-3;Q05682-6;Q05682-2 E7EX44 CALD1 Caldesmon 1 RGS(1)IGENQGEEK;RGS(1)IGENQGEEK;RGS(1)IGENQGEEK;RGS(1)IGENQGEEK 118.21 0.00027288 39769500.0 136071.0 153380.0 136415.0 163155.0 172798.0 157152.0 183803.0 140684.0 138264.0 112066.0 True False 159105.1327752462 168606.55274689314 139667.6509567686 154013.95430564668 138939.47234082205 148910.67246971524 166391.84922151727 136991.19406701904 140285.84943021048 132382.67868603187 1.2018576323915546 1.2736300127811462 1.0550296484634087 1.1633995915048454 1.0495290903603842 1.1248501235035615 1.2569004561098507 1.0348120722947225 1.0596994321509563 1.0 17.01435484274107 -1.5228787670861186 0.07998532574589667 0.8936345490962053 1.7344978848671646 0.3609332248385776 0.07387284859247586 234.84999961375942 1.374790087985486 2.183452756328549 21.83288002375125 0.02999999849371005 1.5228787670861186 0.8408633357709593 RGS(ph)IGENQGEEK ddPTM_PC-9_Lapatinib_30min_R1 4 RGSIGENQGEEK 12 1 E7EX44;Q05682-3;Q05682-6;Q05682-2 E7EX44 CALD1 Caldesmon 1 RGS(1)IGENQGEEK;RGS(1)IGENQGEEK;RGS(1)IGENQGEEK;RGS(1)IGENQGEEK 97.904 0.0017535999999999997 46754300.0 101810.0 107973.0 121279.0 108148.0 120447.0 105090.0 91882.0 94922.0 121617.0 99188.0 True False 100358.17073033264 107722.99515234116 111307.90877047855 116101.56469115234 113362.54426791296 100595.54567675505 96639.20037792111 99332.42264979762 107919.21277621487 116332.51364029762 0.8626837638928876 0.9259921562893649 0.9568082497954505 0.9980147514919226 0.9744699974285103 0.864724250589121 0.830715312115849 0.8538663830211336 0.9276788526198545 1.0 16.827894844781724 -6.767233606456255 24.997745520921843 0.8822210006071651 0.9463734410467226 0.13771168702536762 0.05539472651884703 216.01498213454963 931936.4236921768 0.01964439153986859 0.01778164268445857 1.7090957473397626e-07 6.767233606456255 0.06415244043955748 RGS(ph)IGENQIK ddPTM_PC-9_AZD4547_30min_R2 1 RGSIGENQIK 10 1 Q05682-5;E9PGZ1;Q05682-4;C9J813 Q05682-5 CALD1 Caldesmon 1 RGS(1)IGENQIK 103.11 0.004344300000000001 9115600.0 21492.0 23270.0 22137.0 17373.0 25705.0 22109.0 25913.0 28722.0 27083.0 21663.0 True False 28326.008938629206 30791.572430348227 21843.44891594114 13367.923260174337 22136.304450597545 20726.52073494345 28219.20679986732 24283.67486590013 28514.55208895966 20904.584963704012 1.3550141745368676 1.472957845554489 1.0449118676054678 0.6394732678684916 1.0589210208684903 0.9914820490782414 1.3499051451565989 1.1616434819472918 1.364033399298221 1.0 14.351531780178574 -5.264652322442167 24.847775631484765 1.0725905512319034 1.4139860256831258 0.3259277671638593 0.19419568451636024 293.924842286663 2273133.962174858 0.05504720943459815 0.12280020731950228 5.436854085647752e-06 5.264652322442167 0.3413954744512224 RGS(ph)IGENQIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RGSIGENQIK 10 1 Q05682-5;E9PGZ1;Q05682-4;C9J813 Q05682-5 CALD1 Caldesmon 1 RGS(1)IGENQIK;RGS(1)IGENQIK;RGS(1)IGENQIK 131.79 7.697800000000001e-05 24358600.0 95432.0 136357.0 106177.0 102784.0 108436.0 87790.0 115973.0 76234.0 81274.0 71789.0 True False 111586.75273208314 149893.62180798102 108708.66235851501 97025.34571022404 87188.74421433908 83186.1378545376 104987.19786819044 74232.93827659955 82462.47849469827 84803.77741858875 1.3158229046955594 1.7675347298282582 1.2818846715038708 1.1441158479451925 1.0281233556847145 0.9809249114450819 1.2380014318227472 0.8753494306059991 0.972391572696887 1.0 16.371840907801264 -5.645587467495454 2.3471360942598505 1.025643886925746 1.5428989811958809 0.6834779375243878 0.1384794425531836 0.15449223674440715 1.7169293388279774 0.03878482013440846 0.08054837015340244 2.261583008025244e-06 5.645587467495454 0.5172550942701348 RGS(ph)IGENQIK ddPTM_PC-9_Lapatinib_30min_R1 3 RGSIGENQIK 10 1 Q05682-5;E9PGZ1;Q05682-4;C9J813 Q05682-5 CALD1 Caldesmon 1 RGS(1)IGENQIK;RGS(1)IGENQIK;RGS(1)IGENQIK 155.88 0.00013765 38955400.0 95570.0 109344.0 108174.0 103301.0 122124.0 106893.0 118822.0 113981.0 111647.0 108295.0 True False 94207.15427460826 109090.82068607541 99280.35128371534 110898.10014203387 114940.90642502207 102321.43556975342 124974.02175948878 119276.9733680978 99072.13916496916 127013.6464559831 0.7417089179252561 0.8588905501888816 0.7816510591885195 0.8731195681439309 0.9049492683044505 0.8055940320177578 0.9839416885239874 0.939087859424881 0.7800117698321721 1.0 16.954623984164208 -1.5228787452803376 0.12884553614757752 1.000670214891851 0.2640484946871252 0.38961564679538374 0.06648804746044866 91.78325634308881 0.8048112366645972 0.3632857393523101 12.258562680930908 0.029999999999999995 1.5228787452803376 -0.7366217202047257 RGS(ph)LEMSSDGEPLSR ddPTM_PC-9_AZD4547_30min_R2 1 RGSLEMSSDGEPLSR 15 1 Q6ZN18-2;Q6ZN18 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 RGS(0.477)LEMS(0.261)S(0.261)DGEPLS(0.002)R 101.04 0.0037433999999999996 0.0 4811.0 4563.7 5673.9 7738.0 7804.1 6699.7 4980.1 5155.3 4571.8 5266.9 True False 6340.797924983483 6038.8267769823915 5598.660378739595 5954.123650908253 6720.6354235716135 6280.766699891476 5423.319252267943 4358.666842008737 4813.456014485317 5082.507434119591 1.2475727792185427 1.1881589658763494 1.1015547839940176 1.171493348133124 1.3223070523133988 1.2357614388771574 1.0670558425277321 0.8575819904853242 0.9470632511370087 1.0 12.311324704945498 -7.50645311623595 3.792413492075669 0.9282407640376018 1.206904449280386 0.7944560967234393 0.06312051427088147 0.10340458777957853 3.2698548069985307 0.03273946765119792 0.019482332730905005 3.115637222872281e-08 7.50645311623595 0.2786636852427842 RGS(ph)LEMSSDGEPLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RGSLEMSSDGEPLSR 15 1 Q6ZN18-2;Q6ZN18 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 RGS(0.998)LEMS(0.002)S(0.001)DGEPLSR;RGS(0.983)LEMS(0.009)S(0.009)DGEPLSR 105.53 0.00099814 46594000.0 44549.0 46243.0 46314.0 59969.0 58669.0 64345.0 52681.0 48450.0 51168.0 41376.0 True False 52090.26581714275 50833.69943065979 47418.301406823106 56609.1313521212 47173.23060894044 60970.63492710128 47690.67430258889 47178.23883701834 51916.235199654446 48877.14126776424 1.0657387986702416 1.0400301268066583 0.9701529217318756 1.1581923550315414 0.9651389051276701 1.2474263703984878 0.9757255245621771 0.965241370778238 1.0621782259163053 1.0 15.576872286649053 RGS(ph)LEMSSDGEPLSR ddPTM_PC-9_Lapatinib_30min_R1 4 RGSLEMSSDGEPLSR 15 1 Q6ZN18-2;Q6ZN18 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 RGS(1)LEMSSDGEPLSR;RGS(1)LEMSSDGEPLSR;RGS(0.9)LEMS(0.05)S(0.05)DGEPLSR;RGS(1)LEMSSDGEPLSR 182.7 6.0782000000000005e-06 39686700.0 60350.0 58955.0 74518.0 64750.3 72749.0 67955.0 63176.7 57349.899999999994 77819.0 58270.899999999994 True False 59489.39793316542 58818.49331968441 68391.41768779853 69512.25306266872 68470.04685003702 65048.72306084202 66447.68040003286 60014.58572010319 69054.2047496012 68342.94742390631 0.8704540874448161 0.8606373523057881 1.0007092211518414 1.0171093826479216 1.0018597299490517 0.9517986202346319 0.9722682867023892 0.8781386811993147 1.0104071795628482 1.0 16.060504847716963 -5.254912832198429 24.641534980291965 0.9756445721728978 0.8655457017272333 0.5781123038125839 0.038693721659737106 314.9862042610006 1189246.8767046274 0.010430731185240115 0.02623140771859737 5.560158447237635e-06 5.254912832198429 -0.11009887044566447 RGS(ph)LGEEGSEPPPPPPLPLAR ddPTM_PC-9_AZD4547_30min_R2 1 RGSLGEEGSEPPPPPPLPLAR 21 1 Q14934-2;Q14934-9;Q14934-4;Q14934-6;Q14934;Q14934-12;Q14934-3;Q14934-5;Q14934-7;Q14934-8;Q14934-11;Q14934-13;Q14934-14;Q14934-15;Q14934-16;Q14934-17;Q14934-18;Q14934-10 Q14934-2 NFATC4 Nuclear factor of activated T-cells, cytoplasmic 4 1 RGS(0.991)LGEEGS(0.009)EPPPPPPLPLAR 98.06700000000001 0.00012383 3611400.0 4059.8 10819.0 11839.0 18584.0 16877.0 13659.0 11563.0 12500.0 14572.0 14539.0 True False 5350.731950914145 14316.030172923834 11682.007124534824 14299.745919937837 14533.919868225435 12804.900570744607 12592.084599500871 10568.412221424403 15342.24617067239 14029.994035327192 0.381378063129687 1.020387473927388 0.8326451953664277 1.0192267996644486 1.0359177510431843 0.9126804001842175 0.8975117571535883 0.7532727522772563 1.093531909710081 1.0 13.776226775164018 -4.756555551124977 24.999827797932276 0.9420867895356391 0.38137720710961515 0.7493137288733376 0.09882071468873047 74.60414255588336 381846.8115802183 0.024087050432041658 0.19322719085891296 1.7516383657266478e-05 4.756555551124977 -0.560709582426024 RGS(ph)LGEEGSEPPPPPPLPLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGSLGEEGSEPPPPPPLPLAR 21 1 Q14934-2;Q14934-9;Q14934-4;Q14934-6;Q14934;Q14934-12;Q14934-3;Q14934-5;Q14934-7;Q14934-8;Q14934-11;Q14934-13;Q14934-14;Q14934-15;Q14934-16;Q14934-17;Q14934-18;Q14934-10 Q14934-2 NFATC4 Nuclear factor of activated T-cells, cytoplasmic 4 1 RGS(0.949)LGEEGS(0.051)EPPPPPPLPLAR 96.777 0.00056639 0.0 4721.8 5858.2 5020.0 7157.3 9659.5 4709.4 5635.5 5437.1 6871.7 4533.4 True False 5521.107480198993 6439.763380504966 5139.695838456015 6756.29968527968 7766.790316300948 4462.430773575116 5101.664642513234 5294.381886083642 6972.185612520822 5355.2695336253455 1.030967245538691 1.2025096664267154 0.9597455004242533 1.2616171124268103 1.45030801298307 0.8332784644275774 0.9526438604967042 0.9886303299657665 1.3019299157106807 1.0 12.386743473090249 -6.785607742816548 24.99999391038082 1.0106702451691298 1.1744066845781436 0.2011357863135731 0.1647538366662599 417.7619482237786 432133.9776686921 0.06009294468232412 0.05302281812964986 1.638295571025571e-07 6.785607742816548 0.16373643940901372 RGS(ph)LGEEGSEPPPPPPLPLAR ddPTM_PC-9_Lapatinib_30min_R1 2 RGSLGEEGSEPPPPPPLPLAR 21 1 Q14934-2;Q14934-9;Q14934-4;Q14934-6;Q14934;Q14934-12;Q14934-3;Q14934-5;Q14934-7;Q14934-8;Q14934-11;Q14934-13;Q14934-14;Q14934-15;Q14934-16;Q14934-17;Q14934-18;Q14934-10 Q14934-2 NFATC4 Nuclear factor of activated T-cells, cytoplasmic 4 1 RGS(0.999)LGEEGS(0.001)EPPPPPPLPLAR;RGS(0.888)LGEEGS(0.112)EPPPPPPLPLAR 111.24 1.2703e-05 7277300.0 17157.4 16222.2 14734.7 10784.099999999999 13383.900000000001 13698.4 16177.0 18469.5 13869.400000000001 9179.8 True False 16912.732329718194 16184.638492589 13523.269843586824 11577.198688703005 12596.68531575982 13112.551364530038 17014.565905331092 19327.660396224674 12307.282120743255 10766.516198685375 1.5708639654286027 1.5032382057406086 1.2560488085494228 1.0752966396053552 1.1699871233461678 1.2179010482639798 1.5803223244496325 1.7951638245419295 1.1431071939729225 1.0 13.394263881432263 -7.2465611552318565 24.648678413842685 1.4459120017063152 1.2902081013189024 0.0 0.24935035338870268 1906.4458625575587 3158403.401611935 0.09806008872368481 0.07560305321318819 5.6681175023570726e-08 7.2465611552318565 -0.15570390038741277 RGS(ph)LPAGASWQNTDLFEMIEK ddPTM_PC-9_AZD4547_30min_R2 1 RGSLPAGASWQNTDLFEMIEK 21 1 J3KPC5;P47736-3 J3KPC5 RAP1GAP Rap1 GTPase-activating protein 1 1 RGS(0.983)LPAGAS(0.017)WQNTDLFEMIEK 91.556 0.00015373 7295100.0 22849.0 21247.0 22248.0 33436.0 36434.0 22021.0 20108.0 23955.0 27285.0 26253.0 True False 30114.506711275757 28114.677242269383 21952.976983415036 25727.84678105045 31375.76799661821 20644.023388854752 21897.57304564242 20253.30518113771 28727.229396568502 25333.890460791277 1.188704386240374 1.1097654853202223 0.8665458239582741 1.0155505653925871 1.2384899210477687 0.8148777393983394 0.8643588745097335 0.7994549914267342 1.1339446438765108 1.0 14.628781024602254 -6.779433525360423 24.99964261734413 0.9063576809674281 1.0693906390061934 0.26866762725734006 0.13062569611882496 346.43358160081175 481304.2789147992 0.04701238304058449 0.0415451893890248 1.6617530120571886e-07 6.779433525360423 0.16303295803876527 RGS(ph)LPAGASWQNTDLFEMIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGSLPAGASWQNTDLFEMIEK 21 1 J3KPC5;P47736-3 J3KPC5 RAP1GAP Rap1 GTPase-activating protein 1 1 RGS(0.832)LPAGAS(0.165)WQNT(0.003)DLFEMIEK 59.56100000000001 0.0041985 9443600.0 60928.0 56622.0 47974.0 59339.0 61941.0 59129.0 44078.0 47035.0 40503.0 44379.0 True False 71241.90701714682 62243.057958238394 49117.88210240816 56014.42820963365 49804.10569718898 56028.171149344504 39902.61274291516 45800.381087701884 41095.27975085218 52424.56139602929 1.358941403037523 1.187288101240133 0.9369249984059651 1.0684768115938164 0.9500147329980563 1.0687389585597593 0.7611434732182125 0.8736435721743753 0.78389363032353 1.0 15.677955265782229 -1.5228787452808885 0.43435944841086066 0.8726348268816361 10.969642575903165 0.7025027108078838 0.094395432899548 44.81925056934118 0.5583420565241487 0.06179831506508602 397.2209027984163 0.029999999999961943 1.5228787452808885 10.097007749021529 RGS(ph)LPDQK ddPTM_PC-9_AZD4547_30min_R2 3 RGSLPDQK 8 1 X6RKU3;Q6P3S6 X6RKU3 FBXO42 F-box only protein 42 1 RGS(1)LPDQK;RGS(1)LPDQK;RGS(1)LPDQK 84.605 0.0063495 103724600.0 160270.0 147199.0 175470.0 236376.0 217230.0 193482.0 169313.0 201114.0 166783.0 186645.0 True False 211232.52617690727 194778.19811666664 173143.15314993894 181883.16517279527 187071.3641627428 181383.5399537895 184381.52899725776 170036.45243996396 175598.80888575732 180110.6153603162 1.1727933178970646 1.08143652569843 0.9613156492945256 1.0098414510934461 1.0386470769005005 1.0070674601323568 1.0237127258068464 0.9440668008368157 0.9749498025669786 1.0 17.45852368775411 -4.959957155121618 2.983404971397141 0.9967119976112547 1.1748607179655703 0.8058154979861016 0.027650474321409543 0.12751357439912142 2.08312128204153 0.007761961861586401 0.044755540698736045 1.0965863734152963e-05 4.959957155121618 0.17814872035431562 RGS(ph)LPDQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RGSLPDQK 8 1 X6RKU3;Q6P3S6 X6RKU3 FBXO42 F-box only protein 42 1 RGS(1)LPDQK;RGS(1)LPDQK;RGS(1)LPDQK;RGS(1)LPDQK;RGS(1)LPDQK 93.561 0.0032696999999999995 96984200.0 209748.0 218676.0 210194.0 278217.0 265478.0 231250.0 245402.0 252481.0 210623.0 167705.0 True False 245254.19368816493 240384.70810066347 215205.82212518365 262629.4034816835 213459.49164976887 219122.84290764117 222155.74600337708 245853.64127573228 213702.96291543156 198108.58894795008 1.2379786004765378 1.2133987192439233 1.0863023318071565 1.3256840850584488 1.0774873153321585 1.1060744214639389 1.1213837178041028 1.2410044540791034 1.0787162941813626 1.0 17.595931903700055 -14.522878744922139 0.09546047821216609 0.47421994943827983 1.2869766425313343 0.3589583167011643 0.07618275714276358 235.92407025749517 1.541628741197682 24.965416882432653 1.4889639535660526 3.000000002474351e-15 14.522878744922139 0.8127566930930544 RGS(ph)LPDQK ddPTM_PC-9_Lapatinib_30min_R1 4 RGSLPDQK 8 1 X6RKU3;Q6P3S6 X6RKU3 FBXO42 F-box only protein 42 1 RGS(1)LPDQK;RGS(1)LPDQK;RGS(1)LPDQK;RGS(1)LPDQK 109.16 0.001734 110879900.0 277806.0 273807.0 300188.0 275043.0 268590.0 248231.0 246328.0 243315.0 271110.0 223347.0 True False 273844.43549661955 273173.01671415137 275507.70139918994 295270.5797365519 252792.06426825738 237614.73878472377 259081.65854783906 254620.3031650775 240574.73688513582 261952.23135882875 1.045398369298487 1.0428352348713232 1.0517478700984706 1.127192458735283 0.9650311545618272 0.9070918676742751 0.9890416172593792 0.9720104381027097 0.9183916305549255 1.0 17.998944225646326 -6.365590300395045 7.453674317032859 0.9554132874767188 1.063780912052186 0.69910842982597 0.034750808629149754 0.15345538687772742 9.703846336740684 0.010793888258488545 0.012240057139803091 4.30932947239032e-07 6.365590300395045 0.10836762457546711 RGS(ph)LPDTGWK ddPTM_PC-9_AZD4547_30min_R2 1 RGSLPDTGWK 10 1 O75096 O75096 LRP4 Low-density lipoprotein receptor-related protein 4 1 RGS(1)LPDTGWK 118.73 0.0003891 3320600.0 19346.0 24565.0 22743.0 22811.0 19857.0 17697.0 19755.0 28397.0 17578.0 14685.0 True False 25497.625578202133 32505.155855242992 22441.412959987796 17552.276376436836 17100.198306769707 16590.403792405537 21513.156729494025 24008.89614814308 18507.13719380177 14170.882619766118 1.799296928946191 2.2937989628044404 1.5836284557664466 1.2386156069032859 1.2067137076499146 1.1707389184964792 1.518123980470109 1.6942414098225969 1.3059974943259545 1.0 13.790641997473978 -5.466836692264218 4.603624551837362 1.3362325279665668 2.0392555553490803 0.6536117275630298 0.21314603823975067 0.13012074825167116 5.7022674705874765 0.05852245642417504 0.12310207452122618 3.413212345032612e-06 5.466836692264218 0.7030230273825135 RGS(ph)LPDTGWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RGSLPDTGWK 10 1 O75096 O75096 LRP4 Low-density lipoprotein receptor-related protein 4 1 RGS(1)LPDTGWK;RGS(0.994)LPDT(0.006)GWK 87.831 0.014506 0.0 39008.0 44761.0 41509.0 40225.0 64174.0 42132.0 40660.0 32365.0 38054.0 34802.0 True False 45611.28395688133 49204.5762648566 42498.731983759135 37971.323661209564 51599.5653769136 39922.52375085292 36808.39044709221 31515.4530435521 38610.46775890496 41111.32710751957 1.109457834761522 1.1968617830353794 1.0337475088705126 0.9236219390802474 1.2551179688742191 0.9710833135219025 0.8953345230336697 0.7665880734311709 0.9391686057208991 1.0 15.327248323587867 -6.992578765330203 24.472145599493775 0.8883056565666477 1.0968427150299442 0.48354347065209136 0.09956289188922672 117.86626578434274 388670.8100483333 0.03554440720867496 0.03127985274828853 1.0172348597935842e-07 6.992578765330203 0.2085370584632965 RGS(ph)LSNAGDPEIVK ddPTM_PC-9_AZD4547_30min_R2 5 RGSLSNAGDPEIVK 14 1 F5H7V1;O43847;O43847-2 F5H7V1 NRD1 Nardilysin 1 RGS(0.996)LS(0.004)NAGDPEIVK;RGS(0.905)LS(0.095)NAGDPEIVK;RGS(0.996)LS(0.004)NAGDPEIVK;RGS(0.999)LS(0.001)NAGDPEIVK;RGS(0.994)LS(0.006)NAGDPEIVK 142.4 9.8306e-05 519840000.0 438307.0 486276.0 505474.0 416763.0 423886.0 489205.0 500531.0 565983.0 483014.0 461262.0 True False 577679.5086480445 643455.2073545352 498771.084489156 320684.72927416326 365036.74570496014 458614.934015018 545077.2893429701 478523.3323454767 508545.1339473757 445113.35777722625 1.2978255955579883 1.4455985112821006 1.1205484530499865 0.7204563144893575 0.8200983846628492 1.0303328938614984 1.224580839507797 1.0750594741418023 1.1425070154868195 1.0 18.763813270912898 -5.424296529438661 4.93620376659912 1.0021138466361517 1.3647898625302675 0.5143432685990647 0.14157073120660008 0.19245749360367556 7.386442913482239 0.0424555676006161 0.09075009008817213 3.764466793459718e-06 5.424296529438661 0.3626760158941158 RGS(ph)LSNAGDPEIVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RGSLSNAGDPEIVK 14 1 F5H7V1;O43847;O43847-2 F5H7V1 NRD1 Nardilysin 1 RGS(0.981)LS(0.019)NAGDPEIVK;RGS(0.905)LS(0.095)NAGDPEIVK;RGS(1)LSNAGDPEIVK;RGS(0.924)LS(0.076)NAGDPEIVK;RGS(0.977)LS(0.023)NAGDPEIVK 211.45 2.7713e-11 547474000.0 697817.0 940443.0 732249.0 679683.0 687891.0 544753.0 688807.0 530734.0 540772.0 473598.0 True False 815943.6355860109 1033803.965868736 749708.5932297958 641602.565072016 553103.6966168615 516185.1936971508 623558.2144291752 516802.7948591545 548679.7674598886 559457.5684002937 1.4584549064536037 1.8478684072945564 1.3400633677608538 1.1468297174111106 0.9886427994859371 0.9226529818393995 1.1145764212506235 0.9237569103531734 0.9807352665346488 1.0 19.09366918976744 -5.654174847176423 2.118317901698132 0.9929520724100589 1.6547752758622327 0.8482310040281752 0.1098170271946312 0.10161110249975269 0.9204798502850007 0.030484849894015287 0.06561787623518621 2.2173035525545716e-06 5.654174847176423 0.6618232034521738 RGS(ph)LSNAGDPEIVK ddPTM_PC-9_Lapatinib_30min_R1 4 RGSLSNAGDPEIVK 14 1 F5H7V1;O43847;O43847-2 F5H7V1 NRD1 Nardilysin 1 RGS(1)LSNAGDPEIVK;RGS(0.994)LS(0.006)NAGDPEIVK;RGS(0.999)LS(0.001)NAGDPEIVK;RGS(0.961)LS(0.039)NAGDPEIVK 192.23 1.1628000000000001e-06 531221000.0 587961.0 849460.0 797983.0 745750.0 878930.0 784190.0 799793.0 764943.0 805258.0 662010.0 True False 579576.5683211589 847493.1275606656 732375.9180434599 800594.9427490706 827233.065442866 750652.0217361745 841202.3681227958 800485.044341716 714561.3642973365 776437.5464271227 0.746456132870126 1.0915148700117792 0.9432515485805419 1.031113122276365 1.065421255385556 0.9667899565011976 1.0834127895974337 1.0309715804255615 0.9203075863415965 1.0 19.566510359019148 -4.751477436054032 24.995921865674866 1.0162283861432408 0.7464555845738543 0.681454659211562 0.05502237424759318 227.97372876026557 571979.1778368019 0.013011046020057562 0.17127074710083795 1.772240120197506e-05 4.751477436054032 -0.26977280156938654 RGS(ph)LSQEMAK ddPTM_PC-9_AZD4547_30min_R2 1 RGSLSQEMAK 10 1 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 RGS(0.818)LS(0.182)QEMAK 84.17299999999999 0.004732500000000001 2396600.0 25526.0 23691.0 26298.0 29423.0 27430.0 26147.0 19782.0 28920.0 24063.0 24846.0 True False 33642.73702621667 31348.65244724452 25949.271337192033 22639.98193081851 23621.81797626496 24512.023956604382 21542.559677188114 24451.078515487497 25334.921054411865 23976.149102533833 1.4031751672190453 1.307493222251089 1.0822952103867955 0.9442709850526366 0.9852215164014213 1.0223503303962151 0.8984995707634912 1.0198084108887808 1.0566718177330001 1.0 14.5493123403528 -5.259677059731599 2.2660904058635283 0.9875424495796348 1.3971734562748583 0.9208769425846757 0.04264051361360192 0.081576134491256 0.7794176395945938 0.012068805327571853 0.04338803609160244 5.499496630174195e-06 5.259677059731599 0.40963100669522357 RGS(ph)LSQEMAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGSLSQEMAK 10 1 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 RGS(0.79)LS(0.21)QEMAK 53.376999999999995 0.037153 2892100.0 32404.0 36346.0 24617.0 26386.0 38255.0 28274.0 43059.0 31921.0 27372.0 27544.0 True False 37889.35719182687 39954.19067765416 25203.962640492373 24907.677964566214 30759.207365815266 26791.261666467664 38980.1397998363 31083.107573095203 27772.263717263555 32537.509161815986 1.1644824133093594 1.2279425102564991 0.7746125407187034 0.7655065985750479 0.9453460992617214 0.823396208149462 1.198006264277322 0.9553007705203329 0.8535460898111823 1.0 14.989816192408714 -5.247007951116435 24.7128284007216 0.9155249871061484 1.1962125173262255 0.46502238584894406 0.12087500134524719 638.6120493050299 1093574.0769376683 0.03255961586162475 0.08526593549843127 5.662289223550659e-06 5.247007951116435 0.2806875302200771 RGS(ph)LTLTIS(ph)GESPK ddPTM_PC-9_AZD4547_30min_R2 1 RGSLTLTISGESPK 14 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 2 RGS(0.742)LT(0.255)LT(0.258)IS(0.739)GES(0.006)PK 66.325 0.027832 3448800.0 37360.0 35060.0 30816.0 29993.0 23079.0 28871.0 28501.0 30577.0 34509.0 28272.0 True False 49239.70286372544 46392.45936433214 30407.359705183277 23078.5772372307 19874.879222538057 27065.691805986353 31037.533786247015 25852.027239559517 36333.07528848019 27282.20588532705 1.8048285050956088 1.7004658479350818 1.1145491619333099 0.845920499765851 0.7284923845995601 0.9920639086058234 1.1376475170924378 0.9475783354257027 1.331749912056081 1.0 14.735672676813381 -5.276361218041277 3.3542778880255915 0.9888589538156453 1.7865897549120846 0.7939191274515799 0.15217794394212178 0.1025321678257329 2.4163564366997394 0.04302287207649844 0.11716765235066644 5.292230872758002e-06 5.276361218041277 0.7977308010964393 RGS(ph)LTLTISGESPK ddPTM_PC-9_AZD4547_30min_R2 4 RGSLTLTISGESPK 14 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RGS(0.993)LT(0.006)LT(0.001)IS(0.001)GESPK;RGS(0.983)LT(0.016)LT(0.001)ISGESPK;RGS(0.934)LT(0.051)LT(0.015)ISGESPK;RGS(0.999)LT(0.001)LTISGESPK 128.74 3.636e-05 127430800.0 99925.0 95654.0 115406.0 147534.0 139509.0 111667.0 104963.0 121203.0 110022.0 118801.0 True False 131699.07143088238 126572.28488407942 113875.64103505909 113522.31567757795 120140.58345062898 104684.44483734827 114304.50365972558 102473.86131786404 115837.53830563542 114641.8131502099 1.1487874084678262 1.1040673677957062 0.9933168178860977 0.9902348240849512 1.047964788320421 0.9131436598982001 0.9970577097376997 0.8938611358457603 1.0104300963371786 1.0 16.806773806683793 -4.57663895738871 0.7442151423222311 0.9655606066604924 1.330858587994924 0.6426566720440186 0.04366586851654499 2.136017505635055 0.7307524679687698 0.016809293094234536 0.6998718668769354 2.6507028352203617e-05 4.57663895738871 0.3652979813344316 RGS(ph)LTLTISGESPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 RGSLTLTISGESPK 14 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RGS(0.988)LT(0.01)LT(0.002)ISGESPK;RGS(0.907)LT(0.084)LT(0.008)ISGESPK;RGS(0.886)LT(0.094)LT(0.02)ISGESPK;RGS(0.867)LT(0.127)LT(0.007)ISGESPK;RGS(0.855)LT(0.121)LT(0.019)IS(0.005)GESPK;RGS(0.994)LT(0.006)LTISGESPK;RGS(0.913)LT(0.08)LT(0.006)ISGESPK;RGS(1)LTLTISGESPK 147.7 0.00030434 173563500.0 362718.0 354417.0 363103.4 435490.0 471989.0 394781.0 381291.0 406421.0 376897.0 294452.0 True False 424118.99339294597 389601.17749964586 371761.1621333126 411090.9071776304 379506.1436513858 374077.98938776826 345172.35617221455 395752.8793886441 382408.4056059279 347833.81671925116 1.2193150090845457 1.1200784937311217 1.0687895893497155 1.181860093578642 1.0910559163880793 1.0754503196844132 0.9923484709677186 1.1377642436303717 1.0993997340821613 1.0 18.408038674020695 -6.480557081925122 4.8701754322868505 1.066661759251888 1.1401108356302438 0.35395574878103 0.054510096032608334 0.27824159804550413 15.43998018728409 0.017745189243034518 0.019554331455117327 3.3070664244767626e-07 6.480557081925122 0.07344907637835574 RGS(ph)LTLTISGESPK ddPTM_PC-9_Lapatinib_30min_R1 4 RGSLTLTISGESPK 14 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RGS(0.823)LT(0.168)LT(0.008)IS(0.001)GESPK;RGS(0.959)LT(0.038)LT(0.003)ISGESPK;RGS(0.885)LT(0.078)LT(0.037)ISGESPK;RGS(0.9)LT(0.099)LT(0.001)ISGESPK 100.45 0.00089597 139511000.0 458449.0 354348.0 410754.0 359141.0 357746.0 375572.0 336144.0 332481.0 380183.0 301083.0 True False 451911.4331907499 353527.5289770759 376983.39167629165 385553.4271992558 336704.08363569697 359509.66106109315 353547.8915547763 347929.28104156436 337362.7870355264 353124.79538212024 1.2797499328862805 1.0011404851775414 1.0675642056467707 1.0918333468541743 0.9534988424456169 1.0180810460281153 1.0011981491478055 0.9852870305101805 0.9553641982870742 1.0 18.429818600883756 -2.5555363248788265 1.4557746901835489 1.0056019189653589 199.99754287190532 0.7688884005610082 0.04391548756284863 486.8483273200619 1.8689982021106588 0.012602441721137394 322688.29223629663 0.0027826826174155144 2.5555363248788265 198.99194095293996 RGS(ph)MEQAPAVALPPTHK ddPTM_PC-9_AZD4547_30min_R2 2 RGSMEQAPAVALPPTHK 17 1 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 RGS(1)MEQAPAVALPPTHK;RGS(1)MEQAPAVALPPTHK 83.37 0.0014345 23003000.0 53444.0 56517.0 59340.0 60750.0 85497.0 64520.0 49301.0 90047.0 79198.0 66745.0 True False 70438.08029574256 74785.01499982772 58553.11282793279 46745.02607814374 73627.21733564425 60485.554200486265 53688.69349130779 76132.30522420818 83384.24459407851 64408.27786559695 1.0936184389641377 1.1611087499635415 0.9090929732683997 0.7257611541126476 1.143132835957589 0.9390959703456693 0.8335682193419595 1.1820267168620184 1.2946199985051516 1.0 15.97495849751949 -7.789246332812563 24.7960172198677 1.1787428120103878 0.97285872800342 0.25526294176638953 0.14493675310971318 271.7662448043565 242335.37157976118 0.08150284441350031 0.039166598464385166 1.6246270022540786e-08 7.789246332812563 -0.20588408400696778 RGS(ph)MEQAPAVALPPTHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RGSMEQAPAVALPPTHK 17 1 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 RGS(1)MEQAPAVALPPTHK;RGS(1)MEQAPAVALPPTHK 105.16 0.001065 12886000.0 118309.0 141216.0 93934.0 87441.0 107981.0 78672.0 67232.0 90370.0 58893.0 52961.0 True False 138336.3769907373 155234.99121596923 96173.74280667865 82541.96425754677 86822.89819809415 74546.3018258593 60863.29824247179 87997.88325492972 59754.19871039026 62562.410060954695 2.2111740397461648 2.481282147933934 1.5372448521880209 1.319353972731005 1.3877805876324523 1.1915509928921961 0.9728413304917849 1.406561594561226 0.9551134403577421 1.0 15.933008469496755 -5.431118067074488 2.4931826278603655 1.190809727521706 2.3673943013871126 0.8741388679982471 0.174347219809892 0.09090085297970417 1.0875499359332985 0.047852672502271675 0.12331214176412414 3.7057996240901362e-06 5.431118067074488 1.1765845738654066 up RGS(ph)MEQAPAVALPPTHK ddPTM_PC-9_Lapatinib_30min_R1 2 RGSMEQAPAVALPPTHK 17 1 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 RGS(1)MEQAPAVALPPTHK;RGS(1)MEQAPAVALPPTHK 75.018 0.0034398000000000002 19841400.0 91268.0 147721.0 158231.0 137102.0 134019.0 101111.0 113438.0 126622.0 137231.0 166335.0 True False 89966.50158349854 147378.96110045147 145221.85796932306 147184.93843886498 126136.26591149172 96786.71823125317 119311.26458360326 132505.3203763376 121774.59967350561 195085.78312254453 0.46116380262822865 0.7554572083188364 0.7444000051920796 0.7544626578268376 0.6465682116479924 0.4961238932026938 0.6115835950416594 0.6792156673615906 0.6242105279245901 1.0 17.573749119805896 -10.856965549293387 2.9246671149315984 1.0039749669041955 0.6472755243429559 0.5538874296452699 0.0964035761547457 11766852.499135502 14529850.927796947 404005.48440159275 0.025846977679942054 1.3900628945291434e-11 10.856965549293387 -0.35669944256123964 RGS(ph)MEQAPAVALPPTHKK ddPTM_PC-9_AZD4547_30min_R2 3 RGSMEQAPAVALPPTHKK 18 2 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 RGS(1)MEQAPAVALPPTHKK;RGS(1)MEQAPAVALPPTHKK;RGS(1)MEQAPAVALPPTHKK 78.661 0.0014 31605500.0 128562.0 101165.0 156044.0 242292.0 248255.0 161761.0 118003.0 201490.0 167191.0 197161.0 True False 169442.0417442791 133864.6078606009 153974.75460266182 186435.32277408408 213789.07844322507 151646.05909833926 128505.03839789845 170354.35027958418 176028.37493280842 190258.45340113767 0.8905887686736862 0.7035934827997526 0.8092925799098349 0.979905593897618 1.1236771592612278 0.797052937136051 0.6754235415073023 0.8953838698583972 0.9252065902253143 1.0 17.53760103018383 -14.522878695075441 0.29559214670160133 2.0993132144541624 0.8569652639961369 0.0967157519784041 0.12428354556209488 740.049142030884 6.898746914140285 502.8132641506867 0.14176679460039135 3.0000003468031583e-15 14.522878695075441 -1.2423479504580255 RGS(ph)MEQAPAVALPPTHKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGSMEQAPAVALPPTHKK 18 2 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 RGS(1)MEQAPAVALPPTHKK 73.593 0.017921 6383100.0 48293.0 34039.0 35592.0 37355.0 45210.0 46108.0 27911.0 53614.0 31630.0 25416.0 True False 56468.05106977208 37418.16696408601 36440.64826341166 35262.12045654402 36351.42504270054 43690.01531150497 25267.068021859093 52206.68930872861 32092.528911918966 30023.719607054703 1.8807813225281962 1.2462868509901028 1.2137286365693731 1.1744754120424987 1.2107568788431866 1.4551832978495802 0.8415702102387762 1.7388481504623947 1.0689058295221405 1.0 14.87381510155229 -4.761464123357026 7.0968795692325815 1.2330364201138055 1.8939078819961501 0.4205018335241375 0.23323465282633446 0.10150309773323145 30.801858145695242 0.05341595752461521 0.3231016976191662 1.7319520997119963e-05 4.761464123357026 0.6608714618823446 RGS(ph)MEQAPAVALPPTHKK ddPTM_PC-9_Lapatinib_30min_R1 2 RGSMEQAPAVALPPTHKK 18 2 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 RGS(1)MEQAPAVALPPTHKK;RGS(1)MEQAPAVALPPTHKK 108.18 8.8925e-05 16819600.0 373149.0 226272.0 242467.0 210743.0 184098.0 170124.0 130700.0 129812.0 200513.0 226051.0 True False 367827.8268328548 225748.08108610997 222532.2992096869 226241.74323803943 173269.71759059388 162848.19309841358 137467.0064799883 135843.53942200515 177929.11444450327 265123.6141559762 1.3873823650293788 0.8514823615571979 0.8393529935766785 0.8533443690343554 0.6535431336141061 0.6142349621207545 0.5185015560293109 0.5123781216338065 0.6711175653324675 1.0 18.01630564901197 -1.522878891443537 0.6603134744774328 0.639285580936794 68.81854927547366 0.669363218270668 0.14382453327433226 129.54649607775912 0.8038652894924139 0.05853443368734518 12940.587961613604 0.029999989903405577 1.522878891443537 68.17926369453686 RGS(ph)PAPANPGR ddPTM_PC-9_AZD4547_30min_R2 1 RGSPAPANPGR 11 1 E9PJN1;O75676-2;O75676 E9PJN1 RPS6KA4 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-4 1 RGS(1)PAPANPGR 76.24 0.030605 11136000.0 9814.8 11059.0 14937.0 21801.0 17272.0 17006.0 12666.0 20493.0 15784.0 15532.0 True False 12935.702239477841 14633.605479468037 14738.925620337583 16775.11627209239 14874.080936421733 15942.612131640884 13793.249462706735 17326.277732292016 16618.310016325348 14988.229407572857 0.863057395754967 0.976339838518508 0.9833666952609283 1.1192193431211228 0.9923841256997674 1.0636754814805425 0.9202721073736466 1.1559922964308147 1.1087573831722168 1.0 13.871542344170242 -4.519246704476512 1.0517859512532275 1.050502318677771 0.6786155813471874 0.4159718239998158 0.06709576086968042 2.8741527078174838 1.8043372494417262 0.021468534677391064 1.3651392619599099 3.025194453846654e-05 4.519246704476512 -0.37188673733058375 RGS(ph)PAPANPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGSPAPANPGR 11 1 E9PJN1;O75676-2;O75676 E9PJN1 RPS6KA4 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-4 1 RGS(1)PAPANPGR 65.565 0.020344 21751000.0 12611.0 9129.0 13389.0 17238.0 15607.0 8947.5 14107.0 15243.0 10822.0 11690.0 True False 14745.793221396392 10035.266788540817 13708.244538065257 16272.210746350045 12548.920385786932 8478.277348826467 12770.682834164527 14842.887401293514 10980.251276787454 13809.304462010921 1.0678157804371486 0.726703275762194 0.992681751334857 1.178351218999807 0.9087293585501517 0.6139539737247457 0.9247882736814429 1.0748468499717676 0.7951342739233445 1.0 13.753353036257817 -4.4388596634744 20.9418295158975 0.9156892569896349 9.815520082795162 0.07972340364774322 0.15772863197203396 768.4197417717088 191072.99204895517 0.039535699451604234 773.2439703746317 3.640326494660622e-05 4.4388596634744 8.899830825805527 RGS(ph)PAPANPGR ddPTM_PC-9_Lapatinib_30min_R1 1 RGSPAPANPGR 11 1 E9PJN1;O75676-2;O75676 E9PJN1 RPS6KA4 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-4 1 RGS(1)PAPANPGR 77.204 0.029031 10521000.0 12470.0 11863.0 13134.0 9927.1 10734.0 10876.0 10489.0 10333.0 13616.0 9549.0 True False 12292.17551328207 11835.53195236054 12054.173218706143 10657.17204983482 10102.647223855962 10410.858833194296 11032.069096928832 10813.10890247108 12082.42269716356 11199.531926757301 1.0975615403992274 1.0567880898739832 1.076310447395304 0.9515729871150503 0.9020597726695414 0.9295798164851201 0.985047336716959 0.9654965022812247 1.0788328276735302 1.0 13.45115081709507 -5.756719488815811 24.987824342155353 0.9674979610384973 1.0748768639899087 0.5203018070551306 0.04536653525878278 94.91072961590302 502464.21215628646 0.013105210098741113 0.021774653330692426 1.7509772812112478e-06 5.756719488815811 0.10737890295141139 RGS(ph)PSAAFTFPDTDDFGK ddPTM_PC-9_AZD4547_30min_R2 3 RGSPSAAFTFPDTDDFGK 18 1 Q9ULT0;Q9ULT0-4;H7C055;Q9ULT0-3 Q9ULT0 TTC7A Tetratricopeptide repeat protein 7A 1 RGS(0.65)PS(0.349)AAFT(0.001)FPDTDDFGK;RGS(0.819)PS(0.18)AAFT(0.001)FPDTDDFGK;RGS(0.5)PS(0.5)AAFTFPDTDDFGK 98.887 0.00031321 11848200.0 63477.5 69526.4 76150.0 106867.0 95477.0 85533.0 84402.0 98229.0 79562.1 85744.0 True False 83662.02458597775 91999.44913714506 75140.20124447384 82230.4642286912 82221.66660298393 80184.60798868866 91913.61449166045 83049.96512786386 83767.59017675355 82742.12865844223 1.0111176246302875 1.1118815847355927 0.9081250683633123 0.9938161558320167 0.993709829999579 0.9690904656283262 1.1108442093758297 1.0037204320750843 1.0123934630996068 1.0 16.336334452973055 RGS(ph)PSAAFTFPDTDDFGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RGSPSAAFTFPDTDDFGK 18 1 Q9ULT0;Q9ULT0-4;H7C055;Q9ULT0-3 Q9ULT0 TTC7A Tetratricopeptide repeat protein 7A 1 RGS(0.5)PS(0.5)AAFTFPDTDDFGK;RGS(0.923)PS(0.077)AAFTFPDTDDFGK 141.13 5.2448e-05 14293700.0 64286.0 64906.0 61794.0 76833.0 84075.0 67179.0 66511.0 68898.0 72028.0 56369.0 True False 75168.35009362367 71349.43873118966 63267.403315050055 72528.29610594704 67601.10728743741 63656.014978129475 60210.59658205974 67089.50050346534 73081.27323641145 66588.25348324145 1.12885300577138 1.0715018790686028 0.9501285888354593 1.089205562722869 1.0152106978515492 0.9559646281179315 0.9042224931941366 1.0075275592015647 1.097509987325379 1.0 16.022980080327585 -5.023115863916559 4.439974121730827 1.0011657101085025 1.1200152911505052 0.3468515283806638 0.05612234158908619 0.21163422001700788 10.261562115993703 0.015181351778841235 0.053434214986594994 9.481654717817141e-06 5.023115863916559 0.11884958104200272 RGS(ph)PSAAFTFPDTDDFGK ddPTM_PC-9_Lapatinib_30min_R1 2 RGSPSAAFTFPDTDDFGK 18 1 Q9ULT0;Q9ULT0-4;H7C055;Q9ULT0-3 Q9ULT0 TTC7A Tetratricopeptide repeat protein 7A 1 RGS(0.967)PS(0.033)AAFTFPDTDDFGK;RGS(0.75)PS(0.249)AAFTFPDTDDFGK 131.64 1.8623e-05 7930000.0 37900.8 37454.0 37941.8 31434.6 33020.3 30042.7 28469.8 25677.0 33416.7 23613.5 True False 37360.327641844524 37367.27756416689 34822.371663583435 33746.405346751584 31078.110874407583 28757.84375395424 29943.82694019874 26870.047158497044 29652.95935254887 27695.06201198906 1.3489887701161825 1.3492397145740558 1.2573494743759375 1.218498999285249 1.1221535037890153 1.0383744127926164 1.0811973241741146 0.9702107598410551 1.0706948169934498 1.0 14.7573411483915 -6.041427958727637 0.8185615327083842 1.016869261879381 1.3753417494560278 0.9445707640578059 0.031091981006582742 0.14178297038215443 0.19283256709220664 0.014537570740706588 0.032905539223287296 9.090170753665286e-07 6.041427958727637 0.35847248757664674 RGS(ph)PTTGFIEQK ddPTM_PC-9_AZD4547_30min_R2 3 RGSPTTGFIEQK 12 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RGS(0.993)PT(0.005)T(0.001)GFIEQK;RGS(0.773)PT(0.227)TGFIEQK;RGS(1)PTTGFIEQK 171.11 0.00092384 513710000.0 203760.0 198575.0 213249.0 239957.0 225845.0 224292.0 205985.0 227642.0 185628.0 212920.0 True False 268551.44152871217 262760.48540422897 210421.17892557854 184638.62094869374 194490.32011846744 210266.98578325313 224317.26595418007 192465.15959275953 195439.917112927 205465.73560780394 1.3070375979444435 1.2788530633924777 1.0241181007778037 0.8986346088436599 0.9465827455031892 1.0233676440563009 1.091750238990506 0.9367263063274934 0.9512044260556691 1.0 17.648538298074612 -5.279652239506935 3.857743275620732 0.9797872731927119 1.3021685150533926 0.8587264113902466 0.05043978541908355 0.07641652025868678 2.5833108827459967 0.014628931599631469 0.03733763558365557 5.2522786713829266e-06 5.279652239506935 0.32238124186068073 RGS(ph)PTTGFIEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 RGSPTTGFIEQK 12 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RGS(0.996)PT(0.004)TGFIEQK;RGS(0.992)PT(0.008)TGFIEQK;RGS(0.999)PT(0.001)TGFIEQK;RGS(0.995)PT(0.005)TGFIEQK;RGS(0.996)PT(0.004)TGFIEQK;RGS(0.942)PT(0.056)T(0.002)GFIEQK 141.65 0.00011614 486640000.0 399392.0 440171.0 401956.0 432722.0 478418.0 381357.0 436276.0 388432.0 354294.0 326529.0 True False 467001.17724842916 483868.2678912033 411540.15546661854 408477.98924365273 384675.42725234834 361357.9675793698 394948.7789152887 378236.07157772337 359474.87949160405 385726.1228978575 1.2107066374970246 1.2544347897830461 1.0669232158165154 1.0589845099804662 0.9972760578474292 0.936825239796008 1.0239098559053865 0.9805819443498839 0.9319433093900023 1.0 18.55721732872341 -5.500765521879926 1.2700931053294744 0.9776778641075573 1.2558561376845547 0.8761737828147509 0.03612056805666963 0.17301031099245856 0.494463528908877 0.01160733963249425 0.04481974602939677 3.156708488667273e-06 5.500765521879926 0.2781782735769974 RGS(ph)PTTGFIEQK ddPTM_PC-9_Lapatinib_30min_R1 4 RGSPTTGFIEQK 12 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RGS(0.975)PT(0.022)T(0.003)GFIEQK;RGS(0.982)PT(0.016)T(0.002)GFIEQK;RGS(0.98)PT(0.018)T(0.002)GFIEQK;RGS(0.766)PT(0.234)TGFIEQK 206.45 1.038e-07 652380000.0 306541.0 379485.0 377563.0 347853.0 380368.0 356942.0 367253.0 358849.0 363622.0 277709.0 True False 302169.6691272651 378606.3257979895 346521.2275753277 373435.27002359176 357995.50207226066 341676.42273244157 386267.5633572698 375522.43458268215 322667.0612505877 325710.6306260173 0.9277243071449454 1.1624008865486104 1.0638929006072424 1.146524659959202 1.0991213316685173 1.0490183328549576 1.1859224938862505 1.1529326932342563 0.9906556031972925 1.0 18.313231281985033 -4.748719695052418 24.975387004677835 1.101525594868983 0.9277238937557056 0.367728300043592 0.06501912697396324 619.8134138937477 1216944.0327003822 0.015334332054363355 0.2723156410106217 1.7835295323622353e-05 4.748719695052418 -0.17380170111327742 RGS(ph)PVPPVPER ddPTM_PC-9_AZD4547_30min_R2 4 RGSPVPPVPER 11 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RGS(1)PVPPVPER;RGS(1)PVPPVPER;RGS(1)PVPPVPER;RGS(1)PVPPVPER 86.214 0.0050609999999999995 665167100.0 50630.0 49759.7 62081.0 81475.0 75576.0 63022.0 59090.0 76486.0 52337.0 69212.0 True False 66729.28683057874 65843.54992103134 61257.765376995194 62692.19752620189 65083.576936719 59081.224377294595 64348.895527502034 64666.8461734293 55103.426971896864 66788.9089464933 0.99910730513711 0.9858455686674067 0.917184699424731 0.9386618005158098 0.9744668383317879 0.8845963395603067 0.9634667872633458 0.9682273178805173 0.8250385856136975 1.0 16.02732092631475 -5.167135117170931 5.183064534619375 0.9338018269627297 0.9953240779465609 0.19557001763143478 0.047644435780750505 0.341674524684931 14.388366690322469 0.0115855827418265 0.03251503377460438 6.80557591503041e-06 5.167135117170931 0.06152225098383113 RGS(ph)PVPPVPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 RGSPVPPVPER 11 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RGS(1)PVPPVPER;RGS(1)PVPPVPER;RGS(1)PVPPVPER;RGS(1)PVPPVPER;RGS(1)PVPPVPER;RGS(1)PVPPVPER 84.759 0.0054246 524564000.0 235657.0 262301.0 290070.0 294196.0 325666.0 292656.0 309064.0 293760.0 254979.0 216572.4 True False 275549.0756620893 288340.5097930827 296986.3688966004 277713.15191630134 261854.08511294215 277308.60416855616 279787.22049041046 286049.1112644485 258707.58550212413 255835.2617338254 1.0770566723080355 1.1270553864974102 1.1608500207668369 1.085515538531346 1.0235261681221208 1.083934256322617 1.0936225858556785 1.1180988473827271 1.0112272395479522 1.0 17.96485559879134 -11.854923588367459 0.11029569711421454 0.8259147530243346 1.159035724892744 0.4033820322652921 0.038407562718303354 84.79854752289634 1.198193664079812 4.2671175991809305 0.6320539039141817 1.3966140657047753e-12 11.854923588367459 0.3331209718684095 RGS(ph)PVPPVPER ddPTM_PC-9_Lapatinib_30min_R1 3 RGSPVPPVPER 11 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RGS(1)PVPPVPER;RGS(1)PVPPVPER;RGS(1)PVPPVPER 64.244 0.021854 320214000.0 88136.0 77667.0 97692.0 89940.0 102457.0 95956.0 82171.0 77118.0 90738.0 70581.0 True False 86879.16447783714 77487.16683334608 89660.14086202528 96554.48763104473 96430.6806982123 91852.18556436122 86425.41231420908 80701.1838131001 80518.1309265001 82780.83180672905 1.0495082325420042 0.9360520442009782 1.083102680960703 1.1663870188750152 1.1648914198319722 1.1095827809366707 1.0440268650113247 0.9748776625187293 0.9726663669493955 1.0 16.337009124824753 -7.597366741707529 3.582403607368053 0.9805130809382389 1.085129997235483 0.35685444907629726 0.061357112481102836 0.3054198360848378 7.818132933679562 0.03679135264988086 0.020091541051668133 2.527163022234959e-08 7.597366741707529 0.10461691629724423 RGS(ph)PVPPVPERR ddPTM_PC-9_Lapatinib_30min_R1 1 RGSPVPPVPERR 12 2 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RGS(1)PVPPVPERR 54.25899999999999 0.027364999999999997 7678500.0 13457.0 9656.2 13842.0 9567.1 10664.0 14334.0 12274.0 10054.0 12434.0 9618.4 True False 13265.100712288433 9633.841662175162 12703.964191665178 10270.696448910021 10036.764486230666 13720.968234186015 12909.48766285675 10521.145543931505 11033.55198417535 11280.927624287615 1.175887405192542 0.8539937479461964 1.1261453503445757 0.9104478630637975 0.8897109192174684 1.2162978693919675 1.1443640179964347 0.9326489712849222 0.9780713387807161 1.0 13.461598084159833 RGS(ph)QGDSK ddPTM_PC-9_AZD4547_30min_R2 1 RGSQGDSK 8 1 Q96HC4;Q96HC4-7;Q96HC4-4;Q96HC4-6;H0YBI4;Q96HC4-2 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 1 RGS(1)QGDSK 59.84 0.033076999999999995 1178600.0 6219.7 3603.5 10176.0 3769.1 15875.0 11903.0 4071.1 8630.9 6178.1 7239.1 True False 8197.43522220324 4768.260904716798 10041.059591119712 2900.1922270145133 13671.030272446447 11158.703528338325 4433.420013234278 7297.192723351348 6504.661753158874 6985.6613124105525 1.1734658832714777 0.6825783116976519 1.437381393409528 0.41516358971799905 1.957013038716726 1.5973725363000422 0.634645714265874 1.0445958366729484 0.9311447352311303 1.0 12.770180982540795 -7.2785466254503195 24.915768042356024 0.9063129418308811 1.1945937023661721 0.11292807151766449 0.42129521964521577 2117.981525665786 3084711.2773286817 0.1804316521359799 0.1219786611929366 5.2656668015177255e-08 7.2785466254503195 0.28828076053529106 RGS(ph)QGDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RGSQGDSK 8 1 Q96HC4;Q96HC4-7;Q96HC4-4;Q96HC4-6;H0YBI4;Q96HC4-2 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 1 RGS(1)QGDSK;RGS(1)QGDSK 73.666 0.013444999999999999 1532060.0 9011.2 26895.0 6355.4 12853.3 15434.7 13856.099999999999 6056.9 5872.1 8799.6 12290.4 True False 10536.618180687263 29564.957857137182 6506.936838988721 12133.171271960837 12410.38133392103 13129.461723730026 5483.146583841433 5717.963597004243 8928.277502792356 14518.552229247132 0.725734771230261 2.03635716497817 0.4481808334773709 0.8357011828988687 0.8547946887514539 0.904323069987734 0.377664831676248 0.39383841492718524 0.6149564613478914 1.0 13.825609976421486 -5.2861713453804215 24.992744416986852 0.6662392883583067 1.3810462614974246 0.3776175020666289 0.36039886475813654 639.519020405106 646261.2475793316 0.09024561249833205 0.1879927112451504 5.174026570189063e-06 5.2861713453804215 0.7148069731391179 RGS(ph)SDPTVQR ddPTM_PC-9_AZD4547_30min_R2 4 RGSSDPTVQR 10 1 H7BXG1;A0A2R8YDG4;H7BZJ9;H7BZI2;Q2KHT3-2;Q2KHT3 H7BXG1;Q2KHT3 CLEC16A Protein CLEC16A 1 RGS(0.982)S(0.017)DPTVQR;RGS(0.982)S(0.018)DPTVQR;RGS(0.989)S(0.011)DPTVQR;RGS(0.989)S(0.01)DPTVQR 117.95 0.00098201 87599400.0 41932.2 33184.4 43272.0 63136.9 62903.2 40241.8 36434.8 54340.1 45216.4 48582.5 True False 55265.76735605744 43910.60834368921 42698.185006577485 48581.66316038115 54170.17646826794 37725.47388445643 39677.42661643984 45943.08615627392 47606.446592889835 46881.64146236215 1.1788360141021574 0.9366269391173478 0.910765572081275 1.03626199179446 1.1554667195635038 0.8046960965465225 0.8463318556858542 0.9799803232819455 1.0154603189632252 1.0 15.51673546313537 -6.763859833233955 24.999995238721198 0.9228573959292449 1.0298625557673633 0.24237711735273837 0.09924466800791543 109.3847771473754 1129782.997576909 0.03601878952890694 0.03325669609982342 1.7224243907081033e-07 6.763859833233955 0.10700515983811842 RGS(ph)SDPTVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RGSSDPTVQR 10 1 H7BXG1;A0A2R8YDG4;H7BZJ9;H7BZI2;Q2KHT3-2;Q2KHT3 H7BXG1;Q2KHT3 CLEC16A Protein CLEC16A 1 RGS(0.892)S(0.108)DPTVQR;RGS(0.972)S(0.028)DPTVQR 94.68799999999999 0.0028451 37406700.0 23228.3 20222.2 15254.9 20190.9 27270.0 19183.4 14785.6 17432.5 18632.9 13235.7 True False 27160.392410162673 22229.726372136072 15618.63467053042 19059.66933278102 21926.63925933296 18177.38873355436 13385.000929525979 16974.915346260517 18905.37091251644 15635.227636256459 1.7371280445690833 1.4217718404423905 0.9989387448579539 1.2190209043444715 1.4023869539633291 1.162591882666479 0.856079696498154 1.0856839274215275 1.209152265150068 1.0 13.93251260343713 -4.960646244209142 2.9824637726304593 1.1265793196148952 1.7444224765890468 0.6543003345243974 0.14298601510210274 0.19047067033949988 3.1114212101059713 0.04025394833936913 0.23164500049232548 1.0948478145214517e-05 4.960646244209142 0.6178431569741516 RGS(ph)SDPTVQR ddPTM_PC-9_Lapatinib_30min_R1 5 RGSSDPTVQR 10 1 H7BXG1;A0A2R8YDG4;H7BZJ9;H7BZI2;Q2KHT3-2;Q2KHT3 H7BXG1;Q2KHT3 CLEC16A Protein CLEC16A 1 RGS(0.861)S(0.137)DPT(0.002)VQR;RGS(0.865)S(0.135)DPTVQR;RGS(0.495)S(0.495)DPT(0.01)VQR;RGS(0.887)S(0.11)DPT(0.003)VQR;RGS(0.905)S(0.092)DPT(0.003)VQR 102.33 0.0014932 91736600.0 61029.4 57612.6 59900.6 52898.8 50759.0 45808.4 44396.3 41206.8 48814.8 48041.7 True False 60159.10956457874 57479.20156440758 54975.80389100271 56789.15421722379 47773.45541603358 43849.28151659596 46694.923181235754 43121.418360819254 43316.76318136749 56345.64383345859 1.06767986789523 1.0201179302218901 0.9756886273852025 1.0078712452922907 0.847864221007716 0.7782195487232649 0.8287228613316129 0.7653017239145173 0.7687686258302292 1.0 15.782016457332979 -6.297264106964536 3.322155638001272 0.8130989987174198 1.018140775598478 0.6470504755850619 0.06709371103345318 0.14273572776932386 3.246152428047056 0.020494567535253343 0.024728183940603412 5.043544918128306e-07 6.297264106964536 0.20504177688105818 RGS(ph)SGSVDETLFALPAASEPVIR ddPTM_PC-9_AZD4547_30min_R2 3 RGSSGSVDETLFALPAASEPVIR 23 1 Q9NQC3-5;Q9NQC3 Q9NQC3-5 RTN4 Reticulon-4 1 RGS(0.607)S(0.197)GS(0.197)VDETLFALPAASEPVIR;RGS(0.454)S(0.272)GS(0.272)VDET(0.002)LFALPAASEPVIR;RGS(0.427)S(0.427)GS(0.146)VDETLFALPAASEPVIR 142.78 1.1042e-06 14373900.0 35794.2 43487.9 49124.9 46412.0 46895.1 50271.8 46805.5 58495.9 48387.9 44572.2 True False 47176.01103438866 57544.51322276498 48473.47172836055 35712.43045825198 40384.52483334827 47128.29639888416 50971.09882573189 49456.702757057545 50945.58560814429 43011.74084472179 1.0968170575727323 1.3378791951367062 1.1269823256714102 0.8302949324273736 0.9389186310580144 1.0957077177839347 1.1850508215825177 1.1498419218976266 1.1844576529014428 1.0 15.392442903234276 -5.517745145969502 24.972703580543712 1.0569081369363589 1.2211188105851853 0.23090492150967834 0.11850275934335917 318.72451516158065 1550451.7457752165 0.03504631793567319 0.06297157824595301 3.0356720640779112e-06 5.517745145969502 0.16421067364882647 RGS(ph)SGSVDETLFALPAASEPVIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RGSSGSVDETLFALPAASEPVIR 23 1 Q9NQC3-5;Q9NQC3 Q9NQC3-5 RTN4 Reticulon-4 1 RGS(0.45)S(0.45)GS(0.099)VDET(0.001)LFALPAASEPVIR;RGS(0.333)S(0.333)GS(0.333)VDET(0.002)LFALPAASEPVIR;RGS(0.331)S(0.331)GS(0.331)VDET(0.007)LFALPAASEPVIR 147.17 1.0625e-06 15921500.0 47438.3 68359.0 51795.0 53485.0 63290.0 38173.8 47289.3 35544.4 34268.6 38925.9 True False 55468.667240866576 75145.22975110753 53029.98923363138 50488.40885070956 50888.778831066455 36171.898726865766 42809.715159116524 34611.39716240485 34769.713445178175 45982.85753274515 1.2062901310856209 1.6342009562497368 1.1532556278362616 1.0979832824603373 1.1066902224340391 0.7866387751371728 0.9309929277150952 0.7527021811934481 0.7561451225691681 1.0 15.488808502417706 -6.033311882778191 0.9256925696040084 0.8262798224268125 1.4284942498487987 0.684265653701132 0.14238321101696028 0.3294700070485748 0.5760591709508635 0.061756924673023066 0.13225975847491384 9.261644718632497e-07 6.033311882778191 0.6022144274219862 RGS(ph)SGSVDETLFALPAASEPVIR ddPTM_PC-9_Lapatinib_30min_R1 4 RGSSGSVDETLFALPAASEPVIR 23 1 Q9NQC3-5;Q9NQC3 Q9NQC3-5 RTN4 Reticulon-4 1 RGS(0.494)S(0.253)GS(0.253)VDETLFALPAASEPVIR;RGS(0.577)S(0.212)GS(0.212)VDETLFALPAASEPVIR;RGS(0.736)S(0.206)GS(0.058)VDETLFALPAASEPVIR;RGS(0.331)S(0.331)GS(0.331)VDET(0.007)LFALPAASEPVIR 129.8 1.5274e-08 11049100.0 23040.899999999998 44629.700000000004 29934.399999999998 25542.899999999998 30064.6 33003.2 33757.9 29062.6 36844.7 21295.5 True False 22712.33254081644 44526.36267169058 27473.30918212558 27421.410074616528 28296.25933727782 31591.730070216785 35505.7188833267 30412.95449423749 32694.861894108555 24976.398800529896 0.9093517733362977 1.782737496598025 1.0999707924884154 1.0978928665262486 1.1329199042368547 1.264863294445256 1.4215707863606588 1.2176677165161316 1.3090302631384516 1.0 14.608277857810446 RGS(ph)SPGSLEIPK ddPTM_PC-9_AZD4547_30min_R2 4 RGSSPGSLEIPK 12 1 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 RGS(0.595)S(0.384)PGS(0.021)LEIPK;RGS(0.973)S(0.027)PGS(0.001)LEIPK;RGS(0.776)S(0.223)PGS(0.001)LEIPK;RGS(0.843)S(0.15)PGS(0.007)LEIPK 110.6 0.00053806 33808300.0 312319.0 298587.0 318598.0 374073.0 321121.0 355816.0 346165.0 359707.0 315264.0 356373.0 True False 411629.94536123815 395099.4085629732 314373.1823517645 287836.2492202379 276538.89210193895 333566.76927154674 376973.0143895368 304122.54839455226 331928.21141578746 343896.4897414987 1.1969588455836044 1.1488904956836368 0.9141505997577167 0.8369851330457011 0.8041340936914146 0.9699627045402044 1.096181629166675 0.8843432761502047 0.9651980212571881 1.0 18.39161486433938 -5.217317749435315 4.8714683738349365 0.9284343875204945 1.1812163716286652 0.5926925113499506 0.07936716123303071 0.1455365927141355 8.205895312505417 0.022360676733122652 0.061047255659696494 6.062925762728113e-06 5.217317749435315 0.25278198410817077 RGS(ph)SPGSLEIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RGSSPGSLEIPK 12 1 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 RGS(0.64)S(0.359)PGS(0.001)LEIPK;RGS(0.912)S(0.086)PGS(0.002)LEIPK;RGS(0.781)S(0.217)PGS(0.002)LEIPK;RGS(0.985)S(0.015)PGSLEIPK 110.57 0.00053941 26593300.0 208381.0 241670.0 217368.0 232727.0 264996.0 207708.0 223058.0 185868.0 184506.0 174551.0 True False 243655.78758764543 265661.400458611 222550.87749273027 219688.06070111398 213071.93608970274 196815.42683096338 201928.33143992876 180989.1619434243 187204.05119894125 206195.7145550438 1.1816724130927643 1.2883943831320164 1.0793186365341287 1.0654346584029921 1.033348033199901 0.9545078434616235 0.9793042104472259 0.8777542362312741 0.907894965726687 1.0 17.653654823367695 -5.787137795226344 0.7444873096265145 0.9279132415940344 1.2715184930747283 0.8190233900946848 0.05038438256220317 0.3708088995065031 0.36235911784128555 0.02484122471741497 0.08610794099466151 1.6325338868157176e-06 5.787137795226344 0.3436052514806939 RGS(ph)SPGSLEIPK ddPTM_PC-9_Lapatinib_30min_R1 3 RGSSPGSLEIPK 12 1 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 RGS(0.749)S(0.249)PGS(0.002)LEIPK;RGS(0.493)S(0.389)PGS(0.118)LEIPK;RGS(0.684)S(0.294)PGS(0.022)LEIPK 90.259 0.0032298 25085000.0 249846.0 318747.0 300282.0 278668.0 289948.0 288522.0 248802.0 301507.0 307316.0 220701.0 True False 246283.15022385446 318008.9609052566 275593.973082041 299162.17432919657 272893.8286997007 276182.586637632 261683.75016246442 315516.1159254178 272702.8358990538 258848.8737844031 0.9514553670764095 1.2285506838640075 1.0646906399584533 1.1557406835711044 1.0542592853890325 1.0669646060259326 1.0109518590388864 1.2189201803837602 1.0535214309110332 1.0 17.98175051568301 -6.310445339480761 24.99095661615839 1.0755344439794459 1.1067540795215083 0.026018620727427444 0.08635253844884168 1724.5289233243848 879433.7577000028 0.025703604512066235 0.029145275809120554 4.892768418856762e-07 6.310445339480761 0.03121963554206242 RGS(ph)SSDEEGGPK ddPTM_PC-9_AZD4547_30min_R2 2 RGSSSDEEGGPK 12 1 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 RGS(0.955)S(0.033)S(0.011)DEEGGPK;RGS(0.86)S(0.113)S(0.027)DEEGGPK 95.073 0.0062366999999999995 0.0 17875.6 13293.1 13155.5 13883.3 12778.8 12667.3 12927.2 10766.6 20402.0 22061.0 True False 23559.668964422115 17589.834614261363 12981.049474348993 10682.719679846798 11004.684198144165 11875.211728515498 14077.695756695288 9102.869361855035 21480.40806849149 21288.651104845794 1.1066773957819893 0.8262540697215666 0.6097638319317564 0.5018035021211448 0.5169272653277334 0.557818889981828 0.6612770197305209 0.4275925852241061 1.0090074736394194 1.0 14.37779691994552 -10.667301294166005 10.804537356234919 0.999999998411375 0.669200096012319 0.15187313551322013 0.213800241796917 1.0331698907948674e-09 1.4572097716185787e-10 0.21131880654002216 0.051252339207975894 2.1512887485954614e-11 10.667301294166005 -0.330799902399056 RGS(ph)SSDEEGGPK ddPTM_PC-9_Lapatinib_30min_R1 2 RGSSSDEEGGPK 12 1 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 RGS(0.801)S(0.156)S(0.043)DEEGGPK;RGS(0.965)S(0.033)S(0.002)DEEGGPK 95.06700000000001 0.006922199999999999 4046300.0 13152.5 18319.199999999997 12691.3 14485.400000000001 21491.0 12160.7 20015.2 21735.0 17404.5 18252.5 True False 12964.942938126898 18276.783017928286 11647.87030383473 15550.704637877852 20226.941632931677 11640.615208976273 21051.48912087425 22744.887447518526 15444.221932489945 21407.420305072515 0.6056284574865304 0.8537592459749846 0.544104340356916 0.7264165609993228 0.9448565658394102 0.5437654347459144 0.9833734668107614 1.0624768011925798 0.7214424583811445 1.0 14.385823334202724 -7.284530469269572 24.9030567242653 0.9470296111090509 0.7147603788029029 0.39166612028922343 0.14526448938821623 821.6210120415878 886089.8729677611 0.05878123890709069 0.03965942837976698 5.193612348386565e-08 7.284530469269572 -0.23226923230614804 RGS(ph)TTSIPSPQSDGGDPNQPDDR ddPTM_PC-9_AZD4547_30min_R2 2 RGSTTSIPSPQSDGGDPNQPDDR 23 1 Q8IYB1 Q8IYB1 MB21D2 Protein MB21D2 1 RGS(0.304)T(0.304)T(0.304)S(0.088)IPSPQSDGGDPNQPDDR;RGS(0.381)T(0.149)T(0.234)S(0.234)IPS(0.001)PQSDGGDPNQPDDR 120.72 6.6274e-09 33619000.0 27257.0 26216.3 26827.0 33002.0 36550.0 20458.9 14046.400000000001 30789.0 28423.0 23654.0 True False 35924.15901917997 34690.20628731149 26471.256451549598 25393.898775817295 31475.66339892396 19179.60174879616 15296.50238851759 26031.26751083486 29925.381753295467 22825.880659717262 1.5738345238340938 1.5197751536716038 1.1597036209106988 1.1125046675912937 1.3789462876878915 0.8402568135144948 0.6701385421467048 1.1404277407256584 1.3110285731979352 1.0 14.478382902361227 -5.0931445361655605 0.8235615344116037 1.0216794759054308 1.8012771045915912 0.4878955037906212 0.19476642845396216 1.5525000512741738 1.1051449729690381 0.08319272294341834 1.0138440062022147 8.069664216251226e-06 5.0931445361655605 0.7795976286861603 RGS(ph)TTSIPSPQSDGGDPNQPDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGSTTSIPSPQSDGGDPNQPDDR 23 1 Q8IYB1 Q8IYB1 MB21D2 Protein MB21D2 1 RGS(0.37)T(0.37)T(0.127)S(0.127)IPS(0.005)PQS(0.001)DGGDPNQPDDR 47.537 0.021261000000000002 13486000.0 6668.6 10246.0 11621.0 16980.0 11911.0 10826.0 10597.0 10403.0 10696.0 9008.9 True False 7797.4622691462955 11263.155166544999 11898.088712887928 16028.665649902747 9577.125053828931 10258.265501916207 9593.175444363893 10129.932272889608 10852.408765156035 10642.142255586836 0.7326966772176757 1.0583541260813487 1.1180163191900347 1.5061502905101773 0.8999245475036947 0.9639286203424781 0.901432739195695 0.9518696545868542 1.019757911942853 1.0 13.377500973097257 RGS(ph)TTSIPSPQSDGGDPNQPDDR ddPTM_PC-9_Lapatinib_30min_R1 2 RGSTTSIPSPQSDGGDPNQPDDR 23 1 Q8IYB1 Q8IYB1 MB21D2 Protein MB21D2 1 RGS(0.551)T(0.194)T(0.115)S(0.115)IPS(0.024)PQSDGGDPNQPDDR;RGS(0.331)T(0.331)T(0.163)S(0.163)IPS(0.011)PQSDGGDPNQPDDR 133.91 6.407899999999999e-07 15475700.0 14303.1 12561.5 17025.9 16916.2 16523.7 12940.1 12480.0 8698.4 18117.3 15388.6 True False 14099.135171132706 12532.41461852626 15626.096223874607 18160.273778788953 15551.808452844112 12386.68208784641 13126.153334891016 9102.559419070398 16076.738890373175 18048.499005979407 0.7811804830120062 0.6943743418427378 0.8657836986165849 1.006193023185613 0.8616676903542976 0.686299845972939 0.7272711891743665 0.5043388603149076 0.8907521276449086 1.0 14.139591240668944 -6.753844170089724 24.87719009187249 0.728599755910615 0.844108279994186 0.04874402122554078 0.1433405999906377 351.0791096754246 1149915.9920460794 0.0478887345517085 0.047000677136964396 1.7626083773431847e-07 6.753844170089724 0.11550852408357104 RGS(ph)VSSVSPKPPSSFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGSVSSVSPKPPSSFK 16 2 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 RGS(0.968)VS(0.023)S(0.005)VS(0.003)PKPPSSFK 51.54600000000001 0.027849000000000002 4887100.0 34409.0 29885.0 26563.0 29660.0 37973.0 32023.0 32879.0 36932.0 31607.0 26988.0 True False 40233.764091271754 32851.7852969156 27196.36266073849 27998.2463590174 30532.46324146132 30343.657506730353 29764.46309665384 35962.57413268859 32069.192580430707 31880.710763109535 1.262009633042055 1.0304596262304708 0.8530663843357127 0.8782190135928623 0.9577096153324057 0.9517873592028642 0.9336198091008532 1.1280355196566805 1.005912095835055 1.0 14.96039617333777 -10.289612584310843 13.812191553941963 1.0000001695613274 0.9922163087187861 0.0 0.1146744383875475 0.0 0.0 0.11656958452944029 0.02827227704407346 5.133190900016108e-11 10.289612584310843 -0.007783860842541346 RGS(ph)VSSVSPKPPSSFK ddPTM_PC-9_Lapatinib_30min_R1 1 RGSVSSVSPKPPSSFK 16 2 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 RGS(0.859)VS(0.121)S(0.019)VS(0.001)PKPPSSFK 57.328 0.018539 7093600.0 44070.0 25394.0 33333.0 41362.0 38787.0 34272.0 34957.0 33183.0 40428.0 36784.0 True False 43441.55371855179 25335.201753202702 30592.489409100937 44403.89945958718 36505.624918176014 32806.26645193408 36766.902414085365 34724.80332049723 35874.572914286735 43142.065388400915 1.0069419098843468 0.5872505529142856 0.709110450176221 1.0292483463604762 0.846172397856289 0.7604241047938866 0.8522286098979962 0.8048943185235927 0.8315450962144223 1.0 15.396807625456173 -14.522878745276442 0.32240431491973953 2.729970146269104 0.8125258606446987 0.15056129419220465 0.1229791183614963 647.3051480626646 5.703017063421562 764.8694887999718 0.10950081866743541 3.0000000000269106e-15 14.522878745276442 -1.9174442856244056 RGSDAS(ph)DFDLLETQSACSDTSESSAAGGQGNSR ddPTM_PC-9_AZD4547_30min_R2 1 RGSDASDFDLLETQSACSDTSESSAAGGQGNSR 33 1 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y6T5;H0Y4F5;H0Y314 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 RGS(0.457)DAS(0.542)DFDLLETQSACSDTSESSAAGGQGNSR 63.394 0.0021550000000000002 0.0 1325.3 2472.6 3627.6 3555.6 2966.5 4653.2 5350.5 3864.4 3501.6 3771.8 True False 1746.7178320475186 3271.8195956716377 3579.4956537682688 2735.9113534723942 2554.652680517317 4362.234668408287 5826.684134708069 3267.2457750777967 3686.6874273419203 3639.7504300465694 0.4799004397741551 0.8989131696125044 0.9834453549944275 0.7516755354672461 0.7018757823141822 1.1984982905414405 1.6008471588074016 0.8976565393347569 1.0128956636443753 1.0 11.82962381594377 -6.765663893733939 24.98695417745954 1.1642623472031473 0.78230358884673 0.43219188601556 0.21579187052437168 110.1002746752836 651210.87595039 0.07790512330059862 0.07113705562952252 1.71528427523919e-07 6.765663893733939 -0.38195875835641724 RGSFDAT(ph)GSGFSMTFSSSSYSSSGYGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGSFDATGSGFSMTFSSSSYSSSGYGR 27 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 RGS(0.103)FDAT(0.289)GS(0.257)GFS(0.289)MT(0.051)FS(0.01)S(0.002)S(0.001)SYSSSGYGR 44.301 0.01873 2436400.0 892.78 958.74 2015.3 2323.1 2665.2 3181.7 2053.9 901.99 490.46 561.86 True False 1043.9100207912343 1053.9173711080762 2063.35239506781 2192.9442385918182 2142.973192298283 3014.8460509372626 1859.3397230517135 878.3137182374026 497.6320496408402 663.7207703186875 1.5728150563828185 1.5878927076548088 3.1087657450844652 3.3040162921809264 3.228727031202184 4.542340974939921 2.8013884847372577 1.3233181143565502 0.749761152422427 1.0 9.374432612064673 -5.243493079664253 22.115883248799342 2.656240802215239 1.5803523420837016 0.0862417844429113 1.126284577306339 424.8881136836702 523592.38648525 0.3107699623959651 0.8163629088644875 5.708301720852084e-06 5.243493079664253 -1.0758884601315375 RGSFDATGS(ph)GFSMTFSSSSYSSSGYGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGSFDATGSGFSMTFSSSSYSSSGYGR 27 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 RGS(0.062)FDAT(0.198)GS(0.465)GFS(0.198)MT(0.064)FS(0.008)S(0.004)S(0.001)SYSSSGYGR 55.17100000000001 0.0015275 18822000.0 13465.0 16017.0 12423.0 23387.0 28878.0 21725.0 27950.0 25804.0 19983.0 18578.0 True False 15744.358554127533 17607.061907334682 12719.211434489867 22076.702211677028 23219.563202457553 20585.702755323273 25302.373659523524 25126.67234159797 20275.213570878186 21946.04433663293 0.7174121364480534 0.8022886328514565 0.5795673807720608 1.0059535956931427 1.0580295403713749 0.9380142698864898 1.1529355026995967 1.1449294440572986 0.9238664271280201 1.0 14.421673304266596 -5.8421973160707745 6.895287840307534 1.0425122301977034 0.7110960327148509 0.7524817476584958 0.08721532513877268 0.10184875224755453 7.14852119602151 0.024573933898375575 0.03680211659432529 1.4381450272415382e-06 5.8421973160707745 -0.33141619748285256 RGSGDT(ph)SSLIDPDTSLSELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGSGDTSSLIDPDTSLSELR 20 1 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 RGS(0.075)GDT(0.545)S(0.188)S(0.188)LIDPDT(0.001)S(0.002)LS(0.001)ELR 64.374 0.023575 35447000.0 5658.9 6285.9 6650.4 6102.2 5943.5 5427.8 5917.9 4773.6 3310.2 1754.0 True False 6616.8400016303185 6909.9226099341395 6808.970757782448 5760.3135175993275 4778.9138407717455 5143.156612904197 5357.313670114289 4648.298058047282 3358.605412716857 2071.9863153436386 3.193476690763238 3.334926760261025 3.2862045021051123 2.7800924528036663 2.3064408318638745 2.4822348365998765 2.5855931723302814 2.243401910343391 1.6209592639900388 1.0 11.01679875928353 -7.36025912440719 0.1616848022452508 0.2533599873068743 4.447374370390769 0.9127587855482527 0.2089696026776226 1.6163069452375118 0.19122130435107126 1.7082273812904607 2.5252456372515346 4.3625546013498844e-08 7.36025912440719 4.1940143830838945 RGSGDT(ph)SSLIDPDTSLSELR ddPTM_PC-9_Lapatinib_30min_R1 1 RGSGDTSSLIDPDTSLSELR 20 1 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 RGS(0.002)GDT(0.677)S(0.121)S(0.121)LIDPDT(0.038)S(0.038)LS(0.004)ELR 66.708 0.020003 3643200.0 4598.0 5653.9 6569.2 6338.2 5656.3 5586.3 4689.5 6995.7 6962.3 5890.0 True False 4532.431676830069 5640.808741924579 6029.105733845317 6804.332371615376 5323.607554713667 5347.38697130133 4932.299364100278 7320.745761058447 6178.132457730741 6908.078652068332 0.6561059746291429 0.816552478052009 0.872761593708861 0.9849818906705856 0.7706350525004138 0.7740773144932681 0.7139900415904369 1.0597368863000074 0.8943344117659924 1.0 12.754068793455817 -7.764656763197165 24.999967989993475 0.9827767401637193 0.8071662056651705 0.46263080678206336 0.09164130117287865 84.89023426017957 659597.1397485519 0.0499496938137493 0.025569061762814187 1.7192666417008094e-08 7.764656763197165 -0.1756105344985488 RGSGDTS(ph)SLIDPDTSLSELR ddPTM_PC-9_AZD4547_30min_R2 1 RGSGDTSSLIDPDTSLSELR 20 1 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 RGS(0.001)GDT(0.018)S(0.668)S(0.197)LIDPDT(0.108)S(0.005)LS(0.002)ELR 120.82 1.613e-05 53685000.0 7383.7 10509.0 8914.9 8967.0 10756.0 12767.0 10938.0 14051.0 10906.0 12306.0 True False 9731.563009499181 13905.828735304234 8796.682601107814 6899.79668876897 9262.715062074583 11968.677471754627 11911.460810286295 11879.740809858738 11482.468894959717 11875.170685654883 0.8194882639670044 1.1710003252502612 0.7407626242992987 0.581027159222551 0.7800068990388386 1.0078741424923432 1.0030559665702532 1.0003848470329253 0.966930850840776 1.0 13.535660629462773 -6.7671966644344055 24.960512874578757 0.9961361699345727 0.820535879308739 0.2930835773527827 0.13757501053308013 208.59635662374964 904356.3058718002 0.053063521112111676 0.04805812326834993 1.7092411328798788e-07 6.7671966644344055 -0.1756002906258337 RGSGDTS(ph)SLIDPDTSLSELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGSGDTSSLIDPDTSLSELR 20 1 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 RGS(0.034)GDT(0.201)S(0.382)S(0.382)LIDPDTSLSELR 84.581 0.0011612999999999999 35721000.0 9537.3 16319.0 13263.0 16153.0 18705.0 12629.0 15585.0 13381.0 11911.0 8817.1 True False 11151.776519738618 17939.042471486202 13579.240220207595 15247.999778732583 15039.889524966005 11966.713007916105 14108.675974371168 13029.762928341432 12085.175841601864 10415.5704338748 1.0706832228285297 1.7223293323563575 1.3037442650326208 1.4639620437053704 1.4439813566092765 1.1489253597668052 1.354575446821923 1.2509888931252804 1.1602989887425625 1.0 13.346454233770656 -8.219159778308422 0.49928098851387476 0.9941038711153092 1.4190098912447493 0.3352367996168458 0.16622514358762133 0.9719873177819426 0.6200136187591276 0.1730144908438696 0.09616114896677146 6.0372647564053175e-09 8.219159778308422 0.4249060201294401 RGSGDTSS(ph)LIDPDTSLSELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGSGDTSSLIDPDTSLSELR 20 1 C9JSU1;Q9Y608-2;Q9Y608-4;Q9Y608-5;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 RGS(0.247)GDT(0.198)S(0.247)S(0.309)LIDPDTSLSELR 49.266000000000005 0.026258 1238200.0 2257.3 2743.1 3250.2 2390.5 2876.6 2783.4 2151.6 2232.6 2599.0 1041.3 True False 2639.4163062927637 3015.41683948366 3327.69709445214 2256.5680351055685 2312.9508798458805 2637.4336041043407 1947.7848717649667 2173.996615635235 2637.0054581750665 1230.0794470737353 2.1457283206964664 2.4514000674160563 2.705270055823204 1.8344896668859647 1.8803264174100407 2.1441164718088683 1.5834626587726488 1.7673627673456427 2.143768408169326 1.0 10.264535782501238 -9.455690501919067 0.11681904859539778 3.3727351903525013e-12 3.016582360616043 0.6203372148755701 0.27702508062699965 16.176469063456583 0.6440016294468575 10.982346463093103 5.091079016506741 3.5019464281885327e-10 9.455690501919067 3.01658236061267 RGSGS(ph)PEDTPR ddPTM_PC-9_AZD4547_30min_R2 1 RGSGSPEDTPR 11 1 Q96HP0 Q96HP0 DOCK6 Dedicator of cytokinesis protein 6 1 RGS(0.014)GS(0.73)PEDT(0.256)PR 79.639 0.025056000000000002 2645200.0 7394.7 8424.2 10300.0 15139.0 11402.0 11472.0 8928.8 11850.0 10268.0 10805.0 True False 9746.060780684971 11147.157905790275 10163.41527009956 11648.937445218415 9819.029112846263 10754.654026472075 9723.445902622438 10018.85478591033 10810.745517462532 10426.720238786042 0.9347196968449287 1.0690953291644192 0.9747470956680107 1.1172197180361552 0.9417179024637827 1.031451288629205 0.9325507618831552 0.9608826703378397 1.0368308796900454 1.0 13.347997804008635 RGSLEMS(ph)SDGEPLSR ddPTM_PC-9_AZD4547_30min_R2 1 RGSLEMSSDGEPLSR 15 1 Q6ZN18-2;Q6ZN18 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 RGS(0.101)LEMS(0.449)S(0.449)DGEPLSR 123.63 4.6308000000000005e-05 1914200.0 4115.5 5357.8 5072.9 9554.7 6735.5 5953.1 4534.5 6187.2 4501.2 6453.9 True False 5424.14339228217 7089.604072510514 5005.6300314260225 7352.011533643463 5800.392088192949 5580.851715916229 4938.061715509529 5231.110407711762 4739.124242618073 6227.950925414275 0.8709354741618108 1.1383525909910608 0.8037362675739219 1.1804864267061348 0.9313483933412842 0.8960975741062055 0.7928870626386728 0.8399408521934998 0.7609443779139659 1.0 12.604541861073193 -6.7716667663631585 2.769324831162089 0.8376010899739952 0.9986513257490235 0.22722709000909724 0.12001865918396872 0.3447348301388079 5.424519220549789 0.041854257446623834 0.03860903655402227 1.6917385026981865e-07 6.7716667663631585 0.1610502357750283 RGSLGEEGS(ph)EPPPPPPLPLAR ddPTM_PC-9_AZD4547_30min_R2 1 RGSLGEEGSEPPPPPPLPLAR 21 1 Q14934-2;Q14934-9;Q14934-4;Q14934-6;Q14934;Q14934-12;Q14934-3;Q14934-5;Q14934-7;Q14934-8;Q14934-11;Q14934-13;Q14934-14;Q14934-15;Q14934-16;Q14934-17;Q14934-18;Q14934-10 Q14934-2 NFATC4 Nuclear factor of activated T-cells, cytoplasmic 4 1 RGS(0.381)LGEEGS(0.619)EPPPPPPLPLAR 89.46799999999999 0.00019653 2889100.0 5973.8 6630.6 9938.8 9416.6 11917.0 9610.9 5881.7 7435.3 7139.2 8368.4 True False 7873.344137240977 8773.811781549932 9807.005018103446 7245.748355019733 10262.530252393346 9009.92890368031 6405.159905637309 6286.3452311965475 7516.56353703433 8075.424863142717 0.9749758397450935 1.086482993804418 1.2144258889540145 0.897259088879678 1.2708347147445902 1.1157219658872426 0.7931669248600512 0.7784538074136804 0.9307948082510058 1.0 12.97932244933857 -7.254692038747276 24.868368561350845 0.8571417006052109 1.0976411069733012 0.4532431822797287 0.1163630929645106 409.7794222795704 1510309.1392715343 0.044191580988430935 0.033432160290028996 5.562985926613287e-08 7.254692038747276 0.2404994063680903 RGSLPAGAS(ph)WQNTDLFEMIEK ddPTM_PC-9_Lapatinib_30min_R1 1 RGSLPAGASWQNTDLFEMIEK 21 1 J3KPC5;P47736-3 J3KPC5 RAP1GAP Rap1 GTPase-activating protein 1 1 RGS(0.182)LPAGAS(0.796)WQNT(0.022)DLFEMIEK 48.336999999999996 0.020666999999999998 4402000.0 24188.0 20663.0 24484.0 18891.0 19901.0 17226.0 16511.0 15640.0 21112.0 18848.0 True False 23843.074684464067 20615.156093030928 22471.02003097315 20280.307158528623 18730.46230687138 16489.284135767273 17365.858791056537 16366.691496627092 18734.14424078416 22105.851686618647 1.0785865671439845 0.9325655661351386 1.0165190805371933 0.9174180414322113 0.8473078790359164 0.7459239467235159 0.7855774587309217 0.7403782368871296 0.8474744382784634 1.0 14.432140698568453 -6.108579450934037 2.0383570341371096 0.8051592107879966 1.0035502252917596 0.5172944500292064 0.07733557170355801 0.2349587454543274 1.9286406532858038 0.024145846533953463 0.0351131322604772 7.787903276427959e-07 6.108579450934037 0.19839101450376306 RGSLPDTQPSQGPS(ph)TPKGER ddPTM_PC-9_AZD4547_30min_R2 1 RGSLPDTQPSQGPSTPKGER 20 2 A0A494BYR6;Q86Y91-6;Q86Y91 A0A494BYR6 KIF18B Kinesin-like protein KIF18B 1 RGSLPDTQPS(0.011)QGPS(0.494)T(0.494)PKGER 40.759 0.039915 4662900.0 14638.0 10326.0 13788.0 22685.0 19894.0 15320.0 14930.0 17503.0 16373.0 15994.0 True False 19292.579510685573 13663.67756406429 13605.16211108084 17455.323729756237 17132.061495436195 14362.037978168779 16258.741076757575 14798.313528927294 17238.44335385802 15434.054928194726 1.250000703019538 0.8852940868509976 0.8815027660830149 1.1309616177320378 1.1100168798893915 0.9305421060755977 1.0534328893087146 0.958809178649088 1.1169095506046867 1.0 13.913829524818658 -4.741884104840623 24.954345334049993 1.0083647797638347 1.2500015458836737 0.40115894998156054 0.08888122361081062 1483.955716350223 1893565.0499149316 0.022727882365295767 0.8654645510977484 1.8118235285603417e-05 4.741884104840623 0.24163676611983909 RGSLT(ph)LTISGESPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGSLTLTISGESPK 14 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RGS(0.215)LT(0.618)LT(0.167)ISGESPK 132.24 4.7248e-05 25418000.0 33410.0 34246.0 29833.0 39435.0 40714.0 35069.0 39762.0 44094.0 31491.0 31907.0 True False 39065.65312242117 37645.71655607066 30544.331862282528 37225.584799994984 32736.383967894457 33229.9199045538 35995.4555080492 42936.57922145483 31951.496299881135 37691.48652432696 1.0364582754571723 0.9987856682641914 0.8103774798738306 0.9876390727112535 0.8685352313383988 0.8816293271719712 0.9550022784274347 1.1391585522566896 0.8477112272889237 1.0 15.201951074498213 -7.533233193107151 24.976355993500473 1.005477002965443 0.9271768285810312 0.08933487868308032 0.09092427472640693 448.92741741952125 1082859.386488052 0.04154275953971473 0.024017332877066637 2.9293199334264175e-08 7.533233193107151 -0.07830017438441172 RGSPS(ph)AAFTFPDTDDFGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGSPSAAFTFPDTDDFGK 18 1 Q9ULT0;Q9ULT0-4;H7C055;Q9ULT0-3 Q9ULT0 TTC7A Tetratricopeptide repeat protein 7A 1 RGS(0.237)PS(0.763)AAFTFPDTDDFGK 142.4 8.7496e-09 0.0 13281.0 12868.0 10299.0 13399.0 17461.0 11783.0 12183.0 13579.0 14194.0 12736.0 True False 15529.210988293178 14145.449998350678 10544.567219174996 12648.297470144109 14039.64239483729 11165.078737213991 11028.938042718253 13222.565638139773 14401.560397590192 15044.935981879482 1.0321885720881079 0.940213372485455 0.7008715246030393 0.840701315404602 0.93318060055204 0.7421154035259111 0.7330664654207766 0.8788715122527194 0.9572364026630497 1.0 13.876990347382447 -8.273142827615551 3.1030635848870127 0.9917956438279197 0.8415564677255647 0.22075887263178606 0.09831522517806755 0.3952476344421959 7.2711748759131405 0.09480534952782885 0.0270708526076947 5.331595250189022e-09 8.273142827615551 -0.15023917610235504 RGSPS(ph)AAFTFPDTDDFGK ddPTM_PC-9_Lapatinib_30min_R1 1 RGSPSAAFTFPDTDDFGK 18 1 Q9ULT0;Q9ULT0-4;H7C055;Q9ULT0-3 Q9ULT0 TTC7A Tetratricopeptide repeat protein 7A 1 RGS(0.173)PS(0.827)AAFTFPDTDDFGK 136.64 4.1352e-05 5916500.0 55389.0 62882.0 54333.0 54187.0 55945.0 54276.0 44077.0 43878.0 57511.0 39507.0 True False 54599.142702901445 62736.40059245857 49865.950471445154 58172.09274253298 52654.42509210192 51954.742003535604 46359.09138958264 45916.73206451427 51033.50556232178 46335.73231023148 1.178337753191079 1.3539529314529821 1.0761878141382943 1.2554477903371324 1.1363676037224344 1.1212673117084497 1.0005041266898462 0.9909572974284322 1.1013855402270825 1.0 15.49983755240138 -6.790511954778797 1.3770738031250338 1.0211395552961235 1.2196556554767757 0.5727219952857407 0.07288567764798301 0.2946680569643827 1.1670508124126073 0.03349440019384115 0.029496198148309376 1.6198994024884124e-07 6.790511954778797 0.19851610018065213 RGSS(ph)DPTVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RGSSDPTVQR 10 1 H7BXG1;A0A2R8YDG4;H7BZJ9;H7BZI2;Q2KHT3-2;Q2KHT3 H7BXG1;Q2KHT3 CLEC16A Protein CLEC16A 1 RGS(0.336)S(0.642)DPT(0.022)VQR;RGS(0.316)S(0.659)DPT(0.025)VQR 98.368 0.007031100000000001 24606900.0 74456.0 70348.0 62386.0 65530.0 70724.0 54308.0 40311.0 57035.0 38906.0 37841.0 True False 87059.93022696783 77331.68452626464 63873.51884022255 61858.566551126474 56866.13989648206 51459.992876229946 36492.45025363339 55537.89168357775 39474.926647079345 44701.27375080884 1.94759394804477 1.72996601746422 1.4288970644615422 1.3838211165069358 1.2721369018137454 1.1511974616897536 0.8163626490167538 1.2424230234059679 0.8830828147568183 1.0 15.448028320752082 -4.57296924713416 0.4235509052744953 0.958315495388149 2.8758034465032596 0.8828885032780911 0.11603879749343754 1.9801699494913119 0.24380998576998195 0.08691513462577717 1.9927437125383458 2.6731956938635563e-05 4.57296924713416 1.9174879511151106 RGSS(ph)GSVDETLFALPAASEPVIR ddPTM_PC-9_Lapatinib_30min_R1 1 RGSSGSVDETLFALPAASEPVIR 23 1 Q9NQC3-5;Q9NQC3 Q9NQC3-5 RTN4 Reticulon-4 1 RGS(0.247)S(0.376)GS(0.376)VDET(0.001)LFALPAASEPVIR 103.57 1.3965999999999999e-06 4330600.0 13320.0 24515.0 18047.0 13864.0 18382.0 14921.0 19881.0 17005.0 20975.0 13087.0 True False 13130.054357411165 24458.23702369712 16563.245323434574 14883.604808948226 17300.8069004025 14282.863612549838 20910.340901519903 17795.114379804592 18612.5746234581 15349.070512668639 0.8554299328141096 1.593466979222622 1.079104126192123 0.9696746650986956 1.1271566500475034 0.9305360608488451 1.3623196847171408 1.1593610417723383 1.212619005697828 1.0 13.905863673101589 -11.900952477795633 2.181338686319679 9.026090532504729e-06 1.1497242175269422 0.041454784098407305 0.20462649098933614 8810835.100014022 739318.6730801997 43841463.08246717 0.049504691914188714 1.25616741093621e-12 11.900952477795633 1.1497151914364097 RGSS(ph)PGSLEIPK ddPTM_PC-9_AZD4547_30min_R2 1 RGSSPGSLEIPK 12 1 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 RGS(0.46)S(0.54)PGS(0.001)LEIPK 100.41 0.0049993 0.0 33536.0 38296.0 39225.0 40307.0 49294.0 41540.0 39346.0 44856.0 34427.0 42242.0 True False 44199.75040786658 50674.433080903145 38704.85087084027 31014.84388694224 42450.378976376414 38942.49723323313 42847.717776698155 37924.535888337035 36246.74093588651 40763.12043746413 1.0843073330383204 1.2431441100944234 0.949506574949739 0.7608554878550821 1.0413917904420678 0.9553365104365827 1.0511392974056553 0.93036390446404 0.8892042745229397 1.0 15.314976874314743 -5.2759835164048585 24.062096700877646 0.9454457131803733 1.1637257070888425 0.5047974709528233 0.08575893574416783 334.9998123897138 554230.6504421661 0.022596790256562714 0.04742385844203841 5.2968354758586465e-06 5.2759835164048585 0.2182799939084692 RGSSAAASPGS(ph)PPPGR ddPTM_PC-9_AZD4547_30min_R2 4 RGSSAAASPGSPPPGR 16 1 Q86UX6 Q86UX6 STK32C Serine/threonine-protein kinase 32C 1 RGSSAAASPGS(1)PPPGR;RGSSAAAS(0.001)PGS(0.999)PPPGR;RGSSAAAS(0.004)PGS(0.996)PPPGR;RGSSAAAS(0.018)PGS(0.982)PPPGR 105.52 0.00051456 17694200.0 13440.9 10634.900000000001 24271.1 32428.8 22784.9 22096.0 14327.3 21268.6 16995.6 23144.799999999996 True False 17714.826611912387 14072.423448195543 23949.249355544976 24952.841179965577 19621.60993100253 20714.33362699852 15602.401944342198 17982.02657380696 17893.95271879493 22334.507596728847 0.7931594880787493 0.6300753838986186 1.0722980684406325 1.1172326531891044 0.8785333567808922 0.9274587110231335 0.6985782819150826 0.8051230364461065 0.8011796383375702 1.0 14.446986827806548 -7.201857353499057 24.999256389119676 0.8099795402170488 0.9070187924917795 0.05823691225379901 0.14526423669380722 696.1323388149385 292080.98173610587 0.059687963091234184 0.046234088166631535 6.282646820475394e-08 7.201857353499057 0.09703925227473076 RGSSAAASPGS(ph)PPPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RGSSAAASPGSPPPGR 16 1 Q86UX6 Q86UX6 STK32C Serine/threonine-protein kinase 32C 1 RGSSAAAS(0.001)PGS(0.998)PPPGR;RGSSAAASPGS(1)PPPGR;RGSSAAASPGS(1)PPPGR;RGSSAAASPGS(1)PPPGR 85.054 0.0022105000000000002 12346700.0 5509.38 6374.400000000001 9516.7 10028.9 12971.5 14466.5 10883.6 10856.5 12668.9 11814.800000000001 True False 6442.009218784934 7007.20830505801 9743.614220285732 9467.013247132492 10429.827691691882 13707.851273182232 9852.626617559588 10571.528378412586 12854.158695295919 13956.729714094665 0.4615701063752247 0.5020666337029905 0.6981301794822193 0.6783117134934494 0.7472973902445769 0.9821678540739315 0.705940920214969 0.7574502476562671 0.9210007615404863 1.0 13.768673314079157 -4.488107464766443 0.35674162347091026 0.9069989122875992 1.4209963330998287e-24 0.742146617486236 0.08794163127819575 4.404322851351198 0.3819608548120428 0.08437010798622918 1.7953418893885547 3.250068655356882e-05 4.488107464766443 -0.9069989122875992 down RGSSAAASPGS(ph)PPPGR ddPTM_PC-9_Lapatinib_30min_R1 5 RGSSAAASPGSPPPGR 16 1 Q86UX6 Q86UX6 STK32C Serine/threonine-protein kinase 32C 1 RGSSAAASPGS(1)PPPGR;RGS(0.001)S(0.001)AAAS(0.208)PGS(0.79)PPPGR;RGSSAAAS(0.002)PGS(0.998)PPPGR;RGSSAAAS(0.001)PGS(0.999)PPPGR;RGSSAAASPGS(1)PPPGR 144.57 1.3473e-05 16945500.0 27502.6 19907.5 26252.800000000003 19783.5 25312.7 24400.5 21149.3 24722.5 29054.4 18168.8 True False 27110.407880640865 19861.405406863156 24094.396122738606 21238.444585821355 23823.85675268295 23356.947495343626 22244.307269680332 25871.197603923494 25781.987515604364 21309.252871595763 1.2722364338159302 0.932055456216275 1.1307011216172347 0.9966771108212437 1.118005257914933 1.0960941538441895 1.0438802056420735 1.2140828099331717 1.209896361498931 1.0 14.379192390908482 -7.752424719320198 24.99959938035234 1.1589921961213592 1.0785570121554802 0.05259208815882055 0.101177414046009 393.15376678919546 1090307.4290225995 0.04488236980580919 0.02544327588884741 1.768378722239069e-08 7.752424719320198 -0.08043518396587901 RGSSGS(ph)VDETLFALPAASEPVIR ddPTM_PC-9_AZD4547_30min_R2 1 RGSSGSVDETLFALPAASEPVIR 23 1 Q9NQC3-5;Q9NQC3 Q9NQC3-5 RTN4 Reticulon-4 1 RGS(0.312)S(0.312)GS(0.376)VDETLFALPAASEPVIR 126.26 1.4607e-07 3226900.0 14400.0 12802.0 17593.0 22390.0 18977.0 18556.0 15525.0 22073.0 19013.0 15284.0 True False 18978.9004613931 16939.996143245302 17359.705324938004 17228.331422051666 16342.371116864017 17395.690386612274 16906.694924089843 18662.12503708005 20017.988364191202 14748.91181208753 1.2868000502815988 1.1485590502590204 1.1770160094598157 1.1681086470346997 1.1080391099410167 1.1794558546587528 1.1463011739099216 1.2653221657875418 1.3572518853753928 1.0 13.848320894619276 -7.757018904422864 24.97296693556429 1.2334652707413614 1.1701545512556175 0.003785203840568241 0.09459474480917564 278.15801220653697 1571452.932249608 0.04372148203395204 0.024143132409739688 1.749770521131928e-08 7.757018904422864 -0.06331071948574385 RGSSGS(ph)VDETLFALPAASEPVIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGSSGSVDETLFALPAASEPVIR 23 1 Q9NQC3-5;Q9NQC3 Q9NQC3-5 RTN4 Reticulon-4 1 RGS(0.305)S(0.305)GS(0.386)VDET(0.003)LFALPAASEPVIR 82.50299999999999 4.4263999999999995e-05 3980900.0 23245.0 32786.0 27082.0 22482.0 31394.0 17877.0 24635.0 18335.0 18110.0 18043.0 True False 27179.919390322666 36040.777404874505 27727.73758905693 21222.406427627422 25242.571063714673 16939.498649340116 22301.394458045175 17853.725677538318 18374.82448924604 21314.053071690596 1.275211209191514 1.6909396482991776 1.300913415941758 0.9957001775422574 1.1843158585938753 0.7947572708186235 1.0463234929102232 0.8376504279822641 0.8620990305054438 1.0 14.379517341061836 -5.676283506686641 2.614421898919426 0.9513832355595178 1.491226389848799 0.6990990437479796 0.14195819226335463 0.14022353477631336 1.935395707145244 0.039986328236044956 0.07766155854461569 2.1072520903175825e-06 5.676283506686641 0.5398431542892812 RGSSPGS(ph)LEIPK ddPTM_PC-9_Lapatinib_30min_R1 1 RGSSPGSLEIPK 12 1 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 RGS(0.06)S(0.06)PGS(0.88)LEIPK 69.815 0.045905 14525000.0 25891.0 31799.0 25231.0 26324.0 57675.0 75428.0 64242.0 59255.0 90434.0 64556.0 True False 25521.789592172096 31725.37136922474 23156.604574476525 28259.95477428975 54282.66989341279 72202.12027125589 67568.13642147988 62008.203621012646 80248.37060776202 75714.41858453717 0.3370796483588702 0.4190136035159871 0.30584141049199975 0.37324403069590706 0.7169396649702162 0.9536112357600725 0.8924077828853464 0.8189748370289449 1.0598822801255823 1.0 16.208280443824087 -6.421669788777574 2.520845563621948 0.930681683575476 0.3531298686321011 0.9442152617218841 0.0670781451372021 0.06289301181179983 0.7830397794481155 0.02289818234355114 0.026125483768268638 3.7873043895898307e-07 6.421669788777574 -0.5775518149433749 down RGSTT(ph)SIPSPQSDGGDPNQPDDR ddPTM_PC-9_Lapatinib_30min_R1 1 RGSTTSIPSPQSDGGDPNQPDDR 23 1 Q8IYB1 Q8IYB1 MB21D2 Protein MB21D2 1 RGS(0.133)T(0.208)T(0.329)S(0.329)IPSPQSDGGDPNQPDDR 116.83 2.3288000000000003e-08 10623000.0 11265.0 15269.0 13471.0 9162.0 14012.0 11435.0 9931.0 11819.0 12250.0 12122.0 True False 11104.359034252004 15233.645568624566 12363.466379563763 9835.804043536036 13187.841708651922 10945.951706286944 10445.178587243803 12368.153887380788 10870.276001781247 14217.271548450299 0.7810471226078813 1.0714886830929986 0.8696089356829789 0.6918207906500985 0.9275930099323041 0.7699052289312197 0.7346823581197154 0.8699386408448344 0.7645824281218094 1.0 13.795357001946448 -5.519746342986013 24.971158590277714 0.8130429338399524 0.9373381381383478 0.12085024097420338 0.10898601115222645 183.82716268705445 1465446.2058523763 0.027270111596280004 0.04845241289366849 3.0217160893226522e-06 5.519746342986013 0.12429520429839536 RGSTTS(ph)IPSPQSDGGDPNQPDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGSTTSIPSPQSDGGDPNQPDDR 23 1 Q8IYB1 Q8IYB1 MB21D2 Protein MB21D2 1 RGS(0.184)T(0.184)T(0.184)S(0.438)IPS(0.01)PQSDGGDPNQPDDR 65.833 0.00078704 4782600.0 7874.6 11831.0 7947.7 8227.6 9944.2 7418.2 9254.0 10088.0 8131.3 5425.9 True False 9207.614249560535 13005.503491644913 8137.203309820095 7766.634246239096 7995.7053950369955 7029.176533005248 8377.394126841893 9823.200689119523 8250.204879591742 6409.57271859923 1.4365410385066664 2.0290749575093643 1.2695391201675026 1.2117241799444696 1.2474630909226043 1.0966685053136316 1.3070128844209006 1.5325827664946625 1.2871692454087282 1.0 12.646012470319791 -5.293415425160873 20.944014770657816 1.2589969697335115 1.7328073152481185 0.5212790036412658 0.1869239164404063 60.75103591407583 39791.29359685549 0.04746361783156635 0.09884604656527105 5.088439026468926e-06 5.293415425160873 0.473810345514607 RGT(ph)GQSDDSDIWDDTALIK ddPTM_PC-9_AZD4547_30min_R2 1 RGTGQSDDSDIWDDTALIK 19 1 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 1 RGT(0.463)GQS(0.463)DDS(0.073)DIWDDT(0.001)ALIK 58.158 0.021078 2703000.0 8347.8 6026.1 9787.7 13816.0 11139.0 9379.9 7914.7 10258.0 8108.6 9672.5 True False 11002.226754973415 7973.918978191731 9657.908702830435 10630.934655072168 9592.542123135809 8793.37337019748 8619.092967194452 8672.861805389715 8537.204041965011 9333.868719079863 1.1787423935461159 0.8542994569756284 1.0347165782488652 1.138963378962134 1.0277134178593252 0.9420931057475099 0.9234212764933902 0.929181892998029 0.9146479663372223 1.0 13.188259460592343 -6.746584184263234 4.911609413283414 0.935550195773669 1.0416185463441143 0.28670712088466 0.08260500934809926 0.26004839194588525 16.401417692303244 0.028549805499362077 0.027144012274235192 1.7923210926076957e-07 6.746584184263234 0.10606835057044528 RGT(ph)GQSDDSDIWDDTALIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGTGQSDDSDIWDDTALIK 19 1 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 1 RGT(0.333)GQS(0.333)DDS(0.333)DIWDDT(0.001)ALIK 52.754 0.036774 3475100.0 14610.0 10372.0 15820.0 18168.0 22742.0 21401.0 19755.0 18685.0 20105.0 14302.0 True False 17083.1844393467 11401.663613839997 16197.208797684092 17150.105861450727 18285.86835481298 20278.693885692675 17883.663386185588 18194.53854839396 20398.997590076844 16894.839385430285 1.0111480819450014 0.6748607283992605 0.958707474405006 1.0151091389623141 1.082334548298949 1.2002892376224983 1.0585281681699823 1.0769287670224617 1.207409974413161 1.0 14.044295014813244 -5.782949522638562 2.00765812237851 1.1086335437913106 0.8412682466446328 0.5163747745300156 0.09807556703216415 0.22978524961948524 1.8912181493582092 0.02856296780487287 0.05512024236814548 1.6483539659691285e-06 5.782949522638562 -0.2673652971466778 RGT(ph)GQSDDSDIWDDTALIK ddPTM_PC-9_Lapatinib_30min_R1 2 RGTGQSDDSDIWDDTALIK 19 1 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 1 RGT(0.489)GQS(0.489)DDS(0.022)DIWDDTALIK;RGT(0.422)GQS(0.289)DDS(0.289)DIWDDTALIK 76.378 0.0031785 9782500.0 58536.0 50810.0 54668.0 48876.0 53643.0 48395.0 46289.0 49094.0 58901.0 46519.7 True False 57701.265905812324 50692.35256675709 50173.408064582574 52470.50408555635 50487.824206195786 46325.25866425507 48685.61792618353 51375.08646645848 52266.949124972896 54560.56816139609 1.0575635087802917 0.9291023586265377 0.9195910115188717 0.9616927728894409 0.9253537107027059 0.8490611484693472 0.8923224146450635 0.9416156795597398 0.9579619656885093 1.0 15.735571047360228 -4.761508486738612 6.529521038966564 0.925383034882951 1.0612188521660395 0.48413303428539967 0.03893915411354982 0.10324487233330346 20.98855726550976 0.009991012859963245 0.06241268363052983 1.731775189042289e-05 4.761508486738612 0.13583581728308847 RGT(ph)S(ph)ET(ph)QRMYMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RGTSETQRMYMK 12 2 Q9C0G0-3;Q9C0G0-2;Q9C0G0 Q9C0G0-3 ZNF407 Zinc finger protein 407 3 RGT(1)S(0.992)ET(0.992)QRMY(0.016)MK 66.98899999999999 0.034924000000000004 0.0 6335.1 6075.0 6154.6 8301.6 8124.8 6571.8 8439.3 6320.2 5887.0 4776.2 True False 7407.5073060715395 6678.085851723681 6301.349005450483 7836.488266150335 6532.803764364816 6227.163239007289 7639.868408759104 6154.301446805432 5973.086237890194 5642.087251621603 1.312901941376843 1.1836197410460676 1.1168471390865853 1.3889342572463825 1.1578700351518332 1.1036985004472464 1.3540854772430742 1.0907845221706935 1.0586660523857474 1.0 12.462013261203877 -7.954026885898397 9.834856542444768 1.0443395062829126 1.223361128883082 0.4504651615080567 0.09285887230756172 0.3562481037625323 73.41980916628883 0.05020904706919283 0.024042077611063608 1.1116629053592993e-08 7.954026885898397 0.1790216226001693 RGTGQS(ph)DDSDIWDDTALIK ddPTM_PC-9_AZD4547_30min_R2 1 RGTGQSDDSDIWDDTALIK 19 1 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 1 RGT(0.242)GQS(0.747)DDS(0.011)DIWDDTALIK 104.3 0.00012002 6205000.0 18928.0 17273.0 27044.0 37096.0 27143.0 23101.0 18607.0 28153.0 20390.0 24132.0 True False 24946.710273142267 22856.159458074984 26685.378889764313 28544.09032748675 23374.66297228434 21656.49081812514 20262.986953464733 23802.600741580893 21467.773772989993 23287.146025209135 1.0712652484824288 0.9814925123642205 1.1459274082309818 1.2257444642029895 1.0037581654265604 0.9299761677399733 0.8701361228005078 1.022134731143686 0.9218722530339437 1.0 14.507246219288273 -6.507196990704089 15.483613730859979 0.9476834884091805 1.1018903934186628 0.534494438829721 0.06927193352498587 4.217900132337306 4164.365456780765 0.023263045758453553 0.02535491579608505 3.1103052204127013e-07 6.507196990704089 0.1542069050094823 RGTGQS(ph)DDSDIWDDTALIK ddPTM_PC-9_Lapatinib_30min_R1 1 RGTGQSDDSDIWDDTALIK 19 1 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 1 RGT(0.234)GQS(0.72)DDS(0.046)DIWDDTALIK 68.445 0.0038703 5077500.0 27219.0 18845.0 28006.0 27451.0 22667.0 24670.0 21080.0 20388.0 25652.0 18164.0 True False 26830.852068646735 18801.36556033334 25703.454786286307 29469.838113851518 21333.771625036614 23614.921608578836 22171.41925476785 21335.300910053258 22762.801632464707 21303.623197991375 1.259450179872525 0.8825430953973142 1.2065297319335695 1.3833251668021476 1.0014151783837446 1.108493207427992 1.04073466981233 1.0014869635914734 1.068494378675028 1.0 14.378811196162328 RGTGQSDDS(ph)DIWDDTALIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RGTGQSDDSDIWDDTALIK 19 1 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 1 RGT(0.073)GQS(0.055)DDS(0.652)DIWDDT(0.219)ALIK;RGT(0.153)GQS(0.135)DDS(0.688)DIWDDT(0.024)ALIK 47.732 0.035419 5338000.0 24196.2 22067.1 22496.0 27854.1 31601.0 32385.7 31614.0 26752.5 29865.7 26274.9 True False 28292.13876326629 24257.775851616738 23032.38995655508 26293.52508121061 25409.010899676607 30687.336880233495 28619.293054460733 26050.275221616783 30302.429362146642 31038.331378006027 0.9115225434868027 0.7815425241836925 0.7420627634923695 0.847130754581813 0.818633276068494 0.9886915796632918 0.9220628746408887 0.8392936754350199 0.9762905419464382 1.0 14.92176337981343 -6.742131705640889 24.24314791100257 0.9337732665314095 0.8151894653911205 0.5222638439252998 0.05921574851117782 148.67089109338718 186673.79503211554 0.019747576263266377 0.019715095745562652 1.8107908626672617e-07 6.742131705640889 -0.11858380114028899 RGTLDQPPNQEDK ddPTM_PC-9_AZD4547_30min_R2 1 RGTLDQPPNQEDK 13 1 Q6NV74 Q6NV74 KIAA1211L Uncharacterized protein KIAA1211-like 0 61.375 0.033969 135540000.0 9357.3 2513.2 11499.0 30990.0 25546.0 11773.0 9563.4 13289.0 6709.2 15235.0 False True 12332.726756069003 3325.542751695365 11346.51574668687 23845.734290727156 21999.378856057778 11036.832448889105 10414.524073239349 11235.490400840705 7063.834614896731 14701.627287173105 0.8388681412722983 0.22620235751703752 0.7717863828983402 1.6219792424973332 1.4963907345992797 0.7507218237343383 0.7083926064651241 0.7642344742777869 0.4804797779807542 1.0 13.843688231835614 -11.002260311638757 2.8999627826652556 1.0042401484032561 0.8622610090896313 0.011753065377358651 0.3980048225798999 335301066.08099943 369717155.69854987 11420744.013744906 0.10997092350424129 9.948089603710446e-12 11.002260311638757 -0.14197913931362482 RGTLVAER ddPTM_PC-9_AZD4547_30min_R2 2 RGTLVAER 8 1 Q9BR76;A0A087WW53;F5H390 Q9BR76 CORO1B Coronin-1B;Coronin 0 ; 89.88600000000001 0.0062577 4089800.0 10778.7 12330.8 15649.2 25539.0 18653.0 17357.4 14279.7 18859.9 15150.5 17009.9 False True 14206.102389112348 16316.489958063517 15441.681382994373 19651.378123616694 16063.352924216917 16272.039034090527 15550.565636555604 15945.535812387365 15951.324499641234 16414.388578410602 0.8654664364286615 0.9940358046308317 0.9407405770388789 1.1972043935564933 0.9786141498651133 0.9913277583481054 0.9473740409075511 0.9714364769797209 0.971789136308225 1.0 14.002673391335254 -4.549089361484532 2.0955889696218093 1.0022573725491912 0.7439866099820468 0.2511766203610596 0.06892041631908892 2.577341028922492 6.960895410755567 0.0188270921300474 1.5902896639993336 2.8242987805657575e-05 4.549089361484532 -0.25827076256714443 RGTLVAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RGTLVAER 8 1 Q9BR76;A0A087WW53;F5H390 Q9BR76 CORO1B Coronin-1B;Coronin 0 ; 117.01 0.0022559 2430300.0 9945.9 12598.400000000001 12555.7 15404.0 17999.9 15757.3 14297.9 14887.2 11288.9 12100.0 False True 11629.544429520754 13849.085892075 12855.07550575741 14540.963820441808 14472.948808363311 14930.959448858697 12943.49940416822 14496.426774292246 11453.978805999433 14293.634216452709 0.8136170447215272 0.9688988596150019 0.8993566864164297 1.0173034793141977 1.0125450665096916 1.0445880468714104 0.905542929681913 1.0141876135046266 0.8013342605910059 1.0 13.803085153888118 -4.050556818392914 1.537612113007201 0.9681899120486823 3.193261743260229e-09 0.2758703695590079 0.07097089963062976 12.060787871400834 5.070368113681085 0.019228131835778473 30.58134764094457 8.90108978160447e-05 4.050556818392914 -0.9681899088554206 RGTLVAER ddPTM_PC-9_Lapatinib_30min_R1 4 RGTLVAER 8 1 Q9BR76;A0A087WW53;F5H390 Q9BR76 CORO1B Coronin-1B;Coronin 0 ;;; 89.88600000000001 0.0062577 5557180.0 27483.6 22973.2 21653.1 22819.3 21696.0 22140.2 19846.5 21565.899999999998 22156.9 19621.0 False True 27091.678824125014 22920.006966869198 19872.86570138314 24497.507444953284 20419.883935977174 21193.31525732698 20874.0546603297 22567.93044418863 19661.356599499366 23012.463706660903 1.1772611211672825 0.9959823189307218 0.8635696705360142 1.0645321490659228 0.8873401907882938 0.9209494266879659 0.9070760491536486 0.9806829347722729 0.8543786032700372 1.0 14.490127825828091 -4.806260708095895 3.3347212324795583 0.9351182874326186 1.2028272020736903 0.5810443007366104 0.061828098090959446 0.1943569768462196 3.4898766080855474 0.014685840646724676 0.13010662500154235 1.5622095626796907e-05 4.806260708095895 0.2677089146410717 RGVACTQPR ddPTM_PC-9_Lapatinib_30min_R1 2 RGVACTQPR 9 1 O43143 O43143 DHX15 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 0 ; 77.192 0.014818000000000001 1471090.0 6793.6 6801.799999999999 6645.5 6288.5 6728.7 7179.5 6573.1 5180.5 6195.9 3817.6000000000004 False True 6696.722018206346 6786.050850001344 6099.132642371834 6750.977267821042 6332.931095133183 6872.449521231926 6913.422955574689 5421.204942345057 5498.052496280527 4477.467073367752 1.4956496404046962 1.5156003916511613 1.362183695029238 1.5077670381935955 1.414400372210852 1.5348967191986014 1.5440477489373738 1.2107749434028707 1.227938119072562 1.0 12.128467107545859 -8.193087765695068 1.4195256103954648 1.0304956641202176 1.479040396091083 0.8080954269446627 0.07544900595034003 0.1623962426158292 0.6109334093094188 0.06879566706272743 0.021655318487598968 6.410800089288153e-09 8.193087765695068 0.4485447319708653 RGVSS(ph)PVETR ddPTM_PC-9_Lapatinib_30min_R1 2 RGVSSPVETR 10 1 A8MVZ6;Q96G01-4;Q96G01-3;Q96G01 A8MVZ6 BICD1 Protein bicaudal D homolog 1 1 RGVS(0.243)S(0.729)PVET(0.029)R;RGVS(0.224)S(0.752)PVET(0.024)R 65.234 0.022619999999999998 6367400.0 19793.5 21216.0 22940.0 17461.1 18083.8 20078.8 22013.0 16086.900000000001 26121.1 17880.7 True False 19511.241060316646 21166.875655507156 21053.96175096079 18745.247542522062 17020.14643811872 19220.07652996889 23152.725429563772 16834.356102115755 23179.066650622728 20971.3551704649 0.9303757864820957 1.009323216523347 1.0039390196687064 0.8938500821788576 0.8115902048184811 0.9164918706368375 1.1040166570718812 0.8027309616034969 1.10527271424343 1.0 14.35613247105256 RHEHPPNPPVS(ph)PGK ddPTM_PC-9_AZD4547_30min_R2 1 RHEHPPNPPVSPGK 14 1 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 RHEHPPNPPVS(1)PGK 48.907 0.040859 6714900.0 49359.0 54758.0 52262.0 55618.0 53578.0 57572.0 54795.0 54479.0 56153.0 52330.0 True False 65054.13526902094 72457.45264894745 51568.971732615835 42796.129389534144 46139.61952359913 53972.01373884683 59671.64884801954 46060.522352878404 59121.13294137847 50497.94262801236 1.2882531818817888 1.4348594987858705 1.0212093611910706 0.8474826331992812 0.9136930560415433 1.0687962901068235 1.1816649499482443 0.9121267116202786 1.1707632007285507 1.0 15.623936990763843 -5.270198482996221 24.387315267261343 1.0096775606461716 1.3615563415034257 0.6260342717202052 0.10725344228775052 255.807318188366 712227.23686163 0.028942757667232262 0.06181018967705749 5.367864160334463e-06 5.270198482996221 0.3518787808572541 RHEHPPNPPVS(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RHEHPPNPPVSPGK 14 1 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 RHEHPPNPPVS(1)PGK 51.089 0.036000000000000004 4294400.0 30062.0 35285.0 29534.0 41575.0 38188.0 31743.0 37447.0 30522.0 29868.0 30021.0 True False 35150.90284843536 38787.86160955886 30238.202568318717 39245.687537968624 30705.33553485175 30078.341199642186 33899.74906719779 29720.829840732174 30304.762995295456 35463.56965389476 0.9911834367349126 1.0937382217331022 0.8526553548733871 1.1066479748368618 0.8658275473822631 0.8481475918298838 0.9559034636964351 0.8380665040432022 0.8545322225329693 1.0 15.114050140342602 -6.289948953986686 24.93637905119285 0.8864774659428035 1.0056477717772139 0.3355429287633096 0.08033923523062718 765.1920117107152 669285.8892261826 0.023646544818662393 0.02681775438579563 5.129216681274262e-07 6.289948953986686 0.11917030583441035 RHES(ph)EEGDSHR ddPTM_PC-9_AZD4547_30min_R2 1 RHESEEGDSHR 11 1 Q6UN15;Q6UN15-5;Q6UN15-3;H0Y8P7 Q6UN15;H0Y8P7 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 RHES(0.995)EEGDS(0.005)HR 60.364 0.023433000000000002 3421400.0 3576.5 3784.7 3504.2 1709.0 3337.9 3113.5 3641.6 3690.2 6040.7 3988.1 True False 4713.75260417864 5008.030261157669 3457.732018396395 1315.0164537867938 2874.4902013479677 2918.81235280865 3965.6953452860294 3119.964382360025 6359.999069666528 3848.4778328831667 1.2248355866577083 1.3013015739279443 0.8984674379184259 0.3416978116778243 0.746916138320195 0.7584329388281708 1.0304581492977047 0.8107008843084953 1.6526011960686813 1.0 11.910072222110143 -8.23849204450932 24.810868194739022 1.326300693682207 0.8805234969881953 0.2621085112240604 0.2931410920768069 881.0823219729688 952637.4415514694 0.21181172719942706 0.07994145323711717 5.774414503017575e-09 8.23849204450932 -0.4457771966940117 RHES(ph)EEGDSHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RHESEEGDSHR 11 1 Q6UN15;Q6UN15-5;Q6UN15-3;H0Y8P7 Q6UN15;H0Y8P7 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 RHES(1)EEGDSHR;RHES(0.999)EEGDS(0.001)HR 77.062 0.0073057 7720600.0 4043.26 8239.6 8547.7 3151.48 9686.1 8517.9 3705.2400000000002 4350.7699999999995 9631.8 12145.699999999999 True False 4727.704059974874 9057.573034380648 8751.509585332764 2974.912792836014 7788.178237250642 8071.206329094044 3354.2528435854365 4236.566897521861 9772.646853424627 14347.619264691708 0.3295113964732364 0.6312944933429184 0.6099624909109136 0.20734539563347806 0.5428202472877642 0.5625467319833757 0.23378462877391598 0.2952801311049352 0.6811336900662185 1.0 13.808523746417718 -8.546266556059141 4.492111909404574 0.9995803039237622 0.4355330041286051 0.5947759673812103 0.1485412613142792 0.13033153029978983 9.556427708255125 0.14791749542441235 0.03859378970506759 2.842715803880059e-09 8.546266556059141 -0.5640472997951571 RHES(ph)EEGDSHR ddPTM_PC-9_Lapatinib_30min_R1 1 RHESEEGDSHR 11 1 Q6UN15;Q6UN15-5;Q6UN15-3;H0Y8P7 Q6UN15;H0Y8P7 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 RHES(0.995)EEGDS(0.005)HR 59.248000000000005 0.025172999999999997 6697300.0 5650.1 11257.0 14138.0 10913.0 23608.0 13107.0 24242.0 30089.0 12849.0 13620.0 True False 5569.528537898563 11230.935108128017 12975.62821425822 11715.578424700805 22219.423855113797 12546.444163909311 25497.132142983024 31487.04478529493 11401.810314031618 15974.198852490774 0.34865776927711994 0.70306719052623 0.812286633844864 0.7334063218371704 1.3909570088799312 0.7854193052037166 1.596144656669739 1.9711188696255222 0.7137641404942066 1.0 13.963455957637427 -5.890624950726547 0.8079587159028753 1.341360629739705 0.4332953072395608 0.3775816458137752 0.3698504224858654 0.8155486836094565 1.0138959173765283 0.1778069789101033 0.5033311260088927 1.2863970908868438e-06 5.890624950726547 -0.9080653225001442 RHFS(ph)S(ph)VS(ph)TET(ph)FVPK ddPTM_PC-9_AZD4547_30min_R2 1 RHFSSVSTETFVPK 14 1 A0A2R8YFC3;A0A2R8Y4J4;Q9NWS8-3;Q9NWS8 A0A2R8YFC3 RMND1 Required for meiotic nuclear division protein 1 homolog 4 RHFS(0.997)S(0.997)VS(0.535)T(0.535)ET(0.936)FVPK 62.104 0.038548 0.0 14355.0 14118.0 13450.0 9255.0 11293.0 14993.0 17230.0 13850.0 13008.0 10140.0 True False 18919.59139745125 18681.36740746268 13271.644211926116 7121.40273832462 9725.161881369311 14055.48533986192 18763.43662106718 11709.80074133823 13695.576323641662 9785.001686375794 1.9335297022783409 1.9091838720348708 1.3563251839194845 0.727787584159556 0.993884538099794 1.4364315705159418 1.9175711177640944 1.1967091183686194 1.399649868503424 1.0 13.256356384152468 -5.287073615844515 4.729890317111767 1.2586668432329695 1.9305476799738233 0.4415189194183837 0.30185468743250277 0.18579878277125042 11.130827545889295 0.08784936140300752 0.2068681925256028 5.163288406321939e-06 5.287073615844515 0.6718808367408537 RHGAPAAPS(ph)PPPR ddPTM_PC-9_AZD4547_30min_R2 3 RHGAPAAPSPPPR 13 1 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 RHGAPAAPS(1)PPPR;RHGAPAAPS(1)PPPR;RHGAPAAPS(1)PPPR 125.41 6.5058e-05 63028700.0 47407.5 64668.9 77600.0 98579.0 111090.3 85393.6 64290.6 80647.4 68890.9 86088.0 True False 62482.09886274259 85571.85725573469 76570.97329706082 75853.13458036764 95667.32940315943 80053.92469272533 70012.33885260498 68185.19742288832 72532.33233044017 83074.08532314785 0.752125029360179 1.0300668002888123 0.9217191257563566 0.9130781793781826 1.1515905234589754 0.9636449728134294 0.8427699032768847 0.8207757829370782 0.8731041942658583 1.0 16.342110882940446 -10.30092689944711 6.507855854362125 1.0000000008370065 0.9250079065446052 0.04664013985851678 0.10687980171520642 1.4022047941937129e-09 2.466080849631632e-10 0.10770233735931381 0.02612165351469368 5.001187079954149e-11 10.30092689944711 -0.07499209429240128 RHGAPAAPS(ph)PPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 RHGAPAAPSPPPR 13 1 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 RHGAPAAPS(1)PPPR;RHGAPAAPS(1)PPPR;RHGAPAAPS(1)PPPR;RHGAPAAPS(1)PPPR;RHGAPAAPS(1)PPPR;RHGAPAAPS(1)PPPR 107.63 0.00045208 63951900.0 49688.0 44988.3 60363.899999999994 71316.4 88686.3 79744.1 61287.8 65579.2 66373.4 55835.49999999999 True False 58099.19701726613 49454.441106683225 61803.20430736555 67320.7733188883 71308.85615493146 75562.17901453511 55482.175898753034 63857.81548690591 67343.98540886394 65958.03415642522 0.8808509495519353 0.7497864625467417 0.9370079793584186 1.0206607000935053 1.0811246433727286 1.1456099318444335 0.8411738859161907 0.968158258559701 1.0210126221947704 1.0 16.009260780219304 -5.481708217277299 4.143465509708725 1.0101085790914737 0.816763703444362 0.48862870731873054 0.07933693121244571 0.18560653453980686 6.84904999193572 0.022728721564326673 0.04762957111182491 3.298312363692305e-06 5.481708217277299 -0.19334487564711167 RHGAPAAPS(ph)PPPR ddPTM_PC-9_Lapatinib_30min_R1 4 RHGAPAAPSPPPR 13 1 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 RHGAPAAPS(1)PPPR;RHGAPAAPS(1)PPPR;RHGAPAAPS(1)PPPR;RHGAPAAPS(1)PPPR 117.07 0.00012118 66762800.0 66259.8 59673.3 61520.2 52978.200000000004 61215.4 53600.9 52767.1 57576.9 70819.5 40698.399999999994 True False 65314.9231014408 59535.130140166635 56462.2466308395 56874.39355809438 57614.83052610696 51308.51445680066 55499.122246596744 60252.132968807455 62843.062147603865 47733.06421279075 1.3683371092681442 1.2472513785153847 1.182874964388095 1.1915093760700592 1.207021411180811 1.0749051061978925 1.1626976638077422 1.2622724721842191 1.316552020784875 1.0 15.542701332379975 -4.714148599849648 1.6858761974916978 1.1807238006432943 1.458043295027735 0.33495133193882765 0.08375089127264906 1.4334136854340511 3.552113932532395 0.023268584283593876 0.684603790763741 1.9313073804794856e-05 4.714148599849648 0.2773194943844408 RHNSWS(ph)SSSR ddPTM_PC-9_Lapatinib_30min_R1 1 RHNSWSSSSR 10 1 H3BQ37;H3BPW9;Q96F86 H3BQ37 EDC3 Enhancer of mRNA-decapping protein 3 1 RHNS(0.133)WS(0.388)S(0.388)S(0.077)S(0.013)R 63.292 0.025577000000000003 6023500.0 2632.3 801.35 2218.0 1156.9 3133.8 2896.4 1141.5 2103.0 4232.7 2463.6 True False 2594.7629192953013 799.494523309797 2035.644601727594 1241.9822853052647 2949.476045287853 2772.5277238381736 1200.601284597604 2200.71305737895 3755.9687536930232 2889.4299774593424 0.8980189655181954 0.27669627904005745 0.7045142528484194 0.4298364365961662 1.0207812849928652 0.9595414131738329 0.4155149264607842 0.7616426335114108 1.2998995590803772 1.0 11.496569192680388 -7.599092534916314 0.4783043076479701 1.0795657299986263 0.578151375621785 0.23935135991223788 0.26704593847287716 1.4424758646441063 0.7657546156402111 0.2816860391090219 0.21939618088948235 2.5171405446926195e-08 7.599092534916314 -0.5014143543768413 RHNSWSSS(ph)SR ddPTM_PC-9_AZD4547_30min_R2 1 RHNSWSSSSR 10 1 H3BQ37;H3BPW9;Q96F86 H3BQ37 EDC3 Enhancer of mRNA-decapping protein 3 1 RHNS(0.027)WS(0.115)S(0.185)S(0.664)S(0.01)R 65.895 0.021828999999999998 10819000.0 2337.7 942.37 4238.5 6842.1 6303.8 4664.9 3650.2 6034.3 3414.1 3819.9 True False 3081.0399728193483 1246.972673450248 4182.294720613298 5264.75955439123 5428.626181508531 4373.203065558716 3975.060728625623 5101.837589419302 3594.5623559767087 3686.1664636870687 0.8358385339270745 0.3382844170859745 1.1345919295326612 1.4282479118225122 1.4727023955609904 1.1863824134476126 1.0783725498521273 1.3840497003263972 0.9751492211182635 1.0 11.847905507804649 -5.376519481937727 5.705159636786194 1.239752570478896 0.5925842978628402 0.609852683436537 0.1984354253362736 0.12883320698564135 5.514322834175263 0.05090603640165328 0.10823750706933385 4.202236765164853e-06 5.376519481937727 -0.6471682726160559 RHNSWSSS(ph)SR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RHNSWSSSSR 10 1 H3BQ37;H3BPW9;Q96F86 H3BQ37 EDC3 Enhancer of mRNA-decapping protein 3 1 RHNS(0.161)WS(0.161)S(0.161)S(0.493)S(0.023)R 54.199 0.043711 5097400.0 411.09 620.38 1117.0 1258.2 2320.1 2439.5 874.26 2244.2 2157.6 574.0 True False 480.6794176023978 681.9672264514138 1143.6335162460896 1187.7071331394372 1865.493059977206 2311.5683255056883 791.4437637057263 2185.2921279264506 2189.150818221825 678.0616562184999 0.7089022262121584 1.0057599042758072 1.686621719069103 1.7516211427780664 2.7512144992550143 3.40908279402958 1.1672150407671626 3.2228516505617857 3.228542416674257 1.0 9.405272653514485 -5.599167374472487 1.2984039981602502 2.5410282989738855 0.7303700361810931 0.3781707260321965 0.7910388719573945 0.5138208021262125 1.6263819191904598 0.25925679467445817 0.8312654051999819 2.5167068172137124e-06 5.599167374472487 -1.8106582627927925 RHNSWSSS(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 1 RHNSWSSSSR 10 1 H3BQ37;H3BPW9;Q96F86 H3BQ37 EDC3 Enhancer of mRNA-decapping protein 3 1 RHNS(0.047)WS(0.262)S(0.262)S(0.368)S(0.061)R 68.171 0.019109 5115400.0 2993.9 817.08 2218.6 777.86 2545.6 2764.1 2855.6 2478.3 3464.0 1235.4 True False 2951.206436985983 815.1881014612452 2036.195272043661 835.0664192648917 2395.8728128421594 2645.885886431807 3003.4489954418905 2593.450865478959 3073.847842462878 1448.937243932974 2.0368076321754773 0.562611048114486 1.4053025971757356 0.5763302881208295 1.6535380140680471 1.8260872908821457 2.0728634093836753 1.7898986835615693 2.121449949149813 1.0 10.500779395204042 -6.474320513281457 10.289379439874354 1.8209054470335357 1.1207735184966543 0.26515407311499506 0.48546203487978723 0.7915973548481844 165.4043313797689 0.14059081329719483 0.15885998199437898 3.3548992823559787e-07 6.474320513281457 -0.7001319285368814 RHPPLYQAGLTPPLS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 1 RHPPLYQAGLTPPLSPPK 18 1 Q9ULL5;Q9ULL5-2;A0A3Q5ADB5 Q9ULL5 PRR12 Proline-rich protein 12 1 RHPPLYQAGLTPPLS(1)PPK 90.561 0.00060824 7657800.0 69758.0 46875.0 49713.0 51892.0 63747.0 49332.0 48873.0 64267.0 54167.0 49855.0 True False 68763.23812794957 46766.46381749141 45625.789037729424 55708.3107866374 59997.52679142408 47222.18535850875 51403.40480257443 67253.07943821824 48066.14205620284 58472.370322388204 1.1759953931886553 0.7998044813241515 0.7802965535033216 0.9527287927526945 1.0260833699852923 0.8075982741617724 0.8791058840125868 1.1501685166415774 0.8220317013178963 1.0 15.83546745526938 RHQYSDYDYHSS(ph)SEK ddPTM_PC-9_AZD4547_30min_R2 1 RHQYSDYDYHSSSEK 15 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 RHQYSDYDYHS(0.126)S(0.437)S(0.437)EK 57.93600000000001 0.022251 4788400.0 14335.0 11354.0 27508.0 48808.0 35282.0 35901.0 21738.0 38865.0 28817.0 33423.0 True False 18893.231813477087 15023.95846042861 27143.22594659211 37556.06967608296 30383.703311650737 33656.10479466301 23672.639887914025 32859.30727885275 30340.207788928514 32252.870943169455 0.5857844979681821 0.4658177092793161 0.841575498640704 1.1644256333725422 0.9420464728609045 1.0435072540973516 0.7339700062554413 1.0188025536316396 0.9406978945343777 1.0 14.977139965236514 -5.395588533364537 4.2230199685230065 0.9715726962311461 0.5290962976664497 0.7355055342241981 0.10656387410250698 0.10833373990387594 3.158347353224829 0.028300908258678332 0.06245101026069845 4.0217166269379026e-06 5.395588533364537 -0.44247639856469634 RHS(ph)DENDGGQPHK ddPTM_PC-9_AZD4547_30min_R2 1 RHSDENDGGQPHK 13 1 F2Z2T1;Q09161 F2Z2T1 NCBP1 Nuclear cap-binding protein subunit 1 1 RHS(1)DENDGGQPHK 69.878 0.010819 4028200.0 9407.4 6293.6 6524.6 7976.7 6786.7 10134.0 9263.3 6340.4 9981.7 8176.6 True False 12398.757513924267 8327.883121944122 6438.079540902097 6137.795053786493 5844.4838519692785 9500.319377987105 10087.715754610075 5360.636867897543 10509.312283955567 7890.339722763349 1.5713844966845083 1.055453049495255 0.8159445305413742 0.7778872988293739 0.7407138421566503 1.2040444026229977 1.2784894071807043 0.6793924034008697 1.3319213941621013 1.0 12.945871702238552 -4.77398809773636 4.044965772171282 0.9682326900212498 1.6282771485133167 0.39325088951247955 0.21913357570260927 0.23716016218032138 7.417732414400672 0.05569080918705372 0.46301180490118415 1.6827201770253578e-05 4.77398809773636 0.6600444584920669 RHS(ph)EQVANGPTPPPR ddPTM_PC-9_AZD4547_30min_R2 2 RHSEQVANGPTPPPR 15 1 A6ND36;A6ND36-2;K7EKG0 A6ND36 FAM83G Protein FAM83G 1 RHS(1)EQVANGPTPPPR;RHS(1)EQVANGPTPPPR 109.55 0.00028363 16104200.0 11915.5 10340.5 11263.1 18805.3 16197.3 11043.3 13330.0 16612.7 13487.1 14639.900000000001 True False 15704.381142203441 13682.864405501334 11113.743934821194 14470.028623988752 13948.584480749414 10352.760705242248 14516.344176368297 14045.588936868568 14200.000571539633 14127.361557038748 1.1116287410637526 0.968536435501932 0.7866822045963661 1.024255560075142 0.9873453315704048 0.732816291523603 1.0275339891146018 0.9942117556884188 1.0051417254529522 1.0 13.78620443092519 RHS(ph)EQVANGPTPPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RHSEQVANGPTPPPR 15 1 A6ND36;A6ND36-2;K7EKG0 A6ND36 FAM83G Protein FAM83G 1 RHS(1)EQVANGPTPPPR 68.676 0.012518000000000001 6618000.0 4852.4 6280.4 4965.5 6018.8 6189.8 6333.6 4321.8 5949.2 5831.3 6217.1 True False 5673.815480731413 6903.876606282369 5083.896351763615 5681.586149212877 4976.953123851087 6001.454866334424 3912.4078168775986 5793.03980369844 5916.571730764242 7344.21101546348 0.7725561627770506 0.9400433336877205 0.6922317919595858 0.7736142299356743 0.6776702239862046 0.8171680870413666 0.5327199625174024 0.7887899451011147 0.8056102579714421 1.0 12.842391795836082 -8.720255878123186 2.2219084652075023 0.9995474482579213 0.7478977409065799 0.3645139005515504 0.09942221829174047 0.8769587524054117 7.5813283579555035 0.09635637467555934 0.026352220743726725 1.904338387082776e-09 8.720255878123186 -0.2516497073513414 RHS(ph)EQVANGPTPPPR ddPTM_PC-9_Lapatinib_30min_R1 2 RHSEQVANGPTPPPR 15 1 A6ND36;A6ND36-2;K7EKG0 A6ND36 FAM83G Protein FAM83G 1 RHS(1)EQVANGPTPPPR;RHS(1)EQVANGPTPPPR 111.81 0.00017603 11831700.0 14034.9 10508.099999999999 12544.6 13761.900000000001 17048.9 13755.900000000001 11339.1 16282.6 17677.6 18549.5 True False 13834.759752314561 10483.769140065735 11513.231411556348 14773.996034352604 16046.117221427048 13167.592223569083 11926.183115357584 17039.149038553718 15686.562534619454 21755.756359344894 0.6359126073946874 0.4818848385182698 0.5292039137315947 0.679084458858937 0.7375573138616555 0.6052463543936095 0.548185175379336 0.7832018688348098 0.7210304378997837 1.0 14.409109553950648 -14.522878073876118 0.125696410952211 2.277233922656442 0.4630370916208606 0.7062548523413604 0.07747215809117093 85.04560392704126 0.6799922466816893 27.122870535272686 0.6918498413872015 3.0000046378996265e-15 14.522878073876118 -1.8141968310355816 RHS(ph)EVETDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RHSEVETDSK 10 1 Q9NX58 Q9NX58 LYAR Cell growth-regulating nucleolar protein 1 RHS(1)EVETDSK;RHS(1)EVETDSK;RHS(0.999)EVET(0.001)DSK 69.314 0.017743000000000002 14806100.0 28284.8 30471.8 30333.399999999998 26208.7 76009.9 83441.1 38929.299999999996 66229.0 89702.4 109362.3 True False 33072.85798973533 33496.83892288951 31056.66329606009 24740.31150875186 61116.30573663263 79065.30182633855 35241.63488027511 64490.55892542596 91014.12789973206 129188.81927850923 0.25600402708562453 0.2592858972623319 0.24039745443533456 0.19150505165169082 0.4730773613223929 0.6120135029323794 0.27279167870015214 0.49919613234017746 0.7045046808851237 1.0 16.979121690990056 -8.96999105151613 0.23147471356819949 1.2264268736290511 0.1304339833525432 0.8024338786960075 0.11001570603138307 2.1892683289424677 0.29184580785316716 0.743750397943829 0.31026588191408 1.071541383740564e-09 8.96999105151613 -1.095992890276508 down RHS(ph)EVETDSK ddPTM_PC-9_Lapatinib_30min_R1 2 RHSEVETDSK 10 1 Q9NX58 Q9NX58 LYAR Cell growth-regulating nucleolar protein 1 RHS(1)EVETDSK;RHS(1)EVETDSK 115.37 0.0012525000000000001 19186000.0 27484.0 22680.0 23729.0 27687.0 69801.0 48472.0 160976.0 126655.0 47732.0 62559.0 True False 27092.073120051668 22627.48585345505 21778.09321658885 29723.194341124447 65695.442414046 46398.96555375079 169310.54961838285 132539.85367680952 42355.919519756986 73372.23979537231 0.36924146237880556 0.30839300962544963 0.296816524578311 0.4051013629135406 0.8953719090116901 0.6323776633118026 2.3075559651793744 1.8064032670455425 0.5772744519982397 1.0 16.162946705766284 -7.081788976414821 8.507925367536833 1.4912452226244621 0.46737482099404476 0.5030208728271736 0.45757312407385203 0.28780666663902515 27.722226642477036 0.1789766127384978 0.13871552973421433 8.283445583660358e-08 7.081788976414821 -1.0238704016304174 RHS(ph)IAIGEVPACR ddPTM_PC-9_Lapatinib_30min_R1 1 RHSIAIGEVPACR 13 1 Q8WUY9-2;Q8WUY9 Q8WUY9-2 DEPDC1B DEP domain-containing protein 1B 1 RHS(1)IAIGEVPACR 81.594 0.028776 0.0 27355.0 42674.0 20941.0 38827.0 39044.0 26785.0 58326.0 56771.0 41577.0 28753.0 True False 26964.91268370737 42575.190974882746 19219.31181459763 41682.467103075054 36747.50868345747 25639.467988884626 61345.83488869022 59408.78791272488 36894.16043478034 33722.917739035765 0.7996020063380902 1.2625002173403306 0.5699184146320302 1.236027897278466 1.0896894796537906 0.7602980319584213 1.819114092185437 1.7616740156489066 1.09403820631077 1.0 15.041441744581855 -7.2525550830389225 24.99806278137291 1.4821794199567255 0.9687383681840228 0.3395300195319816 0.3127736701481759 666.4229805561772 1875141.633904941 0.11705125050623691 0.08927607838075169 5.590426178066083e-08 7.2525550830389225 -0.5134410517727027 RHS(ph)LEVMNSMVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RHSLEVMNSMVR 12 1 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 RHS(1)LEVMNSMVR 44.691 0.045913999999999996 8010500.0 44214.0 25423.0 34107.0 46432.0 50976.0 41252.0 36862.0 42737.0 41405.0 36635.0 True False 51698.55693369435 27946.827425246287 34920.24023151778 43830.56557457506 40987.61873427782 39088.67250000437 33370.164502231026 41615.19903359451 42010.4697944358 43276.63549749956 1.1946066587519584 0.6457717219459216 0.8069074647343 1.0127997491188405 0.9471073308516786 0.9032280825588402 0.7710896218852107 0.9616089272004278 0.9707425106293921 1.0 15.401300722065598 -7.975126121557644 24.969433146175174 0.9789729010308318 0.8890373019053878 0.06450421930696437 0.1387833807372147 584.9501386216211 587197.0638932431 0.0745537746137954 0.03581241620567174 1.0589461566060233e-08 7.975126121557644 -0.08993559912544402 RHS(ph)PPIEK ddPTM_PC-9_AZD4547_30min_R2 2 RHSPPIEK 8 1 Q8IZD4;Q8IZD4-2;F5GZK9 Q8IZD4 DCP1B mRNA-decapping enzyme 1B 1 RHS(1)PPIEK;RHS(1)PPIEK 85.92399999999999 0.0058961000000000005 27289000.0 199791.0 209766.0 255559.0 367000.0 273342.0 278426.0 234504.0 309020.0 249682.0 262421.0 True False 263320.38208904106 277568.7573022962 252170.12068071606 282393.82009347726 235393.18152636584 261015.97820558862 255374.40170555701 261268.0595731658 262879.6807840943 253233.72066473632 1.0398314308135084 1.0960971413036171 0.9957999275087523 1.115150933896939 0.9295491173468556 1.0307315215383794 1.008453380676165 1.0317269709868788 1.0380911361016119 1.0 17.950110001622555 -6.2432352377477525 24.98849802842137 1.0093284027106117 1.059466802498989 0.29797512008224614 0.041377689414353214 1128.6038437415996 1549214.1787595758 0.011694077879963188 0.01507380343717016 5.71169176268133e-07 6.2432352377477525 0.05013839978837731 RHS(ph)PPIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RHSPPIEK 8 1 Q8IZD4;Q8IZD4-2;F5GZK9 Q8IZD4 DCP1B mRNA-decapping enzyme 1B 1 RHS(1)PPIEK;RHS(1)PPIEK 67.214 0.021516 18288600.0 175725.0 170613.0 174398.0 191125.0 226370.0 188246.0 186803.0 191451.0 161051.0 154515.0 True False 205471.77177304606 187550.33109796437 178556.3097280978 180416.88588560993 182014.42351064144 178374.0483718567 169107.6675033979 186425.61410910217 163406.06619644177 182527.346359933 1.1257040430964684 1.0275190805005534 0.9782441551305713 0.9884375655680581 0.9971898849157643 0.9772456123923139 0.9264785297975445 1.0213571710042944 0.8952415594440013 1.0 17.477753100086005 -1.522878745581813 0.8153532343817484 0.9686994643948145 45.133193262632076 0.6491804618554982 0.034605583736071754 318.43874041155425 1.034391397384124 0.011423862184113774 26013.69537727029 0.02999999997917482 1.522878745581813 44.16449379823726 RHS(ph)PPIEK ddPTM_PC-9_Lapatinib_30min_R1 1 RHSPPIEK 8 1 Q8IZD4;Q8IZD4-2;F5GZK9 Q8IZD4 DCP1B mRNA-decapping enzyme 1B 1 RHS(1)PPIEK 65.695 0.023417 12244000.0 113940.0 98531.0 111170.0 89369.0 102130.0 99300.0 94615.0 96813.0 112560.0 82994.0 True False 112315.194705963 98302.85752322641 102030.03172861 95941.49438624471 96122.9141953056 95053.17047960589 99513.70174524958 101311.2854132327 99882.30749065291 97339.40231744628 1.1538512876797538 1.0098978952288826 1.0481883933894158 0.985638827669779 0.9875026136058096 0.9765127812231222 1.022337299963199 1.0408044738433178 1.026124109175374 1.0 16.570736295769485 RHS(ph)SETFSSTPSATR ddPTM_PC-9_AZD4547_30min_R2 2 RHSSETFSSTPSATR 15 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 RHS(0.846)S(0.124)ET(0.025)FS(0.002)S(0.001)TPSATR;RHS(0.971)S(0.028)ET(0.001)FSSTPSATR 81.632 0.021021 3045200.0 4695.3 3476.3 4501.5 10799.7 11638.0 11330.2 4658.6 8587.5 5869.5 8306.2 True False 6188.307731692986 4599.945992248368 4441.807168772151 8309.996018701719 10022.264586502788 10621.720802888243 5073.206375095972 7260.499196118562 6179.749787178258 8015.402466210518 0.7720520283017882 0.5738883370660124 0.5541589692466343 1.0367534323738679 1.2503757146010241 1.3251637516225592 0.6329322072699936 0.9058184198143135 0.770984340864906 1.0 12.968559246892 -5.7644288257275935 24.976133294320217 0.9950156019320427 0.6274185979840343 0.401912928327142 0.19858886871086076 80.69737826578594 674217.0182083872 0.060789654265205044 0.09475417374795846 1.7201692277610847e-06 5.7644288257275935 -0.3675970039480084 RHS(ph)SETFSSTPSATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RHSSETFSSTPSATR 15 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 RHS(0.889)S(0.099)ET(0.007)FS(0.002)S(0.001)T(0.002)PS(0.001)ATR 59.251999999999995 0.025457 5988800.0 1895.3 4109.5 7904.7 6652.5 7566.6 5619.9 6579.3 4849.2 6713.1 5672.0 True False 2216.136856118671 4517.464001260656 8093.178026741684 6279.781992696003 6083.979047292582 5325.182550731471 5956.06107399296 4721.9136381521 6811.266387562545 6700.288700472705 0.3307524429450812 0.674219306541515 1.2078849716088667 0.9372405090922372 0.9080174480934468 0.7947691194792516 0.8889260359143569 0.7047328629017089 1.0165631201954044 1.0 12.710007544078314 -4.924290130116679 3.844410909795037 0.9165710445605993 0.34332600770256577 0.6747473533267165 0.1294678438241729 0.13879042703815828 3.7971087737465172 0.03365314076006326 0.1746794087134406 1.1904464654200087e-05 4.924290130116679 -0.5732450368580335 RHS(ph)SSDLAR ddPTM_PC-9_AZD4547_30min_R2 1 RHSSSDLAR 9 1 G5E9Y3;Q8WWN8;Q8WWN8-2 G5E9Y3 ARAP3 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 1 RHS(0.756)S(0.214)S(0.029)DLAR 96.604 0.0023156999999999995 1179700.0 0.0 0.0 1310.2 2666.7 2855.1 2190.7 786.1 1932.5 1259.8 2069.9 True False 0.0 0.0 1292.825891930528 2051.9335151042956 2458.7186476133447 2053.715182687621 856.0613771225143 1633.8765294322122 1326.3904560673252 1997.433431028527 0.0 0.0 0.6472435435632119 1.0272850565276186 1.2309389686880783 1.0281770349813928 0.42858067949814355 0.8179879759952198 0.6640473897467184 1.0 10.963931707552332 -5.356556360676811 3.364852169651774 0.8773615960236409 6.1519086193198296e-18 0.733103364782467 0.21023034320985598 0.13440018496031403 2.849440882349422 0.063106741606647 0.15326129269169683 4.399908442070672e-06 5.356556360676811 -0.8773615960236409 down RHS(ph)SSDLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RHSSSDLAR 9 1 G5E9Y3;Q8WWN8;Q8WWN8-2 G5E9Y3 ARAP3 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 1 RHS(0.724)S(0.233)S(0.043)DLAR 59.265 0.034349 697230.0 2549.4 3823.6 2273.4 2395.9 2866.2 2674.9 2580.3 2498.8 2388.4 2611.2 True False 2980.963067054788 4203.181738707929 2327.606477917511 2261.6654906126037 2304.588685188858 2534.6235351076725 2335.8753042457442 2433.2091476974488 2423.3258315911257 3084.589889752174 0.9664049917813511 1.3626387587769817 0.7545918780485008 0.7332143239289141 0.7471296890537421 0.8217051944339067 0.7572725670942974 0.7888274404909434 0.7856233464429282 1.0 11.590862973922931 -5.277869773486349 24.97376485680779 0.7861872163100444 1.1645218755937017 0.6181046033389195 0.11473939887723046 384.9943435742443 585181.0280991808 0.02729421064251411 0.05708348175086032 5.273879790242311e-06 5.277869773486349 0.3783346592836573 RHS(ph)VTLPSSK ddPTM_PC-9_AZD4547_30min_R2 1 RHSVTLPSSK 10 1 G3V2D5;G3V515;G3V2P5;Q07352 G3V2D5 ZFP36L1 Zinc finger protein 36, C3H1 type-like 1 1 RHS(0.996)VT(0.004)LPSSK 81.565 0.023666 4866700.0 14547.0 10559.0 18008.0 28549.0 23208.0 19290.0 15990.0 18308.0 21873.0 22004.0 True False 19172.643403603146 13971.99025750095 17769.202153781825 21967.46912765309 19985.96979924014 18083.793250579354 17413.079023265484 15478.919275987033 23029.16212538547 21233.646657496356 0.902936914834382 0.6580118094113739 0.8368417559359057 1.0345594179838 0.9412405754705477 0.8516574445395618 0.820070113445066 0.7289807316503656 1.0845599202459753 1.0 14.374064539907094 -14.522878736733048 0.03449130997867717 1.7033085726001478 0.42347476926108873 0.14115642771831094 0.11810242314375997 2552.236011415455 6.581185653927899 203.4735090086169 71.86671817005592 3.000000059042583e-15 14.522878736733048 -1.279833803339059 RHS(ph)VTLPSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RHSVTLPSSK 10 1 G3V2D5;G3V515;G3V2P5;Q07352 G3V2D5 ZFP36L1 Zinc finger protein 36, C3H1 type-like 1 1 RHS(0.969)VT(0.031)LPSSK;RHS(0.984)VT(0.016)LPSSK 84.734 0.0056637 19118300.0 93530.0 103491.0 116598.0 133543.0 154205.0 146570.0 125327.0 171003.0 125829.0 105465.0 True False 109362.78169829548 113764.9025318084 119378.13852037724 126061.01866224725 123989.63721985479 138883.61117826143 113455.11927109504 166514.35244265533 127669.01107991948 124584.9696395193 0.8778168186317459 0.9131511037084309 0.958206586763975 1.011847729521457 0.9952214747783213 1.1147701972406028 0.9106645817659389 1.336552498463151 1.0247545225505428 1.0 16.926770501590816 -5.807595578605278 0.6253101254153554 1.1009592239446935 0.8527682058686262 0.303529564674075 0.10469179938916158 1.4599631451861734 0.96556992845276 0.0613902783967294 0.22273534973888193 1.5574152444803057e-06 5.807595578605278 -0.24819101807606725 RHS(ph)VTLPSSK ddPTM_PC-9_Lapatinib_30min_R1 3 RHSVTLPSSK 10 1 G3V2D5;G3V515;G3V2P5;Q07352 G3V2D5 ZFP36L1 Zinc finger protein 36, C3H1 type-like 1 1 RHS(0.98)VT(0.02)LPSSK;RHS(0.776)VT(0.223)LPSSK;RHS(0.933)VT(0.067)LPSSK 79.639 0.008595700000000001 103739000.0 613720.0 458293.0 612324.0 510668.0 595789.0 541020.0 522439.0 503834.0 694419.0 619592.0 True False 604968.2402575361 457231.8507159377 561981.0843589948 548224.228258508 560745.8623862414 517881.8357792189 549488.3351063402 527243.9669764471 616206.2196637505 726687.6516455568 0.8325010599638074 0.6291999728914526 0.7733461317065315 0.7544152250517467 0.771646334042492 0.7126608448712387 0.7561547713959975 0.7255441396073307 0.8479657226435247 1.0 19.47097586574445 -8.574467769052896 2.670943555827799 0.999696113829012 0.7421230153662007 0.7189519874142765 0.0495481784422483 0.14988319868016528 2.606321013595483 0.04428997498825235 0.01192281246331311 2.6639877959486705e-09 8.574467769052896 -0.2575730984628113 RHS(ph)VVAGGGGGEGR ddPTM_PC-9_AZD4547_30min_R2 3 RHSVVAGGGGGEGR 14 1 Q6PKG0;Q6PKG0-3 Q6PKG0 LARP1 La-related protein 1 1 RHS(1)VVAGGGGGEGR;RHS(1)VVAGGGGGEGR;RHS(1)VVAGGGGGEGR 70.335 0.012669 47735400.0 8160.8099999999995 6471.719999999999 8591.7 11143.2 11077.4 6622.52 5830.96 11265.7 9549.5 11380.9 True False 10755.777824607037 8563.576928617673 8477.76844428295 8574.30740072381 9539.494219842418 6208.412777492318 6349.904143933715 9524.844925032065 10054.26707430936 10982.458155076358 0.9793597820024889 0.779750471861291 0.7719372406954559 0.7807275274489034 0.8686119341536515 0.5653026571854171 0.5781860540027313 0.8672780529220092 0.915484214220478 1.0 13.422913382091544 -7.991613366709647 24.98634732534684 0.9356218371329231 0.7565507371955316 0.3156357990565837 0.11683361318814928 235.31488644553608 701075.0514581574 0.06843764316663088 0.032794233332402827 1.0194985989657318e-08 7.991613366709647 -0.17907109993739156 RHS(ph)VVAGGGGGEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RHSVVAGGGGGEGR 14 1 Q6PKG0;Q6PKG0-3 Q6PKG0 LARP1 La-related protein 1 1 RHS(1)VVAGGGGGEGR 60.09 0.026187000000000002 14803000.0 4061.8 3750.0 4504.6 3221.8 3202.3 2781.7 1801.0 2920.2 1259.1 2011.5 True False 4749.3825157931815 4122.275217113382 4612.006747790631 3041.2929912165305 2574.8323029028957 2635.822755097019 1630.3962418891563 2843.547844207655 1277.5119555168242 2376.1690269747614 1.9987561751193668 1.7348409016010486 1.9409422037886104 1.2799144154692468 1.0836065421579306 1.109274098422551 0.6861448926320314 1.1966942637190843 0.5376351349648298 1.0 11.214421749464428 -6.001551939801042 1.3059099953513416 0.8972535366895598 1.9352760304602832 0.822014155804125 0.1984096617099662 0.16928139778190052 0.586191445150866 0.0679275318162558 0.1259817381113731 9.964329038065665e-07 6.001551939801042 1.0380224937707234 RHS(ph)VVAGGGGGEGR ddPTM_PC-9_Lapatinib_30min_R1 4 RHSVVAGGGGGEGR 14 1 Q6PKG0;Q6PKG0-3 Q6PKG0 LARP1 La-related protein 1 1 RHS(1)VVAGGGGGEGR;RHS(1)VVAGGGGGEGR;RHS(1)VVAGGGGGEGR;RHS(1)VVAGGGGGEGR 66.068 0.017181000000000002 50702200.0 10442.64 12342.380000000001 11396.010000000002 13463.39 9545.119999999999 6012.2 7455.0599999999995 8480.49 12579.5 6899.48 True False 10293.726038654366 12313.801977423569 10459.074047670738 14453.532613152436 8983.694808027945 5755.072221122722 7841.046528911266 8874.524524950837 11162.664241992428 8092.04592502078 1.2720795376143312 1.5217167687282926 1.2925129373439486 1.7861407049682954 1.1101883122351257 0.7112011318828425 0.9689819609978463 1.096697251496141 1.3794613062534942 1.0 12.982288792350142 -6.49761101101055 23.157475590891906 1.0197830140948438 1.4579944841139088 0.5164978888665328 0.2017840796273507 243.6829397003358 223331.52621367486 0.06392708847381368 0.07210456148986126 3.1797208086998617e-07 6.49761101101055 0.4382114700190649 RHS(ph)WGPGK ddPTM_PC-9_Lapatinib_30min_R1 2 RHSWGPGK 8 1 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36;H0YMW2;H0YLH1 Q12802-2 AKAP13 A-kinase anchor protein 13 1 RHS(1)WGPGK;RHS(1)WGPGK 83.883 0.006612699999999999 25720000.0 82626.0 57112.0 69776.0 59297.0 58742.0 56994.0 51258.0 65972.0 73219.0 47333.0 True False 81447.73808824728 56979.760672950804 64039.286623149 63657.8991889933 55286.91105121551 54556.499479503094 53911.88843267978 69037.29996262692 64972.30518974868 55514.445982741956 1.4671449322139922 1.0263951961380355 1.1535607622393853 1.1466907047722847 0.9959013383363822 0.9827441941231537 0.9711326030244385 1.2435916226938277 1.1703675329831615 1.0 15.7605756183236 -4.756581212619643 24.99599100676804 1.0801491483389385 1.467145522935513 0.6244317363075856 0.0908037865364682 107.46652882878539 552866.8633739202 0.02422644919023948 0.1935009058699244 1.751534868370613e-05 4.756581212619643 0.38699637459657454 RHS(ph)YAGEQPETVPYLLLNR ddPTM_PC-9_AZD4547_30min_R2 5 RHSYAGEQPETVPYLLLNR 19 1 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 RHS(0.705)Y(0.295)AGEQPETVPYLLLNR;RHS(0.957)Y(0.043)AGEQPETVPYLLLNR;RHS(0.961)Y(0.039)AGEQPETVPYLLLNR;RHS(0.584)Y(0.398)AGEQPET(0.018)VPYLLLNR;RHS(0.553)Y(0.445)AGEQPET(0.002)VPYLLLNR 98.376 0.00025485 26356500.0 60030.9 52789.0 81194.59999999999 131338.9 100447.5 86814.6 61731.5 93136.8 71815.0 83229.1 True False 79119.4774797113 69852.01190484125 80117.9065523908 101060.74577077717 86502.0984750594 81386.06933808952 67225.48391023853 78744.64763074895 75610.99428677182 80315.27454196628 0.9851112124178801 0.8697226312579212 0.9975425846365955 1.2583004459254008 1.0770317224012027 1.013332392900727 0.8370199105166716 0.9804442315590087 0.9414273277153976 1.0 16.293386768417037 -7.02024932749943 23.623879598475867 0.9362479029903573 1.0389527908291947 0.17912629922912915 0.0993512117391808 723.5422490469577 844117.935821233 0.041673185108811774 0.032742928446678594 9.544444842416418e-08 7.02024932749943 0.10270488783883736 RHS(ph)YAGEQPETVPYLLLNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RHSYAGEQPETVPYLLLNR 19 1 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 RHS(0.973)Y(0.026)AGEQPETVPYLLLNR;RHS(0.955)Y(0.045)AGEQPETVPYLLLNR;RHS(0.732)Y(0.196)AGEQPET(0.071)VPY(0.001)LLLNR;RHS(0.941)Y(0.059)AGEQPETVPYLLLNR 104.16 0.00012127 15323300.0 34978.7 31179.5 42017.3 46244.9 52726.4 41374.8 44499.200000000004 48510.799999999996 47040.700000000004 32166.8 True False 40899.90304918385 34274.794701863146 43019.15178349759 43653.94818098867 42395.04041962939 39205.032651827336 40283.91362969125 47237.44290144127 47728.58124523893 37998.38620775128 1.0763589491819179 0.9020065882395668 1.1321310212569533 1.1488368990808275 1.1157063404703549 1.0317552023783028 1.0601480128509706 1.2431433967531313 1.2560686389229547 1.0 15.213650528118485 -5.286128561304079 24.168726043203478 1.127248531086733 0.9891827724617271 0.27528441729968856 0.08698412555330287 569.0304121574104 557034.3352361203 0.023543438622534114 0.04905094727556377 5.1745363092283055e-06 5.286128561304079 -0.13806575862500592 RHS(ph)YAGEQPETVPYLLLNR ddPTM_PC-9_Lapatinib_30min_R1 3 RHSYAGEQPETVPYLLLNR 19 1 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 RHS(0.546)Y(0.444)AGEQPET(0.01)VPYLLLNR;RHS(0.835)Y(0.165)AGEQPETVPYLLLNR;RHS(0.793)Y(0.207)AGEQPETVPYLLLNR 90.87200000000001 0.00044529 15014900.0 32458.3 26814.899999999998 32131.9 29260.7 28760.0 29930.800000000003 25523.1 27462.6 31914.0 22539.7 True False 31995.438689876788 26752.811746552554 29490.13921472087 31412.629488833772 27068.39334433553 28650.729456102603 26844.561232512577 28738.61265315032 28319.509250681396 26435.6571127376 1.2103137271537803 1.0119972290630952 1.1155440202964169 1.1882673978888194 1.0239349537974245 1.083791083154037 1.015467900723298 1.0871155020127372 1.071261785924591 1.0 14.69019756787244 -6.283037162060539 24.978866373986577 1.0515544077567274 1.1218506090827132 0.3442764480390649 0.05635561961613766 1086.952717578754 1257108.9235960834 0.017113734061254944 0.019419468737063728 5.211501150036778e-07 6.283037162060539 0.0702962013259858 RHSS(ph)ETFSSTPSATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RHSSETFSSTPSATR 15 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 RHS(0.087)S(0.907)ET(0.005)FSSTPSATR 59.57899999999999 0.024872 2008400.0 1337.5 1557.7 3318.3 3481.0 4299.9 4537.5 4358.5 1378.9 4288.0 4020.3 True False 1563.912333170856 1712.338161519337 3397.4208567228297 3285.97085555427 3457.3654620904204 4299.545512187772 3945.631327192606 1342.7053360653163 4350.703887900995 4749.148565322713 0.32930372921795203 0.3605568741358128 0.7153747266468109 0.6919073619948932 0.7279969060844671 0.905329756070836 0.8308081486443231 0.2827254859680468 0.9161018713267727 1.0 12.213453172697005 -5.260500555848804 4.11730077544305 0.7399723798900721 0.3332715859776316 0.4404956449632955 0.1859585173667356 0.19295786491272912 8.027142088684739 0.0485408418409005 0.12600997885369833 5.489078530653789e-06 5.260500555848804 -0.4067007939124405 RHSYAGEQPET(ph)VPYLLLNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RHSYAGEQPETVPYLLLNR 19 1 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 RHS(0.296)Y(0.238)AGEQPET(0.466)VPYLLLNR 63.461999999999996 0.034019 3739500.0 7011.7 7051.8 5231.5 7474.0 9598.6 11528.0 7059.8 12476.0 7601.5 7076.2 True False 8198.642322612406 7751.856100277374 5356.238800574232 7055.256011034935 7717.823234126639 10923.451386115845 6391.044635474217 12148.51821941467 7712.657556874867 8359.05904483162 0.9808092368580171 0.9273598928662099 0.640770542694752 0.8440251436430728 0.9232885176111474 1.306780024824658 0.7645650785809176 1.4533356152001415 0.9226705440779939 1.0 13.029124836088123 -6.5375146897622916 23.929208545022373 1.099445826330265 0.8446461247353234 0.25347211232597533 0.19709316062502152 184.7562206778967 302066.1154700119 0.061828072967042805 0.061857736828896726 2.9005830864710527e-07 6.5375146897622916 -0.2547997015949417 RHT(ph)IASGVDCGLLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RHTIASGVDCGLLK 14 1 Q86UD0 Q86UD0 SAPCD2 Suppressor APC domain-containing protein 2 1 RHT(0.992)IAS(0.008)GVDCGLLK 62.035 0.042269 2791300.0 15044.0 15560.0 14025.0 15219.0 15296.0 13326.0 13701.0 16420.0 15009.0 9192.2 True False 17590.652067455958 17104.693967542466 14359.409190108687 14366.328770663726 12298.858603254741 12627.161100917738 12403.142093349981 15988.992398428092 15228.47823076168 10858.673094584836 1.619963315428321 1.5752103243694193 1.3223907806258253 1.3230280205993252 1.1326299720163893 1.1628640986728698 1.1422336767404264 1.4724628192740898 1.4024253330138508 1.0 13.406560199374946 -5.302063606569467 1.8130739501289026 1.2400183027149827 1.6406745550387896 0.5482355926292208 0.13080656994233572 0.3396516240656289 1.9828865274456957 0.03979878560635766 0.16034909323061516 4.988114264185023e-06 5.302063606569467 0.40065625232380686 RHT(ph)IASGVDCGLLK ddPTM_PC-9_Lapatinib_30min_R1 1 RHTIASGVDCGLLK 14 1 Q86UD0 Q86UD0 SAPCD2 Suppressor APC domain-containing protein 2 1 RHT(0.993)IAS(0.007)GVDCGLLK 61.167 0.045047000000000004 3167000.0 12788.0 15236.0 19782.0 15632.0 16842.0 15429.0 12016.0 10810.0 13794.0 12089.0 True False 12605.640774968017 15200.721978097043 18155.600320728263 16781.629426823318 15851.386672646004 14769.137636755686 12638.129685260457 11312.272063845201 12240.374462740456 14178.567542420038 0.8890630691185077 1.0720915164821043 1.2804960914711285 1.1835913167261312 1.117982237995563 1.0416523102611568 0.8913544790366986 0.7978430846417077 0.8633012062832994 1.0 13.791424164324521 -7.149614261287217 2.6473748334651193 0.8674166176324718 1.1192304929760823 0.497418842544717 0.10395271487073429 0.23507209161475295 3.202805156634846 0.04809848698575125 0.03498844583011802 7.08574858475859e-08 7.149614261287217 0.25181387534361055 RHT(ph)VEDAVVSQGPEAAGPLSTPQEVSASR ddPTM_PC-9_AZD4547_30min_R2 3 RHTVEDAVVSQGPEAAGPLSTPQEVSASR 29 1 Q96NW4 Q96NW4 ANKRD27 Ankyrin repeat domain-containing protein 27 1 RHT(0.996)VEDAVVS(0.004)QGPEAAGPLSTPQEVSASR;RHT(0.994)VEDAVVS(0.006)QGPEAAGPLSTPQEVSASR;RHT(1)VEDAVVSQGPEAAGPLSTPQEVSASR 121.09 1.4708e-07 8971500.0 2494.4 3322.2999999999997 6598.61 10346.18 9001.36 6736.8 5810.52 7536.0 3344.1 3911.7299999999996 True False 3287.567313256869 4396.168503882508 6511.108119944821 7961.028047887567 7751.676538783529 6315.546831026595 6327.645023531248 6371.484360052345 3520.8622988845427 3774.7815233379474 0.8709291631664429 1.1646153497103808 1.7248966806924515 2.1090036598589217 2.0535430966952783 1.6730893674190475 1.6762943721139827 1.6879081135318785 0.9327327362170433 1.0 11.882177431267182 -8.262032632627403 24.96110025201454 0.966366276502407 1.6427427416482578 0.3570663371543652 0.34979371957479843 61.997189654996006 2608194.973600941 0.3116945081740306 0.09903057404750007 5.469748619861304e-09 8.262032632627403 0.6763764651458508 RHT(ph)VEDAVVSQGPEAAGPLSTPQEVSASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RHTVEDAVVSQGPEAAGPLSTPQEVSASR 29 1 Q96NW4 Q96NW4 ANKRD27 Ankyrin repeat domain-containing protein 27 1 RHT(1)VEDAVVSQGPEAAGPLSTPQEVSASR;RHT(0.993)VEDAVVS(0.007)QGPEAAGPLSTPQEVSASR 98.39 8.861200000000001e-11 5690900.0 3911.4 5636.4 6990.1 7276.799999999999 8822.2 3782.3 5993.0 7837.5 4837.95 6277.9 True False 4573.522766328588 6195.944542330099 7156.770494101877 6869.104487703905 7093.553240692604 3583.949529641391 5425.29965443737 7631.77392951767 4908.695866247814 7416.033574170943 0.6167073976387537 0.8354795700911802 0.9650401960190628 0.9262504570675193 0.9565157937524049 0.4832704024053788 0.7315635238401517 1.0290910704744005 0.6619031342231442 1.0 12.856432060068395 -10.762904260670132 4.267947715322176 1.0000969608829173 0.8101375191403988 0.1110277196756203 0.16729947991139094 247274313.3706428 49.851256832265925 263327.240050287 0.04151596936660308 1.7262183913606418e-11 10.762904260670132 -0.18995944174251855 RHT(ph)VEDAVVSQGPEAAGPLSTPQEVSASR ddPTM_PC-9_Lapatinib_30min_R1 2 RHTVEDAVVSQGPEAAGPLSTPQEVSASR 29 1 Q96NW4 Q96NW4 ANKRD27 Ankyrin repeat domain-containing protein 27 1 RHT(1)VEDAVVSQGPEAAGPLSTPQEVSASR;RHT(0.999)VEDAVVS(0.001)QGPEAAGPLSTPQEVSASR 102.31 4.5404e-11 10734300.0 4025.8 6305.799999999999 9656.0 7427.299999999999 6264.5 8391.7 5785.0 5797.9 7101.4 5927.5 True False 3968.3913537586977 6291.199307527194 8862.120953237902 7973.5284187464695 5896.034426480873 8032.806553008145 6084.5189937776095 6067.291600274565 6301.565550942804 6952.060477102721 0.570822329125153 0.9049402444423295 1.2747473907090061 1.14693024391949 0.8480988400345522 1.1554569439470448 0.8752108837110317 0.8727328567203598 0.906431348187723 1.0 12.763224917107364 RHT(ph)VGVADPR ddPTM_PC-9_AZD4547_30min_R2 2 RHTVGVADPR 10 1 H0Y4E8;Q9Y2K2-7;Q9Y2K2;Q9Y2K2-8;H7C3X8 H0Y4E8 SIK3 Serine/threonine-protein kinase SIK3 1 RHT(1)VGVADPR;RHT(1)VGVADPR 87.21600000000001 0.009142 32288000.0 124017.0 107395.0 158531.0 223816.0 162070.0 134052.0 169120.0 161074.0 154049.0 166947.0 True False 163451.82628615224 142108.33352631048 156428.77535768467 172218.67912272975 139569.37803183615 125669.7072486606 184171.3523711482 136183.71441229686 162191.71564273318 161102.23634471197 1.014584465087206 0.8821003156172205 0.970990713145487 1.0690024113273748 0.8663404133832024 0.7800618420948792 1.14319550460538 0.8453247918973843 1.006762657817425 1.0 17.29761699542749 RHT(ph)VGVADPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RHTVGVADPR 10 1 H0Y4E8;Q9Y2K2-7;Q9Y2K2;Q9Y2K2-8;H7C3X8 H0Y4E8 SIK3 Serine/threonine-protein kinase SIK3 1 RHT(1)VGVADPR;RHT(1)VGVADPR 78.548 0.017187 31054000.0 157615.0 121794.0 145406.0 162537.0 151573.0 120901.0 119180.0 149802.0 118226.0 96814.0 True False 184296.10646185 133884.9034114951 148873.0304953255 153430.57884206358 121873.35872588455 114560.73872595344 107890.40761152109 145869.85622833908 119954.83158838227 114365.61182079795 1.611464351282689 1.1706744823022708 1.3017289736411153 1.3415796619221292 1.0656468914523944 1.0017061676324632 0.9433815453248044 1.2754695568533823 1.048871506728283 1.0 16.803293793042393 -1.5228787452804242 0.4195589014401679 1.0547556911332405 9.967815442473281 0.6063873505929704 0.12335448096289317 59.38027528661894 0.7614959793015328 0.0878500262330111 444.05476611808945 0.029999999999994014 1.5228787452804242 8.91305975134004 RHVTLPS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 RHVTLPSSPR 10 1 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;A0A0A0MSW0;X6RE05 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 RHVT(0.007)LPS(0.705)S(0.288)PR 59.155 0.033826999999999996 5483200.0 4139.5 3645.8 11448.0 16664.0 10557.0 8869.5 5458.8 10182.0 7067.6 9783.8 True False 5455.774893051158 4824.2335524952105 11296.192040009675 12822.372256233537 9091.34277708455 8314.88876288303 5944.622624903164 8608.605859083455 7441.178907208634 9441.272139956951 0.577864382275505 0.5109728308834881 1.1964692758089677 1.358119124854715 0.9629362062987842 0.8806958045084954 0.6296421220340196 0.9118057112929177 0.7881542653257915 1.0 13.204765549583376 -10.115500549536266 15.668539061400317 0.999999807894758 0.8794300072214519 0.022301779905949726 0.25201349338820966 0.0 0.0 0.2692894227251156 0.06531227845630921 7.664775702965067e-11 10.115500549536266 -0.12056980067330603 RHVTLPS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RHVTLPSSPR 10 1 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;A0A0A0MSW0;X6RE05 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 RHVT(0.031)LPS(0.738)S(0.231)PR;RHVT(0.001)LPS(0.499)S(0.499)PR 81.95 0.022764 2531400.0 11074.8 12663.9 23537.5 16550.1 22003.9 21340.0 18315.5 15228.5 16468.2 13490.6 True False 12949.54490272942 13921.088299200583 24098.723266465826 15622.851553148153 17692.3937513178 20220.89283307702 16580.523247263096 14828.768010929498 16709.016270226486 15936.338988469168 0.8125796591111133 0.8735436858661998 1.5121869134374337 0.9803287671310306 1.1101918554894719 1.2688543364763996 1.0404223491518367 0.9305002875289576 1.0484852438390269 1.0 13.96003262055841 -10.058982866845906 7.476948101032359 0.9999999999991689 1.0719796320345947 0.008413179458159004 0.19251794173371797 0.0 0.0 0.18967521287667027 0.04600299596619371 8.73005808263882e-11 10.058982866845906 0.07197963203542579 RHVTLPS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 RHVTLPSSPR 10 1 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;A0A0A0MSW0;X6RE05 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 RHVT(0.001)LPS(0.5)S(0.5)PR 53.597 0.045202 3008400.0 12247.0 7457.4 9996.1 7019.1 7805.3 10203.0 6268.9 5794.9 9947.2 7238.2 True False 12072.355534175256 7440.1328484812875 9174.25924406186 7535.308029031192 7346.207599810227 9766.641474354668 6593.472968036719 6064.152209322528 8826.841587340285 8489.313225704756 1.422065037913953 0.8764116307963924 1.0806833250401409 0.8876228063084142 0.8653476912085981 1.1504630839609375 0.7766791956824457 0.7143277728239437 1.0397592069772532 1.0 13.051432131026228 -4.757910580964095 24.981626081593756 0.9265314818832496 1.422065741332327 0.5628575902559514 0.12937611878011973 74.9254912164514 530342.2025408538 0.032302600773294846 0.23079266824082137 1.7461816458739857e-05 4.757910580964095 0.49553425944907736 RHVTLPSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 RHVTLPSSPR 10 1 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;A0A0A0MSW0;X6RE05 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 RHVT(0.027)LPS(0.33)S(0.642)PR 60.06399999999999 0.032014 3921100.0 3671.7 4603.6 7640.5 12960.0 10298.0 8286.2 5667.6 11409.0 5772.6 9988.1 True False 4839.224223895629 6091.6236716953645 7539.181977785987 9972.272230004006 8868.300456419127 7768.062604092836 6172.005420403967 9646.00120273848 6077.727851003527 9638.419659141036 0.502076522400239 0.6320147790948378 0.7822010500067673 1.0346376877817667 0.9200990172707897 0.8059477464986325 0.6403545019489231 1.0007865961294031 0.6305730675712419 1.0 13.23458090240122 -5.169513688027364 2.505391112503953 0.8548659965107913 0.5188883378772039 0.4366010992913545 0.13449184613966741 0.2936695920626035 3.400013086939192 0.03608373657321792 0.14307835527261917 6.768404600289867e-06 5.169513688027364 -0.3359776586335874 RHVTLPSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RHVTLPSSPR 10 1 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;A0A0A0MSW0;X6RE05 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 RHVTLPS(0.133)S(0.866)PR 74.84100000000001 0.011609999999999999 3326400.0 5365.5 5840.4 9929.9 10231.0 11352.0 10488.0 8040.2 9130.8 8470.2 5002.9 True False 6273.773176544467 6420.196314141065 10166.666475355458 9657.790239349528 9127.657091013858 9937.990816931208 7278.57404999289 8891.126174882289 8594.060650955926 5909.8861670653905 1.0615725919573453 1.0863485577640277 1.72028126903903 1.634175340494789 1.5444725723958033 1.6815875189464116 1.2315929349967725 1.5044496498817101 1.4541837876419517 1.0 12.528914626944445 -10.683778522894249 4.604853047072139 0.9999390116150385 1.4458500150876017 0.2524263669630983 0.22414223652604282 171268252.20159823 13.07827361850458 110755.56443643213 0.05793588445357615 2.071197327766553e-11 10.683778522894249 0.4459110034725632 RHYS(ph)VEER ddPTM_PC-9_AZD4547_30min_R2 1 RHYSVEER 8 1 Q8IWA4-3;Q8IWA4;H7C5H5 Q8IWA4-3 MFN1 Mitofusin-1 1 RHY(0.366)S(0.634)VEER 74.255 0.012856 8079000.0 1086.5 989.04 1207.8 4676.3 3544.9 2213.0 641.4 1079.0 2537.4 3265.4 True False 1431.9843993960828 1308.7278382686557 1191.7837828374993 3598.251283114794 3052.75182442806 2074.6207601623696 698.4833574435572 912.2653429533538 2671.5217837952327 3151.0793399104045 0.45444250839993094 0.41532684426342215 0.3782144637689083 1.1419107216821471 0.9687956078296841 0.6583841713808951 0.2216647954866847 0.28950884587351977 0.847811652965613 1.0 11.621630364582204 -8.511383781827275 21.581114145913205 1.0000000867663363 0.5783236856429173 0.21870767954742243 0.2773240241287325 161.21452919790727 302668.2275876314 0.30023061439998655 0.0775192113193305 3.0804645704095212e-09 8.511383781827275 -0.4216764011234191 RHYTLDAS(ph)LPLR ddPTM_PC-9_Lapatinib_30min_R1 1 RHYTLDASLPLR 12 1 Q8IXX5-2;Q8IXX5;Q1AE95 Q8IXX5-2 TMEM183A;TMEM183B Transmembrane protein 183A;Transmembrane protein 183B 1 RHYTLDAS(1)LPLR 76.655 0.008443299999999999 5115400.0 23270.0 28193.0 29066.0 24772.0 25345.0 29371.0 23042.0 26276.0 26048.0 17080.0 True False 22938.165532804633 28127.72084067275 26676.30567800463 26593.815516969502 23854.256930187188 28114.87079714507 24235.00201462812 27496.878885254057 23114.19994239985 20032.255242330564 1.1450615647275466 1.4041215280262351 1.3316676208095826 1.3275497538975827 1.1907923816675556 1.4034800603845625 1.2097989827633908 1.3726302182467127 1.153849112982385 1.0 14.290037229245845 -8.525246048489597 4.10401934393131 1.0003947332007375 1.300084025394982 0.5517079912179377 0.08541853132568122 0.12151601236060158 6.29656560566482 0.07609955395280357 0.019925594164119268 2.983691736634863e-09 8.525246048489597 0.29968929219424445 RIDFIPVS(ph)PAPSPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RIDFIPVSPAPSPTR 15 1 Q96E09 Q96E09 FAM122A Protein FAM122A 1 RIDFIPVS(0.998)PAPS(0.001)PT(0.001)R 72.793 0.0086712 1678800.0 6488.4 7075.0 8027.9 7583.9 10320.0 8873.9 8011.3 9282.0 6819.7 7016.6 True False 7586.757968258528 7777.359242953919 8219.315581980285 7158.998670335538 8297.870082739862 8408.537062391857 7252.4116672107675 9038.357335091932 6919.425210895159 8288.654036624957 0.9153184503461032 0.9383138937381404 0.9916345338654156 0.8637106385068278 1.0011118869329305 1.0144635094235053 0.8749806223259698 1.0904493413712615 0.8348068552892174 1.0 13.01692213157734 RIDFIPVSPAPS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 2 RIDFIPVSPAPSPTR 15 1 Q96E09 Q96E09 FAM122A Protein FAM122A 1 RIDFIPVSPAPS(0.981)PT(0.019)R;RIDFIPVSPAPS(0.96)PT(0.039)R 176.68 2.358e-05 23752000.0 33580.0 28451.0 36981.0 50830.0 49214.0 37725.0 33830.0 52962.0 39698.0 39822.0 True False 44257.741492609755 37647.22936037119 36490.607777043835 39111.92881567158 42381.48559547589 35366.04978631967 36840.80446260609 44777.9398456863 41796.355234926734 38427.843900873435 1.151710244446054 0.9796862258908962 0.9495876966496793 1.0178018032071425 1.1028848171862329 0.920323551785736 0.9587007940814687 1.165247260845372 1.0876580883055147 1.0 15.229864411875742 -7.752875861028774 24.999862102399042 1.0948395138326878 1.0081680611613162 0.15568899449339824 0.07620915566639373 286.7314095836087 837073.8404434473 0.03654390015279758 0.02066775241913121 1.7665426980523947e-08 7.752875861028774 -0.08667145267137166 RIDFIPVSPAPS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RIDFIPVSPAPSPTR 15 1 Q96E09 Q96E09 FAM122A Protein FAM122A 1 RIDFIPVSPAPS(0.957)PT(0.043)R;RIDFIPVSPAPS(0.931)PT(0.069)R 140.8 3.4148e-05 9725000.0 42271.0 37123.0 47435.0 54653.0 66980.0 57511.0 69031.0 67272.0 58061.0 53787.0 True False 49426.645409693614 40808.32610264003 48566.0302982393 51590.96959741667 53855.749819953126 54495.02191767072 62491.88393883976 65506.18128057583 58910.03228437961 63538.15732234224 0.7779049234768015 0.6422648660648268 0.7643600687356066 0.8119683001772461 0.8476127116298281 0.8576739429380392 0.9835331487787013 1.0309738909841122 0.9271599109416536 1.0 15.955335630437068 -6.5662229392062565 0.7654005569036193 0.9995390244247815 0.7058927682662253 0.8371510225246631 0.046744305847993814 0.24774208678280832 0.32294869619450434 0.030146366833584844 0.03648900133569559 2.7150451792805863e-07 6.5662229392062565 -0.2936462561585562 RIDFTPVS(ph)PAPS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 3 RIDFTPVSPAPSPTR 15 1 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 2 RIDFT(0.001)PVS(0.996)PAPS(0.813)PT(0.19)R;RIDFT(0.001)PVS(0.998)PAPS(0.597)PT(0.404)R;RIDFTPVS(1)PAPS(0.975)PT(0.026)R 89.859 0.0033215000000000002 25727000.0 67006.0 72739.0 102664.0 116026.0 113665.0 100987.0 80699.0 108555.0 77787.0 88290.0 True False 88312.51418861854 96250.45926132801 101302.60828053417 89277.99828383053 97884.57675071665 94672.26692567414 87881.054665322 91780.31909573814 81898.66201469215 85198.99397338467 1.0365440960043086 1.1297135655310169 1.189011789413618 1.0478762027603294 1.1488935747444955 1.1111899625862816 1.031479957295918 1.0772465121408525 0.96126325200831 1.0 16.37854877481068 -7.761786331613121 1.1574322826280796 0.9871816598997776 1.1142610352368167 0.48722037441702415 0.048254188519101494 0.41842844082666325 1.0155964227803376 0.040554980072172495 0.015937215467927937 1.7306676203358704e-08 7.761786331613121 0.12707937533703917 RIDFTPVS(ph)PAPS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RIDFTPVSPAPSPTR 15 1 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 2 RIDFT(0.003)PVS(0.996)PAPS(0.772)PT(0.229)R;RIDFTPVS(1)PAPS(0.844)PT(0.156)R;RIDFT(0.001)PVS(0.999)PAPS(0.852)PT(0.148)R;RIDFT(0.019)PVS(0.981)PAPS(0.951)PT(0.049)R 130.95 6.2874e-05 10991800.0 68682.3 72062.8 80919.8 83645.1 98726.0 81378.9 82660.1 76575.5 79706.4 68132.3 True False 80308.85685274053 79216.7185375463 82849.23492205037 78958.73622807297 79381.34901052102 77111.2472246341 74829.93692070065 74565.47426344891 80871.95531030592 80484.14665501002 0.9978220580132277 0.9842524500769516 1.0293857655865837 0.981047069636265 0.9862979519529969 0.9580923750756329 0.9297475345232179 0.9264616370111854 1.0048184477491973 1.0 16.296417016259824 -6.522734976173344 2.101538704584201 0.9571808407605715 0.9999587489343904 0.2504646633324732 0.026967407758195085 0.38020560634270933 3.376730016919024 0.009837872905220481 0.010622415808890718 3.0009932862077524e-07 6.522734976173344 0.04277790817381888 RIDFTPVS(ph)PAPS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 2 RIDFTPVSPAPSPTR 15 1 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 2 RIDFTPVS(0.997)PAPS(0.826)PT(0.177)R;RIDFT(0.089)PVS(0.913)PAPS(0.847)PT(0.151)R 87.963 0.003771 15687500.0 93588.0 86991.0 107136.0 98480.0 95571.0 105810.0 85281.0 91694.0 107528.0 86942.0 True False 92253.4179580627 86789.57768421114 98327.6916369194 105722.54771964949 89949.7016798153 101284.75295515706 89696.4328968623 95954.43798540455 95417.06431996205 101969.8088570668 0.9047130615629203 0.851130139960014 0.9642823963193592 1.036802450692469 0.8821209207707712 0.9932817771300327 0.879637158314101 0.9410083147248601 0.9357383856010766 1.0 16.637782537813422 -5.268006509400794 24.922556199294633 0.9511237454315976 0.8779215995047691 0.28319717857965276 0.04829751352904145 578.5888359133489 2195778.348977728 0.012354788304855023 0.026735665200136795 5.3950253614815255e-06 5.268006509400794 -0.0732021459268285 RIDFTPVS(ph)PAPSPT(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 RIDFTPVSPAPSPTR 15 1 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 2 RIDFTPVS(1)PAPS(0.336)PT(0.664)R;RIDFTPVS(1)PAPS(0.332)PT(0.668)R 180.03 0.00010012 20898000.0 56874.0 58966.0 84501.0 95629.0 97613.0 80096.0 72081.0 83836.0 69735.0 76857.0 True False 74958.74894731057 78025.60635702244 83380.4615280274 73583.21150332193 84061.11987302787 75087.58445818601 78496.06936060039 70881.07255962682 73421.04973317584 74166.25982345018 1.010685305228373 1.0520364184840827 1.1242371089834011 0.9921386312116025 1.1334145752142821 1.0124224227691812 1.0583797746772878 0.9557050972821924 0.9899521683842722 1.0 16.178475395831086 -7.751253640865122 24.988313771054717 0.979621475046632 1.0563150831981132 0.3596153152683188 0.04449895046982516 196.55567171880966 482206.28972181835 0.02016919575630152 0.01147381563900836 1.7731536041050807e-08 7.751253640865122 0.07669360815148119 RIDFTPVS(ph)PAPSPT(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RIDFTPVSPAPSPTR 15 1 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 2 RIDFT(0.006)PVS(0.992)PAPS(0.014)PT(0.988)R 114.03 0.00072667 1758400.0 8642.4 6079.3 9275.4 8487.6 9198.4 10786.0 8719.2 9706.4 9509.8 7061.0 True False 10105.387624819292 6682.812727305967 9496.560713150382 8012.06728917047 7396.039551266894 10220.363172332187 7893.254254458597 9451.617284780901 9648.86283422596 8341.103405154756 1.2115168861920855 0.8011904903583891 1.1385257143894847 0.960552447319986 0.8866979813121826 1.2253010993744615 0.9463081646464914 1.1331375269775283 1.1567849438556315 1.0 13.02602252826599 -6.751812842121084 24.999982635032264 1.0915025686985704 0.9942066552812946 0.11050537724976761 0.13090041398596525 442.99992986774646 1150462.9332209507 0.04099884779700023 0.04050086087964273 1.770871945751807e-07 6.751812842121084 -0.09729591341727584 RIDFTPVS(ph)PAPSPT(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 RIDFTPVSPAPSPTR 15 1 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 2 RIDFT(0.128)PVS(0.872)PAPS(0.169)PT(0.831)R 100.27 0.007586399999999999 9218000.0 21488.0 21633.0 23628.0 20269.0 22922.0 20683.0 20294.0 17482.0 19487.0 16893.0 True False 21181.577179583423 21582.910117627554 21685.397046717597 21759.649875401858 21573.773026385905 19798.436304427876 21344.724020695372 18294.27754117869 17292.16885279276 19812.932541492402 1.0690783474493133 1.08933445730098 1.0945071862180857 1.098254881241463 1.0888732892622501 0.9992683447019179 1.077312708555136 0.9233503169137969 0.872771802789888 1.0 14.27415481101118 -7.7621946524532035 24.994760560600024 0.9235457514638733 1.073851003580607 0.7302686943364138 0.039380519950650936 9.719250619589216 321600.4106285501 0.02016555831829798 0.01058394772992039 1.729041222608067e-08 7.7621946524532035 0.15030525211673373 RIDFTPVS(ph)PAPSPTR ddPTM_PC-9_AZD4547_30min_R2 2 RIDFTPVSPAPSPTR 15 1 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 RIDFTPVS(0.946)PAPS(0.044)PT(0.01)R;RIDFT(0.158)PVS(0.607)PAPS(0.232)PT(0.004)R 92.307 0.0028696999999999998 17447400.0 31046.0 33745.0 38692.0 51077.0 43889.0 33276.0 41580.0 47578.0 29122.0 29378.0 True False 40917.982203084015 44652.411330558716 38178.9187990963 39301.986781783526 37795.769929285205 31195.24645963083 45280.539448866715 40225.91333367441 30661.32946625866 28349.485161967277 1.4433412800729875 1.5750695674171502 1.3467235324017757 1.3863386427387316 1.3332083356487456 1.1003814101527787 1.5972261644318526 1.418929236416616 1.0815480172244143 1.0 14.791034915033674 -13.542957020043827 0.10444626281083823 1.781441180976609e-11 1.6303756016944615 0.4423176335028628 0.14538491434715864 141.1240476277618 1.2280206253749506 32.379622470935615 2.381203257125903 2.8644614373240936e-14 13.542957020043827 1.630375601676647 RIDFTPVS(ph)PAPSPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RIDFTPVSPAPSPTR 15 1 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 RIDFT(0.001)PVS(0.929)PAPS(0.024)PT(0.046)R;RIDFT(0.135)PVS(0.84)PAPS(0.021)PT(0.004)R 117.07 0.00019741 13918800.0 31713.0 30385.0 32346.0 43871.0 44564.0 42745.0 45713.0 37898.0 37264.0 31157.0 True False 37081.38453969896 33401.421992530726 33117.251312888104 41413.05010170105 35832.00410535073 40503.3769517281 41382.73370654022 36903.21765625016 37808.91550343815 36805.51746132369 1.0074952642267607 0.9075112726680155 0.8997904009280314 1.12518592206234 0.9735497984236751 1.100470248632973 1.1243622304733631 1.002654498609594 1.027262163700561 1.0 15.16763443434867 -5.750027242924429 24.999990018664857 1.0525621440965867 0.9351901924341384 0.4511550765250253 0.05666441750980704 191.35810439413027 419194.4975822271 0.015283317708604404 0.026176506527983628 1.7781678635787244e-06 5.750027242924429 -0.11737195166244829 RIDFTPVS(ph)PAPSPTR ddPTM_PC-9_Lapatinib_30min_R1 1 RIDFTPVSPAPSPTR 15 1 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 RIDFTPVS(0.496)PAPS(0.252)PT(0.252)R 109.37 0.00029222 21415000.0 37079.0 22257.0 22336.0 20174.0 30960.0 27216.0 41889.0 25480.0 44415.0 24542.0 True False 36550.24666054418 22205.46528396599 20499.62029945337 21657.663258491168 29138.993669701922 26052.035123594684 44057.80745554886 26663.893819313205 39412.51498931548 28784.051999840573 1.269808943533962 0.771450290740476 0.712186744922741 0.7524188484168638 1.0123311919344544 0.9050857441384201 1.5306325688889417 0.9263426087286422 1.3692483250632599 1.0 14.812982077555136 -7.047973911112792 24.592906682946612 1.2029096158072885 0.8854028950632935 0.3136941952079205 0.21846855878638483 387.9529876719418 198875.36741996993 0.08083701340956505 0.06261786273817621 8.95418553412386e-08 7.047973911112792 -0.317506720743995 RIDFTPVSPAPS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 4 RIDFTPVSPAPSPTR 15 1 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 RIDFTPVSPAPS(0.616)PT(0.384)R;RIDFTPVS(0.005)PAPS(0.979)PT(0.016)R;RIDFTPVSPAPS(0.993)PT(0.006)R;RIDFT(0.002)PVS(0.003)PAPS(0.96)PT(0.036)R 129.06 7.435700000000001e-06 63664000.0 79475.0 59287.7 107304.0 159232.0 133945.0 106236.0 98204.0 137955.0 90370.0 131122.0 True False 104746.39681730687 78451.28959083602 105881.07884881199 122523.52250987623 115349.04880899806 99593.046125897 106943.96575364383 116637.22464052834 95146.77370598851 126531.45869043066 0.8278288885736891 0.6200141087662111 0.8367964768971684 0.9683245872446616 0.9116234808547394 0.7871010668545232 0.8451966559185159 0.9218041572245732 0.7519614069950201 1.0 16.949136591801334 -1.5229333291296339 0.03574901595077864 1.388509959584316 2.5195069245441694e-06 0.22758112133091346 0.09322615688299678 1560.2129215681591 4.276749197447395 48.595030455704666 139.10226507794073 0.029996229718205696 1.5229333291296339 -1.3885074400773914 RIDFTPVSPAPS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RIDFTPVSPAPSPTR 15 1 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 RIDFTPVS(0.165)PAPS(0.417)PT(0.417)R;RIDFTPVSPAPS(0.752)PT(0.248)R;RIDFTPVSPAPS(0.946)PT(0.053)R;RIDFTPVS(0.157)PAPS(0.421)PT(0.421)R 119.37 4.5038000000000005e-05 58308000.0 49950.3 50368.6 69691.9 79509.0 103859.0 96726.2 85729.5 103120.6 96483.1 78162.3 True False 58405.89922660502 55368.86173351924 71353.61920400262 75054.36850165605 83508.57450806975 91653.70779525649 77608.58113216887 100413.79351530701 97893.98280940774 92332.50625757355 0.6325605314305469 0.5996681339837195 0.7727898017297657 0.8128704780554977 0.9044330961309738 0.9926483262522576 0.8405336785256281 1.087523750684181 1.060233137572587 1.0 16.49455102699256 -5.656853807410242 0.5302425386237686 1.0360618814243698 0.48688669941640716 0.8526034386919179 0.06186649144389939 0.6732849619934136 0.27408130358494626 0.04349477914170948 0.2075960421384982 2.2036681389181494e-06 5.656853807410242 -0.5491751820079627 RIDFTPVSPAPS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 4 RIDFTPVSPAPSPTR 15 1 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 RIDFTPVSPAPS(0.847)PT(0.153)R;RIDFTPVSPAPS(0.96)PT(0.04)R;RIDFTPVSPAPS(0.873)PT(0.127)R;RIDFTPVSPAPS(0.975)PT(0.025)R 122.94 1.9354e-05 43862900.0 67970.5 66635.2 76608.0 73754.0 88063.0 94384.0 88535.0 95965.0 122342.0 118738.0 True False 67001.22820573677 66480.9102884545 70309.58595543168 79178.1151961317 82883.30747851942 90347.41633985024 93118.90909491802 100423.8842374564 108562.55564162626 139261.70509156014 0.48111739089856465 0.4773811310492387 0.5048737979274731 0.5685562670949247 0.5951622337528202 0.64875994646518 0.6686612736336619 0.7211162908814802 0.7795578516739389 1.0 17.08743906712131 -8.133852185232438 0.201721821795013 1.136824080021718 0.3386729635353773 0.9943931221012526 0.011439911326177641 0.19563870745504044 0.03990253260745513 0.06455678068809757 0.05618484147730291 7.3476390696691644e-09 8.133852185232438 -0.7981511164863406 down RIDFTPVSPAPSPT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 RIDFTPVSPAPSPTR 15 1 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 RIDFTPVSPAPS(0.093)PT(0.907)R 95.073 0.033301 0.0 7080.1 6562.1 10894.0 18809.0 13604.0 12489.0 9170.9 13236.0 6115.5 13085.0 True False 9331.424524771475 8683.170496140445 10749.538441986855 14472.875646153176 11715.319422133007 11708.06085570169 9987.092333612592 11190.680333021864 6438.752844959301 12626.898132764029 0.7390116263438031 0.6876724912834707 0.851320595839303 1.1461940608041528 0.9278065997645395 0.9272317502365717 0.7909379032446837 0.8862572751723169 0.5099235597895695 1.0 13.624212656197162 -10.305678388877975 10.506807004207811 0.9999679959316818 0.8416614195229492 0.08825833017149831 0.1601367999491843 0.0 0.0 0.16240274853235245 0.03938845212291252 4.946768779000633e-11 10.305678388877975 -0.1583065764087327 RIDFTPVSPAPSPT(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RIDFTPVSPAPSPTR 15 1 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309;Q7Z309-5 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 RIDFTPVSPAPS(0.086)PT(0.914)R 159.44 0.00090606 8604200.0 7744.7 7329.8 8825.0 11315.0 17569.0 18499.0 17574.0 19702.0 19014.0 13316.0 True False 9055.724745202493 8057.454103039377 9035.42146899887 10681.057233724947 14126.480570121777 17528.879874371698 15909.263495258194 19184.843375994536 19292.04377904606 15730.085390601997 0.575694570012498 0.5122320637784544 0.5744038410876726 0.6790209314506575 0.8980549195595404 1.1143537647191921 1.0113907903362844 1.2196274145756767 1.2264424063821147 1.0 13.94123888197906 -6.371247680158855 1.3318505650954697 1.1396320387212315 0.5361256679697545 0.9242628556871699 0.07197010844721535 0.1035901271091678 0.3746949676123503 0.02911185827094055 0.03727161889129964 4.25355761582501e-07 6.371247680158855 -0.6035063707514771 RIDIS(ph)PSTFR ddPTM_PC-9_AZD4547_30min_R2 3 RIDISPSTFR 10 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 RIDIS(0.803)PS(0.034)T(0.162)FR;RIDIS(0.782)PS(0.161)T(0.057)FR;RIDIS(0.46)PS(0.27)T(0.27)FR 60.901 0.030345999999999998 966140000.0 36994.0 35258.6 61837.0 101433.0 89817.0 74016.0 52325.0 67448.0 45328.0 63282.0 True False 48757.32247699836 46655.25293049745 61017.00097642194 78049.1889742281 77347.4599042723 69387.76781933045 56981.82363304356 57025.46140085066 47723.94554105392 61066.516441541724 0.798429733971696 0.7640071130495873 0.9991891552358783 1.278101216874614 1.2666099920455776 1.1362653686943902 0.9331107610762701 0.9338253551017681 0.7815075809464178 1.0 15.89809392808977 -10.987159045114462 3.176386087967315 1.000009199298215 0.9995366999919257 0.0 0.17883133508896104 196432900908.32526 33123868111.28449 13606470.452995418 0.04917315542734371 1.0300088467674291e-11 10.987159045114462 -0.0004724993062892313 RIDIS(ph)PSTFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RIDISPSTFR 10 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 RIDIS(0.956)PS(0.034)T(0.01)FR;RIDIS(0.489)PS(0.255)T(0.255)FR;RIDIS(0.939)PS(0.03)T(0.03)FR 81.23899999999999 0.0075902 389993000.0 27320.1 22329.0 26335.9 33641.5 33584.7 27047.0 31455.7 26946.2 28696.1 23517.2 True False 31944.853333428848 24545.67555277994 26963.847735456948 31756.67582221458 27004.019124786206 25628.607706477727 28475.988376453475 26238.89080185889 29115.726174812455 27780.682197947244 1.149894488040661 0.8835519364817346 0.9705970336988106 1.1431208058872337 0.9720430525201995 0.9225334181451982 1.0250284054780199 0.94450131263507 1.0480565584153962 1.0 14.761794406928905 RIDIS(ph)PSTFR ddPTM_PC-9_Lapatinib_30min_R1 4 RIDISPSTFR 10 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 RIDIS(0.954)PS(0.033)T(0.012)FR;RIDIS(0.932)PS(0.034)T(0.034)FR;RIDIS(0.983)PS(0.016)T(0.001)FR;RIDIS(0.711)PS(0.144)T(0.144)FR 86.262 0.005215999999999999 890821000.0 71157.0 65358.0 80196.0 58936.5 73847.0 67816.1 62112.0 67179.1 74578.0 62845.3 True False 70142.2881314042 65206.66756658354 73602.59444551224 63270.886816400496 69503.46464878815 64915.76349005031 65327.85544364992 70300.48623536194 66178.24029884432 73708.02636890154 0.9516234742244872 0.8846616953251534 0.9985696005091544 0.8583988736821663 0.9429565282474128 0.8807149870646813 0.8863058565249098 0.9537697547824006 0.8978430648465424 1.0 16.169534108396423 -10.81700761203948 4.159538285963119 1.0000964325186574 0.9167620235795456 0.266393087607501 0.04121299178817559 3.426390684095983e-05 5.814624081370209e-06 0.03709816553238323 0.008987222494791936 1.524026041396955e-11 10.81700761203948 -0.08333440893911181 RIDIS(ph)PSTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RIDISPSTLR 10 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 RIDIS(0.974)PS(0.024)T(0.002)LR 63.727 0.024709000000000002 116680000.0 31016.0 31984.0 39257.0 32461.0 44711.0 32561.0 39945.0 34027.0 38141.0 30602.0 True False 36266.396206076475 35159.16014510785 40193.03576300157 30642.315409981948 35950.20051059907 30853.443839635496 36161.12042324395 33133.82730458664 38698.73996931714 36149.90035470127 1.0032225773856125 0.9725935562789298 1.1118436114243533 0.8476459162908021 0.9944757843827299 0.8534862762249088 1.0003103761955798 0.9165675971297002 1.070507514256105 1.0 15.141704050018333 -5.754372469808949 24.999649804667666 0.9505758503784583 1.023557235072416 0.17697238294381556 0.07294512106299438 281.5702387349814 996060.9970263526 0.01887701056100653 0.03181929078777227 1.7604655470596868e-06 5.754372469808949 0.07298138469395776 RIDIS(ph)PSTLR ddPTM_PC-9_Lapatinib_30min_R1 4 RIDISPSTLR 10 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 RIDIS(0.991)PS(0.007)T(0.002)LR;RIDIS(0.983)PS(0.015)T(0.001)LR;RIDIS(0.94)PS(0.045)T(0.015)LR;RIDIS(0.995)PS(0.004)T(0.001)LR 76.868 0.010336 647005700.0 42373.6 33696.4 47205.1 31058.200000000004 38948.3 37899.7 36291.5 35121.1 49343.4 30014.9 True False 41769.34469363345 33618.37805610065 43324.0788949555 33342.323635117966 36657.43756930399 36278.818179515794 38170.496294326695 36752.95452187914 43785.82668296269 35202.93547265972 1.1865301609882368 0.9549879180447972 1.2306950631603732 0.9471461168632713 1.0413176366435095 1.0305623009107197 1.0842986751480348 1.0440309601573776 1.2438118041880015 1.0 15.103408115664067 RIDT(ph)PSLEEPSDLEELEQFAK ddPTM_PC-9_AZD4547_30min_R2 1 RIDTPSLEEPSDLEELEQFAK 21 1 A0A0C4DG88;P14859-4;P14859-5;P14859-3;P14859;P14859-2;P14859-6 A0A0C4DG88 POU2F1 POU domain protein;POU domain, class 2, transcription factor 1 1 RIDT(0.939)PS(0.06)LEEPSDLEELEQFAK 122.44 1.1897e-06 3473300.0 17997.0 18642.0 21599.0 33153.0 31663.0 24238.0 20903.0 30472.0 23197.0 28354.0 True False 23719.671639145243 24667.661935820866 21312.583147464105 25510.088058744044 27267.138993163597 22722.394028384802 22763.326505523353 25763.25257689953 24423.146062385917 27361.33509028592 0.8669047603443307 0.9015518378187113 0.7789306726860232 0.9323407638759877 0.9965573281855035 0.830456333852361 0.8319523309228066 0.9415934014874239 0.8926152902186726 1.0 14.739851007475796 -14.522878745280057 0.2091454695146135 1.547604246176446 0.8698908718306912 0.26141329004594627 0.05910762302459337 218.66298810286415 2.1725882816299045 50.11515797254523 0.13313435885804234 3.00000000000194e-15 14.522878745280057 -0.6777133743457548 RIDT(ph)PSLEEPSDLEELEQFAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RIDTPSLEEPSDLEELEQFAK 21 1 A0A0C4DG88;P14859-4;P14859-5;P14859-3;P14859;P14859-2;P14859-6 A0A0C4DG88 POU2F1 POU domain protein;POU domain, class 2, transcription factor 1 1 RIDT(0.766)PS(0.234)LEEPS(0.001)DLEELEQFAK;RIDT(0.957)PS(0.043)LEEPSDLEELEQFAK 149.99 6.6319e-05 4106500.0 46161.2 41270.4 43986.2 54564.5 57408.9 46477.4 43524.5 44643.1 40622.5 43457.9 True False 53975.379434741306 45367.45256542829 45034.99782659246 51507.42796549582 46160.038158236865 44040.04332521342 39401.54426990814 43471.265928274384 41216.527212280365 51336.473257452904 1.051404118940042 0.883727488211161 0.8772514933143443 1.0033300828279648 0.8991665229269613 0.8578704482552235 0.7675156038146411 0.8467910467917337 0.8028702518300992 1.0 15.647696567773867 -6.648108880139429 3.2115645903394183 0.8391291974446531 0.9440912195973017 0.26279328876498254 0.07483469123817385 0.3136314067050955 6.4234871049888085 0.025416566329626387 0.02517198810891532 2.2484908255075806e-07 6.648108880139429 0.1049620221526486 RIDT(ph)PSLEEPSDLEELEQFAK ddPTM_PC-9_Lapatinib_30min_R1 1 RIDTPSLEEPSDLEELEQFAK 21 1 A0A0C4DG88;P14859-4;P14859-5;P14859-3;P14859;P14859-2;P14859-6 A0A0C4DG88 POU2F1 POU domain protein;POU domain, class 2, transcription factor 1 1 RIDT(0.707)PS(0.293)LEEPSDLEELEQFAK 120.85 1.579e-06 2686900.0 53940.0 40313.0 52561.0 38990.0 41753.0 39878.0 36558.0 31911.0 39186.0 36668.0 True False 53170.80570861546 40219.657725323326 48239.63747132738 41857.454666827136 39297.17062955634 38172.510900158355 38450.794360332184 33393.701556832915 34772.460033126554 43006.014942961185 1.2363574206802426 0.93521005791089 1.1216951288164585 0.9732930317385281 0.9137598701408657 0.8876086508081835 0.8940794540328699 0.7764890934703653 0.8085487594989961 1.0 15.392250832887608 -5.715710692104983 0.6609883828048247 0.8469146563360589 1.1725705106776807 0.5583675412338716 0.08740024687402946 0.9169717709437609 0.6499363058046734 0.04696821275595475 0.1921770358754385 1.924373234887149e-06 5.715710692104983 0.3256558543416218 RIDTPS(ph)LEEPSDLEELEQFAK ddPTM_PC-9_AZD4547_30min_R2 1 RIDTPSLEEPSDLEELEQFAK 21 1 A0A0C4DG88;P14859-4;P14859-5;P14859-3;P14859;P14859-2;P14859-6 A0A0C4DG88 POU2F1 POU domain protein;POU domain, class 2, transcription factor 1 1 RIDT(0.026)PS(0.973)LEEPS(0.002)DLEELEQFAK 144.72 7.8106e-05 3307100.0 15622.0 14740.0 20739.0 29464.0 27063.0 21656.0 16282.0 23089.0 22575.0 19040.0 True False 20589.471042214092 19504.416743589725 20463.987309378117 22671.530014262185 23305.76959138384 20301.84689655504 17731.066457586523 19521.125582437428 23768.26841222407 18373.415395324966 1.1206120690796002 1.0615564022219046 1.1137824334274338 1.2339311731900895 1.2684505896118743 1.1049577043645762 0.9650392197684767 1.0624658052092204 1.2936227642396743 1.0 14.165332210457072 -6.987770560054222 24.98522269054857 1.0782747047759795 1.1588838173722809 0.12962722858343412 0.09807261747213053 508.25670542648743 1038384.4796080941 0.03662805444304005 0.03227953773075322 1.0285595477638242e-07 6.987770560054222 0.08060911259630132 RIDTPS(ph)LEEPSDLEELEQFAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RIDTPSLEEPSDLEELEQFAK 21 1 A0A0C4DG88;P14859-4;P14859-5;P14859-3;P14859;P14859-2;P14859-6 A0A0C4DG88 POU2F1 POU domain protein;POU domain, class 2, transcription factor 1 1 RIDT(0.189)PS(0.804)LEEPS(0.007)DLEELEQFAK 70.615 0.021449 0.0 3863.3 3093.2 5130.1 6935.8 7707.8 3606.7 6479.1 5373.4 5012.4 4434.2 True False 4517.2803863468935 3400.2724537533663 5252.421040012594 6547.20961216699 6197.511920905268 3417.558302767522 5865.352743378136 5232.353943587911 5085.696867470836 5238.085358892114 0.8623915184349583 0.6491441472944123 1.0027368170119917 1.2499241924441957 1.1831635981999498 0.6524441792392547 1.1197512719836038 0.9989058186509937 0.9709075967686199 1.0 12.354823854439744 -5.328685691976909 7.452966977961304 1.027106444237789 0.7565625291063478 0.3116756348355424 0.15837212786955723 0.30359163596372596 29.838213441012044 0.04276264745431242 0.08990098157502888 4.691527950255685e-06 5.328685691976909 -0.27054391513144127 RIEQHYFEDR ddPTM_PC-9_AZD4547_30min_R2 4 RIEQHYFEDR 10 1 O75431-2;O75431;C9JNK6 O75431-2 MTX2 Metaxin-2 0 ;;; 108.43 0.00080503 33029600.0 40014.7 40439.9 59439.8 85538.0 67851.0 58429.0 51934.4 64813.1 47702.3 53646.9 False True 52738.54224253514 53511.30682965364 58651.58941472463 65818.53564892618 58431.059843512674 54775.425393369725 56556.46098973601 54797.724651872115 50223.74619182443 51768.73835984554 1.0187333884003213 1.033660632362633 1.1329538109860096 1.2713953968014482 1.128693912479713 1.0580792024063759 1.092482891829639 1.058509949981242 0.9701558852510208 1.0 15.659793538695299 -7.928778086943126 1.4220147654482511 0.9831697311900593 1.113905620614074 0.33025318557415084 0.06706097302835352 0.557770369787663 2.033182995442744 0.0658134798904238 0.02295690138263408 1.1782078529575369e-08 7.928778086943126 0.1307358894240147 RIEQHYFEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RIEQHYFEDR 10 1 O75431-2;O75431;C9JNK6 O75431-2 MTX2 Metaxin-2 0 ;;; 123.11 0.00019143 22898400.0 56541.0 61437.0 70445.0 70026.0 77681.0 74579.0 71372.0 74555.0 65175.0 52592.3 False True 66112.27456434641 67536.05933701208 72124.67596415036 66102.67024735513 62459.96568772443 70667.94595117398 64611.127471467364 72598.0102475522 66128.06107601382 62126.86766958225 1.0641494902971818 1.0870668660811658 1.1609256778844994 1.0639948982929242 1.0053615775370124 1.1374780123636188 1.0399868832128716 1.1685445117506978 1.064403591497831 1.0 15.92292969744599 RIEQHYFEDR ddPTM_PC-9_Lapatinib_30min_R1 3 RIEQHYFEDR 10 1 O75431-2;O75431;C9JNK6 O75431-2 MTX2 Metaxin-2 0 ;; 131.09 7.5963e-05 16711500.0 65418.1 51282.4 65703.0 55508.6 62655.3 69238.9 51861.4 51825.9 72486.7 49224.4 False True 64485.225897789715 51163.65875358124 60301.15296091434 59590.88761526135 58970.03843905927 66277.71365075913 54546.529532220935 54233.92051374972 64322.48452720958 57732.77195260988 1.116960501233556 0.8862151776737671 1.0444874015474732 1.0321847643861048 1.0214309212013066 1.1480085124816697 0.9448105068815268 0.9393957483674575 1.1141416279129794 1.0 15.817102875400558 RIEYIEAR ddPTM_PC-9_AZD4547_30min_R2 2 RIEYIEAR 8 1 Q8WUW1;Q8WUW1-2 Q8WUW1 BRK1 Protein BRICK1 0 ; 131.62 3.9722e-05 0.0 16126.4 16861.2 25522.0 35476.0 30865.0 24761.0 22423.9 31133.0 21045.5 24196.0 False True 21254.25975004233 22311.253161262906 25183.56160422143 27297.556298736254 26579.927518680932 23212.690755707383 24419.583659149663 26322.110215168475 22157.922164760213 23348.90540468923 0.9102893425476714 0.955558848458141 1.0785756834306992 1.1691150324012192 1.1383800250157683 0.994166122710211 1.0458556080425683 1.127338081119731 0.9489919026486857 1.0 14.511067297611081 -5.162022067945614 3.821928468538443 1.070833721110993 0.920518853661242 0.38127276899752616 0.06643670209566165 0.231413830918004 6.034752644939783 0.01766316293850276 0.054511347035915925 6.886173045220132e-06 5.162022067945614 -0.1503148674497511 RIEYIEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RIEYIEAR 8 1 Q8WUW1;Q8WUW1-2 Q8WUW1 BRK1 Protein BRICK1 0 109.44 0.0023905999999999997 3193400.0 7671.3 8229.0 7687.3 8446.6 9166.1 10299.0 9182.8 8959.5 9612.5 8182.5 False True 8969.899574918565 9045.920736433614 7870.594386247602 7973.364386246682 7370.068504399408 9758.90230964668 8312.938706285255 8724.322618374936 9753.06462743665 9665.922477365642 0.927992087244965 0.9358569508100375 0.8142621053166836 0.8248943031477477 0.7624795793321997 1.0096193438855698 0.8600253856526758 0.9025856185795387 1.0090153992311717 1.0 13.238691708770924 -8.185952840872885 3.522890061690476 1.0069582235564762 0.8753187706171142 0.36627754600205054 0.06625076444772741 0.27086365302591237 6.173079596634367 0.056652200497723536 0.018048739792421362 6.5169915686367336e-09 8.185952840872885 -0.13163945293936208 RIEYIEAR ddPTM_PC-9_Lapatinib_30min_R1 2 RIEYIEAR 8 1 Q8WUW1;Q8WUW1-2 Q8WUW1 BRK1 Protein BRICK1 0 ; 125.71 0.00010072 1980300.0 29819.0 23757.0 23466.0 21647.0 25599.0 28566.0 21997.0 23945.0 25511.0 19912.3 False True 29393.775591865127 23701.992126125733 21536.71606137951 23238.99259227512 24093.317149570415 27344.298770598405 23135.89702785239 25057.57211552019 22637.68253726055 23354.11452352804 1.258612291305348 1.0148957736011455 0.9221808020031076 0.9950705931866122 1.0316519226322056 1.1708557283578647 0.9906561434621807 1.0729403630472056 0.9693230935582797 1.0 14.511389125619585 -7.000023912017445 0.009377980378896969 1.6858962847212947e-07 2.077343307767008 0.08128064680592229 0.09171634468507897 8597.546946317727 38.04025432248419 4125.490189580909 4296.660261044368 9.999449420608312e-08 7.000023912017445 2.0773431391773793 RILES(ph)HNNTLVDPCEEHKKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RILESHNNTLVDPCEEHKKK 20 3 P23497 P23497 SP100 Nuclear autoantigen Sp-100 1 RILES(0.835)HNNT(0.165)LVDPCEEHKKK 69.52199999999999 0.026496 0.0 2755.8 2645.7 3718.8 3478.7 3006.3 3085.7 2722.3 3661.4 2911.5 2159.0 True False 3222.3025104689696 2908.3476111778327 3807.470295627539 3283.799717097569 2417.2370959051223 2923.880459935605 2464.424036254774 3565.29212957397 2954.0751794831513 2550.4096093654025 1.263445094715883 1.1403453000247648 1.492885802204502 1.2875577730883196 0.9477838724527796 1.1464356349657614 0.9662855829922851 1.3979292253612128 1.1582747997166578 1.0 11.316513254861302 -6.048394545064666 22.812518247544535 1.1180052010316435 1.3009014071478247 0.2953796489158482 0.14517093615560414 202.27867353655847 95350.7209250091 0.043697966200404614 0.05641660706412768 8.945517196829412e-07 6.048394545064666 0.18289620611618118 RILS(ph)DVTHSAVFGVPASK ddPTM_PC-9_AZD4547_30min_R2 1 RILSDVTHSAVFGVPASK 18 1 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 1 RILS(0.826)DVT(0.137)HS(0.037)AVFGVPASK 48.198 0.038697 5214200.0 22568.0 18780.0 40044.0 79744.0 62997.0 40246.0 31371.0 42937.0 32056.0 45518.0 True False 29744.154556438843 24850.267737083806 39512.990395715184 61360.25283251846 54250.95395737383 37729.411257792475 34162.958226320305 36302.07324410396 33750.41471637897 43924.428674600924 0.6771665666226012 0.5657505057419984 0.8995675433466336 1.3969505053118587 1.2350975435394602 0.858961912454181 0.7777667065269049 0.8264666004658917 0.7683745864153942 1.0 15.422735900759072 -5.3534381338397585 5.120108966899564 0.9817979142256454 0.6234487312145272 0.3476769913482156 0.19282430274464005 0.2589555868706762 10.852405654639579 0.058501808616900866 0.1266373971894639 4.431613392557413e-06 5.3534381338397585 -0.3583491830111183 RINPPSSGGTSS(ph)SPIK ddPTM_PC-9_Lapatinib_30min_R1 2 RINPPSSGGTSSSPIK 16 1 A0A0C4DG88;P14859-4;P14859-5;P14859-3;P14859;P14859-2;P14859-6;A0A0A0MT46 A0A0C4DG88 POU2F1 POU domain protein;POU domain, class 2, transcription factor 1 1 RINPPS(0.001)S(0.043)GGT(0.025)S(0.025)S(0.586)S(0.32)PIK;RINPPSSGGT(0.002)S(0.056)S(0.562)S(0.38)PIK 98.508 0.0050358 15655000.0 70510.0 46045.0 59619.0 44832.0 53947.0 43850.0 35971.0 42944.0 41869.0 45969.0 True False 69504.5144700495 45938.38563149634 54717.35595599528 48129.0948351678 50773.94352388278 41974.637719342565 37833.40237254528 44939.33501477964 37153.272319884 53914.68040015771 1.2891574976274214 0.852057088914172 1.0148878848929468 0.8926899775339671 0.9417461653678699 0.778538190485495 0.7017272863669727 0.833526873965262 0.689112353891934 1.0 15.718390536697699 -1.522878745286836 0.5844492123697016 0.808455607528113 24.2359505180081 0.5610639273139147 0.11119537885804993 117.56947665843202 0.9613331631258247 0.0506221108285078 3500.34976591068 0.029999999999551104 1.522878745286836 23.427494910479986 RINPPSSGGTSSS(ph)PIK ddPTM_PC-9_AZD4547_30min_R2 1 RINPPSSGGTSSSPIK 16 1 A0A0C4DG88;P14859-4;P14859-5;P14859-3;P14859;P14859-2;P14859-6;A0A0A0MT46 A0A0C4DG88 POU2F1 POU domain protein;POU domain, class 2, transcription factor 1 1 RINPPSSGGTS(0.003)S(0.054)S(0.943)PIK 97.352 0.0010084 12161000.0 43733.0 36292.0 52356.0 76653.0 72926.0 62215.0 55165.0 59966.0 43776.0 69758.0 True False 57639.184297090585 48022.67927125906 51661.72523119728 58981.83512704446 62801.483694389266 58324.68621486752 60074.578131234535 50699.632581594844 46089.90998952472 67315.79365268274 0.8562505345250949 0.7133939401952696 0.7674532591526297 0.8761960890094008 0.9329383237820065 0.8664339087465116 0.8924291740685788 0.7531610314687912 0.6846819667213104 1.0 16.03865740966338 -5.7531596671416745 24.7698777688444 0.852603497459274 0.7724686855941332 0.13882101410363046 0.08895741437986696 343.343698716511 1027146.662386995 0.025131708655538664 0.04260100887941748 1.765388661199295e-06 5.7531596671416745 -0.08013481186514082 RINPPSSGGTSSS(ph)PIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RINPPSSGGTSSSPIK 16 1 A0A0C4DG88;P14859-4;P14859-5;P14859-3;P14859;P14859-2;P14859-6;A0A0A0MT46 A0A0C4DG88 POU2F1 POU domain protein;POU domain, class 2, transcription factor 1 1 RINPPSSGGT(0.001)S(0.025)S(0.257)S(0.717)PIK;RINPPSSGGTS(0.002)S(0.093)S(0.904)PIK;RINPPSSGGTSS(0.043)S(0.957)PIK;RINPPSSGGTSS(0.081)S(0.919)PIK 183.75 3.8366e-30 20397800.0 164546.0 151816.0 168695.0 195001.0 233844.0 213371.0 189646.0 207553.0 180853.0 147293.0 True False 192400.38786836047 166887.2891630092 172717.32857935043 184075.7261717722 188023.9468631993 202181.4491418217 171681.35796186046 202104.9536705818 183497.63298473856 173996.05492925338 1.105774426590248 0.9591440980134027 0.9926508313626831 1.0579304585188278 1.0806218965116745 1.1619886969507929 0.9866968422454516 1.1615490578378773 1.0546080085513923 1.0 17.408695070174467 -5.947488384318247 4.424320204242878 1.0815293841625002 1.0135877992586246 0.1199346079451391 0.06417482867940116 0.3455019866691776 14.312484970682469 0.017666756946917706 0.026436799019467182 1.1285261207916863e-06 5.947488384318247 -0.06794158490387558 RIPHS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 1 RIPHSPAR 8 1 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 RIPHS(1)PAR 65.695 0.023417 26808000.0 5261.9 4999.2 7069.2 8037.7 6165.0 7786.3 7176.6 7185.3 7079.8 8049.4 True False 6935.074745680858 6615.093635315725 6975.457789066771 6184.732446227099 5309.096165646133 7299.421430118512 7815.30349708362 6074.97698676806 7454.023774301836 7767.592956046676 0.892821596719001 0.8516272251581117 0.8980205101551738 0.7962225210851966 0.6834930969848609 0.9397275927591293 1.0061422555619117 0.7820926020639379 0.9596311001980682 1.0 12.923251886078416 RIPHS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 1 RIPHSPAR 8 1 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 RIPHS(1)PAR 63.693999999999996 0.026136000000000003 20894000.0 39064.0 30318.0 35307.0 29655.0 33264.0 32018.0 39715.0 33233.0 36358.0 30139.0 True False 38506.94019653978 30247.800533732352 32404.194748961323 31835.92762618001 31307.47691954023 30648.664777603444 41771.248373012575 34777.12650303122 32262.979173286767 35348.48599230688 1.0893518948709795 0.8557028592487773 0.9167067227720491 0.9006305852281388 0.8856808443324525 0.867043210401535 1.181698372657418 0.9838363801663244 0.912711768767363 1.0 15.109360803971201 RIPSIVS(ph)SPLNSPLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RIPSIVSSPLNSPLDR 16 1 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 RIPS(0.007)IVS(0.589)S(0.403)PLNSPLDR 55.707 0.029570999999999997 10326000.0 9795.0 7528.3 11017.0 12151.0 10254.0 10566.0 9986.6 11380.0 10376.0 8595.7 True False 11453.100039931614 8275.659871198584 11279.687062205174 11470.218864073526 8244.802308954906 10011.90035962005 9040.596951277203 11081.287058106675 10527.729370536554 10154.032366476242 1.1279361367553125 0.8150121619191263 1.1108578991185123 1.1296220506389858 0.8119732153085606 0.9860024075434854 0.890345492803916 1.0913188631042565 1.03680281789273 1.0 13.309765143398161 -7.789665205283772 24.999931387072934 1.0480455945017357 0.9795659092391832 0.05626033970829403 0.11368487361426394 666.5100592263605 590326.3437024719 0.06130251904790305 0.02945839751816824 1.6230608219595167e-08 7.789665205283772 -0.06847968526255255 RIPSIVSS(ph)PLNSPLDR ddPTM_PC-9_AZD4547_30min_R2 1 RIPSIVSSPLNSPLDR 16 1 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 RIPSIVS(0.044)S(0.956)PLNS(0.001)PLDR 125.92 1.3762e-05 16095000.0 30766.0 22213.0 30163.0 49463.0 45973.0 27326.0 25416.0 33760.0 30296.0 27340.0 True False 40548.948027445826 29392.917851109825 29763.01891184592 38060.0695457321 39590.44250174366 25617.30090022455 27677.974762683905 28543.167727623015 31897.38470949017 26382.834921648348 1.5369443104908154 1.114092474838311 1.128120575375468 1.4426072732048227 1.500613661091358 0.9709836329682812 1.0490902454145605 1.0818840284749693 1.2090203651055282 1.0 14.687311974755188 -6.772550776345888 24.99816488156228 1.0664943076008386 1.3251086370775207 0.48766874662000315 0.1439485222016856 221.21535997205018 497682.3464231934 0.05333168045002531 0.04746343575495708 1.688298457397646e-07 6.772550776345888 0.25861432947668206 RIPSIVSSPLNS(ph)PLDR ddPTM_PC-9_AZD4547_30min_R2 2 RIPSIVSSPLNSPLDR 16 1 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 RIPSIVSSPLNS(1)PLDR;RIPSIVSSPLNS(1)PLDR 109.23 0.00032389 17637100.0 19554.0 17702.6 20075.5 33343.0 34091.0 24117.9 21248.7 22811.4 20988.6 25220.0 True False 25771.76525153338 23424.6192567891 19809.28575290131 25656.28649421476 29358.053103494294 22609.803900370556 23139.793135813725 19286.422283824042 22098.014546923856 24337.055476370577 1.0589516581640617 0.9625083560142523 0.8139557298595392 1.054206681622806 1.20631080994982 0.9290279147501205 0.9508049631674094 0.7924714763686053 0.9079986922978148 1.0 14.570867007477348 -6.980457158100317 24.99913357754074 0.9018663251185348 1.0126904538598198 0.19555204518585523 0.10363219540890092 419.5171182892989 536643.1002088147 0.03924872733795805 0.03460981483061583 1.0460268729117596e-07 6.980457158100317 0.110824128741285 RIPSIVSSPLNS(ph)PLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RIPSIVSSPLNSPLDR 16 1 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 RIPSIVS(0.007)S(0.02)PLNS(0.973)PLDR;RIPSIVS(0.002)S(0.014)PLNS(0.984)PLDR 67.877 0.0111 8216600.0 20066.0 16471.5 21894.9 26972.0 28085.6 23443.8 27515.0 25593.0 28082.0 25651.0 True False 23462.7774784347 18106.68166364883 22416.957452870654 25460.84628440382 22582.428294166537 22214.36585754879 24908.580008650802 24921.210868024995 28492.6461240755 30301.32324679571 0.7743152761790966 0.597554156832526 0.7398012710630119 0.8402552613637505 0.7452621164507914 0.7331153717815906 0.8220294475517608 0.8224462893930005 0.9403102924585489 1.0 14.8870931765449 -8.103086282354152 0.5117445710450216 1.0129978407531803 0.7116452490315992 0.7025523452332512 0.05848923771264432 0.49655417912628824 0.3238068854254765 0.06459344821927611 0.03695684164416275 7.8870340840387e-09 8.103086282354152 -0.30135259172158113 RIPSIVSSPLNS(ph)PLDR ddPTM_PC-9_Lapatinib_30min_R1 1 RIPSIVSSPLNSPLDR 16 1 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 RIPSIVS(0.005)S(0.004)PLNS(0.991)PLDR 69.398 0.009885600000000001 4684900.0 8218.6 4717.7 7507.7 6342.7 5941.4 10941.0 11080.0 9141.0 12137.0 11478.0 True False 8101.4012568933495 4706.776455504623 6890.4458865600855 6809.163316626942 5591.938533241833 10473.078934716701 11653.668185143628 9565.724230861138 10770.003251724002 13461.957006526358 0.601799667980353 0.34963538014738704 0.5118457801655136 0.5058078341303467 0.4153882329687178 0.7779759606749116 0.8656741497164141 0.7105745640268851 0.8000325098722796 1.0 13.716600533805261 -6.811817495730005 6.124726708314372 0.8182571803267938 0.4734256336313078 0.7846075023656359 0.09269133661159727 0.08893329627901116 7.416845601563902 0.031149030045616043 0.027768734064215136 1.542348460362413e-07 6.811817495730005 -0.34483154669548605 RIPVS(ph)PEQAR ddPTM_PC-9_Lapatinib_30min_R1 1 RIPVSPEQAR 10 1 C9J7L6;Q9H981-2;Q9H981 C9J7L6 ACTR8 Actin-related protein 8 1 RIPVS(1)PEQAR 55.213 0.041689 10859000.0 18694.0 12278.0 14105.0 12854.0 15227.0 11630.0 12003.0 16872.0 15586.0 13027.0 True False 18427.420131940256 12249.571045358076 12945.34134687453 13799.32603968699 14331.377797433832 11132.612010854149 12624.456608869941 17655.934714264222 13830.540552143884 15278.699592613613 1.2060856370818935 0.8017417301194959 0.8472803112859729 0.9031741187161101 0.9379972235570521 0.728636095197273 0.8262782138195289 1.155591456409017 0.9052171271716193 1.0 13.89923413685475 -7.7403341589918035 24.99602254831386 1.0228033512394143 0.8835542077697023 0.16035127977975472 0.13215294479426926 380.44798025121213 450585.49089414947 0.06099593041676615 0.035168887921622684 1.818301265577285e-08 7.7403341589918035 -0.13924914346971207 RIS(ph)ACLSDYSLASDSGVFEPLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RISACLSDYSLASDSGVFEPLTK 23 1 Q9ULE0 Q9ULE0 WWC3 Protein WWC3 1 RIS(0.57)ACLS(0.43)DYSLASDSGVFEPLTK 96.44 0.001546 0.0 4150.7 3055.8 2577.7 2376.7 3072.9 3779.1 3024.8 4303.2 2772.1 3044.4 True False 4853.331529938145 3359.1596289213558 2639.1621439816886 2243.5412043653637 2470.787303997223 3580.917343274668 2738.2690463444283 4190.24555961728 2812.636718202042 3596.3256205428597 1.3495250547433861 0.9340532486083104 0.733849607195277 0.6238426219110562 0.6870310324192116 0.9957155500102168 0.761407429489405 1.165146319254809 0.7820862221528981 1.0 11.81230793673653 -9.768243859537447 24.85670121167732 1.0 0.8823240313600597 0.01992330505292006 0.21574612008077193 0.0 0.0 0.2145736241237337 0.052041748043160946 1.7051246801318124e-10 9.768243859537447 -0.11767596863994034 RIS(ph)AVSVAER ddPTM_PC-9_AZD4547_30min_R2 3 RISAVSVAER 10 1 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 1 RIS(0.997)AVS(0.003)VAER;RIS(0.998)AVS(0.002)VAER;RIS(0.997)AVS(0.003)VAER 86.49799999999999 0.0051471 16649100.0 26524.7 26339.7 40196.7 44375.0 38518.0 37061.2 30889.1 38694.0 32176.800000000003 39503.5 True False 34959.00285196623 34853.492924092985 39663.66549394281 34145.029336915715 33170.44056907667 34743.757305255145 33638.17005988428 32714.73139966365 33877.59995776089 38120.49448892961 0.9170658282546285 0.9142980276453292 1.0404814005091498 0.8957131798705185 0.870147174473551 0.9114193761401734 0.8824169389946654 0.8581927343351797 0.8886978097201526 1.0 15.21827921317557 -5.944974149685108 24.999997412556066 0.8932043667458849 0.9555025219999446 0.20625885268245525 0.04901817996107003 120.58410186983768 54784.12843709597 0.013312245289104307 0.019745248562098743 1.135078376420697e-06 5.944974149685108 0.062298155254059684 RIS(ph)AVSVAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RISAVSVAER 10 1 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 1 RIS(0.989)AVS(0.011)VAER;RIS(0.99)AVS(0.01)VAER;RIS(0.999)AVS(0.001)VAER 68.83 0.018322 17823600.0 30650.6 30808.0 30813.2 35325.6 38402.0 40051.0 36176.0 38096.4 27489.4 24170.9 True False 35839.14120305542 33866.41463702108 31547.903547711754 33346.42115914045 30877.40377106361 37950.655054244045 32749.14738844093 37096.40986647236 27891.380470164564 28552.892833260863 1.2551842439343628 1.186093991764315 1.1048934247027344 1.1678824052565235 1.0814106980815252 1.3291352044734277 1.1469642526130281 1.2992172135798188 0.9768320370563044 1.0 14.801349299035108 -8.279605128252218 24.839659763888072 0.988415937347157 1.1909574755456045 0.5469603423680223 0.0755683486755415 656.6604035520567 897901.0556105104 0.07067676012933581 0.018389917625522268 5.252848457254182e-09 8.279605128252218 0.20254153819844745 RIS(ph)AVSVAER ddPTM_PC-9_Lapatinib_30min_R1 2 RISAVSVAER 10 1 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 1 RIS(0.999)AVS(0.001)VAER;RIS(1)AVSVAER 87.863 0.0047472 13211100.0 32506.0 30021.0 33809.0 29599.0 30094.0 28814.0 20794.6 28931.0 28824.0 21452.1 True False 32042.45847912968 29951.48821898474 31029.354526514075 31775.809199369458 28323.930087080444 27581.692388714648 21871.242639240772 30275.239877808075 25577.537589823918 25160.06690187353 1.2735442478789138 1.1904375427854852 1.2332779021427598 1.2629461329851746 1.1257493947669637 1.0962487697781436 0.8692839619441609 1.2033052215593927 1.0165925905355722 1.0 14.618848137969865 -6.571712793630496 2.298255606502859 1.036650748122606 1.2356543533317992 0.5857196592541604 0.0805925486650961 0.2253609377169612 2.411313219465928 0.028847528035904717 0.030042303547698827 2.6809406906428197e-07 6.571712793630496 0.19900360520919325 RIS(ph)DPQVFSK ddPTM_PC-9_AZD4547_30min_R2 4 RISDPQVFSK 10 1 C9JYJ6;Q4L180-6;Q4L180-5;Q4L180-3;Q4L180-7;Q4L180-2;Q4L180 C9JYJ6 FILIP1L Filamin A-interacting protein 1-like 1 RIS(1)DPQVFSK;RIS(1)DPQVFSK;RIS(1)DPQVFSK;RIS(1)DPQVFSK 68.972 0.018152 35311400.0 208327.0 171272.0 215691.0 303428.0 281110.0 232031.0 181594.0 237409.0 232374.0 214853.0 True False 274570.6525292107 226632.32459349366 212830.7964100044 233477.36251586847 242082.72881180557 217522.0648898492 197755.5142058081 200722.89416609178 244656.81523907642 207331.0618661634 1.3243102604010775 1.0930939269475677 1.026526341467306 1.1261089410065486 1.1676143778594792 1.0491532862078539 0.95381518054185 0.9681274593368102 1.1800297217259592 1.0 17.661576748352694 -6.8872548331743735 5.305861390380711 1.0201573334723752 1.136144776638803 0.2889789929212674 0.09141384959031915 0.3015109051174919 12.857788749722298 0.03330687602019996 0.029348160249082347 1.2964183417973216e-07 6.8872548331743735 0.11598744316642784 RIS(ph)DPQVFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RISDPQVFSK 10 1 C9JYJ6;Q4L180-6;Q4L180-5;Q4L180-3;Q4L180-7;Q4L180-2;Q4L180 C9JYJ6 FILIP1L Filamin A-interacting protein 1-like 1 RIS(1)DPQVFSK;RIS(1)DPQVFSK;RIS(1)DPQVFSK 105.58 0.0011184 13397800.0 124679.0 126497.0 123734.0 160430.0 133069.0 118098.0 119157.0 114762.0 107289.0 87309.0 True False 145784.69217750191 139054.78617045094 126684.28782380783 151441.627221078 106995.08469380936 111904.73298035281 107869.58633802646 111749.6191003903 108857.89865415331 103137.43056233649 1.4134993608299105 1.3482475315923828 1.2283056416384115 1.4683478771516063 1.03740304669643 1.0850060193492734 1.04588204059272 1.083502066040404 1.055464520112893 1.0 16.654208484024437 -6.27299569958452 24.995240771940452 1.056808145163433 1.3536967430260356 0.8617572526005224 0.06140559293603375 257.4951956237633 556936.8025993169 0.018430993640578482 0.02107253843021477 5.333401766346116e-07 6.27299569958452 0.2968885978626026 RIS(ph)DPQVFSK ddPTM_PC-9_Lapatinib_30min_R1 4 RISDPQVFSK 10 1 C9JYJ6;Q4L180-6;Q4L180-5;Q4L180-3;Q4L180-7;Q4L180-2;Q4L180 C9JYJ6 FILIP1L Filamin A-interacting protein 1-like 1 RIS(1)DPQVFSK;RIS(1)DPQVFSK;RIS(1)DPQVFSK;RIS(1)DPQVFSK 89.13600000000001 0.0043743 30646500.0 280081.0 206408.0 263975.0 195377.0 240100.0 244810.0 216576.0 220254.0 254357.0 212126.0 True False 276086.9935794345 205930.0749576694 242271.99447296702 209745.67633856556 225977.79005476227 234340.04697998284 227789.24556549365 230487.804916758 225708.63616204684 248791.69645987175 1.1097114473993923 0.8277208519733873 0.9737945354299383 0.843057382232192 0.9083011743167675 0.9419126534947687 0.9155821870535553 0.9264288486972634 0.9072193299604433 1.0 17.924578810081883 -10.354226216019168 17.40695584027093 0.9999999999131274 0.9234700842609116 0.0762926855542877 0.07331970967882384 0.0 0.0 0.0648690533001693 0.015733056387671765 4.423578962388491e-11 10.354226216019168 -0.07652991565221579 RIS(ph)GLIYEETR ddPTM_PC-9_AZD4547_30min_R2 4 RISGLIYEETR 11 1 P62805 P62805 HIST1H4A Histone H4 1 RIS(1)GLIYEETR;RIS(1)GLIYEETR;RIS(1)GLIYEETR;RIS(1)GLIYEETR 79.471 0.0079042 25914000.0 55692.3 53850.8 62988.9 92125.5 64082.4 69433.3 50660.0 74211.3 50710.5 60009.6 True False 73401.29292819745 71257.01799021047 62153.626029783874 70887.38929978656 55185.664902741555 65091.6247747772 55168.64185857594 62743.648791023465 53390.953502462406 57908.68216950067 1.267535198147825 1.2305066411568264 1.0733041005467558 1.2241236830825604 0.9529773919083713 1.1240391308552284 0.952683428317285 1.0834929485594351 0.9219852965430171 1.0 15.821492045274386 -4.406112297116083 0.36841708735580303 0.9788221733934159 1.5916220693140708 0.6059361556974585 0.07538399611363704 5.314073288204906 0.4650222560609439 0.061772493880634195 1.5260513823816049 3.9254342088447746e-05 4.406112297116083 0.6127998959206549 RIS(ph)GLIYEETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RISGLIYEETR 11 1 P62805 P62805 HIST1H4A Histone H4 1 RIS(1)GLIYEETR;RIS(1)GLIYEETR;RIS(1)GLIYEETR;RIS(1)GLIYEETR 86.214 0.0050609999999999995 21692000.0 37800.8 38297.100000000006 38192.1 49683.9 59441.0 45761.3 50600.1 46794.1 43455.399999999994 33726.5 True False 44199.72884016812 42098.98299128346 39102.74450834583 46900.27216037714 47793.96275078881 43361.496869835435 45806.89221500025 45565.80445744727 44090.8530154601 39840.84747117291 1.1094073456180646 1.0566789027704404 0.9814737132948506 1.1771906256339584 1.1996221412049637 1.0883678340730556 1.149746933675146 1.1436956628600006 1.1066745768237565 1.0 15.281960715445772 -5.771696995514127 24.999989734152184 1.1323885755911764 1.049935868553899 0.2388278004481028 0.059457482534941625 250.59377828162377 610751.1317768571 0.01628599406843324 0.024464084512279962 1.6916207530122695e-06 5.771696995514127 -0.08245270703727736 RIS(ph)GLIYEETR ddPTM_PC-9_Lapatinib_30min_R1 2 RISGLIYEETR 11 1 P62805 P62805 HIST1H4A Histone H4 1 RIS(1)GLIYEETR;RIS(1)GLIYEETR 77.726 0.0087934 12330500.0 34740.0 37185.0 36747.0 29240.0 31341.0 40211.0 29145.0 27611.0 43353.0 24205.3 True False 34244.60122946425 37098.90041713959 33725.803507522076 31390.4071417806 29497.583998776758 38491.26926641924 30653.98549241976 28893.907858911163 38470.12861267123 28389.153853465108 1.206256495217255 1.3067983853492482 1.18798199064343 1.1057183072030576 1.0390441416828757 1.3558441884213146 1.0797780606863072 1.0177798185902764 1.3550995148090919 1.0 14.793052229330257 -14.522878745280336 0.0878296208653752 0.5272939996622972 1.307271763545603 0.14704671925807544 0.12057086719476567 446.1016812298524 2.7238311007206804 41.727041902609166 3.0933681649374867 3.0000000000000132e-15 14.522878745280336 0.7799777638833059 RIS(ph)HSLYSGIEGLDESPSR ddPTM_PC-9_AZD4547_30min_R2 1 RISHSLYSGIEGLDESPSR 19 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3;B1AP52 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 RIS(0.625)HS(0.369)LY(0.005)S(0.001)GIEGLDESPSR 86.179 0.00057334 8911100.0 3005.1 2675.1 10383.0 10059.0 10148.0 10741.0 6236.6 12524.0 6874.2 3565.2 True False 3960.65929003697 3539.773760568308 10245.314635868317 7740.052960000787 8739.125367230648 10069.363572030741 6791.64531810491 10588.703572889537 7237.556178042555 3440.3834331624216 1.1512261255125007 1.028889316942945 2.9779572059067734 2.249764629544819 2.540160286493878 2.9268143413813967 1.9740954605928875 3.077768446046822 2.1037062637491393 1.0 11.748353647930973 -5.248535014378157 24.844646165910593 2.4399786765875904 1.0900574381438872 0.42531277439229853 0.5822861638834265 568.3245599067106 1094184.5592924359 0.13472954214007926 0.3514576389221711 5.642414483427488e-06 5.248535014378157 -1.3499212384437032 RIS(ph)HSLYSGIEGLDESPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RISHSLYSGIEGLDESPSR 19 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3;B1AP52 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 RIS(0.733)HS(0.257)LY(0.006)S(0.004)GIEGLDESPSR 62.556000000000004 0.006865100000000001 4084400.0 4053.2 5733.3 7126.7 6716.5 9698.6 6945.1 8016.3 6998.6 6339.4 5376.7 True False 4739.326705650925 6302.464133940312 7296.627556160256 6340.196280186799 7798.228951982638 6580.886729850202 7256.938031013898 6814.894165629649 6432.101732033485 6351.453148066221 0.7461799048449049 0.9922869596950702 1.1488123089409557 0.9982276704846907 1.2277865820921479 1.036123006253118 1.1425634200298498 1.0729661396785284 1.0126976586439622 1.0 12.632870988305525 -4.80626753349527 2.9394202522997936 1.085465139786835 0.6987210236361109 0.6642326664901912 0.07129222442655998 0.1998451749740021 2.5642986130496332 0.01705136232836641 0.18068463894831782 1.5621850110889376e-05 4.80626753349527 -0.386744116150724 RIS(ph)IVENCFGAAGQPLTIPGR ddPTM_PC-9_AZD4547_30min_R2 2 RISIVENCFGAAGQPLTIPGR 21 1 Q9H8W4 Q9H8W4 PLEKHF2 Pleckstrin homology domain-containing family F member 2 1 RIS(1)IVENCFGAAGQPLTIPGR;RIS(1)IVENCFGAAGQPLTIPGR 164.46 4.2305e-08 13497800.0 26840.9 24057.7 26726.3 39500.3 32767.3 24444.3 20633.9 28020.3 21879.0 21781.8 True False 35375.74787459764 31833.881051035176 26371.8917993458 30394.11610855146 28218.125999769112 22915.79405677226 22470.277126839126 23690.406477438253 23035.479273136247 21019.22581186393 1.6830185940830622 1.5145125389474197 1.2546557154574483 1.4460150140922907 1.3424912150590196 1.090230166509646 1.0690344795742275 1.1270827331835707 1.0959242495094315 1.0 14.35942191193452 -1.5228787452810375 0.23183820071810832 0.9792415278738669 4.978207621516874 0.859301728895556 0.0806748746842513 18.847740345894916 0.24768558173849384 0.1256383934402235 28.674417605308417 0.02999999999995165 1.5228787452810375 3.998966093643007 RIS(ph)IVENCFGAAGQPLTIPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RISIVENCFGAAGQPLTIPGR 21 1 Q9H8W4 Q9H8W4 PLEKHF2 Pleckstrin homology domain-containing family F member 2 1 RIS(1)IVENCFGAAGQPLTIPGR;RIS(1)IVENCFGAAGQPLTIPGR 78.343 0.00050962 18091400.0 39939.0 34380.0 36634.0 39356.0 40651.0 28587.0 28754.0 33841.0 27380.0 20625.3 True False 46699.88386879315 37793.0191904955 37507.49349521867 37151.010913873535 32685.728365645173 27087.847395462642 26030.212959067623 32952.70960750337 27780.380702129034 24364.503620215022 1.9167180500261312 1.551150796240271 1.539431875152138 1.5248006482286656 1.341530649470162 1.1117750567669307 1.0683662333046906 1.352488444712774 1.140198919508456 1.0 14.572493210249226 -1.5228787478350136 0.254275683870432 1.0400901579994428 6.513015689845115 0.8488700930054638 0.1050728842080327 20.09689174135672 0.2750813112390389 0.14280498666487393 47.30660916676865 0.029999999823529227 1.5228787478350136 5.4729255318456715 RIS(ph)IVENCFGAAGQPLTIPGR ddPTM_PC-9_Lapatinib_30min_R1 1 RISIVENCFGAAGQPLTIPGR 21 1 Q9H8W4 Q9H8W4 PLEKHF2 Pleckstrin homology domain-containing family F member 2 1 RIS(0.998)IVENCFGAAGQPLT(0.002)IPGR 52.185 0.04622 3596800.0 9881.1 8165.0 8854.7 8321.4 9687.8 8435.2 7139.6 5558.0 6832.6 7974.1 True False 9740.19370202819 8146.094444156103 8126.700746130451 8933.383515376636 9117.982650947626 8074.446159411597 7509.253553668906 5816.244970476561 6063.040637532291 9352.412560179637 1.0414632202496747 0.8710153013181058 0.8689416440771681 0.9551956201561159 0.974933750225032 0.8633543598996778 0.80292154621595 0.6218978186698861 0.6482862682242319 1.0 13.191122857110477 -7.251962621123028 2.463406256459739 0.7272867152487175 0.933175667694177 0.3481845875703625 0.10818387849894903 0.28779862078215557 3.4406004437496507 0.049087626028128585 0.03278406657061664 5.598057808108131e-08 7.251962621123028 0.20588895244545957 RIS(ph)LDQQ ddPTM_PC-9_AZD4547_30min_R2 1 RISLDQQ 7 1 Q96PM5-6;Q96PM5-2;Q96PM5;Q96PM5-8;Q96PM5-7 Q96PM5-6 RCHY1 RING finger and CHY zinc finger domain-containing protein 1 1 RIS(1)LDQQ 88.49600000000001 0.025314 16719000.0 76465.0 60790.0 85690.0 107190.0 101950.0 87390.0 69302.0 110080.0 78063.0 79693.0 True False 100779.27942919596 80439.17868675846 84553.69461114863 82479.00156899144 87796.00228509695 81925.4894851285 75469.74374423655 93069.66538675179 82189.25081122694 76902.97232666118 1.310473137515612 1.0459827007085827 1.099485391175642 1.0725073306483517 1.1416464101304873 1.0653097924113146 0.9813631575079218 1.2102219533390628 1.0687395860606168 1.0 16.2307517394799 -4.755903082156267 24.999752419461036 1.0820719635143237 1.310473499370952 0.5573078264220062 0.06245437184965853 134.01376911123646 605090.2016693469 0.014980214691358126 0.12734238277428694 1.7542719442654173e-05 4.755903082156267 0.22840153585662826 RIS(ph)LSDMPR ddPTM_PC-9_AZD4547_30min_R2 6 RISLSDMPR 9 1 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;A0A087WYS3;Q9ULU4-4;Q9ULU4-18;Q9ULU4-8;Q9ULU4-15;Q9ULU4-17;A0A087WV57 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 RIS(0.838)LS(0.162)DMPR;RIS(0.699)LS(0.301)DMPR;RIS(0.963)LS(0.037)DMPR;RIS(0.847)LS(0.153)DMPR;RIS(0.767)LS(0.233)DMPR;RIS(0.842)LS(0.158)DMPR 80.69 0.0083988 52353200.0 143839.19999999998 173332.90000000002 173595.69999999998 175515.6 166385.1 194827.99999999997 158920.80000000002 226598.90000000002 177084.7 136563.50000000003 True False 189577.07355877868 229359.37021539785 171293.70759258472 135053.19010898838 143285.40088088365 182645.37436100992 173064.44332961692 191583.2467297062 186445.0357164197 131782.45343169427 1.4385608146007132 1.7404393699065546 1.2998218133901263 1.0248192122101398 1.0872873979019644 1.3859612536025443 1.3132586230026442 1.4537841855327727 1.4147940857168684 1.0 17.00779876563041 -5.368896366012977 6.4635032618303905 1.2548856567826774 1.5870315363702794 0.4036325593589083 0.16671087270977802 0.23611835976028026 12.11472701780361 0.04617841012796726 0.09736809247541302 4.276649259785433e-06 5.368896366012977 0.332145879587602 RIS(ph)LSDMPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RISLSDMPR 9 1 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;A0A087WYS3;Q9ULU4-4;Q9ULU4-18;Q9ULU4-8;Q9ULU4-15;Q9ULU4-17;A0A087WV57 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 RIS(0.641)LS(0.359)DMPR;RIS(0.584)LS(0.416)DMPR 80.24 0.032951 3345600.0 76671.0 81580.0 89165.0 93725.0 111799.0 102619.0 142480.0 98156.0 125034.0 108404.0 True False 89649.88597872351 89678.72325656262 91291.03176014576 88473.89211054966 89892.7885058367 97237.47898957504 128983.2629341295 95579.50900487861 126862.3857089118 128056.78707440825 0.700079144783102 0.7003043361103086 0.7128949104985783 0.6908957668845878 0.7019759792474247 0.7593309281848104 1.00723488290537 0.7463837816682181 0.9906728773008928 1.0 16.966424192964574 -7.084072338484006 4.998426349786448 0.9140969069468123 0.7034330914611255 0.707420808711638 0.07111312420113354 0.1290074095217494 5.517985435277201 0.025972341625072143 0.02017272288106498 8.240008534553465e-08 7.084072338484006 -0.2106638154856868 RIS(ph)LSDMPR ddPTM_PC-9_Lapatinib_30min_R1 8 RISLSDMPR 9 1 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;A0A087WYS3;Q9ULU4-4;Q9ULU4-18;Q9ULU4-8;Q9ULU4-15;Q9ULU4-17;A0A087WV57 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 RIS(0.657)LS(0.343)DMPR;RIS(0.654)LS(0.346)DMPR;RIS(0.989)LS(0.011)DMPR;RIS(0.613)LS(0.387)DMPR;RIS(0.842)LS(0.158)DMPR;RIS(0.715)LS(0.285)DMPR;RIS(0.621)LS(0.379)DMPR;RIS(0.665)LS(0.335)DMPR 96.82 0.0022839 50907100.0 170754.8 173718.09999999998 166367.49999999997 135706.5 265240.5 343107.0 370747.0 327145.7 350855.5 283211.9 True False 168319.8052394045 173315.8664126578 152689.40634712158 145686.80871361302 249639.5752728871 328433.11343148194 389942.4655809966 342346.083526094 311338.4589177926 332164.69955886394 0.5067359820683655 0.5217768975536305 0.4596798110994423 0.43859810782751585 0.7515535985745159 0.9887658558168951 1.1739431255002872 1.0306516134337922 0.9373014631936207 1.0 18.34153923504168 -6.56338005064663 2.4876624603506934 1.0420638057375622 0.48319495729828343 0.9447692017585546 0.06200310050428297 0.06372845221334468 0.7986781124786227 0.02369884062991752 0.024748519482331845 2.732876142533206e-07 6.56338005064663 -0.5588688484392788 RIS(ph)LTK ddPTM_PC-9_Lapatinib_30min_R1 1 RISLTK 6 1 A0A0A0MRX4;Q3MIN7;Q3MIN7-2 A0A0A0MRX4 RGL3 Ral guanine nucleotide dissociation stimulator-like 3 1 RIS(1)LTK 59.35 0.044568 22608000.0 138770.0 117850.0 119290.0 110770.0 103110.0 114800.0 109780.0 118780.0 120500.0 89741.0 True False 136791.11435269864 117577.12556568233 109482.43667271631 118916.3953178875 97045.27252205966 109890.27161187053 115463.87124233475 124298.95242770905 106928.02107874617 105252.61227763376 1.2996457892358348 1.1170946071679357 1.0401873578579237 1.129818944580792 0.9220224602699181 1.0440621779723969 1.0970166796218406 1.1809583604427332 1.0159179783271606 1.0 16.683496514599923 -4.757247317426272 2.546083195274251 1.059376814924293 1.360541101681291 0.5416555176373967 0.06793971935563732 0.45329569051345203 3.565794172709264 0.018104629966641902 0.30724207145782106 1.748850488127376e-05 4.757247317426272 0.3011642867569979 RIS(ph)QSQPVR ddPTM_PC-9_AZD4547_30min_R2 1 RISQSQPVR 9 1 E7EMW7;O95071-2;O95071 E7EMW7 UBR5 E3 ubiquitin-protein ligase UBR5 1 RIS(0.5)QS(0.5)QPVR 87.719 0.015679 96009000.0 26527.0 21681.0 31036.0 49205.0 36474.0 36229.0 28484.0 42550.0 30939.0 35158.0 True False 34962.03420412324 28688.959254936814 30624.44236143783 37861.54745967184 31410.214687068485 33963.5949028118 31019.02081918036 35974.87520172864 32574.372376779636 33927.12912126234 1.0305037623184075 0.8456052721819385 0.9026535151848525 1.115966733416998 0.9258141051310914 1.0010748266208769 0.914283690444664 1.0603571871096797 0.9601275799184871 1.0 15.050151735394083 RIS(ph)QSQPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RISQSQPVR 9 1 E7EMW7;O95071-2;O95071 E7EMW7 UBR5 E3 ubiquitin-protein ligase UBR5 1 RIS(0.5)QS(0.5)QPVR;RIS(0.5)QS(0.5)QPVR;RIS(0.5)QS(0.5)QPVR;RIS(0.5)QS(0.5)QPVR 110.64 0.0015374 159385300.0 59202.200000000004 57901.9 80069.0 71883.8 100760.4 93907.0 84768.3 75386.3 91487.3 63663.5 True False 69223.96316325062 63650.017971673944 81978.14862337367 67856.38373642397 81017.12293458336 88982.35160617455 76738.43295465449 73407.4895033873 92825.12868553273 75205.18859001125 0.9204679153273866 0.8463514175686534 1.0900597440196034 0.9022832733835688 1.077281028789868 1.1831943151059816 1.0203874811484335 0.976096076343558 1.2342915485735748 1.0 16.198544579947697 -5.5153257047072675 0.8956010500396869 1.0796089705231313 0.8643802203857394 0.3299338969304211 0.09571876073991925 1.098369226808051 1.379174711077932 0.03789645878662452 0.18737273679763417 3.0526308949090636e-06 5.5153257047072675 -0.21522875013739196 RIS(ph)QSQPVR ddPTM_PC-9_Lapatinib_30min_R1 1 RISQSQPVR 9 1 E7EMW7;O95071-2;O95071 E7EMW7 UBR5 E3 ubiquitin-protein ligase UBR5 1 RIS(0.5)QS(0.5)QPVR 93.839 0.0087352 91439000.0 42651.0 33022.0 47682.0 37003.0 42656.0 46630.0 51158.0 44382.0 44821.0 38352.0 True False 42042.788918764505 32945.539587865635 43761.770017842704 39724.32405838944 40147.057944922664 44635.74359983911 53806.710921983526 46444.14974445675 39772.78699394591 44981.092099172245 0.9346769266088626 0.73243085150598 0.9728925638656963 0.8831338281162021 0.892531863308438 0.9923223629481532 1.1962073042458143 1.0325260587728466 0.8842112349397098 1.0 15.457031068387126 -6.8199220546482895 3.9443063469806128 1.0381750802734717 0.8785937484415751 0.36240046518566293 0.09169632124944042 0.23494565663748918 7.387209380796599 0.033748045681590254 0.030353686408658976 1.5138329204381085e-07 6.8199220546482895 -0.1595813318318966 RIS(ph)QVSSGETEYNPTEAR ddPTM_PC-9_AZD4547_30min_R2 3 RISQVSSGETEYNPTEAR 18 1 H7C3Y7;H0Y764;A0A494C1V1;Q6ZNJ1-2;Q6ZNJ1-3;Q6ZNJ1 H7C3Y7 NBEAL2 Neurobeachin-like protein 2 1 RIS(0.955)QVS(0.044)SGETEYNPTEAR;RIS(0.993)QVS(0.006)S(0.001)GETEYNPTEAR;RIS(1)QVSSGETEYNPTEAR 223.76 1.2334e-34 46994000.0 45876.0 50488.0 61265.0 81590.0 76113.0 63365.0 67496.0 93436.0 74873.0 63363.0 True False 60463.613719921515 66807.25865334859 60452.58607016015 62780.68605293408 65546.02375601369 59402.77653307217 73503.01324292214 78997.61314568087 78830.63392374104 61144.68065619619 0.9888613869765029 1.0926094949942071 0.9886810335975496 1.026756299635234 1.0719824366172641 0.9715117635020716 1.2021162340549996 1.2919785056997517 1.2892476185621 1.0 15.899939375035899 -7.321573560038336 6.672957791493216 1.2218148830416622 1.027464171855655 0.4905683393122453 0.08444352897627654 0.1829773098365173 16.750225055966457 0.033653357495580946 0.022640922015788958 4.768990309557606e-08 7.321573560038336 -0.19435071118600722 RIS(ph)QVSSGETEYNPTEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RISQVSSGETEYNPTEAR 18 1 H7C3Y7;H0Y764;A0A494C1V1;Q6ZNJ1-2;Q6ZNJ1-3;Q6ZNJ1 H7C3Y7 NBEAL2 Neurobeachin-like protein 2 1 RIS(0.998)QVS(0.002)SGETEYNPTEAR;RIS(0.999)QVS(0.001)SGETEYNPTEAR;RIS(0.992)QVS(0.008)SGETEYNPTEAR;RIS(1)QVSSGETEYNPTEAR 195.45 2.5059e-14 52859300.0 56560.0 60188.0 69094.0 63647.0 64691.0 64070.0 56689.8 66359.0 62210.0 49449.5 True False 66134.49088907933 66163.06687136544 70741.46300045415 60081.064936358096 52015.26293822916 60710.05641121111 51319.73174539023 64617.146563172326 63119.70356024276 58414.30290797338 1.132162631355345 1.1326518263104082 1.2110298245260434 1.028533457482332 0.8904542269412109 1.0393012222854818 0.878547362385544 1.1061870697142613 1.0805522007115675 1.0 15.834034039886944 -5.8761389559181785 5.948758775631541 0.9971268804274876 1.1550196768343801 0.5032523908164864 0.07101715593565437 0.1748304242416168 8.423434099397701 0.020607027668386367 0.030967074045965215 1.3300287967692633e-06 5.8761389559181785 0.15789279640689247 RIS(ph)QVSSGETEYNPTEAR ddPTM_PC-9_Lapatinib_30min_R1 4 RISQVSSGETEYNPTEAR 18 1 H7C3Y7;H0Y764;A0A494C1V1;Q6ZNJ1-2;Q6ZNJ1-3;Q6ZNJ1 H7C3Y7 NBEAL2 Neurobeachin-like protein 2 1 RIS(1)QVSSGETEYNPTEAR;RIS(0.99)QVS(0.01)SGETEYNPTEAR;RIS(0.99)QVS(0.008)S(0.001)GETEYNPTEAR;RIS(1)QVSSGETEYNPTEAR 219.23 1.3271e-27 44087700.0 128400.0 114591.0 120648.0 108214.3 113237.0 102396.6 110636.0 101866.0 133732.0 96991.7 True False 126568.99245432366 114325.67157994982 110728.78715474787 116172.74061432263 106576.62229250773 98017.33611613297 116364.1907338944 106599.06624011626 118669.69389960912 113756.58611168365 1.1126300180110986 1.0050026595181702 0.97338352828237 1.021239688929016 0.936883093413802 0.861640978043256 1.0229226694588978 0.9370803914197962 1.0431896557013578 1.0 16.795590549203972 -3.1561007721309076 1.0372561192331324 0.9674542623433598 4.942347631700673 0.3970991932909572 0.05068293392589715 45.9371279804049 2.308839768961216 0.015870677685726278 393.9595825448775 0.0006980704075345601 3.1561007721309076 3.974893369357313 RIS(ph)SSSVQPCSEEVSTPQDSLAQCK ddPTM_PC-9_AZD4547_30min_R2 1 RISSSSVQPCSEEVSTPQDSLAQCK 25 1 J3QS41;P42694 J3QS41 HELZ Probable helicase with zinc finger domain 1 RIS(0.434)S(0.132)S(0.202)S(0.202)VQPCS(0.029)EEVSTPQDSLAQCK 134.98 2.5495e-07 39940000.0 88660.0 72391.0 105240.0 141560.0 121150.0 104800.0 93381.0 131260.0 103050.0 106060.0 True False 116852.03575743808 95789.97506683877 103844.44883740557 108925.52908019804 104330.41370122152 98246.83943290399 101691.72809703276 110976.78305473321 108497.0126192554 102346.87168215134 1.1417255245508042 0.9359345673439274 1.0146323686365823 1.0642780506127965 1.0193805827815654 0.9599398381029132 0.9935987922801081 1.0843202262144656 1.0600911472526875 1.0 16.64310748028987 -10.647351047085138 4.675191896927324 0.9999978792226699 1.0262878740972483 0.020099958712514132 0.05753037397313101 1.255477139749547e-06 2.350710416925977e-07 0.05499391563530537 0.013336907666122055 2.252417811246403e-11 10.647351047085138 0.026289994874578393 RIS(ph)SSSVQPCSEEVSTPQDSLAQCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RISSSSVQPCSEEVSTPQDSLAQCK 25 1 J3QS41;P42694 J3QS41 HELZ Probable helicase with zinc finger domain 1 RIS(0.2)S(0.2)S(0.2)S(0.2)VQPCS(0.2)EEVS(0.001)T(0.001)PQDSLAQCK 57.147 0.0023745000000000003 21803000.0 23982.0 26205.0 20517.0 27415.0 20917.0 26832.0 23147.0 24422.0 21570.0 12651.0 True False 28041.67893390914 28806.459217188316 21006.203091155807 25879.02643062922 16818.464003940873 25424.882684963588 20954.348590232246 23780.948377247936 21885.42044356915 14944.526154739111 1.8763846135741644 1.9275592226156597 1.4056118523700705 1.7316725978911436 1.1253929251284767 1.7012839632189352 1.4021420534358888 1.5912815254906343 1.464443918593497 1.0 13.867329533839088 -1.522878745280492 0.04615230170821729 1.4839600600755842e-12 4.232762530055488 0.5036638565359753 0.20320903072516106 514.7062265238864 1.8063506519775905 41.410825257571275 160.25978126281538 0.029999999999989337 1.522878745280492 4.2327625300540035 RIS(ph)TSDILSEK ddPTM_PC-9_AZD4547_30min_R2 4 RISTSDILSEK 11 1 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 RIS(0.799)T(0.197)S(0.003)DILSEK;RIS(0.749)T(0.198)S(0.053)DILSEK;RIS(0.988)T(0.01)S(0.003)DILSEK;RIS(0.87)T(0.114)S(0.016)DILSEK 124.2 0.00024008 23309700.0 137992.0 143840.0 166557.0 229393.0 194118.0 181050.0 143442.0 183731.0 152721.0 145771.0 True False 181870.58558809382 190333.4670554918 164348.34535358936 176509.98793652048 167168.06642058355 169728.91487907706 156208.06011602574 155339.59566836208 160793.52027389893 140667.60165923924 1.2929102610895926 1.353072525659219 1.168345400184725 1.2548020002794087 1.1883906773753097 1.2065956401975027 1.1104764584984717 1.1043025816610215 1.1430742998193273 1.0 17.10193056201777 -1.522878745288775 0.10254862543704532 0.8969908491143551 2.167885169473248 0.8087599987900795 0.0422837323229532 48.584282766847714 0.3531152435791421 0.4818230468998721 8.694905181920904 0.029999999999417156 1.522878745288775 1.270894320358893 RIS(ph)TSDILSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RISTSDILSEK 11 1 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 RIS(0.879)T(0.118)S(0.003)DILSEK;RIS(0.68)T(0.106)S(0.214)DILSEK 118.2 0.00049828 11988700.0 54579.0 65262.0 41954.0 60150.0 78805.0 83188.0 100483.0 90207.0 82790.0 75650.0 True False 63818.14671561285 71740.78005846759 42954.342471431024 56779.99050893113 63363.725956425886 78825.47483589558 90964.52280607898 87839.16183221716 84000.64712670793 89364.74615492967 0.7141311250968335 0.8027861449311587 0.4806631733386456 0.6353734884502769 0.7090461136271076 0.8820645526059864 1.0179016527208147 0.9829285664833911 0.9399752222322423 1.0 16.447418188830262 -6.830205184842421 2.5174587586728117 0.9828100319276092 0.6568293290889131 0.7917974501260272 0.07760793049306058 0.13390285544156277 1.732755988795246 0.03201148928976028 0.02841842675626489 1.4784097402402084e-07 6.830205184842421 -0.32598070283869607 RIS(ph)TSDILSEK ddPTM_PC-9_Lapatinib_30min_R1 2 RISTSDILSEK 11 1 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 RIS(0.87)T(0.127)S(0.003)DILSEK;RIS(0.464)T(0.464)S(0.072)DILSEK 101.2 0.0017569000000000003 17599500.0 64604.0 46892.0 60173.0 56461.0 95081.0 116852.0 128338.0 131390.0 116353.0 113734.0 True False 63682.73511307742 46783.42445503587 55225.80821449708 60613.33028837464 89488.52251643826 111854.5123553164 134982.7136773431 137494.85906277713 103248.09988859217 133392.7703589712 0.4774076956472364 0.35071934055449727 0.41400900562961374 0.4543974169309105 0.6708648622831439 0.8385350424487509 1.011919261546883 1.0307519567422347 0.7740157102273446 1.0 17.02532095167968 -6.564814262378864 1.6274935982517615 0.9564475697320833 0.40581891495029865 0.9131762562138588 0.07429924160058618 0.09734788864072148 0.5272735722923979 0.029557691398391366 0.03139158417862207 2.723865992964077e-07 6.564814262378864 -0.5506286547817847 down RISACLSDYS(ph)LASDSGVFEPLTK ddPTM_PC-9_Lapatinib_30min_R1 1 RISACLSDYSLASDSGVFEPLTK 23 1 Q9ULE0 Q9ULE0 WWC3 Protein WWC3 1 RIS(0.064)ACLS(0.064)DY(0.068)S(0.612)LAS(0.09)DS(0.101)GVFEPLT(0.001)K 52.122 0.009898200000000001 2391700.0 9740.4 8745.9 11772.0 9117.2 9954.0 10654.0 10479.0 9549.1 13570.0 10466.0 True False 9601.500109829401 8725.649405896489 10804.151601234105 9787.709302087615 9368.525290316964 10198.353255687018 11021.551345859207 9992.786046703432 12041.603701565029 12275.03415493161 0.7821974251674003 0.7108452241976758 0.8801728341336985 0.7973671745878858 0.7632178592800958 0.8308207640782599 0.8978835583468576 0.814073991206675 0.9809833153683896 1.0 13.58343941835271 -8.078332640328327 0.576459056311515 1.0085131331677468 0.7795719163607164 0.6669351807901986 0.05116560255364295 0.4740075576211776 0.3662812894818864 0.0510648317333088 0.02648936396995919 8.34963247629552e-09 8.078332640328327 -0.2289412168070304 RISHS(ph)LYSGIEGLDESPSR ddPTM_PC-9_Lapatinib_30min_R1 1 RISHSLYSGIEGLDESPSR 19 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3;B1AP52 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 RIS(0.343)HS(0.492)LY(0.151)S(0.014)GIEGLDESPSR 52.731 0.019928 5292400.0 7149.9 6458.6 8014.4 7864.6 6567.5 10049.0 6880.4 5873.7 8361.1 8581.4 True False 7047.94111486892 6443.645508515205 7355.4869684786445 8442.988919536507 6181.212562201792 9619.227695363134 7236.633445944246 6146.613544996072 7419.384871713739 10064.68355600325 0.7002645513544294 0.6402233585050753 0.7308214836115081 0.8388727646087336 0.6141487238826205 0.9557406988345484 0.7190125159601102 0.6107110582060795 0.7371702081272413 1.0 13.297014192706698 -11.737750147268317 2.140244828517111 1.7844814417173873 0.7279537175186209 0.4018326883688913 0.09976160635752972 9453374.003195832 1621353.2517118468 35917317.55889165 0.024772945277937625 1.8291522379032895e-12 11.737750147268317 -1.0565277241987663 RISSSSVQPCS(ph)EEVSTPQDSLAQCK ddPTM_PC-9_AZD4547_30min_R2 1 RISSSSVQPCSEEVSTPQDSLAQCK 25 1 J3QS41;P42694 J3QS41 HELZ Probable helicase with zinc finger domain 1 RIS(0.065)S(0.073)S(0.082)S(0.082)VQPCS(0.662)EEVS(0.018)T(0.018)PQDSLAQCK 58.516000000000005 0.0019928 37558000.0 25571.0 26727.0 37474.0 46181.0 44137.0 38908.0 30613.0 44538.0 40765.0 41004.0 True False 33702.04609015855 35365.98007502869 36977.07027492339 35534.68393933758 38009.339410076784 36475.07660930751 33337.49769476088 37655.675481423976 42919.75467660309 39568.462440646275 0.8517400983349427 0.8937921236661288 0.9345086463844775 0.8980557177990054 0.9605968254918114 0.9218219349316662 0.8425269934298811 0.9516587999321042 1.0846960440018067 1.0 15.27206338541219 -8.059618174212495 5.325593875050381 1.0384474773681225 0.9039226745205577 0.6802635329272382 0.0384656133732742 0.1258097665281283 7.311117380131296 0.026604151099906555 0.00993300446571604 8.717296659824787e-09 8.059618174212495 -0.13452480284756474 RISSSSVQPCS(ph)EEVSTPQDSLAQCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RISSSSVQPCSEEVSTPQDSLAQCK 25 1 J3QS41;P42694 J3QS41 HELZ Probable helicase with zinc finger domain 1 RIS(0.136)S(0.164)S(0.2)S(0.2)VQPCS(0.298)EEVS(0.002)T(0.001)PQDSLAQCK 75.717 7.3886e-05 26780000.0 75926.0 70969.0 84929.0 82823.0 88679.0 79144.0 77357.0 84898.0 86433.0 73330.0 True False 88778.77219314434 78014.33330221874 86954.0294550259 78182.69582578873 71302.98653752792 74993.54931495075 70029.1849438197 82669.51745686651 87696.91910982881 86624.14852003935 1.0248732450467497 0.9006072167528568 1.0038081867541848 0.9025508147731137 0.8231305906693318 0.8657349087547105 0.808425665824806 0.9543472446109182 1.0123841978030097 1.0 16.402481645766642 -11.082123159406859 4.461081838657449 1.0009071921236314 0.9160644365031848 0.08890912387698524 0.07311552637495466 0.0007041765183298096 6.957274872783913e-05 0.07556593390337286 0.018132991532619453 8.27707405010601e-12 11.082123159406859 -0.08484275562044663 RISSSSVQPCS(ph)EEVSTPQDSLAQCK ddPTM_PC-9_Lapatinib_30min_R1 2 RISSSSVQPCSEEVSTPQDSLAQCK 25 1 J3QS41;P42694 J3QS41 HELZ Probable helicase with zinc finger domain 1 RIS(0.014)S(0.014)S(0.014)S(0.02)VQPCS(0.937)EEVSTPQDSLAQCK;RIS(0.036)S(0.01)S(0.004)S(0.014)VQPCS(0.935)EEVS(0.001)TPQDSLAQCK 94.259 1.3244e-06 74984000.0 120712.0 125332.0 150551.0 133620.0 168464.0 150378.0 137449.0 135757.0 159293.0 142147.0 True False 118990.62474413036 125041.80145437515 138173.27792366588 143446.86054325337 158555.27873296742 143946.68348823953 144565.43667687787 142064.76582529448 141351.74491034632 166716.91955102832 0.7137285469559674 0.7500246633102086 0.8287897730822343 0.8604217312169536 0.9510449158967167 0.8634197649278224 0.8671311650082979 0.8521316625083852 0.8478548265587508 1.0 17.34704100055891 -5.3394244161519815 1.649288099058286 0.8868846081412086 0.710820199061207 0.6620783709070686 0.04584504118040847 0.27883369547948644 1.3323282858084895 0.013352943554058666 0.054694495741969024 4.576943842809968e-06 5.3394244161519815 -0.17606440908000165 RIT(ph)S(ph)PLMEPS(ph)S(ph)IEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RITSPLMEPSSIEK 14 1 P28066 P28066 PSMA5 Proteasome subunit alpha type-5 4 RIT(1)S(1)PLMEPS(1)S(1)IEK 53.327 0.039055 0.0 5766.0 5136.8 4076.0 6460.5 8326.2 5808.6 9636.7 8977.4 9116.8 6840.0 True False 6742.0699163088975 5646.7475560714765 4173.187298316081 6098.539130223599 6694.740880126811 5503.986790544109 8723.842012333827 8741.75276234156 9250.115952708915 8080.037854589796 0.8344106844102374 0.698851621451735 0.5164811568234842 0.7547661582747879 0.8285531578696653 0.6811832926522264 1.079678359103024 1.0818950256991535 1.1448109673712068 1.0 12.980146336612059 -7.2650753503691075 24.812193314048304 1.0834207001429963 0.7155177355650435 0.792499008359697 0.08959311813934205 131.27632314828944 895835.0389374099 0.03841357141371902 0.027047089370510303 5.4315608539017015e-08 7.2650753503691075 -0.3679029645779528 RITS(ph)PLMEPSSIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RITSPLMEPSSIEK 14 1 P28066 P28066 PSMA5 Proteasome subunit alpha type-5 1 RIT(0.332)S(0.668)PLMEPSSIEK 66.215 0.030498 0.0 14540.0 14952.0 16170.0 25659.0 22068.0 22361.0 19599.0 20195.0 23471.0 15110.0 True False 17001.334821909706 16436.335745674485 16555.554125066486 24221.409417600385 17743.9338164635 21188.34979570925 17742.44083552779 19664.902648371222 23814.21897223049 17849.323389305817 0.9524918368668153 0.9208380277048538 0.9275171816868714 1.3569931413821725 0.9940955984412575 1.1870673937368386 0.9940119548821629 1.1017169793759904 1.3341804870036957 1.0 14.12358176689099 -5.636477334117254 20.334520569930312 1.1333324596739098 0.9321527442171377 0.36702626225210644 0.12304426443626014 2.4811444220396934 430.97895515557525 0.03194855525124332 0.05533653257944425 2.309524990168968e-06 5.636477334117254 -0.20117971545677216 RKADTTTPTPTAILAPGS(ph)PASPPGSLEPK ddPTM_PC-9_AZD4547_30min_R2 2 RKADTTTPTPTAILAPGSPASPPGSLEPK 29 2 H0Y6K2;A0A140T9E9;A0A0G2JK44;P25440-4;P25440-3;P25440;P25440-2;H0YDJ7;U3KPW0;E9PIQ3;U3KQA6;A0A0G2JHL0;A0A140T9F7;A0A140T9V2 H0Y6K2 BRD2 Bromodomain-containing protein 2 1 RKADTTTPTPTAILAPGS(0.653)PAS(0.176)PPGS(0.171)LEPK;RKADTTTPTPTAILAPGS(0.99)PAS(0.01)PPGSLEPK 104.6 3.5999e-05 11215000.0 23570.0 24391.0 29730.0 40195.0 31889.0 33658.0 26274.0 26513.0 26544.0 29195.0 True False 31064.76971354411 32274.91375799844 29335.760774763097 30928.663756559465 27461.762794207545 31553.359939243157 28612.335100517663 22416.025058130006 27947.061649349987 28172.89193626638 1.1026475302507044 1.1456017305930746 1.0412761615359685 1.0978164338445369 0.9747583903112406 1.1199900958206273 1.0155980850402366 0.7956593561229091 0.9919841283093239 1.0 14.782020042941609 -7.531150620597739 24.88076457976951 0.9174187424117601 1.0767213363768795 0.49337126003979714 0.06825809602935143 138.4039538934468 416294.74184231 0.03055671867522471 0.017679546756214054 2.9434006361373335e-08 7.531150620597739 0.15930259396511937 RKADTTTPTPTAILAPGSPAS(ph)PPGSLEPK ddPTM_PC-9_AZD4547_30min_R2 1 RKADTTTPTPTAILAPGSPASPPGSLEPK 29 2 H0Y6K2;A0A140T9E9;A0A0G2JK44;P25440-4;P25440-3;P25440;P25440-2;H0YDJ7;U3KPW0;E9PIQ3;U3KQA6;A0A0G2JHL0;A0A140T9F7;A0A140T9V2 H0Y6K2 BRD2 Bromodomain-containing protein 2 1 RKADTTTPTPTAILAPGS(0.018)PAS(0.975)PPGS(0.007)LEPK 104.89 9.7814e-12 8980000.0 63987.0 47741.0 68090.0 98006.0 90418.0 78282.0 60347.0 71146.0 58712.0 74971.0 True False 84333.5349877195 63172.34462386137 67187.0821107844 75412.23087760594 77865.02142828747 73387.0141649483 65717.76609237048 60152.02047243683 61815.3964570764 72346.28810939641 1.1656926318071343 0.8731939989559254 0.9286873434223651 1.0423787155959328 1.076282190325315 1.0143853414286879 0.9083778561382059 0.8314458425493737 0.8544377061004703 1.0 16.142631377459978 -7.333664285365278 4.276447037878656 0.8808243514417134 1.010256801982171 0.31002764977351116 0.08516648987327197 0.2786021594854509 9.826966427954739 0.037534558697160304 0.024917651673817945 4.6380530804239644e-08 7.333664285365278 0.1294324505404575 RKADTTTPTPTAILAPGSPAS(ph)PPGSLEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RKADTTTPTPTAILAPGSPASPPGSLEPK 29 2 H0Y6K2;A0A140T9E9;A0A0G2JK44;P25440-4;P25440-3;P25440;P25440-2;H0YDJ7;U3KPW0;E9PIQ3;U3KQA6;A0A0G2JHL0;A0A140T9F7;A0A140T9V2 H0Y6K2 BRD2 Bromodomain-containing protein 2 1 RKADTTTPTPTAILAPGS(0.159)PAS(0.779)PPGS(0.062)LEPK;RKADTTTPTPTAILAPGS(0.009)PAS(0.898)PPGS(0.093)LEPK 101.71 1.9577000000000002e-11 16819100.0 63406.0 40630.0 55420.0 72207.0 77513.0 78977.0 68577.0 68219.0 68314.0 53817.0 True False 74139.3834744159 44663.47788568447 56741.42298152043 68161.47588825242 62324.88408172621 74835.30708893735 62080.890105515115 66428.32353400513 69312.96301260921 63573.59608486243 1.1661977305082682 0.7025476083823318 0.8925312783278463 1.0721664352173153 0.9803580089842746 1.1771444703087428 0.9765200323518785 1.0449042939985966 1.0902790982609427 1.0 15.956140077341423 -5.757765345484162 24.956002854173665 1.050126832201306 0.8986377062659509 0.1902225343525803 0.11879984971937696 124.79810780636048 847678.8861097811 0.030982667092491433 0.051113958501193206 1.7467656964434192e-06 5.757765345484162 -0.15148912593535513 RKADTTTPTPTAILAPGSPAS(ph)PPGSLEPK ddPTM_PC-9_Lapatinib_30min_R1 1 RKADTTTPTPTAILAPGSPASPPGSLEPK 29 2 H0Y6K2;A0A140T9E9;A0A0G2JK44;P25440-4;P25440-3;P25440;P25440-2;H0YDJ7;U3KPW0;E9PIQ3;U3KQA6;A0A0G2JHL0;A0A140T9F7;A0A140T9V2 H0Y6K2 BRD2 Bromodomain-containing protein 2 1 RKADTTTPTPTAILAPGS(0.055)PAS(0.902)PPGS(0.044)LEPK 81.904 4.2802e-07 7036000.0 36847.0 17710.0 20498.0 24247.0 23401.0 18227.0 14817.0 13607.0 21098.0 15361.0 True False 36321.55502308778 17668.99358309915 18812.733564568185 26030.20526562087 22024.599188136133 17447.47369921224 15584.151759862198 14239.230894795703 18721.721068210678 18016.128382754086 2.016057737346973 0.9807319978921092 1.0442162247565159 1.4448279182190025 1.2224934636466707 0.9684363548338061 0.865011140505643 0.7903602034955627 1.0391645014104152 1.0 14.137001392747566 -6.729071315458778 3.0776201434995007 0.9071368381589896 1.322039646364158 0.36733733935551793 0.2707554145004406 0.3007992176990888 5.852536083135131 0.09759195950211863 0.09254947807750619 1.8660732379513434e-07 6.729071315458778 0.41490280820516834 RKAS(ph)PEPEGEAAGK ddPTM_PC-9_AZD4547_30min_R2 3 RKASPEPEGEAAGK 14 2 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 RKAS(1)PEPEGEAAGK;RKAS(1)PEPEGEAAGK;RKAS(1)PEPEGEAAGK 81.71300000000001 0.014536000000000002 49777000.0 206317.0 179468.0 214597.0 307519.0 282047.0 251235.0 213871.0 237949.0 190490.0 233071.0 True False 271921.5143398077 237477.52131197855 211751.3035648112 236625.24567118855 242889.6425356035 235525.23573402292 232905.104676974 201179.44957405684 200558.9125069575 224911.25523129126 1.2090169256321683 1.0558721086135265 0.9414882476515157 1.0520827222623919 1.0799354718189798 1.0471918601486465 1.035542238370695 0.8944836903211917 0.8917246595805505 1.0 17.778996334129978 -7.685175667646698 5.24365747579854 0.9201141909535173 1.0568772980439898 0.4453877008839342 0.06718389559825393 0.18916199884827306 9.13654982057007 0.03401532643155301 0.018886985096860515 2.064544899739031e-08 7.685175667646698 0.13676310709047246 RKAS(ph)PEPEGEAAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RKASPEPEGEAAGK 14 2 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 RKAS(1)PEPEGEAAGK;RKAS(1)PEPEGEAAGK 67.994 0.010562 17543500.0 187868.0 149623.0 176444.0 232629.0 225428.0 214987.0 227783.0 208035.0 199249.0 187548.0 True False 219670.3418378637 164476.58261604176 180651.09412759653 219595.55132339345 181257.00164843796 203712.70325701643 206205.7452338908 202574.30168130307 202162.6396829253 221548.96777084866 0.99152049340655 0.7423938114943613 0.8154002970325125 0.9911829133436737 0.8181351665601744 0.91949290175759 0.9307456825850456 0.9143545272159816 0.9124964188143954 1.0 17.75726607954843 -8.529910083284499 0.2553240017626796 1.0230337050767353 0.8435157477015993 0.18676322056101968 0.07378704793522152 4.292382274499852 0.919738581951053 0.277980129691413 0.16607541941463863 2.9518203109050164e-09 8.529910083284499 -0.17951795737513598 RKAS(ph)PEPEGEAAGK ddPTM_PC-9_Lapatinib_30min_R1 1 RKASPEPEGEAAGK 14 2 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 RKAS(1)PEPEGEAAGK 43.593999999999994 0.045805 3561200.0 35003.0 28561.0 30593.0 25934.0 28484.0 27335.0 25840.0 24902.0 26859.0 23415.0 True False 34503.850801235945 28494.86875928261 28077.76163239507 27841.27287328788 26808.62712169864 26165.945770997234 27177.868763908977 26059.03782922044 23833.856582191238 27462.251551473688 1.2564101212372876 1.0376013308986498 1.0224129503645287 1.0138015384901626 0.9761991682091349 0.9527968135443399 0.9896445931597532 0.948903908347677 0.867877003366545 1.0 14.745162292324421 -1.5228787453157882 0.7169165181041035 0.9564571855830644 41.383811535246736 0.8363207234184422 0.03846444815931791 119.83029400103545 0.5940680144572896 0.014975607531249314 7786.749058791427 0.02999999999755116 1.5228787453157882 40.42735434966367 RKAS(ph)PEPPDSAEGALK ddPTM_PC-9_AZD4547_30min_R2 4 RKASPEPPDSAEGALK 16 2 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 RKAS(0.999)PEPPDS(0.001)AEGALK;RKAS(0.996)PEPPDS(0.004)AEGALK;RKAS(1)PEPPDSAEGALK;RKAS(0.846)PEPPDS(0.154)AEGALK 65.265 0.009194299999999999 92244000.0 281346.0 247410.0 309492.0 428340.0 382455.0 373960.0 306024.0 362203.0 333901.0 358458.0 True False 370808.17563965905 327380.44413375366 305387.9338615198 329592.8307870305 329357.7249038431 350576.2220832895 333259.5431529581 306232.8489469263 351550.32518759795 345908.49452612357 1.071983433502108 0.9464365556626403 0.8828575727227664 0.9528324282367086 0.9521527517126916 1.0134941108155222 0.9634326662301431 0.8853001698222218 1.0163101824637275 1.0 18.40003091705843 RKAS(ph)PEPPDSAEGALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RKASPEPPDSAEGALK 16 2 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 RKAS(0.992)PEPPDS(0.008)AEGALK 76.01 0.0037830999999999997 31357000.0 33767.0 35027.0 36130.0 41704.0 50394.0 45336.0 43385.0 43954.0 42147.0 36691.0 True False 39483.086171349736 38504.249074621475 36991.476223788035 39367.46008619225 40519.6574563559 42958.50035053326 39275.25871980067 42800.25407311259 42763.32014070971 43342.78785420382 0.9109493903383112 0.888365769274967 0.8534632416405634 0.9082816781102371 0.9348650481979989 0.9911337612854247 0.9061544183986162 0.9874827207027799 0.9866305851058006 1.0 15.403504331644658 -6.346234437963821 2.224080565839805 0.9693311069393189 0.8848308865875643 0.657238714581059 0.02850977694472692 0.201307328430932 1.954087799420438 0.009866666049240063 0.011939180817505014 4.505734133329408e-07 6.346234437963821 -0.08450022035175464 RKAS(ph)PEPPDSAEGALK ddPTM_PC-9_Lapatinib_30min_R1 2 RKASPEPPDSAEGALK 16 2 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 RKAS(1)PEPPDSAEGALK;RKAS(0.998)PEPPDS(0.002)AEGALK 64.407 0.0096723 54003000.0 219090.0 175635.0 185675.0 170203.0 193455.0 194119.0 155290.0 159707.0 186235.0 164840.0 True False 215965.73642381513 175228.32794848218 170409.51822622673 182720.2964005634 182076.3572471637 185816.98288349065 163330.15636019455 167127.57025906813 165259.25315850874 193332.37436450607 1.1170696947870533 0.9063579161248453 0.8814329146185268 0.9451096692996963 0.9417789330196688 0.9611270926262665 0.8448153440264186 0.8644572374824726 0.8547934804076389 1.0 17.56072371790585 -4.761258642820153 24.999936799810236 0.9074480784436558 1.1170699260752264 0.6206344003132491 0.048234690799013435 2.880706455176962 397400.6594455399 0.012307903099134399 0.0692662598493242 1.7327717432162837e-05 4.761258642820153 0.20962184763157055 RKASPEPPDS(ph)AEGALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RKASPEPPDSAEGALK 16 2 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 RKAS(0.159)PEPPDS(0.841)AEGALK 55.413999999999994 0.020997 16918000.0 60858.0 48299.0 54121.0 81180.0 78253.0 65528.0 70162.0 69924.0 57725.0 57836.0 True False 71160.05739970996 53093.805523029114 55411.44989503547 76631.74778911115 62919.88639386078 62091.59632454877 63515.74743110878 68088.56909060216 58569.11892002913 68321.2089704759 1.0415514958240981 0.7771204040896421 0.8110431699032257 1.1216392236593258 0.9209422277795285 0.908818758628537 0.929663692844725 0.9965949097889315 0.8572611609571925 1.0 16.06004588378593 RKASPEPPDS(ph)AEGALK ddPTM_PC-9_Lapatinib_30min_R1 1 RKASPEPPDSAEGALK 16 2 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 RKAS(0.184)PEPPDS(0.816)AEGALK 52.008 0.026924 43733000.0 121330.0 115080.0 114740.0 113660.0 111450.0 117300.0 101520.0 109710.0 116620.0 98636.0 True False 119599.81195080304 114813.53933049408 105306.5201092085 122018.9355586451 104894.7301191305 112283.35243965524 106776.20885882496 114807.52711604576 103485.02753695751 115685.10117579147 1.033839368555013 0.9924660839084802 0.9102859317137822 1.0547506491197076 0.9067263550190076 0.970594755058674 0.9229901497563733 0.9924141133920765 0.8945406667337819 1.0 16.819843549393426 -4.982067241407791 4.955814811026579 0.9568403982016581 1.0273096297995805 0.20656888082365144 0.04763060070098525 0.2585540769290087 17.75386000858879 0.011122442586584643 0.04378420038384451 1.0421560608547335e-05 4.982067241407791 0.0704692315979224 RKDS(ph)AQDDQAK ddPTM_PC-9_Lapatinib_30min_R1 1 RKDSAQDDQAK 11 2 Q13045-2;Q13045-3;Q13045;J3KS54 Q13045-2 FLII Protein flightless-1 homolog 1 RKDS(1)AQDDQAK 55.806000000000004 0.026619 800870.0 7128.8 3867.6 8379.5 6855.6 6314.9 5484.7 9920.8 5982.3 5212.3 4006.9 True False 7027.142004738188 3858.6448098246365 7690.569855805401 7359.783693611184 5943.46999757108 5250.132166460162 10434.450481152786 6260.259497459866 4625.23588604771 4699.487326141359 1.495299703363178 0.8210778202040352 1.6364699640800928 1.566082251711089 1.2647060381480222 1.1171712576509756 2.220338040515639 1.332115412384785 0.9842000978105382 1.0 12.198287664351138 -8.205935179306712 5.003525552251833 0.9897005451378617 1.4361004354308444 0.2092698359005284 0.34495230389170706 0.31933373012473604 17.036699816378174 0.2613637579768611 0.09029351560547767 6.223931736309553e-09 8.205935179306712 0.44639989029298277 RKEDEVEEWQHR ddPTM_PC-9_AZD4547_30min_R2 5 RKEDEVEEWQHR 12 2 P15311;E7EQR4 P15311 EZR Ezrin 0 ;;;; 98.156 0.00095694 408906000.0 173011.0 170570.0 232672.0 262071.0 233019.0 250866.0 223545.0 234001.0 215280.0 225626.0 False True 228024.8991476449 225703.41682185227 229586.6172548159 201654.5799065878 200668.33405072143 235179.3093623553 243440.0719359526 197841.52225804288 226659.26129716946 217726.9024152094 1.0472977689858327 1.036635410315219 1.0544705992141927 0.9261812742002302 0.9216515360515397 1.0801573289912692 1.1180982654670193 0.9086682447755368 1.0410255176685785 1.0 17.732160152900462 RKEDEVEEWQHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RKEDEVEEWQHR 12 2 P15311;E7EQR4 P15311 EZR Ezrin 0 ;;; 121.02 0.00011902 80967200.0 127274.0 143941.0 159818.0 158644.0 170183.0 136585.6 161071.0 163780.0 130300.0 120896.1 False True 148818.97442391588 158230.51120707137 163628.6672331399 149755.69101078744 136836.8628188875 129422.81069079321 145813.18882694506 159480.94853925396 132205.3909966185 142813.60591699867 1.0420503947670605 1.1079512360960397 1.145749847729765 1.048609409791273 0.9581500441800708 0.9062358579896932 1.0210034813608004 1.1167069658050797 0.9257198580466799 1.0 17.1237739065623 -6.011403226868877 5.766032923113296 0.9920432366409696 1.0996848989629329 0.4159766817598647 0.05906831637401683 0.17284542808422826 21.069183882416436 0.018208938718873934 0.02534328112556812 9.740848148782549e-07 6.011403226868877 0.10764166232196326 RKEDEVEEWQHR ddPTM_PC-9_Lapatinib_30min_R1 5 RKEDEVEEWQHR 12 2 P15311;E7EQR4 P15311 EZR Ezrin 0 ;;;; 97.911 0.00097651 283143000.0 312114.6 306423.9 284279.5 275723.0 306477.0 269296.0 238762.0 252460.0 292375.0 238188.2 False True 307663.7885691925 305714.39428617776 260907.1368606035 296000.58920496405 288450.6254169652 257778.8378396372 251123.92808856146 264190.21325054206 259444.64865475846 279358.71300417377 1.101321613564979 1.0943435090983191 0.9339502392993392 1.0595717098701756 1.0325456554228027 0.9227520955674858 0.8989300007435584 0.9457024282847226 0.9287150769873508 1.0 18.091759292086486 -6.733161093984556 6.751046897065196 0.9332168584018048 1.0423636153460611 0.5312742398941777 0.04921493266388687 0.1434051339474887 21.655544278030497 0.016934803700326483 0.016545162569063368 1.8485827921530691e-07 6.733161093984556 0.10914675694425635 RKELEEVS(ph)PETPVVPATTQR ddPTM_PC-9_AZD4547_30min_R2 2 RKELEEVSPETPVVPATTQR 20 2 Q15149 Q15149 PLEC Plectin 1 RKELEEVS(0.631)PET(0.369)PVVPATTQR;RKELEEVS(0.993)PET(0.007)PVVPATTQR 79.462 0.00051394 43009000.0 99664.0 78356.0 111979.0 154097.0 141160.0 108666.0 100583.0 133626.0 89468.0 113468.0 True False 131355.0788600195 103683.04466490606 110494.08529422122 118572.3174249172 121562.3705989634 101871.09784175525 109534.69214491031 112977.17212000457 94197.09582745792 109495.51985697137 1.1996388439600287 0.9469158628621713 1.0091196921897283 1.082896520148061 1.1102040591044673 0.9303677262304839 1.0003577524266756 1.031797212046494 0.8602826485549634 1.0 16.740512315839894 -6.765826979101219 24.99789878637297 0.9687856852373189 1.06029205686802 0.32213880210353585 0.07555323723268959 158.738421343811 904388.702527544 0.025947636195950266 0.023675787121394044 1.714640276153383e-07 6.765826979101219 0.09150637163070119 RKELEEVS(ph)PETPVVPATTQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RKELEEVSPETPVVPATTQR 20 2 Q15149 Q15149 PLEC Plectin 1 RKELEEVS(0.86)PET(0.139)PVVPATTQR;RKELEEVS(0.84)PET(0.16)PVVPATTQR 56.553000000000004 0.0065813 22515000.0 94611.0 86605.0 86459.0 114130.0 126458.0 115091.0 122367.0 117038.0 111171.0 91193.0 True False 110626.7736475722 95202.57204749476 88520.51045758362 107735.66611445253 101679.46268634846 109055.42535387374 110775.51189963923 113965.87651201115 112796.66556013093 107725.56901660895 1.0269314393736546 0.8837509322676828 0.8217223753437373 1.0000937298167534 0.9438749185968254 1.012344853217343 1.0283121538449247 1.0579278211511705 1.0470742145046374 1.0 16.717001193356417 -6.651217907785596 1.3158647292866457 1.039782298861809 0.9173296989993013 0.4240745637907266 0.05500328527776911 0.3937344186988663 1.4279734761709324 0.025540209643555908 0.025464512305525582 2.2324518063542088e-07 6.651217907785596 -0.12245259986250778 RKELEEVSPET(ph)PVVPATTQR ddPTM_PC-9_Lapatinib_30min_R1 2 RKELEEVSPETPVVPATTQR 20 2 Q15149 Q15149 PLEC Plectin 1 RKELEEVS(0.393)PET(0.607)PVVPATTQR;RKELEEVS(0.046)PET(0.954)PVVPATTQR 75.743 0.0010747 51662000.0 148179.0 89859.0 102461.0 95035.0 100434.0 88716.0 74804.0 78585.0 107077.0 67564.0 True False 146065.9402872991 89650.93700642059 94037.05209089782 102024.19092746626 94526.66958084115 84921.82348709684 78676.98510121687 82236.34598864695 95016.86068920263 79242.34737662901 1.8432813403806159 1.1313513540975868 1.186701999676403 1.287495818902966 1.192880734988423 1.071672234587827 0.9928654022233206 1.0377828107209879 1.1990667090867377 1.0 16.27398399701135 -4.7613991790674195 9.116043605490205 1.1268513041720252 1.8480775987186124 0.8477897219503201 0.0916434342647667 0.032289559584873076 38.56387539183718 0.02503880117309157 0.1432466470813623 1.7322111147674497e-05 4.7613991790674195 0.7212262945465873 RKEQEEEEQKER ddPTM_PC-9_Lapatinib_30min_R1 1 RKEQEEEEQKER 12 3 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-3;Q9UKV3-2;G3V3B0;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 0 53.211000000000006 0.029192000000000003 1595400.0 5879.3 4213.2 4256.0 5388.5 5356.6 4755.1 4728.1 6616.2 4880.9 3765.5 False True 5795.4601038684295 4203.444594258238 3906.088108635094 5784.788265509053 5041.535319480797 4551.735457679496 4972.897883229024 6923.612805625586 4331.161643844419 4416.361657786635 1.3122702697253654 0.951789033592166 0.8844583870861525 1.3098538375609932 1.141558529427022 1.030652788512956 1.1260169045397679 1.5677187110386062 0.9807080985335526 1.0 12.10864260454335 -7.545892327380289 24.999088178627307 1.2339015035823477 1.097336436912293 0.009808392532437926 0.19862385379106798 607.5258238315405 659932.4063224649 0.09054867986278058 0.052281636522728374 2.8451664089452375e-08 7.545892327380289 -0.13656506667005464 RKPEEES(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 RKPEEESPR 9 2 P49321;P49321-3;P49321-4;P49321-2;H0YF33;Q5T624 P49321 NASP Nuclear autoantigenic sperm protein 1 RKPEEES(1)PR 54.65 0.030118000000000002 1664400.0 10662.0 8451.9 5482.8 5783.1 5378.3 6563.1 9186.7 7428.0 14620.0 9601.5 True False 14052.294216623135 11183.81138908725 5410.094489602122 4449.89564300433 4631.61588121567 6152.70831948561 10004.298503003947 6280.173278459239 15392.783352678454 9265.35440746915 1.516649401483774 1.2070570533245397 0.5839058336765662 0.4802725775300189 0.49988545257178185 0.6640553667893891 1.0797534625269278 0.6778125263504821 1.6613269903922674 1.0 13.177630446248596 -8.248004231291993 24.909616480533554 1.330663535169493 0.8214368178076622 0.23702117276132229 0.35199914440510693 969.3448072905112 1797235.7354399809 0.2560349221749572 0.09557693208804603 5.6493147070908876e-09 8.248004231291993 -0.5092267173618309 RKPEEES(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RKPEEESPR 9 2 P49321;P49321-3;P49321-4;P49321-2;H0YF33;Q5T624 P49321 NASP Nuclear autoantigenic sperm protein 1 RKPEEES(1)PR 72.531 0.010241 1857200.0 4844.2 10840.0 8847.2 3203.3 8764.5 6122.4 5835.4 5851.5 5825.0 7147.9 True False 5664.227382688796 11916.123560935757 9058.150801192838 3023.829486238721 7047.159141489684 5801.330566130775 5282.628667362565 5697.904325176738 5910.179605182674 8443.757687254736 0.6708183243153166 1.411234666163184 1.0727629968426837 0.35811419491620194 0.8345998786922652 0.6870555481343904 0.6256253273748398 0.6748067076554468 0.6999466143022648 1.0 13.043669462540437 -5.653951519237181 10.658622814065547 0.6861116643541125 1.0907259664319968 0.33594362124112087 0.22610704592722455 0.3286775729152938 30.43396573797637 0.05737274952234622 0.09940969057014662 2.218444053287664e-06 5.653951519237181 0.4046143020778843 RKPEEESPR ddPTM_PC-9_AZD4547_30min_R2 1 RKPEEESPR 9 2 P49321;P49321-3;P49321-4;P49321-2;H0YF33;Q5T624 P49321 NASP Nuclear autoantigenic sperm protein 0 87.806 0.042962 689270.0 891.11 1286.1 720.41 1071.1 1839.7 1101.1 2169.9 561.08 1166.2 1121.8 False True 1174.464443760555 1701.8066739437415 710.8568926924678 824.1744433300372 1584.2894105335274 1032.2480429348327 2363.0168963467017 474.3779783357439 1227.8429511555141 1082.526123449345 1.084929424167852 1.572069843932385 0.6566648853030946 0.7613436992207635 1.4635114813537906 0.953554857083442 2.182872861134492 0.43821388515243676 1.1342386336536006 1.0 10.080186125056187 RKPNAGGS(ph)PAPVR ddPTM_PC-9_AZD4547_30min_R2 1 RKPNAGGSPAPVR 13 2 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 RKPNAGGS(1)PAPVR 58.81399999999999 0.020427 103840000.0 195680.0 199390.0 360460.0 388780.0 356390.0 296230.0 287910.0 378020.0 256030.0 337850.0 True False 257902.1696031525 263838.91821603465 355680.06487962 299152.77759112336 306911.40023919265 277706.69127107976 313533.4322444255 319605.6950354285 269563.2231043952 326021.974333536 0.7910576277269774 0.8092672856036228 1.090969605980431 0.9175847063764967 0.9413825582358067 0.8518035995542208 0.9616941707237988 0.9803194882454661 0.8268253195369561 1.0 18.31460968181834 -5.040049734630518 24.67220099960169 0.9421586884416757 0.7956098922246713 0.4089032722540672 0.07029880679417741 358.9542732469212 221130.05023273683 0.017375089351844546 0.04598700333886028 9.119064034790467e-06 5.040049734630518 -0.14654879621700445 RKPS(ph)IVTK ddPTM_PC-9_AZD4547_30min_R2 1 RKPSIVTK 8 2 P46100-4;P46100;A0A096LNW1;A0A096LNL9;P46100-6;A0A087WWG0;A0A096LNL7;A0A096LNL6;A0A096LNN3 P46100-4 ATRX Transcriptional regulator ATRX 1 RKPS(0.99)IVT(0.01)K 44.188 0.045252 24375000.0 147330.0 137890.0 151800.0 227220.0 184490.0 199080.0 133620.0 171360.0 145110.0 153460.0 True False 194177.87534562766 182460.24591408306 149787.03281564187 174837.9395140055 158876.74802920624 186631.49612884084 145511.921143761 144880.249461063 152780.21835206347 148087.41210958833 1.311238224636752 1.2321117866457008 1.0114771450310427 1.1806401166941936 1.072857886878552 1.2602792733708448 0.9826083059381076 0.9783427733469207 1.031689433798751 1.0 17.17608948671179 -1.5228787452803376 0.24485973530964988 0.9924748013258281 2.7873955133364996 0.5026145154976194 0.08513253435350322 45.62435200581737 0.6150087573935422 0.11819856374048662 33.49688460901845 0.029999999999999995 1.5228787452803376 1.7949207120106716 RKPS(ph)PEPEGEVGPPK ddPTM_PC-9_AZD4547_30min_R2 5 RKPSPEPEGEVGPPK 15 2 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 RKPS(1)PEPEGEVGPPK;RKPS(1)PEPEGEVGPPK;RKPS(1)PEPEGEVGPPK;RKPS(1)PEPEGEVGPPK;RKPS(1)PEPEGEVGPPK 142.72 1.9176e-06 315840000.0 279087.0 324051.0 340227.0 345219.0 375667.0 366853.0 317763.0 400336.0 362597.0 358814.0 True False 367830.8606297786 428794.14858731336 335715.36767962726 265634.09313038195 323512.1215344345 343913.6239167847 346043.29141150083 338473.27000609325 381763.13716355327 346252.0310744823 1.0623211638306735 1.2383873886795351 0.9695693816952989 0.767169776033 0.9343255562444449 0.993246517138279 0.9993971453038594 0.9775343958438304 1.1025585495596189 1.0 18.401463008306187 -5.287964202314817 18.45598132518634 0.9608234844339172 1.1503533184321717 0.4030320619360026 0.08844326946523681 24.67458687819882 17168.904066422907 0.02426240981268538 0.05061997649303986 5.1527111519501305e-06 5.287964202314817 0.18952983399825452 RKPS(ph)PEPEGEVGPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 RKPSPEPEGEVGPPK 15 2 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 RKPS(1)PEPEGEVGPPK;RKPS(1)PEPEGEVGPPK;RKPS(1)PEPEGEVGPPK;RKPS(1)PEPEGEVGPPK;RKPS(1)PEPEGEVGPPK;RKPS(1)PEPEGEVGPPK 110.26 0.0015325999999999998 287271700.0 513665.0 620314.0 514458.0 592717.0 604649.0 485756.0 586540.0 474769.0 449505.0 419529.0 True False 600618.3391538003 681894.6744075925 526724.62981283 559508.9881044402 486172.36895916384 460282.10023543466 530978.6850181373 462306.81680933665 456078.16024508746 495586.2867102631 1.2119349450541648 1.375935316802363 1.0628313251144728 1.128983999574525 0.9810044829658433 0.9287627857720193 1.0714152091310103 0.9328482833497312 0.9202800248420242 1.0 18.918776741881395 -5.639427807266908 1.1843078826896134 0.9704330127036482 1.305403951839413 0.7225040753306604 0.07271257745746003 0.2769794534315055 0.7249660927535244 0.024461616878013223 0.07903941963706719 2.2938879115400234e-06 5.639427807266908 0.3349709391357647 RKPS(ph)PEPEGEVGPPK ddPTM_PC-9_Lapatinib_30min_R1 3 RKPSPEPEGEVGPPK 15 2 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 RKPS(1)PEPEGEVGPPK;RKPS(1)PEPEGEVGPPK;RKPS(1)PEPEGEVGPPK 118.05 0.00033471 231920000.0 250603.0 321267.0 369982.0 359493.0 395560.0 390935.0 342617.0 336549.0 368475.0 312883.0 True False 247029.35526503873 320523.1260000854 339563.50813182024 385931.3144534936 372293.93850088195 374215.62136399484 360356.0318221439 352186.2951725286 326973.46528623236 366964.40965960873 0.6731697918448818 0.8734447198773263 0.9253309018353981 1.0516859518106354 1.0145232853676922 1.0197599862916196 0.9819917745058855 0.9597287527125911 0.8910222808515097 1.0 18.485280623343385 -4.711687327837768 1.480819503021741 0.9872642731037963 0.5127315463839196 0.830238437897012 0.04289276353713645 0.5571460376047437 1.004640948126115 0.013202792529660237 0.4108673298247324 1.9422837297824788e-05 4.711687327837768 -0.4745327267198767 RKPS(ph)VPDSASPADDSFVDPGER ddPTM_PC-9_AZD4547_30min_R2 2 RKPSVPDSASPADDSFVDPGER 22 2 P16333-2;P16333;C9K098;C9JVV5;H7C5C7;C9J869;C9JAB9 P16333-2 NCK1 Cytoplasmic protein NCK1 1 RKPS(1)VPDSASPADDSFVDPGER;RKPS(0.995)VPDS(0.004)AS(0.001)PADDSFVDPGER 82.665 0.00093175 51085000.0 34694.0 26862.7 40882.0 45765.0 49622.0 39597.0 31088.0 50737.0 33446.0 40863.0 True False 45725.97031997027 35545.542446270534 40339.877968175715 35214.58631220161 42732.84183806851 37120.99333038836 33854.771774563946 42896.76247027276 35213.88727863772 39432.3988077292 1.159604074378743 0.9014298779942143 1.0230135418560597 0.8930368777184092 1.083698763710322 0.9413830873284894 0.8585521753225934 1.0878557675234433 0.8930191503271009 1.0 15.267093856739999 -4.749173940527276 24.928512096001626 0.9666721257802191 1.1596045337354042 0.3624384720356565 0.07752338101782476 595.2768416626977 1209774.9261421023 0.017971527388765146 0.30161611755845996 1.7816650447582138e-05 4.749173940527276 0.19293240795518507 RKPS(ph)VPDSASPADDSFVDPGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RKPSVPDSASPADDSFVDPGER 22 2 P16333-2;P16333;C9K098;C9JVV5;H7C5C7;C9J869;C9JAB9 P16333-2 NCK1 Cytoplasmic protein NCK1 1 RKPS(0.996)VPDS(0.003)AS(0.001)PADDSFVDPGER;RKPS(0.886)VPDS(0.051)AS(0.063)PADDSFVDPGER 62.028 0.015794 21047500.0 41380.0 36637.0 37173.0 38794.0 50452.0 45684.0 33526.0 42616.0 37646.0 40184.0 True False 48384.81670774582 40274.07923450212 38059.345299387554 36620.497951844976 40566.29277271236 43288.25061791428 30350.174572779455 41497.37515538438 38196.50153076513 47469.041103631 1.0192920603160187 0.8484283292468167 0.8017719426077962 0.7714606636333297 0.8545842054013887 0.9119259545060217 0.6393677619592343 0.87419872385436 0.8046613254179132 1.0 15.534699286510627 -4.76515838048134 3.8182602008468605 0.8223798406415804 1.0425640046599614 0.2745526911761088 0.08951439140282977 0.32266837348516564 8.342630540278911 0.021324993573364422 0.2054307843777383 1.7172820067581995e-05 4.76515838048134 0.22018416401838092 RKPS(ph)VPDSASPADDSFVDPGER ddPTM_PC-9_Lapatinib_30min_R1 2 RKPSVPDSASPADDSFVDPGER 22 2 P16333-2;P16333;C9K098;C9JVV5;H7C5C7;C9J869;C9JAB9 P16333-2 NCK1 Cytoplasmic protein NCK1 1 RKPS(0.996)VPDS(0.002)AS(0.002)PADDSFVDPGER;RKPS(0.991)VPDS(0.006)AS(0.003)PADDSFVDPGER 92.03399999999999 0.00054941 54773000.0 75735.0 57822.0 69095.0 49700.0 62878.0 62273.0 64993.0 63522.0 81265.0 76308.0 True False 74655.00501190196 57688.116711573064 63414.27581441308 53355.10379433975 59179.63966290431 59609.728955453174 68358.01952680867 66473.46401846198 72112.07994161261 89497.73612598128 0.8341552339023863 0.6445762676093675 0.7085573173063073 0.5961614908251374 0.6612417500661718 0.6660473385778573 0.7637960744681258 0.7427390557107586 0.8057419445795166 1.0 16.449563568952847 -8.701360672690937 0.7983275501036091 1.0002511665907865 0.6816500770123238 0.700324214936558 0.060900724926283616 0.4747455504821133 0.6331729813612209 0.05939633617050687 0.021242205913091054 1.989020811755357e-09 8.701360672690937 -0.31860108957846267 RKPSVPDS(ph)ASPADDSFVDPGER ddPTM_PC-9_AZD4547_30min_R2 1 RKPSVPDSASPADDSFVDPGER 22 2 P16333-2;P16333;C9K098;C9JVV5;H7C5C7;C9J869;C9JAB9 P16333-2 NCK1 Cytoplasmic protein NCK1 1 RKPS(0.165)VPDS(0.625)AS(0.21)PADDS(0.001)FVDPGER 45.992 0.019868 18784000.0 27611.0 23333.0 46732.0 64591.0 42088.0 33887.0 23872.0 47688.0 34387.0 32008.0 True False 36390.72365552255 30874.9359483161 46112.30314585362 49700.54287100219 36244.8076917623 31768.04053304214 25996.561753808222 40318.91536122293 36204.62661754815 30887.409662476955 1.1781733739793403 0.9995961553818477 1.4929158401350946 1.609087437700548 1.1734492496401758 1.028510997852792 0.8416556143064888 1.305351138273135 1.1721483611987937 1.0 14.914731265607367 -6.515231255782263 23.811598494079316 1.077331342605621 1.3196479411644422 0.27805392246756644 0.1900355470674035 293.62442684904187 914248.9474369711 0.06717669502876802 0.07012977634124802 3.0532948431560196e-07 6.515231255782263 0.24231659855882115 RKPTMT(ph)LEEGLWQAMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RKPTMTLEEGLWQAMR 16 2 E2QRH1;A1L443 E2QRH1 NUTM2F NUT family member 2F 1 RKPT(0.001)MT(0.999)LEEGLWQAMR 56.548 0.04155 0.0 3512.0 3500.9 3631.5 3754.6 5537.7 3609.6 3529.9 4077.1 4767.3 3172.8 True False 4106.512234838165 3848.4462153579316 3718.088732540445 3544.241934577435 4452.627437712071 3420.3062216623653 3195.5223177371086 3970.080445044529 4837.012743654485 3748.0035241290184 1.0956532480295516 1.0267989852683648 0.9920184729293912 0.9456346323476484 1.1879998001727592 0.9125675041773593 0.8525931998635731 1.0592520576583817 1.2905571492968477 1.0 11.871906594180283 -8.00855610423745 24.953685064217634 1.155153939694153 1.0005950774652237 0.21238700253472986 0.10954342652441931 526.8120773222768 1536426.2510184548 0.06379175739612213 0.028191310900136112 9.804916415422565e-09 8.00855610423745 -0.15455886222892934 RKPVLPALTINPTIAEGPS(ph)PTSEGASEANLVDLQK ddPTM_PC-9_AZD4547_30min_R2 3 RKPVLPALTINPTIAEGPSPTSEGASEANLVDLQK 35 2 P36507 P36507 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 1 RKPVLPALT(0.004)INPT(0.01)IAEGPS(0.679)PT(0.265)S(0.034)EGAS(0.008)EANLVDLQK;RKPVLPALTINPTIAEGPS(0.743)PT(0.251)S(0.006)EGASEANLVDLQK;RKPVLPALTINPTIAEGPS(0.469)PT(0.469)S(0.058)EGAS(0.003)EANLVDLQK 97.59200000000001 1.8772e-16 22690400.0 50035.5 46384.5 66857.0 111389.0 108699.0 95645.0 76000.0 94948.0 80665.0 97225.0 True False 65945.74819694684 61377.382526664725 65970.43249641216 85709.98699289482 93608.020131317 89664.30303015374 82763.85276849134 80275.96828798443 84928.78721913863 93821.18234298697 0.7028876267607196 0.6541953639241536 0.7031507261893228 0.9135462254095281 0.9977279948264699 0.9556935948895132 0.8821446362285995 0.8556273357813314 0.9052197499351484 1.0 16.5176260614707 -5.750739432204299 4.801066950461311 0.9271090742783483 0.6793174647007403 0.8620962500371264 0.04467072884347736 0.06822068009702321 4.058730204046758 0.013615731215498209 0.022717937507035147 1.7752542776431977e-06 5.750739432204299 -0.24779160957760804 RKPVLPALTINPTIAEGPS(ph)PTSEGASEANLVDLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RKPVLPALTINPTIAEGPSPTSEGASEANLVDLQK 35 2 P36507 P36507 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 1 RKPVLPALTINPT(0.006)IAEGPS(0.892)PT(0.092)S(0.01)EGASEANLVDLQK;RKPVLPALT(0.012)INPT(0.01)IAEGPS(0.391)PT(0.391)S(0.129)EGAS(0.068)EANLVDLQK 88.47 2.1075e-12 13212500.0 20807.4 23875.8 27131.5 41233.0 43436.0 42124.0 42179.0 41529.0 37672.0 33761.0 True False 24329.6818551172 26246.031634334853 27778.417856786742 38922.84868918966 34925.027607934964 39914.943284936104 38183.49977048456 40438.907753612686 38222.88173157798 39881.60204807103 0.6100477565016464 0.6580987294015764 0.6965221162205121 0.9759600088851561 0.8757177699591483 1.0008360054549685 0.957421412621798 1.013974004977782 0.9584088845153783 1.0 15.283435743658297 -5.704318551726435 3.8055302207799286 0.968005845314443 0.6423016940241021 0.9325309339669468 0.03885961023142961 0.05183751921034931 1.5146543132360126 0.011161545859472396 0.01971381133419143 1.9755200794797235e-06 5.704318551726435 -0.3257041512903409 RKPVLPALTINPTIAEGPSPT(ph)SEGASEANLVDLQK ddPTM_PC-9_Lapatinib_30min_R1 1 RKPVLPALTINPTIAEGPSPTSEGASEANLVDLQK 35 2 P36507 P36507 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 1 RKPVLPALTINPT(0.002)IAEGPS(0.416)PT(0.537)S(0.037)EGAS(0.007)EANLVDLQK 81.28 5.7476e-09 7257000.0 51458.0 37894.0 45802.0 41834.0 54603.0 52698.0 50612.0 43751.0 51313.0 37585.0 True False 50724.199483758515 37806.2587712004 42036.33636083284 44910.611914133005 51391.35889362836 50444.22938503799 53232.44171358206 45783.831180878005 45533.589590155214 44081.51717113549 1.1506908731574383 0.8576442281790583 0.9536045730376577 1.0188082170533914 1.1658255475671182 1.1443396829832524 1.2075909616930922 1.0386174097214873 1.0329406180232503 1.0 15.427886258122909 -6.059104237737504 5.28784561760026 1.107518065496892 0.9756628450347057 0.23585078324025677 0.09041690573509359 0.26185725941458804 15.265543096194735 0.02688922466983692 0.03577169825046785 8.727618662077147e-07 6.059104237737504 -0.13185522046218623 RKQEELQQLEQQR ddPTM_PC-9_AZD4547_30min_R2 1 RKQEELQQLEQQR 13 2 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 116.24 0.0011225 3323700.0 20661.0 17792.0 25755.0 36601.0 28056.0 24628.0 28706.0 25864.0 22132.0 24428.0 False True 27230.768224502972 23542.916058476814 25413.471871981943 28163.204929812986 24160.908681811492 23088.00726673243 31260.778389109404 21867.313095593654 23301.852336626504 23572.783155304536 1.1551783276967569 0.9987329838555359 1.0780853369986225 1.1947339753759825 1.0249493461434829 0.9794349319985571 1.3261386312831225 0.9276508824403662 0.9885066257601803 1.0 14.524834482105017 RKQEELQQLEQQR ddPTM_PC-9_Lapatinib_30min_R1 1 RKQEELQQLEQQR 13 2 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 86.803 0.030032999999999997 3651000.0 26313.0 24219.0 24610.0 23295.0 24760.0 24204.0 23766.0 23673.0 25949.0 19053.0 False True 25937.771794786764 24162.922393510915 22586.660797347206 25008.192009841947 23303.665480032952 23168.851342279777 24996.48719206889 24772.934002535363 23026.350364916074 22346.285663473336 1.1607196017002495 1.0812947958061327 1.0107568272192449 1.1191207517193649 1.0428429060192552 1.0368099509329636 1.1185969591773144 1.1085929167650697 1.0304330084956514 1.0 14.447747430187896 -9.188676029201158 0.008899606234759074 1.6510669975776737e-07 2.095507416335589 0.24946207772444295 0.04453634620537668 6130.696362626139 20.384875933679556 2460.4389918616403 2337.887454999813 6.476255450435594e-10 9.188676029201158 2.0955072512288893 RKS(ph)GGNEVSIEER ddPTM_PC-9_Lapatinib_30min_R1 1 RKSGGNEVSIEER 13 2 Q15061 Q15061 WDR43 WD repeat-containing protein 43 1 RKS(1)GGNEVSIEER 63.76 0.014121000000000002 7962300.0 44416.0 32181.0 36401.0 33699.0 33578.0 33053.0 29040.0 23470.0 37325.0 22548.0 True False 43782.61969510315 32106.486871694746 33408.25029192342 36177.336876568515 31603.00805688797 31639.400240306295 30543.5491061887 24560.50188144743 33121.065450325346 26445.39175667857 1.6555859749760071 1.2140673568802969 1.2632919413449957 1.3680015486037267 1.1950289240433312 1.1964050497499632 1.1549667854126295 0.9287252050348195 1.2524323993786513 1.0 14.690728726879206 -1.5228787452803376 0.25863952996997613 1.0389266601863851 4.256491332664027 0.6098691952747555 0.11738082154496846 35.94469496612602 0.49508455017974407 0.14289959900056834 50.88496496005069 0.029999999999999995 1.5228787452803376 3.2175646724776414 RKS(ph)HEAEVLK ddPTM_PC-9_AZD4547_30min_R2 14 RKSHEAEVLK 10 2 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK 98.04799999999999 0.0015696 133565700.0 1104542.0 1035379.0 1234122.0 1711454.0 1542112.0 1410451.0 1082066.0 1417537.0 1213163.0 1341074.0 True False 1455763.3800991687 1370045.013810122 1217756.735919011 1316904.722000716 1328016.3675907347 1322255.2760017063 1178367.7777603976 1198489.2284097024 1277288.3194586474 1294123.407451154 1.1249030592579834 1.058666434686086 0.9409896528472882 1.0176036647033773 1.0261898980765172 1.0217381653006026 0.9105528661144123 0.9261011905890736 0.9869911262746849 1.0 20.303543768438686 -1.5228787464382347 0.694667979792863 0.971610367495258 20.113340561699182 0.557057757661264 0.0408129477464776 220.70780932621614 1.1973582487133054 0.01762747454310696 6555.6036473960585 0.029999999920015296 1.5228787464382347 19.141730194203923 RKS(ph)HEAEVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 14 RKSHEAEVLK 10 2 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK 90.10799999999999 0.0028519 149235900.0 1191831.0 1171093.0 1512565.0 1565672.0 1836556.0 1525495.0 1799450.0 1778671.0 1422687.0 1146120.0 True False 1393584.4485647485 1287351.3735559897 1548630.2860347058 1477952.4738171075 1476696.0356275605 1445495.3567195346 1628993.069110187 1731982.7709077012 1443491.1059156267 1353902.483319072 1.029309323038094 0.9508449754815921 1.1438270518850526 1.091624021690195 1.09069600936654 1.0676510121880596 1.2031834561058892 1.2792522299403506 1.0661706612554025 1.0 20.368692399892595 -5.280127731495084 0.8520302832161883 1.1392139539434505 0.9572731722603595 0.20152092013253364 0.08174700925693122 1.7777625850724923 1.630504881557971 0.03284599162828489 0.26442060815123736 5.2465313044027656e-06 5.280127731495084 -0.18194078168309102 RKS(ph)HEAEVLK ddPTM_PC-9_Lapatinib_30min_R1 8 RKSHEAEVLK 10 2 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK 92.781 0.002306 134958700.0 1119385.0 919007.0 813026.0 677992.0 794810.0 849204.0 647764.0 797475.0 1126175.0 931323.0 True False 1103422.3646299297 916879.0957551226 746182.1406511167 727853.7933950111 748060.8384565819 812885.5245112113 681302.050386406 834528.599825618 999333.3123515099 1092300.9396401052 1.010181649201445 0.8394015444655928 0.6831287180774295 0.6663491415056612 0.6848486633208019 0.7441955737757063 0.6237310851447986 0.7640097793018297 0.9148882657564804 1.0 20.058938957003782 -8.371535903011345 2.940112762005854 0.9946366999585021 0.7419506110138485 0.39420969329626054 0.10404838167998774 0.26338704718661665 4.226598181544763 0.10558418587621073 0.02871128600631566 4.250735646315147e-09 8.371535903011345 -0.2526860889446536 RKS(ph)LSDSESDDSK ddPTM_PC-9_AZD4547_30min_R2 3 RKSLSDSESDDSK 13 2 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 RKS(0.65)LS(0.35)DSESDDSK;RKS(0.5)LS(0.5)DS(0.001)ESDDSK;RKS(0.589)LS(0.408)DS(0.003)ESDDSK 84.89200000000001 0.0026734000000000003 72615000.0 152541.0 130645.0 158304.0 201646.0 178633.0 178194.0 153880.0 180068.0 153915.0 161997.0 True False 201045.86495009466 172873.44134778032 156204.78552600395 155159.63009964413 153832.89138002673 167051.50101056212 167575.02189494052 152242.62815099585 162050.63267629966 156325.53433804933 1.2860718231439974 1.105855432254251 0.9992275810055172 0.9925418183066371 0.9840547932967091 1.0686130178152355 1.0719619325436913 0.9738820263475043 1.0366229251190018 1.0 17.254193922986268 -4.817093717144324 2.4216468964307247 1.017099147519956 1.3359351128552837 0.8657253965567505 0.032433944809760536 0.17730000426076964 1.382574444669052 0.00905842851802774 0.11647102396647213 1.5237239113454656e-05 4.817093717144324 0.31883596533532765 RKS(ph)LSDSESDDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RKSLSDSESDDSK 13 2 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 RKS(0.937)LS(0.062)DS(0.001)ESDDSK;RKS(0.825)LS(0.175)DS(0.001)ESDDSK;RKS(0.581)LS(0.412)DS(0.007)ES(0.001)DDSK 93.766 0.0012657 63777000.0 82723.0 72770.0 76237.0 106460.0 113590.0 110962.0 136532.0 131798.0 111392.0 100411.0 True False 96726.37004627477 79994.1246798243 78054.77921043262 100495.39134797678 91332.85491263772 105142.95738256286 123598.70055392024 128338.4421515244 113020.89726703984 118614.71944696124 0.8154668366393272 0.674403017203896 0.65805306098907 0.8472421619891235 0.7699959611966822 0.8864241965313394 1.042018234585022 1.0819773696713175 0.952840404580456 1.0 16.855923526103737 -6.929565468717793 1.800949515285789 1.0288062122098396 0.7392902248669426 0.8014486570437317 0.062247080180072425 0.14960183690195145 0.9888660498832179 0.02864395568256329 0.023084598448824118 1.1760736813964635e-07 6.929565468717793 -0.28951598734289696 RKS(ph)LSDSESDDSK ddPTM_PC-9_Lapatinib_30min_R1 1 RKSLSDSESDDSK 13 2 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 RKS(0.757)LS(0.242)DS(0.002)ESDDSK 64.827 0.013158000000000001 15998000.0 46729.0 41698.0 42694.0 37836.0 53266.0 66391.0 46663.0 54250.0 53830.0 53646.0 True False 46062.635890950936 41601.450842917475 39183.8641236059 40618.58565719599 50132.998604985274 63551.61169498 49078.98181618745 56770.65304936184 47767.09854497017 62918.63962119827 0.7320984078529205 0.6611943788578242 0.622770364386649 0.6455731703949771 0.7967908859252367 1.0100601678229622 0.7800388265173486 0.9022867212506438 0.7591883555104184 1.0 15.941199857789256 -6.427264677166255 4.1590656296654185 0.8797403824229549 0.6634456606520417 0.6345985193059192 0.07996299759549379 0.15042546978681454 4.577327799326319 0.02481671818352093 0.027936481748857926 3.738826591419066e-07 6.427264677166255 -0.21629472177091325 RKS(ph)QMEEVQDELIHR ddPTM_PC-9_Lapatinib_30min_R1 4 RKSQMEEVQDELIHR 15 2 A0A2R8YE63;Q12929;A0A2R8Y4W2;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 RKS(1)QMEEVQDELIHR;RKS(1)QMEEVQDELIHR;RKS(1)QMEEVQDELIHR;RKS(1)QMEEVQDELIHR 130.47 7.4312e-06 62657200.0 230854.0 187027.0 206141.0 190472.0 158985.0 165578.0 155342.0 138791.0 189531.0 206204.0 True False 227561.97962656163 186593.9504724043 189192.88270727126 204479.9462759654 149633.81487653617 158496.6149211702 163384.84866575658 145239.73654145582 168184.02293009 241846.08665044134 0.9409372000940184 0.7715400859146537 0.7822863099733601 0.8454961959815207 0.6187150553021491 0.6553615033277652 0.6755736713735179 0.6005461512858048 0.6954175908299035 1.0 17.883729667934134 -4.276738253857391 0.6794595038471227 0.6944996894223004 1.2434614305292233 0.2087456788499511 0.11457018331517459 7.654572758167602 1.64193455880098 0.04682724886087687 3.787327237443162 5.287638379008489e-05 4.276738253857391 0.5489617411069229 RKS(ph)S(ph)PKS(ph)SS(ph)AS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 RKSSPKSSSASK 12 3 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 5 RKS(0.999)S(0.999)PKS(0.872)S(0.43)S(0.872)AS(0.828)K 44.733999999999995 0.038422000000000005 11601000.0 9201.5 6225.4 6942.8 8088.8 6125.0 2816.5 6951.6 2522.0 7909.7 6617.0 True False 9070.284922651561 6210.985468787437 6371.989783983025 8683.67733544579 5764.739542213317 2696.0448605821744 7311.519833559972 2639.1813270136518 7018.826293166464 7760.739633401724 1.168739753053129 0.8003084450940416 0.821054446480641 1.1189239358155763 0.7428080072938215 0.34739534991981574 0.9421163676322372 0.3400682733453375 0.9044017226087431 1.0 12.921978438954781 -6.504800516079333 23.676228959227366 0.6652407699107762 0.9506359883726467 0.21706286180782342 0.23832005691105865 521.7041779254619 683253.0271109724 0.07010969440453747 0.07786479812505899 3.1275155949271386e-07 6.504800516079333 0.28539521846187055 RKS(ph)VPSETVVEDSR ddPTM_PC-9_AZD4547_30min_R2 1 RKSVPSETVVEDSR 14 2 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 RKS(0.941)VPS(0.055)ET(0.003)VVEDSR 77.192 0.0049286 8350900.0 52271.0 42050.0 54569.0 85961.0 69881.0 49831.0 43537.0 66534.0 50524.0 55795.0 True False 68892.0906956582 55641.84016743203 53845.379405248794 66144.0195342109 60179.22938386333 46715.059692567156 47411.70865765536 56252.69909922012 53194.59549320972 53841.634032676295 1.279531944625749 1.03343520617638 1.0000695627582592 1.2284920530842047 1.1177080797239691 0.8676382233164758 0.8805770758904042 1.0447806815276177 0.9879825612448188 1.0 15.716434574324314 -6.73730395615494 22.16998627998306 0.954268492961417 1.1244285486602956 0.48063423863744437 0.09112194287924111 61.456515218544915 56451.008957363156 0.0311376507107718 0.031109705209076754 1.8310324618190108e-07 6.73730395615494 0.1701600556988786 RKS(ph)VPSETVVEDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RKSVPSETVVEDSR 14 2 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 RKS(0.949)VPS(0.048)ET(0.003)VVEDSR;RKS(0.921)VPS(0.077)ET(0.002)VVEDSR;RKS(0.992)VPS(0.007)ET(0.001)VVEDSR 80.74600000000001 0.0035914000000000002 16778400.0 99973.0 90698.0 106161.0 142029.0 130811.0 120935.0 98474.0 131073.0 101892.0 90315.0 True False 116896.45434324512 99701.89803779966 108692.28085783448 134071.5755942308 105179.52358462078 114592.95570609985 89145.82982997928 127632.47263332331 103381.97773927437 106688.39456685356 1.0956810702591924 0.934514934286728 1.0187826079782767 1.2566650397032477 0.9858572154135539 1.0740901685824233 0.8355719494318412 1.1963107435583884 0.969008655149391 1.0 16.703043724531092 RKS(ph)VPSETVVEDSR ddPTM_PC-9_Lapatinib_30min_R1 1 RKSVPSETVVEDSR 14 2 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 RKS(0.997)VPS(0.002)ET(0.002)VVEDSR 97.214 0.0077521000000000005 47773000.0 221160.0 106140.0 132300.0 122880.0 99821.0 108090.0 85305.0 96599.0 112140.0 91293.0 True False 218006.2178442229 105894.23935122232 121422.80469276842 131917.00511566334 93949.72503563677 103467.24267009679 89721.67549942943 101087.34219198737 99509.61231344893 107072.87340972411 2.0360546131044996 0.9889922253791431 1.1340202315121684 1.2320301203729809 0.8774372261042215 0.9663254508372999 0.837949637870474 0.9440985281600451 0.9293634245965019 1.0 16.708233498369367 -4.761361604926242 24.98289879606265 0.9913284226041263 2.036055738121317 0.8901123035958665 0.11025908025726876 0.6063433487424026 193546.12462745167 0.030322331488728125 0.1694670419935172 1.7323609880983972e-05 4.761361604926242 1.0447273155171908 RKS(ph)YTSDLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RKSYTSDLQK 10 2 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;E9PJ10;E9PK58;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 RKS(0.993)Y(0.007)TSDLQK 92.23899999999999 0.0024167 13223000.0 106480.0 88984.0 73044.0 99414.0 110070.0 80358.0 49063.0 92490.0 52105.0 64826.0 True False 124504.96092413651 97817.74344523129 74785.64598091271 93844.15588453648 88502.5736441064 76143.88501782577 44415.39745464053 90062.23550125548 52866.937052024616 76578.44063766622 1.6258487361114655 1.2773535557881053 0.9765887808392941 1.2254644401622596 1.15571135827719 0.9943253529815713 0.5799987187620294 1.176078211456255 0.6903631963748977 1.0 16.224650662521398 -1.5228787457110018 0.42379588066091806 0.8922640776502349 14.242523093116626 0.5717562798116009 0.1848974774774716 59.290318028036936 0.7542781681803223 0.12425728832857695 672.8805008225444 0.029999999970250768 1.5228787457110018 13.35025901546639 RKSLS(ph)DSESDDSK ddPTM_PC-9_Lapatinib_30min_R1 1 RKSLSDSESDDSK 13 2 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 RKS(0.048)LS(0.952)DSESDDSK 94.402 0.0012075 15125000.0 125260.0 111330.0 124550.0 114410.0 154710.0 166650.0 140860.0 150780.0 150130.0 138970.0 True False 123473.76943012913 111072.22222509467 114309.97977690323 122824.0930605716 145610.26197156287 159522.7679801241 148153.04156672664 157785.7892494519 133220.77846101372 162990.7793341146 0.7575506414201529 0.6814632255816622 0.7013278925587523 0.7535646713412827 0.8933650269447241 0.978722653096336 0.9089657842731576 0.9680657390195491 0.8173516256887429 1.0 17.314430825486937 -6.248368339254953 2.850194098082813 0.9317779487541072 0.711782280929457 0.8026217071299941 0.05019105523435243 0.11032542697245704 1.8009925948241596 0.01543776177424065 0.019537791114260582 5.644580365464146e-07 6.248368339254953 -0.2199956678246503 RKSY(ph)TSDLQK ddPTM_PC-9_Lapatinib_30min_R1 1 RKSYTSDLQK 10 2 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;E9PJ10;E9PK58;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 RKS(0.382)Y(0.605)T(0.012)S(0.002)DLQK 87.806 0.020669999999999997 13203000.0 149880.0 106230.0 139280.0 132130.0 81860.0 65014.0 72925.0 79270.0 122410.0 131260.0 True False 147742.68371537398 105984.03096175184 127828.93603634801 141847.28097275904 77045.15574295213 62233.50277503619 76700.69967523457 82953.17358936233 108622.89676555447 153948.1161070442 0.9596914041653136 0.6884399344520614 0.830337773977469 0.9213966663556239 0.5004618289020218 0.4042498495516736 0.4982243473632542 0.5388385105776987 0.705581201721404 1.0 17.23208468738853 -6.263473360534534 24.999032842117163 0.5691689919516961 0.8370267925365906 0.3138148515365544 0.1692286709251839 196.47846853089834 2414853.9412133372 0.049988188763700855 0.059530232440038126 5.45163334783882e-07 6.263473360534534 0.2678578005848945 RKT(ph)SDANETEDHLESLICK ddPTM_PC-9_Lapatinib_30min_R1 1 RKTSDANETEDHLESLICK 19 2 F2Z2T1;Q09161 F2Z2T1 NCBP1 Nuclear cap-binding protein subunit 1 1 RKT(0.35)S(0.294)DANET(0.35)EDHLES(0.006)LICK 49.606 0.030497000000000003 16794000.0 46982.0 29208.0 44053.0 33314.0 50249.0 66257.0 59106.0 62801.0 86610.0 51463.0 True False 46312.028064556405 29140.370670534183 40431.13238949761 35764.022692246166 47293.452613335015 63423.34256261073 62166.219472120865 65718.96372632218 76855.06975626737 60358.31097986292 0.7672850235986107 0.48278969701879426 0.6698519513408264 0.5925285534278446 0.783544997293137 1.0507806055701323 1.0299529337867175 1.0888138296024836 1.2733137907372556 1.0 15.881264814720385 -6.665411279134361 1.9844008033081524 1.106675036153772 0.6169554165989108 0.8416815944343132 0.09504245364240718 0.11680951486610117 0.944021914542507 0.03576265812388937 0.035087887453834954 2.1606713875079317e-07 6.665411279134361 -0.4897196195548612 RKT(ph)SQSEEEEAPR ddPTM_PC-9_AZD4547_30min_R2 1 RKTSQSEEEEAPR 13 2 Q7RTP6;A0A5F9ZHV5;J3KSK6;Q7RTP6-2;Q7RTP6-4;Q7RTP6-3;Q7RTP6-5 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 RKT(0.5)S(0.5)QSEEEEAPR 68.676 0.015236000000000001 5003100.0 51649.0 33357.0 50556.0 46985.0 50643.0 49511.0 29231.0 35848.0 33897.0 60134.0 True False 68072.30763406193 44138.997918312256 49885.59440729645 36153.33416101376 43612.09361181135 46415.069343153715 31832.50237204963 30308.51530508973 35688.72621790297 58028.72696336509 1.1730794590244518 0.7606404659915813 0.8596706668886672 0.6230247681262802 0.7515604062681697 0.7998636498170406 0.5485645479030798 0.5223019165011877 0.6150182519157126 1.0 15.824479658883838 -1.5228788834501377 0.8377302649356456 0.6752609004355653 155.49233050817708 0.47691027768760075 0.1410852285893325 512.9300980822105 1.5114300973159525 0.04816989211663427 151194.50553992743 0.029999990455569857 1.5228788834501377 154.8170696077415 RKTS(ph)DANETEDHLESLICK ddPTM_PC-9_AZD4547_30min_R2 1 RKTSDANETEDHLESLICK 19 2 F2Z2T1;Q09161 F2Z2T1 NCBP1 Nuclear cap-binding protein subunit 1 1 RKT(0.147)S(0.621)DANET(0.231)EDHLES(0.001)LICK 58.073 0.0079987 18180000.0 102910.0 78307.0 148550.0 254420.0 179680.0 153200.0 126080.0 159400.0 108900.0 147420.0 True False 135633.23933902537 103618.2063731533 146580.12993915437 195767.39974981642 154734.53350256238 143620.37978168754 137300.8757506761 134768.39264760385 114656.23167624373 142258.87067115548 0.9534255312103112 0.7283778219544309 1.0303760267996775 1.3761349209804346 1.087696906158109 1.0095706447275214 0.9651480790119566 0.9473461444744169 0.8059689433447155 1.0 17.118159090232446 -7.531468377646654 2.030035874601686 0.9043264861889142 1.0356341614214002 0.09949957755353966 0.15501412151411223 0.8845185006652458 7.205063165895632 0.1045562755702395 0.05331241736471224 2.9412478474990225e-08 7.531468377646654 0.131307675232486 RKTS(ph)DANETEDHLESLICK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RKTSDANETEDHLESLICK 19 2 F2Z2T1;Q09161 F2Z2T1 NCBP1 Nuclear cap-binding protein subunit 1 1 RKT(0.202)S(0.771)DANET(0.026)EDHLES(0.001)LICK 47.728 0.024708 5383900.0 23863.0 24590.0 28026.0 49160.0 57884.0 61586.0 59463.0 77095.0 69571.0 57493.0 True False 27902.53458426628 27031.132690351504 28694.246129196887 46405.72457887038 46542.04572377078 58356.32174404319 53830.23416516095 75071.33793890467 70588.34425959889 67916.02578566245 0.41083874183575536 0.3980081634290498 0.4224959543385774 0.6832809199602335 0.6852881214023588 0.8592422932432925 0.7925998840839844 1.1053552835353444 1.0393473917683296 1.0 16.051464419313962 -6.439089947452267 0.5993740622764794 1.0604997655295798 0.32977981726822186 0.9163285685782042 0.0731778071850709 0.23805531226359988 0.18494235507458323 0.05529523097841284 0.08866447178078928 3.6383967288355053e-07 6.439089947452267 -0.730719948261358 down RKTS(ph)DANETEDHLESLICK ddPTM_PC-9_Lapatinib_30min_R1 2 RKTSDANETEDHLESLICK 19 2 F2Z2T1;Q09161 F2Z2T1 NCBP1 Nuclear cap-binding protein subunit 1 1 RKT(0.092)S(0.498)DANET(0.405)EDHLES(0.005)LICK;RKT(0.15)S(0.665)DANET(0.15)EDHLES(0.034)LICK 48.31399999999999 0.023443000000000002 27768000.0 156492.0 86515.0 143720.0 124185.0 162606.0 239873.0 196430.0 191046.0 280107.0 158822.0 True False 154260.39538288198 86314.6798329658 131903.89637524323 133317.97916901566 153041.83477569625 229614.19096127411 206600.18426062854 199922.69460771253 248558.40000252603 186274.171082987 0.8281362600408911 0.46337438696485594 0.7081169418624267 0.7157083475068649 0.8215945017278566 1.2326678982185817 1.109118795480164 1.0732711542634914 1.3343685737932542 1.0 17.507068117402127 -6.5936926038165025 3.246104853147113 1.1521929203055257 0.6702291114809464 0.7739641347084131 0.12099110081591936 0.11058558505469544 2.357842689979736 0.040820429980556794 0.041535423447484045 2.548633552104821e-07 6.5936926038165025 -0.48196380882457923 RKTSDANET(ph)EDHLESLICK ddPTM_PC-9_AZD4547_30min_R2 1 RKTSDANETEDHLESLICK 19 2 F2Z2T1;Q09161 F2Z2T1 NCBP1 Nuclear cap-binding protein subunit 1 1 RKT(0.165)S(0.162)DANET(0.671)EDHLES(0.002)LICK 55.705 0.014315999999999999 28111000.0 68183.0 56861.0 98167.0 177800.0 123120.0 96093.0 74621.0 100060.0 71687.0 115420.0 True False 89863.7757054975 75240.20627254098 96865.24143882157 136810.95698261677 106026.91320589655 90084.28951933252 81262.12443996836 84598.02615005792 75476.22846808888 111379.18093111401 0.8068274066504099 0.675532048660653 0.8696889367388233 1.2283350967290005 0.9519455280558425 0.8088072543382054 0.7295988690222772 0.7595497241300442 0.6776511358506897 1.0 16.76512006282035 -6.908167198189215 5.332966963857192 0.7713550728093109 0.9088044548446897 0.11194342247079803 0.15276626230816595 0.45000731434293745 20.59666386473558 0.05961584661791584 0.05239344593769011 1.2354717000239607e-07 6.908167198189215 0.13744938203537882 RLAAAEETAVS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 RLAAAEETAVSPR 13 1 Q9BUH6 Q9BUH6 C9orf142 Protein PAXX 1 RLAAAEETAVS(1)PR;RLAAAEETAVS(1)PR;RLAAAEETAVS(1)PR;RLAAAEETAVS(1)PR 145.94 4.6201999999999996e-05 86115900.0 105963.4 81760.6 136316.0 156045.0 143188.0 140730.0 115438.0 158836.0 138008.3 120721.0 True False 139657.55702435982 108188.11503432441 134508.36077270782 120071.23612121718 123308.81780479112 131930.13085298266 125711.75836696186 134291.54588817348 145303.13698847158 116494.59453461239 1.1988329379769234 0.9286964383757738 1.1546317776379165 1.0307022106982149 1.0584939009179015 1.13250002182534 1.0791209572355815 1.1527706193120688 1.2472951004203008 1.0 16.82990348838046 -7.194180575772897 1.4704682943072853 1.1413931943693862 1.0699278141568187 0.04525414552947238 0.08985514363058461 0.9872736655196173 4.199034578570589 0.048363128265320375 0.030346962013371632 6.394688947344067e-08 7.194180575772897 -0.07146538021256754 RLAAAEETAVS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RLAAAEETAVSPR 13 1 Q9BUH6 Q9BUH6 C9orf142 Protein PAXX 1 RLAAAEETAVS(1)PR;RLAAAEET(0.002)AVS(0.998)PR;RLAAAEETAVS(1)PR 104.94 0.00076994 29715300.0 58602.0 61342.0 68014.0 62603.0 77733.0 62250.0 66713.0 62399.0 52866.0 54413.0 True False 68522.16115774092 67431.6283648451 69635.71170453147 59095.55687166445 62501.77666100952 58985.50041513803 60393.46167970637 60761.09236720549 53639.06523735402 64277.64616692904 1.0660340762912954 1.0490681035476186 1.0833581479273142 0.9193796038858252 0.9723718958017289 0.9176673996734835 0.9395717684319765 0.945291185825457 0.8344901911630892 1.0 15.972029478359039 -5.763162018160233 24.999851612777974 0.9317174215896501 1.0644449264385942 0.687971941114907 0.04118335188074003 24.210358838972386 351364.04152860504 0.011011160742210025 0.017334922315248264 1.7251941699509033e-06 5.763162018160233 0.13272750484894413 RLAAAEETAVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 RLAAAEETAVSPR 13 1 Q9BUH6 Q9BUH6 C9orf142 Protein PAXX 1 RLAAAEET(0.001)AVS(0.999)PR;RLAAAEETAVS(1)PR;RLAAAEETAVS(1)PR;RLAAAEETAVS(1)PR 135.86 7.7525e-05 62909700.0 168709.0 157372.0 186313.0 159273.1 192087.0 163165.0 163846.0 134505.0 184883.0 152119.0 True False 166303.17872255837 157007.61480290702 170995.06432897827 170986.575093486 180788.8203175721 156186.81330619217 172329.1441753648 140754.5933346439 164059.5296356998 178412.5664641739 0.9321270469810368 0.8800255380802164 0.958425001768667 0.9583774197195966 1.0133188704164253 0.8754249568936907 0.9659025010997156 0.7889275745770301 0.9195514244712338 1.0 17.444857709297345 RLADY(ph)CRKAY(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLADYCRKAYK 11 3 F5H1D6;Q07864 F5H1D6 POLE DNA polymerase;DNA polymerase epsilon catalytic subunit A 2 RLADY(1)CRKAY(1)K 73.233 0.013246 0.0 9975.6 8381.9 8487.6 9493.9 13488.0 9472.6 13113.0 11476.0 12443.0 7489.0 True False 11664.27205291902 9213.999637952717 8689.976573402246 8961.987562639088 10845.123224418154 8975.840180440739 11870.841710101327 11174.767159827084 12624.95533515674 8846.69641710862 1.3184890158954128 1.0415186871489983 0.982284930292929 1.0130321127904316 1.2258952622636374 1.0145979648496095 1.3418389362999181 1.2631570738898885 1.4270813352135998 1.0 13.110923101165213 -7.264554982432823 24.999463010702055 1.279949095797803 1.0931902224085592 0.22567266011029574 0.14144748229605328 361.50202947617043 2900656.518376072 0.055603468677955556 0.0392612646328159 5.438072804195599e-08 7.264554982432823 -0.1867588733892438 RLAEDEAFQR ddPTM_PC-9_AZD4547_30min_R2 1 RLAEDEAFQR 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 146.71 9.0944e-05 2410600.0 9397.9 11889.0 13645.0 19514.0 20272.0 16667.0 12497.0 16749.0 14874.0 16759.0 False True 12386.236711536534 15731.886747933402 13464.058384515381 15015.348788294612 17457.582720191145 15624.809855231011 13609.208790103117 14160.826903730973 15660.209274127177 16172.272511042596 0.7658933958155283 0.9727690859272564 0.8325396678371566 0.928462513727862 1.0794761656576666 0.9661480688358565 0.8415149312386746 0.8756238119325415 0.9683369646061939 1.0 13.98123479862399 -4.753454303155752 24.753421420210515 0.93494933855537 0.765893044930763 0.3457319910317763 0.07170589666541706 333.36648056191916 1033329.533784209 0.018882969638778935 0.20166506206825616 1.764191384467183e-05 4.753454303155752 -0.16905629362460695 RLAS(ph)TSDIEEK ddPTM_PC-9_AZD4547_30min_R2 1 RLASTSDIEEK 11 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 RLAS(0.989)T(0.011)S(0.001)DIEEK 154.13 0.00073079 43297000.0 47796.0 61461.0 56165.0 53999.0 54534.0 72829.0 62300.0 59548.0 65288.0 46558.0 True False 62994.13378144055 81327.06631463839 55420.21540244095 41550.36482623352 46962.89542536033 68274.9911169747 67844.57930890794 50346.2248769104 68738.99039190632 44928.018591152286 1.4021124402278011 1.8101636543271507 1.2335334862364684 0.9248207717403337 1.0452919335866009 1.5196528415437436 1.5100728106061778 1.1205974902891693 1.529980456459372 1.0 15.455327817289907 -5.283129012232739 24.036874349147652 1.2418672861952196 1.6061380232243467 0.29370491875683913 0.22973835306809706 554.9155363347032 614967.7760381927 0.06239063616705996 0.1300944592265178 5.210399071416961e-06 5.283129012232739 0.36427073702912716 RLAS(ph)TSDIEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RLASTSDIEEK 11 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 RLAS(0.535)T(0.296)S(0.168)DIEEK;RLAS(0.876)T(0.102)S(0.023)DIEEK;RLAS(0.73)T(0.06)S(0.209)DIEEK 82.705 0.007735 26855700.0 44915.0 48426.0 50661.0 56998.0 152990.0 154828.0 246600.0 206356.0 196544.0 193866.0 True False 52518.22238831327 53233.41324371541 51868.9503729124 53804.58685000924 123012.7077479044 146708.54712088333 223240.26277060827 200939.37365225484 199418.084175283 229012.3711575886 0.22932482696392978 0.23244776242714107 0.22648973114740686 0.2349418355787648 0.5371443783849413 0.6406140697959494 0.9747956481223958 0.8774171134797949 0.870774286853084 1.0 17.805066008678807 -6.7151498349859615 1.3063848311873218 0.9305156013781142 0.21620903060003258 0.966467360196804 0.05786461748260427 0.06857434979686582 0.24569439940260132 0.026663662138259922 0.025091005888470644 1.9268600167552165e-07 6.7151498349859615 -0.7143065707780816 down RLAS(ph)TSDIEEK ddPTM_PC-9_Lapatinib_30min_R1 2 RLASTSDIEEK 11 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 RLAS(0.919)T(0.04)S(0.04)DIEEK;RLAS(0.451)T(0.451)S(0.098)DIEEK 111.83 0.0025901 61376000.0 28400.3 21667.3 23908.0 18646.4 75999.0 116248.0 180642.0 147872.0 131032.0 150482.0 True False 27995.306514022854 21617.130698084937 21942.37652754883 20017.71845856696 71528.8882397828 111276.34402732365 189994.75887190585 154742.67295327614 116273.79633186947 176492.61319533872 0.1586202731501186 0.12248178723581762 0.12432461693602677 0.11341958224853141 0.4052797844894277 0.630487259566864 1.0765026106878661 0.8767657192655981 0.6588026219725117 1.0 17.429248277596365 -6.7217433393895 1.8838979417215225 0.8915161302698298 0.12891689259237257 0.9075959358188135 0.11054119551618487 0.09469625403521705 0.693115358448665 0.04514588009291124 0.04254641742525088 1.8978271732565053e-07 6.7217433393895 -0.7625992376774572 down RLAS(ph)TSDIEEKENR ddPTM_PC-9_AZD4547_30min_R2 1 RLASTSDIEEKENR 14 2 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 RLAS(0.774)T(0.215)S(0.011)DIEEKENR 89.311 0.015108000000000002 42802000.0 75107.0 56926.0 83601.0 174480.0 123500.0 81066.0 66287.0 84476.0 61505.0 100980.0 True False 98989.46367735058 75326.21625139673 82492.39611607703 134256.33168912787 106354.15676517384 75996.9302048453 72186.41458506545 71422.17526536372 64756.028735053864 97444.72093591998 1.0158525031073404 0.7730148491156493 0.8465558249207193 1.377769163887445 1.091430666984133 0.7798978690166415 0.740793486725007 0.7329506881376491 0.6645411687066934 1.0 16.572296409200234 -6.776829882544867 20.91191639969574 0.7642675610939309 1.0172891500579782 0.3225584371364424 0.17075008222951152 43.915755195716535 59668.476864273835 0.06455775835137675 0.05728999933898491 1.671745325295303e-07 6.776829882544867 0.25302158896404725 RLAVPTEVSTEVPEMDT(ph)ST ddPTM_PC-9_AZD4547_30min_R2 2 RLAVPTEVSTEVPEMDTST 19 1 O00488 O00488 ZNF593 Zinc finger protein 593 1 RLAVPTEVSTEVPEMDT(0.365)S(0.365)T(0.269);RLAVPTEVSTEVPEMDT(0.333)S(0.333)T(0.333) 105.0 0.00045857 7551700.0 27319.0 18626.1 33286.0 44871.0 30702.0 24071.0 25955.3 35581.0 20802.3 34072.0 True False 36005.873729499865 24646.622571762317 32844.60589131395 34526.68420003932 26439.557255096108 22565.836564784644 28265.271417921373 30082.774020040142 21901.867109262854 32879.14965070965 1.0950974739920845 0.7496125305427525 0.9989493718735832 1.050108794382829 0.8041435844897359 0.6863266478759918 0.8596716070274434 0.9149498797755813 0.6661324073747793 1.0 15.004885366812102 -6.2842211553965965 24.190855883797035 0.8127310052820476 0.9592761724194306 0.2547374680748713 0.12549723243719044 759.6639011524593 806647.4048812854 0.038050151350537055 0.04317796451954161 5.197312668398448e-07 6.2842211553965965 0.14654516713738308 RLAVPTEVSTEVPEMDT(ph)ST ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLAVPTEVSTEVPEMDTST 19 1 O00488 O00488 ZNF593 Zinc finger protein 593 1 RLAVPTEVSTEVPEMDT(0.366)S(0.366)T(0.268) 99.915 0.00088935 0.0 5486.9 2390.0 6307.9 6252.7 5699.9 5682.5 7104.8 7550.1 5912.3 5546.4 True False 6415.723798785172 2627.263405040264 6458.304258843965 5902.381490526908 4583.045512074514 5384.49969653047 6431.781909702431 7351.917874992203 5998.756202527301 6551.918414721756 0.9792130171171602 0.4009914713127327 0.9857119472569369 0.9008630933597436 0.6994967308775845 0.8218203212713748 0.9816639192653277 1.1221015601282363 0.9155724816488048 1.0 12.677701677140222 -7.264148637256127 3.739632316742907 1.0196780505219232 0.7862636720221072 0.2774886580671829 0.16382819086778927 0.29193687398595786 9.19008856302274 0.06871736999550077 0.047892585773268465 5.443163287340062e-08 7.264148637256127 -0.23341437849981594 RLAVPTEVSTEVPEMDT(ph)ST ddPTM_PC-9_Lapatinib_30min_R1 1 RLAVPTEVSTEVPEMDTST 19 1 O00488 O00488 ZNF593 Zinc finger protein 593 1 RLAVPTEVSTEVPEMDT(0.333)S(0.333)T(0.333) 67.29899999999999 0.017075999999999997 4722200.0 11286.0 9620.3 10496.0 8940.5 11808.0 9888.5 8376.2 6324.8 9615.2 6541.4 True False 11125.059570401081 9598.02478641947 9633.059395731665 9598.0141946337 11113.476655421204 9465.591906219357 8809.878650938628 6618.673297817583 8532.234923455278 7672.072274132388 1.4500723106990256 1.2510341982544582 1.2556007101511617 1.251032817690591 1.44856256019538 1.2337725151696115 1.1483049606613502 0.8626969430584607 1.1121160774544663 1.0 12.90540059587335 -7.383810143062559 2.5454203940456006 0.9920097460925672 1.3165959880520017 0.7066706386350843 0.09348070227609574 0.1562289408880328 1.9697370947514181 0.04514959335549057 0.02743438316812369 4.1322811003518616e-08 7.383810143062559 0.32458624195943453 RLAVPTEVSTEVPEMDTS(ph)T ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLAVPTEVSTEVPEMDTST 19 1 O00488 O00488 ZNF593 Zinc finger protein 593 1 RLAVPTEVSTEVPEMDT(0.268)S(0.366)T(0.366) 75.89 0.036824 0.0 2365.6 0.0 2332.8 2462.6 1643.3 2504.3 2606.4 1845.6 2703.0 1805.5 True False 2766.0493572702617 0.0 2388.422799193266 2324.628505856921 1321.3071615277547 2372.970099431809 2359.5029232981105 1797.154955574842 2742.526261426396 2132.8228576698643 1.296895964577295 0.0 1.1198411488343893 1.0899304166294461 0.6195109719385226 1.1125959621533261 1.10628171243246 0.8426180116703439 1.2858668742994626 1.0 11.058548431787438 -6.048944396604575 0.74108151806736 1.057216660513621 0.7057065968726864 0.07000372572636393 0.3553930334810441 2.0229685494889313 2.233888946480454 0.18945014517308753 0.4467858578209117 8.934198623403675e-07 6.048944396604575 -0.3515100636409346 RLAVPTEVSTEVPEMDTS(ph)T ddPTM_PC-9_Lapatinib_30min_R1 1 RLAVPTEVSTEVPEMDTST 19 1 O00488 O00488 ZNF593 Zinc finger protein 593 1 RLAVPTEVSTEVPEMDT(0.095)S(0.453)T(0.453) 118.5 5.351e-05 4298900.0 19216.0 14256.0 15125.0 12764.0 13943.0 19369.0 14570.0 14496.0 24190.0 15298.0 True False 18941.97631621719 14222.991107886035 13881.480884188399 13702.70713945579 13122.900152992699 18540.633021344274 15324.363308442471 15169.537080249758 21465.46746800724 17942.23891669633 1.055719768539619 0.7927099384821304 0.7736760695606861 0.7637122213719157 0.7313970243023045 1.0333511390315455 0.8540942621259062 0.8454651145088473 1.1963650449461094 1.0 14.131072307291266 -8.247446501255393 24.644110888807205 1.0981825125643008 0.8499772291820732 0.4257395675330675 0.11219502828989322 525.8803165126532 926179.6905724714 0.07710069476088914 0.028797283145826465 5.656574335414081e-09 8.247446501255393 -0.24820528338222758 RLAVPTEVSTEVPEMDTST(ph) ddPTM_PC-9_Lapatinib_30min_R1 2 RLAVPTEVSTEVPEMDTST 19 1 O00488 O00488 ZNF593 Zinc finger protein 593 1 RLAVPTEVSTEVPEMDT(0.148)S(0.363)T(0.489);RLAVPTEVSTEVPEMDT(0.236)S(0.322)T(0.443) 95.751 0.0012802 10483500.0 18579.1 15374.1 14824.6 13733.4 17140.9 12506.2 10158.0 12648.6 18411.6 13208.9 True False 18314.158627010336 15338.502216031882 13605.778612610862 14743.400049279397 16132.705962306005 11971.338979376102 10683.931536524276 13236.30013198449 16337.891725256794 15492.040765247095 1.1821656620020022 0.9900891979603074 0.8782431455468644 0.9516757845327192 1.0413544740016498 0.772741252155178 0.689640035061828 0.8543935774863921 1.0545990662448537 1.0 13.919239582293674 -6.752334655763608 24.997132153888696 0.8536347082507775 0.9972551715161335 0.22304032597406853 0.12152259954775026 299.348361460936 821863.5624299881 0.04238521352691725 0.04180973913916005 1.7687454848832252e-07 6.752334655763608 0.14362046326535605 RLDAAYR ddPTM_PC-9_AZD4547_30min_R2 1 RLDAAYR 7 1 Q9Y5A9;A0A024R7W5;A0A087X0Q1;A0A087WY31;Q9Y5A9-2;Q7Z739 Q9Y5A9 YTHDF2;YTHDF3 YTH domain-containing family protein 2;YTH domain-containing family protein 3 0 68.383 0.031173000000000003 1886300.0 2952.2 2282.2 6122.9 8268.5 5730.6 4956.2 3580.1 4335.4 4535.2 4716.5 False True 3890.938190425325 3019.8765191465723 6041.706345368211 6362.325072051552 4935.005107356322 4646.288030509145 3898.721964427313 3665.4635475810687 4774.921413205698 4551.376770590873 0.8548925713131396 0.6635083561219923 1.3274458806414875 1.3978902193205103 1.0842884155942214 1.0208533076258484 0.856602773389198 0.8053526948737332 1.0491158288760618 1.0 12.15208730462316 -7.063568861714713 4.5147904336297735 0.912524953446296 1.074815067584967 0.08750734676948746 0.20662078304346196 0.5717247618775753 23.08935205877998 0.08992211799855823 0.0704459883088345 8.638356800759003e-08 7.063568861714713 0.162290114138671 RLDAAYR ddPTM_PC-9_Lapatinib_30min_R1 2 RLDAAYR 7 1 Q9Y5A9;A0A024R7W5;A0A087X0Q1;A0A087WY31;Q9Y5A9-2;Q7Z739 Q9Y5A9 YTHDF2;YTHDF3 YTH domain-containing family protein 2;YTH domain-containing family protein 3 0 ; 66.351 0.034475 4183900.0 14372.2 12138.2 10878.900000000001 13269.7 12248.0 11112.3 8045.5 8020.6 13250.3 8657.3 False True 14167.249792461324 12110.094743668791 9984.478835768412 14245.598004421532 11527.596720494492 10637.052833036492 8462.056623066159 8393.26635663985 11757.911682155276 10153.702769872854 1.3952791522021997 1.192677687946585 0.9833337711434149 1.4029953729480618 1.1353096482889111 1.0476033299495224 0.8333961329037527 0.8266212382682294 1.1579925026998312 1.0 13.309718313224137 -6.800797686497913 2.7307826163345954 0.9414894393864437 1.2237703562705287 0.44870492881388824 0.1417175910361091 0.25264001796255914 3.853183779031384 0.05383516444998167 0.04879288875669636 1.581984825867907e-07 6.800797686497913 0.28228091688408496 RLDDQES(ph)PVYAAQQR ddPTM_PC-9_AZD4547_30min_R2 1 RLDDQESPVYAAQQR 15 1 Q96ST3;H3BMA2;H3BT34;H3BQ76;H3BQ88;H3BNA0;H3BNZ3;H3BQL7;H3BP90 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 RLDDQES(1)PVYAAQQR 117.84 5.6072e-05 5609900.0 13283.0 11413.0 27798.0 55376.0 26902.0 36807.0 13341.0 27371.0 22891.0 33020.0 True False 17506.717696436415 15102.029056620739 27429.38035710946 42609.918750671415 23167.12166232153 34505.45247143986 14528.32315505847 23141.440873008578 24100.971527097274 31863.979850505777 0.5494203102867745 0.4739530067328053 0.8608271937717182 1.337244090367295 0.7270630276259668 1.082898389759437 0.4559481653961648 0.7262570771629852 0.7563704107324408 1.0 14.959638852062385 -5.265616854711112 23.816397901219013 0.8631870134037658 0.5116866283883513 0.2853659034608804 0.22563400547815093 226.13972472971383 1289274.632496386 0.061197059140209585 0.13543497583510555 5.4247926792415615e-06 5.265616854711112 -0.3515003850154145 RLDDQES(ph)PVYAAQQR ddPTM_PC-9_Lapatinib_30min_R1 1 RLDDQESPVYAAQQR 15 1 Q96ST3;H3BMA2;H3BT34;H3BQ76;H3BQ88;H3BNA0;H3BNZ3;H3BQL7;H3BP90 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 RLDDQES(1)PVYAAQQR 115.26 7.4618e-05 5775700.0 23745.0 17560.0 34086.0 17427.0 19098.0 21925.0 14919.0 13612.0 26889.0 13793.0 True False 23406.39194570031 17519.340898883176 31283.580655764996 18708.639714767796 17974.69318811266 20987.318859671283 15691.43282077237 14244.46321304911 23860.47766627723 16177.101671982757 1.4468841465117337 1.0829715516485288 1.9338186338993755 1.1564889739902808 1.1111195041348578 1.297347280447608 0.9699780058839885 0.8805324650780432 1.4749538050812507 1.0 13.98166553379385 -5.963476224118197 24.998165408951312 1.1189657904267714 1.4636920986520163 0.30589268447387086 0.24860797614118485 214.55285450617157 146846.2805734183 0.06813318718161895 0.10105756507710792 1.0877366852237823e-06 5.963476224118197 0.34472630822524497 RLDEEEEDNEGGEWER ddPTM_PC-9_AZD4547_30min_R2 1 RLDEEEEDNEGGEWER 16 1 Q99613-2;Q99613 Q99613-2 EIF3C Eukaryotic translation initiation factor 3 subunit C 0 79.471 0.0056248 19503000.0 11555.0 14733.0 18227.0 25883.0 21657.0 19589.0 12189.0 20809.0 19647.0 17702.0 False True 15229.249641069253 19495.1541304822 17985.298070689758 19916.0742383637 18650.29937703136 18364.096733312563 13273.79738677818 17593.447193249627 20685.50030985455 17082.258368069448 0.8915243706614412 1.1412515670014096 1.052864187109375 1.1658923433444426 1.0917935424681862 1.075039162716281 0.7770516696779314 1.0299251313360127 1.2109347525453873 1.0 14.060211099299016 -7.058024779273474 24.999950097205954 0.9954108285032786 1.0778425560295077 0.062450235795680986 0.11943620256272455 696.1110859462074 299916.5891325766 0.04620263736827068 0.03578846960272722 8.74933853239859e-08 7.058024779273474 0.08243172752622918 RLDEEEEDNEGGEWER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLDEEEEDNEGGEWER 16 1 Q99613-2;Q99613 Q99613-2 EIF3C Eukaryotic translation initiation factor 3 subunit C 0 125.39 2.0209000000000003e-05 16072000.0 25138.0 22525.0 23072.0 26233.0 30502.0 18003.0 24321.0 26663.0 24873.0 18826.0 False True 29393.366901868398 24761.133137461053 23622.12398104725 24763.2500585335 24525.352060439098 17058.89098752979 22017.138811208293 25963.124501783706 25236.720569907055 22239.004773465986 1.3217033406521184 1.1134101273724395 1.0621933949684432 1.1135053169321347 1.1028079858007414 0.7670707912200845 0.9900235660490344 1.1674589203182815 1.1347954113494203 1.0 14.440804606436773 -1.5228832511486727 0.8872577627122692 1.0326808902678504 132.92016717801062 0.3901066288876306 0.10607669288209401 948.352037742829 2.2268493528920836 0.0391648871234158 253066.63777491014 0.02999968874725686 1.5228832511486727 131.88748628774277 RLDEEEEDNEGGEWER ddPTM_PC-9_Lapatinib_30min_R1 1 RLDEEEEDNEGGEWER 16 1 Q99613-2;Q99613 Q99613-2 EIF3C Eukaryotic translation initiation factor 3 subunit C 0 58.658 0.033309 23448000.0 42990.0 34556.0 34898.0 25564.0 28111.0 27052.0 23302.0 23527.0 35501.0 26465.0 False True 42376.95471659954 34475.98770511429 32028.82115017567 27444.061839004054 26457.566248352414 25895.049021292034 24508.463542438334 24620.150309536162 31502.50353789686 31039.439987604135 1.3652615747424288 1.1107155193161529 1.0318749682006716 0.8841674285993586 0.8523854250888053 0.8342627647803389 0.7895910348970857 0.7931892559713845 1.0149185536362013 1.0 14.921814908260231 -4.761839905271806 0.9672337748947112 0.8610573203890507 1.6381784538191384 0.7928126136914175 0.07699882728542135 0.8627269564664957 0.623063839985431 0.025667521461120446 0.711955489793996 1.730454141966408e-05 4.761839905271806 0.7771211334300877 RLDEELEDAEK ddPTM_PC-9_Lapatinib_30min_R1 1 RLDEELEDAEK 11 1 Q15008;Q15008-4;C9J7B7;C9J0E9;Q15008-3;Q15008-2 Q15008 PSMD6 26S proteasome non-ATPase regulatory subunit 6 0 182.71 0.00092924 3715100.0 20237.0 33450.0 32553.0 23165.0 28856.0 27151.0 28052.0 30591.0 29128.0 26743.0 False True 19948.416668988717 33372.548580161885 29876.61799821388 24868.63137617466 27158.746813078786 25989.81502207229 29504.395300509845 32012.369537936036 25847.297908562003 31365.491917192416 0.6359988461731844 1.0639893252198394 0.9525314660165608 0.7928659764632411 0.8658798301260571 0.8286117460133456 0.940664198042995 1.020623863399032 0.824067990924583 1.0 14.936890568722212 -7.352423096430114 7.169629585303191 0.9489004519394013 0.8680610470387824 0.12481498468788721 0.11400110226317989 0.67195807645656 46.02231154644353 0.047219323244647594 0.031685359406947146 4.441983117122915e-08 7.352423096430114 -0.08083940490061892 RLDEVSR ddPTM_PC-9_AZD4547_30min_R2 2 RLDEVSR 7 1 Q9P2E9;A0A087WVV2;Q9P2E9-3;F8W7S5 Q9P2E9 RRBP1 Ribosome-binding protein 1 0 ; 122.74 0.0031980999999999997 3781700.0 6286.6 6557.0 9323.0 14046.8 8458.2 8789.7 5430.0 9789.8 7704.099999999999 8336.0 False True 8285.608030596795 8676.42202087638 9199.370928460019 10808.527280896618 7283.924929159467 8240.07866949805 5913.259480696158 8277.01135722405 8111.322997768126 8044.159177280924 1.0300154246074336 1.0785989970687244 1.1436087632927197 1.343649105231916 0.9054923912658787 1.0243554966901278 0.7350997600093425 1.0289467394679073 1.0083493897879212 1.0 12.973725914540273 -6.300565064105784 24.953014836442655 0.9447566339412568 1.1435590464978325 0.4337586713321854 0.1109799754004651 514.6818405543609 328245.029534958 0.0352122793937212 0.039927551796522576 5.005355588562217e-07 6.300565064105784 0.1988024125565757 RLDEVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RLDEVSR 7 1 Q9P2E9;A0A087WVV2;Q9P2E9-3;F8W7S5 Q9P2E9 RRBP1 Ribosome-binding protein 1 0 ; 124.08 0.0029444000000000002 2497900.0 5937.5 5669.700000000001 4987.5 10459.4 9314.2 6120.4 5359.7 6799.799999999999 5149.0 2249.01 False True 6942.601479029505 6232.550346258071 5106.42091519908 9873.39372783232 7489.1493725441505 5799.435449651575 4851.990415132318 6621.312454983636 5224.294384049031 2656.7377098466372 2.613205456187195 2.345941160528734 1.9220643785320655 3.716359989636414 2.818926890971284 2.1829160734073194 1.8262963623203903 2.492271792749107 1.9664321263955742 1.0 11.375440087431349 -8.897189676802968 0.4990693240981182 0.9341286793823401 2.629612373128466 0.4871952365146579 0.4853371545542369 1.5547621646261083 0.772175419752362 0.7722597695630045 0.2803098589246731 1.2670983436183878e-09 8.897189676802968 1.6954836937461262 RLDEVSR ddPTM_PC-9_Lapatinib_30min_R1 2 RLDEVSR 7 1 Q9P2E9;A0A087WVV2;Q9P2E9-3;F8W7S5 Q9P2E9 RRBP1 Ribosome-binding protein 1 0 ; 101.6 0.0070531000000000005 4109300.0 10998.1 8864.2 8259.9 6587.4 6608.5 9159.7 6431.9 8578.7 8752.5 6541.1 False True 10841.265077195472 8843.675489514826 7580.8029061360485 7071.859370922213 6219.801022810893 8767.960983303583 6764.912310471597 8977.29772008407 7766.701282089014 7671.72041953211 1.4131465283319944 1.1527630056745723 0.9881490059042576 0.9218087970095133 0.8107439638930731 1.1428937062122932 0.8817985980365252 1.1701805109096488 1.0123806470208538 1.0 12.90533442984815 -4.85129128655904 2.196689030563721 0.9896529954387423 1.4875792038100601 0.6165562221278122 0.1027272391604328 0.3608789088308404 2.306533936046427 0.027628064485677378 0.33793214823735546 1.408343888305136e-05 4.85129128655904 0.49792620837131785 RLDLPIER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLDLPIER 8 1 B4E1E0;P17812-2;P17812;A0A3B3IRI2;A0A3B3ISY3;A0A3B3ITB8;A0A3B3IRQ8;A0A3B3ITF6 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 0 91.265 0.0056029 2294200.0 6746.4 8429.0 7930.3 8817.0 10977.0 10454.0 11002.0 11134.0 7517.3 7046.8 False True 7888.432272526253 9265.775414679656 8119.388427830226 8323.01207509968 8826.13564905383 9905.773836784789 9959.810912417823 10841.744297448138 7627.226291165617 8324.329057561892 0.94763580559809 1.1130957643081811 0.975380522764715 0.9998417911578091 1.060281926389742 1.1899786479231378 1.1964701111100653 1.3024165938754433 0.9162571828220774 1.0 13.023118280048843 -6.575817384536836 4.986581343324244 1.144133833021527 1.0154793094281516 0.17437915907727475 0.10893922812701709 0.29340788323424416 15.616045905501108 0.03532268433146405 0.03570033218939413 2.6557220255251177e-07 6.575817384536836 -0.12865452359337537 RLDLPIER ddPTM_PC-9_Lapatinib_30min_R1 1 RLDLPIER 8 1 B4E1E0;P17812-2;P17812;A0A3B3IRI2;A0A3B3ISY3;A0A3B3ITB8;A0A3B3IRQ8;A0A3B3ITF6 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 0 112.11 0.0023636 4105200.0 11725.0 13378.0 15996.0 10751.0 13283.0 12266.0 11875.0 11461.0 10701.0 9872.5 False True 11557.799349898338 13347.024062941864 14680.870626345624 11541.664404284642 12501.720055382775 11741.411773442562 12489.82939517876 11993.519900437534 9495.740693474387 11578.948470720645 0.9981734851937734 1.1526974229734332 1.26789325157364 0.9967800127507017 1.0796939019977088 1.0140309202629871 1.078666981441487 1.0358038927943416 0.8200866181835073 1.0 13.499216622085704 -7.418077353370834 0.7577669467446738 0.9342444390562887 1.1162221384148738 0.3189877429287715 0.09107018089162001 0.8149997896041178 0.8950563350180251 0.08015498660640401 0.044924942950101285 3.8187624776569e-08 7.418077353370834 0.1819776993585851 RLDPDAIPS(ph)PQLSELPPQQK ddPTM_PC-9_AZD4547_30min_R2 1 RLDPDAIPSPQLSELPPQQK 20 1 A0A0U1RR49 A0A0U1RR49 1 RLDPDAIPS(0.999)PQLS(0.001)ELPPQQK 72.64399999999999 0.0014676 4128600.0 17092.0 16927.0 19889.0 28268.0 21920.0 18799.0 17758.0 26815.0 19054.0 22589.0 True False 22526.900464314647 22398.32172447376 19625.258864758267 21751.249336246387 18876.78636674181 17623.49555819811 19338.427598195653 22671.35789739962 20061.15554048805 21798.165985556487 1.0334309996190056 1.0275323960426275 0.9003169751878212 0.9978476790505593 0.8659804856633173 0.8084852445786254 0.8871584706258929 1.0400580449025716 0.9203139178672469 1.0 14.411919136806311 -5.252182922477598 23.477664583994386 0.9235718705372697 1.0304817459848146 0.2795890280800437 0.06586624394451274 383.44816343301676 972546.4229079479 0.01790796107747899 0.04584421332748434 5.595218842776846e-06 5.252182922477598 0.10690987544754482 RLDPDAIPS(ph)PQLSELPPQQK ddPTM_PC-9_Lapatinib_30min_R1 2 RLDPDAIPSPQLSELPPQQK 20 1 A0A0U1RR49 A0A0U1RR49 1 RLDPDAIPS(0.992)PQLS(0.008)ELPPQQK;RLDPDAIPS(0.97)PQLS(0.03)ELPPQQK 58.997 0.007423300000000001 7206700.0 110905.0 80485.0 102818.0 77575.0 84421.0 80403.0 82182.0 81336.0 93695.0 71530.0 True False 109323.47436251375 80298.64192748375 94364.70092895748 83280.12428261389 79455.5227580719 76964.35111854732 86436.98184038562 85115.1674916665 83142.08244790976 83893.86519226611 1.3031164330308136 0.9571455760615761 1.1248105056632514 0.992684317163768 0.9470957450342463 0.917401420737525 1.030313499590122 1.0145577068907417 0.9910388829667888 1.0 16.35627769581297 -4.756693214154156 24.999986594500765 0.998500183748507 1.3031168936798598 0.7487988447168772 0.05314661173104639 75.91958007720227 399852.01047037094 0.013816170220870725 0.10931794251354136 1.7510832179183866e-05 4.756693214154156 0.3046167099313528 RLDQLER ddPTM_PC-9_Lapatinib_30min_R1 1 RLDQLER 7 1 M0R2F5;Q96CT7 M0R2F5 CCDC124 Coiled-coil domain-containing protein 124 0 97.635 0.0078595 1628400.0 6686.2 5813.4 5777.2 4550.2 6999.9 8260.6 8129.9 5874.0 6088.4 4929.8 False True 6590.853561901086 5799.93942947423 5302.220916636904 4884.836887022232 6588.179644332898 7907.313394399118 8550.82644209379 6146.927484091274 5402.6602783057115 5781.909361454409 1.1399095263996306 1.003118358814135 0.9170363257481362 0.8448484024304174 1.1394470636730416 1.3675955294480913 1.4788932007648896 1.0631310696549983 0.93440763951144 1.0 12.497330277633885 -6.466624926048117 8.239329514377932 1.1988597323436452 0.9755636898345531 0.22188383406157763 0.16825283097226015 0.49618174021743017 67.78493252492795 0.0566466207924995 0.0639361898475506 3.414877066424972e-07 6.466624926048117 -0.22329604250909207 RLDS(ph)SGER ddPTM_PC-9_AZD4547_30min_R2 1 RLDSSGER 8 1 A0A087X2H1;Q9ULT8;A0A087WVU6;G3V4V5 A0A087X2H1 HECTD1 E3 ubiquitin-protein ligase HECTD1 1 RLDS(0.955)S(0.045)GER 81.625 0.016853 0.0 20663.0 18009.0 24680.0 36919.0 26132.0 25044.0 20082.0 23806.0 28173.0 30543.0 True False 27233.404182900373 23830.057064810535 24352.72707437448 28407.894942864008 22504.02287115405 23477.994720969924 21869.259096011112 20127.32970745835 29662.167263680563 29473.698866565646 0.923990039600811 0.8085193912272362 0.8262528291621962 0.9638388134272938 0.7635289677429035 0.7965744247866655 0.7419923503669621 0.6828912040724681 1.0063944602938422 1.0 14.847140505555629 -4.753430263414716 24.53721312186297 0.8295329963586848 0.9239902599267961 0.0352204177463864 0.10650790725001553 728.5688260542512 2231860.703526298 0.0257332635335221 0.27401200910841417 1.764289041424849e-05 4.753430263414716 0.09445726356811124 RLDS(ph)SGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLDSSGER 8 1 A0A087X2H1;Q9ULT8;A0A087WVU6;G3V4V5 A0A087X2H1 HECTD1 E3 ubiquitin-protein ligase HECTD1 1 RLDS(0.986)S(0.014)GER 79.036 0.018838999999999998 0.0 38112.0 29905.0 32820.0 33233.0 45517.0 41492.0 37681.0 44383.0 49241.0 37351.0 True False 44563.608853687954 32873.77076474018 33602.553270543125 31371.062752839716 36598.270596518465 39316.08647750854 34111.58289318448 43217.993277675625 49961.056470180294 44122.440629646706 1.0099987266739008 0.745057850282463 0.7615751257414561 0.7110001691919305 0.8294706746554584 0.891067808499499 0.7731118770040173 0.9795014206135423 1.1323275810951063 1.0 15.429224975258933 -7.913667425564569 4.097522400713578 1.0648632440668435 0.8119881159525777 0.5884469479446618 0.08598703394470465 0.14524478748123112 4.534484960178022 0.05206644737602693 0.02298173481313265 1.2199234354339964e-08 7.913667425564569 -0.2528751281142658 RLDS(ph)SGER ddPTM_PC-9_Lapatinib_30min_R1 2 RLDSSGER 8 1 A0A087X2H1;Q9ULT8;A0A087WVU6;G3V4V5 A0A087X2H1 HECTD1 E3 ubiquitin-protein ligase HECTD1 1 RLDS(0.83)S(0.17)GER;RLDS(0.986)S(0.014)GER 79.23 0.018690000000000002 14254000.0 45057.0 45289.6 34835.6 43499.2 61206.3 42081.2 50379.6 60242.4 61232.2 52453.1 True False 44414.47891755816 45184.734713784725 31971.551437304697 46698.27627707734 57606.265770215694 40281.48517206838 52988.00917872397 63041.48182969361 54335.58483234855 61519.548445637585 0.7219571671077121 0.7344776718202459 0.519697433500454 0.759080283535286 0.9363896066486914 0.6547753712409569 0.8613198652709131 1.0247390207260851 0.883224701825677 1.0 15.90875729348589 -7.191123972242783 0.621572230953309 0.9982265651149252 0.671005621530811 0.525101308474192 0.10464761065654876 0.6539651672537422 0.5180765240560462 0.09581961457450913 0.0727667170624998 6.439854093649535e-08 7.191123972242783 -0.32722094358411424 RLDSDAVNTIESQS(ph)VSPDHNKEPK ddPTM_PC-9_Lapatinib_30min_R1 1 RLDSDAVNTIESQSVSPDHNKEPK 24 2 Q3T7B4;Q9H3H1-6;Q9H3H1-3;Q9H3H1-2;Q9H3H1-5;Q9H3H1-4;Q9H3H1 Q3T7B4 TRIT1 tRNA dimethylallyltransferase, mitochondrial 1 RLDSDAVNTIES(0.05)QS(0.475)VS(0.475)PDHNKEPK 70.072 0.00024669 6067400.0 50548.0 43438.0 43068.0 42452.0 46612.0 37812.0 34180.0 37857.0 42333.0 29416.0 True False 49827.17625063207 43337.42197982274 39527.11528728768 45574.06169572057 43870.3738027179 36194.868904077106 35949.673155975564 39615.97442377315 37565.01175374743 34500.516405643786 1.4442443604258939 1.2561383566053916 1.1456963374850127 1.3209675229169995 1.27158600430518 1.0491109315151048 1.04200391476154 1.148271926077389 1.0888246225671665 1.0 15.074330335941289 -6.75569925020312 24.13771172916135 1.0734318613597023 1.2799278397115963 0.6710448456795297 0.07755464851512217 60.84308772746382 255849.55252343847 0.026626857708213977 0.025914547066410783 1.7550954882370208e-07 6.75569925020312 0.20649597835189404 RLEAAYLDLQR ddPTM_PC-9_AZD4547_30min_R2 1 RLEAAYLDLQR 11 1 E5RIW3;E5RJD8;E5RHG6;O75347;O75347-2 E5RIW3 TBCA Tubulin-specific chaperone A 0 130.56 0.00012828 4490500.0 18624.0 16558.0 22227.0 28587.0 28906.0 20395.0 16532.0 22467.0 21910.0 20691.0 False True 24546.044596735057 21910.049690662043 21932.255457136205 21996.708814747246 24892.9008538795 19119.697425897673 18003.31597327236 18995.241390299358 23068.117869848487 19966.614387850244 1.2293543672417198 1.097334243305384 1.0984463881108486 1.10167444452337 1.2467261785266368 0.9575833466054253 0.9016709404788947 0.9513501398543576 1.1553344709198932 1.0 14.285302104422257 -6.778818340533369 24.998937003978625 0.9844273232059847 1.1454478955621636 0.5101215521030387 0.07864660504827264 210.62839584973722 302978.6109611001 0.028256770405896914 0.024977615620595785 1.6641085787644538e-07 6.778818340533369 0.16102057235617895 RLEEEADR ddPTM_PC-9_AZD4547_30min_R2 4 RLEEEADR 8 1 A0A669KAX4;Q13620-1;Q13620;Q13620-3;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 0 ;;; 140.11 0.0016245 10642300.0 45185.0 45996.2 62007.0 76149.0 71183.0 64892.0 60780.0 70950.0 54218.0 59976.0 False True 59552.89009361441 60863.57214528506 61184.746665345934 58594.0245403221 61300.4691580192 60834.29298167943 66189.30225353816 59986.307768804945 57083.85279175925 57876.25849527364 1.028969246491248 1.0516155281574633 1.057164859237445 1.0124017354215644 1.0591643404700253 1.0511096356832974 1.1436347817636379 1.036457941967752 0.9863086224970969 1.0 15.820684039069626 -8.121206434056017 4.965439964875822 0.9948498147191538 1.0575972881935678 0.37873776734616404 0.032466936092895325 0.2489822995964074 8.817461455965441 0.02427053942424361 0.008738706653357986 7.564732336284542e-09 8.121206434056017 0.062747473474414 RLEEEADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RLEEEADR 8 1 A0A669KAX4;Q13620-1;Q13620;Q13620-3;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 0 ;;; 101.46 0.0028975999999999997 10920300.0 48997.5 55176.0 59231.0 63276.0 67629.0 54692.0 65642.0 59983.0 54782.0 49938.2 False True 57291.80900526284 60653.508634519465 60643.29167481838 59730.85086355987 54377.58292883857 51823.8552402366 59423.91455307487 58408.509807241935 55583.08311263814 58991.60034942631 0.9711858750382247 1.0281719477900095 1.0279987543244897 1.0125314537960444 0.9217851796991873 0.878495496532848 1.0073284027062805 0.9901157022570918 0.942220295489554 1.0 15.848221927296459 -6.2372596810951535 23.354198133389144 0.9547887447583285 1.0125596522315308 0.3066825325120456 0.03913339854646078 432.19902485916873 417442.4954708754 0.01224180759027019 0.015792943387706468 5.790823376569095e-07 6.2372596810951535 0.05777090747320224 RLEEEADR ddPTM_PC-9_Lapatinib_30min_R1 2 RLEEEADR 8 1 A0A669KAX4;Q13620-1;Q13620;Q13620-3;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 0 ; 122.33 0.0021093 5216200.0 33855.7 38520.0 40684.0 35953.0 43418.6 41916.0 34288.4 33811.4 42946.0 27571.0 False True 33372.911509625 38430.80930666176 37339.11856478154 38597.10355569213 40864.803312251934 40123.35039096836 36063.68557757028 35382.40107858423 38108.96923857124 32336.61061395177 1.0320472948771606 1.1884612696570191 1.1547010603724626 1.1936038695112727 1.263731805417499 1.2408025958557625 1.1152586771728774 1.0941901580531865 1.1785084619267105 1.0 14.980880849124748 -10.774428525707467 2.8252036294460874 0.9987280764411074 1.1657254467430125 0.3580664295583694 0.06508066800484429 5689828.686195743 6995056.920365259 62465.84591614988 0.017617656808495977 1.6810145569921646e-11 10.774428525707467 0.1669973703019051 RLEEELR ddPTM_PC-9_Lapatinib_30min_R1 2 RLEEELR 7 1 Q07065 Q07065 CKAP4 Cytoskeleton-associated protein 4 0 ; 116.9 0.0048035 2324700.0 18950.0 26633.2 13438.5 8025.3 11007.4 11680.9 14596.2 11461.2 18100.3 8946.5 False True 18679.7695249956 26571.532461738934 12333.638404110141 8615.507333615991 10359.966373381041 11181.335136507843 15351.919816244888 11993.729193167668 16061.653609391129 10492.890604538086 1.7802310372812578 2.532336747154018 1.1754280940254869 0.8210804494511605 0.987331972078356 1.0656105698530784 1.4630782302833991 1.1430338545586745 1.5307177225734727 1.0 13.357124549014983 -5.2764203496538045 24.72808640995588 1.1442491415207239 2.156283842619182 0.7017539262719746 0.26284367163984806 314.2098072332506 518645.1687040454 0.06870084575006224 0.14395313977833896 5.291510355101796e-06 5.2764203496538045 1.0120347010984583 RLEELER ddPTM_PC-9_AZD4547_30min_R2 1 RLEELER 7 1 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;H7C3Z6;F6V107;Q9NRD5-2;Q9NRD5;O95819-6;E7EN19 C9J840;O95819-6;E7EN19 MAP4K4;PICK1 PRKCA-binding protein 0 79.71300000000001 0.045811000000000004 0.0 2330.1 3814.5 6268.2 8134.7 5886.6 6239.6 4954.8 5893.8 3998.4 5860.5 False True 3071.023330909172 5047.462528386909 6185.079572430879 6259.370594862153 5069.347200112334 5849.436825625457 5395.7676012805405 4983.048636050488 4209.747261104615 5655.32567879737 0.5430320914006563 0.8925149169234537 1.0936734546729348 1.1068099257889663 0.8963846625346523 1.034323601831781 0.9541037789406276 0.8811249641612428 0.7443863537139097 1.0 12.465394393166594 -4.782278174458602 3.8814620241832376 0.966026581166007 0.5029690088332867 0.6030865731484512 0.10181543679799591 0.1714013510197011 4.70714473471526 0.027283953307475246 0.22510574549474013 1.6509040218604316e-05 4.782278174458602 -0.4630575723327204 RLEEPEEPKVLT(ph)PEEQLADK ddPTM_PC-9_AZD4547_30min_R2 1 RLEEPEEPKVLTPEEQLADK 20 2 O75822;O75822-2 O75822 EIF3J Eukaryotic translation initiation factor 3 subunit J 1 RLEEPEEPKVLT(1)PEEQLADK 50.117 0.024384 4816300.0 29220.0 22297.0 26666.0 33515.0 36028.0 31058.0 27227.0 29514.0 26940.0 29833.0 True False 38511.3521862435 29504.069208400284 26312.39141674513 25788.63455158828 31026.13408854807 29115.93835025889 29650.150254312044 24953.289464249578 28363.993400899963 28788.555750458472 1.3377313026767654 1.0248540935552286 0.9139878931344477 0.8957946614316552 1.0777245776927855 1.0113719702592308 1.0299283684573115 0.8667780933696955 0.9852523914975572 1.0 14.813207793879235 -4.769785706995586 3.8193611802054512 0.9719844815419261 1.3789280531230874 0.7602412320153797 0.061140159574548825 0.12774073247325557 3.3229539584979184 0.016109138846517542 0.1492711719414235 1.699081819993257e-05 4.769785706995586 0.40694357158116135 RLEEPEEPKVLT(ph)PEEQLADK ddPTM_PC-9_Lapatinib_30min_R1 1 RLEEPEEPKVLTPEEQLADK 20 2 O75822;O75822-2 O75822 EIF3J Eukaryotic translation initiation factor 3 subunit J 1 RLEEPEEPKVLT(1)PEEQLADK 62.735 0.0044727 4454800.0 22941.0 24271.0 26447.0 25400.0 26095.0 21824.0 25568.0 25592.0 25922.0 22360.0 True False 22613.857133135833 24214.801990705804 24272.629748372256 27268.000731916105 24560.143404743932 20890.638394228798 26891.785934815187 26781.097748189295 23002.391389238674 26224.896207172806 0.8623049240877715 0.9233516807621447 0.9255567517454432 1.0397753537898846 0.9365201376097899 0.7965956558682193 1.0254296422137976 1.0212089129589905 0.8771203976375418 1.0 14.678649442468545 RLEEQAAQHK ddPTM_PC-9_AZD4547_30min_R2 4 RLEEQAAQHK 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ;;; 86.898 0.0043536 10648000.0 56001.0 56567.0 62965.0 81075.0 70649.0 61166.0 56603.0 64923.0 60659.0 63156.0 False True 73808.15310683862 74851.1765220245 62130.04295939983 62384.411346263376 60840.60584050835 57341.2803506966 61640.55734545943 54890.64213212293 63865.31090219713 60944.9276631903 1.2110631013418611 1.2281772969800953 1.019445675655881 1.0236194173701925 0.998288260784253 0.9408704308845994 1.0114140701932324 0.9006597306255553 1.047918397001736 1.0 15.895218532475695 -5.315879874684524 3.4785790883006684 0.9859551400903931 1.2246802079409955 0.8367119522428328 0.04016406456904229 0.0802142418578897 1.9472213815594157 0.010511342147101296 0.026400013319022777 4.831924339861288e-06 5.315879874684524 0.23872506785060243 RLEEQAAQHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RLEEQAAQHK 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ;;; 93.556 0.0026658000000000003 7977600.0 52566.3 55822.0 57084.0 60902.0 70422.0 65732.0 58848.0 59238.0 65390.0 55529.3 False True 61464.73635824984 61363.63924525422 58445.099052275575 57489.85838694802 56623.31462855684 62284.89820542734 53273.49141737535 57683.065267849175 66346.2050442738 65596.32252030312 0.9370149727406671 0.9354737718148939 0.8909813356409709 0.8764189237766185 0.8632086747093332 0.9495181408401234 0.8121414337044024 0.8793643157357691 1.0114317768917394 1.0 16.00132731588004 -8.263557974644055 24.99266548634944 1.0057159059003473 0.8920035648299511 0.5768786241594912 0.0386001792971293 138.88896360851118 1638385.3315900387 0.03253340095860123 0.010030355531055756 5.4505713031043445e-09 8.263557974644055 -0.11371234107039618 RLEEQAAQHK ddPTM_PC-9_Lapatinib_30min_R1 4 RLEEQAAQHK 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ;;; 105.2 0.00099015 9092900.0 77746.0 80828.0 78605.0 67586.0 79158.0 77375.0 66477.0 69847.0 86679.0 62929.0 False True 76637.32778312992 80640.8477320576 72142.4003240748 72556.49990028676 74502.08207061587 74065.85161993463 69918.8537855409 73092.34660900976 76916.29824966505 73806.19380237824 1.0383590297087024 1.0926027149967885 0.9774572648637271 0.9830678993495093 1.0094285890165386 1.0035181033485028 0.9473304364231815 0.9903280855360207 1.042138800106863 1.0 16.17145427162131 -5.267199851382892 24.967331151270205 0.9926243076891145 1.0654808737830181 0.5458313550295553 0.025993280752982288 300.5330713820996 1302590.877374655 0.006807778471356096 0.014820249117273959 5.405055386715447e-06 5.267199851382892 0.07285656609390367 RLEIS(ph)PDSS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 1 RLEISPDSSPER 12 1 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 2 RLEIS(0.999)PDS(0.125)S(0.876)PER 106.76 0.009426100000000001 12332000.0 62415.0 53979.0 55978.0 39318.0 48679.0 48529.0 35774.0 39925.0 49219.0 35641.0 True False 61524.950654490785 53854.01494195985 51375.70492132881 42209.576881003064 45815.79692659627 46453.527796624294 37626.202676473644 41780.06125337832 43675.4379209528 41801.49936135271 1.4718359770456764 1.2883273510459343 1.2290397642728546 1.0097622699157924 1.0960323822488278 1.1112885543902902 0.9001161023248054 0.9994871449995353 1.0448294579914668 1.0 15.351267070238228 -4.1984250258507645 0.5585293667404071 0.9952826673265037 2.1860048894471533 0.865056500281991 0.05917530637698268 2.458295036647802 0.36135389718799893 0.03166695761463613 2.1862515573829575 6.332496729260947e-05 4.1984250258507645 1.1907222221206495 RLEIS(ph)PDSSPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLEISPDSSPER 12 1 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 RLEIS(0.404)PDS(0.298)S(0.298)PER 131.08 0.00038306 0.0 20706.0 21255.0 26838.0 29595.0 37554.0 31103.0 37358.0 29193.0 23579.0 23047.0 True False 24211.116837858495 23365.05593059866 27477.919703681797 27936.888098284555 30195.563283644675 29471.903926297804 33819.179791502 28426.714682540296 23923.79826791455 27225.2386600484 0.8892894251607436 0.8582130802359373 1.009281132363559 1.0261393278171869 1.1091018764127518 1.0825214167744384 1.2421995712797869 1.0441309638271417 0.8787360348477481 1.0 14.732657075402894 -5.441090367440525 2.056957446775533 1.0694311928727427 0.86686447232033 0.3910694608905685 0.08731677661881525 0.340922611836589 2.758166334456049 0.026475714880055873 0.07585165756858767 3.621676311981648e-06 5.441090367440525 -0.20256672055241265 RLEIS(ph)PDSSPER ddPTM_PC-9_Lapatinib_30min_R1 1 RLEISPDSSPER 12 1 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 RLEIS(0.906)PDS(0.083)S(0.011)PER 137.39 9.7363e-05 17996000.0 33203.0 30760.0 29104.0 22952.0 34016.0 25382.0 22981.0 28245.0 36859.0 24308.0 True False 32729.519131315545 30688.77710988876 26711.181464688856 24639.966645627486 32015.245758029123 24296.47102833189 24170.843733103407 29557.365813441953 32707.551277522885 28509.605411625962 1.1480172615075457 1.0764364033384395 0.9369186657980287 0.8642689468995431 1.1229634818086116 0.8522205298016509 0.8478140396586041 1.0367511365621611 1.1472467193174494 1.0 14.799160451283052 -5.059281238129021 3.6720370017929813 0.9700163962138239 1.1385740402006699 0.23714348294870147 0.10080259865640784 0.3214361389607406 8.415381544923825 0.027048585745103642 0.097802707259226 8.724062371977212e-06 5.059281238129021 0.16855764398684603 RLES(ph)SGAGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLESSGAGGR 10 1 Q15773 Q15773 MLF2 Myeloid leukemia factor 2 1 RLES(0.983)S(0.017)GAGGR 81.23899999999999 0.024322999999999997 4982300.0 17055.0 14269.0 19394.0 16903.0 27929.0 21687.0 21814.0 26290.0 20535.0 14243.0 True False 19942.07464839547 15685.532019464232 19856.426512154587 15955.97971026538 22456.51294000403 20549.695542218436 19747.620000316503 25599.91535655752 20835.285526596774 16825.143152474026 1.1852543819493817 0.9322673737345158 1.1801638971038906 0.9483413939285954 1.3346996656430796 1.221368243704764 1.1736969974851446 1.5215273430106433 1.2383422439727108 1.0 14.038331159243038 -6.269466276718258 24.807370014558575 1.2692748063634567 1.0607508846878826 0.2768865573593624 0.14550332431593596 632.4814843538192 1954700.8836478116 0.04292847360285767 0.04955043980238329 5.376921836895873e-07 6.269466276718258 -0.2085239216755741 RLFDANK ddPTM_PC-9_Lapatinib_30min_R1 1 RLFDANK 7 1 P06744-2;P06744;A0A2U3TZU2;A0A0J9YXP8;A0A2R8Y6C7;A0A0J9YYH3;A0A0J9YX90;K7EPY4;K7ERC6;K7EP41;K7ENA0;A0A0J9YYI8;K7EIL4;A0A0J9YXM3;K7ELR7;A0A2R8YF08;K7ERK8;A0A0J9YXH9 P06744-2 GPI Glucose-6-phosphate isomerase 0 79.71300000000001 0.045811000000000004 0.0 25139.0 24064.0 26727.0 22038.0 23391.0 22506.0 24845.0 22893.0 23981.0 22292.0 False True 24780.513250072014 24008.281286487756 24529.60922920354 23658.748036612877 22015.187368475377 21543.470844048436 26131.35253248135 23956.692355005376 21280.00724887479 26145.14249777712 0.9478056297524051 0.9182692841903217 0.9382090471026908 0.9049003285648323 0.8420373830568001 0.8239951587902066 0.9994725610963129 0.9162961095753137 0.813918197259167 1.0 14.674255312816099 -4.417893580385887 0.002284363648026158 1.8030766333074082 1.1597362454922322e-07 0.01651549277998643 0.06249289645468098 1494894.8707339205 479.20596932613876 185638.08163858528 192654.02715420214 3.820378740148802e-05 4.417893580385887 -1.8030765173337837 RLFDDEAS(ph)VDEPR ddPTM_PC-9_AZD4547_30min_R2 4 RLFDDEASVDEPR 13 1 A0A0U1RR46;A0A0X1KG69;A0A087WUZ6;A0A2R8Y549;Q8NI35-4;Q8NI35-3;Q8NI35-2;Q8NI35;Q8NI35-5 A0A0U1RR46 INADL InaD-like protein 1 RLFDDEAS(1)VDEPR;RLFDDEAS(1)VDEPR;RLFDDEAS(1)VDEPR;RLFDDEAS(1)VDEPR 189.04 3.6697e-05 47863000.0 91003.0 85791.0 136612.0 180325.0 156866.0 145303.0 116978.0 153523.0 121074.0 130430.0 True False 119940.06102001062 113521.26301555677 134800.43561930498 138753.85724347777 135087.86360425744 136217.18044006906 127388.81538358679 129799.54795757915 127473.72446253017 125863.68539980249 0.9529361915553669 0.9019381774414093 1.071003404922676 1.1024137486736545 1.073287049995037 1.08225958907352 1.0121173154825378 1.0312708351521291 1.0127919268978454 1.0 16.941502566462084 -5.263260495590497 24.995512505233794 1.0520278644599879 0.9274371784143987 0.6621054592159898 0.034402302528897345 89.86800983948886 1233491.696128306 0.009504264276221582 0.02156783350624012 5.454306064431962e-06 5.263260495590497 -0.1245906860455892 RLFDDEAS(ph)VDEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RLFDDEASVDEPR 13 1 A0A0U1RR46;A0A0X1KG69;A0A087WUZ6;A0A2R8Y549;Q8NI35-4;Q8NI35-3;Q8NI35-2;Q8NI35;Q8NI35-5 A0A0U1RR46 INADL InaD-like protein 1 RLFDDEAS(1)VDEPR;RLFDDEAS(1)VDEPR;RLFDDEAS(1)VDEPR 145.46 6.824600000000001e-05 26675800.0 48725.0 39772.0 50750.0 54233.0 64114.0 55416.0 45671.0 53477.0 54036.0 36890.8 True False 56973.18013738313 43720.30131600893 51960.072470446794 51194.5008357583 51551.321946200005 52509.88740570744 41344.712250593926 52073.28541356512 54826.174273931516 43578.81001258791 1.307359703510174 1.0032467913506622 1.1923242616179268 1.174756741199922 1.1829446910392736 1.204940827676106 0.9487343100615034 1.1949221513511625 1.2580925054652654 1.0 15.411339181501715 RLFDDEAS(ph)VDEPR ddPTM_PC-9_Lapatinib_30min_R1 5 RLFDDEASVDEPR 13 1 A0A0U1RR46;A0A0X1KG69;A0A087WUZ6;A0A2R8Y549;Q8NI35-4;Q8NI35-3;Q8NI35-2;Q8NI35;Q8NI35-5 A0A0U1RR46 INADL InaD-like protein 1 RLFDDEAS(1)VDEPR;RLFDDEAS(1)VDEPR;RLFDDEAS(1)VDEPR;RLFDDEAS(1)VDEPR;RLFDDEAS(1)VDEPR 163.91 0.00049392 66781000.0 135693.4 117326.1 135463.1 109887.1 129383.2 123368.9 99043.2 102155.3 127817.5 91215.8 True False 133758.38723287787 117054.4386239439 124325.84682068758 117968.56390661951 121773.1345531582 118092.69973395215 104171.17227390039 106901.80817425784 113421.34717205515 106982.32949258671 1.2502848635591413 1.0941474090079066 1.1621157195806124 1.1026920470524442 1.138254655051201 1.1038523865956325 0.9737231631427401 0.9992473400167039 1.0601876750114572 1.0 16.707012997617632 -7.086333702751106 3.826983678580297 1.0087403742520304 1.143350417046541 0.6869252584017687 0.044871343226021806 0.14127870431270534 3.8334869816315322 0.017303211071337327 0.013405228686753801 8.197214455551189e-08 7.086333702751106 0.1346100427945105 RLGDS(ph)SLSR ddPTM_PC-9_AZD4547_30min_R2 2 RLGDSSLSR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 RLGDS(0.67)S(0.33)LSR;RLGDS(0.698)S(0.302)LSR 89.561 0.0042408 46619000.0 30136.0 21244.4 55075.0 77982.0 46669.0 51658.0 41455.0 50292.0 38144.0 49077.0 True False 39718.62113225987 28111.23684311518 54344.66951463428 60004.454709889826 40189.81491557815 48427.81709374953 45144.414691023834 42520.52699519008 40160.21396748063 47358.82916787619 0.8386740514945263 0.5935796415799743 1.1475087215943387 1.2670172756422629 0.8486234905241106 1.0225720936234304 0.9532417816115605 0.897837377787879 0.8479984550530564 1.0 15.53134579382335 -5.258104409644792 24.9999726272499 0.9979889149054767 0.7161268440370293 0.4111231779634045 0.13498751515778915 287.517896585376 2155298.826313696 0.036570987429588225 0.08889894356909818 5.519447291420199e-06 5.258104409644792 -0.2818620708684474 RLGDS(ph)SLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLGDSSLSR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 RLGDS(0.498)S(0.498)LS(0.004)R 87.667 0.0049113 20476000.0 18587.0 13133.0 15057.0 20354.0 26132.0 24868.0 26971.0 28392.0 28253.0 18619.0 True False 21733.411990016226 14436.757447026685 15416.015983990492 19213.631368558337 21011.6221901316 23563.87830238797 24416.111626869748 27646.740083810633 28666.146675575295 21994.47731207709 0.9881304148147446 0.6563810197526044 0.7009039480799851 0.8735661728141272 0.9553135494879067 1.0713543208162135 1.110101926062273 1.256985546486704 1.303333844620841 1.0 14.42485369626762 -6.6596268621741705 1.207777196597657 1.1966010132299458 0.7727537469718101 0.679027494617354 0.11333976934819491 0.24834033397595923 0.7652469149497808 0.05440220168426894 0.05403148571902904 2.189642116198429e-07 6.6596268621741705 -0.42384726625813574 RLGDS(ph)SLSR ddPTM_PC-9_Lapatinib_30min_R1 2 RLGDSSLSR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 RLGDS(0.604)S(0.324)LS(0.072)R;RLGDS(0.847)S(0.153)LSR 87.667 0.011309 42101000.0 139709.0 98129.0 106687.0 104730.0 82874.0 84421.0 78475.0 65268.0 108527.0 68281.0 True False 137716.72404050754 97901.78832952784 97915.60668372951 112432.19356903824 77999.51425655294 80810.51062496277 82538.05151887596 68300.58955254841 96303.54642002558 80083.2798712867 1.7196688779711797 1.2224997338630463 1.2226722836664994 1.4039409193747323 0.9739800165767077 1.0090809311861966 1.0306527361458557 0.8528695335945788 1.2025424854577484 1.0 16.289213441599735 -1.522878745434756 0.4397646185736951 0.9967691249270698 14.812558559527162 0.6813814486350358 0.13550364227740638 49.74629052376862 0.6127686025395199 0.08737872505105501 613.0151741644735 0.029999999989333146 1.522878745434756 13.815789434600092 RLGDSS(ph)LSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLGDSSLSR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 RLGDS(0.302)S(0.676)LS(0.022)R 95.618 0.0024609000000000002 12963000.0 11638.0 14366.0 17494.0 20660.0 32656.0 29552.0 15212.0 28166.0 29868.0 17644.0 True False 13608.083539022367 15792.161538413564 17911.123306364454 19502.487180623724 26257.291223057462 28002.241096677255 13771.009234657326 27426.672344343817 30304.762995295456 20842.717530172853 0.6528939193904392 0.7576824622582022 0.8593468332733247 0.9356979075492938 1.2597825204437103 1.343502403472098 0.6607108317196063 1.3158875422381815 1.45397369375778 1.0 14.347255771931016 -5.823479483971494 1.7083711719645547 1.1696118440875203 0.7128707177458827 0.442678251705805 0.21166196231015674 0.3633004331226052 2.162472092500467 0.07036840089991314 0.1395908706075481 1.501483334003464e-06 5.823479483971494 -0.45674112634163755 RLGDSSLS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 RLGDSSLSR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 RLGDS(0.03)S(0.224)LS(0.746)R 101.56 0.0015865 22449000.0 18065.0 18249.0 32583.0 42695.0 25875.0 28302.0 32140.0 22222.0 16786.0 18979.0 True False 23809.294224657388 24147.63237135474 32150.928130646018 32852.327381174466 22282.702885011156 26532.271465935577 35000.397736569896 18788.100510759432 17673.273690701797 18314.550986757997 1.3000206361527653 1.3184943703405148 1.7554854691164508 1.7937828453958682 1.2166666221368059 1.4486989872216498 1.911070479526159 1.0258564637671885 0.9649853661976281 1.0 14.160702710837892 -7.86736035637394 9.022388111518516 0.9882772428053442 1.5290268987158144 0.5645692441024301 0.21659998231820005 0.21327010019494777 16.59262324758467 0.12382536316402117 0.059363433678983765 1.3571868518160974e-08 7.86736035637394 0.5407496559104702 RLGDSSLS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 RLGDSSLSR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 RLGDS(0.099)S(0.099)LS(0.801)R 89.9 0.0041206 18322000.0 39429.0 19615.0 25791.0 23723.0 18791.0 27366.0 14380.0 14166.0 22302.0 14819.0 True False 38866.73522960697 19569.58267264201 23670.56353613903 25467.66855760809 17685.750324527435 26195.61997326179 15124.526038119624 14824.204075525538 19790.11390952862 17380.444404923706 2.2362336844848696 1.1259541020192867 1.361907842208764 1.465305947550648 1.0175660594453637 1.507189307877584 0.8702036429997726 0.852924340146676 1.1386425714133224 1.0 14.085177350803187 -3.0094763822199533 1.4923567241457103 1.1405762911062367 199.99999999939425 0.6678639551164023 0.22640605404110659 161.97288035321955 2.5823247583792814 0.066126456039009 108368.68152979069 0.0009784161615149169 3.0094763822199533 198.859423708288 RLGS(ph)VEAPK ddPTM_PC-9_AZD4547_30min_R2 2 RLGSVEAPK 9 1 P46087-2;P46087;P46087-4;P46087-3;F5H359;F5GWB7;F5H709;F5H5X6 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 RLGS(1)VEAPK;RLGS(1)VEAPK 72.29 0.014983000000000002 33132000.0 57843.0 78795.0 80337.0 99711.0 76290.0 75774.0 58988.0 75600.0 62312.0 65561.0 True False 76235.87079085837 104263.9428297933 79271.67888873671 76724.16946959337 65698.45036125621 71035.83980142043 64237.81772510222 63917.757115174834 65605.68510753065 63265.72934521525 1.205010541724262 1.6480319425524605 1.2529955745263526 1.2127287595301541 1.0384524297944404 1.1228170533497979 1.015365165152569 1.0103061764514203 1.0369861501089668 1.0 15.949136591801333 -5.855208181270719 1.6421956461465863 1.0377814687563753 1.4262462829291893 0.6519128897893277 0.11061587035560119 0.20893702141177323 1.148207007725058 0.03401081854051546 0.06640956188360754 1.3956991651777559e-06 5.855208181270719 0.388464814172814 RLGS(ph)VEAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RLGSVEAPK 9 1 P46087-2;P46087;P46087-4;P46087-3;F5H359;F5GWB7;F5H709;F5H5X6 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 RLGS(1)VEAPK;RLGS(1)VEAPK 75.89 0.011604000000000001 15310800.0 97753.0 94996.0 101331.0 119798.0 132049.0 125419.0 131964.0 132118.0 125718.0 99376.0 True False 114300.65219024377 104426.5750733076 103747.11533995766 113086.1064503562 106174.9463716779 118841.80685246886 119463.41458337638 128650.04249059211 127556.38791491109 117392.08214001692 0.9736657712052 0.8895538197265724 0.8837658677543131 0.9633197093776319 0.904447254330492 1.0123494249869665 1.0176445668702674 1.0959005083251483 1.0865842532954728 1.0 16.840975579285505 -7.025121011268078 1.6825680236746918 1.06415561467642 0.9191657287008607 0.7028184272455285 0.038950375615399095 0.18967305913607757 1.079658691949477 0.018376595859807845 0.013613408541233033 9.437978609958462e-08 7.025121011268078 -0.14498988597555929 RLGS(ph)VEAPK ddPTM_PC-9_Lapatinib_30min_R1 3 RLGSVEAPK 9 1 P46087-2;P46087;P46087-4;P46087-3;F5H359;F5GWB7;F5H709;F5H5X6 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 RLGS(1)VEAPK;RLGS(1)VEAPK;RLGS(1)VEAPK 78.653 0.017143000000000002 41322000.0 162123.0 157580.0 161180.0 155311.0 200247.0 203649.0 207651.0 215991.0 217534.0 171581.0 True False 159811.096290283 157215.13319168665 147928.40257279234 166733.08904230813 188468.86516074958 194939.40699900562 218402.15273585398 226026.73037391237 193033.03018542708 201238.5472326889 0.7941375968367332 0.781237667204491 0.7350897957027344 0.8285345493451478 0.9365445524848978 0.9686981429735742 1.085289849977495 1.1231781061933492 0.959224924051087 1.0 17.61854715420685 -6.464727757494504 1.4486686360484289 1.047930604547073 0.769351652933833 0.8551132753862658 0.04766755916986121 0.13943951814753994 0.5963551263767508 0.019540626428352463 0.02274343292113114 3.429827218475144e-07 6.464727757494504 -0.2785789516132401 RLHPPS(ph)PVPQGVCPAHR ddPTM_PC-9_AZD4547_30min_R2 1 RLHPPSPVPQGVCPAHR 17 1 Q96F44-2;Q96F44-3;Q96F44 Q96F44-2 TRIM11 E3 ubiquitin-protein ligase TRIM11 1 RLHPPS(1)PVPQGVCPAHR 84.759 0.0012288 7028500.0 10264.0 10270.0 12716.0 13657.0 13386.0 12705.0 13045.0 13703.0 10097.0 14682.0 True False 13527.738495537404 13589.57665920396 12547.3775315132 10508.589648546655 11527.584959179101 11910.554341555777 14205.979728486453 11585.516213614286 10630.70680656595 14167.987648853004 0.9548101558821281 0.9591747957448374 0.885614657670103 0.7417136370384538 0.813636011329551 0.840666623712085 1.0026815438137768 0.8177248950772633 0.750332868015069 1.0 13.790347239062312 -5.386549566236026 4.234610242695793 0.846913391248738 0.9562688743051785 0.19044590788587135 0.08392352443510906 0.35178936931955346 10.30675546061303 0.022779709535278095 0.05042997514840313 4.106297718289405e-06 5.386549566236026 0.1093554830564405 RLHPPS(ph)PVPQGVCPAHR ddPTM_PC-9_Lapatinib_30min_R1 2 RLHPPSPVPQGVCPAHR 17 1 Q96F44-2;Q96F44-3;Q96F44 Q96F44-2 TRIM11 E3 ubiquitin-protein ligase TRIM11 1 RLHPPS(1)PVPQGVCPAHR;RLHPPS(1)PVPQGVCPAHR 58.723 0.015128 13975500.0 34292.0 31126.0 37358.0 31562.0 33169.0 33481.0 28167.0 32706.0 34193.0 28174.0 True False 33802.98979161738 31053.929659375746 34286.56944605028 33883.17476774552 31218.064632763035 32049.09567802301 29625.349437810513 34225.640159123126 30341.824271747453 33043.838360504786 1.022974069260064 0.9397797350471412 1.037608557213827 1.025400693408667 0.9447469235316203 0.9698962731983726 0.8965468573777986 1.0357646646774206 0.9182294121137308 1.0 15.012093658983293 -6.2664962045366215 24.968455723203427 0.9598880090592697 1.003905532825674 0.20244318176763043 0.044177890913166054 701.4417876935627 3463418.01648982 0.013085144282076898 0.015282851683860435 5.413819792034442e-07 6.2664962045366215 0.04401752376640433 RLHT(ph)KGS(ph)TEAET(ph)RK ddPTM_PC-9_Lapatinib_30min_R1 1 RLHTKGSTEAETRK 14 3 E7EUF1;Q13822-3 E7EUF1 ENPP2 3 RLHT(0.992)KGS(0.504)T(0.504)EAET(1)RK 85.006 0.020163 0.0 9575.3 10796.0 9886.9 8117.4 11527.0 9404.7 10222.0 9790.1 9060.2 9353.8 True False 9438.754466105034 10771.00252530426 9074.037246537671 8714.380674852595 10849.004522953954 9002.482904426484 10751.245143369875 10244.983786517196 8039.744867864367 10970.591866844949 0.8603687550013236 0.981806875694293 0.8271237647588552 0.7943400666639492 0.9889169750031033 0.8206013872080654 0.980005935309837 0.9338588027761139 0.7328451341045586 1.0 13.421353741236592 -6.2544618217677055 24.980948954297073 0.9051575412645769 0.871417797864056 0.051381460237309606 0.08915652491131307 2526.0740967593606 9043806.72041523 0.026252465354758128 0.033122088070322825 5.565935614843181e-07 6.2544618217677055 -0.03373974340052088 RLKEDILENEDEQNS(ph)PPK ddPTM_PC-9_AZD4547_30min_R2 1 RLKEDILENEDEQNSPPK 18 2 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 RLKEDILENEDEQNS(1)PPK 66.82600000000001 0.0043411000000000005 8988900.0 66104.0 50551.0 42842.0 51831.0 50302.0 50984.0 54999.0 45041.0 43581.0 46439.0 True False 87123.69695138418 66890.62217131643 42273.88708753447 39882.16373096739 43318.43557572293 47795.9624202975 59893.804452819175 38080.94838921411 45884.602687625105 44813.18474493151 1.9441532095359078 1.4926549530466462 0.9433359250887823 0.8899649502254616 0.9666448796773445 1.0665602699817793 1.336521936428393 0.8497710797829686 1.0239085427378551 1.0 15.45163563789553 -4.987417191602043 2.6148170328072213 1.0122886098079433 1.9673515752756288 0.8447450393844212 0.12842464109719925 0.1258828674418143 1.5070164167808189 0.03621354147584681 0.21745561436643437 1.0293967870506058e-05 4.987417191602043 0.9550629654676854 RLKEDILENEDEQNS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 2 RLKEDILENEDEQNSPPK 18 2 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 RLKEDILENEDEQNS(1)PPK;RLKEDILENEDEQNS(1)PPK 65.107 0.0048842 20565000.0 176575.0 177232.0 138716.0 152181.0 143586.0 163155.0 129571.0 137047.0 141200.0 127175.0 True False 174057.0081201109 176821.63019310188 127311.30593924457 163372.8984009342 135140.55378093757 156177.24098288117 136279.552384228 143414.70393467083 125296.56909808262 149157.02929996402 1.1669380178527924 1.185472994621679 0.8535387607057636 1.0953080734289846 0.906028729689712 1.0470659124539083 0.9136649678786603 0.9615014767172319 0.8400312723184066 1.0 17.186472443375344 -5.245554127864348 24.800595175873887 0.9562495274217219 1.176205561648896 0.5799155411361093 0.07621687573506729 485.0111427711367 757212.5460610158 0.01820947294010891 0.04782696603721679 5.681275791267758e-06 5.245554127864348 0.21995603422717414 RLLAEK ddPTM_PC-9_AZD4547_30min_R2 1 RLLAEK 6 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;B5MCA1;A0A3B3ISJ8;Q96G28;Q96G28-2;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA;CFAP36 Prelamin-A/C;Lamin-A/C;Cilia- and flagella-associated protein 36 0 84.244 0.026872000000000004 2640500.0 36909.0 33427.0 43275.0 49322.0 52013.0 39747.0 35603.0 31328.0 41304.0 41288.0 False True 48645.2942451082 44231.62404938767 42701.14522461731 37951.57491730379 44791.89275973275 37261.61380667591 38771.59802784996 26486.977445822686 43487.24511621278 39842.51968708912 1.2209392033223139 1.1101613150164502 1.0717481113137157 0.9525395285078296 1.1242233952951388 0.9352223227676649 0.97312113622206 0.6647917263728109 1.0914782864574883 1.0 15.282021267545815 -4.683472212002127 0.46122047616596723 0.9134712188605342 1.442856643347465 0.3554534380939399 0.11560645518438323 5.649377871850401 0.8724048005295757 0.07940203412532752 1.6729088833500405 2.0726586728084928e-05 4.683472212002127 0.5293854244869308 RLLAEK ddPTM_PC-9_Lapatinib_30min_R1 1 RLLAEK 6 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;B5MCA1;A0A3B3ISJ8;Q96G28;Q96G28-2;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA;CFAP36 Prelamin-A/C;Lamin-A/C;Cilia- and flagella-associated protein 36 0 69.176 0.046189999999999995 5782900.0 65511.0 63376.0 58184.0 55751.0 61315.0 56778.0 56748.0 71052.0 74173.0 47545.0 False True 64576.80112675397 63229.2567658098 53400.336116735045 59851.11451988401 57708.5722499281 54349.737295982515 59686.13376990347 74353.33530807863 65818.85566368335 55763.08990026972 1.1580563638465382 1.133890838525861 0.9576287148405805 1.073310582805321 1.0348883527282617 0.9746543348509752 1.0703519815105291 1.3333790405276482 1.180330139190601 1.0 15.767022884448183 -7.555881190986141 24.977740108716766 1.194486041563419 1.0517504847551291 0.21995321587772287 0.0953500634348344 225.6695824144438 170794.4736355721 0.04394756973754001 0.02537331728088949 2.7804738120065973e-08 7.555881190986141 -0.14273555680828998 RLLEDGEDFNLGDALDS(ph)SNSMQTIQK ddPTM_PC-9_AZD4547_30min_R2 2 RLLEDGEDFNLGDALDSSNSMQTIQK 26 1 P05783 P05783 KRT18 Keratin, type I cytoskeletal 18 1 RLLEDGEDFNLGDALDS(0.333)S(0.333)NS(0.333)MQT(0.001)IQK;RLLEDGEDFNLGDALDS(0.452)S(0.452)NS(0.089)MQT(0.008)IQK 125.75 3.8818000000000004e-11 9281000.0 72212.0 65746.0 89811.0 124083.0 102624.0 92337.0 74850.0 95796.0 84776.0 87751.0 True False 95173.91389709174 86997.10876689613 88620.04745853513 95477.58141323968 88376.42901918407 86563.15279309195 81511.50499633668 80992.9293730859 89257.08628636585 84678.86419932556 1.1239394245187546 1.0273768972870687 1.0465427033826578 1.1275255320913968 1.0436657347122043 1.0222521713249597 0.9625956343068888 0.9564716076308802 1.0540657002231824 1.0 16.369714298103858 -6.77635857778324 2.5784541672488293 0.9905020605612688 1.0753108567216176 0.5016849251600533 0.03858511741651384 0.23650836926760516 3.2230141242661228 0.014646956281610236 0.013446403773303334 1.6735605203819638e-07 6.77635857778324 0.08480879616034886 RLLEDGEDFNLGDALDS(ph)SNSMQTIQK ddPTM_PC-9_Lapatinib_30min_R1 1 RLLEDGEDFNLGDALDSSNSMQTIQK 26 1 P05783 P05783 KRT18 Keratin, type I cytoskeletal 18 1 RLLEDGEDFNLGDALDS(0.311)S(0.311)NS(0.311)MQT(0.067)IQK 73.036 5.0303e-05 2918200.0 29844.0 18620.0 26753.0 17595.0 20779.0 22171.0 19968.0 18983.0 24551.0 20256.0 True False 29418.41908728068 18576.88653400939 24553.47160956643 18888.994995199362 19556.82007308581 21222.798013125288 21001.845335825634 19865.01948084859 21785.807846508684 23757.22261057659 1.238293699962375 0.7819468983608824 1.0335160810689779 0.7950843120352832 0.8231947140310593 0.8933198278689787 0.8840193856025798 0.8361675860209681 0.9170182981241989 1.0 14.536078564166335 -4.751689150007882 24.99684343988745 0.8799407260532592 1.2382944187474747 0.6458310655239661 0.07842808403233754 232.02216252614835 594798.2193110867 0.018182519244655974 0.23413209840327817 1.7713763824836796e-05 4.751689150007882 0.35835369269421546 RLLEDGEDFNLGDALDSSNS(ph)MQTIQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RLLEDGEDFNLGDALDSSNSMQTIQK 26 1 P05783 P05783 KRT18 Keratin, type I cytoskeletal 18 1 RLLEDGEDFNLGDALDS(0.253)S(0.253)NS(0.37)MQT(0.124)IQK;RLLEDGEDFNLGDALDS(0.024)S(0.024)NS(0.715)MQT(0.237)IQK;RLLEDGEDFNLGDALDS(0.036)S(0.042)NS(0.7)MQT(0.222)IQK 110.75 1.2841e-10 12899800.0 70537.0 72885.0 75596.0 84862.0 95464.0 81909.0 73514.0 71626.0 74725.0 57025.0 True False 82477.52093074608 80120.54111981559 77398.49533942644 80107.45726631621 76758.51449405814 77613.54784744636 66550.22172473051 69745.89339402017 75817.71175918881 67363.18109034836 1.224370933731977 1.1893817931839783 1.1489732831295274 1.1891875646263657 1.1394728285041742 1.1521657171051658 0.9879316957355756 1.0353711369490715 1.1255067016134694 1.0 16.03967264792566 -7.130402735844945 5.0443199590466214 1.0406945293703873 1.1750479810807348 0.7314876223577772 0.0407278665714574 0.12775162565764867 4.700914910884099 0.016152375345922492 0.012445741755077426 7.406231180864345e-08 7.130402735844945 0.13435345171034752 RLLGPAPEDDGGHNDHSQPQASQDQDSHTLS(ph)PQV ddPTM_PC-9_AZD4547_30min_R2 2 RLLGPAPEDDGGHNDHSQPQASQDQDSHTLSPQV 34 1 Q92610 Q92610 ZNF592 Zinc finger protein 592 1 RLLGPAPEDDGGHNDHS(0.181)QPQAS(0.193)QDQDS(0.17)HT(0.17)LS(0.286)PQV;RLLGPAPEDDGGHNDHS(0.006)QPQAS(0.128)QDQDS(0.095)HT(0.095)LS(0.676)PQV 50.099 0.0023122 13701100.0 12014.0 6020.7 17246.1 27144.9 25902.1 18324.7 11923.9 22608.7 22925.4 17354.3 True False 15834.202093276164 7966.773533794487 17017.40544559843 20887.062689524344 22306.040517791203 17178.853612176856 12985.104000344927 19115.044911241424 24137.189840868297 16746.73123923781 0.9455100142872312 0.47572110759908964 1.016162808281441 1.2472322145222992 1.3319638441159107 1.025803386151357 0.7753814051736053 1.141419459007894 1.4413075301712936 1.0 14.03159190585731 -5.458381540294075 6.604927651506172 1.1320574044787852 0.7141691715729279 0.40580900271976506 0.20383574741440486 0.23628370200045362 19.736577893417838 0.05547282240767861 0.11563738907243537 3.4803142499154023e-06 5.458381540294075 -0.4178882329058573 RLLGPAPEDDGGHNDHSQPQASQDQDSHTLS(ph)PQV ddPTM_PC-9_Lapatinib_30min_R1 1 RLLGPAPEDDGGHNDHSQPQASQDQDSHTLSPQV 34 1 Q92610 Q92610 ZNF592 Zinc finger protein 592 1 RLLGPAPEDDGGHNDHS(0.001)QPQAS(0.026)QDQDS(0.051)HT(0.051)LS(0.872)PQV 46.886 0.0038260999999999994 6059400.0 6314.9 4027.1 6235.3 4148.7 6587.2 8137.9 3605.5 5751.9 6268.6 3719.1 True False 6224.848367989166 4017.7754973742863 5722.657702954045 4453.809237657495 6199.753846933482 7789.86098737145 3792.1751481530096 6019.1542723433095 5562.564256715589 4361.941479610751 1.427082045251248 0.9210979826654673 1.3119519667340243 1.0210612082890533 1.4213289829570874 1.785870127736468 0.8693778139571496 1.3799254988813934 1.2752496297157976 1.0 12.090754699381305 -3.5505357531766415 15.661170346684813 1.2485958152525052 45.06904329773511 0.0 0.27147056590361823 0.0 1.3425963210461124e-17 0.06046516291172268 0.0 0.0002814908269026594 3.5505357531766415 43.8204474824826 RLLS(ph)DIFIPALR ddPTM_PC-9_AZD4547_30min_R2 1 RLLSDIFIPALR 12 1 Q8TE73 Q8TE73 DNAH5 Dynein heavy chain 5, axonemal 1 RLLS(1)DIFIPALR 51.727 0.045821 22128000.0 77511.0 129900.0 45723.0 77015.0 77958.0 74857.0 75209.0 52916.0 65785.0 68000.0 True False 102157.8856710446 171887.63466704902 45116.68314512251 59260.381619888685 67134.87735303181 70176.17995638243 81902.45530086127 44739.048088711475 69262.26079726065 65619.34069758913 1.556825847151462 2.6194660421719873 0.6875516069727916 0.9030932190098327 1.0230958836119237 1.069443539211919 1.2481450503794895 0.6817966717296688 1.0555159509520242 1.0 16.00183347817419 -5.26951024580446 24.9999740157941 0.9618392723863021 2.0881459638777433 0.711127839602077 0.28796612438785013 258.479464016758 800656.652672976 0.07051789877946546 0.15097952774031717 5.376377491107002e-06 5.26951024580446 1.1263066914914412 RLLS(ph)VSK ddPTM_PC-9_AZD4547_30min_R2 2 RLLSVSK 7 1 Q6ISB3-2;Q6ISB3 Q6ISB3-2 GRHL2 Grainyhead-like protein 2 homolog 1 RLLS(1)VSK;RLLS(0.986)VS(0.014)K 108.57 0.0044653 12609200.0 72420.0 72107.0 89407.0 119440.0 86716.0 71867.0 69909.0 85475.0 69470.0 69282.0 True False 95448.05357042266 95414.1776207614 88221.40476250408 91904.95332960474 74676.98022711604 67373.1451290505 76130.76556832204 72266.80277010017 73142.0423741841 66856.45826779961 1.4276564455164051 1.4271497487732787 1.3195644377260496 1.3746608137911094 1.1169748168230902 1.0077283014182603 1.1387196920209766 1.0809247848671393 1.0940161095762357 1.0 16.028779309514917 -6.286771400209192 3.6506225720543055 1.0725475088721552 1.389457838150176 0.9145030615691743 0.047260060840454365 0.06450424997397293 1.865089595237373 0.015118940345445453 0.018257534077262244 5.166882671526079e-07 6.286771400209192 0.3169103292780209 RLNECIS(ph)PVANEMNHLPAHSHDLQR ddPTM_PC-9_AZD4547_30min_R2 2 RLNECISPVANEMNHLPAHSHDLQR 25 1 P23497;P23497-5;P23497-2;P23497-3;P23497-4 P23497 SP100 Nuclear autoantigen Sp-100 1 RLNECIS(0.998)PVANEMNHLPAHS(0.002)HDLQR;RLNECIS(0.999)PVANEMNHLPAHS(0.001)HDLQR 49.152 0.0069342 58994000.0 39406.0 31861.0 52959.0 140139.0 113648.0 56736.0 44068.0 58163.0 47503.0 69401.0 True False 51936.28830428168 42159.44517418672 52256.72905720413 107832.11867596692 97869.93690727513 53188.28895100422 47989.9666289721 49175.24480277659 50013.911600703424 66971.29211402044 0.7755007655497932 0.6295151824517455 0.7802855135038403 1.6101245066674212 1.4613714894532557 0.7941953525467258 0.716575193849745 0.7342734961579419 0.7467962767621892 1.0 16.031255182577965 -6.955632580241521 24.999713030095506 0.7741394015017478 1.052294388676482 0.1540841829120012 0.29402855221925595 274.2913324427165 154554.0737232888 0.11828995381169892 0.10432187366948352 1.1075604007247668e-07 6.955632580241521 0.2781549871747342 RLNECIS(ph)PVANEMNHLPAHSHDLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RLNECISPVANEMNHLPAHSHDLQR 25 1 P23497;P23497-5;P23497-2;P23497-3;P23497-4 P23497 SP100 Nuclear autoantigen Sp-100 1 RLNECIS(1)PVANEMNHLPAHSHDLQR;RLNECIS(0.996)PVANEMNHLPAHS(0.004)HDLQR 75.73 3.7456e-05 59613000.0 30393.0 4152.2 20360.4 61568.0 54777.0 68516.0 43592.0 66525.0 51396.0 37937.0 True False 35537.93461088734 4564.402975066182 20845.869153246993 58118.544566149154 44043.84006998468 64922.90034447545 39462.65018125047 64778.789239063895 52147.569268320796 44814.67779087322 0.792997659756127 0.10185062573395877 0.465157180210551 1.296864050598738 0.9827994362809963 1.4486972470813433 0.8805742253777239 1.445481534896955 1.163627004341443 1.0 15.451683703528586 -5.752799350046481 21.325592503651837 1.1838201893153444 0.418184372193839 0.6595489996239665 0.2367971761163466 16.195678030611344 39971.36941424417 0.06013323966016657 0.1015332479477541 1.7668539426783093e-06 5.752799350046481 -0.7656358171215054 RLNHS(ph)PPQSSSR ddPTM_PC-9_AZD4547_30min_R2 2 RLNHSPPQSSSR 12 1 A0A087X0H9;Q5T8P6-3;Q5T8P6-2;Q5T8P6 A0A087X0H9 RBM26 RNA-binding protein 26 1 RLNHS(0.984)PPQS(0.003)S(0.011)S(0.002)R;RLNHS(0.987)PPQS(0.005)S(0.007)S(0.001)R 125.47 0.00013391 111382000.0 88567.0 76957.0 177056.0 292250.0 210579.0 169335.0 144848.0 206640.0 131570.0 194407.0 True False 116729.46369195869 101831.84527384223 174708.12175366457 224876.27771749007 181343.7407081262 158746.45568101917 157739.19139224236 174708.5361148111 138524.5215945213 187600.87010288527 0.6222224002902608 0.5428111565687034 0.9312756473775949 1.1986952810728542 0.9666465864932956 0.8461925341495401 0.8408233464254937 0.9312778561154665 0.7384002084774489 1.0 17.517306993602503 -5.2656970814296296 24.591271387232315 0.9336989408332681 0.5825167579483557 0.5939954934015114 0.11545306163865521 187.11306508395953 1080720.4179438904 0.032368081958736764 0.0714477301194898 5.423790656103634e-06 5.2656970814296296 -0.35118218288491243 RLNHS(ph)PPQSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLNHSPPQSSSR 12 1 A0A087X0H9;Q5T8P6-3;Q5T8P6-2;Q5T8P6 A0A087X0H9 RBM26 RNA-binding protein 26 1 RLNHS(0.882)PPQS(0.036)S(0.022)S(0.061)R 75.998 0.0087715 35575000.0 20132.0 22798.0 38182.0 31183.0 44706.0 38016.0 32039.0 32490.0 37385.0 25983.0 True False 23539.94997487528 25061.23477326692 39092.40368604136 29435.91760665005 35946.180224706244 36022.37403665682 29004.033977727173 31637.171926000545 37931.68489952865 30693.512218685177 0.766935690094956 0.8164994150786851 1.2736373539631356 0.959027347438279 1.171132842947293 1.1736152506759268 0.9449565032205892 1.0307445984217114 1.2358209327519423 1.0 14.905646120517092 -5.140647166692412 6.790146165255984 1.0940840839902088 0.7806518999169818 0.5608832169481848 0.10882482835833335 0.1654304125133742 8.423806040189909 0.026812557424704692 0.0726696957901648 7.233572411377412e-06 5.140647166692412 -0.31343218407322704 RLNHS(ph)PPQSSSR ddPTM_PC-9_Lapatinib_30min_R1 2 RLNHSPPQSSSR 12 1 A0A087X0H9;Q5T8P6-3;Q5T8P6-2;Q5T8P6 A0A087X0H9 RBM26 RNA-binding protein 26 1 RLNHS(0.989)PPQS(0.002)S(0.005)S(0.004)R;RLNHS(0.984)PPQS(0.01)S(0.006)SR 105.19 0.00083454 45984700.0 37107.2 24784.3 41953.6 25098.2 35685.7 33368.7 23529.4 26957.4 39813.5 22849.4 True False 36578.04452337292 24726.913476092854 38504.33695357927 26944.005353140805 33586.73728678561 31941.59848723892 24747.637201761598 28209.939216827064 35329.28437525863 26798.888345088286 1.3649090235519774 0.9226842978591243 1.4367885883086031 1.0054150383472573 1.2532884519048122 1.1919001294355254 0.9234576032814196 1.052653335973072 1.3183115627903945 1.0 14.709885536490283 RLNHSPPQS(ph)SSR ddPTM_PC-9_Lapatinib_30min_R1 1 RLNHSPPQSSSR 12 1 A0A087X0H9;Q5T8P6-3;Q5T8P6-2;Q5T8P6 A0A087X0H9 RBM26 RNA-binding protein 26 1 RLNHS(0.122)PPQS(0.333)S(0.333)S(0.212)R 54.393 0.038986 7547500.0 2501.7 2166.5 3046.8 3229.4 3532.0 3056.0 2433.3 2378.7 2949.4 2682.3 True False 2466.025299244406 2161.483602359364 2796.3038649881146 3466.900848962592 3324.2547041791736 2925.3020038839413 2559.284367771659 2489.2230858712815 2617.207513441114 3145.9319810599113 0.783877500877678 0.6870725798817583 0.8888634216579591 1.1020266394299287 1.0566835914421717 0.9298681667295182 0.8135218381007074 0.7912514004936068 0.8319339163077956 1.0 11.619271762901892 -5.366206448617904 5.386780692584962 0.9283059806633575 0.7370894838605623 0.3777086780797825 0.09910117476294285 0.2543517742776261 10.61422956977447 0.030181697763673906 0.06466380744059969 4.303220016257742e-06 5.366206448617904 -0.19121649680279518 RLNHSPPQSSS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 RLNHSPPQSSSR 12 1 A0A087X0H9;Q5T8P6-3;Q5T8P6-2;Q5T8P6 A0A087X0H9 RBM26 RNA-binding protein 26 1 RLNHS(0.173)PPQS(0.003)S(0.047)S(0.778)R 89.46600000000001 0.0034273000000000003 42613000.0 20428.0 12892.0 17401.0 11458.0 20367.0 16965.0 12441.0 15740.0 18503.0 12413.0 True False 20136.692973963596 12862.149366082116 15970.356949802464 12300.659542767507 19169.05310306264 16239.446497346567 13085.134105719484 16471.33786169504 16418.997294772136 14558.57051071717 1.3831504239471957 0.8834761185250812 1.0969728750529468 0.844908470492517 1.3166851160937472 1.1154561146914825 0.898792508240213 1.1313842832007306 1.127789111072782 1.0 13.8295810854745 -7.193279933111074 0.007924146326415847 9.94161243665202e-07 2.1412144615530195 0.025863793153835246 0.1673555436048517 20067.184651422667 89.04411388492414 11861.299435766707 12189.667399018092 6.40796405424246e-08 7.193279933111074 2.141213467391776 RLNS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLNSSPR 7 1 Q9UBS0 Q9UBS0 RPS6KB2 Ribosomal protein S6 kinase beta-2 1 RLNS(0.809)S(0.191)PR 66.29899999999999 0.025038 525600.0 0.0 0.0 447.75 0.0 1112.3 937.88 0.0 538.91 787.69 996.32 True False 0.0 0.0 458.4260581013312 0.0 894.3527997123603 888.6959217566211 0.0 524.7641835223436 799.2084760869254 1176.9449291352191 0.0 0.0 0.38950510491443957 0.0 0.7598934984744797 0.7550870901067614 0.0 0.44586978585983905 0.6790534172861918 1.0 10.200831100941345 -8.452627917204723 0.2157763628059992 1.1807596920165955 1.6242389207600177e-15 0.4766455983519583 0.2643854530761745 3.4494126863744254 0.6246678375709788 1.5324895193221626 1.0234728818896697 3.526728949572855e-09 8.452627917204723 -1.180759692016594 RLPDAHSDYAR ddPTM_PC-9_AZD4547_30min_R2 2 RLPDAHSDYAR 11 1 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 0 ; 67.214 0.015976 21586000.0 4400.5 3768.16 5850.5 11835.0 7061.99 8118.3 4676.9 8275.9 4332.3 8016.9 False True 5799.767463913912 4986.144029614999 5772.918547351208 9106.62359892727 6081.554587320572 7610.661417634965 5093.135039644175 6997.049816262894 4561.296533434256 7736.2307711544445 0.7496890456705492 0.6445185229228805 0.7462185033151151 1.1771396004476127 0.786113388705576 0.9837686649695506 0.658348385706719 0.9044520546559076 0.589601922223113 1.0 12.917415115598141 -14.522868375526793 0.015524423111740786 1.907280000159461 1.8628951975547547e-07 0.04676244399004592 0.17336163821017714 24414.035898216902 28.6383047018839 2220.974344134309 1388.009944880702 3.0000716325749824e-15 14.522868375526793 -1.9072798138699412 RLPDAHSDYAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RLPDAHSDYAR 11 1 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 0 ; 155.53 4.3017e-05 15082200.0 14865.2 13168.5 10373.8 14858.099999999999 18916.800000000003 17907.9 16871.9 16169.5 14051.2 12411.8 False True 17381.58475891695 14475.781652415364 10621.150734855584 14025.64882761014 15210.18883538503 16968.77819894377 15273.67149002202 15745.067758001405 14256.67221774126 14661.961088245256 1.185488397786846 0.9873018735550215 0.7244017816532565 0.956601149272913 1.0373911609668163 1.157333462884984 1.041720912918476 1.0738718827063656 0.9723577993377077 1.0 13.83979046140225 -6.286276600211209 5.076829571115431 1.056900822979346 0.9476505223526128 0.10699612523225921 0.11365680423164468 0.3738834945957089 27.89901889894605 0.03720864419503681 0.04395633211867822 5.172772754342741e-07 6.286276600211209 -0.10925030062673313 RLPDAHSDYAR ddPTM_PC-9_Lapatinib_30min_R1 1 RLPDAHSDYAR 11 1 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 0 56.551 0.031784 7686700.0 4140.0 2588.1 2267.7 4180.2 3839.5 3642.4 3515.0 0.0 2459.2 2002.5 False True 4080.9628408169833 2582.107413462389 2081.258459575142 4487.625852738414 3613.6681587474354 3486.6230428491094 3696.9895009729116 0.0 2182.2189994759547 2348.6294568364738 1.7375933138103041 1.099410299034741 0.886158714188371 1.910742386235374 1.5386284746743009 1.4845351754829283 1.5741050552745064 0.0 0.9291457165045233 1.0 11.197603402034066 -7.739692097379782 24.999980935291493 0.5984294103368516 1.4466538324415021 0.5017675141837794 0.3727795691071902 178.02452375258392 204651.6868639354 0.17464706516836762 0.10072127122281574 1.820991432973395e-08 7.739692097379782 0.8482244221046505 RLPENLYNDR ddPTM_PC-9_AZD4547_30min_R2 2 RLPENLYNDR 10 1 E5RHG9;B7Z2R2;P14927;P14927-2 E5RHG9 UQCRB Cytochrome b-c1 complex subunit 7 0 ; 150.04 0.0001006 14263300.0 18887.4 18899.6 27544.0 31335.0 27628.0 29703.0 20539.6 36610.0 29016.0 26898.0 False True 24893.200317674717 25008.52609817831 27178.748563070127 24111.199870924036 23792.329093993743 27845.666714461335 22367.584609522433 30952.765714107773 30549.726522661957 25956.309207114024 0.959042370740909 0.963485443890615 1.047096039201947 0.9289148036622908 0.9166298992721514 1.072789913707357 0.8617397963263589 1.1924948754125775 1.1769672752353013 1.0 14.66379763703361 -7.7725645023707886 24.999830740143175 1.1385483316678153 0.9683850293003794 0.4806678552931628 0.07509909169255495 171.19561402541382 384696.2442469315 0.038338682622400255 0.018687835811823917 1.6882450989935435e-08 7.7725645023707886 -0.17016330236743593 RLPENLYNDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RLPENLYNDR 10 1 E5RHG9;B7Z2R2;P14927;P14927-2 E5RHG9 UQCRB Cytochrome b-c1 complex subunit 7 0 ;; 138.76 7.5814e-05 13309000.0 52324.3 48095.7 60769.9 57500.8 65082.7 65382.0 65523.7 48890.8 55764.3 51105.7 False True 61181.7705379677 52870.32324259203 62218.88488712915 54279.21659610883 52330.2121350711 61953.25282156712 59316.82078549278 47607.46830408457 56579.74739180914 60370.75885750142 1.013433849363739 0.8757604549478439 1.0306129335559624 0.8990978020373901 0.8668138868121709 1.0262129215205162 0.9825422424373306 0.7885848911797977 0.9372045086489545 1.0 15.881562315420531 RLPENLYNDR ddPTM_PC-9_Lapatinib_30min_R1 2 RLPENLYNDR 10 1 E5RHG9;B7Z2R2;P14927;P14927-2 E5RHG9 UQCRB Cytochrome b-c1 complex subunit 7 0 ; 143.24 7.2204e-05 7592400.0 67412.0 31489.0 30159.0 20022.1 20560.7 16782.2 15911.6 14544.2 25156.0 11597.9 False True 66450.69251815314 31416.089155178375 27679.443437106627 21494.59202576761 19351.360049891486 16064.46442721896 16735.42479194327 15219.976628212511 22322.666375576257 13602.581561769659 4.8851530289599 2.309568151642182 2.0348669340017254 1.5801847559715145 1.4226240777911519 1.1809864439532916 1.2303124018001506 1.1189035374717822 1.6410610202341722 1.0 13.73159285844586 -2.4212132659489494 0.8284705662206022 1.2773867248255348 199.99999999993597 0.9588078487351418 0.22088285889800346 18.782720915048298 0.3045805837182475 0.07460790270298305 6724.578749714837 0.0037912876314821838 2.4212132659489494 198.72261327511043 up RLPS(ph)SPASPSPK ddPTM_PC-9_AZD4547_30min_R2 2 RLPSSPASPSPK 12 1 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 RLPS(0.621)S(0.379)PASPSPK;RLPS(0.73)S(0.267)PAS(0.002)PS(0.001)PK 72.615 0.011281999999999999 17943700.0 48194.0 87102.0 93424.0 125036.0 112089.0 93285.0 95495.0 127684.0 99980.0 100688.0 True False 63518.689502526344 115256.01812755455 92185.13671784279 96210.88198694288 96527.37714697637 87451.87420322961 103993.87000167211 107953.37168642825 105264.73868678467 97162.94376704187 0.6537336873491495 1.1862137318924042 0.9487684619649454 0.990201390126861 0.99345875500037 0.9000537737195824 1.0703038212902245 1.1110549711756113 1.0833835884920044 1.0 16.568118579833815 -7.31759382958705 10.285592408783895 1.0756019203264173 0.9607477257719852 0.17390986211885184 0.12566523068299257 1.2807239125678502 230.40474846354348 0.04974583586918646 0.0335328392215488 4.812892599291227e-08 7.31759382958705 -0.11485419455443213 RLPS(ph)SPASPSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLPSSPASPSPK 12 1 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 RLPS(0.5)S(0.5)PASPSPK 69.26100000000001 0.014928 5739700.0 42517.0 50462.0 58710.0 72096.0 96352.0 75645.0 74438.0 76810.0 71266.0 71302.0 True False 49714.28835097218 55471.533868260136 60109.869058914854 68056.6948583857 77472.5172686195 71678.04303458815 67386.69375554961 74793.81888692215 72308.13042797406 84228.48817367866 0.5902312795697057 0.6585839906550163 0.7136524750980766 0.8080009072233754 0.9197899540695971 0.8509952462495638 0.8000463408128451 0.8879871942221939 0.8584759384363531 1.0 16.362020650793937 -5.587603797576995 1.3790349743052617 0.876547565516616 0.6018819517037267 0.8110593378220079 0.05122182613769788 0.20314396897997675 0.7322952164773212 0.016393096139671264 0.051017704646269105 2.584617035148567e-06 5.587603797576995 -0.27466561381288923 RLPS(ph)SPASPSPK ddPTM_PC-9_Lapatinib_30min_R1 1 RLPSSPASPSPK 12 1 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 RLPS(0.592)S(0.407)PASPSPK 67.646 0.016683 13780000.0 70796.0 59027.0 50474.0 44902.0 42634.0 44459.0 38590.0 28742.0 47170.0 38351.0 True False 69786.43605760377 58890.32660810809 46324.2225552744 48204.242868680994 40126.35194166902 42557.59220899093 40588.00137767984 30077.458247829658 41857.21787787932 44979.919250504674 1.5515020306938583 1.3092581665194372 1.0298867433994925 1.0716836239793859 0.8920947971959465 0.9461464786536591 0.9023582535049669 0.6686863549114128 0.9305756563226751 1.0 15.456993450691835 -3.942911232342022 0.5731909624305623 0.8570683139097964 3.0636987656538976 0.8498027323505466 0.0896714866208265 3.127084602407155 0.38067384785784264 0.04396086475501866 5.668323335770989 0.00011404828728344893 3.942911232342022 2.2066304517441013 RLPS(ph)TEQDSGR ddPTM_PC-9_AZD4547_30min_R2 1 RLPSTEQDSGR 11 1 F5H212;P15822 F5H212 HIVEP1 Zinc finger protein 40 1 RLPS(0.796)T(0.201)EQDS(0.003)GR 61.167 0.027724000000000002 4540500.0 9604.2 12442.0 12191.0 13832.0 12267.0 10842.0 10009.0 14913.0 10019.0 10308.0 True False 12658.135820229963 16463.633183429 12029.339374542105 10643.2461022697 10563.938793833115 10164.048026064356 10899.781609997764 12608.538516648165 10548.583885806109 9947.120057511007 1.2725427809300327 1.655115559904941 1.2093288615189506 1.0699826724452826 1.062009780997501 1.021808118058206 1.0957726002077766 1.2675566841206 1.0604661273632603 1.0 13.280063174121384 -5.46598938999898 5.534879262633368 1.0936246225611008 1.4622999145973965 0.6528447988648218 0.10974426175495715 0.11855216372048749 7.737214859594771 0.028088969332607853 0.05852667196906427 3.419877973206592e-06 5.46598938999898 0.3686752920362957 RLPS(ph)TEQDSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLPSTEQDSGR 11 1 F5H212;P15822 F5H212 HIVEP1 Zinc finger protein 40 1 RLPS(0.839)T(0.159)EQDS(0.002)GR 58.071000000000005 0.033757 2057700.0 8568.5 11301.0 11432.0 13906.0 16752.0 20067.0 13506.0 11850.0 13153.0 12371.0 True False 10018.977814410826 12422.888594292886 11704.58223610143 13126.891903860289 13469.565855238206 19014.65119406544 12226.613905027725 11538.950056112843 13345.337741968711 14613.764371217883 0.6855850114939183 0.8500813533547884 0.8009286272025743 0.8982553413625567 0.9217040533215932 1.3011466936961977 0.8366505435867229 0.7895946426260333 0.9132032926610364 1.0 13.835040230528703 -5.803919181552309 1.9009433183216515 0.9588480379501972 0.7712247064624158 0.27220352924683966 0.13381854145735805 0.5297595054874696 3.9094522307040993 0.0449553039060665 0.08685156849501595 1.5706550624648554e-06 5.803919181552309 -0.18762333148778143 RLPS(ph)TEQDSGR ddPTM_PC-9_Lapatinib_30min_R1 1 RLPSTEQDSGR 11 1 F5H212;P15822 F5H212 HIVEP1 Zinc finger protein 40 1 RLPS(0.88)T(0.117)EQDS(0.004)GR 59.607 0.030764 3787400.0 7447.2 8922.8 8244.6 6637.8 11901.0 9099.3 10678.0 14210.0 13655.0 10040.0 True False 7341.001562350784 8902.139804815193 7566.760813076343 7125.96595505168 11201.006578266242 8710.144150504311 11230.854592144737 14870.248476155424 12117.030106475355 11775.400622540918 0.6234184124740827 0.7559946442734509 0.6425905203252077 0.6051569864562303 0.9512208490660481 0.7396898355909033 0.9537556259993575 1.2628231474086946 1.029012132570715 1.0 13.523488523576127 -7.122651983536986 1.1420115533281934 1.1126529568215746 0.679747762816211 0.6915846647519213 0.1139330787474105 0.2701169227739271 0.7054492660389118 0.07198367353606883 0.04624728268994368 7.539594977579052e-08 7.122651983536986 -0.43290519400536365 RLPSSPAS(ph)PSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RLPSSPASPSPK 12 1 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 RLPS(0.004)S(0.001)PAS(0.962)PS(0.033)PK;RLPS(0.241)S(0.241)PAS(0.516)PS(0.002)PK 166.03 9.8825e-05 16349700.0 43195.0 40751.0 44005.0 59741.0 79226.0 74016.0 79436.0 69366.0 66617.0 63610.0 True False 50507.06035986179 44796.489966023335 45054.24608989183 56393.90545293523 63702.23402859972 70134.4706622788 71911.2470131632 67545.21599935228 67591.14759801784 75141.98946351706 0.6721549525167148 0.5961578910254023 0.5995881452109618 0.750497902112581 0.8477581507145007 0.9333592464480926 0.9570048321395263 0.8989010868836103 0.8995123509583771 1.0 16.19733169290941 -6.179007480134265 1.701438017501441 0.9323373575855777 0.6175208658341071 0.9309820069269077 0.03738569965811695 0.0858977225923753 0.49260297322997043 0.013059074989982903 0.018655752559193405 6.62205098017581e-07 6.179007480134265 -0.31481649175147053 RLPSSPASPS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 RLPSSPASPSPK 12 1 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 RLPSSPAS(0.008)PS(0.992)PK;RLPSSPAS(0.024)PS(0.976)PK;RLPSSPAS(0.026)PS(0.974)PK;RLPSSPAS(0.004)PS(0.996)PK 108.66 0.00064446 186629000.0 275681.0 334057.0 329467.0 423273.0 442871.0 410322.0 404665.0 441541.0 438899.0 389748.0 True False 363341.8234789799 442034.39240931824 325098.0523100865 325693.94935266057 381386.00615991314 384664.5004750756 440679.4010600196 373310.9840527966 462098.30510993325 376103.0411500575 0.9660698896981634 1.1753012979040376 0.8643855984678915 0.8659699968305102 1.0140465894497988 1.0227636003655771 1.1716985848146797 0.9925763506492177 1.2286481483822018 1.0 18.520768446420902 -6.940569719581892 2.9242301769810024 1.097886047531691 0.9750660450713169 0.2262384511154163 0.10470279024637977 0.4184132095856338 7.271428022079569 0.04140271166329324 0.03475130959807809 1.1466484291311077e-07 6.940569719581892 -0.12282000246037406 RLPSSPASPS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLPSSPASPSPK 12 1 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 RLPS(0.001)S(0.001)PAS(0.002)PS(0.997)PK 100.73 0.0043228 7544100.0 16172.0 17471.0 24309.0 22822.0 21866.0 20844.0 31784.0 21270.0 21905.0 20423.0 True False 18909.60018844043 19205.405418183458 24888.618752395872 21543.357329922288 17581.51426639437 19750.903946235136 28773.189423767293 20711.68503742786 22225.31918481141 24125.52823162095 0.7838004626011013 0.7960615508103668 1.0316300026034146 0.8929693527574559 0.7287514742724082 0.8186723936824702 1.192644950507435 0.858496644657147 0.9212365827364989 1.0 14.558272910274086 RLPSSPASPS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 RLPSSPASPSPK 12 1 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 RLPSSPAS(0.009)PS(0.991)PK;RLPS(0.001)S(0.001)PAS(0.018)PS(0.98)PK;RLPSSPAS(0.004)PS(0.996)PK;RLPSSPAS(0.01)PS(0.989)PK 107.11 0.00072955 187129000.0 286875.0 263341.0 197514.0 216936.0 220216.0 203074.0 168438.0 182344.0 220910.0 169641.0 True False 282784.1098935682 262731.2500941234 181275.1613460888 232890.19711728167 207263.32784131408 194388.99840861507 177158.89546653652 190816.367919499 196028.78951457117 198963.2208175757 1.4212883603892086 1.3205015932819815 0.9110988483258189 1.1705188333818377 1.0417167906190488 0.9770097086779942 0.8904102714992184 0.9590534729755589 0.9852513882166442 1.0 17.602142241647563 -3.530334606589602 0.613300483013047 0.9635090525006382 3.4268322440246077 0.7472834175446246 0.08524526466768152 6.852733499557268 0.5981974769976177 0.038685208453571075 16.815874214199564 0.0002948936313284012 3.530334606589602 2.4633231915239695 RLPT(ph)PEQIFQNIK ddPTM_PC-9_AZD4547_30min_R2 1 RLPTPEQIFQNIK 13 1 Q9H9L7-2;Q9H9L7;H0YEQ5 Q9H9L7-2 AKIRIN1 Akirin-1 1 RLPT(1)PEQIFQNIK 116.58 0.00023073 1398400.0 7341.6 6605.6 9047.3 11479.0 11844.0 8523.8 9062.4 8918.4 9694.2 10542.0 True False 9676.076085233586 8740.73102045158 8927.326890599197 8832.693898782094 10199.665042321622 7990.805438532318 9868.93604380495 7540.266204444104 10206.615620898452 10172.927788735065 0.9511594190168473 0.859214888965454 0.8775572849818931 0.8682548507385385 1.0026282751771975 0.7854971159218186 0.9701175756632482 0.7412090561375827 1.0033115178700758 1.0 13.312447328991297 RLPT(ph)PEQIFQNIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLPTPEQIFQNIK 13 1 Q9H9L7-2;Q9H9L7;H0YEQ5 Q9H9L7-2 AKIRIN1 Akirin-1 1 RLPT(1)PEQIFQNIK 75.788 0.040858 0.0 7166.7 6176.0 7094.7 6295.6 8682.5 7764.2 8245.8 7305.5 7068.5 7148.8 True False 8379.880761222854 6789.112464237932 7263.8645547995775 5942.877942610586 6981.226452847761 7357.031683907058 7464.6981295777905 7113.738365817079 7171.8634402118 8444.820850130338 0.9923100690873173 0.8039380094289564 0.8601561458449964 0.703730493290318 0.8266873361487606 0.8711886035798508 0.883938009112719 0.8423788369302453 0.8492617626223662 1.0 13.04385110243475 -6.819024915812128 5.0897940053351025 0.8800027134320153 0.8293392972769044 0.09062365618840418 0.0779341171828495 0.5515064286163186 29.04879714123315 0.027701775088158027 0.024763386805231526 1.516963335596685e-07 6.819024915812128 -0.05066341615511094 RLQLS(ph)PWESSVVNR ddPTM_PC-9_AZD4547_30min_R2 1 RLQLSPWESSVVNR 14 1 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 RLQLS(1)PWESSVVNR 83.404 0.022458000000000002 0.0 10659.0 7794.4 10321.0 15583.0 12456.0 10948.0 8853.2 13244.0 9219.3 10506.0 True False 14048.340279027017 10313.787372200524 10184.136796378403 11990.58010495003 10726.699406210588 10263.419829307566 9641.117649079048 11197.444116843584 9706.613376426023 10138.18813777752 1.3856854980506088 1.0173205736603639 1.004532235738422 1.1827143018060609 1.0580489590876816 1.0123524726339808 0.9509704809238784 1.1044817835959269 0.9574307799888485 1.0 13.307512221416479 -4.759500121863196 24.99408757458329 1.0367704512626705 1.3856859406129942 0.7216042888589883 0.06584796318596418 27.465385497213855 353893.9173854159 0.01653360171204424 0.10446282734705488 1.7398022098490604e-05 4.759500121863196 0.3489154893503237 RLQSIGTENTEENR ddPTM_PC-9_AZD4547_30min_R2 4 RLQSIGTENTEENR 14 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ;;; 203.74 7.472399999999998e-11 20307700.0 31657.9 29411.699999999997 46236.100000000006 43051.299999999996 41591.3 49922.1 39380.9 47674.6 36555.6 42622.6 False True 41724.45367477337 38918.456847858746 45622.97910386895 33126.48792095457 35817.06591309621 46800.463195165794 42885.723809087904 40307.58602332158 38487.85438626348 41130.395747309754 1.014443282557097 0.9462213076421545 1.1092278174068637 0.8054016334895415 0.8708174395681306 1.1378558933079779 1.0426771498276421 0.9799950934330119 0.9357521046653408 1.0 15.327917332737963 -6.73922047974794 24.999877114033644 1.0194696776577572 0.9499547808956698 0.1325888649233492 0.08955378884764895 554.9308895132352 624386.6824531107 0.031152718811418494 0.03112994429200961 1.822969994020622e-07 6.73922047974794 -0.06951489676208744 RLQSIGTENTEENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RLQSIGTENTEENR 14 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ;;; 201.08 1.3649e-12 16687300.0 28804.3 33319.100000000006 38348.2 33035.7 54478.5 33308.899999999994 37752.9 32969.4 35163.2 30747.6 False True 33680.299079142664 36626.800049739366 39262.56652435837 31184.816832184457 43803.829002184466 31562.12264703277 34176.67200467358 32103.988183966816 35677.39527776126 36321.8964821323 0.9272725914989293 1.0083944836899432 1.080961357391475 0.8585679673286082 1.2059895887796697 0.8689558008778262 0.9409385333578599 0.8838742272105646 0.9822558493142534 1.0 15.148551911857169 RLQSIGTENTEENR ddPTM_PC-9_Lapatinib_30min_R1 4 RLQSIGTENTEENR 14 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ;;; 132.51 8.2479e-06 29532600.0 38270.0 46647.1 47732.7 42375.4 45725.9 47835.0 50778.5 47002.8 53833.0 38908.100000000006 False True 37724.26278214153 46539.091505939294 43808.3016595504 45491.82827619046 43036.39246257829 45789.20855883129 53407.562268891335 49186.72168015754 47769.760653378784 45633.3132432156 0.8266825286404133 1.0198490575929935 0.9600070331527697 0.9968995245584941 0.9430915575470865 1.003416261159579 1.1703634575960042 1.077868736333105 1.0468177140409767 1.0 15.477799785163485 -7.025569996509608 8.881986921789187 1.0813151094555589 0.9580538542935374 0.4671927961018766 0.06209563152942396 0.2796874493755609 91.01433607383494 0.022520652506803237 0.01793889364195404 9.428226417357067e-08 7.025569996509608 -0.12326125516202147 RLS(ph)APLPSSCGDPEK ddPTM_PC-9_AZD4547_30min_R2 3 RLSAPLPSSCGDPEK 15 1 H0YKX0;Q96EP0-3;Q96EP0 H0YKX0 RNF31 E3 ubiquitin-protein ligase RNF31 1 RLS(1)APLPSSCGDPEK;RLS(1)APLPSSCGDPEK;RLS(0.999)APLPSSCGDPEK 136.39 4.6171e-05 19653600.0 77583.0 74443.0 90414.0 88952.0 77826.0 83193.0 64469.0 80112.0 71929.0 73529.0 True False 102252.78017335142 98505.24393779185 89215.05128454193 68445.49069470025 67021.20327454613 77990.9285586027 70206.61610699829 67732.5311906202 75731.02009403615 70954.77209048573 1.4410980003283305 1.3882821554577347 1.2573509667647105 0.9646354808583488 0.9445623077906123 1.0991639640409816 0.9894558750391962 0.9545873969441219 1.0673139785081611 1.0 16.11461209610811 -5.569993948331953 2.8605912556511273 1.0014830746206167 1.410668596930224 0.9206220955487189 0.04960551021492542 0.06635465113645464 1.0947390019342333 0.014552991065436763 0.03024526147071827 2.691572309327824e-06 5.569993948331953 0.40918552230960725 RLS(ph)APLPSSCGDPEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RLSAPLPSSCGDPEK 15 1 H0YKX0;Q96EP0-3;Q96EP0 H0YKX0 RNF31 E3 ubiquitin-protein ligase RNF31 1 RLS(0.996)APLPS(0.002)S(0.002)CGDPEK;RLS(1)APLPSSCGDPEK 114.58 0.00025488 11441500.0 64313.0 71841.0 63047.0 62563.0 66840.0 44798.0 52801.0 55685.0 41542.5 42919.0 True False 75199.92066034941 78972.89969937151 64550.27958707895 59057.7979419827 53743.18181495468 42448.71401762816 47799.30703386415 54223.3277531345 42149.980471811396 50699.874953382954 1.4832368073785887 1.557654723448229 1.2731841971293032 1.1648509586322375 1.0600259244104637 0.8372548069725716 0.9427894462819525 1.069496281854566 0.8313626120491828 1.0 15.629694568506729 -5.7340000460444855 1.1579287420999087 0.9424037509259826 1.5537425205188005 0.8895395832094231 0.07893907815207173 0.16241342259784086 0.4199549791458983 0.028337810149730146 0.08030168403867578 1.8450152235684658e-06 5.7340000460444855 0.6113387695928179 RLS(ph)APLPSSCGDPEK ddPTM_PC-9_Lapatinib_30min_R1 4 RLSAPLPSSCGDPEK 15 1 H0YKX0;Q96EP0-3;Q96EP0 H0YKX0 RNF31 E3 ubiquitin-protein ligase RNF31 1 RLS(0.998)APLPS(0.001)S(0.001)CGDPEK;RLS(0.984)APLPS(0.015)S(0.001)CGDPEK;RLS(1)APLPSSCGDPEK;RLS(1)APLPSSCGDPEK 144.08 0.00015274 24942300.0 154948.0 200038.0 223983.0 182496.0 208627.0 183516.0 186649.0 181653.0 198463.0 190094.0 True False 152738.41310601673 199574.82430129798 205567.98233938278 195917.36462880924 196355.9700364634 175667.44847669028 196312.7719394288 190093.2615368802 176110.0070319602 222951.49461566683 0.6850746319028435 0.8951490755661157 0.9220300706830852 0.8787443428739504 0.8807116111733186 0.7879177880350756 0.880517855589356 0.85262160661704 0.7899027873105137 1.0 17.766370345617595 -11.677247914268438 2.3761887586803243 1.3548903642981285 0.8475206369018694 0.3349733541467177 0.06653761621283436 5519377.469209653 1705336.3717276144 10513663.150055517 0.01694077523418653 2.1025778538064332e-12 11.677247914268438 -0.5073697273962591 RLS(ph)AQAHPAGK ddPTM_PC-9_Lapatinib_30min_R1 1 RLSAQAHPAGK 11 1 H7C3T2;Q2TAZ0;Q2TAZ0-3 H7C3T2 ATG2A Autophagy-related protein 2 homolog A 1 RLS(1)AQAHPAGK 53.038000000000004 0.044212 7150600.0 46443.0 39652.0 38177.0 37915.0 22077.0 25505.0 21714.0 21054.0 35012.0 36053.0 True False 45780.71430339691 39560.18823021162 35038.2344274817 40703.39558073222 20778.474265052006 24414.210605058906 22838.244672582026 22032.245701405813 31068.579867295142 42284.71301239718 1.0826776639107083 0.9355671450013916 0.828626516093631 0.9626030941441805 0.49139447296142463 0.5773767601993908 0.5401064130643675 0.5210451752373564 0.734747327200408 1.0 15.367848566598086 -6.250576692572463 24.94830253526402 0.6116269399298356 0.9423298036743993 0.4925388274798005 0.15100468402682357 544.5549359403666 1250677.3285712965 0.0427744640512955 0.05466222209080256 5.615950968610873e-07 6.250576692572463 0.3307028637445637 RLS(ph)ASSTGSTR ddPTM_PC-9_AZD4547_30min_R2 1 RLSASSTGSTR 11 1 P56945-6;A0A2R8Y6M6;A0A2R8Y5C9;A0A2R8Y8C4;A0A2R8YFS8;A0A2R8Y5E4;A0A2R8Y4C2;A0A2R8YFK2;A0A2R8Y596;P56945;P56945-8;P56945-2;P56945-3;P56945-5;P56945-7;P56945-4 P56945-6 BCAR1 Breast cancer anti-estrogen resistance protein 1 1 RLS(0.528)AS(0.212)S(0.212)T(0.047)GS(0.001)TR 86.803 0.015746 25834000.0 34474.0 22824.0 33475.0 48568.0 39236.0 35746.0 31202.0 45990.0 28878.0 33128.0 True False 45436.01489625458 30201.411652353592 33031.09962782354 37371.39796811993 33788.758662658816 33510.796969165865 33978.91755371668 38883.302245064624 30404.432124394552 31968.198803378447 1.4212879235302063 0.9447329778605438 1.03324869289579 1.1690179417981617 1.056949090891163 1.0482541470439177 1.06289746765857 1.2163119506425046 0.9510836788584212 1.0 14.964349839631645 -4.74944202976729 24.99939800781249 1.0635677269395527 1.421288731537177 0.6450329603501148 0.08152534067269264 354.1693410923595 737952.608242456 0.01979052053889713 0.3236860435495504 1.7805655653652098e-05 4.74944202976729 0.35772100459762424 RLS(ph)ASSTGSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RLSASSTGSTR 11 1 P56945-6;A0A2R8Y6M6;A0A2R8Y5C9;A0A2R8Y8C4;A0A2R8YFS8;A0A2R8Y5E4;A0A2R8Y4C2;A0A2R8YFK2;A0A2R8Y596;P56945;P56945-8;P56945-2;P56945-3;P56945-5;P56945-7;P56945-4 P56945-6 BCAR1 Breast cancer anti-estrogen resistance protein 1 1 RLS(0.855)AS(0.064)S(0.064)T(0.017)GS(0.001)TR;RLS(0.989)AS(0.002)S(0.002)T(0.006)GS(0.001)TR 101.72 0.005313399999999999 103418000.0 38301.3 42891.0 47625.0 54417.0 62935.0 61602.0 64330.0 60163.0 58623.0 46402.0 True False 44784.95360484257 47148.935023256 48760.56061881827 51368.19191229435 50603.33853267768 58371.48267587682 58236.19669113234 58583.784997967705 59480.25047118009 54814.31528197009 0.8170302479282004 0.8601573289881915 0.8895588746842732 0.9371309601889843 0.9231774267792866 1.0648948614172833 1.062426783798352 1.0687679796164031 1.0851225663443569 1.0 15.742265095532009 -6.303220970095249 0.9174723773653628 1.06830930277553 0.8387807199139538 0.8700109451082998 0.0335627427400683 0.18882701354709105 0.3408924365399728 0.016536069899037227 0.025386572267653208 4.974838995481232e-07 6.303220970095249 -0.22952858286157618 RLS(ph)ASSTGSTR ddPTM_PC-9_Lapatinib_30min_R1 2 RLSASSTGSTR 11 1 P56945-6;A0A2R8Y6M6;A0A2R8Y5C9;A0A2R8Y8C4;A0A2R8YFS8;A0A2R8Y5E4;A0A2R8Y4C2;A0A2R8YFK2;A0A2R8Y596;P56945;P56945-8;P56945-2;P56945-3;P56945-5;P56945-7;P56945-4 P56945-6 BCAR1 Breast cancer anti-estrogen resistance protein 1 1 RLS(0.818)AS(0.078)S(0.078)T(0.024)GS(0.001)TR;RLS(0.837)AS(0.054)S(0.054)T(0.054)GS(0.001)TR 86.288 0.016159 93794000.0 42315.0 39800.0 48393.0 33642.0 43796.0 48926.0 38558.0 46333.0 57860.0 36093.0 True False 41711.580340379354 39707.8455453047 44414.31434238208 36116.14490642211 41220.005386248915 46833.54903207651 40554.344574257055 48485.80032693239 51343.197507188845 42331.62695910056 0.9853526390724298 0.9380184131280643 1.0491993228914576 0.8531716709427765 0.9737401642056975 1.1063489026142452 0.9580152592159838 1.145380034029351 1.212880326021841 1.0 15.369448317313264 -7.259176328792404 1.167619424097792 1.1211308820734924 0.9609274539646743 0.34096088517443224 0.08251704162838912 0.5280568111795496 1.4023666376102504 0.05515465635332201 0.03149971381985324 5.505841072370803e-08 7.259176328792404 -0.16020342810881816 RLS(ph)DEHEPEQR ddPTM_PC-9_AZD4547_30min_R2 1 RLSDEHEPEQR 11 1 Q9UK59-2;Q9UK59 Q9UK59-2 DBR1 Lariat debranching enzyme 1 RLS(1)DEHEPEQR 75.911 0.007775 8106400.0 8297.9 8865.5 13768.0 21175.0 15886.0 17161.0 12338.0 15800.0 13977.0 16418.0 True False 10936.459592957894 11731.09950069842 13585.427324148617 16293.430900488795 13680.503112320268 16087.919957138021 13436.058098126932 13358.47304788044 14715.795685388965 15843.210817250276 0.6902931305471329 0.7404496245120629 0.8574920501188208 1.0284172247931154 0.8634930930430322 1.0154456784493016 0.8480640858163417 0.8431670323628829 0.9288392267914678 1.0 13.951577124102318 -5.306702684732485 2.9417272828168883 0.9238990414460573 0.7041114319322096 0.6333079394458545 0.06515025852929246 0.16651955909785138 2.8324624465907227 0.017532516918774305 0.048586187940783225 4.9351154322945765e-06 5.306702684732485 -0.21978760951384768 RLS(ph)DEHEPEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLSDEHEPEQR 11 1 Q9UK59-2;Q9UK59 Q9UK59-2 DBR1 Lariat debranching enzyme 1 RLS(1)DEHEPEQR 86.803 0.0049139 20044000.0 126400.0 161220.0 156820.0 185340.0 188850.0 175000.0 163590.0 163330.0 134610.0 92203.0 True False 147797.02348620293 177224.85613413865 160559.18354316163 174956.00068038734 151846.19817106824 165822.69193010664 148093.57091096466 159042.7605624398 136578.41659289962 108918.67402145383 1.3569484279352426 1.627130129212099 1.4741198879407595 1.6062993995494848 1.3941245570172744 1.5224450115638055 1.3596710779071228 1.4601973627691518 1.253948579708174 1.0 16.732891798634085 -8.752281907759052 0.6266816107820931 0.9891797674823294 1.5111356308293196 0.7519642014019301 0.08666356073870078 0.5009191664703339 0.4141155844452021 0.0870120665193614 0.03370701657145202 1.7689603240415315e-09 8.752281907759052 0.5219558633469902 RLS(ph)DEHEPEQR ddPTM_PC-9_Lapatinib_30min_R1 1 RLSDEHEPEQR 11 1 Q9UK59-2;Q9UK59 Q9UK59-2 DBR1 Lariat debranching enzyme 1 RLS(1)DEHEPEQR 66.78399999999999 0.01895 25806000.0 51502.0 107190.0 144990.0 155600.0 145040.0 133650.0 124740.0 109210.0 145560.0 100440.0 True False 50767.57203568993 106941.80814073412 133069.4818775851 167043.34306638342 136509.03235961156 127934.10105336676 131198.4268424924 114284.29529070621 129165.49998524731 117800.92017211246 0.43096074259450795 0.9078181051938077 1.129613263488643 1.4180139070418598 1.1588112568235096 1.0860195392909433 1.1137300680742186 0.9701477299475395 1.096472759266487 1.0 16.845991282896854 -4.809186140986718 2.3814777427079776 1.1294853388103965 0.2920734100595579 0.7709746146733973 0.11424431078197966 0.2607710304571208 1.915417346162689 0.032862543629123185 0.4483604808109337 1.551721790976128e-05 4.809186140986718 -0.8374119287508386 down RLS(ph)DSPVFDAPPSPPDSLSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RLSDSPVFDAPPSPPDSLSDR 21 1 P47974 P47974 ZFP36L2 Zinc finger protein 36, C3H1 type-like 2 1 RLS(0.851)DS(0.149)PVFDAPPSPPDSLSDR;RLS(0.5)DS(0.5)PVFDAPPSPPDSLSDR 94.00299999999999 0.00017931 5513200.0 19784.0 24638.8 27487.6 24364.8 25430.7 20149.1 24752.8 20221.6 20215.2 18706.6 True False 23133.040448188563 27084.777231843527 28143.0086313035 22999.719247747395 20447.736890807446 19092.445725536672 22408.035589247014 19690.804426556253 20510.80905659894 22097.958498635875 1.0468406142412017 1.2256687527725918 1.2735569502060922 1.0408074234172893 0.9253224406258932 0.8639913830372731 1.0140319337929014 0.8910689386882404 0.9281766484385917 1.0 14.431625473150877 -5.98646093226591 4.190653079634153 0.9342110946028702 1.1856784155837468 0.718596448271904 0.0684555248124559 0.10463029031600861 4.347320538104767 0.02010012516949958 0.029248452268845423 1.0316658806082572e-06 5.98646093226591 0.25146732098087654 RLS(ph)DSPVFDAPPSPPDSLSDR ddPTM_PC-9_Lapatinib_30min_R1 3 RLSDSPVFDAPPSPPDSLSDR 21 1 P47974 P47974 ZFP36L2 Zinc finger protein 36, C3H1 type-like 2 1 RLS(0.5)DS(0.5)PVFDAPPSPPDSLSDR;RLS(0.5)DS(0.5)PVFDAPPSPPDSLSDR;RLS(0.5)DS(0.5)PVFDAPPSPPDSLSDR 87.49600000000001 0.00020336 5547100.0 15918.099999999999 21060.0 26068.9 17381.1 20528.699999999997 21097.8 21939.5 22880.7 22617.800000000003 16887.6 True False 15691.104974977974 21011.236863922535 23925.615670864063 18659.364075649886 19321.24222697708 20195.49627537391 23075.419959202056 23943.820852102024 20070.34518800719 19806.599158687462 0.7922160108993587 1.0608200173883309 1.2079618252066227 0.9420781390158854 0.9754951908794752 1.019634724445659 1.1650369543163517 1.2088809724611362 1.013316068407637 1.0 14.273693566788925 -7.158514396962918 6.617056601073654 1.1138602585894077 1.007353751390795 0.14080627994670625 0.11377126470414778 0.47814584858117576 26.378881225436775 0.04461191275344322 0.03447384382444393 6.942015883888245e-08 7.158514396962918 -0.10650650719861265 RLS(ph)EDSSR ddPTM_PC-9_AZD4547_30min_R2 2 RLSEDSSR 8 1 Q9NYP9 Q9NYP9 MIS18A Protein Mis18-alpha 1 RLS(0.976)EDS(0.024)SR;RLS(0.828)EDS(0.164)S(0.008)R 88.155 0.016434999999999998 18857200.0 47322.0 35332.0 53359.0 82699.0 60914.0 61914.0 43394.0 52109.0 50110.0 68589.0 True False 62369.41164125306 46752.37804508226 52651.42479584877 63634.02323681339 52457.14255217661 58042.50779245056 47255.9819346831 44056.751395696345 52758.71229840746 66187.71998686688 0.9423109249514644 0.7063603045150818 0.7954863048054228 0.9614173633634727 0.7925509832123734 0.8769377129770822 0.7139690254334148 0.66563331392044 0.797107262629321 1.0 16.014275953720478 -7.253980159933691 24.76680407419586 0.7663135096982755 0.8400457139655598 0.025785446439121618 0.10821156668420522 1251.1869896274004 4154315.4862898802 0.04071056925625552 0.030870380392008158 5.5721120367560284e-08 7.253980159933691 0.07373220426728433 RLS(ph)EDSSR ddPTM_PC-9_Lapatinib_30min_R1 2 RLSEDSSR 8 1 Q9NYP9 Q9NYP9 MIS18A Protein Mis18-alpha 1 RLS(0.959)EDS(0.036)S(0.005)R;RLS(0.972)EDS(0.027)S(0.001)R 87.713 0.016921000000000002 14132500.0 50955.0 47796.0 60115.0 45626.0 59316.0 50583.0 58679.0 50782.0 64737.0 50602.0 True False 50228.37235599744 47685.33129857746 55172.57675061059 48981.48824387418 55827.14949974291 48419.68300473218 61717.11150144795 53141.51710880543 57445.637349168406 59348.488277073266 0.8463294317035032 0.8034801337475455 0.9296374406881758 0.8253198972010896 0.9406667485633214 0.815853687438186 1.039910422205138 0.8954148395610334 0.9679376681168146 1.0 15.856923661599513 -6.667073616360013 0.29899341357872866 1.0065585666630414 0.7940249574043287 0.4242131151132704 0.059352666139242824 2.4933202506392704 0.44640655635858023 0.07833585001947797 0.18631195336321318 2.1524168520680872e-07 6.667073616360013 -0.21253360925871279 RLS(ph)EGVEPWR ddPTM_PC-9_AZD4547_30min_R2 2 RLSEGVEPWR 10 1 A0A3B3ITI3;A0A3B3IS53;A0A3F2YNX6;Q92794 A0A3B3ITI3 KAT6A Histone acetyltransferase KAT6A 1 RLS(1)EGVEPWR;RLS(1)EGVEPWR 68.277 0.018982 4609800.0 13631.5 10782.6 13746.900000000001 22732.8 19357.4 18652.5 14651.8 19556.9 15282.900000000001 15110.1 True False 17966.033447186106 14267.864584764628 13564.607123935113 17492.10417825887 16669.959143045973 17486.156226357252 15955.781815702396 16534.830477853986 16090.722893341277 14581.099998156498 1.2321452736389962 0.9785177103626288 0.9302869554183223 1.1996422890228042 1.143257994606276 1.1992343669934395 1.0942783341256626 1.1339906097581458 1.1035328538570919 1.0 13.831811940231011 -4.715294613365217 23.85560612612541 1.0952785771880047 1.2321487657198247 0.1954940963341567 0.08689172447476695 14836.104696659506 7668787.000469736 0.023031749997258634 14.813075025199337 1.926217777012131e-05 4.715294613365217 0.13687018853181998 RLS(ph)EGVEPWR ddPTM_PC-9_Lapatinib_30min_R1 2 RLSEGVEPWR 10 1 A0A3B3ITI3;A0A3B3IS53;A0A3F2YNX6;Q92794 A0A3B3ITI3 KAT6A Histone acetyltransferase KAT6A 1 RLS(1)EGVEPWR;RLS(1)EGVEPWR 74.53699999999999 0.0271 1426500.0 8228.8 7882.7 9010.6 6575.200000000001 13412.3 13373.3 16532.1 13058.2 15436.3 11632.3 True False 8111.455803022892 7864.448092461646 8269.783249921857 7058.762142224202 12623.414883596353 12801.355133684929 17388.051245813444 13664.9316433028 13697.70134255478 13642.927555934531 0.5945539012625258 0.5764487174925071 0.6061589945425303 0.517393507609275 0.9252717081316831 0.938314381660443 1.2745102672812936 1.0016128567184759 1.0040148118060204 1.0 13.735865636612461 -6.444980437453803 2.4100575431706504 1.0601037105734668 0.5732643425487541 0.8600565170017844 0.08952165688958631 0.10296576097027782 1.1800839067296118 0.031248982256572213 0.03523360873096231 3.5893810244211203e-07 6.444980437453803 -0.4868393680247126 RLS(ph)EQLAHTPTAFK ddPTM_PC-9_AZD4547_30min_R2 1 RLSEQLAHTPTAFK 14 1 Q9UBF8-2;A0A0B4J1S8;Q9UBF8;F8W860;Q9UBF8-3 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 RLS(0.995)EQLAHT(0.003)PT(0.002)AFK 59.733000000000004 0.026805000000000002 28555000.0 51587.0 67023.0 63320.0 77985.0 64193.0 72341.0 65808.0 79264.0 60372.0 70505.0 True False 67990.59292374198 88686.87404380018 62480.335427447 60006.76310623934 55280.91000183657 67817.5058341193 71664.7845130115 67015.57010551862 63563.14066811924 68036.64141005187 0.9993231810777906 1.3035163436315274 0.9183336233616026 0.8819771502914577 0.8125167388652029 0.996779153535639 1.0533263110548488 0.9849923323172387 0.9342486541190184 1.0 16.05402430449172 -5.285935615072963 24.942658868032957 0.9455754720305952 1.1514197904180685 0.43076756187424126 0.09361320689032972 600.4715510689368 611413.7335133177 0.024911985103807956 0.05189310131799385 5.176835737696446e-06 5.285935615072963 0.2058443183874733 RLS(ph)EQLAHTPTAFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLSEQLAHTPTAFK 14 1 Q9UBF8-2;A0A0B4J1S8;Q9UBF8;F8W860;Q9UBF8-3 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 RLS(1)EQLAHTPTAFK 71.637 0.011293000000000001 19732000.0 87130.0 103830.0 102430.0 83996.0 107110.0 69050.0 72613.0 80742.0 69756.0 67225.0 True False 101879.38810405757 114137.55621143516 104872.31966793803 79289.97643870638 86122.5643955683 65428.89644442214 65734.57096740551 78622.6080532206 70776.0495346134 79412.36034719263 1.2829160052495427 1.4372769643469 1.3206044904021728 0.998458880859967 1.0844982320011458 0.8239132568074482 0.8277624626696963 0.9900550457067486 0.8912472721523313 1.0 16.277075956486392 -5.841347039827542 1.8128533579592847 0.9195801140011204 1.378739875822009 0.8258446513184263 0.08456774100011637 0.13209062574734962 0.8860076154354519 0.027011294879603024 0.05124417676087329 1.4409634336985261e-06 5.841347039827542 0.4591597618208887 RLS(ph)EQLAHTPTAFK ddPTM_PC-9_Lapatinib_30min_R1 2 RLSEQLAHTPTAFK 14 1 Q9UBF8-2;A0A0B4J1S8;Q9UBF8;F8W860;Q9UBF8-3 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 RLS(0.988)EQLAHT(0.011)PT(0.001)AFK;RLS(0.958)EQLAHT(0.042)PTAFK 87.419 0.002804 47775000.0 114860.0 140317.0 145272.0 148992.0 145507.0 140151.0 119773.0 120309.0 142823.0 103558.0 True False 113222.07533725571 139992.10460755092 133328.29692613636 159949.36870274218 136948.5643377687 134157.0684379381 125974.25988621 125898.995349598 126736.769747135 121457.86231763886 0.9321922284549619 1.1525981269243892 1.0977329452535045 1.3169124307855806 1.1275397222093229 1.1045564764435591 1.0371848926235814 1.0365652165056602 1.0434628712276413 1.0 16.890096357243273 -7.159022653478463 2.6509327917900434 1.0303880727104207 1.1351607591761932 0.2099840419852923 0.08782762604425923 0.4632334205041024 6.335724316216779 0.03959969427591395 0.028634067017296327 6.933896367868561e-08 7.159022653478463 0.10477268646577254 RLS(ph)ESQLSFR ddPTM_PC-9_AZD4547_30min_R2 3 RLSESQLSFR 10 1 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 RLS(0.999)ES(0.001)QLSFR;RLS(1)ESQLSFR;RLS(0.988)ES(0.012)QLSFR 110.98 0.00076182 51768500.0 61679.0 55436.0 57879.1 96339.0 81464.0 75039.0 59040.0 72027.0 59424.7 56781.0 True False 81291.63899710163 73354.60288993496 57111.58531646786 74129.53197271265 70154.12977099692 70346.79946761159 64294.44562436484 60896.882165802774 62565.768324070516 54793.114472791305 1.4836104824351377 1.3387558563833921 1.0423131786901407 1.3528986750611385 1.2803457231078452 1.2838620353026986 1.1734037432073992 1.1113966189317899 1.1418545728978207 1.0 15.741706989157013 -1.5228787457809048 0.08033068001690626 0.7923797153186631 2.358074525969472 0.5374934374481175 0.0983209755863738 169.8096379977504 0.9978803544732419 2.923629427362271 29.508702948404935 0.029999999965422044 1.5228787457809048 1.565694810650809 RLS(ph)ESQLSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RLSESQLSFR 10 1 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 RLS(0.99)ES(0.01)QLSFR;RLS(0.997)ES(0.003)QLSFR;RLS(0.966)ES(0.015)QLS(0.019)FR 110.98 0.00076182 34583800.0 70438.3 56677.5 72932.6 79344.0 71328.5 84204.6 89662.0 111556.0 69054.9 51760.3 True False 82362.11297015961 62304.06763145167 74671.58978242592 74898.61291671864 57352.192460921586 79788.76254227351 81168.5662633345 108627.77320335236 70064.69727346417 61144.032655690644 1.3470180063842128 1.0189721698974832 1.2212408396893049 1.224953763492861 0.9379851143263421 1.3049313085313423 1.327497757964451 1.7765883028201352 1.145895915436374 1.0 15.899924085528134 -6.983957795544283 24.47695691071784 1.3684974249710167 1.1479295899518671 0.10095633156550876 0.2156875241585486 307.7687356835577 469586.6620102401 0.0730672967034983 0.06441973850350453 1.03762924705496e-07 6.983957795544283 -0.22056783501914956 RLS(ph)ESQLSFR ddPTM_PC-9_Lapatinib_30min_R1 4 RLSESQLSFR 10 1 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 RLS(0.984)ES(0.015)QLS(0.001)FR;RLS(0.983)ES(0.017)QLSFR;RLS(0.989)ES(0.011)QLSFR;RLS(0.995)ES(0.005)QLSFR 117.95 0.00073963 69909300.0 134962.3 121259.4 163644.0 135731.2 147931.0 161761.7 173443.0 144421.1 175744.0 168870.1 True False 133037.71285294517 120978.63130945506 150189.8220041076 145713.3252340098 139229.98942353603 154843.52917594017 182423.0298768833 151131.43154114622 155949.86005363625 198059.071779736 0.6717072419732336 0.6108209546897045 0.7583082191313893 0.7357063926668274 0.7029720384551507 0.78180478068757 0.9210536444387574 0.7630624044791111 0.787390643873511 1.0 17.595571257536953 -6.127733640484838 0.05792951173157547 1.4630334092416861 7.36734298717501e-10 0.7223230283642091 0.05697510930305242 57.726654313350686 0.9081604721227023 8.792822805489545 14.18678602654513 7.451888696272224e-07 6.127733640484838 -1.463033408504952 RLS(ph)ESSALK ddPTM_PC-9_AZD4547_30min_R2 4 RLSESSALK 9 1 Q96S55-2;Q96S55 Q96S55-2 WRNIP1 ATPase WRNIP1 1 RLS(0.464)ES(0.464)S(0.072)ALK;RLS(0.848)ES(0.13)S(0.022)ALK;RLS(0.792)ES(0.201)S(0.007)ALK;RLS(0.987)ES(0.011)S(0.002)ALK 87.667 0.0049113 102500000.0 104665.0 119904.0 113583.0 120404.0 119871.0 133787.0 127801.0 159431.0 138733.0 99129.0 True False 137946.29283275755 158660.6231494832 112076.81520618613 92646.71802325624 103228.98077407447 125421.27774055293 139175.0414166577 134794.60230991337 146066.14315096725 95658.52388251944 1.4420700553792023 1.658614587700916 1.1716343788017303 0.9685150289067593 1.0791404318642057 1.3111354080122108 1.454915210562751 1.409122750790697 1.5269537645213367 1.0 16.545605908655396 -7.004875137648131 24.724575399860388 1.3820106267604642 1.2574481819013283 0.02147199025065727 0.22150632688990834 635.4863966880042 3222924.962466048 0.08621759299771896 0.07403061420470232 9.888373506516054e-08 7.004875137648131 -0.12456244485913581 RLS(ph)ESSALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RLSESSALK 9 1 Q96S55-2;Q96S55 Q96S55-2 WRNIP1 ATPase WRNIP1 1 RLS(0.475)ES(0.475)S(0.051)ALK;RLS(0.886)ES(0.095)S(0.02)ALK;RLS(0.735)ES(0.233)S(0.033)ALK 122.55 0.00071044 55001000.0 69139.0 113519.0 101221.0 79997.0 117556.0 105063.0 153205.0 101540.0 108628.0 109770.0 True False 80842.8671425047 124788.41609906532 103634.49252278039 75515.02744377322 94521.74568280682 99553.31132715895 138692.3132918536 98874.68259052324 110216.47899601434 129670.43206115808 0.6234487373680978 0.9623505845974957 0.7992145231219864 0.5823611924741419 0.7289383106105974 0.7677410319740848 1.0695754698067208 0.7625075433070952 0.8499738702500164 1.0 16.984490022786403 -7.0325210183618685 24.73528434888997 0.9032853729409309 0.7464772581176162 0.32826026107833717 0.12305561988177711 809.7263775629508 615870.3681742032 0.047883104538001105 0.03712371586627421 9.278525841611992e-08 7.0325210183618685 -0.1568081148233147 RLS(ph)ESSALK ddPTM_PC-9_Lapatinib_30min_R1 4 RLSESSALK 9 1 Q96S55-2;Q96S55 Q96S55-2 WRNIP1 ATPase WRNIP1 1 RLS(0.789)ES(0.183)S(0.027)ALK;RLS(0.987)ES(0.013)SALK;RLS(0.616)ES(0.334)S(0.05)ALK;RLS(0.939)ES(0.06)SALK 96.82 0.0022839 90637000.0 64225.0 106545.0 111521.0 95522.0 175693.0 204626.0 239375.0 243374.0 200354.0 201630.0 True False 63309.1397225775 106298.30159860525 102352.17386350904 102547.00653205077 165359.08316572814 195874.62298650385 251768.6662291298 254682.04452046825 177788.0226988476 236481.4768449128 0.26771289052840425 0.44949948307501847 0.43281264659317376 0.43363652790151613 0.6992475071278943 0.8282873804740344 1.0646443416548963 1.0769640308339734 0.7518052790893343 1.0 17.851367658802538 -6.530162279342171 1.4814501245430955 0.9786766026790029 0.3818469486684012 0.8767451776400151 0.09780925796816911 0.1287566695238715 0.5792704798243055 0.04018325536171932 0.04417517404344789 2.9501066779445987e-07 6.530162279342171 -0.5968296540106017 down RLS(ph)EVIYEPFQLLSK ddPTM_PC-9_AZD4547_30min_R2 1 RLSEVIYEPFQLLSK 15 1 A0A087WVA8;Q8IWB9;Q8IWB9-2 A0A087WVA8 TEX2 Testis-expressed sequence 2 protein 1 RLS(0.982)EVIY(0.018)EPFQLLSK 81.788 0.0038797 784870.0 6394.4 7036.8 7828.5 10770.0 9802.5 7223.1 7913.4 13339.0 8430.4 7848.9 True False 8427.686188217505 9311.307987875995 7724.688974948971 8287.142894841283 8441.592078466545 6771.438415150847 8617.677269712885 11277.764049726402 8876.013732997286 7574.112400019224 1.1126962135122413 1.2293596260668591 1.0198804251874272 1.0941404691618055 1.114532189731581 0.8940240199146846 1.1377804836499406 1.488988208004119 1.1718883037667565 1.0 12.886861115674108 -7.535577574079106 24.9969554952984 1.260939845994283 1.0784839818519198 0.15860273786688628 0.13818980639932235 313.9775577564385 618039.9659832754 0.06261549449249097 0.03617871154320354 2.9135496673723384e-08 7.535577574079106 -0.18245586414236326 RLS(ph)EVIYEPFQLLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLSEVIYEPFQLLSK 15 1 A0A087WVA8;Q8IWB9;Q8IWB9-2 A0A087WVA8 TEX2 Testis-expressed sequence 2 protein 1 RLS(0.989)EVIY(0.011)EPFQLLSK 77.357 0.0059619 2602200.0 16123.0 13687.0 11102.0 9574.1 16782.0 7802.0 6744.2 12110.0 7218.9 8621.9 True False 18852.305456234542 15045.754905768226 11366.713784569467 9037.694216651003 13493.687570595004 7392.8493853639675 6105.340552220342 11792.125331605615 7324.462755682956 10184.982219077147 1.8509905123764403 1.4772490105664131 1.1160268658377095 0.8873549331998639 1.3248611809375999 0.7258578587910218 0.5994453815328843 1.1577953773466765 0.7191434013467154 1.0 13.314155841201153 -4.056980637142569 0.6623316364650356 0.87289926299317 3.890850663919461 0.7021565268293106 0.20046759284837465 4.156660125575537 0.6853179773169262 0.08634065258188363 11.779648171990267 8.770399227696763e-05 4.056980637142569 3.0179514009262913 RLS(ph)FAVPFR ddPTM_PC-9_AZD4547_30min_R2 1 RLSFAVPFR 9 1 P78527-2;P78527 P78527-2 PRKDC DNA-dependent protein kinase catalytic subunit 1 RLS(1)FAVPFR 93.839 0.002726 5420900.0 12929.0 14424.0 17226.0 20017.0 16340.0 17476.0 13282.0 18799.0 15856.0 15187.0 True False 17040.153060093846 19086.275923306537 16997.57198473154 15402.389909567137 14071.473048930719 16383.222957341892 14464.072269356613 15894.046508044583 16694.11578933443 14655.307752563034 1.1627291182004507 1.3023456242308238 1.1598236128312538 1.0509768999476279 0.960162235178568 1.117903713381704 0.986951111062613 1.084524922737628 1.1391173813060893 1.0 13.839135643614753 -5.612396387475174 3.5720925344515 1.0486913722951552 1.233170436531751 0.596366283402141 0.06197559062168629 0.14689409258507635 3.649931733739335 0.016889238189419474 0.0317630617369664 2.4412014122397383e-06 5.612396387475174 0.18447906423659588 RLS(ph)FAVPFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RLSFAVPFR 9 1 P78527-2;P78527 P78527-2 PRKDC DNA-dependent protein kinase catalytic subunit 1 RLS(1)FAVPFR;RLS(1)FAVPFR 80.834 0.0083026 8119600.0 21462.3 19492.4 17852.3 23171.0 26802.9 17998.6 20496.8 17879.3 18244.9 14688.2 True False 25095.443490252597 21427.476651216235 18277.966537224765 21872.803991395573 21551.06415122755 17054.721731275542 18555.194720018688 17409.98731968425 18511.69714654032 17351.054388272787 1.4463353597239648 1.234938014239562 1.0534210848637797 1.2606037363457832 1.2420607802251753 0.9829213458521846 1.0693986834920968 1.0033965043329756 1.0668917710875245 1.0 14.08273571465918 -1.5228787452803376 0.3192353627394674 1.0148343857312865 4.69913312512467 0.655921248156351 0.0846825447663711 38.57692497810523 0.5506253790892423 0.08540932940139592 82.91011969621347 0.029999999999999995 1.5228787452803376 3.684298739393384 RLS(ph)FAVPFR ddPTM_PC-9_Lapatinib_30min_R1 2 RLSFAVPFR 9 1 P78527-2;P78527 P78527-2 PRKDC DNA-dependent protein kinase catalytic subunit 1 RLS(1)FAVPFR;RLS(1)FAVPFR 80.834 0.010413 7123200.0 29126.0 30190.0 33030.0 25753.0 23931.5 30439.0 24544.0 23429.4 31981.0 21342.4 True False 28710.657898945745 30120.096909868058 30314.400899487122 27646.961529489585 22523.896221139268 29137.194926774657 25814.768225285665 24518.01545722983 28378.963005140107 25031.405403039582 1.1469854543388678 1.2032922812320619 1.2110546895543477 1.1044909818021003 0.8998254735790494 1.1640255294349755 1.0312951993558843 0.9794901669505377 1.1337343048942041 1.0 14.61145167381481 -5.975165070788495 6.1269540272988925 1.036639970458765 1.1852488090907567 0.47516388269095633 0.07178972951429402 0.14540266810957958 17.989037493939716 0.019889650673819644 0.029133872429937122 1.0588511904239215e-06 5.975165070788495 0.1486088386319917 RLS(ph)GGSHSYGGESPR ddPTM_PC-9_Lapatinib_30min_R1 2 RLSGGSHSYGGESPR 15 1 Q13905-2;Q13905;Q13905-4;Q13905-3 Q13905-2 RAPGEF1 Rap guanine nucleotide exchange factor 1 1 RLS(0.972)GGS(0.026)HS(0.002)YGGESPR;RLS(0.969)GGS(0.028)HS(0.003)YGGESPR 54.858999999999995 0.033316000000000005 3795100.0 14802.4 13958.1 15484.0 11604.7 17646.699999999997 16153.599999999999 14679.6 15700.9 17318.4 14891.5 True False 14591.315061572292 13925.780877033112 14210.965289968477 12458.148350144358 16608.75580074706 15462.748183880773 15439.637860165565 16430.421132953474 15367.819421163138 17465.475933323523 0.8354375865436663 0.7973318866429059 0.8136603516686567 0.7133013951469048 0.9509477934728437 0.885332197239377 0.884008996898119 0.9407370973272362 0.8798969738833095 1.0 14.09221833618376 -6.2744487307325105 24.9996865762773 0.9166423763629136 0.7921561331848577 0.6726982546883911 0.04547744685983434 474.915843843383 912629.8222845927 0.013583255019291586 0.015493826127818461 5.315587472968888e-07 6.2744487307325105 -0.1244862431780559 RLS(ph)GNEYVLSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RLSGNEYVLSTK 12 1 O60658-6;O60658-2;O60658 O60658-6 PDE8A High affinity cAMP-specific and IBMX-insensitive 3,5-cyclic phosphodiesterase 8A 1 RLS(1)GNEYVLSTK;RLS(0.724)GNEY(0.002)VLS(0.271)T(0.003)K 109.1 0.0019866 10633500.0 40273.0 42138.0 42909.0 40209.0 50507.0 36763.0 32257.0 33187.0 28451.0 31287.0 True False 47090.423471992464 46321.18215965964 43932.11329328869 37956.22008933684 40610.51591753319 34835.08356243724 29201.383439543857 32315.87641453307 28867.042050996093 36959.08543224429 1.2741230720744314 1.2533097509833822 1.1886688423020584 1.0269794191450046 1.0987965595626799 0.9425309948834935 0.7901002716389631 0.8743689416713668 0.7810540145512248 1.0 15.173641436663521 -6.186866362641552 0.7802529636628256 0.8454548066105383 1.288179193741259 0.8172620047944561 0.072945958309905 0.2818095956045163 0.3630617209894332 0.03957645662909541 0.07548767151258523 6.503297734357605e-07 6.186866362641552 0.4427243871307207 RLS(ph)GNEYVLSTK ddPTM_PC-9_Lapatinib_30min_R1 1 RLSGNEYVLSTK 12 1 O60658-6;O60658-2;O60658 O60658-6 PDE8A High affinity cAMP-specific and IBMX-insensitive 3,5-cyclic phosphodiesterase 8A 1 RLS(1)GNEYVLSTK 132.65 0.00011898 5944600.0 32829.0 30045.0 24650.0 20535.0 25357.0 17688.0 20396.0 15064.0 20151.0 17561.0 True False 32360.852439898725 29975.432648459315 22623.372151751657 22045.212402751855 23865.5511137801 16931.525472741887 21452.005081605537 15763.928433835716 17881.382180562785 20596.39545143836 1.5711900908194492 1.4553727480682046 1.0984141475187952 1.0703432284901249 1.1587246501481132 0.8220625552011076 1.04154171695647 0.7653731678925807 0.8681801736970451 1.0 14.330104254853392 -4.312610816100132 0.505992768199182 0.8824274824604625 2.5119790852634996 0.8234080127041695 0.1035169234205332 2.6103071332922987 0.36085587836436467 0.060524604885905525 2.788417315264383 4.868432846791377e-05 4.312610816100132 1.629551602803037 RLS(ph)GVSSVDSAFSSR ddPTM_PC-9_AZD4547_30min_R2 2 RLSGVSSVDSAFSSR 15 1 P57078-2;P57078 P57078-2 RIPK4 Receptor-interacting serine/threonine-protein kinase 4 1 RLS(0.927)GVS(0.059)S(0.013)VDSAFSSR;RLS(0.914)GVS(0.07)S(0.016)VDS(0.001)AFSSR 89.557 0.0020614 11771900.0 10584.0 11748.4 21495.1 25391.0 19670.8 21979.0 14678.0 20785.0 11990.900000000001 10720.3 True False 13949.491839123932 15545.840547516247 21210.060929351166 19537.49723703947 16939.848962723765 20604.649655494235 15984.313564946267 17573.1558417845 12624.714494092479 10344.985560005369 1.348430286172066 1.5027416381921155 2.0502745805031513 1.8885958925426796 1.6374937272232377 1.9917523843777643 1.5451267159562834 1.6987124573400934 1.2203704317288508 1.0 13.33664401097036 -8.373116229477938 2.1237734483713746 0.9950325022342662 1.7297767232738064 0.5746143506837578 0.2092356730842941 0.2211935312193772 1.9871522282924983 0.2068319652638583 0.0584197636766259 4.235296023886282e-09 8.373116229477938 0.7347442210395402 RLS(ph)GVSSVDSAFSSR ddPTM_PC-9_Lapatinib_30min_R1 1 RLSGVSSVDSAFSSR 15 1 P57078-2;P57078 P57078-2 RIPK4 Receptor-interacting serine/threonine-protein kinase 4 1 RLS(0.998)GVS(0.002)SVDSAFSSR 85.51 0.0026446 4332700.0 5400.6 8523.1 11097.0 6251.9 11599.0 9042.3 6197.2 10618.0 10385.0 5869.5 True False 5323.586453651253 8503.365285607699 10184.647495658755 6711.685581727022 10916.769624511393 8655.581907630814 6518.060692867519 11111.351042914739 9215.331941101907 6884.035254382862 0.7733235314653396 1.2352297702417863 1.4794589393153514 0.9749638596713881 1.585809662662754 1.257341310406576 0.9468372040537796 1.614075267241037 1.338652636218674 1.0 12.749038770359943 -4.769325116181106 4.74184630183804 1.2889413593364243 0.738978478483583 0.2938626230419519 0.2308529937876969 0.21670819212631237 11.686492757172566 0.055279021275695145 0.3977807265079762 1.7008847363136893e-05 4.769325116181106 -0.5499628808528413 RLS(ph)IIGPTSR ddPTM_PC-9_AZD4547_30min_R2 3 RLSIIGPTSR 10 1 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 RLS(1)IIGPTSR;RLS(1)IIGPTSR;RLS(1)IIGPTSR 85.163 0.0055381 45022800.0 58734.0 54429.0 60209.0 86040.0 109484.0 85563.0 72979.0 109934.0 91553.0 81330.0 True False 77410.1902569072 72022.10983289314 59410.589320138264 66204.80730474871 94284.03643140306 80212.73208394634 79473.98962094396 92946.22633200539 96392.30467084606 78482.66145492543 0.9863349282741363 0.9176817974535337 0.7569899926783098 0.843559661171427 1.2013358706693804 1.0220439852185 1.012631174168168 1.1842899388087997 1.2281987242010974 1.0 16.260086345707997 -6.251481156102014 24.90911457496119 1.1082232094196023 0.8705979092228402 0.5989304308757779 0.09293922123890747 481.06936550337 1203327.4951389576 0.02906600304871654 0.03707006240270225 5.604267335724911e-07 6.251481156102014 -0.2376253001967621 RLS(ph)IIGPTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RLSIIGPTSR 10 1 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 RLS(0.999)IIGPTS(0.001)R;RLS(1)IIGPTSR 78.529 0.0092929 37318000.0 43432.0 47515.0 41313.0 43415.0 42170.0 39572.0 30493.0 37789.0 31366.0 22669.0 True False 50784.17977889838 52231.975184304625 42298.05860042501 40982.59830332908 33907.091219877926 37496.77465747538 27604.4822897979 36797.07879075514 31824.66841135791 26778.71025229473 1.8964385999339368 1.9505037655735769 1.5795405455272211 1.530417182799802 1.2661958287170438 1.400245728946643 1.0308368860831303 1.3741169176585684 1.188431709799421 1.0 14.708798857111352 -5.451729078828373 0.5800045364670585 1.1545071603074932 2.20529644657018 0.8492017417197654 0.11992143145894771 0.6967790315554961 0.3019431335104606 0.06909631262729503 0.44714511594672535 3.534035609167677e-06 5.451729078828373 1.0507892862626869 RLS(ph)IIGPTSR ddPTM_PC-9_Lapatinib_30min_R1 2 RLSIIGPTSR 10 1 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 RLS(1)IIGPTSR;RLS(1)IIGPTSR 86.699 0.0050881 25999000.0 61647.0 46858.0 56764.0 61896.0 46109.0 42895.0 40392.0 39406.0 52369.0 47223.0 True False 60767.90247532477 46749.50317994695 52097.08303537658 66448.0383190031 43396.95927378189 41060.48084312884 42483.30012042613 41236.94661867564 46470.65174998222 55385.43262930777 1.097182049331304 0.8440757968406475 0.9406278973039722 1.1997385443160995 0.7835446472764022 0.7413588536528153 0.7670482670915467 0.7445449942527792 0.8390410536468718 1.0 15.757218950823114 -6.312618808049005 24.92949700373515 0.7939781712422441 1.0021127652680617 0.440381812118139 0.11285937397577639 311.01600350854204 151495.04040750195 0.03439767480163027 0.03900332422367548 4.868343258021473e-07 6.312618808049005 0.20813459402581758 RLS(ph)LDIQSPPNIGLR ddPTM_PC-9_AZD4547_30min_R2 2 RLSLDIQSPPNIGLR 15 1 Q9NSI6-3;Q9NSI6-2;Q9NSI6;H0Y5I9;H0Y463;H7BZR9 Q9NSI6-3 BRWD1 Bromodomain and WD repeat-containing protein 1 1 RLS(1)LDIQSPPNIGLR;RLS(1)LDIQSPPNIGLR 113.73 8.560700000000001e-05 10200100.0 25202.0 25145.0 26412.0 37942.0 25316.0 32992.0 28009.0 31960.0 21101.8 24247.7 True False 33215.71176583534 33272.62951272479 26061.759622705784 29195.058098056455 21801.310385968776 30929.005024526425 30501.746739377304 27021.31636773789 22217.198067821475 23398.795403425487 1.419547937966614 1.421980445534124 1.1138077483634243 1.2477162860179725 0.9317278949657876 1.3218203967883981 1.3035605557246752 1.1548165579405032 0.9495017877958354 1.0 14.514146639689873 -1.5228787541905136 0.4635881528268247 1.1140028984944201 9.911412982828358 0.39355192893472235 0.13659684178777962 104.16380445993796 1.215872649929516 0.0849317000817188 874.7272551489325 0.029999999384506853 1.5228787541905136 8.797410084333938 RLS(ph)LDIQSPPNIGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLSLDIQSPPNIGLR 15 1 Q9NSI6-3;Q9NSI6-2;Q9NSI6;H0Y5I9;H0Y463;H7BZR9 Q9NSI6-3 BRWD1 Bromodomain and WD repeat-containing protein 1 1 RLS(1)LDIQSPPNIGLR 74.744 0.046402 0.0 28372.0 27340.0 25783.0 27186.0 27661.0 22126.0 29785.0 22603.0 22646.0 21707.0 True False 33174.81922745682 30054.134516234648 26397.764502572012 25662.856558201198 22241.025616149946 20965.673609403097 26963.549175274 22009.695199858124 22977.154907977147 25642.307267482556 1.2937532836417716 1.172052662918785 1.0294613595886304 1.0008013822821904 0.8673566455680908 0.8176204032930384 1.051525858964608 0.8583352102550066 0.8960642530446106 1.0 14.646238459509025 -5.1559175034877365 1.119098601249433 0.9122424205074499 1.3577372289447107 0.7758414887360006 0.06714499711689084 0.4344511047293583 0.6900269533890776 0.02207920087435182 0.19644645203674557 6.9836504957857326e-06 5.1559175034877365 0.44549480843726086 RLS(ph)LDIQSPPNIGLR ddPTM_PC-9_Lapatinib_30min_R1 2 RLSLDIQSPPNIGLR 15 1 Q9NSI6-3;Q9NSI6-2;Q9NSI6;H0Y5I9;H0Y463;H7BZR9 Q9NSI6-3 BRWD1 Bromodomain and WD repeat-containing protein 1 1 RLS(1)LDIQSPPNIGLR;RLS(1)LDIQSPPNIGLR 77.969 0.005674 7911600.0 30905.0 28559.0 30737.0 26298.0 26551.0 28154.0 34025.0 27367.0 33268.0 32862.0 True False 30464.28903271712 28492.87339015973 28209.92250825116 28232.04264755627 24989.322381274433 26949.919050179487 35786.648014396385 28638.570728145358 29521.007512429303 38542.152914137434 0.7904148245320951 0.7392652261443449 0.7319238904763836 0.7324978111744409 0.6483634278797186 0.6992323213033109 0.9285067207875065 0.7430454337085203 0.7659408019628521 1.0 15.234149540487687 -10.296107088638108 0.3616413791392053 1.0959994552126497 0.7293973002285375 0.5581980087786664 0.06718267180554198 9.027592250941131 1.005953366222395 1.0284678720394873 0.05588138061800919 5.0569995077932456e-11 10.296107088638108 -0.3666021549841122 RLS(ph)LDSSCLDSSR ddPTM_PC-9_AZD4547_30min_R2 1 RLSLDSSCLDSSR 13 1 A0A0C4DH56;Q9BWT3-2;Q9BWT3 A0A0C4DH56 PAPOLG Poly(A) polymerase gamma 1 RLS(0.987)LDS(0.009)S(0.003)CLDSSR 62.081 0.023319 3808500.0 11428.0 16042.0 21126.0 21502.0 20831.0 19291.0 18642.0 22873.0 21219.0 27156.0 True False 15061.866282833345 21227.262781592024 20845.855436516827 16545.04610258842 17938.975219233507 18084.73072042128 20301.101885660733 19338.503419251218 22340.59302055295 26205.2767056431 0.5747646343146566 0.8100377271353483 0.7954831261914451 0.6313631521023235 0.6845558404414974 0.6901179073040231 0.7746951926399255 0.7379621912210842 0.8525226911930329 1.0 14.677569722249814 -8.575489477904469 1.0264533909621518 1.0007350926391583 0.7062976957440666 0.6527694446728503 0.06765613585430659 0.39078412648658156 0.8953986367820445 0.06505186891805557 0.021336237752885123 2.657727940260811e-09 8.575489477904469 -0.29443739689509163 RLS(ph)LDSSCLDSSR ddPTM_PC-9_Lapatinib_30min_R1 1 RLSLDSSCLDSSR 13 1 A0A0C4DH56;Q9BWT3-2;Q9BWT3 A0A0C4DH56 PAPOLG Poly(A) polymerase gamma 1 RLS(0.997)LDS(0.001)SCLDS(0.001)SR 73.758 0.034963 0.0 9231.5 12303.0 16536.0 11286.0 13867.0 19276.0 21312.0 17568.0 19904.0 15775.0 True False 9099.85711715024 12274.513159394073 15176.473910805908 12116.01008899233 13051.370323570949 18451.61041455068 22415.43107958311 18384.273415137133 17662.201921588097 18501.68773113376 0.4918392986298993 0.6634266742454585 0.8202751084847065 0.6548597222622067 0.7054151228381573 0.9972933649453606 1.2115343965006766 0.9936538591666398 0.9546265280365198 1.0 14.175369259495266 -6.771181064631987 4.189324468678082 1.0475713442555243 0.6709025840311673 0.7772606016758958 0.09780215786335834 0.10187075606166113 4.101816141132517 0.036210393890652164 0.03358634712432301 1.693631549918846e-07 6.771181064631987 -0.376668760224357 RLS(ph)LGAQK ddPTM_PC-9_AZD4547_30min_R2 1 RLSLGAQK 8 1 Q9H788-2;Q9H788 Q9H788-2 SH2D4A SH2 domain-containing protein 4A 1 RLS(1)LGAQK 61.765 0.029611000000000002 36395000.0 46944.0 36673.0 49021.0 61169.0 91635.0 68136.0 52806.0 90494.0 70488.0 71045.0 True False 61871.215504141466 48526.83007039798 48370.949510247614 47067.432101629216 78913.06198523667 63875.44514885821 57505.6317012231 76510.23164524639 74213.851775896 68557.73617441487 0.9024687651111685 0.7078242774373836 0.7055505652518792 0.6865371397603756 1.1510453289250575 0.9317029516020682 0.8387912861493184 1.115997054666448 1.0825014931515773 1.0 16.06503185096212 -6.250609549105362 24.998002986277342 1.0123302833992007 0.7443226380953294 0.6280419498106207 0.10142289771632959 504.7499288996256 1165090.8832037551 0.03131490777902395 0.040019680301346575 5.615526110120446e-07 6.250609549105362 -0.26800764530387133 RLS(ph)LGAQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLSLGAQK 8 1 Q9H788-2;Q9H788 Q9H788-2 SH2D4A SH2 domain-containing protein 4A 1 RLS(1)LGAQK 57.785 0.036777 25827000.0 64939.0 49508.0 74459.0 51589.0 72472.0 58297.0 46155.0 67649.0 36483.0 27964.0 True False 75931.89009628573 54422.82705302648 76234.38494732993 48698.63558379466 58271.631844604985 55239.80269399679 41782.86426673733 65873.28543004031 37016.49485594496 33033.65183709781 2.298622340355718 1.6474965384211009 2.307779512942507 1.4742128973189876 1.7640081736032631 1.6722281558940688 1.2648575601869692 1.9941266486335787 1.120569261869325 1.0 15.011648846479803 -1.522878747398259 0.0733508730355759 0.2729119396565367 5.075387072050799 0.5291307008326918 0.29651000209658096 183.6077715046791 0.9942112331672363 10.83411672328245 90.38378084965939 0.02999999985369917 1.522878747398259 4.802475132394262 RLS(ph)LGQGDSTEAATEER ddPTM_PC-9_AZD4547_30min_R2 6 RLSLGQGDSTEAATEER 17 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RLS(1)LGQGDSTEAATEER;RLS(1)LGQGDSTEAATEER;RLS(1)LGQGDSTEAATEER;RLS(1)LGQGDSTEAATEER;RLS(1)LGQGDSTEAATEER;RLS(1)LGQGDSTEAATEER 122.47 2.6481999999999998e-05 461161300.0 55033.61 60777.91 73088.66 75764.86 66237.83 60336.96 52628.92 72541.4 52764.0 60305.2 True False 72533.15320980042 80423.18083069129 72119.45661311797 58298.442082418354 57041.85065267162 56564.08035295372 57312.79192427252 61331.793465538845 55552.99732015905 58193.93330347429 1.2464040337598226 1.3819856515161841 1.2392951037872586 1.0017958706863663 0.9802027018040748 0.9719927343281458 0.9848585354317481 1.0539207436916318 0.9546183625440288 1.0 15.828581140085186 -5.695651628367499 3.6110032134934493 0.9912865732903515 1.3138406649959147 0.923725569714756 0.03942983946115386 0.05100064420709464 1.3246608104554927 0.01052951477925887 0.018815239933945665 2.0153402175400636e-06 5.695651628367499 0.32255409170556315 RLS(ph)LGQGDSTEAATEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 RLSLGQGDSTEAATEER 17 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RLS(0.929)LGQGDS(0.06)T(0.011)EAAT(0.001)EER;RLS(1)LGQGDSTEAATEER;RLS(1)LGQGDSTEAATEER;RLS(1)LGQGDSTEAATEER;RLS(1)LGQGDSTEAATEER;RLS(1)LGQGDSTEAATEER;RLS(1)LGQGDSTEAATEER 148.64 3.2121999999999995e-05 659035000.0 91125.87999999999 95538.9 114330.38 89751.1 113503.19 89369.5 84019.83 82297.69 82529.8 68298.33 True False 106551.69166583 105023.37059740644 117056.44985958059 84722.63684399206 91263.05470896678 84682.80609398683 76060.86345150786 80137.4628391103 83736.64219395792 80680.27657971738 1.3206659196383639 1.3017229867034044 1.4508682273036233 1.050103450752063 1.1311693337936557 1.0496097644176354 0.9427442080761184 0.993272039169688 1.0378824384819834 1.0 16.299928409205613 -5.775699435602609 23.513614313108548 1.030463958030179 1.3521493691007525 0.8687044445205696 0.058510144207983915 39.091202710317035 64458.02530583991 0.017810123746317706 0.026584458022097558 1.6761024635009212e-06 5.775699435602609 0.32168541107057336 RLS(ph)LGQGDSTEAATEER ddPTM_PC-9_Lapatinib_30min_R1 4 RLSLGQGDSTEAATEER 17 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RLS(1)LGQGDSTEAATEER;RLS(1)LGQGDSTEAATEER;RLS(1)LGQGDSTEAATEER;RLS(1)LGQGDSTEAATEER 168.45 8.6161e-06 492740000.0 45316.100000000006 75041.0 80529.0 48207.5 58791.4 64577.0 55070.0 50291.5 66062.0 58392.6 True False 44669.88410404504 74867.2471750053 73908.2164709296 51752.84036550576 55333.40544033959 61815.19224633944 57921.255140420544 52628.226688147115 58621.401896299925 68485.68310675122 0.652251420700826 1.0931809946073967 1.0791776195869445 0.7556738579191311 0.8079558081371448 0.9026002142664732 0.8457425335180857 0.7684558918119209 0.8559657907613264 1.0 16.063514804561457 -5.773472259328865 24.99852920773132 0.8389140449126968 0.9567011420559317 0.0915178802816281 0.13019624600032292 415.9361201986073 864114.9212711256 0.03594390295261891 0.05377377013955633 1.6847200352605002e-06 5.773472259328865 0.11778709714323488 RLS(ph)LGQGDSTEAATEERGPR ddPTM_PC-9_Lapatinib_30min_R1 1 RLSLGQGDSTEAATEERGPR 20 2 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RLS(0.997)LGQGDS(0.001)T(0.001)EAATEERGPR 42.148999999999994 0.035533999999999996 25232000.0 21579.0 2916.6 5832.2 0.0 2971.5 0.0 2307.7 0.0 6753.8 0.0 True False 21271.279502896054 2909.84679189537 5352.699028943047 0.0 2796.7222121937752 0.0 2427.18141433718 0.0 5993.115923333077 0.0 0.0 RLS(ph)LLQTELEEVR ddPTM_PC-9_AZD4547_30min_R2 1 RLSLLQTELEEVR 13 1 Q9H6N6 Q9H6N6 MYH16 Putative uncharacterized protein MYH16 1 RLS(1)LLQTELEEVR 85.176 0.0037689 6773000.0 7426.7 4772.8 9919.4 7342.1 8132.9 8550.3 3923.0 6628.1 6580.0 6057.3 True False 9788.236115043614 6315.514262809024 9787.862274779174 5649.492279314228 7003.7872190727385 8015.648389343112 4272.139400141998 5603.879443585847 6927.805366663757 5845.235770698631 1.6745665186185825 1.080455008242411 1.6745025622138958 0.966512301802155 1.1982043999288732 1.371313100751977 0.7308754629809201 0.9587088807738654 1.1852054627790891 1.0 12.513045502465664 -4.904889578234654 0.39256106842409644 0.9741991275595832 1.885974450762713 0.35521436227091163 0.2360960320871827 6.176735529295429 0.8103586542133573 0.2001072924090872 2.6445504344747373 1.2448310766995054e-05 4.904889578234654 0.9117753232031298 RLS(ph)LLQTELEEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RLSLLQTELEEVR 13 1 Q9H6N6 Q9H6N6 MYH16 Putative uncharacterized protein MYH16 1 RLS(1)LLQTELEEVR;RLS(1)LLQTELEEVR 118.71 0.00010963 8191500.0 8528.5 7600.3 11016.2 10572.3 11380.900000000001 9273.8 10818.3 10717.7 10216.9 8063.0 True False 9972.206604446837 8354.80755536716 11278.867987171157 9979.968306859064 9150.89434347424 8787.465602408145 9793.512306290648 10436.371731341831 10366.302834024184 9524.758073327119 1.0469774169249235 0.8771674294556355 1.1841631987227268 1.047792314516282 0.9607482177526548 0.9225920002121977 1.028216384174223 1.09570990160554 1.0883534000778146 1.0 13.217466733609907 -7.542393846804595 12.667957792460264 1.0676377171044305 1.0057940537666854 0.0812944114546279 0.08158679584266877 2.3623195558495227 1520.568753752849 0.03926982691349613 0.02278346151505992 2.8681783494657377e-08 7.542393846804595 -0.06184366333774505 RLS(ph)LLQTELEEVR ddPTM_PC-9_Lapatinib_30min_R1 2 RLSLLQTELEEVR 13 1 Q9H6N6 Q9H6N6 MYH16 Putative uncharacterized protein MYH16 1 RLS(0.999)LLQT(0.001)ELEEVR;RLS(1)LLQTELEEVR 105.02 0.00058448 6896800.0 10129.3 9866.4 10176.599999999999 8555.2 11694.2 8948.2 8438.4 7376.2 9808.1 8914.5 True False 9984.854324513884 9843.554956989805 9339.919230812007 9184.377947310577 11006.370147681793 8565.506345273006 8875.29906259169 7718.925180141989 8703.408494128227 10455.359447175399 0.9549986659914763 0.9414841265595246 0.8933140250223787 0.8784373214248327 1.0527012680233825 0.8192455160006047 0.8488755558747839 0.7382744915792752 0.8324351293804179 1.0 13.351955041069791 -6.8335421915890295 24.99999000495182 0.8314769311949495 0.9375638056946853 0.277210781467468 0.07521309687203903 51.94014892424844 18007.70773341697 0.02557844664251176 0.02255807495734383 1.4670935522506543e-07 6.8335421915890295 0.10608687449973586 RLS(ph)LPADIR ddPTM_PC-9_AZD4547_30min_R2 2 RLSLPADIR 9 1 Q00537-2;Q00537;F5H6Z0;F8VQZ9;F8VZY6;E5RGN0;A0A087WZU2;Q00536;Q00536-3;Q00536-2;E5RJM2;E5RIY8;H0YBX5;E5RIU4 Q00537-2;E5RGN0 CDK17;CDK16 Cyclin-dependent kinase 17;Cyclin-dependent kinase 16 1 RLS(1)LPADIR;RLS(1)LPADIR 85.973 0.0055111000000000005 26964000.0 68153.0 65531.0 78836.0 94117.0 88496.0 91860.0 61656.0 92751.0 64774.0 69814.0 True False 89824.23632953646 86712.61422145026 77790.58312947261 72419.77974315488 76209.85795215247 86115.97967849777 67143.26455650145 78418.46415594671 68197.82140125814 67369.83310972789 1.3333005617400924 1.2871133891666027 1.1546797659832708 1.0749585741915368 1.1312163684304588 1.2782572807956536 0.9966369435284571 1.163999679622532 1.0122901935972097 1.0 16.03981510499805 -1.5228787452803376 0.28279002920017343 1.048137678668177 3.2590169880299804 0.5591988638115764 0.07843888008572907 42.34278070528241 0.5981007604048325 0.08739818996028446 46.41101269661909 0.029999999999999995 1.5228787452803376 2.210879309361803 RLS(ph)LPADIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RLSLPADIR 9 1 Q00537-2;Q00537;F5H6Z0;F8VQZ9;F8VZY6;E5RGN0;A0A087WZU2;Q00536;Q00536-3;Q00536-2;E5RJM2;E5RIY8;H0YBX5;E5RIU4 Q00537-2;E5RGN0 CDK17;CDK16 Cyclin-dependent kinase 17;Cyclin-dependent kinase 16 1 RLS(1)LPADIR;RLS(1)LPADIR;RLS(1)LPADIR;RLS(1)LPADIR 82.774 0.0070068 30055100.0 108349.0 104727.0 106242.0 103732.0 134333.0 94642.2 109400.0 82464.0 82825.3 72763.6 True False 126690.34570970388 115123.60444336878 108775.21220502883 97920.23234368164 108011.41296750934 89678.99642392897 99036.8400125893 80299.4073778305 84036.46332242669 85955.06468365937 1.473913680083456 1.3393463767034375 1.2654892716950945 1.139202590377399 1.2566032422292277 1.0433241689012136 1.1521931881160792 0.934202163343796 0.977679019051481 1.0 16.39129502889476 -3.729825971151672 0.2773642610151755 0.9468711060452519 2.288754676858929 0.8466692615344267 0.06494320939936725 5.599688797865748 0.2250633918030719 0.07681861537455785 2.831048021589671 0.00018628334547246555 3.729825971151672 1.341883570813677 RLS(ph)LPADIR ddPTM_PC-9_Lapatinib_30min_R1 2 RLSLPADIR 9 1 Q00537-2;Q00537;F5H6Z0;F8VQZ9;F8VZY6;E5RGN0;A0A087WZU2;Q00536;Q00536-3;Q00536-2;E5RJM2;E5RIY8;H0YBX5;E5RIU4 Q00537-2;E5RGN0 CDK17;CDK16 Cyclin-dependent kinase 17;Cyclin-dependent kinase 16 1 RLS(1)LPADIR;RLS(1)LPADIR 82.85 0.006956100000000001 25981000.0 109747.0 124163.0 140256.0 117403.0 136238.0 161730.0 127065.0 136792.0 141475.0 115719.0 True False 108181.98765486483 123875.50820205208 128724.69308381682 126037.20826492702 128224.74869421362 154813.184911044 133643.8039661801 143147.8557037474 125540.59570220418 135720.87496412484 0.7970917346610138 0.9127225876991741 0.9484516889376279 0.9286501306320232 0.9447680670206946 1.140673348532168 0.9846960093759064 1.0547224643341397 0.9249910578265015 1.0 17.050283110381827 -3.634559942240369 0.5453040379515796 1.0158730314406388 0.17364822284574527 0.5378168856707006 0.058890823254362484 9.969900576906795 0.8657940099934927 0.030934807196551978 7.030435356658761 0.00023197439875151726 3.634559942240369 -0.8422248085948936 RLS(ph)LPGLLS(ph)QVSPR ddPTM_PC-9_AZD4547_30min_R2 2 RLSLPGLLSQVSPR 14 1 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 2 RLS(1)LPGLLS(0.755)QVS(0.245)PR;RLS(1)LPGLLS(0.774)QVS(0.226)PR 111.82 0.00027369 8926500.0 14517.8 12857.300000000001 18414.1 24206.4 22278.3 19217.2 16876.1 20957.8 15495.4 18318.3 True False 19134.15841100087 17013.170786794868 18169.917002440805 18625.988465151924 19185.34259645001 18015.5454460878 18378.040206662336 17719.253572333455 16314.45520951392 17676.98189265658 1.0824335583524942 0.9624477125171762 1.0278857054206183 1.0536860069359228 1.0853290857541715 1.019152791776738 1.0396593897229138 1.0023913403279796 0.9229208531514826 1.0 14.109584354494439 -7.997521841725507 4.3241157723498995 0.960634392800875 1.0364958697608808 0.41004271024621775 0.03699196728628968 0.19593870282208392 8.903551919858595 0.02413561318070254 0.00975745073838097 1.0057224815007487e-08 7.997521841725507 0.07586147696000578 RLS(ph)LPGLLS(ph)QVSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLSLPGLLSQVSPR 14 1 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 2 RLS(1)LPGLLS(0.901)QVS(0.099)PR 96.56200000000001 0.0022025 946000.0 3412.9 2272.6 3570.2 3141.5 2977.7 2673.5 1973.8 2341.9 3249.9 2156.5 True False 3990.636562152383 2498.2087089098336 3655.3271080588975 2965.4919398804195 2394.2410605983036 2533.2969535722314 1786.8273749254931 2280.4276064481587 3297.42363929325 2547.4563791553937 1.5665181138353677 0.9806679044051431 1.4348929143472977 1.1640992026970938 0.9398555673766282 0.994441739729472 0.7014162792133515 0.8951782747323163 1.294398469891173 1.0 11.314841727573299 -6.103515964519059 3.5656422104183236 0.9535515632290793 1.2946606151027862 0.3980378269199698 0.19527395170369571 0.2545399331299424 5.959573348498174 0.05839130422067407 0.07908473660268897 7.879234671173786e-07 6.103515964519059 0.3411090518737069 RLS(ph)LPGLLS(ph)QVSPR ddPTM_PC-9_Lapatinib_30min_R1 1 RLSLPGLLSQVSPR 14 1 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 2 RLS(1)LPGLLS(0.939)QVS(0.061)PR 69.07 0.023056 4334400.0 21526.0 16025.0 15840.0 16721.0 19731.0 18659.0 16113.0 15929.0 22242.0 13221.0 True False 21219.035292615063 15987.895097073057 14537.696344168215 17950.718119620822 18570.461372638536 17860.998066253433 16947.25229848549 16669.119491673453 19736.871741356616 15506.232234124858 1.3684198051618195 1.0310625338041948 0.9375389278753888 1.1576453808112288 1.1976127464265736 1.1518593167298499 1.092931670479522 1.0749948304649666 1.272834783031387 1.0 13.920560556736586 -4.751400468973995 24.984210414407578 1.1050632332574852 1.3684203456998782 0.42250568796342314 0.09343315685734024 434.6021489811226 1081536.0040425465 0.02398315971279017 0.3195102692773997 1.772554230186392e-05 4.751400468973995 0.263357112442393 RLS(ph)LPGLLSQVS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 RLSLPGLLSQVSPR 14 1 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 2 RLS(1)LPGLLS(0.036)QVS(0.964)PR 85.7 0.0051244 3232000.0 17075.0 14646.0 17960.0 27511.0 22828.0 17323.0 18849.0 17930.0 21252.0 18237.0 True False 22504.494817936604 19380.033081859903 17721.838665144474 21168.763990712963 19658.72623996269 16239.79007152858 20526.52448464861 15159.330490411157 22375.3373331821 17598.52818091079 1.2787714169385676 1.1012303348686578 1.0070068634698348 1.2028712727053406 1.1170664977135192 0.9227925144981135 1.1663773398342385 0.8613976313572947 1.271432309745808 1.0 14.103167156429564 -6.545894045206985 24.98895349388147 1.0407573875374005 1.1373634556814716 0.12988060253889488 0.12622361876815325 497.60924846181064 540277.078477288 0.03923463603108712 0.03923661486319303 2.845155155076378e-07 6.545894045206985 0.09660606814407102 RLS(ph)LPGLLSQVS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RLSLPGLLSQVSPR 14 1 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 2 RLS(1)LPGLLS(0.412)QVS(0.588)PR;RLS(1)LPGLLS(0.305)QVS(0.695)PR 98.887 0.0017672999999999999 8976100.0 19739.2 22833.9 22118.6 26216.8 24761.8 23018.8 22102.8 20788.8 20574.1 19874.9 True False 23080.656693028905 25100.698688012068 22645.991309257617 24747.957692012387 19909.903044068604 21811.653605718533 20009.06277358558 20243.116027554326 20874.957290126848 23478.06204037818 0.9830733326002032 1.069112886951369 0.9645596502092232 1.0540886061826658 0.8480215705123803 0.9290227433680976 0.8522450762406828 0.8622140955560851 0.889126080944226 1.0 14.519025707924007 -6.260154716158307 24.999983028038404 0.8892685295022881 1.0175839998893723 0.5755604327087618 0.05063225511449382 74.55234338622567 1450811.6537314504 0.014217163896483575 0.01735873453756021 5.493451363716489e-07 6.260154716158307 0.12831547038708424 RLS(ph)LPGLLSQVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 RLSLPGLLSQVSPR 14 1 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 2 RLS(1)LPGLLS(0.138)QVS(0.862)PR 103.31 0.00093988 4100700.0 5596.5 5679.3 6441.2 4382.3 3989.1 3591.4 4450.0 3944.8 4977.4 2336.2 True False 5516.6928837275955 5666.149929785154 5911.629399751031 4704.588960924252 3754.4689808723506 3437.804193962301 4680.399225982774 4128.089809200421 4416.792797654369 2740.0090572091717 2.0133849080581534 2.0679310949272534 2.1575218462132764 1.7169975947875507 1.370239624206372 1.2546689161180606 1.7081692535534831 1.5065971400127687 1.611962845901349 1.0 11.419964946741743 -1.5228787452816048 0.1519324619566869 1.0306861173866446 5.282848509372096 0.6603744701343719 0.20607249203079622 46.23748775323082 0.4607614614953887 0.7892422700963853 43.44162069365478 0.02999999999991246 1.5228787452816048 4.252162391985451 RLS(ph)LPGLLSQVSPR ddPTM_PC-9_AZD4547_30min_R2 2 RLSLPGLLSQVSPR 14 1 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 1 RLS(1)LPGLLSQVSPR;RLS(1)LPGLLSQVSPR 124.99 1.6689000000000002e-05 3191500.0 5380.0 4189.1 6603.4 7619.1 7239.9 5000.6 3238.0 5761.2 4806.6 3554.1 True False 7090.728089048255 5543.144652684646 6515.83460141509 5862.634208921568 6234.764854770713 4687.911691490264 3526.1757271628317 4870.9389192056215 5060.667063131614 3429.6720407838457 2.067465345003565 1.61623169410034 1.8998418869012057 1.7093862442840666 1.8178895184817054 1.366868795541993 1.0281378759343212 1.4202346058990458 1.4755542229556757 1.0 11.743854911277063 -6.818107506072765 4.29087734918768 1.2582851219047 1.8111209674376076 0.7170177979476294 0.17814771256167564 0.12080475464610972 4.523088458095288 0.06247407453496398 0.0561450062627783 1.5201711771209494e-07 6.818107506072765 0.5528358455329077 RLS(ph)LPGLLSQVSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RLSLPGLLSQVSPR 14 1 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 1 RLS(1)LPGLLSQVSPR;RLS(1)LPGLLSQVSPR 133.94 7.4117e-06 2968300.0 6279.8 6723.6 4961.1 5916.4 5905.0 5785.1 3964.5 5243.4 3158.2 4147.9 True False 7342.846108296326 7391.074573275611 5079.391439076526 5584.923289227602 4747.957639397178 5481.719171913489 3588.953859505585 5105.7663058415255 3204.3827002726057 4899.8814352416675 1.4985762829859512 1.5084190650239837 1.0366355811272818 1.1398078429120495 0.9689943934659725 1.1187452685052826 0.7324572863523939 1.0420183372436447 0.653971477192399 1.0 12.258531124735162 -4.651717563608508 0.5168946099989211 0.8707385311556355 2.143147840894303 0.7003760260614255 0.1434876244132898 2.5605602278443502 0.4756422420191518 0.08131836283979652 2.036841678596897 2.2298848473669374e-05 4.651717563608508 1.2724093097386675 RLS(ph)LPGLLSQVSPR ddPTM_PC-9_Lapatinib_30min_R1 1 RLSLPGLLSQVSPR 14 1 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 1 RLS(1)LPGLLSQVSPR 84.895 0.018788 0.0 2938.5 3044.0 2893.2 1129.0 2139.4 2707.5 4056.1 2755.6 1034.1 2387.6 True False 2896.596451145099 3036.951805022803 2655.3322640749657 1212.030426233594 2013.5646982222333 2591.7065364907653 4266.105011350275 2883.6352358123795 917.6287684442447 2800.2934787229797 1.034390314141658 1.0845119727978465 0.9482335634641692 0.4328226435703151 0.7190548824691336 0.9255124708116892 1.5234492540745233 1.0297617937986294 0.32769021369242757 1.0 11.451362318300434 -6.999185217876105 24.998652514716795 1.0086733616258143 0.8383587636244867 0.02863664533950938 0.3192236551292471 99.09701646529032 3040310.978890374 0.12091704468966293 0.10573951777144144 1.00187786615892e-07 6.999185217876105 -0.17031459800132764 RLS(ph)LPMDIR ddPTM_PC-9_AZD4547_30min_R2 1 RLSLPMDIR 9 1 Q07002;Q07002-3;A0A0A0MSJ6;D6R9B0;D6RA44;D6RGH0 Q07002 CDK18 Cyclin-dependent kinase 18 1 RLS(1)LPMDIR 82.36200000000001 0.0072824 3358300.0 31121.0 25312.0 37910.0 58408.0 50177.0 41085.0 35381.0 43243.0 36019.0 34878.0 True False 41016.830642987115 33493.60899686181 37407.28863004605 44942.93799460444 43210.78966806586 38515.94845516089 38529.84045792094 36560.787975284424 37922.89080575408 33656.93183603697 1.2186740860041732 0.9951474234202093 1.1114289565156832 1.3353248660201218 1.283860034496651 1.1443689710872962 1.1447817241815985 1.086278100255658 1.1267483022665032 1.0 15.038616046214807 -8.420612045553236 0.8676244426372246 1.0074872478511785 1.178284859897619 0.26137688811312854 0.08985976686668601 0.9474147579048047 1.586067940510906 0.0952519720724294 0.03426431008163215 3.796539777271301e-09 8.420612045553236 0.1707976120464405 RLS(ph)LPSSK ddPTM_PC-9_AZD4547_30min_R2 2 RLSLPSSK 8 1 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3 C9JWC4 HJURP Holliday junction recognition protein 1 RLS(0.988)LPS(0.007)S(0.005)K;RLS(0.974)LPS(0.016)S(0.01)K 58.511 0.035469 37789000.0 108612.0 96677.0 107432.0 175074.0 164799.0 119143.0 111976.0 150111.0 111695.0 118808.0 True False 143148.3567300571 127925.94962822409 106007.38148517825 134713.3941663366 141919.50348780502 111692.9693755196 121941.64707374474 126914.79415761883 117598.96967013812 114648.56808234051 1.248583904050577 1.1158093970815908 0.9246289182525492 1.1750115716193292 1.2378654688986481 0.9742203609145977 1.063612473434176 1.106989788712134 1.0257343082181247 1.0 16.80685881074752 -6.7791217831689075 24.999528474573594 1.0426420930780977 1.1289526930036164 0.2501489164923141 0.09032284942024976 468.2714639899248 662041.7038520599 0.03368874807480164 0.02977156125653461 1.6629462680601984e-07 6.7791217831689075 0.0863105999255187 RLS(ph)LPSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLSLPSSK 8 1 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3 C9JWC4 HJURP Holliday junction recognition protein 1 RLS(0.996)LPS(0.003)S(0.001)K 62.799 0.027747000000000004 10863000.0 82834.0 93465.0 94254.0 104400.0 108710.0 81691.0 88909.0 102350.0 75761.0 69327.0 True False 96856.16015392501 102743.58751133374 96501.37282028545 98550.80646936658 87409.0558812648 77406.98015121349 80486.89587458236 99663.42094878916 76868.86129926943 81895.43630777013 1.1826808003065177 1.2545703661094674 1.1783486012288273 1.2033736055694744 1.0673251138534021 0.9451928415194146 0.9828007457229442 1.2169593989858656 0.938622037623557 1.0 16.32149543825829 -6.321949416617167 3.7535519339759573 1.0264175520347028 1.2078646290287407 0.5792765580884249 0.07562973066938088 0.18059603602267027 5.129552747446222 0.024356435618132152 0.02861288712150147 4.7648648116586133e-07 6.321949416617167 0.18144707699403795 RLS(ph)LQPR ddPTM_PC-9_AZD4547_30min_R2 1 RLSLQPR 7 1 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 RLS(1)LQPR 71.34899999999999 0.01909 8055400.0 3216.3 2934.9 4894.2 6122.6 6126.0 4377.8 2451.8 6665.8 4543.8 5155.6 True False 4239.016496804069 3883.549029902407 4829.29971018653 4711.129163227048 5275.510642457131 4104.055473944339 2670.005450234042 5635.753774845659 4783.97599164845 4975.104013242509 0.8520458035693013 0.7805965502561052 0.9706932151231646 0.9469408379577945 1.0603819796360063 0.8249185269333763 0.5366732922823606 1.1327911456413096 0.9615831104062703 1.0 12.280510972694357 RLS(ph)LQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLSLQPR 7 1 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 RLS(1)LQPR 63.184 0.029316000000000002 5687200.0 9850.6 8646.5 8096.1 9363.3 7726.3 6873.9 3908.5 6991.2 4328.4 3074.6 True False 11518.11202178156 9504.867377272232 8289.14172863023 8838.70465722818 6212.386978708625 6513.420583190634 3538.2585849104726 6807.688407788701 4391.694661471707 3632.0006414797936 3.1712857895004976 2.616978441226168 2.282252275498764 2.433563627793581 1.7104586678094582 1.7933423548451954 0.974189966956854 1.8743632173520295 1.2091668187818354 1.0 11.826548742098083 -2.489818241969582 0.22681004886839892 0.958135843944053 9.291930857865305 0.853088941384025 0.26424588032580765 11.631341454768423 0.22126902849756577 0.3965445968379443 32.717117618116646 0.003237291135322209 2.489818241969582 8.333795013921252 up RLS(ph)LQPR ddPTM_PC-9_Lapatinib_30min_R1 2 RLSLQPR 7 1 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 RLS(1)LQPR;RLS(1)LQPR 82.749 0.010097 13783200.0 39855.0 28951.0 28974.0 36872.0 20124.5 13536.3 16847.7 14886.800000000001 25552.0 29154.0 True False 39286.660391488105 28883.96573824414 26591.869562874374 39583.68988138623 18940.816476289292 12957.384003656485 17719.991469570785 15578.495074935303 22674.0646855114 34193.23005473686 1.1489601985129112 0.8447276168997899 0.7776939914803559 1.157646990881536 0.5539346954344075 0.37894589025120407 0.5182309902049163 0.4556017389991263 0.6631156123365513 1.0 15.061423092576435 -6.2813655817664005 23.69950894333245 0.5531131917177332 0.957821979351688 0.480950890759709 0.19353781064088044 331.80636485032693 394637.2510260511 0.0577371636918717 0.06557390220956275 5.231598640329699e-07 6.2813655817664005 0.4047087876339548 RLS(ph)LTLR ddPTM_PC-9_AZD4547_30min_R2 1 RLSLTLR 7 1 Q00537-2;Q00537;F8VQZ9;F8VZY6;F8VUX2;F8W1S5 Q00537-2 CDK17 Cyclin-dependent kinase 17 1 RLS(0.918)LT(0.082)LR 70.399 0.02021 8342300.0 16123.0 11220.0 13130.0 21058.0 25116.0 16345.0 16500.0 25162.0 19981.0 19861.0 True False 21249.77862076672 14846.645580941433 12955.88762101041 16203.403442856803 21629.076933717475 15322.944566133734 17968.468035264585 21273.79106523846 21037.15486798004 19165.672435217908 1.108741615646063 0.7746477787891208 0.6759944199611437 0.8454388176374243 1.1285321194352114 0.7994994497546059 0.9375339214420988 1.1099945038268928 1.0976476269793272 1.0 14.226236996103507 -7.633493831264609 4.607922889041394 1.0766006425235806 0.8818419940429199 0.261048400499744 0.13496045481508778 0.2895834380706215 10.363125203805467 0.06976703082226801 0.03870979799373672 2.3254455163556358e-08 7.633493831264609 -0.1947586484806607 RLS(ph)LTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLSLTLR 7 1 Q00537-2;Q00537;F8VQZ9;F8VZY6;F8VUX2;F8W1S5 Q00537-2 CDK17 Cyclin-dependent kinase 17 1 RLS(0.995)LT(0.005)LR 70.399 0.02021 4406600.0 8368.7 7215.7 8891.7 8667.7 10885.0 5808.2 7091.1 8758.1 5485.6 4602.7 True False 9785.355620640708 7932.027009100013 9103.711849960036 8182.076870062554 8752.1623886263 5503.607767248265 6419.37967288184 8528.209154973996 5565.816522264394 5437.133075046848 1.7997270777773624 1.4588620325485906 1.6743588439540993 1.504851317252715 1.6097017063631258 1.0122260557694451 1.1806552431727135 1.568512125280383 1.0236675184221857 1.0 12.408630423513694 -6.745694824686076 24.85672427903281 1.194021903108437 1.5989209661492347 0.6157994122587679 0.177406970261712 167.66635672520454 264702.8122901289 0.05766654237132753 0.05747552779955784 1.7959952152272243e-07 6.745694824686076 0.4048990630407978 RLS(ph)LTMGGVQAR ddPTM_PC-9_AZD4547_30min_R2 1 RLSLTMGGVQAR 12 1 O75815;O75815-3 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 RLS(0.99)LT(0.01)MGGVQAR 84.734 0.014761000000000002 17155000.0 24317.0 25086.0 30163.0 41692.0 59229.0 34195.0 23409.0 41226.0 29572.0 37064.0 True False 32049.300174978893 33194.55891653268 29763.01891184592 32080.553534978924 51006.07571695943 32056.781244352587 25492.355650758098 34855.46897923537 31135.115547565467 35766.4006414036 0.8960728393194325 0.9280933591653133 0.8321502409552475 0.8969466583070734 1.4260891451826496 0.8962820040449719 0.7127459065939068 0.9745310781674317 0.8705129671763252 1.0 15.126317319295037 -10.592615648692131 11.508155195038398 0.9999739885373398 0.9402091624198328 0.011040731891510225 0.17647300709387248 0.0 0.0 0.1787682825084856 0.043357677134867316 2.554961447346233e-11 10.592615648692131 -0.059764826117507 RLS(ph)LTMGGVQAR ddPTM_PC-9_Lapatinib_30min_R1 2 RLSLTMGGVQAR 12 1 O75815;O75815-3 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 RLS(0.781)LT(0.219)MGGVQAR;RLS(0.63)LT(0.37)MGGVQAR 74.89 0.0093254 26762000.0 67101.0 49665.0 59080.0 68172.0 43213.0 56747.0 57999.0 45658.0 47681.0 46553.0 True False 66144.12743518363 49550.0037439085 54222.67045539506 73185.59629512543 40671.29630002681 54320.06309371797 61001.9044287135 47779.437362723795 42310.66367681077 54599.62402202668 1.2114392474296096 0.9075154752699204 0.9930960409822686 1.3404047666262457 0.7449006660488929 0.9948798012199511 1.1172586903547908 0.8750872962687166 0.7749259163349134 1.0 15.73660339619961 -6.885784881008041 0.7039841053812578 0.9001602615616799 1.0741923115143623 0.13707903089341367 0.1646423840128033 1.6260613550311662 1.7329689302360938 0.12875892499996675 0.11571695810496947 1.3008137502753555e-07 6.885784881008041 0.1740320499526824 RLS(ph)MEIEK ddPTM_PC-9_AZD4547_30min_R2 1 RLSMEIEK 8 1 A0A5K1VW66;P35240-4;P35240-6;P35240-5;P35240-3;P35240;P35240-2;P35240-8 A0A5K1VW66 NF2 Merlin 1 RLS(1)MEIEK 65.347 0.019369 13393000.0 55092.0 56851.0 113680.0 135590.0 110820.0 95731.0 74231.0 182860.0 92007.0 124930.0 True False 72610.11001521311 75226.97396810162 112172.52892280747 104331.82034461747 95434.55589244195 89744.92543655836 80837.41519549846 154603.18870477338 96870.30218398679 120556.23872573246 0.6022924303436703 0.6239990129357328 0.9304581007873174 0.8654203336749264 0.7916185582859566 0.7444237343927893 0.67053697137487 1.282415496194256 0.8035279070407 1.0 16.87934678606397 -3.3719680606298685 0.20824882387628987 1.0205674929305442 9.18918057078245e-13 0.29615099017941116 0.16227205007746312 33.26514261652547 0.7983188696105191 0.30990207252949814 9.616861223816112 0.00042465079294114053 3.3719680606298685 -1.0205674929296253 RLS(ph)MEIEK ddPTM_PC-9_Lapatinib_30min_R1 4 RLSMEIEK 8 1 A0A5K1VW66;P35240-4;P35240-6;P35240-5;P35240-3;P35240;P35240-2;P35240-8 A0A5K1VW66 NF2 Merlin 1 RLS(1)MEIEK;RLS(1)MEIEK;RLS(1)MEIEK;RLS(1)MEIEK 92.611 0.0035963 30887900.0 241999.0 187420.0 198317.0 171911.0 193370.0 195647.0 158954.0 168636.0 188688.0 149770.0 True False 238548.0498828187 186986.04050505062 182012.14178575782 184553.90841828482 181996.35678004706 187279.6338854324 167183.8603521048 176471.44419598504 167435.9704672735 175657.5449440191 1.3580290556767283 1.0644919383601874 1.0361760540588445 1.0506460652009053 1.0360861916751034 1.0661633347153816 0.951760201392916 1.0046334431704902 0.9531954378653889 1.0 17.422406019796107 -2.2169624285248193 1.194323570348848 1.0093724067350185 199.99999997384492 0.8891626393440395 0.036359296389769084 266.86011714072754 0.9033610369378718 0.011316919826383949 144871.4012065157 0.006067888215403586 2.2169624285248193 198.9906275671099 RLS(ph)MENEELLWK ddPTM_PC-9_Lapatinib_30min_R1 1 RLSMENEELLWK 12 1 Q9ULD2-7;Q9ULD2-4;Q9ULD2-3;Q9ULD2-6;Q9ULD2-2;Q9ULD2 Q9ULD2-7 MTUS1 Microtubule-associated tumor suppressor 1 1 RLS(1)MENEELLWK 67.646 0.023257 0.0 19134.0 19216.0 13105.0 13718.0 12659.0 12476.0 10911.0 10530.0 14100.0 10953.0 True False 18861.145651254148 19171.50653262753 12027.557486762913 14726.86748190649 11914.422508551575 11942.430562976462 11475.918192066983 11019.262241654937 12511.909520417612 12846.211456044897 1.4682263105967224 1.492386031338929 0.9362727312964508 1.1463977167351262 0.9274658563202414 0.9296461142523734 0.89333094284906 0.8577830342711451 0.9739766127335561 1.0 13.649055328894034 -5.260977517871724 24.99756009859244 0.9553300863416342 1.4803062214335792 0.88930539250621 0.07368878797121504 11.992228988860223 649013.6137860747 0.020490582883181865 0.04791216211216691 5.4830534831651435e-06 5.260977517871724 0.524976135091945 RLS(ph)MSEVKDDNSATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLSMSEVKDDNSATK 15 2 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;Q8TDM6-5 Q8TDM6-4 DLG5 Disks large homolog 5 1 RLS(0.74)MS(0.26)EVKDDNSATK 65.374 0.03069 12771000.0 38118.0 29104.0 24678.0 30648.0 31830.0 28408.0 26312.0 34054.0 23905.0 23099.0 True False 44570.624535182586 31993.25277836476 25266.417111836177 28930.89192215662 25593.139993566856 26918.234470574127 23819.53687761659 33160.1185831955 24254.56540118315 27286.665848416607 1.6334214221254493 1.1724866994045469 0.9259620523883954 1.0602574929041917 0.9379357718433737 0.9864977502238933 0.872936877298946 1.2152499234390601 0.8888797750491967 1.0 14.735908502346941 -4.790414413669992 2.57372089000522 0.9909139252408714 1.7623908954521335 0.813138742959842 0.09379804630502224 0.18668868656355908 1.6270547011729262 0.022995644305822023 0.31622711379353785 1.6202632674134485e-05 4.790414413669992 0.771476970211262 RLS(ph)MSEVKDDNSATK ddPTM_PC-9_Lapatinib_30min_R1 1 RLSMSEVKDDNSATK 15 2 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;Q8TDM6-5 Q8TDM6-4 DLG5 Disks large homolog 5 1 RLS(0.817)MS(0.183)EVKDDNSATK 65.374 0.03069 9211900.0 43590.0 39542.0 31665.0 30965.0 33571.0 29714.0 27476.0 25729.0 34186.0 36466.0 True False 42968.398606573 39450.44292845322 29061.625930434748 33242.2693962119 31596.419783125428 28443.201486717124 28898.5728388995 26924.463268332376 30335.61268546072 42769.09951210927 1.0046598852147284 0.9224052733979954 0.6795005333747205 0.7772496913758957 0.738767478005458 0.6650409246672113 0.6756881292466167 0.6295307494306542 0.7092880848910966 1.0 15.38428121166221 -5.135369700161716 3.7155170991310555 0.718237958421979 0.9902662136758602 0.46111535489190114 0.09922313155041004 0.17977270919570043 4.3198436994467535 0.024286598035934026 0.07796292597486654 7.3220096991710465e-06 5.135369700161716 0.2720282552538812 RLS(ph)NLPGYLQK ddPTM_PC-9_AZD4547_30min_R2 2 RLSNLPGYLQK 11 1 Q6ZN28 Q6ZN28 MACC1 Metastasis-associated in colon cancer protein 1 1 RLS(0.999)NLPGY(0.001)LQK;RLS(1)NLPGYLQK 94.45 0.0030384 15820000.0 167698.0 189819.0 237280.0 316490.0 295540.0 266790.0 215280.0 248010.0 225298.0 234120.0 True False 221022.47566491007 251174.27963714107 234133.51216400237 243528.12022175646 254509.37239173654 250107.57912504292 234439.50294737905 209685.75320283676 237206.7923250172 225923.53006058186 0.9783065783614591 1.111766798127615 1.0363396504171964 1.0779227827949303 1.126528840636871 1.1070452867745828 1.0376940502147503 0.928127110737908 1.0499428380098774 1.0 17.78547501047931 -7.526948508953889 24.90083337407393 0.9900030820102461 1.0754594705810596 0.35520046862491716 0.048394656336146286 116.39047386336944 712116.0862538908 0.021945498859107952 0.012738118086917624 2.972018380824363e-08 7.526948508953889 0.0854563885708135 RLS(ph)NLPGYLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RLSNLPGYLQK 11 1 Q6ZN28 Q6ZN28 MACC1 Metastasis-associated in colon cancer protein 1 1 RLS(1)NLPGYLQK;RLS(1)NLPGYLQK 105.14 0.00119 13869900.0 158653.0 132230.0 159854.0 183987.0 203790.0 181645.0 190144.0 162013.0 161895.0 129889.0 True False 185509.81936041586 145356.92052237425 163665.5256096711 173678.80488390246 163858.81241875584 172119.216432253 172132.1837966528 157760.33041696253 164262.4080997508 153436.847499242 1.2090304407572785 0.9473403741763682 1.0666637660844775 1.1319237048633997 1.0679234818061896 1.1217593377177753 1.1218438504317103 1.0281776052375027 1.0705538518090467 1.0 17.227285458717198 -8.570910896150139 1.1566003989291531 1.0025418733968945 1.0875260214222837 0.147473172096537 0.06516844592046431 1.1434494867282994 3.3229401126894698 0.06041121349114412 0.019029788990849176 2.685895452143378e-09 8.570910896150139 0.08498414802538923 RLS(ph)NLPGYLQK ddPTM_PC-9_Lapatinib_30min_R1 1 RLSNLPGYLQK 11 1 Q6ZN28 Q6ZN28 MACC1 Metastasis-associated in colon cancer protein 1 1 RLS(1)NLPGYLQK 101.75 0.0016515999999999998 7147200.0 114730.0 83669.0 82186.0 67853.0 79186.0 91652.0 76248.0 79748.0 90357.0 57884.0 True False 113093.92916109468 83475.2695711081 75428.98432713457 72843.13597097257 74528.43516566603 87732.25761124716 80195.7483556706 83453.38321438732 80180.04315860804 67889.17227441813 1.6658610699207261 1.2295814895737518 1.1110605977377277 1.072971337410475 1.0977956081775604 1.2922864526410829 1.181274504739982 1.2292591059595825 1.1810431689240277 1.0 16.050893875202824 -4.764340307652957 3.617516565956484 1.156454404157057 1.7337503637815534 0.7946949643341261 0.0787548518366158 0.13169195244830018 2.8733650003137607 0.020439356214998514 0.21258230112863638 1.72051986907235e-05 4.764340307652957 0.5772959596244964 RLS(ph)NLPTVDPIAVCHELYNTIR ddPTM_PC-9_AZD4547_30min_R2 4 RLSNLPTVDPIAVCHELYNTIR 22 1 Q86U86-8;Q86U86;E7EVG2;Q86U86-5;Q86U86-4;Q86U86-7;Q86U86-9;Q86U86-2;Q86U86-6;Q86U86-3;C9JCJ2;C9J053;C9JQF1;C9JPI5 Q86U86-8 PBRM1 Protein polybromo-1 1 RLS(0.898)NLPT(0.102)VDPIAVCHELYNTIR;RLS(0.938)NLPT(0.062)VDPIAVCHELYNTIR;RLS(0.633)NLPT(0.367)VDPIAVCHELYNTIR;RLS(0.977)NLPT(0.023)VDPIAVCHELYNTIR 135.21 1.0853e-05 28853500.0 47361.4 41687.7 59256.0 70506.4 68739.1 56077.0 46158.4 59882.1 42324.49999999999 49945.700000000004 True False 62421.34002168219 55162.433777594655 58470.22672281741 54252.23879302108 59195.86248823459 52570.49632518088 50266.408179330676 50628.69739876463 44561.68666282072 48197.11624528792 1.2951260341802073 1.144517308812801 1.2131478245554548 1.125632465579829 1.2282034092448837 1.0907394553988596 1.0429339366179415 1.0504507601886748 0.9245716369426433 1.0 15.556659208513343 -7.234503427270421 0.9233585675142703 0.9707494845977707 1.2049378065659009 0.7641262327627153 0.052126069966406334 0.2736627738703864 0.45673415250731464 0.03745337247507456 0.02211601869445499 5.8276917580761155e-08 7.234503427270421 0.23418832196813022 RLS(ph)NLPTVDPIAVCHELYNTIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RLSNLPTVDPIAVCHELYNTIR 22 1 Q86U86-8;Q86U86;E7EVG2;Q86U86-5;Q86U86-4;Q86U86-7;Q86U86-9;Q86U86-2;Q86U86-6;Q86U86-3;C9JCJ2;C9J053;C9JQF1;C9JPI5 Q86U86-8 PBRM1 Protein polybromo-1 1 RLS(0.991)NLPT(0.009)VDPIAVCHELYNTIR;RLS(0.999)NLPT(0.001)VDPIAVCHELYNTIR 131.7 3.1954e-07 5659900.0 11631.6 12271.400000000001 16284.8 14495.3 16346.0 20299.7 27929.0 22316.5 22663.0 18122.8 True False 13600.600145428134 13489.62349314271 16673.091392447917 13683.175335396669 13143.118640742816 19235.147996420525 25283.36293155036 21730.715521286274 22994.40350081631 21408.320179994127 0.6352950643057818 0.6301112548638279 0.7788136225666488 0.6391522184063496 0.6139257321564602 0.8984893646347643 1.1810063899911878 1.0150593478881833 1.074087238395489 1.0 14.38588397755829 -6.949978307879627 3.9210656007476414 1.0675963646912956 0.6647185920545383 0.9024464005709502 0.06335603057272626 0.06339703192142619 2.0435787267026546 0.023676800190336265 0.020194433462149653 1.1220744982266182e-07 6.949978307879627 -0.4028777726367573 RLS(ph)NLPTVDPIAVCHELYNTIR ddPTM_PC-9_Lapatinib_30min_R1 2 RLSNLPTVDPIAVCHELYNTIR 22 1 Q86U86-8;Q86U86;E7EVG2;Q86U86-5;Q86U86-4;Q86U86-7;Q86U86-9;Q86U86-2;Q86U86-6;Q86U86-3;C9JCJ2;C9J053;C9JQF1;C9JPI5 Q86U86-8 PBRM1 Protein polybromo-1 1 RLS(0.969)NLPT(0.031)VDPIAVCHELYNTIR;RLS(0.973)NLPT(0.027)VDPIAVCHELYNTIR 131.3 6.610800000000001e-07 17580700.0 16255.0 18583.9 23632.4 10898.7 29182.0 34384.0 40552.0 32812.0 36526.0 29621.0 True False 16023.200719198085 18540.87012134141 21689.435295702075 11700.226754997404 27465.57213401943 32913.47647301883 42651.58413754011 34336.565306095166 32412.057244168314 34740.95038249848 0.46121941232989777 0.5336892030070018 0.6243189969445571 0.3367848785418274 0.7905820604106392 0.9473971238737247 1.2277034355118501 0.9883599880846371 0.9329640348727076 1.0 15.084349600879364 -6.56927413423393 2.771755079880139 1.035065333790495 0.5026544478698199 0.8516682860386928 0.10381361601516793 0.09813024651772956 1.5328868840068655 0.03672317774320251 0.03808245511401648 2.6960371096974673e-07 6.56927413423393 -0.532410885920675 RLS(ph)NVSLTGVSTIR ddPTM_PC-9_AZD4547_30min_R2 1 RLSNVSLTGVSTIR 14 1 Q15139;F8WBA3;A0A494C0Q1 Q15139 PRKD1 Serine/threonine-protein kinase D1;Serine/threonine-protein kinase 1 RLS(0.989)NVS(0.011)LT(0.001)GVSTIR 61.957 0.022959999999999998 5071700.0 25341.0 19363.0 17678.0 23264.0 21430.0 20028.0 15342.0 19275.0 19912.0 21557.0 True False 33398.91087445573 25621.711085897427 17443.5781694 17900.844225217057 18454.81440872614 18775.645993914124 16707.40827860783 16296.491645436417 20964.507668846316 20802.295991440136 1.605539642748999 1.231677075282479 0.8385410041553969 0.8605225227341738 0.8871527650755496 0.902575658073515 0.8031521273172298 0.7833987004195212 1.007797777585365 1.0 14.344455149870571 -4.948412976741564 2.290588443283175 0.8733041741886747 1.665446158276099 0.905744640988397 0.07350274310846758 0.10868877549334206 0.8918349122544177 0.01924813559105746 0.15237056127454773 1.1261260976991492e-05 4.948412976741564 0.7921419840874244 RLS(ph)NVSLTGVSTIR ddPTM_PC-9_Lapatinib_30min_R1 2 RLSNVSLTGVSTIR 14 1 Q15139;F8WBA3;A0A494C0Q1 Q15139 PRKD1 Serine/threonine-protein kinase D1;Serine/threonine-protein kinase 1 RLS(0.999)NVS(0.001)LTGVSTIR;RLS(0.994)NVS(0.004)LT(0.001)GVSTIR 97.352 0.0012482 8213600.0 47424.0 43483.0 42702.0 36255.0 42319.0 40445.0 44624.0 37842.0 40342.0 31240.0 True False 46747.72506350352 43382.31778508756 39191.20639448679 38921.313643134585 39829.87962235516 38715.261631899884 46934.41237309109 39600.27746901295 35798.25913990689 36639.79237531657 1.2758730885985166 1.1840219327856585 1.0696350566901427 1.0622689464079778 1.0870661933441437 1.0566452242775677 1.2809682951344938 1.0807997235183788 0.977032259713988 1.0 15.161123707767334 -4.988147806460131 2.6709361542607515 1.0861893373026048 1.279684590640365 0.40647476765666735 0.07706779544118096 0.3478881197319327 4.396919621701966 0.020941283201705 0.12272736231845811 1.0276664857236436e-05 4.988147806460131 0.1934952533377603 RLS(ph)PAER ddPTM_PC-9_Lapatinib_30min_R1 1 RLSPAER 7 1 P41212 P41212 ETV6 Transcription factor ETV6 1 RLS(1)PAER 55.083999999999996 0.044323 66381000.0 13154.0 8366.9 12516.0 9069.2 8426.5 7999.2 8412.0 8164.8 10145.0 7709.2 True False 12966.421547851836 8347.526957110804 11486.982793157156 9736.179221964308 7930.869837136412 7657.0928630459575 8847.53219976789 8544.166415067828 9002.363268413943 9041.724948136702 1.4340650287668757 0.9232228369024921 1.2704415207326527 1.0768055075564666 0.8771412404853995 0.8468619546565519 0.9785225994505804 0.9449708395330684 0.9956466625617858 1.0 13.142382315790034 -6.038919586692598 4.658751422174021 0.936475831459062 1.1810306745606276 0.47315207002741577 0.1264115071501355 0.1834168009510272 9.294279679393382 0.03562789586346907 0.04870773700793185 9.142825129617834e-07 6.038919586692598 0.2445548431015656 RLS(ph)PGSDIYVTVSSMALAR ddPTM_PC-9_AZD4547_30min_R2 3 RLSPGSDIYVTVSSMALAR 19 1 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 RLS(0.94)PGS(0.06)DIYVTVSSMALAR;RLS(0.923)PGS(0.076)DIY(0.001)VTVSSMALAR;RLS(0.983)PGS(0.017)DIYVTVSSMALAR 94.594 0.00034609 5742800.0 29299.280000000002 26041.800000000003 32249.980000000003 48543.9 45413.9 35917.04 32905.5 45589.3 28250.059999999998 32939.1 True False 38615.84157711703 34459.302574844965 31822.3241934374 37352.85385077864 39108.96388597516 33671.14181092737 35834.0257535999 38544.52122289467 29743.300497959463 31785.912134881743 1.2148728472303347 1.0841061420109273 1.001145540779234 1.1751386492315807 1.2303867109434663 1.0593102273751265 1.1273555907894104 1.212629074771652 0.9357384608547783 1.0 14.956099868439685 -8.271702056223585 24.99688493227739 0.96786920526076 1.1330759075975563 0.47223884273439487 0.07183359395010415 725.9341638643733 1768144.40458238 0.06800156647001276 0.018356280865710208 5.34931218235892e-09 8.271702056223585 0.16520670233679624 RLS(ph)PGSDIYVTVSSMALAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLSPGSDIYVTVSSMALAR 19 1 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 RLS(0.886)PGS(0.111)DIY(0.003)VT(0.001)VSSMALAR 45.357 0.034738 2705900.0 14359.0 14397.0 15074.0 16711.0 15500.0 15432.0 14674.0 16100.0 14642.0 11980.0 True False 16789.695096822667 15826.239013541697 15433.421328463355 15774.736847792983 12462.886267680997 14622.71875351662 13283.972489440006 15677.392059360061 14856.111550057454 14151.879166372173 1.1863933333121226 1.1183136053866367 1.0905563245011585 1.1146743596622177 0.8806523940153067 1.0332704640570463 0.9386719836476208 1.1077957828111495 1.0497624644336057 1.0 13.788706014514945 -6.040383209828385 24.64948269101241 1.0047965228629576 1.1257778926598185 0.49876313270978 0.06182174448974749 390.1907498310608 238167.6606774041 0.018597189490089067 0.02401255984378968 9.112064603316484e-07 6.040383209828385 0.12098136979686092 RLS(ph)PGSDIYVTVSSMALAR ddPTM_PC-9_Lapatinib_30min_R1 1 RLSPGSDIYVTVSSMALAR 19 1 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 RLS(0.979)PGS(0.021)DIYVTVSSMALAR 67.995 0.045649 0.0 520.81 754.79 2056.1 916.88 605.67 0.0 918.44 2296.0 641.52 808.42 True False 513.3831538951429 753.042330129159 1887.0553947755213 984.3104138220177 570.0456813930354 0.0 965.9923292385665 2402.680541960089 569.265262094915 948.1543198480607 0.5414552706751483 0.7942191628150069 1.990240781772652 1.0381331321464116 0.6012161411492422 0.0 1.0188134030685683 2.5340606393536365 0.6003930480284457 1.0 9.888978078392535 -5.989957463370577 24.919930628952276 0.9752577332621697 1.1500279206207011 0.007907828122784677 0.6976282865401094 1603.1638877356168 3978109.4344399017 0.21298342883931687 0.3155185704035745 1.0233932228116894e-06 5.989957463370577 0.17477018735853145 RLS(ph)PIMLGK ddPTM_PC-9_AZD4547_30min_R2 1 RLSPIMLGK 9 1 Q6ICB0 Q6ICB0 DESI1 Desumoylating isopeptidase 1 1 RLS(1)PIMLGK 84.821 0.015939 0.0 44446.0 33375.0 59197.0 67258.0 65342.0 54928.0 59484.0 64220.0 49255.0 54743.0 True False 58578.90346576924 44162.81606630308 58412.00910136734 51752.707225741484 56270.39118502025 51493.34347681818 64777.960764222924 54296.27462878999 51858.51874392453 52826.4642324724 1.108893133713856 0.8359979549635695 1.105733839090853 0.9796738808411319 1.0651932133370166 0.9747641494651701 1.2262407054001534 1.0278233725779835 0.9816768829295814 1.0 15.688973230571952 -5.874090737397287 1.2254935382719752 1.0532851784320547 0.9875635212038277 0.020973748924051572 0.09803397113315977 1.5555491220578344 4.698934773277885 0.034760651559125375 0.07785873899718672 1.3363162900426164e-06 5.874090737397287 -0.06572165722822698 RLS(ph)PISGSR ddPTM_PC-9_AZD4547_30min_R2 1 RLSPISGSR 9 1 E9PQ01 E9PQ01 PCF11 1 RLS(1)PISGSR 55.261 0.042018 4870300.0 9714.6 9476.6 14919.0 16360.0 15981.0 13066.0 10146.0 15982.0 11321.0 12386.0 True False 12803.640723767323 12539.725624986595 14721.164312098575 12588.454759480359 13762.314002139634 12248.980954487812 11048.9743445936 13512.349129824383 11919.404947720435 11952.36991000498 1.0712219267117702 1.0491413601991983 1.2316523353059814 1.0532183035050589 1.1514297252982109 1.0248160864093194 0.9244170342606972 1.1305163102853426 0.9972419727189876 1.0 13.545009082979291 -6.822683974049583 8.477953748901742 1.017469603210596 1.1112501759353235 0.32793997463927427 0.06865353919077843 0.3551205510764167 44.46325725452378 0.023880835164108008 0.021102655747649277 1.5042361654523784e-07 6.822683974049583 0.0937805727247274 RLS(ph)PISGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLSPISGSR 9 1 E9PQ01 E9PQ01 PCF11 1 RLS(0.999)PISGSR 74.237 0.012708 5368900.0 9387.6 12148.0 12293.0 15069.0 15267.0 12796.0 16560.0 17483.0 17855.0 11897.0 True False 10976.73526644839 13353.973156664897 12586.111741462115 14224.732784357155 12275.5409450765 12124.955233929413 14991.316915982465 17024.089774769694 18116.095596658655 14053.831923399823 0.7810492772559756 0.9502015698957057 0.8955644133260243 1.0121604457694402 0.8734657573809145 0.8627508355028208 1.0667067172634759 1.2113486106536078 1.2890502530128531 1.0 13.778675929436481 -7.479607381513531 3.41894022473716 1.1849205023346074 0.9033042659997634 0.6581381736653288 0.0884133554114995 0.14005089544282515 3.3242748046812727 0.04145579780159487 0.024855619412981974 3.314306117801067e-08 7.479607381513531 -0.281616236334844 RLS(ph)PISGSR ddPTM_PC-9_Lapatinib_30min_R1 1 RLSPISGSR 9 1 E9PQ01 E9PQ01 PCF11 1 RLS(1)PISGSR 53.448 0.045818 5149200.0 12789.0 14470.0 12719.0 9859.0 12626.0 13514.0 11445.0 14072.0 14664.0 7944.6 True False 12606.626514784633 14436.495604034148 11673.292916759818 10584.063748659877 11883.363503671088 12936.037722672649 12037.566099184907 14725.836492361661 13012.385901234316 9317.813524485911 1.3529597347764237 1.5493436916393588 1.2527931457400425 1.1358956391267583 1.2753381973617812 1.388312578769531 1.291887422682571 1.5803961362463652 1.396506365687571 1.0 13.185775743033828 -6.7716610562937 24.729576671850253 1.365224436520143 1.313167980752087 0.0 0.16746394925916322 1045.1913151786487 2528640.823956868 0.05975363861559804 0.05327156631465889 1.6917607456882827e-07 6.7716610562937 -0.05205645576805584 RLS(ph)PPACTLR ddPTM_PC-9_Lapatinib_30min_R1 1 RLSPPACTLR 10 1 P28360 P28360 MSX1 Homeobox protein MSX-1 1 RLS(1)PPACTLR 58.246 0.03564 2197500.0 11445.0 10082.0 10174.0 10281.0 9569.0 8738.9 7788.1 6636.7 9383.9 6189.2 True False 11281.792201244045 10058.655748436237 9337.532992775721 11037.099036410606 9006.170233377841 8365.157618370873 8191.329710534037 6945.065310464513 8326.98636515225 7258.994973409388 1.554181018525384 1.3856815971470373 1.286339641641891 1.5204720594022847 1.2406910689935144 1.1523850958725688 1.128438542875413 0.9567530127662521 1.1471266195465142 1.0 12.825554101857211 -6.70003921098447 1.3542235131759723 1.0475447653433314 1.429916982371208 0.7855294088250514 0.08874852918029023 0.19247347609022264 0.7389290860395228 0.04026957751866032 0.038408177082516745 1.9950821775939623e-07 6.70003921098447 0.3823722170278765 RLS(ph)PPFPLEPAQK ddPTM_PC-9_AZD4547_30min_R2 2 RLSPPFPLEPAQK 13 1 Q8NEV8-2;Q8NEV8;E9PPH6 Q8NEV8-2 EXPH5 Exophilin-5 1 RLS(1)PPFPLEPAQK;RLS(1)PPFPLEPAQK 114.56 0.00013884 88842000.0 334255.0 272758.0 429320.0 468733.0 452344.0 390717.0 331392.0 420086.0 377381.0 403954.0 True False 440541.1370640941 360921.6894265975 423626.93628729554 360673.8487026595 389543.8436257972 366285.4042242942 360885.2460086298 355171.3613159434 397328.58922141884 389811.69341402804 1.1301383321925778 0.9258872823069836 1.086747635960093 0.925251486285147 0.9993128739010239 0.9396470408989347 0.925793792505155 0.9111357286522128 1.0192834025617772 1.0 18.572417843065956 -4.7521031142923595 24.99961684639542 0.9683458213210272 1.1301386487491496 0.44915101482916164 0.05304877010136064 340.39372934583986 911403.3603308398 0.012874217357557475 0.15896580108298256 1.7696887322410458e-05 4.7521031142923595 0.1617928274281224 RLS(ph)PPFPLEPAQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RLSPPFPLEPAQK 13 1 Q8NEV8-2;Q8NEV8;E9PPH6 Q8NEV8-2 EXPH5 Exophilin-5 1 RLS(1)PPFPLEPAQK;RLS(1)PPFPLEPAQK 130.02 3.9275e-05 77398000.0 218576.0 209917.0 239269.0 244995.0 270805.0 239902.0 207994.0 247636.0 220113.0 192494.0 True False 255576.59972721766 230756.1724668769 244974.08039273505 231268.72443450653 217742.70423995805 227321.11679666542 188291.3025738443 241135.81739203082 223331.73621211597 227391.63841833387 1.1239489785329386 1.0147962083036373 1.0773222889667327 1.017050257622226 0.9575668910013981 0.9996898671289808 0.8280484888694261 1.0604427632840734 0.9821457717862568 1.0 17.794819679264187 -6.000108769843838 2.9263897065836146 0.9685975648118714 1.0666355284670619 0.3544181168042895 0.060565408052512315 0.3030026456774141 5.288688275968212 0.01825205181208219 0.02710259355561013 9.997495795394515e-07 6.000108769843838 0.09803796365519046 RLS(ph)PPFPLEPAQK ddPTM_PC-9_Lapatinib_30min_R1 2 RLSPPFPLEPAQK 13 1 Q8NEV8-2;Q8NEV8;E9PPH6 Q8NEV8-2 EXPH5 Exophilin-5 1 RLS(1)PPFPLEPAQK;RLS(1)PPFPLEPAQK 99.711 0.0011175999999999998 67507000.0 161459.0 130629.0 167349.0 152014.0 150214.0 132559.0 120265.0 124590.0 139211.0 122578.0 True False 159156.56505204574 130326.53657632213 153590.21120582093 163193.61666383807 141378.70785208666 126889.7605801217 126491.73323883566 130378.90623815634 123531.5912231812 143765.44397508143 1.1070571665304496 0.906521991466262 1.0683388647444543 1.135137986929071 0.9833984018898975 0.8826165528492037 0.8798479644438075 0.9068862630212768 0.8592578842840194 1.0 17.133357420055255 -6.57684485673975 4.5423922978632705 0.8993807881838697 1.0465572302508328 0.5228102460985864 0.06653153044118101 0.1681814508718974 7.306702203505873 0.02234281087265185 0.022651673718473778 2.6494464328024926e-07 6.57684485673975 0.14717644206696312 RLS(ph)PPSSSAASSYSFSDLNSTR ddPTM_PC-9_AZD4547_30min_R2 3 RLSPPSSSAASSYSFSDLNSTR 22 1 P50402 P50402 EMD Emerin 1 RLS(0.391)PPS(0.391)S(0.165)S(0.053)AASSYSFSDLNSTR;RLS(0.967)PPS(0.021)S(0.002)S(0.007)AAS(0.002)SYSFSDLNSTR;RLS(0.837)PPS(0.094)S(0.028)S(0.039)AAS(0.001)SYSFSDLNSTR 73.212 0.00053622 111681000.0 150777.0 200387.0 265764.0 260188.0 248082.0 196546.0 237407.0 276880.0 215725.0 179840.0 True False 198720.9496435742 265158.17896863725 262239.7957128875 200205.67646452808 213640.09650702798 184255.94754942285 258535.76308169984 234094.5580694395 227127.7830886837 173543.85633903617 1.1450762581612335 1.5279030013636603 1.5110865993468214 1.1536315988818713 1.2310438468628908 1.0617255570802777 1.4897431031878365 1.3489072042522274 1.308763029011904 1.0 17.404940767370057 -8.62840796450318 16.956936293962464 0.9999999994960302 1.3137548174291227 0.26157078013123924 0.15538938140431477 8904.714844796177 1430856.8454292784 0.1558899499519536 0.04025061200309361 2.3528380529718185e-09 8.62840796450318 0.31375481793309246 RLS(ph)PPSSSAASSYSFSDLNSTR ddPTM_PC-9_Lapatinib_30min_R1 3 RLSPPSSSAASSYSFSDLNSTR 22 1 P50402 P50402 EMD Emerin 1 RLS(0.773)PPS(0.021)S(0.142)S(0.063)AASSYSFSDLNSTR;RLS(0.972)PPS(0.021)S(0.005)S(0.002)AASSYSFSDLNSTR;RLS(0.968)PPS(0.013)S(0.009)S(0.011)AASSYSFSDLNSTR 87.729 9.938899999999999e-05 93786700.0 131354.0 235639.0 138378.4 93955.0 140222.0 137316.0 157616.5 137092.0 188358.0 80466.3 True False 129480.86787262648 235093.39237311683 127001.46210807083 100864.76412469216 131974.41764705893 131443.31477923013 165777.11114654242 143461.7947989517 167143.13854232768 94374.79274039467 1.3719857189917364 2.491061283915183 1.3457138121344046 1.0687680597312679 1.3984074964815336 1.3927799040661548 1.7565825188359419 1.5201283163989046 1.7710570130956846 1.0 16.526113950527687 -5.324372155599879 24.999993261572403 1.424891789532973 1.931534221010947 0.27066789963849447 0.34357589027153734 246.9858687965985 98114.31391504106 0.08713964587148673 0.18139569385260695 4.738357719193357e-06 5.324372155599879 0.506642431477974 RLS(ph)PQPQIR ddPTM_PC-9_AZD4547_30min_R2 2 RLSPQPQIR 9 1 C9JU82;A0A0A0MR27;J3QT39;Q49A88-2;Q49A88-3;Q49A88-5;Q49A88-6;Q49A88 C9JU82 CCDC14 Coiled-coil domain-containing protein 14 1 RLS(1)PQPQIR;RLS(1)PQPQIR 85.522 0.005671 19090900.0 11003.0 13434.3 21923.0 30937.0 25124.0 23302.0 19436.5 26369.0 22029.0 19168.6 True False 14501.72512338251 17776.674752944877 21632.286695766274 23804.952621885328 21635.966271807538 21844.92225635045 21166.310846510292 22294.27694933921 23193.40796690516 18497.513148467755 0.7839824200683844 0.9610305239554545 1.169469999677129 1.2869271902021713 1.1696689224194312 1.1809653590196247 1.1442787296120185 1.2052580674168063 1.253866278171906 1.0 14.175043703829608 -5.038939937058091 2.3487607186589106 1.1877663504400884 0.7754372736111308 0.7539811141042904 0.0726699167494803 0.16002422179306725 1.509795803877112 0.018734013455028887 0.10779263678495948 9.142396721057276e-06 5.038939937058091 -0.4123290768289576 RLS(ph)PQPQIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLSPQPQIR 9 1 C9JU82;A0A0A0MR27;J3QT39;Q49A88-2;Q49A88-3;Q49A88-5;Q49A88-6;Q49A88 C9JU82 CCDC14 Coiled-coil domain-containing protein 14 1 RLS(1)PQPQIR 76.165 0.011420999999999999 5482800.0 6124.1 5805.2 5056.6 7003.8 6096.8 6363.3 5591.2 5745.4 4792.9 4477.4 True False 7160.789173511509 6381.501890769765 5177.168521262289 6611.399792625968 4902.175806244999 6029.597346050564 5061.561059217463 5594.589337754493 4862.987095224041 5289.1171769211005 1.3538722879420013 1.2065344134584977 0.978834150971868 1.2500006279827958 0.9268419742401419 1.1400007117181155 0.956976540679308 1.0577548484208878 0.9194326638183655 1.0 12.368811222357534 -1.5228787452814805 0.49313151688680196 1.0029566136237995 11.533458898378258 0.5565424918443136 0.0953486993238651 76.08689867832942 0.8237547330992202 0.05008306405959742 827.1062325198789 0.029999999999921048 1.5228787452814805 10.530502284754458 RLS(ph)PQPQIR ddPTM_PC-9_Lapatinib_30min_R1 2 RLSPQPQIR 9 1 C9JU82;A0A0A0MR27;J3QT39;Q49A88-2;Q49A88-3;Q49A88-5;Q49A88-6;Q49A88 C9JU82 CCDC14 Coiled-coil domain-containing protein 14 1 RLS(1)PQPQIR;RLS(1)PQPQIR 84.18799999999999 0.0061431 18360900.0 26641.0 19331.1 28707.0 20839.0 19262.1 23199.0 15108.7 19864.7 22374.0 12812.099999999999 True False 26261.094454638933 19286.340025649235 26346.821272224563 22371.569576866124 18129.141148745657 22206.83284951034 15890.954558563135 20787.6864816527 19854.004511334988 15026.654413949853 1.747634152699998 1.283475316218422 1.7533391363393398 1.4887924457820556 1.2064655677391263 1.4778294780569943 1.057517802752615 1.3833875398341928 1.3212524867081332 1.0 13.875236217967021 -1.522878754529458 0.09282241647701894 0.7800938981087417 3.1874126739858304 0.4921434708443392 0.1725984187840856 130.08633801723903 0.8681153849800491 2.8328558860751127 39.846999284522084 0.029999999361093405 1.522878754529458 2.407318775877089 RLS(ph)PS(ph)ASPPR ddPTM_PC-9_Lapatinib_30min_R1 1 RLSPSASPPR 10 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 2 RLS(1)PS(0.735)AS(0.265)PPR 72.705 0.022536 33318000.0 24681.0 20592.0 31410.0 23730.0 24074.0 24311.0 20686.0 23991.0 21664.0 17648.0 True False 24329.044414058913 20544.320489168702 28827.591046106285 25475.18336095943 22658.014651305068 23271.275201708955 21757.019862624642 25105.70944345145 19223.972187966454 20698.433285518142 1.1754051177912563 0.9925543738396245 1.3927426606861006 1.230778340058394 1.0946729319439827 1.1243012879622598 1.051143319037927 1.212928007503684 0.9287646037160064 1.0 14.337233950329376 -7.872519979305811 0.6897407209283762 0.9850564714867176 1.1822628842911471 0.2719354741494031 0.11157235753497445 1.0133644569740228 0.9728887571191224 0.10740653603570985 0.05149574762437021 1.3411582352733214e-08 7.872519979305811 0.19720641280442952 RLS(ph)QPESAEK ddPTM_PC-9_AZD4547_30min_R2 4 RLSQPESAEK 10 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 RLS(1)QPESAEK;RLS(1)QPESAEK;RLS(0.587)QPES(0.413)AEK;RLS(0.999)QPES(0.001)AEK 136.33 5.2782e-05 398241000.0 270206.0 261346.0 317567.0 442217.0 385278.0 364624.0 288696.0 340878.0 318821.0 283777.0 True False 356125.8873660547 345820.9836004206 313355.8540854084 340270.70283454313 331788.8000823703 341824.0036391522 314389.38472174224 288203.13769717654 335673.2271740283 273842.0536049969 1.300479172858337 1.262848342859894 1.1442941285322383 1.2425801601873983 1.2116064560374595 1.24825241097635 1.1480683137705094 1.0524429462280283 1.225791374097054 1.0 18.062984491042087 -14.522878745280149 0.05712382609357038 0.2001929862467898 1.5509593777259654 0.6041663394387277 0.057622554761665 303.4189397512491 1.2660916516057537 34.30755005631766 6.192953012754794 3.000000000001302e-15 14.522878745280149 1.3507663914791757 RLS(ph)QPESAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 RLSQPESAEK 10 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 RLS(0.997)QPES(0.003)AEK;RLS(0.999)QPES(0.001)AEK;RLS(1)QPESAEK;RLS(1)QPESAEK;RLS(1)QPESAEK;RLS(1)QPESAEK;RLS(1)QPESAEK 132.24 7.0119e-05 477238400.0 434850.0 502779.0 444170.0 559904.0 566770.0 544559.0 687032.0 597571.0 527573.0 470193.0 True False 508461.5163210078 552691.5763693462 454760.6973241061 528534.3941132589 455715.48709248827 516001.3673986693 621951.3552790632 581885.39442881 535287.7570549432 555435.2688542607 0.915428934446044 0.9950602839992965 0.8187465269574549 0.9515679391470904 0.8204655207303055 0.929003605520163 1.1197548844206642 1.0476205366452693 0.9637266249929046 1.0 19.083259262298746 -7.085510344969507 7.2654373586176035 1.0360181145033143 0.9010211336645475 0.507816731694442 0.06209232839029953 0.22182259752957295 16.452438715333006 0.02348365901985021 0.01820556452806461 8.212769896419307e-08 7.085510344969507 -0.13499698083876677 RLS(ph)QPESAEK ddPTM_PC-9_Lapatinib_30min_R1 4 RLSQPESAEK 10 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 RLS(1)QPESAEK;RLS(0.722)QPES(0.278)AEK;RLS(1)QPESAEK;RLS(0.998)QPES(0.002)AEK 142.39 0.00018626 336142000.0 180216.0 123386.0 167079.0 143864.0 215227.0 223883.0 265759.0 230850.0 239024.0 187316.0 True False 177646.08679243358 123100.30729781342 153342.4095635906 154444.23847623513 202567.77101256262 214308.04598676358 279518.7006512261 241576.13375935797 212102.60008569487 219693.32101711855 0.8086094104726623 0.5603279459197643 0.6979839389457002 0.7029992434963501 0.9220479260576997 0.9754873065534143 1.2723131470594227 1.0996061812026334 0.9654485584892578 1.0 17.745131484926496 -6.490322241390732 1.7776361889912544 1.0898410110070438 0.6744221103095781 0.7603806692266392 0.09817980400866132 0.1624380497992066 1.033059251729265 0.03738943659464855 0.04176224943460212 3.233536433019177e-07 6.490322241390732 -0.4154189006974657 RLS(ph)QRPTPEELEQR ddPTM_PC-9_Lapatinib_30min_R1 2 RLSQRPTPEELEQR 14 2 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 RLS(0.765)QRPT(0.235)PEELEQR;RLS(0.899)QRPT(0.101)PEELEQR 62.081 0.015862 18416600.0 47904.0 39550.0 47402.0 39861.0 38544.0 41227.0 27473.0 32410.0 35128.0 33450.0 True False 47220.88017548229 39458.424404944766 43504.79053701146 42792.51091239794 36276.91770041961 39463.81731483093 28895.41751357861 33915.886918521996 31171.514725760975 39231.78793067669 1.2036382399630239 1.0057768581607482 1.1089168460505865 1.0907611702024163 0.9246817342233192 1.0059143209217036 0.73653073279855 0.8645001593720889 0.7945473905201983 1.0 15.25973546515418 -6.574887179386501 1.2640470171153042 0.8446649540131601 1.1037432145532706 0.5972644883403538 0.08754204528494175 0.2883772404079065 0.9642356899684293 0.03762542845422644 0.040328748048604666 2.6614163502487866e-07 6.574887179386501 0.2590782605401105 RLS(ph)QSDEDVIR ddPTM_PC-9_AZD4547_30min_R2 2 RLSQSDEDVIR 11 1 H0Y917;A0A499FIZ0;Q9H7D7-3;Q9H7D7-4;Q9H7D7-2;Q9H7D7 H0Y917 WDR26 WD repeat-containing protein 26 1 RLS(0.999)QS(0.001)DEDVIR;RLS(0.981)QS(0.019)DEDVIR 153.09 0.00018626 84565000.0 30057.3 23388.5 42836.0 59163.0 43264.0 36766.0 33755.0 47977.0 33660.0 39295.0 True False 39614.89616932155 30948.375237954446 42267.96665145479 45523.88440923817 37257.54039099987 34467.016207921246 36759.12960790035 40563.257051782275 35439.198881748045 37919.29401046712 1.0447160793232697 0.8161643312613245 1.1146823208203 1.2005467295006047 0.9825483665575476 0.9089572236868936 0.9694043775644525 1.0697260618983393 0.9345954297557735 1.0 15.21064448363057 -6.483440329405239 24.98432634493691 0.9765934662347393 1.0401418651204921 0.0982642562805024 0.09853151005322572 1527.0074249834472 967363.2443138809 0.032856127033191615 0.03724857361944619 3.2851837851782144e-07 6.483440329405239 0.06354839888575281 RLS(ph)QSDEDVIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RLSQSDEDVIR 11 1 H0Y917;A0A499FIZ0;Q9H7D7-3;Q9H7D7-4;Q9H7D7-2;Q9H7D7 H0Y917 WDR26 WD repeat-containing protein 26 1 RLS(0.996)QS(0.004)DEDVIR;RLS(0.977)QS(0.023)DEDVIR 109.99 0.00091319 56782000.0 29181.0 31063.0 39135.0 32217.0 47615.0 48763.0 35134.0 34830.0 30365.0 26862.0 True False 34120.7669489785 34146.72935178481 40068.126820314006 30411.98593892326 38285.182557137465 46205.78243764458 31805.853171867606 33915.74940543549 30809.030680063843 31731.86796052499 1.0752839067471647 1.0761020874744578 1.2627093642945784 0.9584051583964838 1.2065215512923764 1.456131813454077 1.0023315744107677 1.068822971519587 0.9709176503063365 1.0 14.953644830463498 RLS(ph)QSDEDVIR ddPTM_PC-9_Lapatinib_30min_R1 2 RLSQSDEDVIR 11 1 H0Y917;A0A499FIZ0;Q9H7D7-3;Q9H7D7-4;Q9H7D7-2;Q9H7D7 H0Y917 WDR26 WD repeat-containing protein 26 1 RLS(0.998)QS(0.002)DEDVIR;RLS(0.994)QS(0.006)DEDVIR 155.09 0.00014659999999999999 75435000.0 40975.0 42402.0 45839.0 39831.0 46171.0 39505.0 39952.0 36403.0 48665.0 34633.0 True False 40390.68898610529 42303.82077417112 42070.294363657005 42760.30461232087 43455.31255567854 37815.46324065287 42020.51907336266 38094.416275685144 43183.835234831386 40619.26790442824 0.9943726480038791 1.041471768366343 1.0357226147611236 1.0527098792851266 1.0698201813465258 0.930973530336087 1.0344972039434925 0.937841035572484 1.0631367196581984 1.0 15.309876617209886 -6.734729374870446 24.999872445561255 0.9919801529173328 1.0395664080169145 0.2360320813168103 0.04091095847034605 307.44839596587 287763.0840942781 0.01264066949558351 0.012637199622920217 1.8419194127881975e-07 6.734729374870446 0.0475862550995817 RLS(ph)SASTGKPPLSVEDDFEK ddPTM_PC-9_AZD4547_30min_R2 2 RLSSASTGKPPLSVEDDFEK 20 2 O75152;A0A1B0GTU1;A0A494C0C4 O75152 ZC3H11A Zinc finger CCCH domain-containing protein 11A 1 RLS(0.799)S(0.145)AS(0.028)T(0.028)GKPPLSVEDDFEK;RLS(0.808)S(0.156)AS(0.032)T(0.004)GKPPLSVEDDFEK 100.27 0.00010298 55405000.0 219071.0 179276.0 172288.0 181821.0 203652.0 217972.0 167055.0 171088.0 175645.0 163572.0 True False 288731.021040128 237223.46106674272 170003.34854902077 139904.97755644744 175378.43508940254 204342.17638233758 181922.57137158347 144650.2808111243 184929.23611362555 157845.39406744213 1.8292014331236222 1.5028849113290246 1.0770244488501448 0.8863418434412514 1.1110773052678948 1.294571676225338 1.152536457882667 0.9164048255302275 1.171584620547188 1.0 17.26815263782443 -5.041577864274869 2.555967008628626 1.0770030575199356 1.8322180910633896 0.8178941760305865 0.11617442954669134 0.13740686725324686 1.5946483410952446 0.033375082134142364 0.17443297153411294 9.08703363834606e-06 5.041577864274869 0.755215033543454 RLS(ph)SASTGKPPLSVEDDFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLSSASTGKPPLSVEDDFEK 20 2 O75152;A0A1B0GTU1;A0A494C0C4 O75152 ZC3H11A Zinc finger CCCH domain-containing protein 11A 1 RLS(0.498)S(0.177)AS(0.064)T(0.26)GKPPLSVEDDFEK 60.826 0.036286 10140000.0 7344.7 8769.1 7161.7 8010.8 10494.0 9452.8 8956.7 10111.0 8657.7 7701.6 True False 8588.012645562607 9639.638295037063 7332.462088898495 7561.980847364012 8437.776031809319 8957.078527296655 8108.2565351074945 9845.59696349004 8784.302483740776 9097.839114167942 0.9439618065116815 1.0595525128626846 0.8059564471171786 0.8311842793073623 0.927448367235829 0.9845281296904798 0.8912288328423632 1.0821907092374963 0.9655372417018344 1.0 13.151308206954399 -7.748396640189662 24.925330842753105 1.0178979966437836 0.9207788739510732 0.26406485890684894 0.07292747578557447 303.17798479402876 579390.8614497565 0.03648912921822409 0.020902390990113366 1.7848567245410036e-08 7.748396640189662 -0.09711912269271039 RLS(ph)SASTGKPPLSVEDDFEK ddPTM_PC-9_Lapatinib_30min_R1 5 RLSSASTGKPPLSVEDDFEK 20 2 O75152;A0A1B0GTU1;A0A494C0C4 O75152 ZC3H11A Zinc finger CCCH domain-containing protein 11A 1 RLS(0.826)S(0.161)AS(0.011)T(0.002)GKPPLSVEDDFEK;RLS(0.401)S(0.099)AS(0.401)T(0.099)GKPPLSVEDDFEK;RLS(0.474)S(0.474)AS(0.026)T(0.026)GKPPLSVEDDFEK;RLS(0.411)S(0.411)AS(0.133)T(0.044)GKPPLS(0.001)VEDDFEK;RLS(0.407)S(0.407)AS(0.093)T(0.093)GKPPLSVEDDFEK 79.88 0.0004899 58751300.0 156080.9 148037.0 166785.0 135161.0 219245.0 255411.0 256633.0 269795.0 261814.0 227366.0 True False 153855.1577442683 147694.22942186627 153072.58110871795 145101.19082387866 206349.44015225445 244487.66692212087 269920.20102508675 282330.6606350701 232325.75029635563 266665.9101538485 0.5769584783278227 0.5538549315758302 0.5740238076190737 0.5441310092473571 0.7738125958177576 0.9168313519379651 1.0122036253878897 1.0587429809538986 0.8712240352068965 1.0 18.02467388089501 -6.568925109316714 1.9557447091936855 0.9881201121502555 0.5587112872718885 0.9417311520893099 0.04808790192220766 0.06975405330651505 0.5415290792240063 0.017887485732481095 0.01877380191567262 2.6982046766019804e-07 6.568925109316714 -0.42940882487836707 RLS(ph)SDCSVTQER ddPTM_PC-9_AZD4547_30min_R2 2 RLSSDCSVTQER 12 1 E7EX48;P51957-3;P51957-2;P51957 E7EX48 NEK4 Serine/threonine-protein kinase Nek4 1 RLS(0.981)S(0.01)DCS(0.007)VT(0.002)QER;RLS(0.968)S(0.031)DCSVTQER 158.31 8.2624e-05 25986000.0 37782.0 32802.0 42874.0 59845.0 48378.0 39966.0 37476.0 42103.0 39996.0 39949.0 True False 49795.89008558013 43404.60502192877 42305.462746626035 46048.65984603313 41661.54976506548 37466.91970205574 40811.29139936817 35596.9487806905 42110.10690654768 38550.397669529244 1.291708856350903 1.1259184767434023 1.097406649583406 1.1945054429991162 1.0807035020029205 0.9718945060758764 1.058647740789091 0.9233873301604567 1.0923391054881926 1.0 15.23445812199582 -1.5228787566589679 0.2944295297009793 0.9881286756049914 3.2662547575691256 0.6257001187151803 0.06222144214439013 35.28740540117931 0.5018281133434898 0.06534159617750908 42.06927460531293 0.029999999213992073 1.5228787566589679 2.2781260819641345 RLS(ph)SDCSVTQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLSSDCSVTQER 12 1 E7EX48;P51957-3;P51957-2;P51957 E7EX48 NEK4 Serine/threonine-protein kinase Nek4 1 RLS(0.851)S(0.129)DCS(0.018)VT(0.003)QER 93.478 0.0077791 10136000.0 19592.0 20320.0 24057.0 19922.0 23800.0 18550.0 17203.0 19373.0 15948.0 15635.0 True False 22908.53864036144 22337.235309798398 24630.61011668056 18805.834927995442 19136.560849729532 17577.205344591323 15573.407301065605 18864.479277390226 16181.209329348196 18469.501733408102 1.2403441614737172 1.2094119068406832 1.3335828151838058 1.0182101931845282 1.036116790043926 0.9516881179743593 0.8431958547585521 1.0213853925072423 0.8761042697800133 1.0 14.1728573256512 -5.882221006220693 4.558528253533649 0.9559935788989943 1.2549379625992094 0.8198002876512506 0.06426183917134633 0.08654137918238133 3.0485346035962513 0.018778036156222398 0.028685537359516424 1.3115323092257532e-06 5.882221006220693 0.29894438370021514 RLS(ph)SDCSVTQER ddPTM_PC-9_Lapatinib_30min_R1 2 RLSSDCSVTQER 12 1 E7EX48;P51957-3;P51957-2;P51957 E7EX48 NEK4 Serine/threonine-protein kinase Nek4 1 RLS(0.984)S(0.013)DCS(0.003)VTQER;RLS(0.964)S(0.035)DCS(0.001)VTQER 143.58 0.00012634 22982000.0 32426.0 41513.0 55095.0 40771.0 43993.0 44711.0 35848.0 36612.0 43704.0 39491.0 True False 31963.59929379988 41416.87919905112 50565.30177285022 43769.435348068975 41405.41823356581 42798.81475643163 37704.03403438885 38313.12717867717 38781.59529647736 46316.96673155015 0.6901056254192688 0.8942053446440138 1.0917230842408812 0.9449978795406339 0.893957898269735 0.924041831247079 0.8140436797797825 0.8271942202246821 0.8373086156797083 1.0 15.49925315479714 -7.239045997450178 23.549551957034904 0.8552361413370894 0.915544517376404 0.017752276121620447 0.10367438031958429 1171.7127471444437 1232208.9442974601 0.041008463423454156 0.0317316779944824 5.767053795358025e-08 7.239045997450178 0.060308376039314604 RLS(ph)SFVTK ddPTM_PC-9_AZD4547_30min_R2 1 RLSSFVTK 8 1 F8VPD4;P27708;H7C3Z5 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 RLS(0.812)S(0.174)FVT(0.014)K 62.408 0.028452999999999996 9647800.0 48928.0 37187.0 46273.0 50119.0 42362.0 36028.0 36666.0 48083.0 41731.0 37273.0 True False 64486.086234377886 49206.97051858014 45659.389785758896 38564.83888083108 36480.76752134654 33775.163464586476 39929.202968546124 40652.87718741996 43936.81546447495 35968.08361501822 1.7928696709171397 1.3680731796907333 1.269441827217454 1.0721960973402709 1.0142538566084252 0.9390314987614156 1.1101287295682878 1.1302486288272984 1.2215500813095708 1.0 15.134429674058557 -4.537582948734459 1.0278573563007294 1.0688005004922931 2.47029207126166 0.8812235913301997 0.0812820449521724 0.9607166038413655 0.5912114651199274 0.02844781359453453 1.6671679530174317 2.900127231584751e-05 4.537582948734459 1.4014915707693667 RLS(ph)SFVTK ddPTM_PC-9_Lapatinib_30min_R1 1 RLSSFVTK 8 1 F8VPD4;P27708;H7C3Z5 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 RLS(0.844)S(0.156)FVT(0.001)K 77.062 0.011036 8976400.0 55962.0 53779.0 68705.0 54168.0 44051.0 43111.0 40975.0 31828.0 53873.0 50372.0 True False 55163.971617826115 53654.47802967192 63056.340108969554 58151.695419150834 41460.006787598184 41267.243026649456 43096.48500778522 33306.84507382656 47805.25543216015 59078.73308352902 0.9337365366287056 0.9081859956917497 1.0673272228065005 0.9843084369621217 0.7017754888037218 0.6985126605254615 0.7294754433351313 0.5637704692606621 0.8091787507455558 1.0 15.85035126804708 -6.259440794544139 24.932962811925215 0.7249948456170298 0.9754419969441479 0.48047830631921107 0.1116927987977144 130.64199607820748 1629797.032597956 0.032172861920736325 0.039473169495698866 5.502489284132153e-07 6.259440794544139 0.25044715132711814 RLS(ph)SSESPQR ddPTM_PC-9_Lapatinib_30min_R1 1 RLSSSESPQR 10 1 J3KS33;Q9H2G4 J3KS33 TSPYL2 Testis-specific Y-encoded-like protein 2 1 RLS(0.597)S(0.201)S(0.201)ES(0.001)PQR 61.03 0.030088999999999998 969850.0 5592.4 5304.1 9557.8 6350.9 8435.4 7651.7 5569.9 5517.7 9300.9 5581.9 True False 5512.651350479441 5291.818682332934 8771.994578174932 6817.966371981334 7939.246356634483 7324.45462798389 5858.282168269988 5774.072485354175 8253.334699181003 6546.723977585774 0.8420473154746221 0.8083155331507332 1.3399059756006038 1.0414317749341842 1.2127052223091017 1.1187969208814754 0.8948417847349566 0.8819789111505311 1.2606816367145164 1.0 12.676557438086329 -5.208221091355717 24.997766943255243 1.085742348300619 0.8251809565003144 0.3646245707045901 0.14151388415963548 366.54528595217414 172172.68089459743 0.03675326006837573 0.09723987144251493 6.191258092409302e-06 5.208221091355717 -0.2605613918003046 RLS(ph)STPLPK ddPTM_PC-9_AZD4547_30min_R2 1 RLSSTPLPK 9 1 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 1 RLS(0.707)S(0.223)T(0.07)PLPK 74.237 0.012708 23050000.0 38681.0 34879.0 43251.0 40965.0 56270.0 39445.0 40576.0 71558.0 48242.0 46660.0 True False 50980.753385218515 46152.95465398009 42677.46348029862 31521.1521529409 48457.881790901556 36978.497914416934 44187.18539387245 60500.35533925496 50791.973632005065 45026.447602198685 1.132240185493316 1.0250187858863287 0.9478310138376237 0.7000586062534876 1.0762093030082904 0.8212617224684463 0.9813606834867148 1.3436626374295775 1.1280475439844568 1.0 15.458485039133327 -7.606047243970781 8.827667070384912 1.1759669053426656 0.94420206778732 0.3043642005196825 0.13980660391878794 0.31357756392930475 30.011323007646833 0.0655116819109118 0.03770971241471152 2.477152570236516e-08 7.606047243970781 -0.2317648375553456 RLS(ph)STPLPK ddPTM_PC-9_Lapatinib_30min_R1 1 RLSSTPLPK 9 1 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 1 RLS(0.697)S(0.228)T(0.075)PLPK 64.945 0.024051 15940000.0 55727.0 38329.0 41743.0 46579.0 25803.0 27879.0 23838.0 26929.0 29927.0 39976.0 True False 54932.32276091979 38240.25155542673 38311.05167263974 50004.57504298899 24285.31827064985 26686.680159123196 25072.214999770185 28180.219649147755 26556.306114719002 46885.79833532826 1.1716196526727052 0.8156041469515269 0.8171142015891093 1.0665185795783014 0.5179674684637066 0.5691847234478012 0.5347507324169496 0.6010395610116779 0.5664040510686779 1.0 15.51686337747388 -6.264977674011264 24.991776496891003 0.603650725632549 0.9460920098092128 0.49427442673766786 0.16455737287119238 246.7900839019484 1743131.24961604 0.04789674685995547 0.05647076816596704 5.432782593456367e-07 6.264977674011264 0.34244128417666386 RLS(ph)STSLASGHSVR ddPTM_PC-9_AZD4547_30min_R2 4 RLSSTSLASGHSVR 14 1 Q9BZL6-2;Q9BZL6;Q9BZL6-3;M0QZ82 Q9BZL6-2 PRKD2 Serine/threonine-protein kinase D2 1 RLS(0.789)S(0.154)T(0.053)S(0.004)LASGHSVR;RLS(0.908)S(0.075)T(0.016)S(0.001)LASGHSVR;RLS(0.87)S(0.127)T(0.003)SLASGHSVR;RLS(0.949)S(0.044)T(0.007)SLASGHSVR 135.57 1.9144000000000002e-05 204428000.0 47842.3 33481.3 87463.0 150045.0 114306.0 90014.3 55442.0 114371.0 57480.2 93490.4 True False 63055.15621834072 44303.47546249327 86303.18347269093 115454.44342214127 98436.58496518197 84385.69159127142 60376.230594614455 96697.5899341223 60518.48602384595 90217.32955226298 0.6989251015439646 0.49107500390851433 0.9566142547224856 1.2797368753334515 1.091105062117335 0.935360113296046 0.6692309658715674 1.0718294413503484 0.6708077741182479 1.0 16.461116962229127 -5.273027840002377 23.773903740498326 0.9668327454903693 0.5950000701162123 0.39517586790273185 0.1801028514147946 340.33428631121 698203.0044735709 0.049223557465540344 0.10403508097694533 5.333007076968992e-06 5.273027840002377 -0.3718326753741571 RLS(ph)STSLASGHSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLSSTSLASGHSVR 14 1 Q9BZL6-2;Q9BZL6;Q9BZL6-3;M0QZ82 Q9BZL6-2 PRKD2 Serine/threonine-protein kinase D2 1 RLS(0.941)S(0.058)T(0.001)SLASGHSVR 151.11 0.00011015 21446000.0 8306.9 6465.4 20888.0 37119.0 33146.0 23146.0 21499.0 22279.0 21227.0 20786.0 True False 9713.094101246343 7107.242183659968 21386.049138181144 35039.3427714217 26651.279240551903 21932.18301379574 19462.459080719018 21694.19985655175 21537.404717461388 24554.337258114545 0.39557549442864426 0.28944956277780276 0.870968290179106 1.4270123605084126 1.0854000643712904 0.8932101397502694 0.7926281567337844 0.8835180370988186 0.8771323978758114 1.0 14.58369026307494 -5.324209358787602 4.813932422850959 0.9904041552273719 0.3407467893185763 0.6979917220581453 0.1684010048335805 0.11624743360071034 5.447152946816604 0.04964900791021513 0.110562881475103 4.740134242178031e-06 5.324209358787602 -0.6496573659087956 RLS(ph)STSLASGHSVR ddPTM_PC-9_Lapatinib_30min_R1 2 RLSSTSLASGHSVR 14 1 Q9BZL6-2;Q9BZL6;Q9BZL6-3;M0QZ82 Q9BZL6-2 PRKD2 Serine/threonine-protein kinase D2 1 RLS(0.631)S(0.354)T(0.015)SLASGHSVR;RLS(0.633)S(0.333)T(0.034)SLASGHSVR 99.915 0.00095688 109206000.0 15796.400000000001 12381.1 19871.2 15587.8 21873.8 17010.0 10731.7 14850.8 26099.0 13645.5 True False 15571.140439295024 12352.432323642523 18237.466641050207 16734.178811376438 20587.226089545416 16282.52195224669 11287.334915388614 15540.822383510847 23159.45578534605 16004.106493514157 0.9729465650335059 0.7718289258227871 1.1395491931049786 1.0456178117883776 1.286371475838943 1.0173965012570596 0.7052774186402054 0.9710521727538454 1.4470945813020977 1.0 13.966154513267721 -5.266403118358741 24.989491544654697 1.0665283168303288 0.8723877431563051 0.15269008003374118 0.1912101000549351 769.281793450773 3872897.7767015398 0.05196226629938831 0.11385562468029217 5.414980308286104e-06 5.266403118358741 -0.1941405736740237 RLS(ph)TSPDVIQGHQPR ddPTM_PC-9_AZD4547_30min_R2 3 RLSTSPDVIQGHQPR 15 1 Q9Y385 Q9Y385 UBE2J1 Ubiquitin-conjugating enzyme E2 J1 1 RLS(0.971)T(0.021)S(0.008)PDVIQGHQPR;RLS(0.903)T(0.082)S(0.015)PDVIQGHQPR;RLS(0.95)T(0.043)S(0.007)PDVIQGHQPR 159.4 5.4575e-05 175667000.0 63668.0 53140.0 81738.0 78277.0 73663.0 64549.0 64571.0 68158.0 71021.0 68690.0 True False 83913.09962333161 70316.46579066198 80654.10071333949 60231.44701759443 63436.163965935324 60512.74082590187 70317.69390939809 57625.74721502751 74775.02506775483 66285.18400760872 1.265940509627301 1.0608172375683609 1.2167741844705657 0.9086713406525446 0.9570187503538292 0.9129150311924268 1.0608357653699276 0.869360899841702 1.1280805233816893 1.0 16.016398816291165 -5.758804195803754 24.999964920377913 0.971282384970868 1.1691413288754955 0.5384332503020488 0.08644166985249535 50.71716282947635 481141.23185558745 0.022130985292338253 0.03620304946150021 1.7425923542197556e-06 5.758804195803754 0.19785894390462744 RLS(ph)TSPDVIQGHQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RLSTSPDVIQGHQPR 15 1 Q9Y385 Q9Y385 UBE2J1 Ubiquitin-conjugating enzyme E2 J1 1 RLS(0.851)T(0.128)S(0.02)PDVIQGHQPR;RLS(0.333)T(0.333)S(0.333)PDVIQGHQPR;RLS(0.959)T(0.036)S(0.005)PDVIQGHQPR;RLS(0.422)T(0.422)S(0.157)PDVIQGHQPR 192.72 9.742100000000001e-09 127689000.0 277041.0 278914.0 235957.0 290435.0 360684.0 251052.0 263812.0 258194.0 235110.0 196924.7 True False 323938.56949083076 306602.7386415895 241583.1097519061 274162.8685529747 290010.55939175887 237886.39116821255 238821.8175265199 251416.68107915614 238548.03896557936 232625.58925493245 1.3925319674777017 1.3180095088575405 1.0385061700463107 1.1785585129782172 1.2466838249421421 1.022614889144955 1.026636056211327 1.0807782664169017 1.0254591497419339 1.0 17.827650279161183 -1.522878745280473 0.35698746353647304 1.0279338531299558 5.591221168366916 0.7000819085132808 0.07367711685616452 37.69426286781173 0.5275835108041739 0.06432639843049794 116.55066238530513 0.02999999999999064 1.522878745280473 4.56328731523696 RLS(ph)TSPDVIQGHQPR ddPTM_PC-9_Lapatinib_30min_R1 4 RLSTSPDVIQGHQPR 15 1 Q9Y385 Q9Y385 UBE2J1 Ubiquitin-conjugating enzyme E2 J1 1 RLS(0.972)T(0.024)S(0.004)PDVIQGHQPR;RLS(0.95)T(0.04)S(0.01)PDVIQGHQPR;RLS(0.776)T(0.22)S(0.005)PDVIQGHQPR;RLS(0.863)T(0.12)S(0.017)PDVIQGHQPR 176.46 2.438e-05 155678000.0 264222.0 235002.0 138505.0 93914.0 110070.0 137684.0 113611.0 122907.3 173336.0 56112.1 True False 260454.14582761994 234457.8673074803 127117.65354476155 100820.74884791985 103595.8990059461 131795.57627708022 119493.22167710759 128618.0218531581 153813.07437100055 65811.00172032647 3.9576079837601945 3.562593809221192 1.9315562781579698 1.5319740805097064 1.5741425642811533 2.0026374440730277 1.8157028240492616 1.9543544162986501 2.3371939394670185 1.0 16.00604116108746 -5.232620151677434 3.5232264728478757 1.783342653980399 3.875330355248604 0.8519025061776712 0.3343993249546215 0.07927178535808384 2.0815656188891514 0.08673439938871035 0.2508548389146191 5.853017846424072e-06 5.232620151677434 2.091987701268205 RLS(ph)VLEEEATEGGTSR ddPTM_PC-9_AZD4547_30min_R2 3 RLSVLEEEATEGGTSR 16 1 A0A1B0GVE3;O75808-2;O75808 A0A1B0GVE3 CAPN15 Calpain-15 1 RLS(1)VLEEEATEGGTSR;RLS(1)VLEEEATEGGTSR;RLS(1)VLEEEATEGGTSR 130.47 6.2711e-06 7762500.0 14067.599999999999 15882.999999999998 21297.5 30094.5 27983.8 25420.8 17949.1 21667.2 18635.2 24119.9 True False 18540.804175742604 21016.869141006497 21015.081234460704 23156.677980390064 24098.732405548777 23831.23335740425 19546.535127985906 18319.032102723744 19620.21862748519 23275.469642526183 0.7965813133096589 0.9029621942668328 0.902885379209038 0.9948962721714936 1.0353704039345537 1.023877658471073 0.8397912234721482 0.7870531673076696 0.8429569383054445 1.0 14.50652265771409 -10.26017753717037 8.550511362413271 0.9999968342825617 0.9078223514757807 0.10149958594937092 0.08553521092889967 0.0 0.0 0.09361682096906009 0.022705414187645476 5.493162705141973e-11 10.26017753717037 -0.09217448280678098 RLS(ph)VLEEEATEGGTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RLSVLEEEATEGGTSR 16 1 A0A1B0GVE3;O75808-2;O75808 A0A1B0GVE3 CAPN15 Calpain-15 1 RLS(1)VLEEEATEGGTSR;RLS(1)VLEEEATEGGTSR;RLS(1)VLEEEATEGGTSR;RLS(1)VLEEEATEGGTSR 118.23 5.9232e-05 8366700.0 23135.9 23168.000000000004 27767.0 30381.8 31570.0 27387.199999999997 24911.5 27894.1 22795.2 21025.7 True False 27052.350915145867 25467.965928022102 28429.070586933896 28679.606245124578 25384.08512714124 25950.967019589847 22551.70237635852 27161.90943124198 23128.536675718464 24837.492970650386 1.0891739736821549 1.0253839209181348 1.1446030652339814 1.154690059862897 1.0220067362328695 1.0448303719805865 0.9079701563683216 1.0935849871538275 0.931194493061303 1.0 14.60023193872206 -6.550267319342065 2.674912695019809 0.9948692111428936 1.1000377863653965 0.419490012096448 0.05940873259863108 0.28508604246749447 4.137081254489398 0.020550849401039992 0.021588834192270884 2.816648678404218e-07 6.550267319342065 0.10516857522250289 RLS(ph)VLEEEATEGGTSR ddPTM_PC-9_Lapatinib_30min_R1 2 RLSVLEEEATEGGTSR 16 1 A0A1B0GVE3;O75808-2;O75808 A0A1B0GVE3 CAPN15 Calpain-15 1 RLS(1)VLEEEATEGGTSR;RLS(1)VLEEEATEGGTSR 112.82 0.00013914 4980700.0 13777.5 14525.6 14204.4 10474.5 11792.1 11580.6 9599.1 11738.2 12129.5 10070.8 True False 13581.030323515937 14491.966865650198 13036.569062569639 11244.829671907688 11098.511862160607 11085.324733697113 10096.094429242981 12283.599624405886 10763.347980702501 11811.5243615025 1.1498118200374559 1.226934510915806 1.1037160542173496 0.9520218836916724 0.9396341676552922 0.9385177047788766 0.8547664230494544 1.03996734447266 0.911258162052619 1.0 13.527907546389818 -5.639639086079887 2.997217991956887 0.943681363394607 1.1868529895959217 0.7991482045252389 0.049831215967267535 0.09917895257877744 1.7734312745878968 0.013664038111941107 0.026302343257385813 2.292772235273544e-06 5.639639086079887 0.24317162620131472 RLS(ph)VYR ddPTM_PC-9_AZD4547_30min_R2 1 RLSVYR 6 1 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BT57;P29590-14;P29590-10;P29590-2 P29590;P29590-2 PML Protein PML 1 RLS(1)VYR 64.265 0.037056 13734000.0 15511.0 14743.0 19228.0 25274.0 14034.0 13305.0 18613.0 16080.0 14058.0 19335.0 True False 20443.175351157515 19508.386434921526 18973.024156647985 19447.469779407485 12085.621344473295 12473.036246705991 20269.52094184118 13595.205481640354 14801.077180024186 18658.08753511597 1.095673675701321 1.045572671808149 1.0168793624180013 1.042307779015713 0.6477417003070233 0.6685056130876633 1.0863664833650484 0.7286494639953383 0.7932794372503296 1.0 14.187513496231935 -6.193023988135643 11.772760846743198 0.8128867297284303 1.0475964925829888 0.4272792617410769 0.1298796497258928 1.0380678694037373 176.93781663773 0.03869968383780301 0.04997232076417814 6.411741605295748e-07 6.193023988135643 0.23470976285455847 RLS(ph)VYR ddPTM_PC-9_Lapatinib_30min_R1 1 RLSVYR 6 1 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BT57;P29590-14;P29590-10;P29590-2 P29590;P29590-2 PML Protein PML 1 RLS(1)VYR 73.26 0.030476 13119000.0 11790.0 10354.0 10796.0 10701.0 9202.6 12222.0 7848.6 8892.6 10783.0 10066.0 True False 11621.872437978805 10330.02594914786 9908.394553765153 11487.98723748954 8661.321161007727 11699.293550873548 8254.96210450526 9305.782660032353 9568.504989976102 11805.894687898106 0.9844126807172068 0.874988827381027 0.8392751939352782 0.9730721424497846 0.7336437762642595 0.9909705160140186 0.6992237625977803 0.7882318880560109 0.8104853755628119 1.0 13.527219757234896 -1.5228787452927348 0.57544159827591 0.8336037818243337 8.150973026323177 0.11591190104582005 0.10047992926801888 298.9924904334723 2.520374785884235 0.045386236805426604 2729.3458893965617 0.02999999999914363 1.5228787452927348 7.317369244498844 RLS(ph)YNTASNK ddPTM_PC-9_AZD4547_30min_R2 2 RLSYNTASNK 10 1 P49207 P49207 RPL34 60S ribosomal protein L34 1 RLS(0.816)Y(0.081)NT(0.1)AS(0.003)NK;RLS(0.882)YNT(0.118)ASNK 111.88 0.00070235 68801000.0 59802.0 75302.0 47401.0 138329.0 128144.0 66652.0 36287.0 93975.0 82263.0 76765.0 True False 78817.79204112722 99641.89888913109 46772.43176873677 106439.38621174557 110353.41752644883 62484.23990345334 39516.47270276641 79453.32308066853 86611.25423675706 74077.48071544748 1.0639912599604813 1.3451037741399947 0.6313987910631422 1.4368656328987388 1.4897026256919759 0.8434984464910861 0.533447848402949 1.0725705344363852 1.1691981611720212 1.0 16.176747414687377 -6.808437454156198 24.999979504834858 0.9038848940276849 1.1841435079556133 0.19260248779338296 0.27423732749356033 214.11567981295434 113894.32345796199 0.10075927565734744 0.08886159044520034 1.5543991347509956e-07 6.808437454156198 0.2802586139279284 RLS(ph)YNTASNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLSYNTASNK 10 1 P49207 P49207 RPL34 60S ribosomal protein L34 1 RLS(0.958)Y(0.001)NT(0.031)AS(0.009)NK 66.023 0.021677000000000002 9998000.0 111520.0 126820.0 134330.0 112200.0 133050.0 128500.0 104030.0 129800.0 85512.0 71672.0 True False 130398.13337959906 139409.8514758185 137532.93664936186 105913.79775730777 106979.80760741673 121761.23378867836 94175.52528802247 126392.8875344682 86762.45122718971 84665.56624476012 1.5401554511857918 1.6465944498947522 1.6244258764155333 1.2509666261620578 1.2635574573274364 1.438143500235718 1.1123238107895004 1.4928487830469162 1.0247666799554342 1.0 16.36948771972635 -1.522878749086664 0.12296504442731021 0.876226576136252 3.3850482164885323 0.5993647131065012 0.14551560605697647 63.21014801520771 0.5338829429489573 0.9227797011294788 27.244913783838626 0.029999999737068288 1.522878749086664 2.5088216403522803 RLS(ph)YNTASNK ddPTM_PC-9_Lapatinib_30min_R1 3 RLSYNTASNK 10 1 P49207 P49207 RPL34 60S ribosomal protein L34 1 RLS(0.927)YNT(0.073)ASNK;RLS(0.995)YNT(0.005)ASNK;RLS(0.996)YNT(0.004)ASNK 104.81 0.0011697 55437000.0 117258.0 94304.0 130974.0 100717.0 143969.0 49908.4 76090.0 102077.0 100216.0 136710.0 True False 115585.8794175162 94085.6448820203 120205.82329426047 108124.06416206273 135501.02647394428 47773.93407416275 80029.56788877054 106819.87007040948 88928.61875873558 160340.14134537525 0.7208792411411336 0.5867878379834922 0.7496926364517491 0.6743418289070966 0.8450848635718293 0.29795367319314586 0.4991237204686353 0.6662079076026118 0.5546247995826691 1.0 17.29077612556975 -10.932808774688983 6.990014926130696 1.0000284709757155 0.6206847646921895 0.3842776868800095 0.14367817199145363 6.604638197144347e-05 5.575193816094434e-06 0.14412931574134918 0.034953877405732345 1.1673234911037514e-11 10.932808774688983 -0.379343706283526 RLS(ph)YQGQSR ddPTM_PC-9_AZD4547_30min_R2 2 RLSYQGQSR 9 1 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 RLS(1)YQGQSR;RLS(1)YQGQSR 98.182 0.0020832 43688000.0 23244.0 22084.9 30519.0 54873.0 47415.0 42129.0 26933.0 34869.0 27300.0 36852.0 True False 30635.108494765373 29223.412031241845 30114.29811923966 42222.87762939887 40832.24569247551 39494.66697012222 29329.9848238655 29480.7972599078 28743.0222659454 35561.82269687581 0.8614605824874308 0.8217636165710143 0.8468153720896109 1.1873091542382683 1.148204523725459 1.1105917519124215 0.8247604481319853 0.8290013003888509 0.8082550354898019 1.0 15.118041649958796 -5.574857403815235 24.999991582948415 0.987348190061212 0.8397782405088691 0.2071780505374443 0.1286801116127891 172.44711159173536 82940.33061864557 0.040372593020083634 0.06992739897080104 2.661598825302292e-06 5.574857403815235 -0.14756994955234293 RLS(ph)YQGQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLSYQGQSR 9 1 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 RLS(1)YQGQSR 86.11399999999999 0.005461100000000001 12814000.0 6067.8 8207.7 10136.0 8893.2 9794.0 8288.9 8561.0 9000.7 8158.8 6668.6 True False 7094.958695487193 9022.506213200411 10377.68068099406 8394.942836143411 7874.936006817273 7854.215492225501 7750.040103727407 8764.441162029954 8278.10701506685 7877.5643913914455 0.900653849715341 1.145342108921401 1.3173717364131898 1.06567746311504 0.9996663455297116 0.997036025603109 0.9838117111675537 1.11258261139797 1.05084599804898 1.0 12.943533926575348 -5.989962538221109 24.995333078072495 1.0268455359743929 1.134874519913389 0.15439013307022642 0.10020025112804386 368.0870431155601 916602.8276250138 0.029186835549091194 0.04324092154553286 1.0233812642501295e-06 5.989962538221109 0.10802898393899607 RLS(ph)YQGQSR ddPTM_PC-9_Lapatinib_30min_R1 2 RLSYQGQSR 9 1 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 RLS(0.995)Y(0.005)QGQSR;RLS(0.998)Y(0.002)QGQSR 75.89 0.011604000000000001 35709000.0 28492.0 29274.0 34273.0 24828.0 28400.0 31065.0 25669.0 26221.0 27713.0 21764.0 True False 28085.698855207116 29206.217851589186 31455.206237605893 26653.933943780055 26729.56783654829 29736.42236605192 26998.0152206184 27439.323384466676 24591.67010917257 25525.878401292903 1.1002833443641475 1.1441807170134397 1.232286926353636 1.0441926238444361 1.0471556518577796 1.1649519714293457 1.0576723275172748 1.074960984812842 0.9634015222734503 1.0 14.639672987797844 -7.902473459338887 1.2873323442466351 0.9818988119849738 1.1221242972625098 0.4658451850051121 0.05553285708740019 0.43152599401868236 1.2880638354345402 0.05100610125247328 0.018256623107510278 1.2517757693786216e-08 7.902473459338887 0.1402254852775361 RLSDS(ph)PVFDAPPSPPDSLSDR ddPTM_PC-9_AZD4547_30min_R2 1 RLSDSPVFDAPPSPPDSLSDR 21 1 P47974 P47974 ZFP36L2 Zinc finger protein 36, C3H1 type-like 2 1 RLS(0.454)DS(0.546)PVFDAPPSPPDSLSDR 58.876999999999995 0.0056236 3013700.0 4803.4 4743.3 7484.6 7131.9 6056.7 9111.2 5844.4 7725.2 8495.8 5385.7 True False 6330.781283073301 6276.4789647129655 7385.3493136492325 5487.750641756603 5215.831751252056 8541.475223674375 6364.540277896989 6531.447847435825 8944.87064348054 5197.1482822795 1.2181259681697176 1.2076774846147098 1.421038791375407 1.055915733724196 1.0035949462970415 1.6434926924825077 1.224621644835091 1.2567368665823584 1.7211113013610742 1.0 12.343504506465178 -6.745155699605304 24.998164089013578 1.3762029884880143 1.1890940096941793 0.1555437474150766 0.2182467524785192 476.61478096543976 731681.9423355145 0.07049540432046014 0.07029545363449957 1.7982261146476457e-07 6.745155699605304 -0.18710897879383492 RLSELLR ddPTM_PC-9_AZD4547_30min_R2 2 RLSELLR 7 1 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 ; 126.52 1.6392e-05 1991300.0 11680.1 13421.900000000001 15727.3 21084.2 16672.0 16802.6 13863.8 19338.7 12672.3 15969.7 False True 15394.128838827612 17760.266695440096 15518.74572596474 16223.563437642775 14357.380579667852 15751.930765794958 15097.65134226067 16350.348274116803 13342.131906986808 15410.605663798371 0.99893081262799 1.1524703884391385 1.0070172493233283 1.052753135832562 0.931655827998721 1.0221487142973495 0.9796922763215676 1.0609802515760958 0.8657759596256043 1.0 13.911635942958762 -5.855278824058417 1.8872095625368495 0.9831505228287303 1.0705398164993583 0.23175807243065605 0.06373681076684107 0.47009086711854514 3.416066262144817 0.018893045762456193 0.03480109536734372 1.3954721577772715e-06 5.855278824058417 0.08738929367062798 RLSELLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLSELLR 7 1 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 118.74 0.0042977 2005000.0 4929.0 6325.2 5743.4 6726.7 8123.4 6856.1 6914.8 5972.5 7461.8 5616.0 False True 5763.382347812444 6953.124054209486 5880.344437965793 6349.824807255647 6531.678084314829 6496.554046525747 6259.780085183307 5815.728203386834 7570.9147086613 6634.136343768461 0.8687464425156217 1.0480827788142542 0.8863767841445231 0.9571441523387031 0.9845559008521324 0.9792614607066454 0.9435712142188949 0.876636822342313 1.1412057751530489 1.0 12.695692947143359 -8.26158007880323 24.99999953928601 1.0706028844535058 0.9477372989475078 0.4077671489558631 0.06128126488373821 12.001387956327399 2131313.19808139 0.0453201371236558 0.014462450698423154 5.4754513076016535e-09 8.26158007880323 -0.12286558550599802 RLSELLR ddPTM_PC-9_Lapatinib_30min_R1 1 RLSELLR 7 1 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 93.162 0.0089219 3190400.0 15005.0 13539.0 12256.0 13829.0 16494.0 13243.0 14411.0 11801.0 13640.0 11393.0 False True 14791.025948420003 13507.651277333678 11248.358989528133 14846.030792191645 15523.855348451681 12676.627760940788 15157.131066435446 12349.317541668563 12103.719564432351 13362.264869781746 1.1069250679104068 1.010880371626274 0.8418003309428381 1.1110414990923716 1.1617682705540653 0.9486885557558808 1.1343235008544639 0.9241934404096476 0.9058134741666776 1.0 13.705876941213877 -7.800194635713802 24.999928484550153 0.9362523966162649 1.039248610119762 0.197161444968741 0.0932266367561085 282.4691564708628 182209.2714372315 0.052130893834521706 0.025043575387264125 1.5841830574796918e-08 7.800194635713802 0.10299621350349708 RLSES(ph)ACR ddPTM_PC-9_Lapatinib_30min_R1 1 RLSESACR 8 1 G5E9C8;Q07889 G5E9C8 SOS1 Son of sevenless homolog 1 1 RLS(0.001)ES(0.999)ACR 80.916 0.017397 0.0 18097.0 17844.0 15265.0 15734.0 16167.0 13731.0 18145.0 14348.0 18773.0 14171.0 True False 17838.933461416647 17802.6833143321 14009.970624604031 16891.13084708535 15216.088845544935 13143.757138524354 19084.459315833134 15014.660459949202 16658.587051546085 16620.438468329416 1.0733130473909638 1.0711319889818476 0.84293628301686 1.0162867170605483 0.9155046585888514 0.7908189163342502 1.148252457490755 0.90338534019785 1.002295281396418 1.0 14.0206708222919 -5.157849979564359 12.5959670583059 0.9511755153674525 1.0726365576245824 0.20486497662137615 0.09437336780863417 1.238101220462019 145.98795836389993 0.02317629477147007 0.061372693921619696 6.952644446597086e-06 5.157849979564359 0.12146104225712995 RLSES(ph)SALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLSESSALK 9 1 Q96S55-2;Q96S55 Q96S55-2 WRNIP1 ATPase WRNIP1 1 RLS(0.228)ES(0.768)S(0.004)ALK 100.09 0.0018029 19576000.0 28227.0 44595.0 31998.0 35319.0 45054.0 35681.0 59994.0 45800.0 39071.0 42406.0 True False 33005.27359133738 49022.096881912374 32760.95367309078 33340.19093574295 36225.99212284514 33809.82554718937 54310.93400105384 44597.798529111256 39642.33945993002 50093.87211428869 0.6588684842736087 0.9786046638612588 0.6539912426483417 0.6655542789680466 0.7231621472621619 0.67492937000463 1.0841831886571667 0.8902845127915407 0.7913610544915833 1.0 15.612346511691774 -7.243473309370287 24.990662616333708 0.9323142442447887 0.7312110350221194 0.46220271364069465 0.11367630862574003 811.2469137353237 1128439.7550637021 0.04411491683081064 0.03410004487670984 5.7085615845541096e-08 7.243473309370287 -0.20110320922266933 RLSLGQGDS(ph)TEAATEER ddPTM_PC-9_Lapatinib_30min_R1 1 RLSLGQGDSTEAATEER 17 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RLS(0.049)LGQGDS(0.475)T(0.475)EAATEER 190.18 1.7813000000000002e-08 8810600.0 9038.3 11853.0 14901.0 11023.0 12999.0 10787.0 11378.0 9117.8 13533.0 11571.0 True False 8909.412184578772 11825.555106746146 13675.897299523402 11833.668191650047 12234.4243770173 10325.665155725164 11967.097167018424 9541.446274165373 12008.771031192304 13571.031932611653 0.6565021900191061 0.871382159106776 1.0077271476062004 0.8719799828348601 0.9015102490192776 0.7608607220879231 0.8818118788933862 0.7030744840587215 0.8848826744217451 1.0 13.728242806087911 -6.703509381425465 24.9999966056516 0.8297952261686129 0.871021844701152 0.0 0.11007171576087482 362.1959233223215 156305.465190487 0.03598800755913736 0.03598799416154874 1.9792042669346092e-07 6.703509381425465 0.04122661853253906 RLSS(ph)FVTK ddPTM_PC-9_Lapatinib_30min_R1 1 RLSSFVTK 8 1 F8VPD4;P27708;H7C3Z5 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 RLS(0.34)S(0.607)FVT(0.053)K 78.342 0.032705 9011200.0 92511.0 63701.0 85620.0 67283.0 64350.0 54052.0 60359.0 40658.0 62165.0 52711.0 True False 91191.77617556036 63553.50424827778 78580.65410275766 72231.21626950832 60565.05951696769 51740.32196136613 63484.09368114478 42547.11910932633 55163.32307352913 61822.02611700739 1.475069354779255 1.02800746335931 1.2710785950954127 1.1683734876757352 0.9796679811551192 0.8369237505001835 1.026884715182121 0.6882194224563196 0.8922923840950202 1.0 15.915833316519103 -6.305682414231695 2.057971408345501 0.8759092717169435 1.2384927940494532 0.605980089445461 0.13336632808777787 0.22121725124468367 1.8402059855574229 0.04425831885321205 0.05558109599570546 4.946722929001028e-07 6.305682414231695 0.3625835223325097 RLSS(ph)RS(ph)RS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 RLSSRSRSR 9 3 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 3 RLS(0.449)S(0.654)RS(0.897)RS(1)R;RLS(0.182)S(0.821)RS(0.997)RS(1)R 84.352 0.012898 21931400.0 87333.0 84281.0 116308.0 142834.0 135402.0 122955.0 102365.0 139859.0 106741.0 118676.0 True False 115103.07736075297 111523.18504521613 114765.67992570292 109905.82806330183 116603.76950864856 115266.60441290733 111475.28669271868 118247.00519009551 112383.11134392946 114521.18936216322 1.005081050955117 0.9738214007936457 1.0021348936812604 0.9596986258650727 1.0181851075603081 1.0065089705660215 0.9734031519720587 1.0325338555134083 0.9813302845513394 1.0 16.805255033103485 -6.285577757253918 24.994392495928338 1.0024165021796194 0.9855831483236004 0.1469361910608814 0.019817091377473818 1495.3769275113705 1548401.8649188138 0.005802473877031327 0.006583441476960468 5.181103198350652e-07 6.285577757253918 -0.01683335385601903 RLT(ph)VNEAVK ddPTM_PC-9_AZD4547_30min_R2 2 RLTVNEAVK 9 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 RLT(1)VNEAVK;RLT(1)VNEAVK 91.12299999999999 0.006829000000000001 14469500.0 64432.0 57662.0 67708.0 87434.0 73238.0 69865.0 65122.0 94505.0 71075.0 86528.0 True False 84920.03573114442 76300.11385813238 66810.1476803787 67277.44214183408 63070.16787990134 65496.330505532744 70917.73184196962 79901.42375885713 74831.87939751158 83498.68105707358 1.017022480547918 0.9137882526069987 0.8001341678045449 0.8057305970599481 0.7553432830488807 0.7843995818420683 0.8493275695396368 0.9569183937677095 0.8962043286212149 1.0 16.349465788543952 -7.730936838179652 6.842235405110515 0.945058284462966 0.8395219161299485 0.288666872913818 0.0744709550503067 0.2459400882919719 37.23925753387517 0.039761115847006485 0.022093326417639027 1.8580746653969295e-08 7.730936838179652 -0.1055363683330175 RLT(ph)VNEAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RLTVNEAVK 9 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 RLT(1)VNEAVK;RLT(1)VNEAVK 107.09 0.0021441 12719200.0 56481.0 62197.0 60892.0 70958.0 59814.0 59213.0 55556.0 70337.0 57319.0 51846.0 True False 66042.11774940047 68371.50711434685 62343.89621419594 66982.45330894002 48093.87607839171 56107.76604147098 50293.333489391385 68490.72827821173 58157.181938105685 61245.26938728985 1.0783219407817006 1.116355725076391 1.0179381499648377 1.093675543908062 0.7852667897379282 0.9161159156092299 0.8211790721558765 1.1183023434039383 0.949578351437131 1.0 15.902310793541114 -6.212489827876116 24.98138681063457 0.9313460859869477 1.0752263559099295 0.38909438259528784 0.08889873620959422 425.183749203014 216992.07974010217 0.027044592803521002 0.034914358716781446 6.130701514215992e-07 6.212489827876116 0.14388026992298186 RLT(ph)VNEAVK ddPTM_PC-9_Lapatinib_30min_R1 1 RLTVNEAVK 9 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 RLT(1)VNEAVK 92.792 0.0057347000000000006 6724000.0 86085.0 90390.0 79288.0 88088.0 90353.0 83343.0 70979.0 69890.0 87884.0 59651.0 True False 84857.41211394436 90180.70750854495 72769.24670053099 94566.28537295377 85038.61418083266 79778.614172022 74653.9453170857 73137.34454598911 77985.57846045248 69961.59587003861 1.2129141861139985 1.2890030078225427 1.0401313148388995 1.3516885113458688 1.2155042080343805 1.1403201024776448 1.0670703603697613 1.0453927420673736 1.1146912458274867 1.0 16.094275578007576 -7.011083680786398 2.518976064375128 1.06001982603472 1.2226693873294445 0.49637076042992223 0.07836179304758505 0.25583584625315064 3.255389511690257 0.03199150019220049 0.02531635768712314 9.748017927337337e-08 7.011083680786398 0.16264956129472452 RLT(ph)VSSLQESGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RLTVSSLQESGLK 13 1 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 RLT(0.736)VS(0.248)S(0.017)LQESGLK 91.14 0.004466899999999999 5747200.0 55576.0 69443.0 48223.0 40989.0 43516.0 32533.0 33930.0 34808.0 25265.0 30346.0 True False 64983.919123965235 76336.84210720116 49372.81920674589 38692.51921813096 34989.35218221977 30826.912208926642 30715.904768072767 33894.32688212454 25634.45282831593 35847.489581196154 1.8127885629696265 2.12948920549359 1.3773020031127776 1.0793648222001904 0.976061436686308 0.8599461934175981 0.8568495347073016 0.9455146588536523 0.7150975738552837 1.0 15.12958446931141 -5.5577542262136665 1.9034963506750993 0.8935577895883893 1.9940502821540351 0.9234869961330575 0.12065864027820822 0.07909386764800617 0.5639413553391125 0.034069226872418014 0.08739610923942305 2.768507942503302e-06 5.5577542262136665 1.1004924925656459 RLT(ph)VSSLQESGLK ddPTM_PC-9_Lapatinib_30min_R1 1 RLTVSSLQESGLK 13 1 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 RLT(0.468)VS(0.063)S(0.468)LQES(0.002)GLK 63.54600000000001 0.038223 4511600.0 37146.0 54232.0 48971.0 40348.0 46551.0 54038.0 38402.0 34262.0 47535.0 42321.0 True False 36616.291228257876 54106.429136004124 44944.79341352661 43315.326516982335 43812.96170278733 51726.920708730526 40390.26765757092 35853.93759958041 42181.10773425894 49636.12846081217 0.7376943440938694 1.090061429322016 0.9054854761489027 0.8726572329503877 0.8826828977481143 1.0421223877194419 0.8137271965008134 0.7223354985852123 0.8498065631279244 1.0 15.59910297148409 RLTLLS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 RLTLLSR 7 1 M0R0E1 M0R0E1 ZNF799 1 RLTLLS(1)R 72.243 0.018037 1699300.0 5088.9 2994.4 5994.7 6341.4 5876.2 4491.8 3871.6 6101.0 3113.7 4590.7 True False 6707.064344304401 3962.28124131649 5915.206361132601 4879.488203653347 5060.391060595268 4210.92703592288 4216.16489971699 5158.23063703282 3278.283825255462 4429.980990300332 1.5140165068405165 0.8944239828550293 1.3352667594024095 1.1014693323373697 1.1423053669248808 0.9505519425800965 0.9517343096840587 1.1643911448665416 0.7400220977095455 1.0 12.113084792639157 -1.5228787453070929 0.27983172131064094 0.9393349941654475 3.9503515067968853 0.3665920299947779 0.16969478034888666 61.79919070846323 0.8709514720391003 0.1798831415551944 90.96058321442413 0.029999999998151807 1.5228787453070929 3.011016512631438 RLTVSSLQESGLK ddPTM_PC-9_Lapatinib_30min_R1 1 RLTVSSLQESGLK 13 1 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 71.268 0.016636 2890900.0 34423.0 45577.0 44191.0 37862.0 50736.0 38357.0 42938.0 44469.0 45773.0 33101.0 False True 33932.121707594924 45471.46925674251 40557.78656219304 40646.49778392943 47751.80823081385 36716.56052453418 45161.11954275243 46535.192082065856 40617.562728941484 38822.46374568993 0.8740331868134482 1.1712669642660367 1.0446989358498857 1.0469839845865527 1.230004580430969 0.9457555492884053 1.163272888567414 1.1986666376173045 1.0462386672574546 1.0 15.244604056614447 -4.749852895238578 24.93404212271551 1.0990639725210052 0.8740326718298786 0.3567829579689028 0.08841818135972594 541.7363499834327 1165737.613000997 0.02093186567445761 0.32618358044197365 1.7788818530536834e-05 4.749852895238578 -0.22503130069112653 RLVEVDSSR ddPTM_PC-9_AZD4547_30min_R2 2 RLVEVDSSR 9 1 Q03252 Q03252 LMNB2 Lamin-B2 0 ; 118.03 0.001153 5468000.0 19451.5 20091.1 29140.0 37539.0 33066.0 27826.0 26755.0 31910.0 26723.0 25740.0 False True 25636.672383665813 26585.155172125902 28753.584560262225 28884.96352176855 28475.356660706424 26086.03582118307 29136.143168697192 26979.04271885219 28135.523223914253 24838.850434646254 1.0321199224222843 1.070305376735303 1.157605285957821 1.1628945388502605 1.146403966464882 1.050211075179115 1.1730069088888628 1.086163097194736 1.1327224380992151 1.0 14.60031078536983 -10.040070833697627 15.192482112631174 0.9999999999972355 1.1141437670190713 0.3337357371649534 0.04757764270705513 0.0 0.0 0.04696571382995613 0.01139085875902596 9.118621019559069e-11 10.040070833697627 0.11414376702183571 RLVEVDSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RLVEVDSSR 9 1 Q03252 Q03252 LMNB2 Lamin-B2 0 ; 91.65799999999999 0.00962 1888400.0 17692.0 16920.5 21975.0 24974.0 27391.0 19733.7 19138.5 21645.0 21253.0 18918.0 False True 20686.906167071997 18600.255416311207 22498.967340651576 23574.78774680043 22023.930177938724 18698.830032806563 17325.562729259083 21076.841684773222 21563.784918274236 22347.68364519441 0.9256845808053336 0.8323124540162783 1.0067695470304232 1.054909677489993 0.9855128848074013 0.8367234085501077 0.7752733126318767 0.9431331684930815 0.964922596034299 1.0 14.44783768224329 -6.74411258850368 24.90150792524974 0.8924102311516517 0.9616421775967745 0.10212007660128308 0.08096465527382726 510.8175302111619 734128.9837161851 0.029122178136539598 0.029054788119218425 1.8025503788112912e-07 6.74411258850368 0.06923194644512276 RLYSMTFMSPGPLVR ddPTM_PC-9_Lapatinib_30min_R1 1 RLYSMTFMSPGPLVR 15 1 Q7RTY7 Q7RTY7 OVCH1 Ovochymase-1 0 64.244 0.022996 11073000.0 75802.0 52903.0 62861.0 56454.0 62678.0 72990.0 42889.0 53264.0 78071.0 47220.0 False True 74721.04957961557 52780.50635385061 57692.81123047715 60605.815485023304 58991.40326968918 69868.3878480003 45109.5825625113 55738.839889791896 69277.82185592358 55381.914083305004 1.3491958668532258 0.9530278472220844 1.041726566974484 1.094325042537543 1.065174511320696 1.2615740897453431 0.8145183009503401 1.0064448080640551 1.250910572569169 1.0 15.757127295853998 -7.238476001603819 24.998834784155893 1.0185053980355947 1.1113329636980254 0.1159439758251507 0.1440789474748149 2098.535765512988 2284551.2069025286 0.054748178447613684 0.04237903659065377 5.7746278147245265e-08 7.238476001603819 0.09282756566243067 RMADY(ph)VT(ph)CES(ph)TK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RMADYVTCESTK 12 1 H0YCZ0;H7BY22;H0YEM9;Q8NCP5-3;Q8NCP5-4;Q8NCP5-2;Q8NCP5;A0A0A0MTE9 H0YCZ0 ZBTB44 Zinc finger and BTB domain-containing protein 44 3 RMADY(0.999)VT(0.985)CES(0.508)T(0.508)K 48.284 0.044608 0.0 5687.6 4689.5 4009.5 5505.4 4179.8 4240.3 4101.4 4483.0 4186.3 3189.9 True False 6650.398344779482 5155.042568174193 4105.101686113428 5196.950286747619 3360.7981949453565 4017.93120337847 3712.8857004354145 4365.326000131132 4247.516717798495 3768.2036187654962 1.7648723417335455 1.368037157679669 1.0894054837350595 1.379158562681439 0.8918833839574704 1.0662723169653945 0.9853198170994262 1.1584634063806931 1.1271993627536578 1.0 11.87966120923228 -1.5228849038733885 0.7170589969538413 1.0604309703833754 102.01150493454229 0.7659360589157482 0.11798299076118438 143.9069575100746 0.7130300439553133 0.044869199310334895 23356.285678347947 0.029999574582479777 1.5228849038733885 100.95107396415891 RMAQSVVEVMEDS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 RMAQSVVEVMEDSK 14 1 A0A3B3IRZ7;A0A0U1RR16;Q8NEY4-2;Q8NEY4 A0A3B3IRZ7 ATP6V1C2 V-type proton ATPase subunit C 2 1 RMAQSVVEVMEDS(1)K 89.74700000000001 0.0050046000000000005 10226000.0 16838.0 15442.0 25063.0 35151.0 26444.0 21543.0 25226.0 38500.0 31977.0 23363.0 True False 22192.133747842836 20433.32451523151 24730.648244126707 27047.480027536327 22772.707056666073 20195.91280441841 27471.06513076266 32550.70964198716 33667.23893766065 22545.068481143757 0.9843453687623035 0.9063323330475369 1.096942697903576 1.1997071576943001 1.01009704520138 0.8958017945835857 1.2184955283564078 1.4438061995336993 1.4933305244035633 1.0 14.460524271749609 -7.4887047927554145 5.324329686430603 1.3496293851686005 1.0235376519883101 0.45117751446222576 0.1484192167873768 0.15834392376212222 12.120400094836093 0.06583853415279059 0.041805489639994385 3.2456015884313783e-08 7.4887047927554145 -0.3260917331802904 RMAQSVVEVMEDS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 RMAQSVVEVMEDSK 14 1 A0A3B3IRZ7;A0A0U1RR16;Q8NEY4-2;Q8NEY4 A0A3B3IRZ7 ATP6V1C2 V-type proton ATPase subunit C 2 1 RMAQSVVEVMEDS(1)K 76.357 0.015774 6609600.0 6535.8 27790.0 50233.0 39986.0 45087.0 42765.0 39111.0 31205.0 49399.0 39705.0 True False 6442.598293481074 27725.653962412514 46103.036644987515 42926.70382938572 42435.07130445254 40936.04064008405 41135.976208407264 32654.898219453215 43835.16442546875 46567.956346413084 0.13834831499916825 0.5953805177999419 0.9900163172726093 0.9218077664834473 0.9112504527530361 0.8790602777490614 0.8833536928784674 0.7012310777938717 0.9413160435769299 1.0 15.50704994984191 -4.878435592807148 2.617129179345964 0.8912782732714827 0.06404556857302654 0.8940891295106072 0.08140866249075926 0.11512916762806268 1.218782083198229 0.021753905181632536 0.19332293258029762 1.3230139004478411e-05 4.878435592807148 -0.8272327046984561 down RMEDEGGFPVPQENGQPES(ph)PR ddPTM_PC-9_AZD4547_30min_R2 7 RMEDEGGFPVPQENGQPESPR 21 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RMEDEGGFPVPQENGQPES(1)PR;RMEDEGGFPVPQENGQPES(1)PR;RMEDEGGFPVPQENGQPES(1)PR;RMEDEGGFPVPQENGQPES(1)PR;RMEDEGGFPVPQENGQPES(1)PR;RMEDEGGFPVPQENGQPES(1)PR;RMEDEGGFPVPQENGQPES(1)PR 125.98 7.697800000000001e-07 106046400.0 95529.0 85836.4 138045.0 187619.0 163604.0 133080.0 107334.4 151036.0 125734.0 141368.0 True False 125905.23487336258 113581.33767771134 136214.43310299917 144366.33823465425 140890.40861060354 124758.48656231725 116886.95366571547 127696.8566620044 132380.04254895158 136418.74934907042 0.9229320417767085 0.8325933071492808 0.9985022861809967 1.0582587725184858 1.0327789199275752 0.9145259515837028 0.8568246976566491 0.9360652936001612 0.970394782100043 1.0 17.057682415968948 -5.362273002470345 0.005088809184099816 1.8840469088548601 9.041127923317112e-05 0.03914869013933664 0.06822263409882498 120487.01860371765 116.80416138376496 20973.366889546214 22280.02839739752 4.342371719140482e-06 5.362273002470345 -1.8839564975756269 RMEDEGGFPVPQENGQPES(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RMEDEGGFPVPQENGQPESPR 21 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RMEDEGGFPVPQENGQPES(1)PR;RMEDEGGFPVPQENGQPES(1)PR 82.62700000000001 0.00023090000000000003 44598000.0 14297.2 12405.6 19198.2 20719.4 22250.5 22252.0 21252.1 18185.4 22361.0 14985.6 True False 16717.433577428306 13637.145982245813 19655.95789757895 19558.559191201122 17890.674251550707 21085.06594759278 19238.947236120224 17708.05251902402 22687.987322144167 17702.370654055674 0.9443612894636959 0.7703570470162704 1.1103573799069508 1.1048553650479682 1.0106371966317342 1.191087135143796 1.08680061061271 1.0003209663315373 1.2816355371559385 1.0 14.1116549546505 -5.272671114790203 24.864545605359815 1.0982422897800914 0.8573591696009771 0.5230713254030324 0.09199358824489301 426.9148479850674 945094.8737684401 0.02254285682903545 0.047625538761551824 5.337389356017124e-06 5.272671114790203 -0.24088312017911429 RMEDEGGFPVPQENGQPES(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 8 RMEDEGGFPVPQENGQPESPR 21 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RMEDEGGFPVPQENGQPES(1)PR;RMEDEGGFPVPQENGQPES(1)PR;RMEDEGGFPVPQENGQPES(1)PR;RMEDEGGFPVPQENGQPES(1)PR;RMEDEGGFPVPQENGQPES(1)PR;RMEDEGGFPVPQENGQPES(1)PR;RMEDEGGFPVPQENGQPES(1)PR;RMEDEGGFPVPQENGQPES(1)PR 149.09 4.2993e-05 109297100.0 186176.1 156532.0 198866.9 158752.9 174332.0 172744.9 160625.5 152011.8 205931.0 142628.8 True False 183521.19467348486 156169.5597712971 182516.83113043354 170428.1178501495 164078.13450989928 165357.0033150299 168941.90244339238 159074.82317435948 182736.88223043407 167281.99803906982 1.0970767735008897 0.9335706268574259 1.0910727589935023 1.018807282600396 0.9808475295206466 0.9884925171470613 1.00992279159611 0.9509380868179641 1.0923882089676777 1.0 17.35192267332679 -4.719430747427853 24.185366609014785 1.007443770457874 1.0970783538669373 0.23107997168304595 0.04910875264376384 10253.334956046814 5902455.657077803 0.011541391624056005 5.124846777380767 1.907959942912606e-05 4.719430747427853 0.08963458340906327 RMEDEGGFPVPQENGQPES(ph)PRR ddPTM_PC-9_AZD4547_30min_R2 3 RMEDEGGFPVPQENGQPESPRR 22 2 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RMEDEGGFPVPQENGQPES(1)PRR;RMEDEGGFPVPQENGQPES(1)PRR;RMEDEGGFPVPQENGQPES(1)PRR 97.62299999999999 0.00034708 49879000.0 31404.0 32245.3 52470.8 70540.0 60568.0 53514.0 37366.0 62845.7 41680.0 45186.4 True False 41389.81875622146 42667.96263379064 51775.00290818835 54278.09283213603 52159.17867978183 50167.76112034752 40691.50161246643 53134.34111551774 43883.119708593564 43604.43788966971 0.9492111527947729 0.9785233957550699 1.1873792075749776 1.2447836839331212 1.1961896816961104 1.1505196156245536 0.9331963346351638 1.218553516271924 1.0063911343067646 1.0 15.412187353900174 -10.534220118144843 14.689095974300061 0.9999934393927409 1.1030408412725967 0.05759053961997562 0.11350533101034535 0.0 0.0 0.1148581396702261 0.027857190695428725 2.922670673758412e-11 10.534220118144843 0.10304740187985584 RMEDEGGFPVPQENGQPES(ph)PRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RMEDEGGFPVPQENGQPESPRR 22 2 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RMEDEGGFPVPQENGQPES(1)PRR;RMEDEGGFPVPQENGQPES(1)PRR;RMEDEGGFPVPQENGQPES(1)PRR 70.295 0.0047913999999999995 40019000.0 42954.0 39748.0 56973.0 46473.0 69846.0 49393.0 55269.0 55919.0 49945.0 44656.0 True False 50225.263819828746 43693.918754619415 58331.45239130569 43869.26847749888 56160.17769370631 46802.74412859296 50033.52020709146 54451.18550107798 50675.351138343125 52751.77930329849 0.9521055873974706 0.8282927956495924 1.1057722253485829 0.8316168488890345 1.0646120080767532 0.8872258859648826 0.9484707599988563 1.032215144592729 0.9606377606143509 1.0 15.686932135904865 -1.5228787457957902 0.18300091971722868 1.0008687113996153 0.6324138100555411 0.05535751513024345 0.08601253585768658 171.69039255571977 1.956689268506832 0.17862651667918283 17.670637650604817 0.029999999964393793 1.5228787457957902 -0.3684549013440742 RMEDEGGFPVPQENGQPES(ph)PRR ddPTM_PC-9_Lapatinib_30min_R1 6 RMEDEGGFPVPQENGQPESPRR 22 2 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RMEDEGGFPVPQENGQPES(1)PRR;RMEDEGGFPVPQENGQPES(1)PRR;RMEDEGGFPVPQENGQPES(1)PRR;RMEDEGGFPVPQENGQPES(1)PRR;RMEDEGGFPVPQENGQPES(1)PRR;RMEDEGGFPVPQENGQPES(1)PRR 117.29 3.7367e-06 68509300.0 82887.3 68696.5 92385.5 83990.40000000001 88558.7 93532.4 81782.4 84169.7 88083.4 64154.7 True False 81705.31190233062 68537.43747495051 84789.92080834293 90167.33419976091 83349.85137910304 89532.23728667366 86016.69250764357 88080.53153859684 78162.51993267745 75243.75441423559 1.085875001033608 0.9108721116922855 1.1268698839979903 1.1983364586430296 1.1077311602533995 1.1898959320102027 1.1431738511358733 1.170602559963869 1.03879080119226 1.0 16.199284215912748 -5.350278982496605 8.85195324268206 1.1337193434944441 0.9986814548923049 0.3109885747455594 0.07189534597502494 0.32163718546852765 29.537995297951888 0.01749627872935489 0.03652314689563557 4.463967432690883e-06 5.350278982496605 -0.13503788860213928 RMEEEER ddPTM_PC-9_AZD4547_30min_R2 1 RMEEEER 7 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 75.854 0.029789 3327000.0 10698.0 8019.1 10807.0 10410.0 9052.0 9355.7 9232.6 7904.1 10417.0 15237.0 False True 14099.741467776612 10611.117252952537 10663.692118831643 8010.135332896737 7795.286048893561 8770.686600023082 10054.283514083863 6682.702963148846 10967.621353273014 14703.557267781849 0.9589340328324285 0.7216700734184518 0.7252457296301841 0.5447753347721093 0.530163273208344 0.59650099906376 0.6837993916012838 0.4544956598898591 0.7459161856909997 1.0 13.84387761159972 -10.317894164271879 7.984435704590846 0.9998241155765354 0.6512108570472143 0.3568713639826544 0.13521887240583744 1.9460333161859864e-10 0.0 0.13474765922254636 0.03268110775172309 4.8095654124405094e-11 10.317894164271879 -0.3486132585293211 RMEEEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RMEEEER 7 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 76.035 0.029544 6314600.0 3232.1 4906.3 4414.0 5218.4 9682.6 9460.6 4945.0 7000.3 9831.7 6420.5 False True 3779.2306931151597 5393.365039392904 4519.246500188218 4926.029966281067 7785.364037125686 8964.469481565535 4476.57380130032 6816.549542430949 9975.470012750988 7584.4858253499615 0.49828436365240086 0.7111049006600318 0.5958540373407175 0.6494876620134986 1.0264854093476343 1.1819482148154583 0.5902277233267508 0.8987490647879774 1.3152467078795946 1.0 12.888835663900183 -6.23130968016757 6.587897404739079 0.9855972350285924 0.6175180052164239 0.5167390398492708 0.18363985544688824 0.18306279398983763 28.122222724281162 0.056612825564800934 0.0719261003609586 5.870705837937624e-07 6.23130968016757 -0.36807922981216856 RMEEEER ddPTM_PC-9_Lapatinib_30min_R1 1 RMEEEER 7 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 76.035 0.029544 2974500.0 6181.5 6427.4 5387.9 5194.6 5441.5 3911.5 6858.2 6520.5 8126.1 6815.9 False True 6093.350676451737 6412.517750198274 4944.92765989545 5576.628212677611 5121.441668400618 3744.2142631518486 7213.28403856968 6823.46623425556 7210.85304637344 7994.01923338413 0.7622386810135585 0.8021644135429039 0.6185784041205141 0.6976000494705893 0.6406591626666057 0.4683769395394362 0.9023350867666178 0.8535714057028811 0.902030985397173 1.0 12.964705328508078 -7.310913658672997 22.934239124932862 0.902282518326603 0.6694479743851645 0.642439799043673 0.09098567454990901 109.42604365446846 50724.619827792376 0.03994651707835626 0.026932055043213915 4.8874951712202197e-08 7.310913658672997 -0.23283454394143854 RMEEEQHHWDDR ddPTM_PC-9_Lapatinib_30min_R1 1 RMEEEQHHWDDR 12 1 Q96KR1 Q96KR1 ZFR Zinc finger RNA-binding protein 0 46.378 0.028539 3927700.0 7748.4 2407.6 7164.9 5274.7 4504.4 4093.2 5326.8 5620.5 7100.3 2012.6 False True 7637.906395117464 2402.025350122504 6575.829579313817 5662.619033883379 4239.460047991133 3918.1433777152324 5602.595639767429 5881.648948644025 6300.589444526324 2360.475228379068 3.2357494386257097 1.0176024392223628 2.785807493446742 2.39893177687439 1.7960197154461812 1.6598959949288732 2.3735032557891813 2.491722377736172 2.6692037979373 1.0 11.204861627556463 -11.412530857346727 2.7677190022883145 0.39136870252282085 2.229670351453138 0.28442828886367166 0.6012059740451969 27999727.214269586 4348621.897445339 108730718.77304074 0.14484824498349325 3.8678457196827205e-12 11.412530857346727 1.8383016489303174 RMEELHNQEVQK ddPTM_PC-9_AZD4547_30min_R2 2 RMEELHNQEVQK 12 1 Q15233;Q15233-2;H7C367;C9JYS8 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 ; 71.085 0.010006999999999999 10165800.0 29778.8 32620.0 60067.0 92596.0 72519.0 62842.0 35012.0 72960.0 43337.0 53040.0 False True 39247.83896248145 43163.77708113277 59270.472332919424 71249.42279393901 62450.98861905791 58912.47980574951 38128.000172768705 61685.70845400997 45627.70534576098 51183.08574411951 0.7668126763340111 0.8433211177794593 1.1580089686118442 1.3920501618471675 1.2201489556778624 1.1510146164354313 0.7449335970750705 1.2051971380232211 0.891460619898307 1.0 15.643379507261715 -10.618267955373682 14.470041993667419 0.9999188661618532 1.053927003249917 0.0003268208665662131 0.2082691659241688 0.0 0.0 0.2147782043595772 0.052091366038531324 2.408418999621123e-11 10.618267955373682 0.054008137088063846 RMEELHNQEVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RMEELHNQEVQK 12 1 Q15233;Q15233-2;H7C367;C9JYS8 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 ; 89.805 0.0025842 8266600.0 38262.0 28426.0 54343.0 51057.0 65676.0 58449.0 44888.0 49018.0 54490.0 37368.0 False True 44739.00089105293 31247.945419110674 55638.74321697518 48196.44181902737 52807.25925911085 55383.831546416084 40635.88367902299 47731.32943886411 55286.81316504788 44142.52259507478 1.0135125557152618 0.7078876235903468 1.2604341561391215 1.0918370538344564 1.1962900204756952 1.2546594143352279 0.9205609759048288 1.0813004475686614 1.2524615702686763 1.0 15.429881456638991 -5.264658863279575 24.99983156497595 1.1327599580143446 0.8607000896788922 0.4194806325836935 0.12775149584761228 236.83694249503068 1839093.4343846994 0.03238075377944009 0.07226364308312297 5.436772202703636e-06 5.264658863279575 -0.27205986833545237 RMEELHNQEVQK ddPTM_PC-9_Lapatinib_30min_R1 1 RMEELHNQEVQK 12 1 Q15233;Q15233-2;H7C367;C9JYS8 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 57.175 0.026049 3578400.0 13899.0 12244.0 24448.0 11811.0 13426.0 18212.0 14102.0 14538.0 22864.0 13097.0 False True 13700.797711235567 12215.649770269121 22437.979812009107 12679.620340340982 12636.309076531594 17433.11521424554 14832.13255838406 15213.488553578294 20288.81555140625 15360.798999344463 0.8919326209411543 0.7952483312092318 1.4607299928191673 0.8254531773303001 0.8226335802630359 1.1349094024984974 0.9655834022056429 0.990409975042805 1.3208177225854003 1.0 13.90696564003638 -8.148578239970158 13.766200933864761 1.1603670741979086 0.9887396118211103 0.10918138208951511 0.1992995975171996 1.9628449358900524 227.69993436437733 0.13267368723712109 0.050136545748656586 7.102672008646954e-09 8.148578239970158 -0.17162746237679838 RMGESDDSILR ddPTM_PC-9_AZD4547_30min_R2 1 RMGESDDSILR 11 1 Q8WVC2;P63220 Q8WVC2 RPS21 40S ribosomal protein S21 0 78.342 0.017161000000000003 6612800.0 8890.0 8922.6 11022.0 15132.0 17575.0 10895.0 9566.7 14057.0 7480.6 9488.9 False True 11716.835076512823 11806.655959047057 10875.84107835314 11643.551187069483 15135.014616582446 10213.73392768596 10418.1177668464 11884.813647725021 7876.009244052423 9156.69649919637 1.2795919442717296 1.2894012551451561 1.18774724916433 1.2715886333123927 1.6528902773954295 1.115438731488191 1.137759427514141 1.2979368322154263 0.8601365399348613 1.0 13.160611489552133 -8.029596730978602 1.2429709391909984 0.9433840860919123 1.3011924197359088 0.41610930286857994 0.1528216539884654 0.46893313812806 1.3154155368866236 0.14154901199669687 0.048310661726084565 9.341212870277118e-09 8.029596730978602 0.35780833364399656 RMGESDDSILR ddPTM_PC-9_Lapatinib_30min_R1 1 RMGESDDSILR 11 1 Q8WVC2;P63220 Q8WVC2 RPS21 40S ribosomal protein S21 0 150.09 0.00020686 3747700.0 22552.0 12637.0 15862.0 15030.0 16501.0 13328.0 11291.0 10241.0 15178.0 11324.0 False True 22230.404344469698 12607.739802914959 14557.887589090677 16135.356338610205 15530.443622214207 12757.992509085476 11875.592732712696 10716.834246608569 13468.49380857435 13281.338311718468 1.673807550317067 0.9492823318709399 1.0961160123634435 1.2148893402085514 1.1693432738258986 0.9605954015815387 0.8941563307844176 0.8069092131440421 1.014091614298444 1.0 13.69711290864374 -6.777195390227212 3.283068363565386 0.9136789441380717 1.2030956743769692 0.38332637537968384 0.18082149404365166 0.2717108372329317 6.091861123226418 0.0645700045778284 0.05956434245419338 1.670338955356906e-07 6.777195390227212 0.28941673023889747 RMILLS(ph)T(ph)PSQS(ph)DALR ddPTM_PC-9_AZD4547_30min_R2 1 RMILLSTPSQSDALR 15 1 Q96PT4-2;Q96PT3-2;O43812;Q96PT4;Q96PT3 Q96PT4-2 DUX3;DUX5;DUX1 Putative double homeobox protein 3;Double homeobox protein 5;Double homeobox protein 1 3 RMILLS(1)T(1)PS(0.009)QS(0.992)DALR 54.412 0.044898 0.0 13082.0 13360.0 16878.0 22930.0 17252.0 18814.0 12560.0 22204.0 17354.0 16355.0 True False 17241.803877496146 17678.358730960575 16654.186692110707 17643.84276496851 14856.857591196616 17637.55760582686 13677.815668055944 18772.881997160595 18271.297011106835 15782.416428074559 1.0924692017900095 1.1201300391183076 1.0552368053402392 1.1179430504433245 0.941355061748877 1.1175448123680403 0.8666490160356658 1.1894808429820953 1.15769958893018 1.0 13.946030491231905 RMKDS(ph)Y(ph)IEVLLPLGS(ph)EPELREK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RMKDSYIEVLLPLGSEPELREK 22 3 H7C5Q2;Q9Y305-3;Q9Y305-2;Q9Y305;Q9Y305-4;C9J7L8 H7C5Q2 ACOT9 Acyl-coenzyme A thioesterase 9, mitochondrial 3 RMKDS(1)Y(1)IEVLLPLGS(1)EPELREK 45.369 0.025693 5751600.0 20243.0 26377.0 22373.0 30979.0 26815.0 20138.0 32646.0 21904.0 18483.0 26475.0 True False 23669.740082525343 28995.53424047994 22906.457170074988 29243.347065273112 21560.79324308813 19081.927829077093 29553.534543427755 21329.043209206404 18753.278908599365 31274.707924015333 0.7568332896995575 0.927124061747504 0.7324275329997725 0.935047807203265 0.689400306965999 0.6101392817300908 0.9449659646776136 0.68199016473718 0.5996308248237557 1.0 14.93270879060586 -6.280416059687417 24.51338095870183 0.7407737554639233 0.8367035659978921 0.07707526647166774 0.1367751293826168 1515.1411047218965 1957198.6680275854 0.040999730169729125 0.04656791409733171 5.243049287217143e-07 6.280416059687417 0.09592981053396876 RMNS(ph)TGGQTPR ddPTM_PC-9_AZD4547_30min_R2 5 RMNSTGGQTPR 11 1 Q96ST2-3;Q96ST2;A0A1B0GW95;Q96ST2-2 Q96ST2-3 IWS1 Protein IWS1 homolog 1 RMNS(0.786)T(0.203)GGQT(0.01)PR;RMNS(0.615)T(0.384)GGQTPR;RMNS(0.677)T(0.323)GGQTPR;RMNS(0.799)T(0.201)GGQTPR;RMNS(0.787)T(0.213)GGQTPR 116.98 0.0017735 40628100.0 55507.399999999994 43672.200000000004 81935.4 134978.0 101353.0 70319.4 53332.8 77063.6 51728.799999999996 68825.1 True False 73157.59857435642 57788.38459358205 80848.88306036075 103860.90748931176 87281.88543012686 65922.31680170001 58079.315880676266 65155.19136535689 54463.07876156176 66415.55419773006 1.1015130334763779 0.8701031752522383 1.217318503729718 1.5638039724866364 1.3141783801167162 0.9925734656288254 0.8744836444150501 0.9810230773860463 0.8200349966126337 1.0 16.019233532809302 -6.903089962918145 5.372236580338086 0.9194648244695462 1.2128108223178218 0.4107419686237824 0.1691435744143527 0.24459691865283387 11.045573389398294 0.06889606684090802 0.06059939424633521 1.2500000692899648e-07 6.903089962918145 0.29334599784827553 RMNS(ph)TGGQTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RMNSTGGQTPR 11 1 Q96ST2-3;Q96ST2;A0A1B0GW95;Q96ST2-2 Q96ST2-3 IWS1 Protein IWS1 homolog 1 RMNS(0.704)T(0.296)GGQTPR 110.92 0.0018047 6113200.0 2862.9 2448.5 3779.6 7323.5 15737.0 25391.0 23971.0 32839.0 25594.0 20161.0 True False 3347.532425147548 2691.570898427232 3869.7199982128186 6913.188038107354 12653.447818999732 24059.451261699098 21700.29334498886 31977.011045796604 25968.263830909083 23816.02970561182 0.1405579547273894 0.11301509662599267 0.16248384159938248 0.2902745807576141 0.5312996320296902 1.0102209125154862 0.9111633472591602 1.3426675831808268 1.0903691401086104 1.0 14.53964530570529 -6.5847528371104564 1.2865844503176358 1.1372851077361201 0.12465547628556213 0.9421149606944085 0.10548792130318653 0.08841508426898581 0.3059001889196315 0.04558697111994459 0.04834699391202529 2.6016397704589356e-07 6.5847528371104564 -1.012629631450558 down RMNS(ph)TGGQTPR ddPTM_PC-9_Lapatinib_30min_R1 4 RMNSTGGQTPR 11 1 Q96ST2-3;Q96ST2;A0A1B0GW95;Q96ST2-2 Q96ST2-3 IWS1 Protein IWS1 homolog 1 RMNS(0.673)T(0.327)GGQTPR;RMNS(0.669)T(0.331)GGQTPR;RMNS(0.96)T(0.038)GGQT(0.003)PR;RMNS(0.765)T(0.217)GGQT(0.018)PR 98.337 0.0039998 8729170.0 21506.1 9800.920000000002 13906.49 14746.009999999998 38089.7 60108.200000000004 49303.3 46794.200000000004 84344.40000000001 55907.4 True False 21199.419070264277 9778.226571906733 12763.152072803778 15830.480766647333 35849.33873323144 57537.512405057874 51855.983631100324 48968.42936262578 74844.64548609301 65570.91959807207 0.3233051968801058 0.149124438574966 0.19464653158805237 0.2414253279301696 0.5467261852201549 0.8774852138378368 0.7908381329552835 0.7468010157976427 1.1414304686416752 1.0 16.000768507601492 -6.527480443405941 1.8974598708707096 0.9018463360732427 0.20765584104339074 0.8948754887488654 0.11060323743913535 0.1033291329647219 0.7508902422979307 0.041537263643996486 0.04495678585752394 2.9683804087665256e-07 6.527480443405941 -0.694190495029852 down RMNSTGGQT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 RMNSTGGQTPR 11 1 Q96ST2-3;Q96ST2;A0A1B0GW95;Q96ST2-2 Q96ST2-3 IWS1 Protein IWS1 homolog 1 RMNSTGGQT(1)PR;RMNSTGGQT(1)PR;RMNSTGGQT(1)PR 77.633 0.010098000000000001 4861500.0 15375.9 14337.5 18168.699999999997 26965.9 26025.199999999997 21376.6 14469.2 18128.9 16563.8 20212.7 True False 20265.116361412085 18971.816489906218 17927.771166782302 20749.32837400191 22412.050207651875 20039.91782272343 15756.930769445456 15327.495065678464 17439.328652332093 19505.059525267054 1.0389671631178796 0.9726612966922727 0.9191343991315938 1.0637921072285381 1.1490377754868717 1.0274215157745874 0.8078381277962144 0.7858214965108448 0.8940925624831346 1.0 14.251560780715131 -7.251597474764915 24.393446222833745 0.8540898394458541 1.028075846307935 0.4868839902433808 0.07788150213966041 403.3512234891087 999719.3248012828 0.03161771825958288 0.02417187773731744 5.6027665255139254e-08 7.251597474764915 0.17398600686208077 RMS(ph)ADMSEIEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RMSADMSEIEAR 12 1 O43318-3;O43318;Q9UG54;O43318-4;O43318-2 O43318-3 MAP3K7;DKFZp586F0420 Mitogen-activated protein kinase kinase kinase 7 1 RMS(1)ADMSEIEAR 65.043 0.025889 7416400.0 33310.0 30269.0 41158.0 40130.0 47681.0 46639.0 41406.0 43162.0 35180.0 30552.0 True False 38948.725097511204 33273.906279147996 42139.36281258421 37881.646203215416 38338.250330922434 44193.1687367329 37483.72392651991 42029.04323391923 35694.44094597877 36090.83575050105 1.0791860118387666 0.9219488988610094 1.167591770495345 1.0496195340305885 1.0622710594999225 1.22449834750971 1.0385939573593699 1.164535050517242 0.9890167463213491 1.0 15.139344931461311 -3.085166353955807 6.990076473362565 1.0755786788477917 1.2401570068800523 0.0 0.0880884665404703 0.0 0.0 0.019319225088928683 0.0 0.000821927755032512 3.085166353955807 0.16457832803226058 RMS(ph)ADMSEIEAR ddPTM_PC-9_Lapatinib_30min_R1 4 RMSADMSEIEAR 12 1 O43318-3;O43318;Q9UG54;O43318-4;O43318-2 O43318-3 MAP3K7;DKFZp586F0420 Mitogen-activated protein kinase kinase kinase 7 1 RMS(0.993)ADMS(0.007)EIEAR;RMS(0.991)ADMS(0.009)EIEAR;RMS(0.997)ADMS(0.003)EIEAR;RMS(1)ADMSEIEAR 112.12 0.00045449 14760500.0 67453.59999999999 45974.700000000004 62394.7 47719.6 54974.7 55287.9 51810.799999999996 49287.2 63987.5 43999.6 True False 66491.69929452486 45868.24840682715 57264.84861650713 51229.05857191906 51741.19623041874 52923.36539938972 54493.309711808586 51577.26324376974 56780.553931753275 51604.8722342183 1.2884771614730472 0.8888356161148037 1.1096791085268067 0.9927174771290287 1.0026416884743306 1.025549780632867 1.0559721854262243 0.9994649925626546 1.1002944387507478 1.0 15.6552196625683 -4.742306126543257 24.99999220120126 1.0222341058325566 1.288478047972647 0.6505307217650738 0.05912052153477336 778.5641256034984 1017238.8156455113 0.013474133514625923 0.4886531417525315 1.8100637607253985e-05 4.742306126543257 0.2662439421400904 RMS(ph)DEFVDSFK ddPTM_PC-9_AZD4547_30min_R2 1 RMSDEFVDSFK 11 1 Q92934;F5H1R6;F5H3B1 Q92934 BAD Bcl2-associated agonist of cell death 1 RMS(1)DEFVDSFK 60.255 0.023957 7634200.0 33126.0 32834.0 37586.0 49201.0 42044.0 44650.0 39153.0 45160.0 39352.0 43520.0 True False 43659.378936396344 43446.94839613468 37087.58508174385 37858.469597872456 36206.91633226699 41858.028441595074 42637.54115058873 38181.55967356206 41432.066381299745 41996.378046457074 1.0395986741547005 1.034540367935372 0.8831138971250558 0.9014698733303335 0.8621437851667664 0.9967056776965634 1.01526710478276 0.9091631576257599 0.9865628491930166 1.0 15.357977288399468 -9.828358753926832 15.47093519859875 0.9999989663747533 0.9555323536674587 0.03600947354056383 0.06210837223049165 0.0 0.0 0.06436457007734593 0.015610701233903953 1.484708674989644e-10 9.828358753926832 -0.04446661270729457 RMS(ph)DEFVDSFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RMSDEFVDSFK 11 1 Q92934;F5H1R6;F5H3B1 Q92934 BAD Bcl2-associated agonist of cell death 1 RMS(0.999)DEFVDS(0.001)FK;RMS(1)DEFVDSFK 75.819 0.0079297 7454400.0 46719.0 62697.0 51244.0 56113.0 56157.0 55099.0 53328.0 48185.0 44594.0 40666.0 True False 54627.60395768915 68921.1438099621 52465.85130395225 52969.170530800555 45153.438976397556 52209.51144375405 48276.38577871453 46920.19480622766 45246.102886440545 48038.42388812111 1.1371647846922264 1.434708681751835 1.0921642938607308 1.1026417239283888 0.9399442221825901 1.0868281516759828 1.0049535740628714 0.9767221946228346 0.9418731761853025 1.0 15.551901197410379 -5.58981198122992 2.289084274679518 1.002071099119907 1.2843769263797848 0.6108416719778798 0.08610088354855938 0.17904944103251444 1.8775531369072325 0.023401933536741026 0.052113144835505484 2.571508823119426e-06 5.58981198122992 0.28230582725987774 RMS(ph)DEFVDSFK ddPTM_PC-9_Lapatinib_30min_R1 3 RMSDEFVDSFK 11 1 Q92934;F5H1R6;F5H3B1 Q92934 BAD Bcl2-associated agonist of cell death 1 RMS(1)DEFVDSFK;RMS(1)DEFVDSFK;RMS(1)DEFVDSFK 74.611 0.0084298 11675700.0 69828.0 75468.0 78569.0 65418.0 85965.0 81807.0 77686.0 85814.0 80903.0 83794.0 True False 68832.23991511317 75293.25848274007 72109.3601051105 70229.05794805071 80908.70771369271 78308.3053114313 81708.20095948273 89801.23171940919 71790.8521936415 98277.68125151332 0.7003852658973195 0.7661277466452301 0.7337307839057318 0.7145982389258833 0.8232663477949816 0.7968066026204242 0.8314013916381909 0.9137500048417798 0.7304898862022758 1.0 16.584576198926307 -14.522878743017717 0.06928903923099196 1.760191488945417 0.508412420236076 0.6575551447589072 0.05300802197412029 186.0496413012269 0.9256623962969245 22.606344198329634 2.859947994011404 3.0000000156296288e-15 14.522878743017717 -1.251779068709341 RMS(ph)DEFVDSFKK ddPTM_PC-9_AZD4547_30min_R2 1 RMSDEFVDSFKK 12 2 Q92934;F5H1R6;F5H3B1 Q92934 BAD Bcl2-associated agonist of cell death 1 RMS(1)DEFVDSFKK 55.18600000000001 0.026136000000000003 5087500.0 46449.0 36944.0 50335.0 62075.0 50232.0 48640.0 36631.0 40519.0 41843.0 48248.0 True False 61218.81580078109 48885.42552070415 49667.52501169528 47764.567799189696 43258.15386743495 45598.53311084395 39891.08803635011 34257.7195839916 44054.73555582244 46558.852205548275 1.3148695232114385 1.0499705900155034 1.0667686736009474 1.0258965918729788 0.9291069650183518 0.9793740814214082 0.8567884762330205 0.7357939030101179 0.9462161000303304 1.0 15.506767872121793 -1.5228787453398234 0.4146481826933025 0.8756970517718751 8.299873097302186 0.7007416068493275 0.07823325818203185 41.68390563216751 0.5393795805260545 0.05479408766594232 255.67904513776298 0.029999999995890866 1.5228787453398234 7.42417604553031 RMS(ph)DPPLSTMPTAPGLR ddPTM_PC-9_Lapatinib_30min_R1 2 RMSDPPLSTMPTAPGLR 17 1 P78314;P78314-3;P78314-4 P78314 SH3BP2 SH3 domain-binding protein 2 1 RMS(0.999)DPPLSTMPTAPGLR;RMS(0.986)DPPLS(0.006)T(0.008)MPTAPGLR 67.214 0.020708 2085300.0 40430.0 38422.0 35543.0 30713.0 36400.0 31144.0 28424.0 25106.0 33412.0 33023.0 True False 39853.46078604606 38333.03621964064 32620.79173994764 32971.73647556453 34259.02356515346 29812.043720209913 29895.65564029987 26272.516413959074 29648.78871604205 38730.981549618424 1.028981430150166 0.9897254003369893 0.8422402540497717 0.8513013395574368 0.8845379640395656 0.7697208417508753 0.7718796282505884 0.6783333487250056 0.7655057406190149 1.0 15.241200443240086 -4.912410033704949 0.697126287050525 0.7836911143725673 1.1727637083402487 0.4477439355309262 0.08268321344808917 2.1913237047612273 0.9098182328119496 0.03610055739231265 0.6561117872354201 1.223460538829349e-05 4.912410033704949 0.38907259396768135 RMS(ph)GEPIQTVESIR ddPTM_PC-9_AZD4547_30min_R2 2 RMSGEPIQTVESIR 14 1 Q5VT52-2;Q5VT52-3;Q5VT52 Q5VT52-2 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 RMS(0.991)GEPIQT(0.009)VESIR;RMS(1)GEPIQTVESIR 74.77199999999999 0.0278 11353000.0 26260.0 23442.8 29650.9 40613.8 30684.1 31932.3 31330.3 35224.4 26317.8 27214.1 True False 34610.13375806826 31020.226651060068 29257.709692446104 31250.915886954994 26424.142361119633 29935.56823304694 34118.63600516664 29781.278356187337 27708.90517914644 26261.342642327363 1.3179118154562488 1.1812125173319379 1.1140980143676764 1.1899968829691732 1.0061992153641783 1.1399100434719416 1.2991961785752375 1.1340348725425269 1.0551214214952565 1.0 14.680653057162969 -1.5228787690668595 0.018403261362664812 1.5759888075976944e-08 2.585780411698997 0.32899346122097917 0.0845217171293247 5375.056444599647 7.65678581839613 408.83737403986356 703.8935568988571 0.02999999835688532 1.5228787690668595 2.585780395939109 RMS(ph)GEPIQTVESIR ddPTM_PC-9_Lapatinib_30min_R1 1 RMSGEPIQTVESIR 14 1 Q5VT52-2;Q5VT52-3;Q5VT52 Q5VT52-2 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 RMS(1)GEPIQTVESIR 59.251999999999995 0.027637000000000002 2595200.0 5089.5 4670.1 6305.2 4534.8 5346.5 8082.2 6560.5 8139.5 6708.1 6769.5 True False 5016.922796700011 4659.286670380091 5786.81079477585 4868.304319649335 5032.0293816234325 7736.543146528403 6900.170589226965 8517.690884705642 5952.563138575417 7939.599055208242 0.631886164756518 0.5868415568571662 0.7288542852777685 0.6131675272009877 0.6337888533958785 0.9744249165143122 0.8690830029635527 1.0728112119362225 0.7497309495333566 1.0 12.954850438671636 -6.757300413805147 24.99980647112096 0.9337527971190266 0.6395820950456137 0.7428188943195109 0.08658406924634716 50.554427079783714 305354.32109304843 0.027159300914343862 0.026231871337988242 1.7486366886068284e-07 6.757300413805147 -0.2941707020734129 RNALFPEVFS(ph)PTPDENSDQNSR ddPTM_PC-9_AZD4547_30min_R2 2 RNALFPEVFSPTPDENSDQNSR 22 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 RNALFPEVFS(0.995)PT(0.005)PDENSDQNSR;RNALFPEVFS(0.99)PT(0.01)PDENSDQNSR 135.17 1.341e-05 22318000.0 57350.0 45922.0 59483.0 85251.0 66576.0 64936.0 58895.0 66557.0 62509.0 63323.0 True False 75586.1070458955 60765.38844634512 58694.21655449824 65597.69906482035 57333.071585410704 60875.5416547238 64136.540905267124 56272.14497770755 65813.09812534739 61106.081044021106 1.2369653846962123 0.9944245713052593 0.9605298777418675 1.0735052542080625 0.938254762960624 0.996227226728364 1.0495934252282169 0.9208927166703561 1.0770302562511793 1.0 15.899028338243305 -4.760759491552026 24.974669538619214 0.9990742833452263 1.2369656614597386 0.662295176587963 0.05049446931216432 9.113522787248701 334527.63000833505 0.011568523970516704 0.06716898711628681 1.734764429008107e-05 4.760759491552026 0.23789137811451233 RNALFPEVFS(ph)PTPDENSDQNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RNALFPEVFSPTPDENSDQNSR 22 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 RNALFPEVFS(0.998)PT(0.002)PDENSDQNSR;RNALFPEVFS(0.959)PT(0.033)PDENS(0.007)DQNSR 152.03 9.2612e-06 11963500.0 28857.0 18956.7 24219.0 29987.9 35010.4 32934.0 31806.8 41702.0 30113.2 25580.8 True False 33741.92014827018 20838.595895534218 24796.47281106897 28307.775185083567 28150.363444259296 31206.883063006517 28793.829642709596 40607.36668692134 30553.54858142265 30218.396542498605 1.1166019381874268 0.6895996571567652 0.8205753993662654 0.936772907366942 0.9315637712500442 1.0327114153498422 0.9528576277108044 1.3437962080420738 1.0110909934765298 1.0 14.883139489371882 -6.897780550499912 1.2076996309715091 1.115738241648471 0.8690228696804473 0.2718391295592 0.14014426365697472 0.5218327353908672 1.5853009023307052 0.07400096114944625 0.05867301989387763 1.2653755816881883e-07 6.897780550499912 -0.24671537196802362 RNALFPEVFS(ph)PTPDENSDQNSR ddPTM_PC-9_Lapatinib_30min_R1 2 RNALFPEVFSPTPDENSDQNSR 22 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 RNALFPEVFS(0.988)PT(0.012)PDENSDQNSR;RNALFPEVFS(0.984)PT(0.016)PDENSDQNSR 149.44 6.378899999999999e-07 12456900.0 65546.0 61772.0 69314.0 66460.0 74983.0 73146.0 71338.0 58222.0 83166.0 72048.0 True False 64611.30202033575 61628.97072926035 63615.27047977756 71347.6901040607 70572.64736224996 70017.71609165418 75031.53258048517 60927.20666986076 73798.969303195 84501.40080207436 0.7646181176531414 0.7293248412959736 0.7528309575456874 0.8443373651423449 0.8351654137373486 0.8285982886325757 0.8879324113955195 0.7210200788572619 0.8733461055403399 1.0 16.366687637079835 -14.52287874527833 0.11640633214964165 1.6181728955137125 0.7048412143919632 0.6161870589471887 0.05041304427152827 115.42719805614702 0.8759362776197384 16.969615854879724 0.5608110276324065 3.000000000013867e-15 14.52287874527833 -0.9133316811217492 RNAYS(ph)Y(ph)S(ph)YY(ph)LSQRK ddPTM_PC-9_Lapatinib_30min_R1 1 RNAYSYSYYLSQRK 14 2 O14522-1 O14522-1 4 RNAY(0.041)S(0.932)Y(0.893)S(0.911)Y(0.526)Y(0.678)LS(0.02)QRK 49.333 0.045385 0.0 17113.0 23274.0 19259.0 22342.0 25139.0 20156.0 19412.0 20866.0 19368.0 19173.0 True False 16868.96548186015 23220.110482950306 17675.59936188987 23985.10521072716 23660.373445175617 19293.974865930883 20417.05837635452 21835.51053507807 17186.57188591832 22487.027503583366 0.7501643104750966 1.0326002616063916 0.7860353868057135 1.0666196413423283 1.0521787924795873 0.8580046812704053 0.9079482992183385 0.9710269857409355 0.764288293914329 1.0 14.456805347500975 -4.74112471202858 24.543113158030252 0.9361850161330443 0.7501634788142079 0.2330117745518172 0.10200629848434808 1803.258074164992 2178459.2752538025 0.024683629196653085 0.9841729539333466 1.8149943940376105e-05 4.74112471202858 -0.18602153731883642 RNES(ph)PGAPPAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RNESPGAPPAGK 12 1 P49796-1;P49796-4;P49796-6;P49796;C9J582;H7BXY1;A0A087WUY2;P49796-2;P49796-7;P49796-8;P49796-9 P49796-1 RGS3 Regulator of G-protein signaling 3 1 RNES(1)PGAPPAGK 60.691 0.027011 2730400.0 18828.0 23948.0 21622.0 22931.0 27368.0 25757.0 23057.0 18172.0 21543.0 18467.0 True False 22015.208530049258 26325.399173181675 22137.550481891627 21646.250413305057 22005.436862831844 24406.257577392924 20872.874041775824 17695.004254825537 21858.02561964812 21814.920915308423 1.0091812212163596 1.2067611556046516 1.0147893988630874 0.9922681130654476 1.0087332861880662 1.1187873507378179 0.9568163974928038 0.8111422600853083 1.0019759276005191 1.0 14.413027623133257 -7.435462958393657 6.203123448329969 0.9212480997518201 1.0572443863848764 0.3388325820808209 0.07857666970412353 0.24320962227135332 14.05615382196723 0.03338365770354006 0.02218517232909554 3.6689098577126484e-08 7.435462958393657 0.1359962866330563 RNEVLDR ddPTM_PC-9_AZD4547_30min_R2 4 RNEVLDR 7 1 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 ;;; 116.25 0.004983100000000001 30164900.0 45333.6 48002.9 68978.0 94710.0 79563.0 73996.0 60225.0 74945.0 57998.0 70740.0 False True 59748.74180254234 63518.89867712779 68063.30665057548 72876.0727549135 68517.05080734838 69369.01842249211 65584.9083287157 63363.972314772174 61063.65587473629 68263.41413158018 0.8752674117262066 0.9304969504556692 0.9970685984058901 1.067571460965053 1.0037155580188137 1.0161961470134036 0.9607622056860272 0.928227413188503 0.8945297660769486 1.0 16.058824950850045 -10.517100155930624 17.492407177802843 0.9999999999996187 0.9683983784806629 0.030489940231851254 0.056060410583684675 0.0 0.0 0.05994173148702723 0.014538005311966194 3.040183825070912e-11 10.517100155930624 -0.03160162151895585 RNEVLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RNEVLDR 7 1 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 ;;; 107.01 0.0063093 22972100.0 43749.8 47743.1 52768.6 58912.4 61682.0 59891.2 47296.0 51195.3 51349.8 45105.4 False True 51155.77704206229 52482.71944484423 54026.8035500299 55611.72922457783 49595.854887941874 56750.40003956809 42815.78048661271 49851.47762090414 52100.693680722645 53282.65196585009 0.9600831631813117 0.9849869987417564 1.0139661138611635 1.0437117367998217 0.9308068021788563 1.0650821223376898 0.8035594871301488 0.9356042873551965 0.9778172023816497 1.0 15.701378269067602 -7.2298611834886435 24.994970293147166 0.9238788176359988 0.9986082822376886 0.24568503783671636 0.06022769402880438 899.1843042683491 711728.737996124 0.022368371021345285 0.01732486057217018 5.8903190155838924e-08 7.2298611834886435 0.07472946460168983 RNEVLDR ddPTM_PC-9_Lapatinib_30min_R1 4 RNEVLDR 7 1 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 ;;; 127.02 0.0028647 27566800.0 64631.0 56954.2 62078.0 56602.9 69951.0 61122.0 52400.0 56881.0 61301.0 46161.8 False True 63709.35008812619 56822.32604915563 56974.18646800973 60765.66608773911 65836.61970895733 58507.9545423411 55113.01560483089 59523.89891429956 54396.63585185244 54140.80562326789 1.1767344307995682 1.0495286391663021 1.0523335552939048 1.1223635368592315 1.2160258598121594 1.080662798951709 1.0179570652924526 1.0994276540413763 1.004725275614935 1.0 15.72442873477957 -7.7767427334289305 1.0036594795792237 1.0075570514444365 1.113452101816547 0.36295732550355586 0.055068634300500414 0.7024102569788787 1.2821693930721594 0.05187953830603965 0.020958127853383232 1.6720808251738678e-08 7.7767427334289305 0.10589505037211056 RNFS(ph)CGSVEFDEADLESLR ddPTM_PC-9_AZD4547_30min_R2 1 RNFSCGSVEFDEADLESLR 19 1 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 RNFS(0.858)CGS(0.142)VEFDEADLESLR 82.865 0.00078738 2855300.0 1434.9 1658.8 6042.1 6450.1 4231.4 4472.8 3465.8 4983.4 4085.4 4925.3 True False 1891.1683522258986 2194.9746603980066 5961.9778061619945 4963.129098051609 3643.9431492806257 4193.115108926458 3774.249485855757 4213.330037139706 4301.345903490598 4752.866746144646 0.39790056259413253 0.4618212076276893 1.2543961622736712 1.04423905889588 0.7666832132915279 0.882228628085936 0.7940995797783079 0.8864818355274546 0.9050003152265303 1.0 12.214582238717398 -5.144202672451493 7.48916861629733 0.9270851945641121 0.4161789226907375 0.70564193825205 0.1321362578649154 0.1468752597329075 8.473334656779645 0.03589951519461847 0.09648694522115082 7.174593959524648e-06 5.144202672451493 -0.5109062718733746 RNHSY(ph)HLRYHGS(ph)SY(ph)S(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 RNHSYHLRYHGSSYSR 16 2 Q14236 Q14236 DIAPH2-AS1 Early lymphoid activation gene protein 4 RNHS(0.484)Y(0.516)HLRY(0.204)HGS(0.417)S(0.417)Y(0.977)S(0.986)R 48.74100000000001 0.040511 0.0 6216.1 6855.6 8907.7 12120.0 12011.0 7521.5 7955.0 11917.0 9570.9 8690.2 True False 8192.690497087891 9071.538631435127 8789.578077812212 9325.921252133372 10343.479974951453 7051.179415978886 8662.979589123015 10075.501475417164 10076.79823462039 8385.958743091021 0.9769533512000212 1.0817533104260664 1.0481303744850547 1.112087661988173 1.2334284357734508 0.840831636786691 1.0330338908786338 1.201472817132342 1.2016274517117567 1.0 13.033760017149705 -7.749379832883778 24.765597304173024 1.1511626053747945 1.0498033495559147 0.1164111515618601 0.10761346873376465 371.226938766722 762359.0257792504 0.05181188548917996 0.02961816155316348 1.7808205848604808e-08 7.749379832883778 -0.10135925581887983 RNIS(ph)PESSDNSH ddPTM_PC-9_AZD4547_30min_R2 1 RNISPESSDNSH 12 1 A0A3B3ISF0;Q659C4;Q659C4-2;Q659C4-8 A0A3B3ISF0 LARP1B La-related protein 1B 1 RNIS(0.968)PES(0.027)S(0.004)DNS(0.001)H 111.66 0.00082505 0.0 2239.8 2242.9 4801.2 6184.6 5755.4 5299.4 3416.9 6159.0 3350.8 4940.8 True False 2952.00980926585 2967.8735626999583 4737.5329509516505 4758.836021117494 4956.362055435481 4968.02768025507 3720.997480587609 5207.268069740231 3527.916447206219 4767.8240958624765 0.6191524162620864 0.6224796685086353 0.9936467570317636 0.998114847661267 1.039543816169019 1.0419905559364764 0.7804393378976995 1.0921686633236123 0.7399426606924843 1.0 12.219115294642483 -5.258265178994923 24.477829639558912 0.9646356176684276 0.6208159841983586 0.6153277154124712 0.1074679407081018 120.444961113723 928794.2611395188 0.02627468902873987 0.06373295398594296 5.51740445236052e-06 5.258265178994923 -0.34381963347006905 RNLEVLR ddPTM_PC-9_AZD4547_30min_R2 2 RNLEVLR 7 1 Q8N201 Q8N201 INTS1 Integrator complex subunit 1 0 ; 157.33 0.00029296 37313000.0 33031.0 31517.0 48684.0 67575.0 54185.0 45460.0 42276.0 57539.0 35641.0 51733.0 False True 43534.17091251912 41704.25390147336 48038.41835043951 51996.627773342676 46662.34805118179 42617.37901354785 46038.48210053606 48647.66966468308 37524.91049745642 49921.84341629967 0.8720465418211109 0.8353909040117049 0.9622725256726955 1.0415606519122564 0.9347080327555845 0.8536819976409988 0.9222111795155449 0.97447662857737 0.7516731740960589 1.0 15.607383587757043 -6.709713144841109 0.004299929018598846 1.830837015510859 7.256941704508358e-06 0.022525552373350632 0.08157177986276809 111933.48518084594 181.7337096178347 38214.97676783206 39158.006802746706 1.9511329139440067e-07 6.709713144841109 -1.8308297585691546 RNLEVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RNLEVLR 7 1 Q8N201 Q8N201 INTS1 Integrator complex subunit 1 0 ;;; 157.33 0.00029296 49529000.0 99197.0 102268.0 114856.0 127725.0 137955.0 126794.0 114568.0 110430.0 100196.0 93753.0 False True 115989.09286994368 112420.49117433383 117594.60263380548 120568.98234003712 110923.70806825353 120144.69943191974 103715.28963950949 107531.3295102569 101661.1769477913 110749.67675166053 1.0473086357627188 1.0150864045086094 1.0618053802314356 1.0886621602552837 1.001571393449601 1.0848311521606164 0.9364839038950461 0.9709403464118428 0.9179365568330388 1.0 16.756942962386795 -7.2685198842357535 24.99648595458805 0.9539185596979419 1.048405487604968 0.6674552313525814 0.03231671008640561 324.4494426371855 1145406.2244131584 0.012732481676383838 0.008786666714186073 5.388651727884915e-08 7.2685198842357535 0.09448692790702606 RNLEVLR ddPTM_PC-9_Lapatinib_30min_R1 4 RNLEVLR 7 1 Q8N201 Q8N201 INTS1 Integrator complex subunit 1 0 ;;; 176.66 7.9675e-05 65483200.0 88104.0 76673.0 86833.0 76416.0 82999.0 80149.0 77159.0 69075.0 88759.0 68450.0 False True 86847.62080370505 76495.4683792751 79693.92592507323 82035.88755630322 78117.1620023123 76721.2141064445 81153.91547811353 72284.47667068534 78762.02674629405 80281.49129610835 1.0817888332863468 0.9528406503702208 0.9926811851455529 1.0218530601745301 0.9730407437772526 0.9556525777961423 1.0108670649725147 0.9003878167144778 0.9810732894309357 1.0 16.29277979577062 -4.753860776947403 24.971834978787946 0.9756147368455427 1.0817890250733897 0.47825594911702707 0.03298374585771968 239.46953978430872 788996.8894563111 0.008213737439972372 0.08451002433289789 1.7625409787736802e-05 4.753860776947403 0.10617428822784702 RNPNPS(ph)SSSIFGR ddPTM_PC-9_AZD4547_30min_R2 1 RNPNPSSSSIFGR 13 1 Q9ULJ8-3 Q9ULJ8-3 PPP1R9A Neurabin-1 1 RNPNPS(0.423)S(0.127)S(0.423)S(0.026)IFGR 58.723 0.029457999999999998 6720500.0 25578.0 15893.0 33153.0 28250.0 26662.0 27537.0 28967.0 38013.0 23670.0 25845.0 True False 33711.27194454948 21030.101445445824 32713.369558214632 21737.398958149155 22960.44151961999 25815.10703686905 31545.006883485377 32138.96430184045 24921.14787673728 24940.17441660574 1.3516854927086535 0.8432219075197606 1.3116736479771096 0.8715816736099447 0.9206207276695068 1.0350812550725692 1.2648270359521618 1.2886423232245556 0.9992371127983856 1.0 14.606183934095231 -7.221235551191637 23.368889894260093 1.1622302186540594 1.0431223065018334 0.03803022300452463 0.181983585824821 611.0133571406723 355157.49030554405 0.0669930554655627 0.05189127221049287 6.008477632863481e-08 7.221235551191637 -0.11910791215222605 RNPNPS(ph)SSSIFGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RNPNPSSSSIFGR 13 1 Q9ULJ8-3 Q9ULJ8-3 PPP1R9A Neurabin-1 1 RNPNPS(0.421)S(0.153)S(0.421)S(0.005)IFGR 57.788000000000004 0.031169 12506000.0 45366.0 37031.0 39499.0 54243.0 65273.0 68795.0 53104.0 49118.0 56818.0 31707.0 True False 53045.567780657235 40707.19295064687 40440.805960791695 51203.940568178776 52483.22421615112 65187.26909332405 48073.604680334116 47828.704544822845 57648.85576090456 37455.22810752609 1.4162393465706458 1.0868227216180628 1.0797105772442404 1.3670705841433677 1.40122559300621 1.7404050752590559 1.2834951783586765 1.2769567016790468 1.5391404264154207 1.0 15.192879487776073 -5.877730718902787 6.602072605523721 1.3995180218990193 1.1845867287513012 0.13526054467656845 0.19955830579209718 0.3530921581510663 18.99397278064491 0.05545072636292174 0.08296916276944707 1.3251629380428432e-06 5.877730718902787 -0.21493129314771808 RNPNPSSS(ph)SIFGR ddPTM_PC-9_AZD4547_30min_R2 1 RNPNPSSSSIFGR 13 1 Q9ULJ8-3 Q9ULJ8-3 PPP1R9A Neurabin-1 1 RNPNPS(0.133)S(0.221)S(0.636)S(0.009)IFGR 66.67399999999999 0.016913 10548000.0 27742.0 18188.0 41839.0 40609.0 36833.0 32237.0 45023.0 53737.0 22993.0 36900.0 True False 36563.3789305533 24066.915314274775 41284.187522883054 31247.22245279571 31719.37373385954 30221.215293879053 49029.959778891935 45433.18140341461 24208.363038860163 35608.14223148589 1.0268263559737965 0.6758823630229723 1.1594030167172895 0.8775302639957974 0.8907899077591368 0.8487164283217354 1.3769311372705662 1.275921139273621 0.6798547051818484 1.0 15.119919548096886 RNPNPSSS(ph)SIFGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RNPNPSSSSIFGR 13 1 Q9ULJ8-3 Q9ULJ8-3 PPP1R9A Neurabin-1 1 RNPNPS(0.197)S(0.197)S(0.577)S(0.028)IFGR 53.924 0.038449000000000004 14208000.0 18605.0 29499.0 29066.0 31033.0 42117.0 28824.0 40195.0 26993.0 22526.0 21781.0 True False 21754.45903450002 32427.465767900736 29759.043673418848 29294.32162034348 33864.476189414236 27312.41869824801 36387.43861340065 26284.462351447586 22855.400134994823 25729.722881698886 0.8454991580952315 1.2603115049857703 1.1566017951396572 1.1385401138999454 1.316161714804222 1.0615123537795608 1.4142180535991087 1.021560258239053 0.8882878467086592 1.0 14.651148298364197 -7.987096874440522 24.994828217966635 0.9477372216937328 1.1766943020253804 0.29162729451194924 0.1462678057782196 243.297940252449 471295.78830867104 0.07554796836768454 0.036258554281960675 1.0301563064533347e-08 7.987096874440522 0.22895708033164763 RNPS(ph)PDHSYKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RNPSPDHSYKR 11 2 Q15696 Q15696 ZRSR2 U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 1 RNPS(0.992)PDHS(0.005)Y(0.004)KR 50.108000000000004 0.035988 1881600.0 8044.2 7167.1 7977.6 7935.4 9669.4 9627.2 7168.8 10381.0 7588.2 7783.0 True False 9405.924179807846 7878.602322286221 8167.816239216483 7490.805264913916 7774.750482368687 9122.332684283001 6489.71936638255 10108.509749578685 7699.163069535996 9193.9962898059 1.0230506825673757 0.8569290299825161 0.8883858533065515 0.8147496506192368 0.8456334152526425 0.9922053910765269 0.7058649102978437 1.0994685478377642 0.8374120270281877 1.0 13.166476368624101 RNPS(ph)PDHSYKR ddPTM_PC-9_Lapatinib_30min_R1 1 RNPSPDHSYKR 11 2 Q15696 Q15696 ZRSR2 U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 1 RNPS(1)PDHSYKR 58.699 0.022688 6187000.0 7881.1 4947.2 7016.3 5191.3 5293.9 5772.3 5082.2 4846.8 6462.7 4529.7 True False 7768.71406878327 4935.745062355061 6439.446897701228 5573.085519669139 4982.523210207854 5525.432184888513 5345.33144860442 5072.00002211331 5734.802670751973 5312.652609554142 1.4623041707662587 0.9290547350072806 1.2120963614524103 1.0490212572240543 0.937859780488453 1.0400514754064125 1.0061511341794698 0.9547019906763621 1.0794612582871779 1.0 12.375216663789844 -4.753610172896153 24.998729626214253 1.0257836204899373 1.4623049583302872 0.738217060364013 0.07843930826976755 146.7668838063867 468590.4478802464 0.019402254079375056 0.205695611274408 1.763558323896243e-05 4.753610172896153 0.43652133784034985 RNQEIQQGEDAFPPS(ph)SPLFAEPYK ddPTM_PC-9_Lapatinib_30min_R1 2 RNQEIQQGEDAFPPSSPLFAEPYK 24 1 Q9UHB7;Q9UHB7-2;Q9UHB7-3;C9JCE0 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 RNQEIQQGEDAFPPS(0.482)S(0.482)PLFAEPY(0.036)K;RNQEIQQGEDAFPPS(0.498)S(0.498)PLFAEPY(0.004)K 65.425 0.00059968 5283600.0 14285.4 18535.7 17088.0 15471.3 21483.7 17756.6 18822.3 18237.9 18080.9 17087.2 True False 14081.687576378483 18492.781725480007 15683.090601587535 16609.111012743837 20220.071004579306 16997.191610656293 19796.82659577878 19085.299414727328 16044.438641682169 20040.69975273718 0.7026544856276883 0.9227612784805204 0.7825620260313277 0.8287690159359504 1.0089503487430687 0.8481336390629174 0.9878311057015318 0.9523269970710797 0.8005927357646683 1.0 14.290645262941798 -6.110813415656328 7.569752299538377 0.9288944445792563 0.8132418784365056 0.3665688990593543 0.0797819689826252 0.31654774569767496 19.331758534889644 0.022385317358007407 0.029006673382867786 7.747945984659809e-07 6.110813415656328 -0.11565256614275066 RNQNY(ph)MNILR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RNQNYMNILR 10 1 H0Y5Q9;Q92835-3;Q92835-2;Q92835 H0Y5Q9 INPP5D Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 1 RNQNY(1)MNILR 62.464 0.018221 5974200.0 4099.9 6145.2 4719.4 1493.1 2300.7 3844.3 4516.0 5023.0 4498.8 2453.4 True False 4793.932093283885 6755.254843788044 4831.928394424169 1409.4464476955118 1849.8943507131398 3642.6981404966273 4088.211786991353 4891.151572308421 4564.586439106575 2898.1819988962848 1.6541169930354818 2.3308594306225934 1.6672273847067967 0.4863208895204896 0.6382947487140681 1.2568907480219933 1.4106125110666852 1.6876619805695845 1.574982675637661 1.0 11.500932480198957 -5.530310849366975 24.996364291620154 1.1658191140018288 1.9941271064995196 0.44338896164665764 0.3878716223586539 164.61441505854154 553645.2951931374 0.11735848577525114 0.20378790404793728 2.9490976334381206e-06 5.530310849366975 0.8283079924976908 RNS(ph)APESILLVPPTWPK ddPTM_PC-9_AZD4547_30min_R2 2 RNSAPESILLVPPTWPK 17 1 Q13469-3;Q13469-4;Q13469-2;Q13469;Q13469-5 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 RNS(0.923)APES(0.077)ILLVPPTWPK;RNS(0.996)APES(0.004)ILLVPPTWPK 130.49 1.2857e-05 16154200.0 64607.0 75783.0 74738.0 64900.0 73378.0 77565.0 79251.0 105538.0 92428.0 76609.0 True False 85150.68209091833 100278.37273266351 73746.92528705836 49938.30769500457 63190.73129647721 72714.84828829402 86304.18547046997 89229.52712197501 97313.55538449828 73926.94222796474 1.1518220492380642 1.3564523259117118 0.9975649345762027 0.6755089036553461 0.8547726903355367 0.9836041650967646 1.1674253373599324 1.206996048163638 1.316347632564288 1.0 16.173812621254463 -7.307173745019378 5.093703051830433 1.1929194198896842 0.9972575426747724 0.1695993711099163 0.18162338423410415 0.3981470432383643 24.755723846093492 0.08764244421103635 0.05927873710565063 4.929765429765078e-08 7.307173745019378 -0.1956618772149118 RNS(ph)APESILLVPPTWPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RNSAPESILLVPPTWPK 17 1 Q13469-3;Q13469-4;Q13469-2;Q13469;Q13469-5 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 RNS(0.811)APES(0.189)ILLVPPTWPK 141.83 4.7088e-05 7059700.0 71343.0 90246.0 67534.0 71991.0 85830.0 45153.0 53701.0 48614.0 47461.0 47393.0 True False 83419.96081152034 99205.02646496407 69144.26668412138 67957.57766797103 69012.22763581027 42785.09719268635 48614.05251842842 47337.93401079072 48155.02733760943 55984.97573721841 1.4900419213018137 1.7719937386525164 1.235050400105019 1.213853837982345 1.2326919272009513 0.7642246268625803 0.8683410482593127 0.8455471023687664 0.8601419702964399 1.0 15.772752093548565 -5.894122746244134 0.8529975522469906 0.8552916423569165 1.6708163167658967 0.8044350776464343 0.13581919631482287 0.29880379182938765 0.4191995518472149 0.06169508999805513 0.16842803324676126 1.2760780952010784e-06 5.894122746244134 0.8155246744089802 RNS(ph)APESILLVPPTWPK ddPTM_PC-9_Lapatinib_30min_R1 1 RNSAPESILLVPPTWPK 17 1 Q13469-3;Q13469-4;Q13469-2;Q13469;Q13469-5 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 RNS(0.881)APES(0.119)ILLVPPTWPK 119.46 4.5258e-05 9210700.0 19976.0 42163.0 37250.0 34593.0 40767.0 36991.0 41690.0 38872.0 33426.0 39069.0 True False 19691.138576850255 42065.37416398702 34187.44878915822 37137.08461886511 38369.165211005806 35408.98116023265 43848.50420926332 40678.135029212805 29661.211888615537 45822.02459382981 0.42973087181097136 0.9180164895998802 0.7460920614529492 0.8104636350761731 0.8373520277882358 0.7727502543613202 0.9569307466865566 0.8877419841176188 0.6473134295469254 1.0 15.483753583433186 -4.754290818365616 24.996377008355402 0.8356660235973408 0.42973016507154194 0.605659828682088 0.09964985369105842 167.60079827565934 585999.3705038332 0.023572445112867716 0.23324518204350062 1.760796562240297e-05 4.754290818365616 -0.40593585852579883 RNS(ph)CNVGGGGGGFK ddPTM_PC-9_AZD4547_30min_R2 4 RNSCNVGGGGGGFK 14 1 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 RNS(1)CNVGGGGGGFK;RNS(1)CNVGGGGGGFK;RNS(1)CNVGGGGGGFK;RNS(1)CNVGGGGGGFK 154.47 0.00013575 99627700.0 158370.0 187684.0 162374.4 162743.1 164334.6 186644.0 150632.3 191911.0 167303.7 148557.9 True False 208728.36569936262 248349.18263934128 160221.20936245195 125225.19265083064 141519.57741167722 174973.12117476037 164038.282886569 162255.564626062 176147.03202472682 143356.93313850535 1.4560046809713638 1.7323834794888986 1.1176383719624712 0.8735203098258485 0.98718334937416 1.2205417439120911 1.1442647334543787 1.1318292117012407 1.2287304713371698 1.0 17.129252153432155 -5.274606256801641 22.714267491945932 1.0881593269580536 1.594194014583098 0.7381680050160521 0.12059850571282232 100.31615107960921 173056.9827797117 0.0330162978501948 0.06958817520479735 5.313659767705467e-06 5.274606256801641 0.5060346876250443 RNS(ph)CNVGGGGGGFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RNSCNVGGGGGGFK 14 1 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 RNS(1)CNVGGGGGGFK;RNS(1)CNVGGGGGGFK;RNS(1)CNVGGGGGGFK 86.22200000000001 0.0030194 41592000.0 165097.0 232903.0 140383.0 143344.0 214528.0 199134.0 284771.0 254041.0 237174.0 211385.0 True False 193044.66128561422 256024.07063769526 143730.26312549197 135312.9004075182 172492.77840213355 188691.06248462808 257795.42931650067 247372.69292868886 240642.22106087478 249707.4271772603 0.7730833778867827 1.0252961777382414 0.5755946659266241 0.5418857658225094 0.6907795268728061 0.755648578889412 1.0323899141914545 0.9906501209236597 0.9636966900870337 1.0 17.92987920716648 -7.20722936370306 5.2525630260637115 0.9960656859354967 0.7213902309446978 0.5340750235828122 0.12349487935952812 0.18754379591267273 11.510663041794778 0.05381218505101062 0.04079135499448287 6.205412215838786e-08 7.20722936370306 -0.27467545499079893 RNS(ph)CNVGGGGGGFK ddPTM_PC-9_Lapatinib_30min_R1 2 RNSCNVGGGGGGFK 14 1 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 RNS(1)CNVGGGGGGFK;RNS(1)CNVGGGGGGFK 132.9 5.422000000000001e-06 62443000.0 30080.0 60439.0 66470.0 50731.0 119024.0 129666.0 176348.0 185174.0 152272.0 157367.0 True False 29651.05368400358 60299.05720886109 61005.09318162009 54461.92697365495 112023.24233018738 124120.4874462091 185478.43656260922 193777.86005092188 135121.52386475395 184567.6762716531 0.16065138968516965 0.32670432020886936 0.33052967027569163 0.2950783586476757 0.6069494106070215 0.6724930927966187 1.0049345600993298 1.0499013909982424 0.73209744303156 1.0 17.49379038730217 -6.65392570439944 1.2613181525529216 0.9539528217278802 0.26367038530944964 0.8926514057476065 0.102527511496662 0.13159970582120892 0.44028965409383486 0.04749779591969154 0.047322728396678906 2.2185759234304964e-07 6.65392570439944 -0.6902824364184306 down RNS(ph)EGSELSCTEGSLTSSLDSR ddPTM_PC-9_AZD4547_30min_R2 1 RNSEGSELSCTEGSLTSSLDSR 22 1 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 RNS(0.76)EGS(0.24)ELSCTEGSLTSSLDSR 109.83 8.950900000000001e-06 4444600.0 5387.2 5009.0 7484.1 10076.0 6036.8 7554.9 4094.4 9161.3 8263.6 7070.3 True False 7100.217539278951 6628.061293666275 7384.855943975929 7753.133872648176 5198.694522753056 7082.49090869891 4458.793668096196 7745.631590730829 8700.397025526234 6822.770949031829 1.040664796212526 0.9714617921633167 1.0823836823986976 1.1363614476532249 0.7619623407540547 1.0380666391422588 0.6535165406261969 1.1352618530789103 1.275199928375266 1.0 12.736142068271098 -7.965923425387283 24.999532257301055 1.1601447829021563 0.958295179449345 0.22863438465757402 0.15190384850941788 234.67287238466085 172162.45966195315 0.08206005152780776 0.03942005335060237 1.0816246460694017e-08 7.965923425387283 -0.20184960345281133 RNS(ph)EGSELSCTEGSLTSSLDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RNSEGSELSCTEGSLTSSLDSR 22 1 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 RNS(0.91)EGS(0.089)ELS(0.001)CTEGSLTSSLDSR;RNS(0.941)EGS(0.059)ELSCTEGSLTSSLDSR 123.61 2.2331999999999996e-07 23049800.0 12181.7 12801.31 15592.91 16324.5 19992.51 12831.35 15516.5 15524.53 13746.47 13108.3 True False 14243.821210457883 14072.13945588953 15964.704110840474 15409.891189743083 16075.121182933868 12158.45141769929 14046.66479026823 15117.027537099195 13947.486117983766 15484.731024754303 0.9198623590998986 0.9087751949577576 1.0309965400961032 0.9951668624471695 1.0381272465912228 0.7851897070903244 0.9071300475166704 0.9762538020797851 0.9007251140292294 1.0 13.918558702657386 RNS(ph)EGSELSCTEGSLTSSLDSR ddPTM_PC-9_Lapatinib_30min_R1 3 RNSEGSELSCTEGSLTSSLDSR 22 1 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 RNS(0.902)EGS(0.098)ELSCTEGSLTSSLDSR;RNS(0.938)EGS(0.062)ELSCTEGSLTSSLDSR;RNS(0.995)EGS(0.005)ELSCTEGSLTSSLDSR 157.73 2.2913e-06 29102600.0 10011.7 9860.4 15307.1 13428.2 14453.800000000001 13307.9 13596.5 13756.4 13314.5 11331.400000000001 True False 9868.931322079075 9837.568849621171 14048.609325114727 14415.75462316204 13603.655901264145 12738.752139230088 14300.460241814553 14395.572564207212 11814.880802099313 13290.017391858579 0.7425822729265013 0.7402224210517312 1.0570798299873452 1.0847054746514542 1.0235995559793398 0.9585203513002026 1.0760302127651817 1.0831868868001553 0.8890041640831162 1.0 13.69805537213432 -5.25784132168994 24.968451800195034 1.02651507126632 0.7414023106466132 0.785485173113985 0.05850695779719956 123.37462459175242 856139.696301707 0.014983579116011997 0.03653073907944502 5.522791888410292e-06 5.25784132168994 -0.2851127606197068 RNS(ph)FSENEK ddPTM_PC-9_AZD4547_30min_R2 5 RNSFSENEK 9 1 Q9HCG8 Q9HCG8 CWC22 Pre-mRNA-splicing factor CWC22 homolog 1 RNS(0.996)FS(0.004)ENEK;RNS(0.991)FS(0.009)ENEK;RNS(1)FSENEK;RNS(0.996)FS(0.004)ENEK;RNS(1)FSENEK 108.72 0.0035505000000000003 628033300.0 177424.0 164165.8 246100.0 269452.0 232253.0 224659.0 201758.0 250831.0 208096.0 207281.0 True False 233841.14135154185 217229.18441280868 242836.55320111677 207334.00439190125 200008.679928599 210611.037215236 219714.07114296374 212070.83247296797 219095.5297235963 200024.155281426 1.1690645113463256 1.0860147571035903 1.2140361390825793 1.0365448317988923 0.999922632580024 1.0529280172132944 1.0984376903571211 1.0602261120642793 1.0953453567412277 1.0 17.60981470743903 -5.780861610168298 24.9998874180674 1.051738664417753 1.1493361124758488 0.5667794257646859 0.042817459780274285 182.34613081972373 234711.64552756332 0.012105124342902084 0.01798529927417843 1.656297665866209e-06 5.780861610168298 0.09759744805809567 RNS(ph)FSENEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RNSFSENEK 9 1 Q9HCG8 Q9HCG8 CWC22 Pre-mRNA-splicing factor CWC22 homolog 1 RNS(0.996)FS(0.004)ENEK;RNS(0.999)FS(0.001)ENEK;RNS(0.982)FS(0.018)ENEK;RNS(0.999)FS(0.001)ENEK;RNS(0.967)FS(0.033)ENEK 123.62 0.0006808 437373000.0 222188.0 235747.0 250227.0 273475.0 295925.0 276478.0 330835.0 302957.0 291550.0 261001.0 True False 259800.03998696484 259150.40416235404 256193.36067118196 258153.08236791258 237940.62056538722 261979.00696829768 299495.91376202006 295004.69975947554 295813.3671915896 308318.41521722154 0.8426354935819395 0.8405284646386534 0.8309375892798503 0.8372937509620836 0.7717366489372663 0.849702755457289 0.9713850972898077 0.9568182930352506 0.9594411251211782 1.0 18.23406153562739 -7.212222060494387 4.302083352722648 0.9691313507611439 0.8254752494123714 0.9092370530512737 0.022224852099411656 0.06258312966079875 2.515459650757146 0.009156343775635204 0.006795467482976942 6.134482607772989e-08 7.212222060494387 -0.1436561013487725 RNS(ph)FSENEK ddPTM_PC-9_Lapatinib_30min_R1 4 RNSFSENEK 9 1 Q9HCG8 Q9HCG8 CWC22 Pre-mRNA-splicing factor CWC22 homolog 1 RNS(0.997)FS(0.003)ENEK;RNS(0.989)FS(0.011)ENEK;RNS(0.997)FS(0.003)ENEK;RNS(0.998)FS(0.002)ENEK 98.40700000000001 0.0045092 398932200.0 183189.0 142369.0 168246.0 143865.0 173818.0 167718.0 168995.0 170914.0 194869.0 144728.0 True False 180576.69126725197 142039.35332762558 154413.46332834102 154445.3120195714 163594.36697933616 160545.09210975384 177744.7342011145 178855.2883922331 172920.80115845817 169744.0419620621 1.0638175524747489 0.8367855017813908 0.909684142921803 0.9098717706633263 0.9637708934484994 0.9458069352775031 1.047133861940442 1.0536763843069519 1.0187149967661668 1.0 17.37300141101204 -7.17496749320221 3.844698689175827 1.0345500578045514 0.9302279839056715 0.3922945256663709 0.0553468408811661 0.22515268502038727 6.214235079397945 0.021919610770119967 0.016423719788126023 6.683939447611982e-08 7.17496749320221 -0.10432207389887993 RNS(ph)FTPLSSSNTIR ddPTM_PC-9_AZD4547_30min_R2 4 RNSFTPLSSSNTIR 14 1 O60825 O60825 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2;6-phosphofructo-2-kinase;Fructose-2,6-bisphosphatase 1 RNS(0.777)FT(0.223)PLSSSNTIR;RNS(0.978)FT(0.022)PLSSSNTIR;RNS(0.993)FT(0.007)PLSSSNTIR;RNS(1)FTPLSSSNTIR 183.76 1.0399000000000002e-05 270939000.0 90322.0 73329.0 104720.0 150120.0 143741.0 105866.0 77873.0 121493.0 95689.0 93764.0 True False 119042.5171856907 97031.165223249 103331.3443771675 115512.15333087955 123785.04330026598 99246.1822843874 84803.5461400097 102719.04848140103 100746.92518703463 90481.35089954059 1.31565804447218 1.0723885558581074 1.1420181435166012 1.2766404588624025 1.3680724488486222 1.0968689271071803 0.9372488949039363 1.1352510485331688 1.1134551394893704 1.0 16.46533284868177 -6.98185325525833 24.89807940955009 1.0519452827751632 1.2240161235135 0.47829446401588305 0.09392085076786283 230.4850314907085 316233.8062542941 0.0349117560926958 0.030784111516343176 1.0426696798875824e-07 6.98185325525833 0.1720708407383369 RNS(ph)FTPLSSSNTIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RNSFTPLSSSNTIR 14 1 O60825 O60825 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2;6-phosphofructo-2-kinase;Fructose-2,6-bisphosphatase 1 RNS(0.958)FT(0.042)PLSSSNTIR;RNS(0.997)FT(0.003)PLSSSNTIR;RNS(1)FTPLSSSNTIR;RNS(1)FTPLSSSNTIR 152.11 0.00030205 161040000.0 88338.0 70024.0 75073.0 92356.0 112913.0 109397.0 106240.0 126441.0 101727.0 89606.0 True False 103291.87864496968 76975.51994750615 76863.02503593804 87181.59274219198 90788.5082027526 103660.02873758794 96176.17808900803 123122.05772531322 103214.5649264238 105850.85847929447 0.9758246662229446 0.7272073278703107 0.7261445598098125 0.8236266950942641 0.8577021434409223 0.9793026738452473 0.9086008320643056 1.163165414944624 0.9750942638468411 1.0 16.691673444479513 -6.868426634655228 1.2954094276208246 1.0363489083403408 0.7988681554708306 0.5292996739734571 0.08755056966714955 0.3208853749931171 1.1212253782297472 0.04421567833456245 0.03617857696120304 1.3538587786495068e-07 6.868426634655228 -0.2374807528695102 RNS(ph)FTPLSSSNTIR ddPTM_PC-9_Lapatinib_30min_R1 3 RNSFTPLSSSNTIR 14 1 O60825 O60825 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2;6-phosphofructo-2-kinase;Fructose-2,6-bisphosphatase 1 RNS(0.979)FT(0.021)PLSSSNTIR;RNS(0.981)FT(0.019)PLSSSNTIR;RNS(0.973)FT(0.027)PLSSSNTIR 139.21 8.201399999999999e-05 234340000.0 44621.0 65074.0 53778.0 40754.0 56531.0 58429.0 59321.0 53397.0 63197.0 45277.0 True False 43984.696357510766 64923.32515113463 49356.58042908321 43751.18511135864 53205.957724222244 55930.127874651494 62392.3511201178 55878.01955533228 56079.088366087344 53103.06912218974 0.8282891570033801 1.2225908261864595 0.9294487351665891 0.8238918359066498 1.0019375264694355 1.0532372007718935 1.1749292866021264 1.0522559332071257 1.0560423209635925 1.0 15.696507624371849 -6.724645540213405 3.7632827876483335 1.0787985258726418 0.9637650383299933 0.18883267929790037 0.11114830379051917 0.4002634489791486 11.913722202572911 0.03970938425354805 0.03799138487135671 1.8851871021214327e-07 6.724645540213405 -0.11503348754264853 RNS(ph)LDGGGR ddPTM_PC-9_AZD4547_30min_R2 1 RNSLDGGGR 9 1 O43896 O43896 KIF1C Kinesin-like protein KIF1C 1 RNS(1)LDGGGR 56.551 0.039548 27747000.0 18879.0 11909.0 14360.0 20102.0 16121.0 15603.0 12065.0 14312.0 17676.0 19091.0 True False 24882.12929240557 15758.351356812074 14169.577017342675 15467.794472804047 13882.877418715552 14627.341943431307 13138.76162699801 12100.40925704208 18610.317273730805 18422.62990084815 1.3506285164671323 0.8553801189962885 0.7691397533144998 0.8396083814337459 0.7535773933164887 0.7939877217398742 0.7131859944921936 0.6568231203778888 1.0101878707813596 1.0 14.169191405912706 -4.760835049739391 4.123749138876657 0.7992766398426129 1.4082261377113183 0.681686300228852 0.10823875610639742 0.12546750039016163 4.143078236127059 0.02565849521023178 0.23400367443922424 1.734462642410145e-05 4.760835049739391 0.6089494978687054 RNS(ph)LEGYSR ddPTM_PC-9_AZD4547_30min_R2 1 RNSLEGYSR 9 1 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 RNS(1)LEGYSR 87.641 0.0049207 13461000.0 12829.0 14711.0 20383.0 24223.0 22052.0 21528.0 17275.0 27374.0 18293.0 21232.0 True False 16908.355140223055 19466.043060715638 20112.708101984383 18638.761591619354 18990.46044522766 20181.850756789656 18812.441533890647 23143.97729194171 19259.93063410034 20488.674142517826 0.8252537486129988 0.9500879815507418 0.9816500551515316 0.909710480139876 0.9268760054033418 0.9850247320254143 0.9181873557572628 1.1295985836347326 0.9400281589784468 1.0 14.322539007631958 -7.697087245021784 24.99998872830561 1.0261163991355313 0.932450562118341 0.3401166102165708 0.060448678461265365 63.877962697297086 24815.27444718956 0.027068945806617076 0.01562825337341082 2.0086892483259003e-08 7.697087245021784 -0.09366583701719033 RNS(ph)LEGYSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RNSLEGYSR 9 1 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 RNS(1)LEGYSR 122.18 0.0023093000000000002 6541300.0 28805.0 35285.0 39381.0 41237.0 38464.0 38615.0 46744.0 38411.0 40679.0 30276.0 True False 33681.117575316995 38787.86160955886 40319.99239327421 38926.62458215783 30927.25531613434 36589.96142217759 42316.069922746625 37402.7519498186 41273.853417892875 35764.79913531585 0.941739318816939 1.0845261974715774 1.1273652688702045 1.088406073102193 0.8647400814169625 1.0230719116788478 1.1831765016390583 1.0457979033603844 1.154035655610243 1.0 15.126252718536254 RNS(ph)LEGYSR ddPTM_PC-9_Lapatinib_30min_R1 3 RNSLEGYSR 9 1 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 RNS(1)LEGYSR;RNS(1)LEGYSR;RNS(0.964)LEGYS(0.036)R 115.92 0.0008937999999999999 21718300.0 55246.4 60543.0 73432.0 65714.0 75193.0 84709.0 72113.0 71174.0 84733.0 73714.0 True False 54458.57620505105 60402.81640325086 67394.70441571712 70546.82677547775 70770.29557512581 81086.19353632368 75846.6582883811 74481.00387346145 75189.47726195358 86455.36668226901 0.6299039411305842 0.698658958040586 0.7795317630587181 0.8159912968126486 0.8185760848740923 0.9378965892808308 0.8772926563035024 0.8614965933483992 0.8696912655322074 1.0 16.39966790091365 -3.496927936998363 0.32392220845837244 0.9334100540887759 2.409781390958595e-22 0.8669622740331817 0.03746331359368434 5.859439099457237 0.25801912463919646 0.03767589933017434 2.5237186031564756 0.0003184725923258627 3.496927936998363 -0.9334100540887759 RNS(ph)LGGDVLFVGK ddPTM_PC-9_AZD4547_30min_R2 2 RNSLGGDVLFVGK 13 1 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 RNS(1)LGGDVLFVGK;RNS(1)LGGDVLFVGK 145.69 4.5518e-05 67526000.0 501470.0 446780.0 632400.0 784040.0 756030.0 596740.0 551140.0 647440.0 579620.0 660450.0 True False 660927.0287760275 591192.8977409104 624013.9627971812 603291.6912972477 651068.284527727 559425.7534655645 600190.3923003479 547393.0246911205 610257.5298823179 637327.8465253358 1.0370283244006246 0.9276119048681934 0.9791098352272839 0.9465955309913874 1.021559450253591 0.8777676301381028 0.9417294341876656 0.858887663037896 0.9575252881376465 1.0 19.281676171694542 -6.763173209239154 24.999920560016296 0.9192717010328003 0.9771684644499252 0.23919035095447005 0.047751087903814424 62.50790508480589 901284.0436978856 0.015320048790337472 0.014209282168795568 1.7251497150103858e-07 6.763173209239154 0.05789676341712491 RNS(ph)LGGDVLFVGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RNSLGGDVLFVGK 13 1 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 RNS(1)LGGDVLFVGK;RNS(1)LGGDVLFVGK;RNS(1)LGGDVLFVGK 146.76 3.4118e-05 36828000.0 236359.0 248960.0 243079.0 266628.0 310693.0 274895.0 285656.0 288673.0 252655.0 209807.0 True False 276369.91039695777 273675.1034806798 248874.92524224136 251689.69757963956 249814.93697836174 260479.02227500995 258596.5957096545 281095.6396243259 256349.60139870018 247843.34826870207 1.1150991637561656 1.1042261387784833 1.0041622136754742 1.0155192759370222 1.0079549793183158 1.0509825020303099 1.0433872747284474 1.1341665676642367 1.034321087047194 1.0 17.919069014065983 -5.15774184977176 6.676922731025553 1.0402177980110578 1.11176620858367 0.38517063054127276 0.03686243190308565 0.2771246937322783 15.274767622438269 0.010081939857271517 0.027336003413286826 6.954375717958978e-06 5.15774184977176 0.07154841057261208 RNS(ph)LGGDVLFVGK ddPTM_PC-9_Lapatinib_30min_R1 2 RNSLGGDVLFVGK 13 1 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 RNS(1)LGGDVLFVGK;RNS(1)LGGDVLFVGK 135.09 2.2658000000000002e-05 43079000.0 412340.0 372400.0 419990.0 366210.0 366500.0 360670.0 260910.0 287650.0 389430.0 325140.0 True False 406459.9559861049 371537.7306801877 385460.04340828274 393142.3050407487 344943.19056672376 345244.9848628341 274418.64315756527 301015.26911795256 345568.2925203001 381340.0157781828 1.0658728147285068 0.9742951573597856 1.0108040789312194 1.030949516898932 0.904555452599996 0.9053468573401844 0.7196166984930022 0.7893618730352353 0.9061946772491604 1.0 18.54071840213254 -6.530126683596598 1.996693165817062 0.8385997201405135 1.017511183856074 0.4846490128922817 0.07456995729358226 0.25838037545760867 2.0766400461920385 0.027410368494803796 0.029526765831876797 2.9503484851852935e-07 6.530126683596598 0.17891146371556044 RNS(ph)LPQIPMLNLEAR ddPTM_PC-9_AZD4547_30min_R2 3 RNSLPQIPMLNLEAR 15 1 H0YB74;Q14289-2;Q14289 H0YB74 PTK2B Protein-tyrosine kinase 2-beta 1 RNS(1)LPQIPMLNLEAR;RNS(1)LPQIPMLNLEAR;RNS(1)LPQIPMLNLEAR 125.59 1.1908e-05 29434800.0 43361.0 41799.0 48424.0 72279.0 61821.0 47588.0 49188.0 50297.0 40770.0 47005.0 True False 57148.89603517124 55309.70932600452 47781.86612032048 55616.193249418175 53238.22125813621 44612.314837147285 53565.63671021782 42524.75436007865 42925.01896639538 45359.36925720849 1.2599138165063695 1.2193668084838885 1.053406758135796 1.2261236026905218 1.1736984470893104 0.9835303172796548 1.1809167011665445 0.9375076209491303 0.9463319192775979 1.0 15.469112958634174 -7.0930155455175266 0.6508437699129107 0.9550762403754801 1.2061709044368627 0.5448020198263133 0.08079991659943489 0.6025531278842934 0.5285536894969526 0.06882561846557647 0.05427096873369859 8.072061358874234e-08 7.0930155455175266 0.2510946640613826 RNS(ph)LPQIPMLNLEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RNSLPQIPMLNLEAR 15 1 H0YB74;Q14289-2;Q14289 H0YB74 PTK2B Protein-tyrosine kinase 2-beta 1 RNS(1)LPQIPMLNLEAR;RNS(1)LPQIPMLNLEAR;RNS(1)LPQIPMLNLEAR;RNS(1)LPQIPMLNLEAR;RNS(1)LPQIPMLNLEAR 120.11 3.9749e-05 35658600.0 68581.1 84061.0 77816.1 102569.0 104221.0 95701.0 86673.0 81735.0 82657.8 65361.8 True False 80190.52569153192 92406.02054020464 79671.53094320254 96822.39146318467 83799.64320670848 90682.27108801804 78462.70598182065 79589.5428553909 83866.51395180583 77211.37693627593 1.0385843236251924 1.1967928070557419 1.0318625843048626 1.253991254981686 1.0853276619567342 1.1744677363137805 1.0162065371088702 1.0308007189287365 1.0861937356851246 1.0 16.23652582082833 -7.26970922982008 24.944169673478722 1.0358669703913812 1.1323206099943204 0.32788480798291186 0.0678637307729276 718.7470899073935 2167931.2729156967 0.026101430513948237 0.01791365113617119 5.373914719456816e-08 7.26970922982008 0.09645363960293918 RNS(ph)LPQIPMLNLEAR ddPTM_PC-9_Lapatinib_30min_R1 3 RNSLPQIPMLNLEAR 15 1 H0YB74;Q14289-2;Q14289 H0YB74 PTK2B Protein-tyrosine kinase 2-beta 1 RNS(1)LPQIPMLNLEAR;RNS(1)LPQIPMLNLEAR;RNS(1)LPQIPMLNLEAR 110.44 0.0002411 25907200.0 49285.0 38947.0 40735.0 38499.0 37319.0 38819.0 33023.8 42701.0 44388.0 29780.7 True False 48582.18686223794 38856.820614396536 37385.92554164724 41330.34488889913 35123.969791976946 37158.80186150877 34733.61077730559 44685.04434766455 39388.556013638066 34928.25431471158 1.3909136833607916 1.112475311943382 1.07036341423741 1.1832926007839741 1.0056033569700313 1.0638608367512286 0.9944273327933253 1.279338038054867 1.1276989585204615 1.0 15.09210691937803 -4.761964846056763 5.345482079086081 1.0960970959298224 1.4064363640556712 0.5277250268657984 0.0846419846834708 0.12907190554810274 11.040126378368058 0.021298377843472254 0.14909799936917764 1.729956384773399e-05 4.761964846056763 0.3103392681258488 RNS(ph)LQHHQDDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RNSLQHHQDDTK 12 1 Q6ZU80;H0YJH2 Q6ZU80 CEP128 Centrosomal protein of 128 kDa 1 RNS(0.966)LQHHQDDT(0.034)K;RNS(1)LQHHQDDTK 56.956 0.027292 8288900.0 14414.4 18715.4 14763.4 20168.9 26445.0 19424.4 11672.0 16982.800000000003 19837.4 14014.7 True False 16854.47322262279 20573.341226230354 15115.415446506287 19038.901921456043 21263.292087020898 18405.75026929811 10566.343662037882 16537.019494763994 20127.484446326318 16555.454169695837 1.0180616641417362 1.242692650733141 0.9130172625632048 1.150007829824812 1.2843677901596073 1.1117635360912765 0.638239431774647 0.9988864893259415 1.2157615393704484 1.0 14.015018968622043 -7.041778081164249 24.99939120150092 0.9505394093176174 1.126314797955283 0.17816504637983355 0.16399949290624483 824.9884913330159 493658.6666695072 0.06374997896342123 0.049385802779798885 9.082845332098753e-08 7.041778081164249 0.17577538863766562 RNS(ph)LQHHQDDTK ddPTM_PC-9_Lapatinib_30min_R1 1 RNSLQHHQDDTK 12 1 Q6ZU80;H0YJH2 Q6ZU80 CEP128 Centrosomal protein of 128 kDa 1 RNS(1)LQHHQDDTK 71.531 0.0099683 2986200.0 7874.5 6084.0 5054.9 5375.1 7659.3 5331.8 5118.6 6679.1 7851.4 6881.3 True False 7762.208185993554 6069.912871799849 4639.305634478279 5770.40278480796 7208.795032763177 5103.771343032855 5383.616062497847 6989.435369253324 6967.092653092676 8070.723536244107 0.9617735201974064 0.7520902982912261 0.5748314402846321 0.7149796122855854 0.8932030691411779 0.632380891268642 0.6670549472201639 0.8660233915664537 0.8632550256249975 1.0 12.978482300836756 -8.325861991982938 1.5707625982660445 0.9874300640689768 0.739203982950474 0.32871368370732545 0.11253641403176634 0.4329391858414715 2.1241819159117123 0.10920933814498773 0.03271278229251247 4.7221307502950515e-09 8.325861991982938 -0.24822608111850286 RNS(ph)LTASLDK ddPTM_PC-9_AZD4547_30min_R2 1 RNSLTASLDK 10 1 A0A0U1RRJ3;A0A0U1RQP0;A0A0U1RR07;Q9HCH5-11;Q9HCH5-7;Q9HCH5-8 A0A0U1RRJ3 SYTL2 Synaptotagmin-like protein 2 1 RNS(0.995)LT(0.005)ASLDK 77.89399999999999 0.0096914 2120000.0 14905.0 15434.0 15292.0 15094.0 20607.0 18146.0 16699.0 18402.0 15517.0 16993.0 True False 19644.479956740557 20422.73867168005 15089.218088384703 11614.311499975345 17746.073752712073 17011.327751426295 18185.1786497505 15558.393735892141 16337.196941416641 16398.080242266646 1.1979743766655195 1.2454347319901327 0.9201819887118065 0.7082726348685034 1.0822043489561006 1.037397518496036 1.108982172369028 0.9487936091317457 0.9962871689886554 1.0 14.00123930493682 -5.257070765815482 24.923566356621965 0.9747145914961408 1.2217045801902289 0.46817748269138115 0.10506140135248035 323.3236527347381 1844590.0891469074 0.029145345261543523 0.07178414394409476 5.5325995130855245e-06 5.257070765815482 0.24698998869408806 RNS(ph)LTGEEGQLAR ddPTM_PC-9_AZD4547_30min_R2 4 RNSLTGEEGQLAR 13 1 Q9BX95 Q9BX95 SGPP1 Sphingosine-1-phosphate phosphatase 1 1 RNS(0.999)LT(0.001)GEEGQLAR;RNS(0.979)LT(0.021)GEEGQLAR;RNS(0.999)LT(0.001)GEEGQLAR;RNS(0.997)LT(0.003)GEEGQLAR 120.54 9.671799999999999e-05 164434000.0 41442.5 40651.5 72354.3 65513.0 63970.4 42696.0 39411.2 74894.1 36496.5 37982.4 True False 54620.352942450234 53791.302391590114 71394.8347065403 50409.99001576019 55089.21416948088 40026.212370489186 42918.72045038907 63320.93774020647 38425.63048091852 36652.64773694279 1.4902157501543198 1.467596632517574 1.9478765959540847 1.375343750813155 1.5030077653559413 1.092041498823184 1.1709582554149451 1.7275951847916375 1.0483725693352492 1.0 15.161629799981723 -6.354765275050024 2.0853161923927845 1.2574676178652118 1.6059198405052315 0.3305658201784797 0.2398317104949073 0.4232569165407379 3.6185899374562935 0.083259437707598 0.10084355085505405 4.4180916928038825e-07 6.354765275050024 0.34845222264001974 RNS(ph)LTGEEGQLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RNSLTGEEGQLAR 13 1 Q9BX95 Q9BX95 SGPP1 Sphingosine-1-phosphate phosphatase 1 1 RNS(1)LTGEEGQLAR;RNS(1)LTGEEGQLAR;RNS(0.998)LT(0.002)GEEGQLAR 109.1 0.00037774 127071000.0 67724.0 42398.2 84257.0 65378.0 93645.0 51194.6 42742.0 63410.0 61328.0 30381.8 True False 79188.33559002828 46607.21309605779 86266.0064264521 61715.0826183358 75295.9344862573 48509.86505305741 38693.16833471755 61745.554688448574 62224.80597882283 35889.77983780352 2.2064313558874886 1.2986207579620022 2.40363710271597 1.7195726164173875 2.097977051587995 1.3516345118941315 1.078111053051408 1.7204216623087383 1.7337750819323785 1.0 15.131285452664898 -6.769936092696069 24.944176049925872 1.4031473815912847 1.9222526251059762 0.3899702170447382 0.3541428246347013 210.40226328477436 617683.4655682087 0.1205944274778645 0.10804446908345872 1.6984935708083444e-07 6.769936092696069 0.5191052435146915 RNS(ph)LTGEEGQLAR ddPTM_PC-9_Lapatinib_30min_R1 2 RNSLTGEEGQLAR 13 1 Q9BX95 Q9BX95 SGPP1 Sphingosine-1-phosphate phosphatase 1 1 RNS(1)LTGEEGQLAR;RNS(0.999)LT(0.001)GEEGQLAR 128.85 4.5817e-05 118323000.0 74276.0 108405.0 52181.0 32027.8 18210.7 19101.9 38885.0 41159.0 62280.0 0.0 True False 73216.8106194498 108153.99488288337 47890.87960448494 34383.23125360877 17139.582429613736 18284.956265703775 40898.275034233775 43071.39739831679 55265.37056252543 0.0 0.0 RNS(ph)NSPPS(ph)PSSMNQR ddPTM_PC-9_Lapatinib_30min_R1 1 RNSNSPPSPSSMNQR 15 1 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 2 RNS(0.793)NS(0.329)PPS(0.742)PS(0.12)S(0.015)MNQR 114.28 0.00057016 0.0 2912.6 1131.6 2781.1 2239.2 3235.3 3267.6 2075.6 3092.7 3146.9 2982.5 True False 2871.0657898945756 1128.9798497252966 2552.4486933564526 2403.878237752225 3045.0060148445295 3127.8523651476335 2183.0644120112 3236.3981324564324 2792.462983673912 3498.0211510685576 0.820768561967539 0.3227481484439914 0.7296836077096742 0.6872108926550945 0.870493883067104 0.8941776593295192 0.6240855380032019 0.9252082799636 0.798297912755869 1.0 11.772323297320584 -4.394934245626824 0.15846441529496041 1.0411418142212994 0.10654511746979278 0.3190171871315237 0.1511784996205939 29.034220400214526 0.7020460153184495 0.5895981257553301 5.634796613047153 4.027780123300103e-05 4.394934245626824 -0.9345966967515066 RNS(ph)NSPPSPSS(ph)MNQR ddPTM_PC-9_AZD4547_30min_R2 1 RNSNSPPSPSSMNQR 15 1 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 2 RNS(0.855)NS(0.143)PPS(0.007)PS(0.025)S(0.969)MNQR 82.12100000000001 0.026317 1745500.0 4849.1 3093.6 4315.4 7462.5 6094.4 6228.6 4341.1 5936.9 4229.0 5930.7 True False 6391.012932454258 4093.5457013547593 4258.174976367728 5742.1359194756815 5248.297757001426 5839.1246573643675 4727.449490174971 5019.488521389963 4452.536306325386 5723.067998164585 1.116710990417008 0.7152711976631377 0.7440371104682566 1.0033317656399001 0.9170427048367379 1.020278748957203 0.8260341291927837 0.8770625341162707 0.7779981485024003 1.0 12.482573032913995 -4.7333041465652705 24.889773116024152 0.8759673883348618 1.116712392258 0.3233106303338388 0.10461362587198478 3980.089172827847 3520778.2771094902 0.02687778009725443 2.697528825640374 1.8479739863724536e-05 4.7333041465652705 0.24074500392313825 RNS(ph)NSPPSPSS(ph)MNQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RNSNSPPSPSSMNQR 15 1 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 2 RNS(0.934)NS(0.034)PPS(0.058)PS(0.014)S(0.959)MNQR 108.77 0.00085066 0.0 2487.7 2699.0 3146.0 3151.9 3478.7 3603.7 3423.5 2715.6 3755.6 3086.4 True False 2908.818475685338 2966.9388829304053 3221.0125712714416 2975.3092615976725 2797.073707056897 3414.7156280487184 3099.201296006398 2644.3183774160384 3810.5185451028424 3645.939888071044 0.7978240357726537 0.8137651672858826 0.8834519136780341 0.8160609754791701 0.7671749378558032 0.9365803422105625 0.8500417974927423 0.7252775576656769 1.045140255211084 1.0 11.83207506000054 -8.276644988972615 24.977242169610307 1.0225701790908193 0.8279201767342788 0.664395115335682 0.05645465248570321 546.1657967129506 897141.097797363 0.05340032274951978 0.014009530600149487 5.288774023048805e-09 8.276644988972615 -0.1946500023565405 RNS(ph)NSPPSPSSMNQR ddPTM_PC-9_AZD4547_30min_R2 1 RNSNSPPSPSSMNQR 15 1 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 RNS(0.827)NS(0.172)PPSPSSMNQR 73.984 0.0061384 1516700.0 3422.6 2949.7 4750.4 6499.1 5969.6 4653.4 2933.3 4955.9 3106.6 4178.6 True False 4510.915605497502 3903.132840472634 4687.406592143778 5000.832905094062 5140.824082796623 4362.4221623766725 3194.358017444945 4190.079530252573 3270.8085337504012 4032.308485866854 1.1186930814713594 0.9679648405257243 1.1624622988476767 1.2401910525005373 1.2749084304474942 1.0818671680668428 0.7921908823794346 1.0391267297476625 0.8111503733443282 1.0 11.977390298997404 -7.0601372368078925 6.832616826873614 0.9156554342590513 1.1509917724015493 0.5521923289551687 0.10323413773051326 0.2043082992642381 19.41561809075726 0.04102729694709603 0.031964089534287664 8.706884094405231e-08 7.0601372368078925 0.235336338142498 RNS(ph)NSPPSPSSMNQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RNSNSPPSPSSMNQR 15 1 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 RNS(0.915)NS(0.085)PPSPSSMNQR 68.625 0.010204000000000001 1884500.0 6016.1 4477.3 5414.0 5788.1 7975.3 6432.7 3874.1 6168.7 5692.7 4568.9 True False 7034.506906608743 4921.776754555133 5543.0902927093375 5463.811522273386 6412.597216170084 6095.357887878849 3507.117201944907 6006.778161277917 5775.944967969682 5397.205402607501 1.303360976999361 0.9119120706759319 1.0270297087510059 1.0123408532189095 1.1881328831902573 1.1293544405284366 0.6498024329869948 1.1129422938722915 1.0701732724826822 1.0 12.397996877973073 RNS(ph)NSPPSPSSMNQR ddPTM_PC-9_Lapatinib_30min_R1 1 RNSNSPPSPSSMNQR 15 1 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 RNS(0.614)NS(0.386)PPSPSSMNQR 65.905 0.012269 864390.0 7141.9 4801.2 5380.1 5115.7 5279.2 4138.2 3878.7 4662.6 5283.0 4716.4 True False 7040.05519633594 4790.08311638485 4937.768945786578 5491.925643474932 4968.68783530654 3961.2188326153587 4079.520107375141 4879.241417658152 4687.972907543703 5531.62345579203 1.2726924116580038 0.8659452608563348 0.8926437211875583 0.9928234789236186 0.8982331995327605 0.7161042077923185 0.7374905649269337 0.8820631875347944 0.84748590445632 1.0 12.433487238520245 -4.7613933303754745 8.789349317844298 0.8628482729844695 1.275975864367275 0.6573629679666166 0.08700438515993371 0.05462690759460263 52.50931584472272 0.023276612953244045 0.13388633424952548 1.7322344428036904e-05 4.7613933303754745 0.4131275913828054 RNS(ph)PAFLSTDLGDEDVGLGPPAPR ddPTM_PC-9_AZD4547_30min_R2 2 RNSPAFLSTDLGDEDVGLGPPAPR 24 1 Q9UPX8;Q9UPX8-3;H7C1X5;E7EUA2;A6NHU9;A0A0A0MSQ6;A0A590UJ45;Q9UPX8-4;A0A590UJF3 Q9UPX8 SHANK2 SH3 and multiple ankyrin repeat domains protein 2 1 RNS(1)PAFLSTDLGDEDVGLGPPAPR;RNS(1)PAFLSTDLGDEDVGLGPPAPR 152.38 2.9004e-07 4817900.0 26317.0 21410.9 26648.0 39937.0 34884.0 26758.0 25797.0 44047.0 27801.0 35019.0 True False 34685.2585723946 28331.554712030225 26294.630108506102 30730.141670499204 30040.958741670696 25084.818030015693 28092.88302458911 37240.54824936646 29270.504103133633 33792.995468954025 1.0264037884496007 0.8383854203767973 0.7781088874664353 0.909364240844861 0.8889699869687384 0.7423082115659553 0.8313226642011755 1.1020197449965552 0.8661707462431009 1.0 15.044436618676933 -7.732570975396742 24.99999566479158 0.9880715686621827 0.8539125141226487 0.3038660906640622 0.08999810448579074 237.3549802311557 205549.214286875 0.04170680443690204 0.02407425678353831 1.8510963505634598e-08 7.732570975396742 -0.13415905453953403 RNS(ph)PAFLSTDLGDEDVGLGPPAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RNSPAFLSTDLGDEDVGLGPPAPR 24 1 Q9UPX8;Q9UPX8-3;H7C1X5;E7EUA2;A6NHU9;A0A0A0MSQ6;A0A590UJ45;Q9UPX8-4;A0A590UJF3 Q9UPX8 SHANK2 SH3 and multiple ankyrin repeat domains protein 2 1 RNS(0.984)PAFLS(0.012)T(0.004)DLGDEDVGLGPPAPR 98.95700000000001 1.9503e-06 2893100.0 7636.8 9550.6 11363.0 9791.1 10643.0 10090.0 7465.3 7822.1 6923.6 4864.5 True False 8929.55940632463 10498.720450283483 11633.93701441747 9242.536410174494 8557.580551414763 9560.862637570159 6758.132739908447 7616.778163200021 7024.844551835671 5746.395342639185 1.5539410141286052 1.827009772958236 2.0245625858861067 1.6084059413026068 1.4892084587212662 1.6638017517915984 1.1760647043829382 1.3254880162320701 1.222478463970306 1.0 12.48844153601576 -7.230336169103227 0.6164132570487328 1.0608755385165494 1.8105667889170822 0.7364726194353974 0.1527097767231556 0.41627677370816535 0.3232005876886083 0.13987469036844688 0.1040232185576083 5.8838803259550405e-08 7.230336169103227 0.7496912504005329 RNS(ph)PAFLSTDLGDEDVGLGPPAPR ddPTM_PC-9_Lapatinib_30min_R1 2 RNSPAFLSTDLGDEDVGLGPPAPR 24 1 Q9UPX8;Q9UPX8-3;H7C1X5;E7EUA2;A6NHU9;A0A0A0MSQ6;A0A590UJ45;Q9UPX8-4;A0A590UJF3 Q9UPX8 SHANK2 SH3 and multiple ankyrin repeat domains protein 2 1 RNS(1)PAFLSTDLGDEDVGLGPPAPR;RNS(1)PAFLSTDLGDEDVGLGPPAPR 139.16 3.1157e-07 5335800.0 31181.0 33032.0 36961.0 27567.0 25603.0 22003.0 19026.8 16438.9 26331.0 24051.0 True False 30736.353222104917 32955.51643348002 33922.20925358594 29594.369140816187 24097.081877434724 21061.98298149816 20011.914605152593 17202.71130715492 23365.32550227772 28208.18330405693 1.089625407308112 1.1682963088495077 1.2025662513582438 1.0491412659162596 0.8542585538987567 0.7466621566681682 0.7094364918663323 0.6098482529600129 0.8283172741194323 1.0 14.783826134355444 -6.26847525554301 2.127822092301156 0.7508935122128791 1.1548892570112814 0.7385936344374999 0.09918177486480483 0.14596548724759226 1.2976062492358043 0.032663073712804476 0.04195174964089613 5.389205501531992e-07 6.26847525554301 0.4039957447984023 RNS(ph)PMAQTPPCHLPNIPGVTSPGTLIEDSK ddPTM_PC-9_AZD4547_30min_R2 1 RNSPMAQTPPCHLPNIPGVTSPGTLIEDSK 30 1 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 1 RNS(0.756)PMAQT(0.244)PPCHLPNIPGVTSPGTLIEDSK 70.67 2.2406999999999997e-05 6873900.0 26119.0 33158.0 33054.0 32508.0 28243.0 30969.0 33255.0 42674.0 33826.0 34634.0 True False 34424.29869105043 43875.67505996935 32615.68236290007 25013.78284359336 24321.94695966646 29032.503534328283 36214.63057652871 36079.713850965185 35613.97330285231 33421.47420176915 1.0300053936348563 1.312798914706366 0.9758899971316516 0.7484344554217559 0.7277341152826522 0.8686781247007788 1.0835737034786965 1.0795368759961916 1.0656015078164056 1.0 15.028487750790395 -5.424860166983018 7.128310872918725 0.9311831696798052 1.168749535095464 0.30916266028625383 0.13668514336347484 0.3226637734673081 20.350912449914656 0.04016744852635072 0.084103192172078 3.7595843492989195e-06 5.424860166983018 0.2375663654156588 RNS(ph)RDGDPLPSSLSCK ddPTM_PC-9_AZD4547_30min_R2 3 RNSRDGDPLPSSLSCK 16 2 H3BP35;P53602 H3BP35 MVD Diphosphomevalonate decarboxylase 1 RNS(1)RDGDPLPSSLSCK;RNS(1)RDGDPLPSSLSCK;RNS(1)RDGDPLPSSLSCK 83.964 0.0034952 29766100.0 117453.0 101693.0 164248.0 299967.0 232905.0 153444.0 121205.0 157053.0 130143.0 176927.0 True False 154800.61082583366 134563.2735349979 162069.96420226342 230814.24259395144 200570.16098293755 143849.1224231157 131992.01019480263 132784.0675689093 137022.09328779983 170732.83958238785 0.9066832790017176 0.7881510895275881 0.9492606378403018 1.3519030267318377 1.1747602949352434 0.8425392723214253 0.773090932697276 0.7777300951222906 0.8025526525708561 1.0 17.381381054454216 -6.883539762640218 8.081146471715629 0.8183237145100253 1.0330214613303477 0.2785976953438867 0.15548047070334176 0.34733039833212587 23.13344449563172 0.06183905287074886 0.05455545230630787 1.3075558177312768e-07 6.883539762640218 0.2146977468203224 RNS(ph)RDGDPLPSSLSCK ddPTM_PC-9_Lapatinib_30min_R1 2 RNSRDGDPLPSSLSCK 16 2 H3BP35;P53602 H3BP35 MVD Diphosphomevalonate decarboxylase 1 RNS(1)RDGDPLPSSLSCK;RNS(1)RDGDPLPSSLSCK 87.669 0.0023371999999999998 18252300.0 82607.0 72414.0 113812.0 85738.0 74104.0 88528.0 61942.0 68970.0 110134.0 68329.0 True False 81429.0090317316 72246.32983210307 104454.81668702478 92043.45853358376 69745.34841406945 84741.86380884734 65149.053675466326 72174.59798736371 97729.54915756553 80139.57660733048 1.0160898332507933 0.9015062580888978 1.3034111372815782 1.1485393663180947 0.8702984388825651 1.0574283942635139 0.8129448199443949 0.9006111716936847 1.2194917080286405 1.0 16.290227267305205 -6.248912436047503 24.40113188116905 0.9676653952557317 1.0938255115572584 0.13606200462942586 0.14155696805426957 1138.331320850595 2217344.171621609 0.043074647761330805 0.05519047401221509 5.637513098529058e-07 6.248912436047503 0.12616011630152668 RNS(ph)RTEEPTVASESVENGHR ddPTM_PC-9_AZD4547_30min_R2 1 RNSRTEEPTVASESVENGHR 20 2 Q14686;A0A0D9SFT8;F6M2K2 Q14686 NCOA6 Nuclear receptor coactivator 6 1 RNS(0.487)RT(0.487)EEPT(0.027)VASESVENGHR 73.735 0.00086694 4959800.0 7716.6 6380.3 16358.0 37618.0 20942.0 18655.0 13422.0 19094.0 11539.0 16227.0 True False 10170.318284749026 8442.607201433217 16141.082231872664 28945.75129230635 18034.564785232975 17488.49990096205 14616.531998140665 16143.4610364702 12148.927982664605 15658.897669114402 0.649491330721763 0.539157185890895 1.0307930080997543 1.8485178142136358 1.1517135603232365 1.1168410619003122 0.9334330108670613 1.0309449220242082 0.7758482263171782 1.0 13.93469503513642 -5.325608843641912 5.263497497464412 1.137832378152169 0.5944123364468271 0.37252381167021054 0.2683774849709257 0.2105331356018922 11.659671647672795 0.07611282051361624 0.1662208091616171 4.724884061883495e-06 5.325608843641912 -0.543420041705342 RNS(ph)SDSFCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RNSSDSFCR 9 1 Q96N46 Q96N46 TTC14 Tetratricopeptide repeat protein 14 1 RNS(0.615)S(0.384)DSFCR 78.28699999999999 0.010003 4919600.0 6138.2 4706.2 4990.9 5456.5 9212.9 6457.5 6958.2 9302.0 6369.9 4796.5 True False 7177.276025023811 5173.400433807731 5109.9019840936535 5150.789995211683 7407.698380356014 6118.857332220945 6299.068922994517 9057.832356283692 6463.047736833153 5666.067480926891 1.2667120624990698 0.9130495623679783 0.9018427686035506 0.9090590630186219 1.3073791311684513 1.0799125412498587 1.1117179497417626 1.5986100389333793 1.1406584476074555 1.0 12.468132068485202 -6.260513239260759 24.993557415714765 1.225253744690645 0.9847773323880894 0.23280694610300323 0.18311008789279423 113.92805544264698 3074559.3404486044 0.05574528978078423 0.06788743189760299 5.48891822645801e-07 6.260513239260759 -0.24047641230255568 RNS(ph)SDSFCR ddPTM_PC-9_Lapatinib_30min_R1 1 RNSSDSFCR 9 1 Q96N46 Q96N46 TTC14 Tetratricopeptide repeat protein 14 1 RNS(0.642)S(0.355)DS(0.003)FCR 77.279 0.010676999999999999 5988400.0 7449.4 7205.1 8211.1 2220.7 10463.0 8522.1 7844.6 7536.1 9612.3 7881.3 True False 7343.170189947349 7188.4170336300285 7536.015053762604 2384.0176860380357 9847.58691104946 8157.62964898539 8250.755004077415 7886.2547178856385 8529.661551993631 9243.57220382787 0.7944082685811072 0.7776665638694553 0.815270859315823 0.25791086318888556 1.065344294814018 0.8825191678177426 0.892593774586483 0.853160936485123 0.9227668009626624 1.0 13.174234777516368 RNS(ph)SEASSGDFLDLK ddPTM_PC-9_AZD4547_30min_R2 10 RNSSEASSGDFLDLK 15 1 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 RNS(0.578)S(0.422)EASSGDFLDLK;RNS(0.985)S(0.015)EASSGDFLDLK;RNS(0.967)S(0.033)EASSGDFLDLK;RNS(0.944)S(0.054)EASS(0.002)GDFLDLK;RNS(0.603)S(0.396)EAS(0.001)S(0.001)GDFLDLK;RNS(0.5)S(0.5)EASSGDFLDLK;RNS(0.987)S(0.013)EASSGDFLDLK;RNS(0.988)S(0.012)EASSGDFLDLK;RNS(0.5)S(0.5)EASSGDFLDLK;RNS(0.603)S(0.395)EAS(0.001)SGDFLDLK 253.52 3.7211e-50 7109646700.0 1371829.2999999998 1711419.2 1580187.0 1249869.0 1393058.0 1796044.0 1806105.0 2054838.0 1765720.0 1440607.0 True False 1808042.4815779543 2264601.987773467 1559232.6879041574 961731.0123335551 1199655.9426314135 1683737.0847560174 1966844.8461110021 1737310.0025797787 1859052.354411175 1390171.7874166446 1.300589249432143 1.6290087371013156 1.1216115173806531 0.6918073154978489 0.8629551782666611 1.2111719573052946 1.414821437116048 1.249708862102734 1.3372824648282144 1.0 20.406831741151017 -5.282962149437146 21.878051975940636 1.1106620207362627 1.4647988071724387 0.29577023853378304 0.21826581892634778 196.76301776982325 200011.50497785502 0.06451266102786053 0.13464942294282328 5.212401373623466e-06 5.282962149437146 0.35413678643617597 RNS(ph)SEASSGDFLDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 16 RNSSEASSGDFLDLK 15 1 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 RNS(0.995)S(0.005)EASSGDFLDLK;RNS(0.992)S(0.008)EASSGDFLDLK;RNS(0.968)S(0.032)EASSGDFLDLK;RNS(0.887)S(0.113)EASSGDFLDLK;RNS(0.877)S(0.123)EASSGDFLDLK;RNS(0.506)S(0.225)EAS(0.045)S(0.225)GDFLDLK;RNS(0.862)S(0.138)EASSGDFLDLK;RNS(0.999)S(0.001)EASSGDFLDLK;RNS(0.971)S(0.024)EAS(0.002)S(0.002)GDFLDLK;RNS(0.93)S(0.068)EAS(0.002)SGDFLDLK;RNS(0.986)S(0.014)EASSGDFLDLK;RNS(0.96)S(0.04)EASSGDFLDLK;RNS(0.488)S(0.488)EAS(0.008)S(0.017)GDFLDLK;RNS(0.597)S(0.397)EAS(0.003)S(0.003)GDFLDLK;RNS(0.778)S(0.222)EASSGDFLDLK;RNS(0.783)S(0.217)EASSGDFLDLK 222.93 1.6496000000000001e-24 3977035700.0 3804793.1999999997 6150434.699999999 4586411.2 4181992.0 4604072.0 2976419.7 4385713.300000001 3234812.6 3293845.0 3105529.8 True False 4448869.540668872 6761009.210209112 4695768.637069326 3947688.546440995 3701937.1422073855 2820331.0112445788 3970266.786409375 3149902.196817257 3342011.251782472 3668537.769379622 1.2127092101388424 1.8429711332513965 1.2800109831943796 1.0760931996915435 1.0091042739443874 0.7687888713550082 1.082247760824002 0.8586260779727313 0.9109927338563647 1.0 21.806773707807174 -5.705859592594345 2.3310153251795946 0.9372367997690515 1.5345400621319205 0.6575979558530382 0.16753889012496032 0.15649645666656062 1.727423809184439 0.04642740490820993 0.09120720892578213 1.9685226101984098e-06 5.705859592594345 0.597303262362869 RNS(ph)SEASSGDFLDLK ddPTM_PC-9_Lapatinib_30min_R1 13 RNSSEASSGDFLDLK 15 1 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 RNS(0.499)S(0.499)EASS(0.002)GDFLDLK;RNS(0.646)S(0.235)EAS(0.01)S(0.108)GDFLDLK;RNS(0.95)S(0.05)EASSGDFLDLK;RNS(0.959)S(0.041)EASSGDFLDLK;RNS(0.621)S(0.372)EAS(0.003)S(0.003)GDFLDLK;RNS(0.5)S(0.5)EASSGDFLDLK;RNS(0.837)S(0.163)EASSGDFLDLK;RNS(0.785)S(0.214)EASSGDFLDLK;RNS(0.585)S(0.413)EAS(0.001)SGDFLDLK;RNS(0.877)S(0.121)EAS(0.001)SGDFLDLK;RNS(0.955)S(0.045)EASSGDFLDLK;RNS(0.803)S(0.197)EAS(0.001)SGDFLDLK;RNS(0.872)S(0.128)EASSGDFLDLK 217.65 1.1006e-17 4712387700.0 832498.7000000001 1501535.5 1373139.5 1253460.7000000002 1672932.3 1512880.5 1636776.3 1724345.6 1414251.9000000001 1347340.0999999999 True False 820627.1158764347 1498058.7868038183 1260245.2707817561 1345644.381300318 1574533.7112254484 1448178.127711697 1721520.5680060557 1804464.9916090993 1254963.9582892682 1580226.041067164 0.5193099560125246 0.9480028476129554 0.7975094942307638 0.8515518326679218 0.9963977749424561 0.9164373261015925 1.0894141238448851 1.1419030852007106 0.7941673695250342 1.0 20.59169951063901 -4.138178126236762 0.6003853633646334 0.9997818588680903 1.9781459972151072e-17 0.5284945513517358 0.11590970426451534 6.0901795673802654 0.9451510094005621 0.055048068624483575 4.999173288565957 7.274813662616119e-05 4.138178126236762 -0.9997818588680903 RNS(ph)SIVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RNSSIVGR 8 1 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GUE9;Q96N67-7;A0A0U1RQT6 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 RNS(0.921)S(0.079)IVGR 86.898 0.0055609 22007000.0 23529.0 22809.0 14769.0 17070.0 17236.0 15777.0 12297.0 15094.0 11831.0 10840.0 True False 27511.994981066964 25073.326780570438 15121.148971744411 16113.6232416867 13858.72952966128 14949.626346178835 11132.139137429733 14697.79849341497 12004.005992946986 12805.206190607218 2.14850074036663 1.9580572469783457 1.1808594681463207 1.2583649963798513 1.0822730476473572 1.167464711122307 0.8693447783445533 1.14779865897013 0.9374316831971107 1.0 13.644442863080032 -5.2119681563171625 1.8722447053613174 1.0612417042151214 2.219536595658314 0.9275903886449245 0.10956078997515158 0.09722226378141859 0.5850124616212812 0.030511112456802908 0.14390903846054662 6.13807009556949e-06 5.2119681563171625 1.1582948914431925 up RNS(ph)SIVGR ddPTM_PC-9_Lapatinib_30min_R1 1 RNSSIVGR 8 1 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GUE9;Q96N67-7;A0A0U1RQT6 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 RNS(0.5)S(0.5)IVGR 80.102 0.029048 8327500.0 26767.0 26989.0 24626.0 24465.0 18852.0 17999.0 15111.0 13128.0 24215.0 28337.0 True False 26385.297671533383 26926.508628699215 22601.345339108982 26264.237712847542 17743.16242445803 17229.22472771829 15893.373641309143 13737.974806120239 21487.651704745553 33235.01269332092 0.7939006347013043 0.8101849960812715 0.6800462376128734 0.7902580918263269 0.5338695847113003 0.5184058416556816 0.4782117518042398 0.41335849433513516 0.6465365878757081 1.0 15.020416284448142 -6.261410490023536 24.999964809973278 0.559056139045388 0.7652429431261056 0.19862041733636104 0.15583967370083215 3.3065887732649513 2861071.51368956 0.04463146840140644 0.05398636400757149 5.477589848312342e-07 6.261410490023536 0.20618680408071766 RNS(ph)SSPVSPASVPGQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RNSSSPVSPASVPGQR 16 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 RNS(0.333)S(0.333)S(0.333)PVSPASVPGQR 73.688 0.006461399999999999 3213400.0 8655.3 6824.3 14705.0 14522.0 13353.0 12931.0 12652.0 12633.0 11944.0 8301.7 True False 10120.471340032676 7501.771403772498 15055.622969023052 13708.379420959234 10736.57550531254 12252.8755962755 11453.510967452306 12301.39713576992 12118.658404171994 9806.732493778964 1.0319921896975102 0.7649613577745035 1.5352333693790257 1.3978539161392782 1.0948168018372515 1.2494350798340101 1.1679232583042312 1.254382858263288 1.2357488502780751 1.0 13.259556809458738 -5.245209006792354 24.999854643129613 1.248949807159332 0.8984767607042283 0.4477547014570298 0.1524092670390243 718.9975356892309 1107477.0730592266 0.038418110414481434 0.1010062397098093 5.685792328654246e-06 5.245209006792354 -0.3504730464551036 RNS(ph)SSSSSPSERPR ddPTM_PC-9_AZD4547_30min_R2 4 RNSSSSSSPSERPR 14 2 B7WPE2;Q32P44;G3V1D0;H0Y3M3;Q32P44-2 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 RNS(0.967)S(0.032)S(0.001)SSSPSERPR;RNS(0.833)S(0.156)S(0.01)S(0.001)SSPSERPR;RNS(0.994)S(0.005)SSSSPSERPR;RNS(0.979)S(0.02)S(0.001)SSSPSERPR 127.07 8.415799999999999e-05 336003150.0 5976.0 6181.07 8117.549999999999 12777.9 10007.099999999999 9838.199999999999 6617.219999999999 9079.38 8595.2 8191.51 True False 7876.243691478137 8178.980000088206 8009.905983087048 9832.152571587045 8617.786900119609 9223.015798748054 7206.139760746272 7676.3704443965025 9049.524724551418 7904.727728201597 0.9963965821843759 1.0346947145197882 1.0133057403748655 1.2438319078984845 1.0902066707970268 1.166772103464515 0.9116240316585502 0.9711113030509088 1.1448243425596487 1.0 12.948500055665951 -7.254224665215823 24.913227381757924 1.0044825273671831 1.0917119133041073 0.18051451981204725 0.08758570560010195 998.3528008983744 3447429.905902111 0.035416973955705984 0.026851804396489376 5.568975852807978e-08 7.254224665215823 0.0872293859369242 RNS(ph)SSSSSPSERPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RNSSSSSSPSERPR 14 2 B7WPE2;Q32P44;G3V1D0;H0Y3M3;Q32P44-2 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 RNS(0.998)S(0.002)SSSSPSERPR;RNS(0.964)S(0.015)S(0.021)S(0.001)SSPSERPR;RNS(0.997)S(0.002)S(0.001)SSSPSERPR;RNS(0.986)S(0.012)S(0.002)SSSPSERPR;RNS(0.863)S(0.112)S(0.016)S(0.003)S(0.003)S(0.002)PSERPR 158.65 0.00062749 200816800.0 14070.57 13606.769999999999 12309.79 13005.56 15956.0 15018.800000000001 12413.649999999998 13859.599999999999 13323.810000000001 10073.130000000001 True False 16452.439594574837 14957.560201589824 12603.302078738541 12276.900637794424 12829.536341104389 14231.187688913642 11237.73920495687 13495.800185460055 13518.645515077942 11899.308730146791 1.3826382664475902 1.2570108517056104 1.0591625416700206 1.0317322557310415 1.0781749286495 1.1959675987613512 0.9444026926107194 1.1341667395576154 1.1360866266818153 1.0 13.538590144632538 -5.057695709934164 2.794625645673966 1.075602638342137 1.3781899208758162 0.6873869829815707 0.06902790118477282 0.1613544010949807 2.312749952786411 0.018040603234921095 0.08267793747964806 8.755970507296435e-06 5.057695709934164 0.30258728253367906 RNS(ph)SSSSSPSERPR ddPTM_PC-9_Lapatinib_30min_R1 4 RNSSSSSSPSERPR 14 2 B7WPE2;Q32P44;G3V1D0;H0Y3M3;Q32P44-2 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 RNS(0.995)S(0.005)SSSSPSERPR;RNS(0.991)S(0.007)S(0.001)SSSPSERPR;RNS(0.927)S(0.035)S(0.035)S(0.002)SS(0.001)PSERPR;RNS(0.92)S(0.039)S(0.039)S(0.002)SSPSERPR 121.95 0.00018201 199758050.0 6457.91 3277.9100000000003 6361.860000000001 5086.6 5234.860000000001 5824.1900000000005 4469.29 6425.58 4059.7200000000003 5100.89 True False 6365.819019164344 3270.3202007891896 5838.812428289776 5460.685532400176 4926.955826930744 5575.102970550005 4700.68796779608 6724.135904533059 3602.4715828531757 5982.572039991312 1.0640605707062392 0.5466411735501541 0.975970266510699 0.9127655289225914 0.8235514414194833 0.9318906539332039 0.785730273931295 1.1239540217125115 0.6021610034567018 1.0 12.546550148947793 RNS(ph)TIPTK ddPTM_PC-9_AZD4547_30min_R2 2 RNSTIPTK 8 1 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 1 RNS(0.783)T(0.217)IPTK;RNS(0.765)T(0.233)IPT(0.002)K 79.23 0.00963 10745500.0 81723.0 63036.0 83485.0 123109.0 105626.0 84398.0 79086.0 96776.0 84881.0 95715.0 True False 107709.21405600217 83411.15426383469 82377.93435186998 94728.1220650897 90961.65313747598 79120.57971811287 86124.50079011732 81821.49289124533 89367.63637200395 92364.04698337878 1.166137881283881 0.9030695058093849 0.8918831194858121 1.0255951872933453 0.9848166695623984 0.856616641455207 0.9324461584670031 0.885858681635825 0.967558690754271 1.0 16.495043766552115 -6.605770892717145 24.99641780581971 0.9215090384690725 0.985340386037587 0.1378061529302781 0.07980848020009029 57.51215833069325 17337.04050060404 0.026023911665131464 0.026023915564195307 2.4787293392140213e-07 6.605770892717145 0.0638313475685145 RNS(ph)TIPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RNSTIPTK 8 1 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 1 RNS(0.789)T(0.211)IPTK;RNS(0.857)T(0.143)IPTK 54.471000000000004 0.042745 7962800.0 57760.0 64574.0 72754.0 82396.0 74923.0 66118.0 71105.0 79017.0 64863.0 51986.0 True False 67537.62718799901 70984.47996530113 74488.73128108139 77779.6192514364 60242.375989255685 62650.65568591314 64369.419644380025 76942.8874754319 65811.4986662598 61410.650279050424 1.0997705916010914 1.155898523183636 1.2129611222581762 1.2665493509351433 0.980976031283074 1.0201920253445962 1.048180068960106 1.252924160968869 1.0716626247599055 1.0 15.906201259449942 -6.258785203642071 24.988719646291933 1.0721550508286355 1.1838855966990998 0.3488792039024893 0.08062874093804906 322.6339644851543 3037555.769557216 0.026171840050366695 0.03222685274346914 5.510801860512954e-07 6.258785203642071 0.11173054587046427 RNS(ph)TIPTK ddPTM_PC-9_Lapatinib_30min_R1 4 RNSTIPTK 8 1 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 1 RNS(0.785)T(0.215)IPTK;RNS(0.786)T(0.214)IPTK;RNS(0.83)T(0.17)IPTK;RNS(0.517)T(0.168)IPT(0.314)K 94.465 0.0030829 19575900.0 208014.0 176988.0 203061.0 177794.0 188940.0 166398.0 155671.0 142845.0 191714.0 170932.0 True False 205047.6822149039 176578.19516011016 186366.10841812717 190869.563863397 177826.9206703323 159281.5454326832 163730.88267594716 149482.10018131032 170121.15048208108 200477.36844742697 1.022797155623456 0.8807886721957641 0.9296117056075568 0.9520753656213843 0.88701743267827 0.7945113539060299 0.8167050672299891 0.7456307978249943 0.8485803250489768 1.0 17.613079856894956 -6.531422466108161 3.899555563768024 0.8240021256746349 0.9394283078110542 0.3158836265272472 0.07030458108745463 0.23132723181587722 7.932547684388802 0.022350088035159303 0.02352131357114778 2.941558798610286e-07 6.531422466108161 0.11542618213641931 RNS(ph)TIVLR ddPTM_PC-9_AZD4547_30min_R2 4 RNSTIVLR 8 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 RNS(0.785)T(0.215)IVLR;RNS(0.829)T(0.171)IVLR;RNS(0.856)T(0.144)IVLR;RNS(0.857)T(0.143)IVLR 105.46 0.0017611 50460100.0 43168.9 39743.7 45279.9 71342.0 66436.0 48271.6 41298.6 67682.0 52046.6 49230.2 True False 56895.712231099475 52590.07379458662 44679.45894063891 54895.20412291246 57212.50816883476 45253.16922108174 44974.09539401073 57223.30207763564 54797.67702076016 47506.66568250669 1.197636403517372 1.1070041022464725 0.9404882093649264 1.1555263526551063 1.2043048558952443 0.9525646258467104 0.9466902117395175 1.204532064196349 1.1534734385902867 1.0 15.535842332412274 -6.753027948119443 24.99959746434366 1.057687700492043 1.1121054360898925 0.09903918421410951 0.10228270907820966 649.6489006585138 1930816.8469823324 0.03685339214975884 0.036278056841961566 1.765924174646677e-07 6.753027948119443 0.05441773559784946 RNS(ph)TIVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RNSTIVLR 8 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 RNS(0.905)T(0.095)IVLR;RNS(0.822)T(0.178)IVLR;RNS(0.833)T(0.167)IVLR;RNS(0.774)T(0.226)IVLR 121.29 0.0015489 42219000.0 106103.0 119572.1 95989.3 99406.2 110479.4 75940.5 59634.2 93894.0 58385.2 59342.4 True False 124064.14227022625 131442.42786352054 98278.04895344758 93836.7928932489 88831.75465300884 71958.04649439019 53985.216861780245 91429.38198891621 59238.973096053436 70100.70736582013 1.769798721470787 1.8750513768368842 1.4019551677358142 1.3385998004779347 1.2672019725769792 1.0264952979558044 0.7701094452593568 1.304257623418727 0.8450552829219712 1.0 16.09714138167425 -5.654043763546771 0.77851988443738 0.9860320842427275 1.9603538315853954 0.805426500411958 0.1528553315097633 0.4254341549055893 0.4232943028086234 0.07016980564285179 0.2950516131996877 2.217972904982905e-06 5.654043763546771 0.974321747342668 RNS(ph)TIVLR ddPTM_PC-9_Lapatinib_30min_R1 3 RNSTIVLR 8 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 RNS(0.917)T(0.083)IVLR;RNS(0.889)T(0.111)IVLR;RNS(0.921)T(0.079)IVLR 131.09 0.0016134 30914900.0 108623.0 87281.0 98808.0 89569.0 63529.0 57267.0 65584.0 59698.0 73326.0 77691.0 True False 107074.0161009812 87078.90620702867 90684.38764990997 96156.20305342504 59792.349122819585 54817.82390589718 68979.61861502337 62471.78701826372 65067.25372298879 91119.7858332496 1.1750907349247732 0.9556531044353442 0.9952216943953709 1.055272487463833 0.6561950138056774 0.6016017641460936 0.7570212987688204 0.6856006787876775 0.714084796490443 1.0 16.475476735707943 -6.257273583919342 24.96609449558158 0.7143867161016507 1.0353277915717511 0.6388920857031624 0.1132325668161736 210.45003142927575 1261250.3531629995 0.03230468633041219 0.04021112805463531 5.53001635945623e-07 6.257273583919342 0.3209410754701004 RNS(ph)TTFPSR ddPTM_PC-9_AZD4547_30min_R2 1 RNSTTFPSR 9 1 Q96E09 Q96E09 FAM122A Protein FAM122A 1 RNS(0.994)T(0.005)T(0.001)FPSR 97.779 0.0021427 8229800.0 10273.0 9485.0 15478.0 18083.0 14299.0 14882.0 8431.2 11960.0 12700.0 10398.0 True False 13539.600308325775 12550.840760715642 15272.751606854456 13914.243729565002 12313.830668706252 13951.426187409133 9181.56046660137 10111.856813458859 13371.296072436135 10033.969184904883 1.3493763094962228 1.2508350912216417 1.522104695102194 1.3867138191432369 1.2272143198557153 1.3904194771095848 0.9150477041940812 1.0077623946335363 1.3326028639346361 1.0 13.292604792143091 -7.2470844924008775 24.803986595722506 1.0645001047864555 1.353039062216506 0.5603479099660995 0.12609519237038866 551.4322382793077 952827.7125315099 0.048843959040180025 0.037651290144712905 5.661291373661624e-08 7.2470844924008775 0.28853895743005054 RNS(ph)TTFPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RNSTTFPSR 9 1 Q96E09 Q96E09 FAM122A Protein FAM122A 1 RNS(0.718)T(0.236)T(0.046)FPSR 56.551 0.039548 1210400.0 2353.2 2982.4 4109.3 3960.3 5293.3 4286.0 3895.8 5376.7 4321.2 3892.7 True False 2751.5502821814257 3278.472962005055 4207.281296607035 3738.417230465834 4256.115863271992 4061.234614928218 3526.761620850512 5235.567322084553 4384.389375092766 4598.415695403756 0.5983691915743233 0.7129570659046722 0.9149414875241334 0.8129793994489202 0.9255613553002825 0.8831812702334707 0.7669514577326291 1.1385589448378162 0.9534565088308752 1.0 12.166921175813737 -3.8327569584479337 0.37941145278217997 0.9854302780225582 7.133646686336039e-22 0.6076706227405917 0.09153906062801981 8.961826919313944 0.5853975822803722 0.07767879847955636 4.640794116027653 0.00014697485538909703 3.8327569584479337 -0.9854302780225582 RNS(ph)TTFPSR ddPTM_PC-9_Lapatinib_30min_R1 2 RNSTTFPSR 9 1 Q96E09 Q96E09 FAM122A Protein FAM122A 1 RNS(0.788)T(0.211)T(0.001)FPSR;RNS(0.777)T(0.181)T(0.043)FPSR 95.618 0.0024609000000000002 17972900.0 15022.900000000001 14696.6 16996.1 15674.8 17180.3 15958.5 12334.8 16110.4 19758.4 13688.5 True False 14808.670691137553 14662.570925656413 15598.746264843277 16827.57708159993 16169.788531769396 15275.992156080467 12973.43558936008 16858.947997906726 17533.000926824057 16054.538986220263 0.9223977532987993 0.9132975377394152 0.9716097284532308 1.0481507501425718 1.0071786269071976 0.9515061235449969 0.8080852150594472 1.0501047717643524 1.0920899654529332 1.0 13.970693617528543 -5.340980544714878 4.547203725457264 0.9883686687639567 0.9177518663793871 0.14212017338385063 0.07254107380531327 0.470365402441704 17.637973927636928 0.020859209762143203 0.04649600991175693 4.560573456996067e-06 5.340980544714878 -0.07061680238456958 RNS(ph)TTIMSR ddPTM_PC-9_AZD4547_30min_R2 2 RNSTTIMSR 9 1 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 RNS(0.654)T(0.07)T(0.276)IMSR;RNS(0.401)T(0.299)T(0.299)IMSR 96.756 0.0073491 55526000.0 36517.0 42117.0 58328.0 77008.0 63269.0 54325.0 45179.0 65075.0 49640.0 52017.0 True False 48128.64639921469 55730.49660717561 57554.53260916181 59254.99536173985 54485.19145243556 50928.049162142255 49199.84347667989 55019.15402473545 52263.86905793145 50195.90066274257 0.9588162731172531 1.1102599190642881 1.146598264983043 1.1804747913552491 1.0854510175743628 1.0145858225419415 0.980156602971326 1.0960885908672 1.041197953774815 1.0 15.615281928286889 -6.640278807388143 5.2227768701934165 1.0298843849969839 1.1065131408830198 0.2446049127552482 0.060901562680721215 0.31332719737674236 13.078484807414746 0.021400252163626017 0.02131848598721221 2.289397438711973e-07 6.640278807388143 0.0766287558860359 RNS(ph)TTIMSR ddPTM_PC-9_Lapatinib_30min_R1 2 RNSTTIMSR 9 1 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 RNS(0.437)T(0.281)T(0.281)IMSR;RNS(0.745)T(0.2)T(0.055)IMSR 103.21 0.004301300000000001 9248400.0 33142.8 28620.9 38005.1 25725.8 33072.7 34220.7 31370.6 29388.2 36505.5 27974.2 True False 32670.177594354867 28554.630064512854 34880.467381928516 27617.761150753035 31127.428809429966 32757.160433347934 32994.81617047533 30753.683058898747 32393.86617004291 32809.50319672154 0.9957534985662143 0.8703158317668812 1.0631208638786678 0.8417610283569522 0.9487320982214795 0.9984046462678887 1.0056481493377902 0.93734071115017 0.9873318098056371 1.0 15.001826128204547 -6.653083312966035 6.548172778550383 0.9828826357343201 0.94012919885893 0.10712916952549967 0.059946638659038175 0.5106543594547502 27.77101775319244 0.019011357112152433 0.018960150633745867 2.222883422475107e-07 6.653083312966035 -0.04275343687539013 RNS(ph)VASPTSPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RNSVASPTSPTR 12 1 Q96HB5-2;Q96HB5;Q96HB5-5;Q96HB5-3;Q96HB5-4 Q96HB5-2 CCDC120 Coiled-coil domain-containing protein 120 1 RNS(0.999)VAS(0.001)PTSPTR;RNS(0.992)VAS(0.008)PTSPTR 75.316 0.0091124 6624100.0 13145.6 12044.3 16192.4 12110.2 24694.0 14443.6 10938.6 14100.2 13797.8 9519.2 True False 15370.89044256509 13239.978505994324 16578.488226018955 11431.704755798131 19855.38796736224 13686.152189495377 9902.416619394067 13730.084690396818 13999.566722126956 11244.955606054265 1.3669142841515025 1.1774149200612176 1.4743044620908174 1.0166073710102794 1.7657151048841964 1.2170925941341 0.8806096676862488 1.2209994571258747 1.2449641610492097 1.0 13.45699034506253 -6.997885116952502 24.999991534233878 1.0970300811202691 1.3527001271279824 0.2819366529072135 0.20561123585770627 94.09283406031209 1112250.6820013875 0.07064766562268096 0.06189636737074041 1.0048815744288623e-07 6.997885116952502 0.25567004600771326 RNS(ph)VDTATSSSLSTPSEPLSPTSSLGEERN ddPTM_PC-9_AZD4547_30min_R2 2 RNSVDTATSSSLSTPSEPLSPTSSLGEERN 30 2 P13807-2;P13807 P13807-2 GYS1 Glycogen [starch] synthase, muscle 1 RNS(0.451)VDT(0.09)AT(0.09)S(0.09)S(0.09)S(0.09)LS(0.09)T(0.007)PSEPLSPTSSLGEERN;RNS(0.823)VDT(0.047)AT(0.031)S(0.031)S(0.031)S(0.031)LS(0.005)TPSEPLSPTSSLGEERN 122.51 5.4588000000000006e-17 15184000.0 23250.0 23181.0 30591.0 37928.0 24826.0 24578.0 21256.0 27437.0 21217.3 22672.0 True False 30643.016369957593 30673.80492083809 30185.343352195694 29184.285581758624 21379.3384279531 23041.133774636593 23147.74282167174 23197.24208953771 22338.80316202356 21878.26018081971 1.4006148622741854 1.4020221291512605 1.3796957848896347 1.3339399632583206 0.9771955471439174 1.0531520141092552 1.0580248443139444 1.0602873307939873 1.0210502561628552 1.0 14.417210395179783 -6.182748572296526 4.644622177744066 1.0340909618535514 1.3882466513442022 0.9742927503887217 0.027970718256569285 0.03377241876176769 1.3360303246429137 0.008855417020936824 0.011509586097847246 6.565252408772703e-07 6.182748572296526 0.3541556894906508 RNS(ph)VDTATSSSLSTPSEPLSPTSSLGEERN ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RNSVDTATSSSLSTPSEPLSPTSSLGEERN 30 2 P13807-2;P13807 P13807-2 GYS1 Glycogen [starch] synthase, muscle 1 RNS(0.985)VDT(0.008)AT(0.001)S(0.001)S(0.001)S(0.001)LSTPSEPLSPTSSLGEERN;RNS(0.971)VDT(0.015)AT(0.004)S(0.004)S(0.002)S(0.002)LS(0.001)TPSEPLSPTSSLGEERN 124.31 7.4467e-16 21301000.0 24148.7 25812.0 23469.0 24813.0 21442.6 23939.0 20149.4 22972.0 19248.4 17442.3 True False 28236.597951434072 28374.444774434854 24028.58996667815 23422.808054831396 17241.076456992043 22683.59669779901 18240.702962976877 22369.00934084594 19529.871435604833 20604.450916829177 1.370412541708217 1.3771026895581746 1.1661844357644215 1.1367838992351045 0.8367646644206366 1.100907604350264 0.8852797406058682 1.0856396722795227 0.9478472158485595 1.0 14.330668397638984 -5.579612371057851 1.535239886386226 0.9835045440914194 1.3912140604806944 0.7703726026239472 0.08348595793343869 0.1841430551171783 0.8378841994899655 0.02446916484058058 0.07087152123084939 2.632616681975914e-06 5.579612371057851 0.407709516389275 RNS(ph)VDTATSSSLSTPSEPLSPTSSLGEERN ddPTM_PC-9_Lapatinib_30min_R1 3 RNSVDTATSSSLSTPSEPLSPTSSLGEERN 30 2 P13807-2;P13807 P13807-2 GYS1 Glycogen [starch] synthase, muscle 1 RNS(0.53)VDT(0.129)AT(0.091)S(0.091)S(0.091)S(0.046)LS(0.02)T(0.001)PSEPLSPTSSLGEERN;RNS(0.261)VDT(0.261)AT(0.078)S(0.078)S(0.078)S(0.078)LS(0.078)T(0.078)PS(0.01)EPLSPTSSLGEERN;RNS(0.702)VDT(0.15)AT(0.047)S(0.016)S(0.016)S(0.016)LS(0.047)T(0.007)PSEPLSPTSSLGEERN 92.976 3.5431000000000003e-09 20320600.0 47715.9 42952.6 51972.9 47050.5 62119.9 53375.4 55481.2 38166.6 54457.4 40322.2 True False 47035.46251597563 42853.14589369988 47699.88878319572 50510.75072586689 58466.129614422425 51092.65856613449 58353.74506440346 39939.9595700235 48323.8341501553 47291.83854404576 0.9945788525893037 0.9061425229596043 1.0086283437420163 1.0680648560284491 1.2362837101367792 1.0803694704858808 1.2339073053811405 0.8445423311852212 1.0218218542116604 1.0 15.529303609457186 -5.585500464595916 3.4771894627155455 1.0768430536562659 0.950731599457488 0.16099614891398972 0.10824004832674236 0.4097459425278949 9.996991846477373 0.03166541985080054 0.06118358926642561 2.5971649630271266e-06 5.585500464595916 -0.1261114541987779 RNS(ph)VERPAEPVAGAATPSLVEQQK ddPTM_PC-9_AZD4547_30min_R2 2 RNSVERPAEPVAGAATPSLVEQQK 24 2 Q9BTC0 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 RNS(0.987)VERPAEPVAGAAT(0.013)PSLVEQQK;RNS(1)VERPAEPVAGAATPSLVEQQK 86.35700000000001 5.6155e-05 79429000.0 76932.0 92684.0 95125.0 130345.0 99583.0 97502.0 81422.0 86467.0 79279.0 72227.0 True False 101394.77571499285 122642.2904655949 93863.58034642915 100295.97406017529 85757.61937770281 91405.18452659372 88668.4002646854 73105.51196399212 83469.52608871368 69698.35471418795 1.4547656990008218 1.7596152874556958 1.3467115648760368 1.4390005972373234 1.2304109577531506 1.3114396301235367 1.2721735057920365 1.0488843282424083 1.197582445539743 1.0 16.088836980066425 -5.821967638469521 0.2940234152615716 0.9982967960496926 1.8502952561283526 0.7172681426423029 0.10969933310965403 2.1656929650105163 0.24949756580220211 0.13450041126219658 0.6387565873110748 1.5067193354627854e-06 5.821967638469521 0.85199846007866 RNS(ph)VERPAEPVAGAATPSLVEQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RNSVERPAEPVAGAATPSLVEQQK 24 2 Q9BTC0 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 RNS(1)VERPAEPVAGAATPSLVEQQK;RNS(1)VERPAEPVAGAATPSLVEQQK;RNS(0.996)VERPAEPVAGAAT(0.004)PS(0.001)LVEQQK 88.555 4.5328000000000004e-05 67886000.0 40726.1 36978.5 36453.6 36813.7 42589.7 42830.9 44144.0 38073.9 46691.0 25118.399999999998 True False 47620.2243528595 40649.48109760726 37322.79207504785 34751.14774062574 34244.554017719594 40584.772204509776 39962.360745116544 37074.500467631646 47373.767544306305 29672.167082854998 1.6048785456042793 1.3699532286974454 1.2578384305679342 1.1711698590665274 1.154096831623282 1.3677724343888666 1.346796161990048 1.249470601999064 1.5965725527233077 1.0 14.856822676287306 -4.799144228287596 2.618860915949644 1.2764222117746225 1.6647483135166625 0.3209327400539854 0.14819096284376357 0.5632534747245502 5.234518079496345 0.03752382400800068 0.4813518440202257 1.588019283140499e-05 4.799144228287596 0.3883261017420401 RNS(ph)VERPAEPVAGAATPSLVEQQK ddPTM_PC-9_Lapatinib_30min_R1 3 RNSVERPAEPVAGAATPSLVEQQK 24 2 Q9BTC0 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 RNS(0.99)VERPAEPVAGAAT(0.009)PS(0.001)LVEQQK;RNS(0.993)VERPAEPVAGAAT(0.007)PSLVEQQK;RNS(0.993)VERPAEPVAGAAT(0.006)PS(0.001)LVEQQK 64.589 0.00088542 94888000.0 76310.1 95308.8 57910.3 70190.2 86743.7 81487.9 98671.8 91944.9 87173.8 88949.8 True False 75221.90398044161 95088.11832935538 53149.138674222515 75352.22145564317 81641.60611067587 78002.85247457276 103780.54299917472 96216.99571535978 77355.36866319012 104324.65441184145 0.7210366945812139 0.9114635353017986 0.5094590437309877 0.7222858477745435 0.7825725047540544 0.7476933704150281 0.9947844407850254 0.9222843464740833 0.7414869390107449 1.0 16.67072061594252 -7.162177254849575 6.611574057208946 0.9076676997497102 0.7308813064601123 0.3824856245900561 0.11338421678405938 0.28362126342578925 16.093729847632954 0.043928036629457635 0.033938674077667236 6.88371284134357e-08 7.162177254849575 -0.1767863932895979 RNS(ph)VTPLASPEPTK ddPTM_PC-9_AZD4547_30min_R2 1 RNSVTPLASPEPTK 14 1 Q5W015;Q5VX20;A0A1W2PR17;Q16875-3;Q16875-2;Q16875;Q16875-4;Q9H178 Q5W015 PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3;6-phosphofructo-2-kinase;Fructose-2,6-bisphosphatase 1 RNS(0.995)VT(0.005)PLASPEPTK 166.62 0.00063115 11025000.0 22828.0 24673.0 26090.0 28566.0 27903.0 29998.0 21378.0 33823.0 23781.0 20716.0 True False 30086.829148102897 32648.064743187882 25744.029553096847 21980.550040300488 24029.15009083928 28122.220317826832 23280.60058532642 28596.43252521899 25038.015110126264 19990.73914545966 1.5050383544690633 1.633159459769299 1.2877977830521532 1.0995366344566981 1.2020140884233803 1.4067624069925402 1.1645692745990315 1.430484001473946 1.252480707588691 1.0 14.287044195392614 -5.32886224465753 5.53930600136988 1.2419196388172251 1.5683735554213574 0.536461251230026 0.12590189929334208 0.1508727682109134 8.902873480727362 0.032394658855133755 0.0700138769060971 4.689621102415384e-06 5.32886224465753 0.32645391660413225 RNS(ph)VTPLASPEPTKKPR ddPTM_PC-9_AZD4547_30min_R2 1 RNSVTPLASPEPTKKPR 17 3 Q5W015;Q5VX20;A0A1W2PR17;Q16875-3;Q16875-2;Q16875;Q16875-4;Q9H178 Q5W015 PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3;6-phosphofructo-2-kinase;Fructose-2,6-bisphosphatase 1 RNS(0.969)VT(0.031)PLASPEPTKKPR 72.77199999999999 0.009544799999999999 24283000.0 32333.0 23845.0 51343.0 98974.0 74355.0 49898.0 33592.0 45089.0 44568.0 52372.0 True False 42614.22143182103 31552.429935610402 50662.15827307975 76157.07343305684 64032.09171072478 46777.870171975555 36581.62292367318 38121.53109214437 46923.773492624714 50538.47222079616 0.843203594395274 0.6243249656966646 1.002447364291964 1.5069128544356518 1.2669969806561765 0.9255893206982789 0.7238371346852893 0.7543071528873339 0.9284762959913135 1.0 15.625094431786314 -6.99484395455786 24.360298438616066 0.8302567830999954 1.052896456314842 0.1372917868427488 0.23188638907411369 216.4042979265122 1022415.0693628329 0.09386753096423192 0.08248363827531298 1.011942988064671e-07 6.99484395455786 0.22263967321484657 RNS(ph)VTPLASPEPTKKPR ddPTM_PC-9_Lapatinib_30min_R1 1 RNSVTPLASPEPTKKPR 17 3 Q5W015;Q5VX20;A0A1W2PR17;Q16875-3;Q16875-2;Q16875;Q16875-4;Q9H178 Q5W015 PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3;6-phosphofructo-2-kinase;Fructose-2,6-bisphosphatase 1 RNS(0.956)VT(0.044)PLASPEPTKKPR 69.878 0.012776000000000001 9762400.0 99826.0 48945.0 60934.0 32665.0 52835.0 53986.0 37759.0 35885.0 65886.0 40037.0 True False 98402.46293415366 48831.67085967183 55924.24173204201 35067.293067245664 49727.34917760665 51677.14462751259 39713.97626379405 37552.3481046332 58465.22486966203 46957.34210405087 2.0955713957597437 1.0399155631821688 1.1909584151530928 0.7467904164920892 1.0589898607850894 1.1005125569714593 0.8457458298170596 0.799711960302661 1.2450709995491507 1.0 15.519063130377637 -4.7578461893444395 5.097156144362567 0.9903871718591698 2.166161832288224 0.8182335357467964 0.15453481959747825 0.06894662491954032 4.8544417263831585 0.03802726725726002 0.2909738327547782 1.7464405665027988e-05 4.7578461893444395 1.1757746604290542 up RNS(ph)YPR ddPTM_PC-9_AZD4547_30min_R2 2 RNSYPR 6 1 Q14134-2;Q14134 Q14134-2 TRIM29 Tripartite motif-containing protein 29 1 RNS(1)YPR;RNS(1)YPR 81.191 0.022446 13964100.0 8496.1 6198.9 5786.6 10098.0 8055.1 3829.8 2345.34 6888.0 8171.2 8596.3 True False 11197.683070141793 8202.573198903552 5709.865903102729 7770.062112544786 6936.788406146983 3590.3220005738135 2554.0707164743885 5823.617870493699 8603.112950164577 8295.346153510081 1.3498753232140435 0.9888162648200916 0.6883215959211858 0.9366772608105055 0.8362265151782436 0.43281159509595746 0.307891999828562 0.7020343410298197 1.0371011397184755 1.0 13.018086468800757 -3.45769594722847 0.7958727318997474 0.6904175288981068 6.054433285848538 0.4036032398268282 0.22455124351212258 17.575848383462535 1.639265975891584 0.08655271686666842 134.22368335962332 0.0003485812739494752 3.45769594722847 5.364015756950431 RNS(ph)YPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RNSYPR 6 1 Q14134-2;Q14134 Q14134-2 TRIM29 Tripartite motif-containing protein 29 1 RNS(1)YPR;RNS(0.993)Y(0.007)PR 74.255 0.029672000000000004 16525200.0 8530.9 10630.400000000001 10109.2 9382.5 12745.7 10716.5 4728.799999999999 6963.200000000001 5824.0 10368.7 True False 9975.012877044672 11685.715858133892 10350.24166735449 8856.828943475419 10248.271580773015 10154.50787467994 4280.8538304527665 6780.423378120251 5909.164982074489 12248.463231415966 0.8143889309688955 0.9540556751773815 0.8450236957732995 0.7230971572628494 0.8366985626806897 0.8290434222502902 0.3495013006589141 0.553573395291681 0.4824413373686038 1.0 13.5803131306145 -7.177486797898737 11.017109424420246 0.5592730933656147 0.8350911938372674 0.32330434358019955 0.16475203167374045 0.6668054725977808 85.29436165075927 0.059488874315197324 0.04607695908407894 6.645278735580248e-08 7.177486797898737 0.27581810047165267 RNS(ph)YPR ddPTM_PC-9_Lapatinib_30min_R1 1 RNSYPR 6 1 Q14134-2;Q14134 Q14134-2 TRIM29 Tripartite motif-containing protein 29 1 RNS(1)YPR 67.169 0.034931 6961700.0 3607.2 2347.7 3174.6 3028.6 1341.4 633.41 1243.0 2706.3 2971.8 3241.0 True False 3555.7606665205362 2342.264044892257 2913.5966423103787 3251.333347113431 1262.5014892938696 606.3205308508271 1307.356457954289 2832.0445778338794 2637.0845895586563 3801.202531638959 0.9354304688909602 0.6161902780492852 0.7664933973023866 0.8553433604369295 0.3321321289211913 0.15950755735959188 0.3439323338003245 0.7450391170324699 0.6937500876654494 1.0 11.892240180055834 -6.248863782948198 24.83224084118106 0.5035781304373437 0.7787897373654566 0.19194232906826814 0.23898852018522843 1127.5148436167644 2226431.790989971 0.07380843823036694 0.09461131361361566 5.638144692666826e-07 6.248863782948198 0.275211606928113 RNSAPES(ph)ILLVPPTWPK ddPTM_PC-9_Lapatinib_30min_R1 1 RNSAPESILLVPPTWPK 17 1 Q13469-3;Q13469-4;Q13469-2;Q13469;Q13469-5 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 RNS(0.154)APES(0.846)ILLVPPTWPK 92.932 0.00089957 6200900.0 23120.0 43225.0 50248.0 47159.0 64638.0 49149.0 44884.0 48385.0 43931.0 44284.0 True False 22790.304560311273 43124.9151682361 46116.80340288917 50627.23017781225 60836.119923197504 47047.01184191488 47207.87390090134 50633.1437381267 38983.02816606139 51938.43039527907 0.43879463408626207 0.8303084024687031 0.8879129202002405 0.9747547200119855 1.1713122529926738 0.9058227498186238 0.9089199180957975 0.9748685771360736 0.7505623075125647 1.0 15.664514795276142 -4.566081696255495 1.6136826055947477 0.95501747096877 1.573966375499996e-11 0.7015878048364463 0.09961110028937913 1.0476015581746505 1.7213557022800088 0.028489638083275978 1.8539680102526286 2.7159283204990694e-05 4.566081696255495 -0.9550174709530304 down RNSEGS(ph)ELSCTEGSLTSSLDSR ddPTM_PC-9_AZD4547_30min_R2 2 RNSEGSELSCTEGSLTSSLDSR 22 1 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 RNS(0.25)EGS(0.71)ELS(0.033)CT(0.005)EGSLTSSLDSR;RNS(0.396)EGS(0.6)ELS(0.004)CTEGSLTSSLDSR 86.13600000000001 0.00010302 28630800.0 6181.6 5364.2 7726.7 10852.1 10298.599999999999 8547.7 5452.5 8077.2 7426.4 7534.5 True False 8147.220214732473 7098.072747351699 7624.238909463903 8350.316008273643 8868.817156775878 8013.210967754129 5937.761937107881 6829.054335591131 7818.94434270391 7270.719448323312 1.1205521369155964 0.9762545230635428 1.0486223493635305 1.1484855202602124 1.2197991161412645 1.1021207770026173 0.816667728594201 0.9392542765717591 1.0754017395770956 1.0 12.82788241265475 -7.204680681130432 23.475688353095634 0.9527687947053408 1.1018486103073157 0.4142215069863058 0.08427330523595739 152.98701286515336 63275.9521841186 0.03462740353426037 0.026822246594791068 6.241936106907015e-08 7.204680681130432 0.14907981560197492 RNSNS(ph)PPSPSS(ph)MNQR ddPTM_PC-9_AZD4547_30min_R2 1 RNSNSPPSPSSMNQR 15 1 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 2 RNS(0.472)NS(0.522)PPS(0.256)PS(0.119)S(0.631)MNQR 136.39 0.00010195 2179600.0 5217.5 4562.0 4143.2 6975.9 5847.4 5120.0 2373.5 4915.3 4487.7 4172.3 True False 6876.556469258229 6036.577285227705 4088.2584608812094 5367.7140315806255 5035.589443471082 4799.845590615153 2584.7369019212388 4155.753327357387 4724.91066017887 4026.2290469492837 1.7079397096070996 1.4993129339727167 1.0154063301438168 1.3331864553626922 1.25069621840978 1.1921441961311283 0.6419746298039654 1.0321701221906998 1.1735325052505359 1.0 11.975213532305938 -1.5228787454016535 0.4185971758113036 0.9944267081349609 14.431441447697392 0.5952116892057161 0.17768195975807635 56.909325190243074 0.731112272962731 0.1285451402820164 639.662807830195 0.029999999991619793 1.5228787454016535 13.43701473956243 RNSNS(ph)PPSPSSMNQR ddPTM_PC-9_AZD4547_30min_R2 1 RNSNSPPSPSSMNQR 15 1 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 RNS(0.265)NS(0.73)PPS(0.005)PSSMNQR 56.347 0.024893000000000002 1256100.0 2889.9 5165.4 3481.8 8068.3 5765.6 4332.1 3479.2 4698.0 3648.3 5432.6 True False 3808.828086345825 6835.0145350975845 3435.6290570322944 6208.278088992383 4965.145961500303 4061.2131021687337 3788.8420598965145 3972.032049300147 3841.1416898479324 5242.406327554746 0.7265419443598155 1.3037933551949015 0.6553534469417597 1.1842420638707256 0.9471120037763713 0.774684915364627 0.722729567905083 0.7576734425225011 0.7327058319875759 1.0 12.356013462828573 -6.723815132872353 5.237665718979318 0.7771383841384086 0.9796772386525426 0.15097419037240334 0.1927445578779211 0.29823958368760245 19.709190711904913 0.060824959349134955 0.05914729849176928 1.8887951857750768e-07 6.723815132872353 0.202538854514134 RNSNSPPS(ph)PSSMNQR ddPTM_PC-9_AZD4547_30min_R2 1 RNSNSPPSPSSMNQR 15 1 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 RNS(0.01)NS(0.01)PPS(0.805)PS(0.087)S(0.087)MNQR 52.644 0.031555 1959500.0 4910.7 3377.4 6922.0 15700.0 11754.0 6817.7 6769.1 8960.6 5118.5 8170.9 True False 6472.200451094661 4469.0785013432815 6830.209757245546 12080.607562582005 10122.159988808546 6391.388141237686 7371.536786515727 7575.945164103636 5389.053460375143 7884.839278028396 0.8208411386557818 0.5667938614546846 0.8662459076722538 1.5321311109340408 1.2837496912606179 0.8105920635627532 0.93490006918175 0.9608242979935542 0.6834702991844211 1.0 12.944865632556175 -11.0753113879267 3.239594997770309 1.001725857416635 0.9509965388613956 0.003007369942430227 0.2667988443373174 427326183.19310164 370728038.5373663 6169964.559119519 0.07280611679034178 8.407920799087155e-12 11.0753113879267 -0.05072931855523943 RNSNSPPS(ph)PSSMNQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RNSNSPPSPSSMNQR 15 1 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 RNSNSPPS(0.566)PS(0.217)S(0.217)MNQR 80.733 0.0035528 1604500.0 2332.3 0.0 818.06 3677.0 3113.8 4466.7 2756.1 5741.2 4729.3 3232.1 True False 2727.1123249752427 0.0 837.5656529098264 3470.989610994841 2503.6732426003286 4232.458388824048 2495.0222555639643 5590.499583304224 4798.457065543419 3818.0541447104797 0.7142675880470096 0.0 0.21936976825490737 0.9090991063611654 0.6557458715112539 1.1085380742145008 0.6534800610464261 1.464227423555343 1.2567807798616963 1.0 11.898621846741658 -6.359411647704139 0.8004038931590858 1.178837986592747 0.26397489962276904 0.5541441923870425 0.2851479896961581 0.4815478709302008 0.6754555875826378 0.16326463117178866 0.24757870215586622 4.3710759461767266e-07 6.359411647704139 -0.9148630869699779 RNSNSPPS(ph)PSSMNQR ddPTM_PC-9_Lapatinib_30min_R1 1 RNSNSPPSPSSMNQR 15 1 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 RNS(0.036)NS(0.09)PPS(0.495)PS(0.27)S(0.109)MNQR 51.942 0.033168 1607500.0 6859.4 2685.6 3137.8 3779.6 3484.9 2290.5 2381.3 711.02 3203.2 2209.3 True False 6761.583698140098 2679.3816582027716 2879.8221962582716 4057.564392375986 3279.925033577012 2192.5406544162865 2504.592062209613 744.0565849061246 2842.4218848086293 2591.174561292796 2.6094666870944385 1.034041356467303 1.1113964451786924 1.5659170373884708 1.2658062805080113 0.8461570621943656 0.9665856170492869 0.28715031245710354 1.0969627161631597 1.0 11.339390494401773 -3.144023127928861 1.5115850161771225 0.9917330014790472 199.9970087587417 0.6894900286504178 0.3161598516007183 107.59198079157527 2.601404822711928 0.09685915306217537 72351.17941081563 0.0007177560668545952 3.144023127928861 199.00527575726267 RNSNSPPSPS(ph)SMNQR ddPTM_PC-9_AZD4547_30min_R2 1 RNSNSPPSPSSMNQR 15 1 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 RNSNSPPS(0.038)PS(0.707)S(0.255)MNQR 76.068 0.0053332 2497200.0 5316.4 2830.7 8609.6 20316.0 15835.0 10258.0 6035.2 8481.0 6786.7 11050.0 True False 7006.904612010436 3745.668417644465 8495.431078587295 15632.460079071088 13636.583581996187 9616.565638384813 6572.321108268409 7170.456323992025 7145.431106677344 10663.142863358242 0.6571143894253038 0.3512724593155087 0.7967098619470011 1.4660274441964865 1.2788521880219368 0.9018509609798269 0.6163587220474065 0.6724524294457186 0.6701055400121468 1.0 13.380345101427922 -12.036349119787033 2.137768984867561 3.0944135393910335 0.8328163716476027 0.02740422542084575 0.3110907816635694 17799317.817584414 992606.690225883 181798622.0847504 0.09131944189490321 9.197099399031363e-13 12.036349119787033 -2.261597167743431 RNSNSPPSPS(ph)SMNQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RNSNSPPSPSSMNQR 15 1 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 RNSNSPPS(0.243)PS(0.548)S(0.209)MNQR 60.09 0.019455 1434700.0 3928.7 2771.8 5285.9 5980.3 5725.6 6951.9 4999.1 7250.0 7411.1 4394.8 True False 4593.75131463801 3046.965985811968 5411.935902887384 5645.243179394198 4603.709781563503 6587.330125879481 4525.549057650237 7059.695182009971 7519.473317076276 5191.542450782342 0.8848528848966173 0.5869095773940564 1.0424524029600932 1.0873922794454827 0.8867710945654976 1.2688579913059943 0.8717156992462342 1.3598454118286383 1.4484083272675783 1.0 12.341947523724276 -5.76017522570085 0.5337994507105175 1.2304613964325823 0.6523992238308111 0.3761723857525102 0.19448825619453916 1.7455890929107025 0.7716119998854117 0.13731143274798133 0.56375295160559 1.7370998160517908e-06 5.76017522570085 -0.5780621726017713 RNSS(ph)DSFCR ddPTM_PC-9_AZD4547_30min_R2 2 RNSSDSFCR 9 1 Q96N46 Q96N46 TTC14 Tetratricopeptide repeat protein 14 1 RNS(0.448)S(0.552)DSFCR;RNS(0.48)S(0.519)DS(0.001)FCR 92.11200000000001 0.0033375999999999996 15644400.0 19099.2 21888.0 26155.0 37662.0 24084.0 24652.0 15272.5 22655.0 16087.7 19111.6 True False 25172.348311961054 28962.867956831193 25808.167610626602 28979.60777209959 20740.352320100803 23110.50654293845 16631.722913247162 19154.190310109578 16938.06297830951 18442.50870111831 1.3649091194645695 1.5704407912289586 1.3993848683428658 1.5713484668353355 1.1245949591902948 1.253110784301112 0.9018145623669221 1.0385891974093586 0.9184251043504958 1.0 14.1707472958638 -6.677283839053439 1.2464445869240919 0.9679903121347093 1.4832468165801789 0.8067098384980338 0.1061365191053534 0.17299040136995125 0.5662148809055847 0.04694116679708561 0.04578422864490156 2.1024039360237516e-07 6.677283839053439 0.5152565044454696 RNSS(ph)EASSGDFLDLK ddPTM_PC-9_AZD4547_30min_R2 3 RNSSEASSGDFLDLK 15 1 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 RNS(0.385)S(0.614)EAS(0.001)S(0.001)GDFLDLK;RNS(0.36)S(0.64)EASSGDFLDLK;RNS(0.043)S(0.955)EAS(0.001)S(0.001)GDFLDLK 128.82 7.7401e-06 62074000.0 81288.2 100517.4 126957.0 171855.1 133980.6 124178.9 108751.0 153126.0 115694.8 113537.9 True False 107136.15670040384 133007.683825109 125273.46722776991 132236.5618298271 115379.70636349832 116413.97375242978 118429.6283213977 129463.8951854268 121810.19093238453 109562.97267924718 0.9778500352856616 1.2139838904745472 1.1433923721156805 1.2069457280696312 1.053090323692476 1.0625302591345287 1.0809274833032163 1.181639125148976 1.111782456733735 1.0 16.74140078954516 -6.282953827707341 24.968189936782725 1.089750294283572 1.1417066113544596 0.10376355421372552 0.0744840826684767 1957.743687825877 2272018.1582121653 0.022947177821331814 0.026034855446973267 5.212501251962363e-07 6.282953827707341 0.05195631707088766 RNSS(ph)EASSGDFLDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 RNSSEASSGDFLDLK 15 1 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 RNS(0.191)S(0.809)EASSGDFLDLK;RNS(0.065)S(0.932)EAS(0.001)S(0.002)GDFLDLK;RNS(0.246)S(0.754)EASSGDFLDLK;RNS(0.237)S(0.762)EASSGDFLDLK;RNS(0.343)S(0.657)EASSGDFLDLK;RNS(0.373)S(0.627)EASSGDFLDLK;RNS(0.38)S(0.62)EASSGDFLDLK 141.0 9.3435e-07 1446600000.0 130908.40000000001 204907.0 149626.3 146367.5 150381.8 109362.2 146618.2 105287.2 112437.59999999999 102531.40000000001 True False 153068.6065612435 225248.81277681334 153193.95845290288 138167.00350483734 120915.56581478364 103627.05371084982 132729.46267215558 102523.5225610096 114081.78718895942 121119.53118188426 1.2637813659580763 1.8597232880513626 1.2648163096243552 1.140749160408762 0.9983159993676467 0.8555767405938344 1.0958551554566107 0.8464656489385747 0.9418942269322665 1.0 16.886072000635316 -5.7151813932529585 1.9834478824609907 0.955841236232574 1.5628322573415763 0.683063447883254 0.1587406005720225 0.1667314315673593 1.3333683739466728 0.045184379479723265 0.0939267688133477 1.9267200054123976e-06 5.7151813932529585 0.6069910211090023 RNSS(ph)EASSGDFLDLK ddPTM_PC-9_Lapatinib_30min_R1 11 RNSSEASSGDFLDLK 15 1 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 RNS(0.348)S(0.651)EASS(0.002)GDFLDLK;RNS(0.141)S(0.859)EASSGDFLDLK;RNS(0.356)S(0.64)EAS(0.003)S(0.001)GDFLDLK;RNS(0.306)S(0.694)EASSGDFLDLK;RNS(0.332)S(0.666)EAS(0.001)S(0.001)GDFLDLK;RNS(0.35)S(0.65)EASSGDFLDLK;RNS(0.199)S(0.8)EAS(0.001)S(0.001)GDFLDLK;RNS(0.429)S(0.571)EASSGDFLDLK;RNS(0.371)S(0.628)EAS(0.001)S(0.001)GDFLDLK;RNS(0.108)S(0.885)EAS(0.001)S(0.006)GDFLDLK;RNS(0.388)S(0.612)EASSGDFLDLK 161.49 1.8113999999999998e-10 2140437600.0 206365.4 379791.80000000005 338362.6 316415.1 398129.5 405736.6 417418.89999999997 382680.8 347444.50000000006 335214.5 True False 203422.5915532203 378912.415421438 310543.733145407 339685.3219838316 374712.3055627131 388384.1914362102 439030.8081956366 400461.54701294453 308311.6416572154 393155.879679756 0.5174095112577677 0.9637714581048108 0.7898743200746724 0.8639965457480155 0.9530883930005929 0.9878631136142931 1.1166838164883808 1.0185821138911602 0.7841969498417518 1.0 18.584741904613175 -4.2697131170114115 0.8807067026427068 0.9693851890516872 3.774747777527224e-55 0.5508545736296591 0.107819611686433 4.130104880101464 1.3356963739507053 0.038191048012463015 4.783812210918765 5.373866619971103e-05 4.2697131170114115 -0.9693851890516872 RNSS(ph)SPVSPASVPGQR ddPTM_PC-9_AZD4547_30min_R2 2 RNSSSPVSPASVPGQR 16 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 RNS(0.054)S(0.915)S(0.031)PVSPASVPGQR;RNS(0.073)S(0.462)S(0.462)PVS(0.002)PASVPGQR 115.74 7.8451e-05 54996000.0 30223.0 14405.9 40333.0 55588.0 52851.0 42881.0 32173.0 51201.0 30793.0 42901.0 True False 39833.285322547476 19062.32545227132 39798.15806688595 42773.045426038756 45513.55092466564 40199.64429124385 35036.334672640434 43289.06193193203 32420.65511484455 41399.04904804814 0.962178751408434 0.46045322031787256 0.9613302474821541 1.0331890806572863 1.099386386190711 0.9710282051306964 0.8463077166815335 1.0456535337729698 0.7831255997502944 1.0 15.337310008399125 -5.463360725489676 22.48432863872352 0.9728064245166183 0.7112080599889268 0.3401100010975894 0.14267547853538223 85.34064883367493 32238.406530416363 0.0351637254938921 0.07319850385784546 3.440640320702697e-06 5.463360725489676 -0.2615983645276915 RNSSEASSGDFLDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RNSSEASSGDFLDLK 15 1 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 0 ; 134.02 5.247000000000001e-06 7907800.0 64106.0 92462.0 118911.0 60153.0 77491.0 54093.0 62344.0 53997.0 50286.0 41304.0 False True 74957.87964878575 101641.0162999302 121746.28921247878 56782.822428657244 62307.19482379804 51256.267854715836 56438.324988527194 52579.63596455065 51021.337618234495 48792.08823771593 1.536271193878598 2.083145443677945 2.495205546836378 1.1637711046924313 1.276993813428035 1.0505036719271859 1.1567105862237061 1.077626268184746 1.0456887471111633 1.0 15.574359609600158 -5.805866898443822 11.904968204515066 1.1194052608536909 2.0424392343329902 0.7775561138396323 0.2274244129725408 0.34342290301745415 91.29484287137785 0.06486006734488717 0.09636855724595343 1.5636267858909124e-06 5.805866898443822 0.9230339734792994 RNSSEASSGDFLDLK ddPTM_PC-9_Lapatinib_30min_R1 2 RNSSEASSGDFLDLK 15 1 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 0 ; 128.85 1.0639000000000001e-05 8424700.0 57426.0 80799.0 82802.0 67776.0 88821.0 73612.0 75193.0 89235.0 82821.0 69891.0 False True 56607.09470936135 80611.91487977596 75994.33918496307 72760.47313410793 83596.72340880478 70463.78635795314 79086.12561782525 93381.18386838376 73492.82683620622 81971.56622609618 0.6905698806977304 0.9834131344694573 0.9270817026400768 0.8876306319854623 1.0198258647178469 0.8596125412999677 0.9647994940061017 1.139189943142202 0.896564872671779 1.0 16.32283594320237 -4.758901964061726 24.999509611206324 0.9635154727085182 0.6905695213760427 0.5369396583897021 0.0762398891980767 54.59627305117468 537791.1205049498 0.018951811680292144 0.1251883724831177 1.7422001064466064e-05 4.758901964061726 -0.27294595133247557 RNSSS(ph)PVSPASVPGQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RNSSSPVSPASVPGQR 16 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 RNS(0.076)S(0.228)S(0.696)PVSPASVPGQR;RNS(0.057)S(0.332)S(0.551)PVS(0.06)PASVPGQR 92.95200000000001 0.0070801 4790600.0 13694.5 8441.4 22903.8 24496.5 24356.0 18061.5 15509.5 18660.3 18978.3 11413.4 True False 16012.708371295912 9279.40640473091 23449.913455145204 23124.040523724558 19583.61664100894 17114.32314454642 14040.327880943834 18170.486897222163 19255.82173408384 13482.559071575306 1.18766090964547 0.6882526051225898 1.7392776349546013 1.715107673622285 1.4525148035357938 1.269367562470229 1.0413696544111162 1.3477031178398626 1.4282022894807893 1.0 13.718806734338553 -11.180788940897568 8.224810601989693 0.9995094188787794 1.319469464857897 0.09627429138146149 0.2930439292672742 0.002836439845636192 0.00011797466675863937 0.30522912868252045 0.07392179590270186 6.594943194448558e-12 11.180788940897568 0.31996004597911765 RNSSS(ph)PVSPASVPGQR ddPTM_PC-9_Lapatinib_30min_R1 2 RNSSSPVSPASVPGQR 16 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 RNS(0.104)S(0.104)S(0.792)PVSPASVPGQR;RNS(0.199)S(0.199)S(0.603)PVSPASVPGQR 81.788 0.0031719 55654000.0 57278.0 31480.0 46747.0 38794.0 39058.0 29081.0 18227.4 18349.6 42060.0 19463.2 True False 56461.20521650125 31407.109994125432 42903.64210863836 41647.04017299031 36760.68523098248 27837.273421122034 19171.12558464684 19202.189404508215 37322.75988856485 22827.38818691618 2.473397515045665 1.3758521008604405 1.8794809882467918 1.8244329939095205 1.6103763133117592 1.2194681753857997 0.839830007168101 0.8411908207490073 1.6349991327504072 1.0 14.478478181497623 -6.689497911229075 2.3341944725674755 1.0607274334360821 1.8481288565276797 0.5678717664847119 0.3241866985586226 0.22281831632604035 2.4849072070598246 0.11892774755267457 0.1149171833518058 2.0440997672253703e-07 6.689497911229075 0.7874014230915976 RNSSSPVS(ph)PASVPGQR ddPTM_PC-9_AZD4547_30min_R2 1 RNSSSPVSPASVPGQR 16 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 RNSS(0.002)S(0.104)PVS(0.893)PASVPGQR 158.91 2.7069000000000003e-15 0.0 4182.9 1308.9 4911.2 9711.3 8203.2 4563.2 3683.6 6343.5 3136.0 5552.1 True False 5512.975190275082 1731.9763280654402 4846.074279078924 7472.509823089341 7064.327277539068 4277.862382635756 4011.4332639212485 5363.257834128453 3301.7625577291096 5357.7226689277195 1.0289773343901794 0.3232672601943529 0.904502636387636 1.3947175478914569 1.3185317184312013 0.7984478941855937 0.7487198408356747 1.0010331190214148 0.616262311761261 1.0 12.38740418974724 -11.009673750206161 2.860024330725592 1.0030373131589654 0.9086058570029749 0.009007713538462747 0.2988606801630638 187035893.64401552 206358045.8370885 4588935.452821475 0.08266759694322993 9.779716148707485e-12 11.009673750206161 -0.09443145615599047 RNSSSPVS(ph)PASVPGQR ddPTM_PC-9_Lapatinib_30min_R1 1 RNSSSPVSPASVPGQR 16 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 RNS(0.027)S(0.285)S(0.088)PVS(0.594)PAS(0.006)VPGQR 152.37 6.085100000000001e-11 0.0 10132.0 6902.3 5791.2 6901.1 6052.8 4288.1 4885.3 3486.0 4004.8 4535.5 True False 9987.515822018762 6886.3181484260485 5315.069890678469 7408.629915394732 5696.786204262659 4104.707959049328 5138.236930043516 3647.972286268673 3553.737251586415 5319.455131826129 1.8775448940745407 1.2945532912244015 0.9991756221193739 1.39274225118831 1.0709341583086152 0.7716406769729087 0.9659329391278458 0.685779313080953 0.6680641463304238 1.0 12.37706276368371 -1.5228787452873038 0.3845063336100233 0.7903017970833885 15.563126714073109 0.743641489531593 0.17725411348060516 36.12281499980984 0.49020789402470066 0.1400504239552574 399.1418327785604 0.029999999999518787 1.5228787452873038 14.77282491698972 RNSTT(ph)IMSR ddPTM_PC-9_Lapatinib_30min_R1 1 RNSTTIMSR 9 1 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 RNS(0.246)T(0.14)T(0.615)IMSR 119.27 0.0059575 44157000.0 52170.0 42769.0 52239.0 39208.0 48228.0 48777.0 48891.0 46915.0 50612.0 45392.0 True False 51426.046233193745 42669.97100821952 47944.11106837143 42091.487114053794 45391.32385989616 46690.921414740566 51422.33675449976 49094.842171627846 44911.54359201247 53237.94671896191 0.9659659961092599 0.801495430195125 0.9005627381060329 0.7906294233369062 0.8526122184898053 0.877023331895528 0.9658963187658873 0.9221776044593696 0.8436002205174491 1.0 15.700167310012352 -7.063625892812777 6.16177826294744 0.9262886253463715 0.8576707961316349 0.239502087563088 0.05925229804692655 0.34185176149955565 25.639749465189663 0.021820825746784733 0.017010180427920008 8.63722249523985e-08 7.063625892812777 -0.06861782921473658 RNSVT(ph)PLASPEPTK ddPTM_PC-9_AZD4547_30min_R2 1 RNSVTPLASPEPTK 14 1 Q5W015;Q5VX20;A0A1W2PR17;Q16875-3;Q16875-2;Q16875;Q16875-4;Q9H178 Q5W015 PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3;6-phosphofructo-2-kinase;Fructose-2,6-bisphosphatase 1 RNS(0.021)VT(0.96)PLAS(0.019)PEPTK 103.3 0.004256899999999999 8185600.0 28706.0 29850.0 36597.0 41772.0 30869.0 34473.0 29654.0 45743.0 35703.0 35389.0 True False 37833.91087810767 39498.42875143509 36111.699867945 32142.11077096661 26583.372187725938 32317.397860405523 32293.14855259002 38674.4704195693 37590.18769088089 34150.04188157328 1.1078730447625642 1.1566143575580121 1.0574423303249356 0.9412026750195551 0.7784286847996467 0.9463355263948705 0.9456254450456413 1.1324867639602316 1.1007362105509995 1.0 15.05959972738549 -5.53767725532062 4.081673749574791 0.9729334412188122 1.1293129037047973 0.31406962795245474 0.09176760873632185 0.27039404575855386 10.358145690417741 0.028744369392619176 0.056155486301824147 2.8994975404029597e-06 5.53767725532062 0.1563794624859851 RNSVT(ph)PLASPEPTK ddPTM_PC-9_Lapatinib_30min_R1 1 RNSVTPLASPEPTK 14 1 Q5W015;Q5VX20;A0A1W2PR17;Q16875-3;Q16875-2;Q16875;Q16875-4;Q9H178 Q5W015 PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3;6-phosphofructo-2-kinase;Fructose-2,6-bisphosphatase 1 RNS(0.043)VT(0.954)PLAS(0.002)PEPT(0.001)K 185.86 1.8827e-05 8761000.0 17687.0 28026.0 26454.0 19008.0 29232.0 29813.0 38257.0 33082.0 31924.0 24864.0 True False 17434.78013660144 27961.107518912315 24279.054235393058 20405.911728829193 27512.631232323227 28537.967487497364 40237.76026706136 34619.110491778614 28328.38294537673 29161.709270802552 0.597865508317703 0.9588295137043866 0.832566226140313 0.6997501943159454 0.9434505699523442 0.9786109319754555 1.379814876192749 1.1871427072500222 0.971423954690469 1.0 14.831787663145704 -6.760261219005621 2.297689634816926 1.1486038113442867 0.7946769576608865 0.5459042474385977 0.14215954490513016 0.2242611876924043 2.4308560637550043 0.05475499356019164 0.050580784792198165 1.7367558923500947e-07 6.760261219005621 -0.35392685368340016 RNT(ph)FVGTPFWMAPEVIK ddPTM_PC-9_AZD4547_30min_R2 2 RNTFVGTPFWMAPEVIK 17 1 B4DR80;Q9Y6E0-2;C9JDH9;C9J6L2;C9JCC0;C9J232;H7C279;H0Y630;O00506-3;O00506-2;O00506;Q9Y6E0 B4DR80 STK24;STK25 Serine/threonine-protein kinase 24;Serine/threonine-protein kinase 24 36 kDa subunit;Serine/threonine-protein kinase 24 12 kDa subunit;Serine/threonine-protein kinase 25 1 RNT(0.615)FVGT(0.385)PFWMAPEVIK;RNT(0.847)FVGT(0.153)PFWMAPEVIK 106.42 0.0003037 16201100.0 117939.0 110043.0 130613.0 167999.0 150783.0 148074.0 134957.0 161427.0 131173.0 136535.0 True False 155441.14871640562 145612.24774184814 128880.9862789818 129269.42610867613 129849.3831540342 138814.90937202147 146967.91155364836 136482.16637343008 138106.53698501282 131754.9512080196 1.179774629273623 1.1051747688172275 0.9781870441855329 0.981135243294051 0.9855370288819217 1.0535840065156667 1.115464050543421 1.0358788426701853 1.048207568055375 1.0 17.007497652231294 -4.996339747187191 3.856968561043405 1.027512378835912 1.172269557858842 0.6019281495751778 0.04035608452606219 0.16248844770689955 5.375182514371043 0.011746127325112215 0.04925207274105822 1.0084636595097854e-05 4.996339747187191 0.14475717902293006 RNT(ph)FVGTPFWMAPEVIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RNTFVGTPFWMAPEVIK 17 1 B4DR80;Q9Y6E0-2;C9JDH9;C9J6L2;C9JCC0;C9J232;H7C279;H0Y630;O00506-3;O00506-2;O00506;Q9Y6E0 B4DR80 STK24;STK25 Serine/threonine-protein kinase 24;Serine/threonine-protein kinase 24 36 kDa subunit;Serine/threonine-protein kinase 24 12 kDa subunit;Serine/threonine-protein kinase 25 1 RNT(0.812)FVGT(0.188)PFWMAPEVIK 61.985 0.014015999999999999 10366000.0 56284.0 57129.0 58776.0 55006.0 58537.0 55034.0 59971.0 45231.0 45517.0 44171.0 True False 65811.7695403278 62800.389567592116 60177.442749221314 51924.1921518581 47067.095061370484 52147.920158179964 54290.11272755946 44043.73417620592 46182.60001529611 52178.85264255638 1.2612728376984779 1.2035601855371758 1.1532917973773418 0.995119469329025 0.9020339213626783 0.9994071835080715 1.040461987530963 0.8440916567851942 0.8850827045137093 1.0 15.671177600724882 -5.6854155428818185 2.0037284615868707 0.9431135517756478 1.2355671213855925 0.8132707726057512 0.05698223649547268 0.14248851598599838 1.158985755798937 0.018448500688316914 0.03941111579720547 2.0634048980300606e-06 5.6854155428818185 0.29245356960994473 RNT(ph)FVGTPFWMAPEVIK ddPTM_PC-9_Lapatinib_30min_R1 2 RNTFVGTPFWMAPEVIK 17 1 B4DR80;Q9Y6E0-2;C9JDH9;C9J6L2;C9JCC0;C9J232;H7C279;H0Y630;O00506-3;O00506-2;O00506;Q9Y6E0 B4DR80 STK24;STK25 Serine/threonine-protein kinase 24;Serine/threonine-protein kinase 24 36 kDa subunit;Serine/threonine-protein kinase 24 12 kDa subunit;Serine/threonine-protein kinase 25 1 RNT(0.987)FVGT(0.013)PFWMAPEVIK;RNT(0.726)FVGT(0.274)PFWMAPEVIK 84.37100000000001 0.0083623 4978900.0 37624.0 39900.0 40335.0 38429.0 37460.0 32777.0 36738.0 30911.0 34064.0 28754.0 True False 37087.474860603426 39807.61400144869 37018.81199760261 41255.196855385984 35256.676449193634 31375.204116918845 38640.11387958542 32347.237906153438 30227.3536101777 33724.090587703366 1.0997323934993353 1.180391029312545 1.0976963752760343 1.2233153255266325 1.0454448388312978 0.9303498943974198 1.1457718564447978 0.9591730226803518 0.8963133796467543 1.0 15.041491919170724 -6.474715373351325 6.416621897586873 0.9929378320280341 1.1477774384724233 0.5468407307476458 0.07029891592302277 0.1787503476513164 18.192328754262533 0.022101991009402706 0.024701549034319457 3.3518503978142456e-07 6.474715373351325 0.1548396064443892 RNT(ph)FVGTPFWMAPEVIQQSAYDSK ddPTM_PC-9_AZD4547_30min_R2 1 RNTFVGTPFWMAPEVIQQSAYDSK 24 1 Q8NBY1;B4E0Y9;Q9P289-3;Q9P289;Q9P289-2 Q8NBY1 STK26 Serine/threonine-protein kinase 26 1 RNT(0.682)FVGT(0.318)PFWMAPEVIQQSAYDSK 83.31 1.9667e-05 5888900.0 19392.0 13551.0 25333.0 34109.0 22322.0 25238.0 22262.0 24686.0 18351.0 27872.0 True False 25558.252621342715 17931.09574575199 24997.067867711856 26245.697028796785 19222.975605766915 23659.863870301826 24243.274872791502 20871.34592784663 19320.996395690974 26896.20976357654 0.9502548071272958 0.6666774204756051 0.9293899805006524 0.9758139626178596 0.7147094618439178 0.8796727895222826 0.9013639871898345 0.7759958042902789 0.7183538708809413 1.0 14.71511526086063 -6.257657988912423 24.972645428545466 0.8263660197762625 0.8687482655740836 0.037638060915167304 0.1130939720632042 1520.0578709760273 10038587.303335922 0.03384228072462575 0.041980112227336656 5.525123768180138e-07 6.257657988912423 0.04238224579782113 RNT(ph)FVGTPFWMAPEVIQQSAYDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RNTFVGTPFWMAPEVIQQSAYDSK 24 1 Q8NBY1;B4E0Y9;Q9P289-3;Q9P289;Q9P289-2 Q8NBY1 STK26 Serine/threonine-protein kinase 26 1 RNT(0.978)FVGT(0.022)PFWMAPEVIQQSAYDSK;RNT(0.72)FVGT(0.28)PFWMAPEVIQQSAYDSK 84.971 1.0349e-05 17597500.0 48469.0 41725.0 42299.0 46698.0 45299.0 48213.0 42660.0 48381.0 46496.0 34005.0 True False 56673.84439361363 45867.1822490816 43307.568579850784 44081.66245695871 36422.98613159238 45684.62540586424 38618.93596834613 47111.0500139068 47175.91603821007 40169.837316568104 1.4108557111392241 1.1418314166326886 1.078111624863079 1.09738215043199 0.9067247607838747 1.137286791724734 0.961391395837635 1.1727966345155145 1.174411428814831 1.0 15.293824998188102 -4.640125868191139 1.9385814819000302 1.0654298621697542 1.6180766754958142 0.6039730230761111 0.08372588380162657 0.8563948692967388 2.5120827958277028 0.022476191966343883 0.9667800623945693 2.2902038046211698e-05 4.640125868191139 0.55264681332606 RNT(ph)IDSTSSFSQFR ddPTM_PC-9_AZD4547_30min_R2 1 RNTIDSTSSFSQFR 14 1 Q8TDN4-2;Q8TDN4;Q8TDN4-4 Q8TDN4-2 CABLES1 CDK5 and ABL1 enzyme substrate 1 1 RNT(0.954)IDSTS(0.02)S(0.02)FS(0.006)QFR 112.96 0.00086638 4683600.0 13932.0 11373.0 17064.0 17277.0 15769.0 9015.1 16165.0 16664.0 15029.0 15826.0 True False 18362.086196397813 15049.099838863358 16837.720210580475 13294.05457698913 13579.746542753262 8451.384371866148 17603.653684245557 14088.961700625292 15823.40225768839 15271.936557059491 1.2023417022322485 0.9854087451605392 1.1025268568704993 0.8704891175601381 0.8891961076459547 0.5533931037684592 1.1526798594581789 0.9225393025950356 1.0361097427669697 1.0 13.898595394147929 -4.805940532230028 1.0636638084051528 0.9151584290005047 1.3009226852854845 0.20923950227571808 0.1547008521141654 2.812489644537013 2.6606094923467514 0.05096452922311382 1.224428639723893 1.5633616984783763e-05 4.805940532230028 0.3857642562849798 RNT(ph)IDSTSSFSQFR ddPTM_PC-9_Lapatinib_30min_R1 1 RNTIDSTSSFSQFR 14 1 Q8TDN4-2;Q8TDN4;Q8TDN4-4 Q8TDN4-2 CABLES1 CDK5 and ABL1 enzyme substrate 1 1 RNT(0.426)IDS(0.002)T(0.002)S(0.188)S(0.369)FS(0.012)QFR 95.822 0.010578 3819900.0 10813.0 11335.0 11015.0 11215.0 16510.0 14142.0 16667.0 14191.0 12933.0 15738.0 True False 10658.804637138663 11308.754503920321 10109.389219129607 12039.788512143274 15538.914259908877 13537.17962661215 17529.935707742672 14850.36566679253 11476.349349472399 18458.292330433174 0.5774534526991384 0.6126652618495467 0.5476882172064051 0.6522699010619 0.8418392114361001 0.7333928504476374 0.9497051728257727 0.8045362702544231 0.6217449124776688 1.0 14.171981467724134 -6.125544465723559 3.4817471028859157 0.8173472084671479 0.5836148973975018 0.5605507034451255 0.0999019722436818 0.19244855234178065 4.278101034972918 0.029938982893828698 0.04023894424633374 7.489546720279138e-07 6.125544465723559 -0.2337323110696461 RNT(ph)LDVGEVLSK ddPTM_PC-9_AZD4547_30min_R2 2 RNTLDVGEVLSK 12 1 E7EUN2 E7EUN2 AGAP1 1 RNT(1)LDVGEVLSK;RNT(1)LDVGEVLSK 137.91 5.7578e-05 14167700.0 89421.0 92992.0 101033.0 114691.0 126683.0 130740.0 131754.0 147530.0 133747.0 130045.0 True False 117855.01792765528 123049.84544232674 99693.23640621059 88250.76190828613 109095.25215775329 122564.80713223181 143479.85075868163 124732.62840213953 140816.5933700878 125492.16413261765 0.9391424456040811 0.9805380781567372 0.7944180188083835 0.703237230135138 0.8693391568453914 0.9766729897390863 1.143337129855016 0.9939475445679982 1.1221146303706708 1.0 16.93723775797583 -6.9034133584495265 3.350349442655993 1.0644051362988156 0.8517072327558645 0.5812011253002634 0.08306400590315675 0.18858086115333278 4.191752290719275 0.03386555871559656 0.029287134773521326 1.2490696085510454e-07 6.9034133584495265 -0.21269790354295115 RNT(ph)LDVGEVLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RNTLDVGEVLSK 12 1 E7EUN2 E7EUN2 AGAP1 1 RNT(1)LDVGEVLSK;RNT(1)LDVGEVLSK;RNT(1)LDVGEVLSK 99.915 0.0027139 10433900.0 74691.0 82651.0 86839.0 93777.0 123156.0 105961.0 111634.0 99533.0 104688.0 86029.0 True False 87334.71108550603 90856.04505857028 88909.57109874135 88522.97871913624 99024.46588274329 100404.21862632029 101059.21935982996 96920.36421393092 106218.86394976225 101625.37669481087 0.8593789654308407 0.8940291097903454 0.874875685486942 0.8710715925312418 0.9744068765434609 0.9879837289837772 0.9944289767635389 0.9537023858222984 1.0452001990481767 1.0 16.63290117438512 -6.319325906365029 3.9746492648382046 0.9920887778397703 0.8756233297523495 0.8680223475487032 0.02257228886490094 0.07727732442450395 2.5007212128750123 0.006881785828090945 0.00806122937741211 4.79373578682886e-07 6.319325906365029 -0.11646544808742088 RNT(ph)LDVGEVLSK ddPTM_PC-9_Lapatinib_30min_R1 3 RNTLDVGEVLSK 12 1 E7EUN2 E7EUN2 AGAP1 1 RNT(1)LDVGEVLSK;RNT(1)LDVGEVLSK;RNT(1)LDVGEVLSK 105.0 0.0015649000000000001 14454500.0 90985.0 151975.0 153542.0 134938.0 154077.0 141676.0 133240.0 137323.0 147627.0 123224.0 True False 89687.53721539432 151623.11122481633 140918.3694492597 144861.79065997232 145014.49378703686 135616.84774288666 140138.5152516729 143703.5279022585 130999.69267877225 144523.10421434097 0.6205757737003732 1.0491271416364363 0.9750577266889099 1.0023434761346466 1.0034000762394857 0.9383748604081634 0.9696616746055682 0.9943290983366441 0.9064273383201604 1.0 17.140940622325196 -4.754819348069689 24.999969275036143 0.9812291023761557 0.6205751657985537 0.8958362806727362 0.036979976553746456 64.73618656506251 244448.33653546442 0.008984564457051524 0.08445734604844748 1.7586550032954317e-05 4.754819348069689 -0.36065393657760203 RNT(ph)SASDEDER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RNTSASDEDER 11 1 Q32MZ4-2;Q32MZ4;C9JTC6;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 RNT(0.496)S(0.496)AS(0.009)DEDER 74.678 0.01916 623440.0 2093.5 2791.7 859.05 832.94 756.71 2372.3 728.57 966.18 868.46 735.19 True False 2447.888201490234 3068.8415262974486 879.5330099652674 786.2730722279148 608.4381075881865 2247.8924118045284 659.5545752099841 940.8187987523294 881.159584535098 868.4741272391624 2.8186080905736977 3.5336015547787802 1.0127336927828359 0.905350024332261 0.7005828826730649 2.588323982604376 0.7594406724661753 1.0833008943434472 1.0146066035798464 1.0 9.762339059942693 -5.265214371091764 24.999328551566798 1.1510719069200135 3.176104910688613 0.7042798260073395 0.5294499407950175 156.54137011771613 1036679.2116894753 0.13833284258505005 0.30667756501622845 5.429822451266902e-06 5.265214371091764 2.0250330037685993 RNT(ph)YVCSER ddPTM_PC-9_AZD4547_30min_R2 2 RNTYVCSER 9 1 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;A2SY06;H0YKP9 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 RNT(0.999)Y(0.001)VCSER;RNT(0.997)Y(0.002)VCSER 80.737 0.015494999999999998 55752000.0 30461.0 22637.0 29602.0 42645.0 29197.0 27528.0 25732.0 37643.0 26639.0 26417.0 True False 40146.96437183992 29953.96755933789 29209.45813839679 32813.854108682164 25143.500526905147 25806.669808291812 28022.098150510792 31826.139300086295 28047.083155403623 25492.148870709007 1.5748756440838767 1.175027170571548 1.1458217307038814 1.2872141252237055 0.9863233050468937 1.012337953115604 1.099244253304544 1.2484682818032329 1.1002243591802607 1.0 14.637765370581079 -2.2139253164689356 1.1398510817835172 1.1077662141985989 199.99998648556684 0.6826720942959259 0.09448040004168713 408.4422293301364 1.6615681815804737 0.029815150504153093 211051.91890423532 0.006110470946980195 2.2139253164689356 198.89222027136825 RNT(ph)YVCSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RNTYVCSER 9 1 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;A2SY06;H0YKP9 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 RNT(1)YVCSER;RNT(1)YVCSER 89.805 0.007693600000000001 61903000.0 24313.0 17146.699999999997 23586.0 19165.4 25650.0 19761.1 13234.6 27775.0 16776.4 10997.5 True False 28428.710696361137 18848.911057407466 24148.3796904031 18091.62477306516 20624.066630065656 18724.79312857161 11980.922877793566 27045.935680045095 17021.72311216937 12991.259693837897 2.1882951589248605 1.450891715015751 1.8588174095124375 1.392599732391348 1.5875340125675574 1.441337758604986 0.9222294958414571 2.0818562877989195 1.3102442344558187 1.0 13.665253707636284 -1.522878745280339 0.6182276383648825 1.4164832240032914 48.905171609811255 0.3118771932268559 0.3297809729421885 252.07094040245155 1.8302573547881238 0.13971821048606267 16254.194298268927 0.029999999999999905 1.522878745280339 47.48868838580796 RNT(ph)YVCSER ddPTM_PC-9_Lapatinib_30min_R1 2 RNTYVCSER 9 1 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;A2SY06;H0YKP9 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 RNT(0.98)YVCS(0.019)ER;RNT(0.999)Y(0.001)VCSER 82.505 0.013309 43849000.0 27823.0 29827.3 20448.5 27484.9 23477.4 20789.0 23167.5 25522.7 25334.7 15061.8 True False 27426.23891788668 29758.236719433848 18767.303263492664 29506.23123293862 22096.50549034433 19899.90293152594 24366.9997905519 26708.577817197212 22481.239299781842 17665.21206141303 1.552556449508757 1.6845671943240463 1.0623876576317466 1.6703015582468153 1.2508485838452394 1.1265023517602857 1.3793777117331023 1.5119307780934055 1.2726277624987414 1.0 14.108623447663529 -1.5229006089894637 0.03359696972528319 5.125023823652426e-10 3.418581898250765 0.3072403189796803 0.19583796594658134 1524.9983896156798 3.934393662383209 120.9896070653216 325.26684064447267 0.029998489746494363 1.5229006089894637 3.4185818977382625 RNTFVGT(ph)PFWMAPEVIQQSAYDSK ddPTM_PC-9_AZD4547_30min_R2 1 RNTFVGTPFWMAPEVIQQSAYDSK 24 1 Q8NBY1;B4E0Y9;Q9P289-3;Q9P289;Q9P289-2 Q8NBY1 STK26 Serine/threonine-protein kinase 26 1 RNT(0.455)FVGT(0.545)PFWMAPEVIQQSAYDSK 69.152 0.0004055 6208500.0 8657.6 4161.5 8641.1 10038.0 9125.1 6123.2 7748.6 11012.0 8725.2 10660.0 True False 11410.53671073311 5506.623492432067 8526.513368005559 7723.894185554028 7858.237375691407 5740.31533602631 8438.210388972791 9310.348430586035 9186.396259151164 10286.796644651475 1.1092410110649862 0.5353098425733132 0.8288793550165922 0.7508551449366889 0.7639149141513578 0.5580274923594348 0.820295246466271 0.9050775233733103 0.8930278857925656 1.0 13.328506169908303 -7.662735497177745 3.668051884124407 0.9267196385864723 0.7470172704575451 0.2082267596364542 0.15053160253399187 0.3515088417735921 9.040016826503711 0.0752334128170847 0.03970645916913156 2.1740248443868966e-08 7.662735497177745 -0.17970236812892726 RNTFVGT(ph)PFWMAPEVIQQSAYDSK ddPTM_PC-9_Lapatinib_30min_R1 1 RNTFVGTPFWMAPEVIQQSAYDSK 24 1 Q8NBY1;B4E0Y9;Q9P289-3;Q9P289;Q9P289-2 Q8NBY1 STK26 Serine/threonine-protein kinase 26 1 RNT(0.427)FVGT(0.573)PFWMAPEVIQQSAYDSK 70.345 0.0030912 0.0 11696.0 8661.2 10417.0 10711.0 8563.3 10660.0 7728.0 8685.9 10310.0 6367.5 True False 11529.212895216284 8641.145523542546 9560.554470782852 11498.722670848563 8059.6235300955595 10204.096649673702 8128.118026605595 9089.478623436904 9148.779230886918 7468.11389083957 1.5437917878245109 1.1570720063792577 1.2801832712420043 1.5397090669644127 1.0792046891493632 1.366355253659174 1.0883762815368403 1.217104982100783 1.225045488675375 1.0 12.86652821389955 -1.5228788064999517 0.031060190781115556 3.016298640539445e-10 3.0842257210714905 0.36673253219419066 0.14074917516651503 1451.667866884238 3.468074193600161 108.14402875252955 269.96880680295584 0.029999995771099172 1.5228788064999517 3.0842257207698607 RPAAAAAAGS(ph)ASPR ddPTM_PC-9_Lapatinib_30min_R1 1 RPAAAAAAGSASPR 14 1 Q96S55-2;Q96S55 Q96S55-2 WRNIP1 ATPase WRNIP1 1 RPAAAAAAGS(0.618)AS(0.382)PR 103.39 0.0033431999999999993 0.0 9058.5 8286.5 7048.9 5945.4 8926.1 7382.2 6239.9 8567.9 8197.4 5693.9 True False 8929.324128874545 8267.313118371043 6469.366651540868 6382.644549272995 8401.08434738781 7066.480514748707 6562.971489934813 8965.995912656728 7274.1224895511505 6678.083028355154 1.3371088815398995 1.237976988795739 0.9687460644127849 0.9557599871358702 1.2580083703237575 1.0581600265741555 0.9827627871753649 1.3426002453978323 1.0892530773674438 1.0 12.70521831514781 -5.04260022439153 5.750651783239542 1.09157596449232 1.316262265889346 0.3278106080205673 0.12089030245070816 0.2052219898431943 17.95985512011272 0.03151807286161352 0.09342461419438451 9.065667273328e-06 5.04260022439153 0.22468630139702594 RPAAAAAAGSAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 9 RPAAAAAAGSASPR 14 1 Q96S55-2;Q96S55 Q96S55-2 WRNIP1 ATPase WRNIP1 1 RPAAAAAAGS(0.137)AS(0.863)PR;RPAAAAAAGS(0.062)AS(0.938)PR;RPAAAAAAGS(0.049)AS(0.951)PR;RPAAAAAAGS(0.031)AS(0.969)PR;RPAAAAAAGS(0.011)AS(0.989)PR;RPAAAAAAGSAS(1)PR;RPAAAAAAGS(0.366)AS(0.634)PR;RPAAAAAAGS(0.001)AS(0.999)PR;RPAAAAAAGS(0.018)AS(0.982)PR 139.29 1.0897000000000001e-05 1021497700.0 43620.5 42791.6 48184.5 63800.49999999999 62471.00000000001 46807.1 50340.3 55211.7 47324.799999999996 58592.40000000001 True False 57490.911637235935 56623.14786465361 47545.54204680701 49092.28043289892 53797.97997795293 43880.244637594245 54820.489177916905 46680.0004036494 49826.29231250594 56541.097910138575 1.0167986431499245 1.0014511560183257 0.840902348984657 0.868258350959542 0.9514845301280616 0.7760769822215626 0.9695688835940849 0.8255941629898745 0.8812402686572419 1.0 15.787012277117789 -5.241957820458413 18.734995728040168 0.8832272046020045 1.0091263649649054 0.3476896788656815 0.06533739628032557 32.048176900930095 30814.797737403835 0.015313709759262209 0.040139968456319036 5.728516647741946e-06 5.241957820458413 0.12589916036290083 RPAAAAAAGSAS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 9 RPAAAAAAGSASPR 14 1 Q96S55-2;Q96S55 Q96S55-2 WRNIP1 ATPase WRNIP1 1 RPAAAAAAGS(0.004)AS(0.996)PR;RPAAAAAAGS(0.203)AS(0.797)PR;RPAAAAAAGS(0.007)AS(0.993)PR;RPAAAAAAGS(0.039)AS(0.961)PR;RPAAAAAAGS(0.003)AS(0.997)PR;RPAAAAAAGS(0.028)AS(0.972)PR;RPAAAAAAGS(0.14)AS(0.86)PR;RPAAAAAAGS(0.004)AS(0.996)PR;RPAAAAAAGS(0.046)AS(0.954)PR 151.39 1.0457999999999999e-05 817937100.0 66156.1 75990.9 89535.3 90608.29999999999 106413.2 87514.4 90873.9 80135.3 86635.70000000001 75420.2 True False 77355.02108746505 83534.77434563781 91670.16111651629 85531.81070707201 85562.29735354801 82924.9908037036 82265.66632193829 78031.83328536892 87902.58321385812 89093.2852340254 0.8682474878356218 0.9376102152503771 1.0289233456339846 0.9600253316779339 0.9603675196037234 0.9307658886512123 0.9233655051090248 0.8758441568340323 0.9866353337735878 1.0 16.44302908262526 -7.522362293158656 0.003534903290990065 1.8963290623928075 3.2206395569786246e-08 0.07065371640444096 0.0468469478065111 56196.25988510166 154.57076435481977 41315.15870310975 41597.761559184764 3.003569646916583e-08 7.522362293158656 -1.896329030186412 RPAAAAAAGSAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 6 RPAAAAAAGSASPR 14 1 Q96S55-2;Q96S55 Q96S55-2 WRNIP1 ATPase WRNIP1 1 RPAAAAAAGS(0.098)AS(0.902)PR;RPAAAAAAGS(0.154)AS(0.846)PR;RPAAAAAAGS(0.011)AS(0.989)PR;RPAAAAAAGS(0.013)AS(0.987)PR;RPAAAAAAGS(0.001)AS(0.999)PR;RPAAAAAAGS(0.006)AS(0.994)PR 145.33 6.823099999999999e-06 549768900.0 46743.3 50412.3 49854.5 47408.8 57475.100000000006 46078.2 49505.799999999996 46774.5 51704.9 42665.6 True False 46076.73197032864 50295.573416672494 45755.655453935266 50895.401303120634 54094.52761839424 44107.542799530485 52068.968090260234 48947.814028707435 45881.34968526527 50040.292111661525 0.9207926258206394 1.0051015150839113 0.9143762660664454 1.0170884132640752 1.0810194212632884 0.8814405539661417 1.0405408500428386 0.9781680314631997 0.9168881265298 1.0 15.610802590852051 -4.746824955945062 23.966458419277103 0.9817657185303524 0.920792354943796 0.08859723688236598 0.05853125614099047 1200.075619965975 1967834.886171984 0.014124324407536483 0.28807982436850565 1.791327710049145e-05 4.746824955945062 -0.06097336358655647 RPAEATSSPTS(ph)PERPR ddPTM_PC-9_AZD4547_30min_R2 1 RPAEATSSPTSPERPR 16 2 Q9BU76 Q9BU76 MMTAG2 Multiple myeloma tumor-associated protein 2 1 RPAEATSSPT(0.26)S(0.74)PERPR 89.604 0.010444 30871000.0 26115.0 36075.0 45286.0 60784.0 51949.0 33742.0 38571.0 51530.0 33001.0 38759.0 True False 34419.02677425562 47735.538264925344 44685.47805065323 46771.187903438535 44736.778055012335 31632.10740596416 42003.7442780721 43567.22254159994 34745.36548712319 37402.05920732146 0.9202441657949701 1.2762810197247403 1.1947330975270487 1.250497670306962 1.1961046798796335 0.8457317077283321 1.1230329337014113 1.1648348637732666 0.9289693194304602 1.0 15.190830080849766 RPAEATSSPTS(ph)PERPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPAEATSSPTSPERPR 16 2 Q9BU76 Q9BU76 MMTAG2 Multiple myeloma tumor-associated protein 2 1 RPAEATSSPT(0.053)S(0.947)PERPR;RPAEATSSPT(0.012)S(0.988)PERPR 97.713 0.0060456 44387900.0 73033.9 83089.9 67574.0 89330.0 97515.0 81864.2 68064.1 64979.7 72323.0 70757.4 True False 85397.09678472296 91338.51614998106 69185.22043582225 84325.12971176759 78407.63576728456 77571.0972383122 61616.575706589516 63274.0517266832 73380.58705332648 83585.15650472986 1.0216777757650135 1.092760006315385 0.8277213721781719 1.00885292602157 0.9380569355379227 0.9280487168068251 0.7371712668038469 0.7570010558406107 0.8779140952996131 1.0 16.350959143167024 -7.044077277911188 4.434511877140064 0.8224483736869054 0.9748616923979793 0.3071078585578335 0.09311740445290588 0.23668146039101517 10.235430942688017 0.035748708722457716 0.02834924817146787 9.034886935739834e-08 7.044077277911188 0.1524133187110739 RPAETNLR ddPTM_PC-9_AZD4547_30min_R2 2 RPAETNLR 8 1 A0A2R8YDT1;P15104 A0A2R8YDT1 GLUL Glutamine synthetase 0 ; 110.41 0.0023808 2318800.0 6124.9 4937.2 6677.5 8346.7 7021.6 8815.1 4426.3 9409.8 6321.799999999999 7417.5 False True 8072.490794165731 6533.0533477918025 6588.951986999008 6422.497270229508 6046.772041638426 8263.890403482746 4820.232125120702 7955.731625692741 6655.95744178951 7157.815582711288 1.1277869205884146 0.9127160754981573 0.9205255305702076 0.8972705703318427 0.8447789652814703 1.1545268675883504 0.6734222290894593 1.1114747975497872 0.9298866902726655 1.0 12.805303658629395 RPAETNLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPAETNLR 8 1 A0A2R8YDT1;P15104 A0A2R8YDT1 GLUL Glutamine synthetase 0 101.25 0.0029378 542520.0 1295.6 2627.7 3194.3 2804.8 3730.9 4016.9 2353.2 2918.0 2232.3 3665.0 False True 1514.9194907335782 2888.560690135688 3270.464226450209 2647.656149284289 2999.8569274897445 3806.246692651692 2130.2878603073623 2841.4055918765644 2264.9431644033116 4329.435487875964 0.3499115519739048 0.6671910687258735 0.7554020000087147 0.6115476617445195 0.6928979392095029 0.8791554241449269 0.4920474889331331 0.6562993258205512 0.5231497664640109 1.0 12.079963209859972 -11.750658942764973 2.2926854416857347 2.210376632681332 0.6363925749256523 0.39236174630430953 0.13927771741268852 17568459.35847041 2868557.2443075674 110443445.33810054 0.03418413760642692 1.775583322725144e-12 11.750658942764973 -1.5739840577556796 RPAETNLR ddPTM_PC-9_Lapatinib_30min_R1 2 RPAETNLR 8 1 A0A2R8YDT1;P15104 A0A2R8YDT1 GLUL Glutamine synthetase 0 ; 110.41 0.0023808 1737460.0 6341.4 6099.1 6184.1 6601.4 8224.0 6122.6 7009.7 7723.4 6323.0 7001.8 False True 6250.970473129666 6084.97790867759 5675.667169316329 7086.888977624838 7740.280489006101 5860.750670477697 7372.627967274486 8082.257359657905 5610.837155858191 8212.05180068795 0.7611947202532261 0.7409814326996612 0.6911387442588781 0.8629863948290178 0.9425513473207356 0.7136767780722868 0.8977814736454606 0.9841946392716164 0.6832442478490154 1.0 13.003527012493395 -1.5228788364919161 0.05754945753499597 1.223432101135661 0.028165872149234696 0.2738516766318585 0.10009909442134644 489.87641174325 2.11999064370292 9.269724325397924 49.70488347585685 0.02999999369932803 1.5228788364919161 -1.1952662289864264 RPAS(ph)LSTAPSEK ddPTM_PC-9_AZD4547_30min_R2 2 RPASLSTAPSEK 12 1 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 RPAS(0.981)LS(0.009)T(0.009)APSEK;RPAS(0.986)LS(0.007)T(0.007)APSEK 111.66 0.00082505 0.0 18158.699999999997 21442.7 23839.0 32131.0 28063.0 20680.0 24314.0 28691.0 18769.199999999997 21766.0 True False 23932.78887557629 28373.633440147318 23522.879283874106 24723.69436900143 24166.936852640298 19386.876330844032 26477.898897540777 24257.465203591 19761.30159391876 21003.97896505479 1.1394407181322304 1.3508694465631361 1.1199249115136765 1.1770957498165129 1.15058850957944 0.9230097003571942 1.2606134743132804 1.1548985667881868 0.9408360971412357 1.0 14.35837503550695 -4.3928626249600216 0.16201417267197638 0.9616836680870198 1.5217563489478034 0.27889024464801393 0.10879451541729836 33.96149757587955 0.8433591691516504 0.40737113841428085 4.026584777673995 4.047038864631882e-05 4.3928626249600216 0.5600726808607837 RPAS(ph)LSTAPSEK ddPTM_PC-9_Lapatinib_30min_R1 1 RPASLSTAPSEK 12 1 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 RPAS(0.731)LS(0.248)T(0.021)APSEK 54.858999999999995 0.0381 5187000.0 30025.0 25658.0 25363.0 19113.0 39865.0 54813.0 54693.0 57715.0 55412.0 54009.0 True False 29596.83799408934 25598.59047742282 23277.75204401128 20518.633779098913 37520.21907760555 52468.775765343766 57524.73592509568 60396.649598966265 49170.91704577168 63344.38368753113 0.46723697147463533 0.40411776052154896 0.3674793357977422 0.3239219104303615 0.5923211639833371 0.8283098312893027 0.9081268547635897 0.9534649495824978 0.7762474616269825 1.0 15.950929090701825 -6.645662615174425 2.3347455984098224 0.9026182445250129 0.39034659061425014 0.9306385852894947 0.06508997356647839 0.0699829209799144 0.7782648871110218 0.023912429966105576 0.023748839735656713 2.2611917112945917e-07 6.645662615174425 -0.5122716539107628 down RPAS(ph)MGSEGLGGDADPMK ddPTM_PC-9_AZD4547_30min_R2 1 RPASMGSEGLGGDADPMK 18 1 Q6DT37 Q6DT37 CDC42BPG Serine/threonine-protein kinase MRCK gamma 1 RPAS(0.673)MGS(0.327)EGLGGDADPMK 51.39 0.02041 3767300.0 18892.0 21118.0 29520.0 40576.0 36421.0 35279.0 27801.0 41439.0 27768.0 35357.0 True False 24899.263021988787 27943.9805150019 29128.545511974633 31221.830092950804 31364.572822221864 33072.998552990655 30275.23514232671 35035.55472348844 29235.75979050444 34119.16219183321 0.7297735765607015 0.8190113332176308 0.8537297999347377 0.9150819682326223 0.9192656210570527 0.9693379446728336 0.8873381758938211 1.026858588335284 0.8568721478601351 1.0 15.058294600750571 -3.459275096720069 0.48403862028347233 0.9550359788098522 1.6509885208971178e-07 0.6917400126667905 0.0468308040959646 8.0278915393385 0.5341994105670878 0.02558990793862625 5.764120268041007 0.00034731609006664367 3.459275096720069 -0.9550358137110001 RPAS(ph)PALLLPPCMLK ddPTM_PC-9_AZD4547_30min_R2 3 RPASPALLLPPCMLK 15 1 Q9HAW0-2;Q9HAW0 Q9HAW0-2 BRF2 Transcription factor IIIB 50 kDa subunit 1 RPAS(1)PALLLPPCMLK;RPAS(1)PALLLPPCMLK;RPAS(1)PALLLPPCMLK 112.82 0.00012784 4308100.0 54528.0 54474.0 62611.0 81109.0 69173.0 67339.0 58031.0 73013.0 50981.0 64434.0 True False 71866.7697471418 72081.65520287018 61780.73723069934 62410.573171558215 59569.52296289383 63128.28168485042 63195.64657905691 61730.51852182871 53675.75158022571 62178.18527218321 1.155819672648005 1.1592756348120297 0.9936079182796337 1.0037374506566528 0.9580453772031133 1.0152802210052962 1.0163636378646272 0.9928002602778635 0.8632569661732915 1.0 15.924120890454427 -5.275560441204944 5.05696034764787 0.9819250593255858 1.1596859215684199 0.7371186791610566 0.0423460851759888 0.08354690192247438 6.6937841196196315 0.011208166267701672 0.026616105245392117 5.301997990488541e-06 5.275560441204944 0.17776086224283405 RPAS(ph)PALLLPPCMLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPASPALLLPPCMLK 15 1 Q9HAW0-2;Q9HAW0 Q9HAW0-2 BRF2 Transcription factor IIIB 50 kDa subunit 1 RPAS(1)PALLLPPCMLK 87.083 0.0019635 4107800.0 30596.0 31250.0 34291.0 32901.0 42365.0 36394.0 34103.0 30600.0 31471.0 28532.0 True False 35775.29850145461 34352.29347594486 35108.627489341685 31057.6636364812 34063.882369697145 34485.434572024606 30872.51695566122 29796.782423380006 31931.203837717418 33704.62574081227 1.061435862737826 1.0192159895236084 1.0416560551458471 0.9214659102081079 1.0106589710162501 1.02316622166989 0.9159726974294301 0.8840561723638921 0.9473834269298101 1.0 15.040658985062215 -5.3884512014804296 0.5105067254767696 0.9384908691915699 1.0938572368269115 0.38163625243512045 0.04510909825143835 2.6959625967334397 0.8377976815113148 0.032680261939454384 0.23406750461112585 4.088356874299338e-06 5.3884512014804296 0.15536636763534162 RPAS(ph)PALLLPPCMLK ddPTM_PC-9_Lapatinib_30min_R1 2 RPASPALLLPPCMLK 15 1 Q9HAW0-2;Q9HAW0 Q9HAW0-2 BRF2 Transcription factor IIIB 50 kDa subunit 1 RPAS(1)PALLLPPCMLK;RPAS(1)PALLLPPCMLK 92.633 0.0016180999999999997 4776600.0 32981.0 31120.0 28891.0 28903.0 28381.0 28528.0 26662.0 28872.0 32325.0 24156.0 True False 32510.684892025336 31047.943552007106 26515.693502485105 31028.62303758152 26711.685379192844 27307.923942016063 28042.42790183208 30213.498522417973 28684.218102659503 28331.332414153225 1.1475169757912365 1.095887164717208 0.9359141008574274 1.095205216048393 0.9428319497549904 0.9638771499632716 0.989802650009612 1.0664340836763644 1.0124556686338546 1.0 14.790110832380488 -5.062197606991108 5.429779782894588 1.002947516200338 1.1367682721757502 0.5199126635732341 0.04756534779952635 0.14352391149093055 8.544479254252222 0.012080226332374008 0.03526296045401393 8.665674918428163e-06 5.062197606991108 0.1338207559754121 RPAS(ph)PS(ph)SPEHLPATPAESPAQR ddPTM_PC-9_AZD4547_30min_R2 1 RPASPSSPEHLPATPAESPAQR 22 1 Q9H7L9 Q9H7L9 SUDS3 Sin3 histone deacetylase corepressor complex component SDS3 2 RPAS(0.667)PS(0.667)S(0.667)PEHLPATPAESPAQR 66.76 0.0020063 3250400.0 2994.1 3112.5 4671.6 7106.4 5279.0 6007.4 4832.8 5684.5 6053.8 5224.5 True False 3946.161518851187 4118.554756745115 4609.651531630784 5468.129272785528 4546.1019721729 5631.756328332321 5262.909837625859 4806.091141814957 6373.791508922353 5041.591845214035 0.7827213388162836 0.8169155463576141 0.9143246167391971 1.0846037205444157 0.9017195583749006 1.1170591553694547 1.0438984350988112 0.9532884234524781 1.2642418713393015 1.0 12.299663610569644 -5.046148637795713 0.6640571656597033 1.0689866719463332 0.6303047055873618 0.5416079612082288 0.09358269882320866 1.8527816923353044 0.7813021242184771 0.042963450985847765 0.5838465633536793 8.991897801036525e-06 5.046148637795713 -0.4386819663589714 RPAS(ph)PS(ph)SPEHLPATPAESPAQR ddPTM_PC-9_Lapatinib_30min_R1 1 RPASPSSPEHLPATPAESPAQR 22 1 Q9H7L9 Q9H7L9 SUDS3 Sin3 histone deacetylase corepressor complex component SDS3 2 RPAS(0.887)PS(0.575)S(0.538)PEHLPATPAESPAQR 56.332 0.009124700000000001 8978200.0 7801.2 6498.9 8464.3 5369.4 9776.2 10322.0 6749.1 8236.1 9814.3 8116.3 True False 7689.9534574351355 6483.852196341225 7768.397927142871 5764.283587793317 9201.183136748716 9880.552121757219 7098.5353744000795 8618.779273361282 8708.91018483933 9519.191640710047 0.8078368151081297 0.6811347476830067 0.8160774801423598 0.6055433912204915 0.9665929087296313 1.03796125707794 0.7457077914097537 0.9054108372502939 0.9148791739410471 1.0 13.216623351319848 -6.276806653838634 24.9417564289579 0.9200367956249711 0.730642104007098 0.5327299581772552 0.09190092366756003 657.5945981179657 1067302.206483 0.028406956862540213 0.03232505333987626 5.286805658582067e-07 6.276806653838634 -0.18939469161787315 RPAS(ph)PSHNGSSGGGYGASK ddPTM_PC-9_AZD4547_30min_R2 2 RPASPSHNGSSGGGYGASK 19 1 K7ELX9;K7EQ79;K7ENM4;K7ENP7;Q6PI98;Q6PI98-3;Q6PI98-4 K7ELX9 INO80C INO80 complex subunit C 1 RPAS(0.851)PS(0.148)HNGS(0.001)SGGGYGASK;RPAS(0.808)PS(0.187)HNGS(0.004)S(0.001)GGGYGASK 92.56299999999999 0.00039916 6399700.0 4882.0 3140.3999999999996 13080.2 20036.5 14343.3 15543.4 8004.0 17242.1 12361.2 12416.3 True False 6434.374448091739 4155.472886130879 12906.748001549142 15417.394485839126 12351.98037837991 14571.46874085305 8716.340494197431 14577.729629041727 13014.587796110036 11981.60911622759 0.5370208947458639 0.34682093580425777 1.0772132420902103 1.2867549205021382 1.0309116462204313 1.2161529056325013 0.727476619345914 1.216675447148248 1.0862136854793072 1.0 13.548534052960774 -5.267177261265203 24.589028229305566 1.0857917023562083 0.4419208906045811 0.737891263995762 0.1521296670664207 155.8717592947796 667973.9292191397 0.03883177699654409 0.08456601539876839 5.4053365415954295e-06 5.267177261265203 -0.6438708117516272 RPAS(ph)PSHNGSSGGGYGASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPASPSHNGSSGGGYGASK 19 1 K7ELX9;K7EQ79;K7ENM4;K7ENP7;Q6PI98;Q6PI98-3;Q6PI98-4 K7ELX9 INO80C INO80 complex subunit C 1 RPAS(0.5)PS(0.5)HNGSSGGGYGASK;RPAS(0.963)PS(0.037)HNGSSGGGYGASK 81.878 0.00092879 4240900.0 10508.9 14511.8 30038.0 24931.9 31690.0 24038.0 25642.0 18139.5 23474.0 16062.1 True False 12287.849209763888 15952.435598854936 30754.21983974937 23535.046473310395 25480.571988568456 22777.404963519475 23213.004127996526 17663.357345388937 23817.262841555024 18974.031582486357 0.6476140379731405 0.8407509774348404 1.6208584720675023 1.2403819594689618 1.342918181504865 1.2004515152459088 1.2234091646301926 0.9309227334528517 1.2552557814618126 1.0 14.211738633211377 -5.04508110953233 9.332021606332388 1.2283984973221702 0.6949347280598077 0.555144813850512 0.17655694393228336 0.28251886498739104 57.631898384085524 0.04529353138362754 0.12233849751497729 9.014027744601206e-06 5.04508110953233 -0.5334637692623625 RPAS(ph)PSHNGSSGGGYGASK ddPTM_PC-9_Lapatinib_30min_R1 2 RPASPSHNGSSGGGYGASK 19 1 K7ELX9;K7EQ79;K7ENM4;K7ENP7;Q6PI98;Q6PI98-3;Q6PI98-4 K7ELX9 INO80C INO80 complex subunit C 1 RPAS(0.983)PS(0.015)HNGS(0.001)SGGGYGASK;RPAS(0.997)PS(0.003)HNGSSGGGYGASK 97.352 0.00027955 5042300.0 5729.0 7912.5 15625.3 7850.1 12241.0 15483.0 9271.5 10999.5 14134.2 8951.7 True False 5647.303409430071 7894.179092392546 14340.648149402243 8427.42254116593 11521.008446731954 14820.828182635827 9751.532904202095 11510.576925648955 12542.257556275634 10498.98941760952 0.5378901896936941 0.7518989474503105 1.365907477280553 0.8026889261390209 1.0973445146452137 1.411643310905473 0.9288068133344579 1.0963509408193841 1.1946156965582826 1.0 13.357962847215216 -5.055610379705384 5.302123442753481 1.1075721000494214 0.5812495267463846 0.5464881664197574 0.1750369241506694 0.12965882543056148 7.8924400641032 0.04369945335373845 0.1299142976396961 8.798114715601408e-06 5.055610379705384 -0.5263225733030368 RPAS(ph)PSS(ph)PEHLPATPAESPAQR ddPTM_PC-9_Lapatinib_30min_R1 1 RPASPSSPEHLPATPAESPAQR 22 1 Q9H7L9 Q9H7L9 SUDS3 Sin3 histone deacetylase corepressor complex component SDS3 2 RPAS(0.959)PS(0.275)S(0.767)PEHLPATPAESPAQR 72.76899999999999 0.00095975 7751300.0 17582.0 13627.0 18909.0 15139.0 24228.0 25354.0 17113.0 16368.0 20357.0 14300.0 True False 17331.277455856085 13595.44751874039 17354.375010850803 16252.372562223547 22802.956674080695 24269.668523060696 17999.027405447912 17128.51703432176 18064.180291286604 16771.73594644773 1.0333621702127302 0.8106165970028832 1.034739341608015 0.9690334151525809 1.3596062296050149 1.4470576331844192 1.0731761734693972 1.0212727584677719 1.0770608569658893 1.0 14.033744401291107 -6.117491173177661 9.648929101284697 1.1737262873293142 0.9541679896185309 0.30890635697000124 0.14680573645924092 0.47703743469869486 36.44420164672782 0.047200699221645374 0.061003315253900965 7.629723980437278e-07 6.117491173177661 -0.21955829771078328 RPAS(ph)PSSPEHLPATPAESPAQR ddPTM_PC-9_AZD4547_30min_R2 2 RPASPSSPEHLPATPAESPAQR 22 1 Q9H7L9 Q9H7L9 SUDS3 Sin3 histone deacetylase corepressor complex component SDS3 1 RPAS(0.886)PS(0.102)S(0.012)PEHLPATPAESPAQR;RPAS(0.957)PS(0.021)S(0.021)PEHLPATPAESPAQR 89.882 9.4484e-05 19754600.0 14595.5 10273.7 45741.0 78254.0 52515.0 42457.0 25129.4 52893.0 35811.0 40346.0 True False 19236.56539474047 13594.472611846528 45134.44445336154 60213.749312247935 45224.198724883485 39802.157078271026 27365.867917901687 44719.60221022407 37703.89635039451 38933.49882036664 0.49408776445947267 0.3491716137450014 1.1592701868795592 1.5465794530839674 1.1615755093972209 1.0223113330222964 0.7028874554574126 1.1486150375683841 0.9684178790186484 1.0 15.248724380129174 -5.261954366846312 24.999200773405388 1.096819274375254 0.421629640247976 0.6343175649551676 0.20252296307193346 29.01305746806289 1408476.9909341147 0.05789636739901345 0.13362150435023465 5.470734431890835e-06 5.261954366846312 -0.6751896341272781 RPAS(ph)PSSPEHLPATPAESPAQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RPASPSSPEHLPATPAESPAQR 22 1 Q9H7L9 Q9H7L9 SUDS3 Sin3 histone deacetylase corepressor complex component SDS3 1 RPAS(0.522)PS(0.239)S(0.239)PEHLPATPAESPAQR;RPAS(0.79)PS(0.105)S(0.105)PEHLPATPAESPAQR;RPAS(0.448)PS(0.276)S(0.276)PEHLPAT(0.001)PAESPAQR;RPAS(0.37)PS(0.315)S(0.315)PEHLPATPAESPAQR;RPAS(0.828)PS(0.122)S(0.049)PEHLPATPAESPAQR 81.682 0.00018599 34873600.0 38178.7 46650.5 61965.700000000004 73285.4 84227.0 69001.5 66310.4 45666.1 54647.100000000006 55291.399999999994 True False 44641.59984630292 51281.65333758608 63443.19729422594 69179.45663247252 67723.32397857842 65382.93986980151 60028.998866278045 44467.41326223245 55446.21045534387 65315.29313351845 0.6834785194188124 0.7851400625693495 0.9713375574160626 1.059161695731119 1.0368677951140393 1.0010356952106878 0.919064984422039 0.6808116618466602 0.8489008897502754 1.0 15.99513320814651 -10.600665648100431 20.812013682798977 0.9999999999999989 0.8944357658030455 0.060809055424034475 0.13017785416605257 0.0 0.0 0.1411883672716902 0.03424320890409873 2.5080393835177668e-11 10.600665648100431 -0.10556423419695338 RPAS(ph)PSSPEHLPATPAESPAQR ddPTM_PC-9_Lapatinib_30min_R1 2 RPASPSSPEHLPATPAESPAQR 22 1 Q9H7L9 Q9H7L9 SUDS3 Sin3 histone deacetylase corepressor complex component SDS3 1 RPAS(0.769)PS(0.116)S(0.116)PEHLPATPAESPAQR;RPAS(0.874)PS(0.063)S(0.063)PEHLPATPAESPAQR 68.565 0.0010279000000000002 12732000.0 25056.0 21277.1 48617.0 19887.9 27021.0 43773.0 31432.0 32916.0 47573.0 19597.4 True False 24698.696845292354 21227.834182211125 44619.897927047125 21350.522510089548 25431.67790532997 41900.93082984679 33059.39516204282 34445.39752576583 42214.82777410117 22984.784478105932 1.074567258562681 0.9235602884347955 1.9412798048878654 0.9288980947559855 1.106457096848344 1.8229855872592304 1.4383165173262085 1.49861738136273 1.8366423150198663 1.0 14.488391518019784 -6.741194273614373 24.946889815126664 1.5454138027661537 1.2065569456233185 0.17779920943803162 0.34604000966213594 407.69376287707536 502376.6979509284 0.11217652906378886 0.11204697533624829 1.8147037069970902e-07 6.741194273614373 -0.3388568571428352 RPAS(ph)TAGLPTAGLPTATGLPSGAPPGVATIR ddPTM_PC-9_Lapatinib_30min_R1 1 RPASTAGLPTAGLPTATGLPSGAPPGVATIR 31 1 A0A087WXN9;Q765P7 A0A087WXN9 MTSS1L MTSS1-like protein 1 RPAS(0.471)T(0.471)AGLPT(0.057)AGLPTATGLPSGAPPGVATIR 75.156 7.2494e-07 3700200.0 5742.3 3828.4 4685.1 3943.5 5317.1 6125.0 5376.2 5109.1 4075.6 4260.8 True False 5660.413748991151 3819.5355750161957 4299.909163008998 4233.518145130361 5004.358631820806 5863.048028072363 5654.553330051368 5346.487437686539 3616.56301002936 4997.2736028408735 1.1327003880222393 0.7643238850970353 0.8604510188444686 0.8471655709872821 1.0014177788816496 1.1732493543558051 1.1315276647724153 1.0698808715710788 0.723707224670148 1.0 12.286925493061245 -6.387603179814855 5.368171889897444 1.0364329981138878 0.8892819402117266 0.1274311547884247 0.14343631496168024 0.4062162770005399 16.09428161127854 0.0457586047267923 0.051909970899723025 4.0963477709713034e-07 6.387603179814855 -0.1471510579021612 RPAS(ph)VSSSAAVEHEQR ddPTM_PC-9_AZD4547_30min_R2 4 RPASVSSSAAVEHEQR 16 1 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 RPAS(0.996)VS(0.003)S(0.001)SAAVEHEQR;RPAS(0.989)VS(0.009)S(0.002)SAAVEHEQR;RPAS(0.999)VSSSAAVEHEQR;RPAS(0.958)VS(0.033)S(0.008)S(0.001)AAVEHEQR 126.29 1.3146e-05 160136000.0 201841.7 172057.7 152261.2 203012.3 189906.59999999998 162949.7 165176.59999999998 171479.7 181810.40000000002 172035.4 True False 266023.16203183145 227671.98675329288 150242.11700229943 156210.95074376842 163541.34661652744 152760.42949942636 179876.99741052592 144981.45257649483 191420.52657071193 166012.49300950003 1.602428571544964 1.3714147810566546 0.9050048841426763 0.9409590080357946 0.9851146962004168 0.920174299717821 1.0835148255994957 0.8733165194272355 1.1530489248165072 1.0 17.340932287844346 -5.083698632724788 3.259368849637603 0.9783421423158216 1.5775322854323395 0.8629557709696006 0.08250459645155638 0.07644629718350593 1.502440504273879 0.020468889720540347 0.07724828307622054 8.247102025313361e-06 5.083698632724788 0.5991901431165179 RPAS(ph)VSSSAAVEHEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPASVSSSAAVEHEQR 16 1 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 RPAS(0.623)VS(0.355)S(0.02)S(0.002)AAVEHEQR;RPAS(0.923)VS(0.054)S(0.02)S(0.003)AAVEHEQR 123.58 1.7872e-05 90593000.0 155053.0 96094.0 104268.0 97743.0 130766.0 126494.0 147903.0 157848.0 121237.0 120911.0 True False 181300.41046365627 105633.5772568783 106754.14455859188 92266.77659708136 105143.34101158522 119860.43196003967 133892.55711500943 153704.65725378066 123009.86176712983 142831.20716905055 1.2693333204771893 0.7395693094706796 0.7474147049127787 0.6459847145860589 0.7361370326243959 0.8391753758558983 0.9374180878870427 1.0761279716123986 0.8612253876811333 1.0 17.123951702467686 -7.283679998082755 3.409651968458693 0.980214423158207 0.8072256761819081 0.13946701575277298 0.16652465541047495 0.44631195788411 10.948608938771692 0.07447465329445789 0.05058896127792369 5.203792872317276e-08 7.283679998082755 -0.17298874697629885 RPAS(ph)VSSSAAVEHEQR ddPTM_PC-9_Lapatinib_30min_R1 1 RPASVSSSAAVEHEQR 16 1 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 RPAS(0.886)VS(0.105)S(0.008)SAAVEHEQR 109.12 0.00032953 51043000.0 55629.0 62876.0 65961.0 86764.0 85512.0 72263.0 92268.0 74714.0 87020.0 94344.0 True False 54835.72025889083 62730.41448508996 60537.9411968232 93144.91399621933 80482.35228306045 69172.47994328062 97045.18556920858 78185.48519686694 77218.89123877592 110651.23469452208 0.4955726017000833 0.5669201492262743 0.5471058805981873 0.8417882932202887 0.7273515971624746 0.625139702545995 0.877036626271039 0.7065938795234935 0.6978583786430964 1.0 16.755660023883244 -4.720248915595204 0.10556046655842477 1.1305782794913126 1.1530037912935951e-19 0.6035411165459091 0.09549004055778626 40.03375186962223 0.6757423551497732 1.58782414252917 7.058545679251829 1.9043689173246842e-05 4.720248915595204 -1.1305782794913126 RPASMGS(ph)EGLGGDADPMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPASMGSEGLGGDADPMK 18 1 Q6DT37 Q6DT37 CDC42BPG Serine/threonine-protein kinase MRCK gamma 1 RPAS(0.377)MGS(0.623)EGLGGDADPMK 70.167 0.014946000000000001 0.0 8304.0 9466.6 8252.1 11840.0 14809.0 11784.0 11087.0 12450.0 9676.4 9486.1 True False 9709.703188523958 10406.381485420148 8448.86136026353 11176.64318579792 11907.28275729599 11166.026295453588 10036.759097071115 12123.200691865388 9817.899044049724 11205.854838073714 0.8664848268008668 0.9286557461071845 0.7539684818651363 0.9973931794853756 1.0625947711582933 0.9964457381256804 0.8956709900408129 1.0818630855965439 0.8761401237049596 1.0 13.451965088514536 -5.793523666361118 24.994848594430543 0.9902874947241794 0.8575982538227906 0.4328818192831487 0.07186540863874903 172.49847667073627 134382.01907389626 0.019524942280154854 0.028962833387883778 1.608704711050792e-06 5.793523666361118 -0.13268924090138878 RPASPS(ph)SPEHLPATPAESPAQR ddPTM_PC-9_AZD4547_30min_R2 1 RPASPSSPEHLPATPAESPAQR 22 1 Q9H7L9 Q9H7L9 SUDS3 Sin3 histone deacetylase corepressor complex component SDS3 1 RPAS(0.185)PS(0.408)S(0.408)PEHLPATPAESPAQR 48.59 0.021557 14544000.0 2657.1 7166.2 9341.3 15289.0 12741.0 11025.0 8939.5 12522.0 8374.8 9820.1 True False 3502.0025288866373 9482.53400732108 9217.428258503005 11764.357262695312 10972.132075668678 10335.605007135171 9735.098181893793 10587.012626934113 8817.474830506939 9476.301288005812 0.3695537343582706 1.0006577164577022 0.9726820600532758 1.2414503196078728 1.157849644307547 1.090679231591864 1.0273099056290602 1.1172093736966902 0.9304764129510369 1.0 13.210108352784546 -4.64533458021835 2.3686869022252584 1.0799472356375237 7.80439407728393e-09 0.8458630557880957 0.08849821099172761 0.368131266588025 1.752058872430789 0.023464230602088867 0.9485326060923414 2.262900298802716e-05 4.64533458021835 -1.0799472278331297 down RPASPSS(ph)PEHLPATPAESPAQR ddPTM_PC-9_Lapatinib_30min_R1 1 RPASPSSPEHLPATPAESPAQR 22 1 Q9H7L9 Q9H7L9 SUDS3 Sin3 histone deacetylase corepressor complex component SDS3 1 RPAS(0.22)PS(0.22)S(0.56)PEHLPATPAESPAQR 58.93 0.0033520000000000004 8163300.0 18675.0 15408.0 18152.0 14477.0 20140.0 17601.0 11630.0 17332.0 16865.0 11970.0 True False 18408.691075424424 15372.32372266469 16659.612628746294 15541.686873856286 18955.404796763476 16848.24625993497 12232.144493972968 18137.307993576782 14965.486103676809 14038.998550977576 1.3112538624874046 1.094972954576897 1.1866667389595418 1.1070367175708606 1.3501963639310695 1.2001031411718308 0.8712975109696274 1.2919232043309692 1.0659938491577605 1.0 13.777152406568858 -7.058238851177481 24.999698407366644 1.0750690530644305 1.2044687277628459 0.2643532852282038 0.12194471171245046 432.9461465163834 185845.71751149293 0.04551847419561933 0.0352585259132252 8.745026881901222e-08 7.058238851177481 0.1293996746984154 RPASVSS(ph)SAAVEHEQR ddPTM_PC-9_Lapatinib_30min_R1 1 RPASVSSSAAVEHEQR 16 1 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 RPAS(0.262)VS(0.262)S(0.375)S(0.101)AAVEHEQR 77.08 0.0040062 6681200.0 10822.0 7725.2 13057.0 10837.0 17846.0 24198.0 22594.0 20800.0 21222.0 17166.0 True False 10667.676295488262 7707.312774034877 11983.503861477551 11633.98913117224 16796.333366585943 23163.10794829308 23763.80676670896 21766.443934133204 18831.75488243279 20133.120227742787 0.5298570800162684 0.3828176003943219 0.595213445602171 0.5778532586886845 0.8342637989833855 1.150497671810208 1.1803340216467393 1.0811262083529283 0.9353619642365837 1.0 14.297283157782333 -6.390610472782467 2.1075094865499655 1.081897382574712 0.498766447398571 0.9019254594289184 0.08502916513737085 0.0933535606478739 0.8167642959167799 0.03127804818379342 0.036920148696940616 4.068080396725086e-07 6.390610472782467 -0.583130935176141 RPATADS(ph)PKPSAK ddPTM_PC-9_AZD4547_30min_R2 2 RPATADSPKPSAK 13 2 Q03111 Q03111 MLLT1 Protein ENL 1 RPAT(0.048)ADS(0.626)PKPS(0.326)AK;RPAT(0.005)ADS(0.983)PKPS(0.013)AK 85.973 0.022003 39770000.0 126909.0 111522.0 112064.0 137444.0 137174.0 122634.0 120603.0 122728.0 117475.0 122993.0 True False 167263.42212881485 147569.30556842696 110577.95813868329 105758.40928863194 118129.7578955948 114965.67659365217 131336.4333610308 103763.20760887771 123684.4886700342 118687.05250615554 1.4092811186809107 1.2433479680588875 0.9316766724234584 0.8910694726633887 0.9953045037449907 0.9686454770429962 1.1065775970316494 0.8742588632698262 1.042105992678683 1.0 16.85680303533087 -5.07905051453394 3.182951553903241 0.9739438894444961 1.392721666063205 0.8245318652684958 0.06647571153364541 0.09538094978574423 1.7947914114781471 0.017401428094484306 0.06757276550229753 8.335842214548264e-06 5.07905051453394 0.41877777661870885 RPATADS(ph)PKPSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPATADSPKPSAK 13 2 Q03111 Q03111 MLLT1 Protein ENL 1 RPAT(0.003)ADS(0.99)PKPS(0.007)AK 48.948 0.036233999999999995 27172000.0 48669.0 44250.0 37720.0 51399.0 53132.0 41054.0 52136.0 47584.0 43110.0 38528.0 True False 56907.700443433554 48642.847561937895 38619.387853896624 48519.28066780633 42721.16601125333 38901.05596856349 47197.30064804721 46334.97041941551 43740.40219389273 45512.8214125198 1.2503663512229373 1.0687724041770146 0.8485386459313878 1.0660574133173712 0.9386622205649827 0.8547274100186298 1.0370110923306557 1.0180641186676587 0.9610567052619703 1.0 15.4739854035985 -4.875382903524804 3.447690676351917 0.9667287363534939 1.2599477470335958 0.6179584210951328 0.06844105839458389 0.16785134003864238 3.3777248064839998 0.017219299940782987 0.11159636817467632 1.3323462272046552e-05 4.875382903524804 0.2932190106801019 RPATADS(ph)PKPSAK ddPTM_PC-9_Lapatinib_30min_R1 2 RPATADSPKPSAK 13 2 Q03111 Q03111 MLLT1 Protein ENL 1 RPAT(0.019)ADS(0.981)PKPSAK;RPAT(0.042)ADS(0.524)PKPS(0.434)AK 79.346 0.039304 54114000.0 93837.0 84534.0 77312.0 79888.0 81936.0 81827.0 78136.0 76949.0 73456.0 73073.0 True False 92498.86717240175 84338.26671675355 70955.70579295029 85763.23001855546 77116.68557237394 78327.44995805346 82181.49975761573 80524.33145613552 65182.61175402809 85703.57068634787 1.0792883707368839 0.9840694622328985 0.8279200647617027 1.00069611256252 0.8998071486962937 0.9139344992370384 0.9589040351466571 0.9395679877893656 0.7605588802429132 1.0 16.387067692454004 -4.932465239247715 3.920911541783239 0.9142251004339613 1.074459797115315 0.35283121032120823 0.07009338525997272 0.24196178586862915 7.076724437941873 0.0169210816201155 0.08502810906522958 1.1682472321488513e-05 4.932465239247715 0.1602346966813536 RPDADLK ddPTM_PC-9_AZD4547_30min_R2 2 RPDADLK 7 1 P27824;P27824-2;P27824-3;D6RFL1;H0Y9H1;D6RGY2 P27824 CANX Calnexin 0 ; 75.738 0.020426 11791800.0 49905.0 55262.0 85776.0 82707.0 82429.0 48286.0 74749.0 71605.0 63363.0 67036.0 False True 65773.75191151546 73124.36079269036 84638.55419495724 63640.178960412166 70985.15617810951 45266.66878680535 81401.51619199956 60540.09256920752 66712.23882187164 64689.090044170305 1.016767307541419 1.1303971155377264 1.308389933096373 0.9837853479923441 1.097328098596536 0.6997573896293309 1.2583499959022124 0.9358624851249289 1.031274961145997 1.0 15.981234798623989 -5.825457543850304 24.999975278024532 1.0004317834870013 1.149711736392181 0.1820239569220079 0.1466082670933002 100.220810104206 39136.56879466266 0.040102936713915655 0.059482298964365125 1.4946601515530043e-06 5.825457543850304 0.1492799529051796 RPDADLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPDADLK 7 1 P27824;P27824-2;P27824-3;D6RFL1;H0Y9H1;D6RGY2 P27824 CANX Calnexin 0 68.383 0.031173000000000003 3013600.0 19845.0 19983.0 18764.0 17567.0 29076.0 17441.0 19424.0 17314.0 17461.0 16667.0 False True 23204.366543383654 21966.78017695381 19211.404922866277 16582.777942982422 23378.766523812425 16526.36325687424 17584.018102418067 16859.525845699387 17716.334092033423 19688.59516410059 1.1785689303873537 1.1157108972918075 0.9757631137591573 0.8422529796955147 1.1874268493488225 0.8393876312215389 0.8931067938498769 0.8563092341113491 0.8998272321804194 1.0 14.265072554166736 -3.291231451862806 0.5275671939643767 0.9081715575845776 2.466003415818169 0.4160123929107763 0.09943321932987965 17.257650690787937 1.064085595228607 0.0530311590876173 23.38408254825741 0.0005114092136979531 3.291231451862806 1.5578318582335915 RPDADLK ddPTM_PC-9_Lapatinib_30min_R1 2 RPDADLK 7 1 P27824;P27824-2;P27824-3;D6RFL1;H0Y9H1;D6RGY2 P27824 CANX Calnexin 0 ; 62.54600000000001 0.042097 9970500.0 46018.0 43622.0 18092.300000000003 13856.400000000001 17571.2 23866.0 24526.0 18130.7 31188.0 9918.599999999999 False True 45361.77488133235 43520.99593912771 16604.820932297644 14875.44587959536 16537.696562308352 22845.306814363295 25795.83627336035 18973.11851137447 27675.279015800294 11633.016794296254 3.8993990710624202 3.7411616185808603 1.427387342932325 1.2787264165980479 1.4216171827772908 1.9638333906269698 2.217467466049582 1.63097147084642 2.3790285448027264 1.0 13.505937659488545 -5.255581820524669 24.43925780315169 1.6953468142403774 3.8202808076418435 0.8197700772342715 0.4040531569698662 136.08311074459402 567767.977586828 0.10639376160327418 0.2657554138241627 5.551600158298967e-06 5.255581820524669 2.1249339934014664 RPDDVPLSLS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 1 RPDDVPLSLSPSK 13 1 F8WDB4;Q9UFC0 F8WDB4 LRWD1 Leucine-rich repeat and WD repeat-containing protein 1 1 RPDDVPLS(0.023)LS(0.939)PS(0.038)K 97.77600000000001 0.0013414000000000002 7842500.0 24946.0 29064.0 37692.0 37322.0 35770.0 41375.0 27791.0 42676.0 34854.0 25627.0 True False 32878.30909096614 38458.36962250285 37192.179452484714 28717.989519151954 30803.952935143927 38787.8147093168 30264.345161699275 36081.40479692059 36696.311284148745 24729.806530251717 1.3295012660429204 1.5551423572787406 1.5039413837301114 1.161270286689123 1.245620457946639 1.568464139089324 1.2238003206647499 1.4590249524509051 1.4838899462985498 1.0 14.593963332623915 -11.031889370887084 5.72176196872478 0.9993927750221002 1.3914479184830224 0.4214993000776005 0.13787243039409144 0.0010912709411921918 9.364288765636066e-05 0.13640709710743387 0.03303446718488108 9.292030552669598e-12 11.031889370887084 0.3920551434609222 RPDDVPLSLS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPDDVPLSLSPSK 13 1 F8WDB4;Q9UFC0 F8WDB4 LRWD1 Leucine-rich repeat and WD repeat-containing protein 1 1 RPDDVPLS(0.001)LS(0.83)PS(0.169)K;RPDDVPLS(0.001)LS(0.992)PS(0.006)K 129.42 0.00042099 8293500.0 44584.0 60123.0 47676.0 54845.0 56584.0 51224.0 55987.0 55152.0 45979.0 37422.0 True False 52131.19062586127 66091.61410093543 48812.77665223684 51772.2124598891 45496.77139164272 48537.72326530167 50683.50604922162 53704.31843837431 46651.35589127797 44206.312367611 1.1792702859344735 1.4950718700834074 1.104203767242999 1.1711497676929388 1.0291917365398071 1.097981728529435 1.1465219181312287 1.2148563307380122 1.055309827776053 1.0 15.43196477113948 -5.290029264370321 24.499639538891987 1.1113337813829194 1.3371710784302495 0.4989728098029571 0.0937596564829279 374.4112806344568 320845.1985763565 0.023025568087752277 0.047948046643442335 5.12826826656573e-06 5.290029264370321 0.22583729704733013 RPDDVPLSLS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 1 RPDDVPLSLSPSK 13 1 F8WDB4;Q9UFC0 F8WDB4 LRWD1 Leucine-rich repeat and WD repeat-containing protein 1 1 RPDDVPLSLS(0.996)PS(0.003)K 95.236 0.0016350000000000002 8596900.0 31771.0 33622.0 49865.0 39934.0 42143.0 39421.0 43725.0 38187.0 43649.0 38643.0 True False 31317.93971391218 33544.15032472954 45765.29218446641 42870.87957591879 39664.23159632588 37735.05572483933 45988.866551931846 39961.30742849733 38732.78997565307 45322.39106143912 0.691003695534455 0.7401231386767972 1.0097722364741721 0.9459094847357666 0.8751575251746311 0.8325919008484265 1.0147052146827216 0.8817122506693371 0.854606058253785 1.0 15.467936354597661 -5.13691046447991 5.549095037377175 0.9207743548921096 0.7036977774018567 0.6431094310074611 0.06314597527765443 0.13553774394130677 5.466964846195795 0.016307564604852137 0.04550487376046022 7.296079130187058e-06 5.13691046447991 -0.2170765774902529 RPDDVPLSLS(ph)PSKR ddPTM_PC-9_Lapatinib_30min_R1 2 RPDDVPLSLSPSKR 14 2 F8WDB4;Q9UFC0 F8WDB4 LRWD1 Leucine-rich repeat and WD repeat-containing protein 1 1 RPDDVPLS(0.011)LS(0.954)PS(0.035)KR;RPDDVPLS(0.012)LS(0.494)PS(0.494)KR 94.973 0.009314900000000001 124473000.0 56130.0 49028.0 45108.0 51270.0 50490.0 57407.0 39153.9 32229.3 45100.0 41721.3 True False 55329.575907018625 48914.47867827132 41399.39436191537 55040.56683170625 47520.277467159256 54951.83643225313 41181.097360495936 33726.7909368442 40020.36307594567 48932.77111486224 1.130726395550762 0.9996261720688578 0.846046390153065 1.1248201476778596 0.9711339943452749 1.123006835301889 0.8415852285134143 0.6892475158963649 0.8178642280855902 1.0 15.578513365988202 -7.384851567255547 6.126297060836537 0.8062992687540058 1.023432005416107 0.427789894035392 0.10867116400049599 0.2091283143317778 9.593128189473676 0.04498608548386917 0.030015623589354605 4.1223838945738034e-08 7.384851567255547 0.2171327366621012 RPDDVPLSLSPS(ph)KR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPDDVPLSLSPSKR 14 2 F8WDB4;Q9UFC0 F8WDB4 LRWD1 Leucine-rich repeat and WD repeat-containing protein 1 1 RPDDVPLS(0.005)LS(0.099)PS(0.895)KR;RPDDVPLSLS(0.171)PS(0.829)KR 82.774 0.0028285 65637100.0 86856.0 95650.0 76839.0 99803.0 107393.0 83720.0 102727.0 93310.0 82612.0 82888.0 True False 101559.00531580394 105145.49987117216 78671.13317353034 94211.36147569187 86350.11257710101 79329.57581936305 92995.95488092568 90860.71137011718 83820.04421345098 97914.9382589532 1.037216660926787 1.0738453369913432 0.8034640533140178 0.9621755694369476 0.881889057099061 0.8101886926544557 0.9497626872314578 0.9279555600578546 0.8560496049313149 1.0 16.579241358970364 -5.243657130593867 24.997539279331274 0.8966581149396586 1.0555310314138744 0.5112308581474333 0.06121422691343405 611.6209280392724 859788.0259049499 0.01481605297879164 0.03901781454230953 5.7061458671702984e-06 5.243657130593867 0.15887291647421575 RPDHSGGS(ph)PSPPTSEPAR ddPTM_PC-9_AZD4547_30min_R2 4 RPDHSGGSPSPPTSEPAR 18 1 Q8TAD8 Q8TAD8 SNIP1 Smad nuclear-interacting protein 1 1 RPDHS(0.008)GGS(0.967)PS(0.025)PPTSEPAR;RPDHS(0.002)GGS(0.987)PS(0.01)PPTSEPAR;RPDHS(0.208)GGS(0.743)PS(0.049)PPTSEPAR;RPDHS(0.076)GGS(0.847)PS(0.076)PPTSEPAR 107.92 0.0017261 18330200.0 19742.100000000002 21651.5 44820.9 63528.0 52573.7 37379.200000000004 28430.5 57812.4 30333.1 32733.499999999996 True False 26019.67713881033 28649.923956840772 44226.54558054422 48882.60109781593 45274.74924311925 35041.87271498479 30960.7594228236 48878.821976790096 31936.445739748997 31587.51012830199 0.8237330841564826 0.9070016547828763 1.4001276264227556 1.5475294158756048 1.4333117443958863 1.1093584955779006 0.9801582744910043 1.5474097761505843 1.011046632356577 1.0 14.947066601309091 -5.17614223383554 5.668575450213116 1.2746468722072344 0.8504172847038871 0.34631603174279113 0.21235510479409053 0.23911396914008407 12.293595521491275 0.055312097687132376 0.15248522351200156 6.665884220798734e-06 5.17614223383554 -0.42422958750334727 RPDHSGGS(ph)PSPPTSEPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RPDHSGGSPSPPTSEPAR 18 1 Q8TAD8 Q8TAD8 SNIP1 Smad nuclear-interacting protein 1 1 RPDHS(0.028)GGS(0.949)PS(0.023)PPTSEPAR;RPDHS(0.311)GGS(0.664)PS(0.025)PPTSEPAR;RPDHS(0.001)GGS(0.996)PS(0.004)PPTSEPAR 155.53 7.192000000000001e-06 45148200.0 16969.1 18494.5 37612.3 27719.100000000002 29658.8 25475.2 24574.7 24869.600000000002 24987.9 16941.399999999998 True False 19841.633474997798 20330.5117341076 38509.11987744206 26166.088693534697 23847.371047477227 24139.235665473483 22246.806510579358 24216.799351519334 25353.30076503762 20012.74171195139 0.9914500352117468 1.015878385217276 1.9242300945924287 1.3074714634381455 1.1916093951902573 1.206193334872143 1.1116321207150648 1.2100690500121394 1.2668579413033103 1.0 14.288631207126844 -6.256036625850933 5.462913884679863 1.1736494177762447 1.3335764426345083 0.07317681283756572 0.24748783545344413 0.5004949067623877 54.78287748790092 0.07973345208825446 0.09781051907763925 5.545789410485493e-07 6.256036625850933 0.1599270248582636 RPDHSGGS(ph)PSPPTSEPAR ddPTM_PC-9_Lapatinib_30min_R1 4 RPDHSGGSPSPPTSEPAR 18 1 Q8TAD8 Q8TAD8 SNIP1 Smad nuclear-interacting protein 1 1 RPDHS(0.002)GGS(0.997)PS(0.001)PPTSEPAR;RPDHS(0.127)GGS(0.866)PS(0.007)PPTSEPAR;RPDHS(0.175)GGS(0.807)PS(0.018)PPTSEPAR;RPDHS(0.001)GGS(0.998)PSPPTSEPAR 123.61 2.0855e-05 47793000.0 44440.9 31279.5 49130.7 35370.5 41833.9 45549.8 35845.3 38097.8 48289.6 33018.9 True False 43807.16461653708 31207.07423955677 45091.36349598646 37971.76456252905 39373.312250611896 43601.7412357699 37701.19424160006 39867.96287085674 42850.71673596866 38726.17287008134 1.1312030435721458 0.8058393568672623 1.164364050309311 0.9805194200293642 1.0167106463812363 1.125898533326418 0.9735326640223427 1.029483677734071 1.106505331154833 1.0 15.241021313031075 -5.284333752896047 24.999657824887223 1.0470424109008476 0.9685210627185854 0.10451557855764892 0.09472042283379326 1538.67407234532 1680162.8541187127 0.022941659000540317 0.04781246894607793 5.195965360109589e-06 5.284333752896047 -0.0785213481822622 RPDQQLQGEGK ddPTM_PC-9_Lapatinib_30min_R1 2 RPDQQLQGEGK 11 1 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 ; 128.08 0.00020748 18114400.0 98939.0 102871.0 95594.0 84395.0 88389.0 85004.0 77027.0 81402.0 104414.0 76441.0 False True 97528.11171680948 102632.80851987559 87734.63032351097 90601.68983346692 83190.13279946004 81368.57707400221 81015.08116399443 85184.23409261124 92653.79579183584 89653.7249987702 1.0878311159759095 1.144769037999073 0.9785943676597313 1.0105736246286445 0.9279049230871466 0.9075872427511336 0.9036443400997085 0.9501471812105937 1.0334628683092286 1.0 16.45207590604086 -5.351161849998893 4.092014231950673 0.9561867703275563 1.1165147663778527 0.6624349245220402 0.04330788529869922 0.12844969870199505 3.8564830485118384 0.012286145561600105 0.02796908720717994 4.454901951142629e-06 5.351161849998893 0.16032799605029646 RPEAS(ph)PVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPEASPVQK 9 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 RPEAS(1)PVQK 60.301 0.032363 4708400.0 19961.0 28676.0 18945.0 20562.0 16870.0 16071.0 21512.0 18720.0 16105.0 13520.0 True False 23340.003052279226 31522.76376691822 19396.7206493126 19409.977802903435 13564.444602308291 15228.208468621415 19474.227626607168 18228.619835479527 16340.505157333391 15971.068975738892 1.4613926649327125 1.9737416333749092 1.2144910699952207 1.2153211430235804 0.8493135069990354 0.9534871142159657 1.2193440311471828 1.1413525208093462 1.023131587632343 1.0 13.963173258008345 -5.426218742376365 4.430597777964988 1.0656469856051594 1.713513754549976 0.7267165475531026 0.15908104374111584 0.10871932426130539 3.5940324213075496 0.042310536716157796 0.0915105103103938 3.7478418604768344e-06 5.426218742376365 0.6478667689448165 RPEGPGAQAPS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 RPEGPGAQAPSSPR 14 1 P40222 P40222 TXLNA Alpha-taxilin 1 RPEGPGAQAPS(0.753)S(0.247)PR 82.57799999999999 0.013336 1544000.0 6622.9 3856.6 5524.9 7928.1 8691.8 6510.2 5224.8 5933.6 5716.5 5411.1 True False 8728.84443512225 5103.170530076537 5451.636216094472 6100.399032923974 7485.093601388984 6103.116164848198 5689.797078221236 5016.698460563508 6018.6625195339475 5221.659036010659 1.6716611281825624 0.9773082644582923 1.0440429331937986 1.1682875099375831 1.433470387432188 1.1688078679129863 1.0896531234579103 0.960747997133926 1.1526341490370842 1.0 12.350292540260664 -4.752216179519316 24.99648772085028 1.120308327763394 1.6716622024318069 0.623061604029377 0.13073197982924364 268.54242310770894 727744.7620474155 0.03529505854067771 0.4302493310835832 1.7692280673632508e-05 4.752216179519316 0.5513538746684128 RPEGPGAQAPS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RPEGPGAQAPSSPR 14 1 P40222 P40222 TXLNA Alpha-taxilin 1 RPEGPGAQAPS(0.5)S(0.5)PR;RPEGPGAQAPS(0.606)S(0.394)PR;RPEGPGAQAPS(0.757)S(0.243)PR 91.14 0.0021343000000000004 328647400.0 45987.9 56648.0 60268.3 64004.8 73842.8 71946.8 63474.4 68043.5 66784.2 59795.1 True False 53772.74316757236 62271.63906641037 61705.32484080057 60418.818562361346 59373.83342497514 68173.78315289722 57461.645317139904 66257.4302230476 67760.79258170647 70635.47829224872 0.7612710279258232 0.8815915255612253 0.8735741065629888 0.8553607906834473 0.8405667358734458 0.965149310249356 0.8134955224539838 0.9380191346466532 0.9593025236036703 1.0 16.108105371825992 -1.522878750186109 0.059162008543666975 1.1907589553159392 0.2617310925922688 0.5550241114988915 0.04775487386486789 275.406681888342 1.2231234709532393 3.946952452047596 22.15342749666623 0.02999999966112132 1.522878750186109 -0.9290278627236704 RPEGPGAQAPS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 RPEGPGAQAPSSPR 14 1 P40222 P40222 TXLNA Alpha-taxilin 1 RPEGPGAQAPS(0.674)S(0.326)PR 127.32 4.2821e-05 98316000.0 8149.2 8965.3 9662.7 10601.0 10979.0 10157.0 13326.0 13858.0 11604.0 9758.0 True False 8032.990913619749 8944.541398676392 8868.270105100646 11380.632903899314 10333.236805544497 9722.60878712343 14015.95507538123 14501.893271116247 10297.035324462831 11444.657298282298 0.7018987728732954 0.781547333882934 0.7748829758695932 0.994405739489238 0.9028873941988099 0.8495325402694822 1.2246723261416357 1.2671321554812132 0.8997242168193441 1.0 13.48238664266402 -6.105648660747059 0.6859849182796683 1.09863131201496 0.7006331509286531 0.503672703692355 0.1250093620207189 0.7439161895400255 0.7104623106372498 0.07859223426090609 0.17816720983842138 7.840636847902369e-07 6.105648660747059 -0.3979981610863069 RPEGPGAQAPSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 9 RPEGPGAQAPSSPR 14 1 P40222 P40222 TXLNA Alpha-taxilin 1 RPEGPGAQAPS(0.005)S(0.995)PR;RPEGPGAQAPS(0.02)S(0.98)PR;RPEGPGAQAPS(0.387)S(0.613)PR;RPEGPGAQAPS(0.05)S(0.95)PR;RPEGPGAQAPS(0.183)S(0.817)PR;RPEGPGAQAPS(0.126)S(0.874)PR;RPEGPGAQAPS(0.003)S(0.997)PR;RPEGPGAQAPS(0.118)S(0.882)PR;RPEGPGAQAPS(0.009)S(0.991)PR 129.05 1.0897000000000001e-05 2015601800.0 327676.9 308765.39999999997 403805.5 477458.1 436464.6 417164.5 345096.3 471274.3 343490.8 374098.3 True False 431871.3380970728 408567.77731351287 398450.77522817336 367387.5116991106 375869.0242174 391079.1378683936 375809.2021598832 398449.68574105896 361647.0224376336 361001.23238365975 1.1963154121260582 1.1317628325415272 1.1037379916883872 1.0176904640277342 1.0411848783328785 1.083318013310182 1.0410191668279019 1.1037349737288438 1.0017888860093627 1.0 18.461644236620614 -5.1397726248389395 1.497696679381404 1.047619333773542 1.2043002919960069 0.6939140135917421 0.03325992181435683 0.3517614966248944 1.1520883307294119 0.009496852651614705 0.06704430075255272 7.248153383005827e-06 5.1397726248389395 0.15668095822246486 RPEGPGAQAPSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RPEGPGAQAPSSPR 14 1 P40222 P40222 TXLNA Alpha-taxilin 1 RPEGPGAQAPS(0.003)S(0.997)PR;RPEGPGAQAPS(0.129)S(0.871)PR;RPEGPGAQAPS(0.019)S(0.981)PR;RPEGPGAQAPS(0.078)S(0.922)PR 139.49 4.747e-05 1157249100.0 112994.8 138609.0 140063.0 140648.0 188248.0 173474.0 201422.0 170956.0 160600.0 137478.0 True False 132122.58789097128 152369.1854850314 143402.63311188528 132767.94854696823 151362.15574957468 164376.7180564765 182341.8499910032 166468.58614285442 162948.47117465042 162401.67312475046 0.81355435168134 0.9382242347219384 0.8830120426267353 0.8175282064057382 0.9320233765898726 1.0121614814288822 1.122783075337749 1.0250423098472632 1.0033669483779266 1.0 17.309206970237895 -6.675133897414338 2.948582267999893 1.0422867324898368 0.8701877742818681 0.7479301712021094 0.0464472609571179 0.13010746845898502 2.284401033702049 0.0168002202375964 0.016402035442073477 2.1128375300674043e-07 6.675133897414338 -0.17209895820796872 RPEGPGAQAPSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 6 RPEGPGAQAPSSPR 14 1 P40222 P40222 TXLNA Alpha-taxilin 1 RPEGPGAQAPS(0.148)S(0.852)PR;RPEGPGAQAPS(0.04)S(0.96)PR;RPEGPGAQAPS(0.233)S(0.767)PR;RPEGPGAQAPS(0.018)S(0.982)PR;RPEGPGAQAPS(0.255)S(0.745)PR;RPEGPGAQAPS(0.048)S(0.952)PR 105.5 0.00044248 762429600.0 140089.1 165917.4 189212.2 161077.9 200674.6 195763.0 198187.0 209289.9 234710.8 162953.1 True False 138091.40374480558 165533.22845423463 173655.90329621406 172924.1061061221 188871.3145694435 187390.6728358418 208448.1531235613 219014.27280434326 208275.19808970456 191119.32621364266 0.7225402395487736 0.8661250106605827 0.9086255520914347 0.9047965453416206 0.9882376539896011 0.9804904430563303 1.0906701967468617 1.1459556557850055 1.0897652383772232 1.0 17.544114147167733 -5.495256406674478 0.49937287895580174 1.0966802565919798 0.6634317808075866 0.8260358327391604 0.04957093548598094 0.9566184659014845 0.30434739103274855 0.03699387332064645 0.2255963865519456 3.197007045229925e-06 5.495256406674478 -0.4332484757843932 RPEPSTLENITDDKYATVS(ph)SPSK ddPTM_PC-9_Lapatinib_30min_R1 1 RPEPSTLENITDDKYATVSSPSK 23 2 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 RPEPSTLENITDDKYAT(0.009)VS(0.429)S(0.429)PS(0.132)K 88.176 8.3512e-06 23307000.0 50960.0 64866.0 43638.0 50217.0 70131.0 69281.0 52739.0 46641.0 56079.0 58905.0 True False 50233.30105508057 64715.80676235513 40050.252087551286 53910.12569900123 66006.03246285093 66318.01313189903 55469.56736609116 48808.11113134169 49762.79248195031 69086.6507640211 0.7271057505257011 0.9367338848630042 0.5797104309535964 0.7803262294931875 0.9554093552502259 0.9599251432584437 0.8028984869386455 0.7064767301870702 0.720295338269108 1.0 16.076119353012906 -6.015243065491387 24.79328367183677 0.8472750546201386 0.7522850767686017 0.14204883806469737 0.12250005890930865 1498.531421357332 2437408.044352332 0.037559063958929634 0.05020278817508409 9.655103518969785e-07 6.015243065491387 -0.09498997785153696 RPEPSTLENITDDKYATVSS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 1 RPEPSTLENITDDKYATVSSPSK 23 2 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 RPEPSTLENITDDKYAT(0.002)VS(0.047)S(0.648)PS(0.303)K 89.079 7.5751e-06 44990000.0 82466.0 98510.0 70080.0 61255.0 92183.0 97228.0 93379.0 99824.0 116260.0 90350.0 True False 108688.47260064205 130351.4310319556 69150.69341054143 47133.606130315995 79384.98164440517 91148.3177899082 101689.55010090722 84398.49452731744 122405.266250506 87186.8740003995 1.2466150879562905 1.4950809112775199 0.7931319272924565 0.5406043819176269 0.9105152874736788 1.0454362406603834 1.1663401316629527 0.9680183570629073 1.4039414493739633 1.0 16.411823332901086 -9.455236419379649 15.048817077384985 1.0000016244203003 1.047887604746496 0.002013898739280151 0.26977264320564864 0.0 0.0 0.282602530451687 0.06854118135994924 3.5056098510422654e-10 9.455236419379649 0.04788598032619573 RPEPSTLENITDDKYATVSS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RPEPSTLENITDDKYATVSSPSK 23 2 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 RPEPSTLENIT(0.006)DDKY(0.016)AT(0.073)VS(0.418)S(0.432)PS(0.055)K;RPEPSTLENIT(0.001)DDKY(0.094)AT(0.079)VS(0.383)S(0.403)PS(0.041)K;RPEPSTLENITDDKY(0.001)AT(0.017)VS(0.208)S(0.711)PS(0.063)K 70.76100000000001 0.00030424 53145000.0 113929.0 124015.0 125946.0 138049.0 146102.0 116166.0 150139.0 139331.0 116938.0 102976.0 True False 133214.92949968032 136326.38961341776 128949.03029286508 130314.56209089672 117474.3619019828 110074.05046144464 135916.74700777116 135673.70888339754 118647.99702503881 121644.7336424328 1.0951146466501165 1.1206929024493637 1.060046139538624 1.0712717122136035 0.965716791713248 0.9048813472270861 1.1173253698535777 1.1153274360582026 0.9753648470619147 1.0 16.892314337562247 -5.7467725127812095 2.0878511244321185 1.0200410265223014 1.103744460741586 0.24355760664335813 0.06275901631971988 0.528105199069721 4.693633483635237 0.020767443686570537 0.040889362577557604 1.791544034614122e-06 5.7467725127812095 0.08370343421928461 RPES(ph)PPSILTPPVVPTADK ddPTM_PC-9_AZD4547_30min_R2 2 RPESPPSILTPPVVPTADK 19 1 P55198;Q6P2C6 P55198 MLLT6 Protein AF-17 1 RPES(0.71)PPS(0.279)ILT(0.011)PPVVPTADK;RPES(0.586)PPS(0.083)ILT(0.33)PPVVPTADK 68.406 0.0038830999999999996 7013700.0 57381.0 63249.0 75639.0 72931.0 71260.0 79363.0 67504.0 89096.0 73295.0 68119.0 True False 75626.96440105533 83693.0023483926 74635.97743835542 56117.884722717754 61366.779037136046 74400.41906406058 73511.72522742441 75328.26042240212 77169.22406529191 65734.17454380986 1.150496905542675 1.2732038232656855 1.1354212318983754 0.8537094306298296 0.9335597421435167 1.1318377325096693 1.118318222410035 1.1459527855209939 1.1739589734082831 1.0 16.0043559879429 -5.524519357030678 24.99995982182583 1.0534926863057514 1.209965936030663 0.3013055286006072 0.0990432312035805 66.98343485731515 1020703.7130095917 0.029852151558231815 0.05218287958313328 2.988688434529992e-06 5.524519357030678 0.1564732497249115 RPES(ph)PPSILTPPVVPTADK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RPESPPSILTPPVVPTADK 19 1 P55198;Q6P2C6 P55198 MLLT6 Protein AF-17 1 RPES(0.805)PPS(0.09)ILT(0.104)PPVVPTADK;RPES(0.941)PPS(0.045)ILT(0.014)PPVVPTADK;RPES(0.952)PPS(0.038)ILT(0.011)PPVVPTADK 97.25299999999999 0.00028195 15850500.0 101376.0 123570.0 106880.0 109384.0 128280.0 86939.0 119768.0 85297.0 92435.0 88541.0 True False 118536.9545327315 135837.2129543199 109428.42454465739 103255.56910771278 103144.45486568497 82379.76579263747 108422.7079947698 83058.04412964202 93786.68700516081 104592.78240982941 1.133318684154172 1.2987245374357133 1.0462330384890262 0.9872150518295136 0.986152700876917 0.7876238101195747 1.0366174940249075 0.7941087541221812 0.8966841195377449 1.0 16.674423774006243 -5.654674606526707 1.516060568136707 0.9061005222208113 1.2224401899591002 0.6247183606499643 0.08854207456914517 0.24744422648976241 1.123038906405253 0.02695115706463668 0.0706207473888941 2.2147534836581013e-06 5.654674606526707 0.3163396677382889 RPES(ph)PPSILTPPVVPTADK ddPTM_PC-9_Lapatinib_30min_R1 2 RPESPPSILTPPVVPTADK 19 1 P55198;Q6P2C6 P55198 MLLT6 Protein AF-17 1 RPES(0.744)PPS(0.246)ILT(0.01)PPVVPTADK;RPES(0.955)PPS(0.045)ILTPPVVPTADK 110.6 6.5343e-05 7926400.0 67949.0 114041.0 120000.0 104534.0 129851.0 125886.0 134733.0 132942.0 114638.0 107748.0 True False 66980.03479967943 113776.94507115836 110134.06321339536 112221.7790752013 122213.41947688839 120502.1492345988 141708.81548636794 139118.97064863134 101726.26124834291 126372.09823481453 0.5300223366966851 0.9003328002020441 0.8715061690971772 0.8880265552501926 0.9670917962428793 0.9535502766654339 1.121361577957311 1.1008677753386003 0.8049740620696453 1.0 16.947318439678405 -4.339816072012511 0.9076468934106057 0.9903935117260051 1.6048975421749533e-33 0.6510664137124416 0.09371387947439899 2.8434112242623333 1.0608189047620533 0.03263802797412886 3.371228659374385 4.5728181195950944e-05 4.339816072012511 -0.9903935117260051 RPES(ph)PSEISPIK ddPTM_PC-9_AZD4547_30min_R2 2 RPESPSEISPIK 12 1 Q7Z5K2;Q7Z5K2-2;Q7Z5K2-3 Q7Z5K2 WAPAL Wings apart-like protein homolog 1 RPES(0.953)PS(0.031)EIS(0.017)PIK;RPES(0.993)PS(0.007)EISPIK 92.95200000000001 0.0025587 39995000.0 56046.0 66069.0 68211.0 98344.0 89213.0 89905.0 61409.0 81589.0 66765.0 71038.0 True False 73867.4621707804 87424.51220028699 67306.4775717243 75672.3101996539 76827.31487847354 84283.22613754979 66874.28203500378 68981.29477870357 70294.0615965511 68550.98124228431 1.0775551397244876 1.2753210911933806 0.9818455746656423 1.103883691061988 1.1207325334547382 1.2294970051509833 0.9755408430791901 1.006277277562204 1.0254275040660046 1.0 16.064889696513042 -7.284268254837474 24.979735676493043 1.0023345003732593 1.1294676429246828 0.4110754367998982 0.07600612948210268 838.6916816733353 917706.1899935501 0.031645982220770516 0.02135154253339107 5.1967490479574764e-08 7.284268254837474 0.1271331425514235 RPES(ph)PSEISPIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RPESPSEISPIK 12 1 Q7Z5K2;Q7Z5K2-2;Q7Z5K2-3 Q7Z5K2 WAPAL Wings apart-like protein homolog 1 RPES(0.95)PS(0.031)EIS(0.02)PIK;RPES(0.952)PS(0.018)EIS(0.03)PIK;RPES(0.976)PS(0.016)EIS(0.008)PIK 85.837 0.0084837 21644300.0 61683.0 59021.0 50186.0 66168.0 73863.0 55751.0 59647.0 44914.0 44351.0 44422.0 True False 72124.71360521716 64880.21482379973 51382.62457146489 62460.82147955032 59390.075379981994 52827.31941597361 53996.80435311628 43735.055090316666 44999.54947115139 52475.35695564151 1.3744492232074885 1.2363939682896163 0.9791762753495831 1.1902886441029783 1.1317707744262824 1.006707195162667 1.0289935597534072 0.833439877832309 0.8575367959705434 1.0 15.67935245481404 -1.522878745280339 0.2728737136188198 0.8963841732259302 4.249014272972569 0.677997508578252 0.09118593933795252 31.92752973738736 0.4471754317153239 0.11225536691319771 50.59030849294514 0.029999999999999905 1.522878745280339 3.3526300997466385 RPES(ph)PSEISPIK ddPTM_PC-9_Lapatinib_30min_R1 3 RPESPSEISPIK 12 1 Q7Z5K2;Q7Z5K2-2;Q7Z5K2-3 Q7Z5K2 WAPAL Wings apart-like protein homolog 1 RPES(0.891)PS(0.109)EISPIK;RPES(0.993)PS(0.007)EISPIK;RPES(0.98)PS(0.019)EIS(0.001)PIK 118.19 0.00027328 30695900.0 109533.0 118087.0 125923.0 95741.0 123543.0 128369.0 114862.0 107113.0 117023.0 85085.0 True False 107971.03933410777 117813.57680674357 115570.09701683656 102782.1125226135 116276.44363488317 122878.95711275456 120808.99233591773 112089.86101523157 103842.63743317929 99791.82888136398 1.0819627272536263 1.180593422601809 1.158111824508501 1.029965215336463 1.165190025459065 1.231352892217632 1.2106100638714588 1.123236864898908 1.0405925875617636 1.0 16.60663406971169 -10.392905487795735 6.067431290711725 0.999999981443553 1.1401149170594944 0.2829216476524078 0.06448975861876836 1.799975008418067e-08 3.2284585546156e-09 0.06572792382756548 0.01594136094995691 4.04663946051953e-11 10.392905487795735 0.14011493561594146 RPESPPS(ph)ILTPPVVPTADK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPESPPSILTPPVVPTADK 19 1 P55198;Q6P2C6 P55198 MLLT6 Protein AF-17 1 RPES(0.258)PPS(0.722)ILT(0.02)PPVVPTADK 106.74 9.8865e-05 6480700.0 29392.0 44155.0 37534.0 35652.0 41258.0 29054.0 38583.0 29688.0 27972.0 21705.0 True False 34367.48508153856 48538.41658977104 38428.952908487656 33654.53402534353 33173.79107303115 27530.357093356128 34928.138923269995 28908.721457036143 28381.037582175075 25639.94468331453 1.3403884254049725 1.8930780541565653 1.4987923485457326 1.3125821619749662 1.2938323963943397 1.073729192219038 1.3622548470629057 1.1274876687175073 1.1069071299769355 1.0 14.64610552897904 -5.886830527181311 1.7250420442300973 1.1671780658756628 1.6309030469045998 0.5844134567251996 0.15859145724239876 0.2422660988904523 1.468273628119473 0.04937203929344141 0.09130599542880681 1.297685562302587e-06 5.886830527181311 0.463724981028937 RPFDPNDR ddPTM_PC-9_AZD4547_30min_R2 1 RPFDPNDR 8 1 Q16629-4;Q16629;A0A0B4J1Z1;C9JAB2;Q16629-3;Q16629-2;F8WEA1 Q16629-4 SRSF7 Serine/arginine-rich splicing factor 7 0 83.647 0.009338899999999999 7718500.0 5086.4 4048.8 5103.4 6939.6 5754.3 5657.7 3551.9 8333.3 4295.4 4982.2 False True 6703.7693963076235 5357.495421400683 5035.725581497674 5339.7824357512145 4955.414771448101 5303.923124613937 3868.012219057952 7045.579965183675 4522.446074767102 4807.774694463658 1.3943601400513377 1.114339951822212 1.0474129720131249 1.1106557139418751 1.0307086097762561 1.1031971050393883 0.8045327547299835 1.4654555200552426 0.9406526641056779 1.0 12.231153573640439 -4.761891356020556 3.7234527556293275 1.0724383981431178 1.435796708366968 0.27689640905200796 0.15926433322297331 0.37269793488738195 8.85820478877364 0.03783646733454672 0.38704083492715396 1.7302491476795088e-05 4.761891356020556 0.36335831022385023 RPFDPNDR ddPTM_PC-9_Lapatinib_30min_R1 2 RPFDPNDR 8 1 Q16629-4;Q16629;A0A0B4J1Z1;C9JAB2;Q16629-3;Q16629-2;F8WEA1 Q16629-4 SRSF7 Serine/arginine-rich splicing factor 7 0 ; 99.01299999999999 0.0033726 15079300.0 15448.5 11332.5 13589.8 11291.6 10814.3 12424.1 13611.7 10485.2 12849.0 10215.900000000001 False True 15228.201557092076 11306.260292516727 12472.499102145031 12122.021931673378 10178.224135731836 11892.750204991658 14316.447223440387 10972.380670104494 11401.810314031618 11981.704703168913 1.2709545039166699 0.9436270190773818 1.040961984219684 1.0117109569949052 0.849480469422678 0.9925758061660686 1.194858960232427 0.9157612328070919 0.9516016791013114 1.0 13.5485455624546 -4.755525680474425 24.998927945999007 0.9908463610004778 1.270954958176228 0.49139094130396277 0.08605042204127604 175.18383658013244 740479.5831721767 0.02201936033777586 0.19360019675529475 1.755797068254487e-05 4.755525680474425 0.2801085971757502 RPGAPSLS(ph)PAPR ddPTM_PC-9_AZD4547_30min_R2 3 RPGAPSLSPAPR 12 1 Q5QP82;Q5QP82-2 Q5QP82;Q5QP82-2 DCAF10 DDB1- and CUL4-associated factor 10 1 RPGAPS(0.202)LS(0.798)PAPR;RPGAPS(0.004)LS(0.996)PAPR;RPGAPS(0.018)LS(0.982)PAPR 73.296 0.010542000000000001 29081200.0 91132.0 94429.0 103569.0 124282.0 121042.0 109354.0 106579.0 113199.0 97976.0 110009.0 True False 120110.08033664423 124951.32759026012 102195.60738921768 95630.70503775911 104237.40763700545 102516.07709299418 116064.32452911869 95706.69560424164 103154.81133803165 106157.61839413385 1.1314315651911928 1.1770358970031753 0.962678034183036 0.9008369487219351 0.9819117008635293 0.9656968444071565 1.0933207270928402 0.9015527764470862 0.9717136923234881 1.0 16.695848384305087 -5.2642666145045265 24.967885039520556 0.970587537432437 1.1542337409508032 0.6639857287875734 0.051783526663710305 129.09145221611232 1140045.1508146203 0.013640838392766568 0.03055149882308272 5.441684838411121e-06 5.2642666145045265 0.18364620351836625 RPGAPSLS(ph)PAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPGAPSLSPAPR 12 1 Q5QP82;Q5QP82-2 Q5QP82;Q5QP82-2 DCAF10 DDB1- and CUL4-associated factor 10 1 RPGAPS(0.004)LS(0.996)PAPR;RPGAPS(0.01)LS(0.99)PAPR 81.44800000000001 0.0060479 6759900.0 35826.0 42090.0 38147.0 43991.0 47986.0 46892.0 43685.0 41815.0 37790.0 38851.0 True False 41890.634204246046 46268.41703688064 39056.569153303135 41526.326890746284 38583.48777038325 44432.90097135181 39546.84054798878 40717.40055665474 38342.607258343916 45894.37875565323 0.9127617660384169 1.0081499802670568 0.851009866834556 0.9048238153922304 0.8407018204954037 0.9681556255051954 0.8616924691047797 0.8871979893973225 0.8354532362772402 1.0 15.4860298395508 -5.265917359953598 24.984390397264562 0.8896312929780783 0.960455872535913 0.18587871598354055 0.05543921252609411 500.6008291576616 2793062.4128580876 0.01337549881917187 0.029461510261708207 5.421040352547399e-06 5.265917359953598 0.07082457955783472 RPGAPSLS(ph)PAPR ddPTM_PC-9_Lapatinib_30min_R1 2 RPGAPSLSPAPR 12 1 Q5QP82;Q5QP82-2 Q5QP82;Q5QP82-2 DCAF10 DDB1- and CUL4-associated factor 10 1 RPGAPS(0.007)LS(0.993)PAPR;RPGAPS(0.017)LS(0.983)PAPR 76.574 0.0084837 14499700.0 73168.0 63739.0 56447.0 43884.0 48746.0 56449.0 52547.0 43778.0 55084.0 36798.0 True False 72124.61090263215 63591.41626161248 51806.14555172113 47111.37575273254 45878.856118323354 54034.80785904605 55267.626545554325 45812.085699446354 48879.85985976481 43158.485269747114 1.6711571421434819 1.473439483896537 1.2003698746127167 1.0915901116148832 1.063032120603249 1.2520089044210023 1.2805738245937788 1.0614850223105337 1.1325666217027366 1.0 15.397356611099841 -5.105448040702094 2.06918270916004 1.1364358707653883 1.6851788265369987 0.8305235867193052 0.0818275424315726 0.1634645416942872 1.1764206036206046 0.023729158698237097 0.1304709481445973 7.844259625431117e-06 5.105448040702094 0.5487429557716104 RPGFS(ph)PTSHR ddPTM_PC-9_AZD4547_30min_R2 1 RPGFSPTSHR 10 1 Q8WUA4;H0Y4Q6 Q8WUA4 GTF3C2 General transcription factor 3C polypeptide 2 1 RPGFS(0.975)PT(0.023)S(0.002)HR 64.53399999999999 0.023456 29961000.0 11564.0 10697.0 18929.0 17592.0 12948.0 19905.0 20137.0 15281.0 18662.0 15652.0 True False 15241.111453857628 14154.596058763858 18677.98909201111 13536.436193690624 11150.39369874876 18660.33720335834 21929.153989461993 12919.672572446902 19648.435220771888 15104.028244098019 1.0090759370642182 0.9371404654446964 1.236623024676191 0.8962136441303372 0.7382397277432156 1.2354543371997446 1.4518745353929623 0.8553792646339452 1.3008738399605164 1.0 13.88264574716256 -6.80751852632006 24.999719045898303 1.1773751424685988 0.9734350246042578 0.2238101941575188 0.1903297557571572 203.67938900995543 110502.47344315401 0.0674791269142432 0.05951119346036001 1.5576915847393488e-07 6.80751852632006 -0.20394011786434096 RPGFS(ph)PTSHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPGFSPTSHR 10 1 Q8WUA4;H0Y4Q6 Q8WUA4 GTF3C2 General transcription factor 3C polypeptide 2 1 RPGFS(0.993)PT(0.003)S(0.003)HR 55.31399999999999 0.041489 13468000.0 12092.0 13120.0 12893.0 13427.0 17287.0 12577.0 13044.0 11389.0 16242.0 12968.0 True False 14138.93677211364 14422.466892940685 13200.418016974781 12674.728720921335 13899.736445767836 11917.439979456882 11808.377889618063 11090.050817642965 16479.508523154847 15318.995745368473 0.9229676022586787 0.9414760035625153 0.8617025708728838 0.8273863986647687 0.9073529803655873 0.7779517781418528 0.7708323760836734 0.7239411121969871 1.075756452777738 1.0 13.903034102356338 RPGFS(ph)PTSHR ddPTM_PC-9_Lapatinib_30min_R1 4 RPGFSPTSHR 10 1 Q8WUA4;H0Y4Q6 Q8WUA4 GTF3C2 General transcription factor 3C polypeptide 2 1 RPGFS(0.992)PT(0.004)S(0.004)HR;RPGFS(0.863)PT(0.068)S(0.068)HR;RPGFS(0.925)PT(0.056)S(0.019)HR;RPGFS(0.729)PT(0.135)S(0.135)HR 69.229 0.017845 71350700.0 49293.9 53964.4 58312.9 47094.7 60089.3 47716.1 51043.6 54334.7 58599.7 49456.1 True False 48590.95994660588 53839.44874736285 53518.63845630344 50558.20134131378 56554.96551410917 45675.393634661836 53686.387849747065 56859.2885205744 51999.584703802495 58004.52098888906 0.8377098736133624 0.9281940067684716 0.9226632259674223 0.8716251850609775 0.9750096121807892 0.7874454069435569 0.925555231462576 0.9802561516104231 0.8964746853743206 1.0 15.823877730721707 -8.712750576170677 0.6084988869909095 0.999620422008133 0.8936523221266716 0.24045798000892415 0.05500536724006867 1.6159429439818678 1.2954569099349693 0.059071096865231446 0.02353894576263039 1.9375344084361564e-09 8.712750576170677 -0.10596809988146139 RPGHPAQPLPLPQTAS(ph)SPQPQQK ddPTM_PC-9_AZD4547_30min_R2 1 RPGHPAQPLPLPQTASSPQPQQK 23 1 O60346 O60346 PHLPP1 PH domain leucine-rich repeat-containing protein phosphatase 1 1 RPGHPAQPLPLPQT(0.018)AS(0.491)S(0.491)PQPQQK 64.83 0.00068678 11496000.0 11501.0 16102.0 17067.0 26478.0 23882.0 20941.0 21225.0 31186.0 25381.0 22723.0 True False 15158.078764339034 21306.65660822807 16840.680428620293 20373.906181022074 20566.39653332701 19631.555959584362 23113.98388172671 26366.92028298729 26722.58784366153 21927.474686342925 0.6912824655444674 0.9716876618491085 0.7680173239059381 0.9291496842411836 0.9379281849604125 0.8952948864563721 1.0541106174949904 1.2024604137114512 1.2186805925401498 1.0 14.420452050782453 -7.354083686455022 2.1766122706454345 1.1586774644302131 0.8659004847528742 0.6322537411480351 0.09598273972551168 0.19565053368396593 1.8097593736077058 0.04773453263996741 0.028738693908749082 4.4250309593130075e-08 7.354083686455022 -0.29277697967733896 RPGNSTVTS(ph)SPPVTPK ddPTM_PC-9_AZD4547_30min_R2 1 RPGNSTVTSSPPVTPK 16 1 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 RPGNS(0.001)T(0.001)VT(0.1)S(0.516)S(0.38)PPVT(0.001)PK 58.693000000000005 0.024068 6951000.0 24443.0 30748.0 33840.0 49860.0 35233.0 36660.0 23524.0 34124.0 28474.0 29646.0 True False 32215.365554016054 40686.689690087995 33391.25948933678 38365.54732932094 30341.506115849203 34367.644404678045 25617.590427973562 28850.919891510912 29979.077509176892 28608.102563540113 1.1260923538170355 1.4222086068001434 1.167195881487527 1.3410727693005515 1.0605913498967332 1.201325545039056 0.8954662536977255 1.0084877117394098 1.047922610127385 1.0 14.804136193430432 -6.716133284135399 1.3060254627234194 0.994646545360195 1.2683881596617312 0.5374721956032478 0.10415910737013338 0.30920997631157615 1.1072819095723287 0.04609174032491165 0.04333445004831248 1.9225016263383036e-07 6.716133284135399 0.2737416143015362 RPGNSTVTSS(ph)PPVTPK ddPTM_PC-9_AZD4547_30min_R2 1 RPGNSTVTSSPPVTPK 16 1 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 RPGNS(0.002)T(0.002)VT(0.005)S(0.156)S(0.623)PPVT(0.213)PK 49.595 0.04554 4661800.0 21457.0 25815.0 29626.0 40377.0 31410.0 34052.0 23867.0 31131.0 27017.0 30001.0 True False 28279.879666674413 34159.193910160706 29233.139882715477 31068.70646843144 27049.2636760657 31922.72305695843 25991.116763494505 26320.41926921302 28445.06346370134 28950.674121593707 0.9768297466199946 1.1799101384199573 1.0097567939155891 1.0731600355121933 0.9343224120605266 1.1026590580544697 0.8977724198867021 0.9091470256846684 0.9825354443986766 1.0 14.821309321565588 -6.5449834979018275 0.904736979969705 0.9496789314056062 1.0722957278751206 0.23428756280228225 0.07413561193288934 0.7391618368558138 1.3244877064027605 0.040002060956429226 0.04680498433188063 2.851126601086679e-07 6.5449834979018275 0.1226167964695144 RPGNSTVTSS(ph)PPVTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPGNSTVTSSPPVTPK 16 1 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 RPGNS(0.001)T(0.001)VT(0.011)S(0.134)S(0.828)PPVT(0.025)PK;RPGNS(0.001)T(0.001)VT(0.002)S(0.207)S(0.785)PPVT(0.004)PK 65.467 0.013022999999999998 9933500.0 89590.0 85939.0 75105.0 92004.0 104116.0 78771.0 93803.0 68315.0 74280.0 62251.0 True False 104755.81751684276 94470.45596893523 76895.78803729879 86849.31416099255 83715.21720295958 74640.11009157966 84917.30076509062 66521.80363572577 75366.20447604629 73536.61352135512 1.4245395932792246 1.2846723753671483 1.0456802993106034 1.1810349974271173 1.1384154531218464 1.0150060836008457 1.1547621885039694 0.9046079286260273 1.0248800001397924 1.0 16.166175119206766 -1.5228787452803376 0.4044544586255224 1.009472330352353 7.9324734574474 0.7378276747095145 0.07445613952607306 38.18657111345309 0.502885761955647 0.053500548154874365 211.39507060457032 0.029999999999999995 1.5228787452803376 6.923001127095047 RPGNSTVTSS(ph)PPVTPK ddPTM_PC-9_Lapatinib_30min_R1 1 RPGNSTVTSSPPVTPK 16 1 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 RPGNS(0.003)T(0.003)VT(0.025)S(0.14)S(0.774)PPVT(0.055)PK 64.331 0.013930000000000001 6184500.0 52913.0 44247.0 47862.0 30365.0 37158.0 46623.0 42761.0 38396.0 37783.0 28002.0 True False 52158.45091694422 44144.54879002759 43926.97111266282 32598.14339467057 34972.43949543876 44629.04297352131 44974.95534882012 40180.01833148938 33527.48066737152 32842.108389680376 1.5881578094216817 1.3441447871202648 1.3375198264209347 0.9925715793847613 1.0648658448014798 1.3588970124568682 1.369429599804625 1.223429928881019 1.0208687051866165 1.0 15.003259127423293 -4.906518610123158 1.4979558887839528 1.1762154895419112 1.6745249229703103 0.4786401168332317 0.13874728169265296 0.8772311034728314 2.2113123363207716 0.042860225321311334 0.6101753614443072 1.2401704809486163e-05 4.906518610123158 0.49830943342839906 RPGPGTLY(ph)DVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPGPGTLYDVPR 12 1 P56945-6;A0A2R8Y6M6;A0A2R8Y5C9;A0A2R8Y8C4;A0A2R8YFS8;A0A2R8Y5E4;A0A2R8Y4C2;A0A2R8YFK2;A0A2R8Y596;P56945;P56945-8;P56945-2;P56945-3;P56945-5;P56945-7;P56945-4;H3BN62 P56945-6 BCAR1 Breast cancer anti-estrogen resistance protein 1 1 RPGPGT(0.347)LY(0.653)DVPR 75.08800000000001 0.016501 0.0 11149.0 10207.0 11868.0 13884.0 14531.0 11851.0 9654.3 11174.0 11397.0 10130.0 True False 13036.305497212608 11220.283504287016 12150.978129640633 13106.12449253532 11683.754861656298 11229.512697506834 8739.774812920865 10880.694339831647 11563.659563994326 11966.488810964125 1.0894010518163255 0.9376420837837236 1.0154171638473828 1.0952355949664216 0.9763728564181019 0.9384133370197909 0.7303541540868004 0.9092637374015982 0.9663368885114644 1.0 13.546712280527299 -6.741100000665517 3.069930822079373 0.8887874397363974 1.0258674666684497 0.3486134197015628 0.07905660210406563 0.2700837326398003 5.245584729413886 0.02905020088897261 0.027353747538654306 1.815097670186245e-07 6.741100000665517 0.13708002693205235 RPGQSFHVNSEVNSVLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 RPGQSFHVNSEVNSVLSPR 19 1 Q5T1Z4;Q5T1Z8;Q14671-2;Q14671;Q14671-3;H0YEH2 Q5T1Z4 PUM1 Pumilio homolog 1 1 RPGQSFHVNS(0.256)EVNS(0.08)VLS(0.664)PR;RPGQSFHVNSEVNS(0.041)VLS(0.959)PR;RPGQSFHVNSEVNS(0.025)VLS(0.975)PR 119.25 1.878e-05 55647000.0 29664.0 38703.1 139529.0 326449.0 217044.0 161616.0 83494.0 231221.0 112697.0 145175.0 True False 39096.53495046977 51213.12019462873 137678.754293371 251191.22663677266 186911.18705214927 151510.12597126182 90924.80425068953 195491.107379998 118653.93334451469 140092.4674378306 0.27907663891936085 0.3655665513733333 0.982770571547462 1.7930387781073582 1.3341986936956163 1.0815008739745273 0.6490342122858218 1.3954433878948693 0.8469686880000898 1.0 17.096019860739176 -5.301492021272828 3.9738483121285375 1.1699230935097849 0.30386074006759844 0.5479452225865993 0.2980662376222883 0.15773642215847772 5.429555702823707 0.08312164037582996 0.20190328454855405 4.994683562058835e-06 5.301492021272828 -0.8660623534421864 RPGQSFHVNSEVNSVLS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RPGQSFHVNSEVNSVLSPR 19 1 Q5T1Z4;Q5T1Z8;Q14671-2;Q14671;Q14671-3;H0YEH2 Q5T1Z4 PUM1 Pumilio homolog 1 1 RPGQSFHVNSEVNS(0.171)VLS(0.829)PR;RPGQSFHVNS(0.002)EVNS(0.05)VLS(0.948)PR;RPGQSFHVNSEVNS(0.418)VLS(0.582)PR 117.02 2.3615e-05 24177500.0 22477.4 14321.2 84678.0 70452.0 103514.0 107701.0 74601.0 53531.0 77731.0 46780.0 True False 26282.37987111372 15742.91409048645 86697.04466310352 66504.80284846592 83231.17478146634 102052.96996322535 67534.2532155318 52125.86797078284 78867.66882239563 55260.843689723755 0.4756058379905112 0.28488370859625484 1.5688693634481299 1.2034706386654945 1.50615099633276 1.8467501244864817 1.222099568271528 0.9432694922910869 1.4271890104541016 1.0 15.753969968078588 -5.257098181134058 24.98899205739932 1.35268352175308 0.3802446725917154 0.6873288003836743 0.25873756166503703 200.11517210639866 1151900.7769460543 0.0689981386538268 0.16971925400039134 5.532250272657182e-06 5.257098181134058 -0.9724388491613645 RPGQSFHVNSEVNSVLS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 RPGQSFHVNSEVNSVLSPR 19 1 Q5T1Z4;Q5T1Z8;Q14671-2;Q14671;Q14671-3;H0YEH2 Q5T1Z4 PUM1 Pumilio homolog 1 1 RPGQSFHVNSEVNS(0.371)VLS(0.629)PR;RPGQSFHVNSEVNS(0.251)VLS(0.749)PR 101.05 0.00015219999999999999 19370200.0 41842.0 29965.8 90266.0 36620.0 64099.0 91005.0 54480.0 58354.0 123128.0 44804.0 True False 41245.32540711697 29896.416031193272 82844.67791683633 39313.15696073887 60328.82284348269 87112.92829301636 57300.70782731272 61065.339871750446 109260.02804467942 52548.311702422674 0.7849029601690402 0.568931999195227 1.5765430940194578 0.7481335876852991 1.148063960363189 1.6577683558385403 1.0904386072725327 1.1620799582974062 2.0792300362266847 1.0 15.681356792877349 -4.7453307380203515 0.4916039629845662 1.403433342950263 0.13131378230163757 0.26046111730964683 0.3799324996364 6.548534046226801 1.1885960043734527 0.24241995899820296 4.892605019619733 1.7975015021085893e-05 4.7453307380203515 -1.2721195606486255 RPGS(ph)VSSTDQER ddPTM_PC-9_AZD4547_30min_R2 3 RPGSVSSTDQER 12 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 RPGS(0.955)VS(0.009)S(0.009)T(0.028)DQER;RPGS(0.449)VS(0.272)S(0.272)T(0.007)DQER;RPGS(0.997)VS(0.002)S(0.001)T(0.001)DQER 100.18 0.0036254 23999700.0 13805.0 10390.8 19295.899999999998 23209.0 18946.0 12976.3 11820.1 17355.399999999998 13329.3 16542.0 True False 18194.702838161928 13749.422896831224 19040.023758282907 17858.52362547552 16315.67493176507 12164.889909667856 12872.066001432173 14673.521717416725 14033.859585694718 15962.86961499294 1.1398140357591322 0.8613377937960001 1.1927694842786778 1.1187539619256244 1.0221016224075878 0.7620741259605431 0.8063754394975596 0.9192283136632771 0.8791564376691756 1.0 13.962432404993113 -6.606437786055822 6.38182507144561 0.8649412192810376 1.0708260353729526 0.4851333786008297 0.1006732410976918 0.18384242466045442 11.332254333644133 0.03343820234326808 0.03342457488080849 2.4749259762650315e-07 6.606437786055822 0.205884816091915 RPGS(ph)VSSTDQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPGSVSSTDQER 12 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 RPGS(0.999)VS(0.001)STDQER;RPGS(0.361)VS(0.306)S(0.306)T(0.027)DQER 81.904 0.01865 23276800.0 9906.7 9895.8 13504.5 12449.2 14098.3 12519.1 13700.6 11725.0 10622.5 10130.9 True False 11583.708643756052 10878.189624936167 13826.49849610145 11751.711684850965 11335.83932049336 11862.576357384 12402.779984245728 11417.231173664395 10777.833966704371 11967.55197383973 0.9679263285488349 0.9089736688601949 1.1553322288739796 0.9819645413313786 0.947214546907567 0.9912283133020687 1.0363673382290193 0.9540155913775599 0.9005880225349342 1.0 13.546840451095996 -7.9326969998656125 8.955609937733678 0.9426790643005937 0.9980507140112299 0.09492523813546239 0.06557119473137138 0.6446736702351882 78.54547273525696 0.0363888500450996 0.017424418158578498 1.1676239650320686e-08 7.9326969998656125 0.05537164971063624 RPGS(ph)VSSTDQER ddPTM_PC-9_Lapatinib_30min_R1 3 RPGSVSSTDQER 12 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 RPGS(0.907)VS(0.068)S(0.01)T(0.014)DQER;RPGS(0.59)VS(0.162)S(0.162)T(0.086)DQER;RPGS(0.577)VS(0.371)S(0.041)T(0.011)DQER 84.46799999999999 0.014972999999999998 27700800.0 22955.4 22481.6 26629.0 21521.7 26166.6 19656.1 20720.0 24284.6 25313.800000000003 21447.4 True False 22628.051786495198 22429.545236465397 24439.6664109126 23104.47761228657 24627.53203351494 18815.45442360707 21792.780216261373 25412.951171290937 22462.6932778686 25154.55451313587 0.8995608240519101 0.8916693485767178 0.971580172415697 0.9185007669375048 0.9790486259915391 0.7479939433545332 0.8663552441320733 1.0102723607376998 0.8929871235103144 1.0 14.618532019286928 -8.701202393261678 1.04468745314252 0.9964833201986807 0.9040259805422362 0.1311324409617024 0.06916885983527121 1.66576522134733 3.681570287398336 0.06865239191596158 0.022112568746973878 1.9897458461905686e-09 8.701202393261678 -0.09245733965644454 RPGSVS(ph)STDQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPGSVSSTDQER 12 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 RPGS(0.116)VS(0.542)S(0.116)T(0.226)DQER 118.51 0.00085435 2257600.0 6806.0 6311.5 7420.5 8110.3 8346.8 5842.4 6024.5 6036.5 4262.2 4922.3 True False 7958.121375372599 6938.06400874963 7597.432862402966 7655.906184947363 6711.304458005148 5536.014259042609 5453.815746397123 5878.048271200439 4324.526611709802 5814.6740250946405 1.368627259417706 1.1931991335725316 1.3065965227997987 1.3166526879935896 1.154201323933359 0.9520764595144273 0.9379400672952352 1.0108990195894545 0.7437264054779777 1.0 12.505482600081757 -6.63065275793452 2.4228110562097926 0.9239666089852812 1.2896619273829006 0.8269794369199672 0.07962013345876974 0.11418416916278529 1.3644849524815916 0.028170024675968026 0.028228059008913436 2.3407080140666036e-07 6.63065275793452 0.3656953183976195 RPGSVSSTDQER ddPTM_PC-9_Lapatinib_30min_R1 1 RPGSVSSTDQER 12 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 0 68.809 0.021283 333370.0 1004.8 1242.1 1091.2 913.35 1119.6 554.29 578.28 472.86 1037.7 1133.4 False True 990.4713677422473 1239.223993764397 1001.4857481538099 980.5208058462819 1053.7473292182906 530.5843088130994 608.2205088542294 494.8308018602995 920.8232985345637 1329.3066798394302 0.7451037317151588 0.9322333307721627 0.7533895400832421 0.7376182040736612 0.7927044565408902 0.3991436414636762 0.4575471695724102 0.3722472845168213 0.6927094495950264 1.0 10.376458266960157 -6.739874085554275 24.555888078552687 0.5371710978674175 0.794799520130419 0.2338894640563295 0.17814062164517624 221.47336316731818 252185.65450618 0.05606659864251967 0.056013789786269835 1.8202285186493147e-07 6.739874085554275 0.25762842226300153 RPHPQHSQQPPPPQQER ddPTM_PC-9_AZD4547_30min_R2 1 RPHPQHSQQPPPPQQER 17 1 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;H7C3Z6;O95819-6;E7EN19 C9J840;O95819-6;E7EN19 MAP4K4 0 52.008 0.015072 328510.0 0.0 0.0 607.3 0.0 559.21 633.41 396.84 384.63 565.38 553.78 False True 0.0 0.0 599.2468051972289 0.0 481.57334416723046 593.802772568661 432.15799121905417 325.19427141811735 595.2648325538535 534.3923307575133 0.0 0.0 1.1213611624025048 0.0 0.9011606575352407 1.111173829397836 0.8086904814042903 0.6085309475851705 1.1139097593523695 1.0 9.061755493137781 -5.534842673849546 0.8010704663761791 0.9043465211298806 1.5878859725361555e-21 0.4550398025311675 0.3404874150231711 1.1378827288904925 1.111611375256273 0.14993556998603114 0.7636678221129197 2.918484063367911e-06 5.534842673849546 -0.9043465211298806 RPHT(ph)PTPGIYMGR ddPTM_PC-9_Lapatinib_30min_R1 3 RPHTPTPGIYMGR 13 1 P62995;H7C2L4;P62995-3;H7BXF3 P62995 TRA2B Transformer-2 protein homolog beta 1 RPHT(0.801)PT(0.199)PGIYMGR;RPHT(0.98)PT(0.02)PGIYMGR;RPHT(0.992)PT(0.008)PGIYMGR 77.324 0.013791999999999999 105724000.0 5519.1 20476.5 13259.8 11247.3 11794.5 15758.900000000001 14166.2 11322.7 16321.6 15530.7 True False 5440.396621921019 20429.087922322396 12169.630428308184 12074.46396189292 11100.770698879178 15084.92858279015 14899.656520251057 11848.79397754856 14483.289533932488 18215.16080164307 0.29867409248620397 1.1215431005407113 0.6681044741153448 0.6628798995177557 0.6094247983733336 0.8281523697243144 0.817981058882942 0.650490770110564 0.795122793130986 1.0 14.152852110655894 -14.522878680830866 0.21527860493060896 2.353108569065981 0.6907367735824463 0.17525855369257126 0.19493326555553886 282.11492982535873 2.8113488473799735 165.03787784935093 0.3727676793631681 3.0000004452012114e-15 14.522878680830866 -1.6623717954835349 RPILQLS(ph)PPGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPILQLSPPGPR 12 1 Q8N3X1-2;Q8N3X1;F5GXL1 Q8N3X1-2 FNBP4 Formin-binding protein 4 1 RPILQLS(1)PPGPR;RPILQLS(1)PPGPR 99.927 0.0014637 17294500.0 12566.2 13336.1 14234.2 13660.3 17506.7 16954.6 14619.599999999999 10570.5 14113.0 11314.0 True False 14693.40946623672 14660.019872785542 14573.59731150412 12894.957678290135 14076.387807897481 16065.47092913251 13234.725651261908 10293.035575370533 14319.375925827138 13365.138638425284 1.0993832435072994 1.0968849833429655 1.0904187158675984 0.9648203454632815 1.0532167446005631 1.2020429689328975 0.9902423019549955 0.7701405764529567 1.0713974851453008 1.0 13.706187182482573 -7.516388865892418 24.97275386939353 0.9284997069063751 1.0799136336706203 0.32494601910424625 0.08958900251313125 312.63381797298183 1203014.8125839024 0.03959175443815942 0.023912853536881225 3.045167135624162e-08 7.516388865892418 0.15141392676424525 RPILQLS(ph)PPGPR ddPTM_PC-9_Lapatinib_30min_R1 2 RPILQLSPPGPR 12 1 Q8N3X1-2;Q8N3X1;F5GXL1 Q8N3X1-2 FNBP4 Formin-binding protein 4 1 RPILQLS(1)PPGPR;RPILQLS(1)PPGPR 78.40100000000001 0.031397 69633000.0 33787.7 27480.4 30816.9 28197.8 27002.8 20419.4 18308.1 24721.9 29568.7 24626.7 True False 33305.881202094686 27416.770822190756 28283.25343867408 30271.56027710329 25414.54839354741 19546.109861946272 19256.003835778716 25870.56972573307 26238.361633785255 28883.39228198491 1.153115287738143 0.9492226728261101 0.9792220097469249 1.0480611135134636 0.8799017838842608 0.6767248691261771 0.6666808263996411 0.8956901416967219 0.9084238228537509 1.0 14.817952572639838 -6.405982671692062 4.320295585528603 0.8097596038628737 1.021668417521071 0.4335883167234449 0.10828214085044087 0.2221363473319988 6.826405413567916 0.035765683392373876 0.040505242971429 3.926606022071998e-07 6.405982671692062 0.21190881365819736 RPIS(ph)DDDCPSASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPISDDDCPSASK 13 1 Q96PU4 Q96PU4 UHRF2 E3 ubiquitin-protein ligase UHRF2 1 RPIS(0.997)DDDCPS(0.003)ASK;RPIS(0.968)DDDCPS(0.029)AS(0.004)K 89.866 0.010274 0.0 10399.900000000001 13845.9 11917.5 12982.6 15431.8 12954.400000000001 13599.8 14140.8 14456.2 11851.0 True False 12160.397662612033 15220.429447634719 12201.658397370433 12255.227012157091 12408.049568103203 12275.048459082147 12311.52848997453 13769.618983416074 14667.594576556532 13999.492487535616 0.8686313217024823 1.0872129444111034 0.8715786238846961 0.8754050922251987 0.8863213848038172 0.8768209611892132 0.8794267721444933 0.9835798687470844 1.0477233077996047 1.0 13.773086906792043 -7.932791949449731 4.689812982815139 1.0220523990861616 0.909313846281026 0.3736098014664091 0.06292408870820267 0.22637737703301558 9.579122310208538 0.03846899936392096 0.017314204046747585 1.1673687158954463e-08 7.932791949449731 -0.11273855280513567 RPIS(ph)DDDCPSASK ddPTM_PC-9_Lapatinib_30min_R1 2 RPISDDDCPSASK 13 1 Q96PU4 Q96PU4 UHRF2 E3 ubiquitin-protein ligase UHRF2 1 RPIS(1)DDDCPSASK;RPIS(0.966)DDDCPS(0.031)AS(0.003)K 111.34 0.00084644 8245700.0 27903.7 28246.6 33578.2 32245.4 33263.0 31255.9 30786.2 31332.8 32838.4 28207.4 True False 27505.78812108812 28181.196733165933 30817.530011600324 34616.834283501084 31306.535737574144 29919.15801806155 32380.158797966484 32788.63627401007 29139.793588317825 33083.01150600207 0.8314173005712584 0.8518328728342391 0.9315213037969433 1.0463628523425306 0.9463024770853878 0.9043662186749075 0.9787548752051164 0.9911019215424631 0.8808083745045747 1.0 15.013802946798151 -5.3009883703206295 3.5844176532332295 0.9624785848393057 0.8377497505193272 0.5349188351278105 0.044893122252566725 0.17188564954521468 4.608747069789739 0.012037882774298205 0.0305044607224414 5.0004792524422845e-06 5.3009883703206295 -0.1247288343199785 RPISDDDCPS(ph)ASK ddPTM_PC-9_Lapatinib_30min_R1 1 RPISDDDCPSASK 13 1 Q96PU4 Q96PU4 UHRF2 E3 ubiquitin-protein ligase UHRF2 1 RPIS(0.17)DDDCPS(0.825)AS(0.005)K 125.36 0.00020936 6324400.0 25798.0 30023.0 28230.0 29730.0 31406.0 25224.0 31723.0 28668.0 29584.0 21141.0 True False 25430.11578922621 29953.48358810761 25909.038370951315 31916.44337637268 29558.760826571677 24145.22832001591 33365.461718168895 30000.01993767939 26251.93838666911 24795.19368138821 1.0256066605486767 1.2080358787675582 1.0449217983079995 1.2872028259383927 1.1921165531672817 0.9737866390670634 1.3456423106391666 1.209912708211593 1.0587510920059626 1.0 14.597772874192502 -4.746696587128959 24.364225060835913 1.1567091278325903 1.0256061849955562 0.08099098945256877 0.11813283855065633 1415.4748054113047 2339056.77610497 0.028287917926306312 0.6031942534364979 1.7918572691725955e-05 4.746696587128959 -0.13110294283703405 RPLDS(ph)PEAEELPAMK ddPTM_PC-9_Lapatinib_30min_R1 3 RPLDSPEAEELPAMK 15 1 Q5VWG9 Q5VWG9 TAF3 Transcription initiation factor TFIID subunit 3 1 RPLDS(1)PEAEELPAMK;RPLDS(1)PEAEELPAMK;RPLDS(1)PEAEELPAMK 91.065 0.0018442 10732000.0 89826.0 73117.0 86960.0 70681.0 89622.0 78576.0 75338.0 70847.0 80020.0 64802.0 True False 88545.06476792917 72947.70207879508 79810.48447530744 75879.11652490414 84350.61016363128 75215.48764960238 79238.63300833481 74138.8102596891 71007.3049520437 76002.93935676267 1.1650215836034046 0.9598010642242912 1.0500973403235356 0.9983708152223258 1.1098335258809413 0.9896391940387471 1.0425732699150436 0.9754729341674112 0.9342705104960595 1.0 16.21376759433492 -7.804689264713785 4.46183312107905 0.9635158041689564 1.0407925521592727 0.25904138435909074 0.05787139907599363 0.2777843287921256 11.891021853433935 0.030650834290441718 0.014577301979448091 1.5678724729152903e-08 7.804689264713785 0.07727674799031625 RPLEEDFRRS(ph)PTEDFR ddPTM_PC-9_AZD4547_30min_R2 1 RPLEEDFRRSPTEDFR 16 3 Q8IXT5 Q8IXT5 RBM12B RNA-binding protein 12B 1 RPLEEDFRRS(0.921)PT(0.079)EDFR 66.797 0.021537 20869000.0 44702.0 28726.0 58770.0 86719.0 80508.0 50712.0 37473.0 47648.0 38220.0 59294.0 True False 58916.30614063846 38011.1177324531 57990.67140036416 66727.27434519416 69330.85386923578 47540.97062329605 40808.024405179945 40285.096442114394 40240.23117232357 57218.13510768898 1.029678895157163 0.6643194095877684 1.0135015985966898 1.1661910025485496 1.2116937005854826 0.8308724241679715 0.7132008816501284 0.704061681952666 0.7032775726889443 1.0 15.804184856680429 -6.984066336707118 24.014160574731253 0.7578396378026825 1.0071366931280812 0.33738287911323606 0.15865608796750247 179.3162433109459 270251.7677857286 0.05988656307889403 0.052796488880361966 1.0373699496957847e-07 6.984066336707118 0.2492970553253987 RPLEEDFRRS(ph)PTEDFR ddPTM_PC-9_Lapatinib_30min_R1 1 RPLEEDFRRSPTEDFR 16 3 Q8IXT5 Q8IXT5 RBM12B RNA-binding protein 12B 1 RPLEEDFRRS(0.919)PT(0.081)EDFR 65.704 0.023107 16432000.0 29219.0 15296.0 26394.0 22483.0 20034.0 22999.0 15358.0 14330.0 24027.0 20570.0 True False 28802.33170189165 15260.583051783431 24223.987203786357 24136.47482108937 18855.63950835946 22015.386383287558 16153.162092728866 14995.824114236972 21320.826244473308 24125.49709219787 1.1938544350742624 0.6325499944504218 1.004082407554634 1.0004550260187197 0.7815648082317579 0.9125360733150357 0.6695473270871074 0.6215757568405331 0.8837466089504292 1.0 14.558271048150289 -6.618944637537213 1.7582009962352312 0.7745353686428496 0.9335312536253523 0.11440993544665978 0.16961920288431634 0.7071070440428087 4.4829944493158855 0.06551369489930885 0.06655765200892533 2.40466931997497e-07 6.618944637537213 0.15899588498250272 RPLLPFETEVGPCGVGEAS(ph)LDKADSEGSNSGGTWPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPLLPFETEVGPCGVGEASLDKADSEGSNSGGTWPK 36 2 Q8TDM6-4;Q8TDM6;Q8TDM6-3 Q8TDM6-4 DLG5 Disks large homolog 5 1 RPLLPFETEVGPCGVGEAS(0.522)LDKADS(0.119)EGS(0.119)NS(0.119)GGT(0.119)WPK 57.496 0.00012403 5280800.0 14580.0 12715.0 12365.0 12591.0 17506.0 12048.0 14978.0 15074.0 10864.0 11280.0 True False 17048.10603187371 13977.261169492445 12659.828494523641 11885.567090572771 14075.824967872497 11416.181670708154 13559.175408670611 14678.323472223217 11022.865447331262 13324.974707569127 1.279410010601348 1.048952172611089 0.9500827410450802 0.8919767092556871 1.0563490945972946 0.8567507197010512 1.0175760709675832 1.101564828028179 0.8272334986924835 1.0 13.701845174124953 -4.781559709697627 2.5847329594048256 0.9658193265733128 1.3454655529860386 0.5748237913134566 0.08214495920861663 0.35060113750997984 3.0346569649300004 0.020543247552603002 0.29557812257049587 1.653637416056978e-05 4.781559709697627 0.37964622641272583 RPLPGPS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 1 RPLPGPSPPR 10 1 O14924-5;O14924-4;O14924;E9PBG5 O14924-5 RGS12 Regulator of G-protein signaling 12 1 RPLPGPS(1)PPR 62.732 0.026692 5225300.0 7134.1 8045.0 8892.1 18099.0 13240.0 8649.2 10541.0 13746.0 10049.0 13218.0 True False 9402.595401501696 10645.388921450425 8774.184944005077 13926.55517676253 11401.854539035648 8108.364156708709 11479.128579377206 11621.871551655982 10580.169624559894 12755.241843246074 0.7371553998782382 0.8345893439164527 0.6878885600002187 1.0918299588444627 0.8938955983083107 0.6356887824123933 0.8999538166699228 0.9111447430383129 0.8294762070828249 1.0 13.638802632683804 -14.522878745277973 0.10874556645160646 1.4966662431717275 0.7479399808922873 0.16042427714193763 0.12110826320456637 357.15847229615275 2.5803214058074615 39.9200574068079 1.6354630208839533 3.0000000000163332e-15 14.522878745277973 -0.7487262622794402 RPLPGPS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 1 RPLPGPSPPR 10 1 O14924-5;O14924-4;O14924;E9PBG5 O14924-5 RGS12 Regulator of G-protein signaling 12 1 RPLPGPS(1)PPR 59.225 0.033687 3769100.0 9760.7 8691.3 11643.0 9231.8 8757.1 10153.0 8318.2 9056.8 11945.0 8129.7 True False 9621.510628106842 8671.175828841882 10685.757483279709 9910.737368382004 8242.02459512102 9718.779857798982 8748.875694734814 9477.611991473925 10599.628313573641 9534.907812855668 1.0090827113330252 0.9094137037330094 1.1206985629029764 1.0394161708642442 0.8644052734320632 1.0192840925735436 0.9175626934681982 0.993990941233381 1.1116655264650213 1.0 13.219003274738776 -8.064366360278857 11.255823393024476 1.0549850895295632 0.9823058532123797 0.13303933902322762 0.07357997672007537 1.8956814412598892 326.60142841923596 0.049573150199449904 0.018740157796182287 8.622508669900571e-09 8.064366360278857 -0.07267923631718343 RPLPVES(ph)PDTQR ddPTM_PC-9_AZD4547_30min_R2 1 RPLPVESPDTQR 12 1 P57682 P57682 KLF3 Krueppel-like factor 3 1 RPLPVES(0.676)PDT(0.324)QR 108.14 0.00067299 13560000.0 41465.0 44000.0 52090.0 57030.0 50384.0 54252.0 50764.0 57987.0 52108.0 41412.0 True False 54650.00747442114 58222.139533103626 51399.2525649986 43882.61460471666 43389.05129114595 50859.61386368229 55281.89765710126 49026.441558698934 54862.322499409645 39962.178484831784 1.367543250805617 1.4569310718434099 1.28619746254594 1.098103663727265 1.0857529027756805 1.2726937267192973 1.3833554564119745 1.226821044736278 1.3728561499777452 1.0 15.286347611418437 -11.788322123269948 2.092936974209614 1.9286315876472363e-05 1.2782535251411404 0.35278559432651646 0.11495399396707628 4416600.564373594 607159.2016001468 20917560.959217876 0.031856394402302556 1.6280880053754811e-12 11.788322123269948 1.2782342388252639 RPLPVES(ph)PDTQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RPLPVESPDTQR 12 1 P57682 P57682 KLF3 Krueppel-like factor 3 1 RPLPVES(0.827)PDT(0.173)QR;RPLPVES(0.982)PDT(0.018)QR;RPLPVES(0.984)PDT(0.016)QR 91.789 0.0028485 32739000.0 67010.0 64757.0 65639.0 79348.0 83381.0 72422.0 77766.0 71555.0 66059.0 60497.0 True False 78353.46949217112 71185.64699589637 67204.08269729359 74902.3888096869 67043.09160551679 68624.06282835545 70399.4415029162 69676.75706878929 67024.98790365033 71464.6272060116 1.096395133585473 0.9960962475979758 0.9403824706671161 1.0481043802798444 0.9381297325213939 0.9602521626612893 0.9850949239541293 0.9749824464616822 0.9378764085683523 1.0 16.12494170840467 -4.782344626611187 3.6538650695806396 0.9732739514073123 1.1098419116452054 0.5699530995133847 0.03198265800999949 0.18554617751680907 4.251729901872843 0.0077346454472730424 0.06932921420312697 1.650651433495162e-05 4.782344626611187 0.13656796023789308 RPLPVES(ph)PDTQR ddPTM_PC-9_Lapatinib_30min_R1 3 RPLPVESPDTQR 12 1 P57682 P57682 KLF3 Krueppel-like factor 3 1 RPLPVES(0.818)PDT(0.182)QR;RPLPVES(0.995)PDT(0.005)QR;RPLPVES(0.849)PDT(0.151)QR 94.339 0.0022645 46159000.0 208693.0 266425.0 308831.0 262174.0 288541.0 279645.0 265476.0 294498.0 317130.0 218881.0 True False 205716.99955039093 265808.1092816027 283440.10730213433 281455.1505468262 271569.58567343274 267685.2352343345 279221.04829595546 308181.45219780604 281411.4798730521 256714.28920940054 0.801346119781391 1.0354238951801564 1.1041072476917468 1.0963750845876938 1.057867041642995 1.0427360162097756 1.0876724048196487 1.2004842159231113 1.0962049706687975 1.0 17.969804075756436 -4.755755626526276 2.909352490139564 1.090413639414417 0.7405112811126685 0.7502020212303824 0.048940494390577786 0.2217063908078052 2.508131151493039 0.012997088168964482 0.19087141031283084 1.754867671829786e-05 4.755755626526276 -0.34990235830174854 RPLS(ph)ASLGQLNEVGLPSAAILPDEGAVDLPSR ddPTM_PC-9_AZD4547_30min_R2 1 RPLSASLGQLNEVGLPSAAILPDEGAVDLPSR 32 1 Q5TC82-2;Q5TC82 Q5TC82-2 RC3H1 Roquin-1 1 RPLS(0.5)AS(0.5)LGQLNEVGLPS(0.001)AAILPDEGAVDLPSR 48.867 0.0049851999999999995 11451000.0 11535.0 11354.0 10273.0 19952.0 18570.0 10188.0 15493.0 23832.0 11651.0 16218.0 True False 15202.89005709509 15023.95846042861 10136.773307741036 15352.374655327154 15991.87604153264 9550.942749450624 16871.84698608206 20149.312004878895 12266.848074012074 15650.21275637502 0.9714174684879145 0.9599842950575027 0.6477083388921906 0.9809690701535962 1.021831223030399 0.6102755852670504 1.078058634008628 1.2874784719250028 0.7838135024084735 1.0 13.933894649517617 RPLS(ph)ASLGQLNEVGLPSAAILPDEGAVDLPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPLSASLGQLNEVGLPSAAILPDEGAVDLPSR 32 1 Q5TC82-2;Q5TC82 Q5TC82-2 RC3H1 Roquin-1 1 RPLS(0.5)AS(0.5)LGQLNEVGLPSAAILPDEGAVDLPSR 72.196 7.3858000000000005e-06 13051000.0 16603.0 15911.0 25707.0 21390.0 33765.0 31748.0 26013.0 22702.0 22682.0 22016.0 True False 19413.55997580241 17490.538927864283 26319.952374340417 20191.58764731566 27148.99063408057 30083.078990840175 23548.86032218912 22106.096554757292 23013.68133987183 26007.326521439893 0.746465037834561 0.6725235257628442 1.012020683965451 0.7763807491196814 1.0438977882520724 1.1567155495986994 0.905470245193251 0.8499949634013128 0.8848922368433308 1.0 14.666630481540896 -6.25254913214954 24.870390377773596 0.9717546560871227 0.8076224357635692 0.3488150441611797 0.11477095816176973 815.0183617683132 2280005.171885316 0.03706343791979798 0.04713221308791629 5.590502781009704e-07 6.25254913214954 -0.16413222032355357 RPLS(ph)GPDVGTPQPAGLASGAK ddPTM_PC-9_AZD4547_30min_R2 4 RPLSGPDVGTPQPAGLASGAK 21 1 O96013 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 RPLS(0.69)GPDVGT(0.309)PQPAGLAS(0.001)GAK;RPLS(1)GPDVGTPQPAGLASGAK;RPLS(0.993)GPDVGT(0.007)PQPAGLASGAK;RPLS(0.981)GPDVGT(0.019)PQPAGLASGAK 135.69 3.201e-05 78790500.0 73008.0 90264.9 122624.0 164598.0 135760.0 132882.0 135839.0 163465.0 123774.8 140625.0 True False 96223.0253392628 119441.26369867376 120997.92563890171 126652.4741137498 116912.06738817833 124572.86753361806 147928.40784498834 138205.24030201085 130317.2832367376 135701.76155291853 0.7090772016377951 0.8801747474154653 0.8916459466277239 0.933314885999915 0.8615368441078568 0.9179900548677798 1.0900993926103302 1.0184483879976463 0.9603212349304604 1.0 17.05007992302825 -3.141853220581335 0.339410900532999 1.0159356118470664 1.0043300261276904e-17 0.6907229593729749 0.05469795005096026 12.797408361565951 0.48859357580303786 0.05394438881912791 6.66955538938415 0.0007213512345818989 3.141853220581335 -1.0159356118470664 RPLS(ph)GPDVGTPQPAGLASGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPLSGPDVGTPQPAGLASGAK 21 1 O96013 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 RPLS(0.998)GPDVGT(0.002)PQPAGLASGAK;RPLS(0.996)GPDVGT(0.004)PQPAGLASGAK 88.071 0.00021059 44537100.0 56265.0 64470.0 59629.0 63098.0 81446.0 63399.0 82436.0 62810.0 65296.0 50415.4 True False 65789.55321559487 70870.15553261328 61050.781504241815 59562.82362647611 65487.24096500301 60074.244832439086 74627.06529504406 61161.30405269599 66250.83047210437 59555.31293191321 1.1046798342040276 1.1899888027393255 1.0251105820573607 1.0001261129224772 1.0996036749881826 1.008713444275226 1.2530714997730206 1.0269663786775636 1.112425192826135 1.0 15.86194259626384 -5.2603266302054905 24.99570130468789 1.0702332777966157 1.1473343162455265 0.15483248020970708 0.07566499016806674 187.21088484080857 4205142.531291532 0.01923831363384271 0.04546915218884154 5.491277229340302e-06 5.2603266302054905 0.07710103844891081 RPLS(ph)GPDVGTPQPAGLASGAK ddPTM_PC-9_Lapatinib_30min_R1 2 RPLSGPDVGTPQPAGLASGAK 21 1 O96013 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 RPLS(0.999)GPDVGT(0.001)PQPAGLASGAK;RPLS(0.795)GPDVGT(0.205)PQPAGLASGAK 112.34 7.8388e-06 69444000.0 96477.0 131433.0 154069.0 129949.0 164658.0 161512.0 159363.0 170221.0 169946.0 126766.0 True False 95101.22028828508 131128.6749637193 141402.04154353845 139505.8829571561 154973.1401700833 154604.50826286097 167614.0363708525 178130.0890823123 150804.8918692831 148677.33419492247 0.6396484091085682 0.8819681606061344 0.9510665651171429 0.938313050288202 1.0423454322022396 1.0398660232915375 1.12736778123223 1.19809848654386 1.0143098992585602 1.0 17.181825200260256 -4.1374579880343365 0.5637657206691928 1.092077755243792 1.324172256272024e-17 0.8097693354324818 0.06263758473853948 3.154794315384432 0.446195592944174 0.032896628256771386 2.63997782418819 7.286886616219342e-05 4.1374579880343365 -1.092077755243792 RPLS(ph)PETR ddPTM_PC-9_AZD4547_30min_R2 2 RPLSPETR 8 1 Q9P227 Q9P227 ARHGAP23 Rho GTPase-activating protein 23 1 RPLS(0.994)PET(0.006)R;RPLS(0.997)PET(0.003)R 83.397 0.0069281 9387400.0 16066.900000000001 11471.1 18069.2 17649.1 18083.1 18588.0 13069.0 19496.3 15229.5 12300.3 True False 21175.83998771921 15178.908745413306 17829.59060179446 13580.372670876817 15572.57370202686 17425.689421553616 14232.115681992283 16483.594815404518 16034.500278359541 11869.670240919942 1.7840293418360378 1.2787978467240793 1.5021133898335328 1.144123837919215 1.3119634653658188 1.4680853863555237 1.1990321039356222 1.3887154807871882 1.3508800120732596 1.0 13.534992234630543 -1.522878747057123 0.03267261129474909 4.584171571168499e-10 3.3515969545086093 0.40485288726535307 0.15822116943378592 1324.8282992689624 3.3259364813013996 104.56167686007394 273.6196746160647 0.02999999987726401 1.522878747057123 3.351596954050192 RPLS(ph)PETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RPLSPETR 8 1 Q9P227 Q9P227 ARHGAP23 Rho GTPase-activating protein 23 1 RPLS(0.835)PET(0.165)R;RPLS(0.855)PET(0.145)R;RPLS(0.999)PET(0.001)R 86.31299999999999 0.005762300000000001 13389500.0 21300.5 28845.7 33233.8 26574.0 39460.0 27518.0 28065.699999999997 23767.2 24147.899999999998 22416.8 True False 24906.253945948265 31709.310461410005 34026.219831888375 25085.144934070424 31728.096265980133 26074.9076373296 25407.113717928074 23143.336183429983 24501.01735416149 26480.788388708854 0.9405404997899551 1.1974458613524717 1.2849398338305071 0.9472960006268726 1.1981552739384709 0.9846726334042111 0.9594545806182045 0.8739670376769474 0.92523745873852 1.0 14.692658454396579 -6.926648617966102 5.234107172501451 0.934382560607549 1.1181942228052295 0.3860078283817514 0.10494970679587176 0.20754040514864322 10.345329573360118 0.037563553454093415 0.03288506873773962 1.1839991266345028e-07 6.926648617966102 0.18381166219768053 RPLS(ph)PETR ddPTM_PC-9_Lapatinib_30min_R1 1 RPLSPETR 8 1 Q9P227 Q9P227 ARHGAP23 Rho GTPase-activating protein 23 1 RPLS(0.979)PET(0.021)R 73.9 0.013152 3900500.0 5234.3 5643.5 4392.7 5130.9 6265.5 3967.2 3849.2 5232.1 5605.6 5755.5 True False 5159.657922146942 5630.432822485604 4031.5491623123544 5508.243502180644 5896.975608446949 3797.532103994891 4048.49274171975 5475.2024667201185 4974.2382984151 6750.330506278315 0.7643563403818632 0.8340973552700685 0.5972372995015148 0.8159961200503536 0.8735832420297522 0.5625698031322911 0.5997473365125378 0.8111013914989449 0.7368881114470891 1.0 12.720742425061943 -9.176554591891986 1.4462805448580032 0.9999980000668687 0.7288907427530638 0.3706139324033858 0.10448029804721874 5.852634490537696 11.813574266658366 0.10471963386826638 0.030266147956017873 6.659558037428885e-10 9.176554591891986 -0.2711072573138049 RPLS(ph)SSHEASEGQAK ddPTM_PC-9_AZD4547_30min_R2 3 RPLSSSHEASEGQAK 15 1 A0A0J9YVR0;Q8IZ21-3;Q8IZ21;Q8IZ21-2 A0A0J9YVR0;Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 RPLS(0.333)S(0.333)S(0.333)HEASEGQAK;RPLS(0.47)S(0.173)S(0.357)HEASEGQAK;RPLS(0.333)S(0.333)S(0.333)HEAS(0.002)EGQAK 64.89 0.012846000000000002 34308600.0 63610.0 63195.6 162816.0 248899.0 221361.0 208235.0 128469.0 245596.0 159037.0 195723.0 True False 83836.6568298066 83622.34184268661 160656.9534579154 191519.18100121655 190628.84611899307 195214.03253159157 139902.49212256965 207644.7814346359 167443.3711395295 188870.7973434445 0.4438836390220623 0.4427489215848808 0.8506182835972003 1.0140221976876405 1.0093082085757903 1.0335850500838013 0.7407311987367194 1.0994012010075471 0.8865498186839804 1.0 17.52704012807058 -5.331716862172637 3.2528797683939223 0.9667887138391127 0.43012352032584206 0.832474226386319 0.09285798677436612 0.08691341727206137 1.7850999062189834 0.024381718876697378 0.06184925331770704 4.658897308506273e-06 5.331716862172637 -0.5366651935132707 down RPLS(ph)SSHEASEGQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPLSSSHEASEGQAK 15 1 A0A0J9YVR0;Q8IZ21-3;Q8IZ21;Q8IZ21-2 A0A0J9YVR0;Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 RPLS(0.461)S(0.461)S(0.077)HEASEGQAK;RPLS(0.423)S(0.423)S(0.153)HEASEGQAK 76.068 0.0065674999999999996 12864800.0 38846.0 45064.0 91961.0 97358.0 122501.0 103115.0 115243.0 96308.0 97432.0 78737.0 True False 45421.860556527135 49537.65610239933 94153.69900403485 91903.34689889482 98497.80843078632 97707.467876417 104326.34875293296 93780.01704676071 98856.7586767655 93011.39481825089 0.488347268044779 0.5325977123469494 1.01228133593756 0.9880869658871232 1.0589864674458023 1.0504892230392038 1.1216512660281257 1.0082637426308008 1.0628456746610107 1.0 16.505119851047063 -5.259103439118544 4.192693436868746 1.0436933999693827 0.49513687510396664 0.9715559092907863 0.036157774003841944 0.028698928026584504 1.2614585641052376 0.009874525074656668 0.025574125942910853 5.506765220975767e-06 5.259103439118544 -0.5485565248654161 down RPLS(ph)SSHEASEGQAK ddPTM_PC-9_Lapatinib_30min_R1 2 RPLSSSHEASEGQAK 15 1 A0A0J9YVR0;Q8IZ21-3;Q8IZ21;Q8IZ21-2 A0A0J9YVR0;Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 RPLS(0.708)S(0.217)S(0.068)HEAS(0.007)EGQAK;RPLS(0.715)S(0.218)S(0.067)HEASEGQAK 77.03699999999999 0.0061123 17368000.0 81296.8 83406.0 190201.0 84214.0 129546.0 145069.0 93588.0 102453.9 169806.0 99854.0 True False 80137.4927239928 83212.8785314493 174563.40797709228 90407.37848966882 121926.35897723552 138864.7370423561 98433.52871039916 107214.28222035061 150680.66014354845 117113.63085290839 0.6842712683431645 0.7105311134616129 1.4905473146532302 0.7719629033038697 1.0410945172588133 1.1857265122005014 0.8404959183105599 0.9154722762801958 1.2866193204512577 1.0 16.83754947529247 -5.049539319681324 24.999983649709588 1.0517196489167986 0.6908340816407669 0.34560182299380326 0.2024793690714854 346.00226814831683 174609.61958891805 0.04936965530677188 0.1306249298201299 8.92196839184292e-06 5.049539319681324 -0.3608855672760317 RPLSAS(ph)LGQLNEVGLPSAAILPDEGAVDLPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPLSASLGQLNEVGLPSAAILPDEGAVDLPSR 32 1 Q5TC82-2;Q5TC82 Q5TC82-2 RC3H1 Roquin-1 1 RPLS(0.267)AS(0.725)LGQLNEVGLPS(0.008)AAILPDEGAVDLPSR 52.547 0.0020500999999999996 11087000.0 18076.0 22427.0 31411.0 30003.0 34469.0 33331.0 36046.0 28015.0 27634.0 21481.0 True False 21135.90978272628 24653.404345120507 32159.95736688086 28322.029181038433 27715.04688778685 31583.063684127934 32631.461929559424 27279.63593434612 28038.094971608247 25375.335256497576 0.8329312526940603 0.9715498966189141 1.267370737836696 1.1161243347035712 1.092204166275603 1.2446363117918142 1.2859519529383894 1.0750453406270142 1.1049349570437241 1.0 14.631139262721799 -5.034488845857534 4.264392197652419 1.155736087465385 0.8538934249634672 0.5753115518731229 0.0879878773193143 0.13019188912999397 5.3522839495007455 0.022744558374032026 0.07908075072049629 9.236579107556354e-06 5.034488845857534 -0.3018426625019178 RPLSPET(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 RPLSPETR 8 1 Q9P227 Q9P227 ARHGAP23 Rho GTPase-activating protein 23 1 RPLS(0.279)PET(0.721)R 64.82 0.045391 4888600.0 4349.5 6203.5 6409.2 4719.9 7075.8 5637.3 6410.5 4316.0 6575.5 6589.5 True False 4287.4753323993855 6189.136176891906 5882.260316227458 5067.0171911248335 6659.615355558041 5396.205820188137 6742.404323182605 4516.53711633264 5834.8979469153155 7728.486295043168 0.5547626234582639 0.8008212657194518 0.7611141550448467 0.6556286700507802 0.861697245918561 0.6982228620433876 0.8724094299690992 0.5844012583977044 0.754985869698398 1.0 12.915970159551911 -12.076336923910347 1.8610603930179113 3.87905396475869 0.7313653841655752 0.39414390174241887 0.10137470372116646 4238811.543009525 219229.1912716699 51493609.97043527 0.02415791630797366 8.38808989395118e-13 12.076336923910347 -3.147688580593115 RPLSS(ph)SHEASEGQAK ddPTM_PC-9_Lapatinib_30min_R1 1 RPLSSSHEASEGQAK 15 1 A0A0J9YVR0;Q8IZ21-3;Q8IZ21;Q8IZ21-2 A0A0J9YVR0;Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 RPLS(0.255)S(0.373)S(0.373)HEASEGQAK 51.643 0.041687 16582000.0 54602.0 54697.0 103210.0 50425.0 91498.0 98742.0 67066.0 73946.0 114830.0 58317.0 True False 53823.365467219555 54570.35245707367 94724.47220212118 54133.422712868865 86116.26753198919 94519.03483884437 70538.34932354171 77381.80111314512 101896.63618649308 68397.01574748187 0.7869256411117781 0.7978469800282588 1.3849211280187848 0.7914588395599973 1.2590646915053407 1.38191752675005 1.0313074123579533 1.1313622424527203 1.4897819016357383 1.0 16.061645759335597 -5.238564642820243 23.361201521135413 1.1787339799372334 0.7923859509134741 0.3838744273544822 0.1982338855260373 352.7063611706487 360203.25036609865 0.04911611529391487 0.12967755062122335 5.773449310687688e-06 5.238564642820243 -0.3863480290237593 RPMDLS(ph)IIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPMDLSIIR 9 1 B5MCJ9;A0A2R8YEA1;O15016-2;O15016;H0YF52 B5MCJ9 TRIM66 Tripartite motif-containing protein 66 1 RPMDLS(1)IIR 60.828 0.025461 9474300.0 34094.0 36747.0 34398.0 43197.0 38719.0 33213.0 32191.0 31003.0 28560.0 30984.0 True False 39865.44081280537 40394.99930753749 35218.17877514143 40776.81213656354 31132.28989666713 31471.251811855058 29141.635437342484 30189.204100393796 28977.635969788364 36601.153930790955 1.0891853543248076 1.103653709495616 0.9622149848536309 1.1140854251116872 0.8505821962754265 0.8598431588076152 0.7961944449195876 0.8248156371648419 0.7917137264191756 1.0 15.159601512867145 -6.271578907195213 23.88973302303267 0.8425150115112665 1.0623776492619776 0.7052122998291804 0.0673313616111149 194.72780108177665 458797.01775873656 0.019929377860596176 0.022880372341015743 5.350829254377398e-07 6.271578907195213 0.21986263775071113 RPMDLS(ph)IIR ddPTM_PC-9_Lapatinib_30min_R1 1 RPMDLSIIR 9 1 B5MCJ9;A0A2R8YEA1;O15016-2;O15016;H0YF52 B5MCJ9 TRIM66 Tripartite motif-containing protein 66 1 RPMDLS(1)IIR 104.01 0.0012522 2471500.0 14905.0 10133.0 11832.0 8720.5 12593.0 11536.0 8140.8 9718.3 11059.0 11002.0 True False 14692.451966757755 10109.537661069658 10859.218632840804 9361.834660735207 11852.304498790585 11042.632171729438 8562.29079075968 10169.84769639841 9813.41896356726 12903.681040756503 1.1386248559888754 0.7834615276941911 0.8415597532627916 0.7255165895038546 0.91852119262363 0.8557738010456931 0.663554125657286 0.78813539053521 0.7605131382720484 1.0 13.655495062383322 -4.759038104469462 24.991846588346316 0.8063802163764084 1.1386252916924153 0.5276227215136153 0.09145584006299373 48.57947512861481 505492.47786174045 0.02189421776862049 0.14344181587165053 1.7416540560797964e-05 4.759038104469462 0.3322450753160069 RPMEEDGEEKS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 2 RPMEEDGEEKSPSK 14 2 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 RPMEEDGEEKS(1)PSK;RPMEEDGEEKS(0.992)PS(0.008)K 144.88 0.00045575 13034800.0 140829.0 139976.0 117565.0 115732.0 124647.0 130040.0 148896.0 120220.0 133284.0 133966.0 True False 185609.69257482866 185220.5046201299 116006.01128439361 89051.77544157585 107341.91561383489 121908.57824288933 162147.4555502278 101642.76138077145 140329.12013532093 129275.89111607673 1.4357641705070117 1.4327536481943146 0.8973522462918619 0.6888506021715707 0.8303320494418612 0.943010929496728 1.2542745143766654 0.786246843887593 1.085501085498761 1.0 16.980093723983032 -5.25923499523205 24.326408459851354 0.9271221236056485 1.434258995973161 0.6387884473639569 0.14985142318737385 80.57616000698133 889172.0341422354 0.040492423971544754 0.09688237187722483 5.5050973689835296e-06 5.25923499523205 0.5071368723675126 RPMEEDGEEKS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPMEEDGEEKSPSK 14 2 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 RPMEEDGEEKS(0.983)PS(0.017)K 102.15 0.004319600000000001 3153400.0 25587.0 25779.0 15637.0 25007.0 22816.0 19338.0 29767.0 25316.0 20879.0 19735.0 True False 29918.37373371415 28338.16875252423 16009.845383652737 23605.938863787887 18345.36858602644 18323.8812373966 26947.254265582716 24651.481824519222 21184.315875812714 23312.799277825954 1.2833454008318559 1.2155626793166008 0.6867405836964656 1.0125741907897243 0.7869225985004598 0.7860009010082895 1.1558995530499714 1.0574226428469515 0.9086989350078712 1.0 14.508834625619263 -5.098642700312771 7.642852906552963 0.9282185975009151 1.2667378630241362 0.48707822516922217 0.13418413727674697 0.2136656659727101 14.366472944318094 0.03534383548732912 0.0950856368816188 7.9681463052882e-06 5.098642700312771 0.3385192655232211 RPMEEDGEEKS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 6 RPMEEDGEEKSPSK 14 2 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 RPMEEDGEEKS(0.991)PS(0.009)K;RPMEEDGEEKS(0.927)PS(0.073)K;RPMEEDGEEKS(0.719)PS(0.281)K;RPMEEDGEEKS(0.954)PS(0.046)K;RPMEEDGEEKS(0.96)PS(0.04)K;RPMEEDGEEKS(1)PSK 164.7 0.00011328 245542300.0 278448.0 295466.0 249975.0 301785.0 311703.0 281352.0 302508.0 283410.0 257601.0 273651.0 True False 274477.28045889066 294781.8666303772 229423.02043140412 323979.2756252475 293369.2423716768 269319.2308235454 318170.3840569883 296578.2632390713 228587.2627212126 320951.2107329622 0.85519939255584 0.9184631706394826 0.7148221061620754 1.0094346579511886 0.914061803043846 0.8391282594276437 0.9913356716442251 0.9240602724687347 0.7122181038020815 1.0 18.291994477755303 -5.773614501969142 24.99969919770093 0.9099708997367455 0.8383916755513637 0.13597047520901007 0.09535303926715111 506.50134770012323 1040020.4100128135 0.02645974086258833 0.039577276909700865 1.6841683363644023e-06 5.773614501969142 -0.07157922418538176 RPMEFEAALLSPGS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 RPMEFEAALLSPGSPK 16 1 Q9H9L7-2;Q9H9L7;B4DQP0 Q9H9L7-2 AKIRIN1 Akirin-1 1 RPMEFEAALLS(0.036)PGS(0.964)PK;RPMEFEAALLS(0.002)PGS(0.998)PK;RPMEFEAALLS(0.001)PGS(0.999)PK;RPMEFEAALLSPGS(1)PK 124.2 0.0002316 16582900.0 195525.0 180222.0 170948.0 243756.0 206284.0 196189.0 209142.0 186306.0 195203.0 208571.0 True False 257697.88282735323 238475.23706670458 168681.11782456093 187561.82019265852 177645.02732102986 183921.27081585876 227755.23283826106 157516.68858597582 205521.03206517705 201268.99277407114 1.2803655410380315 1.184858302214481 0.8380879513513002 0.9318962529076735 0.8826249134184335 0.9138082735988768 1.131596227015064 0.782617761508807 1.0211261517857295 1.0 17.618765404188714 -5.121502014606643 4.62377684945314 0.9345103164814793 1.2594384702830024 0.6191702599297348 0.09353846528598371 0.12918269798126997 4.1999286432230365 0.023104808146947153 0.06805613983542397 7.559585535878127e-06 5.121502014606643 0.32492815380152307 RPMEFEAALLSPGS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPMEFEAALLSPGSPK 16 1 Q9H9L7-2;Q9H9L7;B4DQP0 Q9H9L7-2 AKIRIN1 Akirin-1 1 RPMEFEAALLS(0.001)PGS(0.999)PK;RPMEFEAALLS(0.002)PGS(0.998)PK 112.14 0.00014138 13544900.0 164879.0 175670.0 151927.0 173633.0 180091.0 165049.0 184838.0 195545.0 155268.0 141716.0 True False 192789.75819131068 193109.35663741577 155549.51586635606 163904.90593578087 144803.46134406058 156393.53988784124 167328.8065287658 190412.15094705368 157538.50076180283 167407.98897676132 1.1516162362960631 1.1535253354260302 0.9291642341390804 0.9790745766531684 0.8649734234855507 0.9342059530357953 0.9995270091440707 1.1374137644857898 0.9410452973285014 1.0 17.35300885168074 -5.252525992681595 24.431343207063104 0.9739788390904307 1.1525708278489197 0.5356949561109396 0.06680240101166453 388.66260424010244 1065304.65928305 0.018531220228477044 0.04741414759528738 5.59080065425372e-06 5.252525992681595 0.17859198875848903 RPMEFEAALLSPGS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 RPMEFEAALLSPGSPK 16 1 Q9H9L7-2;Q9H9L7;B4DQP0 Q9H9L7-2 AKIRIN1 Akirin-1 1 RPMEFEAALLS(0.123)PGS(0.877)PK;RPMEFEAALLS(0.001)PGS(0.999)PK;RPMEFEAALLSPGS(1)PK 122.49 2.6306999999999997e-05 9984200.0 133414.0 117832.0 99371.0 119931.0 105922.0 100828.0 105741.0 101744.0 106391.0 91736.0 True False 131511.49189486913 117559.16724357633 91201.09996315297 128751.12581808805 99691.87621066427 96515.82148154789 111215.75158531326 106471.39767473296 94408.12523310269 107592.44536946334 1.2223115799930917 1.092634030576107 0.8476533798444317 1.1966558188724832 0.9265694804902966 0.8970501706706333 1.033676214007478 0.9895806095782952 0.8774605401793145 1.0 16.71521725669342 -4.980505810610917 4.497515464546863 0.9759125560372904 1.2051625886247659 0.4163149129228447 0.09401677158618413 0.1810467279704518 9.132212403844218 0.023176249180448385 0.09495640390841356 1.0459096966980824e-05 4.980505810610917 0.22925003258747545 RPMSDPS(ph)WNR ddPTM_PC-9_Lapatinib_30min_R1 1 RPMSDPSWNR 10 1 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 RPMS(0.12)DPS(0.88)WNR 84.821 0.012519 0.0 15863.0 16455.0 21033.0 16080.0 15740.0 17536.0 20787.0 17725.0 17629.0 10682.0 True False 15636.790711082072 16416.899458492182 19303.7479297279 17262.576841307524 14814.204146030635 16786.02615841258 21863.249148427865 18548.56820829382 15643.436378400138 12528.369467129693 1.2481105982791976 1.310377978679884 1.54080289381428 1.3778789719283766 1.182452687470482 1.3398412460977922 1.7450993288304448 1.4805253195125783 1.2486410477790708 1.0 13.612911043630127 -5.010139378121835 23.23895405305698 1.390756760696709 1.263677214511305 0.020213396460806998 0.1937549347486227 601.0314741769207 1377601.5704183076 0.049054247218409286 0.15389821227550468 9.76923646548942e-06 5.010139378121835 -0.12707954618540396 RPNEDS(ph)DEDEEKGAVVPPVHDIYR ddPTM_PC-9_AZD4547_30min_R2 2 RPNEDSDEDEEKGAVVPPVHDIYR 24 2 H0YE74;E9PLP8;Q12996 H0YE74 CSTF3 Cleavage stimulation factor subunit 3 1 RPNEDS(1)DEDEEKGAVVPPVHDIYR;RPNEDS(1)DEDEEKGAVVPPVHDIYR 46.982 0.0142 16926900.0 32561.0 31009.0 48204.0 62904.0 44895.0 44265.0 36572.0 49765.0 41751.0 46888.0 True False 42914.72068912646 41032.05283595482 47564.783464065935 48402.45465711199 38662.10419410919 41497.10255245702 39826.83715064824 42074.96273593481 43957.87262364417 45246.46539159649 0.9484657048392757 0.9068565352195577 1.0512375508761844 1.069751067585086 0.8544778881510113 0.917134679876324 0.8802198537710568 0.9299060682815079 0.9715205871486341 1.0 15.465517474260462 -6.2677114608491475 24.969809405739277 0.919351895144764 0.991930475692864 0.24604331284451397 0.05812236315064212 741.6621598987831 2952627.5894795917 0.018828042324679942 0.021886282823086443 5.398691848899647e-07 6.2677114608491475 0.07257858054809996 RPNEDS(ph)DEDEEKGAVVPPVHDIYR ddPTM_PC-9_Lapatinib_30min_R1 3 RPNEDSDEDEEKGAVVPPVHDIYR 24 2 H0YE74;E9PLP8;Q12996 H0YE74 CSTF3 Cleavage stimulation factor subunit 3 1 RPNEDS(1)DEDEEKGAVVPPVHDIYR;RPNEDS(1)DEDEEKGAVVPPVHDIYR;RPNEDS(1)DEDEEKGAVVPPVHDIYR 71.001 0.00021243 69375000.0 162725.0 136752.0 121188.0 121570.0 125590.0 112132.0 111272.0 100928.0 135829.0 108828.0 True False 160404.51165988954 136435.3591460178 111224.39043920835 130510.6633456313 118203.04311944013 107336.37575245877 117033.1197019225 105617.48333577848 120530.50767722017 127638.77479580513 1.256706764198439 1.0689178062409745 0.8713997029283906 1.0225001262697841 0.926074723833254 0.8409386248353928 0.9169088303233134 0.8274717734069759 0.9443095005420048 1.0 16.961707139808013 -4.886791955421666 2.136839736683908 0.9125671322881931 1.3108191983339532 0.7533231675820204 0.060356973700215644 0.24446355409552706 1.5366453810804943 0.016130732457222057 0.17476618215800635 1.2978008210510242e-05 4.886791955421666 0.39825206604576013 RPNPDILDHER ddPTM_PC-9_AZD4547_30min_R2 2 RPNPDILDHER 11 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L0N7 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 ; 121.68 0.00029521 5352300.0 31022.0 23168.9 37647.0 53340.0 49310.0 37026.0 29888.0 43857.0 32729.0 36913.0 False True 40886.35070231503 30657.793832466505 37147.7761818872 41043.287094784995 42464.15765255649 34710.75836681967 32547.97409927196 37079.9083836008 34458.988122422204 35620.687105442754 1.1478259973280442 0.8606738478040775 1.0428708483899827 1.152231762775673 1.1921206777077602 0.9744550481036608 0.913737963642445 1.0409655567237803 0.9673869574839548 1.0 15.120427725131432 RPNPDILDHER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPNPDILDHER 11 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L0N7 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 ; 110.08 0.00078619 6650900.0 20505.5 18381.8 23983.0 25566.0 23512.0 24804.0 25270.0 23724.0 21165.0 18429.300000000003 False True 23976.676147914022 20206.62362291594 24554.84567603399 24133.619906090342 18904.992382304234 23503.23457505354 22876.24266104329 23101.27013765578 21474.498084753865 21770.386203741487 1.101343629071374 0.9281701956873509 1.1279012437461473 1.1085526770279668 0.8683811212800256 1.0795965838683304 1.0507963637830067 1.0611327663854473 0.9864086876448351 1.0 14.41007938051978 RPNPDILDHER ddPTM_PC-9_Lapatinib_30min_R1 1 RPNPDILDHER 11 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L0N7 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 110.93 0.00074398 3423700.0 33265.0 32370.0 36868.0 29104.0 36545.0 37415.0 33167.0 32396.0 36656.0 30067.0 False True 32790.63499994613 32295.049253806883 33836.85535459558 31244.405248097868 34395.49495023441 35814.84766862491 34884.22497262263 33901.23642741251 32527.415275207644 35264.04088824083 0.9298603952923761 0.9158068230511839 0.9595285878278017 0.8860131868357902 0.9753702095355712 1.0156195026579542 0.9892293705981706 0.9613542740281145 0.922396142242855 1.0 15.105910181360066 -6.367244182665593 9.067918840668785 0.978110437400112 0.9249801687850279 0.46415631352987796 0.02866542531977318 0.3438959932566691 27.04983866260148 0.009187196832310852 0.010415736974452609 4.29294987203516e-07 6.367244182665593 -0.053130268615084186 RPNT(ph)SPDR ddPTM_PC-9_Lapatinib_30min_R1 1 RPNTSPDR 8 1 E7ERS3;Q86VM9;H3BRH3 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 RPNT(0.5)S(0.5)PDR 89.82700000000001 0.03387 145830000.0 18389.0 55327.0 49432.0 55327.0 63435.0 47053.0 67474.0 68568.0 72433.0 56240.0 True False 18126.76948787041 55198.89373078077 45367.89177303805 59395.93214546153 59703.87801800844 45040.65287590027 70967.47356718246 71753.91959979082 64274.83278669567 65961.00906491051 0.2748103727466074 0.8368412568773922 0.6877986315884387 0.9004703382722896 0.905138942905731 0.6828375356049653 1.0759003625512342 1.0878232552382523 0.9744367725400392 1.0 16.00932584869789 -4.61582018039072 0.5699585548669921 0.9889576272528326 4.5613871261500223e-38 0.6526513037517785 0.1364327545695445 3.2192087213558063 0.6945129050406499 0.07391599205770027 2.196701370019471 2.4220316812522395e-05 4.61582018039072 -0.9889576272528326 RPNT(ph)SPDRGSR ddPTM_PC-9_AZD4547_30min_R2 1 RPNTSPDRGSR 11 2 E7ERS3;Q86VM9;H3BRH3 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 RPNT(0.462)S(0.462)PDRGS(0.076)R 112.02 0.0073216999999999996 818310.0 1227.7 463.76 2314.5 6857.6 4378.0 2297.1 874.25 2791.5 1273.1 3534.0 True False 1618.0830622536316 613.6613506789125 2283.8082177325637 5276.686268863843 3770.190269780823 2153.461973867593 952.0565563533363 2360.1378172884956 1340.3934669148373 3410.2757356658813 0.47447279565436346 0.1799447898775524 0.669684328996533 1.547290212834808 1.1055382502801245 0.6314627146848915 0.27917289689991603 0.6920665659393261 0.39304548101390274 1.0 11.735672676813381 -5.424997407461058 6.125520099530864 0.8007482682667892 0.33876047395872366 0.22683801064730869 0.3484724730901542 0.38039953425269585 19.68048177740576 0.10236010440016415 0.21550420054111447 3.7583964787213066e-06 5.424997407461058 -0.4619877943080656 RPNTS(ph)PDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPNTSPDR 8 1 E7ERS3;Q86VM9;H3BRH3 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 RPNT(0.019)S(0.981)PDR 77.192 0.035095 6887500.0 5308.4 5642.8 6470.5 5398.5 8434.8 5996.1 4158.0 6330.2 6158.5 6069.5 True False 6207.007274320874 6202.9798920339745 6624.781259507903 5096.0395471731445 6782.061489718435 5681.653960469221 3764.1241386869015 6164.0389574013125 6248.556411762664 7169.852303864433 0.8657092240206117 0.8651475133861083 0.9239773678374454 0.7107593477799343 0.945913695608906 0.7924366806561555 0.5249932605526755 0.8597163088114097 0.8715042021709142 1.0 12.807727684945332 -5.736637390911435 24.988845454112624 0.8016262111348438 0.8829649703777999 0.054609829011573185 0.1247368143743195 646.5062595361594 651371.6091554678 0.03431607439225353 0.05940513067188044 1.8338449306780288e-06 5.736637390911435 0.08133875924295608 RPPES(ph)PPIVEEWNSR ddPTM_PC-9_AZD4547_30min_R2 4 RPPESPPIVEEWNSR 15 1 A0A3B3IU46;Q9BTL3 A0A3B3IU46 FAM103A1 RNMT-activating mini protein 1 RPPES(1)PPIVEEWNSR;RPPES(1)PPIVEEWNSR;RPPES(1)PPIVEEWNSR;RPPES(1)PPIVEEWNSR 122.13 2.5177e-05 46231000.0 27146.300000000003 42100.100000000006 48385.1 55701.0 50236.5 55007.7 40120.2 53302.6 38521.3 48277.0 True False 35778.258721883 55708.13401267315 47743.48195973727 42859.99502187134 43262.0291201106 51568.05982321898 43690.82007687403 45065.9079418957 40557.45727520741 46586.836924375144 0.7679907262208462 1.195791294075292 1.0248277219859274 0.9200022549598372 0.9286320337725067 1.1069233978458315 0.9378361563331237 0.9673528171713314 0.8705776127502435 1.0 15.507634759610932 RPPES(ph)PPIVEEWNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RPPESPPIVEEWNSR 15 1 A0A3B3IU46;Q9BTL3 A0A3B3IU46 FAM103A1 RNMT-activating mini protein 1 RPPES(1)PPIVEEWNSR;RPPES(1)PPIVEEWNSR;RPPES(1)PPIVEEWNSR;RPPES(1)PPIVEEWNSR 131.13 4.7622e-06 38179300.0 50011.600000000006 37511.7 46733.3 56053.0 70319.0 44769.9 58947.8 48596.4 45565.600000000006 41631.8 True False 58477.57610587486 41235.61366981124 47847.59910902723 52912.53213627795 56540.49673916515 42422.08763109535 53363.83763888596 47320.79599214194 46231.91069835393 49179.31578285251 1.1890685174246447 0.8384747329931129 0.9729212037087833 1.0759102946838295 1.149680426397459 0.8626002000191875 1.0850870287522887 0.9622093198913804 0.9400681966070326 1.0 15.585764042837404 -6.765162222816143 24.999992106206758 0.9748244446455373 1.031415086601531 0.10780097328821836 0.10402967215330286 310.7765402001344 2086943.78198005 0.036283891208316675 0.03320112534808265 1.7172668135114333e-07 6.765162222816143 0.056590641955993726 RPPES(ph)PPIVEEWNSR ddPTM_PC-9_Lapatinib_30min_R1 3 RPPESPPIVEEWNSR 15 1 A0A3B3IU46;Q9BTL3 A0A3B3IU46 FAM103A1 RNMT-activating mini protein 1 RPPES(1)PPIVEEWNSR;RPPES(1)PPIVEEWNSR;RPPES(1)PPIVEEWNSR 124.73 1.303e-05 34701700.0 22811.4 17617.7 27573.9 19840.1 22515.4 18903.9 18868.7 13675.3 19831.1 20886.0 True False 22486.105252901576 17576.907298078262 25306.880380332055 21299.207138633403 21191.08843897955 18095.424264143214 19845.62896074183 14310.704362137121 17597.51268725912 24496.117271154362 0.9179456892697156 0.7175385022660762 1.0330976170714374 0.869493189588641 0.8650794819607318 0.7387058146333931 0.8101540640528873 0.5842029658712007 0.7183796718666611 1.0 14.580265474182832 -6.720031788219998 4.785453850695134 0.7462848520039989 0.8811759727059066 0.15847951786195835 0.12125562499611174 0.3109234716597598 15.947654258566187 0.04039595446845577 0.03919649800769776 1.9053212527148468e-07 6.720031788219998 0.13489112070190779 RPPGADAEGSER ddPTM_PC-9_Lapatinib_30min_R1 1 RPPGADAEGSER 12 1 E7EPJ7;O75962-4;O75962;O75962-5 E7EPJ7 TRIO Triple functional domain protein 0 80.17 0.0092295 873420.0 2981.5 3322.7 3772.0 3300.6 3835.6 3959.8 3627.2 2388.0 2150.7 2591.5 False True 2938.983263259864 3315.006492296078 3461.8807203410656 3543.337134478829 3609.997549079742 3790.4485847446444 3814.9986679740923 2498.955197822603 1908.4655181249746 3039.437322043306 0.9669497844042034 1.0906645346012651 1.1389873695483104 1.1657872030395313 1.187719030393714 1.247088912561112 1.2551660928508321 0.8221769140291547 0.6279009289923376 1.0 11.569588553122692 -7.8060634885121605 8.129288275475638 0.7910375769987422 1.1532331708143349 0.6398825649037809 0.11423165793429009 0.15375776028144125 24.455654106041433 0.06290428606603418 0.03034122970461102 1.5629191463817727e-08 7.8060634885121605 0.36219559381559263 RPPGGT(ph)SPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLR 45 1 H3BUF6;Q8WWM7-7;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 RPPGGT(0.487)S(0.487)PPNGGLPGPLAT(0.013)S(0.013)AAPPGPPAAASPCLGPVAAAGSGLR;RPPGGT(0.467)S(0.467)PPNGGLPGPLAT(0.033)S(0.033)AAPPGPPAAASPCLGPVAAAGSGLR 44.317 0.004012699999999999 20798000.0 11955.0 13902.4 16683.1 17608.9 16300.2 17394.7 16233.9 16175.3 13427.7 11896.599999999999 True False 13978.745377986974 15282.538394239233 17080.888375009086 16622.330421824066 13106.292821964773 16482.491310380745 14696.107468742013 15750.715514147014 13624.054709787362 14053.359406566206 0.9946906624657753 1.0874651357097374 1.2154309785195074 1.1828012036792819 0.9326092390294287 1.172850621231502 1.0457362573304354 1.1207793850904963 0.9694518097517483 1.0 13.778627422441623 -8.264265368991216 24.915515936024054 0.9847258909138802 1.0964661303589067 0.21815469791690323 0.0826804499359016 372.8619480152139 3287258.140775735 0.06891651972806521 0.02092176828416381 5.441700444643523e-09 8.264265368991216 0.11174023944502653 RPPGGT(ph)SPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLR ddPTM_PC-9_Lapatinib_30min_R1 2 RPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLR 45 1 H3BUF6;Q8WWM7-7;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 RPPGGT(0.385)S(0.385)PPNGGLPGPLAT(0.115)S(0.115)AAPPGPPAAASPCLGPVAAAGSGLR;RPPGGT(0.494)S(0.494)PPNGGLPGPLAT(0.006)S(0.006)AAPPGPPAAASPCLGPVAAAGSGLR 53.687 0.00022181 22219000.0 28842.1 28922.9 33809.5 26971.1 31844.4 32290.8 28011.3 30914.6 32690.4 26598.4 True False 28430.80636500665 28855.930802067665 31029.81341844413 28954.644666952066 29971.375000499236 30909.797757531305 29461.588053656484 32351.00517529591 29008.46290682695 31195.89799985982 0.9113636147013433 0.924991189617216 0.994676076277194 0.9281555115702127 0.960747307246418 0.9908289146755833 0.9444058335422456 1.0370275340508321 0.9298806819716265 1.0 14.929068718754843 -1.522878745280338 0.3463388155413952 0.9843225503512001 0.14334552878631052 0.30242522116693615 0.032769014952485936 73.99569381592394 1.0443641492201785 0.026643450160861518 40.49186403128916 0.029999999999999964 1.522878745280338 -0.8409770215648895 RPPGGTS(ph)PPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRR ddPTM_PC-9_AZD4547_30min_R2 1 RPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRR 46 2 H3BUF6;Q8WWM7-7;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 RPPGGT(0.264)S(0.734)PPNGGLPGPLAT(0.001)S(0.001)AAPPGPPAAASPCLGPVAAAGSGLRR 47.238 0.00024265 11469000.0 6917.8 1092.8 5151.7 16721.0 15536.0 8425.4 5413.8 7120.5 6796.9 10828.0 True False 9117.516500821192 1446.0262291312656 5083.385091939016 12866.231786874754 13379.094570880501 7898.558406087678 5895.617712079721 6020.1903378121915 7156.170257853638 10448.915015786695 0.872580214026627 0.13839008422851018 0.4864988455029835 1.231346198857572 1.2804290733216566 0.7559213941499359 0.5642325258816207 0.5761545891335718 0.6848720893070497 1.0 13.351065524476729 -4.461709122517143 23.228723991311806 0.7370320007028873 4.445294338279944 0.012273537912324328 0.3299601105141353 4290.007535630477 1617841.457884946 0.08790312269659097 5667.059069804096 3.45374983743621e-05 4.461709122517143 3.708262337577057 RPPGPTTS(ph)PASTSLSSPGQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPPGPTTSPASTSLSSPGQR 20 1 Q01970-2;Q01970 Q01970-2 PLCB3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1 RPPGPT(0.107)T(0.107)S(0.693)PAS(0.043)T(0.043)S(0.005)LS(0.001)SPGQR;RPPGPT(0.272)T(0.178)S(0.375)PAS(0.018)T(0.018)S(0.005)LS(0.128)S(0.007)PGQR 63.43600000000001 0.012067 8860400.0 15253.400000000001 22473.0 22672.0 17835.9 24782.0 17770.7 23441.0 19447.7 16366.400000000001 15180.400000000001 True False 17835.49935161745 24703.97092111708 23212.586464038795 16836.612347768005 19926.14499907552 16838.773208470564 21220.498781856586 18937.21848154142 16605.727637813165 17932.486352019714 0.9945915475133575 1.377609910648821 1.2944432806677915 0.938888897906325 1.111175807298538 0.9390093976886832 1.1833550777785227 1.056028601377329 0.9260136777376039 1.0 14.130287912320371 -5.755351590587772 24.999997325395636 1.0313742993301107 1.2377544389721966 0.3697131874220566 0.11880477216349304 148.55889955132113 610060.9321941726 0.03154447076180545 0.0528821862701595 1.7565010324948152e-06 5.755351590587772 0.2063801396420859 RPPGPTTSPASTSLSS(ph)PGQR ddPTM_PC-9_AZD4547_30min_R2 2 RPPGPTTSPASTSLSSPGQR 20 1 Q01970-2;Q01970 Q01970-2 PLCB3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1 RPPGPTTSPAS(0.008)T(0.018)S(0.018)LS(0.284)S(0.671)PGQR;RPPGPTTSPAS(0.001)T(0.005)S(0.005)LS(0.1)S(0.888)PGQR 66.711 0.015987 5247100.0 25521.0 22004.9 30349.0 40427.0 35881.0 27944.1 27778.0 31972.0 24150.0 31023.0 True False 33636.14713022315 29117.5535957271 29946.552430315664 31107.179740923733 30899.542501143365 26196.751009513453 30250.18818688358 27031.46204347047 25426.519696797834 29936.894212666284 1.1235683598732067 0.9726310748496909 1.0003226192263222 1.039091748126708 1.0321559170980998 0.8750657574368427 1.010465146183559 0.9029481098287568 0.8493372597762625 1.0 14.869636937071347 -6.7435566272916585 24.879309556051606 0.9266788834348592 1.0286308455831605 0.4463794997616325 0.05888738408500851 224.85361614221586 312826.07519475283 0.01907924550179499 0.019040171554967917 1.8048593876931937e-07 6.7435566272916585 0.10195196214830138 RPPS(ph)PDVIVLS(ph)DNEQPSSPR ddPTM_PC-9_AZD4547_30min_R2 1 RPPSPDVIVLSDNEQPSSPR 20 1 Q86YP4-2;Q86YP4;Q86YP4-3;C9JMI3;C9JGN4;C9JHD7;C9JJK9 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 2 RPPS(1)PDVIVLS(0.649)DNEQPS(0.162)S(0.189)PR 118.15 0.00013603 0.0 5461.1 3597.6 7913.9 7857.4 6246.0 6027.5 6440.7 8782.9 6134.9 6551.7 True False 7197.61620206346 4760.453845097586 7808.956515149596 6045.997825619861 5378.850713807906 5650.599472154853 7013.909822710821 7425.704615963866 6459.178289353418 6322.326977182276 1.1384441564063619 0.7529591339199 1.235139616051601 0.9562931255280364 0.8507707262247836 0.8937531216826123 1.1093873898051327 1.1745208121572575 1.0216457188413457 1.0 12.62623993492518 -7.278800419638637 23.862820713654155 1.0909319009750005 0.9671473724788644 0.12068918446056554 0.13655914269368116 883.5365141054604 1214417.2363506546 0.055937481661624835 0.03783298112726532 5.262590535803304e-08 7.278800419638637 -0.12378452849613608 RPPS(ph)PDVIVLS(ph)DNEQPSSPR ddPTM_PC-9_Lapatinib_30min_R1 1 RPPSPDVIVLSDNEQPSSPR 20 1 Q86YP4-2;Q86YP4;Q86YP4-3;C9JMI3;C9JGN4;C9JHD7;C9JJK9 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 2 RPPS(1)PDVIVLS(0.535)DNEQPS(0.251)S(0.214)PR 79.395 0.0064203 0.0 7977.2 4660.6 6059.2 6809.7 5777.7 3526.5 6134.8 6149.0 5442.4 5811.9 True False 7863.443665160686 4649.808667046411 5561.035965188389 7310.508054493267 5437.867045395248 3375.679815673014 6452.429926193061 6434.70498802813 4829.419600987289 6816.479171130041 1.153593147979513 0.6821422834738248 0.8158223366604194 1.0724756682974395 0.7977530494667021 0.49522337425603713 0.9465927738063303 0.9439924668560793 0.7084918004945161 1.0 12.734811039462157 -4.744717914481825 24.717056661837088 0.8268544148996928 1.1535942494225995 0.2637707031134584 0.16256287728606253 1263.565090221593 1867639.5510419714 0.04103388660215754 1.1132456954029541 1.8000397079348027e-05 4.744717914481825 0.32673983452290667 RPPS(ph)PDVIVLSDNEQPS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 RPPSPDVIVLSDNEQPSSPR 20 1 Q86YP4-2;Q86YP4;Q86YP4-3;C9JMI3;C9JGN4;C9JHD7;C9JJK9 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 2 RPPS(1)PDVIVLS(0.007)DNEQPS(0.541)S(0.452)PR 86.70100000000001 0.0013755 0.0 4949.1 4949.0 8233.5 9015.4 8285.3 7861.8 6132.9 7464.0 7225.1 7043.9 True False 6522.810852325044 6548.667467030228 8124.318410326671 6937.038816541517 7135.029109688228 7370.2004031832475 6678.71621899843 6310.61030565694 7607.004035666013 6797.295204996299 0.9596185917496275 0.9634225481654352 1.1952281260868227 1.0205587086231742 1.0496865141951877 1.0842842896930296 0.9825549748213512 0.9284002114574008 1.1191222105631875 1.0 12.730745064757347 -7.2758509156176325 24.384349051926645 1.0015527019144215 1.0476041944521073 0.05341102923839958 0.07631465640699586 1733.1764384603239 2932524.113709228 0.03228058050580215 0.021881570958079792 5.2984529769291806e-08 7.2758509156176325 0.04605149253768581 RPPS(ph)PDVIVLSDNEQPS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPPSPDVIVLSDNEQPSSPR 20 1 Q86YP4-2;Q86YP4;Q86YP4-3;C9JMI3;C9JGN4;C9JHD7;C9JJK9 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 2 RPPS(1)PDVIVLSDNEQPS(0.794)S(0.206)PR 151.28 5.6652e-05 3070400.0 7384.7 7178.2 8096.1 7932.1 8997.6 7895.3 6871.2 6712.4 7342.1 6645.3 True False 8634.783855526595 7890.8042569288755 8289.14172863023 7487.6901532151705 7234.5848698120335 7481.256569118697 6220.310192819972 6536.206612375688 7449.464322611454 7850.040285834145 1.0999668206937188 1.0051928359104465 1.0559362024661796 0.9538409843229905 0.9215984385286867 0.9530214236758836 0.792392136387489 0.8326335119796332 0.9489714767520934 1.0 12.938484342491066 -5.969061744254083 1.1057646734110937 0.8867544666349312 1.0662753347600522 0.5233208209518201 0.06109397340919105 0.39795498942555235 0.9856847838904322 0.02406530184539378 0.050701485037149455 1.0738367326175508e-06 5.969061744254083 0.17952086812512102 RPPS(ph)PDVIVLSDNEQPSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 RPPSPDVIVLSDNEQPSSPR 20 1 Q86YP4-2;Q86YP4;Q86YP4-3;C9JMI3;C9JGN4;C9JHD7;C9JJK9 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 2 RPPS(1)PDVIVLS(0.036)DNEQPS(0.446)S(0.517)PR 76.79899999999999 0.008424700000000002 0.0 6004.4 5586.1 4582.7 6780.0 5648.6 5398.9 4055.0 6526.8 6429.4 5696.4 True False 5918.776154927896 5573.1657286589625 4205.928095733563 7278.623817416973 5316.360453574885 5168.001632450599 4264.948058732617 6830.058955254844 5705.253267416523 6681.015150024113 0.8859097041422715 0.8341794777458106 0.629534285028284 1.0894487819550451 0.7957414156673027 0.7735353859258868 0.6383682663430608 1.0223085566914472 0.8539500568855816 1.0 12.705851615001219 -7.79282408076182 24.997546940189764 0.9535969702833132 0.8100994675545183 0.22703542813407063 0.12837668195518412 335.83821452954277 267486.78953411017 0.0698815606506829 0.03357513857010683 1.6112981899758195e-08 7.79282408076182 -0.1434975027287949 RPPS(ph)PDVIVLSDNEQPSSPR ddPTM_PC-9_AZD4547_30min_R2 3 RPPSPDVIVLSDNEQPSSPR 20 1 Q86YP4-2;Q86YP4;Q86YP4-3;C9JMI3;C9JGN4;C9JHD7;C9JJK9 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 1 RPPS(1)PDVIVLSDNEQPSSPR;RPPS(1)PDVIVLSDNEQPSSPR;RPPS(1)PDVIVLSDNEQPSSPR 132.13 9.3079e-07 16506900.0 35003.0 35080.9 49140.6 67698.0 55549.0 54670.9 47186.9 59445.0 40791.5 47516.6 True False 46133.225892370996 46420.11488061038 48488.96353610235 52091.27202367371 47836.980195535594 51252.31998046137 51386.44268686218 50259.14116020587 42947.65541250223 45853.05829692742 1.0061101179692162 1.0123668214235768 1.0574859199599247 1.1360479313364429 1.043266948210107 1.1177513972693016 1.1206764520286219 1.0960913628649651 0.9366366608392646 1.0 15.48473034112694 -1.5631075128670195 15.487243103840342 1.060082990799922 0.005297194535627492 0.0 0.061961986531247 0.0 0.0 0.014363379586697181 0.0 0.02734591673759064 1.5631075128670195 -1.0547857962642946 RPPS(ph)PDVIVLSDNEQPSSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RPPSPDVIVLSDNEQPSSPR 20 1 Q86YP4-2;Q86YP4;Q86YP4-3;C9JMI3;C9JGN4;C9JHD7;C9JJK9 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 1 RPPS(1)PDVIVLSDNEQPSSPR;RPPS(1)PDVIVLSDNEQPSSPR;RPPS(1)PDVIVLSDNEQPSSPR 112.91 1.5481e-05 18385500.0 30210.0 33021.5 36821.0 41356.0 43765.0 35915.0 34251.8 39357.0 32517.4 26879.5 True False 35323.956325302104 36299.65628850923 37698.95228442013 39038.95739796102 35189.56241968123 34031.55417525591 31007.221542442534 38323.920452188446 32992.9054581231 31752.540571995058 1.1124765353880675 1.1432047840771713 1.1872735726120025 1.2294750811968853 1.108243995150345 1.0717742127781384 0.9765272631378077 1.2069560344405694 1.039063484804174 1.0 14.954584408410073 -6.506669767388841 4.962509306009921 1.0682690627675 1.168329032926979 0.3876640164864902 0.06410134349139888 0.21845635959708185 15.077828694297763 0.020939538414855127 0.022509977267892452 3.114083350819184e-07 6.506669767388841 0.1000599701594791 RPPS(ph)PDVIVLSDNEQPSSPR ddPTM_PC-9_Lapatinib_30min_R1 3 RPPSPDVIVLSDNEQPSSPR 20 1 Q86YP4-2;Q86YP4;Q86YP4-3;C9JMI3;C9JGN4;C9JHD7;C9JJK9 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 1 RPPS(1)PDVIVLSDNEQPSSPR;RPPS(1)PDVIVLSDNEQPSSPR;RPPS(1)PDVIVLSDNEQPSSPR 123.42 3.1607e-06 18261900.0 46192.0 39873.5 45477.0 40617.3 52228.0 44005.9 36910.3 33256.8 50673.0 37266.5 True False 45533.29360942467 39781.17536057053 41738.05660629656 43604.431737340776 49156.05172419874 42123.870239763244 38821.33473051507 34802.03233791739 44965.67312965402 43707.9648705101 1.0417619247275025 0.9101584912138294 0.9549302222135114 0.9976312524850779 1.124647461162496 0.9637573006329643 0.8881981772779346 0.7962400546678949 1.0287752647113637 1.0 15.415608584495812 -7.004810635928715 24.98946393593746 0.91341684781271 1.0019256334663897 0.16612578748799123 0.07903567844073592 338.3583777973405 1757651.9667866165 0.02888555386282763 0.024809125435594506 9.889842243713611e-08 7.004810635928715 0.0885087856536797 RPPS(ph)PEPSTK ddPTM_PC-9_AZD4547_30min_R2 5 RPPSPEPSTK 10 1 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 RPPS(0.999)PEPS(0.001)TK;RPPS(0.999)PEPS(0.001)TK;RPPS(0.999)PEPS(0.001)TK;RPPS(1)PEPSTK;RPPS(0.999)PEPST(0.001)K 91.20200000000001 0.0056637 4179598200.0 652339.0 709259.0 916454.0 1046896.0 1025780.0 917520.0 809412.0 846067.0 802097.0 948413.0 True False 859769.2325058845 938513.1014343075 904301.221159593 805550.3015819655 883368.1532516609 860147.3293557074 881448.0999611855 715326.7858355097 844494.209906521 915209.3495444497 0.9394235678796761 1.0254627554902682 0.988081275185523 0.8801814601030162 0.9652088384929219 0.9398366939584373 0.9631108995990163 0.7815990802449377 0.9227333727817274 1.0 19.803742264831648 -6.01463760345855 0.7815424963544387 0.9068721616139013 0.9910937663564743 0.10230493374526373 0.06238174952019894 1.4458410136968518 1.7652275143956722 0.03265665048745432 0.07863024322579429 9.668573354846669e-07 6.01463760345855 0.08422160474257301 RPPS(ph)PEPSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RPPSPEPSTK 10 1 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 RPPS(0.999)PEPS(0.001)T(0.001)K;RPPS(0.999)PEPSTK;RPPS(0.998)PEPS(0.002)T(0.001)K;RPPS(1)PEPSTK 91.307 0.0061508000000000005 3013270000.0 701451.0 711908.0 646359.0 817221.0 946744.0 811090.0 774082.0 733548.0 709386.0 657787.0 True False 820192.8000112384 782581.5214039357 661770.649890159 771434.7568362312 761236.3094586703 768555.0125576588 700755.3490916379 714293.142258352 719759.4282235397 777038.5760609733 1.0555367845043497 1.0071334236339478 0.8516573954987668 0.9927882354912809 0.9796634722018447 0.9890821848944488 0.9018282626893036 0.9192505549458103 0.9262853227599102 1.0 19.567626697407484 -7.249581205365121 24.48788810464281 0.930111913577002 0.9754012285590066 0.12245503630622112 0.053912653400476546 1212.0353755109554 2502934.8049523267 0.021344978250322295 0.016376667386600572 5.6288385825601877e-08 7.249581205365121 0.045289314982004614 RPPS(ph)PEPSTK ddPTM_PC-9_Lapatinib_30min_R1 3 RPPSPEPSTK 10 1 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 RPPS(0.995)PEPS(0.001)T(0.004)K;RPPS(1)PEPSTK;RPPS(1)PEPSTK 96.23 0.0082431 1110817300.0 168425.0 152521.0 145817.0 129304.0 160795.0 135814.0 129656.0 131607.0 150593.0 133038.0 True False 166023.2286146378 152167.84699536205 133828.48912989759 138813.4475054992 151337.3542351332 130005.55181789714 136368.95326831972 137721.94167497443 133631.6305254077 156033.44103800773 1.0640233754390938 0.9752258617323958 0.8576910708346084 0.8896390836608291 0.9699033311600773 0.833190314544364 0.8739726071611919 0.8826437509727619 0.8564294271563028 1.0 17.25149573461008 -4.9658797118313736 2.997440575355522 0.89093804892731 1.0653234063878536 0.5345624350570037 0.04946875344368481 0.20359491848537678 3.385776243083699 0.012363890308209686 0.0696063272495607 1.0817335215928939e-05 4.9658797118313736 0.17438535746054362 RPPTPAPWPSSGLGTPLT(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPPTPAPWPSSGLGTPLTPPK 21 1 M0R0S1;M0R2P6;Q8TBC3;M0R1G0;M0QZE8;M0R0K4;M0QYB1;M0R0E3;M0R0S2 M0R0S1 SHKBP1 SH3KBP1-binding protein 1 1 RPPTPAPWPS(0.002)S(0.002)GLGT(0.077)PLT(0.92)PPK 54.833999999999996 0.015375999999999999 4260800.0 22382.0 22075.0 20995.0 27372.0 28089.0 24237.0 28122.0 20839.0 21775.0 19713.0 True False 26170.83053534959 24266.46011140745 21495.60042398088 25838.43558122134 22585.16208857366 22965.969053200006 25458.080574351385 20291.998330745617 22093.41818074726 23286.810851977873 1.1238477738194348 1.042068845994271 0.9230804750644996 1.1095738160739492 0.9698692634270863 0.9862221666669047 1.0932403211489603 0.8713944755995693 0.9487524213248268 1.0 14.50722545434619 RPPTPAPWPSSGLGTPLT(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 1 RPPTPAPWPSSGLGTPLTPPK 21 1 M0R0S1;M0R2P6;Q8TBC3;M0R1G0;M0QZE8;M0R0K4;M0QYB1;M0R0E3;M0R0S2 M0R0S1 SHKBP1 SH3KBP1-binding protein 1 1 RPPTPAPWPSSGLGT(0.01)PLT(0.99)PPK 63.108999999999995 0.005220600000000001 3826100.0 45743.0 47634.0 41373.0 40925.0 49066.0 40230.0 43400.0 42065.0 45419.0 38770.0 True False 45090.69643176116 47523.70639962426 37971.47164439846 43934.76102179789 46180.03434746757 38509.456680710406 45647.03964216908 44019.49346583238 40303.43393672677 45471.342842222264 0.9916288724574973 1.0451353188429764 0.8350637845940229 0.9662076876472275 1.0155854536274493 0.8468950832248696 1.003863901722816 0.9680711128011426 0.8863480033253636 1.0 15.472669989376536 RPQHNSSGAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 RPQHNSSGASPR 12 1 Q9BRD0 Q9BRD0 BUD13 BUD13 homolog 1 RPQHNS(0.008)S(0.269)GAS(0.723)PR 52.42 0.044002 574720.0 484.49 426.34 671.61 0.0 598.14 588.88 2316.1 918.98 0.0 506.41 True False 477.5810837554154 425.35283592425145 616.3928182895717 0.0 562.9585811884856 563.6949751463276 2436.0163252356624 961.6791657014304 0.0 593.9422937510905 0.8040866743791111 0.7161517884808326 1.03779916799104 0.0 0.947833799868124 0.9490736407846401 4.101436033205861 1.6191457921406271 0.0 1.0 9.214178958236248 -7.022840926147274 24.995610025253313 1.8450999985183094 0.7084232835764811 0.17116109752370312 0.9968739262439128 1225.4201343737352 1341015.9193269664 0.38690678774104226 0.3019801520105529 9.487659146703445e-08 7.022840926147274 -1.1366767149418284 RPQS(ph)PGASPSQAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPQSPGASPSQAER 14 1 Q96T58;A0A669KB49 Q96T58 SPEN Msx2-interacting protein 1 RPQS(1)PGASPSQAER;RPQS(0.998)PGAS(0.001)PS(0.001)QAER 69.935 0.013093 9921200.0 4218.4 5052.530000000001 8088.5 6852.400000000001 8114.0 5917.87 6492.360000000001 6398.3 5246.400000000001 5144.33 True False 4932.491802802199 5554.111787392502 8281.360515807073 6468.482243780541 6524.119946836367 5607.526479385263 5877.356660184052 6230.351404559222 5323.118674786329 6076.956306506123 0.8116714279352915 0.9139627647883773 1.3627480761941413 1.0644279664896128 1.0735834878146977 0.9227524761666827 0.9671546681834169 1.025242093297408 0.8759514477810679 1.0 12.56913320356274 -6.753779499871739 24.756542800126855 0.9603561747613621 1.0566844550603507 0.08825713421307957 0.13739999518391974 405.1449568096774 1309415.8403924508 0.04862323724716094 0.04773993081864299 1.7628708645726488e-07 6.753779499871739 0.09632828029898854 RPQS(ph)PGASPSQAER ddPTM_PC-9_Lapatinib_30min_R1 3 RPQSPGASPSQAER 14 1 Q96T58;A0A669KB49 Q96T58 SPEN Msx2-interacting protein 1 RPQS(1)PGASPSQAER;RPQS(1)PGASPSQAER;RPQS(1)PGASPSQAER 127.66 4.126e-05 11219100.0 4956.75 6811.43 9673.210000000001 6392.799999999999 9728.699999999999 8774.96 8461.599999999999 11331.199999999999 12514.8 6166.1 True False 4886.0658360433745 6795.658552328009 8877.916013470414 6862.947837755636 9156.476993360115 8399.67541623084 8899.70024507322 11857.688918579333 11105.251437313633 7231.9021691882035 0.675626650047984 0.9396778874140711 1.2276045507494717 0.9489823945621787 1.266122906414807 1.161475255019071 1.2306167916638493 1.6396362452328892 1.5355920444593378 1.0 12.820159446239625 -4.372413673208004 0.43889631895724185 1.378467276461047 1.7563829457706174e-14 0.5077533329965598 0.1915215727925898 6.06109404346972 0.6949011856170698 0.1414000592150673 4.685841562937069 4.242152988349251e-05 4.372413673208004 -1.3784672764610295 RPQS(ph)PSPR ddPTM_PC-9_AZD4547_30min_R2 1 RPQSPSPR 8 1 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 RPQS(0.97)PS(0.03)PR 76.332 0.01151 7211500.0 2109.7 2393.9 3408.6 5318.4 3886.2 3154.5 2930.9 3054.9 2901.6 2761.8 True False 2780.54071551396 3167.68135973402 3363.3997368603245 4092.3250484608993 3346.6682106948906 2957.2486163272474 3191.7444220943617 2582.835399618352 3054.9726522661967 2665.1102226264957 1.0433117144302222 1.1885742408853301 1.2620114951739807 1.5355181236849063 1.2557335086114045 1.109615876754563 1.1976031591477152 0.9691289229579927 1.1462837920660134 1.0 11.379979485319446 -7.183501830179068 1.5904252395065932 1.0550535010713769 1.2633662243301524 0.30822343464427493 0.12885888454178207 0.5142732984023654 2.55823476307507 0.07482916616796832 0.048196319910541775 6.553875239308854e-08 7.183501830179068 0.2083127232587756 RPQS(ph)PSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPQSPSPR 8 1 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 RPQS(0.969)PS(0.031)PR;RPQS(0.984)PS(0.016)PR 68.786 0.01955 9997600.0 3097.67 3654.09 5588.299999999999 4995.9 4913.700000000001 3883.3 5058.5 5230.799999999999 6088.200000000001 3088.63 True False 3622.0443492286845 4016.843906160494 5721.546265745768 4715.995919926332 3950.8957582905896 3679.6529118410526 4579.322259631476 5093.497042490725 6177.228407257195 3648.574169418372 0.9927287156686972 1.1009352474807519 1.568159505623495 1.2925585998648126 1.0828602009536266 1.008518051430385 1.2550991283155077 1.396023982514433 1.693052716053713 1.0 11.83311706630044 -7.677008973104689 4.1974707722495355 1.4091509942245473 1.1864985449996803 0.11407195146665616 0.222065850981151 0.4178165021935536 13.66989667135139 0.11646277850456094 0.06262424124817767 2.103734973339997e-08 7.677008973104689 -0.22265244922486693 RPQS(ph)PSPR ddPTM_PC-9_Lapatinib_30min_R1 1 RPQSPSPR 8 1 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 RPQS(0.665)PS(0.335)PR 72.321 0.015128 7578900.0 1172.2 2120.6 2710.2 1171.7 2328.6 1195.6 2611.8 1873.2 3378.7 1221.4 True False 1155.4842130448467 2115.6898809892764 2487.377817674539 1257.8707266766176 2191.636326203744 1144.4669750797261 2747.0262243644524 1960.235710452805 2998.155226711701 1432.5173625868006 0.8066109655790175 1.4769034821112546 1.7363683559010414 0.8780841053159657 1.5299195552130322 0.7989201422404256 1.917621591269196 1.3683853066276734 2.092927670557315 1.0 10.484336909693882 -7.275773567305835 24.942193870200793 1.6254323811793487 1.2409861270303937 0.1755423659772274 0.40761630382564906 1405.5695966056353 2445750.9305551136 0.1610762433131846 0.10916375569034788 5.299396721110624e-08 7.275773567305835 -0.38444625414895506 RPQYSNPPVQGEVMEGADNQGAGEQGRPVR ddPTM_PC-9_AZD4547_30min_R2 1 RPQYSNPPVQGEVMEGADNQGAGEQGRPVR 30 2 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 51.586000000000006 0.0090992 11231000.0 5950.3 4843.6 6862.4 15774.0 10245.0 8266.0 6778.0 10555.0 6571.7 8123.2 False True 7842.371626071345 6409.198978239565 6771.400092187496 12137.54800587061 8822.658591572532 7749.125713286109 7381.228869274138 8923.96727977076 6919.066645608548 7838.80924050965 1.0004544549372736 0.8176240525305681 0.8638301921156643 1.5483918071568574 1.1255100514474206 0.9885590369057494 0.9416262907801335 1.138434040932288 0.8826680728307525 1.0 12.936418802104026 RPQYSNPPVQGEVMEGADNQGAGEQGRPVR ddPTM_PC-9_Lapatinib_30min_R1 2 RPQYSNPPVQGEVMEGADNQGAGEQGRPVR 30 2 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 ; 90.09700000000001 5.746899999999999e-09 11692800.0 36101.0 32755.0 37562.0 32039.0 35808.0 36185.0 30989.0 31325.0 33591.0 29725.0 False True 35586.19311988743 32679.15780996122 34473.79735351304 34395.25493897086 33701.843841236645 34637.45190135487 32593.45878965849 32780.47385753476 29807.627851088502 34862.92664392717 1.0207460057311697 0.9373612876431778 0.9888383068240798 0.986585414651705 0.9666957735777821 0.9935325354387144 0.934903117071957 0.9402674133568429 0.8549949967060709 1.0 15.089406064258373 -7.376527148705469 4.240096839980312 0.9255350259584285 0.9799767515496524 0.28119702119569956 0.03838522713425546 0.28641964755558996 8.613578493397274 0.015943995358533056 0.010420651362946865 4.202162582115694e-08 7.376527148705469 0.054441725591223844 RPS(ph)ALPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPSALPPK 8 1 Q8N4B1-2;Q8N4B1;Q8N4B1-4 Q8N4B1-2 FAM109A Sesquipedalian-1 1 RPS(1)ALPPK 64.73 0.024624 23874000.0 64938.0 63854.0 69198.0 71694.0 72415.0 71294.0 74681.0 64375.0 62225.0 54202.0 True False 75930.72081603666 70193.00312361548 70847.94275487642 67677.21761508407 58225.80058542707 67555.21713408592 67606.67503638209 62685.22446095056 63134.92290686556 64028.39353720404 1.1858913931975616 1.096279310566014 1.1065082042658128 1.056987593726834 0.9093746909579209 1.0550821815454825 1.055885854720045 0.9790222899240314 0.9860457122070488 1.0 15.966424192964572 -5.82877220744605 2.6941179850766304 1.001259824760622 1.131751347469099 0.6341199355050062 0.04479347229191454 0.1841371672243842 2.714070618876158 0.013605160821171516 0.023141353849946464 1.4832958872502564e-06 5.82877220744605 0.13049152270847708 RPS(ph)ALPPK ddPTM_PC-9_Lapatinib_30min_R1 1 RPSALPPK 8 1 Q8N4B1-2;Q8N4B1;Q8N4B1-4 Q8N4B1-2 FAM109A Sesquipedalian-1 1 RPS(1)ALPPK 57.174 0.037877999999999995 13989000.0 124050.0 109210.0 121320.0 117980.0 107830.0 112410.0 97775.0 110030.0 118840.0 86134.0 True False 122281.02425201637 108957.13095484216 111345.53790874314 126656.64276974248 101487.65140193676 107602.48634050859 102837.3110832507 115142.39548426354 105454.98775932127 101022.14713365932 1.2104377873718135 1.078546972582995 1.102189381912713 1.2537512452805715 1.0046079427282568 1.0651375900587723 1.0179679803002977 1.139773789720804 1.0438798892266365 1.0 16.62431208481256 -6.283412824649566 24.90895653354504 1.0518490476759972 1.151108057198835 0.46935656017898586 0.0597934998613974 794.0173168692845 900090.6264867114 0.018453314695657568 0.020939557827144392 5.20699517629918e-07 6.283412824649566 0.09925900952283784 RPS(ph)ASSPNNNTAAK ddPTM_PC-9_AZD4547_30min_R2 3 RPSASSPNNNTAAK 14 1 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 RPS(0.93)AS(0.056)S(0.014)PNNNTAAK;RPS(0.999)AS(0.001)SPNNNTAAK;RPS(1)ASSPNNNTAAK 149.31 3.4801e-05 7298400.0 35903.6 40499.6 47727.4 76438.5 64094.9 63750.9 34740.9 56806.2 48824.799999999996 53315.4 True False 47320.197958727294 53590.303687156505 47094.50349147082 58816.784788052486 55196.42949350727 59764.54614506792 37832.77279795897 48028.10706661432 51405.57925019525 51448.84407394474 0.9197524028084371 1.0416230850616188 0.915365628502447 1.14320906225839 1.0728410032726161 1.1616304937613653 0.7353473820244416 0.9335118782763326 0.9991590710242721 1.0 15.65085104330579 -7.245199472838055 24.93543819031563 0.9114638797025664 1.0425592532038515 0.2665307670302399 0.10174389491968595 1076.7784628362172 1653333.7304755445 0.03949367779596273 0.03049220703488513 5.685917148750944e-08 7.245199472838055 0.13109537350128508 RPS(ph)ASSPNNNTAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RPSASSPNNNTAAK 14 1 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 RPS(0.941)AS(0.023)S(0.036)PNNNTAAK;RPS(0.531)AS(0.366)S(0.103)PNNNTAAK;RPS(1)ASSPNNNTAAK;RPS(0.333)AS(0.333)S(0.333)PNNNTAAK 174.47 0.00019048 21251000.0 33494.399999999994 28399.5 53901.5 42065.4 53282.4 44286.2 39384.899999999994 36922.3 43224.7 31579.4 True False 39164.34037544517 31218.814674243073 55186.71618257707 39708.61201586684 42842.09621090878 41963.75371060056 35654.077150016776 35953.12874741056 43856.77946440165 37304.495237607145 1.0498557915337532 0.8368646854862408 1.4793583408935291 1.0644457661991382 1.1484432623476193 1.1248980436088667 0.9557581981185324 0.9637747011026636 1.175643288699134 1.0 15.187061867033904 -7.234827161712511 22.923605284269755 1.020775271794335 1.1200322912699463 0.07716744463127279 0.15812544745700793 733.5409176405651 631867.4411058694 0.06099988869894094 0.047226041331159055 5.8233492632398703e-08 7.234827161712511 0.09925701947561127 RPS(ph)ASSPNNNTAAK ddPTM_PC-9_Lapatinib_30min_R1 2 RPSASSPNNNTAAK 14 1 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 RPS(0.998)AS(0.002)SPNNNTAAK;RPS(0.997)AS(0.003)S(0.001)PNNNTAAK 165.58 0.00069638 3831200.0 6586.4 4510.9 5000.8 4265.6 8749.7 10342.5 13734.5 11110.599999999999 10974.099999999999 10346.8 True False 6492.4767282021685 4500.455288198872 4589.653527646238 4579.306453624463 8235.059848572062 9900.175384545053 14445.605206575383 11626.839037239442 9738.081295603886 12135.230593755623 0.5350105775116442 0.3708586543476688 0.3782090082415012 0.3773563607419886 0.6786076115281685 0.8158209527258053 1.1903857199061878 0.9581061478322643 0.8024636384425008 1.0 13.566913902402478 -6.627833762338347 2.0204964606706053 0.9819307016801806 0.4094902975150701 0.8539845804144692 0.10558752792308457 0.11653586596893976 0.972339311022075 0.04140882439159842 0.0416846186637185 2.355950913642595e-07 6.627833762338347 -0.5724404041651106 RPS(ph)DENTIAPSEVQK ddPTM_PC-9_AZD4547_30min_R2 1 RPSDENTIAPSEVQK 15 1 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 RPS(0.988)DENT(0.012)IAPSEVQK 108.25 0.0015898 0.0 5325.7 4452.7 7392.5 8639.8 7472.6 4093.8 4718.7 7803.3 6067.8 4865.2 True False 7019.161818558414 5891.948197705694 7294.470619826307 6648.027593579363 6435.158476465094 3837.8140388399083 5138.655158666842 6597.479286995285 6388.531520340785 4694.87082885163 1.4950702744414606 1.2549755706797305 1.5537106100979867 1.4160192763398087 1.370678493840296 0.8174482704093142 1.094525354582282 1.4052525676428536 1.3607470265381991 1.0 12.196869749859824 -6.548063889873302 24.999539633781083 1.1512123902709859 1.4221695923075575 0.40382863440080075 0.1721997346931601 264.66738668363445 262714.9587295943 0.06040481820670325 0.06040687593850482 2.830975495065426e-07 6.548063889873302 0.2709572020365716 RPS(ph)DSGPPAER ddPTM_PC-9_AZD4547_30min_R2 2 RPSDSGPPAER 11 1 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 RPS(0.995)DS(0.005)GPPAER;RPS(0.999)DS(0.001)GPPAER 79.804 0.027025999999999998 0.0 7260.8 8300.4 14304.5 15865.099999999999 12067.9 12277.7 8469.8 15077.6 12597.9 12641.2 True False 9569.583365977984 10983.341976831221 14114.812983605734 12207.64630835158 10392.480392116946 11509.973478104626 9223.595791823263 12747.703368779883 13263.799274877414 12198.635435681825 0.784479822881362 0.9003746390111972 1.1570813029069598 1.0007386787413448 0.8519379439538168 0.9435459842038711 0.7561170132885215 1.045010602701676 1.0873182779181936 1.0 13.574432153544224 -7.948107619871417 24.999902638584658 1.0511640903600121 0.9227724558813623 0.22975094758137715 0.10851445796826667 154.61389037080355 74487.11235545539 0.06296122408017978 0.03024557950717259 1.12691816684261e-08 7.948107619871417 -0.12839163447864987 RPS(ph)DSGPPAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPSDSGPPAER 11 1 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 RPS(0.998)DS(0.002)GPPAER 89.74700000000001 0.010313 0.0 11427.0 11039.0 12437.0 13591.0 15382.0 13761.0 11878.0 13163.0 11528.0 9492.9 True False 13361.365406462326 12134.87896579057 12733.545247585153 12829.540332616505 12368.00752061091 13039.348935144002 10752.829850727032 12817.485197351347 11696.57519116668 11213.887624244948 1.1915016320989726 1.082129531916692 1.1355156814711282 1.1440760566280725 1.1029188034549857 1.1627857681534388 0.9588851084506066 1.143001038251832 1.0430437314065943 1.0 13.452998897113286 -7.231284792507869 24.995184777324116 1.0481491796427878 1.1327919343017951 0.462769000682974 0.05220120653406192 694.9862996814912 576075.7838565139 0.01889841126710311 0.014637454468410771 5.8710422739774565e-08 7.231284792507869 0.08464275465900739 RPS(ph)DSGPPAER ddPTM_PC-9_Lapatinib_30min_R1 2 RPSDSGPPAER 11 1 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 RPS(0.753)DS(0.247)GPPAER;RPS(0.963)DS(0.037)GPPAER 107.93 0.0033034999999999996 93728000.0 128179.0 91067.0 150936.0 104667.8 85199.0 109037.0 83578.0 78160.0 102358.0 83670.0 True False 126351.14395485005 90856.13995663961 138526.62470980923 112365.41917354496 80187.76232767885 104373.74168766152 87905.25988970522 81791.5989371081 90829.36416247551 98132.2480167329 1.2875598644525643 0.9258540570796604 1.4116320323792901 1.1450407123495745 0.8171397674901499 1.0636028807764024 0.8957836151345087 0.8334833919545133 0.9255812028986419 1.0 16.582439689374823 -6.145635574454546 5.837580558239812 0.9207715639164236 1.1946192422467194 0.5033757643653799 0.1320157214274343 0.19571692890575218 8.707131731513151 0.03797905618911695 0.04941894444121101 7.150961264418838e-07 6.145635574454546 0.2738476783302959 RPS(ph)EGNEPSTK ddPTM_PC-9_AZD4547_30min_R2 2 RPSEGNEPSTK 11 1 F2Z329;A0A087WWU1;Q96Q45-2;Q96Q45;Q96Q45-5;Q96Q45-3 F2Z329 TMEM237 Transmembrane protein 237 1 RPS(0.975)EGNEPS(0.02)T(0.005)K;RPS(0.999)EGNEPS(0.001)TK 99.161 0.0047457 0.0 25380.7 36255.0 36522.0 30766.0 34570.0 20318.5 29561.0 29897.0 24650.1 19347.0 True False 33451.23464864444 47973.71974483349 36037.694416949125 23673.374029961655 29770.55222163615 19047.98098299103 32191.87173275491 25277.105614714023 25953.05396182346 18669.667418768484 1.7917423968150685 2.569607624429659 1.9302804709161925 1.2680126270574579 1.5945946734813297 1.020263540626451 1.724287370025277 1.3539130102180144 1.3901187085814417 1.0 14.188408607190315 -5.628401623730192 4.241620891366967 1.3655578958812011 2.1968044253185672 0.6221628087541266 0.274869691656734 0.12609935212586787 4.042947738954521 0.07067363149685406 0.12770334716111642 2.3528724050566438e-06 5.628401623730192 0.8312465294373661 RPS(ph)EGNEPSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RPSEGNEPSTK 11 1 F2Z329;A0A087WWU1;Q96Q45-2;Q96Q45;Q96Q45-5;Q96Q45-3 F2Z329 TMEM237 Transmembrane protein 237 1 RPS(1)EGNEPSTK;RPS(1)EGNEPSTK;RPS(1)EGNEPSTK;RPS(1)EGNEPSTK 104.81 0.0024118000000000004 8529900.0 76173.0 71294.0 66101.1 54779.4 109849.0 52705.8 58474.5 53314.6 50885.5 42096.3 True False 89067.58441467195 78371.59715436831 67677.20091381777 51710.28781521102 88324.87700764465 49941.81506474183 52935.37204128116 51915.1482414881 51629.60417159195 49728.02595587254 1.7910943115600124 1.5760045899250736 1.3609468627182768 1.0398620661334415 1.7761589226570553 1.004299167416358 1.0644977560190052 1.0439816832374638 1.038239567711914 1.0 15.60177154143214 -1.5228787452843406 0.25710057080691545 0.9637863316580862 6.371060401027873 0.5746915476665962 0.2034407838294836 37.57543486365822 0.5164379455192609 0.25548072781639236 88.68549088713921 0.029999999999723477 1.5228787452843406 5.4072740693697865 RPS(ph)EGPQPLVR ddPTM_PC-9_Lapatinib_30min_R1 2 RPSEGPQPLVR 11 1 Q5T5Y3-2;Q5T5Y3;Q5T5Y3-3 Q5T5Y3-2 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1 1 RPS(1)EGPQPLVR;RPS(1)EGPQPLVR 68.069 0.017481 8014600.0 39819.0 29496.0 31246.0 23716.0 25604.0 29001.0 24483.7 22968.8 32960.0 22412.8 True False 39251.17375808973 29427.70382422884 28677.07449304799 25460.15375425677 24098.023059400795 27760.69483463294 25751.346186335843 24036.01429972688 29247.69771581306 26286.82261682124 1.4931882156412641 1.1194850078760648 1.0909296612629478 0.968551967097177 0.9167339625132249 1.056068861546947 0.9796294729762152 0.914375033076305 1.1126372381383638 1.0 14.682052148284189 -3.917043764765593 1.0939833672640384 0.9901374245179622 3.81559414653683 0.8542927378725635 0.060933789171083184 3.1849662147587225 0.7721834136957411 0.018262728525613448 16.358776120154754 0.00012104761451847329 3.917043764765593 2.8254567220188678 RPS(ph)GTGTGPEDGRPSLGSPYGQPPR ddPTM_PC-9_AZD4547_30min_R2 2 RPSGTGTGPEDGRPSLGSPYGQPPR 25 2 P50479;P50479-2;C9J542 P50479 PDLIM4 PDZ and LIM domain protein 4 1 RPS(0.96)GT(0.033)GT(0.007)GPEDGRPSLGSPYGQPPR;RPS(0.617)GT(0.293)GT(0.089)GPEDGRPSLGSPYGQPPR 63.323 0.004003199999999999 88810000.0 12196.5 19968.8 15994.9 18319.2 20155.9 9582.7 19245.2 22625.9 21564.0 13698.7 True False 16074.733297040331 26423.324088832753 15782.797175118 14095.991468818615 17357.601201159283 8983.492254138257 20957.98551710751 19129.58704645811 22703.829016221476 13219.11268255977 1.2160221100352702 1.9988727476159238 1.1939377138331342 1.0663341638214288 1.313068555959849 0.6795836051833003 1.5854305822476107 1.4471158167594822 1.7175002257280911 1.0 13.690337720431868 -5.321082978768009 24.99964305255619 1.2535871620428967 1.6074529857219966 0.1557746007646622 0.332439916447822 404.92960895991206 169725.57466151676 0.08715243257567845 0.1814223607096707 4.774380429208524e-06 5.321082978768009 0.3538658236790999 RPS(ph)GTGTGPEDGRPSLGSPYGQPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPSGTGTGPEDGRPSLGSPYGQPPR 25 2 P50479;P50479-2;C9J542 P50479 PDLIM4 PDZ and LIM domain protein 4 1 RPS(0.585)GT(0.391)GT(0.024)GPEDGRPSLGSPYGQPPR;RPS(0.761)GT(0.216)GT(0.022)GPEDGRPSLGSPYGQPPR 73.809 0.0005842999999999999 92301000.0 53345.1 59673.0 54809.0 54689.0 62050.7 47743.8 58217.4 51895.3 36491.0 41462.6 True False 62375.371816248706 65596.94107488182 56115.85442429003 51624.95263413026 49892.310769676995 45240.031079843626 52702.62641452399 50533.103362615446 37024.61184081045 48979.441162239 1.2735010922161638 1.3392750002516194 1.1457022189863793 1.0540126920421222 1.0186378118201516 0.9236534759551667 1.076015266077707 1.0317207008391562 0.7559214838358507 1.0 15.579888692915084 -5.62361408226342 1.32328623862153 0.9688196953708622 1.3271571656844425 0.7145412703181181 0.08419755393271322 0.2672812967945633 0.8921333850520661 0.027971104329096972 0.08496546624358356 2.3789533056182882e-06 5.62361408226342 0.3583374703135803 RPS(ph)GTGTGPEDGRPSLGSPYGQPPR ddPTM_PC-9_Lapatinib_30min_R1 1 RPSGTGTGPEDGRPSLGSPYGQPPR 25 2 P50479;P50479-2;C9J542 P50479 PDLIM4 PDZ and LIM domain protein 4 1 RPS(0.808)GT(0.146)GT(0.044)GPEDGRPSLGS(0.001)PYGQPPR 42.618 0.022661 29881000.0 23765.0 18569.0 25149.0 25391.0 35757.0 34513.0 22649.0 31124.0 26958.0 30675.0 True False 23426.106742032745 18526.004621375956 23081.346297947366 27258.33884189298 33653.84356096679 33036.95944373249 23821.654397591894 32570.134663748177 23921.70615967502 35977.13287813177 0.6511387892244186 0.5149383271905124 0.6415560232699105 0.7576573412402633 0.935423166569864 0.9182766051881132 0.662133207731836 0.9053010081174507 0.6649141898190424 1.0 15.134792598175624 -5.795085656234392 2.852616646017011 0.8374904054714759 0.5838012324616647 0.5027582156510895 0.10897608719822419 0.2098728894937558 3.483687653067412 0.030934358256399723 0.053323262345891326 1.602929212550701e-06 5.795085656234392 -0.2536891730098112 RPS(ph)ILPEGSSDSR ddPTM_PC-9_AZD4547_30min_R2 4 RPSILPEGSSDSR 13 1 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 RPS(1)ILPEGSSDSR;RPS(1)ILPEGSSDSR;RPS(1)ILPEGSSDSR;RPS(1)ILPEGSSDSR 114.54 0.00044541 38006300.0 56699.7 51194.2 59578.5 76715.5 105434.0 71533.0 68339.2 126853.0 88844.0 88344.0 True False 74729.02517297574 67741.7239928548 58788.45016209966 59029.92671765981 90796.30902331475 67060.0302018505 74421.25640942749 107250.78364194807 93540.11246137913 85251.10344982061 0.876575459424543 0.7946140431217766 0.6895916625490126 0.6924241954522645 1.065045557759356 0.7866177385178657 0.8729653153783792 1.2580574245009817 1.0972305187397073 1.0 16.37943088736698 -7.644943477906896 6.008203624964154 1.1310589976330403 0.8175439706833392 0.5769566159066912 0.11546952102763373 0.14599655636017037 7.074717471704011 0.05695056281366852 0.03230228375581607 2.264939063275342e-08 7.644943477906896 -0.3135150269497011 RPS(ph)ILPEGSSDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RPSILPEGSSDSR 13 1 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 RPS(1)ILPEGSSDSR;RPS(1)ILPEGSSDSR;RPS(1)ILPEGSSDSR 101.08 0.00095975 36062300.0 71373.0 76326.0 74846.0 68156.0 86437.0 55128.0 47837.0 64939.0 44307.0 36630.9 True False 83455.03921899333 83903.14085903908 76630.6124950356 64337.44028473339 69500.29034319619 52236.99063270248 43305.53305011192 63234.420058557946 44954.90605439121 43271.792199955155 1.9286245144031686 1.9389800281747063 1.7709137661997512 1.4868217148815035 1.6061338532511307 1.2071834323690576 1.000779742378149 1.461331200851521 1.03889632873671 1.0 15.401139254051861 -6.026790450331279 0.58629086719692 1.0916827259652049 2.0863640392349083 0.829393577036735 0.14479765272936587 0.47935315140024753 0.30864318481909964 0.09987261158575406 0.2724837500847594 9.401768420541939e-07 6.026790450331279 0.9946813132697034 RPS(ph)ILPEGSSDSR ddPTM_PC-9_Lapatinib_30min_R1 4 RPSILPEGSSDSR 13 1 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 RPS(1)ILPEGSSDSR;RPS(0.841)ILPEGS(0.115)S(0.043)DSR;RPS(0.998)ILPEGSS(0.001)DS(0.001)R;RPS(0.999)ILPEGS(0.001)S(0.001)DSR 94.61 0.0051920000000000004 26574300.0 62575.6 86180.0 89491.0 90429.0 76266.6 59540.7 57328.8 64155.7 88956.0 98863.0 True False 61683.26046904037 85980.45550488343 82133.39542524992 97079.4503223006 71780.74853390477 56994.28305715075 60297.004752027235 67136.60803389769 78936.8385317922 115951.33782333275 0.5319754099174172 0.7415218928813574 0.7083436635322918 0.837243037852776 0.6190592526260651 0.49153622655039225 0.5200199142496977 0.5790067565773948 0.6807755737330339 1.0 16.82315994004344 -8.570950314421438 17.201996229580224 1.0000000027492764 0.6332381766573268 0.5379125363849988 0.10260518274577901 305.33173170773495 109261.47963030948 0.11068760107353422 0.02858019114581239 2.685651680795984e-09 8.570950314421438 -0.3667618260919495 RPS(ph)LGELLLR ddPTM_PC-9_AZD4547_30min_R2 2 RPSLGELLLR 10 1 Q8N612;Q8N612-2 Q8N612 FAM160A2 FTS and Hook-interacting protein 1 RPS(1)LGELLLR;RPS(1)LGELLLR 113.54 0.00059248 7658200.0 11454.400000000001 11021.2 13893.8 14863.4 13495.9 9668.6 13430.6 13945.3 12674.2 12593.099999999999 True False 15096.66093367925 14583.587368687315 13709.559133952342 11436.87276724086 11622.227241191187 9064.020913558925 14625.897381480258 11790.374316114372 13344.132337107874 12152.219402041324 1.2422966072471766 1.200076042590012 1.1281527003741734 0.9411344865382943 0.9563872126303851 0.7458737053444209 1.203557712184114 0.9702239505430449 1.0980819137339088 1.0 13.568932201850632 -5.55186066430748 3.158176384316218 0.9844573210134702 1.2171784346531833 0.42462318047763803 0.11082217190402904 0.23804836404658528 4.862184603337619 0.031500137542819835 0.06460204416735182 2.8063338560478605e-06 5.55186066430748 0.23272111363971315 RPS(ph)LGELLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPSLGELLLR 10 1 Q8N612;Q8N612-2 Q8N612 FAM160A2 FTS and Hook-interacting protein 1 RPS(1)LGELLLR 80.37100000000001 0.0081359 2723400.0 6980.8 5799.9 7448.7 6968.0 7233.4 4556.3 6979.7 6170.9 5163.7 5941.0 True False 8162.511562915222 6375.67574179624 7626.305257352056 6577.605550560801 5816.067195396371 4317.35960709226 6318.532287347997 6008.92041360901 5239.2093437393605 7018.056271069872 1.1630729717233919 0.9084674581590803 1.0866691520826832 0.9372403549505985 0.828729062685292 0.6151788244972418 0.9003251104432601 0.856208639759592 0.7465328206809413 1.0 12.776855800037959 -6.076442909320155 3.0204933017448723 0.8107679435300803 1.037548559335083 0.45358088643593286 0.11137292643651095 0.2347831999841429 4.178149724535728 0.03335212055310722 0.0467480380649655 8.386043110690127e-07 6.076442909320155 0.22678061580500275 RPS(ph)LGELLLR ddPTM_PC-9_Lapatinib_30min_R1 1 RPSLGELLLR 10 1 Q8N612;Q8N612-2 Q8N612 FAM160A2 FTS and Hook-interacting protein 1 RPS(1)LGELLLR 96.37100000000001 0.0025474 2675800.0 6712.5 6326.6 5742.0 5390.8 7283.7 4906.9 5043.3 4839.3 6548.6 4400.4 True False 6616.778519078262 6311.951146405148 5269.914924760976 5787.257415181631 6855.287086305167 4697.043325542576 5304.417396943577 5064.151544733215 5811.027708184876 5161.003276835563 1.2820721406585307 1.2230085523749719 1.0211028054204592 1.1213434878363517 1.328285745733617 0.9101027597918013 1.0277880312054262 0.9812339332282439 1.125949238255061 1.0 12.333435831283452 -6.770945529525359 24.999940949949824 1.0090152533013788 1.1829385121892741 0.49616885693340096 0.09338440664675982 193.35171866254046 508486.8088795631 0.03382839190699469 0.030219008160515416 1.6945503225400728e-07 6.770945529525359 0.1739232588878954 RPS(ph)LPALHFIK ddPTM_PC-9_AZD4547_30min_R2 1 RPSLPALHFIK 11 1 P00519-2;R4GRW0 P00519-2 ABL1 Tyrosine-protein kinase ABL1 1 RPS(1)LPALHFIK 56.599 0.036626 2973400.0 20970.0 16730.0 15919.0 29183.0 30468.0 17732.0 18585.0 34466.0 22958.0 25500.0 True False 27638.023796903704 22137.645327018734 15707.903658710185 22455.310222855453 26238.04411596211 16623.215236872635 20239.02899608437 29140.071649889065 24171.513010314073 24607.252761595922 1.123165761926819 0.8996390430697954 0.6383444674175581 0.9125484441685028 1.0662727924228639 0.6755412884942676 0.822482265377915 1.1842066212026492 0.9822922227237857 1.0 14.586795978895347 -7.74722255995737 24.9808325555803 1.0624370930696827 0.8694741456998829 0.22870383700376362 0.14974747227138643 320.0739952453015 562414.3695673535 0.07264895579635623 0.04168943223445656 1.7896884694405436e-08 7.74722255995737 -0.1929629473697998 RPS(ph)LPALHFIK ddPTM_PC-9_Lapatinib_30min_R1 1 RPSLPALHFIK 11 1 P00519-2;R4GRW0 P00519-2 ABL1 Tyrosine-protein kinase ABL1 1 RPS(1)LPALHFIK 59.248000000000005 0.031465 2913400.0 21779.0 16242.0 18490.0 18202.0 13059.0 13866.0 11005.0 8753.6 15979.0 14708.0 True False 21468.42746622056 16204.392646905504 16969.823573464026 19540.635800091997 12290.895294981832 13272.98350322473 11574.785052121448 9160.324212587913 14179.276753670412 17250.258202821893 1.2445278913395417 0.9393710202120162 0.9837431633741 1.1327735254939797 0.7125050043002382 0.7694368018823893 0.6709919884113955 0.531025339150542 0.821974754635898 1.0 14.074330335941289 -6.268008985154596 24.76922245943039 0.7244627739886128 1.0588829301486278 0.5680228954797271 0.13701282237602794 322.3189193074912 1215229.1078663312 0.04104912778701937 0.04764579992426826 5.394994606505268e-07 6.268008985154596 0.33442015616001497 RPS(ph)PAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPSPAEK 7 1 B5MBZ0;Q9HC35;Q9HC35-2 B5MBZ0 EML4 Echinoderm microtubule-associated protein-like 4 1 RPS(1)PAEK;RPS(1)PAEK 82.645 0.010167 9490900.0 27401.0 62350.0 45852.0 27262.0 121359.0 110711.0 32560.0 67418.0 105619.0 151998.0 True False 32039.448105581043 68539.69594320515 46945.28557467832 25734.598524596524 97579.57513287102 104905.12026442325 29475.68108601382 65648.34893527557 107163.47806348297 179554.03418449365 0.17843903230077346 0.3817218379665026 0.26145491961735345 0.14332509231262358 0.5434552087680024 0.5842537637256991 0.16416050588831244 0.36561890259631374 0.5968313580377224 1.0 17.454058541990094 -14.522878745244943 0.17346897280106247 3.6131394153761907 0.20828117130796667 0.6696569901476344 0.1453761799351557 84.78330020797557 0.803291384934628 75.85815976458423 0.5232210888974392 3.0000000002444935e-15 14.522878745244943 -3.404858244068224 RPS(ph)PGEMR ddPTM_PC-9_AZD4547_30min_R2 2 RPSPGEMR 8 1 A0A0G2JHC2;Q6NYC8;Q6NYC8-3;Q6NYC8-2 A0A0G2JHC2 PPP1R18 Phostensin 1 RPS(1)PGEMR;RPS(1)PGEMR 65.278 0.023938 4676400.0 2791.9 7693.5 9621.2 8425.4 9569.0 9988.3 6499.5 8325.0 6308.2 7407.7 True False 3679.6661248724563 10180.273420407564 9493.616601619598 6483.054201132382 8240.509522963159 9363.730022019798 7077.942908800129 7038.5625394686485 6641.638573554455 7148.358677728402 0.5147567841463961 1.4241413839690877 1.3280834146163005 0.9069290579012413 1.152783442251924 1.3099132883739677 0.9901493794445902 0.9846403708585809 0.929113783034881 1.0 12.803396309863771 -7.487411737646074 24.37200128660561 0.9716050758995678 1.1259092764975338 0.06146719433757997 0.24261860499568405 1173.199320978322 806194.0023492355 0.09984000566824199 0.06727480381280954 3.255279343324151e-08 7.487411737646074 0.154304200597966 RPS(ph)PGEMR ddPTM_PC-9_Lapatinib_30min_R1 2 RPSPGEMR 8 1 A0A0G2JHC2;Q6NYC8;Q6NYC8-3;Q6NYC8-2 A0A0G2JHC2 PPP1R18 Phostensin 1 RPS(1)PGEMR;RPS(1)PGEMR 71.153 0.016589 8392600.0 2711.48 4012.2799999999997 5905.2 4440.1 4028.7 3365.1 3343.54 5387.5 7343.8 1960.1599999999999 True False 2672.8137979754656 4002.9898121737456 5419.697250731193 4766.639765739396 3791.739786728946 3221.1825174312353 3516.652141133132 5637.822918035705 6516.663910357649 2298.971044250978 1.1626130762539848 1.7412093215284272 2.357444763945242 2.073379644193128 1.6493203758311463 1.4011409693421 1.529663520524628 2.452324457123621 2.834600255907454 1.0 11.166772579957591 -7.760064501681543 24.99993421405294 2.232596786114908 1.7294926874387784 0.08287460426403304 0.540206413450647 71.10327811239614 1292981.2224242254 0.2699691698551591 0.14490322564724356 1.7375427486751247e-08 7.760064501681543 -0.5031040986761295 RPS(ph)PHDEEEFEVEEAAEAQAEPK ddPTM_PC-9_AZD4547_30min_R2 1 RPSPHDEEEFEVEEAAEAQAEPK 23 1 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 RPS(1)PHDEEEFEVEEAAEAQAEPK 60.635 0.037852 0.0 3947.6 4037.2 4507.4 5302.5 5793.0 5600.6 4437.8 5203.3 4540.7 4256.9 True False 5202.854684819121 5342.145948251045 4447.628930917159 4080.090547808349 4988.7419444587285 5250.393596640477 4832.755602842248 4399.249544939005 4780.712131977222 4107.867226699516 1.2665586295006368 1.3004670437080352 1.0827100014356175 0.9932381751020019 1.2144360246197525 1.278131280026528 1.1764634386017256 1.0709327498088592 1.1637942192738069 1.0 12.004173836698484 -14.522878745280327 0.10132347970740485 0.47581549388916744 1.278668879523204 0.2745955990543436 0.09146312492076167 296.04413338397325 2.0273096657167633 32.90312950440199 1.661866997777222 3.0000000000000748e-15 14.522878745280327 0.8028533856340365 RPS(ph)PLSENVSELK ddPTM_PC-9_AZD4547_30min_R2 2 RPSPLSENVSELK 13 1 Q99618;J3KMY0 Q99618 CDCA3 Cell division cycle-associated protein 3 1 RPS(0.997)PLS(0.003)ENVSELK;RPS(0.996)PLS(0.004)ENVSELK 101.9 0.00086489 8904800.0 43455.0 48062.0 44922.0 48943.0 46954.0 51053.0 53044.0 64425.0 46727.0 54807.0 True False 57272.786079849764 63597.10159636431 44326.30492848664 37659.94751181219 40435.24758503628 47860.64783938973 57764.813240155985 54469.59658922134 49196.89382493886 52888.22361195248 1.082902434010024 1.2024813323847707 0.838112946536346 0.7120667880269139 0.7645416091437436 0.9049395984737414 1.092205585575792 1.029900285342756 0.9302050714711583 1.0 15.690658899090824 -9.824171814910494 18.814616516951325 0.9999958368802802 0.9475386821485767 0.009624988721935845 0.14630622547439243 0.0 0.0 0.1604061488108139 0.038904205561501794 1.4990916498551067e-10 9.824171814910494 -0.052457154731703426 RPS(ph)PLSENVSELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPSPLSENVSELK 13 1 Q99618;J3KMY0 Q99618 CDCA3 Cell division cycle-associated protein 3 1 RPS(0.999)PLS(0.001)ENVSELK;RPS(0.998)PLS(0.002)ENVSELK 83.37 0.004340699999999999 6804900.0 41185.0 44440.0 47587.0 42288.0 55639.0 38913.0 45173.0 41113.0 37984.0 28566.0 True False 48156.80705917136 48851.70950627165 48721.654554702494 39918.740459545814 44736.93735790344 36872.33377757855 40893.88641580167 40033.82731282425 38539.444141331944 33744.78967166842 1.4270886713987445 1.4476815526660922 1.4438274776271138 1.1829601205978457 1.3257435530992168 1.0926822818082629 1.2118577953424177 1.186370627950187 1.142085771353586 1.0 15.042377141116292 -1.522878745280338 0.15427369663193077 0.9679045614094279 2.945133995044038 0.7757344758301115 0.07063597197616327 29.898310692565293 0.30138354114596944 0.23078713373584314 13.310764713376908 0.029999999999999964 1.522878745280338 1.9772294336346101 RPS(ph)PLSENVSELK ddPTM_PC-9_Lapatinib_30min_R1 2 RPSPLSENVSELK 13 1 Q99618;J3KMY0 Q99618 CDCA3 Cell division cycle-associated protein 3 1 RPS(0.991)PLS(0.009)ENVSELK;RPS(1)PLSENVSELK 127.49 5.3373999999999994e-05 10136300.0 52081.0 94723.0 80395.0 70321.0 74292.0 77829.0 71448.0 73521.0 73968.0 62312.0 True False 51338.31538951431 94503.67471326391 73785.23343367456 75492.64092397923 69922.29062369182 74500.43509826022 75147.22784225098 76937.05406160626 65636.94492242899 73082.54617447907 0.7024702624200853 1.293108678611765 1.0096149805388264 1.0329777063834946 0.9567577251175352 1.0194011976593707 1.0282513647354683 1.0527418390421819 0.8981206643474864 1.0 16.157239277462637 -8.25183960909398 24.60947518803821 0.9490603279733401 1.0208694297316578 0.029610576497454244 0.13643241006566925 1718.882882154992 4406474.782589121 0.08818086983687436 0.03234479636650597 5.599643658293037e-09 8.25183960909398 0.07180910175831778 RPS(ph)PPEPWDEEDGASCSTFFGSEER ddPTM_PC-9_AZD4547_30min_R2 3 RPSPPEPWDEEDGASCSTFFGSEER 25 1 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 RPS(0.991)PPEPWDEEDGAS(0.008)CSTFFGSEER;RPS(1)PPEPWDEEDGASCSTFFGSEER;RPS(1)PPEPWDEEDGASCSTFFGSEER 128.38 7.1696e-08 10948300.0 45655.4 45884.6 54625.0 68981.0 65449.0 61038.0 54313.0 64869.0 58312.0 52939.0 True False 60172.86750868655 60715.89962774202 53900.636808659074 53078.49619582611 56362.53608197466 57221.28421093125 59146.75178177728 54844.98659132637 61394.25327369261 51085.621723377524 1.1778826503182316 1.1885124929380577 1.0551038626978941 1.0390104770230606 1.103295490601465 1.1201054676554119 1.1577964559587786 1.0735894903717793 1.2017912516781155 1.0 15.640629674875225 -5.244382563183693 24.187241851219838 1.098066960089321 1.1831976013288663 0.29326175488592443 0.05517757246856622 696.5515129382586 987731.2704289932 0.013849300204603412 0.03642456225831177 5.696622446806279e-06 5.244382563183693 0.08513064123954539 RPS(ph)PPEPWDEEDGASCSTFFGSEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPSPPEPWDEEDGASCSTFFGSEER 25 1 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 RPS(1)PPEPWDEEDGASCSTFFGSEER;RPS(1)PPEPWDEEDGASCSTFFGSEER 83.992 5.228400000000001e-06 8455600.0 18055.5 26983.0 27087.0 21048.6 30881.0 25393.3 30401.0 23734.0 21707.3 24533.3 True False 21111.93953761974 29661.693915565447 27732.856808019533 19869.31518248193 24830.089731113367 24061.63064565019 27521.197195820227 23111.007648251667 22024.728196323074 28980.99308450406 0.7284753657702692 1.0234878366340507 0.9569325912039951 0.6855981478807887 0.8567715281085329 0.8302555601007262 0.9496291971628682 0.7974539582154265 0.7599714796557315 1.0 14.822819411764568 RPS(ph)PPEPWDEEDGASCSTFFGSEER ddPTM_PC-9_Lapatinib_30min_R1 3 RPSPPEPWDEEDGASCSTFFGSEER 25 1 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 RPS(1)PPEPWDEEDGASCSTFFGSEER;RPS(1)PPEPWDEEDGASCSTFFGSEER;RPS(1)PPEPWDEEDGASCSTFFGSEER 109.91 1.4153e-07 11643200.0 33692.799999999996 47207.6 58250.0 47301.0 58240.0 58828.0 53119.0 62975.0 59834.0 50704.0 True False 33212.334493497205 47098.29370262628 53460.90985150241 50779.673331510356 54814.43770424549 56312.063574765896 55869.24190673686 65901.0484015404 53094.86484004728 59468.1188411668 0.5584897444327089 0.7919923249703081 0.8989843784077142 0.8538974213584529 0.9217449411952846 0.9469286177551639 0.9394822468818601 1.1081744249814813 0.8928290632810865 1.0 15.859828819120226 -4.213792182844712 0.6484041678930063 0.9773172729507165 1.1732526587249205e-26 0.8054322480891202 0.06036413889624695 2.7410343193722153 0.5130723043224577 0.0267385193761357 2.3410203825339764 6.112344408147114e-05 4.213792182844712 -0.9773172729507165 RPS(ph)PQPSPR ddPTM_PC-9_AZD4547_30min_R2 5 RPSPQPSPR 9 1 Q9UQ35;Q9UQ35-2;I3L4U6 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 RPS(1)PQPSPR;RPS(1)PQPSPR;RPS(0.998)PQPS(0.002)PR;RPS(1)PQPSPR;RPS(1)PQPSPR 112.94 0.00097859 29809000.0 22050.23 19254.059999999998 25491.54 36259.0 28740.35 31438.73 25654.96 29449.1 23779.109999999997 28673.86 True False 29061.744466723863 25477.55836133521 25153.505523723667 27900.047745965683 24750.248497052355 29472.861243171963 27938.20173975704 24898.418267995945 25036.025208584768 27669.996889043738 1.050298074960435 0.9207647714417833 0.9090534279634667 1.0083140904512728 0.8944796270234677 1.0651559290504327 1.0096929844910645 0.8998345163477329 0.9048076625732502 1.0 14.756034861294157 -9.357374726193752 0.0021681657760028545 0.618091560836188 1.3049756235035526 0.0 0.0635428531336335 2101989.542503251 1513.9179768444 241513.5161706819 238095.9832432374 4.391625253832458e-10 9.357374726193752 0.6868840626673646 RPS(ph)PQPSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RPSPQPSPR 9 1 Q9UQ35;Q9UQ35-2;I3L4U6 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 RPS(1)PQPSPR;RPS(0.999)PQPS(0.001)PR;RPS(0.814)PQPS(0.186)PR;RPS(1)PQPSPR 103.43 0.0013104000000000002 23639500.0 35354.06 32432.28 34929.43 39557.090000000004 30371.09 32475.100000000002 44982.61 30144.17 30805.28 27163.899999999998 True False 41338.804083485935 35651.942420928564 35762.280081800964 37340.83449311611 24420.092935193792 30772.048586853798 40721.531534905895 29352.917477888186 31255.748942135913 32088.50004068591 1.2882747411400128 1.111050450339669 1.1144889925193437 1.1636827662798392 0.7610231984739352 0.958974353673031 1.269038175149163 0.9147488178216744 0.9740483008712115 1.0 14.969768732757817 -6.110420183276937 22.73812785216089 0.986403290700775 1.161362216017354 0.3524667383686757 0.12559706363198356 16.23921857548379 3322.070266744866 0.03852692453554734 0.04973811197615648 7.754964547217552e-07 6.110420183276937 0.17495892531657897 RPS(ph)PQPSPR ddPTM_PC-9_Lapatinib_30min_R1 5 RPSPQPSPR 9 1 Q9UQ35;Q9UQ35-2;I3L4U6 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 RPS(0.976)PQPS(0.024)PR;RPS(1)PQPSPR;RPS(1)PQPSPR;RPS(0.994)PQPS(0.006)PR;RPS(0.856)PQPS(0.144)PR 112.94 0.00097859 109985400.0 24859.26 24273.179999999997 25715.04 22521.7 26469.3 22971.020000000004 19973.199999999997 24365.56 24915.3 19912.440000000002 True False 24504.762393770034 24216.976943049718 23600.848674124973 24178.020948188787 24912.427814646042 21988.603022663003 21007.314566381832 25497.67286844996 22109.076544259628 23354.278722341507 1.0492622223579071 1.0369396216840954 1.010557806332404 1.0352715763839566 1.0667179282575725 0.9415235333998111 0.8995060312560846 1.0917773642933366 0.9466820537304509 1.0 14.511399268927777 -6.7578064774735385 24.999996708438672 0.9768593963665131 1.037723136930027 0.3010780156682574 0.04858281730073362 132.13342362298428 909283.2617169401 0.01658781285912694 0.015967555648052873 1.7466002682632007e-07 6.7578064774735385 0.06086374056351396 RPS(ph)PTAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPSPTAR 7 1 B8ZZZ9;F8WA32;A0A669KBL0;Q9BZW7-2;Q9BZW7 B8ZZZ9 TSGA10 Testis-specific gene 10 protein 1 RPS(0.981)PT(0.019)AR 75.652 0.036624000000000004 0.0 0.0 613.54 2127.1 601.25 1150.8 704.07 525.81 0.0 530.33 458.69 True False 0.0 674.4481964553986 2177.818131071673 567.5639117788002 925.3090010869226 667.1473297556018 476.00147026526196 0.0 538.0850729642108 541.8468660119576 0.0 1.2447210434553198 4.019250211966 1.0474618335547872 1.7076946626955352 1.2312470028033329 0.8784796962445797 0.0 0.9930574609106186 1.0 9.0817413718693 -7.101149225583235 2.026696797787566 0.6077759073322807 1.6947101185827151 0.14932172316261316 0.9803067851716916 0.597925005767918 4.848605056084754 0.4737214616701639 0.34195710547886 7.922290701527076e-08 7.101149225583235 1.0869342112504343 RPS(ph)PTSGDSR ddPTM_PC-9_Lapatinib_30min_R1 1 RPSPTSGDSR 10 1 Q8N1G1 Q8N1G1 REXO1 RNA exonuclease 1 homolog 1 RPS(0.916)PT(0.06)S(0.016)GDS(0.007)R 80.318 0.026175999999999998 823380.0 702.01 2588.3 2612.9 2463.0 4846.5 3063.1 2907.2 4758.7 4347.0 3262.4 True False 691.9992086671333 2582.3069503746788 2398.077448085678 2644.1372363271407 4561.4383985856075 2932.098353434852 3057.7205909611494 4979.806574488452 3857.395084060663 3826.30149312525 0.18085328872030978 0.6748832926559323 0.6267350997809047 0.6910425749455148 1.192127281862442 0.7663009197531818 0.7991321636454898 1.3014673787300124 1.0081262783372609 1.0 11.901734839867228 -5.07144449321174 0.5823883817681235 1.0433753597711968 1.3768560974687017e-13 0.6592568564433341 0.17751439750028664 1.8790381596570294 0.6122266988853671 0.10085270682609415 1.2628253486434522 8.483117974941192e-06 5.07144449321174 -1.043375359771059 RPS(ph)PTSGDSRPAAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPSPTSGDSRPAAGR 15 2 Q8N1G1 Q8N1G1 REXO1 RNA exonuclease 1 homolog 1 RPS(0.789)PT(0.105)S(0.105)GDS(0.001)RPAAGR 77.027 0.037513 19027000.0 6799.4 5510.6 5853.8 10772.0 9230.1 7610.4 9292.4 8578.4 8226.7 6334.1 True False 7950.404125728533 6057.655949713334 5993.376792660122 10168.479763295203 7421.528163827251 7211.297226656485 8412.156600849963 8353.22608956611 8346.99992411267 7482.422189291992 1.0625441768183388 0.8095848906230358 0.8009942022834764 1.3589823597293396 0.9918617228586906 0.9637650809087582 1.1242558075496598 1.1163799473277938 1.1155478417213567 1.0 12.869289655684995 -5.712918517067254 24.999988551743204 1.092028654964054 0.882895326863674 0.36489764346748665 0.12359602674235716 122.48000203294545 63105.82538455678 0.03321003051760636 0.05752132354252203 1.9367853122047807e-06 5.712918517067254 -0.2091333281003801 RPS(ph)QDQVGEEGSQDLPAVTNQNSSVGITESASSKK ddPTM_PC-9_AZD4547_30min_R2 1 RPSQDQVGEEGSQDLPAVTNQNSSVGITESASSKK 35 2 Q68DA7-3;Q68DA7-5 Q68DA7-3 1 RPS(0.709)QDQVGEEGS(0.289)QDLPAVT(0.001)NQNSSVGITESASSKK 62.434 5.035e-05 8795400.0 11558.0 9273.6 13135.0 24566.0 23793.0 17001.0 13921.0 16683.0 13910.0 17065.0 True False 15233.203578665383 12271.109844867951 12960.82131774346 18902.688240916537 20489.752647075184 15937.924782431292 15159.942031449576 14105.025687201862 14645.254202172167 16467.55954418175 0.9250431758145679 0.7451686943620939 0.7870517354420452 1.1478742912816828 1.2442494950209266 0.9678376895902838 0.9205943352307977 0.8565340631900367 0.8893396840545549 1.0 14.007339146247993 -5.73569556133269 24.99903940274207 1.0028543721201593 0.8116958193599962 0.33877069996063747 0.11810143940924031 289.0439646207803 280679.5417766108 0.036476199084261016 0.06314962069815858 1.8378262006039366e-06 5.73569556133269 -0.19115855276016303 RPS(ph)QDQVGEEGSQDLPAVTNQNSSVGITESASSKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPSQDQVGEEGSQDLPAVTNQNSSVGITESASSKK 35 2 Q68DA7-3;Q68DA7-5 Q68DA7-3 1 RPS(0.995)QDQVGEEGS(0.005)QDLPAVTNQNSSVGITESASSKK 72.053 1.5200999999999999e-06 7868900.0 11171.0 6635.5 9357.8 13389.0 16312.0 15031.0 13270.0 15757.0 14242.0 10616.0 True False 13062.029662692816 7294.228587508232 9580.925441654123 12638.857737723669 13115.780696671769 14242.747899436785 12012.969533519768 15343.395445921526 14450.26230678311 12540.596763790234 1.041579592161688 0.5816492408534827 0.763992784563341 1.0078354304650918 1.0458657545342915 1.1357312708244753 0.9579264655256329 1.2234980308292907 1.1522786817057105 1.0 13.61431838220899 -5.87527145061369 3.3300889533001836 1.0896773550110013 0.7728754574521969 0.5082754003325338 0.12683177751714467 0.17906094077716803 3.902184100454333 0.03629446789530122 0.057618851021478935 1.3326881908432208e-06 5.87527145061369 -0.3168018975588044 RPS(ph)QDQVGEEGSQDLPAVTNQNSSVGITESASSKK ddPTM_PC-9_Lapatinib_30min_R1 1 RPSQDQVGEEGSQDLPAVTNQNSSVGITESASSKK 35 2 Q68DA7-3;Q68DA7-5 Q68DA7-3 1 RPS(0.996)QDQVGEEGS(0.004)QDLPAVTNQNSSVGITESASSKK 81.765 3.1806e-09 7778900.0 26676.0 20816.0 17781.0 12753.0 14906.0 16433.0 15032.0 9366.8 21308.0 12953.0 True False 26295.59534822073 20767.801830931236 16319.114816644893 13690.898162760875 14029.258386323547 15730.198897193994 15810.283407859108 9802.015723184562 18908.068656812648 15191.908791212416 1.7308947617847148 1.3670304447156851 1.0741977878437827 0.9011967061492772 0.9234691031345982 1.0354326841596722 1.0407042080850553 0.6452129128667772 1.2446144139405182 1.0 13.891015528560468 -4.954647027590938 1.5852874861985127 0.9577590015101807 1.8736856900388754 0.7425975506910629 0.14223646920818028 0.34322559808636516 1.0697208956688993 0.03868398113667502 0.4434086292215434 1.1100766624305286e-05 4.954647027590938 0.9159266885286947 RPS(ph)QEQSASASSGQPQAPLNR ddPTM_PC-9_AZD4547_30min_R2 5 RPSQEQSASASSGQPQAPLNR 21 1 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 1 RPS(1)QEQSASASSGQPQAPLNR;RPS(0.992)QEQS(0.006)AS(0.001)AS(0.001)SGQPQAPLNR;RPS(0.999)QEQS(0.001)ASASSGQPQAPLNR;RPS(1)QEQSASASSGQPQAPLNR;RPS(0.996)QEQS(0.004)ASASSGQPQAPLNR 235.5 1.3392999999999996e-125 222246500.0 37838.9 35035.5 39892.4 54162.799999999996 46923.5 47414.0 44225.1 51935.799999999996 49431.9 48203.9 True False 49870.88310198663 46360.04021845579 39363.40071076887 41676.40326691828 40408.98198356796 44449.19508465372 48161.04822462907 43910.31547595625 52044.76931677601 46516.29613312525 1.072116381735572 0.9966408349834589 0.8462281820142027 0.8959527462729264 0.8687059233590152 0.955561787581804 1.0353586211334775 0.943977038719701 1.1188502448223476 1.0 15.505448606130418 -7.133268407737984 4.589026920802241 1.0195002809692906 0.9304777161014247 0.24794358226336055 0.0727128775444691 0.3586642043347803 11.793698444157343 0.0299767061336429 0.02302275398339449 7.357522387758943e-08 7.133268407737984 -0.08902256486786586 RPS(ph)QEQSASASSGQPQAPLNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RPSQEQSASASSGQPQAPLNR 21 1 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 1 RPS(0.94)QEQS(0.058)AS(0.003)ASSGQPQAPLNR;RPS(0.994)QEQS(0.006)ASASSGQPQAPLNR;RPS(1)QEQSASASSGQPQAPLNR;RPS(1)QEQSASASSGQPQAPLNR;RPS(0.994)QEQS(0.006)ASASSGQPQAPLNR 210.66 7.4025e-25 195550500.0 39604.5 41134.600000000006 49388.200000000004 46480.299999999996 55405.700000000004 39104.399999999994 46563.2 43588.0 38932.5 27377.7 True False 46308.75962546928 45218.17123889926 50565.80199379153 43876.159482165756 44549.35081814539 37053.696424638125 42152.396607625284 42443.861185303525 39501.81415944626 32341.06028824606 1.4318874895483746 1.3981660105105838 1.563517137135081 1.3566704087964605 1.3774857849770705 1.1457168099743722 1.30337089235584 1.3123831070167233 1.221413701572508 1.0 14.981079357294833 -11.060016317090204 0.058554203403848815 1.1478094172485894e-06 2.078491828847049 0.724288387957819 0.07869374293079881 100.42245400326478 0.9424299262257116 24.634481955611765 10.745893672363882 8.70930867172159e-12 11.060016317090204 2.0784906810376316 RPS(ph)QEQSASASSGQPQAPLNR ddPTM_PC-9_Lapatinib_30min_R1 5 RPSQEQSASASSGQPQAPLNR 21 1 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 1 RPS(1)QEQSASASSGQPQAPLNR;RPS(0.715)QEQS(0.267)AS(0.014)AS(0.003)S(0.001)GQPQAPLNR;RPS(0.996)QEQS(0.004)ASASSGQPQAPLNR;RPS(1)QEQSASASSGQPQAPLNR;RPS(0.992)QEQS(0.007)ASASSGQPQAPLNR 149.9 3.6538e-05 315013000.0 32101.800000000003 31699.6 36946.4 30093.4 35015.600000000006 30266.2 32684.1 32410.4 31456.800000000003 25758.100000000002 True False 31644.022445250885 31626.20152381761 33908.80960922834 32306.56902463952 32956.051251318335 28971.785179958177 34376.32277347046 33916.305503982265 27913.803929210837 30210.353264489193 1.047456220329833 1.0468663258232296 1.1224234722566617 1.069387330290319 1.0908859940428626 0.9590018668869095 1.1378987353278707 1.122671595629742 0.9239813809798166 1.0 14.882755433855186 -8.264799782012329 24.99959443499538 0.9619906849173662 1.0738746119266571 0.43199975026024773 0.051632640822078225 291.519505695159 2168696.684413043 0.0434920133927776 0.01297323379221554 5.435008379315597e-09 8.264799782012329 0.11188392700929095 RPS(ph)QGPPAR ddPTM_PC-9_AZD4547_30min_R2 2 RPSQGPPAR 9 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RPS(1)QGPPAR;RPS(1)QGPPAR 57.836000000000006 0.037086 5997370.0 3773.5 6002.25 6014.43 9057.400000000001 9559.8 7885.2 5259.4400000000005 8988.9 8162.099999999999 9907.8 True False 4973.394506324089 7942.359932103892 5934.67472844125 6969.356365435054 8232.586784159601 7392.137197484103 5727.519971114662 7599.872049372945 8593.531942742598 9560.930937699613 0.5201788966714053 0.8307098946595723 0.6207214304875158 0.7289411889750456 0.8610653960168009 0.7731608193440912 0.5990546326959161 0.7948882905749234 0.8988174895038229 1.0 13.222935383392626 -14.522878680475044 0.08816259214378012 1.8971876003618742 0.505563798550306 0.4747551216715873 0.10176818322772183 212.39005337818517 1.3008944950830141 35.57462672193464 2.61228261657715 3.0000004476591434e-15 14.522878680475044 -1.3916238018115683 RPS(ph)QGPPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RPSQGPPAR 9 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RPS(1)QGPPAR;RPS(1)QGPPAR;RPS(1)QGPPAR;RPS(1)QGPPAR 79.036 0.0095037 401474900.0 39967.9 45917.3 45140.100000000006 39834.7 53046.0 41706.100000000006 36734.8 38182.1 35254.3 24278.0 True False 46733.67606799211 50475.666087136124 46216.411178782546 37602.89090483988 42652.01709389719 39518.95869660704 33255.01380707925 37179.860332279015 35769.827442917 28679.409215457734 1.6295201800322798 1.7599967177821279 1.6114840731751425 1.311145938270323 1.487199989841787 1.3779558149094286 1.1595431955116893 1.296395614461949 1.2472302750099065 1.0 14.807727684945332 -1.5228787560164165 0.13607258805295927 0.8952037280709269 3.864673310377877 0.8254617192556603 0.09280411687494354 30.589810861078224 0.2800484499466508 0.4439307349317084 17.562211783450877 0.029999999258377947 1.5228787560164165 2.9694695823069504 RPS(ph)QGPPAR ddPTM_PC-9_Lapatinib_30min_R1 5 RPSQGPPAR 9 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 RPS(1)QGPPAR;RPS(1)QGPPAR;RPS(1)QGPPAR;RPS(1)QGPPAR;RPS(1)QGPPAR 74.611 0.012459 304271060.0 19210.800000000003 19499.300000000003 21619.1 16761.8 22859.7 19355.2 18436.2 17946.2 24678.899999999998 15831.12 True False 18936.85046917076 19454.150568883433 19841.66105013933 17994.518687725653 21515.137389899395 18527.423215174913 19390.7362269806 18780.045967824113 21899.302401661993 18567.507998358564 1.0198918708339777 1.0477523731565512 1.0686227280415554 0.9691402146866684 1.1587520194848664 0.9978411328441493 1.0443370337416746 1.0114467687039284 1.1794421956677208 1.0 14.180492579332183 -1.5228787453294055 0.4717654277077853 1.0569862935495107 0.22935353647596832 0.023647632880337666 0.06488260662799486 533.7338051251664 6.107133760875959 0.03671720532973625 431.165962348763 0.02999999999661051 1.5228787453294055 -0.8276327570735423 RPS(ph)QNAISFFNVGHSK ddPTM_PC-9_AZD4547_30min_R2 3 RPSQNAISFFNVGHSK 16 1 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 RPS(1)QNAISFFNVGHSK;RPS(0.967)QNAIS(0.033)FFNVGHSK;RPS(0.994)QNAIS(0.006)FFNVGHSK 139.43 8.413200000000001e-06 162222100.0 199959.0 171774.0 302859.0 420320.0 310246.0 240220.0 215615.0 302052.0 231033.0 265905.0 True False 263541.8025944242 227296.58627634883 298842.8917754449 323421.71787926595 267173.6981357748 225199.00542530676 234804.31729839832 255376.8038644547 243244.93271678267 256595.7468851829 1.0270700344552064 0.8858158758884481 1.164644758937357 1.2604328863797778 1.0412241877700537 0.8776412242174653 0.9150748605488951 0.9952495587494145 0.947969464301471 1.0 17.969137732165628 -6.564269356154545 8.652676591059986 0.9461392841065333 1.0852783129892023 0.3198736651397378 0.0954627370763383 0.3738112249611663 71.47996456110114 0.034786641924857434 0.03485960104367452 2.72728575334599e-07 6.564269356154545 0.13913902888266905 RPS(ph)QNAISFFNVGHSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPSQNAISFFNVGHSK 16 1 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 RPS(1)QNAISFFNVGHSK;RPS(0.998)QNAIS(0.002)FFNVGHSK 131.56 4.4718e-06 88547000.0 125937.0 105720.0 113734.0 144545.0 138568.0 124154.0 102984.0 127919.0 95416.0 97545.0 True False 147255.64673086972 116215.1829208605 116445.8498985971 136446.61227121289 111416.59511871077 117643.14567937425 93228.60998040684 124561.26179138382 96811.27849066244 115229.13633420467 1.277937606889433 1.0085572678753398 1.0105590790931864 1.1841329078044127 0.966913392421547 1.0209496436575565 0.8090714982885177 1.0809875501462818 0.8401631876323015 1.0 16.81414603088757 -6.371453511086049 6.458353617438242 0.9517164834889063 1.1041016561913424 0.3732408491148316 0.1054637407128343 0.28699944011772127 14.699917356881823 0.031715096905813846 0.035976961634465655 4.25154214865863e-07 6.371453511086049 0.15238517270243612 RPS(ph)QNAISFFNVGHSK ddPTM_PC-9_Lapatinib_30min_R1 5 RPSQNAISFFNVGHSK 16 1 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 RPS(0.991)QNAIS(0.009)FFNVGHSK;RPS(0.972)QNAIS(0.028)FFNVGHSK;RPS(0.994)QNAIS(0.006)FFNVGHSK;RPS(1)QNAISFFNVGHSK;RPS(0.999)QNAIS(0.001)FFNVGHSK 111.35 0.00021484 140000000.0 734348.0 512786.0 619594.0 512556.0 553332.0 487929.0 414391.0 384495.0 624058.0 416660.0 True False 723876.0628570693 511598.6755224786 568653.3730220062 550251.0780766933 520786.0996525688 467061.41408805293 435846.13834926457 402360.0413680073 553770.0164179268 488679.12583544885 1.4812911470681838 1.0469010204760565 1.163653904900957 1.125996689823779 1.0657015454921053 0.9557629728701054 0.8918861381773557 0.8233624480688224 1.1331976078806274 1.0 18.898527954923054 -1.5228787452804933 0.4946344969457445 0.9593970625966434 14.757075048679146 0.6315937683831157 0.1044442990738938 70.47779547562538 0.7599476020313417 0.05957927825193609 1007.6738900570725 0.029999999999989244 1.5228787452804933 13.797677986082503 RPS(ph)SGNASYR ddPTM_PC-9_AZD4547_30min_R2 1 RPSSGNASYR 10 1 Q5T0V7;Q03001-11 Q5T0V7 DST Dystonin 1 RPS(0.663)S(0.205)GNAS(0.132)YR 68.262 0.019001 1882300.0 4906.6 4428.9 5162.6 8145.4 6619.8 4103.8 4130.5 7406.7 4042.7 5288.9 True False 6466.7967363799535 5860.455313140061 5094.140550817085 6267.60387517551 5700.755036065579 3847.188737259075 4498.10649816123 6262.16470403393 4256.388868664374 5103.73722081587 1.2670708652484635 1.1482674478689605 0.9981196778784681 1.2280420413521187 1.1169765976223733 0.7537983581067038 0.8813358336349014 1.2269763181563014 0.8339749255319142 1.0 12.317338334770872 -6.550823820004267 24.89298286914982 0.9481856346732633 1.1509941631167089 0.3889544299818406 0.13360261541442067 237.0084182655461 211121.24422595647 0.04480960031894346 0.044810394700784156 2.813041764016548e-07 6.550823820004267 0.20280852844344555 RPS(ph)SNLNNNVR ddPTM_PC-9_AZD4547_30min_R2 1 RPSSNLNNNVR 11 1 Q9NW75-2;Q9NW75 Q9NW75-2 GPATCH2 G patch domain-containing protein 2 1 RPS(0.954)S(0.046)NLNNNVR 79.88600000000001 0.024652 1816000.0 10053.0 8865.5 10065.0 13838.0 12304.0 11276.0 10796.0 15634.0 10651.0 9216.5 True False 13249.64488461005 11731.09950069842 9931.531523645832 10647.862894968779 10595.8019824996 10570.909937456341 11756.823085376745 13218.124533579918 11213.990115552533 8893.833140284269 1.4897564048729792 1.3190150203698858 1.116676169542843 1.1972186488118044 1.191365052095067 1.1885662537984685 1.3219073148701965 1.4862123366930442 1.2608725550245827 1.0 13.118589622796238 -4.854255223374909 3.6180603926343498 1.237293596024472 1.4999465394510652 0.30846349717854615 0.12139232976294487 0.3356738072932422 7.361546370043783 0.03210467525498974 0.20913201231709094 1.3987650637719274e-05 4.854255223374909 0.2626529434265932 RPS(ph)STSVPLGDK ddPTM_PC-9_AZD4547_30min_R2 2 RPSSTSVPLGDK 12 1 Q9NXR1;Q9NXR1-1;I3L533;I3L2R9;I3L2T8 Q9NXR1 NDE1 Nuclear distribution protein nudE homolog 1 1 RPS(0.914)S(0.074)T(0.011)S(0.001)VPLGDK;RPS(0.951)S(0.049)TSVPLGDK 141.65 3.1566e-05 0.0 22054.5 21782.9 26503.0 36813.0 33214.0 28323.0 25705.0 32702.0 27493.0 26325.0 True False 29067.372237902353 28823.79643717373 26151.552903247433 28326.33160518035 28602.80941537239 26551.95833261583 27992.695202816718 27648.657317201654 28946.22385192808 25403.369762706396 1.144232930883639 1.1346446044921457 1.0294521218062735 1.1150619728712146 1.1259454821368997 1.0452140239912435 1.1019284238389349 1.088385421913256 1.1394639420799517 1.0 14.632732263062207 -10.94735422450484 3.1642035046740773 0.9984954529907125 1.100400553677079 0.4078560297932732 0.03703148973378398 8273317.418165455 11940773.506312435 114470.22165941898 0.009237645965739715 1.1288747925979565e-11 10.94735422450484 0.10190510068636638 RPS(ph)STSVPLGDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPSSTSVPLGDK 12 1 Q9NXR1;Q9NXR1-1;I3L533;I3L2R9;I3L2T8 Q9NXR1 NDE1 Nuclear distribution protein nudE homolog 1 1 RPS(0.625)S(0.238)T(0.126)S(0.011)VPLGDK 100.68 0.004344 19237000.0 25128.0 31134.0 25553.0 18678.0 25792.0 19618.0 18225.0 22070.0 14945.0 14253.0 True False 29381.674099377407 34224.77776256216 26162.28043029214 17631.53221489304 20738.242749421188 18589.197544484767 16498.59606242635 21490.685885097922 15163.542351837787 16836.956073314082 1.7450704255234242 2.032717648815815 1.5538604671991947 1.0471923866831445 1.231709737741164 1.1040711553525948 0.9799037302577501 1.2763997121284778 0.900610673675832 1.0 14.039343718970798 -5.582329946034806 3.2339870324736193 1.0913600408360782 1.883241710702183 0.871120752531299 0.12729242801886745 0.07254234033380658 1.5335520799740525 0.03357756420643198 0.06635686366698804 2.616194654528811e-06 5.582329946034806 0.7918816698661049 RPS(ph)STSVPLGDK ddPTM_PC-9_Lapatinib_30min_R1 3 RPSSTSVPLGDK 12 1 Q9NXR1;Q9NXR1-1;I3L533;I3L2R9;I3L2T8 Q9NXR1 NDE1 Nuclear distribution protein nudE homolog 1 1 RPS(0.982)S(0.014)T(0.004)SVPLGDK;RPS(0.971)S(0.025)T(0.004)SVPLGDK;RPS(0.966)S(0.032)T(0.002)SVPLGDK 147.51 0.00020093 38768500.0 91314.0 140576.0 128625.0 127806.0 109582.0 92703.0 100694.0 91324.0 105194.0 134473.0 True False 90011.8456150634 140250.5049089639 118049.94900685856 137205.27958831796 103136.60220650118 88738.30879124782 105907.442620474 95567.24643465312 93345.94397807166 157716.47887599058 0.5707193456039428 0.8892571398277295 0.7484947029516107 0.8699489144453942 0.6539367537338663 0.5626444961469185 0.6715052439367923 0.60594331750074 0.5918591680674521 1.0 17.26697388124009 -4.512692625246573 17.602720878991956 0.716271931053381 0.3507757801226659 0.09927145969858076 0.13864432194695805 9192307.397616876 265636678.4807334 0.03484344470543703 80577256.9393392 3.071194877576981e-05 4.512692625246573 -0.36549615093071514 RPS(ph)TADGEGDERPFTQAGLGADER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPSTADGEGDERPFTQAGLGADER 24 2 O60303 O60303 KIAA0556 Uncharacterized protein KIAA0556 1 RPS(0.5)T(0.5)ADGEGDERPFTQAGLGADER 55.621 0.0024494 4154100.0 4507.6 4485.2 7643.7 6294.9 8044.3 4401.8 6392.5 4579.3 4352.4 4770.7 True False 5270.6476508418355 4930.461014345851 7825.9547968936795 5942.217161341153 6468.0771614907235 4170.961859073966 5786.956122307843 4459.098227169412 4416.045616068168 5635.590145159577 0.9352432513866907 0.8748792739267309 1.388666420963102 1.054409034064505 1.1477195812485 0.7401109292265363 1.0268589399245567 0.7912389141710994 0.7835994993108434 1.0 12.460350978451835 -6.751360646483693 24.99699152413552 0.8652201609808642 1.0844837615685572 0.32215788504521137 0.15353090368738492 253.7340914791382 629303.2431934145 0.05186320433291269 0.05128702955520836 1.772716771418048e-07 6.751360646483693 0.219263600587693 RPS(ph)TEDTHEVDSK ddPTM_PC-9_AZD4547_30min_R2 1 RPSTEDTHEVDSK 13 1 H0YLN8;Q96QT4 H0YLN8 TRPM7 Transient receptor potential cation channel subfamily M member 7 1 RPS(0.484)T(0.484)EDT(0.032)HEVDSK 69.422 0.014005000000000002 4718400.0 15925.0 23325.0 27515.0 21656.0 24295.0 17819.0 21568.0 25147.0 17881.0 19750.0 True False 20988.818739422575 30864.3501047646 27150.133122018367 16663.54378186471 20922.058612225916 16704.775113119416 23487.510217247658 21261.108970572754 18826.153155215005 19058.55851143213 1.1012804943685848 1.6194482959585248 1.4245638307709667 0.874333899485064 1.0977775994798338 0.8764973018866661 1.2323864999107281 1.115567526149443 0.9878057222387665 1.0 14.218151385100954 -5.747219478274162 24.992771542520007 1.0364722782012707 1.4055327824488548 0.5199846408400403 0.15577800403740752 176.68925507805758 310544.8451362522 0.041099309937930234 0.07075699381616059 1.789701168824721e-06 5.747219478274162 0.3690605042475841 RPS(ph)TEDTHEVDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPSTEDTHEVDSK 13 1 H0YLN8;Q96QT4 H0YLN8 TRPM7 Transient receptor potential cation channel subfamily M member 7 1 RPS(0.497)T(0.497)EDT(0.006)HEVDSK 53.519 0.039547000000000006 2802400.0 19056.0 18418.0 17394.0 19954.0 28718.0 16367.0 17475.0 17489.0 14836.0 17354.0 True False 22281.804426843977 20246.417319678476 17808.738927112347 18836.042071740838 23090.91405388793 15508.685707543196 15819.64149195613 17029.932281127225 15052.948433045527 20500.1428258116 1.0869097164917847 0.987623232272623 0.8687129196333928 0.9188249190159055 1.12637820380521 0.7565159832943363 0.7716844524633126 0.8307226162192853 0.7342850516188821 1.0 14.323346340664186 -6.781029587810421 24.99982787778563 0.8051269309173311 0.9855838152103368 0.45156206625733075 0.09764242836556122 225.21214500927343 287400.0757497244 0.03398101436426993 0.030010066882257314 1.6556571622688867e-07 6.781029587810421 0.18045688429300566 RPS(ph)TEDTHEVDSK ddPTM_PC-9_Lapatinib_30min_R1 2 RPSTEDTHEVDSK 13 1 H0YLN8;Q96QT4 H0YLN8 TRPM7 Transient receptor potential cation channel subfamily M member 7 1 RPS(0.499)T(0.499)EDT(0.002)HEVDSK;RPS(0.373)T(0.373)EDT(0.254)HEVDSK 107.98 0.00043473 6641900.0 62207.0 67995.0 36674.0 30013.0 33917.0 29563.0 33198.0 33218.0 47381.0 16102.2 True False 61319.91677263337 67837.56175510035 33658.805285733906 32220.256140433 31922.06874338762 28298.659404718906 34916.83000093847 34761.42954827104 42044.45283595081 18885.44381516717 3.2469407323849313 3.5920554697591505 1.7822618104797747 1.7060894335221526 1.6903001621677827 1.4984376158526838 1.8488752683109444 1.8406466847421206 2.226288841683684 1.0 14.204987067612267 -5.266225026595816 24.5545004022599 1.7272516672420122 3.4194981875859045 0.8368005766625028 0.30369906599035706 97.84610424034906 502038.604809793 0.07547971259500513 0.1657836050192701 5.417201292400506e-06 5.266225026595816 1.6922465203438923 RPS(ph)TFGIPR ddPTM_PC-9_AZD4547_30min_R2 4 RPSTFGIPR 9 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347 A0A494C1K3 GTF2I General transcription factor II-I 1 RPS(0.5)T(0.5)FGIPR;RPS(0.5)T(0.5)FGIPR;RPS(0.914)T(0.086)FGIPR;RPS(0.5)T(0.5)FGIPR 97.45200000000001 0.0024817 9180200.0 40133.299999999996 42062.6 46221.7 63440.3 56842.6 48544.9 44670.399999999994 59096.5 49435.299999999996 54264.100000000006 True False 52894.85457550192 55658.51287102562 45608.770057277754 48815.118977864404 48950.986164697 45509.379728877655 48645.97906196863 49964.493827472535 52048.34903383482 52364.33037570658 1.010131404259138 1.0629089013777842 0.8709892732331599 0.932220819546873 0.9348154710177841 0.8690912192012075 0.9289907597966152 0.9541703955533173 0.9939657140728309 1.0 15.676296788391593 -5.249898014347402 24.995053919611447 0.9311435572949529 1.0365201612984587 0.4717656863093037 0.04254305355813683 610.8275910271775 1322859.3907081028 0.010827143316736116 0.028091554638279802 5.624733956720286e-06 5.249898014347402 0.10537660400350579 RPS(ph)TFGIPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RPSTFGIPR 9 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347 A0A494C1K3 GTF2I General transcription factor II-I 1 RPS(0.918)T(0.082)FGIPR;RPS(0.73)T(0.27)FGIPR;RPS(0.805)T(0.195)FGIPR 98.40700000000001 0.0020500999999999996 7034600.0 29097.699999999997 31552.7 29498.0 33123.0 32776.0 33196.7 33637.6 36148.9 32912.2 24076.1 True False 34023.36590422851 34685.043531470255 30201.34419178798 31267.225696214908 26353.77808448466 31455.80661254958 30451.20301286543 35200.02967792556 33393.478661234876 28440.906343697246 1.1962827588217273 1.2195477567527226 1.0618980923749943 1.0993751506496556 0.9266152690779099 1.106005773248519 1.070683284311496 1.237654990756868 1.1741355306222567 1.0 14.795679820481547 -5.257068484553465 24.45987045855962 1.0881942397397637 1.2079152740773114 0.2706968013139046 0.08082167231677322 395.41303370808043 2212729.7331423177 0.022224674020620845 0.054768141124512795 5.532628574800091e-06 5.257068484553465 0.11972103433754766 RPS(ph)TFGIPR ddPTM_PC-9_Lapatinib_30min_R1 4 RPSTFGIPR 9 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347 A0A494C1K3 GTF2I General transcription factor II-I 1 RPS(0.871)T(0.129)FGIPR;RPS(0.907)T(0.093)FGIPR;RPS(0.5)T(0.5)FGIPR;RPS(0.976)T(0.024)FGIPR 117.86 0.00084014 14892900.0 44527.7 35650.5 47036.0 36603.9 43705.4 38903.0 35218.0 35268.399999999994 44211.3 38970.7 True False 43892.72683261989 35567.95345761017 43168.88164421062 39295.87291303088 41134.734300122465 37239.209377322324 37041.41571700256 36907.098617624215 39231.757828371534 45706.733569806296 0.9603120460486213 0.7781775392741308 0.944475316274358 0.8597392516141121 0.8999709908672171 0.8147423031323859 0.8104148519042713 0.8074761798774637 0.8583365023985852 1.0 15.480119100022225 -6.7505348443997875 24.982162529769198 0.8431750313450103 0.8839120859580554 0.021092930280252498 0.0703611184587219 595.3872592577569 1364023.0214990466 0.02182588423356807 0.02162112909082655 1.776090762910395e-07 6.7505348443997875 0.04073705461304511 RPS(ph)TIAEQTVAK ddPTM_PC-9_AZD4547_30min_R2 2 RPSTIAEQTVAK 12 1 Q9H0K1 Q9H0K1 SIK2 Serine/threonine-protein kinase SIK2 1 RPS(0.948)T(0.052)IAEQTVAK;RPS(0.994)T(0.006)IAEQTVAK 117.08 0.00095075 2876900.0 13937.7 12654.3 18234.1 16411.4 19668.6 14603.099999999999 16638.2 23000.0 20958.9 21323.0 True False 18369.59867783045 16744.555006676226 17992.303920050705 12628.005283602437 16937.95439474899 13689.965848498472 18118.9675675357 19445.878487420883 22066.744665557606 20576.48826021608 0.892747024930752 0.8137712711187574 0.8744108174589827 0.6137104215211613 0.823170318498805 0.6653208105956322 0.8805665640510723 0.9450533172377528 1.0724252062108617 1.0 14.32870916149566 -7.746121955934654 2.3290026504239347 1.0271588238488205 0.7808001613714736 0.5877508555819688 0.08510181085115034 0.2128635331185198 2.2991381297971336 0.05606617097502609 0.024452318807954572 1.7942297114091038e-08 7.746121955934654 -0.24635866247734695 RPS(ph)TSQTVSTPAPVPVIESTEAIEAK ddPTM_PC-9_AZD4547_30min_R2 3 RPSTSQTVSTPAPVPVIESTEAIEAK 26 1 P12270;P12270-2 P12270 TPR Nucleoprotein TPR 1 RPS(0.226)T(0.226)S(0.226)QT(0.226)VS(0.034)T(0.062)PAPVPVIESTEAIEAK;RPS(0.244)T(0.244)S(0.244)QT(0.244)VS(0.004)T(0.019)PAPVPVIESTEAIEAK;RPS(0.266)T(0.266)S(0.266)QT(0.183)VS(0.003)T(0.015)PAPVPVIESTEAIEAK 79.845 1.7425e-05 25301400.0 46663.0 60021.0 73317.0 94081.0 82098.0 74229.0 60593.0 72152.0 67115.0 69407.0 True False 61500.86334930456 79421.61447537305 72344.76867552314 72392.07898696042 70700.10981463373 69587.44889565856 65985.6596158052 61002.56628801704 70662.56188201183 66977.08205584672 0.9182374248257638 1.185802845354622 1.080142138996153 1.0808485046660972 1.0555865923762202 1.0389740305144266 0.9851975868519495 0.9107976103998078 1.05502598371025 1.0 16.03137990406737 -7.044587012250781 2.268932784897804 0.9801425885700572 1.0733769267547042 0.20598688608874438 0.06921295467713323 0.4172363391258376 4.270109846610083 0.02896874160681496 0.02214534466035939 9.024288849223481e-08 7.044587012250781 0.09323433818464699 RPS(ph)TSQTVSTPAPVPVIESTEAIEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RPSTSQTVSTPAPVPVIESTEAIEAK 26 1 P12270;P12270-2 P12270 TPR Nucleoprotein TPR 1 RPS(0.2)T(0.2)S(0.2)QT(0.165)VS(0.038)T(0.198)PAPVPVIESTEAIEAK;RPS(0.205)T(0.205)S(0.205)QT(0.169)VS(0.067)T(0.149)PAPVPVIESTEAIEAK;RPS(0.247)T(0.247)S(0.247)QT(0.247)VS(0.006)T(0.006)PAPVPVIESTEAIEAK 77.939 2.5229000000000002e-05 15994400.0 16194.399999999998 16671.7 31406.8 35706.7 33158.9 37951.0 44592.6 41439.9 35594.1 40076.0 True False 18935.792066020258 18326.75619657313 32155.657222952286 33706.1693616833 26661.65157815531 35960.782751082785 40368.466105533786 40352.14653420345 36114.596375078574 47341.46155855854 0.3999832587043774 0.38711851288967986 0.6792282317515203 0.7119799062390754 0.563177618527397 0.75960440525482 0.8527084880047571 0.8523637675252225 0.7628534309277079 1.0 15.530816626195175 -4.990354654886336 0.2739966344057204 0.9603138992455839 4.6477715129994416e-15 0.8148475248597795 0.08063176960297988 3.4885647034614333 0.24008830960510172 0.11150115936274077 1.123644641842782 1.0224576887422991e-05 4.990354654886336 -0.9603138992455792 down RPS(ph)TSQTVSTPAPVPVIESTEAIEAK ddPTM_PC-9_Lapatinib_30min_R1 2 RPSTSQTVSTPAPVPVIESTEAIEAK 26 1 P12270;P12270-2 P12270 TPR Nucleoprotein TPR 1 RPS(0.223)T(0.223)S(0.223)QT(0.223)VS(0.024)T(0.085)PAPVPVIESTEAIEAK;RPS(0.282)T(0.215)S(0.215)QT(0.215)VS(0.027)T(0.047)PAPVPVIESTEAIEAK 68.024 0.00016815 10690900.0 25418.0 22899.0 20715.0 16090.7 26937.7 35372.0 36178.0 42471.0 37811.0 26039.0 True False 25055.534658909666 22845.978772410377 19011.892662212413 17274.06375500168 25353.277447555884 33859.22201615932 38051.1198196865 44444.35770800827 33552.32701251844 30539.806455213457 0.8204221822968505 0.7480721531720885 0.6225282629113351 0.5656245327007572 0.8301715167951832 1.1086914406551258 1.245951570632524 1.4552927102922475 1.0986424246572368 1.0 14.898403298691793 -6.756817869233744 2.548819774818207 1.2330207505358421 0.6884572718872531 0.7697463217998645 0.12871993229062997 0.12446287706165873 1.6578925663400483 0.048936019542864966 0.0454447556038264 1.7505806785045878e-07 6.756817869233744 -0.544563478648589 RPS(ph)TYGIPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPSTYGIPR 9 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347;A0A494C0Q7 A0A494C1K3 GTF2I General transcription factor II-I 1 RPS(0.921)T(0.078)YGIPR;RPS(0.881)T(0.104)Y(0.015)GIPR 62.693999999999996 0.027780000000000003 5291200.0 15902.400000000001 15313.1 16757.0 14942.3 14782.2 13600.0 15635.5 13031.3 13625.1 12654.5 True False 18594.36223328316 16833.283367247728 17156.55043127638 14105.13137459021 11885.734024910582 12886.792058568304 14154.392248782833 12689.242182803662 13824.341311343247 14948.66067703311 1.2438814844363448 1.1260730128893837 1.1476981652032172 0.9435715800453692 0.7951036070523455 0.8620700099486084 0.946866917016146 0.848854787526164 0.9247879532500695 1.0 13.86772861172139 -5.787941786551049 3.402014328529803 0.8877736656378826 1.1754370799791707 0.8128926557539558 0.05964117167026453 0.09050039517474838 2.174524934957906 0.016797692393605426 0.02816260746646983 1.6295144404306746e-06 5.787941786551049 0.28766341434128806 RPS(ph)TYGIPR ddPTM_PC-9_Lapatinib_30min_R1 1 RPSTYGIPR 9 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347;A0A494C0Q7 A0A494C1K3 GTF2I General transcription factor II-I 1 RPS(0.952)T(0.045)Y(0.003)GIPR 71.153 0.016387 2031700.0 4689.0 4364.3 5751.2 5331.4 9126.2 6900.1 5426.0 8340.7 7569.1 5389.5 True False 4622.134000142711 4354.194731491791 5278.358536274004 5723.488941029036 8589.414858799544 6604.998807918716 5706.931730378098 8728.23937122235 6716.5882518434655 6321.067893942661 0.731226760682637 0.688838469155555 0.8350422151504081 0.9054623422908855 1.3588550230619403 1.0449181876765063 0.9028429730753128 1.380817215962263 1.0625717623251323 1.0 12.625952595461314 -5.911485980443661 2.745370556693339 1.129304771650121 0.7360058279134101 0.5689686258085171 0.145859046371323 0.19027304446772086 2.9020984514924018 0.043588695312409435 0.06961423656050622 1.2260664809626694e-06 5.911485980443661 -0.3932989437367109 RPS(ph)VASSVSEEYFEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPSVASSVSEEYFEVR 16 1 A6ND36;A6ND36-2;K7EKG0 A6ND36 FAM83G Protein FAM83G 1 RPS(0.995)VAS(0.003)S(0.001)VSEEYFEVR 67.29899999999999 0.011561 1634400.0 5825.2 6795.5 6488.9 8849.6 11080.0 5344.0 6090.1 7415.6 5830.9 6528.2 True False 6811.291307055603 7470.112330105063 6643.619985290285 8353.785602790305 8908.953538445514 5063.751232425661 5513.201639494252 7220.94835747767 5916.165881520971 7711.710982797232 0.8832399609178528 0.9686711997854807 0.8614975327927132 1.0832596840604336 1.1552499255118625 0.6566313550548689 0.71491289699429 0.936361382524018 0.767166442663419 1.0 12.912835268348934 -6.765249649445721 24.999998518468143 0.8047806816912566 0.9871768439731895 0.33529136823299155 0.12299778820893391 118.77303898093717 779289.7462786346 0.04373860071270717 0.04003150567957847 1.7169211500382763e-07 6.765249649445721 0.1823961622819329 RPS(ph)VASSVSEEYFEVR ddPTM_PC-9_Lapatinib_30min_R1 2 RPSVASSVSEEYFEVR 16 1 A6ND36;A6ND36-2;K7EKG0 A6ND36 FAM83G Protein FAM83G 1 RPS(0.969)VAS(0.024)S(0.007)VSEEYFEVR;RPS(0.995)VAS(0.004)S(0.001)VSEEYFEVR 90.01700000000001 0.0016567999999999997 4497100.0 20161.2 16383.5 17922.1 13924.2 14933.8 16035.7 16040.7 15714.3 20436.9 11873.099999999999 True False 19873.697590888736 16345.565012349249 16448.61411930663 14948.23211776954 14055.423244980457 15349.890492042448 16871.208958252104 16444.443745872584 18135.08111190232 13925.349515088707 1.4271596967354208 1.1737992640427544 1.1811993732353976 1.073454716635478 1.009340787443131 1.1022984001521967 1.2115465353290726 1.1808998925344267 1.3023070690076533 1.0 13.76542591805602 -4.5717182198467015 1.9852486920469343 1.1338786221058896 1.6646100792939285 0.49956155058225216 0.08781449219355227 1.4416582310057033 3.71943192133844 0.024694240947043353 1.7003749910369892 2.6809071943090005e-05 4.5717182198467015 0.5307314571880388 RPS(ph)VGSQSNQAGQGK ddPTM_PC-9_AZD4547_30min_R2 3 RPSVGSQSNQAGQGK 15 1 Q9UPP1-4;Q9UPP1-3;Q9UPP1-2;Q9UPP1;H0Y3N9 Q9UPP1-4 PHF8 Histone lysine demethylase PHF8 1 RPS(0.922)VGS(0.078)QSNQAGQGK;RPS(0.998)VGS(0.002)QSNQAGQGK;RPS(0.911)VGS(0.089)QSNQAGQGK 117.29 5.9991e-05 71406900.0 49707.6 51130.0 57872.0 85419.0 66944.0 63042.0 48885.0 66146.0 54031.0 56526.0 True False 65513.58281769054 67656.77259835441 57104.579467106945 65726.9692603944 57649.98113755304 59099.973774132945 53235.67029720657 55924.655583866996 56886.96835352728 54547.04194517538 1.2010473983820702 1.2403380675776237 1.0468868233863555 1.204959369317512 1.056885563024598 1.083467987751447 0.9759588861062923 1.0252555150483915 1.0428974024055004 1.0 15.735213341694335 -5.757329027921205 0.4854626430374169 1.0011684597879669 1.2680195566696397 0.650796983830483 0.05239450137629705 1.2038142933358416 0.42360611428614536 0.03950809561549104 0.1675515614124672 1.7485214809610138e-06 5.757329027921205 0.26685109688167286 RPS(ph)VGSQSNQAGQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RPSVGSQSNQAGQGK 15 1 Q9UPP1-4;Q9UPP1-3;Q9UPP1-2;Q9UPP1;H0Y3N9 Q9UPP1-4 PHF8 Histone lysine demethylase PHF8 1 RPS(0.973)VGS(0.026)QS(0.001)NQAGQGK;RPS(0.961)VGS(0.038)QS(0.001)NQAGQGK;RPS(0.722)VGS(0.203)QS(0.075)NQAGQGK;RPS(0.957)VGS(0.043)QSNQAGQGK 102.47 0.00067581 33114700.0 58234.0 51598.0 52252.0 60551.0 83747.0 87417.0 108608.0 97703.0 82657.0 72590.0 True False 68091.86602607233 56720.30844069773 53497.88584681349 57158.523778990704 67337.37653286986 82832.69863116648 98319.86398617299 95138.39977488549 83865.70225331912 85749.99237787601 0.7940743099545793 0.6614613817193982 0.623882106147175 0.6665717651275026 0.7852755978814908 0.965979078646983 1.1465874370332898 1.1094858102801621 0.9780257691889539 1.0 16.387848922596987 -6.748330086802286 2.3588414230285593 1.067490113061117 0.6823671515189283 0.8811584697691807 0.06261699317861937 0.09171495062291779 1.0471539504262128 0.024555402878030666 0.022873565930640594 1.7851302655788406e-07 6.748330086802286 -0.3851229615421886 RPS(ph)VGSQSNQAGQGK ddPTM_PC-9_Lapatinib_30min_R1 5 RPSVGSQSNQAGQGK 15 1 Q9UPP1-4;Q9UPP1-3;Q9UPP1-2;Q9UPP1;H0Y3N9 Q9UPP1-4 PHF8 Histone lysine demethylase PHF8 1 RPS(0.961)VGS(0.036)QS(0.003)NQAGQGK;RPS(0.996)VGS(0.004)QSNQAGQGK;RPS(0.88)VGS(0.09)QS(0.03)NQAGQGK;RPS(0.986)VGS(0.013)QSNQAGQGK;RPS(0.987)VGS(0.013)QSNQAGQGK 131.9 3.7622e-06 50731300.0 55413.399999999994 44171.6 64637.1 43756.200000000004 72749.0 99072.0 96203.0 87722.0 105817.0 90235.0 True False 54623.19475442697 44069.32337409504 59322.887144421424 46974.17691440423 68470.04685003702 94834.92150811202 101183.92061510577 91797.88436490537 93898.77515759085 105831.9995194201 0.516131179628744 0.4164083034829966 0.5605382815576088 0.44385608443299324 0.6469692263300082 0.8960892918848223 0.9560805906963762 0.867392516268773 0.8872437030764073 1.0 16.691416383249177 -6.6213812637582725 2.6587024851207866 0.9199937987047693 0.4855187692348418 0.9433049340533209 0.05082211132072792 0.05809751738166964 0.8331696098879274 0.017721718603382383 0.017832875679249554 2.391215605048076e-07 6.6213812637582725 -0.4344750294699275 RPS(ph)VNGEPGSVPPPR ddPTM_PC-9_AZD4547_30min_R2 4 RPSVNGEPGSVPPPR 15 1 Q8N3D4 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 RPS(1)VNGEPGSVPPPR;RPS(0.991)VNGEPGS(0.009)VPPPR;RPS(0.993)VNGEPGS(0.007)VPPPR;RPS(1)VNGEPGSVPPPR 128.82 2.4803000000000003e-05 55401800.0 35086.9 41629.3 61924.3 92198.7 72844.2 63184.7 42888.9 76782.9 49720.9 54207.9 True False 46243.80434714258 55085.157119668904 61103.14332138118 70943.7141707152 62731.04021241851 59233.75072057451 46705.929013191446 64917.86710051253 52349.04526677083 52310.097920600616 0.884032073832746 1.0530501625762665 1.168094607930713 1.3562145167152584 1.199214734937706 1.1323578634947888 0.8928664038076259 1.241019796962505 1.0007445473764804 1.0 15.674801850185368 -7.033908196096014 24.80596314357001 1.0478668741340824 1.144537566331301 0.10233155459327092 0.13799625490779083 1526.7103424206823 1116879.9431224193 0.055778019261001295 0.04323159200597916 9.248936631257044e-08 7.033908196096014 0.09667069219721869 RPS(ph)VNGEPGSVPPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RPSVNGEPGSVPPPR 15 1 Q8N3D4 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 RPS(1)VNGEPGSVPPPR;RPS(0.998)VNGEPGS(0.002)VPPPR;RPS(1)VNGEPGSVPPPR;RPS(1)VNGEPGSVPPPR 130.47 1.0352e-05 48046700.0 68271.5 75716.7 76780.6 60894.1 80706.8 69037.3 64133.2 67687.09999999999 59805.0 53779.2 True False 79828.51652641036 83233.35358176235 78611.34069604691 57482.4009983359 64892.88189861142 65416.862454779184 58058.039011840934 65910.38534541064 60679.53498505578 63528.94324408703 1.2565692493844594 1.3101643019933171 1.2374098589049596 0.9048222442089194 1.0214695630821993 1.0297174659971677 0.9138832797639004 1.0374859391596327 0.9551478725518316 1.0 15.955126400747098 -5.684136987235517 5.917557309362711 0.9832780040021738 1.278973547253593 0.8931777797926425 0.04566180241914225 0.05659503431537983 3.2845987432849797 0.01196566572259295 0.020839156077619467 2.069488477910854e-06 5.684136987235517 0.2956955432514192 RPS(ph)VNGEPGSVPPPR ddPTM_PC-9_Lapatinib_30min_R1 4 RPSVNGEPGSVPPPR 15 1 Q8N3D4 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 RPS(0.999)VNGEPGS(0.001)VPPPR;RPS(1)VNGEPGSVPPPR;RPS(0.998)VNGEPGS(0.002)VPPPR;RPS(0.986)VNGEPGS(0.014)VPPPR 132.25 1.0589000000000001e-05 45306300.0 36607.8 34474.1 56142.4 41694.9 46777.9 44567.3 42216.5 43239.799999999996 62067.1 37394.6 True False 36085.766058951696 34394.27733953239 51526.588587931175 44761.28203610899 44026.515890889896 42661.26047045057 44402.263803079084 45248.87896265062 55076.44960246182 43858.20678482755 0.8227825235991026 0.7842153125018066 1.174844854937308 1.0205907928637397 1.0038375738180105 0.9727087265503283 1.0124049079553281 1.0317083683937613 1.255784347788591 1.0 15.420559205798895 -5.2460120723794335 24.971371944073493 1.0520317528410374 0.803498867583578 0.5922506063093096 0.08463798950163418 558.9436708325418 904729.2828208976 0.021722601225782016 0.0570305518824623 5.675288292039698e-06 5.2460120723794335 -0.24853288525745942 RPS(ph)VYLPTR ddPTM_PC-9_AZD4547_30min_R2 3 RPSVYLPTR 9 1 Q9BW61 Q9BW61 DDA1 DET1- and DDB1-associated protein 1 1 RPS(1)VYLPTR;RPS(1)VYLPTR;RPS(1)VYLPTR 64.827 0.024197 29273600.0 39248.0 37626.0 44772.0 59310.0 50880.0 42980.0 34873.5 51291.0 43340.0 40907.0 True False 51728.04759088582 49787.86868346723 44178.294026494885 45636.99583036555 43816.19025272918 40292.45380559363 37977.17394107871 43365.154499926284 45630.863919636366 39474.85838112173 1.31040489345046 1.2612551564536467 1.1191501588165924 1.1561028386663135 1.1099771360720987 1.020711801333856 0.9620597894086615 1.0985512368719486 1.155947501548445 1.0 15.268646469872584 -5.019467733951474 0.7294377874450716 1.0522242402935338 1.4286257071975923 0.7094370028379215 0.05616458885181805 1.2962318671239972 0.6547176372412528 0.02614657983583952 0.37956412652649907 9.561637308735648e-06 5.019467733951474 0.3764014669040585 RPS(ph)VYLPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPSVYLPTR 9 1 Q9BW61 Q9BW61 DDA1 DET1- and DDB1-associated protein 1 1 RPS(1)VYLPTR;RPS(1)VYLPTR 81.23899999999999 0.0080321 20376500.0 23752.0 25703.0 26662.0 24330.0 23472.0 22130.0 21587.6 28354.0 20743.2 16813.6 True False 27772.744476616215 28254.62397479076 27297.723196198076 22966.868978924256 18872.830095161826 20969.463842361518 19542.66624731058 27609.737543546296 21046.530057721073 19861.772583615628 1.3983014033463712 1.4225630595578647 1.3743850445008374 1.1563353110723906 0.9502087497835112 1.0557700101580887 0.983933642631258 1.3900943345974124 1.0596501379279095 1.0 14.277706762912924 -5.797644526527896 3.5679296111379095 1.0850226150708888 1.407725272498903 0.6171414229900118 0.11451712815373905 0.1601030445604577 4.231501010422165 0.03435557067836042 0.05670639799138445 1.5935124960009013e-06 5.797644526527896 0.3227026574280141 RPS(ph)VYLPTR ddPTM_PC-9_Lapatinib_30min_R1 2 RPSVYLPTR 9 1 Q9BW61 Q9BW61 DDA1 DET1- and DDB1-associated protein 1 1 RPS(1)VYLPTR;RPS(1)VYLPTR 68.46300000000001 0.019707 19603800.0 22371.1 29057.0 25988.6 29469.9 26723.5 21907.1 28916.0 27668.7 30703.0 29463.0 True False 22052.084011642717 28989.720301756744 23851.9176268971 31637.21475470451 25151.676270422467 20970.184400944345 30413.128992925373 28954.288811555354 27244.90482307673 34555.64029302022 0.6381616380031871 0.8389287553618934 0.6902467274413339 0.9155441625862395 0.7278602293907653 0.6068527228297386 0.8801205457352912 0.8379034092852199 0.7884358267434518 1.0 15.076633591136652 -14.522878732830723 0.1736616876267035 1.9273536430391003 0.7204154996512044 0.3795272720139973 0.09420398275239389 147.58427316084925 1.3988843798369182 46.87637352188032 0.32164536744811134 3.0000000859988938e-15 14.522878732830723 -1.2069381433878958 RPS(ph)YLEWQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPSYLEWQAR 10 1 E9PIY0;A0A3B3IU03;Q96KS9 E9PIY0 FAM167A Protein FAM167A 1 RPS(0.997)Y(0.003)LEWQAR 66.00399999999999 0.021699 2163900.0 10418.0 9107.4 8566.9 9511.6 13626.0 12230.0 11433.0 9955.3 11169.0 9948.2 True False 12181.56163512073 10011.522483290253 8771.167386149176 8978.695889023262 10956.083115059444 11588.637270315465 10349.983472248034 9693.983923512253 11332.325495327945 11751.729910092132 1.0365760384485578 0.8519190416972205 0.7463724450148133 0.7640318453296439 0.9322953470578486 0.9861218185727186 0.8807199919868556 0.8248984615607332 0.9643112615782625 1.0 13.520585523489535 -6.306364111860738 24.930059342246825 0.922839069858645 0.8424991884900618 0.16759043175210575 0.08734202723398611 843.3502627489308 467997.5263975714 0.028629422179017965 0.03246282727868477 4.938964313071605e-07 6.306364111860738 -0.08033988136858317 RPS(ph)YTLGMK ddPTM_PC-9_AZD4547_30min_R2 3 RPSYTLGMK 9 1 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 RPS(0.95)YT(0.05)LGMK;RPS(0.885)Y(0.015)T(0.1)LGMK;RPS(0.568)Y(0.091)T(0.341)LGMK 71.085 0.016471 65778000.0 352960.0 305954.0 366130.0 504040.0 519850.0 420880.0 342312.0 502390.0 404050.0 434850.0 True False 465193.9379759244 404847.64724343584 361274.87697490765 387841.365340372 447677.8007641763 394562.3070660369 372777.1048537871 424757.16927371174 425407.258115576 419626.03385803854 1.108591699373213 0.9647820072583907 0.8609448600062994 0.9242547746014743 1.0668494436539842 0.9402712778290567 0.8883555231940146 1.0122278767322836 1.0137770867178686 1.0 18.678744660819042 RPS(ph)YTLGMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPSYTLGMK 9 1 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 RPS(0.937)Y(0.008)T(0.054)LGMK 50.354 0.043157999999999995 39187000.0 173530.0 176520.0 171180.0 164370.0 202120.0 133120.0 130390.0 163720.0 128600.0 114880.0 True False 202905.20162627185 194043.73901996145 175261.58040376505 155160.88179473017 162516.0369305599 126138.95285563341 118038.5152581494 159422.52347567852 130480.53171270234 135706.83461042048 1.4951730486438701 1.4298744759393383 1.2914720242859994 1.1433534813493902 1.1975523369703653 0.9294959477740822 0.86980523565381 1.1747567757610713 0.9614882852973359 1.0 17.050133855549213 -5.626356653280772 0.8470693548697077 0.9956838907851724 1.5487246904624474 0.8106526191759953 0.08763193049732866 0.39734084553029475 0.47289736366621427 0.03909276095068111 0.16432123504772417 2.3639775437809577e-06 5.626356653280772 0.553040799677275 RPS(ph)YTLGMK ddPTM_PC-9_Lapatinib_30min_R1 2 RPSYTLGMK 9 1 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 RPS(0.822)Y(0.001)T(0.177)LGMK;RPS(0.969)Y(0.001)T(0.03)LGMK 76.52199999999999 0.011182 38946000.0 335530.0 266960.0 299450.0 288340.0 280620.0 250780.0 217080.0 200352.0 300290.0 273330.0 True False 330745.2806713346 266341.87052197393 274830.3769104279 309545.4854740427 264114.4833201475 240054.7239967326 228319.34021940248 209661.0853409356 266468.178006114 320574.72631066764 1.0317260018520946 0.8308261652038755 0.8573051908156069 0.9655954137010273 0.8238780591336924 0.7488261060358719 0.7122187792126169 0.6540162655796948 0.8312201684542054 1.0 18.290301164235125 -6.496132731977353 4.413539230077373 0.7640324959645463 0.9099380883160533 0.25737121849778666 0.1011512492034693 0.25199899912527307 11.661707078214135 0.03190355788111539 0.0346045483619488 3.190562585048079e-07 6.496132731977353 0.14590559235150702 RPSADS(ph)ESPGTPSPDGAAWEPPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPSADSESPGTPSPDGAAWEPPAR 24 1 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 RPS(0.091)ADS(0.456)ES(0.335)PGT(0.118)PSPDGAAWEPPAR 76.762 0.00010812 9423800.0 3097.6 3878.8 1443.9 3135.3 3667.4 2403.3 4068.2 2402.6 3083.0 3075.7 True False 3621.9624996112493 4263.861629903836 1478.328052021243 2959.6393057797477 2948.799296651182 2277.266717232146 3682.8306447826003 2339.5342957651233 3128.083042537026 3633.300062772196 0.9968795411980655 1.1735506443832011 0.4068830062148194 0.8145870846465548 0.8116035685754118 0.6267763955324404 1.0136323951104145 0.6439144181171941 0.8609481706694792 1.0 11.827064802960772 -5.218077157096491 24.999809906362692 0.7659122005230793 1.085215251470252 0.33641078056608886 0.17561375555397687 490.47453953093685 282773.82817476353 0.041892336912518605 0.11083524474978053 6.052333389745472e-06 5.218077157096491 0.3193030509471727 RPSADS(ph)ESPGTPSPDGAAWEPPAR ddPTM_PC-9_Lapatinib_30min_R1 1 RPSADSESPGTPSPDGAAWEPPAR 24 1 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 RPS(0.117)ADS(0.498)ES(0.385)PGTPSPDGAAWEPPAR 109.2 3.8324e-07 10381000.0 4111.0 2159.2 6708.1 4273.1 5899.5 4857.3 3441.6 3342.5 4702.5 5618.7 True False 4052.3763861349335 2154.200505060853 6156.585912014825 4587.358028643728 5552.503008863264 4649.564601919334 3619.7892081218683 3497.804752396167 4172.854930479702 6589.884808552859 0.6149388803997679 0.3268950167785886 0.9342478800273314 0.6961211253176842 0.8425796763028086 0.7055608310307293 0.5492947620911108 0.5307838989623077 0.6332212249087951 1.0 12.686037531749434 -11.7984038695204 2.1567973594386203 2.376895978484306 0.6496003789887285 0.30537795692594294 0.15916908980469321 6653992.30885415 1019490.6416841864 44617859.05693334 0.04445799644073066 1.5907287504530033e-12 11.7984038695204 -1.7272955994955774 RPSADSES(ph)PGTPSPDGAAWEPPAR ddPTM_PC-9_AZD4547_30min_R2 2 RPSADSESPGTPSPDGAAWEPPAR 24 1 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 RPS(0.239)ADS(0.239)ES(0.522)PGTPSPDGAAWEPPAR;RPS(0.064)ADS(0.417)ES(0.519)PGTPSPDGAAWEPPAR 120.29 4.584399999999999e-09 21990000.0 5525.3 3165.7 8035.7 13389.1 11841.1 4526.299999999999 9201.5 12919.400000000001 4776.2 6691.7 True False 7282.23046662051 4188.950616362415 7929.1413675668955 10302.449854532913 10197.167657263974 4243.269745469017 10020.415674332542 10923.003588277626 5028.660181194446 6457.425619794958 1.1277296705202686 0.6487028830067153 1.2279106000478668 1.5954422801172035 1.579138229018852 0.6571147691521925 1.5517663329509197 1.6915415262072293 0.7787407052400737 1.0 12.656743405340482 -5.41866611044843 6.959886284262097 1.302027888785894 0.8925300469327418 0.14305371133509115 0.356799185146912 0.4183720286119827 24.259765842430003 0.09256227055566608 0.19401371346879054 3.813589029147454e-06 5.41866611044843 -0.4094978418531522 RPSADSES(ph)PGTPSPDGAAWEPPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPSADSESPGTPSPDGAAWEPPAR 24 1 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 RPS(0.005)ADS(0.031)ES(0.96)PGT(0.004)PSPDGAAWEPPAR 78.025 9.1032e-05 8636900.0 5036.5 1819.5 2111.8 6213.0 5014.8 2172.4 2849.4 5238.9 1992.0 1473.0 True False 5889.079974590665 2000.1279353434124 2162.153321046098 5864.905752817775 4032.185939043014 2058.475519708365 2579.48420413046 5101.384426073384 2021.1292315062474 1740.0432397384147 3.384444616144129 1.1494702485922688 1.2425859723871806 3.370551730484273 2.3172906551731343 1.183002509763965 1.482425347382885 2.9317572745147924 1.1615396591007066 1.0 10.764907441874646 -6.730685976370689 24.974601936096914 1.668146968555946 2.23086902274894 0.14888144632314526 0.8574875776963228 534.6220284718061 434161.08792604285 0.2889937738390119 0.2889636834509251 1.8591482563350953e-07 6.730685976370689 0.5627220541929938 RPSADSES(ph)PGTPSPDGAAWEPPAR ddPTM_PC-9_Lapatinib_30min_R1 1 RPSADSESPGTPSPDGAAWEPPAR 24 1 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 RPS(0.049)ADS(0.088)ES(0.863)PGTPSPDGAAWEPPAR 135.08 1.3726e-07 10960000.0 7060.5 7129.3 6252.6 6176.3 7125.5 6927.4 6534.8 5001.8 5026.5 8212.2 True False 6959.815975262877 7112.79254387289 5738.535363733977 6630.525705532811 6706.392099272001 6631.131250558125 6873.139968978029 5234.201887968631 4460.362638608445 9631.66782793133 0.7225971762730207 0.7384798428415654 0.5957987200402122 0.6884088845240941 0.6962856505312421 0.6884717547389035 0.7135981111232144 0.5434367112193925 0.46309348684904067 1.0 13.233569922683737 RPSAGGGLQR ddPTM_PC-9_AZD4547_30min_R2 1 RPSAGGGLQR 10 1 Q9H6K5;Q9H6K5-2 Q9H6K5 PRR36 Proline-rich protein 36 0 65.627 0.030574 7269400.0 11494.0 11032.0 20205.0 20214.0 20141.0 16931.0 10284.0 17190.0 12537.0 14040.0 False True 15148.852909948073 14597.878257481816 19937.06849828753 15553.974603186796 17344.769808966557 15872.301893497115 11199.256077252176 14533.680486902835 13199.68022520723 13548.463873443401 1.118123283307536 1.0774563370313437 1.47153719303681 1.1480249531221347 1.2802019454740081 1.1715204056903243 0.8266070738251033 1.0727179570069618 0.974256590895162 1.0 13.725841667453688 -7.091332211767767 6.692780842190028 0.9754552973302347 1.221771315317718 0.5141000660088036 0.11624443515578876 0.2115846581489686 13.138888565494218 0.04447639216755134 0.034471932626847245 8.103409537498982e-08 7.091332211767767 0.24631601798748337 RPSAS(ph)SPNNNTAAK ddPTM_PC-9_AZD4547_30min_R2 1 RPSASSPNNNTAAK 14 1 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 RPS(0.002)AS(0.867)S(0.131)PNNNTAAK 131.24 2.495e-05 2999700.0 2263.5 4721.0 2710.2 4864.5 4549.5 2988.2 3633.0 4073.4 2531.5 4692.2 True False 2983.2459162752257 6246.970925813237 2674.2609771867787 3743.0646807758058 3917.8804550863074 2801.3473816164474 3956.329961946437 3443.949627420013 2665.309921840319 4527.927506194524 0.6588546111204155 1.3796534766219073 0.5906147952961264 0.8266617951932821 0.8652701373258231 0.6186820300863931 0.8737617721427516 0.7606017593498233 0.5886379404692296 1.0 12.144635144931952 -5.294110746358199 24.999934804182644 0.7613453072982393 1.0192547168702366 0.19532231286839818 0.20585575586942373 814.9482022872643 623592.0814296849 0.049443896910179 0.10293708209864841 5.080298769426959e-06 5.294110746358199 0.25790940957199726 RPSAS(ph)SPNNNTAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPSASSPNNNTAAK 14 1 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 RPS(0.377)AS(0.496)S(0.127)PNNNTAAK 128.99 1.0986e-05 3373700.0 12776.0 13858.0 16927.0 16956.0 25150.0 24214.0 28232.0 23673.0 25458.0 21025.0 True False 14938.724462497838 15233.730655668596 17330.603876004974 16006.010292093712 20222.038040785625 22944.175213689185 25557.660578020328 23051.60883361682 25830.275088195784 24836.666066191578 0.6014786534829198 0.6133565034481505 0.6977830208699354 0.6444508393129937 0.8142009876403047 0.9238025406687531 1.0290294401795814 0.9281281461925105 1.0400057326275662 1.0 14.600183906868667 -6.548347998334536 1.4453885059441485 0.9975746412884595 0.6283144088508785 0.9502254376550886 0.03748865997367038 0.07884161326352236 0.33912014597720724 0.01520525440820192 0.016496844188279732 2.8291241220888896e-07 6.548347998334536 -0.369260232437581 RPSAS(ph)SPNNNTAAK ddPTM_PC-9_Lapatinib_30min_R1 1 RPSASSPNNNTAAK 14 1 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 RPS(0.22)AS(0.655)S(0.125)PNNNTAAK 94.61 0.0015600999999999998 3485700.0 17949.0 13951.0 17945.0 15335.0 11831.0 11748.0 9629.4 10649.0 13003.0 8226.1 True False 17693.043968556536 13918.697316646892 16469.631369703195 16462.787056060362 11135.123840640941 11245.565425925577 10127.963214983938 11143.791416085802 11538.46521233972 9647.970424410745 1.8338617543634466 1.4426554709818138 1.707056577208474 1.7063471727076565 1.1541415811627578 1.1655887125724067 1.0497506490441495 1.1550399644561944 1.195947407046953 1.0 13.236009769364705 -6.2718855131251665 11.937295743622501 1.1265257372138473 1.65855847761452 0.867393956462718 0.10573786654526893 0.23923771036480537 271.7599221071371 0.03126178114926684 0.036557040915026054 5.347052975688486e-07 6.2718855131251665 0.5320327404006726 RPSASS(ph)PNNNTAAK ddPTM_PC-9_AZD4547_30min_R2 4 RPSASSPNNNTAAK 14 1 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 RPS(0.018)AS(0.045)S(0.938)PNNNTAAK;RPS(0.001)AS(0.062)S(0.935)PNNNT(0.001)AAK;RPS(0.157)AS(0.129)S(0.715)PNNNTAAK;RPS(0.004)AS(0.24)S(0.753)PNNNT(0.003)AAK 110.6 0.00070459 22602100.0 32143.300000000003 36687.520000000004 65408.9 85822.3 76785.0 57878.2 47098.0 79838.9 41595.7 70575.8 True False 42364.200777826154 48546.04337644389 64541.53524858397 66037.29467631734 66124.72815557799 54259.06700444178 51289.63075908431 67501.63252040657 43794.363782695415 68104.96272360181 0.6220427863643014 0.7128121275605696 0.9476774183185488 0.9696399797519025 0.9709237845697026 0.7966976977088671 0.7530968186156846 0.9911411712294181 0.6430421812347378 1.0 16.055472309003598 -5.0844265543193705 4.1857928612879824 0.8814886767218049 0.6381321693960819 0.3805833083424829 0.11292784381283898 0.21673315156826092 6.748081608163986 0.028783029450574996 0.09153835569153908 8.233290623847395e-06 5.0844265543193705 -0.243356507325723 RPSASS(ph)PNNNTAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPSASSPNNNTAAK 14 1 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 RPS(0.007)AS(0.007)S(0.986)PNNNTAAK;RPS(0.014)AS(0.016)S(0.97)PNNNT(0.001)AAK 91.31700000000001 0.0021024999999999998 19621900.0 28383.6 31759.0 35812.0 37388.0 45473.0 30008.0 26216.0 25810.5 27469.6 21649.1 True False 33188.382878346405 34911.82363208107 36665.893897766306 35293.271573531456 36562.892080661804 28434.327653935117 23732.6306925964 25133.00172348529 27871.290932622484 25573.910455818692 1.2977437664717886 1.3651343501962474 1.4337226198203066 1.3800498611467287 1.42969500670723 1.111849034705039 0.9280016340714389 0.9827594323873499 1.0898329757106457 1.0 14.642385156627748 -6.888713515543346 4.051842461177824 1.0006439179882232 1.3828812056619963 0.9232088996813216 0.05240832176292983 0.057389284867260554 1.7270525898255489 0.01978952620621188 0.01735214798758841 1.2920713136511974e-07 6.888713515543346 0.3822372876737732 RPSASS(ph)PNNNTAAK ddPTM_PC-9_Lapatinib_30min_R1 2 RPSASSPNNNTAAK 14 1 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 RPS(0.189)AS(0.132)S(0.679)PNNNTAAK;RPS(0.002)AS(0.025)S(0.973)PNNNTAAK 88.264 0.0026519 22252900.0 41867.0 39057.0 47267.0 29755.0 30034.0 28093.0 24008.0 23724.0 32030.0 18714.2 True False 41269.9689025325 38966.56591615495 43380.88971589641 31943.28195977024 28267.459169115893 26891.52787798154 25251.016767953814 24826.303648720008 28422.44410914721 21948.924534895956 1.8802729417069424 1.7753291672310934 1.9764471670093173 1.455346110875936 1.2878744525352157 1.2251865842095127 1.1504443749764577 1.1310943098487305 1.2949356158184058 1.0 14.421862631101249 -6.018065671889948 2.157349800800794 1.1800061654692466 1.8727592026370863 0.9098826073906102 0.09739100208497442 0.08214387403479927 0.7648184753760577 0.029721886316675737 0.045807456273386504 9.592555666075567e-07 6.018065671889948 0.6927530371678396 RPSGTGTGPEDGRPS(ph)LGSPYGQPPR ddPTM_PC-9_AZD4547_30min_R2 2 RPSGTGTGPEDGRPSLGSPYGQPPR 25 2 P50479;P50479-2;C9J542 P50479 PDLIM4 PDZ and LIM domain protein 4 1 RPSGTGTGPEDGRPS(0.712)LGS(0.269)PY(0.018)GQPPR;RPS(0.128)GT(0.128)GT(0.1)GPEDGRPS(0.53)LGS(0.105)PY(0.009)GQPPR 79.455 0.00091932 11540000.0 16878.8 25333.9 17387.6 28463.4 23363.2 28548.7 26766.8 27871.4 26336.0 23150.1 True False 22245.90729915012 33522.58774358397 17157.029063143993 21901.602885146283 20119.622958187152 26763.545275936485 29148.993345837556 23564.515551056655 27728.0671939904 22339.62204534203 0.9958049985804729 1.5005888495133997 0.768008922815297 0.9803927228801494 0.9006250382101804 1.1980303526002078 1.3048113923626263 1.0548305384589094 1.2412057436652963 1.0 14.447317157227287 -6.802963710147828 24.998551402573828 1.17226736880865 1.0380692027127185 0.09912563983821332 0.19424531045756765 373.53251277846806 224872.15622090752 0.06954689429145393 0.06133511995525347 1.5741143927135043e-07 6.802963710147828 -0.1341981660959315 RPSGTGTGPEDGRPSLGS(ph)PYGQPPR ddPTM_PC-9_Lapatinib_30min_R1 1 RPSGTGTGPEDGRPSLGSPYGQPPR 25 2 P50479;P50479-2;C9J542 P50479 PDLIM4 PDZ and LIM domain protein 4 1 RPSGTGTGPEDGRPS(0.03)LGS(0.773)PY(0.196)GQPPR 48.788000000000004 0.010054 15432000.0 8159.4 11362.0 11724.0 8682.5 16088.0 19659.0 18436.0 22240.0 17011.0 11505.0 True False 8043.0454597492935 11335.691987079195 10760.09797594874 9321.040013970929 15141.735470224961 18818.230397367297 19390.52587195919 23273.351591111677 15095.042046228646 13493.62392055112 0.5960626668644247 0.8400776584424188 0.7974209181538584 0.6907736623498716 1.1221400240126544 1.3946016658065201 1.4370139546002128 1.7247665807304584 1.1186796175072382 1.0 13.719990237849444 -6.472911426524429 2.7792974781305886 1.3863528280230153 0.7421113172018168 0.6768907646722948 0.19479052338255531 0.14905690355191129 2.2864433191355897 0.06466546286808908 0.07123526737186199 3.3658020722412716e-07 6.472911426524429 -0.6442415108211985 RPSQEQS(ph)ASASSGQPQAPLNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPSQEQSASASSGQPQAPLNR 21 1 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 1 RPS(0.014)QEQS(0.662)AS(0.303)AS(0.02)S(0.001)GQPQAPLNR 67.396 0.0016925 18847000.0 16367.0 18168.0 18484.0 18175.0 25559.0 21067.0 18833.0 18813.0 17337.0 17750.0 True False 19137.609837014883 19971.598971870928 18924.72866096037 17156.71367414503 20550.897426816697 19962.20943366607 17049.00190088754 18319.178684021175 17590.52082661838 20967.9344910773 0.9127083950571625 0.9524828962227847 0.9025556937433967 0.8182357533330669 0.9801107226637861 0.9520350915900082 0.8130987774757965 0.8736758831355909 0.8389248275314793 1.0 14.355897131005566 -7.241854101432759 24.960406767904455 0.8708978494209898 0.9185350299569532 0.07558777523220872 0.06119935008165923 1749.5600748420306 2229724.045055147 0.023095647220192767 0.017863803646219287 5.72988490624926e-08 7.241854101432759 0.04763718053596344 RPSQGPPAR ddPTM_PC-9_AZD4547_30min_R2 1 RPSQGPPAR 9 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 0 120.31 0.0010662 2245300.0 3545.0 4915.5 5765.8 7565.0 5824.4 4623.2 4275.1 6361.5 4407.9 6370.3 False True 4672.23625941934 6504.339247158436 5689.341724693203 5821.006128084897 5015.782596462181 4334.110573150778 4655.575618033917 5378.476347727305 4640.892595093798 6147.277735968412 0.7600496447527596 1.0580844930920912 0.9255058855408835 0.9469242123266265 0.8159355753709114 0.7050455110871939 0.757339397696906 0.8749362854157762 0.7549508570174753 1.0 12.585731952626913 -6.294796183862081 6.428276487055208 0.8025771575105545 0.9326007211554144 0.19060060594488448 0.10195422495207147 0.2650671126759456 35.93949525162078 0.03026865219508518 0.034997929673892134 5.072286968826436e-07 6.294796183862081 0.1300235636448599 RPSS(ph)TSVPLGDK ddPTM_PC-9_Lapatinib_30min_R1 1 RPSSTSVPLGDK 12 1 Q9NXR1;Q9NXR1-1;I3L533;I3L2R9;I3L2T8 Q9NXR1 NDE1 Nuclear distribution protein nudE homolog 1 1 RPS(0.104)S(0.895)T(0.001)SVPLGDK 169.98 0.0015239000000000001 21545000.0 62896.0 87195.0 95010.0 88435.0 67945.0 82111.0 66711.0 63840.0 74445.0 92817.0 True False 61999.0915062862 86993.10533474469 87198.644549206 94938.80491051177 63948.60868500965 78599.3039400898 70164.9691605701 66806.23945937812 66060.22015939633 108860.2947791218 0.5695289695116362 0.7991261231769969 0.8010142240210958 0.8721160006331342 0.5874374014397238 0.7220199439985742 0.6445414216720177 0.613687842706364 0.6068348454634714 1.0 16.732118322243004 -10.496540664271713 4.572990711857393 1.000005467265451 0.6967312729846993 0.46524757093605673 0.09929042994591386 36833205.43308564 1403.5254715430933 2382.5931985550264 0.025359766193162447 3.18756710042481e-11 10.496540664271713 -0.30327419428075175 RPSTSQT(ph)VSTPAPVPVIESTEAIEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPSTSQTVSTPAPVPVIESTEAIEAK 26 1 P12270;P12270-2 P12270 TPR Nucleoprotein TPR 1 RPS(0.071)T(0.071)S(0.071)QT(0.262)VS(0.262)T(0.262)PAPVPVIESTEAIEAK 51.81100000000001 0.012884 9271700.0 12585.0 14543.0 10435.0 9849.3 12354.0 10733.0 11808.0 9412.1 8863.5 10486.0 True False 14715.391934919791 15986.73292866131 10683.809974957878 9297.475652861434 9933.322383931036 10170.142585633352 10689.460757483146 9165.042347944276 8993.111919405432 12387.028792869678 1.1879678477368507 1.290602709978661 0.8624998095675518 0.7505815808076044 0.8019132392466009 0.8210316417030993 0.8629559950354115 0.7398902917881269 0.7260104153937319 1.0 13.596542557355153 -5.3154798805400425 5.0647066014670505 0.8066317922158873 1.240290215075615 0.8194626503811098 0.07859742611858532 0.06686244922129732 3.7801107809726355 0.019730410218230496 0.043786826274824116 4.836376691534415e-06 5.3154798805400425 0.43365842285972767 RPSTSQTVS(ph)TPAPVPVIESTEAIEAK ddPTM_PC-9_AZD4547_30min_R2 1 RPSTSQTVSTPAPVPVIESTEAIEAK 26 1 P12270;P12270-2 P12270 TPR Nucleoprotein TPR 1 RPS(0.052)T(0.136)S(0.136)QT(0.076)VS(0.34)T(0.26)PAPVPVIESTEAIEAK 81.297 1.1483e-05 3274100.0 3585.6 4140.4 5514.9 6664.7 6330.2 5482.9 4911.9 4004.5 5957.3 5754.3 True False 4725.746214886878 5478.703330065052 5441.768822628354 5128.256383588555 5451.360997205705 5140.053396246841 5349.049584388855 3385.696539255519 6272.190715931002 5552.843708472605 0.8510497436973186 0.9866482144465135 0.9799967563151885 0.923536957426659 0.981724190956058 0.9256614567422593 0.9632991427846604 0.6097230026643063 1.1295456968041093 1.0 12.439011074759803 RPSTSQTVST(ph)PAPVPVIESTEAIEAK ddPTM_PC-9_AZD4547_30min_R2 2 RPSTSQTVSTPAPVPVIESTEAIEAK 26 1 P12270;P12270-2 P12270 TPR Nucleoprotein TPR 1 RPS(0.043)T(0.043)S(0.043)QT(0.022)VS(0.097)T(0.752)PAPVPVIESTEAIEAK;RPS(0.024)T(0.024)S(0.024)QT(0.012)VS(0.201)T(0.716)PAPVPVIESTEAIEAK 102.09 1.5422e-09 23605000.0 43324.0 52169.0 66862.0 76770.0 72331.0 83981.0 66435.0 92038.0 70171.0 80894.0 True False 57100.130804819055 69031.60902960192 65975.36619314531 59071.86258467647 62289.089173941735 78729.65479403359 72347.5862983516 77815.64192283679 73880.09580306418 78061.92568221732 0.7314722293332637 0.8843185512822608 0.8451670339484675 0.7567307886453174 0.7979445629808659 1.0085538385836719 0.9267973556388007 0.9968450207033948 0.9464293271962445 1.0 16.25233143210236 -6.755784393082958 24.999939830622058 0.9724699442946434 0.807395300665155 0.7782251986014198 0.04602458167144759 66.74373182475608 295064.96119707514 0.015330422978657578 0.014927144719411787 1.754751437729171e-07 6.755784393082958 -0.16507464362948843 RPSTSQTVST(ph)PAPVPVIESTEAIEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPSTSQTVSTPAPVPVIESTEAIEAK 26 1 P12270;P12270-2 P12270 TPR Nucleoprotein TPR 1 RPS(0.021)T(0.021)S(0.021)QT(0.015)VS(0.333)T(0.589)PAPVPVIESTEAIEAK;RPS(0.183)T(0.183)S(0.183)QT(0.138)VS(0.12)T(0.192)PAPVPVIESTEAIEAK 120.42 4.54e-12 11491600.0 18899.8 22341.4 23565.3 22794.6 22969.8 22062.5 22174.4 17830.4 18164.9 18155.6 True False 22099.162851934605 24559.30654283117 24127.18612389793 21517.492463090304 18469.03258008897 20905.503661188475 20073.880303246475 17362.37089287041 18430.527297885463 21447.06656034949 1.03040491760261 1.1451126182559377 1.1249643887664964 1.0032837079393886 0.8611449275880836 0.9747488591207977 0.9359732365617912 0.8095452515156218 0.8593495640079335 1.0 14.388492715001778 -5.994764104809342 3.548922996076826 0.9026999731616476 1.103458209688634 0.6760470029535137 0.060007691314838726 0.13317468008208946 3.6083990746856247 0.018374002559753053 0.026836360062561973 1.0121290618584313e-06 5.994764104809342 0.20075823652698643 RPSTSQTVST(ph)PAPVPVIESTEAIEAK ddPTM_PC-9_Lapatinib_30min_R1 2 RPSTSQTVSTPAPVPVIESTEAIEAK 26 1 P12270;P12270-2 P12270 TPR Nucleoprotein TPR 1 RPS(0.016)T(0.016)S(0.016)QT(0.012)VS(0.166)T(0.775)PAPVPVIESTEAIEAK;RPS(0.064)T(0.064)S(0.064)QT(0.039)VS(0.093)T(0.677)PAPVPVIESTEAIEAK 104.97 8.446000000000001e-10 12858700.0 29502.8 26998.0 31950.3 33121.0 24854.2 30634.7 27596.2 17220.4 26277.9 22638.5 True False 29082.084661849112 26935.487789752187 29323.4696657246 35556.82882841706 23392.32482123727 29324.525293973624 29024.996206756372 18020.522650160936 23318.206183445527 26551.53456109487 1.0953071128499734 1.01446067939214 1.104398301282795 1.3391628550357826 0.8810159264961397 1.104438058994222 1.0931570128261356 0.6786998547558845 0.8782244254014968 1.0 14.696507624371849 -7.737700928279573 24.982302017816046 0.8338466382078495 1.0899729931453537 0.4159229930497915 0.12867150122305096 194.39580816347606 204582.11783758644 0.0595125982480096 0.034335064705569754 1.829359549137691e-08 7.737700928279573 0.25612635493750413 RPSTSSASGQWS(ph)PTPEWVLSWK ddPTM_PC-9_AZD4547_30min_R2 1 RPSTSSASGQWSPTPEWVLSWK 22 1 Q8IV36-3;Q8IV36-2;Q8IV36 Q8IV36-3 HID1 Protein HID1 1 RPS(0.124)T(0.186)S(0.186)S(0.186)AS(0.082)GQWS(0.203)PT(0.031)PEWVLSWK 45.861999999999995 0.028836 17661000.0 2498.3 9652.5 8586.1 13619.0 17744.0 9281.6 8560.9 10574.0 9196.4 12963.0 True False 3292.7074321318332 12772.48186007462 8472.242703941925 10479.349961452504 15280.551883734786 8701.22008473704 9322.803515339181 8940.03126634733 9682.502929177295 12509.169315630112 0.26322350821629864 1.0210495627487832 0.6772825988817597 0.8377334814997377 1.2215480898992912 0.6955873619733433 0.7452775863933994 0.7146782524701164 0.7740324465093843 1.0 13.610698368572654 -4.7503293412590555 24.946156130171634 0.8423023551922063 0.263222225005155 0.5280114059622258 0.1672682703491415 399.7199336120966 897460.3451849271 0.04212791833354519 0.6263468873985217 1.776931387449493e-05 4.7503293412590555 -0.5790801301870513 RPT(ph)CT(ph)ESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPTCTESR 8 1 Q5HYA6;Q76N32-2;Q76N32 Q5HYA6 DKFZp686H16130;CEP68 Centrosomal protein of 68 kDa 2 RPT(1)CT(0.999)ES(0.001)R 76.17 0.038648 609480.0 0.0 0.0 14109.0 1084.5 4936.6 5364.1 2325.0 1995.0 2524.0 1980.2 True False 0.0 0.0 14445.412068680467 1023.7389809964386 3969.3086676796124 5082.797153041637 2104.759168457683 1942.6333638772264 2560.9087250611283 2339.1945847454244 0.0 0.0 6.175378552465556 0.4376459263682215 1.6968698087643674 2.1728834301293496 0.8997794292887972 0.8304710418473562 1.094782256149859 1.0 11.191796161218134 -7.276688724811754 22.355352864024177 0.9421304129000279 1.807192097485719 0.050720194476057356 1.6635928249046659 711.0570670579738 1042389.1734796326 0.7084997319661548 0.4805242759589742 5.2882414412802105e-08 7.276688724811754 0.8650616845856911 RPT(ph)LGVQLDDK ddPTM_PC-9_AZD4547_30min_R2 1 RPTLGVQLDDK 11 1 H7C072;Q13769 H7C072 THOC5 THO complex subunit 5 homolog 1 RPT(1)LGVQLDDK 82.505 0.011775 2604700.0 17978.0 22743.0 19675.0 26270.0 17221.0 29442.0 24408.0 17505.0 17140.0 20269.0 True False 23694.630034369795 30094.229986394937 19414.096644583366 20213.857367454097 14830.161406097666 27600.98708572097 26580.264715438647 14800.004474882728 18045.98540799648 19559.388479403435 1.2114197772246755 1.5386079180381829 0.9925717598495952 1.0334606007104892 0.75821191555729 1.4111375268600834 1.3589517250719974 0.7566701019547484 0.9226252358042476 1.0 14.255573644955986 -5.274580025358663 24.433287489625307 1.0364042163128977 1.3750138511984615 0.2889446988198756 0.21675586260027563 677.4906124138329 1259705.2629951881 0.059829871278519964 0.12583857734630738 5.313980723136697e-06 5.274580025358663 0.33860963488556384 RPT(ph)LQAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPTLQAVR 8 1 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 RPT(1)LQAVR 80.706 0.024486 0.0 5808.6 4436.9 6673.9 4755.2 4979.4 3602.2 3099.2 4622.6 3006.7 2845.4 True False 6791.881254920551 4877.366109549433 6833.031086906695 4488.7815605664055 4003.722314921985 3413.2942906893204 2805.621339735075 4501.261648049555 3050.667299382447 3361.2484958259943 2.0206424081274337 1.4510578779302263 2.0328848329398936 1.3354506714218197 1.1911414225677799 1.015484066390199 0.8346961979214276 1.339163603535779 0.9075994539442032 1.0 11.71478148914778 -6.030191479232989 2.5174681134449983 1.047439763347795 1.7973164501938852 0.7420129926745074 0.20529807371850486 0.14228047363492619 1.8001829789889983 0.06065394398645552 0.09004987163793318 9.32842922257712e-07 6.030191479232989 0.7498766868460902 RPTETNPVTS(ph)NSDEECNETVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPTETNPVTSNSDEECNETVK 21 1 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 RPTETNPVT(0.019)S(0.499)NS(0.482)DEECNETVK 101.85 7.2102e-05 10826000.0 23287.0 29915.0 25817.0 27115.0 31006.0 24493.0 29771.0 19560.0 20282.0 19697.0 True False 27229.02916078484 32884.7634986525 26432.575191517724 25595.8344580161 24930.596878433356 23208.543962537755 26950.875356625238 19046.57072553311 20578.58588022576 23267.91017863378 1.1702395682182252 1.4133097148041076 1.136009851705116 1.1000487049120544 1.0714583599057543 0.9974485797976588 1.1582851725709948 0.8185767685755896 0.88441917311175 1.0 14.506054019587372 -6.062259989212654 0.5582652388222382 0.9230621920089139 1.3352057858701574 0.5771638288241481 0.10251337459645948 0.8771523703351747 0.5114547243296911 0.07485014108621524 0.19958165146870302 8.66443026704036e-07 6.062259989212654 0.41214359386124344 RPTETNPVTS(ph)NSDEECNETVKEK ddPTM_PC-9_Lapatinib_30min_R1 1 RPTETNPVTSNSDEECNETVKEK 23 2 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 RPT(0.002)ET(0.005)NPVT(0.097)S(0.469)NS(0.426)DEECNETVKEK 70.538 0.002773 8453800.0 7451.3 7716.3 6459.9 5108.8 9185.3 6243.8 6972.5 6295.7 7832.4 6302.8 True False 7345.043095598935 7698.4333814380625 5928.791957935115 5484.518194457206 8645.038712994612 5976.767229008691 7333.501933295479 6588.221205582808 6950.232633171553 7392.230582046906 0.9936166105853661 1.0414222467755285 0.8020301710195618 0.7419300755819422 1.1694763328933935 0.8085201297053867 0.9920553548621632 0.8912358905014744 0.9402077703110603 1.0 12.851794043362391 RPTETNPVTSNS(ph)DEECNETVK ddPTM_PC-9_AZD4547_30min_R2 2 RPTETNPVTSNSDEECNETVK 21 1 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 RPTETNPVTSNS(1)DEECNETVK;RPTETNPVTS(0.009)NS(0.99)DEECNETVK 130.27 1.4840000000000001e-06 35629000.0 67296.0 72312.0 74678.0 61782.0 66508.0 75809.0 70444.0 83414.0 74910.0 76781.0 True False 88694.72815624384 95685.43986176806 73687.72092626162 47539.11442238483 57274.51221164529 71068.65124588757 76713.37953188959 70524.28296303174 78869.58966820396 74092.92056031768 1.197074261420686 1.2914248640512462 0.9945311963546343 0.6416148002113659 0.7730092399991058 0.9591827492888728 1.0353671977262475 0.9518356467757162 1.0644686303598692 1.0 16.177048081858622 -5.367961338987739 4.733982268693777 0.9104793362234616 1.2421078680256772 0.5232617156656975 0.12202195293164389 0.17520742055376437 6.150159918886233 0.035738110377840644 0.07798086207747758 4.285866716007426e-06 5.367961338987739 0.33162853180221563 RPTETNPVTSNS(ph)DEECNETVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPTETNPVTSNSDEECNETVK 21 1 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 RPTETNPVT(0.001)S(0.005)NS(0.994)DEECNETVK 95.444 0.00015963 7791000.0 30944.0 39894.0 31236.0 32572.0 32850.0 21806.0 30781.0 23812.0 23470.0 25767.0 True False 36182.208028141285 43854.412669739046 31980.784703189674 30747.096439848778 26413.27831569813 20662.45497273092 27865.200844858467 23186.96023089951 23813.204349122294 30438.353128540228 1.1887045227231885 1.4407616760520259 1.0506739496757858 1.0101432331113558 0.867763055516035 0.678829596511809 0.9154634853989827 0.7617678963438558 0.78234207509716 1.0 14.893602683280463 -5.717102310760103 1.4849806015028697 0.8189708107802673 1.318765747153845 0.7325632730794562 0.11034059977843563 0.19229486450268163 0.847984915509013 0.03415400213469244 0.08331076522087864 1.918216795400243e-06 5.717102310760103 0.49979493637357764 RPTETNPVTSNS(ph)DEECNETVK ddPTM_PC-9_Lapatinib_30min_R1 3 RPTETNPVTSNSDEECNETVK 21 1 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 RPTETNPVT(0.001)S(0.039)NS(0.96)DEECNETVK;RPTETNPVT(0.001)S(0.017)NS(0.982)DEECNETVK;RPTETNPVTS(0.007)NS(0.993)DEECNETVK 124.17 4.9855e-07 55624600.0 43720.0 78628.0 78058.0 71753.0 83036.0 82807.0 81291.0 98047.0 77648.0 70308.5 True False 43096.54478273394 78445.94169689008 71640.37255259366 77029.95498099101 78151.98573505714 79265.53764254498 85499.85022008218 102602.621558171 68902.46457031107 82461.23054481247 0.5226279610187685 0.9513069496853999 0.8687764186790985 0.9341354048692021 0.9477421719117625 0.9612461167368727 1.0368490702260187 1.244252855314995 0.8355740523768553 1.0 16.331428369851977 -4.469936109745126 1.5764134872869016 0.9915886863096784 5.212774934120908e-41 0.6137574270916493 0.10682474198305823 1.7519235742486958 2.2131811621826243 0.030332423027586385 3.3993310332112805 3.3889400810115194e-05 4.469936109745126 -0.9915886863096784 RPTETNPVTSNS(ph)DEECNETVKEK ddPTM_PC-9_AZD4547_30min_R2 2 RPTETNPVTSNSDEECNETVKEK 23 2 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 RPTETNPVT(0.01)S(0.283)NS(0.707)DEECNETVKEK;RPTETNPVT(0.009)S(0.283)NS(0.708)DEECNETVKEK 96.881 2.3689e-05 7429400.0 9668.0 8433.8 11211.4 13804.099999999999 14300.3 10999.2 8060.0 11768.900000000001 8950.5 11514.599999999999 True False 12742.222893107524 11159.860918052042 11062.729510601379 10621.778016218994 12314.950186145885 10311.418285213715 8777.324385711056 9950.286927417732 9423.605157192094 11111.477358771475 1.146762260470137 1.0043543768050225 0.9956128382755859 0.9559285118674242 1.1083089843516065 0.9279970567616566 0.789933156708651 0.8954963058591762 0.8480965089446937 1.0 13.439763026742265 -6.958354914055186 6.961772382626199 0.8723777650550872 1.0319834898171385 0.5260525392738165 0.07148908993049818 0.15333061707648551 19.57854949206235 0.02465152858347644 0.02158912784195086 1.1006394775234733e-07 6.958354914055186 0.15960572476205126 RPTPNDDTLDEGVGLVHS(ph)NIATEHIPSPAKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPTPNDDTLDEGVGLVHSNIATEHIPSPAKK 31 2 Q01581 Q01581 HMGCS1 Hydroxymethylglutaryl-CoA synthase, cytoplasmic 1 RPTPNDDTLDEGVGLVHS(0.471)NIAT(0.177)EHIPS(0.351)PAKK 44.726000000000006 0.008650299999999998 5186500.0 14017.0 11138.0 12218.0 22346.0 18109.0 17744.0 17445.0 13421.0 15619.0 12096.0 True False 16389.801251630564 12243.707031522361 12509.323457023036 21094.026066709484 14560.6714465442 16813.473403473225 15792.483309137331 13068.712970724933 15847.398326755056 14288.909048116679 1.1470295735272238 0.856867867959179 0.8754568606251856 1.4762516855329653 1.019019114581273 1.1766799933329612 1.1052266660776897 0.9146053716709345 1.1090698578450109 1.0 13.80260815105987 -14.522401949578066 0.0043076530282703945 0.5476255575161155 1.5508581559211594 0.003419422758735635 0.17290918166523817 2171357.2234129277 708.6072180330054 88067.68970222288 77290.4611677048 3.003295396644855e-15 14.522401949578066 1.0032325984050439 RPTPNDDTLDEGVGLVHSNIAT(ph)EHIPSPAK ddPTM_PC-9_AZD4547_30min_R2 1 RPTPNDDTLDEGVGLVHSNIATEHIPSPAK 30 1 Q01581 Q01581 HMGCS1 Hydroxymethylglutaryl-CoA synthase, cytoplasmic 1 RPTPNDDTLDEGVGLVHS(0.001)NIAT(0.715)EHIPS(0.284)PAK 87.95200000000001 2.2211e-08 6580200.0 34099.0 24008.0 32520.0 40477.0 37531.0 33006.0 33766.0 38837.0 33299.0 28907.0 True False 44941.772696739135 31768.11649797166 32088.763551809476 31145.65301341604 32320.468482216533 30942.12960231326 36771.10858659052 32835.63403547675 35059.117158744164 27894.974728606005 1.6111064137531488 1.1388472944337815 1.1503420907889472 1.1165327560406964 1.158648423118026 1.1092366959767284 1.3181983115002478 1.1771164647015848 1.2568255572854636 1.0 14.767717623929476 -4.7593293874211255 24.999980993023186 1.165853650916748 1.6111069829816769 0.7365854132652878 0.08110424671140416 28.150312571124008 333454.4623075545 0.019602556472221134 0.12560533277817088 1.7404863137652173e-05 4.7593293874211255 0.4452533320649288 RPTPNDDTLDEGVGLVHSNIATEHIPS(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 4 RPTPNDDTLDEGVGLVHSNIATEHIPSPAK 30 1 Q01581 Q01581 HMGCS1 Hydroxymethylglutaryl-CoA synthase, cytoplasmic 1 RPTPNDDTLDEGVGLVHSNIAT(0.004)EHIPS(0.996)PAK;RPTPNDDTLDEGVGLVHS(0.004)NIAT(0.154)EHIPS(0.842)PAK;RPTPNDDTLDEGVGLVHS(0.01)NIAT(0.204)EHIPS(0.787)PAK;RPTPNDDTLDEGVGLVHS(0.09)NIAT(0.332)EHIPS(0.578)PAK 88.001 3.074e-09 33678400.0 90920.0 89536.0 119790.0 158563.0 137463.0 131822.0 116786.0 134811.0 112273.0 128612.0 True False 119830.66874651778 118476.76102809013 118201.50633060446 122008.75012392929 118378.63523409792 123579.14950118584 127179.72775553989 113979.05759859543 118207.52157012763 124109.33302644623 0.9655250400949563 0.9546160481165759 0.9523982076788465 0.9830747386091477 0.9538254081896712 0.9957280930262721 1.0247394346115726 0.9183761995909514 0.9524466749405462 1.0 16.921252084705117 -5.752509139126219 24.78352995270669 0.9740516995335841 0.9572233916740204 0.07760642200887646 0.028050814351829306 548.5123478338462 1522231.0040285997 0.008036617164518844 0.013671483283329726 1.7680350114933508e-06 5.752509139126219 -0.016828307859563685 RPTPNDDTLDEGVGLVHSNIATEHIPS(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RPTPNDDTLDEGVGLVHSNIATEHIPSPAK 30 1 Q01581 Q01581 HMGCS1 Hydroxymethylglutaryl-CoA synthase, cytoplasmic 1 RPTPNDDTLDEGVGLVHS(0.018)NIAT(0.062)EHIPS(0.919)PAK;RPTPNDDTLDEGVGLVHS(0.03)NIAT(0.262)EHIPS(0.708)PAK 60.172 0.00024059 12619100.0 37504.0 39557.0 37791.0 57147.0 58607.0 46538.0 53890.0 39479.0 43799.0 37353.0 True False 43852.68646223537 43483.957536894435 38692.0807631656 53945.238863073755 47123.3790638697 44097.46535453321 48785.14907018687 38442.71808145814 44439.477515432794 44124.803213814674 0.9938330206197019 0.9854765204546091 0.8768782622253557 1.2225604407043447 1.0679566962718199 0.999380442352366 1.1056173742869662 0.8712269581164369 1.0071314607363417 1.0 15.429302223868978 -10.319070523637436 10.16014073034282 1.0000002598190822 1.0152729476975213 0.0019013658338635775 0.09771104681851464 0.0 0.0 0.0961847363739073 0.023328225155400523 4.7965555264127994e-11 10.319070523637436 0.01527268787843905 RPTPNDDTLDEGVGLVHSNIATEHIPS(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 2 RPTPNDDTLDEGVGLVHSNIATEHIPSPAK 30 1 Q01581 Q01581 HMGCS1 Hydroxymethylglutaryl-CoA synthase, cytoplasmic 1 RPTPNDDTLDEGVGLVHS(0.06)NIAT(0.289)EHIPS(0.651)PAK;RPTPNDDTLDEGVGLVHS(0.017)NIAT(0.27)EHIPS(0.713)PAK 62.717 0.00011264 27827000.0 70294.0 59271.0 64372.0 52354.0 62047.0 60665.0 52456.0 53677.0 57700.0 51723.0 True False 69291.59466965926 59133.761641099394 59079.5826431058 56204.28780782422 58397.51744909547 58070.499367022065 55171.91501082077 56171.02937752253 51201.21839206354 60663.251633434666 1.142233441233293 0.9747872072275748 0.973894096546318 0.926496458637689 0.9626506307635769 0.9572599193646982 0.9094783666428568 0.9259482118918229 0.8440236389149292 1.0 15.888535210015714 -1.5228804517069967 0.9384290227554948 0.9295448730693807 137.44971193449362 0.7052794916559146 0.03970543964337185 621.107042279316 1.145945561655405 0.012792332112326667 181921.54769834585 0.02999988212445395 1.5228804517069967 136.52016706142425 RPTSNGVVSS(ph)PNSTSRPTLPVK ddPTM_PC-9_AZD4547_30min_R2 1 RPTSNGVVSSPNSTSRPTLPVK 22 2 Q7Z422-4;Q7Z422-5;Q7Z422;Q7Z422-2;Q7Z422-3 Q7Z422-4 SZRD1 SUZ domain-containing protein 1 1 RPT(0.002)S(0.002)NGVVS(0.231)S(0.656)PNS(0.026)T(0.026)S(0.026)RPT(0.033)LPVK 47.7 0.016689 11375000.0 22859.0 18822.0 26399.0 38564.0 28634.0 30556.0 28023.0 30676.0 26576.0 29285.0 True False 30127.686503262827 24905.84341572901 26048.932011199828 29673.66560786068 24658.663358817736 28645.328489616553 30516.992712255716 25935.729064353203 27980.753104020696 28259.74106366026 1.0660991703849896 0.8813188825624417 0.9217682480713401 1.0500331740837714 0.8725721620474003 1.0136444076075461 1.0798751709547012 0.9177624453786822 0.990127724135508 1.0 14.786460626258645 RPTT(ph)ADER ddPTM_PC-9_AZD4547_30min_R2 1 RPTTADER 8 1 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 RPT(0.005)T(0.995)ADER 72.2 0.028294 69955000.0 8008.1 7895.2 20854.0 36307.0 26168.0 13864.0 10371.0 23381.0 11412.0 17760.0 True False 10554.509221172362 10447.169000949087 20577.46233423845 27936.98208755826 22535.024892559293 12997.081888337605 11293.998908710848 19768.003691929902 12015.215021940248 17138.227805723287 0.6158460104986876 0.609582806307445 1.2006762057023561 1.6300974875727083 1.3148981999780487 0.7583679033603024 0.6589945609743403 1.1534450303740509 0.7010768650144669 1.0 14.064930313499234 -8.262394736901644 24.564335665081543 0.8505384970124373 0.9999447186707794 0.02873976415541879 0.3285333842529352 339.5080970431018 8728618.762156716 0.29382494856115693 0.09267189757714377 5.465189975969052e-09 8.262394736901644 0.14940622165834205 RPVS(ph)FPETPYTVSPAGADR ddPTM_PC-9_AZD4547_30min_R2 2 RPVSFPETPYTVSPAGADR 19 1 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 RPVS(0.996)FPET(0.004)PYTVSPAGADR;RPVS(1)FPETPYTVSPAGADR 77.543 0.0015494999999999999 9777600.0 11463.8 12816.9 15645.5 24328.9 20843.9 23493.1 13824.0 21346.4 19194.2 17850.4 True False 15109.049938147098 16959.71227685991 15438.030447411902 18720.247982758057 17950.084276903715 22024.072743140805 15054.309219363478 18047.804371473114 20208.76622626406 17225.462929238893 0.8771346233314086 0.9845722200053103 0.8962331236513266 1.0867776418932626 1.042066872202014 1.2785765371656075 0.8739567279675226 1.0477398747199043 1.1731914729537538 1.0 14.072255135003997 -5.7651669542182775 24.99744087252162 1.0728861551704794 0.9258391988228563 0.3152071517879974 0.10282430255534579 116.54957740194989 781599.4373200214 0.02846533916576392 0.04412422882827481 1.717248104925564e-06 5.7651669542182775 -0.1470469563476231 RPVS(ph)FPETPYTVSPAGADR ddPTM_PC-9_Lapatinib_30min_R1 1 RPVSFPETPYTVSPAGADR 19 1 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 RPVS(0.986)FPET(0.014)PYTVSPAGADR 67.88 0.0040546 4912500.0 4315.7 7353.2 7578.0 5651.3 8242.7 6779.5 8236.6 10262.0 8812.3 7298.6 True False 4254.157326597547 7336.174117179263 6954.966091925933 6066.915454184153 7757.880591771711 6489.556588786388 8663.050846006683 10738.809983272844 7819.765976367101 8560.153285226814 0.49697209674263754 0.8570143398997416 0.8124814895463232 0.7087391138958327 0.906278232792902 0.7581121940872391 1.0120205278283334 1.2545114118231941 0.9135077043377857 1.0 13.063420915617547 -7.323108770529093 4.210029699997487 1.0741832735590024 0.7674375745855898 0.5370846298122196 0.1307390219918789 0.17084715380093338 6.149069719455725 0.054819878821208375 0.036568589856326626 4.7521619152678524e-08 7.323108770529093 -0.30674569897341264 RPVSAIFT(ph)ESIQPQKPGPGAAATVGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RPVSAIFTESIQPQKPGPGAAATVGK 26 2 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 RPVS(0.257)AIFT(0.371)ES(0.371)IQPQKPGPGAAATVGK 41.49100000000001 0.037001 6312800.0 17132.0 11065.0 17106.0 13385.0 15340.0 13433.0 14581.0 10774.0 13301.0 9903.6 True False 20032.10922757615 12163.46007396256 17513.87191486625 12635.081844755501 12334.237119111383 12728.549832555002 13199.782122701701 10491.19391599661 13495.501961980215 11699.044283145535 1.712285956249932 1.0396968999840521 1.4970344150331976 1.0800097460062177 1.054294421030695 1.0879991155254147 1.1282786698840208 0.896756492418014 1.1535559346008104 1.0 13.514103057709958 -1.5228787452803376 0.5345093494323938 1.0440552012579976 23.26675634791006 0.5588365490454885 0.15598650491979094 94.88187968364895 0.9119656884257379 0.0757535533906722 2405.551249428832 0.029999999999999995 1.5228787452803376 22.222701146652064 RPYDLDR ddPTM_PC-9_AZD4547_30min_R2 1 RPYDLDR 7 1 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3;K7EII0 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 0 61.961999999999996 0.04359 1934500.0 1273.8 869.03 3473.1 3245.0 2828.1 1647.2 1159.5 2937.9 709.18 3089.8 False True 1678.8419033140651 1149.926952692115 3427.0444247167716 2496.91538475023 2435.467131559421 1544.20032360572 1262.6932537508656 2483.915061225821 746.665806980335 2981.6270424619256 0.5630623412671517 0.38567095626508063 1.1493873566048238 0.8374338403801603 0.816824873424967 0.5179052583084556 0.42349134743165645 0.8330736962912891 0.2504222682270194 1.0 11.541884093711621 -6.760305905697985 24.998639799403136 0.5832026667631889 0.7572016872173122 0.06565558810741079 0.2676185229076936 81.50665992300898 1797631.8288770304 0.09098924308549564 0.08616326694849308 1.7365771981994358e-07 6.760305905697985 0.1739990204541233 RPYDLDR ddPTM_PC-9_Lapatinib_30min_R1 1 RPYDLDR 7 1 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3;K7EII0 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 0 76.47800000000001 0.019740999999999998 1896700.0 2960.1 1461.3 3020.2 2848.0 3624.7 2572.7 1268.7 4034.4 2567.1 1160.1 False True 2917.888431184141 1457.9164496320036 2771.890814309143 3057.4514206494923 3411.502272434389 2462.6716182566174 1334.3870782032243 4221.852952301302 2277.9661652385835 1360.621739263916 2.144525805359168 1.0715075377383896 2.037223670855583 2.247098758177674 2.5073113077555123 1.8099605108388908 0.9807186227416267 3.102885122639071 1.6742097377269178 1.0 10.410050329654593 RQAS(ph)ESSSRPH ddPTM_PC-9_AZD4547_30min_R2 2 RQASESSSRPH 11 2 A0A2R8Y653;Q9BZX2-2;Q9BZX2 A0A2R8Y653 UCK2 Uridine-cytidine kinase 2 1 RQAS(0.997)ES(0.002)SSRPH;RQAS(0.965)ES(0.024)S(0.005)S(0.005)RPH 106.54 0.0068065 12212900.0 8499.0 3407.5 12070.6 14075.2 12949.1 12413.5 8447.8 12112.3 17785.7 20997.5 True False 11201.505209818044 4508.907737705699 11910.535957210066 10830.380099672244 11151.340982736154 11637.281882636966 9199.637834442909 10240.622347964696 18725.81579177381 20262.383916141585 0.5528226716153872 0.22252602439902328 0.5878151359930456 0.534506706836428 0.5503469398708156 0.5743293548675868 0.4540254430335918 0.5054006670857089 0.9241664687271224 1.0 14.306516300068992 -8.294021067423344 4.063790384956259 0.9904859335811227 0.49376566585449916 0.7773081507642965 0.09974137723930927 0.09795084844910663 3.5054469965544564 0.09217122657261363 0.025803995268070257 5.081347925802109e-09 8.294021067423344 -0.49672026772662353 RQAS(ph)ESSSRPH ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RQASESSSRPH 11 2 A0A2R8Y653;Q9BZX2-2;Q9BZX2 A0A2R8Y653 UCK2 Uridine-cytidine kinase 2 1 RQAS(0.971)ES(0.018)S(0.005)S(0.005)RPH;RQAS(0.999)ES(0.001)SSRPH;RQAS(0.992)ES(0.005)S(0.003)SRPH 111.72 0.004997 11306900.0 1104.1999999999998 3239.83 6664.53 6629.83 23292.8 32967.799999999996 13454.9 29682.0 33528.6 26906.8 True False 1291.1192510558944 3561.4589111094556 6823.437670570774 6258.382119298865 18728.743048763863 31238.910531505007 12180.354466959687 28902.878950678616 34018.89234512064 31784.789845888405 0.04062066344676211 0.11204915710871552 0.21467619272157734 0.19689864710898608 0.5892360194788755 0.98282576927423 0.3832133081897757 0.909330503389105 1.0702884149954899 1.0 14.956048929226656 -6.438598209483085 0.6215416426744611 0.9723699804487586 3.9827853959654894e-22 0.7869627439540422 0.1792019394892523 0.42499843247140123 0.35785808501999994 0.13592096266949175 0.21307702011058335 3.642518704056743e-07 6.438598209483085 -0.9723699804487586 down RQAS(ph)ESSSRPH ddPTM_PC-9_Lapatinib_30min_R1 3 RQASESSSRPH 11 2 A0A2R8Y653;Q9BZX2-2;Q9BZX2 A0A2R8Y653 UCK2 Uridine-cytidine kinase 2 1 RQAS(0.689)ES(0.058)S(0.249)S(0.004)RPH;RQAS(0.989)ES(0.008)S(0.003)SRPH;RQAS(0.999)ESSSRPH 101.38 0.010564 14188280.0 9410.5 9719.130000000001 14389.6 17019.5 28402.74 20270.489999999998 32868.95 33013.69 47350.0 31383.4 True False 9276.30454432565 9696.625951626567 13206.54263346231 18271.170805387654 26732.146675135355 19403.568395520102 34570.743401992484 34547.626559800716 42016.944382395304 36807.97887424809 0.25201885102188043 0.2634381524928173 0.3587956480463529 0.49639158041819803 0.7262595636251554 0.5271565836801594 0.9392187362446885 0.9385906973547852 1.1415172923768317 1.0 15.167730913076015 -6.654728496996193 0.5505640495428206 1.0951079960389853 0.19285376766484805 0.9057969414361411 0.09539824410238026 0.26691442599018417 0.17466185635848794 0.08018726807589621 0.1084608432563198 2.2144786777253998e-07 6.654728496996193 -0.9022542283741373 down RQAVDVSPLR ddPTM_PC-9_Lapatinib_30min_R1 1 RQAVDVSPLR 10 1 M0R0F0;M0R0R2;P46782;M0QZN2 M0R0F0 RPS5 40S ribosomal protein S5;40S ribosomal protein S5, N-terminally processed 0 68.132 0.026441000000000003 2281000.0 33515.0 43816.0 28021.0 36997.0 31368.0 32163.0 27817.0 26516.0 24218.0 30953.0 False True 33037.06995410173 43714.54674404703 25717.221544187978 39717.882798374005 29522.99591186079 30787.463465614957 29257.22815037367 27748.030161417122 21490.313813154142 36303.18480772005 0.9100322775834322 1.2041518388973664 0.7084012513061687 1.0940605626955298 0.8132343227799282 0.8480650837848214 0.8059135391380863 0.7643414843183778 0.5919677275417479 1.0 15.14780849814942 -6.447900472026768 0.9021358544066665 0.7664369891300227 1.0007502135179445 0.21125031143177153 0.15448932168086943 0.8109580902821814 1.439228079090208 0.07908278170429307 0.10329102902844325 3.565328312736728e-07 6.447900472026768 0.2343132243879218 RQDLYSAR ddPTM_PC-9_AZD4547_30min_R2 1 RQDLYSAR 8 1 O43290 O43290 SART1 U4/U6.U5 tri-snRNP-associated protein 1 0 131.62 3.9722e-05 0.0 4704.7 5275.2 5489.7 10030.0 8977.2 5469.6 4486.3 5918.8 7502.2 6189.5 False True 6200.69673616084 6980.305237841552 5416.90299109374 7717.738461955259 7730.870737751582 5127.5850473493465 4885.572008885298 5004.18546049334 7898.75097595515 5972.807488937175 1.038154460468676 1.1686807670882517 0.9069274375788805 1.292145858752361 1.2943445359775432 0.8584882497630557 0.8179691071467391 0.837828018023699 1.3224519609220966 1.0 12.544193507323715 -6.774467270949287 24.998586419265344 0.9478755764268482 1.1371396471930078 0.19889314519050683 0.17103556805489686 370.5573869723121 711040.1279229197 0.06152909270527543 0.05458713976967756 1.680864593285525e-07 6.774467270949287 0.1892640707661596 RQDLYSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RQDLYSAR 8 1 O43290 O43290 SART1 U4/U6.U5 tri-snRNP-associated protein 1 0 95.50200000000001 0.017556 0.0 3642.3 3967.5 3439.2 3854.0 6769.4 4037.5 4402.3 4644.9 3707.8 3962.8 False True 4258.869451295855 4361.367179705959 3521.203571238631 3638.072874836586 5442.9846645444995 3825.7663923874647 3985.2822741080663 4522.97629667836 3762.0195605315557 4681.224270492461 0.909776845801029 0.9316723420403753 0.7521971535168946 0.7771626960427306 1.1627267462603115 0.8172576598183358 0.8513333358601974 0.9661951735977278 0.8036401042020135 1.0 12.192670168741365 -11.068018036055308 3.0360225120261513 1.0046479612651755 0.8874832731333764 0.08377264414605579 0.11320128394688789 53681298.13581053 60576456.35843049 2049831.6445338777 0.028620250450963804 8.550312030844487e-12 11.068018036055308 -0.11716468813179914 RQDLYSAR ddPTM_PC-9_Lapatinib_30min_R1 2 RQDLYSAR 8 1 O43290 O43290 SART1 U4/U6.U5 tri-snRNP-associated protein 1 0 ; 114.89 0.0023144000000000003 2531530.0 14041.4 10537.5 10958.5 10769.0 12184.2 13147.6 12499.400000000001 11384.900000000001 12108.6 10502.2 False True 13841.16706112261 10513.101066172065 10057.534431033295 11560.988184330894 11467.549311058863 12585.307796552523 13146.557771966085 11913.88401662083 10744.80195878926 12317.491276698136 1.1237001715850141 0.8535099258450816 0.8165245832209226 0.9385830218692038 0.9309971530284606 1.0217427813698585 1.0673080643325765 0.9672329980991472 0.8723206469093229 1.0 13.588420829476892 -6.644766462899835 6.5436839623671235 0.9885671018481503 0.9210536758772023 0.07558505928919057 0.08847754712545912 0.5152682983059131 27.54444726529546 0.030283887433556957 0.03021353056375084 2.2658624227461128e-07 6.644766462899835 -0.067513425970948 RQDS(ph)MEALQMDR ddPTM_PC-9_AZD4547_30min_R2 1 RQDSMEALQMDR 12 1 Q8TDR0-2;Q8TDR0 Q8TDR0-2 TRAF3IP1 TRAF3-interacting protein 1 1 RQDS(1)MEALQMDR 88.22399999999999 0.0049576 12303000.0 44278.0 43800.0 62008.0 76224.0 69410.0 60283.0 49138.0 61125.0 49364.0 59502.0 True False 58357.482960386384 57957.49344431686 61185.733404692524 58651.73444906062 59773.619603811574 56513.494480283895 53511.186807080645 51679.53576276529 51973.28026139663 57418.85309099928 1.0163470675371995 1.0093808971151674 1.0656035450189745 1.021471716895972 1.041010336954665 0.9842323807951974 0.9319445430627875 0.9000447236530809 0.9051605433328261 1.0 15.809236893367745 -7.069337683077685 2.6110239756637936 0.925205997294609 1.0309518010406744 0.6966351751661735 0.029716949156097017 0.1462739374854765 1.9639078017484493 0.012219039555174008 0.009339551543028459 8.524370489393118e-08 7.069337683077685 0.10574580374606546 RQDS(ph)MEALQMDR ddPTM_PC-9_Lapatinib_30min_R1 4 RQDSMEALQMDR 12 1 Q8TDR0-2;Q8TDR0 Q8TDR0-2 TRAF3IP1 TRAF3-interacting protein 1 1 RQDS(1)MEALQMDR;RQDS(1)MEALQMDR;RQDS(1)MEALQMDR;RQDS(1)MEALQMDR 84.17299999999999 0.010838 15261900.0 107729.0 98858.0 109379.0 95215.0 112302.0 110619.0 97263.0 97568.0 117451.0 89561.0 True False 106192.76470492092 98629.1003748175 100386.28083515003 102217.42872792862 105696.61715422697 105888.08323548353 102298.80222848599 102101.36546949562 104222.43156613961 105041.49951746894 1.0109600985585752 0.9389536595335349 0.9556820998966725 0.9731147136844647 1.0062367506153993 1.0080595166853439 0.9738893932247528 0.9720097860228627 0.9922024347035039 1.0 16.68059989108656 -6.0407886741209245 8.700972297105547 0.9905061076590914 0.9653676794764051 0.22105480737523764 0.02033977209052561 0.5393716567959022 109.94214174445872 0.006089706473004364 0.007963093276100126 9.103561403663527e-07 6.0407886741209245 -0.0251384281826863 RQDSDLVQCGVTS(ph)PSSAEATGK ddPTM_PC-9_AZD4547_30min_R2 1 RQDSDLVQCGVTSPSSAEATGK 22 1 Q9HC52 Q9HC52 CBX8 Chromobox protein homolog 8 1 RQDSDLVQCGVT(0.241)S(0.321)PS(0.197)S(0.241)AEATGK 144.43 3.8288000000000003e-05 15901000.0 22513.0 22011.0 24471.0 33218.0 31910.0 28534.0 18587.0 32603.0 26110.0 28480.0 True False 29671.66570050991 29125.625301435124 24146.49855093264 25560.103312984036 27479.847306693922 26749.764469260306 20241.206992209856 27564.955492407982 27490.12129537854 27482.92386863734 1.0796400645846236 1.0597717128151851 0.8786000596715212 0.9300358082406375 0.9998880555082813 0.9733230931730051 0.7365012212295393 1.0029848215627544 1.0002618872277056 1.0 14.746247878115526 -5.179911384898195 6.779567259752535 0.936113815274596 1.0725995689347312 0.3032501844288763 0.07839606117070673 0.3061151831578529 21.41751575010255 0.0204224771852168 0.05516450565320598 6.608282721721261e-06 5.179911384898195 0.13648575366013516 RQDSDLVQCGVTS(ph)PSSAEATGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RQDSDLVQCGVTSPSSAEATGK 22 1 Q9HC52 Q9HC52 CBX8 Chromobox protein homolog 8 1 RQDSDLVQCGVT(0.046)S(0.572)PS(0.285)S(0.097)AEATGK;RQDSDLVQCGVT(0.279)S(0.695)PS(0.019)S(0.007)AEATGK 119.29 4.8718e-07 16892200.0 37296.0 39995.0 37077.0 39943.0 49538.0 41644.0 43665.0 39983.0 31125.0 37684.0 True False 43609.47617042263 43965.439282253275 37961.05629530551 37705.1232069532 39831.38451150847 39460.11532992784 39528.73509277623 38933.48861549029 31580.144242285114 44515.81089362016 0.9796401614391929 0.9876364913876979 0.8527544603426723 0.8470051977050912 0.8947693799556722 0.8864292155482921 0.8879706850053436 0.8745991106065664 0.709414107220297 1.0 15.442030215550211 -5.258625743463762 24.47941909861233 0.8660571430417529 0.9836383440936347 0.31800160733970084 0.06696433540011948 197.02713441444612 1714157.1813352457 0.01653647130148014 0.039867107305822026 5.512825636613965e-06 5.258625743463762 0.11758120105188186 RQDSDLVQCGVTS(ph)PSSAEATGK ddPTM_PC-9_Lapatinib_30min_R1 2 RQDSDLVQCGVTSPSSAEATGK 22 1 Q9HC52 Q9HC52 CBX8 Chromobox protein homolog 8 1 RQDSDLVQCGVT(0.016)S(0.939)PS(0.034)S(0.011)AEATGK;RQDSDLVQCGVT(0.153)S(0.604)PS(0.12)S(0.12)AEAT(0.004)GK 119.29 4.8718e-07 33220000.0 60497.0 63413.0 74718.0 58454.0 73908.0 70775.0 68345.0 75063.0 73945.0 58756.0 True False 59634.30168620896 63266.17109458308 68574.97445982089 62752.90215682767 69560.87674871871 67748.11823458309 71883.56968534665 78550.70101095396 65616.5354246298 68911.89631255127 0.8653702027838038 0.9180732860352313 0.9951108317901708 0.9106250954437627 1.0094175384932667 0.9831120874588933 1.0431227920258832 1.1398714186399066 0.9521800869769235 1.0 16.0724654375099 -5.367258074658699 0.5165373527376094 1.0416709430921847 0.82651353991864 0.46529558545087246 0.05352519255630834 2.209263242308906 0.6942844977949221 0.036259034068056445 0.2685846013403809 4.292812553513527e-06 5.367258074658699 -0.2151574031735447 RQEAIAQNR ddPTM_PC-9_AZD4547_30min_R2 2 RQEAIAQNR 9 1 Q6P2Q9 Q6P2Q9 PRPF8 Pre-mRNA-processing-splicing factor 8 0 ; 120.99 0.0010402 1568660.0 3316.2799999999997 2823.88 4989.0 6437.799999999999 6142.79 5142.1 3598.54 5350.76 3976.41 2265.1 False True 4370.78805709088 3736.643986016834 4922.842600245308 4953.664673018502 5289.969640773628 4820.563674121519 3918.803088704302 4523.922990232708 4186.594914598093 2185.799538442783 1.9996289596642225 1.709509001305266 2.2521930825149963 2.266294134432663 2.4201531511633183 2.2054006277061466 1.7928465167012309 2.069687961163932 1.9153608741178183 1.0 11.093945380934624 -9.34979654443615 0.7391216607014068 0.9733586604612177 2.1177160510181547 0.7224768513885941 0.20259316194940025 2.0169537718836 1.3520858235210096 0.361963589337843 0.07955628403491335 4.468929007116844e-10 9.34979654443615 1.144357390556937 RQEAIAQNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RQEAIAQNR 9 1 Q6P2Q9 Q6P2Q9 PRPF8 Pre-mRNA-processing-splicing factor 8 0 96.665 0.003184 333780.0 560.88 528.86 884.76 925.38 867.17 975.28 568.43 832.82 922.19 0.0 False True 655.8259061150432 581.3617256860223 905.8560338709855 873.5339587224387 697.2542635319314 924.1345999176831 514.5841953231833 810.9593574457298 935.6752841379247 0.0 0.0 RQEAIAQNR ddPTM_PC-9_Lapatinib_30min_R1 2 RQEAIAQNR 9 1 Q6P2Q9 Q6P2Q9 PRPF8 Pre-mRNA-processing-splicing factor 8 0 ; 145.9 0.00029565 1884290.0 3772.46 1957.4299999999998 2125.15 1857.6200000000001 2558.1000000000004 1366.99 2191.6 2190.9700000000003 2168.11 1799.17 False True 3718.664028615562 1952.89769109914 1950.4283703162293 1994.2355716386614 2407.6375874181062 1308.5270243093291 2305.070324418841 2292.7704647292253 1923.9146205895481 2110.1541372566694 1.7622712781778371 0.9254763226150046 0.924306113889816 0.9450663041285177 1.140977118642235 0.6201096882953275 1.0923705921386269 1.0865417005555662 0.9117412735975562 1.0 11.043132669819164 -4.759901988174634 24.999098655306874 0.9609105464672627 1.7622722624195828 0.7542194557768895 0.13726845734660353 18.696972572487205 303926.3134047962 0.03327761958976734 0.20467303926855948 1.7381930608854434e-05 4.759901988174634 0.8013617159523201 RQEELDR ddPTM_PC-9_AZD4547_30min_R2 1 RQEELDR 7 1 Q9UQE7 Q9UQE7 SMC3 Structural maintenance of chromosomes protein 3 0 107.66 0.0045747 0.0 3305.7 3949.8 2887.4 5734.9 3262.4 4950.5 3995.5 3645.7 3114.0 3517.1 False True 4356.843837168554 5226.495607451202 2849.1111894063533 4412.807408321753 2809.4720731231064 4640.944452410217 4351.091759690886 3082.340834851755 3278.599682643003 3393.9673995219246 1.2837023236529204 1.5399368916116896 0.8394633342110711 1.3001914540909683 0.8277840481080784 1.3674098499189893 1.282007529095236 0.9081822162717104 0.9660080067666023 1.0 11.72875699191923 -5.2496359084565745 24.995543445690203 1.0770969396085976 1.4118196149392421 0.341958469397872 0.19347164364146865 860.8253058880473 1822913.0774763338 0.04839862521127606 0.12585879685852175 5.6281296270170046e-06 5.2496359084565745 0.3347226753306445 RQEELDR ddPTM_PC-9_Lapatinib_30min_R1 2 RQEELDR 7 1 Q9UQE7 Q9UQE7 SMC3 Structural maintenance of chromosomes protein 3 0 ; 139.97 1.448e-05 2292000.0 11399.0 10599.7 11704.1 9124.0 9472.5 9745.7 12638.6 9455.400000000001 12529.9 9228.6 False True 11236.448169679421 10575.157045893624 10741.834077132522 9795.009396771757 8915.346173651538 9328.8991293363 13292.964866855265 9894.73240263477 11118.650716303588 10823.751213663456 1.0381288287091257 0.977032531248869 0.992431724000869 0.9049551494131667 0.8236835823052893 0.8618914963196755 1.2281291951790962 0.9141684991931512 1.0272455913683476 1.0 13.401912963690238 RQELEAELAK ddPTM_PC-9_Lapatinib_30min_R1 1 RQELEAELAK 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 104.07 0.0088498 0.0 32759.0 30132.0 29622.0 26200.0 29689.0 29197.0 30908.0 28375.0 32244.0 21119.0 False True 32291.850652735153 30062.231205304546 27186.59350422669 28126.83540063788 27942.75139081981 27948.312371531258 32508.26500599452 29693.406088030304 28612.341175627316 24769.39101070137 1.3036998220418008 1.2136847124063914 1.0975882892107034 1.135548120197463 1.128116205148016 1.128340715339205 1.312436990959917 1.1987943536924894 1.1551491582197415 1.0 14.5962707779423 -4.900516866483386 3.501884888248948 1.1559257485603998 1.3054295754223635 0.2954448696127936 0.07501573361620106 0.35012901486792325 7.526108189208218 0.01938663894593646 0.11539806961615723 1.2574280192994839e-05 4.900516866483386 0.14950382686196373 RQEMESGITT(ph)PPK ddPTM_PC-9_AZD4547_30min_R2 2 RQEMESGITTPPK 13 1 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 RQEMESGIT(0.158)T(0.842)PPK;RQEMES(0.001)GIT(0.08)T(0.919)PPK 79.804 0.011432 34483000.0 155579.0 157455.0 172208.0 253399.0 226921.0 193046.0 185969.0 218095.0 178137.0 190183.0 True False 205049.88575576933 208349.24954965533 169924.40940129166 194981.77552552344 195416.9360915791 180974.80310271337 202519.88073031008 184393.4290745247 187552.95814610666 183524.7510571999 1.1172873662793341 1.1352651255454818 0.9258936923899198 1.0624276802029426 1.0647988076042816 0.9861056999680017 1.103501732402241 1.0047333017062863 1.021949121661804 1.0 17.485615119627788 -5.208395820692813 24.999921926245776 1.0260641082473958 1.1262764135624312 0.4454653354876732 0.0466507706285952 297.81936113221764 140363.7504862472 0.011404243825016336 0.03017278070852448 6.18876766971732e-06 5.208395820692813 0.10021230531503544 RQEMESGITT(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 1 RQEMESGITTPPK 13 1 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 RQEMESGIT(0.162)T(0.838)PPK 72.66199999999999 0.019588 12279000.0 49491.0 48540.0 47738.0 45911.0 41170.0 38608.0 36560.0 39879.0 51423.0 32198.0 True False 48785.24926446216 48427.60861228874 43813.16591400898 49287.44809460628 38748.46154333428 36956.82583964373 38452.89791054612 41731.92392544704 45631.200231803894 37763.3813988618 1.2918665505396867 1.2823959830500868 1.160202404844221 1.305165116810536 1.026085591596471 0.978641860730131 1.0182588657620872 1.1050897027644049 1.2083451889501409 1.0 15.204700331456717 -6.265181783144377 24.954477539704392 1.055562697657618 1.254392042553599 0.6626739676900237 0.07120258396577014 210.72807834044488 1405140.026489887 0.02318428812055109 0.0272897812128057 5.43022990154462e-07 6.265181783144377 0.19882934489598103 RQEQPSIES(ph)TSPISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RQEQPSIESTSPISR 15 1 Q5T5P2;Q5T5P2-3 Q5T5P2 KIAA1217 Sickle tail protein homolog 1 RQEQPSIES(0.601)T(0.199)S(0.199)PIS(0.001)R 107.63 0.00037547 5714500.0 10827.0 12542.0 19387.0 12962.0 17229.0 18449.0 17079.0 18455.0 17106.0 14690.0 True False 12659.797257002518 13787.086872809614 19849.25960560693 12235.781163370999 13853.101129411356 17481.50196239167 15461.15347874786 17970.575804688826 17356.142888627426 17353.180714023983 0.729537568105396 0.794499123821581 1.1438398488852097 0.7051030796609319 0.7983032827068968 1.0073946817290955 0.8909694270775915 1.0355782090234267 1.0001706992310089 1.0 14.08291250228244 -6.766258597400316 24.997330358024616 0.9830554344123715 0.8420717044859699 0.2936351039760323 0.11793138613965351 181.30527332660517 940425.450585399 0.042102353905169775 0.03831574280557894 1.7129370482347094e-07 6.766258597400316 -0.14098372992640162 RQEQPSIEST(ph)SPISR ddPTM_PC-9_AZD4547_30min_R2 1 RQEQPSIESTSPISR 15 1 Q5T5P2;Q5T5P2-3 Q5T5P2 KIAA1217 Sickle tail protein homolog 1 RQEQPSIES(0.125)T(0.836)S(0.039)PISR 109.99 0.0019539 9034300.0 19791.0 21223.0 25866.0 36222.0 33063.0 26638.0 21129.0 25745.0 23172.0 26069.0 True False 26084.126321627147 28082.919711614966 25522.99993945582 27871.577524321357 28472.77315892264 24972.321648985646 23009.440067703345 21766.701811245694 24396.824613424422 25156.332244786063 1.0368811346508344 1.1163360158528464 1.0145755625701658 1.1079348632032024 1.1318332450798325 0.9926853170005117 0.9146579812910649 0.8652573673873738 0.9698084910005489 1.0 14.618633974342865 -6.979552510975846 4.405404934599815 0.9284340097029626 1.0808472337812292 0.6761059030378924 0.047031048280725574 0.11184049790723577 5.24156990039537 0.017347328161201367 0.014607717457036453 1.0482080460457873e-07 6.979552510975846 0.15241322407826652 RQEQPSIEST(ph)SPISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RQEQPSIESTSPISR 15 1 Q5T5P2;Q5T5P2-3 Q5T5P2 KIAA1217 Sickle tail protein homolog 1 RQEQPSIES(0.026)T(0.926)S(0.049)PISR 132.87 4.6388e-06 22645000.0 24850.0 24925.0 27558.0 35738.0 33960.0 28810.0 39207.0 31411.0 28260.0 25553.0 True False 29056.614190127668 27399.38927641363 28215.087234297 33735.715724159265 27305.78178389978 27299.152882893603 35493.02912590122 30586.49453270553 28673.249037332596 30185.556622563283 0.9625999133773884 0.9076986592963129 0.9347214493042217 1.1176111855741726 0.9045975903419018 0.9043779852808103 1.1758282137944966 1.0132824421678066 0.9498996290132925 1.0 14.881570784284902 RQEQPSIESTS(ph)PISR ddPTM_PC-9_AZD4547_30min_R2 4 RQEQPSIESTSPISR 15 1 Q5T5P2;Q5T5P2-3 Q5T5P2 KIAA1217 Sickle tail protein homolog 1 RQEQPS(0.005)IES(0.182)T(0.226)S(0.566)PIS(0.021)R;RQEQPS(0.148)IES(0.049)T(0.077)S(0.715)PIS(0.012)R;RQEQPSIES(0.008)T(0.18)S(0.631)PIS(0.18)R;RQEQPS(0.002)IES(0.017)T(0.147)S(0.805)PIS(0.029)R 146.67 5.4248e-05 61562000.0 70912.0 67079.5 97415.0 149387.0 120080.0 93973.0 87454.0 99291.0 89499.0 105131.0 True False 93460.54093877148 88761.63656388254 96123.21345016982 114948.13515614253 103408.96473167698 88096.85345446818 95237.236579153 83947.85743019608 94229.73442417027 101450.39568938599 0.9212437300384977 0.874926469835041 0.9474897835240921 1.1330476768970228 1.019305681648474 0.8683736801204522 0.9387566793799798 0.8274768852279492 0.928825696379505 1.0 16.630414966520064 -6.763231802153314 24.99935009639194 0.9035332740787722 0.980194664311493 0.15335209057565402 0.07663350285838119 90.41603910642225 1261036.1874277613 0.02854783881381478 0.026480494248267244 1.724916981842074e-07 6.763231802153314 0.0766613902327209 RQEQPSIESTS(ph)PISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RQEQPSIESTSPISR 15 1 Q5T5P2;Q5T5P2-3 Q5T5P2 KIAA1217 Sickle tail protein homolog 1 RQEQPSIES(0.006)T(0.039)S(0.956)PISR;RQEQPSIES(0.112)T(0.112)S(0.774)PISR 157.62 1.5078e-14 7461100.0 28274.0 30781.0 36504.0 33137.0 34763.0 33030.0 30678.0 32163.0 31702.0 24879.0 True False 33060.22976304507 33836.734255457886 37374.39380219094 31280.441321603503 27951.43969828354 31297.848654008158 27771.957750513895 31318.755329515407 32165.581775708346 29389.36575794436 1.1249044989719938 1.1513257732113984 1.2716978688826626 1.0643455724507411 0.9510732531112166 1.0649378728272796 0.9449662159860235 1.0656492415474976 1.0944632844624602 1.0 14.843006604556331 -5.944053156590122 7.67276127348842 1.0206437721717159 1.178667148673831 0.6172867784916714 0.057220221159464 0.1561701731540943 18.332249834370312 0.016135769416658813 0.02398345074633991 1.1374880515269395e-06 5.944053156590122 0.15802337650211506 RQEQPSIESTS(ph)PISR ddPTM_PC-9_Lapatinib_30min_R1 2 RQEQPSIESTSPISR 15 1 Q5T5P2;Q5T5P2-3 Q5T5P2 KIAA1217 Sickle tail protein homolog 1 RQEQPSIES(0.012)T(0.339)S(0.648)PIS(0.001)R;RQEQPSIES(0.001)T(0.112)S(0.887)PISR 170.47 5.896e-05 34378000.0 72090.0 55150.0 56656.0 49166.0 55597.0 55974.0 52494.0 50020.0 62074.0 42646.0 True False 71061.9833803131 55022.30356340591 51997.962378484495 52781.831652968016 52326.89376790758 53580.12250176699 55211.88246488534 52344.11180698766 55082.57245180163 50017.304277776915 1.420747967256734 1.1000653545387642 1.0395994572140026 1.055271418864119 1.0461758090220956 1.0712317122131083 1.103855620811944 1.0465200506666363 1.1012703152871686 1.0 15.610139683971887 -4.761194126787743 4.047203192502348 1.061525170715591 1.4597283903391658 0.9340849927125812 0.028716490517556557 0.05303939263641932 1.646562777735551 0.0068711411110417295 0.06383635044460027 1.7330291719116452e-05 4.761194126787743 0.39820321962357474 RQEQTLR ddPTM_PC-9_AZD4547_30min_R2 2 RQEQTLR 7 1 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 0 ; 153.04 0.00033613 2625100.0 7211.400000000001 2102.84 5616.1 5038.5 5059.3 5395.5 3905.3 4175.8 8625.3 11796.5 False True 9504.47519356182 2782.541906722538 5541.626844505447 3876.951669049012 4356.903524874859 5058.118532063293 4252.864134431439 3530.526060337922 9081.215749101057 11383.50812557515 0.834933755808393 0.24443623846246873 0.4868118670777034 0.3405761761911273 0.3827382101205051 0.44433741130287396 0.3735987261147199 0.3101439399341179 0.7977519450878618 1.0 13.474657609902758 -8.438771415666219 3.8690487650453105 0.9952950100139931 0.41858845760950275 0.615618112459078 0.15261897100799543 0.12385069840656242 3.3406354291083873 0.13653158506540092 0.03593086807838426 3.641066277201255e-09 8.438771415666219 -0.5767065524044903 RQEQTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RQEQTLR 7 1 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 0 ; 153.04 0.00033613 2048010.0 2019.17 5928.9 6479.3 4927.299999999999 9889.2 8850.5 3059.8 6588.2 8907.6 9828.2 False True 2360.9756005746513 6517.482009264946 6633.791084882082 4651.2393555221315 7951.482250216191 8386.364199585207 2769.953592966375 6415.266730774906 9037.856798476427 11609.974860011604 0.20335751188459433 0.56136917502838 0.5713872049569151 0.40062441233550466 0.6848836751235001 0.7223412884786233 0.23858394409680972 0.5525650837428682 0.7784561902546095 1.0 13.50307722777568 -14.52287874525393 0.14236743319221049 2.689470429824665 0.3584865247915511 0.48067725177883114 0.16716273730697884 132.00090361362203 1.139005152262048 62.817114154295155 1.0108096280451682 3.0000000001824164e-15 14.52287874525393 -2.330983905033114 RQEQTLR ddPTM_PC-9_Lapatinib_30min_R1 1 RQEQTLR 7 1 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 0 153.04 0.00033613 1813100.0 2707.0 3673.7 2958.5 3377.2 4949.9 2557.3 5222.4 5735.1 5155.5 4496.0 False True 2668.397683596998 3665.1937733614536 2715.2635501402556 3625.570554008938 4658.756613877832 2447.9302403574625 5492.79031860055 6001.573683011893 4574.833300178227 5273.127609456574 0.5060370014204894 0.6950701831657689 0.5149246806147517 0.6875560051888397 0.8834902090218795 0.4642273848953441 1.0416570061285912 1.1381430770324918 0.8675749268752647 1.0 12.36444319495892 -7.276330885090737 24.93837313598401 1.0233557174858903 0.6379526138644958 0.681378568757192 0.12924934301537147 464.8354388998155 778443.3842841366 0.05313680822836786 0.03599186419385692 5.29260051729676e-08 7.276330885090737 -0.3854031036213945 RQEVS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RQEVSSPR 8 1 H7C3L4;E7EQA9;Q92844;E7EV32;E7EMT6;E7ENY2;E7EVA2;E7EW82 H7C3L4 TANK TRAF family member-associated NF-kappa-B activator 1 RQEVS(0.606)S(0.394)PR 62.303000000000004 0.028642 3337200.0 5533.0 7124.4 7615.1 5159.6 11022.0 9245.3 7127.6 7834.7 8748.1 7087.2 True False 6469.6276182686715 7831.663348480689 7796.6728644275745 4870.524339648897 8862.318222089034 8760.460192579523 6452.422128644721 7629.047426550828 8876.024412720782 8372.053257755664 0.7727647470798598 0.9354531209205613 0.93127368214063 0.5817598371268079 1.0585597044403892 1.0463932709056825 0.7707096371690368 0.9112516597387226 1.060196840541865 1.0 13.031365773806545 RQEVSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 RQEVSSPR 8 1 H7C3L4;E7EQA9;Q92844;E7EV32;E7EMT6;E7ENY2;E7EVA2;E7EW82 H7C3L4 TANK TRAF family member-associated NF-kappa-B activator 1 RQEVS(0.016)S(0.984)PR;RQEVS(0.157)S(0.843)PR 91.853 0.0038569000000000003 6087500.0 24618.8 18157.0 33281.0 49015.0 43681.5 37667.0 31420.7 38981.4 37666.9 49360.0 True False 32447.066297148904 24025.89517051281 32839.6721945809 37715.349024201074 37617.077722574475 35311.67653548846 34217.08143003864 32957.720333458645 39657.89543549955 47631.921424014734 0.6812042287420714 0.5044074320797732 0.6894467242302768 0.7918082642197594 0.7897451246551846 0.7413447847536393 0.7183645002569077 0.6919250651274851 0.832590713325814 1.0 15.539641126298546 -14.522878745235445 0.06738762526830765 1.9803762219694518 0.34579866579991325 0.6483336717342689 0.07152220520834823 232.21331444387704 1.1268951432168326 36.01888446935021 4.815898592189995 3.0000000003101046e-15 14.522878745235445 -1.6345775561695386 RQFS(ph)APNLK ddPTM_PC-9_AZD4547_30min_R2 1 RQFSAPNLK 9 1 O60333-3 O60333-3 KIF1B Kinesin-like protein KIF1B 1 RQFS(1)APNLK 80.87100000000001 0.008278299999999999 26889000.0 85365.0 83036.0 128540.0 166870.0 153170.0 120500.0 120110.0 141950.0 115660.0 119300.0 True False 112509.29429769621 109875.76314251803 126835.47561345609 128400.69961579997 131904.98940665327 112965.11595100102 130799.55731609843 120014.88918649562 121773.55147543002 115123.34331209376 0.9772934928817087 0.9544177573496124 1.1017355122289259 1.115331573264963 1.1457710105679029 0.9812529127542632 1.1361688564021915 1.0424896092631808 1.0577659401821564 1.0 16.812820869731716 -5.257340821167106 24.97010802543207 1.0772342938774242 0.9658556139840497 0.3984001496681232 0.05219932953736335 308.744180425308 1880979.8648780813 0.013048810832708596 0.03197257298685278 5.529160271446021e-06 5.257340821167106 -0.11137867989337447 RQFS(ph)APNLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RQFSAPNLK 9 1 O60333-3 O60333-3 KIF1B Kinesin-like protein KIF1B 1 RQFS(1)APNLK;RQFS(1)APNLK;RQFS(1)APNLK 72.29 0.014983000000000002 35382700.0 140299.0 128061.0 134476.0 159736.0 178860.0 154443.0 166916.0 164915.0 154148.0 120638.0 True False 164048.84966843974 140774.04975433525 137682.4178430699 150786.50979109964 143813.66695725344 146343.73719863695 151104.5081128095 160586.15599188567 156402.12288063482 142508.7144301174 1.1511496003908244 0.9878276589419885 0.9661333230999415 1.0580862398070503 1.0091570016076172 1.0269107947809055 1.0603176705162636 1.1268514815676973 1.0974916411678837 1.0 17.120690617438463 -7.45051296464421 4.274749379840314 1.0857606157100954 1.0285164585655067 0.08942168743011569 0.055755136854100225 0.39601000410951515 13.735427534631562 0.02463914499311338 0.01567766795252276 3.543945506673186e-08 7.45051296464421 -0.05724415714458875 RQFS(ph)APNLK ddPTM_PC-9_Lapatinib_30min_R1 2 RQFSAPNLK 9 1 O60333-3 O60333-3 KIF1B Kinesin-like protein KIF1B 1 RQFS(1)APNLK;RQFS(1)APNLK 89.189 0.004372600000000001 25230900.0 161801.0 112995.0 124280.0 126985.0 122377.0 118258.0 104129.0 107645.0 118801.0 109614.0 True False 159493.6880693303 112733.36701989226 114062.17813467326 136323.90050954226 115179.02546243895 113200.38101286223 109520.29011289003 112646.57967739287 105420.3803500093 128560.63384852567 1.2406106231340688 0.8768886994810432 0.8872247648457072 1.0603860328672892 0.8959120845510659 0.8805213355298062 0.8518960029547645 0.876213630139042 0.8200051383864444 1.0 16.97208942156705 -4.758734533760522 24.992597240583994 0.9031030139802856 1.2406110746430299 0.6877498747022257 0.0677335921588206 43.37174081247969 400674.19484545325 0.01733204203878576 0.11609365353219404 1.742871893300602e-05 4.758734533760522 0.3375080606627443 RQGS(ph)FSEDVISHK ddPTM_PC-9_AZD4547_30min_R2 2 RQGSFSEDVISHK 13 1 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;E9PNZ4 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 RQGS(0.652)FS(0.348)EDVISHK;RQGS(0.975)FS(0.025)EDVISHK 119.62 0.00010321 31926000.0 115729.0 104948.0 159002.0 198300.0 195207.0 140519.0 136158.0 168762.0 147175.0 158856.0 True False 152528.41468726142 138870.3886300037 156893.52958993864 152584.99870445952 168105.87756809138 131732.32471633801 148275.7982270033 142683.71066496172 154954.37003628266 153294.4997920032 0.9950025271240571 0.9059058793265853 1.0234778795248283 0.9953716468072478 1.0966204123186738 0.8593414955858057 0.9672610460792169 0.9307816709572838 1.010827983042651 1.0 17.225946408451406 -6.766681136379878 24.999998282416477 0.9501674860436727 0.9985494639814547 0.1499949017473451 0.05824534823681405 274.2770590168475 1308126.32706441 0.020287310907200814 0.01841898624825654 1.71127128750996e-07 6.766681136379878 0.048381977937781984 RQGS(ph)FSEDVISHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RQGSFSEDVISHK 13 1 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;E9PNZ4 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 RQGS(0.968)FS(0.032)EDVISHK;RQGS(0.986)FS(0.014)EDVISHK;RQGS(0.979)FS(0.021)EDVISHK;RQGS(0.954)FS(0.046)EDVISHK 114.28 0.00014085 32510700.0 121706.0 119376.0 156685.0 178217.0 188798.0 198344.0 168146.0 190472.0 170015.0 132443.0 True False 142308.42199692872 131226.86035150092 160420.96463117137 168232.07927731 151804.3871977828 187942.49147534365 152217.9936083812 185472.31182176626 172501.14773822008 156453.8674817889 0.9095871152785232 0.8387575357750463 1.0253563380262507 1.0752823307285264 0.9702821006674872 1.2012645932016988 0.9729257324118192 1.185476043558687 1.1025687668494297 1.0 17.255377796344725 -5.399229822136341 3.7042495236466095 1.0761433813446237 0.8745227603123339 0.5069560594635822 0.0767922846373921 0.17468542158910055 4.223743400205583 0.01980541717613061 0.0449830164738593 3.988138002201109e-06 5.399229822136341 -0.20162062103228984 RQGS(ph)FSEDVISHK ddPTM_PC-9_Lapatinib_30min_R1 1 RQGSFSEDVISHK 13 1 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;E9PNZ4 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 RQGS(0.619)FS(0.381)EDVISHK 95.87299999999999 0.0015614000000000001 13536000.0 38388.0 37194.0 47188.0 43105.0 49983.0 48947.0 40816.0 35162.0 44001.0 33168.0 True False 37840.58008050298 37107.87957819255 43308.38479094759 46275.08549406471 47043.09821035893 46853.65091102988 42929.252765778205 36795.754885191935 39045.14402892876 38901.04460641806 0.9727394331786114 0.9539044504750995 1.113296191120852 1.189558942754716 1.2093016700789974 1.2044316903330603 1.1035501282835873 0.9458808949084421 1.0037042558617288 1.0 15.247521275847408 -7.745710351662276 19.139695442933547 0.9810947977519119 1.111956065304064 0.31067467020320527 0.0840195053718747 19.68716748972687 23957.41401872309 0.04643885452830324 0.02654817079590097 1.795931005623763e-08 7.745710351662276 0.13086126755215222 RQGS(ph)VVSSR ddPTM_PC-9_AZD4547_30min_R2 1 RQGSVVSSR 9 1 Q9BZ67-2;Q9BZ67-3;Q9BZ67 Q9BZ67-2 FRMD8 FERM domain-containing protein 8 1 RQGS(0.994)VVS(0.006)SR 80.245 0.008696200000000001 9025900.0 4881.5 6066.2 8533.8 12059.0 13218.0 9297.0 9745.9 11624.0 9307.5 6858.9 True False 6433.715458492392 8026.980518993491 8420.636236114136 9278.98385969277 11382.908859288009 8715.65712030256 10613.266219689996 9827.777892946979 9799.475448362145 6618.771998686675 0.9720406534277048 1.2127597869493374 1.2722354294399316 1.4019192474878943 1.7197916564502682 1.3168087859850675 1.60350986886932 1.4848340288647273 1.480557941912276 1.0 12.692347858833113 -5.08080561474376 1.220121816558487 1.4634770380104922 0.9099725918949586 0.36584664991985416 0.18335574882009884 0.8819835311760322 1.6126389519549205 0.05403424143426215 0.5410869454541004 8.302222823888248e-06 5.08080561474376 -0.5535044461155336 RQGS(ph)VVSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RQGSVVSSR 9 1 Q9BZ67-2;Q9BZ67-3;Q9BZ67 Q9BZ67-2 FRMD8 FERM domain-containing protein 8 1 RQGS(0.994)VVS(0.006)SR;RQGS(0.934)VVS(0.066)SR;RQGS(0.981)VVS(0.019)SR;RQGS(1)VVSSR 115.91 0.0028646 21182400.0 52620.0 60855.0 74167.0 69113.0 115062.0 96830.0 73088.0 77235.0 79563.0 68731.0 True False 61527.5267076265 66896.28222331598 75935.42255991371 65240.822677369186 92516.42707947832 91752.0643405271 66164.57552870315 75207.6630872467 80726.458356592 81191.38622570332 0.7578085504857202 0.8239332438215985 0.9352645162236966 0.8035436480417605 1.1394857432572048 1.1300714103521552 0.8149211216171719 0.9263010102842375 0.9942736798726547 1.0 16.30903905636083 -5.36330562313771 1.1605496989086175 0.9835146709763952 0.7521139697659188 0.35782613576386346 0.10232748927923804 0.9047985038563093 1.893336437891253 0.03667629889945141 0.19953791043413255 4.332059140077086e-06 5.36330562313771 -0.2314007012104764 RQGS(ph)VVSSR ddPTM_PC-9_Lapatinib_30min_R1 1 RQGSVVSSR 9 1 Q9BZ67-2;Q9BZ67-3;Q9BZ67 Q9BZ67-2 FRMD8 FERM domain-containing protein 8 1 RQGS(0.971)VVS(0.008)S(0.022)R 56.551 0.039548 1943300.0 5030.3 2893.7 4220.7 3170.5 3416.0 2529.4 3909.8 3952.6 3824.0 4345.4 True False 4958.56699955596 2886.999815438399 3873.690338373155 3403.6691464779547 3215.0775961144 2421.2234583193876 4112.230313201674 4136.25222567572 3393.3008514948156 5096.496600118457 0.9729363891738315 0.5664675250389252 0.7600692480169848 0.6678448772827287 0.6308407222403862 0.47507604699728667 0.8068739441729628 0.8115873609293848 0.6658104807557305 1.0 12.31529014459974 -10.299708980227809 7.692278038903729 1.0000000001162812 0.699743515155143 0.3031733939094796 0.13319686358997526 2.750446016940587e-10 1.2275857812817496e-10 0.12674087570223302 0.03073917727706856 5.0152319063396043e-11 10.299708980227809 -0.3002564849611382 RQGSFS(ph)EDVISHK ddPTM_PC-9_AZD4547_30min_R2 1 RQGSFSEDVISHK 13 1 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;E9PNZ4 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 RQGS(0.311)FS(0.688)EDVISHK 88.385 0.0030388999999999998 5982100.0 37263.0 37277.0 58590.0 82231.0 69963.0 62414.0 50945.0 65002.0 49087.0 60236.0 True False 49111.85888145075 49326.06125853418 57813.05831797408 63273.91340628534 60249.8450992864 58511.24271340902 55479.006306457806 54957.43449736234 51681.63860690334 58127.15597441146 0.8449038673605606 0.8485889328603714 0.9945963697832447 1.088543080176494 1.036518028265642 1.006607698803751 0.9544421256543256 0.9454691800430682 0.8891134916295312 1.0 15.826924702156962 -5.2602184029641945 21.48327515761519 0.9920518082094856 0.8467462703248408 0.5579458902941097 0.05075120633075828 11.662104352047045 205138.52217726404 0.01484797364705334 0.03500347832218152 5.4926458395065965e-06 5.2602184029641945 -0.14530553788464473 RQGSVVSS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 RQGSVVSSR 9 1 Q9BZ67-2;Q9BZ67-3;Q9BZ67 Q9BZ67-2 FRMD8 FERM domain-containing protein 8 1 RQGS(0.214)VVS(0.052)S(0.734)R 79.23 0.0093737 7484300.0 6110.9 6665.0 6851.6 12906.0 8993.5 5851.3 8287.8 9406.1 7853.7 7724.0 True False 8054.039085383822 8819.330908821275 6760.743307244085 9930.721095712322 7744.907764110057 5485.417286009076 9025.398144403984 7952.603375675207 8268.830548353677 7453.585111002628 1.0805590820308515 1.183233407478315 0.907045831845966 1.3323415440783073 1.0390849032739147 0.7359434693932405 1.2108801348603533 1.0669500994811143 1.109376283387121 1.0 12.863718801212416 RQHEAEEGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RQHEAEEGVR 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 86.189 0.0072293999999999995 974700.0 2742.1 2699.9 4369.0 2113.6 5970.4 4898.4 2954.2 3912.3 4347.1 5550.7 False True 3206.2833710563027 2967.9282289825132 4473.17352952477 1995.1818443836544 4800.54297887501 4641.519280859631 2674.356789444167 3809.6062704244987 4410.668113594779 6556.997970682979 0.48898648213586915 0.4526352215224756 0.6821984007810884 0.30428282169741705 0.7321251280446841 0.7078726120722239 0.40786298873379173 0.5809985434580954 0.6726657737756419 1.0 12.67881973302623 -14.52287874430972 0.20606496200103058 3.097120079163757 0.491415794126686 0.5274455536431999 0.1303953680069288 116.48405240500517 1.1550298625989255 100.57642372018807 0.28993021001781366 3.0000000067047882e-15 14.52287874430972 -2.605704285037071 RQILIACS(ph)PVSSVR ddPTM_PC-9_AZD4547_30min_R2 1 RQILIACSPVSSVR 14 1 Q5QJE6;J3KP30;E9PRB3 Q5QJE6 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 RQILIACS(0.682)PVS(0.159)S(0.159)VR 65.905 0.017353999999999998 12844000.0 22183.0 14227.0 26759.0 47605.0 39401.0 24626.0 16910.0 26219.0 23289.0 31853.0 True False 29236.732564936337 18825.599525851492 26404.158175980014 36630.40273991822 33930.85126076614 23086.132327048585 18414.957240989326 22167.456002682116 24520.008994564192 30737.83616529864 0.9511643047256213 0.6124568894379293 0.8590116114220456 1.1917040140018695 1.1038789808852012 0.7510656313898759 0.599097384147646 0.7211781559206819 0.7977142197877274 1.0 14.90772798753615 -6.879862842648902 12.334549410639497 0.7447061002355012 0.9342749767114458 0.18650423125412263 0.17155024549990303 0.7671035895000098 78.80435328142202 0.06571562432653756 0.05796028987459645 1.3186731314972255e-07 6.879862842648902 0.18956887647594456 RQILIACS(ph)PVSSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RQILIACSPVSSVR 14 1 Q5QJE6;J3KP30;E9PRB3 Q5QJE6 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 RQILIACS(0.522)PVS(0.133)S(0.345)VR 55.321999999999996 0.034433 5994400.0 20117.0 10557.0 14765.0 19477.0 23636.0 22745.0 26409.0 24730.0 30018.0 17752.0 True False 23522.41077113878 11605.0291912176 15117.05359657432 18385.766835285976 19004.695472445692 21552.212159715884 23907.34833539739 24080.86370360091 30456.95646152336 20970.29707524532 1.1217013610601703 0.5534031849704657 0.7208793248055345 0.8767528075217262 0.9062673458679825 1.0277494916921084 1.1400576849061024 1.1483320249205007 1.4523855504878231 1.0 14.356059679035809 -6.9021052044319955 1.1541711210905328 1.222006610073719 0.7853825964934512 0.4950097579779783 0.16860130846997448 0.37011407621547143 1.0290625054601397 0.09176236095150084 0.07232053056314189 1.2528376480853704e-07 6.9021052044319955 -0.4366240135802678 RQILIACS(ph)PVSSVR ddPTM_PC-9_Lapatinib_30min_R1 2 RQILIACSPVSSVR 14 1 Q5QJE6;J3KP30;E9PRB3 Q5QJE6 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 RQILIACS(0.966)PVS(0.015)S(0.019)VR;RQILIACS(0.759)PVS(0.12)S(0.12)VR 81.594 0.0046925 12393200.0 72021.0 49744.0 58099.0 53178.0 47596.0 51681.0 37763.0 35956.0 54216.0 42271.0 True False 70993.96733296609 49628.82082426222 53322.32448862558 57088.887516607654 44796.49685733635 49470.72410429519 39718.18336422192 37626.64702383143 48109.62316020999 49577.48602743297 1.4319799776390967 1.0010354457424655 1.07553506160277 1.1515083174047664 0.903565316574319 0.9978465644046834 0.8011334689751 0.7589462483638496 0.9703925514413788 1.0 15.597397496724184 -1.5228787452821086 0.44049262440500475 0.8835478810374551 10.943419458157127 0.6241314359032846 0.1100576278490541 57.071787538889055 0.701925075063704 0.072293964864742 513.1893856952729 0.02999999999987766 1.5228787452821086 10.059871577119672 RQLAELETEDGMQES(ph)P ddPTM_PC-9_Lapatinib_30min_R1 1 RQLAELETEDGMQESP 16 1 Q96QG7-2;Q96QG7 Q96QG7-2 MTMR9 Myotubularin-related protein 9 1 RQLAELETEDGMQES(1)P 88.10799999999999 0.022259 0.0 6170.1 6324.0 8642.5 6807.5 6582.5 9191.0 6562.6 7653.9 7621.1 6494.0 True False 6082.113242542236 6309.357166545399 7931.94701101476 7308.146259154285 6195.330291692929 8797.922355267454 6902.379316951588 8009.528135935687 6762.73146425919 7616.479247288922 0.7985465521628196 0.8283823748080464 1.0414191063197775 0.9595176487555732 0.8134113007526608 1.1551166975737597 0.9062427786970578 1.0516050626392333 0.8879078173378306 1.0 12.894908544024082 -5.16629291481429 6.030407007685671 0.9759014094045004 0.807787841848496 0.34278819166499475 0.09069740352126507 0.24581787896861693 12.70045958503926 0.02202354604984856 0.06034020546341757 6.818786382716568e-06 5.16629291481429 -0.16811356755600448 RQLEEAEEEAQR ddPTM_PC-9_AZD4547_30min_R2 2 RQLEEAEEEAQR 12 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 157.56 8.5091e-05 10504500.0 28664.3 30568.6 39469.0 39086.0 50997.0 38067.0 27725.0 42409.0 29668.0 34208.0 False True 37778.95114552153 40449.302148446215 38945.61527141353 30075.326572680275 43916.946822296166 35686.664472255296 30192.471289558198 35855.66351187097 31236.18991157758 33010.38833210483 1.1444564288502768 1.225350690864383 1.1797987615170311 0.9110867242791565 1.330397763893737 1.0810737551229475 0.9146354470539199 1.0861933265110644 0.9462533308400459 1.0 15.010632489982255 -7.002730192025475 24.997373678747845 0.9945106171544169 1.1550489389830567 0.36512403510212854 0.10633744632293135 127.47918029384402 1167198.518617281 0.03716863547953136 0.03221618687140387 9.93733219236692e-08 7.002730192025475 0.1605383218286398 RQLEEAEEEAQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RQLEEAEEEAQR 12 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 136.24 3.9748e-05 7481400.0 25239.1 20526.0 30429.0 31955.0 36141.0 31020.0 30935.0 32835.0 27383.3 18398.3 False True 29511.581135052376 22563.685628391813 31154.542762625126 30164.664949507816 29059.4304903393 29393.256592410948 28004.61284999501 31973.116041558234 27783.728958386047 21733.766149137333 1.3578677957857646 1.0381857186444154 1.4334626842325588 1.3879170661227127 1.337063732577832 1.35242352341118 1.2885301451127733 1.4711263488416308 1.2783669782647795 1.0 14.407650574036019 -8.55495828235154 22.580755473630063 0.9999999974713676 1.3308377246680951 0.4476735972281425 0.11051755300572495 3343.410777134112 2353419.897990311 0.1071763136422507 0.027672805127639616 2.786388811924717e-09 8.55495828235154 0.33083772719672755 RQLEEAEEEAQR ddPTM_PC-9_Lapatinib_30min_R1 3 RQLEEAEEEAQR 12 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ;; 185.57 9.5634e-05 14694900.0 55818.0 58594.0 70531.0 63699.0 58581.0 67602.0 56945.0 52108.0 59554.0 50219.0 False True 55022.02508423248 58458.32919300464 64732.21343753338 68383.63695363469 55135.38075467734 64710.82004795894 59893.333465975105 54529.12790960645 52846.40138857799 58899.287237388715 0.9341713230326668 0.992513355168343 1.099032203507583 1.1610265617989584 0.9360958908120355 1.0986689836694852 1.0168770502193 0.9258028486801768 0.8972332920699861 1.0 15.845962555111017 -7.685738787396965 4.7075900365166925 0.9335244966032223 1.0400019028707475 0.2598534385623701 0.07193793713103011 0.2677687290148568 10.890752497580202 0.03704949578079124 0.02023982838400459 2.0618696812874547e-08 7.685738787396965 0.10647740626752511 RQLEEAEEESQR ddPTM_PC-9_Lapatinib_30min_R1 1 RQLEEAEEESQR 12 1 P35749-4;P35749-3;P35749;P35749-2 P35749-4 MYH11 Myosin-11 0 193.49 1.1333e-05 6219300.0 17636.0 14394.0 14841.0 14280.0 14711.0 13074.0 18538.0 16637.0 17364.0 10766.0 False True 17384.507405953704 14360.671577364725 13620.8302679167 15330.198836683545 13845.7279029388 12514.855496982555 19497.80693286936 17410.01575635453 15408.283468973856 12626.888755206728 1.3767847126066712 1.137308790452681 1.0787162643133383 1.214091541779213 1.096527273769596 0.9911274059353713 1.544149735605249 1.378804873779811 1.2202755379958672 1.0 13.624211584757424 -7.245879700471387 24.979133223630434 1.3173746390207153 1.1459232783047972 0.1382970596501042 0.15946541826740523 1261.7009667200687 2025507.0367296273 0.05987505033924037 0.04621425111368236 5.677018369837764e-08 7.245879700471387 -0.17145136071591804 RQLLS(ph)LLR ddPTM_PC-9_AZD4547_30min_R2 1 RQLLSLLR 8 1 A0A0B4J229 A0A0B4J229 ADAMTS13 1 RQLLS(1)LLR 70.41199999999999 0.017516 14799000.0 13951.0 13828.0 14916.0 25390.0 20714.0 16657.0 12659.0 14104.0 13635.0 14164.0 True False 18387.12780117328 18297.63057872177 14718.204094058727 19536.727771589623 17838.21864966651 15615.435156811836 13785.626476267527 11924.550877677579 14355.7182635958 13668.122671186069 1.34525627575288 1.3387083960912367 1.0768270411478196 1.4293643861402583 1.3050964699981416 1.142471101004304 1.0085969235064864 0.8724351664487081 1.0503065131145815 1.0 13.738527480652682 -7.061853587300944 2.4112877712397935 0.9686703050520943 1.2958554899180954 0.7140207431716197 0.09419324097889926 0.16317044354186902 1.8764562305366712 0.040853993849704485 0.031101784995778703 8.672542018927297e-08 7.061853587300944 0.3271851848660011 RQLLS(ph)LLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RQLLSLLR 8 1 A0A0B4J229 A0A0B4J229 ADAMTS13 1 RQLLS(1)LLR;RQLLS(1)LLR 65.5 0.02366 22092000.0 24775.5 18316.9 24031.0 32267.0 31340.0 35039.0 27780.0 26035.0 26819.0 24172.6 True False 28969.502811569742 20135.2807798251 24603.99017807502 30459.184601025463 25199.151976072408 33201.493157365774 25148.477290216964 25351.608836362677 27211.177138436764 28554.901029803696 1.014519461346874 0.7051427269458662 0.8616380828073968 1.0666885018874415 0.8824808024994105 1.1627248549281357 0.8807061619288635 0.8878198810740883 0.9529424427013617 1.0 14.801450763826468 -5.6033241071264825 9.235952320631561 0.9712015624628083 0.840865418378389 0.18685392208897178 0.10888411984765459 0.43764151749960056 45.80223215691115 0.02864800325342778 0.04968849053358205 2.4927337447153328e-06 5.6033241071264825 -0.1303361440844193 RQLLS(ph)LLR ddPTM_PC-9_Lapatinib_30min_R1 2 RQLLSLLR 8 1 A0A0B4J229 A0A0B4J229 ADAMTS13 1 RQLLS(1)LLR;RQLLS(1)LLR 84.65799999999999 0.0063311999999999995 27691000.0 61468.0 47577.0 45991.1 35580.9 41230.4 44461.9 41153.5 44700.6 47070.4 30920.6 True False 60591.455048149335 47466.83837962219 42209.88928877998 38197.638080402896 38805.308934085224 42560.36818275113 43284.22686437799 46777.55306356322 41768.835878713806 36265.184510890314 1.6707885501024797 1.3088817558716144 1.1639231912939665 1.0532867430726092 1.0700430580308262 1.1735875263496975 1.1935476807343937 1.2898749501609752 1.1517612950837397 1.0 15.146297568654537 -4.76280678497534 2.0461920459196574 1.1449341325282412 1.8384163722044031 0.8156001251884953 0.07726936052998547 0.3372378721900191 1.5062677874112578 0.022188212340968207 0.44984308433392844 1.726605877798117e-05 4.76280678497534 0.693482239676162 RQLQEDQENNLQDNQT(ph)SNSSPCR ddPTM_PC-9_Lapatinib_30min_R1 1 RQLQEDQENNLQDNQTSNSSPCR 23 1 Q92576-2;Q92576 Q92576-2 PHF3 PHD finger protein 3 1 RQLQEDQENNLQDNQT(0.259)S(0.247)NS(0.247)S(0.247)PCR 61.703 0.032438999999999996 0.0 5135.7 6551.6 6523.5 5093.6 8116.9 6540.3 6054.6 5493.7 6834.6 7444.0 True False 5062.463976227964 6536.430172729105 5987.16301143822 5468.200335751489 7639.479900439391 6260.586615183949 6368.077562614679 5748.95735773787 6064.815376471362 8730.685481493485 0.5798472510502086 0.7486731925671171 0.6857609318454163 0.6263197027704736 0.8750149019378681 0.7170784732143396 0.7293903297871801 0.6584772031845596 0.6946551206462548 1.0 13.091879214797144 -11.72234826373604 2.2261461374346485 1.8188542488067156 0.705481349549618 0.5877721017265437 0.07488610088639641 7120497.642296462 1478171.28253071 29332477.35193815 0.019666444871853598 1.895185549350054e-12 11.72234826373604 -1.1133728992570977 RQLQEDQENNLQDNQTSNSS(ph)PCR ddPTM_PC-9_Lapatinib_30min_R1 1 RQLQEDQENNLQDNQTSNSSPCR 23 1 Q92576-2;Q92576 Q92576-2 PHF3 PHD finger protein 3 1 RQLQEDQENNLQDNQT(0.007)S(0.007)NS(0.122)S(0.864)PCR 106.72 9.351700000000001e-07 4964500.0 12624.0 17324.0 19161.0 15652.0 20794.0 18704.0 18344.0 18581.0 18778.0 15090.0 True False 12443.979445041927 17283.887342383383 17585.656543598943 16803.10029354137 19570.93780257694 17904.07352115355 19293.762562118653 19444.341093275452 16663.02389889374 17698.286393838902 0.7031177577380545 0.9765853573485069 0.9936361155123375 0.9494196172229894 1.105809758474128 1.0116275170790707 1.0901486241535319 1.0986567095017958 0.9415049303696682 1.0 14.11132206015204 -4.264548004658485 1.313781489414015 1.0347339010546825 2.336532730411763e-20 0.7430656944171015 0.05603836130814309 2.22119129205751 1.3256213579728469 0.016135179109404707 4.298738010827584 5.438160177973711e-05 4.264548004658485 -1.0347339010546825 RQLQEQQR ddPTM_PC-9_Lapatinib_30min_R1 1 RQLQEQQR 8 1 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;A0A0U1RQP7;A0A075B6E5;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 0 82.426 0.039195 0.0 1096.7 670.75 393.46 808.73 709.19 394.76 577.95 591.45 1100.4 0.0 False True 1081.0608568898513 669.1969195857573 361.1112375995219 868.2067020441934 667.4768385211858 377.8770350305057 607.8734230689311 618.9309261943794 976.4613642742933 0.0 0.0 RQLS(ph)APHITR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RQLSAPHITR 10 1 A6ND36;A6ND36-2;K7EKG0 A6ND36 FAM83G Protein FAM83G 1 RQLS(0.996)APHIT(0.004)R 55.98 0.040161 10952000.0 6299.7 5867.4 5087.0 6220.5 8679.7 8258.3 5822.8 5807.3 6056.5 5689.8 True False 7366.114785253412 6449.876695704287 5208.293372554932 5871.985552133103 6978.975092747792 7825.220210093726 5271.2222305786645 5654.864528342961 6145.064854727701 6721.315699567981 1.0959334622128933 0.9596151979766192 0.7748919416015082 0.87363632577332 1.038334666112525 1.1642393483461428 0.7842545219111605 0.8413329742428901 0.9142651720886553 1.0 12.714527953298246 RQLS(ph)APHITR ddPTM_PC-9_Lapatinib_30min_R1 1 RQLSAPHITR 10 1 A6ND36;A6ND36-2;K7EKG0 A6ND36 FAM83G Protein FAM83G 1 RQLS(0.987)APHIT(0.013)R 58.11600000000001 0.0359 2654000.0 10142.0 8861.3 11411.0 8935.1 10888.0 10526.0 7605.1 11277.0 13333.0 9648.6 True False 9997.373220184983 8840.782204286648 10472.831627733802 9592.21706061983 10247.589246631607 10075.827517304448 7998.854865959914 11800.970588712507 11831.297137285674 11316.347654048637 0.8834452179991337 0.7812398906924436 0.9254604001130124 0.8476424862387498 0.9055562412811998 0.890378046462688 0.7068406795630896 1.0428250306087483 1.0455049189879566 1.0 13.466120783689249 -7.795669069203161 24.999998827457066 1.0331240428310582 0.8527678929630722 0.6418708858849034 0.061812896276838135 116.6698601870927 85209.49582795406 0.032887977493331076 0.01580007319837884 1.6007773504458585e-08 7.795669069203161 -0.18035614986798598 RQNGWST(ph)MPR ddPTM_PC-9_Lapatinib_30min_R1 1 RQNGWSTMPR 10 1 P15941-17 P15941-17 1 RQNGWS(0.21)T(0.79)MPR 72.325 0.026195 1346800.0 2086.0 2328.4 3158.7 1119.1 2658.7 2698.0 2203.4 1018.2 2154.0 2191.3 True False 2056.253257474451 2323.0087328564705 2899.0038789346045 1201.4023472081617 2502.320493205313 2582.6128293451843 2317.4812706809985 1065.509289121848 1911.3938373744343 2570.0632852762888 0.8000788421260211 0.9038721910720345 1.1279892972063346 0.46746021940039806 0.9736415860033216 1.0048829708360845 0.901721480540065 0.41458484513827953 0.7437146969588938 1.0 11.327588169462622 RQPS(ph)MSETMPLYTLCK ddPTM_PC-9_AZD4547_30min_R2 2 RQPSMSETMPLYTLCK 16 1 K7EJD2;A0A0A0MR03;Q9Y5B0 K7EJD2 CTDP1 RNA polymerase II subunit A C-terminal domain phosphatase 1 RQPS(0.945)MS(0.026)ET(0.029)MPLYTLCK;RQPS(0.354)MS(0.298)ET(0.348)MPLYTLCK 79.393 0.0041056999999999995 8414700.0 36976.0 37282.0 42483.0 48486.0 44477.0 43488.0 45757.0 55711.0 45214.0 39138.0 True False 48733.59885142163 49332.67741075386 41919.64766210092 37308.30180123256 38302.13627890397 40768.68848528746 49829.2843569455 47102.145061421994 47603.91973378956 37767.79053268008 1.2903481555070833 1.3062103108220429 1.1099311627940818 0.9878338466463923 1.0141481865549302 1.0794565398261973 1.3193592649755015 1.2471511941018893 1.2604369771802875 1.0 15.204868766166223 -7.244558635133282 24.704612218489636 1.2273328047079812 1.1264503707476576 0.07075231357272704 0.12454777596276945 1617.3716838449939 2366991.171992472 0.051646391062442405 0.039898412047641066 5.6943133865534835e-08 7.244558635133282 -0.10088243396032359 RQQAMPSTGMAEQS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RQQAMPSTGMAEQSK 15 1 Q96L91-5;Q96L91-2;Q96L91;Q96L91-4;A0A0A0MR80 Q96L91-5 EP400 E1A-binding protein p400 1 RQQAMPSTGMAEQS(1)K 58.37 0.038488 0.0 11615.0 10714.0 10313.0 14177.0 16824.0 13917.0 14575.0 9178.4 12047.0 10966.0 True False 13581.190093293073 11777.615113640748 10558.901032270296 13382.708652454143 13527.457972094528 13187.168020521698 13194.350486137939 8937.47672531866 12223.16458431514 12954.048993191758 1.0484127472754596 0.9091840798062979 0.8151042996533149 1.0330907857062819 1.0442648456250347 1.017995842647535 1.0185502998384888 0.6899369247419025 0.9435786903955089 1.0 13.661115485135596 RQQDPS(ph)PGSNLGGGDDLK ddPTM_PC-9_AZD4547_30min_R2 3 RQQDPSPGSNLGGGDDLK 18 1 Q13951-2;J3KTD8 Q13951-2 CBFB Core-binding factor subunit beta 1 RQQDPS(1)PGSNLGGGDDLK;RQQDPS(0.996)PGS(0.004)NLGGGDDLK;RQQDPS(0.954)PGS(0.046)NLGGGDDLK 81.51 0.0014172 22483100.0 68965.0 67359.0 85164.0 94369.0 101375.0 81070.0 82217.0 92857.0 70616.0 90974.0 True False 90894.43543888719 89131.47947296215 84034.66971483102 72613.68503651608 87300.83110987459 76000.68008421306 89534.15372456648 78508.08429158457 74348.61759457871 87789.02795033056 1.035373526294352 1.0152917916278914 0.9572343113580926 0.8271385016086473 0.9944389765799413 0.8657195763371803 1.0198786319313533 0.8942812800707056 0.8469010231739188 1.0 16.421753019642708 -5.339041128965002 3.5555518455667583 0.9201546005731706 1.0276153557732368 0.2948478819264613 0.06323287607574073 0.27245669899717734 6.58380029486187 0.016267392553327355 0.03932808701739913 4.580985013845353e-06 5.339041128965002 0.10746075520006626 RQQDPS(ph)PGSNLGGGDDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RQQDPSPGSNLGGGDDLK 18 1 Q13951-2;J3KTD8 Q13951-2 CBFB Core-binding factor subunit beta 1 RQQDPS(0.998)PGS(0.002)NLGGGDDLK 66.60600000000001 0.0063248 5800600.0 11104.0 12157.0 10282.0 18348.0 21034.0 19464.0 14912.0 16091.0 13203.0 12276.0 True False 12983.687886003125 13363.866617185973 10527.16187470215 17320.021045018595 16912.5386938324 18443.27357558628 13499.427406469227 15668.628299823775 13396.06889737799 14501.541623237474 0.8953315601423977 0.9215479956814747 0.7259339833106625 1.1943572273215939 1.1662579836844045 1.271814683897643 0.9308960217607178 1.0804801797566228 0.923768606498494 1.0 13.823918657305283 -5.765062090405099 24.99999608579003 1.089673875101679 0.8549988589507738 0.46002014441672356 0.11557390389100401 84.07672116405358 580211.9366582414 0.033531821758155375 0.05201328933965702 1.71766279802952e-06 5.765062090405099 -0.23467501615090525 RQQDPS(ph)PGSNLGGGDDLK ddPTM_PC-9_Lapatinib_30min_R1 3 RQQDPSPGSNLGGGDDLK 18 1 Q13951-2;J3KTD8 Q13951-2 CBFB Core-binding factor subunit beta 1 RQQDPS(0.988)PGS(0.012)NLGGGDDLK;RQQDPS(0.997)PGS(0.003)NLGGGDDLK;RQQDPS(0.998)PGS(0.002)NLGGGDDLK 67.252 0.0060323 24194500.0 67355.0 75138.0 84619.0 65551.0 78345.0 75230.0 68579.0 71684.0 78759.0 62374.0 True False 66394.50534860582 74964.02257746512 77661.952458786 70371.83921172585 73736.90113219636 72012.5882696953 72129.68506037597 75014.70033530785 69888.33205096239 73155.2627918693 0.9075834439622176 1.0247249441334363 1.0616044491527354 0.9619518340319213 1.0079507381715223 0.984380146026883 0.985980807226253 1.0254176866089422 0.9553425055665303 1.0 16.15867403517252 RQQEEMMR ddPTM_PC-9_AZD4547_30min_R2 2 RQQEEMMR 8 1 Q15233;Q15233-2;H7C367 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 ; 60.973 0.018796 18953000.0 1369.45 2129.21 3078.75 5868.1 3878.7 2632.58 1663.22 2931.29 1510.58 1989.48 False True 1804.906613670471 2817.4354935290826 3037.9237633804855 4515.300206241241 3340.209456235466 2467.964356433914 1811.2433579159242 2478.326484843131 1590.426174889809 1919.828910750582 0.9401393028115298 1.4675450909985357 1.5823929655235631 2.3519284353707985 1.7398474611623427 1.2855126530358538 0.9434399845597674 1.29091007587452 0.8284207858230509 1.0 10.906762032790963 -6.952365850164489 4.00089958974136 1.0451324556677264 1.6444085282949736 0.4059060945592825 0.3411189434472881 0.24474933460086737 8.29558836779303 0.13756919599729364 0.11733875422623721 1.1159227970869466e-07 6.952365850164489 0.5992760726272472 RQQEEMMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RQQEEMMR 8 1 Q15233;Q15233-2;H7C367 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 ;;; 69.628 0.011202 22255020.0 10953.4 7548.24 12903.42 15431.000000000002 14703.589999999998 13854.84 15577.27 16567.84 15134.260000000002 9930.46 False True 12807.594280488718 8297.579382619717 13211.086469292855 14566.451097976993 11822.527090103978 13128.267800348129 14101.678215931528 16132.951755077525 15355.569921293032 11730.773788521898 1.0917944980765417 0.707334361075019 1.1261905401516978 1.241729775083524 1.0078215898828309 1.1191305907879345 1.2021098070895773 1.3752674841333132 1.3089988945416249 1.0 13.518010559501057 -5.67970937749718 0.720251048137567 1.2265615576355349 0.8727415103484099 0.26597093353075174 0.1533843314143473 1.3738473270525995 1.160268261321273 0.07893154716518017 0.3302670569362035 2.090694720299927e-06 5.67970937749718 -0.353820047287125 RQQEEMMR ddPTM_PC-9_Lapatinib_30min_R1 5 RQQEEMMR 8 1 Q15233;Q15233-2;H7C367 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 ;;;; 62.582 0.017041 16472740.0 8979.44 3414.59 8788.64 6771.15 6321.159999999999 7226.629999999999 5475.3099999999995 3576.8199999999997 5919.740000000001 4904.18 False True 8851.391538972375 3406.683726646786 8066.071944331471 7269.122958894237 5949.361796678719 6917.5638809973225 5758.794760902412 3743.012115023385 5252.996543574253 5751.860978590908 1.538874387249323 0.5922750461679892 1.4023412551788583 1.2637862747293012 1.0343368552930836 1.202665347223324 1.0012054850312468 0.6507480151129015 0.9132690381646069 1.0 12.48981309119012 -7.525485762779394 6.265149995722115 0.8328807385178667 1.1508467966844869 0.24435435096334046 0.24951476211321166 0.20281238246890781 35.73658601268593 0.10896877949571981 0.06574676172201403 2.982045304960823e-08 7.525485762779394 0.31796605816662016 RQQPPLGPSSS(ph)LLSLPGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RQQPPLGPSSSLLSLPGLK 19 1 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 RQQPPLGPSS(0.001)S(0.998)LLS(0.001)LPGLK;RQQPPLGPS(0.025)S(0.111)S(0.674)LLS(0.19)LPGLK 161.64 1.7916e-06 17138200.0 72013.0 71714.0 85019.0 95852.0 124403.0 105782.0 103993.0 94545.0 99308.0 93724.0 True False 84203.37857841708 78833.2919786853 87046.17539635314 90481.72319637676 100027.12518440776 100234.60570143169 94142.03019587928 92063.293928708 100760.19162772199 110715.41928122399 0.7605388583186892 0.712035346932516 0.7862154699089428 0.8172459065213635 0.9034615578732778 0.9053355562591477 0.8503064054407158 0.8315309152635871 0.9100827353756832 1.0 16.75649663396763 -1.5228787452805572 0.13091195071451134 1.0175587809728162 0.03238059292071413 0.7640629715796846 0.039008994368126895 45.03846109337659 0.3999506127715743 0.2319613312772695 8.195997677506789 0.029999999999984827 1.5228787452805572 -0.985178188052102 RQS(ph)EDPSCPNER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RQSEDPSCPNER 12 1 Q4KMQ2-3;Q4KMQ2;Q4KMQ2-4;Q4KMQ2-2 Q4KMQ2-3 ANO6 Anoctamin-6 1 RQS(1)EDPSCPNER 73.80199999999999 0.009991700000000001 2291600.0 8542.4 9771.5 9875.8 10373.0 17776.0 8886.5 8313.2 8956.3 11316.0 9784.3 True False 9988.459599909316 10741.549942406245 10111.27652618006 9791.834439719747 14292.920406083707 8420.476296210823 7525.71351364405 8721.206614984256 11481.475092231263 11558.116137523819 0.8641944310873846 0.9293512726986223 0.8748204643275261 0.8471825618649238 1.2366133231419307 0.7285336291849032 0.6511193886702318 0.7545526027957584 0.993369071189401 1.0 13.496618651044532 RQS(ph)EDPSCPNER ddPTM_PC-9_Lapatinib_30min_R1 1 RQSEDPSCPNER 12 1 Q4KMQ2-3;Q4KMQ2;Q4KMQ2-4;Q4KMQ2-2 Q4KMQ2-3 ANO6 Anoctamin-6 1 RQS(1)EDPSCPNER 68.97800000000001 0.015236000000000001 3010200.0 16832.0 19619.0 10764.0 8096.1 10254.0 7621.6 7778.6 7409.9 14280.0 4272.7 True False 16591.972593389237 19573.573410887766 9879.025470241579 8691.51420179787 9650.879880139659 7295.641934817361 8181.337847017892 7754.191005169886 12671.63602493358 5011.230501985121 3.3109577751046544 3.9059415453218524 1.9713771829749513 1.7344071876867093 1.925850322853162 1.4558583828716931 1.6326005845823661 1.5473626691285072 2.5286476085891296 1.0 12.290949183719281 -5.326574937331787 5.004235042763679 1.72359622893147 3.608759298395131 0.7883175647479136 0.3915058099966795 0.07873324516357316 3.909861725831374 0.0979730094698309 0.21591395160335355 4.714385177981953e-06 5.326574937331787 1.885163069463661 RQS(ph)FASLALR ddPTM_PC-9_AZD4547_30min_R2 2 RQSFASLALR 10 1 Q12955;A0A087WTF3;A0A087WZ65;Q12955-7;Q12955-6;Q12955-5;Q12955-4;H0Y3A4;H0YA66 Q12955;Q12955-6 ANK3 Ankyrin-3 1 RQS(0.997)FAS(0.003)LALR;RQS(0.968)FAS(0.032)LALR 122.52 0.00024384 23147000.0 15769.3 15565.599999999999 17634.3 28378.0 29420.0 18595.6 17120.2 26195.0 22714.0 18578.7 True False 20783.60937818375 20596.87579810179 17400.457659953063 21835.89053572945 25335.540826165336 17432.81419235219 18643.864633777983 22147.164651216972 23914.61566844996 17928.265367916167 1.1592649345417105 1.1488493379265392 0.9705600236759295 1.21795890944398 1.413161859568689 0.9723648013125342 1.039914584661516 1.23532110869191 1.3339057169048136 1.0 14.129948287936056 RQS(ph)FASLALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RQSFASLALR 10 1 Q12955;A0A087WTF3;A0A087WZ65;Q12955-7;Q12955-6;Q12955-5;Q12955-4;H0Y3A4;H0YA66 Q12955;Q12955-6 ANK3 Ankyrin-3 1 RQS(1)FASLALR 79.089 0.0089412 2135000.0 6573.0 4182.7 4732.1 4644.5 5615.6 4621.9 4703.9 5160.3 3601.7 3196.9 True False 7685.67907733236 4597.930813498709 4844.931210589187 4384.283722672167 4515.263491921901 4379.519427610062 4258.31253871316 5024.8475927898 3654.368048753035 3776.4726633535247 2.0351475470518676 1.217519951386521 1.2829250050195957 1.160946765275643 1.19562986268576 1.1596851925100469 1.1275899280392936 1.3305663884583008 0.9676670201308805 1.0 11.882823628387394 -4.757597350074322 4.844767814960621 1.1707455429373372 2.0985984923024774 0.8610817537474872 0.10550445317912356 0.061379411210223334 3.5626028449878757 0.024558378041801502 0.19663870576432382 1.7474415175626414e-05 4.757597350074322 0.9278529493651402 RQS(ph)FAVLR ddPTM_PC-9_AZD4547_30min_R2 4 RQSFAVLR 8 1 Q8TE77;C9JUG3;Q8TE77-4;Q8TE77-2;A0A087WWG1 Q8TE77 SSH3 Protein phosphatase Slingshot homolog 3 1 RQS(1)FAVLR;RQS(1)FAVLR;RQS(1)FAVLR;RQS(1)FAVLR 93.096 0.0034296999999999995 110384000.0 50283.4 54255.2 70858.0 106766.0 97021.0 65436.0 42763.3 74053.0 58847.9 58238.4 True False 66272.4752403065 71792.13238173728 69918.37662220522 82152.74821825666 83551.30885436408 61344.276575682255 46569.150856510874 62609.81041865133 61958.47985363101 56199.49134238932 1.1792362111704644 1.2774516399864098 1.2441104884070049 1.4618059035045339 1.4866915493120172 1.0915450497932246 0.8286400774126826 1.1140636493879958 1.1024740326590445 1.0 15.778269452324238 -6.92253136029845 6.690552334399052 1.0124322223736526 1.3281583495156646 0.6470948436628591 0.11288641628975865 0.14578496565569113 10.200618840592105 0.04293141105438531 0.037801904744116516 1.1952772118819161e-07 6.92253136029845 0.315726127142012 RQS(ph)FAVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RQSFAVLR 8 1 Q8TE77;C9JUG3;Q8TE77-4;Q8TE77-2;A0A087WWG1 Q8TE77 SSH3 Protein phosphatase Slingshot homolog 3 1 RQS(1)FAVLR;RQS(1)FAVLR;RQS(1)FAVLR;RQS(1)FAVLR;RQS(1)FAVLR 84.507 0.0063831 95301300.0 76036.2 85729.0 87436.0 106442.0 105140.0 92236.0 78282.6 83543.0 77623.1 68870.5 True False 88907.62687659507 94239.60855677679 89520.80584287668 100478.39982961991 84538.57175380536 87398.98178780185 70867.10541105611 81350.08477112542 78758.19098902219 81356.17647142209 1.0928196325429032 1.15835837725093 1.1003566013739912 1.23504328973615 1.0391168245658784 1.0742759256699141 0.8710722219836564 0.9999251230753351 0.9680665243245238 1.0 16.31196425742555 -6.797223687025077 1.9740414114897684 0.9627397509448592 1.1409117892707148 0.6421205828665877 0.058198608817878784 0.19382763734572336 1.5553271447413899 0.022617922877016257 0.02024515581354634 1.5950573879066958e-07 6.797223687025077 0.1781720383258556 RQS(ph)FAVLR ddPTM_PC-9_Lapatinib_30min_R1 3 RQSFAVLR 8 1 Q8TE77;C9JUG3;Q8TE77-4;Q8TE77-2;A0A087WWG1 Q8TE77 SSH3 Protein phosphatase Slingshot homolog 3 1 RQS(1)FAVLR;RQS(1)FAVLR;RQS(1)FAVLR 86.344 0.005751300000000001 50284000.0 115609.0 197701.9 183067.0 189462.8 208096.4 195142.3 191472.0 198031.0 215098.0 189349.1 True False 113960.39445990598 197244.1333973183 168015.93791905587 203396.5263413733 195856.5788852637 186796.51872791958 201385.4832803087 207232.24320770876 190871.39815764426 222077.8396431834 0.5131551830790874 0.8881756672085523 0.7565632761423211 0.9158794351934182 0.8819276124081094 0.8411308351524359 0.9068238578143524 0.933151383049622 0.8594797142493861 1.0 17.760705913103116 -4.451405315047226 2.003533055866639 0.8857562416948024 7.675269079781351e-18 0.758456540756838 0.06251962522481172 1.241265013551965 2.2874124401788976 0.015923599052174105 2.798413986973632 3.536671192578113e-05 4.451405315047226 -0.8857562416948024 RQS(ph)GLYDSQNPPTVNNCAQDR ddPTM_PC-9_AZD4547_30min_R2 4 RQSGLYDSQNPPTVNNCAQDR 21 1 H0Y7W6;B7ZL14;Q96RU3-4;Q96RU3-3;Q96RU3-5;Q96RU3-2;Q96RU3 H0Y7W6;Q96RU3-5 FNBP1 Formin-binding protein 1 1 RQS(0.992)GLY(0.004)DS(0.004)QNPPTVNNCAQDR;RQS(0.985)GLY(0.015)DSQNPPTVNNCAQDR;RQS(0.76)GLY(0.231)DS(0.008)QNPPTVNNCAQDR;RQS(0.992)GLY(0.006)DS(0.002)QNPPTVNNCAQDR 97.295 0.00013436 37764000.0 40782.4 41457.7 40504.700000000004 38046.8 54097.5 53905.9 38969.4 57938.6 48720.299999999996 42694.399999999994 True False 53750.35487338317 54858.090775489785 39967.58121269917 29275.698077200337 46586.99591582188 50535.155551394804 42437.60110626903 48985.5206665776 51295.55559353623 41199.68205116395 1.3046303320164734 1.3315173332494192 0.9700944090555191 0.7105806797451548 1.1307610543685185 1.2265909112754212 1.0300468108847967 1.1889781238055377 1.2450473654101186 1.0 15.330345583341948 -6.499593917271505 24.96169992646979 1.1471315467710126 1.0683388983554936 0.02216703276664822 0.17769311029621138 3296.953770394696 3534387.59967439 0.061035474683813755 0.06875855323487542 3.1652358992096773e-07 6.499593917271505 -0.07879264841551903 RQS(ph)GLYDSQNPPTVNNCAQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RQSGLYDSQNPPTVNNCAQDR 21 1 H0Y7W6;B7ZL14;Q96RU3-4;Q96RU3-3;Q96RU3-5;Q96RU3-2;Q96RU3 H0Y7W6;Q96RU3-5 FNBP1 Formin-binding protein 1 1 RQS(0.787)GLY(0.143)DS(0.07)QNPPTVNNCAQDR;RQS(0.991)GLY(0.007)DS(0.002)QNPPTVNNCAQDR;RQS(0.671)GLY(0.326)DS(0.003)QNPPTVNNCAQDR;RQS(0.984)GLY(0.015)DS(0.001)QNPPTVNNCAQDR 100.71 8.7755e-05 37143200.0 46053.6 42883.0 51378.0 36184.0 41936.9 34432.200000000004 35208.6 37722.5 27412.799999999996 35108.0 True False 53849.56487993817 47140.14083612618 52603.046372150035 34156.727790110774 33719.665491555585 32626.514817576164 31873.38651981039 36732.324345292545 27813.660340077535 41472.8024852249 1.2984308185858096 1.1366519263539117 1.268374530293447 0.8235934333658654 0.8130549051651031 0.7866966508761901 0.768537079961394 0.8856967010700278 0.6706482001062366 1.0 15.33987791883402 -5.766087836259467 24.995808632104296 0.8124443721312459 1.2247024155448443 0.820198374098459 0.08857803226952461 40.442718235361376 217471.171991762 0.022825548194764504 0.035151545587345734 1.7136106939042571e-06 5.766087836259467 0.4122580434135984 RQS(ph)GLYDSQNPPTVNNCAQDR ddPTM_PC-9_Lapatinib_30min_R1 4 RQSGLYDSQNPPTVNNCAQDR 21 1 H0Y7W6;B7ZL14;Q96RU3-4;Q96RU3-3;Q96RU3-5;Q96RU3-2;Q96RU3 H0Y7W6;Q96RU3-5 FNBP1 Formin-binding protein 1 1 RQS(0.931)GLY(0.053)DS(0.015)QNPPTVNNCAQDR;RQS(0.996)GLY(0.003)DSQNPPTVNNCAQDR;RQS(1)GLYDSQNPPTVNNCAQDR;RQS(0.999)GLYDS(0.001)QNPPTVNNCAQDR 135.17 4.1725e-06 39434400.0 32114.600000000002 33980.1 30019.199999999997 30366.4 39002.1 29075.0 27460.200000000004 28182.100000000002 33595.0 34558.5 True False 31656.639914903655 33901.42116618113 27551.137253463025 32599.64635534083 36708.07315907888 27831.530027135363 28881.954792209486 29491.543249814225 29811.177328966616 40531.89067869327 0.781030427764991 0.8364135153458895 0.6797397504071049 0.8042962173604635 0.9056590389546153 0.6866575815020095 0.7125735885642289 0.7276133127763834 0.7354993026426399 1.0 15.306769853457649 -10.644428696128703 5.163430578782463 1.0000068847057992 0.7635706238488293 0.5280066104834591 0.06714423251138306 5.536158127699333e-06 9.419094557814612e-07 0.06763514423042727 0.016403454465174026 2.2676253526410118e-11 10.644428696128703 -0.2364362608569699 RQS(ph)ILFSTEV ddPTM_PC-9_AZD4547_30min_R2 1 RQSILFSTEV 10 1 P11274-2;P11274 P11274-2 BCR Breakpoint cluster region protein 1 RQS(1)ILFSTEV 95.477 0.0086695 3921800.0 19515.0 13065.0 18849.0 23205.0 26734.0 18265.0 15593.0 19890.0 14441.0 19707.0 True False 25720.364062783767 17288.00574999998 18599.049944282193 17855.445763676154 23022.445562430457 17122.88666261442 16980.74679235638 16816.457526730497 15204.321778114181 19017.06392834396 1.3524886996067191 0.9090785946316924 0.978019005161005 0.9389170605386422 1.2106204011922514 0.9003959142764217 0.8929215811830684 0.8842825364680207 0.7995094214019504 1.0 14.215006903193196 -6.951524078095471 21.44490646938242 0.8862671331392542 1.0552215073519722 0.3162055460225356 0.1318603759071121 36.945148039683886 16343.082686958345 0.04561130035678401 0.04022531357601374 1.1180878339925033e-07 6.951524078095471 0.16895437421271797 RQS(ph)IPEEFK ddPTM_PC-9_AZD4547_30min_R2 1 RQSIPEEFK 9 1 F5H4N6;Q9Y3R0-3;Q9Y3R0-2;Q9Y3R0;F5H3G9 F5H4N6 GRIP1 Glutamate receptor-interacting protein 1 1 RQS(1)IPEEFK 73.881 0.036969999999999996 0.0 24201.0 29271.0 33869.0 28782.0 31719.0 40208.0 29551.0 38998.0 31372.0 32700.0 True False 31896.41458792876 38732.27832439723 33419.87493038851 22146.75457746722 27315.364359793948 37693.78740379963 32180.981752127496 32971.75518488871 33030.25987279262 31555.18295310535 1.0108138062558698 1.2274458488153237 1.0590930491531076 0.701842059048742 0.8656379650971359 1.1945355366760813 1.0198318862531126 1.044891903618133 1.0467459473101268 1.0 14.945589367534572 -5.525779949487505 24.999541092598736 0.981011102242787 1.1251647767543254 0.15442714720775463 0.13063155049934178 154.07836906681544 1327680.9727519846 0.038153738761613376 0.0665446271926981 2.9800259815163546e-06 5.525779949487505 0.14415367451153838 RQS(ph)IPEEFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RQSIPEEFK 9 1 F5H4N6;Q9Y3R0-3;Q9Y3R0-2;Q9Y3R0;F5H3G9 F5H4N6 GRIP1 Glutamate receptor-interacting protein 1 1 RQS(1)IPEEFK;RQS(1)IPEEFK 60.301 0.032363 11639500.0 85890.0 100875.0 92957.0 91365.0 100683.0 75849.0 94887.0 74252.0 73384.0 76052.0 True False 100429.48059517352 110889.20334035007 95173.44742138556 86246.11525932656 80954.88890896301 71871.34491546675 85898.6164376102 72302.96367649717 74457.10217111178 89839.62557269938 1.1178751019382276 1.2343017085552865 1.059370481729913 0.960000831587784 0.9011044780396293 0.7999960424735689 0.956132841049075 0.8048003674947273 0.8287779662534338 1.0 16.455064294537124 -5.736382434508539 1.7170387711949928 0.8714956988812073 1.1795087154410127 0.7527559746469182 0.06701496746723885 0.16124644042352967 0.9644038847749786 0.020154325931570242 0.04398130456642009 1.8349218215738719e-06 5.736382434508539 0.3080130165598054 RQS(ph)IPEEFK ddPTM_PC-9_Lapatinib_30min_R1 2 RQSIPEEFK 9 1 F5H4N6;Q9Y3R0-3;Q9Y3R0-2;Q9Y3R0;F5H3G9 F5H4N6 GRIP1 Glutamate receptor-interacting protein 1 1 RQS(1)IPEEFK;RQS(1)IPEEFK 67.749 0.020589 8366400.0 53713.0 87735.0 82854.0 75321.0 88805.0 88962.0 79442.0 75117.0 77770.0 72276.0 True False 52947.04277024216 87531.85499792255 76042.06394568903 80860.35760349009 83581.66449734758 85157.30264055078 83555.11804730864 78607.21004809056 69010.72364559417 84768.81029828383 0.6246052360996045 1.032595062852907 0.8970523908276264 0.9538927975862737 0.9859954882372546 1.0045829632491 0.9856823252950648 0.9273128851459413 0.8141051337486014 1.0 16.371245919042146 -4.753116507096343 24.99994253717221 0.954943001769775 0.6246046241553073 0.7305561680756419 0.060319526755110764 164.7536347902197 494842.9008059083 0.015105411861229535 0.16805455134894204 1.765564113672273e-05 4.753116507096343 -0.3303383776144677 RQS(ph)LELQK ddPTM_PC-9_AZD4547_30min_R2 2 RQSLELQK 8 1 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 RQS(1)LELQK;RQS(1)LELQK 113.67 0.0017008 46174000.0 76779.0 92428.0 118442.0 120487.0 104137.0 106911.0 93159.0 113875.0 92374.0 92250.0 True False 101193.12489759023 122303.54347194797 116871.38169137193 92710.58365559344 89679.37508546513 100225.83826919072 101449.9705271038 96278.2353371763 97256.70105474126 89020.35557871478 1.1367414142500463 1.3738828909058118 1.3128613217909508 1.0414537557493313 1.0074030203818678 1.1258755103552431 1.1396266603024108 1.081530563557948 1.0925220464744565 1.0 16.44184764298425 -5.760450074092562 24.99999978141325 1.0758195893441667 1.2844340125479126 0.640354083986398 0.07008660220487284 16.00323921107493 404381.6052807009 0.01942303070361154 0.03132373489407141 1.7360008197118546e-06 5.760450074092562 0.2086144232037459 RQS(ph)LELQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RQSLELQK 8 1 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 RQS(1)LELQK;RQS(1)LELQK 99.215 0.0024149 17305200.0 98945.0 92735.0 107835.0 128695.0 142370.0 144749.0 150732.0 155058.0 130960.0 134405.0 True False 115694.43424717027 101941.11793573566 110406.19536651461 121484.63638481965 114473.62051159664 137158.10762394874 136453.5737548227 150987.89179753096 132875.04224802082 158771.56255060562 0.7286848626327194 0.6420615650440785 0.695377645674581 0.7651536234399569 0.7209957417601796 0.8638707424714802 0.8594333365669972 0.9509756619634341 0.8368944672045364 1.0 17.27659301008446 -6.918125446681905 0.5477767667777769 0.9629343512878581 0.6614537798544572 0.8083623044076089 0.04791396423455482 0.3634062611653567 0.23368121081883697 0.040643546276904495 0.043197911164459 1.2074650064581702e-07 6.918125446681905 -0.3014805714334009 RQS(ph)LELQK ddPTM_PC-9_Lapatinib_30min_R1 2 RQSLELQK 8 1 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 RQS(1)LELQK;RQS(1)LELQK 119.03 0.0015941 44445000.0 147013.0 101994.0 104084.0 89515.0 80328.0 89665.0 90687.0 73497.0 87903.0 73453.0 True False 144916.5676611179 101757.83915949267 95526.6152958589 96098.23171328608 75603.26497092437 85830.23696932386 95382.32912510104 76911.93893398979 78002.43848037365 86149.25318002951 1.6821569811903072 1.1811807462433281 1.1088501846467913 1.1154853717938307 0.8775846821670437 0.9962969358534195 1.1071753451626192 0.8927754576498053 0.905433716498608 1.0 16.39455066946296 -1.5228787511204054 0.7955272164113848 0.973464547803373 170.4224357740328 0.8806547441240898 0.07686994082179997 156.56749958514146 0.5555909359514867 0.02835510091948051 47790.47299411883 0.029999999596582408 1.5228787511204054 169.44897122622945 RQS(ph)LPASPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RQSLPASPR 9 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;H0YF21 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 RQS(0.963)LPAS(0.037)PR 82.831 0.022333000000000002 3508200.0 13245.0 12737.0 14296.0 13151.0 15479.0 16079.0 10317.0 12793.0 13574.0 9209.0 True False 15487.116899325603 14001.445184099504 14636.870857881917 12414.19210611726 12446.001066931245 15235.788934538221 9339.699071388348 12457.19730530394 13772.494070514962 10878.518801596108 1.4236420584255751 1.287072756821011 1.3454838038919765 1.141165661661203 1.1440896774572982 1.4005389164104591 0.8585451054253835 1.145118883599871 1.266026590724304 1.0 13.409194514900149 -1.5228787453015844 0.2238806059873225 1.0505551640967823 3.0201246286022254 0.3663901189283363 0.13543998346366068 57.532740601078515 0.7425430762464605 0.20601819016988068 41.165622536270966 0.02999999999853232 1.5228787453015844 1.9695694645054431 RQS(ph)LTSPDSQSAR ddPTM_PC-9_AZD4547_30min_R2 3 RQSLTSPDSQSAR 13 1 Q15751 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 RQS(0.956)LT(0.021)S(0.021)PDSQS(0.002)AR;RQS(0.629)LT(0.367)S(0.004)PDSQSAR;RQS(0.917)LT(0.041)S(0.041)PDSQSAR 141.82 0.00011579 16703000.0 17509.9 20815.3 22973.2 25619.7 20993.3 21633.100000000002 18491.0 25877.5 21551.2 24354.0 True False 23077.683971454662 27543.438659623014 22668.56035757777 19713.473985419245 18078.742665735434 20280.37883717515 20136.66317818649 21878.726980792788 22690.352434353204 23501.37387278069 0.9819716964795516 1.1719927017340823 0.9645631987427133 0.8388221936357264 0.7692632253586779 0.8629443941004616 0.8568291916545692 0.9309552326271763 0.9654904669481128 1.0 14.520457477680615 -5.504525326822011 5.512800291388805 0.8799123728059164 1.0768517667734934 0.49077121715836103 0.0756665494262466 0.13059672378134488 12.71306340137372 0.02054816826657459 0.0406378319506618 3.1294979627997942e-06 5.504525326822011 0.19693939396757698 RQS(ph)LTSPDSQSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RQSLTSPDSQSAR 13 1 Q15751 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 RQS(0.896)LT(0.041)S(0.041)PDS(0.023)QSAR;RQS(0.963)LT(0.018)S(0.018)PDSQSAR;RQS(0.767)LT(0.008)S(0.008)PDS(0.204)QS(0.012)AR;RQS(0.961)LT(0.033)S(0.006)PDSQSAR 120.54 0.00030993 28324700.0 39871.0 45264.9 42509.4 35599.0 38934.9 20941.1 29894.399999999998 28281.2 23932.199999999997 26008.3 True False 46620.372811854366 49758.50012669751 43522.985313797275 33604.5034435152 31305.885841518255 19842.911851300352 27062.58601528659 27538.848466408315 24282.163149725802 30723.398908410494 1.5174223708397085 1.6195636516334844 1.416607109244118 1.093775579443328 1.0189590655267085 0.6458566615775176 0.8808460970077838 0.8963477168819882 0.7903475530852997 1.0 14.907050208793999 -5.870998725654608 1.5211513570123687 0.8450790507918478 1.584164826940412 0.897893799724524 0.09855231052557666 0.11009427602127886 0.5181409897014674 0.03256739490047954 0.06484843954572067 1.345864303204576e-06 5.870998725654608 0.7390857761485643 RQS(ph)LTSPDSQSAR ddPTM_PC-9_Lapatinib_30min_R1 3 RQSLTSPDSQSAR 13 1 Q15751 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 RQS(0.976)LT(0.019)S(0.004)PDSQSAR;RQS(0.936)LT(0.061)S(0.003)PDSQSAR;RQS(0.999)LT(0.001)S(0.001)PDSQSAR 193.98 1.9969e-06 14704600.0 31802.9 48750.5 42627.3 38952.4 38707.9 33069.9 32820.6 37554.7 40496.0 28646.7 True False 31349.384814062425 48637.6212124718 39122.64794013646 41817.08943739722 36431.17742465944 31655.5774667021 34519.89007557083 39299.628462172695 35934.914038215 33598.24392567163 0.9330661710598837 1.4476239091564227 1.1644253796920547 1.2446212822880829 1.0843179037944668 0.9421795239278805 1.0274313786142553 1.169692932437602 1.069547388182332 1.0 15.036098209400738 -6.364383842985225 4.896205748290577 1.0480969165871517 1.2125055139279926 0.2417501629513613 0.12894881428128502 0.3095803991234742 11.68959949227165 0.03940483021820421 0.04489799872670495 4.321317307254119e-07 6.364383842985225 0.1644085973408409 RQS(ph)NLQEVLER ddPTM_PC-9_AZD4547_30min_R2 1 RQSNLQEVLER 11 1 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 1 RQS(1)NLQEVLER 56.46 0.036898 6986500.0 13876.0 14573.0 45820.0 71010.0 51771.0 26120.0 11077.0 56434.0 13409.0 26559.0 True False 18288.279361270175 19283.437259452716 45212.39686174382 54639.74159356361 44583.49028250868 24486.71227087263 12062.83154100762 47713.42202430915 14117.772364983944 25629.17749393043 0.7135726211112805 0.7524017212030886 1.7640986283095172 2.131935041867947 1.739559932934526 0.9554232583808684 0.470667915264326 1.86168370153934 0.550847656672843 1.0 14.645499559136084 -6.784870035885071 24.661970480090716 0.9905134759921417 1.44184109311017 0.14893346987626344 0.5383513971630163 446.33122046548635 469782.7133562144 0.20420227761848567 0.18019942502718053 1.64108079878928e-07 6.784870035885071 0.45132761711802827 RQS(ph)NLQEVLER ddPTM_PC-9_Lapatinib_30min_R1 2 RQSNLQEVLER 11 1 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 1 RQS(1)NLQEVLER;RQS(1)NLQEVLER 75.02 0.010172 13240800.0 36228.0 27393.0 57664.0 37521.0 36010.0 42040.0 31145.0 33215.0 49747.0 38560.0 True False 35711.382076598464 27329.57319152091 52923.088509476984 40280.41950638677 33891.96259838395 40242.04720002651 32757.535706344628 34758.290157318974 44143.96900086628 45225.044622029694 0.78963729886964 0.6043017407706067 1.1702163912005843 0.8906662191940804 0.749406946563293 0.8898177444898329 0.7243229051539292 0.7685628714755932 0.9760956427970707 1.0 15.464834305855318 -8.335676423787492 6.483485491386097 0.9934258750728068 0.8264611962359308 0.18045008045009636 0.14034551902370343 0.4823195806780836 33.88306867494825 0.13715330111555585 0.03574845772856599 4.616614127203816e-09 8.335676423787492 -0.16696467883687593 RQS(ph)PEPSPVTLGR ddPTM_PC-9_AZD4547_30min_R2 3 RQSPEPSPVTLGR 13 1 Q9NRL2;Q9NRL2-2 Q9NRL2 BAZ1A Bromodomain adjacent to zinc finger domain protein 1A 1 RQS(0.993)PEPS(0.007)PVTLGR;RQS(0.962)PEPS(0.038)PVTLGR;RQS(0.999)PEPS(0.001)PVTLGR 91.59200000000001 0.0023094 60203000.0 94535.0 90621.0 118935.0 148454.0 123448.0 121443.0 120012.0 142451.0 104133.0 119509.0 True False 124595.16354984671 119912.46605975891 117357.84418925164 114230.22389143628 106309.37606758862 113849.15001192871 130692.83550594957 120438.4711483302 109637.25778826696 115325.02628570865 1.0803827023734816 1.0397783544630221 1.0176268583586259 0.9905068099307424 0.9218239916478799 0.9872024631486008 1.1332564987426788 1.0443394207424967 0.9506805358678116 1.0 16.815346095669838 -4.9248093535491 1.9802315132280923 1.007350905683778 1.0897112750397857 0.16340994791558927 0.053437357120928376 1.1920539244036972 6.4547300790178115 0.016083154105757516 0.16312683046094614 1.1890240702904182e-05 4.9248093535491 0.08236036935600777 RQS(ph)PEPSPVTLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RQSPEPSPVTLGR 13 1 Q9NRL2;Q9NRL2-2 Q9NRL2 BAZ1A Bromodomain adjacent to zinc finger domain protein 1A 1 RQS(0.99)PEPS(0.009)PVT(0.001)LGR;RQS(0.998)PEPS(0.002)PVTLGR;RQS(1)PEPSPVTLGR 85.469 0.0037023000000000004 51744000.0 61644.0 75919.0 79648.0 74479.0 74432.0 67796.0 73823.0 84567.0 69217.0 59503.0 True False 72079.11167550216 83455.73658880839 81547.11038672195 70306.18309417591 59847.583914582785 64240.65841196305 66829.9510077641 82347.20585614299 70229.16767930104 70290.42287451116 1.025447119647926 1.1872988264390034 1.1601453946621896 1.0002242157469003 0.8514329757473237 0.9139318812557338 0.9507689422650791 1.1715281042362868 0.9991285413758361 1.0 16.101040513901516 -5.817873760277547 6.365014228113312 0.9802385249273312 1.1303991965197915 0.3569469810167869 0.08634784441700631 0.2249200883554815 18.693575335357824 0.026743682737527374 0.04044307413908009 1.5209895832402737e-06 5.817873760277547 0.15016067159246027 RQS(ph)PEPSPVTLGR ddPTM_PC-9_Lapatinib_30min_R1 4 RQSPEPSPVTLGR 13 1 Q9NRL2;Q9NRL2-2 Q9NRL2 BAZ1A Bromodomain adjacent to zinc finger domain protein 1A 1 RQS(0.979)PEPS(0.02)PVT(0.001)LGR;RQS(1)PEPSPVTLGR;RQS(0.999)PEPS(0.001)PVTLGR;RQS(1)PEPSPVTLGR 114.01 0.00014269999999999997 78229000.0 125802.0 148383.0 150627.0 139237.0 167005.0 138778.0 158192.0 126546.0 151123.0 129123.0 True False 124008.04041073896 148039.42828012453 138243.02949703476 149476.95346101577 157182.094244463 132842.78844731866 166382.40772059935 132425.7891388854 134101.9363442603 151441.7385044177 0.8188498206333092 0.9775338670970557 0.9128462923251642 0.9870261325391175 1.0379047136987127 0.8771874237526895 1.0986562183168929 0.8744338941607065 0.8855018284166647 1.0 17.208403352379932 -4.7572698067744605 24.893753479484502 0.9606664353221784 0.8188496008873809 0.2678115736171983 0.07062201507578211 161.56680214626567 964472.3166857874 0.01702197967267702 0.12814052217073277 1.748759928631747e-05 4.7572698067744605 -0.14181683443479753 RQS(ph)PLPPQK ddPTM_PC-9_AZD4547_30min_R2 6 RQSPLPPQK 9 1 Q01105;B2REB7 Q01105 SET Protein SET 1 RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK 139.31 0.0012323 226628200.0 527680.0 500911.0 681502.0 966120.0 817715.0 699252.0 556787.0 770470.0 649928.0 726448.0 True False 695471.2635741587 662820.6849015119 672464.8381945029 743395.9604052053 704189.3870383323 655527.661900162 606339.9643606574 651411.5651392689 684281.86722569 701015.276633561 0.9920914518638938 0.9455153218408185 0.959272730009303 1.0604561486522321 1.0045278762254857 0.9351118067614145 0.8649454363854143 0.9292401847039614 0.9761297507120976 1.0 19.41908635844922 -6.771959207066785 22.670469592941306 0.9319041368371768 0.9917130399167494 0.24295611811314133 0.04378400027900505 90.90089986598551 195890.3560531435 0.01615103701577448 0.014426296418659853 1.690599720864842e-07 6.771959207066785 0.05980890307957265 RQS(ph)PLPPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 10 RQSPLPPQK 9 1 Q01105;B2REB7 Q01105 SET Protein SET 1 RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK 114.71 0.0011577999999999998 374385000.0 1047390.0 1105132.0 1129936.0 1296575.0 1409321.0 1222343.0 1221060.0 1095637.0 1051000.0 938956.0 True False 1224692.440104542 1214842.2013970553 1156877.9595461416 1223932.106302865 1133174.6669454488 1158241.181268129 1105392.3570911554 1066877.6896733614 1066368.8867033452 1109181.290028393 1.1041409110617004 1.0952602719848958 1.043001689576397 1.10345542005269 1.021631609848415 1.0442307237606578 0.9965840273620729 0.9618605175408713 0.9614017981461336 1.0 20.081063755247207 -6.877008614590954 0.8827771203724327 0.968878776417885 1.088885329146512 0.7917642517854337 0.023649420757768755 0.2504979570915782 0.41631613365870557 0.015383182432949614 0.012723382744626232 1.3273681280217777e-07 6.877008614590954 0.12000655272862693 RQS(ph)PLPPQK ddPTM_PC-9_Lapatinib_30min_R1 9 RQSPLPPQK 9 1 Q01105;B2REB7 Q01105 SET Protein SET 1 RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK 127.87 0.0019809000000000003 396282200.0 1062423.0 907921.0 1059971.0 858237.0 942617.0 961629.0 848030.0 825987.0 993785.0 734439.0 True False 1047272.6531954819 905818.764707002 972824.2759863841 921354.6119747034 887174.1213163257 920502.3693366852 891936.8439573427 864365.371433795 881854.4682800142 861385.8025715468 1.2157997613485108 1.0515831140968506 1.1293711517907 1.0696189898000734 1.0299381748199141 1.0686296042826038 1.0354673147555835 1.003459041063079 1.023762483253568 1.0 19.716300019599565 -1.5228787452803376 0.32568007308667296 1.0103319924460832 2.697035823292491 0.7171834990136032 0.033152835115433626 31.579621518399982 0.4501652491893739 0.029552727598272127 31.91689764626594 0.029999999999999995 1.5228787452803376 1.686703830846408 RQS(ph)PLPPQKK ddPTM_PC-9_AZD4547_30min_R2 1 RQSPLPPQKK 10 2 Q01105;B2REB7 Q01105 SET Protein SET 1 RQS(1)PLPPQKK 62.693999999999996 0.018668 8957300.0 79469.0 88108.0 94477.0 126770.0 125500.0 105850.0 89624.0 109940.0 92571.0 99092.0 True False 104738.48894211459 116587.18795415216 93224.17324982492 97545.13507697581 108076.49128768704 99231.18276691681 97600.36237530602 92951.29916987209 97464.114072558 95622.81924125743 1.0953294388639414 1.2192402282137427 0.9749155482920797 1.0201031077202227 1.1302374490236358 1.0377353810972194 1.0206806612662114 0.972061898063839 1.0192558099197533 1.0 16.5450673207446 -1.5228787670643007 0.2602058863817532 0.9914380661608511 2.0546887203822277 0.3234239667948233 0.06054787063166425 58.58934547442356 0.8086881045428078 0.07560703285757307 27.62998312418265 0.029999998495217173 1.5228787670643007 1.0632506542213767 RQS(ph)PSPSTR ddPTM_PC-9_AZD4547_30min_R2 1 RQSPSPSTR 9 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 RQS(0.996)PS(0.001)PS(0.001)T(0.001)R 72.152 0.015153 10456000.0 656.74 1078.9 1185.5 865.28 705.14 839.01 715.9 1125.6 953.67 830.58 True False 865.5696589593964 1427.633325960581 1169.7794954080612 665.8030644427365 607.2434826023872 786.546572066801 779.6137131179343 951.6643837148241 1004.0790492441076 801.501647008876 1.0799349722980804 1.7811982436821756 1.4594848304723531 0.8306945680366933 0.7576322330322828 0.981341180023914 0.9726913425909661 1.1873517506374944 1.252747331201664 1.0 9.646561674757288 -5.747659369761532 24.462757779822784 0.9935996768630807 1.4743055775794405 0.48256415842123446 0.20915914336736394 148.65662541722128 263897.4171874723 0.05862931044449761 0.10082467630640048 1.787889320490727e-06 5.747659369761532 0.48070590071635977 RQS(ph)SGSATNVASTPDNR ddPTM_PC-9_AZD4547_30min_R2 4 RQSSGSATNVASTPDNR 17 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 RQS(0.875)S(0.04)GS(0.084)AT(0.001)NVASTPDNR;RQS(0.474)S(0.474)GS(0.033)AT(0.019)NVASTPDNR;RQS(0.926)S(0.066)GS(0.005)AT(0.003)NVASTPDNR;RQS(0.943)S(0.052)GS(0.005)ATNVASTPDNR 156.0 3.9798e-05 221488000.0 34447.299999999996 28813.7 71962.5 143692.1 93248.6 72502.8 47054.6 98130.2 55390.7 75589.6 True False 45400.824851649035 38127.165042386114 71008.23023053784 110566.10636581462 80302.64147799993 67969.18845454147 51242.368243161254 82966.43239766544 58318.5393196447 72943.23111168346 0.6224131308652311 0.5226964100892318 0.9734725093520612 1.5157829545078245 1.1008923001374653 0.9318094005250983 0.7024965505668923 1.137410985683311 0.7995058407866951 1.0 16.154486486620748 -5.3026242853412615 5.966046733427113 1.0330192967450809 0.5718820559688071 0.4265936391356845 0.20757750987596282 0.17624423216227936 17.385469282432986 0.05838049398206681 0.1274239029865315 4.981678710963777e-06 5.3026242853412615 -0.4611372407762737 RQS(ph)SGSATNVASTPDNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RQSSGSATNVASTPDNR 17 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 RQS(0.745)S(0.236)GS(0.018)AT(0.002)NVASTPDNR;RQS(0.728)S(0.265)GS(0.006)AT(0.001)NVASTPDNR;RQS(0.994)S(0.006)GSATNVASTPDNR;RQS(0.733)S(0.238)GS(0.025)AT(0.003)NVASTPDNR 166.36 3.5202e-05 39981600.0 41745.600000000006 45942.45 47259.1 56440.3 75156.8 53111.659999999996 45353.1 57118.4 50875.18 38754.3 True False 48812.30556681669 50503.31281292555 48385.936175134804 53278.13297292144 60430.36455760306 50326.39105186617 41056.92603999057 55619.10252194732 51619.133261115414 45780.14781112998 1.066233026773879 1.1031705930981568 1.0569196144747115 1.1637824585609697 1.320012438730295 1.0993059974269221 0.8968281668590177 1.2149174954919066 1.1275440497500069 1.0 15.48243450050421 -6.994832760932527 24.999584172149333 1.0663514714194122 1.1436772604216234 0.12338197699026432 0.1027719155970049 351.3604614645063 1699903.221597722 0.03841262175003996 0.03376968406565821 1.0119690704974812e-07 6.994832760932527 0.07732578900221121 RQS(ph)SGSATNVASTPDNR ddPTM_PC-9_Lapatinib_30min_R1 8 RQSSGSATNVASTPDNR 17 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 RQS(0.698)S(0.271)GS(0.023)AT(0.009)NVASTPDNR;RQS(0.428)S(0.221)GS(0.161)AT(0.188)NVAS(0.001)TPDNR;RQS(0.46)S(0.46)GS(0.078)AT(0.001)NVASTPDNR;RQS(0.418)S(0.418)GS(0.141)AT(0.019)NVAS(0.002)T(0.002)PDNR;RQS(0.989)S(0.011)GSATNVASTPDNR;RQS(0.774)S(0.221)GS(0.004)ATNVASTPDNR;RQS(0.941)S(0.059)GSATNVASTPDNR;RQS(0.572)S(0.385)GS(0.043)ATNVASTPDNR 108.69 0.00023263 133020990.0 67942.41 60850.99999999999 69883.20000000001 50137.100000000006 59676.200000000004 58430.2 53963.899999999994 49738.0 70251.1 50863.43 True False 66973.53877428811 60710.1032481743 64137.67305295305 53824.34958646264 56166.163243923365 55931.27655344881 56757.8866946094 52049.00905749605 62338.68134112124 59655.106104239734 1.1226790655146996 1.0176849428796773 1.0751413791952795 0.9022588861448241 0.9415147656561053 0.9375773543293343 0.9514338403058439 0.8724988095159366 1.0449848372106203 1.0 15.86435800843375 -5.751865472247436 24.999971434651982 0.9439095930744273 1.066420151266076 0.5430747529697351 0.050907094857289364 141.99393980696573 370779.5994783012 0.012992456618205625 0.02213939916074282 1.7706573550280949e-06 5.751865472247436 0.12251055819164869 RQS(ph)SPSCGPVAETSSIGNGDGISK ddPTM_PC-9_AZD4547_30min_R2 3 RQSSPSCGPVAETSSIGNGDGISK 24 1 Q9Y4K4 Q9Y4K4 MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 1 RQS(0.333)S(0.333)PS(0.333)CGPVAETSSIGNGDGISK;RQS(0.61)S(0.207)PS(0.183)CGPVAETSSIGNGDGISK;RQS(0.676)S(0.257)PS(0.067)CGPVAETSSIGNGDGISK 119.43 5.4133e-09 64104000.0 143386.0 135713.0 182670.0 266159.0 259948.0 203580.0 152647.0 233615.0 170761.0 208803.0 True False 188979.76538592414 179579.57323763845 180247.6764455425 204800.15466555834 223858.707229097 190850.11041746722 166232.28728357796 197515.16968864456 179787.07784450895 201492.87052468653 0.9378980253436346 0.8912452970172794 0.8945610630102114 1.0164139015552245 1.1110006356362383 0.9471804631126371 0.8250033207165585 0.9802588507192137 0.8922751329927665 1.0 17.620369266834487 -5.734056450786365 24.756685848713495 0.9658266962094777 0.906235805890315 0.12494157248610016 0.07208529550102122 473.56354150006086 428140.9337592689 0.02141347649698657 0.03707688667712017 1.844775614607038e-06 5.734056450786365 -0.05959089031916265 RQS(ph)SPSCGPVAETSSIGNGDGISK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RQSSPSCGPVAETSSIGNGDGISK 24 1 Q9Y4K4 Q9Y4K4 MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 1 RQS(0.565)S(0.324)PS(0.11)CGPVAETSSIGNGDGISK;RQS(0.659)S(0.248)PS(0.094)CGPVAETSSIGNGDGISK;RQS(0.507)S(0.247)PS(0.247)CGPVAETSSIGNGDGISK;RQS(0.641)S(0.207)PS(0.152)CGPVAETSSIGNGDGISK 111.38 2.0277e-07 93333000.0 208555.0 203745.0 197830.0 215114.0 242343.0 201078.0 182234.0 226209.0 183939.0 155482.0 True False 243859.24235098957 223971.45709620445 202547.01747445305 203061.8599889976 194857.62882378176 190533.1157024114 164971.47626009307 220271.25343824725 186628.75989660012 183669.6558051648 1.3277056641826201 1.2194254740357953 1.102778880847434 1.105581970515608 1.0609135622842625 1.037368501983405 0.8981966865288483 1.1992795024993628 1.016111012341496 1.0 17.486753771896097 -4.58664083649614 0.7698316272027378 1.0367588640290397 1.5897426889021296 0.6465008482827255 0.07012595566600852 2.2290978611406715 0.8223803782238172 0.027323845600593887 1.1377976737912114 2.590354264289033e-05 4.58664083649614 0.5529838248730898 RQS(ph)SPSCGPVAETSSIGNGDGISK ddPTM_PC-9_Lapatinib_30min_R1 4 RQSSPSCGPVAETSSIGNGDGISK 24 1 Q9Y4K4 Q9Y4K4 MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 1 RQS(0.39)S(0.39)PS(0.22)CGPVAETSSIGNGDGISK;RQS(0.66)S(0.247)PS(0.093)CGPVAETSSIGNGDGISK;RQS(0.429)S(0.429)PS(0.142)CGPVAETSSIGNGDGISK;RQS(0.333)S(0.333)PS(0.333)CGPVAETSSIGNGDGISK 139.25 1.2214e-07 89922000.0 205614.0 186439.0 214315.0 196994.0 207517.0 196229.0 158936.0 151209.0 209358.0 184421.0 True False 202681.90665501065 186007.31195027832 196694.84797982397 211481.59591271938 195311.25805411965 187836.7431021406 167164.92840017925 158234.72215559406 185777.89740252387 216297.92412446367 0.9370497080609151 0.8599588401192639 0.9093700218160228 0.9777328967384225 0.9029733357114065 0.8684167629554054 0.7728457361615179 0.7315591344489351 0.8588981986513299 1.0 17.72266029382957 -6.934505122785225 3.3370992085482194 0.8184581097644227 0.9171416278642481 0.17536219963991395 0.07211173687546353 0.3184494190691501 7.19399175076722 0.02680363985296608 0.02279997166916713 1.1627728352623534e-07 6.934505122785225 0.09868351809982545 RQS(ph)SSYDDPWK ddPTM_PC-9_AZD4547_30min_R2 4 RQSSSYDDPWK 11 1 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;H0YCF0;H7C1V2;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 RQS(0.873)S(0.074)S(0.053)YDDPWK;RQS(0.916)S(0.078)S(0.007)YDDPWK;RQS(0.896)S(0.063)S(0.041)YDDPWK;RQS(0.89)S(0.045)S(0.045)Y(0.02)DDPWK 169.58 8.379399999999999e-05 80483000.0 159466.0 171166.0 188473.0 183235.0 185076.0 195687.0 195365.0 213486.0 187262.0 187244.0 True False 210172.87090114708 226492.06216643687 185973.72487392934 140993.0017025295 159381.39204430216 183450.66095521636 212752.10652784607 180496.6441202406 197160.28701705023 180688.6445526384 1.163176974521602 1.2534936145389866 1.0292496539247173 0.7803091447811225 0.8820775231277526 1.0152860541370285 1.1774514500044684 0.9989373962438362 1.091160363204857 1.0 17.463146316763478 -5.342752070655218 5.502825698060722 0.9903244775116171 1.2073402383074334 0.4037339519872909 0.10320875114316892 0.21889538933667566 11.10567973522728 0.030350957604985546 0.06526255756059048 4.542008361044534e-06 5.342752070655218 0.2170157607958163 RQS(ph)SSYDDPWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RQSSSYDDPWK 11 1 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;H0YCF0;H7C1V2;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 RQS(0.952)S(0.04)S(0.008)YDDPWK 129.37 0.00038639 11227000.0 40297.0 35501.0 40860.0 39212.0 47802.0 23429.0 38509.0 31849.0 26971.0 23718.0 True False 47118.48619797085 39025.30466206461 41834.25736241292 37015.078767019244 38435.541249528214 22200.34199560271 34861.148738983626 31012.997496804903 27365.399850881015 28017.88564841532 1.6817288352604813 1.39287115208395 1.4931268507329014 1.321123200783454 1.3718216189415462 0.7923632166318858 1.2442462352956087 1.106899995451976 0.9767118116719414 1.0 14.774060467379568 -6.3205654215983875 1.4941157582473947 1.0471402461079553 1.5103779115578584 0.676077002108304 0.145273128116563 0.24307805433151072 1.0873678656568362 0.05390219043872175 0.07044859412092198 4.780073542724598e-07 6.3205654215983875 0.4632376654499031 RQS(ph)SSYDDPWK ddPTM_PC-9_Lapatinib_30min_R1 2 RQSSSYDDPWK 11 1 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;H0YCF0;H7C1V2;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 RQS(0.922)S(0.051)S(0.027)YDDPWK;RQS(0.624)S(0.264)S(0.112)YDDPWK 142.1 0.00020227 54524000.0 115781.0 203781.0 197749.0 188435.0 198744.0 164676.0 148950.0 174266.0 192332.0 135244.0 True False 114129.941708365 203309.15761476752 181490.84055321483 202293.13850073225 187054.2686657376 157633.1913585054 156661.90218205246 182363.0345493108 170669.54481425224 158620.74519869732 0.7195145979512287 1.2817311970139276 1.1441809854434182 1.2753258613640255 1.1792547590885596 0.9937741192745322 0.9876507766106438 1.1496795978412064 1.0759597970647654 1.0 17.275221940548484 -6.756340965562825 24.995077368110937 1.0474077032030238 1.1389589009472916 0.05385564240472751 0.1537966674733818 365.9835852240451 1794238.1266563013 0.051024128676746786 0.04949528633435011 1.752504066754142e-07 6.756340965562825 0.09155119774426779 RQS(ph)STPSAPELGQQPDVNISEWK ddPTM_PC-9_AZD4547_30min_R2 2 RQSSTPSAPELGQQPDVNISEWK 23 1 Q93100-4;Q93100-2;I3L213;Q93100-3;Q93100 Q93100-4;Q93100-3 PHKB Phosphorylase b kinase regulatory subunit beta 1 RQS(0.484)S(0.484)T(0.024)PS(0.007)APELGQQPDVNISEWK;RQS(0.454)S(0.454)T(0.055)PS(0.037)APELGQQPDVNISEWK 156.52 2.1225e-07 30646000.0 51812.0 46698.0 68090.0 106115.0 93151.0 65612.0 61191.0 71148.0 55767.0 69202.0 True False 68287.13824345128 61792.215270838075 67187.0821107844 81651.82621040702 80218.59155330122 61509.27126785964 66636.88045732585 60153.71141839222 58714.729769413025 66779.25904344939 1.022580052872716 0.9253204685998906 1.0061070319314214 1.222712371775208 1.2012500992427548 0.921083464370863 0.9978679220440152 0.9007843495126786 0.8792360174468357 1.0 16.02711246545914 -6.804496167516753 24.999723622248805 0.9372228078507796 1.0715585920457598 0.3641430876693952 0.08961323425472142 182.3071873933821 105850.28250307133 0.0357800166668056 0.03155520394998195 1.5685697396492217e-07 6.804496167516753 0.13433578419498016 RQS(ph)STPSAPELGQQPDVNISEWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RQSSTPSAPELGQQPDVNISEWK 23 1 Q93100-4;Q93100-2;I3L213;Q93100-3;Q93100 Q93100-4;Q93100-3 PHKB Phosphorylase b kinase regulatory subunit beta 1 RQS(0.25)S(0.25)T(0.25)PS(0.25)APELGQQPDVNISEWK;RQS(0.25)S(0.25)T(0.25)PS(0.25)APELGQQPDVNISEWK 71.527 0.00038173 21052000.0 50081.0 41746.0 47756.0 59606.0 64194.0 61551.0 56882.0 59252.0 53669.0 45965.0 True False 58558.724155162374 45890.26699029741 48894.684155638584 56266.46906525935 51615.64652048481 58323.1572056572 51493.72516998277 57696.697782683405 54453.8075932273 54298.09064126022 1.0784674647595172 0.8451543405731868 0.9004862524297369 1.036251337768098 0.9505978186507894 1.0741290626771762 0.948352410956667 1.062591651037553 1.0028678163472797 1.0 15.72861384699314 -5.764011982943796 24.99952898155151 1.0108350541324482 0.9317478478887521 0.1788548062675096 0.06711685582743111 96.27063969077707 935534.5271919663 0.017812961892031957 0.027865408702112585 1.7218210662780474e-06 5.764011982943796 -0.07908720624369614 RQS(ph)STPSAPELGQQPDVNISEWK ddPTM_PC-9_Lapatinib_30min_R1 2 RQSSTPSAPELGQQPDVNISEWK 23 1 Q93100-4;Q93100-2;I3L213;Q93100-3;Q93100 Q93100-4;Q93100-3 PHKB Phosphorylase b kinase regulatory subunit beta 1 RQS(0.462)S(0.462)T(0.054)PS(0.022)APELGQQPDVNISEWK;RQS(0.454)S(0.454)T(0.053)PS(0.039)APELGQQPDVNISEWK 79.873 9.4046e-05 22366000.0 83111.0 59819.0 60895.0 55734.0 59243.0 58071.0 44038.0 44183.0 66403.0 39779.0 True False 81925.8218993091 59680.49278076842 55888.448161497676 59832.86428317374 55758.44321621939 55587.438700112754 46318.07216041112 46235.9034779715 58923.99488541063 46654.747147814276 1.7560018413506124 1.2791944320625128 1.197915572973285 1.2824603698656385 1.195129040986167 1.1914637223088447 0.9927836928075832 0.9910224854822217 1.2629796213175095 1.0 15.509736263159587 -1.5228787452803647 0.7275946843639669 1.1106390523783194 93.85226928531864 0.7744273489659287 0.10082582918748408 160.91420573452447 0.7626489180568023 0.039925178298850256 24384.695514026487 0.029999999999998125 1.5228787452803647 92.74163023294032 RQS(ph)TDLPTGWEEAYTFEGAR ddPTM_PC-9_AZD4547_30min_R2 2 RQSTDLPTGWEEAYTFEGAR 20 1 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;Q9HAU0-5;Q9HAU0-3;Q9HAU0-7 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 RQS(0.941)T(0.059)DLPTGWEEAYTFEGAR;RQS(0.56)T(0.438)DLPT(0.001)GWEEAYTFEGAR 181.65 2.4408000000000005e-10 8842500.0 17942.7 12434.7 26009.0 36142.0 24799.0 19920.1 17939.7 23744.0 21013.6 20598.5 True False 23648.10536865542 16453.97360118828 25664.1036660213 27810.020288333697 21356.086911899198 18674.492997971283 19536.298546196114 20074.910382840062 22124.335995885343 19877.35278469544 1.1897009438230262 0.8277748943439296 1.2911228141898938 1.399080681897743 1.0743929105259082 0.9394859164722228 0.9828420694549468 1.0099388283884931 1.1130423771982338 1.0 14.27883801478509 -6.5165575823202495 24.762259327041647 1.0079214956015001 1.1697130781828637 0.2370349011377103 0.14180997269377665 426.2077059479547 1669614.852993438 0.0492153301662176 0.050914054095105514 3.0439843668809313e-07 6.5165575823202495 0.1617915825813636 RQS(ph)TDLPTGWEEAYTFEGAR ddPTM_PC-9_Lapatinib_30min_R1 1 RQSTDLPTGWEEAYTFEGAR 20 1 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;Q9HAU0-5;Q9HAU0-3;Q9HAU0-7 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 RQS(0.655)T(0.345)DLPTGWEEAYTFEGAR 99.859 0.00015586 4269400.0 18177.0 16760.0 16480.0 13483.0 17808.0 16432.0 13775.0 13299.0 19385.0 16001.0 True False 17917.79264674644 16721.193249731325 15125.078014639652 14474.584797969484 16760.56845187508 15729.241664862875 14488.202098407344 13916.920090386417 17201.657166900375 18766.75153000769 0.9547626086537256 0.891000939773431 0.8059507789856403 0.7712887749819084 0.8930990760481503 0.8381440783564544 0.772014382736457 0.7415732055776152 0.9166028089302106 1.0 14.195891325022489 -4.975431311689935 3.207594305704742 0.830001962522157 0.9532472045224382 0.16492572865698052 0.0747166489244748 0.3886171823259408 7.738955775426047 0.01854392640661773 0.09531212002597766 1.0582022687507232e-05 4.975431311689935 0.1232452420002812 RQS(ph)VGDFVSGALNK ddPTM_PC-9_AZD4547_30min_R2 1 RQSVGDFVSGALNK 14 1 Q6P4F7-3;Q6P4F7;H3BR51;Q6P4F7-2 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 1 RQS(0.995)VGDFVS(0.005)GALNK 91.20700000000001 0.0083343 0.0 7384.6 10355.0 11880.0 16230.0 16794.0 11719.0 11064.0 11004.0 11292.0 13519.0 True False 9732.749190778015 13702.05124693837 11722.463437745895 12488.424251000379 14462.44298554115 10986.209077425592 12048.674566191958 9303.584646764322 11888.8720669251 13045.703924863341 0.7460501362620009 1.0503113765156145 0.8985688702780132 0.9572825140695657 1.1085981307591763 0.8421323326591346 0.9235741233731987 0.7131531345758164 0.9113246886023929 1.0 13.671287171271723 RQS(ph)VGDFVSGALNK ddPTM_PC-9_Lapatinib_30min_R1 1 RQSVGDFVSGALNK 14 1 Q6P4F7-3;Q6P4F7;H3BR51;Q6P4F7-2 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 1 RQS(0.787)VGDFVS(0.213)GALNK 61.648999999999994 0.023492 3184900.0 32280.0 32016.0 38804.0 33661.0 39473.0 39440.0 32849.0 37580.0 39471.0 42132.0 True False 31819.681280573 31941.86891905717 35613.68490777167 36136.54222980426 37151.27574690389 37753.24313913046 34549.76048860859 39326.103992534925 35025.360331943484 49414.46006263886 0.6439346142857308 0.6464073244667038 0.7207138328057613 0.7312948918999982 0.7518300452905914 0.7640120541896769 0.69918320355646 0.7958420256476402 0.7088079134638842 1.0 15.592645656339904 -14.52287874527954 0.1627324803804435 2.03992928059126 0.6491049739261063 0.8286414905123864 0.03973210159030837 53.33330173427118 0.49234252206691603 17.931541825157087 0.1654101042582006 3.000000000005511e-15 14.52287874527954 -1.3908243066651536 RQS(ph)VSGLHR ddPTM_PC-9_AZD4547_30min_R2 2 RQSVSGLHR 9 1 Q8N1G4;J3KRP5 Q8N1G4 LRRC47 Leucine-rich repeat-containing protein 47 1 RQS(1)VSGLHR;RQS(0.994)VS(0.006)GLHR 80.834 0.0083026 35550000.0 7856.4 12159.0 34170.0 46804.0 38418.0 43576.0 31014.0 45025.0 38864.0 42449.0 True False 10354.571776728379 16089.158967795629 33716.88347371863 36014.06091459161 33084.32384295104 40851.18583137619 33774.18591792093 38067.420821570675 40918.271697571465 40962.87343047002 0.25277942950716403 0.3927741786743845 0.8231083576436439 0.8791878571634268 0.8076660905907406 0.9972734432489604 0.8245072449629028 0.9293151977286442 0.9989111668893477 1.0 15.322029299440317 -5.218227071052096 2.1414681388555787 0.9132745729016087 0.23876867379771965 0.9294677658990368 0.06543490650456822 0.08253569646052794 0.6833705497193941 0.01802651039632593 0.07389390067121263 6.050244547509169e-06 5.218227071052096 -0.674505899103889 down RQS(ph)VSGLHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RQSVSGLHR 9 1 Q8N1G4;J3KRP5 Q8N1G4 LRRC47 Leucine-rich repeat-containing protein 47 1 RQS(0.997)VS(0.003)GLHR;RQS(0.989)VS(0.011)GLHR;RQS(0.999)VS(0.001)GLHR 79.23 0.0093737 23940300.0 8546.0 22432.399999999998 42306.0 37648.0 55611.0 38541.0 45609.0 43012.0 41496.0 33978.6 True False 9992.669008806086 24659.340421433146 43314.735486398444 35538.70461646285 44714.42375690377 36519.842112447135 41288.585339435034 41882.98057498107 42102.80049728072 40138.651205550406 0.24895378167127577 0.614353987510752 1.0791278278032632 0.8853985759129974 1.1139991607570665 0.9098422845707665 1.0286490477220025 1.043457598026848 1.0489341129494334 1.0 15.292704517631204 -4.973535681054815 2.360342020492025 1.0127355135407206 0.2021100460547088 0.9220464528884367 0.07134051730453128 0.08865884416437483 0.8074226074545248 0.017957853515918467 0.1260098968090943 1.0628312588912451e-05 4.973535681054815 -0.8106254674860117 down RQS(ph)VSGLHR ddPTM_PC-9_Lapatinib_30min_R1 2 RQSVSGLHR 9 1 Q8N1G4;J3KRP5 Q8N1G4 LRRC47 Leucine-rich repeat-containing protein 47 1 RQS(1)VSGLHR;RQS(1)VSGLHR 104.07 0.0012504 29761000.0 32433.0 24184.9 31683.0 30203.0 29984.0 35628.0 28221.0 25286.0 34731.0 30455.0 True False 31970.499472516218 24128.901349965843 29078.146039916748 32424.229374254403 28220.400070812102 34104.27349292447 29682.145293586484 26460.879871081357 30819.22904635631 35719.10617126332 0.8950531774010927 0.6755180612379933 0.8140782107059177 0.9077559001277666 0.790064564759908 0.9547907870203646 0.8309879074596305 0.7408046479161234 0.8628219558066922 1.0 15.124408358709031 -12.523617456032754 1.267790394821111 4.205775246916535 0.827338708172234 0.2989615936747416 0.07789120118962067 343023.9571548612 7193.052447058554 3157042.2390941516 0.022436072016109906 2.9949015042584085e-13 12.523617456032754 -3.3784365387443014 RQSS(ph)PSCGPVAETSSIGNGDGISK ddPTM_PC-9_AZD4547_30min_R2 1 RQSSPSCGPVAETSSIGNGDGISK 24 1 Q9Y4K4 Q9Y4K4 MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 1 RQS(0.328)S(0.397)PS(0.275)CGPVAETSSIGNGDGISK 73.126 0.00019214 29738000.0 51290.0 49981.0 73522.0 113700.0 108340.0 78419.0 52376.0 82733.0 61455.0 72771.0 True False 67599.15310172577 66136.38081827402 72547.05024157854 87488.22164748887 93298.86108452603 73515.4475332911 57037.3625342435 69948.51586520835 64703.38583713092 70223.30943976846 0.9626312636220389 0.9418009681671318 1.0330907332671808 1.245857285073253 1.3286024516481922 1.0468809875209077 0.8122283468164551 0.9960868609475632 0.9213947100090454 1.0 16.099662367790835 -7.011550350599707 24.679918549421892 0.9317375471067314 1.106609016247418 0.30754290170202625 0.12048128880768354 657.1837964731621 1404220.6016056843 0.05002506326640197 0.041097408144248906 9.737548850116464e-08 7.011550350599707 0.17487146914068663 RQSS(ph)SYDDPWK ddPTM_PC-9_Lapatinib_30min_R1 1 RQSSSYDDPWK 11 1 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;H0YCF0;H7C1V2;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 RQS(0.166)S(0.371)S(0.371)Y(0.093)DDPWK 78.264 0.027301 17443000.0 25957.0 58940.0 65439.0 57388.0 65840.0 54418.0 50910.0 60637.0 57571.0 41961.0 True False 25586.848420069182 58803.5280512628 60058.85802184493 61608.504960755985 61967.42064642039 52090.6689945538 53545.870695456884 63454.41638625173 51086.747730493735 49213.90294048204 0.5199109782252633 1.194856017056363 1.220363645908728 1.251851637031585 1.2591446104439656 1.058454336725759 1.088023251482692 1.2893595629469132 1.0380551973753567 1.0 15.586778314420208 -4.759983942423028 24.99999045658567 1.1677350921465584 0.5199101879420692 0.7888575814064208 0.09847707687338074 15.666332919619945 269006.94706969475 0.023945302982304125 0.146252838451515 1.7378650832762363e-05 4.759983942423028 -0.6478249042044891 RQSSGS(ph)ATNVASTPDNR ddPTM_PC-9_AZD4547_30min_R2 1 RQSSGSATNVASTPDNR 17 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 RQS(0.08)S(0.021)GS(0.641)AT(0.259)NVASTPDNR 76.817 0.0328 0.0 4182.6 4289.0 4858.9 8498.1 5577.1 5425.7 4420.6 7176.7 4141.5 7406.2 True False 5512.579796515469 5675.335374033672 4794.467811251139 6538.994339336187 4802.815932753458 5086.430121289189 4814.024836163063 6067.705919159721 4360.411234960179 7146.911192271832 0.7713233938706816 0.7940962496036864 0.6708447442911478 0.9149399178776695 0.6720128183412837 0.711696281715281 0.6735811746714596 0.8489969660908774 0.6101112939076705 1.0 12.803104146075878 -11.003529523922358 5.496931815029707 1.0003579010739507 0.7437934315891984 0.4364332032645265 0.08829045541128762 0.000364308858116714 3.44198388075304e-05 0.08042114867982142 0.019478186650445012 9.91905905850887e-12 11.003529523922358 -0.2565644694847523 RQSSGS(ph)ATNVASTPDNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RQSSGSATNVASTPDNR 17 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 RQS(0.242)S(0.242)GS(0.352)AT(0.164)NVASTPDNR 76.693 0.0331 0.0 10894.0 9931.2 14562.0 18140.0 17508.0 15595.0 17062.0 12029.0 15894.0 11769.0 True False 12738.139033692196 10917.103902985713 14909.213306692529 17123.67461067349 14077.43308222961 14777.170746571528 15445.763841817205 11713.25149577902 16126.419681506159 13902.626536647267 0.9162397479436359 0.7852547771608676 1.0724026332284697 1.2316862979477694 1.0125736345662133 1.062904963146278 1.110996098550316 0.8425207614476975 1.1599548933431378 1.0 13.76306984763705 -5.270946972436077 24.4334365537878 1.062135709825246 0.8507472616417446 0.40637998118293095 0.10194893128386125 415.26927360913913 1067197.515982451 0.02642805240997757 0.05623194678040622 5.358620825355777e-06 5.270946972436077 -0.21138844818350133 RQSSGS(ph)ATNVASTPDNR ddPTM_PC-9_Lapatinib_30min_R1 1 RQSSGSATNVASTPDNR 17 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 RQS(0.062)S(0.062)GS(0.799)AT(0.077)NVASTPDNR 81.89 0.0022039 61297000.0 16937.0 14701.0 13416.0 11363.0 15056.0 12221.0 11542.0 15383.0 14276.0 9990.1 True False 16695.4752741346 14666.960737726746 12312.988267257626 12198.672925856794 14170.435681234892 11698.336318542424 12139.588284560265 16097.750338402462 12668.086547055449 11716.875474028491 1.424908484445501 1.2517808839257005 1.0508764298596902 1.0411199600863088 1.209403967179214 0.9984177389674269 1.036077264068288 1.3738944630831464 1.0811829975606895 1.0 13.516300278737296 -4.939352781255366 2.9685218237146853 1.1088551956726809 1.4320601205364107 0.4674706823542001 0.1093058048897409 0.2748751452646439 4.327705131664491 0.028800951429516473 0.17868716370326113 1.1498659631653092e-05 4.939352781255366 0.32320492486372987 RQST(ph)DLPTGWEEAYTFEGAR ddPTM_PC-9_Lapatinib_30min_R1 1 RQSTDLPTGWEEAYTFEGAR 20 1 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;Q9HAU0-5;Q9HAU0-3;Q9HAU0-7 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 RQS(0.093)T(0.907)DLPTGWEEAYTFEGAR 101.17 0.00023976 3987300.0 7056.7 4133.7 3930.3 6416.9 5108.2 6547.5 1899.7 5652.6 6559.9 4621.3 True False 6956.07016395971 4124.128671623773 3607.16590539674 6888.820232150881 4807.745719107605 6267.478687967971 1998.0571706965115 5915.240431830835 5821.0549831906 5420.085547504817 1.2833875227600413 0.7608973392536859 0.6655182605110965 1.2709799821005054 0.887023955059324 1.1563431302026697 0.36863941596204775 1.0913555478020023 1.0739784330286766 1.0 12.404099907087538 -4.74578609656326 24.600375166898747 0.914502151620776 1.283388769282689 0.15806955489167507 0.25177208934971057 1393.5859048726522 2189982.8614911046 0.061770571423207604 1.477481439111844 1.79561780626275e-05 4.74578609656326 0.3688866176619131 RQT(ph)IEER ddPTM_PC-9_AZD4547_30min_R2 1 RQTIEER 7 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 RQT(1)IEER 69.27600000000001 0.039875 11364000.0 9845.1 9458.3 15230.0 14755.0 21741.0 22226.0 11775.0 15845.0 9880.4 16047.0 True False 12975.63700919869 12515.510507862593 15028.040248894773 11353.462712477556 18722.637426976897 20836.204706447756 12822.952188802443 13396.519331877573 10402.657772763623 15485.199414326671 0.83793799886063 0.8082240449731266 0.9704776701158306 0.733181563162403 1.209066601341601 1.34555611128717 0.8280779501579323 0.8651176503082884 0.6717806787259867 1.0 13.918602341329073 -5.262306685249726 24.545658330704782 0.9589562355299018 0.8230810178857165 0.06663309793923788 0.19330087017456363 175.2357785678869 4959601.208175932 0.05432812493571099 0.12486844522643013 5.466298136011368e-06 5.262306685249726 -0.1358752176441853 RQTIEER ddPTM_PC-9_AZD4547_30min_R2 2 RQTIEER 7 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 ; 72.23 0.024919 6586000.0 20158.7 18339.1 21410.0 26690.0 30221.0 23134.0 18054.0 20282.9 21588.8 23661.0 False True 26568.747272992023 24266.855434353198 21126.089410954508 20537.032856389415 26025.335802431764 21687.427322908414 19660.771024767684 17148.64385967432 22729.939893591283 22832.63559184789 1.163630329320285 1.062814467332776 0.9252584672484028 0.8994595816052837 1.1398305595401255 0.949843360643466 0.8610819782796918 0.7510584483640177 0.9955022407359195 1.0 14.478809780322123 -6.996900189331113 24.49581461212783 0.88463654049076 1.0275093467335492 0.28028570052281554 0.10160771051961409 94.46103675844603 746453.6694425521 0.036833199761450656 0.03230948524756514 1.007163111058276e-07 6.996900189331113 0.1428728062427892 RQTIEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RQTIEER 7 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 ;; 94.302 0.0085371 6604800.0 18455.0 27432.2 20419.3 19500.9 30050.5 21451.399999999998 19732.199999999997 24236.8 21550.399999999998 19118.4 False True 21579.066997135065 30155.487522906078 20906.173552626493 18408.327795770834 24162.320244319224 20326.45082096853 17863.023167243296 23600.609681012316 21865.53383064871 22584.41457882887 0.9554848952057301 1.3352344121053508 0.9256903020290994 0.8150898811885613 1.069867016476465 0.9000211517558216 0.7909447067974252 1.0449954148085845 0.9681691661446007 1.0 14.463039897036778 -5.306573092686875 24.79527062639476 0.9344731936957456 1.1453598003299525 0.31954452161295166 0.12008229660971799 371.95850358312754 204343.44754937498 0.030046365310070818 0.06254690818527676 4.9365882742495206e-06 5.306573092686875 0.210886606634207 RQTIEER ddPTM_PC-9_Lapatinib_30min_R1 1 RQTIEER 7 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 85.064 0.012361 3123100.0 9349.7 8772.4 12956.0 10539.0 12255.0 13197.0 12518.0 13310.0 13937.0 9683.2 False True 9216.371563475006 8752.08804677465 11890.80769160627 11314.07321707338 11534.184994257024 12632.595073709555 13166.120788955595 13928.431190543903 12367.268296883709 11356.928217947032 0.8115197513453185 0.7706386690851822 1.0470091439704234 0.9962265323817114 1.0156078098679782 1.1123249906384565 1.1593029854806645 1.2264259246204618 1.0889624429729217 1.0 13.471285052067367 -5.271892753536975 0.7132965757979849 1.1313471979115906 0.6712879047413701 0.7106308618046473 0.07268577768629177 0.8791117966362644 0.5282184666121363 0.03377224324346668 0.2934335946249281 5.346963832159379e-06 5.271892753536975 -0.46005929317022043 RQVEEAER ddPTM_PC-9_AZD4547_30min_R2 4 RQVEEAER 8 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ;;; 146.79 0.00075284 15648400.0 52635.7 40234.4 59842.8 63558.0 61768.0 68160.6 47295.6 57175.0 71547.0 65081.0 False True 69372.7577094271 53239.38297342511 59049.24537140913 48905.6850613113 53192.57939328958 63898.506906969465 51504.81677628235 48339.91750079519 75328.82835390464 62802.53399911471 1.104617175326158 0.847726669343877 0.9402366689892084 0.778721525185603 0.8469814194764722 1.0174510937388324 0.8201073029474955 0.7697128511005084 1.199455237824743 1.0 15.938535150675943 -8.264420684826902 24.99643601305559 1.0997276172720325 0.8875962933194166 0.36754950054217284 0.10962057482943689 278.970596804412 2338933.501440087 0.08908642227591186 0.02681210660820612 5.439754688538046e-09 8.264420684826902 -0.2121313239526159 RQVEEAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RQVEEAER 8 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ;; 123.21 0.002085 14774600.0 34321.9 41315.0 42661.0 45174.0 55601.0 54377.0 36352.0 44357.0 47328.0 37929.0 False True 40131.9197815752 45416.48015867716 43678.20003274347 42643.04723608403 44706.383185118175 51525.37439476237 32908.475394311245 43192.67575012638 48020.08246422071 44805.22745420118 0.895697267078871 1.0136424417240328 0.9748460729808877 0.9517426795717692 0.9977939121236681 1.1499857789457797 0.7344784808413146 0.9640097418158827 1.0717517841708464 1.0 15.451379441794215 -5.513281496810432 0.003698841631648509 1.9364959421506645 0.00010312132446723256 0.013576556821355501 0.10293689203410165 386181.5012405411 288.05559541456785 73847.08773817545 76969.47850837167 3.0670333838527365e-06 5.513281496810432 -1.9363928208261971 RQVEEAER ddPTM_PC-9_Lapatinib_30min_R1 3 RQVEEAER 8 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ;; 146.79 0.00075284 11099100.0 43223.7 53941.0 42603.0 38552.0 48521.0 41656.9 37943.2 50829.0 53472.0 38870.6 False True 42607.32211174419 53816.102928625194 39100.345792335735 41387.242685701945 45667.090175956306 39875.331493976766 39907.71323849655 53190.700900387375 47449.42027487732 45589.33141818117 0.9345897556802567 1.1804538749423985 0.8576643827845738 0.9078273665842044 1.0017056349666957 0.8746636604123208 0.8753739525686755 1.1667357086788677 1.0408009680956702 1.0 15.476408631332799 -7.757721879734028 24.999909946077018 1.0778262496947282 0.9507365733709765 0.24898117548715837 0.09640102857660836 131.82591314769724 886538.6095096396 0.04826508532443895 0.026484558643947085 1.7469405277709922e-08 7.757721879734028 -0.12708967632375168 RQVQDESQR ddPTM_PC-9_AZD4547_30min_R2 1 RQVQDESQR 9 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 131.52 0.00077905 879190.0 981.89 1018.2 2150.4 2485.8 2128.1 736.03 1217.5 2999.6 1952.2 2843.0 False True 1294.110595419255 1347.313238013776 2121.8842909536006 1912.7372152271557 1832.650048679893 690.0059277461858 1325.8551413899775 2536.080743950771 2055.3893065047096 2743.4674353418513 0.4717061987863551 0.49109868069051577 0.7734315573128726 0.6971969816688631 0.6680050308129626 0.25150869985092683 0.4832771566048381 0.9244070883730979 0.7491939871517361 1.0 11.421784735939292 -7.763949175929465 24.999748175922505 0.8776004769037524 0.5534582131351057 0.525629133134038 0.14916496947822894 61.11545013673859 608736.0616094464 0.08382569310156535 0.04321664541404338 1.7220700914555862e-08 7.763949175929465 -0.32414226376864674 RQVQDESQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RQVQDESQR 9 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 131.12 0.0007872 1680600.0 3375.1 6687.4 5617.9 5116.4 7784.7 7569.4 2981.29 5441.6 6893.2 8248.6 False True 3946.4377687364145 7351.28087651308 5751.852042004396 4829.744695592606 6259.343917936532 7172.4473388328615 2698.880628529551 5298.763765851787 6994.000009346819 9744.005884118333 0.40501184170759563 0.7544413420865095 0.5902964458774894 0.4956631546646091 0.6423789140089273 0.736088157594729 0.27697855077534717 0.5437972666342694 0.7177746085669218 1.0 13.250299289107664 -8.59745056066866 3.0730143893454835 0.9993102097966216 0.5621837750794615 0.5007497317155135 0.1362617431688412 0.28287694813595377 6.593660652916291 0.13151937978325043 0.03496704683885147 2.526675326102015e-09 8.59745056066866 -0.43712643471716006 RQVQDESQR ddPTM_PC-9_Lapatinib_30min_R1 2 RQVQDESQR 9 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 123.75 0.00093706 2065370.0 3927.8999999999996 4822.6 3402.6 2520.91 3678.8999999999996 2112.87 3837.9 3264.28 4544.3 3454.7999999999997 False True 3871.8874257113607 4811.433565999664 3122.8513624158304 2706.3061309092354 3462.5143349956884 2022.507475440533 4036.607683011075 3415.9503656400198 4032.4730803995535 4051.957576768363 0.955559714620552 1.187434338796069 0.7707018899507974 0.6679009045962541 0.8545287726721994 0.4991432997809377 0.9962117338430946 0.8430370508381307 0.9951913375202833 1.0 11.984403354135221 -10.711428760142208 21.297812996040363 0.9999999576663237 0.8567083857859732 0.04757161159560841 0.1813504293814647 0.0 0.0 0.1832407170099706 0.04444240183211905 1.943440459560781e-11 10.711428760142208 -0.14329157188035047 RQWTSLS(ph)LR ddPTM_PC-9_AZD4547_30min_R2 2 RQWTSLSLR 9 1 Q9UHB6;Q9UHB6-4;F8VRN8;F8VTU2;F8VVQ7 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 RQWTS(0.001)LS(0.999)LR;RQWTSLS(1)LR 123.67 0.0021791000000000002 65098000.0 186960.0 140867.0 249930.0 326410.0 255150.0 197941.0 212010.0 259240.0 191350.0 215999.0 True False 246409.3909904199 186399.5029456752 246615.76489863894 251161.21748422857 219726.82670958783 185563.71797889745 230878.47928220913 219180.41474256513 201464.37035123253 208436.94075497924 1.182177161581343 0.8942728782648495 1.1831672639474184 1.2049745912336738 1.0541645157221915 0.8902631045474343 1.107665841025801 1.0515430419803322 0.9665482981160087 1.0 17.669251459928155 -6.519998919882901 24.997859994922564 1.0084276320243597 1.108147188632435 0.22975203832401314 0.09680967667041582 205.28926339252723 1782001.4248634656 0.032171999537240675 0.03274276741608884 3.019959231217107e-07 6.519998919882901 0.0997195566080753 RQWTSLS(ph)LR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RQWTSLSLR 9 1 Q9UHB6;Q9UHB6-4;F8VRN8;F8VTU2;F8VVQ7 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 RQWT(0.001)S(0.003)LS(0.996)LR 110.64 0.0011368 0.0 38901.0 34193.0 42351.0 47951.0 56542.0 37318.0 38953.0 46022.0 32404.0 24774.0 True False 45486.17097022763 37587.45506633543 43360.808457061925 45264.46092923951 45463.000990143155 35360.978385415576 35263.089844702 44813.97126433967 32877.847197654846 29265.330089123894 1.5542681675451873 1.284368054345109 1.4816442638785217 1.546692307634743 1.5534764464194077 1.2082890668831736 1.2049442031684823 1.5312990192785914 1.1234401627293964 1.0 14.83690493073613 -6.767412574064239 24.9994197346279 1.2462600066343783 1.4763362475484192 0.4531066464188439 0.14628011400473 159.22322263430223 666387.7630327697 0.05042850762908458 0.04563526582407596 1.7083915943379562e-07 6.767412574064239 0.23007624091404089 RQWTSLS(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 2 RQWTSLSLR 9 1 Q9UHB6;Q9UHB6-4;F8VRN8;F8VTU2;F8VVQ7 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 RQWTSLS(0.999)LR;RQWT(0.002)S(0.002)LS(0.996)LR 119.03 0.0025886 41329000.0 264803.0 184423.0 219543.0 163756.0 205664.0 154010.0 147676.0 160271.0 184537.0 155842.0 True False 261026.86066107664 183995.97987441544 201493.02200048754 175799.16251400218 193567.24787098146 147423.35131484477 155321.94069578245 167717.77575805155 163752.4997992415 182779.08205358757 1.4281002931426705 1.0066577521188727 1.102385566973213 0.9618122628631048 1.059022978429397 0.806565771413727 0.8497796298716767 0.9175983043228091 0.8959039402070756 1.0 17.47974144666898 -1.5228787452906158 0.6584043447367928 0.9100830698483682 45.705489025590474 0.7489993826948514 0.08327309416253625 113.2301864428711 0.7076953874994315 0.0344639952511069 7406.879353022648 0.02999999999929 1.5228787452906158 44.795405955742105 RRAS(ph)QEANLLTLAQK ddPTM_PC-9_Lapatinib_30min_R1 2 RRASQEANLLTLAQK 15 2 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2;H7C1L3 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 RRAS(0.999)QEANLLT(0.001)LAQK;RRAS(1)QEANLLTLAQK 52.891000000000005 0.026611000000000003 8396100.0 79655.0 43754.0 47972.0 34506.0 49398.0 57288.0 43434.0 42571.0 60026.0 48093.0 True False 78519.10509306192 43652.69030123774 44027.92733727509 37043.686348641626 46492.50676020465 54837.92578485057 45682.799995805835 44549.0040730762 53265.23977819769 56405.81097010566 1.3920392906801042 0.7739041341746348 0.7805565876999679 0.6567352850980955 0.8242503025946222 0.9722034811965377 0.8098952786977412 0.7897945851126329 0.9443218502155313 1.0 15.783556177384586 -4.758112979025739 24.999998408829597 0.8277631041362574 1.3920400728656865 0.7321271701651153 0.10013367703116699 48.24212872012822 362511.7920149032 0.02522636401585085 0.17708653523595067 1.745368047144717e-05 4.758112979025739 0.5642769687294291 RRAS(ph)SASVPAVGASAEGTR ddPTM_PC-9_Lapatinib_30min_R1 1 RRASSASVPAVGASAEGTR 19 2 V9GYZ0;Q9BZ23-3;Q9BZ23-4;Q9BZ23;A0A2R8YFI4 V9GYZ0 PANK2 Pantothenate kinase 2, mitochondrial 1 RRAS(0.842)S(0.148)AS(0.01)VPAVGASAEGTR 70.837 0.041210000000000004 0.0 10831.0 7554.2 12753.0 10781.0 11998.0 10074.0 10903.0 7585.0 9025.3 9041.5 True False 10676.547953837859 7536.708714028668 11704.49756800362 11573.87070436171 11292.301228975575 9643.15850364098 11467.503991211284 7937.426790403872 8008.775673377657 10604.311227958544 1.0068120148802178 0.7107211917882925 1.1037489674147254 1.0914306884776164 1.0648783297875233 0.9093620789077315 1.0814001725050195 0.7485094146875507 0.755237704855579 1.0 13.372363297421325 -7.76621036057783 24.99789336331028 0.8139051573975938 0.991738524364305 0.2439496763590191 0.12814334261155466 163.1524611858714 854826.4979177364 0.06835305310629008 0.03450613266066918 1.7131273136711462e-08 7.76621036057783 0.17783336696671115 RRAS(ph)VCSSGGGEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RRASVCSSGGGEHR 14 2 K7ER94;Q2V2M9-2;Q2V2M9;Q2V2M9-3;Q2V2M9-4 K7ER94 FHOD3 FH1/FH2 domain-containing protein 3 1 RRAS(0.948)VCS(0.049)S(0.003)GGGEHR 61.409 0.016672 442880.0 0.0 0.0 0.0 0.0 0.0 655.62 502.84 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 621.2381330469524 455.20735495366074 0.0 0.0 0.0 0.0 RRAS(ph)VCSSGGGEHR ddPTM_PC-9_Lapatinib_30min_R1 2 RRASVCSSGGGEHR 14 2 K7ER94;Q2V2M9-2;Q2V2M9;Q2V2M9-3;Q2V2M9-4 K7ER94 FHOD3 FH1/FH2 domain-containing protein 3 1 RRAS(0.484)VCS(0.484)S(0.032)GGGEHR;RRAS(0.909)VCS(0.073)S(0.018)GGGEHR 53.3 0.027087 1029910.0 2028.7600000000002 0.0 805.03 0.0 0.0 1972.42 492.97 0.0 1199.92 528.26 True False 1999.8295103709809 0.0 738.8435409056656 0.0 0.0 1888.064194535592 518.4935744792647 0.0 1064.7723738822342 619.5690371377954 3.2277750993005294 0.0 1.1925120472754402 0.0 0.0 3.047383070105998 0.8368616625429411 0.0 1.71856937654782 1.0 9.275121237252879 -7.486287272942491 24.955416576228668 0.7992536382746331 1.1449900054770106 0.015663708596086234 1.1583006824216857 3256.6735869597283 2221059.8608245607 0.48530450829643973 0.32706952116666316 3.263718754223592e-08 7.486287272942491 0.34573636720237744 RRDEDMLYS(ph)PELAQR ddPTM_PC-9_AZD4547_30min_R2 1 RRDEDMLYSPELAQR 15 2 Q9Y2W2 Q9Y2W2 WBP11 WW domain-binding protein 11 1 RRDEDMLY(0.152)S(0.848)PELAQR 60.364 0.016366 3218500.0 12983.0 13427.0 18397.0 34935.0 28993.0 19865.0 15739.0 25195.0 18440.0 18923.0 True False 17111.323936824076 17767.015170704155 18153.04375961374 26881.27549036957 24967.822405608815 18622.83840968166 17139.740509516927 21301.691673503017 19414.700753993882 18260.511529712934 0.9370670645770829 0.9729746695098997 0.9941147448183845 1.4720987112890676 1.3673123211790619 1.0198420991317334 0.9386232407360372 1.1665440827789282 1.0632068396552248 1.0 14.156439559496093 -10.60521621031441 14.520315657642051 0.9999999652840421 1.1096135640574687 0.02989160324707607 0.17386140032606104 0.0 0.0 0.1853195836110691 0.04494660104258363 2.4818972034056563e-11 10.60521621031441 0.10961359877342658 RRDEDMLYS(ph)PELAQR ddPTM_PC-9_Lapatinib_30min_R1 2 RRDEDMLYSPELAQR 15 2 Q9Y2W2 Q9Y2W2 WBP11 WW domain-binding protein 11 1 RRDEDMLY(0.024)S(0.976)PELAQR;RRDEDMLY(0.03)S(0.97)PELAQR 82.12100000000001 0.0025963 18850400.0 51471.0 41326.0 57553.0 44585.0 53298.0 46912.0 41219.0 42723.0 59451.0 37926.0 True False 50737.01410137459 41230.312186061856 52821.21450100465 47863.92963119998 50163.11642789966 44905.68311721318 43353.118133884025 44708.06654797951 52755.0023332161 44481.4585667816 1.1406328779709707 0.9269100770191994 1.1874883648813421 1.076042269597346 1.127730925293018 1.0095371097104353 0.9746334659596749 1.0050944368395136 1.1859998307837216 1.0 15.440916474997612 -6.773587033769751 24.985723845980836 1.0315951507617553 1.0870474630217242 0.1015026307121174 0.08345810769442458 576.7124539009791 1186195.8873253788 0.028989450690718083 0.025762985135132494 1.6842748597870744e-07 6.773587033769751 0.05545231225996883 RRDS(ph)GDNSAPSGQER ddPTM_PC-9_AZD4547_30min_R2 1 RRDSGDNSAPSGQER 15 2 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 RRDS(1)GDNSAPSGQER 93.115 0.0094981 20465000.0 2546.4 5394.0 7175.6 6382.5 2194.6 5243.5 5724.3 8552.0 6339.6 6727.7 True False 3356.102231589678 7137.505014580936 7080.446855546247 4911.113233642016 1889.9176715534481 4915.623116091907 6233.751610561517 7230.484905409712 6674.698313450088 6492.165270752504 0.5169465180914401 1.0994028520400916 1.0906140802428395 0.7564676850983449 0.291107449169172 0.7571623504775841 0.960196074897361 1.1137247133838954 1.0281158958660377 1.0 12.664484011636711 -7.395127254382733 3.808235626171481 1.0504668439141132 0.7631342605366374 0.2640806809466074 0.2262167026028607 0.3903492821636592 9.955154646134172 0.11296306924145821 0.07255618977703668 4.025990498647582e-08 7.395127254382733 -0.2873325833774758 RRDS(ph)GDNSAPSGQER ddPTM_PC-9_Lapatinib_30min_R1 1 RRDSGDNSAPSGQER 15 2 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 RRDS(0.996)GDNSAPS(0.004)GQER 79.804 0.029512 15597000.0 1165.9 3426.7 1572.1 2771.6 4379.9 5172.6 3928.4 5264.2 4198.2 3235.6 True False 1149.2740522001252 3418.765686685821 1442.8480064814937 2975.4327097865616 4122.282893214711 4951.379955919529 4131.793330191175 5508.793949906926 3725.3545069941265 3794.8691488340064 0.30284945465201235 0.9008915861397369 0.38021021276183303 0.7840672742829036 1.086278006313157 1.304756438687976 1.088784136723315 1.4516426611440694 0.981681939715566 1.0 11.889834425485207 -6.176694761610749 2.6465186319806366 1.1882065145754988 0.5648244668491454 0.6661295427510763 0.19911202154000918 0.15876312068365359 2.175443059156176 0.05921413462610369 0.07917481938104018 6.657408993882237e-07 6.176694761610749 -0.6233820477263533 RRDS(ph)LDSSTEASGSDVVLGGR ddPTM_PC-9_Lapatinib_30min_R1 1 RRDSLDSSTEASGSDVVLGGR 21 2 Q9Y2I9 Q9Y2I9 TBC1D30 TBC1 domain family member 30 1 RRDS(0.999)LDSSTEASGSDVVLGGR 93.34 0.0011231 7177800.0 14893.0 15206.0 15997.0 13377.0 15949.0 17902.0 10382.0 12986.0 18030.0 15841.0 True False 14680.623088958291 15170.791441253854 14681.788410205732 14360.789204363839 15010.911176940455 17136.373191600258 10919.529160483862 13589.376967723743 15999.27153568294 18579.09574319429 0.7901688699965901 0.816551658431012 0.7902315921690547 0.7729541524982096 0.807946273835157 0.9223469983934758 0.5877320032910534 0.7314337121440191 0.8611437153255229 1.0 14.18139266606249 -8.5715539441562 4.553241241866583 0.9999065536851669 0.7790454680757524 0.43173520527471754 0.0787309831928299 0.25117480017836114 16.98007326048486 0.07822086275826735 0.020397688183561594 2.681921462745377e-09 8.5715539441562 -0.22086108560941453 RRDS(ph)SEHGAGGHR ddPTM_PC-9_Lapatinib_30min_R1 1 RRDSSEHGAGGHR 13 2 O14641;I3L2N2 O14641 DVL2 Segment polarity protein dishevelled homolog DVL-2 1 RRDS(0.5)S(0.5)EHGAGGHR 54.772 0.025581 496200.0 0.0 478.65 1221.7 606.8 0.0 442.2 0.0 881.91 803.71 0.0 True False 0.0 477.54171533316844 1121.2565418983781 651.4260962254604 0.0 423.28813681854683 0.0 922.8867581707418 713.1877163584992 0.0 0.0 RREDS(ph)YHVR ddPTM_PC-9_AZD4547_30min_R2 1 RREDSYHVR 9 2 B1AVT0;P49760-2;P49760-3;P49760 B1AVT0 CLK2 Dual specificity protein kinase CLK2 1 RREDS(0.993)Y(0.007)HVR 79.23 0.0065369 3671700.0 5680.1 5289.8 7803.6 10927.0 6788.0 6499.3 6720.1 6962.3 5365.3 8644.2 True False 7486.253646580477 6999.624402322992 7700.119165218342 8407.948970467103 5845.603369408912 6092.897743571302 7318.175881441297 5886.436512737844 5648.898804522963 8341.569189089712 0.8974634720253908 0.8391256181724289 0.9231019956400589 1.0079577091399317 0.700779821745604 0.730425847398168 0.8773140539328075 0.7056749610657143 0.6771985793645869 1.0 13.026103088999825 -6.2682515456456445 24.988609555938506 0.7693797335259633 0.9117981435099823 0.30247776705969187 0.09923496005329448 642.1135528223267 2355417.6662127515 0.029940710872305102 0.03469891370093902 5.391982256077476e-07 6.2682515456456445 0.142418409984019 RREDS(ph)YHVR ddPTM_PC-9_Lapatinib_30min_R1 1 RREDSYHVR 9 2 B1AVT0;P49760-2;P49760-3;P49760 B1AVT0 CLK2 Dual specificity protein kinase CLK2 1 RREDS(1)YHVR 81.625 0.0054217 4833200.0 7394.7 6802.9 6354.4 5263.6 6810.1 7333.4 6204.5 5523.9 8442.6 4230.2 True False 7289.2502219781045 6787.148303018931 5831.96576069334 5650.702702854864 6409.543307171742 7019.767576990348 6525.738651148344 5780.560559988391 7491.705483480689 4961.384433612812 1.4691968178467019 1.3679948397138462 1.175471451311541 1.1389366775475005 1.291886043691317 1.4148808000912458 1.3153059873645772 1.165110391532201 1.5100030210771898 1.0 12.276527033664252 -10.720543023832947 4.526421130704572 0.9999284689109333 1.3063513024074662 0.3746332626190979 0.1220519885238071 89582081.30471276 8.889342901842522 66788.56058022246 0.03019951833393357 1.903079697674975e-11 10.720543023832947 0.3064228334965329 RREEEGLQLR ddPTM_PC-9_AZD4547_30min_R2 2 RREEEGLQLR 10 2 C9J352;C9JWD9;F2Z3G4;C9J4U1;C9JYI4;P52294 C9J352 KPNA1 Importin subunit alpha-5;Importin subunit alpha-5, N-terminally processed 0 ; 103.7 0.011054999999999999 9649200.0 14896.1 12300.9 19051.0 26540.0 26966.0 17595.0 16566.4 23253.7 16186.8 18934.7 False True 19632.749941872058 16276.925367789885 18798.37129229773 20421.613038912525 23222.236367041958 16494.78186853001 18040.77750663073 19660.374981866924 17042.401201992856 18271.801916274148 1.0744835146437175 0.8908221226551561 1.0288186889523239 1.1176573133010819 1.2709330187275403 0.9027452215229306 0.9873562328060457 1.075995409317349 0.9327159565370342 1.0 14.157331295260063 -8.2618376122139 24.997351299851772 0.9663579792203586 1.0414922387026804 0.0809154549576544 0.10393757842050673 105.63039196089484 6629153.168776219 0.08649558415700283 0.027689254902459874 5.47220536804059e-09 8.2618376122139 0.07513425948232177 RREEEGLQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RREEEGLQLR 10 2 C9J352;C9JWD9;F2Z3G4;C9J4U1;C9JYI4;P52294 C9J352 KPNA1 Importin subunit alpha-5;Importin subunit alpha-5, N-terminally processed 0 ; 128.27 0.0011554 6017400.0 16921.5 9754.2 18365.9 19918.8 20317.8 15883.4 20205.9 15492.300000000001 17490.8 13316.1 False True 19785.97573514066 10722.532512737971 18803.81270906362 18802.814213620917 16336.672942547688 15050.446542872336 18291.85087395231 15085.643540448687 17746.56986065735 15730.20351981039 1.2578334228303205 0.6816524973268254 1.19539538604077 1.195331909720108 1.038554454935915 0.9567865109893856 1.1628489644724442 0.9590240534046522 1.128184377163816 1.0 13.941249716235772 -7.125563949686147 0.002823669550408997 0.4263478640192041 1.6787545706548885 0.002804406573645113 0.16071147592282448 747516.2817558445 1121.2801966455506 247360.5621794002 249945.50883064096 7.489210720673215e-08 7.125563949686147 1.2524067066356843 RREEEGLQLR ddPTM_PC-9_Lapatinib_30min_R1 2 RREEEGLQLR 10 2 C9J352;C9JWD9;F2Z3G4;C9J4U1;C9JYI4;P52294 C9J352 KPNA1 Importin subunit alpha-5;Importin subunit alpha-5, N-terminally processed 0 ; 94.69200000000001 0.025133000000000003 7141300.0 28117.0 26218.0 28788.0 25687.0 26904.0 23526.1 21487.8 21412.7 26607.0 21136.2 False True 27716.046423973694 26157.29383182911 26421.161764893597 27576.10766932005 25321.559615299142 22519.943545017668 22600.333143387106 22407.612212904547 23610.239475868875 24789.56400778381 1.1180530006607208 1.0551736135260723 1.0658179287299072 1.1124079334618904 1.0214604664829234 0.9084445187477483 0.9116873994351294 0.9039131227103735 0.9524265722646581 1.0 14.597445277463011 -6.578887698000543 3.734596590075073 0.9282270222520204 1.0831259452788136 0.8318677241210632 0.032245441510327245 0.08408063344011818 2.415950767440971 0.010685511320688445 0.010907808123168106 2.637013189487425e-07 6.578887698000543 0.1548989230267932 RREEGPPPPS(ph)PDGASSDAEPEPPSGR ddPTM_PC-9_AZD4547_30min_R2 2 RREEGPPPPSPDGASSDAEPEPPSGR 26 2 Q9NTJ3;C9JWF0;C9IYK2;C9JJ64;C9JR83;E9PD53;Q9NTJ3-2;F8WCB7 Q9NTJ3 SMC4 Structural maintenance of chromosomes protein 4;Structural maintenance of chromosomes protein 1 RREEGPPPPS(0.88)PDGAS(0.073)S(0.043)DAEPEPPS(0.004)GR;RREEGPPPPS(0.801)PDGAS(0.098)S(0.098)DAEPEPPS(0.002)GR 61.256 0.0054843 29691500.0 11978.599999999999 9160.7 11606.8 17799.2 15764.7 14064.2 11862.4 12635.6 10224.5 10076.6 True False 15787.545629641894 12121.717127747786 11452.8862482516 13695.869434898714 13576.043523529861 13184.763350689394 12918.13061948621 10683.058357202413 10764.94619626954 9723.821301078335 1.623594792706764 1.246600153625153 1.1778174334591607 1.408486335858506 1.396163411808517 1.3559240696070025 1.3285034987277726 1.0986481575939393 1.1070695216371107 1.0 13.24730766523389 -7.770899940585859 3.333416569707839 1.064605029663216 1.356914913741722 0.5928851492233898 0.11208735742492806 0.18350378803060485 4.216285083273174 0.06693503121205094 0.031447611746542335 1.6947282129121564e-08 7.770899940585859 0.2923098840785061 RREEGPPPPSPDGAS(ph)SDAEPEPPSGR ddPTM_PC-9_AZD4547_30min_R2 1 RREEGPPPPSPDGASSDAEPEPPSGR 26 2 Q9NTJ3;C9JWF0;C9IYK2;C9JJ64;C9JR83;E9PD53;Q9NTJ3-2;F8WCB7 Q9NTJ3 SMC4 Structural maintenance of chromosomes protein 4;Structural maintenance of chromosomes protein 1 RREEGPPPPS(0.022)PDGAS(0.489)S(0.489)DAEPEPPSGR 57.39 0.0012354 30653000.0 9019.5 6901.7 11482.0 18329.0 11677.0 13379.0 3838.6 13997.0 11394.0 9694.4 True False 11887.513382745492 9132.53955490049 11329.741177794476 14103.532230227112 10055.850109691799 12542.409015007846 4180.227963646462 11834.085269062183 11996.263578687978 9355.002006745708 1.27071200777655 0.9762199461117373 1.211089123190441 1.507592646164836 1.0749169377452537 1.3407168706071642 0.44684415467064376 1.2650008263524537 1.2823368258005405 1.0 13.191522247601345 RREEGPPPPSPDGAS(ph)SDAEPEPPSGR ddPTM_PC-9_Lapatinib_30min_R1 2 RREEGPPPPSPDGASSDAEPEPPSGR 26 2 Q9NTJ3;C9JWF0;C9IYK2;C9JJ64;C9JR83;E9PD53;Q9NTJ3-2;F8WCB7 Q9NTJ3 SMC4 Structural maintenance of chromosomes protein 4;Structural maintenance of chromosomes protein 1 RREEGPPPPS(0.234)PDGAS(0.377)S(0.377)DAEPEPPS(0.011)GR;RREEGPPPPS(0.102)PDGAS(0.449)S(0.449)DAEPEPPSGR 71.143 0.0045693 26201000.0 33030.7 20785.5 26930.1 19246.7 23392.5 21246.4 21529.1 21150.9 23655.7 19102.8 True False 32559.676160911476 20737.372451807314 24716.011131192183 20662.16652310903 22016.599141424515 20337.740999777438 22643.77145530465 22133.648029156637 20991.34596043567 22404.69352711899 1.453252467903689 0.9255816164906017 1.1031622057795853 0.9222249122979175 0.9826779873054402 0.907744664088367 1.010670885897023 0.9879022894183187 0.9369173443514153 1.0 14.45151337160873 -4.757721875684253 24.999367690400344 0.9764071285756057 1.453253146012793 0.8735805352689181 0.054554473229458625 33.420340772879314 224711.37937202488 0.012925095566343112 0.0936845951582556 1.746940544061127e-05 4.757721875684253 0.47684601743718735 RREEGPPPPSPDGASS(ph)DAEPEPPSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RREEGPPPPSPDGASSDAEPEPPSGR 26 2 Q9NTJ3;C9JWF0;C9IYK2;C9JJ64;C9JR83;E9PD53;Q9NTJ3-2;F8WCB7 Q9NTJ3 SMC4 Structural maintenance of chromosomes protein 4;Structural maintenance of chromosomes protein 1 RREEGPPPPS(0.041)PDGAS(0.305)S(0.654)DAEPEPPSGR 60.464 0.00074903 14987000.0 13829.0 7981.3 12706.0 15738.0 15103.0 16340.0 13921.0 11432.0 9934.2 12633.0 True False 16169.976564799825 8773.630717425875 13008.959227773343 14856.250883284429 12143.675567792658 15483.101635073985 12602.302100687908 11131.922113205235 10079.468881340043 14923.26289722702 1.083541627334359 0.5879163811458522 0.8717235176625224 0.995509560181035 0.8137413145786734 1.0375144994564822 0.8444736373993396 0.7459442475729436 0.6754199098920229 1.0 13.865275387729048 -10.841703816231824 5.162836426220742 1.000037975122388 0.8489463895221514 0.08259559898962388 0.1492345023033182 7.778881714209111e-05 1.0263271797252085e-05 0.14239643069585242 0.03452571374743335 1.4397801567690567e-11 10.841703816231824 -0.1510915856002366 RREEGPPPPSPDGASS(ph)DAEPEPPSGR ddPTM_PC-9_Lapatinib_30min_R1 1 RREEGPPPPSPDGASSDAEPEPPSGR 26 2 Q9NTJ3;C9JWF0;C9IYK2;C9JJ64;C9JR83;E9PD53;Q9NTJ3-2;F8WCB7 Q9NTJ3 SMC4 Structural maintenance of chromosomes protein 4;Structural maintenance of chromosomes protein 1 RREEGPPPPS(0.004)PDGAS(0.188)S(0.808)DAEPEPPSGR 52.898 0.0034185 18530000.0 10040.0 6573.5 7523.7 8167.5 9050.1 8628.3 6494.6 7601.0 6485.6 6568.6 True False 9896.82775888949 6558.279464624637 6905.130428321868 8768.165195981284 8517.79091118119 8259.287722549685 6830.858609678144 7954.170208814735 5755.123431604287 7703.973757890669 1.284639339373765 0.8512852809120003 0.8963076258209475 1.13813539240066 1.1056360235465472 1.0720814974337425 0.8866669103956577 1.0324762854582425 0.7470331042742321 1.0 12.911387073587816 -7.259377716644133 24.998722333743334 0.9192504294664321 1.0470736296521739 0.20812809666289733 0.13413023841904956 342.457814234831 4152512.275515419 0.053158700143670155 0.03906994684591069 5.5032885359998684e-08 7.259377716644133 0.12782320018574178 RREY(ph)PDGT(ph)VK ddPTM_PC-9_AZD4547_30min_R2 1 RREYPDGTVK 10 2 Q9HC77 Q9HC77 CENPJ Centromere protein J 2 RREY(1)PDGT(1)VK 101.39 0.014925 21350000.0 96627.0 105130.0 109450.0 133030.0 113140.0 128690.0 109080.0 129080.0 102010.0 108200.0 True False 127352.37603354361 139111.2165707997 107998.62148664033 102361.98879301168 97432.4639385572 120642.99395630191 118787.90868404026 109133.65196331702 107402.04034245755 104411.95093351704 1.2197107217605156 1.3323304020952254 1.0343511496630022 0.9803665947989934 0.9331543282875353 1.1554519657727664 1.1376849835865717 1.0452218446986634 1.0286374249519044 1.0 16.671927325863308 -5.26868093937915 24.998581526694927 1.0427315854399426 1.276020566147587 0.6602763051271536 0.067868453000185 316.7403633389035 1093421.5506611944 0.01923008702435468 0.04141666176253174 5.38665375367398e-06 5.26868093937915 0.23328898070764437 RREY(ph)PDGT(ph)VK ddPTM_PC-9_Lapatinib_30min_R1 1 RREYPDGTVK 10 2 Q9HC77 Q9HC77 CENPJ Centromere protein J 2 RREY(1)PDGT(1)VK 89.266 0.039008 27865000.0 23496.0 44240.0 32579.0 30657.0 42895.0 34593.0 39194.0 34613.0 32798.0 29552.0 True False 23160.94273136131 44137.5649980975 29900.480378576794 32911.618048754004 40372.00043481474 33113.538030221614 41223.27354228517 36221.24634096891 29103.9438617487 34660.02382443521 0.6682321641981365 1.2734430080506942 0.862679164043074 0.9495555518213873 1.1648001351445294 0.9553812830006387 1.1893607964926698 1.0450438962316304 0.8396977454248173 1.0 15.080985025720432 -4.7332717027570625 24.78917062223413 1.0314595283329977 0.6682299419952574 0.396739597106583 0.13423798487497265 2976.2385572303924 2619104.6107080276 0.03204849432039652 3.1844923471105524 1.8481120437404632e-05 4.7332717027570625 -0.3632295863377403 RRFS(ph)DSEGEETVPEPR ddPTM_PC-9_Lapatinib_30min_R1 1 RRFSDSEGEETVPEPR 16 2 A0A1B0GV41;A0A1B0GWH8;H3BR84;A0A1B0GWD3;A0A1B0GV71;A0A1B0GW34;A0A0D9SFH9;H3BPL0;Q9UBD8;H3BQ48;O95090;H3BR00;Q9UP10;Q9UBH5;A0A0D9SF04;Q13286-5;Q13286-4;Q13286-6;Q13286-2;Q13286-7;Q13286-3;Q13286 A0A1B0GV41 CLN3 Battenin 1 RRFS(0.798)DS(0.197)EGEET(0.005)VPEPR 77.068 0.030739 4041600.0 7532.5 10022.0 6650.5 5065.6 4571.7 7752.8 5049.9 5010.8 8432.4 1792.3 True False 7425.085168708679 9998.794674749839 6103.721561672394 5438.141122346228 4302.801594308024 7421.230816659504 5311.359112649533 5243.620060824745 7482.654314891449 2102.0966669103686 3.5322282203234554 4.7565817653124025 2.9036350505438726 2.5870081085943255 2.0469094794923106 3.530394645250602 2.526695939466995 2.4944714214935426 3.5596147563895557 1.0 11.03761329918841 -1.522878745280387 0.0728414927877524 1.179156803375589e-14 10.020179859950968 0.443511319299975 0.7239581150685628 242.0852227234677 1.3025910393225075 30.047707108220067 247.18249457186974 0.029999999999996592 1.522878745280387 10.020179859950956 RRGNDPLTS(ph)SPGR ddPTM_PC-9_AZD4547_30min_R2 1 RRGNDPLTSSPGR 13 2 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 RRGNDPLT(0.033)S(0.484)S(0.484)PGR 73.758 0.0065677999999999995 22608000.0 15604.0 10419.0 20081.0 37447.0 28562.0 18736.0 20750.0 21625.0 10387.0 17386.0 True False 20565.747416637365 13786.737995350166 19814.71281930768 28814.172700382707 24596.659316007273 17564.43495815734 22596.70980192364 18283.35314306422 10936.035614519225 16777.321431886547 1.2258063660597593 0.8217484567678035 1.1810414969846346 1.7174477354662365 1.4660659280962154 1.0469153273045617 1.3468603968555382 1.089765921055512 0.6518344217769159 1.0 14.034224781537093 -8.03652224882428 5.202627871779241 0.8314367291506148 1.254387428734907 0.3423071693202496 0.23779995561818063 0.24422534063415322 16.84430416274756 0.17399500907114046 0.06693454131786229 9.193433758100545e-09 8.03652224882428 0.4229506995842922 RRGNDPLTSS(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 1 RRGNDPLTSSPGR 13 2 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 RRGNDPLT(0.015)S(0.243)S(0.742)PGR 85.976 0.0025013 25078000.0 47504.0 19591.0 31012.0 20483.0 19045.0 24275.0 7522.7 11415.0 18085.0 12948.0 True False 46826.584248833344 19545.638243167454 28462.313069781856 21989.388149284932 17924.810543910644 23236.814837788846 7912.188597146206 11945.382572506276 16048.076856507258 15186.04454787448 3.0835273860293952 1.2870789481453988 1.8742413786587762 1.4479997131552391 1.1803475544538353 1.5301426757003156 0.5210170806626298 0.7866026294633921 1.056764768858355 1.0 13.890458524947165 -1.522878745280338 0.46197779296935054 0.9303132840327879 45.81691589545218 0.7153343013352457 0.3603154664439134 51.357870161920346 0.6017927349620683 0.2182886869374354 2190.750412902218 0.029999999999999964 1.522878745280338 44.8866026114194 RRGS(ph)DIDNPTLTVMDISPPSR ddPTM_PC-9_AZD4547_30min_R2 1 RRGSDIDNPTLTVMDISPPSR 21 2 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 RRGS(0.999)DIDNPT(0.001)LTVMDISPPSR 58.93 0.031692000000000005 6633400.0 12697.0 13581.0 20977.0 22811.0 20942.0 19727.0 14666.0 23010.0 14930.0 28420.0 True False 16734.381885993615 17970.79265907003 20698.83127387169 17552.276376436836 18034.564785232975 18493.46757149711 15971.245588193347 19454.333217198022 15719.169319800898 27425.02445037474 0.6101865803720351 0.6552698865077756 0.7547424911626234 0.6400095069449244 0.6575952126447985 0.6743282072532267 0.5823603044399515 0.7093642980118544 0.573168835209046 1.0 14.743205286391907 -10.724175260438987 4.362957903578842 1.0001126011771913 0.6542572316008032 0.7998464883646417 0.05238206176275834 72483875.11972426 17.150499528102948 82467.21589610766 0.012213584989701336 1.887229599984345e-11 10.724175260438987 -0.34585536957638807 RRGS(ph)DIDNPTLTVMDISPPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RRGSDIDNPTLTVMDISPPSR 21 2 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 RRGS(0.999)DIDNPT(0.001)LTVMDISPPSR 50.956 0.035295 11084000.0 8726.3 10702.0 13240.0 16478.0 16679.0 13708.0 15734.0 17020.0 10678.0 10052.0 True False 10203.490237718754 11764.423832945986 13555.691812979607 15554.791082396796 13410.869681203314 12989.128348445167 14243.561615704592 16573.243034180643 10834.145549208686 11874.34802841178 0.8592884605794642 0.9907427173935969 1.141594618967279 1.309949063744705 1.1293984014208693 1.0938813918344021 1.1995236775630955 1.3957181476006773 0.9123991922155054 1.0 13.535560682719453 -5.068857897695649 2.475746838577506 1.1679371780753698 0.8613423798995512 0.32737230172104004 0.13199707694650487 0.34677774015249363 3.7634217408420723 0.03408940711790186 0.17120397166291756 8.533792963057324e-06 5.068857897695649 -0.3065947981758186 RRGS(ph)DIDNPTLTVMDISPPSR ddPTM_PC-9_Lapatinib_30min_R1 1 RRGSDIDNPTLTVMDISPPSR 21 2 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 RRGS(0.972)DIDNPT(0.027)LT(0.001)VMDISPPSR 55.208999999999996 0.045676999999999995 6326000.0 17848.0 20068.0 24445.0 14233.0 20621.0 18151.0 14738.0 14341.0 21511.0 16237.0 True False 17593.484247077664 20021.53377897424 22435.226460428796 15279.742299896134 19408.113322445864 17374.724042047605 15501.061526412159 15007.33521439444 19088.20465912787 19043.54381555747 0.9238555815806094 1.0513554605639004 1.1781014436031867 0.8023581350133724 1.019143994963299 0.9123682130976832 0.8139798808743093 0.7880537025957489 1.0023451960413963 1.0 14.217014354487043 -5.768678604719097 24.999997234281988 0.8978455571148919 1.0511292976612925 0.3131534224602728 0.09839010416067552 187.39264686333206 647145.2640444611 0.02777868748741154 0.04217203433077254 1.7034186399645285e-06 5.768678604719097 0.1532837405464006 RRGS(ph)DPASGEVEASQLR ddPTM_PC-9_Lapatinib_30min_R1 1 RRGSDPASGEVEASQLR 17 2 Q8WWA1-3;Q8WWA1-2;Q8WWA1 Q8WWA1-3 TMEM40 Transmembrane protein 40 1 RRGS(1)DPASGEVEASQLR 71.929 0.03572 19699000.0 25890.0 19076.0 16284.0 9963.0 9866.7 19873.0 1949.1 12550.0 18989.0 11810.0 True False 25520.803852355475 19031.830694025943 14945.192378057782 10695.712255593702 9286.360104678555 19023.078116225668 2050.014860980455 13133.118816027498 16850.258856965236 13851.342764164165 1.8424786886641948 1.3740061897294609 1.0789706552294407 0.7721787293622805 0.670430315875511 1.373374295916038 0.14800116464406615 0.9481477023299981 1.2165072472655711 1.0 13.757738219022512 -4.958669409042777 1.445255407056085 0.8558418670494466 2.0440472922230692 0.4854657519849317 0.31376037187201605 0.7132040184878217 1.7533279749832504 0.09088243821044595 1.119907666835058 1.0998427363430777e-05 4.958669409042777 1.1882054251736225 RRGS(ph)SGSVDETLFALPAASEPVIR ddPTM_PC-9_AZD4547_30min_R2 2 RRGSSGSVDETLFALPAASEPVIR 24 2 Q9NQC3-5;Q9NQC3 Q9NQC3-5 RTN4 Reticulon-4 1 RRGS(0.333)S(0.333)GS(0.333)VDET(0.002)LFALPAASEPVIR;RRGS(0.331)S(0.331)GS(0.331)VDET(0.006)LFALPAASEPVIR 60.133 0.0014436 6280800.0 10703.6 10827.0 15698.6 22899.2 21676.0 13735.599999999999 12999.7 19178.8 9636.1 17369.5 True False 14107.122151289379 14326.616016475313 15490.426306716976 17620.143229113248 18666.661554995237 12876.710760635455 14156.648116244176 16215.157144980332 10145.444573511952 16761.399091864325 0.841643473433952 0.8547386729446225 0.9241726315218963 1.0512334401527221 1.1136696556587387 0.7682360338812989 0.8445982366182996 0.9674107188850882 0.605286260288162 1.0 14.032854956907146 -6.796684918826263 24.999971242599845 0.8355376938948803 0.9548070243240708 0.1831404151288989 0.1266330651889564 334.065379284769 236953.21948026386 0.0453554990417165 0.04000131546199618 1.5970373795937062e-07 6.796684918826263 0.11926933042919052 RRGS(ph)SGSVDETLFALPAASEPVIR ddPTM_PC-9_Lapatinib_30min_R1 4 RRGSSGSVDETLFALPAASEPVIR 24 2 Q9NQC3-5;Q9NQC3 Q9NQC3-5 RTN4 Reticulon-4 1 RRGS(0.331)S(0.331)GS(0.331)VDET(0.008)LFALPAASEPVIR;RRGS(0.333)S(0.333)GS(0.333)VDETLFALPAASEPVIR;RRGS(0.333)S(0.333)GS(0.333)VDETLFALPAASEPVIR;RRGS(0.319)S(0.319)GS(0.319)VDET(0.042)LFALPAASEPVIR 83.115 0.00013593 9625600.0 66708.0 39845.9 35573.9 24971.1 29310.6 27186.3 22849.699999999997 17689.6 37672.100000000006 17865.8 True False 65756.73168725087 39753.63926667481 32649.15126122512 26807.557995147657 27586.608134856768 26023.605323360618 24032.74566155922 18511.523395059765 33429.07139320031 20953.879725317882 3.1381649865919186 1.89719707222724 1.5581434889013048 1.2793601159577608 1.316539394922878 1.2419468692433675 1.1469353635986201 0.8834413310434774 1.595364287254597 1.0 14.354929771076103 -1.9064820959808162 0.7652766672035531 1.1749164740638558 199.99990223318258 0.9138942860094887 0.17986631918763307 51.85561691692205 0.405619685580405 0.06291078566677774 17538.862170535787 0.012402747550461928 1.9064820959808162 198.82498575911873 up RRHES(ph)EEGDSHR ddPTM_PC-9_AZD4547_30min_R2 1 RRHESEEGDSHR 12 2 Q6UN15;Q6UN15-5;Q6UN15-3;H0Y8P7 Q6UN15;H0Y8P7 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 RRHES(1)EEGDSHR 63.211999999999996 0.015493 2651200.0 0.0 0.0 900.91 0.0 855.27 0.0 821.29 0.0 1656.8 660.16 True False 0.0 0.0 888.9633447558626 0.0 736.5305235348203 0.0 894.3832189504508 0.0 1744.3750655757615 637.047999337065 0.0 0.0 1.3954417024791692 0.0 1.156161740247643 0.0 1.4039494981244396 0.0 2.7382160643954943 1.0 9.315258268373524 -8.252377500072038 24.960143375903836 1.8691080880463975 0.5274070557242128 0.38486537773152163 0.6941637366919281 548.1007661114877 1509705.419617603 0.4451160112740422 0.1628682374594759 5.592712570149186e-09 8.252377500072038 -1.3417010323221847 RRHS(ph)EVETDSK ddPTM_PC-9_AZD4547_30min_R2 1 RRHSEVETDSK 11 2 Q9NX58 Q9NX58 LYAR Cell growth-regulating nucleolar protein 1 RRHS(0.998)EVET(0.002)DSK 70.808 0.010006000000000001 3533100.0 24091.0 15028.0 20894.0 17989.0 18519.0 19577.0 18755.0 16925.0 26629.0 29707.0 True False 31751.43687607092 19885.507111442766 20616.93190810292 13841.913977279472 15947.956511208564 18352.84709520955 20424.15866675072 14309.630147808639 28036.554575819053 28666.966972107068 1.1075966601895846 0.6936732138698645 0.7191877650734093 0.48285240607238433 0.5563182364819379 0.6402088896626857 0.7124631875643981 0.49916791552213724 0.9780091002685632 1.0 14.807101651906994 -8.287037941232477 21.474850103892155 0.9890060633119452 0.6679703414712557 0.36176348543688985 0.16576380444631808 162.65290506507503 136443.20832349802 0.16114521510932955 0.04174674062617325 5.163712556026805e-09 8.287037941232477 -0.3210357218406895 RRHS(ph)EVETDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RRHSEVETDSK 11 2 Q9NX58 Q9NX58 LYAR Cell growth-regulating nucleolar protein 1 RRHS(0.862)EVET(0.137)DS(0.001)K 54.471000000000004 0.028433999999999997 2945400.0 5181.8 5516.7 4301.9 4380.6 12292.0 15766.0 5231.0 8773.7 15306.0 17384.0 True False 6058.976394784855 6064.361517399843 4404.473611046601 4135.169184096821 9883.47083886031 14939.20320554323 4735.481810839628 8543.399671503568 15529.821293892883 20535.581588331712 0.29504771358545584 0.2953099473377275 0.21448010089712854 0.20136606145337602 0.48128516820171696 0.7274789438654936 0.23059886521696188 0.41602910707714824 0.7562396627089882 1.0 14.32583818602008 -9.612617235415941 0.2016849591124599 1.3566032547443252 0.14433730320320892 0.6633440199552522 0.15212252949351615 6.710499446333577 0.4798145779496102 2.094570573598246 0.5518878221677684 2.4399603252124375e-10 9.612617235415941 -1.2122659515411163 RRKEDEVEEWQHR ddPTM_PC-9_AZD4547_30min_R2 3 RRKEDEVEEWQHR 13 3 P15311;E7EQR4 P15311 EZR Ezrin 0 ;; 55.258 0.017172 40648600.0 49658.0 10623.8 63646.0 160792.0 132793.0 57497.0 52420.0 55546.0 48812.0 78698.0 False True 65448.21104943465 14057.735590267886 62802.01245444235 123723.8886116362 114356.98412403061 53901.70350070304 57085.27844900421 46962.64202009917 51392.10266832698 75942.8069738071 0.8618092174550241 0.18510950741018092 0.8269645929219201 1.6291719195250305 1.5058303568298794 0.7097670687797186 0.7516877598255367 0.6183948670253487 0.6767211368161867 1.0 16.212625703925866 -10.969168369748878 4.028922538232013 1.0007737903488951 0.8683322174970637 0.01035909718759398 0.3989687146389687 0.003122765672423508 0.0004291734253136134 0.4350219216966311 0.10489728305673499 1.0735731227321555e-11 10.969168369748878 -0.13244157285183145 RRKEDEVEEWQHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RRKEDEVEEWQHR 13 3 P15311;E7EQR4 P15311 EZR Ezrin 0 ; 70.72800000000001 0.006056000000000001 21119400.0 34135.0 11162.4 27072.0 45321.0 52892.0 66286.0 42928.0 79270.0 54345.0 31828.2 False True 39913.38130301846 12270.529302268378 27717.49915113173 42781.81130266447 42528.192288398954 62809.845470165994 38861.54906819416 77189.24649350764 55139.692814360926 37598.40070810744 1.061571251737094 0.3263577458395046 0.7371988868972008 1.1378625286431219 1.131117055179118 1.670545669157203 1.0335958002547259 2.0529928145816885 1.4665435703617844 1.0 15.198383676038711 -6.111517034914261 1.386252379642843 1.4827468982605019 0.6547546263735916 0.44864917955767547 0.3385107190611733 0.3441855434535248 1.335011460420307 0.12051155816202005 0.19424016830835 7.735403365709813e-07 6.111517034914261 -0.8279922718869103 RRLPGLSMS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 RRLPGLSMSPR 11 2 H0YFW5 H0YFW5 MSRB3 1 RRLPGLS(0.082)MS(0.918)PR 81.565 0.042057 35809000.0 69690.0 37283.0 87734.0 149400.0 127940.0 81901.0 53957.0 89442.0 70202.0 91266.0 True False 91849.9703579503 49334.000641197825 86570.58983562283 114958.13820699065 110177.73940515253 76779.71752284613 58759.06847144066 75620.79407269147 73912.73439977653 88070.80511920823 1.0429105335602051 0.5601629345209436 0.9829658048253926 1.3052922367564266 1.2510131962120872 0.8717953403391844 0.6671798718304814 0.8586363434549615 0.8392421790595868 1.0 16.426376234221806 -6.9813768036250075 24.915883083960402 0.8209132771611143 1.019913212069268 0.16597922914460383 0.20138959466660983 452.41286422427754 605278.8128804757 0.07861672976937989 0.0693223359335017 1.043814189649115e-07 6.9813768036250075 0.1989999349081537 RRLPGLSMS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RRLPGLSMSPR 11 2 H0YFW5 H0YFW5 MSRB3 1 RRLPGLS(0.008)MS(0.992)PR 99.73200000000001 0.012521 58992000.0 86411.0 70810.0 127110.0 131680.0 159470.0 147360.0 114380.0 184540.0 124120.0 83952.0 True False 101038.67560495483 77839.54883301312 130140.7844673595 124302.39651232019 128222.99826497362 139632.182187546 103545.09836051175 179696.02053629202 125935.0201880299 99171.83303633356 1.0188243225063442 0.7848957355108589 1.312275678313618 1.253404245001497 1.2929376652541715 1.4079822658555579 1.0440978571261859 1.8119663117495957 1.2698668193608071 1.0 16.597642801481605 -5.272675509002388 23.915859797856406 1.3209993510589777 0.9018600400907044 0.3489807107906966 0.21534579479443428 354.36553265708017 754261.5865443868 0.05421790208120876 0.11469081749874425 5.337335352331444e-06 5.272675509002388 -0.4191393109682733 RRLS(ph)ESSALK ddPTM_PC-9_Lapatinib_30min_R1 1 RRLSESSALK 10 2 Q96S55-2;Q96S55 Q96S55-2 WRNIP1 ATPase WRNIP1 1 RRLS(0.961)ES(0.037)S(0.002)ALK 111.72 0.0043723 20234000.0 30515.0 48174.0 50501.0 37660.0 74457.0 108420.0 98206.0 97215.0 87852.0 88473.0 True False 30079.85050423437 48062.45606280175 46349.0027194974 40429.64203007718 70077.58564809423 103783.1293393643 103290.62615435143 101731.96380080578 77957.18263742744 103765.44016713777 0.28988312925559756 0.4631836571539259 0.44667090164935286 0.38962531229045116 0.6753461030495161 1.000170472675662 0.9954241603753471 0.9804031442158717 0.7512827248827714 1.0 16.662966498079008 -6.506069843037861 2.853079529386596 0.947114310257715 0.40549836811434187 0.9048883996437133 0.0835547136595183 0.0776854702224195 1.2772989306931024 0.029172838727455238 0.03145853086956791 3.118388046042126e-07 6.506069843037861 -0.541615942143373 down RRLS(ph)PPSSSAASSYSFSDLNSTR ddPTM_PC-9_AZD4547_30min_R2 1 RRLSPPSSSAASSYSFSDLNSTR 23 2 P50402 P50402 EMD Emerin 1 RRLS(0.293)PPS(0.293)S(0.293)S(0.114)AAS(0.007)SYSFSDLNSTR 70.15 0.0029424 8018300.0 18423.0 17151.0 25858.0 37737.0 32041.0 21797.0 24564.0 32174.0 22623.0 21496.0 True False 24281.130777794788 22694.72534391503 25515.106024682947 29037.317680838027 27592.660217918536 20434.030144265344 26750.148413226605 27202.24758496868 23818.805594230143 20743.431582873174 1.1705455136864875 1.094068030800311 1.2300330310703995 1.3998319210025358 1.3301878287438436 0.98508436574866 1.2895719932526921 1.3113668042961721 1.1482577267445062 1.0 14.340366958274931 -8.536901546014805 20.118206291096893 0.9999999909035392 1.225639725636992 0.268461949028148 0.11443004849185157 214.45826407432313 307681.30708221364 0.1162308471955575 0.0300106756933643 2.9046810671908305e-09 8.536901546014805 0.22563973473345278 RRLT(ph)PEQK ddPTM_PC-9_AZD4547_30min_R2 1 RRLTPEQK 8 2 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 RRLT(1)PEQK 63.565 0.027154 4789000.0 10909.0 12075.0 16444.0 19609.0 19793.0 17041.0 13493.0 15420.0 15044.0 17584.0 True False 14377.835078703976 15978.007610505147 16225.941815681279 15088.44800602997 17045.083602049293 15975.423576107987 14693.850860595448 13037.19331634914 15839.195127065283 16968.38951215306 0.847330565367227 0.9416337124428583 0.9562452467312808 0.8892091966195943 1.004519821391494 0.9414814272542547 0.865954358843039 0.7683223742012566 0.9334530608058574 1.0 14.050562023210997 -7.262299938041126 24.897730823810257 0.8726259776562849 0.9333121774583174 0.04047034560753271 0.06776295278651372 143.8093729438219 4160574.988842524 0.02641942355881156 0.019006586720489358 5.466383061198844e-08 7.262299938041126 0.06068619980203249 RRLT(ph)PEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RRLTPEQK 8 2 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 RRLT(1)PEQK 87.29799999999999 0.0055850000000000006 3324000.0 13700.0 9171.1 10297.0 13438.0 16593.0 15718.0 13938.0 11914.0 13730.0 10692.0 True False 16019.139412665956 10081.546198311618 10542.519531589965 12685.112426583817 13341.720763847157 14893.720410042395 12617.691737618572 11601.270123926452 13930.775275391956 12630.374962174574 1.2683027590740614 0.7981984880499444 0.834695689016572 1.0043337956769431 1.0563202441576691 1.1791985950255701 0.998995815674991 0.9185214341355594 1.1029581716387533 1.0 13.624609849081876 -5.992107114567268 24.84705861365198 1.0420614953592893 0.9450682265805869 0.05333529252358482 0.13410356081496538 438.4691344193301 1380296.8315168375 0.03789417564447992 0.05609477553129848 1.0183401932394563e-06 5.992107114567268 -0.0969932687787024 RRMQSINDAFEGLRS(ph)HIPT(ph)LPYEK ddPTM_PC-9_AZD4547_30min_R2 1 RRMQSINDAFEGLRSHIPTLPYEK 24 3 Q7RTS3 Q7RTS3 PTF1A Pancreas transcription factor 1 subunit alpha 2 RRMQS(0.001)INDAFEGLRS(0.908)HIPT(0.897)LPY(0.194)EK 44.105 0.041917 10022000.0 9845.4 5410.5 12425.0 15699.0 13047.0 15065.0 12177.0 16171.0 10465.0 9346.1 True False 12976.032402958304 7159.33831690585 12260.236381649216 12079.838097132168 11235.649257613162 14122.983168479948 13260.729410025262 13672.14352261231 11018.15853527907 9018.895883731442 1.438760638801127 0.7938153859631623 1.3593943803880253 1.339392122146808 1.2457898840899546 1.5659326097727122 1.470327363901092 1.5159442684413884 1.2216748787569394 1.0 13.138735110541317 -5.4645923612467255 24.98927479869008 1.368229946279868 1.1063668107588522 0.1395241771291098 0.21269665418544792 384.7726361013059 164963.41041679797 0.052359071994795336 0.10899373362419784 3.4308966728466766e-06 5.4645923612467255 -0.2618631355210157 RRPENPKPQDGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RRPENPKPQDGK 12 3 H0Y449;P67809 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 49.448 0.036071 4932000.0 30650.0 34479.0 30648.0 37944.0 38961.0 28740.0 33257.0 29183.0 25865.0 30295.0 False True 35838.43963490598 37901.84725622727 31378.76455318724 35818.12069610776 31326.871733878663 27232.82380612156 30106.65620017082 28416.97717194439 26243.226693227454 35787.24368491196 1.0014305642101071 1.059088193266106 0.8768142310556498 1.0008627937783545 0.8753641942837356 0.7609645505502571 0.8412678122194669 0.794053250430267 0.7333123200066871 1.0 15.127157811953102 -6.4276390026018735 3.636994639671252 0.8138351664816509 0.9819876426442951 0.4658871421784502 0.0795167961775032 0.20188634734001085 4.940364913271215 0.024917275638996594 0.028029552468213228 3.735605424717879e-07 6.4276390026018735 0.16815247616264417 RRPESAPAES(ph)SPSK ddPTM_PC-9_AZD4547_30min_R2 2 RRPESAPAESSPSK 14 2 G5E9C8;Q07889 G5E9C8 SOS1 Son of sevenless homolog 1 1 RRPESAPAES(0.752)S(0.238)PS(0.01)K;RRPES(0.002)APAES(0.736)S(0.26)PS(0.003)K 82.12100000000001 0.027038 9761000.0 12691.900000000001 13449.8 17135.5 20075.9 15331.099999999999 15762.7 16747.3 16914.0 12711.099999999999 17111.6 True False 16727.66019208021 17797.18482482586 16908.2720738632 15447.711424563073 13202.641399049051 14777.055877185448 18237.777256180983 14300.329945053776 13382.982795775031 16512.52809236568 1.01302841687906 1.0777989127572853 1.0239662866451376 0.9355146188490114 0.7995530015269494 0.8948996661521139 1.1044812250531733 0.8660291062072634 0.8104744906967004 1.0 14.011273395445908 -5.762578731012525 3.9148241151241208 0.9110377828932832 1.0456600799976785 0.30634878884246763 0.08512802282871298 0.268241727479341 9.076548897648697 0.025363372769378643 0.04257829232464594 1.7275127802142398e-06 5.762578731012525 0.13462229710439533 RRPPDNSFY(ph)VRTCNK ddPTM_PC-9_AZD4547_30min_R2 1 RRPPDNSFYVRTCNK 15 3 H0YB73;H3BMM0;X6REH9;Q96B02;Q96B02-2;Q96B02-3 H0YB73 UBE2W Ubiquitin-conjugating enzyme E2 W 1 RRPPDNS(0.125)FY(0.87)VRT(0.004)CNK 57.885 0.026324 12071000.0 3925.5 1600.4 5033.7 5997.2 3444.7 3443.4 3727.5 1579.9 1825.5 5735.0 True False 5173.727344527682 2117.698002472253 4966.949849038848 4614.63819581636 2966.4628648501616 3228.083653657075 4059.2402788756785 1335.7627574902726 1921.9922031678875 5534.219395598145 0.9348612649225302 0.38265523122495754 0.8974978211000278 0.8338372344773305 0.5360219125410266 0.5832952080332515 0.7334801873059735 0.24136425790288024 0.34729237599373425 1.0 12.434164123164953 -6.277304801821 23.42446838018001 0.5441250412071326 0.7447648308865916 0.12091482268737919 0.23962591575622327 729.4755010284144 1077029.1941632023 0.07367922908826605 0.08388306331033715 5.28074502036139e-07 6.277304801821 0.20063978967945906 RRPS(ph)DENTIAPSEVQK ddPTM_PC-9_AZD4547_30min_R2 1 RRPSDENTIAPSEVQK 16 2 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 RRPS(0.676)DENT(0.324)IAPSEVQK 63.754 0.010279 5289500.0 31543.0 23296.0 34225.0 47494.0 37580.0 33785.0 31333.0 35562.0 30013.0 34565.0 True False 41573.017864841815 30825.976421890522 33771.15413778225 36544.99207498534 32362.66567801813 31672.418609166598 34121.57629993606 30066.71003346357 31599.425907246125 33354.889870767205 1.2463845039187829 0.9241816279809376 1.012479857335097 1.0956412153233939 0.9702525118028144 0.9495584824857972 1.0229857280938226 0.9014183572470598 0.947370116635894 1.0 15.025610657456308 -4.753716305767038 24.99948702577226 0.9819999925374331 1.2463849778029887 0.6938869684172986 0.05298419403044515 169.37105644903238 548207.5518487679 0.013846987255616491 0.14533165765272518 1.7631273982292885e-05 4.753716305767038 0.26438498526555565 RRPS(ph)DENTIAPSEVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RRPSDENTIAPSEVQK 16 2 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 RRPS(0.593)DENT(0.407)IAPSEVQK 57.973 0.01771 4600400.0 21503.0 17360.0 27268.0 23872.0 27529.0 27310.0 21857.0 25925.0 23668.0 17134.0 True False 25143.033196390952 19083.386071756897 27918.172534465888 22534.52923406822 22134.89006858003 25877.815523492685 19786.54672902348 25244.496219808072 24014.099724543088 20240.258567330628 1.2422288535865738 0.9428429981897062 1.3793387293741404 1.1133518457338647 1.093607079916829 1.2785318644723995 0.9775836935680519 1.2472417847741668 1.186452220689697 1.0 14.304940099987942 RRPS(ph)DENTIAPSEVQK ddPTM_PC-9_Lapatinib_30min_R1 1 RRPSDENTIAPSEVQK 16 2 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 RRPS(0.761)DENT(0.239)IAPSEVQK 53.168 0.024600999999999998 7286300.0 46077.0 35180.0 40936.0 33836.0 30643.0 25118.0 24735.0 28735.0 42528.0 32098.0 True False 45419.933530513066 35098.54287145274 37570.40009752965 36324.41231358712 28840.63898645596 24043.76169291784 26015.657270715492 30070.133002274888 37738.048800306366 37646.096532103424 1.2064978235334534 0.9323288761564373 0.9979892620604311 0.9648918655513404 0.7660990552330321 0.6386787451499537 0.6910585603086404 0.7987583248274363 1.0024425445576948 1.0 15.20021266129318 -6.102557565184672 3.1431963813870945 0.7912169824964027 1.0312686179374706 0.38957540488282216 0.12824169134474797 0.26498814172768104 4.991083928737326 0.0405750633366315 0.05573195691998357 7.896641734745689e-07 6.102557565184672 0.2400516354410679 RRPSDENT(ph)IAPSEVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RRPSDENTIAPSEVQK 16 2 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 RRPS(0.406)DENT(0.594)IAPSEVQK 64.52 0.014190000000000001 5036800.0 21380.0 28545.0 23781.0 32190.0 30924.0 31220.0 29017.0 34305.0 26433.0 23214.0 True False 24999.211725751706 31378.75895266706 24348.029229944717 30386.49866138807 24864.664189791452 29582.768240331076 26268.299695112517 33404.530099152 26819.53261867701 27422.51443807711 0.9116309075961114 1.1442699400714533 0.8878846352665837 1.108085793153795 0.9067244451977025 1.0787766492796291 0.957909959512614 1.2181424928987785 0.9780114321477815 1.0 14.74307324100317 RRPSDENT(ph)IAPSEVQK ddPTM_PC-9_Lapatinib_30min_R1 1 RRPSDENTIAPSEVQK 16 2 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 RRPS(0.016)DENT(0.983)IAPS(0.001)EVQK 53.49100000000001 0.035375 9299600.0 48636.0 32474.0 52848.0 47244.0 55622.0 43080.0 29730.0 34682.0 42912.0 38703.0 True False 47942.44172124996 32398.80844819662 48503.04143917941 50718.48136136393 52350.4233170595 41237.568824384885 31269.2739299928 36293.452332865796 38078.798676607126 45392.761981494165 1.0561693016343718 0.713743932598881 1.0685192819717217 1.117325299175251 1.1532768889102156 0.9084613278477464 0.6888603505277061 0.7995427188956249 0.8388737986935271 1.0 15.470174653147467 -6.9982252471834405 24.92742925885171 0.8127639191481558 1.014421561105093 0.3101913780124118 0.1327450282047793 68.22190361892427 958196.8338000178 0.04909280320700471 0.042997044078674496 1.0040948805850075e-07 6.9982252471834405 0.20165764195693725 RRS(ph)IQDLTVTGTEPGQVSSR ddPTM_PC-9_AZD4547_30min_R2 2 RRSIQDLTVTGTEPGQVSSR 20 2 O43318-3;O43318;Q9UG54;O43318-4;O43318-2 O43318-3 MAP3K7;DKFZp586F0420 Mitogen-activated protein kinase kinase kinase 7 1 RRS(0.766)IQDLT(0.229)VT(0.004)GT(0.001)EPGQVSSR;RRS(0.956)IQDLT(0.042)VT(0.002)GTEPGQVSSR 55.536 0.0071652 10300200.0 14430.5 6161.7 21453.1 63135.0 38589.0 21125.0 14975.0 25919.0 18072.0 27581.0 True False 19019.09882695369 8153.3490263892 21168.617876793473 48580.20117602646 33231.58344462588 19804.05041049709 16307.745989581035 21913.81410936793 19027.24902528077 26615.397585003022 0.7145900701355813 0.3063395540250493 0.7953523072193877 1.8252667847952775 1.248584896712228 0.7440824563017642 0.612718481378988 0.8233509959556534 0.7148962913107882 1.0 14.69997349717967 -10.830795987051172 2.985902407209416 1.001076202013947 0.8738600301870717 0.010272784455975237 0.3888523083653953 332965551.13922566 422307096.5825406 3205914.606061182 0.10658364989902845 1.4763999198566358e-11 10.830795987051172 -0.12721617182687528 RRS(ph)IQDLTVTGTEPGQVSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RRSIQDLTVTGTEPGQVSSR 20 2 O43318-3;O43318;Q9UG54;O43318-4;O43318-2 O43318-3 MAP3K7;DKFZp586F0420 Mitogen-activated protein kinase kinase kinase 7 1 RRS(0.977)IQDLT(0.023)VTGTEPGQVSSR 70.11399999999999 0.0013867 3934400.0 11426.0 5575.1 9826.6 14401.0 14224.0 15517.0 11987.0 19523.0 9715.7 7502.7 True False 13360.196126213234 6128.559083447686 10060.903411588024 13594.15865867194 11436.909307838352 14703.261203882665 10851.504581635378 19010.541936328354 9857.773732201422 8862.88011865948 1.5074327924266202 0.6914861762086699 1.1351731352437324 1.5338308175974824 1.2904280724456192 1.6589710124733752 1.2243767755347548 2.144962098303065 1.1122539851856217 1.0 13.113559883859915 -5.685969800208515 5.429501470282935 1.4669298997689764 1.058291367139549 0.12799426047346063 0.3568223656665246 0.3108603088458134 16.00415588106389 0.09169496417603488 0.15999838343572534 2.0607732094895824e-06 5.685969800208515 -0.4086385326294273 RRS(ph)IQDLTVTGTEPGQVSSR ddPTM_PC-9_Lapatinib_30min_R1 1 RRSIQDLTVTGTEPGQVSSR 20 2 O43318-3;O43318;Q9UG54;O43318-4;O43318-2 O43318-3 MAP3K7;DKFZp586F0420 Mitogen-activated protein kinase kinase kinase 7 1 RRS(0.822)IQDLT(0.173)VT(0.005)GTEPGQVSSR 51.566 0.013449000000000001 3587500.0 25531.0 13983.0 21541.0 15878.0 15548.0 21468.0 10253.0 8387.1 18473.0 10098.0 True False 25166.923258188028 13950.623222612963 19769.982130664623 17045.72108745528 14633.497208544115 20549.863684352254 10783.8501716857 8776.795284613885 16392.376210686136 11843.425845260783 2.1249698851501417 1.1779212708285236 1.6692790066799548 1.439255947575019 1.2355797553627437 1.7351283279723835 0.9105346976948332 0.74106896089749 1.384090754217509 1.0 13.531798836789099 -1.5228787452803478 0.20837394029338097 0.9270091955111441 5.4979088109268215 0.42313415785912833 0.30270578697582684 53.02440351386404 0.6570056788595237 0.5208865477153012 80.12394623730354 0.02999999999999929 1.5228787452803478 4.570899615415677 RRS(ph)PPADAIPK ddPTM_PC-9_AZD4547_30min_R2 2 RRSPPADAIPK 11 2 P18754-2;M0R1Q8;C9JRH2;C9J3R0;C9JMJ4;C9JQZ4;C9JW69;P18754 P18754-2 RCC1 Regulator of chromosome condensation 1 RRS(1)PPADAIPK;RRS(1)PPADAIPK 99.991 0.012182 806830000.0 690230.0 697410.0 741440.0 1086950.0 966130.0 824780.0 695890.0 878430.0 746590.0 808390.0 True False 909708.7823241202 922834.1439041327 731608.0211517104 836370.4707100955 831999.5261177123 773206.3762163224 757822.8618824395 742688.8278132677 786053.2232063067 780088.5121547643 1.1661609780809592 1.1829864554152654 0.9378525766657674 1.072148169955572 1.06654503066525 0.9911777499204135 0.9714575334396061 0.952057127160877 1.0076461977821807 1.0 19.573278302004 -3.2260136138104243 0.5050454472407128 0.9840886837257178 2.1266497792392403 0.5765960484005552 0.052752981141948 13.464113910513886 0.7600855667544871 0.02987529255494487 12.82593035713495 0.0005942735296568478 3.2260136138104243 1.1425610955135226 RRS(ph)PPADAIPK ddPTM_PC-9_Lapatinib_30min_R1 1 RRSPPADAIPK 11 2 P18754-2;M0R1Q8;C9JRH2;C9J3R0;C9JMJ4;C9JQZ4;C9JW69;P18754 P18754-2 RCC1 Regulator of chromosome condensation 1 RRS(1)PPADAIPK 87.083 0.029708 363360000.0 422760.0 280310.0 365410.0 292650.0 290930.0 335070.0 283320.0 295750.0 342380.0 260870.0 True False 416731.36487531173 279660.95941719465 335367.4003233914 314172.45725178195 273818.0693903872 320739.83718631946 297988.92330459313 309491.62468845636 303817.5589787646 305961.0319125748 1.3620406568454393 0.9140411040877418 1.0961114826518796 1.0268381410791996 0.8949442603155683 1.0483029004751414 0.9739440393498883 1.0115393543870985 0.9929942943373825 1.0 18.222988393216042 -4.7533104074308055 24.997511749673002 0.9977445882245765 1.3620413257021997 0.7936681918280653 0.05606893950934937 128.04699061924643 393728.17346578377 0.013419514632383979 0.14634232501027608 1.764776014641777e-05 4.7533104074308055 0.36429673747762326 RRS(ph)PPPGPDGHAK ddPTM_PC-9_AZD4547_30min_R2 4 RRSPPPGPDGHAK 13 2 P57081-3;P57081-2;P57081 P57081-3 WDR4 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 1 RRS(1)PPPGPDGHAK;RRS(1)PPPGPDGHAK;RRS(1)PPPGPDGHAK;RRS(1)PPPGPDGHAK 64.65 0.013288 50488000.0 136544.0 126425.0 165540.0 189926.0 160550.0 159920.0 132258.0 173461.0 150670.0 177117.0 True False 179962.1517083656 167289.40887437775 163344.83143808565 146141.49502744916 138260.40379472595 149920.17711937052 144028.7057823045 146656.58818723998 158634.1086010986 170916.18774021877 1.0529263148666532 0.9787803664837559 0.955701350455809 0.855047710574814 0.8089368574313895 0.8771561026579835 0.8426861591437935 0.8580614283893825 0.9281397549201827 1.0 17.382929517832117 -5.34992199808245 1.7682701891960686 0.8713122601409565 1.0368559550877363 0.5140914906895901 0.052575749838324456 0.2988293494005072 1.6839298113472887 0.01484324603677119 0.05587380111597788 4.467638264327655e-06 5.34992199808245 0.16554369494677978 RRS(ph)PPPGPDGHAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RRSPPPGPDGHAK 13 2 P57081-3;P57081-2;P57081 P57081-3 WDR4 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 1 RRS(1)PPPGPDGHAK;RRS(1)PPPGPDGHAK;RRS(1)PPPGPDGHAK;RRS(1)PPPGPDGHAK 65.809 0.012433 37204400.0 107965.0 127545.0 131273.0 144317.0 133814.0 122185.0 147492.0 139937.0 131857.0 116527.0 True False 126241.34209404941 140206.8246844605 134403.04617562474 136231.38637202667 107594.10729183674 115777.40350560063 133520.4900103915 136263.80202550752 133785.159176064 137652.42267277543 0.9171022176205921 1.0185568983246838 0.9763943384790615 0.9896766342854217 0.781636132533659 0.8410851131972035 0.9699828554982555 0.9899121234461024 0.97190559075081 1.0 17.070670475923073 -10.198714437062534 8.83660000541447 0.9999849948992741 0.9392941120051822 0.06191940107052163 0.07053965664482276 0.0 0.0 0.07542229335628868 0.018292593060841144 6.328278197561141e-11 10.198714437062534 -0.06069088289409186 RRS(ph)PPPGPDGHAK ddPTM_PC-9_Lapatinib_30min_R1 4 RRSPPPGPDGHAK 13 2 P57081-3;P57081-2;P57081 P57081-3 WDR4 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 1 RRS(1)PPPGPDGHAK;RRS(1)PPPGPDGHAK;RRS(1)PPPGPDGHAK;RRS(1)PPPGPDGHAK 82.069 0.0034934 47736900.0 120857.0 129976.0 138593.0 123249.0 151285.0 140037.0 140646.0 159145.0 153102.0 122753.0 True False 119133.55701754076 129675.04855770156 127198.41852445126 132313.14260661165 142386.71373775386 134047.94395219113 147927.96169383658 166539.4576873865 135858.04052446628 143970.6924919092 0.82748478148937 0.9007044858451937 0.8835021650784899 0.9190283127522453 0.9889979083469064 0.9310779967230087 1.0274866303233887 1.156759440444767 0.94365067065369 1.0 17.135415632633183 -6.350528677571275 0.7698805197316159 1.0411897643973163 0.8548189608222804 0.5583636531664514 0.05769597984324769 0.5063830872790578 0.657361741441298 0.03398803131255167 0.052999303040129675 4.461401638364535e-07 6.350528677571275 -0.18637080357503588 RRS(ph)QSIEQESQEK ddPTM_PC-9_AZD4547_30min_R2 1 RRSQSIEQESQEK 13 2 A0A0A0MRN0;Q5VTL8 A0A0A0MRN0 PRPF38B Pre-mRNA-splicing factor 38B 1 RRS(0.999)QS(0.001)IEQESQEK 103.04 0.0044923 7336000.0 25576.0 19432.0 19373.0 32471.0 30993.0 20707.0 20307.0 23259.0 19798.0 25335.0 True False 33708.635986152076 25713.01398652886 19116.10136190667 24985.31262194908 26690.156928121745 19412.188016575794 22114.28366012834 19664.855988648804 20844.481861581946 24448.029361373825 1.3787874469510153 1.051741782802078 0.7819076572326427 1.0219765467651198 1.0917099506715386 0.7940185169789469 0.9045425843224552 0.8043534183461797 0.8526037642328248 1.0 14.577430560671669 -4.833134630680644 3.093036506423869 0.9059398287214706 1.4245752827211977 0.6728494485568508 0.0997303835989153 0.19050629583257353 2.8853711064099166 0.02641453849656554 0.2290178636242296 1.4684709831307523e-05 4.833134630680644 0.5186354539997271 RRS(ph)QSIEQESQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RRSQSIEQESQEK 13 2 A0A0A0MRN0;Q5VTL8 A0A0A0MRN0 PRPF38B Pre-mRNA-splicing factor 38B 1 RRS(0.5)QS(0.5)IEQESQEK 47.545 0.038891 2611500.0 15391.0 13522.0 14580.0 16215.0 22433.0 19752.0 17612.0 22770.0 20886.0 16444.0 True False 17996.392313893575 14864.374796215248 14927.64249495792 15306.526119739297 18037.414686637934 18716.170348591262 15943.66386016203 22172.31162680923 21191.418237570022 19425.167029367632 0.9264472365507084 0.7652121999127615 0.7684691962951875 0.7879739770885041 0.9285590522525934 0.9635011282165818 0.8207735787320569 1.1414219292574612 1.0909259212820208 1.0 14.245639383402736 -7.277811868266902 0.9071261668967286 1.0785416802410213 0.8136736855524715 0.5524875118287895 0.08484074586476405 0.43209862363772505 0.6891087215474134 0.06703271567913296 0.03839045505599674 5.274583012454387e-08 7.277811868266902 -0.2648679946885497 RRS(ph)SDEDAAGEPK ddPTM_PC-9_AZD4547_30min_R2 1 RRSSDEDAAGEPK 13 2 E9PHH9;Q9BUI4 E9PHH9 POLR3C DNA-directed RNA polymerase III subunit RPC3 1 RRS(0.5)S(0.5)DEDAAGEPK 95.073 0.010143000000000001 15340000.0 34551.0 38466.0 46457.0 49130.0 52141.0 47250.0 40720.0 51332.0 34512.0 38827.0 True False 45537.49929455505 50899.38225637194 45840.94982553546 37803.837550933386 44902.12216917356 44295.45003057929 44344.00111490746 43399.818892012576 36336.233862355555 37467.67854801902 1.215380857829066 1.3584877480770174 1.223479852555721 1.0089719730696296 1.1984228516220046 1.182230972057949 1.1835267845077635 1.158326871956875 0.9698021139950426 1.0 15.193358972348234 -1.5228787477681192 0.09654460355386169 0.8857842788076818 2.020213069665845 0.4585767902479826 0.08472357695543765 134.3337743738756 0.9273886141941078 1.3020850518995974 20.168168716049873 0.029999999828150135 1.5228787477681192 1.1344287908581632 RRS(ph)SDEDAAGEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RRSSDEDAAGEPK 13 2 E9PHH9;Q9BUI4 E9PHH9 POLR3C DNA-directed RNA polymerase III subunit RPC3 1 RRS(0.871)S(0.129)DEDAAGEPK 91.65700000000001 0.014074000000000001 10530000.0 32161.0 39751.0 39495.0 44707.0 63194.0 61939.0 48159.0 53668.0 53349.0 52967.0 True False 37605.222091295625 43697.21657479308 40436.71058562161 42202.211732049625 50811.58934192471 58690.809802622214 43597.030879033795 52259.27186594636 54129.1281986078 62569.49781345867 0.601015245534011 0.6983788923009995 0.6462687411392918 0.6744853835629148 0.8120824222277065 0.938009922623957 0.6967777016368524 0.835219614863289 0.8651040856998 1.0 15.93317190447626 -3.525690143684982 0.11753235250691009 1.096978080236284 1.809671841611026e-14 0.7022434358834447 0.06885460139678523 36.118856941407195 0.48027132842556386 0.6705940305095944 6.297281989458178 0.0002980642271403081 3.525690143684982 -1.0969780802362659 RRS(ph)SDEDAAGEPK ddPTM_PC-9_Lapatinib_30min_R1 1 RRSSDEDAAGEPK 13 2 E9PHH9;Q9BUI4 E9PHH9 POLR3C DNA-directed RNA polymerase III subunit RPC3 1 RRS(0.762)S(0.238)DEDAAGEPK 128.82 0.00028186 15206000.0 77584.0 73118.0 55292.0 61402.0 80278.0 63001.0 79797.0 69520.0 72824.0 71543.0 True False 76477.63793283708 72948.69976335637 50746.10519329223 65917.70791106737 75556.20587262056 60306.59409250403 83928.49821028028 72750.15299523763 64621.794249283026 83909.11222494485 0.9114342400359885 0.8693775661431665 0.604774664487586 0.7855846184423231 0.900452928998561 0.7187132898133062 1.0002310355195208 0.8670113539064492 0.7701403642079291 1.0 16.35653987016569 -7.253122735917029 24.99035827675955 0.8982633030935885 0.7968728081415185 0.20829044044035094 0.10506573673870419 1141.7472576657194 3430799.2223245865 0.041752754102959415 0.031775762098064556 5.583123878348401e-08 7.253122735917029 -0.10139049495206998 RRS(ph)VTPPEEQQEAEEPK ddPTM_PC-9_AZD4547_30min_R2 1 RRSVTPPEEQQEAEEPK 17 2 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4;P30305-3 G8JLH2 CDC25B M-phase inducer phosphatase 2 1 RRS(0.5)VT(0.5)PPEEQQEAEEPK 75.018 0.043797 0.0 10031.0 6681.2 12253.0 13417.0 12369.0 10392.0 10095.0 10159.0 7726.0 8648.5 True False 13220.649342238485 8840.767242013006 12090.51721403202 10323.91794058362 10651.777854481275 9742.186597201695 10993.435443393693 8589.15998059604 8134.38058705839 8345.718647398522 1.5841235369658127 1.0593176711952537 1.4487089398587387 1.2370316298407364 1.2763164329535102 1.167327465590812 1.3172544999250007 1.0291696070144183 0.9746770686541165 1.0 13.026820569648153 -7.80528586827487 5.54896328737542 0.9949243916614138 1.287118813268208 0.4998435291177912 0.1360877098575442 0.1573037357261537 11.279584273661975 0.06964679413432066 0.033532531311138994 1.5657201174487795e-08 7.80528586827487 0.2921944216067943 RRS(ph)VTPPEEQQEAEEPK ddPTM_PC-9_Lapatinib_30min_R1 1 RRSVTPPEEQQEAEEPK 17 2 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4;P30305-3 G8JLH2 CDC25B M-phase inducer phosphatase 2 1 RRS(0.933)VT(0.067)PPEEQQEAEEPK 101.75 0.0028991 4435100.0 8316.2 6727.4 7315.9 5995.4 6098.2 5404.1 4047.7 4304.1 5242.8 5769.8 True False 8197.609462995702 6711.823118630225 6714.414942190673 6436.321716068105 5739.515865522493 5172.97924057239 4257.270100451794 4504.0841988895545 4652.300654868467 6767.102242224761 1.211391400568029 0.9918311972221122 0.9922142006802654 0.9511193248872936 0.8481497190495474 0.7644304837445038 0.6291127203439694 0.6655853624887432 0.6874878623584932 1.0 12.724322470643633 -5.950942073198627 0.8594042785228313 0.7154944349831146 1.134388994201928 0.6303380482400052 0.10780307272995156 0.43141362864253635 0.6294529674501055 0.04899133339547667 0.12260396856694038 1.1195872056054883e-06 5.950942073198627 0.41889455921881347 RRSS(ph)S(ph)SSS(ph)SSS(ph)ASR ddPTM_PC-9_AZD4547_30min_R2 1 RRSSSSSSSSSASR 14 2 F5H0Q6;A0A0A0MQS2;Q8N2M8-3;Q8N2M8;Q8N2M8-4 F5H0Q6 CLASRP CLK4-associating serine/arginine rich protein 4 RRS(0.439)S(0.538)S(0.457)S(0.459)S(0.145)S(0.96)S(0.228)S(0.182)S(0.577)AS(0.013)R 70.26 0.023476 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RRSSS(ph)S(ph)S(ph)SS(ph)SSASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RRSSSSSSSSSASR 14 2 F5H0Q6;A0A0A0MQS2;Q8N2M8-3;Q8N2M8;Q8N2M8-4 F5H0Q6 CLASRP CLK4-associating serine/arginine rich protein 4 RRS(0.391)S(0.437)S(0.59)S(0.591)S(0.496)S(0.496)S(0.418)S(0.315)S(0.239)AS(0.027)R 79.885 0.0048135 961840.0 0.0 0.0 0.0 0.0 464.66 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 373.61320858971953 0.0 0.0 0.0 0.0 0.0 0.0 RRSVT(ph)PPEEQQEAEEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RRSVTPPEEQQEAEEPK 17 2 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4;P30305-3 G8JLH2 CDC25B M-phase inducer phosphatase 2 1 RRS(0.333)VT(0.667)PPEEQQEAEEPK 115.58 0.00057766 0.0 8001.1 4113.0 5446.4 9289.6 9315.5 8458.1 9221.8 9732.5 6910.8 5974.1 True False 9355.528201071653 4521.31145812996 5576.26283158702 8769.133829289553 7490.1946468762835 8014.542346365927 8348.244343949698 9477.032187436143 7011.857376050891 7057.157039050422 1.3256794696934346 0.6406703766277995 0.7901571129466229 1.2425873167857813 1.0613614810368637 1.135661613028853 1.1829472261641778 1.342896599153946 0.9935810323124641 1.0 12.784871398512934 -5.762549688334617 24.999997936212168 1.1499988702074015 0.8910191130825893 0.2096215752896996 0.19070224448484646 37.650222709630256 847779.3016540523 0.05126781693918613 0.08115255638025107 1.7276283084490073e-06 5.762549688334617 -0.25897975712481225 RRSVT(ph)PPEEQQEAEEPK ddPTM_PC-9_Lapatinib_30min_R1 1 RRSVTPPEEQQEAEEPK 17 2 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4;P30305-3 G8JLH2 CDC25B M-phase inducer phosphatase 2 1 RRS(0.41)VT(0.59)PPEEQQEAEEPK 95.073 0.0051181 0.0 9496.5 11148.0 12034.0 8982.3 10974.0 11271.0 8582.4 8932.5 8509.1 7433.8 True False 9361.078168555186 11122.18749093108 11044.610972583352 9642.888306074412 10328.530895714122 10788.965603984267 9026.754677994279 9347.536559694472 7550.715553204638 8718.722425084134 1.0736754437350784 1.2756671159678254 1.2667694226401265 1.1059978556412593 1.184638114639193 1.2374479973056551 1.0353299758716854 1.0721222793836416 0.8660346304271495 1.0 13.08990103365173 -7.637050988600299 1.5760840417420015 0.9494381289542788 1.1942312676512847 0.6201719384376143 0.07642385982551768 0.25594811232069187 1.2203813105424814 0.05407694935615474 0.023506543778327543 2.3064763796007437e-08 7.637050988600299 0.24479313869700592 RRT(ph)LPPNVK ddPTM_PC-9_AZD4547_30min_R2 1 RRTLPPNVK 9 2 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 RRT(1)LPPNVK 70.919 0.017172999999999997 10349000.0 33531.0 32543.0 33613.0 40129.0 46626.0 40159.0 30115.0 46375.0 42569.0 40727.0 True False 44193.16051187305 43061.88833694981 33167.26965765597 30877.879036869635 40152.78472334414 37647.851381545704 32795.17665951469 39208.8093414845 44819.11043366409 39301.16012633401 1.1244747068486949 1.095690005041248 0.8439259693871483 0.7856734747170911 1.0216691974046714 0.957932317023881 0.8344582336524986 0.9976501766219458 1.140401715613294 1.0 15.26228427940752 -8.006330852442474 24.885090308665422 1.0698092454048846 0.9474453955996005 0.15627051830317806 0.10883204578321456 478.49958094158063 1880858.9371430073 0.06686679431562066 0.030365541681054143 9.855284083628472e-09 8.006330852442474 -0.12236384980528414 RRVS(ph)EVEEEKEPVPQPLPSDDTR ddPTM_PC-9_AZD4547_30min_R2 2 RRVSEVEEEKEPVPQPLPSDDTR 23 3 O43290 O43290 SART1 U4/U6.U5 tri-snRNP-associated protein 1 1 RRVS(1)EVEEEKEPVPQPLPSDDTR;RRVS(1)EVEEEKEPVPQPLPSDDTR 51.526 0.020478 46412000.0 73384.0 82038.0 91728.0 84244.0 82269.0 113048.0 102672.0 113954.0 96492.0 90278.0 True False 96718.58551797709 108555.1791594718 90511.62678598959 64822.84735682546 70847.36941630844 105979.09068903569 111809.60909798105 96345.02770241586 101592.37012767766 87117.39469848471 1.110209801988711 1.246079265055891 1.0389615885467236 0.7440861561709784 0.8132402221337404 1.2165089538757643 1.2834360977501296 1.105921820043726 1.1661548245248972 1.0 16.410673189529682 -6.795940346998941 24.9999183167764 1.1690890112151573 0.9937140595473533 0.22913478744019078 0.1490320554272739 302.9607274062798 219527.809764397 0.059180384238397915 0.052194543421015614 1.5997777527746677e-07 6.795940346998941 -0.17537495166780404 RRVS(ph)EVEEEKEPVPQPLPSDDTR ddPTM_PC-9_Lapatinib_30min_R1 4 RRVSEVEEEKEPVPQPLPSDDTR 23 3 O43290 O43290 SART1 U4/U6.U5 tri-snRNP-associated protein 1 1 RRVS(1)EVEEEKEPVPQPLPSDDTR;RRVS(1)EVEEEKEPVPQPLPSDDTR;RRVS(1)EVEEEKEPVPQPLPSDDTR;RRVS(1)EVEEEKEPVPQPLPSDDTR 63.869 0.0017968 115520000.0 132716.0 135873.0 129770.0 137414.0 190393.0 256144.0 288044.0 300253.0 248211.0 275872.0 True False 130823.44550286604 135558.39441651214 119100.81152668622 147519.8839596663 179194.45806704028 245189.31822082755 302957.50890988385 314203.8505074657 220254.8634022959 323556.10762366565 0.4043300139307811 0.4189641030488064 0.36809940755380416 0.45593292935533 0.5538280806476532 0.7577953635973764 0.9363368571062783 0.971095408506157 0.6807315893986416 1.0 18.30365638502122 -6.720464524419978 1.7318902167645223 0.8965432378222141 0.4052599488365294 0.8760561722283116 0.0833150401926025 0.11446173811916742 0.7099777862037481 0.03396656830421404 0.03197230210640583 1.903423713423359e-07 6.720464524419978 -0.49128328898568474 RRY(ph)Y(ph)EEGWLATGNGR ddPTM_PC-9_AZD4547_30min_R2 1 RRYYEEGWLATGNGR 15 2 Q9NRJ4-2;Q9NRJ4 Q9NRJ4-2 TULP4 Tubby-related protein 4 2 RRY(0.999)Y(0.999)EEGWLAT(0.003)GNGR 60.255 0.045850999999999996 0.0 13034.0 13918.0 17307.0 16618.0 14268.0 22383.0 17845.0 19365.0 21940.0 19617.0 True False 17178.540875958173 18416.72131867584 17077.49787180709 12786.97684554063 12287.134483607311 20983.38747162871 19433.17042965432 16372.584213430673 23099.70360860226 18930.21480095009 0.9074667697429403 0.9728743974818249 0.9021291121826037 0.6754797544557637 0.649075280592729 1.1084600831140898 1.0265689340555708 0.8648916235545805 1.2202557578714273 1.0 14.20840316092954 -6.780304547508071 24.999975126349153 1.0344993764792088 0.8261976826918155 0.43845330986634745 0.12568539242780152 273.2071857209069 362049.7210866005 0.0474116217333189 0.04188128723945247 1.6584235357935068e-07 6.780304547508071 -0.20830169378739327 RS(ph)AAGSPPAVAAAGSGNGAGGGGGVGCAPAAGAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSAAGSPPAVAAAGSGNGAGGGGGVGCAPAAGAGR 35 1 Q86VQ1 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 RS(0.952)AAGS(0.048)PPAVAAAGSGNGAGGGGGVGCAPAAGAGR 86.191 4.3013e-12 3169600.0 4100.0 5213.6 5111.2 4982.0 7569.0 6393.0 7466.0 5361.2 5171.7 5109.5 True False 4794.049021308794 5731.17175251796 5233.070392333941 4702.874691861926 6085.908784521125 6057.739825766702 6758.766430840889 5220.4741806609445 5247.326328604848 6035.811903220253 0.7942674652851677 0.9495278919245711 0.8670035574736796 0.7791619035299672 1.0082999407708753 1.0036329698304134 1.1197775111638124 0.8649166449132873 0.8693654495437922 1.0 12.559332131858747 -6.2757835285806625 24.93585759407718 0.9793152376278301 0.8561724190836904 0.38171234204565374 0.08084576478093015 936.4342367615695 1627893.2992135736 0.026630154106480175 0.030336361485764955 5.299275171922315e-07 6.2757835285806625 -0.12314281854413978 RS(ph)ASPDDDLGSSNWEAADLGNEER ddPTM_PC-9_AZD4547_30min_R2 1 RSASPDDDLGSSNWEAADLGNEER 24 1 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 RS(0.541)AS(0.418)PDDDLGS(0.031)S(0.01)NWEAADLGNEER 62.858000000000004 0.0010835 26722000.0 18996.0 14330.0 24546.0 43119.0 35258.0 29702.0 23554.0 35880.0 32600.0 28594.0 True False 25036.33285865438 18961.89226157672 24220.504001928522 33178.58073190914 30363.035297380593 27844.729244619415 25650.26036985587 30335.570440376614 34323.16944578094 27592.93276333622 0.9073458437126013 0.6872010461596205 0.8777792563649207 1.2024303837682229 1.1003917400808194 1.0091253975589636 0.9295952912964129 1.0993963816954115 1.2439116109972712 1.0 14.752011183767248 -5.589951113432141 6.0397929797625665 1.0779472141112585 0.7934069057746583 0.5888345619145405 0.10067553200350343 0.133105489852076 8.840621864721133 0.028239504541981122 0.049721149817184826 2.5706851368954465e-06 5.589951113432141 -0.28454030833660016 RS(ph)ASPDDDLGSSNWEAADLGNEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSASPDDDLGSSNWEAADLGNEER 24 1 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 RS(0.556)AS(0.442)PDDDLGS(0.002)S(0.001)NWEAADLGNEER;RS(0.5)AS(0.5)PDDDLGSSNWEAADLGNEER 79.069 7.690899999999999e-05 35586000.0 13555.0 12386.8 14949.599999999999 16731.2 14660.8 15640.0 14198.7 14724.599999999999 14226.7 12676.599999999999 True False 15849.5937765465 13616.479642490678 15306.05516067372 15793.805107282262 11788.121483433399 14819.81086735355 12853.696346314022 14338.094852003307 14434.738573227878 14974.76723208961 1.0584200429227517 0.9092949113300244 1.0221230770034402 1.0546945313071394 0.7871989795055038 0.989652168722596 0.8583570046264011 0.9574836543220537 0.9639374255043845 1.0 13.8702459574737 -4.7491887262232275 24.78819691226849 0.9468042108130584 1.0584203274646053 0.15766582453239175 0.07555811053306341 985.9572579078645 1994867.8658202137 0.018534512436111785 0.30927930782326285 1.7816043884286708e-05 4.7491887262232275 0.11161611665154691 RS(ph)ASPDDDLGSSNWEAADLGNEER ddPTM_PC-9_Lapatinib_30min_R1 2 RSASPDDDLGSSNWEAADLGNEER 24 1 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 RS(0.591)AS(0.409)PDDDLGSSNWEAADLGNEER;RS(0.5)AS(0.5)PDDDLGSSNWEAADLGNEER 91.76700000000001 4.8105e-06 60196000.0 65701.0 48879.0 59012.0 51002.0 58355.0 58108.0 44450.0 50925.0 53687.0 42636.0 True False 64764.09169191229 48765.82367861681 54160.261152907464 54752.85721768445 54922.67363034418 55622.85629636391 46751.40350447962 53291.16141085257 47640.20471082693 50005.57579110108 1.2951374055258376 0.9752077224815219 1.0830844420062802 1.0949350417724455 1.0983309913235344 1.1123330831891445 0.9349238112922486 1.0657043853164907 0.9526978533322861 1.0 15.609801348790372 -4.752053696808874 24.96323517835772 1.0419051170652385 1.2951379127208684 0.6086727983172271 0.062310377454981185 262.55999280101105 698283.9555277019 0.015638625570500896 0.19450432254681113 1.769890112970286e-05 4.752053696808874 0.25323279565562995 RS(ph)ASPHDVDLCLVSPCEFEHR ddPTM_PC-9_AZD4547_30min_R2 1 RSASPHDVDLCLVSPCEFEHR 21 1 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 RS(0.596)AS(0.404)PHDVDLCLVSPCEFEHR 65.374 0.0015876 2203400.0 2942.1 2286.2 5548.4 7178.9 5626.3 4446.0 3070.9 5515.2 2941.0 5738.1 True False 3877.626600518375 3025.16944092231 5474.8245907398405 5523.9155178993615 4845.185362007271 4167.990917163082 3344.2041508784228 4662.952566687989 3096.4552558295027 5537.21086554171 0.700285160648117 0.5463345201007358 0.988733267286225 0.9975989089154821 0.8750227288902899 0.7527238926551741 0.6039510201227015 0.8421121535583437 0.5592084771592989 1.0 12.434943747631852 -10.455360035256385 17.949589571041013 0.9999999999989451 0.7707172611592021 0.17069244856819465 0.15593656521530375 0.0 0.0 0.16021955568932328 0.03885895008215359 3.504612170008417e-11 10.455360035256385 -0.22928273883974293 RS(ph)ASPHDVDLCLVSPCEFEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSASPHDVDLCLVSPCEFEHR 21 1 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 RS(0.6)AS(0.4)PHDVDLCLVSPCEFEHR 75.682 0.00051969 1950200.0 2157.1 2213.9 2433.3 3474.0 2318.2 2608.2 3346.3 2158.4 2714.9 1145.5 True False 2522.2544253329756 2433.6813608446178 2491.319100341638 3279.363042859961 1863.9653513379408 2471.4214005263107 3029.314238885998 2101.744287013836 2754.6002764138107 1353.1700822269893 1.8639596444387518 1.7985036713488147 1.8410982721710283 2.4234670023615403 1.3774804629661237 1.8263937645288102 2.238679585570265 1.553200380808653 2.0356644834183797 1.0 10.402127470143473 -11.120587242413393 2.7127533970261086 0.9286921105562983 1.8804166207231425 0.46216277844989717 0.28614999649170136 34808967.998564936 33172689.92665025 17704102.852541037 0.07017716701601105 7.57552538092162e-12 11.120587242413393 0.9517245101668442 RS(ph)ASPHDVDLCLVSPCEFEHR ddPTM_PC-9_Lapatinib_30min_R1 2 RSASPHDVDLCLVSPCEFEHR 21 1 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 RS(0.605)AS(0.395)PHDVDLCLVSPCEFEHR;RS(0.5)AS(0.5)PHDVDLCLVSPCEFEHR 85.51 0.00016819 4810600.0 13989.9 15360.2 21137.2 15031.2 17076.5 15999.0 16376.0 14193.9 17187.5 14919.5 True False 13790.401460566543 15324.634400627872 19399.38100795154 16136.644590613274 16072.093843690744 15314.760065490585 17223.86915161661 14853.400411379494 15251.662757601245 17498.31569601586 0.7880987919143806 0.8757776843697644 1.1086427599639506 0.9221827329522566 0.9184937637940863 0.875213382335853 0.9843158307824029 0.8488474359141561 0.8716074748310692 1.0 14.094928441381422 -7.772927062219216 24.99723779047135 0.8951706334354198 0.9276340511172622 0.0026880287079437126 0.08642198908116913 1130.5983140086173 2460150.119668424 0.0477825665979687 0.023279385946604485 1.6868362980765707e-08 7.772927062219216 0.032463417681842355 RS(ph)CTLPNYTK ddPTM_PC-9_AZD4547_30min_R2 1 RSCTLPNYTK 10 1 A0A2R8YCU7;J3KTL8;A6NHR9-3;A6NHR9-2;A6NHR9 A0A2R8YCU7 SMCHD1 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 1 RS(0.896)CT(0.104)LPNYTK 89.23100000000001 0.0043466 2345100.0 23538.0 18778.0 31510.0 39879.0 33591.0 33670.0 26726.0 29979.0 30078.0 27520.0 True False 31022.594379185477 24847.621276195918 31092.15681173173 30685.51267440814 28927.46947286607 31564.609577346164 29104.562224877627 25346.43439888655 31667.861674545973 26556.533176436064 1.1681718458157861 0.9356500380194022 1.1707912552124906 1.1554788597796255 1.0892788332226198 1.188581708600196 1.0959473524466838 0.9544331042945301 1.19246971975413 1.0 14.696779201851225 -10.724413438137569 4.422274421410368 0.9999715663617884 1.101252038322796 0.1131691298425207 0.08795053577657701 2.514751207957989e-05 4.540365250774088e-06 0.08284532029807058 0.020087029489834228 1.886194880947416e-11 10.724413438137569 0.10128047196100753 RS(ph)DSASSEPVGIYQGFEK ddPTM_PC-9_AZD4547_30min_R2 1 RSDSASSEPVGIYQGFEK 18 1 Q05655;Q05655-2 Q05655 PRKCD Protein kinase C delta type;Protein kinase C delta type regulatory subunit;Protein kinase C delta type catalytic subunit 1 RS(0.701)DS(0.297)AS(0.001)S(0.001)EPVGIYQGFEK 65.28699999999999 0.022181 11765000.0 10104.0 7884.1 12154.0 20763.0 16045.0 12769.0 10643.0 14729.0 11152.0 12019.0 True False 13316.861823744162 10432.48114302142 11992.830018717472 15976.411135152242 13817.428706860055 11970.552411438463 11590.206381777016 12452.971488748795 11741.471952740767 11598.218468298883 1.1481816677399899 0.8994899666303283 1.034023462439268 1.377488377100342 1.1913406136146585 1.0321026840593899 0.9993091967922689 1.073696923608241 1.0123513352359619 1.0 13.501615598321504 -6.85351409279041 9.08603728687035 1.0260092364547386 1.1255929943040939 0.1769408397405139 0.11474213316230782 0.6488686979718016 57.90180646459738 0.04516596281143987 0.03985169197373747 1.4011541169626123e-07 6.85351409279041 0.09958375784935525 RS(ph)DSASSEPVGIYQGFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSDSASSEPVGIYQGFEK 18 1 Q05655;Q05655-2 Q05655 PRKCD Protein kinase C delta type;Protein kinase C delta type regulatory subunit;Protein kinase C delta type catalytic subunit 1 RS(0.528)DS(0.364)AS(0.087)S(0.021)EPVGIYQGFEK;RS(0.292)DS(0.292)AS(0.123)S(0.292)EPVGIYQGFEK 103.02 0.00019617 34112000.0 126984.0 102851.0 105768.0 114156.0 132145.0 110145.0 107124.0 131586.0 89853.0 82020.0 True False 148479.88315167706 113061.36756142078 108289.91024737347 107760.20941874543 106252.13586081966 104368.80230080932 96976.43920940232 128132.00692689166 91166.93013982466 96889.57673003725 1.5324649788220823 1.1669095002493701 1.1176631574013465 1.112196100505186 1.0966312316222542 1.0771932938835245 1.000896510050891 1.3224539857770765 0.9409364063364879 1.0 16.564053850053376 -4.620005657800002 2.058528489847396 1.0922759562589262 1.8144654387521413 0.6550973537216006 0.09714349152302013 0.7522483275084053 2.4015648063872783 0.024142524371697168 1.187992919335289 2.3988016682690112e-05 4.620005657800002 0.7221894824932151 RS(ph)DSLLSFR ddPTM_PC-9_AZD4547_30min_R2 4 RSDSLLSFR 9 1 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 RS(0.786)DS(0.214)LLSFR;RS(0.957)DS(0.043)LLSFR;RS(0.954)DS(0.045)LLSFR;RS(0.566)DS(0.433)LLSFR 84.605 0.0059955 76134000.0 24410.69 26290.550000000003 33193.2 44385.0 46102.1 40723.5 31188.760000000002 41323.0 31852.300000000003 40379.4 True False 32172.78164610582 34788.45614777359 32753.03647994842 34152.723991414154 39701.619195171865 38177.05310730786 33964.49921936598 34937.47985807362 33535.94755024073 38965.72949653283 0.8256686596607553 0.8927962236885381 0.8405600742791889 0.8764810625309366 1.0188855619578356 0.9797597427427825 0.8716505415967674 0.896620705155343 0.8606523728299442 1.0 15.249918205545098 -6.019004825727224 24.627907665378647 0.933004748604739 0.8572426716572001 0.3611224936941717 0.05187696334132174 802.8438432428279 1040386.95242931 0.01617172300590641 0.02124325012447092 9.571834353507604e-07 6.019004825727224 -0.07576207694753889 RS(ph)DSLLSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSDSLLSFR 9 1 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 RS(0.998)DS(0.002)LLSFR;RS(1)DSLLSFR 112.64 0.00098758 53171000.0 20602.1 18647.0 21638.1 29366.0 29188.0 21361.7 25419.0 25594.0 23341.0 18918.6 True False 24089.628619977033 20498.15092627021 22154.03436695122 27720.718225856544 23468.820927811168 20241.454846876353 23011.128302376717 24922.18461908458 23682.317968166302 22348.3924204448 1.077913264040384 0.9172091907388403 0.991303264689599 1.2403898098950965 1.0501346354712018 0.9057230813773891 1.0296547451585658 1.1151667712924718 1.05968776288809 1.0 14.447883437782878 -5.569642788737562 24.999993774261696 1.059024664410636 0.9867316158187062 0.09167600193144254 0.0878180299249082 264.59386191817634 141450.24066762457 0.024983614188968432 0.04327290539388545 2.693749527099992e-06 5.569642788737562 -0.07229304859192986 RS(ph)DSLLSFR ddPTM_PC-9_Lapatinib_30min_R1 3 RSDSLLSFR 9 1 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 RS(0.836)DS(0.164)LLSFR;RS(0.956)DS(0.044)LLSFR;RS(0.966)DS(0.034)LLSFR 117.86 0.00084014 75443700.0 32702.8 28572.7 36985.6 37811.200000000004 37540.3 33699.7 32569.1 34493.4 36330.2 25192.300000000003 True False 32236.452075040983 28506.541668651473 33944.78673654468 40591.961782465616 35332.25336106949 32258.44238883762 34255.368636169784 36096.08928834761 32238.310302033726 29546.755488370305 1.0910318761641815 0.9647943131986771 1.1488498881004194 1.3738212914254744 1.1958082292648469 1.0917761309371055 1.1593614280137392 1.2216599992698063 1.091094767231645 1.0 14.850712097166165 -5.387361158335691 6.331480766859013 1.176053058489983 1.029598229318864 0.218358936887722 0.09762802368064545 0.29824072168608223 13.956820721670146 0.025684409835651942 0.05414859777479905 4.098631199570431e-06 5.387361158335691 -0.14645482917111918 RS(ph)EDLDNATEVNPK ddPTM_PC-9_AZD4547_30min_R2 1 RSEDLDNATEVNPK 14 1 O95171-2;O95171;O95171-3 O95171-2 SCEL Sciellin 1 RS(0.919)EDLDNAT(0.081)EVNPK 103.77 0.0016625999999999998 2231700.0 5088.1 5558.2 5789.1 7129.7 7396.2 4830.9 4137.6 6541.2 5621.6 5854.3 True False 6706.009960945435 7354.7794534749255 5712.332751469257 5486.057817766941 6369.365297705099 4528.823059316946 4505.8383844067075 5530.407841822505 5918.74629927614 5649.342738910239 1.1870425058046712 1.301882323906173 1.0111499718587031 0.9710966516478702 1.1274524474919276 0.8016548594448631 0.7975863020971332 0.9789471266686368 1.047687593551435 1.0 12.463867314584178 -5.371804881316292 4.229217692885452 0.9555777285204352 1.2435913152377245 0.5619721052196116 0.09845833457021512 0.16433231960554553 4.90002588820743 0.028200350091529186 0.06286811631186405 4.248103787694838e-06 5.371804881316292 0.28801358671728927 RS(ph)ESPPAELPSLR ddPTM_PC-9_AZD4547_30min_R2 3 RSESPPAELPSLR 13 1 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 RS(0.651)ES(0.349)PPAELPSLR;RS(0.5)ES(0.5)PPAELPSLR;RS(0.413)ES(0.173)PPAELPS(0.413)LR 137.32 2.713e-05 27498000.0 49683.0 69878.0 69065.0 105477.0 90004.0 79641.0 68045.0 94522.0 66120.0 62157.0 True False 65481.16052940228 92464.69696123233 68149.1529737307 81160.90725340534 77508.49818212724 74661.03568011345 74100.87317936831 79915.79679947805 69614.96821334472 59980.90234911834 1.0917001572978968 1.5415689551157856 1.1361808559842785 1.3531124753843975 1.292219609018045 1.2447467903291871 1.2354077760962114 1.3323540271923358 1.1606188884613868 1.0 15.872215605737528 -8.552386743962797 3.6479123699485525 1.0002948951302773 1.2822715477051763 0.35567163052280526 0.11679116646270722 0.21956755522800206 8.549001242085346 0.10211300033157408 0.02687744135060768 2.802936480801893e-09 8.552386743962797 0.281976652574899 RS(ph)ESPPAELPSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSESPPAELPSLR 13 1 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 RS(0.742)ES(0.258)PPAELPSLR 81.60600000000001 0.0052472000000000005 7790500.0 14135.0 16400.0 18293.0 19920.0 20207.0 20162.0 17444.0 19446.0 18243.0 11466.0 True False 16527.77632102433 18028.08361617587 18729.17449658884 18803.946981511355 16247.583407163222 19104.669226827504 15791.578036376695 18935.563104740126 18509.769362634775 13544.695035193936 1.2202398265947876 1.331006978697748 1.3827682681613562 1.3882886940349717 1.1995532837724452 1.410490910071196 1.1658865700072654 1.3980058654357885 1.3665696654328363 1.0 13.72544029053741 -11.024942280853498 3.216777513482058 0.9920063373501972 1.3195420812528416 0.553771756235259 0.08565232375182558 46374755.92678532 50975217.85146064 3211753.374419853 0.020217983098496994 9.441863533790733e-12 11.024942280853498 0.3275357439026444 RS(ph)ESPPAELPSLR ddPTM_PC-9_Lapatinib_30min_R1 2 RSESPPAELPSLR 13 1 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 RS(0.648)ES(0.352)PPAELPSLR;RS(0.78)ES(0.22)PPAELPSLR 108.32 0.00041716 21957700.0 36064.0 43057.0 52279.0 43686.0 46354.0 49387.0 41791.0 49863.0 57682.0 35941.0 True False 35549.72074667239 42957.30416191418 47980.82242277589 46898.81417222387 43627.548855470406 47274.83313671997 43954.73349506654 52179.81701383099 51185.24574161196 42153.35396162781 0.8433426383825424 1.0190720340075006 1.138244479109606 1.1125761004667827 1.0349721850172244 1.1214963625374685 1.042733955050849 1.2378568277468567 1.2142627082107365 1.0 15.363359804342041 -4.827929144576481 2.3273353221446333 1.116297611572206 0.7924847146292046 0.5709132210688893 0.07131607340867233 0.3838393658646993 2.746642699649446 0.01936820420389321 0.24734360544160236 1.4861780934184385e-05 4.827929144576481 -0.3238128969430015 RS(ph)ETPPHWR ddPTM_PC-9_AZD4547_30min_R2 1 RSETPPHWR 9 1 Q13427;E9PG73;C9JM79 Q13427 PPIG Peptidyl-prolyl cis-trans isomerase G 1 RS(0.77)ET(0.23)PPHWR 53.211000000000006 0.037104000000000005 13373000.0 1228.2 2434.8 2424.6 3126.3 4203.6 2837.6 1236.2 1267.4 2258.9 2160.0 True False 1618.7420518529868 3221.8014848909293 2392.4482197945026 2405.5798358535117 3620.0026994176956 2660.1644234237433 1346.2194051632764 1071.552451954663 2378.3008423642514 2084.379057452833 0.7766063692038496 1.5456888579700359 1.1477990105687104 1.154099024000555 1.7367295485310794 1.2762383185112862 0.6458611260508406 0.5140871321477049 1.1410116762881886 1.0 11.025401949312597 -7.249434443140866 23.135146070201674 0.7847472664880988 1.2952637185374927 0.360943501321645 0.2888684689849323 267.86244371148945 516208.00567469955 0.10910748914318662 0.08370299220485032 5.6307410715479e-08 7.249434443140866 0.5105164520493939 RS(ph)ETPPHWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSETPPHWR 9 1 Q13427;E9PG73;C9JM79 Q13427 PPIG Peptidyl-prolyl cis-trans isomerase G 1 RS(0.636)ET(0.364)PPHWR;RS(0.5)ET(0.5)PPHWR 63.073 0.021643 24868000.0 2828.5 4293.6 4889.5 5092.139999999999 6252.9 6378.6 6579.1 4661.46 8098.299999999999 4217.700000000001 True False 3307.309184578518 4719.840232586141 5006.0842235320115 4806.8439047406255 5027.68913181823 6044.094987116452 5955.880019440832 4539.101614225129 8216.72231702161 4982.3356227051745 0.6638069843200977 0.9473147916967282 1.004766559827606 0.9647772187074654 1.0091028610971877 1.2131047454074946 1.1953992003868799 0.9110389098518036 1.6491707783748848 1.0 12.282606493094207 -4.032014857780347 0.40287004567811574 1.2058627547853458 1.6050648500739753e-13 0.3964182776103854 0.19012582546700219 10.685022447775175 0.8590991502475775 0.14096897429571192 6.999783643475164 9.289346061725282e-05 4.032014857780347 -1.2058627547851852 RS(ph)FNGTDNHIR ddPTM_PC-9_AZD4547_30min_R2 1 RSFNGTDNHIR 11 1 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 RS(1)FNGTDNHIR 79.65899999999999 0.0078086 857460.0 5670.7 3699.9 8381.6 7963.9 7539.6 7276.5 4712.6 8712.1 6344.0 5199.0 True False 7473.864642112622 4895.820319512049 8270.45450755985 6127.945896028464 6492.856682969274 6821.499304709214 5132.012270484114 7365.845129141724 6679.330888467313 5016.984592452442 1.48971249649766 0.9758491837661466 1.64849111157366 1.2214400469252693 1.294175129167655 1.3596811349533515 1.0229276522404953 1.4681817321549904 1.3313437116222577 1.0 12.292604792143091 RS(ph)GS(ph)S(ph)RS(ph)PGSKAR ddPTM_PC-9_Lapatinib_30min_R1 1 RSGSSRSPGSKAR 13 3 Q494U1;Q494U1-2 Q494U1 PLEKHN1 Pleckstrin homology domain-containing family N member 1 4 RS(0.999)GS(0.999)S(0.999)RS(0.999)PGS(0.004)KAR 75.294 0.027839 8028900.0 0.0 0.0 844.46 0.0 627.04 0.0 872.91 0.0 0.0 0.0 True False 0.0 0.0 775.031758509867 0.0 590.1587400080721 0.0 918.1050086185666 0.0 0.0 0.0 0.0 RS(ph)HLVEAHVR ddPTM_PC-9_AZD4547_30min_R2 2 RSHLVEAHVR 10 1 Q9UNX9 Q9UNX9 KCNJ14 ATP-sensitive inward rectifier potassium channel 14 1 RS(1)HLVEAHVR;RS(1)HLVEAHVR 63.184 0.025791 9240200.0 43795.0 59879.0 60980.0 78042.0 68561.0 64888.0 54669.0 74354.0 53215.0 58410.0 True False 57720.89900741045 79233.71575233433 60171.36535637585 60050.62263688054 59042.48859900486 60830.54310231173 59534.435092113854 62864.29778494318 56027.83625942434 56365.08367862031 1.024054170424383 1.4057233766227561 1.067529069937304 1.0653869154044773 1.0475011256197266 1.0792238586773393 1.0562289844465484 1.1153056765315879 0.9940167316858984 1.0 15.782514116590578 -5.474879559088115 24.965327550620728 1.0578524243957894 1.2203232867682852 0.33117786871948474 0.09178280116957141 378.4145088361921 196819.9693631313 0.02167837886532593 0.045125277209134326 3.3505834648059183e-06 5.474879559088115 0.16247086237249575 RS(ph)HLVEAHVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSHLVEAHVR 10 1 Q9UNX9 Q9UNX9 KCNJ14 ATP-sensitive inward rectifier potassium channel 14 1 RS(1)HLVEAHVR 65.627 0.02215 3746200.0 15105.0 21540.0 22620.0 19397.0 24732.0 20507.0 20419.0 19236.0 20206.0 14615.0 True False 17661.978162651052 23678.34884709926 23159.346586827716 18310.248975922488 19885.94214014751 19431.57681948971 18484.764499241912 18731.075382226714 20501.474524003628 17264.583807723655 1.0230178937038503 1.371498387149436 1.3414367148814166 1.0605670649141878 1.1518344352587948 1.1255166667149317 1.070675360906898 1.084942190952034 1.1874873296877209 1.0 14.075527935532213 -5.770844652782152 24.998267040888535 1.1031682324142655 1.2579357447537667 0.31417557666421214 0.09943812368332083 213.9886776778683 568761.153815633 0.027258150916853 0.04104584175273648 1.6949439738048749e-06 5.770844652782152 0.15476751233950115 RS(ph)HLVEAHVR ddPTM_PC-9_Lapatinib_30min_R1 1 RSHLVEAHVR 10 1 Q9UNX9 Q9UNX9 KCNJ14 ATP-sensitive inward rectifier potassium channel 14 1 RS(1)HLVEAHVR 61.765 0.028623000000000003 5461900.0 40355.0 35264.0 43620.0 44464.0 45095.0 46736.0 40607.0 49154.0 44970.0 32998.0 True False 39779.530299799364 35182.34837461371 40033.73197806926 47734.03088755584 42442.60076018119 44737.21022693718 42709.43176842304 51437.87428549922 39905.00504490634 38701.66033292881 1.0278507422575216 0.9090656078307644 1.0344189792810279 1.233384575155861 1.0966609803060425 1.1559506709037262 1.1035555426050874 1.3290870170170443 1.0310928446383392 1.0 15.240107840045765 -5.558945275791545 6.643567083637543 1.1468723235630667 0.968854356485261 0.34659555591648017 0.09340164751652313 0.16269121732183983 20.774365048117936 0.0237487031349905 0.04205454328499697 2.76092573067589e-06 5.558945275791545 -0.1780179670778057 RS(ph)HSPSIDGTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSHSPSIDGTPK 12 1 A0A0C4DH56;Q9BWT3-2;Q9BWT3 A0A0C4DH56 PAPOLG Poly(A) polymerase gamma 1 RS(0.706)HS(0.291)PS(0.002)IDGT(0.001)PK 54.501000000000005 0.038782 3142700.0 16883.0 23988.0 26161.0 24470.0 36245.0 35451.0 32980.0 27616.0 25649.0 23139.0 True False 19740.958445550325 26369.370108830888 26784.777456144995 23099.025232810392 29143.052436909536 33591.887152081224 29855.89564547715 26891.10926157067 26024.068101859302 27333.917531776784 0.7222147510542776 0.9647124338534874 0.9799099388152689 0.845068227265881 1.0661864477724263 1.2289452147877924 1.092265519963191 0.9838000436749934 0.9520797035992105 1.0 14.738404623114766 -3.9334992003946874 0.7162061406946911 1.0449788544208711 2.5270436865380615e-10 0.4723577211575761 0.09414223500820437 8.587269308307269 1.3691854764522353 0.04143455906687983 9.61026394910906 0.00011654691966496409 3.9334992003946874 -1.0449788541681668 RS(ph)HSPSIDGTPK ddPTM_PC-9_Lapatinib_30min_R1 2 RSHSPSIDGTPK 12 1 A0A0C4DH56;Q9BWT3-2;Q9BWT3 A0A0C4DH56 PAPOLG Poly(A) polymerase gamma 1 RS(0.722)HS(0.276)PS(0.002)IDGTPK;RS(0.597)HS(0.393)PS(0.009)IDGTPK 79.317 0.0071126 6167700.0 49881.0 48187.0 57470.0 49077.0 43157.0 61249.0 46399.0 53750.0 54436.0 38097.0 True False 49169.687792944926 48075.42596210049 52745.03844061534 52686.28629607267 40618.59010992658 58629.523048392584 48801.313187949374 56247.4212240221 48304.84444350728 44682.015688938394 1.1004357577609802 1.0759457741742429 1.180453424657676 1.1791385299816686 0.9090590360269318 1.3121503617149277 1.0921913981609108 1.2588380438250208 1.081080244449799 1.0 15.447406649498726 -6.7861892547837765 24.999857628633666 1.1614879440601698 1.0983683430651954 0.060838075166573136 0.10914618953941486 652.8682556785672 659457.2080095992 0.036640072269539005 0.03232755021361545 1.6361033927021686e-07 6.7861892547837765 -0.06311960099497438 RS(ph)LSPILPGR ddPTM_PC-9_Lapatinib_30min_R1 1 RSLSPILPGR 10 1 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 RS(0.756)LS(0.244)PILPGR 68.676 0.018506 4673000.0 13207.0 10582.0 9983.6 8750.1 8814.1 8070.8 5825.7 6469.7 8455.5 7574.3 True False 13018.66575813283 10557.498029156148 9162.78694581047 9393.611543477915 8295.671967187338 7725.630697953707 6127.326240630978 6770.305880801039 7503.152549637669 8883.507662879654 1.4654870859775602 1.1884379942926573 1.031437951485966 1.0574214488191152 0.9338284247619183 0.8696599351442881 0.6897417634066362 0.7621207903147567 0.8446159821519721 1.0 13.116913723471752 -4.051673070108707 0.5107858522890498 0.8073746280694352 2.536686940663528 0.8298796224373087 0.08772418303201404 3.3816012465120746 0.3865513250992 0.05237039487427982 4.1031720243828556 8.878241002268813e-05 4.051673070108707 1.7293123125940928 RS(ph)LSVEHLETK ddPTM_PC-9_Lapatinib_30min_R1 1 RSLSVEHLETK 11 1 J3KN34;P26045-2;P26045 J3KN34 PTPN3 Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 3 1 RS(0.59)LS(0.41)VEHLETK 70.529 0.014668 7960900.0 57535.0 49410.0 56057.0 46731.0 52201.0 45534.0 43386.0 50490.0 54883.0 40078.0 True False 56714.540349373194 49295.59418074133 51448.20984627763 50167.75363004613 49130.63981111472 43586.61696493829 45632.314790671604 52835.94972280701 48701.49859638862 47005.428899421844 1.2065529807360351 1.0487212931557286 1.0945163367482948 1.0672757339878922 1.0452120310664588 0.9272677217391456 0.9707881804102179 1.1240393069460297 1.036082421470845 1.0 15.520539770253825 -1.5228791916486488 0.7154839708570706 1.023092662918987 24.63684900678665 0.4871386443725687 0.05372743700879955 302.2992308434602 1.506799659308559 0.022478276498950244 11448.65422662073 0.02999996916598526 1.5228791916486488 23.613756343867664 RS(ph)LTGPR ddPTM_PC-9_Lapatinib_30min_R1 1 RSLTGPR 7 1 M0R202;A0A0B4J2G2;Q9NWS9-2;Q9NWS9 M0R202 ZNF446 Zinc finger protein 446 1 RS(1)LTGPR 73.616 0.01642 11977000.0 3009.5 2251.0 3400.0 2374.5 1940.5 2138.9 849.99 2753.1 3006.4 2093.3 True False 2966.5839781252917 2245.787947801028 3120.4651243795415 2549.1286510997934 1826.3636051697881 2047.4242330194259 893.998323166988 2881.019076685682 2667.7875732045027 2455.1241158530784 1.208323424045915 0.9147349957990566 1.271000966602977 1.038289117295421 0.7438986865782891 0.8339391967187819 0.3641356937493776 1.173471865671695 1.0866202470083801 1.0 11.26158024476195 -6.079870675611831 5.706462593923218 0.8503419061638168 1.1167999544299148 0.2214825766132018 0.22448379278866012 0.35300645261672875 19.33093282660304 0.069186939305402 0.09079827154805555 8.320114909393142e-07 6.079870675611831 0.266458048266098 RS(ph)NSAPLIHGLSDTSPVFQAEAPSAR ddPTM_PC-9_AZD4547_30min_R2 1 RSNSAPLIHGLSDTSPVFQAEAPSAR 26 1 Q96E09 Q96E09 FAM122A Protein FAM122A 1 RS(0.699)NS(0.3)APLIHGLS(0.001)DTSPVFQAEAPSAR 57.095 0.035026 0.0 3441.2 3298.6 4393.4 8767.5 6861.5 5956.9 2677.0 3459.3 4367.3 3444.7 True False 4535.430018593468 4364.807942361268 4335.140645403432 6746.288331524699 5908.899163111261 5584.414101315513 2915.2478139638324 2924.7446718058754 4598.146561980342 3324.1021014850803 1.364407554318868 1.3130787831129618 1.3041538776641846 2.029506954227043 1.7775925596483313 1.6799767067385243 0.8770030898453487 0.8798600592019158 1.383274767621027 1.0 11.698748980562147 -7.258239592002514 24.992317468716056 1.0250228079131876 1.5832037153605538 0.5340947251355381 0.2483947288026436 242.52988108437435 1894317.7302467353 0.10752205347192204 0.07976147771045826 5.517729526591289e-08 7.258239592002514 0.5581809074473663 RS(ph)NSSEALLVDR ddPTM_PC-9_Lapatinib_30min_R1 2 RSNSSEALLVDR 12 1 Q96HB5-2;Q96HB5;Q96HB5-5;Q96HB5-3;Q96HB5-4 Q96HB5-2 CCDC120 Coiled-coil domain-containing protein 120 1 RS(0.885)NS(0.087)S(0.027)EALLVDR;RS(0.861)NS(0.108)S(0.031)EALLVDR 83.85600000000001 0.004843899999999999 5906100.0 15043.7 18648.6 20769.4 16043.8 17514.9 16337.6 14032.4 12453.1 19138.7 12937.8 True False 14829.17407932329 18605.42031246657 19061.820104202478 17223.714572547866 16484.7080176183 15638.87893280573 14758.929010939484 13031.716488276656 16983.09806655436 15174.08149146513 0.9772699644234916 1.2261315667067851 1.256209156048362 1.1350746061457215 1.0863727090756927 1.030631009962747 0.9726406846596183 0.8588141888921925 1.1192175339315753 1.0 13.88932157030959 -6.657916951653577 1.8072317590439408 0.9783951106490207 1.161736038197873 0.38597268220266556 0.09103296885378938 0.33135096287282084 2.2261060886278967 0.03639560436707386 0.035910110945622936 2.198280200670445e-07 6.657916951653577 0.18334092754885223 RS(ph)NSSGNLHMAGLTASPTPPSSSIITY ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSNSSGNLHMAGLTASPTPPSSSIITY 27 1 Q9UKI8-5;Q9UKI8;Q9UKI8-2;Q9UKI8-4;Q9UKI8-3 Q9UKI8-5 TLK1 Serine/threonine-protein kinase tousled-like 1 1 RS(0.934)NS(0.045)S(0.02)GNLHMAGLTASPTPPSSSIITY 56.00899999999999 0.0013994 7090500.0 6284.1 6057.8 4330.2 6920.1 8159.2 8688.3 7630.5 8074.8 8949.4 6828.2 True False 7347.874013367457 6659.178349394521 4433.448390374947 6532.389232266909 6560.463331307279 8232.670253121983 6907.68379996402 7862.845055957804 9080.2680443986 8066.0986079985405 0.9109576228191812 0.8255761146771895 0.5496397460326894 0.8098573486058344 0.8133378539163609 1.0206508317364564 0.8563847450506237 0.9748015041820608 1.1257323379848572 1.0 12.977655327450373 -6.647641528576011 3.612407115374857 0.9858036631965615 0.7655813373574284 0.5036243004511359 0.10586352252826525 0.2155228110279191 5.409849941844632 0.03848468228969356 0.03814087690400736 2.2509117665055912e-07 6.647641528576011 -0.22022232583913315 RS(ph)NSSGNLHMAGLTASPTPPSSSIITY ddPTM_PC-9_Lapatinib_30min_R1 1 RSNSSGNLHMAGLTASPTPPSSSIITY 27 1 Q9UKI8-5;Q9UKI8;Q9UKI8-2;Q9UKI8-4;Q9UKI8-3 Q9UKI8-5 TLK1 Serine/threonine-protein kinase tousled-like 1 1 RS(0.349)NS(0.325)S(0.325)GNLHMAGLTASPTPPSSSIITY 49.623000000000005 0.0078586 5165500.0 14809.0 14598.0 18632.0 14370.0 18232.0 20775.0 15349.0 16900.0 19605.0 15888.0 True False 14597.820944361998 14564.199227898445 17100.148881599885 15426.817736914747 17159.629605491136 19886.50167889034 16143.69611676621 17685.235696483232 17396.87845019768 18634.21963057073 0.7833878334466585 0.7815835337694993 0.9176745375237451 0.8278757062413272 0.9208665533457367 1.0672033534618834 0.8663467768879013 0.9490730520031747 0.9335984438895898 1.0 14.185666782266367 -5.455701145828075 0.7897456136051667 0.9557196704655591 0.7438976712176527 0.5471354757328406 0.05865518737455782 0.9714195987647244 0.8627743003345838 0.025999409718816098 0.15402355590507374 3.50186060176448e-06 5.455701145828075 -0.21182199924790635 RS(ph)NSTTQVSQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSNSTTQVSQPR 12 1 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 RS(0.976)NS(0.022)T(0.001)T(0.001)QVSQPR 135.04 8.6971e-05 1725800.0 5311.3 4384.2 3468.5 4992.2 6159.1 5028.6 5124.9 5332.6 5157.4 5110.9 True False 6210.398187043264 4819.434401831598 3551.202194359499 4712.503218930776 4952.268568469296 4764.891363655632 4639.432370937108 5192.624900356737 5232.8172181577875 6037.46571213786 1.0286432226948696 0.7982545378506244 0.5881941800878605 0.780543268255197 0.8202561810849115 0.7892204429544312 0.7684403675551957 0.8600669797457177 0.8667241302319302 1.0 12.559727375307121 -8.597142753664745 1.0301247482757798 0.9985953000658442 0.7877481490749948 0.26488299192649956 0.10075080025333501 0.8651300477115412 1.9808149553306642 0.09970404508960738 0.03258657701364071 2.5284667465960193e-09 8.597142753664745 -0.21084715099084939 RS(ph)NSTTQVSQPR ddPTM_PC-9_Lapatinib_30min_R1 1 RSNSTTQVSQPR 12 1 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 RS(0.95)NS(0.049)TTQVSQPR 122.46 0.00058736 1354400.0 3769.7 2908.0 3352.6 2413.5 4130.1 2974.3 2382.2 3558.5 3309.8 2941.9 True False 3715.943386721685 2901.266704666987 3076.9621694102493 2590.9968411999803 3887.175638089016 2847.09612243194 2505.538659805879 3723.8409009429333 2937.0154702608656 3450.4034951646536 1.0769590837503948 0.8408485293771528 0.8917687956560039 0.750925752547772 1.1265858162781393 0.8251487475078843 0.7261581618837059 1.0792479506125794 0.8512092786761772 1.0 11.752549367258615 -9.47273698051632 0.807435420295554 1.0017027647914234 0.9019448306378639 0.036954079695436626 0.13381239511739737 19.445514688347142 13.369519739227304 0.2506424003833089 0.04374873673270105 3.3671543083351135e-10 9.47273698051632 -0.09975793415355949 RS(ph)NTLDIMDGR ddPTM_PC-9_AZD4547_30min_R2 1 RSNTLDIMDGR 11 1 H0Y9X0;A0A286YEZ9;A0A2C9F2R7;O94915 H0Y9X0 FRYL Protein furry homolog-like 1 RS(0.633)NT(0.367)LDIMDGR 69.045 0.016364 3328700.0 6955.5 5371.9 9635.4 17589.0 12867.0 8922.3 10594.0 12781.0 7369.7 12700.0 True False 9167.204316612473 7108.26162176999 9507.628300341486 13534.127797341074 11080.63915058699 8364.387170536253 11536.845476702603 10805.990128162015 7759.247296459262 12255.37686557915 0.7480148849897698 0.580011671590001 0.7757924056211539 1.1043420325451978 0.9041451170472312 0.6825075444255608 0.9413701107067024 0.8817346252739131 0.6331300441891865 1.0 13.581127228808656 -5.521229623734303 24.998870652527962 0.8742915478905905 0.6674854341779306 0.2874338387293255 0.13536935969615885 74.53930059737107 1129932.6118656127 0.036874138371997434 0.06507985120227966 3.011413384045682e-06 5.521229623734303 -0.2068061137126599 RS(ph)NTLDIMDGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSNTLDIMDGR 11 1 H0Y9X0;A0A286YEZ9;A0A2C9F2R7;O94915 H0Y9X0 FRYL Protein furry homolog-like 1 RS(0.856)NT(0.144)LDIMDGR 73.219 0.024322999999999997 4922100.0 24555.0 19016.0 25952.0 27992.0 30910.0 26611.0 29152.0 29207.0 27706.0 24146.0 True False 28711.67651664327 20903.782807634165 26570.79410350808 26423.698991288456 24853.40738929161 25215.472314011855 26390.511517797153 28440.347197374493 28111.147835397638 28523.478660369175 1.0065979980392636 0.7328623221780485 0.9315411496573812 0.9263841660379883 0.8713315681170123 0.884025143435485 0.9252206518016476 0.9970855075573167 0.9855441606586214 1.0 14.799862319957464 -7.612000949789045 2.838776479944323 0.9949798216404536 0.887574434532315 0.32889979461183494 0.06484416204100588 0.30156858188676916 4.884388781482312 0.03446673824089019 0.01784572137373898 2.4434252089902644e-08 7.612000949789045 -0.10740538710813863 RS(ph)PASIDR ddPTM_PC-9_AZD4547_30min_R2 1 RSPASIDR 8 1 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 RS(1)PASIDR 77.288 0.01089 15595000.0 18029.0 20368.0 24348.0 39282.0 29835.0 24620.0 18052.0 29036.0 24199.0 24827.0 True False 23761.846973503907 26951.557682051247 24025.12961129942 30226.141800850102 25692.92523958675 23080.50750799709 19658.593028642183 24549.153380902302 25478.10973676237 23957.814286750683 0.9918203175422746 1.1249589532445865 1.002809743983447 1.26164020803709 1.0724235914039801 0.9633811846000172 0.8205503554434811 1.0246825143176206 1.0634571848589898 1.0 14.5482086740909 -6.710251496914248 5.204501382049979 0.9661462836242138 1.098999408976707 0.2873229926421095 0.091298739857523 0.246556048994231 14.315601371081097 0.031623096114641515 0.03098840192850811 1.948715785186046e-07 6.710251496914248 0.13285312535249316 RS(ph)PASIDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSPASIDR 8 1 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 RS(1)PASIDR;RS(1)PASIDR 68.355 0.020087999999999998 16452900.0 25183.8 26967.4 29406.1 29298.8 40917.0 32844.5 28350.7 31842.7 31783.0 21377.7 True False 29446.91993727717 29644.54525066226 30107.25294725529 27657.283223991213 32899.607575142145 31122.076600562246 25665.11645470677 31006.862865129508 32247.766247471416 25253.3077842199 1.1660618952926927 1.1738876151973374 1.192210272195252 1.0951944775041902 1.3027840889699291 1.2323960435792722 1.0163071180221466 1.2278337210345507 1.2769719722666255 1.0 14.624184750041222 -10.747166855115834 4.8030114313174 0.9999652056902648 1.1850457337851876 0.33140524671010774 0.07966668459523606 2.99203533764042e-05 4.832098431677586e-06 0.0777517269539928 0.018854021448764673 1.789918038801125e-11 10.747166855115834 0.1850805280949228 RS(ph)PASIDR ddPTM_PC-9_Lapatinib_30min_R1 1 RSPASIDR 8 1 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 RS(1)PASIDR 63.693999999999996 0.026136000000000003 14347000.0 15102.0 13346.0 11027.0 17448.0 15200.0 13981.0 11991.0 12127.0 13941.0 10806.0 True False 14886.64271063239 13315.098156975795 10120.402625450937 18731.184124821735 14305.965884349793 13383.065221302824 12611.835307586396 12690.464691790072 12370.817774761834 12673.802701910086 1.174599531077504 1.0506000819287693 0.7985292862359044 1.4779450623764825 1.1287824357715244 1.0559628815498165 0.995110591841993 1.0013146796010541 0.9760936055046375 1.0 13.629561841365426 -7.010751348719514 3.254559532029315 0.994275781176802 1.1222434106341497 0.1404959168536254 0.1548445475646362 0.5761049154907667 12.64188520435565 0.06354321754700873 0.05129298857892226 9.755480188307771e-08 7.010751348719514 0.12796762945734763 RS(ph)PDIT(ph)KS(ph)PLT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 RSPDITKSPLTK 12 2 P24046-2;P24046 P24046-2 GABRR1 Gamma-aminobutyric acid receptor subunit rho-1 4 RS(1)PDIT(1)KS(1)PLT(1)K 72.615 0.018879 3330500.0 25757.0 23506.0 26701.0 21108.0 26714.0 25135.0 22042.0 22640.0 25652.0 19188.0 True False 25389.700456744693 23451.573301204324 24505.746848840638 22660.352734223816 25142.735041744767 24060.03464254675 23183.226907665685 23691.93705138345 22762.801632464707 22504.62023359714 1.1281994627414516 1.0420781625185338 1.0889207013702908 1.0069200234889626 1.1172254755140985 1.06911533688658 1.0301541046693805 1.052758802657499 1.01147237305885 1.0 14.457933598939482 -1.522878747588081 0.04613644152802828 0.8568228918045863 1.405409162667187 0.3845540128824272 0.03383356621041468 644.211847276605 2.260094640242107 6.71911612135809 25.991172366106962 0.029999999840586735 1.522878747588081 0.5485862708626007 RS(ph)PGPGPSQSPR ddPTM_PC-9_AZD4547_30min_R2 2 RSPGPGPSQSPR 12 1 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 RS(0.999)PGPGPSQSPR;RS(0.999)PGPGPSQS(0.001)PR 106.16 0.00078154 3555100.0 11713.8 13972.5 17867.0 27447.0 23513.3 18415.7 16760.7 23750.2 19681.9 22004.7 True False 15438.544737824059 18488.837377870248 17630.071905909594 21119.518201922812 20248.884164101746 17264.1633677913 18252.36983022175 20080.15231530189 20722.245052604783 21234.322150709417 0.7270561606935154 0.8707053253994527 0.8302629950125623 0.9945934723994583 0.9535922088958819 0.8130310562899001 0.8595692247991988 0.9456460240540823 0.9758844622178097 1.0 14.374110434765552 -3.88991245499925 0.9197286984249122 0.9224981819968057 1.9476827006679617e-12 0.489791827611022 0.06161265422199412 8.792683167361732 1.7424355402298577 0.02160973398557299 11.987580831660225 0.00012885092629731504 3.88991245499925 -0.922498181994858 RS(ph)PGPGPSQSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSPGPGPSQSPR 12 1 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 RS(0.987)PGPGPS(0.001)QS(0.012)PR 82.494 0.0055247 2997800.0 6223.4 6996.2 10462.0 7598.2 11355.0 11885.0 11944.0 10769.0 10416.0 9182.4 True False 7276.898702247104 7690.736499724973 10711.453757355943 7172.497487696769 9130.069262549534 11261.729677653255 10812.577852928414 10486.325160698676 10568.314294863982 10847.096432161594 0.670861437229518 0.709013379554917 0.9874950245299312 0.661236629779592 0.841706286991136 1.038225275130981 0.9968177125142142 0.9667402909415249 0.9742989159319148 1.0 13.405021291018704 -6.608472208166626 4.730577423404277 0.992117705833814 0.7679376494719723 0.6252472795645034 0.08725027422089297 0.14872111732131513 5.928040526512507 0.02960716315852792 0.02966006814312016 2.463359471104873e-07 6.608472208166626 -0.22418005636184168 RS(ph)PILLPK ddPTM_PC-9_AZD4547_30min_R2 2 RSPILLPK 8 1 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 RS(1)PILLPK;RS(1)PILLPK 89.561 0.004645300000000001 22505000.0 31284.0 32587.0 41141.0 62148.0 47921.0 45248.0 38426.0 50062.0 39467.0 45524.0 True False 41231.6612523765 43120.11047648293 40595.44345894815 47820.738777028455 41267.99632667126 42418.63540706145 41845.839558974345 42326.06821031584 41553.14504652261 43930.21861642717 0.9385717292323791 0.9815592053611746 0.924089265601059 1.0885613658008628 0.9393988381209556 0.9655912659446569 0.9525524997803357 0.9634841242171401 0.9458897851007806 1.0 15.422926058494136 -4.751273238721931 23.6919270358838 0.9724080120517795 0.9385715926759312 0.054083011857742114 0.04357124380786681 759.461648513718 1769663.5805388507 0.010542918415985541 0.13370498636681347 1.7730735910544106e-05 4.751273238721931 -0.03383641937584836 RS(ph)PILLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSPILLPK 8 1 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 RS(1)PILLPK;RS(1)PILLPK 94.363 0.0030974 17782100.0 38391.0 35303.0 37439.0 43544.0 47816.0 33198.0 36351.0 44621.0 35634.0 24753.0 True False 44889.8380431868 38807.648530601014 38331.687748198194 41104.37085155274 38446.798050028025 31457.038438261072 32907.57012155065 43449.74602985749 36155.07983709517 29240.5229553598 1.535192722500829 1.3271872254079353 1.3109097879924196 1.405733095618876 1.3148464584139974 1.0758028673524453 1.1254097668427192 1.485942850481514 1.2364717242674323 1.0 14.835681493109208 -1.5228787452949544 0.029908781913453666 2.0734368307454688e-14 3.145727989980267 0.43419357625355415 0.12442042689701192 1569.1003906913852 3.6122085179384618 121.40064097750148 293.0247112216307 0.029999999998990307 1.5228787452949544 3.145727989980246 RS(ph)PILLPK ddPTM_PC-9_Lapatinib_30min_R1 2 RSPILLPK 8 1 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 RS(1)PILLPK;RS(1)PILLPK 94.82 0.0030331 15603300.0 21172.6 38193.0 61056.0 52024.0 58868.0 52433.0 46102.0 48565.0 57705.0 48230.0 True False 20870.67484142068 38104.56645507094 56036.211362975635 55850.01850697651 55405.499978941014 50190.562817292775 48488.935981181545 50821.50719524902 51205.655239411186 56566.49123756464 0.3689582716695162 0.6736243599597085 0.990625547687553 0.9873339725531299 0.9794756359600287 0.8872843572090301 0.857202469524591 0.8984383878754619 0.905229476305339 1.0 15.787660064387252 -4.935287864831415 2.593319170151159 0.9325900359477132 0.3367628917617664 0.9258834103899817 0.05071454611835504 0.09554555042196679 1.066267821254792 0.015001417524096006 0.10857320991696108 1.16067902214181e-05 4.935287864831415 -0.5958271441859468 down RS(ph)PLGQK ddPTM_PC-9_Lapatinib_30min_R1 1 RSPLGQK 7 1 A0A2R8Y6S3;C9J167;P54278;P54278-3;Q68D20 A0A2R8Y6S3;Q68D20 PMS2;PMS2CL Mismatch repair endonuclease PMS2;Protein PMS2CL 1 RS(1)PLGQK 72.643 0.017567 23208000.0 51832.0 68866.0 43009.0 56727.0 69230.0 41778.0 84038.0 81395.0 72665.0 59843.0 True False 51092.86617517534 68706.54500811458 39472.9660395411 60898.89281572458 65158.02751141676 39991.25232927465 88389.07643890793 85176.90884705649 64480.70250362731 70186.7828142148 0.727955665248523 0.9789100205658603 0.5623988514194542 0.8676689595094368 0.9283518192291387 0.5697832373244965 1.2593407603946571 1.2135747705165616 0.9187014978918245 1.0 16.09891175532574 -7.268913710654556 24.99966779093245 1.11570215540551 0.7837516034121349 0.5057679049266854 0.156951666801204 478.99895879227125 1602118.440444926 0.063193406899154 0.04355108222741147 5.3837674118991953e-08 7.268913710654556 -0.3319505519933751 RS(ph)PPADAIPK ddPTM_PC-9_AZD4547_30min_R2 2 RSPPADAIPK 10 1 P18754-2;M0R1Q8;C9JRH2;C9J3R0;C9JMJ4;C9JQZ4;C9JW69;P18754 P18754-2 RCC1 Regulator of chromosome condensation 1 RS(1)PPADAIPK;RS(1)PPADAIPK 87.184 0.004946 6136200.0 71084.0 73465.0 89695.0 137073.0 126256.0 104945.0 80796.0 124350.0 79540.0 90544.0 True False 93687.23336094918 97211.12456362417 88505.58569432813 105472.937606739 108727.53373719666 98382.77255998194 87986.68747740808 105134.56477872995 83744.32201587169 87374.08211944858 1.0722542782523303 1.1125853594745343 1.01295010542523 1.2071421530076571 1.2443911409398947 1.125994919471468 1.007011293773845 1.2032694619326716 0.9584572448084242 1.0 16.41491777434453 -8.277148255401018 24.852201514968783 0.9792285844780987 1.122229037721548 0.3662004411546711 0.07575351306057347 978.7994424927515 1548491.0735332405 0.07465755342919721 0.019557896629149484 5.282648868495731e-09 8.277148255401018 0.14300045324344934 RS(ph)PPADAIPK ddPTM_PC-9_Lapatinib_30min_R1 2 RSPPADAIPK 10 1 P18754-2;M0R1Q8;C9JRH2;C9J3R0;C9JMJ4;C9JQZ4;C9JW69;P18754 P18754-2 RCC1 Regulator of chromosome condensation 1 RS(1)PPADAIPK;RS(1)PPADAIPK 82.925 0.0065313 5073200.0 80651.0 85568.0 98945.0 88093.0 91671.0 87591.0 88648.0 90295.0 100701.0 69879.0 True False 79500.90195041808 85369.87255328229 90810.12403874514 94571.65308963342 86279.09201212032 83844.93711459378 93237.75968200466 94490.4353381038 89358.99295145905 81957.49204208543 0.9700260460580481 1.0416359801425426 1.108014920614138 1.1539110181784304 1.0527297732319059 1.0230295611234557 1.137635588386804 1.1529200440831286 1.0903090214811957 1.0 16.32258821707326 -4.917943153854436 2.7393511493898126 1.0952632126733086 0.9633184178734798 0.35063283680527935 0.04997561083847715 0.36906671102857935 4.632443136524247 0.013355314014078107 0.09695954271018814 1.2079719399358141e-05 4.917943153854436 -0.1319447947998288 RS(ph)PPAPGLQPMR ddPTM_PC-9_Lapatinib_30min_R1 2 RSPPAPGLQPMR 12 1 P15408;P15408-3;P15408-2;C9JCN8 P15408 FOSL2 Fos-related antigen 2 1 RS(1)PPAPGLQPMR;RS(1)PPAPGLQPMR 96.70700000000001 0.0019250999999999997 8013900.0 25274.0 27871.0 32078.0 24236.0 26349.0 26239.3 23643.0 19517.699999999997 30117.0 21137.3 True False 24913.588125316033 27806.46641188914 29440.670664660844 26018.396288925916 24799.203624127153 25117.106305795798 24867.118853912532 20424.563594866904 26724.906313930303 24790.85414131816 1.0049507767379953 1.121642128721372 1.187561771645172 1.0495159279551345 1.000336796899429 1.0131601824857612 1.0030763245251508 0.8238749451083215 1.0780147453406503 1.0 14.59752035828411 -6.179179350207587 2.61933843811893 0.9772431419122143 1.1071688776066437 0.33614393026681055 0.07368262842507084 0.3050195582469922 4.0972759051367085 0.023612600230867076 0.03155154870305102 6.619430851992615e-07 6.179179350207587 0.12992573569442945 RS(ph)PPEEPPDFCCPK ddPTM_PC-9_Lapatinib_30min_R1 1 RSPPEEPPDFCCPK 14 1 A0A087X0G7;A0A087WUW6;A0A087X1B1;Q9Y6K9-3;Q9Y6K9;Q9Y6K9-2 A0A087X0G7 IKBKG NF-kappa-B essential modulator 1 RS(1)PPEEPPDFCCPK 82.12100000000001 0.0044085 7216400.0 20765.0 28988.0 36704.0 32509.0 38837.0 34609.0 31726.0 35968.0 35363.0 25394.0 True False 20468.887292165386 28920.880067017402 33686.33880153723 34899.8203068449 36552.68401647979 33128.853747519446 33368.61704348977 37639.2045876396 31380.046551101274 29783.31906462192 0.6872601152260203 0.9710428849204733 1.131047172024273 1.171790834699166 1.2272871246206691 1.1123291422167758 1.1203793966377187 1.2637679670950202 1.05361146899091 1.0 14.862216916923124 -4.8006788293462765 1.826753168618377 1.1496586943800013 0.5471184356586332 0.7778690104156625 0.07331915705728086 0.3377730351859809 1.2098448670731428 0.01900421889031678 0.3505699697725746 1.5824178406780197e-05 4.8006788293462765 -0.6025402587213682 RS(ph)PSIVASNQGR ddPTM_PC-9_Lapatinib_30min_R1 1 RSPSIVASNQGR 12 1 Q8TED9;Q8TED9-4 Q8TED9 AFAP1L1 Actin filament-associated protein 1-like 1 1 RS(0.669)PS(0.331)IVASNQGR 98.25299999999999 0.0054591 2824200.0 13001.0 7456.9 10960.0 12931.0 10919.0 9252.2 9043.3 8935.2 17189.0 14483.0 True False 12815.603355908595 7439.634006200566 10058.911106823462 13881.988876551468 10276.76588757996 8856.504973931615 9511.517824793269 9350.362011551306 15252.993811805547 16986.36725261556 0.7544640455089212 0.4379767548623447 0.592175534487787 0.8172429496020651 0.6050008065142678 0.5213889963769558 0.5599500872282557 0.550462725342968 0.8979550238710924 1.0 14.052089726655607 -8.377701055461289 3.9894337703428984 0.9929788668169566 0.6018289231965667 0.6388829307153043 0.10445573098078717 0.1415013416142725 3.6411856591311635 0.10217377687410208 0.02701492385461859 4.1908193891334636e-09 8.377701055461289 -0.3911499436203899 RS(ph)PSPGNSPSGR ddPTM_PC-9_AZD4547_30min_R2 1 RSPSPGNSPSGR 12 1 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 RS(0.528)PS(0.472)PGNSPSGR 82.48299999999999 0.0055303 1945800.0 837.5 1624.2 862.39 2737.2 1248.9 762.26 1234.1 1126.6 800.85 1882.6 True False 1103.8075789178276 2149.190887037886 850.9541451243842 2106.1808293184367 1075.5117925832046 714.5957616996693 1343.932509231516 952.5098566925385 843.1812960323215 1816.6907470188428 0.607592448373041 1.183025173967925 0.46840891688405684 1.159350226655055 0.5920169926268961 0.3933502512039037 0.7397695570569098 0.524310402447742 0.464130341069864 1.0 10.827097136972379 -6.441586365454971 24.999404931107467 0.5896654791860152 0.8536215842753698 0.16252373545396537 0.25697695367955864 154.39563032894085 47478.912937718815 0.07377570138043849 0.08365376091256203 3.6175424375194705e-07 6.441586365454971 0.26395610508935463 RS(ph)PT(ph)SSPTPQR ddPTM_PC-9_AZD4547_30min_R2 1 RSPTSSPTPQR 11 1 A0A0D9SFE4;A0A0D9SFB1;A0A0U1RQP1;Q05193-5;Q05193-3;Q05193-2;Q05193 A0A0D9SFE4 DNM1 Dynamin-1 2 RS(0.8)PT(0.657)S(0.517)S(0.023)PT(0.003)PQR 92.781 0.029766 8621000.0 10221.0 9643.4 13321.0 18549.0 13818.0 14498.0 13655.0 16156.0 12643.0 14141.0 True False 13471.065389992975 12760.440463034814 13144.354836213217 14272.814629193219 11899.609216041888 13591.437768112997 14870.268546759871 13659.4614279466 13311.283168803933 13645.927894185406 0.9871857373460884 0.9351097676891652 0.9632437558030837 1.0459394729232692 0.8720263882613924 0.9960068581268389 1.089722052034011 1.0009917635404597 0.9754765870099558 1.0 13.736182877703124 -6.993779729938112 24.9999230896425 1.0203779996459046 0.9611420823624096 0.22427251646638258 0.04910030372889707 234.45624352056313 942298.5087999153 0.01724056130179869 0.015168574168349661 1.0144257624536326e-07 6.993779729938112 -0.05923591728349498 RS(ph)PTEDFR ddPTM_PC-9_AZD4547_30min_R2 1 RSPTEDFR 8 1 Q8IXT5 Q8IXT5 RBM12B RNA-binding protein 12B 1 RS(0.997)PT(0.003)EDFR 76.282 0.011542 8840200.0 20319.0 19838.0 20793.0 18631.0 22451.0 25944.0 19791.0 27163.0 16510.0 19360.0 True False 26780.019338544877 26250.245546766157 20517.271234095148 14335.910796080601 19334.066182469003 24321.71757869522 21552.36065975281 22965.582493644062 17382.684894166967 18682.212292725373 1.4334501138803937 1.405092990886721 1.0982249271455031 0.7673561659323843 1.0348916862483921 1.3018649610445656 1.1536300049510215 1.2292753199569721 0.9304403901317176 1.0 14.189377684423722 -5.26466075556267 5.328688209843303 1.0715538630779198 1.424110546874208 0.49748889229038884 0.142783573858903 0.14491523441246326 14.708942408382116 0.04049307639905292 0.09790643510054753 5.436748513962127e-06 5.26466075556267 0.35255668379628813 RS(ph)PTEDFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSPTEDFR 8 1 Q8IXT5 Q8IXT5 RBM12B RNA-binding protein 12B 1 RS(0.982)PT(0.018)EDFR 62.107 0.028993 2665300.0 11779.0 13886.0 14810.0 12583.0 14009.0 11049.0 13280.0 12082.0 11077.0 12812.0 True False 13772.952054145424 15264.510310623045 15163.126567237778 11878.015304636418 11264.037014447946 10469.570989347147 12022.022261126032 11764.860301937164 11238.980169374849 15134.714180263802 0.9100239284403426 1.0085760542824458 1.0018772992099862 0.7848192680193304 0.7442517169657981 0.6917587517443728 0.794334278000649 0.7773427473958481 0.7425961293693193 1.0 13.885573809613481 -5.767546530603519 24.347273669897803 0.7755414638724308 0.9770008092459985 0.5092331832710624 0.0812464485683442 70.10658266146653 279494.59669662674 0.02145217145621517 0.03277917839284714 1.7078647284788008e-06 5.767546530603519 0.2014593453735677 RS(ph)PTEDFR ddPTM_PC-9_Lapatinib_30min_R1 1 RSPTEDFR 8 1 Q8IXT5 Q8IXT5 RBM12B RNA-binding protein 12B 1 RS(0.999)PT(0.001)EDFR 58.815 0.034922 2463000.0 10699.0 12572.0 10827.0 10922.0 12899.0 11178.0 12040.0 13487.0 10845.0 10359.0 True False 10546.4302980437 12542.890306421385 9936.84585342862 11725.24031472392 12140.30618040973 10699.942997190685 12663.372287827558 14113.655256714163 9623.521897087161 12149.539347500137 0.8680518657041686 1.032375792009117 0.8178784042107081 0.9650769448420676 0.9992400397392592 0.8806871348083072 1.0422923804459423 1.1616617595973429 0.7920894465078856 1.0 13.568613994312535 -7.271046565183424 24.7891968033596 1.012482710228524 0.9320228050140646 0.09683529861427798 0.10359056396556075 1330.2376631859286 3432366.3035018635 0.041237123669199696 0.02820114231686626 5.3573921231618266e-08 7.271046565183424 -0.08045990521445945 RS(ph)PTGSTTSR ddPTM_PC-9_AZD4547_30min_R2 1 RSPTGSTTSR 10 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 RS(1)PTGSTTSR 95.428 0.0027140999999999997 4490500.0 734.04 588.57 0.0 924.3 348.7 0.0 514.54 551.86 913.49 0.0 True False 967.4494510195135 778.8137423863375 0.0 711.2169152926466 300.2890240001309 0.0 560.3330632039412 466.5827174812218 961.7752164732034 0.0 0.0 RS(ph)PTGSTTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSPTGSTTSR 10 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 RS(0.973)PT(0.008)GS(0.008)T(0.003)T(0.008)SR 80.87100000000001 0.025065 5069300.0 2779.5 5168.9 5106.4 2561.7 11880.0 12087.0 4086.9 8723.9 12338.0 14399.0 True False 3250.0144523726312 5682.034231929967 5228.155942129843 2418.176254143456 9552.199281293566 11453.136442052584 3699.7592454063224 8494.906868736109 12518.419908797228 17009.42471757871 0.191071391674631 0.33405211088989756 0.3073681814016148 0.1421668453986187 0.5615827366237535 0.6733406115855362 0.2175123090190544 0.4994235260618125 0.7359696237027835 1.0 14.054046727421335 -10.452251522115635 0.13464238432016112 1.721682109470261 2.4313783600308224e-20 0.6754025514727486 0.15031238340046477 20.269862676547795 0.5782664445097722 6.657522174076675 1.5486285579167507 3.529786826000507e-11 10.452251522115635 -1.721682109470261 RS(ph)PTGSTTSR ddPTM_PC-9_Lapatinib_30min_R1 1 RSPTGSTTSR 10 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 RS(0.999)PT(0.001)GSTTSR 70.54 0.016278 6492200.0 0.0 0.0 620.76 0.0 788.89 0.0 457.66 702.02 408.02 0.0 True False 0.0 0.0 569.7235090028955 0.0 742.4890412174149 0.0 481.3553954524217 734.6384120500097 362.06449095892145 0.0 0.0 RS(ph)PTSSPTPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSPTSSPTPQR 11 1 A0A0D9SFE4;A0A0D9SFB1;A0A0U1RQP1;Q05193-5;Q05193-3;Q05193-2;Q05193 A0A0D9SFE4 DNM1 Dynamin-1 1 RS(0.989)PT(0.002)S(0.009)S(0.001)PTPQR 93.839 0.0031554 1776700.0 7335.0 8132.8 5854.8 5414.6 11353.0 11315.0 5880.8 7211.8 6693.6 9420.4 True False 8576.670627146343 8940.17063619726 5994.400636452647 5111.2375163700535 9128.46114819241 10721.621481080903 5323.728050695026 7022.497891533725 6791.481236952919 11128.243948154632 0.770711953036273 0.8033765864451403 0.5386654592027238 0.45930315152892 0.8202966425539368 0.9634603205170428 0.4783978564360863 0.6310517566159437 0.6102922679080137 1.0 13.441938330974242 RS(ph)PTSSPTPQR ddPTM_PC-9_Lapatinib_30min_R1 2 RSPTSSPTPQR 11 1 A0A0D9SFE4;A0A0D9SFB1;A0A0U1RQP1;Q05193-5;Q05193-3;Q05193-2;Q05193 A0A0D9SFE4 DNM1 Dynamin-1 1 RS(1)PTSSPTPQR;RS(0.386)PT(0.199)S(0.199)S(0.199)PT(0.018)PQR 105.25 0.0022271 0.0 5556.0 6574.299999999999 7718.9 4674.1 6157.8 7791.7 8099.0 6569.2 6667.2 5596.5 True False 5476.770421154382 6559.077612273787 7084.281837815657 5017.848906340514 5795.610310700602 7458.467154339829 8518.326591288655 6874.42901404365 5916.269727271507 6563.847568132497 0.8343841572043997 0.9992732988069576 1.0792879883758835 0.7644676166311644 0.8829593086284194 1.1362949972437983 1.2977642309436253 1.0473169802752622 0.9013417307243722 1.0 12.68032602027593 -6.759868831121995 24.997691730507952 1.093327199830875 0.9180080981510271 0.2977783158533306 0.12479478523949636 55.582277082643905 884681.6404477265 0.04507338345745367 0.04282504345617994 1.738325771664278e-07 6.759868831121995 -0.17531910167984777 RS(ph)PTVEPSTLPR ddPTM_PC-9_AZD4547_30min_R2 2 RSPTVEPSTLPR 12 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 RS(0.995)PT(0.005)VEPSTLPR;RS(0.99)PT(0.009)VEPSTLPR 95.822 0.0020519 38517000.0 41795.0 61306.0 69526.0 90109.0 82173.0 75886.0 65305.0 92669.0 74494.0 72204.0 True False 55084.940609994745 81121.96559582847 68604.03981251865 69335.7622201722 70764.69735922784 71140.83642371513 71117.01848745174 78349.13537177414 78431.60075748488 69676.15993718714 0.790585196710807 1.1642714763408273 0.9846128126803342 0.995114574090739 1.0156228101982372 1.0210211999032148 1.0206793622318384 1.1244755084437155 1.125659060835022 1.0 16.088377494412775 -7.647246863583475 5.55138086610032 1.0932224565785564 1.004760038368046 0.15017471556071638 0.09109159950440156 0.37258413715924826 16.575144795567354 0.041436377245915125 0.023358518267898983 2.252958211674781e-08 7.647246863583475 -0.08846241821051049 RS(ph)PTVEPSTLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSPTVEPSTLPR 12 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 RS(0.848)PT(0.149)VEPS(0.002)T(0.001)LPR;RS(0.961)PT(0.038)VEPSTLPR 72.66199999999999 0.011231 34692000.0 24969.0 34328.2 37024.0 39723.0 40036.0 35311.0 42968.0 33074.0 37850.0 27870.4 True False 29195.758539770548 37736.07682882975 37906.79257430189 37497.44909370361 32191.233200830742 33459.22899853716 38897.75997861923 32205.842544799692 38403.48464483504 32923.08289803501 0.8867868975147851 1.1461890414606948 1.1513743318540903 1.138941004092348 0.9777709244462052 1.0162848085084446 1.1814738036255046 0.9782146661217401 1.1664607705108663 1.0 15.006811814745836 -10.568813962122166 5.022926030771323 0.9999988036676666 1.0741393330741562 0.04684683720130256 0.09609167055248917 1.243688252019586e-06 2.3627236246404258e-07 0.08988947899952306 0.021801049147412738 2.6988953053612847e-11 10.568813962122166 0.07414052940648963 RS(ph)PTVEPSTLPR ddPTM_PC-9_Lapatinib_30min_R1 2 RSPTVEPSTLPR 12 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 RS(0.999)PT(0.001)VEPSTLPR;RS(1)PTVEPSTLPR 156.6 0.00017368 33451000.0 24421.1 26772.1 27781.0 24697.0 32967.0 28882.0 27753.0 27015.7 31280.0 17342.3 True False 24072.85063571876 26710.110847322932 25496.953417761193 26513.299766776843 31027.945875615755 27646.78418723037 29189.914543528084 28270.94804766166 27756.91700699736 20339.8934478378 1.1835288467687517 1.3131883367934905 1.2535440995867955 1.3035122251142028 1.5254723902653546 1.3592393813729302 1.4351065613193303 1.389926064271834 1.3646540026466074 1.0 14.312024501091045 -6.009022362944687 23.574289743953873 1.3743841713295042 1.2600856493419932 0.06961846189087839 0.1326527756517334 395.61973292369817 1033716.4770912938 0.035429961204898434 0.04952231913351537 9.79439550237788e-07 6.009022362944687 -0.114298521987511 RS(ph)PVPAQIAITVPK ddPTM_PC-9_AZD4547_30min_R2 3 RSPVPAQIAITVPK 14 1 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 RS(1)PVPAQIAITVPK;RS(1)PVPAQIAITVPK;RS(1)PVPAQIAITVPK 169.06 3.0529e-05 130241000.0 339373.0 362062.0 473012.0 567051.0 565938.0 494655.0 449892.0 573631.0 470256.0 470685.0 True False 447286.55460307974 479091.4609916948 466739.5518194495 436326.15280061687 487367.2775009632 463724.1446534659 489931.5164437121 484989.5096790308 495112.7721133491 454206.46141536324 0.9847648428630447 1.0547878590251378 1.0275933776129729 0.9606339624517248 1.0730082438331388 1.0209545306961165 1.0786537798626317 1.0677732504459398 1.0900610497052745 1.0 18.792988704007804 -6.2981112176352605 24.98924402796808 1.0579367095807588 1.0118371994265056 0.3116964790516946 0.03457907833652139 735.258917313716 501024.2423918395 0.010561718139906235 0.01197624381430158 5.033716847978978e-07 6.2981112176352605 -0.046099510154253176 RS(ph)PVPAQIAITVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSPVPAQIAITVPK 14 1 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 RS(1)PVPAQIAITVPK;RS(1)PVPAQIAITVPK 134.4 1.0687000000000001e-05 82553000.0 230540.0 261830.0 309070.0 352930.0 386480.0 313690.0 382550.0 304210.0 293880.0 257690.0 True False 269565.86862744606 287822.7520258132 316439.4009545024 333156.47631449875 310752.01836989314 297239.54418031534 346312.0945778443 296224.80983713764 298177.4390336629 304407.15712708165 0.8855437932916593 0.9455190040280659 1.039526809885083 1.0944436374582844 1.020843337925076 0.9764538619445993 1.1376608153574672 0.9731203846612315 0.9795349158271662 1.0 18.215642753877354 -5.06121450370744 3.0289276670477583 1.0308524318290857 0.8901061445237991 0.4569811271365867 0.05070903638293341 0.23507120483401586 4.032261180017801 0.013504869664368204 0.05693582642989385 8.685313443738176e-06 5.06121450370744 -0.1407462873052866 RS(ph)PVPAQIAITVPK ddPTM_PC-9_Lapatinib_30min_R1 2 RSPVPAQIAITVPK 14 1 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 RS(1)PVPAQIAITVPK;RS(1)PVPAQIAITVPK 153.68 0.00010795 82723000.0 336250.0 376290.0 412040.0 357500.0 368520.0 366270.0 328320.0 355880.0 379970.0 274820.0 True False 331455.0133393025 375418.7236241888 378163.66172039544 383791.7425850389 346844.3781381962 350605.48591707175 345318.8031179023 372415.4840038136 337173.7773385165 322322.27082536876 1.0283341963636194 1.1647309466480744 1.1732470758289024 1.1907081121086223 1.076079469315086 1.087748249661056 1.0713463957474811 1.155413440871372 1.046076575705171 1.0 18.298144349149133 -6.291245430166648 23.91083465776491 1.0812250093565081 1.1435027938072406 0.249918752645086 0.05507355204594115 615.2347129287318 493547.7916355891 0.016921693801690892 0.01919163346913489 5.113927536262001e-07 6.291245430166648 0.06227778445073251 RS(ph)QSTTFNPDDMSEPEFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSQSTTFNPDDMSEPEFK 18 1 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 RS(0.435)QS(0.187)T(0.187)T(0.187)FNPDDMS(0.003)EPEFK 44.963 0.039751 5710800.0 27434.0 26450.0 31274.0 35461.0 45180.0 30407.0 38951.0 39254.0 35217.0 32194.0 True False 32078.03435380131 29075.781198039713 32019.690767305474 33474.235136113144 36327.303327343696 28812.403391535747 35261.279299180715 38223.62409305094 35731.98200098167 38030.51735243624 0.843481408799357 0.7645381452108254 0.841947283298114 0.8801940511589906 0.9552145449584993 0.7576127120366407 0.9271837922268463 1.0050776785081608 0.9395607656305699 1.0 15.214869944516307 -7.207673932866306 0.40610150304669945 1.011914515005628 0.7971465010294349 0.503066906542136 0.059502949605212366 1.063689204435419 0.40749127356222414 0.06774330137696329 0.08105744608234976 6.199063244088104e-08 7.207673932866306 -0.21476801397619305 RS(ph)RS(ph)RSPT(ph)PPSSAGLGS(ph)NSAPPIPDS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 RSRSRSPTPPSSAGLGSNSAPPIPDSR 27 3 J3QK89;Q8IWX8 J3QK89 CHERP Calcium homeostasis endoplasmic reticulum protein 5 RS(0.664)RS(0.664)RS(0.664)PT(0.785)PPS(0.117)S(0.106)AGLGS(0.654)NS(0.654)APPIPDS(0.691)R 40.669000000000004 0.027282 47702000.0 14908.0 9531.0 17779.0 28277.0 21780.0 20310.0 15690.0 25431.0 16520.0 18215.0 True False 19648.433894336682 12611.709361136614 17543.23884340777 21758.174525295006 18756.222950165895 19040.01248933474 17086.379604442493 21501.223296243512 17393.21347375157 17577.298394214497 1.1178301382653828 0.7174998727499393 0.9980622988787664 1.237856582810054 1.0670708620580418 1.083216092844034 0.972070862156292 1.2232382254670353 0.9895271209298285 1.0 14.10142572689191 -5.521952196993906 24.991157543193623 1.088479014578524 0.9026940145586717 0.22048197106184364 0.123576293544224 37.90414237651776 1022363.6511568279 0.031166046200263968 0.05487084584268421 3.006407201128275e-06 5.521952196993906 -0.1857850000198522 RS(ph)SAIGIENIQEVQEK ddPTM_PC-9_AZD4547_30min_R2 2 RSSAIGIENIQEVQEK 16 1 J3KPC5;P47736-3;F2Z357;P47736;A0A0A0MQY8;X6R8W7;P47736-2;P47736-4 J3KPC5;P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 RS(0.882)S(0.118)AIGIENIQEVQEK;RS(0.5)S(0.5)AIGIENIQEVQEK 147.75 1.3840999999999998e-05 78246300.0 79565.0 64801.0 73474.0 98973.0 106895.0 79277.0 95092.0 125008.0 105442.0 92598.0 True False 104865.0149451904 85746.6559973784 72499.68675294117 76156.30396760687 92054.47439201015 74319.79665765585 103555.00378238648 105690.88599806592 111015.44885589048 89356.17220463767 1.1735620758802805 0.9596052950993359 0.8113562271547076 0.8522780473765 1.0301971550571012 0.831725384201256 1.158901519922223 1.1828045381803012 1.2423926195232509 1.0 16.44727976524012 -7.280622588991992 23.95384220288529 1.1612584421801595 0.937709519012601 0.4249536101899174 0.11498390344982469 446.23066180214926 557199.6403297477 0.04856810054101089 0.032812472434276124 5.240556541084529e-08 7.280622588991992 -0.22354892316755848 RS(ph)SAIGIENIQEVQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSSAIGIENIQEVQEK 16 1 J3KPC5;P47736-3;F2Z357;P47736;A0A0A0MQY8;X6R8W7;P47736-2;P47736-4 J3KPC5;P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 RS(0.858)S(0.142)AIGIENIQEVQEK;RS(0.842)S(0.158)AIGIENIQEVQEK 115.38 8.1213e-05 68615200.0 189012.0 202940.0 151874.0 218025.0 234984.0 141571.0 133085.0 176108.0 119041.0 124629.0 True False 221007.99844283372 223086.54201626414 155495.2521453527 205809.76609658723 188940.57204675782 134146.767538498 120478.22534803918 171485.35160185004 120781.7494215535 147223.251137379 1.5011759130125695 1.5152942235197246 1.0561867839764985 1.3979433581760747 1.2833609541094224 0.9111792227256353 0.8183369435009751 1.164798021216304 0.8203986020445097 1.0 17.167646010312765 -6.697267252092142 4.753726629083858 0.9449327824867976 1.3531178245514524 0.651790816139636 0.1496463514087299 0.13771943796870656 6.086820777457011 0.051725157545696336 0.050757297654372126 2.0078568561162423e-07 6.697267252092142 0.4081850420646548 RS(ph)SAIGIENIQEVQEK ddPTM_PC-9_Lapatinib_30min_R1 3 RSSAIGIENIQEVQEK 16 1 J3KPC5;P47736-3;F2Z357;P47736;A0A0A0MQY8;X6R8W7;P47736-2;P47736-4 J3KPC5;P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 RS(0.53)S(0.47)AIGIENIQEVQEK;RS(0.851)S(0.149)AIGIENIQEVQEK;RS(0.5)S(0.5)AIGIENIQEVQEK 127.58 1.1025e-05 64814900.0 235582.0 242469.0 294564.0 234646.0 201440.0 185805.0 170772.0 182828.0 229557.0 255268.0 True False 232222.5574795524 241907.5779277508 270346.0849699215 251902.6495961095 189591.69524627787 177858.55328261002 179613.73856618645 191322.85632642783 203701.8733176242 299390.733676771 0.775650450592319 0.8079995494747666 0.9029874827782521 0.8413842556265261 0.6332583941992185 0.5940683303666644 0.599930854106198 0.6390406742948308 0.6803880361158584 1.0 18.191670044245136 -6.256370987039146 24.48857460077464 0.663654934344133 0.8353608872738383 0.24495281162839033 0.11522347236087199 361.31756684408407 1745748.8851775068 0.03266299293939424 0.040846059454023274 5.541521377640768e-07 6.256370987039146 0.17170595292970525 RS(ph)SDGS(ph)LSHEEDLAK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSDGSLSHEEDLAK 15 1 A0A2R8Y7R9;Q13136-2;Q13136;E9PJZ7;H0YEF9 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 2 RS(0.65)S(0.353)DGS(0.831)LS(0.166)HEEDLAK 75.319 0.011389 9465400.0 61910.0 58321.0 58438.0 50021.0 57414.0 52351.0 42691.0 52046.0 55788.0 42912.0 True False 61027.15204709644 58185.961307731595 53633.453217203416 53699.711205164414 54037.02140026704 50112.06976614147 44901.33109133272 54464.24716326432 49504.56796631611 50329.28202335419 1.2125575727223394 1.1561055307868624 1.065651069536736 1.0669675593672536 1.0736696258689395 0.9956841773122864 0.8921512345536193 1.0821582381801391 0.9836136335770618 1.0 15.619110396642467 -4.5933407601141365 0.54054568308163 0.9910837668646819 1.4147608939661964 0.692969016787545 0.04782741664382211 2.955977187450062 0.5690060314642268 0.028144844983945025 0.8259798523568416 2.550699164355477e-05 4.5933407601141365 0.4236771271015145 RS(ph)SDGSLSHEEDLAK ddPTM_PC-9_AZD4547_30min_R2 1 RSSDGSLSHEEDLAK 15 1 A0A2R8Y7R9;Q13136-2;Q13136;E9PJZ7;H0YEF9 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 RS(0.496)S(0.496)DGS(0.009)LSHEEDLAK 81.854 0.0038485 11118000.0 16612.0 20739.0 34364.0 44704.0 35296.0 33037.0 23920.0 30615.0 26361.0 29085.0 True False 21894.27044893486 27442.47617675083 33908.31090696126 34398.18346991505 30395.759653308338 30971.191167412686 26048.8336608199 25884.15521271265 27754.38864295187 28066.74300278499 0.7800787731858431 0.9777577745315081 1.2081313069919308 1.22558515131242 1.0829813651798588 1.1034836198963127 0.9281031881125338 0.9222358009315235 0.9888710150728167 1.0 14.776574035977076 -7.262662104084884 24.97100211153226 0.9533221478115019 1.0740231636115865 0.14743927891393172 0.11942337816835523 211.10988142431876 4311294.332547287 0.05250483031664971 0.037684763049646526 5.461826445425523e-08 7.262662104084884 0.12070101580008452 RS(ph)SDGSLSHEEDLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSDGSLSHEEDLAK 15 1 A0A2R8Y7R9;Q13136-2;Q13136;E9PJZ7;H0YEF9 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 RS(0.577)S(0.417)DGS(0.005)LSHEEDLAK 77.562 0.0058655 8463600.0 17103.0 21941.0 35067.0 40996.0 44104.0 34919.0 36270.0 40082.0 30312.0 26195.0 True False 19998.20010035226 24119.15747698259 35903.13027233807 38699.12703082528 35462.13780321308 33087.786168613704 32834.24302793983 39029.88997038945 30755.25565533001 30943.946140494096 0.6462718106331651 0.7794467249740846 1.1602634683155117 1.2506202943580793 1.1460121356922335 1.0692814038127516 1.0610877771976226 1.261309394515584 0.993902184152358 1.0 14.91736956839522 -5.158989874714503 3.713398772093331 1.129489035684621 0.6735334626504113 0.7711017287600962 0.0891063553955881 0.10063264865676151 2.4873136263029507 0.02291111478172471 0.07183236503625239 6.934419729641056e-06 5.158989874714503 -0.45595557303420975 RS(ph)SDGSLSHEEDLAK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSDGSLSHEEDLAK 15 1 A0A2R8Y7R9;Q13136-2;Q13136;E9PJZ7;H0YEF9 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 RS(0.5)S(0.5)DGS(0.001)LSHEEDLAK 124.73 1.303e-05 15034000.0 66250.0 44807.0 83990.0 58986.0 69852.0 78144.0 70857.0 65610.0 81683.0 58769.0 True False 65305.2628512379 44703.25214443387 77084.66641077596 63324.02721152771 65743.44269431596 74801.96328256116 74525.62875403637 68658.4801210808 72483.0003798774 68927.14334522985 0.947453494832198 0.6485580277211298 1.1183499368991425 0.9187095843267686 0.9538106398089364 1.085232314182913 1.0812232327802391 0.9961022144381724 1.0515886320261034 1.0 16.07278460425073 -5.269987681356611 24.99841880229688 1.0232188448854882 0.7980057553234796 0.5126966531184871 0.08874026273331523 419.55822402872633 1226946.6493282903 0.02218749237273962 0.0473878622603484 5.370470293453151e-06 5.269987681356611 -0.22521308956200858 RS(ph)SDPALIGLSTSVSDSNFSSEEPSR ddPTM_PC-9_AZD4547_30min_R2 4 RSSDPALIGLSTSVSDSNFSSEEPSR 26 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 RS(0.5)S(0.5)DPALIGLSTSVSDSNFSSEEPSR;RS(0.5)S(0.5)DPALIGLSTSVSDSNFSSEEPSR;RS(0.5)S(0.5)DPALIGLSTSVSDSNFSSEEPSR;RS(0.5)S(0.5)DPALIGLSTSVSDSNFSSEEPSR 171.32 5.3085e-14 145784000.0 125728.0 124040.0 155847.0 226360.0 193424.0 159536.0 152612.0 196782.0 148093.0 161896.0 True False 165706.88869514142 164133.50426559502 153780.36695137917 174176.1992271377 166570.4163412713 149560.18870007378 166194.17235138203 166373.86350050723 155920.8936421485 156228.07031730725 1.0606729530652346 1.0506018792412364 0.9843324995248506 1.1148841490096937 1.0662003057642473 0.9573195674523108 1.0637920062241895 1.0649421910069896 0.9980337933219372 1.0 17.25329416779642 RS(ph)SDPALIGLSTSVSDSNFSSEEPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RSSDPALIGLSTSVSDSNFSSEEPSR 26 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 RS(0.616)S(0.384)DPALIGLSTSVSDSNFSSEEPSR;RS(0.5)S(0.5)DPALIGLSTSVSDSNFSSEEPSR;RS(0.5)S(0.5)DPALIGLSTSVSDSNFSSEEPSR;RS(0.5)S(0.5)DPALIGLSTSVSDSNFSSEEPSR 149.12 5.7286e-12 80489900.0 119748.90000000001 157961.9 150023.2 141337.6 180661.4 167185.7 163157.0 145039.4 130646.0 101066.7 True False 140020.02362141572 173643.31349817157 153600.3220541544 133418.91249468154 145262.0955587109 158418.1875783957 147701.58780561268 141232.26943194703 132556.4505920507 119389.29266644316 1.1728021876518853 1.4544295356812817 1.2865502309599242 1.117511541570442 1.2167095751589105 1.3269044823055764 1.2371426658692928 1.1829559106822927 1.110287594737618 1.0 16.865313929886284 -8.346147371637654 1.176972993619784 1.0015301230794404 1.2658846462353341 0.4922517351768675 0.0857340066664141 0.40261370858010814 1.166663051106782 0.08492149256288978 0.027313787283776408 4.506637522757793e-09 8.346147371637654 0.2643545231558937 RS(ph)SDPALIGLSTSVSDSNFSSEEPSR ddPTM_PC-9_Lapatinib_30min_R1 4 RSSDPALIGLSTSVSDSNFSSEEPSR 26 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 RS(0.5)S(0.5)DPALIGLSTSVSDSNFSSEEPSR;RS(0.5)S(0.5)DPALIGLSTSVSDSNFSSEEPSR;RS(0.5)S(0.5)DPALIGLSTSVSDSNFSSEEPSR;RS(0.5)S(0.5)DPALIGLSTSVSDSNFSSEEPSR 139.12 2.4649e-10 153696000.0 180377.0 142755.0 172660.0 140378.0 157407.0 150571.0 151624.0 141097.0 152296.0 133085.0 True False 177804.79090290974 142424.4595683414 158464.5612868739 150701.86640728026 148148.6297340688 144131.42932814438 159474.34881807005 147652.8817199231 135142.82073202278 156088.56492538415 1.1391275907232967 0.9124592800018716 1.0152221039550564 0.9654894737440957 0.9491318586014873 0.9233951852721838 1.0216914281600604 0.9459557898460172 0.8658085926834282 1.0 17.252005323541717 -4.752810269386368 24.997052163623945 0.9568233423012807 1.1391279349732721 0.5897909759372835 0.045939285163347804 233.4785164708442 676296.5936269448 0.011185007753005181 0.1284185384082061 1.7668095197418038e-05 4.752810269386368 0.1823045926719914 RS(ph)SDPALIGLSTSVSDSNFSSEEPSRK ddPTM_PC-9_AZD4547_30min_R2 2 RSSDPALIGLSTSVSDSNFSSEEPSRK 27 2 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 RS(0.5)S(0.5)DPALIGLSTSVSDSNFSSEEPSRK;RS(0.5)S(0.5)DPALIGLSTSVSDSNFSSEEPSRK 95.926 9.2126e-10 16068200.0 40396.0 36889.0 59814.0 85207.0 66568.0 66926.0 49057.0 67948.0 57196.0 57859.0 True False 53241.08771100249 48812.64784628773 59020.82727822669 65563.84258502704 57326.182247320605 62741.106640138714 53422.97796399841 57448.197889707546 60219.26379205172 55833.37402090898 0.9535710252986733 0.8742557422377507 1.0570886734540534 1.1742769219082858 1.0267368442726135 1.1237204940658407 0.9568287587992103 1.028922197469095 1.0785531923881275 1.0 15.768840120624732 -5.272084908821172 24.001179492146647 1.0588880986803408 0.9139133859533646 0.46556279201906514 0.0607196913964656 308.5561852359269 695666.0299679975 0.016003432888400324 0.033915159846566525 5.3445985704946835e-06 5.272084908821172 -0.14497471272697626 RS(ph)SDPALIGLSTSVSDSNFSSEEPSRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSDPALIGLSTSVSDSNFSSEEPSRK 27 2 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 RS(0.5)S(0.5)DPALIGLSTSVSDSNFSSEEPSRK 72.805 3.4409e-05 4987100.0 18363.0 18921.0 24068.0 25059.0 28339.0 20521.0 21679.0 25615.0 22502.0 19998.0 True False 21471.4932142179 20799.351835467296 24641.87239839829 23655.025472374142 22786.176383213675 19444.84263484413 19625.40817763188 24942.633391335912 22831.049180398375 23623.479095919098 0.9089047860832256 0.8804525256849376 1.0431093700612082 1.0013353823256497 0.964556333582124 0.8231151117027121 0.830758589704178 1.0558408137116728 0.9664558335246389 1.0 14.527933829670202 -7.784192899915058 24.99821374102855 1.0083612171328613 0.9257409173903112 0.24576850173946363 0.06853103318010507 411.89617504662374 452524.1598982548 0.04154177268361169 0.019977602542487986 1.643641507325849e-08 7.784192899915058 -0.08262029974255014 RS(ph)SDPLGDTASNLGSAVDELMR ddPTM_PC-9_AZD4547_30min_R2 2 RSSDPLGDTASNLGSAVDELMR 22 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 RS(0.464)S(0.464)DPLGDT(0.063)AS(0.009)NLGSAVDELMR;RS(0.499)S(0.499)DPLGDT(0.002)ASNLGSAVDELMR 68.676 0.00082521 28795000.0 20639.8 16538.7 20730.8 28282.0 25674.7 26364.0 21513.0 28111.0 23618.3 21413.9 True False 27202.827065490364 21884.511343094116 20455.896046735903 21762.021852544214 22110.211082581478 24715.454912300374 23427.615323796774 23767.09087651689 24866.715120284913 20664.205878883873 1.3164225726810102 1.0590540701811937 0.9899192916791041 1.0531264535445888 1.0699763258347728 1.1960515229649522 1.1337292834338601 1.150157475966873 1.2033714368716901 1.0 14.334846301858088 -6.739260320381596 24.93898924646216 1.1458635186550996 1.0870886567042128 0.02977167460977781 0.09567443851016746 650.7522749472173 731729.1622542596 0.0316185779487771 0.03159306560536311 1.8228027688968967e-07 6.739260320381596 -0.05877486195088677 RS(ph)SDPLGDTASNLGSAVDELMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSDPLGDTASNLGSAVDELMR 22 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 RS(0.5)S(0.5)DPLGDTASNLGSAVDELMR 82.03399999999999 0.00014114 6330800.0 15307.0 15343.0 15548.0 19793.0 20223.0 17938.0 17405.0 17148.0 18047.0 14025.0 True False 17898.172772969185 16866.151641645498 15918.72328611836 18684.0623797718 16260.448322020193 16997.29970195576 15756.272398712243 16697.88316980785 18310.903233430327 16567.62147816108 1.0803103388474922 1.0180188908756715 0.960833352397743 1.1277456093743177 0.9814594293727803 1.0259348165553557 0.9510280289468025 1.0078624256244915 1.1052222105368104 1.0 14.016078877222315 RS(ph)SDPLGDTASNLGSAVDELMR ddPTM_PC-9_Lapatinib_30min_R1 2 RSSDPLGDTASNLGSAVDELMR 22 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 RS(0.5)S(0.5)DPLGDTASNLGSAVDELMR;RS(0.5)S(0.5)DPLGDTASNLGSAVDELMR 228.65 5.6469e-42 15849300.0 18029.4 24312.0 26116.0 19193.6 25772.2 25972.6 23240.0 21602.5 25053.0 17020.8 True False 17772.297449812984 24255.70705772484 23968.84329067533 20605.161371972645 24256.3298660947 24861.812443087714 24443.253485806665 22606.231013803503 22231.26732021436 19962.82260120961 0.8902697682008207 1.2150439615816209 1.2006740614537637 1.032176750933213 1.2150751599939045 1.2454056693155837 1.2244387466692999 1.132416565803361 1.1136334657839067 1.0 14.285028101470475 -4.754581361311005 24.995188661080302 1.1620868819957788 0.890269302556485 0.4888927470911255 0.08019216760779736 196.60869143037544 716509.6557921921 0.01972548236428681 0.18897492937405352 1.7596189835395127e-05 4.754581361311005 -0.27181757943929385 RS(ph)SDSWEVWGSASTNR ddPTM_PC-9_AZD4547_30min_R2 2 RSSDSWEVWGSASTNR 16 1 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHH7 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 RS(0.499)S(0.499)DS(0.001)WEVWGSASTNR;RS(0.496)S(0.496)DS(0.007)WEVWGSASTNR 102.72 0.00067069 55364000.0 47881.0 33367.0 48810.0 89606.0 65793.0 52267.0 47228.0 64312.0 49883.0 58994.0 True False 63106.16201333077 44152.23022275157 48162.74750811258 68948.72109889962 56658.77761984687 48998.73622747699 51431.20050724093 54374.058142739676 52519.71354183712 56928.63801637607 1.1085134690061913 0.7755715183288023 0.8460196692964639 1.211142994130052 0.995259672355914 0.860704522974571 0.903432829228169 0.9551266293618066 0.9225534875211544 1.0 15.796866964075194 -6.716757870085044 24.99303110070151 0.92400038282628 0.9801253786246672 0.05576052394943409 0.11877904016111179 503.1881569047145 281461.5102125271 0.0412646605867006 0.041264482158815896 1.9197387441961564e-07 6.716757870085044 0.056124995798387145 RS(ph)SDSWEVWGSASTNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RSSDSWEVWGSASTNR 16 1 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHH7 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 RS(0.488)S(0.488)DS(0.024)WEVWGSASTNR;RS(0.486)S(0.486)DS(0.028)WEVWGSASTNR;RS(0.712)S(0.219)DS(0.069)WEVWGSASTNR 93.804 0.0012342 37117500.0 54954.0 62968.0 67655.0 76381.0 79377.0 66814.0 72204.0 77291.0 59631.0 47144.0 True False 64256.62680902524 69219.04689898551 69268.1517830164 72101.62020054302 63823.64666256229 63310.15622067513 65364.31440830911 75262.19314658396 60502.99056423145 55690.83400830134 1.1538097418229916 1.2429163278227733 1.2437980686856154 1.294676610334036 1.1460350307026945 1.1368146544768578 1.1736996863535178 1.3514287312588154 1.0864084124725588 1.0 15.765152277690405 -8.515358930046663 23.297117160979134 0.999999991789044 1.2157910789035895 0.5506839807877904 0.06546542904513822 135.9876829819026 421301.4311130401 0.06447058632145025 0.016646233809948743 3.0523973648455907e-09 8.515358930046663 0.21579108711454553 RS(ph)SDSWEVWGSASTNR ddPTM_PC-9_Lapatinib_30min_R1 2 RSSDSWEVWGSASTNR 16 1 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHH7 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 RS(0.603)S(0.396)DS(0.001)WEVWGSASTNR;RS(0.843)S(0.156)DSWEVWGSASTNR 116.69 7.1094e-05 34965000.0 57289.0 50632.0 63656.0 53140.0 55331.0 46116.0 46899.0 43581.0 60778.0 54038.0 True False 56472.048354484104 50514.764714820805 58422.44939926593 57048.09286984335 52076.539364931465 44143.72618164656 49327.20074143061 45605.932360262464 53932.54161928664 63378.39629889106 0.8910299353136553 0.7970344417772002 0.9218038450160053 0.9001189080393555 0.8216765081801645 0.6965106212764641 0.778296763913127 0.7195816717290532 0.8509609704376554 1.0 15.951703534364128 -6.516324510819376 24.731270299294625 0.7862286495500034 0.8731622031441219 0.10051272881647966 0.0846462567789512 432.91543550236963 1633540.6535457505 0.026106040439408354 0.02704570854345201 3.045618411157657e-07 6.516324510819376 0.08693355359411847 RS(ph)SDSYPLAPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RSSDSYPLAPVR 12 1 Q52LW3 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 RS(0.944)S(0.051)DS(0.005)YPLAPVR;RS(0.937)S(0.063)DS(0.001)YPLAPVR;RS(0.493)S(0.493)DS(0.014)YPLAPVR;RS(0.909)S(0.091)DSYPLAPVR 103.66 0.00092919 28768000.0 88683.0 80042.0 64826.0 76829.0 84123.0 60005.0 61803.0 62999.0 56930.0 45363.5 True False 103695.28033090902 87988.04078085051 66371.69769397394 72524.52021297866 67639.70203200837 56858.23216723462 55948.57242502801 61345.34300295811 57762.49354902139 53587.54345273158 1.9350631443364519 1.641949511241598 1.2385657825968266 1.353383931042687 1.2622280790249676 1.0610344961490545 1.0440592872927463 1.1447687102333681 1.0779089659142977 1.0 15.70961006143569 -1.522878745281004 0.4371622554327415 1.0539524168460628 20.054951402022816 0.9337575418539477 0.0731829744426132 19.697521637692613 0.24396623357925182 0.049251365339587606 331.27187266971936 0.029999999999953966 1.522878745281004 19.000998985176754 RS(ph)SDSYPLAPVR ddPTM_PC-9_Lapatinib_30min_R1 2 RSSDSYPLAPVR 12 1 Q52LW3 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 RS(0.498)S(0.498)DS(0.004)YPLAPVR;RS(0.929)S(0.07)DS(0.001)YPLAPVR 156.96 3.1606e-05 66516000.0 54327.0 60305.0 62171.0 44242.0 47591.0 38441.0 43680.0 46540.0 49372.0 48702.0 True False 53552.28701764839 60165.367477628184 57059.54036700012 47495.70426698549 44791.79094750599 36796.96804034771 45941.53667211854 48702.41830262306 43811.20544979137 57120.07580866416 0.9375387945392994 1.0533138590215614 0.998940207259759 0.831506324082665 0.7841689688498598 0.644203767579143 0.8042975437569356 0.8526322420467747 0.7670018785784934 1.0 15.801710273634797 -5.809149561629661 3.9607468248545254 0.7941964822755572 1.0046896463571917 0.4804157542114533 0.08730016295406792 0.16517524459138747 5.365202144832934 0.024569724517494215 0.03952870008821025 1.5518524934793464e-06 5.809149561629661 0.21049316408163454 RS(ph)SELLVR ddPTM_PC-9_AZD4547_30min_R2 1 RSSELLVR 8 1 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 RS(0.993)S(0.007)ELLVR 122.96 0.0015154 3353900.0 6255.0 4789.5 5272.0 9491.6 8098.0 4401.3 5522.4 9875.5 8070.9 6717.6 True False 8243.959887917626 6337.612211222726 5202.089835336392 7303.458263758177 6973.732481654886 4126.086015229393 6013.882901693642 8349.468391414135 8497.511296931083 6482.418868678303 1.2717413136862727 0.9776616321177188 0.8024920852417924 1.1266563317972194 1.0757917103059336 0.6365040733738729 0.9277220468969495 1.2880174145729808 1.3108550170969802 1.0 12.662316529668473 -7.757850085775729 24.966560735011683 1.2245771874902307 0.9644158810984045 0.23997244763133718 0.18175431563160238 115.88375482727778 806087.3910004759 0.09147149497761248 0.050127094081100144 1.7464248977447874e-08 7.757850085775729 -0.2601613063918262 RS(ph)SELLVR ddPTM_PC-9_Lapatinib_30min_R1 1 RSSELLVR 8 1 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 RS(0.76)S(0.24)ELLVR 135.43 0.0016928000000000002 2581300.0 10347.0 7713.0 9442.0 6615.2 4809.5 5406.8 3907.1 4574.1 6980.1 6418.5 True False 10199.449882592591 7695.141022385308 8665.715207174007 7101.703875660291 4526.614665840809 5175.563767866398 4109.390520412875 4786.62938457302 6193.927634288435 7527.9291728863445 1.3548812227575644 1.0222121974926675 1.1511419685490234 0.943380804011652 0.6013094121746662 0.6875149392355392 0.5458859171010585 0.6358494181657848 0.8227930274101624 1.0 12.878037339082638 -5.989222695833301 2.776531066696316 0.6877854338258444 1.1642732661329434 0.6714576454767479 0.14350069304631052 0.14868710788860218 2.326237368475055 0.04220929620584971 0.06362927671760156 1.025126131269594e-06 5.989222695833301 0.4764878323070989 RS(ph)SFSEGQTLTVTSGAK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSFSEGQTLTVTSGAK 17 1 E9PEM3;H7C357;H0Y6E6;Q92622-3;Q92622-2;Q92622;H7C3H3 E9PEM3 KIAA0226 Run domain Beclin-1 interacting and cysteine-rich containing protein 1 RS(0.499)S(0.499)FS(0.002)EGQTLTVTSGAK 140.8 2.5555e-08 0.0 28206.0 30071.0 31814.0 28667.0 31504.0 29174.0 26664.0 32818.0 31569.0 25025.0 True False 27803.777267653088 30001.37244705672 29198.375725591373 30775.266810308625 29650.99665924707 27926.29602791563 28044.531452045998 34342.84408799921 28013.36678369245 29350.53790628352 0.9473004330084426 1.0221745353646097 0.9948156936278987 1.0485418328132272 1.0102369078864215 0.9514747606018157 0.9555031509675356 1.1700924936250288 0.9544413418636256 1.0 14.841099323348711 RS(ph)SGENVENNSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSGENVENNSQR 13 1 Q9NVW2-2;Q9NVW2 Q9NVW2-2 RLIM E3 ubiquitin-protein ligase RLIM 1 RS(0.841)S(0.159)GENVENNSQR 94.007 0.0056949 1092800.0 1991.2 2226.6 4637.9 2975.7 4090.3 3884.1 4620.0 3958.3 3978.0 3514.0 True False 2328.2708320073334 2447.6421329132413 4748.4851253336965 2808.9811763495645 3288.8350774642304 3680.4109584327316 4182.360154096556 3854.398819165527 4036.1707243633778 4151.060383191304 0.5608858019592036 0.5896426230811685 1.1439209953585634 0.6766900302688541 0.7922879394338751 0.8866194703733168 1.0075401868476768 0.9285335464579039 0.9723228167691457 1.0 12.019264202847173 -5.158312769266409 8.434847298103351 0.9110515852429801 0.5700430138095204 0.5731526090139738 0.1205715356682225 0.229042361060338 16.961184252456803 0.030987551397402988 0.082712811481258 6.945239566658466e-06 5.158312769266409 -0.34100857143345975 RS(ph)SGFISELPSEEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSSGFISELPSEEGK 15 1 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 RS(0.488)S(0.488)GFIS(0.025)ELPSEEGK;RS(0.498)S(0.498)GFIS(0.004)ELPSEEGK 78.508 0.0054210000000000005 70435000.0 143015.0 152208.0 158215.0 221165.0 237567.0 221633.0 242032.0 220968.0 216999.0 192101.0 True False 167224.61482499447 167318.2043323718 161987.44563372852 208773.84207660452 191017.45173897862 210010.1753174023 219104.97680006424 215167.82413494855 220172.19985322453 226927.39062932078 0.736908023140102 0.7373204436377676 0.7138294111808223 0.920002832173003 0.8417558198207991 0.9254509767859964 0.9655290011154527 0.9481791666410991 0.9702319285593397 1.0 17.79187123038465 -6.036307487062691 0.668567686599512 0.9778916540681125 0.6908359941070211 0.8536261743892085 0.03974374146436145 0.34273141146427677 0.3000330619546299 0.023655725676227847 0.05977215303058662 9.197981101824125e-07 6.036307487062691 -0.2870556599610914 RS(ph)SGFISELPSEEGK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSGFISELPSEEGK 15 1 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 RS(0.483)S(0.483)GFIS(0.033)ELPSEEGK 68.97800000000001 0.012236 15936000.0 71059.0 74163.0 78130.0 76053.0 84663.0 85966.0 70677.0 79962.0 89415.0 61899.0 True False 70045.6856293754 73991.28013006129 71706.45299052175 81646.19132537082 79683.28879386223 82289.43457653381 74336.30923478297 83677.32643563258 79344.14111830786 72598.1596747669 0.9648410640596629 1.0191894734182718 0.9877172274305587 1.12463169440022 1.0975937840688532 1.1334920188773783 1.023942060898001 1.1526094712386559 1.0929222100637583 1.0 16.147645356672143 -5.753163248055654 24.996223865877795 1.0951337948047228 0.9934432439836639 0.48698842396887043 0.046139271505469065 141.96742157320813 428776.68644150684 0.011815247284633018 0.020026693223842176 1.765374104995757e-06 5.753163248055654 -0.10169055082105893 RS(ph)SGREEDDEELLR ddPTM_PC-9_AZD4547_30min_R2 1 RSSGREEDDEELLR 14 2 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 RS(0.5)S(0.5)GREEDDEELLR 81.23899999999999 0.003406 10863000.0 26903.0 22318.0 23365.0 30879.0 38732.0 27601.0 17719.0 33966.0 32255.0 33674.0 True False 35457.59438283741 29531.85704772289 23055.164833580217 23760.323625794263 33354.73036298558 25875.105106751726 19295.95667374866 28717.335161032104 33959.933450112396 32495.083509567907 1.0911679722994776 0.9088100062591771 0.70949701750395 0.7311974938854438 1.0264546743868055 0.7962775383892464 0.5938115736205795 0.8837440024604498 1.0450791252810037 1.0 14.987933835139115 -8.152244953919606 4.894432749032479 1.020004879499713 0.8305536455551019 0.21165949329871192 0.14000555608435775 0.34908272863227974 12.435075913057137 0.10627987764560205 0.03781264152722914 7.042957149475443e-09 8.152244953919606 -0.18945123394461105 RS(ph)SGREEDDEELLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSGREEDDEELLR 14 2 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 RS(0.5)S(0.5)GREEDDEELLR 89.44 0.0017017 7558700.0 24706.0 29249.0 29411.0 28811.0 25724.0 25887.0 21710.0 24377.0 19861.0 24060.0 True False 28888.23783425731 32152.647420093148 30112.269781838648 27196.81307652228 20683.566861279098 24529.44014854101 19653.471633211302 23737.129579566496 20151.429551679495 28421.887541144803 1.01640813941148 1.1312636211633562 1.0594746650181757 0.956896794315682 0.7277337520717664 0.8630475408443964 0.6914907254052023 0.8351707656714762 0.7090109522989062 1.0 14.794714748902237 -6.0121106718456385 3.0479554973186582 0.7937321600600418 1.0746473551861926 0.6422639769949678 0.08889357167880059 0.14122612236790716 2.6809955632602165 0.024971099218354817 0.036561987532186646 9.724993688784609e-07 6.0121106718456385 0.2809151951261508 RS(ph)SGREEDDEELLR ddPTM_PC-9_Lapatinib_30min_R1 2 RSSGREEDDEELLR 14 2 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 RS(0.5)S(0.5)GREEDDEELLR;RS(0.593)S(0.407)GREEDDEELLR 66.98899999999999 0.011303 11665300.0 40011.0 34967.0 40808.0 30254.0 33350.0 33130.0 28971.0 30056.0 40833.0 31852.0 True False 39440.43580288121 34886.03605986608 37452.92376343537 32478.980084385435 31388.41856862274 31713.107129802025 30470.976623808303 31452.51148482249 36233.957549447645 37357.57575987785 1.0557546896616445 0.9338410041406858 1.0025523070386146 0.8694081300443472 0.8402156170512005 0.8489069883346659 0.8156572262521976 0.8419312775269155 0.9699226144209021 1.0 15.18911321701996 -5.764318851368551 24.935072646528265 0.871034847772524 0.991028516145622 0.39671770552173424 0.06273699306289082 65.18906417059014 564519.4948084799 0.016938798281833395 0.02642808785500392 1.7206048733197112e-06 5.764318851368551 0.119993668373098 RS(ph)SGYTPR ddPTM_PC-9_Lapatinib_30min_R1 1 RSSGYTPR 8 1 F8W824 F8W824 KCNQ1 1 RS(0.999)S(0.001)GYTPR 62.464 0.028350999999999998 8662200.0 4563.8 3705.4 4152.6 4140.2 4352.1 2384.1 4173.6 3389.7 5735.5 4207.7 True False 4498.719375101578 3696.8203739590995 3811.189257499555 4444.684119302325 4096.118034557813 2282.1376006085434 4389.688586418362 3547.1978367082365 5089.507592507458 4934.9953385921735 0.9115954659411992 0.7491031136442181 0.7722781879236361 0.9006460623264293 0.8300145701305424 0.46243966691558785 0.889502073505631 0.7187844351075234 1.0313095035180646 1.0 12.268833006629853 -8.267855283028046 24.336505727088383 1.015654818144307 0.7769024785737367 0.3694112390133194 0.1234921655899114 408.39721163268746 1549080.132664663 0.10861201870711396 0.030803365866785885 5.3969042989640576e-09 8.267855283028046 -0.2387523395705703 RS(ph)SIGLR ddPTM_PC-9_AZD4547_30min_R2 2 RSSIGLR 7 1 Q96GN5-5;Q96GN5-4;Q96GN5-2;Q96GN5;C9J8L0;C9IZR6 Q96GN5-5 CDCA7L Cell division cycle-associated 7-like protein 1 RS(0.993)S(0.007)IGLR;RS(0.999)S(0.001)IGLR 107.69 0.0045245 32019000.0 32045.0 41871.0 43150.0 63909.0 56983.0 53452.0 38299.0 53794.0 35838.0 42001.0 True False 42234.64342259318 55404.98191796781 42577.802806290834 49175.767434207206 49071.89404817741 50109.63799014867 41707.53680500595 45481.37336314432 37732.3235152729 40530.55777410945 1.0420444657579393 1.3669928311068051 1.0505111487384746 1.2133010285296453 1.210738187262848 1.236342175931224 1.0290393001116884 1.1221501963192178 0.9309598877362592 1.0 15.306722409175618 -7.702564323463391 1.3722815975851148 0.982974429403332 1.1893364495467262 0.39715478278829897 0.09845667461905387 0.42984481546644077 1.5059886842214854 0.07341897873681076 0.029716837477323593 1.983515856054369e-08 7.702564323463391 0.20636202014339422 RS(ph)SIGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RSSIGLR 7 1 Q96GN5-5;Q96GN5-4;Q96GN5-2;Q96GN5;C9J8L0;C9IZR6 Q96GN5-5 CDCA7L Cell division cycle-associated 7-like protein 1 RS(0.998)S(0.002)IGLR;RS(0.998)S(0.002)IGLR;RS(0.996)S(0.004)IGLR 100.25 0.0053094 15661600.0 33252.8 28858.3 29587.5 29819.2 35320.0 31352.5 29090.7 40446.0 32565.0 25405.899999999998 True False 38881.842267262706 31723.161306139515 30292.978211218608 28148.526899150787 28399.299546741495 29708.31970707815 26335.018297570725 39384.335356079355 33041.20151807274 30011.78855700624 1.2955523191631229 1.0570233508703617 1.0093693067868401 0.9379156742252712 0.9462714790489116 0.9898883450630854 0.8774891322304357 1.3122955095218776 1.1009407671692824 1.0 14.87324167867338 -10.461007609785256 11.859121198906422 0.999969855777726 1.0503085426465981 0.012856009059624696 0.13785478948889365 0.0 0.0 0.13902038175336776 0.033717395181342674 3.459333162678412e-11 10.461007609785256 0.05033868686887211 RS(ph)SIGLR ddPTM_PC-9_Lapatinib_30min_R1 3 RSSIGLR 7 1 Q96GN5-5;Q96GN5-4;Q96GN5-2;Q96GN5;C9J8L0;C9IZR6 Q96GN5-5 CDCA7L Cell division cycle-associated 7-like protein 1 RS(0.999)S(0.001)IGLR;RS(0.987)S(0.013)IGLR;RS(0.902)S(0.098)IGLR 114.72 0.0039148 39032700.0 43566.0 40055.6 50896.0 30101.2 46959.0 49903.0 41152.0 35657.1 52352.9 49727.4 True False 42944.74085097408 39962.853719208746 46711.52734424151 32314.942662659567 44196.96394494614 47768.76501957472 43282.649201717555 37313.85903864332 46456.36510152274 58322.714832404556 0.7363295925846313 0.685202220679293 0.800914831870759 0.5540713040454203 0.7578001825180806 0.8190422060571505 0.7421233618169876 0.6397826155018327 0.79653982560687 1.0 15.83177025600593 -14.522878745280336 0.3233173501948619 3.684761241454578 0.7122012667695242 0.5450552486474609 0.07600236734561433 258.68745358469454 2.274218641723844 475.7056133188867 0.06655884863014959 3.0000000000000132e-15 14.522878745280336 -2.972559974685054 RS(ph)SITEPEGPGGPNIQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSITEPEGPGGPNIQK 17 1 H0YJL1;A0A3B3ISJ2;Q96KQ4 H0YJL1 PPP1R13B Apoptosis-stimulating of p53 protein 1 1 RS(0.487)S(0.487)IT(0.026)EPEGPGGPNIQK 158.53 1.3115e-05 12561000.0 28942.0 29751.0 35424.0 37407.0 45267.0 38457.0 34210.0 48138.0 37827.0 27628.0 True False 33841.30896944368 32704.48266249075 36268.64250626811 35311.20706513028 36397.25630187844 36440.247220320685 30969.381141048296 46874.42850642699 38380.1483133468 32636.737696872347 1.036908446051174 1.0020757272447882 1.111282715911395 1.0819465901616212 1.115223483423298 1.11654073880714 0.9489116660093193 1.436247364604676 1.175979923907188 1.0 14.994209235150436 -7.739813656951716 24.999918451041257 1.2295855363277577 1.0640668488679206 0.25326860492654446 0.11137912032188779 259.8952580836493 300446.4434162173 0.049663934049078984 0.02864085619672444 1.820481806505924e-08 7.739813656951716 -0.1655186874598371 RS(ph)SITEPEGPGGPNIQK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSITEPEGPGGPNIQK 17 1 H0YJL1;A0A3B3ISJ2;Q96KQ4 H0YJL1 PPP1R13B Apoptosis-stimulating of p53 protein 1 1 RS(0.473)S(0.473)IT(0.053)EPEGPGGPNIQK 125.75 1.7338e-05 9966300.0 63772.0 62481.0 60393.0 59789.0 56177.0 51346.0 41449.0 53173.0 58668.0 36598.0 True False 62862.5995856475 62336.32908332119 55427.72066372162 64186.0825102572 52872.779308231475 49150.051273372024 43595.0264084854 55643.6116975801 52060.192038571615 42923.91553623032 1.464512237533124 1.4522516947622275 1.2913015965875096 1.4953454667032962 1.2317790361786478 1.1450505076100637 1.0156348940647928 1.296331217747682 1.2128481614085216 1.0 15.389494064848114 -6.4453239699849565 3.955446786546796 1.147545572714846 1.4172949856233583 0.6723152951915058 0.09579020576846714 0.15213795960124682 4.486786851684519 0.031379006832872154 0.035055615910861815 3.5865429004252486e-07 6.4453239699849565 0.2697494129085123 RS(ph)SITEPEGPNGPNIQK ddPTM_PC-9_AZD4547_30min_R2 1 RSSITEPEGPNGPNIQK 17 1 Q13625-2;Q13625;Q13625-3 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 RS(0.429)S(0.429)IT(0.142)EPEGPNGPNIQK 84.62 0.0015468 68739000.0 24787.0 26415.0 39560.0 58119.0 37737.0 44206.0 35172.0 32585.0 25479.0 36501.0 True False 32668.75039837157 34953.132176521234 39035.408551955195 44720.562479598964 32497.86893803537 41441.791831783914 38302.23986280763 27549.73697880912 26825.76792359057 35223.111100039714 0.9274805483702641 0.9923351766755727 1.1082328429504111 1.2696369253864275 0.9226291466910976 1.1765511488772833 1.0874178534094465 0.782149450131282 0.7615956423440496 1.0 15.10423472115396 -7.7566911626291235 24.992218473092176 0.8289043847014954 1.0739321854763606 0.42543472994702547 0.11712317763530801 100.60464412582223 529540.7423663082 0.0573171678290598 0.03170118830552974 1.7510914897240166e-08 7.7566911626291235 0.2450278007748652 RS(ph)SITEPEGPNGPNIQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSITEPEGPNGPNIQK 17 1 Q13625-2;Q13625;Q13625-3 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 RS(0.472)S(0.472)IT(0.055)EPEGPNGPNIQK 55.302 0.024152 75145000.0 16425.0 12370.0 15760.0 21465.0 21446.0 22288.0 21701.0 22325.0 17849.0 17496.0 True False 19205.42809146267 13598.011849518014 16135.778170132839 20262.385640468947 17243.81025139915 21119.178044218414 19645.324178365652 21738.992405292774 18110.007858009532 20667.886301740196 0.9292400689201396 0.6579294878534864 0.7807173861206231 0.9803801581181958 0.8343286778168145 1.0218354086087758 0.9505241073786802 1.0518246562766504 0.8762389919130097 1.0 14.33510323188689 -5.756296116337526 24.6617792378049 0.9584962087951155 0.7761589597371592 0.4464687488209108 0.08637344689743913 88.56237294470077 424646.1528813422 0.0226663913894264 0.037763751153245734 1.7526850557179441e-06 5.756296116337526 -0.18233724905795634 RS(ph)SLLNAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RSSLLNAK 8 1 E9PCH4;Q8TEU7;A0A5F9ZHG7;Q8TEU7-4;B7Z7Y1;Q8TEU7-2;Q8TEU7-5;Q8TEU7-3;D6RE77 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 1 RS(0.663)S(0.337)LLNAK;RS(0.988)S(0.012)LLNAK;RS(0.96)S(0.04)LLNAK 99.973 0.0023083 66508000.0 268669.0 268188.0 265594.0 285542.0 339109.0 287273.0 298124.0 297626.0 292806.0 235391.0 True False 314149.35524536937 294811.9322472541 271926.7682308542 269544.0074796542 272663.02576432546 272207.898164786 269883.53648915177 289813.63286081306 297087.73381547036 278065.52494586917 1.1297673643883923 1.0602246801527984 0.9779233448079908 0.96935428270774 0.9805711291157169 0.9789343652643617 0.9705753222794873 1.0422494227475012 1.0684090876540853 1.0 18.085065362333417 -4.9585948105913555 2.8693661046916783 0.9968635584282984 1.1323015541852626 0.6366452583133044 0.031249992081983334 0.20678998916077843 3.059156580401322 0.00905050188205515 0.054417105924332305 1.1000316717666224e-05 4.9585948105913555 0.13543799575696414 RS(ph)SLLSLMTGK ddPTM_PC-9_AZD4547_30min_R2 1 RSSLLSLMTGK 11 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 RS(0.916)S(0.084)LLSLMTGK 75.764 0.0079526 2668100.0 17767.0 19118.0 21517.0 23143.0 26050.0 21779.0 16590.0 29632.0 18856.0 18901.0 True False 23416.53642344244 25297.51962713353 21231.670521041953 17807.738905785693 22433.407155731027 20417.155687110848 18066.47786091147 25053.055275619812 19852.689664713052 18239.28174301666 1.2838518946837374 1.3869800348261674 1.1640628627917873 0.9763399215324806 1.2299501412285703 1.1194056857490036 0.9905257298757746 1.373576856183603 1.0884578649767347 1.0 14.154761297309188 -5.360901534787423 5.301401679424355 1.1234352906101088 1.333918578582616 0.3612060042566312 0.11642279523674479 0.22870385933191995 9.61590766655325 0.03006808307567092 0.06462597817162215 4.356106261051006e-06 5.360901534787423 0.21048328797250715 RS(ph)SLLSLMTGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSLLSLMTGK 11 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 RS(0.871)S(0.128)LLSLMTGK 83.633 0.0046966 47488000.0 329070.0 317850.0 259600.0 252880.0 300700.0 184050.0 141350.0 228180.0 137140.0 112700.0 True False 384775.05157124065 349404.0474025301 265789.8485384826 238711.95344802178 241779.99359301163 174398.09399849223 127960.30471462056 222190.51677669497 139145.41305660972 133131.61786729112 2.890185349920362 2.6245008736453928 1.9964442166054686 1.7930522987107071 1.8160974640451217 1.309967510289979 0.961156386172476 1.6689537792455882 1.0451718028042993 1.0 17.022493716785746 -3.888807824062041 0.3511785255466605 1.0559982815866846 6.097957594723524 0.8924063837060915 0.20740086913177203 3.6928090891228544 0.2239674225923825 0.18992775373874196 8.90758849814554 0.0001291790766448224 3.888807824062041 5.041959313136839 up RS(ph)SLLSLMTGK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSLLSLMTGK 11 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 RS(0.498)S(0.498)LLS(0.004)LMTGK 52.372 0.037269 1861100.0 21617.0 23947.0 24762.0 21856.0 19487.0 16565.0 13312.0 10138.0 22462.0 18093.0 True False 21308.73761592772 23891.552192799285 22726.16394408417 23463.363149478668 18340.81297291608 15856.553564901013 14001.230223883756 10609.048490588584 19932.09302465391 21220.35094259293 1.004165184335259 1.1258792211982127 1.070960796339556 1.105700994905962 0.8643029996314944 0.7472333331242961 0.6598020108979845 0.4999468915141446 0.9392913943118036 1.0 14.373160895319177 -6.4619387841073115 2.689275586294418 0.7313599518447451 1.0809594072959163 0.5244644971658735 0.1357068028519465 0.19660298932207143 2.810018325177361 0.04535618841604823 0.050350912344232404 3.451923924321449e-07 6.4619387841073115 0.3495994554511712 RS(ph)SLNSISSSDAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSLNSISSSDAK 13 1 Q14123-2;Q14123;A0A0A0MS69;Q14123-3 Q14123-2 PDE1C Calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase 1C 1 RS(0.772)S(0.222)LNS(0.005)IS(0.001)SSDAK 88.507 0.011458 0.0 15329.0 16664.0 13919.0 12932.0 21691.0 12989.0 15881.0 14750.0 10177.0 8356.6 True False 17923.89693844939 18318.29179146064 14250.881748101461 12207.461966109682 17440.804260146353 12307.833974172328 14376.636711516754 14362.828128916826 10325.819372007563 9871.585429190798 1.8157060045742484 1.8556585386266817 1.4436264418034466 1.2366262799095649 1.766768305380104 1.2467940496951397 1.456365526555064 1.4549667053931568 1.0460142847443301 1.0 13.269066092458843 -1.5228787454126127 0.12118321292052701 0.8514660272765033 3.930897747224083 0.5995474398229601 0.18429140317046175 68.90101782599963 0.5751169611872098 1.2653631734116053 35.851408867598764 0.029999999990862756 1.5228787454126127 3.0794317199475794 RS(ph)SLPLDHGSPAQENPESEK ddPTM_PC-9_AZD4547_30min_R2 1 RSSLPLDHGSPAQENPESEK 20 1 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5;X6R5W5;A0A0A0MRX3 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 RS(0.5)S(0.5)LPLDHGS(0.001)PAQENPESEK 115.38 8.9491e-06 4767100.0 27517.0 26959.0 51865.0 97470.0 61389.0 57357.0 34548.0 65434.0 43925.0 51275.0 True False 36266.83361084399 35672.96953802139 51177.236212011005 74999.79739648844 52866.19700127338 53770.45772283468 37622.70507165581 55322.678823734714 46246.78582533522 49479.87785689537 0.732961259842519 0.7209591268837401 1.0343040126336749 1.515763592088914 1.0684383084811133 1.0867136309096888 0.7603637418117195 1.1180843854089084 0.9346584476034716 1.0 15.594554318516343 -5.284859740046546 5.700789793376482 1.076413706874232 0.7247065812201046 0.36179507632763996 0.17937016437764738 0.17752224054063356 20.017382124260735 0.04993335212759146 0.11317603173117922 5.189676178967385e-06 5.284859740046546 -0.35170712565412754 RS(ph)SLPSFETLDYGDEEDIETQLSSSGK ddPTM_PC-9_AZD4547_30min_R2 1 RSSLPSFETLDYGDEEDIETQLSSSGK 27 1 K7EPU8;K7EQI2;A0A0C4DGP8;K7EJF0;Q96ST8-3;Q96ST8 K7EPU8 CEP89 Centrosomal protein of 89 kDa 1 RS(0.275)S(0.199)LPS(0.086)FET(0.275)LDY(0.165)GDEEDIET(0.001)QLSSSGK 55.871 0.0017492999999999999 4776600.0 11217.0 9524.2 12202.0 17923.0 16084.0 14095.0 11376.0 12952.0 12485.0 13171.0 True False 14783.772671906005 12602.71139411786 12040.19350735483 13791.129257589639 13851.014230049053 13213.637421820436 12388.441961767874 10950.566007351112 13144.931611367329 12709.887298940397 1.1631710277351164 0.9915675172956512 0.9473092266017655 1.0850709320403953 1.0897826160271138 1.0396345074532671 0.9747090332422286 0.8615785293598979 1.0342288096026784 1.0 13.633663617289594 -7.293923148140751 4.254482509108742 0.9541541036327854 1.0488163106570936 0.26497405130057716 0.06848717476122329 0.2895611477606363 12.272539714360342 0.0296559308715107 0.02021846577900521 5.0824937336824124e-08 7.293923148140751 0.09466220702430816 RS(ph)SMESPK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSMESPK 8 1 Q5T1R4-2;Q5T1R4 Q5T1R4-2 HIVEP3 Transcription factor HIVEP3 1 RS(0.995)S(0.005)MESPK 68.22399999999999 0.042497 1051000.0 5730.9 6591.3 4098.4 5444.5 6099.5 4071.7 6187.7 6069.4 5442.1 6059.2 True False 5649.176315081657 6576.038249818262 3761.445372281502 5844.906692319572 5740.739402078392 3897.562882596289 6508.068829351378 6351.406481434048 4829.153390146427 7106.524646623505 0.794928125348264 0.925352204743666 0.5292946354683598 0.8224704736789508 0.8078124945089675 0.5484485140634984 0.9157878362447572 0.8937429752603148 0.679537978165021 1.0 12.794928485735051 -10.65384582148643 4.036373137484459 1.0000662500656978 0.770442201386231 0.2104173441372421 0.13443418748086763 189235817.95822102 286779587.04839724 166094.74854182467 0.03308468284536739 2.2189840396169544e-11 10.65384582148643 -0.22962404867946684 RS(ph)SMGSTAVATDVK ddPTM_PC-9_AZD4547_30min_R2 1 RSSMGSTAVATDVK 14 1 Q6UXY1;B0QYF0;Q6UXY1-2 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 RS(0.516)S(0.324)MGS(0.128)T(0.032)AVATDVK 75.316 0.0065608 7419600.0 56893.0 69944.0 89452.0 106360.0 99752.0 104010.0 70812.0 109260.0 74991.0 96074.0 True False 74983.79055208592 92552.03017053186 88265.8080331014 81840.34524561923 85903.15664485552 97506.23825778946 77114.13081897899 92376.37754502652 78954.87116283923 92710.47850264967 0.8087952059264033 0.9982909339410508 0.9520585963816244 0.8827518374126418 0.9265744070385789 1.0517283464889324 0.831773625424391 0.9963962977754063 0.8516283427507356 1.0 16.500444786679317 -4.745147130699639 24.673969689791775 0.9410903166792677 0.8087947601299594 0.26244392403034744 0.06762379100917569 1115.4486471449363 1689195.0803769866 0.015752655761235034 0.4069946115933395 1.798261595139793e-05 4.745147130699639 -0.13229555654930825 RS(ph)SMGSTAVATDVK ddPTM_PC-9_Lapatinib_30min_R1 2 RSSMGSTAVATDVK 14 1 Q6UXY1;B0QYF0;Q6UXY1-2 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 RS(0.496)S(0.496)MGS(0.007)T(0.001)AVATDVK;RS(0.579)S(0.421)MGS(0.001)TAVATDVK 87.932 0.0056897 28628800.0 69720.0 67765.0 77083.0 70355.0 73474.0 66789.0 61264.0 55563.0 71118.0 61806.0 True False 68725.78001491787 67608.09430596903 70745.53328898469 75529.14139740005 69152.40377544181 63932.59016276332 64435.9501529458 58144.65982270401 63107.94193425951 72489.08474868172 0.9480845323566829 0.932665856388793 0.9759473931041909 1.0419381298475232 0.953969884089334 0.8819616137300725 0.8889055555928732 0.8021160706372613 0.870585442664279 1.0 16.14547615309784 -6.723690237926112 4.04819679343846 0.8754391511139056 0.9744554549641317 0.36470893955018047 0.053067939898959 0.2092261615628995 7.32927955563332 0.018528920866213754 0.017791081344421762 1.889338445951336e-07 6.723690237926112 0.09901630385022608 RS(ph)SMGSTAVATDVKK ddPTM_PC-9_Lapatinib_30min_R1 2 RSSMGSTAVATDVKK 15 2 Q6UXY1;Q6UXY1-2 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 RS(0.718)S(0.144)MGS(0.111)T(0.025)AVAT(0.001)DVKK;RS(0.636)S(0.353)MGS(0.009)T(0.002)AVATDVKK 56.122 0.021657 55838000.0 327750.0 193519.0 207312.0 223790.0 204145.0 209190.0 171089.0 126452.0 205558.0 175248.0 True False 323076.2248980105 193070.91864527145 190267.60760746207 240248.2631415552 192137.59246451224 200243.43134570768 179947.1512750937 132327.42155572202 182405.89341829825 205539.3832967186 1.5718458414931342 0.9393378317504848 0.925699029332933 1.1688672958346407 0.9347969687499773 0.9742338822562019 0.8754874534936222 0.6438056757458152 0.8874498429090613 1.0 17.649055328894036 -4.761347623744031 6.665196605022293 0.9230631614319327 1.5885487416062896 0.7125977865272368 0.12272678325524071 0.06901622412488516 15.441333467011612 0.03355567874646144 0.208278729219268 1.7324167586538758e-05 4.761347623744031 0.6654855801743569 RS(ph)SMIETGQGAEGGLSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSMIETGQGAEGGLSLR 18 1 P49796-1;P49796-4;P49796-6;P49796 P49796-1 RGS3 Regulator of G-protein signaling 3 1 RS(0.545)S(0.455)MIETGQGAEGGLSLR 56.93600000000001 0.013271999999999999 3367800.0 7222.4 4228.3 11345.0 11500.0 11555.0 8233.0 11864.0 11309.0 4138.0 3764.2 True False 8445.009671097714 4648.057680138803 11615.507826152098 10855.692283503036 9290.880698261546 7801.246986631823 10740.156032078257 11012.150732875962 4198.510421673114 4446.619662609195 1.8991976629146503 1.0453013823564592 2.612210782007007 2.4413359151866643 2.089425541920495 1.7544219156477607 2.415352975292726 2.476521845453774 0.9442027293176465 1.0 12.118493295078146 -8.273392317606062 24.616096799802424 0.9721009725898484 2.085311748683003 0.5143212883390395 0.4351632158425772 590.3170614643863 1215694.0504403492 0.4283201538776644 0.1142462980380033 5.3285332779524316e-09 8.273392317606062 1.1132107760931547 RS(ph)SNVSYK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSNVSYK 8 1 P11717 P11717 IGF2R Cation-independent mannose-6-phosphate receptor 1 RS(0.5)S(0.5)NVSYK 67.214 0.021516 6539100.0 85948.0 82074.0 56103.0 44759.0 47864.0 41506.0 39260.0 40852.0 65351.0 33732.0 True False 84722.36575906724 81883.96269561158 51490.42790384276 48050.726171646944 45048.733624244654 39730.885135211705 41292.69069934465 42750.133057558174 57990.48220346178 39562.53125493528 2.1414799071659103 2.0697351786710274 1.3014947797967178 1.214551360781618 1.1386716722940975 1.0042553869769246 1.0437322736824008 1.0805712299367916 1.4657930209212202 1.0 15.271847113839492 -5.2968662845476615 2.6807700533544025 1.1312932627891692 2.1621614016940627 0.8993103100824112 0.12816987253492604 0.07901180827271624 1.1002777527608405 0.03578624057070565 0.1065653521089857 5.0481670226233386e-06 5.2968662845476615 1.0308681389048935 RS(ph)SPAAFINPPIGTVTPALK ddPTM_PC-9_AZD4547_30min_R2 1 RSSPAAFINPPIGTVTPALK 20 1 Q6R954;F8WEE2;Q8WUT1;F8WCX5;F6VRR5;Q9BY77-2;Q9BY77 Q6R954 PDIP46;POLDIP3 Polymerase delta-interacting protein 3 1 RS(0.5)S(0.5)PAAFINPPIGTVTPALK 102.73 9.798e-05 16108000.0 67856.0 64567.0 98136.0 132720.0 111350.0 97916.0 68593.0 101930.0 85677.0 91535.0 True False 89432.79650752025 85437.02007349777 96834.65251907663 102123.4545035595 95890.97454090764 91793.29704114725 74697.64411775154 86179.06061838321 90205.71130693794 88330.3875110855 1.012480518058368 0.9672438045488636 1.0962779089690264 1.1561531357568533 1.0855944057629463 1.0392040568103151 0.8456619089141543 0.975644543703238 1.0212307887318743 1.0 16.4306222202517 -7.020521483101615 24.80193987980078 0.956294433755381 1.0648861409097208 0.36925106522544227 0.06384763415048839 791.7695023786271 956918.3663006196 0.026184908721376094 0.020547087488370332 9.538465580620474e-08 7.020521483101615 0.10859170715433974 RS(ph)SPAAFINPPIGTVTPALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSSPAAFINPPIGTVTPALK 20 1 Q6R954;F8WEE2;Q8WUT1;F8WCX5;F6VRR5;Q9BY77-2;Q9BY77 Q6R954 PDIP46;POLDIP3 Polymerase delta-interacting protein 3 1 RS(0.564)S(0.436)PAAFINPPIGTVTPALK;RS(0.5)S(0.5)PAAFINPPIGTVTPALK 87.05 0.00033964 13741000.0 67104.0 73227.0 79294.0 86788.0 89722.0 85953.0 88110.0 85575.0 82511.0 63175.0 True False 78463.38183558668 80496.4926196163 81184.66968416962 81925.54973049228 72141.618174766 81445.47336839119 79763.58293884141 83328.7469242074 83717.56727952411 74628.12740697505 1.0513915404535954 1.0786347643515006 1.0878561811076848 1.09778380587954 0.966681339615435 1.0913508913903012 1.0688139406722723 1.116586330376275 1.1217964350489589 1.0 16.187431865558295 RS(ph)SPAAFINPPIGTVTPALK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSPAAFINPPIGTVTPALK 20 1 Q6R954;F8WEE2;Q8WUT1;F8WCX5;F6VRR5;Q9BY77-2;Q9BY77 Q6R954 PDIP46;POLDIP3 Polymerase delta-interacting protein 3 1 RS(0.499)S(0.499)PAAFINPPIGT(0.001)VTPALK 45.236999999999995 0.03847 14810000.0 36560.0 24011.0 43814.0 37213.0 36732.0 34831.0 38093.0 32749.0 34971.0 20416.0 True False 36038.64769571712 23955.404004731434 40211.78204693092 39949.768158928884 34571.49597789056 33341.3593250267 40065.26914951953 34270.63809610233 31032.197719044267 23944.878397389984 1.5050670585007175 1.0004395765627525 1.6793479331811536 1.668405556124413 1.4437950113648892 1.3924213258339597 1.6732291759680302 1.4312304087473613 1.2959847698548683 1.0 14.547429488502862 -8.592852316891681 2.2078975753054495 1.001743224999855 1.4752042696288281 0.37740848733054677 0.18811394229796213 0.42458446588743554 4.7180256032588135 0.18567024175866284 0.05102969239705246 2.553569503811356e-09 8.592852316891681 0.4734610446289731 RS(ph)SPPGHYYQK ddPTM_PC-9_AZD4547_30min_R2 1 RSSPPGHYYQK 11 1 D6RI08;D6RDK1;D6RIV2;D6R9T5;D6RG39;D6RIT9;D6RDK6;D6RBN5;Q9NX40-3;Q9NX40-2;Q9NX40-4;Q9NX40 D6RI08 OCIAD1 OCIA domain-containing protein 1 1 RS(0.5)S(0.5)PPGHYYQK 70.977 0.014155000000000001 65231000.0 39055.0 36142.0 75799.0 88234.0 80365.0 59261.0 64107.0 85866.0 60454.0 66162.0 True False 51473.67760553521 47824.19470466894 74793.85573381328 67893.01450171087 69207.7069508762 55555.400301844646 69812.3988082852 72597.38270438618 63649.47502071291 63845.68851814554 0.8062201035063772 0.7490591113458955 1.1714785676178616 1.0633923147749444 1.083984033333852 0.8701511659014419 1.0934551796468428 1.137075727263139 0.9969267541475904 1.0 15.962301577965965 -5.2497270707295725 24.939658364669103 1.0534803447594119 0.7776395639248542 0.6501037316842178 0.08052343183072821 434.22033879054914 924604.8395170883 0.020810371302126165 0.05407040328794942 5.626948356553369e-06 5.2497270707295725 -0.27584078083455765 RS(ph)SPPGHYYQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSPPGHYYQK 11 1 D6RI08;D6RDK1;D6RIV2;D6R9T5;D6RG39;D6RIT9;D6RDK6;D6RBN5;Q9NX40-3;Q9NX40-2;Q9NX40-4;Q9NX40 D6RI08 OCIAD1 OCIA domain-containing protein 1 1 RS(0.5)S(0.5)PPGHYYQK 79.089 0.0064797 20153000.0 18312.0 23060.0 30771.0 34450.0 43822.0 41493.0 32874.0 39300.0 30013.0 21789.0 True False 21411.859921513806 25349.244401769243 31504.69733966735 32519.878188406954 35235.39367885914 39317.03403574814 29759.936732850696 38268.41664179198 30451.883345982427 25739.173218370914 0.83187831014834 0.9848507637252557 1.2239980310316023 1.263439113312172 1.368940384367531 1.5275173643761895 1.1562118363463993 1.4867772292887218 1.1830948526446021 1.0 14.651678092280047 -5.1406522116263735 1.583561018232825 1.3145496960265954 0.7905117969982617 0.5051479999386939 0.14865844671716094 0.413511495247952 1.5624468662956403 0.04080847460909363 0.27132227177710416 7.233488383869159e-06 5.1406522116263735 -0.5240378990283338 RS(ph)SPPGHYYQK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSPPGHYYQK 11 1 D6RI08;D6RDK1;D6RIV2;D6R9T5;D6RG39;D6RIT9;D6RDK6;D6RBN5;Q9NX40-3;Q9NX40-2;Q9NX40-4;Q9NX40 D6RI08 OCIAD1 OCIA domain-containing protein 1 1 RS(0.5)S(0.5)PPGHYYQK 85.973 0.0040972000000000005 51384000.0 36229.0 18074.0 24854.0 17973.0 18213.0 21576.0 16749.0 15612.0 30841.0 18493.0 True False 35712.36781641508 18032.150763463247 22810.600059214434 19294.79437617041 17141.747148135702 20653.244776112555 17616.181266513584 16337.39051440807 27367.361809872284 21689.490409626414 1.6465286708886857 0.8313773363462732 1.0516890728373425 0.8895918719974549 0.7903250295141884 0.952223606274588 0.8121989467624846 0.7532399427492806 1.261779843279576 1.0 14.404708537117438 -4.757455472615705 24.996444959190384 0.9148920195258919 1.6465297301488175 0.6913337602103008 0.14404537945698628 62.756138755706544 393699.92771296826 0.034222075220532916 0.25403989511675346 1.7480124736134723e-05 4.757455472615705 0.7316377106229256 RS(ph)SPPPPPSGSSSR ddPTM_PC-9_AZD4547_30min_R2 1 RSSPPPPPSGSSSR 14 1 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 RS(0.5)S(0.5)PPPPPSGSSSR 59.225 0.027683 53152000.0 6589.8 4215.7 5263.1 8906.8 7923.9 5493.5 6079.0 5277.2 6755.3 8068.6 True False 8685.219323645018 5578.342582493295 5193.307855151554 6853.474868688247 6823.803261470141 5149.990576571161 6620.019223416562 4461.729997992065 7112.3713667817165 7786.120769890704 1.1154745193821256 0.7164469634307509 0.6669955435618621 0.8802168719487318 0.8764060387886751 0.6614321468639964 0.8502333086094026 0.5730363206342478 0.9134678971697423 1.0 12.926689007047147 RS(ph)SPPPPPSGSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSSPPPPPSGSSSR 14 1 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 RS(0.5)S(0.5)PPPPPSGSSSR;RS(0.859)S(0.141)PPPPPSGSSSR 87.719 0.0027499000000000004 7466900.0 4373.2 6691.0 8759.9 9741.5 7970.2 8560.7 9127.0 8102.599999999999 6973.7 8036.2 True False 5113.496385362833 7355.238260721507 8968.769238105746 9195.715337369122 6408.496524559429 8111.761821748943 8262.424486242271 7889.915335414341 7075.677169555781 9493.099445475804 0.5386540417839834 0.7747983999289976 0.9447672269334604 0.9686736550254502 0.6750689341628644 0.8544903451543241 0.8703611011027548 0.8311211086253285 0.745349525747135 1.0 13.212663480925208 -1.5228787854288304 0.040445407282472805 1.3240208027702043 3.0086557332360977e-06 0.2250213514721292 0.11866347209475978 1471.557444102004 4.547563944310024 40.56491152192013 133.10308423913506 0.029999997226640495 1.5228787854288304 -1.324017794114471 RS(ph)SPPPPPSGSSSR ddPTM_PC-9_Lapatinib_30min_R1 3 RSSPPPPPSGSSSR 14 1 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 RS(0.561)S(0.439)PPPPPSGSSSR;RS(0.78)S(0.22)PPPPPSGSSSR;RS(0.499)S(0.499)PPPPPSGS(0.001)SSR 101.75 0.0023963 62016400.0 34578.7 29369.3 34714.8 28084.0 31612.1 31338.5 26358.4 28441.4 31410.0 21712.1 True False 34085.60139704305 29301.29719029442 31860.6831470032 30149.39104547764 29752.73842977986 29998.22540861158 27723.108979358272 29762.891274435417 27872.275038036667 25465.007555445296 1.3385270482574185 1.1506494599106762 1.2511554562720044 1.1839537443620614 1.1683773650959588 1.1780175341906358 1.088674681089192 1.1687760629810253 1.0945323686768988 1.0 14.636228524831306 -1.522878771902225 0.06643627176436427 0.793450313262063 1.9968254611482985 0.7277652167710955 0.045556722858864175 143.75525174497497 0.7110350128685328 2.374284932330221 16.351333864943836 0.029999998161025224 1.522878771902225 1.2033751478862356 RS(ph)SPSARPPDVPGQQPQAAK ddPTM_PC-9_AZD4547_30min_R2 2 RSSPSARPPDVPGQQPQAAK 20 2 A0A0A6YYC7;Q96JP5-2;Q96JP5 A0A0A6YYC7 ZFP91-CNTF;ZFP91 E3 ubiquitin-protein ligase ZFP91 1 RS(0.442)S(0.442)PS(0.116)ARPPDVPGQQPQAAK;RS(0.483)S(0.483)PS(0.034)ARPPDVPGQQPQAAK 81.696 0.00038546 99347800.0 45099.0 50125.0 62052.0 82197.0 81688.0 66926.0 65569.0 78688.0 57930.0 66712.0 True False 59439.54388252553 66326.92600220045 61229.14993594347 63247.7515809906 70347.03123751836 62741.106640138714 71404.51397601608 66528.57767035559 60992.06153356103 64376.43318555249 0.923312164735854 1.0302982430080592 0.951111251526819 0.9824674721988919 1.0927450894142705 0.9745974347367108 1.1091716400348948 1.0334306263691244 0.9474284068793207 1.0 15.974245025205265 -6.02867857896116 24.774799294997706 1.0302059997513637 0.973170150633303 0.20657365082606505 0.05220151897183383 966.1489002824666 834633.879547634 0.014890975249856964 0.01926550414600183 9.360982234713099e-07 6.02867857896116 -0.0570358491180607 RS(ph)SPSARPPDVPGQQPQAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSSPSARPPDVPGQQPQAAK 20 2 A0A0A6YYC7;Q96JP5-2;Q96JP5 A0A0A6YYC7 ZFP91-CNTF;ZFP91 E3 ubiquitin-protein ligase ZFP91 1 RS(0.552)S(0.446)PS(0.003)ARPPDVPGQQPQAAK;RS(0.494)S(0.494)PS(0.013)ARPPDVPGQQPQAAK 69.525 0.012938 11245800.0 13856.8 12748.400000000001 14398.9 15320.4 17215.2 13355.0 11998.7 14917.9 12659.7 9990.099999999999 True False 16202.482555724788 14013.976900759535 14742.224384132342 14462.047657406963 13842.005140347228 12654.640289866154 10862.096272934703 14526.32093182158 12844.824162700623 11801.226048411912 1.3729490892944256 1.1875017767874543 1.2492112534456705 1.2254699298259029 1.1729294128901075 1.0723157270230483 0.9204209993415398 1.2309162516022123 1.0884313299319563 1.0 13.5266491308381 -6.493483878436077 2.1513309285653124 1.0679846483649686 1.2562988844120184 0.5420781991447192 0.08525226633122668 0.2743384039772354 2.538311834558611 0.031198533178739076 0.03431098457629028 3.210081964327184e-07 6.493483878436077 0.18831423604704978 RS(ph)SPSARPPDVPGQQPQAAK ddPTM_PC-9_Lapatinib_30min_R1 4 RSSPSARPPDVPGQQPQAAK 20 2 A0A0A6YYC7;Q96JP5-2;Q96JP5 A0A0A6YYC7 ZFP91-CNTF;ZFP91 E3 ubiquitin-protein ligase ZFP91 1 RS(0.349)S(0.349)PS(0.301)ARPPDVPGQQPQAAK;RS(0.333)S(0.333)PS(0.333)ARPPDVPGQQPQAAK;RS(0.383)S(0.383)PS(0.234)ARPPDVPGQQPQAAK;RS(0.382)S(0.382)PS(0.237)ARPPDVPGQQPQAAK 59.372 0.021665 247387000.0 88356.5 78084.6 88033.7 78430.0 80155.7 75645.8 62223.4 67162.1 80503.9 56214.4 True False 87096.52010740242 77903.79990620339 80795.90900590918 84198.0038348101 75441.09931816946 72410.60547297254 65445.02319056555 70282.69635330045 71436.7030383508 65930.98413902035 1.321025633771111 1.1815961937097355 1.2254618986961432 1.27706274878701 1.1442434889049484 1.098278850506606 0.9926292477686953 1.0660040536495585 1.08350730648463 1.0 16.00866899589916 -6.628363942441527 2.007889893943744 1.0424292761897405 1.2447618766903368 0.8222290105272769 0.044685450185487564 0.1344895061201962 1.108422675403026 0.016848289037876732 0.016956118661092007 2.3530765594134826e-07 6.628363942441527 0.20233260050059632 RS(ph)SPSSSSTQPQEESR ddPTM_PC-9_AZD4547_30min_R2 1 RSSPSSSSTQPQEESR 16 1 Q4G0A6 Q4G0A6 FAM188B Protein FAM188B 1 RS(0.646)S(0.353)PS(0.001)SSSTQPQEESR 111.09 0.00022801 8251000.0 5446.0 4283.3 5994.8 9012.0 5934.8 8034.5 5270.9 6873.5 5474.8 6684.7 True False 7177.714716162975 5667.792960503247 5915.305035067266 6934.422634012042 5110.8554621048925 7532.101444882318 5739.999888913702 5811.358512316851 5764.186750974278 6450.670687664323 1.1127082847197556 0.8786362279106604 0.9170062031501869 1.0749925038450348 0.792298306574296 1.1676462509992993 0.8898299365816886 0.900892138770929 0.8935794477924885 1.0 12.65523345255676 RS(ph)SPSSSSTQPQEESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSPSSSSTQPQEESR 16 1 Q4G0A6 Q4G0A6 FAM188B Protein FAM188B 1 RS(0.981)S(0.011)PS(0.004)S(0.004)SSTQPQEESR 150.13 1.4115999999999998e-05 8526600.0 3532.4 3386.5 5237.7 3979.3 4278.6 3354.6 3751.5 3809.7 3196.0 2318.0 True False 4130.365551919797 3722.6893394011922 5362.586632087864 3756.352722064665 3440.239044187094 3178.6788705642075 3396.1307614920424 3709.6994117108125 3242.73545376203 2738.2350507220963 1.5084043098603184 1.3595214692834667 1.9584099000827937 1.3718152943349704 1.2563709763629944 1.1608495295997188 1.2402626869437134 1.3547775640124586 1.1842429132980723 1.0 11.41903057784527 -5.9923845904075295 24.911458594930753 1.226072109496837 1.597396195163501 0.5515827057016569 0.16420462512424952 139.46975780885984 456226.14919264003 0.0456514718507739 0.06756256019129865 1.0176897715445027e-06 5.9923845904075295 0.37132408566666397 RS(ph)SPSSSSTQPQEESR ddPTM_PC-9_Lapatinib_30min_R1 2 RSSPSSSSTQPQEESR 16 1 Q4G0A6 Q4G0A6 FAM188B Protein FAM188B 1 RS(0.538)S(0.459)PS(0.003)SSSTQPQEESR;RS(0.5)S(0.5)PS(0.001)SSSTQPQEESR 180.95 4.8698e-06 9233500.0 17539.1 13566.5 18754.0 14732.5 16284.7 16764.9 12036.7 13359.9 15231.3 11260.3 True False 17288.989217722985 13535.08760277328 17212.118512533492 15815.977196179283 15326.865962952033 16047.904307890678 12659.901429974581 13980.649726712803 13515.790601300472 13206.627851593377 1.3091145909466262 1.0248708265933513 1.3032939752638562 1.1975787743781308 1.1605434888591073 1.2151401923508052 0.9586021179848092 1.0586085928836133 1.0234096662055783 1.0 13.688974518894458 -7.254128057650207 24.987269818204886 1.0150391422574865 1.19626876101427 0.5918104089440446 0.07783293330678177 399.12981198345756 1364073.897717598 0.028532100068958937 0.02165135120013838 5.570214793355992e-08 7.254128057650207 0.18122961875678345 RS(ph)SPVPPVPER ddPTM_PC-9_AZD4547_30min_R2 2 RSSPVPPVPER 11 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RS(0.5)S(0.5)PVPPVPER;RS(0.995)S(0.005)PVPPVPER 128.68 0.00043769 210690000.0 110059.0 121303.0 154737.0 218950.0 194798.0 149839.0 138530.0 159977.0 139563.0 176887.0 True False 145055.4726305874 160511.8225405471 152685.08627664027 168474.46024377912 167753.66015823782 140469.54364300452 150858.9016318302 135256.230555745 146940.01525648846 170694.2399702126 0.8497971147468166 0.9403470355447119 0.8944946607646804 0.9869955791898962 0.9827728234269186 0.8229307776730925 0.8837960885976949 0.7923889557102114 0.8608375729733504 1.0 17.38105485027981 -6.767936647763336 24.997803987828213 0.8597528293208773 0.9325032739790935 0.165122803393285 0.06323386730692773 227.8194919454421 876514.9772241601 0.021420568714744036 0.019334372027349517 1.7063312800747163e-07 6.767936647763336 0.07275044465821623 RS(ph)SPVPPVPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSPVPPVPER 11 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RS(0.5)S(0.5)PVPPVPER 96.866 0.0082668 88593000.0 72712.0 80332.0 90339.0 82518.0 94521.0 87076.0 92273.0 98982.0 89276.0 65784.0 True False 85020.70547253762 88306.83006430711 92493.02437256549 77894.78398696544 76000.28857467572 82509.58127146268 83532.23344133155 96383.82738009817 90581.49260640152 77710.11845414239 1.094075098118777 1.1363620571035156 1.1902314166094943 1.0023763383262891 0.977997332735046 1.0617611054106488 1.0749209382639773 1.240299581282653 1.1656331814737186 1.0 16.245814840385727 -10.017897002724641 10.76919420254634 0.9999670982912651 1.1033799975795289 0.1417182287285511 0.07733343445716065 0.0 0.0 0.08343346831483221 0.020235588386686917 9.596281899437449e-11 10.017897002724641 0.1034128992882638 RS(ph)SPVPPVPER ddPTM_PC-9_Lapatinib_30min_R1 3 RSSPVPPVPER 11 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RS(0.5)S(0.5)PVPPVPER;RS(0.5)S(0.5)PVPPVPER;RS(0.5)S(0.5)PVPPVPER 107.93 0.0033034999999999996 180116800.0 157439.0 137788.0 173001.0 144929.0 142690.0 139311.0 115590.0 118087.0 147911.0 107481.0 True False 155193.89098922315 137468.96035166917 158777.5255831724 155587.562128971 134297.25473933358 133352.9932798024 121574.6846137864 123573.75311778816 131251.70560811966 126058.9476405698 1.2311215815613932 1.090513310833219 1.2595498261328713 1.2342444946676516 1.0653528151151441 1.0578621809538664 0.9644272531961054 0.9802854571666929 1.0411930931103432 1.0 16.94373899849235 -6.507886946999443 2.361850480005183 1.002458575493805 1.1993082988518466 0.7706265400199446 0.0500789767307559 0.14532314209099645 1.6240615643724514 0.018142710729025825 0.019670907485680532 3.1053678541274365e-07 6.507886946999443 0.19684972335804174 RS(ph)SPVPPVPERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSPVPPVPERR 12 2 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RS(0.816)S(0.184)PVPPVPERR 51.727 0.031954 6562700.0 12550.0 17391.0 23755.0 17183.0 21987.0 14662.0 17060.0 15813.0 13146.0 12530.0 True False 14674.467126201307 19117.46354688503 24321.409291339176 16220.292218037643 17678.80518500014 13893.098909024147 15443.953296295942 15397.925505258425 13338.235380211398 14801.589812574583 0.9914115518682135 1.2915817685100237 1.64316195755385 1.0958479746721403 1.1943855632305957 0.9386220726925811 1.04339827625649 1.040288624413658 0.901135320536987 1.0 13.853464521048021 -6.420675320411844 1.8871172546854722 0.9922111221803024 1.2963427822429436 0.3801261346759439 0.16380238238882364 0.36360956760606183 2.572048044177419 0.06113568279698875 0.07143870532266021 3.7959866778685985e-07 6.420675320411844 0.30413166006264125 RS(ph)SPVPPVPERR ddPTM_PC-9_Lapatinib_30min_R1 2 RSSPVPPVPERR 12 2 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RS(0.5)S(0.5)PVPPVPERR;RS(0.593)S(0.407)PVPPVPERR 62.338 0.016652 34061000.0 7179.9 4437.0 8530.3 4371.9 6413.9 6717.1 3825.5 4608.3 6793.9 3991.8 True False 7077.5133093675995 4426.726399108467 7828.971661910234 4693.424110230867 6036.647012212571 6429.825291324881 4023.565671684744 4822.4184414262545 6028.699439061358 4681.777311260841 1.511715068622426 0.9455226305747365 1.6722221373237052 1.0024876875160236 1.2893921711510992 1.3733727308771284 0.8594098788097131 1.0300401152842398 1.2876946164356928 1.0 12.192840598953923 -7.245902168509018 24.909897382840327 1.0467894810843428 1.2860800889759374 0.23653963295554792 0.22353256415662176 1185.1572171081398 1900095.6425355887 0.0811771431984407 0.06265206488484926 5.676724679338969e-08 7.245902168509018 0.23929060789159462 RS(ph)SPVYVGR ddPTM_PC-9_AZD4547_30min_R2 1 RSSPVYVGR 9 1 P21980;P21980-2;A2A299;P21980-3 P21980 TGM2 Protein-glutamine gamma-glutamyltransferase 2 1 RS(0.979)S(0.021)PVYVGR 79.23 0.0093737 4920700.0 5954.0 5719.1 7698.3 9041.5 8333.9 7730.5 6010.4 9389.6 7022.0 6605.2 True False 7847.248149106563 7567.687231903934 7596.215512020137 6957.121864782501 7176.881838585292 7247.110612939546 6545.313956312371 7938.653071542923 7393.168584302876 6373.95395846641 1.2311428981508727 1.1872830085086996 1.1917587672452856 1.0914923311520754 1.1259701411950689 1.1369882274272374 1.026884410989249 1.2454832782402123 1.1599030417348186 1.0 12.63797288267147 -14.522878745280336 0.15280458202197936 0.5050001108769059 1.1937466800344503 0.3664906141481631 0.06149715376154547 168.47412043164195 1.5096983090918743 25.8790516419706 0.31284711843185925 3.0000000000000132e-15 14.522878745280336 0.6887465691575444 RS(ph)SPVYVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSSPVYVGR 9 1 P21980;P21980-2;A2A299;P21980-3 P21980 TGM2 Protein-glutamine gamma-glutamyltransferase 2 1 RS(0.891)S(0.109)PVYVGR;RS(0.871)S(0.129)PVYVGR 79.036 0.0095037 35835000.0 19777.9 17402.9 22871.0 23481.3 22779.0 22130.0 25302.0 22102.0 20969.5 17706.5 True False 23125.907838669067 19130.54490024066 23416.33137875051 22165.718888401752 18315.61847041971 20969.463842361518 22905.211389383363 21521.845919004747 21276.13926710352 20916.54828542313 1.1056273493646012 0.9146129007133005 1.119512218709121 1.059721641732311 0.8756520540812165 1.002529841741396 1.0950760649808622 1.0289386960659972 1.017191698016971 1.0 14.352357172703673 -10.698856554354897 14.7789957087925 1.000007553835515 1.0221362004188685 0.008563323961960023 0.07527266877686488 0.0 0.0 0.0724797800095424 0.01757892874711028 2.0005225247167952e-11 10.698856554354897 0.02212864658335345 RS(ph)SPVYVGR ddPTM_PC-9_Lapatinib_30min_R1 1 RSSPVYVGR 9 1 P21980;P21980-2;A2A299;P21980-3 P21980 TGM2 Protein-glutamine gamma-glutamyltransferase 2 1 RS(0.5)S(0.5)PVYVGR 59.418 0.034056 29966000.0 14937.0 12673.0 16516.0 14018.0 14850.0 14411.0 11389.0 10578.0 13545.0 13152.0 True False 14723.995640889683 12643.656447126796 15158.11823360367 15048.930482677159 13976.552196223309 13794.675123681769 11978.666693195011 11069.492496887555 12019.419464826706 15425.305676061578 0.9545350964253335 0.8196697499971359 0.9826786289964708 0.9756001468438636 0.9060794314055909 0.8942886068760133 0.7765594371192669 0.7176190040801733 0.779201379683487 1.0 13.913011458419676 -7.12504092217943 3.607123282659054 0.795115933346434 0.9257988062500533 0.2673229755101535 0.08182682641740952 0.27604589899118304 6.485643678254104 0.032209998715203865 0.02450739269478899 7.498235525294603e-08 7.12504092217943 0.13068287290361924 RS(ph)SQGPTVPPPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSQGPTVPPPPR 13 1 Q8TC26 Q8TC26 TMEM163 Transmembrane protein 163 1 RS(0.5)S(0.5)QGPT(0.001)VPPPPR 79.347 0.006408 3541600.0 10724.0 12507.0 13036.0 14373.0 14036.0 10815.0 13942.0 10928.0 11651.0 9511.7 True False 12539.361391345237 13748.612304116554 13346.827679305308 13567.727407894716 11285.746558269071 10247.84236128061 12621.312828661074 10641.15157917309 11821.37383347353 11236.095915424232 1.1159891732618588 1.22361115529846 1.1878527719742578 1.2075126013537996 1.0044188518163752 0.912046536307419 1.12328275974712 0.947050617872135 1.052089081693034 1.0 13.455853224551484 -6.2653416333903795 24.685890241843165 1.004952164450462 1.1868829351473487 0.6826361244199892 0.05918976726018699 154.3383450339991 976351.8742124041 0.017363986928064148 0.020431053822359293 5.42823157116011e-07 6.2653416333903795 0.18193077069688668 RS(ph)SQPSPTAVPASDSPPTK ddPTM_PC-9_AZD4547_30min_R2 3 RSSQPSPTAVPASDSPPTK 19 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 RS(0.756)S(0.242)QPS(0.002)PTAVPASDSPPTK;RS(0.5)S(0.5)QPS(0.001)PTAVPASDSPPTK;RS(0.512)S(0.368)QPS(0.064)PT(0.055)AVPASDSPPTK 139.78 1.4715e-05 285377000.0 544850.0 554000.0 676640.0 639920.0 599890.0 544240.0 528490.0 692230.0 605210.0 610350.0 True False 718100.9664159745 733069.6659395319 667667.3114912785 492396.3306654445 516605.62835514423 510208.5867649199 575524.5861792114 585261.759362929 637200.1650392968 588981.8322760817 1.2192243072098174 1.2446388424353128 1.1335957662923521 0.836012765899096 0.8771164067298234 0.8662552201198673 0.9771516787795209 0.9936838919143284 1.0818672667319442 1.0 19.167863607831357 -5.584827926965901 5.131733599170065 0.9428002603359791 1.223284000385843 0.7394383459640335 0.06992083574395624 0.10095614026248124 5.263539002637775 0.02116421941068904 0.03793592580930483 2.601189983794062e-06 5.584827926965901 0.28048374004986387 RS(ph)SQPSPTAVPASDSPPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSSQPSPTAVPASDSPPTK 19 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 RS(0.487)S(0.487)QPS(0.019)PT(0.008)AVPASDSPPTK;RS(0.493)S(0.493)QPS(0.014)PTAVPASDSPPTK 122.51 1.469e-05 201851000.0 351309.0 380071.0 361348.0 392828.0 369070.0 285868.0 310775.0 328574.0 301636.0 239633.0 True False 410778.6750309686 417801.93707826646 369963.9067399208 370819.120725559 296753.3828911625 270876.5788381474 281336.14218384353 319949.2806529295 306046.8558607519 283076.5659662153 1.4511221500404747 1.475932617919812 1.3069393627732342 1.3099605029468093 1.048314903348727 0.956902165015228 0.9938517560560649 1.1302570368580596 1.081145148190324 1.0 18.110832797457697 -6.016295168982094 1.6327298327895572 1.0311555397499566 1.4422339806112112 0.894555969619419 0.05990124366298458 0.12121277443666395 0.6509268941714332 0.02226311734755025 0.03707456239300334 9.631741781500295e-07 6.016295168982094 0.41107844086125467 RS(ph)SQPSPTAVPASDSPPTK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSQPSPTAVPASDSPPTK 19 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 RS(0.47)S(0.47)QPS(0.058)PT(0.003)AVPASDSPPTK 139.12 2.6645e-05 92763000.0 462890.0 577240.0 681520.0 602070.0 643180.0 586000.0 528740.0 575030.0 600430.0 613420.0 True False 456289.1037163708 575903.4362455211 625488.0563432793 646348.2362466435 605349.4169405329 560938.1460327189 556115.5700553101 601747.9930502236 532803.2505917979 719448.8296692297 0.634220371066768 0.8004786615752724 0.8693989489577051 0.8983936168800294 0.8414071883595188 0.7796776127784003 0.7729744592273327 0.8364013787149814 0.74057143276855 1.0 19.456532554303436 -4.77515558856138 3.6535647746120006 0.8339061152054316 0.6107732902416303 0.44071880705065514 0.0696282403486109 0.26173635043820537 5.967169264906091 0.017139658836788283 0.1617024240374366 1.6782026843967526e-05 4.77515558856138 -0.22313282496380127 RS(ph)SQPSPTAVPASDSPPTKQEVK ddPTM_PC-9_AZD4547_30min_R2 2 RSSQPSPTAVPASDSPPTKQEVK 23 2 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 RS(0.306)S(0.306)QPS(0.306)PT(0.068)AVPAS(0.011)DS(0.003)PPTKQEVK;RS(0.428)S(0.428)QPS(0.066)PT(0.066)AVPAS(0.009)DS(0.001)PPTKQEVK 45.042 0.01914 18139400.0 81193.0 52766.0 86465.0 144953.0 110282.0 82557.0 63337.0 89964.0 74801.0 105666.0 True False 107010.68508068673 69821.5776046307 85318.41760477271 111536.32535152543 94971.24790588596 77394.69773914356 68973.87029997283 76062.13096705808 78754.82815073185 101966.66550222744 1.0494673386995195 0.6847490526509908 0.8367285248031274 1.09385086588998 0.9313950538454289 0.7590196007483729 0.6764354797741827 0.7459509496796923 0.7723585719198738 1.0 16.637738064136478 -6.764197058127021 24.96104691457357 0.7677299937971315 0.9113278397972053 0.18166938675586797 0.13136154235641892 115.28637626346614 1043502.4910122565 0.04592515463280034 0.042311578652334245 1.7210874662158928e-07 6.764197058127021 0.14359784600007386 RS(ph)SQPSPTAVPASDSPPTKQEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSSQPSPTAVPASDSPPTKQEVK 23 2 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 RS(0.499)S(0.499)QPS(0.001)PTAVPASDSPPTKQEVK;RS(0.651)S(0.343)QPS(0.005)PTAVPASDSPPTKQEVK 130.51 2.3133e-06 32074100.0 140545.0 82365.0 96492.0 162903.0 157671.0 154748.0 141701.0 199102.0 150486.0 108327.0 True False 164336.4926097179 90541.65286867847 98792.7352279476 153776.07304865174 126776.4994007438 146632.74246171513 128278.0554536006 193875.78346600663 152686.57305845825 127965.8275839396 1.2842216997496527 0.7075455578895654 0.7720243528542352 1.201696389981785 0.9907058923022583 1.1458742168141014 1.0024399316251535 1.5150590366700296 1.1931823983110101 1.0 16.96539907405844 -6.746943426957732 0.9891214443150282 1.2298586859936171 0.9380606644722197 0.15301524961100832 0.20923553041564705 0.8133804666802033 1.712049961181907 0.119915958875688 0.11102370664594406 1.7908391211456503e-07 6.746943426957732 -0.29179802152139744 RS(ph)SQPSPTAVPASDSPPTKQEVK ddPTM_PC-9_Lapatinib_30min_R1 2 RSSQPSPTAVPASDSPPTKQEVK 23 2 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 RS(0.386)S(0.386)QPS(0.208)PT(0.017)AVPAS(0.003)DSPPTKQEVK;RS(0.795)S(0.173)QPS(0.026)PT(0.007)AVPASDSPPTKQEVK 103.9 9.1071e-07 41416000.0 306268.0 137734.0 184908.0 152551.0 122823.0 136087.0 94386.0 96645.0 167792.0 111366.0 True False 301900.562157328 137415.08538535165 169705.57800552118 163770.1094352179 115598.79261930885 130266.8762442914 99272.84524575506 101135.47951991846 148893.49803190856 130615.46471413238 2.311369199796315 1.0520583124372067 1.2992763022123162 1.2538339912019487 0.8850314384465169 0.9973311853186458 0.7600389851464036 0.7742994272635755 1.139937742883508 1.0 16.99496619479394 -2.5676543241925818 1.1166816479672637 0.9682793526279021 199.9999997522548 0.8161907061246806 0.18193013232843322 101.39726462020236 1.098645783051757 0.0576075348273354 50627.25951569597 0.002706111431006778 2.5676543241925818 199.03172039962692 up RS(ph)SSSGDQSSDSLNSPTLLAL ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSSSGDQSSDSLNSPTLLAL 21 1 P15408;P15408-3;P15408-2 P15408 FOSL2 Fos-related antigen 2 1 RS(0.4)S(0.4)S(0.146)S(0.047)GDQS(0.003)S(0.003)DS(0.001)LNSPTLLAL 77.357 0.0017992999999999998 5434300.0 6990.1 5480.5 7864.6 10109.0 9144.9 7250.6 8932.3 7831.7 7972.7 6080.8 True False 8173.385869231855 6024.567820637303 8052.121890661588 9542.625503820196 7353.022492213936 6870.36577204819 8086.1678797482 7626.126173372068 8089.285654633463 7183.200904413685 1.1378473159799494 0.838702397553093 1.1209657084370281 1.328464236320715 1.0236414921509303 0.956449062677159 1.1257053766628873 1.0616612670106762 1.1261394136509586 1.0 12.810411150976991 -7.128425158288831 0.002339273510328162 0.40759029863756946 1.7364401822200306 0.00451274222973741 0.12370861414987332 1060538.8974706286 1294.6086563060887 366067.9343541141 369323.33201226505 7.440032655033565e-08 7.128425158288831 1.3288498835824611 RS(ph)STS(ph)GDTEEEEEEEVVPFSSDEQK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSTSGDTEEEEEEEVVPFSSDEQK 25 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 2 RS(0.464)S(0.432)T(0.228)S(0.477)GDT(0.385)EEEEEEEVVPFS(0.007)S(0.007)DEQK 45.325 0.035611000000000004 1757500.0 4759.3 6557.7 4153.8 4498.7 7295.3 5480.3 5082.5 6110.7 4914.2 5624.8 True False 4691.431509251271 6542.51604855389 3812.290598131686 4829.54940522327 6866.204797111643 5245.920344203264 5345.646981136508 6394.6254302071075 4360.711047179875 6597.03918542512 0.711141980119821 0.9917352110031894 0.5778790289065135 0.7320783262729776 1.0408009720908118 0.7951931460090624 0.810310024070598 0.9693174847793528 0.6610103297270117 1.0 12.687602958994132 RS(ph)STSGDT(ph)EEEEEEEVVPFSSDEQKR ddPTM_PC-9_AZD4547_30min_R2 1 RSSTSGDTEEEEEEEVVPFSSDEQKR 26 2 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 2 RS(0.256)S(0.256)T(0.256)S(0.256)GDT(0.976)EEEEEEEVVPFSSDEQKR 70.12100000000001 0.00030925 2917700.0 10412.0 6962.6 7855.2 13105.0 15202.0 10138.0 10354.0 10517.0 8701.8 11714.0 True False 13722.799416946176 9213.124288936084 7751.034915503496 10083.844720231675 13091.464705620841 9504.069257354775 11275.485941644201 8891.839306617634 9161.759382923208 11303.89642546411 1.2139884249145314 0.815039694470468 0.6856958542226963 0.8920680392573268 1.158137354844291 0.8407781617624439 0.9974866645313638 0.7866171956943206 0.8104956944124733 1.0 13.464532531371283 -7.763293714912902 24.99994402242763 0.8489173492081684 0.9308192925897326 0.041466036115690996 0.15734859412067764 178.64595911456612 2408343.9302863 0.08276177051982381 0.04293732235750893 1.7246710962438274e-08 7.763293714912902 0.0819019433815642 RS(ph)STSGDT(ph)EEEEEEEVVPFSSDEQKR ddPTM_PC-9_Lapatinib_30min_R1 1 RSSTSGDTEEEEEEEVVPFSSDEQKR 26 2 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 2 RS(0.297)S(0.297)T(0.308)S(0.308)GDT(0.789)EEEEEEEVVPFSSDEQKR 87.208 1.1644e-06 4051600.0 9544.0 7637.7 8788.6 7439.5 8683.5 7672.2 8468.8 7909.3 10991.0 9360.4 True False 9407.900809844752 7620.015374908894 8066.035232977073 7986.625647444485 8172.753602417857 7344.077890771723 8907.273025843351 8276.794952319227 9753.077839638998 10978.332668051 0.8569516969752158 0.6940958709590358 0.7347231566821384 0.7274898556032154 0.7444439742841914 0.668961135796546 0.8113502564706552 0.753920946156628 0.88839335940532 1.0 13.422371341525638 -8.477019961842903 1.441986266435903 1.0012171225663296 0.7396983377563902 0.7198416291732515 0.05100787850881407 0.20434348480761336 0.9313386566783127 0.045964903302490145 0.013752152725952274 3.3341108755652014e-09 8.477019961842903 -0.2615187848099394 RS(ph)STSGDTEEEEEEEVVPFSSDEQK ddPTM_PC-9_AZD4547_30min_R2 3 RSSTSGDTEEEEEEEVVPFSSDEQK 25 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RS(0.241)S(0.241)T(0.241)S(0.241)GDT(0.035)EEEEEEEVVPFSSDEQK;RS(0.213)S(0.211)T(0.211)S(0.211)GDT(0.154)EEEEEEEVVPFSSDEQK;RS(0.218)S(0.218)T(0.218)S(0.218)GDT(0.129)EEEEEEEVVPFSSDEQK 116.45 3.6075000000000002e-09 115837000.0 253133.0 197836.0 236896.0 248813.0 277518.0 278728.0 206216.0 251493.0 208217.0 252048.0 True False 333624.0285065157 261782.61810616133 233754.60425490342 191453.00697252998 238989.41600937332 261299.09409784776 224568.82450667382 212630.53558421484 219222.92553656982 243223.87623743984 1.3716746631437842 1.076303125152911 0.9610676709498194 0.787147256816308 0.982590277346239 1.0743151459471132 0.9233009027758665 0.8742173625118975 0.9013215681282876 1.0 17.891925333311157 -4.781453075132409 2.05279921427027 0.9340058608408729 1.4973888639747368 0.7656874298305082 0.07306277058873936 0.36005360476591036 1.685886396567344 0.021020017411152322 0.3853881802916026 1.654043492035881e-05 4.781453075132409 0.5633830031338639 RS(ph)STSGDTEEEEEEEVVPFSSDEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSTSGDTEEEEEEEVVPFSSDEQK 25 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RS(0.242)S(0.242)T(0.242)S(0.242)GDT(0.033)EEEEEEEVVPFSSDEQK 101.05 6.377399999999999e-07 39128000.0 76070.0 71772.0 54231.0 90330.0 88453.0 77193.0 82530.0 85201.0 67041.0 55423.0 True False 88947.14854901462 78897.04983537665 55524.07271221278 85269.10295381132 71121.26961517341 73144.86318948987 74712.16093454296 82964.5640279217 68021.34779588883 65470.75117177336 1.3585784026770527 1.2050732338227979 0.8480744717062461 1.3023999484914066 1.0863059968347542 1.1172143572567574 1.1411532569486371 1.2672004298568444 1.0389578029649233 1.0 15.99856291118056 -4.90468460888707 4.597307657246898 1.1133142811371926 1.3480429631756647 0.291089387021386 0.12284532204629223 0.26553500557597065 9.251492478264431 0.029559633504486284 0.1403411726767688 1.245418725045246e-05 4.90468460888707 0.2347286820384722 RS(ph)STSGDTEEEEEEEVVPFSSDEQK ddPTM_PC-9_Lapatinib_30min_R1 2 RSSTSGDTEEEEEEEVVPFSSDEQK 25 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RS(0.226)S(0.226)T(0.226)S(0.226)GDT(0.097)EEEEEEEVVPFSSDEQK;RS(0.308)S(0.218)T(0.218)S(0.218)GDT(0.039)EEEEEEEVVPFSSDEQK 90.475 2.6889999999999996e-06 43735600.0 56768.0 48602.0 51320.0 44095.0 49867.0 45938.0 39644.0 38656.3 46427.0 40761.0 True False 55958.47791002378 48489.46505509798 47100.66770092885 47337.89339660789 46933.921102294116 43973.338826708314 41696.572340418235 40452.41281976126 41197.90236201616 47806.48453938151 1.1705206615626988 1.0142863572232308 0.9852359602415184 0.9901981677320865 0.9817480108505238 0.9198195443650418 0.8721949070752082 0.846169995755237 0.8617638958179114 1.0 15.544918700230417 -1.5228789008241614 0.40557641849191906 0.8896510675576997 5.380663639255833 0.7154175983263538 0.048496316703322606 39.82686258413651 0.5235154262386523 0.035669339969481115 143.54621287334035 0.029999989255415218 1.5228789008241614 4.491012571698134 RS(ph)STSGDTEEEEEEEVVPFSSDEQKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RSSTSGDTEEEEEEEVVPFSSDEQKR 26 2 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RS(0.301)S(0.301)T(0.301)S(0.076)GDT(0.02)EEEEEEEVVPFSSDEQKR;RS(0.394)S(0.394)T(0.106)S(0.106)GDT(0.001)EEEEEEEVVPFSSDEQKR;RS(0.219)S(0.219)T(0.219)S(0.219)GDT(0.124)EEEEEEEVVPFSSDEQKR 96.881 1.2603e-09 60238000.0 88785.0 81552.0 95308.0 100845.0 117059.0 102291.0 112479.0 114537.0 95384.0 85624.0 True False 103814.5469163174 89647.94360160835 97580.50417760291 95194.9815939011 94122.12926506266 96926.67988698593 101824.17484255989 111530.52511198266 96778.8105512009 101146.95340078893 1.0263734440419405 0.8863138294080255 0.9647399244043053 0.9411552043164021 0.9305483368550823 0.958275821743435 1.0066954210581855 1.1026582745408993 0.9568138959926997 1.0 16.626093340257206 -7.291689069795048 3.7470255077035994 1.0271791876504728 0.946813773021408 0.31166660623787046 0.0470879684216004 0.23621684776377277 7.232952530278786 0.019229114302993663 0.013061080501336534 5.1087062345393764e-08 7.291689069795048 -0.08036541462906477 RS(ph)STSGDTEEEEEEEVVPFSSDEQKR ddPTM_PC-9_Lapatinib_30min_R1 1 RSSTSGDTEEEEEEEVVPFSSDEQKR 26 2 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RS(0.416)S(0.416)T(0.083)S(0.083)GDT(0.004)EEEEEEEVVPFSSDEQKR 102.61 5.1262e-10 24713000.0 48848.0 31565.0 44036.0 46257.0 43088.0 43419.0 36016.0 38300.0 50683.0 38145.0 True False 48151.41856237388 31491.913181847824 40415.53006387571 49658.89408882846 40553.64855426737 41562.070584632515 37880.73225235857 40079.55782102416 44974.54682434932 44738.31242498242 1.076290453358396 0.7039137480800987 0.9033762757959369 1.1099858576940496 0.9064635288214787 0.9290039863332831 0.8467179515516439 0.8958665548288148 1.00528036008875 1.0 15.449223217036618 -8.269717595531318 23.2434642804656 1.0026402343457017 0.917143880287175 0.08368402717912271 0.10670215924380623 671.3609064711687 1884976.2010754566 0.0959874156535589 0.02666148212449426 5.373811204013621e-09 8.269717595531318 -0.08549635405852674 RS(ph)STSSEPTPTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSTSSEPTPTVK 13 1 Q69YQ0-2;Q69YQ0;F8WAN1;A0A494C1J1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 RS(0.499)S(0.499)T(0.002)SSEPTPTVK 91.712 0.007313200000000001 16612000.0 24258.0 23963.0 20611.0 26380.0 29771.0 29175.0 30147.0 25689.0 22361.0 22270.0 True False 28364.400282660637 26341.888274050143 21102.444407652787 24902.014125113943 23937.586262911685 27645.011640347802 27291.25791462096 25014.690969745385 22687.987322144167 26307.37471077701 1.078191974474783 1.0013119349099853 0.8021493835722048 0.9465792158619556 0.9099192346663719 1.0508464620387536 1.0373995206538376 0.9508623055229426 0.8624192862866649 1.0 14.68317966451395 -6.688798155856152 24.999999706104862 0.9808196299370169 0.9424721736457674 0.03696263360703511 0.08126390161041626 166.5048469990124 57299.80989265848 0.028612166882561976 0.02861216077138971 2.0473959701768678e-07 6.688798155856152 -0.03834745629124947 RS(ph)STVAPAQPDGAESEWTDVETR ddPTM_PC-9_AZD4547_30min_R2 2 RSSTVAPAQPDGAESEWTDVETR 23 1 Q02241;H7BYN4;A0A2U3TZL8;Q02241-2;Q02241-3 Q02241;Q02241-2 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 RS(0.74)S(0.153)T(0.107)VAPAQPDGAESEWTDVETR;RS(0.785)S(0.108)T(0.108)VAPAQPDGAESEWTDVETR 149.71 4.1984e-09 57897000.0 19562.5 19271.6 26121.0 38081.0 35387.8 23268.2 21099.2 27858.3 23418.3 22742.1 True False 25782.968074722387 25500.76782332184 25774.618472841797 29302.013795585066 30474.81480789169 21813.235775693665 22976.9879254336 23553.439855048586 24656.14352859299 21945.906001156505 1.1748418166633756 1.1619829148078007 1.174461353816221 1.3351927140324444 1.388633251517879 0.9939546708413018 1.046982882557811 1.073249828638078 1.1234962697504338 1.0 14.421664210302701 -6.778589335884031 24.999999632840645 1.05208020716193 1.2431652027564406 0.6342239531591971 0.07567977713663374 185.72525396146895 270735.40539286734 0.029574083719635946 0.02614550074953437 1.6649862990892775e-07 6.778589335884031 0.19108499559451064 RS(ph)STVAPAQPDGAESEWTDVETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSSTVAPAQPDGAESEWTDVETR 23 1 Q02241;H7BYN4;A0A2U3TZL8;Q02241-2;Q02241-3 Q02241;Q02241-2 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 RS(0.726)S(0.137)T(0.137)VAPAQPDGAESEWTDVETR;RS(0.746)S(0.186)T(0.068)VAPAQPDGAESEWTDVETR 120.33 7.2301000000000005e-09 36663000.0 16594.9 14017.3 16762.4 14570.699999999999 20006.5 17279.5 16249.9 22096.3 14811.8 18267.6 True False 19404.08880578471 15408.844906891574 17162.079187756008 13754.350917846758 16086.369942861922 16373.332601178743 14710.591832912032 21516.29553796509 15028.394553827415 21579.371273757963 0.8991962073233084 0.7140543953488495 0.7953002416074237 0.6373842288247303 0.7454512802430014 0.7587492885434466 0.681696961709035 0.9970770355172683 0.6964241155673985 1.0 14.397365211314899 -9.263347636187165 0.5431153738475629 1.0114770579147672 0.7495980612496732 0.3031671076044784 0.10270499668829651 3.2075622014851333 1.3961724667724082 0.1986231801000527 0.04584378416405207 5.453211775131595e-10 9.263347636187165 -0.26187899666509395 RS(ph)STVAPAQPDGAESEWTDVETR ddPTM_PC-9_Lapatinib_30min_R1 2 RSSTVAPAQPDGAESEWTDVETR 23 1 Q02241;H7BYN4;A0A2U3TZL8;Q02241-2;Q02241-3 Q02241;Q02241-2 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 RS(0.742)S(0.129)T(0.129)VAPAQPDGAESEWTDVETR;RS(0.823)S(0.088)T(0.088)VAPAQPDGAESEWTDVETR 189.11 8.1309e-21 36906000.0 14148.9 12734.2 13194.199999999999 8397.4 17762.4 18156.1 18417.1 13626.0 19249.9 20786.8 True False 13947.134091409524 12704.714742286915 12109.423807084859 9014.97280890521 16717.65055422202 17379.605926936285 19370.647322437602 14259.11370415862 17081.773551566443 24379.770683330036 0.5720781492397731 0.5211170731385886 0.49669965990963255 0.3697726662814473 0.6857181214445514 0.7128699507752057 0.7945377162912577 0.5848748082732568 0.7006535776501914 1.0 14.573396935549475 -6.41567672868625 5.781110885878895 0.7313168083209908 0.49344801866969773 0.5660635708208942 0.110180233804005 0.18685104655129897 8.520464313350619 0.03363487383958472 0.03806191764359174 3.839929680324841e-07 6.41567672868625 -0.23786878965129304 RS(ph)SYLLAITTER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSYLLAITTER 12 1 Q9P227;Q9P227-2 Q9P227 ARHGAP23 Rho GTPase-activating protein 23 1 RS(0.5)S(0.5)YLLAITTER 99.915 0.0014655 5725600.0 10337.0 10496.0 10729.0 15389.0 18322.0 13670.0 11304.0 13548.0 11297.0 10345.0 True False 12086.849934943659 11537.973514352552 10984.820049959082 14526.804221811157 14731.935625577496 12953.121135340349 10233.203286127164 13192.37935529256 11462.197253175742 12220.466609025061 0.9890661561169257 0.9441516337708027 0.8988871212042403 1.1887274591530588 1.2055133487863439 1.0599530729681146 0.8373823695545092 1.0795315577843583 0.9379508671715266 1.0 13.57701175158617 -10.6894921025096 14.528390978549831 0.9999999001089953 1.0187540389029532 0.001054775463144142 0.11375459235891945 0.0 0.0 0.11821781693502871 0.028672032120767982 2.044127107387462e-11 10.6894921025096 0.01875413879395793 RS(ph)TQGVTLTDLK ddPTM_PC-9_AZD4547_30min_R2 1 RSTQGVTLTDLK 12 1 Q9BZL4-3;K7EL81;K7ER83;Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-3;Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 RS(0.5)T(0.5)QGVTLTDLK 130.56 6.5199e-05 6543900.0 28925.0 23380.0 43084.0 32919.0 38645.0 28330.0 42134.0 32554.0 28175.0 24822.0 True False 38122.54832262467 30937.127779181003 42512.67800941446 25330.03314348006 33279.80881125627 26558.52062150926 45883.84437562653 27523.52731649998 29664.272979597503 23952.989335228798 1.591557019839525 1.2915769028327626 1.7748380970090047 1.0574894343657548 1.3893801873952356 1.1087768733086012 1.9155790424931634 1.149064399908525 1.2384371973133579 1.0 14.547918095218058 -13.423795332599386 0.14921425684332076 2.8523857655744382e-08 1.5278611687272174 0.19299430346219681 0.26690156422825834 163.10687434491877 1.9598011374395996 50.46249761263998 1.4151076718287756 3.768813678004597e-14 13.423795332599386 1.5278611402033597 RS(ph)TQGVTLTDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSTQGVTLTDLK 12 1 Q9BZL4-3;K7EL81;K7ER83;Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-3;Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 RS(0.962)T(0.038)QGVTLTDLK;RS(0.5)T(0.5)QGVTLTDLK 160.63 3.5437e-05 12881300.0 60275.0 93629.0 65285.0 98807.0 61136.0 74562.0 78192.0 71840.0 55264.0 54024.0 True False 70478.36701448471 102923.86834749591 66841.64199474124 93271.16412661606 49156.83966844808 70651.83746110069 70785.08769894336 69954.27612077199 56072.131450783745 63818.12354625131 1.1043628846812847 1.6127686404458954 1.0473771129653895 1.4615153022952652 0.770264572771751 1.107081085044701 1.109169053641053 1.096150626711448 0.8786239446565087 1.0 15.96167856901411 -6.250944363210524 24.977593956771855 1.0098134256766869 1.3098726790856274 0.41625367763431786 0.18093009852842312 711.2811139318192 1692811.05764412 0.05073410366617732 0.06480934866127248 5.611198556186983e-07 6.250944363210524 0.3000592534089406 RS(ph)TQGVTLTDLK ddPTM_PC-9_Lapatinib_30min_R1 1 RSTQGVTLTDLK 12 1 Q9BZL4-3;K7EL81;K7ER83;Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-3;Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 RS(0.5)T(0.5)QGVTLTDLK 112.64 0.00042578 9549500.0 32481.0 57773.0 37104.0 32963.0 34335.0 35813.0 55903.0 24464.0 34344.0 26344.0 True False 32017.814983714128 57639.23016806253 34053.45234558192 35387.208981344505 32315.482805207223 34281.36147418053 58797.383804520265 25600.68675022284 30475.81706164695 30897.525298826502 1.036258233436261 1.8654966574378593 1.1021417416518884 1.1453088439639054 1.045892267832679 1.1095180323546023 1.9029803596197203 0.8285675471619458 0.9863513911518484 1.0 14.915203671333341 -6.899365468928344 0.159021220071407 0.8671787223740419 1.5633220835884796 0.07613639204242384 0.33736386745556285 22.126304072268983 1.7647107181778157 2.3260584322595137 4.597796840002786 1.2607661239752328e-07 6.899365468928344 0.6961433612144377 RS(ph)TQGVTLTDLQEAEK ddPTM_PC-9_AZD4547_30min_R2 2 RSTQGVTLTDLQEAEK 16 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 RS(0.5)T(0.5)QGVTLTDLQEAEK;RS(0.5)T(0.5)QGVTLTDLQEAEK 188.34 1.8909e-08 52095000.0 196300.0 147264.0 259760.0 253740.0 236500.0 189716.0 246320.0 175503.0 181194.0 202569.0 True False 258719.31670635182 194864.20809552242 256315.41267583112 195244.16324392083 203666.05728715463 177853.02852913024 268242.00281493174 148383.0440077317 190771.5449251176 195477.12096720477 1.3235273541283494 0.9968645288581615 1.311229730659033 0.9988082609252107 1.041892044856358 0.9098406383781797 1.3722424470326364 0.7590813864740004 0.9759277401938172 1.0 17.57664023594024 -1.5228787453654327 0.2645364257335718 0.9598932354222258 2.964703283013269 0.20810014862307225 0.1690986104137265 85.32771487807298 1.1842260942923266 0.19756696623824915 77.56427036358676 0.02999999999412184 1.5228787453654327 2.004810047591043 RS(ph)TQGVTLTDLQEAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RSTQGVTLTDLQEAEK 16 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 RS(0.461)T(0.461)QGVT(0.077)LT(0.002)DLQEAEK;RS(0.494)T(0.494)QGVT(0.01)LT(0.001)DLQEAEK;RS(0.5)T(0.5)QGVTLTDLQEAEK 120.54 4.1343999999999996e-05 26274000.0 186419.0 196039.0 156484.0 260817.0 168541.0 198602.0 229597.0 181696.0 169394.0 174295.0 True False 217976.05475691767 215500.4563433837 160215.17202887492 246204.26907012283 135516.60093169153 188186.9615011605 207847.91002166775 176926.6725228252 171871.0667880367 205893.3037815396 1.0586845261767148 1.0466608305631815 0.7781465889676 1.1957857033143469 0.6581884813285606 0.914002340264712 1.009493296791245 0.8593124170300891 0.834757923795318 1.0 17.651537384745694 -5.1185803974524156 10.135131861935516 0.906677647902395 1.0556265923735515 0.1541747643402811 0.13733633320638217 0.6645888207226351 52.32462656981015 0.03331388187790956 0.08845859287998036 7.610612368044807e-06 5.1185803974524156 0.14894894447115647 RS(ph)TQGVTLTDLQEAEK ddPTM_PC-9_Lapatinib_30min_R1 3 RSTQGVTLTDLQEAEK 16 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 RS(0.5)T(0.5)QGVTLTDLQEAEK;RS(0.5)T(0.5)QGVTLTDLQEAEK;RS(0.499)T(0.499)QGVT(0.003)LTDLQEAEK 161.31 1.8579e-05 78302000.0 469240.0 541310.0 387231.0 316286.0 386295.0 379440.0 505110.0 308150.0 308482.0 195328.0 True False 462548.55155192304 540056.6299529877 355394.3619348863 339546.7275391657 363573.88758519077 363212.23571784154 531262.1242777893 322467.77395688207 273737.50870052906 229090.18454179986 2.0190675234605098 2.3573975071570508 1.551329502159622 1.4821531014883438 1.5870338937146955 1.5854552496183867 2.3190086704952435 1.4076018778449433 1.1948897297718264 1.0 17.805556121572522 -1.5228789388957054 0.05755346968910916 1.3334607510266104e-09 5.055551457526888 0.4423192111335934 0.31846607153429746 401.04634477652166 1.735679897335409 32.09588333604319 172.12037748147813 0.029999986625527192 1.5228789388957054 5.055551456193427 RS(ph)TSPIIGS(ph)PPVR ddPTM_PC-9_Lapatinib_30min_R1 1 RSTSPIIGSPPVR 13 1 Q86TB9-4;Q86TB9;Q86TB9-2 Q86TB9-4 PATL1 Protein PAT1 homolog 1 2 RS(0.756)T(0.135)S(0.12)PIIGS(0.99)PPVR 67.64399999999999 0.02615 5474200.0 15418.0 8015.1 12410.0 14247.0 17399.0 14330.0 14451.0 13123.0 18876.0 13377.0 True False 15198.136492685087 7996.541528396272 11389.69770398532 15294.771906598779 16375.625027750131 13717.139304861556 15199.202070713947 13732.74248786684 16749.986106908 15689.19662626791 0.9687007470630677 0.5096845758824848 0.7259579935989787 0.9748601073041077 1.0437516603197488 0.8743047608884827 0.9687686650103179 0.8752992785414236 1.0676127341577224 1.0 13.937483859773053 -5.750024370534994 7.79491483465686 0.9658500316874252 0.7113057843074491 0.4515901000025353 0.11888274642329022 0.11631272670194026 41.82903585329892 0.03111261818358379 0.05144261541061232 1.7781796242795613e-06 5.750024370534994 -0.25454424737997616 RS(ph)TSTLYSQFQTAESENR ddPTM_PC-9_AZD4547_30min_R2 1 RSTSTLYSQFQTAESENR 18 1 O95248;O95248-5;O95248-4;H0Y5W8 O95248 SBF1 Myotubularin-related protein 5 1 RS(0.674)T(0.134)S(0.134)T(0.044)LY(0.013)SQFQTAESENR 105.38 0.00015763 3030300.0 5683.2 4181.1 8837.3 6669.8 7570.6 5801.6 7346.7 8553.3 5150.8 4969.5 True False 7490.339382096475 5532.558809133174 8720.111627810753 5132.180657382767 6519.552868068226 5438.825034865795 8000.542067556259 7231.584020280745 5423.060772433387 4795.519317598077 1.5619454090424034 1.1536933630588015 1.8183873424950314 1.0702033121937904 1.359509249424453 1.1341472475998553 1.6683369490759297 1.507987673773529 1.1308599576551441 1.0 12.227471341063936 -8.440944509693134 4.434934225390733 1.0032902043396577 1.3997970613173076 0.27076897604772066 0.22973207438374818 0.2639304081198243 8.841731999919226 0.2125634507496453 0.055563415532399116 3.6228928557943487e-09 8.440944509693134 0.39650685697765 RS(ph)TVLGLPQHVQK ddPTM_PC-9_AZD4547_30min_R2 1 RSTVLGLPQHVQK 13 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 RS(0.788)T(0.212)VLGLPQHVQK 114.87 0.00010935 40675000.0 67119.0 66605.0 91926.0 136840.0 119580.0 100500.0 95625.0 126420.0 98044.0 128580.0 True False 88461.44583807241 88133.76371823571 90707.00117661868 105293.65215692505 102978.38110104864 94215.71911266072 104135.43974982869 106884.69384259782 103226.405679207 124078.4533367062 0.712947683172827 0.7103067563154662 0.7310455501123237 0.848605453448024 0.8299457184689494 0.75932377120298 0.8392709366487746 0.8614283219065405 0.8319446519782616 1.0 16.920893082546833 -10.367886178857194 0.0362010401534972 1.8867431544404707 6.752587570147398e-13 0.8171331056668122 0.035795829825871636 158.77170291227648 1.1689365107482093 36.85635846309058 24.648891377805427 4.2866085034141574e-11 10.367886178857194 -1.8867431544397955 RS(ph)TVLGLPQHVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSTVLGLPQHVQK 13 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 RS(0.5)T(0.5)VLGLPQHVQK 109.14 0.00037581 32123000.0 100200.0 86945.0 101130.0 100690.0 128930.0 94375.0 95085.0 94715.0 71182.0 71183.0 True False 117161.8809597902 95576.32500051262 103541.32273766056 95048.66574138466 103667.0920317493 89425.80886230755 86077.86044421469 92228.83160883775 72222.90208688637 84087.91441568207 1.3933260418448428 1.1366238021796864 1.2313460674718615 1.1303487118436422 1.232841755585459 1.0634799243591417 1.0236650658107118 1.0968143549489369 0.8588975310989172 1.0 16.359610842747017 -6.539995090766204 0.433945604870146 0.9456443561121585 1.316407650319365 0.6521786542165098 0.08250417183713428 0.907580895056341 0.33898026784081986 0.07631040780503849 0.14369112437260897 2.8840641041969347e-07 6.539995090766204 0.37076329420720644 RS(ph)TVLGLPQHVQK ddPTM_PC-9_Lapatinib_30min_R1 1 RSTVLGLPQHVQK 13 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 RS(0.5)T(0.5)VLGLPQHVQK 92.781 0.0016312000000000002 40957000.0 159090.0 107490.0 112520.0 121590.0 85221.0 106380.0 79430.0 68412.0 120590.0 68823.0 True False 156821.34742646734 107241.11350916597 103269.03993976065 130532.13421234972 80208.46833093252 101830.37538389186 83542.49674602505 71590.67127028486 107007.88433100432 80718.96384911677 1.9428067451361777 1.3285739607563039 1.2793652819032144 1.6171185553910947 0.9936756433204657 1.2615421522783348 1.0349797961007792 0.8869126640934726 1.3256845631842833 1.0 16.30062003492366 -1.5228787452803931 0.4035421127892099 1.0593591394279407 13.862509457666993 0.606369107478694 0.19143524548737942 51.43044786393394 0.6783194974062788 0.13485986915029627 524.9722058017152 0.02999999999999616 1.5228787452803931 12.803150318239053 RS(ph)WGQQAQEYQEQK ddPTM_PC-9_AZD4547_30min_R2 2 RSWGQQAQEYQEQK 14 1 Q5VZK9-2;Q5VZK9 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 RS(1)WGQQAQEYQEQK;RS(1)WGQQAQEYQEQK 148.36 0.00024395 21975000.0 42804.0 48424.0 70176.0 90851.0 84001.0 80251.0 69399.0 83234.0 66671.0 80842.0 True False 56414.781621491 64076.11101706847 69245.42038781614 69906.7055839579 72338.91111280464 75232.89228368306 75575.37655632294 70372.09782704299 70195.0929484558 78011.74618638954 0.7231575292097936 0.8213649116887428 0.8876281300302077 0.8961048688351793 0.927282295924628 0.9643790321515544 0.9687691950357641 0.9020705376714229 0.8998015860424684 1.0 16.25140374569103 -4.0102609925376465 0.6679083942430244 0.9432948584436143 0.23914620045232968 0.8506371730392706 0.029239210636023315 3.007801971377777 0.47767505047057207 0.01294712492719797 2.0376804953736176 9.766501193218776e-05 4.0102609925376465 -0.7041486579912846 RS(ph)WGQQAQEYQEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSWGQQAQEYQEQK 14 1 Q5VZK9-2;Q5VZK9 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 RS(1)WGQQAQEYQEQK 147.49 2.0160999999999998e-08 0.0 10817.0 9675.4 12395.0 13695.0 18819.0 17037.0 15984.0 14593.0 13870.0 12121.0 True False 12648.104454511513 10635.909769509024 12690.543808299271 12927.71354978905 15131.55204332185 16143.549728075603 14469.879805861325 14209.949212561574 14072.822510537966 14318.441350216799 0.8833436646594223 0.7428119799749002 0.8863076292942402 0.9028715649691375 1.056787653992293 1.1274655762605872 1.0105764623355622 0.9924229086810777 0.982845979274475 1.0 13.805586834533026 -5.967417350739045 2.214239282908079 1.0313069595093667 0.8219086732603121 0.7195903440546053 0.05422615281834458 0.16197319220870213 1.6020220034654031 0.0177612625457895 0.02832866684523678 1.077910368017579e-06 5.967417350739045 -0.20939828624905454 RS(ph)WGQQAQEYQEQK ddPTM_PC-9_Lapatinib_30min_R1 2 RSWGQQAQEYQEQK 14 1 Q5VZK9-2;Q5VZK9 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 RS(1)WGQQAQEYQEQK;RS(1)WGQQAQEYQEQK 163.11 1.6705e-05 26740000.0 95009.0 85955.0 93053.0 84772.0 100133.0 98689.0 91609.0 75755.0 95982.0 68191.0 True False 93654.15423748341 85755.97647855943 85402.54153496744 91006.41567110189 94243.37380905253 94468.30152529535 96352.06577372049 79274.85385722418 85171.49642473216 79977.7234912038 1.1710030012017507 1.0722482803351003 1.0678291129949489 1.1378970505594732 1.1783702973168237 1.181182676894839 1.2047362886531472 0.9912116824123293 1.0649402446932563 1.0 16.287310595997653 -7.771355986803787 24.9999316381079 1.0210569460279857 1.1414356769069363 0.6096107033120233 0.0461545556661052 163.80272728456185 412942.56993220496 0.02752639459513983 0.013472856929304592 1.692949537902192e-08 7.771355986803787 0.12037873087895057 RS(ph)YDVPPPPMEPDHPFYSNISK ddPTM_PC-9_AZD4547_30min_R2 2 RSYDVPPPPMEPDHPFYSNISK 22 1 P18669;Q8N0Y7 P18669 PGAM1;PGAM4 Phosphoglycerate mutase 1;Probable phosphoglycerate mutase 4 1 RS(0.549)Y(0.451)DVPPPPMEPDHPFYSNISK;RS(0.652)Y(0.348)DVPPPPMEPDHPFYSNISK 94.632 6.0665e-05 27745000.0 45302.0 42388.0 72123.0 106135.0 88969.0 84117.0 58150.0 77861.0 57939.0 69569.0 True False 59707.093659863196 56089.09205748174 71166.60189566898 81667.21551940395 76617.1900667267 78857.15069253399 63325.23734852334 65829.37151778593 61001.53725518718 67133.41048515572 0.8893797176156483 0.8354870049374885 1.0600772608060045 1.2164913852762165 1.141267656641219 1.174633466744112 0.9432745467702043 0.9805754100984019 0.9086613776113103 1.0 16.034743315051728 -5.266707062830541 23.894266955831114 1.0618280751257723 0.8624333491533419 0.38401582162197023 0.09609963963212229 230.95218827257654 1047612.3629080437 0.02802647071333487 0.06137532805354622 5.411191916766795e-06 5.266707062830541 -0.19939472597243035 RS(ph)YDVPPPPMEPDHPFYSNISK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSYDVPPPPMEPDHPFYSNISK 22 1 P18669;Q8N0Y7 P18669 PGAM1;PGAM4 Phosphoglycerate mutase 1;Probable phosphoglycerate mutase 4 1 RS(0.546)Y(0.454)DVPPPPMEPDHPFYSNISK;RS(0.545)Y(0.455)DVPPPPMEPDHPFYSNISK 84.946 7.9746e-05 19751100.0 63576.0 64960.0 69219.0 84787.0 87850.0 79470.0 74811.0 74949.0 70103.0 51447.0 True False 74338.16111676274 71408.79949431609 70869.44347451931 80036.65927316286 70636.42313650167 75302.45330106045 67724.36049526358 72981.6681650296 71128.12375315382 60773.933845772066 1.2231915298656335 1.1749905753267915 1.166115783361448 1.3169570276012479 1.1622815682091265 1.2390584011256844 1.1143652584203259 1.2008712213732533 1.1703722180245548 1.0 15.891165058895036 -10.618996321387158 0.34214084682011114 0.8955922680930206 1.2138209014811234 0.596202682918419 0.04994558298727448 10.913618269122702 0.9345693360965212 1.125683467980522 0.04194725354066968 2.4043831658133175e-11 10.618996321387158 0.3182286333881028 RS(ph)YDVPPPPMEPDHPFYSNISK ddPTM_PC-9_Lapatinib_30min_R1 2 RSYDVPPPPMEPDHPFYSNISK 22 1 P18669;Q8N0Y7 P18669 PGAM1;PGAM4 Phosphoglycerate mutase 1;Probable phosphoglycerate mutase 4 1 RS(0.539)Y(0.461)DVPPPPMEPDHPFYSNISK;RS(0.551)Y(0.449)DVPPPPMEPDHPFYSNISK 101.17 2.8968e-05 27251000.0 42412.0 40022.0 47103.0 43680.0 49277.0 58684.0 44496.0 44467.0 56144.0 34262.0 True False 41807.19710259175 39929.331517944345 43230.37316283811 46892.37291220846 46378.62374230951 56174.22211908552 46799.78515939989 46533.09915476451 49820.47149746996 40184.141048754704 1.0403904627914735 0.993658952906292 1.0758068241495435 1.166937296365618 1.1541524226196387 1.3979201907272407 1.164633209469839 1.157996611108515 1.2398043157628695 1.0 15.29433862362718 -5.715472303342464 2.04364775762943 1.201743877936983 1.0157232908116 0.3446261599448841 0.09349927587611329 0.3270083624962303 2.777340504756948 0.02774627539719477 0.05689087384748538 1.9254298333526795e-06 5.715472303342464 -0.18602058712538283 RS(ph)YEAIAK ddPTM_PC-9_Lapatinib_30min_R1 1 RSYEAIAK 8 1 Q9UPQ4 Q9UPQ4 TRIM35 Tripartite motif-containing protein 35 1 RS(0.982)Y(0.018)EAIAK 52.725 0.046415 2511800.0 6207.3 6959.6 6733.9 8668.8 8580.7 8120.8 6873.9 7053.5 9833.5 8147.0 True False 6118.782763720594 6943.485473796553 6180.264735605702 9306.332470269068 8076.000096305274 7773.492314509401 7229.796907748984 7381.231360067722 8725.947678654364 9555.198094804873 0.6403616861744974 0.7266710124588314 0.6467960867253909 0.9739549487026216 0.8451944183863824 0.8135354429476267 0.7566349578539663 0.7724833422428856 0.9132147331826255 1.0 13.222070067590632 -1.7880647708339856 0.0885659847998495 1.0962633850539782 2.828077206562873e-17 0.47992781311097543 0.08578017235311591 159.63025975538127 1.0781625537676802 1.8780191514889526 21.276605919053033 0.016290530569672775 1.7880647708339856 -1.0962633850539782 RS(ph)YSLSELSVLQAK ddPTM_PC-9_AZD4547_30min_R2 1 RSYSLSELSVLQAK 14 1 Q9P0V3;Q9P0V3-2 Q9P0V3 SH3BP4 SH3 domain-binding protein 4 1 RS(0.848)YS(0.118)LS(0.034)ELSVLQAK 122.44 0.0006324 0.0 54487.0 26951.0 59775.0 135560.0 100210.0 60935.0 50408.0 75722.0 58914.0 81565.0 True False 71812.73259999476 35662.38369446994 58982.344443708855 104308.73638112204 86297.57125051085 57124.724817213784 54894.214346764624 64020.904818455914 62028.07376468526 78709.43417645372 0.9123777009881983 0.4530890619099191 0.7493681673721609 1.3252380413163543 1.0964069574816884 0.7257671893454279 0.6974286490702085 0.8133828617663733 0.7880640283301799 1.0 16.264248948241054 -1.522878976298252 0.018290348069882174 1.5282877319492356 2.9358169387381037e-08 0.021540244295648048 0.22646161588037142 25952.971721464277 36.74559073356049 1168.7844650527318 2005.5882945543578 0.029999984041852067 1.522878976298252 -1.5282877025910662 RS(ph)YSLSELSVLQAK ddPTM_PC-9_Lapatinib_30min_R1 1 RSYSLSELSVLQAK 14 1 Q9P0V3;Q9P0V3-2 Q9P0V3 SH3BP4 SH3 domain-binding protein 4 1 RS(0.77)YS(0.191)LS(0.039)ELSVLQAK 117.78 5.7341000000000005e-05 4509000.0 122920.0 39216.0 51418.0 39615.0 34253.0 30089.0 20839.0 18269.0 51539.0 33591.0 True False 121167.13825923295 39125.19776142385 47190.61051921975 42528.419251766005 32238.305883989055 28802.163610884818 21917.941453989893 19117.844434263454 45734.1350902697 39397.159592806 3.075529797365349 0.9930969177932358 1.1978175839822942 1.0794793251930725 0.8182901056114673 0.7310720851090025 0.5563330372170321 0.48525946113522384 1.1608485373808737 1.0 15.265803999355724 -3.0379531987689403 1.3076677956873595 0.817718569344552 199.99999936317644 0.8761210320778272 0.24450336892093205 42.65685772074133 1.0767323493338392 0.07344006259145719 24603.509772180147 0.0009163192308594469 3.0379531987689403 199.1822807938319 up RS(ph)YSSPDITQAIQEEEKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSYSSPDITQAIQEEEKR 18 2 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 RS(0.321)Y(0.27)S(0.321)S(0.088)PDIT(0.001)QAIQEEEKR 40.724000000000004 0.04503 3800200.0 11100.0 10388.0 11910.0 15765.0 18000.0 14349.0 13701.0 15106.0 10899.0 5798.7 True False 12979.01076500673 11419.251988099692 12193.97956892653 14881.738160819608 14473.02921408116 13596.513180029166 12403.142093349981 14709.48350613002 11058.377256117763 6849.95840751606 1.8947576018513657 1.6670542080328563 1.7801538116708544 2.1725297112009825 2.1128638092460164 1.9849044871733095 1.8106886721736495 2.1473828935939467 1.6143714455235305 1.0 12.74187951281518 -8.58197120687187 4.602640633693508 1.0002099744467208 1.9396749638515103 0.7718261546057237 0.157686067209383 0.15169363087792734 9.607052880777818 0.1645669697175462 0.04289843204387179 2.6183565959135183e-09 8.58197120687187 0.9394649894047895 RS(ph)YSSPDITQAIQEEEKR ddPTM_PC-9_Lapatinib_30min_R1 1 RSYSSPDITQAIQEEEKR 18 2 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 RS(0.428)Y(0.044)S(0.428)S(0.1)PDITQAIQEEEKR 57.806000000000004 0.010643999999999999 6720100.0 18812.0 16446.0 25171.0 18403.0 15511.0 13429.0 15248.0 13632.0 19701.0 12956.0 True False 18543.737430301713 16407.92029743922 23101.53754286984 19756.418010608344 14598.673475799309 12854.672974527977 16037.466830962992 14265.392486062683 17482.065919272853 15195.427337215151 1.2203498472784775 1.0797932781564195 1.5202953513713837 1.3001554725758098 0.960728063240819 0.845956661123019 1.0554140054808199 0.9387950841714916 1.150482018788474 1.0 13.89134962753318 -6.260639046964513 24.824335878180317 0.9847146553032997 1.2829907609618831 0.5599129856593662 0.12508789236617843 50.31724429104374 1560713.740879552 0.038967918525455295 0.047397260983686615 5.487328410753296e-07 6.260639046964513 0.2982761056585834 RSAPT(ph)S(ph)RKLLS(ph)DK ddPTM_PC-9_Lapatinib_30min_R1 1 RSAPTSRKLLSDK 13 3 O75923-15;O75923-3;O75923-9;O75923;O75923-14;O75923-6;O75923-12;O75923-5;O75923-11;O75923-4;O75923-10;O75923-2;O75923-8;O75923-7;O75923-13 O75923-15 DYSF Dysferlin 3 RS(0.074)APT(0.963)S(0.963)RKLLS(1)DK 67.08 0.032367 2499400.0 11097.0 20194.0 14856.0 14452.0 17341.0 13258.0 14402.0 12306.0 15425.0 12705.0 True False 10938.754745059436 20147.24203371565 13634.597025818379 15514.848290458713 16321.036473717752 12690.986245907496 15147.665090472796 12877.7816852617 13687.674067549051 14901.042321651643 0.734093260655002 1.3520693115837359 0.9150096168780701 1.0411921498884136 1.0952949546356778 0.8516844642114147 1.0165507058833598 0.8642201939491114 0.9185715852682645 1.0 13.863125629678711 -6.755155978273903 24.996787510295697 0.9271157328927643 1.0400693841816862 0.08941063286875528 0.15254045472226146 328.4308249597096 1306570.082917011 0.04763882974168074 0.04652413429387242 1.7572923633470801e-07 6.755155978273903 0.11295365128892187 RSAS(ph)ASHQADIK ddPTM_PC-9_AZD4547_30min_R2 1 RSASASHQADIK 12 1 C9JXK0;A0A494C1L1;Q14739 C9JXK0 LBR Lamin-B receptor 1 RS(0.041)AS(0.922)AS(0.037)HQADIK 58.658 0.030876 9177700.0 21215.0 22108.0 53930.0 56247.0 47660.0 26819.0 31129.0 47417.0 31884.0 34879.0 True False 27960.92870058713 29253.978654496725 53214.852962763965 43280.12315748729 41043.23167148335 25142.00369037263 33899.42069513642 40089.79218426247 33569.32314752391 33657.89682634137 0.8307390341366881 0.8691564658788172 1.5810510453854894 1.2858831727006592 1.219423539243904 0.7469867716361878 1.0071758455390483 1.1910961754712899 0.9973684131461197 1.0 15.03865740966338 RSAS(ph)ASHQADIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSASASHQADIK 12 1 C9JXK0;A0A494C1L1;Q14739 C9JXK0 LBR Lamin-B receptor 1 RS(0.159)AS(0.716)AS(0.125)HQADIK;RS(0.378)AS(0.616)AS(0.006)HQADIK 70.45100000000001 0.013634 58004000.0 142351.0 127405.0 146234.0 169348.0 301275.0 168122.0 169327.0 132487.0 151168.0 121473.0 True False 166448.21273959213 140052.92640968808 149720.77315553327 159859.98059362342 242242.3264706836 159305.3863581337 153287.12073868111 129009.3566315798 153378.5460182409 143495.09332026137 1.1599575211126039 0.9760119539217216 1.0433860119619354 1.1140449258208283 1.6881575590186344 1.1101800254771494 1.0682394581713348 0.8990506479803362 1.0688765899187995 1.0 17.130641880581315 -7.311793219958284 3.3841865028516227 0.9916867775536042 1.1875635659797312 0.18092528717090095 0.18528221510044618 0.4772062345155487 11.092677194456634 0.09013787031536005 0.05983821900576414 4.877606716508686e-08 7.311793219958284 0.195876788426127 RSAS(ph)PDDDLGSSNWEAADLGNEER ddPTM_PC-9_AZD4547_30min_R2 1 RSASPDDDLGSSNWEAADLGNEER 24 1 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 RS(0.268)AS(0.732)PDDDLGSSNWEAADLGNEER 98.06700000000001 2.1567e-06 30286000.0 13593.0 16501.0 16749.0 22733.0 20981.0 22426.0 16467.0 22316.0 15702.0 15780.0 True False 17915.29124803586 21834.625555357812 16526.8973163978 17492.258071348835 18068.150308421977 21023.69867483116 17932.53109919405 18867.57497066455 16531.97566373167 15227.547003058195 1.1765053980419748 1.433889880686147 1.0853289313819654 1.1487246151882382 1.1865437226884472 1.3806359402869621 1.1776375469793399 1.239042307134256 1.0856624287819636 1.0 13.894395937162587 -8.428959913893 2.687979035405855 1.0005682466580912 1.230826902649036 0.36915773087970416 0.09990047744347906 0.27532095831750825 4.047353551664609 0.09567437146369592 0.02599281450517956 3.7242608021821235e-09 8.428959913893 0.23025865599094475 RSAS(ph)PDYNR ddPTM_PC-9_Lapatinib_30min_R1 1 RSASPDYNR 9 1 Q14669;Q14669-2;Q14669-3;G5E9G6;F8W9P3;C9JLJ5;C9JSX9;C9JLD7 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 RS(0.079)AS(0.905)PDY(0.015)NR 80.245 0.027867000000000003 10343000.0 52947.0 49930.0 55961.0 42355.0 46939.0 49859.0 48712.0 51616.0 52052.0 39618.0 True False 52191.966070709386 49814.39015269005 51360.102595706914 45469.927992138066 44178.14030562466 47726.64679700573 51234.06901035348 54014.267793472114 46189.35562814022 46465.91851233331 1.1232311281408593 1.072062960284923 1.1053284695550472 0.978565138663279 0.950764382154602 1.027132322464212 1.102616081865563 1.1624491567757402 0.9940480486978929 1.0 15.503885306071863 -5.719212925289159 24.99936712331813 1.037070217517949 1.0973931711297313 0.21625213757996287 0.05965211737521913 288.70943585960424 170922.864448812 0.018060719017710444 0.03128179347808184 1.9089171278918203e-06 5.719212925289159 0.060322953611782415 RSAT(ph)S(ph)T(ph)SASPTLR ddPTM_PC-9_AZD4547_30min_R2 1 RSATSTSASPTLR 13 1 O75061-4;O75061;O75061-2 O75061-4 DNAJC6 Putative tyrosine-protein phosphatase auxilin 3 RS(0.117)AT(0.942)S(0.942)T(0.96)S(0.017)AS(0.015)PT(0.008)LR 99.973 0.0087276 1935900.0 7326.3 7799.8 14240.0 17317.0 12783.0 12423.0 9623.9 15428.0 11456.0 14843.0 True False 9655.91100349335 10320.932816597779 14051.16829574929 13324.83319498297 11008.301100641453 11646.187846135177 10480.408456035315 13043.95710017085 12061.540772112468 14323.351087857585 0.6741377031300314 0.7205669087694988 0.9809972686951007 0.9302874106241036 0.7685562570600941 0.8130909990754932 0.7317008702607263 0.9106777471389832 0.842089305647019 1.0 13.806081444235343 -14.52287874527968 0.15590786902458942 1.6405390436431058 0.7729764290450492 0.2844396807485774 0.09184453822192175 206.63200566043105 1.8700790367616786 41.01553978214823 0.45556426991249377 3.0000000000045413e-15 14.52287874527968 -0.8675626145980566 RSDLDLGYEPEGSASPT(ph)PPYLK ddPTM_PC-9_AZD4547_30min_R2 2 RSDLDLGYEPEGSASPTPPYLK 22 1 O15169-2;O15169 O15169-2 AXIN1 Axin-1 1 RSDLDLGYEPEGSAS(0.006)PT(0.983)PPY(0.011)LK;RSDLDLGYEPEGS(0.006)AS(0.199)PT(0.788)PPY(0.008)LK 124.82 2.1163e-06 18877200.0 63471.0 56986.0 82880.0 129322.0 102830.0 85117.0 74952.0 90065.0 82191.0 94005.0 True False 83653.45772118607 75405.61007803287 81780.95704717003 99508.81090498292 88553.82947500261 79794.62053445133 81622.58279873624 76147.52373780707 86535.44846374795 90713.91356289515 0.92216788401689 0.8312463558939226 0.9015260596211453 1.096952021984918 0.9761879517369199 0.8796293468159866 0.8997801946020599 0.8394249652233482 0.9539379910420233 1.0 16.46903622565855 -5.747270077852253 0.005137765412619334 1.840163372916547 2.925440143746621e-07 0.03870088974213304 0.07451351685593476 108846.02000829336 124.40850953913909 21703.804762086886 22860.34860306794 1.789492663184945e-06 5.747270077852253 -1.8401630803725326 RSDLDLGYEPEGSASPT(ph)PPYLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSDLDLGYEPEGSASPTPPYLK 22 1 O15169-2;O15169 O15169-2 AXIN1 Axin-1 1 RSDLDLGYEPEGS(0.135)AS(0.135)PT(0.698)PPY(0.031)LK;RSDLDLGYEPEGS(0.022)AS(0.281)PT(0.673)PPY(0.023)LK 65.598 0.0024850000000000002 15180900.0 60469.0 50380.0 59678.0 85152.0 85766.0 83588.0 84537.0 84149.0 76057.0 64713.0 True False 70705.2073828102 55381.39345017927 61100.94985007532 80381.20950650897 68960.76797638265 79204.4981317359 76529.04336512125 81940.17791323553 77169.18973929257 76444.95463217386 0.9249165981328487 0.7244610676617572 0.7992803468073403 1.0514913625532905 0.9020970488922064 1.036098438580283 1.001099990618766 1.0718847085135015 1.0094739425329438 1.0 16.2221336663894 -5.755504981949724 24.99911102548939 1.0094840327494652 0.8070434505496569 0.670017166344326 0.06231629220598429 78.43314413393485 330401.391518313 0.016654975937775946 0.02791024265248657 1.7558807517378283e-06 5.755504981949724 -0.20244058219980832 RSDLDLGYEPEGSASPT(ph)PPYLK ddPTM_PC-9_Lapatinib_30min_R1 2 RSDLDLGYEPEGSASPTPPYLK 22 1 O15169-2;O15169 O15169-2 AXIN1 Axin-1 1 RSDLDLGYEPEGSASPT(0.99)PPY(0.01)LK;RSDLDLGYEPEGS(0.003)AS(0.247)PT(0.742)PPY(0.009)LK 122.16 5.78e-07 15480100.0 69453.0 48983.0 62558.0 61299.0 58391.0 58280.0 47870.0 47907.0 68542.0 44787.0 True False 68462.58748387962 48869.58287300655 57414.72272086334 65807.13294746958 54956.55618112291 55787.50025731549 50348.4743702911 50132.934113101895 60822.07818074211 52528.37327507373 1.3033449013424359 0.9303463980712422 1.0930230490900872 1.252792135839794 1.0462261203737186 1.0620450773370573 0.9585005442036588 0.954397233102428 1.1578900009379118 1.0 15.680809286632536 -6.499572369175131 23.891158116529397 1.0233148282152764 1.1288067109874462 0.21142044528560522 0.10752095078784023 774.2806443080337 793708.4235775083 0.03327386897232705 0.03746019912811908 3.1653929504804353e-07 6.499572369175131 0.10549188277216981 RSDS(ph)ASSEPVGIYQGFEK ddPTM_PC-9_AZD4547_30min_R2 1 RSDSASSEPVGIYQGFEK 18 1 Q05655;Q05655-2 Q05655 PRKCD Protein kinase C delta type;Protein kinase C delta type regulatory subunit;Protein kinase C delta type catalytic subunit 1 RSDS(0.997)AS(0.002)S(0.001)EPVGIYQGFEK 118.66 0.00014273 12024000.0 19060.0 22875.0 30656.0 43466.0 44271.0 27272.0 29089.0 36179.0 25907.0 26327.0 True False 25120.6835273717 30268.89640499424 30249.481409725428 33445.58524300572 38124.73582308515 25566.677528761054 31677.86464714007 30588.366860713064 27276.39112981124 25405.29974331515 0.988796974693505 1.1914402392736516 1.190676028834689 1.3164806391157102 1.5006607364716036 1.0063521307395071 1.2468998581870858 1.2040151924899734 1.0736496481207007 1.0 14.632841865359676 -8.394299890381372 2.6447759507551396 1.001651780141823 1.2141004907331348 0.20173966650540354 0.1374042636369937 0.4236245608706306 5.778556708031503 0.13403663494071694 0.03667990558705377 4.033667627021928e-09 8.394299890381372 0.21244871059131176 RSDS(ph)ASSEPVGIYQGFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSDSASSEPVGIYQGFEK 18 1 Q05655;Q05655-2 Q05655 PRKCD Protein kinase C delta type;Protein kinase C delta type regulatory subunit;Protein kinase C delta type catalytic subunit 1 RS(0.043)DS(0.955)AS(0.002)S(0.001)EPVGIYQGFEK 120.9 0.00010843 5758300.0 25492.0 21709.0 25294.0 28591.0 30869.0 24437.0 22756.0 23954.0 18732.0 19699.0 True False 29807.292110049704 23864.12605021717 25897.104888029182 26989.138963272664 24820.44104497062 23155.480701120105 20600.3869408271 23325.23288136093 19005.92006253765 23270.27276280179 1.280917177631778 1.0255198249487076 1.1128835984005507 1.1598118869674614 1.0666158191599207 0.9950670083306808 0.8852662429362418 1.0023618166885864 0.8167467677009429 1.0 14.506200500960317 -6.760378015322745 1.953757026947399 0.9256864895683764 1.1341199357212959 0.6141553850608109 0.07786774894106499 0.22363474519189377 1.7596844375268923 0.030008274694474493 0.02754938996857325 1.7362888833809833e-07 6.760378015322745 0.20843344615291948 RSDS(ph)ASSEPVGIYQGFEK ddPTM_PC-9_Lapatinib_30min_R1 3 RSDSASSEPVGIYQGFEK 18 1 Q05655;Q05655-2 Q05655 PRKCD Protein kinase C delta type;Protein kinase C delta type regulatory subunit;Protein kinase C delta type catalytic subunit 1 RS(0.005)DS(0.964)AS(0.03)S(0.001)EPVGIYQGFEK;RS(0.251)DS(0.735)AS(0.01)S(0.004)EPVGIYQGFEK;RS(0.18)DS(0.585)AS(0.18)S(0.056)EPVGIYQGFEK 164.56 2.2813000000000002e-07 39055000.0 201866.0 213114.0 234556.0 181679.0 170293.0 192386.0 185040.0 169044.0 230515.0 170919.0 True False 198987.3538223097 212620.54762668465 215271.71109234373 195040.27972337772 160276.70054891967 184158.09925367046 194620.46579232643 176898.4013654621 204551.97326943697 200462.12141474837 0.9926431608024968 1.0606519881468328 1.073877247098243 0.9729532858721321 0.7995360890016393 0.9186678159144813 0.9708590551611704 0.8824530046724696 1.0204021179952838 1.0 17.612970130519777 -5.974176277025956 7.288318809089122 0.9237139915814425 1.041500284805526 0.3845454734591207 0.061932457441347434 0.1724500993563947 34.641875432223614 0.017500549449316543 0.025716752398011106 1.0612647100056548e-06 5.974176277025956 0.1177862932240834 RSDS(ph)LLSFR ddPTM_PC-9_AZD4547_30min_R2 3 RSDSLLSFR 9 1 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 RS(0.067)DS(0.933)LLSFR;RSDS(0.983)LLS(0.017)FR;RS(0.349)DS(0.65)LLS(0.001)FR 105.25 0.0012142000000000001 161431900.0 58728.2 51818.0 67280.9 99961.5 93339.3 69178.8 61777.7 96971.5 75314.9 68424.0 True False 77402.54597755468 68567.15514378103 66388.71130544096 76916.92056477962 80380.74934859588 64853.03870000934 67275.79562073722 81986.78285838848 79295.8918555842 66028.49658664459 1.1722597057163753 1.0384479230691728 1.0054554432921805 1.1649049204663764 1.2173645244688835 0.9821977184488401 1.0188903140094352 1.241687863524243 1.2009343837100657 1.0 16.01080117692087 -7.757258177474646 24.998234628543162 1.165983335703515 1.0848820143517985 0.07276892739321905 0.09458174264921901 224.28701612923626 1340978.061774496 0.047233472894800135 0.025975007979539482 1.7488067565944507e-08 7.757258177474646 -0.08110132135171644 RSDS(ph)LLSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RSDSLLSFR 9 1 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 RS(0.055)DS(0.945)LLSFR;RS(0.186)DS(0.814)LLSFR;RS(0.089)DS(0.911)LLSFR 93.839 0.0027259 60881500.0 21799.9 23947.0 29466.3 25967.199999999997 33687.4 25472.0 29252.9 30330.1 29321.6 23467.2 True False 25490.192502348666 26324.299899790443 30168.888343565046 24512.341970798272 27086.595797024303 24136.203479106764 26481.853539344407 29533.967012397312 29750.37292898272 27721.61759374701 0.9195059565390703 0.9495946551736667 1.088280229014127 0.8842320217391414 0.9770929025128049 0.8706636038638313 0.9552780767496681 1.065376755613969 1.0731831513213472 1.0 14.758723822680729 -7.7543359827374685 22.523653739925248 1.05195998294601 0.9501463176129451 0.3609167376922364 0.05896188363073136 49.24629328248231 156156.85242763808 0.02868764090385125 0.01604818918112273 1.76061345805859e-08 7.7543359827374685 -0.1018136653330649 RSDS(ph)LLSFR ddPTM_PC-9_Lapatinib_30min_R1 2 RSDSLLSFR 9 1 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 RS(0.07)DS(0.93)LLSFR;RS(0.095)DS(0.905)LLSFR 105.25 0.0012142000000000001 61221400.0 32803.4 24766.4 31150.9 30859.0 36279.9 29778.3 25651.7 22011.5 29025.5 25336.0 True False 32335.61750059321 24709.054922443072 28589.793247951366 33128.47380260628 34145.98761102776 28504.751525607724 26979.819511267953 23034.23464693142 25756.342537934834 29715.293841902072 1.0881809775340727 0.8315265214574586 0.9621238612029601 1.1148627363021806 1.1491048277260476 0.9592619772587495 0.9079438909408738 0.7751642897924311 0.866770582009704 1.0 14.858918026766183 -7.2135835996422735 3.1511480813615624 0.8651567914553326 1.020692166753887 0.29974282336600133 0.09885314051390381 0.3241760834176307 6.4690379730534655 0.0451390581180018 0.03221765728709381 6.115280753497653e-08 7.2135835996422735 0.15553537529855443 RSDS(ph)PEIPFQAAAGPSDGLDASSPGNSFVGLR ddPTM_PC-9_AZD4547_30min_R2 2 RSDSPEIPFQAAAGPSDGLDASSPGNSFVGLR 32 1 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 RS(0.161)DS(0.839)PEIPFQAAAGPSDGLDASSPGNSFVGLR;RS(0.281)DS(0.719)PEIPFQAAAGPSDGLDASSPGNSFVGLR 137.42 2.0207000000000002e-16 48476000.0 58802.0 41347.0 84990.0 120115.0 89659.0 71721.0 84256.0 110249.0 77073.0 83754.0 True False 77499.81284241918 54711.6091653463 83862.97706852043 92424.3425082509 77211.39547699392 67236.27453213086 91754.62077449997 93212.5503199857 81146.92143235191 80821.79795273369 0.958897411410505 0.6769412528702073 1.0376282041828033 1.1435571201014687 0.9553288522750853 0.8319076812848444 1.1352707202598986 1.153309536302303 1.0040227202048682 1.0 16.302456825461327 -5.288868580209988 23.935963425611035 1.0358017674497848 0.8179193566485764 0.37008741630374775 0.11198513749686227 392.32842928244986 342362.9834673051 0.030121005562434414 0.06273252654942846 5.141992274276648e-06 5.288868580209988 -0.2178824108012084 RSDS(ph)PEIPFQAAAGPSDGLDASSPGNSFVGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RSDSPEIPFQAAAGPSDGLDASSPGNSFVGLR 32 1 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 RS(0.056)DS(0.943)PEIPFQAAAGPS(0.001)DGLDASSPGNSFVGLR;RS(0.093)DS(0.907)PEIPFQAAAGPSDGLDASSPGNSFVGLR;RS(0.37)DS(0.63)PEIPFQAAAGPSDGLDASSPGNSFVGLR;RS(0.074)DS(0.926)PEIPFQAAAGPSDGLDASSPGNSFVGLR 115.93 8.690299999999999e-18 33267000.0 38658.03 34473.31999999999 48184.200000000004 59714.119999999995 72821.8 60756.909999999996 65543.3 57209.9 52944.399999999994 44591.0 True False 45202.07094810388 37895.603383365116 49333.09406759611 56368.53145218912 58552.891045665274 57570.71068317274 59334.56413160105 55708.20074389959 53718.611689035795 52674.99531783822 0.8581314658949071 0.7194230043060277 0.9365562117266979 1.0701193443314858 1.1115879686815373 1.0929419231229927 1.126427516007915 1.0575834019112706 1.0198123676120034 1.0 15.684830660354121 -5.546252000803469 3.1189256797655265 1.0759995770167172 0.7901106281827226 0.8380402687837508 0.0490532047792483 0.08358799874473412 1.6631372138086353 0.013432255007914787 0.027816885223271984 2.8428110782858366e-06 5.546252000803469 -0.2858889488339946 RSDS(ph)PEIPFQAAAGPSDGLDASSPGNSFVGLR ddPTM_PC-9_Lapatinib_30min_R1 5 RSDSPEIPFQAAAGPSDGLDASSPGNSFVGLR 32 1 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 RS(0.238)DS(0.762)PEIPFQAAAGPSDGLDASSPGNSFVGLR;RS(0.274)DS(0.726)PEIPFQAAAGPSDGLDASSPGNSFVGLR;RS(0.217)DS(0.783)PEIPFQAAAGPSDGLDASSPGNSFVGLR;RS(0.369)DS(0.631)PEIPFQAAAGPSDGLDASSPGNSFVGLR;RS(0.323)DS(0.677)PEIPFQAAAGPSDGLDASSPGNSFVGLR 119.89 4.97e-18 39928300.0 62200.5 50319.2 72808.7 62582.9 49118.7 59237.9 46077.5 48498.7 71834.8 48480.0 True False 61313.509463825314 50202.68898400246 66822.64973570954 67185.45523643437 46229.63463707973 56704.4331072895 48463.16749106097 50752.126655208995 63744.00837002083 56859.70340446055 1.0783297448402689 0.8829221043749612 1.1752198083127428 1.181600522227905 0.8130474108919304 0.9972692383555615 0.8523288830110063 0.8925851458315481 1.1210752880047596 1.0 15.795118953098306 -6.257203782035816 24.987968786902595 0.9385550596551987 1.072311311400586 0.2535236854670474 0.1114789791469022 541.0471250292198 3191912.5825675307 0.033913468965699266 0.042240437371064844 5.530905241530246e-07 6.257203782035816 0.1337562517453873 RSDSAS(ph)SEPVGIYQGFEK ddPTM_PC-9_AZD4547_30min_R2 1 RSDSASSEPVGIYQGFEK 18 1 Q05655;Q05655-2 Q05655 PRKCD Protein kinase C delta type;Protein kinase C delta type regulatory subunit;Protein kinase C delta type catalytic subunit 1 RS(0.233)DS(0.187)AS(0.29)S(0.29)EPVGIYQGFEK 71.05199999999999 0.0043113 7213800.0 11988.0 10657.0 10752.0 18693.0 14755.0 13249.0 9493.6 14330.0 11245.0 11103.0 True False 15799.93463410976 14101.6668410065 10609.421454767999 14383.61765397104 12706.522939839213 12420.537935558637 10338.512008459868 12115.627770640933 11839.38774287751 10714.287349490178 1.474660340788935 1.3161553709568472 0.9902125179863531 1.3424707761506378 1.185941960054285 1.1592500303951292 0.9649276401898824 1.1307917526794198 1.105009354023053 1.0 13.387248273283141 -1.5228787452803376 0.47928185490194425 1.0838188456530227 11.458289185408155 0.5452696924809133 0.10731092172420825 81.77157235829051 0.9181132586498431 0.0637953989806771 844.8180973568318 0.029999999999999995 1.5228787452803376 10.374470339755133 RSDSAS(ph)SEPVGIYQGFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSDSASSEPVGIYQGFEK 18 1 Q05655;Q05655-2 Q05655 PRKCD Protein kinase C delta type;Protein kinase C delta type regulatory subunit;Protein kinase C delta type catalytic subunit 1 RS(0.056)DS(0.392)AS(0.395)S(0.156)EPVGIYQGFEK;RS(0.06)DS(0.052)AS(0.444)S(0.444)EPVGIYQGFEK 69.913 0.0048271 7795000.0 52906.0 45243.0 54846.0 56553.0 63871.0 55044.0 56078.0 56830.0 46323.0 41248.0 True False 61861.940858869035 49734.42603942953 56153.736644613266 53384.5187572998 51355.93605180987 52157.39574057601 50765.88587043869 55338.2727163623 47000.38624049393 48725.93588101168 1.2695895879749823 1.0206971942187129 1.1524403919452715 1.0956078686238953 1.05397536493133 1.0704236829425693 1.0418657939050888 1.1357046656117162 0.9645866290853493 1.0 15.57240227520045 -4.753272670654042 24.99999388490652 1.0673725779539138 1.269589959231443 0.5596189975853045 0.05552031089517373 224.6136622774788 687535.2411874514 0.012977283809317145 0.14200597918841903 1.7649293664681023e-05 4.753272670654042 0.2022173812775292 RSDSAS(ph)SEPVGIYQGFEK ddPTM_PC-9_Lapatinib_30min_R1 1 RSDSASSEPVGIYQGFEK 18 1 Q05655;Q05655-2 Q05655 PRKCD Protein kinase C delta type;Protein kinase C delta type regulatory subunit;Protein kinase C delta type catalytic subunit 1 RS(0.035)DS(0.1)AS(0.432)S(0.432)EPVGIYQGFEK 86.825 0.00078131 6060400.0 32151.0 24927.0 21716.0 25587.0 22620.0 21609.0 24544.0 24705.0 24581.0 21621.0 True False 31692.520844228697 24869.283063010324 19930.594306184143 27468.753335729805 21289.536072631072 20684.83344303931 25814.768225285665 25852.88449003658 21812.428930594706 25358.161041828418 1.2497957084487208 0.9807210791818978 0.785963709012989 1.08323128362581 0.8395536268388655 0.8157071567184849 1.0180063208331263 1.0195094371154168 0.8601739256492216 1.0 14.63016250546718 -4.782652040969297 4.160706173475266 0.927517187217481 1.2753202373670522 0.5024178773718633 0.09553019329290867 0.17212668441172657 5.856551288178763 0.023574189444231602 0.17693705356660303 1.6494834370747303e-05 4.782652040969297 0.34780305014957125 RSDSVSASER ddPTM_PC-9_AZD4547_30min_R2 2 RSDSVSASER 10 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 0 ; 113.67 0.00080585 724100.0 3534.6 3227.18 4027.1 6448.6 5368.3 4663.9 3447.5 5407.3 2188.5 4158.93 False True 4658.529275752778 4270.302824055489 3973.698022739604 4961.9748998768355 4623.004208603103 4372.2655957168 3754.3208213075527 4571.726032392655 2304.1796420886994 4013.3271265797703 1.1607649037378271 1.0640305884296848 0.9901256233069795 1.2363743954521644 1.15191312913057 1.089436633948881 0.935463445390023 1.1391361551652934 0.574132027969612 1.0 11.97058303974829 -8.24024313959187 24.999255894216667 0.7870659714039318 1.0923026279415564 0.4916006269335278 0.12558604393182451 553.8069240682419 653172.9734012306 0.08109935316727523 0.030584671162104442 5.751178676822506e-09 8.24024313959187 0.30523665653762466 RSDSVSASER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSDSVSASER 10 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 0 93.561 0.0042491000000000004 712210.0 2647.4 3257.6 3571.1 3949.7 5189.6 2454.0 2480.0 3539.2 2838.0 3711.9 False True 3095.5525314665606 3580.992999271617 3656.2485674721697 3728.411114100169 4172.735133855313 2325.3079199798985 2245.0764463548626 3446.2997500923684 2879.5003810314915 4384.838086615766 0.7059673516601201 0.8166762212274616 0.8338389001483235 0.8502961889244514 0.9516280992431911 0.5303064501007789 0.5120089731950903 0.7859582684733144 0.6566948024422723 1.0 12.098307855735925 -6.756603216910238 24.999978898209147 0.6720545491560711 0.8320017373780699 0.1763921274698823 0.140439832814675 182.34739239109078 942623.4784994647 0.04638303778594129 0.044976801411813865 1.751446126036845e-07 6.756603216910238 0.15994718822199883 RSDSVSASER ddPTM_PC-9_Lapatinib_30min_R1 1 RSDSVSASER 10 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 0 144.55 8.468200000000001e-05 543920.0 1139.6 2585.3 3393.9 1972.4 1826.9 1460.0 2174.2 2702.8 2314.4 1654.5 False True 1123.3490950229555 2579.31389669036 3114.8666428328606 2117.4568757335173 1719.4453338235933 1397.5592034262293 2286.769437557697 2828.381955056504 2053.727900287553 1940.4781205173258 0.5789032523198323 1.3292156553678236 1.6052057531070982 1.0912036849810034 0.8860936465313992 0.72021384248004 1.1784566975421764 1.4575696191320444 1.0583617916495935 1.0 10.922196451050532 -10.604242304128164 14.982408029566729 1.0000016123832323 1.1171656096638898 0.007251079269289806 0.30126452232368345 0.0 0.0 0.3063108673597993 0.07429129767053022 2.487469107684435e-11 10.604242304128164 0.11716399728065752 RSEACPCQPDS(ph)GSPLPAEEEK ddPTM_PC-9_AZD4547_30min_R2 1 RSEACPCQPDSGSPLPAEEEK 21 1 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3 A0A0G2JMS7 SCRIB Protein scribble homolog 1 RSEACPCQPDS(0.654)GS(0.346)PLPAEEEK 78.921 0.00047925 27783000.0 14877.0 33915.0 21777.0 21101.0 28724.0 27132.0 26667.0 34243.0 27761.0 24885.0 True False 19607.57653917674 44877.36050602752 21488.222751160967 16236.490457200185 24736.168412330822 25435.43175089267 29040.31133917577 28951.531175858858 29228.389784795236 24013.783724404497 0.8165134143042249 1.8688167188088727 0.8948286949600168 0.6761321182675398 1.0300820851981018 1.0592013338174355 1.2093184344649095 1.205621384290068 1.2171505382174026 1.0 14.551575118826147 RSEACPCQPDS(ph)GSPLPAEEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSEACPCQPDSGSPLPAEEEK 21 1 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3 A0A0G2JMS7 SCRIB Protein scribble homolog 1 RSEACPCQPDS(0.5)GS(0.5)PLPAEEEK 81.15100000000001 0.00036195 15303000.0 8056.7 12830.0 9705.4 8595.4 18951.0 10413.0 11598.0 10055.0 11699.0 8960.8 True False 9420.540182921592 14103.677609483926 9936.813543934466 8113.827604662785 15237.687590891786 9866.923948961152 10499.35347775148 9791.066904153131 11870.075742666457 10585.322106346224 0.8899625432535199 1.3323805801836053 0.938735113027599 0.7665168355905105 1.4395109981354584 0.9321326124828672 0.9918785061303705 0.9249663643473908 1.1213712368327444 1.0 13.36977755009079 RSEACPCQPDSGS(ph)PLPAEEEK ddPTM_PC-9_AZD4547_30min_R2 2 RSEACPCQPDSGSPLPAEEEK 21 1 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3 A0A0G2JMS7 SCRIB Protein scribble homolog 1 RSEACPCQPDS(0.013)GS(0.987)PLPAEEEK;RSEACPCQPDS(0.298)GS(0.702)PLPAEEEK 105.37 3.8795e-05 37225500.0 33292.0 64563.0 50824.0 43877.0 50678.0 47145.0 55181.0 58446.0 56051.0 47236.0 True False 43878.16348338188 85431.72715172204 50150.04055218835 33761.83554289239 43642.23446595536 44197.01569717802 60092.00210023845 49414.513655469644 59013.74142961556 45582.282017519436 0.9626144532763283 1.8742310250918672 1.1002090797672945 0.7406789227866238 0.9574385602103372 0.9696095443442478 1.3183192995283177 1.0840728341875754 1.2946640408861887 1.0 15.476185532606936 -5.490218989074706 24.898826550259564 1.0486414116712541 1.4356222045617295 0.2398914621837016 0.2573700819575846 760.5244468287553 579799.9056366051 0.06553037602304704 0.13623017558983608 3.234305288786575e-06 5.490218989074706 0.3869807928904754 RSEACPCQPDSGS(ph)PLPAEEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RSEACPCQPDSGSPLPAEEEK 21 1 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3 A0A0G2JMS7 SCRIB Protein scribble homolog 1 RSEACPCQPDS(0.01)GS(0.99)PLPAEEEK;RSEACPCQPDS(0.371)GS(0.629)PLPAEEEK;RSEACPCQPDS(0.007)GS(0.993)PLPAEEEK 135.13 1.0486e-06 35348900.0 79371.0 94738.0 85629.0 73179.0 133834.0 73481.0 94547.0 79155.0 75371.0 79360.0 True False 92806.94265129285 104142.9625383702 87670.72010979074 69079.01787951893 107610.18843540786 69627.52700409248 85590.82369899741 77077.26512165488 76473.15828707688 93747.3397865856 0.9899688125824845 1.1108897892510878 0.935180884165586 0.7368637663402106 1.147874581618858 0.7427146963593687 0.912994692903752 0.8221808245132087 0.8157368354255904 1.0 16.516490132113034 -5.47304980272998 6.866622400527513 0.8782947865916165 1.0453999519692598 0.23625729250897864 0.11897197140181015 0.31465652726984383 35.425509954042006 0.029775306830005125 0.06151723710669036 3.364729821158565e-06 5.47304980272998 0.1671051653776433 RSEACPCQPDSGS(ph)PLPAEEEK ddPTM_PC-9_Lapatinib_30min_R1 4 RSEACPCQPDSGSPLPAEEEK 21 1 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3 A0A0G2JMS7 SCRIB Protein scribble homolog 1 RSEACPCQPDS(0.002)GS(0.998)PLPAEEEK;RSEACPCQPDS(0.001)GS(0.999)PLPAEEEK;RSEACPCQPDS(0.017)GS(0.983)PLPAEEEK;RSEACPCQPDS(0.012)GS(0.988)PLPAEEEK 142.21 6.1502e-07 84940600.0 203925.0 289648.0 104018.0 83970.8 142102.0 91322.0 107036.0 100612.8 148771.0 75712.5 True False 201016.9921047354 288977.3378519203 95466.04156109126 90146.29275037702 133743.83974328107 87416.37094197958 112577.80034882964 105287.6379930847 132014.8433519183 88799.30474443531 2.263722589757464 3.254274779330739 1.0750764528601078 1.0151689026149286 1.5061361136576044 0.9844262992099339 1.267777947956112 1.1856808822558111 1.4866652811286918 1.0 16.43826076056535 -5.269903888648059 24.99982448858432 1.1972137327881376 2.7589987028311236 0.8298928770702517 0.28410463082426385 186.51335632636867 550865.9066310682 0.06858815616780216 0.1465108477257628 5.371506571107359e-06 5.269903888648059 1.561784970042986 RSECNMCNT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 RSECNMCNTPK 11 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 RSECNMCNT(1)PK 57.53 0.035078 2283300.0 16950.0 20132.0 22911.0 18627.0 17215.0 15494.0 16779.0 13983.0 15276.0 9961.8 True False 16708.289891750697 20085.385590906404 21027.346019017557 19996.891717850434 16202.447545992214 14831.357738278082 17647.73451972246 14632.701227451194 13555.4560165886 11683.683856735877 1.430053234632674 1.7190969763639041 1.7997188452591408 1.7115228350107938 1.3867584697313748 1.2694076560217356 1.5104597775938784 1.2524047558009839 1.1602039376282514 1.0 13.512207606155952 -7.485265633721397 0.48673445126409315 1.0090590809207882 1.6976911168997313 0.7039970886027918 0.13574559929778104 0.5576315794983816 0.2970873975765721 0.14786501928733972 0.12023692164462708 3.271405400439951e-08 7.485265633721397 0.6886320359789431 RSEEHS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 1 RSEEHSPPR 9 1 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 1 RS(0.001)EEHS(0.999)PPR 70.41199999999999 0.017302 9717200.0 2612.6 2682.7 3592.4 2712.3 2086.5 3044.1 1027.9 2080.4 1130.5 2709.2 True False 3443.3524545441396 3549.830311942207 3544.7624287675367 2087.021139617273 1796.8254906116233 2853.7519457796084 1119.3811086938465 1758.921982836105 1190.2559220385085 2614.3517326163023 1.317096093683698 1.3578243002481263 1.3558858146528467 0.7982939378737286 0.6872929408061926 1.0915715395815264 0.4281677536838665 0.6727946973974579 0.455277653419406 1.0 11.352237537794004 -5.798185239279544 4.571194956968035 0.7133859563514975 1.3502890020117455 0.674603644031486 0.19453612520852998 0.11191161450240122 5.252499581424799 0.0552432363412164 0.08778853661583465 1.591529748343091e-06 5.798185239279544 0.636903045660248 RSEEHS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSEEHSPPR 9 1 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 1 RSEEHS(1)PPR 77.062 0.010820999999999999 501780.0 768.74 975.37 926.25 584.07 1044.5 1153.8 584.97 665.68 1154.0 958.35 True False 898.8724986929075 1072.1982876042346 948.3353128226861 551.3464514804891 839.8377230059872 1093.2926968511838 529.557406783953 648.2066053462614 1170.87506684649 1132.0912687055736 0.7939929611158232 0.9470952715942944 0.8376845039243231 0.48701590297652886 0.7418463035813823 0.9657284064219028 0.4677691820637798 0.5725745116711456 1.034258543646628 1.0 10.144774556967104 -8.280502586874286 24.220764671255576 1.0171294416652354 0.7296086908650192 0.33175268138189173 0.16482905747765222 792.4325348583258 1006811.4550515806 0.16693964989224572 0.043425774415511084 5.242004785999725e-09 8.280502586874286 -0.2875207508002162 RSEEHS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 1 RSEEHSPPR 9 1 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 1 RSEEHS(1)PPR 72.152 0.015153 7297800.0 2493.7 2040.8 2665.3 2656.4 3028.0 1074.4 2342.4 905.45 2616.3 2596.2 True False 2458.1393807114277 2036.0746529863775 2446.169322355528 2851.7605174906257 2849.898993277052 1028.4504165487263 2463.6780105487774 947.5205125077364 2321.624743139615 3044.949710780951 0.8072840651548817 0.6686726699549257 0.803352946583853 0.9365542253107434 0.9359428772129462 0.337756125464862 0.8091030212505241 0.3111777213111089 0.7624509314290705 1.0 11.572202685993679 -6.726648700188035 24.99944813223257 0.6113582246308092 0.8257777690400521 0.15962146293802137 0.20685162731876539 284.3575585916588 204329.35675309444 0.0646030572731165 0.06460039698690967 1.8765118004160587e-07 6.726648700188035 0.21441954440924282 RSELSQDAEPAGS(ph)QETK ddPTM_PC-9_Lapatinib_30min_R1 1 RSELSQDAEPAGSQETK 17 1 Q9BVJ6-3;Q9BVJ6;Q9BVJ6-2;X6RJY0 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 1 RS(0.014)ELS(0.014)QDAEPAGS(0.925)QET(0.047)K 74.308 0.0044456 4172400.0 15171.0 19334.0 19563.0 19066.0 22973.0 19328.0 14888.0 18277.0 17682.0 14109.0 True False 14954.658757979329 19289.233310877426 17954.60565536382 20468.1772423115 21621.77330665578 18501.386495768602 15658.827792456523 19126.21614346889 15690.466960285403 16547.72185093923 0.9037291593785473 1.165673044581819 1.0850197880468202 1.2369181345134677 1.3066314204108136 1.1180624536977266 0.9462829949349038 1.1558217086168454 0.9481949903209685 1.0 14.014344992317131 -7.018675230273181 24.26682985559389 1.0265047043184217 1.1503109614145124 0.2186321417065492 0.11279704130067392 857.6966791163642 1114499.6629101925 0.043337565341039296 0.034216774050292685 9.579101382354705e-08 7.018675230273181 0.12380625709609072 RSEPQPEEGS(ph)PAGGQK ddPTM_PC-9_Lapatinib_30min_R1 2 RSEPQPEEGSPAGGQK 16 1 F8WE91;Q9Y6K1-3;Q9Y6K1 F8WE91 DNMT3A DNA (cytosine-5)-methyltransferase 3A 1 RSEPQPEEGS(1)PAGGQK;RSEPQPEEGS(1)PAGGQK 124.2 0.0002316 0.0 26792.0 22157.0 24696.0 22158.0 24146.8 20813.5 20038.7 21033.0 22872.0 21742.6 True False 26409.941166948953 22105.696827822034 22665.590209316815 23787.573236921144 22726.532698435352 19923.35512363825 21076.20583588787 22010.26996474153 20295.91450716253 25500.779439806596 1.0356523113063423 0.8668635748958773 0.8888195069808704 0.9328174965424333 0.8912093354667953 0.7812841631239704 0.8264926131233469 0.8631214593536541 0.7958938884621192 1.0 14.638253723761355 -6.531105891128028 24.33840039078422 0.8423602034223769 0.9220105443278119 0.20444280247651492 0.06971125546180938 202.61245259175797 599382.6184187243 0.021801330111964664 0.021840317407228894 2.9437038026181604e-07 6.531105891128028 0.07965034090543499 RSES(ph)PDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSESPDSR 8 1 Q9Y4X4 Q9Y4X4 KLF12 Krueppel-like factor 12 1 RS(0.002)ES(0.982)PDS(0.016)R 77.744 0.033947000000000005 292190.0 3118.8 4232.7 3397.1 3338.8 7090.5 7326.4 2588.3 2621.4 5397.6 6623.1 True False 3646.7512408921607 4652.8944830602195 3478.099747573493 3151.737860535648 5701.167424580138 6942.190686609912 2343.117486330762 2552.591027602886 5476.5296887440345 7823.815601569245 0.46610904788716156 0.5947091189274675 0.44455287863326953 0.40283897538478475 0.7286939921534754 0.8873152231779973 0.2994852646911561 0.32625909883291543 0.6999819484045089 1.0 12.933656652672505 -8.53380808757901 21.662539070714462 1.0000000109157896 0.5260539454572923 0.4290384753647668 0.17115937704586523 255.6250606078336 506664.7284382908 0.17621319223677 0.04549804686349967 2.9254448307648372e-09 8.53380808757901 -0.47394606545849727 RSES(ph)PPAELPSLR ddPTM_PC-9_AZD4547_30min_R2 1 RSESPPAELPSLR 13 1 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 RS(0.416)ES(0.584)PPAELPSLR 122.46 8.3187e-05 5916300.0 9907.1 11402.0 17204.0 22075.0 16580.0 10070.0 9440.0 16642.0 9958.8 15595.0 True False 13057.351719518572 15087.473521737453 16975.86371910609 16985.94980535018 14278.153191632256 9440.32130810442 10280.141712296827 14070.361295115592 10485.201836706847 15049.023796748577 0.8676544004362385 1.002554964727824 1.128037535748586 1.1287077510648955 0.9487760391951223 0.6273045637780207 0.6831102037673638 0.934968373041949 0.6967363450493201 1.0 13.87738228452328 -6.558075675443276 8.203172317189804 0.7782912162281163 1.0369095480529085 0.4565049746623624 0.12601139703121314 0.20688042615117092 42.20019758634782 0.041858633824798826 0.04204268900430338 2.766459550191919e-07 6.558075675443276 0.2586183318247922 RSES(ph)PPAELPSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RSESPPAELPSLR 13 1 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 RS(0.237)ES(0.763)PPAELPSLR;RS(0.06)ES(0.81)PPAELPS(0.13)LR;RS(0.239)ES(0.761)PPAELPSLR 125.61 6.3935e-05 24268500.0 63094.0 72472.0 70974.0 76011.0 86883.0 70679.0 82539.0 71244.0 63975.0 47266.0 True False 73774.56803669686 79666.54120923771 72666.28933039395 71752.35010098692 69858.89984483406 66972.46881673158 74720.30838938875 69373.92048925755 64910.51334619079 55834.951642549844 1.3212972495972553 1.4268220687152284 1.301448057044927 1.285079470657354 1.251167911670529 1.1994721379089406 1.3382353918337961 1.2424819660162496 1.1625426625555593 1.0 15.768880884680328 -14.522878745280035 0.09072641551344514 0.04436916007520128 1.5203937891360844 0.7862177277078238 0.05079517497190894 98.45473072596467 0.6174304876064515 17.985621732499595 1.2274609640392427 3.000000000002087e-15 14.522878745280035 1.4760246290608832 RSES(ph)PPAELPSLR ddPTM_PC-9_Lapatinib_30min_R1 2 RSESPPAELPSLR 13 1 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 RS(0.015)ES(0.985)PPAELPSLR;RS(0.01)ES(0.99)PPAELPSLR 146.1 3.0735e-05 22018300.0 34687.2 36618.0 40083.0 32058.2 38768.9 38893.6 37582.0 41259.0 38965.0 28661.1 True False 34192.55416714658 36533.2132708032 36787.53046485446 34415.866971020194 36488.589524590054 37230.21139340985 39527.812069861735 43176.04376338471 34576.35138035974 33615.1329464848 1.0171774189196585 1.0868085314124438 1.0943740881055002 1.023820641310869 1.0854810416094378 1.1075431845734551 1.1758933731658863 1.2844228173103123 1.028594812800687 1.0 15.036823234930456 -6.839898315528877 2.7021381090535628 1.1450529250964034 1.0609755545927386 0.09661857544978081 0.07784939324895276 0.45620850583022876 6.77434330618914 0.029092803232707527 0.025762971629270118 1.4457782415133287e-07 6.839898315528877 -0.08407737050366482 RSET(ph)PPHWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSETPPHWR 9 1 Q13427;E9PG73;C9JM79 Q13427 PPIG Peptidyl-prolyl cis-trans isomerase G 1 RS(0.024)ET(0.976)PPHWR 98.04 0.012062999999999999 4473300.0 2077.4 2067.3 3180.6 2205.6 2721.5 2547.7 2677.9 1006.7 3505.5 1289.4 True False 2429.0627894797267 2272.527881690265 3256.43756649267 2082.027382651678 2188.2416114512157 2414.094127030475 2424.2299256829356 980.2751916868189 3556.761305745555 1523.1580131152155 1.594754299005212 1.4919843260663497 2.137951242387841 1.366914899652101 1.436647801875623 1.584926912535546 1.5915813755427888 0.6435807600039645 2.3351229978242007 1.0 10.572849900100374 RSFS(ph)SQRPVDR ddPTM_PC-9_Lapatinib_30min_R1 1 RSFSSQRPVDR 11 2 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3;H7C5N8 E7EPN9 PRRC2C Protein PRRC2C 1 RS(0.001)FS(0.5)S(0.5)QRPVDR 46.955 0.041535 1478100.0 7702.4 6733.1 7047.5 5481.2 6138.1 6505.6 5189.4 5550.7 5967.4 5464.6 True False 7592.562363552834 6717.509920630433 6468.081754136712 5884.305732747183 5777.0690259689145 6227.3706532943 5458.081740070788 5808.6057858266 5295.288572492203 6409.148828878202 1.184644414768843 1.0481126433455288 1.0091951250988231 0.9181103278853204 0.901378510659438 0.9716377040949884 0.8516078945581484 0.9062990953891275 0.8262077717142107 1.0 12.645917056187209 -4.1878829933448305 0.6639225116589107 0.896767651990497 1.653016529820748 0.7572474369058109 0.049289434554644664 2.8922452912418746 0.5469892753320234 0.020255311044988754 1.9770304207911082 6.488092107403242e-05 4.1878829933448305 0.756248877830251 RSFS(ph)TTSASSQK ddPTM_PC-9_AZD4547_30min_R2 2 RSFSTTSASSQK 12 1 B5MCH3;Q8N3C7;Q8N3C7-3;Q8N3C7-2 B5MCH3 CLIP4 CAP-Gly domain-containing linker protein 4 1 RS(0.199)FS(0.765)T(0.028)T(0.006)S(0.001)ASSQK;RS(0.01)FS(0.952)T(0.027)T(0.007)S(0.003)ASSQK 74.296 0.0096224 7603800.0 28381.0 27090.0 47199.0 67910.0 48192.0 49158.0 35383.0 59171.0 54210.0 51047.0 True False 37405.56763852759 35846.312726176795 46573.11042072128 52254.39869904106 41501.37265447177 46084.14248895697 38532.01845404646 50027.48156431226 57075.42992809159 49259.86006749754 0.7593518858411941 0.7276982248235979 0.9454576273035533 1.0607906442982238 0.842498793086403 0.9355313317133038 0.782219405439816 1.0155831034794434 1.1586600093846164 1.0 15.588124909127815 -3.552479954465259 0.47212946161056407 0.9837361509981088 7.997819081567723e-63 0.3717406793648427 0.10660966906732615 17.312249956947326 1.211280353397876 0.07054237353131734 12.173252824596249 0.0002802334964794156 3.552479954465259 -0.9837361509981088 RSFS(ph)TTSASSQK ddPTM_PC-9_Lapatinib_30min_R1 2 RSFSTTSASSQK 12 1 B5MCH3;Q8N3C7;Q8N3C7-3;Q8N3C7-2 B5MCH3 CLIP4 CAP-Gly domain-containing linker protein 4 1 RS(0.01)FS(0.836)T(0.092)T(0.031)S(0.031)ASSQK;RS(0.013)FS(0.697)T(0.14)T(0.047)S(0.047)AS(0.006)S(0.049)QK 81.128 0.019892 4219800.0 23795.0 20383.4 20433.8 17852.0 22145.0 20246.4 26418.0 21065.0 23416.0 25435.0 True False 23455.67893653144 20336.203489652376 18753.811840749022 19164.895632526226 20842.47463874513 19380.508668663562 27785.794775733255 22043.756801563282 20778.643498588568 29831.405859992854 0.7862746746370424 0.6817044957618115 0.6286600078040544 0.6424402430938874 0.6986755748812076 0.649667962670674 0.9314276003665324 0.7389446177971233 0.6965358453473015 1.0 14.864544348487984 -7.23794974445722 24.820189993078884 0.8199724161666103 0.6778976819103615 0.41810723138416406 0.09127133919357514 786.336563931433 830879.0162299006 0.034433040754749275 0.02665565325290487 5.781629472003561e-08 7.23794974445722 -0.14207473425624884 RSGAASSSSSS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 RSGAASSSSSSR 12 1 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 RSGAASSSS(0.001)S(0.018)S(0.981)R 65.956 0.018521 10829000.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RSGS(ph)VYEPLK ddPTM_PC-9_Lapatinib_30min_R1 1 RSGSVYEPLK 10 1 Q93100-3;Q93100 Q93100-3 PHKB Phosphorylase b kinase regulatory subunit beta 1 RS(0.096)GS(0.897)VY(0.007)EPLK 55.98 0.040161 3904200.0 52893.0 57984.0 46385.0 35321.0 46378.0 46742.0 43420.0 46223.0 43854.0 41678.0 True False 52138.73612061177 57849.741610526326 42571.40435127796 37918.62416740191 43650.137222656245 44742.95362092382 45668.07514430832 48370.68932535766 38914.70071690737 48881.98676755582 1.0666247337397001 1.1834572495102147 0.8709016790523263 0.7757177372456849 0.892969785173051 0.9153260041103899 0.9342516162747163 0.9895401665110405 0.796094907147596 1.0 15.577015303033633 -5.266808107725085 24.921928363333734 0.8940075299877509 1.1250409979463698 0.6093327706190392 0.07305764508609215 243.94301927756786 1132401.1572021863 0.019153591579841082 0.041793695328538626 5.4099330711287785e-06 5.266808107725085 0.2310334679586189 RSGTDT(ph)S(ph)FY(ph)RGKK ddPTM_PC-9_Lapatinib_30min_R1 1 RSGTDTSFYRGKK 13 3 A3KMH1-3;A3KMH1 A3KMH1-3 VWA8 von Willebrand factor A domain-containing protein 8 3 RSGT(0.001)DT(0.999)S(1)FY(1)RGKK 63.16 0.045853 0.0 11548.0 12282.0 12211.0 10108.0 12172.0 13360.0 11118.0 9335.4 11941.0 10851.0 True False 11383.323402356167 12253.561783603831 11207.058715823116 10851.376039299532 11456.066891072736 12788.623943681121 11693.635639208202 9769.156764553234 10596.07883569551 12726.58089195135 0.8944526027061442 0.9628321925296787 0.8806024816068845 0.852654466382424 0.9001684732399633 1.0048750762091183 0.9188356038819184 0.7676183295021152 0.8325943099451615 1.0 13.635557258114924 RSHRMRR ddPTM_PC-9_Lapatinib_30min_R1 1 RSHRMRR 7 3 K7EKF8;O14594 K7EKF8 NCAN Neurocan core protein 0 79.116 0.04166 3783600.0 10165.0 9870.2 11029.0 6541.2 8885.5 7475.5 6378.0 9451.3 9543.3 7461.4 False True 10020.045235967305 9847.346158323277 10122.238193171159 7022.261668803531 8362.872359565134 7155.7902912416275 6708.221632206326 9890.441901666984 8468.43305859584 8751.093048309447 1.1450049931651678 1.125270420959083 1.1566827294936137 0.8024439495772594 0.9556374630459094 0.8177024574803254 0.7665581425285191 1.1301950335881343 0.96770003608084 1.0 13.095247511537163 -5.745208761360694 24.99591726743458 0.9162835153894172 1.1406145919227157 0.5026386059033581 0.10127550754770397 208.87223736727373 321670.52597588394 0.02878916379940298 0.049671455758529534 1.798006422228201e-06 5.745208761360694 0.22433107653329853 RSHS(ph)PSIDGTPK ddPTM_PC-9_AZD4547_30min_R2 2 RSHSPSIDGTPK 12 1 A0A0C4DH56;Q9BWT3-2;Q9BWT3 A0A0C4DH56 PAPOLG Poly(A) polymerase gamma 1 RS(0.058)HS(0.938)PS(0.004)IDGTPK;RS(0.312)HS(0.679)PS(0.009)IDGTPK 84.41 0.0046871000000000005 10013400.0 40777.0 41457.0 66447.0 95737.0 88194.0 75285.0 60568.0 79050.0 66591.0 72187.0 True False 53743.23778571017 54857.164514179036 65565.86936430148 73666.31377190529 75949.78543925319 70577.41704872294 65958.43466423664 66834.63888828806 70110.86431177912 69659.75510201266 0.7715105760421684 0.7875015413683828 0.9412302593984732 1.0575161176496424 1.090296475031087 1.013173487982644 0.9468657270994473 0.9594440691100998 1.0064758942822272 1.0 16.08803778049974 -5.349570458489492 3.044940531308729 1.00934212218655 0.7729191258910555 0.839618703845395 0.039809758844590065 0.106903934198447 1.892323809706625 0.012630052857141284 0.03236433112081516 4.471256057358313e-06 5.349570458489492 -0.23642299629549446 RSHS(ph)PSIDGTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSHSPSIDGTPK 12 1 A0A0C4DH56;Q9BWT3-2;Q9BWT3 A0A0C4DH56 PAPOLG Poly(A) polymerase gamma 1 RS(0.374)HS(0.621)PS(0.005)IDGTPK 64.565 0.020031999999999998 4034500.0 24242.0 23590.0 30287.0 38032.0 42184.0 35766.0 31272.0 31676.0 35934.0 25950.0 True False 28345.691798675067 25931.859299121243 31009.156944087146 35901.19034140764 33918.34802037776 33890.367997555426 28309.6897703263 30844.53856349625 36459.46676955093 30654.529579913018 0.9246820025334571 0.8459389086862257 1.0115685143120416 1.1711545025611025 1.1064710007033813 1.1055582474102865 0.9235075585331043 1.0061983982852485 1.1893663764927487 1.0 14.903812644971403 -5.426570135650643 4.734181036947344 1.070221793083046 0.888309315505421 0.4696965050715808 0.07808337260482641 0.19658904035915808 7.180627529550813 0.021714732884183203 0.046583270531472584 3.7448106596808844e-06 5.426570135650643 -0.18191247757762496 RSIS(ph)SPNVNR ddPTM_PC-9_AZD4547_30min_R2 1 RSISSPNVNR 10 1 Q9NQT8 Q9NQT8 KIF13B Kinesin-like protein KIF13B 1 RS(0.012)IS(0.753)S(0.235)PNVNR 75.788 0.035296 11878000.0 24904.0 26901.0 34974.0 44619.0 44950.0 42570.0 32988.0 41646.0 34305.0 35012.0 True False 32822.95396462038 35596.22217227321 34510.22190839436 34332.77890667814 38709.468393478324 39908.09117040765 35923.86809377625 35210.56762987523 36118.292264954456 33786.24053682342 0.9714887907947864 1.0535715606913145 1.0214282903355842 1.0161763594046238 1.1457169480365568 1.1811936023752647 1.0632691747583767 1.0421570163007468 1.0690237117559542 1.0 15.044148207392793 -6.226168420029163 24.37138821161639 1.0895350608330754 1.0187853181213995 0.2905858681851107 0.05137153770429711 604.4353846314449 417649.75893220847 0.015996177081326717 0.02064978242246036 5.94061735937634e-07 6.226168420029163 -0.07074974271167589 RSIS(ph)SPNVNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSISSPNVNR 10 1 Q9NQT8 Q9NQT8 KIF13B Kinesin-like protein KIF13B 1 RS(0.107)IS(0.876)S(0.016)PNVNR 53.946999999999996 0.044325 8775400.0 6561.4 6673.7 7124.4 11392.0 8722.8 9235.8 7784.3 8043.9 7569.6 8289.1 True False 7672.115426442803 7336.220831053219 7294.272715437458 10753.743173362325 7013.629957143729 8751.458389303314 7046.914750548444 7832.756148216546 7680.291079723742 9791.848213520501 0.7835206652661559 0.7492171723948322 0.7449331889525808 1.0982342596481067 0.7162723322711813 0.8937493921953747 0.7196715672959599 0.799926222038567 0.7843556101205552 1.0 13.257365479202202 RSISES(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 1 RSISESSR 8 1 Q9H307 Q9H307 PNN Pinin 1 RS(0.002)IS(0.153)ES(0.745)S(0.1)R 75.652 0.021662999999999998 0.0 14483.0 12755.0 13217.0 10348.0 11367.0 14141.0 12285.0 12050.0 15019.0 13211.0 True False 14276.469764143088 12725.466581164865 12130.349279095408 11109.026439916053 10698.41540838185 13536.222394281027 12921.057189033338 12609.886990687752 13327.402062918585 15494.503747449015 0.9213892872492634 0.8212890705363804 0.7828807864267693 0.7169656170333962 0.6904651857690646 0.8736144516089845 0.8339122955880814 0.8138296776857935 0.860137393242606 1.0 13.919468929080924 -8.960934601711877 0.7491515369770989 1.0019707660474229 0.7954574683868469 0.45889113346931887 0.06364591150598736 1.4363223842306387 1.3968664926265835 0.07308168936647162 0.024711848188064947 1.0941211122302714e-09 8.960934601711877 -0.2065132976605759 RSLEIT(ph)S(ph)PT(ph)S(ph)VEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSLEITSPTSVEQK 14 1 A0A087WU98;Q6P4D5-3 A0A087WU98 FAM122C 4 RS(0.006)LEIT(0.996)S(0.998)PT(1)S(1)VEQK 53.49100000000001 0.029060000000000002 2193100.0 7354.8 6146.2 9312.6 12447.0 12852.0 10400.0 7808.5 7262.4 7798.8 9836.7 True False 8599.82237607851 6756.354117179277 9534.647702232172 11749.63494371847 10333.742858853955 9854.605691846344 7068.822351355619 7071.769695148851 7912.842696119934 11620.015842725641 0.7400869751362833 0.5814410417872956 0.8205365492854341 1.0111548127599133 0.8893054018788694 0.8480716227263598 0.6083315588404159 0.6085852025387657 0.6809666013556711 1.0 13.50432441526316 -10.81122331052341 14.601809076177522 1.0000183227327166 0.7568489849630728 0.23629669264103315 0.1324539372553827 2.0121707771757193e-10 0.0 0.1459888074722494 0.03540748666859089 1.544460087109727e-11 10.81122331052341 -0.24316933776964378 RSLLEMY(ph)ADFFAHPDLFVS(ph)IS(ph)DQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSLLEMYADFFAHPDLFVSISDQK 24 1 Q96SU4-5;Q96SU4-4;Q96SU4-3;Q96SU4-7;Q96SU4-2;Q96SU4;Q96SU4-6 Q96SU4-5 OSBPL9 Oxysterol-binding protein-related protein 9 3 RS(0.02)LLEMY(0.98)ADFFAHPDLFVS(1)IS(1)DQK 43.799 0.041636 0.0 2473.8 3534.0 2869.6 4253.5 3722.0 2875.1 4868.7 2389.4 2928.4 3134.0 True False 2892.56548022285 3884.8321646076506 2938.0221470186043 4015.190185033062 2992.700818600559 2724.3246946757163 4407.501489664479 2326.680781778568 2971.222310011492 3702.16939126965 0.781316351176155 1.0493393883512598 0.7935947377089131 1.0845506406329133 0.8083640974553624 0.7358725133161494 1.1905185916284984 0.6284641613820481 0.8025624967399232 1.0 11.854155191311378 RSLS(ph)GSSPCPK ddPTM_PC-9_Lapatinib_30min_R1 1 RSLSGSSPCPK 11 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 RS(0.151)LS(0.838)GS(0.006)S(0.006)PCPK 69.714 0.038021 0.0 8378.6 5035.6 5715.2 5323.3 8550.5 7396.6 8303.6 6748.0 7613.8 7874.0 True False 8259.119627552946 5023.940377586339 5245.318317309988 5714.793240008226 8047.576400929794 7080.264660316745 8733.51977817316 7061.536714785146 6756.253667131598 9235.010408554499 0.8943270513157653 0.544010256115424 0.5679818522403817 0.618818278181316 0.8714203931459816 0.7666764136787775 0.9456967985746066 0.7646484846669973 0.7315913429694894 1.0 13.172897871897034 -6.259180003475811 24.668871951210388 0.8358561032461331 0.6419574501668496 0.3785869575523636 0.11844509160187401 178.1002073749398 1944575.92240637 0.03503394436306294 0.0430509304060558 5.505794486153202e-07 6.259180003475811 -0.19389865307928356 RSLS(ph)PILPGR ddPTM_PC-9_AZD4547_30min_R2 1 RSLSPILPGR 10 1 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 RS(0.119)LS(0.881)PILPGR 59.898 0.032345 7062300.0 8222.2 4775.9 10236.0 18151.0 13455.0 9079.1 7273.9 11913.0 7665.6 9002.2 True False 10836.68856761572 6319.616277185218 10100.263951916417 13966.567380154529 11587.005500205802 8511.38244174884 7921.263008588548 10072.119583506312 8070.7879663674385 8687.035718056424 1.2474552792606963 0.7274767230494505 1.162682447698762 1.6077483543810396 1.3338273119013024 0.9797798372185255 0.9118487900451265 1.1594426350257687 0.9290612158520213 1.0 13.08464825405822 -6.781322129245661 24.549833769719385 1.0007304678180804 1.20752655722911 0.211419372574572 0.21186033545719032 387.9709150736177 479035.7188954001 0.08282234997629859 0.07314311008431881 1.6545422845754721e-07 6.781322129245661 0.20679608941102967 RSLS(ph)PILPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSLSPILPGR 10 1 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 RS(0.2)LS(0.8)PILPGR 81.494 0.0074302 2296300.0 1749.0 2961.4 3910.9 5166.2 6178.7 3392.8 4261.6 4420.2 5060.0 3274.7 True False 2045.0711556753852 3255.3882207892207 4004.150688170842 4876.754563046387 4968.028089169072 3214.875595316953 3857.9103966878547 4304.174433589027 5133.992927420484 3868.377187489063 0.5286638444382996 0.841538470270597 1.0350983097307294 1.2606719372708985 1.2842667217758525 0.8310657000342064 0.9972942682954858 1.1126563478632334 1.327169683459157 1.0 11.917512756826769 -4.926184662918773 1.886645882256602 1.1114522351965344 0.44387817004051944 0.6190330357941947 0.14353157420847917 0.4173991910224407 1.9897099965784772 0.042224655129334106 0.44872650785511803 1.1852646640007156e-05 4.926184662918773 -0.6675740651560149 RSLS(ph)PILPGR ddPTM_PC-9_Lapatinib_30min_R1 1 RSLSPILPGR 10 1 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 RS(0.373)LS(0.627)PILPGR 61.03 0.030088999999999998 6123800.0 10703.0 7123.2 8758.5 6912.5 9163.0 6131.8 5859.0 5728.4 10391.0 6207.1 True False 10550.373257310184 7106.706668048102 8038.409938787707 7420.868309424015 8624.050355151125 5869.557207923939 6162.3503516928295 5994.562376552339 9220.656157919098 7279.98896455914 1.449229292609112 0.976197450661722 1.1041788631714629 1.0193515876948045 1.1846240972527873 0.8062590804049916 0.8464779798008949 0.8234301460806344 1.2665755680135815 1.0 12.829720548164648 -2.815461895391185 1.5434834892819538 0.9887272781894335 199.99999974713725 0.44093860152283715 0.14734567809773122 585.1865359994368 4.2166501713348925 0.042077703013942085 409773.52018039965 0.0015294599339765096 2.815461895391185 199.01127246894782 RSLS(ph)PQEDALTGSR ddPTM_PC-9_Lapatinib_30min_R1 2 RSLSPQEDALTGSR 14 1 Q96EN8 Q96EN8 MOCOS Molybdenum cofactor sulfurase 1 RS(0.473)LS(0.525)PQEDALTGS(0.002)R;RS(0.002)LS(0.998)PQEDALTGSR 113.52 0.00029547 8236100.0 43802.0 24968.0 44823.0 27532.0 28698.0 32358.0 20114.9 19155.3 35217.0 20559.6 True False 43177.375447696984 24910.18813002936 41137.825961783565 29556.795124059616 27010.040062438842 30974.12377018215 21156.35109903841 20045.325167860665 31250.49060854942 24113.299466055018 1.7906042061344203 1.033047682466522 1.7060222728828323 1.22574661197517 1.1201304118692528 1.2845244929581416 0.8773727182719565 0.8312974836180774 1.2959856718298393 1.0 14.55754145054929 -6.295231035390991 0.9750979178821905 1.0064387200177778 1.4862194075798751 0.3996936839731816 0.23671976346607457 0.5798761021271717 1.1717604133085402 0.10868172072127327 0.16453690185339495 5.067210717703387e-07 6.295231035390991 0.47978068756209735 RSMRLLK ddPTM_PC-9_Lapatinib_30min_R1 1 RSMRLLK 7 2 Q9H967;A0A0C4DFX7;C9JE56 Q9H967 WDR76 WD repeat-containing protein 76 0 83.75299999999999 0.015565 0.0 22959.0 17582.0 14220.0 14225.0 14593.0 14239.0 14312.0 14407.0 14453.0 11620.0 False True 22631.600449835056 17541.28995923486 13050.886490787376 15271.153953208923 13734.668430941865 13630.031162730193 15053.005330846172 15076.401815339294 12825.150943162811 13628.501517323255 1.6606081322343411 1.2871033500592886 0.9576171286475135 1.1205306712405383 1.007790065069418 1.0001122387083416 1.1045238767968895 1.106240608784143 0.9410536387188789 1.0 13.734339323029884 -4.874419056226921 2.4796315638967785 1.0377125518153454 1.7345750637825266 0.9076928392158349 0.062290193411345535 0.11094451827428324 1.0150460282525973 0.01589993576075291 0.1531050877801327 1.3353064406858404e-05 4.874419056226921 0.6968625119671812 RSNATNSSYS(ph)PTTGR ddPTM_PC-9_AZD4547_30min_R2 3 RSNATNSSYSPTTGR 15 1 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 RSNATNSS(0.002)YS(0.992)PT(0.003)T(0.003)GR;RSNATNSS(0.015)YS(0.921)PT(0.015)T(0.049)GR;RSNATNSS(0.049)YS(0.644)PT(0.08)T(0.226)GR 115.56 7.2443e-05 8841000.0 16091.3 12867.1 20278.3 33568.1 29080.1 21720.4 16969.3 24494.2 18757.5 23101.5 True False 21207.998680167675 17026.138445145414 20009.396492394168 25829.493166975117 25042.83007406426 20362.219954374494 18479.534826110008 20709.18421072108 19748.98315580478 22292.72351654936 0.9513417534839823 0.7637531785878827 0.8975752324537589 1.1586513037673563 1.1233634174610077 0.913402076657806 0.8289491776270149 0.9289660904531152 0.8858936926725803 1.0 14.444285261907234 -5.531803135421958 24.998421935234433 0.9757147895216762 0.8508266081379696 0.18398316450427243 0.10450694853720208 323.3554016024528 905759.2168121885 0.03147167691715784 0.054607766171931416 2.9389815828940603e-06 5.531803135421958 -0.12488818138370661 RSNATNSSYS(ph)PTTGR ddPTM_PC-9_Lapatinib_30min_R1 2 RSNATNSSYSPTTGR 15 1 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 RSNATNSS(0.078)Y(0.001)S(0.86)PT(0.03)T(0.03)GR;RSNATNSS(0.005)YS(0.331)PT(0.331)T(0.331)GR 71.969 0.0094415 5180600.0 26714.6 17865.3 20804.3 17986.9 18606.4 18040.6 15679.6 14273.1 19653.3 14024.0 True False 26333.64490514234 17823.93399549076 19093.85076092038 19309.716628539438 17512.008133589872 17269.045592692626 16491.412967127984 14936.2803325133 17439.738395576114 16448.029714194618 1.6010212385752476 1.0836516169537764 1.1608594520255775 1.1739835691003884 1.0646872870418664 1.0499157584685948 1.0026375957295315 0.9080893330113162 1.0602934636314314 1.0 14.005627155497532 -1.8705881860409952 0.9687720216325657 1.0336354575821023 199.99999975478542 0.8190955652832712 0.0762042113041644 276.93990199017526 0.9479850366156504 0.026339765692847038 121499.24690007295 0.013471371534723345 1.8705881860409952 198.9663642972033 RSNATNSSYSPT(ph)TGR ddPTM_PC-9_Lapatinib_30min_R1 1 RSNATNSSYSPTTGR 15 1 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 RSNATNSSYS(0.067)PT(0.576)T(0.357)GR 88.28299999999999 0.0041573999999999995 2503900.0 6687.7 5009.0 3888.5 6451.2 6430.7 5276.6 4828.3 3852.6 6465.7 3843.8 True False 6592.332171626023 4997.40196825204 3568.802540044071 6925.642768572329 6052.4588692426405 5050.932118355372 5078.285748946661 4031.605860607772 5737.464779160573 4508.195708458446 1.4622994647852672 1.1085148674614387 0.7916254685545595 1.536233831991406 1.3425457235334284 1.120388830697528 1.1264563646646022 0.8942836827255574 1.2726742914899916 1.0 12.13833443138202 -6.955865403252326 7.776195072755329 1.072671129359017 1.2315733472544539 0.13340157381400342 0.21144272258151284 0.5611102143949329 84.58045656879962 0.07762332729793356 0.0682010586558224 1.1069668024865931e-07 6.955865403252326 0.1589022178954369 RSNATNSSYSPTT(ph)GR ddPTM_PC-9_AZD4547_30min_R2 1 RSNATNSSYSPTTGR 15 1 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 RSNATNSSYS(0.348)PT(0.164)T(0.488)GR 101.54 0.0014038 3808100.0 10327.0 8768.1 13274.0 17398.0 17434.0 10138.0 9889.8 13925.0 9149.5 13242.0 True False 13610.77118505601 11602.21685545923 13097.97808692247 13387.159896420488 15013.590032745287 9504.069257354775 10769.973040918754 11773.211214666784 9633.123890925539 12778.401610551107 1.065138786514396 0.9079552520777948 1.0250091119461677 1.0476396269598172 1.1749192497087106 0.7437604128443794 0.8428263071670876 0.9213367660119292 0.7538598476175207 1.0 13.641419767262535 -6.768170147453836 24.999779701776003 0.8468445763422374 1.035699451124103 0.5178939444070737 0.09225978570179606 134.42748493088925 499294.63009136886 0.03193786103191703 0.028799247773766707 1.7054141126833729e-07 6.768170147453836 0.1888548747818657 RSNATNSSYSPTT(ph)GR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSNATNSSYSPTTGR 15 1 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 RSNATNSSYS(0.14)PT(0.226)T(0.634)GR;RSNATNS(0.001)SYS(0.015)PT(0.078)T(0.906)GR 80.541 0.0082692 4878300.0 14983.2 7712.45 11879.3 14185.9 16660.6 15648.2 14094.7 15087.1 10597.64 10358.5 True False 17519.559828310714 8478.091066193627 12162.547564496123 13391.110014308331 13396.075029117806 14827.580844918282 12759.547979208815 14691.079611103807 10752.610436234861 12236.414052159113 1.4317560482696636 0.6928574850487075 0.993963387692822 1.0943655516417796 1.0947713089811693 1.21175867224777 1.0427522250244055 1.2006033424891804 0.8787386885079755 1.0 13.578893209872195 -4.7119250172675695 24.47141921287498 1.0396139862610825 1.431765319939504 0.41141926484579494 0.145387578669609 15438.873320505692 7629430.724942037 0.03653074752966561 38.86428781979179 1.9412210084697644e-05 4.7119250172675695 0.3921513336784215 RSNS(ph)SEALLVDR ddPTM_PC-9_AZD4547_30min_R2 2 RSNSSEALLVDR 12 1 Q96HB5-2;Q96HB5;Q96HB5-5;Q96HB5-3;Q96HB5-4 Q96HB5-2 CCDC120 Coiled-coil domain-containing protein 120 1 RS(0.004)NS(0.741)S(0.254)EALLVDR;RS(0.033)NS(0.74)S(0.227)EALLVDR 125.33 0.00013576 4756100.0 8929.7 11027.7 20044.6 22650.0 19276.5 15542.6 13879.5 20705.3 13698.7 14788.599999999999 True False 11769.158850701522 14592.188366572891 19778.79550709103 17428.392439011623 16600.290711610327 14570.718764979518 15114.748611845745 17505.771645460678 14422.785315549672 14270.85561529951 0.82469889458373 1.0225167123776997 1.3859572292138225 1.221257709336431 1.1632302336387927 1.0210122754909334 1.0591340154574553 1.2266798934391205 1.0106461521541346 1.0 13.800784214359238 -8.424294649053007 10.363654377913425 1.000042559268575 1.1215252320066484 0.0858619795572706 0.14302893624382693 1.134425041248343 109.0956423846336 0.14557686472899947 0.03759781834908262 3.764483092687486e-09 8.424294649053007 0.12148267273807334 RSNS(ph)SGNLHMAGLTASPTPPSSSIITY ddPTM_PC-9_Lapatinib_30min_R1 1 RSNSSGNLHMAGLTASPTPPSSSIITY 27 1 Q9UKI8-5;Q9UKI8;Q9UKI8-2;Q9UKI8-4;Q9UKI8-3 Q9UKI8-5 TLK1 Serine/threonine-protein kinase tousled-like 1 1 RS(0.013)NS(0.778)S(0.209)GNLHMAGLTASPTPPSSSIITY 62.765 0.0003673 4727300.0 8024.6 7602.8 8961.9 6053.4 10091.0 10170.0 8876.5 9824.6 10726.0 9639.2 True False 7910.167732468587 7585.1961837146355 8225.087175934414 6498.587229550428 9497.467219669325 9735.052807427908 9336.08173695193 10281.086782465634 9517.924930212715 11305.322876573358 0.6996852561247819 0.6709402523507323 0.7275411118932532 0.5748254428908578 0.8400881003893986 0.8611034743289526 0.8258129236006123 0.9094023138224452 0.841897664854451 1.0 13.464714575157636 -6.402839295779248 5.715365944529573 0.8752723909930785 0.6734012615024961 0.7606737817008733 0.05833042884754148 0.11339577865737711 4.863192565125793 0.017338739717627866 0.019641060943788466 3.9551294668328074e-07 6.402839295779248 -0.2018711294905824 RSNS(ph)TTQVSQPR ddPTM_PC-9_AZD4547_30min_R2 4 RSNSTTQVSQPR 12 1 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 RS(0.028)NS(0.91)T(0.031)T(0.031)QVSQPR;RS(0.058)NS(0.452)T(0.452)T(0.038)QVSQPR;RS(0.34)NS(0.645)T(0.013)T(0.001)QVSQPR;RSNS(0.984)T(0.016)TQVSQPR 133.25 2.9015999999999998e-05 29769800.0 9305.4 7878.32 14798.6 22721.3 17338.1 15507.800000000001 13192.7 18084.100000000002 15130.1 18185.899999999998 True False 12264.323635656068 10424.832871055485 14602.360894766534 17483.255325585633 14931.004092390796 14538.094814480806 14366.824742353629 15289.617876276874 15929.846197288654 17549.217176357146 0.6988530321556992 0.5940340680893815 0.8320804710559564 0.9962413223274496 0.8508074145042955 0.8284184227924982 0.8186590090017841 0.8712421598426353 0.9077240333403499 1.0 14.099119056747304 -5.375799392533656 4.85524499834012 0.8847064269872054 0.6483334819423859 0.6982498076059812 0.06424070381742314 0.11746140986961501 4.162041078726138 0.01703250620839838 0.03692128540475073 4.209210135367239e-06 5.375799392533656 -0.23637294504481943 RSNS(ph)TTQVSQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RSNSTTQVSQPR 12 1 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 RS(0.244)NS(0.603)T(0.076)T(0.076)QVSQPR;RS(0.425)NS(0.563)T(0.012)TQVSQPR;RS(0.13)NS(0.809)T(0.017)T(0.017)QVS(0.027)QPR 133.87 2.5521999999999997e-05 13649000.0 12325.900000000001 10488.699999999999 11873.7 15273.1 16882.3 16685.3 14300.8 18008.0 17833.3 13503.3 True False 14412.431422378058 11529.948818596567 12156.814039258004 14417.397723058288 13574.334505604576 15810.293495208065 12946.124695174029 17535.309081053176 18094.078275211024 15951.34139793601 0.9035247295404839 0.7228200143775031 0.7621186040711917 0.9038360701704871 0.8509838869952967 0.9911576149485337 0.8116010040916788 1.099299967545182 1.134329572906782 1.0 13.961390129356408 -7.286616518140378 0.7907028197547699 1.0842713324036084 0.8064240309619789 0.5479124560495722 0.08775981496777199 0.4826800970169479 0.5878756109817312 0.0727061519601321 0.04355907937678493 5.168725661076649e-08 7.286616518140378 -0.2778473014416295 RSNS(ph)TTQVSQPR ddPTM_PC-9_Lapatinib_30min_R1 2 RSNSTTQVSQPR 12 1 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 RS(0.005)NS(0.972)T(0.023)T(0.001)QVSQPR;RSNS(0.867)T(0.132)T(0.001)QVSQPR 106.6 0.0007571 18731100.0 12963.8 7740.4 12546.099999999999 7790.4 8810.5 8125.5 9040.2 7873.299999999999 10043.099999999999 8470.8 True False 12778.933834730247 7722.477579368762 11514.60808734652 8363.332004012562 8292.283712109458 7777.991306465639 9508.257321961677 8239.122260894765 8911.940319468515 9934.966493368485 1.2862583727141998 0.7773028308171404 1.1589981803192224 0.841807771530485 0.8346564346889841 0.7828905423744901 0.9570497624031613 0.8293054905010818 0.8970277177499458 1.0 13.27829938651724 -5.780551260720355 24.98381138846702 0.8680047752397303 1.0444981211505382 0.30250903495387704 0.13404707887025252 290.78780172948507 380128.4647326244 0.035177120831060234 0.052268263665517956 1.6574816891413384e-06 5.780551260720355 0.1764933459108079 RSNT(ph)LDIMDGR ddPTM_PC-9_Lapatinib_30min_R1 2 RSNTLDIMDGR 11 1 H0Y9X0;A0A286YEZ9;A0A2C9F2R7;O94915 H0Y9X0 FRYL Protein furry homolog-like 1 RS(0.05)NT(0.95)LDIMDGR;RS(0.118)NT(0.882)LDIMDGR 111.88 0.001492 8175300.0 20505.8 15088.4 15732.3 15197.0 13962.5 18626.5 15837.9 15485.4 19786.5 13929.9 True False 20213.38353169682 15053.463736828537 14438.85102243419 16314.638075705865 13141.253201331181 17829.88801549223 16657.90896656014 16204.908216232045 17557.936008917935 16337.664654574983 1.2372260025570139 0.9213962983756778 0.8837769245306994 0.9985905832102712 0.8043532217838294 1.0913363930810873 1.0196015966024543 0.9918742096162585 1.0746906843874557 1.0 13.995914155441115 RSNVSSPATPTASSS(ph)SSTTPTRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSNVSSPATPTASSSSSTTPTRK 23 2 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 RSNVSSPATPT(0.002)AS(0.052)S(0.052)S(0.157)S(0.157)S(0.157)T(0.157)T(0.157)PT(0.111)RK 61.086999999999996 0.001462 4888100.0 21381.0 19423.0 22357.0 32472.0 32893.0 35194.0 31458.0 32877.0 27951.0 21291.0 True False 25000.381006000796 21351.18707786486 22890.075669394646 30652.699115644435 26447.852774376213 33348.364684503875 28478.070503802926 32014.013586060944 28359.730496903172 25150.88976053673 0.9940157681907503 0.8489237271981592 0.9101099757238236 1.2187520762681079 1.051567281562917 1.325931806071906 1.1322887887841941 1.2728779733388547 1.1275835871779498 1.0 14.61832181856267 -5.755524545287108 24.99107417033081 1.1737362731153722 0.9108071288834416 0.565700985198777 0.09732945957454317 89.641325746736 378743.22973057546 0.024910248043559277 0.04172487577659956 1.7558016576776786e-06 5.755524545287108 -0.2629291442319306 RSNVSSPATPTASSSSS(ph)TTPTR ddPTM_PC-9_AZD4547_30min_R2 1 RSNVSSPATPTASSSSSTTPTR 22 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 RSNVSSPATPTAS(0.001)S(0.001)S(0.007)S(0.088)S(0.272)T(0.272)T(0.272)PT(0.088)R 89.891 0.00068045 0.0 5985.0 5481.4 5818.3 10268.0 9032.3 6967.9 6390.4 6756.4 6765.3 7821.3 True False 7888.105504266507 7253.1553553807835 5741.145540390314 7900.871239018598 7778.321053846811 6532.19611149362 6959.133220154831 5712.353626626543 7122.899946366315 7547.478667618439 1.0451312089306706 0.9610037569896799 0.7606706548270241 1.0468225995677667 1.030585364516335 0.8654805663140502 0.9220474183003876 0.7568558823670105 0.9437456215578682 1.0 12.881779058737578 -6.788973559606932 24.988525521415927 0.8839557108323005 0.9611743638768664 0.10819025568248386 0.09715545748540623 479.2181044653078 434909.00148790405 0.034803434418499424 0.030700815955347988 1.625647724211318e-07 6.788973559606932 0.07721865304456588 RSNVSSPATPTASSSSS(ph)TTPTRK ddPTM_PC-9_AZD4547_30min_R2 1 RSNVSSPATPTASSSSSTTPTRK 23 2 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 RSNVSSPATPT(0.012)AS(0.022)S(0.148)S(0.131)S(0.102)S(0.168)T(0.168)T(0.168)PT(0.08)RK 47.507 0.014879 4816100.0 8692.4 6606.3 12398.0 14748.0 14413.0 9614.2 8725.8 13913.0 9125.3 11628.0 True False 11456.402386848153 8741.657281762336 12233.59441929071 11348.076454328628 12412.003736489489 9013.02255415864 9502.379295885552 11763.065538934216 9607.644728330819 11220.907259287736 1.0209871735073377 0.7790508449775055 1.090250024940252 1.0113332364400063 1.106149747937348 0.8032347426005512 0.8468458990265935 1.0483167953462698 0.8562270863060923 1.0 13.453901708398002 -6.763401997343231 24.99965403670555 0.9099397886611639 0.9946637203417925 0.1505015790623091 0.10702173755200538 117.19269739322286 1492774.6349767034 0.03748178714850851 0.03471644653408148 1.7242411384474585e-07 6.763401997343231 0.08472393168062864 RSNVSSPATPTASSSSSTT(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 1 RSNVSSPATPTASSSSSTTPTR 22 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 RSNVSSPATPTAS(0.003)S(0.002)S(0.12)S(0.192)S(0.192)T(0.192)T(0.217)PT(0.082)R 97.78399999999999 0.0010255999999999998 0.0 4193.4 4940.6 4201.5 7034.4 5350.3 7042.2 4355.4 6475.1 5019.7 6084.5 True False 5526.813971861517 6537.552331301178 4145.78536478867 5412.727760396615 4607.50319790049 6601.850120748055 4743.022162472202 5474.522077995613 5285.031094079344 5871.483506977664 0.9412977087125354 1.113441317433994 0.7060882245282345 0.9218671489009781 0.7847255625303109 1.1243921766794414 0.8078064354324763 0.9323916300692486 0.9001185284432154 1.0 12.519509349795745 RSPGGGS(ph)EANGLALVSGFK ddPTM_PC-9_Lapatinib_30min_R1 1 RSPGGGSEANGLALVSGFK 19 1 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 RS(0.005)PGGGS(0.995)EANGLALVSGFK 89.344 0.000487 5906700.0 27979.0 31424.0 30093.0 27118.0 27552.0 30019.0 23447.0 35253.0 30803.0 24697.0 True False 27580.0143292798 31351.23965868479 27618.869702339278 29112.34818299611 25931.445529316137 28735.15734770683 24660.970932947886 36890.98307740377 27333.64177003003 28965.84354331604 0.9521564351487348 1.0823520334148593 0.9534978555358667 1.0050578412971465 0.8952422010613221 0.9920359234398184 0.8513810721952367 1.2736029255366352 0.9436508116587322 1.0 14.822065059336945 -7.73324626054577 24.99997386387754 1.0814708874221373 0.9662829784166759 0.20759926164265907 0.09838584373234459 292.56233742229455 259426.98544684966 0.04346068504260224 0.025085381043007608 1.848220314594411e-08 7.73324626054577 -0.11518790900546139 RSPS(ph)IVASNQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSPSIVASNQGR 12 1 Q8TED9;Q8TED9-4 Q8TED9 AFAP1L1 Actin filament-associated protein 1-like 1 1 RS(0.225)PS(0.775)IVASNQGR 71.316 0.012694 4722200.0 6100.1 7535.6 7341.6 7776.2 13670.0 8674.2 7495.2 11459.0 8082.3 5696.0 True False 7132.726447533115 8283.684566954567 7516.651587173052 7340.524724780551 10991.461630916085 8219.309681943616 6785.200395451193 11158.213391814106 8200.48834729063 6728.639710488813 1.060054744261964 1.2311083552358588 1.1171131031812955 1.0909374020038423 1.6335339836642244 1.2215410596485201 1.0084059612932181 1.6583163717950802 1.2187438620777173 1.0 12.716099157805196 RSPS(ph)PGNSPSGR ddPTM_PC-9_Lapatinib_30min_R1 1 RSPSPGNSPSGR 12 1 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 RS(0.149)PS(0.851)PGNSPSGR 67.648 0.016681 1499700.0 0.0 858.21 577.78 552.32 659.43 491.55 0.0 0.0 750.04 0.0 True False 0.0 856.2228674732658 530.2771586952977 592.9394552855078 620.6436238892618 470.52755235901566 0.0 0.0 665.5625969286543 0.0 0.0 RSPS(ph)PLGTSVR ddPTM_PC-9_AZD4547_30min_R2 2 RSPSPLGTSVR 11 1 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 RS(0.025)PS(0.972)PLGT(0.003)S(0.001)VR;RS(0.001)PS(0.982)PLGT(0.015)S(0.002)VR 104.41 0.0039461 16312200.0 66852.0 40056.0 70408.0 110295.0 84983.0 62931.0 66402.0 91982.0 67718.0 81458.0 True False 88109.5453920176 53003.31866222728 69474.34391623006 84868.19179076314 73184.5773633585 58995.914621680146 72311.64936228095 77768.29543608475 71297.43523096296 78606.18021388556 1.1208984478354451 0.6742894581317461 0.8838280110697659 1.0796630946808357 0.9310282876514926 0.7505251426942978 0.9199232066171218 0.989340726447705 0.9070207334456951 1.0 16.26235512477391 -8.438715234729155 1.029843058317925 0.9926439972328525 0.9037374113524647 0.031324675745818986 0.12735393925894414 2.0351511148461654 4.727225264492596 0.12135364526165045 0.040393702066355834 3.641537321056162e-09 8.438715234729155 -0.0889065858803878 RSPS(ph)PLGTSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSPSPLGTSVR 11 1 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 RS(0.011)PS(0.953)PLGT(0.018)S(0.018)VR 86.49799999999999 0.015991 7725300.0 16525.0 19132.0 25533.0 21774.0 28886.0 22068.0 20154.0 26514.0 17975.0 17209.0 True False 19322.356116372626 21031.298521016877 26141.80355444173 20554.073372260464 23225.99565988603 20910.71523150627 18244.86721767577 25818.03559390516 18237.850369640953 20328.855473630945 0.9504891281969182 1.0345539889492101 1.285945664198897 1.0110787298833255 1.1425136889783607 1.0286223569561046 0.8974861984405188 1.2700191423660994 0.8971410315400055 1.0 14.311241372449864 -6.84889212513458 13.851951227043488 1.027895168137866 1.0891783103151096 0.06016411226041485 0.1278224012218389 3.0471497696042293 471.9845437048441 0.04425179050466136 0.03902824344344581 1.4161454941501353e-07 6.84889212513458 0.06128314217724351 RSPS(ph)PLGTSVR ddPTM_PC-9_Lapatinib_30min_R1 2 RSPSPLGTSVR 11 1 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 RS(0.007)PS(0.989)PLGT(0.004)SVR;RS(0.001)PS(0.964)PLGT(0.035)S(0.001)VR 103.83 0.0040512000000000005 16839600.0 78515.0 71938.0 90245.0 66166.0 82903.0 60012.0 59909.0 63961.0 68964.0 52139.0 True False 77395.36170211258 71771.4319808577 82825.40445577401 71032.06836330537 78026.8085335691 57445.42665480474 63010.7948830117 66932.8615611103 61196.54809688509 61151.1566791495 1.2656401923547231 1.1736725170617968 1.354437249492203 1.1615817626475893 1.2759661921517444 0.9394004917390502 1.0304105155953047 1.094547759943389 1.0007422822428977 1.0 15.900092167255352 -6.753830486707467 24.999843314844085 1.0200163339641428 1.2435325447582803 0.7795918195911465 0.06194431056764321 80.85165544315412 265646.65282931266 0.020022037237387238 0.01965608687089354 1.7626639129881368e-07 6.753830486707467 0.22351621079413753 RSPS(ph)PSPTPEAK ddPTM_PC-9_Lapatinib_30min_R1 2 RSPSPSPTPEAK 12 1 F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 F8VXC8 SMARCC2 SWI/SNF complex subunit SMARCC2 1 RS(0.036)PS(0.793)PS(0.17)PT(0.001)PEAK;RS(0.219)PS(0.728)PS(0.052)PT(0.001)PEAK 65.51100000000001 0.019004 10133000.0 48872.0 38574.0 46662.0 35005.0 39166.0 47032.0 35786.0 39163.0 45595.0 36698.0 True False 48175.07631797287 38484.6842729795 42825.630480528846 37579.38447325681 36862.33288331866 45020.550996946855 37638.823977757216 40982.65595156053 40459.610963364605 43041.200402988725 1.1192781768843894 0.8941359421357397 0.9949915448351456 0.873102611484027 0.856442955544497 1.0459873464361065 0.8744836023472902 0.9521726988988614 0.94002050557482 1.0 15.393430694230437 -4.75379150629019 24.90218785236379 0.9340997601087653 1.1192785255979658 0.45484200518081475 0.059861176713031136 232.2416642858298 756135.2617868354 0.014192675599773216 0.14715366743652034 1.7628221292707125e-05 4.75379150629019 0.18517876548920054 RSPT(ph)SSPTPQR ddPTM_PC-9_AZD4547_30min_R2 1 RSPTSSPTPQR 11 1 A0A0D9SFE4;A0A0D9SFB1;A0A0U1RQP1;Q05193-5;Q05193-3;Q05193-2;Q05193 A0A0D9SFE4 DNM1 Dynamin-1 1 RSPT(0.752)S(0.123)S(0.123)PT(0.001)PQR 78.529 0.015527000000000001 2417600.0 6625.1 4383.8 7705.6 10032.0 8878.0 9351.0 3255.8 6534.0 4346.1 6278.6 True False 8731.743989359398 5800.77762011863 7603.418709250403 7719.277392854952 7645.442945434937 8766.280491766076 3545.559892679663 5524.320436382961 4575.825973260997 6058.788125057104 1.441170050698398 0.9574154930634677 1.25494051818799 1.2740629369313354 1.2618765977004485 1.4468702834336948 0.5851929163880848 0.9117863708645356 0.7552378262472861 1.0 12.564813540272498 -7.259066070153756 24.999906171649982 0.8057031405156305 1.2571501460817764 0.6601627395879213 0.16130335343768681 129.70006707901837 1366240.550260976 0.0617985590968095 0.04555546292686314 5.5072390721936574e-08 7.259066070153756 0.4514470055661459 RSPTDSDVS(ph)LDSEDSGAK ddPTM_PC-9_Lapatinib_30min_R1 1 RSPTDSDVSLDSEDSGAK 18 1 Q8N3V7-2 Q8N3V7-2 SYNPO Synaptopodin 1 RSPTDS(0.001)DVS(0.397)LDS(0.301)EDS(0.301)GAK 54.833999999999996 0.018953 23493000.0 15950.0 9915.4 93039.0 14155.0 30210.0 62410.0 17157.0 15884.0 78076.0 13467.0 True False 15722.550075128234 9892.441500500365 85389.69256092596 15196.00591969576 28433.107195145214 59740.86978481573 18045.305510154252 16622.02862739289 69282.25870327129 15794.75300635045 0.9954286761437051 0.626311883226221 5.406206258913585 0.962092025977617 1.800161558950202 3.782323773014765 1.1424873502547932 1.0523766101761658 4.386409757431194 1.0 13.947157756374693 RSPTGS(ph)TTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSPTGSTTSR 10 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 RS(0.138)PT(0.138)GS(0.439)T(0.138)T(0.138)S(0.008)R 77.74 0.031366000000000005 6105900.0 4858.9 9993.4 7510.7 6335.3 22441.0 19742.0 6459.6 15280.0 20461.0 23509.0 True False 5681.415802350559 10985.47870792023 7689.783572488364 5980.353680319724 18043.847144066418 18706.694766195254 5847.699924545914 14878.916190498254 20760.203416591023 27770.99560285839 0.20458091901342515 0.3955738161144473 0.2768998159971217 0.21534531083589178 0.6497371358990535 0.6736054779494411 0.21056860935673571 0.5357717959872785 0.7475498434940602 1.0 14.761291278908558 -11.045507064171053 0.11859831028539511 1.8783322568258145 8.880024447010649e-17 0.6333228474266976 0.1575627329496641 35.97847792900683 0.7101673334948547 11.280264975646277 2.2451646021246074 9.005191149182057e-12 11.045507064171053 -1.8783322568258145 RSPTS(ph)SPTPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSPTSSPTPQR 11 1 A0A0D9SFE4;A0A0D9SFB1;A0A0U1RQP1;Q05193-5;Q05193-3;Q05193-2;Q05193 A0A0D9SFE4 DNM1 Dynamin-1 1 RS(0.002)PT(0.009)S(0.486)S(0.486)PT(0.017)PQR;RS(0.008)PT(0.016)S(0.485)S(0.485)PT(0.005)PQR 61.423 0.027226 2175900.0 11320.3 13243.8 12390.7 14662.7 16432.3 18546.0 12865.1 9711.9 11383.5 13684.1 True False 13236.603203883387 14558.556938774991 12686.141279991434 13841.19645611479 13212.508775252543 17573.415111632916 11646.424592741902 9456.972915608636 11549.962152033808 16164.919006724005 0.8188474806695569 0.9006266553342565 0.7847946082943237 0.8562490446353221 0.8173569425096798 1.087132889705357 0.7204752827958756 0.5850306402200275 0.7145078887948312 1.0 13.980578658501827 -7.427217658316872 22.90663312588463 0.720261035597213 0.873403650546164 0.16504011459139123 0.12540317546026625 33.61989401018691 8044.671792633112 0.05059545687530741 0.03411140663535441 3.7392313970251034e-08 7.427217658316872 0.15314261494895098 RSQANGAGALSYVS(ph)PNTSK ddPTM_PC-9_AZD4547_30min_R2 1 RSQANGAGALSYVSPNTSK 19 1 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;A0A494C002;A0A494C1N1;A0A494C0Q2;F5H1Z4;A0A494C1K5;A0A494C0P9;A0A494BZU6;A0A494C1G3;A0A494C156;A0A494BZW7 O95453 PARN Poly(A)-specific ribonuclease PARN 1 RSQANGAGALS(0.001)Y(0.019)VS(0.965)PNT(0.011)S(0.004)K 67.01 0.004338399999999999 12130000.0 28611.0 21015.0 29169.0 30260.0 30335.0 25744.0 25153.0 27920.0 29260.0 28000.0 True False 37708.70285423041 27807.687779276675 28782.200001313984 23284.024512339587 26123.50887021501 24134.223610311823 27391.568272182423 23605.60553777354 30806.623864526075 27019.728522536698 1.395598879640046 1.0291623676412127 1.065229059474348 0.8617416156834727 0.9668309157298095 0.893207479497134 1.013761787034077 0.873643327618355 1.1401529752170083 1.0 14.721725558981456 -4.115027372183783 1.3648748380448985 0.9627389525257133 2.964601578225882 0.6939645734846496 0.08266558989084398 3.5036060760339134 1.57652240219092 0.022216787675551002 15.139617338726104 7.673131265603438e-05 4.115027372183783 2.0018626257001686 RSQANGAGALSYVSPNT(ph)SK ddPTM_PC-9_AZD4547_30min_R2 1 RSQANGAGALSYVSPNTSK 19 1 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;A0A494C002;A0A494C1N1;A0A494C0Q2;F5H1Z4;A0A494C1K5;A0A494C0P9;A0A494BZU6;A0A494C1G3;A0A494C156;A0A494BZW7 O95453 PARN Poly(A)-specific ribonuclease PARN 1 RSQANGAGALSYVS(0.145)PNT(0.569)S(0.285)K 167.89 2.3401e-27 0.0 8936.1 8388.7 8366.5 10586.0 10609.0 10216.0 7592.6 9498.8 8148.4 9411.2 True False 11777.59391757325 11100.183225030602 8255.554743426013 8145.56125206963 9136.123474669886 9577.1919050243 8268.32669118484 8030.97872070929 8579.107788711695 9081.716752546334 1.2968466467830595 1.2222560477806501 0.909030194220858 0.8969186635099334 1.0059907970713025 1.0545574329147673 0.9104365305014126 0.8843018274554272 0.9446570535583245 1.0 13.148749326261466 -5.18627781779397 4.531453207747844 0.9488672195113017 1.2761510535758156 0.8439291943429384 0.05334562775230381 0.0829311307876508 3.1771312306207085 0.01501685125869252 0.042952184595694776 6.512116812560991e-06 5.18627781779397 0.3272838340645139 RSQANGAGALSYVSPNT(ph)SK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSQANGAGALSYVSPNTSK 19 1 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;A0A494C002;A0A494C1N1;A0A494C0Q2;F5H1Z4;A0A494C1K5;A0A494C0P9;A0A494BZU6;A0A494C1G3;A0A494C156;A0A494BZW7 O95453 PARN Poly(A)-specific ribonuclease PARN 1 RSQANGAGALSYVS(0.127)PNT(0.679)S(0.194)K 86.74799999999999 0.0041488 2645400.0 7891.7 4526.0 8304.4 7443.0 7759.0 7938.3 9462.5 7556.5 9560.7 7321.2 True False 9227.608941820148 4975.311368708047 8502.408390612376 7025.992840531581 6238.679648447537 7522.00157342153 8566.14349743261 7358.149881773566 9700.507150432619 8648.475605412688 1.0669636318387725 0.5752818873182952 0.9831106403643094 0.8123966767200373 0.7213617674475523 0.8697488339695207 0.9904801595406535 0.8508031030541885 1.1216435812528063 1.0 13.078230148010222 -7.679261510482141 1.1518270039546048 1.0328090755945942 0.8259393921170396 0.2294690697747951 0.1389179693234145 0.7087754488696674 1.7172654618681549 0.10915138149327655 0.045140890174968876 2.0928518653174198e-08 7.679261510482141 -0.20686968347755463 RSQS(ph)FNSIDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSQSFNSIDK 10 1 Q8IVL0-3;Q8IVL0-2;Q8IVL0;F8VZV4;H0YHX7;A0A1B0GTC4 Q8IVL0-3 NAV3 Neuron navigator 3 1 RS(0.144)QS(0.853)FNS(0.003)IDK 55.335 0.041446 3769100.0 43487.0 43155.0 37022.0 44601.0 39496.0 43402.0 42979.0 42681.0 42578.0 30735.0 True False 50848.49019259892 47439.14319854079 37904.74488671688 42102.15056839299 31757.042324408303 41125.92271514567 38907.71797898611 41560.66897425757 43200.622700337815 36307.01220187388 1.4005143113917407 1.3066110462290357 1.0440061736823538 1.1596148516517153 0.8746806855885888 1.1327267164391754 1.071630950039398 1.144700884313266 1.189869947439744 1.0 15.147960591458563 -5.1344483352514985 3.482272382284741 1.079529553696727 1.3862026365185796 0.6205442072194534 0.0875250948070554 0.15643051471064118 3.3862047317276205 0.022849347421785907 0.07615763303683248 7.337559986596011e-06 5.1344483352514985 0.30667308282185246 RSQS(ph)IEQESQEK ddPTM_PC-9_AZD4547_30min_R2 2 RSQSIEQESQEK 12 1 A0A0A0MRN0;Q5VTL8 A0A0A0MRN0 PRPF38B Pre-mRNA-splicing factor 38B 1 RS(0.013)QS(0.987)IEQESQEK;RS(0.007)QS(0.993)IEQESQEK 85.473 0.0044222 31741000.0 50781.0 47879.0 60417.0 65190.0 61135.0 54018.0 55010.0 57695.0 59434.0 55110.0 True False 66928.3016895835 63354.950425124356 59615.83110423346 50161.452675459965 52647.460516914245 50640.245920673726 59905.78343150935 48779.56344920648 62575.55990308419 53180.615674178494 1.2585093429461762 1.19131660327667 1.1210067869368339 0.9432281300160941 0.989974633604644 0.9522312834986935 1.1264590052611259 0.9172433006053197 1.176661065499235 1.0 15.698612858981633 -5.407585681335102 2.5341330375709026 1.0130965062404342 1.233783489384024 0.5343408075809376 0.07838427391444282 0.2098744647970762 2.5792249268628678 0.020695835401079894 0.054434506247790435 3.912139374764709e-06 5.407585681335102 0.2206869831435898 RSQS(ph)IEQESQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RSQSIEQESQEK 12 1 A0A0A0MRN0;Q5VTL8 A0A0A0MRN0 PRPF38B Pre-mRNA-splicing factor 38B 1 RS(0.006)QS(0.994)IEQESQEK;RS(0.042)QS(0.958)IEQESQEK;RS(0.078)QS(0.922)IEQESQEK 99.069 0.0015865999999999999 30779300.0 79797.0 90345.0 97080.0 114599.0 125647.0 103138.0 111502.0 106004.0 101202.0 84829.0 True False 93305.05603740901 99313.85453069583 99394.75537795028 108178.38956497097 101027.37231453632 97729.26171592779 100939.72335542715 103221.50732052224 102681.88779462599 100207.82619400567 0.9311154585547773 0.9910788239076349 0.9918861545356621 1.079540328073119 1.0081784642144016 0.9752657594499725 1.0073037924204093 1.0300743089734528 1.0246893051629566 1.0 16.612635661316894 -4.730994842589692 1.7521957043386185 1.0162077960463618 0.8958011217349066 0.4846847099700089 0.026189470769279515 0.9549353322765282 2.6910787106700385 0.00759281800812847 0.20167231659041396 1.857826517349309e-05 4.730994842589692 -0.12040667431145524 RSQS(ph)IEQESQEK ddPTM_PC-9_Lapatinib_30min_R1 2 RSQSIEQESQEK 12 1 A0A0A0MRN0;Q5VTL8 A0A0A0MRN0 PRPF38B Pre-mRNA-splicing factor 38B 1 RS(0.001)QS(0.999)IEQESQEK;RS(0.002)QS(0.998)IEQESQEK 78.902 0.0073203 40873000.0 82814.0 73194.0 85740.0 70408.0 75101.0 69285.0 67980.0 73882.0 77843.0 59064.0 True False 81633.05717377242 73024.52379002605 78690.78816597098 75586.03919420263 70683.70683424688 66321.84206122348 71499.67177130534 77314.82743950133 69075.50161687008 69273.13370216715 1.1784230452854279 1.0541536074286408 1.1359495948933693 1.0911306469716988 1.020362484800303 0.9573963023871209 1.0321414370932165 1.1160867613107937 0.9971470601265597 1.0 16.08000831791731 -6.153878949186077 3.8197203328736515 1.0237535709531704 1.1155652705407861 0.49233357275013445 0.04744302977490295 0.23348302710027558 6.108229651931125 0.014814835187517273 0.019560703920508214 7.016508421654204e-07 6.153878949186077 0.0918116995876157 RSQS(ph)TTFNPDDMSEPEFK ddPTM_PC-9_AZD4547_30min_R2 1 RSQSTTFNPDDMSEPEFK 18 1 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 RS(0.131)QS(0.487)T(0.191)T(0.191)FNPDDMSEPEFK 68.406 0.004474199999999999 6826300.0 17392.0 16083.0 20701.0 30817.0 29314.0 25174.0 23219.0 27105.0 25351.0 28770.0 True False 22922.294223926983 21281.515229793324 20426.49121420687 23712.616767903797 25244.257096472145 23599.865800419113 25285.44601883687 22916.54506093668 26691.002104907762 27762.771056906455 0.8256486420949208 0.7665486700218705 0.7357511673578218 0.8541156327406622 0.9092844890997368 0.8500544038650008 0.9107680918092896 0.8254415603530256 0.9613954619370723 1.0 14.760863952888414 -6.693693372128401 0.16038199056496286 1.0559146486577937 0.6496439689956622 0.6465216133784109 0.04659240528381202 6.011352956498506 0.41937256929670874 0.29921954407837614 0.6771883714367928 2.0244480089412242e-07 6.693693372128401 -0.4062706796621315 RSQS(ph)YIPTSGCR ddPTM_PC-9_AZD4547_30min_R2 2 RSQSYIPTSGCR 12 1 A0A087WZ32;A0A087X038;A8K727;Q9HB19;E5RHB5 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 RS(0.092)QS(0.908)YIPTSGCR;RS(0.001)QS(0.965)YIPT(0.023)S(0.011)GCR 109.55 0.0019077000000000002 22289000.0 16119.2 13321.9 21306.5 34156.0 33521.0 25430.0 15939.4 22072.0 22812.3 24653.2 True False 21244.770299811633 17627.94365104668 21023.961888580205 26281.86190493955 28867.187764578095 23839.858079949885 17357.975721290673 18661.27956410235 24018.11160576653 23790.098971850057 0.8930089078212656 0.74097815532021 0.8837273822802116 1.1047394941920126 1.2134118398891727 1.0020915889487767 0.7296302441544998 0.7844137002617582 1.0095843499510562 1.0 14.53807365324189 -5.527314873306618 24.732576625891195 0.9711395440413336 0.8158333171891715 0.18868305724855106 0.13585522435235434 195.782045127426 1091532.287932961 0.04232295012683807 0.07369156343037733 2.9695122876097632e-06 5.527314873306618 -0.1553062268521621 RSQS(ph)YIPTSGCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSQSYIPTSGCR 12 1 A0A087WZ32;A0A087X038;A8K727;Q9HB19;E5RHB5 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 RS(0.015)QS(0.984)YIPT(0.002)SGCR 101.45 0.0039898 7301100.0 7662.6 6042.4 5464.3 8169.8 8600.9 10260.0 6893.7 8199.2 8671.8 7765.6 True False 8959.726836751399 6642.249539169574 5594.589635473148 7712.072592848973 6915.615387077255 9721.947538302267 6240.678829934072 7983.979687770505 8798.608669566202 9173.441807544219 0.9767028586133221 0.7240738730916679 0.6098681119743049 0.8406956466989937 0.7538735768062395 1.0597927955794038 0.680298513999593 0.8703363312562246 0.959139312611134 1.0 13.163247408564617 RSQS(ph)YIPTSGCR ddPTM_PC-9_Lapatinib_30min_R1 1 RSQSYIPTSGCR 12 1 A0A087WZ32;A0A087X038;A8K727;Q9HB19;E5RHB5 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 RS(0.079)QS(0.92)Y(0.001)IPTSGCR 53.981 0.039902999999999994 16322000.0 23526.0 17063.0 26287.0 17345.0 18669.0 16706.0 18286.0 17817.0 21706.0 12118.0 True False 23190.514925859974 17023.491671847594 24125.784330754414 18620.60916122382 17570.926124666206 15991.523323588068 19232.759605914838 18644.84286415632 19261.241705686843 14212.580153779962 1.6316892974350088 1.1977763001266202 1.6974950409928171 1.3101498081100709 1.2362938984019072 1.1251667994523133 1.3532208365980414 1.3118548963256018 1.3552248428702192 1.0 13.794880864964934 -1.5228787849176093 0.03342717659604669 4.699323783488868e-11 3.322061158636342 0.38261881065848224 0.15801506438186264 1272.0068620604904 3.26540927396024 98.32847190222036 263.0438451187853 0.029999997261954393 1.5228787849176093 3.322061158589349 RSQVS(ph)SPCSR ddPTM_PC-9_AZD4547_30min_R2 1 RSQVSSPCSR 10 1 H0YCY5;E9PNY0;E9PM53;E5KP25;Q9UIF7-6;Q9UIF7-5;Q9UIF7-4;Q9UIF7-3;Q9UIF7-2;Q9UIF7 H0YCY5 MUTYH A/G-specific adenine DNA glycosylase 1 RS(0.132)QVS(0.434)S(0.434)PCSR 84.18799999999999 0.018661 445900.0 2299.4 694.82 3606.0 4605.7 2748.5 3384.3 2130.3 2035.8 1115.1 2273.9 True False 3030.5613695088377 919.4069770543433 3558.1820838814574 3543.927022355667 2366.918217563407 3172.6791859997797 2319.8925730620676 1721.213888030063 1174.0419094782303 2194.2914531212923 1.3811115953616757 0.4189994796482133 1.6215631149727558 1.615066684653295 1.0786708457513974 1.4458786600507283 1.0572399440202498 0.7844053193488516 0.5350437417090617 1.0 11.099539446705316 -7.646542197146859 3.293266803244478 0.7385079954735092 1.2469902749369333 0.2878472399252191 0.3407496878890798 0.3237802615719141 6.888919086058034 0.18775635843577876 0.09787513162370737 2.2566167262742353e-08 7.646542197146859 0.5084822794634241 RSRS(ph)ESETSTMAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSRSESETSTMAAK 14 2 A0A087WVF1;Q96B23-2;Q96B23 A0A087WVF1 C18orf25 Uncharacterized protein C18orf25 1 RS(0.278)RS(0.705)ES(0.009)ET(0.004)S(0.004)T(0.002)MAAK 64.244 0.037586 1600500.0 4431.8 1983.8 3203.0 7932.8 7508.0 14499.0 10627.0 14589.0 12352.0 9445.2 True False 5182.016207960071 2180.7385535225403 3279.3716674451434 7488.350934484602 6036.861296628964 13738.646915969248 9620.333627182701 14206.054208323238 12532.624632311821 11157.539991837935 0.46444074695236287 0.19544976357851407 0.2939152958308103 0.6711471292025436 0.5410566577440101 1.2313329753708673 0.8622271248160666 1.2732245834400215 1.123242636054166 1.0 13.445731357183167 -6.440643377500169 1.208354060256364 1.1215020921904382 0.30999364814778385 0.7961475380098492 0.166772602000729 0.18480668688391344 0.5614220600983391 0.06948750126302125 0.08503449820716914 3.625405777401903e-07 6.440643377500169 -0.8115084440426543 down RSRVDSEASGNFEEPTAVKAGSS(ph)ADLT(ph)EEGGK ddPTM_PC-9_AZD4547_30min_R2 1 RSRVDSEASGNFEEPTAVKAGSSADLTEEGGK 32 3 K7EQN6 K7EQN6 ZNF536 2 RS(0.005)RVDS(0.005)EAS(0.007)GNFEEPT(0.034)AVKAGS(0.157)S(0.797)ADLT(0.995)EEGGK 49.793 0.0034552 8617100.0 4471.3 4991.2 5150.8 4083.9 6465.0 4463.2 5673.0 5027.3 4536.9 5513.6 True False 5893.080391182428 6604.507791764254 5082.497026527065 3142.4199506260293 5567.446344023075 4184.115398444056 6177.886009942783 4250.446300861351 4776.71127173508 5320.57054220923 1.1076030933959722 1.2413157084130872 0.9552541379174515 0.5906171012481719 1.0464002497204625 0.7864035191809918 1.161132243418687 0.7988703969135729 0.8977817761911816 1.0 12.377365243599352 -5.36981159721023 5.364085356784872 0.8930525139246617 1.171846779200201 0.34082899024801827 0.15120823280805515 0.2238103346496255 9.138871731477245 0.03859870733872953 0.08267718640552896 4.26764614882245e-06 5.36981159721023 0.2787942652755393 RSS(ph)AIGIENIQEVQEK ddPTM_PC-9_AZD4547_30min_R2 1 RSSAIGIENIQEVQEK 16 1 J3KPC5;P47736-3;F2Z357;P47736;A0A0A0MQY8;X6R8W7;P47736-2;P47736-4 J3KPC5;P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 RS(0.238)S(0.762)AIGIENIQEVQEK 181.51 1.1444e-06 81935000.0 139430.0 114470.0 140540.0 168200.0 196570.0 152670.0 147260.0 209340.0 166350.0 182520.0 True False 183765.83967583615 151470.18891714502 138676.34777279518 129424.08866409515 169279.64854518403 143123.5207654717 160365.85471957922 176991.313154639 175142.92138974415 176130.03035476385 1.0433532504689413 0.8599907046632048 0.7873520914830431 0.734821247707771 0.9611061112305399 0.8126014653900308 0.9104969459016604 1.0048900394676612 0.9943955669397692 1.0 17.426281385594777 -7.624313801313016 3.6215839135788763 1.0000828352112472 0.8607548717319539 0.34275341722020236 0.08201030164140856 0.2708387545262672 6.844421359936459 0.043905891204394934 0.023632610487660494 2.375123510938863e-08 7.624313801313016 -0.13932796347929333 RSS(ph)AIGIENIQEVQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSSAIGIENIQEVQEK 16 1 J3KPC5;P47736-3;F2Z357;P47736;A0A0A0MQY8;X6R8W7;P47736-2;P47736-4 J3KPC5;P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 RS(0.225)S(0.775)AIGIENIQEVQEK;RS(0.04)S(0.96)AIGIENIQEVQEK 197.05 9.6183e-12 26816000.0 93373.0 95258.0 78494.0 86481.0 93234.0 73108.0 50164.0 72978.0 54912.0 50642.0 True False 109179.20469918672 104714.58470180997 80365.59465015274 81635.74994518509 74965.46698586918 69274.08778072137 45412.102764090814 71062.40482658272 55714.9841167023 59822.99371814855 1.8250374632465933 1.750406962165162 1.3433897178196912 1.3646216090389203 1.2531212887650396 1.1579843046153946 0.7591078269677786 1.187877777588126 0.9313305913642366 1.0 15.868412488506491 -5.131407850255844 0.5054102863494098 0.9614981691907646 2.285315944427193 0.8522381153261802 0.12275275710040161 1.1632300187315068 0.2947599145430183 0.08168169410371573 0.8769993871501194 7.389110304451031e-06 5.131407850255844 1.3238177752364284 RSS(ph)AIGIENIQEVQEK ddPTM_PC-9_Lapatinib_30min_R1 3 RSSAIGIENIQEVQEK 16 1 J3KPC5;P47736-3;F2Z357;P47736;A0A0A0MQY8;X6R8W7;P47736-2;P47736-4 J3KPC5;P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 RS(0.215)S(0.785)AIGIENIQEVQEK;RS(0.116)S(0.884)AIGIENIQEVQEK;RS(0.218)S(0.782)AIGIENIQEVQEK 146.1 1.365e-05 64320700.0 152685.4 169099.0 181937.7 169840.5 138218.9 132468.5 135155.4 117773.9 158703.4 159041.5 True False 150508.07819692654 168707.46165491192 166979.48460583162 182331.1369412989 130089.1360508129 126803.13105415588 142153.08529154884 123246.10534875991 140828.55187110935 186531.61136552232 0.8068770601139287 0.904444348171728 0.8951806258651952 0.9774811658277466 0.6974106699582074 0.6797943261513776 0.7620857625734518 0.6607250344674832 0.7549849102796068 1.0 17.50906061803093 -6.270422965983442 24.975268502275316 0.7383803585159648 0.8965410422055614 0.30810678892163657 0.0975084300243625 653.4064660267057 1816531.659310152 0.028407153920581258 0.032675244629376744 5.365090275654548e-07 6.270422965983442 0.15816068368959657 RSS(ph)AIGIENIQEVQEKR ddPTM_PC-9_Lapatinib_30min_R1 1 RSSAIGIENIQEVQEKR 17 2 J3KPC5;P47736-3;F2Z357;P47736;A0A0A0MQY8;X6R8W7;P47736-2;P47736-4 J3KPC5;P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 RS(0.086)S(0.914)AIGIENIQEVQEKR 47.622 0.031874 3659900.0 35892.0 10561.0 17027.0 15902.0 9680.5 10872.0 6330.6 8058.7 12719.0 10187.0 True False 35380.17349821331 10536.546653365902 15627.105786120714 17071.486127516924 9111.11202259527 10407.029903869836 6658.367492136303 8433.136621730735 11286.452282992308 11947.809376675736 2.9612268142879605 0.8818810479128608 1.3079473645292352 1.4288381735352695 0.7625759447068007 0.8710408390165835 0.557287723817776 0.7058311993321327 0.9446461629213373 1.0 13.544458504774932 -3.2307714762485595 1.5337277324205683 0.9056395837160885 199.99999999583386 0.8279161882245483 0.27188571311215987 57.29377497512184 1.7897713576792793 0.08209805183830708 38861.47795263542 0.0005877985680616689 3.2307714762485595 199.09436041211777 up RSS(ph)DGS(ph)LSHEEDLAK ddPTM_PC-9_AZD4547_30min_R2 1 RSSDGSLSHEEDLAK 15 1 A0A2R8Y7R9;Q13136-2;Q13136;E9PJZ7;H0YEF9 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 2 RS(0.276)S(0.812)DGS(0.888)LS(0.024)HEEDLAK 78.917 0.008606200000000001 5077100.0 46102.0 53761.0 67362.0 85543.0 79325.0 66628.0 62448.0 77331.0 61376.0 67161.0 True False 60761.47701882947 71138.19189634512 66468.73586645104 65822.38297617529 68312.09299916936 62461.74062724742 68005.75102219409 65381.27083959759 64620.21005841262 64809.71383221745 0.9375365732385695 1.0976470607556013 1.0255983545696337 1.015625267943313 1.0540409602180782 0.9637712764625288 1.049314169142155 1.0088190021770473 0.9970759973683045 1.0 15.983922443389021 -6.718339355377514 24.999252758670035 1.0071916811610324 1.0294563647537374 0.059836039034462774 0.04210243502965622 430.2408934632028 249550.63763713714 0.01319692574244655 0.013196857401087832 1.9127607199628266e-07 6.718339355377514 0.022264683592704948 RSS(ph)DGS(ph)LSHEEDLAK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSDGSLSHEEDLAK 15 1 A0A2R8Y7R9;Q13136-2;Q13136;E9PJZ7;H0YEF9 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 2 RS(0.247)S(0.755)DGS(0.944)LS(0.053)HEEDLAK 59.792 0.040311 8961100.0 56524.0 52858.0 56443.0 46770.0 55297.0 58871.0 50762.0 54139.0 59893.0 43384.0 True False 55717.9573947679 52735.61054858583 51802.47441628069 50209.6218201463 52044.53917808491 56353.22456500378 53390.20797962642 56654.49558413648 53147.2196387498 50882.8665944537 1.095023946642999 1.0364119413495088 1.0180730348617433 0.9867687333798764 1.022830328976745 1.1075088401396465 1.0492767320905232 1.1134297136928974 1.0445012868937482 1.0 15.634892329753201 -6.723137925970396 24.99939149884366 1.0691785714558286 1.028809839878285 0.12283841011509511 0.039469852542124165 270.4533124641853 176524.57285105542 0.012867978062643533 0.012867754566871314 1.8917427316900487e-07 6.723137925970396 -0.040368731577543615 RSS(ph)DGSLSHEEDLAK ddPTM_PC-9_AZD4547_30min_R2 1 RSSDGSLSHEEDLAK 15 1 A0A2R8Y7R9;Q13136-2;Q13136;E9PJZ7;H0YEF9 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 RS(0.282)S(0.684)DGS(0.024)LS(0.01)HEEDLAK 61.641000000000005 0.021183 17377000.0 19748.0 18529.0 35999.0 57261.0 55021.0 37506.0 32785.0 41777.0 32821.0 43119.0 True False 26027.453216082693 24518.13689565632 35521.62973867126 44060.36112363111 47382.28388159219 35160.74389093983 35702.801487039316 35321.32458995578 34555.85105460051 41609.41693440214 0.6255183353594057 0.5892449042078509 0.8536920811620993 1.058903593700746 1.138739433823143 0.8450189039267544 0.8580461856344997 0.8488781432732011 0.8304815015571672 1.0 15.344622451836466 -5.353986869814641 3.9596227924928056 0.9356784725412866 0.6057996230194301 0.641494974222711 0.09768592665011351 0.15147448442768108 4.271276845314008 0.029306724024013794 0.06723957675306187 4.426017535025147e-06 5.353986869814641 -0.3298788495218564 RSS(ph)DGSLSHEEDLAK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSDGSLSHEEDLAK 15 1 A0A2R8Y7R9;Q13136-2;Q13136;E9PJZ7;H0YEF9 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 RS(0.155)S(0.823)DGS(0.019)LS(0.002)HEEDLAK 87.49 0.0023591999999999997 12916000.0 41296.0 31645.0 50973.0 37700.0 46814.0 42932.0 29972.0 42592.0 46297.0 34579.0 True False 40707.111467241084 31571.72794676299 46782.1967014701 40472.58376351327 44060.49255986521 41095.89843938006 31523.80350587771 44570.97980974046 41082.54433097687 40555.93407637872 1.0037276269011004 0.7784736972721221 1.1535228510176958 0.997944805987985 1.0864129642997837 1.0133140655072677 0.777292009758896 1.0990002036644064 1.012984789195248 1.0 15.307625402160015 -5.253753260807994 24.9951274949733 1.0141206833376135 0.8911006852813163 0.1830327856586138 0.10666966338436112 1007.571147497851 3276585.135914073 0.02704513992046368 0.06873890233852298 5.575023972622595e-06 5.253753260807994 -0.12301999805629726 RSS(ph)DPALIGLSTSVSDSNFSSEEPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSDPALIGLSTSVSDSNFSSEEPSR 26 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 RS(0.271)S(0.729)DPALIGLSTSVSDSNFSSEEPSR 119.2 3.1055e-12 46186000.0 12453.0 13116.0 15713.0 17530.0 14603.0 12877.0 15156.0 12715.0 14888.0 13436.0 True False 14561.046942038625 14418.069799375777 16087.657511884348 16547.850933026813 11741.646978512628 12201.707451337066 13720.313960062216 12381.244722656103 15105.708834671179 15871.840440682512 0.9174138938995331 0.908405666832408 1.0135974824097058 1.0425918150368725 0.7397785419022094 0.7687644981650518 0.8644437934805891 0.7800761839137851 0.9517301343297534 1.0 13.954181807073295 -6.25531637922814 24.999838059386146 0.8363831963169969 0.9691449783662776 0.3161476008985298 0.08466040646805507 558.9311757758453 2282080.97883236 0.025145397416118962 0.031639613870297 5.554994339982955e-07 6.25531637922814 0.13276178204928069 RSS(ph)DPALIGLSTSVSDSNFSSEEPSRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSDPALIGLSTSVSDSNFSSEEPSRK 27 2 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 RS(0.406)S(0.594)DPALIGLSTSVSDSNFSSEEPSRK 117.01 1.9872e-12 6251100.0 16101.0 15470.0 18713.0 21092.0 30504.0 20375.0 22963.0 23398.0 17144.0 15402.0 True False 18826.58129075435 17005.759362331733 19159.18888944771 19910.283621186623 24526.960174796204 19306.499131862434 20787.77840227688 22783.827292230246 17394.698566738505 18194.260677835075 1.0347538503551064 0.9346771305221971 1.0530347579766264 1.0943167174383772 1.34806028170608 1.0611312805571886 1.1425459253533354 1.2522535372919192 0.9560541576679383 1.0 14.151195808135371 -5.666586567133814 2.9110299077950517 1.141593307438406 0.9869920552555979 0.1870303762680935 0.11082060083563636 0.3526252718629246 5.983640378579307 0.03063921963767543 0.05819600152998431 2.1548320819730417e-06 5.666586567133814 -0.15460125218280807 RSS(ph)DPLGDTASNLGSAVDELMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSDPLGDTASNLGSAVDELMR 22 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 RS(0.157)S(0.843)DPLGDTASNLGSAVDELMR 122.65 2.2916999999999998e-07 10320000.0 8228.8 8690.8 11348.0 9299.4 13207.0 9410.8 11624.0 11087.0 9503.7 8147.4 True False 9621.773313791651 9553.565188503728 11618.57935752966 8778.384767061587 10619.183157242778 8917.281081233428 10522.890569527788 10795.977997647527 9642.673633266028 9624.45912521709 0.9997209389753237 0.9926339822538585 1.2071929660013585 0.912091230567056 1.1033537593213323 0.9265228274354886 1.0933487723956055 1.1217230866886778 1.0018925227705746 1.0 13.232489751144755 RSS(ph)DSWEVWGSASTNR ddPTM_PC-9_AZD4547_30min_R2 3 RSSDSWEVWGSASTNR 16 1 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHH7 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 RS(0.021)S(0.972)DS(0.007)WEVWGSASTNR;RS(0.07)S(0.86)DS(0.07)WEVWGSASTNR;RS(0.233)S(0.747)DS(0.02)WEVWGSASTNR 139.81 2.4374e-05 5314200.0 38657.2 37225.9 39613.0 64213.0 57511.0 42683.5 38358.399999999994 54714.0 38220.299999999996 46683.0 True False 50949.38548028924 49258.4441828492 39087.70573732558 49409.6849309604 49526.59036212082 40014.49399746522 41772.22328993287 46259.208502641195 40240.54702971108 45048.64237919931 1.1309860361921702 1.0934501370366205 0.867677773911648 1.0968074135298416 1.0994025068553266 0.888250830305631 0.9272693045511337 1.0268724218868104 0.8932688068817739 1.0 15.459196008067515 -6.757675734056074 24.99901476280134 0.9475703633839517 1.05127260657852 0.3280321665729605 0.0788336539925083 132.33708223341208 879015.0457818517 0.02735277189740082 0.02635858559751108 1.7471261576633624e-07 6.757675734056074 0.10370224319456833 RSS(ph)DSWEVWGSASTNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSDSWEVWGSASTNR 16 1 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHH7 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 RS(0.144)S(0.846)DS(0.01)WEVWGSASTNR 66.045 0.012562 6576800.0 15255.0 10480.0 17790.0 12897.0 17297.0 17319.0 13450.0 18097.0 12909.0 9940.2 True False 17837.370200015994 11520.385140092863 18214.181068950696 12174.422902638156 13907.777017553433 16410.761151642964 12175.918630432614 17621.972925356466 13097.769703571355 11742.279573420095 1.5190721774665277 0.9811029509270488 1.55116227262894 1.036802336932623 1.184418828609325 1.3975788132987803 1.0369297166109133 1.5007284416260778 1.1154367107064591 1.0 13.51942489106565 -8.518426213480936 24.184596582831578 0.9999999592300529 1.2633608382617847 0.16563786650632972 0.20275032966735573 349.3818255954365 1897713.479877033 0.1773718376627682 0.045797211600746866 3.0309152057477284e-09 8.518426213480936 0.2633608790317318 RSS(ph)DSWEVWGSASTNR ddPTM_PC-9_Lapatinib_30min_R1 1 RSSDSWEVWGSASTNR 16 1 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHH7 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 RS(0.045)S(0.91)DS(0.045)WEVWGSASTNR 122.16 9.2464e-05 3803100.0 20769.0 16324.0 19914.0 20178.0 16882.0 13668.0 13991.0 13863.0 17032.0 14836.0 True False 20472.83025143187 16286.202780943573 18276.747790263 21661.95743183478 15889.03395128902 13083.451501664174 14715.385521511236 14507.125589369656 15113.67680508885 17400.38283227263 1.176573552937051 0.9359680725378882 1.0503646940666713 1.244912691901133 0.9131427799289279 0.7519059567699966 0.8456932047620523 0.8337245064782812 0.8685830047978825 1.0 14.086831427241004 -6.478479335102394 9.433813785306697 0.8468692352070459 1.0857686849878267 0.5914885596861312 0.09506929332895357 0.3469742920253608 71.77947668471029 0.029176614923392404 0.03286959991843806 3.322925962088995e-07 6.478479335102394 0.23889944978078081 RSS(ph)DSYPLAPVR ddPTM_PC-9_AZD4547_30min_R2 5 RSSDSYPLAPVR 12 1 Q52LW3 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 RS(0.132)S(0.866)DS(0.002)YPLAPVR;RS(0.074)S(0.887)DS(0.039)YPLAPVR;RS(0.052)S(0.936)DS(0.011)YPLAPVR;RS(0.177)S(0.732)DS(0.091)YPLAPVR;RS(0.04)S(0.958)DS(0.002)YPLAPVR 174.94 0.00010824 93454200.0 261082.0 255810.0 295814.0 431537.0 374235.0 268235.0 274795.0 385259.0 282857.0 323506.0 True False 344100.64515704336 338495.579862801 291891.31307856576 332052.8118301884 322278.93001631444 251462.22304661234 299251.2226515475 325726.07392109913 297808.24355598947 312180.1534075635 1.1022502276363686 1.0842956420130965 0.9350091922643465 1.0636576611476012 1.0323491948431667 0.8055035539633376 0.9585850329853072 1.0433913570919766 0.9539627689502383 1.0 18.252019296536062 -5.197914786748756 6.760732987314298 0.9743893505179199 1.0953135720704963 0.3233425987888109 0.06901230191599768 0.31046755560201417 27.395298711744964 0.01851590757753257 0.0498034866104823 6.339940955183733e-06 5.197914786748756 0.12092422155257643 RSS(ph)DSYPLAPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RSSDSYPLAPVR 12 1 Q52LW3 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 RS(0.011)S(0.981)DS(0.007)Y(0.001)PLAPVR;RS(0.013)S(0.95)DS(0.036)YPLAPVR;RS(0.21)S(0.788)DS(0.002)YPLAPVR 136.83 9.485e-05 33726400.0 182316.0 178132.0 132483.0 162672.0 179662.0 155279.0 129685.0 177615.0 131041.0 98608.2 True False 213178.4978948616 195815.76772662447 135641.89716457552 153558.0152297397 144458.52081445843 147135.8958869431 117400.29796190755 172952.79444864808 132957.22671978408 116485.08607791836 1.8300926330797729 1.6810372410734264 1.1644571999014786 1.3182633107814574 1.240146062284989 1.2631307649849872 1.0078569018129668 1.4847634171206927 1.141409867962387 1.0 16.829785728726137 -5.168510869387294 3.8263871136657164 1.219804367681517 1.7995832908987455 0.7231051345223526 0.13749549628565333 0.11429251002394178 3.03363082877858 0.03379244354483365 0.10358657228639341 6.784051413727887e-06 5.168510869387294 0.5797789232172286 RSS(ph)DSYPLAPVR ddPTM_PC-9_Lapatinib_30min_R1 3 RSSDSYPLAPVR 12 1 Q52LW3 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 RS(0.048)S(0.668)DS(0.284)YPLAPVR;RS(0.191)S(0.756)DS(0.052)Y(0.001)PLAPVR;RS(0.149)S(0.698)DS(0.153)YPLAPVR 141.65 0.00011614 47302200.0 169055.0 170874.0 163383.0 144896.0 124527.0 107173.0 101336.0 114026.0 145954.0 132949.0 True False 166644.2446991095 170478.35175146718 149950.28041661865 155552.13519888645 117202.56668950173 102589.46062246527 106582.68223914396 119324.06423237875 129515.12355624339 155929.05750659318 1.0687183477143973 1.0933071390126168 0.9616570690185713 0.9975827320851293 0.7516403200509696 0.6579239447921851 0.6835331652962586 0.7652458505197682 0.8306028756107057 1.0 17.250530274918965 -6.200848381150504 3.7047793133578653 0.7575959003548726 1.0376047559294146 0.6192004181236873 0.09479900127497859 0.14736917909145988 4.074012283142593 0.02913044496519833 0.03766678603004961 6.297259914657984e-07 6.200848381150504 0.280008855574542 RSS(ph)DTEEESR ddPTM_PC-9_AZD4547_30min_R2 1 RSSDTEEESR 10 1 C9J8Q2;C9JVB3;F8WDM0;C9J367;C9J713;Q96IZ7-2;Q96IZ7 C9J8Q2 RSRC1 Serine/Arginine-related protein 53 1 RS(0.441)S(0.517)DT(0.042)EEESR 64.798 0.02314 1267500.0 0.0 0.0 625.94 0.0 0.0 418.3 0.0 0.0 0.0 467.93 True False 0.0 0.0 617.6396266180695 0.0 0.0 392.14363487389045 0.0 0.0 0.0 451.54791312680726 0.0 0.0 1.3678274412589724 0.0 0.0 0.8684430233736139 0.0 0.0 0.0 1.0 8.818735267985799 -10.727406326071103 4.802361931179586 1.000108276461686 0.26309064289689277 0.1964422113934431 0.45512764175381387 0.00054761248983261 9.070750538851586e-05 0.4441573949910759 0.10770786279386961 1.873241082922016e-11 10.727406326071103 -0.7370176335647932 RSS(ph)DTEEESR ddPTM_PC-9_Lapatinib_30min_R1 1 RSSDTEEESR 10 1 C9J8Q2;C9JVB3;F8WDM0;C9J367;C9J713;Q96IZ7-2;Q96IZ7 C9J8Q2 RSRC1 Serine/Arginine-related protein 53 1 RS(0.12)S(0.43)DT(0.43)EEES(0.019)R 87.21600000000001 0.01054 0.0 695.91 1052.0 531.18 867.57 2128.6 1034.7 3479.0 2170.7 2551.7 1182.9 True False 685.9861957857358 1049.5641586346871 487.5084308140957 931.3739919286796 2003.3999329886158 990.448293003507 3659.1255971222645 2271.55864652995 2264.3006754077724 1387.3626888848264 0.4944533980059225 0.7565175040697797 0.3513922024283059 0.6713269712315283 1.4440347495570645 0.7139072579497129 2.6374686492855735 1.6373214190701981 1.6320899311684935 1.0 10.438129275679604 -6.580616995286687 1.3375639761702538 1.7144972425617533 0.5467309214159582 0.4843130223652895 0.4779881944803728 0.341176089719752 1.2702087470049264 0.2052698794198478 0.21785193468393674 2.6265338649856866e-07 6.580616995286687 -1.1677663211457951 RSS(ph)FSEGQTLTVTSGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSSFSEGQTLTVTSGAK 17 1 E9PEM3;H7C357;H0Y6E6;Q92622-3;Q92622-2;Q92622;H7C3H3 E9PEM3 KIAA0226 Run domain Beclin-1 interacting and cysteine-rich containing protein 1 RS(0.097)S(0.899)FS(0.004)EGQTLTVTSGAK;RS(0.011)S(0.941)FS(0.048)EGQTLTVTSGAK 138.97 3.5734e-08 0.0 34891.0 39223.0 33088.0 43409.0 49245.0 43482.0 44534.0 43662.0 36399.0 37725.0 True False 40797.35717133784 43116.80022422354 33876.94340693877 40976.934463876816 39595.795758190376 41201.727374313734 40315.41712176105 42515.91876371299 36931.26651485738 44564.24386906431 0.9154728910290931 0.9675200672293789 0.7601821654704554 0.9195025183030708 0.8885104361812601 0.9245467620940658 0.904658390260432 0.9540365789360283 0.8287196933794359 1.0 15.443599007140206 -6.753775439804279 22.2433357371777 0.9184112041377295 0.8889315862997468 0.05795453705754705 0.06370950886443262 163.88452281400782 475643.10334521695 0.020837813345742643 0.02039553267306571 1.76288734511382e-07 6.753775439804279 -0.029479617837982697 RSS(ph)GENVENNSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSGENVENNSQR 13 1 Q9NVW2-2;Q9NVW2 Q9NVW2-2 RLIM E3 ubiquitin-protein ligase RLIM 1 RS(0.364)S(0.636)GENVENNSQR 119.0 0.00034476 1218100.0 4866.6 6205.7 4094.9 5748.3 5184.4 6322.0 5669.9 5889.1 6190.8 5717.8 True False 5690.419260268625 6821.760883957472 4192.537945994731 5426.241387240045 4168.554036526796 5990.463190755057 5132.8060254788 5734.51736501723 6281.328738157067 6754.3918779201 0.8424769191835657 1.0099741038505035 0.6207128667941237 0.803364904689386 0.6171620053840333 0.8868989687047472 0.7599212657852715 0.849005723781469 0.929962141919917 1.0 12.721610169060932 -8.303364332871134 1.7100697126918833 0.9981143488984092 0.7898526805169478 0.2883893367262911 0.10989784360705127 0.46082244475441037 2.6035624770467156 0.10425824695064743 0.030867198373963466 4.973197047323736e-09 8.303364332871134 -0.20826166838146143 RSS(ph)GENVENNSQR ddPTM_PC-9_Lapatinib_30min_R1 1 RSSGENVENNSQR 13 1 Q9NVW2-2;Q9NVW2 Q9NVW2-2 RLIM E3 ubiquitin-protein ligase RLIM 1 RS(0.041)S(0.959)GENVENNSQR 82.925 0.018234 0.0 0.0 679.34 4750.1 625.06 2261.3 3241.5 1182.4 810.07 2572.3 571.19 True False 0.0 677.7670299685252 4359.565113916253 671.0289975390348 2128.2947798868527 3102.8686013055653 1243.6188864723674 847.7088095059277 2282.5804864801585 669.9194304371659 0.0 1.0117142437953146 6.507596161334436 1.0016562694728004 3.176941409951346 4.631704142811237 1.8563708260571354 1.2653891960601031 3.407246278840765 1.0 9.387843786392516 -5.0160343963925245 24.688768222166985 2.899736188394052 0.2529265398044683 0.252859231115666 1.6548762484254107 687.143616414438 1058032.9715143798 0.40732209694377597 1.1535681611614894 9.637526907899144e-06 5.0160343963925245 -2.6468096485895836 RSS(ph)GFISELPSEEGK ddPTM_PC-9_AZD4547_30min_R2 2 RSSGFISELPSEEGK 15 1 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 RS(0.1)S(0.9)GFISELPSEEGK;RS(0.112)S(0.873)GFIS(0.014)ELPS(0.001)EEGK 90.259 0.0062816 12670300.0 39688.0 40633.0 51297.0 75640.0 64692.0 68471.0 49597.0 62743.0 48754.0 62624.0 True False 52307.95843831731 53766.82262837733 50616.76826313559 58202.36662635049 55710.632465203504 64189.49754590043 54011.03691787984 53047.51104070649 51331.03690673634 60431.55282126209 0.8655736282836903 0.8897143978312625 0.8375884103598065 0.9631122138875887 0.9218798767256301 1.0621851425157514 0.8937555696711591 0.8778114836400892 0.8494078756929799 1.0 15.883014392888569 -5.762431956125462 24.99957187767657 0.9358370244781232 0.8668343684730597 0.24633485095352325 0.05916730687324683 42.65959844775732 1074502.4300447416 0.017321521144246992 0.027443745260958736 1.7280967119808837e-06 5.762431956125462 -0.0690026560050635 RSS(ph)GFISELPSEEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSGFISELPSEEGK 15 1 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 RS(0.26)S(0.74)GFISELPSEEGK 71.286 0.032300999999999996 9224500.0 31910.0 40017.0 45613.0 40898.0 49517.0 56442.0 53291.0 48635.0 44531.0 42250.0 True False 37311.732748771574 43989.62329686032 46700.58690826582 38606.61765310498 39814.49931075871 53482.08215953764 48242.89068657136 47358.38278304202 45182.18163062485 49909.590549183995 0.747586432551521 0.881386178744749 0.9357036672589845 0.7735310433985555 0.7977324372461649 1.071579261040683 0.9666056193955315 0.9488834162318391 0.9052805509614337 1.0 15.607029447783068 -6.745225598629299 24.99995457953076 0.9745334888931513 0.8332466568507709 0.5840438361239644 0.06368905097097184 196.50642987588958 302991.84978955716 0.02195874278865121 0.021894595827148266 1.797936716230286e-07 6.745225598629299 -0.14128683204238035 RSS(ph)GFISELPSEEGK ddPTM_PC-9_Lapatinib_30min_R1 2 RSSGFISELPSEEGK 15 1 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 RS(0.325)S(0.674)GFISELPSEEGK;RS(0.252)S(0.745)GFIS(0.004)ELPSEEGK 138.46 7.586e-05 83799000.0 307765.0 283176.0 285622.0 261374.0 289912.0 310574.0 256737.0 273740.0 298552.0 199711.0 True False 303376.2146628115 282520.32337028167 262139.26169280335 280596.3158781045 272859.94614892226 297291.47400335496 270029.58563621115 286458.9597370017 264925.92986806494 234230.78025182014 1.2952021691455473 1.2061622433505355 1.1191495046508362 1.1979480902400488 1.1649192555119021 1.2692246240384746 1.1528356151394958 1.222977438870465 1.1310466096012002 1.0 17.837571147196527 -8.610950940896503 3.079352826175598 1.0000832500071966 1.1996438524872373 0.6125460728337779 0.04955737994600535 0.2500051624815327 5.621464612610979 0.047180591221180436 0.012539117756163594 2.449339910415238e-09 8.610950940896503 0.1995606024800407 RSS(ph)GREEDDEELLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSGREEDDEELLR 14 2 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 RS(0.26)S(0.74)GREEDDEELLR 58.626000000000005 0.020028 6247700.0 11719.0 16189.0 18093.0 16874.0 11851.0 14553.0 14979.0 16250.0 15802.0 14010.0 True False 13702.795239199455 17796.136930626282 18524.405738084613 15928.604486246126 9528.881623115323 13789.815060907684 13560.08068143124 15823.454718298202 16033.074355553072 16549.902096901027 0.8279683564874566 1.075301643866438 1.119306061729109 0.962459136796269 0.5757666460697437 0.833226382861191 0.8193450693566561 0.9561056389125799 0.9687715529480545 1.0 14.014535062156979 -6.012688647623605 24.96620491558386 0.8457522163744676 1.0187329429230625 0.2064628932682323 0.1321198522072694 844.7969026497465 1662228.2848954282 0.03962819902977126 0.05386243159483013 9.712059901941228e-07 6.012688647623605 0.17298072654859487 RSS(ph)ITEPEGPGGPNIQK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSITEPEGPGGPNIQK 17 1 H0YJL1;A0A3B3ISJ2;Q96KQ4 H0YJL1 PPP1R13B Apoptosis-stimulating of p53 protein 1 1 RS(0.119)S(0.781)IT(0.099)EPEGPGGPNIQK 144.18 5.1341e-05 12343000.0 92369.0 48159.0 72574.0 67936.0 57373.0 67016.0 60583.0 50058.0 66319.0 50953.0 True False 91051.80112160005 48047.49079438016 66607.24586374135 72932.24006785228 53998.4329396579 64149.881901926114 63719.69130510433 52383.87742571347 58849.45584996982 59760.158159395185 1.5236204843826262 0.8040054155517053 1.1145761309078748 1.2204157805828406 0.9035858438598952 1.0734556915131055 1.066257072733109 0.8765685874858741 0.984760711191622 1.0 15.866896345873942 -4.74643986883046 24.995499802213363 1.0120542243665207 1.5236218477727543 0.6417876086087966 0.11615927020771483 537.0531390210393 894906.874472402 0.02899437011247527 0.6591922508462071 1.79291677730045e-05 4.74643986883046 0.5115676234062336 RSS(ph)ITEPEGPNGPNIQK ddPTM_PC-9_AZD4547_30min_R2 3 RSSITEPEGPNGPNIQK 17 1 Q13625-2;Q13625;Q13625-3 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 RS(0.149)S(0.467)IT(0.384)EPEGPNGPNIQK;RS(0.079)S(0.92)IT(0.001)EPEGPNGPNIQK;RS(0.225)S(0.769)IT(0.006)EPEGPNGPNIQK 110.32 0.00058789 68779000.0 62922.0 49379.8 84754.0 116221.0 107748.0 89666.0 67397.0 113244.0 78482.0 97144.0 True False 82929.88714109556 65340.8546753807 83630.1065827201 89428.04404655052 92789.05006586219 84059.17084533173 73395.20243471078 95744.74188823876 82630.39829582145 93743.01812833219 0.8846513457414644 0.6970210259918287 0.8921209094018315 0.953970181801971 0.9898235827956378 0.8966979357359341 0.7829404674621668 1.021353310357111 0.8814565601323204 1.0 16.51642362378694 -5.4676453024270115 8.215197346603272 0.9275701452626686 0.7910886859639609 0.3401763449453865 0.07760014113898453 0.3674480564494034 50.52577483067797 0.019876591925468482 0.04123771741119804 3.406863218980214e-06 5.4676453024270115 -0.1364814592987077 RSS(ph)ITEPEGPNGPNIQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSSITEPEGPNGPNIQK 17 1 Q13625-2;Q13625;Q13625-3 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 RS(0.032)S(0.967)IT(0.001)EPEGPNGPNIQK;RS(0.222)S(0.708)IT(0.07)EPEGPNGPNIQK 120.99 7.383e-05 66321000.0 39791.0 29860.0 40384.0 47632.0 52368.0 47057.0 46916.0 45097.0 49034.0 42837.0 True False 46526.83039192638 32824.30346213482 41346.90771717288 44963.333465027565 42106.86632683344 44589.24808088591 42471.77683757446 43913.25153422118 49751.02948678577 50603.00900249459 0.919447900610668 0.6486630757573462 0.8170839744951647 0.8885505892112264 0.832102026279854 0.8811580370386232 0.8393132676256608 0.8677992158935919 0.9831634613730812 1.0 15.62693555387433 -7.9312295746298185 0.3604293998582211 1.0168218552045574 0.7818842317800515 0.4253530527115259 0.07060130767067595 1.1678772661593977 0.4692620961039129 0.09926491034177888 0.08460961501009463 1.1715758891006316e-08 7.9312295746298185 -0.23493762342450586 RSS(ph)LLNAK ddPTM_PC-9_AZD4547_30min_R2 3 RSSLLNAK 8 1 E9PCH4;Q8TEU7;A0A5F9ZHG7;Q8TEU7-4;B7Z7Y1;Q8TEU7-2;Q8TEU7-5;Q8TEU7-3;D6RE77 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 1 RS(0.002)S(0.998)LLNAK;RS(0.006)S(0.994)LLNAK;RS(0.004)S(0.996)LLNAK 84.507 0.020454 38077800.0 169156.0 166627.0 252532.0 301210.0 246806.0 206498.0 193868.0 266190.0 179081.0 220716.0 True False 222944.0893366252 220485.91918141965 249183.26067852258 231770.68814810985 212541.24708166384 193585.64741618172 211121.8764279194 225056.4519376766 188546.8560588926 212988.80002072194 1.046740905225696 1.0351995934057017 1.1699359809261296 1.0881825153508569 0.9978987020021026 0.908900596638638 0.9912346396025477 1.0566586220297995 0.885243055224259 1.0 17.700418043012846 -6.328837490402684 4.3245832951774315 0.971933275874651 1.0877707883808447 0.49350388642083864 0.05585620407330395 0.19805731535116125 7.312585115788233 0.017980994697137 0.02082785357892284 4.6898884127065333e-07 6.328837490402684 0.11583751250619378 RSS(ph)LLNAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSSLLNAK 8 1 E9PCH4;Q8TEU7;A0A5F9ZHG7;Q8TEU7-4;B7Z7Y1;Q8TEU7-2;Q8TEU7-5;Q8TEU7-3;D6RE77 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 1 RS(0.064)S(0.936)LLNAK;RS(0.001)S(0.999)LLNAK 111.52 0.0055008 27558000.0 88590.0 84556.0 90932.0 110259.0 125862.0 103104.0 109510.0 104031.0 111562.0 89321.0 True False 103586.53726774277 92950.16086886401 93100.16374153024 104081.54569450098 101200.24460792709 97697.04473578146 99136.4200162586 101300.29647995574 113193.38319543158 105514.19023535302 0.9817308651726318 0.8809256902937462 0.8823473272539659 0.986422257161274 0.9591150193371761 0.9259137990621437 0.9395553318006936 0.9600632507722606 1.072778769783949 1.0 16.687077509440314 -8.098454092078862 4.687016760803192 1.0350238156609148 0.935512440675653 0.5252753695297447 0.037320999499868744 0.1785941895895609 6.286393675276444 0.027439833166534925 0.009868447546843831 7.971607515244875e-09 8.098454092078862 -0.09951137498526186 RSS(ph)LLNAK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSLLNAK 8 1 E9PCH4;Q8TEU7;A0A5F9ZHG7;Q8TEU7-4;B7Z7Y1;Q8TEU7-2;Q8TEU7-5;Q8TEU7-3;D6RE77 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 1 RS(0.001)S(0.999)LLNAK 110.54 0.005524 8870600.0 85187.0 74401.0 79410.0 63520.0 71231.0 71439.0 71554.0 65444.0 86198.0 58643.0 True False 83972.21775861729 74228.72905568389 72881.21633146451 68191.47269650834 67041.33262553423 68383.72050244277 75258.71600358911 68484.76715506802 76489.47353481963 68779.3644131143 1.2208926103801876 1.0792296452441563 1.0596378281967391 0.9914524985564731 0.9747303307843788 0.9942476364234025 1.094204877375101 0.9957167784180614 1.1120991621178056 1.0 16.06968816359844 -4.581293929710204 1.5130817855190009 1.0242715591959215 1.3807356325825613 0.6394259969339133 0.04394618654174366 1.1845797375776692 1.752701637987484 0.012489156031745129 0.7297803454274812 2.6224430779625934e-05 4.581293929710204 0.35646407338663977 RSS(ph)LLSLMTGK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSLLSLMTGK 11 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 RS(0.014)S(0.985)LLSLMTGK 93.823 0.010124 8738500.0 41943.0 52740.0 51123.0 53653.0 38652.0 34393.0 33634.0 32035.0 44713.0 41625.0 True False 41344.885128595844 52617.88377033593 46919.86428048686 57598.82060116122 36378.56535275577 32922.091563998845 35375.403947574065 33523.46304951719 39676.95109123633 48819.82578817386 0.8468871910356397 1.077797450540721 0.9610821735429615 1.1798243781343847 0.7451596716178397 0.6743590545948631 0.7246114334996955 0.6866772363132424 0.8127220949823155 1.0 15.575179526471342 -6.2858231220925544 24.21890157642177 0.7508117635018221 1.0168323647102957 0.4982391009004954 0.11784605377054393 378.0208638977782 375464.0626621017 0.034621215805438456 0.03927823401151851 5.178176839493728e-07 6.2858231220925544 0.2660206012084736 RSS(ph)LNSISSSDAK ddPTM_PC-9_AZD4547_30min_R2 1 RSSLNSISSSDAK 13 1 Q14123-2;Q14123;A0A0A0MS69;Q14123-3 Q14123-2 PDE1C Calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase 1C 1 RS(0.008)S(0.992)LNSISSSDAK 116.87 0.0003927 5747500.0 17385.0 16025.0 21189.0 26172.0 21024.0 18853.0 20723.0 20870.0 22010.0 18531.0 True False 22913.06836953603 21204.76786404513 20908.020015353348 20138.449753369187 18105.180500656013 17674.118929661636 22567.306854229566 17645.02104489018 23173.403665694434 17882.235330397416 1.2813313294556006 1.185800738680575 1.1692061774744962 1.1261707153096518 1.0124674105971316 0.9883618352576979 1.2619958543923282 0.9867346402099965 1.2958896490028144 1.0 14.126239468336331 -5.093777996681116 1.228180212802682 1.0950032374745917 1.3004006550783502 0.23653364798715804 0.10478008107376761 1.3385792410342203 2.5228778037682127 0.03161433126450889 0.30424966749345655 8.057902410282754e-06 5.093777996681116 0.20539741760375851 RSS(ph)LNSISSSDAK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSLNSISSSDAK 13 1 Q14123-2;Q14123;A0A0A0MS69;Q14123-3 Q14123-2 PDE1C Calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase 1C 1 RS(0.033)S(0.961)LNS(0.006)IS(0.001)SSDAK 107.63 0.00074514 0.0 16699.0 21860.0 24598.0 21277.0 25612.0 20658.0 18288.0 17108.0 19538.0 18313.0 True False 16460.869197778462 21809.3845130744 22575.647391025854 22841.781557991308 24105.552515129395 19774.505496150043 19234.86315612875 17902.900135824573 17337.424695738955 21478.377649461334 0.7663925770572011 1.015411166942647 1.051087179836045 1.0634779744905065 1.12231719306481 0.9206703513124036 0.895545439699965 0.8335313042730473 0.8072036435290898 1.0 14.390597404275454 -6.9875238279180145 24.384634883449397 0.8756134295700302 1.0114511402260706 0.24459860575949965 0.0994779262010859 223.82219356272773 437456.9990234859 0.036019388090680525 0.03174344168161003 1.0291440608241192e-07 6.9875238279180145 0.13583771065604044 RSS(ph)LPNGEGLQLK ddPTM_PC-9_AZD4547_30min_R2 2 RSSLPNGEGLQLK 13 1 Q9ULR3 Q9ULR3 PPM1H Protein phosphatase 1H 1 RSS(1)LPNGEGLQLK;RS(0.249)S(0.751)LPNGEGLQLK 167.35 0.00013041 36753000.0 119739.0 106278.0 140002.0 175102.0 159985.0 151356.0 116422.0 154543.0 133197.0 150927.0 True False 157813.5112740798 140630.28512043617 138145.48200431833 134734.9391989322 137773.84429211656 141891.68539319295 126783.3324607012 130661.93039484756 140237.52149293516 145643.09166860324 1.083563315403721 0.9655815700508937 0.9485206639162467 0.9251035367026437 0.9459689623014018 0.9742424701890684 0.8705070114083022 0.8971378518395925 0.9628848157936118 1.0 17.152077745761844 -4.444673682243028 1.5582611070730665 0.9342568514062134 1.28355891179486 0.5879780056199442 0.03547686090007813 1.853034027265328 2.1623770685568093 0.009933383938096106 1.2776059320730737 3.5919172074178575e-05 4.444673682243028 0.34930206038864664 RSS(ph)LPNGEGLQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RSSLPNGEGLQLK 13 1 Q9ULR3 Q9ULR3 PPM1H Protein phosphatase 1H 1 RS(0.306)S(0.694)LPNGEGLQLK;RS(0.024)S(0.976)LPNGEGLQLK;RS(0.065)S(0.935)LPNGEGLQLK;RS(0.235)S(0.765)LPNGEGLQLK 144.25 4.1578999999999996e-05 37739200.0 190095.0 172331.0 200879.0 215358.0 235230.0 218037.0 198817.0 175761.0 180711.0 156948.0 True False 222274.32895260834 189438.88278409798 205668.7171978503 203292.1894600568 189138.3701126844 206602.75588779824 179983.61444956993 171147.45998417327 183353.55650337617 185401.4300003158 1.1988814161370263 1.0217768157655274 1.1093157005180594 1.0964974189234167 1.0201559400721032 1.1143536265467118 0.97077791929255 0.9231183383207009 0.9889543813284711 1.0 17.50029284594291 -7.272308067279119 21.940025455276466 0.9643057766579347 1.0877585716811875 0.5781156976753232 0.05112758116118264 98.7295731779796 199296.97433710695 0.020179321536818638 0.01380373555639913 5.341853000264851e-08 7.272308067279119 0.12345279502325279 RSS(ph)LPNGEGLQLK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSLPNGEGLQLK 13 1 Q9ULR3 Q9ULR3 PPM1H Protein phosphatase 1H 1 RS(0.444)S(0.556)LPNGEGLQLK 77.027 0.0076002 17562000.0 73105.0 69773.0 69901.0 63648.0 64728.0 67336.0 71437.0 66884.0 81335.0 52755.0 True False 72062.50929418506 69611.44490534037 64154.009605663035 68328.88624350379 60920.82630014429 64456.196247882566 75135.65831607446 69991.67481204658 72174.1958044798 61873.631458381125 1.1646723748978176 1.1250583368807765 1.0368554114819621 1.1043296576097161 0.9846007881583978 1.0417393440247416 1.2143405283495272 1.1312036026061603 1.1664774493319867 1.0 15.917037089971819 -7.233529725270619 24.982795688686423 1.138939065053641 1.073755089124977 0.10991604727465842 0.06926435951720915 1321.4827181705878 1182902.3142993897 0.026477677114736455 0.02050332638524699 5.8407722857920676e-08 7.233529725270619 -0.0651839759286641 RSS(ph)LPSFETLDYGDEEDIETQLSSSGK ddPTM_PC-9_AZD4547_30min_R2 1 RSSLPSFETLDYGDEEDIETQLSSSGK 27 1 K7EPU8;K7EQI2;A0A0C4DGP8;K7EJF0;Q96ST8-3;Q96ST8 K7EPU8 CEP89 Centrosomal protein of 89 kDa 1 RS(0.218)S(0.625)LPS(0.088)FET(0.066)LDY(0.003)GDEEDIETQLSSSGK 102.58 4.9343e-10 4006900.0 11199.0 11180.0 14946.0 22109.0 18934.0 17061.0 12246.0 19832.0 11747.0 11622.0 True False 14760.049046329263 14793.716363184065 14747.80627445708 17012.11163064494 16305.340924629993 15994.172972946324 13335.870276354539 16767.420094023106 12367.922438024192 11215.117317461492 1.3160851222972454 1.3190870808057296 1.314993491106449 1.5168910987812636 1.4538716326438443 1.4261262294638712 1.1890977061462495 1.4950730892415096 1.1027902863546357 1.0 13.453157091586176 -8.419603572322828 4.6500693128711035 1.0033298904229637 1.3763496904983445 0.6636109616782471 0.09440179350011264 0.12426891037231555 4.019092077740034 0.09248800167300898 0.024148330461824942 3.805365948566623e-09 8.419603572322828 0.3730198000753808 RSS(ph)LPSFETLDYGDEEDIETQLSSSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSLPSFETLDYGDEEDIETQLSSSGK 27 1 K7EPU8;K7EQI2;A0A0C4DGP8;K7EJF0;Q96ST8-3;Q96ST8 K7EPU8 CEP89 Centrosomal protein of 89 kDa 1 RS(0.19)S(0.65)LPS(0.136)FET(0.022)LDY(0.001)GDEEDIETQLSSSGK 88.541 2.495e-07 2773700.0 13386.0 13809.0 13491.0 16711.0 17982.0 16029.0 15313.0 17308.0 16775.0 13018.0 True False 15651.985414448658 15179.866259498318 13812.676604902412 15774.736847792983 14458.556184867088 15188.411022558194 13862.441783480646 16853.683339341867 17020.302639817917 15378.060349568694 1.0178127188119435 0.9871118928157975 0.8982066847780198 1.0257949630322145 0.9402067527503626 0.9876675391629726 0.9014428002208643 1.0959563791681024 1.106791250191399 1.0 13.908585925727692 -7.7763452624030975 24.999766857617345 1.0760304033579522 0.9659122232422983 0.47750137485063615 0.048710733533909575 191.22907172430985 320719.85247972695 0.025240478974872995 0.012202278059159582 1.6736118321924182e-08 7.7763452624030975 -0.11011818011565389 RSS(ph)LYGIAK ddPTM_PC-9_AZD4547_30min_R2 2 RSSLYGIAK 9 1 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 RS(0.108)S(0.892)LYGIAK;RS(0.205)S(0.795)LYGIAK 86.288 0.0053997 24184000.0 166068.0 145672.0 177936.0 229346.0 296740.0 210417.0 154045.0 289260.0 174572.0 196935.0 True False 218874.16957101625 192757.62522877916 175576.45237868288 176473.82306037776 255542.77310524505 197259.59172665415 167754.70657529304 244561.51353353736 183799.51952419832 190040.36559234915 1.151724629074424 1.0142983288206187 0.9238903105212266 0.928612310917815 1.3446762865811546 1.0379878564840839 0.8827319714546302 1.2868924597742575 0.9671604185316192 1.0 17.53594636170213 -4.748701636425122 23.829652156351905 1.048860662116919 1.15172506411606 0.04644828762886066 0.14567672812489074 1334.4804809406019 2496252.958560199 0.03630896969128625 0.6036185875572465 1.78360369578378e-05 4.748701636425122 0.10286440199914093 RSS(ph)LYGIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSLYGIAK 9 1 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 RS(0.034)S(0.966)LYGIAK 69.846 0.018000000000000002 5488700.0 199440.0 187670.0 176640.0 178290.0 225930.0 157710.0 135240.0 175320.0 130630.0 125270.0 True False 233201.25288044548 206300.63733217787 180851.76751093028 168300.98932397898 181660.63835207565 149439.4099674122 122429.08814718992 170718.0357668945 132540.21662231986 147980.45936322547 1.5758922082275828 1.3941072910566021 1.2221327619143318 1.1373190085244684 1.2275988271274418 1.0098590760595334 0.8273328024119831 1.1536525599495437 0.895660259419747 1.0 17.17504715677081 -3.491164791080579 0.39541376520573246 0.9575559524186764 3.1370378905648098 0.8036958195014933 0.09533513193860611 6.596057013478964 0.3656617752369839 0.07381525403462182 8.391398739795493 0.000322726931658095 3.491164791080579 2.1794819381461332 RSS(ph)LYGIAK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSLYGIAK 9 1 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 RS(0.356)S(0.644)LYGIAK 81.278 0.008006399999999999 9665800.0 84667.0 78500.0 84611.0 84051.0 78135.0 76322.0 71872.0 78759.0 90039.0 89129.0 True False 83459.63305397384 78318.23807302567 77654.61018790508 90232.3909259166 73539.25291932041 73057.8859752717 75593.18048760307 82418.43066386534 79897.85966729654 104534.82889307267 0.798390679333714 0.7492071197929294 0.7428587295755464 0.8631801657054813 0.7034904413967402 0.6988855939105393 0.7231387020772412 0.7884303397881876 0.7643180795658356 1.0 16.67362417367756 -9.38246362809697 1.3128715813489826 1.000356158973269 0.7559081330722955 0.7077666372971589 0.04646102136698259 5.409696314115325 7.65581791777811 0.05087529142719149 0.013745005761945341 4.145112976574821e-10 9.38246362809697 -0.24444802590097348 RSS(ph)MGSTAVATDVK ddPTM_PC-9_AZD4547_30min_R2 1 RSSMGSTAVATDVK 14 1 Q6UXY1;B0QYF0;Q6UXY1-2 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 RS(0.026)S(0.967)MGS(0.007)TAVATDVK 106.35 0.00085022 30466000.0 41515.0 37218.0 46931.0 57615.0 50134.0 50848.0 48451.0 57727.0 47989.0 48399.0 True False 54715.90643435655 49247.99066234206 46308.664275829346 44332.751892876586 43173.75947583184 47668.46652179678 52763.045137976005 48806.61858449329 50525.600568514754 46704.56574150908 1.1715322809591464 1.054457736207415 0.9915232813024986 0.9492166598494989 0.9244012612124726 1.0206382559174727 1.129719210537106 1.045007437915561 1.0818128756009329 1.0 15.51127597125437 -9.705794411778026 14.37718057536828 0.9999995905757894 1.0358791429466425 0.024044597986089045 0.07203024435781476 0.0 0.0 0.07609689987313363 0.018456209174057717 1.9688180768579258e-10 9.705794411778026 0.03587955237085316 RSS(ph)MGSTAVATDVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSSMGSTAVATDVK 14 1 Q6UXY1;B0QYF0;Q6UXY1-2 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 RS(0.194)S(0.767)MGS(0.033)T(0.006)AVATDVK;RS(0.026)S(0.974)MGS(0.001)TAVATDVK 124.04 3.7847e-05 34055500.0 89998.0 95601.0 90879.0 100530.0 105634.0 87927.0 87569.0 101979.0 78358.0 61964.0 True False 105232.8838584752 105091.63547500195 93045.9000205269 94897.63002265763 84935.77600001381 83315.95333336279 79273.83037534224 99302.15930568223 79503.83751122832 73197.58269324592 1.4376551791263625 1.4357254926766723 1.2711608306856343 1.2964585240519702 1.1603631277819644 1.1382336720396986 1.0830115894340455 1.3566316762376502 1.0861538671899926 1.0 16.159508384697414 -1.522878745280478 0.24056794763571346 1.0749205906322452 3.4914706810977973 0.6615013402701859 0.08549546815772012 32.63760248322155 0.4365174335937716 0.11940539407186657 31.5120453660032 0.029999999999990302 1.522878745280478 2.4165500904655524 RSS(ph)MGSTAVATDVK ddPTM_PC-9_Lapatinib_30min_R1 2 RSSMGSTAVATDVK 14 1 Q6UXY1;B0QYF0;Q6UXY1-2 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 RS(0.047)S(0.952)MGS(0.001)TAVATDVK;RS(0.029)S(0.969)MGS(0.002)TAVATDVK 111.11 0.00041459 27520800.0 102967.0 94962.0 113759.0 101376.0 108947.0 98421.0 89571.0 82149.0 98504.0 83936.0 True False 101498.67169816472 94742.12132344802 104406.174142439 108831.5292204221 102538.95165804314 94211.7632605567 94208.54810573108 85965.94243966864 87409.44222689481 98444.22576231015 1.0310271721088997 0.9623938894313546 1.0605616869243684 1.1055146036009436 1.0415943735046436 0.957006493077892 0.9569738334190778 0.8732451474323151 0.8879082703940564 1.0 16.587018967002976 -6.965198416090352 2.266347691361398 0.9180744937422727 1.0408784689862671 0.5554715306620379 0.04700660538645563 0.23415356242032184 2.4287571729775626 0.020943174775783585 0.016906187846275178 1.0834318135127379e-07 6.965198416090352 0.12280397524399445 RSS(ph)MGSTAVATDVKK ddPTM_PC-9_AZD4547_30min_R2 2 RSSMGSTAVATDVKK 15 2 Q6UXY1;Q6UXY1-2 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 RS(0.042)S(0.899)MGS(0.029)T(0.029)AVATDVKK;RS(0.074)S(0.809)MGS(0.074)T(0.043)AVATDVKK 81.51 0.014528999999999999 62838000.0 130236.0 88104.0 156542.0 183501.0 175338.0 154842.0 139240.0 159601.0 121979.0 142987.0 True False 171648.3389229162 116581.89503237644 154466.15079727408 141197.67951218868 150995.34525418686 145159.7052621153 151632.09025637776 134938.33271612454 128426.56091493585 137981.06865185543 1.2439991993105066 0.8449122489877801 1.119473506811378 1.0233119723724506 1.0943192912584854 1.0520262430230378 1.0989340185425414 0.977948163719415 0.930754937396326 1.0 17.074110813645703 -7.866832223488743 6.256032406183479 0.9623516364848012 1.0599987891500873 0.18115625711589356 0.09499391672916317 0.3619109999397408 18.70365156075989 0.0490155456917843 0.0232536174270005 1.3588382911942675e-08 7.866832223488743 0.09764715266528612 RSS(ph)MGSTAVATDVKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSMGSTAVATDVKK 15 2 Q6UXY1;Q6UXY1-2 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 RS(0.058)S(0.694)MGS(0.041)T(0.194)AVAT(0.013)DVKK 64.346 0.032579000000000004 36238000.0 165770.0 109740.0 135620.0 171730.0 168540.0 171400.0 177760.0 225180.0 148150.0 122930.0 True False 193831.5868932584 120634.26195360621 138853.69514171447 162108.52485617224 135515.79687451312 162411.48226754472 160921.28592904858 219269.26359793142 150316.4134777358 145216.23588665572 1.334779032866187 0.8307215871355029 0.9561857480598289 1.1163250711353054 0.9332000381850278 1.1184113214056193 1.1081494086835508 1.5099500566112705 1.0351212628528732 1.0 17.147843237162256 -7.225428340980566 2.670854568678245 1.2123915807872294 1.0255426154156306 0.07783768554316517 0.18188623896052786 0.49844578056699756 7.036970118198171 0.07854227178765405 0.05424385468953339 5.9507493661249234e-08 7.225428340980566 -0.18684896537159879 RSS(ph)MSLYTAASVIDTASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSMSLYTAASVIDTASK 18 1 Q96PE2;A0A2R8Y4D7 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 RS(0.095)S(0.403)MS(0.403)LY(0.08)T(0.019)AASVIDTASK 73.928 0.012128 0.0 22908.0 20594.0 20064.0 22889.0 25846.0 23467.0 18805.0 25504.0 18439.0 14352.0 True False 26785.871946376046 22638.436218995477 20542.40185314374 21606.603537139224 20781.661837063424 22236.349208707536 17023.654263589993 24834.547023721694 18708.635491839206 16953.903989630508 1.5799235363582955 1.3352934069251419 1.2116620375878062 1.274432340206388 1.2257744204387429 1.311576921888193 1.0041141128321918 1.464827631376892 1.1035001438773007 1.0 14.049329901758059 -1.5228819559592746 0.8826400643062275 1.2067889634930669 168.3822366202498 0.43636962551446723 0.13284948601534377 758.0192550024642 1.8164211629529143 0.04173701401142047 254993.9194519442 0.029999778214976052 1.5228819559592746 167.17544765675675 RSS(ph)MSMEETEHTC ddPTM_PC-9_AZD4547_30min_R2 1 RSSMSMEETEHTC 13 1 O75030-11;O75030-10;O75030-9;O75030-12;O75030-4;O75030-3;O75030-8;O75030-7;O75030-6;O75030-2;O75030-5;O75030 O75030-11 MITF Microphthalmia-associated transcription factor 1 RS(0.123)S(0.801)MS(0.067)MEET(0.009)EHTC 79.639 0.0083031 1179700.0 449.92 984.99 2136.5 3736.1 2629.9 1991.7 2679.9 2448.8 1179.9 3297.6 True False 592.9852010826378 1303.3687549707224 2108.1686140356996 2874.7998671695964 2264.783780378389 1867.1586841461333 2918.40590834579 2070.3942278259246 1242.2671051864083 3182.152027711323 0.1863472253741209 0.4095872050173967 0.6624977674470013 0.9034137408064751 0.7117145129006528 0.5867597361427879 0.917117058811541 0.6506270630052203 0.3903858440352001 1.0 11.63578704691366 -5.081144165308303 2.283525949117958 0.7261178372877893 0.18348253731809352 0.5318793412334573 0.1683646056933808 0.2860128887768866 2.576632242907277 0.04538694353034944 0.23989393100526366 8.295753418707203e-06 5.081144165308303 -0.5426352999696958 RSS(ph)PESDR ddPTM_PC-9_AZD4547_30min_R2 1 RSSPESDR 8 1 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 RS(0.238)S(0.758)PES(0.005)DR 58.63 0.035256 387830.0 0.0 0.0 681.11 0.0 0.0 736.51 431.83 0.0 0.0 674.35 True False 0.0 0.0 672.078036370632 0.0 0.0 690.4559132703062 470.26203343444234 0.0 0.0 650.7412117561653 0.0 0.0 1.0327884944567822 0.0 0.0 1.061029946769411 0.7226559881851328 0.0 0.0 1.0 9.345940112975128 -5.097412410787922 24.9999835831749 0.44219814171863975 2.8989628468111363e-07 0.156949946474077 0.4363151024564787 81.17830005224114 20820.66572492708 0.11344158836978582 0.30013853855500966 7.990750841698306e-06 5.097412410787922 -0.44219785182235505 RSS(ph)PPGHYYQK ddPTM_PC-9_AZD4547_30min_R2 1 RSSPPGHYYQK 11 1 D6RI08;D6RDK1;D6RIV2;D6R9T5;D6RG39;D6RIT9;D6RDK6;D6RBN5;Q9NX40-3;Q9NX40-2;Q9NX40-4;Q9NX40 D6RI08 OCIAD1 OCIA domain-containing protein 1 1 RS(0.464)S(0.536)PPGHYYQK 75.589 0.0098825 66151000.0 53336.0 34952.0 76491.0 103710.0 89293.0 61114.0 70153.0 81739.0 62097.0 68038.0 True False 70295.73854228207 46249.55047638727 75476.6793616684 79801.26180352739 76896.20825937396 57292.531918916895 76396.48109563124 69108.11572536065 65379.320646461936 65656.01032915559 1.0706672274155247 0.7044221883803595 1.149577608862898 1.2154448831638858 1.1711983087895153 0.8726167129511865 1.1635870153033985 1.0525786653635898 0.9957857676501128 1.0 16.002639464927597 -5.285474465065602 24.896157371083778 1.0834925923748053 0.8875446212134303 0.260771504758433 0.127687746068189 818.5709637543803 847895.6164330582 0.0329049649930893 0.0685551145575022 5.182335613581477e-06 5.285474465065602 -0.19594797116137508 RSS(ph)PPGHYYQK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSPPGHYYQK 11 1 D6RI08;D6RDK1;D6RIV2;D6R9T5;D6RG39;D6RIT9;D6RDK6;D6RBN5;Q9NX40-3;Q9NX40-2;Q9NX40-4;Q9NX40 D6RI08 OCIAD1 OCIA domain-containing protein 1 1 RS(0.47)S(0.53)PPGHYYQK 77.89399999999999 0.0087077 8772400.0 45937.0 31425.0 39790.0 28982.0 29427.0 35968.0 23733.0 25342.0 44307.0 24921.0 True False 45281.92995618591 31352.23734324626 36518.61979384173 31113.43296111782 27696.16171570796 34429.73248550318 24961.778613539147 26519.48183551942 39316.67908660589 29228.5616448548 1.5492356588185734 1.0726575506586824 1.2494155626802876 1.064487310021115 0.9475718323820909 1.1779482310435196 0.8540200820293615 0.9073139539929339 1.3451458735577888 1.0 14.835091214547235 -1.8034731686889711 0.9623866503193331 1.041160779925853 199.99909549526257 0.4795774860661466 0.14790905906245094 610.7181282171168 1.8462716070759195 0.046813304551181 266444.69876081625 0.015722689264013476 1.8034731686889711 198.9579347153367 RSS(ph)PPPPPSGSSSR ddPTM_PC-9_Lapatinib_30min_R1 1 RSSPPPPPSGSSSR 14 1 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 RS(0.342)S(0.658)PPPPPSGSSSR 58.688 0.028612000000000002 2464200.0 7088.2 8332.4 8423.2 6007.8 6340.3 6946.3 7457.2 7329.7 5603.1 5408.2 True False 6987.120968183316 8313.10683974113 7730.677010492279 6449.633653433289 5967.3760195094055 6649.2229416161745 7843.297327640164 7670.264620385394 4972.01987474127 6343.000164026475 1.1015482874823006 1.3105954004049798 1.2187729482234348 1.016811207102212 0.9407813125013973 1.0482772772616975 1.2365280032818595 1.2092486870623669 0.783859332518932 1.0 12.630949664140166 -2.0524514749275156 0.1940291884145975 0.9849698100463167 1.898459713444423 0.17736898501890452 0.13819083687337574 86.44275086960454 1.2253572348019868 0.29344863007275185 22.80052811310491 0.008862342398342148 2.0524514749275156 0.9134899033981063 RSS(ph)PSARPPDVPGQQPQAAK ddPTM_PC-9_AZD4547_30min_R2 1 RSSPSARPPDVPGQQPQAAK 20 2 A0A0A6YYC7;Q96JP5-2;Q96JP5 A0A0A6YYC7 ZFP91-CNTF;ZFP91 E3 ubiquitin-protein ligase ZFP91 1 RS(0.144)S(0.665)PS(0.19)ARPPDVPGQQPQAAK 59.538999999999994 0.0048656 9391600.0 13878.0 10629.0 14015.0 18226.0 18033.0 14988.0 13420.0 16947.0 13602.0 14882.0 True False 18290.9153196676 14064.616388576333 13829.151942761677 14024.27728889298 15529.429222237904 14050.797990652332 14614.354002015194 14328.230553318346 14320.97395096664 14360.985709728264 1.2736531941033244 0.979362884474485 0.9629667644188018 0.9765539477831807 1.0813623476916439 0.9784006665457645 1.01764282044479 0.9977191568133287 0.9972138570728805 1.0 13.809867155850474 -4.758864276949943 24.99999911810438 0.9996347701842488 1.273653555643489 0.874368957980773 0.031228936118475065 23.272484899072744 225891.75292296012 0.007958898384916644 0.052696212700834945 1.7423512972671857e-05 4.758864276949943 0.2740187854592401 RSS(ph)PSARPPDVPGQQPQAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSPSARPPDVPGQQPQAAK 20 2 A0A0A6YYC7;Q96JP5-2;Q96JP5 A0A0A6YYC7 ZFP91-CNTF;ZFP91 E3 ubiquitin-protein ligase ZFP91 1 RS(0.179)S(0.792)PS(0.028)ARPPDVPGQQPQAAK 115.87 5.2737e-05 37115000.0 10815.0 11312.0 12794.0 12192.0 13936.0 11902.0 14360.0 8687.1 10458.0 8434.5 True False 12645.76589401332 12434.980601596428 13099.057481515198 11508.92176699731 11205.34084041306 11277.838167726464 12999.716842603144 8459.072829743282 10610.928465407795 9963.608082534736 1.2691954349529417 1.24803991672392 1.314690157722744 1.1550957917715934 1.1246268166704554 1.131903028933409 1.3047198098237545 0.8489969456517702 1.0649684710107927 1.0 13.282452559100758 -7.157484885870708 0.5216607935471924 0.9684376503821688 1.2796334442015913 0.4773734387276972 0.10122771451774296 0.8144122633587165 0.47283925509997576 0.09606141096879477 0.08899174338332821 6.958491709220193e-08 7.157484885870708 0.31119579381942253 RSS(ph)PSSSSTQPQEESR ddPTM_PC-9_AZD4547_30min_R2 1 RSSPSSSSTQPQEESR 16 1 Q4G0A6 Q4G0A6 FAM188B Protein FAM188B 1 RS(0.005)S(0.995)PSSSSTQPQEESR 187.5 2.225e-08 8467700.0 3976.7 4035.5 5239.7 7263.0 6004.0 3758.0 3488.4 5402.8 4031.6 5039.5 True False 5241.207879501521 5339.896456496363 5170.218154440839 5588.6275622314115 5170.448236583845 3523.0116659241685 3798.8608420737532 4567.9214039929375 4244.702145325472 4863.068638904421 1.0777573315687952 1.0980508096836905 1.063159609362539 1.1491977549982613 1.0632069214940532 0.7244421017914836 0.7811653760514434 0.9393084373618925 0.8728443829412496 1.0 12.24765123904112 -6.645686310052396 7.125414832040366 0.8552929443486209 1.0957807837360267 0.6994356758434876 0.07441648274890697 0.12340318550494979 7.220388194982853 0.02497784897720281 0.024933534450002535 2.2610683452323574e-07 6.645686310052396 0.2404878393874058 RSS(ph)PSSSSTQPQEESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSPSSSSTQPQEESR 16 1 Q4G0A6 Q4G0A6 FAM188B Protein FAM188B 1 RS(0.042)S(0.759)PS(0.192)S(0.006)SSTQPQEESR 95.62200000000001 0.008792 0.0 3196.3 2639.9 4693.1 4998.5 3022.5 3611.5 2342.6 2650.3 3562.0 3273.2 True False 3737.370460197387 2901.9718255087005 4805.001302680866 4718.450250355651 2430.2628221977943 3422.106582317603 2120.6919690447176 2580.7324332249696 3614.0875113580555 3866.6052493630555 0.9665766788096722 0.7505218760013688 1.242692489354167 1.2203082409648411 0.6285262304958932 0.8850416222036955 0.5484635312575697 0.6674414031921393 0.934692651119067 1.0 11.916851768540695 -6.268417493747453 24.945313409503388 0.7546721434894083 1.0381080172552473 0.33255991641495586 0.18398576798125996 620.9120915465711 2219628.5869415817 0.058284147059548104 0.06750689539103681 5.389922321342761e-07 6.268417493747453 0.283435873765839 RSS(ph)PVPPVPER ddPTM_PC-9_AZD4547_30min_R2 3 RSSPVPPVPER 11 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RS(0.136)S(0.864)PVPPVPER;RSS(1)PVPPVPER;RS(0.229)S(0.771)PVPPVPER 88.706 0.0044382 298277700.0 199191.0 190198.0 231576.0 374932.0 256863.0 249384.0 219448.0 298062.0 215022.0 283162.0 True False 262529.5945698156 251675.78397539223 228505.1509309295 288497.22004165594 221202.00622812103 233789.9790566352 238978.44687289392 252003.36668337553 226387.6239438866 273248.58456780494 0.9607720200456172 0.9210506410251521 0.8362537404991658 1.0558049934566711 0.8095266315029388 0.8555944742638609 0.874582560970569 0.9222494860566879 0.8285042877786981 1.0 18.059854497169134 -4.934232536492235 4.6629141997041215 0.8942140169031295 0.9566249134675306 0.061254104708020174 0.07408751813875344 0.5798699567737107 24.11574644221787 0.017822583643169396 0.08087525526277062 1.1635028823616667e-05 4.934232536492235 0.06241089656440113 RSS(ph)PVPPVPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RSSPVPPVPER 11 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RS(0.004)S(0.996)PVPPVPER;RS(0.011)S(0.989)PVPPVPER;RS(0.061)S(0.939)PVPPVPER;RS(0.149)S(0.851)PVPPVPER;RS(0.068)S(0.932)PVPPVPER 81.565 0.017735 453861000.0 324776.0 362186.0 429218.0 402444.0 531636.0 437307.0 384907.0 465160.0 391038.0 326242.0 True False 379754.16218160593 398141.43247611495 439452.1849383286 379896.3674210524 427465.7421809593 414373.85108502454 348445.82247464097 452950.0428777594 396756.1909787844 385387.09206974966 0.9853837089927125 1.0330948821816195 1.1402877625667698 0.9857527022526652 1.1091854163698716 1.0752146597842687 0.9041450262469537 1.1753119193617978 1.0295004662662057 1.0 18.55594872609427 -4.855588362835486 4.416359449205213 1.0556495273755444 0.9852290868623771 0.06512718873057399 0.07513809219570142 0.545932295115667 17.20525982465597 0.017942699696780078 0.09380733606612236 1.3944779041893362e-05 4.855588362835486 -0.07042044051316732 RSS(ph)PVPPVPER ddPTM_PC-9_Lapatinib_30min_R1 2 RSSPVPPVPER 11 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 RS(0.016)S(0.984)PVPPVPER;RS(0.002)S(0.998)PVPPVPER 74.789 0.01029 502420000.0 413040.0 295000.0 424350.0 351210.0 379120.0 421560.0 323530.0 329810.0 418420.0 262730.0 True False 407149.97385774076 294316.9456247461 389461.58103837044 377039.1550022144 356820.90697859786 403530.861504357 340280.8003555525 345134.1766306005 371293.1334420667 308142.5304342805 1.321304051355469 0.9551325005670287 1.2639007685485122 1.2235868721881218 1.1579735730595595 1.309559121668927 1.1042967677197235 1.1200471942129695 1.2049395872708157 1.0 18.233238294146183 -10.602849500384144 3.7433322783216565 0.9999384269287546 1.1799034737733398 0.22203943406904547 0.10329441489035669 34873031.23519806 55335641.024470426 27007.852882080097 0.02450514269602989 2.495459349043068e-11 10.602849500384144 0.17996504684458525 RSS(ph)PVYVGR ddPTM_PC-9_AZD4547_30min_R2 1 RSSPVYVGR 9 1 P21980;P21980-2;A2A299;P21980-3 P21980 TGM2 Protein-glutamine gamma-glutamyltransferase 2 1 RS(0.19)S(0.81)PVYVGR 63.473 0.026288 38233000.0 11048.0 7821.3 13215.0 15612.0 12641.0 13652.0 10790.0 17646.0 11125.0 8964.1 True False 14561.034187324361 10349.382271142355 13039.760465472391 12012.894602995564 10886.01534954303 12798.338281851184 11750.289097000292 14919.216164740401 11713.044787862367 8650.26958745969 1.6833040912890758 1.1964230902289879 1.5074397778742241 1.3887306611126522 1.2584596629594647 1.4795305686663172 1.3583725892236589 1.7247111218786537 1.3540670229333416 1.0 13.078529380004575 -4.732531743394223 24.20684373414072 1.3912640198010904 1.6833065590187224 0.19856590636838323 0.18537372989890072 3868.656475632872 3239296.622427502 0.043576748799956606 4.375602552083392 1.851263576950111e-05 4.732531743394223 0.292042539217632 RSS(ph)PVYVGR ddPTM_PC-9_Lapatinib_30min_R1 1 RSSPVYVGR 9 1 P21980;P21980-2;A2A299;P21980-3 P21980 TGM2 Protein-glutamine gamma-glutamyltransferase 2 1 RS(0.242)S(0.758)PVYVGR 60.691 0.031617 4879800.0 5157.7 5036.7 7347.9 6442.0 6790.5 5065.4 5949.4 7110.1 5805.6 4400.4 True False 5084.150252193662 5025.0378306039265 6743.784025714246 6915.766169882027 6391.096140636665 4848.764650024125 6257.430821362227 7440.461202696186 5151.712192321735 5161.003276835563 0.9851088983053266 0.9736552296252362 1.3066808261840817 1.3400042199009 1.2383437478759607 0.9395004013632626 1.2124446518853853 1.4416695366367327 0.9981997522544638 1.0 12.333435831283452 -5.243722690766007 24.195784240090074 1.2000889965699904 0.9793819741523775 0.2145451425326308 0.15481673928722417 779.2178438221531 1064175.5710039448 0.03962334725811029 0.10425567077435101 5.705284544528741e-06 5.243722690766007 -0.22070702241761286 RSS(ph)QPS(ph)PTAVPASDSPPTK ddPTM_PC-9_AZD4547_30min_R2 2 RSSQPSPTAVPASDSPPTK 19 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 2 RS(0.154)S(0.846)QPS(0.983)PT(0.016)AVPAS(0.001)DSPPTK;RS(0.289)S(0.711)QPS(0.832)PT(0.168)AVPASDSPPTK 100.93 0.00031818 15336200.0 66361.0 67316.0 90294.0 80688.0 78603.0 87243.0 76518.0 88107.0 86490.0 85650.0 True False 87462.41760545202 89074.5805638729 89096.64256294843 62086.62821717298 67690.3302365422 81787.68141836667 83327.95376499245 74492.08764744304 91061.68482716536 82651.4195698309 1.0582082928600685 1.077713861751826 1.0779807900053315 0.7511864713311663 0.8189856942426946 0.98954962714543 1.0081853911122476 0.9012801962161803 1.1017558476443197 1.0 16.334751978120487 RSS(ph)QPS(ph)PTAVPASDSPPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSQPSPTAVPASDSPPTK 19 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 2 RS(0.195)S(0.788)QPS(0.92)PT(0.048)AVPAS(0.038)DS(0.003)PPT(0.007)K 73.676 0.016816 0.0 17796.0 26946.0 23608.0 19528.0 23685.0 20436.0 26374.0 20865.0 19265.0 16533.0 True False 20808.511312978357 29621.020800089915 24170.90425383857 18433.909470630202 19044.094274195126 19364.300184478077 23875.663788775448 20317.315858294885 19546.71417920072 19530.302024844015 1.0654474921334223 1.5166698785512762 1.23761036685922 0.9438619764907312 0.9751049548527003 0.9915002932287084 1.2224933213221079 1.0402970641442066 1.000840343090231 1.0 14.25342663939246 -5.623071841430395 5.60913176601528 1.0323316215038105 1.3109320700744878 0.4567727310077544 0.12418453324498868 0.166619144702891 7.759236513770907 0.033305272743712463 0.05858640803700123 2.381925416267047e-06 5.623071841430395 0.27860044857067723 RSS(ph)QPS(ph)PTAVPASDSPPTK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSQPSPTAVPASDSPPTK 19 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 2 RS(0.437)S(0.563)QPS(0.876)PT(0.112)AVPAS(0.009)DS(0.002)PPTK 119.2 3.8892e-05 7995500.0 38364.0 58742.0 53598.0 51202.0 64727.0 58018.0 57140.0 54393.0 59265.0 59909.0 True False 37816.922324904044 58605.98650809775 49191.37933426311 54967.5658848649 60919.88511817817 55536.70538656367 60098.42961183277 56920.297351409055 52589.95161188297 70264.19082627531 0.5382104579899666 0.8340804301439706 0.7000917360008646 0.7822984259616602 0.8670118363534497 0.7903984196427365 0.8553208811643918 0.8100897011984616 0.7484602184049766 1.0 16.1005020065506 -1.6662571047871972 0.08354887260426538 1.0908124511361657 2.3438544871304152e-26 0.5051232930520511 0.08016014027853019 161.15334760895146 1.0083389455614975 1.9402375276526052 20.24174799443288 0.021564673903089453 1.6662571047871972 -1.0908124511361657 RSS(ph)QPSPTAVPAS(ph)DSPPTK ddPTM_PC-9_AZD4547_30min_R2 1 RSSQPSPTAVPASDSPPTK 19 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 2 RS(0.066)S(0.893)QPS(0.024)PT(0.023)AVPAS(0.682)DS(0.171)PPT(0.141)K 79.408 0.002111 3671800.0 15565.0 9861.7 17528.0 15343.0 15088.0 16913.0 11045.0 18227.0 12771.0 16585.0 True False 20514.34622788775 13049.30166894565 17295.567267408245 11805.908396986984 12993.291637837605 15855.427436342594 12027.98360299983 15410.435964792194 13446.048987486765 16004.36419808112 1.2817970132388865 0.8153589550599096 1.0806781858589507 0.7376680667141079 0.8118592826946206 0.9906939907205821 0.7515439822621602 0.9628896077383606 0.8401489007041535 1.0 13.96617774393715 -4.755317486284423 24.997881550909668 0.8846204936901836 1.2817976656540953 0.5366491359046145 0.10977348633423283 150.93958532491723 616280.9982983696 0.025698721496583986 0.23036715690922788 1.7566389725301694e-05 4.755317486284423 0.39717717196391167 RSS(ph)QPSPTAVPAS(ph)DSPPTK ddPTM_PC-9_Lapatinib_30min_R1 2 RSSQPSPTAVPASDSPPTK 19 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 2 RS(0.439)S(0.523)QPS(0.038)PT(0.011)AVPAS(0.83)DS(0.086)PPT(0.073)K;RS(0.197)S(0.801)QPS(0.002)PTAVPAS(0.767)DS(0.216)PPT(0.017)K 117.94 4.4469e-05 18042500.0 64087.0 87279.0 85891.0 79860.0 102476.0 81498.0 77915.0 87256.0 88055.0 79250.0 True False 63173.107627883604 87076.91083790563 78829.37352884814 85733.1708051502 96448.56315556777 78012.520521117 81949.05745897704 91310.23230368868 78137.31863974263 92948.25690601254 0.6796588739879545 0.9368321013911654 0.8480995357294205 0.9223752403645602 1.037658654030432 0.8393112804686776 0.8816631982872183 0.9823770272100939 0.8406539427496049 1.0 16.504140189539484 -4.758700172158242 24.99944850976517 0.9180749440097414 0.6796585557596747 0.5436517590621055 0.06628511697952597 57.485835496910845 524545.9243548545 0.01595805787960946 0.10696215176373232 1.7430097956745902e-05 4.758700172158242 -0.23841638825006672 RSS(ph)QPSPTAVPASDS(ph)PPTK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSQPSPTAVPASDSPPTK 19 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 2 RS(0.144)S(0.809)QPS(0.047)PTAVPAS(0.045)DS(0.937)PPT(0.018)K 112.17 8.512799999999999e-05 7024000.0 15395.0 19994.0 21657.0 13951.0 20247.0 18009.0 18189.0 17568.0 22725.0 19353.0 True False 15175.464476902762 19947.70512142771 19876.445058437563 14977.003079171724 19056.111267133576 17238.797051029425 19130.73742053948 18384.273415137133 20165.471195141134 22698.140263748457 0.6685774385287294 0.8788255288600225 0.8756860618304723 0.6598339293502262 0.8395450484359012 0.7594805940362334 0.8428328135364231 0.8099462423579669 0.8884195339715877 1.0 14.470286476969628 -8.642787998401628 0.8775789693330316 1.0009461373262887 0.786882845658522 0.460925735559645 0.07225156312368355 0.6973170329339137 1.1480723129993495 0.06803051352515956 0.02357456364953601 2.276208294609288e-09 8.642787998401628 -0.21406329166776672 RSS(ph)QPSPTAVPASDSPPTK ddPTM_PC-9_AZD4547_30min_R2 2 RSSQPSPTAVPASDSPPTK 19 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 RS(0.047)S(0.951)QPS(0.002)PTAVPASDSPPTK;RS(0.006)S(0.994)QPSPTAVPASDSPPTK 184.97 1.1512e-10 51642000.0 87714.0 88589.0 112118.0 102103.0 88227.0 93771.0 87853.0 107110.0 101682.0 99749.0 True False 115605.22743546043 117223.66179768463 110631.24206340028 78564.73082562484 75978.20395887461 87907.48454640093 95671.74680618796 90558.61064294139 107056.70293208264 96256.81787123285 1.201008198610002 1.2178219100749839 1.1493340888475738 0.8161991281565579 0.789328025164037 0.9132598239846116 0.9939217701355184 0.9408020402677947 1.1121986504405048 1.0 16.554601109965525 -5.632441874718993 5.941570438082509 0.9312851816740448 1.2028475406603667 0.6391563301346398 0.08708703385020408 0.13359341790036766 6.454163620218936 0.02580233861145054 0.04519175271699997 2.3310850831163105e-06 5.632441874718993 0.27156235898632186 RSS(ph)QPSPTAVPASDSPPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RSSQPSPTAVPASDSPPTK 19 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 RS(0.374)S(0.518)QPS(0.054)PT(0.054)AVPASDSPPTK;RS(0.005)S(0.981)QPS(0.01)PT(0.005)AVPASDSPPTK;RS(0.177)S(0.51)QPS(0.305)PT(0.008)AVPASDSPPTK;RS(0.24)S(0.76)QPSPTAVPASDSPPTK 190.3 1.2270999999999999e-11 229916300.0 346896.0 411905.0 388770.0 376310.0 386185.0 301043.0 333001.0 324222.0 304952.0 230114.0 True False 405618.64129169064 452796.20621469064 398039.75121843617 355226.57071348134 310514.82150221843 285255.7751240863 301456.7345615388 315711.5160416042 309411.3460874967 271831.84661857865 1.492167479040214 1.6657217020271817 1.4642866763766145 1.3067879099976027 1.142304793808497 1.0493832075692862 1.1089824033183586 1.1614221069711357 1.1382453893330895 1.0 18.052354960222885 -5.902962831317796 1.7033728125070537 1.1016736800090725 1.581545256649202 0.9153656940657013 0.06068267214531057 0.09288546341873291 0.5483262488866602 0.019560242940600277 0.03577536694024422 1.2503660370325096e-06 5.902962831317796 0.4798715766401296 RSS(ph)QPSPTAVPASDSPPTK ddPTM_PC-9_Lapatinib_30min_R1 3 RSSQPSPTAVPASDSPPTK 19 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 RS(0.001)S(0.998)QPSPTAVPASDSPPTK;RS(0.366)S(0.616)QPS(0.017)PT(0.001)AVPASDSPPTK;RS(0.004)S(0.996)QPSPTAVPASDSPPTK 257.71 1.9405999999999994e-65 139702000.0 291070.0 373036.0 437451.0 352014.0 367512.0 376529.0 339689.0 368118.0 397669.0 363281.0 True False 286919.28842429904 372172.25806126336 401485.46738969226 377902.2838442802 345895.66671639174 360425.73240196885 357276.43430895807 385222.10616082855 352879.32957978337 426073.63680849556 0.673403054395639 0.873492809480116 0.9422912677654008 0.8869412495806056 0.8118213304801563 0.8459235711031964 0.838532130232551 0.9041209614524255 0.828212072032961 1.0 18.700743262347466 -14.522878745280327 0.21432465344477256 1.7222166161548438 0.8309352662197157 0.3309996314565544 0.06746426185334313 194.39696527505842 1.9364981301548603 60.600154667521906 0.14037001280258762 3.0000000000000748e-15 14.522878745280327 -0.8912813499351281 RSS(ph)QPSPTAVPASDSPPTKQEVK ddPTM_PC-9_AZD4547_30min_R2 4 RSSQPSPTAVPASDSPPTKQEVK 23 2 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 RS(0.035)S(0.944)QPS(0.016)PT(0.005)AVPASDSPPTKQEVK;RS(0.365)S(0.575)QPS(0.059)PT(0.001)AVPASDSPPTKQEVK;RS(0.404)S(0.539)QPS(0.012)PT(0.045)AVPASDSPPTKQEVK;RS(0.181)S(0.806)QPS(0.012)PT(0.001)AVPASDSPPTKQEVK 106.36 6.0253e-06 41370500.0 35737.9 28464.7 47036.0 73660.0 54092.1 40023.1 33547.700000000004 36622.100000000006 34098.0 48346.0 True False 47101.80880550139 37665.357617453075 46412.27190722356 56678.825035655515 46582.34561261106 37520.44923002916 36533.38030949367 30962.99593713813 35900.35066755331 46653.421255377136 1.0096110325472125 0.8073439547182594 0.9948310468629183 1.2148910735913687 0.9984765181019198 0.8042378933936096 0.783080411391757 0.6636811428608663 0.7695116392651599 1.0 15.509695262280957 -6.780539720147074 5.097324755397995 0.779397244791957 1.0061482802867379 0.40357585196940526 0.12062303853683651 0.18281943338625603 12.705960749569169 0.04444428023546848 0.04078965573570338 1.6575257342394094e-07 6.780539720147074 0.22675103549478082 RSS(ph)QPSPTAVPASDSPPTKQEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RSSQPSPTAVPASDSPPTKQEVK 23 2 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 RS(0.172)S(0.793)QPS(0.031)PT(0.004)AVPASDSPPTKQEVK;RS(0.07)S(0.926)QPS(0.003)PTAVPASDSPPTKQEVK;RS(0.333)S(0.412)QPS(0.114)PT(0.141)AVPASDSPPTKQEVK 132.79 1.425e-06 26802400.0 54323.0 23101.8 40881.0 67656.0 59323.0 71596.0 60931.0 89691.0 67334.0 46852.0 True False 63518.810971843275 25395.194029522663 41855.75808205587 63865.453663711436 47699.084003718686 67841.37972244532 55159.17457776128 87336.70628546958 68318.6323665871 55345.896719772056 1.1476697413261259 0.45884510929697075 0.7562576552690148 1.1539329462322327 0.8618359594972181 1.2257707209251758 0.9966262694602964 1.5780159228004516 1.2343938108456123 1.0 15.756188740793428 -6.4992232520055655 0.9213860142020837 1.264193084383794 0.7767545173477303 0.3111887089880846 0.24051143194757357 0.604317672862007 1.1185930010040033 0.12751482649725723 0.15619393012332833 3.1679385442404563e-07 6.4992232520055655 -0.4874385670360638 RSS(ph)QPSPTAVPASDSPPTKQEVK ddPTM_PC-9_Lapatinib_30min_R1 2 RSSQPSPTAVPASDSPPTKQEVK 23 2 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 RS(0.141)S(0.703)QPS(0.153)PT(0.003)AVPASDSPPTKQEVK;RS(0.314)S(0.425)QPS(0.15)PT(0.111)AVPASDSPPTKQEVK 87.35600000000001 9.0562e-06 42311000.0 196530.0 97680.0 131519.0 97672.0 87414.0 91409.0 62720.0 60770.0 113045.0 69181.0 True False 193727.4461608123 97453.82796144117 120706.01549802122 104855.12470424078 82272.48038253633 87499.65015478652 65967.334708683 63593.59605179213 100312.6816833765 81138.84367211179 2.3876042274361167 1.2010748927512385 1.4876477163737183 1.2922925686243234 1.0139715660110422 1.078394098249406 0.8130179298002076 0.7837626613065706 1.2363089876995 1.0 16.308105122069023 -1.5228787452803427 0.6676404626133257 0.9883601456047071 128.2030480634021 0.7891213764990499 0.20052187209165653 108.13135611965491 0.6522856587205681 0.08257187529120638 20409.19294547137 0.02999999999999964 1.5228787452803427 127.21468791779739 up RSS(ph)SIASMPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSSIASMPR 10 1 E7ERA6 E7ERA6 RNF223 RING finger protein 223 1 RS(0.239)S(0.755)S(0.002)IAS(0.005)MPR 53.597 0.045021 0.0 6104.7 7990.3 11118.0 9760.7 12044.0 12663.0 12369.0 12531.0 11612.0 9006.0 True False 7138.105136678968 8783.52417794695 11383.095285249801 9213.839623616363 9684.064658577412 11998.929988062537 11197.318776194878 12202.074527691992 11781.803532254278 10638.716508543232 0.6709554795399276 0.8256187831392535 1.0699688516099484 0.8660668433280794 0.9102662572877843 1.1278550357486272 1.0525065469319603 1.1469498710575974 1.1074459520368938 1.0 13.377036489180643 -3.9507553786412597 0.46868931999609115 1.0887072287450759 2.98881602732477e-14 0.6764119265794208 0.0837700989308252 6.25429384949221 0.5876933913648053 0.05632551316608097 4.436749150340446 0.00011200685973336466 3.9507553786412597 -1.0887072287450459 RSS(ph)SSGDQSSDSLNSPTLLAL ddPTM_PC-9_AZD4547_30min_R2 1 RSSSSGDQSSDSLNSPTLLAL 21 1 P15408;P15408-3;P15408-2 P15408 FOSL2 Fos-related antigen 2 1 RS(0.192)S(0.732)S(0.052)S(0.014)GDQS(0.002)S(0.002)DS(0.004)LNS(0.002)PTLLAL 84.581 0.00068399 4479500.0 3545.5 1543.0 8584.9 11001.0 10495.0 8611.0 6300.0 10346.0 8571.9 8465.0 True False 4672.8952490186975 2041.7445749904298 8471.058616725988 8464.889413755716 9037.950406886643 8072.5528087474795 6860.687795282837 8747.263427428543 9024.99313411931 8168.64292654547 0.5720528233439225 0.2499490543717384 1.0370215337969744 1.0362663039472004 1.1064200612216997 0.9882367097372161 0.8398809761885664 1.0708343486287963 1.1048338402442561 1.0 12.995880705044769 -5.269874320143625 24.9805382295565 1.0211471535804277 0.4110009335285277 0.8527091300646717 0.10172881729653707 180.443617735337 534394.6003474982 0.02634634441591827 0.056291608997360895 5.3718722971973984e-06 5.269874320143625 -0.6101462200519001 RSS(ph)SSGDQSSDSLNSPTLLAL ddPTM_PC-9_Lapatinib_30min_R1 2 RSSSSGDQSSDSLNSPTLLAL 21 1 P15408;P15408-3;P15408-2 P15408 FOSL2 Fos-related antigen 2 1 RS(0.202)S(0.555)S(0.202)S(0.04)GDQSSDS(0.001)LNSPTLLAL;RS(0.18)S(0.559)S(0.18)S(0.059)GDQS(0.011)S(0.011)DS(0.001)LNSPTLLAL 77.357 0.0017992999999999998 14096500.0 11050.4 11284.599999999999 14511.0 9752.8 10227.0 10711.8 7365.0 6512.6 7609.1 8243.5 True False 10892.819269604828 11258.471202023751 13317.961594079856 10470.053446387066 9625.467967055616 10253.681284425402 7746.323662778234 6815.199171415194 6752.083030624795 9668.377991226704 1.1266439189168245 1.1644632855935022 1.377476305349756 1.0829172644975011 0.995561817689583 1.0605378992970502 0.8012019875316643 0.7048958137134743 0.6983677134625665 1.0 13.239058161924477 -6.850354980868345 1.1254024484639789 0.7689687129780365 1.202774497735047 0.6735068424837195 0.1162210667918374 0.27250151122657273 0.7266402659776859 0.06518296261184704 0.053964977390539265 1.4113834453754376e-07 6.850354980868345 0.4338057847570105 RSS(ph)T(ph)AWLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSTAWLPR 9 1 J3KRP4 J3KRP4 COG1 2 RS(0.214)S(0.945)T(0.841)AWLPR 101.39 0.0053851 0.0 13739.0 18392.0 19500.0 20736.0 21460.0 20338.0 18553.0 14583.0 18292.0 17808.0 True False 16064.741342380843 20217.83621150649 19964.95395416182 19574.229147019047 17255.06705189898 19271.439476997228 16795.52552791199 14200.211701965703 18559.485894935882 21036.449431949575 0.7636622042302519 0.9610859606754836 0.9490648133729072 0.9304911083184148 0.8202461688089085 0.9160975353439778 0.7984011552065156 0.6750289181594883 0.8822537260849852 1.0 14.360603604180758 -7.2648790129106295 24.41507865481584 0.8118400220634605 0.8946741565327685 0.03424722796430235 0.09543295767846788 437.7567620209538 3107241.314322714 0.037757892097084335 0.026618600790597077 5.43401692919092e-08 7.2648790129106295 0.08283413446930799 RSS(ph)TS(ph)GDTEEEEEEEVVPFSSDEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSTSGDTEEEEEEEVVPFSSDEQK 25 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 2 RS(0.242)S(0.602)T(0.254)S(0.447)GDT(0.447)EEEEEEEVVPFS(0.003)S(0.004)DEQK 46.46 0.031718 2942900.0 4606.3 3607.0 4925.2 6111.8 6016.8 7289.3 9274.7 8753.9 4998.7 4393.8 True False 5386.055611427972 3965.07912216746 5042.635446925015 5769.375660722947 4837.851231960198 6907.036275920732 8396.133272986868 8524.119400523738 5071.796530888695 5190.361158698337 1.0377034365713989 0.7639312565990766 0.9715384522855882 1.1115557249911716 0.9320837383064605 1.330742902995388 1.617639508363709 1.642297932628152 0.9771567672875819 1.0 12.341619213174901 -6.793157814726948 5.961197682531347 1.376078203785699 0.9603355985641482 0.3657295899941706 0.22345391860863825 0.1703450621561605 17.038683423445132 0.07831628757997676 0.0706808852853429 1.610060462134502e-07 6.793157814726948 -0.4157426052215507 RSS(ph)TSGDT(ph)EEEEEEEVVPFSSDEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSTSGDTEEEEEEEVVPFSSDEQK 25 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 2 RS(0.178)S(0.439)T(0.305)S(0.387)GDT(0.691)EEEEEEEVVPFSSDEQK 65.782 0.0028991 7985300.0 18803.0 21052.0 19788.0 22450.0 28049.0 23963.0 28445.0 25855.0 25643.0 24566.0 True False 21985.97652382175 23141.903432178922 20259.82096640791 21192.199283882026 22552.999801431255 22706.338095549436 25750.483676033895 25176.333645636925 26017.98036321019 29019.621335651 0.7576245144457374 0.7974571123624131 0.6981421546503243 0.7302713925438827 0.7771638210083943 0.7824477732813967 0.8873473357282947 0.8675624452310635 0.8965651226898246 1.0 14.824741073980205 -7.836745704853089 0.6052537182300691 0.9897735984770066 0.7398072893190346 0.8679070482098578 0.031601343390132944 0.26956729461952833 0.21003155133526183 0.03263837125845012 0.017745760933937264 1.4563115541350784e-08 7.836745704853089 -0.24996630915797202 RSS(ph)TSGDT(ph)EEEEEEEVVPFSSDEQK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSTSGDTEEEEEEEVVPFSSDEQK 25 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 2 RS(0.168)S(0.414)T(0.347)S(0.389)GDT(0.681)EEEEEEEVVPFSS(0.001)DEQK 55.668 0.021287999999999998 12806000.0 40522.0 38565.0 36826.0 43780.0 45269.0 44578.0 38353.0 45742.0 48955.0 41657.0 True False 39944.148849175326 38475.70511192652 33798.30843247088 46999.72724579868 42606.36642227834 42671.50285639349 40338.730677329746 47867.340309380845 43441.172380996024 48857.35694553655 0.8175667155655356 0.7875109813004639 0.6917752114619574 0.9619785060864292 0.8720563101637597 0.8733895061896471 0.8256429164249942 0.9797365903919174 0.8891429069612139 1.0 15.576288199259709 -5.072770359554208 0.1447693813152481 1.0477507218168503 0.551364858281009 0.45195619759288663 0.06665556116228331 22.574341232595756 0.6208222065773142 0.3976261502343605 2.220078881201356 8.457259186264814e-06 5.072770359554208 -0.49638586353584124 RSS(ph)TSGDT(ph)EEEEEEEVVPFSSDEQKR ddPTM_PC-9_AZD4547_30min_R2 1 RSSTSGDTEEEEEEEVVPFSSDEQKR 26 2 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 2 RS(0.151)S(0.404)T(0.404)S(0.253)GDT(0.787)EEEEEEEVVPFSSDEQKR 70.358 0.00029673 3415200.0 6977.7 7018.1 10933.0 12565.0 9635.9 8545.9 9714.6 10125.0 9008.8 8048.6 True False 9196.463454823794 9286.563578574423 10788.021276504702 9668.33337731484 8298.121612741214 8011.523522038683 10579.18058032614 8560.41389935376 9484.98677617029 7766.820963803179 1.1840704836230138 1.1956711274605036 1.3889880205532807 1.2448250606488227 1.0684064498736523 1.0315061412353814 1.3620991947194097 1.102177318010686 1.22121867111068 1.0 12.923108494845511 -14.522878745171287 0.16028387365276403 0.26735281780177184 1.2522752327206088 0.23654905215599087 0.10911796590390548 209.96953281505043 1.9251751498532672 49.02408914746156 0.4833444660371219 3.0000000007532957e-15 14.522878745171287 0.9849224149188369 RSS(ph)TSGDTEEEEEEEVVPFSSDEQK ddPTM_PC-9_AZD4547_30min_R2 1 RSSTSGDTEEEEEEEVVPFSSDEQK 25 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RS(0.094)S(0.29)T(0.29)S(0.29)GDT(0.036)EEEEEEEVVPFSSDEQK 114.75 4.3178e-09 34603000.0 37766.0 34980.0 39169.0 45695.0 43287.0 42626.0 36108.0 37369.0 33906.0 34539.0 True False 49774.802418400795 46286.6009288174 38649.59346743004 35160.72373071243 37277.34723800877 39960.58948155502 39321.54204953537 31594.479704192654 35698.201939529106 33329.800122853405 1.493402367698913 1.388745229740512 1.1596107184851967 1.0549335309875922 1.118438967548702 1.1989447681732435 1.1797713128970604 0.947934868728154 1.0710595865545485 1.0 15.024525045253451 -5.214827923586257 2.238206403414449 1.0892182329729374 1.4913955843379403 0.8005340026151735 0.07154521612869659 0.1557183894641753 1.4253361950729204 0.02126317701231626 0.08444052104651739 6.097784561584063e-06 5.214827923586257 0.4021773513650029 RSS(ph)TSGDTEEEEEEEVVPFSSDEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSSTSGDTEEEEEEEVVPFSSDEQK 25 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RS(0.129)S(0.276)T(0.276)S(0.276)GDT(0.041)EEEEEEEVVPFSSDEQK;RS(0.173)S(0.449)T(0.173)S(0.173)GDT(0.032)EEEEEEEVVPFSSDEQK 90.06 2.8517e-06 75645000.0 65990.0 58784.0 57690.0 66120.0 64683.0 69752.0 73303.0 75628.0 62264.0 53161.0 True False 77160.80363808939 64619.687030078196 59065.548390543336 62415.51076393234 52008.83048080064 66094.08232862176 66359.20917223804 73642.84513448951 63174.493208084816 62798.66847775557 1.2287012688082892 1.0289977255324714 0.9405541522184571 0.9938986331539983 0.8281836500916117 1.0524758554718956 1.056697710011856 1.1726816335377421 1.0059845971170929 1.0 15.938446349479982 -9.441044321374749 13.028922609889555 1.0000096069227307 1.0293533834666655 0.007464126058108089 0.10569898710061659 0.0 0.0 0.10720764734801284 0.026001673758225066 3.6220603205139135e-10 9.441044321374749 0.02934377654393483 RSS(ph)TSGDTEEEEEEEVVPFSSDEQK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSTSGDTEEEEEEEVVPFSSDEQK 25 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RS(0.104)S(0.294)T(0.294)S(0.294)GDT(0.013)EEEEEEEVVPFSSDEQK 77.657 5.7672e-05 26343000.0 40237.0 32259.0 39747.0 33849.0 38065.0 36223.0 32962.0 39543.0 39417.0 32849.0 True False 39663.21300143789 32184.30626748705 36479.15508785696 36338.368376953884 35826.091538669396 34673.82672993718 34668.611075695335 41380.31213881874 34977.44238058869 38526.90588145885 1.0294938587457627 0.8353722036883271 0.9468488126219508 0.9431945687193581 0.9298979691984758 0.8999899144930823 0.8998545375630508 1.0740626892317637 0.9078705278905269 1.0 15.23357870650932 -7.721213085616039 24.999993005443002 0.993225589934176 0.9234330237162972 0.2142910953181668 0.059123430031513276 205.01266466832755 127411.93214696678 0.025825819551515042 0.014910303271338153 1.900145748908759e-08 7.721213085616039 -0.06979256621787877 RSS(ph)TSGDTEEEEEEEVVPFSSDEQKR ddPTM_PC-9_AZD4547_30min_R2 2 RSSTSGDTEEEEEEEVVPFSSDEQKR 26 2 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RS(0.337)S(0.543)T(0.098)S(0.019)GDT(0.004)EEEEEEEVVPFSSDEQKR;RS(0.182)S(0.505)T(0.114)S(0.114)GDT(0.086)EEEEEEEVVPFSSDEQKR 109.32 1.6156e-10 55754000.0 33435.0 35692.0 42508.0 54373.0 50571.0 46638.0 41472.0 42389.0 39896.0 44919.0 True False 44066.6345087971 47228.74100489854 41944.316145766184 41838.14490447588 43550.089569000935 43721.71848732607 45162.92765809043 35838.75405231671 42004.821110701705 43346.399482279514 1.0166157982005408 1.0895654903057443 0.9676539838773341 0.9652046168581954 1.0046991235524578 1.0086585970121922 1.0419072448347997 0.8267988686573147 0.9690498314138811 1.0 15.40362454220557 -7.727293735800769 24.99997595714179 0.923442881780825 1.01225756816182 0.32565371527784037 0.05331908654058453 185.2749583586891 135650.43751119354 0.024664004617584785 0.014238808910776463 1.8737267811520922e-08 7.727293735800769 0.08881468638099499 RSS(ph)TSSEPTPTVK ddPTM_PC-9_AZD4547_30min_R2 1 RSSTSSEPTPTVK 13 1 Q69YQ0-2;Q69YQ0;F8WAN1;A0A494C1J1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 RS(0.008)S(0.962)T(0.028)S(0.003)SEPTPTVK 201.72 2.8256e-07 77021000.0 60696.0 54345.0 63545.0 89846.0 86967.0 57574.0 54140.0 83737.0 52624.0 63962.0 True False 79996.06544477181 71910.95847560278 62702.351780434605 69133.39280686264 74893.13320969124 53973.888678530646 58958.35511692264 70797.37073483317 55405.59720597476 61722.7098485176 1.296055627517026 1.1650648303045927 1.0158716610842473 1.1200641218853262 1.213380510892944 0.8744575345281432 0.9552133284753804 1.1470230472477143 0.8976533490177836 1.0 15.91351378233944 -6.751561027497974 24.999978538028742 0.9828298769413802 1.1517950546990563 0.48736720564792313 0.09553980389037123 206.7369547156441 523206.01872599084 0.03285440058388285 0.032477003000134785 1.7718990386028216e-07 6.751561027497974 0.16896517775767605 RSS(ph)TSSEPTPTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RSSTSSEPTPTVK 13 1 Q69YQ0-2;Q69YQ0;F8WAN1;A0A494C1J1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 RS(0.019)S(0.907)T(0.068)S(0.005)S(0.001)EPTPTVK;RS(0.004)S(0.992)T(0.004)SSEPTPTVK;RS(0.006)S(0.987)T(0.006)SSEPTPTVK;RS(0.016)S(0.858)T(0.115)S(0.008)S(0.002)EPTPTVK;RS(0.015)S(0.981)T(0.002)S(0.001)S(0.001)EPTPTVK 194.77 1.8204e-06 134903500.0 201509.0 201070.0 207850.0 214376.0 227772.0 185098.0 191415.0 212721.0 175853.0 136156.0 True False 235620.4937158327 221030.90077466337 212805.93227551485 202365.20773636943 183141.7116749831 175391.13503359363 173282.78547540924 207137.29914653007 178424.51744380905 160840.00498969713 1.4649371201581707 1.3742283879487684 1.3230908087148248 1.25817707944819 1.1386577094841208 1.0904695945814513 1.0773612291700012 1.2878468833658554 1.109329221018355 1.0 17.295266760444072 -5.7099659456658065 1.1125781505008212 1.1238591417812178 1.447899698559971 0.7563041803238798 0.07055673391675202 0.30529473422812986 0.7154251681003156 0.026420694763685734 0.07999676601931378 1.949997498921627e-06 5.7099659456658065 0.3240405567787532 RSS(ph)TSSEPTPTVK ddPTM_PC-9_Lapatinib_30min_R1 3 RSSTSSEPTPTVK 13 1 Q69YQ0-2;Q69YQ0;F8WAN1;A0A494C1J1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 RS(0.019)S(0.696)T(0.062)S(0.111)S(0.111)EPT(0.001)PTVK;RS(0.132)S(0.866)T(0.002)SSEPTPTVK;RS(0.15)S(0.526)T(0.173)S(0.15)S(0.002)EPTPTVK 99.915 0.0010941 114846000.0 178170.0 156962.0 176377.0 148204.0 155278.0 155972.0 128166.0 127619.0 155556.0 136839.0 True False 175629.2631276233 156598.56413271654 161875.96389490893 159103.41655405078 146144.853328294 149301.44114849024 134801.80835894562 133548.6446360645 138035.6452027009 160491.43882349378 1.094321693512748 0.9757440352001668 1.0086267845909078 0.9913514248509572 0.910608406277808 0.9302766692290039 0.8399314589434191 0.8321231687812296 0.8600810498964405 1.0 17.29213681542108 -6.210457347185975 1.000223532932815 0.8721981322923646 1.0375233195782103 0.5680123467614342 0.05292885082570065 0.3760477569523998 0.789175268633433 0.02326325657122003 0.03845129995469404 6.159460192713175e-07 6.210457347185975 0.16532518728584567 RSS(ph)VTVEER ddPTM_PC-9_AZD4547_30min_R2 1 RSSVTVEER 9 1 V9GZ26;Q9BQ89 V9GZ26 FAM110A Protein FAM110A 1 RS(0.01)S(0.919)VT(0.071)VEER 75.229 0.038600999999999996 2632700.0 8749.3 10071.0 19122.0 34480.0 25495.0 18305.0 10606.0 20746.0 14815.0 16689.0 True False 11531.395403254624 13326.253800861075 18868.42978590715 26531.16871068966 21955.4593257337 17160.385456291093 11549.913453455516 17540.18239565365 15598.090654578065 16104.723189736247 0.7160256818697595 0.8274748745358177 1.1716084507389888 1.64741538231457 1.3632931821967735 1.0655498547921416 0.7171755339959167 1.0891328083696739 0.9685413695603867 1.0 13.975196243236534 -7.004131136157252 24.81686894479145 0.9426005152106554 1.1626397261980836 0.11798251332330167 0.257566502180601 376.2395549418603 2260187.206181826 0.10429349141234318 0.08985100764729012 9.905328062110359e-08 7.004131136157252 0.2200392109874283 RSS(ph)WECTGSGR ddPTM_PC-9_AZD4547_30min_R2 2 RSSWECTGSGR 11 1 Q8NEV8-2;Q8NEV8;E9PPH6 Q8NEV8-2 EXPH5 Exophilin-5 1 RSS(0.978)WECT(0.022)GSGR;RS(0.209)S(0.791)WECTGSGR 139.74 0.00016788 33988000.0 74288.0 63544.0 103971.0 145474.0 118045.0 84765.0 75114.0 97941.0 87805.0 93015.0 True False 97910.03871360925 84083.35532935313 102592.27660655539 111937.21685089529 101656.48935501979 79464.63115009641 81799.00048490068 82806.46891028208 92446.19304253982 89758.57316156273 1.090815453777035 0.9367724147976998 1.1429802523920738 1.247092204211086 1.1325546493708314 0.8853152222803549 0.9113224241840937 0.922546626952647 1.0299427652012634 1.0 16.45376212201689 -6.754153473445609 24.995685099681307 0.9425781314646052 1.1098605667446673 0.49062527774094356 0.08145782936148388 155.78559259584634 534451.2787401992 0.029888714954749665 0.02930568354449411 1.7613534993355033e-07 6.754153473445609 0.16728243528006204 RSS(ph)WECTGSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSWECTGSGR 11 1 Q8NEV8-2;Q8NEV8;E9PPH6 Q8NEV8-2 EXPH5 Exophilin-5 1 RS(0.011)S(0.977)WECT(0.011)GS(0.001)GR 87.21600000000001 0.015415 9685000.0 42254.0 31958.0 42537.0 52798.0 52920.0 51347.0 50148.0 49209.0 39820.0 33663.0 True False 49406.76764545896 35130.57903693585 43551.24340247083 49839.899233425545 42550.70588939862 48654.27292877257 45397.61839992081 47917.315891245344 40402.292167961234 39765.83542383864 1.2424425922117261 0.8834362125805091 1.0951924670583666 1.253334645235386 1.0700317354301205 1.2235194460319456 1.1416236554835726 1.2049870292054796 1.016005114373658 1.0 15.279241859772107 -4.459954060799654 23.666124048396064 1.1111458329982964 5.292298501747465 0.12743903672851176 0.1085275346025887 1761.0074783711955 641780.1077233121 0.02602559550573631 12052.747978071364 3.467735298412877e-05 4.459954060799654 4.181152668749168 RSS(ph)WECTGSGR ddPTM_PC-9_Lapatinib_30min_R1 3 RSSWECTGSGR 11 1 Q8NEV8-2;Q8NEV8;E9PPH6 Q8NEV8-2 EXPH5 Exophilin-5 1 RS(0.236)S(0.727)WECT(0.037)GS(0.001)GR;RS(0.219)S(0.768)WECT(0.003)GS(0.01)GR;RS(0.015)S(0.983)WECT(0.002)GSGR 104.9 0.0038556 33479200.0 84242.8 65189.8 78412.2 73728.5 75266.1 65633.5 54761.8 50908.0 84146.8 62350.8 True False 83041.48222376243 65038.85702334941 71965.45159584521 79150.73984106594 70839.095976846 62826.50820416123 57597.098052454705 53273.37152879106 74669.30127891316 73128.05270278123 1.1355626077077827 0.8893831384747898 0.9841018451337511 1.0823580953640741 0.9686993343684621 0.8591300586043336 0.7876197426800091 0.7284943268667804 1.0210760237578884 1.0 16.15813732514637 -6.676727757628713 3.951960044322997 0.8560355887711977 1.0118831352274462 0.2902109799297128 0.10255925782499807 0.2628502548688233 7.8374178416127815 0.03478666286207545 0.034152658346779 2.1050976303295605e-07 6.676727757628713 0.15584754645624854 RSS(ph)YLLAITTER ddPTM_PC-9_AZD4547_30min_R2 2 RSSYLLAITTER 12 1 Q9P227;Q9P227-2 Q9P227 ARHGAP23 Rho GTPase-activating protein 23 1 RS(0.042)S(0.957)Y(0.002)LLAITTER;RS(0.245)S(0.755)YLLAITTER 102.72 0.0010638 7550000.0 26956.0 26279.0 35229.0 36361.0 40176.0 33194.0 32095.0 39795.0 30266.0 34827.0 True False 35527.447280368906 34773.172836146165 34761.840441780325 27978.533221849975 34598.255888239895 31118.373932593655 34951.39282374646 33645.597148126704 31865.798970736374 33607.71733051379 1.0571217000838113 1.0346782107862533 1.0343410145924627 0.8325032297402462 1.0294735446619208 0.9259294115860716 1.039981159089692 1.0011271166452749 0.9481690963225324 1.0 15.036504936245237 -5.557866180002347 24.99992109542823 0.9690348532585756 1.043052915335635 0.2656111374320057 0.056460053963019396 228.09838187386933 162984.5728813256 0.01496600283272852 0.02592206464923647 2.7677943598532523e-06 5.557866180002347 0.0740180620770593 RSS(ph)YLLAITTER ddPTM_PC-9_Lapatinib_30min_R1 1 RSSYLLAITTER 12 1 Q9P227;Q9P227-2 Q9P227 ARHGAP23 Rho GTPase-activating protein 23 1 RS(0.202)S(0.795)Y(0.003)LLAITTER 62.203 0.024136 1912600.0 17035.0 13681.0 16509.0 13269.0 14431.0 13878.0 13439.0 11917.0 14990.0 12423.0 True False 16792.077776163595 13649.322485058141 15151.693746582894 14244.846524086415 13582.19695243762 13284.470291198095 14134.805662467983 12470.707325147381 13301.668348302115 14570.298997393023 1.152486834976283 0.9367908295842339 1.0399027329016306 0.9776632948050799 0.9321838182502501 0.9117500123762049 0.9701108855073626 0.8558992047712055 0.9129303626975742 1.0 13.830742862829029 -1.522878745302831 0.5858509520143989 0.9264173496187366 11.930748354223066 0.5580155973679959 0.05206764863869667 119.24305179371186 0.9703247933883564 0.023669891776531154 1672.3468783039953 0.02999999999844621 1.522878745302831 11.00433100460433 RSSDGS(ph)LSHEEDLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSDGSLSHEEDLAK 15 1 A0A2R8Y7R9;Q13136-2;Q13136;E9PJZ7;H0YEF9 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 RS(0.034)S(0.194)DGS(0.701)LS(0.072)HEEDLAK 78.191 0.0055698 10932000.0 10105.0 14753.0 16282.0 18094.0 24516.0 24969.0 20609.0 24025.0 21898.0 15704.0 True False 11815.576917152519 16217.580340819657 16670.224629828852 17080.251841539477 19712.26578957855 23659.581684587647 18656.766323761014 23394.369206591655 22218.216823054114 18551.0108872044 0.6369236150522848 0.8742154505448416 0.8986154302419808 0.9207181185646663 1.0625979311550686 1.2753796452627222 1.005700791035035 1.2610832557231677 1.1976822696157856 1.0 14.179210184304969 -5.40488546187115 0.6668041000317154 1.1662244214175201 0.5849321685314527 0.7083351569492992 0.10095969583586532 0.8877541931665303 0.509964115717304 0.05080108950092358 0.3494639397407313 3.936538815959637e-06 5.40488546187115 -0.5812922528860675 RSSDPALIGLST(ph)SVSDSNFSSEEPSRK ddPTM_PC-9_AZD4547_30min_R2 1 RSSDPALIGLSTSVSDSNFSSEEPSRK 27 2 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 RS(0.128)S(0.128)DPALIGLS(0.103)T(0.507)S(0.126)VS(0.008)DSNFSSEEPSRK 57.431999999999995 0.026344 5362900.0 13015.0 12300.0 13489.0 20577.0 19100.0 16140.0 14104.0 17771.0 11553.0 14308.0 True False 17153.499271182714 16275.734460390348 13310.127046443971 15833.290561480899 16448.29468999856 15130.763248540745 15359.228676931609 15024.900286954635 12163.667994083036 13807.081275016253 1.2423696891117577 1.178796165257685 0.9640072931654633 1.1467514564523529 1.1912941165749167 1.0958697893608897 1.1124167643399006 1.0882024946244078 0.8809731580339899 1.0 13.75312075525699 -8.118837604242005 4.5950563780346725 0.9428619841643738 1.1280342923367872 0.5071187505326161 0.0745597767071993 0.19295984403690278 6.218455097759634 0.05555152342628311 0.019753878547149974 7.606106389465302e-09 8.118837604242005 0.18517230817241337 RSSIT(ph)EPEGPNGPNIQK ddPTM_PC-9_AZD4547_30min_R2 1 RSSITEPEGPNGPNIQK 17 1 Q13625-2;Q13625;Q13625-3 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 RS(0.009)S(0.052)IT(0.939)EPEGPNGPNIQK 116.24 0.00048571 18738000.0 13785.0 8809.5 15407.0 24438.0 23452.0 17092.0 14617.0 20204.0 15548.0 20519.0 True False 18168.343254187766 11656.998595838108 15202.693113245037 18804.196663336246 20196.094610986718 16023.234538045755 15917.884683118917 17081.93604173268 16369.8355381289 19800.63605549753 0.9175636178184 0.5887183908216732 0.7677881190601501 0.9496763947699232 1.0199720127363985 0.8092282739370384 0.8039077451100067 0.8626963292419074 0.8267328126352745 1.0 14.273259154267127 -8.143007663301118 0.02546929344079849 1.7608541593028995 6.8386184211621525e-06 0.15620396477200882 0.11068562253391476 316.1836077355844 7.64069952488339 265.84946689814524 259.67666532536407 7.194362831486075e-09 8.143007663301118 -1.7608473206844784 RSSIT(ph)EPEGPNGPNIQK ddPTM_PC-9_Lapatinib_30min_R1 3 RSSITEPEGPNGPNIQK 17 1 Q13625-2;Q13625;Q13625-3 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 RS(0.005)S(0.362)IT(0.633)EPEGPNGPNIQK;RS(0.313)S(0.313)IT(0.374)EPEGPNGPNIQK;RS(0.115)S(0.349)IT(0.536)EPEGPNGPNIQK 87.429 0.0098776 126525000.0 89925.0 67756.0 65043.0 67117.0 80117.0 66557.0 61831.0 53619.0 78337.0 48545.0 True False 88642.65300977469 67599.11514491608 59695.415613240766 72053.00807574851 75404.67557608239 63710.51226194496 65032.30663859347 56110.334485783154 69513.86213481937 56935.93856785345 1.5568840215768944 1.1872837586466547 1.0484663485804964 1.2655101485659936 1.3243774928943834 1.1189858965092478 1.1422013630475445 0.9854994208783195 1.220913607175829 1.0 15.797051964006561 -4.766765640143997 4.603945117727329 1.146547048409077 1.5874774159209653 0.5869726419504435 0.10449246673978511 0.14058409382084136 6.8259645594206715 0.026727734130689764 0.2034167927227328 1.7109383456850625e-05 4.766765640143997 0.4409303675118883 RSSMGS(ph)TAVATDVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSMGSTAVATDVK 14 1 Q6UXY1;B0QYF0;Q6UXY1-2 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 RS(0.002)S(0.051)MGS(0.771)T(0.175)AVAT(0.002)DVK 112.83 0.00025637 8851300.0 49740.0 51164.0 51110.0 56308.0 58032.0 47001.0 52201.0 60867.0 43842.0 35070.0 True False 58159.99959021932 56243.22378890375 52328.65623575439 53153.24531299906 46661.046186197666 44536.184819468275 47256.14337748798 59269.30574391736 44483.1063090848 41427.913386032764 1.403884358072152 1.357616621064625 1.2631255585611212 1.2830297489933307 1.1263190050486402 1.0750284332322528 1.1406836481757292 1.430661138822882 1.073747207458488 1.0 15.338315536978973 -5.5703725720368595 1.2030992263231288 1.1622253368067148 1.402318027520138 0.4113039666388326 0.11082285918829622 0.6539848020158351 1.714253981407194 0.03878858366827759 0.13884877321376743 2.689226783372865e-06 5.5703725720368595 0.2400926907134231 RSSMS(ph)MEETEHTC ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSMSMEETEHTC 13 1 O75030-11;O75030-10;O75030-9;O75030-12;O75030-4;O75030-3;O75030-8;O75030-7;O75030-6;O75030-2;O75030-5;O75030 O75030-11 MITF Microphthalmia-associated transcription factor 1 RSSMS(0.982)MEET(0.017)EHTC 72.243 0.014621 1629100.0 3453.4 3663.9 3483.2 3206.1 4663.1 3641.1 4646.7 5429.3 4243.0 2502.7 True False 4037.992412240923 4027.627778128462 3566.2526981095593 3026.4726113164434 3749.3990293434354 3450.154306209782 4206.530936805294 5286.786627818856 4305.045848032631 2956.4196986377005 1.3658386913406118 1.3623328852748369 1.206274163222788 1.0236951853321175 1.2682228545125493 1.167004234141584 1.4228463363113284 1.7882395487538436 1.456168706363433 1.0 11.529635376257962 -7.387372031087447 5.255285309764794 1.4909580171049661 1.2300542746429368 0.13207257612136591 0.2040105943529074 0.3200225453405407 12.356357894188719 0.08596172656256383 0.05692576625662382 4.098528589835321e-08 7.387372031087447 -0.2609037424620293 RSSMSMEET(ph)EHTC ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSMSMEETEHTC 13 1 O75030-11;O75030-10;O75030-9;O75030-12;O75030-4;O75030-3;O75030-8;O75030-7;O75030-6;O75030-2;O75030-5;O75030 O75030-11 MITF Microphthalmia-associated transcription factor 1 RS(0.028)S(0.028)MS(0.149)MEET(0.781)EHT(0.015)C 50.806000000000004 0.045316 0.0 2078.4 2100.4 4428.2 2365.9 3481.0 4700.0 3204.3 3038.0 3469.2 2162.2 True False 2430.232069728828 2308.913830939988 4533.785082042016 2233.3462933512906 2798.923038567586 4453.523726122872 2900.76550687697 2958.255719027075 3519.930486918407 2554.1897440342177 0.9514688857415875 0.903971146361731 1.7750384804541282 0.8743854283213233 1.0958164110967041 1.7436150687414278 1.1356891216293714 1.1581973210630212 1.3781006266820448 1.0 11.318649987701603 RSSPS(ph)ARPPDVPGQQPQAAK ddPTM_PC-9_AZD4547_30min_R2 1 RSSPSARPPDVPGQQPQAAK 20 2 A0A0A6YYC7;Q96JP5-2;Q96JP5 A0A0A6YYC7 ZFP91-CNTF;ZFP91 E3 ubiquitin-protein ligase ZFP91 1 RS(0.208)S(0.208)PS(0.585)ARPPDVPGQQPQAAK 52.784 0.010874 96417000.0 16550.0 17706.0 25137.0 33123.0 24626.0 25487.0 19784.0 30921.0 23607.0 25518.0 True False 21812.555738614985 23429.118240298478 24803.66695577598 25487.004095248663 21207.104975701805 23893.293860939157 21544.737673313586 26142.869943893114 24854.817825354316 24624.62258707471 0.885802641704821 0.9514508560466731 1.0072709487452307 1.0350211056077916 0.8612154318593805 0.9703009163470622 0.8749266144944802 1.0616556599578229 1.0093481732548637 1.0 14.587813992608686 -7.77777241124319 24.999705357710255 1.0266264385482289 0.9455086349285573 0.3190088214795561 0.055103155125472564 319.5826388330788 489153.36878250446 0.03053875203250756 0.014739646767567921 1.6681211498831818e-08 7.77777241124319 -0.08111780361967158 RSSQGAT(ph)QMPLY(ph)SSPIVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSQGATQMPLYSSPIVK 18 1 M0R201;M0QY29;Q05469-2;Q05469 M0R201 LIPE Hormone-sensitive lipase 2 RS(0.002)S(0.031)QGAT(0.959)QMPLY(0.682)S(0.264)S(0.063)PIVK 54.343 0.035088999999999995 0.0 4527.6 3705.4 4248.5 6517.0 5936.3 4482.0 6693.9 3768.2 5774.1 3232.1 True False 5294.033255823827 4073.2476238645168 4349.800352525972 6151.873618399074 4773.12462908611 4246.956029889937 6059.8053323608065 3669.288742737927 5858.535288976011 3818.0541447104797 1.3865788842094249 1.0668386223667312 1.1392715209531985 1.6112588730366384 1.2501458722629122 1.1123352024155175 1.5871449441742573 0.961036329938209 1.5344295986719851 1.0 11.898621846741658 -10.215558435189626 5.856722985630477 0.9999999937267343 1.284563262038401 0.13962676282666142 0.21798085139730722 1.688161919532179e-08 4.0614725234660726e-09 0.1995391379200221 0.04839534809235015 6.087536312341539e-11 10.215558435189626 0.2845632683116668 RSSQPS(ph)PTAVPAS(ph)DSPPTKQEVK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSQPSPTAVPASDSPPTKQEVK 23 2 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 2 RS(0.217)S(0.308)QPS(0.462)PT(0.014)AVPAS(0.556)DS(0.398)PPT(0.045)KQEVK 65.765 0.012117000000000001 17462000.0 99378.0 77922.0 81786.0 67858.0 81081.0 80564.0 65540.0 67015.0 73145.0 78416.0 True False 97960.85149630684 77741.57639651338 75061.87078308966 72848.50368765203 76311.97499137923 77118.46552385662 68933.3405103171 70128.7615502854 64906.639849003324 91970.10111724789 1.0651380210120858 0.8452918443288944 0.8161551403254107 0.7920889811220417 0.8297476469455337 0.8385166982206783 0.7495190249104714 0.7625169560364178 0.7057363106109585 1.0 16.48887730614775 -4.684334756535368 2.376089965979093 0.8019390583450549 1.1755219743263523 0.5042338663151247 0.07434960320098975 0.6406609789793205 3.4575489223425073 0.018441675177021583 0.5499945250802508 2.0685462874637412e-05 4.684334756535368 0.37358291598129745 RSSQPSPT(ph)AVPASDSPPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSQPSPTAVPASDSPPTK 19 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 RS(0.145)S(0.145)QPS(0.302)PT(0.409)AVPASDSPPTK 93.09299999999999 0.0007124 8168000.0 35363.0 39656.0 39219.0 37220.0 42280.0 33910.0 33300.0 35210.0 28792.0 26852.0 True False 41349.25744891289 43592.78560262624 40154.12969888576 35134.684068868126 33995.53750951954 32131.69990485671 30145.58292887777 34285.774808078764 29213.028530887474 31720.05503968495 1.3035682755651226 1.3742972875705077 1.2658909213319125 1.107648899880884 1.0717363972725689 1.0129774322477294 0.9503635126472083 1.080886359282285 0.9209639924753934 1.0 14.953107653914532 -5.861192888442547 1.3123984651607878 0.997605641416134 1.3539605869780236 0.9020915043793742 0.04605732285951318 0.12195398922472062 0.4240499490043703 0.015468731672003362 0.03379727393892211 1.3765979280693716e-06 5.861192888442547 0.3563549455618896 RSST(ph)S(ph)GDTEEEEEEEVVPFSSDEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSTSGDTEEEEEEEVVPFSSDEQK 25 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 2 RS(0.166)S(0.134)T(0.688)S(0.562)GDT(0.45)EEEEEEEVVPFSSDEQK 86.551 0.0001091 0.0 14500.0 15660.0 14920.0 15595.0 18383.0 19976.0 15455.0 17826.0 18051.0 13463.0 True False 16954.563611945734 17214.621306665485 15275.7493844151 14721.262709672177 14780.983113469663 18928.423394261798 13990.990515489679 17358.086388208238 18314.96172586308 15903.735326950644 1.0660743066576532 1.0824262950033756 0.9605133052314224 0.92564812020767 0.929403238270801 1.1901872739409518 0.8797298387995928 1.0914471368743817 1.1516138409840324 1.0 13.957078032151252 RSST(ph)SGDT(ph)EEEEEEEVVPFSSDEQKR ddPTM_PC-9_AZD4547_30min_R2 1 RSSTSGDTEEEEEEEVVPFSSDEQKR 26 2 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 2 RS(0.059)S(0.198)T(0.519)S(0.519)GDT(0.705)EEEEEEEVVPFSSDEQKR 67.895 0.001005 5108900.0 8735.4 7320.7 7344.4 12198.0 13013.0 9436.7 8051.3 10690.0 9249.1 9302.1 True False 11513.075492392587 9686.973110908915 7247.008457254292 9385.939557221353 11206.369570730434 8846.621657218371 8767.85010256519 9038.106131762148 9737.988543588119 8976.436310338884 1.2825886681925267 1.0791557780844108 0.8073369215472881 1.045619801970946 1.2484207744918945 0.9855382861714292 0.9767629156424305 1.0068701898271404 1.0848390393381495 1.0 13.131927086217534 RSST(ph)SGDT(ph)EEEEEEEVVPFSSDEQKR ddPTM_PC-9_Lapatinib_30min_R1 2 RSSTSGDTEEEEEEEVVPFSSDEQKR 26 2 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 2 RS(0.063)S(0.159)T(0.492)S(0.492)GDT(0.794)EEEEEEEVVPFSSDEQKR;RS(0.009)S(0.019)T(0.566)S(0.566)GDT(0.839)EEEEEEEVVPFSSDEQKR 73.153 0.00034988 10653200.0 18496.7 18215.4 20870.0 19695.6 21891.0 18343.1 15325.4 16938.7 23470.0 18621.4 True False 18232.933666120643 18173.223360450836 19154.149160529716 21144.08012659555 20603.414419361925 17558.60837285456 16118.874224241894 17725.73383976454 20826.56144994335 21840.084178544184 0.8348380673382557 0.832104089521061 0.8770181013929815 0.9681318054335892 0.9433761450243323 0.8039624861017812 0.7380408469339675 0.8116147215759542 0.9535934605235393 1.0 14.414690796417755 -6.771624833936521 24.99732085545575 0.8419556431644323 0.8913143728551954 0.004503610228782207 0.0813108406079758 620.0764911619658 1521792.638784572 0.02965413106226285 0.02644095091660805 1.6919018529786811e-07 6.771624833936521 0.04935872969076316 RSST(ph)SGDTEEEEEEEVVPFSSDEQK ddPTM_PC-9_AZD4547_30min_R2 2 RSSTSGDTEEEEEEEVVPFSSDEQK 25 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RS(0.094)S(0.094)T(0.374)S(0.374)GDT(0.063)EEEEEEEVVPFSSDEQK;RS(0.049)S(0.155)T(0.307)S(0.307)GDT(0.183)EEEEEEEVVPFSSDEQK 58.373000000000005 0.009412 2149800.0 11777.6 9918.099999999999 13846.3 18609.6 16634.8 13309.2 11243.3 17841.9 12955.3 13024.3 True False 15522.631810701618 13123.931865983533 13662.6890149883 14319.444235453888 14325.345157549113 12476.97362004203 12243.93191884183 15084.844321074559 13640.090709230844 12568.323221288383 1.2350598832793533 1.0442070620648944 1.087073333047822 1.1393281333821392 1.1397976408885366 0.9927317590709616 0.9741897708441254 1.2002272741938766 1.085275296399689 1.0 13.617504567757097 -6.727605038281107 24.99996722976389 1.0582304795468669 1.122611506030238 0.20978752883774543 0.07501193692008978 386.54675420734327 285615.7743973266 0.02566231887153678 0.02566083565958054 1.8723841741991116e-07 6.727605038281107 0.06438102648337107 RSST(ph)SGDTEEEEEEEVVPFSSDEQKR ddPTM_PC-9_AZD4547_30min_R2 1 RSSTSGDTEEEEEEEVVPFSSDEQKR 26 2 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RS(0.003)S(0.009)T(0.421)S(0.421)GDT(0.146)EEEEEEEVVPFSSDEQKR 84.025 1.2445999999999999e-05 24776000.0 31913.0 26266.0 34636.0 45779.0 43140.0 38320.0 33533.0 43257.0 34227.0 38699.0 True False 42060.670168363766 34755.97084037502 34176.704009239635 35225.35882849947 37150.7556506041 35923.84434226032 36517.37203797131 36572.62459697243 36036.16934419462 37344.15978905883 1.1262984736019361 0.9306936087649746 0.9151820312008411 0.9432628562932581 0.9948210338765904 0.9619668656405376 0.9778603199065747 0.9793398701043358 0.9649746987948721 1.0 15.188595018757626 -10.89911722048572 2.4502811194896807 1.0007939290912815 0.9731272292881893 0.010590978016802977 0.05498564114951505 8230599.936810024 8155223.35878056 46281.76655321784 0.014080387703003377 1.2614870004992202e-11 10.89911722048572 -0.02766669980309222 RSST(ph)SGDTEEEEEEEVVPFSSDEQKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSTSGDTEEEEEEEVVPFSSDEQKR 26 2 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RS(0.004)S(0.01)T(0.445)S(0.445)GDT(0.097)EEEEEEEVVPFSSDEQKR 98.76 2.6345000000000002e-08 16436000.0 12620.0 12968.0 12038.0 18343.0 17410.0 15035.0 13336.0 15150.0 13960.0 10520.0 True False 14756.31674363828 14255.377337473687 12325.031574369228 17315.301178808386 13998.63547873073 14246.53813239518 12072.717535721149 14752.32855275186 14164.1385902747 12427.192723725813 1.1874215739380733 1.1471116328837108 0.9917792254753126 1.3933397158756755 1.1264519501660855 1.1464003535726859 0.9714758436691896 1.1871006494159322 1.139769769823617 1.0 13.601212811018462 -7.019613172231898 23.73998424461146 1.0857154010850778 1.1671697930707512 0.14319429623581004 0.10862032137442865 953.0037829929821 1153523.1746109978 0.04110164312776998 0.03235460113099035 9.558435805325907e-08 7.019613172231898 0.08145439198567339 RSST(ph)SGDTEEEEEEEVVPFSSDEQKR ddPTM_PC-9_Lapatinib_30min_R1 1 RSSTSGDTEEEEEEEVVPFSSDEQKR 26 2 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RS(0.017)S(0.041)T(0.446)S(0.446)GDT(0.049)EEEEEEEVVPFSSDEQKR 60.941 0.017476 19355000.0 8181.6 6623.3 6851.8 5229.1 5845.7 6134.2 5627.8 5806.2 6324.2 4800.9 True False 8064.9288836783135 6607.964155784336 6288.471452712867 5613.66545776624 5501.86741908839 5871.854565518616 5919.179946963114 6075.977248575202 5611.901999221633 5630.729168202857 1.4323063039901762 1.1735538965539307 1.1168129854698623 0.9969695380603676 0.977114553858822 1.0428231211469754 1.0512279618045137 1.0790746752457379 0.996656353303664 1.0 12.459106045197336 -4.492498773272255 1.1557544199474032 1.025456273289964 1.8683597570204185 0.9272075405845225 0.03484724861893381 0.7191731902119609 0.5221035253024283 0.011373102769190456 0.8602924416912864 3.217371620615482e-05 4.492498773272255 0.8429034837304545 RSST(ph)SSEPTPTVK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSTSSEPTPTVK 13 1 Q69YQ0-2;Q69YQ0;F8WAN1;A0A494C1J1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 RS(0.001)S(0.121)T(0.875)S(0.002)SEPTPTVK 190.34 5.9248e-05 62790000.0 41331.0 41909.0 53856.0 40475.0 33067.0 35162.0 40765.0 31857.0 37138.0 32207.0 True False 40741.61236082285 41811.96228538126 49428.16757017194 43451.66652064189 31122.064072223326 33658.2032266254 42875.61223532312 33337.19251969626 32955.12735952262 37773.93703687005 1.0785640988667966 1.1068997717809985 1.3085257044275405 1.1503081206025725 0.8239031065744081 0.8910430277302736 1.1350580743932905 0.8825448215036943 0.8724303036603274 1.0 15.205103537898841 -6.1830198054466345 7.63490510033635 0.9364215443200932 1.169156164398729 0.5600175508380616 0.09846522098312781 0.23285046818588515 20.25916421635905 0.030413757435804684 0.039341214205428354 6.561153443161284e-07 6.1830198054466345 0.23273462007863577 RSSTS(ph)GDT(ph)EEEEEEEVVPFSSDEQKR ddPTM_PC-9_AZD4547_30min_R2 1 RSSTSGDTEEEEEEEVVPFSSDEQKR 26 2 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 2 RS(0.05)S(0.12)T(0.116)S(0.8)GDT(0.913)EEEEEEEVVPFS(0.001)S(0.001)DEQKR 59.211999999999996 0.018992 4217800.0 5877.5 5792.9 6563.5 9313.7 8818.5 7478.8 6633.4 7558.7 6854.6 5688.8 True False 7746.422740405413 7665.341638666273 6476.4637014852815 7166.570360230574 7594.203493390173 7011.149453729025 7223.759749401459 6390.676596646449 7216.9201620567455 5489.636843535958 1.4110993060546104 1.3963294580573586 1.179761774061851 1.305472577602142 1.383370833051068 1.2771608857851218 1.3158902774975778 1.1641346738940417 1.3146443686078546 1.0 12.422494998308052 -14.197852476777445 0.15703149454308182 2.5684743340238155e-10 1.3894763646783566 0.6354910192132637 0.07298860089438332 78.7289263421589 0.7850752831371494 24.69457508146092 0.3354357963929503 6.340850637198916e-15 14.197852476777445 1.3894763644215091 RSSTS(ph)GDTEEEEEEEVVPFSSDEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSTSGDTEEEEEEEVVPFSSDEQK 25 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RS(0.259)S(0.259)T(0.092)S(0.328)GDT(0.064)EEEEEEEVVPFSSDEQK 94.838 1.266e-06 34440000.0 45118.0 45240.0 39824.0 54293.0 54566.0 54079.0 55333.0 53199.0 52410.0 46266.0 True False 52755.58627888047 49731.12821925587 40773.555193361026 51251.13923028095 43874.184005308496 51243.00203936139 50091.457663771595 51802.58261899976 53176.39710002127 54653.659558545485 0.9652708840543097 0.9099322647549968 0.746035224771802 0.9377439615984045 0.802767543101301 0.9375950751197077 0.916525225728264 0.9478337413711222 0.9729704749790495 1.0 15.738030480207874 -7.709356672943647 0.9974277009822918 0.992433419650098 0.873365968837125 0.3225444812884666 0.06179881647294421 0.6566973167528162 1.1854103181568412 0.05358631066969707 0.022449553581133624 1.95273507470037e-08 7.709356672943647 -0.11906745081297299 RSSTS(ph)GDTEEEEEEEVVPFSSDEQK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSTSGDTEEEEEEEVVPFSSDEQK 25 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RS(0.156)S(0.156)T(0.156)S(0.438)GDT(0.095)EEEEEEEVVPFSSDEQK 107.85 2.159e-07 21953000.0 63126.0 53110.0 64771.0 51705.0 48299.0 58122.0 57505.0 52146.0 57574.0 48720.0 True False 62225.81166410942 52987.02705806866 59445.77840329039 55507.558182823734 45458.1477794875 55636.25754899949 60482.32752587404 54568.89352833224 51089.40983890235 57141.18708468063 1.088983530774284 0.9273000748049618 1.0403315268056028 0.9714106586648974 0.7955408366319132 0.973662963398872 1.0584716666148708 0.9549835471122369 0.8940908028947697 1.0 15.802243387531687 -4.753265528305828 24.908242123915816 0.9575555441978602 1.0889837846884756 0.23609170116520684 0.07105450385329416 469.76324348903046 1431396.1992535454 0.018420123596407077 0.20188707326740973 1.7649583924960376e-05 4.753265528305828 0.1314282404906154 RSSTS(ph)SEPTPTVK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSTSSEPTPTVK 13 1 Q69YQ0-2;Q69YQ0;F8WAN1;A0A494C1J1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 RS(0.196)S(0.196)T(0.196)S(0.311)S(0.102)EPTPTVK 64.476 0.019239 3240700.0 22798.0 20171.0 24596.0 21950.0 20223.0 19624.0 17032.0 17429.0 20452.0 16899.0 True False 22472.896339358842 20124.29528880255 22573.811823305638 23564.27622305349 19033.52289994776 18784.727265778296 17913.833621783968 18238.814967692677 18148.48039089227 19819.96963349791 1.1338511993165317 1.0153544965472752 1.138942805702055 1.1889158590448743 0.9603204874632618 0.9477677117138494 0.9038275009012948 0.9202241630515463 0.9156664074913293 1.0 14.274667131698697 -6.382032808041275 5.633663818281491 0.9330251345374787 1.1126088218006578 0.7703800375094537 0.04758570883317338 0.11272024210348813 4.7530316794394345 0.015391598005636704 0.01746349087379223 4.149226968178226e-07 6.382032808041275 0.17958368726317908 RSSTSGDT(ph)EEEEEEEVVPFSSDEQK ddPTM_PC-9_Lapatinib_30min_R1 1 RSSTSGDTEEEEEEEVVPFSSDEQK 25 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RS(0.095)S(0.068)T(0.068)S(0.068)GDT(0.7)EEEEEEEVVPFSSDEQK 96.181 2.093e-06 25531000.0 16648.0 15310.0 17014.0 16683.0 15953.0 16482.0 15128.0 14906.0 14337.0 15548.0 True False 16410.59646713071 15274.550635643594 15615.174595939274 17909.92347285655 15014.67590480474 15777.103281418567 15911.25381812751 15598.587177028348 12722.216084696973 18235.45108359226 0.8999281888834928 0.8376294376061364 0.8563086552868091 0.9821486395239979 0.8233783653596877 0.8651885390219032 0.8725451180335212 0.8553990304667327 0.6976639089637909 1.0 14.15445826707719 RSSTSGDT(ph)EEEEEEEVVPFSSDEQKR ddPTM_PC-9_Lapatinib_30min_R1 2 RSSTSGDTEEEEEEEVVPFSSDEQKR 26 2 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 RS(0.183)S(0.183)T(0.183)S(0.183)GDT(0.268)EEEEEEEVVPFSSDEQKR;RS(0.007)S(0.096)T(0.096)S(0.021)GDT(0.781)EEEEEEEVVPFSSDEQKR 108.99 4.5022000000000004e-09 45654000.0 45810.2 32563.4 41344.9 42016.1 42154.5 45666.0 37214.8 37526.4 46469.4 35178.4 True False 45156.938147438195 32488.00144798935 37945.68191792933 45106.104155600806 39675.05518893576 43712.97163264531 39141.600250585114 39270.013540858505 41235.526827524394 41258.939567728456 1.0944764606300894 0.7874172673453905 0.9196960056532655 1.093244388444765 0.9616111224528038 1.0594787963682015 0.9486816835496309 0.9517940585068834 0.9994325413971042 1.0 15.332419121277008 -5.604594633952274 24.99999999988436 0.9991249807656278 0.9190752620331608 0.1192607375972633 0.08172720223067378 47.418311423151145 14502.584597931967 0.02120159516181405 0.03672224611314052 2.4854519184644803e-06 5.604594633952274 -0.08004971873246702 RSSWECT(ph)GSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSSWECTGSGR 11 1 Q8NEV8-2;Q8NEV8;E9PPH6 Q8NEV8-2 EXPH5 Exophilin-5 1 RS(0.001)S(0.107)WECT(0.839)GS(0.052)GR 101.72 0.012332 11504000.0 32992.0 21095.0 29707.0 35483.0 35047.0 36448.0 31763.0 33894.0 38169.0 28713.0 True False 38576.8939782975 23189.17218800181 30415.327544424876 33495.00254743812 28179.791936994592 34536.60271696303 28754.178695794144 33004.31841366151 38727.14941634634 33918.439608017055 1.137342826619281 0.6836744984731182 0.8967195394577003 0.987516021801933 0.8308103869947466 1.0182249866470823 0.8477447379093974 0.9730494325529208 1.1417727308184509 1.0 15.049782180890523 -8.02739528524437 6.4562418524680005 1.0681454099473615 0.9085141868430522 0.21305426264487315 0.11880826399290689 0.2630626110140953 38.38108037720831 0.07265749586859079 0.028837207419569976 9.38868384291277e-09 8.02739528524437 -0.15963122310430933 RST(ph)QGVTLTDLK ddPTM_PC-9_AZD4547_30min_R2 1 RSTQGVTLTDLK 12 1 Q9BZL4-3;K7EL81;K7ER83;Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-3;Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 RS(0.071)T(0.929)QGVTLTDLK 134.88 4.9851999999999996e-05 6045600.0 33823.0 22326.0 56213.0 43106.0 43309.0 38075.0 56461.0 36592.0 37849.0 36164.0 True False 44578.01043789573 29542.442891274386 55467.578891078294 33168.57768106114 37296.29291775643 35694.164230990646 61485.91962054991 30937.54720050891 39849.62086973508 34897.909367464905 1.277383409089128 0.8465390456545977 1.5894241201391381 0.9504459803538832 1.0687257086101416 1.0228166924024418 1.761879743944571 0.8865157759092522 1.141891350858015 1.0 15.090852990897467 RST(ph)QGVTLTDLK ddPTM_PC-9_Lapatinib_30min_R1 1 RSTQGVTLTDLK 12 1 Q9BZL4-3;K7EL81;K7ER83;Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-3;Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 RS(0.022)T(0.978)QGVTLTDLK 196.02 1.1179000000000001e-05 6066400.0 46689.0 67236.0 47518.0 37374.0 57003.0 49959.0 69417.0 45737.0 42383.0 26555.0 True False 46023.20629828602 67080.31917296766 43611.25346478441 40122.608636009136 53650.19561220996 47822.370030117134 73011.07260001048 47862.10799112746 37609.380227224065 31144.996367686665 1.477707871754183 2.1538072562616946 1.4002651645845638 1.2882521533262037 1.7225943769212548 1.5354752161645284 2.34423121255395 1.5367511180956506 1.2075577015075296 1.0 14.92671278371818 -8.28907332536262 3.1578158705711745 1.039871746272034 1.6996626655529496 0.3664952507420136 0.3122146968247268 0.2731784008490425 5.204015581964301 0.2925492429162695 0.08244984721505938 5.139568688648257e-09 8.28907332536262 0.6597909192809157 RST(ph)QGVTLTDLQEAEK ddPTM_PC-9_AZD4547_30min_R2 2 RSTQGVTLTDLQEAEK 16 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 RS(0.002)T(0.998)QGVTLTDLQEAEK;RS(0.048)T(0.952)QGVTLTDLQEAEK 132.5 2.1728000000000003e-05 10510900.0 50614.0 36450.0 70222.0 74440.0 68900.0 54383.0 70746.0 48468.0 56223.0 57565.0 True False 66708.19916339939 48231.749681400644 69290.81039776021 57279.00808653529 59334.424300570696 50982.42241297343 77042.25694683797 40978.3842838398 59194.83299847062 55549.66687142232 1.200874873251807 0.8682635269989999 1.2473668034435517 1.0311314416901145 1.0681328555562493 0.9177808848247383 1.3869076321405012 0.7376891094358883 1.065619945759271 1.0 15.761490639419657 -7.790227033302846 24.999911736933583 0.9262412531759153 1.0882330791456656 0.17726222994360485 0.16393365325439768 377.409515543429 327746.49501497176 0.08313957331439079 0.03995002093372722 1.6209624958050135e-08 7.790227033302846 0.16199182596975026 RST(ph)QGVTLTDLQEAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RSTQGVTLTDLQEAEK 16 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 RS(0.002)T(0.998)QGVTLTDLQEAEK;RS(0.002)T(0.998)QGVTLTDLQEAEK;RS(0.053)T(0.947)QGVTLTDLQEAEK;RS(0.239)T(0.756)QGVT(0.005)LTDLQEAEK;RS(0.241)T(0.759)QGVTLTDLQEAEK 218.05 1.188e-21 48082400.0 277632.0 289716.0 228638.0 340966.0 241162.0 289175.0 304669.0 244545.0 223111.0 204578.0 True False 324629.61411805 318477.08981365967 234089.59703444413 321862.78044668667 193908.03729590238 274010.1539365065 275808.5467074549 238125.95286684565 226373.57629045637 241666.3719614427 1.3432965930809933 1.317837840775265 0.9686477896552053 1.3318476122033194 0.8023790638394652 1.1338365024167456 1.1412781367506917 0.9853499720881236 0.9367193890202222 1.0 17.88265720951899 -1.52287889744261 0.422056560045722 1.002663069498565 8.165446544303244 0.4036171090874281 0.13787241498863348 78.1217793715443 0.997150388850803 0.08987692695667115 473.13810914143806 0.02999998948900444 1.52287889744261 7.162783474804678 RST(ph)QGVTLTDLQEAEK ddPTM_PC-9_Lapatinib_30min_R1 1 RSTQGVTLTDLQEAEK 16 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 RS(0.007)T(0.993)QGVTLTDLQEAEK 192.46 4.5252e-09 27823000.0 146880.0 162070.0 120310.0 92909.0 108510.0 111720.0 137720.0 92303.0 107950.0 66567.0 True False 144785.4642655071 161694.7368725509 110418.57621003002 99741.8377953382 102127.6551388681 106941.99603203997 144850.4677308645 96591.73434866838 95791.534236105 78073.01725504808 1.85448788014076 2.071070679186489 1.4142988204146871 1.2775455759510697 1.308104371132969 1.3697689648996532 1.8553204784909052 1.237197405002596 1.2269480238374069 1.0 16.25253640552912 -5.3019555811096755 6.679117640058399 1.3595960439090555 1.9626997874041738 0.5849026002467256 0.2104965126790195 0.13756603248342772 17.940386835949173 0.055749481616925764 0.11992335494756047 4.989355151141342e-06 5.3019555811096755 0.6031037434951183 RST(ph)SPIIGSPPVR ddPTM_PC-9_AZD4547_30min_R2 1 RSTSPIIGSPPVR 13 1 Q86TB9-4;Q86TB9;Q86TB9-2 Q86TB9-4 PATL1 Protein PAT1 homolog 1 1 RS(0.188)T(0.607)S(0.205)PIIGSPPVR 64.313 0.035947 62278000.0 18129.0 20836.0 28129.0 43317.0 35867.0 19491.0 23018.0 27938.0 23587.0 29927.0 True False 23893.644893374676 27570.82952981245 27755.991080837895 33330.934890978664 30887.48615948577 18272.224688804676 25066.557408225442 23620.82405137239 24833.76066618512 28879.264839069874 0.8273633358232061 0.9546929149149502 0.9611044891727183 1.1541476237956814 1.0695385194743265 0.6327108667975766 0.8679776839164431 0.8179163902890111 0.8599166496990701 1.0 14.817746396479253 -6.730488401983137 24.999998133768223 0.8263408680696843 0.9983603288204346 0.3173777987109083 0.11508822677040129 236.02724012482054 190645.4394505931 0.03875632700540345 0.03875235881132088 1.8599942344879283e-07 6.730488401983137 0.17201946075075025 RST(ph)STLYSQFQTAESENR ddPTM_PC-9_Lapatinib_30min_R1 1 RSTSTLYSQFQTAESENR 18 1 O95248;O95248-5;O95248-4;H0Y5W8 O95248 SBF1 Myotubularin-related protein 5 1 RS(0.076)T(0.263)S(0.263)T(0.263)LY(0.134)S(0.001)QFQTAESENR 79.514 0.019506 0.0 12288.0 11177.0 13086.0 10603.0 11756.0 8947.0 9835.2 9735.3 11280.0 10037.0 True False 12112.770866656783 11151.120343212835 12010.119593420783 11382.77999057112 11064.53519318527 8564.357666475667 10344.418531996806 10187.637578459959 10009.527616334082 11771.882076538166 1.028957883531472 0.9472674183032691 1.020237844325457 0.9669464845606514 0.9399121670813653 0.7275266275003532 0.878739564730575 0.8654213075039487 0.8502911897396146 1.0 13.523057374982724 -6.5339390685547905 24.92486428748242 0.8543075228359052 0.985287066315084 0.45070933909754496 0.06553383314801206 177.73724319438827 400534.73886656173 0.020567287229931706 0.020584520414696907 2.924562664727498e-07 6.5339390685547905 0.13097954347917884 RST(ph)VLGLPQHVQK ddPTM_PC-9_AZD4547_30min_R2 1 RSTVLGLPQHVQK 13 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 RS(0.143)T(0.857)VLGLPQHVQK 85.163 0.021624 53509000.0 70071.0 62674.0 100650.0 108310.0 104740.0 76411.0 84143.0 116990.0 83085.0 99980.0 True False 92352.12043265808 82932.14484313049 99315.31523645816 83340.80287281888 90198.65894400269 71633.00809072152 91631.5639934102 98911.88366275546 87476.70347861065 96479.7306315435 0.9572178511292825 0.8595810156212884 1.0293904697531109 0.86381670354261 0.9348974997501989 0.7424669163338389 0.9497493763052834 1.0252089533759206 0.9066847814147052 1.0 16.55793825883265 -7.511630762290376 24.98054920878211 0.9770639693100766 0.8975838920515041 0.18853866583912482 0.07534217756090143 915.0338941176612 2032204.8403146293 0.032792890986526504 0.02060124043881088 3.078713228166641e-08 7.511630762290376 -0.07948007725857242 RST(ph)VLGLPQHVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSTVLGLPQHVQK 13 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 RS(0.241)T(0.759)VLGLPQHVQK;RS(0.217)T(0.783)VLGLPQHVQK 112.12 0.00041630000000000004 26804100.0 99090.0 94078.0 105522.0 106171.0 149820.0 95390.0 86332.0 106518.0 89760.0 81148.0 True False 115863.97988329006 103417.44210015786 108038.0446744134 100222.58308102643 120463.84649186897 90387.58047550221 78154.00797044669 103722.01536515001 91072.57019076351 95859.49003278548 1.2086855442654945 1.0788440671318764 1.1270458943341202 1.0455155044821196 1.2566710552149651 0.9429173934118386 0.8152975562848995 1.0820213557330152 0.950063161817523 1.0 16.548633644468474 -6.786888431874757 24.998381120688627 0.9542634908418683 1.133427323540321 0.5510381155290752 0.08335058357878453 180.19477380463 177002.43672403917 0.029016294955525407 0.025599254106335175 1.6334715248324456e-07 6.786888431874757 0.1791638326984526 RST(ph)VLGLPQHVQK ddPTM_PC-9_Lapatinib_30min_R1 1 RSTVLGLPQHVQK 13 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 RS(0.379)T(0.621)VLGLPQHVQK 62.298 0.042449 23059000.0 105030.0 92365.0 96741.0 83245.0 73665.0 67871.0 63594.0 50532.0 99657.0 54028.0 True False 103532.25293985718 92151.1345173889 88787.32841105924 89367.11499717945 69332.16953096224 64968.315545028534 66886.58615216821 52879.90119613554 88432.5792252664 63366.66781221525 1.6338598274832936 1.4542524910805683 1.4011677034079992 1.410317412650063 1.0941425819711008 1.0252758711813552 1.0555484209834751 0.834506579276713 1.39556934707902 1.0 15.951436531783298 -6.167312999595209 1.8111259345831558 1.0454410989141032 1.5052460815572333 0.6687810042887469 0.14129286465965887 0.20530403557081767 1.3303833968196879 0.04685221587716931 0.06665006662509748 6.802788993934819e-07 6.167312999595209 0.4598049826431301 RSTS(ph)LSSPR ddPTM_PC-9_AZD4547_30min_R2 1 RSTSLSSPR 9 1 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 RS(0.001)T(0.105)S(0.656)LS(0.204)S(0.034)PR 63.693999999999996 0.025863999999999998 20734000.0 13587.0 7671.5 23001.0 35338.0 26735.0 15721.0 19487.0 22308.0 18204.0 16954.0 True False 17907.383372843608 10151.162350641012 22695.99171141359 27191.370066657513 23023.30672969172 14737.963384777511 21221.30524867884 18860.81118684284 19166.226275797424 16360.445620395976 1.0945535218502314 0.6204697956384467 1.387247770508116 1.6620189142500503 1.4072542560203494 0.9008289704776883 1.2971104663691437 1.1528299182346078 1.1714978137211363 1.0 13.997924424013698 -5.271357196555214 24.974595915177286 1.262728820703029 0.8575116483688174 0.31290399845994354 0.23017033290305494 710.8123579387693 1789937.8269437335 0.06285226540432164 0.1333654588691701 5.353561590836232e-06 5.271357196555214 -0.4052171723342115 RSTS(ph)PIIGSPPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSTSPIIGSPPVR 13 1 Q86TB9-4;Q86TB9;Q86TB9-2 Q86TB9-4 PATL1 Protein PAT1 homolog 1 1 RS(0.176)T(0.176)S(0.649)PIIGSPPVR 58.246 0.030331 8435000.0 17045.0 14862.0 20728.0 16929.0 20605.0 21179.0 14922.0 18717.0 12910.0 10673.0 True False 19930.38184590448 16337.401140463766 21222.234131377743 15980.523014558526 16567.59816423013 20068.335956501316 13508.480134075498 18225.69858230077 13098.784326679535 12607.930412578495 1.5807813966057926 1.2958035621900728 1.6832448654860164 1.267497717041277 1.3140616756340289 1.591723248764114 1.0714272439669048 1.4455741732297018 1.0389321560350089 1.0 13.622043856757696 -8.05944387958371 0.4646311117200496 0.9768923613335534 1.48416319292925 0.44860053659135535 0.17180791027450507 0.882315906319958 0.4988328389688014 0.18224421655685932 0.11621407190466272 8.720795859041155e-09 8.05944387958371 0.5072708315956966 RSTS(ph)TLYSQFQTAESENR ddPTM_PC-9_Lapatinib_30min_R1 1 RSTSTLYSQFQTAESENR 18 1 O95248;O95248-5;O95248-4;H0Y5W8 O95248 SBF1 Myotubularin-related protein 5 1 RS(0.105)T(0.121)S(0.374)T(0.374)LY(0.026)SQFQTAESENR 75.868 0.027257 0.0 3731.7 5494.4 6898.0 4650.1 5317.9 4258.9 5121.7 5543.0 5878.5 5744.5 True False 3678.4852736900325 5481.678054374927 6330.873067050023 4992.083866278864 5005.111577393664 4076.756774980798 5386.876565329431 5800.548015716368 5216.4014266507 6737.4291709348945 0.5459775799289925 0.8136156856420477 0.9396570867655656 0.7409478808051285 0.7428815131720559 0.6050908546197157 0.7995448157834869 0.8609438212337417 0.7742421173277976 1.0 12.71798248588113 -9.040168556925273 0.7203259246064394 1.0023059219282817 0.7491603887304583 0.3313262740432166 0.10668019336750327 2.2572706092530486 1.9139764312618501 0.1262185123668145 0.04078058766020815 9.116569414331866e-10 9.040168556925273 -0.2531455331978234 RSTSLS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 RSTSLSSPR 9 1 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 RS(0.002)T(0.001)S(0.002)LS(0.952)S(0.043)PR 62.633 0.027897 1444600.0 3989.9 5152.1 6821.9 10419.0 8753.9 6687.7 7031.2 10729.0 5967.4 7282.4 True False 5258.605204924464 6817.415570193263 6731.437148649723 8017.06052194535 7538.572088313012 6269.517061788472 7656.963178760742 9071.079577892988 6282.82458131145 7027.44539259005 0.7482954204765925 0.970112920035174 0.9578782576877158 1.1408214612949936 1.072732930271064 0.8921473894908155 1.0895798901311242 1.2908075511277266 0.8940410391429365 1.0 12.778784622716923 -4.151048199264247 1.0408036029054581 1.0599112466789784 6.373855813923255e-10 0.38303050803640026 0.11281284171069474 5.980179645635688 2.0853803490706118 0.035624438090836 9.663849231631872 7.062391694370467e-05 4.151048199264247 -1.059911246041593 RSTSLSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 RSTSLSSPR 9 1 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 RS(0.001)TS(0.001)LS(0.13)S(0.868)PR 57.885 0.036991 1572200.0 10819.0 7316.7 10689.0 10364.0 8532.9 9721.2 8264.3 6584.8 10224.0 7032.6 True False 10664.719076038393 7299.7586306867115 9810.191680733207 11126.203133290488 8031.0115983268615 9305.446937224011 8692.185016469539 6890.753846994249 9072.46545650707 8248.175539649532 1.2929791594240903 0.8850149461049033 1.18937716996625 1.3489289940309932 0.9736712755107176 1.128182455925205 1.0538312351241343 0.8354276426186535 1.0999360298401897 1.0 13.009859321476617 -7.153609817894534 1.4870215610960387 0.9765978615493326 1.1428754877268856 0.19635030181822788 0.14134196063112422 0.6923752173404902 3.0280242527351002 0.0778680752965338 0.05068973904902992 7.020857883321397e-08 7.153609817894534 0.16627762617755304 RSTSPIIGS(ph)PPVR ddPTM_PC-9_AZD4547_30min_R2 1 RSTSPIIGSPPVR 13 1 Q86TB9-4;Q86TB9;Q86TB9-2 Q86TB9-4 PATL1 Protein PAT1 homolog 1 1 RSTSPIIGS(0.999)PPVR 64.327 0.019397 3973300.0 6990.4 5137.5 7897.3 12870.0 10377.0 10099.0 6129.0 9882.8 6672.6 7348.3 True False 9213.201790647377 6798.096405711816 7792.576641995851 9903.020339517867 8936.332670058378 9467.507933520013 6674.469126553734 8355.640344151447 7025.300013617112 7091.038253648447 1.2992740218129617 0.9586884406122181 1.0989330988288566 1.3965543528724602 1.2602290878152433 1.3351370553739204 0.941254141890945 1.1783380719815386 0.9907293914262116 1.0 12.791781163710251 -7.264957190642141 24.9898851644831 1.04244191050927 1.2164024151785968 0.3529551541289969 0.12989953924140085 429.96419833409243 3054365.338273479 0.05620181803432858 0.0395902288832683 5.433038835062436e-08 7.264957190642141 0.1739605046693269 RSVPPATPATPT(ph)SPATVDAAVPGAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSVPPATPATPTSPATVDAAVPGAGK 26 1 A0A0G2JHC2;Q6NYC8;Q6NYC8-3;Q6NYC8-4 A0A0G2JHC2 PPP1R18 Phostensin 1 RSVPPATPAT(0.002)PT(0.405)S(0.405)PAT(0.188)VDAAVPGAGK 110.89 0.00015076 0.0 12976.0 7805.0 8767.2 15771.0 18384.0 14745.0 21682.0 20169.0 15762.0 11810.0 True False 15172.580512317778 8579.828818551994 8976.243297791152 14887.402000271866 14781.787170648226 13971.746242910995 19628.123995913753 19639.58512082194 15992.489431225637 13951.059512091431 1.0875575793485541 0.6149947830926982 0.6434094335280708 1.0671162277939468 1.0595458472409784 1.001482807151789 1.40692712111951 1.40774864473915 1.1463279485952225 1.0 13.768087071123317 -6.378236294349256 1.1943515569210787 1.249501536245611 0.7805173244601189 0.4504170395278152 0.18539885689229035 0.3876487609907208 1.1463652636200146 0.08122935817939039 0.10584763114821161 4.1856576660590973e-07 6.378236294349256 -0.4689842117854921 RSVPPATPATPT(ph)SPATVDAAVPGAGK ddPTM_PC-9_Lapatinib_30min_R1 1 RSVPPATPATPTSPATVDAAVPGAGK 26 1 A0A0G2JHC2;Q6NYC8;Q6NYC8-3;Q6NYC8-4 A0A0G2JHC2 PPP1R18 Phostensin 1 RSVPPATPAT(0.017)PT(0.49)S(0.49)PAT(0.002)VDAAVPGAGK 87.51100000000001 8.234899999999999e-07 3511400.0 14028.0 11493.0 13293.0 11762.0 16939.0 17230.0 19220.0 17078.0 18734.0 16461.0 True False 13827.958147579855 11466.38866462781 12200.100852463893 12627.016716881779 15942.681323355338 16493.113065091726 20215.117555817746 17871.50622630418 16623.979642234288 19306.261917096235 0.7162421294686161 0.5939207037522889 0.6319245488770854 0.6540373673113904 0.8257777394617053 0.8542882685377128 1.0470756919503248 0.9256844387094149 0.8610667209229814 1.0 14.236781235929023 -6.513608935445883 1.6881579335069161 0.9486319742578034 0.6377849794588786 0.8461222779272907 0.05844885997387492 0.13384464441546667 0.7726680349761208 0.02277590300823353 0.02510206797537986 3.0647218492201426e-07 6.513608935445883 -0.31084699479892486 RSVS(ph)GSPESDELQELR ddPTM_PC-9_Lapatinib_30min_R1 1 RSVSGSPESDELQELR 16 1 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 RS(0.056)VS(0.888)GS(0.056)PESDELQELR 91.54700000000001 0.010718 0.0 5362.0 5473.9 3597.4 4428.9 5754.4 4839.2 3453.7 5150.1 3773.0 4232.7 True False 5285.536896729627 5461.225520865413 3301.6356583655775 4754.61608037729 5415.937505585688 4632.23869672617 3632.515686916115 5389.3924473643965 3348.045008548626 4964.316555281771 1.0647058538412695 1.1000961481908234 0.6650735547580686 0.9577584401459309 1.0909734391984767 0.9331070339980058 0.7317252327616598 1.0856262664455527 0.6744221427593055 1.0 12.277379398150925 -7.008862224336325 24.85141278418992 0.8732699603353923 0.9691415445986117 0.0837772038365806 0.15951258308195423 1168.936819261817 3277928.8960727532 0.05779782127224947 0.0484334257979528 9.798007682909449e-08 7.008862224336325 0.0958715842632194 RSVSDNDIR ddPTM_PC-9_AZD4547_30min_R2 2 RSVSDNDIR 9 1 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 ; 154.01 3.7337e-05 11314700.0 59280.0 54977.0 68925.0 110070.0 92160.0 81331.0 71131.0 96516.0 57399.0 73659.0 False True 78129.80689940165 72747.24011616911 68011.009465205 84695.06206454785 79365.17479739607 76245.35971295337 77461.52120099416 81601.66991703995 60432.99395761905 71080.22083005455 1.0991778864362554 1.0234526464134126 0.9568204582230025 1.1915419096269408 1.1165577972408105 1.0726663314010818 1.089776034688984 1.1480221778171047 0.850208303405642 1.0 16.11716054304786 -8.258889286276125 24.99997255148154 0.9251041492544261 1.0848286973934627 0.46607052192812504 0.06938160985592551 195.3516174381188 1915192.311953445 0.053073950676980425 0.017904136071606964 5.509481304827617e-09 8.258889286276125 0.15972454813903658 RSVSDNDIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSVSDNDIR 9 1 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 ; 120.45 0.0010606 8048800.0 39383.0 36983.0 43058.0 53106.0 56195.0 51799.0 53942.0 49339.0 46151.0 44590.0 False True 46049.76405029371 40654.42782786778 44084.66601837434 50130.64299197498 45183.99314918283 49082.569253072004 48832.223253739496 48043.90352899167 46825.87106588596 52673.81402575423 0.8742439654697916 0.7718147732379942 0.8369370404204955 0.9517184946482934 0.8578075080549636 0.9318210606331576 0.9270683005765172 0.9121022355719519 0.8889781750566043 1.0 15.684798306040065 -1.5228787520851468 0.10788411840247973 1.0315103364470017 0.3905183199757388 0.5005545991384945 0.043169951847872715 94.31092633263934 0.7153469216225995 0.43587707911499024 8.983136430584441 0.029999999529940435 1.5228787520851468 -0.6409920164712629 RSVSDNDIR ddPTM_PC-9_Lapatinib_30min_R1 2 RSVSDNDIR 9 1 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 ; 115.7 0.0012422000000000002 11396000.0 70073.0 54828.0 72790.0 55137.0 59597.0 66292.0 56483.0 50518.0 55132.0 50694.0 False True 69073.74617018556 54701.04913462227 66805.48717752553 59191.95891164008 56091.621632210146 63456.845694199736 59407.41336655845 52865.250705026076 48922.453594302395 59456.390354491 1.1617547879774395 0.9200196784312599 1.123604826650554 0.9955525143508659 0.9434077867455555 1.067283858233862 0.9991762535929185 0.8891432929216319 0.8228291913218554 1.0 15.859544258271775 -7.694564816063165 4.286855864654757 0.8911557632930898 1.028240085286942 0.34038870698076407 0.08067544413044339 0.2222851051068599 7.9556726637309945 0.03923234821408693 0.02095683635342789 2.0203898774113983e-08 7.694564816063165 0.13708432199385223 RSVSGS(ph)PESDELQELR ddPTM_PC-9_AZD4547_30min_R2 1 RSVSGSPESDELQELR 16 1 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 RS(0.01)VS(0.071)GS(0.918)PESDELQELR 75.608 0.041238 0.0 4830.1 3892.8 8314.8 9692.5 8304.8 8478.0 5390.5 7806.6 5186.7 6913.1 True False 6365.971327678805 5151.071472146956 8204.540319206191 7458.043872632236 7151.821871282728 7947.869319772521 5870.2440572177975 6600.269347821738 5460.858373142087 6671.074473183879 0.9542647669829628 0.7721501975211084 1.2298678949225463 1.1179674132872877 1.07206446278352 1.191392683700512 0.8799548080020351 0.9893862487000017 0.8185875296540953 1.0 12.703703431722806 -7.292652699226554 24.921683758188625 0.9210976539633035 1.054780593009874 0.20610278056362685 0.12910580873362867 1189.1464963089227 949446.7103040068 0.05712767446007616 0.03852022912142002 5.0973834055228815e-08 7.292652699226554 0.13368293904657047 RSY(ph)DVPPPPMEPDHPFYSNISK ddPTM_PC-9_AZD4547_30min_R2 1 RSYDVPPPPMEPDHPFYSNISK 22 1 P18669;Q8N0Y7 P18669 PGAM1;PGAM4 Phosphoglycerate mutase 1;Probable phosphoglycerate mutase 4 1 RS(0.083)Y(0.917)DVPPPPMEPDHPFYSNISK 112.56 3.6882e-06 16705000.0 26436.0 26924.0 47441.0 75994.0 51260.0 47207.0 36079.0 55643.0 45414.0 45539.0 True False 34842.09809704081 35626.656472483686 46811.901342601275 58474.75739559592 44143.43381200662 44255.13882737689 39289.961105715796 47044.65289893744 47814.49132548143 43944.69347099283 0.7928624674567251 0.8107157806436915 1.065245827087201 1.3306443344335568 1.0045225105767315 1.0070644560665551 0.8940774870042147 1.070542292665913 1.0880606405194972 1.0 15.42340134320492 -5.255090815049801 8.183100029085708 1.060364996528373 0.8010059487628551 0.4843584087729559 0.10551938317962509 0.11663828431058493 77.2523331581774 0.029427046720629967 0.07094972986487882 5.557880246289781e-06 5.255090815049801 -0.2593590477655179 RSY(ph)DVPPPPMEPDHPFYSNISK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSYDVPPPPMEPDHPFYSNISK 22 1 P18669;Q8N0Y7 P18669 PGAM1;PGAM4 Phosphoglycerate mutase 1;Probable phosphoglycerate mutase 4 1 RS(0.117)Y(0.883)DVPPPPMEPDHPFYSNISK;RS(0.333)Y(0.667)DVPPPPMEPDHPFYSNISK 104.95 2.1947e-05 19421400.0 40863.0 32040.0 47665.0 47824.0 57428.0 51503.0 53351.0 47911.0 50183.0 34852.0 True False 47780.298818961266 35220.71945501675 48801.514370519144 45144.57632749995 46175.39565034738 48802.09201415023 48297.20705220898 46653.38701590062 50916.83143809137 41170.391711719814 1.1605500174378918 0.855486624991003 1.1853546284483616 1.0965301628317716 1.121568042725297 1.1853686590078745 1.1731053566454264 1.1331781184539953 1.2367341995339112 1.0 15.329319554656706 -5.301739129007099 24.999560502608198 1.1466167205609321 1.0080179425934923 0.25379963137344363 0.09119768315246339 533.9368141825134 331221.6202992315 0.02189343758406818 0.04557587852104098 4.991842462464651e-06 5.301739129007099 -0.1385987779674398 RSY(ph)WEMRGNALEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RSYWEMRGNALEK 13 2 H0YBP1;E7ESA6;Q05397-7;Q05397;Q05397-5 H0YBP1 PTK2 Focal adhesion kinase 1 1 RS(0.31)Y(0.69)WEMRGNALEK 79.036 0.01902 0.0 6453.3 6062.6 6233.4 6672.9 7943.2 6102.4 6723.7 8021.4 6196.7 4524.4 True False 7545.716231515127 6664.454861672428 6382.027896301143 6299.039046833688 6386.786980738303 5782.379401338764 6086.782460627492 7810.846749375829 6287.3150144953615 5344.637904869303 1.411829269975521 1.246942258819945 1.1940992093190657 1.1785717122379544 1.1949896502660238 1.0819029285539907 1.1388577802589859 1.4614360950925511 1.1763781057585248 1.0 12.383876494432952 -4.714492936426869 2.103846337577653 1.1903014304033983 1.4998800290135927 0.2821052433618846 0.11159245335687491 1.2466302790654868 5.360361031000128 0.030119258483200927 0.7881530439684961 1.9297767227458277e-05 4.714492936426869 0.30957859861019443 RSYS(ph)LSELSVLQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSYSLSELSVLQAK 14 1 Q9P0V3;Q9P0V3-2 Q9P0V3 SH3BP4 SH3 domain-binding protein 4 1 RS(0.001)Y(0.002)S(0.977)LS(0.014)ELS(0.007)VLQAK;RS(0.051)Y(0.003)S(0.841)LS(0.081)ELS(0.023)VLQAK 89.484 0.009377700000000001 0.0 20258.2 12043.900000000001 15903.599999999999 22524.0 23582.0 28722.0 23654.5 34066.0 27282.0 19856.9 True False 23687.513142311647 13239.538796637835 16282.802138738865 21262.05330379326 18961.27638480345 27215.76775780874 21413.77451625042 33171.80359591056 27680.94763752683 23456.798782866088 1.0098357137980005 0.5644222350710787 0.694161308602458 0.9064345693805426 0.8083488527280895 1.1602507234571315 0.9129026818396044 1.4141658417661302 1.180082068903036 1.0 14.517718517587166 -6.765880500904525 1.163510595251352 1.1855478353964157 0.7509097580728545 0.48247139874967215 0.1693052168425001 0.365886496676324 1.0481651668692487 0.08537482724124534 0.07667532747587992 1.714428979466876e-07 6.765880500904525 -0.4346380773235612 RSYS(ph)SPDITQAIQEEEK ddPTM_PC-9_Lapatinib_30min_R1 1 RSYSSPDITQAIQEEEK 17 1 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 RS(0.032)Y(0.071)S(0.449)S(0.449)PDITQAIQEEEK 114.96 7.3238e-05 3465500.0 25751.0 21228.0 24382.0 23665.0 23017.0 24302.0 17159.0 18952.0 22871.0 20470.0 True False 25383.786017844966 21178.84787024442 22377.406077241754 25405.403044125756 21663.18531316311 23262.660110728935 18047.409060368194 19832.579107677524 20295.027137692985 24008.2122254395 1.0572959693745079 0.8821501439329564 0.932072986822829 1.0581963707070938 0.9023239677216965 0.9689459545046605 0.7517181575579734 0.8260747997996533 0.845336876695385 1.0 14.551240356648766 -7.231499943023382 24.38552976446152 0.8412886859009754 0.9626227334379102 0.3138243498644746 0.079146956241446 553.1576197483364 450544.735095772 0.02900348524879382 0.022462741181966586 5.868134466048837e-08 7.231499943023382 0.12133404753693477 RSYS(ph)SPDITQAIQEEEKR ddPTM_PC-9_AZD4547_30min_R2 2 RSYSSPDITQAIQEEEKR 18 2 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 RS(0.049)Y(0.244)S(0.571)S(0.136)PDITQAIQEEEKR;RS(0.011)Y(0.176)S(0.671)S(0.142)PDITQAIQEEEKR 71.001 0.0030226999999999997 9904900.0 41564.0 36177.0 41975.0 57982.0 54986.0 55217.0 42746.0 53167.0 44323.0 53244.0 True False 54780.487415093216 47870.507770206634 41418.38407402222 44615.14571297007 47352.143027448226 51764.27226113224 46550.3111900254 44951.261806117705 46665.82329280212 51379.9437662123 1.0661842617881012 0.9316963830872566 0.806119684803142 0.8683377684486531 0.9216075292512722 1.0074801268111289 0.9060015986361805 0.8748795446459378 0.9082497930542655 1.0 15.648917690803145 -4.7825756940647075 4.512293256966517 0.9068860544536866 1.0762876849031298 0.39779176171871167 0.056361518111548894 0.19017078442649812 8.397018790466566 0.014742307191286596 0.10017960787130421 1.6497734339079763e-05 4.7825756940647075 0.16940163044944312 RSYS(ph)SPDITQAIQEEEKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RSYSSPDITQAIQEEEKR 18 2 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 RS(0.005)Y(0.117)S(0.791)S(0.086)PDITQAIQEEEKR;RS(0.052)Y(0.048)S(0.752)S(0.149)PDITQAIQEEEKR 101.23 0.00017225 8542600.0 22527.0 22856.0 26133.0 36771.0 30329.0 28798.0 34882.0 26570.0 24984.0 26819.0 True False 26340.37617146906 25124.99262995825 26756.109829954403 34710.84008319045 24386.250168548195 27287.78218401837 31577.72443618961 25872.56565324204 25349.343734915685 31681.072400912813 0.8314231235022879 0.7930600426655486 0.8445455851798593 1.0956333688436108 0.7697419411801718 0.8613276040249237 0.9967378640654782 0.8166568771989102 0.8001415928769288 1.0 14.951333550866375 -5.533235141997134 24.999920110962073 0.9002061777202398 0.8138818239689412 0.1367683373354056 0.09681739073981883 418.8814687753065 1011159.5035380538 0.02628999556244717 0.04559525224936307 2.92930678817658e-06 5.533235141997134 -0.08632435375129865 RSYS(ph)SPDITQAIQEEEKR ddPTM_PC-9_Lapatinib_30min_R1 1 RSYSSPDITQAIQEEEKR 18 2 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 RS(0.098)Y(0.364)S(0.44)S(0.098)PDIT(0.001)QAIQEEEKR 53.395 0.0155 4492900.0 28724.0 22707.0 25266.0 23064.0 21829.0 18430.0 22902.0 23607.0 28756.0 17658.0 True False 28314.390492663522 22654.42333661391 23188.72700958043 24760.20349924853 20545.06113746524 17641.791862428363 24087.75349965338 24703.867401590524 25517.196465895642 20710.161772193984 1.3671737963282924 1.0938795933033387 1.1196786999855421 1.1955581888545286 0.992028037417341 0.8518423012086127 1.1630886211615323 1.1928379736153774 1.2321099538756723 1.0 14.338051202399544 -4.761301414615279 24.4917880619955 1.0949407322309916 1.3671740610479317 0.35500360007275356 0.11067157675945437 3.1468006225293155 556025.449132269 0.0296681322252876 0.16650538284898242 1.7326010983851036e-05 4.761301414615279 0.27223332881694007 RT(ph)ADSSSSEDEEEYVVEK ddPTM_PC-9_AZD4547_30min_R2 1 RTADSSSSEDEEEYVVEK 18 1 P45973;F8VNY3 P45973 CBX5 Chromobox protein homolog 5 1 RT(0.386)ADS(0.114)S(0.114)S(0.262)S(0.123)EDEEEYVVEK 94.259 0.00082261 3073500.0 30881.0 30937.0 58966.0 73595.0 65555.0 55871.0 39772.0 63501.0 38827.0 47172.0 True False 40700.515635297255 40936.780243991554 58184.07231230006 56628.80978141552 56453.819811667854 52377.37753774594 43311.63095142683 53688.37955781366 40879.31595310848 45520.52263803932 0.8941135399285988 0.8993038276274676 1.2781942943616031 1.244028110830466 1.2401839113440254 1.150632165501032 0.9514748171022398 1.1794324064493245 0.8980414455731137 1.0 15.474229501407015 -8.265645736712472 24.94364039858308 0.9490207156945035 1.109196878496815 0.16816086958431675 0.13817998115805916 718.6994209970262 4261790.720325983 0.12839216875217777 0.0376975272355987 5.424431924807987e-09 8.265645736712472 0.1601761628023114 RT(ph)ASPPPPPK ddPTM_PC-9_Lapatinib_30min_R1 1 RTASPPPPPK 10 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 RT(0.5)AS(0.5)PPPPPK 63.602 0.046217 22222000.0 178840.0 144220.0 172290.0 152620.0 153310.0 158810.0 146450.0 140190.0 170790.0 114430.0 True False 176289.7088047603 143886.06745085065 158124.98125863285 163844.18392539487 144292.60721905704 152018.06650419155 154032.46441464662 146703.7391887564 151553.831701569 134209.07303160918 1.3135453872275848 1.0721038764418134 1.1781988928676301 1.220813021238929 1.0751330290842034 1.1326958980514525 1.147705299911941 1.0930985206507196 1.1292368561838941 1.0 17.0341226808128 -1.5228787457886162 0.018379083813677 3.3253443633799555e-16 2.562219068589744 0.4567139748761081 0.06114358091541985 3540.4421639923107 5.036780424111063 266.93765664385955 459.2585508945811 0.02999999996488936 1.5228787457886162 2.5622190685897435 RT(ph)ASPPPPPKR ddPTM_PC-9_AZD4547_30min_R2 1 RTASPPPPPKR 11 2 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 RT(0.948)AS(0.052)PPPPPKR 66.056 0.020372 1115700.0 4094.2 4419.7 5482.2 4732.7 6109.9 3963.3 3239.1 6252.0 4918.0 4687.9 True False 5396.070435349692 5848.281593055868 5409.502445994154 3641.649134486108 5261.645849550904 3715.4742244697363 3527.373625031848 5285.897056667624 5177.955439704006 4523.778047885708 1.1928238693920163 1.292787031359595 1.1957930713515907 0.8050017255351679 1.1631087541993923 0.821321069499917 0.7797406476828472 1.1684695846512874 1.144608640144059 1.0 12.143312432144162 -5.60416304163133 8.140434986159656 0.9828234268398671 1.2431528996641028 0.3903144413423658 0.14051189566912875 0.25138978383535837 21.989313599333148 0.039496262976745904 0.0686129558518605 2.487923133727959e-06 5.60416304163133 0.2603294728242357 RT(ph)ASPPPPPKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RTASPPPPPKR 11 2 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 RT(0.5)AS(0.5)PPPPPKR;RT(0.5)AS(0.5)PPPPPKR 64.55 0.022144999999999998 14889300.0 56881.0 45656.0 52899.0 55558.0 63631.0 55046.0 64917.0 51293.0 51395.0 55693.0 True False 66509.82984904024 50188.42595000765 54160.31278057468 52445.26538146625 51162.96232895548 52159.290857055224 58767.59180162036 49946.61309942584 52146.55464521261 65789.70003445467 1.01094593552195 0.76286144979721 0.8232339219089071 0.7971652911322012 0.7776743517930765 0.7928184933164146 0.8932643220875491 0.7591859071141583 0.7926249035624571 1.0 16.005574114385908 -10.398330029016673 13.960328407319816 1.0000004810415417 0.8186919842897438 0.34622092516433334 0.07259203899592741 0.0 0.0 0.06689838590615999 0.016225241839672323 3.996409392396843e-11 10.398330029016673 -0.18130849675179794 RT(ph)ESVPSDINNPVDR ddPTM_PC-9_Lapatinib_30min_R1 1 RTESVPSDINNPVDR 15 1 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;A8MY87 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 RT(0.912)ES(0.088)VPSDINNPVDR 75.017 0.013077000000000002 14789000.0 18082.0 12515.0 21284.0 19083.0 11847.0 16231.0 10899.0 14590.0 21083.0 14843.0 True False 17824.147364167315 12486.022286419302 19534.11167861592 20486.42747902186 11150.18275209816 15536.837966308996 11463.296890783431 15267.904663413632 18708.410526167692 17408.59277294571 1.0238706595439127 0.717233291011525 1.1220959633781213 1.1767997417263583 0.6404987983535579 0.8924809816020531 0.6584849815430386 0.8770326736082383 1.0746652971997828 1.0 14.08751196671157 -4.4564208274530985 21.615823319496528 0.8995991450792113 4.419500186345137 0.035315345821634314 0.1805989319940172 1108.4509956106517 372368.6398261073 0.044632989541836754 6150.890794383474 3.496062375402697e-05 4.4564208274530985 3.5199010412659257 RT(ph)FSLTEVR ddPTM_PC-9_AZD4547_30min_R2 3 RTFSLTEVR 9 1 O95239;O95239-2 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 RT(1)FSLTEVR;RT(1)FSLTEVR;RT(1)FSLTEVR 140.63 0.0006485 30500200.0 67888.9 56989.7 88070.0 143421.0 103971.0 96778.0 72975.9 98029.0 78680.5 91008.8 True False 89476.1580231577 75410.50603067552 86902.13425608417 110357.5042823613 89536.42132009624 90726.45636104568 79470.61372694948 82880.87053232087 82839.39060057559 87822.60961292293 1.0188282768813495 0.858668472310791 0.9895189250137779 1.2565955938768005 1.0195144703024304 1.0330649107436163 0.9048992517668882 0.9437304459252269 0.9432581309720718 1.0 16.422304783743876 -7.245310811863252 23.139094359834292 0.9432828310370853 1.0296758975048885 0.15338288031559189 0.09341917497033514 629.8529877746245 903628.7949998598 0.039076401717207256 0.030141044797328605 5.684459650768818e-08 7.245310811863252 0.0863930664678032 RT(ph)FSLTEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RTFSLTEVR 9 1 O95239;O95239-2 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 RT(1)FSLTEVR;RT(0.975)FS(0.022)LT(0.002)EVR;RT(0.999)FS(0.001)LTEVR 108.98 0.0020366 11627500.0 23597.7 22061.800000000003 24880.9 30728.5 46590.7 52415.8 63158.0 73515.0 65921.0 54321.3 True False 27592.32453418013 24251.949702643207 25474.155017338708 29006.881768141153 37461.58678913841 49667.02317525767 57175.217015677576 71585.30914558095 66884.96991472042 64169.321682825816 0.42999246073634123 0.37793682505348913 0.3969833925197401 0.45203659642087995 0.5837927814525204 0.7739995043231146 0.8910054760790758 1.1155690487022856 1.0423200395559336 1.0 15.969596112500918 -6.914891874297246 1.0884120015762349 1.0650081712712536 0.3935391614639129 0.9767322976011281 0.04218628398083444 0.06536386614979381 0.16186919042802614 0.02459207873140238 0.019132418562824608 1.216488830506396e-07 6.914891874297246 -0.6714690098073407 down RT(ph)FSLTEVR ddPTM_PC-9_Lapatinib_30min_R1 4 RTFSLTEVR 9 1 O95239;O95239-2 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 RT(0.999)FS(0.001)LTEVR;RT(0.942)FS(0.019)LT(0.039)EVR;RT(0.87)FS(0.052)LT(0.078)EVR;RT(0.998)FS(0.002)LTEVR 103.21 0.0024857 19025200.0 35865.7 23118.399999999998 29595.6 31631.800000000003 58010.9 76486.8 78459.0 78783.0 92100.0 83812.2 True False 35354.24854103613 23064.870765190248 27162.36401031975 33958.10809259147 54598.812915817565 73215.63786343927 82521.22311716454 82443.54579148159 81726.72814400434 98299.02709726318 0.35966020809193194 0.2346398682295037 0.27632383363716934 0.34545721453571665 0.5554359440586741 0.7448256613058353 0.839491758504516 0.8387015439115874 0.8314093288343416 1.0 16.584889517286214 -6.592065451807057 1.310209755329677 0.8747473500440622 0.2751225221981891 0.9605456035386094 0.05298609360491575 0.07427577619761976 0.266148948466753 0.02290356354455001 0.02409554230276399 2.558200315690022e-07 6.592065451807057 -0.5996248278458731 down RT(ph)GSNISGASSDISLDEQYK ddPTM_PC-9_AZD4547_30min_R2 1 RTGSNISGASSDISLDEQYK 20 1 P22059 P22059 OSBP Oxysterol-binding protein 1 1 RT(0.61)GS(0.389)NIS(0.001)GASSDISLDEQYK 135.25 7.2336e-05 8273300.0 29963.0 51334.0 67002.0 81434.0 81440.0 99788.0 88427.0 99891.0 83001.0 85764.0 True False 39490.610730883425 67926.71160891677 66113.5097016709 62660.6494427581 70133.46175672676 93548.2405852159 96296.83169420266 84455.14121682434 87388.26341010017 82761.42846452992 0.4771620241887004 0.8207532526825458 0.7988444729419573 0.7571238269481216 0.8474172456651677 1.1303362245047404 1.16354724031224 1.0204650014350625 1.0559056921975825 1.0 16.336670925918327 -6.585919222782747 3.192987689126967 1.0808495680582266 0.730313067525597 0.7437774688040151 0.09987380288099378 0.1322273876976501 2.7423912849628547 0.03515131471670349 0.03593921617341325 2.594661915058573e-07 6.585919222782747 -0.35053650053262964 RT(ph)GSNISGASSDISLDEQYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RTGSNISGASSDISLDEQYK 20 1 P22059 P22059 OSBP Oxysterol-binding protein 1 1 RT(0.483)GS(0.483)NIS(0.028)GAS(0.005)S(0.001)DISLDEQYK;RT(0.469)GS(0.469)NIS(0.061)GAS(0.001)S(0.001)DISLDEQYK 87.51100000000001 0.00062109 9685000.0 40880.0 47215.0 56882.0 71370.0 84668.0 59942.0 71965.0 61385.0 64727.0 55166.0 True False 47800.176583195935 51902.19316693556 58238.2826061863 67371.37028466201 68077.91319432363 56798.535998139785 65147.954218519175 59773.70879278371 65673.50992354656 65167.15910618427 0.7335010032478118 0.7964470736305294 0.8936753328665447 1.0338239568627838 1.0446659656192245 0.8715822014826742 0.9997052980684059 0.9172366819825244 1.0077700305538444 1.0 15.991857483100443 -5.324024014188293 2.382346481358413 0.9769497468067898 0.7479558491364394 0.7390825508125574 0.05135458986319721 0.15657116831373097 1.686106864921302 0.014411630815267985 0.04446939174860509 4.742157629112445e-06 5.324024014188293 -0.2289938976703504 RT(ph)GSNISGASSDISLDEQYK ddPTM_PC-9_Lapatinib_30min_R1 2 RTGSNISGASSDISLDEQYK 20 1 P22059 P22059 OSBP Oxysterol-binding protein 1 1 RT(0.788)GS(0.206)NIS(0.005)GAS(0.001)S(0.001)DISLDEQYK;RT(0.461)GS(0.461)NIS(0.031)GAS(0.035)S(0.013)DISLDEQYK 78.418 0.0015241 17148000.0 27776.0 42040.0 39984.0 41883.0 46950.0 46970.0 42686.0 41045.0 48294.0 39057.0 True False 27379.909146505426 41942.65896292991 36696.66986270341 44963.21553759222 44188.4933072515 44961.202592417816 44896.07221579789 42952.100542139306 42854.621161634605 45807.950409818826 0.597710853717581 0.915619637807231 0.801098270811033 0.981559208288753 0.9646468115670113 0.9815152651488308 0.980093451336223 0.9376560216702606 0.935528020316072 1.0 15.483310393185976 -4.239565629272593 1.000847693425913 0.9619547288497613 3.63501197606784e-17 0.7948567126963362 0.053026305847305534 2.1290578877328605 0.8075929327616248 0.01638805803627706 2.8567842520185955 5.760157662167265e-05 4.239565629272593 -0.9619547288497613 RT(ph)KQT(ph)AT(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 RTKQTATK 8 2 Q8IY92 Q8IY92 SLX4 Structure-specific endonuclease subunit SLX4 3 RT(1)KQT(1)AT(1)K 51.346000000000004 0.03889 3861000.0 29999.0 21130.0 38913.0 48220.0 46541.0 35074.0 31367.0 38831.0 37892.0 41855.0 True False 39538.057982036895 27959.859280329092 38396.98819469747 37103.62399157353 40079.585506137366 32880.81723539763 34158.60223406934 32830.561197610456 39894.89376194881 40389.66918967051 0.9789151229827004 0.6922527428741534 0.95066359702984 0.9186414431208718 0.9923226981118121 0.8140897881829339 0.8457262195850136 0.8128455086729637 0.9877499509738933 1.0 15.30169870928997 -8.339709096027542 7.776904370012876 0.9962663629361899 0.8744132705989344 0.23172997234402082 0.08607751591155352 0.4965718615512121 43.749696367778476 0.08157055371531098 0.021134299074661335 4.573944640874324e-09 8.339709096027542 -0.1218530923372555 RT(ph)NSTGGSSGSSVGGGSGK ddPTM_PC-9_AZD4547_30min_R2 1 RTNSTGGSSGSSVGGGSGK 19 1 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 RT(0.397)NS(0.397)T(0.078)GGS(0.097)S(0.025)GS(0.007)SVGGGSGK 58.92 0.019628 42314000.0 3526.4 3538.1 4111.2 5472.6 6207.2 4899.8 3033.2 4562.0 3974.0 5438.8 True False 4647.721846323373 4681.721633683501 4056.6828017896382 4210.976620827153 5345.437424071156 4593.414731425026 3303.148923913001 3857.0477243310506 4184.057526918204 5248.389267441879 0.8855520445396997 0.8920301820458187 0.7729386284197834 0.8023369468704877 1.018491036332101 0.8752046575356071 0.629364316477804 0.7349012292701026 0.7972079267964737 1.0 12.357659011740996 RT(ph)NSTGGSSGSSVGGGSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RTNSTGGSSGSSVGGGSGK 19 1 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 RT(0.46)NS(0.46)T(0.078)GGS(0.002)S(0.001)GSSVGGGSGK;RT(0.424)NS(0.424)T(0.148)GGS(0.003)S(0.001)GSSVGGGSGK 81.888 0.0017172999999999997 30198800.0 18377.3 16874.8 22491.1 25294.0 34547.0 29741.9 25173.4 24095.0 27793.1 20176.1 True False 21488.213921780007 18550.018622331983 23027.373121971723 23876.85918425443 27777.763347714535 28182.182406377404 22788.79331236673 23462.531780762798 28199.52150812063 23833.86721608027 0.9015831852617818 0.7783050251205825 0.966161844957984 1.0018038183977611 1.165474452629886 1.182442704361607 0.9561517275296203 0.9844198412305101 1.1831702028236077 1.0 14.540725437699658 -5.622987215945526 2.2353317117566567 1.0750596189275836 0.8414470303414086 0.5359776405176433 0.0847908346851262 0.2373816814492078 2.385027994174601 0.025701763204753078 0.05580721991367841 2.3823895972359666e-06 5.622987215945526 -0.23361258858617506 RT(ph)NSTGGSSGSSVGGGSGK ddPTM_PC-9_Lapatinib_30min_R1 1 RTNSTGGSSGSSVGGGSGK 19 1 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 RT(0.333)NS(0.333)T(0.333)GGS(0.001)SGSSVGGGSGK 104.55 0.00021827 35405000.0 6664.9 8694.5 7436.3 6854.8 6557.3 6835.9 6680.5 9258.0 7519.9 5882.4 True False 6569.857303807034 8674.368419438482 6824.916118948116 7358.924858942464 6171.612506147818 6543.544492261205 7026.383602062458 9688.160477990634 6672.929673942439 6899.165002194693 0.9522684704188257 1.2573069953652476 0.9892379899273378 1.0666399276726266 0.8945448477003473 0.9484545579326829 1.0184397097079567 1.4042511629898304 0.9672083030076413 1.0 12.752206049438627 RT(ph)PSDDEEDNLFAPPK ddPTM_PC-9_AZD4547_30min_R2 2 RTPSDDEEDNLFAPPK 16 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 RT(0.5)PS(0.5)DDEEDNLFAPPK;RT(0.622)PS(0.378)DDEEDNLFAPPK 98.169 0.0017722 7667800.0 118435.0 102116.0 128505.0 162507.0 160476.0 136287.0 129105.0 148759.0 116982.0 143528.0 True False 156094.86639896466 135123.000012782 126800.93973632454 125043.52185812184 138196.6774173929 127764.95234534555 140595.09489047492 125771.71469174989 123165.42969651372 138503.12840652335 1.127013289842865 0.9755952920874085 0.9155095714816529 0.9028209203412652 0.9977874074567401 0.922469794114253 1.0151041099794613 0.9080785115740835 0.8892609944160133 1.0 17.07955903761095 -4.774698857329524 3.4696711728624074 0.9428487488478111 1.1512315905651245 0.6189963569169888 0.04288499983907711 0.19437084601695934 3.795645094432084 0.010698925012361969 0.10873712323188607 1.679968515637448e-05 4.774698857329524 0.20838284171731336 RT(ph)PSDDEEDNLFAPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTPSDDEEDNLFAPPK 16 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 RT(0.61)PS(0.39)DDEEDNLFAPPK 107.72 0.0025800000000000003 0.0 14974.0 16881.0 17949.0 20364.0 20041.0 15355.0 19002.0 17041.0 20709.0 13960.0 True False 17508.802450018997 18556.834117357597 18376.972231961572 19223.07110097877 16114.10991552225 14549.75676906737 17201.9929974335 16593.69180643199 21011.82994742111 16490.837492700804 1.0617291242951588 1.1252814858900433 1.1143747089919243 1.165681919398412 0.97715533990646 0.8822933811279992 1.0431242806829832 1.0062370582316824 1.2741517801458775 1.0 14.009377047935812 -6.2620383116652265 24.99999042490003 1.024027012080998 1.1172041363652838 0.16125132788303664 0.09571159159135015 101.50877670653182 4237093.023372538 0.02998546876295628 0.036154774102753334 5.469677095337051e-07 6.2620383116652265 0.09317712428428582 RT(ph)PSDDEEDNLFAPPK ddPTM_PC-9_Lapatinib_30min_R1 1 RTPSDDEEDNLFAPPK 16 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 RT(0.839)PS(0.161)DDEEDNLFAPPK 75.358 0.010517 6653600.0 69629.0 62137.0 75014.0 57965.0 70538.0 74048.0 60124.0 59255.0 70195.0 53208.0 True False 68636.07769160529 61993.12559418593 68846.63848241392 62227.939465571566 66389.0935230438 70881.13965431886 63236.92653100865 62008.203621012646 62288.89991388047 62404.93190479653 1.0998502137028983 0.9934010614539432 1.1032243186715547 0.9971638068687426 1.0638436978719152 1.1358259273874929 1.0133321934792172 0.993642677402659 0.9981406599226311 1.0 15.929372430326456 -7.502267101796931 24.63613346501833 0.9982324709881757 1.0619465900322018 0.3639778610298803 0.04185903528623179 720.0589589588939 860656.3519880371 0.017374960368169344 0.011552370736715813 3.145812966607588e-08 7.502267101796931 0.06371411904402613 RT(ph)PSLALTPPQAEQEVDVLDVNVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTPSLALTPPQAEQEVDVLDVNVR 24 1 Q04721 Q04721 NOTCH2 Neurogenic locus notch homolog protein 2;Notch 2 extracellular truncation;Notch 2 intracellular domain 1 RT(0.663)PS(0.263)LALT(0.074)PPQAEQEVDVLDVNVR 94.927 0.0014990000000000001 0.0 3229.4 2255.1 3228.3 2884.2 5597.4 3472.5 3053.0 3314.4 2403.5 2946.2 True False 3776.0736364425875 2478.971424563305 3305.2749153959294 2722.607624702564 4500.629651272104 3290.3959870131207 2763.797738194108 3227.400511897081 2438.6466405247306 3480.3227378936313 1.084978009461258 0.7122820529177801 0.94970356611133 0.7822859630398377 1.293164453477089 0.9454284084597687 0.7941211049486807 0.927327939089458 0.700695545839135 1.0 11.765005381187056 -7.173788094844668 7.902465083374977 0.8497083560001796 0.9568479031849988 0.08870059057016133 0.16548108316627536 0.8241845607809262 66.72054854206324 0.0634486966542132 0.04909228741545922 6.70211545735218e-08 7.173788094844668 0.10713954718481922 RT(ph)PSPGPVESK ddPTM_PC-9_AZD4547_30min_R2 1 RTPSPGPVESK 11 1 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 RT(0.965)PS(0.035)PGPVESK 77.633 0.016372 9271300.0 37511.0 39580.0 51608.0 69502.0 66153.0 55250.0 52012.0 57843.0 50506.0 67053.0 True False 49438.71772273031 52373.46097091463 50923.64419993184 53479.3876951958 56968.79783389924 51795.2087659155 56640.967239404876 48904.69344990811 53175.64404995744 64705.49487934475 0.7640574856110421 0.8094128801359846 0.7870064867734696 0.8265045773147693 0.8804321478435179 0.8004762016347632 0.8753656446801363 0.7558043337911236 0.8218103292326745 1.0 15.981600612610618 -11.764459209141947 2.061821998208624 1.5836261393889932 0.8146356503088277 0.6729294222301064 0.0390129086592521 2902733.984976979 438852.1373163703 7900730.202631441 0.009929924988107278 1.7200488882486137e-12 11.764459209141947 -0.7689904890801655 RT(ph)PSRASLT(ph)RTLS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 RTPSRASLTRTLSR 14 3 A8MUU9 A8MUU9 Putative uncharacterized protein ENSP00000383309 3 RT(0.984)PS(0.102)RAS(0.153)LT(0.495)RT(0.291)LS(0.975)R 93.181 0.010838 6237800.0 12135.0 12526.0 20125.0 15446.0 14915.0 14746.0 15894.0 8544.7 16749.0 10218.0 True False 11961.952674713555 12496.996816595152 18470.400184746555 16581.95036634551 14037.72902401823 14115.347954604911 16716.913550060715 8941.71795596097 14862.551245210949 11984.167685370832 0.9981463034196029 1.0427922192586085 1.5412334564788774 1.383654735287727 1.1713561919827105 1.17783298141227 1.3949165256146394 0.7461275735382271 1.2401821833112183 1.0 13.548842095137692 -7.746630376829412 24.995960739657814 0.9948660338810437 1.2479487069491828 0.26339584450953246 0.19062583889834564 314.1082377231283 530181.8624398996 0.09209009519088554 0.05288503217057125 1.7921304673261928e-08 7.746630376829412 0.25308267306813914 RT(ph)PSRASLTRT(ph)LS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 RTPSRASLTRTLSR 14 3 A8MUU9 A8MUU9 Putative uncharacterized protein ENSP00000383309 3 RT(1)PS(0.001)RAS(0.004)LT(0.034)RT(0.968)LS(0.994)R;RT(1)PS(0.158)RAS(0.158)LT(0.161)RT(0.743)LS(0.779)R 87.99 0.016567 16146900.0 12742.8 15710.800000000001 23999.0 52160.0 35216.0 23467.0 20325.2 22077.2 17985.4 26882.0 True False 16794.745333294435 20789.00885856103 23680.75757933196 40135.317863966746 30326.866272407842 21999.604780266774 22134.10342487027 18665.676023586453 18936.071526078176 25940.869362244 0.6474241513948095 0.8013998516494856 0.9128744780542493 1.5471847648399268 1.1690767124615917 0.84806736709782 0.8532521834864046 0.7195470499825912 0.7299705827761865 1.0 14.662939209315676 -6.912425579850282 7.531990865365155 0.8091029162063147 1.0271460883064125 0.13287597056574763 0.23484830923839323 0.4934597656787748 36.44802873188544 0.09252314614349534 0.08157566070920907 1.2234167442251865e-07 6.912425579850282 0.21804317210009783 RT(ph)PSRASLTRT(ph)LS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTPSRASLTRTLSR 14 3 A8MUU9 A8MUU9 Putative uncharacterized protein ENSP00000383309 3 RT(1)PS(0.003)RAS(0.227)LT(0.316)RT(0.504)LS(0.951)R 77.027 0.04389 7685900.0 8248.1 9370.6 11255.0 16366.0 21236.0 14778.0 13033.0 11708.0 9852.6 9680.2 True False 9644.340422599278 10300.851239862051 11523.36188482519 15449.066079287903 17074.95824390154 14003.015664817824 11798.419889251174 11400.677405651415 9996.67563571207 11435.143631578958 0.8433947778290908 0.9008064587326671 1.0077146607063694 1.3510163559838648 1.4932001550682612 1.2245596658836453 1.0317684035615438 0.9969859385209328 0.8742063902114481 1.0 13.481186866441606 -7.5674784155138015 3.1081138231044645 0.951039064062004 1.1453774460033754 0.15614914139859448 0.18731271397880403 0.5482166808971047 10.832487848633393 0.11472926159299715 0.06266384799195053 2.7072077491174753e-08 7.5674784155138015 0.19433838194137143 RT(ph)PSRASLTRT(ph)LS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 RTPSRASLTRTLSR 14 3 A8MUU9 A8MUU9 Putative uncharacterized protein ENSP00000383309 3 RT(1)PS(0.001)RAS(0.021)LT(0.215)RT(0.773)LS(0.99)R 98.508 0.0068497 7380200.0 12173.0 11573.0 15313.0 9780.6 10954.0 11701.0 12913.0 6295.3 11218.0 7274.0 True False 11999.410787745195 11546.203429543006 14054.02424988939 10499.897951125147 10309.707256392609 11200.575506363226 13581.571956205747 6587.802620122541 9954.510709223032 8531.301208004254 1.4065158989448274 1.3533930109875976 1.6473482657843093 1.2307498815390452 1.2084566005851272 1.3128800910058833 1.591969574754109 0.7721920091089646 1.1668220903844646 1.0 13.05855008519361 -7.7616230499665795 24.999999999414822 0.9771302890093433 1.3848756852254005 0.5873118428037674 0.15868430338887685 3.509640371467233 477443.2670207399 0.08059750219635127 0.04256098188905559 1.731318421575723e-08 7.7616230499665795 0.4077453962160572 RT(ph)PT(ph)EWIQDFKT(ph)HFLDPK ddPTM_PC-9_AZD4547_30min_R2 1 RTPTEWIQDFKTHFLDPK 18 2 Q5T1C6 Q5T1C6 THEM4 Acyl-coenzyme A thioesterase THEM4 3 RT(1)PT(1)EWIQDFKT(1)HFLDPK 49.595 0.044429 0.0 7860.3 5077.5 10008.0 10304.0 9003.5 9459.2 7385.7 9337.8 7142.8 7455.3 True False 10359.71189560335 6718.702579075773 9875.287380888973 7928.571995213061 7753.519436722623 8867.714728661502 8043.012992003243 7894.857571297335 7520.353825684792 7194.292216216715 1.4399904235543053 0.9338934779339501 1.3726558616327822 1.102064213814001 1.07773206921528 1.2326041898427076 1.1179714070931703 1.0973779399037296 1.0453222637708681 1.0 12.812637044402937 -1.522878745610345 0.09877302852312993 0.9132643965928361 1.8822909530483616 0.24734003679366734 0.13194958671002954 209.36488373756987 1.4739002575234952 1.675732620260239 27.480979910062775 0.029999999977203897 1.522878745610345 0.9690265564555255 RT(ph)PT(ph)EWIQDFKT(ph)HFLDPK ddPTM_PC-9_Lapatinib_30min_R1 1 RTPTEWIQDFKTHFLDPK 18 2 Q5T1C6 Q5T1C6 THEM4 Acyl-coenzyme A thioesterase THEM4 3 RT(1)PT(1)EWIQDFKT(1)HFLDPK 48.216 0.046291000000000006 0.0 6172.2 6707.5 7842.9 7869.1 6520.1 6977.5 7378.0 6680.6 7808.8 5999.2 True False 6084.183296157144 6691.96919585757 7198.0870364694965 8447.819864548068 6136.600537009808 6679.0885903469325 7759.996739168749 6991.0050647293465 6929.290713690566 7036.153726568479 0.8647030085745995 0.9510834265301411 1.0230144644636683 1.2006303717681928 0.872152709489282 0.9492527949079238 1.1028748149528118 0.9935833320882898 0.984812297026087 1.0 12.780571287957356 -4.934391959097436 2.831808945131117 1.017121350322614 0.8599579004186348 0.24411611318237747 0.0829007198548493 0.4700770431319774 6.545794555542802 0.0221635309557033 0.14661115142748155 1.163075857318551e-05 4.934391959097436 -0.15716344990397912 RT(ph)PTAEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTPTAEER 8 1 A0A1B0GU26;F8WCB8;A0A1B0GTY1;A0A1B0GV98;A0A1B0GTC5;A0A1B0GTC3;A0A1B0GVH5;Q9C0B1 A0A1B0GU26 FTO Alpha-ketoglutarate-dependent dioxygenase FTO 1 RT(1)PTAEER 73.9 0.024356 5331200.0 5097.2 9761.7 9984.2 7936.7 11378.0 7212.3 8004.7 9149.5 8566.4 6508.5 True False 5960.055285711019 10730.777063172198 10222.261193289352 7492.032430128572 9148.56257765641 6834.07429147148 7246.436866990626 8909.335319696576 8691.667393963407 7688.439528742348 0.7751970036871639 1.3957028631175963 1.3295625406266907 0.9744542312026347 1.189911495493404 0.8888766395213331 0.9425107448527955 1.1587963053347887 1.1304852384506126 1.0 12.908475098376696 -5.779862650561396 24.999063151832775 1.0431333007950496 1.1897090939196522 0.09115590444119392 0.1780062396940211 501.65069538347535 680702.6731655253 0.0500252878847603 0.0743477354063441 1.6601118493557495e-06 5.779862650561396 0.14657579312460256 RT(ph)PTMPQEEAAEK ddPTM_PC-9_AZD4547_30min_R2 2 RTPTMPQEEAAEK 13 1 Q9NYV4-2 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 RT(0.978)PT(0.022)MPQEEAAEK;RT(0.857)PT(0.143)MPQEEAAEK 85.67200000000001 0.003684 7345800.0 40670.0 43069.0 45955.0 36524.9 45998.0 54015.0 45688.0 66772.0 44252.0 45683.0 True False 53602.21401144839 56990.21198980096 45345.60667353642 28104.64860907971 39611.97168327506 50637.43351114798 49754.143490616225 56453.92166791597 46591.07037775145 44083.65207482303 1.2159204487066892 1.2927742895046823 1.0286263623660643 0.6375299524045283 0.8985637491204629 1.1486669349717495 1.1286302551832295 1.2806090015431781 1.0568786428736119 1.0 15.427956127323858 -6.799357622439091 24.619536832185975 1.1408497734972336 1.009954097551706 0.07927612957262575 0.17902472172060713 375.9836990426839 244115.75548071248 0.0712563924463109 0.06284381020306248 1.5872391885250476e-07 6.799357622439091 -0.13089567594552753 RT(ph)PTMPQEEAAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTPTMPQEEAAEK 13 1 Q9NYV4-2 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 RT(0.94)PT(0.06)MPQEEAAEK 59.225 0.028758999999999996 9264000.0 34295.0 39464.0 36124.0 44841.0 42402.0 36171.0 42455.0 25175.0 25945.0 30857.0 True False 40100.46614287441 43381.72511150999 36985.33316103289 42328.704146483484 34093.63248530386 34274.12908459368 38433.3550524176 24514.18292511737 26324.396541882306 36451.1298361224 1.1001158626127296 1.190133894519766 1.0146553296787277 1.1612453259140547 0.9353244368167072 0.9402761790562839 1.0543803504913818 0.6725218953521781 0.7221832810185025 1.0 15.15367591244758 -6.882440848527899 0.856815291873734 0.805050467585497 1.1250518049654494 0.49074455142356777 0.11576185879247958 0.4859032231054335 0.7613296179996151 0.07870882840633732 0.06524623413377127 1.3108685722086974e-07 6.882440848527899 0.3200013373799524 RT(ph)PTMPQEEAAEK ddPTM_PC-9_Lapatinib_30min_R1 3 RTPTMPQEEAAEK 13 1 Q9NYV4-2 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 RT(0.997)PT(0.003)MPQEEAAEK;RT(0.997)PT(0.003)MPQEEAAEK;RT(0.894)PT(0.106)MPQEEAAEK 109.48 0.002668 18254900.0 47094.4 59081.0 63036.0 54219.0 68257.0 58139.0 59504.0 65760.0 57367.6 58852.0 True False 46422.82521994478 58944.20157442579 57853.42340599668 58206.44612928186 64242.2574584253 55652.530498628425 62584.82596469194 68815.44966868278 50906.25678039071 69024.48978463934 0.6725558619091115 0.8539606994319744 0.8381579289684418 0.843272385075059 0.9307168753998052 0.8062722473178395 0.9067046516382874 0.9969715079878347 0.7375100770642617 1.0 16.07482069828614 -4.033056370381738 1.0787765708869017 0.8864392557522031 2.34849348385411e-31 0.3954629485169212 0.07749624427425025 7.568848896181447 2.2482678357283357 0.02265929672686491 11.331891908165094 9.267095308990461e-05 4.033056370381738 -0.8864392557522031 RT(ph)QSLSALPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTQSLSALPK 10 1 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 RT(0.496)QS(0.496)LS(0.008)ALPK 64.22399999999999 0.044122 19744000.0 25929.0 25380.0 27337.0 37389.0 44958.0 39341.0 50525.0 41550.0 42901.0 38641.0 True False 30318.26757890625 27899.558669423364 27988.817756149812 35294.21554677351 36148.8026337034 37277.8887041276 45738.90623067719 40459.356525864 43528.34596428189 45646.307418012315 0.6641997851274707 0.6112117331623198 0.6131671834884338 0.7732107489782666 0.791932681490877 0.8166682216537304 1.0020286156296694 0.8863664733129868 0.9536005961153681 1.0 15.478210536906985 -6.473876535752237 0.7668005228244285 0.9668800807215516 0.6093125072772098 0.8894966114533982 0.0470882284257214 0.2088249379172624 0.2725252271774686 0.02926629549490641 0.0393995672318844 3.35833073629033e-07 6.473876535752237 -0.35756757344434187 RT(ph)SDPALCTLIVSAAADSAVR ddPTM_PC-9_AZD4547_30min_R2 1 RTSDPALCTLIVSAAADSAVR 21 1 Q6IA86-4;Q6IA86-7;Q6IA86-2;Q6IA86-3;Q6IA86-5;Q6IA86;Q6IA86-6 Q6IA86-4 ELP2 Elongator complex protein 2 1 RT(0.5)S(0.5)DPALCTLIVSAAADSAVR 75.225 0.0012474 1798400.0 4258.6 4258.1 7527.0 8127.4 6881.4 5223.1 6009.7 8181.6 4216.1 6249.9 True False 5612.7462156172705 5634.447553316108 7427.187061945567 6253.753497078279 5926.036391610265 4896.4987313167985 6544.551657668451 6917.321714464467 4438.954438661259 6031.092903321503 0.9306350118609785 0.9342332548406026 1.231482781148205 1.0369187802817876 0.9825808500390733 0.8118758589542121 1.085135275244089 1.1469433194529122 0.7360116167695897 1.0 12.558203743393255 -6.299071791943699 5.452746005085731 0.9660110971095487 1.0405175837245753 0.06329914775157075 0.1359186962686442 0.6565117069212298 53.3186142885197 0.04345677636692441 0.05049955286967162 5.022595556093581e-07 6.299071791943699 0.07450648661502657 RT(ph)SDPALCTLIVSAAADSAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSDPALCTLIVSAAADSAVR 21 1 Q6IA86-4;Q6IA86-7;Q6IA86-2;Q6IA86-3;Q6IA86-5;Q6IA86;Q6IA86-6 Q6IA86-4 ELP2 Elongator complex protein 2 1 RT(0.5)S(0.5)DPALCTLIVSAAADSAVR 91.27600000000001 0.00035236 1977500.0 5869.1 6934.6 9759.1 6817.2 7895.6 7286.2 6946.2 7801.9 6422.2 6733.5 True False 6862.622709991079 7623.021258825192 9991.793955592857 6435.2543856606035 6348.513859038842 6904.098845377972 6288.205649866988 7597.108391796352 6516.112525391271 7954.230247643323 0.8627639000045711 0.9583606485471976 1.2561610167813815 0.8090354673310141 0.798130511864398 0.867978249362786 0.7905486079850474 0.9551029018863543 0.8192008934267226 1.0 12.957506608475498 RT(ph)SDPALCTLIVSAAADSAVR ddPTM_PC-9_Lapatinib_30min_R1 3 RTSDPALCTLIVSAAADSAVR 21 1 Q6IA86-4;Q6IA86-7;Q6IA86-2;Q6IA86-3;Q6IA86-5;Q6IA86;Q6IA86-6 Q6IA86-4 ELP2 Elongator complex protein 2 1 RT(0.5)S(0.5)DPALCTLIVSAAADSAVR;RT(0.5)S(0.5)DPALCTLIVSAAADSAVR;RT(0.5)S(0.5)DPALCTLIVSAAADSAVR 106.23 0.00045523 1758400.0 16800.4 16585.600000000002 21725.1 16942.3 20678.4 17328.2 16338.3 15880.599999999999 21334.2 17391.2 True False 16560.823215183966 16547.19706221623 19938.94613931117 18188.293259855982 19462.137167298602 16587.113280007106 17184.217230084123 16618.47065098058 18931.31773691441 20397.245747682642 0.8119146780915488 0.81124663922315 0.977531299370478 0.8917033939213277 0.9541551544776442 0.8132035807771542 0.8424773345703522 0.8147409143643144 0.9281310805928404 1.0 14.316086736921578 -8.53403024663863 6.987493719434404 0.9999917545394555 0.8681484249794351 0.35781186632729556 0.05731454730954072 0.1593239196722789 62.47180140665258 0.05830291914899938 0.015084875694431555 2.9239487309997594e-09 8.53403024663863 -0.13184332956002043 RT(ph)SEEDTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSEEDTPK 9 1 A0A1B0GW41;Q8WYH8-2;Q8WYH8 A0A1B0GW41 ING5 Inhibitor of growth protein 5 1 RT(0.497)S(0.497)EEDT(0.005)PK 92.19 0.0082337 0.0 19453.0 23198.0 21616.0 21562.0 36807.0 33289.0 27908.0 32559.0 25550.0 27667.0 True False 22746.008685736575 25500.944129759002 22131.407419136518 20353.951044947178 29594.932571260306 31543.266238064716 25264.3522035772 31704.360749112067 25923.620414148907 32682.80808814849 0.6959624957680666 0.7802556029145552 0.6771574633197401 0.6227724065218243 0.9055198834641166 0.9651332943298407 0.7730165699176447 0.9700623233965251 0.7931882824826606 1.0 14.996244323889906 -6.273831241784359 24.8232748229267 0.8964486744257468 0.6989897848337598 0.6322881399719389 0.07729097424438335 455.6075300611673 912667.4290428738 0.023111070665572473 0.0263904401534108 5.323150661528003e-07 6.273831241784359 -0.19745888959198699 RT(ph)SET(ph)SISPPGSSIGSPNR ddPTM_PC-9_Lapatinib_30min_R1 1 RTSETSISPPGSSIGSPNR 19 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 2 RT(0.413)S(0.585)ET(0.63)S(0.239)IS(0.13)PPGS(0.002)S(0.001)IGSPNR 70.414 0.010742 5522200.0 15606.0 19142.0 18867.0 12481.0 12847.0 13406.0 14368.0 11961.0 17918.0 15982.0 True False 15383.455578210114 19097.67787508097 17315.82808872611 13398.894375395474 12091.364718173802 12832.656630912355 15111.904736836063 12516.751725777272 15899.886155095235 18744.467405323612 0.8206931275007079 1.0188434518900784 0.9237834137559036 0.7148186227787969 0.6450631248524957 0.6846103628032534 0.8062061412608679 0.6677571282832178 0.8482442211497304 1.0 14.19417721383833 -5.7539564664345155 24.37555513539415 0.745988978850449 0.9308804431492933 0.28130697787047876 0.10935178319912225 128.06083942931565 417150.7737153622 0.0283087524059778 0.04777942164200618 1.7621526752829895e-06 5.7539564664345155 0.1848914642988443 RT(ph)SETSISPPGSSIGSPNR ddPTM_PC-9_Lapatinib_30min_R1 2 RTSETSISPPGSSIGSPNR 19 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 RT(0.409)S(0.409)ET(0.166)S(0.015)IS(0.002)PPGSSIGSPNR;RT(0.744)S(0.25)ET(0.003)S(0.003)IS(0.001)PPGSSIGSPNR 70.944 0.009696399999999999 23397600.0 37760.0 32659.0 31451.0 29245.0 22215.3 31132.0 26426.0 22071.8 33186.0 34510.0 True False 37221.53547566409 32583.380092062976 28865.220184370857 31395.774858460096 20908.639730960243 29800.556932236563 27794.208976588958 23097.336405067363 29448.24321592758 40475.00751831544 0.9196177532226741 0.8050246828816177 0.7131615768399546 0.7756829901576453 0.5165814909731351 0.7362705718770143 0.6867005265906803 0.5706567539145121 0.7275660962533951 1.0 15.30474372806087 -4.804245049278609 1.253765093760262 0.689550824960545 1.0186557094214008 0.19545694238609734 0.1227968064365163 1.8781799022897419 2.619728435172237 0.034786909983467076 0.7971997099893942 1.5694769820559864e-05 4.804245049278609 0.32910488446085584 RT(ph)SFLEGTLR ddPTM_PC-9_AZD4547_30min_R2 1 RTSFLEGTLR 10 1 E9PEW5;A0A0A0MQX1;Q9HD67-3;Q9HD67 E9PEW5 MYO10 Unconventional myosin-X 1 RT(0.986)S(0.014)FLEGTLR 81.771 0.013438 5615600.0 9187.6 8975.8 7306.8 7542.8 11220.0 12055.0 8862.3 16980.0 13068.0 8968.3 True False 12109.065686048285 11877.051818664357 7209.907057821688 5803.923995098317 9662.296671297587 11301.198944309706 9651.027531450014 14356.131161582896 13758.74780114924 8654.322546738065 1.3991927872635577 1.372383771753571 0.8330989536020011 0.6706387430967543 1.1164705982606855 1.305844435919399 1.1151684582275734 1.6588393931531846 1.5898122269934467 1.0 13.079205175690877 -7.7383094716434595 23.34985605858569 1.4682441283663648 1.1052624020671673 0.1976323982729461 0.2704689321470597 149.73807414289996 151162.14838973866 0.13552235902553833 0.07815401006513757 1.8267980037522357e-08 7.7383094716434595 -0.36298172629919745 RT(ph)SFLEGTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSFLEGTLR 10 1 E9PEW5;A0A0A0MQX1;Q9HD67-3;Q9HD67 E9PEW5 MYO10 Unconventional myosin-X 1 RT(0.988)S(0.012)FLEGTLR 89.46 0.007925 10192000.0 11090.0 14293.0 11986.0 12692.0 16354.0 12862.0 9842.1 10787.0 10655.0 6965.2 True False 12967.317962515737 15711.914580853761 12271.791697158125 11980.90838801918 13149.551098171292 12187.494077743051 8909.7850373666 10503.852679771247 10810.809217720405 8227.935623507143 1.5760111109119788 1.9095816131527517 1.4914788178577527 1.4561256840403352 1.5981592102644964 1.481233523865146 1.0828700472462887 1.2766085152345905 1.3139151437736112 1.0 13.006314790725915 -6.607849463230661 0.2885849491777589 0.9918475606473831 1.9124372933724683 0.6891958982115777 0.13968483660726216 1.6657574787803309 0.2709743817810537 0.2080961512047755 0.5292238852410177 2.466894273127583e-07 6.607849463230661 0.9205897327250852 RT(ph)SFLEGTLR ddPTM_PC-9_Lapatinib_30min_R1 1 RTSFLEGTLR 10 1 E9PEW5;A0A0A0MQX1;Q9HD67-3;Q9HD67 E9PEW5 MYO10 Unconventional myosin-X 1 RT(0.93)S(0.07)FLEGTLR 90.861 0.0071653 8343900.0 16105.0 21328.0 15999.0 22992.0 15342.0 9545.3 12506.0 11318.0 20373.0 19650.0 True False 15875.339746704718 21278.61632638841 14683.62397792597 24682.908379063578 14439.613723532533 9137.069770181082 13153.499487672045 11843.87559839037 18078.378202799136 23046.476318020832 0.6888402169441948 0.923291527640168 0.6371309772177337 1.0710057380773288 0.6265432304825577 0.39646276697997834 0.5707379864134315 0.5139126448206417 0.7844313357640288 1.0 14.492258566771325 -6.483236102360706 24.80153158335171 0.6057938685136898 0.8261736207615296 0.15770213950056622 0.1909902200120662 688.1187078841568 430506.20397664205 0.05622939295516213 0.06374704327884692 3.2867290066323096e-07 6.483236102360706 0.2203797522478398 RT(ph)SFSFQK ddPTM_PC-9_AZD4547_30min_R2 1 RTSFSFQK 8 1 H0Y7F8;Q9BPZ7-4;Q9BPZ7-3;Q9BPZ7-2;Q9BPZ7 H0Y7F8 MAPKAP1 Target of rapamycin complex 2 subunit MAPKAP1 1 RT(1)SFSFQK 120.45 0.0028993 70830000.0 49614.0 37587.0 62218.0 70064.0 72715.0 53403.0 42376.0 61984.0 50435.0 54739.0 True False 65390.21996469142 49736.26269615381 61392.94866748096 53911.82727800923 62619.7774022642 50063.70196789476 46147.38190681041 52405.797050621564 53100.89113490679 52822.60427125486 1.2379211677807345 0.9415715749406816 1.162247668672594 1.020620395790427 1.1854731183017568 0.9477704225033554 0.8736294346608544 0.9921093019478384 1.0052683291081763 1.0 15.68886781086522 -6.7829852117489065 24.958182649097463 0.9576293927267101 1.0982189698966107 0.4135468624734838 0.08613734461301889 236.05805025663523 273442.1520400672 0.028733986968372257 0.025363072206520194 1.648218514399e-07 6.7829852117489065 0.14058957716990061 RT(ph)SFSFQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RTSFSFQK 8 1 H0Y7F8;Q9BPZ7-4;Q9BPZ7-3;Q9BPZ7-2;Q9BPZ7 H0Y7F8 MAPKAP1 Target of rapamycin complex 2 subunit MAPKAP1 1 RT(0.703)S(0.293)FS(0.004)FQK;RT(0.958)S(0.042)FSFQK 99.788 0.0043229 84774000.0 164291.0 127530.0 147355.0 156110.0 195971.0 152999.0 167219.0 147160.0 132352.0 114406.0 True False 192102.2214048397 140190.33558359178 150868.50204694932 147363.66281544892 157571.8893395947 144975.46310065367 151378.8057592795 143297.20592890872 134287.3976146158 135146.90216260217 1.4214326657203853 1.037318157799293 1.1163297096179954 1.0903961574949614 1.16593045654877 1.0727250183376476 1.1201056282973314 1.060306996578438 0.9936402201291136 1.0 17.04416891723156 -4.756941711504015 24.99996359325081 1.081126583545092 1.4214331732639307 0.802813007911771 0.05166708710966908 58.52008478447006 325239.2122719991 0.01274817637482718 0.09877893547775664 1.750081558697598e-05 4.756941711504015 0.34030658971883865 RT(ph)SFYLPK ddPTM_PC-9_AZD4547_30min_R2 2 RTSFYLPK 8 1 Q9NS23-3;Q9NS23-4;Q9NS23-2;Q9NS23-5;Q9NS23 Q9NS23-3 RASSF1 Ras association domain-containing protein 1 1 RT(0.861)S(0.139)FYLPK;RT(0.5)S(0.5)FYLPK 94.616 0.005669899999999999 25420000.0 55244.0 40418.0 56889.0 87918.0 72416.0 65725.0 54491.0 64239.0 51520.0 53992.0 True False 72810.44285341665 53482.32808293145 56134.61468938775 67649.86341955957 62362.28839114849 61615.20535999634 59340.593436945564 54312.338615366556 54243.2420198354 52101.75651388575 1.3974661839665958 1.026497601259907 1.0774034974123605 1.2984180946285382 1.196932552063349 1.1825936299014244 1.1389365235916868 1.0424281684417234 1.0411019829125898 1.0 15.669044390655062 -7.689382828029455 1.955340243100156 1.0194788733910973 1.1887248890477884 0.373999061936513 0.09759204984205462 0.4083257990013742 3.0740904017474655 0.06700111041645762 0.029285278118072265 2.0446415026659644e-08 7.689382828029455 0.16924601565669106 RT(ph)SIETNIR ddPTM_PC-9_Lapatinib_30min_R1 1 RTSIETNIR 9 1 A0A0C4DG88;P14859-4;P14859-5;P14859-3;P14859;P14859-2;P14859-6;A0A0A0MT46;H0YLC5;Q9UKI9-3;Q9UKI9;Q9UKI9-2 A0A0C4DG88 POU2F1;POU2F3 POU domain protein;POU domain, class 2, transcription factor 1;POU domain, class 2, transcription factor 3 1 RT(0.989)S(0.011)IETNIR 85.676 0.010401 2627700.0 8420.8 9789.4 14794.0 13108.0 10979.0 11717.0 12565.0 11587.0 9759.4 8542.8 True False 8300.717847814403 9766.733245758944 13577.694426491451 14072.00604700616 10333.236805544497 11215.891223661052 13215.55421898283 12125.374320423154 8660.193600961953 10019.41159743452 0.828463604583308 0.9747811187095782 1.3551389015666382 1.4044742957370182 1.0313217203483618 1.1194161567863816 1.3189950418212868 1.2101882633035923 0.8643415351036585 1.0 13.290510166486891 -10.499960602188718 15.138949744747755 1.000019075019701 1.139284629769186 0.029820812259821028 0.19119554115710594 0.0 0.0 0.1933378356156873 0.046891312804222526 3.1625645449318245e-11 10.499960602188718 0.139265554749485 RT(ph)SLGEVSKGDTMENLDGK ddPTM_PC-9_AZD4547_30min_R2 1 RTSLGEVSKGDTMENLDGK 19 2 Q9ULJ8-3;Q9ULJ8;Q9ULJ8-4;Q9ULJ8-5 Q9ULJ8-3 PPP1R9A Neurabin-1 1 RT(0.5)S(0.5)LGEVS(0.001)KGDTMENLDGK 69.979 0.0036819 8935000.0 41063.0 31849.0 35745.0 50045.0 54705.0 42183.0 38290.0 41844.0 40856.0 43202.0 True False 54120.17983654061 42143.56640885952 35270.99794463192 38507.89843754244 47110.15502703516 39545.290341585765 41697.73582244124 35377.97127946259 43015.56475082287 41689.511129665385 1.2981725707507714 1.0108913553287278 0.8460400947118283 0.9236831374148934 1.1300241655631351 0.9485669001631963 1.0001972844620381 0.8486060479200094 1.0318078477109773 1.0 15.347396834090986 -4.775676783556038 4.251460747197036 0.9635522353308463 1.3255319528377016 0.6043089181782968 0.08003716601629116 0.1413975749319894 5.195653795670347 0.020234339680554294 0.15586826682925783 1.6761898883769224e-05 4.775676783556038 0.3619797175068553 RT(ph)SMGGTQQQFVEGVR ddPTM_PC-9_AZD4547_30min_R2 4 RTSMGGTQQQFVEGVR 16 1 A0A2R8Y6G0;A0A2R8Y804;A0A2R8Y543;A0A2R8Y5C3;A0A2R8Y750;A0A2R8Y5Z1;B4DGU4;A0A2R8YCH5;A0A2R8Y5A3;P35222 A0A2R8Y6G0 CTNNB1 Catenin beta-1 1 RT(0.94)S(0.06)MGGTQQQFVEGVR;RT(0.945)S(0.053)MGGT(0.002)QQQFVEGVR;RT(0.498)S(0.498)MGGT(0.004)QQQFVEGVR;RT(0.5)S(0.5)MGGTQQQFVEGVR 94.007 0.0014702 343848000.0 112026.1 146949.0 181811.0 211344.0 189197.0 177893.0 147662.9 237103.0 151556.0 164754.0 True False 147648.0695123661 194447.39050568317 179400.06734680274 162621.9060322503 162930.2623279404 166769.32258814498 160804.612039059 200464.179434911 159566.94075229377 158986.01260721448 0.9286859082197406 1.2230471556392724 1.1284015769992455 1.022869266078259 1.0248087844713136 1.0489559418045138 1.0114387385532932 1.2608919246888157 1.003653957574963 1.0 17.278540319003888 -12.441636827029285 1.2010927674636225 9.555306192261657e-05 1.0787870363014558 0.04363325862496514 0.09801768431259227 385045.3767483385 10854.692170914937 1041861.1898868176 0.0271230140554258 3.617122132198287e-13 12.441636827029285 1.0786914832395331 RT(ph)SMGGTQQQFVEGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RTSMGGTQQQFVEGVR 16 1 A0A2R8Y6G0;A0A2R8Y804;A0A2R8Y543;A0A2R8Y5C3;A0A2R8Y750;A0A2R8Y5Z1;B4DGU4;A0A2R8YCH5;A0A2R8Y5A3;P35222 A0A2R8Y6G0 CTNNB1 Catenin beta-1 1 RT(0.5)S(0.5)MGGTQQQFVEGVR;RT(0.491)S(0.491)MGGT(0.017)QQQFVEGVR;RT(0.498)S(0.498)MGGT(0.004)QQQFVEGVR 110.97 0.00023609 217142900.0 100753.2 120470.0 144815.0 99529.5 183171.0 111719.0 113257.0 111715.0 120389.5 78748.8 True False 117808.72679359252 132429.4654415068 148267.9388139458 93953.1847939929 147279.95745402563 105860.25896994052 102528.47705032764 108782.59962182665 122149.96868294221 93025.33406484229 1.266415519792439 1.4235849489043306 1.593844733850644 1.0099741725034157 1.5832241715075783 1.1379723602621172 1.1021565047953634 1.169386820433248 1.3130828274994306 1.0 16.505336045796234 -6.815378693580204 24.99991541288135 1.1524581106410063 1.369919432884666 0.31346834476107366 0.17054785022819652 122.31103806118148 56687.989067145725 0.05802541353347757 0.05117364404023948 1.529752974832447e-07 6.815378693580204 0.21746132224365966 RT(ph)SMGGTQQQFVEGVR ddPTM_PC-9_Lapatinib_30min_R1 4 RTSMGGTQQQFVEGVR 16 1 A0A2R8Y6G0;A0A2R8Y804;A0A2R8Y543;A0A2R8Y5C3;A0A2R8Y750;A0A2R8Y5Z1;B4DGU4;A0A2R8YCH5;A0A2R8Y5A3;P35222 A0A2R8Y6G0 CTNNB1 Catenin beta-1 1 RT(0.958)S(0.042)MGGTQQQFVEGVR;RT(0.844)S(0.155)MGGT(0.001)QQQFVEGVR;RT(0.5)S(0.5)MGGTQQQFVEGVR;RT(0.494)S(0.494)MGGT(0.011)QQQFVEGVR 139.0 5.8683e-05 152196000.0 225065.0 193053.0 158682.0 110181.0 109765.7 115259.0 74954.0 96008.1 143791.0 89216.9 True False 221855.5318281342 192605.99763964125 145635.7784902337 118284.07829304147 103309.4973336692 110329.64125185202 78834.75136726139 100468.98682080054 127595.74339364309 104637.9222909531 2.12022111076756 1.8406901955114012 1.391806864104996 1.130413101706514 0.9873045552874214 1.054394418737336 0.7534051674693599 0.9601584647432071 1.2194024938573815 1.0 16.67504627426257 -5.25835984552341 1.174648908798028 0.977384390223986 2.2633394246742995 0.9292154653186401 0.1078010762931768 0.18999501768493673 0.37502110176827125 0.036368334672966136 0.24483254475232524 5.5162019120904885e-06 5.25835984552341 1.2859550344503135 up RT(ph)SPQVLGSILK ddPTM_PC-9_AZD4547_30min_R2 1 RTSPQVLGSILK 12 1 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 RT(0.5)S(0.5)PQVLGSILK 130.69 0.00011773 149220000.0 120520.0 100760.0 144870.0 217770.0 193590.0 149720.0 133580.0 183770.0 126110.0 154590.0 True False 158842.8530282706 133328.69953080738 142948.92914362357 167566.49101296085 166713.37010663992 140357.98473181645 145468.361221251 155372.5691144928 132775.91714133238 149177.8511535339 1.0647884508323522 0.893756670308821 0.958244994402691 1.1232665554385908 1.1175477379350267 0.940876836919711 0.9751337755330374 1.0415257219021294 0.8900511444200879 1.0 17.186673825023313 -9.805098969461335 10.062699761710524 1.0000054635728164 1.001939057515216 0.0 0.08011335848917961 0.0 0.0 0.08018951840027633 0.01944881496657355 1.566394070769616e-10 9.805098969461335 0.0019335939423996695 RT(ph)SPQVLGSILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RTSPQVLGSILK 12 1 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 RT(0.932)S(0.068)PQVLGSILK;RT(0.5)S(0.5)PQVLGSILK 81.992 0.010695999999999999 228290000.0 137369.0 122509.0 151891.0 170611.0 166943.0 168786.0 162309.0 195986.0 157169.0 130158.0 True False 160622.8585385777 134670.88388622514 155512.65748982507 161052.218798325 134231.7175603528 159934.56502922872 146933.91650460116 190841.5751643315 159467.2992904645 153754.6150698387 1.0446701613842244 0.8758818967811449 1.0114340790303291 1.0474626646177192 0.873025616170167 1.0401935900043258 0.9556390644785561 1.2412087603201185 1.0371545544699974 1.0 17.23027018920377 -7.709072098387998 24.999998208573167 1.1043885764086943 0.9766505891225958 0.2779731161168345 0.0838807707102205 103.9813023003027 49640.11106349374 0.03704194242174486 0.021386139905493817 1.9540150375870556e-08 7.709072098387998 -0.12773798728609842 RT(ph)SPQVLGSILK ddPTM_PC-9_Lapatinib_30min_R1 2 RTSPQVLGSILK 12 1 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 RT(0.5)S(0.5)PQVLGSILK;RT(0.5)S(0.5)PQVLGSILK 74.78 0.017371 236720000.0 225304.0 168343.0 205978.0 195081.0 199164.0 166236.0 167802.0 160632.0 202040.0 133903.0 True False 222091.1236443063 167953.21212646304 189043.2839380728 209427.90751113903 187449.5650914896 159126.4737950428 176489.96649850806 168095.5491359461 179284.12762448023 157047.95513546787 1.4141611933293425 1.0694390256886084 1.2037296746398647 1.33352839475362 1.1935816988498682 1.0132349297880512 1.1237966539982627 1.070345354009536 1.1415884241843943 1.0 17.260845632739482 -6.59622177492865 5.9750329849775525 1.078507075967207 1.241297214655802 0.4714611302667021 0.09271688722852969 0.2033315122411207 12.527422358868003 0.030114037716999605 0.03014639617231072 2.533834383238139e-07 6.59622177492865 0.16279013868859482 RT(ph)SPSSLPGR ddPTM_PC-9_AZD4547_30min_R2 1 RTSPSSLPGR 10 1 Q5SNT2;H0Y4R5 Q5SNT2 TMEM201 Transmembrane protein 201 1 RT(0.975)S(0.025)PSSLPGR 84.352 0.010695999999999999 15865000.0 4842.8 5594.8 9654.1 10016.0 8048.7 5757.3 7630.8 8670.1 6537.4 6359.5 True False 6382.709663502398 7403.209687722922 9526.080326123114 7706.965945657413 6931.276935674948 5397.295120868876 8309.926417181628 7330.335264077739 6882.953617633384 6136.855840681149 1.0400618540183864 1.206352223340025 1.5522737658223669 1.255849272940065 1.1294508320902032 0.8794886601523646 1.3541016170031597 1.1944773438354261 1.1215765526063626 1.0 12.583283978553485 -6.23812112917191 5.641576251374208 1.122957954992989 1.2813994174562091 0.1633318567105736 0.16448610441233136 0.3541333562470299 37.87282449396906 0.05192616859496632 0.06528443330986924 5.779348329899565e-07 6.23812112917191 0.15844146246322022 RT(ph)SQEGPGDSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSQEGPGDSVK 12 1 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 RT(0.5)S(0.5)QEGPGDSVK 124.21 0.00027947 6145100.0 15675.0 22320.0 20514.0 21288.0 23414.0 17766.0 16989.0 15658.0 19067.0 15503.0 True False 18328.467904637873 24535.78209225887 21003.131559778234 20095.302376627194 18826.194778805344 16834.31968474444 15379.67893029142 15246.994091022354 19345.818803779912 18313.571178319522 1.000813425528713 1.3397595615488418 1.1468616009007977 1.0972902106835924 1.0279914602943576 0.9192264862395441 0.8397968250178652 0.8325516603267675 1.0563651739690407 1.0 14.160625526167099 -6.334363738744208 1.6504928577650495 0.9132722659095869 1.1768875981636515 0.5086721901766662 0.10008240481779125 0.2733512433860807 1.479843310175496 0.036273969824339274 0.04603317265609112 4.6305892717870234e-07 6.334363738744208 0.26361533225406464 RT(ph)SQEGPGDSVK ddPTM_PC-9_Lapatinib_30min_R1 2 RTSQEGPGDSVK 12 1 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 RT(0.5)S(0.5)QEGPGDSVK;RT(0.5)S(0.5)QEGPGDSVK 101.53 0.0022845 10733500.0 22093.6 23372.0 25207.0 22877.3 26066.0 23741.0 25683.0 23365.0 28586.0 24013.0 True False 21778.541212529966 23317.883569971396 23134.577761833858 24559.772958435587 24532.84912772774 22725.65277297404 27012.740072115866 24450.623198126097 25366.343656075023 28163.61505468876 0.7732864254194602 0.8279435549979004 0.8214349513338611 0.8720390798817855 0.871083100663366 0.8069153313182574 0.9591361059175786 0.8681635205795603 0.9006778287097758 1.0 14.781544908366081 -1.5229008404426938 0.036685439190506014 1.4201018992521024 2.8849618252971174e-06 0.7069590318882716 0.0356028688770473 499.0211960970883 1.4027709455393238 15.66230628558466 46.072415448406986 0.029998473759080775 1.5229008404426938 -1.4200990142902772 RT(ph)SSEELR ddPTM_PC-9_AZD4547_30min_R2 1 RTSSEELR 8 1 Q9P270 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 RT(0.955)S(0.039)S(0.005)EELR 87.696 0.0097897 33862000.0 28054.0 31555.0 31985.0 28674.0 24489.0 34684.0 24939.0 30684.0 37546.0 29286.0 True False 36974.58844055013 41754.53665834285 31560.858001372253 22063.652308883862 21089.125060909675 32515.20399705002 27158.52268675536 25942.49284817491 39530.60490832183 28260.706053964634 1.3083391607395118 1.4774767685779455 1.1167752830062307 0.780718367996634 0.7462348966313644 1.1505446443893264 0.9609994398192097 0.9179704427283936 1.3987833436587536 1.0 14.786509889376605 -5.431443468146721 4.6444415602384685 0.982503636378125 1.3862310638713653 0.4357926578739364 0.1786265804984313 0.19713857813461885 7.15394588343259 0.04836968617734216 0.10379746198586946 3.703024043058199e-06 5.431443468146721 0.4037274274932403 RT(ph)SSEELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSSEELR 8 1 Q9P270 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 RT(0.996)S(0.003)SEELR 110.81 0.0031886999999999996 33231000.0 37434.0 37910.0 43082.0 35561.0 42679.0 32094.0 39291.0 30523.0 29557.0 27563.0 True False 43770.836844798374 41673.45426153825 44109.23826939486 33568.63246031756 34316.35632376498 30410.93414174201 35569.07203779388 29721.803591791748 29989.215208649675 32559.953711412065 1.3443150820407022 1.2798990634600307 1.3547082609621415 1.0309791210959849 1.0539436458638853 0.9339980766337258 1.0924177704014097 0.9128331033644693 0.9210460025358893 1.0 14.990811028159637 -5.811034769697147 5.09532200007843 0.9897105070383339 1.322574886997191 0.8778658914675701 0.05720217863017572 0.062109607449141305 3.480900453629534 0.016557554056772145 0.025677473494281695 1.5451307311321685e-06 5.811034769697147 0.3328643799588571 RT(ph)SSEELR ddPTM_PC-9_Lapatinib_30min_R1 2 RTSSEELR 8 1 Q9P270 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 RT(0.892)S(0.096)S(0.011)EELR;RT(0.333)S(0.333)S(0.333)EELR 102.95 0.0034981 51842000.0 40470.0 47386.0 43815.0 40523.0 55324.0 41671.0 48362.0 53327.0 46130.0 51504.0 True False 39892.890378710945 47276.280628387176 40212.699830791054 43503.19660076521 52069.95109116894 39888.828469845495 50865.94772291659 55804.76709978473 40934.353629564845 60406.397775233825 0.6604083648084497 0.7826369783594362 0.6657026624964213 0.7201753159100177 0.8619939776067435 0.6603411217842826 0.8420622582426402 0.9238221306860359 0.6776493076425032 1.0 15.882413736215671 -14.522878745257872 0.09961485843780438 1.7694925819160694 0.5955176105392552 0.4542544601217975 0.08596245384379576 168.40985671775144 1.1381239873309579 26.88919471072751 1.425407848995118 3.0000000001551877e-15 14.522878745257872 -1.1739749713768142 RT(ph)SSLDTITGPYLTGQWPR ddPTM_PC-9_AZD4547_30min_R2 1 RTSSLDTITGPYLTGQWPR 19 1 Q86VQ1;H7C0Q2;H7C2L5 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 RT(0.333)S(0.333)S(0.333)LDTITGPYLTGQWPR 67.47800000000001 0.0077515 9243100.0 5453.0 2449.6 7187.1 9448.4 8700.7 7949.6 2728.6 4844.7 2082.5 5971.9 True False 7186.940570553924 3241.385295461151 7091.794358032287 7270.217356324829 7492.757990014162 7452.510255303567 2971.4401140013874 4096.062935130783 2192.5766984919883 5762.825598704888 1.2471209561103298 0.5624645826848562 1.2306106156719485 1.26157164255651 1.3001882256679869 1.2932041977772868 0.5156220786326027 0.7107733636866114 0.38046903570788926 1.0 12.492560644540983 -7.264373869953445 24.996288068637345 0.6276138838113687 1.1381961736280617 0.4814006591943767 0.25230379673193215 234.53669622369608 1997792.1808955346 0.10456025292428825 0.07396129707227275 5.440341099750091e-08 7.264373869953445 0.510582289816693 RT(ph)SSLDTITGPYLTGQWPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSSLDTITGPYLTGQWPR 19 1 Q86VQ1;H7C0Q2;H7C2L5 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 RT(0.333)S(0.333)S(0.333)LDT(0.001)ITGPYLTGQWPR 77.445 0.0028956 8229300.0 9021.7 5575.9 6546.6 9308.6 8758.4 8792.9 6723.8 4849.9 6696.6 5877.0 True False 10548.895623302817 6129.4385021606695 6702.695772118754 8787.06932088838 7042.254392700465 8331.78484498421 6086.8729879035545 4722.595263893814 6794.525106277479 6942.453577693601 1.5194765806136419 0.8828922561117033 0.965464975330163 1.2657008394152764 1.0143754385808972 1.2001210741623953 0.8767610643391174 0.6802487349814933 0.9786921914909993 1.0 12.761229909827541 -7.3017930424076765 8.766095646783373 0.8566825781641623 1.1214251534721544 0.3081509570965538 0.18576201129278522 0.4870165430533152 100.63168353432788 0.07536704038102533 0.050998440569535994 4.9912228126430365e-08 7.3017930424076765 0.26474257530799217 RT(ph)SSLDTITGPYLTGQWPR ddPTM_PC-9_Lapatinib_30min_R1 1 RTSSLDTITGPYLTGQWPR 19 1 Q86VQ1;H7C0Q2;H7C2L5 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 RT(0.333)S(0.333)S(0.333)LDTITGPYLTGQWPR 74.51899999999999 0.0036716 8177100.0 11832.0 8596.1 10527.0 7340.2 9412.0 5722.5 8730.2 5585.5 10440.0 7305.9 True False 11663.273510276944 8576.196258592807 9661.51069539513 7880.022794189397 8858.404664703967 5477.762014799037 9182.20703880333 5845.022720870247 9264.137261926227 8568.715080500175 1.3611461462663237 1.000873080505344 1.127533195424111 0.9196271226384882 1.0338078208322083 0.6392746127438385 1.0715967274602558 0.6821352636840226 1.0811582804297724 1.0 13.064863166249282 -1.5228787452834665 0.6187631657557069 0.897832270894591 32.07463620851292 0.4030487457154406 0.1538442087215266 173.4123248518103 1.2565821673080264 0.06263453230582515 7348.591956196827 0.029999999999783863 1.5228787452834665 31.17680393761833 RT(ph)SSTDSESKSHPDS(ph)SKIPR ddPTM_PC-9_AZD4547_30min_R2 1 RTSSTDSESKSHPDSSKIPR 20 3 E9PAT1;Q9NXH3 E9PAT1 PPP1R14D Protein phosphatase 1 regulatory subunit 14D 2 RT(0.409)S(0.203)S(0.233)T(0.112)DS(0.042)ES(0.001)KSHPDS(0.534)S(0.465)KIPR 60.207 0.034614 2215800.0 779.75 2150.6 9747.1 21277.0 12818.0 7302.3 3310.3 12724.0 5285.9 7152.7 True False 1027.6942801924488 2845.739392724836 9617.847085357993 16371.91637637309 11038.44195478543 6845.686026630677 3604.910287099171 10757.798168432328 5565.301882621274 6902.286150112442 0.1488918682653728 0.41228939670640535 1.3934292024681292 2.37195561301184 1.5992443249553785 0.9917998004935158 0.5222777220038096 1.5585847840076983 0.8062983425470722 1.0 12.752858569909103 -5.195410649119101 4.601346394084014 1.3136406261570093 0.2298692883269408 0.40418558254410053 0.48690233910336744 0.22463312431765098 9.395027019905958 0.13726054935230877 0.38824217755564405 6.376602584906942e-06 5.195410649119101 -1.0837713378300684 RT(ph)SSTLDSEGTFNSYR ddPTM_PC-9_AZD4547_30min_R2 2 RTSSTLDSEGTFNSYR 16 1 Q92609;Q92609-2;C9JNM0;C9JED7;F2Z3C3;C9K0P2;C9J397;C9JWX0;C9JW04;C9JDR8 Q92609 TBC1D5 TBC1 domain family member 5 1 RT(0.726)S(0.268)S(0.005)TLDSEGTFNSYR;RT(0.657)S(0.3)S(0.039)T(0.004)LDSEGTFNSYR 138.28 1.2974000000000001e-05 68698000.0 16639.9 18791.3 35010.0 37157.0 37927.0 23664.4 21370.1 28695.0 20989.9 28979.3 True False 21931.04206857882 24865.220241100233 34545.744524872374 28591.027719927377 32661.490717674114 22184.661327061185 23271.99750063077 24260.84709550186 22099.38326226987 27964.743527612412 0.7842389845958748 0.8891631785054024 1.2353320705681379 1.0223954920844016 1.1679524500349567 0.7933082348906948 0.8321906288055879 0.8675512103855585 0.7902587499309235 1.0 14.771321478578882 -6.780740015631492 24.998216039447893 0.8468542466351522 1.0246743314192397 0.2780339225274122 0.13086261442604208 322.9317354045576 418258.951112983 0.04791445188758086 0.04231816796756019 1.6567614639392366e-07 6.780740015631492 0.1778200847840875 RT(ph)SSTLDSEGTFNSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSSTLDSEGTFNSYR 16 1 Q92609;Q92609-2;C9JNM0;C9JED7;F2Z3C3;C9K0P2;C9J397;C9JWX0;C9JW04;C9JDR8 Q92609 TBC1D5 TBC1 domain family member 5 1 RT(0.48)S(0.48)S(0.029)T(0.011)LDSEGTFNSYR 64.565 0.025450999999999998 24393000.0 5182.7 4199.6 13323.0 9051.4 3962.3 3824.5 4537.7 10337.0 7977.0 4236.6 True False 6060.028747009042 4616.508533810499 13640.670847758869 8544.279403034732 3185.915758608542 3623.936487352537 4107.856205896955 10065.664702956838 8093.64853399866 5004.662043092855 1.2108767175143709 0.9224416142508438 2.7255928033312324 1.707264012927117 0.6365895901014053 0.7241121290805409 0.8208059146703782 2.011257626646116 1.617221795259691 1.0 12.289056934099785 -6.207368531246166 24.792441075122788 1.1493062051555014 1.667611865688829 0.151736487851878 0.5848555656985018 623.4024241642744 285840.24518151616 0.1886527859760449 0.24354952031952654 6.203424040405108e-07 6.207368531246166 0.5183056605333276 RT(ph)STPVIMEGVQEETDTR ddPTM_PC-9_AZD4547_30min_R2 2 RTSTPVIMEGVQEETDTR 18 1 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 RT(0.487)S(0.487)T(0.027)PVIMEGVQEETDTR;RT(0.409)S(0.409)T(0.183)PVIMEGVQEETDTR 70.994 0.0080327 9474600.0 26021.0 30182.7 32232.0 52197.0 38639.0 42906.0 39339.0 45525.0 31219.0 33282.0 True False 34295.136729577076 39938.66752013198 31804.58261998534 40163.78808561102 33274.641807688706 40223.08103729175 42840.09479025896 38490.157310427654 32869.172605148335 32116.807310252374 1.0678252168181528 1.2435441398118892 0.9902784642554627 1.2505535714563345 1.0360507346278696 1.2523997372693916 1.3338839809454996 1.1984428258577486 1.0234259055586696 1.0 14.971040863108273 -4.683670800947442 20.986175417524947 1.1577295294367786 1.0677898923807354 0.03245974480719904 0.11974661640660648 36332.955751121386 9791651.953761794 0.029205809501370496 204.27180982541978 2.071711129093446e-05 4.683670800947442 -0.08993963705604324 RT(ph)STPVIMEGVQEETDTR ddPTM_PC-9_Lapatinib_30min_R1 1 RTSTPVIMEGVQEETDTR 18 1 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 RT(0.697)S(0.228)T(0.075)PVIMEGVQEETDTR 112.61 0.0001481 1358200.0 1391.4 2389.2 1096.3 2414.6 2493.0 1123.6 2365.5 3180.3 2565.5 1227.6 True False 1371.5583808484898 2383.6679541920103 1006.1664458403795 2592.177738869475 2346.3666414265813 1075.5462472395282 2487.974015519608 3328.0683482559557 2276.546374087332 1439.7890243258196 0.9526106656429898 1.65556752685218 0.6988290845678008 1.8003872060931017 1.6296600417031697 0.7470165621960844 1.72801290569957 2.311497234682923 1.5811666401286282 1.0 10.491641710317115 -7.482248632109866 24.876827766702508 1.7717504060496483 1.2796535007065746 0.13474280831710572 0.4675727913843731 755.4987108795472 462574.4783791767 0.18862109950641281 0.12714900920982475 3.294210657461373e-08 7.482248632109866 -0.4920969053430737 RT(ph)SVPSPEQPQPYR ddPTM_PC-9_Lapatinib_30min_R1 1 RTSVPSPEQPQPYR 14 1 Q8TEH3 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 RT(0.774)S(0.226)VPSPEQPQPYR 210.02 2.1892999999999998e-60 0.0 12892.0 8807.3 9736.5 8255.9 7545.7 8054.7 9956.0 7532.7 10521.0 8547.8 True False 12708.157715896747 8786.907237968893 8936.002553976881 8863.066426875046 7101.8767614169865 7710.2192574227765 10471.472964917863 7882.696741473332 9336.01418895842 10025.275840772443 1.267611776247903 0.8764753586363032 0.8913473001545228 0.884072076184604 0.708397142803184 0.7690780163938818 1.0445072166823333 0.7862822795772544 0.931247612259124 1.0 13.29135431185455 -4.7611503738588885 6.634723548789937 0.8667718247409277 1.2781440762613847 0.5885765278365451 0.09772693359367277 0.08110546687467175 17.740246873742635 0.02413186885119992 0.15054330155170287 1.7332037744563303e-05 4.7611503738588885 0.411372251520457 RT(ph)TSFFSR ddPTM_PC-9_Lapatinib_30min_R1 1 RTTSFFSR 8 1 Q9BZ67-2;Q9BZ67-3;Q9BZ67 Q9BZ67-2 FRMD8 FERM domain-containing protein 8 1 RT(0.872)T(0.125)S(0.004)FFSR 65.627 0.043522000000000005 2449800.0 5915.5 3852.7 6542.6 5744.7 4354.1 4520.8 4840.7 3818.2 5015.4 4630.1 True False 5831.143885230158 3843.7793098591847 6004.69268316635 6167.184401757419 4098.000398489962 4327.455922499517 5091.327760272994 3995.607511024398 4450.512837496626 5430.406615779554 1.073795076097276 0.7078253217153236 1.1057537875189767 1.1356763568748154 0.7546396961476299 0.7968935346249933 0.9375592143466251 0.7357842227530533 0.8195542530027908 1.0 12.406844512269204 -6.277300104690604 24.808945190037974 0.8301764884614893 0.9916236371202322 0.26491953924967626 0.13314574757287245 1056.629671827568 1652749.2626448497 0.04158353184940698 0.04731176057371358 5.280802134792076e-07 6.277300104690604 0.16144714865874288 RT(ph)VSVPSEGQFPEYPPEGATK ddPTM_PC-9_AZD4547_30min_R2 1 RTVSVPSEGQFPEYPPEGATK 21 1 Q9UJF2-2 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 RT(0.399)VS(0.272)VPS(0.328)EGQFPEY(0.001)PPEGATK 65.155 0.0037335999999999997 10538000.0 31130.0 23291.0 28002.0 56691.0 35818.0 37386.0 34623.0 40243.0 33474.0 46290.0 True False 41028.6924557755 30819.360269670855 27630.675183818235 43621.7658172189 30845.288963684212 35048.24750990978 37704.37992636154 34024.36904214257 35243.36730147457 44669.40118957945 0.9184965852048793 0.6899434388849709 0.6185593369956337 0.9765469125517415 0.6905238964985242 0.784614223082218 0.8440762338931304 0.7616929740728164 0.788982309207588 1.0 15.446999294441019 -14.522878745221789 0.3579750892538745 3.6539703087271747 0.7757721212750391 0.281236527472839 0.10224943393570571 612.1030463474863 4.9065498454785255 1250.5681256092453 0.07371767407340486 3.0000000004044413e-15 14.522878745221789 -2.8781981874521354 RT(ph)VSVPSEGQFPEYPPEGATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTVSVPSEGQFPEYPPEGATK 21 1 Q9UJF2-2 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 RT(0.686)VS(0.281)VPS(0.033)EGQFPEYPPEGATK 113.05 8.6592e-06 7120300.0 59236.0 43087.0 57529.0 69741.0 74375.0 67148.0 66009.0 80179.0 65552.0 53505.0 True False 69263.4848356702 47364.392607937145 58900.709539947435 65833.63787337263 59801.75265540474 63626.640672701724 59756.14965622499 78074.38620667261 66510.57398780006 63205.03295465304 1.0958539470324118 0.7493769149985114 0.9318990401002752 1.041588538061605 0.9461549161490034 1.0066704769911468 0.9454334071639123 1.235255842089153 1.0522986996228387 1.0 15.947751822914128 -7.725875080703803 24.99950214004325 1.107833068999225 0.9548699756228444 0.2698547003300309 0.10195517346466272 196.06256507823056 137819.843448731 0.04682592301425784 0.027033655595848947 1.8798574561859842e-08 7.725875080703803 -0.1529630933763807 RT(ph)VSVPSEGQFPEYPPEGATK ddPTM_PC-9_Lapatinib_30min_R1 1 RTVSVPSEGQFPEYPPEGATK 21 1 Q9UJF2-2 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 RT(0.579)VS(0.398)VPS(0.022)EGQFPEYPPEGATK 111.65 2.0166e-05 8761600.0 122190.0 96475.0 96755.0 93468.0 92147.0 71042.0 74980.0 75293.0 84230.0 68892.0 True False 120447.54819309842 96251.61806490629 88800.1773851009 100341.94852010776 86727.09462797247 68003.69926699059 78862.09752004236 78791.3876506101 74743.13041877832 80799.8904071803 1.4906894995292572 1.1912345125699932 1.099013586993797 1.2418574829055815 1.0733565873780622 0.8416310829667589 0.9760173822343979 0.9751422589009884 0.925039997481683 1.0 16.30206571573042 -1.5228787452803376 0.3881951467117325 0.9368115061298476 8.811766518599098 0.780854080784191 0.08330387776912983 33.776475067499995 0.45604032585474596 0.06654572411691993 201.48212094722052 0.029999999999999995 1.5228787452803376 7.8749550124692504 RTADSSSS(ph)EDEEEYVVEK ddPTM_PC-9_AZD4547_30min_R2 1 RTADSSSSEDEEEYVVEK 18 1 P45973;F8VNY3 P45973 CBX5 Chromobox protein homolog 5 1 RT(0.067)ADS(0.198)S(0.198)S(0.198)S(0.34)EDEEEYVVEK 74.627 0.0028436 2892600.0 20495.0 19735.0 29227.0 32265.0 31950.0 26702.0 22436.0 29432.0 23668.0 25289.0 True False 27011.98367751746 26113.952811040923 28839.43088341743 24826.802739280796 27514.29399714419 25032.31971886834 24432.760535708854 24883.96068007704 24919.04216082034 24403.63980737254 1.1068833948842711 1.0700843405806901 1.1817676015159346 1.0173401564376645 1.12746681291501 1.0257617272037376 1.0011932944661606 1.0196823456048303 1.021119896766059 1.0 14.574808721617243 -6.855763629000126 5.935359659395704 1.012552968445045 1.0986830499911244 0.5485240666949494 0.03962845965125512 0.16381672163686628 8.470364800006614 0.01342107603828419 0.011863412616423735 1.3939152548946376e-07 6.855763629000126 0.08613008154607948 RTADSSSS(ph)EDEEEYVVEK ddPTM_PC-9_Lapatinib_30min_R1 1 RTADSSSSEDEEEYVVEK 18 1 P45973;F8VNY3 P45973 CBX5 Chromobox protein homolog 5 1 RT(0.019)ADS(0.009)S(0.006)S(0.031)S(0.935)EDEEEYVVEK 116.94 5.2806e-05 4104300.0 42519.0 31145.0 46133.0 33172.0 38244.0 38256.0 33892.0 30853.0 42583.0 28280.0 True False 41912.671262970354 31072.885666043112 42340.12281852983 35611.57953854807 35994.56311059692 36619.88005909167 35646.76192517036 32286.543014414052 37786.85412113068 33168.160319268645 1.2636417232529382 0.9368287347547488 1.2765291294715808 1.0736676136318584 1.0852143370063945 1.1040672653109975 1.0747283413382984 0.9734197707570044 1.1392508284271305 1.0 15.017511374434754 -1.5228787855252852 0.10224829638185504 0.954354063830116 1.54851462933323 0.16968373564318184 0.09693590700278228 234.3168281814147 1.6988126349072554 1.091294975492474 19.54499914824051 0.029999997219977634 1.5228787855252852 0.5941605655031139 RTAFYNEDDS(ph)EEEQR ddPTM_PC-9_Lapatinib_30min_R1 1 RTAFYNEDDSEEEQR 15 1 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 RTAFYNEDDS(1)EEEQR 76.176 0.0065166 4643500.0 19014.0 20942.0 31304.0 24248.0 29240.0 28063.0 28195.0 24129.0 31504.0 21876.0 True False 18742.856873259436 20893.51008567264 28730.305956934455 26031.278808956744 27520.16068805185 26862.81090804813 29654.79914080546 25250.121427245198 27955.687768172767 25657.237452062265 0.7305095456312632 0.8143320232628267 1.1197739433410896 1.0145783955733088 1.0726080989611704 1.0469876563382299 1.1558063956110707 0.9841325074229944 1.0895829225732079 1.0 14.647078221498283 -5.150461174743391 4.272834351067079 1.0613535770833082 0.7493905186749605 0.8343141885442289 0.051745704499750744 0.07592791635400747 2.2821602411324036 0.01258205030640985 0.03750256293216741 7.0719441994541875e-06 5.150461174743391 -0.3119630584083477 RTAS(ph)PPPPPK ddPTM_PC-9_AZD4547_30min_R2 1 RTASPPPPPK 10 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 RT(0.375)AS(0.625)PPPPPK 68.033 0.019274 30410000.0 193820.0 206180.0 244740.0 326740.0 306920.0 265280.0 229360.0 252960.0 253480.0 244230.0 True False 255450.72829355643 272823.65293034783 241494.58768972475 251415.1410826778 264309.45582483563 248691.99966374823 249772.5956708053 213870.8444425208 266878.4353103239 235679.58203782677 1.0838899411004403 1.157604110510343 1.024673353548992 1.066766747075805 1.121477955533771 1.0552123247733567 1.0597973465122517 0.9074644591324604 1.1323782612084303 1.0 17.84646725140111 -7.322959359713477 2.770208920982846 1.012539157669855 1.0878879149222067 0.20133915026924032 0.06145666021613888 0.4112819785152742 6.214243257005975 0.027660715767637165 0.017815178204691105 4.7537970880976776e-08 7.322959359713477 0.07534875725235168 RTAS(ph)PPPPPKR ddPTM_PC-9_Lapatinib_30min_R1 1 RTASPPPPPKR 11 2 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 RT(0.391)AS(0.609)PPPPPKR 56.403999999999996 0.032169 9240600.0 23101.0 18687.0 19777.0 16750.0 20829.0 22045.0 17339.0 17267.0 19677.0 16160.0 True False 22771.575503795444 18643.731399625853 18151.01140142769 17981.85087636199 19603.87917138958 21102.186739404948 18236.728579621424 18069.2878562826 17460.76905200405 18953.234468153518 1.2014611828950756 0.9836701714924853 0.9576735533940777 0.9487483999934834 1.0343289534210807 1.113381822762877 0.9621961154052088 0.9533617012253933 0.9212553710208562 1.0 14.21015645237715 -4.760849734778761 24.954834508672022 0.9872980745642025 1.2014614304825997 0.6090764954727117 0.05175966724556571 10.525930987692224 445094.87861174165 0.0140845760708362 0.0814468000664163 1.73440399505765e-05 4.760849734778761 0.2141633559183972 RTDALTS(ph)SPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RTDALTSSPGR 11 1 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 RTDALT(0.02)S(0.49)S(0.49)PGR;RTDALT(0.07)S(0.465)S(0.465)PGR 89.44 0.013634 87331400.0 58489.0 76857.0 76081.0 57296.0 69221.0 61822.0 60820.0 39937.0 52062.0 42138.0 True False 68390.03248959275 84486.85502978228 77895.05957879922 54085.890876138306 55657.641957106294 58579.94548858891 55058.68930133172 38888.696066749246 52823.30825837262 49777.28583577551 1.3739204808238066 1.6972973437828665 1.564871572865372 1.0865576531146692 1.1181333217068357 1.1768408924876903 1.106100671759817 0.7812538472879028 1.06119301949581 1.0 15.603199947393122 -5.777584252785648 5.613533649872537 1.0462387027122213 1.5637188935832047 0.7733243767458133 0.12361406172080969 0.07678638651756806 7.47625742577938 0.03654551573947271 0.05800309757800951 1.6688440213860924e-06 5.777584252785648 0.5174801908709834 RTDALTS(ph)SPGR ddPTM_PC-9_Lapatinib_30min_R1 1 RTDALTSSPGR 11 1 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 RT(0.001)DALT(0.199)S(0.4)S(0.4)PGR 82.925 0.006144600000000001 28354000.0 37557.0 49107.0 45571.0 35048.0 44687.0 44380.0 42198.0 50521.0 51382.0 34180.0 True False 37021.43029288971 48993.29575862509 41824.32828914709 37625.54683670063 42058.59851802231 42481.9708548329 44382.80596360023 52868.39009597808 45594.81808355304 40087.96745801283 0.9235047980834914 1.2221446699671041 1.0433137657316471 0.9385745704395895 1.049157669619281 1.0597187522497242 1.107135352025161 1.3188094445384682 1.137369165231636 1.0 15.290881651301495 -7.526100834974349 24.973566935654617 1.1794480688208568 1.0470536340239598 0.1750029038465466 0.10548058984441447 141.32312266825997 1095322.243774808 0.04798545711864173 0.027885829642478224 2.9778249544588806e-08 7.526100834974349 -0.13239443479689705 RTDALTSS(ph)PGR ddPTM_PC-9_AZD4547_30min_R2 4 RTDALTSSPGR 11 1 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 RTDALT(0.005)S(0.14)S(0.855)PGR;RT(0.001)DALT(0.01)S(0.062)S(0.927)PGR;RTDALT(0.005)S(0.305)S(0.69)PGR;RTDALT(0.011)S(0.096)S(0.893)PGR 124.39 0.00075528 357369000.0 96789.0 122664.0 140507.0 122044.0 131890.0 145252.0 140626.0 164602.0 133122.0 116797.0 True False 127565.88866373437 162312.7391747416 138643.78537435728 93908.6413610037 113579.35008711561 136169.36947813132 153141.44157134066 139166.5430776722 140158.5571460508 112707.9725802401 1.1318266644617043 1.440117637278822 1.2301151568994173 0.8332031817371872 1.0077312854355105 1.2081609344998943 1.3587454202702014 1.234753317726441 1.2435549494625842 1.0 16.782230044917306 -6.982816132599923 24.72957873168158 1.2366300844334455 1.1324154851901886 0.04468972156173745 0.16740901029662414 650.788639654845 936556.3816859953 0.06440765674702922 0.05678801152303296 1.0403605303895932e-07 6.982816132599923 -0.10421459924325682 RTDALTSS(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RTDALTSSPGR 11 1 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 RTDALT(0.001)S(0.024)S(0.975)PGR;RTDALT(0.002)S(0.121)S(0.877)PGR;RTDALT(0.002)S(0.112)S(0.886)PGR 124.81 0.00022585 227819000.0 94403.0 133654.0 144880.0 110301.0 127822.0 86834.0 122913.0 70360.0 80987.0 87092.0 True False 110383.56335575941 146922.28583148582 148334.48866045967 104121.19257066703 102776.19667790437 82280.27217747939 111269.79082694183 68513.1245525823 82171.28166264898 102881.0901801073 1.0729237332391988 1.428078625277769 1.4418051791712163 1.0120537446520907 0.998980439437225 0.7997608893280254 1.0815378281096066 0.6659447759801221 0.7987015059696296 1.0 16.650618309823216 -5.9477307103666215 3.3019587452948516 0.8835199303576047 1.3243660660044951 0.6150644279956694 0.14861616528618432 0.15544790773605652 3.4782800182421676 0.04448825319000154 0.06772456750532915 1.1278966055533688e-06 5.9477307103666215 0.44084613564689046 RTDALTSS(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 3 RTDALTSSPGR 11 1 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 RTDALT(0.006)S(0.222)S(0.772)PGR;RTDALT(0.004)S(0.031)S(0.965)PGR;RTDALT(0.133)S(0.133)S(0.735)PGR 90.697 0.003942800000000001 33931300.0 79052.9 88289.1 74208.7 67405.8 82102.7 86584.0 84961.3 85839.6 81096.4 63153.3 True False 77925.59114947345 88084.672013416 68107.547139866 72363.04739115718 77273.58060611886 82881.00415716208 89360.18039516635 89828.0211888665 71962.46944904927 74069.26375851734 1.0520638007626026 1.1892202992673464 0.9195115987909926 0.9769645831377126 1.043261086785584 1.1189662209600602 1.2064407807062978 1.212757041594558 0.9715564297177748 1.0 16.17658737657019 -6.7483367652455 5.679615651470394 1.1221354667927546 1.0343687927918026 0.08599104689681303 0.09680490357082484 0.3371837038338562 34.79112798469097 0.034077417487389086 0.032493529398709024 1.7851028146211628e-07 6.7483367652455 -0.08776667400095195 RTDEAAFQK ddPTM_PC-9_AZD4547_30min_R2 2 RTDEAAFQK 9 1 P26447 P26447 S100A4 Protein S100-A4 0 ; 121.6 0.0010167 11908200.0 33198.0 36611.0 69270.0 116727.0 81234.0 43658.0 45544.0 76134.0 38334.0 48251.0 False True 43754.27343870334 48444.78978287403 68351.43453978612 89817.39356417266 69956.06130090801 40928.05835841338 49597.327769581214 64369.23968527394 40360.25697958794 46561.74717646139 0.9397042871454505 1.0404418373579545 1.4679740062318836 1.9289953451226705 1.50243634620896 0.879006069151631 1.065194731237543 1.3824489755791396 0.8668114799607751 1.0 15.506857574297443 -6.7532708872161615 24.9996639264886 1.064251707947235 1.3931148304460528 0.25578064736930983 0.285194643589933 304.8840438577517 933096.1287896014 0.1057702421546447 0.1040330011938263 1.7649366141962725e-07 6.7532708872161615 0.3288631224988179 RTDEAAFQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RTDEAAFQK 9 1 P26447 P26447 S100A4 Protein S100-A4 0 ;;; 113.44 0.0013292999999999998 5811200.0 80047.0 88007.0 120710.0 103742.0 111420.0 92119.0 89160.0 83706.0 91322.0 67526.0 False True 93597.37609968393 96743.75334199934 123588.18419522414 97929.67207610192 89588.05083516217 87288.1174737687 80714.11933749988 81508.80619383807 92657.41148574965 79767.92926447828 1.1733710146762464 1.2128151530828395 1.5493467780197172 1.2276822650291777 1.1231086435517754 1.094275835898366 1.0118617855790693 1.0218242713006596 1.1615872737342225 1.0 16.283521206311065 -6.276147387419172 2.7337050793839706 1.061077686970994 1.3104739041620213 0.5351525214554433 0.1037144342709272 0.22389978752543543 3.337873567314943 0.03507207027394099 0.043654371210170205 5.294837214081546e-07 6.276147387419172 0.24939621719102734 RTDEAAFQK ddPTM_PC-9_Lapatinib_30min_R1 4 RTDEAAFQK 9 1 P26447 P26447 S100A4 Protein S100-A4 0 ;;; 173.24 0.0017324000000000003 26727100.0 85659.0 71686.8 81784.0 79811.0 71140.0 73218.0 74448.0 63910.0 71740.0 56429.6 False True 84437.48695206326 71520.81361902396 75060.03521536967 85680.56718169135 66955.68506662133 70086.6368194943 78302.5531631384 66879.49191492569 63659.88574430913 66183.38117228438 1.2758110186643525 1.080646113151057 1.1341220996246497 1.2945933807560108 1.0116691513890252 1.058976371077948 1.183115032447589 1.0105179084282387 0.9618711618645435 1.0 16.014181377393335 -7.199733577725168 0.5002770885139851 0.9757791559925163 1.1927015346489394 0.41650055427765986 0.08498636998381438 1.0521834878635554 0.5686048770459846 0.08391678490751175 0.07907587139905746 6.313445302958884e-08 7.199733577725168 0.21692237865642305 RTEEENLR ddPTM_PC-9_AZD4547_30min_R2 1 RTEEENLR 8 1 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;A0A087X1Q1;A0A087WXZ1;A0A087WT22 J3KP33 TP53 Cellular tumor antigen p53 0 78.516 0.013932 3656800.0 8417.9 10942.0 8885.1 18850.0 13036.0 13359.0 8143.1 12987.0 10731.0 10193.0 False True 11094.617096802844 14478.787517527733 8767.277768578791 14504.423729596869 11226.176417739338 12523.65961816951 8867.82012472503 10980.15756157109 11298.218752229299 9836.14617250774 1.127943495574777 1.471998002428663 0.8913326027101487 1.4746043292989153 1.1413185836051079 1.2732282947536335 0.901554325159461 1.1163068715124311 1.148642827595231 1.0 13.263877459285498 -7.23707864140789 24.84478225215481 1.0513182181331826 1.2327513481497145 0.22504695839409428 0.17089178343691877 1095.4858229714519 1117254.5536896558 0.061388733900263864 0.04752691831469209 5.7932378382726127e-08 7.23707864140789 0.18143313001653194 RTEEENLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RTEEENLR 8 1 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;A0A087X1Q1;A0A087WXZ1;A0A087WT22 J3KP33 TP53 Cellular tumor antigen p53 0 ;; 109.48 0.0023902 12190000.0 48819.0 50639.0 62290.0 61294.0 65418.0 61668.0 59002.0 57816.0 59674.0 43188.0 False True 57083.09248079854 55666.10525850789 63775.229836140534 57859.89589782916 52599.81250704232 58434.02151969047 53412.903422511896 56298.391261115605 60546.61935788341 51017.642523980096 1.1188892637280814 1.0911148086143505 1.2500622663260836 1.1341154360598487 1.031012212732459 1.1453689082600085 1.0469496585892997 1.103508286072869 1.186778070535587 1.0 15.638708614484681 -6.01294751077733 24.928950940516323 1.0909911744480993 1.1546242865459226 0.19163495446174006 0.06365856101319928 1049.5712391272652 2020835.6911518697 0.01820823821108145 0.024704501520244317 9.706272710437817e-07 6.01294751077733 0.0636331120978233 RTEEENLR ddPTM_PC-9_Lapatinib_30min_R1 1 RTEEENLR 8 1 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;A0A087X1Q1;A0A087WXZ1;A0A087WT22 J3KP33 TP53 Cellular tumor antigen p53 0 117.81 0.0022339 2997200.0 16523.0 14361.0 13356.0 13531.0 13821.0 14427.0 12331.0 12157.0 16232.0 9479.0 False True 16287.378990052903 14327.747986837212 12257.921235650932 14526.114878092796 13008.075953131482 13809.990840979588 12969.438843953618 12721.858601310456 14403.781229462315 11117.432520026434 1.4650306139221951 1.2887641063732893 1.1025856206970517 1.306606975299928 1.1700611566294044 1.2421924591044653 1.166585794030327 1.144316241937505 1.295603207261749 1.0 13.440536027475328 -2.079585587828504 0.025260873353343954 2.0974223266655395e-06 2.826442915805724 0.4538954087076713 0.09102034649264139 1767.365814957724 3.7774562212456075 149.62445013464372 295.4422332239498 0.008325578349317438 2.079585587828504 2.8264408183833973 RTEEGPTLSYGR ddPTM_PC-9_AZD4547_30min_R2 1 RTEEGPTLSYGR 12 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 0 88.163 0.005179 2875400.0 7501.4 7567.7 12935.0 20215.0 16477.0 14149.0 11795.0 15039.0 9426.5 10687.0 False True 9886.689161187094 10013.811030560648 12763.473448421146 15554.744068636648 14189.45296372284 13264.260793283958 12844.732150057305 12715.068111840119 9924.76554541884 10312.851382869629 0.9586765865364433 0.9710031356792644 1.2376279822690137 1.5082874261597692 1.3759000723400823 1.2861875247535157 1.2455073454654169 1.2329342913794668 0.9623687161733537 1.0 13.332155655726044 -8.258171594430731 22.65113509156384 0.9811842702576874 1.2357629118960478 0.2824070162071818 0.15624971838446733 103.85544870935605 719944.1741205954 0.13268768378638154 0.045199323558196565 5.518593506215001e-09 8.258171594430731 0.2545786416383604 RTEEGPTLSYGR ddPTM_PC-9_Lapatinib_30min_R1 1 RTEEGPTLSYGR 12 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 0 64.22399999999999 0.028162 4465200.0 13416.0 11271.0 13470.0 12346.0 11246.0 15136.0 13003.0 14027.0 17379.0 12030.0 False True 13224.68537980692 11244.902691988174 12362.548595703654 13253.966025048676 10584.532390486693 14488.668563739313 13676.231715832357 14678.745628081086 15421.594011016852 14109.369471032604 0.9372981129282926 0.7969812340001902 0.8761942637539346 0.9393733754197788 0.7501775619539472 1.0268827812245922 0.9693014095286465 1.0403544721270108 1.0930037690683716 1.0 13.784365896801432 -6.7897607491186704 24.995127186195862 1.0248928094079348 0.8618123707249078 0.6491517271269929 0.06097396600153615 134.9059092695695 119060.73920084348 0.020972622429760092 0.018499604823608098 1.6227037914076545e-07 6.7897607491186704 -0.16308043868302702 RTES(ph)VPSDINNPVDR ddPTM_PC-9_AZD4547_30min_R2 1 RTESVPSDINNPVDR 15 1 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;A8MY87 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 RT(0.473)ES(0.525)VPS(0.002)DINNPVDR 102.07 0.00071146 11564000.0 5060.3 21902.0 19565.0 23925.0 26209.0 23275.0 18378.0 22181.0 22272.0 23980.0 True False 6669.370139221353 28981.39318304628 19305.555316456088 18409.46088756526 22570.332750270798 21819.61057061869 20013.606397096504 18753.436118673177 23449.25245081084 23140.46749894395 0.2882124200613371 1.2524117407899769 0.8342768060903317 0.7955526779398645 0.975362003870528 0.9429200413351398 0.8648747653006515 0.810417340078761 1.0133439374930944 1.0 14.498130390563352 -4.742008009355832 24.999966614425293 0.9278400268622572 0.2882102565841004 0.7002843474898788 0.12820195044078583 774.6080774222152 996541.9793602575 0.031029149217400825 1.1703418552476237 1.811306687789095e-05 4.742008009355832 -0.6396297702781568 RTES(ph)VPSDINNPVDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RTESVPSDINNPVDR 15 1 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;A8MY87 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 RT(0.005)ES(0.995)VPSDINNPVDR;RT(0.38)ES(0.619)VPS(0.001)DINNPVDR 142.84 4.3278e-05 24496700.0 34199.0 29183.0 40220.0 39247.0 43605.0 41675.0 36375.0 43466.0 39622.0 33715.0 True False 39988.21523896082 32080.09537627195 41178.99733519938 37048.11783049079 35060.91327111162 39489.48963535543 32929.2966678057 42325.06355603385 40201.396792540414 39827.262612206854 1.0040412676191468 0.8054808006423109 1.0339399354696857 0.9302200402579445 0.8803244554489071 0.991519051154977 0.8268029110721016 1.0627158579324865 1.0093939215450596 1.0 15.28146870405424 -7.786508695998939 24.999638049080097 1.0270411936250197 0.9253257129905097 0.289730885831183 0.07128024381589065 282.64278395322253 281853.05729523185 0.036282219893904906 0.01744042773603033 1.6349004147373543e-08 7.786508695998939 -0.10171548063450997 RTES(ph)VPSDINNPVDR ddPTM_PC-9_Lapatinib_30min_R1 3 RTESVPSDINNPVDR 15 1 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;A8MY87 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 RT(0.031)ES(0.969)VPSDINNPVDR;RT(0.107)ES(0.888)VPS(0.005)DINNPVDR;RT(0.029)ES(0.97)VPSDINNPVDR 142.4 4.4783999999999997e-07 20550700.0 34366.9 35407.1 37187.9 32802.3 32247.7 35106.9 32613.4 32996.8 38119.7 23904.7 True False 33876.82170388241 35325.11703535572 34130.45441144527 35214.69056726501 30350.95368741756 33605.45972518104 34301.962273408215 34529.95178874072 33826.257967763326 28036.595543989428 1.208307251525231 1.2599645695188133 1.217353738897955 1.2560259148445163 1.0825477594024175 1.1986284023840934 1.223471024489704 1.2316028789787694 1.2065037609395162 1.0 14.775023554504399 -11.161142123866629 2.1704979366339794 0.9656450223691186 1.2094944539976884 0.645142259142798 0.04658561109874722 916211.190282442 630999.9891421952 175373.95754888077 0.012993827769871097 6.9001395823545225e-12 11.161142123866629 0.24384943162856976 RTGAPAQADSR ddPTM_PC-9_AZD4547_30min_R2 1 RTGAPAQADSR 11 1 P20290 P20290 BTF3 Transcription factor BTF3 0 80.17 0.010419 207560.0 1103.3 1068.8 886.59 2225.4 2519.1 1963.1 652.13 2460.7 1162.2 2340.8 False True 1454.1264499343758 1414.2686984768457 874.8332373123844 1712.3684120872606 2169.3664478311707 1840.347046667308 710.1683066567934 2080.4553562607202 1223.631519321675 2258.84930448407 0.6437465514179149 0.6261013940457927 0.38729154511358593 0.7580711155401189 0.9603856457023202 0.8147276770584084 0.31439383992859965 0.921024413683012 0.5417056892164646 1.0 11.14137231151289 -14.522878745280336 0.2985149707901549 3.7053947266588487 0.6503347408410097 0.19676306063663895 0.20105295708815238 469.90172583607625 4.356576105773189 795.8618052108501 0.20833066199562011 3.0000000000000132e-15 14.522878745280336 -3.055059985817839 RTGGPAYGPSSDVSTAS(ph)ETESEKR ddPTM_PC-9_AZD4547_30min_R2 2 RTGGPAYGPSSDVSTASETESEKR 24 2 P51116 P51116 FXR2 Fragile X mental retardation syndrome-related protein 2 1 RTGGPAYGPSSDVST(0.002)AS(0.876)ET(0.079)ES(0.043)EKR;RTGGPAYGPSSDVS(0.024)T(0.04)AS(0.892)ET(0.032)ES(0.012)EKR 67.075 0.0084755 0.0 4162.8 5388.0 8902.0 8092.4 4570.4 4846.7 7309.799999999999 5058.0 6377.5 7315.0 True False 5486.483808381054 7129.565631917327 8783.953663536526 6226.822206333669 3935.878850846569 4543.635082819232 7960.358039041029 4276.40232127717 6714.601630075704 7058.904076512713 0.7772430038589677 1.0100102727900395 1.24437923625618 0.8821230801325587 0.5575764747877121 0.6436742918688177 1.12770452080908 0.6058167493033603 0.9512243766588901 1.0 12.785228501287614 -5.992248260229774 24.98580126804722 0.7943129151930254 1.0192842090373433 0.15622042603298003 0.2004203108658343 297.7507137083805 959713.2061350815 0.056333855818150286 0.08338285102585832 1.018009286555323e-06 5.992248260229774 0.2249712938443179 RTGGPAYGPSSDVSTAS(ph)ETESEKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTGGPAYGPSSDVSTASETESEKR 24 2 P51116 P51116 FXR2 Fragile X mental retardation syndrome-related protein 2 1 RTGGPAYGPS(0.002)S(0.005)DVS(0.039)T(0.146)AS(0.698)ET(0.055)ES(0.055)EKR 42.348 0.025491 3731200.0 10946.0 12253.0 12922.0 9563.1 11714.0 8140.5 13093.0 9686.5 6643.4 12765.0 True False 12798.941606645372 13469.396862744072 13230.109486957892 9027.310510988518 9418.725789652599 7713.597849468774 11852.73625488879 9432.239638695113 6740.547156921987 15079.193452315596 0.8487815775504848 0.8932438532165445 0.8773751413691324 0.5986600370593603 0.6246173457113011 0.5115391531955084 0.7860325084607663 0.6255135374794649 0.4470097938750758 1.0 13.880271644133279 -5.755832978077291 24.95673714547949 0.6386591463000476 0.8751446324396479 0.31710321618146053 0.1442818698901611 140.3337918216221 624683.2521391186 0.037328099746360206 0.06240911777063328 1.7545551427642897e-06 5.755832978077291 0.2364854861396003 RTGNFIPLNEEGCR ddPTM_PC-9_Lapatinib_30min_R1 1 RTGNFIPLNEEGCR 14 1 O00322;O00322-2 O00322 UPK1A Uroplakin-1a 0 68.171 0.020646 50982000.0 59220.0 41828.0 58106.0 43836.0 42835.0 36859.0 40563.0 41784.0 55901.0 28681.0 False True 58375.51194038209 41731.14983590467 53328.74897564638 47059.8456726092 40315.5295168502 35282.62649252562 42663.153663716716 43725.43717999144 49604.840716373394 33638.47263496974 1.73537938460667 1.2405780217417475 1.5853498924980056 1.3989887764311548 1.1984946508819534 1.048877185221741 1.26828450645423 1.2998639282609858 1.474646047538003 1.0 15.037824580624676 -6.099837158066138 3.923721124475191 1.2253022443144643 1.4930772023626386 0.3992956722471718 0.16854637113533838 0.2692269864735209 7.398841732157829 0.05024604011660377 0.06751173107895989 7.946261298269048e-07 6.099837158066138 0.2677749580481743 RTGS(ph)NAAQYK ddPTM_PC-9_Lapatinib_30min_R1 1 RTGSNAAQYK 10 1 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 RT(0.14)GS(0.86)NAAQYK 105.66 0.0035674 7644400.0 35043.0 20199.0 26701.0 24748.0 23442.0 24248.0 18013.0 19035.0 27455.0 18068.0 True False 34543.28039390085 20152.230456522866 24505.746848840638 26568.050476907865 22063.187648745243 23210.96956484876 18945.625001714103 19919.43559068392 24362.72878603301 21191.02972590332 1.6300897521594298 0.9509792925206152 1.1564207669854523 1.2537404184956535 1.0411569392390507 1.0953205136830289 0.8940398483116421 0.9399937543542284 1.1496717762729902 1.0 14.371166073175509 -4.7549352746136835 24.999453743306177 1.0570200581848115 1.6300907130907343 0.7246880492941572 0.10660020254006497 124.77167230069254 479533.4931463534 0.028242813859407346 0.26247740606259273 1.7581856268762014e-05 4.7549352746136835 0.5730706549059228 RTGS(ph)NISGASSDISLDEQYK ddPTM_PC-9_AZD4547_30min_R2 1 RTGSNISGASSDISLDEQYK 20 1 P22059 P22059 OSBP Oxysterol-binding protein 1 1 RT(0.394)GS(0.587)NIS(0.018)GAS(0.001)SDISLDEQYK 110.06 3.4635e-05 7885300.0 19378.0 25294.0 37176.0 36379.0 43996.0 48586.0 47997.0 55172.0 52771.0 41498.0 True False 25539.80091256078 33469.790848871 36683.02194963312 27992.38359994719 37887.91482623963 45547.90973938044 52268.64001749055 46646.43512643414 55560.36732586826 40045.167651008174 0.6377748530144508 0.8358009920337633 0.9160411630517818 0.6990202624171672 0.9461295094686852 1.1374133862124993 1.305242132409318 1.1648455447347783 1.3874424951862945 1.0 15.289340539123513 -6.685731221993033 2.3753657606831164 1.227671638933057 0.786982235230529 0.7440954855196087 0.11841692568489569 0.14106500114324388 1.627891106746087 0.04241582260143514 0.04108712475102606 2.0619055993419326e-07 6.685731221993033 -0.44068940370252807 RTGS(ph)NISGASSDISLDEQYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RTGSNISGASSDISLDEQYK 20 1 P22059 P22059 OSBP Oxysterol-binding protein 1 1 RT(0.148)GS(0.589)NIS(0.204)GAS(0.051)S(0.008)DISLDEQYK;RT(0.318)GS(0.566)NIS(0.116)GASSDISLDEQYK 144.73 0.0001056 12763300.0 32504.0 37923.0 48163.0 59287.0 68087.0 47370.0 56225.0 54034.0 49217.0 40786.0 True False 38006.28521673684 41687.74481562422 49311.38857919466 55965.34160104741 54745.84111661911 44885.83380988091 50898.960966250845 52615.664753755394 49936.705515583795 48180.17893820164 0.7888365310034577 0.865246782688272 1.0234787347395278 1.161584345148062 1.1362730965951562 0.9316244729487986 1.0564294713711306 1.0920603848574937 1.0364574523402075 1.0 15.556152131215844 -5.210008883445445 2.9046760950262556 1.0627500388632232 0.8027547801518509 0.6900845914454518 0.0621904607508316 0.15411618872023278 2.523818603548523 0.017537929401050697 0.05802706452289582 6.165823896081181e-06 5.210008883445445 -0.2599952587113723 RTGT(ph)PSDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTGTPSDPR 9 1 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 RT(0.115)GT(0.88)PS(0.005)DPR 96.06700000000001 0.017811 65473000.0 25228.0 26783.0 42546.0 39080.0 57057.0 42436.0 45148.0 40357.0 34790.0 34376.0 True False 29498.60212428738 29441.8392373194 43560.45799660354 36890.47429906949 45877.09043710162 40210.581455691514 40871.254596785984 39297.671511776025 35298.737933786295 40608.09667973371 0.7264216876977948 0.7250238657950434 1.0727037600445644 0.9084512034635798 1.1297522954331791 0.9902109368193909 1.0064804297312366 0.9677299535042804 0.8692536912571636 1.0 15.309479788612736 -5.250977946049127 24.7903599360118 0.9941561292096518 0.7257227208079111 0.7026027973584927 0.06957221806520231 327.1712220527536 775290.1685602394 0.017448929144865535 0.04509737957956132 5.610764673884222e-06 5.250977946049127 -0.2684334084017407 RTILT(ph)T(ph)S(ph)NSFPY(ph)VK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTILTTSNSFPYVK 14 1 A0A0J9YW64;A6NIW2;Q5JSL3 A0A0J9YW64 DOCK11 Dedicator of cytokinesis protein 11 4 RT(0.5)ILT(0.75)T(0.75)S(0.935)NS(0.065)FPY(1)VK 87.49799999999999 0.0047199 0.0 21315.0 22209.0 27569.0 23420.0 29009.0 27510.0 30488.0 32390.0 27313.0 20814.0 True False 24923.208509560234 24413.762745832308 28226.34951601472 22107.85332866446 23324.894692848906 26067.327171412806 27599.955925994756 31539.79682004179 27712.400953880588 24587.413436466646 1.0136571939118881 0.992937415272125 1.1479999548936293 0.8991532755485111 0.9486518276157815 1.0601898910094885 1.12252376596312 1.2827618855289498 1.1270970419677875 1.0 14.585632352846336 -7.185694681390015 3.002807884024224 1.159286630569728 1.0033015532152463 0.3173618874997488 0.0883284795802857 0.27986173870843284 4.934408964864069 0.037710424380789885 0.0272641129999059 6.520866642779652e-08 7.185694681390015 -0.15598507735448175 RTIQEVLEEQS(ph)EDEDR ddPTM_PC-9_Lapatinib_30min_R1 2 RTIQEVLEEQSEDEDR 16 1 M0R0Q7;P18858-2;P18858;P18858-3 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 RTIQEVLEEQS(1)EDEDR;RTIQEVLEEQS(1)EDEDR 177.09 4.109700000000001e-06 6472400.0 21755.4 19801.0 23254.8 20617.6 22312.8 22970.5 21712.9 21761.7 23179.9 16228.7 True False 21445.16400654825 19755.152001069804 21342.88011012392 22133.887082297366 21000.40497265264 21988.105261850833 22837.087719964362 22772.828026991672 20569.135566831785 19033.809171616525 1.1266879799618654 1.037897975279113 1.121314179294742 1.162872175649618 1.1033211893270807 1.1552130770881004 1.199816994804137 1.1964409132014848 1.0806631180008235 1.0 14.21627669171678 -5.508082899870616 22.47641073372634 1.1397677364049563 1.0816212156271712 0.06244139616454458 0.059907927616903535 333.40939109545565 506478.093059561 0.015196197202649486 0.0298656045573868 3.1039670339127623e-06 5.508082899870616 -0.05814652077778515 RTLEGELHDLR ddPTM_PC-9_AZD4547_30min_R2 4 RTLEGELHDLR 11 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ;;; 139.32 4.3688e-05 18802600.0 84834.0 77574.0 125226.0 186064.0 149796.0 129697.0 98946.0 129267.0 102086.0 119584.0 False True 111809.44734318214 102648.27845774965 123565.42141878502 143169.81946014368 128999.4110671739 121587.02608711188 107752.00231619932 109291.75541014918 107482.05754730031 115397.40055853693 0.9689078506275819 0.889519850195238 1.0707816711703548 1.240667630008865 1.1178710303941133 1.0536374779554516 0.9337472230281358 0.9470902713680229 0.9314079608992453 1.0 16.81625120064251 -7.242785309717874 9.618237165047509 0.9486416676432534 1.0611024906445536 0.25089082698263 0.08758679305135811 0.5898280417203314 293.96041216853735 0.039117729918523345 0.02962823008997314 5.7176121277062436e-08 7.242785309717874 0.11246082300130023 RTLEGELHDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RTLEGELHDLR 11 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ;;; 115.29 0.00054533 15694600.0 65938.1 48508.3 71104.3 88381.0 96806.0 85401.9 87364.9 80356.8 78271.8 63151.5 False True 77100.11799316118 53323.88344381364 72799.6961765594 83429.29910506809 77837.55922768546 80923.27402254741 79089.0642048983 78247.51914506745 79416.37699930258 74600.36704300102 1.033508561006399 0.7147938483074322 0.9758624395855361 1.1183497134401217 1.0433937836099179 1.0847570491965777 1.0601699071977744 1.048889197823439 1.064557456580951 1.0 16.18689510828485 -5.517356471158242 19.16171259117299 1.0612224763431473 0.8669450987443784 0.4839586190968659 0.07677316001328353 7.564502284415179 26245.05163432415 0.01874969786969644 0.034168927323976216 3.038390075584522e-06 5.517356471158242 -0.19427737759876884 RTLEGELHDLR ddPTM_PC-9_Lapatinib_30min_R1 1 RTLEGELHDLR 11 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 87.001 0.0042103999999999996 3822500.0 13770.0 12377.0 14250.0 12477.0 14196.0 15520.0 10796.0 12422.0 16216.0 12192.0 False True 13573.637274891273 12348.341816940607 13078.420006590719 13394.600202051852 13361.019190409846 14856.245778887047 11354.964054766298 12999.171468740513 14389.583317949773 14299.370955181163 0.9492471604125403 0.8635583939772099 0.9146150587730539 0.9367265346171413 0.9343781088194429 1.0389440084778072 0.7940883616738398 0.9090729591870933 1.006308834357215 1.0 13.803664062231315 -8.263319965212828 24.511831335070525 1.003154434222261 0.9168067394463557 0.2525978265468388 0.058868622729676495 181.92027238938294 2371046.2929911492 0.04829014439625424 0.014940248053229676 5.4535592363511465e-09 8.263319965212828 -0.0863476947759052 RTNS(ph)TGGSSGSSVGGGSGK ddPTM_PC-9_AZD4547_30min_R2 1 RTNSTGGSSGSSVGGGSGK 19 1 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 RT(0.046)NS(0.478)T(0.443)GGS(0.023)S(0.007)GS(0.002)S(0.001)VGGGSGK 88.571 0.00050808 37178000.0 11054.0 8132.2 10799.0 11979.0 11130.0 12456.0 11386.0 11576.0 13135.0 16717.0 True False 14568.942062516619 10760.774616161498 10655.798204058743 9217.426623705092 9584.791617784505 11677.124350918437 12399.331942395303 9787.19519001671 13829.289284366032 16131.742918258791 0.9031226282453765 0.6670559201623442 0.660548476259061 0.5713844232709848 0.5941572256855093 0.7238600571610664 0.7686294038544998 0.6067041385180411 0.8572718617225968 1.0 13.977614699238726 -8.496557210735197 4.018129715884607 0.9992092144205041 0.6831220143176202 0.5483442007507379 0.09212793835710406 0.1375145112361923 5.602294403272352 0.09066193667268836 0.023770186950261844 3.187445657578772e-09 8.496557210735197 -0.31608720010288394 RTNST(ph)GGSSGSSVGGGSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTNSTGGSSGSSVGGGSGK 19 1 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 RT(0.083)NS(0.302)T(0.612)GGS(0.002)S(0.001)GS(0.001)SVGGGSGK 103.51 0.00024274 5806900.0 14708.0 16297.0 18680.0 23197.0 29237.0 28632.0 25376.0 23378.0 23107.0 18085.0 True False 17197.773903758458 17914.858456879156 19125.402044294508 21897.347295688713 23508.219729560606 27130.48751624467 22972.201573669758 22764.35227103849 23444.896160850818 21363.667339218762 0.8050010155413398 0.8385666268071685 0.8952302870389993 1.0249807276997913 1.100383157830067 1.269935872219811 1.0752929826564983 1.0655638804695482 1.0974190801881378 1.0 14.382871704381934 -5.774137006711244 1.8908451486817563 1.1112989425523063 0.8214041747069438 0.7602251922262735 0.06479829181943035 0.16267572672924252 1.186740478600858 0.020961594634528524 0.0418438929274937 1.6821433122610282e-06 5.774137006711244 -0.2898947678453625 RTNSTGGS(ph)SGSSVGGGSGK ddPTM_PC-9_AZD4547_30min_R2 1 RTNSTGGSSGSSVGGGSGK 19 1 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 RT(0.022)NS(0.062)T(0.057)GGS(0.418)S(0.418)GS(0.017)S(0.007)VGGGSGK 54.537 0.015102 37581000.0 5452.4 4072.3 7346.1 11006.0 9670.1 7816.8 6903.1 7941.6 7212.9 6935.1 True False 7186.149783034698 5388.5913368331385 7248.685914143529 8468.736741004943 8327.573533076184 7328.01426029698 7517.462526923328 6714.408199813121 7594.159168572804 6692.304259880154 1.0737930470548254 0.8051922219283015 1.083137531208621 1.265444070105175 1.2443507063776735 1.0949911982077472 1.123299574406671 1.0033028892702143 1.1347599980023624 1.0 12.708287322423551 -5.502999002836863 23.708198281398783 1.1312681222098007 0.9406605988756035 0.33969339290376455 0.10092814902840433 401.0497576204282 478281.94408433273 0.026826962116621347 0.05454029982966317 3.1405159046588226e-06 5.502999002836863 -0.19060752333419717 RTPALIALR ddPTM_PC-9_Lapatinib_30min_R1 2 RTPALIALR 9 1 A0A0A0MSS8;P42330;S4R3Z2;B4DK69;P52895;H0Y804;Q04828;P42330-2 A0A0A0MSS8;B4DK69;Q04828;P42330-2 AKR1C3;AKR1C2;AKR1C1 Aldo-keto reductase family 1 member C3;Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 ; 170.5 0.00033644 10638100.0 42700.0 41568.0 46303.0 46616.0 45717.0 45807.0 44288.0 41031.0 47431.0 40833.0 False True 42091.09016977904 41471.75184993029 42496.1460747488 50044.29614641737 43028.015943080216 43847.941391332395 46581.015937151744 42937.45005102979 42088.82130942749 47890.929643447525 0.878894823782941 0.8659625561393647 0.8873527073108959 1.0449639737420398 0.8984585653990816 0.9155792488845893 0.9726479791466106 0.8965674788671496 0.8788474482074732 1.0 15.547464820531049 -5.546012712379958 24.999729994070513 0.9398755419012141 0.8734858207040448 0.281855143268262 0.04870740269870951 293.91151942800354 317614.158967602 0.013203003753978194 0.022869810724818796 2.8443778474880007e-06 5.546012712379958 -0.06638972119716935 RTPAPPEPGS(ph)PAPGEGPSGR ddPTM_PC-9_AZD4547_30min_R2 2 RTPAPPEPGSPAPGEGPSGR 20 1 P0C1Z6-2;P0C1Z6 P0C1Z6-2 TFPT TCF3 fusion partner 1 RTPAPPEPGS(0.987)PAPGEGPS(0.013)GR;RTPAPPEPGS(0.999)PAPGEGPS(0.001)GR 107.09 0.0001751 51281400.0 25325.9 25020.9 32435.1 53651.0 46484.1 37732.0 31839.0 37260.0 28002.3 34616.3 True False 33379.00938855522 33108.416614632566 32004.989381282125 41282.5908496871 40030.58508897186 35372.61207521312 34672.60931968417 31502.32314962185 29482.444410171513 33404.39387338168 0.9992400854533484 0.9911395710435277 0.9581071730442421 1.2358431350728134 1.198362863301952 1.0589209374458912 1.0379655278616824 0.9430592654676037 0.8825918087879038 1.0 15.02775026076422 -7.671245406917628 2.866737611432266 0.9312910974438039 1.0764685157508362 0.3151840013353916 0.08656650009301937 0.34724549520704406 5.713385279199826 0.05566789765115843 0.02755256943366641 2.1318399332769676e-08 7.671245406917628 0.14517741830703235 RTPAPPEPGS(ph)PAPGEGPSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RTPAPPEPGSPAPGEGPSGR 20 1 P0C1Z6-2;P0C1Z6 P0C1Z6-2 TFPT TCF3 fusion partner 1 RT(0.014)PAPPEPGS(0.985)PAPGEGPS(0.001)GR;RTPAPPEPGS(0.997)PAPGEGPS(0.003)GR;RTPAPPEPGS(0.999)PAPGEGPS(0.001)GR;RTPAPPEPGS(1)PAPGEGPSGR 118.04 7.034e-06 84397700.0 101111.0 82986.9 95536.0 138567.0 148066.0 138360.0 138039.0 168576.0 141225.0 91425.0 True False 118227.09526672027 91225.29099068465 97813.94056229763 130803.54023027506 119053.53020067436 131104.1580311405 124962.94660418498 164151.05862103618 143290.14845354896 107999.62878009843 1.0946990892667448 0.844681523641451 0.9056877478853173 1.2111480540049673 1.102351290883445 1.2139315617286608 1.1570682975089306 1.5199224337638189 1.3267651942147571 1.0 16.720666827954894 -6.242326369843774 0.9665208465159529 1.2856239597179175 0.9363815282564043 0.3738741713482212 0.14912448001902562 0.534553013700775 1.0558680284132085 0.07011198327092029 0.11325230915062716 5.723657397132215e-07 6.242326369843774 -0.34924243146151324 RTPAPPEPGS(ph)PAPGEGPSGR ddPTM_PC-9_Lapatinib_30min_R1 3 RTPAPPEPGSPAPGEGPSGR 20 1 P0C1Z6-2;P0C1Z6 P0C1Z6-2 TFPT TCF3 fusion partner 1 RT(0.003)PAPPEPGS(0.997)PAPGEGPS(0.001)GR;RTPAPPEPGS(0.998)PAPGEGPS(0.002)GR;RTPAPPEPGS(0.98)PAPGEGPS(0.02)GR 131.26 1.7939000000000002e-05 86000000.0 76722.0 53902.4 65151.0 51749.4 56746.0 59203.0 43789.2 47915.0 60710.0 41614.2 True False 75627.9302109082 53777.59230455362 59794.53627013282 55555.223506937735 53408.31184692848 56671.02569893363 46056.390513798855 50141.305822307346 53872.20049535833 48807.159022563974 1.5495253509007716 1.1018382012296961 1.225118147984997 1.1382597270464785 1.0942720886957864 1.1611211722594654 0.9436400609284917 1.0273350636763467 1.1037766092972703 1.0 15.57480515702692 -1.5228787452803376 0.8577095973067188 1.0673279343339779 166.53281673902993 0.7457820663598005 0.07985036519253715 363.02812686450625 0.9762135898292839 0.02764024643337709 117268.30488705556 0.029999999999999995 1.5228787452803376 165.46548880469595 RTPHVQAVQGPLGS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTPHVQAVQGPLGSPPK 17 1 Q15149 Q15149 PLEC Plectin 1 RTPHVQAVQGPLGS(1)PPK 66.64399999999999 0.0091017 6286400.0 9528.2 12359.0 8631.6 13910.0 16483.0 13283.0 12850.0 11933.0 13578.0 11926.0 True False 11141.136069471808 13585.919842214476 8837.410079525293 13130.667796828458 13253.274474205546 12586.416096614905 11632.754974056435 11619.771394058622 13776.552562947698 14088.089393835948 0.7908195183902269 0.9643550280252204 0.6272965646705778 0.9320403519425142 0.9407432124901434 0.8934083071705891 0.8257155849072189 0.824793985133477 0.9778865095060684 1.0 13.782188348262968 -14.522878705094804 0.10730279825483006 1.4706246296240535 0.776034100301093 0.2100801542828643 0.09548817069671534 297.2050822924661 2.1259664838161343 30.374278212471722 1.2959467034439138 3.0000002775918425e-15 14.522878705094804 -0.6945905293229605 RTPHVQAVQGPLGS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 1 RTPHVQAVQGPLGSPPK 17 1 Q15149 Q15149 PLEC Plectin 1 RTPHVQAVQGPLGS(1)PPK 59.339 0.017965000000000002 106550000.0 70682.0 51912.0 61022.0 59651.0 86904.0 55982.0 61751.0 58885.0 62819.0 50389.0 True False 69674.06171850883 51791.80095346376 56005.00671173185 64037.93352990266 81792.4775798377 53587.780360415876 64948.1646300365 61621.012070261255 55743.6627066038 59098.671510877946 1.1789446350868367 0.8763615091403661 0.947652549201945 1.0835765321410917 1.3839985821810332 0.9067510147085504 1.098978419812396 1.0426801566752484 0.9432303854130357 1.0 15.850838079728739 -10.310452718572844 5.2180469405102645 0.9999999760634646 1.050780003440943 0.011469992722826117 0.14293126112771856 4.02209217650035e-08 9.185367349969829e-09 0.13984803140142468 0.03391811353262338 4.892685286596318e-11 10.310452718572844 0.05078002737747833 RTPHVQAVQGPLGS(ph)PPKR ddPTM_PC-9_AZD4547_30min_R2 1 RTPHVQAVQGPLGSPPKR 18 2 Q15149 Q15149 PLEC Plectin 1 RTPHVQAVQGPLGS(1)PPKR 53.278 0.015758 68629000.0 64750.0 72000.0 74013.0 102350.0 79985.0 67086.0 64257.0 81321.0 72934.0 91101.0 True False 85339.15311633359 95272.59196326064 73031.53926076496 78754.78879173688 68880.46339159872 62891.10181484544 69975.74851769673 68754.70802067636 76789.142342288 87911.58171898632 0.9707384561584204 1.0837319736528477 0.8307385424393097 0.8958408807098981 0.7835197825444491 0.715390402323552 0.7959787225917245 0.7820893069636053 0.8734815236034345 1.0 16.423765622140657 -5.27395456211699 22.961313982535444 0.8215691307585565 1.0272351961069175 0.48550931430223476 0.07839120835672311 168.6069633895983 309340.77949917986 0.020151126358658455 0.04252177683649404 5.321639337887715e-06 5.27395456211699 0.20566606534836096 RTPS(ph)DDEEDNLFAPPK ddPTM_PC-9_AZD4547_30min_R2 4 RTPSDDEEDNLFAPPK 16 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 RT(0.111)PS(0.889)DDEEDNLFAPPK;RT(0.366)PS(0.634)DDEEDNLFAPPK;RT(0.005)PS(0.995)DDEEDNLFAPPK;RT(0.46)PS(0.54)DDEEDNLFAPPK 171.04 1.3892e-05 200473000.0 227472.0 229295.0 292203.0 344722.0 339123.0 312265.0 260757.0 317163.0 262496.0 298948.0 True False 299803.3642884735 303410.1246418861 288328.19729795144 265251.6688018087 292041.6251390781 292739.0201862186 283963.86784675624 268152.7460306908 276371.0026637951 288481.92151268956 1.0392448951962694 1.0517474476421909 0.999467127042374 0.9194741473258696 1.0123394339850582 1.0147568993273701 0.9843385206177138 0.9295305044579559 0.9580184477925361 1.0 18.138121385816362 -5.416225130869433 4.391162625767809 0.9738984207935333 1.0444402789962604 0.4600495382426051 0.030489669445631133 0.20580094880360808 6.513238133392976 0.008667619649043713 0.018844840770062102 3.835083897315793e-06 5.416225130869433 0.07054185820272707 RTPS(ph)DDEEDNLFAPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 RTPSDDEEDNLFAPPK 16 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 RT(0.027)PS(0.973)DDEEDNLFAPPK;RT(0.237)PS(0.763)DDEEDNLFAPPK;RT(0.232)PS(0.768)DDEEDNLFAPPK;RT(0.232)PS(0.768)DDEEDNLFAPPK;RT(0.002)PS(0.998)DDEEDNLFAPPK;RT(0.002)PS(0.998)DDEEDNLFAPPK;RT(0.24)PS(0.76)DDEEDNLFAPPK 204.51 3.1793000000000003e-17 118285800.0 1075664.0 1072497.0 1108043.0 1227586.0 1426633.0 1231390.0 1238469.0 1117211.0 1124985.0 1054833.0 True False 1257752.6698675868 1178967.4142742527 1134462.94739648 1158808.336307509 1147094.5048206828 1166813.7406617955 1121152.2505809097 1087885.3950329015 1141435.7773624756 1246065.872846566 1.00937895602126 0.9461517564725285 0.9104357739971359 0.9299735764853891 0.9205729246080797 0.9363981199455182 0.8997535965090688 0.8730560869528429 0.9160316498797381 1.0 20.248948907282433 -4.791327877389851 2.4026652528615977 0.9185099927319539 1.0296058604477272 0.4045688522937859 0.03101261673199299 0.49963273918118806 3.625980950843444 0.00785174991952525 0.11647548096128398 1.6168589039074304e-05 4.791327877389851 0.11109586771577329 RTPS(ph)DDEEDNLFAPPK ddPTM_PC-9_Lapatinib_30min_R1 7 RTPSDDEEDNLFAPPK 16 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 RT(0.239)PS(0.761)DDEEDNLFAPPK;RTPS(1)DDEEDNLFAPPK;RT(0.251)PS(0.749)DDEEDNLFAPPK;RT(0.477)PS(0.523)DDEEDNLFAPPK;RT(0.005)PS(0.995)DDEEDNLFAPPK;RT(0.249)PS(0.751)DDEEDNLFAPPK;RT(0.256)PS(0.744)DDEEDNLFAPPK 180.93 4.9059e-06 199411700.0 342545.0 372449.0 371190.0 344650.0 370275.0 356980.0 310391.0 323134.0 384287.0 295038.0 True False 337660.24548494077 371586.6172236984 340672.1910348362 369996.71071869606 348496.15248865914 341712.7975610245 326461.5272251727 338147.98529866297 341004.55133849126 346034.9251865767 0.9757981663350299 1.0738413673803147 0.9845023326797174 1.0692467256569538 1.007112655755067 0.9875095624430923 0.9434351953033344 0.9772076767000869 0.9854628146411143 1.0 18.400558130364274 -6.71097080367331 3.1816981278057646 0.9741315179390904 1.0272082919099919 0.32029442811718967 0.032152062280455335 0.25716198761973624 5.310588484976235 0.010761794073771945 0.010320386553067853 1.9454908667927301e-07 6.71097080367331 0.05307677397090149 RTPS(ph)EADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTPSEADR 8 1 G3V3Z8;P49757-3;P49757;P49757-9;P49757-8;P49757-7;P49757-6;P49757-5;P49757-4;P49757-2 G3V3Z8 NUMB Protein numb homolog 1 RT(0.38)PS(0.62)EADR 55.721000000000004 0.040494 56155000.0 6725.1 9996.1 10030.0 10493.0 14553.0 8671.0 10609.0 7996.7 8822.2 10390.0 True False 7863.526603220429 10988.446746076554 10269.153238986824 9905.11122876499 11701.444119584618 8216.277495576896 9604.038717491423 7786.795098204014 8951.207985037358 12273.62475280525 0.6406849452866927 0.895289449318144 0.8366846343937405 0.8070241210935739 0.9533812834639698 0.6694255088496974 0.7824940806746052 0.6344332057588994 0.7293043550961974 1.0 13.583273760630371 -6.784536533222972 24.99903841575969 0.7414937088491447 0.8298996331192319 0.05158124507444373 0.1188301385236452 517.3771003005209 559975.3657035603 0.03960654515674302 0.03495094489804213 1.6423414986931738e-07 6.784536533222972 0.0884059242700872 RTPS(ph)EAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTPSEAER 8 1 A0A0C4DGH3;Q9Y6R0 A0A0C4DGH3 NUMBL Numb-like protein 1 RT(0.02)PS(0.98)EAER 82.494 0.024076 3294300.0 24943.0 29052.0 32976.0 32186.0 40574.0 32665.0 30788.0 28406.0 28695.0 22186.0 True False 29165.35725329397 31936.090562020818 33762.2729021764 30382.722768419895 32623.81596289607 30951.989896553958 27871.537754182853 27660.37259864485 29114.610089393456 26208.146175720645 1.112835568671885 1.2185558775464465 1.2882358285018243 1.1592854589832302 1.244796779755408 1.181006458412844 1.063468494387565 1.0554112608036945 1.1108992560628104 1.0 14.677727688283223 -7.210969519461578 3.860833763888364 1.0607684155871082 1.2079164726139142 0.6587905560150606 0.0506744661520196 0.14364127308083624 4.470914340123933 0.020577164182339642 0.015100889960686325 6.152200498192013e-08 7.210969519461578 0.147148057026806 RTPS(ph)EAER ddPTM_PC-9_Lapatinib_30min_R1 2 RTPSEAER 8 1 A0A0C4DGH3;Q9Y6R0 A0A0C4DGH3 NUMBL Numb-like protein 1 RT(0.061)PS(0.939)EAER;RT(0.005)PS(0.995)EAER 89.40299999999999 0.01128 66937000.0 17626.1 20716.1 21050.2 17570.4 20540.4 17879.7 20872.8 19451.6 23714.0 18411.0 True False 17374.748581769127 20668.133143243384 19319.533812121837 18862.585829136166 19332.254055980164 17115.026910616405 21953.49145260524 20355.392347557008 21043.079600509453 21593.316818884567 0.8046354678857828 0.9571541656429522 0.8946996876008331 0.8735381408677233 0.8952887700454163 0.7926075949410585 1.0166799124350216 0.9426709438984879 0.9745181704603204 1.0 14.39829724359666 -7.278006712674342 24.998769406503826 0.9786898372853701 0.8761114617349071 0.5765550167670499 0.04752019227940092 669.1997981142622 1009764.4177257414 0.019476035128932912 0.013172745324664377 5.272217123554051e-08 7.278006712674342 -0.10257837555046301 RTPS(ph)PGPVESK ddPTM_PC-9_Lapatinib_30min_R1 1 RTPSPGPVESK 11 1 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 RT(0.034)PS(0.964)PGPVES(0.002)K 55.975 0.037842 8877500.0 87720.0 96399.0 98544.0 77314.0 92736.0 83004.0 75035.0 91032.0 98825.0 62996.0 True False 86469.09671412199 96175.79403823694 90442.09271084022 82999.92947194328 87281.45080599096 79454.11241177456 78919.94515092518 95261.67904865461 87694.28782661498 73884.77466310633 1.1703236168533584 1.301699768007297 1.2240964816260262 1.1233698668013739 1.1813184949669222 1.0753786930265787 1.0681489591161075 1.2893275980473773 1.186906074038611 1.0 16.17298948030681 -5.686202037652919 5.424875674051883 1.1412172703682286 1.2417025075108838 0.23993285378096485 0.0802331676888762 0.30649155090569236 15.784798684889228 0.022237543769351012 0.03880089954007582 2.0596715128652877e-06 5.686202037652919 0.10048523714265523 RTPS(ph)VGK ddPTM_PC-9_AZD4547_30min_R2 1 RTPSVGK 7 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 RT(0.034)PS(0.966)VGK 55.461000000000006 0.043623 12741000.0 51254.0 60079.0 48329.0 69709.0 57571.0 52035.0 35855.0 35008.0 42851.0 58126.0 True False 67551.70585057234 79498.3618411212 47688.12588239238 53638.667043313915 49578.26039779617 48781.243224152284 39046.02553966128 29598.318003810044 45116.01637794967 56091.026432177445 1.2043228685118215 1.4173098068948118 0.850191713643439 0.9562789354224279 0.8838893411541292 0.8696799885296483 0.6961189342269185 0.5276836579127127 0.8043357244050753 1.0 15.775482363265581 -5.394102557322667 0.8117678082482893 0.7482796951714681 1.4294281074057047 0.5899765578606841 0.15179828623450647 0.7983489030336415 0.7198069069720046 0.06387791202489225 0.41953944890620487 4.035500845880238e-06 5.394102557322667 0.6811484122342366 RTPS(ph)VGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTPSVGK 7 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 RT(0.134)PS(0.866)VGK 58.592 0.037823 2054500.0 12504.0 14793.0 13487.0 15920.0 32350.0 26588.0 28117.0 34679.0 30116.0 24151.0 True False 14620.680234742707 16261.551276468874 13808.581229732326 15028.054013336388 26011.2497264181 25193.67847450104 25453.55421054824 33768.71299543777 30556.38952612556 28529.385120789197 0.5124779301355746 0.5699930512914972 0.484012577602666 0.5267570243701303 0.9117353779722317 0.8830782145438724 0.8921872694690633 1.1836467155694395 1.071049705303999 1.0 14.800161033137588 -6.522242831023866 1.099171904167306 1.0591822575505192 0.49878489858235553 0.8777732617997032 0.0855292009916148 0.1645321588585592 0.42229912689428195 0.04307507036260965 0.0494786774058273 3.004395957659924e-07 6.522242831023866 -0.5603973589681637 RTQS(ph)LSALPK ddPTM_PC-9_AZD4547_30min_R2 3 RTQSLSALPK 10 1 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 RT(0.241)QS(0.754)LS(0.005)ALPK;RT(0.334)QS(0.665)LS(0.002)ALPK;RT(0.219)QS(0.777)LS(0.004)ALPK 96.756 0.0024793000000000003 58726000.0 363838.0 359039.0 446720.0 553015.0 560099.0 480275.0 427412.0 481033.0 472314.0 463961.0 True False 479530.9156994688 475091.33535968146 440796.2009183372 425525.93574657844 482338.9218624879 450243.3283266976 465450.8399932423 406700.40288867505 497279.5537918584 447717.86660873715 1.0710560186746652 1.061139996396137 0.9845401173224815 0.9504332247666311 1.0773278393287937 1.0056407436609347 1.0396074731589884 0.9083854659838548 1.110698479733518 1.0 18.772230365949447 -5.176999618645064 6.388863674809335 1.0076161567919792 1.0676598490645373 0.1441304080268061 0.05500414794932712 0.43125356714098395 26.749505996994632 0.013312062399818574 0.03616812003964019 6.652737403798131e-06 5.176999618645064 0.060043692272558014 RTQS(ph)LSALPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RTQSLSALPK 10 1 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 RT(0.022)QS(0.865)LS(0.113)ALPK;RT(0.06)QS(0.94)LSALPK 96.866 0.0024599 21049700.0 58020.0 55041.0 64862.0 97595.0 106102.0 107611.0 115880.0 101469.0 101398.0 85186.0 True False 67841.64005276488 60505.10672670343 66408.55607050472 92127.06855725896 85312.0747595801 101967.68972166129 104903.00750145224 98805.54626529255 102880.75392383066 100629.54746799485 0.6741721667221237 0.6012658135618371 0.6599309819178697 0.9155071335937379 0.8477835477369461 1.01329770715795 1.0424672488447448 0.9818740991229994 1.0223712270648122 1.0 16.61869445479485 -5.953592363117769 1.1385842596310434 1.0101154231656209 0.6107131548441765 0.8974597259702244 0.05161668116636073 0.14481263031808644 0.37987182186645696 0.019688672844075123 0.04159924244791583 1.1127757092421447e-06 5.953592363117769 -0.3994022683214443 RTQS(ph)LSALPK ddPTM_PC-9_Lapatinib_30min_R1 3 RTQSLSALPK 10 1 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 RT(0.086)QS(0.908)LS(0.006)ALPK;RT(0.028)QS(0.97)LS(0.002)ALPK;RT(0.333)QS(0.657)LS(0.009)ALPK 126.32 0.00016051 41429000.0 282220.0 274130.0 277775.0 232198.0 312197.0 339143.0 295264.0 305632.0 355405.0 244905.0 True False 278195.4910471909 273495.268827497 254937.41174250853 249274.61550982107 293834.1862629179 324638.644470946 310551.32518215233 319832.778484471 315375.54631943407 287236.5029346004 0.9685241541550588 0.9521605577051881 0.8875522753476569 0.8678375240022237 1.022969515576576 1.1302137477452214 1.0811694266200573 1.1134823576281052 1.0979647193074222 1.0 18.131879577554315 -6.480064401809717 4.578116983624702 1.090781219480136 0.9201902069208598 0.7732089093041379 0.04218093802562519 0.09475471772960004 4.472038957379506 0.01373341081748675 0.015107696161955031 3.310820214749654e-07 6.480064401809717 -0.17059101255927622 RTQS(ph)SLTVSEVLTR ddPTM_PC-9_AZD4547_30min_R2 2 RTQSSLTVSEVLTR 14 1 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 RTQS(0.822)S(0.157)LT(0.002)VS(0.019)EVLTR;RT(0.001)QS(0.835)S(0.159)LT(0.002)VS(0.001)EVLTR 94.61 0.0015600999999999998 8099200.0 14898.2 14310.5 25163.0 36333.0 32984.0 26519.0 17972.2 25819.0 19679.5 25203.0 True False 19635.51769818936 18936.08926792 24829.32217878786 27956.98818925426 28404.740945283404 24860.76273779753 19571.69098323527 21829.266811596528 20719.718193504486 24320.650641196175 0.8073598847281339 0.7786012614253258 1.0209152109084638 1.1495164583261017 1.1679268521364838 1.0222079624665334 0.8047355011992666 0.8975609712768313 0.8519393045516572 1.0 14.569894204723669 -10.62961913435689 13.06236149742084 1.000000754583092 0.9512868952586883 0.012870558538039978 0.13448969216451237 0.0 0.0 0.14821448171525622 0.03594729196224582 2.3462855484003554e-11 10.62961913435689 -0.04871385932440375 RTQS(ph)SLTVSEVLTR ddPTM_PC-9_Lapatinib_30min_R1 1 RTQSSLTVSEVLTR 14 1 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 RT(0.001)QS(0.958)S(0.033)LT(0.003)VS(0.005)EVLTR 84.94 0.00325 3692400.0 10047.0 9775.8 6593.9 7289.7 7876.4 6336.6 5926.7 6365.1 8847.0 7259.6 True False 9903.727937605856 9753.164735723356 6051.774995190076 7825.808855726332 7413.125637598203 6065.598389336058 6233.555526434185 6660.845782939965 7850.557696959897 8514.41218719104 1.163172244879674 1.1454889100149366 0.7107683844921532 0.9191249711282908 0.8706561856084915 0.7123919133796527 0.7321181297532033 0.7823024815454022 0.92203167104949 1.0 13.055691218101215 -5.2482339249265415 24.326437171356314 0.8201705349278924 1.1543306896886134 0.6537479000871389 0.09379965150880308 308.0437762132687 567459.2001442475 0.023642492483569883 0.06168183821995864 5.64632763588466e-06 5.2482339249265415 0.33416015476072103 RTS(ph)DPALCTLIVSAAADSAVR ddPTM_PC-9_AZD4547_30min_R2 1 RTSDPALCTLIVSAAADSAVR 21 1 Q6IA86-4;Q6IA86-7;Q6IA86-2;Q6IA86-3;Q6IA86-5;Q6IA86;Q6IA86-6 Q6IA86-4 ELP2 Elongator complex protein 2 1 RT(0.421)S(0.578)DPALCTLIVSAAADSAVR 69.255 0.001831 2731100.0 13287.0 12286.0 17886.0 26536.0 22064.0 13916.0 14621.0 16396.0 18109.0 19146.0 True False 17511.989613231253 16257.209234175269 17648.81995349521 20418.53517711312 19000.79445236275 13045.830320117288 15922.2406753699 13862.374942597959 19066.204769743763 18475.704367588845 0.9478388084598173 0.8799236505805218 0.9552447691496838 1.1051559805715718 1.0284205719212007 0.7061073321244001 0.8617934319896144 0.7503029203539402 1.0319609142042134 1.0 14.173341746262233 -6.72396226119973 24.999957536104347 0.8539114419142224 0.9827820194007213 0.2107116605227327 0.10737967177116604 240.9086402181614 160702.92156219 0.03562981107845302 0.0356289788176774 1.8881554166293062e-07 6.72396226119973 0.12887057748649888 RTS(ph)DPALCTLIVSAAADSAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSDPALCTLIVSAAADSAVR 21 1 Q6IA86-4;Q6IA86-7;Q6IA86-2;Q6IA86-3;Q6IA86-5;Q6IA86;Q6IA86-6 Q6IA86-4 ELP2 Elongator complex protein 2 1 RT(0.251)S(0.748)DPALCTLIVSAAADSAVR 62.847 0.0029927 2484300.0 5127.9 8457.3 6733.0 8433.2 9717.0 8188.1 8076.9 7739.6 7988.7 5248.5 True False 5995.952189358379 9296.884851651472 6893.540255044696 7960.715144803288 7813.023604068143 7758.701621673755 7311.797560307892 7536.443700784046 8105.519624364431 6200.011502896861 0.9670872685569795 1.4994947746964087 1.1118592686197104 1.283983931494928 1.260162759442886 1.251401165634712 1.1793199991470282 1.2155531803872874 1.3073394493828359 1.0 12.598055176799804 -10.717118143354982 5.087202082497518 0.9999811987363999 1.2361876609269022 0.21982845799724726 0.1300062443760613 2.4943877962510237e-05 3.950874765327684e-06 0.11326056968195242 0.027467537775372315 1.9181468663610868e-11 10.717118143354982 0.23620646219050234 RTS(ph)EEDTPK ddPTM_PC-9_AZD4547_30min_R2 1 RTSEEDTPK 9 1 A0A1B0GW41;Q8WYH8-2;Q8WYH8 A0A1B0GW41 ING5 Inhibitor of growth protein 5 1 RT(0.08)S(0.92)EEDTPK 123.26 9.030299999999999e-05 0.0 31777.0 29471.0 23962.0 30384.0 27957.0 30139.0 27943.0 23786.0 40360.0 36395.0 True False 41881.42499733947 38996.92441318407 23644.248223507322 23379.438228120496 24075.653122947122 28254.40356553716 30429.87286723625 20110.420247904072 42493.34720342695 35120.822127775835 1.1924955755582074 1.1103647936060916 0.6732259323966084 0.6656859609681663 0.6855093834465374 0.8044915196672385 0.8664339563728585 0.5726067623001183 1.2099189207140013 1.0 15.100038996227472 -5.1632706232945464 5.3349994026564405 0.7872840881608817 1.16879959869271 0.36809099432869163 0.1778967137465374 0.20695465815108305 8.85723080306277 0.04340658896591412 0.12129457759658924 6.866404382483282e-06 5.1632706232945464 0.3815155105318283 RTS(ph)EEDTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSEEDTPK 9 1 A0A1B0GW41;Q8WYH8-2;Q8WYH8 A0A1B0GW41 ING5 Inhibitor of growth protein 5 1 RT(0.159)S(0.639)EEDT(0.202)PK 89.189 0.014012 4309300.0 18115.0 25972.0 19288.0 16065.0 31105.0 25900.0 15157.0 23451.0 26164.0 27980.0 True False 21181.511712441163 28550.32851703167 19747.89907014735 15164.93013343273 25010.198539110803 24541.758405655804 13721.219232822843 22835.43609838837 26546.59900257502 33052.55251044187 0.6408434478925511 0.8637858909084898 0.5974697132364784 0.4588126780417902 0.7566797914082324 0.7425072056962209 0.4151334221007008 0.6908826811839801 0.8031633561186687 1.0 15.012474068890914 -8.523123471476866 2.3611389215341343 0.9970541673989525 0.6439722836499341 0.4356430535080156 0.1270032541142781 0.2886784831184819 3.7691684479929517 0.12565411773571986 0.03437215274981485 2.998309967537833e-09 8.523123471476866 -0.3530818837490184 RTS(ph)EEDTPK ddPTM_PC-9_Lapatinib_30min_R1 1 RTSEEDTPK 9 1 A0A1B0GW41;Q8WYH8-2;Q8WYH8 A0A1B0GW41 ING5 Inhibitor of growth protein 5 1 RT(0.07)S(0.911)EEDT(0.02)PK 98.368 0.0020559000000000003 6936900.0 24771.0 27516.0 23492.0 27295.0 38277.0 27432.0 37667.0 36861.0 30560.0 27144.0 True False 24417.76099755493 27452.288392577993 21560.578441742407 29302.365353450772 36025.62211547744 26258.79730711528 39617.2129539535 38573.69662769638 27118.010988933485 31835.804232893486 0.7669905499772466 0.862308619306487 0.6772430903273843 0.9204217094404322 1.1316071003557353 0.8248196626358221 1.2444231866779758 1.2116451133293862 0.8518085734713287 1.0 14.958362589448969 -5.996862112565988 5.294331473265502 1.05230244182645 0.7791420262361886 0.45554687645125547 0.13452372057432121 0.15477124147889232 13.86019500590724 0.03903200727880166 0.05569373529413856 1.0072514179468413e-06 5.996862112565988 -0.2731604155902614 RTS(ph)ETS(ph)ISPPGSSIGSPNR ddPTM_PC-9_AZD4547_30min_R2 1 RTSETSISPPGSSIGSPNR 19 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 2 RT(0.226)S(0.756)ET(0.178)S(0.661)IS(0.156)PPGS(0.012)S(0.01)IGSPNR 80.362 0.014427 5480000.0 14216.0 14663.0 19724.0 25893.0 23484.0 13312.0 12986.0 22397.0 17046.0 18470.0 True False 18736.392288830848 19402.527999406804 19462.446872567343 19923.768892862157 20223.651963346925 12479.598535599407 14141.728842784587 18936.05828185939 17947.016759901282 17823.370921830465 1.0512260767620616 1.0886003598590968 1.0919621747157437 1.117845158485653 1.1346704308653837 0.7001817215347359 0.7934373864970448 1.062428558823633 1.0069372869258628 1.0 14.121482598131566 -6.70820842871567 24.999944380823045 0.9090489968992139 1.0972958605378993 0.45300488743937084 0.10120129641888927 96.04236795596614 45105.88705049245 0.036176034073815255 0.036176003710446505 1.957904800814899e-07 6.70820842871567 0.18824686363868537 RTS(ph)ETS(ph)ISPPGSSIGSPNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSETSISPPGSSIGSPNR 19 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 2 RT(0.166)S(0.834)ET(0.003)S(0.854)IS(0.107)PPGS(0.03)S(0.006)IGSPNR 163.11 3.3056999999999997e-20 0.0 13262.0 12196.0 13582.0 12127.0 12630.0 10185.0 9011.0 13709.0 9331.8 9164.5 True False 15506.994663560297 13406.738279443949 13905.846390021836 11447.563506264469 10155.242165213616 9650.880670332217 8157.412846009542 13349.153275886161 9468.259920968874 10825.951303857919 1.4323909491477436 1.2383889325888935 1.284491865861836 1.0574187140658053 0.9380461707411071 0.8914579790224111 0.753505407243295 1.233069769224722 0.8745891843790928 1.0 13.402206183351932 -5.814913501061717 2.0124037005622304 0.946346290679525 1.334500109841248 0.6482655199847513 0.12226220399362807 0.20742497265290877 1.7156793290763763 0.03798837155789811 0.07102082152812399 1.5313924405272792e-06 5.814913501061717 0.38815381916172287 RTS(ph)ETS(ph)ISPPGSSIGSPNR ddPTM_PC-9_Lapatinib_30min_R1 1 RTSETSISPPGSSIGSPNR 19 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 2 RT(0.235)S(0.685)ET(0.175)S(0.886)IS(0.018)PPGSSIGSPNR 66.31 0.007516199999999999 8275700.0 14932.0 12646.0 18575.0 15396.0 13042.0 12869.0 10478.0 12824.0 10732.0 11438.0 True False 14719.066941806575 12616.71896396792 17047.835201573518 16528.273199550415 12274.895201558556 12318.622869104214 11020.499570752256 13419.849856313664 9523.249147029914 13415.043059823009 1.097206089922217 0.9404903814102539 1.2707998867801202 1.2320700817615178 0.9150097503839474 0.9182693498761486 0.8215031082350961 1.000358313906949 0.7098932969921872 1.0 13.71156406494128 -6.353098629797095 6.36488198386878 0.8897101182478973 1.1303337908006308 0.5180384720246605 0.11390837355161494 0.2042172851895367 11.80685261955843 0.03591551099484966 0.040789147835641366 4.435079102944507e-07 6.353098629797095 0.24062367255273354 RTS(ph)ETSIS(ph)PPGSSIGSPNR ddPTM_PC-9_Lapatinib_30min_R1 1 RTSETSISPPGSSIGSPNR 19 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 2 RT(0.012)S(0.76)ET(0.332)S(0.422)IS(0.458)PPGS(0.013)S(0.003)IGSPNR 166.01 5.0964e-07 6273300.0 16371.0 18594.0 18977.0 15600.0 17736.0 18177.0 14116.0 14655.0 20953.0 17939.0 True False 16137.546537926295 18550.946735411955 17416.784313338394 16747.27604007445 16692.80335031762 17399.612082656546 14846.85740988153 15335.924800707806 18593.052495128373 21039.732247785032 0.7670034175280526 0.881710209851407 0.8278044657708016 0.7959833253979516 0.7933942862830378 0.8269882847244074 0.7056580965494245 0.7289030402144163 0.8837114596401656 1.0 14.360828724519463 -8.543394226376611 5.366753264511564 0.9999357855202202 0.794159807884959 0.6545685026651068 0.04768644718617378 0.10695724374432314 14.399148475513215 0.04972728129753692 0.012914207359258653 2.861579221304069e-09 8.543394226376611 -0.20577597763526123 RTS(ph)ETSISPPGSSIGSPNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSETSISPPGSSIGSPNR 19 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 RT(0.04)S(0.919)ET(0.04)SISPPGSSIGSPNR 183.21 1.3999e-10 5926500.0 13185.0 13406.0 11517.0 13277.0 14641.0 10441.0 9281.3 11296.0 8973.1 6937.5 True False 15416.960084379612 14736.859082832545 11791.608958465724 12533.132734614774 11772.201151297906 9893.455579669979 8402.108073207006 10999.491969101327 9104.314612062602 8195.213832780213 1.8812151090814715 1.7982275244468013 1.4388409136196314 1.529323455171264 1.4364727256060146 1.2072236041110889 1.0252457403367843 1.3421848646711598 1.1109306966031878 1.0 13.00056587785099 -1.5228789492338375 0.2326443180949659 0.9995645109978241 6.430377229070938 0.8705082569217474 0.10360408930375428 17.095862300856012 0.22505016357070495 0.15340237973193022 35.48448525551556 0.02999998591139465 1.5228789492338375 5.430812718073114 RTS(ph)ETSISPPGSSIGSPNR ddPTM_PC-9_Lapatinib_30min_R1 1 RTSETSISPPGSSIGSPNR 19 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 RT(0.236)S(0.669)ET(0.092)S(0.003)IS(0.001)PPGSSIGSPNR 69.612 0.0034899 12030000.0 18060.0 13362.0 18823.0 11626.0 15929.0 12449.0 10831.0 12243.0 17422.0 13997.0 True False 17802.461088201628 13331.061109958828 17275.445598881197 12481.014823199079 14992.087537618927 11916.58529003639 11391.776183509983 12811.854475268892 15459.750898206777 16416.362800169845 1.0844339458687793 0.8120593624929453 1.0523308852983235 0.7602789348119151 0.9132405101003139 0.7258968040053976 0.6939281448745834 0.7804319769989696 0.9417281456551891 1.0 14.002846899392518 -4.757003534211026 24.93562297020986 0.8426809788377813 1.0844343179846427 0.26447019235652414 0.1143940675483013 176.07605182381963 989663.6978847762 0.028667760206141642 0.2209489992344956 1.7498324487423775e-05 4.757003534211026 0.24175333914686148 RTS(ph)FLEGTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSFLEGTLR 10 1 E9PEW5;A0A0A0MQX1;Q9HD67-3;Q9HD67 E9PEW5 MYO10 Unconventional myosin-X 1 RT(0.194)S(0.796)FLEGT(0.009)LR 72.321 0.01415 3801100.0 13289.0 11469.0 8577.6 11116.0 16403.0 9136.9 7301.6 10241.0 8104.5 7930.7 True False 15538.565230285982 12607.566524019574 8782.122514729153 10493.206558558251 13188.94989992073 8657.744879406817 6609.939588993811 9972.184601236426 8223.01298029236 9368.47313061334 1.6586016753904802 1.3457440020638856 0.9374123608287706 1.12005514796959 1.4078014331730564 0.9241361701850777 0.7055514273072445 1.0644407538140168 0.8777324613785824 1.0 13.193598221939432 -1.5228787453030108 0.5388814397561413 0.9569466735316211 29.737020797386194 0.5946010094820227 0.17332276792630044 97.00180430134314 0.9198785147645221 0.09458261109294822 3216.903825368426 0.029999999998433786 1.5228787453030108 28.780074123854572 RTS(ph)FLEGTLR ddPTM_PC-9_Lapatinib_30min_R1 1 RTSFLEGTLR 10 1 E9PEW5;A0A0A0MQX1;Q9HD67-3;Q9HD67 E9PEW5 MYO10 Unconventional myosin-X 1 RT(0.356)S(0.644)FLEGTLR 85.271 0.0055063 7668800.0 16094.0 13317.0 13799.0 14600.0 8838.2 10899.0 8573.6 8123.2 16372.0 12773.0 True False 15864.49660872186 13286.165304694045 12664.49948568037 15673.732704172238 8318.354452569763 10432.875176809916 9017.499057053019 8500.633527199567 14528.012955196962 14980.796031047339 1.0589888932365858 0.8868797944487588 0.8453822787142619 1.0462549968432122 0.5552678532789695 0.6964166093168903 0.6019372427449429 0.5674353692275236 0.9697757665939784 1.0 13.870826665531155 -6.2547449916502496 24.988310511692227 0.7019143863966147 0.9460557119221586 0.32400844306872334 0.15705126024408053 585.2006492157748 2184392.2730148463 0.045210884910139304 0.05703631425304663 5.562307681071634e-07 6.2547449916502496 0.2441413255255439 RTS(ph)FSFQK ddPTM_PC-9_AZD4547_30min_R2 1 RTSFSFQK 8 1 H0Y7F8;Q9BPZ7-4;Q9BPZ7-3;Q9BPZ7-2;Q9BPZ7 H0Y7F8 MAPKAP1 Target of rapamycin complex 2 subunit MAPKAP1 1 RT(0.441)S(0.559)FSFQK 100.82 0.0021893 67906000.0 53742.0 53045.0 73214.0 102880.0 86974.0 66575.0 62671.0 90819.0 64552.0 68635.0 True False 70830.83809695742 70190.75889848825 72243.1345228223 79162.60548015528 74899.1613805202 62412.054725625705 68248.5975901858 76785.0103630034 67964.08693448013 66232.1095408681 1.0694335208098982 1.0597693382418611 1.0907569609910301 1.1952300180218252 1.1308587617053654 0.9423232199348074 1.0304457771811337 1.1593320957959778 1.0261501166974507 1.0 16.01524318939888 RTS(ph)FSFQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSFSFQK 8 1 H0Y7F8;Q9BPZ7-4;Q9BPZ7-3;Q9BPZ7-2;Q9BPZ7 H0Y7F8 MAPKAP1 Target of rapamycin complex 2 subunit MAPKAP1 1 RT(0.237)S(0.755)FS(0.008)FQK 58.63 0.035256 4216000.0 19863.0 17426.0 20819.0 22937.0 25938.0 20145.0 19416.0 23590.0 17976.0 18302.0 True False 23225.413587867442 19155.93811557809 21315.40391649717 21651.914252757324 20855.635097490962 19088.560736754298 17576.775920333057 22970.787495671044 18238.86499274915 21620.007721447706 1.0742555639712896 0.8860282735502826 0.9859110223791289 1.0014757872300835 0.9646451271523616 0.8829118371598852 0.8129865699768627 1.0624782281129033 0.8436104754327003 1.0 14.400079417871426 -6.594053682644854 7.034778153611764 0.9178162140972728 0.9800650040781531 0.13349384250649565 0.07975535735349504 0.4847765507012688 39.452111945490664 0.02553986179298596 0.02554383279972095 2.5465154612624234e-07 6.594053682644854 0.06224878998088035 RTS(ph)FSTSDVSK ddPTM_PC-9_AZD4547_30min_R2 1 RTSFSTSDVSK 11 1 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 RT(0.203)S(0.773)FS(0.004)T(0.004)S(0.015)DVS(0.001)K 76.357 0.030414 9023300.0 31215.0 24826.0 25838.0 41921.0 42023.0 28334.0 25956.0 34506.0 26475.0 32702.0 True False 41140.72068766564 32850.519001109795 25495.371237750718 32256.761122993663 36188.83181978059 26562.27050087692 28266.03371656528 29173.890568997635 27874.414450216285 31557.112933714117 1.303690891308148 1.0409861976319723 0.8079120321083834 1.022170855450217 1.1467725801088149 0.8417205514544727 0.8957103831373369 0.9244790748215005 0.8833005258993952 1.0 14.945677603065066 -6.771054922058528 24.99926572199601 0.9034888160456893 1.0464259372937479 0.28361899658561507 0.12157299391816889 312.7885715396447 813207.9471955623 0.04472090292138588 0.039939774474067206 1.6941235434399815e-07 6.771054922058528 0.14293712124805857 RTS(ph)FSTSDVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSFSTSDVSK 11 1 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 RT(0.15)S(0.845)FS(0.002)T(0.002)SDVSK 77.91199999999999 0.027875 9119700.0 26879.0 22221.0 20070.0 27696.0 27602.0 20623.0 23185.0 23855.0 19245.0 16913.0 True False 31429.08381555097 24426.954026527063 20548.544915898845 26144.28291164349 22193.58624261491 19541.493575283384 20988.74895513608 23228.83152646177 19526.42171703701 19979.193016765654 1.57309075442522 1.222619652657094 1.0284972420385257 1.3085755210285204 1.110834968358884 0.9780922362021843 1.050530366142579 1.1626511394613968 0.9773378584736282 1.0 14.286210691697685 -1.6437377665772985 0.9041851797719126 1.072691717272556 199.99960033202834 0.7123532751599619 0.09547085946555407 399.7977971246985 1.1095377090646237 0.03247302501398526 163793.730590376 0.0227123584367818 1.6437377665772985 198.92690861475577 RTS(ph)FSTSDVSK ddPTM_PC-9_Lapatinib_30min_R1 4 RTSFSTSDVSK 11 1 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 RT(0.023)S(0.44)FS(0.44)T(0.074)S(0.023)DVSK;RT(0.22)S(0.755)FS(0.02)T(0.004)S(0.001)DVSK;RT(0.037)S(0.901)FS(0.01)T(0.01)S(0.017)DVS(0.025)K;RT(0.016)S(0.972)FS(0.005)T(0.005)S(0.002)DVSK 98.25299999999999 0.0027779 156654800.0 454745.0 382801.0 398785.0 297876.0 322337.0 292155.0 274208.0 274473.0 335262.0 262635.0 True False 448260.2529099801 381914.6478037241 365998.43665461696 319782.7947252062 303377.77139892476 279660.21169656835 288405.14852995175 287226.0175929493 297501.26309462776 308031.1098108606 1.455243443382144 1.2398573898533496 1.188186598682678 1.0381509676784317 0.9848932842699132 0.9078959974798885 0.9362857820011761 0.9324578214496382 0.9658156388077216 1.0 18.232716538679497 -5.032640679533445 0.7659829189848779 0.9378527852777164 1.625963949516709 0.953241232807441 0.03605772081769787 0.3765637096259982 0.21459740318104276 0.014800933565015049 0.2087263512636549 9.275969681275222e-06 5.032640679533445 0.6881111642389927 RTS(ph)FYLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSFYLPK 8 1 Q9NS23-3;Q9NS23-4;Q9NS23-2;Q9NS23-5;Q9NS23 Q9NS23-3 RASSF1 Ras association domain-containing protein 1 1 RT(0.119)S(0.881)FYLPK 88.681 0.004947999999999999 8628400.0 17047.0 19841.0 22067.0 23178.0 22151.0 17258.0 17792.0 15291.0 13346.0 11664.0 True False 19932.720406402685 21810.68335539911 22593.16096956353 21879.41180408987 17810.670562283984 16352.96009902734 16106.612957074869 14889.627452153705 13541.160001848577 13778.590867826797 1.4466443337791433 1.58294005276892 1.6397294314267563 1.5879281135474166 1.2926336759060137 1.1868383534931521 1.1689593741174242 1.0806349934463324 0.9827681314979295 1.0 13.750140731165734 -6.643160275329702 1.307964228471256 1.0542656546552598 1.5802398413797458 0.9134448244867681 0.07015182248283912 0.1234390709982488 0.4423789397801524 0.03419187009389655 0.03434842886797298 2.2742579664703898e-07 6.643160275329702 0.525974186724486 RTS(ph)FYLPK ddPTM_PC-9_Lapatinib_30min_R1 2 RTSFYLPK 8 1 Q9NS23-3;Q9NS23-4;Q9NS23-2;Q9NS23-5;Q9NS23 Q9NS23-3 RASSF1 Ras association domain-containing protein 1 1 RT(0.111)S(0.888)FYLPK;RT(0.306)S(0.694)FYLPK 85.963 0.005882500000000001 14239700.0 50587.0 42478.0 53834.0 43817.0 45931.0 39766.0 46001.0 43575.0 52168.0 42878.0 True False 49865.62010348039 42379.64480084054 49407.976325249474 47039.44834922709 43229.428883820416 38065.300879073584 48382.70669537833 45599.65357835843 46292.2904866061 50289.40516865635 0.9915730746117457 0.842715173478614 0.9824728719607876 0.9353749202534842 0.8596130484908545 0.7569248582561954 0.962085483674275 0.9067447392831587 0.9205177577932159 1.0 15.61796686863318 -8.922024650708575 1.210370173930881 0.9998423573115385 0.900429165781235 0.15046568520534076 0.06750855818061584 2.8866888992074613 6.437959867188446 0.0660650252168313 0.02007081821042077 1.1966726058186794e-09 8.922024650708575 -0.09941319153030348 RTS(ph)LGEVSK ddPTM_PC-9_AZD4547_30min_R2 1 RTSLGEVSK 9 1 Q9ULJ8-3;Q9ULJ8;Q9ULJ8-4;Q9ULJ8-5 Q9ULJ8-3 PPP1R9A Neurabin-1 1 RT(0.152)S(0.848)LGEVSK 56.122 0.040368 4149700.0 25311.0 25262.0 30064.0 34336.0 24029.0 32002.0 28752.0 34775.0 24966.0 26580.0 True False 33359.3714984945 33427.447474665125 29665.331716531346 26420.36568591184 20692.9881207317 30000.909881028536 31310.872299995575 29401.32280000269 26285.651790900825 25649.442290322357 1.3005885711238694 1.3032426629906664 1.1565682941856479 1.030056146518256 0.8067617177212174 1.1696515480318264 1.2207233180976143 1.1462753251011595 1.0248040286169697 1.0 14.646639836425303 -5.422705988189717 3.0913122123842607 1.0649256825810975 1.3035505916063719 0.4476315658092852 0.1077860990537755 0.2657349276124072 4.795424543547215 0.03268378582416149 0.07716621179255216 3.7782788901250028e-06 5.422705988189717 0.23862490902527433 RTS(ph)LGEVSK ddPTM_PC-9_Lapatinib_30min_R1 1 RTSLGEVSK 9 1 Q9ULJ8-3;Q9ULJ8;Q9ULJ8-4;Q9ULJ8-5 Q9ULJ8-3 PPP1R9A Neurabin-1 1 RT(0.162)S(0.838)LGEVSK 78.324 0.026119999999999997 0.0 19053.0 27632.0 29916.0 22798.0 31747.0 28803.0 32484.0 33395.0 31512.0 29796.0 True False 18781.300726107733 27568.01980170502 27456.421959099516 24474.640971898563 29879.703877003463 27571.162833072376 34165.86257456729 34946.65361444128 27962.78672392904 34946.19889932562 0.5374347230213404 0.7888703398365029 0.7856769212067114 0.7003520194687288 0.8550201400467642 0.7889602789848609 0.9776703518741381 1.0000130118619475 0.800166759322962 1.0 15.09284792163599 -3.520716098350001 0.23921893559714646 0.9930021457247111 2.695901805653321e-17 0.643462194358242 0.08196641284886615 13.07642236759888 0.39464166983791593 0.12090591184203998 4.239512091052731 0.0003014976293365773 3.520716098350001 -0.9930021457247111 RTS(ph)MGGTQQQFVEGVR ddPTM_PC-9_AZD4547_30min_R2 3 RTSMGGTQQQFVEGVR 16 1 A0A2R8Y6G0;A0A2R8Y804;A0A2R8Y543;A0A2R8Y5C3;A0A2R8Y750;A0A2R8Y5Z1;B4DGU4;A0A2R8YCH5;A0A2R8Y5A3;P35222 A0A2R8Y6G0 CTNNB1 Catenin beta-1 1 RT(0.103)S(0.897)MGGTQQQFVEGVR;RT(0.009)S(0.972)MGGT(0.019)QQQFVEGVR;RT(0.415)S(0.574)MGGT(0.011)QQQFVEGVR 116.27 7.4336e-05 75394000.0 42456.9 82680.4 75445.90000000001 104829.6 86382.3 71723.40000000001 92633.1 129025.0 92405.8 84012.0 True False 55957.31104161948 109405.22239665514 74445.43807052476 80662.75532117493 74389.60871203463 67238.52445975124 100877.26644590696 109087.15094954282 97290.18193782045 81070.76545126246 0.6902279845286461 1.3495027682010303 0.9182772317017204 0.9949672347631551 0.9175885819994588 0.8293806538705153 1.2443112617032293 1.3455793878635949 1.2000649234810625 1.0 16.30689414427419 -7.2793178427050185 24.33528504295383 1.2262872193079501 0.9672804179450403 0.311286270452939 0.17718761128108165 690.1117095258434 939341.4590214605 0.0716366177420211 0.04842241995689897 5.256324362981731e-08 7.2793178427050185 -0.2590068013629099 RTS(ph)MGGTQQQFVEGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSMGGTQQQFVEGVR 16 1 A0A2R8Y6G0;A0A2R8Y804;A0A2R8Y543;A0A2R8Y5C3;A0A2R8Y750;A0A2R8Y5Z1;B4DGU4;A0A2R8YCH5;A0A2R8Y5A3;P35222 A0A2R8Y6G0 CTNNB1 Catenin beta-1 1 RT(0.238)S(0.676)MGGT(0.086)QQQFVEGVR 51.235 0.033155000000000004 91739000.0 25728.0 20801.0 35536.0 29734.0 52656.0 32665.0 26168.0 34934.0 38176.0 24829.0 True False 30083.24224883721 22865.985810980117 36383.31301103049 28068.100378928662 42338.43479425877 30951.989896553958 23689.177600086296 34017.019515632564 38734.25177810364 29330.301153744163 1.0256711000390437 0.7796028309126706 1.240468443208807 0.9569659797149961 1.443504946380479 1.05529055887661 0.8076690885617535 1.1597910071676887 1.320622368487308 1.0 14.840104263831591 -5.26194047003395 24.997305507976716 1.120577097451575 0.9026369691695115 0.18869458828658014 0.1827479650809002 72.14336369589563 3599162.389510153 0.0477189256403847 0.11002590553859144 5.470909490496051e-06 5.26194047003395 -0.21794012828206344 RTS(ph)MGGTQQQFVEGVR ddPTM_PC-9_Lapatinib_30min_R1 2 RTSMGGTQQQFVEGVR 16 1 A0A2R8Y6G0;A0A2R8Y804;A0A2R8Y543;A0A2R8Y5C3;A0A2R8Y750;A0A2R8Y5Z1;B4DGU4;A0A2R8YCH5;A0A2R8Y5A3;P35222 A0A2R8Y6G0 CTNNB1 Catenin beta-1 1 RT(0.002)S(0.998)MGGTQQQFVEGVR;RT(0.246)S(0.754)MGGTQQQFVEGVR 216.71 6.5453e-22 84555400.0 127478.0 121313.0 80889.0 64869.0 70197.0 56065.0 45964.0 48318.0 100085.0 47849.0 True False 125660.14034339788 121032.10720194863 74238.61866056951 69639.68265664032 66068.15047261202 53667.230643898336 48343.79101642074 50563.03067353118 88812.37335822675 56119.63589521518 2.239147463073826 2.15668019350546 1.3228635125000727 1.240914727006949 1.17727332721781 0.9563004069396335 0.8614416370535039 0.9009864349073983 1.582554340232257 1.0 15.776218028317107 -5.3077976994749685 1.8581369704968655 1.0753272552797135 2.3207448815442997 0.8242505128259154 0.199089335961843 0.1547233807924092 0.9581139568332863 0.05846413923145822 0.22771092185731528 4.922687880613256e-06 5.3077976994749685 1.2454176262645862 RTS(ph)PSSLPGR ddPTM_PC-9_AZD4547_30min_R2 1 RTSPSSLPGR 10 1 Q5SNT2;H0Y4R5 Q5SNT2 TMEM201 Transmembrane protein 201 1 RT(0.016)S(0.982)PS(0.002)SLPGR 105.66 0.0011133 15742000.0 5947.5 5494.0 11054.0 10293.0 12243.0 7224.7 10220.0 10240.0 6613.5 8579.2 True False 7838.681284314962 7269.828058974352 10907.416737444708 7920.1078752647545 10543.270779562956 6772.938366897916 11129.560201236598 8657.643291790864 6963.0761082721565 8278.844819305248 0.946832735170506 0.8781210685362777 1.317504673116949 0.9566682367081016 1.273519556131472 0.8181018626057898 1.3443373374125618 1.045754991276356 0.8410685621302043 1.0 13.015213761356964 -10.635819798523794 14.492316379152092 0.999999999854254 1.055874552795652 0.003506128547484111 0.18845122156822566 0.0 0.0 0.1732716503593578 0.0420245480209838 2.313024332502588e-11 10.635819798523794 0.05587455294139787 RTS(ph)QEGPGDSVK ddPTM_PC-9_AZD4547_30min_R2 1 RTSQEGPGDSVK 12 1 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 RT(0.102)S(0.884)QEGPGDS(0.014)VK 75.669 0.028636 3833700.0 7267.0 6986.6 9109.0 8537.2 9938.3 8375.6 7362.3 8858.9 10324.0 9346.7 True False 9577.754837009968 9244.881819590502 8988.208708285136 6569.080438425166 8558.538592545165 7851.872407960212 8017.530437335053 7489.960562270127 10869.705563136267 9019.474877914072 1.0618971688100105 1.0249911380349186 0.9965334822645276 0.7283218288584438 0.9488954410752228 0.8705465134325103 0.8889132178822878 0.8304209129303907 1.2051372957147253 1.0 13.138827725561521 -10.81430945243931 12.445502930060453 0.9999999988115971 0.9398703979847414 0.007152561175415961 0.1264631087670855 2.525120539416227e-10 7.313869518232014e-11 0.12217139602644453 0.029630915896835083 1.5335238954146923e-11 10.81430945243931 -0.0601296008268557 RTS(ph)QEGPGDSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSQEGPGDSVK 12 1 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 RT(0.135)S(0.83)QEGPGDS(0.034)VK 86.49799999999999 0.013353 2776300.0 10356.0 15189.0 12649.0 11010.0 14464.0 8443.9 9854.6 10729.0 9918.7 10244.0 True False 12109.06625967655 16696.86353939604 12950.600131599627 10393.145394901607 11629.883030692774 8001.087019363592 8921.100946874449 10447.375118315163 10063.742223163159 12101.156108540616 1.0006536690432704 1.379774245504685 1.0701952784874413 0.8588555755897117 0.9610555327424268 0.6611836875417776 0.737210632344311 0.8633369427357221 0.8316347738097921 1.0 13.562857264436266 -5.674812691642588 3.0436401106025706 0.8281439837497859 1.1983814929103 0.5606485831657635 0.12594070461488222 0.1637888784004279 3.030842631763796 0.03508168968003126 0.06551251129396422 2.114400770374788e-06 5.674812691642588 0.3702375091605141 RTS(ph)SEDNLYLAVLR ddPTM_PC-9_AZD4547_30min_R2 1 RTSSEDNLYLAVLR 14 1 Q15149-4 Q15149-4 PLEC Plectin 1 RT(0.001)S(0.682)S(0.318)EDNLYLAVLR 135.57 6.1348e-05 19052000.0 15340.0 9479.3 19085.0 35263.0 33804.0 24804.0 18937.0 24935.0 19376.0 25121.0 True False 20217.80090817847 12543.298347185217 18831.920430082526 27133.660157919054 29110.89809951368 23253.001958909823 20622.356314170007 21081.868699297396 20400.175803112015 24241.52143623731 0.834015346823735 0.5174303263175113 0.7768456480595203 1.1193051652838275 1.2008692678833848 0.9592220529586973 0.8507038788144207 0.8696594706214799 0.8415385914110539 1.0 14.565192627025054 -5.562765662569081 6.926205234773216 0.9741548298560319 0.6683302522058209 0.4843248496615986 0.129394667611894 0.16079601379622466 21.015267801473893 0.03835330614974734 0.06754502238207531 2.7367450259915886e-06 5.562765662569081 -0.305824577650211 RTS(ph)SEDNLYLAVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSSEDNLYLAVLR 14 1 Q15149-4 Q15149-4 PLEC Plectin 1 RT(0.181)S(0.736)S(0.083)EDNLYLAVLR 154.51 0.00013638 3452400.0 3209.2 1248.8 3632.9 5948.9 6122.5 4932.3 6213.5 4876.6 5535.1 4389.8 True False 3752.4541754107745 1372.7726109683183 3719.5221138499737 5615.602419594018 4922.840075733996 4673.641505182091 5624.912298155615 4748.5944171848005 5616.040366119594 5185.635990362321 0.7236246783200435 0.26472598800217806 0.7172740471492467 1.0829148883629327 0.9493223367168965 0.9012667903933503 1.084710208855713 0.9157207382103609 1.0829993421360842 1.0 12.340305223338735 -5.555189325545968 4.619262586726318 0.9935291411178487 0.4898964663624259 0.7422833785354122 0.12163877772883688 0.08196970266983197 4.147822747092724 0.030755622353899937 0.05738300271259859 2.78490685674031e-06 5.555189325545968 -0.5036326747554228 RTS(ph)SEDNLYLAVLR ddPTM_PC-9_Lapatinib_30min_R1 2 RTSSEDNLYLAVLR 14 1 Q15149-4 Q15149-4 PLEC Plectin 1 RT(0.089)S(0.455)S(0.455)EDNLYLAVLR;RT(0.001)S(0.782)S(0.217)EDNLYLAVLR 116.04 6.8905e-05 38721000.0 55627.0 41741.0 54711.0 44438.0 47595.0 47173.0 34018.6 36900.2 59397.0 32575.3 True False 54833.74877925758 41644.351279059396 50212.872770567395 47706.118760822326 44795.55567537029 45155.5207556339 35779.91665371182 38614.718002803005 52707.08438186133 38205.897201141146 1.4352168852514158 1.0899979932369066 1.314270216092913 1.2486585123146232 1.1724775219787882 1.1818992371231418 0.936502458386009 1.0107004633213965 1.3795536355127673 1.0 15.221507719543455 -6.6563585107503025 1.8756364579507978 1.0854176402737705 1.2609899342619297 0.25766633103203185 0.13788618977375802 0.5029890569041494 3.6348394567434306 0.05370209375440715 0.0530353492931957 2.206182773897664e-07 6.6563585107503025 0.1755722939881592 RTS(ph)SEELR ddPTM_PC-9_AZD4547_30min_R2 1 RTSSEELR 8 1 Q9P270 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 RT(0.018)S(0.866)S(0.116)EELR 84.31 0.0064508 28769000.0 16585.0 23915.0 28287.0 28012.0 20401.0 24786.0 24136.0 26312.0 25575.0 26881.0 True False 21858.685010569763 31645.056066685775 27911.895897602546 21554.26618108582 17568.67329689324 23236.127501755334 26284.057242372477 22246.084989609513 26926.842287602674 25939.90437193963 0.8426663682775676 1.2199372678072655 1.076021541844854 0.830930826576294 0.6772836570630566 0.8957676623854831 1.0132673145397226 0.8576008866738195 1.038047091520147 1.0 14.662885540620065 -4.487985542096818 18.38254089286021 0.9482366165148517 0.3803480098023595 0.0515585158410754 0.1425722881336659 58380085.16614241 813907019.665795 0.03867654420137967 1112204503.5551941 3.2509811990126657e-05 4.487985542096818 -0.5678886067124922 RTS(ph)SEELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSSEELR 8 1 Q9P270 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 RT(0.034)S(0.854)S(0.112)EELR 89.561 0.004645300000000001 28287000.0 43836.0 62536.0 66020.0 62165.0 53550.0 33199.0 30770.0 37311.0 33891.0 47893.0 True False 51256.568999534655 68744.16079397406 67594.16718224433 58682.09659164929 43057.261911891444 31457.985996500687 27855.242844491557 36331.625784272255 34386.591759527226 56575.621779220615 0.9059833084920762 1.2150844945591526 1.1947578313150888 1.0372329060853973 0.761056804287845 0.5560342954649548 0.4923541618896069 0.6421781085509222 0.6077987422518599 1.0 15.78789291468225 -6.312202305944335 2.727855128929972 0.6285357101584513 1.1161689381177051 0.6456883509821743 0.15013262878495265 0.15455503105211915 2.273433041584449 0.04773714067326088 0.0579609325518229 4.873014392265383e-07 6.312202305944335 0.4876332279592538 RTS(ph)SLDTITGPYLTGQWPR ddPTM_PC-9_AZD4547_30min_R2 1 RTSSLDTITGPYLTGQWPR 19 1 Q86VQ1;H7C0Q2;H7C2L5 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 RT(0.135)S(0.432)S(0.432)LDTITGPYLTGQWPR 89.20100000000001 0.0004909 8871700.0 3402.3 8298.3 2775.9 13763.0 10768.0 10961.0 3830.2 5206.4 2166.8 10175.0 True False 4484.160627763733 10980.563192898962 2739.0897522591604 10590.152986230325 9273.04906920966 10275.60693725248 4171.080379919415 4401.87051116992 2281.3326243901265 9818.776347028957 0.4566924094488195 1.1183229767955298 0.27896447127935403 1.078561381982672 0.9444200317298775 1.0465262242541815 0.42480653724041006 0.44831151618010656 0.23234388316426313 1.0 13.261327526302736 -7.279865421368257 24.262313354707782 0.4803913997355506 0.8268514326965021 0.16836852264322144 0.31356503496342775 875.7579978391584 1153140.010979385 0.12558305311686083 0.08486618447353175 5.249701121301004e-08 7.279865421368257 0.34646003296095146 RTS(ph)SLDTITGPYLTGQWPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSSLDTITGPYLTGQWPR 19 1 Q86VQ1;H7C0Q2;H7C2L5 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 RT(0.152)S(0.42)S(0.42)LDT(0.006)ITGPYLTGQWPR 57.693999999999996 0.011859 7786600.0 2146.1 1645.8 2111.8 3172.6 3758.2 3151.2 1574.7 2823.9 2275.4 2581.9 True False 2509.392342592878 1809.1841472867213 2162.153321046098 2994.8495077079792 3021.807688464434 2985.9455246294438 1425.533016159274 2749.7756171693723 2308.6734203661226 3049.9780316908473 0.8227575138309179 0.5931794027656473 0.7089078342795286 0.9819249439143318 0.9907637553668555 0.9790055841727144 0.467391240640834 0.9015722698976134 0.7569475571226458 1.0 11.574583135965542 -12.224900952690023 1.9404377188155744 5.586382476403043 0.8008851451952989 0.11512570554612245 0.16610921352231459 8859866.845822467 271573.09047091193 179624935.2748698 0.04505750286267349 5.95798008624495e-13 12.224900952690023 -4.785497331207744 RTS(ph)SLDTITGPYLTGQWPR ddPTM_PC-9_Lapatinib_30min_R1 1 RTSSLDTITGPYLTGQWPR 19 1 Q86VQ1;H7C0Q2;H7C2L5 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 RT(0.001)S(0.485)S(0.485)LDT(0.028)ITGPYLTGQWPR 100.62 0.00020069999999999997 6247300.0 10636.0 10466.0 12540.0 9537.9 10945.0 13911.0 9902.9 6348.0 9905.6 7551.2 True False 10484.328689596481 10441.76662002913 11509.009605799836 10239.348983501672 10301.23661869792 13316.05895812484 10415.623706738163 6642.95125451335 8789.927017407706 8856.414858658463 1.18381183096301 1.1790060410077503 1.2995111215401192 1.1561505583143707 1.1631384463236756 1.5035495932201517 1.1760541791417258 0.7500722764831728 0.9924926911948174 1.0 13.112507088140065 -7.626291911403425 6.466784819937862 0.9065436199784941 1.2466798237759913 0.6252421288011711 0.11559404777255487 0.133446859271946 7.270131528458198 0.055003037169552176 0.031369583555771186 2.3643299768853968e-08 7.626291911403425 0.3401362037974972 RTS(ph)STLDSEGTFNSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RTSSTLDSEGTFNSYR 16 1 Q92609;Q92609-2;C9JNM0;C9JED7;F2Z3C3;C9K0P2;C9J397;C9JWX0;C9JW04;C9JDR8 Q92609 TBC1D5 TBC1 domain family member 5 1 RT(0.024)S(0.478)S(0.478)T(0.02)LDSEGTFNSYR;RT(0.239)S(0.746)S(0.011)T(0.004)LDSEGTFNSYR 171.52 3.4354000000000003e-05 27663000.0 67859.0 63334.0 66223.0 73121.0 63850.0 60427.0 55890.0 66121.0 54474.0 49086.0 True False 79346.18842365709 69621.38096017572 67802.00747212603 69024.26743148059 51339.05085106013 57258.10174434606 50595.694591440806 64385.393810990514 55270.57919531689 57984.90323543781 1.3683939093850934 1.2006811613962687 1.1693044859767645 1.190383420167476 0.8853865055634683 0.9874656772618781 0.8725666814688924 1.1103820170150946 0.9531891252952537 1.0 15.823389713196374 -6.1461540507694075 4.88608737902265 0.9704207463506488 1.232274284454304 0.7310189734362618 0.07871914255869222 0.12544340401943072 4.5379922275046995 0.023732203667462187 0.03105334439570121 7.142429284521193e-07 6.1461540507694075 0.2618535381036552 RTS(ph)STLDSEGTFNSYR ddPTM_PC-9_Lapatinib_30min_R1 1 RTSSTLDSEGTFNSYR 16 1 Q92609;Q92609-2;C9JNM0;C9JED7;F2Z3C3;C9K0P2;C9J397;C9JWX0;C9JW04;C9JDR8 Q92609 TBC1D5 TBC1 domain family member 5 1 RT(0.018)S(0.979)S(0.002)T(0.002)LDSEGTFNSYR 218.64 4.483e-22 27005000.0 41747.0 40414.0 49026.0 39440.0 45395.0 33999.0 31061.0 28333.0 41698.0 33701.0 True False 41151.68012453784 40320.42386602875 44995.271525832744 42340.5491679831 42724.95535000388 32544.942025539993 32669.18659735976 29649.45461470175 37001.532140593845 39526.17294624022 1.0411248308939112 1.020094303611655 1.1383665093767381 1.0712028514769374 1.080928209470579 0.8233770081865643 0.8265203575816286 0.7501220686107948 0.9361273653009575 1.0 15.270520655001294 -6.758912333554527 24.999992834042462 0.8490676582979433 1.0713785728193062 0.6724055869615938 0.07031541485478715 35.782347675605216 353994.7211595368 0.023045451837405643 0.022034577970333133 1.742158509059256e-07 6.758912333554527 0.22231091452136287 RTS(ph)TPVIMEGVQEETDTR ddPTM_PC-9_Lapatinib_30min_R1 1 RTSTPVIMEGVQEETDTR 18 1 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 RT(0.055)S(0.89)T(0.055)PVIMEGVQEETDTR 147.78 5.6336000000000004e-05 3197600.0 8198.9 9263.0 9714.9 6636.9 8310.4 10488.0 9841.7 10418.0 11051.0 8655.1 True False 8081.9821825058825 9241.552092617027 8916.178422598476 7124.9997660493655 7821.598610875029 10039.452688722124 10351.25507019206 10902.058312778838 9806.320007810997 10151.122502804172 0.7961663530583238 0.9103970610209972 0.8783440865909605 0.7018927969868493 0.7705156359520212 0.9889992644605362 1.0197153139795727 1.07397564257226 0.9660330672890682 1.0 13.30935164781587 -6.833273329759019 5.721744363407264 1.0179176107926526 0.8148460597294457 0.7387766630818261 0.05897113273444853 0.1156271304494239 6.700303705339029 0.022911625374435703 0.020329517009371082 1.4680020776752175e-07 6.833273329759019 -0.20307155106320696 RTS(ph)VPSPEQPQPYR ddPTM_PC-9_AZD4547_30min_R2 2 RTSVPSPEQPQPYR 14 1 Q8TEH3 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 RT(0.002)S(0.997)VPS(0.001)PEQPQPYR;RT(0.026)S(0.929)VPS(0.046)PEQPQPYR 123.42 6.4041e-05 7524800.0 27253.0 23437.4 30596.0 45477.0 38269.0 28661.0 22601.1 33321.0 28603.0 27208.0 True False 35918.887102385124 31013.081206662824 30190.277048928754 34992.980262645964 32956.00992102382 26868.823139183776 24612.55411586778 28172.0050904066 30114.89618581816 26255.45620147066 1.3680541989734378 1.181205192881991 1.1498667864410481 1.332788887541245 1.2552061433683197 1.0233615037197015 0.9374262601648927 1.072996213595732 1.146995731277041 1.0 14.680329642969607 -6.760256276807789 24.99952809687585 1.0345475763025023 1.251401388555626 0.669388124559703 0.0776898745334398 20.670123052369675 436773.32783571916 0.027477070867913716 0.026027078006544923 1.7367756564511862e-07 6.760256276807789 0.21685381225312383 RTS(ph)VPSPEQPQPYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSVPSPEQPQPYR 14 1 Q8TEH3 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 RT(0.047)S(0.935)VPS(0.018)PEQPQPYR 110.22 0.0011045999999999999 0.0 6495.5 7012.6 5741.6 5517.3 6896.3 6126.4 6235.3 6335.2 5291.4 4582.0 True False 7595.05985802714 7708.764583341147 5878.501519139255 5208.183568327941 5545.0195205037735 5805.120799089177 5644.647244337286 6168.907712699245 5368.776714654692 5412.680328907957 1.403197565070223 1.424204666617812 1.086061093935928 0.9622189473322778 1.024449844356967 1.0725039068140196 1.04285620087158 1.139714030358017 0.9918887479796682 1.0 12.402127470143473 -5.294842706771809 4.672421920182119 1.0403230395341905 1.4178069143306193 0.9101294481200064 0.047119184462176396 0.04848035849160623 2.660907945527931 0.012609611027629617 0.029370715919994236 5.071743639542406e-06 5.294842706771809 0.37748387479642886 RTS(ph)VPSPEQPQPYR ddPTM_PC-9_Lapatinib_30min_R1 1 RTSVPSPEQPQPYR 14 1 Q8TEH3 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 RT(0.127)S(0.873)VPSPEQPQPYR 111.66 0.00055561 3782400.0 15031.0 12000.0 12849.0 10518.0 10105.0 11982.0 9705.4 8373.1 11452.0 10457.0 True False 14816.655183652198 11972.214737277802 11792.604818574328 11291.528807019435 9510.64376719438 11469.557791406212 10207.898123113082 8762.144793504367 10162.155165093789 12264.478516923351 1.208095000794953 0.9761698975425441 0.9615251722527052 0.9206692964106566 0.775462548535672 0.9351851181915111 0.8323140775229488 0.7144327238548114 0.8285843667198214 1.0 13.582198271655885 -1.5228787452866537 0.5852897411022967 0.8335185630242974 21.77424600330296 0.6394635231237049 0.0790853914997366 94.69281836344909 0.7721188836810507 0.03603915843279438 2524.2994157867797 0.0299999999995637 1.5228787452866537 20.94072744027866 RTSETSIS(ph)PPGSSIGSPNR ddPTM_PC-9_AZD4547_30min_R2 2 RTSETSISPPGSSIGSPNR 19 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 RT(0.004)S(0.004)ET(0.007)S(0.006)IS(0.978)PPGS(0.001)S(0.001)IGSPNR;RTSET(0.002)S(0.006)IS(0.991)PPGSSIGSPNR 78.758 0.0013755 18259600.0 31860.0 25740.6 47811.0 86043.0 59995.0 49920.0 49691.0 56498.0 46743.0 49984.0 True False 41990.81727083223 34060.74556513199 47176.994900847574 66207.11570109832 51665.72983908187 46798.49450849776 54113.4027357777 47767.53229488286 49213.7395522742 48234.07537394553 0.8705633298718585 0.7061552502264922 0.9780843632866868 1.3726212265460205 1.0711458536010416 0.9702372056618043 1.1218915738770021 0.990327521043045 1.0203106241953142 1.0 15.557765090403745 -5.513753980735787 24.94602956885917 1.0824580617391708 0.8017993611284836 0.49945858466524107 0.11467218603383528 331.24696879946856 905588.6161665703 0.03164995620582343 0.05889616834291486 3.0636984670103758e-06 5.513753980735787 -0.2806587006106872 RTSETSIS(ph)PPGSSIGSPNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSETSISPPGSSIGSPNR 19 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 RT(0.005)S(0.005)ET(0.012)S(0.122)IS(0.806)PPGS(0.027)S(0.014)IGS(0.01)PNR 46.22 0.040104 14309000.0 6183.4 7020.9 10342.0 11902.0 10950.0 9821.9 13599.0 9310.7 7862.3 8992.9 True False 7230.127492283117 7717.888552488362 10588.592502253414 11235.169526804626 8804.426105232711 9306.822273533237 12310.80427176604 9066.303990502101 7977.271263489741 10623.241582242772 0.6805952247540527 0.7265097468355761 0.996738370324998 1.0576027514600363 0.8287890317725342 0.8760812037909418 1.1588557199286613 0.8534404419134022 0.7509262781733318 1.0 13.37493643769163 -5.193856319863423 5.724735746952541 0.9406243602072032 0.6966011460430989 0.41082475184387446 0.1135853800427847 0.22170942317210096 13.856348529799767 0.03003570303165731 0.08213331180872435 6.3994651764484076e-06 5.193856319863423 -0.24402321416410433 RTSETSIS(ph)PPGSSIGSPNR ddPTM_PC-9_Lapatinib_30min_R1 2 RTSETSISPPGSSIGSPNR 19 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 RT(0.004)S(0.005)ET(0.002)S(0.014)IS(0.957)PPGS(0.007)S(0.007)IGS(0.004)PNR;RT(0.001)S(0.001)ET(0.002)S(0.014)IS(0.982)PPGSSIGSPNR 76.959 0.0016332 17356700.0 35641.0 25375.0 33910.0 26919.0 30765.0 28446.0 24606.0 23693.0 32194.0 18955.4 True False 35132.7528042411 25316.24574653536 31122.05069638537 28898.71305915155 28955.463186317178 27229.43089086474 25879.978281917352 24793.86327554896 28567.97270215068 22231.815633517137 1.5802916587376807 1.1387394607738681 1.3998879448003847 1.2998809245063756 1.3024335782392569 1.2247956415135566 1.1640964781526961 1.115242393345923 1.2850040308485207 1.0 14.440338155107659 -1.5228787815535993 0.08002173993440918 0.7977125187508287 2.4366931325994776 0.5187220773301149 0.10726428320650815 160.45858921682597 0.9396914364044391 2.906117308667672 29.087703103536843 0.029999997494331947 1.5228787815535993 1.638980613848649 RTSMGGT(ph)QQQFVEGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSMGGTQQQFVEGVR 16 1 A0A2R8Y6G0;A0A2R8Y804;A0A2R8Y543;A0A2R8Y5C3;A0A2R8Y750;A0A2R8Y5Z1;B4DGU4;A0A2R8YCH5;A0A2R8Y5A3;P35222 A0A2R8Y6G0 CTNNB1 Catenin beta-1 1 RT(0.165)S(0.053)MGGT(0.782)QQQFVEGVR 52.372 0.037852 95999000.0 90330.0 88288.0 67284.0 73171.0 116580.0 73273.0 68384.0 88404.0 66280.0 80578.0 True False 105621.08490117616 97052.6491649352 68888.3057359908 69071.46609358271 93736.98587653242 69430.43489025556 61906.17246271398 86083.48867178072 67249.21961055923 95186.15354490314 1.1096265682313808 1.0196088984639091 0.7237219193177442 0.725646152525734 0.9847754361910728 0.7294173816730859 0.6503695144431941 0.9043698633244139 0.706502123534544 1.0 16.538464103660687 -5.123375830901048 4.372797857488973 0.7958856389140692 1.0904952532230778 0.4549224613343026 0.11577230914286027 0.18170728398653602 5.492735471193525 0.028885525362702634 0.08679820199679644 7.527039049222447e-06 5.123375830901048 0.29460961430900867 RTSMGGT(ph)QQQFVEGVR ddPTM_PC-9_Lapatinib_30min_R1 1 RTSMGGTQQQFVEGVR 16 1 A0A2R8Y6G0;A0A2R8Y804;A0A2R8Y543;A0A2R8Y5C3;A0A2R8Y750;A0A2R8Y5Z1;B4DGU4;A0A2R8YCH5;A0A2R8Y5A3;P35222 A0A2R8Y6G0 CTNNB1 Catenin beta-1 1 RTS(0.002)MGGT(0.997)QQQFVEGVR 77.387 0.019666 41662000.0 54606.0 56314.0 37839.0 25668.0 33377.0 24957.0 15813.0 15830.0 40359.0 14947.0 True False 53827.308426486 56183.60839292183 34728.023482763936 27555.710345937907 31413.830481706762 23889.647287608488 16631.71976639676 16565.519590256197 35813.344420888934 17530.569034374425 3.0704826706389237 3.2048935937421916 1.9809980734035653 1.5718662806612784 1.7919458529902625 1.3627422612902642 0.9487267489027209 0.9449504780919585 2.0429082678756827 1.0 14.097585205638127 -5.409164043643669 1.1860979871824926 1.301477882726223 3.422459802929654 0.7951290593292387 0.3511300895062338 0.28740038946098745 0.6567451424059403 0.1182382080283932 0.5757185016143239 3.897947238688066e-06 5.409164043643669 2.120981920203431 RTSS(ph)EDNLYLAVLR ddPTM_PC-9_AZD4547_30min_R2 3 RTSSEDNLYLAVLR 14 1 Q15149-4 Q15149-4 PLEC Plectin 1 RT(0.001)S(0.029)S(0.97)EDNLYLAVLR;RTS(0.028)S(0.972)EDNLYLAVLR;RT(0.001)S(0.399)S(0.6)EDNLYLAVLR 193.3 7.617700000000001e-08 91292000.0 56436.0 52734.0 105888.0 190491.0 160404.0 116357.0 89904.0 129011.0 97030.0 125951.0 True False 74381.47405827645 69779.23423042468 104483.85593400997 146576.24300661215 138134.67337458258 109081.17839593915 97905.28183287426 109075.3143278545 102158.80770932902 121541.49382650082 0.6119842015802044 0.5741186160673144 0.859655847929264 1.2059769745454023 1.1365227547044003 0.8974809751116878 0.8055296899068313 0.8974327276539676 0.8405261815784462 1.0 16.89108940323134 -5.364241218367494 4.137176231056567 0.9659066890173018 0.5929408489908043 0.6056992113596974 0.11912595805941614 0.16333894104251498 4.799894954604959 0.036176298157606916 0.08141774810470712 4.322736683894195e-06 5.364241218367494 -0.37296584002649746 RTSS(ph)EDNLYLAVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RTSSEDNLYLAVLR 14 1 Q15149-4 Q15149-4 PLEC Plectin 1 RT(0.008)S(0.214)S(0.778)EDNLYLAVLR;RT(0.002)S(0.227)S(0.771)EDNLYLAVLR;RT(0.073)S(0.275)S(0.651)EDNLYLAVLR;RT(0.004)S(0.369)S(0.627)EDNLYLAVLR;RT(0.104)S(0.054)S(0.842)EDNLYLAVLR 206.13 4.0031e-11 95546700.0 46710.2 30623.199999999997 53536.1 77766.5 87057.5 93813.8 75572.4 89664.5 81765.7 63710.0 True False 54617.31429149702 33663.26891432176 54812.60366078985 73409.49512739468 69999.20782249267 88894.03917824365 68413.63517520486 87310.90188239083 82961.36867699314 75260.11867191736 0.7257139007392635 0.44729226459329124 0.7283087593807195 0.9754103025987757 0.9300969631424757 1.1811573081057827 0.9090290632338958 1.1601217673201745 1.1023284329200698 1.0 16.19959794383236 -5.729015604054812 2.145715739015943 1.0526658190776432 0.5790863415492459 0.7642854788897953 0.10487105569426367 0.13457547370161438 1.2617399394232047 0.03025831037208322 0.059973262337388505 1.8663126336441599e-06 5.729015604054812 -0.47357947752839735 RTSS(ph)EDNLYLAVLR ddPTM_PC-9_Lapatinib_30min_R1 2 RTSSEDNLYLAVLR 14 1 Q15149-4 Q15149-4 PLEC Plectin 1 RT(0.002)S(0.038)S(0.96)EDNLYLAVLR;RT(0.001)S(0.175)S(0.824)EDNLYLAVLR 175.19 5.4796e-05 36688000.0 61719.0 42337.0 54150.0 42415.0 48103.0 40868.0 39250.0 34601.0 54380.0 33363.0 True False 60838.875742121556 42238.971277677534 49697.99602504474 45534.3405922922 45273.676114136724 39120.17090796107 41282.17294827501 36208.688777160736 48255.15175321342 39129.750096596865 1.5547984741004708 1.079459264968602 1.2700821217196325 1.16367573214459 1.1570141900311854 0.999755194229144 1.0550073242574922 0.9253493489678541 1.2332087895805446 1.0 15.25597827599946 -1.5228787452803376 0.6217909359670923 1.0604301948357537 31.757683066312232 0.5901509357247439 0.10988290061216732 137.16223701901774 0.9831789105815686 0.04684893189006895 5755.685628754884 0.029999999999999995 1.5228787452803376 30.69725287147648 RTSS(ph)TLDSEGTFNSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RTSSTLDSEGTFNSYR 16 1 Q92609;Q92609-2;C9JNM0;C9JED7;F2Z3C3;C9K0P2;C9J397;C9JWX0;C9JW04;C9JDR8 Q92609 TBC1D5 TBC1 domain family member 5 1 RT(0.003)S(0.339)S(0.646)T(0.012)LDSEGTFNSYR;RT(0.046)S(0.309)S(0.563)T(0.082)LDSEGTFNSYR 132.62 2.7325e-06 31320900.0 71410.0 70279.0 85556.0 81761.0 93054.0 79173.0 78895.0 82097.0 65629.5 67161.0 True False 83498.30258820996 77255.8346622699 87595.9795129367 77180.19624273844 74820.73669372842 75021.02850389907 71421.494449664 79942.0407389616 66589.20727868445 79336.75765381647 1.0524541846359825 0.9737710103981484 1.1041033450744115 0.972817626093467 0.943077823021284 0.9456024007339832 0.9002320810904513 1.00762928941193 0.8393235273017386 1.0 16.275701817966052 -5.96989588751165 9.411203145420435 0.9398290126603062 1.0369666291656932 0.42920466444937166 0.053546571714045144 0.2990661428948935 87.76474126185173 0.014076378456934836 0.020809234965295176 1.0717762090638034e-06 5.96989588751165 0.09713761650538699 RTSS(ph)TLDSEGTFNSYR ddPTM_PC-9_Lapatinib_30min_R1 1 RTSSTLDSEGTFNSYR 16 1 Q92609;Q92609-2;C9JNM0;C9JED7;F2Z3C3;C9K0P2;C9J397;C9JWX0;C9JW04;C9JDR8 Q92609 TBC1D5 TBC1 domain family member 5 1 RT(0.008)S(0.057)S(0.704)T(0.226)LDS(0.004)EGTFNSYR 74.78 0.018919 21061000.0 23565.0 24760.0 30015.0 22472.0 29497.0 24557.0 19625.0 16997.0 26284.0 22342.0 True False 23228.958778708267 24702.669741249872 27547.282561250548 24124.66584439442 27762.044453333263 23506.754355162953 20641.086474137504 17786.74267059914 23323.619137209684 26203.784931156315 0.8864734174752374 0.9427138028399242 1.0512711287176233 0.9206557719724748 1.0594669635043514 0.8970747705692473 0.7877139324859609 0.6787852486703435 0.8900858863895608 1.0 14.677487592343741 -7.018344090776576 5.369645180315036 0.8151504912369598 0.9730069116415575 0.30638483494391777 0.09164698113007465 0.18398151576828567 16.38308813580374 0.033591318842420934 0.027279304410201283 9.586408010794161e-08 7.018344090776576 0.15785642040459769 RTSSTENK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSSTENK 8 1 Q9Y2K7-5 Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 0 89.14200000000001 0.023596000000000002 17375000.0 30142.0 36389.0 38168.0 33160.0 37622.0 35807.0 33922.0 42043.0 35890.0 24928.0 False True 35244.4452683633 40001.459433477045 39078.06987294604 31302.1527061705 30250.239171786765 33929.21788537907 30708.66258598776 40939.41579824069 36414.82335279076 29447.24907006057 1.1968671567422173 1.3584107411291972 1.3270533277988694 1.0629907273068788 1.0272687645564353 1.1522033112381753 1.0428363788048944 1.3902628289942496 1.2366120606428468 1.0 14.845845244900467 -5.750266605924302 24.990794432192114 1.1395455605572997 1.3005404844680613 0.29251040692563635 0.11598866829731538 301.51555505548504 674411.4312712954 0.033410451950131856 0.057191440813779165 1.777188089853123e-06 5.750266605924302 0.16099492391076153 RTSSTENK ddPTM_PC-9_Lapatinib_30min_R1 1 RTSSTENK 8 1 Q9Y2K7-5 Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 0 82.305 0.037622 5547100.0 31404.0 22170.0 22300.0 29371.0 22917.0 29785.0 24556.0 21943.0 30631.0 28443.0 False True 30956.17320121173 22118.666727120726 20466.58008048935 31531.041318783788 21569.067116555543 28511.164982226186 25827.389526569226 22962.551886859856 27181.014221270325 33359.334652084784 0.9279613494712531 0.663042802196249 0.6135188334522222 0.9451939508875445 0.6465676651379972 0.8546682743999029 0.7742177653101109 0.6883396244662456 0.8147948544163082 1.0 15.025802894239995 -8.550364250458411 19.431452787554292 1.000000007042694 0.7606523021864402 0.2927074702231782 0.10976851193260413 420.6042721404769 297356.4083870116 0.1007865235143764 0.026022968476475145 2.816020094698147e-09 8.550364250458411 -0.23934770485625378 RTST(ph)PVIMEGVQEETDTR ddPTM_PC-9_AZD4547_30min_R2 1 RTSTPVIMEGVQEETDTR 18 1 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 RT(0.151)S(0.151)T(0.698)PVIMEGVQEETDTR 79.332 0.0018829 7686500.0 7724.2 9950.3 12589.0 16628.0 10767.0 17355.0 11699.0 18699.0 12005.0 13796.0 True False 10180.334926659203 13166.539886278217 12422.061634493528 12794.67150003908 9272.187901948408 16269.789106469932 12740.188336033956 15809.499210273189 12639.55979130675 13313.006239175587 0.7646909153172322 0.9889982510136313 0.9330771285857047 0.9610655377287192 0.6964758924745003 1.22209730951628 0.9569730613168327 1.1875228574408148 0.949414397036252 1.0 13.700548765722619 -6.767919064495487 24.999999847115895 1.0682823915716773 0.884225782476865 0.40311692537766863 0.11741634837928251 163.07324704158572 629167.2254173752 0.03883263625965704 0.03505600223665805 1.7064003656573283e-07 6.767919064495487 -0.18405660909481225 RTST(ph)PVIMEGVQEETDTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RTSTPVIMEGVQEETDTR 18 1 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 RT(0.193)S(0.074)T(0.733)PVIMEGVQEETDTR;RT(0.017)S(0.017)T(0.965)PVIMEGVQEETDTR 77.027 0.0023640999999999996 8603400.0 19100.8 22266.9 29556.0 25863.0 29570.0 31129.0 27692.0 23897.0 27524.0 21906.6 True False 22334.188182003658 24477.41067518452 30260.727131754196 24413.979958977332 23775.970770021107 29496.540440527406 25068.813287281795 23269.729070964433 27926.486429707787 25878.093167449806 0.8630538593970374 0.9458738136847308 1.1693569126575751 0.9434226780544218 0.9187682653499057 1.139826657615909 0.9687272213245625 0.899205707329076 1.079155494533674 1.0 14.65944369551918 -5.001215041839965 18.768415344432142 1.0113523270712292 0.8837559584816568 0.23176474641937694 0.08614280825135251 2.8615777617925544 44458.21239510951 0.021352717128396006 0.07601151021068771 9.972061727914798e-06 5.001215041839965 -0.12759636858957246 RTST(ph)PVIMEGVQEETDTR ddPTM_PC-9_Lapatinib_30min_R1 1 RTSTPVIMEGVQEETDTR 18 1 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 RT(0.298)S(0.298)T(0.403)PVIMEGVQEETDTR 81.312 0.0027004 2562700.0 10543.0 7261.3 9679.7 11579.0 9562.1 9916.0 10733.0 12681.0 11575.0 12379.0 True False 10392.654886650596 7244.486905982942 8883.87243072254 12430.55828641168 8999.676077811913 9491.915795325 11288.702223027667 13270.205554266497 10271.301609846369 14518.693656019324 0.7158119823226583 0.49897649730900134 0.61189199532696 0.8561760844962851 0.6198681707207677 0.6537720279943874 0.7775287839582915 0.9140082343954399 0.7074535666360021 1.0 13.825624029799943 -8.590862388202067 0.16477934703498925 1.1619823974273247 0.4908333030017115 0.5059182296045805 0.10200698179094038 5.000489324726125 0.5754572420747319 1.1927817579741693 0.7758947366136886 2.565296755054606e-09 8.590862388202067 -0.6711490944256131 RTSVPS(ph)PEQPQPYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTSVPSPEQPQPYR 14 1 Q8TEH3 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 RT(0.008)S(0.464)VPS(0.528)PEQPQPYR 132.65 1.8516e-05 2045700.0 8589.9 7489.3 6357.6 5985.3 7323.2 6212.8 5859.9 6256.7 5648.8 4903.9 True False 10044.00041174156 8232.7882089406 6509.189295332265 5649.963045604415 5888.271530031067 5886.989830990674 5304.807849997925 6092.468254521626 5731.4030135203275 5792.938250748959 1.7338352278212161 1.421176586488937 1.1236420989798577 0.9753190524469929 1.016456809162394 1.0162355571854327 0.91573699224432 1.0517060584469273 0.9893775430420519 1.0 12.50007957148899 -4.988716438102051 1.4422447582692857 0.9920749641984157 1.8784789567107847 0.9783862807588485 0.03563723886181879 0.1025784486899598 0.2601744359031805 0.010509668170062561 0.11799664155978407 1.0263218191159879e-05 4.988716438102051 0.886403992512369 RTTSSSGVS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 RTTSSSGVSPR 11 1 Q5QP82-2 Q5QP82-2 DCAF10 DDB1- and CUL4-associated factor 10 1 RTTSSSGVS(1)PR 80.318 0.023946000000000002 1138600.0 1076.5 1993.0 3563.4 4057.5 4066.4 3287.5 692.73 3021.2 1879.2 2660.3 True False 1418.8046074090043 2637.198274760808 3516.1469877158024 3122.1060627500947 3501.8505511733074 3081.932105302212 754.3816280041718 2554.342960269391 1978.530675537165 2567.163706732299 0.5526739894648081 1.0272809123332671 1.369662160030865 1.2161694458995655 1.3640931982599411 1.2005202851769643 0.2938580138172847 0.9950058710984087 0.770706858447919 1.0 11.32595958344265 RTTTTS(ph)PTTTR ddPTM_PC-9_Lapatinib_30min_R1 1 RTTTTSPTTTR 11 1 Q96H15-2;Q96H15 Q96H15-2 TIMD4 T-cell immunoglobulin and mucin domain-containing protein 4 1 RTTTT(0.039)S(0.617)PT(0.115)T(0.115)T(0.115)R 63.602 0.018384 5798800.0 8978.9 6330.9 10545.0 7863.0 5569.1 7742.3 7104.9 5515.9 6702.5 6840.2 True False 8850.859239471407 6316.2411900193365 9678.030804877137 8441.271250199065 5241.536487271872 7411.179877182804 7472.7569574573035 5772.1888507829535 5947.593869546032 8022.519456006417 1.1032518260637953 0.7873139136222849 1.2063580347731344 1.0521970431469791 0.6533529168754538 0.9237970587449424 0.9314725876872122 0.7194982676497402 0.7413623490926033 1.0 12.969839667960063 -6.229221771326102 24.694646185966185 0.8241608506078848 1.0315025077509092 0.349058106138458 0.13968771016840234 666.8223432080096 511115.95579532534 0.040891875963506026 0.05278658407025186 5.898997724920921e-07 6.229221771326102 0.20734165714302444 RTVS(ph)VPSEGQFPEYPPEGATK ddPTM_PC-9_AZD4547_30min_R2 1 RTVSVPSEGQFPEYPPEGATK 21 1 Q9UJF2-2 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 RT(0.263)VS(0.538)VPS(0.199)EGQFPEYPPEGATK 91.809 0.00018843 7733900.0 55562.0 44477.0 72317.0 89374.0 81016.0 72557.0 61216.0 77940.0 60978.0 74949.0 True False 73229.56023860571 58853.32045486024 71358.02932891165 68770.20511453539 69768.32683795423 68019.99931997333 66664.10540889429 65896.16388302535 64201.17259094571 72325.05832270005 1.0125060654893627 0.8137334669302084 0.9866294059594988 0.9508489410087496 0.9646494376355953 0.9404762456807376 0.921729023866836 0.9111111060430779 0.8876753656318234 1.0 16.142207961089547 -7.2450125655970945 7.367999680358292 0.922701747993406 0.9419588808366736 0.007855267983691072 0.05598834026329736 0.8565161758742884 263.20186479807074 0.021211960737439497 0.01583194917378995 5.688364722572686e-08 7.2450125655970945 0.019257132843267577 RTVS(ph)VPSEGQFPEYPPEGATK ddPTM_PC-9_Lapatinib_30min_R1 1 RTVSVPSEGQFPEYPPEGATK 21 1 Q9UJF2-2 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 RT(0.241)VS(0.593)VPS(0.166)EGQFPEYPPEGATK 108.05 2.687e-05 8175800.0 44128.0 32344.0 32086.0 29746.0 27452.0 32666.0 27692.0 25554.0 35720.0 31150.0 True False 43498.726627915916 32269.109455209422 29448.012935541752 31933.620069747118 25837.327332708595 31268.951328165196 29125.756262003382 26741.33212946346 31696.83745172459 36534.23599523401 1.1906291576369747 0.8832567200644079 0.8060388327097718 0.8740738433373273 0.7072086394821324 0.8558808053970066 0.7972181563014733 0.7319526849542423 0.8675927274313202 1.0 15.156961417536719 -4.745351410057064 2.8817141923184932 0.8177095656508243 1.2764653458318145 0.6539708919152263 0.07782330519183529 0.2615152920890649 2.805784070056806 0.018510840454186085 0.2965845101940227 1.797415944648708e-05 4.745351410057064 0.45875578018099017 RTYPEER ddPTM_PC-9_Lapatinib_30min_R1 1 RTYPEER 7 1 H0YIQ2;P49750-3;P49750-1;P49750;F8VU51;H0YI23 H0YIQ2 YLPM1 YLP motif-containing protein 1 0 79.71300000000001 0.045811000000000004 0.0 13371.0 4285.7 5741.8 4904.8 4290.9 3684.7 2215.1 2925.7 4611.9 3089.4 False True 13180.327088058904 4275.776724962623 5269.731367988954 5265.515353933152 4038.517698233982 3527.1139704552224 2329.7870394324596 3061.6387027929577 4092.459256539999 3623.398673633258 3.637559174476021 1.1800458933974305 1.4543614552645634 1.4531979029106696 1.1145662020636762 0.9734269640603779 0.6429839080048934 0.8449632454391193 1.129453208204772 1.0 11.823127835369243 -3.1360362880510815 1.354443424776212 1.0311946832464818 199.99999998757187 0.8979670006972282 0.2556642131231449 35.093460834438694 1.0903045347703035 0.08043099732333574 20840.24940218795 0.0007310779947404021 3.1360362880510815 198.9688053043254 up RTYS(ph)LTTPAR ddPTM_PC-9_AZD4547_30min_R2 1 RTYSLTTPAR 10 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 RT(0.003)YS(0.73)LT(0.264)T(0.003)PAR 84.169 0.0058291 3654700.0 7250.4 7480.4 9426.4 17299.0 12268.0 9598.5 6731.3 10787.0 10884.0 11450.0 True False 9555.876382311422 9898.293012805201 9301.399776899656 13310.982816885744 10564.799961094366 8998.304277640544 7330.372659744024 9120.117010600401 11459.306019873613 11049.138985108762 0.8648525821957844 0.895842927321795 0.8418212305443361 1.2047077002855455 0.9561649984974255 0.8143896361307259 0.6634338358512255 0.8254142719076881 1.0371220812153457 1.0 13.431646330133434 -6.751109020447293 23.81714447534517 0.844370477369378 0.957363392654317 0.07593951068669214 0.1349976460959289 254.23899115853266 586158.2171908407 0.04700024695043504 0.046448955465134834 1.7737441640291161e-07 6.751109020447293 0.11299291528493904 RTYS(ph)LTTPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RTYSLTTPAR 10 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 RT(0.013)YS(0.987)LT(0.001)TPAR 104.94 0.0011611 2366200.0 5190.8 6749.6 8370.3 9233.3 10339.0 8121.2 8296.1 10821.0 8694.5 4871.7 True False 6069.499917026749 7419.655681447596 8569.879696539525 8715.988135762493 8313.147169132506 7695.309975444482 7510.233349437325 10536.960215797224 8821.640614122014 5754.900645644019 1.0546663254075213 1.2892760689211304 1.489144682806333 1.514533207859943 1.4445335690416943 1.3371751224357262 1.305015292509341 1.8309543230381964 1.5328919050582153 1.0 12.49057530610839 -4.893626975933096 2.4753595373166233 1.4565790455722014 1.0143275883251381 0.24563843141768715 0.19935616047389432 0.5367648964719816 5.030023718735921 0.05167598459916563 0.4610908437514529 1.277535638170349e-05 4.893626975933096 -0.4422514572470633 RVAAPQDGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 RVAAPQDGSPR 11 1 Q9HD15 Q9HD15 SRA1 Steroid receptor RNA activator 1 1 RVAAPQDGS(1)PR;RVAAPQDGS(1)PR 88.78 0.0044198 2243000.0 13727.400000000001 14216.1 15360.1 21737.0 16524.3 15996.599999999999 14590.2 19249.4 13086.6 14621.8 True False 18092.4276523422 18811.176314012602 15156.415037888948 16725.87048330223 14230.186175180284 14996.330073209847 15888.699535037396 16274.847537206953 13778.330959176585 14109.895232529536 1.2822510269694398 1.3331903606657929 1.0741692116144648 1.185400047814793 1.0085252895693673 1.0628236302305554 1.1260678604052943 1.1534350375392048 0.9765012944540828 1.0 13.784419655360514 -5.2641630054561075 24.922860924408145 1.0820363866319906 1.307720706655364 0.6713677906166653 0.06536094006763568 119.33423659220075 1091995.1703549603 0.01659916567862726 0.03721360026409232 5.442983208687927e-06 5.2641630054561075 0.22568432002337335 RVAFISLS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 2 RVAFISLSPVR 11 1 Q6ZU65-2;Q6ZU65 Q6ZU65-2 UBN2 Ubinuclein-2 1 RVAFISLS(1)PVR;RVAFIS(0.001)LS(0.999)PVR 113.37 0.00072058 11551000.0 26094.0 20964.9 35831.0 72377.0 56316.0 47582.0 35074.0 47170.0 28852.0 47122.0 True False 34391.34921108276 27741.393934035576 35355.85752844049 55691.600863503045 48497.495484919324 44606.690018095745 38195.51805265875 39880.96035876711 30377.057817474586 45472.27312282052 0.7563147133241347 0.6100727328740774 0.7775256238663149 1.2247375606906683 1.0665289450986468 0.9809645956693909 0.8399738000669711 0.8770390750215787 0.6680347326254443 1.0 15.472699504613896 -5.534013056417644 24.98283755252445 0.9514848579922208 0.6858450261883747 0.3811556419920231 0.14147552328920282 218.4248580916212 490093.6563739513 0.04139194362250676 0.07177275236372764 2.9240644688728123e-06 5.534013056417644 -0.2656398318038461 RVAFISLS(ph)PVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RVAFISLSPVR 11 1 Q6ZU65-2;Q6ZU65 Q6ZU65-2 UBN2 Ubinuclein-2 1 RVAFIS(0.004)LS(0.996)PVR;RVAFISLS(1)PVR 102.63 0.0014850999999999998 12991700.0 27521.0 13386.3 28237.0 42076.0 41768.0 43569.0 37486.0 42721.0 37158.0 25666.0 True False 32179.761735472985 14715.203397025307 28910.27716941884 39718.61813223254 33583.86023409678 41284.164941159004 33935.054704862225 41599.61901664107 37701.365453970415 30319.042628055788 1.061371301536262 0.48534525240610876 0.953535292129134 1.310022173836018 1.1076820810634662 1.3616579338477073 1.1192653779067665 1.3720624205378693 1.2434879925622513 1.0 14.8879365783895 -5.573530374905677 4.810751305064989 1.2269464529155805 0.759467070876528 0.5282130319831726 0.1707988061703882 0.12371136491121407 6.158129634248895 0.043061743080656245 0.0784453998444279 2.6697440365525265e-06 5.573530374905677 -0.4674793820390525 RVAFISLS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 2 RVAFISLSPVR 11 1 Q6ZU65-2;Q6ZU65 Q6ZU65-2 UBN2 Ubinuclein-2 1 RVAFISLS(1)PVR;RVAFIS(0.003)LS(0.997)PVR 101.75 0.0016515999999999998 11776700.0 56003.0 29487.0 44973.0 38767.0 33302.0 31259.0 25757.0 25717.0 34696.0 27001.0 True False 55204.38695030758 29418.724663175868 41275.4935408003 41618.05450292094 31343.241834251112 29922.125438288003 27090.571430031083 26911.90570452423 30788.171114922636 31668.086873429023 1.7432182490514319 0.9289706947172589 1.303378183398642 1.3141954128539541 0.989742195653427 0.9448668483789603 0.8554533634540871 0.8498115409398018 0.9722144327182367 1.0 14.950742093723733 -6.350364254077607 3.3881445117278517 0.9143316761173258 1.2951353113800543 0.5017675739060434 0.1886378132280974 0.21872768316019062 4.799017095247222 0.058719887670441395 0.06843912959331103 4.4630910407276e-07 6.350364254077607 0.38080363526272853 RVEDVLGK ddPTM_PC-9_Lapatinib_30min_R1 1 RVEDVLGK 8 1 Q14204 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 80.755 0.011928 3786500.0 26715.0 20620.0 23660.0 19478.0 24035.0 26084.0 25196.0 28148.0 25797.0 21242.0 False True 26334.039201069012 20572.25565688903 21714.766130241158 20910.47709670323 22621.308554628093 24968.448124773826 26500.52559502517 29455.858839326058 22891.470205547026 24913.651396814173 1.0570124299176984 0.8257422940227742 0.8716011067337134 0.8393180414885774 0.9079884836760936 1.0021994659508906 1.0636949667849136 1.1823180139340281 0.918832404007799 1.0 14.604648861024769 -6.857241318251798 2.8760578172684177 1.054708410476411 0.8893817518109255 0.37804980277810396 0.08541417055352164 0.2459061505442778 4.108258257014234 0.031818152233893456 0.02797590957908623 1.389180510495773e-07 6.857241318251798 -0.16532665866548557 RVELLK ddPTM_PC-9_Lapatinib_30min_R1 1 RVELLK 6 1 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;A0A3B3IU45;A0A3B3IRR8;E5RG31 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 0 76.035 0.038398 1839900.0 14752.0 13191.0 13428.0 11272.0 14651.0 12685.0 13226.0 10340.0 12412.0 14373.0 False True 14541.63377481453 13160.457049952622 12324.001673578956 12100.980482289691 13789.256984974269 12142.492120179266 13910.777564684988 10820.434148025843 11014.029855845627 16857.35389918134 0.8626284920980825 0.7806953053641322 0.7310756923823886 0.717845787343728 0.8179965294341913 0.7203083113043591 0.8252052871335014 0.6418821253169115 0.6533664726811312 1.0 14.041090473591538 -4.80658611108927 3.117565219815023 0.7517428715688389 0.876206409043056 0.07377328539665895 0.0978666732980008 0.7642686780861826 11.477656143963713 0.023568244282707207 0.22956134952039361 1.5610394873221535e-05 4.80658611108927 0.12446353747421712 RVGDPPQPLPEEPMEVQGAERAS(ph)PEPQR ddPTM_PC-9_Lapatinib_30min_R1 2 RVGDPPQPLPEEPMEVQGAERASPEPQR 28 2 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 RVGDPPQPLPEEPMEVQGAERAS(1)PEPQR;RVGDPPQPLPEEPMEVQGAERAS(1)PEPQR 69.27 0.00047069 25947000.0 43568.1 48772.3 49692.8 37729.7 54320.4 56633.0 50998.3 45870.8 55270.8 38037.0 True False 42946.810904589 48659.37073591116 45607.249803755214 40504.468000589564 51125.38087001543 54210.93860797102 53638.74243740164 48002.12482758839 49045.6204766736 44611.64476888337 0.9626816300336097 1.0907324979385444 1.022317155980904 0.9079348723955014 1.1460097724456775 1.215174622877459 1.2023484611536823 1.075999889182967 1.099390545467692 1.0 15.445132718787773 -6.288953183652488 24.911075813138755 1.1355146584555893 1.004574859830691 0.41541065375684594 0.0727777848899145 689.7420294005211 624492.2251703609 0.023127844095386527 0.026230241259807396 5.140990677675263e-07 6.288953183652488 -0.13093979862489835 RVHNNS(ph)PDTSR ddPTM_PC-9_AZD4547_30min_R2 1 RVHNNSPDTSR 11 1 Q9BRD0 Q9BRD0 BUD13 BUD13 homolog 1 RVHNNS(0.993)PDT(0.003)S(0.003)R 69.26100000000001 0.016117 2503100.0 3437.0 2045.7 1003.5 1809.9 2627.6 1040.7 1042.3 2642.0 3846.7 4431.1 True False 4529.894505958896 2706.932519156139 990.1929343247479 1392.6555176762536 2262.8030956775 975.6248644830454 1135.06268079735 2233.739607120262 4050.0287088063033 4275.968537721872 1.0593844332569176 0.6330571647747258 0.2315716136799027 0.3256935838957845 0.5291907729711838 0.2281646499211226 0.2654515978740299 0.5223938360197435 0.9471605492598073 1.0 12.062035522510103 -8.249746724007723 3.926707734825574 0.9951238809752975 0.44917369730479134 0.4170620688168365 0.23634093451340643 0.21371506557457462 7.3273861776965 0.21396947416600415 0.06443363199916216 5.6266937240779435e-09 8.249746724007723 -0.5459501836705061 RVHNNS(ph)PDTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVHNNSPDTSR 11 1 Q9BRD0 Q9BRD0 BUD13 BUD13 homolog 1 RVHNNS(0.965)PDT(0.018)S(0.018)R 54.402 0.040907 979600.0 522.82 667.99 1034.5 910.56 2631.6 3340.6 854.35 858.4 2203.1 2564.5 True False 611.3230998343082 734.3036326078854 1059.1664033630968 859.5442752753505 2115.956871098666 3165.4130552098 773.4197830416433 835.8679095499807 2235.316169644284 3029.4235494291684 0.20179518969854818 0.24239054745126334 0.34962638471687946 0.28373195799488443 0.6984684830542675 1.0448895651472228 0.2553026245496039 0.27591648903220634 0.7378684865856683 1.0 11.564827582816115 -6.2526790501307845 22.083699888052273 0.6306722842338391 0.27318907402933573 0.38288094820530594 0.24552389023412563 168.45304388897748 424645.36708471976 0.07692561965112946 0.09743512229634554 5.588830647836914e-07 6.2526790501307845 -0.3574832102045034 RVHNNS(ph)PDTSR ddPTM_PC-9_Lapatinib_30min_R1 1 RVHNNSPDTSR 11 1 Q9BRD0 Q9BRD0 BUD13 BUD13 homolog 1 RVHNNS(0.975)PDT(0.02)S(0.005)R 57.53 0.034812 3174500.0 793.19 851.89 900.03 2475.6 2118.9 965.6 3305.3 3049.0 2274.1 2951.1 True False 781.878965146769 849.9175010449659 826.0330076162697 2657.6638823595085 1994.2704679176832 924.3035389235389 3476.4322610428903 3190.667670921738 2017.9669106653678 3461.1937029064243 0.22589864430014758 0.2455561791676887 0.23865552711558313 0.7678460411296317 0.576179965381036 0.267047619480928 1.0044026886226187 0.9218402507327109 0.5830262862696318 1.0 11.757053967686003 -6.046930741181847 0.35161810423997125 0.9534013131015249 1.841054648588355e-18 0.5623687985569292 0.2050001896135986 2.1708275726632547 0.40919691650670137 0.22991691618194351 0.8181604563319963 8.975719227618455e-07 6.046930741181847 -0.9534013131015249 RVHPVSTMIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVHPVSTMIK 10 1 P00338-3;P00338;P00338-4 P00338-3 LDHA L-lactate dehydrogenase A chain 0 53.756 0.034634 4503900.0 39752.0 41764.0 43715.0 49287.0 52115.0 51118.0 39247.0 44479.0 39256.0 34841.0 False True 46481.22846221149 45910.05391133958 44757.33139006074 46525.609180609965 41903.439860657745 48437.28209190403 35529.24003632632 43311.47337939603 39830.04473494438 41157.39749879574 1.1293529544372072 1.115475144235806 1.0874674811829472 1.1304312713643105 1.0181265679367564 1.1768791283103188 0.8632528341318447 1.0523375143110865 0.9677493514041989 1.0 15.328864138888076 -7.250213266263171 24.989143233042338 0.9751963796354804 1.1056680940168844 0.5790070383992088 0.057869649234312856 531.421789680615 1182937.793704527 0.020948076523652288 0.016067315854769407 5.620652475595838e-08 7.250213266263171 0.13047171438140392 RVNDAEPGS(ph)PEAPQGK ddPTM_PC-9_Lapatinib_30min_R1 2 RVNDAEPGSPEAPQGK 16 1 Q8N8A6 Q8N8A6 DDX51 ATP-dependent RNA helicase DDX51 1 RVNDAEPGS(1)PEAPQGK;RVNDAEPGS(1)PEAPQGK 191.41 2.1286e-08 66250100.0 132413.0 80823.0 98528.0 92641.0 94593.0 77247.0 72991.0 82593.0 81584.0 68046.0 True False 130524.76633843002 80635.85930925037 90427.40816907877 99454.12818131632 89029.22571699347 73943.32588155205 76770.11683229402 86430.57230057042 72395.1508023936 79807.66043440443 1.6354917012723489 1.010377435829317 1.1330667717468417 1.2461727062286174 1.1155473701696648 0.9265191521599309 0.9619391974958715 1.0829859167668434 0.9071203241435285 1.0 16.284239611464557 -4.759049790741138 24.999897918914698 1.0505442772119415 1.6354924638658268 0.7625434270136444 0.09916147040174515 33.69137878413398 352402.9132403368 0.026827873433296734 0.17539640827033967 1.7416071911771213e-05 4.759049790741138 0.5849481866538853 RVNNGNTAPEDS(ph)SPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVNNGNTAPEDSSPAK 16 1 E9PJ27;G3V167;Q9UGN5-2;Q9UGN5 E9PJ27 PARP2 Poly [ADP-ribose] polymerase 2 1 RVNNGNTAPEDS(0.5)S(0.5)PAK 78.78 0.032159 0.0 8224.9 6231.5 8744.4 6930.9 9982.5 9054.7 6716.5 7398.4 6446.4 6083.9 True False 9617.21312082017 6850.122137451214 8952.89965932167 6542.584143280976 8026.500784975846 8579.855592111644 6080.26449675098 7204.199839252766 6540.666404609369 7186.862909874101 1.3381656560621167 0.9531449567571081 1.24573124207242 0.9103532689196082 1.1168295382326214 1.1938248578978314 0.8460248335052064 1.0024123083459469 0.9100864294521444 1.0 12.811146451432172 -7.258709441290333 24.99770442297257 0.9398319185582404 1.1136457983770394 0.3427180528089586 0.12593808223834985 290.6018062043251 2661025.1228918857 0.04686495588232745 0.03467191367445712 5.511763299687756e-08 7.258709441290333 0.17381387981879892 RVNNGNTAPEDS(ph)SPAKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVNNGNTAPEDSSPAKK 17 2 E9PJ27;G3V167;Q9UGN5-2;Q9UGN5 E9PJ27 PARP2 Poly [ADP-ribose] polymerase 2 1 RVNNGNTAPEDS(0.5)S(0.5)PAKK 42.528999999999996 0.043 4822300.0 41166.0 38123.0 28829.0 44023.0 27602.0 25172.0 34928.0 42357.0 31884.0 31367.0 True False 48134.59073443849 41907.59949387025 29516.392694591348 41556.53403449172 22193.58624261491 23851.936007226566 31619.366983178483 41245.17363095121 32350.24318139817 37053.588798964636 1.2990534060167334 1.130999745294341 0.7965866101319747 1.1215252120370296 0.598959155158408 0.6437145977043132 0.8533415522779807 1.1131222364108413 0.8730663946457492 1.0 15.177325660048908 -5.0493060598296235 2.8304379168938083 0.8682203362194933 1.2974130094769192 0.41764670149437344 0.16517322342753687 0.2892986223903278 4.274350086866401 0.04616092643028276 0.21349178638627872 8.926761674053052e-06 5.0493060598296235 0.4291926732574258 RVNNGNTAPEDS(ph)SPAKK ddPTM_PC-9_Lapatinib_30min_R1 1 RVNNGNTAPEDSSPAKK 17 2 E9PJ27;G3V167;Q9UGN5-2;Q9UGN5 E9PJ27 PARP2 Poly [ADP-ribose] polymerase 2 1 RVNNGNTAPEDS(0.5)S(0.5)PAKK 54.658 0.017531 7166000.0 69366.0 48392.0 54427.0 46181.0 48434.0 52701.0 36867.0 34565.0 43488.0 29581.0 True False 68376.82811983362 48279.95129719564 49952.22215429568 49577.304795299926 45585.207344907736 50447.10108203129 38775.79286838361 36171.0160857363 38589.9234910582 34694.03643579511 1.970852490639767 1.391592223249741 1.4397927507437025 1.428986358708876 1.313920547390554 1.4540568427484315 1.117650087793682 1.042571571419039 1.112292700864393 1.0 15.082400078551844 -1.5228787452804213 0.21365516054297298 0.9708051340410874 5.203324479933409 0.7819077372470594 0.12668720847605588 24.92625926651019 0.31343929004438636 0.21422671417549122 36.040309970226 0.029999999999994212 1.5228787452804213 4.232519345892322 RVNNGNTAPEDSS(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 2 RVNNGNTAPEDSSPAK 16 1 E9PJ27;G3V167;Q9UGN5-2;Q9UGN5 E9PJ27 PARP2 Poly [ADP-ribose] polymerase 2 1 RVNNGNTAPEDS(0.137)S(0.863)PAK;RVNNGNTAPEDS(0.073)S(0.927)PAK 94.45 0.0093461 2708700.0 21402.9 16659.2 16588.4 14351.099999999999 14180.900000000001 13250.6 14047.0 12180.9 15830.1 13039.1 True False 21097.690721188836 16620.626645938206 15224.565785075753 15406.527767866182 13346.807342722099 12683.902726657256 14774.284927501138 12746.8690825617 14047.147439656934 15292.891061491366 1.37957503498566 1.0868204435059488 0.9955322197653221 1.0074306882797956 0.8727458587820814 0.8293986189829249 0.9660884176899608 0.8335159801575558 0.9185409994208809 1.0 13.900573547909616 -1.5228787457278785 0.7015010538013432 0.8981085279652671 62.2543910519992 0.8588635236785945 0.05713239660486121 93.6926635572911 0.49444791695348045 0.021883271168324107 9018.77191797508 0.029999999969084968 1.5228787457278785 61.35628252403393 RVNS(ph)GDTEVGSSLLR ddPTM_PC-9_AZD4547_30min_R2 1 RVNSGDTEVGSSLLR 15 1 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 RVNS(0.81)GDT(0.188)EVGS(0.001)S(0.001)LLR 119.68 0.00013719 5615600.0 12577.0 15101.0 23982.0 27996.0 24495.0 18215.0 11772.0 20385.0 14197.0 14116.0 True False 16576.224382148685 19982.102933849972 23663.983010439573 21541.954733888262 21094.292064477213 17076.01317051856 12819.685194614218 17234.966650698916 14947.424436250061 13621.803136575998 1.2168891457284206 1.4669205488806316 1.737213698742955 1.5814319527233374 1.548568266108382 1.2535795004016492 0.9411151421056727 1.2652485488078438 1.097316139895946 1.0 13.733630067041489 -6.908586426828331 3.8247417760153963 1.0969062977966417 1.5239016912034538 0.6645150750396942 0.14526353979984194 0.1476201109839363 4.149945456227259 0.05619197942124383 0.04881735258705393 1.234279662747973e-07 6.908586426828331 0.42699539340681203 RVNS(ph)GDTEVGSSLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVNSGDTEVGSSLLR 15 1 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 RVNS(0.997)GDT(0.003)EVGSSLLR 97.214 0.005319 0.0 7328.7 6199.7 7914.9 9123.7 13102.0 14913.0 12297.0 13480.0 12850.0 9337.5 True False 8569.304161577009 6815.165243610095 8103.621233425404 8612.528668434501 10534.757153493963 14130.936027163903 11132.139137429733 13126.1642832406 13037.906940188384 11030.314834390665 0.7768866338120614 0.6178577262692047 0.7346681717696468 0.7808053349104856 0.9550731154697746 1.2810999721518395 1.0092313142977203 1.1900081258166293 1.182006781849815 1.0 13.429186349402759 -6.368022149741427 2.4162684702722133 1.1368163104840803 0.7092140845872996 0.8164807471977938 0.09009443386185066 0.11258580258027623 1.2865422081429747 0.029227806503308026 0.03458957406221321 4.2852666426696716e-07 6.368022149741427 -0.42760222589678065 RVNS(ph)GDTEVGSSLLR ddPTM_PC-9_Lapatinib_30min_R1 1 RVNSGDTEVGSSLLR 15 1 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 RVNS(0.616)GDT(0.384)EVGSSLLR 108.25 0.0011073 3679900.0 14911.0 10322.0 11924.0 12680.0 14136.0 17255.0 10878.0 13085.0 18153.0 14320.0 True False 14698.36640565749 10298.10004318179 10943.654747971073 13612.529499240005 13304.548272445298 16517.043873369574 11441.209613537221 13692.976869141015 16108.417980435526 16795.192919799396 0.8751531748307568 0.6131575917202856 0.6515944651680599 0.810501526492891 0.7921640636089942 0.983438770381618 0.6812193029381336 0.8152914309783686 0.959108838901502 1.0 14.035760746889611 -8.019221450139955 0.2673727968989899 1.0373763278810433 0.6824483958719189 0.3587124274233826 0.1052572358152132 2.083268571219577 0.5967978539616685 0.2780323195578581 0.2544644593381728 9.567061149972252e-09 8.019221450139955 -0.3549279320091244 RVPDHHPC ddPTM_PC-9_AZD4547_30min_R2 1 RVPDHHPC 8 1 P78371;P78371-2 P78371 CCT2 T-complex protein 1 subunit beta 0 62.717 0.038504000000000004 696030.0 2837.6 3548.7 3849.0 5397.7 5259.2 3590.8 5291.1 3826.7 2719.5 5321.0 False True 3739.897774253406 4695.747876389204 3797.959745108079 4153.343658633687 4529.050860400022 3366.2667083556444 5761.997649781115 3235.371443817981 2863.2472180307145 5134.7134095863485 0.7283556989317329 0.9145102173808553 0.7396634324356658 0.8088754575629332 0.882045500717611 0.6555899891259618 1.1221653849314446 0.6300977651016791 0.5576255166812469 1.0 12.326068040444722 -10.786730370507122 5.6428716355011925 1.0000147107609285 0.7902863128195139 0.1500291815537823 0.15449051598316382 2.8002167929292868e-05 3.6530329292409846e-06 0.14650052666997976 0.035529105977825756 1.6340661345812037e-11 10.786730370507122 -0.20972839794141462 RVPDHHPC ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVPDHHPC 8 1 P78371;P78371-2 P78371 CCT2 T-complex protein 1 subunit beta 0 62.717 0.038504000000000004 437270.0 2481.4 4533.5 3612.3 2201.3 3804.5 2234.7 2026.4 3085.5 2203.6 913.98 False True 2901.4520101160074 4983.5559191422735 3698.4309317240377 2077.9682977108914 3059.035535831767 2117.5083980354843 1834.4447221344733 3004.5088943574833 2235.823481198377 1079.677338938301 2.687332507107304 4.615782641175784 3.4254964870901925 1.9246197199565733 2.8332867844015923 1.9612418652018135 1.6990675417327656 2.7827840652022595 2.0708256073957894 1.0 10.076384512732195 -5.687764343783181 5.0338988944743095 2.1288372884637035 3.728665714988438 0.5293510107327773 0.660032852839687 0.1494170507333244 6.881346776741169 0.17178846441178058 0.30039259182766753 2.052275479375137e-06 5.687764343783181 1.5998284265247347 RVPDHHPC ddPTM_PC-9_Lapatinib_30min_R1 1 RVPDHHPC 8 1 P78371;P78371-2 P78371 CCT2 T-complex protein 1 subunit beta 0 69.998 0.024891999999999997 588680.0 827.03 2502.8 3022.4 2071.7 2471.9 3169.1 2198.1 2939.7 3607.6 2103.6 False True 815.2364005412727 2497.0049203715735 2773.9099388013897 2224.059728988606 2326.5077019423857 3033.564980532919 2311.906862614097 3076.2891939024717 3201.2740982878413 2467.2044571291904 0.3304292022436892 1.01207863545977 1.1243129570335968 0.9014492992512243 0.9429732080856738 1.2295555691654103 0.9370552391528201 1.2468724207324127 1.2975309318356232 1.0 11.268661561331324 -4.761078751217617 4.308060364750778 1.0815755484602168 0.2596801367909791 0.740958217175709 0.13301023005343973 0.11516114828524003 4.412284592372048 0.034499554485884716 0.2987173677373496 1.7334896331859667e-05 4.761078751217617 -0.8218954116692376 down RVPDPS(ph)PVTK ddPTM_PC-9_Lapatinib_30min_R1 1 RVPDPSPVTK 10 1 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 RVPDPS(0.999)PVT(0.001)K 53.869 0.044522000000000006 12515000.0 88537.0 97635.0 103020.0 74911.0 79645.0 79631.0 76019.0 69607.0 77808.0 54998.0 True False 87274.4461443027 97408.9321561763 94550.09326870031 80420.20483577048 74960.4376880947 76225.36775892744 79954.89185617628 72841.19533284666 69044.44368543643 64504.33101977149 1.3530013375001415 1.5101146018601308 1.4657944943219297 1.246741165505934 1.1620992963266026 1.1817092984897912 1.2395274951641462 1.1292450317873974 1.0703846174960459 1.0 15.977108410333019 -6.042977027432592 0.3514263386387207 1.0187467423164698 1.5965577830016588 0.7896462932765492 0.07174377122840053 1.321183560863718 0.24827925873649928 0.0844425343494042 0.3017188177586502 9.057805120608128e-07 6.042977027432592 0.5778110406851891 RVPGS(ph)SGHLHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVPGSSGHLHK 11 1 Q9UEW8-2;Q9UEW8 Q9UEW8-2 STK39 STE20/SPS1-related proline-alanine-rich protein kinase 1 RVPGS(0.5)S(0.5)GHLHK 58.098 0.026965 17056000.0 29811.0 27896.0 54328.0 64586.0 79419.0 68616.0 61547.0 55303.0 58714.0 48156.0 True False 34857.41350591132 30665.33052175864 55623.38556008734 60967.455810637184 63857.417064061716 65017.656168435446 55716.82259830755 53851.35484837203 59572.58117402496 56886.301597313715 0.6127558397566375 0.5390635295441094 0.9777992943509266 1.0717423017269274 1.1225447123649395 1.142940467965063 0.9794418169898852 0.9466489002848973 1.0472219058241272 1.0 15.795793668339948 -5.316738384068629 4.472134079902091 1.0446669920333662 0.5727630156485732 0.9025234141231595 0.060674217538582376 0.05874614979789093 2.4816243259229624 0.017935863811086746 0.041022312193890284 4.8223820703914005e-06 5.316738384068629 -0.471903976384793 RVPGS(ph)SGHLHK ddPTM_PC-9_Lapatinib_30min_R1 1 RVPGSSGHLHK 11 1 Q9UEW8-2;Q9UEW8 Q9UEW8-2 STK39 STE20/SPS1-related proline-alanine-rich protein kinase 1 RVPGS(0.716)S(0.284)GHLHK 48.532 0.044467 6826400.0 16746.0 13303.0 22993.0 13113.0 17841.0 18558.0 14579.0 16935.0 24034.0 13274.0 True False 16507.198969159705 13272.19772083388 21102.604295546706 14077.37376368566 16791.62745675556 17764.317600810944 15333.829284405136 17721.861924257013 21327.037830760048 15568.393213506788 1.0603020326361252 0.8525091535662922 1.355477344780742 0.9042277883547062 1.078571643616216 1.141050162157969 0.9849333244680543 1.138323119233777 1.3698933177161268 1.0 13.926332433630813 -7.997155748748985 24.235897984276612 1.2080004985686985 1.0566537933588214 0.10711697812755772 0.1537654066040969 102.22399583996491 871055.1670594218 0.07986915167721566 0.037992915784892674 1.0065706229800083e-08 7.997155748748985 -0.15134670520987714 RVPGS(ph)SGR ddPTM_PC-9_AZD4547_30min_R2 1 RVPGSSGR 8 1 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 RVPGS(0.5)S(0.5)GR 58.63 0.035256 19069000.0 6307.2 5192.2 5771.3 11279.0 8071.4 8567.2 9476.6 11830.0 21366.0 19375.0 True False 8312.75840209018 6870.477110995021 5694.768791099569 8678.800808812892 6950.825432505468 8031.491629671516 10319.999041393228 10001.945326356052 22495.3631404465 18696.687147291035 0.44461130127508264 0.3674702933664098 0.30458705043501166 0.4641892299123358 0.37176775638097864 0.42956763229763945 0.5519693922293872 0.5349581584994983 1.2031737474788873 1.0 14.19049504219809 -8.166022228421179 3.905190461070826 1.1024288802237496 0.4198733049380835 0.9175354608329994 0.08044161254863569 0.060356032222986106 1.5978962789138855 0.06591984928415737 0.02199650457341801 6.8230377100917405e-09 8.166022228421179 -0.6825555752856661 down RVPGS(ph)SGR ddPTM_PC-9_Lapatinib_30min_R1 1 RVPGSSGR 8 1 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 RVPGS(0.772)S(0.228)GR 54.486000000000004 0.042717000000000005 19749000.0 5988.9 6362.5 5383.2 4562.3 7066.4 3991.9 5538.8 4451.2 5961.5 7007.8 True False 5903.497187770246 6347.768022160838 4940.614075752924 4897.826761386646 6650.768245076928 3821.1757425734017 5825.57196244346 4658.01900190451 5290.053092621953 8219.088892693453 0.7182666187025054 0.772320156775994 0.60111456881127 0.595908722406042 0.809185583938541 0.4649147603173295 0.7087856134056701 0.5667317950588614 0.6436301105496822 1.0 13.004762760947965 -11.090335099370796 10.26558612300744 1.000012632881686 0.6518098526650771 0.5325051128638703 0.09740764910156477 2.7306618324467896e-05 1.1504961711613354e-06 0.09144590487281139 0.022178086939631792 8.12203582252232e-12 11.090335099370796 -0.348202780216609 RVPGSS(ph)GHLHK ddPTM_PC-9_AZD4547_30min_R2 2 RVPGSSGHLHK 11 1 Q9UEW8-2;Q9UEW8 Q9UEW8-2 STK39 STE20/SPS1-related proline-alanine-rich protein kinase 1 RVPGS(0.195)S(0.805)GHLHK;RVPGS(0.151)S(0.849)GHLHK 69.345 0.012818000000000001 43937000.0 78477.0 86557.0 211616.0 363972.0 300010.0 293875.0 195366.0 356473.0 237448.0 267792.0 True False 103431.05357699636 114534.85753561025 208809.83357256197 280063.87871134386 258358.79004955362 275498.94979336445 212753.19552590858 301388.2887846249 249999.01652030056 258416.68358954164 0.40024913306790194 0.44321773634992034 0.8080354204383602 1.0837685664141783 0.9997759682572198 1.0661035733705009 0.8232951238699315 1.1662880453312279 0.9674259921909246 1.0 17.979339689031 -5.379534505758042 2.5964569640038353 1.0152212568067789 0.3996982862183545 0.883444085642801 0.08525954789086528 0.08229331392137561 1.0581146626040279 0.022715322619663865 0.061081941997968195 4.173164403369435e-06 5.379534505758042 -0.6155229705884244 down RVPGSS(ph)GHLHK ddPTM_PC-9_Lapatinib_30min_R1 1 RVPGSSGHLHK 11 1 Q9UEW8-2;Q9UEW8 Q9UEW8-2 STK39 STE20/SPS1-related proline-alanine-rich protein kinase 1 RVPGS(0.242)S(0.758)GHLHK 54.199 0.033044 17213000.0 34505.0 22691.0 43340.0 30709.0 34242.0 33668.0 26799.0 27324.0 40989.0 26741.0 True False 34012.95237255795 22638.460383630892 39776.75249723802 32967.442302220916 32227.95288236221 32228.098123941283 28186.521091485916 28593.572791166152 36372.38718669483 31363.146219857255 1.0844878933422502 0.7218172636423058 1.268264102663711 1.0511522686887809 1.0275739766808667 1.0275786076441653 0.8987147173914557 0.9116933802088524 1.1597174254050453 1.0 14.93678267140402 -10.908036062956159 15.744228842822965 0.9999996543589819 1.010582146694306 0.0 0.14212859863718308 0.0 0.0 0.13393217965312795 0.032483324904649835 1.2358448070713167e-11 10.908036062956159 0.010582492335324045 RVPGSS(ph)GR ddPTM_PC-9_AZD4547_30min_R2 1 RVPGSSGR 8 1 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 RVPGS(0.234)S(0.766)GR 66.92 0.021884 26245000.0 8817.2 5371.7 8456.3 9479.2 12165.0 11445.0 12450.0 15132.0 22463.0 24367.0 True False 11620.88619084689 7107.996975681201 8344.163936751731 7293.916892180087 10476.099733184947 10729.342340740319 13558.025881154172 12793.697098767518 23650.348320876612 23513.918746737574 0.4942130793260151 0.3022889145888282 0.3548606264495763 0.31019571730008116 0.4455275977611536 0.45629750005957453 0.5765957613098953 0.544090384787205 1.0058020772976417 1.0 14.521227373043052 -8.068427270566527 1.0719796506707837 1.04000327675212 0.37977676611235084 0.882165594522716 0.08343234866327616 0.1491860876100631 0.32192439776946324 0.07511376576851544 0.026486622228334485 8.542258889853638e-09 8.068427270566527 -0.6602265106397691 down RVPGSS(ph)GR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVPGSSGR 8 1 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 RVPGS(0.233)S(0.767)GR 72.096 0.01541 27484000.0 4442.3 2094.9 8422.3 6888.0 17025.0 15785.0 9063.6 9825.0 13776.0 13041.0 True False 5194.293650575619 2302.8678272882194 8623.11957375062 6502.087691197299 13689.073464985095 14957.206812095637 8205.030193218514 9567.104160447994 13977.447938368497 15405.230067500805 0.337177285104856 0.1494861042125166 0.5597527291683968 0.4220701451849291 0.8885990929706302 0.9709174576788485 0.5326132850510307 0.6210296190662519 0.907318350788906 1.0 13.91113260783804 -5.842622584475667 1.513960553049086 0.7900428792870595 0.2645140511156034 0.6220114459521014 0.17065595481925294 0.2826320562602151 1.3166873588878256 0.05831565223033346 0.12024279282223253 1.4367374608974584e-06 5.842622584475667 -0.5255288281714561 RVPGSS(ph)GR ddPTM_PC-9_Lapatinib_30min_R1 1 RVPGSSGR 8 1 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 RVPGS(0.238)S(0.762)GR 63.693999999999996 0.026136000000000003 37453000.0 11105.0 11090.0 8073.4 9496.0 9933.2 6635.0 9347.1 8301.6 11706.0 15282.0 True False 10946.640663592412 11064.321786367573 7409.636216225228 10194.367517727369 9348.948705422586 6351.236516940436 9831.047102288447 8687.322642480784 10387.547010355214 17923.473338014974 0.6107432670639247 0.6173090213993616 0.4134040359526568 0.5687718739261056 0.5216036272162627 0.3543529982812938 0.5485012261232418 0.4846896847864481 0.5795498904960369 1.0 14.129562619733344 -8.767414744773511 3.254214828670615 0.9999897719465799 0.5131145621159946 0.77461696454117 0.07800844747676504 0.9602450916738475 12.295177054938248 0.07657181562215196 0.020250293918203446 1.7083830554032918e-09 8.767414744773511 -0.4868752098305853 RVPLS(ph)PLSLLAGPADAR ddPTM_PC-9_Lapatinib_30min_R1 1 RVPLSPLSLLAGPADAR 17 1 Q53ET0;H0YDQ8;Q5T4K5 Q53ET0 CRTC2 CREB-regulated transcription coactivator 2 1 RVPLS(0.995)PLS(0.005)LLAGPADAR 61.16 0.015174000000000002 7512300.0 6162.0 5884.6 7371.7 5761.1 6745.0 6372.7 5707.4 6098.2 11264.0 5951.8 True False 6074.128750027595 5870.974570248745 6765.627281584899 6184.790512466213 6348.272361180219 6100.154476489266 6002.901245477326 6381.544634573615 9995.329704821548 6980.560699725008 0.8701491200079213 0.8410462744747749 0.9692097200517752 0.8860019672502606 0.9094215542643019 0.8738774346206281 0.8599454261193952 0.9141879727261751 1.4318806374988335 1.0 12.769127207375586 -8.146593156215014 7.8669992340642265 1.2139727596168561 0.8888868899390644 0.6202734372371995 0.10199204601433887 0.1510304465613242 9.173474135111546 0.06258243989401084 0.02346498675022183 7.135211383425444e-09 8.146593156215014 -0.32508586967779174 RVPPPALS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 RVPPPALSR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 RVPPPALS(1)R;RVPPPALS(1)R 71.888 0.01548 22753200.0 32228.0 36561.0 52049.0 54461.0 36796.0 53966.0 39501.0 66366.0 52452.0 40399.0 True False 42475.8336159567 48378.62826067737 51358.79625178753 41905.85786406232 31687.510545193065 50591.49748889404 43016.512476423384 56110.65963896419 55224.50563711968 38984.643306498605 1.0895529627399752 1.2409662922993274 1.3174109571300399 1.0749324428749296 0.8128203276368279 1.2977288798346043 1.103421984349737 1.4393016039115776 1.4165707558984884 1.0 15.25061831407303 -7.7440786046810635 24.988759929674725 1.3209521644064708 1.1367061453603842 0.12586488509749494 0.1754029219166732 399.65860741359444 575262.4925555254 0.08383837151726237 0.048255333596922655 1.80269143505692e-08 7.7440786046810635 -0.18424601904608662 RVPPPALS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RVPPPALSR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 RVPPPALS(1)R;RVPPPALS(1)R 77.67399999999999 0.010413 19673800.0 45962.0 59905.0 68153.0 63430.0 69280.0 55104.0 57037.0 50165.0 57400.0 44131.0 True False 53742.45880912067 65851.97250164728 69778.0259916919 59876.22274283463 55705.081330641304 52214.249234952025 51634.042447879954 48848.221904211045 58239.366409868766 52131.60095919622 1.0308998346547094 1.2631872279002154 1.3384976618367748 1.1485590628551803 1.0685472977175987 1.0015853776641253 0.9904557216321496 0.9370174904554514 1.1171605194985885 1.0 15.6698705452656 -6.285255228292175 2.4602332393982373 1.0063606263565799 1.2174919515191625 0.522515533782784 0.08437392283058895 0.2248821705727837 2.684060216682639 0.028363244751921084 0.035421712990035874 5.184952375726066e-07 6.285255228292175 0.2111313251625826 RVPPPALS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 RVPPPALSR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 RVPPPALS(1)R 81.709 0.007718399999999999 18566000.0 14585.0 17683.0 17483.0 13968.0 14101.0 17514.0 14509.0 12179.0 13407.0 11452.0 True False 14377.01522543858 17642.056099940284 16045.615226331622 14995.25331588206 13271.60690363266 16764.967047128077 15260.20502691777 12744.880801625408 11896.962478031128 13431.462941169188 1.0703983094329323 1.3134873079137999 1.1946290062826825 1.1164274049343985 0.9880983897110308 1.2481862266649497 1.1361536039490716 0.948882549685685 0.8857532891346768 1.0 13.713328829737346 -7.7542445550425745 4.928757500254367 0.934629411592308 1.1575512316635956 0.5354505937140799 0.08866912418984307 0.14053838963303616 9.16476057478385 0.04826019407065173 0.024778139410278503 1.7609841415039245e-08 7.7542445550425745 0.2229218200712877 RVPS(ph)PTPAPK ddPTM_PC-9_AZD4547_30min_R2 6 RVPSPTPAPK 10 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 RVPS(0.987)PT(0.013)PAPK;RVPS(0.978)PT(0.022)PAPK;RVPS(0.833)PT(0.167)PAPK;RVPS(0.993)PT(0.007)PAPK;RVPS(0.988)PT(0.012)PAPK;RVPS(0.915)PT(0.085)PAPK 135.1 0.00016566 4153597000.0 880019.0 750782.0 1075665.0 1357121.0 1240995.0 1086256.0 962368.0 1163998.0 957866.0 1077255.0 True False 1159846.736467688 993457.5991577873 1061400.9792729733 1044257.7207604374 1068704.2653829698 1018332.2406014173 1048016.8876461501 984128.8551130824 1008496.8412378042 1039540.6303409046 1.115730066353761 0.9556698123785649 1.0210288547595296 1.0045376681602007 1.028054348421669 0.979598306097442 1.0081538489769908 0.946695902391376 0.970137012256154 1.0 19.9875147162129 -4.7511045966830725 24.998682957792106 0.9915530064053144 1.115730323025195 0.6808528623122515 0.025725557572926182 267.1728184870495 646218.3431840956 0.006599030424870371 0.09027415587115012 1.773762231645123e-05 4.7511045966830725 0.12417731661988052 RVPS(ph)PTPAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 RVPSPTPAPK 10 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 RVPS(0.99)PT(0.01)PAPK;RVPS(0.915)PT(0.085)PAPK;RVPS(0.986)PT(0.014)PAPK;RVPS(0.821)PT(0.179)PAPK;RVPS(0.993)PT(0.007)PAPK;RVPS(0.988)PT(0.012)PAPK;RVPS(0.5)PT(0.5)PAPK;RVPS(0.727)PT(0.273)PAPK 129.74 0.00034701 1162850000.0 496302.0 504403.0 521355.0 627067.0 663545.0 581513.0 598286.0 523584.0 518907.0 436002.0 True False 580316.1261886816 554476.796356705 533786.0804498477 591934.4689686443 533528.1205476391 551017.4345848704 541612.0188644615 509840.474783104 526495.0331994024 515045.7112100674 1.1267274215821843 1.076558418579968 1.036385836891547 1.149285308245615 1.035884988332683 1.0698418074199467 1.0515804851417523 0.9898936418386359 1.0222297200814188 1.0 18.974340954129794 -7.332554522431047 0.9342391726773736 0.999389020456325 1.0895741291929226 0.5235124849029206 0.03365700543081515 0.47406427786178984 0.791644206093717 0.02579171339133682 0.01405638377410316 4.649919962272266e-08 7.332554522431047 0.09018510873659757 RVPS(ph)PTPAPK ddPTM_PC-9_Lapatinib_30min_R1 5 RVPSPTPAPK 10 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 RVPS(0.947)PT(0.053)PAPK;RVPS(0.978)PT(0.022)PAPK;RVPS(0.979)PT(0.021)PAPK;RVPS(0.996)PT(0.004)PAPK;RVPS(0.996)PT(0.004)PAPK 129.74 0.00034701 1765834000.0 811946.0 656099.0 729033.0 633340.0 681964.0 681827.0 594245.0 593838.0 695109.0 554757.0 True False 800367.5011473402 654579.843076104 669094.7208887612 679917.9363603045 641852.2183128098 652666.8486263668 625012.0984368838 621429.8813922013 616818.5045977272 650646.0082827621 1.230112059335821 1.0060460446129906 1.0283544544516463 1.0449890227633905 0.9864845248291593 1.0031058983193308 0.9606023713055069 0.955096739980515 0.9480093580004967 1.0 19.311513315836066 -1.9205112225843264 1.1224090550948063 0.9847649445295921 199.99999980040624 0.8418539170647452 0.030708589834502264 526.669133493196 1.0837850646768208 0.010149325819820426 269336.15475519106 0.01200850041501397 1.9205112225843264 199.01523485587666 RVPSPTPAPK ddPTM_PC-9_AZD4547_30min_R2 1 RVPSPTPAPK 10 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 74.84100000000001 0.016025 4632300.0 11098.0 8623.0 16894.0 22164.0 14751.0 14388.0 13350.0 14212.0 11561.0 13679.0 False True 14626.933147259759 11410.216118044387 16669.9745216565 17054.43223038648 12703.078270794174 13488.316085502116 14538.12413762315 12015.861959270687 12172.09085775072 13200.10237356355 1.108092402113016 0.8644036080277794 1.2628670634435548 1.2919924215544094 0.9623469509020787 1.0218342027798046 1.101364499016259 0.9102855128862792 0.9221209437078551 1.0 13.688261498016491 -7.37258416092512 1.1165568854309686 0.9424447885508438 1.103257822288099 0.19599135701424142 0.12388339227108039 0.9028793970490974 2.144581558370996 0.0967028374494634 0.050138639615938826 4.240488005095056e-08 7.37258416092512 0.1608130337372553 RVPSPTPAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RVPSPTPAPK 10 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 ; 84.31 0.022681 1671300.0 32506.0 35798.0 38548.0 34886.0 41926.0 34181.0 44510.0 35643.0 29560.0 29102.0 False True 38008.623777235036 39351.78885925998 39467.13051410408 32931.450521938 33710.90126830925 32388.48818778847 40293.69057550603 34707.40901688016 29992.259077974206 34377.96222869475 1.1056101442077282 1.1446806706423587 1.1480357751152999 0.9579232853554838 0.9805962623395778 0.9421293784759093 1.1720790868131652 1.0095830807537054 0.8724269018173548 1.0 15.06919641041294 -5.755271161197442 24.992142951434182 0.9961917386907787 1.1339660788235135 0.44697527861544195 0.07224623805236936 146.9790669976331 595516.5960142688 0.020624346343718573 0.034598089029679466 1.7568263587320499e-06 5.755271161197442 0.13777434013273482 RVPSPTPAPK ddPTM_PC-9_Lapatinib_30min_R1 1 RVPSPTPAPK 10 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 101.3 0.0023141 4600400.0 20790.0 15688.0 17729.0 17749.0 16778.0 14485.0 16418.0 17190.0 17002.0 16329.0 False True 20493.53078758093 15651.675399867856 16271.390055919079 19054.3206689283 15791.151026817153 13865.510316184196 17268.043706109034 17988.710155180288 15087.05572100284 19151.44589297517 1.0700774710225949 0.8172581583309568 0.8496167937840918 0.9949285696448383 0.8245409310118675 0.7239928720614313 0.9016574415638782 0.9392873131202392 0.7877763279761991 1.0 14.225165696184243 -4.752679174531512 24.935924443522236 0.867224972771619 1.0700778698183244 0.3311684141354685 0.08471846662663265 388.49692546327316 1105771.7253445482 0.020953529172582405 0.24307038012722107 1.767342924168364e-05 4.752679174531512 0.2028528970467054 RVQS(ph)LPSVPLSCAAYR ddPTM_PC-9_AZD4547_30min_R2 1 RVQSLPSVPLSCAAYR 16 1 Q96AD5-2;Q96AD5 Q96AD5-2 PNPLA2 Patatin-like phospholipase domain-containing protein 2 1 RVQS(0.969)LPS(0.031)VPLSCAAYR 56.303999999999995 0.02847 7848100.0 5256.0 11138.0 12825.0 26980.0 20812.0 20739.0 10390.0 19246.0 10926.0 19411.0 True False 6927.298668408481 14738.140684538828 12654.932120293863 20760.177836844752 17922.613041269644 19442.187051517125 11314.68987190296 16271.972929082724 11503.526054128906 18731.42679824856 0.3698222641030315 0.7868135643525502 0.6755989416394662 1.1083073414773659 0.9568204939383185 1.0379448005175462 0.6040484792627177 0.8686990641099586 0.6141297285054931 1.0 14.193173175358847 -4.581718374023616 1.6283404759669626 0.8656358344596219 1.1601070941241634e-11 0.4310466250958883 0.16774793647732367 1.7725790927420593 3.0729846500909406 0.047380296587857265 2.8319008668075796 2.619881366134599e-05 4.581718374023616 -0.8656358344480208 RVQS(ph)LPSVPLSCAAYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVQSLPSVPLSCAAYR 16 1 Q96AD5-2;Q96AD5 Q96AD5-2 PNPLA2 Patatin-like phospholipase domain-containing protein 2 1 RVQS(0.999)LPS(0.001)VPLSCAAYR 62.468 0.017109 5294100.0 9463.4 9430.2 9421.8 10135.0 17715.0 16871.0 10971.0 13586.0 13450.0 7476.4 True False 11065.366709330156 10366.367933979362 9646.451444375482 9567.168808113336 14243.872918191551 15986.255060301894 9931.747456838384 13229.381895556886 13646.680805099904 8831.81213685016 1.2528987865537398 1.173753219990535 1.092239202431208 1.0832622637199163 1.6127916556059794 1.8100764387412962 1.1245424271876001 1.4979238338141447 1.5451733566840737 1.0 13.108493769264902 -6.251294327756548 24.752513536421034 1.460203293556567 1.1480323312503213 0.2708648248653218 0.2231051501419411 766.9380267899412 1871220.9776608427 0.065526842425233 0.08360434218206174 5.606678743838682e-07 6.251294327756548 -0.31217096230624564 RVQT(ph)PLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVQTPLLR 8 1 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 SEPT9 Septin-9 1 RVQT(1)PLLR 70.72800000000001 0.031704 23492000.0 16044.0 15392.0 20971.0 21674.0 22610.0 20268.0 19405.0 19991.0 17343.0 12972.0 True False 18759.932316555678 16920.016037815785 21471.028172960378 20459.67604805609 18179.73280724306 19205.11040022517 17566.817919966164 19466.257432215345 17596.60856526749 15323.720913704494 1.2242413198597262 1.1041715085455304 1.4011628307429007 1.335163708819465 1.18637848533148 1.2532928854798853 1.1463807008032623 1.2703348972380493 1.1483247877172102 1.0 13.903479035294604 -9.138675091464425 0.5709371165631792 0.9890841589739761 1.2519958977775063 0.44618267871002937 0.08204397745838647 2.175238616905979 1.1399322645270895 0.13590810574057618 0.03804840746198654 7.266493820094256e-10 9.138675091464425 0.26291173880353025 RVQT(ph)PLLR ddPTM_PC-9_Lapatinib_30min_R1 1 RVQTPLLR 8 1 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 SEPT9 Septin-9 1 RVQT(1)PLLR 65.695 0.043364 36122000.0 50084.0 44744.0 51363.0 29859.0 36900.0 32858.0 28861.0 28190.0 42571.0 34431.0 True False 49369.79297571924 44640.398017063155 47140.13240691364 32054.93046670406 34729.614548191275 31452.739935739082 30355.28136204245 29499.810312654594 37776.2056874963 40382.35247357636 1.2225586166141185 1.1054432266241296 1.1673448801121515 0.7937856143393025 0.8600195981875035 0.7788733941718664 0.7516967066716833 0.7305124269805082 0.9354632252347024 1.0 15.301437336853423 -5.7596265662449815 24.992133849658227 0.8196731039896145 1.1591484207044747 0.7648836852919778 0.08332495624729416 20.410753363780497 281380.89826808 0.022150822126336848 0.035985233087654486 1.7392957419972739e-06 5.7596265662449815 0.3394753167148602 RVS(ph)ADSQPFQHGDK ddPTM_PC-9_AZD4547_30min_R2 1 RVSADSQPFQHGDK 14 1 D6RED3;D6RAZ0;F2Z2L2;H0YAM8;E9PD12;Q96AX9-8;Q96AX9-7;Q96AX9-10;Q96AX9-4;Q96AX9-9;Q96AX9-6;Q96AX9-5;Q96AX9-2;Q96AX9-12;Q96AX9-3;Q96AX9;Q96AX9-11;Q96AX9-13;Q96AX9-14 D6RED3 MIB2 E3 ubiquitin-protein ligase MIB2 1 RVS(0.629)ADS(0.371)QPFQHGDK 80.459 0.0053051 7303800.0 19960.0 21576.0 27956.0 40927.0 33696.0 28881.0 29845.0 31766.0 33535.0 26572.0 True False 26306.864806208778 28550.020058323746 27585.285173874094 31491.912465846755 29017.892035297995 27075.066504405542 32501.147182573994 26857.294610061406 35307.5916369406 25641.72236788734 1.0259398502479082 1.1134205280250065 1.0757968898540446 1.2281512144163123 1.1316670393264545 1.0558989024198024 1.2675102988899498 1.0474060293116814 1.3769586586413711 1.0 14.64620555134048 -3.182739403347496 0.6641363910436408 1.1600847929275737 0.013825219811353918 0.11084476469281568 0.10863853553463558 48.360008445728994 2.952996523621547 0.04200256021572657 66.76752980422123 0.0006565391017718151 3.182739403347496 -1.1462595731162197 RVS(ph)ADSQPFQHGDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RVSADSQPFQHGDK 14 1 D6RED3;D6RAZ0;F2Z2L2;H0YAM8;E9PD12;Q96AX9-8;Q96AX9-7;Q96AX9-10;Q96AX9-4;Q96AX9-9;Q96AX9-6;Q96AX9-5;Q96AX9-2;Q96AX9-12;Q96AX9-3;Q96AX9;Q96AX9-11;Q96AX9-13;Q96AX9-14 D6RED3 MIB2 E3 ubiquitin-protein ligase MIB2 1 RVS(0.985)ADS(0.015)QPFQHGDK;RVS(0.958)ADS(0.042)QPFQHGDK 101.92 0.00072848 11662300.0 33061.0 40805.0 53644.0 49239.0 58508.0 46730.0 49851.0 48192.0 42886.0 33605.0 True False 38657.57431548537 44855.85072914974 54923.07640600292 46480.29846499185 47043.777403192245 44279.39653653655 45128.75239001458 46927.01106364474 43513.1266176591 39697.32048296635 0.9738081524185713 1.1299465602066732 1.3835461874453152 1.1708674011117701 1.1850617832853019 1.1154253233675133 1.1368211214502197 1.1821203671361287 1.096122511249344 1.0 15.276754010182186 -8.87654190650033 0.8605841374188343 0.998480766477997 1.1693800220209416 0.20297244370197376 0.09526390938461954 2.019083107297433 2.6930240396284093 0.09839874345295535 0.03313471452667952 1.3287953311163994e-09 8.87654190650033 0.1708992555429446 RVS(ph)EVEAVLSQK ddPTM_PC-9_AZD4547_30min_R2 3 RVSEVEAVLSQK 12 1 H7BYJ3;O14578;O14578-4;O14578-3 H7BYJ3 CIT Citron Rho-interacting kinase 1 RVS(1)EVEAVLSQK;RVS(1)EVEAVLSQK;RVS(1)EVEAVLSQK 133.23 9.3795e-05 22225300.0 132659.0 116888.0 145506.0 182521.0 162344.0 145386.0 137199.0 164583.0 145728.0 150182.0 True False 174841.80252138493 154669.76013057792 143576.49536806846 140443.6033713394 139805.33786142027 136294.990436948 149409.44521031895 139150.47909109548 153430.88457039138 144924.173891843 1.2064364268991417 1.067246105166748 0.990700802443212 0.969083346137633 0.9646792119426333 0.9404572527607783 1.0309490901209022 0.9601605815945072 1.0586976654764093 1.0 17.144938736309108 -4.801632847075841 1.936882455725261 0.9854851974590455 1.2685092742293254 0.799759201087894 0.03331082596634307 0.30457141938801857 1.2736214710118978 0.008856136084766297 0.154757410979383 1.578945547528087e-05 4.801632847075841 0.28302407677027985 RVS(ph)EVEAVLSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RVSEVEAVLSQK 12 1 H7BYJ3;O14578;O14578-4;O14578-3 H7BYJ3 CIT Citron Rho-interacting kinase 1 RVS(1)EVEAVLSQK;RVS(1)EVEAVLSQK;RVS(1)EVEAVLSQK;RVS(1)EVEAVLSQK;RVS(1)EVEAVLSQK 109.1 0.00062005 23984600.0 150017.0 142998.0 158749.0 166537.0 173227.0 152743.0 161105.0 157417.0 140551.0 131055.0 True False 175411.91512919072 157193.89639914106 162534.17821893512 157206.4718102389 139284.4128704242 144732.8881913162 145843.9681008063 153284.97054709852 142606.29247863207 154814.2340691905 1.1330477212501957 1.0153710822797277 1.0498658550110733 1.015452311316408 0.8996873815115369 0.9348810144074433 0.9420578732807271 0.9901219449795002 0.9211445790888815 1.0 17.24017859757909 -6.006481828934666 3.5128251774662376 0.9465844743466404 1.0600650840257089 0.6470183312924321 0.03926238914608121 0.14834600046380741 3.9087536788894663 0.011511494614644492 0.016665966481565847 9.851858625360707e-07 6.006481828934666 0.11348060967906848 RVS(ph)EVEAVLSQK ddPTM_PC-9_Lapatinib_30min_R1 3 RVSEVEAVLSQK 12 1 H7BYJ3;O14578;O14578-4;O14578-3 H7BYJ3 CIT Citron Rho-interacting kinase 1 RVS(1)EVEAVLSQK;RVS(1)EVEAVLSQK;RVS(1)EVEAVLSQK 127.57 0.00015314 12186000.0 92672.0 78222.0 84846.0 78805.0 85640.0 75305.0 59179.0 61723.0 83349.0 67525.0 True False 91350.48028603637 78040.88176494518 77870.28939503129 84600.58258577366 80602.82357471823 72084.38069452891 62242.99905492912 64590.875910889656 73961.35791611957 79196.60627859332 1.153464581104509 0.9854068934521942 0.9832528570871284 1.0682349479492914 1.0177560297366557 0.9101953237864079 0.7859301298337739 0.8155763099706008 0.9338955466846964 1.0 16.273150989021687 -6.805182833443428 3.4836105051625927 0.8663677581576268 1.0387920772668486 0.5266048081894015 0.07193108227982098 0.17700355483118652 4.421545594461061 0.02592445788561527 0.023528438162945295 1.5660916230823137e-07 6.805182833443428 0.17242431910922185 RVS(ph)EVEEEKEPVPQPLPSDDTR ddPTM_PC-9_AZD4547_30min_R2 3 RVSEVEEEKEPVPQPLPSDDTR 22 2 O43290 O43290 SART1 U4/U6.U5 tri-snRNP-associated protein 1 1 RVS(1)EVEEEKEPVPQPLPSDDTR;RVS(0.999)EVEEEKEPVPQPLPS(0.001)DDTR;RVS(1)EVEEEKEPVPQPLPSDDTR 89.803 0.00058058 140031000.0 51099.0 54968.0 54595.0 51455.0 58721.0 67909.0 77463.0 74441.0 67945.0 52653.0 True False 67347.41907477254 72735.33104217374 53871.03462826069 39592.844721825284 50568.602748241145 63662.639494743045 84357.05693428488 62937.85393400422 71536.43398753332 50809.63449632592 1.3254852104799628 1.4315263584002613 1.0602523549378444 0.779238920222665 0.9952561802407336 1.2529639334316907 1.6602571101034942 1.2386992065167346 1.4079304977623126 1.0 15.632814465565913 -6.9956638476917705 23.46593120876018 1.362327176747959 1.114725648170016 0.15363379410805011 0.2262699023932739 98.99346585079968 535711.7344612292 0.08517017592660406 0.07475165058975877 1.0100343696856165e-07 6.9956638476917705 -0.24760152857794293 RVS(ph)EVEEEKEPVPQPLPSDDTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RVSEVEEEKEPVPQPLPSDDTR 22 2 O43290 O43290 SART1 U4/U6.U5 tri-snRNP-associated protein 1 1 RVS(1)EVEEEKEPVPQPLPSDDTR;RVS(1)EVEEEKEPVPQPLPSDDTR 64.035 0.0093787 20189600.0 18500.2 22705.0 22146.1 24939.0 30285.0 31046.0 43812.0 27204.0 30745.0 29497.0 True False 21631.918464394363 24959.002347882502 22674.147013551945 23541.74868332892 24350.871652691563 29417.893106640542 39661.810188588395 26489.92382502058 31194.58746117449 34844.57260187647 0.6208117032042295 0.7162952644894373 0.6507224890550354 0.6756216800908942 0.6988425982696717 0.8442604087230593 1.1382492947108929 0.7602309871234877 0.8952495362073858 1.0 15.088646338652227 -6.842754894830625 3.551100114766895 0.9351932199439063 0.6717547184649296 0.6682434133567532 0.09181957259561395 0.14903551489336578 3.704013347052256 0.03361222892617836 0.02992529847409419 1.4362998170924404e-07 6.842754894830625 -0.2634385014789766 RVS(ph)EVEEEKEPVPQPLPSDDTR ddPTM_PC-9_Lapatinib_30min_R1 4 RVSEVEEEKEPVPQPLPSDDTR 22 2 O43290 O43290 SART1 U4/U6.U5 tri-snRNP-associated protein 1 1 RVS(0.996)EVEEEKEPVPQPLPS(0.004)DDTR;RVS(1)EVEEEKEPVPQPLPSDDTR;RVS(0.998)EVEEEKEPVPQPLPS(0.002)DDTR;RVS(0.856)EVEEEKEPVPQPLPS(0.143)DDTR 77.668 0.00022667 130966500.0 56338.2 66681.0 60339.4 71862.0 107194.0 131116.0 145625.0 145290.0 132447.0 129560.0 True False 55534.80693683948 66526.60424136854 55378.52744881968 77146.97120460469 100889.05967151266 125508.47432632423 153164.74995140266 152040.70380722202 117529.42413125878 151954.27337215163 0.3654705175735929 0.4378067346512727 0.3644420536511795 0.5076985957194098 0.663943549810047 0.8259621236116281 1.007966058159394 1.0005687923949247 0.7734525757193886 1.0 17.213277722420543 -6.515120202181358 1.401133418824064 0.9474781251611891 0.3919512720758943 0.9218640062682999 0.07003299788408629 0.10389977189860038 0.41960138605247327 0.029331451745207036 0.03283153927829325 3.054075702130378e-07 6.515120202181358 -0.5555268530852948 down RVS(ph)FADPIYQAGLADDIDRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVSFADPIYQAGLADDIDRR 20 2 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 RVS(0.989)FADPIY(0.011)QAGLADDIDRR 59.07 0.045159 2264200.0 5914.8 5767.8 6962.8 5948.0 9424.5 9739.8 10113.0 11882.0 9436.6 7148.0 True False 6916.058817374936 6340.38906593775 7128.819558566046 5614.752843676184 7577.83687933933 9229.02774206202 9155.023428220447 11570.110090019642 9574.592422706744 8443.875816463134 0.8190621188306211 0.7508861100936387 0.84425916646795 0.6649497180819532 0.897435851030012 1.0929847788699196 1.0842205199620274 1.3702368842826 1.1339096678848637 1.0 13.043689645880288 -6.74387057434442 2.146816606163042 1.1737695832531632 0.7719792955360625 0.752108869063127 0.09968628435886186 0.14266006123177172 1.3518507606319774 0.038173653753211974 0.035562624736640305 1.8035551447135289e-07 6.74387057434442 -0.4017902877171007 RVS(ph)FADPIYQAGLADDIDRR ddPTM_PC-9_Lapatinib_30min_R1 1 RVSFADPIYQAGLADDIDRR 20 2 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 RVS(0.999)FADPIY(0.001)QAGLADDIDRR 56.403999999999996 0.006667 1827800.0 2923.9 3784.3 4722.7 3380.6 4123.9 5622.0 4541.5 4269.5 6155.2 4620.6 True False 2882.2046498224113 3775.5376858567 4334.417836149191 3629.220601351007 3881.3403098993494 5381.560165522095 4776.636648269837 4467.876556576045 5461.936558870525 5419.264553437507 0.5318442422217962 0.6966882034688322 0.7998166159649497 0.6696887678327029 0.7162116319708671 0.9930425267960954 0.8814178752797659 0.8244433377481111 1.0078741321838496 1.0 12.403881361868361 -3.919705334070541 0.22239434275261863 1.0254317587321293 2.3623764825524125e-11 0.7235492100739594 0.08022690288696471 10.343536078990985 0.32999877566527414 0.1422099975554643 3.101575170473627 0.00012030804398689801 3.919705334070541 -1.0254317587085056 RVS(ph)FADTIK ddPTM_PC-9_AZD4547_30min_R2 2 RVSFADTIK 9 1 Q8NG31-2;Q8NG31;Q8NG31-4;E9PPJ1;Q8NG31-3 Q8NG31-2 CASC5 Protein CASC5 1 RVS(1)FADTIK;RVS(1)FADTIK 72.937 0.014185 11029100.0 48924.0 40606.0 61893.0 63681.0 82561.0 60598.0 47506.0 87796.0 60690.0 61512.0 True False 64480.814317583005 53731.095406391076 61072.25837983224 49000.32931164233 71098.8302565955 56808.79748048773 51733.94196868353 74229.14555137411 63897.949498909366 59358.483602795655 1.086294837803877 0.9051965640823826 1.028871606432949 0.8254983338107802 1.1977871728051843 0.9570459693787083 0.871550936423298 1.2505229420631305 1.0764754357016613 1.0 15.8571666162745 -7.757098646963015 24.99999592914697 1.1226243817591806 0.9819667770884823 0.19695249390638814 0.11678020982628884 155.23021361826363 894048.5693273648 0.054781838470481646 0.030203241192434005 1.7494492682892172e-08 7.757098646963015 -0.1406576046706982 RVS(ph)FADTIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVSFADTIK 9 1 Q8NG31-2;Q8NG31;Q8NG31-4;E9PPJ1;Q8NG31-3 Q8NG31-2 CASC5 Protein CASC5 1 RVS(1)FADTIK 71.976 0.015371000000000001 3404900.0 19205.0 20617.0 24559.0 22370.0 26156.0 19336.0 17671.0 24095.0 16774.0 15248.0 True False 22456.027183959843 22663.719506993773 25144.57970052616 21116.681424518534 21030.919562417046 18321.986120917394 15997.074953039006 23462.531780762798 17019.28801670973 18012.341696898406 1.246702264582656 1.2582328210493754 1.3959639520305054 1.1723451497788693 1.1675838664574312 1.017190681213443 0.8881174487042729 1.3025808734687103 0.9448681522425442 1.0 14.136698130748739 -6.311737986670321 1.8775135630748554 1.0437476630729356 1.2910101921969201 0.4993787195134015 0.11305707847278021 0.30217815355651023 2.098065050199602 0.0395732190759383 0.05008987533866408 4.878227086786806e-07 6.311737986670321 0.2472625291239845 RVS(ph)FADTIK ddPTM_PC-9_Lapatinib_30min_R1 1 RVSFADTIK 9 1 Q8NG31-2;Q8NG31;Q8NG31-4;E9PPJ1;Q8NG31-3 Q8NG31-2 CASC5 Protein CASC5 1 RVS(1)FADTIK 69.602 0.018302000000000002 2349300.0 20129.0 16497.0 21378.0 22851.0 20881.0 16947.0 16065.0 11993.0 23225.0 26120.0 True False 19841.95676879348 16458.802210072663 19620.383361466414 24531.53876870137 19652.820633625528 16222.216315386519 16896.7670933513 12550.23856259902 20609.155929907713 30634.80719728774 0.6476932151396139 0.5372582273515939 0.6404604812790697 0.8007734016642767 0.6415193184361054 0.5295354467523059 0.5515545433185315 0.40967251668259747 0.6727365965512703 1.0 14.902884151171786 -11.040039553712996 2.9470622532632493 1.0150948141704075 0.6001289745373766 0.5889419394206421 0.09934863538015204 36195989.78244473 40841597.264025 4394095.411630443 0.02679702505460713 9.119277810306619e-12 11.040039553712996 -0.4149658396330309 RVS(ph)FGVDEEER ddPTM_PC-9_AZD4547_30min_R2 2 RVSFGVDEEER 11 1 J3QTB2;J3QTA6;Q9BRQ6 J3QTB2 CHCHD6 MICOS complex subunit MIC25 1 RVS(1)FGVDEEER;RVS(1)FGVDEEER 95.822 0.0027779 6524200.0 17107.800000000003 14377.8 21408.0 17550.9 19074.1 18250.2 14498.7 19724.4 16588.1 19707.2 True False 22547.724535654226 19025.14267679676 21124.115932261288 13504.811163701941 16425.990457932017 17109.01210895404 15789.0562122964 16676.447201621082 17464.913100722653 19017.25692640483 1.185645470475159 1.000414662872908 1.1107866930551458 0.7101345486346645 0.8637413125089074 0.8996571995195978 0.8302488772907002 0.876911284637817 0.9183718329257676 1.0 14.215021544566516 -5.737542352359276 24.9999705855334 0.8653230619813945 1.0890956667997536 0.6240581064735441 0.08077010037617088 146.62563090202903 153391.75478998592 0.020987721866742252 0.036327463229177466 1.830027633476701e-06 5.737542352359276 0.22377260481835903 RVS(ph)FGVDEEER ddPTM_PC-9_Lapatinib_30min_R1 2 RVSFGVDEEER 11 1 J3QTB2;J3QTA6;Q9BRQ6 J3QTB2 CHCHD6 MICOS complex subunit MIC25 1 RVS(1)FGVDEEER;RVS(1)FGVDEEER 92.26899999999999 0.0035476999999999996 6062500.0 20351.8 17882.9 18270.8 16722.0 19631.9 18329.3 15276.0 15220.400000000001 20039.0 15652.099999999999 True False 20061.579599936966 17841.493243772093 16768.645351327563 17951.791662956737 18477.19023980043 17545.398566685202 16066.91653395794 15927.59534880198 17781.996799975073 18357.544629887732 1.0928247761018601 0.971888866593005 0.9134470698236354 0.9778972092885236 1.0065175170386298 0.9557595484812123 0.8752214339056845 0.8676321191054289 0.9686478861135048 1.0 14.164085486930075 -7.014140792420787 7.75337192132784 0.9165468224897159 0.9857541103130829 0.21630862051604338 0.055819428889252114 0.2412415833115171 88.14461697998544 0.020955490084376867 0.017122856870772588 9.679640044996248e-08 7.014140792420787 0.06920728782336705 RVS(ph)GDAAQDLDR ddPTM_PC-9_AZD4547_30min_R2 3 RVSGDAAQDLDR 12 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 RVS(1)GDAAQDLDR;RVS(1)GDAAQDLDR;RVS(1)GDAAQDLDR 110.6 0.00053806 110351000.0 126289.0 120459.0 166782.0 200830.0 167118.0 133582.0 152552.0 159031.0 161590.0 178054.0 True False 166446.27502561634 159395.01604586656 164570.36170657727 154531.74629256956 143916.5503666588 125229.09642295963 166128.8324676171 134456.41311882756 170131.31750747687 171820.38365541943 0.9687225199043863 0.9276839723832094 0.9578046457899788 0.8993795905058523 0.8375988186318981 0.7288372529426007 0.9668749943009289 0.7825405243447473 0.990169582257889 1.0 17.390541673044552 -5.922511929924701 4.178722722862999 0.8696214641677114 0.9485594492685941 0.09802430884136137 0.08391268799368552 0.41088337790313606 13.8155701241286 0.023246495111529746 0.035285470556653514 1.1953306898869873e-06 5.922511929924701 0.07893798510088279 RVS(ph)GDAAQDLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RVSGDAAQDLDR 12 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 RVS(1)GDAAQDLDR;RVS(1)GDAAQDLDR 109.55 0.0019077000000000002 64931000.0 144677.0 138798.0 153006.0 155111.0 262009.0 215943.0 159622.0 248835.0 181799.0 157269.0 True False 169167.95859899788 152576.94815597415 156654.24331848646 146420.63354664715 210670.21729734377 204618.5689340746 144501.44859679695 242303.34491247602 184457.4664450824 185780.62475928097 0.9105791242665461 0.8212748146028179 0.8432216412312423 0.7881372653169123 1.1339730263600558 1.1013988633055911 0.7778068826285296 1.3042444292909041 0.9928778454916221 1.0 17.503240523943973 -6.257089367525637 24.89771137541562 1.0557176673066075 0.8395810648584265 0.39656731292284575 0.12739682442958775 362.81837511217003 2076623.4165631144 0.03738347730022468 0.04657584892134166 5.532362545744649e-07 6.257089367525637 -0.216136602448181 RVS(ph)GDAAQDLDR ddPTM_PC-9_Lapatinib_30min_R1 3 RVSGDAAQDLDR 12 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 RVS(1)GDAAQDLDR;RVS(1)GDAAQDLDR;RVS(1)GDAAQDLDR 164.7 0.00053941 111341000.0 214050.0 191194.0 225642.0 178024.0 197166.0 194412.0 182568.0 189359.0 238747.0 193856.7 True False 210997.60774803773 190751.30203992475 207090.5857633079 191116.47883065505 185569.08352327053 186097.45195650702 192020.47772791548 198157.31042901552 211856.7987426344 227364.57229718447 0.9280144466493498 0.8389666873456295 0.9108304942628582 0.8405728161591062 0.8161741367547635 0.8184980187382145 0.8445488045381525 0.8715399608079986 0.9317933598983041 1.0 17.794647946991446 -8.465754791401457 1.9942759910378178 0.9991041265938643 0.8545336684465914 0.635101979511033 0.03457527584403678 0.20391381137759643 1.7859122560593665 0.034105407962117966 0.009599070670656991 3.42172583299482e-09 8.465754791401457 -0.14457045814727287 RVS(ph)GPDPKPGSNCSPAQSVLSEVPSVPTNGMAK ddPTM_PC-9_Lapatinib_30min_R1 1 RVSGPDPKPGSNCSPAQSVLSEVPSVPTNGMAK 33 2 P22314;Q5JRR9;Q5JRS2;Q5JRS3;Q5JRS0;Q5JRS1 P22314;Q5JRS0 UBA1 Ubiquitin-like modifier-activating enzyme 1 1 RVS(0.64)GPDPKPGS(0.042)NCS(0.042)PAQS(0.126)VLS(0.148)EVPS(0.001)VPTNGMAK 40.872 0.016829 16520000.0 50937.0 46505.0 49540.0 45383.0 62312.0 52166.0 55542.0 52846.0 60334.0 41527.0 True False 50210.62903929824 46397.32052975869 45467.01242993013 48720.61721324994 58646.930670105525 49934.98178488537 58417.69299090683 55301.41808380789 53538.54957481389 48704.88661875069 1.0309156334216343 0.9526214667728307 0.9335205476574496 1.000322977745999 1.204128266002929 1.0252560934134505 1.1994215990725015 1.1354388013813306 1.099243901210568 1.0 15.57177890641485 -6.092025421419468 6.573323994538017 1.1171520120873442 0.9697732191764885 0.4943910241210222 0.06522705987350357 0.18259935917603376 10.969632363663633 0.018265251175029095 0.023771213319047253 8.09048540150978e-07 6.092025421419468 -0.14737879291085565 RVS(ph)LSEIGFGK ddPTM_PC-9_AZD4547_30min_R2 2 RVSLSEIGFGK 11 1 E5RGN0;A0A087WZU2;Q00536;Q00536-3;Q00536-2;E5RJM2;H0YBX5 E5RGN0 CDK16 Cyclin-dependent kinase 16 1 RVS(0.985)LS(0.015)EIGFGK;RVS(0.99)LS(0.01)EIGFGK 123.1 0.00027702 39547000.0 330740.0 294360.0 360670.0 448200.0 451320.0 432310.0 329080.0 392340.0 345100.0 361610.0 True False 435908.44018063607 389506.11347646307 355887.28014240816 344874.4146209715 388662.0083502689 405277.5873591484 358367.48248756817 331712.8680762913 363341.28146438673 348950.143965518 1.2491997717121188 1.1162228192545256 1.0198800209624663 0.9883200238915814 1.1138038343628685 1.1614197453926156 1.0269876332906192 0.9506024680393024 1.0412412424747153 1.0 18.412661401439856 -4.854631862112103 2.6191499054240266 1.0413756001705579 1.2740955843896342 0.5578296673127388 0.05775485167894025 0.3377659439008839 3.4556527681288634 0.016674519603288158 0.1635396486806949 1.397552520783568e-05 4.854631862112103 0.23271998421907636 RVS(ph)LSEIGFGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RVSLSEIGFGK 11 1 E5RGN0;A0A087WZU2;Q00536;Q00536-3;Q00536-2;E5RJM2;H0YBX5 E5RGN0 CDK16 Cyclin-dependent kinase 16 1 RVS(0.866)LS(0.134)EIGFGK;RVS(0.995)LS(0.005)EIGFGK 97.223 0.0025119 22403100.0 187326.0 173309.0 162246.0 183024.0 205844.0 186884.0 193176.0 178627.0 174023.0 141733.0 True False 219036.5919428518 190513.97216072126 166114.5599613814 172769.75865181373 165510.34586351758 177083.4740495206 174876.97080687393 173938.23052095127 176567.7571558294 167428.0709421891 1.3082429410447098 1.1378854877119347 0.9921547744448346 1.0319043734994058 0.988545976383293 1.0576689622773314 1.0444901492489682 1.0388833219072926 1.0545887327149348 1.0 17.35318190443961 -4.874762624895544 2.5806328138012677 1.0283468407844822 1.3379338435535932 0.9239509551912647 0.025004645896037476 0.09712968040818142 0.986345622896895 0.006630976153226058 0.060821626546999505 1.334250502704543e-05 4.874762624895544 0.309587002769111 RVS(ph)LSEIGFGK ddPTM_PC-9_Lapatinib_30min_R1 2 RVSLSEIGFGK 11 1 E5RGN0;A0A087WZU2;Q00536;Q00536-3;Q00536-2;E5RJM2;H0YBX5 E5RGN0 CDK16 Cyclin-dependent kinase 16 1 RVS(0.953)LS(0.047)EIGFGK;RVS(0.958)LS(0.042)EIGFGK 121.92 0.00033007 27103000.0 358820.0 308260.0 314520.0 270550.0 332150.0 314860.0 303520.0 277360.0 352720.0 282070.0 True False 353703.1610004713 307546.24290943774 288661.37968230987 290447.14952834276 312613.59003202536 301394.1717745087 319234.7804652337 290247.15815246117 312992.95929373783 330825.4236653512 1.0691535042308666 0.9296330357625064 0.8725489609719577 0.8779468830126752 0.9449503202276615 0.911036910148073 0.9649644725858734 0.877342360622389 0.9460970557400331 1.0 18.335710583149528 -8.543560394529838 21.900484925062642 1.0000000039760415 0.9271015423242511 0.12182347704038632 0.0548302488929217 1781.8429928225146 1886853.551087094 0.052976805213743663 0.013678552308063967 2.860484543848425e-09 8.543560394529838 -0.07289846165179037 RVS(ph)LTQR ddPTM_PC-9_AZD4547_30min_R2 3 RVSLTQR 7 1 Q96I34 Q96I34 PPP1R16A Protein phosphatase 1 regulatory subunit 16A 1 RVS(0.993)LT(0.007)QR;RVS(0.984)LT(0.016)QR;RVS(0.807)LT(0.193)QR 89.88600000000001 0.007471800000000001 13590700.0 23934.1 29152.699999999997 54800.7 90605.0 62421.0 36536.6 34008.0 69906.5 34169.8 46532.0 True False 31544.645939793638 38575.740162879796 54074.0069118587 69717.41708329575 53754.921614890045 34251.96062618549 37034.64611777438 59104.05671656034 35975.94586897074 44902.92884323851 0.702507536867356 0.8590918489426896 1.2042423134721907 1.552625160080038 1.197136200236624 0.7628001448583273 0.8247712804451298 1.316262841626649 0.8011937482868225 1.0 15.454521928965953 -6.732471701550115 24.994475675984145 0.9535071146181886 1.1201538017928594 0.08864951134417853 0.25544182918214764 607.7801814226398 524415.7024213935 0.09246288822323287 0.09244859803537604 1.8515195345264276e-07 6.732471701550115 0.1666466871746708 RVS(ph)LTQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RVSLTQR 7 1 Q96I34 Q96I34 PPP1R16A Protein phosphatase 1 regulatory subunit 16A 1 RVS(0.969)LT(0.031)QR;RVS(0.994)LT(0.006)QR;RVS(0.957)LT(0.043)QR 80.755 0.011434 10603300.0 33460.0 21759.6 48339.0 40178.0 55173.0 45137.0 31886.1 45238.7 44552.0 33125.3 True False 39124.11713487614 23919.74928381344 49491.58508667836 37926.95691883352 44362.24671269442 42769.93626085274 28865.617772627305 44051.23205936477 45203.488715896725 39130.654670269505 0.9998329305898802 0.6112790467057293 1.2647778449840459 0.9692390080979013 1.1336954898022635 1.0930033402520165 0.7376727533914397 1.1257473822137147 1.1551937757443451 1.0 15.256011626809633 -5.259049852917462 24.9999843571003 1.0534766675773164 0.8055560087187809 0.2893816737067465 0.15918228535624132 256.9994754148501 2688767.7518976876 0.039950393990841805 0.09594047294968686 5.507444724967603e-06 5.259049852917462 -0.24792065885853554 RVS(ph)LTQR ddPTM_PC-9_Lapatinib_30min_R1 3 RVSLTQR 7 1 Q96I34 Q96I34 PPP1R16A Protein phosphatase 1 regulatory subunit 16A 1 RVS(0.959)LT(0.041)QR;RVS(0.997)LT(0.003)QR;RVS(0.996)LT(0.004)QR 73.233 0.016872 12426000.0 57851.0 52017.0 41245.2 27548.0 27447.4 28236.5 22256.4 20233.699999999997 43418.0 20891.4 True False 57026.03413142593 51896.557832414954 37854.178867076174 29573.971817434052 25832.997895664623 27028.890717496397 23408.727490598427 21173.83156875343 38527.80762819088 24502.45065395932 2.3273604316885406 2.118014992268908 1.544913992550348 1.2069801602745083 1.0543026189704947 1.1031096888722367 0.9553627031513209 0.864151584989805 1.572406294060436 1.0 14.580638429573268 -5.363849635430266 1.4914158480005402 1.07555781712244 2.3887514978873656 0.8635238507041044 0.17753979850975887 0.16361484474056204 0.6267073172222989 0.05298864300128838 0.22782867390050987 4.326636050213678e-06 5.363849635430266 1.3131936807649256 RVS(ph)LVGADDLR ddPTM_PC-9_AZD4547_30min_R2 2 RVSLVGADDLR 11 1 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 RVS(1)LVGADDLR;RVS(1)LVGADDLR 146.84 0.00011038 22763000.0 65979.0 111696.0 89391.0 113625.0 109897.0 85634.0 83293.0 121950.0 76369.0 74926.0 True False 86958.94955154545 147799.54766567136 88205.61693295822 87430.51173875028 94639.69851030239 80279.29244272235 90705.91564007851 103105.42963221628 80405.7094295964 72302.86354569942 1.2027040878758912 2.044172808899247 1.2199463839659321 1.2092261281393004 1.3089343059073288 1.1103196817644903 1.2545272924459947 1.4260213852670984 1.1120681185576493 1.0 16.141765165610636 -5.3994324184517355 22.108915626638154 1.2225244114070881 1.6256801693559202 0.36712140639298896 0.21873323013042825 6.2577477203342315 1099.1143338605561 0.052293356278328644 0.10885737007102243 3.9862779886214025e-06 5.3994324184517355 0.40315575794883207 RVS(ph)LVGADDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RVSLVGADDLR 11 1 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 RVS(1)LVGADDLR;RVS(1)LVGADDLR;RVS(1)LVGADDLR 78.508 0.0083953 12245300.0 63161.0 66923.0 56965.0 45354.0 85197.0 41076.8 36470.5 40445.7 31692.2 29655.9 True False 73852.90981338649 73566.67316130093 58323.26164096552 42812.96241965193 68503.25944178192 38922.66029642636 33015.75021644554 39384.04323076144 32155.63846924812 35032.27991402478 2.108138836371318 2.099968181969491 1.6648434467896693 1.222100374989075 1.9554325213745911 1.1110513044526145 0.9424379542944922 1.1242215273289844 0.9178859768237627 1.0 15.09639726188363 -5.389493083931088 0.3946973620804905 0.8992221584851812 2.7175616760341925 0.7462720850612299 0.234155008120833 1.8498732334937706 0.32510733130688124 0.21667414833096024 1.5235649990242557 4.078560567608506e-06 5.389493083931088 1.8183395175490114 up RVS(ph)LVGADDLR ddPTM_PC-9_Lapatinib_30min_R1 2 RVSLVGADDLR 11 1 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 RVS(1)LVGADDLR;RVS(1)LVGADDLR 89.13600000000001 0.0043308 20029100.0 93055.0 151401.0 68237.0 43591.0 61832.0 46025.0 45373.0 39788.0 71232.0 40882.0 True False 91728.01863580298 151050.4402865495 62626.81726243733 46796.82755531319 58195.16332638919 44056.61803951521 47722.19192820595 41636.695733235196 63209.102053786344 47948.399228159135 1.913056955234763 3.1502707643645507 1.3061294698167496 0.9759831049339881 1.2137039872691378 0.9188339704496671 0.9952822762887914 0.8683646670895073 1.3182734579523754 1.0 15.549195030785631 -5.3942761241977495 5.507673316525557 1.0439879231531124 2.5183617134586873 0.7859388915650245 0.3063070903865606 0.08256187713651116 3.3166572382610813 0.0738616854605143 0.1571739695116672 4.033888370118096e-06 5.3942761241977495 1.474373790305575 RVS(ph)PLNLSSVT(ph)P ddPTM_PC-9_AZD4547_30min_R2 1 RVSPLNLSSVTP 12 1 Q9UJX2-3;Q9UJX2 Q9UJX2-3 CDC23 Cell division cycle protein 23 homolog 2 RVS(1)PLNLS(0.001)S(0.002)VT(0.997)P 88.10799999999999 0.028144 0.0 6726.3 6683.3 10722.0 12858.0 12887.0 11325.0 7068.6 11920.0 6652.2 9924.7 True False 8865.123484268637 8843.546025945265 10579.819274369655 9893.786754119714 11097.862495812127 10616.845959710281 7697.691706307346 10078.037894350306 7003.821711264537 9577.239273843577 0.9256449829420258 0.9233919893907105 1.1046836120367407 1.0330520592860888 1.1587746926320956 1.1085497246274274 0.8037485006071146 1.0522904989827768 0.7312986040134438 1.0 13.225394130609818 -7.253107629540515 24.83251488486753 0.9011919406756242 1.044645160430319 0.2959080529625975 0.10984740538605567 751.8273906970438 2240801.681285768 0.04245805047297623 0.03233887027328506 5.583318083529e-08 7.253107629540515 0.14345321975469483 RVS(ph)PLNLSSVTP ddPTM_PC-9_AZD4547_30min_R2 1 RVSPLNLSSVTP 12 1 Q9UJX2-3;Q9UJX2 Q9UJX2-3 CDC23 Cell division cycle protein 23 homolog 1 RVS(0.974)PLNLS(0.026)SVTP 125.82 0.00041399 3625400.0 16430.0 17428.0 24714.0 33532.0 27658.0 23485.0 21135.0 27007.0 19959.0 22998.0 True False 21654.398234770044 23061.260176884785 24386.27621215925 25801.715464235655 23818.16411183143 22016.479237421278 23015.97405607981 22833.688709120688 21013.99199289391 22192.847020046393 0.9757377327573169 1.0391303178025773 1.098834962009677 1.1626140368979896 1.073236078738204 0.992052944695838 1.0370897449655694 1.0288760467954128 0.9468813070225895 1.0 14.437807135783439 -6.753886518064156 24.562162061455204 1.0050416187529345 1.0749577241200137 0.3221130256148905 0.04955485280620648 185.15621613465066 602133.9485277915 0.017937914820576925 0.017596697312757592 1.7624365141063295e-07 6.753886518064156 0.06991610536707915 RVS(ph)PLNLSSVTP ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RVSPLNLSSVTP 12 1 Q9UJX2-3;Q9UJX2 Q9UJX2-3 CDC23 Cell division cycle protein 23 homolog 1 RVS(1)PLNLSSVTP;RVS(0.959)PLNLS(0.04)S(0.001)VTP;RVS(0.999)PLNLS(0.001)SVTP 121.21 0.0006718999999999999 90744000.0 79092.0 79881.0 89861.0 95114.0 107823.0 94043.0 102357.0 88248.0 91253.0 67005.0 True False 92480.71346179397 87811.05776486243 92003.62703974033 89785.07094374853 86695.85716388203 89111.21952676027 92661.00395949362 85931.58350648488 92587.40249128504 79152.47608871173 1.1683868658529943 1.1093911663160914 1.1623594306339249 1.1343305399962487 1.0953018963893928 1.1258172066138155 1.1706646277956225 1.085646182567622 1.16973475836076 1.0 16.27234686175057 -11.545585308918032 2.7332460580507556 0.8456738426489578 1.1337767375490937 0.644593585098505 0.03020547596108482 6615370.493633107 2820554.330987389 6437202.884590623 0.007085489817318555 2.847178471004189e-12 11.545585308918032 0.28810289490013585 RVS(ph)PLNLSSVTP ddPTM_PC-9_Lapatinib_30min_R1 4 RVSPLNLSSVTP 12 1 Q9UJX2-3;Q9UJX2 Q9UJX2-3 CDC23 Cell division cycle protein 23 homolog 1 RVS(0.999)PLNLSS(0.001)VTP;RVS(0.979)PLNLS(0.021)SVTP;RVS(1)PLNLSSVTP;RVS(0.989)PLNLS(0.011)SVTP 113.95 0.0011625 91250800.0 144334.0 118565.0 135469.0 115098.0 114936.0 120602.0 107814.0 99923.0 123122.0 83323.0 True False 142275.77069238634 118290.47002711185 124331.26174546212 123562.6908756723 108175.69045287029 115444.13359699318 113396.08138204654 104565.78736684575 109254.7038278621 97725.26952908142 1.4558749377513607 1.2104389232910795 1.2722529428119225 1.2643883354949672 1.1069367316575065 1.1813130232671185 1.1603557803266202 1.0699974312757328 1.1179780250731335 1.0 16.576444038063585 -1.5228787452803454 0.18892924050233278 1.0062923540926743 2.705620760213529 0.7879364024409058 0.055753726020616776 24.862508863360055 0.2895043308452154 0.11188098170010655 12.296402737680395 0.029999999999999458 1.5228787452803454 1.699328406120855 RVS(ph)PVPFQSGR ddPTM_PC-9_AZD4547_30min_R2 1 RVSPVPFQSGR 11 1 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 RVS(1)PVPFQSGR 75.02 0.010172 2769500.0 19634.0 15461.0 16880.0 19144.0 18517.0 22830.0 14762.0 17248.0 19378.0 18541.0 True False 25877.20358742999 20458.465893666274 16656.16017080393 14730.646571851597 15946.234176686048 21402.436490965614 16075.789402216711 14582.717919610244 20402.281519028915 17891.88523344119 1.446309500077928 1.1434494256327983 0.9309337698898492 0.8233143897166848 0.8912551119477011 1.1962091312190488 0.8984961166736042 0.8150464710311309 1.1403092101717498 1.0 14.127017788942656 -4.866435967729147 2.430372684255146 0.9546780896406355 1.5098178646051983 0.611721005739756 0.11857931871104771 0.2959713274322145 2.537205896614382 0.03178899566801778 0.3241646962098496 1.3600786781656922e-05 4.866435967729147 0.5551397749645628 RVS(ph)QDLEVEKPDASPTSLQLR ddPTM_PC-9_AZD4547_30min_R2 2 RVSQDLEVEKPDASPTSLQLR 21 2 O94885 O94885 SASH1 SAM and SH3 domain-containing protein 1 1 RVS(1)QDLEVEKPDASPTSLQLR;RVS(1)QDLEVEKPDASPTSLQLR 65.28699999999999 0.012248 20950000.0 18897.4 18245.9 17351.8 25393.0 26620.0 24799.0 21501.0 24851.0 20271.3 25562.0 True False 24906.380109661786 24143.53035697854 17121.703794535297 19539.03616793917 22924.272494647223 23248.314609700254 23414.547347043863 21010.848969169423 21342.79953332084 24667.08216046725 1.00970110480185 0.9787752844019881 0.6941114349542091 0.7921097453209707 0.929346744196071 0.9424833654204636 0.9492224169330102 0.8517768268045299 0.8652340554297874 1.0 14.590299450615712 RVS(ph)QDLEVEKPDASPTSLQLR ddPTM_PC-9_Lapatinib_30min_R1 1 RVSQDLEVEKPDASPTSLQLR 21 2 O94885 O94885 SASH1 SAM and SH3 domain-containing protein 1 1 RVS(0.999)QDLEVEKPDASPTSLQLR 43.848 0.027249000000000002 7172000.0 19232.0 20836.0 21170.0 17703.0 20964.0 19355.0 20350.0 18601.0 23389.0 16414.0 True False 18957.74815328315 20787.755522160023 19429.484318563205 19004.9376754768 19730.938736809807 18527.231768708676 21403.623426685263 19465.27036628903 20754.68452291116 19251.138029719797 0.9847598684304423 1.0798195665143537 1.009264194592968 0.9872111272661952 1.02492323863396 0.9623967029952433 1.1118108131395905 1.0111231001636711 1.0781016940853156 1.0 14.232656112697448 -7.250848863906599 24.99753617525888 1.0511858297080334 1.0111973773623961 0.19683787649100093 0.041450929895798 1216.2142532619869 2870717.634922318 0.015314102734806061 0.011725470105236386 5.612432567900473e-08 7.250848863906599 -0.039988452345637304 RVS(ph)SGSCFALE ddPTM_PC-9_AZD4547_30min_R2 1 RVSSGSCFALE 11 1 Q9NZJ7-3;Q9NZJ7-2;Q9NZJ7 Q9NZJ7-3 MTCH1 Mitochondrial carrier homolog 1 1 RVS(0.435)S(0.435)GS(0.13)CFALE 82.85 0.019811000000000002 10495000.0 45500.0 39322.0 75879.0 52226.0 59220.0 44758.0 65069.0 70298.0 46273.0 51985.0 True False 59968.05354120735 52032.06751637959 74872.79488154218 40186.102583656546 50998.32521160815 41959.27518452209 70860.01494464427 59435.05938733538 48718.89631179819 50165.0209730025 1.195415697592962 1.037218095540753 1.4925299228288325 0.8010781577323302 1.0166112606442268 0.8364249505069175 1.412538329900814 1.184790880867403 0.971172649125721 1.0 15.614394132999003 -5.76659736179027 24.99999695745382 1.0465923019373755 1.2212709027167767 0.19339085180011661 0.1934803008145984 255.86217977048204 1240134.8551385577 0.055980293476082355 0.08595501598994398 1.7116014203661714e-06 5.76659736179027 0.17467860077940123 RVS(ph)SGSCFALE ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVSSGSCFALE 11 1 Q9NZJ7-3;Q9NZJ7-2;Q9NZJ7 Q9NZJ7-3 MTCH1 Mitochondrial carrier homolog 1 1 RVS(0.369)S(0.369)GS(0.263)CFALE 84.605 0.017506999999999998 7611900.0 51363.0 38859.0 53009.0 35513.0 63369.0 42688.0 39642.0 45820.0 41819.0 39987.0 True False 60057.74143450818 42716.66470981575 54272.93559775202 33523.321744699424 50952.299348172746 40449.366132070856 35886.82277677397 44617.273550302976 42430.52376122477 47236.32656308214 1.2714312437971562 0.9043180919830721 1.1489660510597237 0.7096936655294401 1.0786676919113953 0.8563190466992054 0.7597293309599048 0.944554261447881 0.8982604458998432 1.0 15.527609154291113 -1.5451689881325648 0.9273031208112776 0.9006442164113166 199.99999996031514 0.38804117998609444 0.1282943099825243 1005.8301782275715 2.0664869520524256 0.03992261361624045 424195.80402393726 0.028499091248577198 1.5451689881325648 199.09935574390383 RVS(ph)TDLPEGQDVYTAACNSVIHR ddPTM_PC-9_AZD4547_30min_R2 2 RVSTDLPEGQDVYTAACNSVIHR 23 1 Q15751;H0YNB1 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 RVS(0.677)T(0.323)DLPEGQDVYTAACNSVIHR;RVS(0.914)T(0.086)DLPEGQDVYTAACNSVIHR 100.12 2.6685000000000004e-06 21379100.0 27594.2 24921.0 33422.0 52678.0 47007.0 35657.0 30368.0 53827.0 39783.0 45300.0 True False 36368.58160498427 32976.22589328354 32978.80244245313 40533.90096698697 40480.88944988284 33427.36215323526 33070.69316938878 45509.27397140892 41885.848161395785 43714.06078824689 0.8319652978741899 0.7543619901391004 0.7544209311096517 0.9272508715979333 0.9260381835943886 0.7646821537619003 0.7565230173784331 1.041067179547975 0.9581779273331055 1.0 15.415809782082725 -7.765340475798616 24.99999162837101 0.9997169480412598 0.818172359940447 0.6269933494463471 0.06477399645860532 72.7056620918548 465916.67751809186 0.037076425995433766 0.01885932915571843 1.716562118580508e-08 7.765340475798616 -0.18154458810081275 RVS(ph)TDLPEGQDVYTAACNSVIHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RVSTDLPEGQDVYTAACNSVIHR 23 1 Q15751;H0YNB1 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 RVS(0.751)T(0.249)DLPEGQDVYTAACNSVIHR;RVS(0.5)T(0.5)DLPEGQDVYTAACNSVIHR 121.62 5.2509e-09 25180000.0 25109.4 24889.9 35804.0 42075.0 49629.0 45712.0 37454.0 36922.0 43094.0 29337.3 True False 29359.925486744156 27360.804780381455 36657.70314742617 39717.674158990456 39904.55371475746 43314.78224862308 33906.08597652216 35952.836622092706 43724.16822416174 34655.92025606099 0.8471835481445449 0.7894987228220064 1.0577616429335788 1.1460574085330835 1.1514498365622978 1.2498523175429956 0.9783634578450505 1.037422649765155 1.2616651902791356 1.0 15.080814207943112 -5.351103134652023 3.929726725362591 1.1193348395224956 0.8168858752912391 0.6270260905629581 0.0908039823599246 0.13788299294537107 3.8706215566487607 0.024411685308955784 0.056266272764913534 4.455504281604689e-06 5.351103134652023 -0.30244896423125645 RVS(ph)TDLPEGQDVYTAACNSVIHR ddPTM_PC-9_Lapatinib_30min_R1 6 RVSTDLPEGQDVYTAACNSVIHR 23 1 Q15751;H0YNB1 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 RVS(0.5)T(0.5)DLPEGQDVYTAACNSVIHR;RVS(0.751)T(0.249)DLPEGQDVYTAACNSVIHR;RVS(0.5)T(0.5)DLPEGQDVYTAACNSVIHR;RVS(0.5)T(0.5)DLPEGQDVYTAACNSVIHR;RVS(0.5)T(0.5)DLPEGQDVYTAACNSVIHR;RVS(0.766)T(0.234)DLPEGQDVYTAACNSVIHR 128.18 2.5071e-07 63871900.0 139973.0 112033.4 175815.0 135598.0 146580.0 155563.0 118835.0 111346.0 168265.0 107857.2 True False 137976.95935209523 111773.9935456116 161360.16936552586 145570.32926166742 137958.45258736785 148909.93312506477 124987.69483587923 116519.5416485575 149313.2237909978 126500.17330931492 1.0907254570688814 0.8835876712382421 1.2755727138094284 1.1507520144318115 1.0905791587339209 1.1771520088036092 0.9880436648119254 0.921101834095096 1.180340072941252 1.0 16.94877983589646 -7.277909320670386 24.133993327946804 1.0157965407867027 1.109345396428218 0.1330264009525638 0.11075676645917859 1121.5505590324212 1643439.9016821831 0.04694440628796444 0.03176422538941534 5.2733995686242664e-08 7.277909320670386 0.09354885564151538 RVS(ph)VCAETYNPDEEEEDTDPR ddPTM_PC-9_AZD4547_30min_R2 4 RVSVCAETYNPDEEEEDTDPR 21 1 P13861-2;P13861 P13861-2 PRKAR2A cAMP-dependent protein kinase type II-alpha regulatory subunit 1 RVS(0.991)VCAET(0.006)Y(0.002)NPDEEEEDTDPR;RVS(1)VCAETYNPDEEEEDTDPR;RVS(0.997)VCAET(0.003)YNPDEEEEDTDPR;RVS(1)VCAETYNPDEEEEDTDPR 152.62 2.488e-06 600860000.0 39683.8 38119.899999999994 64306.0 70192.5 72457.3 72817.0 56693.8 82275.2 55277.8 57884.7 True False 52302.42292568273 50441.41219972631 63453.260423206004 54010.70358831454 62397.854599038394 68263.74147887167 61739.4383695565 69561.45833601087 58199.67165613463 55858.17427173142 0.9363432229497667 0.9030265105756166 1.1359708986284982 0.9669256880035222 1.1170765140925232 1.2220904526308236 1.1052892289177711 1.2453228062488675 1.0419186164770193 1.0 15.769480799351266 -5.3349789408801875 0.8857566610822235 1.1343620501091387 0.8729093498004982 0.37438572154753536 0.08796100024014411 1.078501168000034 1.1394767411552607 0.03305129933869626 0.23300775460898404 4.624034429906504e-06 5.3349789408801875 -0.26145270030864054 RVS(ph)VCAETYNPDEEEEDTDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RVSVCAETYNPDEEEEDTDPR 21 1 P13861-2;P13861 P13861-2 PRKAR2A cAMP-dependent protein kinase type II-alpha regulatory subunit 1 RVS(0.998)VCAETY(0.001)NPDEEEEDTDPR;RVS(0.998)VCAET(0.002)YNPDEEEEDTDPR;RVS(1)VCAETYNPDEEEEDTDPR;RVS(1)VCAETYNPDEEEEDTDPR 99.09700000000001 0.00010976 325435000.0 71353.0 65356.7 78623.0 74485.0 83499.0 76918.0 85659.0 74940.0 76742.0 56951.9 True False 83431.65361401143 71844.88124861714 80497.67049938791 70311.84693362816 67137.97035258685 72884.28467359982 77544.75940254498 72972.90440549326 77864.2065683996 67276.82863900773 1.2401246506681647 1.06789934516861 1.1965140469287017 1.045112386478644 0.9979360161703525 1.0833489947137733 1.1526220984439182 1.0846662347455376 1.1573703479128208 1.0 16.037822079574546 -2.253760004825281 1.3802241870043395 1.0877402396461893 199.9994086808431 0.3305857022656752 0.06333208799890412 2123.533422502206 4.113982252911868 0.0176665352269755 1337360.6810661827 0.0055749374005667944 2.253760004825281 198.9116684411969 RVS(ph)VCAETYNPDEEEEDTDPR ddPTM_PC-9_Lapatinib_30min_R1 6 RVSVCAETYNPDEEEEDTDPR 21 1 P13861-2;P13861 P13861-2 PRKAR2A cAMP-dependent protein kinase type II-alpha regulatory subunit 1 RVS(1)VCAETYNPDEEEEDTDPR;RVS(1)VCAETYNPDEEEEDTDPR;RVS(0.996)VCAET(0.004)YNPDEEEEDTDPR;RVS(1)VCAETYNPDEEEEDTDPR;RVS(1)VCAETYNPDEEEEDTDPR;RVS(0.966)VCAET(0.021)Y(0.013)NPDEEEEDTDPR 122.59 6.2293e-07 572547500.0 123385.0 108030.40000000001 138113.8 140838.4 146309.8 134678.5 124876.0 116411.8 175763.3 101673.8 True False 121625.50727396212 107780.26224616797 126758.61649868567 151196.12575912927 137704.14522013415 128918.61450591747 131341.46825703923 121820.71721016994 155966.98628439827 119247.98085817744 1.0199376660189516 0.9038330164629947 1.0629833359563605 1.267913508229108 1.154771294483441 1.081096833490551 1.1014146093865076 1.0215746743339182 1.307921401787851 1.0 16.863605312738407 -5.51775329575326 24.839763309452263 1.134378126343681 0.9672660209031209 0.3419968986660554 0.0948000450788292 206.08632759045616 998766.1652310304 0.024870344686223064 0.04470355617534477 3.035615098493995e-06 5.51775329575326 -0.1671121054405601 RVS(ph)VELTNSLFK ddPTM_PC-9_AZD4547_30min_R2 1 RVSVELTNSLFK 12 1 P14923 P14923 JUP Junction plakoglobin 1 RVS(1)VELTNSLFK 113.67 0.00036929 12523000.0 42996.0 58369.0 53212.0 64008.0 71243.0 70687.0 66551.0 77896.0 53487.0 72873.0 True False 56667.83362764287 77235.63778199395 52506.37411189683 49251.94451374201 61352.13919369466 66266.93071558862 72473.91007362984 65858.9630720059 56314.21362412529 70321.73845081497 0.8058366427797852 1.098318094567795 0.7466592161771042 0.7003800759019948 0.8724491251962734 0.9423391994487964 1.0306046418963342 0.9365377552215883 0.8008080412220334 1.0 16.101683115892087 -6.683497146858916 4.696264527366294 0.9436800773019455 0.8432104205144227 0.15990126783077852 0.11296693785214196 0.44810275412028333 18.094435895237645 0.040536615325664875 0.03994934773895781 2.0725396752947653e-07 6.683497146858916 -0.10046965678752273 RVS(ph)VELTNSLFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVSVELTNSLFK 12 1 P14923 P14923 JUP Junction plakoglobin 1 RVS(1)VELTNSLFK 99.915 0.0014655 8169900.0 58831.0 65231.0 75056.0 70641.0 95866.0 63649.0 83693.0 51971.0 62541.0 57686.0 True False 68789.92633478488 71706.70258333956 76845.61969146511 66683.21379121195 77081.74547983898 60311.13439233924 75764.99315515233 50606.8163178262 63455.54380905226 68144.01515787514 1.0094786192949343 1.0522817362201278 1.1276943325606836 0.9785630276807314 1.1311594319949745 0.8850540176215214 1.1118363509931286 0.7426450613539722 0.9311976064521486 1.0 16.056299335461773 -7.747019718165499 24.999996150011903 0.8776909483705577 1.040882888576963 0.3547832665998719 0.09277013291883537 216.49758832504796 375352.68545794016 0.04104553139731882 0.02355997728749838 1.7905245574438583e-08 7.747019718165499 0.16319194020640526 RVS(ph)VELTNSLFK ddPTM_PC-9_Lapatinib_30min_R1 3 RVSVELTNSLFK 12 1 P14923 P14923 JUP Junction plakoglobin 1 RVS(0.996)VELT(0.004)NSLFK;RVS(0.999)VELT(0.001)NSLFK;RVS(0.991)VELT(0.006)NS(0.003)LFK 76.156 0.008692700000000001 11514300.0 101970.0 106286.0 115800.0 89827.7 137108.0 132203.0 117499.0 120061.0 137114.0 104286.0 True False 100515.88910099235 106039.90129719223 106279.37100092683 96433.92871442271 129043.57700469946 126548.98587024512 123582.52329297765 125639.47236422951 121670.77744557033 122311.69614763946 0.8218011217803903 0.8669645229119712 0.8689223872150346 0.7884276954022424 1.055038733572414 1.034643373087484 1.0103900704950097 1.0272073425633241 0.9947599557339513 1.0 16.90020284369359 -6.265192946231397 24.999998127842225 1.0219179647533583 0.8410167183432485 0.9181037322331876 0.02687864214340118 84.16572486049978 560570.5818285034 0.008224065804926713 0.00967801466974732 5.430090324938424e-07 6.265192946231397 -0.18090124641010974 RVSS(ph)VPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVSSVPSR 8 1 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 RVS(0.226)S(0.773)VPSR 95.48299999999999 0.010346 0.0 6099.8 5947.0 6565.5 6577.2 8108.9 6764.7 5536.4 7846.1 5922.3 5165.5 True False 7132.375663458383 6537.378857646208 6722.046419797406 6208.700807570108 6520.019255225706 6409.947223426254 5011.9521119351 7640.14818863013 6008.90243360916 6101.964259924497 1.1688655258604606 1.0713564647668223 1.101620090426518 1.0174921620479846 1.0685115443967517 1.0504727576863204 0.8213670055152233 1.2520801275103937 0.9847488739115478 1.0 12.575058014532656 -1.5228913053266522 0.617074781887755 1.0304032555894445 10.537154512688518 0.1505711155580719 0.10027866993448253 382.0201466838866 2.7854872364035828 0.043059813665551935 4920.668951680343 0.029999132395283533 1.5228913053266522 9.506751257099074 RVST(ph)DLPEGQDVYTAACNSVIHR ddPTM_PC-9_AZD4547_30min_R2 1 RVSTDLPEGQDVYTAACNSVIHR 23 1 Q15751;H0YNB1 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 RVS(0.396)T(0.604)DLPEGQDVYTAACNSVIHR 97.3 6.866499999999999e-06 18492000.0 28829.0 30062.0 47397.0 67637.0 50102.0 44680.0 40978.0 52102.0 42151.0 45134.0 True False 37996.022319548734 39778.95360554916 46768.48481135033 52044.33463123311 43146.20212347165 41886.15253685259 44624.96261509527 44050.83308485232 44379.01580702801 43553.872397720406 0.8723913679266193 0.9133275967358342 1.0738077290642514 1.1949416152019836 0.9906398615827765 0.9617090336850254 1.0245923073749676 1.0114102526313578 1.01894535121407 1.0 15.410513374851718 -5.145581693742672 4.787161957621325 1.0358194947656691 0.8828411881414251 0.46900008458675535 0.06075435797395187 0.20440165440503597 7.056128555227675 0.01713126188778334 0.04936614853438794 7.151848502920799e-06 5.145581693742672 -0.15297830662424405 RVT(ph)AYTVDVTGR ddPTM_PC-9_AZD4547_30min_R2 1 RVTAYTVDVTGR 12 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 RVT(1)AYTVDVTGR 99.055 0.0029419 7050000.0 9397.9 11654.0 17075.0 18356.0 18381.0 12769.0 15138.0 19899.0 19040.0 15824.0 True False 12386.236711536534 15420.927593608869 16848.574343393197 14124.30779737296 15829.115429155172 11970.552411438463 16485.25267380818 16824.066783529932 20046.41552906961 15270.006576450736 0.8111480928003315 1.0098834939200931 1.103377019455703 0.9249706427209624 1.0366148403345607 0.7839258189907619 1.0795838620810803 1.1017720718913018 1.3127967842518817 1.0 13.898413063020875 -7.500578519695163 13.02355441611441 1.142545406961167 0.9561644864636457 0.36934847075808575 0.1156138947534645 2.0247928671996522 1183.1272443978148 0.04871561143860887 0.03195296156626684 3.158068023539386e-08 7.500578519695163 -0.1863809204975212 RVT(ph)AYTVDVTGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVTAYTVDVTGR 12 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 RVT(0.999)AYT(0.001)VDVTGR 75.445 0.016756 4430600.0 14203.0 13444.0 16108.0 18953.0 19167.0 14372.0 13045.0 17030.0 12762.0 6699.5 True False 16607.287377963115 14778.631471699291 16492.07580993018 17891.12485645507 15411.36394146076 13618.30701953998 11809.283162378702 16582.980544776517 12948.620106668031 7914.066316787179 2.0984518846823446 1.8673878737092608 2.0838940627711793 2.2606741136986344 1.9473382360684097 1.7207724164066032 1.4921890580230617 2.0953805390284623 1.6361525906349363 1.0 12.950203439244767 -6.724645469488623 3.211633628662045 1.6437207153017852 2.0662530761870928 0.4252646544378952 0.2690147535520041 0.2797798129008947 5.933264009057911 0.09420310935398363 0.08966396204435738 1.8851874091238565e-07 6.724645469488623 0.42253236088530755 RVT(ph)AYTVDVTGR ddPTM_PC-9_Lapatinib_30min_R1 1 RVTAYTVDVTGR 12 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 RVT(0.996)AYT(0.004)VDVTGR 90.561 0.0058417 4020700.0 15187.0 12858.0 16155.0 15193.0 13405.0 10618.0 8635.6 9327.6 12903.0 13790.0 True False 14970.430595045293 12828.228090993169 14826.79826010337 16310.343902362258 12616.544255244014 10163.892891766925 9082.709113684681 9760.994348077931 11449.728265386408 16173.583125980012 0.9256100196497542 0.7931593136209181 0.9167293446735825 1.0084558118826843 0.7800710675532225 0.6284255512583616 0.561576803540516 0.6035146492924387 0.7079277471294803 1.0 13.981351711139336 -6.522568446606348 4.923720759545217 0.6688539516275563 0.9031450587389637 0.3794581172808509 0.12358135355264097 0.17043224699493428 11.804238235363417 0.03936623921801934 0.041548914183834086 3.00214423322773e-07 6.522568446606348 0.23429110711140733 RVTQHES(ph)DNENEIQIQNK ddPTM_PC-9_AZD4547_30min_R2 3 RVTQHESDNENEIQIQNK 18 1 Q5VZL5-2;Q5VZL5-4;Q5VZL5 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 RVT(0.004)QHES(0.996)DNENEIQIQNK;RVT(0.047)QHES(0.953)DNENEIQIQNK;RVT(0.064)QHES(0.936)DNENEIQIQNK 134.86 2.798e-05 15051100.0 55449.0 49100.0 75076.0 118071.0 98892.0 78247.0 58529.0 88870.0 57192.0 72996.0 True False 73080.62858915166 64970.614797167946 74080.44318621309 90851.5551287657 85162.55280017485 73354.20272048136 63737.96761430306 75137.18352943897 60215.05236021788 70440.43225825309 1.0374812624831562 0.9223483262988598 1.0516750225866696 1.289764304620961 1.209000996585975 1.0413650281353417 0.9048491835005067 1.0666769229065256 0.8548364970199744 1.0 16.104116141854924 -7.004249892145364 24.860855549134808 0.9637127696462889 1.1022481755806037 0.2931702247087289 0.10626013387377324 255.28755240504015 1493379.336464971 0.04210080556251043 0.0362468889293536 9.902619862361553e-08 7.004249892145364 0.1385354059343148 RVTSGPS(ph)LGSLPPAAMES(ph)MESLRLK ddPTM_PC-9_AZD4547_30min_R2 1 RVTSGPSLGSLPPAAMESMESLRLK 25 2 Q13393-4;Q13393-2;Q13393 Q13393-4 PLD1 Phospholipase D1 2 RVT(0.319)S(0.302)GPS(0.366)LGS(0.016)LPPAAMES(0.539)MES(0.458)LRLK 48.20399999999999 0.033122000000000006 5374800.0 7244.3 8991.2 11167.0 13506.0 13218.0 11898.0 9331.9 11376.0 9692.9 9963.5 True False 9547.836709199302 11897.429567500943 11018.918283611816 10392.400365619911 11382.908859288009 11154.01617912874 10162.42102171427 9618.100594473923 10205.246905552454 9614.68089765337 0.9930476955849484 1.237423237874147 1.1460513771498309 1.080888744644282 1.1839091677047966 1.1601025866444585 1.0569691422826717 1.0003556744999604 1.0614233601911034 1.0 13.231023261310721 -7.411045771497014 4.170703283186702 1.0238163431247418 1.1384324144318279 0.40221783102003883 0.06285707882017778 0.22763738485196855 6.695735856087806 0.026969325070515204 0.017409925605283663 3.881094599053179e-08 7.411045771497014 0.11461607130708606 RVVLGDGVQLPPGDY(ph)STTPGGTLFSTTPGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 RVVLGDGVQLPPGDY(0.183)S(0.105)T(0.12)T(0.12)PGGT(0.105)LFS(0.113)T(0.113)T(0.093)PGGT(0.046)R 42.367 0.037866000000000004 0.0 8261.7 5736.1 7887.5 9008.1 5586.9 4915.2 4440.5 5028.4 4210.6 4453.9 True False 9660.242633987042 6305.5420994357555 8075.567913510321 8503.405361654242 4492.187050897224 4657.438259284922 4019.8636935640175 4896.409828030195 4272.17205932741 5261.356812946997 1.8360744152944335 1.1984631196118951 1.5348831490839385 1.616200091339425 0.8538077174015225 0.8852161951502759 0.7640355589782566 0.930636336235788 0.8119905589399623 1.0 12.36121917826519 -6.265891350577064 24.9915299806948 0.8658473344089433 1.5207291970242856 0.8130496137311274 0.15766862056253617 152.79367224687996 857719.5701692592 0.046318828117452866 0.05432977983369256 5.421365021885358e-07 6.265891350577064 0.6548818626153422 RVVLGDGVQLPPGDYS(ph)TTPGGTLFS(ph)TTPGGTR ddPTM_PC-9_AZD4547_30min_R2 3 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 RVVLGDGVQLPPGDY(0.098)S(0.354)T(0.159)T(0.384)PGGT(0.086)LFS(0.3)T(0.3)T(0.3)PGGT(0.018)R;RVVLGDGVQLPPGDY(0.004)S(0.332)T(0.332)T(0.332)PGGT(0.004)LFS(0.325)T(0.325)T(0.325)PGGT(0.022)R;RVVLGDGVQLPPGDY(0.101)S(0.446)T(0.119)T(0.335)PGGT(0.044)LFS(0.299)T(0.299)T(0.304)PGGT(0.053)R 83.02600000000001 6.0909e-08 18984200.0 30887.5 24359.1 43537.0 56974.0 51450.1 46805.2 40600.0 47985.0 36743.9 40638.6 True False 40709.08250008885 32232.70270683695 42959.67093342953 43839.5245395253 44307.14170837149 43878.463444894616 44213.32134737831 40570.020835603966 38686.10753984145 39215.85498342716 1.0380771378640792 0.8219303830162231 1.0954668960190852 1.117903066452386 1.1298272529591904 1.1188960042676082 1.1274348440461928 1.034531080675127 0.9864914983031841 1.0 15.259149433925048 -5.287390750828617 24.7065471540099 1.0842944490145607 0.9300037498045997 0.40834036556925835 0.06992355977552381 504.7856394351768 480571.5425093586 0.018084511386588557 0.037667301708568406 5.159519393039156e-06 5.287390750828617 -0.15429069920996108 RVVLGDGVQLPPGDYS(ph)TTPGGTLFS(ph)TTPGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 RVVLGDGVQLPPGDY(0.215)S(0.231)T(0.231)T(0.231)PGGT(0.108)LFS(0.3)T(0.3)T(0.3)PGGT(0.086)R;RVVLGDGVQLPPGDY(0.106)S(0.287)T(0.304)T(0.304)PGGT(0.062)LFS(0.397)T(0.397)T(0.133)PGGT(0.009)R 54.363 0.0012252 13374100.0 8981.7 9447.3 11444.8 16674.4 14049.1 11947.4 14554.2 11832.0 13930.6 11505.2 True False 10502.124413338826 10385.165508969409 11717.687436645707 15740.187427134195 11296.2797073082 11320.857311804339 13175.520812716899 11521.422537040271 14134.30867089404 13591.001684886909 0.7727262976515638 0.764120684387644 0.8621651080858659 1.1581329906416806 0.831158730549609 0.8329671038443801 0.969429709317745 0.8477243108469338 1.039975492506287 1.0 13.730364169176696 -5.522690189359596 24.999999999939103 0.9438362642553804 0.7796033053497489 0.37040980098452847 0.09668916045694285 7.168089057596106 950396.6407483168 0.026351648618345436 0.04627502564164021 3.0013027809480496e-06 5.522690189359596 -0.1642329589056315 RVVLGDGVQLPPGDYST(ph)TPGGT(ph)LFSTTPGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 RVVLGDGVQLPPGDY(0.029)S(0.275)T(0.675)T(0.166)PGGT(0.213)LFS(0.212)T(0.212)T(0.212)PGGT(0.005)R 77.488 9.7757e-07 12435000.0 25859.0 21218.0 28590.0 36404.0 44304.0 36887.0 35956.0 34005.0 35885.0 28220.0 True False 30236.417961469262 23324.382815123143 29271.694028178797 34364.4019033604 35622.94923892509 34952.58078414771 32549.98738110298 33112.40478127571 36409.750237249835 33336.06261060291 0.9070182737133518 0.6996741963072916 0.878078925219819 1.0308476530287778 1.0686009819166469 1.0484915747977581 0.9764196738324487 0.9932908144570122 1.0922030793663469 1.0 15.024796094323424 -5.642422040283752 3.739967118461804 1.030123189495776 0.8000448944927122 0.7287942914753034 0.05740152943187372 0.10483992617440584 2.7594157537586455 0.01540060985379365 0.028199786991163267 2.2781271492091337e-06 5.642422040283752 -0.23007829500306387 RVVLGDGVQLPPGDYST(ph)TPGGTLFS(ph)TTPGGTR ddPTM_PC-9_AZD4547_30min_R2 3 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 RVVLGDGVQLPPGDY(0.007)S(0.037)T(0.462)T(0.462)PGGT(0.065)LFS(0.318)T(0.318)T(0.318)PGGT(0.011)R;RVVLGDGVQLPPGDY(0.024)S(0.147)T(0.414)T(0.414)PGGT(0.107)LFS(0.297)T(0.297)T(0.297)PGGT(0.004)R;RVVLGDGVQLPPGDY(0.019)S(0.042)T(0.457)T(0.457)PGGT(0.032)LFS(0.323)T(0.323)T(0.323)PGGT(0.024)R 81.197 8.249700000000002e-07 63579000.0 85975.0 84312.0 107765.0 150622.0 120484.0 124091.0 98396.0 136291.0 99030.0 116229.0 True False 113313.26160890792 111564.20518897813 106335.96568759994 115898.42498670248 103756.87630522432 116331.57015332543 107153.05338169074 115230.35760561227 104264.52362624813 112159.85808735446 1.0102835679468778 0.9946892506059306 0.9480750733901727 1.033332485999013 0.9250803101446012 1.0371943415149643 0.9553601012782647 1.0273761002431583 0.9296064153811863 1.0 16.77519690349856 RVVLGDGVQLPPGDYST(ph)TPGGTLFS(ph)TTPGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 RVVLGDGVQLPPGDY(0.023)S(0.177)T(0.551)T(0.187)PGGT(0.077)LFS(0.321)T(0.321)T(0.321)PGGT(0.021)R;RVVLGDGVQLPPGDY(0.039)S(0.131)T(0.411)T(0.411)PGGT(0.098)LFS(0.286)T(0.286)T(0.293)PGGT(0.045)R;RVVLGDGVQLPPGDY(0.003)S(0.015)T(0.445)T(0.445)PGGT(0.134)LFS(0.314)T(0.314)T(0.314)PGGT(0.015)R;RVVLGDGVQLPPGDY(0.029)S(0.114)T(0.417)T(0.417)PGGT(0.033)LFS(0.27)T(0.27)T(0.27)PGGT(0.178)R;RVVLGDGVQLPPGDY(0.044)S(0.048)T(0.424)T(0.424)PGGT(0.08)LFS(0.309)T(0.309)T(0.309)PGGT(0.053)R 74.404 2.8392000000000003e-06 59369900.0 87125.2 83548.2 99196.0 111772.1 134046.3 123433.7 119153.0 119581.9 109443.6 89627.7 True False 101873.77555886151 91842.31314518215 101561.2088429251 105509.87160703768 107780.88977441605 116960.61947938999 107865.96524698427 116443.0018324962 111044.00560305065 105876.49251751708 0.9621944695797953 0.8674476360272986 0.9592422871972452 0.9965372775224988 1.017986969643747 1.1046892156919448 1.0187905046924182 1.099800333990389 1.0488069916433869 1.0 16.6920227814908 -5.930863577446316 1.496185617567258 1.057231067739325 0.9141857498769973 0.6610201470491386 0.038655746229940724 0.2140432001908047 0.9732014471381877 0.012492426156149646 0.02347456405925703 1.1725636387151101e-06 5.930863577446316 -0.14304531786232777 RVVLGDGVQLPPGDYST(ph)TPGGTLFS(ph)TTPGGTR ddPTM_PC-9_Lapatinib_30min_R1 5 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 RVVLGDGVQLPPGDY(0.015)S(0.08)T(0.412)T(0.412)PGGT(0.136)LFS(0.311)T(0.311)T(0.311)PGGT(0.012)R;RVVLGDGVQLPPGDY(0.007)S(0.069)T(0.673)T(0.251)PGGT(0.047)LFS(0.573)T(0.162)T(0.211)PGGT(0.007)R;RVVLGDGVQLPPGDY(0.06)S(0.107)T(0.403)T(0.403)PGGT(0.102)LFS(0.233)T(0.233)T(0.233)PGGT(0.227)R;RVVLGDGVQLPPGDY(0.017)S(0.138)T(0.423)T(0.423)PGGT(0.022)LFS(0.322)T(0.322)T(0.322)PGGT(0.01)R;RVVLGDGVQLPPGDY(0.077)S(0.197)T(0.36)T(0.36)PGGT(0.048)LFS(0.31)T(0.31)T(0.31)PGGT(0.029)R 97.81299999999999 2.5579e-12 47218100.0 80165.2 85640.2 92709.1 76128.6 96741.1 94360.9 99009.5 82662.0 101461.1 81780.6 True False 79022.0295475027 85441.90537861815 85086.91566547517 81727.35120156474 91050.9786983205 90325.30427300146 104135.72745279579 86502.77829246747 90033.48248525124 95916.26774420044 0.8238647249937512 0.8907968104689351 0.8870957728713328 0.8520697596316384 0.9492756634478814 0.941709955957528 1.0856941153143684 0.9018572169964135 0.938667491997937 1.0 16.549487901816057 -6.414585749344413 2.6449817931361608 0.974021217695997 0.8664595964036306 0.5318196562336 0.0489351672130073 0.24466662078990303 3.3370358756884753 0.016904775612010366 0.01931636215458673 3.8495879892190474e-07 6.414585749344413 -0.10756162129236646 RVVLGDGVQLPPGDYST(ph)TPGGTLFST(ph)TPGGTR ddPTM_PC-9_AZD4547_30min_R2 1 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 RVVLGDGVQLPPGDY(0.055)S(0.175)T(0.374)T(0.374)PGGT(0.026)LFS(0.104)T(0.36)T(0.36)PGGT(0.173)R 60.82899999999999 0.0010676 15866000.0 55188.0 56092.0 73121.0 83287.0 77547.0 77374.0 63744.0 80885.0 69501.0 64674.0 True False 72736.63601828902 74222.6420611557 72151.36776358732 64086.46892132284 66780.93760865545 72535.79154848772 69417.0925115095 68386.08180239316 73174.68097089628 62409.78294523354 1.1654684984582881 1.1892789649066444 1.1560906697416702 1.0268657556069478 1.070039574841299 1.1622503416193588 1.1122790247872691 1.0957590072441687 1.1724873492207024 1.0 15.929484573706242 -11.976238595604643 1.9888078945698058 1.90279352894311e-05 1.1254153291003737 0.3788586280909143 0.0490172991045294 1070370.2444172222 104891.66439793841 4804419.717885802 0.013519471468329157 1.0562370672064114e-12 11.976238595604643 1.1253963011650843 RVVLGDGVQLPPGDYST(ph)TPGGTLFSTT(ph)PGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 RVVLGDGVQLPPGDY(0.213)S(0.227)T(0.366)T(0.366)PGGT(0.116)LFS(0.216)T(0.216)T(0.23)PGGT(0.049)R 50.802 0.013356 5373000.0 4150.9 4136.6 3439.3 4912.7 4717.6 6634.3 4488.2 4316.0 3846.4 3524.2 True False 4853.565385987964 4547.2543101629935 3521.305955617886 4637.4573461882965 3793.2201455749614 6286.3856289823325 4063.045204245922 4202.709573180002 3902.6463233261165 4163.1095624481495 1.1658509854671675 1.0922735138128203 0.8458355233743006 1.1139407398783912 0.9111506888481523 1.5100216640192323 0.9759640344071598 1.0095121231228334 0.9374354109074022 1.0 12.02344581170151 RVVLGDGVQLPPGDYSTT(ph)PGGT(ph)LFSTTPGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 RVVLGDGVQLPPGDY(0.032)S(0.156)T(0.171)T(0.558)PGGT(0.559)LFS(0.158)T(0.158)T(0.158)PGGT(0.05)R 52.577 0.0078635 4128300.0 3510.5 3379.6 6326.2 3946.2 5960.3 3367.7 5295.5 4747.8 5188.8 3462.3 True False 4104.758314464517 3715.104353001702 6477.0406002471045 3725.1072077530157 4792.422001371551 3191.0918835029756 4793.871903900068 4623.175280709921 5264.676383754825 4089.987582448282 1.0036114368854374 0.9083412304097574 1.5836333166493195 0.9107869235933358 1.1717448781354953 0.780220433234855 1.1720993786075111 1.1303641362017218 1.2872108478635942 1.0 11.997880747690363 -10.691855470820943 3.8928263947661152 0.9999422171523896 1.1029772952183439 0.02096033934748054 0.2154286418655388 75041909.07495219 4.624020910706441 40316.95119160573 0.050731352903806634 2.0330334730699334e-11 10.691855470820943 0.10303507806595424 RVVLGDGVQLPPGDYSTT(ph)PGGTLFS(ph)TTPGGTR ddPTM_PC-9_AZD4547_30min_R2 2 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 RVVLGDGVQLPPGDY(0.006)S(0.158)T(0.136)T(0.652)PGGT(0.092)LFS(0.315)T(0.315)T(0.315)PGGT(0.01)R;RVVLGDGVQLPPGDY(0.021)S(0.07)T(0.211)T(0.648)PGGT(0.209)LFS(0.545)T(0.138)T(0.138)PGGT(0.021)R 77.469 1.9305e-06 37639000.0 50039.0 31635.0 60904.0 99318.0 70267.0 61984.0 52370.0 74738.0 44979.0 57592.0 True False 65950.36112414229 41860.3950938576 60096.373166033365 76421.76954780391 60511.63994670833 58108.13068138469 57030.82854586699 63188.95940838538 47356.49811355156 55575.721609640466 1.1866757500221496 0.7532137034203847 1.0813422016927752 1.3750927083697528 1.0888142914587304 1.045566823037075 1.0261824209219825 1.1369885550424286 0.8521076603589588 1.0 15.762167155251396 -8.257247224899945 24.990064664605455 0.9260538269835243 1.081728051220458 0.15539684603613402 0.1494762992793529 678.671751289145 4045730.595619626 0.11391537062217347 0.03949356244434062 5.530352007819707e-09 8.257247224899945 0.15567422423693356 RVVLGDGVQLPPGDYSTT(ph)PGGTLFS(ph)TTPGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 RVVLGDGVQLPPGDYS(0.035)T(0.163)T(0.783)PGGT(0.093)LFS(0.282)T(0.282)T(0.282)PGGT(0.079)R;RVVLGDGVQLPPGDY(0.157)S(0.173)T(0.173)T(0.389)PGGT(0.09)LFS(0.291)T(0.291)T(0.291)PGGT(0.144)R;RVVLGDGVQLPPGDY(0.074)S(0.2)T(0.206)T(0.491)PGGT(0.04)LFS(0.271)T(0.271)T(0.299)PGGT(0.147)R 108.75 4.0115999999999993e-08 11732000.0 17835.4 19437.8 18815.3 24937.8 28516.4 28581.9 24164.800000000003 21981.3 22646.9 21165.9 True False 20854.580954792877 21367.45632405506 19263.928109422606 23540.615915438462 22928.816126690228 27083.014848440704 21875.735205998382 21404.31416611252 22978.06806877452 25003.110120827805 0.8340794746738659 0.8545919375948269 0.7704612752705348 0.9415075085330655 0.9170385610384657 1.0831858403839256 0.8749205638931977 0.8560660678881921 0.9190083936651381 1.0 14.609819941509551 -5.777337954411767 24.969365066569793 0.9377663516291472 0.8231990060953085 0.43537939311414353 0.06350201520846203 236.32823565975295 371162.59501711436 0.0187594393626825 0.02792794347917185 1.6697907295787704e-06 5.777337954411767 -0.11456734553383874 RVVLGDGVQLPPGDYSTT(ph)PGGTLFS(ph)TTPGGTR ddPTM_PC-9_Lapatinib_30min_R1 1 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 RVVLGDGVQLPPGDYS(0.001)T(0.056)T(0.934)PGGT(0.122)LFS(0.295)T(0.295)T(0.295)PGGT(0.002)R 107.94 3.9305e-15 18442000.0 79705.0 54377.0 68175.0 70296.0 79279.0 79316.0 68667.0 61406.0 77685.0 62652.0 True False 78568.39208389322 54251.09339741289 62569.9146631104 75465.80234058155 74615.96508851094 75923.83957462655 72222.24126978856 64259.14693362426 68935.2972406838 73481.31472145747 1.0692295365389028 0.738297805408902 0.851507827538083 1.0270066972351624 1.0154413454815627 1.0332400809978408 0.982865392971783 0.8744964237127316 0.9381336942866895 1.0 16.165089818807076 -5.7525907585892595 24.95606252151689 0.9799830909359135 0.8715403071529866 0.19302977247604847 0.08765187871497455 278.5654682699852 785639.5355896985 0.024077200091073062 0.04091715349538207 1.7677027657131213e-06 5.7525907585892595 -0.10844278378292693 RVVLGDGVQLPPGDYSTT(ph)PGGTLFSTT(ph)PGGTR ddPTM_PC-9_AZD4547_30min_R2 2 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 RVVLGDGVQLPPGDY(0.001)S(0.003)T(0.078)T(0.896)PGGT(0.046)LFS(0.28)T(0.28)T(0.403)PGGT(0.013)R;RVVLGDGVQLPPGDY(0.003)S(0.08)T(0.08)T(0.837)PGGT(0.044)LFS(0.231)T(0.231)T(0.475)PGGT(0.021)R 94.037 2.1197e-12 32895000.0 61883.0 42464.0 89886.0 107591.0 97496.0 78856.0 62795.0 91006.0 74337.0 83764.0 True False 81560.50675363826 56189.65757122075 88694.05290953102 82787.55721437959 83960.36330346059 73925.12185420889 68383.63334996607 76943.11380983597 78266.30205800677 80831.44785577728 1.0090194957185696 0.6951459990111348 1.0972716097796802 1.024199855507877 1.0387091352522355 0.9145589224890425 0.8460028264244245 0.9518957763458717 0.968265497330354 1.0 16.302629069046205 -5.4061422485221575 0.005545480068778252 1.883437198619607 8.66340279758976e-05 0.01112425658312377 0.10811492821831865 131393.19447965428 141.16009874376687 23201.177558195628 24752.659817576157 3.925163498014279e-06 5.4061422485221575 -1.883350564591631 RVVLGDGVQLPPGDYSTT(ph)PGGTLFSTT(ph)PGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 RVVLGDGVQLPPGDY(0.01)S(0.08)T(0.08)T(0.811)PGGT(0.032)LFS(0.165)T(0.165)T(0.616)PGGT(0.039)R 77.233 1.0159999999999999e-06 14690000.0 47596.0 52470.0 54265.0 66337.0 70682.0 67562.0 66718.0 59091.0 58084.0 55260.0 True False 55653.06273614958 57678.874837850446 55558.88340115855 62620.35295745581 56832.36949498253 64018.92978389649 60397.98804350949 57539.923862089774 58933.36861586789 65278.200562080696 0.8525520350889966 0.8835855513970065 0.851109297173734 0.9592843003983049 0.8706178939619201 0.9807091683388758 0.9252397817870295 0.881456954490777 0.9028032039550667 1.0 15.994313668538652 -5.749597155117956 24.996626484146457 0.9257649059031535 0.8645326068034556 0.38094939207192546 0.03983957054046305 255.6069445355082 539531.8094288046 0.01049351373714242 0.017992559665578074 1.7799296799342234e-06 5.749597155117956 -0.06123229909969796 RVVLGDGVQLPPGDYSTT(ph)PGGTLFSTT(ph)PGGTR ddPTM_PC-9_Lapatinib_30min_R1 1 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 RVVLGDGVQLPPGDY(0.003)S(0.022)T(0.247)T(0.681)PGGT(0.052)LFS(0.094)T(0.314)T(0.579)PGGT(0.008)R 89.95299999999999 2.8181e-09 17824000.0 76353.0 78654.0 97466.0 81062.0 102440.0 90699.0 81554.0 87044.0 106350.0 83106.0 True False 75264.19221857456 78471.88149548751 89452.7217096402 87023.56989490477 96414.68060478891 86820.01519969554 85776.46707321332 91088.382009745 94371.74308485199 97470.76136821565 0.7721719945763915 0.8050812407122173 0.9177390271090048 0.8928171758724189 0.9891651532356747 0.8907288091422129 0.8800225408025207 0.9345200625410125 0.968205662499583 1.0 16.57268189322967 -5.195621768421351 1.9309944943633381 0.9322860451950131 0.7635217641677876 0.6942319317672557 0.038998760741051235 0.2361376069846986 1.5163859259905468 0.010995535462126263 0.05218821218985547 6.373503543163935e-06 5.195621768421351 -0.16876428102722552 RVVLGDGVQLPPGDYSTTPGGT(ph)LFSTTPGGTR ddPTM_PC-9_AZD4547_30min_R2 1 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 RVVLGDGVQLPPGDY(0.038)S(0.06)T(0.074)T(0.029)PGGT(0.208)LFS(0.174)T(0.174)T(0.174)PGGT(0.07)R 50.879 0.038845 0.0 11287.0 6290.6 10315.0 13105.0 14061.0 10285.0 5043.4 11227.0 9553.5 10172.0 True False 14876.031215815541 8323.913430612312 10178.216360298735 10083.844720231675 12108.872860527219 9641.87732411657 5492.252829639597 9492.125120794542 10058.478506143198 9815.88137611584 1.515506417183498 0.8480046886942004 1.0369131380361354 1.02729895908969 1.2336001624867556 0.9822732116116788 0.5595272211625779 0.9670170978116069 1.0247147577208553 1.0 13.260902098951872 -6.998557564599958 24.964702622001347 0.8687567713577174 1.1056030430659995 0.24048363645059245 0.20209811194864455 70.45810780532977 1219413.59368361 0.0705829866947297 0.061788071677904254 1.0033268519785272e-07 6.998557564599958 0.2368462717082821 RVVLGDGVQLPPGDYSTTPGGT(ph)LFSTTPGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 RVVLGDGVQLPPGDY(0.003)S(0.003)T(0.004)T(0.039)PGGT(0.459)LFS(0.151)T(0.151)T(0.151)PGGT(0.039)R 68.834 0.0010027 0.0 10897.0 7484.5 9508.9 10822.0 7377.0 7303.2 5644.9 7777.8 8342.4 6083.1 True False 12741.646874439492 8227.511696662701 9735.628238704061 10215.67842539739 5931.529806237593 6920.2073354511795 5110.174206463124 7573.640991260293 8464.391817729778 7185.917876206898 1.7731411761089033 1.1449493075762245 1.3548204149311867 1.4216247111899583 0.8254380175812089 0.9630234375993211 0.7111372958189915 1.053955962443876 1.1779137980070717 1.0 12.810956732350332 -6.253688050171426 24.616202796508187 0.9461261094542073 1.3988126452696945 0.6025518738212975 0.1858360220947688 348.56046661746313 1106935.9168314468 0.055151767750945845 0.06982897557324586 5.575861142268517e-07 6.253688050171426 0.45268653581548723 RVVLGDGVQLPPGDYSTTPGGT(ph)LFSTTPGGTR ddPTM_PC-9_Lapatinib_30min_R1 1 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 RVVLGDGVQLPPGDY(0.006)S(0.005)T(0.078)T(0.288)PGGT(0.298)LFS(0.056)T(0.124)T(0.122)PGGT(0.023)R 58.498000000000005 0.00082284 5669900.0 23772.0 15160.0 21472.0 13734.0 11513.0 8401.6 10599.0 9973.7 9601.7 8653.1 True False 23433.006920749103 15124.897951427623 19706.655044316907 14744.044175280935 10835.82797542889 8042.283153086175 11147.764358694702 10437.114512781944 8520.255435616575 10148.77680546901 2.3089488881183633 1.490317329993607 1.9417763758187403 1.4527902680188622 1.0676979288370634 0.7924386659831084 1.0984342815271446 1.028411079762593 0.8395352069448555 1.0 13.30901823474061 -6.0568989605687085 2.0007294692242596 0.9571992716568437 1.889832363829883 0.8111388221113852 0.204640359748515 0.1352690736942461 1.0778413667040687 0.06387933129762666 0.0970604293478214 8.772048807772205e-07 6.0568989605687085 0.9326330921730394 RVYEILR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RVYEILR 7 1 O14929-2;O14929 O14929-2 HAT1 Histone acetyltransferase type B catalytic subunit 0 103.74 0.0066184 1307400.0 8475.6 9473.2 10410.0 10802.0 14923.0 8352.1 10262.0 9479.4 9681.7 7108.9 False True 9910.351679269468 10413.636689802264 10658.213880144853 10196.798960556513 11998.945275651837 7914.101172968255 9289.909069553869 9230.575794254524 9823.276546523111 8397.68729597856 1.1801286866224807 1.2400600692513393 1.26918442000678 1.2142389447436919 1.4288392568984831 0.9424143688653563 1.1062461296936565 1.0991806992711926 1.1697597445938752 1.0 13.035776352313421 -6.768220178049408 24.99999857208049 1.0723893749975197 1.2622687561953887 0.5914158677841582 0.08415434097236846 122.09943404163317 450163.4230380624 0.029057552316611453 0.026200176406023262 1.705217660798968e-07 6.768220178049408 0.18987938119786896 RWDDSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RWDDSQK 7 1 Q16543;K7EKQ2 Q16543 CDC37 Hsp90 co-chaperone Cdc37;Hsp90 co-chaperone Cdc37, N-terminally processed 0 ; 123.98 0.002947 5495700.0 47652.0 57141.0 57129.0 59501.0 72742.0 69171.0 59947.0 67352.0 62461.0 49641.0 False True 55718.54243009917 62813.58084828687 58491.17202293899 56167.35187484477 58488.72728281626 65543.55099141391 54268.386181304355 65584.08136534297 63374.3739603974 58640.520342060205 0.9501713508864411 1.071163429005822 0.9974531549472951 0.9578249228896841 0.9974114646602978 1.1177177591380012 0.9254417570776582 1.1184089258209133 1.0807266646121798 1.0 15.839610284719319 -6.605754561875686 24.999999974418937 1.049215248043255 0.9970913055656047 0.16066906724097596 0.06119272947030535 53.66804081580514 16183.742035427556 0.019794969132561666 0.01979497265602131 2.4788225490028606e-07 6.605754561875686 -0.0521239424776504 RWDDSQK ddPTM_PC-9_Lapatinib_30min_R1 2 RWDDSQK 7 1 Q16543;K7EKQ2 Q16543 CDC37 Hsp90 co-chaperone Cdc37;Hsp90 co-chaperone Cdc37, N-terminally processed 0 ; 103.83 0.0066056 7109300.0 57874.0 58484.0 52173.0 50640.0 63244.0 49665.0 56195.0 55254.0 58454.0 46060.0 False True 57048.70614720821 58348.58389124626 47883.53733360406 54364.234530087844 59524.11226248806 47540.94372476964 59104.502135753275 57821.30255464406 51870.29497209151 54021.40962890788 1.0560388286624858 1.0801010986581665 0.8863807453847089 1.0063460932162813 1.1018615151174356 0.8800389336625082 1.0940940368228624 1.070340499291651 0.9601803308800505 1.0 15.721243665418202 RWDQTADQTPGAT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 RWDQTADQTPGATPK 15 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 RWDQTADQTPGAT(1)PK;RWDQTADQT(0.006)PGAT(0.993)PK 128.82 5.7568e-05 89533100.0 100725.0 101963.0 106375.0 135925.0 125078.0 106981.0 103655.0 122355.0 88157.0 111612.0 True False 132753.45478984853 134920.54575486013 104964.39799580976 104589.59127031593 107713.07870343681 100291.46115812483 112880.09419365734 103447.84618819041 92816.79904391752 107704.49785204901 1.2325711315437229 1.2526918415254775 0.9745590953870538 0.9710791411328805 1.0000796703160864 0.9311724501598133 1.0480536694829394 0.9604784224545027 0.861772729040691 1.0 16.716718974025056 -5.263443633302344 23.666096666303066 0.9697303021528483 1.2426315306493863 0.8488291692441067 0.046288865648768926 26.678405920633473 315028.82910750195 0.011980302071178499 0.02715022142387877 5.452006522087522e-06 5.263443633302344 0.272901228496538 RWDQTADQTPGAT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 RWDQTADQTPGATPK 15 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 RWDQTADQT(0.002)PGAT(0.998)PK;RWDQTADQT(0.001)PGAT(0.999)PK;RWDQTADQT(0.044)PGAT(0.956)PK;RWDQTADQT(0.004)PGAT(0.996)PK 164.82 0.00022389 92021700.0 314488.0 282339.0 238552.0 258247.0 244153.0 239105.0 229618.0 239036.0 248495.0 214316.0 True False 310003.3434499642 281685.2613923565 218939.17539734978 277239.345866738 229792.4005632668 228879.0365309783 241506.49651049695 250142.48520382008 220506.87633164352 251360.23504188086 1.2333030457196716 1.1206436903013834 0.8710175472300573 1.1029562644248214 0.9141955191320517 0.9105618336680947 0.9607983397622853 0.9951553600438913 0.8772544165345141 1.0 17.939396909217194 -5.04638987559028 4.033222495764875 0.9568005355097343 1.217247620400391 0.662660688635496 0.06575982798854295 0.11454940867845186 3.8776999399997876 0.016308263954951985 0.05689872516492367 8.986904453579822e-06 5.04638987559028 0.2604470848906567 RWS(ph)APAAAGQR ddPTM_PC-9_AZD4547_30min_R2 1 RWSAPAAAGQR 11 1 C9JI98 C9JI98 TMEM238 Transmembrane protein 238 1 RWS(1)APAAAGQR 73.877 0.010839 9234500.0 9168.4 14938.0 11484.0 11401.0 13937.0 8307.8 10386.0 11356.0 9793.1 4716.5 True False 12083.760485433091 19766.416371488693 11331.714656487695 8772.675593694104 12002.08812013142 7788.311952678236 11310.333879651987 9601.191134919634 10310.743272990108 4551.376770590873 2.6549681765555837 4.342953213456455 2.4897333768780867 1.927477340566382 2.6370236359433004 1.7111991261640012 2.485035726493732 2.10951358651707 2.2654119385619524 1.0 12.15208730462316 -1.5228787452803376 0.12071026046289712 0.8081849671745968 9.043841779221053 0.48143709283394365 0.5875686595408468 81.98060172477406 0.6821246159662416 4.053000720805809 113.57773301851992 0.029999999999999995 1.5228787452803376 8.235656812046455 RWS(ph)APESR ddPTM_PC-9_AZD4547_30min_R2 1 RWSAPESR 8 1 P54253 P54253 ATXN1 Ataxin-1 1 RWS(1)APESR 71.221 0.016503999999999998 10438000.0 18310.0 16322.0 29439.0 38874.0 35139.0 27092.0 27484.0 30982.0 21867.0 20575.0 True False 24132.19912834079 21597.76730589359 29048.619624899104 29912.199897312934 30260.55639329107 25397.93295721597 29930.02275643705 26194.44379553367 23022.844977634726 19854.675512542584 1.2154416279982019 1.0877925097415901 1.463061917408246 1.5065569758829258 1.5241022888626354 1.2791915406107546 1.5074546414787626 1.3193085819501875 1.1595679296340424 1.0 14.277191162458115 -8.425938623890616 2.327690180777501 1.0048189471254587 1.3716458925669286 0.43598682018533874 0.13535512382815165 0.28387778166942895 3.2078053420094483 0.14083917324822356 0.03895311081491844 3.7502599856774105e-09 8.425938623890616 0.3668269454414699 RWS(ph)APESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RWSAPESR 8 1 P54253 P54253 ATXN1 Ataxin-1 1 RWS(1)APESR;RWS(1)APESR 73.666 0.013444999999999999 14282500.0 59870.0 58897.0 69618.0 76379.0 80102.0 69961.0 73772.0 54772.0 64587.0 75530.0 True False 70004.80851359932 64743.904923287206 71277.95714773508 72099.73225405907 64406.588117018364 66292.12200069838 66783.78209697203 53334.293035731054 65531.46268840057 89222.99110484899 0.7846050400992977 0.725641498021563 0.79887432897171 0.8080846804309912 0.7218608939183846 0.7429937192174632 0.74850418339475 0.597764010994163 0.7344683458481268 1.0 16.44512789327178 -10.534112632994804 5.049346935701716 1.000002652882489 0.7391798064000024 0.6620225558424939 0.05565978355915779 83860981.9934729 14.608812383109175 2586.560878347577 0.014385588724821447 2.923394105868366e-11 10.534112632994804 -0.26082284648248666 RWS(ph)APESR ddPTM_PC-9_Lapatinib_30min_R1 4 RWSAPESR 8 1 P54253 P54253 ATXN1 Ataxin-1 1 RWS(1)APESR;RWS(1)APESR;RWS(1)APESR;RWS(1)APESR 74.944 0.012409 25725100.0 79406.0 68923.0 90838.0 79296.0 84737.0 84857.0 75345.0 86570.0 100796.0 74394.0 True False 78273.65587872318 68763.41302811645 83369.65028482015 85127.69236370148 79752.93625935183 81227.86392132854 79245.99543408355 90592.35823932254 89443.29305106465 87252.90377622614 0.8970894089607416 0.7880931184189708 0.9554942778596205 0.9756430866991533 0.9140433476448054 0.9309474000962791 0.9082333309768398 1.0382732759434683 1.0251039126497854 1.0 16.412915524554847 -4.722672893447981 0.2574149379953284 1.0243863410906975 0.7024966314383573 0.4733647777952976 0.05058279280014567 9.06088125425349 0.4979480413265662 0.07503805386403108 0.936843655455183 1.8937694510983647e-05 4.722672893447981 -0.3218897096523402 RWS(ph)EPSSQK ddPTM_PC-9_AZD4547_30min_R2 2 RWSEPSSQK 9 1 Q9BQK8;Q9BQK8-2 Q9BQK8 LPIN3 Phosphatidate phosphatase LPIN3 1 RWS(1)EPSSQK;RWS(1)EPSSQK 128.51 0.0019504000000000001 19800800.0 71096.0 59900.0 72030.0 82789.0 75590.0 67494.0 60011.0 75720.0 65960.0 63979.0 True False 93703.04911133346 79261.50359165696 71074.83513643405 63703.27512729955 65095.633278376445 63273.58951034751 65351.8627432886 64019.213872500426 69446.51093999104 61739.114683691994 1.5177258305598045 1.2838134138744526 1.1512124121081384 1.031813874456583 1.0543661601220053 1.0248541760683982 1.0585163567392535 1.036931193466088 1.124838140225793 1.0 15.913897174931954 -4.814699737795679 1.2016604235085688 1.0466688060046514 1.7192803985782514 0.9511119496642816 0.0336437581550679 0.2713388321645361 0.34651536394249227 0.010066165059914055 0.22637961749609406 1.5321463898405696e-05 4.814699737795679 0.6726115925736 RWS(ph)EPSSQK ddPTM_PC-9_Lapatinib_30min_R1 1 RWSEPSSQK 9 1 Q9BQK8;Q9BQK8-2 Q9BQK8 LPIN3 Phosphatidate phosphatase LPIN3 1 RWS(0.992)EPS(0.005)S(0.003)QK 122.55 0.0022765999999999997 10800000.0 41018.0 34111.0 38380.0 32434.0 29150.0 27454.0 26263.0 23321.0 34484.0 31365.0 True False 40433.075798220045 34032.0180752736 35224.54455108434 34819.30455665222 27435.45431110501 26279.856418399806 27622.76963415408 24404.57879749617 30600.04878738163 36786.39845876456 1.0991311324902653 0.9251250326509004 0.9575426251789512 0.946526597206374 0.7458043043234738 0.7143905769372344 0.75089627665284 0.6634131042986527 0.8318305153379592 1.0 15.166884816936092 -6.189322544015725 4.028982346102147 0.7619818949707678 0.9819636108388639 0.4994364076350153 0.0958382471241081 0.17495549912799999 5.5160026633719434 0.027748923097133008 0.036047769882473324 6.466621710391732e-07 6.189322544015725 0.219981715868096 RWS(ph)GNEPTDEFSDLPLR ddPTM_PC-9_AZD4547_30min_R2 2 RWSGNEPTDEFSDLPLR 17 1 E9PD99;Q96II8-3;Q96II8-4;Q96II8;Q96II8-2 E9PD99 LRCH3 Leucine-rich repeat and calponin homology domain-containing protein 3 1 RWS(1)GNEPTDEFSDLPLR;RWS(1)GNEPTDEFSDLPLR 128.82 1.4434000000000001e-05 4649900.0 8165.4 14027.7 18031.5 20964.6 17780.7 19878.0 17378.9 17472.300000000003 15926.8 15664.699999999999 True False 10761.827349129111 18561.879698375426 17792.390528427204 16131.535369841196 15312.156722222904 18635.02551762657 18925.588432609657 14772.357508511483 16768.658132793378 15116.28362096359 0.7119360564394529 1.227939364185613 1.1770347113461361 1.0671627877813588 1.0129577551050757 1.2327782400022658 1.2520000885907725 0.9772479717187138 1.1093108963328948 1.0 13.883815872241108 -4.7521997035813355 24.999952419963314 1.121514906859445 0.7119352593287535 0.6105285111376431 0.09709848015628827 254.70410338495364 689107.8941098667 0.024712973600453287 0.30226691523760363 1.7692951882824932e-05 4.7521997035813355 -0.40957964753069154 RWS(ph)GNEPTDEFSDLPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RWSGNEPTDEFSDLPLR 17 1 E9PD99;Q96II8-3;Q96II8-4;Q96II8;Q96II8-2 E9PD99 LRCH3 Leucine-rich repeat and calponin homology domain-containing protein 3 1 RWS(1)GNEPTDEFSDLPLR 134.04 1.2207e-05 2163000.0 4989.9 3770.5 5650.1 5419.7 6019.5 4594.6 5258.0 3907.1 3894.0 4022.9 True False 5834.591514982622 4144.810321633601 5784.819812123577 5116.05177990447 4840.022186342306 4353.651087668964 4759.924175376557 3804.54276491464 3950.9423832757657 4752.219924741123 1.227761258397666 0.8721840292059695 1.2172878999152603 1.076560399334458 1.0184760518224472 0.9161299680182896 1.0016211898349494 0.8005822173985124 0.8313887921529628 1.0 12.214385887844449 -6.758390493968964 1.3161029646937794 0.8843130492860347 1.092737190045009 0.3981376354569117 0.10881060965957029 0.43727189882068873 1.5883426398030933 0.05070703502380915 0.04588297657153503 1.744253110132231e-07 6.758390493968964 0.2084241407589742 RWS(ph)GNEPTDEFSDLPLR ddPTM_PC-9_Lapatinib_30min_R1 2 RWSGNEPTDEFSDLPLR 17 1 E9PD99;Q96II8-3;Q96II8-4;Q96II8;Q96II8-2 E9PD99 LRCH3 Leucine-rich repeat and calponin homology domain-containing protein 3 1 RWS(1)GNEPTDEFSDLPLR;RWS(1)GNEPTDEFSDLPLR 134.83 1.5724e-05 5187700.0 11600.5 14690.9 15686.900000000001 12737.4 15679.0 16376.0 13033.3 11909.0 18841.6 13918.2 True False 11435.074742728839 14656.884123656202 14397.18363518513 13674.15088672079 14756.792046100021 15675.636654320504 13708.100501573323 12462.33561594194 16719.460597156052 16323.942325164242 0.7005093815542984 0.8978764952545698 0.8819673182127759 0.8376745405208487 0.9039968257760643 0.9602849815363327 0.8397542841376953 0.7634390864473084 1.0242293352986243 1.0 13.994701898018054 -1.5228787453770907 0.02955894018259762 1.4877883644779837 3.035382305647084e-09 0.3206944256267319 0.07894789625012896 2044.6512951048396 4.652914628807339 75.23142127852321 179.73524451267673 0.029999999993316533 1.5228787453770907 -1.4877883614426013 RWS(ph)WGGSAMANSESK ddPTM_PC-9_Lapatinib_30min_R1 2 RWSWGGSAMANSESK 15 1 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1;Q8IWC1-3 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 1 RWS(0.995)WGGS(0.004)AMANSESK;RWS(0.998)WGGS(0.002)AMANSESK 85.469 0.01078 3278800.0 73543.0 53015.0 55014.0 56343.0 59222.0 49438.0 37253.0 48660.0 61502.0 37541.0 True False 72494.2633338654 52892.24702473186 50490.9612801812 60486.65217473815 55738.67839493181 47323.65198560681 39181.778059671065 50920.92124206355 54574.997115228616 44029.91182976183 1.6464775949168085 1.20127987603599 1.1467422754649272 1.373762736764157 1.2659275496721638 1.07480687602964 0.8898899959455814 1.1565074542721152 1.239498214900782 1.0 15.426196334819197 -6.702410192018153 4.173718344258113 1.0694449050046517 1.3176295238473084 0.4185780854437875 0.15097141718796392 0.24307846732812047 8.540322344315566 0.053462061691780256 0.05202419101270185 1.984219932286561e-07 6.702410192018153 0.24818461884265663 RWY(ph)T(ph)ERLR ddPTM_PC-9_AZD4547_30min_R2 1 RWYTERLR 8 2 Q9Y2L6 Q9Y2L6 FRMD4B FERM domain-containing protein 4B 2 RWY(1)T(1)ERLR 75.043 0.024373 28972000.0 4695.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 6188.044135853246 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RY(ph)LS(ph)TY(ph)TATSSTSRALIL ddPTM_PC-9_AZD4547_30min_R2 1 RYLSTYTATSSTSRALIL 18 2 E7EWZ1;P10243-2;P10243 E7EWZ1 MYBL1 Myb-related protein A 3 RY(0.962)LS(0.474)T(0.519)Y(0.509)T(0.379)AT(0.083)S(0.039)S(0.019)T(0.017)S(0.001)RALIL 54.412 0.043085000000000005 0.0 5962.6 2256.3 8096.9 18265.0 12725.0 6607.2 6534.4 7272.0 2562.5 5613.2 True False 7858.582770215448 2985.6048506486777 7989.52981557952 14054.28644143697 10958.353399488578 6194.05073951415 7115.948941189863 6148.279493935861 2697.9485185525664 5416.683576525107 1.4508107514851107 0.5511868671058672 1.4749855151599858 2.594629396914676 2.023074311924003 1.1435134897593071 1.3137095495164337 1.1350634400320805 0.4980812485050761 1.0 12.403194100796616 -7.6920775222477555 1.5005575320623366 0.7780727122173077 1.5664597111855139 0.265411544981466 0.5138569703363532 0.6519309533817428 2.775600637584087 0.44370756323451227 0.18260512191836212 2.0319942643911655e-08 7.6920775222477555 0.7883869989682062 RY(ph)MTTIRAPS(ph)PRR ddPTM_PC-9_AZD4547_30min_R2 1 RYMTTIRAPSPRR 13 3 P31629 P31629 HIVEP2 Transcription factor HIVEP2 2 RY(0.835)MT(0.159)T(0.007)IRAPS(1)PRR 61.235 0.035962 0.0 8229.3 9146.2 12596.0 12359.0 12302.0 12777.0 8242.4 12652.0 10274.0 12530.0 True False 10846.046219926546 12102.530286310743 12428.968809919805 9509.82349464656 10594.079647977085 11978.052170173793 8975.957632355441 10696.924114036925 10817.062665213296 12091.328513835182 0.8970103001929229 1.000926430248152 1.0279241686054834 0.7864994722263312 0.8761716825289372 0.9906316048288841 0.7423466844098181 0.884677320759026 0.8946132472404632 1.0 13.561685146470989 -5.74737402648852 24.999463479521193 0.8757769602566566 0.9778509064826372 0.2176696963065048 0.08025352831687028 331.48441118461903 589168.6590684111 0.0213146583404581 0.03668866713716985 1.789064398332326e-06 5.74737402648852 0.10207394622598054 RY(ph)PHT(ph)S(ph)ATFLTSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RYPHTSATFLTSSK 14 1 H0YCE4;O95561 H0YCE4 C1orf105 Uncharacterized protein C1orf105 3 RY(0.999)PHT(0.994)S(0.938)AT(0.068)FLTSSK 60.448 0.033645999999999995 0.0 5221.4 4880.9 5776.7 7025.9 8986.6 5693.6 7455.7 10711.0 6147.6 7010.5 True False 6105.2798926492 5365.443495255658 5914.438436256751 6632.261601275131 7225.740240847873 5395.017592990036 6749.442121406425 10429.847599242594 6237.497019883433 8281.44815491253 0.7372237051351418 0.6478871080141814 0.7141792504911504 0.8008577095711085 0.8725213399496543 0.651458234365656 0.815007471537774 1.2594231593487233 0.7531891648906077 1.0 13.015667354709109 -7.539786224309086 24.90582553232405 1.011226885376645 0.7405955282251928 0.46070941710152336 0.1290722069687847 193.50478295590264 285041.6355646907 0.057181997612954415 0.033024029990647435 2.8854514787850166e-08 7.539786224309086 -0.27063135715145226 RY(ph)SDFVTLQER ddPTM_PC-9_AZD4547_30min_R2 1 RYSDFVTLQER 11 1 Q7Z614-2 Q7Z614-2 1 RY(0.804)S(0.195)DFVT(0.001)LQER 63.076 0.046336 0.0 8163.0 12017.0 14626.0 18266.0 16645.0 11965.0 13722.0 18459.0 13711.0 13846.0 True False 10758.664199052211 15901.260244756968 14432.049683541363 14055.05590688682 14334.129063613926 11216.826658537175 14943.231416963674 15606.585695621838 14435.735468438726 13361.255754394408 0.8052135515416486 1.1901022281926736 1.0801417133860924 1.0519262684021469 1.072813014517707 0.8395039257330325 1.1184002231264054 1.1680478229367743 1.0804175695604756 1.0 13.70576798507848 RYASGSSASLGGPES(ph)AVA ddPTM_PC-9_AZD4547_30min_R2 1 RYASGSSASLGGPESAVA 18 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 RYAS(0.012)GS(0.014)S(0.014)AS(0.059)LGGPES(0.9)AVA 59.88399999999999 0.040645999999999995 10094000.0 17567.0 14249.0 25424.0 30026.0 21940.0 20635.0 22795.0 23465.0 16802.0 18380.0 True False 23152.940583700856 18854.71059561806 25086.861148253513 23103.969597075615 18894.009711966937 19344.69018795775 24823.710840233703 19839.02342205787 17690.119418037168 17736.521794436594 1.3053822419096412 1.063044424050053 1.4144183081105843 1.3026212165410371 1.0652601412467133 1.0906698851195045 1.3995816726603152 1.1185408081690948 0.9973837950339293 1.0 14.114435498438162 -7.998484502544091 24.98610004796551 1.0184486536138568 1.2277525131135714 0.37372336817499274 0.12211033131609468 52.9689137851198 873308.9168816734 0.06891856683337383 0.032719589085804454 1.0034956574596729e-08 7.998484502544091 0.20930385949971453 RYASGSSASLGGPES(ph)AVA ddPTM_PC-9_Lapatinib_30min_R1 1 RYASGSSASLGGPESAVA 18 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 RYASGSSASLGGPES(1)AVA 84.821 0.0028012 7065800.0 28564.0 22421.0 28068.0 20431.0 23231.0 22474.0 20665.0 22808.0 21855.0 16890.0 True False 28156.672122003947 22369.085552042125 25760.35738561323 21933.563895818017 21864.598253903296 21512.8394094528 21734.93258537843 23867.742944697602 19393.45975664728 19809.41399548965 1.4213783471037993 1.1292149054553193 1.3004098653033622 1.107229315355417 1.1037478574016164 1.0859907019132924 1.097202198425819 1.2048687028365395 0.9790021936571633 1.0 14.27389858242674 -1.5228787452803376 0.3903110112815056 1.0667111242461467 5.636834826025418 0.5982846110242529 0.08062158001799485 51.54715014324912 0.693876563475376 0.0573379244210129 179.73403658933344 0.029999999999999995 1.5228787452803376 4.570123701779272 RYDDPEVQK ddPTM_PC-9_AZD4547_30min_R2 3 RYDDPEVQK 9 1 P38646;D6RJI2;A0A3B3ITI4 P38646 HSPA9 Stress-70 protein, mitochondrial 0 ;; 136.96 0.00061515 12532800.0 99302.0 98927.0 113604.0 131359.0 126158.0 125881.0 103279.0 133884.0 113499.0 118486.0 False True 130877.9703900872 130903.21812707603 112097.53673246504 101076.21202631909 108643.1393455936 118009.64117035666 112470.63092206583 113195.30414825476 119498.32542719916 114337.84120433159 1.1446601493568256 1.1448809663385255 0.9804062727766311 0.8840136472901143 0.9501940757429462 1.0321136023502773 0.9836693586078042 0.9900073585084135 1.0451336510162488 1.0 16.802943430769105 -5.261713374172306 11.568212254243612 0.9798677322262347 1.1448216810458367 0.703352989616842 0.041929217446789915 0.0415965000511719 365.097537810861 0.011818135471778506 0.027447247244123903 5.473771018442556e-06 5.261713374172306 0.16495394881960201 RYDDPEVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RYDDPEVQK 9 1 P38646;D6RJI2;A0A3B3ITI4 P38646 HSPA9 Stress-70 protein, mitochondrial 0 ;; 128.35 0.0008435000000000001 19910600.0 99604.0 120209.0 114492.0 113424.0 131232.0 104092.0 110963.0 117823.0 98267.0 100838.0 False True 116464.98993132697 132142.55508639553 117221.92349332798 107069.22100556955 105518.03165679445 98633.23227650668 100451.78133744947 114730.2710937877 99703.96897210053 119119.13116683143 0.9777185981000213 1.1093310855443046 0.9840730229064018 0.8988415207261252 0.885819352636244 0.828021756961664 0.8432883983745857 0.9631557078191164 0.8370105456231112 1.0 16.862045610753924 -5.644424384754417 3.1499351638370565 0.8861152667456139 1.044865994853004 0.5110443241421134 0.059651651866871304 0.1739282766036353 3.40947860088782 0.016125894519573844 0.030541671995741648 2.2676478641638857e-06 5.644424384754417 0.15875072810739 RYDDPEVQK ddPTM_PC-9_Lapatinib_30min_R1 2 RYDDPEVQK 9 1 P38646;D6RJI2;A0A3B3ITI4 P38646 HSPA9 Stress-70 protein, mitochondrial 0 ; 148.56 0.00020225 11492000.0 111928.0 129883.0 110105.0 101844.0 86681.0 97467.0 88012.0 67828.0 123617.0 84868.0 False True 110331.88619491852 129582.26389348788 101052.59191759118 109333.94750162461 81582.59400140282 93298.56361667426 92568.8307139767 70979.5364982879 109693.951715281 99537.32072049846 1.1084474184786557 1.3018460106773 1.015223146314613 1.098421644366289 0.8196181433342711 0.9373224328456391 0.929991183647696 0.7130947064327656 1.1020384205769655 1.0 16.60294993357993 -5.793913735378545 1.5376970454588805 0.9064246828145638 1.1957506671872082 0.437159449650777 0.117863650393991 0.3267898332131015 1.5671777679705388 0.036482251320877464 0.0790162330839649 1.6072604740782038e-06 5.793913735378545 0.28932598437264445 RYDSNSGGER ddPTM_PC-9_AZD4547_30min_R2 2 RYDSNSGGER 10 1 P62191-2;P62191 P62191-2 PSMC1 26S protease regulatory subunit 4 0 ; 108.31 0.0012946 1737140.0 3554.0 976.74 2798.86 2972.4300000000003 3373.2 1941.48 1709.56 3339.3 2296.97 5085.3 False True 4684.098072207712 1292.452103808265 2761.7452876573643 2287.18218708571 2904.8894056703225 1820.0789486850601 1861.7075281434477 2823.2879144801996 2418.383144842805 4907.265194844856 0.9545231175051262 0.2633752309058011 0.5627870469602118 0.466080820227206 0.5919568823633061 0.37089476040485364 0.3793778111073343 0.5753281720837299 0.4928168845212089 1.0 12.260703523247642 -10.106158766432532 1.4721551446668508 1.004063087466802 0.5050957855850485 0.40038064474168955 0.17656079865777102 252.33187519538663 225.7244452279993 6.464716242613642 0.045657328078115844 7.83143294212293e-11 10.106158766432532 -0.4989673018817534 RYDSNSGGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 RYDSNSGGER 10 1 P62191-2;P62191 P62191-2 PSMC1 26S protease regulatory subunit 4 0 ;; 94.363 0.0040064 2117990.0 2291.7200000000003 4102.17 5679.3 4754.08 10579.9 10275.3 3619.12 6948.15 9574.1 8455.8 False True 2679.6629324667774 4509.406327302933 5814.716050865193 4487.724310535315 8506.844543447627 9736.445179368147 3276.2907534402425 6765.768424673454 9714.103100082311 9988.76960392403 0.26826756835137006 0.45144762629537866 0.5821253549166772 0.4492769869046072 0.8516408807853334 0.9747391886527487 0.32799742944848487 0.6773375193292637 0.9725024687991783 1.0 13.286091265418682 -5.267613789103623 0.23811428197897033 0.9582968725020613 5.578090705817303e-26 0.4748953200142163 0.19264942520612197 9.269804860540747 0.5614807464499658 0.34618689047129597 2.6069499471216093 5.399906137768235e-06 5.267613789103623 -0.9582968725020613 RYDSNSGGER ddPTM_PC-9_Lapatinib_30min_R1 1 RYDSNSGGER 10 1 P62191-2;P62191 P62191-2 PSMC1 26S protease regulatory subunit 4 0 84.68700000000001 0.007836599999999999 1159600.0 1321.0 1275.3 1126.5 1013.8 2633.7 929.99 2155.8 1227.4 1263.6 1799.4 False True 1302.16229775827 1272.3471212041982 1033.883518415751 1088.3582339376596 2478.7909440534227 890.2164956125747 2267.416775589589 1284.4294848439954 1121.280061702106 2110.4238924502133 0.6170145734307683 0.6028869961887119 0.489893770684811 0.515705985812201 1.1745464751991286 0.4218188103334201 1.07438926544615 0.608612084728043 0.5313056138690194 1.0 11.043317087440528 RYEDDGIS(ph)DDEIEGK ddPTM_PC-9_AZD4547_30min_R2 2 RYEDDGISDDEIEGK 15 1 I3VM54;Q9Y2K7;Q9Y2K7-3 I3VM54 KDM2A Lysine-specific demethylase 2A 1 RYEDDGIS(1)DDEIEGK;RYEDDGIS(1)DDEIEGK 137.91 1.1231999999999999e-06 3341400.0 21568.9 34013.0 31148.0 27686.0 28459.0 36418.0 33228.0 33460.0 28628.0 29611.0 True False 28427.36153900982 45007.037089533056 30734.957168258356 21303.42044443602 24507.959088097858 34140.776702934105 36185.22762883461 28289.52583430883 30141.217634779667 28574.32790288695 0.9948566991889849 1.57508646371297 1.0756143512006493 0.7455440602780956 0.8576915324619672 1.1948059397570208 1.2663544616627258 0.9900329390232361 1.0548355760883674 1.0 14.802431944740725 -5.499472029790102 24.68818945091191 1.0176091050952398 1.295066358831303 0.23637978784209623 0.19075099575549465 884.5211450946992 932944.9648149404 0.0515245297663706 0.1061413226036731 3.166124367269747e-06 5.499472029790102 0.2774572537360631 RYEDDGIS(ph)DDEIEGK ddPTM_PC-9_Lapatinib_30min_R1 1 RYEDDGISDDEIEGK 15 1 I3VM54;Q9Y2K7;Q9Y2K7-3 I3VM54 KDM2A Lysine-specific demethylase 2A 1 RYEDDGIS(1)DDEIEGK 91.964 0.0017144999999999999 12403000.0 35330.0 54751.0 48937.0 50337.0 56922.0 43545.0 57251.0 56650.0 52216.0 48036.0 True False 34826.18772127148 54624.22742339142 44913.588762282816 54038.95089930946 53573.95987295779 41682.68185835286 60215.176648705565 59282.16581099262 46334.88422114367 56338.95859605338 0.6181546231795471 0.9695640243378215 0.7972030346586682 0.9591755376020557 0.9509220831907731 0.7398553842149433 1.068801734168436 1.0522410652998015 0.8224306124179848 1.0 15.781845275846688 -4.756557502904801 24.996299895547082 0.9265243604427489 0.6181541512894345 0.4472164729451118 0.10361699361602429 143.81006170935777 736253.9902353713 0.025590512252801085 0.20539645893506944 1.75163049363782e-05 4.756557502904801 -0.30837020915331437 RYEEIVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RYEEIVK 7 1 Q5VTE0;P68104;A0A087WVQ9;A0A087WV01 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 0 75.21300000000001 0.020912 5835600.0 18108.0 17804.0 67155.0 28377.0 41287.0 34434.0 25798.0 31307.0 33920.0 19570.0 False True 21173.32675069745 19571.46345746311 68756.2298867556 26787.128689475303 33197.10873120937 32628.220422407405 23354.22667865432 30485.22442250844 34416.01582966462 23117.886083965226 0.9158850715759631 0.8465939916123236 2.9741573099300602 1.158718776975681 1.4359924004572022 1.4113842547670754 1.0102232787993977 1.318685640710604 1.48871811655547 1.0 14.496721862352963 -6.783563272558643 1.9379903880974985 1.2339843889013156 1.516256384207912 0.03984187682949791 0.5701264180954037 1.3271540210473372 10.273766158400255 0.2423708194259983 0.2188182166785474 1.6460261385690356e-07 6.783563272558643 0.2822719953065964 RYESQLR ddPTM_PC-9_AZD4547_30min_R2 2 RYESQLR 7 1 O15212 O15212 PFDN6 Prefoldin subunit 6 0 ; 93.195 0.0089079 3977900.0 15303.5 15810.0 21476.0 29477.0 23524.0 21644.5 17248.199999999997 21012.1 18697.7 22827.0 False True 20169.694667425654 20920.2733185993 21191.21420783087 22681.533065110172 20258.098653797184 20291.065993373 18783.2563858091 17765.16275502334 19686.0222498889 22027.83367799806 0.9156458579752053 0.9497199599566153 0.9620198934494941 1.0296760633236959 0.9196591435149372 0.9211557654732164 0.852705566075264 0.8064870569986017 0.8936885277807315 1.0 14.427040000067835 -6.835685882848601 2.2715584287250836 0.8739514419116481 0.9622859106738588 0.23813075764316738 0.05447219860443651 0.34541010598379346 3.648806312539683 0.021440953585003433 0.018861430434607546 1.4598697752695674e-07 6.835685882848601 0.08833446876221074 RYESQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RYESQLR 7 1 O15212 O15212 PFDN6 Prefoldin subunit 6 0 84.568 0.012572 1083000.0 11161.0 10692.0 10310.0 9920.1 12084.0 11351.0 11594.0 9928.9 14215.0 9148.3 False True 13050.336860201814 11753.431099033682 10555.829500892738 9364.308958398138 9716.226945719814 10755.733577706535 10495.73238670898 9668.276895539144 14422.867482862104 10806.814372097046 1.2076025747141077 1.087594428324852 0.9767753139304081 0.8665189051989803 0.8990833571461074 0.9952732791892492 0.9712142751159608 0.8946463372686793 1.3346086077041934 1.0 13.399653688292846 -10.692866654959683 13.039976946523739 0.9999999108790111 1.0115016803616474 0.0 0.14108478507782915 0.0 0.0 0.13742046375649775 0.03332935806996493 2.0283053913677572e-11 10.692866654959683 0.01150176948263637 RYESQLR ddPTM_PC-9_Lapatinib_30min_R1 1 RYESQLR 7 1 O15212 O15212 PFDN6 Prefoldin subunit 6 0 90.37 0.010108 2144900.0 4837.5 4049.0 6361.5 4658.8 5171.6 4590.9 3269.3 4417.7 4798.0 3807.8 False True 4768.516362911149 4039.624789269817 5838.482026100132 5001.423693301212 4867.416655756798 4394.5579089106 3438.5683571922436 4622.962469606747 4257.598714820119 4465.973156425428 1.0677440718716449 0.904534050648692 1.3073258216297168 1.1198956012768244 1.0898893668345928 0.9840090289364863 0.7699482815397124 1.0351523190316203 0.9533417612899197 1.0 12.124758864257695 -6.830780721920499 4.082259792090794 0.9350374928801743 1.100799174588568 0.31258213879742236 0.11179863441200612 0.2754345345288161 8.99398270839447 0.04152965727528255 0.03714382087141466 1.4764518151367563e-07 6.830780721920499 0.16576168170839356 RYFGGTEDR ddPTM_PC-9_AZD4547_30min_R2 4 RYFGGTEDR 9 1 Q16658 Q16658 FSCN1 Fascin 0 ;;; 99.973 0.0025115 28681400.0 86189.0 76553.9 110894.0 165771.0 126336.0 115681.0 96642.0 112230.0 91605.0 102461.0 False True 113595.30915743139 101298.45108189232 109423.47310314754 127555.05708641936 108796.4271180973 108447.44878280311 105242.95077963892 94887.4322888368 96447.05328468599 98873.8715767011 1.1488910805855335 1.0245219436290645 1.1066975668922059 1.2900785116669464 1.1003556893561997 1.0968261589582373 1.0644162011800764 0.9596815698192638 0.9754554135150607 1.0 16.593301704103403 -7.455035395111597 1.795150151559113 0.9737859621205917 1.1322617462459028 0.5236939739185485 0.06374325705618694 0.3136357666178813 1.9731708573483275 0.04109482492515148 0.021672023046616293 3.5072328874979956e-08 7.455035395111597 0.15847578412531116 RYFGGTEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 RYFGGTEDR 9 1 Q16658 Q16658 FSCN1 Fascin 0 ;;; 109.83 0.0014823 24327600.0 86263.0 73643.0 86088.0 100844.0 109564.0 99012.0 87679.0 103644.0 96464.0 72129.0 False True 100865.62212808803 80953.79035036817 88140.66441055809 95194.03762065942 88095.72071175478 93819.6364193356 79373.41037901105 100923.45481989539 97874.6035080413 85205.41672715016 1.183793542740198 0.9501014543430167 1.0344490737344476 1.1172298813524428 1.0339215990675819 1.1010994373722789 0.9315535728577596 1.1844722870504636 1.148689922161418 1.0 16.378657528744604 -7.7977436864548535 24.99996923994118 1.1249357159817566 1.049739960050443 0.09379868877429731 0.08322308205133189 343.5903665022495 236599.77388391984 0.04291976738649446 0.02061904088998985 1.5931487001167263e-08 7.7977436864548535 -0.07519575593131367 RYFGGTEDR ddPTM_PC-9_Lapatinib_30min_R1 4 RYFGGTEDR 9 1 Q16658 Q16658 FSCN1 Fascin 0 ;;; 109.79 0.001484 24797800.0 120441.0 97300.0 111830.0 105976.0 100150.0 94750.0 85281.0 82526.0 99917.0 78112.0 False True 118723.48925382578 97074.70782809415 102635.76907628351 113769.82856557252 94259.37390247565 90697.76337303776 89696.4328968623 86360.45923597492 88663.29528734516 91613.55512230263 1.2959161894255913 1.0596107497247647 1.1203120426804354 1.24184492582666 1.0288802107574682 0.9900037527411495 0.9790738147550218 0.9426602768627972 0.9677966886994078 1.0 16.48327345451915 -6.445136247202441 4.449576367472802 0.975207249856587 1.1660575644130433 0.7066315019598336 0.06189365336360975 0.13141288685144703 4.788210474413425 0.019758661966452058 0.022129953524501034 3.5880935103750884e-07 6.445136247202441 0.1908503145564563 RYPSS(ph)ISSSPQKDLTQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RYPSSISSSPQKDLTQAK 18 2 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 RY(0.001)PS(0.336)S(0.516)IS(0.016)S(0.032)S(0.1)PQKDLTQAK 78.69 0.012276 149240000.0 34491.0 22370.0 33778.0 49235.0 44535.0 45613.0 34991.0 45835.0 43193.0 31159.0 True False 40329.64507169795 24590.745761820377 34583.39562377835 46476.52257202371 35808.68644717247 43220.973982902666 31676.399167097956 44631.87981619682 43824.61591187217 36807.88004549172 1.0956796485386715 0.6680837291207236 0.9395649948064361 1.26267860345617 0.9728538129040758 1.174231548502246 0.8605874374712249 1.2125631729139315 1.190631350072547 1.0 15.16772703946077 -5.535179057332218 24.47333058007686 1.0939660993044253 0.862367347246141 0.26261544557155925 0.15114895160474504 190.4585183976666 378944.4819437469 0.03887951731352205 0.0674051992643593 2.9162244221056093e-06 5.535179057332218 -0.2315987520582844 RYPSSIS(ph)SSPQK ddPTM_PC-9_AZD4547_30min_R2 1 RYPSSISSSPQK 12 1 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 RYPS(0.016)S(0.08)IS(0.412)S(0.08)S(0.412)PQK 77.185 0.026208 42864000.0 14100.0 15691.0 16750.0 13585.0 12679.0 14316.0 14325.0 13415.0 13619.0 12333.0 True False 18583.50670178075 20762.80889577112 16527.884055744416 10453.188136157747 10918.739705470776 13420.81825688409 15599.897248797875 11342.019996032663 14338.872536260444 11901.225423873047 1.5614784225919711 1.7445942040659392 1.3887548102895864 0.8783287236278513 0.917446676000988 1.1276837282623722 1.3107807551905994 0.9530127858330742 1.2048232031213897 1.0 13.53882250954686 -5.542490243693516 4.621797076268512 1.063180468399199 1.6403116411541747 0.7693195007241784 0.13275185082997001 0.08742984968216493 4.701297354168213 0.03789569829098797 0.07180211562303651 2.8675417933980665e-06 5.542490243693516 0.5771311727549757 RYPSSISS(ph)SPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RYPSSISSSPQK 12 1 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 RYPS(0.006)S(0.153)IS(0.015)S(0.754)S(0.073)PQK 148.48 0.00021936 9454900.0 29450.0 44737.0 32503.0 37834.0 43128.0 29215.0 41114.0 32152.0 23350.0 25156.0 True False 34435.303335986326 49178.19370346708 33277.99478831391 35714.28363948295 34677.377996938456 27682.91396993185 37219.38428041686 31308.044067859933 23691.44957613999 29716.58366521356 1.1587907857758406 1.6549073829450798 1.1198459137572185 1.2018300637058204 1.1669368991945073 0.9315644854000382 1.2524785722251826 1.0535546219099656 0.7972467442101484 1.0 14.8589806470896 -5.989200490261943 0.5268293963916674 0.9706641574076715 1.450393511243253 0.395867874201867 0.1686298000617483 1.4552842074918708 0.7113098142325275 0.12459384746356125 0.3762635818770915 1.0251785475317588e-06 5.989200490261943 0.4797293538355816 RYPSSISS(ph)SPQK ddPTM_PC-9_Lapatinib_30min_R1 3 RYPSSISSSPQK 12 1 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 RYPSSISS(0.888)S(0.111)PQK;RYPS(0.043)S(0.099)IS(0.01)S(0.424)S(0.424)PQK;RYPSSIS(0.002)S(0.921)S(0.077)PQK 194.86 2.2530999999999998e-05 93331000.0 142445.0 237155.0 241877.0 202904.0 273008.0 241067.0 249427.0 274459.0 232346.0 232046.0 True False 140413.70817878642 236605.88216825973 221990.8067322208 217826.23702790137 256950.2061943797 230757.12636462413 262341.10960431566 287211.3671018402 206176.74676815225 272154.84191814 0.515933162126216 0.8693796535114637 0.8156783291733323 0.8003761222569766 0.9441324077991835 0.8478891087818027 0.9639406293687174 1.055323377962274 0.7575714814222083 1.0 18.05406817777577 -4.407386097016714 1.4257603044301332 0.905337611486935 4.891208636850337e-59 0.6073209956849268 0.09084612591494011 2.168161179445972 1.9901442164896055 0.025650121494043093 3.635853046190461 3.913937650227886e-05 4.407386097016714 -0.905337611486935 RYPSSISSS(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 2 RYPSSISSSPQK 12 1 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 RYPSSISS(0.234)S(0.766)PQK;RYPS(0.001)S(0.003)IS(0.006)S(0.314)S(0.676)PQK 118.52 0.00026639999999999997 130736000.0 217480.0 250771.0 288570.0 260226.0 270582.0 293115.0 318917.0 290440.0 253452.0 227624.0 True False 286634.11613498395 331827.82165581704 284743.3732517113 200234.91615162216 233016.3598852977 274786.4727135087 347299.9951759077 245559.1716472404 266848.95528748655 219654.9530433539 1.3049289905081731 1.5106776198682998 1.2963212042639929 0.911588440767376 1.0608290714906239 1.2509914705145453 1.58111615679051 1.1179314112656213 1.2148551698482204 1.0 17.744879505852545 -5.524066122005961 24.99908003236475 1.17810434246446 1.406727371777369 0.23918360974110808 0.17617502582255926 58.38359692765384 1229201.0731229023 0.05103914268298652 0.08931631657476531 2.9918090943728673e-06 5.524066122005961 0.228623029312909 RYPSSISSS(ph)PQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RYPSSISSSPQK 12 1 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 RYPSSISS(0.104)S(0.896)PQK;RYPSSISS(0.03)S(0.97)PQK 142.39 0.00011944 106561000.0 58418.0 80576.0 56702.0 57288.0 65557.0 42573.0 63958.0 46543.0 45787.0 42230.0 True False 68307.01359190661 88575.05277176724 58053.99072353251 54078.339090201946 52711.57645486219 40340.39693451681 57899.43522417913 45321.29556638484 46456.54825450628 49885.964707503925 1.3692631583334252 1.775550563993476 1.163733949296563 1.0840391562492406 1.056641417359084 0.808652236576849 1.1606357732813335 0.9084979278664234 0.9312548835508079 1.0 15.606346353527462 -5.4577970949372485 3.6956792941385737 0.9952643776348976 1.5700717091526644 0.7493151914268709 0.13171955694943693 0.10320615219833658 2.7395989833926726 0.03436889871563593 0.07499732689873756 3.4850009840354384e-06 5.4577970949372485 0.5748073315177668 RYPSSISSS(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 1 RYPSSISSSPQK 12 1 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 RYPSSISS(0.027)S(0.973)PQK 177.36 0.0013578 52969000.0 24444.0 40349.0 39648.0 43365.0 43783.0 38854.0 37902.0 46247.0 40873.0 40085.0 True False 24095.42407751941 40255.57436953517 36388.29448570591 46554.20676139928 41207.77002068991 37192.304993097736 39864.3801040897 48395.80445297396 36269.45232822898 47013.63884009493 0.5125198702332728 0.8562531078790643 0.7739944276483585 0.9902276851987931 0.876506712463755 0.7910960714952954 0.8479322402522036 1.0293992476859772 0.7714666046504165 1.0 15.520791728521651 -4.438736594339788 1.7187717570037175 0.8866773337944686 2.4630075932289207e-15 0.6000331402580673 0.09036099558512767 1.8577013226663992 2.541712522962779 0.02373788460527121 3.616330138472895 3.6413582262027674e-05 4.438736594339788 -0.8866773337944661 RYPSSISSS(ph)PQKDLTQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RYPSSISSSPQKDLTQAK 18 2 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 RYPSSIS(0.016)S(0.34)S(0.641)PQKDLT(0.002)QAK 52.99 0.016396 408140000.0 72758.0 47691.0 52434.0 78411.0 87654.0 88706.0 85995.0 95096.0 74650.0 65135.0 True False 85074.49236399637 52425.44730116117 53684.225417052374 74017.88588189178 70478.82792950384 84054.1012020118 77848.93105011528 92599.83076254083 75741.6150260748 76943.4598916238 1.1056754204168264 0.6813502716800534 0.6977100521950473 0.9619776129920237 0.9159820474511348 1.092413849343446 1.0117680067905297 1.2034789037686804 0.9843801556722063 1.0 16.231511083842918 -6.410286414716397 1.654676369724182 1.0691142809848115 0.8245210335930974 0.3408587006405076 0.12862383993581086 0.3776808167942116 2.0686336790054316 0.047989772078946565 0.057374582430892614 3.8878865654130723e-07 6.410286414716397 -0.24459324739171417 RYS(ph)DFEWLK ddPTM_PC-9_AZD4547_30min_R2 1 RYSDFEWLK 9 1 A0A087X0R6;Q9UMY4-3;Q9UMY4;Q9UMY4-1 A0A087X0R6 SNX12 Sorting nexin-12 1 RY(0.001)S(0.999)DFEWLK 74.69800000000001 0.034135000000000006 0.0 53451.0 38510.0 28433.0 36730.0 38149.0 35801.0 36994.0 32843.0 31569.0 29111.0 True False 70447.30615013347 50957.60439590506 28055.959842207834 28262.465972843118 32852.66984967304 33562.35781047133 40286.39433312592 27767.86900705932 33237.67289060917 28091.832750698784 2.5077504474456584 1.8139651068027054 0.9987230128838761 1.0060741221001357 1.1694740653350868 1.1947372073698703 1.4340963329323466 0.9884676892919559 1.1831792245659862 1.0 14.77786313053886 -4.967841277586308 2.6363038154041885 1.1335244052420517 2.5541245218736193 0.9110451571260353 0.13790744608396435 0.0922876949882393 1.110940665195405 0.03830712957563371 0.24328672966019782 1.0768587032779775e-05 4.967841277586308 1.4206001166315676 up RYS(ph)DFEWLR ddPTM_PC-9_AZD4547_30min_R2 2 RYSDFEWLR 9 1 O60493-4;O60493;O60493-3 O60493-4 SNX3 Sorting nexin-3 1 RY(0.016)S(0.984)DFEWLR;RY(0.256)S(0.744)DFEWLR 104.17 0.0023846999999999996 6356500.0 8317.6 7567.299999999999 8848.4 11961.0 11611.6 9265.3 8158.2 12002.4 8966.7 9169.3 True False 10962.42378317245 10013.281738383072 8731.064434558144 9203.576245607856 9999.529770805624 8685.939326313786 8884.26399547245 10147.704867713932 9440.66145611914 8848.285597917702 1.238931956011035 1.1316634875279719 0.98675210445432 1.040153614364998 1.130109291811156 0.9816522342314401 1.0040661433400402 1.1468554846491423 1.0669480942546479 1.0 13.111182237148121 -4.932756898498135 3.414061841230383 1.0490709663692945 1.238438375145503 0.552517924096183 0.054620006903052576 0.1990617874510327 4.317227588511982 0.014344748787101994 0.08000473428125685 1.167462935456784e-05 4.932756898498135 0.1893674087762085 RYS(ph)DFEWLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RYSDFEWLR 9 1 O60493-4;O60493;O60493-3 O60493-4 SNX3 Sorting nexin-3 1 RY(0.002)S(0.998)DFEWLR 112.02 0.0010066 4775700.0 3368.1 3389.4 4333.2 3641.1 4393.4 3016.0 2882.9 3155.7 3184.5 2343.2 True False 3938.252806992716 3725.877232235758 4436.519921752515 3437.1009716054714 3532.544808285785 2857.83565063544 2609.810841611463 3072.8662187405307 3231.067288017893 2768.0036112390067 1.4227773370678103 1.3460521572686788 1.6027868980151552 1.2417256096233795 1.276206719508056 1.0324537291178688 0.9428495074987514 1.1101380815630737 1.167291572488813 1.0 11.434630109830803 -6.3732322856294745 1.656536530829786 1.0520432638465038 1.4362411504509227 0.7453299707932065 0.0986410799853723 0.18870126891828046 1.031872786453337 0.037118483866528496 0.04566641875798237 4.234164380479301e-07 6.3732322856294745 0.3841978866044189 RYS(ph)DFEWLR ddPTM_PC-9_Lapatinib_30min_R1 2 RYSDFEWLR 9 1 O60493-4;O60493;O60493-3 O60493-4 SNX3 Sorting nexin-3 1 RY(0.044)S(0.956)DFEWLR;RY(0.328)S(0.672)DFEWLR 92.85600000000001 0.0030739 7489600.0 7222.799999999999 7445.1 7380.1 6709.5 8238.6 7020.6 6303.1 6352.4 7996.1 6232.1 True False 7119.801547500702 7427.861328375585 6773.336666009842 7202.939012235872 7754.021745710804 6720.345303817938 6629.443676694839 6647.55569457634 7095.4950153341315 7309.310181248733 0.9740729796589841 1.0162191977337318 0.9266724900232207 0.9854471671915436 1.0608417967543546 0.919422645526561 0.9069862288375694 0.9094641668963435 0.970747558851296 1.0 12.835519542405986 RYS(ph)DHAGPAIPSVVAYPK ddPTM_PC-9_AZD4547_30min_R2 1 RYSDHAGPAIPSVVAYPK 18 1 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 RY(0.028)S(0.972)DHAGPAIPSVVAYPK 121.92 0.00021688 0.0 49389.0 38357.0 56122.0 79746.0 81540.0 63486.0 49004.0 82894.0 65432.0 66853.0 True False 65093.67464498221 50755.15013798313 55377.785610536615 61361.79176341812 70219.57848285254 59516.210383944104 53365.26106667301 70084.63701462025 68890.60193792437 64512.49681846951 1.0090087634981493 0.7867491205742987 0.8584040045196687 0.9511613220626525 1.0884647463024424 0.9225532000631698 0.8272081177827686 1.0863730357829753 1.0678644500735155 1.0 15.977291033910108 -6.640545017058238 0.47212650158658814 1.0323863886122733 0.8726699125221321 0.17573793492330114 0.09415867255075787 2.1350317123786677 0.9886350348906644 0.0929864426035038 0.1468757157937015 2.2879945358199775e-07 6.640545017058238 -0.15971647609014117 RYS(ph)DHAGPAIPSVVAYPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RYSDHAGPAIPSVVAYPK 18 1 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 RY(0.114)S(0.883)DHAGPAIPS(0.002)VVAY(0.001)PK 51.044 0.029675999999999998 4615800.0 42799.0 45951.0 44710.0 46519.0 49122.0 41116.0 40686.0 46983.0 40359.0 35295.0 True False 50044.025381218285 50512.711600420575 45776.05596361925 43912.69124663285 39496.8967252275 38959.804579418706 36831.92753886851 45749.74603260337 40949.17402327338 41693.704104933735 1.2002777506951328 1.2115189255742633 1.0979129090668256 1.0532211562713263 0.9473108128225461 0.9344289603381265 0.8833930285054737 1.097281880196144 0.9821428655082662 1.0 15.347541927671614 -5.641985993082966 1.6005220359137329 0.9735661128389452 1.2120166954054565 0.7400399473334482 0.05374682404576993 0.21005855293603187 1.066054889696523 0.01793827312243271 0.046079121938832755 2.2804156190488457e-06 5.641985993082966 0.2384505825665113 RYS(ph)DHAGPAIPSVVAYPK ddPTM_PC-9_Lapatinib_30min_R1 2 RYSDHAGPAIPSVVAYPK 18 1 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 RY(0.009)S(0.991)DHAGPAIPSVVAYPK;RY(0.008)S(0.992)DHAGPAIPSVVAYPK 98.3 0.0033996 0.0 122414.0 107791.0 119221.0 103340.0 98114.0 106188.0 90196.0 94705.0 129096.0 105708.0 True False 120668.35391202175 107541.41656215907 109419.10958636845 110939.96833213427 92343.12741954581 101646.58677631819 94865.90754758245 99105.34003760028 114555.84903885331 123979.48695294403 0.9732928960886972 0.8674129826249081 0.8825581737396452 0.8948251929308365 0.744825855381982 0.8198661671740728 0.7651742226001343 0.7993688510359408 0.9239903459378935 1.0 16.919741913441122 -3.564311307188625 0.83563807888106 0.8342159215275016 1.8188940866136218 0.16686837347207106 0.07378241676131986 22.981636166820216 2.566816556576895 0.025262148577867127 33.253946584672384 0.00027270223216501095 3.564311307188625 0.9846781650861203 RYS(ph)DLTTLVAFPSSSVYPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RYSDLTTLVAFPSSSVYPTK 20 1 P25205;J3KQ69;A0A499FHX9;P25205-2 P25205 MCM3 DNA replication licensing factor MCM3 1 RY(0.227)S(0.258)DLT(0.258)T(0.258)LVAFPSSSVYPTK 97.05799999999999 0.0011237999999999999 0.0 8535.9 11444.0 9746.5 8123.4 7717.4 5634.7 7493.6 5904.9 5789.8 6109.8 True False 9980.859278290176 12580.084689238809 9978.893523807086 7668.272234418142 6205.23086981944 5339.206412677559 6783.751959034193 5749.90263175871 5874.464871774534 7217.458374849813 1.3828772900263337 1.7430075846472182 1.3826049289843998 1.0624615808162123 0.8597529140510719 0.7397626886609736 0.9399087056287118 0.7966658528707289 0.813924316106191 1.0 12.817275166711717 -5.802113296519878 2.148824932054922 0.8477833135319635 1.5685894955360156 0.876713983454151 0.10901372177776224 0.08897141686202262 0.8388357061118158 0.031407275512396 0.05806898276465886 1.5771997642302664e-06 5.802113296519878 0.7208061820040521 RYS(ph)GDSDSSASSAQSGPLGTR ddPTM_PC-9_AZD4547_30min_R2 3 RYSGDSDSSASSAQSGPLGTR 21 1 A0A5E8;Q99501 A0A5E8 GAS2L1 GAS2-like protein 1 1 RY(0.019)S(0.948)GDS(0.033)DSSASSAQSGPLGTR;RYS(0.967)GDS(0.033)DSSASSAQSGPLGTR;RY(0.005)S(0.992)GDS(0.003)DSSASSAQSGPLGTR 132.88 1.1872000000000001e-05 15976000.0 14953.2 17702.3 23989.800000000003 39586.0 27813.9 26435.399999999998 21285.3 30104.8 23970.3 25309.699999999997 True False 19708.00655411827 23424.222287655917 23671.679577343148 30460.059297603264 23952.42008786131 24782.390259013257 23179.650464910115 25452.794899482975 25237.321121662673 24423.61510667313 0.8069242193688829 0.959080880752 0.9692127669861398 1.2471560481347754 0.9807074007367943 1.0146896825377052 0.9490671370176018 1.042138716496914 1.033316362521911 1.0 14.575989138861656 -4.808097447327622 1.9104653711599862 1.0334752416613464 0.7478103315119018 0.4334950164556064 0.07787589555906842 0.7361797563032255 3.0053941905587966 0.02168875356493999 0.37211710405724957 1.5556165420139576e-05 4.808097447327622 -0.2856649101494446 RYS(ph)GDSDSSASSAQSGPLGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RYSGDSDSSASSAQSGPLGTR 21 1 A0A5E8;Q99501 A0A5E8 GAS2L1 GAS2-like protein 1 1 RY(0.205)S(0.79)GDS(0.003)DS(0.001)SASSAQSGPLGTR;RY(0.427)S(0.475)GDS(0.041)DS(0.049)S(0.005)AS(0.002)S(0.001)AQSGPLGTR 63.291000000000004 0.0026984 12315500.0 30545.0 29648.0 32114.0 35142.0 40909.0 30594.0 34912.0 27967.0 29813.0 28937.0 True False 35715.6652087505 32591.25750319403 32879.71955302322 33173.10767190122 32893.175117713676 28989.59678234107 31604.882619008422 27232.89588348591 30248.95872434523 34183.04903483403 1.0448355608171367 0.9534333075432242 0.9618720530025668 0.9704549069948781 0.9622656856675975 0.8480693677383604 0.9245776345697441 0.7966783728313525 0.8849110766427012 1.0 15.060993466769675 -6.663501400827637 5.78978068304659 0.8805059244174527 0.977372574201653 0.3873932666765947 0.05459673694397328 0.20029649204527403 9.859680068097529 0.01739446097098793 0.01730717409038451 2.170194203541764e-07 6.663501400827637 0.09686664978420034 RYS(ph)GDSDSSASSAQSGPLGTR ddPTM_PC-9_Lapatinib_30min_R1 3 RYSGDSDSSASSAQSGPLGTR 21 1 A0A5E8;Q99501 A0A5E8 GAS2L1 GAS2-like protein 1 1 RY(0.002)S(0.995)GDS(0.002)DSSASSAQSGPLGTR;RY(0.089)S(0.528)GDS(0.027)DS(0.089)S(0.089)AS(0.089)S(0.089)AQSGPLGTR;RY(0.004)S(0.934)GDS(0.062)DSSASSAQSGPLGTR 122.83 1.8916999999999998e-06 17423300.0 27919.0 24727.9 22071.0 23605.199999999997 29379.4 23721.2 17168.7 23448.9 28019.9 23758.5 True False 27520.869940282468 24670.64406682764 20256.407576523783 25341.205152638824 27651.361454122765 22706.699572817994 18057.611278905733 24538.4214984181 24864.003799372294 27865.1250687887 0.9876456636151321 0.8853591722960128 0.7269447930529002 0.9094237004169459 0.9923286325061083 0.8148787962287461 0.6480362544337469 0.8806140807852756 0.8922983025553359 1.0 14.766173008318646 RYS(ph)GNMEYVISR ddPTM_PC-9_Lapatinib_30min_R1 1 RYSGNMEYVISR 12 1 O95835;O95835-2 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 RY(0.066)S(0.934)GNMEYVISR 70.78399999999999 0.013272999999999998 2204500.0 7088.3 8588.7 11105.0 8204.6 8844.8 7754.1 7774.3 7565.9 8126.0 7285.4 True False 6987.219542164981 8568.81339283816 10191.989766539646 8807.993653743262 8324.566253545861 7422.475218689949 8176.815214057948 7917.439334675889 7210.76430942649 8544.671682814707 0.8177282640616702 1.0028253525611763 1.192788926816003 1.0308170963968288 0.9742406218238288 0.8686671055622005 0.9569490224537704 0.926593745035245 0.8438901548352045 1.0 13.06080934406791 -6.526402125982031 4.910728221665889 0.916847711844554 1.021762961853475 0.17319668129761134 0.09362182204468515 0.3107228666894096 21.253229913741258 0.03218304384961184 0.033822825248703954 2.975759810235458e-07 6.526402125982031 0.10491525000892088 RYS(ph)PDELR ddPTM_PC-9_AZD4547_30min_R2 2 RYSPDELR 8 1 S5FZ81;Q8WUB8-3;Q8WUB8-2;Q8WUB8 S5FZ81 PHF10 PHD finger protein 10 1 RY(0.498)S(0.502)PDELR;RY(0.192)S(0.808)PDELR 109.48 0.0017315999999999998 8664600.0 11195.4 12936.0 15781.900000000001 24650.0 25571.0 16169.599999999999 12021.099999999999 17993.300000000003 9203.4 15098.2 True False 14755.30432121391 17117.30902273248 15572.62169428972 18967.323338703587 22020.908037589186 15158.512355861487 13090.954612043572 15212.848929900447 9689.872934886507 14569.616613534425 1.012744858880294 1.1748633801956998 1.0688422425490287 1.3018409366437218 1.5114267328855375 1.0404194398485413 0.8985105757609811 1.0441488841764368 0.6650739818290835 1.0 13.830675294218185 -6.994255813352802 24.985581954623648 0.9147341966072063 1.2153273783039078 0.46850478152157304 0.1568139592575299 144.06197862589892 626624.1424661424 0.057278742987299264 0.05037291707325995 1.0133143353305522e-07 6.994255813352802 0.30059318169670146 RYS(ph)PDELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RYSPDELR 8 1 S5FZ81;Q8WUB8-3;Q8WUB8-2;Q8WUB8 S5FZ81 PHF10 PHD finger protein 10 1 RY(0.052)S(0.948)PDELR;RY(0.382)S(0.618)PDELR 91.12299999999999 0.004108 6187500.0 13580.0 14361.099999999999 19812.4 19263.8 18802.4 16300.800000000001 16764.9 16984.4 11996.7 10494.900000000001 True False 15878.825782774 15786.77509879653 20284.80275494542 18184.51174008225 15118.204694157768 15445.957352081636 15176.807304634924 16538.57749645932 12172.129041973394 12397.542292417316 1.2808043246189154 1.2733794107282186 1.6361954875001454 1.4667836020373495 1.2194517540306746 1.245888659845816 1.22417870789741 1.3340206555758052 0.9818179083299606 1.0 13.597766526454102 -7.891735939586749 0.5895204077119602 0.9855170372530537 1.4006117452948388 0.5256534449508936 0.12663879238737705 0.6709645166099173 0.5098850085611213 0.13283903614666467 0.0724078946432977 1.2831105043922815e-08 7.891735939586749 0.41509470804178505 RYS(ph)PDELR ddPTM_PC-9_Lapatinib_30min_R1 2 RYSPDELR 8 1 S5FZ81;Q8WUB8-3;Q8WUB8-2;Q8WUB8 S5FZ81 PHF10 PHD finger protein 10 1 RY(0.06)S(0.94)PDELR;RY(0.343)S(0.657)PDELR 95.618 0.0029208000000000003 8647800.0 17142.4 18175.8 20803.9 16195.199999999999 19193.3 20065.8 12849.599999999999 17630.6 18353.1 16042.3 True False 16897.946232468843 18133.715051817835 19093.48364737633 17386.249033603446 18064.387829479663 19207.632509664414 13514.889414424326 18449.782039669662 16285.980611289102 18815.190179978912 0.898101271941955 0.9637805878313029 1.0147908931419438 0.92405385580976 0.960095946768682 1.0208577391953815 0.7182967211676344 0.9805790886611352 0.8655761889996136 1.0 14.199610251486511 RYS(ph)PPIQR ddPTM_PC-9_AZD4547_30min_R2 2 RYSPPIQR 8 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 RY(0.013)S(0.987)PPIQR;RY(0.001)S(0.999)PPIQR 58.699 0.035132 1653420000.0 25142.0 27487.0 43170.0 59664.0 43978.0 36415.0 27264.0 43629.0 32015.0 33525.0 True False 33136.63301391288 36371.63521241862 42597.537593223075 45909.38659961099 37872.41381553703 34137.96429340837 29690.443182633517 36887.14054468199 33707.2475400821 32351.299954215843 1.0242751623832258 1.1242712120963434 1.316717957346626 1.419089392530835 1.170661267681199 1.0552269720759613 0.9177511637755509 1.1402058216172257 1.0419132334028376 1.0 14.981536063940965 -6.707222817748407 3.983771125405265 1.0311486868844506 1.228071966433906 0.40027731371910047 0.11112183524007282 0.24506113656042194 7.947049438404352 0.04213530132021286 0.04081503835910007 1.9623532198050777e-07 6.707222817748407 0.19692327954945532 RYS(ph)PPIQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 RYSPPIQR 8 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 RY(0.321)S(0.679)PPIQR;RY(0.315)S(0.685)PPIQR;RY(0.017)S(0.983)PPIQR;RY(0.398)S(0.602)PPIQR;RY(0.003)S(0.997)PPIQR 66.056 0.022965 1688390000.0 88715.1 87231.0 113591.0 111399.0 139838.0 133004.0 118272.0 88764.0 108742.0 99556.0 True False 103732.8142269051 95890.71719040474 116299.44023626631 105157.67519043102 112437.7477354824 126029.03609983946 107068.41994487187 86434.03905323202 110332.14603034736 117604.71471513782 0.8820463914067286 0.8153645661457645 0.988901172184864 0.8941620703314828 0.9560649673597623 1.071632514096965 0.9104092485085572 0.7349538601627713 0.9381609087492276 1.0 16.843586372704664 -5.250285643294873 24.843213801597482 0.9303598896892917 0.8487054783759809 0.145304297156594 0.08430388629919582 1499.2233582524927 3339268.6492407727 0.022928863379430117 0.059433083128047244 5.619715847885253e-06 5.250285643294873 -0.08165441131331086 RYS(ph)PPIQR ddPTM_PC-9_Lapatinib_30min_R1 1 RYSPPIQR 8 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 RY(0.031)S(0.969)PPIQR 64.374 0.025069 419700000.0 14330.0 9191.9 13913.0 12409.0 10772.0 13011.0 13889.0 13541.0 12503.0 11164.0 True False 14125.651572199848 9170.61672029865 12769.126845733106 13321.59925521051 10138.412138566842 12454.549860122374 14608.104460601064 14170.164293850854 11094.780477573142 13093.682524905062 1.0788142713351963 0.7003848384788254 0.9752128036895176 1.0174066180291095 0.774297995944449 0.9511877072346138 1.115660505195194 1.082213828454925 0.8473384364154336 1.0 13.67658328380406 -7.006240507133725 24.90414803692639 1.0203357477692871 0.9028419792431163 0.13104851219517566 0.12251473722985273 491.70339390287813 1962258.476728778 0.04307790863877888 0.036711972097449155 9.857334469573061e-08 7.006240507133725 -0.11749376852617088 RYS(ph)TSGSSGLTTGK ddPTM_PC-9_AZD4547_30min_R2 2 RYSTSGSSGLTTGK 14 1 D6RAW4;A0A087WYS0;B9A067;Q16891-3;Q16891-2;Q16891-4;Q16891 D6RAW4 IMMT MICOS complex subunit MIC60 1 RY(0.072)S(0.425)T(0.367)S(0.126)GS(0.005)S(0.005)GLTTGK;RY(0.011)S(0.501)T(0.2)S(0.2)GS(0.033)S(0.053)GLTTGK 97.2 0.0012655 7655000.0 49185.0 38337.0 46032.0 65988.0 51769.0 38481.0 49039.0 58717.0 44543.0 46824.0 True False 64824.80688844579 50728.68552910445 45421.58560322551 50775.48610443699 44581.767947986176 36074.77698680895 53403.37599886903 49643.63683243012 46897.452043663216 45184.70601211639 1.4346625796583221 1.1226959298020314 1.005242472774872 1.1237316912236062 0.9866561472377726 0.7983846785931376 1.181890526952832 1.0986823023506684 1.037905437098286 1.0 15.463546915591948 -4.750540716091244 2.576083392694223 1.031665839151197 1.539512369677869 0.6117111639573587 0.0969404674951478 0.39552887039976364 3.1597102008103355 0.02620672749818663 0.4585714689872375 1.776066750202669e-05 4.750540716091244 0.507846530526672 RYS(ph)TSGSSGLTTGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 RYSTSGSSGLTTGK 14 1 D6RAW4;A0A087WYS0;B9A067;Q16891-3;Q16891-2;Q16891-4;Q16891 D6RAW4 IMMT MICOS complex subunit MIC60 1 RY(0.002)S(0.783)T(0.157)S(0.052)GS(0.006)SGLTTGK 82.709 0.0040914 3681400.0 55545.0 47524.0 53170.0 49141.0 58656.0 52162.0 56180.0 60576.0 52058.0 45335.0 True False 64947.6714362431 52241.868644825685 54437.774448347904 46387.789087271594 47162.777865619166 49426.53289404704 50858.22369202264 58985.94418557737 52819.24976593986 53553.87662833744 1.2127538756340333 0.9755011575984114 1.0165048335556488 0.8661891912923818 0.8806603897777122 0.9229309996933731 0.9496646535035631 1.1014318271474228 0.9862824708751549 1.0 15.708703391313943 -4.75332482381426 4.538740766614565 0.9623417711341948 1.2355336268498704 0.5653017420086467 0.06475351953115177 0.17798379280498655 8.06148175475858 0.017963979418309503 0.16056887811288703 1.7647174339631485e-05 4.75332482381426 0.2731918557156756 RYSLGDAR ddPTM_PC-9_Lapatinib_30min_R1 1 RYSLGDAR 8 1 A0A6I8PRV1 A0A6I8PRV1 0 81.95 0.010858 1721400.0 17709.0 16584.0 24871.0 14657.0 18801.0 20572.0 18927.0 21267.0 19660.0 12466.0 False True 17456.466412567144 16545.600766917923 22826.202384836342 15734.924674318676 17695.162144188176 19692.18351567425 19906.947449477746 22255.14245900054 17445.683771021988 14620.73149009912 1.1939530128426425 1.1316534181701023 1.5612216393067482 1.0762063912447928 1.210278853432949 1.3468671884857073 1.3615561890975394 1.522163407082012 1.1932155229603847 1.0 13.835727872148878 -6.762819188913365 24.977785256173348 1.3221954110654885 1.2382789642209502 0.0 0.17529066277843405 129.7674995617972 2349065.6960207256 0.058721209361499285 0.054599334169346474 1.7265565646998515e-07 6.762819188913365 -0.08391644684453836 RYSPPIQR ddPTM_PC-9_AZD4547_30min_R2 1 RYSPPIQR 8 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 0 75.378 0.01674 1944700.0 10126.0 9704.0 12785.0 19058.0 17761.0 11208.0 8744.1 17533.0 13958.0 13167.0 False True 13345.85736611572 12840.628227937219 12615.462546429399 14664.472543164831 15295.191727176163 10507.161988205982 9522.307960433753 14823.67771825872 14695.791384178227 12706.027337722886 1.0503564183663643 1.010593467701326 0.9928722968331251 1.154135132357816 1.2037745017096189 0.8269431277714397 0.7494323526412541 1.1666650263098952 1.1566000130149205 1.0 13.633225407842565 -4.385902038448226 15.21133185471825 1.027582586138904 3.8113128586458185 0.001929443518077889 0.14245228595895112 215205.92663929416 124284.87588267076 0.03835231675757364 20712704.288412765 4.112424724730813e-05 4.385902038448226 2.783730272506914 RYSPPIQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 RYSPPIQR 8 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 0 ; 66.962 0.030133999999999998 4203400.0 17439.8 15435.7 24159.0 22055.2 19972.9 19200.4 18401.4 18830.5 18270.1 14385.7 False True 20392.01368824904 16968.054285012557 24735.042183517708 20819.51864792316 16059.353621662309 18193.49722362757 16658.286177400943 18336.21932756397 18537.265648866593 16993.713532861464 1.199973957947222 0.9984900741206865 1.4555407289693632 1.2251306112500704 0.9450173201170925 1.0706016191485184 0.9802616800140893 1.0790001427355147 1.0908307718039554 1.0 14.052713529895616 -6.244743038213153 24.109216892448995 1.0313499053783746 1.220816955873748 0.41780809769098626 0.11107335095819978 543.8882248001183 785364.0177269204 0.03342199617751614 0.04300743866402524 5.691896072785623e-07 6.244743038213153 0.1894670504953735 RYWEEETVPTTAGAS(ph)PGPPR ddPTM_PC-9_AZD4547_30min_R2 2 RYWEEETVPTTAGASPGPPR 20 1 O15213 O15213 WDR46 WD repeat-containing protein 46 1 RYWEEETVPTT(0.005)AGAS(0.995)PGPPR;RYWEEETVPTTAGAS(0.999)PGPPR 187.57 1.6588000000000003e-11 23822300.0 31593.0 31708.0 42811.0 62276.0 46563.0 42832.0 37362.0 53282.0 40338.0 42114.0 True False 41638.91682477721 41956.990916264775 42243.29816778954 47919.230354608706 40098.53118588497 40153.70826898988 40687.14562021545 45048.49119855476 42470.18432834085 40639.60167850394 1.0245896885057773 1.032416391483917 1.0394614224315555 1.1791264770184813 0.9866861270713397 0.988043844195179 1.0011698919218655 1.1084875180354652 1.0450443059043364 1.0 15.310598641421752 RYWEEETVPTTAGAS(ph)PGPPR ddPTM_PC-9_Lapatinib_30min_R1 2 RYWEEETVPTTAGASPGPPR 20 1 O15213 O15213 WDR46 WD repeat-containing protein 46 1 RYWEEET(0.001)VPT(0.184)T(0.184)AGAS(0.632)PGPPR;RYWEEETVPTTAGAS(1)PGPPR 121.48 1.4602999999999999e-05 10941900.0 20917.0 20300.9 20387.4 19618.9 18500.7 16473.199999999997 18617.3 21864.1 23805.0 17680.699999999997 True False 20618.71974429199 20253.894513333584 18711.226669639847 21061.739352731856 17412.52519977567 15768.679636904775 19581.21269885148 22879.98590482125 21123.830222236953 20736.785436948125 0.9943064611911464 0.9767133182197979 0.9023205031721453 1.0156704093202769 0.8396925961702147 0.7604206391993938 0.9442742588232753 1.1033525892617106 1.0186646472504464 1.0 14.33990464816481 -7.614134301483963 6.607475476342584 1.044223207408982 0.9130306571733645 0.3606024509758142 0.0749380674864675 0.24620741225365483 14.85673898029148 0.038674461558697804 0.02209386252879588 2.4314519891425714e-08 7.614134301483963 -0.13119255023561738 S(ph)AASPVVSSMPER ddPTM_PC-9_AZD4547_30min_R2 1 SAASPVVSSMPER 13 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 S(0.995)AAS(0.005)PVVSSMPER 202.29 1.0652999999999999e-07 10329000.0 11853.0 14855.0 20636.0 30723.0 29007.0 21470.0 14599.0 19245.0 16599.0 20000.0 True False 15622.007442284188 19656.588244642156 20362.35315667713 23640.28701561828 24979.8787472664 20127.477505958464 15898.282717989554 16271.127456105007 17476.389252469875 19299.80608752621 0.8094385700787406 1.0184863078674424 1.055054805438572 1.2248976444844903 1.2943072398748772 1.0428849603295856 0.8237534950294078 0.8430720693417387 0.905521494527614 1.0 14.236298731811214 -7.1431407881065985 5.376787617201888 0.8812027468779086 1.0909067885300903 0.32140328975188703 0.1284939163467185 0.2754653409400839 11.062932663886839 0.05430374389766041 0.04184508625720829 7.192157872828858e-08 7.1431407881065985 0.2097040416521817 S(ph)AASPVVSSMPER ddPTM_PC-9_Lapatinib_30min_R1 1 SAASPVVSSMPER 13 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 S(0.996)AAS(0.004)PVVSSMPER 171.99 0.00021461 21806000.0 22762.0 9798.0 18527.0 15760.0 16248.0 24065.0 13579.0 16548.0 18589.0 15105.0 True False 22437.40970596042 9775.313332987327 17003.781576288166 16919.042973818814 15292.324584797061 23035.79604825494 14282.054177442718 17316.880491444066 16495.31106915197 17715.879123852657 1.2665140436497275 0.5517825711412676 0.9598045604970445 0.9550213599639555 0.8631987426583577 1.3002908795668822 0.8061724782380888 0.9774779095285551 0.931103161961784 1.0 14.112755438353297 S(ph)AASQTADGSGCR ddPTM_PC-9_AZD4547_30min_R2 1 SAASQTADGSGCR 13 0 Q13905-2;Q13905;Q13905-4;Q13905-3 Q13905-2 RAPGEF1 Rap guanine nucleotide exchange factor 1 1 S(1)AASQTADGSGCR 72.321 0.023859 3509700.0 6367.8 5197.6 7820.4 10726.0 9741.5 8861.0 6156.7 8027.2 7640.0 7759.7 True False 8392.627941531875 6877.622555392263 7716.696386241409 8253.286415048067 8389.060875529898 8306.920269226734 6704.63437289172 6786.780686705436 8043.834802630872 7488.035264868856 1.120805076988224 0.9184815925827129 1.0305368649164017 1.1021965205972644 1.1203287082378375 1.1093591276472468 0.8953796470948036 0.906349989902765 1.0742250160558973 1.0 12.870371513965297 -7.254837930856456 24.97942935700181 0.961184495285624 1.0625757886103473 0.29611665074974347 0.07341394518139278 695.483129364847 2631667.58169187 0.029981929660265798 0.022678013086215264 5.5611174721889815e-08 7.254837930856456 0.1013912933247233 S(ph)AASQTADGSGCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAASQTADGSGCR 13 0 Q13905-2;Q13905;Q13905-4;Q13905-3 Q13905-2 RAPGEF1 Rap guanine nucleotide exchange factor 1 1 S(1)AASQTADGSGCR 91.845 0.0049123000000000005 2741600.0 3926.2 4837.3 4540.4 4902.9 6406.1 3642.1 3487.8 2979.5 6297.0 4142.1 True False 4590.828114015266 5317.515175398019 4648.660355562886 4628.2064084162685 5150.870691573629 3451.1018644493843 3157.410334514713 2901.2912820412007 6389.081712246403 4893.02994115444 0.9382383041237075 1.0867530424601137 0.9500576149072372 0.9458773937778745 1.0526955186295786 0.7053097785939864 0.645287352108409 0.592943700924234 1.3057516077122127 1.0 12.256512395518646 -6.7520514415195905 24.992643721099558 0.8116317670692528 0.9946418808101019 0.10477754473655987 0.1964276352487824 365.2526591409111 972377.1327051596 0.0648009996699374 0.06396644440419717 1.7698993040255144e-07 6.7520514415195905 0.18301011374084908 S(ph)AASREDLVGPEVGASPQSGRK ddPTM_PC-9_AZD4547_30min_R2 2 SAASREDLVGPEVGASPQSGRK 22 2 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 S(0.783)AAS(0.216)REDLVGPEVGASPQSGRK;S(0.531)AAS(0.469)REDLVGPEVGASPQSGRK 77.322 0.0020670000000000003 13025300.0 13530.0 11951.300000000001 26091.9 44233.0 34712.2 28295.0 22323.0 31110.2 21089.3 33710.7 True False 17832.258558517267 15814.324004590495 25745.904357855412 34035.76524303757 29893.01020618682 26525.709177042136 24309.70375461886 26302.833431276602 22204.037343340733 32530.498653738494 0.5481704645332246 0.4861383827195981 0.7914389702998488 1.0462724720368246 0.9189225939747909 0.815410469399421 0.7472896131527673 0.8085591835295709 0.6825606204099482 1.0 14.989505316891968 -5.326333463569719 4.801354944722286 0.8518661817141552 0.5164183746111488 0.6211850857832457 0.10504063038068005 0.13429089748807096 6.1539399116055105 0.029464983769373815 0.06553864837198277 4.717007170464186e-06 5.326333463569719 -0.33544780710300637 S(ph)AAVETASLSPSLVPAR ddPTM_PC-9_AZD4547_30min_R2 1 SAAVETASLSPSLVPAR 17 0 Q2KHT3;Q2KHT3-3 Q2KHT3 CLEC16A Protein CLEC16A 1 S(0.666)AAVETAS(0.002)LS(0.331)PS(0.001)LVPAR 203.85 3.5936999999999996e-17 29674000.0 13431.0 19291.0 27435.0 28829.0 28928.0 26025.0 19574.0 26005.0 23825.0 22380.0 True False 17701.77861784518 25526.43849393415 27071.19397428945 22182.91945360999 24911.846533627147 24397.652635890514 21316.048080137512 21986.524785451318 25084.340860298493 21596.483011941844 0.8196602478309511 1.1819720127494475 1.2535001166310435 1.0271542566140919 1.1535140476276653 1.129704897894706 0.9870147870072519 1.0180604301771636 1.161501196580389 1.0 14.398508768125522 -7.240936170359286 23.78541232565861 1.0431491210408945 1.1051207801887373 0.04113607129782959 0.1175095290896232 1422.863137175039 1650639.3980102756 0.04479667317172725 0.03465345745107973 5.742008481300902e-08 7.240936170359286 0.06197165914784275 S(ph)ADFNPDFVFTEK ddPTM_PC-9_AZD4547_30min_R2 1 SADFNPDFVFTEK 13 0 A0A087WYH5;B7Z6D5;Q96GQ7 A0A087WYH5 DDX27 Probable ATP-dependent RNA helicase DDX27 1 S(1)ADFNPDFVFTEK 89.506 0.025807 0.0 2534.2 3378.8 3616.7 3975.3 4138.3 3367.4 2945.2 3483.0 3607.9 3195.7 True False 3340.0228853654444 4470.931023964786 3568.7401948902 3058.8560027727563 3563.768477257649 3156.8359456713806 3207.317094391587 2944.7823813776936 3798.6062283261695 3083.819515695377 1.0830798846580019 1.449803077388148 1.1572467768385197 0.9919050019641011 1.1556345820887146 1.023677270866333 1.0400469541319322 0.9549139845538815 1.2317861693892334 1.0 11.590502616895991 -5.518705678463969 18.79028210800651 1.0583577340279835 1.275712789021163 0.35775102079960575 0.11270106076427243 6.122724077972411 27564.081674689478 0.02810823093522141 0.05084376174507384 3.0289654637401593e-06 5.518705678463969 0.21735505499317953 S(ph)ADGSAPAGEGEGVTLQR ddPTM_PC-9_Lapatinib_30min_R1 1 SADGSAPAGEGEGVTLQR 18 0 Q01650 Q01650 SLC7A5 Large neutral amino acids transporter small subunit 1 1 S(1)ADGSAPAGEGEGVTLQR 210.39 1.3017000000000002e-20 4000000.0 16767.0 23966.0 10172.0 4080.3 7624.7 5077.6 6100.7 4498.3 15345.0 2395.6 True False 16527.899505308786 23910.508199466658 9335.697425055501 4380.378873481784 7176.230136736961 4860.442884463712 6416.564395045642 4707.307439851513 13616.684509986393 2809.6762680636493 5.8824924754407215 8.510058070122476 3.322695048952883 1.55903330332808 2.5541128059150453 1.7298942727709319 2.28373797649925 1.675391394146507 4.846353533594328 1.0 11.456188196829018 -5.3883221114985105 4.715390494102329 2.2708269722809113 7.1554698548102245 0.7429876376024764 1.147208380825167 0.09652188647399848 3.2403824192815787 0.2859667971745467 0.6205165078009921 4.089572280852945e-06 5.3883221114985105 4.884642882529313 S(ph)ADLPHSFK ddPTM_PC-9_AZD4547_30min_R2 2 SADLPHSFK 9 0 F8W1R0;B7Z493;E9PJX4;F8VWL3;Q96M96 F8W1R0 FGD4 FYVE, RhoGEF and PH domain-containing protein 4 1 S(1)ADLPHSFK;S(1)ADLPHSFK 77.67399999999999 0.012872999999999999 6442700.0 71785.0 61604.0 84210.0 72609.0 78856.0 83889.0 83703.0 92735.0 78739.0 81617.0 True False 94611.13677924313 81516.288268121 83093.32037816345 55870.11684786738 67908.20555364029 78643.40756857717 91152.40484580296 78404.93658830335 82900.98279114549 78759.61367228154 1.2012646122531747 1.0350011188133803 1.0550244789660148 0.7093752018685964 0.8622211611677792 0.9985245470579895 1.1573495678265737 0.9954967137668551 1.0525823950342896 1.0 16.265168414170702 -9.618509532241406 15.743556915955555 1.0000014223936484 1.0003974170509162 0.0 0.132552081724133 0.0 0.0 0.13857203062705645 0.03360865406068702 2.407079685967055e-10 9.618509532241406 0.00039599465726780636 S(ph)ADLPHSFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SADLPHSFK 9 0 F8W1R0;B7Z493;E9PJX4;F8VWL3;Q96M96 F8W1R0 FGD4 FYVE, RhoGEF and PH domain-containing protein 4 1 S(0.998)ADLPHS(0.002)FK;S(1)ADLPHSFK 105.13 0.0015055 7869500.0 70050.0 76014.0 72241.0 75757.0 95113.0 71924.0 85340.0 63983.0 66400.0 64372.0 True False 81908.08144943425 83560.16756097502 73963.49941551813 71512.5808975078 76476.29042438339 68152.17882503434 77255.97739190474 62303.51404559227 67370.97438354169 76042.13403152826 1.077140752197642 1.0988666825990137 0.9726646990844801 0.940433639958836 1.0057094188423898 0.896242322667817 1.0159627734786245 0.8193288476065158 0.8859690123321451 1.0 16.21451139961458 -5.049266081776676 0.6337264774700498 0.9168525160414898 1.1841635379768813 0.47360811067326736 0.060023106272826206 2.172702926086019 0.8311247471327907 0.03003775634306007 0.40177608155609723 8.92758344589656e-06 5.049266081776676 0.2673110219353916 S(ph)ADLPHSFK ddPTM_PC-9_Lapatinib_30min_R1 2 SADLPHSFK 9 0 F8W1R0;B7Z493;E9PJX4;F8VWL3;Q96M96 F8W1R0 FGD4 FYVE, RhoGEF and PH domain-containing protein 4 1 S(1)ADLPHSFK;S(1)ADLPHSFK 77.67399999999999 0.012872999999999999 3658600.0 60948.0 67574.0 68156.0 62165.0 63669.0 63598.0 60069.0 59802.0 77303.0 57092.0 True False 60078.87034350567 67417.53655473434 62552.476769768284 66736.82147636083 59924.11459807015 60878.061794179004 63179.07890012567 62580.619237934385 68596.32210332212 66960.27612969175 0.8972315201798473 1.0068288312335654 0.9341729213991556 0.9966628773618239 0.8949203626640722 0.9091668271538721 0.9435307401922526 0.9345932074223434 1.0244330828394674 1.0 16.03101785681219 -8.258694205333008 24.961882769666605 1.0122165464965227 0.9412201460701293 0.3949326963847487 0.03589134645173731 229.1145267684342 2083389.1793303525 0.026761926321885236 0.00902597982102212 5.511956667245901e-09 8.258694205333008 -0.07099640042639344 S(ph)ADNTLER ddPTM_PC-9_AZD4547_30min_R2 1 SADNTLER 8 0 Q96QZ7-7;Q96QZ7-6;Q96QZ7-2;Q96QZ7;A0A087WT53 Q96QZ7-7 MAGI1 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 1 S(1)ADNTLER 101.39 0.0045996000000000006 6011400.0 7287.8 8132.4 3704.3 11434.0 11652.0 8577.6 8612.7 11426.0 12924.0 8476.0 True False 9605.168804343097 10761.039262250279 3655.178561653379 8798.067953539028 10034.320928160376 8041.2413160274555 9379.213614989281 9660.374243359614 13607.136255131067 8179.257819893612 1.1743325636442687 1.3156498424682557 0.44688389119649025 1.075656024944017 1.2268009089718233 0.9831260357717944 1.1467071733791219 1.18108200720408 1.663615031431795 1.0 12.997754224633935 -7.807173640668132 2.6016197069666673 1.345578704258921 1.037748494329479 0.14286446884308612 0.2684493085142763 0.5006626337818566 6.738869980510713 0.1774490865231135 0.07548492147881754 1.5589290834173804e-08 7.807173640668132 -0.3078302099294419 S(ph)ADNTLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SADNTLER 8 0 Q96QZ7-7;Q96QZ7-6;Q96QZ7-2;Q96QZ7;A0A087WT53 Q96QZ7-7 MAGI1 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 1 S(1)ADNTLER 81.525 0.041267 0.0 7941.5 10270.0 16799.0 15444.0 17775.0 11009.0 9840.1 9682.9 10691.0 7969.9 True False 9285.839098225313 11289.537727934512 17199.55187056228 14578.722750123557 14292.116348905143 10431.668659763118 8907.974491845356 9428.7341348806 10847.335649615103 9414.779780306317 0.9863044399242646 1.1991292405532186 1.8268671463287993 1.5484932298277536 1.5180510519004555 1.1080098423102698 0.9461691828925104 1.0014821753561856 1.1521603163045175 1.0 13.200711634034176 -6.8591928550300985 5.069324250499828 1.0262432952194076 1.4331164752984524 0.4363481950653487 0.21335610125222773 0.21563170473811413 8.990421810638338 0.08338016943274769 0.07374914560503118 1.3829521218004388e-07 6.8591928550300985 0.4068731800790448 S(ph)ADVSPTTEGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SADVSPTTEGVK 12 0 A0A0J9YX34;Q9C040;Q9C040-2 A0A0J9YX34 TRIM2 Tripartite motif-containing protein 2 1 S(1)ADVSPTTEGVK 103.46 0.0051496 0.0 6885.8 6053.3 6465.9 7778.9 11186.0 6699.2 7827.9 5996.5 5986.8 5520.3 True False 8051.42993925075 6654.231619133985 6620.071578062304 7343.073452534071 8994.183599372878 6347.882158732407 7086.384642911786 5839.098228816933 6074.345624087148 6521.086691329241 1.2346761085014142 1.0204175981867838 1.0151792011697496 1.1260505802350065 1.3792461326011796 0.9734393145199043 1.0866876915367791 0.8954179732928389 0.9314928495221353 1.0 12.67089668371295 -7.400193018145581 1.86568231734583 0.9410796027777185 1.132216839206725 0.3377951898753495 0.1137467595342998 0.4310414342759462 2.926714986668756 0.06696900590406508 0.037401150075635554 3.979302748348143e-08 7.400193018145581 0.19113723642900637 S(ph)AEEGELAESK ddPTM_PC-9_AZD4547_30min_R2 2 SAEEGELAESK 11 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 S(1)AEEGELAESK;S(1)AEEGELAESK 126.32 0.00041668 164801000.0 60600.0 73703.0 72346.0 73309.0 75327.0 75253.0 77928.0 88644.0 76883.0 80659.0 True False 79869.53944169592 97526.05340928037 71386.64476996327 56408.74266275952 64869.14628866605 70547.41801378166 84863.44103346029 74946.10663647544 80946.87842024465 77835.15296068892 1.0261371167605269 1.2529820999842636 0.9171517245686854 0.7247206502086412 0.8334170849696739 0.906369620027753 1.0902970933495955 0.9628824995606726 1.0399784074571978 1.0 16.24813425131667 -5.280457936957841 24.38862979773911 0.926504918496079 1.1395596011431384 0.35403662559102267 0.11046875027801907 579.3920776854777 742988.3773791342 0.0313425480976644 0.06542249351816039 5.242543745432768e-06 5.280457936957841 0.2130546826470594 S(ph)AEEGELAESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SAEEGELAESK 11 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 S(1)AEEGELAESK;S(1)AEEGELAESK 159.08 0.00066113 107848000.0 42375.3 68592.0 49723.0 52575.8 59678.0 46692.0 64111.0 46227.0 40717.0 37758.2 True False 49548.60133967477 75401.3604512644 50908.58489552761 49630.14837904343 47984.52430210752 44243.3893234317 58037.941956555034 45013.590231555136 41312.40909600394 44603.462766253244 1.1108689385695631 1.690482213150336 1.141359476108765 1.1126972055764548 1.0758026692585037 0.9919272311948396 1.3011981213365849 1.009194969176523 0.9262152876449024 1.0 15.444868096909747 -5.495024560605857 20.877580543482484 1.0724338724486662 1.4044878324486405 0.4097254959201694 0.1609588228878911 81.38413224982372 60998.13722096009 0.03981285101669829 0.08229990419300165 3.198714208059689e-06 5.495024560605857 0.33205395999997434 S(ph)AEEGELAESK ddPTM_PC-9_Lapatinib_30min_R1 2 SAEEGELAESK 11 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 S(1)AEEGELAESK;S(1)AEEGELAESK 184.96 0.0011801 152531000.0 36747.0 48982.0 51016.0 48580.0 57092.0 56512.0 72068.0 67293.0 55289.0 53693.0 True False 36222.98104142554 48868.585188445126 46821.66140745491 52152.735258129316 53733.96080719064 54095.113495906204 75799.32840856779 70419.67844517433 49061.77060101906 62973.76350857465 0.5752074994929172 0.7760150015774596 0.743510611384685 0.8281660861991849 0.8532753612522158 0.8590103319542033 1.2036652120727511 1.1182383666109748 0.7790827142535113 1.0 15.942463269433768 -6.219300307993178 0.8347638877717503 1.0251171329891784 0.6646857859676295 0.5459038745644325 0.1190048714331525 0.5250910110017102 0.7801883071508509 0.06444501250083745 0.11417631220140524 6.035311524905836e-07 6.219300307993178 -0.3604313470215489 S(ph)AEPSPTVMSTSLGSNLSELDR ddPTM_PC-9_AZD4547_30min_R2 2 SAEPSPTVMSTSLGSNLSELDR 22 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 S(0.993)AEPS(0.007)PTVMSTSLGSNLSELDR;S(0.756)AEPS(0.244)PTVMSTSLGSNLSELDR 164.56 2.0980000000000003e-24 5130300.0 6274.7 9457.8 18389.9 15406.5 11808.3 12439.400000000001 11486.099999999999 15703.3 11038.6 12179.599999999999 True False 8269.924078132166 12514.848892640635 18146.037910252802 11854.76945305221 10168.921371094768 11661.562351542612 12508.340648475905 13276.715810935493 11622.077860251453 11753.195911181716 0.70363194322868 1.0648039041648494 1.5439237163560837 1.0086422061401918 0.8652047875267946 0.9922035197633415 1.064250161658223 1.1296260107690654 0.9888440512758304 1.0 13.520765485129976 -5.9240883350383 24.020002321801915 1.0080865037808264 1.1295337912701529 0.043151298768646984 0.19908094302132365 81.57798180503606 25808.315936054703 0.05871456722067508 0.08708776389320075 1.1909997353026695e-06 5.9240883350383 0.12144728748932643 S(ph)AEPSPTVMSTSLGSNLSELDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAEPSPTVMSTSLGSNLSELDR 22 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 S(0.918)AEPS(0.067)PT(0.015)VMSTSLGSNLSELDR 71.001 0.024832 0.0 1312.7 1248.3 3055.7 3512.7 3119.3 3091.6 2858.6 1568.5 3222.6 1191.4 True False 1534.914182993183 1372.2229742727036 3128.5594768067836 3315.8948073270535 2508.095557082408 2929.4710535492472 2587.8127135282275 1527.3285369631215 3269.7244284397752 1407.39138888279 1.0906093323560995 0.9750116315277418 2.2229491394645273 2.3560573366583295 1.782088178806732 2.0814899655416457 1.8387299609545538 1.085219469884308 2.3232516940687944 1.0 10.458807875695003 -5.2481990741146065 24.806369612343396 1.8647479324674374 1.032810315919904 0.3395032494950564 0.44682665506608377 754.239354886527 1413098.190082627 0.11139620172973422 0.29085559303140623 5.6467807546932915e-06 5.2481990741146065 -0.8319376165475334 S(ph)AEPSPTVMSTSLGSNLSELDR ddPTM_PC-9_Lapatinib_30min_R1 3 SAEPSPTVMSTSLGSNLSELDR 22 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 S(0.96)AEPS(0.033)PT(0.007)VMSTSLGSNLSELDR;S(0.941)AEPS(0.056)PT(0.003)VMSTSLGSNLSELDR;S(0.762)AEPS(0.237)PT(0.001)VMSTSLGSNLSELDR 126.09 2.2721000000000002e-06 13762600.0 21228.6 12755.0 21181.0 22771.9 22312.4 21673.3 20778.0 18113.1 21749.6 18118.5 True False 20925.87627115154 12725.466581164865 19439.579941024418 24446.62149083151 21000.028499866195 20746.383481929926 21853.783172465184 18954.70075112252 19299.931014558486 21250.25858361629 0.9847351357543082 0.5988381991255417 0.9147926301476687 1.1504152476374843 0.9882246099375459 0.9762885190453707 1.0284008115230279 0.8919750635757618 0.9082209959288926 1.0 14.375192776330664 -5.5134883167787825 24.97710284349372 0.9915643361595287 0.7830438327579474 0.34776277002277667 0.10880323318709952 415.22756178140287 1104440.0005550277 0.02807596364238942 0.05240137523995929 3.065573147172864e-06 5.5134883167787825 -0.20852050340158124 S(ph)AESPTSPVTSETGSTFKK ddPTM_PC-9_AZD4547_30min_R2 1 SAESPTSPVTSETGSTFKK 19 1 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 S(0.475)AES(0.379)PT(0.123)S(0.023)PVTSETGSTFKK 62.684 0.0067337000000000004 7968600.0 5145.5 4622.7 4620.3 8085.0 6087.3 6048.7 4286.9 6581.3 4337.8 8124.4 True False 6781.661966951262 6116.897373174508 4559.031803149607 6221.1281620048085 5242.183469446506 5670.473832803492 4668.425795174285 5564.311308228834 4567.087252205782 7839.967228874898 0.8650115196877536 0.7802197629915776 0.5815115892778887 0.7935145620369631 0.6686486456396583 0.7232777468659461 0.5954649629121274 0.7097365519252763 0.5825390743197274 1.0 12.936631908538478 -10.484020546688694 4.262367551449323 1.0000108981421616 0.6985925609725276 0.4944340028066342 0.09100016961672708 92598790.78029846 168723040.436354 14755.402809884014 0.02326604657819532 3.2807977112823005e-11 10.484020546688694 -0.30141833716963395 S(ph)AFSSLQNIPESLRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAFSSLQNIPESLRR 15 1 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 S(0.691)AFS(0.154)S(0.154)LQNIPESLRR 69.422 0.011821 5207800.0 64068.0 73547.0 74545.0 78387.0 90901.0 81888.0 72835.0 81048.0 86570.0 67006.0 True False 74913.44699931984 80848.2601048103 76322.435513487 73995.23052408296 73089.60158828845 77593.64912441472 65935.54152026477 78920.57587745444 87835.92247565032 79153.65738079592 0.9464306448775059 1.0214090261914481 0.9642313196762551 0.9348302147063581 0.9233888111659296 0.980291393878665 0.8330068843573348 0.9970553286979505 1.1096887418996368 1.0 16.27236839274491 -8.00172656493815 24.99998146902925 1.054353613121803 0.9451777797948732 0.4300091458019537 0.0515647250073698 56.635171887151124 820044.723974016 0.02864389645113897 0.013440548264648076 9.960323293987171e-09 8.00172656493815 -0.10917583332692982 S(ph)AGEEEDGPVLTDEQK ddPTM_PC-9_AZD4547_30min_R2 4 SAGEEEDGPVLTDEQK 16 0 Q66PJ3;F5GYV5;F8WCT1;Q66PJ3-2;H7BZV4;A0A0C4DG62;Q66PJ3-4;Q66PJ3-3;F5H7X4;Q66PJ3-7 Q66PJ3;H7BZV4;F5H7X4 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 S(1)AGEEEDGPVLTDEQK;S(1)AGEEEDGPVLTDEQK;S(1)AGEEEDGPVLTDEQK;S(1)AGEEEDGPVLTDEQK 320.78 8.442199999999998e-148 475281400.0 117357.0 144105.6 163465.0 205632.0 182822.0 179885.0 168845.0 171094.0 139757.0 159525.0 True False 154674.08482275758 190684.91706140072 161297.34729386625 158226.71938273005 157440.32103743008 168636.7625132438 183871.87790389394 144655.35364899112 147144.2697004296 153940.07830563068 1.0047681313742716 1.238695726026703 1.0477930703246008 1.0278461666661538 1.0227376961888381 1.095470161957658 1.194437991247718 0.9396861119025431 0.9558541954765752 1.0 17.232009360718315 -7.788426634084413 24.99997479646201 0.9608275086333418 1.0895304005435633 0.3844871616467236 0.07245015216636931 237.76069933378983 220249.2496532389 0.04004093769477413 0.01924330954518985 1.627696261204235e-08 7.788426634084413 0.12870289191022155 S(ph)AGEEEDGPVLTDEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SAGEEEDGPVLTDEQK 16 0 Q66PJ3;F5GYV5;F8WCT1;Q66PJ3-2;H7BZV4;A0A0C4DG62;Q66PJ3-4;Q66PJ3-3;F5H7X4;Q66PJ3-7 Q66PJ3;H7BZV4;F5H7X4 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 S(1)AGEEEDGPVLTDEQK;S(1)AGEEEDGPVLTDEQK;S(1)AGEEEDGPVLTDEQK;S(1)AGEEEDGPVLTDEQK 325.61 2.119199999999999e-167 356556000.0 122553.0 137554.0 113954.0 144255.0 159214.0 128623.0 153293.0 145024.0 130496.0 109032.0 True False 143298.80236791619 151209.45205728413 116671.09553295151 136172.86003101995 128017.15962726208 121877.7834521494 138771.97729478878 141217.27366562941 132404.25712582283 128798.63850316305 1.1125801020357606 1.173998838920729 0.9058410623656266 1.0572538779412315 0.9939325532864094 0.946266085329437 1.077433573114834 1.0964189940731508 1.0279942293223172 1.0 16.974757817616698 -5.234972546919414 24.99329938875057 1.01738306815541 1.14328949670719 0.4588490665881373 0.05638484169510576 696.7465090570774 657953.282884804 0.014684814821027863 0.038827112335096434 5.8214001545611155e-06 5.234972546919414 0.12590642855178014 S(ph)AGEEEDGPVLTDEQK ddPTM_PC-9_Lapatinib_30min_R1 4 SAGEEEDGPVLTDEQK 16 0 Q66PJ3;F5GYV5;F8WCT1;Q66PJ3-2;H7BZV4;A0A0C4DG62;Q66PJ3-4;Q66PJ3-3;F5H7X4;Q66PJ3-7 Q66PJ3;H7BZV4;F5H7X4 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 S(1)AGEEEDGPVLTDEQK;S(1)AGEEEDGPVLTDEQK;S(1)AGEEEDGPVLTDEQK;S(1)AGEEEDGPVLTDEQK 349.54 1.4073999999999994e-213 437591000.0 210310.0 164837.0 172251.0 167184.0 188463.0 167019.0 176391.0 166075.0 171668.0 168777.0 True False 207310.94083386936 164455.3300540555 158089.1876880884 179479.26906947457 177377.97687251397 159875.98671030498 185523.66289220858 173791.45078659523 152332.9420958192 197949.87956878368 1.0472900578948465 0.8307927764962874 0.798632401456731 0.9066904686199067 0.8960751946852215 0.8076589238578001 0.9372254395726609 0.8779568402122019 0.7695530930741814 1.0 17.594775664080288 -4.754706834948818 24.992157543386472 0.86556233111392 1.0472903676177185 0.39051316562254534 0.06651646071141826 229.428707799605 851595.0511833001 0.015740273252847894 0.1498484411226527 1.7591106788907637e-05 4.754706834948818 0.18172803650379854 S(ph)AGNIPLSPLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SAGNIPLSPLAR 12 0 H7C1I9;O15021-2;O15021-3;O15021-6;O15021 H7C1I9 MAST4 Microtubule-associated serine/threonine-protein kinase 4 1 S(1)AGNIPLSPLAR;S(1)AGNIPLSPLAR 143.05 8.329700000000001e-05 8560900.0 36234.0 31122.0 29139.0 31925.0 41162.0 31439.0 31616.0 26839.0 26791.0 24909.4 True False 42367.7005458787 34211.58648186738 29833.784270272892 30136.345752246496 33096.601583889395 29790.283494803578 28621.10359998198 26134.504688271114 27182.76769140757 29425.277037298114 1.4398403281700756 1.162659792072726 1.0138828678641487 1.0241652343339729 1.1247677138923002 1.0124045206793737 0.9726706587572038 0.8881651192321565 0.9237896947223966 1.0 14.844768377768297 -1.5228787452812627 0.6943718036262236 0.9743586855049232 56.553894544673255 0.8532885053305115 0.05730789034413407 111.34411165074013 0.604550882092241 0.02591896536789142 9598.230763016642 0.029999999999936095 1.5228787452812627 55.57953585916833 S(ph)AGNIPLSPLAR ddPTM_PC-9_Lapatinib_30min_R1 2 SAGNIPLSPLAR 12 0 H7C1I9;O15021-2;O15021-3;O15021-6;O15021 H7C1I9 MAST4 Microtubule-associated serine/threonine-protein kinase 4 1 S(1)AGNIPLSPLAR;S(0.999)AGNIPLS(0.001)PLAR 125.33 0.00029613 9061800.0 12034.7 14768.1 17321.7 12249.8 15661.2 15063.6 13754.400000000001 14750.599999999999 14376.0 18329.7 True False 11863.08297110632 14733.90537179936 15897.576689695623 13150.691156134873 14740.03900710387 14419.364942966671 14466.535531203936 15435.966725712766 12756.823494008759 21497.96422221 0.5518235516854344 0.6853628194514089 0.7394921921616885 0.6117179757210972 0.6856481318298792 0.6707316466770245 0.6729258352871502 0.7180199281272197 0.5933968147937196 1.0 14.391912427941886 -11.534007444898961 2.545738655181624 1.3587705225620372 0.6638604467307672 0.7772881206792741 0.05473215602769924 15071527.710356597 6096181.238971317 31641267.01709996 0.013012964446627725 2.9241022509517635e-12 11.534007444898961 -0.6949100758312701 S(ph)AGTATQMR ddPTM_PC-9_AZD4547_30min_R2 1 SAGTATQMR 9 0 Q92934;F5H1R6 Q92934 BAD Bcl2-associated agonist of cell death 1 S(0.997)AGT(0.002)ATQMR 72.096 0.033208 2054000.0 11329.0 8451.7 11509.0 21138.0 14873.0 12996.0 10138.0 14100.0 10472.0 13346.0 True False 14931.386342161268 11183.546742998456 11356.383140152984 16264.960678844485 12808.140676667475 12183.358065553619 11040.26236009165 11921.168985766728 11025.528540988284 12878.760602206245 1.1593806891327252 0.8683713509732153 0.8817916172933237 1.262929033408553 0.9945165588739439 0.9460039239697104 0.8572457165016606 0.9256456699509211 0.8561016763600307 1.0 13.652706140774782 -6.810032731526976 3.4369069901328557 0.9043732376421987 1.0298878117425616 0.20649978610193986 0.11588504647769411 0.4116987966754819 9.951801566101167 0.04360485513932668 0.039466793897807106 1.548699893453765e-07 6.810032731526976 0.12551457410036293 S(ph)AGTATQMR ddPTM_PC-9_Lapatinib_30min_R1 1 SAGTATQMR 9 0 Q92934;F5H1R6 Q92934 BAD Bcl2-associated agonist of cell death 1 S(1)AGTATQMR 76.843 0.023925 9215800.0 18091.0 8401.7 14208.0 10610.0 13502.0 11863.0 12814.0 10834.0 15880.0 10464.0 True False 17833.019022516924 8382.246379848908 13039.873084466028 11390.294793922436 12707.838905953338 11355.647144003664 13477.44622061647 11337.38719146151 14091.427176186644 12272.688457596438 1.453065404872948 0.6830000133068269 1.0625115376732899 0.9281010296380638 1.0354568153392303 0.9252778788640111 1.0981657578274402 0.9237900261734417 1.1481939939137344 1.0 13.583163700236076 -8.263440332224937 24.913844928501835 1.074096972022498 1.0020206162438936 0.013494795993184816 0.18646470995925726 849.4094687911972 10575609.174275655 0.13806773907622666 0.0427933625750914 5.45204796301e-09 8.263440332224937 -0.07207635577860438 S(ph)AILVPSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAILVPSEK 9 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 S(1)AILVPSEK 84.507 0.028201999999999998 0.0 52278.0 56935.0 55213.0 49869.0 49250.0 36326.0 52632.0 29531.0 36607.0 28918.0 True False 61127.63286243441 62587.13052969346 56529.48731646857 47075.001607479426 39599.816044083156 34421.00061173177 47646.315937318155 28755.842540680893 37142.30812136002 34160.60448523795 1.7894189456995675 1.8321435312053584 1.6548151933580988 1.378049431994749 1.1592246870571534 1.0076227025375486 1.3947737944130314 0.8417837732674592 1.0872848616426145 1.0 15.060045883785929 -5.890178178474615 1.36357597812914 1.0686423451682987 1.8346538922692524 0.8467091360513681 0.13056489345661013 0.1579282630412311 0.5952864683166115 0.045195994462925396 0.09322635140880405 1.2877211285388635e-06 5.890178178474615 0.7660115471009536 S(ph)AKSEESLTSLHAVDGDSK ddPTM_PC-9_AZD4547_30min_R2 1 SAKSEESLTSLHAVDGDSK 19 1 A7KAX9;A7KAX9-2;G3V174 A7KAX9 ARHGAP32 Rho GTPase-activating protein 32 1 S(0.289)AKS(0.289)EES(0.136)LT(0.282)S(0.005)LHAVDGDSK 74.408 0.0020569000000000004 9549000.0 15370.0 15694.0 47809.0 66589.0 63242.0 54345.0 28454.0 50391.0 43233.0 60376.0 True False 20257.340284139707 20766.778587102937 47175.02142215431 51237.934839794485 54461.93993638161 50946.79855898058 30986.350877298068 42604.22881998378 45518.20811808118 58262.254617024184 0.3476923510306539 0.35643623343465497 0.8097012676946732 0.8794361834535459 0.9347722688450144 0.8744391869808273 0.5318426326097563 0.731249229883645 0.7812641034454715 1.0 15.830273911131771 -5.260011965340681 10.664344941162103 0.8064726577933269 0.351799853223944 0.7038442060843968 0.120673042526186 0.05741944210637566 219.70455597942555 0.0334800151722852 0.07860800828085245 5.4952573354737934e-06 5.260011965340681 -0.45467280456938286 S(ph)AMPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAMPLR 6 0 F5H385;Q9BRY0 F5H385 SLC39A3 Zinc transporter ZIP3 1 S(1)AMPLR 81.78399999999999 0.04193 3860800.0 12673.0 17416.0 19258.0 21152.0 24201.0 22574.0 23878.0 24739.0 23729.0 20230.0 True False 14818.288596840563 19144.945381665788 19717.183756371705 19966.92201570926 19458.987778332117 21390.17970074417 21616.10297825057 24089.627463137196 24075.991734142423 23897.538859408116 0.6200759284886282 0.8011262370697516 0.8250717311255396 0.8355221068235055 0.8142674395389211 0.89507877052047 0.9045326008431459 1.0080380077990105 1.0074674164475332 1.0 14.544574426284443 -3.239568855059514 0.22052404850154686 1.0417058906059304 9.895751013780427e-11 0.8586189854442985 0.04290098606771946 9.271637724804103 0.22716704306306432 0.07592242535762601 2.948092525396642 0.0005760114877897563 3.239568855059514 -1.041705890506973 S(ph)AMPLR ddPTM_PC-9_Lapatinib_30min_R1 2 SAMPLR 6 0 F5H385;Q9BRY0 F5H385 SLC39A3 Zinc transporter ZIP3 1 S(1)AMPLR;S(1)AMPLR 86.47200000000001 0.035719 2470900.0 19206.9 18043.3 19012.7 18014.9 21178.0 19310.2 19572.8 18437.2 23889.0 13964.900000000001 True False 18933.00608388592 18001.521847427055 17449.549197144384 19339.775841944695 19932.35167754998 18484.347760274773 20586.18381355409 19293.859620307736 21198.369257677754 16378.714357940415 1.1559519062439223 1.0990802729702591 1.0653796638613964 1.1807871740903007 1.2169668047166815 1.128559138178849 1.256886429768762 1.1779837659208006 1.2942633221636695 1.0 13.99953449707676 -5.855341218489624 7.2579794475157176 1.1900618227988007 1.1063437523745658 0.14586403147928872 0.07766822741016266 0.34848133792364727 23.062310415670087 0.020536834473251116 0.030670159207180237 1.3952716868044842e-06 5.855341218489624 -0.08371807042423485 S(ph)ANDELFR ddPTM_PC-9_AZD4547_30min_R2 1 SANDELFR 8 0 Q9ULV8-2;Q9ULV8 Q9ULV8-2 CBLC E3 ubiquitin-protein ligase CBL-C 1 S(1)ANDELFR 80.245 0.019571 1591900.0 8184.8 5964.5 4868.9 8296.2 6171.5 6271.9 5492.9 6594.4 5199.3 5139.5 True False 10787.39614558404 7892.407982845386 4804.335204717255 6383.6392650122825 5314.693752844303 5879.717101519374 5981.757458842717 5575.387004236886 5474.124383418678 4959.567669342051 2.1750678415514235 1.591349994402317 0.9687004039516635 1.2871362365863541 1.0716042419780845 1.1855301698705107 1.2061046158961417 1.1241679468760089 1.1037503162336908 1.0 12.275998649532166 -4.9149016049699705 2.6428017738134577 1.133240018522634 2.246115503606104 0.9217921127168889 0.09630329129883033 0.08266645132649898 0.9439570980301651 0.02367473460478933 0.18077716039157876 1.2164615745255677e-05 4.9149016049699705 1.1128754850834701 up S(ph)ANDELFR ddPTM_PC-9_Lapatinib_30min_R1 2 SANDELFR 8 0 Q9ULV8-2;Q9ULV8 Q9ULV8-2 CBLC E3 ubiquitin-protein ligase CBL-C 1 S(1)ANDELFR;S(1)ANDELFR 101.35 0.0046131 2194630.0 5442.799999999999 7214.8 6595.3 3851.1000000000004 4826.5 4846.5 5645.0 3895.6 6577.2 3736.2 True False 5365.184673912725 7198.094573875987 6053.059892594233 4134.322740892997 4542.614759264097 4639.226492743301 5937.270478802867 4076.6037975869863 5836.406475013525 4381.9971918264355 1.22436971979813 1.6426515715944103 1.3813472778770293 0.9434790940999652 1.0366539640274657 1.0587013842447606 1.3549233874173676 0.9303072592540481 1.33190557171053 1.0 12.09737284444906 -5.632169541783861 6.289842179490818 1.0988473242995422 1.4517095156435764 0.44155499713964397 0.16627716404515608 0.17372512460315778 8.942196971923005 0.04322551550174182 0.0755207121226452 2.3325472944787332e-06 5.632169541783861 0.3528621913440342 S(ph)APAS(ph)PTHPGLMSPR ddPTM_PC-9_Lapatinib_30min_R1 2 SAPASPTHPGLMSPR 15 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 2 S(1)APAS(0.758)PT(0.242)HPGLMSPR;S(0.999)APAS(0.999)PT(0.002)HPGLMSPR 92.95200000000001 0.011906 19131000.0 38492.0 35565.0 43812.0 30631.0 36262.0 32637.0 26763.0 24295.0 30246.0 21166.0 True False 37943.09702143173 35482.65142760709 40209.94647921073 32883.70592202055 34129.14045383502 31241.191590562914 28148.657187635265 25423.834393257996 26839.37697550007 24824.514898077796 1.528452708027327 1.4293391662752923 1.6197676629050366 1.324646465682469 1.3748160072395894 1.2584814534676758 1.1339056293025433 1.024142243972977 1.0811642074656729 1.0 14.59947790552161 -6.90240688215126 0.7704107241422917 1.007228267739119 1.5192714479990745 0.8967266892316016 0.06551349011925345 0.18741524867889658 0.23770117453981385 0.04639580405710608 0.03917077440260947 1.2519676808627365e-07 6.90240688215126 0.5120431802599554 S(ph)APASPT(ph)HPGLMSPR ddPTM_PC-9_Lapatinib_30min_R1 1 SAPASPTHPGLMSPR 15 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 2 S(0.606)APAS(0.505)PT(0.866)HPGLMS(0.023)PR 112.62 0.0079724 4491000.0 11372.0 6348.9 13302.0 12942.0 17329.0 26654.0 21378.0 18627.0 32449.0 28641.0 True False 11209.833194630608 6334.199512125249 12208.360907204895 13893.797853246395 16309.742290124837 25514.070553508707 22484.848236642636 19492.47842120669 28794.251916881632 33591.55868826639 0.33370982569338853 0.18856521577064536 0.36343538031384365 0.41360979947916293 0.4855309764420627 0.7595381563053467 0.6693600748123857 0.5802790695751626 0.8571871339492064 1.0 15.035811119440407 -6.506260595504238 0.26641115955460476 1.0254451694273998 1.2391896339709227e-15 0.8674798657343104 0.08832052280814669 1.263465475350257 0.1685252955887045 0.14964711736960895 0.4269127726212843 3.117018676591618e-07 6.506260595504238 -1.0254451694273985 down S(ph)APASPTHPGLMSPR ddPTM_PC-9_AZD4547_30min_R2 2 SAPASPTHPGLMSPR 15 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 S(1)APASPTHPGLMSPR;S(0.997)APAS(0.001)PT(0.002)HPGLMSPR 85.163 0.027016000000000002 0.0 5177.1 3619.6000000000004 19498.4 30027.0 21797.0 18668.800000000003 10190.8 24183.0 12603.5 19004.2 True False 6823.3101096304335 4789.564914864139 19239.838475971774 23104.73906252547 18770.862793607266 17501.43698478051 11097.761457804498 20446.07302005649 13269.695279444793 18338.86874242828 0.3720682123562082 0.2611701398888983 1.049128970068859 1.2598780975552222 1.0235561995260667 0.9543356916171001 0.6051497294448177 1.1149037221010827 0.7235830882383932 1.0 14.162617026659868 -5.260158793905153 24.99999991329645 0.9696225069476047 0.3166191181528261 0.681725920772335 0.17755747862097004 62.56269582181487 1221334.76611451 0.04774805527702058 0.1129440204074587 5.493399783971084e-06 5.260158793905153 -0.6530033887947786 S(ph)APELPEGILK ddPTM_PC-9_AZD4547_30min_R2 3 SAPELPEGILK 11 0 Q3KR16-3;Q3KR16-2;Q3KR16 Q3KR16-3 PLEKHG6 Pleckstrin homology domain-containing family G member 6 1 S(1)APELPEGILK;S(1)APELPEGILK;S(1)APELPEGILK 136.01 7.726e-05 17205100.0 41476.0 41697.0 84221.0 139261.0 131827.0 97546.0 73011.0 97265.0 70004.0 98243.0 True False 54664.50524560694 55174.73982072326 83104.17451097621 107156.52801100223 113525.09654965633 91446.43319963805 79508.83755895165 82234.92917734753 73704.26852400151 94803.54247284183 0.5766082555540217 0.5819902756959642 0.8765935569842539 1.130300885557089 1.1974773683396653 0.9645887781654838 0.8386694788512611 0.8674246450327021 0.7774421356155063 1.0 16.532653348087706 -5.327259831677933 3.779038374114861 0.9683222276205039 0.5730717225990561 0.6174749985158998 0.12028524745460753 0.16096320094652541 4.522030616128875 0.036916573156005286 0.08827799834956443 4.706956322150121e-06 5.327259831677933 -0.39525050502144776 S(ph)APELPEGILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SAPELPEGILK 11 0 Q3KR16-3;Q3KR16-2;Q3KR16 Q3KR16-3 PLEKHG6 Pleckstrin homology domain-containing family G member 6 1 S(1)APELPEGILK;S(1)APELPEGILK;S(1)APELPEGILK;S(1)APELPEGILK 136.93 6.2859e-05 20654700.0 51716.2 54500.8 80201.0 96366.0 107092.0 107125.0 97325.0 76090.0 93173.0 79569.0 True False 60470.73121849019 59911.2792407608 82113.2960039863 90966.92544278731 86108.09136635438 101507.1764172154 88105.67142801879 74092.71812401911 94535.4788590019 93994.22983214248 0.6433451428505825 0.6373931607052054 0.873599327859024 0.9677926571156399 0.9160997597419396 1.0799298701472395 0.9373519160203808 0.788268793268863 1.0057583218440749 1.0 16.520284574126265 -5.347830445025878 3.0451502131103423 0.9495702203014068 0.632328409794288 0.7520394297356041 0.07139396998543618 0.12670510296881157 2.2460150720104397 0.02007936216586274 0.05156089447049591 4.489206209591483e-06 5.347830445025878 -0.31724181050711886 S(ph)APELPEGILK ddPTM_PC-9_Lapatinib_30min_R1 2 SAPELPEGILK 11 0 Q3KR16-3;Q3KR16-2;Q3KR16 Q3KR16-3 PLEKHG6 Pleckstrin homology domain-containing family G member 6 1 S(1)APELPEGILK;S(1)APELPEGILK 125.82 0.00044194 4904200.0 27539.0 23442.0 28337.0 26878.0 28524.0 26413.0 24069.0 21344.0 30353.0 17894.1 True False 27146.28880996592 23387.721489272182 26007.24124398324 28854.697782379575 26846.274400341677 25283.377561710273 25315.175049478505 22335.720160102854 26934.325508740127 20987.071342610507 1.2934767489378196 1.1143870961065245 1.239202974984898 1.374879672886767 1.2791815476338093 1.2047120414736896 1.2062271403290346 1.064260934528495 1.283377040514213 1.0 14.357213238209999 -7.374546501697123 1.9390379417758996 1.1299616111892166 1.2548276271702343 0.2952017152584131 0.09178800936305809 0.5020455439645963 3.682114830643718 0.050888063673869825 0.02932451469054306 4.2213707667745215e-08 7.374546501697123 0.12486601598101776 S(ph)APPNLWAAQR ddPTM_PC-9_AZD4547_30min_R2 2 SAPPNLWAAQR 11 0 Q92934;F5H1R6;F5H3B1 Q92934 BAD Bcl2-associated agonist of cell death 1 S(1)APPNLWAAQR;S(1)APPNLWAAQR 105.66 0.0025308 68521000.0 15450.1 9696.5 17590.7 15027.2 12990.5 13437.3 27934.0 27786.0 14942.3 15459.099999999999 True False 20362.91041795622 12830.703999607713 17357.43582444081 11562.911207925632 11186.99330735216 12597.063506791606 30420.071884671557 23492.31215875987 15732.119472689945 14917.881614383823 1.3650001350273688 0.8600888739615916 1.1635322140983322 0.7751041003554199 0.7499049527625732 0.844427099799848 2.039168339782273 1.5747753445173194 1.0545813326150164 1.0 13.864755062501398 -7.208300501237998 24.999957725855456 1.4650314235308644 0.9464908388382627 0.3222998448851969 0.32164573897759463 345.8533829304968 162711.79762748966 0.12260082036408318 0.09496613705570182 6.190126136671499e-08 7.208300501237998 -0.5185405846926017 S(ph)APPNLWAAQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SAPPNLWAAQR 11 0 Q92934;F5H1R6;F5H3B1 Q92934 BAD Bcl2-associated agonist of cell death 1 S(1)APPNLWAAQR;S(1)APPNLWAAQR;S(1)APPNLWAAQR;S(1)APPNLWAAQR 115.92 0.0013119000000000002 46605200.0 11494.9 20541.199999999997 17298.5 28803.5 20324.9 23449.0 31731.4 21392.8 12083.3 11112.7 True False 13440.75953537621 22580.3945839385 17710.961844926576 27189.733277206935 16342.381748515449 22219.293160394715 28725.57207655834 20831.261667545234 12259.99540314229 13127.344541915203 1.0238749727685048 1.7201037507501995 1.3491656129216405 2.071228738637198 1.2449114667734005 1.6925961750641345 2.188224129018514 1.586860282445674 0.9339280586409922 1.0 13.680287490474715 -8.246792930148697 7.256364328061712 0.9645742276509515 1.6307272533402406 0.37060474358188156 0.33418691610459816 0.14588296975904486 47.336919975486026 0.24556312540670924 0.08390085773356334 5.6650933401265346e-09 8.246792930148697 0.6661530256892891 S(ph)APPNLWAAQR ddPTM_PC-9_Lapatinib_30min_R1 2 SAPPNLWAAQR 11 0 Q92934;F5H1R6;F5H3B1 Q92934 BAD Bcl2-associated agonist of cell death 1 S(1)APPNLWAAQR;S(1)APPNLWAAQR 104.59 0.0026634000000000002 48011000.0 11617.400000000001 16391.2 18368.0 9802.6 13591.0 18748.5 18223.5 16264.8 20029.8 13004.7 True False 11451.73374562977 16353.247183472316 16857.85394253041 10523.51590451499 12791.604100934073 17946.67035988812 19167.023661729694 17020.52198557163 17773.833000855357 15252.54506732649 0.7508080582670301 1.0721651443275335 1.1052485908494551 0.689951470922589 0.8386537488970176 1.176634475142965 1.2566442896660357 1.1159135678957897 1.1653027689739393 1.0 13.896762373022067 -6.7675102344353695 24.96082377990563 1.1572527418491283 0.9021025613094238 0.4667541896573896 0.1337422829171655 137.25049365403586 564312.9661417666 0.048599707248564286 0.04395165191917426 1.7080074692650182e-07 6.7675102344353695 -0.2551501805397045 S(ph)APTS(ph)PTATNISSK ddPTM_PC-9_Lapatinib_30min_R1 1 SAPTSPTATNISSK 14 0 Q9H792;H0YN99;H3BUZ5 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 2 S(0.999)APT(0.154)S(0.755)PT(0.054)AT(0.036)NIS(0.001)SK 95.428 0.032763 0.0 12570.0 10158.0 13084.0 9071.7 10948.0 8633.5 8627.5 9823.4 9551.8 7783.7 True False 12390.749494944313 10134.479775105661 12008.284025700563 9738.86308030407 10304.060164596154 8264.265330671471 9074.189735318285 10279.831026084823 8475.975699086866 9129.10217387169 1.3572801858224077 1.1101288584666575 1.3153849959166137 1.066793085981398 1.128704659926723 0.9052659476552405 0.9939849026215777 1.1260506050098358 0.9284566584593467 1.0 13.156257266120745 -6.053530243937084 1.506850123080716 1.0038482009281002 1.2513956416922898 0.5877073694713528 0.09157924817755496 0.2879538972994522 1.3170068133785828 0.030838162494131675 0.051002604116672984 8.840356034904296e-07 6.053530243937084 0.24754744076418955 S(ph)APTSPCDQEIK ddPTM_PC-9_Lapatinib_30min_R1 2 SAPTSPCDQEIK 12 0 Q02156;E9PBI2 Q02156 PRKCE Protein kinase C epsilon type 1 S(0.671)APT(0.164)S(0.164)PCDQEIK;S(0.997)APT(0.003)S(0.001)PCDQEIK 106.58 0.0016545000000000002 7187200.0 21234.0 33943.0 23659.0 24180.0 31930.0 31411.0 25832.0 31413.0 27711.0 24544.1 True False 20931.19926616132 33864.40706895169 21713.848346381055 25958.2778621154 30051.9401767953 30067.624752617317 27169.454563053256 32872.56265879454 24589.895370233495 28786.514982042478 0.7271182107045108 1.1763982923975649 0.7543062562427764 0.9017513192655874 1.0439589577113526 1.0445038161574618 0.9438257663354536 1.1419431174388774 0.8542157807422363 1.0 14.81310552022374 -6.249021368015553 22.505454558412605 1.0107807474374024 0.9006732999375169 0.14955551670226985 0.13271153213227246 406.3307328565957 736398.4121239709 0.03706687534253117 0.04740390991953629 5.636099245919308e-07 6.249021368015553 -0.11010744749988555 S(ph)APY(ph)KGS(ph)EIR ddPTM_PC-9_Lapatinib_30min_R1 1 SAPYKGSEIR 10 1 Q96S94;Q96S94-3;A0A0A0MSF3 Q96S94 CCNL2 Cyclin-L2 3 S(1)APY(1)KGS(1)EIR 92.781 0.022484 1320800.0 2604.4 2988.0 2988.0 3582.9 3523.4 3303.0 3106.1 2805.1 2701.6 2832.5 True False 2567.2607784115344 2981.0814695821737 2742.3381740135505 3846.398418204023 3316.160539270924 3161.7383896690662 3266.9186597359776 2935.435186521015 2397.317358890796 3322.093850930993 0.7727839409750805 0.8973501662954967 0.8254848589677952 1.157823526606901 0.9982139843344864 0.9517306047157613 0.9833914411600524 0.8836099515064514 0.721628426668008 1.0 11.697877115445872 -5.004606999300632 1.698856167892901 0.9501864707582479 0.7678876064026922 0.17844788809803358 0.10947909940266155 1.134110451633828 4.5044974835097396 0.032488819122979434 0.29505549589330865 9.894480585764867e-06 5.004606999300632 -0.18229886435555576 S(ph)AS(ph)PPQKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASPPQKR 8 1 U3KQ90;P55199 U3KQ90 ELL RNA polymerase II elongation factor ELL 2 S(1)AS(1)PPQKR 62.464 0.041229 0.0 6218.5 4312.6 5475.0 5393.2 6498.4 4589.2 5606.3 6164.6 5607.9 3630.8 True False 7271.169229026516 4740.726427019513 5605.544764053129 5091.036488990311 5225.085169154726 4348.534273175122 5075.230677902926 6002.785781933608 5689.904928395521 4289.035298603012 1.6952924662090842 1.10531298927841 1.3069476872524037 1.186988712974342 1.2182425196772328 1.013872344345473 1.1833035460342298 1.3995654882786308 1.3266164841890642 1.0 12.066437474011625 -4.754353533387998 24.996636522745764 1.2041084193384952 1.6952933183814414 0.5970037707370824 0.12341957907806528 181.47506892239096 640131.634838341 0.031316818335948966 0.30768181442724746 1.7605423098205764e-05 4.754353533387998 0.49118489904294615 S(ph)ASADNLTLPR ddPTM_PC-9_AZD4547_30min_R2 1 SASADNLTLPR 11 0 Q8ND76-3;Q8ND76-2;Q8ND76 Q8ND76-3 CCNY Cyclin-Y 1 S(0.993)AS(0.007)ADNLTLPR 94.54700000000001 0.0065881 54902000.0 53540.0 58918.0 59110.0 73123.0 66871.0 60235.0 65161.0 67963.0 52637.0 63944.0 True False 70564.60629881851 77962.0912957136 58326.162778212085 56265.622089088145 57587.11592748133 56468.495927871845 70960.20276641664 57460.87998437336 55419.2843594347 61705.34002303883 1.1435737372563204 1.2634577698883924 0.9452368750651878 0.911843643809115 0.9332598427620709 0.9151314279572609 1.149984794507612 0.931214056399645 0.8981278498545326 1.0 15.913107726159003 -5.267916554176075 24.90753729156312 0.9605653228646492 1.2035157592383134 0.6327421508109337 0.07402665492560195 276.560191884005 1063497.0340842386 0.019829746803868422 0.04291178941205479 5.3961429464464495e-06 5.267916554176075 0.2429504363736642 S(ph)ASADNLTLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SASADNLTLPR 11 0 Q8ND76-3;Q8ND76-2;Q8ND76 Q8ND76-3 CCNY Cyclin-Y 1 S(0.604)AS(0.396)ADNLTLPR;S(0.834)AS(0.166)ADNLTLPR 115.37 0.0013659 53944000.0 87902.0 80274.0 78073.0 84641.0 116003.0 77682.0 85955.0 81207.0 83702.0 78332.0 True False 102782.07245636216 88243.07220761571 79934.55641350121 79898.83917982453 93273.04488450295 73608.2191686546 77812.72013969053 79075.40229592886 84925.98340137333 92532.97152422904 1.1107616103028688 0.9536392353347255 0.8638494484376411 0.8634634537690561 1.0079979422262488 0.7954809832231623 0.8409188514962569 0.8545646053874275 0.9177915936606026 1.0 16.497679900624398 -4.80707958420449 2.5963876508555708 0.8857882806025434 1.1503272018543833 0.508320208090292 0.06428613030113126 0.355304721178708 3.2756130874624927 0.016420414077270087 0.20413546050207057 1.55926674194558e-05 4.80707958420449 0.26453892125183986 S(ph)ASADNLTLPR ddPTM_PC-9_Lapatinib_30min_R1 3 SASADNLTLPR 11 0 Q8ND76-3;Q8ND76-2;Q8ND76 Q8ND76-3 CCNY Cyclin-Y 1 S(0.966)AS(0.034)ADNLTLPR;S(0.957)AS(0.043)ADNLTLPR;S(0.838)AS(0.162)ADNLTLPR 122.46 0.0017504999999999999 55042000.0 122346.0 108290.0 101084.0 89768.0 110733.0 88771.0 86046.0 75048.0 102517.0 74213.0 True False 120601.32360449119 108039.26115831794 92773.26371552379 96369.83817726941 104219.90264945438 84974.47126530818 90501.04085368846 78535.00405619387 90970.45590813125 87040.61816739319 1.3855752192907838 1.2412510783246158 1.0658617283382088 1.107182373083962 1.1973708923921318 0.9762622675988873 1.039756412111416 0.902279943659848 1.0451494695635128 1.0 16.409401182275865 -1.5228787452804902 0.3792175826458589 0.9849305225029779 6.614465461751282 0.7569279837266719 0.06671149779809686 33.487696764362106 0.4576023602742702 0.0529841311893902 138.44002974579314 0.02999999999998946 1.5228787452804902 5.629534939248304 S(ph)ASAPAS(ph)PREMIS(ph)LK ddPTM_PC-9_AZD4547_30min_R2 1 SASAPASPREMISLK 15 1 D6R9A8;B4DRK2;E9PHB5;E7EPC8;Q9UQB3-2;Q9UQB3 D6R9A8 CTNND2 Catenin delta-2 3 S(0.793)AS(0.232)APAS(0.975)PREMIS(1)LK 59.513000000000005 0.027036 5201900.0 0.0 0.0 0.0 1000.7 1033.2 0.0 0.0 1022.0 900.14 0.0 True False 0.0 0.0 0.0 770.0040756608803 889.7580143301842 0.0 0.0 864.0733832236589 947.7195627277684 0.0 0.0 S(ph)ASAPTLAETEKETAEHLDLAGASSR ddPTM_PC-9_Lapatinib_30min_R1 1 SASAPTLAETEKETAEHLDLAGASSR 26 1 Q86W92-2 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.483)AS(0.483)APT(0.034)LAETEKETAEHLDLAGASSR 84.948 5.7301e-07 6334500.0 6822.2 12843.0 9968.9 9385.5 13086.0 11376.0 13958.0 9038.2 13362.0 11414.0 True False 6724.914176961747 12813.262822571562 9149.29552306683 10075.740979110187 12316.307208065875 10889.47499875123 14680.676942981472 9458.147767571289 11857.030851902127 13386.894691801008 0.5023505698510138 0.9571497436533377 0.6834516692411456 0.7526570732853539 0.9200271976150802 0.8134429417317103 1.0966454342822956 0.7065229080620216 0.8857192892661009 1.0 13.708533722414444 -6.217113250814167 6.179760062339486 0.8941943593583589 0.7364996326960904 0.2754802692870817 0.14183888614111542 0.32849736380232536 33.186769330356405 0.04039294718581737 0.051809825269166436 6.065781318038909e-07 6.217113250814167 -0.15769472666226847 S(ph)ASASHQADIK ddPTM_PC-9_AZD4547_30min_R2 1 SASASHQADIK 11 0 C9JXK0;A0A494C1L1;Q14739 C9JXK0 LBR Lamin-B receptor 1 S(0.658)AS(0.323)AS(0.019)HQADIK 100.73 0.0040278 59229000.0 6375.5 12134.0 22116.0 23165.0 20184.0 11443.0 14880.0 19181.0 10260.0 11052.0 True False 8402.776381361928 16056.078206697262 21822.727389662316 17824.667145682302 17381.800001200572 10727.467401056496 16204.291173620424 16217.017185531304 10802.322653794865 10665.072843966995 0.7878780111769419 1.5054822823624543 2.046186435754817 1.671312273855245 1.6297872743581951 1.005850363893651 1.5193793245197427 1.520572566431642 1.0128690925824768 1.0 13.380606199074258 -6.735206709331258 24.990664024216123 1.2634977239190313 1.5636067402628822 0.16297705209158142 0.34412033455450763 456.54350013437926 434926.95894183026 0.11817212573203804 0.11813695680868068 1.8398960653794795e-07 6.735206709331258 0.3001090163438509 S(ph)ASASHQADIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SASASHQADIK 11 0 C9JXK0;A0A494C1L1;Q14739 C9JXK0 LBR Lamin-B receptor 1 S(0.333)AS(0.333)AS(0.333)HQADIK;S(0.626)AS(0.184)AS(0.19)HQADIK;S(0.409)AS(0.409)AS(0.181)HQADIK 78.529 0.010365000000000001 194037000.0 213301.0 241712.0 246703.0 225446.0 406780.0 206199.0 219606.0 201845.0 181984.0 166881.0 True False 249408.64641321628 265707.5699410424 252585.3351463375 212814.99152579403 327074.37909466313 195385.5614474061 198803.32987024414 196546.78262245576 184645.17172009658 197135.20427073067 1.265165434737355 1.3478443432972003 1.2812796987769661 1.0795382403313916 1.6591373433508292 0.9911246556402897 1.0084618351434713 0.9970151366395887 0.936642302947163 1.0 17.588825909324534 -6.923245024355312 24.999999362040153 0.9873411477572398 1.3128936846037704 0.6126067410693783 0.13494766052664528 24.23754157810397 7893.430729297847 0.04560856608038273 0.04022297274597976 1.1933146589918936e-07 6.923245024355312 0.3255525368465306 S(ph)ASASHQADIK ddPTM_PC-9_Lapatinib_30min_R1 3 SASASHQADIK 11 0 C9JXK0;A0A494C1L1;Q14739 C9JXK0 LBR Lamin-B receptor 1 S(0.5)AS(0.5)ASHQADIK;S(0.736)AS(0.206)AS(0.059)HQADIK;S(0.446)AS(0.446)AS(0.107)HQADIK 115.12 0.0013908 173976000.0 432208.0 410230.0 237041.0 111415.0 163716.2 192321.0 182577.0 166959.0 283542.0 54096.3 True False 426044.6346627606 409280.1376394568 217552.40398472105 119608.83076954474 154086.73499443344 184095.8791521478 192029.94370387806 174716.52465379596 251606.51413037203 63446.77337621119 6.71499293016061 6.450763622172042 3.428896260724433 1.8851838226716038 2.428598442363137 2.9015798496251493 3.02663056740846 2.7537495660780817 3.9656313590362924 1.0 15.953259176358081 -5.303673981018593 3.437351624527656 2.66497136261994 6.703895256668237 0.8229582308820486 0.7335046377051183 0.08695694787518612 2.102896973895234 0.19080662304197907 0.4905843024177365 4.9696524653293415e-06 5.303673981018593 4.038923894048297 S(ph)ASASPLTPCSVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SASASPLTPCSVTR 14 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.956)AS(0.044)ASPLTPCSVTR;S(0.999)AS(0.001)ASPLTPCSVTR;S(0.741)AS(0.257)AS(0.002)PLTPCSVTR 211.83 1.3985e-11 33538000.0 47451.0 54303.0 43424.0 65463.0 66926.0 58220.0 55875.0 59615.0 47720.0 43776.0 True False 55483.51710003009 59693.84296397547 44459.392846437084 61795.32034390956 53812.33073231093 55166.84070954756 50582.11550003142 58050.169417313715 48417.814722629584 51712.242269374656 1.0729280855974193 1.154346443788374 0.8597459884807026 1.194984352486807 1.0406110501261323 1.0668042670085263 0.9781458563823962 1.122561445216862 0.9362930826015232 1.0 15.658218241724695 -8.274241713114883 24.907578879396844 0.9681465357248346 1.058834015336509 0.14659668749635812 0.08971670987625423 1588.1668406577824 3089823.181248345 0.07904482664275458 0.02101237586432144 5.318121888243031e-09 8.274241713114883 0.09068747961167445 S(ph)ASDSGCDPASK ddPTM_PC-9_AZD4547_30min_R2 2 SASDSGCDPASK 12 0 Q7LBC6;H0Y9V5 Q7LBC6 KDM3B Lysine-specific demethylase 3B 1 S(0.959)AS(0.01)DS(0.031)GCDPASK;S(0.98)AS(0.019)DSGCDPASK 137.62 6.697e-05 65118000.0 89331.0 103940.0 117279.0 135229.0 109476.0 117805.0 96719.0 120673.0 98511.0 95087.0 True False 117736.39979977121 137536.57234251805 115723.80383126266 104054.04331722313 94277.14709331313 110438.63472703479 105326.80363047021 102025.76063967556 103718.09034580765 91758.0330722301 1.283118173501948 1.4989049758101505 1.261184443003123 1.1340047277965717 1.0274538799137078 1.2035854630852831 1.147875560361664 1.1119000399601298 1.1303434355895885 1.0 16.485546845583293 -5.588898539977845 3.255685189441285 1.1145629602785665 1.3915208586103278 0.7047985817059996 0.0739803389823567 0.12108495776431615 2.582219956921513 0.01971982010911592 0.03866909401142267 2.5769231083244765e-06 5.588898539977845 0.2769578983317613 S(ph)ASDSGCDPASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASDSGCDPASK 12 0 Q7LBC6;H0Y9V5 Q7LBC6 KDM3B Lysine-specific demethylase 3B 1 S(0.999)AS(0.001)DSGCDPASK 137.95 6.7939e-05 14328000.0 21065.0 28146.0 20262.0 28139.0 38743.0 39265.0 64083.0 44478.0 47854.0 46796.0 True False 24630.8884472853 30940.14886956621 20745.12292406291 26562.463057868867 31151.587268952564 37205.87427791797 58012.59431925747 43310.49962833646 48553.774219126455 55279.74436306783 0.4455680598939436 0.5597013739129588 0.37527530496184136 0.48050987507125914 0.5635262541077308 0.6730471478586478 1.0494367328879228 0.7834786525762595 0.8783284868365823 1.0 15.754463323658634 -6.922235582264397 2.2947031497667 0.91004958218331 0.4740806996311994 0.855118155738315 0.0855041803395716 0.10918615018948284 1.1676475500335493 0.034430592297611355 0.02864582033863406 1.196091537586647e-07 6.922235582264397 -0.4359688825521106 S(ph)ASDSGCDPASK ddPTM_PC-9_Lapatinib_30min_R1 2 SASDSGCDPASK 12 0 Q7LBC6;H0Y9V5 Q7LBC6 KDM3B Lysine-specific demethylase 3B 1 S(0.998)AS(0.001)DS(0.001)GCDPASK;S(0.977)AS(0.019)DS(0.004)GCDPASK 161.87 0.00053266 50182000.0 44174.0 76438.0 79915.0 77322.0 129794.0 174832.0 190948.0 202990.0 195695.0 147181.0 True False 43544.07065948052 76261.01250733671 73344.69718082073 83008.51781863053 122159.77210482226 167354.84291329776 200834.35312426044 212421.6564514283 173653.7683402923 172621.03974364538 0.2522523947494847 0.4417828360933857 0.42488851468941946 0.48087138127486734 0.7076760300264573 0.969492729054533 1.1634407568307656 1.2305664290221499 1.0059826345512726 1.0 17.39724879112004 -6.563776699348329 1.4317651934359144 1.1243120048785074 0.3763699029244264 0.9388045769437322 0.08195688248403514 0.08809415658423674 0.37276916330461474 0.03453508432969442 0.03700839797753787 2.730381298699384e-07 6.563776699348329 -0.747942101954081 down S(ph)ASDSGCDPASKK ddPTM_PC-9_AZD4547_30min_R2 1 SASDSGCDPASKK 13 1 Q7LBC6;H0Y9V5 Q7LBC6 KDM3B Lysine-specific demethylase 3B 1 S(0.9)AS(0.099)DSGCDPASKK 151.3 0.00019512 6832400.0 34252.0 35176.0 47091.0 59462.0 47793.0 51069.0 36785.0 50300.0 41509.0 41451.0 True False 45143.4235141414 46545.9540958285 46466.54257128721 45753.95457874211 41157.76691723046 47875.647356860434 40058.793738012566 42527.29077901178 43703.080997696976 39999.81310670247 1.1285908610052244 1.1636542893753956 1.1616689919858938 1.1438542089356776 1.0289489805224603 1.1968967762211435 1.0014745226722124 1.0631872370395101 1.092582129849351 1.0 15.287705638782864 -7.096624536045599 0.29042775575749574 0.9986079972182208 1.1868386943380902 0.42061777877273576 0.05168889208270709 2.106139687398771 0.45154430237209686 0.08000146218771377 0.14169767163201713 8.00526040872114e-08 7.096624536045599 0.1882306971198694 S(ph)ASDSGCDPASKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SASDSGCDPASKK 13 1 Q7LBC6;H0Y9V5 Q7LBC6 KDM3B Lysine-specific demethylase 3B 1 S(0.966)AS(0.032)DS(0.002)GCDPASKK;S(0.985)AS(0.015)DSGCDPASKK 57.788000000000004 0.031169 29097000.0 61423.0 75207.0 58653.0 86281.0 111753.0 116186.0 155305.0 137836.0 149973.0 123547.0 True False 71820.70074045111 82673.05393425224 60051.50996274119 81446.95529677637 89855.80187562278 110093.00162623645 140593.38608917015 134217.95104931368 152166.0714039591 145945.09310248593 0.49210767702903857 0.5664668278788747 0.4114664541724035 0.558065732566853 0.6156822402554091 0.7543453451287099 0.9633306821109929 0.9196468904580629 1.042625470779649 1.0 17.155066180475934 -6.937915566489296 1.2215139625498228 1.0012430463492892 0.49688759702135726 0.9550129723119501 0.046903185881464374 0.08488853490841647 0.2620659633621922 0.0250977370855504 0.019185139379516065 1.1536775286320945e-07 6.937915566489296 -0.5043554493279319 down S(ph)ASDSGCDPASKK ddPTM_PC-9_Lapatinib_30min_R1 2 SASDSGCDPASKK 13 1 Q7LBC6;H0Y9V5 Q7LBC6 KDM3B Lysine-specific demethylase 3B 1 S(0.998)AS(0.002)DS(0.001)GCDPASKK;S(0.922)AS(0.078)DSGCDPASKK 89.26 0.0091006 25102500.0 63660.0 71516.0 83162.0 74037.0 133758.0 167794.0 168678.0 180659.0 191873.0 163164.0 True False 62752.19672618578 71350.40909593 76324.74137460336 79481.92796019198 125890.61741834586 160617.84176691825 177411.32149220727 189053.0766681043 170262.24222773674 191366.67999763627 0.32791600255050085 0.37284656397242877 0.3988402859659064 0.415338385769005 0.657850245507216 0.8393197905136995 0.9270752959417942 0.987910103631622 0.8897172811371331 1.0 17.545980129825743 -6.547412453486016 1.3425243886890013 0.9572553931869898 0.3549090833932965 0.9852906574817402 0.03198455215762896 0.04365581977600547 0.1631613975440792 0.013352754001740921 0.014591519591229125 2.8352251099160303e-07 6.547412453486016 -0.6023463097936933 down S(ph)ASEPSLNR ddPTM_PC-9_AZD4547_30min_R2 1 SASEPSLNR 9 0 H7C560;P15056;A0A2R8Y8E0;A0A2U3TZI2 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 S(0.852)AS(0.144)EPS(0.004)LNR 133.75 0.0011541 67738000.0 23305.0 27622.0 55183.0 76657.0 53042.0 45022.0 35506.0 68665.0 46532.0 36700.0 True False 30715.505225886533 36550.27132234975 54451.23736406835 58984.91298884386 45678.03387156564 42206.767222788185 38665.96521576387 58054.40201472853 48991.58652303923 35415.14417061059 0.8672986075650633 1.0320520268467845 1.5375127968349467 1.6655279646663912 1.28978816665306 1.1917717183208207 1.0917918342924886 1.6392535841462201 1.3833513224462632 1.0 15.112078794879702 -5.0847666488802155 4.775678885013049 1.3657969302003559 0.9004772737655362 0.3751995508175733 0.21019829606867865 0.2065223819817132 8.00676442557832 0.05581671716264969 0.16666428735513278 8.226845685243893e-06 5.0847666488802155 -0.46531965643481965 S(ph)ASEPSLNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASEPSLNR 9 0 H7C560;P15056;A0A2R8Y8E0;A0A2U3TZI2 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 S(0.984)AS(0.016)EPSLNR 97.59700000000001 0.004732500000000001 58159000.0 15931.0 18621.0 58838.0 35479.0 41977.0 29202.0 30309.0 21915.0 27094.0 24241.0 True False 18627.803648407415 20469.569818098225 60240.921064357615 33491.22665446997 33751.90818441583 27670.595712817038 27437.912101842543 21339.754470861863 27490.198493187883 28635.70140834957 0.6505097738928071 0.7148269052746069 2.1036998607197597 1.1695619456593658 1.178665320716554 0.9662971169530659 0.9581714696131809 0.7452150085850399 0.9599973858217532 1.0 14.80552732109363 -6.845312840624061 2.7027257638576283 0.8982943870302396 1.1949257589867146 0.08941827332370533 0.37346413428027114 0.6792811708768404 10.083738026041429 0.15304228572384618 0.1351023114483607 1.4278650365866792e-07 6.845312840624061 0.29663137195647504 S(ph)ASEPSLNR ddPTM_PC-9_Lapatinib_30min_R1 1 SASEPSLNR 9 0 H7C560;P15056;A0A2R8Y8E0;A0A2U3TZI2 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 S(0.697)AS(0.302)EPS(0.001)LNR 112.11 0.0021902 61824000.0 27725.0 15264.0 45947.0 13614.0 24561.0 30199.0 24032.0 23090.0 34709.0 19013.0 True False 27329.63641585769 15228.657145817358 42169.41502054904 14615.218974972679 23116.3702687839 28907.45916730734 25276.259370520915 24162.845694189225 30799.70691802658 22299.37171676998 1.225578763517573 0.6829186642224914 1.891058436809501 0.6554094510197108 1.0366377386049628 1.2963351404904304 1.133496481047141 1.0835662098954044 1.3811916904754775 1.0 14.444715442436317 -6.734003426063202 24.981258695428973 1.1813021227084186 1.094677564492975 0.01427154785506457 0.3339348359727461 1385.8923303429385 1261893.3366283812 0.10669103104656681 0.10666730297435463 1.8450008642754508e-07 6.734003426063202 -0.08662455821544368 S(ph)ASHTEGTHDYGR ddPTM_PC-9_AZD4547_30min_R2 1 SASHTEGTHDYGR 13 0 O60303;A0A087X098;H3BNJ6 O60303 KIAA0556 Uncharacterized protein KIAA0556 1 S(0.853)AS(0.147)HTEGTHDYGR 77.068 0.0093697 1713500.0 6022.8 5556.0 7787.8 10164.0 7220.6 8475.6 7833.4 11201.0 7223.7 6510.4 True False 7937.925117977658 7351.868346498268 7684.528683541876 7820.846832234617 6218.144326628465 7945.61939215192 8530.557424693425 9470.142823373979 7605.530034524163 6282.472877611531 1.263503284871402 1.170218875547824 1.2231694164453566 1.2448675839262748 0.9897606321211017 1.2647280055067558 1.3578343418072296 1.5073909601937407 1.2105949651812316 1.0 12.617116822448113 -6.989238051491076 24.969344751993873 1.311243895978496 1.1783651942287428 0.062020643765622996 0.14034380445736605 382.806161108865 888164.2179991121 0.04796947700115895 0.04226381839255979 1.0250898857992614e-07 6.989238051491076 -0.13287870174975325 S(ph)ASHTEGTHDYGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SASHTEGTHDYGR 13 0 O60303;A0A087X098;H3BNJ6 O60303 KIAA0556 Uncharacterized protein KIAA0556 1 S(0.905)AS(0.095)HTEGTHDYGR;S(0.898)AS(0.102)HT(0.001)EGTHDYGR 106.14 0.0006525000000000001 3960100.0 10969.1 13433.099999999999 16434.1 13976.099999999999 18423.0 15499.599999999999 17626.4 15966.2 13800.3 11115.1 True False 12825.951980399577 14766.64939173487 16825.951270671314 13193.06442812756 14813.145400612068 14686.77369051362 15956.699787915046 15547.104167587251 14002.10327989742 13130.17964291682 0.9768298933608756 1.124634223850917 1.2814715204409413 1.004789331671076 1.1281753794285012 1.118550856875482 1.2152689621823274 1.1840739875919564 1.0664060706474008 1.0 13.680599034407232 -4.76654220613607 6.106670515251768 1.134845353892798 0.9717868511186066 0.21131972456021098 0.08396557797303772 0.17957130182171485 26.93094293145348 0.020239971956886902 0.12210268380656145 1.711818808555453e-05 4.76654220613607 -0.16305850277419143 S(ph)ASITNLSLDR ddPTM_PC-9_AZD4547_30min_R2 1 SASITNLSLDR 11 0 E9PDH4;Q9Y2I7-2;Q9Y2I7-3;Q9Y2I7-4;Q9Y2I7 E9PDH4 PIKFYVE 1-phosphatidylinositol 3-phosphate 5-kinase 1 S(0.895)AS(0.035)IT(0.07)NLSLDR 121.56 0.00075594 10178000.0 21016.0 17431.0 27952.0 43259.0 33932.0 27643.0 24538.0 42020.0 26610.0 31036.0 True False 27698.650840044265 23065.229868216593 27581.338216487657 33286.30589488758 29221.127508954505 25914.478840112264 26721.83446359529 35526.77452354025 28016.550274608322 29949.43908662317 0.924847065079619 0.770138959915233 0.9209300426867354 1.1114166712309084 0.9756819626717496 0.8652742632394371 0.8922315501905517 1.1862250381646773 0.9354616022549095 1.0 14.870241363046818 -5.522736754496712 24.999998189418367 0.9942551141308713 0.8470033683728929 0.2751792694542067 0.09665742123782356 6.117104249894424 1077003.324070514 0.026831615558005683 0.047115352749600166 3.0009809979430244e-06 5.522736754496712 -0.1472517457579784 S(ph)ASITNLSLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SASITNLSLDR 11 0 E9PDH4;Q9Y2I7-2;Q9Y2I7-3;Q9Y2I7-4;Q9Y2I7 E9PDH4 PIKFYVE 1-phosphatidylinositol 3-phosphate 5-kinase 1 S(0.724)AS(0.234)IT(0.01)NLS(0.032)LDR;S(0.965)AS(0.034)IT(0.001)NLSLDR 132.06 0.00012744 14601500.0 45212.0 42284.0 46041.0 40008.0 47721.0 45069.0 41036.0 44079.0 42703.0 31989.0 True False 52865.49862229589 46481.676074779294 47138.79205146485 37766.481467686084 38370.412618064816 42705.502300559936 37148.77300508794 42921.97295556101 43327.450588861044 37788.352475215324 1.3989892429676416 1.2300529933202502 1.2474423721537558 0.9994212235756088 1.0154031627399278 1.1301234243691805 0.9830746929084333 1.1358519264292544 1.1465821543100803 1.0 15.205653999823687 -5.333227572131573 1.5798820694658124 1.063717388322843 1.365910157274399 0.6899985294181504 0.07154561626490911 0.2766415000175563 1.1913604958020065 0.02133912757485053 0.09218390243646296 4.642719310308749e-06 5.333227572131573 0.302192768951556 S(ph)ASLPAYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASLPAYR 8 0 O94929;A0A0C4DGA7;O94929-2;O94929-3;A0A0A0MRD5;O94929-4 O94929 ABLIM3 Actin-binding LIM protein 3 1 S(0.624)AS(0.376)LPAYR 113.66 0.0037104 14972000.0 26927.0 35422.0 53782.0 61211.0 68766.0 40397.0 46150.0 47598.0 44755.0 35592.0 True False 31485.209267507777 38938.4620641574 55064.3668493708 57781.54611873957 55291.79594086144 38278.510205145845 41778.337902934225 46348.602934249706 45409.457206858475 42044.54785388302 0.7488535583003055 0.9261239340586996 1.3096672377292633 1.374293435608992 1.3150764787153009 0.910427443248403 0.9936683835470427 1.1023689229653395 1.0800320023578203 1.0 15.359631110014584 -6.778720795043212 24.9992637500424 1.0222205218575635 1.1462294324585884 0.09097673823211827 0.18361948343141635 704.7872797504513 1019537.6658363251 0.07285275707144057 0.06439797371485435 1.6644823908318724e-07 6.778720795043212 0.12400891060102492 S(ph)ASLSNLHSLDR ddPTM_PC-9_AZD4547_30min_R2 1 SASLSNLHSLDR 12 0 B0QY53;B0QY54;A0A087WUW0;Q9Y3M2 B0QY53 CBY1 Protein chibby homolog 1 1 S(0.808)AS(0.131)LS(0.062)NLHSLDR 74.296 0.011895999999999999 5262900.0 21117.0 20761.0 34438.0 51905.0 47099.0 43590.0 32045.0 43813.0 32601.0 39991.0 True False 27831.766739113762 27471.5872465174 33981.32961861054 39939.10417425602 40560.11683791843 40864.310409163 34896.94292060929 37042.707572581385 34324.222303739385 38590.92726231304 0.7211997408078242 0.7118664721317925 0.8805522963371726 1.0349350743188692 1.0510272676844554 1.05890978289786 0.904278424910738 0.9598812519013088 0.8894376149717342 1.0 15.235974088903317 -5.42676043697197 3.08589746448882 0.985706972459675 0.7147626060707641 0.7921160917029728 0.05456638252125011 0.11836138668703337 2.1344239379261065 0.01654314206263785 0.03893478672129868 3.7431700993363535e-06 5.42676043697197 -0.27094436638891084 S(ph)ASLSNLHSLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SASLSNLHSLDR 12 0 B0QY53;B0QY54;A0A087WUW0;Q9Y3M2 B0QY53 CBY1 Protein chibby homolog 1 1 S(0.5)AS(0.5)LSNLHSLDR;S(0.989)AS(0.01)LS(0.001)NLHSLDR 115.26 0.00041428 7978700.0 28144.0 40157.0 56553.0 51275.0 67109.0 64391.0 58346.0 59503.0 50458.0 40163.0 True False 32908.2233306621 44143.52157163256 57901.43799844685 48402.22798579294 53959.473195987426 61014.222606122894 52819.04449154061 57941.10929863987 51195.85279284245 47444.233969866924 0.6936190254765832 0.9304296408214593 1.2204104303848928 1.0201920009191099 1.1373241526095352 1.286019764696267 1.1132869070051246 1.2212465973302422 1.079074283828848 1.0 15.53394514269571 -4.9411658422509745 2.665222238542331 1.1432328697398697 0.6712867686291323 0.7170044326547298 0.08695365007432469 0.16756729199380077 2.0189358071041865 0.02205267485317284 0.15178655677870492 1.1450755926306638e-05 4.9411658422509745 -0.4719461011107374 S(ph)ASPCIADK ddPTM_PC-9_Lapatinib_30min_R1 1 SASPCIADK 9 0 Q05209-2;Q05209-3;Q05209 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 S(0.647)AS(0.353)PCIADK 98.75399999999999 0.0043606 13489000.0 111200.0 112580.0 137530.0 127570.0 124820.0 127670.0 111180.0 120250.0 121630.0 97306.0 True False 109614.26760841736 112319.3279268944 126222.81428115265 136951.92336104446 117478.33300556202 122209.85171330592 116936.35639208196 125837.2539942078 107930.74857931864 114125.21244790507 0.960473722302626 0.9841762877608223 1.106002885547922 1.2000146192372623 1.029381067388484 1.070840080749828 1.0246321026167649 1.1026244884463978 0.9457222139111984 1.0 16.800258020273944 -9.75017997466468 10.671923270876107 1.0 1.0526257039891591 0.03126151763371121 0.07303004804000038 0.0 0.0 0.07306035125638216 0.01771973795734069 1.7775426313126616e-10 9.75017997466468 0.05262570398915911 S(ph)ASPDDDLGSSNWEAADLGNEER ddPTM_PC-9_AZD4547_30min_R2 3 SASPDDDLGSSNWEAADLGNEER 23 0 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 S(0.836)AS(0.164)PDDDLGSSNWEAADLGNEER;S(0.537)AS(0.463)PDDDLGSSNWEAADLGNEER;S(0.82)AS(0.18)PDDDLGSSNWEAADLGNEER 135.63 9.321700000000002e-07 11109300.0 17476.5 17307.5 20925.4 30776.7 22847.300000000003 22890.5 14700.18 24862.1 17834.8 18327.0 True False 23033.6634662178 22901.81090839072 20647.915523586533 23681.607310275005 19675.34676810494 21459.15341640161 16008.467541977923 21020.23371922204 18777.511117534163 17685.377308304658 1.302412895392495 1.294957439083674 1.1675134300861498 1.3390501597698259 1.112520610960663 1.2133839749251416 0.9051810013949041 1.1885657485719239 1.0617534921755196 1.0 14.110269378063167 -6.663633801157979 1.4444440025538516 1.0591081938619107 1.2704480476447435 0.532239425365536 0.09091233912780611 0.32746899338338586 1.4217638641041 0.03810007998434785 0.037487889207945685 2.1695326924080633e-07 6.663633801157979 0.21133985378283282 S(ph)ASPDDDLGSSNWEAADLGNEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASPDDDLGSSNWEAADLGNEER 23 0 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 S(0.5)AS(0.5)PDDDLGSSNWEAADLGNEER 89.87899999999999 1.2209000000000001e-05 5331200.0 21448.0 23942.0 26885.0 25056.0 29283.0 28022.0 25416.0 25924.0 23883.0 16972.0 True False 25078.722782690475 26318.803532834292 27526.0403619303 23652.193552648027 23545.206359774384 26552.4769900883 23008.412484094824 25243.52246874848 24232.24369280305 20048.889249721913 1.250878413777378 1.3127312543361647 1.3729459033403608 1.1797258819700494 1.1743895667487398 1.3243864365431912 1.147615321602615 1.2590983048648752 1.2086576663163104 1.0 14.291234690129533 -14.522878745266912 0.15424077108153073 0.08889881803080499 1.3217234558745852 0.5958414707572375 0.06444108473745275 95.28747695744097 0.8578600811632257 26.5121660016805 0.3081748964636675 3.0000000000927427e-15 14.522878745266912 1.2328246378437802 S(ph)ASPDDDLGSSNWEAADLGNEER ddPTM_PC-9_Lapatinib_30min_R1 1 SASPDDDLGSSNWEAADLGNEER 23 0 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 S(0.5)AS(0.5)PDDDLGSSNWEAADLGNEER 71.67 0.005194300000000001 0.0 2809.5 2907.7 6346.6 2184.4 3927.3 5294.1 3659.7 3213.9 4593.8 3032.8 True False 2769.436014800802 2900.9673992985554 5824.80704658447 2345.048062944785 3696.3039353688773 5067.683684149863 3849.181358950371 3363.2295269187844 4076.397869141449 3557.0154390480193 0.7785841985386487 0.8155622175412752 1.6375546146472142 0.659274074889144 1.0391588112865027 1.4247010649765837 1.0821379397724924 0.9455200812451073 1.1460163552825158 1.0 11.796451521021275 -5.041244533486793 24.99990421231358 1.1135666060613043 0.7878267753302199 0.20752129260854646 0.25030970606822495 647.788069775882 392649.4120255238 0.06221208240606851 0.16463848594931688 9.094010818383823e-06 5.041244533486793 -0.32573983073108437 S(ph)ASPDDDLGSSNWEAADLGNEERK ddPTM_PC-9_Lapatinib_30min_R1 1 SASPDDDLGSSNWEAADLGNEERK 24 1 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 S(0.539)AS(0.46)PDDDLGSSNWEAADLGNEERK 82.773 0.00058489 0.0 3481.0 2743.6 3863.7 2396.9 3099.0 2622.2 3303.3 2797.9 3413.6 2069.0 True False 3431.3603016627835 2737.247362766281 3546.0415003133025 2573.1760218240047 2916.722912868421 2510.054618646752 3474.328710828968 2927.900648236123 3029.1244211984076 2426.623893230792 1.4140470269145384 1.1280064333010118 1.4613065956389826 1.0603934252036455 1.201967441680925 1.0343813994614883 1.431754101045823 1.20657373250287 1.2482875610218485 1.0 11.244734804598002 -11.231938963561392 2.476841332944799 0.9547576471154945 1.2377804828529348 0.20435730352237147 0.14349707817278096 19924296.38863432 15120916.414812554 5599300.509416369 0.03384395412113754 5.862205470947333e-12 11.231938963561392 0.28302283573744036 S(ph)ASPDGGPR ddPTM_PC-9_AZD4547_30min_R2 1 SASPDGGPR 9 0 O75420 O75420 GIGYF1 PERQ amino acid-rich with GYF domain-containing protein 1 1 S(0.508)AS(0.492)PDGGPR 72.243 0.03281 22152000.0 48804.0 37075.0 48419.0 65213.0 43978.0 54908.0 50359.0 49199.0 59689.0 66718.0 True False 64322.65681373809 49058.76870885953 47776.932423587394 50179.15038080638 37872.41381553703 51474.594079979885 54840.85344169024 41596.42503054872 62844.038682491366 64382.22312737867 0.9990748018513942 0.7619924619843887 0.742082675975042 0.7793944965449259 0.58824333761522 0.7995156361428938 0.8518011770607694 0.6460855653935902 0.9761085534147518 1.0 15.974374773691379 -8.355533087174443 7.283492109938292 0.9949145545779532 0.7677917253436636 0.4073661549323244 0.10470795394451028 0.2818842562126054 18.757201963342233 0.09952185877083518 0.025773184065369176 4.410287616089601e-09 8.355533087174443 -0.2271228292342896 S(ph)ASPDGGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASPDGGPR 9 0 O75420 O75420 GIGYF1 PERQ amino acid-rich with GYF domain-containing protein 1 1 S(0.568)AS(0.432)PDGGPR 96.665 0.0050318 12858000.0 36134.0 40844.0 40320.0 43948.0 64745.0 55775.0 39919.0 43493.0 58028.0 53721.0 True False 42250.772520968734 44898.722391407726 41281.381714451534 41485.73604133839 52058.6820258714 52850.060813724085 36137.58333146762 42351.35483464268 58876.54972180949 63460.19204479797 0.665783874261568 0.7075100302204052 0.650508301098586 0.6537284982064453 0.8203360303278315 0.8328065061072624 0.5694527887018888 0.6673688413162366 0.9277713764283476 1.0 15.953564266730913 -8.360470700786435 4.122230429607813 0.9925671687074022 0.6979611825502371 0.6721462214331159 0.0753975869179638 0.14097280930235684 3.9485856502710774 0.07711293845400523 0.020430993663595853 4.360429801822573e-09 8.360470700786435 -0.29460598615716516 S(ph)ASPDGGPR ddPTM_PC-9_Lapatinib_30min_R1 1 SASPDGGPR 9 0 O75420 O75420 GIGYF1 PERQ amino acid-rich with GYF domain-containing protein 1 1 S(0.624)AS(0.376)PDGGPR 100.02 0.0039549 20680000.0 67134.0 86928.0 90132.0 76345.0 98730.0 75814.0 99734.0 99313.0 92891.0 73889.0 True False 66176.65684913233 86726.7235568403 82721.69487958148 81959.66597945431 92922.89551064842 72571.61195106586 104897.73851779007 103927.44453993152 82428.63739440504 86660.61519909615 0.763630129985767 1.0007628420083594 0.9545477457035667 0.9457544905625033 1.0722621261938328 0.8374232260449354 1.2104430400914594 1.199246558556804 0.9511660770585524 1.0 16.403088857810914 -3.2644606891638133 0.4241930310754983 1.069480110112709 8.68858341427295e-12 0.31434981025966224 0.11062427550166523 23.204377520342895 1.1807400490809883 0.07864898157667834 16.443207258608968 0.0005439253637370975 3.2644606891638133 -1.0694801101040203 S(ph)ASPEPAPRSPVPPPK ddPTM_PC-9_AZD4547_30min_R2 1 SASPEPAPRSPVPPPK 16 1 J3QS60;O94989 J3QS60 ARHGEF15 Rho guanine nucleotide exchange factor 15 1 S(0.557)AS(0.443)PEPAPRSPVPPPK 67.252 0.011937999999999999 6567800.0 21580.0 32891.0 24313.0 22775.0 25863.0 29395.0 39953.0 46289.0 36820.0 30841.0 True False 28441.991108115497 43522.37253143894 23990.59373416801 17524.57562024236 22272.368877876077 27556.926003150893 43508.739600783345 39136.09866540113 38766.230030480205 29761.26597726979 0.955671412964694 1.4623831044243618 0.8061012509511813 0.5888383791746891 0.7483676566341845 0.9259325871485955 1.4619250281225673 1.3150011392422412 1.302573286367857 1.0 14.861148276300588 -7.24147193126873 22.057924540635895 1.2961248754298265 0.912162251867454 0.3477868578325076 0.23728024459910915 209.1487087731472 231045.15332048762 0.09896763185138234 0.07648697576827869 5.734929305646159e-08 7.24147193126873 -0.38396262356237243 S(ph)ASPHDVDLCLVSPCEFEHR ddPTM_PC-9_AZD4547_30min_R2 2 SASPHDVDLCLVSPCEFEHR 20 0 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 S(0.5)AS(0.5)PHDVDLCLVSPCEFEHR;S(0.5)AS(0.5)PHDVDLCLVSPCEFEHR 66.264 0.0034376999999999997 10614300.0 8197.2 9032.2 16458.1 22346.2 17635.3 18576.5 15560.0 20650.1 16805.2 14814.0 True False 10803.739087648022 11951.682015702245 16239.854840468483 17194.628835348405 15186.943002436215 17414.908518371565 16944.809856285865 17459.101537090875 17693.488563504237 14295.366369030671 0.7557511160436662 0.8360528654651511 1.1360222901072567 1.2028113440029538 1.0623682255067661 1.2182205106753359 1.1853358227316875 1.22131193327889 1.237707947229336 1.0 13.803259974125703 -5.229190011809515 3.1834295801224997 1.1705767151175162 0.7688213673198054 0.804005575925442 0.07197477391703233 0.09560911681791057 1.9588359784312626 0.01848693854013028 0.0562502980582999 5.899429128437199e-06 5.229190011809515 -0.4017553477977107 S(ph)ASPHDVDLCLVSPCEFEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SASPHDVDLCLVSPCEFEHR 20 0 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 S(0.5)AS(0.5)PHDVDLCLVSPCEFEHR;S(0.854)AS(0.146)PHDVDLCLVSPCEFEHR;S(0.5)AS(0.5)PHDVDLCLVSPCEFEHR;S(0.5)AS(0.5)PHDVDLCLVSPCEFEHR;S(0.5)AS(0.5)PHDVDLCLVSPCEFEHR 133.94 3.2511e-05 27699800.0 66520.8 94272.9 129690.20000000001 116943.4 140677.5 94921.0 112475.0 90120.9 83862.5 68686.9 True False 77781.45759431158 103631.6904841086 132782.50622082248 110391.44043361816 113112.75373688372 89943.1756611295 101820.55375151712 87755.32186598648 85088.83041023722 81139.29124479863 0.9586164286257269 1.2772072431770451 1.6364760424171736 1.3605176818782567 1.3940564676072977 1.1085033438333767 1.2548859151890144 1.0815391719558798 1.0486760372791866 1.0 16.308113080145397 -7.543920962640628 1.0171039031567548 1.0151403891117408 1.3322084010422384 0.3185233783227984 0.16613735478797362 0.6812713550829393 1.2991970233065349 0.14421156465006263 0.06640533890034789 2.8581106443046307e-08 7.543920962640628 0.3170680119304976 S(ph)ASPHDVDLCLVSPCEFEHR ddPTM_PC-9_Lapatinib_30min_R1 2 SASPHDVDLCLVSPCEFEHR 20 0 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 S(0.5)AS(0.5)PHDVDLCLVSPCEFEHR;S(0.872)AS(0.128)PHDVDLCLVSPCEFEHR 111.6 3.001e-05 20765800.0 17262.7 23383.9 34300.0 25500.5 33808.0 31130.1 26063.2 33734.0 34979.0 20560.8 True False 17016.53073240853 23329.756016252548 31479.986401828886 27375.89183717427 31819.479909085378 29798.73819080744 27412.624967782966 35301.40479202164 31039.296674800546 24114.70688445612 0.7056494948888249 0.9674492884377733 1.3054268730141723 1.1352363505119045 1.3195051493491552 1.235708081942938 1.1367596172380854 1.4638952470442943 1.2871521442712572 1.0 14.557625653720931 -4.97054005290757 2.403350984841065 1.248956757947596 0.673654429558111 0.6585830103010899 0.12129434111292418 0.21227274607728538 2.019940000051304 0.03117343158546229 0.21663804603260997 1.0701876800573183e-05 4.97054005290757 -0.575302328389485 S(ph)ASPPPATSSSSSSR ddPTM_PC-9_Lapatinib_30min_R1 1 SASPPPATSSSSSSR 15 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 S(0.906)AS(0.094)PPPATSSSSSSR 94.023 0.016202 0.0 1344.3 2658.2 2497.9 970.42 2859.9 2089.0 934.4 1114.6 3389.4 916.12 True False 1325.130035485572 2652.0451012193216 2292.532304172841 1041.787924026222 2691.6863047797337 1999.6583396968442 982.778659945686 1166.3883850473494 3007.650080035703 1074.4701213468315 1.2332870027363276 2.46823531760476 2.1336398831632355 0.9695829631077663 2.5051290410995763 1.8610646308063956 0.9146635540816977 1.0855475288464045 2.7991937795959 1.0 10.069409649806483 -7.044720871068671 24.76692870775188 1.4471062668883596 1.893364056592837 0.08218129011273356 0.6703583878092334 1044.368965264584 578380.113787568 0.25201750835076914 0.1952231097560345 9.021507799625984e-08 7.044720871068671 0.44625778970447727 S(ph)ASPSSQGWQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASPSSQGWQGR 12 0 X6R7H2;Q5VV67-2;Q5VV67 X6R7H2 PPRC1 Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 1 S(0.6)AS(0.006)PS(0.394)SQGWQGR 130.19 0.0010834000000000002 0.0 6853.9 5710.1 8411.1 6120.5 8110.6 8210.0 7924.0 9794.5 6810.4 7164.5 True False 8014.129899304469 6276.96099126377 8611.652523274386 5777.588227928726 6521.386152429263 7779.453147121011 7173.381355208031 9537.404753130575 6909.989215989026 8463.367135849203 0.9469197980740017 0.7416623774568121 1.0175208501586885 0.682658348053456 0.7705427459014416 0.9191912653970471 0.8475800754079261 1.126904292350967 0.8164586393422111 1.0 13.047016035919812 -7.578816708856771 24.99991490681981 0.9804579922231462 0.8422763549417887 0.2166739439256835 0.11706740565159203 126.99512299730468 56755.27704919621 0.05239035906477288 0.030247590657500215 2.6374442670551436e-08 7.578816708856771 -0.13818163728135757 S(ph)ASRSPK ddPTM_PC-9_Lapatinib_30min_R1 1 SASRSPK 7 1 O95104-2;O95104-3;O95104 O95104-2 SCAF4 Splicing factor, arginine/serine-rich 15 1 S(1)ASRSPK 58.167 0.039739 12528000.0 11822.0 8307.9 9204.6 11006.0 8258.9 6852.2 7168.9 8984.1 8319.3 6031.6 True False 11653.416112110717 8288.663567985855 8447.833318783505 11815.41795493971 7773.127739622136 6559.147379258365 7540.070564302899 9401.534084069533 7382.292827887245 7074.15402339819 1.647322927033585 1.1716826549960042 1.1941828366815013 1.6702234522827049 1.0988066861298253 0.9271988364352247 1.0658618033143838 1.3289976515882174 1.0435583963071582 1.0 12.788341915402034 -6.426482467506992 13.504689360189234 1.0843271250971132 1.3867933138581876 0.4611778245257241 0.1803460871076864 1.2513096153251722 172.34508143627082 0.05672806353338817 0.06432020662586575 3.745566676049267e-07 6.426482467506992 0.30246618876107445 S(ph)ASSGAEGDVSSEREP ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASSGAEGDVSSEREP 16 1 Q8TEA8 Q8TEA8 DTD1 D-tyrosyl-tRNA(Tyr) deacylase 1 1 S(0.588)AS(0.109)S(0.303)GAEGDVSSEREP 164.7 0.00028126 4862600.0 6813.9 8681.6 10937.0 9688.0 10390.0 11743.0 12112.0 11796.0 8808.3 5874.8 True False 7967.358689340484 9543.451873304417 11197.779558803473 9145.212768919784 8354.154085239066 11127.176407629973 10964.663676713748 11486.367498895115 8937.104723833567 6939.8547351087855 1.148058423908147 1.3751659418782949 1.6135466787444137 1.3177815844839047 1.2037937974371895 1.603373101073354 1.57995579089623 1.6551308258349389 1.28779420678947 1.0 12.760689749319868 -6.766309895422574 24.999196140857855 1.47586549405108 1.3489740885749693 0.01643173344342308 0.2131079434125186 352.53574961689594 1809469.9338418166 0.07292168506117595 0.06633872331807893 1.712734731380229e-07 6.766309895422574 -0.12689140547611077 S(ph)ASSSWLEGTSTQAK ddPTM_PC-9_AZD4547_30min_R2 1 SASSSWLEGTSTQAK 15 0 Q9BZL4-3;K7EL81;Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-3;Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 S(0.487)AS(0.487)S(0.025)S(0.001)WLEGTSTQAK 112.12 0.00035141 11899000.0 25798.0 32600.0 45104.0 48076.0 51561.0 51957.0 37506.0 47519.0 42793.0 49137.0 True False 34001.22736826521 43137.31247225408 44505.89148956992 36992.82096679571 44402.64515764481 48708.12057648277 40843.96134125048 40176.03042798929 45054.95061635904 47416.72858613877 0.7170724000180121 0.9097488114113448 0.9386116000963473 0.7801639225193141 0.9364341759044283 1.027234944899204 0.8613829456212275 0.8472965475676839 0.950191039318766 1.0 15.533108510202318 -4.7614817056017875 9.615829117602395 0.9108217090948993 0.7160889093665633 0.42551019266711254 0.06930666094737065 0.07761139713098573 129.35962128927736 0.01734408656804245 0.09840925939642171 1.7318819837178986e-05 4.7614817056017875 -0.19473279972833601 S(ph)ASTDLGTADVVLGR ddPTM_PC-9_Lapatinib_30min_R1 1 SASTDLGTADVVLGR 15 0 Q9Y2K5-2;H7C0E9;A0A0U1RRA6;B5MCU0;B5MCG9;Q9Y2K5;Q9Y2K5-3 Q9Y2K5-2 R3HDM2 R3H domain-containing protein 2 1 S(0.71)AS(0.145)T(0.145)DLGTADVVLGR 193.98 1.436e-09 15607000.0 26832.0 19823.0 21554.0 20012.0 22468.0 23356.0 19856.0 23815.0 22781.0 42673.0 True False 26449.37075961384 19777.101061421497 19781.913320846073 21483.74923807501 21146.47641378758 22357.118325495212 20884.04652384584 24921.53184093185 20215.16388543499 50048.97119180168 0.5284698192546745 0.39515499700543505 0.39525114802132977 0.42925456261115275 0.4225157063218814 0.44670485312907776 0.41727224409493496 0.4979429396345743 0.40390768089847084 1.0 15.61105279283168 -13.606939062683516 0.5762937929823271 9.999999999999998 0.43339284622944646 0.9412425899600421 0.04214561067644324 403.4505669516302 4.216723087602226 4637.278838958751 0.01678464019432434 2.4720709852599575e-14 13.606939062683516 -9.566607153770551 S(ph)ASWGSADQLK ddPTM_PC-9_AZD4547_30min_R2 1 SASWGSADQLK 11 0 Q86VQ1;H7C0Q2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 S(0.982)AS(0.018)WGSADQLK 171.62 0.0026022 33484000.0 114820.0 120640.0 150130.0 156680.0 159650.0 164330.0 137760.0 143070.0 169310.0 127640.0 True False 151330.3715956361 159634.52075621864 148139.17810680045 120559.84668186936 137485.35325959505 154054.41912222444 150020.3731235183 120961.81892153516 178259.3809467846 123171.36245059225 1.2286165272900937 1.2960360069107206 1.2027079603525823 0.9787977033235266 1.116212003538928 1.250732443460795 1.2179809505939012 0.9820612236067178 1.447246968777258 1.0 16.91030734042844 -5.523767349604521 24.99995434983116 1.1433687023923718 1.2590877222781394 0.11245196807164892 0.13642778979569045 61.15653673681917 1720563.7396466525 0.03570484686672849 0.06250428899878484 2.9938680142163933e-06 5.523767349604521 0.1157190198857676 S(ph)ASWGSADQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASWGSADQLK 11 0 Q86VQ1;H7C0Q2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 S(0.942)AS(0.019)WGS(0.039)ADQLK 138.2 9.900200000000001e-05 26190000.0 119460.0 147840.0 112520.0 116740.0 128670.0 89882.0 121920.0 80509.0 92553.0 90114.0 True False 139682.2185574505 162516.5781594784 115202.9035344761 110199.4362761866 103458.03716532356 85168.42969178215 110370.85497563904 78395.72405633652 93906.41253192635 106450.95485796836 1.3121744069259011 1.5266803231245347 1.0822157836741342 1.0352132249374337 0.971884538784663 0.8000720125565589 1.0368235317654104 0.7364492329912457 0.8821566011993082 1.0 16.699829365163396 -5.557365233225823 1.5462306909096115 0.8959315875191668 1.4372717958389252 0.7602664029349644 0.10877941259850143 0.18706078788852123 0.8571772830212034 0.03254459822855527 0.0969748833234812 2.770988776736401e-06 5.557365233225823 0.5413402083197584 S(ph)ASWGSADQLK ddPTM_PC-9_Lapatinib_30min_R1 1 SASWGSADQLK 11 0 Q86VQ1;H7C0Q2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 S(0.945)AS(0.055)WGSADQLK 161.25 0.0012935 31134000.0 132440.0 192520.0 180680.0 171500.0 197980.0 207530.0 206290.0 207470.0 189200.0 175140.0 True False 130551.38131347887 192074.2317683933 165825.18784496957 184112.68210722844 186335.2056436558 198654.42567605845 216970.68681527782 217109.81360647207 167890.3036356745 205412.71564061972 0.6355564742247278 0.9350649552992485 0.8072781050959348 0.8963061587158178 0.9071259540215562 0.9670989697814752 1.0562670676866928 1.0569443713811615 0.8173316004906306 1.0 17.648165965848783 -3.676093712300791 0.4891695769013615 0.9840149826396923 7.764146064379761e-12 0.533051815976472 0.0835754618127125 10.437957757382414 0.8366809355968756 0.04975711678785019 7.462297794389758 0.00021081731980846768 3.676093712300791 -0.9840149826319282 S(ph)ASYPCAAPRPGAPETTALHGGFQR ddPTM_PC-9_AZD4547_30min_R2 1 SASYPCAAPRPGAPETTALHGGFQR 25 1 Q7Z3C6;H7C152;Q7Z3C6-2 Q7Z3C6 ATG9A Autophagy-related protein 9A 1 S(0.515)AS(0.117)Y(0.365)PCAAPRPGAPET(0.002)T(0.001)ALHGGFQR 47.155 0.016381 4077800.0 6880.1 5040.6 8643.1 13205.0 8626.8 5558.4 9839.4 9826.3 7435.6 8257.3 True False 9067.828685029906 6669.875375694595 8528.486846698788 10160.79126521627 7429.1177294073095 5210.832369311577 10715.087538556503 8307.871120910602 7828.630635921741 7968.21444032651 1.1380000818173686 0.8370602254300383 1.0703134197213346 1.27516538884713 0.9323441010584662 0.6539523262501523 1.3447288120571006 1.0426264482623755 0.9824824237035656 1.0 12.960040758352303 -8.2620441300042 22.609900549426182 0.9912412277529196 1.0332045538753727 0.008835807919472027 0.18991352429038852 133.74311973840616 4997717.945743798 0.1532410821807075 0.048764806196637964 5.469603817357321e-09 8.2620441300042 0.041963326122453126 S(ph)ATASPQQPQAQQR ddPTM_PC-9_AZD4547_30min_R2 2 SATASPQQPQAQQR 14 0 Q9BX66-4;Q9BX66-9;Q9BX66-8;Q9BX66-10;Q9BX66-6;Q9BX66-5;Q9BX66-12;A0A0U1RQI5 Q9BX66-4 SORBS1 Sorbin and SH3 domain-containing protein 1 1 S(0.972)AT(0.026)AS(0.002)PQQPQAQQR;S(0.986)AT(0.004)AS(0.01)PQQPQAQQR 204.35 1.103e-10 4067900.0 6072.700000000001 6165.3 8793.900000000001 14109.7 10101.2 9655.2 7327.7 11051.7 9152.6 9783.5 True False 8003.692279993185 8158.112655987359 8677.28714016781 10856.926657691934 8698.822739403853 9051.45881767724 7979.85110436413 9343.913707801285 9636.387750596767 9440.982642865634 0.8477605120947256 0.8641169001780006 0.9191084729644181 1.149978457581034 0.92138954899757 0.9587411777011633 0.8452352266947919 0.9897183440817251 1.0206975391358013 1.0 13.204721311644334 -5.524456222006996 24.999971185471157 0.9785173837948301 0.8648571699423043 0.32896419524850273 0.07312776120271612 62.03354642714712 983106.2162853737 0.020730380685440537 0.0362425388271543 2.989122943000567e-06 5.524456222006996 -0.11366021385252578 S(ph)ATASPQQPQAQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SATASPQQPQAQQR 14 0 Q9BX66-4;Q9BX66-9;Q9BX66-8;Q9BX66-10;Q9BX66-6;Q9BX66-5;Q9BX66-12;A0A0U1RQI5 Q9BX66-4 SORBS1 Sorbin and SH3 domain-containing protein 1 1 S(0.9)AT(0.099)AS(0.001)PQQPQAQQR 200.76 3.837e-08 1596900.0 2920.9 2913.8 4480.8 3157.3 4565.5 4188.6 4492.0 3167.7 2869.9 2286.5 True False 3415.3506795953276 3203.0628073666617 4587.639265528632 2980.4067171047095 3670.923048715976 3968.9424423911196 4066.4852407363064 3084.5512314555813 2911.8668581826178 2701.0243500759602 1.264464972150021 1.1858696524807644 1.698481268930291 1.103435708390001 1.3590855071753574 1.469421200249269 1.5055344616282136 1.1419931224865985 1.0780602026415378 1.0 11.399290930645762 -7.923494433398716 5.6096582443286405 1.060606889423038 1.3676579635668498 0.42491205672250776 0.1602650985495114 0.19728114011501732 10.547317566349106 0.09083248172875302 0.04234109464307272 1.1926295523743642e-08 7.923494433398716 0.3070510741438117 S(ph)ATFPNAGPR ddPTM_PC-9_AZD4547_30min_R2 2 SATFPNAGPR 10 0 Q86X27;Q86X27-3 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 S(0.64)AT(0.36)FPNAGPR;S(0.905)AT(0.095)FPNAGPR 139.31 0.00012086 109101000.0 65194.0 73864.0 88005.0 109845.0 126788.0 84752.0 87112.0 100316.0 73687.0 100111.0 True False 85924.33588055974 97739.09351075388 86837.99619855455 84521.93233833254 109185.67472018521 79452.44404215131 94864.79924169506 84814.46723235288 77581.9443850079 96606.14436141665 0.8894293054394675 1.0117275061211295 0.8988868852242138 0.8749125937800039 1.1302145991015524 0.8224367566612427 0.9819747995199252 0.8779407127050893 0.8030746377245256 1.0 16.559827330078825 -7.782849681959986 24.348955926175332 0.8803806814205046 0.9448817545546702 0.05347629620729222 0.09249996644335581 459.36639097063596 522406.3560871822 0.04794603570066638 0.02307098709151569 1.6487329523568415e-08 7.782849681959986 0.06450107313416553 S(ph)ATFPNAGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SATFPNAGPR 10 0 Q86X27;Q86X27-3 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 S(0.624)AT(0.376)FPNAGPR;S(0.624)AT(0.376)FPNAGPR;S(0.591)AT(0.409)FPNAGPR 124.39 0.00041448 148027000.0 88239.0 85926.0 83132.0 112665.0 112384.0 91140.0 92838.0 83085.0 88411.0 75597.0 True False 103176.11990030874 94456.16541484924 85114.18215986546 106352.74531485808 90363.1619552944 86360.45795719975 84043.71255108557 80904.10678583429 89703.84361782085 89302.13767447716 1.155360023702958 1.0577144945752528 0.9531035244657013 1.190931685224978 1.0118812864781006 0.9670592463530898 0.9411164697696317 0.9059593520677495 1.0044982791431936 1.0 16.446407089895445 -6.516337268199466 6.4105661724012215 0.9594343767717437 1.0803714438403258 0.45476455276493244 0.06443957519291518 0.14232229034807828 27.351302971816885 0.020878296705946566 0.022144335220005095 3.0455289475733007e-07 6.516337268199466 0.1209370670685821 S(ph)ATFPNAGPR ddPTM_PC-9_Lapatinib_30min_R1 1 SATFPNAGPR 10 0 Q86X27;Q86X27-3 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 S(0.621)AT(0.379)FPNAGPR 123.01 0.00049114 78277000.0 63348.0 79151.0 70338.0 53787.0 47440.0 68326.0 59569.0 56428.0 69138.0 48303.0 True False 62444.64590339954 78967.73072252297 64555.08115253178 57742.67540817207 44649.67247062853 65403.856255685336 62653.19134664447 59049.85088054177 61350.950384583884 56652.10919029821 1.1022475031537453 1.3939062790630639 1.1395000481921504 1.0192502315176049 0.7881378665116828 1.154482281250808 1.1059286625355504 1.0423239615349429 1.0829420344881062 1.0 15.78984204895337 -5.544546732261643 4.641667913051967 1.029603212708101 1.2536593038434265 0.38287940590374026 0.11258949981205878 0.18488140352526736 9.982810617768038 0.031196161092931655 0.05890151945151522 2.8539953930629975e-06 5.544546732261643 0.22405609113532554 S(ph)ATPEPVTDNR ddPTM_PC-9_Lapatinib_30min_R1 1 SATPEPVTDNR 11 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 S(0.519)AT(0.48)PEPVT(0.001)DNR 102.05 0.003481 6812200.0 22887.0 33700.0 31801.0 27541.0 35224.0 33983.0 41868.0 47463.0 33659.0 34632.0 True False 22560.62718303824 33621.96972052185 29186.444535409926 29566.45701408274 33152.1935730485 32529.62630824215 44035.72017830264 49668.30425220021 29867.968975016767 40618.09505576067 0.5554329210187461 0.8277584085212634 0.7185576895061836 0.7279134330030446 0.816192722173136 0.8008653843461974 1.084140458036012 1.222812251141157 0.7353365275750601 1.0 15.309834959950347 -7.122528293034186 3.6615970463086813 1.0282460968368332 0.7384806310748427 0.49855203307747387 0.132941874542719 0.20080047654370264 4.832615331233664 0.05214759512648966 0.039753280268910805 7.541742619669181e-08 7.122528293034186 -0.28976546576199047 S(ph)ATPVNCEQPDILVSSTPINEGQTVLDK ddPTM_PC-9_AZD4547_30min_R2 1 SATPVNCEQPDILVSSTPINEGQTVLDK 28 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 S(0.5)AT(0.5)PVNCEQPDILVSSTPINEGQTVLDK 106.89 1.5091e-10 15921000.0 46522.0 45071.0 64936.0 61307.0 60067.0 74217.0 57242.0 77418.0 59670.0 68435.0 True False 61315.02828228678 59639.31933855718 64074.90621157136 47173.61833370798 51727.73388189235 69576.19925755577 62336.427107552416 65454.826988658795 62824.0343812806 66039.11147999277 0.9284653731427444 0.903090880570456 0.9702569397982211 0.7143284831746973 0.7832893678099198 1.0535604991995478 0.9439319474556812 0.9911524477201515 0.9513155609356402 1.0 16.011033089261076 -6.763724473511066 24.99999283970316 0.984685356619342 0.860331637126185 0.4332313925197443 0.07321279479003524 67.18719772092349 735051.5054575931 0.02717322226012133 0.025121312503083103 1.7229613149265982e-07 6.763724473511066 -0.12435371949315699 S(ph)ATPVNCEQPDILVSSTPINEGQTVLDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SATPVNCEQPDILVSSTPINEGQTVLDK 28 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 S(0.5)AT(0.5)PVNCEQPDILVSSTPINEGQTVLDK;S(0.831)AT(0.169)PVNCEQPDILVSSTPINEGQTVLDK 180.38 1.1693e-18 21585000.0 96931.0 102044.0 98802.0 122722.0 126716.0 94289.0 117657.0 102120.0 91019.0 79932.0 True False 113339.50382548339 112174.25393469795 101157.81438867137 115846.28421009245 101886.90943841691 89344.31885370186 106511.67719708651 99439.45820508397 92349.98068396929 94423.0388586362 1.2003373879458343 1.187996650930052 1.071325553714894 1.2268857856135058 1.0790471337292493 0.9462131269410016 1.128026363952855 1.0531270694852135 0.9780449962241679 1.0 16.52685129413439 -5.8827247055943745 0.4144612804793722 1.0002537292827711 1.250126452091665 0.517335477704381 0.06405728112748524 2.047412884941879 0.5268897616577053 0.060501632021079346 0.2333048523161624 1.310012061830515e-06 5.8827247055943745 0.24987272280889394 S(ph)ATPVNCEQPDILVSSTPINEGQTVLDK ddPTM_PC-9_Lapatinib_30min_R1 2 SATPVNCEQPDILVSSTPINEGQTVLDK 28 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 S(0.827)AT(0.173)PVNCEQPDILVSSTPINEGQTVLDK;S(0.752)AT(0.248)PVNCEQPDILVSSTPINEGQTVLDK 126.52 2.7394999999999996e-11 30639000.0 27237.5 40564.0 52364.0 46060.0 51852.0 52993.0 44247.0 40052.0 50102.0 42683.0 True False 26849.08825525423 40470.076550244754 48058.834050885365 49447.40605165576 48802.167304954266 50726.612922716566 46537.89315776627 41912.96213701462 44458.98516255058 50060.69967847751 0.5363306631288935 0.8084201141847797 0.9600112335534774 0.9877490000986657 0.9748598724826788 1.0133021162012514 0.9296292991640748 0.8372428353220595 0.8881015536757417 1.0 15.611390834691067 -4.808866799609971 2.25362525639728 0.9468939664544395 0.4463254223402967 0.8583406209399952 0.051182887195169335 0.22540624087805183 1.4278054871377723 0.015380364169473495 0.22353210184660993 1.5528632081993545e-05 4.808866799609971 -0.5005685441141428 S(ph)ATYCEQLLQHVQAVPATQ ddPTM_PC-9_AZD4547_30min_R2 2 SATYCEQLLQHVQAVPATQ 19 0 E9PGY2;H0Y650;Q86Y56-3;Q86Y56 E9PGY2 DNAAF5 Dynein assembly factor 5, axonemal 1 S(0.96)AT(0.04)YCEQLLQHVQAVPATQ;S(0.785)AT(0.214)Y(0.001)CEQLLQHVQAVPATQ 146.67 0.00016437 5536900.0 11022.8 9904.2 12419.599999999999 18638.4 15053.8 12983.3 11527.3 14165.099999999999 14461.3 13658.400000000001 True False 14527.821111516925 13105.538962812843 12254.907989177513 14341.604840409458 12963.839717502631 12171.45219856127 12553.207368660926 11976.209276615895 15225.694794670924 13180.223573293399 1.1022439058586315 0.994333585461184 0.9297951526413544 1.0881154451332165 0.9835826870016668 0.9234632577268139 0.9524274985818167 0.9086499337448908 1.155192452540956 1.0 13.68608722222819 -4.76532863809032 5.687985957434872 0.9869194646448081 1.1070060596261657 0.16453677741399986 0.07304071174512602 0.24243491246201834 26.78601314859907 0.01775970173515996 0.11394488345243052 1.7166089081194418e-05 4.76532863809032 0.12008659498135765 S(ph)ATYCEQLLQHVQAVPATQ ddPTM_PC-9_Lapatinib_30min_R1 2 SATYCEQLLQHVQAVPATQ 19 0 E9PGY2;H0Y650;Q86Y56-3;Q86Y56 E9PGY2 DNAAF5 Dynein assembly factor 5, axonemal 1 S(0.933)AT(0.065)Y(0.002)CEQLLQHVQAVPATQ;S(0.831)AT(0.169)YCEQLLQHVQAVPATQ 122.49 3.2155e-05 5001400.0 17142.7 15393.2 19249.4 13119.9 15741.4 18556.4 14231.2 17555.8 19317.1 14378.900000000001 True False 16898.241954413836 15357.557991155396 17666.78863683281 14084.78121270338 14815.521800783137 17762.786029081162 14968.021902203607 18371.506558598834 17141.404779919074 16864.273706320088 1.0020142135193773 0.9106563531046088 1.0475866879586977 0.83518457171535 0.8785152600571731 1.0532790405568635 0.8875580509935724 1.0893743115491474 1.0164330275009192 1.0 14.041682566695696 -7.7642819820839 24.99939574363947 1.0396777473198984 0.9449847870719146 0.2505578181243149 0.0714437672602971 102.17219809850803 898523.5323924517 0.03630713825539685 0.018661226496155665 1.720750949694884e-08 7.7642819820839 -0.09469296024798379 S(ph)AVDLSCSR ddPTM_PC-9_AZD4547_30min_R2 4 SAVDLSCSR 9 0 Q9Y446;Q9Y446-2;E9PK71;E9PQ15 Q9Y446 PKP3 Plakophilin-3 1 S(1)AVDLSCSR;S(1)AVDLSCSR;S(1)AVDLSCSR;S(0.988)AVDLS(0.012)CSR 163.9 0.00015022 367086000.0 98859.0 116192.0 138417.0 181950.0 127378.0 134997.0 130659.0 163711.0 106735.0 140099.0 True False 130294.10560505975 153748.7917415994 136581.50013993884 140004.23859947745 109693.76340432676 126555.61624927202 142287.39787997783 138413.2266545287 112376.79419617883 135194.17665281697 0.9637553098138187 1.1372441886785647 1.010261710389232 1.0355789137206175 0.8113793516863075 0.9361025702628519 1.0524669139069243 1.0238105670037723 0.831225108791232 1.0 17.044673484821416 -6.0429918076439515 24.99836107367377 0.9465587053931752 1.0430725345962883 0.23689640412847657 0.08243850461042679 703.4926952014721 409057.2231503584 0.024816667605752723 0.03204092289494678 9.057496864340419e-07 6.0429918076439515 0.09651382920311313 S(ph)AVDLSCSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SAVDLSCSR 9 0 Q9Y446;Q9Y446-2;E9PK71;E9PQ15 Q9Y446 PKP3 Plakophilin-3 1 S(1)AVDLSCSR;S(0.995)AVDLS(0.005)CSR;S(1)AVDLSCSR;S(1)AVDLSCSR 147.28 0.00039065 310870000.0 100645.0 101666.0 132617.0 116658.0 168930.0 154886.0 148276.0 119121.0 125758.0 119534.0 True False 117682.21067063988 111758.72859281312 135779.09223277302 110122.0304703391 135829.3791741516 146763.50549878005 134230.223854723 115994.19996913253 127596.97283923805 141204.56796937686 0.8334164564432626 0.7914668073418866 0.961577193892336 0.7798758358456318 0.961933322182672 1.0393679723633924 0.9506082259593303 0.8214620931688859 0.903632047278457 1.0 17.10742723500178 -5.255366301277966 24.93768466424815 0.9217363405336386 0.8124416226773966 0.2736093070742326 0.07442181209690438 677.3967962413207 2781551.6065635877 0.02000801729688609 0.05012763235809075 5.554355831372688e-06 5.255366301277966 -0.10929471785624201 S(ph)AVDLSCSR ddPTM_PC-9_Lapatinib_30min_R1 4 SAVDLSCSR 9 0 Q9Y446;Q9Y446-2;E9PK71;E9PQ15 Q9Y446 PKP3 Plakophilin-3 1 S(1)AVDLSCSR;S(1)AVDLSCSR;S(1)AVDLSCSR;S(1)AVDLSCSR 169.21 0.00085678 363412000.0 128011.0 142830.0 131383.0 137246.0 155341.0 138076.0 124110.0 115597.0 158045.0 82624.0 True False 126185.53966565737 142499.28591044882 120581.1968930463 147339.52867923424 146204.14779215667 132170.8113508767 130535.80852510626 120968.05862759631 140244.3078123688 96905.44831044025 1.302151136656602 1.4704981855503831 1.2443180336647317 1.5204462829295884 1.5087299046776625 1.3639151735562125 1.3470430280341916 1.2483101903627811 1.4472283061225915 1.0 16.564290160045182 -11.920482580192513 0.35478741201092573 0.44513342332058276 1.4017535634652034 0.5860993331151713 0.09639481769674496 39.10204640567475 1.7026119210509678 16.972353982924478 0.07384307538259147 1.2009292420279186e-12 11.920482580192513 0.9566201401446206 S(ph)AVEAQNEVTENPK ddPTM_PC-9_AZD4547_30min_R2 4 SAVEAQNEVTENPK 14 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 S(1)AVEAQNEVTENPK;S(1)AVEAQNEVTENPK;S(1)AVEAQNEVTENPK;S(0.999)AVEAQNEVT(0.001)ENPK 268.08 1.4458999999999998e-56 25187300.0 93659.0 91464.0 136584.0 157778.0 143159.0 138634.0 131266.0 153507.0 124359.0 141436.0 True False 123440.613771779 121027.94932399526 134772.80691759964 121404.7197458003 123283.8439542149 129965.19406432475 142948.4197040633 129786.02038993534 130932.3628560697 136484.36868976802 0.9044304117518559 0.8867531900234997 0.9874596498588143 0.8895137290172468 0.9032817833845999 0.9522350091220959 1.0473611086481869 0.9509222311379981 0.9593213062638832 1.0 17.058376205764503 -6.994126249333498 7.214366953637912 0.9873987381980399 0.9164585060402567 0.49344947611185497 0.03584008736105296 0.12202655214806261 38.875947651785616 0.013170111432925666 0.011188551361668662 1.0136166847026969e-07 6.994126249333498 -0.07094023215778322 S(ph)AVEAQNEVTENPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SAVEAQNEVTENPK 14 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 S(1)AVEAQNEVTENPK;S(1)AVEAQNEVTENPK 241.66 1.0609999999999999e-27 11338100.0 41752.0 42064.0 53219.0 53454.0 73363.0 63016.0 69106.0 63054.0 62768.0 51046.0 True False 48819.78896041092 46239.835928708635 54487.94279418145 50459.14568020626 58988.04679070206 59711.33002667206 62559.779395886675 61398.89931123537 63685.863254610515 60300.23572008635 0.8096119090982057 0.7668267856091628 0.9036107760360083 0.8367984814261353 0.9782390746285724 0.9902337746049952 1.0374715562686874 1.0182198888284453 1.0561461741250937 1.0 15.879876021335422 -6.178410234603234 0.9129072662531421 1.0345274384363674 0.7900763704753438 0.8786819970355085 0.034066271493909284 0.18164904606516144 0.3187163129263082 0.015432636330472751 0.027616572730084776 6.63116394668727e-07 6.178410234603234 -0.24445106796102356 S(ph)AVEAQNEVTENPK ddPTM_PC-9_Lapatinib_30min_R1 3 SAVEAQNEVTENPK 14 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 S(0.998)AVEAQNEVT(0.002)ENPK;S(1)AVEAQNEVTENPK;S(0.997)AVEAQNEVT(0.003)ENPK 145.46 0.00018547 18087100.0 61944.0 74949.0 93147.0 76724.0 97703.0 99480.0 94449.0 81461.0 102530.0 80034.0 True False 61060.667200861615 74775.46019535275 85488.8132178179 82366.53890376103 91956.30163148874 95225.47229920633 99339.10707749371 85245.97544800134 90981.9917112353 93867.77026139839 0.6504966191358637 0.7966042017097209 0.9107365923335861 0.8774741178403483 0.9796365821347766 1.0144639851785877 1.0582877040847887 0.9081495726447161 0.9692569820064234 1.0 16.51834226942333 -4.079555156058665 0.6471510385378973 0.9896946478864921 1.8250661738724072e-08 0.8623988854302622 0.04232710177964417 2.7158841847212196 0.44365106511215646 0.01995238081668345 2.4412135610051457 8.326161757515401e-05 4.079555156058665 -0.9896946296358303 S(ph)AVFPGEGK ddPTM_PC-9_AZD4547_30min_R2 2 SAVFPGEGK 9 0 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 S(1)AVFPGEGK;S(1)AVFPGEGK 119.27 0.0017472999999999998 45148000.0 209073.0 225300.0 241080.0 304950.0 292600.0 331680.0 218280.0 256100.0 196938.0 252390.0 True False 275553.86501144647 298123.8190183696 237883.12168112607 234648.48893053393 251977.5406436431 310939.9971670379 237706.49713560892 216525.6295925426 207347.7406231043 243553.90292153702 1.131387597185082 1.2240568327677868 0.9767165248744224 0.9634355521131925 1.0345863384698861 1.2766783592345465 0.9759913279328072 0.8890254970058853 0.8513423030215334 1.0 17.893881576812177 -7.51218679215991 22.991851859358306 0.9086118965566126 1.0946687011469876 0.429151639381229 0.09898335517101947 183.10480358209415 393753.4932827174 0.046596811431680506 0.029180947252275383 3.074774055086527e-08 7.51218679215991 0.186056804590375 S(ph)AVFPGEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SAVFPGEGK 9 0 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 S(1)AVFPGEGK;S(1)AVFPGEGK;S(1)AVFPGEGK 107.11 0.0025241 30893300.0 192074.0 198068.0 200565.0 222256.0 238774.0 194939.0 220031.0 148675.0 175087.0 173047.0 True False 224588.3345655772 217730.88205419027 205347.23024699808 209803.7168836744 191987.94875350126 184716.05566950326 199188.07079351108 144772.43878418338 177647.31614293868 204419.0512607016 1.0986663580546274 1.065120304156542 1.0045405698763015 1.0263413101164705 0.939188141073277 0.9036146803848015 0.9744105041338866 0.7082140235527795 0.8690350290119478 1.0 17.641170131957594 -6.2771079373146215 0.7973166038350914 0.8604848476997646 1.0849070982746059 0.5012746952119167 0.07531692530743853 0.5344135498406177 0.7340001795176041 0.04164090672928487 0.07003281588663944 5.28313931032505e-07 6.2771079373146215 0.22442225057484122 S(ph)AVFPGEGK ddPTM_PC-9_Lapatinib_30min_R1 4 SAVFPGEGK 9 0 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 S(1)AVFPGEGK;S(1)AVFPGEGK;S(1)AVFPGEGK;S(1)AVFPGEGK 119.27 0.0017472999999999998 45916500.0 279523.0 284055.0 281344.0 229324.0 273596.0 299433.0 243486.0 237139.0 259121.0 181044.0 True False 275536.95076175913 283397.28809978697 258212.98233924643 246189.25196243753 257503.6211904316 286626.9486024153 256092.51369385226 248157.34365848132 229936.06431490282 212337.2141740342 1.2976385313971655 1.334656711976597 1.216051474272484 1.1594258355516418 1.212710744991589 1.3498667660181898 1.206065148259672 1.1686945438357712 1.0828816098455751 1.0 17.695997714259093 -8.22088871394196 1.3360727745324799 1.003681233031658 1.2566079643745267 0.709055408365671 0.055755168180902745 0.25033810095500236 0.8548516940448276 0.057260929353930436 0.018163504168613558 6.013278053581114e-09 8.22088871394196 0.2529267313428687 S(ph)AVLLVDETATTPIFANR ddPTM_PC-9_AZD4547_30min_R2 4 SAVLLVDETATTPIFANR 18 0 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36;A0A087WX73 Q12802-2 AKAP13 A-kinase anchor protein 13 1 S(1)AVLLVDETATTPIFANR;S(0.999)AVLLVDET(0.001)ATTPIFANR;S(1)AVLLVDETATTPIFANR;S(1)AVLLVDETATTPIFANR 166.77 1.2308e-07 40575200.0 9631.82 11850.2 19615.0 24579.799999999996 25955.9 23927.600000000002 18373.8 16447.4 18579.3 15336.0 True False 12694.538405698273 15680.545406708761 19354.89228378668 18913.306864124406 22352.371316446784 22431.403389453764 20009.03260523298 13905.832253652454 19561.3638676073 14799.091307915112 0.8577917482615135 1.0595613663335002 1.3078432912590352 1.2780046065401904 1.5103880941995333 1.5157284270187996 1.3520446755086506 0.9396409525641003 1.3217949305539554 1.0 13.853220973929917 -5.000260085699422 2.309423603791313 1.29677581703036 0.8364014944677969 0.36299577197677413 0.17744051802639726 0.42641848213642997 3.7569801912687866 0.05035274078598551 0.3315714597183765 9.994013098321308e-06 5.000260085699422 -0.46037432256256317 S(ph)AVLLVDETATTPIFANR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SAVLLVDETATTPIFANR 18 0 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36;A0A087WX73 Q12802-2 AKAP13 A-kinase anchor protein 13 1 S(1)AVLLVDETATTPIFANR;S(1)AVLLVDETATTPIFANR;S(1)AVLLVDETATTPIFANR;S(1)AVLLVDETATTPIFANR 202.35 1.4607e-15 28642400.0 14885.900000000001 16952.0 20642.4 23434.800000000003 21299.5 17007.4 19166.7 16464.0 16366.4 12837.0 True False 17405.788860073302 18634.882528134953 21134.593102737934 22121.8241326467 17126.015874740096 16115.502004183429 17351.09142110877 16031.837445049954 16605.727637813165 15164.246482363911 1.147817590561873 1.2288696672008996 1.3937120533695864 1.4588145977694627 1.1293680760635045 1.0627301543090737 1.1442105904364037 1.057212929352939 1.095057882178696 1.0 13.888386191183443 -6.444055511150394 7.223958663153541 1.0815746852390327 1.307469585721955 0.6283085223870146 0.08588428051798143 0.19679176960499767 15.725460161655919 0.028782521103096027 0.032551624788748276 3.5970335524106745e-07 6.444055511150394 0.22589490048292227 S(ph)AVLLVDETATTPIFANR ddPTM_PC-9_Lapatinib_30min_R1 4 SAVLLVDETATTPIFANR 18 0 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36;A0A087WX73 Q12802-2 AKAP13 A-kinase anchor protein 13 1 S(1)AVLLVDETATTPIFANR;S(1)AVLLVDETATTPIFANR;S(1)AVLLVDETATTPIFANR;S(1)AVLLVDETATTPIFANR 216.77 1.5183e-27 24698100.0 8128.76 15724.24 17234.5 13062.5 12956.6 15979.3 18700.94 11581.73 18447.800000000003 11322.2 True False 8012.842391767982 15687.831488374424 15817.545937093873 14023.159825222609 12194.518261655687 15295.902588567635 19669.183168797812 12119.85945698407 16370.014500053889 13279.22718411681 0.60341180105361 1.181381361344471 1.1911495840671458 1.0560222843386255 0.9183153577070708 1.1518669254234128 1.4811993872899458 0.9126931325853472 1.232753553582843 1.0 13.696883567643566 -6.884800679830896 8.045023598200277 1.1727610442224823 1.015948338275079 0.12838334720262368 0.20872464713823197 0.5617504790547123 37.31004598162086 0.07329447598368535 0.06466074097965384 1.3037650062639615e-07 6.884800679830896 -0.15681270594740337 S(ph)AVLLVDETATTPIFANRR ddPTM_PC-9_AZD4547_30min_R2 2 SAVLLVDETATTPIFANRR 19 1 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36;A0A087WX73 Q12802-2 AKAP13 A-kinase anchor protein 13 1 S(1)AVLLVDETATTPIFANRR;S(0.999)AVLLVDETATTPIFANRR 93.029 0.00038643 4102700.0 7097.700000000001 6135.9 10218.599999999999 16412.7 13072.1 7825.6 7532.9 8966.6 8337.3 11293.3 True False 9354.62095866873 8119.209680935694 10083.094687285371 12629.005588687249 11257.264555870694 7336.263994905855 8203.313506839064 7581.018001969924 8777.992657064704 10897.925004412997 0.8583855142039128 0.7450234496610968 0.9252306914575326 1.1588449712741893 1.032973208322886 0.6731798935976449 0.7527408661297651 0.6956386650578044 0.8054737625291192 1.0 13.41176584750406 -6.761032183411999 24.999999991633512 0.7643424434143475 0.9439151453796165 0.26124896838635114 0.13104970730124985 15.009975803516022 921571.5713099771 0.047927797780390684 0.045147924351428365 1.7336755188918912e-07 6.761032183411999 0.17957270196526898 S(ph)AVLLVDETATTPIFANRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAVLLVDETATTPIFANRR 19 1 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36;A0A087WX73 Q12802-2 AKAP13 A-kinase anchor protein 13 1 S(1)AVLLVDETATTPIFANRR 80.382 0.0011431 1981300.0 2209.3 1060.1 2046.7 3223.4 2881.0 3925.9 3928.3 2706.6 4085.4 2776.2 True False 2583.2908543359804 1165.339722043173 2095.5010901529745 3042.8033484038024 2316.488731431545 3720.018892848038 3556.182985570887 2635.5546178797504 4145.141246182542 3279.50308361289 0.7877080119985976 0.3553403342921597 0.6389690866960398 0.9278245120756754 0.7063535762495967 1.1343239503070845 1.0843664100639268 0.8036445006102179 1.263954062703919 1.0 11.679261516237887 -6.099932133940125 1.069902088681983 1.0411664176365774 0.5521158941114769 0.5350447050740879 0.17350610201102393 0.39872174814370115 0.9397512443486691 0.07043704430753181 0.12857843972845898 7.944523720136775e-07 6.099932133940125 -0.4890505235251005 S(ph)AVLLVDETATTPIFANRR ddPTM_PC-9_Lapatinib_30min_R1 1 SAVLLVDETATTPIFANRR 19 1 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36;A0A087WX73 Q12802-2 AKAP13 A-kinase anchor protein 13 1 S(1)AVLLVDETATTPIFANRR 63.614 0.005778 968120.0 6169.8 4306.2 3483.6 4352.5 5468.7 4955.1 2852.3 2597.2 4529.4 2322.2 True False 6081.817520597254 4296.229258472138 3197.1918550848727 4672.597369514366 5147.041817877873 4743.181923902267 2999.9781375889156 2717.87539354475 4019.2512753035116 2723.5891758630005 2.233015747931279 1.577414573587747 1.173889176612624 1.715602856305889 1.889801099039459 1.741518862660091 1.1014796813613925 0.997902113002619 1.4757186255999735 1.0 11.41129338939106 -7.261542969865165 24.999967598245142 1.1436002590270111 1.6977470414086289 0.5096096673969941 0.2772119913260306 8.732105839938482 2106993.0636622077 0.11550863129156427 0.08352338723899622 5.475919185672921e-08 7.261542969865165 0.5541467823816177 S(ph)AVPPGADK ddPTM_PC-9_Lapatinib_30min_R1 1 SAVPPGADK 9 0 P46783;F6U211;A0A2R8Y7H1;S4R435;A0A2R8YFH6;A0A1W2PQS6 P46783 RPS10;RPS10-NUDT3 40S ribosomal protein S10 1 S(1)AVPPGADK 78.342 0.044787 0.0 60334.0 52158.0 64724.0 56554.0 48291.0 57672.0 40857.0 48197.0 53675.0 34830.0 True False 59473.62609609948 52037.231355577984 59402.64256186512 60713.16981861355 45450.61832375894 55205.5029999983 42972.37554516363 50436.40857179897 47629.55627719257 40850.319091942285 1.455891347194657 1.2738512822496486 1.4541536977512197 1.486234897748674 1.1126135446203667 1.3514093458057608 1.051947120619675 1.2346637601111796 1.1659531023488992 1.0 15.318059727212079 -6.264274907549875 24.98625660830786 1.1693890383089294 1.4098856211518518 0.5986584916525027 0.10560466644050678 185.546229481673 1635004.8656245011 0.0310833691936698 0.036814050513313955 5.441580928022783e-07 6.264274907549875 0.2404965828429224 S(ph)AVTLPR ddPTM_PC-9_AZD4547_30min_R2 1 SAVTLPR 7 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.999)AVT(0.001)LPR 86.67 0.018456999999999998 5587700.0 8848.8 8978.7 14545.0 21273.0 15216.0 13125.0 12685.0 18751.0 15203.0 10388.0 True False 11662.534333526062 11880.889186951774 14352.123796465828 16368.838514573703 13103.52104727844 12304.291675160926 13813.940425898862 15853.463805114307 16006.599542460359 10024.319281861122 1.1634240695654288 1.1852065814034964 1.4317305138550218 1.6329127249760398 1.3071731534917383 1.2274441115842534 1.3780427416049097 1.5815002853910436 1.596776707963013 1.0 13.291216650940173 -5.254643113570587 15.273579558590505 1.4140651771870294 1.1743039708305776 0.1846049664634084 0.1813456615219378 4.0774658456592965 9139.004347136697 0.04662242373293928 0.11445359039962272 5.563612656659072e-06 5.254643113570587 -0.23976120635645182 S(ph)AVTLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SAVTLPR 7 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.998)AVT(0.002)LPR;S(0.982)AVT(0.018)LPR 96.948 0.012642 2078900.0 22015.7 34189.4 29708.0 26574.5 33077.7 28633.4 26644.1 29048.0 25802.0 20538.2 True False 25742.52318010438 37583.49768212701 30416.35138821741 25085.61692069146 26596.362135256237 27131.81409778012 24120.177961420803 28285.520778900078 26179.305437411742 24261.613079698265 1.0610392266804929 1.5490931109430761 1.2536821557701507 1.0339632751658507 1.096232226929365 1.118302151165851 0.9941704157175018 1.1658549118718309 1.0790422446938688 1.0 14.56638785353285 -5.636901639250517 4.9890419858538735 1.0772674759461074 1.32651723146229 0.4066170820662166 0.1206125043936578 0.1761073627840701 6.916894694177997 0.03090440703957576 0.0547090677733132 2.3072696892067315e-06 5.636901639250517 0.24924975551618256 S(ph)AVTLPR ddPTM_PC-9_Lapatinib_30min_R1 2 SAVTLPR 7 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.993)AVT(0.007)LPR;S(0.98)AVT(0.02)LPR 106.68 0.010019 11617100.0 20567.0 36652.0 37321.0 32445.0 35525.0 32540.0 34357.0 35131.0 31708.0 23781.0 True False 20273.710808474138 36567.134545892164 34252.61144322615 34831.11353334718 33435.48934483727 31148.34005444485 36135.8373499079 36763.31451202086 28136.71113995754 27891.514163809316 0.7268773824685476 1.3110487416039935 1.2280656848551696 1.248806835253941 1.1987692438806907 1.1167676258631176 1.2955853575277037 1.3180824209150739 1.0087910959121174 1.0 14.767538636515987 -4.753672139493616 24.99972421872428 1.2057446353059431 0.7268765224535407 0.6100307115771951 0.11100443980864282 177.80793236732552 572248.271009616 0.026094800092513616 0.2750316358922274 1.763306711413601e-05 4.753672139493616 -0.4788681128524024 S(ph)CDSPLNLK ddPTM_PC-9_AZD4547_30min_R2 1 SCDSPLNLK 9 0 Q8N1G0 Q8N1G0 ZNF687 Zinc finger protein 687 1 S(0.835)CDS(0.165)PLNLK 88.681 0.0099307 8682200.0 44365.0 34813.0 52946.0 67255.0 53972.0 54688.0 38256.0 46918.0 42919.0 47080.0 True False 58472.14715067395 46065.6214446804 52243.90144569819 51750.39882939193 46478.919424534164 51268.35071475816 41660.709888307974 39667.90116838318 45187.610719124925 45431.743530036714 1.2870328674930935 1.0139523131931885 1.1499426917471853 1.1390801850952013 1.023049432250055 1.1284698039568444 0.9169956213713092 0.873131825595845 0.994626382525901 1.0 15.471413052187572 -7.260265631477488 24.991077510881244 0.935616103340391 1.1159366637388124 0.5464334614512614 0.07875936665509632 79.04584207886538 1683044.105522877 0.029979404982221965 0.021880777347150694 5.49204855954271e-08 7.260265631477488 0.18032056039842137 S(ph)CGPASQSTLGLK ddPTM_PC-9_Lapatinib_30min_R1 1 SCGPASQSTLGLK 13 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6;Q9BXS6-7;H0YMD2 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 S(1)CGPASQSTLGLK 96.67299999999999 0.0032042000000000004 4005600.0 15260.0 11184.0 12188.0 11296.0 16230.0 12307.0 11151.0 12441.0 15257.0 9017.1 True False 15042.38960165873 11158.104135142907 11185.94968704054 12126.745522351353 15275.3833094077 11780.658299018216 11728.344217737964 13019.054278103431 13538.595996667469 10575.693720469497 1.4223548827386936 1.0550706582534761 1.0577036346457234 1.1466619441597254 1.4443859394151939 1.1139371667143199 1.108990533173014 1.2310354878096321 1.2801615056668298 1.0 13.368464680649321 -10.690846094135562 4.561773852122425 0.9999724858707016 1.198196782995137 0.17632135466818688 0.13288688445878363 4.3213243032581745e-05 7.88138097210026e-06 0.12963533287488307 0.031436156397780544 2.037764095352788e-11 10.690846094135562 0.19822429712443534 S(ph)CHDLDLLGQSPGWGQTQAVETNIVCK ddPTM_PC-9_Lapatinib_30min_R1 3 SCHDLDLLGQSPGWGQTQAVETNIVCK 27 0 Q9P0V3;Q9P0V3-2 Q9P0V3 SH3BP4 SH3 domain-binding protein 4 1 S(1)CHDLDLLGQSPGWGQTQAVETNIVCK;S(0.999)CHDLDLLGQS(0.001)PGWGQTQAVETNIVCK;S(0.996)CHDLDLLGQS(0.004)PGWGQTQAVETNIVCK 141.38 8.9799e-10 14499800.0 55053.4 61873.2 73652.1 57534.0 71942.7 62197.1 53449.1 53776.2 81331.1 52364.4 True False 54268.32842044294 61729.936406878085 67596.70864332769 61765.24228779767 67711.17183079029 59537.07502152162 56216.432869545184 56274.83857166991 72170.73506354867 61415.51676882289 0.8836256906331501 1.0051195472186405 1.100645442710703 1.0056944162871932 1.102509193005168 0.9694142157205644 0.9153457599510588 0.9162967525535403 1.1751221655466975 1.0 15.906315581354365 -4.770772795076655 5.101674069330459 1.0187584373535405 0.876470973674788 0.2155109402804638 0.07895822195172668 0.2646710523386508 18.69300439844672 0.020080723541293557 0.13258176456817275 1.6952244398631026e-05 4.770772795076655 -0.14228746367875256 S(ph)CPELTSGPR ddPTM_PC-9_AZD4547_30min_R2 4 SCPELTSGPR 10 0 Q13111;Q13111-3;Q13111-2 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 S(1)CPELTSGPR;S(1)CPELTSGPR;S(1)CPELTSGPR;S(1)CPELTSGPR 193.3 1.0694e-26 45645300.0 31401.699999999997 29673.5 45232.2 43826.9 41377.2 42845.0 34249.0 29187.600000000002 35251.9 45668.3 True False 41386.78740406442 39264.878578080694 44632.391473805554 33723.28532385511 35632.69000246119 40165.89537693484 37297.094650895546 24677.32708432376 37115.24346581979 44069.46671734867 0.9391261226170415 0.8909769394287549 1.0127735776806048 0.7652301658231636 0.8085573222612608 0.9114223150134666 0.8463250733236791 0.5599642773668765 0.8421986066649807 1.0 15.427491818282078 -5.7693898274078395 24.999912701068837 0.8053067542103228 0.9419606914645564 0.21472626501239478 0.11029097346202395 251.9478774302072 792243.1821576308 0.03130738300890616 0.047387306321751047 1.7006313180855065e-06 5.7693898274078395 0.13665393725423358 S(ph)CPELTSGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SCPELTSGPR 10 0 Q13111;Q13111-3;Q13111-2 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 S(1)CPELTSGPR;S(1)CPELTSGPR;S(1)CPELTSGPR;S(1)CPELTSGPR 185.99 0.00016013 50178500.0 42144.7 51013.5 51077.7 57504.7 68541.4 48349.3 66575.3 39388.7 57126.0 47084.0 True False 49278.96531423235 56077.783143523644 52295.586081255926 54282.89809175284 55111.20469855684 45813.7775939218 60268.80562056812 38354.78836077737 57961.35967822581 55619.95648326107 0.8859943162498328 1.008231337980287 0.9402306184290953 0.9759608155768582 0.9908530711479909 0.8236931578274345 1.0835823943642626 0.6895868099486974 1.0420964585916097 1.0 15.763314995478062 S(ph)CPELTSGPR ddPTM_PC-9_Lapatinib_30min_R1 4 SCPELTSGPR 10 0 Q13111;Q13111-3;Q13111-2 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 S(1)CPELTSGPR;S(1)CPELTSGPR;S(1)CPELTSGPR;S(1)CPELTSGPR 189.17 0.00016698 60293000.0 24713.9 36127.1 39560.6 23722.499999999996 34409.5 35165.5 26661.199999999997 20837.2 31813.799999999996 21228.5 True False 24361.475254025794 36043.44991959243 36308.08017633214 25467.131785940146 32385.600861679883 33661.55353978431 28041.586481746504 21805.372381938487 28230.594829834157 24897.817939801793 0.9784582453340781 1.447654971481383 1.4582836240556583 1.0228660137010739 1.3007405283459832 1.3519880987631756 1.1262668298702219 0.8757945147908041 1.1338581918339345 1.0 14.603731688695365 -7.510463038164851 6.13571034261062 1.0019031641927825 1.2669539809928638 0.34471806610547917 0.15933342210021642 0.1717149894647344 26.719013877081856 0.07112555463823575 0.044184538154548654 3.087002362393055e-08 7.510463038164851 0.26505081680008136 S(ph)CSLGSLGALGPACCR ddPTM_PC-9_Lapatinib_30min_R1 1 SCSLGSLGALGPACCR 16 0 Q15633-2;Q15633 Q15633-2 TARBP2 RISC-loading complex subunit TARBP2 1 S(0.924)CS(0.068)LGS(0.008)LGALGPACCR 153.14 3.1554e-05 2925300.0 6411.0 7670.1 6737.4 4405.8 4803.7 7393.3 5337.4 4899.8 7688.6 5886.1 True False 6319.577964366588 7652.34035469954 6183.476979116092 4729.817229317953 4521.155810437572 7077.105793624067 5613.744455901227 5127.462595599322 6822.628903452682 6903.504542264755 0.9154159203744646 1.1084718359856576 0.895701153125851 0.6851327757316569 0.6549073420257889 1.0251468294540094 0.8131731385896342 0.7427332833936563 0.9882848431087522 1.0 12.753113212089291 -5.5135304926864555 24.566202740972813 0.8286511206894104 1.00947956955187 0.19858386283868423 0.1305784151028741 472.8195636133991 1242515.972495784 0.03479224778762672 0.0648884957294981 3.0652754527338626e-06 5.5135304926864555 0.18082844886245952 S(ph)CSPSPVSPQVQPQAADTISDSVAVPASLLGMR ddPTM_PC-9_AZD4547_30min_R2 1 SCSPSPVSPQVQPQAADTISDSVAVPASLLGMR 33 0 Q9NQW6;Q9NQW6-2;C9JJT6 Q9NQW6 ANLN Actin-binding protein anillin 1 S(0.34)CS(0.34)PS(0.151)PVS(0.169)PQVQPQAADTISDSVAVPASLLGMR 51.018 0.0033486999999999996 5337300.0 3903.6 3865.1 5275.1 10150.0 6805.3 5956.2 6419.0 6776.3 5293.1 6139.9 True False 5144.863600075979 5114.417988849978 5205.148727310891 7810.07431593678 5860.501563028652 5583.75787242617 6990.2785647492865 5729.17853888305 5572.882459922184 5924.943969840111 0.8683396208073875 0.863201072429381 0.8785144220446284 1.3181684680382793 0.9891235415660482 0.9424153039841914 1.1798050074957795 0.9669591084821105 0.9405797739674782 1.0 12.53258579566606 -5.569781771215513 24.999997245474624 1.0494670034888558 0.8670392535590571 0.34727853904386774 0.11198984811106771 127.08478693525423 67737.4338575376 0.030428144976622506 0.05270311961759887 2.6928876140404194e-06 5.569781771215513 -0.1824277499297987 S(ph)CSPSPVSPQVQPQAADTISDSVAVPASLLGMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SCSPSPVSPQVQPQAADTISDSVAVPASLLGMR 33 0 Q9NQW6;Q9NQW6-2;C9JJT6 Q9NQW6 ANLN Actin-binding protein anillin 1 S(0.338)CS(0.338)PS(0.113)PVS(0.208)PQVQPQAADT(0.002)IS(0.001)DS(0.001)VAVPASLLGMR 46.364 0.008776299999999999 3762600.0 3657.2 4354.9 6975.2 6704.5 6134.1 6724.4 7538.9 3600.9 5733.5 5139.1 True False 4276.291727007445 4787.225691468555 7141.515221593309 6328.868601282274 4932.167139005294 6371.760626370343 6824.760815090587 3506.380190468924 5817.341590783663 6070.778148906787 0.7044058639793171 0.7885687096522591 1.176375589162213 1.0425135700967698 0.8124439763778007 1.0495788958319547 1.1241986855209947 0.577583318721727 0.9582530357877167 1.0 12.567665736829483 -10.481017817137598 17.907077370716355 0.9999999981330806 0.9197949316844483 0.01856432472533953 0.182549468143994 0.0 0.0 0.181086710623911 0.04391997854694382 3.303559877473421e-11 10.481017817137598 -0.08020506644863235 S(ph)CSVTDAVAEQGHLPPPSAPAGR ddPTM_PC-9_AZD4547_30min_R2 2 SCSVTDAVAEQGHLPPPSAPAGR 23 0 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 S(0.491)CS(0.491)VT(0.018)DAVAEQGHLPPPSAPAGR;S(0.557)CS(0.424)VT(0.019)DAVAEQGHLPPPSAPAGR 173.36 2.7449e-14 63538000.0 47388.0 31323.5 50769.0 56529.0 65478.0 54729.0 52672.0 61517.0 58337.0 57517.0 True False 62456.39826836781 41448.20881057211 50095.76988812469 43497.112414343836 56387.509932551104 51306.78697827675 57359.7059608155 52010.961170029186 61420.57472265403 55503.34733681229 1.125272641474435 0.7467695337193081 0.9025720482068826 0.7836844893406026 1.0159298968109696 0.9243908600130106 1.0334458859343785 0.9370779181012242 1.1066102797356363 1.0 15.760287160752648 -6.289612294839098 24.815013249448395 0.9973639714326483 0.8803026771905206 0.21562124889816914 0.10498579777331074 963.3725139082321 848546.352208937 0.030810378483362693 0.034942841556990456 5.133194321460049e-07 6.289612294839098 -0.11706129424212774 S(ph)CSVTDAVAEQGHLPPPSAPAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SCSVTDAVAEQGHLPPPSAPAGR 23 0 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 S(0.482)CS(0.482)VT(0.035)DAVAEQGHLPPPSAPAGR;S(0.486)CS(0.486)VT(0.029)DAVAEQGHLPPPSAPAGR 164.48 6.9542e-10 32529000.0 112588.0 109518.0 103527.0 105066.0 147893.0 107248.0 129165.0 133890.0 116396.0 111153.0 True False 131646.92468563744 120390.2232607532 105995.47630833372 99179.49264856773 118914.42830878354 101623.72608068632 116929.55612638126 130375.52936818109 118098.07130040223 131304.15901333615 1.0026104707945045 0.9168805022278507 0.8072514770653083 0.7553415930906985 0.9056409880871007 0.7739566426861217 0.8905243901261733 0.9929276448504518 0.8994236906723372 1.0 17.002553088252434 -7.5833023684421885 5.97462402150646 0.9580158187480129 0.8557077292498908 0.28523772269354064 0.07306017837552725 0.2783645418967935 19.669627172280954 0.036399907113100295 0.020803974531802237 2.61034332469108e-08 7.5833023684421885 -0.10230808949812209 S(ph)CSVTDAVAEQGHLPPPSAPAGR ddPTM_PC-9_Lapatinib_30min_R1 2 SCSVTDAVAEQGHLPPPSAPAGR 23 0 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 S(0.482)CS(0.482)VT(0.036)DAVAEQGHLPPPSAPAGR;S(0.537)CS(0.425)VT(0.037)DAVAEQGHLPPPSAPAGR 161.04 1.2181e-08 44679000.0 124712.0 127243.0 145589.0 136630.0 145229.0 167283.0 153538.0 140819.0 208582.0 162416.0 True False 122933.58401062041 126948.37665128657 133619.2344097923 146678.22598431868 136686.91575119976 160128.69604571932 161487.44637279608 147361.96482503356 185089.29869416612 190489.3891942832 0.6453565971868306 0.666432798111447 0.701452374722625 0.7700073300918572 0.7175565858515646 0.8406174051112185 0.8477503500632911 0.7735967102857194 0.9716514892353955 1.0 17.53935111213896 -6.51472374491762 0.19469814630649276 1.060728354336854 0.47556213837259215 0.8490326392878567 0.04477957128113337 2.4312652216030672 0.19728301043024454 0.14412687577836095 0.40427911427785096 3.0568649692638027e-07 6.51472374491762 -0.5851662159642619 S(ph)CTKPSPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SCTKPSPSK 9 1 Q9NQW6;Q9NQW6-2;C9JJT6 Q9NQW6 ANLN Actin-binding protein anillin 1 S(0.49)CT(0.49)KPS(0.015)PS(0.004)K 59.067 0.035742 198290000.0 35263.0 30635.0 31553.0 35014.0 66084.0 47882.0 42041.0 50911.0 61234.0 48983.0 True False 41232.32942400289 33676.24034033827 32305.34318541887 33052.279096919614 53135.31458796332 45370.98362855643 38058.57212951806 49574.640194663356 62129.431406653384 57863.23015078535 0.712582573018407 0.5819972416434688 0.5583052156133459 0.5712138608713847 0.9182915376396792 0.7841073426133407 0.6577332794996326 0.8567554916218327 1.0737290546129343 1.0 15.820359241918998 -7.5087449150913566 0.5164263626577921 1.0393359000262055 0.600962100715982 0.612884049795059 0.10962173070826987 0.6508310529696804 0.37933617114020274 0.116090200314447 0.08708371685014976 3.099239117411979e-08 7.5087449150913566 -0.43837379931022347 S(ph)CTPSPDQISHR ddPTM_PC-9_AZD4547_30min_R2 1 SCTPSPDQISHR 12 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 S(0.51)CT(0.385)PS(0.105)PDQISHR 90.725 0.0038491 14175000.0 4973.7 5100.2 15975.0 17979.0 14909.0 14566.0 12264.0 14938.0 14735.0 17403.0 True False 6555.233140613254 6748.739910153077 15763.161062120424 13834.219322781006 12839.142698072708 13655.185717363354 13355.472241483922 12629.675341091011 15513.862017901292 16793.72626706094 0.3903382153769308 0.40186077841401957 0.9386339167048435 0.8237730627963917 0.7645201841389593 0.8131123194586367 0.7952655669801657 0.7520472312248377 0.9237891443026577 1.0 14.035634756968825 -5.252601075100788 24.999300530528515 0.8350765233496731 0.39609942009962823 0.8461288269195615 0.07741277753513372 221.05919147944894 625266.4653695376 0.019091154272731708 0.048917250906221864 5.5898341797251015e-06 5.252601075100788 -0.43897710325004485 S(ph)CTPSPDQISHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SCTPSPDQISHR 12 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 S(0.406)CT(0.274)PS(0.32)PDQISHR;S(0.432)CT(0.432)PS(0.135)PDQISHR 115.24 0.00073184 7399300.0 37178.0 37539.0 41827.0 35867.0 41790.0 42003.0 41836.0 33158.0 31917.0 32139.0 True False 43471.50110102883 41265.62383339184 42824.31430978084 33857.48827238291 33601.54949202509 39800.28873794445 37872.99121358951 32287.63763380504 32383.725743968305 37965.546287816 1.1450250385302585 1.0869229569504417 1.1279783513486312 0.8917951032683687 0.8850537599878705 1.048326512575884 0.997562129791974 0.8504457538693936 0.8529766830817596 1.0 15.212403146867176 -5.7560330629892285 24.9996870363188 0.9316611607827605 1.1166702500679813 0.643301079472332 0.06402301715149136 90.34740020936547 417775.08015001967 0.01894249456524415 0.0316328712583991 1.7537469833945574e-06 5.7560330629892285 0.18500908928522075 S(ph)CVALVLLAAAVSCAVAQHAPPVS(ph)ELEPRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SCVALVLLAAAVSCAVAQHAPPVSELEPRR 30 1 A0A1B0GW30;A0A1B0GVA8;A0A1B0GTA6 A0A1B0GW30 2 S(0.992)CVALVLLAAAVS(0.009)CAVAQHAPPVS(0.999)ELEPRR 42.138999999999996 0.038072 5561100.0 8357.1 6771.2 7551.2 9678.8 11551.0 13172.0 10656.0 10604.0 10420.0 9301.7 True False 9771.791969751142 7443.399986698167 7731.24924608547 9136.528215092972 9287.664469547306 12481.237132019243 9646.586537240884 10325.656235866722 10572.372787296736 10988.024577783322 0.8893128970159677 0.6774102054474805 0.7036068395512398 0.8314987057424418 0.8452533395607821 1.1358945407944432 0.87791817982873 0.9397190698630359 0.9621722915211718 1.0 13.423644422069527 -6.3818098651330954 2.6333304947566507 0.9727427811925577 0.7583453846145713 0.5596736186278057 0.08539577865772037 0.20925476909773294 2.824085042097229 0.028451263822307636 0.03315771339281132 4.151357499968744e-07 6.3818098651330954 -0.2143973965779864 S(ph)CVEEPEPEPEAAEGDGDKK ddPTM_PC-9_AZD4547_30min_R2 1 SCVEEPEPEPEAAEGDGDKK 20 1 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 S(1)CVEEPEPEPEAAEGDGDKK 65.438 0.0029506999999999997 3864500.0 12595.0 12920.0 12586.0 12701.0 12668.0 20308.0 16680.0 19825.0 14793.0 12145.0 True False 16599.94800772542 17096.137335629537 12419.10141645369 9772.980678493888 10909.266865596954 19038.137549650888 18164.487686558372 16761.501783179094 15574.927779491945 11719.8072466503 1.4164011112443797 1.4587387809228582 1.0596677193648607 0.8338857860727322 0.9308401269752102 1.6244411831169219 1.5498964534378379 1.4301857897850485 1.3289406089800238 1.0 13.516661221784993 -6.762002212989835 24.999996208886053 1.4237796299494025 1.1361607278464272 0.20406668414502815 0.23806817555171703 23.72891911155697 1053959.5031916264 0.08797681017361689 0.08230963551604213 1.7298075447898063e-07 6.762002212989835 -0.28761890210297536 S(ph)CVSAGMGTGHK ddPTM_PC-9_Lapatinib_30min_R1 1 SCVSAGMGTGHK 12 0 Q68CL5-5 Q68CL5-5 1 S(0.997)CVS(0.003)AGMGTGHK 88.338 0.028107 0.0 13321.0 9714.9 11594.0 12776.0 17191.0 8092.3 13171.0 10385.0 12768.0 12791.0 True False 13131.04009722778 9692.405745931683 10640.786074134237 13715.58965948662 16179.859178806399 7746.211193072651 13852.929933802057 10867.52501230642 11329.933386999426 15001.907307063831 0.8752913765201622 0.6460782317570977 0.7092955486482637 0.9142563927873669 1.0785201406482436 0.5163484238717602 0.9234112470005221 0.7244095560562032 0.75523286173516 1.0 13.872858312771612 -11.737848363680408 2.283100068387191 1.6427993990767455 0.7923779655105142 0.14210140031386054 0.15207699515597062 11653387.762137 2174845.380992084 38709436.542275205 0.037529150664912504 1.8287386188853025e-12 11.737848363680408 -0.8504214335662313 S(ph)DASDMNSDTSPSCR ddPTM_PC-9_AZD4547_30min_R2 3 SDASDMNSDTSPSCR 15 0 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 S(0.999)DAS(0.001)DMNSDTSPSCR;S(0.99)DAS(0.01)DMNSDTSPSCR;S(1)DASDMNSDTSPSCR 171.15 1.2926999999999999e-09 4750700.0 28360.6 27757.5 32029.9 37624.3 33542.4 36450.3 28349.5 36429.5 24400.9 30280.8 True False 37378.68086287394 36729.56904750286 31605.162598035116 28950.5989246404 28885.616743969018 34171.056978828055 30872.550579741408 30800.157841630393 25690.681758575338 29220.67840875821 1.279185936068841 1.2569718106371561 1.08160262934081 0.9907572479892575 0.9885334056895556 1.1694135399876988 1.0565309315504492 1.054053482632312 0.8791952534159906 1.0 14.834702052748682 -5.309042895341261 3.117346075758456 1.0286741859522273 1.277454066454651 0.6667507390922796 0.06905090801770912 0.15449632135649152 2.9786844713581053 0.019334786599541708 0.05172918984534568 4.908593914910365e-06 5.309042895341261 0.24877988050242372 S(ph)DASDMNSDTSPSCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SDASDMNSDTSPSCR 15 0 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 S(0.999)DAS(0.001)DMNSDTSPSCR;S(0.897)DAS(0.103)DMNSDTSPSCR 153.79 2.3621e-10 6931200.0 13878.2 14725.1 15857.7 14173.2 17295.8 12514.9 13933.0 9003.2 12376.900000000001 12794.6 True False 16227.505153055534 16186.91061320435 16235.80770866215 13379.121554134374 13906.812148939169 11858.596612777685 12613.165373815433 8766.875539678917 12557.88874770565 15114.159698002126 1.073662411758199 1.0709765502440753 1.0742117347620914 0.8852044586972904 0.9201181161780002 0.7846017806960992 0.8345264060881077 0.580043860515631 0.8308691319018962 1.0 13.883613151222667 -6.089331428530218 1.0737253846150612 0.7790429540188765 1.0912985239920268 0.5316273187493473 0.10261684903333458 0.36820057699687003 0.8728609543741729 0.04132817786835943 0.07626646737757832 8.1408278581986e-07 6.089331428530218 0.3122555699731503 S(ph)DASDMNSDTSPSCR ddPTM_PC-9_Lapatinib_30min_R1 3 SDASDMNSDTSPSCR 15 0 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 S(0.912)DAS(0.088)DMNSDTSPSCR;S(0.976)DAS(0.024)DMNSDTSPSCR;S(0.997)DAS(0.003)DMNSDTSPSCR 165.24 1.8965e-20 3238800.0 21151.9 23997.3 25146.1 26329.8 27211.8 26965.2 22739.9 22981.1 30628.0 22939.8 True False 20850.270027216615 23941.735726239705 23078.684724753042 28266.181325637972 25611.25542445722 25811.96125495136 23917.26075481476 24048.88580263024 27178.352112861732 26904.913864637867 0.774961411588866 0.8898647974378845 0.8577869767903706 1.0505954959695771 0.9519173914962444 0.9593772120890148 0.8889551133724353 0.8938473441551726 1.0101631341248505 1.0 14.715582067599943 -4.872724951117797 1.3173107955419197 0.9534203725378235 0.7276319702337256 0.5160740835112918 0.05433906743747786 0.9959288790559347 1.7252525494182238 0.016525117886813195 0.2909632411939306 1.3405254048234955e-05 4.872724951117797 -0.2257884023040979 S(ph)DDEQSSADK ddPTM_PC-9_Lapatinib_30min_R1 1 SDDEQSSADK 10 0 A6NGV6;P27540-3;P27540-4;P27540 A6NGV6 ARNT Aryl hydrocarbon receptor nuclear translocator 1 S(1)DDEQSSADK 70.256 0.03625 2578600.0 3644.7 3503.5 1603.9 2749.4 3156.4 2974.3 1312.0 1239.7 1496.8 1638.0 True False 3592.7259096438775 3495.3878610044 1472.0335332330428 2951.600047729532 2970.7467577211637 2847.09612243194 1379.9289403346968 1297.3009877473532 1328.2146219972396 1921.1261175021941 1.8701145525599645 1.8194473695194078 0.7662347202623784 1.536390568448019 1.5463569677474704 1.481993345722493 0.718291697647029 0.6752815319767114 0.691372945220356 1.0 10.907736516379002 -7.2598635736266175 23.44881666913158 0.744176602899882 1.4877292468344099 0.5995844710671605 0.29262573988936463 43.47833608909638 646992.8732125978 0.12124457922324582 0.08877733045524837 5.4971353008141965e-08 7.2598635736266175 0.7435526439345279 S(ph)DEDRYQNGAER ddPTM_PC-9_AZD4547_30min_R2 1 SDEDRYQNGAER 12 1 Q9HCG8 Q9HCG8 CWC22 Pre-mRNA-splicing factor CWC22 homolog 1 S(1)DEDRYQNGAER 77.204 0.008407600000000001 21910000.0 8636.2 12615.0 11638.0 24495.0 18461.0 18260.0 17265.0 14829.0 19039.0 16220.0 True False 11382.331955880767 16692.552050229613 11483.672515865883 18848.056193977463 15898.008810055686 17118.19931340482 18801.551553263213 12537.518786520195 20045.36267111115 15652.142736983758 0.7272059900773813 1.0664707274095782 0.7336805387502389 1.2041837664463806 1.015708141511576 1.0936649122779198 1.2012126307050506 0.8010097401486024 1.2806784992924225 1.0 13.9340725513664 -5.7624440822180665 24.999988397300104 1.0792070165227805 0.8648542578252859 0.34095885015091465 0.1535600340385017 31.873795930709182 793154.3319381364 0.03974566175150402 0.06296732854458525 1.7280484618439643e-06 5.7624440822180665 -0.2143527586974946 S(ph)DGSENLCTPQQSR ddPTM_PC-9_AZD4547_30min_R2 1 SDGSENLCTPQQSR 14 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 S(0.967)DGS(0.033)ENLCTPQQSR 110.38 0.00049995 3766900.0 7647.4 10096.0 11462.0 16433.0 14547.0 12791.0 8397.0 12906.0 8740.5 9702.3 True False 10079.114124198442 13359.334561959426 11310.006390862245 12644.625737319118 12527.400149497858 11991.17674796063 9144.316732855556 10911.674250376269 9202.504985915593 9362.625430150276 1.0765264721304424 1.4268791015539966 1.2079951799033695 1.3505427330885076 1.33802214378417 1.2807493835378356 0.9766829615343037 1.165450260910537 0.9828979119767998 1.0 13.192697426003157 -7.249564814609276 23.851563449620343 1.0450453120077337 1.289344764534341 0.5907826775701734 0.10103255965995617 272.0197294490275 546386.8939583743 0.036300710762074376 0.027865743161444415 5.629051025185593e-08 7.249564814609276 0.24429945252660734 S(ph)DGSENLCTPQQSR ddPTM_PC-9_Lapatinib_30min_R1 1 SDGSENLCTPQQSR 14 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 S(0.964)DGS(0.036)ENLCTPQQSR 118.08 0.0015924000000000001 0.0 7664.9 8562.0 9526.8 8081.3 9647.0 9178.0 8958.9 6521.2 6860.7 9982.5 True False 7555.597120429487 8542.175215047708 8743.543278511472 8675.625760426516 9079.582426731738 8785.478334962974 9422.748005765641 6824.198758811037 6087.975719626175 11707.961824154858 0.6453383803183771 0.7296039518530226 0.7468031934023347 0.7410022248729674 0.7755049566355372 0.7503849488847437 0.8048154023124195 0.5828682106506308 0.519985955801973 1.0 13.515202326258404 -7.752933495682914 24.979389409696807 0.663570303595213 0.7432176229378505 0.0 0.1244933054374365 474.06843317448084 1392216.000425283 0.056452451575958566 0.03191454354967492 1.7663082780305892e-08 7.752933495682914 0.07964731934263758 S(ph)DISPLTPR ddPTM_PC-9_AZD4547_30min_R2 2 SDISPLTPR 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.935)DIS(0.065)PLTPR;S(0.976)DIS(0.024)PLTPR 102.95 0.0030111 9342200.0 35094.0 44347.0 105329.0 134293.0 99698.0 86666.0 59392.0 135270.0 75384.0 84006.0 True False 46253.16199945344 58681.30049714883 103932.268639254 103333.82365616711 85856.65361274757 81246.76131958082 64677.772942450545 114367.12969536617 79368.64434051374 81064.97550943619 0.5705689998520933 0.7238798276120884 1.282085980858108 1.2747036930164588 1.0591091044338083 1.002242470425757 0.7978510143992071 1.4108081693314458 0.979074425690476 1.0 16.306791105668218 -5.107916190865091 4.862637669682656 1.1046071060216573 0.6039795111805824 0.5376862714103412 0.17042496033698437 0.15759597006497136 5.618016498936327 0.0445787050070363 0.13000802304728024 7.79980614838367e-06 5.107916190865091 -0.500627594841075 S(ph)DISPLTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SDISPLTPR 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.784)DIS(0.216)PLTPR;S(0.937)DIS(0.063)PLTPR;S(1)DISPLTPR;S(0.997)DIS(0.003)PLTPR;S(0.795)DIS(0.205)PLTPR;S(0.522)DIS(0.478)PLTPR 109.79 0.0023452 110895000.0 121058.0 145720.0 144734.0 149811.0 150716.0 133449.0 131498.0 120110.0 117246.0 101042.0 True False 141550.7283955118 160186.11857007007 148185.00746675133 141417.57536381492 121184.2817238589 126450.6995164618 119041.55747692427 116957.23976706454 118960.50094235988 119360.11475196824 1.1859131393234326 1.3420405878709045 1.241495182663669 1.184797582154494 1.0152828855407965 1.0594049761030129 0.9973311245912763 0.9798686940784457 0.9966520322937125 1.0 16.864961302140053 -6.132152205851967 1.9072374474107958 1.003109090554012 1.2690948796282064 0.8868902861667497 0.04086693016475625 0.09986891894496724 0.7178722672026432 0.013389503201450804 0.019373625236768565 7.376456644140407e-07 6.132152205851967 0.26598578907419435 S(ph)DISPLTPR ddPTM_PC-9_Lapatinib_30min_R1 5 SDISPLTPR 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.994)DIS(0.006)PLTPR;S(0.994)DIS(0.006)PLTPR;S(0.989)DIS(0.011)PLTPR;S(0.793)DIS(0.207)PLTPR;S(1)DISPLTPR 134.57 0.0011079 38568900.0 185247.0 167058.0 186328.0 124899.0 187373.0 160287.0 145890.0 165601.0 180742.0 127454.0 True False 182605.34380986085 166671.18746501295 171008.83108687957 134084.48911084983 176352.08852949142 153431.89865724673 153443.47035474746 173295.42701617276 160384.9326623632 149484.25407821988 1.2215690872318221 1.1149748747302826 1.1439922695630313 0.8969806882849889 1.1797368867841596 1.0264084307967392 1.026485841608815 1.1592888367057934 1.0729219184412517 1.0 17.18963400060167 -4.821636047588026 1.551845577001471 1.0633146409696173 1.2674240583791583 0.27883009329720065 0.07925375816725257 1.3525729131747506 3.2953723202526057 0.02182039577897969 0.41584077014006654 1.5078701794035586e-05 4.821636047588026 0.20410941740954103 S(ph)DKGSPGEDGFVPSALGTR ddPTM_PC-9_Lapatinib_30min_R1 1 SDKGSPGEDGFVPSALGTR 19 1 G3V238;A0A494BZY7;Q5JPI9 G3V238 METTL10 Protein-lysine N-methyltransferase METTL10 1 S(0.534)DKGS(0.466)PGEDGFVPSALGTR 47.05 0.038631 10647000.0 16993.0 16249.0 18558.0 16722.0 20193.0 17988.0 19948.0 14773.0 20019.0 21864.0 True False 16750.67670386545 16211.376438835587 17032.23287595163 17951.791662956737 19005.28744096549 17218.695172076037 20980.80983368637 15459.40751148798 17764.249410584398 25643.163268051274 0.6532219340012182 0.6321909769623969 0.6642017093566623 0.7000615125093717 0.741144422874073 0.6714731327054626 0.8181833736490024 0.6028666334916957 0.6927479743779043 1.0 14.6462866192612 -11.778741060421519 2.08032435900544 2.066196170629395 0.687011652172178 0.7326619611341662 0.05685838259083692 3969308.97501773 604782.7520641781 19892486.106973622 0.014524824508122884 1.664404723304989e-12 11.778741060421519 -1.3791845184572171 S(ph)DKSPDLAPTPAPQSTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDKSPDLAPTPAPQSTPR 18 1 F8WAE5;Q9BY44-3;Q9BY44;Q9BY44-2;Q9BY44-4 F8WAE5 EIF2A Eukaryotic translation initiation factor 2A;Eukaryotic translation initiation factor 2A, N-terminally processed 1 S(0.536)DKS(0.428)PDLAPT(0.013)PAPQS(0.011)T(0.011)PR 84.70700000000001 0.00090514 113690000.0 64624.0 55772.0 49658.0 52445.0 69797.0 57937.0 65188.0 57016.0 57673.0 43675.0 True False 75563.56681781923 61308.67557569267 50842.03504901375 49506.67667898411 56120.77889195683 54898.681727740564 59012.92071975031 55519.390413445566 58516.35851840348 51592.9317688902 1.4646108338309818 1.1883154043333688 0.9854457443271477 0.9595631607203204 1.0877609968619162 1.0640736985767434 1.1438179358385339 1.076104584677294 1.1341933189710303 1.0 15.654885809530281 -4.835962607454853 2.9646933746177155 1.0607120062754025 1.5067843481764491 0.8194604661232331 0.058198398552104194 0.1443912734613912 1.9731056937318319 0.016072990140227623 0.14579671018562756 1.4589398688859588e-05 4.835962607454853 0.4460723419010466 S(ph)DKSPDLAPTPAPQSTPR ddPTM_PC-9_Lapatinib_30min_R1 1 SDKSPDLAPTPAPQSTPR 18 1 F8WAE5;Q9BY44-3;Q9BY44;Q9BY44-2;Q9BY44-4 F8WAE5 EIF2A Eukaryotic translation initiation factor 2A;Eukaryotic translation initiation factor 2A, N-terminally processed 1 S(0.5)DKS(0.5)PDLAPTPAPQSTPR 93.851 0.00046917 551860000.0 42942.0 32941.0 39524.0 43634.0 43330.0 41115.0 46738.0 39599.0 37397.0 32527.0 True False 42329.639205401676 32864.72713838899 36274.48928705204 46842.989918757 40781.414590057655 39356.607293746194 49157.864949209645 41438.91410325679 33184.95605213173 38149.24861049686 1.109579893370549 0.8614777049460989 0.9508572411848506 1.227887615743709 1.0689965353298347 1.0316482952410528 1.2885670554382487 1.0862314622850728 0.8698718129667384 1.0 15.219367021495614 -5.690547559755503 24.999842918350705 1.0914642685776748 0.962720877349173 0.13434172507919584 0.12288148460459632 80.45286031033878 28369.49011359613 0.03331256589496128 0.05769904472069317 2.0391653376015415e-06 5.690547559755503 -0.12874339122850176 S(ph)DLAEELK ddPTM_PC-9_Lapatinib_30min_R1 1 SDLAEELK 8 0 D6RB49;A0A1W2PR94;Q6ZMT9-2;Q6ZMT9 D6RB49 DTHD1 Death domain-containing protein 1 1 S(1)DLAEELK 69.812 0.039847 3569400.0 13805.0 16186.0 13611.0 13456.0 16191.0 13534.0 11790.0 13366.0 17445.0 13933.0 True False 13608.138168473059 16148.522311464867 12491.956119979384 14445.599127900115 15238.677212730754 12955.182369294927 12400.428511086953 13987.033154981948 15480.160396006047 16341.300485444483 0.8327451160080004 0.9882030090474545 0.7644407573990953 0.8839932379168411 0.9325253657935085 0.7927877209549119 0.7588397583247587 0.8559314582973658 0.9473028422550904 1.0 13.99623518122416 -8.401852817821295 3.1540599181536066 0.9972188391417862 0.8515042401122472 0.3528335550721573 0.06810823942858334 0.27392104456171057 5.0267253472323645 0.06662310490112172 0.01787629004016767 3.964123554388054e-09 8.401852817821295 -0.14571459902953898 S(ph)DSASSEPVGIYQGFEK ddPTM_PC-9_AZD4547_30min_R2 1 SDSASSEPVGIYQGFEK 17 0 Q05655;Q05655-2 Q05655 PRKCD Protein kinase C delta type;Protein kinase C delta type regulatory subunit;Protein kinase C delta type catalytic subunit 1 S(0.754)DS(0.226)AS(0.02)SEPVGIYQGFEK 170.48 1.3800000000000002e-05 5218000.0 12249.0 20616.0 21314.0 24737.0 25045.0 26254.0 24273.0 36709.0 24052.0 22325.0 True False 16143.927204972493 27279.71883214692 21031.362433679806 19034.266832840192 21567.934058168285 24612.333229689495 26433.2499769683 31036.46753890147 25323.33961686882 21543.40854520115 0.7493673608380135 1.2662675349126007 0.9762318896544622 0.8835308856954358 1.0011384230548142 1.142453069951735 1.22697621973364 1.4406479584594298 1.1754565004760893 1.0 14.394958907157713 -6.933048854628096 2.6414244226832806 1.2452910847596426 0.9850576907235087 0.3283761096814506 0.15770227337351356 0.30728095003394124 4.348452890021552 0.061506110041284874 0.051448862866069846 1.1666783677678046e-07 6.933048854628096 -0.2602333940361339 S(ph)DSASSEPVGIYQGFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SDSASSEPVGIYQGFEK 17 0 Q05655;Q05655-2 Q05655 PRKCD Protein kinase C delta type;Protein kinase C delta type regulatory subunit;Protein kinase C delta type catalytic subunit 1 S(0.509)DS(0.298)AS(0.149)S(0.044)EPVGIYQGFEK;S(0.973)DS(0.015)AS(0.012)SEPVGIYQGFEK 248.97 3.3871999999999993e-131 4464300.0 33890.0 45821.0 35180.0 30774.0 35624.0 24436.0 30980.0 24592.0 21114.8 23068.0 True False 39626.90764198899 50369.80605956064 36018.82462089294 29049.832550654126 28643.732929023754 23154.533142880526 28045.350124223223 23946.486057377817 21423.56400472293 27250.045793812467 1.4541960017911923 1.8484301435925607 1.3217895079307191 1.0660471094419346 1.0511443960775928 0.849706210333713 1.029185430968756 0.8787686537692068 0.7861845138472198 1.0 14.733971033895918 -5.653165390808161 1.99161457611388 0.9317226578860806 1.6580757644258923 0.8396229840818128 0.12377531646314775 0.11385006342262721 0.9102789734432088 0.035784215970863245 0.07948575496481801 2.2224633567302516e-06 5.653165390808161 0.7263531065398118 S(ph)DSDLLTCSPTEDATMGSR ddPTM_PC-9_AZD4547_30min_R2 2 SDSDLLTCSPTEDATMGSR 19 0 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 S(0.745)DS(0.254)DLLTCSPTEDATMGSR;S(0.761)DS(0.236)DLLT(0.003)CSPTEDATMGSR 96.15299999999999 0.00059257 11470500.0 29617.9 42386.0 45228.0 36617.0 48797.0 60411.0 52521.0 66316.0 62148.0 49528.0 True False 39035.77610940936 56086.445596593876 44628.247168549766 28175.51637701052 42022.37884753196 56633.49062004927 57195.267253341255 56068.38599007843 65433.01640234338 47794.03979514992 0.8167498766942622 1.1735029270801558 0.9337617694555836 0.5895194567727196 0.8792388973111317 1.1849488108305164 1.1967029256887667 1.1731250639283308 1.3690622655627334 1.0 15.544543096204928 -6.767057863734299 7.818405963276334 1.1969750378130488 0.8815637260876092 0.4866369453643048 0.15700889430011575 0.11754259384703765 49.83838973675446 0.05685345658423602 0.05274970474951527 1.7097874943729249e-07 6.767057863734299 -0.31541131172543957 S(ph)DSDLLTCSPTEDATMGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDSDLLTCSPTEDATMGSR 19 0 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 S(0.848)DS(0.15)DLLT(0.002)CSPTEDATMGSR 117.29 5.5258999999999994e-05 4539100.0 10311.0 16169.0 15701.0 11291.0 13680.0 9214.9 12314.0 8162.9 8147.9 9799.5 True False 12056.448648467067 17774.15146280168 16075.371386374094 10658.401875915897 10999.502202701688 8731.654422095662 11147.52877436039 7948.632524307474 8267.04762318762 11576.071777200677 1.041497399161994 1.535421670225668 1.3886724007737137 0.9207270031711318 0.9501929855311924 0.754284751351736 0.962980274216655 0.6866433343962567 0.7141496513065639 1.0 13.498858151961098 -5.829117601449087 4.488527004181229 0.8395043983940845 1.344495956252479 0.6635440112747419 0.1523300452825284 0.1149011051273499 4.475626248061455 0.043094707438123596 0.06720022550313058 1.4821166923603597e-06 5.829117601449087 0.5049915578583944 S(ph)DSDLLTCSPTEDATMGSR ddPTM_PC-9_Lapatinib_30min_R1 5 SDSDLLTCSPTEDATMGSR 19 0 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 S(0.394)DS(0.054)DLLT(0.191)CS(0.331)PT(0.018)EDAT(0.006)MGS(0.006)R;S(0.771)DS(0.226)DLLT(0.002)CS(0.001)PT(0.001)EDATMGSR;S(0.995)DS(0.005)DLLTCSPTEDATMGSR;S(0.96)DS(0.04)DLLTCSPTEDATMGSR;S(0.982)DS(0.018)DLLTCSPTEDATMGSR 126.91 3.1732e-05 10765100.0 20254.3 31607.38 30690.100000000002 24938.69 31319.9 29689.9 25311.100000000002 28829.1 32899.3 21426.649999999998 True False 19965.469967816283 31534.195053561656 28166.87844521192 26772.764455631062 29477.725059292556 28420.13218753726 26621.584909836536 30168.605231803827 29193.83438901243 25130.2179032835 0.794480574925998 1.2548317398171631 1.1208370159628283 1.0653614130473954 1.1729991826072075 1.1309146739958789 1.0593455660548878 1.2004911914377796 1.1617023975426006 1.0 14.617135560382962 -4.748314704824049 24.997659511753753 1.1327937004351598 0.7944797615387811 0.6703997477715224 0.07046337407039602 371.8618288931971 708217.8947756537 0.016700235958986617 0.3116835017131499 1.7851934930024426e-05 4.748314704824049 -0.33831393889637873 S(ph)DSEATISR ddPTM_PC-9_AZD4547_30min_R2 1 SDSEATISR 9 0 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79;H0Y4T4 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 S(0.998)DS(0.002)EATISR 97.45200000000001 0.0047791000000000005 24237000.0 6339.4 6345.6 13553.0 18964.0 18555.0 18323.0 10785.0 11449.0 11245.0 15526.0 True False 8355.19733228857 8396.691105028693 13373.27836462712 14592.142790879312 15978.95853261379 17177.259913445607 11744.844106686574 9679.820121847042 11839.38774287751 14982.439465746613 0.5576660163647261 0.5604355101334136 0.8925968561529373 0.9739497245585667 1.0665124707592148 1.1464928627088313 0.7839073292128466 0.6460777061023601 0.7902176257708327 1.0 13.87098492448108 -5.2691113853793405 5.6340935354398125 0.9123026745828157 0.5556009053493187 0.5097811311295809 0.13873384255165006 0.14001932363129418 17.540492547836138 0.041895706880249746 0.09906573039737966 5.381317478449756e-06 5.2691113853793405 -0.35670176923349695 S(ph)DSEATISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDSEATISR 9 0 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79;H0Y4T4 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 S(1)DSEATISR 105.4 0.0026389 9994400.0 36166.0 52464.0 45575.0 40604.0 49593.0 34422.0 37212.0 31458.0 24244.0 36550.0 True False 42288.189488939955 57672.27919750311 46661.68084415 38329.08951994412 39875.607656329266 32616.84972353222 33687.009968450424 30632.26083250616 24598.522634858145 43176.2256703592 0.979432287847502 1.3357415638369603 1.080726258946335 0.8877359918529731 0.9235547349777766 0.7554354095829162 0.7802212779237164 0.7094705560040518 0.5697237832380799 1.0 15.39794951256596 -6.046368953055223 1.1337144382579694 0.7448426098240425 1.1747623144959478 0.564583120024515 0.13525200817151678 0.3348305935694762 0.8791343776683924 0.052080759108634155 0.09842782692613304 8.987337416374925e-07 6.046368953055223 0.4299197046719053 S(ph)DSEATISR ddPTM_PC-9_Lapatinib_30min_R1 2 SDSEATISR 9 0 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79;H0Y4T4 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 S(0.997)DS(0.003)EATISR;S(0.997)DS(0.003)EATISR 126.03 0.0014077 38058000.0 117538.0 113424.0 89827.0 105729.0 110554.0 90448.0 98280.0 86403.0 99076.0 90778.0 True False 115861.8865661704 113161.37369674984 82441.77080224734 113504.6633616044 104051.43107752684 86579.74988458613 103368.45751226683 90417.59880965903 87917.01756346769 106468.85634591806 1.088223265869733 1.06285892025634 0.774327569880092 1.0660832402747613 0.9772945314586926 0.8131931989885184 0.9708797582686715 0.8492398802133426 0.8257533759715111 1.0 16.70007195778833 -5.101857914249511 8.883654816201151 0.9110487507102198 1.0819148807962617 0.3584177908580629 0.08906661890631112 0.32524700308392096 25.523606216226003 0.022344001725844064 0.059580101637048966 7.909373523227324e-06 5.101857914249511 0.1708661300860419 S(ph)DSELEVKPAESLLR ddPTM_PC-9_AZD4547_30min_R2 1 SDSELEVKPAESLLR 15 1 Q92539 Q92539 LPIN2 Phosphatidate phosphatase LPIN2 1 S(0.964)DS(0.036)ELEVKPAESLLR 63.145 0.019033 4208100.0 11010.0 11475.0 10400.0 8935.4 10543.0 16194.0 10872.0 13386.0 13575.0 9320.4 True False 14510.95097777347 15184.069344144647 10262.08920476071 6875.481580553842 9079.28643542696 15181.38662000426 11839.586938145234 11317.501279678962 14292.546786088236 8994.095632908973 1.6133863336607832 1.688226361368324 1.1409806637158948 0.7644439042205398 1.0094718586498324 1.687928085226966 1.3163732543408524 1.2583256551407744 1.5891032705714714 1.0 13.134762508716827 -6.740792421331764 24.996054982926474 1.3831183873864088 1.2357322801614692 0.04041815965377005 0.30525476044959027 941.43698525692 1139739.8154420934 0.11037527939250857 0.11025701737573962 1.816383627754222e-07 6.740792421331764 -0.1473861072249396 S(ph)DSELEVKPAESLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SDSELEVKPAESLLR 15 1 Q92539 Q92539 LPIN2 Phosphatidate phosphatase LPIN2 1 S(0.988)DS(0.012)ELEVKPAESLLR;S(0.996)DS(0.004)ELEVKPAESLLR;S(0.999)DS(0.001)ELEVKPAESLLR 79.32600000000001 0.005183600000000001 12030500.0 65946.0 76816.0 56665.0 62354.0 64461.0 54357.4 63577.0 41926.4 51827.0 51042.6 True False 77109.35530712923 84441.78482074177 58016.1085032092 58860.507534395576 51830.3297871603 51506.802253266236 57554.526302380225 40825.8764246928 52584.87182794895 60296.21932700069 1.2788422917355218 1.4004490789512682 0.962184845928301 0.9761890246415135 0.8595950188198722 0.8542293833371648 0.9545296030958158 0.6770884954375728 0.8721089384189865 1.0 15.879779925137788 -5.369345832373626 3.289408563198372 0.8754406982790272 1.3439124531461968 0.7932420004189196 0.09106083551896957 0.10090300712846154 2.0294511178245953 0.024945920919117934 0.060394269673382475 4.272225497290334e-06 5.369345832373626 0.46847175486716963 S(ph)DSELEVKPAESLLR ddPTM_PC-9_Lapatinib_30min_R1 2 SDSELEVKPAESLLR 15 1 Q92539 Q92539 LPIN2 Phosphatidate phosphatase LPIN2 1 S(0.976)DS(0.024)ELEVKPAESLLR;S(0.986)DS(0.014)ELEVKPAESLLR 81.01 0.004368899999999999 9263500.0 20983.0 27380.0 26175.0 20726.0 23229.0 22699.2 22392.2 28602.6 21145.1 23106.6 True False 20683.778572189076 27316.603292222186 24022.992538421895 22250.259179909168 21862.715889971125 21728.40813041964 23551.558550123933 29931.58121492494 18763.516170225696 27100.54502239085 0.7632237121098432 1.007972469544536 0.8864394615891955 0.8210262620742754 0.8067260592695772 0.8017701530529119 0.8690437233149853 1.1044641792331131 0.6923667459352946 1.0 14.726034245637589 -10.475168849863604 5.776563538032992 1.000000115870939 0.8693100178773898 0.11538517546989757 0.11322154207885463 1.6374369994131145e-07 2.9583567869423638e-08 0.1061880992999055 0.02575437400896288 3.348352328630205e-11 10.475168849863604 -0.13069009799354925 S(ph)DSELEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDSELEVR 8 0 Q9BQK8;Q9BQK8-2 Q9BQK8 LPIN3 Phosphatidate phosphatase LPIN3 1 S(1)DSELEVR 112.3 0.0037321999999999998 6594400.0 19849.0 38898.0 27101.0 17387.0 28456.0 16699.0 33740.0 20543.0 21670.0 22095.0 True False 23209.043664380046 42759.53637207372 27747.190621114827 16412.862759414566 22880.251073105184 15823.275043090602 30543.902943553643 20003.76801710769 21986.882754387727 26100.64859607624 0.8892132921121778 1.638255701373714 1.0630843336700113 0.6288296897680138 0.8766161878653397 0.6062406834391596 1.1702353997496202 0.7664088477906597 0.8423883672259799 1.0 14.671798037483166 -5.523101619327839 24.99307169520207 0.8378296763752221 1.2854683904550528 0.35778510408660047 0.22851921898328856 6.643088165097807 744937.3621255715 0.05781197743734318 0.1014230585251509 2.998460835594767e-06 5.523101619327839 0.4476387140798307 S(ph)DSELVSK ddPTM_PC-9_AZD4547_30min_R2 1 SDSELVSK 8 0 Q14693;Q14693-2;Q14693-4;Q14693-3;Q14693-5;Q14693-7;A0A0A0MS66;Q14693-6 Q14693 LPIN1 Phosphatidate phosphatase LPIN1 1 S(1)DSELVSK 89.679 0.027052999999999997 0.0 22408.0 23195.0 26050.0 25245.0 30857.0 36508.0 22725.0 31062.0 29779.0 25289.0 True False 29533.277884645573 30692.330147053162 25704.55997923237 19425.155281361956 26573.038180590876 34225.14898870668 24747.480975841652 26262.08163375076 31353.057144966588 24403.63980737254 1.21019971273807 1.2576947696868055 1.053308448335105 0.7959941809784234 1.0888965084857114 1.4024608320258432 1.0140897493645695 1.0761542885015363 1.2847697061769685 1.0 14.574808721617243 -6.5480100139392 24.997126142643314 1.16189023154232 1.071717622924358 0.04939257997405311 0.16078083315649963 740.9996890764239 737039.3123232778 0.056166518254096964 0.05616847710060439 2.8313267104651304e-07 6.5480100139392 -0.09017260861796217 S(ph)DSELVSK ddPTM_PC-9_Lapatinib_30min_R1 2 SDSELVSK 8 0 Q14693;Q14693-2;Q14693-4;Q14693-3;Q14693-5;Q14693-7;A0A0A0MS66;Q14693-6 Q14693 LPIN1 Phosphatidate phosphatase LPIN1 1 S(0.999)DS(0.001)ELVSK;S(0.989)DS(0.011)ELVSK 119.53 0.0025329000000000003 5899300.0 43455.0 59516.0 46076.0 42352.0 54734.0 51536.0 54717.0 52399.0 53971.0 35834.0 True False 42835.323731328965 59378.19435865217 42287.80913850344 45466.70736213037 51514.65373118428 49331.92541628365 57549.97852766281 54833.64883195414 47892.21764017435 42027.859154196376 1.019212603101435 1.4128293839759716 1.0061851826273933 1.0818230639661464 1.2257263341009523 1.173791061669102 1.3693292898055358 1.3046976442643554 1.1395350275744995 1.0 15.359058348856676 -6.294850938740224 22.56414638710656 1.224352848783724 1.141368956296311 0.04363573317742531 0.14071013010790234 562.377614895565 379793.1534311543 0.04302070975877637 0.04878689792678836 5.071647506527818e-07 6.294850938740224 -0.08298389248741311 S(ph)DSETSK ddPTM_PC-9_AZD4547_30min_R2 1 SDSETSK 7 0 A0A087WTW5;Q9UKL3 A0A087WTW5 CASP8AP2 CASP8-associated protein 2 1 S(1)DSETSK 84.916 0.019635 6022500.0 9010.2 19106.0 17601.0 21740.0 20152.0 16768.0 21149.0 23342.0 17045.0 14703.0 True False 11875.256176197508 25281.640861806325 17367.599239710897 16728.17887965178 17354.24264884038 15719.494309264632 23031.220028958203 19735.030245799066 17945.96390194283 14188.252445244896 0.8369780719666731 1.7818713727693298 1.2240830438234511 1.1790161575013507 1.223141660032737 1.1079232181643992 1.6232598142611265 1.3909415780386074 1.2648466730627779 1.0 13.792409284392678 S(ph)DSETSK ddPTM_PC-9_Lapatinib_30min_R1 1 SDSETSK 7 0 A0A087WTW5;Q9UKL3 A0A087WTW5 CASP8AP2 CASP8-associated protein 2 1 S(1)DSETSK 72.789 0.037944 7540000.0 18054.0 21752.0 32544.0 26144.0 22725.0 23134.0 15427.0 26326.0 26854.0 14412.0 True False 17796.546649301894 21701.6345804389 29868.357943472874 28066.71697382734 21388.360179069 22144.612747987954 16225.734575109269 27549.202067788043 23829.419734843574 16903.094997217115 1.0528572815943988 1.283885263853265 1.767034850622938 1.6604483958972116 1.265351711186048 1.3100921903138916 0.9599268404857593 1.6298318191031689 1.4097666574533714 1.0 14.044999811164784 S(ph)DSLLSFR ddPTM_PC-9_AZD4547_30min_R2 5 SDSLLSFR 8 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 S(0.963)DS(0.034)LLS(0.003)FR;S(0.731)DS(0.269)LLSFR;S(0.976)DS(0.024)LLSFR;S(0.88)DS(0.12)LLSFR;S(0.676)DS(0.324)LLSFR 152.11 0.00027184 42636700.0 55701.2 49844.100000000006 66685.3 88775.4 81319.1 74534.4 67758.0 96544.9 70439.5 74722.4 True False 73413.02294306597 65955.23057049938 65801.00935059898 68309.60309625742 70029.3466348411 69873.75218537998 73788.33073536104 81626.1040860957 74162.78816491058 72106.39151972861 1.0181208821548067 0.9146932633905795 0.9125544624237028 0.9473446341794488 0.9711947187882891 0.9690368733299077 1.0233257992833027 1.1320231447688303 1.0285189232444025 1.0 16.137839525355744 -7.305990874982854 2.7511435563253426 1.0622942091534284 0.9500010123388212 0.5231975125973409 0.042514768298811755 0.1970194258509512 2.9532994060756548 0.01956836396362963 0.012751792408890444 4.943210731212879e-08 7.305990874982854 -0.11229319681460725 S(ph)DSLLSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SDSLLSFR 8 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 S(0.707)DS(0.286)LLS(0.007)FR;S(0.732)DS(0.268)LLSFR;S(0.96)DS(0.04)LLSFR;S(0.679)DS(0.321)LLSFR;S(0.999)DS(0.001)LLSFR 168.25 0.00057266 34285800.0 50534.4 63669.7 73700.0 74324.90000000001 77067.0 69592.1 89248.5 72388.9 67394.7 62634.5 True False 59088.875820104164 69990.40703761173 75457.28750880634 70160.71681757698 61966.27458008847 65942.56776610963 80794.23597681514 70488.76807737937 68380.21998925389 73989.63903557089 0.7986101377207273 0.9459487564733692 1.019835864755738 0.9482505622692234 0.8374993497440618 0.8912405659177146 1.0919668892826049 0.9526843081839005 0.9241864250260737 1.0 16.175035640040555 S(ph)DSLLSFR ddPTM_PC-9_Lapatinib_30min_R1 4 SDSLLSFR 8 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 S(0.561)DS(0.439)LLSFR;S(0.499)DS(0.499)LLS(0.002)FR;S(0.765)DS(0.235)LLSFR;S(0.822)DS(0.178)LLSFR 164.46 0.00014801 33232100.0 45472.899999999994 48472.2 55128.600000000006 49727.9 63100.200000000004 52550.4 47680.9 47464.8 60952.3 46795.1 True False 44824.44810729141 48359.9655990231 50596.13931055002 53385.05565341143 59388.77029576636 50302.94189296554 50149.583697564485 49670.18788677144 54087.210117826224 54883.57068444868 0.8167188750347191 0.881137378562105 0.9218813331488742 0.9726964734191055 1.0820864888186699 0.9165391621871813 0.9137449162318155 0.9050101381404024 0.9854900008018592 1.0 15.744086724784111 -5.113720595319805 1.7337529348488194 0.9631746739353563 0.8120839551985558 0.4882112393618604 0.04975982793247789 0.49443044933318414 2.3001300409641487 0.015386914068848356 0.09975132028007846 7.696254219092885e-06 5.113720595319805 -0.15109071873680047 S(ph)DSNFQVPNGGIPR ddPTM_PC-9_Lapatinib_30min_R1 1 SDSNFQVPNGGIPR 14 0 Q9P270;D6RIF6;H0Y9L2 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 S(0.977)DS(0.023)NFQVPNGGIPR 104.09 0.005019300000000001 0.0 20710.0 19615.0 15325.0 17466.0 16207.0 13153.0 17526.0 15588.0 17789.0 14128.0 True False 20414.671602251132 19569.58267264201 14065.03765621073 18750.50790486797 15253.736124187966 12590.476851140551 18433.410524623403 16312.27538679175 15785.415493525456 16570.005975623317 1.2320256029046597 1.1810244788946649 0.848825140854039 1.1315933097702233 0.9205631033946663 0.7598353838654505 1.1124564802053423 0.9844459567962304 0.952649957806165 1.0 14.016286502386459 -5.138765508803451 5.918316134225721 0.9661461490646911 1.2185365639979218 0.46486605065231745 0.10457859990524275 0.19245727452846112 8.373024454392484 0.02660165814081741 0.0733752504469651 7.26498113993365e-06 5.138765508803451 0.25239041493323067 S(ph)DSPEIPFQAAAGPSDGLDASSPGNSFVGLR ddPTM_PC-9_Lapatinib_30min_R1 1 SDSPEIPFQAAAGPSDGLDASSPGNSFVGLR 31 0 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 S(0.521)DS(0.479)PEIPFQAAAGPSDGLDASSPGNSFVGLR 77.804 6.272699999999999e-07 2217700.0 12310.0 10951.0 11867.0 12128.0 8498.6 13601.0 10984.0 9692.4 13050.0 9519.2 True False 12134.457142622474 10925.643632327432 10891.341067944708 13019.933577821994 7998.729056890466 13019.316935479552 11552.69777487523 10142.744287845806 11580.171577407778 11164.581036463305 1.0868708017785507 0.9785986233289447 0.9755261780423107 1.1661820121417135 0.7164379057993105 1.1661267801235635 1.0347632156678646 0.9084751371072322 1.037224015803832 1.0 13.446641492961726 -4.75365778785245 23.834020675884606 0.997422276473684 1.0868710914742252 0.0457635239201607 0.12150053930928406 565.8133659347664 1732750.9071908034 0.028586889262181885 0.2906844127285427 1.763364982389588e-05 4.75365778785245 0.08944881500054125 S(ph)DSQASLTVPLSPQVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDSQASLTVPLSPQVVR 17 0 Q8TEV9-2;Q8TEV9 Q8TEV9-2 SMCR8 Smith-Magenis syndrome chromosomal region candidate gene 8 protein 1 S(0.97)DS(0.029)QAS(0.001)LTVPLSPQVVR 123.42 4.4875e-05 2719500.0 14391.0 14748.0 13564.0 13142.0 14238.0 11550.0 12783.0 11929.0 10598.0 7960.7 True False 16827.112064793862 16212.083973863515 13887.417201756449 12405.696346938874 11448.166108338195 10944.297667387045 11572.101699094439 11615.87638982027 10752.97570055382 9403.911893133476 1.7893736410993641 1.7239723381182688 1.4767702377025382 1.3192059313100575 1.2173833866624577 1.1638026591229895 1.230562539356002 1.2352174841516668 1.143457725120266 1.0 13.199045306858586 -5.46223757173987 1.0336706970071723 1.1681290782173686 1.8702231751353848 0.9352379949865731 0.0618542216566586 0.1745457374166787 0.2974702407454676 0.02155481468445681 0.10624375813359431 3.449549872817689e-06 5.46223757173987 0.7020940969180163 S(ph)DSRAQAVSEDAGGNEGR ddPTM_PC-9_AZD4547_30min_R2 1 SDSRAQAVSEDAGGNEGR 18 1 P55884;P55884-2;C9JZG1 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 1 S(0.534)DS(0.465)RAQAVSEDAGGNEGR 47.68 0.041519 17512000.0 6850.3 7846.5 6807.3 11303.0 10111.0 9536.2 3910.9 8334.7 3377.5 10436.0 True False 9028.552904908409 10382.727678329495 6717.030754189191 8697.267979609202 8707.26217856416 8939.899906489112 4258.962523582799 7046.763627352478 3556.02775469709 10070.638816471177 0.8965223626272477 1.0309899766584694 0.6669915262180841 0.8636262443832521 0.864618654014567 0.8877192469525698 0.4229088741239525 0.6997335279095744 0.3531084591059882 1.0 13.297867581079217 -7.2396260333059335 24.5722785102229 0.593915505640862 0.8662559555473354 0.3069328307059309 0.1820888058978648 699.1178233092112 787542.4911519059 0.06525981721394218 0.05050232123567682 5.759356563892649e-08 7.2396260333059335 0.2723404499064733 S(ph)DSVSASER ddPTM_PC-9_AZD4547_30min_R2 1 SDSVSASER 9 0 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 S(0.509)DS(0.484)VS(0.006)ASER 144.77 0.00053041 141300000.0 100790.0 112560.0 111730.0 178420.0 151230.0 120230.0 146240.0 181540.0 148700.0 145430.0 True False 132839.12343776444 148942.81876923068 110248.38719691487 137288.025561521 130234.32491981567 112711.9990936837 159255.07669558146 153487.16437419062 156559.97842293343 140338.53996544678 0.9465619598897865 1.0613108758713208 0.7855888141921634 0.9782631741453428 0.9280011389022652 0.8031435920698256 1.1347921728043642 1.0936921847126329 1.1155879095042645 1.0 17.09855173272932 -7.278056567752049 24.996435992905234 1.0938257590490184 0.9209896631183443 0.5046730339190131 0.08176162412041303 688.6101802091212 1035839.0822312635 0.03371818228840494 0.0228048255996639 5.271611931180926e-08 7.278056567752049 -0.17283609593067406 S(ph)DSVSASER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDSVSASER 9 0 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 S(0.523)DS(0.476)VS(0.001)ASER 153.1 6.6791e-05 85490000.0 69203.0 71156.0 68824.0 78580.0 73076.0 68530.0 91901.0 91771.0 70529.0 59837.0 True False 80917.70107844686 78219.89742637868 70465.02517647347 74177.41735979746 58757.2823804553 64936.16615982979 83195.47197437818 89362.10848941216 71560.3531972411 70684.97443056853 1.1447652309463532 1.1065986520687143 0.9968883167056797 1.0494085618246836 0.8312556219167992 0.9186700098988421 1.1769894895569113 1.2642306120827638 1.0123842269693741 1.0 16.109115952174996 -8.500546667925446 24.905716666856737 0.9999996354685813 1.056963895031284 0.032619788327047816 0.1188586977984324 3109.934249218571 3468338.0455284906 0.1274403094307611 0.032904946439603976 3.158299649195309e-09 8.500546667925446 0.05696425956270279 S(ph)DSVSASER ddPTM_PC-9_Lapatinib_30min_R1 1 SDSVSASER 9 0 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 S(0.732)DS(0.267)VS(0.001)ASER 176.6 0.0048186999999999995 101900000.0 53068.0 57646.0 53264.0 60597.0 79370.0 71382.0 84142.0 70249.0 95534.0 70766.0 True False 52311.24058852071 57512.524228759656 48884.83952498584 65053.50552566616 74701.61264742381 68329.15825956927 88498.46105003214 73513.02499658278 84773.95490238123 82997.80881023209 0.6302725498226852 0.6929402721975164 0.5889895194312557 0.7837978671750943 0.9000431905163078 0.8232646046812931 1.066274668194878 0.8857224793086343 1.021399915462951 1.0 16.34078562853503 -6.272889924741057 1.0183026426216304 0.9786300423280077 0.6272982670414304 0.816949107080613 0.06730277022626303 0.2145084648749607 0.4686829086017967 0.029623149802298864 0.045260449032613434 5.334700904294528e-07 6.272889924741057 -0.3513317752865772 S(ph)DSYVELSQYR ddPTM_PC-9_AZD4547_30min_R2 1 SDSYVELSQYR 11 0 P52298-3;P52298;F8WE41 P52298-3 NCBP2 Nuclear cap-binding protein subunit 2 1 S(0.94)DS(0.058)YVELS(0.002)QYR 155.88 0.00069335 4980300.0 12051.0 10154.0 13354.0 13953.0 16231.0 16466.0 15758.0 23826.0 22123.0 13980.0 True False 15882.96732362835 13436.0819277076 13176.917234651408 10736.351421701072 13977.605817453757 15436.378417005688 17160.43147270904 20144.239167012624 23292.37661500037 13490.564455180833 1.1773389746882499 0.9959614345527026 0.9767506228837612 0.7958415274149593 1.036102370949044 1.1442351777265773 1.2720321325116128 1.4932095120213116 1.7265679795966808 1.0 13.719663092524565 -7.248030000554968 1.794982405074692 1.4486396312981742 0.9862541338925258 0.4638171514460455 0.19082630888733626 0.2877489705269376 1.8103870008186518 0.09911899845837151 0.06223703503617504 5.648979509745676e-08 7.248030000554968 -0.4623854974056484 S(ph)DSYVELSQYR ddPTM_PC-9_Lapatinib_30min_R1 1 SDSYVELSQYR 11 0 P52298-3;P52298;F8WE41 P52298-3 NCBP2 Nuclear cap-binding protein subunit 2 1 S(0.638)DS(0.361)YVELSQYR 100.02 0.00432 4356800.0 6851.1 9944.7 7256.8 6972.0 11963.0 10800.0 11703.0 10110.0 9167.0 10743.0 True False 6753.402057662135 9921.673658150554 6660.173916058075 7484.7441379102 11259.359860162933 10338.109176029644 12308.924076781223 10579.747508369555 8134.515927210506 12599.913235852306 0.5359879811271819 0.7874398396585002 0.528588871319125 0.5940314030586182 0.8936061423125591 0.8204905051737315 0.976905463265962 0.8396682826565434 0.6456009477957533 1.0 13.621126178779674 -6.2598191953628755 24.996071307987766 0.8582939179733843 0.618155205065396 0.5445400509552769 0.11243816603038626 119.10021473288074 1837467.361131289 0.03355822579753975 0.04106296708232315 5.497697052793435e-07 6.2598191953628755 -0.24013871290798827 S(ph)DVPLR ddPTM_PC-9_AZD4547_30min_R2 1 SDVPLR 6 0 Q96RD9-4;Q96RD9-3;Q96RD9 Q96RD9-4 FCRL5 Fc receptor-like protein 5 1 S(1)DVPLR 104.75 0.03475 33803000.0 48756.0 53848.0 63665.0 90351.0 73761.0 59944.0 56437.0 78650.0 60794.0 51980.0 True False 64259.39381220015 71253.31294496737 62820.76050202798 69521.97285903487 63520.558357538444 56195.69220387403 61459.78366704404 66496.4496972022 64007.44672658912 50160.19602148066 1.281083387008329 1.4205150417365549 1.2524026117267473 1.3859988272227384 1.266353870115187 1.1203244138003114 1.2252700057377055 1.3256816155328757 1.2760605381043268 1.0 15.614255365621329 -6.519660138132004 24.752449107118576 1.209979972500423 1.3340793817073693 0.3343776173664924 0.09474356277898714 155.01968877214838 1192178.9503690994 0.03028825371092121 0.030887564116248697 3.0223159414032555e-07 6.519660138132004 0.12409940920694629 S(ph)DYDGIGSR ddPTM_PC-9_AZD4547_30min_R2 1 SDYDGIGSR 9 0 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDH3;A0A2R8YF89;A0A2R8YCU0;A0A2R8Y650 A0A2R8Y5G6 DDX3X ATP-dependent RNA helicase DDX3X 1 S(0.942)DY(0.058)DGIGSR 77.318 0.023234 2847300.0 13452.0 11678.0 18448.0 25435.0 20746.0 18252.0 16745.0 20965.0 16781.0 15258.0 True False 17729.45618101806 15452.685124263282 18203.367466290925 19571.35371683269 17865.77600202672 17110.699554669503 18235.272560636684 17725.340977773012 17668.00940090951 14723.822064173759 1.2041340966865974 1.0495023002120492 1.2363207995146621 1.3292305239448678 1.213392550124469 1.1621099114137987 1.2384877025244039 1.2038546038193845 1.1999608066372653 1.0 13.845864599673028 -9.049318592037485 3.0714869173547363 1.0000000874649582 1.204569950607916 0.4623356499907427 0.06605022497326592 25.526869909466207 147.4933479531422 0.06794168554682502 0.018021863360491306 8.926504082894535e-10 9.049318592037485 0.20456986314295778 S(ph)EAEDEDDEDYVPYVPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEAEDEDDEDYVPYVPLR 18 0 D6RD33;D6RGI7;A0A499FJW5;Q9UJV9 D6RD33 DDX41 Probable ATP-dependent RNA helicase DDX41 1 S(1)EAEDEDDEDYVPYVPLR 122.63 5.5746000000000005e-05 2508400.0 940.15 1490.3 6045.7 3466.2 5139.2 6447.3 3672.7 1830.6 4962.9 722.86 True False 1099.298826191088 1638.2471349504192 6189.852416444932 3272.000051572023 4132.210652055884 6109.192238177015 3324.7952679546365 1782.5486896810278 5035.473023615636 853.9087958433885 1.2873726462851722 1.9185270639264882 7.248844896053963 3.831791015034966 4.839170965529852 7.1543849506118375 3.8936187144796928 2.087516486957416 5.896968210337031 1.0 9.737938176703537 -5.064197695206241 11.700533661377571 4.595382963829719 1.4444525132416102 0.27411020528204744 1.8883689663145027 1.0759608254702497 194.9077807407085 0.46519978201768225 1.2339274669558373 8.625858006701608e-06 5.064197695206241 -3.150930450588109 S(ph)EAEDEDDEDYVPYVPLR ddPTM_PC-9_Lapatinib_30min_R1 6 SEAEDEDDEDYVPYVPLR 18 0 D6RD33;D6RGI7;A0A499FJW5;Q9UJV9 D6RD33 DDX41 Probable ATP-dependent RNA helicase DDX41 1 S(1)EAEDEDDEDYVPYVPLR;S(1)EAEDEDDEDYVPYVPLR;S(1)EAEDEDDEDYVPYVPLR;S(1)EAEDEDDEDYVPYVPLR;S(1)EAEDEDDEDYVPYVPLR;S(1)EAEDEDDEDYVPYVPLR 160.93 3.2262e-08 5240200.0 9551.3 4127.2 30341.5 7087.61 13140.44 18974.489999999998 8146.139999999999 10278.99 24095.4 4344.4800000000005 True False 9415.096710506099 4117.643721974415 27846.938991577026 7608.856482973854 12367.545154299029 18162.995294396555 8567.907269830854 10756.589400697883 21381.5223161894 5095.41757934428 1.847757630046429 0.8081072174862471 5.465094579188659 1.4932743714310113 2.42718971737162 3.564574445875723 1.6814926620662642 2.1110319680771146 4.196225723062515 1.0 12.314984667552283 S(ph)EDDSAVPLAK ddPTM_PC-9_AZD4547_30min_R2 2 SEDDSAVPLAK 11 0 Q9Y2W2 Q9Y2W2 WBP11 WW domain-binding protein 11 1 S(0.988)EDDS(0.012)AVPLAK;S(0.994)EDDS(0.006)AVPLAK 113.61 0.001542 7463100.0 47742.0 61184.0 53919.0 50154.0 51444.0 74748.0 59288.0 66766.0 59552.0 43080.0 True False 62922.962904710395 80960.53148166847 53203.99882995128 38591.77017157568 44301.888588077796 70073.99574361366 64564.517143925244 56448.84883004969 62699.79714218239 41571.78231253145 1.5135979119601715 1.947487622085032 1.279810387487606 0.928316469124359 1.0656721007298111 1.685614420300918 1.5530851349729797 1.3578645343053688 1.5082297090563297 1.0 15.343316981693334 -11.715726473047189 1.9446249256966868 4.8090963216421536e-05 1.4216731618348635 0.17453773561989105 0.278153096454936 6532897.753851272 1186134.2288372861 28724740.251446046 0.0774100683029248 1.924303310279936e-12 11.715726473047189 1.4216250708716471 S(ph)EDDSAVPLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SEDDSAVPLAK 11 0 Q9Y2W2 Q9Y2W2 WBP11 WW domain-binding protein 11 1 S(0.999)EDDS(0.001)AVPLAK;S(0.997)EDDS(0.003)AVPLAK 107.97 0.0043205 0.0 18615.2 24465.4 26718.0 24111.0 34195.0 34991.0 31391.0 26091.0 31195.0 23816.0 True False 21766.385693040847 26894.163225804205 27355.058448579268 22760.13883891668 27494.73522086141 33156.01036186495 28417.417228840917 25406.1388956996 31651.167859858102 28133.652272647734 0.7736779242914967 0.9559428319213076 0.9723251778147043 0.8090005029686343 0.977289935711351 1.178517813490575 1.010086317746561 0.9030515714591422 1.1250287574866413 1.0 14.780009233076834 -6.517205673602046 24.978504025885133 1.0399443908823378 0.8904623490335223 0.4330357364565396 0.08884396231581286 268.5472118928754 1182418.1141011338 0.02904668269327292 0.02992840359576772 3.039445261345281e-07 6.517205673602046 -0.14948204184881553 S(ph)EDLDNATEVNPK ddPTM_PC-9_AZD4547_30min_R2 2 SEDLDNATEVNPK 13 0 O95171-2;O95171;O95171-3 O95171-2 SCEL Sciellin 1 S(1)EDLDNATEVNPK;S(0.795)EDLDNAT(0.205)EVNPK 217.39 1.5308e-14 10886500.0 27269.0 34667.0 31328.0 29789.0 37633.0 44895.0 42492.0 45819.0 46933.0 34946.0 True False 35939.97476956447 45872.429799866 30912.570250648434 22921.606285462116 32408.3075428647 42087.708552864715 46273.70568208862 38738.726365875584 49413.78256438147 33722.55117673456 1.0657549181616996 1.3602894264866214 0.9166735366087975 0.6797115130861127 0.9610277518156287 1.2480582602511205 1.372188759965859 1.1487483898490374 1.4653038053204115 1.0 15.041426062650284 -6.770934484332958 17.113221327350598 1.2639945946348399 0.99483536330669 0.2893614572324993 0.19509015959806372 5.819216493762755 10484.601163961004 0.07212969177919984 0.06510432605356802 1.694593419731339e-07 6.770934484332958 -0.2691592313281499 S(ph)EDLDNATEVNPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEDLDNATEVNPK 13 0 O95171-2;O95171;O95171-3 O95171-2 SCEL Sciellin 1 S(1)EDLDNATEVNPK 73.02199999999999 0.022241 3640300.0 8295.0 9116.9 10313.0 10842.0 8542.9 8986.4 11625.0 8531.0 6640.9 8617.8 True False 9699.179666282056 10021.96558050693 10558.901032270296 10234.557890238259 6868.980070720773 8515.137364346927 10523.79584228841 8307.070289341666 6738.010599151521 10180.13892153273 0.9527551383180671 0.9844625557426101 1.037205986446454 1.0053456017766538 0.6747432548480953 0.83644608683443 1.0337575865520643 0.8160075568095436 0.6618780599250448 1.0 13.313469628589662 -6.188208747795868 24.997207839682364 0.8377343358306106 0.9972130015165076 0.320732472127097 0.11248342112949337 179.48279503130345 61265.500926104054 0.03398423085561034 0.043873463816185086 6.483227361210628e-07 6.188208747795868 0.15947866568589697 S(ph)EDLDNATEVNPK ddPTM_PC-9_Lapatinib_30min_R1 3 SEDLDNATEVNPK 13 0 O95171-2;O95171;O95171-3 O95171-2 SCEL Sciellin 1 S(1)EDLDNATEVNPK;S(1)EDLDNATEVNPK;S(1)EDLDNATEVNPK 231.13 4.0486e-20 8274400.0 52595.0 47312.0 41038.3 42329.1 48690.0 59639.0 56977.0 60790.0 61009.0 67658.0 True False 51844.985655258264 47202.45197084063 37664.28938641911 45442.12321973819 45826.1499282231 57088.37899529925 59926.99026939792 63614.5253248057 54137.52396674879 79352.59515138203 0.6533495918608947 0.5948444645167794 0.4746447084001024 0.5726608327433732 0.5775003305285722 0.7194267419533157 0.7551988710019424 0.8016691225214172 0.682240119097175 1.0 16.27598978535479 -8.309469667536689 0.3531222438828361 1.0182399107825915 0.5370089008568165 0.7577948655941539 0.06898415979689398 0.7073731559815244 0.2697181854693484 0.12576924366543987 0.08258167564487699 4.903772710537994e-09 8.309469667536689 -0.48123100992577494 S(ph)EEHS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEEHSPPR 8 0 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 2 S(1)EEHS(1)PPR 72.434 0.018047999999999998 0.0 2698.3 7697.1 4381.2 6489.5 6710.1 6267.4 7196.1 5172.2 6472.2 5283.5 True False 3155.0688961457367 8461.217219638243 4485.664423793524 6125.914354242866 5395.304073855888 5938.726510872866 6514.433312747671 5036.4352303988935 6566.843680800571 6241.356725837015 0.505510105372581 1.3556695429075203 0.7187002154875167 0.9815036414893161 0.8644441122106085 0.9515121105461948 1.0437527606426045 0.8069455811666442 1.052150032318479 1.0 12.607643956198523 -4.713820219382567 24.645586264044432 0.9590903505172067 0.5055012026520838 0.4250514630294894 0.16285872981843494 12950.893934786214 6702124.759809022 0.03720090079437105 32.871999734465625 1.9327682405061186e-05 4.713820219382567 -0.45358914786512294 S(ph)EESPVYSNSSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SEESPVYSNSSVR 13 0 H0Y8J2;Q03188 H0Y8J2 CENPC Centromere protein C 1 S(0.741)EES(0.258)PVYSNSSVR;S(0.684)EES(0.316)PVYSNSSVR 173.33 0.00019459 16586100.0 43210.0 39248.0 44469.0 41941.0 49962.0 42159.0 45104.0 43443.0 40877.0 32817.0 True False 50524.59956359828 43144.28205900426 45529.30960962163 39591.181744556634 40172.30475521794 39948.107823322134 40831.4225953184 42302.6672816633 41474.74879331367 38766.462320770916 1.3033069446867585 1.1129280175737812 1.1744509786034103 1.021274043965158 1.0362643984074291 1.0304811280630604 1.0532666679115852 1.0912181496374949 1.0698615842253851 1.0 15.24252146580828 -1.52287932717761 0.7200003446118312 1.047777397439771 36.97370880873763 0.7792329972285752 0.04046306430199209 146.49079968923323 0.7172212827396434 0.01560975462452436 8499.689139387769 0.029999959803987373 1.52287932717761 35.92593141129786 S(ph)EESPVYSNSSVR ddPTM_PC-9_Lapatinib_30min_R1 1 SEESPVYSNSSVR 13 0 H0Y8J2;Q03188 H0Y8J2 CENPC Centromere protein C 1 S(0.983)EES(0.017)PVYSNSSVR 203.85 1.0282999999999999e-09 13967000.0 52538.0 45687.0 56278.0 58020.0 55707.0 62970.0 51338.0 49037.0 66204.0 32904.0 True False 51788.79848571078 45581.21455850091 51651.04007936227 62286.98434904613 52430.42378417589 60276.91989023948 53996.0304412368 51315.438038369706 58747.408360973546 38591.41255817595 1.341977270400247 1.1811232483337568 1.3384076056169008 1.614011517592145 1.358603386313933 1.561925721152937 1.3991721697110369 1.3297113175376125 1.522292252775478 1.0 15.235992231238376 -10.649833322365135 3.8021243640054467 0.9998183995478495 1.403665542111917 0.49883053389603016 0.12184955492285938 18041379.830944236 32810015.85222628 43050.553372202674 0.03291330749908364 2.2395805009911155e-11 10.649833322365135 0.4038471425640676 S(ph)EGFSMDR ddPTM_PC-9_AZD4547_30min_R2 1 SEGFSMDR 8 0 Q7Z4V5-2;Q7Z4V5;Q7Z4V5-4;Q7Z4V5-3;K7ERA4 Q7Z4V5-2 HDGFRP2 Hepatoma-derived growth factor-related protein 2 1 S(1)EGFSMDR 93.649 0.006222600000000001 13187000.0 45704.0 35495.0 74497.0 84782.0 91816.0 78643.0 61270.0 90762.0 63816.0 67276.0 True False 60236.92129774375 46968.06460744353 73509.12110452485 65236.81976884247 79068.93325952403 73725.44077788036 66722.91130428253 76736.81840327353 67189.1834770538 64920.687717220666 0.9278540233603454 0.7234683774766132 1.132291164639435 1.0048695117494566 1.2179312333216463 1.1356232253578573 1.027760389645161 1.1820087109600743 1.0349425713066098 1.0 15.986390662259867 -5.270415308987352 24.955091583087338 1.0990883464109964 0.8256611977447842 0.6101372759791295 0.08498320741097076 327.8023184551489 911365.4089556516 0.020871619269276716 0.044487571782623865 5.365184867778367e-06 5.270415308987352 -0.2734271486662122 S(ph)EGFSMDR ddPTM_PC-9_Lapatinib_30min_R1 2 SEGFSMDR 8 0 Q7Z4V5-2;Q7Z4V5;Q7Z4V5-4;Q7Z4V5-3;K7ERA4 Q7Z4V5-2 HDGFRP2 Hepatoma-derived growth factor-related protein 2 1 S(1)EGFSMDR;S(0.999)EGFS(0.001)MDR 106.88 0.003819 10210200.0 10197.4 9249.9 17642.4 11878.8 24547.4 20244.4 23778.6 20331.2 25179.0 20897.7 True False 10051.983206025872 9228.482424862164 16191.909973633406 12752.406578515154 23103.570194045256 19378.594204001332 25009.73955841662 21275.86177469467 22343.075873375514 24509.839600565083 0.4101203177924559 0.3765215348308276 0.6606289652446398 0.5202974310048583 0.9426242917359849 0.790645492578195 1.0203958885899853 0.8680538967788327 0.911596168620393 1.0 14.581073422374091 -5.931316205467182 0.8675322439301708 0.9437436759572514 0.36113525846378136 0.8356302083059959 0.09335134508614076 0.2588614585649472 0.38250797464257186 0.04036633877736794 0.1033476345766979 1.171342212454029e-06 5.931316205467182 -0.58260841749347 down S(ph)EGGGTGESSQGGTSK ddPTM_PC-9_AZD4547_30min_R2 3 SEGGGTGESSQGGTSK 16 0 F5H0R1;Q9H6E5 F5H0R1 TUT1 Speckle targeted PIP5K1A-regulated poly(A) polymerase 1 S(0.999)EGGGT(0.001)GESSQGGTSK;S(1)EGGGTGESSQGGTSK;S(1)EGGGTGESSQGGTSK 157.84 4.677e-05 6557600.0 39112.3 30395.7 32195.6 36738.9 29502.2 36535.1 30162.8 39182.0 39497.0 39258.0 True False 51549.19781362122 40220.515604689994 31768.665307768675 28269.31421534676 25406.32877504061 34250.5544214226 32847.230766913824 33127.322212788065 41584.730785276384 37883.589369205205 1.3607263374975895 1.0616870332087494 0.8385864654523146 0.7462153055202924 0.6706420695102585 0.9041000335956597 0.8670569846693214 0.8744504616480874 1.097697749281375 1.0 15.209285408344828 -4.881941824225769 2.402410337895689 0.859802796252747 1.4197509786630162 0.6330721918563691 0.1135735675416385 0.2823189174870453 2.4045536386881388 0.03153927565698176 0.3054177606627411 1.3123756860978173e-05 4.881941824225769 0.5599481824102692 S(ph)EGGGTGESSQGGTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEGGGTGESSQGGTSK 16 0 F5H0R1;Q9H6E5 F5H0R1 TUT1 Speckle targeted PIP5K1A-regulated poly(A) polymerase 1 S(1)EGGGTGESSQGGTSK 181.81 2.3206999999999998e-29 0.0 5132.5 6300.7 9744.4 7760.1 16287.0 9440.6 11300.0 9448.9 15862.0 8345.7 True False 6001.330878504237 6926.191856124349 9976.743451842785 7325.326755583651 13095.679267207764 8945.51831677352 10229.582195084657 9200.8763869371 16093.951742044226 9858.70934547515 0.6087339293818077 0.7025454969217915 1.0119725718886123 0.7430310093223059 1.328336074053982 0.9073721522056274 1.0376188034978155 0.9332739270947291 1.632460312812738 1.0 13.267183072973127 -4.42952898694177 0.4304617603774912 1.1654040540306498 1.2876670964776229e-17 0.40277649933398596 0.22252237846245676 7.36587002536169 0.8494108746429955 0.15933434243612432 4.677957369833546 3.719383953424589e-05 4.42952898694177 -1.1654040540306498 S(ph)EGGGTGESSQGGTSK ddPTM_PC-9_Lapatinib_30min_R1 2 SEGGGTGESSQGGTSK 16 0 F5H0R1;Q9H6E5 F5H0R1 TUT1 Speckle targeted PIP5K1A-regulated poly(A) polymerase 1 S(1)EGGGTGESSQGGTSK;S(1)EGGGTGESSQGGTSK 232.62 2.3318999999999998e-30 5804000.0 6320.5 11358.8 13059.7 8798.8 15507.7 17111.4 24192.3 23849.0 26250.0 15165.900000000001 True False 6230.368510962256 11332.499396482592 11985.981877899858 9445.893103936349 14595.567575311265 16379.585310621624 25444.85892016697 24957.11160505495 23293.448575245555 17787.305607708513 0.35027050461550463 0.6371116371650695 0.6738503369900765 0.5310468776025733 0.8205609043443859 0.9208581486070142 1.43050664790624 1.4030855575022698 1.3095546390764679 1.0 14.11856036959271 -6.853521695238391 1.6819329303993387 1.3189991684870779 0.5673281368365436 0.821763332154106 0.15086722116127435 0.13853139270407092 0.8077832640714757 0.06545435308372863 0.05551248740446118 1.4011295895773987e-07 6.853521695238391 -0.7516710316505343 S(ph)EGSEYEEIPK ddPTM_PC-9_AZD4547_30min_R2 1 SEGSEYEEIPK 11 0 P48634 P48634 PRRC2A Protein PRRC2A 1 S(1)EGSEYEEIPK 149.41 0.0003088 7886100.0 29307.0 44824.0 40093.0 31029.0 25050.0 33062.0 38360.0 41864.0 40479.0 30304.0 True False 38626.01637653108 59312.4814189054 39561.34062369917 23875.743443271145 21572.239894474562 30994.62791346059 41773.96568683326 35394.8807390169 42618.637300483635 29243.066183819723 1.3208606831353058 2.0282579482627296 1.3528451625085942 0.8164582774319906 0.7376873464250663 1.059896651008847 1.4285084000509811 1.210368314886248 1.457392909231408 1.0 14.83580696773015 -5.518006055725239 24.44073137039875 1.1052576436604804 1.678557451309003 0.42101774409000225 0.2685936994921998 141.07663963322204 707618.9220082641 0.0762174725170063 0.13692151985709436 3.0338488804485572e-06 5.518006055725239 0.5732998076485225 S(ph)EGSEYEEIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEGSEYEEIPK 11 0 P48634 P48634 PRRC2A Protein PRRC2A 1 S(0.876)EGS(0.124)EYEEIPK 136.01 7.726e-05 10497000.0 23220.0 29825.0 25607.0 24075.0 23449.0 17070.0 26972.0 17564.0 20622.0 18468.0 True False 27150.687384095174 32785.82889344178 26217.567995088295 22726.15580220311 18854.336780054953 16174.81914998243 24417.01689963036 17102.96361059629 20923.557737008952 21816.102207392425 1.2445251276323372 1.502827066987807 1.2017530787972026 1.0417147658256896 0.8642394778323933 0.741416546192269 1.1192199535697356 0.7839605557403797 0.9590878122086799 1.0 14.413105743888163 -5.735096239290152 2.194988948135599 0.9051548078913803 1.3728565162281436 0.7047664265876605 0.11927628458765943 0.1514354501619964 1.4863789774125502 0.03423497687849271 0.06687276774712844 1.840364133142441e-06 5.735096239290152 0.4677017083367634 S(ph)EGSEYEEIPKR ddPTM_PC-9_AZD4547_30min_R2 1 SEGSEYEEIPKR 12 1 P48634 P48634 PRRC2A Protein PRRC2A 1 S(0.986)EGS(0.009)EY(0.004)EEIPKR 59.225 0.029798 4732100.0 11735.0 16087.0 24898.0 18875.0 19835.0 23497.0 19185.0 26141.0 23249.0 18362.0 True False 15466.485896836666 21286.808151569054 24567.836251935798 14523.660365843014 17081.252627022066 22027.728875524277 20892.427833730348 22101.509110420408 24477.894676225787 17719.151968957824 0.8728682909843766 1.2013446348257188 1.386513095828524 0.8196588861186478 0.9639994429161569 1.243159317901593 1.1790873440406056 1.247323187313932 1.3814371432170458 1.0 14.113021938326382 -6.7804780955451776 24.967127038431347 1.2237145175277346 1.0633705295233895 0.17055542064567875 0.17517726774438677 470.32328912761216 616771.6997960425 0.06385422023815399 0.05640276394831642 1.657760947015618e-07 6.7804780955451776 -0.16034398800434513 S(ph)EGSEYEEIPKR ddPTM_PC-9_Lapatinib_30min_R1 2 SEGSEYEEIPKR 12 1 P48634 P48634 PRRC2A Protein PRRC2A 1 S(1)EGSEYEEIPKR;S(1)EGSEYEEIPKR 109.6 0.00059275 11133000.0 63730.0 59505.0 41559.0 33704.0 55963.0 43430.0 50509.0 56920.0 50631.0 39942.0 True False 62821.19851334936 59367.219828476285 38142.17944237924 36182.704593248025 52671.36636749125 41572.600140274764 53124.10887756496 59564.71099667606 44928.40361193361 46845.921480630415 1.3410174573964633 1.2672868406062436 0.8142049134021208 0.7723768355844733 1.1243532991291356 0.887432647844572 1.1340178013048674 1.2715026007398433 0.9590675600331685 1.0 15.515635828377317 -5.106396998060023 6.482825658990496 1.0033233139279267 1.3231186920274849 0.4248901497644566 0.14447076699426137 0.2260185165756728 11.585037794208365 0.0398094658999493 0.10886798275527546 7.827138198637868e-06 5.106396998060023 0.31979537809955816 S(ph)EGSPVLPHEPAK ddPTM_PC-9_AZD4547_30min_R2 3 SEGSPVLPHEPAK 13 0 Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5;Q9UKE5-8;Q9UKE5-5;Q9UKE5-7;Q9UKE5-3 Q9UKE5-6 TNIK TRAF2 and NCK-interacting protein kinase 1 S(0.66)EGS(0.34)PVLPHEPAK;S(0.516)EGS(0.484)PVLPHEPAK;S(0.827)EGS(0.173)PVLPHEPAK 89.506 0.0034415 105462000.0 252969.0 287355.0 311261.0 379172.0 330016.0 348052.0 317293.0 372855.0 288353.0 301440.0 True False 333407.87991792767 380236.8842167049 307133.47576567554 291759.75354900275 284198.9748908156 326288.2534189036 345531.46232201206 315238.82710553554 303594.750895683 290886.6773511952 1.1461778963338205 1.3071650021208596 1.055852672808611 1.0030014306800084 0.9770092514333156 1.1217022944813906 1.187855921998252 1.0837169648884928 1.0436873687726338 1.0 18.15009769676191 -5.278367867565216 24.533779796887128 1.063991545844255 1.2266714454499663 0.4830255733000729 0.06919506447946888 505.62589298910706 732783.2536671486 0.019341745111661708 0.040434538208591525 5.267834623686067e-06 5.278367867565216 0.16267989960571128 S(ph)EGSPVLPHEPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SEGSPVLPHEPAK 13 0 Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5;Q9UKE5-8;Q9UKE5-5;Q9UKE5-7;Q9UKE5-3 Q9UKE5-6 TNIK TRAF2 and NCK-interacting protein kinase 1 S(0.5)EGS(0.5)PVLPHEPAK;S(0.604)EGS(0.396)PVLPHEPAK;S(0.559)EGS(0.441)PVLPHEPAK 92.38 0.0026333000000000003 43452900.0 188745.0 211954.0 211135.0 206361.0 218193.0 158146.0 164745.0 128828.0 130951.0 123292.0 True False 220695.80061632354 232995.3923648128 216169.25913394603 194799.26220138907 175439.64796155604 149852.54535987828 149139.16094948832 125446.40150454908 132865.91064004737 145643.86362106513 1.5153113569585592 1.5997611335759265 1.4842318362026787 1.3375040826176927 1.204579744039291 1.0288970756074094 1.0239989330241692 0.8613229447890395 0.9122657648367299 1.0 17.1520853924619 -6.33302972729938 0.9219019845585925 0.9205097186748896 1.5809659299025542 0.965278760649221 0.047746808339136436 0.09207053119015476 0.16832185915445824 0.02372696389698222 0.03511017463520868 4.6448348040923927e-07 6.33302972729938 0.6604562112276646 S(ph)EGSPVLPHEPAK ddPTM_PC-9_Lapatinib_30min_R1 3 SEGSPVLPHEPAK 13 0 Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5;Q9UKE5-8;Q9UKE5-5;Q9UKE5-7;Q9UKE5-3 Q9UKE5-6 TNIK TRAF2 and NCK-interacting protein kinase 1 S(0.659)EGS(0.341)PVLPHEPAK;S(0.561)EGS(0.439)PVLPHEPAK;S(0.676)EGS(0.324)PVLPHEPAK 107.61 0.0005605 201103000.0 1331790.0 1235070.0 1126720.0 965810.0 984440.0 803540.0 707440.0 725370.0 757640.0 550250.0 True False 1312798.430379624 1232210.2712974746 1034085.4308649768 1036838.8892477143 926537.1746835076 769174.4673432285 744067.7816694962 759073.3382933752 672306.6048971068 645359.9793379611 2.0342110952190606 1.9093379055849273 1.6023389487612598 1.6066054952948117 1.4356904740730756 1.1918533717140034 1.1529499899153863 1.1762014419798177 1.041754410595446 1.0 19.299744589291635 -5.313579112843661 0.38947138062709924 0.9894770902724117 2.548707463622853 0.9758197953082067 0.05357541040147263 0.5566884246206967 0.09103845900754333 0.05060658366915815 0.39076927389918065 4.857590350420286e-06 5.313579112843661 1.5592303733504411 up S(ph)EHSLFQAK ddPTM_PC-9_Lapatinib_30min_R1 1 SEHSLFQAK 9 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6 Q8NEY1-2 NAV1 Neuron navigator 1 1 S(0.975)EHS(0.025)LFQAK 113.44 0.00045801 0.0 24685.0 27035.0 21480.0 21552.0 29213.0 20800.0 19223.0 24001.0 26859.0 19074.0 True False 24332.987373325403 26972.40211852546 19713.997315197794 23137.00597536439 27494.748774967786 19910.43248716819 20218.272881138633 25116.174079958233 23833.856582191238 22370.915485492587 1.0877063743370363 1.2056905823106305 0.8812333732154238 1.0342449324601226 1.2290399466574344 0.8900142017022054 0.903774943598087 1.1227155230301562 1.0653947800056445 1.0 14.449336676597126 -6.780720216789838 24.999956665221415 0.9982618690813639 1.0797175669092731 0.14536282485006413 0.10969863016709598 600.2112954091584 778242.1662128858 0.04080178762785227 0.0360368989611266 1.6568369949601403e-07 6.780720216789838 0.08145569782790918 S(ph)EIVGVSR ddPTM_PC-9_AZD4547_30min_R2 2 SEIVGVSR 8 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 S(1)EIVGVSR;S(1)EIVGVSR 135.55 0.0035207 72126000.0 8653.8 18204.4 38845.0 48273.0 48077.0 40377.0 29612.0 47547.0 29893.0 41071.0 True False 11405.528389778026 24088.616293555286 38329.889919127876 37144.40566041535 41402.33841942729 37852.21980708361 32247.410633954834 40199.703671365256 31473.082952230965 39633.11679103946 0.2877777301722753 0.6077901069592744 0.9671177293781188 0.9372062726293893 1.0446399822077033 0.9550654319380077 0.8136481116026071 1.0142957941792228 0.7941107210459569 1.0 15.274418806410319 -4.969204843074518 2.283036259524377 0.9423360469783988 0.24233774240110015 0.875923996609187 0.07863246624919928 0.1265798536932013 1.052826839808655 0.020774482226146987 0.15347642172137116 1.0734829646953159e-05 4.969204843074518 -0.6999983045772986 down S(ph)EIVGVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SEIVGVSR 8 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 S(1)EIVGVSR;S(1)EIVGVSR 131.12 0.0034688 56478000.0 33678.0 37339.0 48872.0 33480.0 40461.0 32255.0 28317.0 27560.0 30865.0 24234.0 True False 39379.02022917987 41045.76915514577 50037.293828092144 31604.224143624524 32532.95750171876 30563.491018317687 25634.60876267364 26836.579202233745 31316.34223415678 28627.432363761534 1.3755694093972743 1.4337914987829705 1.7478792087352062 1.1039838900687162 1.1364259668254808 1.067629490132232 0.8954560938941767 0.9374427598405658 1.093927734636762 1.0 14.80511065826304 -5.8868913649525885 6.37076237213788 1.0241294537144137 1.5081976483547297 0.798877891020076 0.11212108765977548 0.0942798941779518 4.908863726412708 0.033581044856359044 0.050283315368234216 1.297503789861824e-06 5.8868913649525885 0.48406819464031603 S(ph)EIVGVSR ddPTM_PC-9_Lapatinib_30min_R1 2 SEIVGVSR 8 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 S(1)EIVGVSR;S(1)EIVGVSR 134.84 0.0037234 71379000.0 35466.7 41898.0 52744.0 25317.8 27946.6 34208.0 28556.6 23253.8 47692.0 21456.8 True False 34960.93835420379 41800.98775520546 48407.591917727776 27179.755469704938 26302.835933129598 32745.00358274276 30035.121019483093 24334.256440170524 42320.42474097562 25165.579290611167 1.389236383175455 1.6610381693379366 1.9235635849554154 1.080036948716107 1.0451909582285166 1.3011821903483598 1.1935000848833497 0.9669658766507793 1.6816789413929614 1.0 14.619164187401068 -5.7739884838958995 24.991136575124937 1.1796876229559614 1.6582552869334903 0.4808406911837283 0.22699615585434146 179.40298339983445 357275.0796725037 0.062302363872514484 0.09312796679069915 1.6827186808098001e-06 5.7739884838958995 0.4785676639775289 S(ph)ELPQDVYTIK ddPTM_PC-9_AZD4547_30min_R2 2 SELPQDVYTIK 11 0 H0Y8C4;E9PFR3;Q14738-3;Q14738-2;Q14738 H0Y8C4 PPP2R5D Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform 1 S(1)ELPQDVYTIK;S(0.999)ELPQDVY(0.001)TIK 99.161 0.0046767 14292600.0 60248.0 54592.0 67257.0 69485.0 79562.0 66581.0 86990.0 90996.0 64676.0 79665.0 True False 79405.61076375065 72237.79639525447 66365.12823505694 53466.30678254849 68516.18964008734 62417.67954467731 94731.94147804011 76934.65908005866 68094.64132132918 76875.9525981387 1.0329057147276663 0.9396670083929922 0.8632755236474787 0.6954880554396279 0.8912564634905901 0.8119272338771455 1.2322701478997184 1.0007636520906198 0.8857729760733771 1.0 16.230244761963107 -7.2093170137234805 24.999962542260462 1.029766419798615 0.8678748409328922 0.31426958517286363 0.11369858225693673 426.3801334075396 204508.94654355245 0.045392245544045695 0.035160645844341976 6.175654430117525e-08 7.2093170137234805 -0.1618915788657227 S(ph)ELPQDVYTIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SELPQDVYTIK 11 0 H0Y8C4;E9PFR3;Q14738-3;Q14738-2;Q14738 H0Y8C4 PPP2R5D Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform 1 S(1)ELPQDVYTIK;S(1)ELPQDVYTIK 115.57 0.0013459000000000001 11365200.0 64608.0 82822.0 62973.0 57218.0 66705.0 41945.0 40310.0 46914.0 36320.0 33058.0 True False 75544.85833383384 91044.02080847045 64474.51514643246 54012.260963258865 53634.634095849164 39745.330360047585 36491.54498087275 45682.55720949179 36851.11128931069 39051.15371301597 1.9345102807719177 2.3314041238716325 1.6510271532628942 1.3831156272665068 1.3734455706483375 1.0177760854937363 0.9344549779257844 1.1698132543076578 0.9436625498986988 1.0 15.253077551001454 -5.762361093347252 1.0017033696696658 1.0221730045148554 2.2140399295696005 0.8857738003730757 0.15093752863897736 0.19187958048267406 0.36306637012636683 0.05815435068534176 0.1749224764644033 1.7283787043391533e-06 5.762361093347252 1.1918669250547451 S(ph)ELPQDVYTIK ddPTM_PC-9_Lapatinib_30min_R1 2 SELPQDVYTIK 11 0 H0Y8C4;E9PFR3;Q14738-3;Q14738-2;Q14738 H0Y8C4 PPP2R5D Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform 1 S(1)ELPQDVYTIK;S(1)ELPQDVYTIK 148.72 0.00029053 13626300.0 52491.0 115907.0 109748.0 102073.0 88148.0 85232.0 73173.0 75714.0 91130.0 84560.0 True False 51742.46871432951 115638.62446280457 100724.94307953106 109579.78892554641 82963.30794563577 81586.82604549614 76961.53990176134 79231.9488475464 80865.97975855721 99176.08333088229 0.5217232519830464 1.1659930557753335 1.015617270783736 1.1049013557024037 0.8365253512668406 0.822646179455354 0.7760090670751101 0.7989017733560213 0.8153778314552221 1.0 16.597704631008035 -6.4331725359430205 12.490641779388604 0.8262701838439083 0.9718633850226818 0.08259487623018547 0.17132284106704476 1.9587095096200637 268.1153251811902 0.051534880967471886 0.05842935863577978 3.688310407470793e-07 6.4331725359430205 0.1455932011787735 S(ph)ELSPVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SELSPVAR 8 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 S(0.607)ELS(0.393)PVAR 68.846 0.042481 13922000.0 24435.0 35198.0 37678.0 30646.0 42359.0 26555.0 29502.0 39015.0 33280.0 24401.0 True False 28571.36288675129 38692.22482452184 38576.38641461072 28929.003975672535 34059.05802662578 25162.40905259421 26707.356984016573 37990.897589809516 33766.65704042564 28824.708141790285 0.9912108301741417 1.3423284161002678 1.3383096968354862 1.0036182789213064 1.1815924677914327 0.8729458396879153 0.926543882166704 1.3179976498957164 1.1714483586208626 1.0 14.815018379810764 -5.768836528521344 24.99959002688498 1.0717299680352377 1.2357875306936796 0.17767373549260013 0.15320554671020545 286.77610697912326 969198.8046198139 0.04495820323193301 0.06821352771341835 1.7027993333533286e-06 5.768836528521344 0.16405756265844196 S(ph)ELVVEVK ddPTM_PC-9_AZD4547_30min_R2 1 SELVVEVK 8 0 P43121 P43121 MCAM Cell surface glycoprotein MUC18 1 S(1)ELVVEVK 72.434 0.032692 2742800.0 20940.0 30582.0 20637.0 21443.0 21513.0 20726.0 28598.0 26203.0 27104.0 18047.0 True False 27598.48442094246 40467.03343639489 20363.339896023732 16499.647641047522 18526.291291410427 19429.999943572202 31143.166598333097 22153.928435038677 28536.662106087315 17415.180023079276 1.5847372455735669 2.3236643768692833 1.1692867871039772 0.9474290601177562 1.0638013082183855 1.115693315706344 1.7882770408954118 1.2721044746984773 1.638608505239074 1.0 14.088057765885589 -5.2765589884376745 24.66780991870599 1.256175207920867 1.9542008212599704 0.46125345700116827 0.30461296085178596 524.367713261117 855511.8992895283 0.0814915666786192 0.17073552391215305 5.289821428556696e-06 5.2765589884376745 0.6980256133391034 S(ph)EPLPPSATAPPPPGPMQPR ddPTM_PC-9_AZD4547_30min_R2 1 SEPLPPSATAPPPPGPMQPR 20 0 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;Q8WUI4-10 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 S(1)EPLPPSATAPPPPGPMQPR 159.04 1.0464e-20 0.0 4959.1 5812.8 8290.5 5864.1 6883.3 6481.5 5196.0 10106.0 6157.8 5902.1 True False 6535.990644312122 7691.673924500563 8180.5625530835305 4512.222344441855 5927.672609406654 6076.210780385179 5658.433934014223 8544.349912777194 6483.288736602145 5695.469275459427 1.1475771930636731 1.350489933751791 1.43632809825379 0.7922476842925072 1.0407698334793487 1.0668498918195004 0.9934974029963113 1.5002012124958677 1.1383238892249432 1.0 12.475599001658852 -5.723592444725962 24.9999487997213 1.0915403442436182 1.3153674991703408 0.2614863846589679 0.1799908310782213 256.02021005653745 169113.40111124222 0.05153995438377983 0.08926724024398114 1.8897639297288776e-06 5.723592444725962 0.22382715492672256 S(ph)EPSLEPESFR ddPTM_PC-9_AZD4547_30min_R2 1 SEPSLEPESFR 11 0 Q9C0B5;Q9C0B5-2;H0YEF4 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5;Palmitoyltransferase 1 S(1)EPSLEPESFR 79.07 0.017688 2112400.0 3653.2 3962.5 2880.1 2705.2 2396.6 3194.9 4789.7 6075.8 3087.4 2526.6 True False 4814.84160871953 5243.300634089168 2841.9079921760886 2081.557934923365 2063.8734583272535 2995.1223979406946 5215.97402112162 5136.9247179944305 3250.593660947979 2438.1445030371874 1.9747974751790554 2.1505290714137772 1.165602772368879 0.8537467456626857 0.8464934936203716 1.228443348706232 2.1393211167853674 2.1068992061772316 1.3332243666848813 1.0 11.251567918264653 -7.229023242589165 24.646011884369706 1.7371030535265342 1.348873196719956 0.053010926275000814 0.5084317072292824 1357.1357620693539 1031832.2677252543 0.21270958284337144 0.16475117556076216 5.901694946124264e-08 7.229023242589165 -0.38822985680657807 S(ph)EPSLEPESFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SEPSLEPESFR 11 0 Q9C0B5;Q9C0B5-2;H0YEF4 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5;Palmitoyltransferase 1 S(0.946)EPS(0.054)LEPESFR;S(0.997)EPS(0.003)LEPESFR 103.08 0.0030519 3071800.0 24220.9 36152.4 34932.0 27429.1 42590.0 27388.7 28193.4 22383.4 23064.1 22156.6 True False 28321.019985419054 39741.371349111956 35764.91136034771 25892.33645334202 34244.79523487316 25952.388356949246 25522.71704946015 21795.859467172693 23401.368829509647 26173.41618845091 1.0820528654534514 1.5183868648620635 1.3664594297831505 0.9892608693842222 1.3083808008976594 0.9915552547703271 0.9751389297329142 0.8327479802499063 0.8940892033740542 1.0 14.675814618665415 -6.7039218121703525 0.9336323021665566 0.8904050306280179 1.3119435449499321 0.5246159882802913 0.1467564199044342 0.4177625585201214 0.7908151709393456 0.08545689207171203 0.08354659663247725 1.977325594164009e-07 6.7039218121703525 0.42153851432191425 S(ph)EPSLEPESFR ddPTM_PC-9_Lapatinib_30min_R1 2 SEPSLEPESFR 11 0 Q9C0B5;Q9C0B5-2;H0YEF4 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5;Palmitoyltransferase 1 S(1)EPSLEPESFR;S(1)EPSLEPESFR 175.74 0.00011923 6095900.0 29693.0 30302.0 11627.599999999999 8450.0 11702.7 5431.5 4237.1 7267.7 12137.5 3558.39 True False 29269.57237497068 30231.83758074933 10671.623611833978 9071.441188373663 11014.370194393437 5199.20740644491 4456.476305710477 7605.38387404327 10770.446936458771 4173.452970243366 7.013274759213087 7.243842879337976 2.5570250073314438 2.173605705647782 2.639150428416391 1.2457807584068041 1.0678151491067618 1.822324087097543 2.5807040388982068 1.0 12.027025798232108 -5.304091011521173 3.822656247081146 1.8403983651267137 7.230964245151116 0.9342193822927921 0.5587215918746576 0.04989386162816611 1.5481772534894764 0.15875924742319208 0.38983189936227436 4.964882655869657e-06 5.304091011521173 5.390565880024402 S(ph)EQKDPLEEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEQKDPLEEPK 11 1 Q9H9J4-2;Q9H9J4;C9JPC9 Q9H9J4-2 USP42 Ubiquitin carboxyl-terminal hydrolase 42 1 S(1)EQKDPLEEPK 55.173 0.040557 4190800.0 41272.0 49422.0 39203.0 38050.0 53365.0 34518.0 45956.0 39161.0 39308.0 26509.0 True False 48258.53444084305 54328.28954138071 40137.74819820543 35918.18185976443 42908.51133385785 32707.815314533866 41602.714987372594 38133.0652445093 39882.80513657005 31314.871854871457 1.541073987608727 1.7349037796854085 1.2817471642299394 1.1470007613707307 1.3702279074529518 1.0444818508636406 1.3285289871272687 1.217730202481323 1.2736058867303248 1.0 14.934560354780821 -5.351746419517166 5.050016378381237 1.2135230200156013 1.6360653894336354 0.6799457375238338 0.11855210154898449 0.10817312248680576 4.490836728829545 0.028859780098933304 0.06264680086124287 4.448909593127187e-06 5.351746419517166 0.42254236941803414 S(ph)ERS(ph)ERSERS(ph)HK ddPTM_PC-9_AZD4547_30min_R2 1 SERSERSERSHK 12 3 O15042-2;O15042;E7ET15;O15042-3 O15042-2 U2SURP U2 snRNP-associated SURP motif-containing protein 3 S(1)ERS(0.777)ERS(0.27)ERS(0.953)HK 73.415 0.02207 7925300.0 6826.9 9296.3 12919.0 17680.0 12820.0 12823.0 10043.0 16250.0 10333.0 13168.0 True False 8997.712191658651 12301.147175945265 12747.685618875359 13604.14915327706 11040.164289307937 12021.175782901977 10936.807544131043 13738.935887851716 10879.181284762404 12706.992328027265 0.7080914160790658 0.9680612735409586 1.0032024329438163 1.070603397097437 0.8688259191718501 0.9460284127493638 0.8606920710897258 1.0812106856748736 0.8561570672209082 1.0 13.633334972683391 -4.760656681726143 24.97375073396087 0.9623408497745124 0.7080911174348393 0.4926129121786136 0.0771945799007324 15.819141587150044 504423.7602572249 0.018561991006407298 0.1084733130154536 1.7351751455802562e-05 4.760656681726143 -0.2542497323396731 S(ph)ERSERS(ph)ERS(ph)HK ddPTM_PC-9_AZD4547_30min_R2 1 SERSERSERSHK 12 3 O15042-2;O15042;E7ET15;O15042-3 O15042-2 U2SURP U2 snRNP-associated SURP motif-containing protein 3 S(0.961)ERS(0.252)ERS(0.787)ERS(1)HK 63.727 0.045016 15175000.0 22182.0 22613.0 32278.0 48514.0 38636.0 37503.0 25308.0 33687.0 21448.0 32924.0 True False 29235.414585737624 29922.21002868349 31849.97262992948 37329.84683382826 33272.058305904946 35157.93148141411 27560.362971907638 28481.44820024991 22581.697493040167 31771.340781285646 0.9201819585454271 0.9417987813189378 1.0024749301323208 1.1749534617001987 1.047234944692774 1.1065926277220028 0.8674598645878234 0.8964509365946057 0.7107568310853762 1.0 14.95543835401054 -7.2815188194224945 21.54591114186805 0.8600376129863989 1.0339168884228767 0.41237911232415636 0.09540213436625032 141.70134176614104 152047.7338097431 0.041317022398211334 0.027930915670216095 5.2297530343407114e-08 7.2815188194224945 0.17387927543647774 S(ph)ESAPTLHPYSPLSPK ddPTM_PC-9_AZD4547_30min_R2 2 SESAPTLHPYSPLSPK 16 0 Q8WUF5;K7EN03 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 S(0.536)ES(0.421)APT(0.044)LHPYSPLSPK;S(0.357)ES(0.357)APT(0.285)LHPYSPLSPK 112.82 0.00017241 81042000.0 97362.0 125247.0 161480.0 200652.0 225624.0 211075.0 171608.0 235791.0 179679.0 188476.0 True False 128321.0907445941 165730.64341142352 159338.66969084225 154394.78144249704 194300.00215372944 197876.4468826357 186880.77955125397 199354.91888815077 189176.4651180512 181877.51260762996 0.7055357691273533 0.9112211896638338 0.8760768024939319 0.8488942873085016 1.068301404434197 1.0879654336900941 1.0275089914739362 1.0960943770889662 1.0401311432390627 1.0 17.472607653187787 -6.258875792007881 23.486078012880355 1.0585786533691435 0.843748695975988 0.7810028995208 0.056417703206648004 44.09223043614876 403944.65959584573 0.01645996200336296 0.02025038137480838 5.509652496442415e-07 6.258875792007881 -0.21482995739315547 S(ph)ESELIDELSEDFDRSECK ddPTM_PC-9_AZD4547_30min_R2 1 SESELIDELSEDFDRSECK 19 1 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;P20810-2;E9PCH5;P20810-3;H0Y7F0;H0Y9H6;E7EQ12;E7EQA0;H0YD33;A0A0A0MR45;D6RC54 P20810-6 CAST Calpastatin 1 S(0.978)ES(0.022)ELIDELSEDFDRSECK 71.001 0.0031256 3929600.0 6490.7 7611.9 9326.3 10866.0 11696.0 10634.0 7628.5 12701.0 7233.2 11937.0 True False 8554.607585053067 10072.297816182534 9202.627168303834 8361.011578026502 10072.212287655664 9969.054298945624 8307.421721637316 10738.352289944902 7615.532185129527 11519.089263340024 0.7426461753602742 0.8744005351393567 0.7989023227375773 0.7258396377425225 0.8743931102010725 0.8654377156944647 0.7211873726923905 0.9322223349826927 0.6611227685652434 1.0 13.491739036676659 -10.629300005894768 4.043200870058848 1.0000465163318082 0.8053187925683363 0.34719558397763695 0.08210901041429829 13492780.84428353 5072778.1890607895 5467.3025453734135 0.018314157027614915 2.3480102805851576e-11 10.629300005894768 -0.19472772376347192 S(ph)ESETSTMAAK ddPTM_PC-9_AZD4547_30min_R2 3 SESETSTMAAK 11 0 A0A087WVF1;Q96B23-2;Q96B23 A0A087WVF1 C18orf25 Uncharacterized protein C18orf25 1 S(0.987)ES(0.012)ETSTMAAK;S(0.848)ES(0.151)ETSTMAAK;S(0.941)ES(0.054)ET(0.002)S(0.002)T(0.002)MAAK 78.692 0.015946000000000002 27672900.0 93700.0 82109.0 107064.0 111734.0 109227.0 112238.0 107213.0 123244.0 102652.0 106531.0 True False 123494.65091892608 108649.12852099116 105644.26140562502 85975.45257309152 94062.7164452604 105219.7401170827 116754.74930089804 104199.47166537805 108077.97515178852 102801.38211551277 1.2012936828043939 1.0568839278727553 1.027654096001529 0.8363258431339494 0.9149946674799259 1.0235245670029276 1.1357313189593752 1.0135999100507649 1.0513280359435897 1.0 16.64950013544518 -4.779961009285526 2.2036085207752487 0.9982822546248913 1.2543174141963984 0.3956898542712467 0.07516891108756305 0.7602793659069946 4.278246694727229 0.022509984076531347 0.3891219417449421 1.6597359109059008e-05 4.779961009285526 0.25603515957150713 S(ph)ESETSTMAAK ddPTM_PC-9_Lapatinib_30min_R1 1 SESETSTMAAK 11 0 A0A087WVF1;Q96B23-2;Q96B23 A0A087WVF1 C18orf25 Uncharacterized protein C18orf25 1 S(0.992)ES(0.006)ET(0.001)S(0.001)T(0.001)MAAK 87.184 0.009256 6810900.0 21548.0 23674.0 22597.0 18269.0 28146.0 33003.0 31655.0 29839.0 34899.0 27808.0 True False 21240.721568580764 23619.184307526226 20739.161886942486 19612.56320359746 26490.507617165076 31591.538623750595 33293.94101089543 31225.42887262504 30968.30711723788 32614.575748169125 0.6512646901369903 0.7241910638329284 0.6358862996433953 0.6013435022130694 0.8122291033833904 0.9686325177945643 1.0208301119098397 0.9574071762800083 0.9495235307169783 1.0 14.993229241552394 -6.563514118322543 2.910962415815292 0.980228923247144 0.6579779559135164 0.9484915959481559 0.0357718033078858 0.0575892118674823 0.9957425588570659 0.013338274201290292 0.013860312341996646 2.732032627772344e-07 6.563514118322543 -0.32225096733362757 S(ph)ESEVEEAAAIIAQRPDNPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SESEVEEAAAIIAQRPDNPR 20 1 Q16643-3;Q16643;Q16643-2;D6R9W4;D6R9Q9 Q16643-3 DBN1 Drebrin 1 S(0.71)ES(0.29)EVEEAAAIIAQRPDNPR 65.416 0.0030416999999999996 944180.0 3184.8 2053.1 4624.8 3283.2 3920.5 4365.0 5185.5 3168.0 1702.0 4017.4 True False 3723.9237373327414 2256.9181995347967 4735.072771651673 3099.2529482780164 3152.3061685447337 4136.091715856665 4694.291900231105 3084.843356773461 1726.8885301323457 4745.7228182791005 0.7846905265915035 0.47556890403329605 0.9977558641675391 0.653062360983373 0.6642415263704395 0.871540937857913 0.9891626797397649 0.6500260286781963 0.3638831419906972 1.0 12.212412124685727 S(ph)ESEVEEAAAIIAQRPDNPR ddPTM_PC-9_Lapatinib_30min_R1 1 SESEVEEAAAIIAQRPDNPR 20 1 Q16643-3;Q16643;Q16643-2;D6R9W4;D6R9Q9 Q16643-3 DBN1 Drebrin 1 S(0.955)ES(0.045)EVEEAAAIIAQRPDNPR 67.29899999999999 0.0026429 985590.0 2656.5 1123.6 957.7 746.51 2611.6 1967.4 954.67 3135.5 1201.5 966.81 True False 2618.6178228575636 1120.998373233778 878.9616028289079 801.4108356843583 2457.990822603151 1883.2588882333991 1004.0981413638152 3281.186776705514 1066.1744176440964 1133.9218203066528 2.3093460024866586 0.9886028764581144 0.775151855346787 0.7067602204423832 2.167689851791037 1.6608366242781174 0.8855091447947191 2.893662259553454 0.9402539033561986 1.0 10.14710545991224 -6.256580535737435 24.998745437293746 1.654193164885088 1.1502384273681667 0.064176305122847 0.7096181560025754 1003.3304092904984 5162129.093287745 0.2074365321277653 0.2593822847186826 5.538848217979488e-07 6.256580535737435 -0.5039547375169213 S(ph)ESLELPQAAPPQIYHEK ddPTM_PC-9_Lapatinib_30min_R1 1 SESLELPQAAPPQIYHEK 18 0 B0QY58;B0QY55;B0QY57;B0QY56;H0YGT9;Q15040 B0QY58 JOSD1 Josephin-1 1 S(0.536)ES(0.464)LELPQAAPPQIYHEK 81.312 0.0018027000000000002 6874000.0 24461.0 27313.0 32803.0 29385.0 28941.0 24759.0 22888.0 26995.0 32442.0 24430.0 True False 24112.181654401982 27249.758426605727 30106.06396324178 31546.070925486405 27238.747280195214 23700.11528604794 24073.028648155887 28249.28625009261 28788.040330594882 28652.69294907118 0.841532825457637 0.9510365561464291 1.0507237144080628 1.1009810136016907 0.9506522590602848 0.8271514069610765 0.8401663568218376 0.9859208103163075 1.0047237228893031 1.0 14.806383117892612 -3.4214658402457085 15.994150049754412 0.9545916142862106 0.41485472589736794 0.0 0.08852824290248855 0.0 0.0 0.022362196489857874 0.0 0.00037890833589230205 3.4214658402457085 -0.5397368883888427 S(ph)ESLIDASEDSQLEAAIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SESLIDASEDSQLEAAIR 18 0 C9JAT7;O94888 C9JAT7 UBXN7 UBX domain-containing protein 7 1 S(0.555)ES(0.428)LIDASEDS(0.017)QLEAAIR 139.67 0.00013991 1444700.0 3550.3 1622.6 3781.5 1225.2 5165.1 4083.5 5284.2 5418.9 3573.0 1458.0 True False 4151.295668378686 1783.6810046101807 3871.6653014186104 1156.5560161519943 4153.035732980588 3869.354071409095 4783.642321704983 5276.659616799147 3625.2483655481 1722.3238584783496 2.410287500776016 1.035624627638869 2.247931062651118 0.6715090257030965 2.411297801244965 2.2465891373226508 2.7774348582334962 3.063686072061387 2.1048587045359515 1.0 10.750140731165734 S(ph)ESLSNCSIGK ddPTM_PC-9_AZD4547_30min_R2 1 SESLSNCSIGK 11 0 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 S(0.933)ES(0.042)LS(0.025)NCSIGK 152.0 0.00037752 30008000.0 25822.0 29314.0 39521.0 44396.0 46979.0 37821.0 40834.0 41042.0 37836.0 36484.0 True False 34032.85886903421 38789.177233486385 38996.925717437334 34161.18811136246 40456.776766567666 35456.04689114372 44468.14689406023 34699.90195133602 39835.9337162751 35206.706264865315 0.9666584148201743 1.1017553571092282 1.1076561784580934 0.9703034374861067 1.1491213197339532 1.0070821912280739 1.2630589910774301 0.9856048927236608 1.1314870927312375 1.0 15.103562642887503 -6.277445730250974 24.904479014880685 1.093240469062899 1.0463236812321368 0.07210133310378186 0.0894909147801435 2447.374804031725 3807889.841334428 0.026374326295059206 0.02999586792790268 5.279031698177054e-07 6.277445730250974 -0.04691678783076214 S(ph)ESLSNCSIGK ddPTM_PC-9_Lapatinib_30min_R1 2 SESLSNCSIGK 11 0 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 S(0.975)ES(0.025)LSNCSIGK;S(0.475)ES(0.263)LS(0.263)NCSIGK 182.25 0.00027039999999999996 83263000.0 106739.0 137637.0 142084.0 139098.0 135217.0 105193.0 121270.0 124293.0 127829.0 110550.0 True False 105216.88228646477 137318.30998289233 130402.40198010071 149327.73093732563 127263.80190685042 100694.14060685992 127548.76722133278 130068.10653390449 113431.55192095487 129658.42020138461 0.8114928604177237 1.059077457288238 1.0057380136018976 1.151700990227945 0.9815313321663577 0.7766108861303603 0.983729147888929 1.0031597356491275 0.8748490976889408 1.0 16.984356374328947 -6.530497850658808 24.999348422183903 0.9255598776790493 1.017629748254177 0.11931647847296967 0.10101037542950593 354.4069231870379 1162848.3222545101 0.033270009519815215 0.03333131729923764 2.947828065492344e-07 6.530497850658808 0.09206987057512761 S(ph)ESPPAELPSLR ddPTM_PC-9_AZD4547_30min_R2 1 SESPPAELPSLR 12 0 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 S(0.999)ES(0.001)PPAELPSLR 171.49 0.0011077 107520000.0 24809.0 33448.0 36361.0 40483.0 28787.0 32675.0 28951.0 36185.0 26400.0 28614.0 True False 32697.74594074314 44259.411888710245 35878.82938214467 31150.26980611511 24790.42194978998 30631.827084638713 31527.582914481496 30593.439698579346 27795.450103331797 27612.23256942375 1.1841761023319355 1.6028914640433911 1.2993816886025684 1.1281329652644307 0.8978057781985189 1.1093571303089302 1.1417976737380295 1.1079668991509515 1.0066353755875188 1.0 14.753019920377278 -5.727654679126735 3.239475342456378 1.0553757711509575 1.4030814513263903 0.6021658065438511 0.1161600282965119 0.15049019902472002 3.2383277330741045 0.032084619948905053 0.05692617667303509 1.8721701686664343e-06 5.727654679126735 0.3477056801754328 S(ph)ESPPAELPSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SESPPAELPSLR 12 0 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 S(0.83)ES(0.17)PPAELPSLR 157.03 0.00040092 7629200.0 36164.0 44064.0 49444.0 54033.0 61159.0 39524.0 52360.0 34196.0 36279.0 33857.0 True False 42285.850928441745 48438.38271116908 50622.9324774142 51005.706187349555 49175.33298355496 37451.29186197452 47400.081746427626 33298.39123365697 36809.51174187505 39995.006088135466 1.0572782720737193 1.211110772290602 1.265731335703722 1.275301873312639 1.2295368295528986 0.9363992039267237 1.1851500070277243 0.8325637245879792 0.920352697553273 1.0 15.28753225100785 -7.1118827434134255 1.2208309464983584 0.9318031613675962 1.213469971684429 0.5103359187363954 0.10754692110255883 0.3694004250106848 1.1029861929463347 0.06521016238117176 0.04256606920886179 7.728892318175634e-08 7.1118827434134255 0.2816668103168328 S(ph)ESPPAELPSLR ddPTM_PC-9_Lapatinib_30min_R1 1 SESPPAELPSLR 12 0 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 S(0.944)ES(0.056)PPAELPSLR 149.23 0.00015902 3264100.0 5715.2 9640.2 8469.4 7300.7 5878.0 9347.5 6678.8 6670.2 8104.1 5092.1 True False 5633.700199960684 9617.878709192126 7773.078624829437 7837.6178324212515 5532.267596592635 8947.729215086769 7024.59558438062 6980.121842762275 7191.330918043714 5972.262700203249 0.9433108492981993 1.6104245898066087 1.3015299250926962 1.3123364168415634 0.9263269005906857 1.4982142722526688 1.1762033817001314 1.1687566661333781 1.2041216669519539 1.0 12.54406191094247 -9.468011556682441 0.3053690879689791 0.9311775746651566 1.2985356167315356 0.11695398936409795 0.20168867712121594 10.818923222205363 1.5520384323719 1.1397602744828947 0.23786938103669386 3.4039913147629176e-10 9.468011556682441 0.367358042066379 S(ph)ESPPAELPSLRR ddPTM_PC-9_AZD4547_30min_R2 1 SESPPAELPSLRR 13 1 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 S(0.823)ES(0.177)PPAELPSLRR 78.191 0.007002199999999999 18730000.0 13575.0 9261.3 19452.0 32767.0 25131.0 15695.0 11331.0 18239.0 12201.0 18638.0 True False 17891.567622459126 12254.83411040756 19194.053770288996 25213.074395103493 21641.99444263634 14713.589168887665 12339.437048944415 15420.581640524772 12845.919951164822 17985.48929296569 0.9947779196341744 0.6813734066829393 1.0671966415612606 1.4018564624185448 1.2033030678292833 0.8180811169058549 0.6860773620304285 0.8573901654460921 0.7142380027541978 1.0 14.134545787893083 -6.839549729521802 8.166978578941086 0.7964713942144327 1.066078399002561 0.3148202486346693 0.18682029326668498 0.350360212960522 32.307884187446206 0.07333722615995271 0.06475357074995106 1.4469391597340038e-07 6.839549729521802 0.2696070047881284 S(ph)ESPPPLSDPK ddPTM_PC-9_AZD4547_30min_R2 1 SESPPPLSDPK 11 0 Q15059;Q15059-2 Q15059 BRD3 Bromodomain-containing protein 3 1 S(0.693)ES(0.307)PPPLSDPK 105.25 0.0054284 0.0 27996.0 30135.0 33133.0 49892.0 46168.0 38539.0 36711.0 33707.0 35789.0 31141.0 True False 36898.145647025056 39875.54942795635 32693.6347712824 38390.17022371604 39758.37011768867 36129.15023764013 39978.20788136957 28498.357659804176 37680.7334753084 30050.763068582684 1.2278605226368158 1.3269396632941155 1.0879469082588047 1.2775106620787275 1.323040284433078 1.2022706430177892 1.3303558312356394 0.9483405660869387 1.2539027175220938 1.0 14.875114004804809 -7.7515215458258275 24.999998921437633 1.075841211581613 1.251749296009216 0.4179851576305734 0.10056985091707094 190.70838308808308 480723.6837531347 0.045260856439758294 0.025726516539584555 1.772060129106725e-08 7.7515215458258275 0.17590808442760308 S(ph)ESPSLTQER ddPTM_PC-9_Lapatinib_30min_R1 1 SESPSLTQER 10 0 H7BZJ7;Q9BXW9-3;Q9BXW9;Q9BXW9-1 H7BZJ7 FANCD2 Fanconi anemia group D2 protein 1 S(0.56)ES(0.303)PS(0.032)LT(0.106)QER 91.961 0.007737000000000001 8959600.0 18023.0 19652.0 18765.0 15046.0 23244.0 20321.0 18733.0 23976.0 22819.0 14730.0 True False 17765.988714986597 19606.497001415293 17222.214134994734 16152.533031984627 21876.833619462283 19451.918200564673 19702.90307872703 25090.012488691264 20248.883925277267 17276.060873508748 1.0283587702697383 1.1348939520976136 0.9968831587878587 0.9349662026690965 1.2663091302837672 1.1259463799639884 1.1404742795818474 1.4522993796094161 1.1720775976384217 1.0 14.076486684661205 -6.268903506578883 24.995533215232097 1.2095020194966437 1.0297916673286733 0.32248684066400657 0.11846478843282761 667.2426146019133 2234427.6321033733 0.03673552364090715 0.042451299143633985 5.383893909052069e-07 6.268903506578883 -0.17971035216797038 S(ph)ESVEGFLSPSR ddPTM_PC-9_AZD4547_30min_R2 2 SESVEGFLSPSR 12 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 S(0.999)ES(0.001)VEGFLSPSR;S(0.924)ES(0.076)VEGFLSPSR 118.76 0.00057008 6730300.0 15703.8 18674.0 23746.6 28043.0 28690.8 29799.0 18476.3 27898.2 23466.0 27001.2 True False 20697.281740668386 24710.005310026758 23431.70456824718 21578.119610031048 24707.577659257102 27935.66381928536 20120.654906664167 23587.174226859384 24706.36485321153 26055.896206525646 0.7943415792194012 0.9483460140525962 0.8992860726233151 0.8281472814827552 0.9482528431729452 1.0721436560024726 0.7722112011493579 0.9052528471828969 0.9482062968543707 1.0 14.669322257442074 -4.7528454925762125 24.820333436302253 0.9184635174324973 0.7943413223108998 0.19161373563048745 0.0793850411447935 548.6629505140728 1584482.9870276728 0.019738297792819864 0.22505403308383365 1.7666662295409755e-05 4.7528454925762125 -0.1241221951215975 S(ph)ESVEGFLSPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SESVEGFLSPSR 12 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 S(0.992)ES(0.008)VEGFLSPSR;S(0.895)ES(0.103)VEGFLS(0.001)PSR 153.81 0.00023464 6754900.0 11644.8 11281.400000000001 14489.5 16792.4 20022.6 16782.2 15234.4 18710.0 15540.0 9825.5 True False 13616.034644716246 12401.342835824773 14834.984631734751 15851.576269695348 16099.315263436753 15902.111888625375 13791.287344495368 18218.88232488365 15767.24310120837 11606.7853713848 1.1731098843513572 1.0684562899214853 1.2781303485036182 1.3657163256223892 1.387060650154501 1.3700702976579726 1.1882090435217496 1.569675128981037 1.3584504750196125 1.0 13.502680836598966 -5.424388194673862 4.139139762078013 1.342115731653391 1.1227472683172381 0.22219537293086122 0.14215925737021043 0.2790688012257713 8.2689035045896 0.03609832802002511 0.07894428893502717 3.763672322577755e-06 5.424388194673862 -0.21936846333615279 S(ph)ESVEGFLSPSR ddPTM_PC-9_Lapatinib_30min_R1 3 SESVEGFLSPSR 12 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 S(0.989)ES(0.011)VEGFLSPSR;S(0.975)ES(0.025)VEGFLSPSR;S(0.975)ES(0.02)VEGFLS(0.005)PSR 140.91 7.683399999999999e-05 7128400.0 28014.0 21551.9 30569.0 27686.2 27865.5 26560.5 23160.9 23100.7 34878.3 29028.8 True False 27614.515222861573 21501.997899694783 28055.734819752408 29722.335506455725 26226.506075680863 25424.569330549562 24360.058074845932 24174.04285525149 30949.938569218528 34046.389401555374 0.8110849845828302 0.6315500197713325 0.8240443498678515 0.8729952288302821 0.7703168099957974 0.7467625724032889 0.715496077646726 0.7100324962548634 0.9090520056086949 1.0 15.055214188986028 -8.459414958374474 3.973579810678174 0.998556642331835 0.7608395784546336 0.6091655175142106 0.0641337577226255 0.13707061373703228 4.269466236725345 0.06470778307847475 0.01698975187805874 3.472042572343153e-09 8.459414958374474 -0.23771706387720148 S(ph)ESWSEELQPGHPR ddPTM_PC-9_Lapatinib_30min_R1 1 SESWSEELQPGHPR 14 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 S(0.847)ES(0.135)WS(0.018)EELQPGHPR 114.59 9.7109e-05 1070400.0 3086.7 2842.2 3668.3 3346.2 3613.3 3977.9 3181.3 4843.9 4930.1 4965.6 True False 3042.6830919685453 2835.619060524249 3366.7065340474915 3592.290710595972 3400.7727980211266 3807.7744899378085 3346.0121477795506 5068.965277526342 4374.820221745451 5823.897343753903 0.5224479265988102 0.4868937230779719 0.5780848004915926 0.6168190300347041 0.583934193426063 0.6538189575098924 0.5745314435131879 0.8703733905891694 0.7511842952447334 1.0 12.507769210431796 -8.169710450972252 0.38058326008998966 1.0279004302145287 0.5008617265006937 0.8406538551396441 0.061662498163542065 0.43427334636984294 0.18863062569828487 0.0861517435103337 0.060293753430291995 6.765338778286672e-09 8.169710450972252 -0.527038703713835 S(ph)ETPPHWR ddPTM_PC-9_Lapatinib_30min_R1 1 SETPPHWR 8 0 Q13427;E9PG73;C9JM79 Q13427 PPIG Peptidyl-prolyl cis-trans isomerase G 1 S(0.923)ET(0.077)PPHWR 101.9 0.0044453 4424700.0 53028.0 42624.0 55323.0 48021.0 51079.0 53606.0 40860.0 45269.0 61254.0 43024.0 True False 52271.81099585581 42525.30674681073 50774.556492955715 51552.62453335999 48074.63364517782 51313.39634168935 42975.53087048454 47372.363002609454 54354.92948678442 50460.64107412356 1.0358927251651788 0.8427421023911228 1.006220995456063 1.0216403009552013 0.9527154753059748 1.016899414066364 0.8516643854634376 0.9387982790988006 1.0771747708662756 1.0 15.622870914610866 -8.252311038352829 24.858125222618167 1.0385873877046874 0.9563867886939147 0.18968554683696615 0.06626246813419724 870.1592105069307 2369619.9767771726 0.04546866074294919 0.016642580928325622 5.593568509496376e-09 8.252311038352829 -0.0822005990107727 S(ph)EY(ph)NIT(ph)ITITDLGT(ph)PRLKT(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEYNITITITDLGTPRLKTK 20 2 Q9Y5E6 Q9Y5E6 PCDHB3 Protocadherin beta-3 5 S(0.992)EY(0.991)NIT(0.966)IT(0.055)IT(0.128)DLGT(0.896)PRLKT(0.972)K 45.70399999999999 0.045047000000000004 0.0 1475.6 4572.5 3607.1 4330.7 5365.8 4455.7 4694.5 4994.8 1548.5 1673.9 True False 1725.3899355715248 5026.427581400253 3693.106944002926 4088.0649193188347 4314.410008717596 4222.03524818844 4249.8029747632645 4863.691792428055 1571.143883025814 1977.3648194148898 0.8725703616402332 2.5419829118268593 1.8676912362058364 2.0674307943480605 2.181898841506772 2.135182747631647 2.1492255415067 2.4596835873044616 0.7945644969504018 1.0 10.949363354315434 -8.270556523524666 24.991999089349267 0.8972820081883783 2.0590136731908855 0.5222625030794212 0.434541292125034 523.9901068983753 1436349.0567278138 0.37087521643632737 0.10121107268529118 5.3634406159705635e-09 8.270556523524666 1.1617316650025071 S(ph)FADIGK ddPTM_PC-9_AZD4547_30min_R2 2 SFADIGK 7 0 Q9Y6M7-7;Q9Y6M7-2;C9JRP1;Q9Y6M7;Q9Y6M7-13;Q9Y6M7-9;Q9Y6M7-11;Q9Y6M7-6;Q9Y6M7-14;Q9Y6M7-3;Q9Y6M7-4;Q6U841-2;Q6U841-3;Q6U841;F8WDX9;Q6U841-4;E7EW28;C9J240 Q9Y6M7-7 SLC4A7;SLC4A10 Sodium bicarbonate cotransporter 3;Anion exchange protein;Sodium-driven chloride bicarbonate exchanger 1 S(1)FADIGK;S(1)FADIGK 84.615 0.019837 7556400.0 50814.0 68974.0 81889.0 81315.0 75538.0 66495.0 89574.0 98734.0 70155.0 62962.0 True False 66971.79500314085 91268.49663991576 80803.09835467799 62569.08305422645 65050.85258079113 62337.05713827243 97545.9124721689 83476.9289816092 73863.25007572897 60757.7195441413 1.1022763116460443 1.5021712026832734 1.3299231597389605 1.0298128949485863 1.070659877771265 1.025994023573971 1.6054900217461336 1.3739312404732718 1.2157014883033312 1.0 15.890780100869032 -7.223152187607414 24.99771998136192 1.3299422697127201 1.18704912013253 0.07390315383152335 0.19770795439017366 1361.9711012671116 889232.8259161497 0.07878352690057451 0.061024408870960146 5.982019334647548e-08 7.223152187607414 -0.14289314958019017 S(ph)FADIGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFADIGK 7 0 Q9Y6M7-7;Q9Y6M7-2;C9JRP1;Q9Y6M7;Q9Y6M7-13;Q9Y6M7-9;Q9Y6M7-11;Q9Y6M7-6;Q9Y6M7-14;Q9Y6M7-3;Q9Y6M7-4;Q6U841-2;Q6U841-3;Q6U841;F8WDX9;Q6U841-4;E7EW28;C9J240 Q9Y6M7-7 SLC4A7;SLC4A10 Sodium bicarbonate cotransporter 3;Anion exchange protein;Sodium-driven chloride bicarbonate exchanger 1 S(1)FADIGK 76.221 0.031573000000000004 2775500.0 28882.0 31974.0 27728.0 22278.0 45806.0 28059.0 31370.0 31797.0 24046.0 22332.0 True False 33771.15215449767 35148.167411195565 28389.140679025593 21029.835886250494 36830.643121122324 26587.536644953514 28398.406500867753 30962.362441706333 24397.62725943735 26380.614819985258 1.2801503067666768 1.3323483038980668 1.0761364309644037 0.7971700443584372 1.3961252750341664 1.007843707448831 1.0764876669725632 1.1736785762191586 0.924831639668775 1.0 14.687190567619105 -5.26797157345223 20.888745284496828 1.0645758062095123 1.3062493928367396 0.3090665668891317 0.14895944594546445 58.76140520184221 187918.38231873343 0.037751517108034933 0.0823488863198576 5.395459370932602e-06 5.26797157345223 0.24167358662722727 S(ph)FADIGK ddPTM_PC-9_Lapatinib_30min_R1 1 SFADIGK 7 0 Q9Y6M7-7;Q9Y6M7-2;C9JRP1;Q9Y6M7;Q9Y6M7-13;Q9Y6M7-9;Q9Y6M7-11;Q9Y6M7-6;Q9Y6M7-14;Q9Y6M7-3;Q9Y6M7-4;Q6U841-2;Q6U841-3;Q6U841;F8WDX9;Q6U841-4;E7EW28;C9J240 Q9Y6M7-7 SLC4A7;SLC4A10 Sodium bicarbonate cotransporter 3;Anion exchange protein;Sodium-driven chloride bicarbonate exchanger 1 S(1)FADIGK 76.221 0.031573000000000004 3403500.0 34279.0 36118.0 16268.0 17102.0 18884.0 12135.0 12991.0 12169.0 20315.0 9004.0 True False 33790.175174001284 36034.37099008332 14930.50783629599 18359.738130599562 17773.280247372462 11616.014338066647 13663.610414548823 12734.41616511861 18026.91077356622 10560.32940292415 3.199727383943611 3.412239298151573 1.4138297458942655 1.7385573337812512 1.6830232816839075 1.0999670459948132 1.2938621413424258 1.2058730063469854 1.707040574754664 1.0 13.366367216192149 -5.263480564231734 24.979072925107804 1.4088478887122855 3.305983474938192 0.9053046500869998 0.2474650305624235 44.57952823839701 545551.7415517658 0.06573847185853132 0.14871844348052093 5.451542921660696e-06 5.263480564231734 1.8971355862259063 S(ph)FAGNLNTYK ddPTM_PC-9_AZD4547_30min_R2 2 SFAGNLNTYK 10 0 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 1 S(1)FAGNLNTYK;S(1)FAGNLNTYK 115.57 0.0011127 206941000.0 94578.0 106562.0 133655.0 121497.0 116495.0 148782.0 129547.0 135614.0 136883.0 121729.0 True False 124651.83665539154 141006.08256651362 131882.64737137442 93487.74375993802 100321.68010007263 139478.6380200985 141076.43203420757 114657.97239969959 144118.35592781682 117467.30476142373 1.0611619710570495 1.2003857826898914 1.1227179140547088 0.7958618268275736 0.8540391754439766 1.1873826364142757 1.2009846682081793 0.9760841336452735 1.2268805879263291 1.0 16.8418997348665 -6.804637007850305 24.999807365181645 1.1219415104142947 1.0123025144317217 0.14653884295381414 0.13399061426863945 320.2710064948946 185348.547010499 0.05155823669178599 0.04547039206342014 1.5680611398927878e-07 6.804637007850305 -0.10963899598257298 S(ph)FAGNLNTYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SFAGNLNTYK 10 0 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 1 S(1)FAGNLNTYK;S(1)FAGNLNTYK;S(1)FAGNLNTYK 153.81 0.00017976 138743000.0 248414.0 392471.0 333170.0 250655.0 331327.0 222269.0 311110.0 241010.0 222541.0 204647.0 True False 290465.5837998536 431432.9271295211 341114.03635426075 236611.612984474 266405.85280077043 210612.82235778787 281639.408558653 234683.7428712028 225795.2411187915 241747.8811152391 1.2015227701681122 1.7846399527442425 1.411032166158489 0.9787536167553141 1.1019987086206438 0.8712085557324516 1.165012935209132 0.97077890316371 0.9340112520413649 1.0 17.88314371918367 -5.694787825262944 4.591226530790764 1.0065163085498876 1.5146249176670628 0.6584876997083321 0.15281050890544542 0.10984311153944491 4.473041064256935 0.03958003278604619 0.06930464914660245 2.019352678261516e-06 5.694787825262944 0.5081086091171751 S(ph)FAGNLNTYK ddPTM_PC-9_Lapatinib_30min_R1 1 SFAGNLNTYK 10 0 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 1 S(1)FAGNLNTYK 128.57 0.00027537 74488000.0 91548.0 171900.0 147730.0 115680.0 173860.0 160510.0 140770.0 168270.0 157830.0 146580.0 True False 90242.50873215286 171501.97611150466 135584.2096542908 124187.49309716724 163633.89662191144 153645.36146708505 148058.38180710012 176088.4384998363 140053.52337641935 171916.1576944273 0.5249216242521809 0.9975907931605892 0.7886647274614247 0.7223724329501625 0.9518238356208659 0.8937226350776306 0.8612243537356551 1.0242692767297943 0.8146617819679157 1.0 17.39134561861377 -4.750557167590674 24.97429310556345 0.8876583339806929 0.5249208412525522 0.5751348313452158 0.09522016312753415 348.6359888857411 800054.7415602357 0.023512831630875475 0.3407634018376589 1.775999472332624e-05 4.750557167590674 -0.3627374927281407 S(ph)FAGNLNTYKR ddPTM_PC-9_AZD4547_30min_R2 1 SFAGNLNTYKR 11 1 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 1 S(1)FAGNLNTYKR 84.17299999999999 0.005571 52450000.0 47450.0 39089.0 57621.0 71186.0 76113.0 57096.0 47201.0 68270.0 39908.0 66782.0 True False 62538.11297868765 51723.75482294295 56856.907891107454 54775.16751273643 65546.02375601369 53525.77809409434 51401.797559546874 57720.44018853145 42017.455406203226 64443.98250685878 0.9704259505071976 0.8026157417791178 0.8822686879268544 0.8499655884380936 1.017100762651309 0.8305783722847604 0.7976198173984076 0.8956684230740746 0.6519996712141635 1.0 15.975758031963894 -6.954556592931898 24.99985936207301 0.8256942556555503 0.8974829924086898 0.10430445893935014 0.09866869791418151 285.4660084481138 157042.9757405289 0.03300367996177272 0.029106501620693986 1.1103078416455594e-07 6.954556592931898 0.07178873675313946 S(ph)FAGNLNTYKR ddPTM_PC-9_Lapatinib_30min_R1 2 SFAGNLNTYKR 11 1 Q01813;B1APP6;Q01813-2 Q01813 PFKP ATP-dependent 6-phosphofructokinase, platelet type 1 S(1)FAGNLNTYKR;S(1)FAGNLNTYKR 104.41 0.0012314 92504000.0 175208.0 96508.0 105540.0 90427.0 90950.0 97858.0 70879.0 63612.0 103441.0 68561.0 True False 172709.50179078817 96284.54165543406 96862.90859618157 97077.3032356291 85600.49981457992 93672.8414581398 74548.76780638937 66567.64574702321 91790.38529797994 80411.67749821015 2.147816177502732 1.1973950133993563 1.204587587397833 1.2072538001435165 1.0645282187588396 1.1649158974481637 0.9270888274659949 0.827835555955227 1.1415056637765462 1.0 16.295117406394212 -2.503103858087756 1.118255355536386 1.043073366885814 199.99999999980764 0.8810383126028069 0.1181308074351641 94.44723739274383 0.866155783207072 0.03794361698006042 47363.89241507634 0.00313975775587431 2.503103858087756 198.95692663292184 up S(ph)FCISTLANTK ddPTM_PC-9_AZD4547_30min_R2 1 SFCISTLANTK 11 0 E9PEI0;Q69YH5 E9PEI0 CDCA2 Cell division cycle-associated protein 2 1 S(0.999)FCIS(0.001)T(0.001)LANTK 93.766 0.006923100000000001 3636100.0 14274.0 8574.9 12077.0 19073.0 16878.0 15752.0 11887.0 21161.0 12505.0 12554.0 True False 18812.835082355916 11346.568733691147 11916.851089028389 14676.014524912525 14534.781035486689 14767.02494987693 12944.919971829702 17891.053681404937 13165.988770536522 12114.488281140208 1.55292032529708 0.9366114746551404 0.9836858819353105 1.211443206211202 1.199784976317521 1.2189557335959607 1.0685486395642734 1.4768311517753223 1.086796938095461 1.0 13.564445845844846 S(ph)FDASDTLALPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFDASDTLALPR 12 0 Q5JXC2 Q5JXC2 MIIP Migration and invasion-inhibitory protein 1 S(0.999)FDAS(0.001)DTLALPR 93.766 0.0051393 1568600.0 4976.2 6108.6 5227.9 6514.0 7045.8 4934.4 6918.5 4970.6 5238.6 2913.1 True False 5818.572375569954 6715.0214376690155 5352.55296292116 6149.041698672945 5665.2260686985 4675.631377485251 6263.129594397623 4840.127016786034 5315.204614542482 3441.221969913089 1.6908448296687197 1.9513479503441067 1.5554221755292184 1.7868773803127393 1.646283244216757 1.3587125208326325 1.8200306894343707 1.4065140403913774 1.5445689528352982 1.0 11.748705238220424 -11.887440325473621 0.14862704070123717 8.333952767020612e-13 1.9175672096476646 0.6518662842811961 0.15297132922069612 30.967074515736318 0.5863611874490398 11.324912077703113 0.8977025811128998 1.2958647444541634e-12 11.887440325473621 1.9175672096468312 S(ph)FDASDTLALPR ddPTM_PC-9_Lapatinib_30min_R1 1 SFDASDTLALPR 12 0 Q5JXC2 Q5JXC2 MIIP Migration and invasion-inhibitory protein 1 S(0.989)FDAS(0.005)DT(0.005)LALPR 72.891 0.023955 2230100.0 4896.8 5435.3 4541.5 5786.2 6864.4 5572.3 5217.7 5076.5 6926.2 5787.7 True False 4826.970734036859 5422.714896793839 4168.115400696967 6211.7364501973625 6460.649487929652 5333.985718665736 5487.846975597824 5312.37272267439 6146.098419880598 6788.096233374514 0.7110934447724033 0.7988565144572335 0.614033045112695 0.9150925733280847 0.9517616229665501 0.7857852239101351 0.8084515579811827 0.7826012684610235 0.905422994692171 1.0 12.728791302463708 -14.522878715558049 0.028594079708020623 2.179190464927512 3.502472956402288e-11 0.3972440584479777 0.08610372593517723 1868.0586494940628 4.010056535933718 233.80776778418883 98.54918474747818 3.0000002053143045e-15 14.522878715558049 -2.179190464892487 S(ph)FDEQNVPK ddPTM_PC-9_AZD4547_30min_R2 1 SFDEQNVPK 9 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 S(1)FDEQNVPK 136.48 0.00099956 3776100.0 16667.0 18850.0 21743.0 17354.0 21680.0 20663.0 18603.0 26296.0 25058.0 18264.0 True False 21966.759304863794 24942.893868159183 21454.673613376177 13353.30341662728 18670.10622404026 19370.939343531427 20258.630961213745 22232.55742196609 26382.514723079108 17624.582919128945 1.2463704477807553 1.4152331424017568 1.217315252895444 0.7576521656086507 1.0593218750031554 1.0990863972450131 1.1494530709845008 1.261451548895143 1.4969156912328796 1.0 14.105301496486467 -10.591715746268033 14.580569426935265 0.999958401100492 1.1784680067404576 0.07793572135461702 0.1920671384005616 0.0 0.0 0.20253119682081405 0.04912103041029272 2.5602610766230354e-11 10.591715746268033 0.17850960563996565 S(ph)FDEQNVPK ddPTM_PC-9_Lapatinib_30min_R1 2 SFDEQNVPK 9 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 S(1)FDEQNVPK;S(1)FDEQNVPK 141.71 0.00070245 7545300.0 31173.0 40525.0 41244.0 38396.0 39493.0 38536.0 42748.0 40807.0 46255.0 66643.0 True False 30728.467303571917 40431.16685234857 37853.07752644407 41219.76992530122 37170.09938622543 36887.90511180354 44961.28227242956 42703.04219327762 41045.274813256474 78162.1537537845 0.39313741789112466 0.5172729372287922 0.4842890799258621 0.5273622584038047 0.4755511152278824 0.47194074549177173 0.5752308516735646 0.546339118645512 0.5251297826637629 1.0 16.254182600784794 -14.522878745280336 0.2581416113519164 4.173782429577444 0.46424869886769843 0.9350178359569595 0.039972690401299096 42.661807932100494 0.4192935581870009 71.68442872822347 0.05280899663878521 3.0000000000000132e-15 14.522878745280336 -3.7095337307097456 S(ph)FDGNTLLNR ddPTM_PC-9_AZD4547_30min_R2 1 SFDGNTLLNR 10 0 Q05209-2;Q05209-3;Q05209 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 S(1)FDGNTLLNR 120.03 0.00073983 3030200.0 6756.6 7325.0 7839.0 8927.3 11478.0 9480.1 7836.3 13614.0 9491.6 8462.5 True False 8905.05825398949 9692.663001817822 7735.049738088389 6869.248910410085 9884.477824701751 8887.307848357566 8533.715519075386 11510.269118597747 9993.306598514551 8166.230450784533 1.0904735431675183 1.1869200924750591 0.9471995414169679 0.8411774504539182 1.2104088764421466 1.0882999080075875 1.0450005752967146 1.4094959954861366 1.2237355605797888 1.0 12.995454565611487 -7.71265205787725 24.999795934195774 1.237462741196206 1.0577861656782748 0.19977393019864986 0.1369136737789026 148.50474841815156 76097.13446240244 0.06500047360149011 0.03752793774864029 1.9379739816831466e-08 7.71265205787725 -0.17967657551793126 S(ph)FDGNTLLNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SFDGNTLLNR 10 0 Q05209-2;Q05209-3;Q05209 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 S(1)FDGNTLLNR;S(1)FDGNTLLNR;S(0.987)FDGNT(0.013)LLNR;S(0.997)FDGNT(0.003)LLNR 140.91 0.00012393 13099500.0 46429.0 66481.0 66648.4 71902.5 70315.2 73463.0 69123.0 54834.0 67147.1 48341.7 True False 54288.51268545024 73080.79432237739 68237.55062146464 67874.0360360502 56537.44132188668 69610.47095577962 62575.169032817335 53394.66560142545 68128.99930766721 57105.66753731336 0.9506676837281979 1.279746783007584 1.1949348210819462 1.188569172958195 0.9900495653070618 1.218976573740172 1.095778610624421 0.9350151728204016 1.1930339359600535 1.0 15.801346314668509 -7.525229616315052 24.951588953272214 1.0414941069258101 1.1432037266880675 0.12354998357219493 0.11210255550644567 145.37833450953423 1542947.639576731 0.050317617545042014 0.029300051413832014 2.983804631163794e-08 7.525229616315052 0.10170961976225734 S(ph)FDGNTLLNR ddPTM_PC-9_Lapatinib_30min_R1 3 SFDGNTLLNR 10 0 Q05209-2;Q05209-3;Q05209 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 S(1)FDGNTLLNR;S(0.998)FDGNT(0.002)LLNR;S(0.999)FDGNT(0.001)LLNR 120.03 0.00073983 13428400.0 35735.2 32756.8 36663.0 34625.0 37941.2 38005.0 34312.4 33342.7 39501.0 37591.9 True False 35225.609494966906 32680.953642171786 33648.7096632727 37171.43800561399 35709.57321126923 36379.6147439821 36088.92818013738 34891.92356551073 35051.98141602949 44089.60982694185 0.7989548928473752 0.7412393480107738 0.7631891004558397 0.8430883863911999 0.8099317129689855 0.8251289790673447 0.8185358936445953 0.7913865353416967 0.7950168203713671 1.0 15.428151089362562 -14.522878745209068 0.30274850542939974 2.6957578391467107 0.7886913519455596 0.8244310291111101 0.027907762546638785 120.03951207611416 1.1038028544866298 129.40288083014985 0.03042384155766749 3.0000000004923114e-15 14.522878745209068 -1.9070664872011511 S(ph)FDHLISDTK ddPTM_PC-9_AZD4547_30min_R2 2 SFDHLISDTK 10 0 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 S(0.997)FDHLIS(0.003)DTK;S(1)FDHLISDTK 159.44 0.0004798 22309000.0 80620.0 76700.0 70577.0 115427.0 92698.0 92958.0 66755.0 104072.0 77672.0 83698.0 True False 106255.48299982739 101491.77504975107 69641.1028658074 88817.08847937285 79828.48278395235 87145.32156492244 72696.06567842947 87990.06373664629 81777.58334946922 80767.75849568848 1.3155680556059939 1.2565877392173619 0.8622388953572974 1.0996601878472838 0.9883706601590748 1.078961743993111 0.900062933928148 1.089420647241849 1.012502821331047 1.0 16.30149188117518 -5.131501058394072 6.104551065867968 1.0094379411485046 1.3002698628335374 0.7032066290434996 0.07358357424217764 0.10976389144648517 4.885961709461999 0.01747644160654315 0.04802748704882736 7.387524626203589e-06 5.131501058394072 0.2908319216850328 S(ph)FDHLISDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SFDHLISDTK 10 0 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 S(1)FDHLISDTK;S(1)FDHLISDTK;S(1)FDHLISDTK;S(1)FDHLISDTK;S(1)FDHLISDTK 145.09 7.7232e-05 29314600.0 207252.0 196166.0 165783.0 179114.0 212618.0 172261.0 163503.0 160504.0 141446.0 141621.0 True False 242335.67018641156 215640.06406407076 169735.89545552837 169078.82327542317 170957.02919108397 163227.32991184064 148014.81218078974 156290.94006804517 143514.3801604584 167295.76622878067 1.4485463419021145 1.2889750226504728 1.0145857201395687 1.0106581121975564 1.0218849708204596 0.975681175868035 0.8847493006988366 0.9342193385474791 0.8578482492151014 1.0 17.352041409842784 -4.272522444060623 0.6903639417551265 0.9268241103213911 2.2697479600029578 0.9189399697560885 0.0497065735053054 1.43463885868018 0.3143335593066949 0.021076878269119984 1.7685949969044124 5.339216801307688e-05 4.272522444060623 1.3429238496815668 S(ph)FDHLISDTK ddPTM_PC-9_Lapatinib_30min_R1 3 SFDHLISDTK 10 0 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 S(1)FDHLISDTK;S(1)FDHLISDTK;S(1)FDHLISDTK 167.2 0.0010726 19815600.0 192861.0 180105.0 172973.0 145546.0 170611.0 166934.0 158090.0 165475.0 171401.0 144301.0 True False 190110.7667736239 179687.9779381178 158751.82763508926 156249.93836722267 160575.9964141319 159794.6219621604 166275.12665968935 173163.5725961868 152096.0144474536 169243.2355810035 1.1232990560655687 1.061714385932519 0.938009883172596 0.923227081016411 0.9487882683339313 0.9441713957641704 0.9824624664547166 1.0231639214514245 0.8986829749816331 1.0 17.368738646855903 -5.085354649435422 3.338504770246386 0.9571861555885254 1.1159259302964781 0.7140269228276481 0.03512727477486513 0.12821288512091905 2.636547690751727 0.009308857580944144 0.03436554260241398 8.215714720456721e-06 5.085354649435422 0.15873977470795275 S(ph)FDYNYR ddPTM_PC-9_AZD4547_30min_R2 6 SFDYNYR 7 0 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 1 S(0.999)FDY(0.001)NYR;S(0.952)FDY(0.002)NY(0.046)R;S(0.997)FDYNY(0.003)R;S(1)FDYNYR;S(1)FDYNYR;S(0.999)FDY(0.001)NYR 119.68 0.0063844999999999996 760364600.0 176446.0 227190.0 243839.0 230918.0 238078.0 282729.0 253256.0 308452.0 262513.0 221065.0 True False 232552.15769520614 300624.7245574048 240605.53553842797 177683.42274753575 205024.9792254178 265049.91093535826 275795.2933781186 260787.83092182435 276388.9012490885 213325.58163694938 1.090127850165564 1.4092296022378905 1.1278794305499904 0.8329213092217339 0.9610895123414779 1.2424666038714312 1.2928374143495083 1.2224873778412997 1.295620052354828 1.0 17.702697455998063 -6.804079189396585 24.976929230721215 1.229722623531879 1.0907649906961319 0.1329538571557315 0.1572926979743707 298.7589587424336 175000.60550596984 0.060362252491263334 0.05323487110937161 1.5700764899749746e-07 6.804079189396585 -0.13895763283574714 S(ph)FDYNYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SFDYNYR 7 0 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 1 S(0.974)FDY(0.023)NY(0.003)R;S(0.999)FDYNY(0.001)R;S(0.991)FDY(0.002)NY(0.007)R;S(0.987)FDYNY(0.013)R;S(0.971)FDY(0.01)NY(0.019)R 107.79 0.0098558 694392000.0 183901.0 280667.0 266405.0 208537.0 247005.0 184044.0 238069.0 150156.0 181263.0 142804.0 True False 215031.8070896845 308529.7648964165 272757.10554658854 196853.3479760756 198606.1433902292 174392.40864905485 215517.3808497 146214.5641034332 183913.6284590945 168693.23476415765 1.274691349598641 1.8289397635166458 1.6168823007509332 1.1669308982739428 1.1773213292630937 1.033784246848221 1.27756979200147 0.8667482386466128 1.0902252761719566 1.0 17.364042591702436 -5.818069851795748 4.234038635194576 1.083907358480274 1.602287786629638 0.6542968244741872 0.16232523930105355 0.11953992263725564 4.346425850710889 0.04520862657881645 0.07154707855345546 1.5203029849852705e-06 5.818069851795748 0.5183804281493638 S(ph)FDYNYR ddPTM_PC-9_Lapatinib_30min_R1 5 SFDYNYR 7 0 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 1 S(0.95)FDY(0.05)NY(0.001)R;S(0.998)FDY(0.002)NYR;S(0.999)FDYNYR;S(1)FDYNYR;S(1)FDYNYR 119.68 0.0063844999999999996 566238700.0 217144.0 374123.0 255208.0 287631.0 352626.0 300486.0 355714.0 347695.0 265887.0 291128.0 True False 214047.48674066726 373256.7411795482 234225.78337136869 308784.3432488883 331885.2319693897 287634.9142470782 374131.1303980311 363850.179023002 235940.00614576435 341449.08689632424 0.6268796577735746 1.0931548963048827 0.6859757204226694 0.9043349509458373 0.9719903924363446 0.8423947384413832 1.0957157150390338 1.065605951183813 0.6909961549184166 1.0 18.381310950293035 -5.990033356154916 24.86702073699666 0.9490977687231924 0.8251246869295069 0.1362017912007779 0.15706425037440455 437.2236670605394 1090871.874167988 0.04247397647377758 0.06291832923015109 1.023214400886604e-06 5.990033356154916 -0.12397308179368549 S(ph)FDYNYRR ddPTM_PC-9_AZD4547_30min_R2 3 SFDYNYRR 8 1 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 1 S(0.756)FDY(0.004)NY(0.24)RR;S(0.998)FDYNY(0.002)RR;S(0.993)FDYNY(0.007)RR 83.883 0.006612699999999999 56669400.0 102452.0 44153.8 115323.0 217991.0 175862.0 100286.0 78780.0 112655.0 82129.0 110711.0 True False 135029.60486601738 58425.65237538073 113793.74166929032 167736.54287737687 151446.59689908524 94015.10056649032 85791.2673829177 95246.75830436547 86470.17127032341 106835.0415878057 1.2639074488967097 0.546877237159699 1.0651349967020456 1.5700517394334272 1.4175741839779614 0.8800024708112375 0.8030255439401638 0.8915310640477822 0.8093802369071501 1.0 16.70502539892678 -6.9034540446887 12.619453535605308 0.8633238995469026 1.1539769262265345 0.24783722798648222 0.25635398197144676 0.9338547810494388 116.27205634899585 0.1001796100481268 0.08835549322534288 1.2489525967847587e-07 6.9034540446887 0.2906530266796319 S(ph)FDYNYRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SFDYNYRR 8 1 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 1 S(0.946)FDYNY(0.054)RR;S(0.999)FDYNY(0.001)RR;S(0.617)FDYNY(0.383)RR 80.24 0.008975299999999999 76879800.0 175758.0 42937.0 135531.0 241766.0 247267.0 335935.0 228218.0 265657.0 297461.0 228227.0 True False 205510.35802126632 47199.501599252624 138762.57304417974 228220.63483594763 198816.8063710111 318317.97722023126 206599.538884764 258683.78523685798 301810.80438407674 269602.7484560616 0.7622710050181826 0.17507055053982487 0.5146927241611357 0.8465070780728402 0.7374435442872097 1.1806926266262046 0.7663109521987477 0.9594998074695699 1.1194648649261238 1.0 18.040475678537142 -5.915298909804659 1.770811660286275 0.9681525091303591 0.4381446400797245 0.5737932477543355 0.1837979614586953 0.2409802104480719 1.5358292515765637 0.057733921070524885 0.10277940801379837 1.2153492300650827e-06 5.915298909804659 -0.5300078690506347 S(ph)FDYNYRR ddPTM_PC-9_Lapatinib_30min_R1 4 SFDYNYRR 8 1 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 1 S(0.743)FDYNY(0.256)RR;S(0.583)FDYNY(0.416)RR;S(0.825)FDYNY(0.175)RR;S(0.539)FDYNY(0.461)RR 64.10300000000001 0.025407 154100200.0 860821.0 227219.0 263559.0 178115.0 167863.0 181667.0 117228.8 90369.7 220295.0 123239.2 True False 848545.5346847617 226692.88836579386 241890.19638716112 191214.17127422217 157989.62837135576 173897.52589646092 123298.33365907618 94568.60617280942 195483.05729080812 144540.9315140879 5.870624506125152 1.5683646562337181 1.67350655522505 1.322906731478932 1.0930442104972673 1.2031022913361518 0.8530340324191056 0.6542686917967743 1.3524408293422068 1.0 17.14111857152531 -4.742202917689206 3.598150731410589 1.1467062674343507 6.6489956357681 0.9648190140733871 0.26904202027079926 0.06276134506463873 1.278590498877112 0.07730969545243402 0.9881601757386501 1.810493968370276e-05 4.742202917689206 5.502289368333749 up S(ph)FEDLTDHPVTR ddPTM_PC-9_AZD4547_30min_R2 2 SFEDLTDHPVTR 12 0 P78536 P78536 ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 1 S(1)FEDLTDHPVTR;S(1)FEDLTDHPVTR 198.81 4.5017000000000005e-06 9486900.0 23361.4 32359.0 34910.0 26090.0 32702.0 24747.0 27359.0 31640.0 29488.0 23437.0 True False 30789.83925269365 42818.413935265955 34447.07059021123 20075.35358648183 28161.89177760906 23199.566177920562 29793.89799859416 26750.765014869423 31046.675479054873 22616.47776366759 1.361389672363405 1.8932397158699892 1.5230961668818734 0.8876427972675759 1.2451935297745584 1.0257815748475954 1.3173535821946947 1.1827997840514048 1.3727458273334692 1.0 14.465086644484591 -5.589465217692627 7.286316259469318 1.1623506861647699 1.647250663972518 0.5541510622836896 0.18400505531389313 0.14424095465106532 13.127878608477863 0.04734379846335333 0.082556298996107 2.573562870821817e-06 5.589465217692627 0.4848999778077481 S(ph)FEDLTDHPVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFEDLTDHPVTR 12 0 P78536 P78536 ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 1 S(1)FEDLTDHPVTR;S(0.999)FEDLT(0.001)DHPVTR 88.10799999999999 0.0046554 7768100.0 16743.5 19726.5 16854.3 18126.9 19699.6 14637.5 13776.5 13443.8 11641.900000000001 9912.7 True False 19577.843850800924 21684.816552103235 17256.170432288694 17111.308561202713 15839.604794761852 13869.88373215393 12471.490186777322 13090.914494883538 11812.14076318904 11709.79404110998 1.671920426787039 1.8518529425858044 1.473652770638566 1.4612817698696876 1.352680050490487 1.1844686322799913 1.0650477833336118 1.1179457511314725 1.0087402666280676 1.0 13.515428080624927 -6.076234216798662 0.5783053591048014 1.003262462170175 1.8617002880784215 0.9315902937231588 0.07280447697906962 0.2640801892646792 0.16858092842554634 0.049523733881326124 0.12732004794838375 8.390073843552923e-07 6.076234216798662 0.8584378259082466 S(ph)FEDLTDHPVTR ddPTM_PC-9_Lapatinib_30min_R1 2 SFEDLTDHPVTR 12 0 P78536 P78536 ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 1 S(1)FEDLTDHPVTR;S(1)FEDLTDHPVTR 209.22 2.2944e-08 9596200.0 35047.0 44027.0 24418.0 16625.199999999997 18690.9 20106.7 14126.099999999999 16657.800000000003 30891.0 23895.0 True False 34547.223353167356 43925.0581865108 22410.44629620577 17847.87266804139 17591.538009723256 19246.78331200697 14857.480338461864 17431.782200288675 27411.730283348963 28025.218911913882 1.2327191256472536 1.5673404130962094 0.7996528543325241 0.6368504283281095 0.6277038571943095 0.6867665645182495 0.5301468076006984 0.6220034268092086 0.9781094081550914 1.0 14.774438021871822 -5.345036940272172 5.247934560832841 0.6991714887970334 1.397170758386564 0.7205229831449296 0.16507217288832812 0.09395763855352124 4.33795270475352 0.04188342639240045 0.09059760992945792 4.518175119922842e-06 5.345036940272172 0.6979992695895306 S(ph)FEEEGEHLGSR ddPTM_PC-9_AZD4547_30min_R2 2 SFEEEGEHLGSR 12 0 Q9BXW6-4;Q9BXW6 Q9BXW6-4 OSBPL1A Oxysterol-binding protein-related protein 1 1 S(1)FEEEGEHLGSR;S(1)FEEEGEHLGSR 127.03 0.00013959 25413000.0 22993.4 27214.0 41892.0 60701.0 49690.0 38116.0 27114.0 48506.0 39845.0 45929.0 True False 30304.822907569156 36010.39330122461 41336.48470825344 46707.32227110129 42791.40121183395 35732.60049450922 29527.093473222045 41010.51225699296 41951.12535482029 44321.039689699595 0.683757039991373 0.8124898141681813 0.9326605376962811 1.053840852969798 0.9654873060610729 0.8062220729630951 0.6662094048322669 0.9253057361495963 0.9465284580083962 1.0 15.43570410429351 -8.090669460683694 0.01822153900234695 1.8012701237580395 1.9570367088694576e-05 0.1337799609551229 0.11601934260237613 900.3972153673245 16.096023707790657 798.398788500139 788.5053099323131 8.115785111214591e-09 8.090669460683694 -1.8012505533909509 S(ph)FEEEGEHLGSR ddPTM_PC-9_Lapatinib_30min_R1 1 SFEEEGEHLGSR 12 0 Q9BXW6-4;Q9BXW6 Q9BXW6-4 OSBPL1A Oxysterol-binding protein-related protein 1 1 S(1)FEEEGEHLGSR 119.77 0.0002966 6677500.0 15929.0 8185.1 11286.0 13584.0 13764.0 16921.0 13251.0 15533.0 13961.0 13161.0 True False 15701.849538979151 8166.147903841046 10358.108645219854 14583.012674895603 12954.42858106517 16197.32827477756 13937.071942359044 16254.71988600438 12388.5651641525 15435.861314069823 1.0172318356259704 0.5290373978935392 0.6710418313863972 0.9447488791314258 0.8392423537296995 1.0493310314995936 0.9029021224526921 1.0530491013927525 0.8025833422628833 1.0 13.91399836647838 -5.7685710606348195 24.650766520683884 0.9425040007233323 0.7180970496981119 0.31308045833421194 0.13645201228206408 140.02418813659165 483997.62359908404 0.03655206646163038 0.055550321601297796 1.703840508740718e-06 5.7685710606348195 -0.22440695102522035 S(ph)FEEKVENLK ddPTM_PC-9_AZD4547_30min_R2 3 SFEEKVENLK 10 1 H0YC42;P55327-2;P55327;P55327-3;P55327-4;P55327-7;P55327-5;P55327-6;E5RK35 H0YC42 TPD52 Tumor protein D52 1 S(1)FEEKVENLK;S(1)FEEKVENLK;S(1)FEEKVENLK 121.04 0.0031641 37267000.0 50683.0 45233.0 48098.0 54219.0 72276.0 59024.0 44714.0 51276.0 59387.0 54451.0 True False 66799.13972811023 59853.682670474525 47460.18909332509 41719.64722519962 62241.72497457266 55333.21994931037 48693.45937750423 43352.47240526061 62526.07557903658 52544.68706359449 1.2712824732834296 1.1391005640215157 0.9032347844394684 0.7939841220237281 1.1845483997124564 1.0530697400926747 0.9267056689969598 0.8250591035548732 1.1899599954484776 1.0 15.681257276286788 -5.022155993500945 3.8168338082228663 0.9796843339015675 1.2558574823949376 0.34819315050603794 0.12648586424005334 0.23376326951205345 7.3629324784895 0.03311727776969969 0.12837660709105575 9.502634088414716e-06 5.022155993500945 0.27617314849337005 S(ph)FEEKVENLK ddPTM_PC-9_Lapatinib_30min_R1 1 SFEEKVENLK 10 1 H0YC42;P55327-2;P55327;P55327-3;P55327-4;P55327-7;P55327-5;P55327-6;E5RK35 H0YC42 TPD52 Tumor protein D52 1 S(1)FEEKVENLK 110.15 0.0085961 6309400.0 16823.0 15397.0 18576.0 13704.0 17304.0 15602.0 11574.0 12481.0 17734.0 27266.0 True False 16583.10093503964 15361.349192488859 17048.752985433628 14711.837875203877 16286.21274097294 14934.738830038375 12173.245087983061 13060.912824130615 15736.610172701116 31978.891770338723 0.5185639656975515 0.480359022533011 0.5331251973292834 0.4600483963252754 0.5092800856869855 0.46701864896677703 0.3806650078872987 0.4084229346635758 0.4920936687148503 1.0 14.964832322584703 -8.586351666436025 21.09990431583489 1.0000000001446234 0.4688582108434868 0.9266632008870528 0.04458538445107319 3305.213496614633 1098729.1548220643 0.04746142032994004 0.012254486044433764 2.592079596659339e-09 8.586351666436025 -0.5311417893011366 S(ph)FELPPYTPPPILS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 1 SFELPPYTPPPILSPVR 17 0 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 2 S(0.99)FELPPY(0.002)T(0.01)PPPILS(0.999)PVR 116.85 0.0028905999999999997 0.0 6440.8 7062.2 6499.9 4807.6 10014.0 10463.0 14846.0 11869.0 11886.0 11361.0 True False 8488.840423037549 9344.918041151928 6413.707079040787 3699.2820966795725 8623.728954222284 9808.746955977804 16167.265239487137 10034.918772486897 12514.269694250064 10963.254848019269 0.7742992880048964 0.8523853701020436 0.5850185157557978 0.33742553173868084 0.7866029818489838 0.8946929622592829 1.474677498937104 0.915322950309771 1.1414739388741855 1.0 13.42038855886734 -6.859106686182548 2.966748797497636 1.1297746591272644 0.6479130983954933 0.566875663099268 0.19071772260473582 0.19447952990574607 3.445271530927747 0.07437118536525315 0.06540756016162552 1.3832265420806128e-07 6.859106686182548 -0.4818615607317711 S(ph)FEMTEFNQALEEIK ddPTM_PC-9_Lapatinib_30min_R1 1 SFEMTEFNQALEEIK 15 0 Q9BVS4;Q9BVS4-2;H0Y919 Q9BVS4 RIOK2 Serine/threonine-protein kinase RIO2 1 S(0.996)FEMT(0.004)EFNQALEEIK 98.676 0.001946 873950.0 5453.5 7104.4 5970.8 7187.8 5723.4 4928.1 8178.5 5945.6 8248.8 6737.8 True False 5375.732089950581 7087.950198293033 5479.90387195452 7716.414789797901 5386.760864637344 4717.336650962194 8601.94271229216 6221.854281479929 7319.733280285157 7902.419752445844 0.6802640530815591 0.8969341569206409 0.6934463169029281 0.9764622775713258 0.6816596730349727 0.5969483776791471 1.0885200965982362 0.7873353322637955 0.926264803640639 1.0 12.948078764575316 -7.263954671669589 24.999527993157564 0.9328079922865385 0.7648021387424855 0.3619478202763098 0.12631347743563445 299.05965939661985 2972332.4425671683 0.050648335417047 0.03593739192779057 5.4455948682318396e-08 7.263954671669589 -0.16800585354405306 S(ph)FENVSVESVDSSSEK ddPTM_PC-9_AZD4547_30min_R2 3 SFENVSVESVDSSSEK 16 0 Q52LW3;F8VWZ8;Q52LW3-2 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 S(1)FENVSVESVDSSSEK;S(1)FENVSVESVDSSSEK;S(0.962)FENVS(0.038)VESVDSSSEK 190.96 1.8423e-08 10925600.0 37434.9 41819.9 37307.4 42354.2 46043.2 50969.0 53090.0 55743.0 45796.0 46591.0 True False 49338.419505708625 55337.364842282754 36812.67949977788 32590.09355586691 39650.89644348385 47781.90037266869 57814.90715104219 47129.200196708836 48216.68306561303 44959.86327119669 1.0973881127729548 1.230817018025372 0.8187898454611567 0.7248708333315949 0.8819176385014942 1.062767920010111 1.2859226640059873 1.0482505231928034 1.0724383829810888 1.0 15.45635002769133 -6.936097114638934 6.510428376129232 1.115099123974654 0.9476611125541413 0.18849425659988017 0.14898544468346994 0.36557093501628424 28.84189858508673 0.05912626664739508 0.05196409293926916 1.1585182654505058e-07 6.936097114638934 -0.16743801142051262 S(ph)FENVSVESVDSSSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SFENVSVESVDSSSEK 16 0 Q52LW3;F8VWZ8;Q52LW3-2 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 S(0.999)FENVS(0.001)VESVDSSSEK;S(1)FENVSVESVDSSSEK;S(1)FENVSVESVDSSSEK 164.97 2.8137e-12 10437800.0 39438.0 36369.8 33548.5 38002.4 37892.4 36355.6 34079.0 36806.4 27675.6 28642.0 True False 46114.074463994155 39980.35338436542 34348.42347339477 35873.24873344314 30467.656232869394 34449.04833562394 30850.790409406167 35840.27099960436 28080.30329290879 33834.56787005276 1.3629278388038786 1.181642205034702 1.0151872961793262 1.0602543786349001 0.9004890013635007 1.01816132151979 0.9118127510271069 1.059279702854632 0.8299294201349291 1.0 15.04621034233328 -4.279107134545654 0.8016581876837021 0.9568896964795189 2.010512752135137 0.7873637513972835 0.06642130141584918 2.0696920135858856 0.5815037125392014 0.022416677499562415 2.3444890611923457 5.258875210846958e-05 4.279107134545654 1.0536230556556183 S(ph)FENVSVESVDSSSEK ddPTM_PC-9_Lapatinib_30min_R1 2 SFENVSVESVDSSSEK 16 0 Q52LW3;F8VWZ8;Q52LW3-2 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 S(0.999)FENVS(0.001)VESVDSSSEK;S(1)FENVSVESVDSSSEK 207.16 4.7548e-17 8321700.0 34163.0 37268.0 37992.0 50063.0 36376.0 38334.0 32116.0 40128.0 36407.0 63755.0 True False 33675.8293552731 37181.70823573911 34868.444413361016 53744.80002527227 34236.43519796765 36694.54418091856 33778.80933520514 41992.49337446625 32306.46027729389 74774.96680180235 0.4503623444532427 0.49724807413545913 0.4663117337889685 0.7187539135621097 0.45785958405992133 0.49073300531420744 0.45173954305775693 0.5615849149859345 0.432049142367726 1.0 16.19026774437404 -10.960421825921763 3.567034991376251 1.0048497089595083 0.5065928686422506 0.7761275665492032 0.08006267798990678 85231970.2656814 119710093.46978782 4154696.2515594126 0.020484277893219098 1.095413714792887e-11 10.960421825921763 -0.4982568403172577 S(ph)FEVEEVETPNSTPPR ddPTM_PC-9_AZD4547_30min_R2 5 SFEVEEVETPNSTPPR 16 0 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 SEPT9 Septin-9 1 S(1)FEVEEVETPNSTPPR;S(1)FEVEEVETPNSTPPR;S(1)FEVEEVETPNSTPPR;S(0.998)FEVEEVET(0.002)PNSTPPR;S(1)FEVEEVETPNSTPPR 293.77 1.4316999999999996e-111 154990000.0 21041.8 12646.9 23600.600000000002 35196.700000000004 39514.8 22391.6 18632.0 35085.0 21751.9 22665.15 True False 27732.654703370925 16734.7631013911 23287.6406236419 27082.644598594274 34028.85209509712 20991.44971226919 20290.21190503331 29663.419423094 22901.661026616028 21871.649997234745 1.2679726818450914 0.7651349168218627 1.0647409146811593 1.2382533828960485 1.5558429336332387 0.959756109617846 0.9276946141511327 1.3562497309002466 1.0470934305144564 1.0 14.416774440952167 -5.5307176193675955 18.544763785456393 1.167585904127087 0.9911506165440787 0.06205330528207764 0.21503244671922545 17.272211391642177 40860.402021879214 0.05877015008555162 0.10252365247178448 2.9463367352844053e-06 5.5307176193675955 -0.17643528758300842 S(ph)FEVEEVETPNSTPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SFEVEEVETPNSTPPR 16 0 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 SEPT9 Septin-9 1 S(1)FEVEEVETPNSTPPR;S(1)FEVEEVETPNSTPPR;S(1)FEVEEVETPNSTPPR;S(1)FEVEEVETPNSTPPR;S(1)FEVEEVETPNSTPPR;S(1)FEVEEVETPNSTPPR 289.87 5.896899999999999e-97 178160300.0 37902.6 38939.0 42848.2 43679.8 48911.9 46752.2 37484.1 43030.8 33546.9 29285.1 True False 44318.76156952648 42804.60658111413 43869.863590703426 41232.56241782229 39327.964312012 44300.43232945566 33933.33468661705 41901.28709490133 34037.459948000454 34594.25680927593 1.281101710433134 1.2373327404344387 1.26812562653291 1.1918903951353683 1.1368350685731974 1.2805718756639732 0.9808950333489556 1.2112209065773636 0.9839049335748071 1.0 15.078244927223171 -7.25394045139129 0.38921378147952596 0.9861299862936675 1.2913165667321436 0.5687103760652534 0.07761075105930053 0.9348762563407305 0.3393561730493276 0.08270237191749501 0.10074342907578403 5.5726215310548925e-08 7.25394045139129 0.305186580438476 S(ph)FEVEEVETPNSTPPR ddPTM_PC-9_Lapatinib_30min_R1 5 SFEVEEVETPNSTPPR 16 0 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 SEPT9 Septin-9 1 S(1)FEVEEVETPNSTPPR;S(1)FEVEEVETPNSTPPR;S(0.996)FEVEEVET(0.002)PNS(0.001)T(0.001)PPR;S(1)FEVEEVETPNSTPPR;S(1)FEVEEVETPNSTPPR 265.56 5.811899999999999e-69 161772800.0 35026.5 20929.5 36285.3 34352.8 29094.6 28003.899999999998 26153.3 30214.5 32439.1 51067.7 True False 34527.01568692658 20881.039028654657 33302.06269930853 36879.2195095814 27383.312830184444 26806.238477279312 27507.38990492028 31618.375973455175 28785.466959133235 59894.68390156703 0.5764621071157076 0.34862925502656084 0.5560103256248632 0.6157344376370694 0.45719104011279393 0.4475562225411124 0.45926262755016567 0.5278995382197508 0.4806013670001207 1.0 15.870140338336482 -10.879190887679137 2.8811594940075733 1.0070585039752313 0.49471541214249565 0.8125284088373301 0.07253669463367016 7041343.267762218 8435057.444419751 418200.65952608106 0.018831629577180743 1.3207150059582099e-11 10.879190887679137 -0.5123430918327356 S(ph)FEVEEVETPNSTPPRR ddPTM_PC-9_AZD4547_30min_R2 3 SFEVEEVETPNSTPPRR 17 1 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 SEPT9 Septin-9 1 S(1)FEVEEVETPNSTPPRR;S(1)FEVEEVETPNSTPPRR;S(1)FEVEEVETPNSTPPRR 137.61 2.8207e-05 40200600.0 74809.0 80374.0 99002.0 113849.0 125090.0 98883.0 82913.0 110238.0 85848.0 88566.0 True False 98596.70587613563 106353.3237007653 97689.16879324224 87602.87199951593 107723.41271057182 92699.8303782811 90292.09637623573 93203.25011723062 90385.75001783439 85465.33129739219 1.1536456289281842 1.2444031057539522 1.1430268544015232 1.025010617400941 1.260434038870435 1.0846483477109 1.056476292849646 1.0905386862997457 1.057572101409409 1.0 16.383051694186186 -6.28500730831618 0.1782822781715059 0.9642588846607624 1.3006690151271518 0.4174080221023747 0.06368842219664338 9.316065268830556 0.5842478625032496 0.25947696878064613 0.815699621180592 5.187913086250438e-07 6.28500730831618 0.33641013046638946 S(ph)FEVEEVETPNSTPPRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SFEVEEVETPNSTPPRR 17 1 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 SEPT9 Septin-9 1 S(1)FEVEEVETPNSTPPRR;S(1)FEVEEVETPNSTPPRR;S(0.961)FEVEEVET(0.035)PNS(0.002)T(0.002)PPRR;S(1)FEVEEVETPNSTPPRR 210.98 3.5249000000000004e-18 68092000.0 86680.0 99151.0 116960.0 127781.0 128973.0 122926.0 99423.0 92627.0 88811.0 88998.0 True False 101353.21199196231 108994.05601386887 119748.76997326998 120621.84484159149 103701.66649042741 116479.54416114454 90004.93367981438 90195.63939641889 90109.69286109481 105132.63289221974 0.9640509250431116 1.0367290632358441 1.1390256923940492 1.1473302011303288 0.9863889416404197 1.1079294882737072 0.8561084337351844 0.8579223873227448 0.8571048815401949 1.0 16.68185102198973 -7.264640787421668 24.99842049632955 0.880944116587638 1.0660834945292885 0.5953022059631214 0.06869181831056756 189.89232434440524 1482775.6790935218 0.02827865707709235 0.019976211113226727 5.4369984924012424e-08 7.264640787421668 0.18513937794165047 S(ph)FEVEEVETPNSTPPRR ddPTM_PC-9_Lapatinib_30min_R1 4 SFEVEEVETPNSTPPRR 17 1 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 SEPT9 Septin-9 1 S(0.882)FEVEEVET(0.113)PNS(0.003)T(0.001)PPRR;S(0.536)FEVEEVET(0.333)PNS(0.103)T(0.027)PPRR;S(1)FEVEEVETPNSTPPRR;S(0.991)FEVEEVET(0.007)PNS(0.002)TPPRR 123.02 7.3922e-05 46324900.0 42507.0 28761.399999999998 67417.2 44321.5 45079.6 46896.9 29172.0 35421.1 66306.7 63433.0 True False 41900.8423851709 28694.804745395144 61874.41805391768 47581.05096218977 42428.1065579036 44891.22890901341 30682.38342030774 37066.893617083006 58838.541205494636 74397.30953084047 0.5632037320892825 0.38569680713386645 0.8316754791820585 0.6395533825381904 0.5702908724181156 0.6033985528791779 0.41241254037000813 0.49822895277842527 0.7908692071869058 1.0 16.182962828884126 -8.506381576197748 3.6266056814010197 0.9985289682695436 0.5663196456086752 0.5868657936938881 0.11793594149475899 0.1440517559296365 4.826229445264519 0.118507790307132 0.031229188453665128 3.1161504947983095e-09 8.506381576197748 -0.4322093226608684 S(ph)FGHFPGPEFLDVEK ddPTM_PC-9_AZD4547_30min_R2 1 SFGHFPGPEFLDVEK 15 0 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 S(1)FGHFPGPEFLDVEK 92.307 0.0068544 0.0 9189.0 8873.3 12352.0 14209.0 14579.0 13791.0 12869.0 13022.0 12868.0 13635.0 True False 12110.910856926468 11741.420698161104 12188.204409346568 10933.334576861636 12554.957501858064 12928.64658987766 14014.316069443628 11009.749115791079 13548.176209457342 13157.642800171 0.9204468490943585 0.892365059340911 0.9263212715569515 0.8309493381838535 0.9541950402920877 0.9825959547791978 1.0651084151077195 0.8367569543420037 1.0296811074154764 1.0 13.68361343206439 -6.490775742259119 13.132031052355158 0.9767312573018158 0.8946206530967604 0.33066895154982 0.060426726968909134 2.884057918341138 1178.3985860918492 0.018330713905074538 0.020614633960952772 3.2301616578919225e-07 6.490775742259119 -0.08211060420505534 S(ph)FGNPFEGSR ddPTM_PC-9_AZD4547_30min_R2 2 SFGNPFEGSR 10 0 F5GZ00;Q96RR4-6;Q96RR4-5;Q96RR4-2;Q96RR4-3;Q96RR4-4;Q96RR4-7;Q96RR4 F5GZ00 CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 1 S(1)FGNPFEGSR;S(1)FGNPFEGSR 107.53 0.0021589 15687200.0 20885.9 10273.7 26919.7 29884.0 28415.2 28325.6 18158.2 42346.0 32554.2 24882.8 True False 27527.181746292372 13594.472611846528 26562.72718898048 22994.705503197485 24470.239962054817 26554.39575420481 19774.244622905528 35802.398714275034 34274.94855128349 24011.660745734862 1.14640890681341 0.5661612812125577 1.106242815532814 0.9576474424944549 1.0190981882167984 1.1058958409997361 0.8235267369591661 1.4910421687777067 1.4274293192057392 1.0 14.55144756932257 -7.7604212029849675 24.999920637057297 1.3444268325576052 0.9588457291226788 0.3799843054610855 0.20042186276691493 24.52029000987513 602115.0847108196 0.09608152158347574 0.051390313064906566 1.7361162297263206e-08 7.7604212029849675 -0.38558110343492635 S(ph)FGNPFEGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SFGNPFEGSR 10 0 F5GZ00;Q96RR4-6;Q96RR4-5;Q96RR4-2;Q96RR4-3;Q96RR4-4;Q96RR4-7;Q96RR4 F5GZ00 CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 1 S(1)FGNPFEGSR;S(1)FGNPFEGSR;S(1)FGNPFEGSR 94.54700000000001 0.0062606 14979700.0 30730.9 41222.0 36421.0 41162.0 35079.0 29758.9 34708.5 33161.4 33259.0 27848.6 True False 35933.034407058134 45314.24773329278 37289.41476741166 38855.826589004566 28205.5217667085 28198.290896450602 31420.659612220847 32290.948387407643 33745.349955153746 32897.330730603695 1.0922781152463044 1.3774445137926612 1.133508826985835 1.1811239917060445 0.857380253665064 0.8571604525414679 0.9551127375507967 0.9815674302525722 1.0257777517420632 1.0 15.005682908861086 -6.189703914160987 6.190591980361944 0.941555136410622 1.2073135644943847 0.6670766390149541 0.08637368380735717 0.1387000358507223 9.538407844379442 0.026000277512894677 0.03365295427993566 6.460945621792889e-07 6.189703914160987 0.2657584280837626 S(ph)FGNPFEGSR ddPTM_PC-9_Lapatinib_30min_R1 3 SFGNPFEGSR 10 0 F5GZ00;Q96RR4-6;Q96RR4-5;Q96RR4-2;Q96RR4-3;Q96RR4-4;Q96RR4-7;Q96RR4 F5GZ00 CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 1 S(1)FGNPFEGSR;S(1)FGNPFEGSR;S(1)FGNPFEGSR 82.705 0.014549000000000001 15584300.0 42022.6 41400.2 54253.0 40882.3 51438.3 39374.4 36741.7 43128.7 46908.4 47370.2 True False 41423.35001799898 41304.340380520705 49792.52776263625 43888.92072135488 48412.800325588774 37690.448698209395 38644.00544748119 45132.61685106014 41625.08202464943 55558.07595317606 0.7455864751851787 0.7434443988904818 0.8962248405542522 0.7899647345301183 0.8713908733338916 0.6783972996108546 0.6955605424502115 0.8123502492976463 0.7492174865762224 1.0 15.761709017369911 -10.629770643301045 4.280420578925156 1.0000331508495404 0.7774630482212244 0.5079954591143474 0.06617661806324111 19446567.34785657 16097528.315267479 5305.464467152953 0.01671335065790615 2.3454671607375956e-11 10.629770643301045 -0.222570102628316 S(ph)FGNPFEPQAR ddPTM_PC-9_AZD4547_30min_R2 1 SFGNPFEPQAR 11 0 J3KPJ3;Q8N5S9;Q8N5S9-2 J3KPJ3 CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 1 S(1)FGNPFEPQAR 110.15 0.0019722000000000003 14083000.0 6678.7 5864.6 4857.0 12722.0 5405.2 13498.0 10583.0 6253.4 5004.1 6225.9 True False 8802.387674410147 7760.217261496362 4792.59300649258 9789.13945294066 4654.7812805434705 12653.967926195963 11524.86649801242 5287.080718836429 5268.606509927372 6007.933136016471 1.4651274365291165 1.2916617222277766 0.7977107764002653 1.6293689079621314 0.7747724841741164 2.106209846167847 1.918274760569976 0.8800165712799528 0.8769416021531649 1.0 12.552653041443326 S(ph)FGNPFEPQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFGNPFEPQAR 11 0 J3KPJ3;Q8N5S9;Q8N5S9-2 J3KPJ3 CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 1 S(1)FGNPFEPQAR;S(1)FGNPFEPQAR 143.94 0.00016380000000000002 22927000.0 72255.0 81948.0 59063.0 69795.0 68087.0 54297.0 49671.0 77263.0 51145.0 46632.0 True False 84486.34439869906 90083.25586453547 60471.28591767486 65884.61242844288 54745.84111661911 51449.569735594334 44965.803293101744 75234.92811691547 51892.89886816616 55086.01246129112 1.533716829804436 1.6353199630820416 1.0977611777611962 1.1960316146451866 0.9938247237461407 0.9339860962299258 0.8162835043596443 1.3657719038890856 0.9420340400320543 1.0 15.749398413145299 -5.305806635357867 4.789561833356051 1.0441007971868206 1.5877411791862135 0.6883118887680105 0.1458331925493172 0.10550417467071645 5.6948236025078565 0.039213328822318885 0.08920603101309199 4.945308221593403e-06 5.305806635357867 0.5436403819993929 S(ph)FGNPFEPQAR ddPTM_PC-9_Lapatinib_30min_R1 1 SFGNPFEPQAR 11 0 J3KPJ3;Q8N5S9;Q8N5S9-2 J3KPJ3 CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 1 S(1)FGNPFEPQAR 96.135 0.0059301 11501000.0 27193.0 28195.0 30316.0 27261.0 25667.0 29437.0 23223.0 23213.0 31027.0 23972.0 True False 26805.22283341453 28129.716209795628 27823.53550314415 29265.86488003011 24157.31752326354 28178.048130998584 24425.37330898831 24291.560723222818 27532.412531205468 28115.528259317813 0.9533956675536042 1.0005046304073306 0.9896145377927625 1.040914636570311 0.8592162060927141 1.002223677645468 0.8687502892958612 0.863990905636721 0.9792600116656498 1.0 14.779079533308423 -6.25241663191973 24.998981646021228 0.9227644062766618 0.9959576824789248 0.26275478434664257 0.05456615894439191 847.2523533682985 2347449.450477319 0.01566353281161706 0.019928583759296476 5.592208664789857e-07 6.25241663191973 0.07319327620226301 S(ph)FGTRPLSSGFSPEEAQQQDEEFEK ddPTM_PC-9_Lapatinib_30min_R1 1 SFGTRPLSSGFSPEEAQQQDEEFEK 25 1 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 S(0.275)FGT(0.213)RPLS(0.171)S(0.171)GFS(0.171)PEEAQQQDEEFEK 49.871 0.012514 6153200.0 9492.7 6967.5 9246.4 9045.0 6773.0 9217.9 7685.4 8511.8 8749.6 5657.0 True False 9357.332357252024 6951.367181831923 8486.19668413617 9710.199473235481 6374.625456230336 8823.67190497441 8083.312407048993 8907.289301853609 7764.127910627368 6634.804912521317 1.410340240689324 1.0477123703687479 1.27904238271134 1.4635244896063526 0.9607856659357132 1.3299067600800478 1.2183195306608077 1.3425096019091112 1.1702119373509796 1.0 12.695838330381768 -8.538773127672355 21.040870262358833 0.9999999944950994 1.2490136402731928 0.2229491376029583 0.14586561910166387 475.36845591728087 629291.5484205 0.13342366266717337 0.034449841568153436 2.8921903473314283e-09 8.538773127672355 0.24901364577809348 S(ph)FILDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFILDK 6 0 Q9BVP2-2;Q9BVP2 Q9BVP2-2 GNL3 Guanine nucleotide-binding protein-like 3 1 S(1)FILDK 87.476 0.039704 4399700.0 24324.0 29934.0 29964.0 29206.0 34980.0 25691.0 27346.0 24651.0 20710.0 19346.0 True False 28441.57277910125 32905.64969308586 30678.455399102808 27569.682507129568 28125.920106031055 24343.718733579295 24755.58891210486 24003.937369893472 21012.844570529294 22853.276657148253 1.2445293165522957 1.4398657219595397 1.3424094872411623 1.2063776639445738 1.230717175833671 1.0652178722023586 1.0832402409289341 1.0503499226832012 0.9194674744357373 1.0 14.480113410395719 -6.622606207874397 0.7442718203951497 0.9802622732183742 1.3655677345493977 0.8363630229013121 0.0621723445025837 0.2542735765948302 0.313230766112969 0.041241463739837114 0.04742165723273638 2.3844805930645093e-07 6.622606207874397 0.3853054613310235 S(ph)FLESNYFTKPNLK ddPTM_PC-9_AZD4547_30min_R2 1 SFLESNYFTKPNLK 14 1 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 S(1)FLESNYFTKPNLK 74.33800000000001 0.0088588 7109500.0 23205.0 24379.0 34957.0 41845.0 32067.0 42883.0 29673.0 33615.0 24965.0 29973.0 True False 30583.707306015767 32259.034992671215 34493.44733950197 32198.28174880536 27615.050566711194 40201.51923092767 32313.83951578217 28420.574145854487 26284.598932942365 28923.654393071152 1.0573943005397786 1.1153167077117017 1.1925687836930141 1.1132162385579696 0.9547566220859891 1.3899183929039824 1.1172115071158906 0.9826066153197716 0.9087578829333202 1.0 14.819962222353267 -7.7761724623813295 4.5268813810852455 0.9541895727646198 1.138898782762842 0.35491962290204526 0.10587274812007524 0.21666259713692365 10.711171020777781 0.05866209401477981 0.02884776655080653 1.6742778726676608e-08 7.7761724623813295 0.18470920999822227 S(ph)FLNYYADLETSAR ddPTM_PC-9_AZD4547_30min_R2 2 SFLNYYADLETSAR 14 0 Q92870;Q92870-4;H0YAJ5;G5E9Y1;Q92870-2 Q92870 APBB2 Amyloid beta A4 precursor protein-binding family B member 2 1 S(1)FLNYYADLETSAR;S(1)FLNYYADLETSAR 100.41 0.007215300000000001 2103400.0 5878.700000000001 5019.6 8459.9 9662.1 6652.6 8997.900000000001 7710.5 7361.9 5256.4 8026.3 True False 7748.00431544386 6642.08753637198 8347.716198399532 7434.652122956916 5729.00132223479 8435.259890585176 8396.719562782268 6224.287514632345 5534.242572846713 7745.30168001558 1.0003489386908264 0.8575634379109968 1.0777780573658353 0.9598918712410903 0.7396743934476759 1.089080869806508 1.0841049076819662 0.8036210559353996 0.7145289882156767 1.0 12.919105717839118 -7.790475766485521 24.996024836366523 0.8193061025403247 0.9672814136232184 0.19347692204548528 0.12229390167055038 330.09810561622777 284161.03782983636 0.0669184250365715 0.032154919966425576 1.6200343888617758e-08 7.790475766485521 0.14797531108289375 S(ph)FLNYYADLETSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFLNYYADLETSAR 14 0 Q92870;Q92870-4;H0YAJ5;G5E9Y1;Q92870-2 Q92870 APBB2 Amyloid beta A4 precursor protein-binding family B member 2 1 S(1)FLNYYADLETSAR;S(1)FLNYYADLETSAR 110.32 0.0026773000000000005 1338300.0 5452.6 4796.4 7406.9 7590.400000000001 6616.2 6327.8 9332.8 8411.4 7374.0 6397.299999999999 True False 6375.617486241054 5272.554893696699 7583.508586824677 7165.134496408829 5319.803104789099 5995.959028544746 8448.729620379292 8190.609662614986 7481.830799762582 7557.079849001063 0.8436615218620218 0.6976973909298648 1.003497215637745 0.948135343224666 0.7039495692892938 0.7934227437516523 1.1179886661507346 1.0838326213659983 0.9900425758703042 1.0 12.883613151222667 -7.257740094866107 24.980455795727057 1.054952020736994 0.8329259442121191 0.5517482322478104 0.09539699579704808 257.1223456947437 1736297.60866339 0.03964468524078245 0.02953030035806933 5.52407930941859e-08 7.257740094866107 -0.22202607652487494 S(ph)FLNYYADLETSAR ddPTM_PC-9_Lapatinib_30min_R1 2 SFLNYYADLETSAR 14 0 Q92870;Q92870-4;H0YAJ5;G5E9Y1;Q92870-2 Q92870 APBB2 Amyloid beta A4 precursor protein-binding family B member 2 1 S(1)FLNYYADLETSAR;S(1)FLNYYADLETSAR 148.41 0.0002141 2898900.0 5265.6 7470.200000000001 7194.0 5602.8 7513.9 7851.1 7092.900000000001 6565.6 9262.0 6401.0 True False 5190.511578407227 7452.903210867717 6602.537089643062 6014.848602392895 7071.947174895785 7515.326754807996 7460.135656173762 6870.661744901201 8218.816026816161 7507.404321203631 0.6913856449355392 0.9927403523236408 0.8794700281420975 0.8011888457112644 0.9419963108849809 1.001055282660345 0.9937037272794319 0.9151847231000949 1.0947613416268582 1.0 12.874098468003668 -6.482987204641387 4.351918501575016 0.9938666836386014 0.855124124706573 0.4580859660397527 0.08115086569198407 0.21985847062132055 9.266504374890383 0.02555783193874054 0.02801182084391449 3.288613197776593e-07 6.482987204641387 -0.13874255893202847 S(ph)FLYCNQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFLYCNQAR 9 0 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4;A8MXE8;Q7Z5J4-4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 S(0.992)FLY(0.008)CNQAR;S(1)FLYCNQAR 86.189 0.011855 6945700.0 11323.8 15228.400000000001 10053.0 11671.0 10725.1 13031.2 14941.8 10452.3 9027.099999999999 9362.3 True False 13240.695684755241 16740.174911010516 10292.701646214804 11017.111707892522 8623.593645774547 12347.820931883482 13526.40453473592 10177.938200127282 9159.104259904634 11059.610878073978 1.1972117130273843 1.5136314555332533 0.9306567617691147 0.9961572635194867 0.7797375279152985 1.1164787864610517 1.223045248504397 0.9202799549037807 0.8281579126859556 1.0 13.433013006157445 -5.271871518233028 24.984781911470375 0.9792585304345295 1.3554215881284088 0.5403461597512714 0.14054128760438173 475.2718859143619 1138268.5311157568 0.03792810751231056 0.08030133244023459 5.34722528419915e-06 5.271871518233028 0.37616305769387937 S(ph)FLYCNQAR ddPTM_PC-9_Lapatinib_30min_R1 1 SFLYCNQAR 9 0 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4;A8MXE8;Q7Z5J4-4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 S(1)FLYCNQAR 69.65 0.039793 5524500.0 11965.0 5733.8 14538.0 5753.9 9295.1 13555.0 9351.0 4985.1 5804.8 4786.3 True False 11794.37690588773 5720.52373838362 13342.741758302865 6177.061000447722 8748.38049286972 12975.28424824831 9835.149025205601 5216.725945002284 5151.002296746111 5613.605577656137 2.1010341290868295 1.0190462545414751 2.376857720715372 1.1003731763831626 1.5584245048656327 2.311399343746896 1.7520199609948541 0.9293004064564929 0.9175924858790706 1.0 12.454711985642978 -7.761750754233836 24.958648777475947 0.94258461895967 1.731675687324827 0.42115274706197847 0.42774713614231147 7.872595549086995 630829.6974593203 0.21080371833573466 0.11117877923537368 1.7308094023363133e-08 7.761750754233836 0.7890910683651569 S(ph)FNDFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFNDFR 6 0 P42356 P42356 PI4KA Phosphatidylinositol 4-kinase alpha 1 S(1)FNDFR 96.03399999999999 0.034587 4340300.0 25639.0 27490.0 34232.0 32513.0 41775.0 27543.0 41110.0 30648.0 29819.0 31538.0 True False 29979.176306667345 30219.02552491918 35048.22070558294 30691.402018568195 33589.4886343467 26098.596593319617 37215.76318937434 29843.5224742402 30255.046462994367 37255.58974532936 0.8046893502853693 0.81112728939441 0.9407506617171951 0.8238066348799619 0.9015959447684688 0.7005283441148998 0.9989309911283846 0.8010481830577278 0.8120941493561343 1.0 15.1851692801004 -10.980315981845001 2.9357267959871605 1.0039099910313116 0.8459265496113414 0.25740927521224943 0.07949916802932702 47907976.9034128 54136366.16499525 1540045.9267035867 0.018647908554563553 1.046366960497206e-11 10.980315981845001 -0.15798344141997023 S(ph)FNDFR ddPTM_PC-9_Lapatinib_30min_R1 1 SFNDFR 6 0 P42356 P42356 PI4KA Phosphatidylinositol 4-kinase alpha 1 S(1)FNDFR 96.03399999999999 0.034587 4966400.0 67303.0 65352.0 70901.0 61298.0 66088.0 62290.0 52271.0 50679.0 82329.0 51689.0 True False 66343.24687814142 65200.681459214924 65071.793465774645 65806.0594041336 62200.83377400714 59626.00190508211 54977.336616032706 53033.73135278542 73056.24105719577 60623.37477873683 1.0943509351018643 1.0755039899574108 1.0733779454422268 1.0854898732429947 1.02602063974544 0.983548047641773 0.9068669769159003 0.87480664919015 1.2050837044924738 1.0 15.887586545776406 -6.490101603266705 2.7610445445171807 0.9810638723759428 1.08118716533347 0.1948618186240243 0.0822797058691982 0.4166605107783751 6.356647640681583 0.028244229841193465 0.030791585953071816 3.2351796099433117e-07 6.490101603266705 0.10012329295752709 S(ph)FNGTDNHIR ddPTM_PC-9_AZD4547_30min_R2 4 SFNGTDNHIR 10 0 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 S(0.996)FNGT(0.004)DNHIR;S(0.999)FNGT(0.001)DNHIR;S(1)FNGTDNHIR;S(1)FNGTDNHIR 135.81 6.4688e-05 114553000.0 52055.1 61143.1 80339.0 106712.0 81235.5 86775.0 76333.1 95700.0 70769.5 72117.3 True False 68607.53898665721 80906.41135651166 79273.65236742994 82111.19708396502 69957.35305179992 81348.94553234962 83126.59802319128 80911.76396722531 74510.23129120232 69592.49527779759 0.9858468030610391 1.1625737952569666 1.1391120845859508 1.1798858017117448 1.0052427747064665 1.1689327305713486 1.1944764689262628 1.162650708876636 1.070664746159399 1.0 16.086644116524795 -4.752761378265146 24.698915522790116 1.1281536850616352 0.9858464877815319 0.2547847361222315 0.0678735396927979 379.4563544140369 1079895.4068471133 0.016338609441876626 0.18841515717041693 1.767008431227942e-05 4.752761378265146 -0.14230719728010321 S(ph)FNGTDNHIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SFNGTDNHIR 10 0 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 S(0.999)FNGT(0.001)DNHIR;S(0.92)FNGT(0.08)DNHIR;S(1)FNGTDNHIR;S(0.961)FNGT(0.039)DNHIR 113.35 0.00074821 84470000.0 67483.0 64253.0 69248.0 72743.0 86518.0 71885.0 76822.0 61255.0 61105.0 59796.0 True False 78906.53904999557 70631.61320671631 70899.1349445023 68667.44554598788 69565.41897465981 68115.22405368996 69544.86401688433 59647.12115503734 61998.5450256974 70636.54145512437 1.1170781782984824 0.9999302308931534 1.0037175303882162 0.9721235515135256 0.984836142053401 0.9643057637096203 0.9845451459577251 0.844423012881107 0.8777120701058854 1.0 16.108127086243485 -1.5228787452803378 0.361205553461511 0.9205508106423983 3.181817290075318 0.5524491916946516 0.04686912896747824 49.859806050382474 0.6951495956630709 0.039952139174828 77.6022417890575 0.02999999999999998 1.5228787452803378 2.26126647943292 S(ph)FNGTDNHIR ddPTM_PC-9_Lapatinib_30min_R1 4 SFNGTDNHIR 10 0 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 S(1)FNGTDNHIR;S(1)FNGTDNHIR;S(1)FNGTDNHIR;S(0.998)FNGT(0.002)DNHIR 136.33 6.5252e-05 107970600.0 103411.6 85738.7 86142.6 76771.4 82802.0 76822.0 64996.8 66844.6 81254.1 57780.3 True False 101936.93162063492 85540.17730791989 79060.287948052 82417.42485788264 77931.74915499549 73536.50214082871 68362.0162722151 69950.44414420951 72102.4076143947 67767.54786758969 1.5042145514813143 1.262258706409976 1.1666393493022218 1.216178354555741 1.149986263443758 1.0851285675041824 1.0087721693248652 1.032211528162196 1.0639666017615814 1.0 16.04830694879898 -1.5228787452803376 0.3607456181437273 1.0182426112332315 6.748301921021443 0.9155920032176552 0.04216643754638396 18.2476231944584 0.254522267822601 0.03726997278142141 71.84537148462998 0.029999999999999995 1.5228787452803376 5.730059309788212 S(ph)FPLFDNSK ddPTM_PC-9_AZD4547_30min_R2 4 SFPLFDNSK 9 0 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 S(0.991)FPLFDNS(0.009)K;S(1)FPLFDNSK;S(0.999)FPLFDNS(0.001)K;S(1)FPLFDNSK 114.86 0.0020136 51482400.0 97279.4 108236.2 139153.0 172302.0 171923.0 169974.0 133409.9 169624.0 150997.0 146702.0 True False 128212.22566278109 143221.434975748 137307.7402990449 132580.43593936347 148054.45905699595 159345.4989100038 145283.12265077812 143412.50837175117 158978.393153515 141566.0076326137 0.905670985619035 1.01169367824111 0.9699202696693991 0.9365273355976159 1.0458333997891698 1.1255915284658637 1.0262571155344786 1.0130433906416958 1.122998351172615 1.0 17.111115366219856 -6.331150589824659 5.993618313190292 1.0590726778362296 0.9610792039304794 0.5235494451664322 0.04648265131464381 0.18804786349147673 12.542052111341134 0.014256661280080008 0.016255695140485017 4.664975961448918e-07 6.331150589824659 -0.0979934739057502 S(ph)FPLFDNSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SFPLFDNSK 9 0 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 S(0.999)FPLFDNS(0.001)K;S(1)FPLFDNSK;S(1)FPLFDNSK;S(1)FPLFDNSK 131.12 0.0012439999999999999 43006700.0 141340.0 159655.0 170982.0 170478.0 218476.0 172325.0 191011.0 153867.0 150405.0 131249.0 True False 165266.07040775212 175504.49327686316 175058.85933284636 160926.67035713344 175667.19614308857 163287.97363917532 172917.05528011653 149828.15428556263 152604.38858669563 155043.40473348764 1.0659342181748186 1.131970067211483 1.1290958143867156 1.0379459263924116 1.1330194692579942 1.0531758762641965 1.1152815921280423 0.9663626424039786 0.9842688171677824 1.0 17.24231263205028 -7.762841420508345 24.99998088067003 0.9814867722841157 1.0955567765336545 0.7075716244412762 0.03288645689651029 19.04894071798527 339637.7101469926 0.01618237571388259 0.008438197141368068 1.7264681842910994e-08 7.762841420508345 0.11407000424953873 S(ph)FPLFDNSK ddPTM_PC-9_Lapatinib_30min_R1 4 SFPLFDNSK 9 0 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 S(1)FPLFDNSK;S(1)FPLFDNSK;S(0.999)FPLFDNS(0.001)K;S(1)FPLFDNSK 144.7 0.00053429 40284600.0 132793.0 112659.0 140947.0 116957.0 122591.0 124450.0 102210.0 103566.0 124164.0 96716.0 True False 130899.34746874627 112398.14500724805 129358.88173115364 125558.40793711468 115380.43840317933 119127.56360711921 107501.93368262904 108378.05444627111 110179.3428151156 113433.23173403055 1.1539770618161433 0.9908749251788093 1.1403966875815046 1.106892627651783 1.017166104142342 1.0501998557745431 0.9477111075764044 0.9554347768243753 0.9713145004407138 1.0 16.791483832833364 -6.825844272820586 1.4191042887521248 0.9656515516710638 1.091076674645763 0.5685537583356998 0.0474267018581426 0.29809738408001296 1.2490095335969282 0.021941712211940627 0.01876792228354547 1.4933297844369664e-07 6.825844272820586 0.1254251229746992 S(ph)FPPLAAS(ph)RPARPGGWR ddPTM_PC-9_Lapatinib_30min_R1 1 SFPPLAASRPARPGGWR 17 2 Q6XYB7-2 Q6XYB7-2 2 S(1)FPPLAAS(1)RPARPGGWR 95.073 0.028211 0.0 10972.0 14125.0 12309.0 17083.0 14743.0 14054.0 15985.0 12993.0 15447.0 14715.0 True False 10815.537267981621 14092.294430337413 11297.001534114052 18339.340807217424 13875.845725853218 13452.943181474126 16812.6250847943 13596.702213278499 13707.196195878783 17258.46814349498 0.626680026179391 0.8165437577175148 0.6545773031641913 1.0626285400729405 0.8040021634876828 0.7794981031699951 0.9741667073234002 0.78782787094597 0.794230176276987 1.0 14.07501679656575 -4.490365604846322 0.9133209291328093 0.8660598765901475 0.40869917050442117 0.2905752165432447 0.11374672448710971 4.616157436347343 2.117687056805378 0.03778848472538431 2.3823727286495027 3.233213586841354e-05 4.490365604846322 -0.4573607060857263 S(ph)FQDYTGQK ddPTM_PC-9_AZD4547_30min_R2 2 SFQDYTGQK 9 0 A0A087WXU5;A0A087WYV3;A0A0D9SEW3;A0A087WXF8;Q9NP64-2;Q9NP64-3;Q9NP64 A0A087WXU5 ZCCHC17 Nucleolar protein of 40 kDa 1 S(1)FQDYTGQK;S(1)FQDYTGQK 83.617 0.014057 13109900.0 41758.0 46918.0 48538.0 75705.0 64575.0 58956.0 40715.0 67495.0 48092.0 48962.0 True False 55036.17537964256 62083.32596850355 47894.35440583418 58252.38188059045 55609.87589563651 55269.47200006001 44338.55612459378 57065.19863080312 50634.044938236104 47247.855282872915 1.1648396535703256 1.3139924679503583 1.0136831422101737 1.2329106058218608 1.1769820145845813 1.1697773723095297 0.9384247360888412 1.207783893875262 1.0716686426312914 1.0 15.527961222259053 -7.038992814012452 24.69036352035592 1.0692583802391435 1.1807285131400616 0.2877196217117636 0.09474291185950642 674.7784207335832 427269.7992631491 0.03495209474004169 0.027079030823887795 9.141283668310134e-08 7.038992814012452 0.111470132900918 S(ph)FQDYTGQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFQDYTGQK 9 0 A0A087WXU5;A0A087WYV3;A0A0D9SEW3;A0A087WXF8;Q9NP64-2;Q9NP64-3;Q9NP64 A0A087WXU5 ZCCHC17 Nucleolar protein of 40 kDa 1 S(1)FQDYTGQK 130.44 8.3067e-06 0.0 18143.0 20764.0 20403.0 14824.0 20817.0 20474.0 14772.0 16067.0 14763.0 13355.0 True False 21214.25155941595 22825.31269550462 20889.48489880839 13993.459340056446 16738.058286084866 19400.30739758289 13372.689219981457 15645.258274393676 14978.880946147956 15776.155781878171 1.3447034786373264 1.446823485460489 1.3241175599193704 0.8870005807200838 1.0609719197443281 1.2297233664406209 0.8476519505051072 0.9917028261324058 0.9494633010250804 1.0 13.94545808236127 -5.663198930661086 5.59952351485239 1.0019475425882836 1.3916339552528123 0.7463554962574588 0.10091610599084241 0.1027121455534524 4.819189208408206 0.028404199062398414 0.04971993629451688 2.171706190611603e-06 5.663198930661086 0.38968641266452875 S(ph)FQDYTGQK ddPTM_PC-9_Lapatinib_30min_R1 1 SFQDYTGQK 9 0 A0A087WXU5;A0A087WYV3;A0A0D9SEW3;A0A087WXF8;Q9NP64-2;Q9NP64-3;Q9NP64 A0A087WXU5 ZCCHC17 Nucleolar protein of 40 kDa 1 S(0.85)FQDY(0.147)T(0.003)GQK 93.766 0.006003100000000001 6755500.0 26259.0 24129.0 29790.0 27971.0 24234.0 26095.0 28101.0 23941.0 29970.0 21770.0 True False 25884.541844689178 24073.13078298133 27340.781192725462 30028.0806485207 22808.603765877142 24978.97768041607 29555.932280751 25053.386260917465 26594.463001908916 25532.915493298387 1.0137714923892291 0.9428273394512975 1.0708052983570007 1.176053735673161 0.8933019721881627 0.97830495256103 1.1575619826301673 0.981219174421864 1.041575648064521 1.0 14.640070661813562 S(ph)FQGDDSDLLLK ddPTM_PC-9_AZD4547_30min_R2 3 SFQGDDSDLLLK 12 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 S(0.999)FQGDDS(0.001)DLLLK;S(0.989)FQGDDS(0.011)DLLLK;S(0.998)FQGDDS(0.002)DLLLK 79.875 0.014907 6798200.0 35938.1 43844.0 48351.0 62080.0 60100.0 63532.0 53101.0 57104.0 51495.0 50903.0 True False 47365.66824108274 58015.71558384991 47709.83414801783 47768.41512643894 51756.15240151379 59559.3339966723 57826.88612973238 48279.88891937753 54216.920570873925 49120.90146366735 0.9642670804019572 1.1810800261221117 0.9712735867298113 0.9724661743386612 1.0536482609097804 1.2125049056912323 1.177235848827092 0.9828787233289706 1.1037444133832903 1.0 15.584049416748353 S(ph)FQGDDSDLLLK ddPTM_PC-9_Lapatinib_30min_R1 4 SFQGDDSDLLLK 12 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 S(1)FQGDDSDLLLK;S(1)FQGDDSDLLLK;S(1)FQGDDSDLLLK;S(1)FQGDDSDLLLK 123.02 0.0017920000000000002 1700800.0 68706.0 60465.8 69086.2 59230.3 69052.0 70923.9 60973.4 60663.0 72247.0 64557.9 True False 67726.2398408628 60325.79515510768 63406.19931644399 63586.29384848861 64990.49712145539 67890.65012868603 64130.30430686249 63481.62444116942 64109.78206536239 75716.64699700536 0.8944696117293919 0.7967309376165799 0.8374142520990364 0.8397927849473246 0.85833828753703 0.8966410006424499 0.846977604665971 0.838410401924958 0.8467065646461864 1.0 16.20832290432722 -11.02230293636877 2.621269442933268 1.0073314680236398 0.8494338088697824 0.7283683169637785 0.02736061144139127 3815922.770930931 3758363.106349855 200778.51820729865 0.007087253049032101 9.499419430701589e-12 11.02230293636877 -0.15789765915385745 S(ph)FSADNFIGIQR ddPTM_PC-9_AZD4547_30min_R2 1 SFSADNFIGIQR 12 0 Q8N7R7-3;Q8N7R7-2;Q8N7R7 Q8N7R7-3 CCNYL1 Cyclin-Y-like protein 1 1 S(0.892)FS(0.108)ADNFIGIQR 170.26 0.00018969 14108000.0 18373.0 26105.0 25034.0 29163.0 23052.0 20021.0 21515.0 29552.0 19009.0 16911.0 True False 24215.2318178594 34542.93073890161 24702.03280307498 22439.920913858554 19851.627706484127 18769.0837050207 23429.793319922253 24985.41743740272 20013.77693235736 16318.951037307803 1.4838718348072375 2.11673720081216 1.5137022438882302 1.375083537082574 1.216476945184776 1.1501403283894591 1.4357413822958287 1.5310676145961803 1.2264131981646724 1.0 13.994260705124134 -5.554938871962506 3.502426543226112 1.2985734102472455 1.8074749025472319 0.5123414434860405 0.2022436164337795 0.17432130484951655 4.4766103695686414 0.054271301399953724 0.10776402806617713 2.786513349771156e-06 5.554938871962506 0.5089014922999864 S(ph)FSADNFIGIQR ddPTM_PC-9_Lapatinib_30min_R1 1 SFSADNFIGIQR 12 0 Q8N7R7-3;Q8N7R7-2;Q8N7R7 Q8N7R7-3 CCNYL1 Cyclin-Y-like protein 1 1 S(0.91)FS(0.09)ADNFIGIQR 153.7 0.00022913 10400000.0 86749.0 63026.0 28724.0 17498.0 25793.0 20499.0 13354.0 16891.0 30165.0 12570.0 True False 85511.94335218167 62880.06716930586 26362.423597846446 18784.86129161685 24275.906450989092 19622.30555550292 14045.404778376178 17675.81752362713 26767.500048467864 14742.707751527822 5.800287490832195 4.265164054601127 1.788167007184582 1.2741798595085174 1.6466382472021344 1.3309838251029167 0.9527018384340299 1.19895326025135 1.8156434014432583 1.0 13.847713904045863 -5.111050255393146 1.9526904179530373 1.3081128052272875 6.00850000078414 0.9721446549984843 0.25516870538886904 0.06378787892597963 0.39944641382311924 0.07359990571514491 0.4237466825181888 7.743721843445454e-06 5.111050255393146 4.700387195556852 S(ph)FSASQSTDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFSASQSTDR 10 0 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 S(0.678)FS(0.322)AS(0.001)QSTDR 86.463 0.01125 9486700.0 13040.0 25312.0 30287.0 29636.0 33957.0 31818.0 34582.0 23897.0 24130.0 23654.0 True False 15247.414448260166 27824.80807881972 31009.156944087146 27975.591001208377 27303.369612364106 30149.408067612214 31306.14260800156 23269.729070964433 24482.855600524974 27942.28295503903 0.5456753291344969 0.9957958024973 1.1097574594739779 1.0011920302368615 0.9771345332196736 1.0789887181417708 1.1203859991817848 0.8327783777870604 0.8761938185193922 1.0 14.77016227693826 -4.761729753661962 7.729496353936961 1.003446044561071 0.5391605543102838 0.7068249805197545 0.08758701519096748 0.05637110933225306 26.598791544725444 0.023417556001255006 0.13740547557987506 1.7308930986935036e-05 4.761729753661962 -0.46428549025078714 S(ph)FSEDTLMDGPAR ddPTM_PC-9_AZD4547_30min_R2 1 SFSEDTLMDGPAR 13 0 Q9BRG2;M0QZQ6 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 S(0.986)FS(0.014)EDTLMDGPAR 147.7 0.00011129 6641900.0 10829.0 8974.4 12242.0 24851.0 15843.0 13097.0 13354.0 15936.0 12231.0 14024.0 True False 14272.396742807343 11875.199296042845 12079.663081219303 19121.985894122645 13643.472920086238 12278.04251958724 14542.480129874131 13473.457372849543 12877.505689918602 13533.02402857339 1.0546347004684875 0.8774978357364738 0.892606342508113 1.4129869165789417 1.00816143467119 0.9072652567278086 1.0745920571166794 0.9955984223778751 0.9515615772741748 1.0 13.724196633021304 -7.989792615068445 22.421083175144698 0.9750471522278497 1.0304265140681137 0.025797257975025523 0.1442599457077855 291.4952154669615 640284.7842750447 0.082965762990208 0.039743830019825906 1.0237817533238122e-08 7.989792615068445 0.05537936184026404 S(ph)FSEDTLMDGPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFSEDTLMDGPAR 13 0 Q9BRG2;M0QZQ6 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 S(0.745)FS(0.244)EDT(0.011)LMDGPAR 103.11 0.0013920999999999998 33374000.0 35554.0 39820.0 38092.0 37034.0 49526.0 33822.0 34695.0 37705.0 33827.0 29471.0 True False 41572.58997649094 43773.066438788 39000.25774471447 34959.10504584798 39821.73582536575 32048.314779771867 31408.438429952384 36715.28370174979 34321.655880603306 34813.85900769239 1.1941390917710433 1.257346002036603 1.1202509246704615 1.0041720752107228 1.1438472194813805 0.9205619742611857 0.9021820425886269 1.0546168896024215 0.9858618624559741 1.0 15.087374120720677 -5.630925369298124 1.0018419681442805 0.9839666729936963 1.2531064790102315 0.6529666740360023 0.06564170906431602 0.44270054694384364 0.7837100489252802 0.025753310530472688 0.09592500163388001 2.3392391872688643e-06 5.630925369298124 0.2691398060165352 S(ph)FSEDTLMDGPAR ddPTM_PC-9_Lapatinib_30min_R1 2 SFSEDTLMDGPAR 13 0 Q9BRG2;M0QZQ6 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 S(0.827)FS(0.149)EDT(0.024)LMDGPAR;S(0.96)FS(0.034)EDT(0.006)LMDGPAR 87.831 0.0069042 5457600.0 42770.2 44610.7 47456.4 39333.6 38534.0 40020.0 33904.7 37593.0 43396.0 34817.2 True False 42160.28910490591 44507.40666502321 43554.71797900153 42226.324157043106 36267.50588075885 38308.43789117649 35660.119469028796 39339.708019993755 38508.28549986118 40835.30662899717 1.0324469824102624 1.0899246348114473 1.066594610754638 1.0340640892128914 0.8881408975390251 0.9381204906631863 0.8732668470697005 0.963374865221622 0.9430144813095742 1.0 15.317529440374091 -6.122355821831909 4.6818637858801635 0.9299957891495502 1.0635720495060048 0.732670380285795 0.036118864397351604 0.10931289697552087 3.6987536490540265 0.01051211686279471 0.013839554071751784 7.544738263834991e-07 6.122355821831909 0.13357626035645465 S(ph)FSEDVFQSVK ddPTM_PC-9_AZD4547_30min_R2 1 SFSEDVFQSVK 11 0 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 S(0.974)FS(0.026)EDVFQSVK 124.48 0.00050912 9259600.0 35023.0 23197.0 36820.0 45870.0 36938.0 38941.0 39926.0 45909.0 35238.0 32938.0 True False 46159.58547634515 30694.97660794105 36331.742742239396 35295.380184435446 31809.79629629148 36506.013114090754 43479.33665308931 38814.8189338698 37100.6087401972 31784.85064554693 1.452251136590196 0.965710896371364 1.14305217751053 1.1104466268549336 1.0007848283140524 1.1485349898664778 1.3679264105392543 1.2211735510957253 1.167241877394035 1.0 14.95605168888882 -7.014301125416306 24.793983302990238 1.2147614620819605 1.1192633236511136 0.013114606510930882 0.1486678317266733 1592.5195709888742 2760963.17105894 0.05311935140225353 0.042815039808419844 9.676067171505467e-08 7.014301125416306 -0.09549813843084687 S(ph)FSEDVFQSVK ddPTM_PC-9_Lapatinib_30min_R1 2 SFSEDVFQSVK 11 0 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 S(0.997)FS(0.003)EDVFQSVK;S(0.999)FS(0.001)EDVFQSVK 175.88 0.0019344999999999998 13295200.0 50590.0 45280.0 51322.0 43139.0 52301.0 54353.0 47654.0 49717.0 56479.0 49174.0 True False 49868.57732293024 45175.15694199489 47102.503268649045 46311.585967485364 49224.75800772225 52028.448893031404 50121.29094718722 52027.033320831804 50117.740269763526 57673.660379763685 0.8646681517101685 0.7832892284715428 0.8167073662135063 0.802993700461138 0.8535050087612273 0.902118030144779 0.8690499374784539 0.9020934856267048 0.8689883725040738 1.0 15.815624968515497 -9.365727151724313 0.18219576379338162 1.087093430872066 0.7744695942729465 0.7472329908974101 0.029306537642787397 4.892970564832114 0.35550462428198243 0.40330921585008844 0.14179732926745126 4.30797176561703e-10 9.365727151724313 -0.3126238365991194 S(ph)FSEDVISHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFSEDVISHK 10 0 E9PHM6;F6QMI7;F8W9J4;Q03001-8;Q03001-14;Q03001;H0YC82;A0A494C1D7;Q03001-10 E9PHM6 DST Dystonin 1 S(0.748)FS(0.252)EDVISHK 71.268 0.019049 1429300.0 12212.0 16525.0 19801.0 18476.0 28532.0 23738.0 20654.0 16849.0 18337.0 15966.0 True False 14279.250402005595 18165.49279007964 20273.130935710666 17440.849620000197 22941.35941867576 22493.137491639296 18697.503597989242 16406.731602991156 18605.143934804237 18860.509413213535 0.7570978115788144 0.9631496367406189 1.0748983758364161 0.9247284491574371 1.2163700839704366 1.1926049821263454 0.9913572952006221 0.8698986460830543 0.9864603085306705 1.0 14.203081022582174 -4.786580326087774 2.7870055068551087 1.0344273872822358 0.70697082818201 0.3951492974253631 0.10219779695137785 0.4858201241200595 5.214846911087526 0.028995685627866457 0.36856306571491154 1.6346307856958105e-05 4.786580326087774 -0.32745655910022586 S(ph)FSEDVISHK ddPTM_PC-9_Lapatinib_30min_R1 1 SFSEDVISHK 10 0 E9PHM6;F6QMI7;F8W9J4;Q03001-8;Q03001-14;Q03001;H0YC82;A0A494C1D7;Q03001-10 E9PHM6 DST Dystonin 1 S(0.9)FS(0.1)EDVISHK 92.792 0.004084 2982800.0 22133.0 19485.0 25619.0 23211.0 25407.0 25319.0 21861.0 21956.0 26385.0 21662.0 True False 21817.37936130491 19439.88367965484 23512.70471219983 24918.014369626162 23912.610212083873 24236.16539147171 22992.855613305506 22976.155914318704 23413.243453632535 25406.247837199342 0.8587407121708196 0.7651615383831426 0.9254693909492994 0.9807829369097818 0.941209830169077 0.9539450904665103 0.9050079240603096 0.9043506172791661 0.9215545563304831 1.0 14.632895703922378 -5.341691559720233 6.486173024726441 0.9392964003740337 0.8125427046485714 0.6772704229256541 0.03580999868473271 0.12242994342668059 8.118686003225074 0.00928785924500613 0.019645043958871677 4.553113119905771e-06 5.341691559720233 -0.12675369572546236 S(ph)FSEGGER ddPTM_PC-9_AZD4547_30min_R2 1 SFSEGGER 8 0 G3V2D5;G3V515;G3V2P5;Q07352 G3V2D5 ZFP36L1 Zinc finger protein 36, C3H1 type-like 1 1 S(0.977)FS(0.023)EGGER 70.399 0.038245 34927000.0 17027.0 18339.0 29574.0 22891.0 23594.0 23022.0 20811.0 25961.0 15249.0 21345.0 True False 22441.23181639862 24266.723111308816 29181.829436691693 17613.833612424496 20318.380362085143 21582.43070061369 22663.13868375096 21949.3239744319 16055.031008549488 20597.71804691235 1.0895008740913714 1.1781267738513617 1.4167506017039653 0.8551351937291353 0.9864384159356391 1.0478068809107208 1.1002742455321755 1.065619207158832 0.7794567811824271 1.0 14.330196894396765 -5.770663125627454 24.999999862347405 0.98768046542037 1.2231261738979444 0.48405207717705634 0.11866630411355039 174.17490773690935 472083.3607145515 0.03409444814586299 0.051366513518601435 1.695652577484372e-06 5.770663125627454 0.2354457084775744 S(ph)FSEGGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFSEGGER 8 0 G3V2D5;G3V515;G3V2P5;Q07352 G3V2D5 ZFP36L1 Zinc finger protein 36, C3H1 type-like 1 1 S(0.794)FS(0.206)EGGER 81.525 0.017759999999999998 28487000.0 56260.0 48772.0 52076.0 70938.0 58004.0 64530.0 95429.0 103340.0 76547.0 72113.0 True False 65783.70681434947 53613.76183708103 53317.689339329816 66963.57384409892 46638.532585197994 61145.9332014274 86389.2742738701 100627.43449778047 77666.35506230356 85186.51605380602 0.7722314500196108 0.6293691105199934 0.6258935311505518 0.7860818465894648 0.5474872637793977 0.7177888712200184 1.0141191150405118 1.1812601237761804 0.911721228430653 1.0 16.378337467725636 -7.249877259912575 4.286782297552135 1.0461785533066765 0.6706763182795581 0.7804289602571056 0.09027320602666973 0.08739141825984702 4.0438349492924015 0.03570532669975921 0.025557259702982126 5.62500276272319e-08 7.249877259912575 -0.37550223502711844 S(ph)FSEGGER ddPTM_PC-9_Lapatinib_30min_R1 1 SFSEGGER 8 0 G3V2D5;G3V515;G3V2P5;Q07352 G3V2D5 ZFP36L1 Zinc finger protein 36, C3H1 type-like 1 1 S(0.849)FS(0.151)EGGER 89.029 0.010532 24694000.0 19684.0 20866.0 20786.0 15317.0 22917.0 27822.0 28654.0 23890.0 26935.0 28068.0 True False 19403.302550396504 20817.686059003227 19077.05531628034 16443.46327601414 21569.067116555543 26632.11791624968 30137.563914901213 25000.016614732816 23901.296661875756 32919.516401740904 0.5894163909822924 0.6323812842494342 0.5795059405936922 0.49950500716178653 0.6552060745161764 0.8090069608325497 0.915492303930304 0.7594284287059188 0.7260524841917717 1.0 15.006655521811577 -6.684561205159302 3.3250747377050724 0.8341084720175505 0.5793524396552516 0.7253434958300937 0.07831381903731532 0.1370333651367974 3.0303843595628077 0.027745292691086176 0.027011596892020807 2.0674679929421928e-07 6.684561205159302 -0.2547560323622988 S(ph)FSELPSCDGNESWAYR ddPTM_PC-9_AZD4547_30min_R2 4 SFSELPSCDGNESWAYR 17 0 Q8NEV8-2;Q8NEV8 Q8NEV8-2 EXPH5 Exophilin-5 1 S(1)FSELPSCDGNESWAYR;S(0.967)FS(0.033)ELPSCDGNESWAYR;S(0.994)FS(0.006)ELPSCDGNESWAYR;S(0.978)FS(0.022)ELPSCDGNESWAYR 203.05 2.4996e-17 15943300.0 27380.2 25403.600000000002 41198.9 43396.299999999996 43237.399999999994 43220.9 38881.600000000006 52438.7 43775.9 42779.9 True False 36086.53405646078 33614.81690552621 40652.575667116944 33391.95350115144 37234.63334185049 40518.29029051144 42341.9870763602 44335.50383644862 46089.80470372888 41282.18872218812 0.8741429457461202 0.814269251365035 0.984748554411487 0.8088707148224464 0.9019539538570499 0.9814956896588648 1.025672048575333 1.073962045346191 1.1164573907138018 1.0 15.333231841951555 -7.001750243863967 1.6229906046533988 1.0675907044225224 0.8717488429337109 0.7172525290761189 0.052971015284831655 0.19597344142513523 1.043449166452408 0.025143857166392763 0.018866083057261784 9.95978024465831e-08 7.001750243863967 -0.19584186148881144 S(ph)FSELPSCDGNESWAYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFSELPSCDGNESWAYR 17 0 Q8NEV8-2;Q8NEV8 Q8NEV8-2 EXPH5 Exophilin-5 1 S(0.998)FS(0.002)ELPSCDGNESWAYR;S(0.964)FS(0.007)ELPS(0.02)CDGNES(0.009)WAYR 103.6 0.00084892 8436000.0 6136.7 8498.9 9348.2 7709.5 12490.099999999999 12828.5 12843.5 13024.7 12256.099999999999 10356.2 True False 7175.522104650159 9342.614624726644 9571.096541245923 7277.561709536235 10042.754565933057 12155.750876716438 11626.87070111237 12682.815425810382 12435.322276236797 12233.697080365902 0.5865375002758809 0.7636787606684154 0.7823552012422117 0.5948783643839061 0.8209092067557295 0.9936285651722927 0.9503971387171716 1.0367115797043298 1.0164811335891655 1.0 13.57857283848302 -6.610009623720364 3.1818740859884933 1.0001509331115814 0.694647566755399 0.850337477785562 0.06273271717745849 0.0944808725392275 1.920044291353014 0.021973328199993963 0.022177345005176912 2.454654521324924e-07 6.610009623720364 -0.30550336635618247 S(ph)FSELPSCDGNESWAYR ddPTM_PC-9_Lapatinib_30min_R1 3 SFSELPSCDGNESWAYR 17 0 Q8NEV8-2;Q8NEV8 Q8NEV8-2 EXPH5 Exophilin-5 1 S(0.999)FS(0.001)ELPSCDGNESWAYR;S(0.994)FS(0.006)ELPSCDGNESWAYR;S(0.939)FS(0.055)ELPS(0.006)CDGNESWAYR 170.47 1.3835e-05 11778100.0 18780.9 27193.5 23763.3 24138.399999999998 24189.2 26154.7 27867.9 29150.4 31123.5 23892.3 True False 18513.080922004763 27130.53512151365 21809.57320299069 25913.61845934186 22766.438813796958 25036.124450583553 29310.763503318067 30504.834002767144 27618.04368501543 28022.052220511392 0.6606611384605758 0.9681851603165176 0.7783003554260265 0.9247580532440013 0.8124472338657814 0.8934436440832045 1.0459891828287784 1.0886009976256636 0.9855824786736983 1.0 14.77427499627236 -7.147660254559882 3.5082048097449157 1.037937652521498 0.8398672623493463 0.5693553659611854 0.0821675352409929 0.17719435760148772 4.011834333077557 0.03132105440231162 0.023554186788175686 7.117701085359393e-08 7.147660254559882 -0.19807039017215178 S(ph)FSEPFGR ddPTM_PC-9_AZD4547_30min_R2 1 SFSEPFGR 8 0 A0A494C127;A0A494C1S3;A0A494C175;A0A0S2Z4A4;A0A494C1P6;P58340-2;P58340-5;P58340-4;P58340;P58340-3 A0A494C127 MLF1 Myeloid leukemia factor 1 1 S(0.769)FS(0.231)EPFGR 112.11 0.0037351999999999997 6918100.0 22894.0 18710.0 23019.0 48032.0 32756.0 33394.0 27350.0 47372.0 33658.0 31981.0 True False 30173.8157752176 24757.641606008387 22713.753019652602 36958.9644870025 28208.394809716923 31305.86790097704 29784.09701602945 40051.745900265305 35437.093165831146 30861.3549242588 0.9777216797276533 0.8022214729965551 0.7359933831614854 1.1975807471094093 0.9140361749815301 1.0144035470188908 0.9650936288807409 1.2977960947781437 1.1482675745378745 1.0 14.91351378233944 -6.512558832561411 0.6811867859020063 1.1368687966918887 0.8522522147223285 0.2937969713982165 0.13745704719449992 0.9190899900391113 0.9472752936547953 0.09754847719815209 0.1329409358218068 3.072141163395155e-07 6.512558832561411 -0.2846165819695602 S(ph)FSEPFGR ddPTM_PC-9_Lapatinib_30min_R1 3 SFSEPFGR 8 0 A0A494C127;A0A494C1S3;A0A494C175;A0A0S2Z4A4;A0A494C1P6;P58340-2;P58340-5;P58340-4;P58340;P58340-3 A0A494C127 MLF1 Myeloid leukemia factor 1 1 S(0.723)FS(0.277)EPFGR;S(0.883)FS(0.117)EPFGR;S(0.769)FS(0.231)EPFGR 112.11 0.0037351999999999997 20328700.0 91332.0 65146.0 69853.0 61376.0 89693.0 96630.0 100630.0 76452.0 106597.0 102055.0 True False 90029.58893176232 64995.15843955831 64109.955980377636 65889.7957843339 84417.43408322282 92497.3601555318 105840.12901362857 80004.23902174771 94590.92334382658 119695.07077026054 0.7521578654192257 0.5430061406982101 0.5356106610557801 0.5504804446859886 0.7052707646186311 0.7727750153811155 0.8842480173371151 0.6684004487979766 0.7902658207653498 1.0 16.869004215509143 -6.561502902272019 2.591289313198497 0.8080212837936199 0.5880860752536113 0.5396886307056155 0.09857014994901252 0.23151954782797687 3.151337530071119 0.034525982255119984 0.03605112877061626 2.7447140012393536e-07 6.561502902272019 -0.2199352085400086 S(ph)FSGLIK ddPTM_PC-9_Lapatinib_30min_R1 1 SFSGLIK 7 0 Q14CB8-4;Q14CB8-6;Q14CB8-7;Q14CB8-3;Q14CB8;Q14CB8-2 Q14CB8-4 ARHGAP19 Rho GTPase-activating protein 19 1 S(0.999)FS(0.001)GLIK 86.13600000000001 0.018816 5655100.0 22982.0 25158.0 32684.0 34164.0 41313.0 46173.0 43736.0 48004.0 50252.0 41990.0 True False 22654.27246561737 25099.748196702905 29996.8476838885 36676.53452776308 38883.0505644831 44198.288424520084 46000.436078108454 50234.44108721784 44592.09058298052 49247.915551841936 0.460004696884477 0.5096611280995453 0.6090988288085338 0.7447327286198477 0.7895369809825143 0.897465160286708 0.934058539588037 1.020031823160869 0.9054614816344794 1.0 15.587775042460372 -5.828744047893738 0.6127211386996941 0.9887256696426122 0.37184862301003613 0.9716386900024543 0.03216636854414528 0.18293495321001543 0.11690419989243543 0.019285313849474933 0.06833869628645325 1.4833920669256741e-06 5.828744047893738 -0.6168770466325761 down S(ph)FSGNPR ddPTM_PC-9_AZD4547_30min_R2 1 SFSGNPR 7 0 Q9NQS3-3 Q9NQS3-3 1 S(0.649)FS(0.351)GNPR 101.25 0.011258 214610000.0 83800.0 79995.0 101560.0 159380.0 125850.0 135380.0 101460.0 130250.0 104280.0 98415.0 True False 110446.65685171807 105851.81936251427 100213.24804187493 122637.40339645352 108377.8998291269 126914.66719872675 110489.7434459361 110122.85534724245 109792.02790816073 94969.52080519477 1.1629695076409896 1.1145872745808805 1.055214843585831 1.2913343392351342 1.1411861290890992 1.3363726185273601 1.1634231962965993 1.159559976859637 1.1560764651363302 1.0 16.535176953639535 -9.013694472676974 1.4092921363765594 1.000063415074196 1.1799185229513343 0.3241009725902634 0.07683786868195551 3.0136395796171156 7.3727729248918 0.07565867759265305 0.0221167906008163 9.689592819725617e-10 9.013694472676974 0.1798551078771382 S(ph)FSGNPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFSGNPR 7 0 Q9NQS3-3 Q9NQS3-3 1 S(0.624)FS(0.376)GNPR;S(0.917)FS(0.083)GNPR 98.58200000000001 0.012116 231243000.0 444361.0 399356.0 561510.0 567240.0 621730.0 514636.0 502055.0 502768.0 497965.0 372868.0 True False 519582.5407701948 439001.42442814127 574898.5279385325 535459.3818168918 499906.46962614986 487647.5821951001 454496.7158365691 489570.8727267302 505246.7960677763 440466.0167785351 1.1796200409972586 0.9966749027289199 1.3052051827816484 1.2156655937570755 1.1349490098744694 1.1071173793647915 1.0318542146807403 1.1114838695328564 1.147073274263092 1.0 18.748671189799673 -6.706612803669753 2.9141980606939373 1.0815537583493127 1.1708147543863243 0.2355003291128145 0.08084524721228822 0.44807914361255385 7.754977167099511 0.03020784139336154 0.0289807532332544 1.9651114961314792e-07 6.706612803669753 0.08926099603701165 S(ph)FSGNPR ddPTM_PC-9_Lapatinib_30min_R1 1 SFSGNPR 7 0 Q9NQS3-3 Q9NQS3-3 1 S(0.617)FS(0.383)GNPR 72.87899999999999 0.037712999999999997 182420000.0 83557.0 74290.0 83055.0 71580.0 81309.0 66115.0 73179.0 70577.0 78942.0 53606.0 True False 82365.46185752297 74117.98606936417 76226.53850157133 76844.23198388013 76526.56447964454 63287.41557159258 76967.85055240298 73856.26507400567 70050.72066388706 62871.72567449489 1.310055688370203 1.1788762798255996 1.2124136515071682 1.2222383139557031 1.217185684958684 1.006611714449351 1.2242045168425597 1.1747135024793325 1.1141847931224267 1.0 15.940123741645758 -8.832706342763997 0.02610819438711911 1.8915154837543244e-08 2.210168607366619 0.526603388849334 0.064530466568844 246.7693687922218 3.184092612774469 141.38452315970278 127.06500930648147 1.4699198585394003e-09 8.832706342763997 2.2101685884514644 S(ph)FSKEELMSSDLEETAGSTSIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFSKEELMSSDLEETAGSTSIPK 23 1 O00567 O00567 NOP56 Nucleolar protein 56 1 S(0.297)FS(0.297)KEELMS(0.189)S(0.189)DLEET(0.022)AGS(0.004)T(0.001)S(0.001)IPK 49.902 0.044164 0.0 11154.0 11463.0 14225.0 18538.0 15560.0 19531.0 20226.0 22662.0 14424.0 14918.0 True False 13042.151898458114 12600.970883672184 14564.17794861292 17499.3759610069 12511.129698394605 18506.759977639533 18310.046856440895 22067.146512373776 14634.923712472948 17622.51530917698 0.7400845832527876 0.715049506985543 0.8264528470024128 0.9930123852350433 0.7099514160659799 1.0501769839860533 1.039014382181066 1.2522132127689083 0.8304673569982242 1.0 14.105132238262241 -6.775713346131952 24.895257408165218 1.0504277955905588 0.8048981742878577 0.4834400622281876 0.12203003553823939 193.20172348146923 336961.359995416 0.042567125322996086 0.03771461598599175 1.6760487785012782e-07 6.775713346131952 -0.24552962130270106 S(ph)FSKEVEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFSKEVEER 9 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 S(0.981)FS(0.019)KEVEER;S(0.974)FS(0.026)KEVEER 63.693999999999996 0.026619999999999998 407621000.0 270207.0 181035.0 164295.0 301959.0 281020.0 230470.0 276677.0 258032.0 192238.0 179888.0 True False 315947.7082684835 199006.9583813661 168212.4158922572 285041.21619428694 225956.1483189498 218383.74748075244 250468.1515919856 251258.93340750327 195049.11707143468 212500.27040737512 1.4868108528181812 0.9365021418554359 0.79158683219454 1.3413687222507844 1.0633216978302145 1.0276869157017936 1.178672154683963 1.182393476139233 0.9178770299798416 1.0 17.69710515152306 -6.368715194497329 0.014431694155874478 3.6562579689142035e-07 2.1987154102801383 0.06096255311356946 0.19183765919447357 7034.844995650417 30.86868602495332 2228.0563308336705 2473.3819485242598 4.278433691072042e-07 6.368715194497329 2.1987150446543415 S(ph)FSKEVEER ddPTM_PC-9_Lapatinib_30min_R1 1 SFSKEVEER 9 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 S(0.992)FS(0.008)KEVEER 106.49 0.012383 188810000.0 233340.0 145460.0 185010.0 141110.0 130700.0 149790.0 123880.0 118890.0 151700.0 89468.0 True False 230012.52881068486 145123.19630703566 169799.19195925235 151487.7001291605 123012.48296608654 143383.83087754442 130293.9002505048 124414.06342928387 134613.94852818092 104932.42459138368 2.1920062335962824 1.383015753921235 1.618176580027248 1.4436691110404365 1.1723019214042583 1.366439700939857 1.2416934113347804 1.185658902991744 1.2828632241404863 1.0 16.679101020502785 -1.5228787452803376 0.5487816057539003 1.2154874431690887 39.29275809662269 0.774758726088457 0.14807571512696702 62.27969964769095 0.572642575275262 0.0703658293052381 2793.924782865958 0.029999999999999995 1.5228787452803376 38.0772706534536 up S(ph)FSLASSSNSPISQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFSLASSSNSPISQR 15 0 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 S(0.989)FS(0.011)LASSSNSPISQR;S(0.487)FS(0.2)LAS(0.311)S(0.002)SNSPISQR 229.23 1.2911999999999998e-24 25134700.0 37603.0 42630.0 20615.3 31899.0 26713.0 24484.6 18598.7 24384.5 15053.2 11467.1 True False 43968.44520689624 46862.02466814497 21106.846935960617 30111.80244795336 21478.779410875006 23200.584473325092 16836.89649307265 23744.432712513382 15273.32457214349 13545.994456486345 3.2458632216435355 3.4594746674878216 1.5581614922228055 2.222930368433354 1.5856184999832283 1.7127265589729928 1.2429428158381162 1.752874828702121 1.1275159325663264 1.0 13.725578690016434 -1.522878745280575 0.34139405346225665 1.1920325216274394 28.088609549972016 0.7845269657395523 0.3730202425319794 25.14015207239473 0.3559468386309553 0.3081684294731737 431.5979782410667 0.0299999999999836 1.522878745280575 26.896577028344577 up S(ph)FSLASSSNSPISQR ddPTM_PC-9_Lapatinib_30min_R1 3 SFSLASSSNSPISQR 15 0 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 S(0.843)FS(0.06)LAS(0.096)S(0.001)SNSPISQR;S(1)FSLASSSNSPISQR;S(1)FSLASSSNSPISQR 185.86 4.0444000000000004e-07 33622200.0 43637.8 37774.0 39188.2 35537.8 32915.8 32165.9 31643.0 28352.5 40154.1 29293.6 True False 43015.51696980756 37686.53662382763 35966.297466826545 38151.3683626255 30979.757358952706 30790.23943937519 33281.31970961189 29669.86065588999 35631.522416581596 34356.95972873155 1.2520175623640866 1.0969112785701953 1.046841680719181 1.110440756803077 0.9017025255888808 0.8961863821037217 0.968692223421034 0.8635764308061897 1.0370976564257568 1.0 15.068314756586231 -4.723829215936124 0.653343378529559 0.9390232206097096 1.4410145325792896 0.6672399375956664 0.06467307062387015 2.0846082912025934 0.6388483921047576 0.029955150225344663 0.7979262021671103 1.8887339379515848e-05 4.723829215936124 0.50199131196958 S(ph)FSLEGLTGGAGVGNKPSSSLEVSSANAEELR ddPTM_PC-9_Lapatinib_30min_R1 1 SFSLEGLTGGAGVGNKPSSSLEVSSANAEELR 32 1 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36;H0YMW2;H0YLH1 Q12802-2 AKAP13 A-kinase anchor protein 13 1 S(0.495)FS(0.495)LEGLT(0.002)GGAGVGNKPS(0.001)S(0.001)S(0.005)LEVSSANAEELR 54.562 0.00075129 9126800.0 10927.0 14903.0 17580.0 12730.0 18868.0 19640.0 20609.0 19190.0 16752.0 16391.0 True False 10771.17897623361 14868.493019137595 16134.640260762448 13666.206666035123 17758.221335915256 18800.042983076135 21676.03317938853 20081.637456539247 14865.213353619562 19224.162510365375 0.5602937953955578 0.7734273475435266 0.8392896310600213 0.710886971469707 0.9237448615168694 0.977938205263269 1.1275410914624315 1.044604020888376 0.7732567463266327 1.0 14.230633128921962 -6.392364902339035 2.628366485914949 0.9960535529958983 0.7298444674340895 0.577426925578894 0.10662124785941852 0.2191972978225241 2.947335230556923 0.037095544482917076 0.042965334737346254 4.051679626972926e-07 6.392364902339035 -0.2662090855618088 S(ph)FSLPADPILQAAK ddPTM_PC-9_AZD4547_30min_R2 1 SFSLPADPILQAAK 14 0 B7ZBB8 B7ZBB8 PPP1R3G Protein phosphatase 1 regulatory subunit 3G 1 S(0.952)FS(0.048)LPADPILQAAK 162.7 0.00011206 24342000.0 109220.0 95038.0 116680.0 165020.0 130730.0 102830.0 116350.0 147230.0 107160.0 125100.0 True False 143949.68808287152 125757.17493061606 115132.74696264238 126977.18853358495 112580.3960640582 96400.02384432728 126704.9246001836 124478.98650882514 112824.25882852403 120720.28707747662 1.1924233413269354 1.0417236238835883 0.9537149865188091 1.0518297430165382 0.9325723023819985 0.7985403794016749 1.0495744142727736 1.0311356071323474 0.9345923668663493 1.0 16.88130861620231 -4.411845517034266 1.2982942641737218 0.9654425571056389 1.514657804013361 0.47869959576343146 0.07089497368116966 2.8976327224986744 2.273865627303107 0.021773793845996793 2.6653577969003632 3.873954209085908e-05 4.411845517034266 0.549215246907722 S(ph)FSLPADPILQAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SFSLPADPILQAAK 14 0 B7ZBB8 B7ZBB8 PPP1R3G Protein phosphatase 1 regulatory subunit 3G 1 S(0.577)FS(0.423)LPADPILQAAK;S(0.998)FS(0.002)LPADPILQAAK;S(0.963)FS(0.037)LPADPILQAAK 180.95 3.8535e-05 86239100.0 329129.0 288982.0 262852.0 306190.0 331583.0 264343.0 271733.0 248679.0 231755.0 184447.0 True False 384844.03910593636 317670.22314449557 269119.38855176175 289035.16698137356 266611.6914384825 250480.38773074423 245992.48306344636 242151.43974718006 235143.97843761524 217885.78101835173 1.7662650463341725 1.4579667459701713 1.2351397475041972 1.326544419881301 1.2236305195887325 1.1495949233587077 1.12899741283589 1.1113687116957143 1.07920754323023 1.0 17.73321252530254 -1.5228787452803376 0.4064391337237794 1.0780468778337735 12.371135071952342 0.9352623284560225 0.05410108399897009 17.815204895118733 0.23383865869899284 0.03967187170405172 161.91541178029368 0.029999999999999995 1.5228787452803376 11.293088194118567 S(ph)FSMHDLTTIQGDEPVGQRPYQPLPEAK ddPTM_PC-9_AZD4547_30min_R2 1 SFSMHDLTTIQGDEPVGQRPYQPLPEAK 28 1 Q6NUK4 Q6NUK4 REEP3 Receptor expression-enhancing protein 3 1 S(0.493)FS(0.493)MHDLT(0.01)T(0.003)IQGDEPVGQRPYQPLPEAK 45.57899999999999 0.014688 14488000.0 38631.0 42799.0 64499.0 60580.0 52650.0 40834.0 52124.0 48868.0 37649.0 44030.0 True False 50914.85442528312 56632.93976993871 63643.70111710205 46614.21695166992 45340.45630515313 38280.64352483971 56762.93502243215 41316.57347492539 39639.04927804316 42488.52310168897 1.1983201746840477 1.3328997017476347 1.4979033506243982 1.0971013711186623 1.0671224367257612 0.9009643247241514 1.3359592397829372 0.9724172660942175 0.9329354466657718 1.0 15.37478557608602 -5.8953674195414125 6.627612094364354 1.0455158482006461 1.3405770626846223 0.5265422441824626 0.1308336531609043 0.17451077693925185 9.743372118238616 0.037377231568135535 0.05587204697656922 1.2724261342352478e-06 5.8953674195414125 0.29506121448397615 S(ph)FSMHDLTTIQGDEPVGQRPYQPLPEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SFSMHDLTTIQGDEPVGQRPYQPLPEAK 28 1 Q6NUK4 Q6NUK4 REEP3 Receptor expression-enhancing protein 3 1 S(0.443)FS(0.443)MHDLT(0.09)T(0.023)IQGDEPVGQRPYQPLPEAK;S(0.439)FS(0.439)MHDLT(0.099)T(0.023)IQGDEPVGQRPYQPLPEAK;S(0.438)FS(0.438)MHDLT(0.098)T(0.026)IQGDEPVGQRPYQPLPEAK 51.553999999999995 0.0056543 60932900.0 52293.0 51600.5 62150.0 58249.0 77927.0 58318.0 65013.0 51013.0 54661.0 42367.0 True False 61145.172066170904 56723.05662417575 63631.89170518753 54985.497375806 62657.76375365012 55259.70141702839 58854.49798664054 49673.962802741305 55460.313716547666 50047.80172301256 1.2217354201604351 1.1333775844562983 1.2714223105613218 1.0986595910869554 1.251958359738293 1.1041384339488247 1.1759656960033582 0.9925303628251196 1.1081468477574783 1.0 15.611019081718455 -7.573537753045174 1.169857010003529 1.0274956231888763 1.1898107453025588 0.4940896267391477 0.0648019250496095 0.3957889192968484 1.0041645825032395 0.04676654547092836 0.020773121385010616 2.669698681206273e-08 7.573537753045174 0.1623151221136825 S(ph)FSMHDLTTIQGDEPVGQRPYQPLPEAK ddPTM_PC-9_Lapatinib_30min_R1 1 SFSMHDLTTIQGDEPVGQRPYQPLPEAK 28 1 Q6NUK4 Q6NUK4 REEP3 Receptor expression-enhancing protein 3 1 S(0.529)FS(0.453)MHDLT(0.015)T(0.003)IQGDEPVGQRPYQPLPEAK 55.718 0.0014637 13942000.0 96111.0 86398.0 60271.0 41063.0 50896.0 48843.0 46277.0 51034.0 61209.0 24134.0 True False 94740.43951540107 86197.95073927735 55315.75103278805 44082.9100021524 47902.39734538599 46754.098748594086 48672.996624899955 53405.22594877668 54314.997860655414 28305.529743466388 3.3470647034002075 3.045268946403448 1.9542383249533173 1.5573956891701637 1.6923335397544728 1.6517655444829145 1.719557876712584 1.8867417933099775 1.9188829303995856 1.0 14.788796303778483 -5.2596513727459175 2.677929236890712 1.6759654128522266 3.319767640586901 0.8678056915931877 0.2415586949918626 0.08937158907189932 1.2433028233162875 0.0626313743204467 0.19918036802245234 5.499821915608024e-06 5.2596513727459175 1.6438022277346744 S(ph)FSPLQPGQAPTGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFSPLQPGQAPTGR 14 0 Q7Z3C6;H7C152;Q7Z3C6-2;H7C1G6 Q7Z3C6 ATG9A Autophagy-related protein 9A 1 S(0.554)FS(0.446)PLQPGQAPTGR 108.06 0.00072108 6372700.0 18316.0 15491.0 15871.0 14991.0 18749.0 21713.0 17046.0 16540.0 14683.0 13210.0 True False 21416.53704251019 17028.844103547588 16249.424831102682 14151.102871477742 15075.268040822655 20574.33205644806 15431.27947764716 16105.842525578606 14897.711097493077 15604.868429697539 1.3724266333288972 1.0912520140919668 1.0413048276766301 0.9068389736979042 0.966061848501907 1.318455977321357 0.9888759746464749 1.032103705208284 0.9546835440881594 1.0 13.929708572972988 -4.738264531441472 2.754105400419818 1.0306545560571654 1.460196290554702 0.49111575983757527 0.10533345668446477 0.4821215206129748 4.477004643171809 0.02820253343069879 0.5004621489270352 1.8269870481045637e-05 4.738264531441472 0.4295417344975365 S(ph)FSPLQPGQAPTGR ddPTM_PC-9_Lapatinib_30min_R1 2 SFSPLQPGQAPTGR 14 0 Q7Z3C6;H7C152;Q7Z3C6-2;H7C1G6 Q7Z3C6 ATG9A Autophagy-related protein 9A 1 S(0.891)FS(0.109)PLQPGQAPTGR;S(0.644)FS(0.356)PLQPGQAPTGR 116.86 0.00013842 11184500.0 35882.0 39668.0 35795.0 30671.0 34234.0 29936.0 31890.0 24143.0 35549.0 18989.1 True False 35370.3161000471 39576.15118319468 32852.07327269577 32926.64765545665 32220.42342663359 28655.707064224385 33541.10816103162 25264.77191835472 31545.097272434425 22271.340633614716 1.5881538826927086 1.7769990515730947 1.4750828795241575 1.478431325582601 1.44672132480442 1.286662870261774 1.5060210659436974 1.1344073234739152 1.4163986708919796 1.0 14.442900783982006 -1.5228787457543376 0.07764203283745756 0.6166810590892547 3.471136200292646 0.7010290151316595 0.1153711715477741 104.47915638983596 0.5955341497119228 3.422260502061953 32.11027127606961 0.02999999996725724 1.5228787457543376 2.8544551412033914 S(ph)FSSPENFQR ddPTM_PC-9_Lapatinib_30min_R1 1 SFSSPENFQR 10 0 G3V1T9;J3KPD3;Q9Y580;I3L521;F5GXV8;F5GY08 G3V1T9 RBM7 RNA-binding protein 7 1 S(0.898)FS(0.028)S(0.074)PENFQR 149.49 0.00015646 33214000.0 25834.0 21144.0 26547.0 19467.0 33069.0 26794.0 42859.0 36500.0 40909.0 31526.0 True False 25465.602422624634 21095.042367083497 24364.40813438342 20898.66812000829 31123.94643615547 25648.083079864642 45078.02930930242 38195.92324980108 36301.39762913218 36975.22709424553 0.6887206495775074 0.5705182638449983 0.6589387016415448 0.5652072958670417 0.8417513260114446 0.6936558635459 1.2191413779394458 1.0330138920430196 0.9817761913024676 1.0 15.174271387637436 -7.200430175813902 7.752329048104755 1.060794524194915 0.6667500381046617 0.8061545418840061 0.09337168780273714 0.13019938871714373 15.033813713602326 0.03686763136646082 0.028464342156832665 6.303326802935398e-08 7.200430175813902 -0.39404448609025333 S(ph)FSSSAEEHS ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFSSSAEEHS 10 0 Q96EQ0 Q96EQ0 SGTB Small glutamine-rich tetratricopeptide repeat-containing protein beta 1 S(0.581)FS(0.342)S(0.039)S(0.039)AEEHS 128.27 0.00028522 5124600.0 13778.0 3264.9 10506.0 21055.0 34068.0 42928.0 53449.0 43046.0 46861.0 40365.0 True False 16110.343272095735 3589.017695027598 10756.502884226873 19875.356611231018 27392.619959184263 40676.78010957502 48385.923782750375 41916.08811100703 47546.25347269793 47682.85497083583 0.3378644857139798 0.07526851521836815 0.2255842879124132 0.41682396373680525 0.5744752485130841 0.8530693083384808 1.0147446878410398 0.8790599500940974 0.9971352072307446 1.0 15.541182998087734 -6.452072209724033 1.2236772480400524 0.9759336059663807 0.19096902387499226 0.9495221618257681 0.07572867090012816 0.08868456254771803 0.2760601340351913 0.03259652248728697 0.0393653108410073 3.5312445124911845e-07 6.452072209724033 -0.7849645820913884 down S(ph)FSTTSASSQK ddPTM_PC-9_AZD4547_30min_R2 3 SFSTTSASSQK 11 0 B5MCH3;Q8N3C7;Q8N3C7-3;Q8N3C7-2 B5MCH3 CLIP4 CAP-Gly domain-containing linker protein 4 1 S(0.962)FS(0.037)T(0.001)TSASSQK;S(0.746)FS(0.127)T(0.127)T(0.001)SASSQK;S(0.952)FS(0.047)T(0.001)TSASSQK 166.04 0.0017392 113178000.0 69515.0 81844.0 102258.0 156478.0 118836.0 105470.0 105734.0 130365.0 129136.0 120665.0 True False 91619.32399817632 108298.47245334843 100901.99210580981 120404.4146610006 102337.67265867391 98874.94422698834 115144.12116610105 110220.08473967915 135961.86532363098 116440.55507756775 0.7868334528046814 0.930075199153805 0.8665536851708856 1.0340419159011418 0.8788834147217943 0.8491452497896635 0.9888661307857638 0.9465781459582978 1.167650439600352 1.0 16.829234096421203 -7.889547853341457 1.9412118034583554 1.0754333804403957 0.9011305489231649 0.44267445041369247 0.07736930971656167 0.3201302807028733 2.273251077985976 0.05901694471543928 0.021509086657953373 1.2895914546421205e-08 7.889547853341457 -0.1743028315172308 S(ph)FSTTSASSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SFSTTSASSQK 11 0 B5MCH3;Q8N3C7;Q8N3C7-3;Q8N3C7-2 B5MCH3 CLIP4 CAP-Gly domain-containing linker protein 4 1 S(0.977)FS(0.023)TTSASSQK;S(0.979)FS(0.018)T(0.001)T(0.002)S(0.001)ASSQK;S(0.885)FS(0.109)T(0.006)TSASSQK;S(0.988)FS(0.012)TTSASSQK;S(0.867)FS(0.132)T(0.002)TSASSQK 182.41 0.0015114 87793400.0 109460.0 112894.0 96463.0 117414.0 117582.0 119439.0 133184.0 156944.0 119967.0 98600.5 True False 127989.4160664535 124101.37022954645 98763.0437579649 110835.67424132381 94542.65116944956 113175.40857965735 120567.84735134123 152824.38629591375 121721.2904197339 116475.9901288712 1.0988480623761483 1.0654673988367764 0.8479262004872561 0.951575291342818 0.8116921870751715 0.9716629878349862 1.0351304781177884 1.3120677156453102 1.0450333178971838 1.0 16.829673068870655 -7.527905080298291 24.98175326937766 1.1418501554814013 0.9552071100153733 0.29139574754061304 0.11119746022361812 155.85391748955917 774603.8438276853 0.05278260426257112 0.03060911330925737 2.965479455937464e-08 7.527905080298291 -0.18664304546602806 S(ph)FSTTSASSQK ddPTM_PC-9_Lapatinib_30min_R1 2 SFSTTSASSQK 11 0 B5MCH3;Q8N3C7;Q8N3C7-3;Q8N3C7-2 B5MCH3 CLIP4 CAP-Gly domain-containing linker protein 4 1 S(0.58)FS(0.413)T(0.006)TSASSQK;S(0.911)FS(0.044)T(0.044)T(0.001)SASSQK 166.11 0.00096398 27327000.0 37477.0 26194.1 22892.8 22449.9 35855.0 30327.0 30814.8 28299.0 32944.0 32727.0 True False 36942.5711075599 26133.44917081072 21010.64235276352 24100.940536671013 33746.079393642205 29029.9849056899 32410.239566025604 29613.87485057866 29233.49980430054 38383.81834401361 0.9624516971308955 0.680845478597012 0.5473828102367613 0.6278932523249039 0.8791746326849029 0.7563078963512616 0.8443724716376568 0.7715197739100721 0.7616099977937665 1.0 15.22821061458369 -6.262842485075099 24.998817005210203 0.8205577232091816 0.6917105715959291 0.2128679276346479 0.1202215369648679 211.71848098411354 3772130.135467171 0.037204608618440396 0.044494117038811426 5.459558387386074e-07 6.262842485075099 -0.12884715161325255 S(ph)FTFGAYGGVDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFTFGAYGGVDK 12 0 P47736-4 P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 S(0.598)FT(0.402)FGAYGGVDK 118.76 0.00057008 4075700.0 6443.3 6765.0 11121.0 12787.0 17289.0 13434.0 18043.0 19951.0 13551.0 13319.0 True False 7534.023429024136 7436.5844916725455 11386.166816627358 12070.585846013335 13901.344560124951 12729.497390794606 16333.83641999225 19427.307389831843 13749.157739026678 15733.629266854012 0.47884841451654386 0.4726553782056614 0.7236834314263754 0.7671838227078606 0.883543416737985 0.809063006054922 1.0381480421940978 1.234763261567329 0.8738707075037027 1.0 13.941563874293006 -5.624722343302248 0.5515418145334536 1.0559303818740888 0.3037639225916813 0.7920595701780864 0.10272841425023545 0.7892738441146676 0.3447141700560205 0.0692375183574613 0.34379909206581893 2.372890276422452e-06 5.624722343302248 -0.7521664592824076 down S(ph)FTGGLGQLVVPSK ddPTM_PC-9_AZD4547_30min_R2 2 SFTGGLGQLVVPSK 14 0 Q9Y3Q8 Q9Y3Q8 TSC22D4 TSC22 domain family protein 4 1 S(0.688)FT(0.312)GGLGQLVVPSK;S(0.936)FT(0.064)GGLGQLVVPSK 135.69 1.8322000000000002e-05 135046000.0 168864.0 155634.0 229700.0 347610.0 305276.0 275149.0 307332.0 444454.0 318849.0 344984.0 True False 222559.23941060298 205939.6469112515 226654.02791668643 267473.88502096373 262893.69684733 257943.88953362743 334683.952619026 375773.8468368775 335702.7071968656 332906.2151649567 0.668534347730107 0.6186116014962574 0.6808344740706574 0.8034511608274694 0.7896929671831596 0.7748244934562575 1.0053400548655675 1.1287678923347217 1.008400239780814 1.0 18.344756279441754 -7.01386184465666 1.0037586512447674 1.0694676556033764 0.6749658966310087 0.8584488017613904 0.062496434376303214 0.19444024177333663 0.40342586062798563 0.04339227003573681 0.030803888939874957 9.68585928422041e-08 7.01386184465666 -0.3945017589723677 S(ph)FTGGLGQLVVPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFTGGLGQLVVPSK 14 0 Q9Y3Q8 Q9Y3Q8 TSC22D4 TSC22 domain family protein 4 1 S(0.877)FT(0.123)GGLGQLVVPSK;S(0.942)FT(0.058)GGLGQLVVPSK 168.55 0.00034706 142205000.0 298490.0 218400.0 267863.0 323680.0 403280.0 329420.0 319300.0 287860.0 277320.0 257052.0 True False 349018.4615537715 240081.30864468383 274249.8697960845 305545.25898471836 324260.17896970356 312144.63528923347 289053.5924681878 280303.9800128809 281375.2803621046 303653.4927774872 1.149397157797645 0.7906423418636974 0.9031671833824442 1.0062300162923448 1.0678625034203595 1.0279632631065057 0.9519192083853355 0.9231047449807649 0.9266327806355655 1.0 18.212066438335086 -4.712927285158033 24.59685172338975 0.958525424283568 1.1494011771359502 0.3836240192979863 0.07371346956986911 17388.339373660307 8815368.391577372 0.019943671094440663 19.55515434335276 1.9367462103079827e-05 4.712927285158033 0.19087575285238223 S(ph)FTGGLGQLVVPSK ddPTM_PC-9_Lapatinib_30min_R1 2 SFTGGLGQLVVPSK 14 0 Q9Y3Q8 Q9Y3Q8 TSC22D4 TSC22 domain family protein 4 1 S(0.981)FT(0.019)GGLGQLVVPSK;S(0.941)FT(0.059)GGLGQLVVPSK 157.83 0.00023847 148986000.0 316900.0 227778.0 260820.0 246280.0 214695.0 189353.0 164868.0 159150.0 218128.0 204198.0 True False 312380.9478876582 227250.59403563914 239376.3863943149 264392.25276599586 202067.06220661016 181254.81359340192 173404.05833468036 166544.69000563983 193560.1276503299 239493.35222326792 1.304340788534459 0.9488805928265789 0.9995116113751501 1.1039648921842136 0.8437272280452818 0.7568260743389108 0.7240453930137662 0.6954042292179299 0.8082066823712221 1.0 17.869626085105445 -6.368644086346741 3.647098761783105 0.7750443031532421 1.0734871166775384 0.5828305207773166 0.11713127993902035 0.1701028681558874 4.135706513089593 0.036779229149481577 0.04232173895866904 4.2791342673573204e-07 6.368644086346741 0.29844281352429625 S(ph)FTLDDESLK ddPTM_PC-9_AZD4547_30min_R2 2 SFTLDDESLK 10 0 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 S(0.998)FT(0.002)LDDESLK;S(0.989)FT(0.011)LDDESLK 182.92 0.0005442 39351000.0 138725.0 142782.0 145935.0 180809.0 183909.0 192030.0 174697.0 205670.0 191426.0 202158.0 True False 182836.66434074662 188933.48924580932 143999.80654776478 139126.27852120323 158376.40985041636 180022.33374332578 190244.69456706737 173888.4273264283 201544.38755607567 195080.50995210663 0.9372369612199294 0.968489826544915 0.7381557828771185 0.7131736458724632 0.8118515267839861 0.9228104529126067 0.9752111813413524 0.8913675044683802 1.0331344100215647 1.0 17.57371012321918 -6.904628882061775 3.996762966718408 0.9642543103842023 0.8295830171310064 0.4056082308954565 0.08045975339933291 0.2704210276757069 8.116290019588327 0.0329149916451423 0.02869560928457326 1.2455785421452925e-07 6.904628882061775 -0.13467129325319593 S(ph)FTLDDESLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SFTLDDESLK 10 0 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 S(1)FTLDDESLK;S(0.988)FT(0.012)LDDESLK;S(0.862)FT(0.138)LDDESLK 171.67 6.2271e-06 22529000.0 54945.1 74276.2 74374.6 86617.7 107197.0 95501.8 123244.0 129185.0 120012.3 89396.1 True False 64246.22021480819 81649.85026169526 76147.97253124112 81764.7910873722 86192.51737010336 90493.51748668948 111569.43611070883 125794.03063282205 121767.25284653465 105602.9052708618 0.6083754992348223 0.7731780678975722 0.7210783863940914 0.7742664927413975 0.8161945653770362 0.8569226126362895 1.0564996845924213 1.191198578393008 1.153067262062656 1.0 16.688290000063184 -7.1037699440595725 1.4465812615058982 1.136478760503075 0.7281614218933853 0.8671966391850124 0.06728684784560825 0.13460452065958128 0.5620166755305439 0.03614823213365979 0.0244145663596414 7.874628166949543e-08 7.1037699440595725 -0.4083173386096898 S(ph)FTLDDESLK ddPTM_PC-9_Lapatinib_30min_R1 2 SFTLDDESLK 10 0 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 S(0.989)FT(0.011)LDDESLK;S(0.623)FT(0.377)LDDESLK 217.22 9.637499999999999e-08 29022000.0 76464.0 92918.0 112348.0 112524.0 138947.0 155200.0 162153.0 154135.0 171336.0 159696.0 True False 75373.60933821989 92702.85407986485 103111.18111582121 120799.39032905991 130774.41064031259 148562.45778887058 170548.4889192775 161296.67479748197 152038.33543193425 187299.24081845582 0.4024234642321777 0.4949451672883141 0.5505157450999182 0.6449539773957096 0.6982111089658327 0.7931823809839583 0.9105668991183239 0.8611710015088773 0.8117402652971828 1.0 17.514985526342016 -5.2688780800642965 0.3236758880347804 0.9738773940695443 0.07769225542384613 0.9508477622330306 0.04055704140464109 1.0935692884737949 0.1181846843744037 0.04721725734059403 0.37614263564005024 5.384209127573438e-06 5.2688780800642965 -0.8961851386456982 down S(ph)FTPDHVVYAR ddPTM_PC-9_AZD4547_30min_R2 2 SFTPDHVVYAR 11 0 Q6NZI2;Q6NZI2-3;Q6NZI2-2 Q6NZI2 PTRF Polymerase I and transcript release factor 1 S(1)FTPDHVVYAR;S(0.99)FT(0.009)PDHVVY(0.001)AR 130.1 0.00022626 18306700.0 17263.6 13174.3 6349.1 15071.8 23402.7 19542.1 18702.8 21442.3 13490.4 16332.0 True False 22753.065694812918 17432.634837521986 6264.906785571757 11597.229366988757 20153.639065006788 18320.129397726647 20367.312967875532 18128.88523003587 14203.475002802548 15760.221651073902 1.4437021381144424 1.1061160955394385 0.3975138753930447 0.7358544583793034 1.2787662198668075 1.1624284101663198 1.2923240179485485 1.1502937986154889 0.9012230485879444 1.0 13.944000204486915 -6.265616522991376 24.973140832488113 1.1480076334662146 0.8966564059768788 0.12104626927809004 0.2718602717058097 723.236797676242 4323880.735334066 0.08979886078593595 0.10547922062907526 5.424796822769877e-07 6.265616522991376 -0.2513512274893358 S(ph)FTPDHVVYAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFTPDHVVYAR 11 0 Q6NZI2;Q6NZI2-3;Q6NZI2-2 Q6NZI2 PTRF Polymerase I and transcript release factor 1 S(0.995)FT(0.005)PDHVVYAR 172.17 0.0026745000000000002 11946000.0 27373.0 23147.0 30597.0 24939.0 29341.0 25559.0 33852.0 17476.0 20305.0 18310.0 True False 32006.708258606217 25444.88118680626 31326.548519768665 23541.74868332892 23591.841676130858 24218.641045952016 30645.29349274385 17017.273517352587 20601.922211714034 21629.458058119737 1.4797739348162189 1.1763993863569875 1.4483279440285663 1.0884113980142607 1.0907273595453972 1.1197063274019616 1.4168313145155087 0.7867637493101346 0.9524936850639231 1.0 14.400709897523496 -4.85626410626583 0.26273063733871693 0.9279206186779007 1.7738975706481128 0.41647802900230435 0.16577674084187316 9.498826079599214 0.5722949911869556 0.2334587576691159 2.611506174850331 1.3923098440237551e-05 4.85626410626583 0.8459769519702122 S(ph)FTPDHVVYAR ddPTM_PC-9_Lapatinib_30min_R1 2 SFTPDHVVYAR 11 0 Q6NZI2;Q6NZI2-3;Q6NZI2-2 Q6NZI2 PTRF Polymerase I and transcript release factor 1 S(1)FTPDHVVYAR;S(0.999)FT(0.001)PDHVVYAR 159.94 0.00031096 23102000.0 28438.0 26356.0 27448.0 26535.0 19568.1 20837.9 17743.8 18124.5 23822.0 20442.7 True False 28032.46890510952 26294.974301307797 25191.331392344022 28486.472418165115 18417.142830364803 19946.71159251742 18662.48714291981 18966.630436740266 21138.91550321903 23976.193456814475 1.169179292601269 1.096711800756441 1.050681019809013 1.1881148886070876 0.768142902397641 0.8319382152319177 0.7783757324336898 0.7910609526446577 0.8816627018502372 1.0 14.549315009240171 -6.262614544981755 24.99999945667106 0.8277458154046811 1.1186752792340195 0.7860680729002412 0.07239471850128631 44.532875069498935 947372.3131012429 0.02097121075098505 0.02512935928663112 5.462424596683545e-07 6.262614544981755 0.2909294638293385 S(ph)FVDAEVDVTR ddPTM_PC-9_AZD4547_30min_R2 1 SFVDAEVDVTR 11 0 A0A2R8YHB3;A0A1B0GUB2;A0A3B3IRP5;Q6P1J9 A0A2R8YHB3 CDC73 Parafibromin 1 S(1)FVDAEVDVTR 117.2 0.0020047999999999997 0.0 4670.3 3948.5 6533.7 7586.0 6230.3 5397.4 4997.7 7337.1 5371.7 4849.4 True False 6155.35825172529 5224.775407874087 6447.058868956257 5837.1649025316665 5365.3303878061815 5059.899724762937 5442.485618172227 6203.31978478504 5655.637095457098 4679.623982042481 1.3153531726792087 1.1164947072507454 1.3776873726812464 1.2473576776534003 1.1465302358469442 1.081262029637364 1.1630177208803827 1.3256021869683476 1.2085665679892137 1.0 12.19217689544583 -11.52974600855969 2.903359111908856 0.7720153234158155 1.2177519689790182 0.33990303272523326 0.09200477008850258 73363502.87380622 93060234.5003727 111486044.37835784 0.02370393414944953 2.9529357075398334e-12 11.52974600855969 0.4457366455632027 S(ph)FVDAEVDVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFVDAEVDVTR 11 0 A0A2R8YHB3;A0A1B0GUB2;A0A3B3IRP5;Q6P1J9 A0A2R8YHB3 CDC73 Parafibromin 1 S(1)FVDAEVDVTR;S(1)FVDAEVDVTR 106.79 0.0023906999999999995 1913390.0 5300.0 6119.6 8908.4 8888.6 9160.4 7173.700000000001 7277.2 8251.5 7587.700000000001 4852.7 True False 6197.185320228439 6727.113444972553 9120.810041295132 8390.600559230013 7365.485378481614 6797.4985434228975 6587.850933634513 8034.906868186936 7698.655757981904 5732.456096047936 1.0810698270329355 1.1735132955680818 1.591082406646462 1.4637007974670146 1.2848742764134766 1.185791644895322 1.1492196055677257 1.4016517062775855 1.342994281855818 1.0 12.484937685142997 -6.520456289322269 24.374635756025665 1.2366949259565392 1.340079355353658 0.08289402234044496 0.1667011808212241 213.56370885742095 2148907.2774932752 0.058259636146822516 0.05925751967353214 3.0167804894629255e-07 6.520456289322269 0.1033844293971189 S(ph)FVDAEVDVTR ddPTM_PC-9_Lapatinib_30min_R1 1 SFVDAEVDVTR 11 0 A0A2R8YHB3;A0A1B0GUB2;A0A3B3IRP5;Q6P1J9 A0A2R8YHB3 CDC73 Parafibromin 1 S(1)FVDAEVDVTR 84.169 0.035787 0.0 2703.9 3147.5 4356.8 2185.6 3527.3 3693.2 1974.1 3236.7 3468.2 2695.5 True False 2665.34189016547 3140.212157131822 3998.6007217343463 2346.336314947868 3319.8311489386206 3535.2504452696908 2076.3092386545163 3387.088898154279 3077.574794234917 3161.413583472017 0.8430854805268038 0.9932936878455142 1.2648141776321749 0.7421794880665402 1.0501097250593268 1.1182499068619514 0.6567660901786262 1.0713843060149109 0.9734806006795783 1.0 11.626354068969091 S(ph)FVGLGPR ddPTM_PC-9_AZD4547_30min_R2 1 SFVGLGPR 8 0 A0A286YEX4;P08651-2;P08651 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 S(1)FVGLGPR 76.17 0.025336 2169900.0 6441.4 7084.7 10166.0 9896.2 10378.0 10530.0 8049.0 12548.0 6667.6 10243.0 True False 8489.631210556769 9374.690726140441 10031.192197653596 7614.783984765861 8937.19383731964 9871.557435386243 8765.345407020885 10608.994924354663 7020.035723824818 9884.395687726552 0.858892286262714 0.9484333713775733 1.0148513388743958 0.7703843740514287 0.9041720019785275 0.9987011596109765 0.8867861712481633 1.0733073886881972 0.7102139519304749 1.0 13.270937049810223 -6.563419023710614 24.999123003934166 0.9372218264948887 0.9009701209833517 0.02478487601209678 0.10693983895056408 739.7416830681891 456156.37403803936 0.03395586011181421 0.03395591758467395 2.7326309085217993e-07 6.563419023710614 -0.036251705511537 S(ph)FVGLGPR ddPTM_PC-9_Lapatinib_30min_R1 1 SFVGLGPR 8 0 A0A286YEX4;P08651-2;P08651 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 S(1)FVGLGPR 89.029 0.028094 0.0 9189.3 9357.4 16097.0 10225.0 8085.6 12150.0 10459.0 9381.3 13290.0 7848.3 True False 9058.258896888769 9335.733515216936 14773.56679621691 10976.98060960008 7610.020904901231 11630.372823033347 11000.515843719964 9817.18944611942 11793.14025009575 9204.868197797607 0.9840726344192613 1.0142169680876736 1.6049732031743478 1.1925190425025831 0.8267387149250041 1.2635023742997293 1.1950758671755877 1.0665214574683775 1.2811851290730512 1.0 13.16818134879619 -6.019922030084424 24.94415605782918 1.1110649237255212 1.2184581373809023 0.04738658002416152 0.20011040583205128 2504.600166334344 3135983.8181041577 0.06081128112767599 0.07960928904796555 9.551640534907748e-07 6.019922030084424 0.10739321365538101 S(ph)FVLNLGK ddPTM_PC-9_AZD4547_30min_R2 1 SFVLNLGK 8 0 P09382 P09382 LGALS1 Galectin-1 1 S(1)FVLNLGK 102.52 0.0042528 3675200.0 16267.0 19208.0 20420.0 29487.0 23433.0 22510.0 20990.0 26016.0 21982.0 19478.0 True False 21439.56762538065 25416.610367087622 20149.217457809016 22689.227719608632 20179.732433022844 21102.44614155217 22858.06933698202 21995.82498820616 23143.923642857557 18796.08114864179 1.1406402992109808 1.3522292315131992 1.0719903419476886 1.2071254396158084 1.0736138173398466 1.1227045666951185 1.2161082491726605 1.1702346257318421 1.2313164355821022 1.0 14.198144280986472 -10.77195794612809 3.455301170000529 0.9995704016800834 1.1756439791115616 0.31026732397966583 0.07881722172815181 43966919.60591315 59100232.97783995 201770.22530632242 0.019271334084716943 1.690604629390713e-11 10.77195794612809 0.17607357743147822 S(ph)FVLNLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFVLNLGK 8 0 P09382 P09382 LGALS1 Galectin-1 1 S(1)FVLNLGK 82.831 0.015913999999999998 3593000.0 16964.0 16978.0 16196.0 17045.0 19595.0 16198.0 18251.0 17828.0 14786.0 12664.0 True False 19835.670145727403 18663.463636306933 16582.174063672035 16090.0239106356 15755.50041388447 15348.548365050698 16522.133154202653 17360.033890327406 15002.21727763623 14959.882951831152 1.325924153925244 1.2475674907618477 1.108442767705098 1.0755447728062681 1.0531834015423183 1.025980511643774 1.10442930652611 1.1604391522463393 1.0028298567536515 1.0 13.868811266975978 -5.157582955928409 1.812728268244766 1.0663109647872444 1.338749265082477 0.7998976926131581 0.045439304597323656 0.20117480619566136 1.0818700351223771 0.013054488918103957 0.07223575919628843 6.956920557231191e-06 5.157582955928409 0.27243830029523264 S(ph)FVLNLGK ddPTM_PC-9_Lapatinib_30min_R1 2 SFVLNLGK 8 0 P09382 P09382 LGALS1 Galectin-1 1 S(1)FVLNLGK;S(1)FVLNLGK 108.43 0.0037941000000000003 5203700.0 33116.0 32209.0 32202.0 22224.0 32052.0 32649.0 28847.0 26125.0 32631.0 23472.0 True False 32643.759767269352 32134.422039415054 29554.475863314692 23858.427097090676 30166.764376656556 31252.678378536282 30340.556510544975 27338.862874001465 28955.753160336677 27529.10392552594 1.1857908581252776 1.1672890671032305 1.0735720255649426 0.866661957528095 1.095813523689919 1.1352595588684495 1.1021265564118912 0.9930894571781512 1.0518233081131239 1.0 14.748670030411382 -5.301777573088928 4.24225475803848 1.0396851496943746 1.1790445596623045 0.3782937639226098 0.07107427483026064 0.22564758226408974 9.153234824421014 0.02007498238258792 0.047629473374657914 4.991400600284765e-06 5.301777573088928 0.13935940996792984 S(ph)FVMAVS(ph)VDGRTFEGSGRS(ph)KK ddPTM_PC-9_AZD4547_30min_R2 1 SFVMAVSVDGRTFEGSGRSKK 21 3 Q9NS39 Q9NS39 ADARB2 Double-stranded RNA-specific editase B2 3 S(0.994)FVMAVS(0.995)VDGRT(0.011)FEGS(0.038)GRS(0.962)KK 52.685 0.01719 9874400.0 1063.8 0.0 16858.0 19399.0 13603.0 4596.4 3276.1 14308.0 5397.2 9356.7 True False 1402.0662715854146 0.0 16634.451905178474 14926.860261562315 11714.458254871757 4308.9863813874 3567.6665533533483 12097.02736513122 5682.484973397821 9029.124780957829 0.15528263321184055 0.0 1.842310557083015 1.6531901622450322 1.2974079480634957 0.4772319007568631 0.3951287239796992 1.3397785121591754 0.6293505861589179 1.0 13.140370434564547 -5.231363770344742 24.686075574150127 1.0737833397588064 0.07764078194237373 0.4357284294375433 0.45591387932244404 610.3411096740459 500965.9723233742 0.12750012117554735 0.33722874223244337 5.869974703285636e-06 5.231363770344742 -0.9961425578164327 S(ph)FVPEEEKHEER ddPTM_PC-9_AZD4547_30min_R2 2 SFVPEEEKHEER 12 1 A0A0U1RRH6;O94880;O94880-2;B4DG57 A0A0U1RRH6 PHF14 PHD finger protein 14 1 S(1)FVPEEEKHEER;S(1)FVPEEEKHEER 77.204 0.0075089 21941000.0 98670.0 124106.0 116707.0 116532.0 107924.0 130501.0 124426.0 140981.0 120420.0 118272.0 True False 130045.00753650362 164220.8374748948 115159.38892500084 89667.34780145259 92940.61550384328 122340.75184001306 135499.6729548985 119195.62587109063 126785.1553576975 114131.3332791948 1.1394330005624296 1.438876010264141 1.009007654745355 0.7856505766221361 0.8143304107075175 1.0719295773119193 1.1872258832150082 1.0443725000522621 1.1108707110916523 1.0 16.80033539367782 -5.287793047335321 20.39974752121146 0.9990593112738788 1.2891540263368337 0.4213303782717115 0.13411666579375703 66.41279080014247 51408.74958325336 0.03849621703092646 0.08025201416354141 5.154742229966217e-06 5.287793047335321 0.2900947150629549 S(ph)FVPEEEKHEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFVPEEEKHEER 12 1 A0A0U1RRH6;O94880;O94880-2;B4DG57 A0A0U1RRH6 PHF14 PHD finger protein 14 1 S(1)FVPEEEKHEER 98.0 0.0017908000000000002 5389400.0 13636.0 11118.0 19769.0 19381.0 25137.0 26454.0 20573.0 16327.0 20132.0 20616.0 True False 15944.305476723592 12221.72156369776 20240.367934350008 18295.145404049777 20211.58529746435 25066.705670394556 18624.176504378443 15898.433549886457 20426.39241399788 24353.51760383378 0.6547023611165561 0.5018462532810369 0.8311065474649841 0.751232150593708 0.8299246797219388 1.02928480715445 0.7647427697034858 0.6528187758545275 0.8387450530260284 1.0 14.571842548698417 -5.271969072515454 24.380046705942412 0.825770282472522 0.5782743096060875 0.46372914379483665 0.11084369870311091 410.47199183005966 950392.9863862799 0.029696712157020078 0.06294237851330453 5.346024287723398e-06 5.271969072515454 -0.24749597286643454 S(ph)FVPEEEKHEER ddPTM_PC-9_Lapatinib_30min_R1 1 SFVPEEEKHEER 12 1 A0A0U1RRH6;O94880;O94880-2;B4DG57 A0A0U1RRH6 PHF14 PHD finger protein 14 1 S(1)FVPEEEKHEER 90.229 0.0029757 7874200.0 18294.0 28995.0 33182.0 24201.0 66863.0 84948.0 119230.0 99140.0 86734.0 90810.0 True False 18033.12420529127 28927.8638589475 30453.90404622411 25980.822272169346 62930.24979771582 81314.97206345976 125403.14600312954 103746.4063283638 76965.10357048943 106506.38750328124 0.16931495498085228 0.2716068447824906 0.2859350012719743 0.243936752350829 0.5908589266139279 0.7634750738396289 1.1774237108480103 0.9740862380218049 0.7226336877505896 1.0 16.70058043017403 -6.5964056958314545 1.7875258342086118 0.9642847344826129 0.23951126788068858 0.8896578516412348 0.114588562847076 0.10956050243455803 0.7154987184418314 0.04614830754903824 0.04765072041439305 2.532761547958491e-07 6.5964056958314545 -0.7247734666019243 down S(ph)FYKHILGIPVNY(ph)QDVASIDPEY(ph)AK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFYKHILGIPVNYQDVASIDPEYAK 25 1 H0YAU8;H0YBH3;Q8IYU2-2;Q8IYU2-3;Q8IYU2 H0YAU8 HACE1 E3 ubiquitin-protein ligase HACE1 3 S(0.989)FY(0.011)KHILGIPVNY(0.838)QDVAS(0.392)IDPEY(0.77)AK 42.181000000000004 0.043122 0.0 3516.8 2803.9 1141.2 3685.3 3695.2 2530.7 3364.8 2918.0 2265.5 2910.2 True False 4112.124780033842 3082.2526616704595 1168.4105360251015 3478.824588903806 2971.1520862151483 2397.9856369572653 3046.0617849575974 2841.4055918765644 2298.628651595082 3437.7962228694764 1.1961514044021824 0.896578058107746 0.3398719587427573 1.011934496222142 0.864260675618281 0.6975357122696769 0.8860507102468964 0.8265194932074497 0.6686343525261225 1.0 11.747268315525579 -4.829109582552443 4.336921148280033 0.7823872635972163 1.2078106284240766 0.3067625760863435 0.18390519725161064 0.22807700064751887 7.505697818639002 0.04478624047273322 0.25404985590637974 1.4821440586999978e-05 4.829109582552443 0.4254233648268603 S(ph)GAEVEAGDAAER ddPTM_PC-9_AZD4547_30min_R2 2 SGAEVEAGDAAER 13 0 A0A087WZ13;Q8IY67-2;E9PAU2;Q8IY67;Q8IY67-3;K7EKR9 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 S(1)GAEVEAGDAAER;S(1)GAEVEAGDAAER 129.17 9.599299999999999e-05 18019700.0 14140.599999999999 12118.8 23205.3 27908.7 32762.0 21561.3 14419.7 29261.0 18784.4 20032.3 True False 18637.016657248274 16035.965103949462 22897.58255992632 21474.780400116713 28213.56181328445 20213.068502525508 15703.025365339672 24739.384800887936 19777.30503488736 19330.975274357574 0.9641012102462397 0.829547649632612 1.184502190652524 1.1108999983359806 1.459500175902122 1.0456310773589383 0.8123245279905584 1.2797794446359148 1.0230888382088947 1.0 14.238626804888844 -5.262387834698702 24.978537845491992 1.123404072907437 0.8968244224018392 0.21251678020143716 0.16687311356250112 119.15908866469852 3138276.7947375686 0.04427911838767033 0.101658661521728 5.465276834429526e-06 5.262387834698702 -0.2265796505055978 S(ph)GAEVEAGDAAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGAEVEAGDAAER 13 0 A0A087WZ13;Q8IY67-2;E9PAU2;Q8IY67;Q8IY67-3;K7EKR9 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 S(1)GAEVEAGDAAER 104.7 0.0030716999999999997 0.0 7422.0 8240.3 11433.0 7964.8 11694.0 8225.0 9070.8 5798.7 8827.0 8664.2 True False 8678.398008818016 9058.34252575451 11705.606079893949 7518.558078230004 9402.6446460814 7793.666520715024 8211.548157095029 5646.490269230514 8956.078175956642 10234.950874230539 0.8479178957925829 0.885040156720392 1.1436895226694455 0.7345964011571523 0.9186799977472573 0.7614757136097099 0.8023045990157106 0.5516870905015473 0.8750484771261745 1.0 13.321216557272368 -6.335370511935461 1.433538271763269 0.7732325668678787 0.9350011350994476 0.10430494489862219 0.1428135704451049 0.7087364034644332 2.9346453778738786 0.05422155663818329 0.07057065168266817 4.6198671606844754e-07 6.335370511935461 0.16176856823156893 S(ph)GAEVEAGDAAER ddPTM_PC-9_Lapatinib_30min_R1 1 SGAEVEAGDAAER 13 0 A0A087WZ13;Q8IY67-2;E9PAU2;Q8IY67;Q8IY67-3;K7EKR9 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 S(1)GAEVEAGDAAER 185.66 4.467e-05 8645400.0 13981.0 13120.0 15767.0 10303.0 10704.0 13255.0 10660.0 10784.0 17188.0 11195.0 True False 13781.628376198614 13089.621446090392 14470.69812238006 11060.716989800458 10074.411764873694 12688.114548914156 11211.92264021941 11285.064008927531 15252.106442336008 13130.040833600162 1.0496257057275116 0.9969216099156116 1.1021061020121976 0.8423977602183655 0.7672795456273812 0.9663423526029635 0.8539137678481372 0.8594843041195058 1.1616191172311832 1.0 13.680583782477953 -5.759360920350789 24.999464924017353 0.908338770684 1.0442881890515594 0.22940773591821417 0.10541675464468116 76.91512196212219 925097.603887775 0.02910768409231733 0.04738406731376579 1.7403599464213776e-06 5.759360920350789 0.13594941836755936 S(ph)GAGPGGSGGGGAR ddPTM_PC-9_Lapatinib_30min_R1 1 SGAGPGGSGGGGAR 14 0 A0A3B3IUB1;Q13144;H7C2X0;C9JRD9;A0A3B3IT53;A0A3B3ISS1;A0A3B3IS56;A0A3B3IRP4;A0A3B3ITQ2;A0A3B3IUF2;A0A3B3ISM8;A0A3B3ISX3 A0A3B3IUB1 EIF2B5 Translation initiation factor eIF-2B subunit epsilon 1 S(1)GAGPGGSGGGGAR 109.6 0.0027853 0.0 498.08 656.72 1045.0 0.0 643.18 733.31 1230.7 723.5 781.22 507.22 True False 490.9772878633148 655.1994051887564 959.0841338166531 0.0 605.3494169405329 701.9480407291012 1294.4196241386517 757.116451266605 693.2307769886978 594.8923011718332 0.8253213008408008 1.1013748268352588 1.6121979254520962 0.0 1.0175781662463963 1.1799581862908413 2.1758890165310136 1.2726949899590545 1.165304670480951 1.0 9.21648469747416 -6.908524676016154 4.120174668725012 1.4544545388296755 0.9127605139314232 0.1880776571801811 0.4725526277128928 0.3557796443148656 11.281660279591456 0.1763519064394437 0.15373696288463048 1.234455173130052e-07 6.908524676016154 -0.5416940248982522 S(ph)GAPVGGGRWQLSDR ddPTM_PC-9_Lapatinib_30min_R1 1 SGAPVGGGRWQLSDR 15 1 P27987-2;P27987 P27987-2 ITPKB Inositol-trisphosphate 3-kinase B 1 S(1)GAPVGGGRWQLSDR 75.669 0.0069524 7284200.0 36337.0 31058.0 31979.0 29419.0 34284.0 29656.0 31391.0 22249.0 31462.0 27080.0 True False 35818.82771661032 30986.087109197837 29349.81006250981 31582.57139890709 32267.4825249374 28387.682011512497 33016.27238265737 23282.76976396779 27918.418250452385 31760.741918168125 1.127770497581508 0.9756096752725049 0.9240908206152707 0.9943902280456769 1.0159549360677687 0.8937978238875417 1.0395308921852056 0.7330675657374781 0.8790228616946189 1.0 14.954956993200351 -7.741033748099443 24.999886405083814 0.8545338085340667 0.9891260867343153 0.304849865468932 0.08516126216893244 250.85465002480126 307334.37553871673 0.038582565158157514 0.022242449535049797 1.815374588398136e-08 7.741033748099443 0.13459227820024866 S(ph)GAQASSTPLSPTR ddPTM_PC-9_AZD4547_30min_R2 1 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 S(0.917)GAQAS(0.016)S(0.051)T(0.016)PLSPTR 163.62 0.00055809 77400000.0 106730.0 80642.0 119760.0 168170.0 148710.0 124410.0 102480.0 113190.0 115210.0 131830.0 True False 140667.91987808893 106707.94945973963 118171.90415020614 129401.00470059967 128064.1834214494 116630.62303289688 111600.52146993438 95699.0863474424 121299.76539412337 127214.67182592902 1.1057523307576371 0.8388022224806801 0.928917258159528 1.0171861691995894 1.006677780033759 0.9168016657110545 0.8772614028564263 0.7522645381531922 0.9535045262711587 1.0 16.956905542463602 -6.9900376174579835 4.285828109565834 0.8768788755708057 0.9708343574111532 0.1554988179123863 0.08802046221176552 0.3454121017274968 15.316947137011134 0.03270632964432144 0.027236247845603394 1.023204361142937e-07 6.9900376174579835 0.09395548184034752 S(ph)GAQASSTPLSPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 S(0.999)GAQASSTPLSPTR 101.01 0.0018159000000000003 5616700.0 3847.7 1749.0 1802.5 9787.8 8128.8 3169.7 9122.1 4635.5 2875.6 3532.7 True False 4499.039614460936 1922.6291612616826 1845.4784360193157 9239.421298475745 6536.019993079056 3003.4753520620557 8257.988649715193 4513.823036718236 2917.6502098992783 4173.150545162187 1.0780918554871073 0.4607140673346978 0.44222666209795036 2.214015813349159 1.5662075744322417 0.7197141151650754 1.9788379451799172 1.0816343642217703 0.6991480844805913 1.0 12.0269212509958 -5.690088851784064 24.99999982284995 1.3386100444629656 0.6403772159913227 0.27158031680475914 0.4963687723411102 59.264091695190125 20763.55259005516 0.13575893315434787 0.23514133207683996 2.0413202706940083e-06 5.690088851784064 -0.6982328284716429 S(ph)GAQASSTPLSPTR ddPTM_PC-9_Lapatinib_30min_R1 1 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 S(1)GAQASSTPLSPTR 101.53 0.0076560000000000005 0.0 1507.7 1181.8 973.27 3361.5 2759.9 3170.8 3075.7 874.59 2438.3 970.3 True False 1486.1999215216815 1179.063614709575 893.2514975308453 3608.7159236352754 2597.568108172169 3035.192275495814 3234.9446964843187 915.2266442477677 2163.6729775627123 1138.0150621565197 1.305958041280541 1.036070306903732 0.7849206282368079 3.171061652555651 2.282542819116841 2.6670932366608358 2.842620281628041 0.8042306949026038 1.9012691918704379 1.0 10.152303937170124 -5.732018406075938 24.999980219925753 2.150123108402614 1.0416910692847368 0.3100008065801094 0.716840447004577 253.17224130605763 215127.03051330653 0.19999337371525128 0.34633351567642634 1.8534530695250048e-06 5.732018406075938 -1.108432039117877 S(ph)GASEANLIVAK ddPTM_PC-9_AZD4547_30min_R2 2 SGASEANLIVAK 12 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(0.974)GAS(0.026)EANLIVAK;S(1)GASEANLIVAK 163.99 0.00015419999999999998 25187000.0 39663.0 76419.0 112359.0 139551.0 131732.0 144554.0 106302.0 153257.0 110284.0 118632.0 True False 52275.008958349616 101119.94729500568 110869.04624593358 107379.67299145751 113443.2856598374 135515.0155284734 115762.67206573935 129574.65214550744 116113.38709075183 114478.72978877068 0.4566351238767616 0.8833077330748356 0.9684685220608451 0.9379879842271842 0.990955139606774 1.1837571553992396 1.0112155531367069 1.1318666129908224 1.0142791355651597 1.0 16.804720044122696 -4.5673418635795136 1.2566784652539147 1.0470338775466939 4.983674244547258e-30 0.8612836923085087 0.06942910867083198 0.797677812860214 0.7758229522347183 0.0211790149557247 1.2293460307679975 2.7080590898393426e-05 4.5673418635795136 -1.0470338775466939 down S(ph)GASEANLIVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGASEANLIVAK 12 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(0.999)GAS(0.001)EANLIVAK;S(1)GASEANLIVAK 149.35 5.7271e-05 17407300.0 50198.0 85421.0 94240.0 97941.0 116613.0 78248.0 99880.0 78379.0 67140.0 57155.0 True False 58695.52994430703 93901.03235227783 96487.03900719016 92453.68329900636 93763.51976342475 74144.53713226854 90418.64333142075 76321.63429941499 68121.79548359894 67516.749061269 0.8693476916526738 1.3907813047554474 1.4290830104931693 1.3693444157850074 1.3887445865963977 1.0981650947824082 1.3392031546034469 1.1304103849869294 1.008961427064281 1.0 16.04295781934546 -8.008292483803102 2.835399285896951 1.005081861701216 1.2823038360402512 0.2999357442193793 0.16170981340631954 0.3374957850979518 5.235542123709505 0.1235927137114767 0.04403097377112242 9.810869889577194e-09 8.008292483803102 0.27722197433903517 S(ph)GASEANLIVAK ddPTM_PC-9_Lapatinib_30min_R1 2 SGASEANLIVAK 12 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(1)GASEANLIVAK;S(0.999)GAS(0.001)EANLIVAK 168.5 0.0007571 27113000.0 50840.0 67635.0 66234.0 54012.0 63981.0 49327.0 48679.0 43670.0 52067.0 32907.0 True False 50115.01227708582 67478.39531298212 60788.49619063375 57984.22265875008 60217.76337148578 47217.39919685317 51199.3604318237 45699.06762517295 46202.66617018322 38594.93110417868 1.2984868956446942 1.7483745502962234 1.5750383392717644 1.5023792244176883 1.5602505730335658 1.223409340190296 1.3265825062265841 1.184069159284627 1.1971174671997498 1.0 15.236123761989333 -7.352458468925103 0.6222287989486559 1.0474870706533963 1.5806562966168873 0.6703714924224987 0.12421237667812626 0.4431791784953096 0.3456314609347907 0.10913208624118315 0.07411345898228473 4.441621340417155e-08 7.352458468925103 0.533169225963491 S(ph)GCCDDSALAR ddPTM_PC-9_AZD4547_30min_R2 1 SGCCDDSALAR 11 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 S(1)GCCDDSALAR 90.434 0.008739499999999999 7607400.0 12301.0 9536.0 19702.0 24250.0 23005.0 25939.0 13368.0 25086.0 16797.0 17503.0 True False 16212.462123305311 12618.325513356289 19440.738606941886 18659.537158765193 19811.152845205088 24317.030229485645 14557.726102752531 21209.535118932192 17684.85512824485 16890.225297498564 0.9598724610089346 0.7470785789473784 1.1510052864612204 1.104753597427067 1.1729359731003182 1.4397102348354696 0.8619024226342632 1.2557283722007733 1.047046727722689 1.0 14.043900951822323 -5.273794821283952 24.425634250920993 1.1405099604782463 0.8534755247642721 0.34002313431329567 0.15296320566603128 498.24450530001917 984987.1407153456 0.03835313242031102 0.08080696822588798 5.323597086588221e-06 5.273794821283952 -0.28703443571397413 S(ph)GCCDDSALAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGCCDDSALAR 11 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 S(0.999)GCCDDS(0.001)ALAR;S(1)GCCDDSALAR 81.709 0.014755 11345000.0 28588.0 32099.0 41628.0 47371.0 55971.0 48951.0 50086.0 41792.0 40017.0 33519.0 True False 33427.38376126237 35285.57658509934 42620.56939506912 44716.956448854166 45003.88434118537 46383.92338668949 45341.491488761916 40695.004282284244 40602.17292027381 39595.72936374201 0.8442168965795583 0.8911460188282453 1.0763930878388357 1.1293378646486478 1.1365842999825035 1.1714375295524537 1.1451106525210601 1.0277624616645866 1.0254179825123617 1.0 15.273057214955308 -5.237775300703098 3.3091397028047127 1.1001399187844163 0.8529481465287433 0.7225658718862755 0.05503771893008905 0.12670483967851678 2.8696820745786003 0.01569815021500592 0.046184619187176895 5.7839522547603805e-06 5.237775300703098 -0.24719177225567301 S(ph)GCCDDSALAR ddPTM_PC-9_Lapatinib_30min_R1 1 SGCCDDSALAR 11 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 S(0.891)GCCDDS(0.109)ALAR 104.59 0.0026634000000000002 4787500.0 9988.5 9162.6 14135.0 9697.6 14340.0 10692.0 13523.0 13248.0 12891.0 11418.0 True False 9846.062158333441 9141.384562648465 12972.87486267788 10410.793854245261 13496.549393524738 10234.728084269349 14223.15477145283 13863.550444201763 11439.079831752006 13391.586086471338 0.7352424197369934 0.6826214985753943 0.9687332612365869 0.7774130552588255 1.007838004130029 0.7642655633307573 1.06209635510028 1.0352433501665064 0.8541990289938975 1.0 13.709039221733171 -3.4070102101738904 0.34866885516641627 0.9861290364629324 6.747235376496961e-07 0.40614868728482467 0.10327559335318034 16.107405021994417 0.7365863700066351 0.08861343144931166 8.091986403993245 0.00039173266744513307 3.4070102101738904 -0.9861283617393948 S(ph)GCSDLEEAVDSGADKK ddPTM_PC-9_AZD4547_30min_R2 1 SGCSDLEEAVDSGADKK 17 1 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 S(0.632)GCS(0.368)DLEEAVDSGADKK 127.59 1.5602e-05 4499700.0 21730.0 16400.0 19885.0 24269.0 23421.0 19644.0 19469.0 22299.0 26070.0 20499.0 True False 28639.68798792168 21700.979280520467 19621.31190737182 18674.15700231227 20169.398425887768 18415.65757461798 21201.703283549446 18853.20193004342 27448.006977040146 19781.33624940999 1.4478136171804827 1.097043142430165 0.9919103370965172 0.9440290972693646 1.0196175916320795 0.9309612526892493 1.071803391653171 0.95308030217654 1.3875709219521926 1.0 14.271852264457559 -4.765960696173822 3.426590692133123 1.029548504711303 1.508905924158099 0.4901416724002009 0.12463433864858448 0.260097771911673 4.828957193299925 0.030476939003808896 0.33617995170892057 1.714112428356773e-05 4.765960696173822 0.479357419446796 S(ph)GDEEFKGEDELCDSGR ddPTM_PC-9_AZD4547_30min_R2 1 SGDEEFKGEDELCDSGR 17 1 O43823;M0QYL4 O43823 AKAP8 A-kinase anchor protein 8 1 S(1)GDEEFKGEDELCDSGR 127.22 0.00016794 10281000.0 33121.0 45481.0 30044.0 21977.0 23649.0 40443.0 38674.0 40096.0 35249.0 28332.0 True False 43652.78904040284 60181.84382057021 29645.596929599124 16910.542191265282 20365.74456145425 37914.092816650154 42115.91107853469 33900.08451441861 37112.190177740245 27340.105303589648 1.596657677637818 2.2012294083106028 1.0843263623314126 0.6185251301517479 0.7449036620491841 1.3867573806188735 1.5404443622609252 1.2399397931348737 1.3574267460069938 1.0 14.738731179211564 -5.273885022288237 24.682587281136914 1.1231264150693487 1.8989435352214372 0.5153650541067396 0.30154463094415085 485.1742747930798 962213.5324427201 0.08755820037202712 0.1843532992971728 5.322491514309417e-06 5.273885022288237 0.7758171201520885 S(ph)GDEEFKGEDELCDSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGDEEFKGEDELCDSGR 17 1 O43823;M0QYL4 O43823 AKAP8 A-kinase anchor protein 8 1 S(1)GDEEFKGEDELCDSGR 70.907 0.006646899999999999 5855500.0 20544.0 24179.0 20602.0 21354.0 24034.0 21486.0 22825.0 22402.0 18316.0 16252.0 True False 24021.69343750434 26579.33132655587 21093.2298135201 20157.60461060208 19324.710229512588 20359.23633605872 20662.850761310372 21813.971236881018 18583.836849532323 19198.358949238795 1.2512368114909522 1.3844585048562044 1.0986996268426599 1.0499649821060002 1.0065813583654661 1.0604675321411237 1.0762821351524758 1.1362414513947783 0.9679909047783046 1.0 14.228695376069886 -5.370625765885169 4.716930428404969 1.050685157828887 1.3162780479693776 0.8011757113007153 0.053838226920919774 0.08481359211730152 2.938246919756022 0.013815413716364081 0.03013702893028186 4.259653118515507e-06 5.370625765885169 0.2655928901404907 S(ph)GDEEFKGEDELCDSGR ddPTM_PC-9_Lapatinib_30min_R1 4 SGDEEFKGEDELCDSGR 17 1 O43823;M0QYL4 O43823 AKAP8 A-kinase anchor protein 8 1 S(1)GDEEFKGEDELCDSGR;S(0.999)GDEEFKGEDELCDS(0.001)GR;S(1)GDEEFKGEDELCDSGR;S(1)GDEEFKGEDELCDSGR 134.82 0.00016536 45657800.0 98216.0 135869.0 100877.0 103604.0 129893.0 108017.0 123321.0 126416.0 108927.0 117951.0 True False 96815.42182939142 135554.4036782664 92583.2824564808 111223.38377281267 122252.94911946356 103397.36470992531 129705.95796571285 132289.74886429755 96658.49420783897 138338.6731901719 0.6998435043272452 0.9798735274258558 0.6692509066442186 0.803993425756771 0.8837221458052041 0.7474219777125277 0.9375972385350856 0.956274524061981 0.69870913157425 1.0 17.077844999112294 -7.266689025661582 24.945385192317268 0.8945014329750616 0.8040525667750615 0.1618076999427721 0.11164051103152535 902.2369385625414 4287244.3556451695 0.04378937737831767 0.03049510270930505 5.4114166596861506e-08 7.266689025661582 -0.09044886620000003 S(ph)GDEMIFDPTMSK ddPTM_PC-9_AZD4547_30min_R2 4 SGDEMIFDPTMSK 13 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(0.928)GDEMIFDPT(0.055)MS(0.017)K;S(1)GDEMIFDPTMSK 86.944 0.0043897 93637000.0 393715.0 279603.0 470279.0 533863.0 403510.0 436674.0 406305.0 487417.0 398681.0 411166.0 True False 518908.18021926295 369979.20181532664 464042.7931851601 410789.1334511289 347489.6015895974 409368.70574927476 442465.3578829202 412097.9023784009 419754.4637366072 396771.2034891895 1.307827220463597 0.932474934072193 1.1695475606707015 1.0353300084246697 0.8757934006646356 1.031750041709941 1.115164996834191 1.0386285565949067 1.057925726578199 1.0 18.597947797311555 -4.748235860778117 24.996794746207947 1.032376886940507 1.307827885047355 0.5309201136818902 0.07868779098105191 543.2486774452632 1028413.686253872 0.0199015905825507 0.37024163643411895 1.7855176155985284e-05 4.748235860778117 0.27545099810684803 S(ph)GDEMIFDPTMSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SGDEMIFDPTMSK 13 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 S(1)GDEMIFDPTMSK;S(0.999)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(0.999)GDEMIFDPT(0.001)MSK 91.712 0.0029757 43369600.0 189479.0 237429.0 220917.0 278146.0 276359.0 234861.0 243059.0 304587.0 246721.0 180306.0 True False 221554.05231916282 260999.38200640393 226184.49911238818 262562.3813814993 222208.43780968132 222544.47571083874 220034.69192522866 296591.91398660303 250328.82787472513 212994.05049848967 1.0401889245292972 1.22538343862452 1.0619287185864004 1.2327216688306564 1.0432612426949315 1.0448389294912104 1.033055577891782 1.3924891953200644 1.1752855410226597 1.0 17.700453607065384 S(ph)GDEMIFDPTMSK ddPTM_PC-9_Lapatinib_30min_R1 3 SGDEMIFDPTMSK 13 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 S(1)GDEMIFDPTMSK;S(0.991)GDEMIFDPT(0.003)MS(0.006)K;S(0.907)GDEMIFDPT(0.084)MS(0.008)K 110.51 0.0005886 17242500.0 157545.0 146322.0 178810.0 156244.0 165300.0 166774.0 148414.0 139063.0 168257.0 134751.0 True False 155298.37940978556 145983.2003989971 164108.93202656027 167734.7049747047 155577.37899230403 159641.46478918212 156098.1507247209 145524.37465444088 149306.12483524156 158042.53080557895 0.9826366271040724 0.9236956637867498 1.0383846119779245 1.0613263665149029 0.984401972046958 1.0101171119916459 0.9876971086773472 0.9207924848625862 0.944721171409962 1.0 17.269953328569564 -7.591898345336498 7.0183784422858455 0.949859742280662 1.0003183685907857 0.20754456276321998 0.03885036212295466 0.33493877662812727 27.88627646008827 0.019553905728466957 0.011211510568204016 2.5591848413945587e-08 7.591898345336498 0.050458626310123766 S(ph)GDETPGSEVPGDK ddPTM_PC-9_AZD4547_30min_R2 3 SGDETPGSEVPGDK 14 0 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 S(1)GDETPGSEVPGDK;S(1)GDETPGSEVPGDK;S(1)GDETPGSEVPGDK 207.31 7.210600000000001e-11 132902000.0 225438.7 337485.3 222038.9 113081.8 157958.0 317459.9 305110.0 298010.8 321991.4 210942.1 True False 297123.5171837404 446570.82334025844 219094.51910836 87012.53810639394 136028.25825354952 297609.082267994 332264.19892360986 251960.07846691727 339011.20804552885 203557.08128477787 1.4596569930576986 2.1938358544034267 1.0763296355278602 0.4274601382433007 0.6682560851972768 1.4620423931685123 1.6322900526303468 1.2377858676133366 1.6654355913624526 1.0 17.635073884844886 S(ph)GDETPGSEVPGDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SGDETPGSEVPGDK 14 0 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 S(0.997)GDET(0.003)PGSEVPGDK;S(0.991)GDET(0.009)PGSEVPGDK;S(0.997)GDET(0.003)PGSEVPGDK 207.64 6.790699999999999e-11 143693000.0 237045.0 523773.0 300792.0 218290.0 273949.0 157332.0 278595.0 117746.3 174816.0 195561.0 True False 277172.0366478399 575769.7219448347 307964.0220400117 206059.9190057291 220270.66000935138 149081.23295284313 252204.46474686748 114655.58438751721 177372.35328062082 231014.66123997627 1.1998027967580625 2.4923514328241247 1.3330929750822222 0.8919776688617855 0.9534921239502453 0.6453323445042247 1.0917249294618552 0.4963130208797175 0.76779695422174 1.0 17.817624888965597 -5.574586381960218 3.636426215845395 0.8236545024780384 1.8660094894480568 0.5920441442229631 0.33540828737200895 0.13213260169859578 3.5904058779151997 0.08679175498917291 0.16739910713408557 2.663260316773736e-06 5.574586381960218 1.0423549869700184 S(ph)GDETPGSEVPGDK ddPTM_PC-9_Lapatinib_30min_R1 3 SGDETPGSEVPGDK 14 0 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 S(1)GDETPGSEVPGDK;S(1)GDETPGSEVPGDK;S(0.995)GDET(0.005)PGSEVPGDK 157.86 0.00015407 205873000.0 74644.8 142470.0 107563.9 103919.2 134407.0 127080.9 147146.0 141232.0 126655.8 124924.0 True False 73580.35146382012 142140.11946833055 98720.41135066147 111561.76463228896 126501.44451432895 121645.94614704676 154764.49988909243 147794.1543127643 112390.4900592986 146516.94694923295 0.5021968652494183 0.9701275001149257 0.6737815208835014 0.7614256709221787 0.8633912127459274 0.8302517127195954 1.056290778040285 1.0087171306127058 0.7670818454758075 1.0 17.16070801871296 -6.606037275918548 1.424571591675808 0.9530276637804668 0.7364337803627463 0.36086144116924357 0.13173959540808158 0.47483646286699727 1.9984945235338967 0.05486949613615173 0.05673383755456894 2.477209427209405e-07 6.606037275918548 -0.21659388341772046 S(ph)GDETPGSEVPGDKAAEEQGDDQDSEK ddPTM_PC-9_AZD4547_30min_R2 1 SGDETPGSEVPGDKAAEEQGDDQDSEK 27 1 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 S(0.638)GDET(0.349)PGS(0.013)EVPGDKAAEEQGDDQDSEK 96.022 1.3474e-09 11517000.0 11180.0 9055.5 9827.5 9824.2 9738.5 10784.0 8854.4 9623.2 10276.0 9190.7 True False 14735.007441553804 11982.51328504591 9697.180928825575 7559.382472376955 8386.477373746126 10109.674775233172 9642.424446754338 8136.155559136905 10819.168381130214 8868.936390431367 1.6614176483948289 1.3510654217763653 1.0933871325639224 0.8523437467127084 0.9456012541474801 1.139897089141425 1.087213169908117 0.9173766955770419 1.2198946868987512 1.0 13.114545383973438 -4.9921498828420106 2.0315314271180265 1.0217548575691142 1.7104693338943122 0.7937566159495132 0.10313367304885582 0.2056576929403327 1.290354989182567 0.029027345646882266 0.2260963114536154 1.0182399144872034e-05 4.9921498828420106 0.688714476325198 S(ph)GDETPGSEVPGDKAAEEQGDDQDSEK ddPTM_PC-9_Lapatinib_30min_R1 1 SGDETPGSEVPGDKAAEEQGDDQDSEK 27 1 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 S(0.888)GDET(0.107)PGS(0.005)EVPGDKAAEEQGDDQDSEK 53.096000000000004 0.0039756 23033000.0 10341.0 7310.2 7239.4 6552.5 6586.3 6777.7 5768.7 7175.8 7821.0 5460.0 True False 10193.535443692852 7293.273681037352 6644.204476892134 7034.3927084992265 6198.906783164017 6487.833570590384 6067.375059534119 7509.2138645458235 6940.116621218873 6403.753725007311 1.5918062875975472 1.1389060220346037 1.0375484071078247 1.0984795809728294 0.9680114272597108 1.01312977500286 0.9474716424275345 1.1726268977555427 1.0837575770781143 1.0 12.644702110545207 -4.732879897810832 2.720094258979871 1.041938580295504 1.7409155693098664 0.8737213622377238 0.06264701407822358 0.1874407126007537 1.6577980462634179 0.01687841002772515 0.31569044422807824 1.8497800966323695e-05 4.732879897810832 0.6989769890143624 S(ph)GDVLAK ddPTM_PC-9_Lapatinib_30min_R1 1 SGDVLAK 7 0 P85299;P85299-5;P85299-2;P85299-4;P85299-3;B1AHG4 P85299 PRR5 Proline-rich protein 5 1 S(1)GDVLAK 74.464 0.034143 6906400.0 54135.0 70093.0 60765.0 62672.0 64693.0 63281.0 62225.0 59252.0 57310.0 62135.0 True False 53363.02497285686 69930.703965001 55769.13625968319 67281.10794766333 60887.88493133167 60574.61914521594 65446.70603073667 62005.06423006064 50855.14429894559 72874.95196031686 0.7322546847360534 0.9595986286629854 0.765271670985822 0.9232405118332073 0.8355118362820658 0.8312131605685461 0.8980685992956106 0.8508419225281235 0.6978412051185724 1.0 16.153135406828135 -4.717289782720412 23.93398561864402 0.8559034328513324 0.7322519365610166 0.17096554211497517 0.08489848755687177 12507.083573697728 6779360.356289184 0.019565247534474233 10.23546918319413 1.9173889371790844e-05 4.717289782720412 -0.1236514962903158 S(ph)GEGEVSGLMR ddPTM_PC-9_AZD4547_30min_R2 3 SGEGEVSGLMR 11 0 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 S(0.999)GEGEVS(0.001)GLMR;S(1)GEGEVSGLMR;S(1)GEGEVSGLMR 135.1 6.8179e-05 43413400.0 70561.7 78866.6 99258.90000000001 116482.6 104930.7 106913.9 97668.40000000001 104801.7 94798.0 99726.70000000001 True False 92998.8528254638 104358.68612957894 97942.66213138682 89629.3362082303 90362.88354072414 100228.5569317322 106360.69839123826 88607.0053684843 99808.82874604741 96235.29858744505 0.9663694526905797 1.0844117248179213 1.0177415518941872 0.9313561398345724 0.9389785750871351 1.0414947363690947 1.1052150297491172 0.9207328981056858 1.037133257869567 1.0 16.55427854336171 S(ph)GEGEVSGLMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGEGEVSGLMR 11 0 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 S(0.998)GEGEVS(0.002)GLMR 65.842 0.03847 7644100.0 26812.0 35173.0 28857.0 31529.0 39668.0 28762.0 38181.0 30498.0 26543.0 27346.0 True False 31350.742038861314 38664.74298974109 29545.060320781915 29762.532348397177 31895.340159120657 27253.67008739275 34564.219273497976 29697.45981530206 26931.141160577467 32303.613329183114 0.9705026406609141 1.1969169701152695 0.9146054349929604 0.9213375619968085 0.9873613776297395 0.8436724960043946 1.0699799716297567 0.9193231578361343 0.8336881972348229 1.0 14.97940792652858 -5.286901056201649 24.8012098823518 0.9361278171473683 1.0837098355176074 0.3311968444165718 0.08382057729831831 639.487529402207 622898.3642497086 0.020799991701429536 0.04332770842124691 5.1653403601713025e-06 5.286901056201649 0.1475820183702391 S(ph)GEGEVSGLMR ddPTM_PC-9_Lapatinib_30min_R1 4 SGEGEVSGLMR 11 0 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 S(1)GEGEVSGLMR;S(1)GEGEVSGLMR;S(1)GEGEVSGLMR;S(1)GEGEVSGLMR 168.82 0.00020016 67281000.0 155741.9 146520.2 159163.30000000002 122701.90000000001 188713.6 183173.1 175986.9 176573.9 172537.30000000002 167267.09999999998 True False 153520.99194643335 146180.94147907424 146077.50786210518 131725.80704753892 177613.83707321264 175339.21351035137 185098.64057148513 184778.16800871346 153104.33237568417 196178.99536559876 0.7825557046019731 0.7451406365225377 0.7446133954854619 0.6714572413935294 0.9053662281337095 0.8937715945766241 0.9435191582388098 0.941885585989271 0.7804318300761978 1.0 17.58181105674781 -6.276629014323568 24.426302798343304 0.9087049943495578 0.737218215966548 0.6844054338120322 0.05816645434200347 341.91216421976304 549824.2412754816 0.017578806758433804 0.020011347066991824 5.288968563542126e-07 6.276629014323568 -0.17148677838300974 S(ph)GEQIFTQDVRPEQLLEGK ddPTM_PC-9_AZD4547_30min_R2 1 SGEQIFTQDVRPEQLLEGK 19 1 Q8WXE0-2;Q8WXE0 Q8WXE0-2 CASKIN2 Caskin-2 1 S(1)GEQIFTQDVRPEQLLEGK 74.251 0.0020800000000000003 7680200.0 15239.0 16042.0 22825.0 28093.0 25990.0 22660.0 21148.0 32554.0 23731.0 27040.0 True False 20084.685009108984 21227.262781592024 22522.325586409945 21616.592882523328 22381.737120055648 21243.066617839737 23030.131030895474 27523.52731649998 24985.372212203292 26093.337830335455 0.7697246377486837 0.8135127410535322 0.8631446744320329 0.828433411742074 0.8577567678610747 0.8141184066203705 0.8826057892877632 1.0548105227266795 0.9575383714672153 1.0 14.671393883431312 -7.59837490713521 4.61861976475162 1.0033785341661576 0.8286492322521851 0.8540683576182098 0.03311915382309411 0.07424117116400673 2.971995879201752 0.01615804825306936 0.009065600679708586 2.5213033036120082e-08 7.59837490713521 -0.1747293019139725 S(ph)GEQIFTQDVRPEQLLEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGEQIFTQDVRPEQLLEGK 19 1 Q8WXE0-2;Q8WXE0 Q8WXE0-2 CASKIN2 Caskin-2 1 S(1)GEQIFTQDVRPEQLLEGK;S(1)GEQIFTQDVRPEQLLEGK 85.397 0.00061205 9776600.0 38536.0 39872.0 34808.0 41111.0 39793.0 35856.0 34309.0 37195.0 26443.0 29036.0 True False 45059.383679306244 43830.22865513196 35637.95473007509 38807.68395366031 31995.847306440668 33975.648239119495 31059.00314435039 36218.67066136011 26829.67884975888 34299.99695115046 1.3136847721438325 1.277849345513188 1.0390075188878334 1.131419457818892 0.9328236195475081 0.9905437684880002 0.9055103762424281 1.055938014016217 0.7822064499880074 1.0 15.065920827709627 -5.026173168956379 0.6509191406180063 0.9345642018776631 1.5177719645097074 0.7317981004720684 0.08024363470887294 1.2366761583276404 0.4910799563347624 0.03633922139782249 0.5119745234155495 9.41514105855967e-06 5.026173168956379 0.5832077626320443 S(ph)GEQIFTQDVRPEQLLEGK ddPTM_PC-9_Lapatinib_30min_R1 2 SGEQIFTQDVRPEQLLEGK 19 1 Q8WXE0-2;Q8WXE0 Q8WXE0-2 CASKIN2 Caskin-2 1 S(1)GEQIFTQDVRPEQLLEGK;S(1)GEQIFTQDVRPEQLLEGK 75.057 0.0019612 13087900.0 29187.1 35254.7 33543.0 40147.0 35403.0 31175.3 28413.6 28196.5 32392.8 34064.0 True False 28770.886601741408 35173.06990819229 30785.22401972439 43099.54430646598 33320.665144976025 29842.005092173804 29884.71717918744 29506.612326383984 28744.381752693862 39951.917012573125 0.7201378244925525 0.8803850362705523 0.7705568673972786 1.0787853882681593 0.834019181970412 0.7469480146042137 0.7480171019023324 0.7385531041501229 0.7194744057875325 1.0 15.285977109190288 -6.541343503688372 12.668752992948658 0.7736690542771057 0.8695708567751558 0.06978114479259145 0.11523439136653815 1.873607315462887 1278.1655435360024 0.0370179185189121 0.03718077056677004 2.8751234464180046e-07 6.541343503688372 0.09590180249805003 S(ph)GEQITSSPVSPK ddPTM_PC-9_AZD4547_30min_R2 1 SGEQITSSPVSPK 13 0 A0A087WWN8;A0A087WZV0;O43314-2;O43314 A0A087WWN8 PPIP5K2 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 1 S(1)GEQITSSPVSPK 159.41 0.00026675 4502400.0 32547.0 27456.0 33161.0 42611.0 38368.0 32105.0 28951.0 41746.0 26807.0 33297.0 True False 42896.26898034453 36330.615068656676 32721.26347298749 32787.6922833874 33041.265479888214 30097.469274745996 31527.582914481496 35295.11492764663 28223.963292424833 32131.282164818018 1.33503134921001 1.1306929764675464 1.0183615862306132 1.0204290048309406 1.0283207906364402 0.9367030272978358 0.9812114796029665 1.098465811186733 0.8783951772496809 1.0 14.971690930726576 -4.275500589007406 1.0418267495815492 0.9906566371686695 1.9673080189210705 0.7937368834076817 0.054012989293012376 1.9012269852905306 0.8121551001072811 0.016397174423083447 2.6594510190187646 5.302728734516189e-05 4.275500589007406 0.9766513817524011 S(ph)GEQITSSPVSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGEQITSSPVSPK 13 0 A0A087WWN8;A0A087WZV0;O43314-2;O43314 A0A087WWN8 PPIP5K2 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 1 S(1)GEQITSSPVSPK;S(0.999)GEQITSSPVSPK 122.75 0.00017713 14406900.0 95166.0 108076.0 81289.0 102048.0 92853.0 64536.0 59659.0 45692.0 53414.0 45900.0 True False 111275.72418582258 118805.0710305989 83227.23805024909 96330.5814040798 74659.12120083756 61151.61855086499 54007.6676262438 44492.633414675794 54195.07870063991 54221.30665579992 2.052250877910551 2.191114127602652 1.5349544889904727 1.7766185904665128 1.3769332722794398 1.1278152874304395 0.9960598693994537 0.8205747179262514 0.9995162795443772 1.0 15.72657226002733 -6.132378584935511 0.6881742037374879 0.8888020277500933 2.190362972199585 0.9088342615395838 0.13848693854892977 0.23206302216357028 0.22549262510356466 0.08266989050844008 0.1804498081866599 7.372612615669304e-07 6.132378584935511 1.3015609444494918 up S(ph)GEQITSSPVSPK ddPTM_PC-9_Lapatinib_30min_R1 3 SGEQITSSPVSPK 13 0 A0A087WWN8;A0A087WZV0;O43314-2;O43314 A0A087WWN8 PPIP5K2 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 1 S(1)GEQITSSPVSPK;S(0.968)GEQIT(0.013)S(0.013)S(0.007)PVSPK;S(1)GEQITSSPVSPK 167.69 0.00027935 19139000.0 153104.0 140094.0 135666.0 113009.0 116141.0 92183.7 79394.0 76962.0 92980.0 64691.0 True False 150920.70888416475 139769.62095034955 124512.0651659041 121320.05884697278 109309.81472199147 88241.21804170033 83504.63284217441 80537.93548359437 82507.6132771936 75872.75315466088 1.9891292013158435 1.8421582865912316 1.6410642818258572 1.5989937599822033 1.440699199344614 1.1630158966530089 1.1005878839266123 1.0614869256085102 1.0874472039917684 1.0 16.211294268537223 -6.036570912264502 0.5726617095507976 0.9978219517874332 2.0741361167531602 0.9799112664628602 0.04826197085834785 0.16538164682796208 0.10120500228470085 0.03679151023055939 0.10020812623331199 9.192403675820836e-07 6.036570912264502 1.076314164965727 S(ph)GERELLLVGRTGIPS(ph)T(ph)PPAPQSR ddPTM_PC-9_Lapatinib_30min_R1 1 SGERELLLVGRTGIPSTPPAPQSR 24 2 A0PJK1-3 A0PJK1-3 3 S(1)GERELLLVGRT(0.024)GIPS(0.893)T(0.892)PPAPQS(0.19)R 62.302 0.011211 0.0 5707.3 1952.9 35907.0 5560.3 10282.0 17066.0 7111.9 8098.9 33532.0 6369.3 True False 5625.912855409365 1948.378180035818 32954.865065028294 5969.223010617051 9677.232975189776 16336.126962789065 7480.119383206046 8475.204460488052 29755.273052386034 7470.225018441225 0.7531115651163205 0.26081920895635574 4.411495635496242 0.799068702198561 1.2954406261257545 2.186831979285926 1.0013245069245431 1.1345313480605876 3.983182966902772 1.0 12.866935985253562 S(ph)GGDGGDEVEGSGVGAGEGETVQHFPLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGGDGGDEVEGSGVGAGEGETVQHFPLAR 29 0 Q96DT7-3;Q96DT7-2;Q96DT7 Q96DT7-3 ZBTB10 Zinc finger and BTB domain-containing protein 10 1 S(1)GGDGGDEVEGSGVGAGEGETVQHFPLAR 188.93 4.784499999999999e-62 0.0 632.83 818.25 725.0 876.3 820.5 717.7 1083.3 638.13 907.6 893.55 True False 739.9556200377666 899.4804523741398 742.286749577811 827.2037520029315 659.7289150085332 680.062548561358 980.6819815871866 621.3797636546234 920.8719329894925 1055.5435416620924 0.7010185661053916 0.8521490747390574 0.7032270297528255 0.7836756318932995 0.6250134541770803 0.6442771157412511 0.9290777148264046 0.588682265703771 0.872414918610992 1.0 10.043770376416159 -8.521322178021892 23.222358650399674 1.0000000048014839 0.7337462297807887 0.44119231291652217 0.09876243315853306 42.542571650832485 634678.1762272662 0.09084107518612042 0.023455064731166004 3.0107716777044398e-09 8.521322178021892 -0.26625377502069514 S(ph)GGGAGSNGSVLDPAER ddPTM_PC-9_AZD4547_30min_R2 1 SGGGAGSNGSVLDPAER 17 0 Q15149-3;Q15149-2;H0YDN1;E9PMV1 Q15149-3 PLEC Plectin 1 S(1)GGGAGSNGSVLDPAER 166.21 2.4313000000000003e-05 15986000.0 7045.2 5515.4 10974.0 10374.0 11331.0 11479.0 6717.0 10782.0 10525.0 5274.1 True False 9285.427050736575 7298.145190474542 10828.477589715785 7982.434576702275 9757.886237297053 10761.216315365502 7314.799987446799 9115.889645711828 11081.330012786635 5089.455364311101 1.8244441469806332 1.4339737099673737 2.1276299357390096 1.5684260898872746 1.9172751382638094 2.114414125885967 1.4372461223926887 1.7911326444938254 2.1773115627445105 1.0 12.313295562721768 -10.988531611996498 7.137290681236266 0.9998755202708438 1.8107546528145655 0.4716012062731182 0.2605950232860131 0.0004984719490555977 3.731881158611557e-05 0.24366437963838436 0.05908846911548315 1.0267586918893251e-11 10.988531611996498 0.8108791325437217 S(ph)GGGAGSNGSVLDPAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGGGAGSNGSVLDPAER 17 0 Q15149-3;Q15149-2;H0YDN1;E9PMV1 Q15149-3 PLEC Plectin 1 S(0.737)GGGAGS(0.259)NGS(0.004)VLDPAER;S(1)GGGAGSNGSVLDPAER 197.6 2.8595e-12 22633000.0 59347.0 61111.0 47631.0 56104.0 62902.0 55699.0 65974.0 55356.0 56461.0 52182.0 True False 69393.2749433201 67177.6962114708 48766.70368157338 52960.67477162215 50576.80464578517 52778.04638751442 59724.465109603065 53902.96365453021 57286.63531128225 61642.18352751529 1.1257432974019317 1.0898007235821654 0.7911255067693268 0.8591628612244411 0.8204901538442282 0.8562001435908873 0.9688895118866739 0.8744492905652748 0.9293414352480092 1.0 15.911630346342507 -5.180508970038762 6.540952917178871 0.881596388346439 1.1131622651447945 0.673943594067723 0.06125305015378111 0.13362552386658327 8.923393345470085 0.015611339803140696 0.04229373000330987 6.599196039601508e-06 5.180508970038762 0.2315658767983555 S(ph)GGGAGSNGSVLDPAER ddPTM_PC-9_Lapatinib_30min_R1 2 SGGGAGSNGSVLDPAER 17 0 Q15149-3;Q15149-2;H0YDN1;E9PMV1 Q15149-3 PLEC Plectin 1 S(1)GGGAGSNGSVLDPAER;S(1)GGGAGSNGSVLDPAER 149.72 2.9271999999999997e-05 30484000.0 22204.1 16774.8 19713.6 15485.0 15121.4 15893.300000000001 15799.699999999999 16251.0 18451.9 12848.900000000001 True False 21887.46546226675 16735.958981240634 18092.823904696616 16623.81855644571 14231.988981816236 15213.580608091845 16617.73115747416 17006.080787192263 16373.652714878974 15069.815244916937 1.4524043663806305 1.1105616564798755 1.2006002469605155 1.1031202630074006 0.9444036805040923 1.009539955257474 1.102716316517506 1.1284863490896764 1.0865198045743674 1.0 13.879374109233957 -1.6601096806716786 0.9505887412386884 1.0608900925391203 199.9999999955751 0.7414534672004451 0.0674395795127028 500.2268735436453 1.1589017600170164 0.02342273994999028 215974.21345044742 0.021872091765280273 1.6601096806716786 198.93910990303598 S(ph)GGGDLTLGLEPSEEEAPR ddPTM_PC-9_AZD4547_30min_R2 2 SGGGDLTLGLEPSEEEAPR 19 0 B4DTR1;P04626-3;P04626-2;P04626-5;P04626-4;P04626 B4DTR1 ERBB2 Receptor protein-tyrosine kinase;Receptor tyrosine-protein kinase erbB-2 1 S(0.994)GGGDLT(0.005)LGLEPS(0.001)EEEAPR;S(0.976)GGGDLT(0.024)LGLEPSEEEAPR 118.05 5.8318e-05 3517900.0 8876.6 11659.7 10570.5 10622.1 11849.400000000001 9478.9 12975.0 12854.9 11160.5 9614.3 True False 11699.174155250135 15428.470007139289 10430.328263357995 8173.3389548090645 10204.31534553241 8886.18288454726 14129.74986409441 10868.470581215075 11750.421245387668 9277.70628336517 1.2609985483401895 1.6629616778020202 1.12423566178846 0.8809654784463025 1.0998748002864285 0.9577995479852699 1.522978787270826 1.1714609461933634 1.266522229363528 1.0 13.179552458265235 -5.286017850450836 23.686310535634874 1.1323067991040725 1.4619800877283666 0.3281050235308208 0.1911036243474953 408.1929045665106 393375.71964638 0.051255465962209874 0.10679921884826327 5.175855576175709e-06 5.286017850450836 0.3296732886242941 S(ph)GGGDLTLGLEPSEEEAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGGGDLTLGLEPSEEEAPR 19 0 B4DTR1;P04626-3;P04626-2;P04626-5;P04626-4;P04626 B4DTR1 ERBB2 Receptor protein-tyrosine kinase;Receptor tyrosine-protein kinase erbB-2 1 S(1)GGGDLTLGLEPSEEEAPR;S(1)GGGDLTLGLEPSEEEAPR 139.12 3.8296e-05 5468000.0 11451.9 9497.7 9832.0 6612.0199999999995 14775.599999999999 5376.5 5384.179999999999 3622.7 3993.09 3853.1000000000004 True False 13390.480484664917 10440.568887887408 10066.432168067642 6241.569955858071 11880.427247532089 5094.546875212682 4874.151492312469 3527.607963567933 4051.4813870659036 4551.636528877182 2.941904609410484 2.2938054964733605 2.2116072107697216 1.3712803990958762 2.610144103589661 1.119278053704659 1.0708569239633126 0.7750196970227188 0.8901153159664401 1.0 12.152169640434229 -6.116851311742173 0.46200791645351813 0.7322428447913317 3.0111829052091585 0.7241530562171367 0.3991740769616258 0.8761946375128373 0.3294224540071092 0.3474736924567853 0.964589018464984 7.640973407947251e-07 6.116851311742173 2.2789400604178267 up S(ph)GGGDLTLGLEPSEEEAPR ddPTM_PC-9_Lapatinib_30min_R1 2 SGGGDLTLGLEPSEEEAPR 19 0 B4DTR1;P04626-3;P04626-2;P04626-5;P04626-4;P04626 B4DTR1 ERBB2 Receptor protein-tyrosine kinase;Receptor tyrosine-protein kinase erbB-2 1 S(1)GGGDLTLGLEPSEEEAPR;S(1)GGGDLTLGLEPSEEEAPR 221.9 1.2858999999999999e-28 5230100.0 12694.4 17549.6 5638.1 5501.200000000001 5305.6 2813.69 671.86 651.63 1603.25 562.8 True False 12513.375528132145 17508.964979444216 5174.5571816953825 5905.776599465231 4993.535039210939 2693.3550377317447 706.6456233637726 681.9071086922702 1422.6751020290442 660.0792301161384 18.957384139977353 26.52555054090034 7.839297080723081 8.947072305889904 7.5650540289418675 4.0803511379351525 1.0705466724645176 1.0330685735594063 2.1553096009076516 1.0 9.366495393087163 -5.435644120064163 0.7294172533685185 1.4934973077862936 27.78875522323505 0.8278046397451687 3.369610848007564 0.521479116356398 0.37800907864602734 1.5441886991568787 9.804988295241932 3.667379727222128e-06 5.435644120064163 26.295257915448758 S(ph)GGGGYSQNR ddPTM_PC-9_Lapatinib_30min_R1 1 SGGGGYSQNR 10 0 M0R3F1;A0A0A0MRA5;B7Z4B8;Q9BUJ2-3;Q9BUJ2-4;Q9BUJ2-2;Q9BUJ2;Q9BUJ2-5 M0R3F1 HNRNPUL1 Heterogeneous nuclear ribonucleoprotein U-like protein 1 1 S(1)GGGGYSQNR 83.045 0.014081999999999999 1274700.0 5411.9 6643.9 7189.0 5585.4 5398.2 5489.3 4424.3 5726.5 4441.2 4929.2 True False 5334.725313579092 6628.516457749996 6597.948170342503 5996.1689483482 5080.688489269543 5254.5354351832875 4653.368605733843 5992.574095616049 3940.9852880906865 5781.205652253858 0.922770376019974 1.14656299333787 1.141275465225879 1.0371831256358328 0.878828534198362 0.9088995879492294 0.8049131765308648 1.0365613085014174 0.6816891709351761 1.0 12.497154678277845 -6.189605530843912 3.9113654733500236 0.8835011386260666 1.079067810650221 0.3897085728761458 0.10853208625776199 0.22435917615580045 6.688967428249874 0.03131653403147965 0.04069936147825572 6.462409424102944e-07 6.189605530843912 0.19556667202415434 S(ph)GGNEVSIEER ddPTM_PC-9_Lapatinib_30min_R1 2 SGGNEVSIEER 11 0 Q15061 Q15061 WDR43 WD repeat-containing protein 43 1 S(1)GGNEVSIEER;S(1)GGNEVSIEER 130.66 0.00019804 31315000.0 11265.8 18181.2 24899.0 23450.0 32583.0 22140.4 20048.5 24307.6 37070.0 9250.4 True False 11105.147626105305 18139.102548449602 22851.90033291948 25174.591226906792 30666.532000642725 21193.506703793224 21086.513231936107 25437.01983525657 32894.78623559439 10849.319314616785 1.023580125542425 1.6719115755042466 2.1062980699749683 2.320384394345388 2.826585807952682 1.9534411412557648 1.9435793730881554 2.3445728803452632 3.0319677467024837 1.0 13.405316910492743 -4.909347510020607 1.6973147837234632 2.2610120375127702 0.7786129462832959 0.3276365773040226 0.5213358333311675 0.7855698084684548 2.7607402600522444 0.14061426039207145 1.7700802185208229 1.2321185326740151e-05 4.909347510020607 -1.4823990912294742 S(ph)GGSGGCSGAGGASNCGTGSGR ddPTM_PC-9_AZD4547_30min_R2 1 SGGSGGCSGAGGASNCGTGSGR 22 0 E9PL01;A0A087WUC6;E9PI68;Q15005 E9PL01 SPCS2 Signal peptidase complex subunit 2 1 S(0.982)GGS(0.018)GGCSGAGGASNCGTGSGR 159.1 1.9327999999999998e-23 0.0 476.4 0.0 0.0 926.39 0.0 0.0 0.0 0.0 425.23 0.0 True False 627.8852902644215 0.0 0.0 712.8250980828244 0.0 0.0 0.0 0.0 447.70678967574935 0.0 0.0 S(ph)GGSGGCSGAGGASNCGTGSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SGGSGGCSGAGGASNCGTGSGR 22 0 E9PL01;A0A087WUC6;E9PI68;Q15005 E9PL01 SPCS2 Signal peptidase complex subunit 2 1 S(0.723)GGS(0.275)GGCS(0.002)GAGGASNCGTGSGR;S(0.588)GGS(0.412)GGCSGAGGASNCGTGSGR;S(0.965)GGS(0.034)GGCSGAGGASNCGTGSGR 235.21 2.1435999999999997e-51 2292560.0 1034.9 1065.24 584.77 1490.6 2667.87 1176.95 2362.0 515.35 474.98 0.0 True False 1210.088129793285 1170.9899872740955 598.7131345525751 1407.0865145904033 2145.12002496504 1115.2286700979382 2138.2542606008797 501.8226085584601 481.9256839261229 0.0 0.0 S(ph)GHFDVTTVASIK ddPTM_PC-9_AZD4547_30min_R2 2 SGHFDVTTVASIK 13 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;Q8TDM6-5 Q8TDM6-4 DLG5 Disks large homolog 5 1 S(1)GHFDVTTVASIK;S(1)GHFDVTTVASIK 166.03 5.6041999999999996e-05 12526800.0 30732.0 24451.0 45145.0 76316.0 52950.0 44043.0 33114.0 51199.0 39972.0 40397.0 True False 40504.13673468975 32354.307584634505 44546.34780278103 58722.52527044641 45598.80648353008 41288.98424755142 36061.08184968188 43287.370985976646 42084.838315544635 38982.71332588981 1.0390281557900054 0.8299655109729588 1.142720554887497 1.5063734732760812 1.1697186417561727 1.0591613750018252 0.9250531523605473 1.1104247830083176 1.0795769387246472 1.0 15.25054688999059 -6.883947709793429 5.657636490338684 1.0320733299342328 1.1407032420116092 0.09297786253904672 0.16200422081797464 0.6315255403844334 28.861678462605976 0.06530373096121464 0.057585348779715495 1.306328164036361e-07 6.883947709793429 0.10862991207737638 S(ph)GHFDVTTVASIK ddPTM_PC-9_Lapatinib_30min_R1 2 SGHFDVTTVASIK 13 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;Q8TDM6-5 Q8TDM6-4 DLG5 Disks large homolog 5 1 S(1)GHFDVTTVASIK;S(1)GHFDVTTVASIK 135.02 0.00013495 3683800.0 46368.0 37287.0 54420.0 33587.0 46710.0 52053.0 37325.0 37532.0 47565.0 31271.0 True False 45706.78381715022 37200.66424240647 49945.79766727487 36057.10002294748 43962.60963539333 49826.81453146954 39257.50586737239 39275.873737302296 42207.728818344935 36676.150684011656 1.246226306870184 1.0143012161476221 1.3618058802732504 0.9831211659479292 1.1986702207153404 1.3585617247774777 1.070382391151153 1.0708832035206994 1.1508222109236963 1.0 15.162554609526508 -8.469925573993553 0.7980531570065831 1.0082496146210274 1.177509144177806 0.15071097900417008 0.12403415183312491 1.3077089333127292 1.8774408453203135 0.11681066845947939 0.043492726498062864 3.3890222958803964e-09 8.469925573993553 0.1692595295567787 S(ph)GLCSPSYVAVTPFSLR ddPTM_PC-9_AZD4547_30min_R2 2 SGLCSPSYVAVTPFSLR 17 0 H0YBT0;A0A087WUS5;P01106;P01106-2;H0YBG3;A0A0B4J1R1 H0YBT0 MYC Myc proto-oncogene protein 1 S(0.998)GLCS(0.002)PSYVAVTPFSLR;S(0.997)GLCS(0.002)PSYVAVTPFSLR 193.31 5.1326e-12 39106000.0 51659.0 44667.0 60776.0 101884.0 74464.0 58188.0 47869.0 46349.0 40800.0 61442.0 True False 68085.48742604913 59104.73423920774 59970.07052966707 78396.21789210856 64125.95894220176 54549.4951614677 52129.24826545937 39186.82704406398 42956.604705149155 59290.934281489266 1.1483288001974619 0.9968595529057187 1.011454301680482 1.3222294241462813 1.0815474527312685 0.920030959581255 0.8792111120727307 0.6609244316849664 0.7245054446470458 1.0 15.855523909835128 -7.019464103574 2.0050850893637615 0.7811213321407664 1.1126731570663506 0.578793946857706 0.11931455037559295 0.23391341075106162 1.8829376466837375 0.05482985449882466 0.04194665642901232 9.561717237215593e-08 7.019464103574 0.3315518249255842 S(ph)GLCSPSYVAVTPFSLR ddPTM_PC-9_Lapatinib_30min_R1 1 SGLCSPSYVAVTPFSLR 17 0 H0YBT0;A0A087WUS5;P01106;P01106-2;H0YBG3;A0A0B4J1R1 H0YBT0 MYC Myc proto-oncogene protein 1 S(0.67)GLCS(0.109)PS(0.221)YVAVTPFSLR 153.22 2.7049e-05 8839500.0 19908.0 17894.0 19677.0 21216.0 26762.0 26440.0 23229.0 23872.0 33780.0 29313.0 True False 19624.10826931993 17852.567542404086 18059.23301541653 22776.295414501263 25187.911776116383 25309.22283465035 24431.683959630074 24981.18026902057 29975.340680830253 34379.71299288269 0.5708048893073228 0.519276223920192 0.5252874862322197 0.6624923081590712 0.7326388030444233 0.7361673682351532 0.7106424641964851 0.7266256200042214 0.8718903699700974 1.0 15.06926988057621 -5.847093445223411 0.1088033125540343 1.2395308881167546 4.412776637467344e-09 0.8946581337834628 0.04632451632646526 10.339341541831391 0.27992573853858016 0.8884941786173264 2.4138582748210426 1.422022783848476e-06 5.847093445223411 -1.239530883703978 S(ph)GLFPR ddPTM_PC-9_AZD4547_30min_R2 1 SGLFPR 6 0 A0A1B0GV05;Q684P5-3;Q684P5-2;Q684P5 A0A1B0GV05 RAP1GAP2 Rap1 GTPase-activating protein 2 1 S(1)GLFPR 96.492 0.034658 4367100.0 9280.5 6770.4 10837.0 17388.0 14375.0 12229.0 7758.3 13798.0 9863.8 12596.0 True False 12231.505953608239 8958.799397611934 10693.294299229992 13379.465241922038 12379.279380561751 11464.31869680327 8448.773670181405 11665.836146497115 10385.180330653186 12155.017873924011 1.0062927163478974 0.7370453495449909 0.8797431982531401 1.1007359578322642 1.0184501173888725 0.9431757991403297 0.6950852526762993 0.9597547504659512 0.8543944927413366 1.0 13.569264394397175 -10.154144089376143 15.020430404689439 0.9999999993291385 0.909353627308091 0.048507559368769826 0.11878931055691885 0.0 0.0 0.12005989488985488 0.0291188016489074 7.012226095518686e-11 10.154144089376143 -0.09064637202104753 S(ph)GLFPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGLFPR 6 0 A0A1B0GV05;Q684P5-3;Q684P5-2;Q684P5 A0A1B0GV05 RAP1GAP2 Rap1 GTPase-activating protein 2 1 S(1)GLFPR 93.195 0.034816 2563400.0 7257.0 9265.5 10782.0 11553.0 14390.0 12284.0 10998.0 12910.0 11773.0 8418.9 True False 8485.466767716558 10185.317606443745 11039.083770962703 10905.722865331354 11570.382799479326 11639.8054152539 9956.189821375312 12571.126179275678 11945.157852672208 9945.179926024271 0.8532240573659229 1.024146137345498 1.1099933689561448 1.0965837668550933 1.1634161358109036 1.1703966646993667 1.0011070584376487 1.2640421061040739 1.2011002255891268 1.0 13.279781756880967 -4.057807799888807 0.943322511504447 1.1404374601459624 0.056238353715455464 0.5369052147790014 0.07797907472276065 5.1208463999099045 1.3536730234657675 0.025313593574600265 7.877035255312275 8.753710912174903e-05 4.057807799888807 -1.084199106430507 S(ph)GLFPR ddPTM_PC-9_Lapatinib_30min_R1 1 SGLFPR 6 0 A0A1B0GV05;Q684P5-3;Q684P5-2;Q684P5 A0A1B0GV05 RAP1GAP2 Rap1 GTPase-activating protein 2 1 S(1)GLFPR 93.195 0.034816 3537100.0 9030.1 7651.9 8381.7 10026.0 11837.0 9729.8 10477.0 9678.0 12767.0 11405.0 True False 8901.32911808247 7634.18249568133 7692.588980297643 10763.345485755543 11140.7709324374 9313.679135271594 11019.447795645287 10127.67521127602 11329.0460175299 13376.339053792752 0.6654533114244418 0.5707228610893142 0.5750892639130938 0.8046555520513428 0.8328714521690092 0.6962801329883138 0.8238014714886291 0.7571335602774214 0.8469466848866725 1.0 13.707395700937493 -4.412218465431567 0.09293574598396395 1.1988783436309594 7.728221865036969e-16 0.7039670195861947 0.06871199553684201 44.389312136166744 0.5929449882889154 1.7344066943024086 7.4451204854207695 3.870628896654009e-05 4.412218465431567 -1.1988783436309587 S(ph)GLNGSILAER ddPTM_PC-9_AZD4547_30min_R2 1 SGLNGSILAER 11 0 Q96H22-5;Q96H22-4;Q96H22;Q96H22-3 Q96H22-5 CENPN Centromere protein N 1 S(0.929)GLNGS(0.071)ILAER 91.85799999999999 0.0079633 2226000.0 6937.7 8306.2 8370.9 11505.0 12646.0 13851.0 13846.0 11835.0 7247.7 11182.0 True False 9143.74428687548 10991.016713406041 8259.896396551101 8852.700000478084 10890.321185849309 12984.894780392686 15078.267176743842 10006.172691244627 7630.798625527195 10790.521583535903 0.8473866824776048 1.0185806708524685 0.7654770283907304 0.8204144657831431 1.0092488209713308 1.2033611795193424 1.3973622183148355 0.9273113087055931 0.7071760680382875 1.0 13.397476981891026 -6.413295836377998 4.95140192407083 1.0683425735037222 0.8685565328584495 0.1892517336561459 0.17828077801156988 0.39822861632213097 14.845156280496164 0.06142274756134948 0.0694681681084843 3.8610387795824655e-07 6.413295836377998 -0.19978604064527272 S(ph)GLNGSILAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGLNGSILAER 11 0 Q96H22-5;Q96H22-4;Q96H22;Q96H22-3 Q96H22-5 CENPN Centromere protein N 1 S(0.934)GLNGS(0.066)ILAER 96.665 0.005710600000000001 6096000.0 15573.0 23692.0 19403.0 18434.0 25088.0 14424.0 19423.0 16094.0 18633.0 9316.9 True False 18209.201319229716 26043.98518502673 19865.641106287265 17401.202743834365 20172.18649571489 13667.580047999212 17583.112829657442 15671.549553002538 18905.472374827244 11005.980217460183 1.6544824685712365 2.3663485369263024 1.8049860815460923 1.5810679648713732 1.8328387019734227 1.2418321474280496 1.5975962596919009 1.423912204397821 1.7177454439573765 1.0 13.426000020180375 -1.522878757980462 0.06754267133487254 0.3056679165922996 4.670114511237507 0.4919275950309624 0.24847065374499105 217.05136387727342 1.0900102663796785 12.772975591600929 90.72333470267947 0.029999999122706504 1.522878757980462 4.364446594645208 S(ph)GLNGSILAER ddPTM_PC-9_Lapatinib_30min_R1 1 SGLNGSILAER 11 0 Q96H22-5;Q96H22-4;Q96H22;Q96H22-3 Q96H22-5 CENPN Centromere protein N 1 S(0.83)GLNGS(0.17)ILAER 84.29700000000001 0.012085 2546300.0 6723.0 10328.0 11992.0 8908.2 11069.0 9709.1 9117.9 9387.1 11016.0 8116.8 True False 6627.128787152797 10304.086150550429 11006.064050458663 9563.338744884059 10417.943182491299 9293.864426017537 9589.980247772664 9823.258935293366 9775.262076377325 9519.778065043834 0.6961432022756175 1.0823872237512067 1.1561261171489279 1.0045758083374 1.0943472748325387 0.9762690225042282 1.0073743507725887 1.031878985851981 1.0268371814540105 1.0 13.21671222498177 -4.757596180805941 24.998402281538112 1.0440612449862163 0.6961427035459619 0.8029430341577247 0.05142315307066345 49.04272634751165 318957.2034747575 0.013284915393988147 0.09740469188789626 1.747446222275571e-05 4.757596180805941 -0.34791854144025447 S(ph)GLQLSLEQGTGENSFR ddPTM_PC-9_AZD4547_30min_R2 1 SGLQLSLEQGTGENSFR 17 0 P23497;P23497-5;P23497-2;P23497-3;P23497-4;E9PHV6;P23497-7;P23497-6;C9JBL0 P23497 SP100 Nuclear autoantigen Sp-100 1 S(1)GLQLSLEQGTGENSFR 97.77600000000001 0.0014208 2735700.0 7892.3 11504.0 9191.6 13063.0 9906.3 9456.0 8980.8 10593.0 14223.0 10722.0 True False 10401.887229962002 15222.443027018733 9069.713378315246 10051.527171338135 8530.981240184967 8864.71482516736 9780.073801885099 8956.095252923895 14974.798743170008 10346.626043522807 1.005340986154012 1.4712470483601061 0.8765865645635339 0.9714787341358095 0.8245181766790084 0.8567734822809072 0.9452428028949224 0.8656053881961442 1.44731226200492 1.0 13.336872772024412 -5.282466620895161 24.986221234936735 0.9580775227099757 1.2382940811781435 0.21910727219211423 0.1983126854103589 948.0899773635941 1126593.8071261174 0.050112451506514506 0.10447567633839079 5.218352100279394e-06 5.282466620895161 0.28021655846816784 S(ph)GLQLSLEQGTGENSFR ddPTM_PC-9_Lapatinib_30min_R1 1 SGLQLSLEQGTGENSFR 17 0 P23497;P23497-5;P23497-2;P23497-3;P23497-4;E9PHV6;P23497-7;P23497-6;C9JBL0 P23497 SP100 Nuclear autoantigen Sp-100 1 S(0.999)GLQLS(0.001)LEQGTGENSFR 82.367 0.0045003 2026200.0 4226.2 4305.2 6073.9 5204.7 6132.4 6591.4 5018.8 7077.3 6436.8 3526.8 True False 4165.933613009837 4295.231573910701 5574.527387932025 5587.471000370223 5771.70428876228 6309.501187303867 5278.648906822999 7406.137194953896 5711.81980149107 4136.402680834395 1.0071392788502607 1.038397831481017 1.3476752187984586 1.3508044142460323 1.395343909698369 1.5253595150535764 1.2761448326298324 1.7904778055747537 1.380866478004236 1.0 12.01416092422312 -5.291126234865046 1.738825058008972 1.4275657369471724 0.9703430610100728 0.35688768465121645 0.1889851633806173 0.4190687828833569 2.207798891858763 0.05242663996881172 0.22462271960947033 5.115331283757504e-06 5.291126234865046 -0.45722267593709953 S(ph)GLSDIILGK ddPTM_PC-9_AZD4547_30min_R2 1 SGLSDIILGK 10 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;K7EJR2;M0R330;M0QX30;M0R1V5 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 S(0.892)GLS(0.108)DIILGK 89.171 0.0095196 4645000.0 19723.0 23970.0 28157.0 32928.0 25758.0 24908.0 29933.0 29471.0 18859.0 25849.0 True False 25994.503736114995 31717.83374110214 27783.61978254302 25336.958332528695 22181.94631544415 23350.4988224692 32596.979012095406 24916.934126207892 19855.848238588416 24944.03437782327 1.0421130496526918 1.2715598952710383 1.1138382573447827 1.0157522215033008 0.8892685914178029 0.9361155644986274 1.3068046057968898 0.998913557798835 0.7960159105714449 1.0 14.606407201018863 -5.693838638448751 3.776245557308859 0.9975237930057734 1.1634622281983558 0.2131008158638772 0.13367749406673868 0.3615363065907747 10.195323956514441 0.03921886074774493 0.06978249007108109 2.0237709684838326e-06 5.693838638448751 0.16593843519258233 S(ph)GLSDIILGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGLSDIILGK 10 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;K7EJR2;M0R330;M0QX30;M0R1V5 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 S(0.959)GLS(0.041)DIILGK 76.143 0.023541 6150500.0 27311.0 24678.0 24596.0 29557.0 30372.0 25306.0 28407.0 23128.0 24940.0 19866.0 True False 31934.212883162065 27127.868748779758 25182.461920849433 27901.017115086917 24420.824627226284 23978.908811333047 25716.08331113005 22520.914506141602 25304.700318155516 23467.548540830536 1.3607817973658654 1.155973692845707 1.0730759489869668 1.1889191180980285 1.0406210339668487 1.0217901017489242 1.0958146423512174 0.9596619973730144 1.0782847758524317 1.0 14.518379522956954 -1.5228787452803547 0.5464952498893006 1.0330685775495578 14.472452302297764 0.7535059897870111 0.05428142951840843 65.0227017114806 0.6021780217253644 0.026736850007119832 1024.3358106394267 0.029999999999998816 1.5228787452803547 13.439383724748206 S(ph)GLSEPR ddPTM_PC-9_Lapatinib_30min_R1 1 SGLSEPR 7 0 C9J8G2 C9J8G2 CABP1 1 S(0.905)GLS(0.095)EPR 124.08 0.0046531 2240900.0 8285.2 11663.0 6942.3 11939.0 13245.0 6658.4 17922.0 17366.0 11120.0 10774.0 True False 8167.051528680404 11635.995040072585 6371.530892052964 12817.033887336478 12465.955140671911 6373.635753488494 18849.913466980524 18172.88775769988 9867.548501208783 12636.271544547402 0.6463181405914402 0.9208408508040934 0.504225543871151 1.0143050378548628 0.9865216252060535 0.5043921168533879 1.4917306422648327 1.4381526776813804 0.7808908241977964 1.0 13.625283224577089 -7.261270467889711 24.99999999480857 1.2142062532217388 0.7798046849500375 0.38525145098991764 0.25456759799612244 15.793789699908713 2337830.5716046654 0.10057363314307269 0.0728751368821648 5.479356178548543e-08 7.261270467889711 -0.4344015682717013 S(ph)GMSPEQSR ddPTM_PC-9_AZD4547_30min_R2 1 SGMSPEQSR 9 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.881)GMS(0.119)PEQSR 69.346 0.040614 396000000.0 22945.0 21538.0 32722.0 48537.0 31526.0 29964.0 25044.0 33363.0 20449.0 28028.0 True False 30241.032714351713 28499.73730145426 32288.08489982503 37347.544539174705 27149.159078371453 28090.34634320166 27272.86748334341 28207.514955470564 21529.89239253908 27046.748251059256 1.118102347596161 1.0537213951528572 1.1937880517137769 1.3808515608789322 1.0037864377026613 1.0385849745209772 1.0083603111984192 1.0429170521216298 0.7960251706670833 1.0 14.723167533155364 -6.482712210845435 24.875006379760077 0.9861839077285796 1.1794711593123925 0.49435756924900887 0.10156068029126092 466.2813842650357 288766.68383942725 0.03278626289883221 0.03717073683160398 3.2906961959263043e-07 6.482712210845435 0.193287251583813 S(ph)GMSPEQSR ddPTM_PC-9_Lapatinib_30min_R1 3 SGMSPEQSR 9 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.56)GMS(0.44)PEQSR;S(0.692)GMS(0.308)PEQS(0.001)R;S(0.996)GMS(0.004)PEQSR 82.75 0.01349 66923000.0 505075.0 457365.0 475602.0 466808.0 470122.0 472505.0 425292.0 418571.0 480025.0 403126.0 True False 497872.5378805883 456305.9994429215 436499.83943681134 501138.6175458384 442470.34825541393 452297.0626129523 447311.53879026225 438019.3367285606 425959.5296126566 472805.7919683689 1.0530170026214407 0.9651023891717653 0.9232117009810521 1.059924869912264 0.9358395260204755 0.9566233542316913 0.9460788052701937 0.9264254883702111 0.9009185945868312 1.0 18.850888183372014 S(ph)GNSDSIER ddPTM_PC-9_AZD4547_30min_R2 1 SGNSDSIER 9 0 A0A5F9ZI51;A0A5F9ZGW5;C9J8U3;A0A0A0MRW7;Q7Z2E3-13;Q7Z2E3-4;Q7Z2E3-5;Q7Z2E3-9;Q7Z2E3-10;Q7Z2E3-11;Q7Z2E3-8;Q7Z2E3-7;Q7Z2E3 A0A5F9ZI51 APTX Aprataxin 1 S(0.97)GNS(0.028)DS(0.002)IER 105.25 0.0026486 47533000.0 15219.0 12413.0 17689.0 23126.0 21804.0 18294.0 14190.0 23559.0 17787.0 20205.0 True False 20058.325425134833 16425.259500554897 17454.43230221273 17794.657993138324 18776.89096443606 17150.073288030006 15452.882510327536 19918.497881962998 18727.184507119793 19497.629099923364 1.0287571541307898 0.8424234257599791 0.8952079359372639 0.9126575288688955 0.9630345755479502 0.8795978834214984 0.7925518754681959 1.0215856389452647 0.9604852164919581 1.0 14.251011083332587 -7.808602121877099 24.999958376840407 0.9932767073899952 0.9013691800230206 0.31911028146014886 0.06156904152168339 150.9724672450082 80025.25332787797 0.03314521591207961 0.015922506303805824 1.553809878256321e-08 7.808602121877099 -0.0919075273669746 S(ph)GNSDSIER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGNSDSIER 9 0 A0A5F9ZI51;A0A5F9ZGW5;C9J8U3;A0A0A0MRW7;Q7Z2E3-13;Q7Z2E3-4;Q7Z2E3-5;Q7Z2E3-9;Q7Z2E3-10;Q7Z2E3-11;Q7Z2E3-8;Q7Z2E3-7;Q7Z2E3 A0A5F9ZI51 APTX Aprataxin 1 S(0.963)GNS(0.024)DS(0.013)IER;S(0.913)GNS(0.073)DS(0.013)IER 89.301 0.009451799999999998 75326000.0 26337.0 31698.0 36001.0 30860.0 45261.0 33045.0 37367.0 31377.0 26847.5 26641.0 True False 30795.333920538953 34844.767955216 36859.4003745528 29131.014249469914 36392.43195880707 31312.06202760219 33827.32724634763 30553.38699667955 27240.093897020044 31470.80240996002 0.9785366613592512 1.1072093905107476 1.1712253120971385 0.9256520971403768 1.1563871643542663 0.9949559474115096 1.074879718848281 0.9708486805855919 0.8655671864406921 1.0 14.941726343000273 -7.891509609326293 4.1811166597212095 0.9282904673589735 1.0607397908831122 0.30572297412183747 0.07895787650949003 0.24238688963489977 7.519562700927022 0.044786762543117795 0.020116932495710532 1.2837793648818043e-08 7.891509609326293 0.13244932352413874 S(ph)GNSDSIER ddPTM_PC-9_Lapatinib_30min_R1 2 SGNSDSIER 9 0 A0A5F9ZI51;A0A5F9ZGW5;C9J8U3;A0A0A0MRW7;Q7Z2E3-13;Q7Z2E3-4;Q7Z2E3-5;Q7Z2E3-9;Q7Z2E3-10;Q7Z2E3-11;Q7Z2E3-8;Q7Z2E3-7;Q7Z2E3 A0A5F9ZI51 APTX Aprataxin 1 S(0.999)GNS(0.001)DSIER;S(0.997)GNS(0.003)DSIER 94.538 0.0057152 85182000.0 36856.0 38610.6 44156.0 39506.4 44511.0 45152.0 35431.1 44338.0 49314.0 30147.0 True False 36330.42668143739 38521.19952792818 40525.66412708912 42411.832445487 41892.950491993004 43220.954214452824 37265.54899229623 46398.10534382684 43759.73802055845 35357.868781647514 1.0275061233411977 1.0894661034525528 1.1461568675803206 1.199501947003685 1.1848267991123245 1.2223857292237772 1.0539534840866567 1.3122427041731022 1.2376237462386852 1.0 15.109743697525088 -5.097324148951739 1.6230775845605114 1.183646620494528 1.0152662098445004 0.22671400962187016 0.08491382984171367 0.7819974722911125 3.028661155704696 0.02366513047209739 0.17189390461742873 7.992374970125007e-06 5.097324148951739 -0.1683804106500275 S(ph)GPFVDQLK ddPTM_PC-9_Lapatinib_30min_R1 1 SGPFVDQLK 9 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 S(1)GPFVDQLK 73.499 0.029427 2072000.0 14445.0 16053.0 16078.0 15683.0 16806.0 14663.0 12496.0 11631.0 15885.0 10422.0 True False 14239.011651111434 16015.830264793387 14756.128902874781 16836.380136954347 15817.504121867283 14035.897671122473 13142.981736602418 12171.418721053054 14095.8640235343 12223.428813557925 1.1648950444508561 1.3102567625729553 1.2072004613392642 1.3773860341281532 1.2940316799098874 1.1482782683328758 1.07522872158625 0.9957450488485537 1.1531841219461691 1.0 13.577361414169543 -6.986616544983117 2.8075279763737893 1.0564703611415944 1.2751129935000405 0.6902809059614585 0.06779711785940151 0.15283498731305883 2.4465400620370428 0.02675825975703452 0.02173205781204029 1.0312962890538409e-07 6.986616544983117 0.21864263235844605 S(ph)GPGPPELDSEQPSR ddPTM_PC-9_Lapatinib_30min_R1 1 SGPGPPELDSEQPSR 15 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 S(1)GPGPPELDSEQPSR 132.81 5.6387e-06 3023300.0 2798.7 5301.2 5106.5 2074.9 5286.0 4435.9 4602.8 2639.2 4701.0 2401.9 True False 2758.7900247812768 5288.925397104757 4686.663281660037 2227.495067663492 4975.0878726758565 4246.186897587953 4841.110462326636 2761.8268668732862 4171.523876275402 2817.0652146694265 0.9793135105340512 1.877459339444293 1.663668720644084 0.7907147680018766 1.7660534966563304 1.5073086968227072 1.7184942816081468 0.9803915267887675 1.4808048654865509 1.0 11.459977246951835 -8.66653532625699 0.8758877862565063 1.0137835505463408 1.4631274919217716 0.10568014195761333 0.3575744542894146 1.7184317891356353 2.783816619904543 0.3376710028703189 0.11673677250265084 2.1550863380225934e-09 8.66653532625699 0.44934394137543077 S(ph)GPIFR ddPTM_PC-9_Lapatinib_30min_R1 1 SGPIFR 6 0 A0A087WYN8 A0A087WYN8 1 S(1)GPIFR 108.09 0.031224000000000002 1720000.0 8255.2 7022.2 5962.7 5430.7 6157.7 5511.3 4732.1 3772.5 5916.8 3690.5 True False 8137.479334181727 7005.9405273426855 5472.469822687615 5830.091794284123 5795.516192503991 5275.594546467794 4977.104983656874 3947.7841221883455 5250.387677333824 4328.398007717858 1.880021042351464 1.6185989631384565 1.2643176096398234 1.3469398571685491 1.3389517743447235 1.2188330502557791 1.149872302589162 0.9120658763702301 1.2130094478308118 1.0 12.079617449575474 -1.5228787452994639 0.3360100892277561 1.0407245047411133 10.007138649771356 0.8596571271653948 0.10050676925292279 21.247181490318454 0.3016995775523215 0.09290778743437661 119.03741426197782 0.029999999998678802 1.5228787452994639 8.966414145030242 S(ph)GPLEESER ddPTM_PC-9_AZD4547_30min_R2 1 SGPLEESER 9 0 A0A2R8Y4Z8;Q9Y3X0 A0A2R8Y4Z8;Q9Y3X0 CCDC9 Coiled-coil domain-containing protein 9 1 S(1)GPLEESER 82.417 0.015806 13896000.0 11152.0 4567.2 17717.0 25576.0 19068.0 12456.0 11163.0 22374.0 12629.0 18825.0 True False 14698.104023989985 6043.458083536162 17482.061003917846 19679.848345260987 16420.737337638362 11677.124350918437 12156.485374403548 18916.61240337195 13296.5431573855 18165.94247988406 0.8091021999142537 0.3326806792561601 0.9623536473968524 1.0833375899463153 0.9039298322023072 0.6428031115836146 0.6691910088268173 1.041322927468208 0.7319489848715167 1.0 14.148948596708419 -5.280197311210124 24.993268500429902 0.8730444983360285 0.5708913933357013 0.3181841739236523 0.18043076791892024 858.6352236421251 1144053.7673852055 0.04802730602816116 0.10023936317890313 5.245690808087965e-06 5.280197311210124 -0.3021531050003272 S(ph)GPLEESER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGPLEESER 9 0 A0A2R8Y4Z8;Q9Y3X0 A0A2R8Y4Z8;Q9Y3X0 CCDC9 Coiled-coil domain-containing protein 9 1 S(1)GPLEESER;S(1)GPLEESER 102.52 0.0031496 18275300.0 10407.400000000001 6220.3 10583.6 14196.6 11176.4 7692.9 10967.099999999999 11044.400000000001 7347.7 8729.1 True False 12169.16726448028 6837.810275469437 10835.953162526515 13401.210527998204 8986.464650458704 7289.470781423533 9928.216893071933 10754.496202509094 7455.146212017294 10311.616730482423 1.1801415415787038 0.6631171865858841 1.050849100170111 1.299622637096524 0.871489397379714 0.7069183205650913 0.9628186493513561 1.0429495668431377 0.722985192998781 1.0 13.33198292624099 S(ph)GPLEESER ddPTM_PC-9_Lapatinib_30min_R1 1 SGPLEESER 9 0 A0A2R8Y4Z8;Q9Y3X0 A0A2R8Y4Z8;Q9Y3X0 CCDC9 Coiled-coil domain-containing protein 9 1 S(1)GPLEESER 130.98 0.0012483 8127900.0 5874.9 4067.9 9824.8 6700.7 5697.6 2935.9 4443.2 4109.4 4027.5 6397.4 True False 5791.122848675288 4058.4810274810325 9017.042868824736 7193.4918308799315 5362.478369912588 2810.33840091717 4673.247155255428 4300.337726102262 3573.880538544814 7503.182066000324 0.7718222479122551 0.5409013125073296 1.2017625041626367 0.9587254804166737 0.7146938889050752 0.37455287319387415 0.6228353669347341 0.5731351962774132 0.4763153162362114 1.0 12.873286850569585 -6.521093001163119 24.811215613818064 0.5792074026379355 0.8647323853935216 0.23612564367321598 0.216194310540929 84.74024872112723 1177411.0768531912 0.07082245027419234 0.07186936028659599 3.012360878839578e-07 6.521093001163119 0.28552498275558613 S(ph)GPPSPPSTATSFGGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGPPSPPSTATSFGGPR 17 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2;A0A087X0E3 A0A0A0MS59 SRCAP Helicase SRCAP 1 S(0.982)GPPS(0.012)PPS(0.005)T(0.001)ATSFGGPR;S(0.674)GPPS(0.304)PPS(0.014)T(0.004)AT(0.003)S(0.001)FGGPR 117.86 0.00012043 16362400.0 30882.0 56119.0 34781.0 42845.0 39619.0 31568.0 40801.0 21594.7 26853.0 30526.0 True False 36109.71265269712 61690.12344244963 35610.31094767704 40444.53355536416 31855.94135737121 29912.51850771207 36936.033906340585 21027.86200647595 27245.674324115094 36060.122156316975 1.001375217093419 1.7107574726183454 0.9875260764040108 1.1215861493768993 0.8834119091244044 0.8295179472228168 1.0242903156630092 0.5831334102342277 0.7555624522293035 1.0 15.138116663563581 -5.910747494499261 1.1808825677903647 0.817159935192655 1.3412385502194717 0.4186677418467174 0.2150915597287001 0.4348675685407822 1.222475930486847 0.0773098782474702 0.1688854591684367 1.2281530907366673e-06 5.910747494499261 0.5240786150268167 S(ph)GRESVSTASDQPSHSLER ddPTM_PC-9_AZD4547_30min_R2 1 SGRESVSTASDQPSHSLER 19 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.511)GRES(0.387)VS(0.069)T(0.023)AS(0.01)DQPSHSLER 48.255 0.034786000000000004 5182700.0 1556.0 1998.3 7234.3 6484.7 7969.3 6260.7 5190.4 6508.1 4903.7 4200.7 True False 2050.7756331894216 2644.2113961136592 7138.368455192353 4989.752602616275 6862.900255131178 5869.217439289906 5652.335544862866 5502.422686260168 5162.899570898036 4053.6347715935703 0.5059103122857854 0.6523062745177123 1.7609796780942129 1.2309329487655585 1.6930238272140203 1.4478900468338423 1.3943869794270618 1.357404649481297 1.2736469518856997 1.0 11.985000393953527 -5.1676253730019654 6.1750266964082785 1.413121832263275 0.5520351249895562 0.710600404570088 0.20834192620921632 0.10968768663408128 5.920152876460455 0.04975340414747844 0.13588842356115682 6.797897735995882e-06 5.1676253730019654 -0.8610867072737188 S(ph)GRESVSTASDQPSHSLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGRESVSTASDQPSHSLER 19 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.829)GRES(0.165)VS(0.005)T(0.001)ASDQPSHSLER 108.34 8.7464e-05 2816800.0 7069.5 7359.1 5587.3 6741.5 8350.7 8511.3 8976.5 9024.8 8641.3 5195.3 True False 8266.226721010373 8089.6628134024295 5720.522421953247 6363.795611237894 6714.440281001534 8064.9524447126805 8126.180935767907 8787.90856256601 8767.662664766529 6137.16676402783 1.3469125149835814 1.318142902816148 0.9321112887926255 1.0369272753900738 1.0940618919396674 1.3141165548872331 1.324093225460063 1.4319162083186565 1.4286173085856153 1.0 12.583357070739298 -6.792358718225439 9.185555146324837 1.3286149625759218 1.137338630324115 0.17452016819193716 0.16111124220420817 0.456460521360637 126.25482430641524 0.05865287343957668 0.052224951654116274 1.613025680714859e-07 6.792358718225439 -0.19127633225180674 S(ph)GRSPTGNTPPVIDSVSEK ddPTM_PC-9_AZD4547_30min_R2 1 SGRSPTGNTPPVIDSVSEK 19 1 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 S(0.536)GRS(0.354)PT(0.098)GNT(0.013)PPVIDSVSEK 92.56299999999999 0.00041083 8545400.0 32238.0 30092.0 30760.0 61719.0 49993.0 32872.0 28972.0 41439.0 34254.0 46726.0 True False 42489.01340794381 39818.65051886715 30352.102301773033 47490.638099044496 43052.33489199467 30816.508643496352 31550.4518737991 35035.55472348844 36064.59650907301 45090.13696228751 0.9423128043164022 0.8830900325756533 0.673142827824163 1.0532378320066917 0.9548060350316253 0.683442338382575 0.6997195839122703 0.7770114948373628 0.7998333768477287 1.0 15.460524271749609 -6.752812145497999 24.999568148768027 0.772296961255156 0.8960688470964251 0.15998421222443493 0.12080849532132439 321.8616995067275 932673.5359340534 0.0405214919060311 0.039908656101031635 1.766801887306051e-07 6.752812145497999 0.12377188584126908 S(ph)GRSPTGNTPPVIDSVSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGRSPTGNTPPVIDSVSEK 19 1 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 S(0.977)GRS(0.017)PT(0.005)GNTPPVIDSVSEK 104.3 0.000797 0.0 9405.9 8087.0 4747.8 13888.0 10470.0 11019.0 13881.0 14181.0 9944.0 7784.8 True False 10998.13309500692 8889.823914878916 4861.005558131768 13109.900385503495 8418.478659523875 10441.144242159127 12566.091190262838 13808.7637760115 10089.412187800253 9196.122615557106 1.1959532897485892 0.9666926254158439 0.5285929474133362 1.4255899941270294 0.9154378439106837 1.1353854965456653 1.3664553764218788 1.5015854347843487 1.0971376317592771 1.0 13.166809986872687 -7.009461507995805 4.910529859273297 1.281001567482861 1.0017246724726314 0.15821452144849013 0.24879363117524375 0.3003944712052047 20.428330343310886 0.09312892716427817 0.07639303502914115 9.784496720270757e-08 7.009461507995805 -0.27927689501022956 S(ph)GS(ph)LQIKNRNHMK ddPTM_PC-9_AZD4547_30min_R2 3 SGSLQIKNRNHMK 13 2 A6NHS7 A6NHS7 MANSC4 MANSC domain-containing protein 4 2 S(1)GS(1)LQIKNRNHMK;S(1)GS(1)LQIKNRNHMK;S(1)GS(1)LQIKNRNHMK 78.705 0.017937 25056400.0 3133.6 5414.3 50708.0 64982.0 46082.5 41141.1 22884.9 68004.0 33563.8 37558.3 True False 4130.019617070929 7164.366592592797 50035.57878798137 50001.403861891966 39684.74031685123 38568.54051329242 24921.611766074322 57495.544376459555 35337.91394614426 36243.39534885679 0.11395233744846148 0.19767371471775697 1.3805433598692793 1.379600431488523 1.0949509540943985 1.0641536241860123 0.6876180205026076 1.5863730156361608 0.9750166507856971 1.0 15.145430495626272 -5.251446792391077 23.93879475052748 1.1541951480111747 0.15581265770414382 0.730866709815333 0.24031564790881305 189.65879097315394 454352.4436991389 0.06154128077997808 0.15834404651904305 5.604710792987397e-06 5.251446792391077 -0.9983824903070309 S(ph)GS(ph)LQIKNRNHMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGSLQIKNRNHMK 13 2 A6NHS7 A6NHS7 MANSC4 MANSC domain-containing protein 4 2 S(1)GS(1)LQIKNRNHMK;S(1)GS(1)LQIKNRNHMK 86.911 0.0089821 9683600.0 2406.1 3388.0 38047.0 12977.5 32086.0 25746.0 14788.400000000001 11489.400000000001 26031.0 13000.400000000001 True False 2813.4052073588005 3724.3382494880375 38954.184774051 12250.412748622673 25798.978631278234 24395.834436757308 13387.53569325574 11187.815424025564 26411.65412918631 15357.269608890221 0.1831969665838346 0.2425130471976635 2.5365306311677096 0.7976947114043625 1.6799196268810295 1.5885528520404903 0.8717393152690232 0.7285028985588046 1.719814446306053 1.0 13.9066341195757 -5.055694865962431 24.996935568141524 1.340457716185013 0.1980214910903142 0.43496851553977267 0.5249948640288489 225.60288020512112 101254.72263023238 0.12935910322087124 0.34225546208114904 8.796403325023079e-06 5.055694865962431 -1.1424362250946989 S(ph)GS(ph)LQIKNRNHMK ddPTM_PC-9_Lapatinib_30min_R1 2 SGSLQIKNRNHMK 13 2 A6NHS7 A6NHS7 MANSC4 MANSC domain-containing protein 4 2 S(1)GS(1)LQIKNRNHMK;S(1)GS(1)LQIKNRNHMK 86.67 0.0091277 8637600.0 16868.6 3714.41 86092.0 20121.7 46280.0 58931.0 26883.0 31257.0 86543.0 27254.0 True False 16628.050670677625 3705.809511857669 79013.8480847303 21601.51694202347 43557.90138998083 56410.658504870626 28274.87020047078 32709.314329288565 76795.61600180858 31964.81758632773 0.5201985159392845 0.11593401094341768 2.4719004846918566 0.6757904024849828 1.3626826204261462 1.764773359100885 0.8845622260821147 1.0232911306610828 2.4025044345836113 1.0 14.964197240384769 -5.224386853269025 24.998337072603178 1.4095579121803075 0.3180657223985604 0.37023800095692727 0.5878418871642479 597.9802005267426 403439.3208221831 0.14224142034519494 0.37631470445890597 5.9650370668820595e-06 5.224386853269025 -1.0914921897817471 S(ph)GSDAGEARPPTPASPR ddPTM_PC-9_AZD4547_30min_R2 1 SGSDAGEARPPTPASPR 17 1 Q96FS4;F6RY50;E9PIB3 Q96FS4 SIPA1 Signal-induced proliferation-associated protein 1 1 S(0.5)GS(0.5)DAGEARPPTPASPR 84.94 0.037607 0.0 5661.4 4535.0 6252.1 8003.3 7343.1 6002.8 4596.6 5643.6 5292.5 6096.7 True False 7461.607435564641 6000.850063241478 6169.193068950431 6158.262834752391 6323.637316132378 5627.443967059501 5005.688495205888 4771.511297026462 5572.2507451471065 5883.256388691052 1.2682784741299964 1.0199878548173538 1.0486017710887143 1.0467439166156287 1.074853261246244 0.9565185664654561 0.8508363675647304 0.8110323572160453 0.9471371595938316 1.0 12.522399194044905 -6.876359074879096 2.8402954867093224 0.8870172372057483 1.085034416555475 0.5563480052236799 0.08023586971849742 0.1968904971875826 3.206434519213003 0.03048054075951081 0.02650142752319623 1.3293548522714997e-07 6.876359074879096 0.19801717934972674 S(ph)GSDAGEARPPTPASPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSDAGEARPPTPASPR 17 1 Q96FS4;F6RY50;E9PIB3 Q96FS4 SIPA1 Signal-induced proliferation-associated protein 1 1 S(0.5)GS(0.5)DAGEARPPTPASPR 87.419 0.029561 0.0 4287.3 5541.6 4266.8 4307.6 7054.7 4941.9 4705.5 6480.4 5237.3 3865.9 True False 5013.055211965169 6091.73342484147 4368.5366939291125 4066.259137427626 5672.382177587687 4682.738064282255 4259.760975130159 6310.2963665513635 5313.885604501839 4566.757067552438 1.097727586077165 1.3339298181907335 0.9565949380071663 0.8904040826517942 1.242102895704897 1.0253967958037187 0.9327759090573184 1.3817893689565972 1.1636015504870783 1.0 12.15695433105469 -7.751281259872297 24.99985308148556 1.2045216351951615 1.0725086684521277 0.0950981644526957 0.15524482639287296 426.09400208809905 1048654.3812215975 0.07484185012169729 0.04257279589206946 1.773040843784668e-08 7.751281259872297 -0.13201296674303387 S(ph)GSDAGEARPPTPASPR ddPTM_PC-9_Lapatinib_30min_R1 3 SGSDAGEARPPTPASPR 17 1 Q96FS4;F6RY50;E9PIB3 Q96FS4 SIPA1 Signal-induced proliferation-associated protein 1 1 S(0.663)GS(0.337)DAGEARPPTPASPR;S(0.5)GS(0.5)DAGEARPPTPASPR;S(0.5)GS(0.5)DAGEARPPTPASPR 117.48 0.00060585 9928100.0 48493.2 38750.1 40921.3 34221.9 42613.5 39552.4 39612.9 42387.8 42264.4 38741.9 True False 47801.67807543624 38660.37652424903 37556.90867478602 36738.69268691179 40107.05771136444 37860.83605314767 41663.8621345917 44357.29193227176 37504.138208137425 45438.38579466318 1.0520109207103618 0.8508307645204632 0.8265458382369988 0.8085386847352929 0.8826690695529743 0.8332346185060671 0.9169309473904153 0.9762074764874591 0.8253844750915943 1.0 15.471623963348922 -7.439502173394189 7.387828592357446 0.9296752726498317 0.8697575929579462 0.10585782594796711 0.07660387945418917 0.6212800345139498 48.32058868002058 0.03212349865375342 0.02150086515515026 3.634944854606173e-08 7.439502173394189 -0.05991767969188555 S(ph)GSGGGSAKEPQEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSGGGSAKEPQEER 15 1 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;F6UYG0 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 S(0.57)GS(0.43)GGGS(0.001)AKEPQEER 91.932 0.0181 3866100.0 5170.0 4382.8 3286.8 6968.8 6445.3 6573.9 4362.9 6881.9 5624.8 4004.4 True False 6045.178887845479 4817.895419083875 3365.1697772584143 6578.360729154439 5182.389732973182 6229.153111310449 3949.6145273393645 6701.257416975776 5707.052058923866 4730.366021187042 1.2779516132090973 1.018503726245452 0.7113973341990892 1.3906663246967217 1.0955578722157124 1.3168437882841253 0.8349490313538666 1.416646700691072 1.2064715570343398 1.0 12.207736103854911 -5.779738547624288 24.999995614609684 1.18530839227385 1.0042059022045595 0.13057880001561195 0.20963373836931795 470.10123205206344 642242.3813362404 0.05778831997777679 0.08589559591753872 1.6605863066753577e-06 5.779738547624288 -0.18110249006929058 S(ph)GSGNFGGGR ddPTM_PC-9_AZD4547_30min_R2 1 SGSGNFGGGR 10 0 F8VZ49;F8W6I7;P09651-2;P09651;A0A2R8Y4L2;H0YH80 F8VZ49;F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 S(0.904)GS(0.096)GNFGGGR 85.973 0.011563 43710000.0 14259.0 11544.0 21239.0 28581.0 18153.0 19412.0 20398.0 23258.0 20812.0 20827.0 True False 18793.06539437529 15275.372244776105 20957.356982683927 21992.092022048186 15632.769293588695 18198.164571293237 22213.38248383798 19664.010515671092 21912.07983145991 20097.853069245426 0.9350782558527719 0.7600499512135014 1.042765956665976 1.094250811082971 0.7778327983455413 0.9054780383055356 1.1052614628688786 0.978413487645692 1.0902696798490725 1.0 14.294753774894787 -7.245834627736983 24.061786470640108 1.0416872821852914 0.9191484879076577 0.2629486387286729 0.10188647857995456 743.1429078407629 1145892.2460981316 0.04062935214323406 0.031345332745864554 5.67760758298771e-08 7.245834627736983 -0.1225387942776337 S(ph)GSGNFGGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGSGNFGGGR 10 0 F8VZ49;F8W6I7;P09651-2;P09651;A0A2R8Y4L2;H0YH80 F8VZ49;F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 S(0.999)GS(0.001)GNFGGGR;S(0.6)GS(0.4)GNFGGGR 129.74 0.00023622 74252000.0 68282.0 56446.0 79402.0 97665.0 117907.0 106565.0 107254.0 161646.0 99527.0 81100.0 True False 79840.79396902614 62049.5858413819 81295.24481376196 92193.14668420231 94803.9697524815 100976.54380303893 97094.12466828396 157402.96377809436 100982.39408841486 95802.78801275305 0.8333869569474107 0.6476803768291378 0.8485686742534061 0.9623221682434728 0.9895742255419686 1.0540042299144485 1.0134791135239092 1.642989385206005 1.0540652958343166 1.0 16.547780020830793 -6.412659910866407 0.8085524746780858 1.2306866821773614 0.7375581311499408 0.44806504373259437 0.1813087542641901 0.5458705727629082 0.7856590912048921 0.10414085915206263 0.14747808239886848 3.8666965341240586e-07 6.412659910866407 -0.4931285510274206 S(ph)GSGSESEPSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGSGSESEPSSR 12 0 O14641;I3L2N2;I3L0Z8 O14641 DVL2 Segment polarity protein dishevelled homolog DVL-2 1 S(0.593)GS(0.405)GS(0.002)ESEPSSR;S(0.968)GS(0.032)GSESEPSSR 158.34 0.00034189 10318800.0 18754.6 23339.4 25321.1 25991.8 32207.9 30859.1 25642.2 23643.8 26334.7 24937.9 True False 21929.38335976532 25656.38138727895 25924.851054806517 24535.56371255255 25896.993201344692 29240.794471659206 23213.185182548634 23023.175302676864 26719.79516714233 29458.943861692216 0.74440494074473 0.870919932083579 0.8800332821340089 0.8328731616362552 0.8790876320254166 0.992594799356786 0.7879842974525154 0.7815343079089713 0.9070180958485814 1.0 14.846418088510728 S(ph)GSGSESTGAEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSGSESTGAEER 13 0 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 S(0.868)GS(0.118)GS(0.008)ES(0.005)TGAEER 108.32 0.00090997 2038100.0 2644.1 1282.2 2775.8 2626.2 3504.7 3722.7 2288.8 2434.2 3626.8 710.19 True False 3091.693906644532 1409.4883422354085 2841.985599280123 2479.0625282552787 2817.979193699457 3527.4750585611946 2071.9882945229865 2370.3048292480908 3679.8350887685033 838.9418251390538 3.685230386662492 1.68007876112481 3.387583637052625 2.9549874067184296 3.358968535431381 4.204671829273167 2.469763972227224 2.8253506479489388 4.3862815972473115 1.0 9.71242696290316 -4.484400156773764 23.275140226872566 3.0108733092594693 8.987872311787614 0.04444503692698165 0.9861516427283294 1185.6182692344591 789086.2273550491 0.22454460667230036 33789.52826407362 3.2779312697182735e-05 4.484400156773764 5.976999002528144 S(ph)GSGSESTGAEER ddPTM_PC-9_Lapatinib_30min_R1 1 SGSGSESTGAEER 13 0 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 S(0.939)GS(0.061)GSESTGAEER 111.72 0.00053497 1866100.0 2881.4 2701.4 2174.0 660.25 1048.9 3470.6 1114.8 1089.1 2086.0 1113.1 True False 2840.3107076159567 2695.14507427352 1995.2621118826821 708.8069875294337 987.205764216743 3322.170528363746 1172.5188892417066 1139.7035619550238 1851.0527134461795 1305.4978518874802 2.175653298478779 2.064457685914149 1.5283534239431686 0.5429399876105849 0.7561910291843432 2.544753730203825 0.8981392711956488 0.873003015904812 1.4178902789996473 1.0 10.350384368453149 -5.376685739601022 3.5467884406201544 1.1671554185425232 2.1287917249446724 0.3495622834936051 0.5229862076864763 0.27645674243478763 6.28057076556848 0.14645444116869577 0.34242779626578357 4.200628362615106e-06 5.376685739601022 0.9616363064021491 S(ph)GSIVELIAGGGSSCSPVLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSIVELIAGGGSSCSPVLSR 21 0 P42858 P42858 HTT Huntingtin 1 S(0.5)GS(0.5)IVELIAGGGSSCSPVLSR 122.94 1.2572e-06 2520100.0 10866.0 7647.6 5454.4 7359.3 7413.2 8332.5 6567.1 5776.5 5731.2 4421.7 True False 12705.399186717399 8406.803186772346 5584.45358192719 6946.982280172517 5960.636676101469 7895.529031472083 5945.016746313311 5624.872995707663 5815.007957634837 5223.319207842057 2.4324378199291523 1.6094752880794168 1.069138867397371 1.3299938226525825 1.1411587993995151 1.511592287834542 1.1381683771858573 1.076877129634875 1.113278305661359 1.0 12.350751157144765 -4.81667835463125 2.3900910631737173 1.1906591217160243 2.6700986271523885 0.8778983884854081 0.1434542013499184 0.1633921923849271 1.2292931029984988 0.03776658258879614 0.4941287177970866 1.5251819094781849e-05 4.81667835463125 1.4794395054363643 up S(ph)GSLRRSS(ph)MS(ph)LYTAASVIDT(ph)ASK ddPTM_PC-9_Lapatinib_30min_R1 1 SGSLRRSSMSLYTAASVIDTASK 23 2 Q96PE2;A0A2R8Y4D7 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 4 S(0.645)GS(0.346)LRRS(0.365)S(0.612)MS(0.597)LY(0.213)T(0.225)AAS(0.269)VIDT(0.585)AS(0.142)K 40.254 0.045939 13878000.0 15628.0 31766.0 25085.0 10627.0 28152.0 18847.0 17132.0 20757.0 20536.0 9495.7 True False 15405.141854175798 31692.447778697235 23022.608130900244 11408.545030632768 26496.15470896154 18040.957744502834 18019.0111324802 21721.445997153998 18223.019426333038 11137.019092775085 1.3832374467391881 2.8456849642340174 2.067214569636115 1.0243804859806545 2.3791065174836943 1.6199090254057784 1.6179384252083815 1.9503823973189869 1.6362564591592423 1.0 13.443075515678435 -11.423837290563124 0.1793272233061814 2.5209996991189416e-11 2.120969868246109 0.22666376019234658 0.4822953021977255 53.11244239593122 1.4364522733330967 24.88933557290935 1.7917088022052472 3.768449583787937e-12 11.423837290563124 2.120969868220899 S(ph)GSMDPSGAHPSVR ddPTM_PC-9_AZD4547_30min_R2 1 SGSMDPSGAHPSVR 14 0 Q07666;Q07666-3;Q07666-2 Q07666 KHDRBS1 KH domain-containing, RNA-binding, signal transduction-associated protein 1 1 S(0.781)GS(0.219)MDPSGAHPSVR 120.63 0.0012657 0.0 3038.9 4387.0 10127.0 24522.0 16047.0 13056.0 6820.2 16238.0 8665.7 12682.0 True False 4005.2069869532957 5805.011957539221 9992.70936313575 18868.83176112331 13819.151041382573 12239.606256068642 7427.184587521902 13728.79021211915 9123.751210622826 12238.007040100381 0.32727608129570446 0.4743429169894975 0.8165307742014328 1.5418222672446298 1.1291994681896524 1.000130676176523 0.6068949432031853 1.1218158452707132 0.7455258998239626 1.0 13.579081013767343 -5.314631271582818 3.4210512119612746 1.0203858176597695 0.3794667090641978 0.5153905920601929 0.23648668597824662 0.19276761256016156 4.522948971225468 0.06696503531698976 0.16976243007870961 4.845836183076756e-06 5.314631271582818 -0.6409191085955717 S(ph)GSMDPSGAHPSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSMDPSGAHPSVR 14 0 Q07666;Q07666-3;Q07666-2 Q07666 KHDRBS1 KH domain-containing, RNA-binding, signal transduction-associated protein 1 1 S(0.688)GS(0.312)MDPSGAHPSVR 106.54 0.00076253 5008000.0 2245.1 2656.6 16985.0 16387.0 27521.0 23078.0 13841.0 12050.0 16698.0 8528.7 True False 2625.1510872537474 2920.329691142244 17389.98681597121 15468.889517370806 22128.45761115153 21867.74905350288 12529.88027983776 11733.700268030361 16942.176660487596 10074.885796847944 0.2605638555302591 0.28986231209250096 1.7260728475365832 1.5353910534857322 2.196397860715672 2.170520787475773 1.243674671107229 1.1646484639757801 1.6816246855907955 1.0 13.298475864828257 -5.258306147763494 24.099914961281932 1.6237723119295522 0.2752127953385273 0.6641963890890197 0.3732623168686845 95.42849242968512 733991.7314625083 0.1022965306867044 0.24763863797219596 5.5168839976594346e-06 5.258306147763494 -1.348559516591025 S(ph)GSMDPSGAHPSVR ddPTM_PC-9_Lapatinib_30min_R1 2 SGSMDPSGAHPSVR 14 0 Q07666;Q07666-3;Q07666-2 Q07666 KHDRBS1 KH domain-containing, RNA-binding, signal transduction-associated protein 1 1 S(0.782)GS(0.218)MDPSGAHPSVR;S(0.757)GS(0.243)MDPSGAHPSVR 109.1 0.00035256 14193300.0 41424.0 25927.0 140277.0 33865.0 76643.0 121483.0 49749.0 71884.0 153073.0 47309.0 True False 40833.286163768775 25866.96762445012 128743.96654487895 36355.54507032828 72135.00942593567 116287.45528070467 52324.75979627352 75223.99306544382 135832.3068098501 55486.29761471994 0.7359165761482729 0.46618658545326846 2.3202839634181056 0.6552166324516763 1.3000508688977475 2.0957868929761645 0.9430212871581525 1.35572197640175 2.448033346052904 1.0 15.759843920309535 -5.22477602547108 24.97420268787452 1.4894338414280197 0.601051100128105 0.28729395355819676 0.5745469535532448 728.1515184552673 495997.2958041984 0.14093697880044043 0.3728605579832226 5.959694178818049e-06 5.22477602547108 -0.8883827412999147 S(ph)GSNGSVVSLEQQQK ddPTM_PC-9_AZD4547_30min_R2 1 SGSNGSVVSLEQQQK 15 0 Q2M1P5 Q2M1P5 KIF7 Kinesin-like protein KIF7 1 S(0.744)GS(0.256)NGSVVSLEQQQK 173.28 7.8229e-05 19288000.0 24363.0 23913.0 21153.0 31746.0 30452.0 28468.0 26531.0 27656.0 35837.0 34768.0 True False 32109.92721811944 31642.4096057979 20872.497398875323 24427.45017081074 26224.265439782022 26687.891459693787 28892.207602642684 23382.400671657066 37731.27065731448 33550.78290255557 0.9570544839856366 0.9431198579687299 0.6221165526747056 0.7280739242883687 0.7816290164061869 0.7954476513172801 0.8611485367288392 0.6969256347778408 1.124601794446963 1.0 15.034058811443048 -8.266316258837794 24.96170231471461 1.062300923888582 0.7962694159312045 0.5164910795619879 0.10220228354362969 352.0693163336516 1801989.7312185683 0.09201080567303188 0.0267276562327708 5.4160634204435255e-09 8.266316258837794 -0.2660315079573776 S(ph)GSNGSVVSLEQQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSNGSVVSLEQQQK 15 0 Q2M1P5 Q2M1P5 KIF7 Kinesin-like protein KIF7 1 S(0.997)GS(0.003)NGSVVSLEQQQK 155.26 0.00018967 15966000.0 36154.0 35856.0 29304.0 33580.0 36651.0 40535.0 36587.0 36359.0 36725.0 27439.0 True False 42274.15812595074 39415.546715951335 30002.718496038873 31698.621467828903 29469.499651404916 38409.27324221072 33121.214493058615 35404.614775544906 37262.033648125944 32413.473492995527 1.3042156106807277 1.2160235380040014 0.9256249103485434 0.9779458370815735 0.909174379529957 1.1849786247225516 1.0218347780658568 1.0922808005502946 1.1495847137820072 1.0 14.98430601059104 -5.079337369436383 5.129328674726686 1.0351944806687536 1.285871720148224 0.5441889644649909 0.08485439634844429 0.15225648262625155 6.906138105631714 0.022810552909726906 0.0666404148693022 8.330338143501895e-06 5.079337369436383 0.2506772394794703 S(ph)GSNGSVVSLEQQQK ddPTM_PC-9_Lapatinib_30min_R1 1 SGSNGSVVSLEQQQK 15 0 Q2M1P5 Q2M1P5 KIF7 Kinesin-like protein KIF7 1 S(0.906)GS(0.094)NGSVVSLEQQQK 122.96 4.1928e-05 17906000.0 28234.0 31948.0 26290.0 25460.0 29585.0 27875.0 27033.0 22526.0 22631.0 29180.0 True False 27831.377982518537 31874.026368879284 24128.537682334736 27332.413332070246 27844.868466347943 26682.85122979873 28432.63646651514 23572.64019520599 20082.05846500502 34223.724120094026 0.8132188620050761 0.9313430138996724 0.7050237314228457 0.7986393659602453 0.8136130471551803 0.7796594881423857 0.8307873323996695 0.6887806865345087 0.5867876445747204 1.0 15.062709137543246 -7.753506558212376 24.997891465640024 0.7283381202357024 0.8094282033972331 0.02307082681445527 0.11075003368704149 404.05573923288773 1273269.73867466 0.05065576298290789 0.02857410059056588 1.7639791267051112e-08 7.753506558212376 0.08109008316153066 S(ph)GSPAPETTNESVPFAQHSSLDSR ddPTM_PC-9_AZD4547_30min_R2 2 SGSPAPETTNESVPFAQHSSLDSR 24 0 O15047 O15047 SETD1A Histone-lysine N-methyltransferase SETD1A 1 S(0.5)GS(0.5)PAPETTNESVPFAQHSSLDSR;S(0.566)GS(0.431)PAPET(0.002)T(0.001)NESVPFAQHSSLDSR 188.86 6.7244e-21 31861000.0 7058.0 7100.8 46173.0 178632.0 79168.0 54538.0 21380.8 86361.0 30311.0 56423.0 True False 9302.297184480027 9395.994736287787 45560.71585109777 137451.15223688836 68176.88973915212 51127.730238470576 23283.649779902113 73015.89182835449 31913.177578867075 54447.6479438246 0.17084846702795145 0.1725693412134522 0.8367802388471258 2.524464461324411 1.2521549105205134 0.9390255074235844 0.4276337116329544 1.341029311379756 0.5861259169871383 1.0 15.732582107590405 -5.359915346074906 4.432731701561567 1.1651451755466344 0.17345990793401422 0.33838251212061343 0.5364182360419201 0.25060424295366424 8.26021709328229 0.15160582449095536 0.336303729951059 4.366009274504661e-06 5.359915346074906 -0.9916852676126202 S(ph)GSPAPETTNESVPFAQHSSLDSR ddPTM_PC-9_Lapatinib_30min_R1 1 SGSPAPETTNESVPFAQHSSLDSR 24 0 O15047 O15047 SETD1A Histone-lysine N-methyltransferase SETD1A 1 S(0.5)GS(0.5)PAPETTNESVPFAQHSSLDSR 163.32 4.957600000000001e-10 6053200.0 22941.0 15010.0 52233.0 25216.0 36167.0 45101.0 28724.0 28241.0 58732.0 23184.0 True False 22613.857133135833 14975.245267211652 47938.604365210755 27070.468758110084 34039.7281670578 43172.135365566006 30211.18817238858 29553.179958839242 52116.983684621744 27191.323509261834 0.8316570955228848 0.5507361663403705 1.763011070383611 0.9955553928402718 1.251859923459161 1.5877173228019164 1.1110598629779138 1.086860665269674 1.9166769748030028 1.0 14.730858754294923 -5.243875637405376 24.81922281276172 1.3275456126111118 0.6911965382248902 0.40827177246288815 0.31175006586049675 709.2657360734083 1002255.2336741224 0.07524737486162263 0.19808538687682892 5.703275653100302e-06 5.243875637405376 -0.6363490743862216 S(ph)GSPISSEER ddPTM_PC-9_AZD4547_30min_R2 1 SGSPISSEER 10 0 H8Y6P7;P0CAP2-3;P0CAP2;P0CAP2-2;P0CAP1-11 H8Y6P7 GCOM1;POLR2M;MYZAP DNA-directed RNA polymerase II subunit GRINL1A;Myocardial zonula adherens protein 1 S(0.722)GS(0.278)PISSEER 111.27 0.0016202999999999999 26952000.0 19942.0 17830.0 25438.0 30165.0 25532.0 22453.0 21388.0 16058.0 26696.0 20132.0 True False 26283.14118063203 23593.19881534633 25100.675499106066 23210.925294604207 21987.322514400174 21049.01036056291 23291.490565953853 13576.605076130645 28107.09605903582 19427.184807703903 1.3529052943486375 1.2144424963719078 1.2920387460952307 1.1947652490236182 1.1317811989764488 1.0834822733665388 1.1989122869062092 0.6988457262601839 1.4467920255687212 1.0 14.245789234758668 -6.155753385204785 0.9932594593583194 1.0641702333175649 1.2997676317512616 0.19702594655960182 0.1763901637485427 0.87841444003403 1.8064557090044082 0.07430013948196666 0.13143958897376437 6.986290090266167e-07 6.155753385204785 0.23559739843369676 S(ph)GSPISSEERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSPISSEERR 11 1 H8Y6P7;P0CAP2-3;P0CAP2;P0CAP2-2;P0CAP1-11 H8Y6P7 GCOM1;POLR2M;MYZAP DNA-directed RNA polymerase II subunit GRINL1A;Myocardial zonula adherens protein 1 S(0.573)GS(0.426)PISSEERR 77.64399999999999 0.030081999999999998 0.0 20173.0 16790.0 15321.0 21499.0 22216.0 21768.0 14761.0 25046.0 20401.0 14826.0 True False 23587.890465088356 18456.800238755666 15686.310745216057 20294.480730698426 17862.934278890396 20626.44775962609 13362.731219614567 24388.569038430567 20699.32603009988 17513.836437448575 1.346814591385133 1.0538410761499872 0.8956524631961932 1.1587684287894913 1.01993268823131 1.1777229868107049 0.7629813871643794 1.392531506476916 1.181884169355379 1.0 14.096207522888738 -7.796740918496362 24.999891444504904 1.215405417665519 1.0597321841186578 0.10374694812234109 0.17367944636018393 361.23196428898495 255813.19987176618 0.09066025845719408 0.043554567274166456 1.596831464472961e-08 7.796740918496362 -0.15567323354686113 S(ph)GSPRPTEPTDFLMLFEGSPSGK ddPTM_PC-9_AZD4547_30min_R2 1 SGSPRPTEPTDFLMLFEGSPSGK 23 1 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 S(0.521)GS(0.224)PRPT(0.127)EPT(0.127)DFLMLFEGSPSGK 55.228 0.014653 1360600.0 3975.4 3920.8 5988.5 6517.0 8576.9 4387.6 4747.7 5928.5 5759.0 4832.1 True False 5239.4945065432 5188.121924577112 5909.088577183609 5014.606336646303 7386.145483070614 4113.242678395128 5170.2361024863985 5012.386548377167 6063.40898276848 4662.929649776772 1.1236486286671792 1.1126313957632799 1.2672480652729758 1.0754196853230173 1.5840139221110083 0.8821155340810344 1.1087956479750694 1.0749436351923356 1.3003432258641847 1.0 12.187020948377253 S(ph)GSPSDNSGAEEMEVSLAKPK ddPTM_PC-9_Lapatinib_30min_R1 2 SGSPSDNSGAEEMEVSLAKPK 21 1 P31749-2;P31749 P31749-2 AKT1 RAC-alpha serine/threonine-protein kinase 1 S(0.437)GS(0.437)PS(0.125)DNSGAEEMEVSLAKPK;S(0.511)GS(0.444)PS(0.038)DNS(0.007)GAEEMEVSLAKPK 101.92 7.3249e-05 16001600.0 70359.0 53389.0 51214.0 46455.0 56035.0 55552.0 45236.0 47753.0 59459.0 46594.0 True False 69355.66775773953 53265.381050710384 47003.382611757006 49871.45566933712 52739.131469048734 53176.17045803689 47578.09873855208 49971.7787108973 52762.10128897237 54647.710817397594 1.2691413184623193 0.9747047086509042 0.8601162227785953 0.9125991724700038 0.9650748527284835 0.9730722415019766 0.8706329693760047 0.9144349866342129 0.9654951781104631 1.0 15.737873442481218 -4.770320938245643 4.019003557306671 0.9285443357016933 1.303145041243361 0.8453954984020505 0.04285485223245023 0.08378629136387489 2.564540990608624 0.010773660191476696 0.09307012425265068 1.6969891350200314e-05 4.770320938245643 0.3746007055416677 S(ph)GSQPACLDHMQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSQPACLDHMQDR 14 0 O75815;O75815-3 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 S(0.5)GS(0.5)QPACLDHMQDR 64.26 0.028879000000000002 3036100.0 12389.0 18660.0 21665.0 19317.0 27430.0 18928.0 19651.0 18243.0 16406.0 15107.0 True False 14486.213006096246 20512.441480356196 22181.57576497004 18234.73111655899 22055.288407902575 17935.38235916036 17789.5150190804 17764.140580056264 16645.90671289734 17845.7795130538 0.8117444797241777 1.1494281583694224 1.2429591965284956 1.0217951590862522 1.235882601360709 1.0050209544526212 0.9968471820503979 0.9954253086597972 0.9327643379613214 1.0 14.12329529999243 -6.973629046430733 24.983624990239644 0.9837430731420358 1.102025780434373 0.1741521946549729 0.11571445858999578 366.814184224299 347515.5944168725 0.04044819272065423 0.03567103706316888 1.0626027941549251e-07 6.973629046430733 0.11828270729233714 S(ph)GSSPEVDSK ddPTM_PC-9_Lapatinib_30min_R1 1 SGSSPEVDSK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.886)GS(0.054)S(0.054)PEVDS(0.005)K 72.547 0.030277 6861900.0 20234.0 13731.0 14839.0 19723.0 17749.0 15079.0 17518.0 20224.0 19532.0 28344.0 True False 19945.459449538837 13699.206713130125 13618.994700196472 21173.49521399926 16705.038715876603 14434.106320865825 18424.9963237677 21163.680871341825 17332.10047892176 33243.222633994 0.5999857375182068 0.41209021351382247 0.40967733032807413 0.6369266736597183 0.5025096062375821 0.4341969633866282 0.5542482005016741 0.6366314452829304 0.5213724514541567 1.0 15.020772624856306 -14.189378554590327 0.2563148154607701 3.5076024034238293 0.479881963931828 0.7687457430316523 0.07915866844032735 73.15540291984773 0.845351390143267 95.84439510011013 0.10945923562734063 6.465787769695785e-15 14.189378554590327 -3.0277204394920014 S(ph)GSSPGLR ddPTM_PC-9_AZD4547_30min_R2 2 SGSSPGLR 8 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.461)GS(0.461)S(0.078)PGLR;S(0.985)GS(0.01)S(0.005)PGLR 92.051 0.0082649 65534000.0 55397.0 50887.0 79267.0 107910.0 98965.0 86229.0 64610.0 81702.0 62235.0 77720.0 True False 73012.09367081888 67335.22760047832 78215.86778786228 83033.01669288057 85225.41801024633 80837.08699866278 70360.16483384512 69076.83322518539 65524.61504472934 74999.04645612705 0.9735069593655368 0.897814449412608 1.0428914964087845 1.1071209650839124 1.136353354306998 1.0778415302379993 0.9381474586480831 0.9210361529808777 0.8736726417323177 1.0 16.194584632734475 -7.338961922229369 6.158397409806118 0.9251132049400951 1.0403379233346863 0.3570585519212649 0.0694547468685489 0.29594334527989813 18.853351734194337 0.033659686241203336 0.02254691834784354 4.581820571223891e-08 7.338961922229369 0.11522471839459125 S(ph)GSSPGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGSSPGLR 8 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.808)GS(0.163)S(0.029)PGLR;S(0.91)GS(0.074)S(0.015)PGLR 90.601 0.009352899999999999 117320000.0 95132.0 107914.0 121354.0 115043.0 133438.0 127635.0 128782.0 104768.0 128343.0 94340.0 True False 111235.96865735293 118626.98874121954 124247.5395976076 108597.51368443812 107291.78179269763 120941.59591142395 116582.83665906101 102017.95101087185 130219.77357389846 111443.09520497076 0.9981414142595657 1.0644624372917484 1.11489670462837 0.97446605807835 0.9627494785151305 1.0852318458042032 1.0461198735070758 0.9154263960744828 1.1684866912067802 1.0 16.765947707255755 -5.770452844895752 24.993811070102904 1.0194570366939353 1.0596964171103573 0.05419157241899508 0.07109625212363481 575.9006629203062 1596941.7691361632 0.01949126481329514 0.029391492364902037 1.6964737930777245e-06 5.770452844895752 0.040239380416422055 S(ph)GSSPGLR ddPTM_PC-9_Lapatinib_30min_R1 1 SGSSPGLR 8 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.897)GS(0.097)S(0.006)PGLR 101.72 0.0044989 13675000.0 49973.0 49934.0 61826.0 47377.0 51332.0 47863.0 38665.0 44195.0 50108.0 38331.0 True False 49260.375856074206 49818.38089093581 56742.90493526159 50861.26262503897 48312.75268259495 45816.011064102466 40666.884510702 46248.46104177968 44464.30937936773 44956.462277152976 1.095735148206012 1.1081472688800444 1.2621746031848802 1.131344862313306 1.0746564617284766 1.019119582445132 0.9045837339244786 1.0287388886754842 0.9890526773492282 1.0 15.456240890730642 -6.574062817628508 2.1022547535901603 0.9821023879998032 1.154421844668171 0.6863719430689081 0.05169018062751994 0.1883725475264366 1.6883162898474195 0.020062922648730643 0.020925045640432755 2.666472950153171e-07 6.574062817628508 0.1723194566683679 S(ph)GSSQELDVKPSASPQER ddPTM_PC-9_Lapatinib_30min_R1 2 SGSSQELDVKPSASPQER 18 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.442)GS(0.442)S(0.116)QELDVKPSASPQER;S(0.435)GS(0.131)S(0.435)QELDVKPSASPQER 81.37899999999999 0.0014866 99516000.0 70049.0 85946.0 87087.0 81690.0 76914.0 65429.0 81582.0 77239.0 84170.0 57913.0 True False 69050.08841458666 85746.99731750629 79927.04302554167 87697.7551098513 72390.06973874201 62630.75419244845 85805.9167762082 80827.80591483228 74689.88825060631 67923.18488577812 1.0165908523091722 1.262411317456643 1.1767269623759493 1.2911313752046045 1.0657637721269335 0.9220821181717318 1.263278759977205 1.189988456088374 1.0996228809972222 1.0 16.051616487309538 -6.292781757115143 24.96876839085499 1.099877862526884 1.1914086086753872 0.14981501914204742 0.1110555483941456 1419.2411771781578 1130628.067424937 0.03540936043782699 0.04015412239257972 5.095868857606589e-07 6.292781757115143 0.09153074614850332 S(ph)GSTGSSLSVSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSTGSSLSVSVR 13 0 Q5TH69 Q5TH69 ARFGEF3 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 1 S(0.65)GS(0.175)T(0.175)GSSLSVSVR 131.79 6.3973e-05 7412400.0 13676.0 11840.0 10864.0 10639.0 17220.0 17246.0 17740.0 17524.0 16289.0 12073.0 True False 15991.076686687573 13015.396952165995 11123.038961949442 10042.93132210338 13845.864614804319 16341.589400152132 16059.538773522265 17064.013568212795 16527.195809239583 14261.739330184588 1.1212571143298693 0.912609370486758 0.7799216283814576 0.7041869921747754 0.970839831962145 1.145834250775121 1.1260575166685793 1.1964889536367607 1.158848540602633 1.0 13.799862319957464 -6.6233920650850875 4.049532488298638 1.1373138954579294 0.8708479220000206 0.5185396197769419 0.11162153660136963 0.1786611128279142 5.4351162441626535 0.040156929355854944 0.04013921889747245 2.3801697694435026e-07 6.6233920650850875 -0.2664659734579088 S(ph)GSTGSSLSVSVR ddPTM_PC-9_Lapatinib_30min_R1 1 SGSTGSSLSVSVR 13 0 Q5TH69 Q5TH69 ARFGEF3 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 1 S(0.77)GS(0.229)T(0.001)GSSLSVSVR 114.87 0.00029815 8181100.0 16637.0 16079.0 14777.0 15331.0 15082.0 16552.0 15571.0 18321.0 21050.0 13763.0 True False 16399.753329147854 16041.77006339082 13562.092100869551 16458.492882716757 14194.906412352855 15844.109544596531 16377.190190511872 19172.26054409879 18679.12733367309 16141.916211955242 1.0159731418381202 0.993795894660248 0.8401785712916173 1.0196120873510077 0.8793817429085423 0.9815507240002804 1.0145753438109397 1.1877313877951599 1.157181532130535 1.0 13.978524231113763 -7.552559483580793 3.668433186840912 1.1286790067667563 0.9528795198238389 0.4971376562923612 0.07107647658576154 0.1702025211416402 4.91643297181849 0.03450761303632874 0.019544571006059875 2.8018218410366535e-08 7.552559483580793 -0.17579948694291736 S(ph)GSVSNYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSVSNYR 8 0 Q13131;Q13131-2 Q13131 PRKAA1 5-AMP-activated protein kinase catalytic subunit alpha-1 1 S(0.627)GS(0.373)VSNYR 115.7 0.0036225000000000003 36567000.0 87386.0 76032.0 61694.0 73710.0 101420.0 90263.0 92784.0 118970.0 81769.0 84006.0 True False 102178.72384782691 83579.9544820172 63165.01893579793 69580.26767104416 81547.4790495619 85529.44938106994 83994.82782201206 115847.1635591346 82964.7169332502 99235.62280886967 1.0296577071383504 0.8422374155195692 0.6365155691868369 0.7011622006449995 0.8217561067422775 0.8618825272634387 0.8464181051575423 1.1673949362141776 0.8360376504417406 1.0 16.59857048024525 -7.5485132428997 23.6954741840491 1.0024114096639474 0.8079002497991565 0.31760662708207676 0.12211994450702116 148.30084653597882 137080.14577888214 0.059011706184897414 0.03407248464813232 2.8280478743419274e-08 7.5485132428997 -0.19451115986479084 S(ph)GSVSNYR ddPTM_PC-9_Lapatinib_30min_R1 1 SGSVSNYR 8 0 Q13131;Q13131-2 Q13131 PRKAA1 5-AMP-activated protein kinase catalytic subunit alpha-1 1 S(0.63)GS(0.37)VSNYR 112.85 0.0037234 39000000.0 50062.0 40246.0 53364.0 45226.0 55408.0 55775.0 55602.0 50807.0 76329.0 66198.0 True False 49348.106699753545 40152.81285970686 48976.61791099702 48552.07090951331 52149.010376319275 53389.63326787534 58480.79949732458 53167.67870007241 67732.02423999691 77640.23609670975 0.6355996475627002 0.5171650020447125 0.6308149018247583 0.6253467705718486 0.6716750617728898 0.6876541848916131 0.7532279966856372 0.6847954278996011 0.8723830277335707 1.0 16.24451688470863 -8.405479174539652 0.2999734989656551 1.0550909901646788 0.546723617227318 0.8805801259228094 0.04519624537819181 0.5675445113717964 0.16505633484350285 0.10579885176097918 0.0676869979276956 3.931160953136101e-09 8.405479174539652 -0.5083673729373608 S(ph)GSVYEPLK ddPTM_PC-9_AZD4547_30min_R2 1 SGSVYEPLK 9 0 Q93100-4;Q93100-2;I3L3F2;H3BV13;H3BQ89;Q93100-3;Q93100 Q93100-4;Q93100-3 PHKB Phosphorylase b kinase regulatory subunit beta 1 S(0.794)GS(0.206)VYEPLK 103.31 0.0028964000000000004 38348000.0 123040.0 146640.0 140250.0 214150.0 187830.0 133410.0 135300.0 213700.0 164750.0 189800.0 True False 162164.1606090143 194038.51229850753 138390.1933622778 164781.02608451832 161753.04668180246 125067.85161015026 147341.43788916947 180677.57533747182 173458.34865620904 183155.15977062355 0.8853922587389973 1.05942149018086 0.7555899246059589 0.8996799560049726 0.883147637688044 0.6828519151018209 0.8044623917431221 0.9864727565619524 0.9470568499049744 1.0 17.482706819057597 -7.77258816836283 24.985462752143704 0.975073653744388 0.8535510631925155 0.26874696619147065 0.09438263830522338 335.5558507706151 751999.6932791767 0.05403811840663098 0.026337603194884956 1.6881531040266356e-08 7.77258816836283 -0.12152259055187253 S(ph)GSYSLPR ddPTM_PC-9_Lapatinib_30min_R1 1 SGSYSLPR 8 0 Q9BW04 Q9BW04 SARG Specifically androgen-regulated gene protein 1 S(0.838)GS(0.02)Y(0.001)S(0.142)LPR 72.87899999999999 0.031477 23150000.0 38035.0 26414.0 34669.0 32532.0 33882.0 32931.0 30105.0 28136.0 34399.0 28699.0 True False 37492.613925235266 26352.840005871338 31818.64864621011 34924.511803570655 31889.127374574982 31522.61789591039 31663.68959510371 29443.30127551788 30524.62238247131 33659.58391098626 1.1138763338366144 0.7829223342618312 0.9453072483116679 1.0375800216642468 0.9474011163924873 0.936512405479309 0.9407035356954874 0.8747375295363585 0.9068627367229065 1.0 15.038729722192743 -7.095456129586496 2.13515384503009 0.9192915014708328 0.9574960368213181 0.029273150084305644 0.08403198466261508 1.3344977218445906 12.000990827577642 0.037744195136282126 0.02759746723177822 8.026826400534146e-08 7.095456129586496 0.03820453535048529 S(ph)GTATPQR ddPTM_PC-9_AZD4547_30min_R2 2 SGTATPQR 8 0 Q13131;Q13131-2 Q13131 PRKAA1 5-AMP-activated protein kinase catalytic subunit alpha-1 1 S(0.971)GT(0.028)AT(0.001)PQR;S(0.994)GT(0.005)AT(0.001)PQR 87.806 0.011448999999999999 8176800.0 11604.599999999999 11259.6 14195.9 19166.5 14340.8 16233.9 12731.9 18328.9 15479.3 21102.6 True False 15294.621409325151 14899.04550652123 14007.65309056371 14747.95954447313 12349.82746022678 15218.791666696754 13865.01443504152 15496.58966122125 16297.504196382717 20363.804397131546 0.7510689609393203 0.7316435188613339 0.6878701453514665 0.724224180161077 0.6064597370600545 0.7473452096623202 0.680865626316591 0.7609869628979595 0.8003172628528288 1.0 14.313719492640386 -8.731751630582746 1.133980123323376 0.9995002594905678 0.7026548673507954 0.8250161182089544 0.040857006999004526 0.3048391435894637 0.7648212841002309 0.03848269281683346 0.012042203447087781 1.854591945964726e-09 8.731751630582746 -0.29684539213977235 S(ph)GTATPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SGTATPQR 8 0 Q13131;Q13131-2 Q13131 PRKAA1 5-AMP-activated protein kinase catalytic subunit alpha-1 1 S(0.983)GT(0.013)AT(0.004)PQR;S(0.922)GT(0.076)AT(0.002)PQR;S(0.965)GT(0.035)ATPQR 81.525 0.017759999999999998 14803300.0 10317.8 14492.2 17054.7 13463.7 29077.0 25780.5 15072.8 17720.2 23293.7 22978.7 True False 12064.399754160933 15930.889840386824 17461.348728309935 12709.372538904337 23379.57058099099 24428.525196023533 13644.995266378051 17255.063526103866 23634.326295149123 27144.55641071089 0.4444500610590371 0.586890778369865 0.6432725760594825 0.4682107287592065 0.8612986790885893 0.8999419561847897 0.5026788819062784 0.6356730706896077 0.8706838283724292 1.0 14.728375287461715 -8.324767506877212 0.07292658680706934 1.5482875788654216 1.1384567278817554e-10 0.47256711513138216 0.13827100693258434 23.195496582665154 1.388037078330911 15.034422398598371 13.2761402535746 4.734046212955751e-09 8.324767506877212 -1.548287578751576 S(ph)GTATPQR ddPTM_PC-9_Lapatinib_30min_R1 2 SGTATPQR 8 0 Q13131;Q13131-2 Q13131 PRKAA1 5-AMP-activated protein kinase catalytic subunit alpha-1 1 S(0.991)GT(0.009)ATPQR;S(0.991)GT(0.008)ATPQR 128.28 0.0036853000000000003 8879600.0 12534.6 16055.9 17024.7 14413.1 20628.6 13983.2 18638.5 18941.2 21305.7 11956.9 True False 12355.854305435878 16018.723550021552 15624.99488324246 15473.087454692128 19415.266305388028 13385.171132431271 19603.510331119076 19821.277300250204 18906.027707032725 14023.634233432223 0.8810736289726973 1.1422662116951863 1.1141901323975354 1.1033578883428392 1.384467534036377 0.9544723507206954 1.3978908751331003 1.4134194439410326 1.3481546503802073 1.0 13.775572652658067 -3.6419530590081166 0.4902823383959919 1.2758415718363947 6.921995634534289e-12 0.290136266999133 0.1589520443169175 16.100443954264293 1.258742992337417 0.09320904642325673 15.078251645536522 0.0002280588557526224 3.6419530590081166 -1.2758415718294727 S(ph)GTNSPPPPFSDWGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGTNSPPPPFSDWGR 15 0 D6RAU6;D6REP2;D6RAJ6;Q9UKT5-2;Q9UKT5 D6RAU6 FBXO4 F-box only protein 4 1 S(0.723)GT(0.23)NS(0.047)PPPPFSDWGR;S(0.689)GT(0.203)NS(0.109)PPPPFSDWGR 147.51 6.1004999999999994e-06 52055000.0 227300.0 226690.0 230650.0 249900.0 274350.0 246610.0 254240.0 236380.0 224910.0 200809.0 True False 265777.40062036295 249194.28505798226 236149.57074499576 235898.91318673154 220593.08693795392 233677.33746790665 230156.54666179864 230175.27546531273 228198.88326208355 237214.08209683112 1.120411563559166 1.0505037595376012 0.9955124445293225 0.9944557721933105 0.9299325107010616 0.9850904946381692 0.9702482442330234 0.970327197402028 0.9619955158013446 1.0 17.855830131741563 -4.823148140290155 1.1580019539948456 0.9694400773459865 1.1863787172288933 0.8725775425181901 0.017988892756172204 0.4607308498191507 0.5444250476313691 0.005405413647835241 0.11988816742618448 1.5026293233496758e-05 4.823148140290155 0.21693863988290685 S(ph)GTNSPPPPFSDWGR ddPTM_PC-9_Lapatinib_30min_R1 2 SGTNSPPPPFSDWGR 15 0 D6RAU6;D6REP2;D6RAJ6;Q9UKT5-2;Q9UKT5 D6RAU6 FBXO4 F-box only protein 4 1 S(0.684)GT(0.275)NS(0.041)PPPPFSDWGR;S(0.818)GT(0.177)NS(0.005)PPPPFSDWGR 189.33 2.104e-07 66622000.0 273980.0 243540.0 280710.0 257410.0 256560.0 273870.0 231520.0 243690.0 264310.0 208660.0 True False 270072.9949582216 242976.098093053 257631.10737193536 276340.7900945877 241469.64521636727 262157.2185221518 243506.97276394002 255012.7270340834 234540.62449231034 244726.60297802673 1.103570235813189 0.9928471001367559 1.052730288562324 1.1291816530440686 0.9866914437497754 1.0712248498202304 0.9950163562144643 1.0420310825667785 0.9583781315077096 1.0 17.900811412381906 -7.492717311408284 0.9141500156193804 0.9878659329470736 1.0572320747292896 0.27448815708543206 0.045087268604799856 0.848980464803694 1.317800742169294 0.03645092603115953 0.01784624507613489 3.215753037947917e-08 7.492717311408284 0.069366141782216 S(ph)GTPPRQGSITSPQANEQSVTPQR ddPTM_PC-9_AZD4547_30min_R2 2 SGTPPRQGSITSPQANEQSVTPQR 24 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.474)GT(0.432)PPRQGS(0.076)IT(0.014)S(0.005)PQANEQSVTPQR;S(0.472)GT(0.418)PPRQGS(0.094)IT(0.009)S(0.007)PQANEQSVTPQR 62.683 0.0011755000000000001 22715700.0 6497.0 4859.34 8758.9 12225.0 10688.2 9196.5 8220.3 9910.8 9190.699999999999 8364.6 True False 8562.910854004922 6430.026625427092 8642.751263036404 9406.715124367201 9204.327921761396 8621.441401189903 8951.890775168808 8379.313587527433 9676.50163881407 8071.757899986093 1.0608483257432282 0.796607963853595 1.0707396542519312 1.1653861824056204 1.1403126847718332 1.0680996020959395 1.1090385621184489 1.038102689817031 1.198809696563216 1.0 12.97866718832744 -5.4594523683765015 9.600810427677265 1.1058080473086407 0.9294033115076977 0.41834230459534705 0.08094168050196264 0.4241719984436093 62.03197748642356 0.01955292986707534 0.04067947535795842 3.47174350447345e-06 5.4594523683765015 -0.17640473580094296 S(ph)GTPPRQGSITSPQANEQSVTPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SGTPPRQGSITSPQANEQSVTPQR 24 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.536)GT(0.451)PPRQGS(0.01)IT(0.002)S(0.001)PQANEQSVTPQR;S(0.535)GT(0.462)PPRQGS(0.003)ITSPQANEQSVTPQR;S(0.439)GT(0.377)PPRQGS(0.179)IT(0.004)S(0.001)PQANEQSVTPQR 79.67 7.7652e-05 31097200.0 25541.0 16017.3 21867.7 30022.100000000002 31847.9 33989.6 28353.8 31658.0 25241.2 22646.800000000003 True False 29864.586842255558 17607.391689352047 22389.108901714088 28340.059069961466 25607.532617063072 32207.125540728928 25667.92280026471 30827.011044423656 25610.304798341105 26752.485568029853 1.1163294254028033 0.6581590949587686 0.8368982704347235 1.0593430280672245 0.9572019972478729 1.203892829278546 0.9594593644389726 1.152304557497379 0.9573056205643301 1.0 14.707385317795268 -5.7615354037102415 24.999987714249656 1.0475575550915897 0.8492319093265975 0.2600658894258734 0.13034037483767325 2.8465989880970493 741441.937669483 0.03404424793034233 0.054367268384351554 1.7316678593361472e-06 5.7615354037102415 -0.19832564576499212 S(ph)GTPPRQGSITSPQANEQSVTPQR ddPTM_PC-9_Lapatinib_30min_R1 1 SGTPPRQGSITSPQANEQSVTPQR 24 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.516)GT(0.466)PPRQGS(0.011)IT(0.004)S(0.002)PQANEQSVTPQR 58.457 0.0026355999999999997 8582300.0 1428.5 760.37 1634.1 1234.4 3105.5 3380.2 2766.5 1419.1 918.39 1196.4 True False 1408.1293280451828 758.6094099819938 1499.7506058084134 1325.1818938376864 2922.840595647911 3235.636725631055 2909.7358334115393 1485.0365666792518 814.951247124562 1403.1961458972075 1.0035156753832308 0.5406296277253076 1.0688103799269408 0.9444024612755485 2.082987901722776 2.305904798193541 2.0736486783542625 1.0583242913126127 0.5807821305007076 1.0 10.454500974969983 -6.122867367800315 7.407300925332182 1.5862279382610422 0.8656664421057285 0.2471036545759323 0.5293617768777755 0.3814770557757463 21.441101446679006 0.1727548481165045 0.22387011611937999 7.535856713422403e-07 6.122867367800315 -0.7205614961553137 S(ph)GTPTQDEMMDKPTSSSVDTMSLLSK ddPTM_PC-9_AZD4547_30min_R2 2 SGTPTQDEMMDKPTSSSVDTMSLLSK 26 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 S(0.419)GT(0.367)PT(0.137)QDEMMDKPT(0.039)S(0.011)S(0.011)S(0.011)VDT(0.003)MSLLSK;S(0.367)GT(0.331)PT(0.088)QDEMMDKPT(0.033)S(0.044)S(0.056)S(0.073)VDT(0.006)MS(0.002)LLSK 65.899 0.00034388 5300500.0 21330.5 19859.2 21817.7 30942.0 28585.0 22510.0 19041.5 27649.0 16238.5 30665.0 True False 28113.15529803789 26278.298032177565 21528.383042568057 23808.79994913456 24616.46616301618 21102.44614155217 20736.15661172669 23376.482360813054 17096.83395844521 29591.427683699578 0.9500438977982806 0.888037519279712 0.7275209318280698 0.8045843615125615 0.8318782867166679 0.7131270031008488 0.7007487720218781 0.7899748065785274 0.5777630650738421 1.0 14.852891682789819 -5.1059503376042334 3.6516180948616097 0.7600174436943864 0.9406540192220794 0.260193015404649 0.1030046000261582 0.2835503470047039 6.687664069434869 0.02522110613199084 0.08459882515647836 7.83519234550645e-06 5.1059503376042334 0.18063657552769297 S(ph)GVSITIDDPVR ddPTM_PC-9_AZD4547_30min_R2 1 SGVSITIDDPVR 12 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-3;Q9UKV3-2;G3V3B0;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 S(0.928)GVS(0.072)ITIDDPVR 105.65 0.0017652000000000002 3047900.0 19717.0 20120.0 25215.0 31194.0 27363.0 32902.0 26503.0 35223.0 28294.0 28048.0 True False 25986.595860922756 26623.396531955594 24880.632624811667 24002.705242495747 23564.119769760764 30844.632738753888 28861.71565688588 29780.09469401853 29789.563076654165 27066.04805714678 0.9601178497154483 0.9836455058286832 0.9192562051275138 0.8868197230647361 0.8706154559397771 1.1396060730265856 1.0663439152974146 1.100274950784886 1.1006247758725989 1.0 14.724196633021304 -6.7617697096584335 24.999999929931757 1.0866980083499853 0.9250603078096553 0.7530673598895539 0.04497771834856641 4.4585299483197405 337416.07938489167 0.015853471071369127 0.014854606695288262 1.730733860250209e-07 6.7617697096584335 -0.16163770054033 S(ph)HEAEVLK ddPTM_PC-9_AZD4547_30min_R2 3 SHEAEVLK 8 0 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 S(1)HEAEVLK;S(1)HEAEVLK;S(1)HEAEVLK 133.75 0.0020202 61764200.0 272416.0 255329.0 327393.0 414908.0 393682.0 359299.0 322578.0 404988.0 340730.0 399299.0 True False 359038.62139519805 337859.1060192685 323051.5549052139 319257.3708646992 339026.049745969 336831.97673094436 351286.8170836109 342406.4102984177 358740.29218591825 385319.66354715626 0.9317941837952896 0.8768280936119954 0.8383988295102364 0.828551981816074 0.8798566017238263 0.8741624386104607 0.911676330893037 0.8886294749307888 0.9310199455782895 1.0 18.555696285604554 -8.63312817700714 0.6943765268735869 1.000806562077464 0.8682841273194993 0.6619723599151048 0.027636933498721296 0.5586436116394791 0.5945675667573097 0.029713701500758048 0.011497365294200835 2.3274042497689455e-09 8.63312817700714 -0.13252243475796466 S(ph)HEAEVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 9 SHEAEVLK 8 0 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 S(1)HEAEVLK;S(1)HEAEVLK;S(1)HEAEVLK;S(1)HEAEVLK;S(1)HEAEVLK;S(1)HEAEVLK;S(1)HEAEVLK;S(1)HEAEVLK;S(1)HEAEVLK 117.52 0.0020079 59095600.0 398716.0 480538.0 492261.0 539485.0 626575.0 504882.0 534153.0 557105.0 442942.0 394964.0 True False 466210.7438000389 528242.6368749943 503998.3691502393 509259.40448396857 503802.1266562725 478405.0991260349 483554.1609071731 542481.5840515387 449419.18878606433 466567.84666669654 0.9992346174962358 1.1321882565395822 1.08022525073461 1.0915012856592532 1.0798046420377851 1.02537091345644 1.0364069542336276 1.1627067487123108 0.9632450928559534 1.0 18.831727362442905 -6.697767850333825 12.01485112652738 1.0476520145381858 1.0807401284475489 0.08959944550616572 0.05715125573552212 2.0648886527499113 383.70757101988926 0.018134268278481552 0.018128486680423665 2.005543793011145e-07 6.697767850333825 0.03308811390936306 S(ph)HEAEVLK ddPTM_PC-9_Lapatinib_30min_R1 5 SHEAEVLK 8 0 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 S(1)HEAEVLK;S(1)HEAEVLK;S(1)HEAEVLK;S(1)HEAEVLK;S(1)HEAEVLK 132.32 0.0018739000000000002 68448000.0 130650.0 229732.0 283047.0 265608.0 281331.0 275933.0 220995.0 232410.0 304827.0 293568.0 True False 128786.90704172455 229200.06966869158 259775.96825301627 285141.69836231327 264783.66369802685 264131.98882123956 232437.0397631603 243208.61705441878 270494.1732893858 344310.8376452276 0.3740425596896968 0.6656777673227227 0.754480951077948 0.8281519696342486 0.7690250632507122 0.7671323697727951 0.6750790691132985 0.7063635252312825 0.7856103953605396 1.0 18.39335206681995 -4.71110819427609 2.0154796764576957 0.7719977995120464 0.20742583144218107 0.6896520647469393 0.08328060269531586 0.5245500563090182 2.0083733805060473 0.02142698361764449 0.5872292089924916 1.9448755011846626e-05 4.71110819427609 -0.5645719680698653 S(ph)HESLLSPCSTVECLDLGR ddPTM_PC-9_AZD4547_30min_R2 2 SHESLLSPCSTVECLDLGR 19 0 Q9UJF2-2;Q9UJF2 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 S(0.982)HES(0.018)LLSPCSTVECLDLGR;S(0.887)HES(0.11)LLS(0.002)PCS(0.001)TVECLDLGR 156.06 3.3484999999999997e-20 0.0 1027.9 668.19 4604.3 11522.2 7347.0 6948.0 2357.77 9809.2 2831.67 7735.200000000001 True False 1354.750818351804 884.1693503323758 4543.243973603827 8865.934806215437 6326.995868451284 6513.540461639468 2567.6069623942894 8293.413532991694 2981.346295231121 7464.393002411642 0.18149510856597487 0.1184516075247797 0.6086555158786479 1.187763667233354 0.8476236267848062 0.8726148877122405 0.34398067753998635 1.1110633550929334 0.39940907375427437 1.0 12.865809231155104 -5.3791084928394755 3.9633478678905085 0.8157634855368533 0.1505022357582753 0.5113999042869248 0.2587382838955644 0.17385229797837143 4.674118019381314 0.06706416999885961 0.1513660222570591 4.177259998102415e-06 5.3791084928394755 -0.665261249778578 S(ph)HHAASTTTAPTPAAR ddPTM_PC-9_AZD4547_30min_R2 4 SHHAASTTTAPTPAAR 16 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 S(0.945)HHAAS(0.052)T(0.002)T(0.001)TAPTPAAR;S(0.998)HHAAS(0.001)TTTAPTPAAR;S(1)HHAASTTTAPTPAAR;S(1)HHAASTTTAPTPAAR 90.229 0.003074 25715000.0 27376.699999999997 20965.5 43454.1 66600.3 51171.3 50584.0 30626.8 50083.2 35711.5 49701.8 True False 36081.92112926528 27742.18787230193 42877.87024159546 51246.629799377726 44067.048275933164 47420.97448353065 33352.52586802672 42343.9922374434 37599.13698352781 47961.75511005051 0.7523061040296297 0.57842311668216 0.8940012754581264 1.0684894596077628 0.9187955731565546 0.9887247531855535 0.695398360454028 0.8828699479467154 0.7839399725313392 1.0 15.549596833177231 -5.277411632656381 23.0863803415102 0.9018191877400266 0.6653646480183429 0.43712719119220744 0.10830611341532986 244.29572614528635 353107.1659701458 0.02922339042850211 0.061239482295617306 5.279446185020877e-06 5.277411632656381 -0.23645453972168362 S(ph)HHAASTTTAPTPAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SHHAASTTTAPTPAAR 16 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 S(0.96)HHAAS(0.005)T(0.005)T(0.025)T(0.005)APTPAAR;S(1)HHAASTTTAPTPAAR;S(0.997)HHAAS(0.001)TT(0.001)T(0.001)APTPAAR 102.15 0.00087299 17225550.0 7363.5 9080.8 15795.199999999999 15960.900000000001 18865.3 19027.199999999997 20333.9 12578.599999999999 17670.0 16012.600000000002 True False 8609.99511424568 9982.28181108352 16171.817471629582 15066.662518935975 15168.779890689191 18029.380136528736 18407.725787312553 12248.425078128348 17928.39032164427 18915.55762432815 0.4551806129771177 0.5277286564496971 0.8549479636185972 0.7965222500000773 0.8019208416663297 0.9531508663186508 0.9731526901241097 0.6475318000868818 0.9478118846777089 1.0 14.207285686732131 -5.217666174624941 3.3996388378121596 0.8630957340116743 0.4663032425934205 0.6965900796757367 0.10073084548694178 0.1330249240437065 3.1294185129401275 0.026365711389346166 0.07941206303187945 6.05806355752886e-06 5.217666174624941 -0.3967924914182538 S(ph)HHAASTTTAPTPAAR ddPTM_PC-9_Lapatinib_30min_R1 1 SHHAASTTTAPTPAAR 16 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 S(0.998)HHAASTTT(0.001)APTPAAR 107.63 0.0005021 7195700.0 11738.0 7039.2 10614.0 7483.7 10092.0 9014.6 5757.4 6777.2 10412.0 5973.6 True False 11570.613967514435 7022.901164887161 9741.357891224832 8034.076262891363 9498.408401635395 8629.06657205896 6055.490000825446 7092.093453384978 9239.2909167793 7006.1288006783325 1.6514988942815567 1.0023939560185084 1.3904051964162685 1.146721176766477 1.3557284874231488 1.2316454375237142 0.864313256735896 1.012269921828774 1.3187440853049623 1.0 12.774401795552823 -7.023850837760017 21.23251404063364 1.0495861623094944 1.288356928745265 0.29442123118199914 0.18954780333995838 151.79548070084587 135130.34022627998 0.06838206948330015 0.05345328675964101 9.465622106159584e-08 7.023850837760017 0.23877076643577055 S(ph)HIASPSPCPDR ddPTM_PC-9_Lapatinib_30min_R1 1 SHIASPSPCPDR 12 0 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 1 S(0.785)HIAS(0.214)PSPCPDR 140.63 9.7834e-05 0.0 13399.0 14833.0 18514.0 14727.0 15460.0 17262.0 14054.0 12636.0 13563.0 14745.0 True False 13207.927802924334 14798.6550998368 16991.850386106722 15810.072707831827 14550.673195529458 16523.74449968738 14781.647353249864 13223.114689985929 12035.392115278293 17293.65360352249 0.7637442096234687 0.8557275078542402 0.9825483252796104 0.9142124082219112 0.8413880333861711 0.9554802518029915 0.8547440403362212 0.7646223865205993 0.6959427077241123 1.0 14.077955076687092 -7.55804402624062 6.837605417314516 0.7992478314994881 0.889296216900158 0.07800222253675737 0.09223087848755063 0.3555945964178012 49.273284447499236 0.042724257294937264 0.02472119864655232 2.7666611632286928e-08 7.55804402624062 0.09004838540066995 S(ph)HKS(ph)SEGS(ph)GKK ddPTM_PC-9_AZD4547_30min_R2 1 SHKSSEGSGKK 11 2 H0YCJ2;A0A0D9SF51;A0A0D9SG17;A0A1B0GWB6;A0A087WW73;A0A087WT80;Q9NQ66-2;Q9NQ66 H0YCJ2 PLCB1 Phosphoinositide phospholipase C;1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 3 S(0.904)HKS(0.628)S(0.488)EGS(0.98)GKK 65.092 0.024942 0.0 4943.6 5150.0 5440.5 8929.3 7482.9 5298.8 5031.2 7121.0 6745.1 6510.2 True False 6515.561966732147 6814.636786261 5368.3554152404495 6870.787841309777 6444.028499256033 4967.465198349917 5478.967053274129 6020.61307430105 7101.632215605429 6282.279879550658 1.037133348347125 1.0847394444241825 0.8545234402425927 1.0936774503910214 1.0257468025631713 0.7907105849453522 0.8721303664150051 0.9583484323738337 1.130422768766134 1.0 12.617072502062232 -5.2197814982298665 24.998451800070722 0.9613318414132318 1.060936449500703 0.124090513416106 0.10068279554117553 1061.7950344228004 637168.6062090273 0.026719660055103876 0.07069228576282682 6.028628214770947e-06 5.2197814982298665 0.09960460808747118 S(ph)HLDSPEAR ddPTM_PC-9_AZD4547_30min_R2 1 SHLDSPEAR 9 0 K7ER08;K7EP90;Q9BTD8-4;Q9BTD8-2;Q9BTD8-3;Q9BTD8 K7ER08 RBM42 RNA-binding protein 42 1 S(0.999)HLDS(0.001)PEAR 68.016 0.025046000000000002 2405700.0 6912.4 7571.9 12171.0 14028.0 15012.0 11704.0 11102.0 19655.0 12165.0 9807.1 True False 9110.399413148163 10019.368598425175 12009.604587609878 10794.06133043951 12927.842925982126 10972.147029796834 12090.056492576205 16617.771376967732 12808.017064660275 9463.756414048923 0.96266207777958 1.0587094764560347 1.269010323404103 1.1405683809037765 1.3660371590704485 1.1593860354973538 1.2775113774725377 1.7559381972573482 1.3533756052350212 1.0 13.20819722554539 -4.84198487918813 0.5477674296358475 1.369593258622899 0.7073527847446395 0.26352672052223725 0.18814033298684418 4.846332340422121 1.1630759328166234 0.11015203148198235 2.0416725676639587 1.4388486737147252e-05 4.84198487918813 -0.6622404738782595 S(ph)HMSGSPGPGGSNTAPSTPVIGGSDKPGMEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHMSGSPGPGGSNTAPSTPVIGGSDKPGMEEK 32 1 A0A499FIX8;H7BXI1;A0A087WXU3;A0FGR8-5;A0FGR8-2;A0FGR8;A0FGR8-6 A0A499FIX8 ESYT2 Extended synaptotagmin-2 1 S(0.194)HMS(0.194)GS(0.194)PGPGGS(0.194)NT(0.194)APS(0.015)T(0.015)PVIGGSDKPGMEEK 43.992 0.0060038 14399000.0 8963.4 11417.0 7701.3 11924.0 15722.0 10738.0 10429.0 8846.9 8035.6 7470.9 True False 10480.726584780301 12550.404307675604 7884.9281993428895 11255.936938129591 12641.386961321334 10174.880376831352 9441.089620578563 8614.678249065377 8153.105448138349 8825.315030388145 1.1875753498534714 1.422091366082784 0.8934443894855619 1.2754147471645039 1.4324006472056052 1.1529197928681592 1.0697736667835795 0.9761326614860224 0.9238316615401058 1.0 13.10743206272486 -7.375309909063778 2.228150752036711 0.9649811180809429 1.2362743987729612 0.4148517404109948 0.14193947277890917 0.32843059385009715 3.183889891623429 0.07563598932273309 0.0450064844893115 4.2139569152258795e-08 7.375309909063778 0.2712932806920183 S(ph)HNNFVAILDLPEGEHQYK ddPTM_PC-9_AZD4547_30min_R2 1 SHNNFVAILDLPEGEHQYK 19 0 Q9Y478 Q9Y478 PRKAB1 5-AMP-activated protein kinase subunit beta-1 1 S(1)HNNFVAILDLPEGEHQYK 116.94 3.6747e-05 5082300.0 14529.0 16543.0 21425.0 29598.0 24068.0 23745.0 18372.0 27072.0 21483.0 22577.0 True False 19148.91977802641 21890.201234003052 21140.8905011537 22774.638384541533 20726.573643920707 22260.221396319706 20007.072408720047 22888.644452672106 22618.547521586257 21786.586101903973 0.8789316365794891 1.004755914103037 0.9703626994275232 1.0453514046678112 0.9513456374934011 1.0217397664875243 0.9183206728736445 1.050584260682853 1.0381868648805688 1.0 14.411152527370097 -4.759691565911337 24.979589606372947 0.9987389469182508 0.8789314856266204 0.44425407495413993 0.040622734140986716 41.532049627137404 593397.4316627757 0.009751922483788604 0.06076741895181878 1.739035445843764e-05 4.759691565911337 -0.11980746129163045 S(ph)HNNFVAILDLPEGEHQYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHNNFVAILDLPEGEHQYK 19 0 Q9Y478 Q9Y478 PRKAB1 5-AMP-activated protein kinase subunit beta-1 1 S(1)HNNFVAILDLPEGEHQYK 178.0 7.2101e-09 5316900.0 24536.0 20371.0 25412.0 33039.0 36302.0 29083.0 29977.0 29970.0 29380.0 23065.0 True False 28689.46019191037 22393.298252751134 26017.918455546685 31187.93194388321 29188.883696087472 27557.836282304543 27137.361545314387 29183.319255839833 29809.626918500766 27246.50191756047 1.0529593956213479 0.8218779174114301 0.9549085799809789 1.1446582037667916 1.071289216663631 1.0114265811327294 0.9959943345176453 1.0710849908050428 1.0940717090471108 1.0 14.733783398791816 -5.576443327592879 9.943778171013394 1.0545702043287348 0.9252061228563816 0.36683743111568046 0.06745229473999326 0.3622651075481082 64.6680933454691 0.017916004094219406 0.031078441828304524 2.651897124548438e-06 5.576443327592879 -0.12936408147235323 S(ph)HNNFVAILDLPEGEHQYK ddPTM_PC-9_Lapatinib_30min_R1 2 SHNNFVAILDLPEGEHQYK 19 0 Q9Y478 Q9Y478 PRKAB1 5-AMP-activated protein kinase subunit beta-1 1 S(1)HNNFVAILDLPEGEHQYK;S(1)HNNFVAILDLPEGEHQYK 104.16 0.00022826 1673900.0 32589.0 30599.0 35376.0 27470.0 29408.0 28492.0 24382.4 25101.0 36421.0 18651.1 True False 32124.274883909344 30528.14989549696 32467.52183530902 29490.235437233656 27678.27925835255 27273.463578095976 25644.80136800055 26267.284095705658 32318.883449867346 21874.91778397141 1.4685437998513544 1.3955778118565596 1.4842351480332976 1.3481301154348695 1.265297521649818 1.2467915924273913 1.172338182993834 1.2007946432124514 1.477440224874748 1.0 14.416989974191347 -6.123567213372483 2.0930921149242483 1.2308683081325638 1.4451048495700638 0.4466831573426935 0.11160543435436872 0.31368325896252036 2.7081759476709064 0.03541292040137021 0.05067526892474201 7.523722806356933e-07 6.123567213372483 0.21423654143750004 S(ph)HSDNDRPNCSWNTQYSSAYYTSR ddPTM_PC-9_AZD4547_30min_R2 2 SHSDNDRPNCSWNTQYSSAYYTSR 24 1 O75494-6;O75494-3 O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 1 S(0.864)HS(0.135)DNDRPNCSWNTQYSSAYYTSR;S(0.398)HS(0.398)DNDRPNCS(0.166)WNT(0.035)QY(0.001)SSAYYTSR 116.6 8.3685e-09 26776000.0 2285.6 2206.7 3278.5 6841.299999999999 7335.120000000001 7585.5 2589.8900000000003 10362.1 6021.700000000001 5534.3 True False 3012.3732565666705 2919.9726206295436 3235.0249478661544 5264.143982031356 6316.765201387557 7111.177485861571 2820.3851927182636 8760.875542369742 6339.994768455797 5340.54584150982 0.5640571855320028 0.5467554641950308 0.605747997278043 0.9856939980021098 1.1827939294687808 1.3315450699045357 0.5281080392188742 1.6404457151692502 1.1871435910497539 1.0 12.382771487734992 -5.842180906172055 2.733112533306458 1.1537151283007312 0.553642249311955 0.489025974904966 0.2620622717202987 0.22495773410964415 3.4046833071096487 0.07729488154563063 0.12977200305888784 1.4381993688486557e-06 5.842180906172055 -0.6000728789887761 S(ph)HSDNDRPNCSWNTQYSSAYYTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SHSDNDRPNCSWNTQYSSAYYTSR 24 1 O75494-6;O75494-3 O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 1 S(0.76)HS(0.075)DNDRPNCS(0.144)WNT(0.017)QY(0.003)S(0.001)S(0.001)AYYTSR;S(0.762)HS(0.103)DNDRPNCS(0.088)WNT(0.029)QY(0.011)S(0.004)S(0.002)AYYTSR 61.525 0.0015754000000000002 19626500.0 0.0 0.0 0.0 2168.76 956.92 924.79 681.26 0.0 0.0 797.51 True False 0.0 0.0 0.0 2047.2514084147872 769.4183953076969 876.2923844002489 616.726120904723 0.0 0.0 942.0922499143142 0.0 0.0 0.0 2.173090170947686 0.8167123711904832 0.9301556025749602 0.6546345338907266 0.0 0.0 1.0 9.879724525597561 -5.607689028279684 24.567844342750345 0.7807085936957633 7.809239006483754e-05 0.2906967032771193 0.569683609424633 29.02294856248228 8402.354822504522 0.16677780005650789 0.28886746464763813 2.467805749533808e-06 5.607689028279684 -0.7806305013056984 S(ph)HSDNDRPNCSWNTQYSSAYYTSR ddPTM_PC-9_Lapatinib_30min_R1 2 SHSDNDRPNCSWNTQYSSAYYTSR 24 1 O75494-6;O75494-3 O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 1 S(0.881)HS(0.108)DNDRPNCS(0.005)WNT(0.002)QY(0.001)S(0.001)S(0.001)AYYTSR;S(0.328)HS(0.328)DNDRPNCS(0.328)WNT(0.015)QY(0.001)SSAYYTSR 49.638000000000005 0.013158000000000001 31445000.0 18726.0 11808.0 20602.0 16139.0 20324.0 20746.0 12363.0 16385.0 22662.0 10679.0 True False 18458.963806072188 11780.659301481357 18908.183086019802 17325.915898125757 19128.582278521397 19858.741941288055 13003.09564737642 17146.306916383306 20109.56691856055 12524.85092112694 1.4737871071132334 0.9405827962079549 1.5096533447855613 1.3833231235431611 1.527250296149655 1.5855471706884987 1.0381836661578763 1.3689829143962813 1.6055733553394795 1.0 13.61250581118304 -10.871156409451219 3.5158582461476593 0.9981255585815807 1.3721227833211889 0.22387439336535941 0.2124244281144841 154909445.49788007 300074757.2094305 3240145.417704829 0.0530838273015536 1.3453757350096777e-11 10.871156409451219 0.37399722473960817 S(ph)HSDTSIASR ddPTM_PC-9_AZD4547_30min_R2 1 SHSDTSIASR 10 0 E9PEM3;H7C357;H0Y6E6;Q92622-3;Q92622-2;Q92622;H7C3H3 E9PEM3 KIAA0226 Run domain Beclin-1 interacting and cysteine-rich containing protein 1 S(0.819)HS(0.18)DTSIASR 71.888 0.030251999999999998 0.0 6415.2 5762.0 9526.1 8663.7 8162.3 11056.0 10300.0 10583.0 8766.6 7930.1 True False 8455.10015555062 7624.453817948709 9399.777689756833 6666.417817830685 7029.105536553679 10364.666572234602 11216.680046256073 8947.64052314675 9229.984578631389 7652.469612734586 1.104885165630761 0.9963389864705564 1.2283325730708587 0.8711459378730497 0.9185407969286727 1.354421134190015 1.4657595016895242 1.1692487492216699 1.2061445579962367 1.0 12.901709695614072 -6.763785735752282 24.999993441564968 1.2638581377133788 1.0251971003551168 0.3446755644769197 0.14643194875920904 67.7336554616209 721682.8030993827 0.051284787630369214 0.04738272722260567 1.722718288520018e-07 6.763785735752282 -0.23866103735826205 S(ph)HSLSGAR ddPTM_PC-9_AZD4547_30min_R2 1 SHSLSGAR 8 0 A0A0J9YYJ3;Q9Y519 A0A0J9YYJ3 TMEM184B Transmembrane protein 184B 1 S(0.748)HS(0.248)LS(0.004)GAR 101.46 0.0045792 10974000.0 18580.0 16250.0 19352.0 28695.0 22630.0 17776.0 24821.0 23384.0 22787.0 23117.0 True False 24488.05351199192 21502.494713930326 19095.379835627817 22079.811083330627 19488.215122233894 16664.46390991699 27030.02091535163 19770.540110863058 23991.474299417496 22307.680866267172 1.0977408928698555 0.9639054298309235 0.8560002247702551 0.9897851424223519 0.8736100914776503 0.7470280756578493 1.2116912142232321 0.8862660457349163 1.0754804339924233 1.0 14.445252916589757 -7.260332453380855 24.99999855676801 1.0338815838823896 0.921250482766162 0.21281773442921692 0.11438138836675747 180.46647678564753 4075921.575868003 0.04519044623104175 0.03299951011621067 5.4912036008296126e-08 7.260332453380855 -0.11263110111622765 S(ph)HSLSQHTATSSK ddPTM_PC-9_Lapatinib_30min_R1 1 SHSLSQHTATSSK 13 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 S(0.353)HS(0.353)LS(0.294)QHTATSSK 62.055 0.028886000000000002 1531500.0 5780.0 4593.2 15416.0 6215.4 9254.5 16528.0 9333.8 10655.0 18485.0 7018.2 True False 5697.576140077818 4582.564727605366 14148.555987480886 6672.501249966588 8710.168505047051 15821.135968649813 9817.058493365847 11150.07019798987 16403.02464432053 8231.286518836323 0.6921853743080855 0.5567252114379339 1.718875409707048 0.8106267756197479 1.058178267165754 1.9220732910274743 1.1926517769610707 1.354596292143914 1.9927656031392118 1.0 13.006902220690579 -4.753841118093802 0.6092178546930818 1.4633733626557461 1.0580781015204286e-14 0.3082717926241104 0.400387857182057 4.545326637284098 1.2481629245737909 0.1989490664954674 4.730316774463751 1.7626207640823803e-05 4.753841118093802 -1.4633733626557355 S(ph)HSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTR ddPTM_PC-9_AZD4547_30min_R2 1 SHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTR 34 1 Q8WXE0-2;Q8WXE0 Q8WXE0-2 CASKIN2 Caskin-2 1 S(0.456)HS(0.4)LS(0.106)RPGPT(0.037)EGDAEGEAEGPVGSTLGSYATLTR 70.833 4.4659e-06 9125500.0 4560.2 2480.5 10160.0 12848.0 14745.0 8863.5 6275.8 9580.7 7622.0 8659.0 True False 6010.248741947555 3282.2731161787196 10025.271761573937 9886.092099621248 12697.911267226635 8309.263943831531 6834.334042164445 8100.222957584055 8024.883359378597 8355.851045594478 0.7192862473435768 0.39281134839152726 1.1997906265765281 1.1831340752338533 1.5196430857777743 0.9944246131831767 0.8179099896434566 0.969407294766797 0.9603909063948214 1.0 13.02857105929574 -5.264713772840771 24.99618115013467 1.0863793228650291 0.5560487820939809 0.5360495378679246 0.19513648648478818 212.14758040818447 1619513.2712997713 0.05572456363649307 0.1242467128392921 5.436084853642113e-06 5.264713772840771 -0.5303305407710482 S(ph)HSPSASQSGSQLR ddPTM_PC-9_AZD4547_30min_R2 1 SHSPSASQSGSQLR 14 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.5)HS(0.5)PS(0.001)ASQSGSQLR 75.589 0.027818 0.0 1304.6 1171.4 2394.7 3512.7 2511.9 3852.5 2470.6 3045.2 2157.2 2494.2 True False 1719.435662634266 1550.032142024491 2362.9447133308163 2702.9012856739996 2163.166043550126 3611.6025659853294 2690.4786138136155 2574.634311734526 2271.225187988914 2406.878817175395 0.7143839774418383 0.6440009073009912 0.9817464412703014 1.1229901839619842 0.8987432304916458 1.5005336123335633 1.1178288639272003 1.06969835513198 0.9436391943713736 1.0 11.232947790719932 -5.39738116960736 3.094199650010475 1.1052117162750226 0.674768184585468 0.5211867858210975 0.15572593425977857 0.1975599383877769 3.539330582666816 0.04344567679360573 0.10501172097812482 4.0051504109969354e-06 5.39738116960736 -0.4304435316895546 S(ph)HSPSASQSGSQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SHSPSASQSGSQLR 14 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.541)HS(0.451)PS(0.007)AS(0.001)QSGSQLR;S(0.531)HS(0.448)PS(0.021)ASQSGSQLR 67.275 0.019662 23617100.0 10861.099999999999 12046.4 19722.2 17376.9 21659.0 24678.0 19104.9 18769.7 16283.8 15357.8 True False 12699.66971349681 13242.286980115914 20192.45204486002 16403.32862966992 17415.07443043244 23383.842236863868 17295.145564502014 18277.015263141024 16521.919769077016 18142.047567722093 0.7000130313896744 0.7299224043308254 1.113019463182643 0.9041608213426988 0.9599288264141107 1.2889307091481699 0.9533182789837423 1.0074394962815036 0.9106976325248111 1.0 14.14704967163929 -5.247298774777026 23.103355915613257 1.0187951277133935 0.7149674894271716 0.5588160292554154 0.10740554411824937 211.91072501092955 346221.2187990708 0.027700786373838257 0.0723279435104269 5.658498762219748e-06 5.247298774777026 -0.30382763828622195 S(ph)HSPSASQSGSQLR ddPTM_PC-9_Lapatinib_30min_R1 2 SHSPSASQSGSQLR 14 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.504)HS(0.427)PS(0.068)AS(0.001)QSGSQLR;S(0.562)HS(0.426)PS(0.012)ASQSGSQLR 89.506 0.003002 20314400.0 34156.0 22443.0 33782.0 20744.6 27851.0 32105.0 24891.0 29407.0 37381.0 21997.7 True False 33668.92917655672 22391.034612393814 31004.57436229109 22270.227085956954 26212.858937172765 30731.943990410327 26179.734187401624 30773.356575531514 33170.758140619175 25799.97313490723 1.304998613777734 0.8678704623183835 1.2017289398004085 0.8631879951776171 1.0160033423332098 1.1911618601195426 1.0147194359664111 1.1927670007491333 1.285689638790333 1.0 14.655081942943859 -7.770401392115054 24.843455327232373 1.179421284911284 1.0584217129284266 0.0712057249524034 0.1485783797677713 389.3616477383953 1079322.3014895462 0.07499874313946565 0.036857283417152706 1.696674793708844e-08 7.770401392115054 -0.12099957198285738 S(ph)HSPSIDGTPK ddPTM_PC-9_Lapatinib_30min_R1 1 SHSPSIDGTPK 11 0 A0A0C4DH56;Q9BWT3-2;Q9BWT3 A0A0C4DH56 PAPOLG Poly(A) polymerase gamma 1 S(0.943)HS(0.057)PSIDGTPK 84.89200000000001 0.0066652000000000005 7902400.0 107530.0 100030.0 105350.0 94069.0 108670.0 113000.0 111390.0 115300.0 116640.0 82199.0 True False 105996.6024814133 99798.38668082468 96688.5296627603 100987.14806498474 102278.24425344015 108167.25341586558 117157.22916454416 120657.25892334452 103502.77492634811 96406.98762671713 1.0994701223507435 1.0351779382137618 1.002920348856177 1.0475085940450888 1.0609007372936101 1.1219856161742505 1.215235866700564 1.2515405977679044 1.0736024169441483 1.0 16.55685009705308 -6.81410673627124 3.1519015008195317 1.1572505864235223 1.0439986630972713 0.23907001263742578 0.07005422015374548 0.2776765305884418 5.6190438072105815 0.025460988598790563 0.022976917184836573 1.5342398673290859e-07 6.81410673627124 -0.113251923326251 S(ph)HSQASLAGPGPVDPSNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHSQASLAGPGPVDPSNR 18 0 Q9P2M7-2;Q9P2M7;A6PVU7;A2A3M4 Q9P2M7-2 CGN Cingulin 1 S(0.566)HS(0.434)QASLAGPGPVDPSNR 120.33 4.5198e-05 51041000.0 24094.0 17865.0 30181.0 32782.0 37274.0 31800.0 29525.0 28434.0 30024.0 28266.0 True False 28172.63832180831 19638.519134328166 30900.62950207988 30945.330820678 29970.427273647845 30132.352019299415 26728.17825751101 27687.63762831329 30463.04420017248 33390.4020464671 0.8437346241774032 0.5881486274708105 0.9254344844089516 0.9267732319489156 0.8975761127985248 0.902425552629355 0.8004748855768572 0.8292094713259915 0.9123293621256546 1.0 15.027145844227874 -5.28206435700529 24.996846616088494 0.8906831693800875 0.7159416040217816 0.4711892038861263 0.07726120392624786 596.2912396610786 722686.0885453426 0.01949262503810825 0.04064923176032469 5.223187821592861e-06 5.28206435700529 -0.17474156535830587 S(ph)HSQASLAGPGPVDPSNR ddPTM_PC-9_Lapatinib_30min_R1 4 SHSQASLAGPGPVDPSNR 18 0 Q9P2M7-2;Q9P2M7;A6PVU7;A2A3M4 Q9P2M7-2 CGN Cingulin 1 S(0.548)HS(0.44)QAS(0.012)LAGPGPVDPSNR;S(0.532)HS(0.459)QAS(0.009)LAGPGPVDPSNR;S(0.544)HS(0.451)QAS(0.005)LAGPGPVDPSNR;S(0.555)HS(0.441)QAS(0.003)LAGPGPVDPSNR 93.712 0.00057149 144065000.0 94096.0 68594.5 121603.0 91039.0 115170.0 110336.0 102920.0 86139.0 114755.0 73509.0 True False 92754.17378490706 68435.67364968368 111605.27074115467 97734.31175720114 108395.92703293198 105617.18648577845 108248.69400857238 90141.33240588005 101830.08347627829 86214.93270541445 1.0758481260066208 0.793779818671549 1.2945004680627172 1.133612341740693 1.2572755511311153 1.225045165280811 1.2555678072433751 1.045541991129096 1.181118865153196 1.0 16.39565014995724 -5.2654636249680085 24.999393617782804 1.1819653365086285 0.9348139717268625 0.4326786577515733 0.10929397174665968 263.8606066371945 1639164.7561313135 0.02684468624412845 0.05937272388517113 5.426707016819812e-06 5.2654636249680085 -0.24715136478176591 S(ph)HSSEKPYECSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHSSEKPYECSK 12 1 A0A0D9SFC3;Q5HYK9 A0A0D9SFC3 ZNF667 Zinc finger protein 667 1 S(0.954)HS(0.033)S(0.006)EKPY(0.006)ECSK 53.211000000000006 0.043151 24218000.0 47057.0 74224.0 62373.0 88622.0 39706.0 95085.0 84498.0 48460.0 88394.0 77501.0 True False 55022.82068188482 81592.46819067311 63860.20887091975 83656.79665640046 31925.894331905933 90098.57521242413 76493.73772745676 47187.97634761423 89686.59502498145 91551.31780242157 0.601005228571701 0.8912211221990183 0.697534567538804 0.913769442805199 0.34872129750011616 0.9841319314143283 0.8355285272085232 0.5154265113851381 0.9796319395263713 1.0 16.482293032074907 -8.405453133497254 9.384902220513245 0.9995629817878213 0.7345362528227631 0.2461758172291194 0.18580976491768345 0.4772423528880621 33.831690947484304 0.16977936978712113 0.043858580887193244 3.9313966793600525e-09 8.405453133497254 -0.2650267289650582 S(ph)HSSPASLQLGTGAGAAGSPAQQHAHLR ddPTM_PC-9_AZD4547_30min_R2 1 SHSSPASLQLGTGAGAAGSPAQQHAHLR 28 0 Q9GZV5;C9JR84;C9J038 Q9GZV5 WWTR1 WW domain-containing transcription regulator protein 1 1 S(0.307)HS(0.307)S(0.307)PAS(0.079)LQLGTGAGAAGSPAQQHAHLR 129.74 8.7447e-11 12689000.0 17863.0 10413.0 32136.0 74607.0 44019.0 34501.0 18817.0 49171.0 24147.0 40477.0 True False 23543.06242651839 13778.798612686549 31709.855642710623 57407.50881665967 37907.72167324852 32343.64701597919 20491.676546640803 41572.75178717275 25423.36112292247 39059.91255023993 0.6027423229951336 0.35276061089394095 0.8118260787687257 1.4697295787034994 0.9705019596367648 0.8280522127226451 0.5246216698586779 1.0643329457970683 0.6508811582776137 1.0 15.253401098782438 -5.4004631902141185 5.528122780057207 0.9284799880109419 0.4849380288796781 0.3436667635254903 0.24543798203376824 0.25305737433452774 10.285486296516215 0.0678800153630817 0.14428084041991185 3.976828017115411e-06 5.4004631902141185 -0.4435419591312638 S(ph)HSSPASLQLGTGAGAAGSPAQQHAHLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHSSPASLQLGTGAGAAGSPAQQHAHLR 28 0 Q9GZV5;C9JR84;C9J038 Q9GZV5 WWTR1 WW domain-containing transcription regulator protein 1 1 S(0.324)HS(0.324)S(0.324)PAS(0.027)LQLGTGAGAAGSPAQQHAHLR 84.646 4.249e-07 7810500.0 13152.0 9852.1 13389.0 16069.0 25321.0 21763.0 14714.0 15829.0 16194.0 11726.0 True False 15378.37383615933 10830.151377739408 13708.244538065257 15168.706026400905 20359.53181831939 20621.709968428095 13320.183399865098 15413.505522211828 16430.806613961922 13851.830977035072 1.1102051318453936 0.781857026388403 0.9896341184636265 1.0950686628756212 1.4698079879889832 1.4887353161193488 0.9616189673371418 1.112741380382554 1.1861830137259493 1.0 13.75778906823527 -5.86579184414724 3.5702691669589046 1.21534094006212 0.9400076836089633 0.26284143007869987 0.17892689770679948 0.3017963589543781 7.426029678797116 0.054961980875090646 0.08684589809855958 1.362097374627827e-06 5.86579184414724 -0.27533325645315676 S(ph)HSSPASLQLGTGAGAAGSPAQQHAHLR ddPTM_PC-9_Lapatinib_30min_R1 2 SHSSPASLQLGTGAGAAGSPAQQHAHLR 28 0 Q9GZV5;C9JR84;C9J038 Q9GZV5 WWTR1 WW domain-containing transcription regulator protein 1 1 S(0.326)HS(0.326)S(0.326)PAS(0.022)LQLGTGAGAAGSPAQQHAHLR;S(0.313)HS(0.313)S(0.313)PAS(0.06)LQLGTGAGAAGSPAQQHAHLR 102.46 4.9255e-10 10891300.0 33662.4 29463.4 62648.0 29029.1 38953.0 48614.0 27760.3 38113.2 66797.0 29540.0 True False 33182.3680030719 29395.17930752592 57497.32326827334 31163.996852238815 36661.86112454458 46534.892544769005 29197.592501808922 39884.0784110772 59273.61845640672 34645.94964042417 0.9577560536645069 0.8484449008500617 1.659568401646196 0.8994989941299607 1.0581860651834547 1.3431553479623217 0.8427418732878887 1.151190220646782 1.7108383251601653 1.0 15.080399080390144 -8.024309589750317 24.804696304215053 1.3806176072519858 1.0939585838077956 0.11909334000494487 0.2858253168068619 1340.1113613892207 1367395.7504002322 0.1824248608894101 0.06977494817208123 9.455628701889288e-09 8.024309589750317 -0.28665902344419014 S(ph)HSSPSQIPK ddPTM_PC-9_AZD4547_30min_R2 3 SHSSPSQIPK 10 0 Q9H792;H0YN99 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 S(0.332)HS(0.332)S(0.332)PS(0.004)QIPK;S(0.333)HS(0.333)S(0.333)PS(0.002)QIPK;S(0.332)HS(0.332)S(0.332)PS(0.005)QIPK 96.334 0.0031571999999999998 30798800.0 162278.0 171170.0 289568.0 350818.0 337707.0 284028.0 263330.0 350129.0 256946.0 301651.0 True False 213879.02840791355 226497.35508821273 285728.1391196299 269942.3301840698 290822.2122971389 266267.6842600076 286765.85986219504 296024.60821400833 270527.64099434455 291090.2903054186 0.7347515033342636 0.7781000006924536 0.9815790791916742 0.9273491393369395 0.9990790554779465 0.9147254069540878 0.985144023736806 1.0169511593925462 0.9293598928033661 1.0 18.151107191733807 -5.2061739076477265 4.2525238267085825 0.9685127287562972 0.7458966067297946 0.8653919542485907 0.033678271142630785 0.06745001908571814 2.5517287519906526 0.008426558019559762 0.023981080579357994 6.220511428982742e-06 5.2061739076477265 -0.2226161220265026 S(ph)HSSPSQIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SHSSPSQIPK 10 0 Q9H792;H0YN99 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 S(0.408)HS(0.294)S(0.294)PS(0.004)QIPK;S(0.33)HS(0.33)S(0.33)PS(0.009)QIPK 95.40100000000001 0.0033613 14184700.0 198858.0 227640.0 258360.0 284970.0 357390.0 290810.0 313600.0 287980.0 266410.0 231060.0 True False 232520.7317754695 250238.5947796505 264520.2822357561 269004.05478520493 287361.99504558137 275559.4116582537 283893.5377326154 280420.83014003193 270305.7422517965 272949.3489300464 0.8518823462556113 0.916794986910863 0.9691185682349783 0.985545691314865 1.052803372391369 1.0095624435025716 1.0400960428939285 1.027373141717588 0.9903146620843287 1.0 18.058273730244302 -5.029021560024565 1.0280456233360094 1.021640203954917 0.8065162707248337 0.8885395806614675 0.019151116855321774 0.3828500655696874 0.4322842811449176 0.006390076935890119 0.08280080728624481 9.353592382162453e-06 5.029021560024565 -0.2151239332300834 S(ph)HSSPSQIPK ddPTM_PC-9_Lapatinib_30min_R1 2 SHSSPSQIPK 10 0 Q9H792;H0YN99 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 S(0.331)HS(0.331)S(0.331)PS(0.006)QIPK;S(0.584)HS(0.194)S(0.194)PS(0.029)QIPK 88.18700000000001 0.0057515 16528800.0 180582.0 160565.0 189590.0 161973.0 169800.0 158377.0 141530.0 145472.0 188627.0 110423.0 True False 178006.8675653174 160193.22160758384 174002.64203856362 173885.0347460884 159812.6978396442 151603.58490481903 148857.73088839152 152231.1601916456 167381.840929632 129509.46842060148 1.3744699112439664 1.236922856384 1.3435515114112264 1.3426434133863525 1.2339846637361558 1.1705984647582954 1.1493965090255305 1.17544425166855 1.292429371928501 1.0 16.982698051453603 -6.506171567766497 3.018789535216369 1.168259115325607 1.3191139701762258 0.5237617183370663 0.07441548182403791 0.2272756951243222 4.214337336070715 0.024447575649576603 0.02632767597542773 3.11765771203371e-07 6.506171567766497 0.15085485485061878 S(ph)HSSSEAYEPR ddPTM_PC-9_AZD4547_30min_R2 1 SHSSSEAYEPR 11 0 Q8IVF2-3;Q8IVF2 Q8IVF2-3 AHNAK2 Protein AHNAK2 1 S(0.926)HS(0.069)S(0.002)S(0.003)EAYEPR 114.71 0.0014312 9217200.0 5788.1 5352.7 9831.8 15729.0 11061.0 10199.0 5825.7 11239.0 10290.0 12651.0 True False 7628.595400040926 7082.855597246454 9701.423908016004 12102.922060627545 9525.371076757807 9561.254917711709 6344.1760141236855 9502.270796527111 10833.908392548647 12208.092340664716 0.6248802177413377 0.5801770988947812 0.7946715700782268 0.9913851994969883 0.7802505756799643 0.7831899244293486 0.5196697270212696 0.7783583652030046 0.887436635489829 1.0 13.575550159262056 -14.522878745278396 0.17358771240377863 1.9998778707448492 0.6920963264505471 0.281518512353224 0.13028697490620172 209.37597971253834 1.9842663661452205 72.01897255402253 0.4951508157364769 3.000000000013413e-15 14.522878745278396 -1.3077815442943022 S(ph)HSSSEAYEPR ddPTM_PC-9_Lapatinib_30min_R1 1 SHSSSEAYEPR 11 0 Q8IVF2-3;Q8IVF2 Q8IVF2-3 AHNAK2 Protein AHNAK2 1 S(0.85)HS(0.134)S(0.008)S(0.008)EAYEPR 116.74 0.0012312999999999998 1974100.0 6499.9 6434.4 11648.0 6619.5 10341.0 9669.3 8873.7 7826.8 13816.0 5726.1 True False 6407.210234064326 6419.501542128358 10690.346402580262 7106.320112004674 9732.762711188232 9255.766579239204 9333.136766652435 8190.461701138166 12259.896591070188 6715.848755451356 0.9540432590688551 0.9558734533617291 1.591808688946836 1.0581417734037513 1.4492230342870664 1.3781975914401225 1.3897181289374014 1.2195720897511046 1.8255170772150944 1.0 12.713354025029755 -5.238776326970599 23.911146640678147 1.3654066957152595 0.9549580840850401 0.3398900450535821 0.22802247223148905 481.2059622258039 507702.9547546417 0.053715260145739706 0.1418467283125167 5.770635897298459e-06 5.238776326970599 -0.4104486116302194 S(ph)HSTEPNLSSFLNDPNPMK ddPTM_PC-9_Lapatinib_30min_R1 1 SHSTEPNLSSFLNDPNPMK 19 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 S(0.497)HS(0.232)T(0.256)EPNLS(0.007)S(0.007)FLNDPNPMK 60.464 0.011144 2573100.0 10414.0 7931.8 11024.0 8080.5 15952.0 16315.0 15873.0 13273.0 16613.0 16129.0 True False 10265.494450306292 7913.434404428337 10117.649273870606 8674.7669257578 15013.734722838673 15617.245482122555 16694.82627281452 13889.712035468765 14741.868997354451 18916.87615945841 0.5426633004188464 0.41832670139206 0.5348477829312106 0.4585729087950089 0.7936688170013646 0.8255721161611536 0.8825361086094086 0.7342497735031124 0.7792972197464823 1.0 14.207386248282324 -6.297312095733901 5.378369423465008 0.8267579528171269 0.48622563879877184 0.8388729567564841 0.07454582586714982 0.07336540050787271 5.854525022398488 0.02232565158272492 0.026002407694315926 5.042987646156646e-07 6.297312095733901 -0.3405323140183551 S(ph)HSVPENMVEPPLSGR ddPTM_PC-9_AZD4547_30min_R2 1 SHSVPENMVEPPLSGR 16 0 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 S(0.894)HS(0.106)VPENMVEPPLSGR 90.22 0.0020201 4247200.0 24849.0 21786.0 31184.0 45443.0 31345.0 28098.0 30625.0 42809.0 37830.0 34761.0 True False 32750.46510869148 28827.898451549918 30770.479784736344 34966.818437351234 26993.287804084048 26341.02761818449 33350.5656715138 36193.85270295659 39829.61656852435 33544.02797042495 0.9763426484609082 0.8594047941102022 0.9173161855179115 1.0424156117500478 0.8047121779138585 0.7852672804055855 0.9942325859291044 1.078995424606369 1.1873832386391183 1.0 15.03376831782685 -7.6004801440958945 3.514843884762054 1.099849761067352 0.8983616270016775 0.5134794850277606 0.08313819334130208 0.19181960789617983 4.717867525350643 0.04422555503487352 0.02403594489833219 2.5091108931642384e-08 7.6004801440958945 -0.20148813406567456 S(ph)HSVPENMVEPPLSGR ddPTM_PC-9_Lapatinib_30min_R1 2 SHSVPENMVEPPLSGR 16 0 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 S(0.558)HS(0.442)VPENMVEPPLSGR;S(0.878)HS(0.122)VPENMVEPPLSGR 114.53 0.00010861 20580500.0 94599.0 77208.0 84112.0 78297.0 115743.0 107462.0 113250.0 90293.0 123342.0 124445.0 True False 93250.00091266792 77029.22961964541 77196.6360417094 84055.22257113528 108935.22429949323 102866.1007661573 119113.53086349432 94488.3424108025 109449.92511115936 145955.15243746084 0.6388948889805303 0.5277595777418755 0.5289065493921962 0.5758976039379728 0.7463609367690532 0.7047788245107247 0.8160967864052099 0.6473792862591067 0.7498873680259879 1.0 17.15516561549122 -14.522878744634195 0.06382370268405745 2.290231797545359 0.15100721118244045 0.7510674029745661 0.06851424561721053 185.8217098556412 0.858534834012107 36.135998477339484 5.3606554139134746 3.000000004463397e-15 14.522878744634195 -2.1392245863629187 S(ph)HTFNCRMLMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHTFNCRMLMK 11 1 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 S(0.983)HT(0.017)FNCRMLMK 81.525 0.028168000000000002 0.0 24396.0 23130.0 20542.0 19080.0 24505.0 20693.0 28478.0 20337.0 20599.0 18699.0 True False 28525.760957036397 25426.19353915535 21031.799185968826 18011.00945819462 19703.42116061437 19607.822652055424 25780.357677134572 19803.17529883264 20900.22140552066 22088.98067879745 1.291402322806929 1.1510804372951982 0.9521398697295534 0.815384363819144 0.8920022814600537 0.8876743991576028 1.1671139584037196 0.8965182951081629 0.9461831539190108 1.0 14.431039224970839 -5.084047699651458 2.6665891213921777 0.939532561331533 1.28435263081505 0.6263573200674988 0.08856493767008615 0.2010838951838028 2.5939294842618765 0.024903443374461244 0.11203854482541406 8.24047602828902e-06 5.084047699651458 0.34482006948351696 S(ph)IDDLEEK ddPTM_PC-9_AZD4547_30min_R2 2 SIDDLEEK 8 0 P09493-3;P09493-9;P09493-8;Q6ZN40;H7BYY1;P09493-2;P09493-7 P09493-3 TPM1 Tropomyosin alpha-1 chain 1 S(1)IDDLEEK;S(1)IDDLEEK 100.88 0.0047576 5121700.0 25304.8 25733.2 24601.7 35598.0 29123.0 29962.0 25434.0 32080.0 30910.0 29397.0 True False 33351.20002746251 34050.95365984688 24275.465383534785 27391.431083617477 25079.774149572142 28088.471403517822 27697.57672781329 27122.773125063588 32543.83949598434 28367.819977750398 1.1756701802824716 1.2003373430370718 0.8557395458154574 0.9655811093380201 0.8840924036194127 0.9901526245424683 0.9763731139557853 0.9561105910266163 1.1472097440518623 1.0 14.791967665581753 -5.244279409106212 24.712582775413676 0.9677888308265131 1.1880038214791102 0.5808930703604127 0.0733545418558159 476.2903119058543 685916.5942943108 0.018526622828447727 0.04874386257185876 5.697975675204293e-06 5.244279409106212 0.2202149906525971 S(ph)IDDLEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SIDDLEEK 8 0 P09493-3;P09493-9;P09493-8;Q6ZN40;H7BYY1;P09493-2;P09493-7 P09493-3 TPM1 Tropomyosin alpha-1 chain 1 S(1)IDDLEEK 82.417 0.016499 2527100.0 8143.4 10121.0 16446.0 15415.0 18678.0 16083.0 13778.0 14487.0 14931.0 10489.0 True False 9521.916780518546 11125.74599264121 16838.13501180231 14551.347526104302 15018.179981144895 15239.579167496619 12472.848095918254 14106.731600245306 15149.337628323181 12390.57266912168 0.7684807663690914 0.8979202406332258 1.3589472788262902 1.1743886190480484 1.2120650418823196 1.2299333997269468 1.006640163372078 1.1385052149688315 1.2226503191476024 1.0 13.596955247238554 -5.0754512965396605 5.576615103810935 1.1704637637168123 0.7965084582208817 0.6468588150181342 0.10084918072836098 0.11318652449081756 6.1413036838736295 0.025638384722458798 0.07320393175127063 8.405212611149447e-06 5.0754512965396605 -0.3739553054959306 S(ph)IDDLEEK ddPTM_PC-9_Lapatinib_30min_R1 2 SIDDLEEK 8 0 P09493-3;P09493-9;P09493-8;Q6ZN40;H7BYY1;P09493-2;P09493-7 P09493-3 TPM1 Tropomyosin alpha-1 chain 1 S(1)IDDLEEK;S(1)IDDLEEK 133.81 0.004082 5225200.0 29874.0 24422.0 27501.0 25122.0 25443.0 24826.0 23973.0 22521.0 23053.0 20650.7 True False 29447.991281779367 24365.45235948322 25239.973936929942 26969.5556845353 23946.492762862606 23764.249852232573 25214.20463921013 23567.407876952595 20456.528381148015 24220.145979671892 1.21584697740861 1.0059994014872282 1.0421065982886313 1.1135174704219786 0.9887014216578643 0.9811769868017329 1.0410426370003119 0.973049786600496 0.8446079721533181 1.0 14.563919940019925 -1.5228787452803498 0.28816068571024367 0.9483452518175793 2.6152360109682466 0.505990247002891 0.06444827915861662 48.118090119332706 0.6820904806284314 0.07026324751319762 40.779838466628554 0.029999999999999152 1.5228787452803498 1.6668907591506672 S(ph)IDPDSIQSALLASGLGSK ddPTM_PC-9_Lapatinib_30min_R1 1 SIDPDSIQSALLASGLGSK 19 0 A3KN83-3;A3KN83-2;A3KN83 A3KN83-3 SBNO1 Protein strawberry notch homolog 1 1 S(0.998)IDPDS(0.002)IQSALLASGLGSK 86.291 0.0071735 0.0 2742.5 2823.1 2503.1 2477.5 2182.6 2081.4 2163.7 2600.4 4122.1 2261.3 True False 2703.391447087095 2816.563285400747 2297.3047802454203 2659.703614697724 2054.223759156702 1992.3833739803795 2275.725798934591 2721.224077226925 3657.8256903626534 2652.162692007149 1.0193158418351689 1.0619873712457588 0.8662005491476191 1.002843310749111 0.774546661616023 0.7512296964227898 0.8580641775080277 1.0260396488601198 1.3791860135074978 1.0 11.372953562281774 -8.018247782172459 6.540060530164796 1.1958596817025857 0.9045004838242933 0.4405880899167316 0.1279515046665839 0.1494448709408033 26.77069620439405 0.08361612257749529 0.03411571938838337 9.588534116443313e-09 8.018247782172459 -0.29135919787829245 S(ph)IDPVLMAPT(ph)CVFLASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SIDPVLMAPTCVFLASK 17 0 E5RIH8;Q5JV82;E5RI39;G5E954;H0YBQ5;J3KP90;E5RFK5;P24863 E5RIH8 CCNC Cyclin-C 2 S(1)IDPVLMAPT(0.997)CVFLAS(0.003)K 53.995 0.042341000000000004 7010600.0 22206.0 25575.0 23894.0 23090.0 31651.0 25619.0 21784.0 30502.0 20033.0 18618.0 True False 25965.03721150805 28113.91698071326 24463.723578499605 21796.34215879002 25449.2137586046 24275.49454032803 19720.461817497708 29701.354819540433 20325.94472628746 21993.296019993093 1.1805887206676267 1.278294847446067 1.112326390562868 0.9910448228849359 1.1571350531302762 1.1037679171989634 0.8966578633584863 1.350473107466034 0.9241882029783112 1.0 14.424776209088673 -5.411049213257459 5.184114751329743 1.0725754638633382 1.2273061044809348 0.21839607562474983 0.12458270223220716 0.3308383150740628 12.82487343242389 0.03105161555113369 0.06626705937120371 3.881063841708797e-06 5.411049213257459 0.15473064061759656 S(ph)IDQDYER ddPTM_PC-9_AZD4547_30min_R2 2 SIDQDYER 8 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(1)IDQDYER;S(1)IDQDYER 110.84 0.0037555999999999996 207426000.0 212785.0 189068.0 265710.0 273270.0 227620.0 243210.0 266010.0 329670.0 252310.0 230550.0 True False 280446.203797051 250180.5335737462 262186.5117881702 210271.82347941282 196018.8920071977 228002.0402526389 289684.37467034766 278727.0765629591 265646.5914989262 222478.51467395804 1.260554099833166 1.1245154793503787 1.1784801430034904 0.9451331684210761 0.8810688631864659 1.0248272314599707 1.3020779786078658 1.2528269391380704 1.1940325648444343 1.0 17.763306492448415 -9.328018384449917 13.359743355735478 0.9999862750628088 1.123514094314894 0.07740457322789973 0.1325596098354378 0.0 0.0 0.14484398940315812 0.03512982750265095 4.69874217581447e-10 9.328018384449917 0.12352781925208522 S(ph)IDQDYER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SIDQDYER 8 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(1)IDQDYER 93.44200000000001 0.0072217 61144000.0 74568.0 113380.0 98600.0 113870.0 114610.0 113150.0 114710.0 87676.0 91193.0 78386.0 True False 87190.8896148667 124635.61709768417 100950.99794258214 107490.23307152087 92152.99323476882 107216.21481080899 103843.8383715184 85374.59790040064 92526.52510479375 92596.76129676557 0.9416192142555239 1.3460040648531595 1.0902216938132627 1.1608422537265948 0.9952075206974624 1.1578829897429046 1.1214629639011542 0.9220041468489546 0.9992414832766481 1.0 16.498674113609397 -7.749502997019069 24.655117693028956 0.9704671204448668 1.1226877485421176 0.2837438428399076 0.10329861539309772 210.74087962654372 435296.8353006451 0.04683623242330887 0.026759342307611067 1.7803156230465096e-08 7.749502997019069 0.1522206280972508 S(ph)IDQDYER ddPTM_PC-9_Lapatinib_30min_R1 2 SIDQDYER 8 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(1)IDQDYER;S(1)IDQDYER 110.39 0.0037628 245601000.0 276450.0 256430.0 268110.0 252980.0 274240.0 233010.0 266810.0 255140.0 275040.0 216190.0 True False 272507.7723052785 255836.2520900119 246067.03073452853 271584.99311654124 258109.74237658488 223044.70547283947 280624.11628864356 266994.73583436233 244062.09890040132 253558.15344493272 1.0747348038423905 1.008984521357835 0.9704559975349754 1.0710954841194786 1.0179508679559803 0.879658975436102 1.1067445967561402 1.0529921132760882 0.9625488101427047 1.0 17.951957141053718 -4.761023424971141 22.73855887604326 1.0096934915053155 1.0747350326425857 0.10020553303299196 0.05991470660823811 8.318103105716041 452865.369130726 0.014886903420180805 0.08476531415691003 1.733710482374606e-05 4.761023424971141 0.06504154113727023 S(ph)IDST(ph)KSRS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 SIDSTKSRSR 10 2 Q8N2Y8 Q8N2Y8 RUSC2 Iporin 3 S(0.981)IDS(0.099)T(0.919)KSRS(1)R 142.97 0.0021879 26728000.0 0.0 0.0 0.0 0.0 0.0 0.0 2712.7 2963.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 2954.1250448037686 2505.136432966439 0.0 0.0 0.0 S(ph)IEALLEAGQAR ddPTM_PC-9_AZD4547_30min_R2 1 SIEALLEAGQAR 12 0 Q9P2E9;A0A087WVV2;Q9P2E9-3;F8W7S5 Q9P2E9 RRBP1 Ribosome-binding protein 1 1 S(1)IEALLEAGQAR 86.699 0.032080000000000004 0.0 848.55 2443.7 3109.4 4088.7 3641.7 5672.2 3380.7 3254.8 2399.1 2384.5 True False 1118.371249063549 3233.578235841941 3068.167324354133 3146.113384785291 3136.1128153176846 5317.516437321735 3681.5757507163016 2751.8454478633707 2525.911528140277 2301.019380785313 0.4860329549601016 1.4052807476738227 1.3333948205629633 1.3672693985356859 1.3629232511059353 2.310939439157146 1.5999759851913198 1.1959244980040957 1.097735877078189 1.0 11.168057419656122 -4.759562781856204 5.3781803788632905 1.446618702158268 0.43457967554239796 0.3895986991495993 0.3436227642451552 0.17192710735831945 15.0132827772074 0.09068381697403301 0.6516627825069676 1.7395512093532857e-05 4.759562781856204 -1.01203902661587 S(ph)IEDDEEGHLICQSGDVLR ddPTM_PC-9_AZD4547_30min_R2 1 SIEDDEEGHLICQSGDVLR 19 0 A0A087WX74;B7ZL31;Q9HAZ1 A0A087WX74 CLK4 Dual specificity protein kinase CLK4 1 S(1)IEDDEEGHLICQSGDVLR 59.547 0.012308 4715700.0 2614.4 2322.1 2559.4 3166.6 3748.9 2805.6 994.69 2901.1 2224.4 2170.0 True False 3445.7248171018136 3072.673413859546 2525.4606837177466 2436.5892934823046 3228.4299457243787 2630.165388482398 1083.21548303014 2452.8016556459456 2341.977242797398 2094.0289604965956 1.645500077651584 1.467350008918151 1.2060294921226102 1.163589109533839 1.541731278137988 1.256031047373222 0.5172877278513174 1.1713312957545094 1.1184072842249526 1.0 11.032065679593607 -7.01491942144176 24.62069611514483 0.954694896669635 1.3853665772034245 0.5052240137985284 0.2114942871691622 507.1410072719477 836905.794018561 0.08091834822777112 0.0650034228687364 9.66230135720352e-08 7.01491942144176 0.43067168053378946 S(ph)IEDDEEGHLICQSGDVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SIEDDEEGHLICQSGDVLR 19 0 A0A087WX74;B7ZL31;Q9HAZ1 A0A087WX74 CLK4 Dual specificity protein kinase CLK4 1 S(1)IEDDEEGHLICQSGDVLR 85.20299999999999 0.00074172 4111300.0 6014.2 8272.5 10732.0 8867.2 9316.3 6341.1 8969.7 9231.4 6417.5 4453.4 True False 7032.285274135448 9093.73912895213 10987.891581336651 8370.399531850277 7490.837892619129 6008.561553131433 8120.025080995647 8989.085531476805 6511.343796782802 5260.766166904999 1.3367416553077218 1.7285959574025573 2.0886485414349862 1.5910989514241665 1.4239062628830204 1.142145718418497 1.543506178259354 1.7087027338387177 1.2377177753584778 1.0 12.361057210548553 -6.15796777751368 3.772749649800583 1.377455030275303 1.7325867451744066 0.30466515728101007 0.25400119649773184 0.32264486730368375 8.331886361078874 0.07900601216184396 0.10421830609685068 6.950758868426859e-07 6.15796777751368 0.35513171489910356 S(ph)IEDDEEGHLICQSGDVLR ddPTM_PC-9_Lapatinib_30min_R1 1 SIEDDEEGHLICQSGDVLR 19 0 A0A087WX74;B7ZL31;Q9HAZ1 A0A087WX74 CLK4 Dual specificity protein kinase CLK4 1 S(1)IEDDEEGHLICQSGDVLR 84.895 0.00075212 3363300.0 2942.1 2151.8 3131.9 858.61 3136.9 1094.5 1121.8 2452.9 2364.2 2211.7 True False 2900.145114484937 2146.8176393061985 2874.4072714836116 921.7550436389952 2952.3937093826885 1047.6907864041152 1179.8813149904436 2566.870688751701 2097.9188998703057 2593.989398094994 1.1180250453663307 0.82761234139307 1.1081029373499192 0.35534264107475727 1.1381672228694935 0.403891699470141 0.4548520190009024 0.9895455589127662 0.8087615552365022 1.0 11.340956867818765 S(ph)IEDLHR ddPTM_PC-9_AZD4547_30min_R2 4 SIEDLHR 7 0 Q96PY5-3;Q96PY5 Q96PY5-3 FMNL2 Formin-like protein 2 1 S(1)IEDLHR;S(1)IEDLHR;S(1)IEDLHR;S(1)IEDLHR 154.49 0.00026962 72260500.0 67281.7 73965.5 91015.7 123052.0 114588.0 101573.0 89829.0 125040.0 93978.0 110468.0 True False 88675.88105370205 97873.4014008131 89808.77234939816 94684.26253444838 98679.43413285635 95221.62425303765 97823.60697816862 105717.94113335271 98945.48522011035 106600.5489438421 0.831852011385205 0.9181322457576976 0.8424794547419266 0.8882155248968624 0.9256934894851371 0.8932564156231602 0.9176651335041696 0.9917204196485483 0.9281892654439847 1.0 16.701855341769544 -7.317153017524341 0.35605046800462553 1.0030662342402803 0.8485951427072705 0.6625142580922986 0.030053435944514983 0.8552944000019173 0.27771860936062726 0.03643078881840342 0.04682271780675842 4.817780200394313e-08 7.317153017524341 -0.15447109153300975 S(ph)IEDLHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SIEDLHR 7 0 Q96PY5-3;Q96PY5 Q96PY5-3 FMNL2 Formin-like protein 2 1 S(1)IEDLHR;S(1)IEDLHR;S(1)IEDLHR;S(1)IEDLHR 167.23 0.0001639 59737100.0 84617.0 89268.0 102498.0 112783.0 155507.0 111766.0 111072.0 114402.0 104662.0 97253.0 True False 98940.98683806988 98129.9370883406 104941.9410458296 106464.13415741961 125036.5196663399 105904.7942072019 100550.45606835782 111399.06871893861 106192.48374894923 114884.19904567538 0.86122362918449 0.854163913780052 0.9134584383019203 0.926708242228262 1.0883700343911367 0.9218395139360857 0.8752331208609567 0.9696639715845417 0.9243436837360852 1.0 16.80982086053198 -5.532918596300893 2.3228428688817466 0.9575196720237087 0.8574705610820234 0.35917636501037886 0.053876194242124587 0.35947965664902254 3.8394528498327456 0.0162693260864687 0.038408580130687466 2.9314426602746968e-06 5.532918596300893 -0.10004911094168534 S(ph)IEDLHR ddPTM_PC-9_Lapatinib_30min_R1 4 SIEDLHR 7 0 Q96PY5-3;Q96PY5 Q96PY5-3 FMNL2 Formin-like protein 2 1 S(1)IEDLHR;S(1)IEDLHR;S(1)IEDLHR;S(1)IEDLHR 190.73 0.00016855 80075100.0 145163.0 141691.0 116171.0 101180.0 103986.0 81345.0 67795.0 79756.0 116428.0 70951.0 True False 143092.94900036638 141362.92319496916 106619.86881302789 108621.11472658538 97869.74792434191 77866.06397445663 71305.09337651735 83461.75492359276 103314.65259880725 83214.7858137352 1.7195615851329615 1.6987717003969767 1.2812611096744482 1.3053102722600132 1.176110074277062 0.9357239006629069 0.8568800926331043 1.0029678512952056 1.2415420118975349 1.0 16.344552272398133 -5.45215714348148 0.8593223559914377 1.0045851385961848 1.8675956856467488 0.8386453726674488 0.11363945628131157 0.41443003085962654 0.44884904374050555 0.049374814327663864 0.2816762364208139 3.5305539844005073e-06 5.45215714348148 0.863010547050564 S(ph)IEVENDFLPVEK ddPTM_PC-9_AZD4547_30min_R2 7 SIEVENDFLPVEK 13 0 Q5JPT2;Q96B97-2;Q96B97;Q5VSN0;Q5JPT1 Q5JPT2 SH3KBP1 SH3 domain-containing kinase-binding protein 1 1 S(1)IEVENDFLPVEK;S(1)IEVENDFLPVEK;S(1)IEVENDFLPVEK;S(1)IEVENDFLPVEK;S(1)IEVENDFLPVEK;S(1)IEVENDFLPVEK;S(1)IEVENDFLPVEK 186.72 9.408e-36 47390500.0 125561.7 137549.00000000003 174725.69999999998 221913.5 191372.3 187382.0 155417.90000000002 182905.0 155701.69999999998 167329.99999999997 True False 165487.70875439633 182009.02433270199 172408.72305425553 170754.77110439772 164803.55947135168 175664.9739180956 169249.79201563325 154641.23498877056 163931.77399067947 161471.82763128847 1.024870475438464 1.1271874914818516 1.067732530085315 1.0574895547371044 1.020633517864621 1.0878985919402384 1.0481691729042995 0.9576979294610131 1.015234523541829 1.0 17.300922950922185 -7.618265160317687 6.0294715560374845 0.9904865828655223 1.065246007062977 0.5227967361535683 0.03137154711421534 0.16102268517091403 8.42492928057826 0.014859361070661058 0.008450552089247165 2.4084344999046982e-08 7.618265160317687 0.07475942419745474 S(ph)IEVENDFLPVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SIEVENDFLPVEK 13 0 Q5JPT2;Q96B97-2;Q96B97;Q5VSN0;Q5JPT1 Q5JPT2 SH3KBP1 SH3 domain-containing kinase-binding protein 1 1 S(1)IEVENDFLPVEK;S(1)IEVENDFLPVEK;S(1)IEVENDFLPVEK;S(1)IEVENDFLPVEK;S(1)IEVENDFLPVEK;S(1)IEVENDFLPVEK 201.16 2.7789e-07 40766300.0 125437.0 129176.2 148780.0 179277.40000000002 204123.69999999998 185685.3 189316.09999999998 170200.1 164298.1 148051.8 True False 146671.00660631957 141999.9594402349 152327.4794512921 169233.06850317313 164127.12629924066 175947.6359877111 171382.70847812927 165732.52771691265 166700.64889103227 174892.41936259603 0.8386355860412317 0.8119274692280014 0.8709781705030843 0.967640959625073 0.938446199654679 1.0060335183706697 0.9799321726049758 0.9476255650241042 0.9531610889630375 1.0 17.416108232049687 -5.648133027952075 2.799784562407169 0.9699370056132495 0.8258411295919877 0.8886696744131836 0.021432704340817628 0.07942036128809148 1.2480433767578096 0.006239572608093707 0.012159277658900496 2.248365807511764e-06 5.648133027952075 -0.14409587602126173 S(ph)IEVENDFLPVEK ddPTM_PC-9_Lapatinib_30min_R1 7 SIEVENDFLPVEK 13 0 Q5JPT2;Q96B97-2;Q96B97;Q5VSN0;Q5JPT1 Q5JPT2 SH3KBP1 SH3 domain-containing kinase-binding protein 1 1 S(1)IEVENDFLPVEK;S(1)IEVENDFLPVEK;S(1)IEVENDFLPVEK;S(1)IEVENDFLPVEK;S(1)IEVENDFLPVEK;S(1)IEVENDFLPVEK;S(1)IEVENDFLPVEK 203.53 2.4256999999999996e-37 31793100.0 255578.3 226886.6 251093.6 214467.2 244448.1 257793.0 220496.69999999998 240603.2 257261.2 201547.0 True False 251933.70657468055 226361.25801757138 230449.65345732594 230239.83332960642 230070.14336145547 246767.7943348343 231912.94022736078 251782.50303716536 228285.73457546515 236384.13040550327 1.0657809648325498 0.957599216280982 0.97489477428964 0.9740071507111892 0.9732892938573477 1.0439270771329634 0.9810850661993578 1.0651413130198168 0.965740526590572 1.0 17.85077365820188 -6.734175379311824 24.99955298265055 1.0133693046352386 0.9857341854792945 0.07167751473311268 0.03835699157145806 496.17460392505154 454962.78533024114 0.012005612366271923 0.012003182235001908 1.844270504790002e-07 6.734175379311824 -0.027635119155944077 S(ph)IGASPNPFSVHTATAVPSGK ddPTM_PC-9_AZD4547_30min_R2 2 SIGASPNPFSVHTATAVPSGK 21 0 A0A087WU64;A6NMQ1;P09884 A0A087WU64 POLA1 DNA polymerase;DNA polymerase alpha catalytic subunit 1 S(0.896)IGAS(0.096)PNPFS(0.006)VHT(0.001)AT(0.001)AVPSGK;S(0.896)IGAS(0.103)PNPFS(0.001)VHTATAVPSGK 96.41 0.00018104 22958000.0 25461.0 26873.0 124423.0 232390.0 137648.0 121358.0 62627.0 156431.0 75655.0 106917.0 True False 33557.068378300646 35559.17171984305 122773.06972345604 178816.0758897091 118537.95117743078 113769.46507536591 68200.68167542512 132258.18337677105 79653.9688472563 103173.86837300203 0.325247748363787 0.3446528881837291 1.1899628429128728 1.7331527712350534 1.148914478508098 1.102696514819604 0.6610266994047448 1.2818961376791767 0.7720362733641546 1.0 16.654718089165463 -5.2582193349355535 24.27224643039784 1.1284551492755932 0.3349501637726652 0.5597974995692598 0.27500571687252673 133.80141877363153 1008556.5961996778 0.07470029371751183 0.1810395540421347 5.5179868994752155e-06 5.2582193349355535 -0.793504985502928 S(ph)IGASPNPFSVHTATAVPSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SIGASPNPFSVHTATAVPSGK 21 0 A0A087WU64;A6NMQ1;P09884 A0A087WU64 POLA1 DNA polymerase;DNA polymerase alpha catalytic subunit 1 S(0.361)IGAS(0.361)PNPFS(0.278)VHTATAVPSGK 53.097 0.014599 7525900.0 17483.0 22104.0 48079.0 49523.0 67194.0 63622.0 47186.0 41769.0 48745.0 33560.0 True False 20442.52659501015 24298.33903975314 49225.385700622865 46748.38686573225 54027.818056165 60285.550319870024 42716.20048294374 40672.60800791369 49457.803408520056 39644.16233918617 0.5156503603256559 0.6129108954771761 1.2416805601657563 1.179199763782723 1.3628190096164887 1.5206665184165318 1.0774903027960063 1.025941919517138 1.2475431561744368 1.0 15.274820822165983 -5.232393623874205 4.974646172504074 1.2202976307891877 0.5469182932253995 0.7476433157845761 0.14937586167559624 0.09341113290107128 6.350757385340317 0.041171434431441424 0.10919246684636252 5.856071574199415e-06 5.232393623874205 -0.6733793375637882 S(ph)IGASPNPFSVHTATAVPSGK ddPTM_PC-9_Lapatinib_30min_R1 1 SIGASPNPFSVHTATAVPSGK 21 0 A0A087WU64;A6NMQ1;P09884 A0A087WU64 POLA1 DNA polymerase;DNA polymerase alpha catalytic subunit 1 S(0.996)IGAS(0.004)PNPFSVHTATAVPSGK 97.124 0.00016898 3898800.0 24619.0 16100.0 49911.0 16551.0 31533.0 39762.0 23930.0 32434.0 46347.0 16527.0 True False 24267.928545428345 16062.721439181045 45807.51024203153 17768.21575251745 29678.290936263278 38061.47194974914 25168.978309610746 33941.00204613829 41126.91280445352 19383.669929156753 1.2519780121165152 0.8286728724687803 2.3632011073985666 0.9166590133579736 1.5310976221082595 1.9635844032041319 1.2984630052821824 1.751010111613824 2.121729938384411 1.0 14.24255412302424 -6.518208053406216 24.933731734614643 1.6638065375037332 1.3575727243971822 0.06881264071933124 0.4876329286314594 542.4071594804631 2895570.966812695 0.15450837097468081 0.15847602838196828 3.0324381143278107e-07 6.518208053406216 -0.30623381310655096 S(ph)IGSAVDQGNESIVAK ddPTM_PC-9_AZD4547_30min_R2 2 SIGSAVDQGNESIVAK 16 0 Q9H0H5;F8VRD2;F8W1E5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 S(0.991)IGS(0.009)AVDQGNESIVAK;S(0.998)IGS(0.002)AVDQGNESIVAK 158.91 4.7801000000000005e-05 40584000.0 49356.0 43095.0 55994.0 90565.0 81417.0 82059.0 62139.0 78674.0 61635.0 66578.0 True False 65050.18133142484 57024.61598134323 55251.48297417032 69686.63846530188 70113.65490971807 76927.83775786901 67669.25062080637 66516.7410486675 64892.900269653655 64247.12448476602 1.0124994986639322 0.8875823850274365 0.8599837489578432 1.0846654854074542 1.0913119532118998 1.1973740206242194 1.0532650474785341 1.0353263524570606 1.0100514348317762 1.0 15.9713442644489 -5.772064471953483 24.99925119396262 1.0747192009797752 0.9167779281639505 0.5279592112210305 0.06358930997821106 153.62891754737882 361465.9793655207 0.018775783293499153 0.028173419693240102 1.6901900006633736e-06 5.772064471953483 -0.1579412728158247 S(ph)IGSAVDQGNESIVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SIGSAVDQGNESIVAK 16 0 Q9H0H5;F8VRD2;F8W1E5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 S(1)IGSAVDQGNESIVAK;S(0.999)IGS(0.001)AVDQGNESIVAK;S(0.999)IGS(0.001)AVDQGNESIVAK;S(1)IGSAVDQGNESIVAK 248.01 3.8982e-47 34006300.0 79262.0 107497.0 96766.0 99258.0 153788.0 101885.0 117269.0 95392.0 101219.0 86436.0 True False 92679.491104141 118168.59173707647 99073.26842709877 93696.89605877774 123654.34537639542 96541.97124170809 106160.43136596307 92888.0610761785 102699.13638746536 102106.16257300049 0.9076777421527332 1.1573110648692941 0.9702966591880939 0.9176419297100645 1.211037044781593 0.9455058226547854 1.0397064064577297 0.9097204197618187 1.0058074243466053 1.0 16.639710416511527 -7.725573215220213 24.969930264284777 0.9683226991345782 1.024973959594135 0.05121344867168909 0.0963201868337482 482.09505742787485 335633.21522863436 0.043601095623671024 0.02517196978274533 1.881164544724634e-08 7.725573215220213 0.05665126045955671 S(ph)IGSAVDQGNESIVAK ddPTM_PC-9_Lapatinib_30min_R1 3 SIGSAVDQGNESIVAK 16 0 Q9H0H5;F8VRD2;F8W1E5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 S(1)IGSAVDQGNESIVAK;S(1)IGSAVDQGNESIVAK;S(0.575)IGS(0.425)AVDQGNESIVAK 273.32 3.42e-82 37069000.0 150352.0 128653.0 124959.0 85900.0 118382.0 125537.0 111193.0 95899.0 120491.0 89350.0 True False 148207.95290881983 128355.11188291656 114685.35337568894 92217.37255399972 111419.00350796679 120168.0751510402 116950.02946847263 100354.81763651139 106920.03475352045 104794.02844860888 1.4142786101738727 1.2248323094656302 1.0943882497267559 0.8799869030631191 1.0632190131196912 1.1467072783633925 1.1159989858184054 0.9576387044393996 1.0202874756928937 1.0 16.67719698355421 -4.991156644524899 1.9887246601766337 1.0333918599953524 1.4441712343926671 0.7364448044417147 0.07305820529365575 0.26868081346154954 1.592574499871758 0.021785979516639093 0.1742983029193979 1.0205713101546647e-05 4.991156644524899 0.4107793743973147 S(ph)IGSPESTPK ddPTM_PC-9_Lapatinib_30min_R1 2 SIGSPESTPK 10 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 S(0.715)IGS(0.276)PES(0.004)T(0.005)PK;S(0.902)IGS(0.097)PEST(0.001)PK 146.71 0.00014372 92911000.0 920370.0 844470.0 831080.0 768170.0 840910.0 867330.0 732400.0 774840.0 841330.0 630390.0 True False 907245.355024812 842514.6815990825 762751.8104615724 824663.7843399988 791449.3270926697 830236.3177449808 770320.0883392766 810841.8950924876 746570.5558023361 739352.0715581229 1.2270816434082183 1.1395311029879893 1.0316489799699033 1.115387128897994 1.0704633929337024 1.1229241787276352 1.0418853452535695 1.0966925315887812 1.0097632569406356 1.0 19.495901998396697 -4.929743327198195 2.936489024880082 1.068445773721376 1.2323007481067225 0.6211801838465995 0.040574486430603345 0.193071675144115 2.9228154650606286 0.009884093260117 0.06401971781181592 1.1755921375125923e-05 4.929743327198195 0.16385497438534657 S(ph)IHEVDISNLEAALR ddPTM_PC-9_AZD4547_30min_R2 4 SIHEVDISNLEAALR 15 0 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 S(1)IHEVDISNLEAALR;S(1)IHEVDISNLEAALR;S(1)IHEVDISNLEAALR;S(1)IHEVDISNLEAALR 211.45 8.5679e-14 12545700.0 21684.9 20355.7 25676.9 36375.2 30164.7 30150.3 28144.7 36626.1 29161.8 32517.100000000002 True False 28580.247126059952 26935.28194759088 25336.407529011583 27989.459631237776 25976.852085623024 28264.99697475082 30649.523776491573 30966.37782904896 30703.233213005344 31378.686226434933 0.9108171999241498 0.858394190031426 0.8074400357675574 0.8919895316604458 0.8278502132998437 0.9007705667083987 0.9767624927098102 0.9868602402786825 0.9784741461591036 1.0 14.937497329870606 -7.1565641972200105 2.837936816030704 0.9864607537202041 0.858200123712904 0.8187918275992616 0.028023899203533785 0.11124085404158829 1.7332899920878946 0.011912140959228464 0.00870799299089873 6.973259108522764e-08 7.1565641972200105 -0.12826063000730015 S(ph)IHEVDISNLEAALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 SIHEVDISNLEAALR 15 0 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 S(1)IHEVDISNLEAALR;S(1)IHEVDISNLEAALR;S(1)IHEVDISNLEAALR;S(1)IHEVDISNLEAALR;S(1)IHEVDISNLEAALR;S(1)IHEVDISNLEAALR;S(1)IHEVDISNLEAALR 152.94 1.4484000000000001e-10 11113200.0 22957.999999999996 26177.800000000003 29335.6 32457.54 32408.740000000005 28498.100000000002 29736.23 30837.01 27468.5 20874.739999999998 True False 26844.335958831034 28776.558980946855 30035.071959882538 30639.04926256447 26058.480045086704 27003.609467962156 26919.399022738227 30027.571162012842 27870.174847203478 24659.16511764907 1.0886149563765235 1.1669721518816094 1.218008469329151 1.242501484392733 1.0567462410329584 1.0950739548207624 1.0916589793006195 1.2177042904230968 1.1302156708969933 1.0 14.589836334966716 -6.265985084299303 24.997280222606577 1.1089317334997508 1.1809479855273728 0.2650701058632299 0.06422409135417839 636.3166945591416 3499165.1888966104 0.02050976051950826 0.02399850753228179 5.420195055630496e-07 6.265985084299303 0.07201625202762196 S(ph)IHEVDISNLEAALR ddPTM_PC-9_Lapatinib_30min_R1 5 SIHEVDISNLEAALR 15 0 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 S(1)IHEVDISNLEAALR;S(1)IHEVDISNLEAALR;S(1)IHEVDISNLEAALR;S(1)IHEVDISNLEAALR;S(1)IHEVDISNLEAALR 185.71 2.3390999999999998e-07 13800700.0 35537.7 28869.1 39210.2 30679.31 43132.7 38330.41 39941.5 38588.8 37900.0 38128.8 True False 35030.925881184 28802.2553726622 35986.488711749 32935.568800578 40595.719388150916 36691.10771684986 42009.475434739565 40381.776523340355 33631.302895306886 44719.31227656756 0.7833511764343439 0.6440674935816102 0.8047191890874748 0.7364954227580081 0.9077894386453398 0.820475670330816 0.939403432121922 0.9030053117453681 0.7520532222703552 1.0 15.448610381173875 -6.255654113222484 24.666105778762496 0.8815532833427108 0.7396204562059145 0.4804210001551582 0.0736993135373822 349.16391196705786 1488696.0274537753 0.02112208531577193 0.026517867782736005 5.550676115356565e-07 6.255654113222484 -0.14193282713679622 S(ph)IKYDSLLEQGLVEAALVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SIKYDSLLEQGLVEAALVSK 20 1 O96028;O96028-3;O96028-6;D6RIS1;D6R9V2;O96028-7;O96028-5 O96028;O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 S(0.988)IKY(0.012)DS(0.001)LLEQGLVEAALVSK 146.75 8.609899999999999e-05 1898100.0 10976.0 10176.0 10112.0 12084.0 12652.0 16719.0 16342.0 14944.0 13857.0 12824.0 True False 12834.020014118372 11186.206029158873 10353.108429973548 11406.972656856582 10172.931423141941 15842.226207882608 14793.967454165782 14551.735834476816 14059.632410131557 15148.889685271848 0.8471921230369739 0.7384175514879087 0.6834235805439335 0.752990674157905 0.671529837136007 1.0457681412311584 0.9765710729644345 0.9605810152954245 0.9280965603572059 1.0 13.886924436993345 -6.761225730672733 24.999999981426345 0.9793876684515086 0.7364162698264415 0.843961645103585 0.052337544632517934 2.2023898273570786 257721.1565618015 0.018145406374611574 0.017070750830749888 1.7329030628678435e-07 6.761225730672733 -0.24297139862506711 S(ph)IKYDSLLEQGLVEAALVSK ddPTM_PC-9_Lapatinib_30min_R1 1 SIKYDSLLEQGLVEAALVSK 20 1 O96028;O96028-3;O96028-6;D6RIS1;D6R9V2;O96028-7;O96028-5 O96028;O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 S(0.725)IKY(0.146)DS(0.129)LLEQGLVEAALVSK 92.147 0.00030119 2440300.0 7303.4 6268.4 8258.1 6963.4 7723.8 9036.2 8995.0 9543.2 9692.7 9694.1 True False 7199.252176720473 6253.88590492935 7579.150895187854 7475.511665221438 7269.501269575059 8649.742790411025 9460.71708712698 9986.611911164424 8601.006057344095 11369.712268423704 0.6331956347492139 0.550047860252174 0.6666088566055355 0.6574934781755777 0.6393742513400388 0.7607705970214692 0.8320981977179456 0.8783522111548534 0.7564840564374755 1.0 13.472908124177962 -7.302289066727107 0.2998343500543201 1.0098160352623005 0.5219099228215314 0.832670085251445 0.05265113807918464 0.7092458040448182 0.17870912489621374 0.08369294896637149 0.12545631343181088 4.9855254006209294e-08 7.302289066727107 -0.4879061124407691 S(ph)ILSPGGSCGPIK ddPTM_PC-9_AZD4547_30min_R2 2 SILSPGGSCGPIK 13 0 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347;P78347-5 A0A494C1K3 GTF2I General transcription factor II-I 1 S(0.923)ILS(0.077)PGGSCGPIK;S(0.99)ILS(0.01)PGGSCGPIK 203.88 1.0246e-09 148889000.0 190570.0 163416.0 239280.0 281120.0 225490.0 195773.0 203642.0 268780.0 207021.0 222370.0 True False 251167.2958977554 216237.026225947 236106.99085722526 216312.1272607039 194184.60574072172 183531.28336162152 221765.74349317266 227246.22694995624 217963.70741825204 214584.89398416074 1.1704798564072965 1.0076992010533052 1.1002964210269766 1.008049183912595 0.904931386992484 0.8552851971731459 1.0334639096708362 1.0590038410007094 1.0157458121648615 1.0 17.711188993489266 -1.5228792091061378 0.7744952573783526 0.9843438184146521 38.31236449946676 0.3892010374943269 0.06616587613510191 510.4438209504123 1.986322896329649 0.027019087974787668 33340.64485796983 0.029999967960065908 1.5228792091061378 37.32802068105211 S(ph)ILSPGGSCGPIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SILSPGGSCGPIK 13 0 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347;P78347-5 A0A494C1K3 GTF2I General transcription factor II-I 1 S(0.991)ILS(0.009)PGGSCGPIK 187.74 3.2532e-05 49312000.0 131270.0 135110.0 146170.0 150050.0 172710.0 148310.0 156450.0 144410.0 122200.0 109350.0 True False 153491.418299318 148522.8278891168 149655.24715281217 141643.1849686637 138868.7153091089 140532.36251516652 141629.92340008798 140619.39051504273 123986.94382031272 129174.28938587611 1.1882505336708338 1.1497862972208173 1.1585528967436722 1.0965276886141007 1.0750491910528193 1.0879282803357329 1.0964250244644564 1.0886020057364296 0.9598422751909439 1.0 16.978959421661614 -4.029492285044897 0.16982351082271152 0.9667794327658639 1.4426046185869899 0.7650061912805333 0.03189188802850007 12.959179377155914 0.30221774724484113 0.10150766646011551 1.368599861294746 9.34345966149881e-05 4.029492285044897 0.475825185821126 S(ph)ILSPGGSCGPIK ddPTM_PC-9_Lapatinib_30min_R1 1 SILSPGGSCGPIK 13 0 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347;P78347-5 A0A494C1K3 GTF2I General transcription factor II-I 1 S(0.977)ILS(0.023)PGGSCGPIK 186.16 4.1744e-05 86653000.0 167760.0 180630.0 188460.0 150530.0 182310.0 175730.0 183630.0 156790.0 167980.0 150310.0 True False 165367.71163658347 180211.76233287444 172965.5462766377 161600.4783533593 171586.88423525073 168214.43754663775 193137.4628915092 164075.03579003582 149060.32349218096 176290.88322451455 0.938038930952431 1.022240963552077 0.9811372154529292 0.9166695145973809 0.9733168335014066 0.9541868216316605 1.0955612641950394 0.9307063007965007 0.8455361999766363 1.0 17.427598342930025 -7.982928245236253 24.993567298591326 0.911219070498885 0.9827597689729076 0.16651874119991938 0.058099333111374295 331.55086642140327 485400.363592554 0.03097965384666925 0.014876882437885654 1.0400919971407898e-08 7.982928245236253 0.07154069847402267 S(ph)INKLDSPDPFK ddPTM_PC-9_Lapatinib_30min_R1 1 SINKLDSPDPFK 12 1 P42566;B1AUU8;P42566-2 P42566 EPS15 Epidermal growth factor receptor substrate 15 1 S(1)INKLDSPDPFK 64.675 0.020496 4021000.0 37625.0 54019.0 49203.0 37803.0 49326.0 43819.0 46835.0 50862.0 41785.0 42130.0 True False 37088.46060042003 53893.92232441747 45157.719269072506 40583.1587271112 46424.74165864721 41944.96351707804 49259.887134584984 53225.23420085979 37078.733284443246 49412.1143653037 0.7505944863282937 1.090702614463728 0.9138997561452551 0.8213200193596242 0.9395416944806116 0.8488801593669717 0.9969192326077508 1.0771697362991939 0.7503976253742193 1.0 15.59257717018761 -7.273342469233731 24.67736245680596 0.962552455610381 0.9027400106384271 0.06200428996410723 0.11411283643818089 2116.591093136097 4388078.280612498 0.04606467326815474 0.031330875422691286 5.3291449227380315e-08 7.273342469233731 -0.059812444971953926 S(ph)IPAGAEPGEK ddPTM_PC-9_AZD4547_30min_R2 2 SIPAGAEPGEK 11 0 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 S(1)IPAGAEPGEK;S(1)IPAGAEPGEK 75.695 0.021439 33217000.0 122809.0 249692.0 259005.0 302100.0 297256.0 283403.0 243805.0 306460.0 198952.0 280957.0 True False 161859.7074141128 330400.05600681156 255570.42446913946 232455.51239847313 255987.13541205315 265681.7656088105 265503.172687132 259103.64875021816 209468.196551442 271120.7809466556 0.5970022174211704 1.2186452652326176 0.9426441734815755 0.8573872928029443 0.9441811672208923 0.9799387737123875 0.9792800528240257 0.95567609330986 0.7726010371468203 1.0 18.048576171971256 -6.226507294677596 0.004452841446309686 1.8621448683728352 0.00024067535894926195 0.009136501523058782 0.1525354915129695 231093.62516474008 288.8783733637721 59334.647898580675 61455.76438053507 5.935983776636922e-07 6.226507294677596 -1.861904193013886 S(ph)IPAGAEPGEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SIPAGAEPGEK 11 0 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 S(1)IPAGAEPGEK;S(1)IPAGAEPGEK;S(1)IPAGAEPGEK;S(1)IPAGAEPGEK 138.2 9.900200000000001e-05 54756000.0 691885.0 633025.0 470514.0 533269.0 601099.0 557407.0 566410.0 591075.0 466409.0 441219.0 True False 809007.4651483484 695867.5384835199 481732.8381942807 503391.6668114253 483317.96597527544 528175.5956610574 512755.5443467171 575559.907545731 473229.349265861 521208.51201231714 1.5521762337013214 1.3351039410251904 0.9242612641423946 0.9658162812190013 0.9273025187352537 1.013367171656198 0.9837819846169353 1.104279562364725 0.9079463177582904 1.0 18.991501119620068 -5.076772717526979 3.0835037062201462 0.9811670928820346 1.5341361042667894 0.9191384651917179 0.05674337937479876 0.06543506591404752 1.155132830649705 0.015231990857230553 0.06104677964241477 8.379677070970657e-06 5.076772717526979 0.5529690113847547 S(ph)IPAGAEPGEK ddPTM_PC-9_Lapatinib_30min_R1 3 SIPAGAEPGEK 11 0 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 S(1)IPAGAEPGEK;S(1)IPAGAEPGEK;S(1)IPAGAEPGEK 122.34 0.00067847 50063000.0 429925.0 377430.0 382418.0 311322.0 302952.0 351354.0 379440.0 356293.0 354944.0 367482.0 True False 423794.1906614103 376556.08402423083 350977.06821617 334217.6584197473 285132.95898654877 336327.40846617747 399085.54658582126 372847.6734915454 314966.46899397916 431000.77406101505 0.9832794188936084 0.8736784402408597 0.8143304823078661 0.7754456106207213 0.6615602016208528 0.7803406135381208 0.9259508813070584 0.8650742549217856 0.7307793580653538 1.0 18.717330934778992 -10.155432250126136 15.33266049548956 0.999997405670441 0.821402890267822 0.26101465044537286 0.08909810601388393 0.0 0.0 0.09250249377121536 0.02243515014422122 6.991457948940896e-11 10.155432250126136 -0.17859451540261906 S(ph)IPLSIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SIPLSIK 7 0 Q9C0C9;K7ES11 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 1 S(1)IPLSIK 95.35799999999999 0.013152 16143000.0 59735.0 86693.0 62497.0 44942.0 59538.0 40878.0 36888.0 45951.0 29566.0 30106.0 True False 69846.95567997101 95299.30810592289 63987.1655011924 42424.04544392991 47871.9562971091 38734.28571839377 33393.70159400731 44744.834939108994 29998.34681662333 35563.97948103515 1.9639803165789587 2.6796581680838667 1.799212755010001 1.1928936542816575 1.346079853708084 1.0891437427312995 0.9389753925545603 1.2581503980163307 0.8435036588810385 1.0 15.118129145121356 -5.619327501557463 2.7044912900534857 1.099146790932725 2.325165143363736 0.8420219851345314 0.21618960414626612 0.09097272289819064 1.3357775869513422 0.058822558903910485 0.11886342482800354 2.402550352997824e-06 5.619327501557463 1.226018352431011 S(ph)IPMPASR ddPTM_PC-9_Lapatinib_30min_R1 1 SIPMPASR 8 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 S(0.818)IPMPAS(0.182)R 69.176 0.036617000000000004 7156900.0 66640.0 94423.0 74667.0 56401.0 63090.0 61579.0 81325.0 58380.0 58955.0 64115.0 True False 65689.70137972054 94204.36934483191 68528.16748295492 60548.917688220485 59379.17023971236 58945.40971766014 85535.61057371882 61092.54792666813 52314.86707632766 75197.19232213254 0.8735658786077617 1.2527644508491182 0.9113128478173944 0.8052018408990428 0.789646107867188 0.7838778004522775 1.1374840992373516 0.8124312363280478 0.6957023987307834 1.0 16.19839117578009 -5.5028100384987075 23.388848754407093 0.8581916843528329 1.067883631092916 0.23156519356091532 0.1454578692692576 436.00841365828217 508138.3340459764 0.03768862718686816 0.0766494543266243 3.1418826607628986e-06 5.5028100384987075 0.20969194674008318 S(ph)IPNGLHDPSSTYIR ddPTM_PC-9_AZD4547_30min_R2 1 SIPNGLHDPSSTYIR 15 0 A6NKD9 A6NKD9 CCDC85C Coiled-coil domain-containing protein 85C 1 S(1)IPNGLHDPSSTYIR 87.363 0.0029393 5325200.0 11259.0 10950.0 16732.0 24497.0 19066.0 18319.0 14298.0 19034.0 12907.0 22323.0 True False 14839.127798251733 14489.373361079215 16510.122747505404 18849.595124877167 16419.015003115837 17173.51003407794 15570.494301103805 16092.732657807368 13589.23766983726 21541.478564592395 0.6888630115967398 0.6726266870508747 0.7664340540970571 0.875037201757364 0.762204644118704 0.7972298643560122 0.7228145577108591 0.7470579426362544 0.6308405260618374 1.0 14.39482965657163 -11.44696099078183 2.488128932835919 1.16496364558183 0.7450803057856537 0.58832550159109 0.06505222176596533 12649528.153326996 6612742.068791953 12147365.278797805 0.01779974272138089 3.5730493056988705e-12 11.44696099078183 -0.4198833397961763 S(ph)IPNGLHDPSSTYIR ddPTM_PC-9_Lapatinib_30min_R1 1 SIPNGLHDPSSTYIR 15 0 A6NKD9 A6NKD9 CCDC85C Coiled-coil domain-containing protein 85C 1 S(1)IPNGLHDPSSTYIR 59.708999999999996 0.030461000000000002 4519200.0 19271.0 12373.0 18727.0 11556.0 12227.0 16597.0 15927.0 13200.0 15383.0 8963.0 True False 18996.192006131427 12344.35107869486 17187.338348310484 12405.866789685919 11507.831899206902 15887.184999496669 16751.62212859049 13813.320188969152 13650.404549828654 10512.242607553213 1.8070541858006932 1.1742833132318737 1.6349830373930971 1.1801351293749733 1.0947076022520963 1.5113031151013843 1.5935345819125393 1.3140222029354671 1.298524497524498 1.0 13.359782856048644 -13.164830783318433 0.22151600903751967 2.0921979006058128e-16 1.4471084024797185 0.25555930353743916 0.21580805076536858 122.06386133003085 2.093375013938539 55.8965868087708 0.421302899992051 6.841781756701653e-14 13.164830783318433 1.4471084024797183 S(ph)IQDLTVTGTEPGQVSSR ddPTM_PC-9_AZD4547_30min_R2 5 SIQDLTVTGTEPGQVSSR 18 0 O43318-3;O43318;Q9UG54;O43318-4;O43318-2 O43318-3 MAP3K7;DKFZp586F0420 Mitogen-activated protein kinase kinase kinase 7 1 S(1)IQDLTVTGTEPGQVSSR;S(0.997)IQDLT(0.003)VTGTEPGQVSSR;S(1)IQDLTVTGTEPGQVSSR;S(1)IQDLTVTGTEPGQVSSR;S(1)IQDLTVTGTEPGQVSSR 261.66 4.357299999999999e-66 441582300.0 80796.2 78348.5 118841.59999999999 162580.0 127114.4 100850.09999999999 93787.3 155679.1 102526.1 115097.9 True False 106487.71093463934 103673.12043657672 117265.68273427787 125099.69283596071 109466.75971425927 94543.9273043158 102134.18800992523 131622.47224482795 107945.42033481842 111068.35755407419 0.9587583113651003 0.9334172460964225 1.0557973964563803 1.126330627290093 0.9855800709123193 0.8512228809927852 0.919561522823462 1.185058239298685 0.9718827460130997 1.0 16.761088337951307 -5.243515365377722 23.974650142468228 1.012644779878348 0.9460877613177585 0.07785175035695724 0.09061432785252295 1447.1239989099802 1935617.1537302039 0.024883941889337083 0.06547561995965515 5.708008808282533e-06 5.243515365377722 -0.06655701856058949 S(ph)IQDLTVTGTEPGQVSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 SIQDLTVTGTEPGQVSSR 18 0 O43318-3;O43318;Q9UG54;O43318-4;O43318-2 O43318-3 MAP3K7;DKFZp586F0420 Mitogen-activated protein kinase kinase kinase 7 1 S(0.999)IQDLT(0.001)VTGTEPGQVSSR;S(1)IQDLTVTGTEPGQVSSR;S(1)IQDLTVTGTEPGQVSSR;S(1)IQDLTVTGTEPGQVSSR;S(1)IQDLTVTGTEPGQVSSR;S(1)IQDLTVTGTEPGQVSSR;S(1)IQDLTVTGTEPGQVSSR 307.23 5.752799999999999e-138 313668300.0 97642.0 91747.0 107489.8 108884.3 119597.0 88672.6 109860.9 88755.79999999999 92521.0 76515.7 True False 114170.86208259362 100855.03582520061 110052.76448933635 102783.86567866376 96162.82638424789 84022.45275680909 99454.08022796256 86426.05429454346 93873.94459246445 90387.39071205225 1.2631281994444175 1.1158086878123876 1.2175676675957183 1.1371482777515178 1.0638964752350744 0.9295815721075521 1.1003092294675718 0.9561737938632563 1.038573454250044 1.0 16.463833906327032 -6.25255045443858 2.399548894904745 1.0075904210755298 1.1893589426807936 0.6975013539230586 0.056009845073162715 0.16327422425367438 1.8522705663407077 0.017338081285563044 0.022212759650819168 5.590485759726657e-07 6.25255045443858 0.1817685216052638 S(ph)IQDLTVTGTEPGQVSSR ddPTM_PC-9_Lapatinib_30min_R1 7 SIQDLTVTGTEPGQVSSR 18 0 O43318-3;O43318;Q9UG54;O43318-4;O43318-2 O43318-3 MAP3K7;DKFZp586F0420 Mitogen-activated protein kinase kinase kinase 7 1 S(0.998)IQDLT(0.002)VTGTEPGQVSSR;S(1)IQDLTVTGTEPGQVSSR;S(1)IQDLTVTGTEPGQVSSR;S(1)IQDLTVTGTEPGQVSSR;S(1)IQDLTVTGTEPGQVSSR;S(0.965)IQDLT(0.035)VTGTEPGQVSSR;S(1)IQDLTVTGTEPGQVSSR 291.28 1.4722999999999998e-106 398925700.0 102761.3 105641.79999999999 120225.1 92603.6 109045.4 101121.4 92941.9 104389.40000000001 103940.29999999999 85693.7 True False 101295.90501788557 105397.19290271295 110340.65636030666 99413.97766055385 102631.563963505 96796.67344749662 97753.97681379055 109239.71261624074 92233.44887411795 100505.7418653221 1.0078618707538352 1.048668374031261 1.0978542550152346 0.9891372951982066 1.0211512502542544 0.9630959550271702 0.972620817473106 1.0869002167321165 0.9176933293792405 1.0 16.61691839896536 -5.793221704270946 24.985707093215964 0.995648511367823 1.0511822326247544 0.2558477348070787 0.04557061067589161 263.8587224713991 207431.7355345409 0.012447507402266654 0.018464768995782015 1.6098236217715115e-06 5.793221704270946 0.055533721256931456 S(ph)IQEDTK ddPTM_PC-9_AZD4547_30min_R2 1 SIQEDTK 7 0 Q8NDI1-3;Q8NDI1-2;Q8NDI1;H7BZ98 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 S(1)IQEDTK 81.771 0.023456 32254000.0 116760.0 84326.0 99182.0 110600.0 103050.0 100130.0 132310.0 126340.0 182050.0 157440.0 True False 153887.25124112883 111582.73041519322 97866.78187563232 85102.87875296632 88743.28627247906 93868.85527115136 144085.3336815672 106817.05600438055 191672.79133755906 151928.07352100615 1.0128954292298835 0.7344444501217569 0.6441652263964296 0.5601524246353303 0.5841138126470686 0.6178506255999665 0.9483786000988514 0.7030764856609046 1.2616021969834144 1.0 17.213028952488365 -8.251174584567883 24.59732669060734 1.1308010939014317 0.7168111925515933 0.5290805679761962 0.1527180384044109 386.1963919549446 925441.4640993705 0.10988751797298962 0.040487488301635864 5.608224824161197e-09 8.251174584567883 -0.4139899013498384 S(ph)IQEDTK ddPTM_PC-9_Lapatinib_30min_R1 2 SIQEDTK 7 0 Q8NDI1-3;Q8NDI1-2;Q8NDI1;H7BZ98 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 S(0.948)IQEDT(0.052)K;S(1)IQEDTK 88.134 0.017475 61074000.0 152844.0 231010.0 180086.0 190779.0 294370.0 212110.0 294570.0 250750.0 263810.0 235730.0 True False 150664.4165318435 230475.11053821235 165280.02423206292 204809.5240800873 277055.73535368766 203038.54975256 309821.3932579205 262400.7604078801 234096.93975754382 276475.61640951957 0.5449464892725919 0.8336182175169812 0.5978104918563517 0.7407869335454182 1.00209826440285 0.7343813982200024 1.120610190806153 0.9490918722438381 0.8467182126137162 1.0 18.076792722939203 -6.126543566722983 4.517944581792051 0.9375239858703853 0.67515912091465 0.5472190505837387 0.11832652474721785 0.18221387173816636 5.880695146458648 0.034230091660061475 0.04512046752276634 7.472336708734703e-07 6.126543566722983 -0.2623648649557353 S(ph)ISADDDLQESSR ddPTM_PC-9_AZD4547_30min_R2 1 SISADDDLQESSR 13 0 P18615;P18615-3;A0A0A0MT02;P18615-4;A2ABK4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 1 S(0.5)IS(0.5)ADDDLQESSR 206.67 7.0867e-10 140130000.0 37541.0 39765.0 42826.0 56921.0 53580.0 42401.0 45151.0 59412.0 51551.0 44389.0 True False 49478.257098691545 52618.25860304242 42258.099257988695 43798.74287068345 46141.3418581216 39749.658767123656 49169.35153092308 50231.24055194131 54275.88061654764 42834.95462096005 1.1550906855514862 1.2283953390088382 0.9865330693571206 1.022500041338944 1.0771889982473255 0.9279724729222266 1.1478791553770777 1.1726694004097789 1.267093220871286 1.0 15.386500939656663 -7.494554764587252 24.936868219198367 1.1639836940155406 1.0659796164832172 0.12892554343632456 0.09964495305825906 1240.221378301579 1091913.3895104595 0.04297358451910869 0.0289040269932198 3.2021762743490704e-08 7.494554764587252 -0.09800407753232343 S(ph)ISADDDLQESSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SISADDDLQESSR 13 0 P18615;P18615-3;A0A0A0MT02;P18615-4;A2ABK4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 1 S(0.956)IS(0.044)ADDDLQESSR 233.28 8.7626e-26 88259000.0 66728.0 65556.0 43992.0 77412.0 72864.0 72427.0 94642.0 95303.0 71011.0 67163.0 True False 78023.73246192503 72063.96643548919 45040.93612058908 73074.85661309015 58586.82225860047 68628.80061955338 85676.82461125695 92801.39723187544 72049.4015353866 79339.12023798464 0.9834206911783999 0.9083030693978835 0.5677014817593748 0.9210444531511783 0.7384354916321755 0.8650058182356357 1.079881203046641 1.1696801899681963 0.9081194916110503 1.0 16.275744779612253 -7.179203562412081 4.608467120962074 1.0533824218750192 0.8187184675449198 0.4043284055454405 0.12405709244149256 0.2147855355645956 8.201725748505789 0.049135434341991246 0.037328653334951924 6.619061824633128e-08 7.179203562412081 -0.23466395433009934 S(ph)ISADDDLQESSR ddPTM_PC-9_Lapatinib_30min_R1 2 SISADDDLQESSR 13 0 P18615;P18615-3;A0A0A0MT02;P18615-4;A2ABK4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 1 S(0.62)IS(0.38)ADDDLQESSR;S(0.933)IS(0.067)ADDDLQESSR 141.34 7.6748e-05 7497800.0 31384.0 38067.0 36525.0 27703.0 36855.0 33073.0 35968.0 34829.0 40654.0 36756.0 True False 30936.45840487929 37978.85820032951 33522.05549057727 29740.371034498898 34687.26135971788 31658.544886928554 37830.24704722438 36447.28248951565 36075.11841440126 43109.225625708576 0.7176296478503676 0.8809914269877415 0.7776074611413594 0.6898841397133091 0.8046366144659258 0.7343798091341426 0.8775441102951284 0.8454636324476212 0.8368305830315712 1.0 15.395709027058107 -8.800333836096867 0.5253460096607452 1.0056206075804768 0.7701921500762392 0.5861982983160853 0.05645222089136207 1.0145327812732248 0.590322350542485 0.0743339147264101 0.029200999787705535 1.5836753753401036e-09 8.800333836096867 -0.23542845750423758 S(ph)ISESFLTVK ddPTM_PC-9_AZD4547_30min_R2 2 SISESFLTVK 10 0 F5H527;Q76I76;J3KSQ9;K7EP00;Q76I76-3;Q76I76-4 F5H527 SSH2 Protein phosphatase Slingshot homolog 2 1 S(1)ISESFLTVK;S(0.999)IS(0.001)ESFLTVK 122.33 0.00054816 10901000.0 41892.0 38192.0 61722.0 72461.0 67588.0 59953.0 51167.0 67831.0 52210.0 58028.0 True False 55212.78459226939 50536.81711473399 60903.52595156166 55756.23596129011 58204.57285380222 56204.129432451235 55720.76387638683 57349.27755131512 54969.714011172466 55996.457382348584 0.986004957693516 0.9025002558584071 1.0876317681261012 0.9957100603808162 1.0394331279990883 1.0037086640800266 0.9950765902192831 1.0241590313424538 0.9816641369977135 1.0 15.773047937459241 -5.245802751482492 24.99983137937178 1.0157227749161342 0.9442526122183186 0.4132414899777279 0.034160044917189436 740.815337045821 1184410.6211047925 0.008107696698058525 0.02129084401176616 5.678024322121449e-06 5.245802751482492 -0.07147016269781559 S(ph)ISESFLTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SISESFLTVK 10 0 F5H527;Q76I76;J3KSQ9;K7EP00;Q76I76-3;Q76I76-4 F5H527 SSH2 Protein phosphatase Slingshot homolog 2 1 S(1)ISESFLTVK;S(0.991)IS(0.009)ESFLTVK;S(0.997)IS(0.001)ES(0.001)FLTVK 130.44 0.00015324 2859300.0 38487.1 37125.4 40613.1 52264.0 57935.0 46605.0 47776.0 54548.0 50009.0 35936.1 True False 45002.205875125284 40810.964358778976 41581.470330039476 49335.81752217416 46583.05263987733 44160.95175658647 43250.31141171366 53116.17279838345 50740.287017267 42451.03045998894 1.060096901947784 0.9613656939904965 0.9795161596661582 1.1621818596058413 1.097336204448156 1.0402798537060054 1.0188283050626545 1.2512340035761123 1.1952663213933257 1.0 15.373511953857147 -5.751407764860471 24.99378672003618 1.1126274180962126 0.9964301650891816 0.2891277448744669 0.0781133058615105 265.2068843483014 660757.7271134594 0.0224331783696858 0.0382666787905348 1.772524452589973e-06 5.751407764860471 -0.11619725300703099 S(ph)ISESFLTVK ddPTM_PC-9_Lapatinib_30min_R1 2 SISESFLTVK 10 0 F5H527;Q76I76;J3KSQ9;K7EP00;Q76I76-3;Q76I76-4 F5H527 SSH2 Protein phosphatase Slingshot homolog 2 1 S(0.998)IS(0.001)ESFLTVK;S(0.995)IS(0.004)ES(0.001)FLTVK 93.839 0.0065373 3403200.0 43673.0 35650.0 38111.0 33812.0 40114.0 40057.0 35153.0 32337.0 39872.0 31759.0 True False 43050.21501135267 35567.45461532946 34977.66069271431 36298.6472735255 37754.57338715838 38343.8554874277 36973.05033504999 33839.4950720224 35381.19548922631 37248.50083379256 1.155756984783041 0.9548694261290102 0.9390353949757327 0.9744995492703069 1.013586387157539 1.0294066775606017 0.9926050581210862 0.9084793834527309 0.9498689798846295 1.0 15.184894741146342 -7.5943877842557805 8.357531094655783 0.9471528147399817 1.0043877266933774 0.15360324343847354 0.05961311767550939 0.5229986595968209 54.50469906625917 0.028322838288607606 0.01629423976023695 2.5445571869116222e-08 7.5943877842557805 0.057234911953395695 S(ph)ISESSR ddPTM_PC-9_AZD4547_30min_R2 1 SISESSR 7 0 Q9H307 Q9H307 PNN Pinin 1 S(0.99)IS(0.01)ESSR 94.309 0.015632 0.0 33665.0 25381.0 48023.0 54306.0 53480.0 37819.0 43119.0 55285.0 44195.0 36150.0 True False 44369.76972449989 33584.91189749327 47386.18364232924 41786.590719336215 46055.22513199598 35454.17195145987 46956.507467428666 46741.97357291584 46531.057474119276 34884.39950320364 1.2719086570610212 0.9627487465968555 1.3583775073432893 1.1978589660257362 1.320224105556596 1.0163331591304563 1.3460603632611297 1.3399105112479648 1.3338643673612915 1.0 15.090294378987608 -5.2738435922933204 24.86132954056604 1.2485097812654158 1.1173286790849057 0.0994206421692958 0.14435651239727346 1296.5766910611992 2598685.626618801 0.036042644937426725 0.07584785416956694 5.3229992834012155e-06 5.2738435922933204 -0.13118110218051005 S(ph)ISGTSTSEKPNSMDTANTSPFK ddPTM_PC-9_AZD4547_30min_R2 1 SISGTSTSEKPNSMDTANTSPFK 23 1 Q9UJF2-2;Q9UJF2 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 S(0.561)IS(0.152)GT(0.152)S(0.04)T(0.043)S(0.043)EKPNS(0.006)MDT(0.002)ANTSPFK 51.963 0.037461 0.0 20566.0 20361.0 22839.0 26742.0 29890.0 30539.0 25648.0 28743.0 29241.0 29606.0 True False 27105.560200625725 26942.29506894373 22536.13993726251 20577.0450597814 25740.289438955886 28629.391502303934 27930.622313240336 24301.429798432106 30786.61956331537 28569.502951365062 0.9487585502193908 0.9430438854609621 0.7888180615401894 0.7202451192381778 0.9009708528277355 1.0020962405625615 0.9776376705183735 0.8506073710768207 1.077604311692947 1.0 14.802188316214403 -6.540883798779869 7.8429561386566435 0.9700899139114985 0.8472834481810878 0.3630112796176559 0.08175825152977745 0.21164737710442863 65.8573518312113 0.028370558941065018 0.028835105064956477 2.8781684036610666e-07 6.540883798779869 -0.12280646573041065 S(ph)ISGTSTSEKPNSMDTANTSPFK ddPTM_PC-9_Lapatinib_30min_R1 2 SISGTSTSEKPNSMDTANTSPFK 23 1 Q9UJF2-2;Q9UJF2 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 S(0.667)IS(0.225)GT(0.014)S(0.014)T(0.041)S(0.041)EKPNSMDTANTSPFK;S(0.94)IS(0.053)GT(0.005)S(0.001)TSEKPNSMDTANTSPFK 98.26700000000001 3.4498e-06 48627000.0 36687.0 46578.0 49198.0 44444.0 55046.0 49953.0 42903.0 43212.0 51009.0 45113.0 True False 36163.836652428174 46470.151502743814 45153.13034977196 47712.560020837744 51808.302504599924 47816.62663613046 45124.30741400877 45219.78727316178 45263.82927141716 52910.72194070606 0.6834878702459373 0.878274757899168 0.8533833728515823 0.9017559819785942 0.9791645361153538 0.9037228161376393 0.8528386262538041 0.8546431727738839 0.8554755560156915 1.0 15.691272482291314 -4.196507699489863 1.5383475242435931 0.8978604271567003 6.877679679842107e-15 0.623118378567626 0.05004056929850873 4.050774811305771 2.5238784422287535 0.014328544804775016 8.612299550599825 6.360515283511193e-05 4.196507699489863 -0.8978604271566935 S(ph)ISLGDSEGPIVATLAQPLR ddPTM_PC-9_AZD4547_30min_R2 1 SISLGDSEGPIVATLAQPLR 20 0 O43379;O43379-4 O43379 WDR62 WD repeat-containing protein 62 1 S(0.836)IS(0.164)LGDSEGPIVATLAQPLR 185.59 1.5364e-11 98545000.0 124600.0 97838.0 151710.0 170240.0 144210.0 147460.0 119520.0 153800.0 122520.0 128240.0 True False 164220.2081589987 129462.22017363166 149698.226274447 130993.798181781 124188.93074579554 138239.30288908386 130157.04845908009 130033.74397240604 128996.15707046255 123750.35663321815 1.3270281607812133 1.0461563400366014 1.209679150405484 1.0585326923140237 1.0035440230194832 1.117082056569819 1.051771097879343 1.0507747008585286 1.0423901843999719 1.0 16.917073157303676 -1.5228787452805534 0.8592246972053684 1.0554493648060816 92.84270508618494 0.6174237435550984 0.06028276469919148 477.0095982269945 1.2712120320528948 0.01982193879870623 85638.25089063682 0.029999999999985087 1.5228787452805534 91.78725572137886 S(ph)ISLTRPGSSSLSSGPNSILCR ddPTM_PC-9_AZD4547_30min_R2 1 SISLTRPGSSSLSSGPNSILCR 22 1 A0A087WZ32;A0A087X038;A8K727;Q9HB19 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 S(0.799)IS(0.184)LT(0.016)RPGSSSLSSGPNSILCR 55.208999999999996 0.0063082 42019000.0 2680.4 9619.7 5280.3 9623.5 2806.5 3875.7 5004.3 13210.0 5516.6 8965.3 True False 3532.711444216533 12729.079901513573 5210.27977191327 7404.950756592866 2416.865918716281 3633.351866317802 5449.673005386332 11168.698035601306 5808.196213637889 8651.427575824942 0.408338556065376 1.4713271064168636 0.6022450891772567 0.855922411843895 0.2793603596093012 0.4199713670921356 0.6299160407485337 1.29096590565128 0.6713569711740964 1.0 13.078722496790597 -10.09230112034394 13.291934734333951 0.9999634326042862 0.7481741245102381 0.0445483984024182 0.36240248207866516 0.0 0.0 0.3560019052608988 0.08634314460657751 8.085351027551563e-11 10.09230112034394 -0.2517893080940481 S(ph)ISLTRPGSSSLSSGPNSILCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SISLTRPGSSSLSSGPNSILCR 22 1 A0A087WZ32;A0A087X038;A8K727;Q9HB19 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 S(0.523)IS(0.466)LT(0.011)RPGSSSLSSGPNSILCR 52.465 0.011541 35996000.0 6623.3 2343.1 10052.0 7287.0 8135.7 9238.3 8508.2 5933.8 8674.4 2878.5 True False 7744.493873862075 2575.7074829915637 10291.677802422284 6878.733014772751 6541.567987611119 8753.827284902323 7702.241701966308 5778.044037380796 8801.246689647485 3400.3492638065386 2.277558354459289 0.7574832122121992 3.026653147653783 2.0229489623287455 1.9237929636346023 2.5743906304209485 2.265132521517508 1.6992501620002807 2.5883360816279457 1.0 11.731467223755335 -10.968644578459568 4.496907459879861 0.9964334406880118 2.108126167863467 0.2520932007992248 0.5811801830949237 0.020019550374575763 0.0024673644430681404 0.5420943095755957 0.1312367864758198 1.074868712509797e-11 10.968644578459568 1.1116927271754553 S(ph)ISLYYTGEK ddPTM_PC-9_AZD4547_30min_R2 2 SISLYYTGEK 10 0 P19338;H7BY16 P19338 NCL Nucleolin 1 S(0.975)IS(0.025)LYYTGEK;S(0.973)IS(0.025)LY(0.002)Y(0.001)TGEK 95.417 0.0059247 6297900.0 29300.0 33978.0 36466.0 56150.0 44892.0 44398.0 31190.0 37737.0 37266.0 45560.0 True False 38616.7905221401 44960.724023995346 35982.43701353886 43205.485008852236 38659.52069232544 41621.78604143196 33965.84957696378 31905.61375999139 39235.80467995312 43964.95826738474 0.8783538537050731 1.0226490777167259 0.8184344630717485 0.9827254866497641 0.8793257679720096 0.9467036403923745 0.7725664009594031 0.7257055395332984 0.8924335704205609 1.0 15.42406647885724 -7.251053886226489 24.488021302558845 0.8248185047633979 0.9221687144767097 0.12481891858776895 0.08757594698056148 789.2872215951642 1861068.057676413 0.03190547034441396 0.024417075882478247 5.609783668524308e-08 7.251053886226489 0.09735020971331176 S(ph)ISLYYTGEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SISLYYTGEK 10 0 P19338;H7BY16 P19338 NCL Nucleolin 1 S(0.894)IS(0.106)LYYTGEK 84.821 0.012299 3453500.0 11084.0 8046.4 9716.7 13848.0 15220.0 8701.3 13240.0 14171.0 10144.0 14336.0 True False 12960.302281021128 8845.19341519497 9948.38297878996 13072.141455821746 12237.750257684178 8244.988510236788 11985.811350700948 13799.026265415618 10292.336809437435 16935.00331628644 0.7652967075924437 0.5223024318329199 0.5874449973814043 0.7719007319738894 0.7226305202972768 0.4868607555752623 0.7077537055557681 0.8148227672412119 0.6077552284586367 1.0 14.047720648896401 -14.522878741747398 0.2515204303225091 3.0697905936403718 0.6346059457478884 0.4748523813569888 0.10535298483350955 162.9349968665733 1.6105462936702202 173.32755244170266 0.15158482795729653 3.0000000244046812e-15 14.522878741747398 -2.4351846478924832 S(ph)ISLYYTGEK ddPTM_PC-9_Lapatinib_30min_R1 1 SISLYYTGEK 10 0 P19338;H7BY16 P19338 NCL Nucleolin 1 S(1)ISLYYTGEK 132.56 0.00014227 3865900.0 23715.0 18909.0 18080.0 17430.0 21763.0 21128.0 15842.0 15669.0 18769.0 14780.0 True False 23376.819751201634 18865.217372265495 16593.53219081826 18711.860344775494 20482.94312770425 20224.404691773558 16662.221244498676 16397.038942496787 16655.037573667938 17334.70330688792 1.3485560922126014 1.0882919100651367 0.9572435072612314 1.0794450884740763 1.1816148661491876 1.1667003659495816 0.9612060240960666 0.9459082542232751 0.9607916143018197 1.0 14.081375523771506 -7.2703066729212775 24.087646874730993 0.9624688046590631 1.126006856957789 0.4378023541389304 0.09382702843928115 430.96544139957206 1170693.4307389483 0.041183863762870795 0.028248293393979676 5.366527103304357e-08 7.2703066729212775 0.16353805229872587 S(ph)ISNEGLTLNNSHVSK ddPTM_PC-9_AZD4547_30min_R2 1 SISNEGLTLNNSHVSK 16 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 S(0.5)IS(0.5)NEGLTLNNSHVSK 81.788 0.0039213 43870000.0 10933.0 8106.8 60360.0 130580.0 82859.0 65670.0 36162.0 102250.0 46984.0 74517.0 True False 14409.466579472966 10727.164562885562 59559.58696147664 100476.79844088921 71355.45810044979 61563.64451869091 39380.34794492351 86449.61197125139 49467.47832026294 71908.18251120948 0.20038702239799666 0.14917863570273587 0.8282727344998899 1.3972929774052665 0.9923134698798217 0.8561424078420282 0.5476476608038962 1.20222218045596 0.6879255822180133 1.0 16.133868325411157 -5.305552288900393 4.696221209176743 0.9535330303143436 0.16817000206430646 0.647166073162825 0.22672551916998201 0.11528092175159331 5.929426909599341 0.06130964927125066 0.14025834310345825 4.948205311185796e-06 5.305552288900393 -0.7853630282500371 S(ph)ISNEGLTLNNSHVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SISNEGLTLNNSHVSK 16 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 S(0.617)IS(0.326)NEGLT(0.057)LNNSHVSK;S(0.549)IS(0.451)NEGLTLNNSHVSK;S(0.571)IS(0.429)NEGLTLNNSHVSK 135.21 4.0212e-06 48543000.0 75398.0 105492.0 252762.0 235511.0 310606.0 339049.0 258376.0 256664.0 273075.0 184284.0 True False 88161.39222161946 115964.54858766013 258788.80468522347 222316.0822069637 249744.98400382715 321268.67357834725 233900.754799751 249926.8419579876 277068.2052678558 217693.23040865897 0.40497994382333696 0.5326970818980852 1.1887774562370126 1.0212356249646652 1.1472335797259283 1.4757862381630056 1.0744512099005876 1.1480689660804744 1.2727460782668192 1.0 17.731937019272493 -5.219033350868074 4.024277647126973 1.1758993528202222 0.4343195792508713 0.8213293836644994 0.13037521070021446 0.0828378775708816 2.922990617738636 0.034414374004450084 0.097510685856305 6.039022520022059e-06 5.219033350868074 -0.7415797735693509 down S(ph)ISNPPGSNLR ddPTM_PC-9_AZD4547_30min_R2 1 SISNPPGSNLR 11 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 S(0.681)IS(0.319)NPPGSNLR 87.641 0.010262 11613000.0 31977.0 30589.0 32895.0 55432.0 58013.0 43043.0 32736.0 71772.0 37516.0 54723.0 True False 42145.02083708105 40476.29604950244 32458.790806788835 42653.00881586277 49958.896327271534 40351.51440563438 35649.440581964926 60681.28655648582 39499.01916956805 52807.16442638485 0.7980928590822705 0.7664925108017853 0.6146664218647376 0.8077125382356527 0.946062847152418 0.7641295427230502 0.6750871963909665 1.1491108681110456 0.7479859901326675 1.0 15.688446054989782 -7.658389198133666 0.3928485236863939 0.9984913602963772 0.7269873625156442 0.21547398488184077 0.13464568451378026 1.7272717819772145 0.7195902356072171 0.16145184802405854 0.15120895601178508 2.1958911169730245e-08 7.658389198133666 -0.271503997780733 S(ph)ISNPPGSNLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SISNPPGSNLR 11 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 S(0.765)IS(0.234)NPPGSNLR 99.539 0.004520199999999999 9323100.0 59331.0 61774.0 61243.0 63541.0 67579.0 54323.0 67499.0 61565.0 46639.0 58606.0 True False 69374.56645933457 67906.5144698565 62703.265385370876 59981.003772701486 54337.380069910665 51474.20624982395 61105.00606955921 59948.9839835095 47321.00714268067 69230.80387515918 1.0020765696211564 0.9808713848290609 0.9057133801080929 0.866391843157889 0.7848728749112149 0.743515940427979 0.8826274237656859 0.8659293353232301 0.6835253166785775 1.0 16.079126479689812 -5.5296086942333735 1.6311882552646664 0.819742374054327 1.0014365193514345 0.3869711948161615 0.08064683589945879 0.39748491535987857 2.023944662082143 0.02387369931266781 0.07119788242058485 2.953869508227986e-06 5.5296086942333735 0.18169414529710748 S(ph)ISPEVSASR ddPTM_PC-9_Lapatinib_30min_R1 1 SISPEVSASR 10 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 S(0.861)IS(0.137)PEVS(0.002)ASR 125.23 0.00038651 23243000.0 100250.0 105180.0 121030.0 110090.0 106120.0 112210.0 91844.0 98065.0 104410.0 77988.0 True False 98820.41661640165 104936.46217224006 111079.38058931072 118186.38584947422 99878.23023994744 107411.03987428577 96599.23292385669 102621.45790388358 92650.2463139575 91468.1218875221 1.0803809521520584 1.1472462756071444 1.2144053938912673 1.2921046525346551 1.0919457859074357 1.1743002661229733 1.056097260230666 1.1219368648464947 1.0129238952548851 1.0 16.48098140810405 -7.762342927160119 0.8345537775621525 1.0035197893455707 1.1763063088894052 0.4881819128766216 0.06176025034519165 0.5485654896200247 0.7101996042711224 0.0579900440723608 0.025568117698531696 1.7284510025353663e-08 7.762342927160119 0.1727865195438345 S(ph)ISPEWK ddPTM_PC-9_AZD4547_30min_R2 1 SISPEWK 7 0 F5H6E2;O00159-2;O00159-3;O00159 F5H6E2 MYO1C Unconventional myosin-Ic 1 S(0.64)IS(0.36)PEWK 88.177 0.017446 4175000.0 38940.0 37896.0 42173.0 53721.0 51018.0 42714.0 42263.0 51029.0 42692.0 42557.0 True False 51322.109997683816 50145.14090332948 41613.75846465131 41336.4534311763 43935.03133478255 40043.08682764368 46024.325125720396 43143.64057976523 44948.61196255463 41067.09238334268 1.2497137493595893 1.221054084746184 1.013311536064101 1.006559048430292 1.0698354518179414 0.9750650582675693 1.1207105849156351 1.0505647728122294 1.0945165424174599 1.0 15.325695185336633 -5.228492107177816 7.0709073264059255 1.0433582767834968 1.2372293058903439 0.7646499985714562 0.04306155537013485 0.10048791740602837 16.981802460958367 0.0108806597340525 0.028430710095527285 5.908917042808132e-06 5.228492107177816 0.19387102910684706 S(ph)ISPEWK ddPTM_PC-9_Lapatinib_30min_R1 3 SISPEWK 7 0 F5H6E2;O00159-2;O00159-3;O00159 F5H6E2 MYO1C Unconventional myosin-Ic 1 S(0.969)IS(0.031)PEWK;S(0.899)IS(0.101)PEWK;S(0.588)IS(0.412)PEWK 87.639 0.017806 15954000.0 189047.0 175714.0 159993.0 140185.0 160182.0 136403.0 114958.0 119616.0 157268.0 114406.0 True False 186351.15511302635 175307.14502883574 146838.99313084 150494.67254345087 150760.40968992887 130569.3616609233 120909.962746186 125173.79603967657 139554.82173454174 134180.9246635872 1.3888051195073976 1.3064982632096065 1.0943358267875152 1.1215802314730265 1.1235606705491787 0.9730843783367966 0.9010965086827832 0.9328732556695899 1.0400496351059418 1.0 17.033820065130755 -4.6018847194083525 0.5138405406465995 0.9576693722793406 1.7924095822744663 0.8591874662808558 0.056024612024426865 1.9032557102578087 0.3367961818200628 0.03654596133176244 0.997076297923377 2.5010091498951932e-05 4.6018847194083525 0.8347402099951258 S(ph)ISPSALQDLLR ddPTM_PC-9_AZD4547_30min_R2 1 SISPSALQDLLR 12 0 Q92793;Q92793-2 Q92793 CREBBP CREB-binding protein 1 S(0.983)IS(0.016)PSALQDLLR 136.33 6.308e-05 2134600.0 2433.8 3528.2 3378.2 5778.4 4759.1 3049.2 3261.8 4906.1 4174.8 2870.0 True False 3207.697773815176 4668.6216522885525 3333.402860723331 4446.279155390055 4098.381113045662 2858.5330419733855 3552.0938810561215 4147.974975962419 4395.471404976882 2769.5221735600107 1.158213429175013 1.6857137656664412 1.2036021565548596 1.6054318675754455 1.4798152375062965 1.0321394315825094 1.2825656046256435 1.4977222481055321 1.5870865548358606 1.0 11.435421373824814 S(ph)ISPSALQDLLR ddPTM_PC-9_Lapatinib_30min_R1 2 SISPSALQDLLR 12 0 Q92793;Q92793-2 Q92793 CREBBP CREB-binding protein 1 S(0.99)IS(0.01)PSALQDLLR;S(0.626)IS(0.355)PS(0.019)ALQDLLR 180.95 0.00069427 9131200.0 31753.0 24260.5 31082.0 24073.3 25951.3 29159.0 22202.5 23273.6 28846.1 24492.3 True False 31300.196397212974 24204.32630281067 28526.55793998968 25843.730788174653 24424.895556218864 27911.937542948916 23352.036812333154 24354.976420453986 25597.14845510059 28725.76142106166 1.08962112225383 0.8425999905807237 0.9930653367842176 0.8996708706640616 0.8502784381656316 0.9716691973388023 0.8129301246375839 0.8478444161482513 0.8910868568424725 1.0 14.810057513807465 -4.751361438202018 24.999704868417687 0.8969654404111597 1.0896215144201642 0.4428987835869549 0.06331187829094628 382.29059019627914 948259.611086528 0.01525193110715317 0.20351178769742004 1.772713539760425e-05 4.751361438202018 0.19265607400900453 S(ph)ISSPNVNR ddPTM_PC-9_AZD4547_30min_R2 3 SISSPNVNR 9 0 Q9NQT8 Q9NQT8 KIF13B Kinesin-like protein KIF13B 1 S(0.472)IS(0.208)S(0.32)PNVNR;S(0.9)IS(0.093)S(0.007)PNVNR;S(0.972)IS(0.026)S(0.002)PNVNR 89.561 0.0092508 205227000.0 250434.0 323608.0 403303.0 520420.0 442571.0 409999.0 396036.0 503147.0 338245.0 388782.0 True False 330066.8026492027 428207.95750064985 397954.93870650104 400445.20940884936 381127.65598153655 384361.69771613687 431282.4367766081 425397.1923178426 356123.9401591467 375170.86051603087 0.8797772891935436 1.1413678474700002 1.0607298716087163 1.0673675691605014 1.0158775536493223 1.0244977373441648 1.1495627250565204 1.1338758871963768 0.9492313440050062 1.0 18.517188252659047 S(ph)ISSPNVNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SISSPNVNR 9 0 Q9NQT8 Q9NQT8 KIF13B Kinesin-like protein KIF13B 1 S(0.968)IS(0.01)S(0.022)PNVNR;S(0.994)IS(0.006)SPNVNR 104.07 0.0027276999999999996 52611000.0 107639.0 143837.0 141653.0 124100.0 155031.0 147543.0 135728.0 108432.0 110929.0 120611.0 True False 125860.1567328429 158116.18677438312 145030.54474199394 117147.07933762869 124653.78844934555 139805.5853453929 122870.86125437616 105585.77489320078 112551.1267679502 142476.8195438495 0.8833728682026583 1.1097678013911614 1.0179237942447086 0.8222185174590791 0.8749057485170868 0.9812514470283042 0.8623919431087574 0.7410733565729622 0.7899609713937418 1.0 17.120367691612728 -5.753178322214059 24.958470706138886 0.8614595172464442 1.0142961738640845 0.32135677265504814 0.09007712345139725 197.7143198483505 597331.9355227166 0.025157661479392347 0.042646522437996916 1.7653128307494097e-06 5.753178322214059 0.15283665661764034 S(ph)ISSPNVNR ddPTM_PC-9_Lapatinib_30min_R1 2 SISSPNVNR 9 0 Q9NQT8 Q9NQT8 KIF13B Kinesin-like protein KIF13B 1 S(0.984)IS(0.005)S(0.011)PNVNR;S(0.816)IS(0.092)S(0.092)PNVNR 102.05 0.0033025999999999997 70934000.0 189314.0 216211.0 222961.0 183210.0 225480.0 219730.0 186731.0 169912.0 196323.0 155780.0 True False 186614.34764406466 215710.37671346462 204630.0072343489 196683.87457064344 212217.70971073626 210332.66011564768 196399.0174982001 177806.7318142525 174211.03636715905 182706.3654361976 1.0213894146410119 1.180639635616813 1.119993858702242 1.0765025843575597 1.1615233503445956 1.1512059780374613 1.0749434866667744 0.9731830163100907 0.9535028292596341 1.0 17.47916737235 -7.654430145173151 3.3911045443706946 0.9708628410264732 1.121150944507224 0.6777205211661318 0.043962480417248546 0.13213838918497403 2.9620901116453897 0.02296478162744096 0.011983357963999465 2.216000503979133e-08 7.654430145173151 0.15028810348075083 S(ph)ITSPPSTSTTK ddPTM_PC-9_AZD4547_30min_R2 2 SITSPPSTSTTK 12 0 K7EN08;Q14938-6;Q14938-5;Q14938-3;Q14938-4;Q14938;C9JWJ8;Q14938-2 K7EN08 NFIX Nuclear factor 1;Nuclear factor 1 X-type 1 S(0.999)IT(0.001)SPPSTSTTK;S(0.993)IT(0.007)SPPSTSTTK 155.86 0.00034048 47882000.0 109991.0 117417.0 145571.0 182034.0 143511.0 152154.0 116424.0 146927.0 119347.0 125683.0 True False 144965.85004507558 155369.74903541902 143640.63342559824 140068.87369726447 123586.97483017693 142639.78632704285 126785.51045682667 124222.8081965781 125655.4387682706 121282.87642492805 1.1952705469910823 1.2810526400368658 1.1843438881045112 1.1548940611081615 1.0189977222932627 1.1760917165856826 1.045370246766077 1.0242402873209377 1.0360525943334555 1.0 16.888016349374162 -5.941607459577403 0.444246899334068 1.0076286942475488 1.3028139879345908 0.7165885737591571 0.04931065319090034 1.0552298214695164 0.3313476911810299 0.04286186962155573 0.14926480344500304 1.1439118011848771e-06 5.941607459577403 0.29518529368704205 S(ph)ITSPPSTSTTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SITSPPSTSTTK 12 0 K7EN08;Q14938-6;Q14938-5;Q14938-3;Q14938-4;Q14938;C9JWJ8;Q14938-2 K7EN08 NFIX Nuclear factor 1;Nuclear factor 1 X-type 1 S(0.988)IT(0.012)SPPSTSTTK;S(0.997)IT(0.002)SPPSTSTTK;S(0.998)IT(0.002)SPPSTSTTK 94.12200000000001 0.0050076999999999995 20236900.0 18764.9 21880.6 20263.0 30074.4 57091.0 66094.0 93979.0 91253.0 76783.0 56871.0 True False 21941.426946331063 24052.761364152302 20746.146767855433 28389.428870520358 45904.428381172664 62627.91428816274 85076.62877096124 88857.70544054553 77905.80611583535 67181.2621094117 0.3266003980484492 0.35802782813130046 0.30880852958773186 0.42257957024214887 0.6832921403949289 0.9322229491039724 1.2663743743367766 1.3226560896672568 1.1596359411789199 1.0 16.03577127875219 -6.678283094335854 1.479526892335084 1.2168991306040047 0.33458591540827926 0.9465023251416361 0.0892647357878699 0.07826590018894178 0.3562572829655684 0.03860060244173538 0.03750478010231747 2.0975721380141426e-07 6.678283094335854 -0.8823132151957254 down S(ph)ITSPPSTSTTK ddPTM_PC-9_Lapatinib_30min_R1 2 SITSPPSTSTTK 12 0 K7EN08;Q14938-6;Q14938-5;Q14938-3;Q14938-4;Q14938;C9JWJ8;Q14938-2 K7EN08 NFIX Nuclear factor 1;Nuclear factor 1 X-type 1 S(0.992)IT(0.008)SPPSTSTTK;S(0.851)IT(0.149)SPPSTSTTK 126.83 0.000252 27645000.0 38627.0 33779.6 36268.6 40537.8 90311.0 121619.0 127733.0 129877.0 133948.0 102358.0 True False 38076.17189667577 33701.38541161244 33286.735708844644 43519.085042136554 84999.08453825742 116417.63887773603 134346.38973763085 135911.55955929912 118861.36570502809 120050.443916538 0.31716810579348836 0.28072687040659733 0.27727290814506605 0.36250665655507347 0.7080280735767279 0.9697393452261819 1.1190828234757026 1.1321204247590133 0.9900951785539703 1.0 16.8732812127407 -6.495956478598854 1.74217035542882 1.0718610522951442 0.285401092912962 0.9825493255996411 0.046175504849789835 0.04200728526422329 0.2571097130589323 0.01819058602034518 0.02026646205265559 3.191857700654869e-07 6.495956478598854 -0.7864599593821822 down S(ph)ITSTPLSGK ddPTM_PC-9_AZD4547_30min_R2 3 SITSTPLSGK 10 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 S(0.763)IT(0.229)S(0.005)T(0.002)PLSGK;S(0.873)IT(0.127)STPLSGK;S(0.981)IT(0.019)STPLSGK 156.01 0.00030678 52680000.0 142844.0 119843.0 200442.0 209683.0 194576.0 188789.0 187587.0 211632.0 157716.0 184391.0 True False 188265.4206602247 158579.9060924031 197784.00811352386 161343.8239200563 167562.48102623914 176983.99398567248 204281.8795958288 178929.13721955934 166052.54577640456 177935.52721425198 1.05805413684213 0.8912211550729676 1.1115487233495105 0.9067544095664627 0.9417033441808241 0.9946523707576748 1.1480668464249593 1.0055841012801843 0.9332174882448341 1.0 17.44099506721507 -7.013492951626722 24.847965609402145 1.02920775234814 0.9786862581879494 0.04953482874585935 0.0793073455513294 1655.3375317565296 3048386.356577758 0.029128660830217503 0.023603031003750448 9.694090021758634e-08 7.013492951626722 -0.05052149416019058 S(ph)ITSTPLSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SITSTPLSGK 10 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 S(0.829)IT(0.006)S(0.163)TPLS(0.002)GK 113.22 0.0013379000000000002 28702000.0 84704.0 98716.0 98631.0 104750.0 148980.0 113420.0 142230.0 83588.0 112310.0 120380.0 True False 99042.71421974163 108515.87208868402 100982.73710015028 98881.19710408195 119788.43846187861 107472.05553550126 128756.94474397249 81393.90356880677 113952.32128035488 142203.94107244426 0.6964836098971785 0.7631003140299872 0.7101261493779959 0.6953477966810216 0.8423707357087501 0.7557600353758887 0.9054386522127306 0.5723744570999022 0.801330261460919 1.0 17.117601923127488 -11.624554761341248 1.5361613383107178 1.3594005097273085 0.7491611365483705 0.43182372887283016 0.08632357971387976 131081.35061859773 26929.164584013666 164374.28103953874 0.02305920116902092 2.3738060843680875e-12 11.624554761341248 -0.6102393731789381 S(ph)ITSTPLSGK ddPTM_PC-9_Lapatinib_30min_R1 4 SITSTPLSGK 10 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 S(0.575)IT(0.01)S(0.025)T(0.389)PLSGK;S(0.779)IT(0.018)S(0.201)TPLS(0.001)GK;S(0.999)IT(0.001)STPLSGK;S(0.997)IT(0.002)STPLSGK 120.77 0.0006782 82349300.0 262373.0 247928.0 282804.0 260011.0 306084.0 312007.0 294436.0 278128.0 337737.0 219133.0 True False 258631.51290668457 247353.93794865053 259552.9467750099 279133.076311269 288080.7409042975 298663.18793384114 309680.45539358724 291050.8422361824 299697.50253172225 257009.84707363095 1.0063097420255225 0.962429808682723 1.0098949504477561 1.0860793058691638 1.1208937874733065 1.1620690465150811 1.204936149021818 1.1324501592065421 1.1660934627374868 1.0 17.97146411032344 -5.895648280740128 1.8058888899398886 1.1443145001208581 0.9818427278613718 0.5844854906050012 0.05177851073971375 0.2150871988896656 1.4278072027324091 0.015872962696079407 0.02858836500171262 1.2716035136156762e-06 5.895648280740128 -0.16247177225948628 S(ph)IVAVEPR ddPTM_PC-9_AZD4547_30min_R2 1 SIVAVEPR 8 0 Q5VZL5-2;Q5VZL5-4;Q5VZL5;H7C1I7;Q5VZL5-3 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 S(1)IVAVEPR 104.42 0.0038583 4512800.0 19018.0 17566.0 14777.0 32542.0 24447.0 20442.0 12371.0 25958.0 17817.0 20891.0 True False 25065.32840102597 23243.865978147714 14581.04732487972 25039.944668888143 21052.956035936895 19163.758508467774 13471.995034197458 21946.78755549875 18758.770245873584 20159.612448725526 1.2433437629209276 1.1529917074183225 0.7232801405267849 1.242084625018233 1.0443135298103334 0.9506015334972023 0.6682665685395727 1.0886512630795246 0.9305124438073956 1.0 14.299180284077952 -6.766352776450158 4.334419801649359 0.9147509610289731 1.0760486361411266 0.1723929675888659 0.16891247363149578 0.3884839147404672 17.237497602700028 0.06043335287057346 0.05628117359159927 1.7125656290714956e-07 6.766352776450158 0.16129767511215343 S(ph)IVAVEPR ddPTM_PC-9_Lapatinib_30min_R1 1 SIVAVEPR 8 0 Q5VZL5-2;Q5VZL5-4;Q5VZL5;H7C1I7;Q5VZL5-3 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 S(1)IVAVEPR 110.53 0.0037604 3752500.0 13939.0 15848.0 18676.0 15081.0 19509.0 13158.0 17562.0 22019.0 19731.0 15360.0 True False 13740.227303900458 15811.304929698214 17140.53137144479 16190.107048741205 18361.518976169737 12595.26301279611 18471.27442847405 23042.083124311506 17508.687003358853 18014.9555340865 0.762712251934359 0.8776766004102141 0.9514612089390289 0.8987036919468128 1.0192375407992262 0.6991559312463653 1.0253300039250244 1.2790530113001426 0.971897319992285 1.0 14.136907470346511 -7.512477030255515 24.97802725873305 1.1057234095437634 0.8791002677527944 0.42734294214409607 0.1141564842912017 440.46959175781905 1057723.3231980472 0.048451409866229575 0.030249531005020626 3.0727198764826254e-08 7.512477030255515 -0.22662314179096898 S(ph)IVVIHPDTGR ddPTM_PC-9_AZD4547_30min_R2 2 SIVVIHPDTGR 11 0 K7EQ71;K7EKI8;O60437 K7EQ71 PPL Periplakin 1 S(1)IVVIHPDTGR;S(1)IVVIHPDTGR 79.81 0.009558 69769000.0 62744.0 74503.0 111097.0 121139.0 100943.0 115675.0 90978.0 125101.0 105646.0 96951.0 True False 82695.28684372568 98584.63776442783 109623.78119050986 93212.27512889316 86928.80685301163 108441.82396375178 99074.86575226075 105769.51498499305 111230.23187941633 93556.77499958758 0.883904846485893 1.0537413005617435 1.1717353573912004 0.9963177453402393 0.9291556581914547 1.1591017749834773 1.0589811988784084 1.130538274598064 1.1889062217023476 1.0 16.51355451088181 -6.778271989515162 24.996740989716457 1.1126313630659712 1.0181310378459882 0.24600542266896508 0.08667969374386159 397.32057516507064 590024.9657092317 0.03133431454439054 0.027707658096287224 1.6662033775290223e-07 6.778271989515162 -0.09450032521998297 S(ph)IVVIHPDTGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SIVVIHPDTGR 11 0 K7EQ71;K7EKI8;O60437 K7EQ71 PPL Periplakin 1 S(1)IVVIHPDTGR;S(1)IVVIHPDTGR;S(1)IVVIHPDTGR;S(1)IVVIHPDTGR;S(1)IVVIHPDTGR 109.6 0.0020407 46057600.0 101403.0 116141.0 133634.0 144548.0 170666.0 148676.0 154425.0 125659.0 123124.0 121716.1 True False 118568.52509945753 127670.71093087073 136820.3413697674 136449.4441909391 137225.22243613214 140879.16883086032 139796.74605981854 122360.58439671596 124924.45557227636 143782.26542588227 0.8246394278756022 0.88794477227571 0.9515800920545125 0.949000516765935 0.9543960239440643 0.9798090773822279 0.9722808695894543 0.8510130511178453 0.8688446742875473 1.0 17.13352621447013 -4.92335593752272 2.6153077638426723 0.9387059257234693 0.817439632477314 0.40188197498453937 0.044476452221091325 0.4024269747169745 4.523102018938397 0.012633281165044528 0.0945983313321402 1.1930099408462328e-05 4.92335593752272 -0.12126629324615534 S(ph)IVVIHPDTGR ddPTM_PC-9_Lapatinib_30min_R1 3 SIVVIHPDTGR 11 0 K7EQ71;K7EKI8;O60437 K7EQ71 PPL Periplakin 1 S(1)IVVIHPDTGR;S(1)IVVIHPDTGR;S(1)IVVIHPDTGR 76.311 0.011762 56246200.0 85423.9 100494.5 91782.4 100267.0 134251.1 119983.2 132031.5 131623.7 133539.2 104703.2 True False 84205.7395211752 100261.81115961344 84236.40536230966 107640.96966090698 126354.71424581786 114851.79823050002 138867.4450349091 137739.41761794063 118498.60906588302 122801.00861175539 0.6857088591788197 0.8164575543235046 0.685958578961101 0.8765479280485553 1.0289387332745594 0.9352675481160957 1.1308330982357722 1.1216472826653578 0.9649644608418916 1.0 16.905962884600946 -6.080148710640737 2.2593175413444255 1.0409142623174727 0.735821539909216 0.7957147741997754 0.06820200730998803 0.1332595207429708 1.3441751961927322 0.02204443165323146 0.032138746605870315 8.314790082202217e-07 6.080148710640737 -0.3050927224082568 S(ph)IYQVENLK ddPTM_PC-9_Lapatinib_30min_R1 1 SIYQVENLK 9 0 Q9NY30 Q9NY30 BTG4 Protein BTG4 1 S(0.906)IY(0.094)QVENLK 93.111 0.006509100000000001 9084500.0 34281.0 38884.0 38741.0 32444.0 39361.0 39060.0 41459.0 33144.0 32252.0 35480.0 True False 33792.146653634554 38793.96648702582 35555.86452458463 34830.039990011246 37045.863366703416 37389.49485330722 43605.54415955505 34683.991238120754 28619.440131383595 41612.67072587168 0.8120638753576828 0.9322633181269618 0.8544480299957922 0.8370056375246424 0.890254403778776 0.8985122608355247 1.047891024510579 0.8334959192262759 0.6877578302992734 1.0 15.344735263926419 -4.732288214838917 23.496113835446145 0.8845778830437107 0.81206300165796 0.05420677639842675 0.09328031307469942 5724.207634217971 4613232.362361799 0.023452136009554696 2.209968981707783 1.8523019552596347e-05 4.732288214838917 -0.07251488138575068 S(ph)IYYITGESK ddPTM_PC-9_AZD4547_30min_R2 1 SIYYITGESK 10 0 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 S(0.999)IY(0.001)YITGESK 78.903 0.019759 3080200.0 15127.0 14815.0 17003.0 16340.0 18551.0 18991.0 15496.0 16785.0 17022.0 15173.0 True False 19937.07133885371 19603.6590268848 16777.529110437168 12573.065450483447 15975.513863568764 17803.48976784617 16875.113980270282 14191.263930928686 17921.74816889826 14641.797888301759 1.3616545926223087 1.3388833240586788 1.145865366973941 0.8587104907744185 1.0910896315767746 1.2159360417118232 1.1525301816761764 0.969229601391163 1.2240128094663194 1.0 13.837805094734378 -5.316009547137795 3.9716647062118717 1.0773377536572433 1.3550226149494162 0.5110178343043329 0.10646470171224946 0.1735575594574084 5.641257122953732 0.029076019408604555 0.06919114843567531 4.8304818302790975e-06 5.316009547137795 0.27768486129217296 S(ph)IYYITGESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SIYYITGESK 10 0 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 S(1)IYYITGESK 81.625 0.040045 0.0 15397.0 15351.0 17546.0 15383.0 19558.0 17345.0 19926.0 19552.0 18093.0 15109.0 True False 18003.407995388163 16874.945828775337 17964.363183575548 14521.140382358895 15725.750298277744 16435.397665872595 18038.465028252805 19038.78071705641 18357.575896406895 17848.142097221807 1.0086992751021702 0.9454735253033448 1.0065116629910646 0.8135939473845413 0.8810861216039719 0.9208464150692124 1.0106634589748489 1.066709387080683 1.0285426794794728 1.0 14.123486284244878 -7.348332151679398 4.069554697872234 1.0358362345048084 0.926065133097385 0.4245278066368233 0.0554962676461292 0.23411311138002872 7.1206144573326435 0.02620905986429688 0.01724356315554343 4.484023172997955e-08 7.348332151679398 -0.10977110140742341 S(ph)IYYITGESK ddPTM_PC-9_Lapatinib_30min_R1 3 SIYYITGESK 10 0 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 S(0.995)IY(0.004)YITGESK;S(1)IYYITGESK;S(1)IYYITGESK 119.39 0.00079395 7198400.0 56589.0 59747.0 55061.0 55241.0 61173.0 55114.0 57313.0 56211.0 58273.0 49699.0 True False 55782.03048284838 59608.659492344734 50534.09712160643 59303.6074185739 57574.92441074539 52756.90269700907 60280.38670533724 58822.768268344356 51709.681098106026 58289.40593024511 0.9569840281028544 1.022632818795209 0.8669516581122914 1.0173994137037952 0.9877425149888345 0.9050856129867444 1.034156820494529 1.009150244878761 0.8871197136575205 1.0 15.830946077713733 -7.2718557955180865 24.872046819767657 0.983369203890738 0.9620506592431806 0.03683849014467144 0.05700250421780932 3177.9711078960636 7588231.386840087 0.023268414502045406 0.01590148678585429 5.347418872707028e-08 7.2718557955180865 -0.021318544647557447 S(ph)KDVEFQDGWPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SKDVEFQDGWPR 12 1 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 S(1)KDVEFQDGWPR;S(1)KDVEFQDGWPR 66.538 0.018411 9290100.0 39553.0 40793.3 31605.0 39820.0 45479.0 32759.0 31445.3 35279.2 36558.6 31235.3 True False 46248.541692640654 44842.989230472376 32358.58306262997 37589.01449818186 36567.716423733196 31041.0603710764 28466.573539742945 34353.158381402216 37093.20036292382 36898.012631501246 1.2534155200856674 1.2153226158361765 0.8769736025024883 1.0187273464720612 0.9910484011410939 0.8412664573857146 0.7714934087111224 0.9310300455606004 1.0052899253239436 1.0 15.171255492748655 -5.252351790861643 20.510825672173013 0.9236090323649128 1.2343699091066744 0.7156807556995685 0.07679703469798735 30.705951363826337 69297.56891989219 0.021253214653095095 0.05390631268184735 5.593043655359948e-06 5.252351790861643 0.31076087674176167 S(ph)KDVEFQDGWPR ddPTM_PC-9_Lapatinib_30min_R1 1 SKDVEFQDGWPR 12 1 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 S(1)KDVEFQDGWPR 80.245 0.006843500000000001 9509900.0 28795.0 31914.0 28019.0 28540.0 28211.0 27826.0 30327.0 23256.0 24007.0 27409.0 True False 28384.378019643715 31840.10509379033 25715.38597646775 30638.92680664905 26551.68444495998 26635.946845574155 31897.183668849346 24336.55866020201 21303.078855082662 32146.609129803208 0.882966471052416 0.9904654318352751 0.7999408544967483 0.9530998023130104 0.8259559923644899 0.828577183304845 0.9922410024663342 0.7570490113571424 0.6626850990430752 1.0 14.972378947596754 -6.32414980925441 0.6728821977357463 0.8262220710777314 0.9211823042839982 0.05416568535584054 0.10552170934145139 2.2886850433031674 2.2426578455925026 0.0698832757523971 0.12028974796454052 4.7407842438390145e-07 6.32414980925441 0.09496023320626679 S(ph)KGIAYVEFVDVSSVPLAIGLTGQR ddPTM_PC-9_AZD4547_30min_R2 1 SKGIAYVEFVDVSSVPLAIGLTGQR 25 1 G3XAC6;Q14498-2;Q14498;Q5QP23;H0Y4X3;Q14498-3;A0A0U1RQH7 G3XAC6 RBM39 RNA-binding protein 39 1 S(0.543)KGIAY(0.457)VEFVDVSSVPLAIGLTGQR 59.242 0.016585 0.0 1249.2 2066.2 1030.4 1207.1 2134.9 1039.0 1164.6 1075.2 2167.0 1252.8 True False 1646.419615025851 2734.058743256791 1016.7362227485999 928.8217445090916 1838.505986056436 974.0311657517864 1268.2471438708565 909.0525456380412 2281.5431959818193 1208.9398533226417 1.3618705765227634 2.2615341331849748 0.8410147286932507 0.7682944208980492 1.520758854134471 0.8056903435475024 1.049057271447554 0.7519419126928504 1.8872263907184812 1.0 10.239526754665443 -5.272364665802837 24.974589920563012 1.0631319401345571 1.8117023784080335 0.3499267222381761 0.3996017979545436 632.1761859460108 1445120.4013270799 0.09900316711103631 0.2093111027155353 5.341156879760887e-06 5.272364665802837 0.7485704382734764 S(ph)KPIPIMPASPQKGHAVNLLDVPVPVAR ddPTM_PC-9_AZD4547_30min_R2 1 SKPIPIMPASPQKGHAVNLLDVPVPVAR 28 2 O00429-4;O00429-5;O00429-3;O00429-9;O00429-2;O00429;O00429-8;O00429-6;O00429-7 O00429-4 DNM1L Dynamin-1-like protein 1 S(0.59)KPIPIMPAS(0.41)PQKGHAVNLLDVPVPVAR 46.132 0.0068373999999999996 1517600.0 5577.5 4498.4 3992.8 9158.8 7441.1 6018.9 5768.8 4960.2 3232.8 6556.7 True False 7351.028980793053 5952.419828993491 3939.8528631508234 7047.380162049434 6408.031707735513 5642.537231514366 6282.212024353594 4193.715064056744 3403.679208107994 6327.151928704159 1.1618227385127118 0.9407739684563864 0.622689783262045 1.1138313480474273 1.0127829677464246 0.8917973355303945 0.992897293307169 0.662812448841519 0.5379480762373742 1.0 12.62734052318222 -7.761699931892579 24.9999669358848 0.7002851475715031 0.9535254645442802 0.25788654725280147 0.17468803528172544 8.727653730869738 837092.0452741595 0.08776361509147712 0.04631360520593569 1.7310119582905005e-08 7.761699931892579 0.25324031697277716 S(ph)KPSPQKDQALGDGIAPPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKPSPQKDQALGDGIAPPQK 20 2 Q9H9J4-2;Q9H9J4;B4DP25;E5RJP3 Q9H9J4-2 USP42 Ubiquitin carboxyl-terminal hydrolase 42 1 S(0.768)KPS(0.232)PQKDQALGDGIAPPQK 57.173 0.0062247 9959000.0 76470.0 61396.0 56730.0 72443.0 69945.0 72137.0 78554.0 82131.0 77469.0 61467.0 True False 89414.86064865427 67490.98912797148 58082.65834972305 68384.2535733749 56239.77935438366 68354.00873006917 71112.79643829039 79975.14827498779 78601.83756805093 72610.48052749573 1.2314318814457528 0.9294937678096534 0.7999211398653207 0.9417959098546321 0.7745407955685831 0.9413793743478291 0.9793737201802678 1.1014270625120466 1.0825136674076468 1.0 16.14789018002631 -7.545939245469259 3.3253902508831166 1.0683226609194107 0.9238690208122337 0.175996464169761 0.11800109334351705 0.3887386917738021 8.993289736285917 0.061592873157846194 0.03463246372163377 2.8448590539916592e-08 7.545939245469259 -0.1444536401071771 S(ph)KPSPQKDQALGDGIAPPQK ddPTM_PC-9_Lapatinib_30min_R1 1 SKPSPQKDQALGDGIAPPQK 20 2 Q9H9J4-2;Q9H9J4;B4DP25;E5RJP3 Q9H9J4-2 USP42 Ubiquitin carboxyl-terminal hydrolase 42 1 S(0.852)KPS(0.148)PQKDQALGDGIAPPQK 57.708 0.0059173 14200000.0 100100.0 75176.0 80374.0 82533.0 81331.0 74412.0 63026.0 62714.0 90100.0 66325.0 True False 98672.55564390843 75001.93459079956 73765.95997261221 88602.75214201718 76547.27048289812 71229.5722228443 66289.17789141361 65627.921388713 79951.98920493803 77789.18787749283 1.2684610591295027 0.9641691427466397 0.9482803714159267 1.139011147430337 0.9840348327514287 0.9156744551057788 0.8521644164200538 0.8436637941518025 1.027803366849019 1.0 16.247282024741416 -6.542836519047738 4.000654246720225 0.9145225153451871 1.0629661755132194 0.32923077887494623 0.10012897470497888 0.2648627088177572 9.593930680428974 0.033596762373597794 0.03501119737721828 2.8652563319438114e-07 6.542836519047738 0.14844366016803223 S(ph)KQS(ph)PIST(ph)PTS(ph)PGSLRKHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKQSPISTPTSPGSLRKHK 19 3 A0A1B0GWD1;A8K340;O43602-2;O43602 A0A1B0GWD1 DCX Neuronal migration protein doublecortin 4 S(0.669)KQS(0.669)PIS(0.669)T(0.993)PT(0.092)S(0.454)PGS(0.454)LRKHK 58.09 0.034073 0.0 10285.0 7827.9 12471.0 11974.0 15278.0 11674.0 11169.0 12095.0 13121.0 8748.5 True False 12026.047361990462 8605.002179211166 12768.355936530868 11303.135600231773 12284.38557404067 11061.794889097526 10110.991463442519 11777.519065711807 13312.869802506757 10334.533796912101 1.1636758462760821 0.8326454147145265 1.2355038154063591 1.0937247700142105 1.1886734143451323 1.0703719303141401 0.9783693838674778 1.139627514618111 1.2881925846025648 1.0 13.335185688094777 -5.2772705814748555 24.98384065476452 1.123362752009535 0.9981605870019873 0.1547846746418038 0.11789529176719321 1274.2630379815641 2010964.258736683 0.02992550034689254 0.06260648106073731 5.281161134426194e-06 5.2772705814748555 -0.12520216500754777 S(ph)KS(ph)CLGSIMT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 SKSCLGSIMTPK 12 1 A0A2R8YDS4;P35228-2;P35228 A0A2R8YDS4 NOS2 Nitric oxide synthase, inducible 3 S(0.999)KS(0.98)CLGS(0.191)IMT(0.83)PK 63.216 0.037986 0.0 1144.4 1075.0 3153.1 4336.2 3114.2 3149.6 974.0 4455.3 4223.9 2211.6 True False 1508.2953950012677 1422.4727272292378 3111.287833801059 3336.5560836221716 2681.8470850048966 2952.655014101854 1060.684113111981 3766.8357576089684 4447.166730737241 2134.1725571586485 0.7067354464576902 0.6665218903962764 1.4578426769498445 1.5633956459754728 1.2566214835858447 1.3835127830679728 0.49700016503076644 1.7650099308858052 2.0837896709992467 1.0 11.059461113726272 -5.258187154430192 24.60239119430574 1.3745377615681333 0.6866285699720638 0.3189282123166618 0.40289675797544017 269.07302834894233 2035448.8496997415 0.10747973405141875 0.26062904228866557 5.518395788359253e-06 5.258187154430192 -0.6879091915960696 S(ph)KSATLLYDQPLQVFTGSSSSSDLISGTK ddPTM_PC-9_AZD4547_30min_R2 1 SKSATLLYDQPLQVFTGSSSSSDLISGTK 29 1 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 S(0.425)KS(0.425)AT(0.149)LLYDQPLQVFTGSSSSSDLISGTK 126.33 1.9029e-12 11549000.0 10050.0 21602.0 18442.0 17308.0 23614.0 15252.0 17581.0 25080.0 16939.0 14650.0 True False 13245.690947013933 28584.424049866044 18197.447030211257 13317.908005934356 20335.60370731027 14298.290028918424 19145.674941090092 21204.462281065913 17834.36095834612 14137.10795911295 0.9369448818897645 2.0219428282317233 1.2872114355242625 0.9420532151591495 1.4384557128745485 1.0114013467444432 1.3542851194503724 1.49991514122924 1.2615282425462329 1.0 13.787199396458737 -5.497324049237048 24.977293390296513 1.2329321924222185 1.523227168786652 0.10140958673452627 0.30157125353220005 1384.9058797845987 1353612.0976023786 0.07449001826509238 0.1540403253640868 3.1818225159103934e-06 5.497324049237048 0.2902949763644336 S(ph)KSATLLYDQPLQVFTGSSSSSDLISGTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKSATLLYDQPLQVFTGSSSSSDLISGTK 29 1 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 S(0.478)KS(0.351)AT(0.17)LLY(0.001)DQPLQVFTGSSSSSDLISGTK 95.801 6.5122e-11 13964000.0 59196.0 47850.0 46760.0 47148.0 92366.0 44736.0 39544.0 50623.0 37066.0 39857.0 True False 69216.71362570612 52600.23177036678 47874.93573828754 44506.450415878375 74267.54535487875 42389.96540677289 35798.106046232526 49294.19988950216 37608.02012801736 47082.7585921616 1.4701074383782902 1.117186701526952 1.016825206717132 0.9452812822927472 1.577383050092628 0.9003288395644267 0.7603230379154599 1.0469692380707005 0.7987641602265504 1.0 15.522911230313234 -6.931576309230021 24.999999953462954 0.8946821280545243 1.1968690185223563 0.4027697923610609 0.1957159810729478 56.89028316360735 20785.19067548013 0.06901572172859222 0.060866140227838435 1.1706408926982752e-07 6.931576309230021 0.302186890467832 S(ph)KSATLLYDQPLQVFTGSSSSSDLISGTK ddPTM_PC-9_Lapatinib_30min_R1 3 SKSATLLYDQPLQVFTGSSSSSDLISGTK 29 1 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 S(0.42)KS(0.42)AT(0.159)LLY(0.001)DQPLQVFTGSSSSSDLISGTK;S(0.334)KS(0.334)AT(0.332)LLY(0.001)DQPLQVFTGSSSSSDLISGTK;S(0.493)KS(0.357)AT(0.149)LLY(0.001)DQPLQVFTGSSSSSDLISGTK 116.85 2.2694e-08 9170300.0 85945.0 82347.0 33752.0 21687.0 38214.4 22644.6 24442.3 21083.9 49277.0 18656.8 True False 84719.40853961746 82156.33058088455 30977.040846487726 23281.934325711198 35966.70412440111 21676.14324514082 25707.8026969076 22063.53496456112 43726.9053501857 21881.603021376635 3.8717185599635067 3.7545846390058424 1.415665973659496 1.0639958280463524 1.643696034941518 0.9906103873635266 1.1748592034958802 1.008314379115952 1.998341040529247 1.0 14.417430811751062 -5.265506215133166 4.9830699630550255 1.2673874293613843 3.85413956885819 0.9156957227950944 0.3069731993684035 0.03994627404695551 3.137377900165118 0.07678489759333244 0.18764702537844222 5.426174859435327e-06 5.265506215133166 2.586752139496806 S(ph)KSDATASISLSSNLK ddPTM_PC-9_AZD4547_30min_R2 1 SKSDATASISLSSNLK 16 1 Q9UBF8-2;A0A0B4J1S8;Q9UBF8 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 S(0.603)KS(0.293)DAT(0.1)AS(0.004)ISLSSNLK 71.781 0.0082174 17359000.0 37780.0 64807.0 55586.0 53207.0 68678.0 59007.0 70356.0 78277.0 54162.0 59392.0 True False 49793.254127182736 85754.59538004201 54848.89332075284 40940.94818995549 59143.24516857178 55317.28296199778 76617.54770236812 66181.08827651515 57024.89274608552 57312.70415751788 0.8687995944203097 1.496258057277399 0.9570110872801688 0.7143433343754578 1.0319395330923988 0.9651836146129853 1.336833583908254 1.1547367943872175 0.9949782266311961 1.0 15.806567347389338 S(ph)KSDATASISLSSNLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKSDATASISLSSNLK 16 1 Q9UBF8-2;A0A0B4J1S8;Q9UBF8 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 S(0.77)KS(0.229)DAT(0.001)ASISLSSNLK 66.436 0.012608 19078000.0 44128.0 50296.0 41191.0 35689.0 47724.0 37297.0 44993.0 35551.0 34153.0 33061.0 True False 51597.99883227182 55289.05448531596 42173.149657737435 33689.461035299144 38372.8247896005 35341.07966238396 40730.937318888835 34617.82391939812 34652.42301387193 39054.697589268006 1.3211726633994123 1.4156825656872851 1.0798483219935715 0.8626225042018199 0.9825405689518159 0.904912388109119 1.0429203100546207 0.8863933420626687 0.8872792558351342 1.0 15.253208469046967 -5.417549448113196 3.566031588714807 0.9390545929781153 1.367379622129416 0.890121201407497 0.05960147889731661 0.06568914984243616 1.5157782897980194 0.015614411042037531 0.03539956331293678 3.823407184435073e-06 5.417549448113196 0.4283250291513008 S(ph)KSDATASISLSSNLK ddPTM_PC-9_Lapatinib_30min_R1 1 SKSDATASISLSSNLK 16 1 Q9UBF8-2;A0A0B4J1S8;Q9UBF8 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 S(0.497)KS(0.497)DAT(0.006)ASISLSSNLK 68.189 0.011168 13730000.0 54221.0 82223.0 82057.0 70580.0 94108.0 94015.0 90003.0 87238.0 89006.0 62631.0 True False 53447.79859708639 82032.61769526594 75310.59020917983 75770.68864797801 88572.75246344681 89994.1976096692 94662.91495193892 91291.39595797683 78981.20700526878 73456.68489943832 0.7276097290567366 1.1167481599199314 1.0252380748229994 1.0315016087604219 1.2057820548899298 1.2251328484653319 1.2886902680339003 1.2427922126210038 1.0752078876605102 1.0 16.164606168253652 -4.130752101162631 0.8017969090748395 1.1781290958431154 4.588156726136404e-18 0.5727050212249881 0.10175502044956146 4.684903667334648 1.0989853829135574 0.03786651987101736 6.284365085897956 7.400275683027143e-05 4.130752101162631 -1.1781290958431154 S(ph)KSDSYTLDPDTLR ddPTM_PC-9_AZD4547_30min_R2 1 SKSDSYTLDPDTLR 14 1 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 S(0.823)KS(0.153)DS(0.013)Y(0.003)T(0.009)LDPDTLR 52.5 0.04227 31777000.0 22251.0 18984.0 30140.0 31643.0 27252.0 26590.0 25151.0 25493.0 25983.0 26902.0 True False 29326.35515044846 25120.206747646356 29740.323906873862 24348.195229476583 23468.530203761315 24927.323096573622 27389.39027605693 21553.64262086177 27356.40833465418 25960.169168331508 1.129667336152159 0.9676441853965339 1.145613640420869 0.9379058769454649 0.904020696151329 0.960214201030021 1.0550543834463495 0.8302581728610149 1.0537839009164058 1.0 14.664012164177631 -5.780713724763359 24.99342145491959 0.957219112174585 1.0696419868508644 0.32331482225580976 0.07735381890292384 268.3718190002797 348002.1100424214 0.020594608729342455 0.030600945104657645 1.6568617622792885e-06 5.780713724763359 0.11242287467627943 S(ph)KSDSYTLDPDTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKSDSYTLDPDTLR 14 1 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 S(0.612)KS(0.385)DS(0.002)YTLDPDTLR 67.234 0.016413999999999998 7024400.0 39335.0 45018.0 44571.0 40098.0 45521.0 46540.0 51260.0 49464.0 47303.0 45570.0 True False 45993.63859833689 49487.08952640276 45633.741676458805 37851.439059469994 36601.486825232685 44099.360471012405 46404.28170973798 48165.62241144013 47994.71688651603 53831.480268078485 0.8544004060317592 0.919296465190241 0.8477147841598394 0.7031469108962161 0.6799271846688747 0.8192113657547492 0.8620287140284203 0.8947482434363196 0.8915734185183907 1.0 15.7161624769494 -8.223730079615963 0.9969313446809035 0.9881946831483662 0.8044243714049338 0.4308776722329396 0.06854788204202898 0.5667059354852239 1.1447943152343838 0.07487296011968293 0.026164696457067288 5.974064680979814e-09 8.223730079615963 -0.1837703117434324 S(ph)KSEEAHAEDSVMDHHFR ddPTM_PC-9_AZD4547_30min_R2 2 SKSEEAHAEDSVMDHHFR 18 1 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 S(0.5)KS(0.5)EEAHAEDSVMDHHFR;S(0.641)KS(0.359)EEAHAEDSVMDHHFR 69.069 0.0039809 25565000.0 31092.0 28391.0 56176.0 80950.0 82193.0 68351.0 50983.0 58470.0 57983.0 63924.0 True False 40978.60924622457 37567.83553373515 55431.06953525366 62288.22816503269 70781.92070445309 64077.00116487042 55520.38823284204 49434.805006934774 61047.86300535943 61686.04021695129 0.6643092845982951 0.6090168116093717 0.8985998994310747 1.0097621430385788 1.147454439537882 1.0387601625831397 0.9000478558451068 0.8013937161969122 0.9896544305754208 1.0 15.91265641854407 -5.364098512211279 3.6397744909989536 0.9798957667843092 0.6344288847795114 0.7158812555003116 0.08597661296209873 0.1372680353914899 3.299613021523875 0.02654041035744127 0.062115773423465456 4.32415733859908e-06 5.364098512211279 -0.3454668820047978 S(ph)KSEEAHAEDSVMDHHFR ddPTM_PC-9_Lapatinib_30min_R1 3 SKSEEAHAEDSVMDHHFR 18 1 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 S(0.738)KS(0.262)EEAHAEDSVMDHHFR;S(0.888)KS(0.112)EEAHAEDSVMDHHFR;S(0.495)KS(0.495)EEAHAEDS(0.01)VMDHHFR 94.176 0.00034127 58190000.0 219215.0 82335.0 198911.0 170654.0 218610.0 215626.0 132580.0 206510.0 334691.0 416708.0 True False 216088.95390089205 82144.35836614721 182557.30539866412 183204.46444505558 205751.78960379632 206404.1786287563 139444.3436810777 216105.20850181972 296994.5751275242 488735.422571492 0.44213892409094346 0.16807531145162938 0.3735299243057418 0.37485407438061547 0.4209880849667676 0.4223229360842237 0.2853166299004649 0.4421721825784133 0.607679659405248 1.0 18.898694146478377 -8.623110718790327 1.4644917246266997 0.9989438982974901 0.35315447201306466 0.8669331740376547 0.0771284067149429 0.17738039568742628 0.808257103491478 0.0740181381061985 0.021804246421122213 2.381712199588305e-09 8.623110718790327 -0.6457894262844255 down S(ph)KSISSSNPDLAVAPGSVDDEVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SKSISSSNPDLAVAPGSVDDEVSR 24 1 Q96HP0;K7ESB7;K7EKT0;K7EP20 Q96HP0 DOCK6 Dedicator of cytokinesis protein 6 1 S(0.2)KS(0.2)IS(0.2)S(0.2)S(0.2)NPDLAVAPGSVDDEVSR;S(0.351)KS(0.184)IS(0.184)S(0.184)S(0.096)NPDLAVAPGSVDDEVSR;S(0.413)KS(0.147)IS(0.147)S(0.147)S(0.147)NPDLAVAPGSVDDEVSR 120.4 4.6089e-09 12797700.0 90152.0 71358.0 55761.1 70852.0 81604.0 65087.0 70128.0 76753.0 66574.0 60891.0 True False 105412.95301683666 78441.950651407 57090.65609914935 66882.39214528329 65614.28199921554 61673.72314088496 63484.96815724744 74738.31507652563 67547.51880436589 71930.05628710923 1.4654924305366905 1.0905309226828004 0.7936968083449244 0.9298253831238757 0.9121956159371788 0.8574124131741806 0.8825930554516297 1.0390415208102608 0.9390722361560455 1.0 16.134307112600474 -4.836439957123377 3.019705965761546 0.9175406341394368 1.5200152875045656 0.8606201592463212 0.06663956998966196 0.1114230380323954 1.5954390883611507 0.01734997698952807 0.15320042704064188 1.45733717325287e-05 4.836439957123377 0.6024746533651288 S(ph)KSISSSNPDLAVAPGSVDDEVSR ddPTM_PC-9_Lapatinib_30min_R1 2 SKSISSSNPDLAVAPGSVDDEVSR 24 1 Q96HP0;K7ESB7;K7EKT0;K7EP20 Q96HP0 DOCK6 Dedicator of cytokinesis protein 6 1 S(0.272)KS(0.092)IS(0.092)S(0.272)S(0.272)NPDLAVAPGSVDDEVSR;S(0.291)KS(0.291)IS(0.291)S(0.095)S(0.031)NPDLAVAPGSVDDEVSR 131.31 2.727e-07 12262200.0 113122.0 93054.0 89571.0 67476.0 92448.0 92088.0 101923.0 91595.0 113638.0 79378.0 True False 111508.85953596569 92838.53918022095 82206.81813405872 72438.41013333743 87010.3903997612 88149.61090761264 107200.07422693088 95850.8380839872 100838.89177880954 93098.38153546357 1.1977529329388943 0.9972089487383446 0.8830101745941096 0.7780845266976394 0.9346069068517233 0.9468436449030447 1.1514708683318582 1.029565031132954 1.0831433384306193 1.0 16.506468467085867 -7.227823673976346 21.65754675295278 1.0685085127574294 0.9457013197926115 0.2018819772108975 0.10565981172085594 199.9542634416141 128823.67848093016 0.04318377218845904 0.033444371180028694 5.918018603185061e-08 7.227823673976346 -0.1228071929648179 S(ph)KSLCHDEIENLLDSDHR ddPTM_PC-9_Lapatinib_30min_R1 1 SKSLCHDEIENLLDSDHR 18 1 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4;P30305-3 G8JLH2 CDC25B M-phase inducer phosphatase 2 1 S(0.5)KS(0.5)LCHDEIENLLDSDHR 78.244 0.0019248000000000002 5683000.0 26168.0 25853.0 41361.0 26907.0 37020.0 37493.0 27212.0 28701.0 36560.0 26532.0 True False 25794.83952137652 25793.13896690359 37960.45823807711 28885.83053912074 34842.55638412036 35889.511790451805 28620.904210661396 30034.55323815181 32442.227806132458 31118.020848332253 0.828935736212124 0.8288810876700069 1.219886650988974 0.9282669575905517 1.1196906305173235 1.1533352961416015 0.9197533593205788 0.9651819884220396 1.0425543438078637 1.0 14.925462685275376 -5.214610722182071 23.180844079240437 1.0404369845647743 0.8289076655246531 0.46227655454563255 0.09256292924605178 160.50370142643646 79450.04681744793 0.02339359910267834 0.061892797075674716 6.100834977083346e-06 5.214610722182071 -0.21152931904012118 S(ph)KSPASTSSVNGTPGSQLSTPR ddPTM_PC-9_AZD4547_30min_R2 1 SKSPASTSSVNGTPGSQLSTPR 22 1 Q5VZY9;O15075-2;O15075 Q5VZY9 DCLK1 Serine/threonine-protein kinase DCLK1 1 S(0.796)KS(0.197)PAS(0.006)T(0.001)SSVNGTPGSQLSTPR 74.742 0.00043887 5581500.0 6057.1 5783.9 7521.1 8298.9 8843.4 6952.6 7273.5 10664.0 8312.1 7265.1 True False 7983.131804493341 7653.432564670871 7421.365299800565 6385.716821726868 7615.646558195459 6517.8528229122885 7920.827409363445 9016.12383434158 8751.460636511525 7010.751060324338 1.1386985125847584 1.0916708493592984 1.058569222604408 0.9108463225666789 1.0862811263253065 0.9296939467439532 1.1298115339153127 1.286042501974741 1.248291454254925 1.0 12.775353292801404 -7.518021921501521 23.95584542543316 1.2018856327164695 1.0355896967743023 0.30275331733560373 0.09676916353452382 129.96624899841788 641065.1605780205 0.04333936756582647 0.025941074937725992 3.033738048995712e-08 7.518021921501521 -0.16629593594216718 S(ph)KSPASTSSVNGTPGSQLSTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SKSPASTSSVNGTPGSQLSTPR 22 1 Q5VZY9;O15075-2;O15075 Q5VZY9 DCLK1 Serine/threonine-protein kinase DCLK1 1 S(0.488)KS(0.488)PAS(0.022)T(0.001)S(0.001)SVNGTPGSQLSTPR;S(0.528)KS(0.449)PAS(0.021)T(0.002)SSVNGTPGSQLSTPR 74.382 0.0004516999999999999 10974600.0 12755.0 11163.6 10066.5 13467.099999999999 12075.6 12881.4 16364.199999999999 10364.8 10517.8 8988.2 True False 14914.169577266743 12271.848430337855 10306.52353741385 12712.582047927284 9709.47286541992 12205.876707591304 14814.064509451695 10092.734982413369 10671.602927277303 10617.68950944795 1.4046530145749367 1.155792738092217 0.9706936267295051 1.1973021095234735 0.9144619323045876 1.1495793596836803 1.3952248741376059 0.9505584970659144 1.0050776977214657 1.0 13.374182238354926 -4.79988297761325 3.601991628133732 1.0829968688706726 1.4346681992012686 0.344967791293196 0.13673847221226518 0.31106532780284335 6.8604298633539615 0.03504088473684212 0.28760803287520564 1.585320305817706e-05 4.79988297761325 0.35167133033059605 S(ph)KSPASTSSVNGTPGSQLSTPR ddPTM_PC-9_Lapatinib_30min_R1 2 SKSPASTSSVNGTPGSQLSTPR 22 1 Q5VZY9;O15075-2;O15075 Q5VZY9 DCLK1 Serine/threonine-protein kinase DCLK1 1 S(0.496)KS(0.496)PAS(0.006)T(0.002)SSVNGTPGSQLSTPR;S(0.774)KS(0.22)PAS(0.004)T(0.001)SSVNGTPGSQLSTPR 95.624 7.621800000000001e-05 11706400.0 29943.0 22593.9 24629.8 22411.0 21852.0 22422.0 18408.3 20290.0 24674.0 21484.6 True False 29516.007329126325 22541.58521271508 22604.832917777407 24059.179700904395 20566.70832268496 21463.063328234875 19361.391701496337 21232.747472286675 21894.95429126127 25198.184483569996 1.1713545215279968 0.8945717985124245 0.897081808910339 0.9547981409768522 0.816198021571558 0.8517702274237045 0.768364550792164 0.8426300508328721 0.8689099925249562 1.0 14.62103217157205 -2.137860236563789 1.1780492987360578 0.8596096165542889 199.99999999928914 0.6476713513583827 0.0642533675595483 592.16950876973 1.7268896015118707 0.019260064281876512 317587.6178106305 0.0072801405428998345 2.137860236563789 199.14039038273486 S(ph)KSPLPPEEEAK ddPTM_PC-9_Lapatinib_30min_R1 1 SKSPLPPEEEAK 12 1 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 S(0.5)KS(0.5)PLPPEEEAK 53.169 0.043264 6347700.0 89416.0 52950.0 46507.0 36931.0 45215.0 48305.0 33390.0 34844.0 39673.0 32211.0 True False 88140.91144311396 52827.39752823833 42683.37398221158 39647.028938204494 42555.54259611026 46239.10775445478 35118.77082147525 36462.97944427586 35204.60896478919 37778.62843154038 2.3330892386110933 1.398340800645217 1.1298285764809914 1.0494565468423473 1.1264448806876683 1.2239488217060566 0.9295935898020986 0.965174781566021 0.9318657247862866 1.0 15.205282704596689 -4.256601076153421 1.253403720145636 1.0328625733904722 5.171868074499221 0.9529217820936455 0.08668667068493835 0.9623986036593289 0.5278917766726475 0.028253591427713966 7.095725525153883 5.53858625850079e-05 4.256601076153421 4.139005501108748 up S(ph)KSPLPPEEEAKDEEEDQTLVNLDTYTSDLHFQVSK ddPTM_PC-9_AZD4547_30min_R2 1 SKSPLPPEEEAKDEEEDQTLVNLDTYTSDLHFQVSK 36 2 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 S(0.482)KS(0.482)PLPPEEEAKDEEEDQT(0.032)LVNLDT(0.002)Y(0.001)T(0.001)S(0.001)DLHFQVSK 41.603 0.015003 2020600.0 5469.6 4880.0 4781.8 7590.6 6774.9 6100.7 4633.6 5083.2 5170.0 6646.3 True False 7208.819025252477 6457.364566398769 4718.390207627383 5840.704443600953 5834.322078286455 5719.222264583178 5045.9814235273925 4297.708240315563 5443.2756452358135 6413.615059976278 1.1239868557498274 1.0068213489605118 0.7356834115399552 0.9106727468022623 0.9096776192096621 0.8917314511551512 0.7867608792140476 0.6700913915359707 0.8487063215259362 1.0 12.646922051642646 -5.045437701704465 4.406057961675823 0.8371682907266179 1.1047381907312834 0.5059867041447128 0.09050990243856201 0.15127623087403863 6.405881981284693 0.02393367204251249 0.07929634891600248 9.006629509969571e-06 5.045437701704465 0.2675699000046655 S(ph)KSPPKVPIVIQDDSLPAGPPPQIR ddPTM_PC-9_AZD4547_30min_R2 3 SKSPPKVPIVIQDDSLPAGPPPQIR 25 2 Q7Z422-4;Q7Z422-5;Q7Z422;Q7Z422-2;Q7Z422-3 Q7Z422-4 SZRD1 SUZ domain-containing protein 1 1 S(0.5)KS(0.5)PPKVPIVIQDDSLPAGPPPQIR;S(0.5)KS(0.5)PPKVPIVIQDDSLPAGPPPQIR;S(0.605)KS(0.395)PPKVPIVIQDDSLPAGPPPQIR 83.727 4.8562999999999996e-06 292847000.0 316707.0 357044.0 357527.0 417645.0 378628.0 409067.0 407395.0 399585.0 364752.0 371626.0 True False 417413.2380851673 472451.49062403326 352785.95837600844 321363.39780092787 326062.0377950143 383487.9758234699 443652.36577131075 337838.3197998288 384032.0460640334 358615.4868541516 1.163957646522189 1.317431923446682 0.9837443482174153 0.8961224754122956 0.909224642402639 1.069356985074752 1.2371255063832298 0.9420628282493198 1.0708741260251784 1.0 18.452078266952185 -5.268732655653504 24.965411763637878 1.0135508937559725 1.2406947885440984 0.4546224295780096 0.09950832654298553 467.59265775008646 1600608.099934646 0.02787811923237616 0.05999945110912651 5.38601234308976e-06 5.268732655653504 0.2271438947881259 S(ph)KSPPKVPIVIQDDSLPAGPPPQIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SKSPPKVPIVIQDDSLPAGPPPQIR 25 2 Q7Z422-4;Q7Z422-5;Q7Z422;Q7Z422-2;Q7Z422-3 Q7Z422-4 SZRD1 SUZ domain-containing protein 1 1 S(0.5)KS(0.5)PPKVPIVIQDDSLPAGPPPQIR;S(0.728)KS(0.272)PPKVPIVIQDDSLPAGPPPQIR;S(0.8)KS(0.2)PPKVPIVIQDDSLPAGPPPQIR 107.92 1.4870999999999999e-07 132326000.0 529855.0 556991.0 460398.0 564202.0 577467.0 496143.0 604666.0 519860.0 477207.0 416714.0 True False 619548.9863867239 612285.3854547198 471375.63438913785 532591.591107564 464316.48673154466 470124.3876701659 547387.6590772602 506214.2258372007 484185.2495880538 492260.94949379005 1.2585783760093683 1.2438227856269226 0.9575726753744547 1.0819293946742017 0.9432324201402088 0.9550308391384936 1.1119867615746464 1.028345283853532 0.9835946769410802 1.0 18.909063771177564 -5.25237553115395 24.75210543844782 1.0109143161464604 1.2512006320428082 0.7777333859336439 0.052044311691510026 251.55632896953853 686960.8239458043 0.013444730788546565 0.034485719298702006 5.592737925336417e-06 5.25237553115395 0.24028631589634775 S(ph)KSPPKVPIVIQDDSLPAGPPPQIR ddPTM_PC-9_Lapatinib_30min_R1 2 SKSPPKVPIVIQDDSLPAGPPPQIR 25 2 Q7Z422-4;Q7Z422-5;Q7Z422;Q7Z422-2;Q7Z422-3 Q7Z422-4 SZRD1 SUZ domain-containing protein 1 1 S(0.641)KS(0.359)PPKVPIVIQDDSLPAGPPPQIR;S(0.5)KS(0.5)PPKVPIVIQDDSLPAGPPPQIR 133.94 1.093e-06 127745000.0 112769.0 113724.0 101622.0 113303.0 123209.0 115674.0 110938.0 135997.0 119194.0 102392.0 True False 111160.8933806979 113460.67906518157 93267.0314322639 121635.68058772785 115962.08885821413 110726.89266926405 116681.82681619722 142315.91710145757 105769.116551536 120090.32077123581 0.925644070786122 0.9447945374491649 0.776640705373179 1.0128683128379334 0.9656239413259151 0.9220301183156262 0.9716172466427869 1.185074002529813 0.8807463904857015 1.0 16.87376034955966 -6.721901599487339 0.9351361194135004 1.0208807734801286 0.9019453517326474 0.16960472315344322 0.09018833867968891 0.9075831443807346 1.720890327131356 0.052862843907687515 0.05069398284966861 1.8971357170940363e-07 6.721901599487339 -0.11893542174748117 S(ph)KSPRDPDANWDSPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKSPRDPDANWDSPSR 16 2 Q9UHB7;Q9UHB7-2;Q9UHB7-3 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 S(0.5)KS(0.5)PRDPDANWDSPSR 44.733999999999995 0.041493 4647100.0 5596.6 9225.7 13465.0 20018.0 19378.0 16655.0 17650.0 17665.0 16569.0 10492.0 True False 6543.993842111411 10141.566525472783 13786.056666296867 18896.456359231644 15581.020006136921 15781.582480548175 15978.06422506584 17201.312467614625 16811.290279531615 12394.116545373701 0.5279919563572331 0.8182565081057175 1.1123065218749075 1.5246311659288894 1.2571303447967643 1.2733124158364397 1.2891652395369724 1.38786111980166 1.3563927866893177 1.0 13.597367819103782 -5.167697857753853 1.996413545777928 1.3115023864548383 0.5321467271792518 0.7879927474293862 0.1307382078867349 0.16081725686312667 1.1014266019010137 0.034736483249839294 0.17011002086203014 6.796763245843414e-06 5.167697857753853 -0.7793556592755865 S(ph)KSPVGNPQLIQFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SKSPVGNPQLIQFSR 15 1 G8JLP4;Q9Y4F3-3;Q9Y4F3-4;Q9Y4F3-5;Q9Y4F3 G8JLP4 KIAA0430 Meiosis arrest female protein 1 1 S(0.97)KS(0.03)PVGNPQLIQFSR;S(0.5)KS(0.5)PVGNPQLIQFSR 87.824 0.0023787 49136000.0 38344.0 31796.7 46719.0 54497.0 55679.0 48454.0 56929.0 41724.0 47948.0 42007.0 True False 44834.881871479076 34953.26623893044 47832.95814279417 51443.70977165785 44769.09964504585 45912.98694160797 51536.27298973223 40628.789210232266 48649.14879129596 49622.53657277096 0.9035185415346345 0.7043829004523342 0.9639361759076465 1.0367005261050322 0.9021928893012635 0.9252446592341572 1.0385658724671358 0.8187567991541616 0.9803841591199689 1.0 15.598707863417921 -5.285693536798867 24.711098684173617 0.9542430123779676 0.8039507164801023 0.3934269033859188 0.07649493274550072 564.3001324334253 574930.5183186462 0.019173392396367724 0.03994386914471681 5.179722140467233e-06 5.285693536798867 -0.1502922958978653 S(ph)KSQSSGSSATHPISVPGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SKSQSSGSSATHPISVPGAR 20 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 S(0.565)KS(0.426)QS(0.005)S(0.002)GS(0.001)S(0.002)ATHPISVPGAR;S(0.845)KS(0.142)QS(0.007)S(0.003)GS(0.002)S(0.002)ATHPISVPGAR 83.221 0.00043953 29301000.0 40500.0 32471.0 58603.0 64576.0 78595.0 73900.0 81874.0 53114.0 67129.0 47339.0 True False 47355.85008853805 35694.50628663699 60000.31777311512 60958.016078216766 63194.87394892828 70024.55390648513 74118.30200357176 51719.81377893483 68110.63462940916 55921.18596468222 0.8468320060029892 0.6383002375732936 1.072944300770179 1.0900701590398247 1.1300703455903074 1.2522008018697974 1.3254064756491784 0.9248697588709792 1.2179755034599116 1.0 15.77110733695848 -5.370366600434671 4.690074498808832 1.1396425985170238 0.7447783117772229 0.621460813155795 0.12031732483662584 0.13133609234439708 4.519724091081735 0.031780486482824125 0.06940183283066005 4.262195827262222e-06 5.370366600434671 -0.3948642867398009 S(ph)KSTAALSGEAASCSPIIMPYK ddPTM_PC-9_AZD4547_30min_R2 4 SKSTAALSGEAASCSPIIMPYK 22 1 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 S(0.429)KS(0.429)T(0.142)AALSGEAASCSPIIMPYK;S(0.421)KS(0.421)T(0.15)AALS(0.007)GEAASCSPIIMPYK;S(0.418)KS(0.418)T(0.163)AALS(0.001)GEAASCSPIIMPYK;S(0.421)KS(0.421)T(0.157)AALSGEAASCSPIIMPYK 116.08 7.036700000000001e-07 54729000.0 174163.0 185500.0 348200.0 442511.0 313195.0 302445.0 340455.0 287831.0 240149.0 290537.0 True False 229543.21118455628 245459.24734978945 343582.6404901617 340496.9256767978 269713.2803892204 283533.066338594 370754.8354512735 243353.33264838485 252842.78586609973 280365.3880625801 0.8187287766538435 0.8754976819570921 1.2254816575770435 1.2144756099522378 0.962006338417986 1.0112983927791646 1.3223987383511038 0.8679863599784514 0.9018330957802214 1.0 18.096948729803096 -10.614922311704154 14.663891252309439 0.9999957908775461 1.031713668628074 0.0 0.16557876053114662 0.0 0.0 0.16756770057694978 0.04064113699533162 2.4270442154163306e-11 10.614922311704154 0.03171787775052781 S(ph)KSTAALSGEAASCSPIIMPYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SKSTAALSGEAASCSPIIMPYK 22 1 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 S(0.405)KS(0.405)T(0.155)AALS(0.032)GEAAS(0.003)CSPIIMPYK;S(0.422)KS(0.422)T(0.156)AALS(0.001)GEAASCSPIIMPYK 107.36 4.6906e-05 16611000.0 42110.0 39474.0 36018.0 51828.0 50669.0 50695.0 57376.0 52276.0 47457.0 39751.0 True False 49238.391289588624 43392.717845422296 36876.80571902565 48924.24518864308 40740.77318045993 48036.46495655296 51940.92991373249 50903.81039100042 48150.96884517667 46957.54163125712 1.0485725951380143 0.92408410530031 0.7853223239114107 1.0418825919983177 0.8676087325947444 1.0229765717670718 1.1061254083871843 1.0840390834497282 1.0254150275432041 1.0 15.519069260543581 -6.938342697180784 6.412528997096815 1.0614879020311514 0.9312451465045486 0.35918697274690314 0.07682647258665656 0.21198328674311537 16.775943438233003 0.02701025391605843 0.023722566113966746 1.1525434390703993e-07 6.938342697180784 -0.1302427555266028 S(ph)KSTAALSGEAASCSPIIMPYK ddPTM_PC-9_Lapatinib_30min_R1 2 SKSTAALSGEAASCSPIIMPYK 22 1 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 S(0.422)KS(0.422)T(0.153)AALS(0.002)GEAASCSPIIMPYK;S(0.397)KS(0.397)T(0.194)AALS(0.012)GEAASCSPIIMPYK 87.485 0.00010287 26767200.0 145343.0 165412.0 145864.0 100720.0 112404.0 111676.0 121309.0 117732.0 88020.0 87183.0 True False 143270.38216735795 165028.9986768833 133871.6249713227 108127.28479207042 105792.61771476682 106899.87780947103 127589.78645050427 123202.25852179684 78106.26070830898 102252.46538595475 1.4011435482418926 1.613936622984852 1.3092263787090173 1.0574540612193652 1.0346216818875678 1.0454503703746847 1.2477917864269883 1.2048830124219159 0.7638569927237915 1.0 16.641776102515443 -5.575197327628232 3.2914252554217076 1.0664063261001295 1.5051124412040935 0.6629847923853621 0.13205895762158987 0.14306800672191383 3.1526091963916527 0.03704061119366354 0.07331886137945809 2.6595163976420194e-06 5.575197327628232 0.43870611510396396 S(ph)KSYDEGLDDYREDAK ddPTM_PC-9_Lapatinib_30min_R1 1 SKSYDEGLDDYREDAK 16 2 Q5T5U3;E7ESW5;A0A1B0GV73;Q5T5U3-3 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 S(0.463)KS(0.463)Y(0.074)DEGLDDYREDAK 51.643 0.027655000000000002 18216000.0 330500.0 242410.0 250270.0 257750.0 307280.0 285810.0 285970.0 330310.0 309820.0 360820.0 True False 325787.0093937223 241848.7145386255 229693.76667013706 276705.79482879414 289206.3945357239 273586.5725556508 300776.12733804324 345657.40845594025 274924.8090507644 423187.25623757043 0.7698412572490859 0.5714933778697144 0.542770991528135 0.6538613598360722 0.6834005284255728 0.6464905748533782 0.7107400397926738 0.8167954099777849 0.6496528546134341 1.0 18.690936657560577 -10.345598932925776 0.2670447801524439 1.1856153795542967 0.6090312280709814 0.6519142954988588 0.07403553963784994 7.818746508137081 0.5510322377271352 1.2460487841300847 0.10964105833060626 4.5123322203617804e-11 10.345598932925776 -0.5765841514833153 S(ph)KSYNTPLLNPVQEHEAEGAAAGGTSIR ddPTM_PC-9_AZD4547_30min_R2 1 SKSYNTPLLNPVQEHEAEGAAAGGTSIR 28 1 P85299;P85299-5;P85299-2;P85299-4;P85299-3 P85299 PRR5 Proline-rich protein 5 1 S(0.255)KS(0.255)Y(0.236)NT(0.255)PLLNPVQEHEAEGAAAGGTSIR 43.93600000000001 0.016401 34022000.0 20506.0 18896.0 18451.0 32912.0 24989.0 29071.0 14748.0 27556.0 18231.0 17694.0 True False 27026.48144870324 25003.762468580153 18206.327684330776 25324.646885331145 21519.70869153791 27253.185774369747 16060.543429338299 23297.853373885653 19194.65344067583 17074.538445634444 1.5828528270181894 1.4643887767855315 1.0662852025136704 1.4831819299810156 1.260339116050308 1.5961301596025128 0.9406136207122249 1.3644792477446068 1.1241682170087268 1.0 14.059558960044658 -1.5228825977914893 0.05626554873789534 0.4859470521988551 2.899994325190874 0.3353986165981664 0.18897265868592278 476.72845697564003 2.0197999346430127 18.599227504327192 96.15860134924422 0.02999973387913789 1.5228825977914893 2.4140472729920193 S(ph)KTFSPGPQSQYVCR ddPTM_PC-9_AZD4547_30min_R2 1 SKTFSPGPQSQYVCR 15 1 H0YBE8;H3BLZ3;Q8IX03;Q8IX03-2;H0YAU4 H0YBE8 WWC1 Protein KIBRA 1 S(0.799)KT(0.201)FS(0.001)PGPQSQYVCR 105.99 0.00046679 33382000.0 35605.0 17575.0 35690.0 38571.0 26849.0 24513.0 30945.0 34666.0 30508.0 39297.0 True False 46926.64936999316 23255.775052143108 35216.727280568266 29679.051866009584 23121.479797474945 22980.198234911968 33699.04505159167 29309.16624543185 32120.590596683596 37921.22399107591 1.2374771811436391 0.6132654119396553 0.9286811862627615 0.78265015583342 0.6097239847246538 0.6059983253789475 0.8886592125697773 0.7728961030458628 0.8470346475167208 1.0 15.210717910699037 -4.748950020509502 24.928617168254817 0.7729792583492775 1.2374782994056672 0.5138974011121723 0.13220612847765562 460.629831899208 919354.3709731281 0.03237821685551008 0.5570931765912811 1.7825838990177282e-05 4.748950020509502 0.4644990410563897 S(ph)KTPPPPPQTAQTK ddPTM_PC-9_AZD4547_30min_R2 3 SKTPPPPPQTAQTK 14 1 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 S(0.5)KT(0.5)PPPPPQTAQTK;S(0.5)KT(0.5)PPPPPQTAQTK;S(0.5)KT(0.5)PPPPPQTAQTK 99.663 0.0010142999999999999 50665000.0 112613.0 114499.0 139029.0 154413.0 146648.0 162786.0 138543.0 156948.0 140445.0 145232.0 True False 148421.59150408758 151508.56260001892 137185.38462006516 118815.46850706857 126288.456528739 152606.96568630438 150873.0586066461 132695.29290624915 147868.63597584981 140147.4718851806 1.059038664826475 1.0810652562048797 0.9788644973379027 0.8477888820171596 0.9011111997239882 1.088902736763825 1.0765307185152275 0.9468261619086726 1.0550931385832987 1.0 17.096586194321958 -6.7707342521746465 24.998788997810575 1.032838429820199 0.9728513356491092 0.1424051449421455 0.07347510882846427 478.0459599480643 1285709.0939481978 0.02905769212654685 0.025973304122262588 1.6953748948461475e-07 6.7707342521746465 -0.05998709417108972 S(ph)KTPPPPPQTAQTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKTPPPPPQTAQTK 14 1 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 S(0.5)KT(0.5)PPPPPQTAQTK 61.409 0.024606 15512000.0 24395.0 26000.0 21052.0 27077.0 31889.0 19832.0 23949.0 24728.0 24945.0 19860.0 True False 28524.591676787324 28581.108171986132 21553.9595201546 25559.96347481844 25640.57936710189 18791.97500775932 21680.377344255063 24078.91620148172 25309.77343369643 23460.460788326516 1.2158581169463059 1.218267127396217 0.9187355574396665 1.0894911104020855 1.092927355453315 0.8010062196693875 0.9241241056545151 1.0263616055428433 1.0788267827326776 1.0 14.517943729254535 -5.2499116764409965 24.17450849498198 0.9902974512675106 1.2170626931584898 0.5207961030226458 0.08656707310809011 393.1349240840266 824428.2854674667 0.023518327783087874 0.06099216304648306 5.624557015874239e-06 5.2499116764409965 0.22676524189097924 S(ph)KTPPPPPQTAQTK ddPTM_PC-9_Lapatinib_30min_R1 2 SKTPPPPPQTAQTK 14 1 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 S(0.762)KT(0.238)PPPPPQTAQTK;S(0.5)KT(0.5)PPPPPQTAQTK 103.3 0.00058908 32275000.0 81097.0 86692.0 88164.0 86874.0 107010.0 96210.0 83754.0 88330.0 101821.0 86544.0 True False 79940.5419086316 86491.27000034071 80915.49624288175 93263.00376316864 100715.88218975479 92095.32257646395 88090.37230853068 92434.13426451871 90352.84675733616 101503.01508736846 0.787568150954166 0.852105426877158 0.7971733270507674 0.9188200338964586 0.9922452264404545 0.9073161274785102 0.867859661436728 0.910654074511543 0.890149387972024 1.0 16.631163056891488 -5.769038994481397 24.853801293013742 0.9224670445512586 0.8162646119119218 0.6060780236051616 0.04214460585857076 112.25256014419328 367112.1051336526 0.012017781321213216 0.018219259606175202 1.7020056816579978e-06 5.769038994481397 -0.10620243263933682 S(ph)LAADDEGGPELEPDYGTATR ddPTM_PC-9_AZD4547_30min_R2 1 SLAADDEGGPELEPDYGTATR 21 0 C9JJX6;E9PDC3;O00192-2;O00192 C9JJX6 ARVCF Armadillo repeat protein deleted in velo-cardio-facial syndrome 1 S(1)LAADDEGGPELEPDYGTATR 177.0 2.6658999999999997e-41 0.0 2837.5 2940.0 1070.0 3144.3 3767.1 2450.5 2584.0 5649.9 3850.2 4077.0 True False 3739.7659763335346 3890.297505166473 1055.8111008744204 2419.4302139507404 3244.1031898792476 2297.2698476176633 2813.9709941287056 4776.8377767860575 4053.7137116609115 3934.2654709422177 0.9505626918048053 0.9888243520676263 0.2683629533066471 0.614963639800166 0.8245765858556354 0.5839132779892177 0.7152468522808623 1.2141625449698117 1.030361001717072 1.0 11.941878593750312 -7.747900128905493 23.931001615176605 1.0916962574130276 0.6969226197068956 0.42589957195005634 0.19912087591951882 127.33576741250668 225070.86852648878 0.0992500237002176 0.056842557256236624 1.7868984458005393e-08 7.747900128905493 -0.39477363770613194 S(ph)LAADDEGGPELEPDYGTATR ddPTM_PC-9_Lapatinib_30min_R1 1 SLAADDEGGPELEPDYGTATR 21 0 C9JJX6;E9PDC3;O00192-2;O00192 C9JJX6 ARVCF Armadillo repeat protein deleted in velo-cardio-facial syndrome 1 S(1)LAADDEGGPELEPDYGTATR 218.22 2.8170999999999993e-93 0.0 1744.6 3631.1 2754.1 2914.3 2202.1 3107.3 2049.8 1070.8 3354.6 1080.1 True False 1719.7216840795438 3622.6924110441187 2527.668529133438 3128.627343819806 2072.5768074951766 2974.4080224700856 2155.928614251572 1120.5532771475887 2976.76962249595 1266.7938458572157 1.357538710583047 2.859733194072087 1.9953274460557644 2.469720984240117 1.6360805779670509 2.3479811116838505 1.7018780295642306 0.8845585102991491 2.349845345579198 1.0 10.30696604847897 -7.487378432980051 6.824044903481989 1.4293674671274903 2.1276286058732925 0.2581918584520996 0.5369260258480127 0.26798987300754024 39.844347524369404 0.2163707532639332 0.14089886509253374 3.255528989941838e-08 7.487378432980051 0.6982611387458022 S(ph)LAEPLR ddPTM_PC-9_AZD4547_30min_R2 1 SLAEPLR 7 0 B8ZZJ5;Q02080-2;C9J4J4 B8ZZJ5 MEF2B 1 S(1)LAEPLR 86.833 0.020484 0.0 3445.4 4565.6 4425.7 6881.3 4547.5 5381.2 4715.3 7470.3 5641.7 4604.9 True False 4540.965531228042 6041.3409148258625 4367.012326298992 5294.922600025195 3916.158120563796 5044.712713323883 5134.952565253518 6315.936785416533 5939.908744241177 4443.683852622472 1.0218921241546377 1.3595343672481384 0.9827459538377754 1.1915615006905493 0.8812863944523521 1.135254640211794 1.1555620821726749 1.4213290132440761 1.3367082225563138 1.0 12.117540464017758 -7.557406532055452 10.787314686354346 1.2853148590455716 1.1009226087118418 0.15731055619284062 0.15724895874318956 0.8216725055453376 250.74079877720257 0.07120511105563201 0.04115504361392875 2.7707252846656533e-08 7.557406532055452 -0.18439225033372986 S(ph)LASIEAK ddPTM_PC-9_Lapatinib_30min_R1 2 SLASIEAK 8 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 S(0.821)LAS(0.179)IEAK;S(0.677)LAS(0.323)IEAK 96.665 0.0060501999999999995 173336000.0 1138410.0 645780.0 842880.0 844720.0 809530.0 814810.0 771440.0 835750.0 1099810.0 1281160.0 True False 1122176.0646411758 644284.7360866062 773581.660010892 906843.5267033126 761915.0369972162 779962.4757148818 811381.3885150907 874581.9960553774 975937.816287269 1502606.7989616098 0.7468195042220399 0.42877799869656186 0.5148264073778201 0.603513525514456 0.5070621519373828 0.5190729046706577 0.5399825084485197 0.5820431510490737 0.6494964730371909 1.0 20.51903610459111 -8.897591733802365 1.2918683416164067 0.999964473863051 0.5443778340513711 0.7441310554390554 0.07817759040883475 0.6415352590302654 1.6384724284791268 0.07090763759807155 0.0212208634144594 1.265925844226772e-09 8.897591733802365 -0.4555866398116799 S(ph)LDDLSAPPHHR ddPTM_PC-9_AZD4547_30min_R2 2 SLDDLSAPPHHR 12 0 A6NKD9 A6NKD9 CCDC85C Coiled-coil domain-containing protein 85C 1 S(0.996)LDDLS(0.004)APPHHR;S(0.976)LDDLS(0.024)APPHHR 95.98100000000001 0.0025085 11061200.0 26939.8 20133.3 45514.0 60794.0 53190.0 52377.0 38182.0 53724.0 36335.0 46616.0 True False 35506.09601734984 26640.995496859898 44910.454621680714 46778.88255793696 45805.48662623161 49101.85791008786 41580.124031664964 45422.190254704336 38255.593920627325 44983.98802880612 0.7893052077688848 0.5922328513825846 0.9983653426397341 1.039900742637168 1.018262022408939 1.091540791773393 0.9243316534105104 1.0097412934046135 0.850426909595695 1.0 15.457123947609087 -5.272781264908965 24.934513719692305 0.9957672547546145 0.6907690329068669 0.7155584161608033 0.07582342512241937 301.636466893175 663131.8021364538 0.019284900919385548 0.04072235129436957 5.336035805498033e-06 5.272781264908965 -0.3049982218477476 S(ph)LDDLSAPPHHR ddPTM_PC-9_Lapatinib_30min_R1 2 SLDDLSAPPHHR 12 0 A6NKD9 A6NKD9 CCDC85C Coiled-coil domain-containing protein 85C 1 S(0.998)LDDLS(0.002)APPHHR;S(0.679)LDDLS(0.321)APPHHR 113.53 0.00069207 0.0 69019.0 52360.0 69412.0 54729.0 65210.0 61037.0 56433.0 56775.0 64732.0 51887.0 True False 68034.77640346547 52238.7636369888 63705.21329806838 58753.953230592015 61374.47600779276 58426.58979419642 59354.82461121035 59412.97376732754 57441.200501820764 60855.59881491839 1.1179706999578014 0.8584052191461269 1.0468258391773713 0.9654650414217735 1.0085263673840832 0.9600856935430153 0.9753387653242493 0.9762942921327856 0.9438934398873977 1.0 15.893102378904887 -6.7716423800713 24.789575866780837 0.9699043537666098 0.9923486456659842 0.04240487003344884 0.0627877701087274 845.757774411247 2054870.2005040487 0.020432908823488458 0.01822104893005783 1.6918334990402724e-07 6.7716423800713 0.02244429189937447 S(ph)LDEADSENKEEVSPLGSK ddPTM_PC-9_AZD4547_30min_R2 1 SLDEADSENKEEVSPLGSK 19 1 Q6ZV73-2;Q6ZV73;F8VQX5 Q6ZV73-2 FGD6 FYVE, RhoGEF and PH domain-containing protein 6 1 S(1)LDEADSENKEEVSPLGSK 82.406 0.005121 0.0 10665.0 13120.0 11786.0 12727.0 14848.0 14779.0 11218.0 15293.0 13445.0 13118.0 True False 14056.248154219264 17360.78342441636 11629.709939164402 9792.986780189889 12786.611495136063 13854.866793691683 12216.380267854427 12929.818248179461 14155.675251488481 12658.742812808441 1.1103984307191066 1.3714460970682076 0.9187097100509194 0.7736144832866889 1.0101012149641149 1.0944899504295935 0.9650547805974523 1.0214140882218365 1.1182528518681496 1.0 13.627846511978555 -5.270395225971726 24.986162587575265 0.9846280587824068 1.2409222691185875 0.47023774335505086 0.1074670424532486 498.5691430734456 1390973.8410248857 0.02930272639168373 0.06246028570333837 5.365432974966864e-06 5.270395225971726 0.2562942103361807 S(ph)LDGAPIGVMDQSLMK ddPTM_PC-9_AZD4547_30min_R2 2 SLDGAPIGVMDQSLMK 16 0 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 S(1)LDGAPIGVMDQSLMK;S(0.999)LDGAPIGVMDQS(0.001)LMK 111.43 0.00027461 11338500.0 61237.0 59909.0 77729.0 92552.0 81651.0 71067.0 74668.0 97564.0 70219.0 81080.0 True False 80709.09219127291 79273.41266565255 76698.26267277365 71215.56631414579 70315.16804885212 66623.16925551694 81313.30734891731 82487.72559768391 73930.63298507032 78241.41387883131 1.0315392857836538 1.0131899301873486 0.9802770536784079 0.9102029575338949 0.8986950077071181 0.8515077367938803 1.0392617326016538 1.0542719195415953 0.944904102826709 1.0 16.255644820616027 -9.863597352004637 10.90217626595951 1.0000082613358159 0.96820457405902 0.01999002754382173 0.06402675352343469 0.0 0.0 0.06849374620249715 0.01661217354630261 1.368997477774143e-10 9.863597352004637 -0.03180368727679583 S(ph)LDGAPIGVMDQSLMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLDGAPIGVMDQSLMK 16 0 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 S(0.98)LDGAPIGVMDQS(0.02)LMK 58.658 0.031464 4189800.0 25728.0 26112.0 24717.0 29503.0 34807.0 27138.0 25930.0 27687.0 26384.0 21050.0 True False 30083.24224883721 28704.226791803903 25306.347019744495 27850.042560016544 27986.81821414015 25714.835506281353 23473.722683057083 26960.245586801375 26769.816086375922 24866.19836829168 1.2098046433667191 1.154347213300056 1.0177006812595075 1.1199959940611484 1.1254964590738465 1.0341281415607066 0.944001263698989 1.0842126000723913 1.07655443304561 1.0 14.601898339679918 -6.777434620906501 7.357987470976744 1.027502665347534 1.1208804122259486 0.4180456005606761 0.05751529720022655 0.1787256514403017 46.169409023451216 0.02123333560872729 0.019364484730856037 1.6694191041933116e-07 6.777434620906501 0.09337774687841449 S(ph)LDGAPIGVMDQSLMK ddPTM_PC-9_Lapatinib_30min_R1 2 SLDGAPIGVMDQSLMK 16 0 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 S(1)LDGAPIGVMDQSLMK;S(0.994)LDGAPIGVMDQS(0.006)LMK 87.647 0.0025050000000000003 6795300.0 31443.0 34466.0 34238.0 25930.0 34137.0 31383.0 30679.0 32181.0 36500.0 28939.0 True False 30994.61705406 34386.196094584724 31423.083802501995 27836.97869994428 32129.128775924273 30040.82224734612 32267.40850650014 33676.24674251639 32388.98563796048 33941.06759120634 0.9131892204265925 1.013114746676198 0.9258130646026963 0.8201562495092658 0.9466151496144596 0.8850877234966317 0.9506892621981101 0.9921976276091399 0.954271268896445 1.0 15.050744324050408 -7.5186036795946265 5.9550870714209925 0.9787792166680271 0.9187812733433214 0.27945809401109223 0.04674821507030705 0.23425889933265712 33.61279307817176 0.022471157821952952 0.013718680082875493 3.029676933373285e-08 7.5186036795946265 -0.05999794332470576 S(ph)LDGLSEACGGAGSSGSAESGAGGGR ddPTM_PC-9_Lapatinib_30min_R1 1 SLDGLSEACGGAGSSGSAESGAGGGR 26 0 Q96GS4 Q96GS4 C17orf59 Uncharacterized protein C17orf59 1 S(0.999)LDGLS(0.001)EACGGAGSSGSAESGAGGGR 132.66 4.3687e-10 2587700.0 2857.5 4339.4 5985.1 4967.9 6153.8 6262.5 2254.1 5037.6 6083.1 2565.5 True False 2816.7515259986794 4329.352385911939 5493.028181154116 5333.255938428583 5791.845582836299 5994.6674736005225 2370.806268603993 5271.665286662958 5397.9572201171895 3008.94325668613 0.9361265021331379 1.438828192021151 1.8255672216310947 1.7724681004128713 1.9248769713308225 1.9922833241470597 0.787919899564692 1.7519989035847936 1.7939710920511596 1.0 11.55504118492941 -10.708706428618605 4.543603969827895 0.9998951439443685 1.5931195068611022 0.16520241736072572 0.3905084729235833 0.00048157904437567543 8.629354692299792e-05 0.388324368331131 0.09416382417669344 1.9556609832576265e-11 10.708706428618605 0.5932243629167336 S(ph)LDGSGSEPAVCEMCGIVGTR ddPTM_PC-9_AZD4547_30min_R2 2 SLDGSGSEPAVCEMCGIVGTR 21 0 H7C228;Q969R5-2;Q969R5-3;Q969R5 H7C228 L3MBTL2 Lethal(3)malignant brain tumor-like protein 2 1 S(1)LDGSGSEPAVCEMCGIVGTR;S(0.623)LDGS(0.013)GS(0.358)EPAVCEMCGIVGT(0.006)R 213.64 6.9522e-32 13660900.0 28470.0 26013.0 46190.0 54218.0 38079.0 39023.0 33752.0 45000.0 31147.0 38779.0 True False 37522.8677872126 34421.19353805968 45577.49041999013 41718.877759749776 32792.38814138509 36582.88564112797 36755.86261371211 38046.283997127815 32793.366832139254 37421.359013408946 1.0027125891864932 0.919827458049446 1.2179539071164853 1.1148413328548792 0.8763013692163028 0.9775937220243516 0.9822161349228826 1.016699687028869 0.876327522482244 1.0 15.19157433273807 -6.250784131539473 24.979608349557328 0.9581962408054375 1.0645562290676411 0.2877985714191825 0.0838827651984008 1041.1881642954036 2440907.066284776 0.02613112805184644 0.033374854826052666 5.613269173332152e-07 6.250784131539473 0.10635998826220361 S(ph)LDGSGSEPAVCEMCGIVGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLDGSGSEPAVCEMCGIVGTR 21 0 H7C228;Q969R5-2;Q969R5-3;Q969R5 H7C228 L3MBTL2 Lethal(3)malignant brain tumor-like protein 2 1 S(0.989)LDGS(0.01)GS(0.001)EPAVCEMCGIVGTR;S(0.712)LDGSGS(0.288)EPAVCEMCGIVGTR 171.25 4.7164e-32 4330000.0 14497.7 14234.8 15358.099999999999 17139.300000000003 19081.4 15824.4 18354.1 18072.1 15465.6 13743.7 True False 16951.874267372797 15647.936869484152 15724.295349918602 16179.040587360327 15342.536646976008 14994.540606735905 16615.466775823283 17597.726523972742 15691.755141959344 16235.32401493066 1.0441352603608753 0.9638204236080338 0.9685236546839413 0.9965332735263815 0.9450095749777702 0.9235750757389455 1.0234145472269618 1.0839159420402797 0.9665193702034263 1.0 13.986848556909454 -7.415432514760883 12.400487607801397 1.0258503781533088 0.9726819630951549 0.21841063969547692 0.04062953022901257 0.9634286306023117 106.45087737447001 0.016858942558071233 0.011362443690768921 3.842089569644787e-08 7.415432514760883 -0.05316841505815395 S(ph)LDGSGSEPAVCEMCGIVGTR ddPTM_PC-9_Lapatinib_30min_R1 2 SLDGSGSEPAVCEMCGIVGTR 21 0 H7C228;Q969R5-2;Q969R5-3;Q969R5 H7C228 L3MBTL2 Lethal(3)malignant brain tumor-like protein 2 1 S(0.502)LDGS(0.025)GS(0.471)EPAVCEMCGIVGT(0.002)R;S(0.932)LDGS(0.057)GS(0.011)EPAVCEMCGIVGTR 100.27 0.00018018 6189800.0 15468.4 18316.4 23712.2 20211.1 25377.3 26151.8 19102.9 19106.1 24699.5 18339.3 True False 15247.817779442856 18273.98950115626 21762.674447738977 21697.49171625312 23884.657107691444 25033.34847682332 20091.95469079245 19993.839156247235 21917.582212734374 21509.223569418788 0.7088967079742374 0.8495885238339196 1.011783357846563 1.0087529029686597 1.1104379026330817 1.1638424974304993 0.9341087848172552 0.9295472285049804 1.0189852805238484 1.0 14.392667827473312 -5.001730295146655 1.9249750042815879 1.0270637459095344 0.6781651329782972 0.6972693449827028 0.06723241735823739 0.3113397022646722 1.7128930283965902 0.020846256708277524 0.16704446495016634 9.960237743917671e-06 5.001730295146655 -0.34889861293123725 S(ph)LDNNYSTPNER ddPTM_PC-9_Lapatinib_30min_R1 2 SLDNNYSTPNER 12 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-25;O60716-27;O60716-29;O60716-26;H0YC95 O60716 CTNND1 Catenin delta-1 1 S(1)LDNNYSTPNER;S(1)LDNNYSTPNER 175.29 0.0010566 19994600.0 24965.8 21240.9 22133.5 14368.6 17797.1 15077.4 14219.400000000001 9011.5 17340.7 12902.7 True False 24609.783113833 21191.71800108701 20313.769067780748 15425.314776244479 16750.30956844485 14432.574749136053 14955.610955941462 9430.207188098151 15387.607760333736 15132.914503232936 1.626242129933098 1.400372545325601 1.3423566929847515 1.0193221387029627 1.1068792838858885 0.9537207618567285 0.988283582303092 0.6231586906860221 1.0168304167083206 1.0 13.885402247767137 -5.2061843929984075 0.6003809134343301 0.8749715641306992 1.881254920956704 0.8013924872124565 0.11875028204799634 0.966416752709434 0.37423117106597276 0.06367014498246115 0.6284317439486744 6.2203612464243525e-06 5.2061843929984075 1.0062833568260048 S(ph)LDQPFLSK ddPTM_PC-9_AZD4547_30min_R2 2 SLDQPFLSK 9 0 G5E9Y3;Q8WWN8;Q8WWN8-2 G5E9Y3 ARAP3 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 1 S(1)LDQPFLSK;S(1)LDQPFLSK 125.28 0.0014315 14179100.0 65425.0 75915.0 85715.0 108533.0 127828.0 103545.0 97592.0 136238.0 97351.0 92046.0 True False 86228.7890754613 100453.03915126296 84578.3630948139 83512.39366813462 110081.28867189206 97070.31478129803 106277.49893924489 115185.54753779355 102496.7751139946 88823.49755662186 0.9707880397356958 1.13092866093488 0.9522070783229197 0.9402060937185952 1.239326210969334 1.0928449954294934 1.1965020727932574 1.2967913976182575 1.1539376171114688 1.0 16.43865376022452 -6.261715919299488 24.99991819422562 1.1762172686142398 1.0046803809964124 0.43984721469891497 0.09023851171958329 22.811451771808212 2062220.1541259775 0.027064361455012106 0.03263186730721943 5.473738940202639e-07 6.261715919299488 -0.17153688761782737 S(ph)LDQPFLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLDQPFLSK 9 0 G5E9Y3;Q8WWN8;Q8WWN8-2 G5E9Y3 ARAP3 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 1 S(1)LDQPFLSK;S(1)LDQPFLSK 104.79 0.0037584000000000003 5917000.0 61605.0 64791.0 72025.0 75583.0 77907.0 55632.0 52848.0 62912.0 42843.0 41285.0 True False 72033.50974578733 71223.02229119823 73742.34915633341 71348.32955339206 62641.68261007888 52714.559985461165 47841.85485361361 61260.62666077395 43469.49782400708 48769.64368811983 1.4770152967784451 1.460396609552183 1.5120542940176713 1.462965979609409 1.2844400301685666 1.0808887660235726 0.9809760997960247 1.2561220880048565 0.8913228503778498 1.0 15.573695811606225 -6.550359022225384 2.1176953963246032 1.0481981556896744 1.4829836766344822 0.8470724860675867 0.0876439946563097 0.11602913206697672 1.0512587463357257 0.03097714240939375 0.032818410245894866 2.816053995423346e-07 6.550359022225384 0.4347855209448077 S(ph)LDQPFLSK ddPTM_PC-9_Lapatinib_30min_R1 2 SLDQPFLSK 9 0 G5E9Y3;Q8WWN8;Q8WWN8-2 G5E9Y3 ARAP3 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 1 S(1)LDQPFLSK;S(1)LDQPFLSK 109.16 0.0023874 12111700.0 96836.0 92114.0 99070.0 97876.0 91189.0 76504.0 91025.0 79722.0 110401.0 144431.0 True False 95455.10088245237 91900.71569246751 90924.84702125932 105074.12754476482 85825.44230447183 73232.10225953434 95737.82911125448 83426.17515946951 97966.47680593075 169395.70590778982 0.5635036636313151 0.5425209287329483 0.5367600467437709 0.6202880231330167 0.5066565403445984 0.4323138055187661 0.5651727037482825 0.4924928569610989 0.5783291629556335 1.0 17.370037778008594 -8.67057676540984 6.547698028249957 0.9999998306459351 0.5328634802380262 0.8976303758678918 0.04707713744818549 1.8642507438119738 82.69511350755123 0.04693154220224622 0.012150231975596395 2.1351246504311656e-09 8.67057676540984 -0.4671363504079089 S(ph)LDTPQSLASLSSR ddPTM_PC-9_Lapatinib_30min_R1 1 SLDTPQSLASLSSR 14 0 Q9ULE0;Q9ULE0-2 Q9ULE0 WWC3 Protein WWC3 1 S(1)LDTPQSLASLSSR 85.287 0.0069535 3794200.0 10136.0 7797.3 7981.3 5721.8 4399.0 5357.5 6337.7 5058.5 10067.0 5457.7 True False 9991.45878128525 7779.245830914682 7325.108322708946 6142.600259365259 4140.259468766759 5128.372213942482 6665.835095395741 5293.5363769621545 8933.148449790357 6401.056173071875 1.5609078425709764 1.2153066026260808 1.144359325188302 0.9596229267923169 0.6468088010513182 0.8011759427321772 1.0413648802892475 0.8269785850702479 1.3955741378072188 1.0 12.64409425382756 -4.898885882107882 1.2621796327821102 0.9363362086401126 1.7332033955843356 0.48852326574892657 0.18932422395435816 0.99040569038633 1.5952702437806292 0.058808306423476335 0.9759581073693971 1.2621591437289502e-05 4.898885882107882 0.796867186944223 S(ph)LDYLNLDK ddPTM_PC-9_AZD4547_30min_R2 4 SLDYLNLDK 9 0 Q96GV9 Q96GV9 C5orf30 UNC119-binding protein C5orf30 1 S(1)LDYLNLDK;S(1)LDYLNLDK;S(1)LDYLNLDK;S(0.998)LDY(0.002)LNLDK 142.83 0.00063893 18494300.0 43174.8 47117.5 69242.1 89186.5 73244.0 80313.0 76716.0 90318.0 75864.6 79891.0 True False 56903.48830837185 62347.31044206848 68323.90451201556 68625.93034268927 63075.33488346883 75291.01541388196 83543.57538141577 76361.42840116855 79874.64787534955 77094.0404069277 0.7381048912213776 0.8087176403387197 0.8862410654750942 0.8901586942448345 0.8181609700378456 0.9766126540582284 1.0836580225974057 0.990497164217984 1.0360677356348802 1.0 16.23433171948635 -6.862990041803192 4.047713300076323 1.0272528395319054 0.8335900248989511 0.8072223465944524 0.04659503440731505 0.10301918958812369 3.112845251657885 0.017940485512990413 0.0158576479539365 1.3709132002896465e-07 6.862990041803192 -0.19366281463295432 S(ph)LDYLNLDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLDYLNLDK 9 0 Q96GV9 Q96GV9 C5orf30 UNC119-binding protein C5orf30 1 S(0.995)LDY(0.005)LNLDK;S(1)LDYLNLDK 152.96 7.4797e-05 10406100.0 27137.0 26195.0 32585.0 45630.0 52545.0 50613.0 55860.0 52781.0 51777.0 46855.0 True False 31730.758119818714 28795.46648327602 33361.949979300654 43073.499034455985 42249.184447438565 47958.76518090568 50568.536408622 51395.55467609218 52534.14067253961 55349.440596024055 0.5732805567342635 0.520248554875991 0.6027513488853067 0.7782101963565302 0.7633172800390231 0.8664724460530632 0.9136232609414036 0.9285650247345788 0.9491358920132125 1.0 15.756281115645342 -6.067917120196299 0.5697400494776589 0.9761458779252635 0.4660160616383561 0.9551350183711369 0.03450672889853446 0.22682569608545788 0.13921697763519614 0.0246487903688778 0.06456074133058563 8.552299075068181e-07 6.067917120196299 -0.5101298162869075 S(ph)LDYLNLDK ddPTM_PC-9_Lapatinib_30min_R1 3 SLDYLNLDK 9 0 Q96GV9 Q96GV9 C5orf30 UNC119-binding protein C5orf30 1 S(1)LDYLNLDK;S(0.993)LDY(0.007)LNLDK;S(1)LDYLNLDK 134.08 0.0011357000000000001 13200900.0 35484.8 34399.5 36594.4 32395.1 35074.2 40393.9 39535.0 41372.0 38477.3 29588.9 True False 34978.78024488465 34319.85007124899 33585.74969046903 34777.54372088564 33011.204514530335 38666.34705977997 41581.92885375931 43294.2941559115 34143.58129006839 34703.301940269055 1.0079381006766948 0.988950565289722 0.967796947629838 1.0021393290109502 0.9512410251724421 1.1141979263625135 1.1982124618956913 1.2475554698059903 0.9838712566555179 1.0 15.082785318036473 -6.81566432156689 6.619661449853136 1.1310474109849515 0.984161708647188 0.3824926617870378 0.07705084684117926 0.18671445096712533 17.276931938024283 0.026635107211911337 0.023662009198086503 1.528747213470079e-07 6.81566432156689 -0.14688570233776355 S(ph)LEDISSDSSNQAK ddPTM_PC-9_AZD4547_30min_R2 1 SLEDISSDSSNQAK 14 0 A0A0U1RRJ3;A0A0U1RQP0;A0A0U1RR07;Q9HCH5-11;Q9HCH5-7;Q9HCH5-8;A0A0U1RQH1;Q9HCH5-15;Q9HCH5-12;Q9HCH5-14;Q9HCH5-6;Q9HCH5;Q9HCH5-13 A0A0U1RRJ3 SYTL2 Synaptotagmin-like protein 2 1 S(1)LEDISSDSSNQAK 146.59 5.4847e-08 0.0 3886.2 5347.7 8566.2 11517.0 11011.0 12549.0 9588.0 10192.0 8149.2 9930.5 True False 5121.930762018461 7076.239445026787 8452.606590944351 8861.933585876239 9482.312713694986 11764.30904621671 10441.31342558283 8617.060588860597 8579.95007507847 9582.836217608954 0.5344900659584111 0.7384285074207815 0.8820568774213476 0.9247714752331863 0.9895100467511643 1.2276437558850466 1.0895848774287074 0.8992181848027733 0.8953455824813504 1.0 13.226236996103507 -4.930071302218828 0.9877209456616731 1.0209016878767931 0.36014779334504804 0.7373962282739924 0.09148147386992243 0.9024178706885343 0.8306118984735388 0.035193232129948626 0.6035027848168851 1.1747046767668983e-05 4.930071302218828 -0.660753894531745 S(ph)LEDISSDSSNQAK ddPTM_PC-9_Lapatinib_30min_R1 1 SLEDISSDSSNQAK 14 0 A0A0U1RRJ3;A0A0U1RQP0;A0A0U1RR07;Q9HCH5-11;Q9HCH5-7;Q9HCH5-8;A0A0U1RQH1;Q9HCH5-15;Q9HCH5-12;Q9HCH5-14;Q9HCH5-6;Q9HCH5;Q9HCH5-13 A0A0U1RRJ3 SYTL2 Synaptotagmin-like protein 2 1 S(1)LEDISSDSSNQAK 193.98 4.1698e-37 0.0 12650.0 8538.1 8590.6 9978.7 14991.0 14306.0 10770.0 10612.0 12944.0 13616.0 True False 12469.608680274121 8518.330554029304 7884.314028674967 10712.566885967366 14109.258853439973 13694.16572891482 11327.617901985272 11105.07226101066 11486.110413637267 15969.507457820444 0.7808386522383078 0.5334122280557742 0.4937105323692329 0.6708138566115452 0.8835124621536473 0.8575196051027006 0.7093279446410234 0.6953922837220872 0.7192526409455661 1.0 13.963032196423956 -6.027801894057373 7.4132530221288135 0.7918187665244321 0.5932707369896605 0.4129380965237126 0.11230595286028237 0.215879365959089 46.641499730815674 0.03340737567009123 0.04467272174758163 9.379897788220253e-07 6.027801894057373 -0.19854802953477158 S(ph)LEDLRAPK ddPTM_PC-9_Lapatinib_30min_R1 1 SLEDLRAPK 9 1 Q8TEH3;Q8TEH3-7;Q8TEH3-6 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 S(1)LEDLRAPK 84.31 0.006278199999999999 19043000.0 254350.0 161690.0 182570.0 146460.0 155770.0 156830.0 116150.0 133220.0 192580.0 101960.0 True False 250722.9223579221 161315.61673920436 167559.79934057998 157231.15697623717 146607.91485560304 150122.746488586 122163.67867368514 139409.88754352037 170889.61244269676 119583.65014684007 2.09663212362269 1.3489771932962447 1.4011932160862182 1.3148215227012112 1.225986283873917 1.2553785262805253 1.021575094284854 1.1657938804538506 1.4290382693023393 1.0 16.86766062764756 -2.058177102828158 0.9577193224104069 1.2044883736918524 199.99999999996518 0.7979387272609133 0.1310853831327532 169.14399499174718 0.9106082925303599 0.041840030562047034 72865.35027643378 0.008746270345466253 2.058177102828158 198.79551162627334 up S(ph)LEDVTAEYIHK ddPTM_PC-9_AZD4547_30min_R2 2 SLEDVTAEYIHK 12 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 S(1)LEDVTAEYIHK;S(1)LEDVTAEYIHK 193.81 1.7307e-05 4251700.0 14576.6 10901.8 19960.4 21150.0 21143.0 20722.0 17372.0 19799.9 16662.0 17040.1 True False 19211.6555878849 14425.593653681586 19695.712054106323 16274.194264242647 18207.659404745533 19426.25006420455 18918.074345976747 16740.280411438478 17542.719303852824 16443.53128560278 1.1683412312235975 0.8772807618465742 1.197778732075087 0.9897019065784004 1.107284018773227 1.1813916200112868 1.150487326438243 1.018046557073511 1.0668462265895673 1.0 14.005232533870316 -4.470235147197594 23.74193481007123 1.0722577474096713 2.876097980878368 0.0938019138202717 0.09382602959648675 1014.2641863722733 743545.2152801423 0.021928789121247804 59229.17037536469 3.386607398394426e-05 4.470235147197594 1.8038402334686967 S(ph)LEDVTAEYIHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLEDVTAEYIHK 12 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 S(0.994)LEDVT(0.006)AEYIHK 119.87 0.00065154 0.0 6046.4 8251.3 8089.8 9932.9 9737.1 8600.7 8644.8 8055.2 8093.9 6423.1 True False 7069.936098156458 9070.434533058044 8282.691512737352 9376.391815896297 7829.185153357209 8149.664151332967 7825.901961067943 7843.759535189892 8212.257975345583 7587.5571847683805 0.9317802720945524 1.1954354098663613 1.0916150364394508 1.23575896531217 1.0318452912715945 1.0740827321463866 1.0314125838521557 1.033766117893098 1.0823322678649798 1.0 12.88941976916001 S(ph)LEDVTAEYIHK ddPTM_PC-9_Lapatinib_30min_R1 1 SLEDVTAEYIHK 12 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 S(1)LEDVTAEYIHK 109.22 0.0022698 0.0 9410.6 6697.6 10023.0 8413.8 7787.8 7875.1 8326.2 8422.6 8412.0 6362.5 True False 9276.403118307313 6682.092118699317 9198.947629898861 9032.578919614009 7329.736915403901 7538.300330754722 8757.289895590515 8813.944744212999 7464.551977712973 7462.249647501658 1.2431107985529577 0.8954527701892773 1.232731155406821 1.2104364429348853 0.98224225423199 1.0101913882335103 1.1735455538561932 1.1811377480735832 1.0003085303119128 1.0 12.865394910588414 -6.2550696496262885 24.969398561214916 1.0703575560570517 1.133812665703787 0.11626743501165127 0.11339265348117737 1606.9179897984438 6299130.970519541 0.034520224034687165 0.04342034713227904 5.558151117232591e-07 6.2550696496262885 0.06345510964673529 S(ph)LEGGGCPAR ddPTM_PC-9_AZD4547_30min_R2 4 SLEGGGCPAR 10 0 Q9Y613 Q9Y613 FHOD1 FH1/FH2 domain-containing protein 1 1 S(1)LEGGGCPAR;S(1)LEGGGCPAR;S(1)LEGGGCPAR;S(1)LEGGGCPAR 126.03 0.00035989 117134000.0 7178.3 13656.099999999999 19489.3 33364.0 23307.4 22054.3 19836.1 24199.0 21970.9 25362.5 True False 9460.850082084591 18070.167265409473 19230.859147917592 25672.44526866153 20071.56982500905 20675.2411345906 21601.47447238251 20459.60058769993 23132.236919518673 24474.56659474417 0.38655843180962707 0.738324300675869 0.7857487107472356 1.04894381558424 0.8200990913285202 0.8447643415687915 0.8826090704716035 0.8359535401167659 0.9451540982338066 1.0 14.578995691793148 -4.6008748956515 1.4377572902844502 0.8944014239109545 6.34584510937611e-18 0.8089728857952074 0.07572800152894389 0.7586013907683473 1.0442922391587723 0.021179712393701675 1.105026542913614 2.506831275393294e-05 4.6008748956515 -0.8944014239109545 down S(ph)LEGGGCPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLEGGGCPAR 10 0 Q9Y613 Q9Y613 FHOD1 FH1/FH2 domain-containing protein 1 1 S(1)LEGGGCPAR;S(1)LEGGGCPAR;S(1)LEGGGCPAR;S(1)LEGGGCPAR 109.16 0.0019242999999999999 90363000.0 20630.5 29310.3 28997.8 30415.0 33229.2 21310.5 21677.8 23731.8 21830.8 22140.300000000003 True False 24122.836179051483 32220.032878975562 29689.217526768916 28710.946156760423 26718.176797808097 20192.9398650088 19624.321850319127 23108.865395920562 22150.03415018403 26154.161127481646 0.9223326285049251 1.2319275973688242 1.1351622933749073 1.0977582502767493 1.0215650453316893 0.7720736966704295 0.7503326814676059 0.88356362428458 0.8469028711041221 1.0 14.674752877088562 -6.596888373343164 4.163228162954214 0.8378730439261283 1.1050460196573915 0.5978855604261398 0.09573886840907136 0.13921500846210869 4.7051585637377284 0.031923013502501964 0.03218767004478938 2.529948185151947e-07 6.596888373343164 0.2671729757312632 S(ph)LEGGGCPAR ddPTM_PC-9_Lapatinib_30min_R1 4 SLEGGGCPAR 10 0 Q9Y613 Q9Y613 FHOD1 FH1/FH2 domain-containing protein 1 1 S(1)LEGGGCPAR;S(1)LEGGGCPAR;S(1)LEGGGCPAR;S(1)LEGGGCPAR 98.75399999999999 0.0046373000000000004 108172000.0 29710.5 15120.6 27785.7 18393.5 18385.6 21259.3 16743.1 16625.5 28288.700000000004 12862.6 True False 29286.822821761587 15085.58917970689 25501.267001903714 19746.21934891727 17304.19515548035 20350.089296848793 17609.975793382524 17397.981424371723 25102.528712782805 15085.883271662835 1.9413396149480786 0.999980505486444 1.6904059605051451 1.30892033256073 1.1470455421052057 1.3489491420813382 1.167314864914865 1.1532623652903313 1.663974741202932 1.0 13.880911547651062 -4.744871623202041 24.989950718803673 1.2892330983624876 1.941341512654903 0.43018674086197417 0.229394193658357 946.549437183272 1427649.6886457736 0.05393682899791138 1.4640822691664301 1.7994027372743145e-05 4.744871623202041 0.6521084142924154 S(ph)LEITSPTSVEQKPK ddPTM_PC-9_Lapatinib_30min_R1 1 SLEITSPTSVEQKPK 15 1 A0A087WU98;Q6P4D5-3 A0A087WU98 FAM122C 1 S(1)LEITSPTSVEQKPK 120.9 0.00037943 0.0 12992.0 9122.4 6595.5 7141.7 9858.6 8000.6 7254.4 5913.2 8696.9 6733.3 True False 12806.731697558997 9101.277643278587 6053.243449366252 7666.924442012808 9278.73653075335 7658.432988309513 7629.997335948185 6187.948859197911 7717.363539582972 7897.1419334417105 1.621691974830393 1.1524774051151052 0.766510656688697 0.9708479987609175 1.1749486851010054 0.9697727421965983 0.9661719898483451 0.7835681454570358 0.9772350053508044 1.0 12.94711490447102 -4.830761360624794 3.207800139188407 0.9530093799693156 1.68162514029364 0.7748995078775702 0.10927314673079308 0.1414740140378557 2.3398701057009417 0.029252678847932454 0.2437012669983394 1.4765176383479306e-05 4.830761360624794 0.7286157603243244 S(ph)LELNGAVEPSEGAPR ddPTM_PC-9_AZD4547_30min_R2 2 SLELNGAVEPSEGAPR 16 0 F5GYK2;Q9NRL3;Q9NRL3-3;M0R2A7;M0QYS2;M0R0P4;R4GN16;Q9NRL3-2 F5GYK2 STRN4 Striatin-4 1 S(1)LELNGAVEPSEGAPR;S(1)LELNGAVEPSEGAPR 151.03 3.102e-05 11010000.0 34631.0 59258.0 41165.0 69980.0 53889.0 49255.0 37718.0 51639.0 43795.0 52501.0 True False 45642.93763045167 78411.98964665126 40619.125203266834 53847.19218022221 46407.44254184986 46175.07706362293 41074.82893055205 43659.379096170785 46109.91429073546 50662.95597006069 0.9009134338198583 1.547718409738841 0.8017519788476364 1.0628513703788474 0.9160034516989961 0.9114169550412755 0.8107467901167325 0.8617613848266439 0.9101307534835541 1.0 15.628643634233805 -5.2907603071548195 24.996239578102355 0.9066702755982393 1.2243161825623883 0.37486522076938444 0.1626742183196791 570.4125403288868 486278.61763615144 0.03919759852248566 0.08161535673013577 5.119643174308906e-06 5.2907603071548195 0.31764590696414896 S(ph)LELSSLAGPGEDPLSADSLGKPTR ddPTM_PC-9_AZD4547_30min_R2 2 SLELSSLAGPGEDPLSADSLGKPTR 25 1 G5E953;Q13615-3;Q13615-2;Q13615 G5E953 MTMR3 Myotubularin-related protein 3 1 S(1)LELSSLAGPGEDPLSADSLGKPTR;S(1)LELSSLAGPGEDPLSADSLGKPTR 153.31 6.757299999999999e-08 47626000.0 34329.0 38144.0 63224.0 83564.0 68140.0 58641.0 53253.0 76802.0 54583.0 59933.0 True False 45244.90791244194 50473.302053425155 62385.60845017226 64299.61085093008 58679.93718201588 54974.16899985615 57992.41383526933 64934.01563438688 57468.14594659699 57834.76391218547 0.7823133501701574 0.8727156236007511 1.0786870081270954 1.1117813318743832 1.0146135855436997 0.9505384872552992 1.0027258678417574 1.1227505956967454 0.993660941261122 1.0 15.819649322919588 -5.090442410080884 3.7073271853531358 1.0362397652040618 0.7961958507849303 0.7202810650806506 0.05277140408064567 0.12217448336491718 3.0275588627845154 0.014662880443977172 0.0497695422179278 8.120029180033766e-06 5.090442410080884 -0.24004391441913153 S(ph)LELSSLAGPGEDPLSADSLGKPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLELSSLAGPGEDPLSADSLGKPTR 25 1 G5E953;Q13615-3;Q13615-2;Q13615 G5E953 MTMR3 Myotubularin-related protein 3 1 S(0.569)LELS(0.216)S(0.216)LAGPGEDPLSADSLGKPTR;S(1)LELSSLAGPGEDPLSADSLGKPTR;S(1)LELSSLAGPGEDPLSADSLGKPTR;S(1)LELSSLAGPGEDPLSADSLGKPTR 172.1 2.0510999999999998e-11 47441400.0 62434.0 66608.6 70007.1 83651.1 96972.0 79328.4 85672.2 79615.1 70343.5 66855.8 True False 73002.84307229104 73221.06160709813 71676.33476740532 78964.4000675255 77971.03271932677 75168.279054333 77556.70900298496 77525.28798417111 71372.1406106725 78976.22730977832 0.9243647811377831 0.9271278725418729 0.90756848242776 0.9998502430078556 0.9872721877874877 0.9517836140677001 0.9820260051011882 0.9816281509635044 0.9037167644222944 1.0 16.269130831527583 -5.750784602291145 24.99985719994396 0.9717308700834557 0.9204311188743436 0.44387543924020123 0.026990563038118275 201.5676918676658 472944.3500033881 0.007256001789002049 0.012404314220186745 1.775069646653708e-06 5.750784602291145 -0.05129975120911212 S(ph)LELSSLAGPGEDPLSADSLGKPTR ddPTM_PC-9_Lapatinib_30min_R1 2 SLELSSLAGPGEDPLSADSLGKPTR 25 1 G5E953;Q13615-3;Q13615-2;Q13615 G5E953 MTMR3 Myotubularin-related protein 3 1 S(1)LELSSLAGPGEDPLSADSLGKPTR;S(1)LELSSLAGPGEDPLSADSLGKPTR 196.81 1.5299e-25 33124000.0 25521.0 22092.9 36638.0 25817.0 29185.0 35238.0 29066.0 26389.0 42113.0 21823.8 True False 25157.065860021798 22041.74524743372 33625.76506676989 27715.668302987324 27468.395679917656 33730.95288379005 30570.895258969744 27615.129277780823 37369.7904704501 25596.0147516144 0.982850889255527 0.8611397305919858 1.3137109582517739 1.082811858484307 1.073151267745115 1.3178204971015093 1.1943615268092298 1.0788839413385272 1.4599847215704975 1.0 14.64363158252269 -5.253066755256326 24.987379132667076 1.189614408242562 0.9219952881130926 0.3826263763368968 0.13621730243374777 603.268020633829 1800391.3553141542 0.03307575376500516 0.08451632528513815 5.583843590711953e-06 5.253066755256326 -0.2676191201294693 S(ph)LEPAENVHGAGGGAFPASQTPSKPASADGHR ddPTM_PC-9_AZD4547_30min_R2 2 SLEPAENVHGAGGGAFPASQTPSKPASADGHR 32 1 P12931;P12931-2 P12931 SRC Proto-oncogene tyrosine-protein kinase Src 1 S(1)LEPAENVHGAGGGAFPASQTPSKPASADGHR;S(1)LEPAENVHGAGGGAFPASQTPSKPASADGHR 106.67 5.746299999999999e-16 78124000.0 23659.4 20258.0 78693.0 108694.0 85750.0 92796.0 57951.0 141452.0 73406.0 86407.0 True False 31182.597053908605 26806.002333218497 77649.47940290725 83636.27760555985 73845.0926527421 86993.45145053213 63108.526734037434 119593.84364359411 77286.0912986809 83381.9172302438 0.3739731357795913 0.3214846003024692 0.9312508273045884 1.0030505460148353 0.885624786592907 1.0433131587789681 0.7568610656885577 1.4342899229980255 0.92689271086523 1.0 16.347446924480174 -5.298052595211257 4.4956023636373965 1.0074731149748377 0.34013987040671945 0.7143249136529102 0.16473557821068074 0.09628847050840875 4.647700717434084 0.04290585701480234 0.10052925589401765 5.034396360642764e-06 5.298052595211257 -0.6673332445681183 down S(ph)LEPAENVHGAGGGAFPASQTPSKPASADGHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLEPAENVHGAGGGAFPASQTPSKPASADGHR 32 1 P12931;P12931-2 P12931 SRC Proto-oncogene tyrosine-protein kinase Src 1 S(1)LEPAENVHGAGGGAFPASQTPSKPASADGHR 71.556 9.0567e-06 17575000.0 9335.8 27747.0 65791.0 49602.0 91774.0 53231.0 56975.0 33427.0 44884.0 31852.0 True False 10916.16654954503 30501.538786465364 67359.7069537568 46822.96075185371 73791.54350517127 50439.47265218008 51577.91553672106 32549.576668834117 45540.34358781447 37626.51545970675 0.290118987000932 0.8106394762791325 1.7902191082746035 1.2444139506352958 1.9611580451608042 1.340529996889943 1.3707863964164977 0.8650701844472046 1.210325830904603 1.0 15.199462069120765 -5.002129408427982 4.253242880702776 1.361870697192358 0.358704672036824 0.5396309337194827 0.3115968362133878 0.14569054358121777 6.446016024504647 0.08219379748541915 0.319127300985549 9.95108856686003e-06 5.002129408427982 -1.0031660251555339 S(ph)LEPAENVHGAGGGAFPASQTPSKPASADGHR ddPTM_PC-9_Lapatinib_30min_R1 3 SLEPAENVHGAGGGAFPASQTPSKPASADGHR 32 1 P12931;P12931-2 P12931 SRC Proto-oncogene tyrosine-protein kinase Src 1 S(1)LEPAENVHGAGGGAFPASQTPSKPASADGHR;S(0.999)LEPAENVHGAGGGAFPASQTPSKPASADGHR;S(1)LEPAENVHGAGGGAFPASQTPSKPASADGHR 81.682 8.1977e-08 74153000.0 51509.2 58935.0 142024.0 65298.0 109744.0 136703.0 80515.0 107512.0 162413.0 80559.0 True False 50774.66936236961 58798.53962845564 130347.33494849391 70100.23274774244 103289.07368500542 130856.53136025732 84683.67273707941 112507.40001185259 144120.33765528983 94483.51581188005 0.537391828892817 0.6223153226593047 1.3795775255444556 0.7419308240742696 1.09319676345086 1.3849667874425546 0.8962798643700721 1.1907622091017307 1.5253490137077288 1.0 16.52777502919129 -4.676769645101138 0.9400915915450703 1.1654515336536115 6.029853929553751e-16 0.43798614936838753 0.24101049207231778 2.317417043564065 1.4201347941394646 0.0811919429902555 2.895937492437277 2.104894604570704e-05 4.676769645101138 -1.1654515336536109 S(ph)LEQDALR ddPTM_PC-9_Lapatinib_30min_R1 1 SLEQDALR 8 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 S(1)LEQDALR 82.48899999999999 0.016397 1426600.0 8198.3 11388.0 9727.0 9787.9 9851.3 8479.4 7774.5 9362.6 9264.4 6783.1 True False 8081.390738615907 11361.63178567664 8927.28360730582 10507.734817477234 9271.865902400996 8116.755828446828 8177.025569079342 9797.620575851715 8220.945713543037 7955.549797087383 1.0158180068930742 1.428139107348214 1.1221453997527864 1.3208056118666034 1.165458848085588 1.0202633426313872 1.0278391535017535 1.2315453772206586 1.033359846047701 1.0 12.95774592133063 -6.547605813569084 6.468094313067035 1.0760708390689167 1.231201524677269 0.281953967052084 0.11931241157350851 0.21824984307516182 31.969206780164292 0.03706671288094619 0.03770225215533968 2.833963069152446e-07 6.547605813569084 0.1551306856083523 S(ph)LEQNIQLPAALLSR ddPTM_PC-9_AZD4547_30min_R2 2 SLEQNIQLPAALLSR 15 0 P33993;P33993-3 P33993 MCM7 DNA replication licensing factor MCM7 1 S(1)LEQNIQLPAALLSR;S(1)LEQNIQLPAALLSR 111.58 0.00040810000000000005 2203300.0 11009.9 8569.599999999999 12634.7 18505.4 16652.1 14628.900000000001 12764.2 15845.900000000001 10253.2 13253.0 True False 14510.819179853597 11339.555612338294 12467.155622633682 14239.265935579935 14340.24335116886 13714.152570419938 13900.189072468122 13397.280257557508 10795.163219677335 12789.016503899244 1.134631359294078 0.8866636155236 0.9748330232299388 1.1133980420807592 1.1212936778052216 1.0723383276766145 1.0868849116138126 1.0475614175236079 0.8440964335596876 1.0 13.642617702447406 -8.199585798697708 10.702639001714887 0.9221787314140046 1.0523417855780173 0.3103131728337206 0.0790433505256801 0.8433506694164002 144.04126143660756 0.055639284140491206 0.020983243009788616 6.31559396843939e-09 8.199585798697708 0.13016305416401264 S(ph)LEQNIQLPAALLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLEQNIQLPAALLSR 15 0 P33993;P33993-3 P33993 MCM7 DNA replication licensing factor MCM7 1 S(1)LEQNIQLPAALLSR 106.31 0.004312399999999999 0.0 3969.5 3874.0 4867.0 4928.9 6837.3 5978.5 5493.4 4702.0 5628.6 4159.1 True False 4641.457948801283 4258.58511762593 4983.047738200288 4652.749712709406 5497.580146968727 5664.976935452251 4973.025383228143 4578.577482180813 5710.907626734967 4913.111906582516 0.9447083716091883 0.8667795887002573 1.014234528532532 0.9470066632261559 1.1189609053282805 1.153032343485276 1.0121946085871474 0.9319098708186355 1.1623809380534518 1.0 12.262421384575967 -5.75922284886947 1.6560822639978445 1.0580026646966627 0.9133303950827992 0.3531499319262944 0.07640670510174552 0.43012237647678303 2.3947962114140595 0.024897046381662135 0.053940065166614405 1.7409133319401914e-06 5.75922284886947 -0.14467226961386348 S(ph)LEQNIQLPAALLSR ddPTM_PC-9_Lapatinib_30min_R1 2 SLEQNIQLPAALLSR 15 0 P33993;P33993-3 P33993 MCM7 DNA replication licensing factor MCM7 1 S(1)LEQNIQLPAALLSR;S(1)LEQNIQLPAALLSR 102.57 0.003999 1746600.0 9688.0 8265.0 9898.7 7933.0 10156.4 7312.3 7508.1 11133.5 11306.1 5569.5 True False 9549.847343438392 8245.862900300084 9084.867096086986 8516.41928371222 9559.020520250675 6999.569974803849 7896.8326805845545 11650.803054840007 10032.687959488898 6532.180654107733 1.461969264036354 1.2623445885739106 1.3907862591604854 1.30376358748693 1.463373569474005 1.0715518056596 1.2089121686520818 1.783600863444193 1.5358864812135724 1.0 12.673348975313889 S(ph)LESCLLDLR ddPTM_PC-9_AZD4547_30min_R2 5 SLESCLLDLR 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 S(1)LESCLLDLR;S(1)LESCLLDLR;S(1)LESCLLDLR;S(1)LESCLLDLR;S(1)LESCLLDLR 171.49 0.00011253 28043340.0 30312.699999999997 32460.999999999996 43556.5 57697.1 53159.7 47580.1 36142.399999999994 49744.8 39290.200000000004 44648.4 True False 39951.50805667157 42953.383440547244 42978.912350688486 44395.92500630893 45779.39325821556 44604.90882539612 39359.00358289373 42057.88418178499 41366.99975946696 43085.273105915294 0.9272659815445505 0.9969388689948924 0.9975313895547245 1.0304199510856458 1.0625299541603783 1.035270420956719 0.9135140790714874 0.9761545221819831 0.9601192420847757 1.0 15.394907208312814 -9.767103437831029 10.122763699144759 0.9999986066389366 0.991517423968052 0.0024050395479793263 0.04468859463169146 0.0 0.0 0.04683203945304911 0.011358437960471474 1.709608081703534e-10 9.767103437831029 -0.008481182670884602 S(ph)LESCLLDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SLESCLLDLR 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 S(0.999)LES(0.001)CLLDLR;S(1)LESCLLDLR;S(0.97)LES(0.03)CLLDLR;S(0.999)LES(0.001)CLLDLR;S(0.976)LES(0.024)CLLDLR 152.96 0.00016587 22440540.0 20465.199999999997 21834.399999999998 26684.0 27927.0 27957.9 28574.4 30034.100000000002 29588.8 24687.100000000002 20596.300000000003 True False 23929.554153875273 24001.97493347745 27320.24775963355 26362.340730555607 22479.75019246442 27075.908161643674 27189.052619946204 28812.12535192505 25048.102134095327 24330.24614977892 0.9835311162313379 0.9865076902929545 1.122892369910602 1.0835213325942925 0.9239425714839588 1.112849742454813 1.1175001047078705 1.1842101873756363 1.0295046741367608 1.0 14.570463295685594 S(ph)LESCLLDLR ddPTM_PC-9_Lapatinib_30min_R1 5 SLESCLLDLR 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 S(0.999)LES(0.001)CLLDLR;S(1)LESCLLDLR;S(0.999)LES(0.001)CLLDLR;S(1)LESCLLDLR;S(1)LESCLLDLR 173.04 0.0001234 18981700.0 41347.2 43386.8 48504.600000000006 40957.700000000004 51428.8 45525.1 38978.0 35235.7 49245.4 36582.0 True False 40757.58134585217 43286.340530277026 44516.739021170586 43969.86588888192 48403.85909691111 43578.09759719139 40996.09011918124 36872.87925624698 43698.86447494844 42905.149957548994 0.9499461343493344 1.0088844945910966 1.0375616695248968 1.0248155741766751 1.1281596532071936 1.015684542305719 0.9555051120842927 0.8594045072148581 1.0184992831439759 1.0 15.388863206115618 -7.240234329244771 4.643843570905686 0.9459435682186016 1.0322850405691935 0.25224857025847025 0.05694784558467729 0.24119495765842808 13.878062680998541 0.023465336966441572 0.017102667365575783 5.7512953497171555e-08 7.240234329244771 0.08634147235059186 S(ph)LESINSR ddPTM_PC-9_AZD4547_30min_R2 3 SLESINSR 8 0 P62888;A0A0C4DH44;E5RI99;E5RJH3 P62888 RPL30 60S ribosomal protein L30 1 S(1)LESINSR;S(1)LESINSR;S(1)LESINSR 118.23 0.003512 91724000.0 41755.0 33315.1 64328.0 72730.0 63947.0 65199.0 50722.6 65341.0 43288.0 66100.0 True False 55032.22144204645 44083.554562711375 63474.968688831505 55963.22216729872 55069.06285556747 61122.09622314797 55236.81313730366 55244.049836807324 45576.1153057965 63785.85911927414 0.8627652304430183 0.6911179871431828 0.9951260289547673 0.8773609533525644 0.8633428100826078 0.9582389743917197 0.8659727077441336 0.8660861607822142 0.714517542525735 1.0 15.960949003544181 -5.254537675747433 24.9989283572457 0.8876048980696974 0.7769416217228545 0.21922138012703807 0.08688950103315457 820.1996137434988 2970856.704898636 0.021516443641388997 0.05434730561923263 5.564963552069196e-06 5.254537675747433 -0.11066327634684292 S(ph)LESINSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLESINSR 8 0 P62888;A0A0C4DH44;E5RI99;E5RJH3 P62888 RPL30 60S ribosomal protein L30 1 S(1)LESINSR;S(1)LESINSR 92.611 0.0078449 46091000.0 38083.0 42853.0 49835.0 56558.0 49342.0 41005.0 45765.0 41284.0 40797.0 28997.0 True False 44529.699726464074 47107.16263438926 51023.25540028997 53389.23862351003 39673.78930451069 38854.62561482303 41429.80789009281 40200.338744013745 41393.578944658824 34253.926559874315 1.299988182336649 1.3752339473271207 1.4895593155168247 1.5586311989718333 1.1582260280485712 1.1343115816782903 1.2094907664870296 1.1735979720090008 1.2084331083125528 1.0 15.063981754593817 -6.279414189863009 24.46272670501268 1.1584789037281968 1.4310736495622647 0.7301524915911494 0.08427270564317407 340.4192155458609 463290.52745631075 0.02683615336393445 0.030495241161427798 5.255158389745209e-07 6.279414189863009 0.27259474583406784 S(ph)LESINSR ddPTM_PC-9_Lapatinib_30min_R1 3 SLESINSR 8 0 P62888;A0A0C4DH44;E5RI99;E5RJH3 P62888 RPL30 60S ribosomal protein L30 1 S(1)LESINSR;S(0.997)LES(0.003)INSR;S(1)LESINSR 115.57 0.0036279000000000003 94740000.0 53905.0 37598.6 56322.0 46689.0 60487.0 57497.0 38242.0 21297.4 54004.0 34071.9 True False 53136.30481503371 37511.54275175111 51691.4225692072 50122.66480993824 56929.2735820175 55037.98734205337 40221.98364045691 22286.954953981185 47921.50083266894 39961.182517047 1.3296980086203996 0.9386995176068452 1.2935408642413475 1.2542838237721434 1.424614338120052 1.3772862531927021 1.0065263615084128 0.5577151012604249 1.1992012701882924 1.0 15.286311655028063 -7.444003966320084 5.647129998003991 0.8854121079737022 1.2595278184878602 0.41291982444520325 0.19237780100554644 0.20589730548932278 11.176283277198502 0.08218824972358073 0.05416253897227883 3.597460496557948e-08 7.444003966320084 0.37411571051415804 S(ph)LESLIYMSTR ddPTM_PC-9_AZD4547_30min_R2 1 SLESLIYMSTR 11 0 O95171-2;O95171;O95171-3;F2Z2X8 O95171-2 SCEL Sciellin 1 S(1)LESLIYMSTR 202.18 2.164e-05 17795000.0 5768.5 3002.0 10051.0 10592.0 12169.0 8224.1 9637.9 8822.2 13750.0 9857.5 True False 7602.7630077462545 3972.337792690393 9917.717172793265 8150.178044768701 10479.544402229976 7709.845726909787 10495.65442891372 7458.93170398803 14476.79692881865 9512.391925389491 0.7992482928982086 0.417596102415402 1.0426102341643348 0.8567958625648182 1.1016729004046881 0.8105054740576306 1.1033664835549728 0.7841278789280561 1.521888189886151 1.0 13.215592442256945 -5.113229686954674 0.4607027425855386 1.0973648285011073 0.38259138611746907 0.3049101935833841 0.22773105195115165 4.510390089772275 0.9307468818258972 0.15990964782022787 1.7036740192378426 7.704958662444956e-06 5.113229686954674 -0.7147734423836383 S(ph)LESLIYMSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLESLIYMSTR 11 0 O95171-2;O95171;O95171-3;F2Z2X8 O95171-2 SCEL Sciellin 1 S(0.976)LES(0.021)LIY(0.002)MSTR 71.085 0.026955 8107700.0 30671.0 35923.0 40787.0 52907.0 58977.0 45288.0 45715.0 42567.0 34054.0 39586.0 True False 35862.99452013706 39489.19803316373 41759.5167655589 49942.79231680829 47420.88021993694 42913.01755503247 41384.544252061474 41449.66135346461 34551.9753261615 46762.62843739641 0.7669157127929354 0.84446061636655 0.8930104692781452 1.0680065254173925 1.0140764496038064 0.9176776196933067 0.8849918329006066 0.886384335922337 0.7388800946554586 1.0 15.513068402811312 -5.062384805194798 2.384333876969113 0.9283025451550759 0.7694109127681951 0.26426662044138394 0.08523562966520974 0.517455675586949 5.123524178616205 0.024802252478534053 0.13167140939834576 8.661940472608145e-06 5.062384805194798 -0.15889163238688087 S(ph)LESLIYMSTR ddPTM_PC-9_Lapatinib_30min_R1 1 SLESLIYMSTR 11 0 O95171-2;O95171;O95171-3;F2Z2X8 O95171-2 SCEL Sciellin 1 S(1)LESLIYMSTR 77.67399999999999 0.019239 13038000.0 5141.2 5218.3 13000.0 3150.2 4261.4 4513.8 9346.8 5272.5 11543.0 4706.0 True False 5067.885545219388 5206.217346961398 11931.19018145119 3381.876216759139 4010.7528302347514 4320.755296181722 9830.731569756363 5517.4795982075675 10242.90578682131 5519.425829649164 0.9181907143304293 0.9432534302743453 2.161672345945734 0.612722468085798 0.7266612423143459 0.7828269514867936 1.7811148973046786 0.9996473851625758 1.8557919071579203 1.0 12.430302479962291 -7.250182670914611 24.826102111649597 1.4091091831575426 1.0400132391202173 0.1333038669717459 0.47981008346979914 1535.6650067721753 3386837.1169384336 0.18752439673872118 0.14391141917233807 5.6210484554811326e-08 7.250182670914611 -0.3690959440373254 S(ph)LESLR ddPTM_PC-9_AZD4547_30min_R2 1 SLESLR 6 0 Q5VT97-2;Q5VT97 Q5VT97-2 SYDE2 Rho GTPase-activating protein SYDE2 1 S(1)LESLR 104.75 0.034225 0.0 7802.1 7493.7 8040.2 14512.0 11225.0 10664.0 8855.1 11775.0 9326.3 9917.3 True False 10283.005506238544 9915.891977709527 7933.58169462665 11166.482608164975 9666.602507603868 9997.178394203125 9643.186745398261 9955.444312581782 9819.26917798119 9570.09834559119 1.0744931906552224 1.0361327145898809 0.8289968825954165 1.1668095984937519 1.0100839258414869 1.0446265057253759 1.0076371628762564 1.0402656224706526 1.026036392040296 1.0 13.22431803507534 -5.783154646391972 24.999998418611806 1.0412078796632749 0.9854998249831035 0.1282111854712592 0.07401963364398896 533.1034864794858 613740.7239080239 0.020615253753007913 0.03060557509865184 1.64757560766535e-06 5.783154646391972 -0.05570805468017137 S(ph)LESLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLESLR 6 0 Q5VT97-2;Q5VT97 Q5VT97-2 SYDE2 Rho GTPase-activating protein SYDE2 1 S(1)LESLR 104.75 0.03475 2905500.0 7670.9 7469.7 10832.0 6660.8 10224.0 9411.4 13264.0 8053.1 10171.0 6361.8 True False 8969.431862818925 8211.242450472488 11090.275960588759 6287.616970604963 8220.680593598105 8917.849616177187 12007.537896956 7841.71465796476 10319.73163335845 7515.143980018912 1.1935143074659167 1.0926260990214354 1.4757236840804813 0.8366595486822782 1.0938819822288244 1.1866505338936628 1.5977788221864224 1.0434550128133442 1.3731914732167885 1.0 12.875585029158943 -7.01100401087217 24.326001653289815 1.2765114255828038 1.1381379030502314 0.05669140379969739 0.2133737206061819 1001.9742403183136 2215014.0307330242 0.07633728643725386 0.06301163717472413 9.749806333645599e-08 7.01100401087217 -0.1383735225325724 S(ph)LESLR ddPTM_PC-9_Lapatinib_30min_R1 2 SLESLR 6 0 Q5VT97-2;Q5VT97 Q5VT97-2 SYDE2 Rho GTPase-activating protein SYDE2 1 S(1)LESLR;S(1)LESLR 110.81 0.028352999999999996 5441000.0 19636.3 12602.6 20001.7 15839.8 18326.3 17667.5 17994.9 16076.099999999999 18335.6 12135.5 True False 19356.282761143593 12573.419454001432 18357.23743479478 17004.711732023814 17248.383064892074 16911.902209954045 18926.587872278087 16823.054294688416 16270.451645572266 14233.105005462692 1.3599480052816737 0.8833925871533815 1.289756341132117 1.194729591715748 1.2118496321267995 1.1882089117914345 1.3297581845292386 1.181966569362883 1.1431414044460178 1.0 13.796962805105288 -8.665406920585536 2.3758544907957324 1.0003899682864883 1.2001859420446066 0.20306755985017833 0.12300718973691448 0.9075465195386762 10.250928497231941 0.11313647455053405 0.030744954130173276 2.160693071962572e-09 8.665406920585536 0.1997959737581183 S(ph)LESVLSLGPR ddPTM_PC-9_AZD4547_30min_R2 2 SLESVLSLGPR 11 0 Q13470-2;Q13470 Q13470-2 TNK1 Non-receptor tyrosine-protein kinase TNK1 1 S(0.998)LES(0.002)VLSLGPR;S(1)LESVLSLGPR 137.4 9.098299999999999e-05 13446900.0 4890.95 2837.3 4883.8 7467.4 5027.04 8152.0 4686.2 6032.099999999999 5391.33 3928.1 True False 6446.170361920181 3754.401738574433 4819.037620981766 5745.906300179929 4329.122269026723 7642.2541513075685 5103.262721627685 5099.977548868332 5676.304697181662 3790.5784146205883 1.7005769718565233 0.9904561594329195 1.2713198604187481 1.5158389226344644 1.1420743209872468 2.016118205556897 1.3463018472178176 1.3454351792848496 1.4974771858795124 1.0 11.888202294597766 S(ph)LESVLSLGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SLESVLSLGPR 11 0 Q13470-2;Q13470 Q13470-2 TNK1 Non-receptor tyrosine-protein kinase TNK1 1 S(0.978)LES(0.022)VLSLGPR;S(1)LESVLSLGPR;S(0.997)LES(0.003)VLSLGPR;S(1)LESVLSLGPR;S(0.999)LES(0.001)VLSLGPR;S(0.997)LES(0.003)VLSLGPR 122.18 0.00069485 22250800.0 11156.73 20178.600000000002 20750.8 18757.7 20185.2 11274.31 12674.52 10524.27 12909.4 9354.259999999998 True False 13045.344033538151 22181.79805227844 21245.577769847223 17706.766882283922 16230.05496067062 10683.065336311553 11473.897710021614 10248.019063885806 13098.175552814628 11050.113289718583 1.180562017013527 2.007381958058038 1.9226570092828696 1.6024059136804438 1.468768195867425 0.9667833311945728 1.0383511380555106 0.9274130314501776 1.1853431009618367 1.0 13.431773540268178 -6.561077373785331 2.3922784706166684 1.0157326917245444 1.7215204824183308 0.6680865256519427 0.21822448106021114 0.1696649727891147 1.964565544143191 0.07814296345970372 0.081828872582771 2.74740463264431e-07 6.561077373785331 0.7057877906937864 S(ph)LESVLSLGPR ddPTM_PC-9_Lapatinib_30min_R1 3 SLESVLSLGPR 11 0 Q13470-2;Q13470 Q13470-2 TNK1 Non-receptor tyrosine-protein kinase TNK1 1 S(0.999)LES(0.001)VLSLGPR;S(1)LESVLSLGPR;S(1)LESVLSLGPR 142.89 0.00014554 14021600.0 2438.13 3392.97 6120.200000000001 3306.9 6147.200000000001 5352.7 5927.1 5751.5 4709.700000000001 3468.93 True False 2403.3618191017176 3385.113786428455 5617.020780655199 3550.1004574950152 5785.6337818602005 5123.777498753136 6233.976236476971 6018.735686883037 4179.2439906603395 4068.5299284413204 0.5907199557021474 0.8320238135068392 1.380602055152416 0.8725757263521179 1.4220452801429222 1.259368270326596 1.5322429344559958 1.4793391698580554 1.0272123012897276 1.0 11.990291887982925 -4.625681544124561 0.9358248359300658 1.2968160249574447 4.864466372721714e-11 0.49093429238302333 0.21653949680594642 2.125301246902238 1.2120024159598686 0.07213962714492078 3.00571429538242 2.3676551957845666e-05 4.625681544124561 -1.2968160249088 S(ph)LETENR ddPTM_PC-9_AZD4547_30min_R2 1 SLETENR 7 0 P05783;F8VZY9;CON__P05784 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(1)LETENR 84.213 0.020106 10654000.0 10310.0 22299.0 23198.0 29072.0 34052.0 26908.0 24062.0 30653.0 32547.0 29918.0 True False 13588.365538677976 29506.715669288158 22890.37936269606 22369.899557922563 29324.467580305278 25225.438506303257 26203.471385729474 25916.283185865766 34267.3679739826 28870.579926330465 0.47066479348013207 1.0220340479678944 0.79286177905348 0.77483374476731 1.0157214595319182 0.8737420090164945 0.907618463245051 0.897671028846555 1.186930365147607 1.0 14.81731246697918 -3.66014701478642 0.3700528803510959 1.0007723278897314 1.2163896598749948e-34 0.4318009928025208 0.13745127561312984 15.805856743363915 0.9005160457633612 0.11342504555687856 8.306341620351219 0.00021870211612250027 3.66014701478642 -1.0007723278897314 S(ph)LETENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLETENR 7 0 P05783;F8VZY9;CON__P05784 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(1)LETENR;S(1)LETENR 101.65 0.011132 17663100.0 32467.0 45106.0 52922.0 55611.0 76992.0 49636.0 42211.0 46704.0 47956.0 36745.0 True False 37963.02184752013 49583.82558483103 54183.861187802664 52495.29596329461 61905.97029169646 47033.00078081591 38212.4684988246 45478.06948697844 48657.26577616143 43406.57762674002 0.874591454179367 1.14231133380775 1.248286876098323 1.2093857390626348 1.4261886948110865 1.0835454751871958 0.8803382019061632 1.0477229943823607 1.1209652646327684 1.0 15.405626057943737 -6.993159715282676 24.999068306551443 1.0113346938054106 1.1906005218565152 0.2456566013238417 0.13856676739989834 243.90910978419922 891404.4101467599 0.051124419480313064 0.0449839269658345 1.0158750279677637e-07 6.993159715282676 0.17926582805110458 S(ph)LETENR ddPTM_PC-9_Lapatinib_30min_R1 2 SLETENR 7 0 P05783;F8VZY9;CON__P05784 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(1)LETENR;S(1)LETENR 101.46 0.011192 23511000.0 53815.0 41846.0 63881.0 47361.0 43988.0 54160.0 49899.0 54141.0 56449.0 40033.0 True False 53047.58823153764 41749.10815801055 58628.95076779105 50844.08593166451 41400.712323735446 51843.7030531264 52482.52606231786 56656.588511437774 50091.119185677555 46952.65070938057 1.12981029675795 0.8891746797517779 1.2486824467202593 1.0828799900216597 0.8817545271296916 1.104169887532434 1.1177755732507024 1.206674972668124 1.0668432650527642 1.0 15.518918986998886 -6.969675816247112 24.997851852141856 1.1144646915606329 1.045178396686722 0.04467227068575519 0.11177032326680517 559.9208604650719 461571.01489494607 0.0392245019137624 0.0345923980987023 1.0723194508648576e-07 6.969675816247112 -0.0692862948739108 S(ph)LETVYLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLETVYLER 9 0 Q15435;H7C003;C9J177;Q15435-2;H7C3Q5 Q15435 PPP1R7 Protein phosphatase 1 regulatory subunit 7 1 S(0.999)LET(0.001)VYLER 82.26100000000001 0.016033000000000002 1155400.0 6194.9 6257.6 6510.6 6651.1 7698.5 4968.9 6413.3 5478.5 6266.7 6104.9 True False 7243.574215147762 6878.813172962319 6665.837395588 6278.46043015714 6190.034189144656 4708.3221367514725 5805.785795728882 5334.6951799505705 6358.338632068371 7211.670043638187 1.0044239643961137 0.9538446894184379 0.9243125871334482 0.8705972946856765 0.8583357463234508 0.6528754238978174 0.8050542746129222 0.7397309011186113 0.8816735365863575 1.0 12.816117675151618 -5.806715712358439 1.4197801755170258 0.8002484565638057 0.9819160385922354 0.3326689942055169 0.08704715755177346 0.4307276096587092 1.7533599900468775 0.02857582182852849 0.06381264084662425 1.560573714618741e-06 5.806715712358439 0.1816675820284297 S(ph)LETVYLER ddPTM_PC-9_Lapatinib_30min_R1 1 SLETVYLER 9 0 Q15435;H7C003;C9J177;Q15435-2;H7C3Q5 Q15435 PPP1R7 Protein phosphatase 1 regulatory subunit 7 1 S(1)LETVYLER 90.10799999999999 0.017741 0.0 6152.3 6848.2 7827.5 5465.1 6196.1 6336.3 6573.0 6408.8 6640.4 5582.4 True False 6064.567073806355 6832.343413652155 7183.9531650237805 5867.021685039164 5831.657580001296 6065.311219636727 6913.317778063992 6706.576244474659 5892.488225488022 6547.310401919567 0.9262684524668818 1.0435343666689485 1.0972372965420365 0.8960964617347372 0.8906951438092117 0.9263821091876864 1.0559019434968469 1.0243253844370044 0.8999860803545282 1.0 12.676686662045006 -5.767441817472356 24.99999263047758 0.9573944239718986 1.0244654700571927 0.17315991714194534 0.06615472141316336 266.81728024883455 1111292.4497642273 0.01990063375912904 0.030409753446741343 1.7082765629186662e-06 5.767441817472356 0.06707104608529413 S(ph)LEVIPEKANDETGE ddPTM_PC-9_AZD4547_30min_R2 1 SLEVIPEKANDETGE 15 1 Q9UPR0;Q9UPR0-3 Q9UPR0 PLCL2 Inactive phospholipase C-like protein 2 1 S(1)LEVIPEKANDETGE 85.42 0.044279 0.0 3424.1 3031.3 3340.7 5325.3 6479.7 5344.2 4542.4 5559.8 4791.6 4914.7 True False 4512.8925742955635 4011.108444697663 3296.400135225395 4097.634360064839 5580.105502763547 5010.026329172949 4946.6648002052 4700.660661494027 5044.874193754721 4742.637848918258 0.9515574914337815 0.8457547408163478 0.6950562619866213 0.8639990002608913 1.1765826699241448 1.0563796960199436 1.043019719781783 0.9911489789519128 1.0637274770843825 1.0 12.211473992101793 -6.11820854108397 6.470993545264619 1.0534547966656453 0.8241231263486942 0.6689999157972499 0.07461356152139659 0.14527779507005756 7.1706191444522105 0.022827043968075934 0.02966856171762731 7.617131600341915e-07 6.11820854108397 -0.22933167031695112 S(ph)LFINHHPPGQIAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLFINHHPPGQIAR 14 0 Q8ND76-3;Q8ND76-2;Q8ND76;R4GNF3;R4GN48 Q8ND76-3 CCNY Cyclin-Y 1 S(1)LFINHHPPGQIAR 75.376 0.028477 0.0 5160.4 3964.7 4823.6 4340.0 6791.1 4650.8 4076.5 4408.4 3662.8 3378.9 True False 6033.953797454116 4358.289214210512 4938.612917604867 4096.843870469846 5460.432705319255 4406.903860734522 3690.344408695802 4292.684171085897 3716.3615206631944 3991.4678226423166 1.5117130002214805 1.0919013776053348 1.2372924290131315 1.0264003250207265 1.3680262369507206 1.1040810189513668 0.9245582258640949 1.0754650574244584 0.9310764074262274 1.0 11.962703665453642 -1.5228787452814574 0.24933798096290524 0.9679284175928262 3.5630326225942524 0.4882598292696587 0.1296151289611634 47.38312324793006 0.6435874026420387 0.1687971244055614 51.52400864320813 0.029999999999922644 1.5228787452814574 2.595104205001426 S(ph)LGDEGLNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLGDEGLNR 9 0 Q01970-2;Q01970 Q01970-2 PLCB3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1 S(1)LGDEGLNR;S(1)LGDEGLNR;S(1)LGDEGLNR 101.39 0.0035126999999999997 49700000.0 125336.0 179928.0 149235.0 104182.0 133149.0 80146.0 100882.0 60728.0 76454.0 79197.0 True False 146552.9093011608 197790.06273727363 152793.32837688926 98345.02030260129 107059.40926809424 75943.0026710305 91325.72663756897 59133.95434663468 77571.9951132424 93554.78917689272 1.566492860392851 2.1141628822795338 1.633196223530457 1.0512024148400487 1.1443498532786716 0.8117489584358746 0.9761737206728235 0.6320783240163647 0.8291611343014181 1.0 16.513523888118684 -5.781790275062324 2.000483917055197 0.8775517583610996 1.8667997624304016 0.8300900065792383 0.17862984210774235 0.11900128497834299 0.972400795220614 0.0545724884144934 0.10558180510624429 1.6527597389510744e-06 5.781790275062324 0.989248004069302 S(ph)LGDEGLNR ddPTM_PC-9_Lapatinib_30min_R1 2 SLGDEGLNR 9 0 Q01970-2;Q01970 Q01970-2 PLCB3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1 S(1)LGDEGLNR;S(1)LGDEGLNR 127.87 0.0013484999999999999 55339000.0 39853.0 128535.0 86150.0 82264.0 104177.0 103112.0 122178.0 111167.0 110319.0 99811.0 True False 39284.68891185487 128237.38510466655 79067.07954861692 88313.96898465921 98049.51367986243 98702.14012581186 128503.77901845456 116332.22465508601 97893.71250942898 117063.19836020214 0.33558530317082513 1.0954543093046336 0.6754221707263491 0.7544127464629672 0.8375776081067355 0.8431526005474965 1.097729951158945 0.99375573437805 0.8362466930743779 1.0 16.83692807557076 -6.780853678393031 1.8021183361458293 0.9786646874213412 0.742366025063234 0.2792991540399983 0.18391221418109668 0.4977756110218795 3.3393418225327727 0.07386371188603008 0.06655452620701632 1.6563279160797774e-07 6.780853678393031 -0.23629866235810715 S(ph)LGEQDQMTLRPPEK ddPTM_PC-9_AZD4547_30min_R2 1 SLGEQDQMTLRPPEK 15 1 P48681 P48681 NES Nestin 1 S(0.55)LGEQDQMT(0.45)LRPPEK 91.789 0.042914 0.0 24590.0 27944.0 27245.0 30156.0 30422.0 30544.0 31505.0 41734.0 31791.0 26318.0 True False 32409.108496226138 36976.351525296544 26883.71349843324 23204.0001055556 26198.4304219443 28634.078851513535 34308.88396672792 35284.969251914066 33471.40735738716 25396.61483057576 1.2761192274022215 1.4559559127061132 1.0585549955290545 0.9136650793955261 1.031571750672976 1.1274762027354959 1.350923506758956 1.3893571835185456 1.3179475918613337 1.0 14.632348589436246 -7.251261581283592 23.622210536645504 1.2970034997258029 1.1386262251059336 0.09586525502558185 0.16979183527356984 670.7302468450355 1556736.3239683283 0.07108472428907432 0.054349545899186426 5.6071015119914025e-08 7.251261581283592 -0.15837727461986928 S(ph)LGEQDQMTLRPPEK ddPTM_PC-9_Lapatinib_30min_R1 1 SLGEQDQMTLRPPEK 15 1 P48681 P48681 NES Nestin 1 S(0.82)LGEQDQMT(0.18)LRPPEK 92.773 0.040577999999999996 0.0 6801.5 19795.0 16136.0 11453.0 21256.0 17023.0 17410.0 19944.0 15818.0 15484.0 True False 6704.509362757661 19749.165893701178 14809.360366761266 12295.291826087992 20005.763870903887 16294.965972551174 18311.404612215763 20870.671049151584 14036.410269075584 18160.3887688669 0.3691831407404382 1.087485854243274 0.8154759545759044 0.6770390206164704 1.1016153963179793 0.897280679391969 1.008315672382948 1.1492414240013977 0.7729135343808707 1.0 14.148507467030305 -4.752501353013748 24.999965905670567 0.94303346278686 0.36918204041888475 0.5826147295466293 0.1463221020988537 254.34029843314855 711346.4141361956 0.036371649725825995 0.4311290559511151 1.768066709438933e-05 4.752501353013748 -0.5738514223679752 S(ph)LGGAVGSVASGAR ddPTM_PC-9_AZD4547_30min_R2 2 SLGGAVGSVASGAR 14 0 Q8NHG8 Q8NHG8 ZNRF2 E3 ubiquitin-protein ligase ZNRF2 1 S(1)LGGAVGSVASGAR;S(1)LGGAVGSVASGAR 118.52 0.00011439 34955000.0 18571.6 14236.4 17671.1 33081.0 29313.0 22642.0 24686.0 29329.0 17492.9 22085.1 True False 24476.982486722765 18838.037892024488 17436.76966790838 25454.686546355108 25243.3959292109 21226.192160685234 26883.006176881303 24796.87696337249 18417.538981536854 21311.907371181256 1.1485120529296895 0.883920784936311 0.8181703009598765 1.194388005870177 1.1844738009393727 0.9959780601049378 1.2614077993428918 1.1635221818251584 0.8641900821341654 1.0 14.37937209664015 -5.769880653839997 24.99994983210354 1.1082192301093443 0.9435730095332986 0.18709196709324205 0.13598124694510613 264.8350443214187 784344.8816535175 0.038118008778008146 0.05758860483082289 1.6987104019099161e-06 5.769880653839997 -0.16464622057604572 S(ph)LGGAVGSVASGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLGGAVGSVASGAR 14 0 Q8NHG8 Q8NHG8 ZNRF2 E3 ubiquitin-protein ligase ZNRF2 1 S(1)LGGAVGSVASGAR 156.2 0.00034994 15206000.0 11792.0 12975.0 12219.0 12242.0 15184.0 15641.0 12147.0 13693.0 13678.0 10627.0 True False 13788.152697383732 14263.072251212301 12510.34730081555 11556.120429099507 12208.804199256027 14820.758425593142 10996.34822333568 13333.573258932764 13878.014873766293 12553.59097671428 1.0983433125198556 1.1361746832176502 0.9965552744247489 0.9205430104051513 0.9725348087174578 1.1805991172632788 0.8759524062662917 1.0621322045353618 1.1055015970735937 1.0 13.615812488207972 -5.262388777457622 24.963970055676374 1.0126148846132637 1.1172590019484008 0.1969001416328251 0.08318145172063127 127.11680865603898 3342574.5174170877 0.02168312747859241 0.049591572640109396 5.465264970514344e-06 5.262388777457622 0.10464411733513712 S(ph)LGLGGR ddPTM_PC-9_AZD4547_30min_R2 2 SLGLGGR 7 0 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 S(1)LGLGGR;S(1)LGLGGR 80.219 0.034381999999999996 2393800.0 10629.900000000001 12696.0 17151.0 28735.0 19796.5 15517.5 13188.5 17913.6 15350.8 14925.599999999999 True False 14009.987084344612 16799.73371618828 16923.566533735684 22110.58970132445 17048.097687463694 14547.188271947398 14362.250950490119 15145.464733576642 16162.211948720678 14403.05928699907 0.972709117221418 1.166400372409254 1.174998047047668 1.535131478718732 1.183644206953461 1.010006831331898 0.9971666896805884 1.0515449830334105 1.1221374311296148 1.0 13.81408765992613 -6.6845958969823505 5.603338655481496 1.0372594218124682 1.2236044576078156 0.28921169682310066 0.13317381047966995 0.2777576232684028 14.932390940534862 0.04750590446606061 0.047087817808578944 2.0673028483867442e-07 6.6845958969823505 0.18634503579534734 S(ph)LGLGGR ddPTM_PC-9_Lapatinib_30min_R1 1 SLGLGGR 7 0 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 S(1)LGLGGR 80.165 0.025804 3013900.0 11562.0 8457.9 7136.1 6390.7 5047.3 8957.8 9274.6 9978.7 6839.5 8920.2 True False 11397.12375978888 8438.316252201828 6549.3974041426045 6860.693396750247 4750.427737373601 8574.695775651695 9754.79340703367 10442.346831035336 6069.1634868720685 10462.044684580625 1.0893782337391857 0.8065647305673003 0.6260150478802069 0.6557698426639114 0.45406303266654646 0.8196003777626204 0.9323983696428548 0.998117208046882 0.580112556374094 1.0 13.352877216605467 -6.989306932936722 24.989739981570974 0.8772857847111737 0.7128692909311032 0.12645125862231665 0.18690394362517537 444.250893603838 1038211.3562601852 0.06825651820993422 0.06014011810852329 1.0249273139109423e-07 6.989306932936722 -0.1644164937800705 S(ph)LGPGAGPR ddPTM_PC-9_AZD4547_30min_R2 2 SLGPGAGPR 9 0 H3BUV2;P78549-3;P78549-2;P78549 H3BUV2 NTHL1 Endonuclease III-like protein 1 1 S(1)LGPGAGPR;S(1)LGPGAGPR 82.26100000000001 0.016033000000000002 24836000.0 8958.3 14727.9 26443.0 37961.0 17479.6 18728.8 20127.5 27964.0 22400.0 15936.0 True False 11806.853055784568 19488.405655218114 26092.348542450738 29209.67794160356 15052.85925985859 17557.68517529553 21918.80850786591 23642.806348792954 23584.018269493656 15378.085490540896 0.7677713238781899 1.2672842576668915 1.6967228175770135 1.8994352684260025 0.9788513185934391 1.1417341375878884 1.4253275234650133 1.5374349663575295 1.5336121186216745 1.0 13.908588284329847 S(ph)LGPGAGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLGPGAGPR 9 0 H3BUV2;P78549-3;P78549-2;P78549 H3BUV2 NTHL1 Endonuclease III-like protein 1 1 S(1)LGPGAGPR;S(1)LGPGAGPR 99.973 0.0039689999999999994 18230400.0 33812.9 46928.0 39413.8 34247.6 46218.0 33784.0 42588.0 29930.3 29640.9 25979.7 True False 39536.756134783434 51586.701703652485 40353.57446966888 32328.818004217297 37161.91467868905 32012.30756666703 38553.756329580996 29144.6613387742 30074.34208742645 30689.61395480795 1.2882780537090939 1.680917256880995 1.3148935183444017 1.0534123385137122 1.2108954753686996 1.043099063214246 1.2562476799595264 0.949658779732167 0.9799517886315702 1.0 14.90546287778177 -5.585387647291698 3.9398787222773577 1.0817348380627259 1.489912656518936 0.6356602196166605 0.127730445876487 0.1268634585480096 3.9665116017666926 0.03425750657186195 0.06425559801493501 2.5978397199545787e-06 5.585387647291698 0.40817781845621015 S(ph)LGPGAGPR ddPTM_PC-9_Lapatinib_30min_R1 2 SLGPGAGPR 9 0 H3BUV2;P78549-3;P78549-2;P78549 H3BUV2 NTHL1 Endonuclease III-like protein 1 1 S(1)LGPGAGPR;S(1)LGPGAGPR 102.06 0.0032981 23471000.0 17488.1 14761.1 16978.5 18905.9 20870.7 19127.4 20386.0 22261.0 18773.1 14956.0 True False 17238.716487075242 14726.921579869286 15582.5932689053 20296.302954233575 19643.126459374947 18309.365690147177 21441.487330535925 23295.32732777593 16658.675788493038 17541.124672382663 0.9827600458376798 0.8395654129895016 0.8883463038968682 1.157069648230068 1.1198327830313952 1.0437965656201087 1.222355335304932 1.3280406908259923 0.9496925710083469 1.0 14.098453630596161 -5.759085655586775 24.99951598778848 1.1323495199740776 0.8971580137911581 0.44680751273249153 0.10798504282373562 50.971616348124535 541368.481725945 0.029484635172168983 0.048128857314254224 1.7414633719562678e-06 5.759085655586775 -0.2351915061829195 S(ph)LGPSLATDKS ddPTM_PC-9_AZD4547_30min_R2 1 SLGPSLATDKS 11 1 Q9H3N1 Q9H3N1 TMX1 Thioredoxin-related transmembrane protein 1 1 S(1)LGPSLATDKS 140.01 0.00017169 21104000.0 43712.0 55457.0 92770.0 77833.0 71105.0 47962.0 87176.0 95624.0 77828.0 37538.0 True False 57611.50673391769 73382.39072925746 91539.80918515874 59889.80435786277 61233.29811164127 44962.92855802422 94934.49511771047 80847.50802091895 81941.82919098892 36223.80604567794 1.590432177702973 2.025805643855392 2.52706214994989 1.653327214769817 1.6904159114154529 1.2412535695814602 2.620776375569116 2.231888827998109 2.2620988277063128 1.0 15.144650518182818 -7.271996370971402 24.988769245913527 2.1313483295810607 1.8218863891274208 0.03444077415091518 0.5021903305469838 2072.829264132878 4906440.136912105 0.20719349856153044 0.14136700628830803 5.345688263140843e-08 7.271996370971402 -0.30946194045363984 S(ph)LGPSLATDKS ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLGPSLATDKS 11 1 Q9H3N1 Q9H3N1 TMX1 Thioredoxin-related transmembrane protein 1 1 S(1)LGPSLATDKS;S(1)LGPSLATDKS 111.39 0.002671 30190000.0 84446.0 94230.0 60536.0 64758.0 116176.0 63982.0 65172.0 58710.0 46014.0 48754.0 True False 98741.03991547391 103584.53165562534 61979.40782405842 61129.819208268695 93412.14677639394 60626.67128612623 58998.43635558027 57168.9247083869 46686.8677000645 57592.714263548376 1.7144710260333949 1.798570061859129 1.0761675086268068 1.061415840353248 1.621943816520494 1.0526795283287786 1.024407984760003 0.9926416116937606 0.8106384339939606 1.0 15.813598695372066 -1.5228787514626159 0.2967234843117699 0.9166665987069214 8.523065448952108 0.6048071444747832 0.2104163467760823 37.74080002207692 0.5372245637735109 0.22699520200212306 151.80307695259765 0.02999999957294335 1.5228787514626159 7.606398850245187 S(ph)LGPSLATDKS ddPTM_PC-9_Lapatinib_30min_R1 2 SLGPSLATDKS 11 1 Q9H3N1 Q9H3N1 TMX1 Thioredoxin-related transmembrane protein 1 1 S(0.998)LGPS(0.002)LATDKS;S(1)LGPSLATDKS 148.13 0.00040374 50946000.0 156039.0 168801.0 80109.0 35659.0 56454.0 65096.0 84676.0 59069.0 92888.0 25755.0 True False 153813.85524595217 168410.15165560285 73522.74724968267 38281.48181493685 53133.48671283441 62311.99582618753 89060.10895715005 61813.56138198629 82425.97528599645 30206.717433619662 5.0920413839724095 5.5752549751786225 2.433986659134728 1.2673168443099376 1.7589957210543363 2.062852276587827 2.9483544232458496 2.046351495087932 2.7287299742890125 1.0 14.882581794348646 -5.3008836014463006 5.163657779369046 2.046196560216653 5.350786267992073 0.843206397010277 0.5708418688765182 0.06414676567608675 4.423207593332838 0.15185136108330458 0.3415015746032563 5.001685709814565e-06 5.3008836014463006 3.30458970777542 S(ph)LGSAGPSGTLPR ddPTM_PC-9_AZD4547_30min_R2 1 SLGSAGPSGTLPR 13 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 S(0.999)LGS(0.001)AGPSGTLPR 70.628 0.027767 5358300.0 22503.0 20768.0 35388.0 46488.0 42059.0 38804.0 34648.0 49434.0 30484.0 44981.0 True False 29658.485908522835 27480.849859624937 34918.731997891555 35770.9098324403 36219.83384118584 36377.57974574813 37731.60487793011 41795.1111803115 32095.32200568057 43406.228881150826 0.6832771856253572 0.6331084401473658 0.8044636195763837 0.8240962358278914 0.8344386226308252 0.8380727993061178 0.8692670579893449 0.962882799488279 0.739417425401311 1.0 15.405614466715384 -3.13634993670282 0.2666516004998365 0.9323733744512807 1.2317288375277324e-21 0.6013993920778133 0.06803903959261849 14.632411816219195 0.4296365250998396 0.08067961652567204 5.242221544543449 0.0007305501988421846 3.13634993670282 -0.9323733744512807 S(ph)LGSAGPSGTLPR ddPTM_PC-9_Lapatinib_30min_R1 2 SLGSAGPSGTLPR 13 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 S(1)LGSAGPSGTLPR;S(0.998)LGS(0.002)AGPSGTLPR 71.976 0.024656 14235200.0 70029.0 75152.0 63555.0 60408.0 70110.0 68063.0 58415.0 64690.0 69422.0 51689.0 True False 69030.37361825412 74977.99016132517 58329.75322939466 64850.60583518065 65986.26764156343 65152.10415260243 61439.442873209875 67695.73356245569 61602.9633139313 60623.37477873683 1.1386758633975946 1.236783508588557 0.9621660529834667 1.0697293918702542 1.0884624599405772 1.0747026933158135 1.0134612778891234 1.1166605918844266 1.016158594581212 1.0 15.887586545776406 -5.2515452642135685 24.995693980566386 1.0495371277700811 1.1877296908928896 0.5772835361680495 0.04937364205753558 473.58498540223985 1196420.9319224476 0.012002122689473666 0.03092776098709944 5.60344012632106e-06 5.2515452642135685 0.13819256312280848 S(ph)LGSTEGESESRPGK ddPTM_PC-9_AZD4547_30min_R2 1 SLGSTEGESESRPGK 15 1 H0Y8W3;O43566-4;O43566-5;O43566;O43566-6 H0Y8W3 RGS14 Regulator of G-protein signaling 14 1 S(0.821)LGS(0.144)T(0.036)EGESESRPGK 101.3 0.0008021 20161000.0 20184.0 14122.0 21526.0 40126.0 34457.0 26033.0 21382.0 27453.0 17673.0 24536.0 True False 26602.09214671931 18686.66032923841 21240.551175161458 30875.570640520087 29673.24032111416 24405.15239462585 23284.956577577406 23210.769657181107 18607.15869985542 23677.002108177163 1.1235414021242127 0.7892325322209912 0.8970963079749761 1.304032094073971 1.2532515808184228 1.0307534831952907 0.9834419269463021 0.980308636673431 0.7858747748064436 1.0 14.531198803528785 -7.668181041249313 1.970224142414207 0.9000427753793865 1.0631991110814858 0.16087396275337007 0.15111220740936995 0.7160869591935266 5.487900949709236 0.11235935992655693 0.050185820550742624 2.146935309922616e-08 7.668181041249313 0.1631563357020993 S(ph)LGSTEGESESRPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLGSTEGESESRPGK 15 1 H0Y8W3;O43566-4;O43566-5;O43566;O43566-6 H0Y8W3 RGS14 Regulator of G-protein signaling 14 1 S(0.9)LGS(0.082)T(0.017)EGESESRPGK;S(0.975)LGS(0.023)T(0.003)EGESESRPGK 74.141 0.0076915 15848200.0 40018.0 36038.0 37781.0 36899.0 44109.0 42898.0 37347.0 43058.0 38758.0 38510.0 True False 46792.257008472014 39615.61447315525 38681.84232524041 34831.66865817207 35466.15808910588 40648.353362386995 33809.22179113508 41927.7731237221 39324.76242706784 45491.55815500775 1.0285920928237338 0.8708344158749007 0.8503081427423537 0.7656732385267347 0.7796206489181715 0.8935361858541306 0.7431977088129995 0.9216605195376597 0.8644408769880515 1.0 15.473311229523146 -10.20759665816221 8.39798977669464 0.9999999999778971 0.852306539720681 0.22302324425101872 0.07923021959791374 0.0 0.0 0.07750330231842943 0.018797311730129274 6.200166351352188e-11 10.20759665816221 -0.14769346025721608 S(ph)LGSVQAPSYGAR ddPTM_PC-9_AZD4547_30min_R2 4 SLGSVQAPSYGAR 13 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.999)LGS(0.001)VQAPSYGAR;S(0.985)LGS(0.015)VQAPSYGAR;S(1)LGSVQAPSYGAR;S(0.929)LGS(0.07)VQAPSYGAR 194.77 1.2392e-06 357694900.0 45687.9 37925.4 59673.700000000004 59500.8 47612.5 55330.5 47613.4 73960.8 59403.6 69570.2 True False 60215.701832644554 50184.043878381126 58882.387747897104 45783.809838196175 41002.32622657364 51870.67508818979 51850.900360622174 62531.85781010598 62543.55302114705 67134.5684735207 0.896940327491565 0.7475142094370469 0.8770800064220502 0.6819707176080871 0.6107483396239574 0.7726373501402438 0.7723427965590226 0.9314405265711937 0.9316147320707893 1.0 16.034768199973428 -7.785182355472319 3.3432731987985607 0.9580995465922884 0.7583881142471238 0.5412382874450187 0.07985825613868502 0.20043594088470235 4.606340754628642 0.05034065792309692 0.023337566274669874 1.639901052216376e-08 7.785182355472319 -0.19971143234516453 S(ph)LGSVQAPSYGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLGSVQAPSYGAR 13 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.991)LGS(0.009)VQAPSYGAR;S(0.561)LGS(0.437)VQAPS(0.002)YGAR 124.81 0.00014916 9763100.0 15760.5 19833.0 16722.7 24877.0 24048.1 15372.0 17886.8 13903.0 15129.4 9289.0 True False 18428.44136593591 21801.88916826926 17121.43258919292 23483.222342322188 19336.047435730285 14565.865259140583 16192.432814782318 13538.060981446151 15350.638852987258 10973.022168316465 1.6794317083534418 1.98686276522981 1.5603206050771856 2.1400870227099067 1.7621442059564265 1.3274251191433935 1.4756584436269884 1.233758646777912 1.3989435742972192 1.0 13.421673304266596 -6.732130329883798 4.380804266652064 1.3093633323488845 1.8448627031917333 0.6727254460421221 0.18808194346451945 0.12224108900611483 5.312386461417492 0.06167455324451398 0.05908798744727375 1.8529754700956945e-07 6.732130329883798 0.5354993708428488 S(ph)LGSVQAPSYGAR ddPTM_PC-9_Lapatinib_30min_R1 5 SLGSVQAPSYGAR 13 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.997)LGS(0.003)VQAPSYGAR;S(0.8)LGS(0.2)VQAPSYGAR;S(0.999)LGS(0.001)VQAPSYGAR;S(0.961)LGS(0.039)VQAPSYGAR;S(0.81)LGS(0.184)VQAPS(0.005)YGAR 186.29 4.0983000000000004e-05 488738700.0 102457.6 155163.3 157222.4 133889.3 163456.7 123513.8 118900.0 142936.8 157292.1 98681.40000000001 True False 100996.53583557752 154804.02891205472 144296.1811680146 143735.9657636116 153842.4982742368 118231.40269873054 125056.060217832 149578.16554444304 139576.2073387573 115738.34850529986 0.8726281058948471 1.337534455185059 1.2467447741524238 1.241904413013373 1.3292266587611805 1.021540433448612 1.0805066931822123 1.2923820624379618 1.2059633573600357 1.0 16.820507437687233 -6.760435218937282 24.999966272968404 1.135879167038312 1.2172388059409904 0.07188922880247284 0.14534629210062594 84.2139124663341 2096653.1518114875 0.04941700074560685 0.04676519790514996 1.7360602010852662e-07 6.760435218937282 0.0813596389026785 S(ph)LGVSVR ddPTM_PC-9_AZD4547_30min_R2 1 SLGVSVR 7 0 Q9BRP0 Q9BRP0 OVOL2 Transcription factor Ovo-like 2 1 S(1)LGVSVR 88.177 0.017446 2203600.0 5721.2 6303.6 8706.0 14353.0 9173.0 8444.2 7873.4 8350.7 6763.9 10378.0 True False 7540.422591647377 8341.115426383461 8590.552751600651 11044.137601639468 7899.487287505598 7916.182839115727 8574.117347203151 7060.291194995902 7121.425945224466 10014.669378817356 0.7529377462621571 0.8328897451199206 0.8577969403334531 1.102796026896265 0.7887916204417382 0.7904587300565041 0.8561558073338692 0.7049949357219478 0.7110994557930622 1.0 13.289827172800514 S(ph)LGVSVR ddPTM_PC-9_Lapatinib_30min_R1 1 SLGVSVR 7 0 Q9BRP0 Q9BRP0 OVOL2 Transcription factor Ovo-like 2 1 S(1)LGVSVR 90.601 0.018039 0.0 6781.4 8467.5 8473.9 5872.2 8813.8 7738.0 9036.8 9452.1 9396.7 6678.2 True False 6684.695992443547 8447.894023991646 7777.20865219994 6304.061177084948 8295.389612597512 7407.063778159016 9504.681286598003 9891.279072587526 8338.344694362282 7832.517971857848 0.8534542807895987 1.0785668228716279 0.9929385007660839 0.8048575438620595 1.0590961479313237 0.9456810446873554 1.213489879084634 1.2628479255492018 1.0645803462337224 1.0 12.93526045955276 -7.2539797614545325 24.788812753295176 1.1571335327812262 0.9608746302631676 0.40999750738351903 0.10404178783737505 464.7348708989501 1544349.5646118687 0.03940047162639712 0.02991576922223339 5.5721171493504184e-08 7.2539797614545325 -0.19625890251805866 S(ph)LHFPATTQSK ddPTM_PC-9_AZD4547_30min_R2 2 SLHFPATTQSK 11 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5;A0A087WZJ0 Q8NEV8-2 EXPH5 Exophilin-5 1 S(1)LHFPATTQSK;S(1)LHFPATTQSK 115.24 0.00078145 45846000.0 220987.0 189071.0 280214.0 396358.0 322288.0 301507.0 271689.0 338853.0 286939.0 308506.0 True False 291256.26918485254 250184.5032650785 276498.17927142465 304983.786770056 277543.87429582555 282653.7196268751 295868.79466866615 286491.05491730536 302106.00974242133 297705.29884191765 0.978337538222692 0.8403763864408983 0.928764722519252 1.02444863412392 0.9322772398592815 0.9494413459431403 0.9938311337406638 0.9623310570277518 1.0147821047110097 1.0 18.1835253746991 -5.941781663641305 0.40825712747758613 0.9994895463293909 0.890715454218258 0.25726247367165156 0.04423589159218768 3.1296546424604657 0.7996542941200904 0.04198286411232906 0.1526345300630085 1.143453047662144e-06 5.941781663641305 -0.10877409211113287 S(ph)LHFPATTQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLHFPATTQSK 11 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5;A0A087WZJ0 Q8NEV8-2 EXPH5 Exophilin-5 1 S(1)LHFPATTQSK;S(1)LHFPATTQSK;S(1)LHFPATTQSK;S(0.999)LHFPAT(0.001)TQSK 116.98 0.0012073000000000001 52017000.0 376482.0 356467.0 411893.0 444942.0 494722.0 474930.0 467801.0 470636.0 483770.0 371111.0 True False 440212.96674155537 391854.6879516684 421714.09123290126 420013.34226142755 397784.77549159236 450023.83473351813 423487.5026940523 458282.3036800623 490844.2210470765 438390.4865869406 1.0041572073536622 0.8938485207615395 0.9619599515402986 0.9580804217067139 0.9073754738350249 1.026536497717248 0.9660052297007755 1.045374655020432 1.1196507133822884 1.0 18.7418569654753 -7.52010074238112 1.3456816981794797 1.0640898055451473 0.9480743308435982 0.465286780014619 0.046210047073478255 0.3612415654391185 1.2411827804754993 0.032047222178699104 0.0149655119496565 3.0192512697724055e-08 7.52010074238112 -0.11601547470154916 S(ph)LHFPATTQSK ddPTM_PC-9_Lapatinib_30min_R1 6 SLHFPATTQSK 11 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5;A0A087WZJ0 Q8NEV8-2 EXPH5 Exophilin-5 1 S(1)LHFPATTQSK;S(0.999)LHFPAT(0.001)TQSK;S(1)LHFPATTQSK;S(1)LHFPATTQSK;S(1)LHFPATTQSK;S(0.999)LHFPATTQSK 122.46 0.00066711 53040000.0 506412.0 410130.0 488957.0 362120.0 413585.0 446346.0 361088.0 405830.0 469608.0 294376.0 True False 499190.4720154126 409180.36918331304 448756.84288860275 388751.51279690705 389258.7434393948 427256.82206334523 379783.3698228472 424686.3433552533 416715.80184852966 345258.4993686358 1.4458455705747075 1.1851420600262392 1.2997705884409256 1.1259723178656156 1.1274414508295116 1.2374983464408764 1.0999971630455037 1.2300532619236453 1.2069675405835505 1.0 18.397317404766774 -1.5228800037675836 0.9244345235841571 1.1628652674829925 160.07329596708024 0.5277350026531474 0.07941652897469988 822.4527835129012 1.6230317981982292 0.02478332672507646 276053.0875830688 0.029999913066906785 1.5228800037675836 158.91043069959724 S(ph)LHGPCPVTTFGPK ddPTM_PC-9_AZD4547_30min_R2 2 SLHGPCPVTTFGPK 14 0 O95544;O95544-2 O95544 NADK NAD kinase 1 S(1)LHGPCPVTTFGPK;S(1)LHGPCPVTTFGPK 155.09 0.00031552 11601800.0 33857.0 30270.0 46608.0 66001.0 58646.0 46317.0 42543.0 54422.0 41381.0 44308.0 True False 44622.82173065181 40054.185537887446 45989.94746687377 50785.489155285046 50504.01520364691 43420.79066807075 46329.24458328853 46012.33039314872 43568.315179014135 42756.79040630559 1.0436429233020967 0.9367912127468863 1.0756173938652647 1.1877759923671778 1.1811928520293888 1.0155297031291488 1.0835529080418553 1.0761408879363175 1.0189800208340443 1.0 15.383865938905847 -5.382611851193442 6.975961983381602 1.088592710566328 0.9909841329190133 0.22600128809887443 0.06509410820190142 0.32401968688358534 16.97830854431102 0.017736108087790633 0.037228018236367615 4.143698506274908e-06 5.382611851193442 -0.09760857764731468 S(ph)LHGPCPVTTFGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLHGPCPVTTFGPK 14 0 O95544;O95544-2 O95544 NADK NAD kinase 1 S(1)LHGPCPVTTFGPK;S(1)LHGPCPVTTFGPK;S(1)LHGPCPVTTFGPK;S(1)LHGPCPVTTFGPK 151.56 2.3559e-08 17873500.0 155429.0 148445.5 162754.0 153331.0 203327.0 166977.8 164269.2 175961.0 156302.1 131086.4 True False 181740.05983731823 163182.18819786777 166634.67260798256 144740.36117580917 163486.5339450822 158221.190220383 148708.4321699823 171342.21019609022 158587.72251797782 154851.3266406283 1.1736422527337596 1.0537990970950695 1.0760945755066116 0.9347053352130189 1.0557645032289202 1.0217619290248336 0.9603303723389974 1.1064949452692334 1.0241289239066111 1.0 17.240524217343847 -4.395434860519801 1.3560230294871993 1.0209373370068124 1.3993057131549023 0.47878608955884683 0.047691327793998595 2.8453260071418613 2.334783706271177 0.013535819147415447 1.9078454730401913 4.023139942260908e-05 4.395434860519801 0.3783683761480898 S(ph)LHGPCPVTTFGPK ddPTM_PC-9_Lapatinib_30min_R1 2 SLHGPCPVTTFGPK 14 0 O95544;O95544-2 O95544 NADK NAD kinase 1 S(1)LHGPCPVTTFGPK;S(1)LHGPCPVTTFGPK 146.0 3.5499e-05 11172000.0 34712.0 25840.0 27896.0 30156.0 32635.0 34945.0 28310.0 24423.2 38014.0 32020.0 True False 34217.00051459882 25780.16906760488 25602.498561674012 32373.772837466997 30715.47346287863 33450.48381077368 29775.753278106138 25557.991033275117 33732.46301483369 37554.61433603188 0.911126398701137 0.6864714103286642 0.6817404203006187 0.862045141717935 0.817888134545655 0.8907156790764729 0.7928653723262366 0.6805552788956064 0.8982241892567907 1.0 15.196702562141612 -8.521649801632243 21.597318026958163 1.0000000027321447 0.7900227609416929 0.4108202403572825 0.0807514797543269 15.4494762513018 271489.77456941735 0.07972310470527363 0.02058441711554543 3.0085012645151512e-09 8.521649801632243 -0.20997724179045185 S(ph)LHLDK ddPTM_PC-9_Lapatinib_30min_R1 1 SLHLDK 6 0 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 S(1)LHLDK 66.351 0.043923000000000004 2503300.0 38867.0 29940.0 41944.0 33714.0 30432.0 31792.0 30427.0 28666.0 31414.0 22095.0 True False 38312.74945266516 29870.675769508132 38495.52622852221 36193.44002660709 28642.049591614003 30432.330270771698 32002.361179545594 29997.927010377996 27875.82451591479 25914.09131026312 1.478452359913219 1.152680810292508 1.4855055408898823 1.3966702360222407 1.1052693011184418 1.174354520342342 1.2349405115691343 1.1575913139774072 1.075701408247903 1.0 14.661449185382361 -6.913634086816366 0.307377306359225 0.9870740341852493 1.4556835901734482 0.5566400908547797 0.10762284430534376 1.7999187488667574 0.3838963096288659 0.15518822002582303 0.30161945807080814 1.2200170868226872e-07 6.913634086816366 0.46860955598819887 S(ph)LIAQDHR ddPTM_PC-9_AZD4547_30min_R2 2 SLIAQDHR 8 0 E9PB39;H0YAN8;O15013-7;O15013-4;O15013-5;O15013-6;O15013 E9PB39 ARHGEF10 Rho guanine nucleotide exchange factor 10 1 S(1)LIAQDHR;S(1)LIAQDHR 92.611 0.0044459 14840200.0 24574.0 26171.0 39809.0 49506.0 34538.0 42766.0 46663.0 65995.0 50244.0 42896.0 True False 32388.020829046814 34630.26394820129 39281.10664926148 38093.156560075455 29742.994869275924 40091.835259423366 50815.916601790945 55796.98916423219 52899.79526484105 41394.224096526224 0.7824285038782692 0.8365965229218402 0.9489513937418608 0.920252943290999 0.718530073179266 0.9685369428820347 1.2276088684086577 1.3479414189313101 1.2779511252943225 1.0 15.337141856244326 -7.165007957207986 3.4267707293008316 1.2450527774433466 0.8510002380394416 0.7327046112438382 0.10510136366626956 0.12112422213941478 2.6828420634610817 0.04267433157490129 0.03175011344976295 6.83899116665468e-08 7.165007957207986 -0.39405253940390506 S(ph)LIAQDHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLIAQDHR 8 0 E9PB39;H0YAN8;O15013-7;O15013-4;O15013-5;O15013-6;O15013 E9PB39 ARHGEF10 Rho guanine nucleotide exchange factor 10 1 S(1)LIAQDHR;S(1)LIAQDHR 96.756 0.0034131 9123800.0 28868.0 30222.0 35840.0 32228.0 42741.0 38679.0 39948.0 46608.0 39412.0 25671.0 True False 33754.78223101031 33222.24042976017 36694.56152395692 30422.36964458573 34366.207868835736 36650.605149512 36163.8362415258 45384.58938525799 39988.325939821356 30324.949088475827 1.113102684279127 1.0955415071870764 1.2100452804354977 1.0032125546468575 1.1332651464168717 1.2085957685396433 1.1925440051363148 1.496608922667744 1.318660942287215 1.0 14.888217602805701 -7.128536324336448 1.9329847037797427 1.300264985227548 1.1109005831082155 0.19566396531220231 0.12642421545145907 0.428336816673169 3.1528429238712987 0.05880736088455832 0.041230820578035794 7.438128478916945e-08 7.128536324336448 -0.1893644021193326 S(ph)LIAQDHR ddPTM_PC-9_Lapatinib_30min_R1 2 SLIAQDHR 8 0 E9PB39;H0YAN8;O15013-7;O15013-4;O15013-5;O15013-6;O15013 E9PB39 ARHGEF10 Rho guanine nucleotide exchange factor 10 1 S(1)LIAQDHR;S(1)LIAQDHR 95.477 0.0036353 11841100.0 19691.6 20899.2 26217.3 27281.8 37643.0 30876.2 40668.0 25510.1 35104.1 28159.9 True False 19410.79417300282 20850.80918644303 24061.814795704628 29288.19458141689 35428.91274898547 29555.696901937637 42773.59004994774 26695.39237519863 31150.30659543914 33027.301194291824 0.5877196583158187 0.6313204056178444 0.7285431726363182 0.8867874007967332 1.0727159491647693 0.8948868309907747 1.2950979493698502 0.8082825847063898 0.9431683930875621 1.0 15.011371465046734 -5.722473574550325 1.8057639251020312 1.0034179959492808 0.6050584779466983 0.6377014975388671 0.12086606224397124 0.22374064675025046 1.4807480161831652 0.03728190522379655 0.08049570083147661 1.8946387936452126e-06 5.722473574550325 -0.3983595180025825 S(ph)LIMEAPRGVQVSAAAGDFKAT(ph)CRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLIMEAPRGVQVSAAAGDFKATCRK 25 3 Q08AT0;Q96LD1;Q96LD1-2 Q08AT0 SGCZ Zeta-sarcoglycan 2 S(0.995)LIMEAPRGVQVS(0.005)AAAGDFKAT(1)CRK 52.09 0.0061293 15284000.0 18014.0 25393.0 80924.0 68708.0 97171.0 107620.0 92696.0 84680.0 102830.0 82972.0 True False 21063.414407282085 27913.849223509376 82853.53506597907 64858.51351434141 78131.04009786007 101976.21774581763 83915.16381907652 82457.23972587625 104333.69421475253 98014.16679400952 0.21490173406819646 0.28479402658366965 0.8453220363552889 0.6617259079562513 0.7971402773036206 1.040423247795749 0.8561534170405792 0.8412787908422633 1.064475653137208 1.0 16.580702668433716 -5.148088306371925 0.9008659458015844 0.9310653989448295 7.186189644844191e-22 0.8324555275271105 0.11476065045172561 0.5383994501074735 0.49901169057147693 0.04232872001393239 0.4410826693875342 7.110689152230621e-06 5.148088306371925 -0.9310653989448295 down S(ph)LIVEGK ddPTM_PC-9_AZD4547_30min_R2 4 SLIVEGK 7 0 H0Y8X0;B4DFG0;H0Y993;P35659;D6R9L5;A0A494C198;A0A494C028 H0Y8X0 DEK Protein DEK 1 S(1)LIVEGK;S(1)LIVEGK;S(1)LIVEGK;S(1)LIVEGK 94.69200000000001 0.013366 55372200.0 232709.0 286881.0 265666.0 162837.0 222232.0 342217.0 318109.0 352395.0 310899.0 248971.0 True False 306705.6213521067 379609.6729862799 262143.09525691913 125297.445456571 191378.9228035474 320818.11689131847 346420.08474121045 297940.44998150814 327332.48642711213 240254.6010708745 1.276585838460714 1.5800308143705268 1.0911054110451255 0.521519441867457 0.796567149809094 1.3353255898590592 1.4418874110927742 1.240102993464073 1.3624400322329306 1.0 17.874204534482963 -6.8147287607226685 24.992167961099792 1.3013291669761562 1.0550026165968567 0.13171756827066694 0.28224910226096434 214.27665112774233 100491.76996817518 0.11260098886905792 0.09930482123272531 1.532044003351981e-07 6.8147287607226685 -0.2463265503792995 S(ph)LIVEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLIVEGK 7 0 H0Y8X0;B4DFG0;H0Y993;P35659;D6R9L5;A0A494C198;A0A494C028 H0Y8X0 DEK Protein DEK 1 S(1)LIVEGK;S(1)LIVEGK;S(1)LIVEGK;S(1)LIVEGK 98.044 0.012289 46765900.0 239164.0 454890.0 365074.0 255271.0 318651.0 217032.0 314620.0 147568.0 208471.0 210146.0 True False 279649.7414956816 500048.47293672105 373778.7487108558 240968.99346974818 256213.62400534286 205650.45985699957 284816.91594845406 143694.49636122014 211519.49398661582 248243.8062851796 1.1265124624073126 2.0143442062851356 1.5056921431564867 0.970694886916638 1.0321047998716537 0.8284213126379102 1.1473273803305275 0.5788442358805342 0.8520635304134222 1.0 17.921398197213108 -5.7505436495649604 3.9419466348867718 0.9024923611055332 1.6134093882017262 0.5850746829073324 0.2445554637819349 0.13382152317167806 4.58786366915617 0.06667656178717837 0.11311905605207401 1.776054753670934e-06 5.7505436495649604 0.710917027096193 S(ph)LIVEGK ddPTM_PC-9_Lapatinib_30min_R1 2 SLIVEGK 7 0 H0Y8X0;B4DFG0;H0Y993;P35659;D6R9L5;A0A494C198;A0A494C028 H0Y8X0 DEK Protein DEK 1 S(1)LIVEGK;S(1)LIVEGK 89.029 0.016874 53275000.0 96256.0 168040.0 142284.0 124667.0 151206.0 153181.0 159442.0 148494.0 126929.0 97638.0 True False 94883.37178881126 167650.9137043466 130585.95875212285 133835.42705692045 142312.36036243374 146629.8057123515 167697.12660430235 155393.5733439987 112632.91939837496 114514.59820554279 0.8285700973993259 1.4640134649333458 1.1403433343732605 1.1687193524156512 1.2427442666043034 1.2804464060482923 1.464417019595196 1.3569761041739155 0.9835682189288182 1.0 16.805171997792073 -4.74174812030177 24.97840967226313 1.2486665774620598 0.8285686379277586 0.3624022560316654 0.15998008450815435 1503.4623672741113 1907045.9200990838 0.03887642132942688 1.50862616419258 1.8123909282719746e-05 4.74174812030177 -0.4200979395343012 S(ph)LIYTDTLVR ddPTM_PC-9_AZD4547_30min_R2 2 SLIYTDTLVR 10 0 Q5SYE7-2 Q5SYE7-2 NHSL1 NHS-like protein 1 1 S(1)LIYTDTLVR;S(1)LIYTDTLVR 188.27 0.00027957 28297000.0 52092.0 36583.0 47415.0 78734.0 54651.0 63357.0 35528.0 72206.0 49372.0 52710.0 True False 68656.17241908953 48407.73933044387 46786.24611958938 60583.09272817394 47063.65199492731 59395.276774336795 38689.923173144234 61048.22182881368 51981.703125064334 50864.638943675374 1.3497819672939289 0.9516972957194852 0.9198187009918192 1.1910650303693344 0.925272507036626 1.1677125407320352 0.7606448011159043 1.2002094794463207 1.0219615081240612 1.0 15.63437542387866 -4.7543852912836515 24.99870355792724 1.018120890902415 1.3497825406197814 0.3652642464344057 0.13220322001832258 262.800190777475 931246.498368252 0.03073195920205919 0.3008437216623659 1.7604135744184674e-05 4.7543852912836515 0.33166164971736634 S(ph)LIYTDTLVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLIYTDTLVR 10 0 Q5SYE7-2 Q5SYE7-2 NHSL1 NHS-like protein 1 1 S(1)LIYTDTLVR;S(0.987)LIY(0.002)T(0.007)DT(0.003)LVR;S(0.998)LIYT(0.002)DTLVR 137.4 0.00011719 21972900.0 37364.0 24395.0 35234.9 32438.7 41536.0 30657.3 29847.899999999998 30792.8 29706.2 23257.2 True False 43688.98722736141 26816.774379061608 36075.033645102376 30621.26480668438 33397.31896867085 29049.57721890778 27020.490831917443 29984.521627668484 30140.596976391003 27473.546256106103 1.5902201637930655 0.9760943901845752 1.313082530693851 1.1145727064586242 1.215617330844145 1.0573653997234302 0.9835093940925822 1.0913961142167552 1.0970770462401496 1.0 14.745755523523071 -4.752098121112266 24.998543702722035 1.1038027562008805 1.5902211165870008 0.6873144432787888 0.10016342334984614 219.34330592285386 586952.3236793122 0.024915568106901365 0.30755958830977237 1.769709078862324e-05 4.752098121112266 0.4864183603861203 S(ph)LIYTDTLVR ddPTM_PC-9_Lapatinib_30min_R1 2 SLIYTDTLVR 10 0 Q5SYE7-2 Q5SYE7-2 NHSL1 NHS-like protein 1 1 S(1)LIYTDTLVR;S(0.966)LIYT(0.031)DT(0.002)LVR 158.06 0.00040998 20563400.0 37259.0 27497.7 24855.0 26548.4 28702.0 27072.0 25842.1 22387.2 31167.0 20635.8 True False 36727.67982753624 27434.030765103646 22811.517843074547 28500.857898866212 27013.80479030313 25914.193667914304 27180.077491633594 23427.391040491675 27656.6442569401 24202.670534524907 1.517505259394599 1.1335125487895739 0.9425206945875707 1.1775914504232075 1.1161497551176496 1.070716292689599 1.1230197697754651 0.967967192177107 1.142710438399272 1.0 14.56287862351005 -4.773430789890014 4.171842724517396 1.0721251907012237 1.5567524196704259 0.7699113346930252 0.0732953653846947 0.09639124057491906 3.3327212146194833 0.01757393846931616 0.1411534160313206 1.6848809116544407e-05 4.773430789890014 0.4846272289692022 S(ph)LKSPIQSDLDAFHSGFQTCAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLKSPIQSDLDAFHSGFQTCAK 22 1 Q9C0J9 Q9C0J9 BHLHE41 Class E basic helix-loop-helix protein 41 1 S(0.521)LKS(0.45)PIQS(0.028)DLDAFHSGFQTCAK 73.405 0.00047412 3818600.0 24118.0 28216.0 26156.0 34814.0 40048.0 30537.0 32046.0 26257.0 26216.0 26422.0 True False 28200.701047786704 31017.098006952336 26779.658237182386 32863.48444851085 32200.881886973464 28935.585962683857 29010.370887051562 25567.781571591127 26599.359404200695 31212.099443563082 0.9035182365344725 0.9937523767997939 0.8579896487131433 1.0529084885152875 1.0316794596018213 0.9270631094522956 0.9294591329720505 0.8191625051631702 0.8522130801324972 1.0 14.929817781181729 -7.349370170317915 2.5931735366197364 0.8781565449127162 0.9668643978740816 0.15461446682254953 0.07013293083484311 0.43511228235240446 5.71159103279553 0.03401820232053547 0.02127032914789119 4.4733185892858486e-08 7.349370170317915 0.08870785296136541 S(ph)LLAIHLHLVPAS(ph)S(ph)AAMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLLAIHLHLVPASSAAMK 18 0 Q86UQ8 Q86UQ8 NFE4 Transcription factor NF-E4 3 S(1)LLAIHLHLVPAS(1)S(1)AAMK 43.913999999999994 0.044019 7593500.0 11982.0 17895.0 23159.0 20199.0 24721.0 21809.0 17425.0 15868.0 20819.0 11830.0 True False 14010.315944712662 19671.497336065073 23711.198390996604 19067.315516041566 19877.09751118335 20665.297647449708 15774.377853924787 15451.481813535753 21123.438489321554 13974.685353771525 1.0025496524636615 1.407652253920413 1.696725027486745 1.364418234353708 1.422364583387122 1.4787665785886552 1.1287823270859945 1.1056765445789207 1.5115502034269919 1.0 13.770528180065948 -7.261886964223077 24.99691574771498 1.1953086447990648 1.4094813235288117 0.2028570108905392 0.2014240934622731 69.09237794802488 3858545.319247246 0.081221177073148 0.0585743466680574 5.471583557272334e-08 7.261886964223077 0.21417267872974688 S(ph)LLDASEEAIKK ddPTM_PC-9_AZD4547_30min_R2 2 SLLDASEEAIKK 12 1 P18206;P18206-2 P18206 VCL Vinculin 1 S(1)LLDASEEAIKK;S(0.995)LLDAS(0.005)EEAIKK 92.939 0.0025618999999999998 13822400.0 26660.7 28073.1 31726.0 26314.0 31325.6 36742.0 38339.0 38878.0 41799.0 34264.0 True False 35138.24802299048 37147.18057560847 31305.292510599847 20247.713847247313 26976.58115921566 34444.51693171523 41751.096727515665 32870.29842756302 44008.40980565021 33064.427789149915 1.0627205844016177 1.1234787068596515 0.9467967421130654 0.6123715183086155 0.8158792685372895 1.041739392901824 1.2627194698108848 0.994128754841159 1.3309896087205708 1.0 15.012992314152807 -6.9843701951083315 6.726074698517031 1.1476529576576928 0.9103710908436716 0.3210407150778293 0.161232443395115 0.20010840375252614 39.70803547186841 0.06254337223929156 0.0536991177457257 1.0366443974677741e-07 6.9843701951083315 -0.2372818668140212 S(ph)LLDASEEAIKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLLDASEEAIKK 12 1 P18206;P18206-2 P18206 VCL Vinculin 1 S(0.999)LLDAS(0.001)EEAIKK;S(1)LLDASEEAIKK;S(1)LLDASEEAIKK 121.18 0.00021021 16661600.0 57363.2 85724.0 59940.0 65558.0 69229.0 45679.2 60201.0 47311.8 40896.9 44721.5 True False 67073.65678515616 94234.11218982052 61369.19692371588 61884.99780190365 55664.07441453477 43283.702338364215 54498.325462503606 46069.91538099577 41494.93979316659 52829.15393480079 1.2696333707697696 1.783752060578516 1.1616539799114483 1.1714175449086153 1.0536620458323582 0.8193146986942643 1.031595651328485 0.8720547642662053 0.7854553159109392 1.0 15.689046684691643 -5.80904280037374 1.1877406740236436 0.9053988918802198 1.530071705146241 0.6738102243871431 0.15656025500520498 0.27655649738247107 0.7726206969609416 0.05424334045361373 0.1353596723607901 1.552234027424166e-06 5.80904280037374 0.6246728132660211 S(ph)LLDASEEAIKK ddPTM_PC-9_Lapatinib_30min_R1 2 SLLDASEEAIKK 12 1 P18206;P18206-2 P18206 VCL Vinculin 1 S(1)LLDASEEAIKK;S(0.998)LLDAS(0.002)EEAIKK 109.95 0.0005733 19696800.0 27916.0 47720.0 46179.0 49421.0 51156.0 48817.0 54741.0 48603.0 48677.0 41763.0 True False 27517.912720832574 47609.507271908085 42382.34087609496 53055.585203623064 48147.104656565636 46729.21070798508 57575.221130229904 50861.272813974865 43194.48366846579 48981.67890430048 0.5618001125399678 0.9719860228745257 0.8652692562641802 1.0831720429036764 0.9829615018022264 0.9540140671634341 1.1754440112744875 1.0383734071946922 0.8818497984288859 1.0 15.579954604357772 -4.448381844444616 1.615493267754611 1.009880085427454 2.0963134279479276e-20 0.6853403423083362 0.08743487761525431 1.5420903000995816 1.9370291288494135 0.024169862338585476 3.1799679771132134 3.561378688723164e-05 4.448381844444616 -1.009880085427454 S(ph)LLGIDTEDAIQGR ddPTM_PC-9_AZD4547_30min_R2 2 SLLGIDTEDAIQGR 14 0 P49454 P49454 CENPF Centromere protein F 1 S(1)LLGIDTEDAIQGR;S(1)LLGIDTEDAIQGR 225.31 2.0692e-20 15758600.0 18444.5 16367.6 20498.4 27897.0 18975.7 21463.7 21988.0 29154.0 20159.5 23886.0 True False 24309.467330567 21658.106614136985 20226.577822583364 21465.777654353526 16341.251599424386 20121.5714459544 23944.88940359985 24648.919192272555 21225.090013565055 23049.75841033255 1.0546517190249491 0.9396240181167483 0.8775179966101668 0.9312799410830713 0.7089554392942821 0.8729623576850364 1.038834723441875 1.06937863527555 0.9208378515607544 1.0 14.49246400907427 -7.259351401805093 24.94502843707656 1.0130443580145536 0.8914705344529953 0.2708623889185068 0.08768781202407491 244.30736183959974 2918753.7249993444 0.036729559820570044 0.027026776480484963 5.503622002220514e-08 7.259351401805093 -0.12157382356155833 S(ph)LLGIDTEDAIQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLLGIDTEDAIQGR 14 0 P49454 P49454 CENPF Centromere protein F 1 S(1)LLGIDTEDAIQGR;S(1)LLGIDTEDAIQGR;S(1)LLGIDTEDAIQGR;S(1)LLGIDTEDAIQGR 209.56 4.325e-11 14101600.0 31153.7 31191.7 33380.4 31626.2 35597.3 36501.3 35630.3 28166.9 27740.300000000003 19195.4 True False 36427.406096377505 34288.205837236135 34176.31533187196 29854.286547523818 28622.264602356176 34587.107571133754 32255.1400429668 27427.54872029747 28145.949408008386 22675.37406929721 1.606474318132672 1.512134076926337 1.5071996266710854 1.3165951069335151 1.2622620696304694 1.525315854346377 1.422474440527124 1.2095742560399378 1.2412562333919075 1.0 14.468838730235712 -7.444108656118044 0.05111724686039372 1.0963779018651964e-12 2.651840027806994 0.7443525770510738 0.08967494754514942 28.513024907109706 1.0572285322490715 25.337540550361027 28.469413243542753 3.5965934074312594e-08 7.444108656118044 2.6518400278058976 S(ph)LLGIDTEDAIQGR ddPTM_PC-9_Lapatinib_30min_R1 1 SLLGIDTEDAIQGR 14 0 P49454 P49454 CENPF Centromere protein F 1 S(1)LLGIDTEDAIQGR 179.55 5.8178000000000004e-05 7499500.0 13673.0 14815.0 12202.0 9876.7 12201.0 11351.0 9066.4 9018.3 12802.0 13948.0 True False 13478.020512678893 14780.696777730895 11198.798661082103 10603.065465705342 11483.361168088932 10865.544190473382 9535.813829764093 9437.323140922765 11360.103948963562 16358.893215458238 0.8238956227150452 0.903526698478841 0.6845694579447382 0.6481529848049891 0.7019644310189517 0.6641980021121509 0.5829131411380131 0.5768925205774327 0.694429861442515 1.0 13.997787523514697 -5.273812825802767 19.500718820323048 0.6726241358426492 0.8637110828444929 0.24593556166265618 0.11388897739730627 39.98095037759571 63013.89367941281 0.0278832237914667 0.059233678607937365 5.323376391135864e-06 5.273812825802767 0.1910869470018437 S(ph)LLRPGQAAELR ddPTM_PC-9_AZD4547_30min_R2 3 SLLRPGQAAELR 12 1 Q96BY6;Q96BY6-2;F8WB48;F8WE73 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 S(1)LLRPGQAAELR;S(1)LLRPGQAAELR;S(1)LLRPGQAAELR 59.84 0.029467 18731000.0 25787.5 23858.5 30481.4 34760.4 55938.0 39818.0 33156.7 50261.0 33853.6 30004.0 True False 33987.38858667879 31570.293546603487 30077.196719807034 26746.926822826474 48171.9742601644 37328.17416545199 36107.582066961 42494.317332880935 35643.03218250582 28953.569092506834 1.1738583411975523 1.090376576571137 1.0388079142751003 0.9237868650103161 1.6637663600730759 1.2892425816723403 1.2470857030301532 1.467671125349394 1.231041052957102 1.0 14.82145357904834 -6.231142315065801 24.99979762376321 1.3350211109624082 1.0578338309294086 0.35426745357981826 0.17070448060163604 720.9612692175125 594905.288768249 0.04840681736636132 0.06248503397331041 5.872968681858879e-07 6.231142315065801 -0.27718728003299953 S(ph)LLRPGQAAELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLLRPGQAAELR 12 1 Q96BY6;Q96BY6-2;F8WB48;F8WE73 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 S(1)LLRPGQAAELR;S(1)LLRPGQAAELR;S(1)LLRPGQAAELR 63.727 0.021859 24239500.0 47332.0 44417.0 39994.7 35184.0 40699.7 27606.3 19429.6 35388.4 22788.4 14487.2 True False 55344.37275038727 48826.42621827335 40948.325328744366 33212.75454806707 32724.885950241063 26158.57702988633 17589.087629877595 34459.491997109195 23121.637238582814 17113.614679387898 3.233938229136685 2.8530750009862746 2.3927338610739928 1.9407211842901553 1.9122135541391967 1.528524366123098 1.0277833151790177 2.0135718048281843 1.3510668360688955 1.0 14.06285689269378 -1.5228787452805672 0.283344111676776 1.1711051019158347 18.37411585114599 0.864738449345489 0.25872651479501696 18.1984290375782 0.25715967011121427 0.29037222491582687 155.61598811691405 0.029999999999984137 1.5228787452805672 17.203010749230156 up S(ph)LLRPGQAAELR ddPTM_PC-9_Lapatinib_30min_R1 4 SLLRPGQAAELR 12 1 Q96BY6;Q96BY6-2;F8WB48;F8WE73 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 S(1)LLRPGQAAELR;S(1)LLRPGQAAELR;S(1)LLRPGQAAELR;S(1)LLRPGQAAELR 78.985 0.007491299999999999 27276700.0 56059.0 45863.0 45549.0 61207.0 37700.2 25178.1 22972.300000000003 29198.300000000003 41778.6 31354.699999999997 True False 55259.58838003843 45756.807041314314 41804.13704422463 65708.36696056648 35482.74835744497 24101.291356017784 24161.693289672832 30554.95961163471 37073.05411983821 36774.318117488416 1.5026679272064911 1.2442598363109874 1.1367753145188635 1.7868004173629577 0.9648784851450658 0.6553837729639957 0.6570262761223704 0.8308776661477776 1.0081234953533436 1.0 15.166410970311992 -6.476773225808523 9.334081582446283 0.8088869947324939 1.384718455336056 0.6707348691125836 0.19497000211350426 0.2913371738971909 57.28790192960701 0.06093028311703364 0.0686824766700503 3.336005624541298e-07 6.476773225808523 0.5758314606035622 S(ph)LLSGR ddPTM_PC-9_AZD4547_30min_R2 1 SLLSGR 6 0 Q14126 Q14126;REV__Q5VTT5 DSG2 Desmoglein-2 1 S(1)LLSGR 90.37 0.045333 0.0 6581.4 13306.0 16740.0 17553.0 21849.0 17167.0 19399.0 21516.0 15336.0 18385.0 True False 8674.148298375869 17606.904286988112 16518.016662278314 13506.427041146631 18815.643491192604 16093.544776189534 21125.47341915742 18191.196588493396 16146.629650935483 17741.346745958483 0.4889227645782786 0.9924220826696262 0.9310463798945339 0.7612966047362456 1.060553280459323 0.9071208069283511 1.1907480148861782 1.025356014341887 0.9101129627948746 1.0 14.114827908352424 -4.760221482075374 24.99983112135404 0.9753778256432195 0.48892218162747175 0.6518773319285445 0.10665286680707427 19.74770583160981 405195.7140174097 0.0274231331772381 0.1649247674368444 1.736914808725969e-05 4.760221482075374 -0.48645564401574776 S(ph)LLSGR ddPTM_PC-9_Lapatinib_30min_R1 1 SLLSGR 6 0 Q14126 Q14126;REV__Q5VTT5 DSG2 Desmoglein-2 1 S(1)LLSGR 87.696 0.041669 0.0 23157.0 25088.0 16276.0 14081.0 17683.0 12548.0 10326.0 11800.0 15707.0 8961.6 True False 22826.7769335263 25029.910277402112 14937.850107176888 15116.563712839008 16642.920706115616 12011.351290816656 10860.629754493968 12348.271078017882 13937.912257957394 10510.600619418603 2.1717861576200743 2.3813967615855094 1.4212175543592465 1.4382207316402804 1.5834414519915632 1.142784482613237 1.0333024864848044 1.1748397189789646 1.3260814260420803 1.0 13.35955749279799 -5.2285448698722465 0.7766718448902936 1.1580266129340708 2.668926585873067 0.8069055680915547 0.1948314442549665 0.6574592699479169 0.46292314966073095 0.08319091421105006 0.7718919092370269 5.90819920857464e-06 5.2285448698722465 1.510899972938996 up S(ph)LMPHYQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLMPHYQR 8 0 Q96JM2;Q96JM2-3 Q96JM2 ZNF462 Zinc finger protein 462 1 S(0.947)LMPHY(0.053)QR 71.296 0.020287 1726100.0 4914.3 8033.4 4889.6 4765.8 12211.0 9769.6 4342.4 9837.3 10433.0 12846.0 True False 5746.193928150685 8830.902861108974 5006.186607911262 4498.787676932069 9818.342207396954 9257.264977602123 3931.0564357465105 9579.081298480918 10585.56288770315 15174.878111119953 0.37866491487269005 0.5819422598615671 0.3298996256347386 0.2964628541981775 0.6470129206640679 0.610038835884851 0.259050280797042 0.6312460125436851 0.697571526452406 1.0 13.889397307945464 -8.49160115360584 1.4345818196341649 0.9945697572732047 0.4531028880871361 0.621125640064945 0.13361113923051274 0.28415081884783217 1.2863334828120756 0.1292766171633376 0.03866891202148757 3.2240283079990495e-09 8.49160115360584 -0.5414668691860687 S(ph)LNLEDYKK ddPTM_PC-9_AZD4547_30min_R2 1 SLNLEDYKK 9 1 Q92541 Q92541 RTF1 RNA polymerase-associated protein RTF1 homolog 1 S(1)LNLEDYKK 82.48899999999999 0.023063999999999998 5822100.0 8243.2 11096.0 13395.0 19204.0 18448.0 13056.0 10118.0 15064.0 14419.0 11308.0 True False 10864.366130788578 14682.565005893597 13217.373547862473 14776.814498842348 15886.81363565934 12239.606256068642 11018.482398836779 12736.204936282977 15181.158903028087 10912.110361887324 0.9956246565040707 1.3455293723178718 1.211257319576489 1.3541665185547662 1.4558882845564995 1.1216534520048347 1.0097480719514147 1.167162401579685 1.3912211661688512 1.0 13.41364252009294 S(ph)LNLEDYKK ddPTM_PC-9_Lapatinib_30min_R1 1 SLNLEDYKK 9 1 Q92541 Q92541 RTF1 RNA polymerase-associated protein RTF1 homolog 1 S(1)LNLEDYKK 68.355 0.03954 0.0 13539.0 9458.6 12159.0 9673.3 13696.0 11927.0 10739.0 13613.0 12467.0 7670.5 True False 13345.931377251478 9436.69919283465 11159.333955097309 10384.706751182834 12890.428207372017 11416.91001319496 11295.012873669442 14245.509676699776 11062.835176669954 8996.335704701205 1.4834852561446 1.0489492058309169 1.2404310289650249 1.154326282617056 1.4328531782818954 1.2690622480026883 1.2555126047338385 1.5834791124185723 1.2297045752626663 1.0 13.13512178197959 -6.244024560193079 24.849195484954294 1.320994467596551 1.2193539768630413 0.016143735479568155 0.17413863968327845 2193.123507463267 3129366.0015231674 0.04881480869785968 0.06286103305243566 5.701320292998973e-07 6.244024560193079 -0.10164049073350978 S(ph)LNLVDSPQPLLEK ddPTM_PC-9_AZD4547_30min_R2 2 SLNLVDSPQPLLEK 14 0 P46019 P46019 PHKA2 Phosphorylase b kinase regulatory subunit alpha, liver isoform 1 S(1)LNLVDSPQPLLEK;S(0.994)LNLVDS(0.006)PQPLLEK 149.09 0.00022068 2965600.0 38966.0 26969.0 33007.0 43603.0 40344.0 31268.0 32867.0 40752.0 37753.0 40391.0 True False 51356.37745685024 35686.20184246076 32569.305613609336 33551.00200963458 34742.931988131 29312.807017061445 35792.09932818431 34454.71478779896 39748.54650572292 38976.92338406358 1.3176098316125235 0.9155725681789371 0.8356048344987097 0.8607914400794527 0.8913718418918687 0.7520554336273375 0.9182894959538689 0.8839772818468888 1.0197969222469425 1.0 15.250332596524698 -4.762669977641586 4.947243414109619 0.8847781316264138 1.3457196051288502 0.7481662650466747 0.07300228169472388 0.08226595252108156 5.203574270340882 0.017879280674170377 0.13239949745878798 1.7271498625021018e-05 4.762669977641586 0.4609414735024364 S(ph)LNLVDSPQPLLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLNLVDSPQPLLEK 14 0 P46019 P46019 PHKA2 Phosphorylase b kinase regulatory subunit alpha, liver isoform 1 S(0.807)LNLVDS(0.193)PQPLLEK 114.58 0.0020352 0.0 10279.0 9602.9 8289.0 10411.0 11971.0 9230.3 6609.7 8522.4 6995.9 8393.8 True False 12019.031680495873 10556.21244864483 8486.641196207558 9827.705422917412 9625.36848454253 8746.246818985515 5983.581365916022 8298.696030229206 7098.201802557504 9915.529494715756 1.2121421944134327 1.0646140939090052 0.8558938986294489 0.9911427753963973 0.9707367104976229 0.8820756192240281 0.6034555561661965 0.836939271337128 0.7158671462114374 1.0 13.275474099880094 -6.861254418218154 2.9504767390571236 0.7724747998978608 1.0144230002802699 0.4235212459828651 0.12571752198834069 0.24936079084311746 4.370446105636105 0.04778733988785721 0.04196999196190832 1.3764029088709726e-07 6.861254418218154 0.24194820038240905 S(ph)LNQNMESLRARAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLNQNMESLRARAAR 15 2 P02549-2;P02549 P02549-2 SPTA1 Spectrin alpha chain, erythrocytic 1 1 S(1)LNQNMESLRARAAR 68.277 0.025355000000000003 1758700.0 3376.4 3273.6 5535.6 3930.3 6454.4 4071.2 4093.1 5057.7 4161.2 2539.1 True False 3947.9578330602462 3598.5813735312977 5667.589697879905 3710.0980332045247 5189.70665329808 3857.699105062006 3705.3719365222128 4924.940734076115 4222.049677783028 2999.4187304954603 1.3162409745998023 1.1997595857304206 1.8895626810144315 1.2369390093765502 1.7302374625235524 1.2861489013988954 1.2353633385193068 1.6419650527629355 1.4076226286303168 1.0 11.550467226755345 S(ph)LNSTPPPPPAPAPAPPPALARPR ddPTM_PC-9_AZD4547_30min_R2 1 SLNSTPPPPPAPAPAPPPALARPR 24 1 B4DKV7;Q8TE68-2;Q8TE68;K7ELW3;Q8TE68-4 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 S(0.333)LNS(0.333)T(0.333)PPPPPAPAPAPPPALARPR 66.308 0.00064893 22425000.0 52616.0 117210.0 122860.0 144240.0 111500.0 139430.0 156190.0 192840.0 53415.0 67143.0 True False 69346.79351921254 155095.84033352465 121230.79612470207 110987.69648578527 96020.14963009622 130711.42005849018 170090.60741987714 163041.00902235846 56238.40785111623 64792.34400673859 1.0702930196814655 2.393737141496135 1.8710666820773412 1.7129754786189282 1.481967524127694 2.0173898947828746 2.6251652109111414 2.516362257327837 0.8679792144156303 1.0 15.983535730991898 -8.278848664494726 24.837571548037033 0.9339892132199814 1.9723057830951214 0.45238262561012477 0.4518998826695038 806.3615759209304 1150412.0955965756 0.44563985473114115 0.11618573033152248 5.262005958213809e-09 8.278848664494726 1.03831656987514 S(ph)LPAGDALYLSFNPPQPSR ddPTM_PC-9_AZD4547_30min_R2 4 SLPAGDALYLSFNPPQPSR 19 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF0 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 S(1)LPAGDALYLSFNPPQPSR;S(0.998)LPAGDALYLS(0.002)FNPPQPSR;S(1)LPAGDALYLSFNPPQPSR;S(1)LPAGDALYLSFNPPQPSR 141.6 3.282e-05 120685700.0 29262.8 31351.600000000002 32839.3 46605.399999999994 44416.7 44194.4 35515.700000000004 44165.0 31958.800000000003 38981.600000000006 True False 38567.76169594818 41485.39158604667 32403.829425182543 35861.245076252206 38250.207893050225 41430.91718161766 38676.52849697247 37340.31406073668 33648.07692281669 37616.866049075616 1.0252784388160356 1.1028401869502928 0.8614175721844544 0.9533288878841476 1.0168366456458213 1.1013920491825706 1.02816987588797 0.9926481916920421 0.894494423828897 1.0 15.199092039048692 -8.018512125361747 21.128945579583053 0.9460217739945906 1.0115866075875868 0.12144512129087814 0.06956700714689779 227.56803572422245 259726.3962670192 0.047629035622585796 0.01888011022893643 9.582699613448849e-09 8.018512125361747 0.06556483359299614 S(ph)LPAGDALYLSFNPPQPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SLPAGDALYLSFNPPQPSR 19 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF0 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 S(1)LPAGDALYLSFNPPQPSR;S(1)LPAGDALYLSFNPPQPSR;S(1)LPAGDALYLSFNPPQPSR;S(1)LPAGDALYLSFNPPQPSR;S(0.999)LPAGDALYLSFNPPQPSR;S(1)LPAGDALYLSFNPPQPSR 213.64 1.2574000000000001e-27 100916400.0 92480.1 93759.2 93587.4 116416.5 127961.09999999999 90650.09999999999 94335.2 93153.7 83589.4 73084.40000000001 True False 108135.1543647659 103066.993743034 95818.8785481911 109894.06093238543 102888.04103144215 85896.24917561922 85399.08692829662 90708.51407950376 84811.73683939187 86334.02318420804 1.2525207372074103 1.193816643099365 1.1098623116838369 1.2728940095599173 1.191743848330957 0.9949292991054667 0.9891707090503986 1.0506693738337898 0.9823674805288743 1.0 16.397641599509257 -6.749257648924762 8.36067705095571 1.0055618368128356 1.20248976762907 0.8398590914281797 0.0438225484706504 0.059893159528155604 27.388160146791375 0.014899613661074925 0.014361053556916581 1.781321669560482e-07 6.749257648924762 0.1969279308162344 S(ph)LPAGDALYLSFNPPQPSR ddPTM_PC-9_Lapatinib_30min_R1 4 SLPAGDALYLSFNPPQPSR 19 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF0 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 S(0.994)LPAGDALY(0.002)LS(0.003)FNPPQPSR;S(0.995)LPAGDALY(0.001)LS(0.004)FNPPQPSR;S(0.999)LPAGDALY(0.001)LSFNPPQPSR;S(1)LPAGDALYLSFNPPQPSR 130.95 3.9374e-05 108050000.0 131846.8 114072.6 117499.4 117382.3 115069.4 96219.1 98363.09999999999 113206.6 112000.5 96885.2 True False 129966.64045425788 113808.4719032996 107839.05289280055 126014.98591787397 108301.24412714469 92104.03339067717 103455.86002365545 118466.59191701154 99385.82427244911 113631.67772858578 1.143753599807695 1.0015558528946136 0.949022799349833 1.1089776058650322 0.9530902499374069 0.8105489176237605 0.9104491114772086 1.0425489994081947 0.8746313198845527 1.0 16.794005553391585 -1.5228787453876975 0.5658529416137464 0.9389697419767372 10.371248977899777 0.3483294554032359 0.07850042106368643 178.16631620310397 1.5503966642667133 0.03965587631970821 2054.620860073366 0.029999999992583837 1.5228787453876975 9.432279235923039 S(ph)LPAPQDNDFLSR ddPTM_PC-9_AZD4547_30min_R2 1 SLPAPQDNDFLSR 13 0 O43353-2;O43353 O43353-2 RIPK2 Receptor-interacting serine/threonine-protein kinase 2 1 S(1)LPAPQDNDFLSR 116.58 0.00027192 7444800.0 3498.7 5210.8 5669.4 8317.7 10081.0 4304.1 6461.8 10286.0 7996.2 7079.8 True False 4611.213822519168 6895.089197252193 5594.220051679849 6400.182772183973 8681.427160726465 4034.9639465950545 7036.887681834705 8696.535048765712 8418.86280743416 6831.938356923405 0.6749495650595587 1.009243473378941 0.8188335080644767 0.9368033547460368 1.2707121620804454 0.5906030961924693 1.029998708156318 1.2729235239590162 1.232280264780578 1.0 12.73807924255929 -7.526645061938594 16.49675186118803 1.1818639587600779 0.8983182947402554 0.31922660070871745 0.18635205972694757 1.9671501927792725 8588.883277459336 0.08433196780948751 0.049551290100026506 2.974095693074582e-08 7.526645061938594 -0.2835456640198225 S(ph)LPAPQDNDFLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLPAPQDNDFLSR 13 0 O43353-2;O43353 O43353-2 RIPK2 Receptor-interacting serine/threonine-protein kinase 2 1 S(1)LPAPQDNDFLSR;S(1)LPAPQDNDFLSR 85.163 0.0082281 9392500.0 6830.599999999999 7749.0 12041.9 11707.099999999999 18618.6 10341.8 15144.6 14303.9 10617.599999999999 10355.9 True False 7986.885669500445 8518.269508643092 12329.024565160058 11051.1891419303 14970.418984738411 9799.457802301593 13709.993850591065 13928.437781234818 10772.862313474254 12233.342692740709 0.6528784380609136 0.6963157758752112 1.0078214004808455 0.9033662686886142 1.2237390352533726 0.8010449840595582 1.1207070867659583 1.138563525200678 0.880614774232303 1.0 13.578531045665073 -5.239443517506409 3.6143676469569774 1.0172491768464569 0.657876513008225 0.5497110792036998 0.12129335154592752 0.1587684458371322 4.492496186219707 0.030723700890948877 0.08690418278800822 5.761777489151654e-06 5.239443517506409 -0.35937266383823185 S(ph)LPAPQDNDFLSR ddPTM_PC-9_Lapatinib_30min_R1 2 SLPAPQDNDFLSR 13 0 O43353-2;O43353 O43353-2 RIPK2 Receptor-interacting serine/threonine-protein kinase 2 1 S(1)LPAPQDNDFLSR;S(1)LPAPQDNDFLSR 104.94 0.001284 13965300.0 6552.7 11003.7 14901.2 14280.5 11301.0 13950.5 12476.2 10836.9 13977.1 13702.4 True False 6459.25729638199 10978.221608715308 13676.080856295417 15330.735608351493 10636.297398620847 13353.869635203846 13122.156589484566 11340.421936048471 12402.851812611976 16070.841582699664 0.40192402265575256 0.6831142944333055 0.850987223408249 0.9539472795783825 0.6618382331682536 0.8309377929267469 0.8165195656965861 0.7056520268519408 0.7717611892810706 1.0 13.97215786023614 -4.8236641528201645 2.6950619892116108 0.8114185171692524 0.34293431263810414 0.6367500311650656 0.09680651500053329 0.26261521281690176 2.753565717894439 0.024635041117451306 0.2685596482630255 1.500845015380547e-05 4.8236641528201645 -0.46848420453114825 S(ph)LPATPQGK ddPTM_PC-9_AZD4547_30min_R2 1 SLPATPQGK 9 0 Q13111;Q13111-3;Q13111-2;K7EPA1 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 S(0.87)LPAT(0.13)PQGK 94.363 0.005771500000000001 28026000.0 152480.0 143760.0 214950.0 280020.0 273960.0 228940.0 250060.0 243370.0 207670.0 223530.0 True False 200965.4682189736 190227.60861997702 212099.6225541649 215465.71526587344 235925.38289382283 214624.345608483 272314.8555695913 205762.75858624472 218647.01223329225 215704.28273723694 0.9316712012796815 0.8818907358075284 0.983288879862144 0.9988940067933 1.093744546468827 0.9949934367781216 1.2624452890502655 0.9539113270036339 1.0136424249843943 1.0 17.718695295452726 -5.678031201032329 1.6953566621075502 1.05788432919654 0.9059630654751089 0.31854248964615006 0.08154939607890702 0.43146238219021243 2.490943886713541 0.025353004282185364 0.05983848272150734 2.098789094835078e-06 5.678031201032329 -0.15192126372143122 S(ph)LPATPQGK ddPTM_PC-9_Lapatinib_30min_R1 1 SLPATPQGK 9 0 Q13111;Q13111-3;Q13111-2;K7EPA1 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 S(0.503)LPAT(0.497)PQGK 80.916 0.017991 25057000.0 142520.0 115790.0 137260.0 141890.0 144150.0 152060.0 142420.0 136250.0 168050.0 136460.0 True False 140487.6386650332 115521.89536911612 125975.012638922 152325.06393116422 135671.3804098041 145556.748269173 149793.81073358812 142580.67240507915 149122.43935504806 160046.92917847965 0.8777902793021759 0.7218001367604465 0.7871129629637463 0.9517524935532863 0.8476974916432626 0.9094629245079259 0.9359367999278665 0.8908679044136946 0.9317419591896767 1.0 17.288135470586283 -5.380127534947941 0.20612897782685907 1.0065866939181272 0.6494641236649745 0.501178173515091 0.055048965439764924 8.860051876594223 0.44599264636999153 0.1282368157923979 0.8264143518612531 4.167469835508835e-06 5.380127534947941 -0.35712257025315264 S(ph)LPEEDVAEIQHAEEFLIKPESK ddPTM_PC-9_AZD4547_30min_R2 4 SLPEEDVAEIQHAEEFLIKPESK 23 1 O60832;H7C2Q9;H7C0M1;C9IYT0;O60832-2 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 S(1)LPEEDVAEIQHAEEFLIKPESK;S(1)LPEEDVAEIQHAEEFLIKPESK;S(1)LPEEDVAEIQHAEEFLIKPESK;S(1)LPEEDVAEIQHAEEFLIKPESK 143.47 8.239200000000001e-09 64350100.0 133336.6 113873.2 147465.2 177337.5 179185.3 165902.0 118622.8 152154.8 144611.5 156081.3 True False 175734.86522642933 150680.4849882051 145509.71509594994 136455.07921206288 154308.51405841895 155528.12171371808 129179.99939718677 128642.77182947072 152255.36865977163 150616.94119445057 1.1667669243100007 1.0004218900825539 0.9660912905414334 0.9059743089317931 1.0245096788893253 1.0326070924048778 0.8576724395857427 0.8541055926994918 1.0108781087461192 1.0 17.200524526004585 -4.662595755492862 1.969898644362587 0.9507643433443189 1.2824301181996787 0.5066000205593921 0.06197735670002413 0.9723652662229214 3.1321930869398553 0.017595338960339935 0.6544391568697933 2.1747244866558335e-05 4.662595755492862 0.33166577485535975 S(ph)LPEEDVAEIQHAEEFLIKPESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLPEEDVAEIQHAEEFLIKPESK 23 1 O60832;H7C2Q9;H7C0M1;C9IYT0;O60832-2 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 S(1)LPEEDVAEIQHAEEFLIKPESK;S(1)LPEEDVAEIQHAEEFLIKPESK;S(1)LPEEDVAEIQHAEEFLIKPESK 137.86 6.3866e-08 45779000.0 225677.0 199661.5 224738.0 237875.0 276036.0 242095.0 250801.0 258330.0 220320.0 182350.0 True False 263879.65877607366 219482.57420311603 230096.6062436108 224547.63495115534 221948.72734100546 229399.1120161099 227043.31363800212 251549.1112232605 223541.76319550967 215408.61151819443 1.2250190784679242 1.0189127196735934 1.068186664506566 1.0424264534669683 1.0303614408760935 1.0649486591984916 1.0540122423045513 1.1677764851198322 1.037756854844349 1.0 17.716716400949636 -4.75294126428005 24.996334187736753 1.0587767649294264 1.2250193899686879 0.5845438996767995 0.04311697711916169 238.826046647035 702428.8499022848 0.010715182196183304 0.12149358228043802 1.766276682845118e-05 4.75294126428005 0.16624262503926146 S(ph)LPEEDVAEIQHAEEFLIKPESK ddPTM_PC-9_Lapatinib_30min_R1 3 SLPEEDVAEIQHAEEFLIKPESK 23 1 O60832;H7C2Q9;H7C0M1;C9IYT0;O60832-2 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 S(1)LPEEDVAEIQHAEEFLIKPESK;S(1)LPEEDVAEIQHAEEFLIKPESK;S(1)LPEEDVAEIQHAEEFLIKPESK 133.53 9.7604e-09 24803200.0 75815.0 61332.0 69189.0 57819.0 64797.0 60265.0 57891.0 52623.0 60125.0 51246.0 True False 74733.86419723176 61189.98952222687 63500.54749726347 62071.202138529785 60985.7678558035 57687.60643457649 60888.31271716152 55068.05668970638 53353.089355681455 60103.80281899724 1.2434132399624194 1.018071846576841 1.0565146383248916 1.0327333584109042 1.014674030517874 0.9597996088251333 1.013052583386892 0.9162158483639377 0.8876824236289079 1.0 15.875168653922572 -1.5228787452803376 0.4637466675700721 0.9535979036080287 7.175220926837736 0.7284385079003963 0.047606667863909234 50.83999892856991 0.5932128423750579 0.029253699473464234 302.06461505841986 0.029999999999999995 1.5228787452803376 6.221623023229707 S(ph)LPELDRDKSDSDTEGLLFSR ddPTM_PC-9_AZD4547_30min_R2 1 SLPELDRDKSDSDTEGLLFSR 21 2 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 S(0.739)LPELDRDKS(0.234)DS(0.025)DT(0.002)EGLLFSR 46.295 0.021828999999999998 3271200.0 6264.5 7290.1 6232.0 12880.0 10135.0 7404.3 7644.6 6254.0 8942.9 9290.1 True False 8256.480690305352 9646.482259324528 6149.359608083536 9910.714994016324 8727.93019283432 6941.307950506209 8324.954590447493 5287.588002623058 9415.603436707797 8964.856426686363 0.920983036128461 1.0760331008323925 0.6859406682496637 1.10550738598717 0.9735716644444223 0.7742798791337577 0.9286210725769097 0.5898129039616403 1.0502793339422214 1.0 13.13006476299654 -6.7428553447823525 24.919552756637884 0.846713333300194 0.9529771713022491 0.056323344160474464 0.15939063111410057 577.3672577134085 774196.8081009233 0.050090284105571196 0.05000428914270168 1.8077761615393367e-07 6.7428553447823525 0.10626383800205508 S(ph)LPGPAPCLK ddPTM_PC-9_AZD4547_30min_R2 1 SLPGPAPCLK 10 0 E9PJF6;A0A5F9UK94;H0Y360;Q01433-2;Q01433 E9PJF6 AMPD2 AMP deaminase 2 1 S(1)LPGPAPCLK 117.25 0.00097252 10259000.0 31372.0 34976.0 48669.0 77730.0 58374.0 47251.0 46070.0 72009.0 61517.0 53416.0 True False 41347.64342186279 46281.3080070417 48023.61726024032 59810.54941652857 50269.77770858512 44296.387500421246 50170.14075058418 60881.66365220391 64768.663030555406 51545.92209856504 0.8021515910181738 0.8978655560481301 0.9316666635318028 1.1603352308289312 0.9752425732623484 0.8593577473639644 0.9733095986652422 1.181115036331822 1.2565235113401623 1.0 15.653570677154745 -7.722273829817369 5.715631237403128 1.164708917216726 0.945731716358498 0.4301574978830197 0.10662882320794916 0.17007117961875035 13.897307413866633 0.055221047841510065 0.030311902820862914 1.8955103938560373e-08 7.722273829817369 -0.21897720085822803 S(ph)LPGPAPCLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLPGPAPCLK 10 0 E9PJF6;A0A5F9UK94;H0Y360;Q01433-2;Q01433 E9PJF6 AMPD2 AMP deaminase 2 1 S(1)LPGPAPCLK 71.03 0.034231 6097100.0 34554.0 26965.0 19848.0 21088.0 33488.0 33599.0 32537.0 35360.0 31737.0 28260.0 True False 40403.30972739122 29641.906994523295 20321.25159395918 19906.507728218443 26926.26679561943 31837.009292340917 29454.8598125194 34431.837467016885 32201.093584494847 33383.31429396309 1.210284556278991 0.887925828259767 0.6087248082984378 0.5963011207613457 0.8065785966760248 0.9536803030398392 0.8823228141205232 1.031408600231266 0.9645864787702629 1.0 15.0268395720601 -6.768121592986806 5.7400704868621935 0.9641411303047209 0.8006079805163396 0.15791399809371032 0.1632594259172878 0.31621273119294313 35.02836372152391 0.06179942759331918 0.05741797882404027 1.7056047899905662e-07 6.768121592986806 -0.1635331497883813 S(ph)LPGPAPCLK ddPTM_PC-9_Lapatinib_30min_R1 1 SLPGPAPCLK 10 0 E9PJF6;A0A5F9UK94;H0Y360;Q01433-2;Q01433 E9PJF6 AMPD2 AMP deaminase 2 1 S(1)LPGPAPCLK 69.65 0.037828 7820400.0 35508.0 43790.0 40202.0 37816.0 52817.0 45607.0 43608.0 49357.0 58901.0 52126.0 True False 35001.6494086303 43688.606945449574 36896.74674420774 40597.114790477935 49710.40790221727 43656.494925109626 45865.808864417275 51650.306406587144 52266.949124972896 61135.909646470944 0.5725219369603468 0.7146144908628425 0.6035200417818204 0.6640469574303847 0.8131130818151945 0.7140892345850568 0.7502269800129631 0.8448439993003137 0.8549304234976733 1.0 15.899732410181958 -7.590715850572794 0.19148791476230967 1.0914846983471367 0.4922376043689534 0.8393296464795774 0.04897300034800781 1.3118435329697946 0.22698044158854985 0.2457725501491433 0.32040740686301794 2.5661624716294085e-08 7.590715850572794 -0.5992470939781833 S(ph)LPGSPEFLHQEACPFVGR ddPTM_PC-9_AZD4547_30min_R2 2 SLPGSPEFLHQEACPFVGR 19 0 Q96S53-3;Q96S53-2;Q96S53 Q96S53-3 TESK2 Dual specificity testis-specific protein kinase 2 1 S(0.733)LPGS(0.267)PEFLHQEACPFVGR;S(0.558)LPGS(0.442)PEFLHQEACPFVGR 94.564 0.00042874 5787100.0 7435.200000000001 3748.59 7587.5 6051.2 8184.8 6883.7 9720.9 9462.5 9247.7 5904.299999999999 True False 9799.43893823264 4960.248409827203 7486.884792415571 4656.189330108044 7048.481799931949 6453.261150804212 10586.041268121413 8000.288051618268 9736.51454244627 5697.592254129048 1.719926330483018 0.8705867651783099 1.314043627286565 0.8172205244651722 1.2370983190002602 1.1326295148845602 1.857985056836895 1.404152437517875 1.7088822976741118 1.0 12.476136664134573 -7.219439257982358 24.586937260911323 1.5264345008562399 1.15970281880393 0.18622068603243802 0.31314149431283 550.0333397043387 321990.5442242611 0.11139848631248105 0.08628811873964964 6.033380871013839e-08 7.219439257982358 -0.3667316820523099 S(ph)LPGSPEFLHQEACPFVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLPGSPEFLHQEACPFVGR 19 0 Q96S53-3;Q96S53-2;Q96S53 Q96S53-3 TESK2 Dual specificity testis-specific protein kinase 2 1 S(0.951)LPGS(0.049)PEFLHQEACPFVGR;S(0.996)LPGS(0.004)PEFLHQEACPFVGR 122.5 1.8169000000000002e-05 4569900.0 7787.5 11492.0 8920.1 11404.4 12439.8 10199.5 9264.4 6506.0 8587.07 9011.8 True False 9105.76993986395 12632.849812017872 9132.78901366763 10765.448441563662 10002.310489851496 9664.620264806428 8386.808963552407 6335.224393676806 8712.639653609605 10645.568002630447 0.8553578294379386 1.186676916524922 0.857895887886018 1.0112610655348397 0.9395750877153753 0.9078538845854318 0.7878216513651581 0.5951044032701135 0.8184288195291008 1.0 13.37796530751875 -7.090393666995909 2.3921982536446844 0.7654526074762339 0.9784036005504108 0.26814455250518177 0.12746309085618707 0.32527588991329937 3.659475849466028 0.05327236389739697 0.03974641100545493 8.120940583472471e-08 7.090393666995909 0.21295099307417686 S(ph)LPGSPEFLHQEACPFVGR ddPTM_PC-9_Lapatinib_30min_R1 2 SLPGSPEFLHQEACPFVGR 19 0 Q96S53-3;Q96S53-2;Q96S53 Q96S53-3 TESK2 Dual specificity testis-specific protein kinase 2 1 S(0.521)LPGS(0.479)PEFLHQEACPFVGR;S(0.874)LPGS(0.126)PEFLHQEACPFVGR 108.28 0.00010573 5664100.0 2646.5 4451.36 7376.3 3998.35 4653.1 4461.799999999999 4732.4 3491.5 2531.94 4574.27 True False 2608.7604246913406 4441.053149410742 6769.849087341416 4292.4019971045955 4379.413806346577 4270.9792149638015 4977.420516188963 3653.727836347411 2246.7662546897973 5364.926474668355 0.4862621020081374 0.8277938514870841 1.261871736603792 0.8000858944427454 0.8163045340928555 0.796092776877771 0.9277704996873519 0.6810396849983438 0.41878789304911884 1.0 12.389342683908897 -7.8309798173084 7.3428512361754095 0.6594182540387186 0.8555982464723173 0.07339145154971372 0.22131219944878475 0.4966607807951814 43.84746184755343 0.12169704185212646 0.05825611124844569 1.4757751144418213e-08 7.8309798173084 0.19617999243359874 S(ph)LPITIEMLK ddPTM_PC-9_AZD4547_30min_R2 1 SLPITIEMLK 10 0 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 S(1)LPITIEMLK 75.819 0.02112 10069000.0 27309.0 41430.0 40104.0 35067.0 36980.0 38918.0 47501.0 54701.0 50518.0 43498.0 True False 35992.69393751278 54821.437292192844 39572.19475651189 26982.84492974925 31845.965321264222 36484.45130772669 51728.49697836983 46248.2173539309 53188.27834545897 41975.148259760754 0.8574762789347186 1.306045113954895 0.9427529478066802 0.6428290559634833 0.7586861903187888 0.8691917198706433 1.232360077878726 1.1017999762079815 1.2671373550917895 1.0 15.35724780044121 -7.255505332180903 24.810377346794606 1.1588076868615986 0.899148047506185 0.33936020979336345 0.17353516483798873 560.918676698577 2345217.6782080196 0.07407394072970837 0.05581562049758604 5.552577997333546e-08 7.255505332180903 -0.2596596393554136 S(ph)LPITIEMLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLPITIEMLK 10 0 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 S(0.987)LPIT(0.013)IEMLK;S(0.932)LPIT(0.068)IEMLK 70.41199999999999 0.031564 34024000.0 74263.0 99368.0 73252.0 68482.0 80816.0 46682.0 66736.0 58099.0 46858.0 42542.0 True False 86834.25913889142 109232.59833976605 74998.60548975697 64645.17556163958 64980.68494251015 44233.91374103567 60414.28295320086 56573.96281097893 47543.20960337336 50254.52783771329 1.727889264412251 2.1735871978045513 1.4923750897023569 1.2863552468425918 1.293031448874656 0.8801975790893914 1.202165964991183 1.1257485692368447 0.9460482796078479 1.0 15.616965965785944 -5.658164220542913 1.4977819904435485 1.0741823244367787 1.972784192407449 0.8136914988242497 0.16226907665356552 0.16312879874783545 0.7221284272825174 0.05005114905616318 0.13162435738809722 2.197028949241158e-06 5.658164220542913 0.8986018679706702 S(ph)LPITIEMLK ddPTM_PC-9_Lapatinib_30min_R1 1 SLPITIEMLK 10 0 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 S(0.997)LPIT(0.003)IEMLK 67.385 0.038512 9188600.0 21603.0 45413.0 35310.0 18386.0 25542.0 31483.0 28365.0 32423.0 34615.0 28695.0 True False 21294.937258495 45307.848988666425 32406.94810054164 19738.167773898 24039.66977750411 30136.54548045752 29833.60090898907 33929.490945980826 30716.294187890457 33654.89251631592 0.632744176739569 1.3462485125067964 0.9629193759816859 0.5864873216971029 0.7142994073105317 0.8954580813427735 0.8864565796644786 1.0081592425092958 0.9126843644798203 1.0 15.038528628692625 -9.507501293698112 12.350250739203055 0.9999972003192751 0.8893047503389924 0.0279184197174267 0.20422641362687233 0.0 0.0 0.2041113669122814 0.049504277951090477 3.108126644082667e-10 9.507501293698112 -0.11069244998028271 S(ph)LPLGVEELGQLPPVEGPGGRPLRK ddPTM_PC-9_AZD4547_30min_R2 1 SLPLGVEELGQLPPVEGPGGRPLRK 25 2 H0Y8W3;O43566-4;O43566-5;O43566 H0Y8W3 RGS14 Regulator of G-protein signaling 14 1 S(1)LPLGVEELGQLPPVEGPGGRPLRK 65.881 0.00026219 2331900.0 7599.6 4783.5 9512.1 13828.0 9571.5 9727.5 9995.3 9874.0 7200.7 7990.9 True False 10016.114718500212 6329.672828559124 9385.96333890427 10640.168240470324 8242.662441116296 9119.237887247831 10884.862336538186 8348.20018194756 7581.3143014796 7711.141023240662 1.2989147375612211 0.8208477590387828 1.2171951350151486 1.3798435547219077 1.0689290231204016 1.1826055132130635 1.4115760953835785 1.0826154205696488 0.9831637469254191 1.0 12.912728637250376 -7.99437713467851 24.995630885431513 1.0053510504599965 1.1894052866038514 0.21723938237590845 0.15789475166919517 233.06350128620193 1036050.3698556203 0.08873535362750101 0.0424255549416806 1.0130313027940986e-08 7.99437713467851 0.18405423614385485 S(ph)LPLPTPEEK ddPTM_PC-9_Lapatinib_30min_R1 1 SLPLPTPEEK 10 0 Q5SYE7-2;Q5SYE7;E9PAK2 Q5SYE7-2 NHSL1 NHS-like protein 1 1 S(1)LPLPTPEEK 83.045 0.035809 0.0 39375.0 52923.0 49480.0 41599.0 40727.0 51192.0 46561.0 44185.0 41972.0 35975.0 True False 38813.50527950936 52800.46004507946 45411.945398323434 44658.329230196 38331.51793236275 49002.63749438053 48971.700755277285 46237.996405272876 37244.67137524593 42193.23081632569 0.9198988683391217 1.251396468664105 1.0762850940713538 1.0584240259913091 0.9084755348370067 1.1613862353346995 1.1606530196386105 1.095862902903898 0.8827167451902018 1.0 15.364723941253017 -8.249333028846209 24.35108787004052 0.9413583744736719 1.0837922341448718 0.22254484334400337 0.10263520881242141 678.169672269056 1364100.8830955701 0.06994410716106557 0.025962535173541457 5.6320560878239395e-09 8.249333028846209 0.14243385967119992 S(ph)LPLSPELESSP ddPTM_PC-9_AZD4547_30min_R2 2 SLPLSPELESSP 12 0 Q6DT37 Q6DT37 CDC42BPG Serine/threonine-protein kinase MRCK gamma 1 S(0.998)LPLS(0.002)PELESSP;S(0.998)LPLS(0.002)PELESSP 158.05 0.00045363 3326100.0 14395.6 17012.1 20076.0 28769.0 23462.3 20030.8 18513.6 26241.9 20403.3 20861.7 True False 18973.101352918773 22510.92863525255 19809.779122574637 22136.751526619217 20204.964633777658 18778.27090947149 20161.274534404503 22186.817333871757 21481.776783837497 20131.33823280728 0.9424659768519028 1.1182032895640956 0.9840269381740052 1.0996164919897768 1.0036573028637705 0.932788009039024 1.001487049755512 1.1021034507142073 1.0670814098602475 1.0 14.297155458299647 -7.741362864272995 24.991331795960058 1.063444347054371 1.0148087339119267 0.09781932958178385 0.06051937696889163 511.7575902623029 637038.8168184429 0.028432391485568073 0.01639105942387617 1.8139993860096002e-08 7.741362864272995 -0.048635613142444356 S(ph)LPLSPELESSP ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLPLSPELESSP 12 0 Q6DT37 Q6DT37 CDC42BPG Serine/threonine-protein kinase MRCK gamma 1 S(0.983)LPLS(0.017)PELES(0.001)SP 135.99 6.204399999999999e-05 1062700.0 8324.1 9169.4 10177.0 14266.0 12813.0 11415.0 11005.0 9720.4 11183.0 8877.9 True False 9733.205721530854 10079.67743354652 10419.658276487426 13466.722270996033 10302.38462889011 10816.377305040965 9962.5267306997 9465.249799615134 11346.530218842548 10487.392992582269 0.9280862964146713 0.9611232687356976 0.993541319931202 1.284086739242159 0.9823589748354986 1.0313695036212895 0.949952646739394 0.9025360074052631 1.081920952792362 1.0 13.356368469846634 -7.2058077769259405 8.692164103979767 0.9755247931579382 1.0347707580697794 0.04519144878753678 0.10065915343907945 1.2361358319194857 184.03644467924988 0.040491258356847276 0.03129108486545623 6.225757824533827e-08 7.2058077769259405 0.0592459649118412 S(ph)LPLSPELESSP ddPTM_PC-9_Lapatinib_30min_R1 2 SLPLSPELESSP 12 0 Q6DT37 Q6DT37 CDC42BPG Serine/threonine-protein kinase MRCK gamma 1 S(1)LPLSPELESSP;S(1)LPLSPELESSP 147.91 0.00012602 2111630.0 25453.0 24290.4 23916.0 17989.5 20531.4 20495.2 19289.5 20262.0 23178.3 14644.099999999999 True False 25090.035552491463 24234.15707119773 21949.718798429723 19312.507841212777 19323.783418285468 19618.668072644698 20288.215925751636 21203.446490067654 20567.71577568052 17175.313172963302 1.4608196834505005 1.4109877838702924 1.2779807027322274 1.1244341018255062 1.1250906008924602 1.1422597000168606 1.181242852543064 1.234530414469838 1.1975162006394973 1.0 14.06804878479148 -5.4055938042449405 2.2725451386432347 1.1540880820031283 1.4503645061987804 0.789539638250689 0.06024116650178593 0.1412854478947789 1.3925688167334547 0.0170847808538466 0.04813972427729926 3.930123481155439e-06 5.4055938042449405 0.29627642419565214 S(ph)LPNLSR ddPTM_PC-9_AZD4547_30min_R2 1 SLPNLSR 7 0 Q9P270;D6RIF6 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 S(0.919)LPNLS(0.081)R 76.22800000000001 0.031564 29692000.0 15816.0 12061.0 20853.0 24080.0 22308.0 15989.0 18568.0 25484.0 13639.0 18667.0 True False 20845.15900676341 15959.48238429007 20576.475594891835 18528.728032291394 19210.919264109318 14989.205302411277 20220.516029017726 21546.033364062347 14359.929695429633 18013.4740117926 1.1571981613939117 0.8859747083678653 1.1422824704119456 1.0286038118000713 1.066474975983689 0.832110746244646 1.122521730998711 1.1961065006093294 0.7971771400690861 1.0 14.136788820441726 S(ph)LPNLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLPNLSR 7 0 Q9P270;D6RIF6 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 S(0.993)LPNLS(0.007)R;S(1)LPNLSR 76.282 0.031484 25339000.0 22044.4 33242.0 36601.0 36124.0 33376.0 36492.0 31672.0 31492.0 27644.0 24455.0 True False 25776.081523253553 36542.046071275494 37473.706650065455 34100.089395588155 26836.212391620717 34578.29527950549 28671.7988745771 30665.368368532134 28048.241202690107 28888.497914326505 0.8922610514294192 1.264934098673002 1.2971843244048122 1.1804036851177746 0.9289583858325839 1.1969571897456557 0.9924987778737385 1.0615078866154697 0.9709137971060899 1.0 14.81820757106395 -6.228339651549231 23.998626558003465 1.035173595764442 1.1761763410231607 0.21630824088406853 0.1218537569454339 597.3354558855102 433091.24068696675 0.03562552213324644 0.0459883691323122 5.910991685327845e-07 6.228339651549231 0.1410027452587188 S(ph)LPNLSR ddPTM_PC-9_Lapatinib_30min_R1 1 SLPNLSR 7 0 Q9P270;D6RIF6 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 S(1)LPNLSR 94.40899999999999 0.013456999999999998 12622000.0 25099.0 18181.0 20997.0 21601.0 16710.0 17047.0 15865.0 21179.0 15640.0 14453.0 True False 24741.08365740712 18138.903011537303 19270.707710763898 23189.609598823612 15727.150653124003 16317.939548497907 16686.41207195882 22163.053657740726 13878.45850349868 16951.18179258804 1.45954919014704 1.0700671630734677 1.1368356464202443 1.3680231787121384 0.9277908080721989 0.9626431801724279 0.9843804565446292 1.3074636287265584 0.8187310285095923 1.0 14.049098237387282 -1.522878745280348 0.46891541604386244 1.0249277804245673 10.173153884725593 0.3495840425190174 0.16074803129459572 121.42517023110968 1.3991927107297275 0.09590657277973552 1075.9138046369171 0.029999999999999274 1.522878745280348 9.148226104301026 S(ph)LPS(ph)SPLLTHQSISVR ddPTM_PC-9_AZD4547_30min_R2 2 SLPSSPLLTHQSISVR 16 0 J3QQY7;J3KTM5 J3QQY7 TANC2 2 S(0.952)LPS(0.578)S(0.471)PLLTHQSISVR;S(0.976)LPS(0.812)S(0.212)PLLTHQSISVR 102.79 0.0022208 0.0 7896.400000000001 8497.599999999999 17833.1 26838.0 23108.0 12924.599999999999 9635.5 23682.0 16279.1 17805.9 True False 10407.290944676699 11244.283020375033 17596.621442059455 20650.913742966626 19899.853073114497 12116.422718840744 10493.040833563144 20022.491058221814 17139.57999155867 17182.520860694152 0.6056905752684916 0.6544024076290734 1.0241001064234165 1.2018558807751307 1.1581451426394815 0.7051597851720144 0.6106811054463192 1.1652825112538772 0.9975008981811445 1.0 14.068654090439557 -5.236751613283351 7.7214436137322995 0.9796646042578465 0.6279671212297505 0.37556851955410464 0.18194292443338217 0.2681781359745998 68.90463017308376 0.05169466873902729 0.1327988299878891 5.797601847652371e-06 5.236751613283351 -0.351697483028096 S(ph)LPSDLAFNGDLAK ddPTM_PC-9_AZD4547_30min_R2 1 SLPSDLAFNGDLAK 14 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 S(1)LPSDLAFNGDLAK 123.72 0.00093678 0.0 4237.2 5627.2 6635.6 7532.0 6734.5 5359.7 4570.6 8323.3 6689.5 5471.2 True False 5584.5414607649145 7446.082354106385 6547.607608375982 5795.613768239982 5799.530920931693 5024.557111722665 4977.37454557456 7037.125235406538 7043.0933131150805 5279.6549533036705 1.0577474304964694 1.4103350351422308 1.2401582425910063 1.0977258588865657 1.098467792351225 0.9516828573387391 0.942746181255659 1.332875973457916 1.3340063650765592 1.0 12.366227931400392 -5.735204607029924 6.673988645371388 1.1081497594050367 1.2547861635591901 0.12742152296862463 0.15113400078018274 0.3490780716647633 52.68118619064512 0.044206435322714566 0.0748385390221141 1.8399049718369116e-06 5.735204607029924 0.14663640415415347 S(ph)LPSRSPPITPNWR ddPTM_PC-9_AZD4547_30min_R2 1 SLPSRSPPITPNWR 14 1 J3KN34;P26045-2;P26045 J3KN34 PTPN3 Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 3 1 S(0.589)LPS(0.351)RS(0.06)PPITPNWR 53.21 0.040235 8769900.0 33592.0 33877.0 53091.0 72504.0 79049.0 63976.0 46657.0 49011.0 43715.0 46810.0 True False 44273.557242994226 44827.077749158045 52386.978650956815 55789.32297563353 68074.41083506258 59975.57060648347 50809.38261341447 41437.47611073852 46025.68565405873 45171.19614785513 0.9801280687382566 0.9923819064350053 1.159743002586933 1.235064105741698 1.5070313970044151 1.3277392613241943 1.1248181794235497 0.9173429008854374 1.0189166898172604 1.0 15.463115496861082 -7.585090496615128 5.208962163734725 0.9791674109929717 1.2063672165233292 0.3161773474608005 0.1453457187910208 0.27840628192441813 14.98916879156711 0.08141296490080119 0.046251338628265304 2.5996178083543707e-08 7.585090496615128 0.22719980553035757 S(ph)LPSSPER ddPTM_PC-9_AZD4547_30min_R2 1 SLPSSPER 8 0 O95685 O95685 PPP1R3D Protein phosphatase 1 regulatory subunit 3D 1 S(0.997)LPS(0.001)S(0.002)PER 79.48899999999999 0.020640000000000002 3111100.0 12260.0 11538.0 16721.0 18176.0 19059.0 14490.0 14862.0 17414.0 12945.0 16224.0 True False 16158.424976158281 15267.432862112504 16499.268614692675 13985.804016400667 16412.986832287057 13583.938009377654 16184.689208491041 14723.066433910762 13629.246272258717 15656.002698201277 1.032091351007159 0.9751807761164083 1.053862146854911 0.893318957974343 1.0483510477532525 0.8676504642489821 1.0337689332635658 0.9404103153100696 0.8705444509040986 1.0 13.934428289265107 -5.608540534406508 0.7032209540199343 0.9468273646467007 1.0309035651141691 0.13065285283902472 0.06534683922918107 2.6371401670400147 2.0031515157219233 0.03163941936372021 0.1504895633780803 2.4629719486798162e-06 5.608540534406508 0.08407620046746844 S(ph)LPTTVPES(ph)PNYR ddPTM_PC-9_AZD4547_30min_R2 5 SLPTTVPESPNYR 13 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YC33 Q6PKG0 LARP1 La-related protein 1 2 S(1)LPTTVPES(1)PNYR;S(1)LPTTVPES(1)PNYR;S(1)LPTTVPES(1)PNYR;S(1)LPTTVPES(1)PNYR;S(0.996)LPT(0.003)T(0.001)VPES(1)PNYR 220.27 8.7619e-14 460055200.0 241944.0 209298.0 320808.0 415052.0 381504.0 357132.0 302640.0 349787.0 295518.0 347744.0 True False 318877.1592521737 276949.4854545345 316553.8763077766 319368.1738894769 328538.7548383884 334800.47958350973 329574.37370863475 295735.4564556306 311138.4781680457 335569.58840503613 0.9502564304703485 0.8253116343792556 0.9433330291113646 0.9517196579327566 0.9790480609400115 0.9977080496919224 0.9821342132792883 0.8812939750031064 0.9271951002678412 1.0 18.356252449316784 -5.495342876799658 21.890119668759638 0.9574051843412685 0.8869184949141965 0.29663291321398555 0.04366184630416594 186.0284982620476 147884.13804782514 0.01167655401713017 0.024151054594041724 3.196370569078554e-06 5.495342876799658 -0.07048668942707204 S(ph)LPTTVPES(ph)PNYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SLPTTVPESPNYR 13 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YC33 Q6PKG0 LARP1 La-related protein 1 2 S(0.999)LPTT(0.001)VPES(1)PNYR;S(1)LPTTVPES(1)PNYR;S(1)LPTTVPES(1)PNYR;S(1)LPTTVPES(1)PNYR;S(1)LPTTVPES(1)PNYR 207.85 6.959e-09 274583000.0 168471.8 179325.5 181818.8 219511.3 287928.0 311270.0 315340.0 298764.0 302936.0 239687.7 True False 196990.74827027574 197127.75051905736 186154.0497436386 207212.79352623658 231510.57530844214 294946.4532404818 285468.7123361061 290921.76156662486 307365.8659013943 283141.18264321034 0.695733296129183 0.6962171616251969 0.6574601688310866 0.7318355867268802 0.8176506615788613 1.0416939368800597 1.008220385572906 1.027479502807682 1.0855569049759524 1.0 18.11116207770401 -6.570082999399042 2.097250994494685 1.0376230551987142 0.6888693006809972 0.9670028837822116 0.029511349345278427 0.05043466166993473 0.44963070702653063 0.010841929976362645 0.011339170928691513 2.6910204653042617e-07 6.570082999399042 -0.34875375451771706 S(ph)LPTTVPES(ph)PNYR ddPTM_PC-9_Lapatinib_30min_R1 6 SLPTTVPESPNYR 13 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YC33 Q6PKG0 LARP1 La-related protein 1 2 S(1)LPTTVPES(1)PNYR;S(1)LPTTVPES(1)PNYR;S(0.995)LPTT(0.005)VPES(1)PNYR;S(1)LPTTVPES(1)PNYR;S(1)LPTTVPES(1)PNYR;S(1)LPTTVPES(1)PNYR 244.57 6.5313e-33 389248500.0 247844.0 222112.0 269039.0 239524.0 341116.0 354223.0 324258.0 335486.0 418681.0 344881.0 True False 244309.69911097668 221597.7133105211 246919.65194057307 257139.39398864104 321052.22753985977 339073.70802414295 341046.4926334208 351073.9043118567 371524.73687361414 404493.2213249532 0.6039896003960677 0.5478403632690265 0.6104420022955291 0.6357075481916812 0.7937147289841469 0.8382679613603341 0.843145137306116 0.8679351984240508 0.918494346225759 1.0 18.625755999977557 -6.4743619881187096 0.5133297914562576 0.9624024267593423 0.5128354933909735 0.9453949545770192 0.03429238824974654 0.2509762478500871 0.13715619713053576 0.030860727713023235 0.0533396122887187 3.3545789069801257e-07 6.4743619881187096 -0.44956693336836884 S(ph)LPTTVPESPNYR ddPTM_PC-9_AZD4547_30min_R2 4 SLPTTVPESPNYR 13 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YC33 Q6PKG0 LARP1 La-related protein 1 1 S(1)LPTTVPESPNYR;S(0.987)LPT(0.005)T(0.004)VPES(0.004)PNYR;S(1)LPTTVPESPNYR;S(1)LPTTVPESPNYR 237.41 4.9138e-26 684532000.0 167986.0 128101.0 213957.0 310723.0 262202.0 212349.0 193052.0 247231.0 185064.0 220467.0 True False 221402.05367413806 169507.1430984117 211119.79038297967 239090.61297249474 225799.77823596896 199070.7834612377 210233.25400872086 209027.12975319792 194846.10522435585 212748.51743493218 1.040674954371198 0.796748880519247 0.9923443553375142 1.1238179981471275 1.0613459541734689 0.935709380546552 0.9881772928124841 0.9825080441142325 0.9158517651430794 1.0 17.69878955277943 -5.489292976538218 24.763434520089156 1.0040821068626 0.912670564067331 0.14753704001988532 0.07786737591476542 923.4003862875072 680839.2988667614 0.020563260478341217 0.0427614146133577 3.2412089052287654e-06 5.489292976538218 -0.09141154279526897 S(ph)LPTTVPESPNYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SLPTTVPESPNYR 13 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YC33 Q6PKG0 LARP1 La-related protein 1 1 S(1)LPTTVPESPNYR;S(0.8)LPT(0.034)T(0.164)VPES(0.001)PNYR;S(0.998)LPTTVPES(0.001)PNYR;S(0.999)LPT(0.001)TVPESPNYR;S(1)LPTTVPESPNYR 211.83 1.2324e-10 351206000.0 97272.0 117349.0 132742.0 143412.0 187261.0 161026.0 161628.0 179933.0 178488.0 119032.0 True False 113738.22839042672 128998.6331874771 135907.0727068382 135377.09058797747 150568.5513143362 152581.5130899278 146317.4257546145 175209.94940477246 181098.0493338793 140611.55934320617 0.8088824910391134 0.9174112981182143 0.9665426750237139 0.9627735530444381 1.070812044312992 1.0851278074337063 1.0405789284896656 1.2460565135837671 1.2879314487356852 1.0 17.101355674264248 -5.987711942675637 0.5885180453347003 1.1745498655271251 0.8105311280302084 0.63408798959804 0.08300664387344726 0.781506728430597 0.4976574297872092 0.05712312060738705 0.1641029954196914 1.0286983833602191e-06 5.987711942675637 -0.3640187374969167 S(ph)LPTTVPESPNYR ddPTM_PC-9_Lapatinib_30min_R1 3 SLPTTVPESPNYR 13 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YC33 Q6PKG0 LARP1 La-related protein 1 1 S(1)LPTTVPESPNYR;S(1)LPTTVPESPNYR;S(1)LPTTVPESPNYR 276.12 1.0555999999999998e-68 328668000.0 128019.0 108153.0 111574.0 128059.0 111893.0 134348.0 125342.0 118556.0 171406.0 131003.0 True False 126193.42558419037 107902.57837340061 102400.81640809485 137476.88605230115 105311.67373010196 128602.24922048429 131831.59545688392 124064.54456995676 152100.4512948014 153646.69399947498 0.8213221013699232 0.7022772541644751 0.6664693768708408 0.8947598055885987 0.6854145116227611 0.8369997809450018 0.8580177810876581 0.8074664110272408 0.9899363750405273 1.0 17.22925719937696 -7.99260977455793 0.6637238474158518 1.0103362860582754 0.7482957529525599 0.5776880920091638 0.07233898439945231 0.4906448123042692 0.45871174075830917 0.06754577988825249 0.03200481324322863 1.017162230408157e-08 7.99260977455793 -0.2620405331057155 S(ph)LPVSICR ddPTM_PC-9_AZD4547_30min_R2 2 SLPVSICR 8 0 O94885;A0A087WW74 O94885 SASH1 SAM and SH3 domain-containing protein 1 1 S(1)LPVSICR;S(1)LPVSICR 191.17 2.7806999999999997e-05 37383000.0 36070.0 29292.0 45587.0 58082.0 53124.0 49549.0 38930.0 48975.0 36958.0 42408.0 True False 47539.50969739227 38760.066163719806 44982.48659398333 44692.09225795463 45748.64958698866 46450.693197146546 42394.694582596974 41407.03908354078 38911.52442874763 40923.30882799057 1.161673165217676 0.9471391066308119 1.0991898720373359 1.0920938100534603 1.11791179396759 1.1350668977522993 1.0359547113062375 1.0118204091849814 0.9508401334872774 1.0 15.320635177534538 -7.678528420656397 2.516596534066422 0.9802898942616607 1.086811910681373 0.4167263221271801 0.05550101931096624 0.2989428998912539 3.7986802274514453 0.033726660728047655 0.016010610912689252 2.0963875861453695e-08 7.678528420656397 0.10652201641971226 S(ph)LPVSICR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLPVSICR 8 0 O94885;A0A087WW74 O94885 SASH1 SAM and SH3 domain-containing protein 1 1 S(1)LPVSICR;S(1)LPVSICR;S(1)LPVSICR 173.39 0.00017352 23588000.0 33204.1 31683.7 30252.1 42025.3 52974.6 41029.6 36537.0 37994.0 49017.2 39526.5 True False 38824.898319131506 34829.04834572143 30973.42479572813 39670.7586888609 42594.60741134798 38877.93554751723 33075.95085502725 36996.69775797056 49733.983818568246 46692.34155839815 0.8315046327366807 0.7459263592972889 0.6633512854991357 0.8496202453082087 0.9122396947703911 0.8326405198354117 0.7083806412591053 0.792350448128603 1.0651422087360067 1.0 15.510898319167945 -8.25643653671113 24.74752771120711 1.0325711205619101 0.7906733330678662 0.6548797155820592 0.06985084909000809 214.26638032996055 1059925.6640266 0.05513816660304393 0.019365291545213385 5.5406850384466024e-09 8.25643653671113 -0.2418977874940439 S(ph)LPVSICR ddPTM_PC-9_Lapatinib_30min_R1 4 SLPVSICR 8 0 O94885;A0A087WW74 O94885 SASH1 SAM and SH3 domain-containing protein 1 1 S(1)LPVSICR;S(1)LPVSICR;S(1)LPVSICR;S(0.995)LPVS(0.005)ICR 160.82 2.7806999999999997e-05 49195700.0 66661.0 63329.0 62659.0 56950.0 73429.0 59766.0 57777.0 62220.0 68253.0 44191.9 True False 65710.40191586969 63182.365591422196 57507.41889073462 61138.29297963079 69110.05058696838 57209.94750135069 60768.41035496778 65110.96834527731 60565.62840404708 51830.41103299462 1.2677962726176188 1.2190211177604025 1.109530442545132 1.1795834098384996 1.3333880478581146 1.1037911211032365 1.1724470083072145 1.256230985778377 1.1685345957509718 1.0 15.661511214385541 -8.556428873663794 20.878988011862646 0.9999999985949357 1.2021216286867935 0.4581650691099508 0.06662433323658129 1264.0572294283813 786650.8515355488 0.06459554299103959 0.016678497510847476 2.7769696055116223e-09 8.556428873663794 0.2021216300918578 S(ph)LPVSVPVWGFK ddPTM_PC-9_AZD4547_30min_R2 4 SLPVSVPVWGFK 12 0 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 S(0.993)LPVS(0.007)VPVWGFK;S(1)LPVSVPVWGFK;S(1)LPVSVPVWGFK;S(0.997)LPVS(0.003)VPVWGFK 168.02 0.00094539 10629500.0 56158.5 45523.9 70065.6 96396.59999999999 89402.4 72036.0 57263.2 77470.20000000001 66584.0 77166.3 True False 74015.73483063505 60238.610406614935 69136.48436395028 74173.85318262372 76990.41995775551 67531.57753233478 62359.51386648252 65498.960678095464 70103.4943060699 74464.73132459384 0.993970346955237 0.8089549150997826 0.9284460325597955 0.9960937461695499 1.0339179177609883 0.9068934558826613 0.8374369014326482 0.8795970859356715 0.9414321794902719 1.0 16.184269664308225 -6.969137932822928 24.999664746915727 0.8999517316040642 0.9479227464510576 0.05810564251540029 0.06897832696442045 519.52868479366 420840.1396252179 0.02552064652162813 0.022506829810463383 1.0736483652509131e-07 6.969137932822928 0.0479710148469934 S(ph)LPVSVPVWGFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 11 SLPVSVPVWGFK 12 0 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 S(1)LPVSVPVWGFK;S(1)LPVSVPVWGFK;S(1)LPVSVPVWGFK;S(1)LPVSVPVWGFK;S(0.991)LPVS(0.009)VPVWGFK;S(1)LPVSVPVWGFK;S(0.993)LPVS(0.007)VPVWGFK;S(0.973)LPVS(0.027)VPVWGFK;S(1)LPVSVPVWGFK;S(0.999)LPVS(0.001)VPVWGFK;S(1)LPVSVPVWGFK 179.67 9.527500000000001e-26 72185310.0 235819.2 214487.69999999998 245989.4 288926.2 369720.5 373635.2 380984.5 379693.5 394792.89999999997 322198.2 True False 275738.73291849263 235780.62135617295 251854.72021599498 272738.6017253783 297276.4220858165 354041.1123648223 344894.89007108257 369726.9479435172 400565.9992877115 380610.18314045144 0.7244649384925692 0.6194805914301195 0.6617130370446669 0.7165825135706715 0.7810522031569412 0.9301934841669102 0.9061630648589627 0.9714058223373436 1.0524311146449175 1.0 18.537954635548743 -6.719979419041163 0.9396766360334117 1.0074751153853019 0.65371015264737 0.932218034688132 0.03798284220360504 0.1288836446368439 0.2466731784367607 0.022347252598832582 0.021454142484358802 1.9055510187602114e-07 6.719979419041163 -0.3537649627379319 S(ph)LPVSVPVWGFK ddPTM_PC-9_Lapatinib_30min_R1 2 SLPVSVPVWGFK 12 0 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 S(1)LPVSVPVWGFK;S(1)LPVSVPVWGFK 207.34 6.0959e-08 8134100.0 82759.0 66318.0 68377.0 76898.0 93009.0 92106.0 82567.0 87600.0 101110.0 77553.0 True False 81578.8414838583 66164.44474556569 62755.30700285285 82553.3354442082 87538.39348272955 88166.84108957274 86841.91525656615 91670.21579952263 89721.92706449823 90957.9327171232 0.8968853957748398 0.727418079644965 0.6899377011790738 0.9075990733094927 0.9624052665639584 0.969314478196963 0.9547481199538939 1.007830906674348 0.9864112385176023 1.0 16.47291184472237 -5.9453459339178245 4.6507419213749515 0.9758319409418296 0.7678822506396513 0.7614985298550743 0.05207850715595025 0.09638435659525853 4.383542412964273 0.0153396672180668 0.022946818125334556 1.1341070915417382e-06 5.9453459339178245 -0.20794969030217825 S(ph)LQEEHVAVAQLR ddPTM_PC-9_AZD4547_30min_R2 3 SLQEEHVAVAQLR 13 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 S(1)LQEEHVAVAQLR;S(1)LQEEHVAVAQLR;S(1)LQEEHVAVAQLR 127.05 6.9065e-05 16006700.0 31087.3 31994.8 48009.0 55727.0 62354.0 47578.0 38197.9 56374.0 44908.0 53289.0 True False 40972.414743990674 42336.49340758509 47372.36929147667 42880.001123567345 53697.22340838592 44602.94013872811 41597.43910086257 47662.693645646345 47281.745198500954 51423.368329909244 0.796766452192125 0.8232928876998713 0.9212226042362067 0.833862162596361 1.0442183223760966 0.8673671443024827 0.8089209332611601 0.9268683712016665 0.91946029079936 1.0 15.650136492126702 -1.5228787452803376 0.06609461825637435 1.101970696799509 0.4243173405680218 0.2979176503891081 0.0661301557166042 419.6079147779424 2.065604497284822 3.9241022604161295 26.767924926620005 0.029999999999999995 1.5228787452803376 -0.6776533562314873 S(ph)LQEEHVAVAQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLQEEHVAVAQLR 13 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 S(1)LQEEHVAVAQLR;S(1)LQEEHVAVAQLR;S(1)LQEEHVAVAQLR 119.04 0.00013261 11688000.0 27734.7 36698.5 39025.9 40596.5 51255.0 39256.8 36180.0 40718.6 33585.3 26238.5 True False 32429.636924705617 40341.68454806279 39956.42546254996 38322.00972062879 41211.95068709611 37198.10430035325 32752.768479483435 39649.7798949229 34076.421475354786 30995.33234614828 1.046274857212027 1.3015406351361791 1.2891110511843005 1.2363800230517927 1.3296179639840975 1.2001195497739443 1.0567000254654004 1.279217769053865 1.0994049392598104 1.0 14.91976335285274 -8.498311776384345 4.09429288009698 1.000410382805086 1.2205763456433132 0.3692989864031432 0.0920426077642719 0.19106817735206558 8.26209711201904 0.08922321470460227 0.02337261163779268 3.1745942377000956e-09 8.498311776384345 0.2201659628382271 S(ph)LQEEHVAVAQLR ddPTM_PC-9_Lapatinib_30min_R1 3 SLQEEHVAVAQLR 13 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 S(1)LQEEHVAVAQLR;S(1)LQEEHVAVAQLR;S(1)LQEEHVAVAQLR 125.39 8.054899999999999e-05 18460000.0 67431.0 58256.0 73853.0 65163.0 58566.0 50055.0 44988.7 45948.0 65296.0 57143.0 True False 66469.42157466916 58121.111811238 67781.09142082426 69955.3043973957 55121.2630251862 47914.26433390407 47317.99475460029 48082.91182142083 57941.676882637454 67020.09141173874 0.9917835111013721 0.8672192261596637 1.01135480410509 1.0437960158488062 0.8224587860757762 0.7149238881150163 0.7060270100782408 0.7174402602052998 0.8645418957529029 1.0 16.032306033850297 -6.410522109494834 5.2315854204524905 0.7762072328676207 0.9718776982168328 0.44171656586289876 0.09399944195266817 0.19342816152017794 7.651536041345411 0.02911934718809316 0.03295423360357679 3.88577715350566e-07 6.410522109494834 0.19567046534921206 S(ph)LQHQEQLEDSK ddPTM_PC-9_Lapatinib_30min_R1 1 SLQHQEQLEDSK 12 0 I3L419;I3L156;Q9BSJ6-2;Q9BSJ6;I3L427 I3L419 FAM64A Protein FAM64A 1 S(1)LQHQEQLEDSK 81.565 0.007404000000000001 2496200.0 13587.0 29466.0 24887.0 28024.0 31635.0 23999.0 29958.0 29589.0 25076.0 25327.0 True False 13393.246888449356 29397.773287385662 22840.88692659812 30084.978445323497 29774.291496803 22972.61871440142 31509.078654380224 30963.81295995519 22251.676818013606 29704.738203893805 0.4508791424626567 0.989666129544683 0.7689307601305186 1.012800659572211 1.0023414881636654 0.7733654663682605 1.0607425131338104 1.0423863273064073 0.7490952004113868 1.0 14.858405453270551 -4.75734194610878 24.99196368138094 0.9330797924678549 0.450878437508147 0.6109064026059023 0.11549136920216022 79.73156598740323 486250.5906816643 0.027718056087144036 0.20782482905336824 1.7484694715676747e-05 4.75734194610878 -0.4822013549597079 S(ph)LQLMDNR ddPTM_PC-9_AZD4547_30min_R2 3 SLQLMDNR 8 0 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 S(1)LQLMDNR;S(1)LQLMDNR;S(1)LQLMDNR 96.82 0.0060027 12274200.0 37152.1 40672.4 56994.0 71217.0 62952.0 46600.0 46824.0 61745.0 41381.1 47878.5 True False 48965.694988314026 53818.95790786831 56238.22232078195 54799.020941681745 54212.20143061727 43686.094633333254 50991.24528989264 52203.72900894797 43568.420464810006 46202.288288081196 1.0598110353972598 1.164854813516931 1.2172172505856105 1.186067248444451 1.1733661565113949 0.9455396313044295 1.1036519440758275 1.1298948806051878 0.9429926975294285 1.0 15.495676686171578 -6.73414270342741 24.990644189064223 1.0374865059322804 1.1651161102811864 0.4953271746648029 0.06783546591439839 201.36541083881488 184353.52819127013 0.022656363054144684 0.022650977527217127 1.844409271086793e-07 6.73414270342741 0.12762960434890602 S(ph)LQLMDNR ddPTM_PC-9_Lapatinib_30min_R1 4 SLQLMDNR 8 0 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 S(1)LQLMDNR;S(1)LQLMDNR;S(1)LQLMDNR;S(1)LQLMDNR 110.64 0.0037588 46871600.0 142357.0 115489.0 123838.0 102079.0 115729.0 102741.0 87975.0 96791.0 118437.0 72322.0 True False 140326.96307492326 115221.59231612307 113656.51766850408 109586.23018556184 108922.04775196822 98347.00693096875 92529.91503501909 101288.26321291771 105097.37786309926 84822.76133699257 1.6543550441304062 1.3583805867667866 1.3399294703099538 1.2919436771244268 1.2841134388354976 1.1594412322919514 1.0908618580266063 1.1941165509869374 1.2390233023133685 1.0 16.37216382902872 -1.5228787452803376 0.3329544478040301 1.113625832582736 6.291021535085781 0.8263170699693756 0.07026591871779991 24.375234581423143 0.34659405784184255 0.06394659048420469 77.8940556491517 0.029999999999999995 1.5228787452803376 5.177395702503045 S(ph)LQLPASPAPDPSPR ddPTM_PC-9_AZD4547_30min_R2 4 SLQLPASPAPDPSPR 15 0 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 S(1)LQLPASPAPDPSPR;S(1)LQLPASPAPDPSPR;S(1)LQLPASPAPDPSPR;S(1)LQLPASPAPDPSPR 163.0 2.4551e-05 34436300.0 68209.3 79425.5 73882.1 82901.9 75154.9 81341.8 61097.1 89715.3 66222.2 71709.2 True False 89898.43855842348 105098.23962469364 72902.3750802935 63790.14777658705 64720.9394030038 76255.48438724589 66534.62353923424 75851.86183750056 69722.57029669917 69198.68273458189 1.2991351136442506 1.5187895993310727 1.053522584525452 0.9218404925605335 0.9352914946552827 1.1019788437264193 0.9615013019024379 1.0961460368897131 1.0075707736247914 1.0 16.07845695454477 -5.3318249753750635 6.0226874166624 1.006734288026631 1.4075526467593489 0.8179966666532983 0.07544358454832678 0.07556828170142915 5.007051298398345 0.019273783591460338 0.04115359971472123 4.657737667663621e-06 5.3318249753750635 0.40081835873271787 S(ph)LQLPASPAPDPSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLQLPASPAPDPSPR 15 0 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 S(1)LQLPASPAPDPSPR;S(1)LQLPASPAPDPSPR 179.66 2.8046999999999998e-05 12216700.0 24744.0 40689.0 31876.0 35071.0 34332.0 23005.0 31415.0 22103.0 22850.6 22152.0 True False 28932.670483723126 44728.335015767036 32636.0447304032 33106.08557171609 27604.89105432415 21798.577302012054 28439.143775095956 21522.819670064328 23184.74679591197 26167.982244864477 1.1056515635400672 1.7092771845083725 1.2471746741882666 1.2651371153468751 1.0549109517124375 0.8330247666034729 1.0867916184358157 0.822486788192782 0.8859967336786935 1.0 14.675515065205728 -6.1947961429144405 1.599364018205627 0.9208191674772402 1.3976768341031367 0.5921882495235702 0.159837299571111 0.24294695827011034 1.235527746396894 0.05455080252343497 0.0780488498292281 6.385631563039977e-07 6.1947961429144405 0.47685766662589646 S(ph)LQLPASPAPDPSPR ddPTM_PC-9_Lapatinib_30min_R1 4 SLQLPASPAPDPSPR 15 0 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 S(0.989)LQLPAS(0.011)PAPDPSPR;S(1)LQLPASPAPDPSPR;S(1)LQLPASPAPDPSPR;S(0.925)LQLPAS(0.069)PAPDPS(0.006)PR 162.26 5.395499999999999e-06 35241600.0 40287.200000000004 82384.0 85711.0 69720.0 90642.0 74683.0 81968.0 86517.0 84044.0 68762.0 True False 39712.69714023233 82193.24490965782 78664.172434028 74847.44137910215 85310.61576902863 71488.98218457605 86211.9019674958 90536.8956658365 74578.07969744525 80647.42008039416 0.4924236522463378 1.0191676910150713 0.9754084179706042 0.9280822784472181 1.0578220070026532 0.8864385508341316 1.0689976428452965 1.1226260626264786 0.9247422871444787 1.0 16.299340761699682 -4.760102708346891 24.99985483516512 0.9996634584581557 0.4924230386882868 0.8279252819046364 0.06916301765341414 13.032031505979353 243647.6769425888 0.017077309245436875 0.10354450239180182 1.7373898966425376e-05 4.760102708346891 -0.507240419769869 S(ph)LQLPASPAPDPSPRPAYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLQLPASPAPDPSPRPAYK 19 1 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 S(0.998)LQLPAS(0.002)PAPDPSPRPAYK;S(0.973)LQLPAS(0.027)PAPDPSPRPAYK 129.2 1.7015999999999998e-05 11715800.0 93878.0 55693.0 80545.0 107699.0 104162.0 96850.0 89907.0 96493.0 88056.0 83532.0 True False 109769.69122498229 61221.83297778552 82465.49826861345 101664.97419486882 83752.20383317363 91771.01550531923 81390.35808968826 93960.16099278469 89343.65241441458 98675.69036105173 1.112428915605636 0.6204348077401481 0.835722536795784 1.030294025031691 0.8487622790043479 0.9300265867867913 0.8248268422737465 0.9522118431498878 0.9054271836103556 1.0 16.590407087176636 -9.768640445421301 0.28402700078621174 1.0421387192781792 0.86606979705225 0.05497012300083193 0.1252356537558832 21.810713665110374 2.3160022455055973 1.0727295199706801 0.1682437203381355 1.7035683174704956e-10 9.768640445421301 -0.1760689222259293 S(ph)LQQLAEER ddPTM_PC-9_AZD4547_30min_R2 3 SLQQLAEER 9 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 1 S(1)LQQLAEER;S(1)LQQLAEER;S(1)LQQLAEER 125.53 0.0014237 58550000.0 13911.599999999999 7041.1 16693.4 16063.0 17505.6 18002.0 12852.1 24654.3 24035.8 14374.400000000001 True False 18335.199420744182 9316.997878784914 16472.03460872621 12359.923520876104 15075.249608651246 16876.332094190246 13995.912002183255 20844.54443445309 25306.283317941758 13871.156631226851 1.3218219581968993 0.6716813980609533 1.1875026031819325 0.8910521198391885 1.0868055209407506 1.2166492342965922 1.0089938693847313 1.5027257631514086 1.824381628059196 1.0 13.759800469775005 -7.763944465962846 24.920379308251054 1.4976654223436456 1.0464311670783635 0.3208498656516169 0.2543161622177624 61.8478325414044 615228.4179082897 0.12311194061307752 0.0634834177444837 1.7220887675773582e-08 7.763944465962846 -0.45123425526528216 S(ph)LQQLAEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SLQQLAEER 9 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 1 S(1)LQQLAEER;S(1)LQQLAEER;S(1)LQQLAEER;S(1)LQQLAEER;S(1)LQQLAEER 124.07 0.0014705999999999999 65200100.0 35760.6 20728.2 39587.200000000004 34916.600000000006 49842.0 29126.3 47503.2 16947.8 22080.5 24040.0 True False 41814.1632759549 22785.958708098566 40531.108983292055 32960.33610314455 40075.81789379072 27598.865554079253 43003.353002614625 16502.938207678424 22403.385540298026 28398.26169946471 1.4724198163418951 0.8023716010944454 1.4272390828786552 1.1606462554630883 1.4112067251829759 0.9718505254354873 1.5142952571433346 0.5811249428689325 0.7888998903309746 1.0 14.793515002437346 -7.768871682771784 24.99953286834704 0.7637592875780239 1.2328231602516762 0.44383263212750756 0.23551085182419335 148.69909750837903 500159.45780838403 0.11601390307234026 0.05747645017477587 1.702661504727722e-08 7.768871682771784 0.46906387267365224 S(ph)LQQLAEER ddPTM_PC-9_Lapatinib_30min_R1 3 SLQQLAEER 9 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 1 S(1)LQQLAEER;S(1)LQQLAEER;S(1)LQQLAEER 158.11 0.0001111 40273000.0 11643.400000000001 15204.6 23337.6 24223.3 21531.6 21683.4 20424.8 20319.5 23347.8 17769.0 True False 11477.362980861948 15169.394682867849 21418.872613741165 26004.762288559963 20265.15362075434 20756.051528474178 21482.296204686052 21263.618149981732 20718.1249007664 20840.34797429577 0.5507279914432325 0.7278858635939089 1.027759835879849 1.247808449294317 0.9723999640384666 0.9959551325186333 1.0308031435550908 1.020310129955988 0.9941352671423663 1.0 14.347091746254147 -5.117112006885434 2.90918525070648 1.0415774196698877 0.5700294733178548 0.8271403471577121 0.07455564645896241 0.1091356647657378 1.6950222194338334 0.02092728301215416 0.08136181911221008 7.636388116172257e-06 5.117112006885434 -0.4715479463520329 S(ph)LQQLDIS(ph)QNSVSYDEKK ddPTM_PC-9_Lapatinib_30min_R1 1 SLQQLDISQNSVSYDEKK 18 1 Q15399 Q15399 TLR1 Toll-like receptor 1 2 S(1)LQQLDIS(0.989)QNS(0.004)VS(0.003)Y(0.003)DEKK 55.208 0.01277 3586200.0 7042.0 8117.4 9017.2 8614.0 8959.0 7667.3 9383.0 8098.9 9704.1 7969.0 True False 6941.579788655365 8098.604659031574 8275.840623398586 9247.502295461625 8432.0492340717 7339.387452349262 9868.805828628398 8475.204460488052 8611.122069296776 9346.431031974964 0.7426984444551732 0.8664916727385602 0.8854546291612495 0.9894153462241475 0.9021678119942164 0.7852609650935819 1.055890295971408 0.9067851066887062 0.92132730021089 1.0 13.190199856569867 -4.425675523262025 1.1756866853835577 0.9306341767568669 0.4985116288882634 0.4148665721063407 0.06915742138750819 3.280344053016801 2.203746651888489 0.020810860317585878 2.125805520537506 3.7525326249509075e-05 4.425675523262025 -0.4321225478686035 S(ph)LQSVAEER ddPTM_PC-9_AZD4547_30min_R2 2 SLQSVAEER 9 0 P61313;A0A2R8YEM3;E7EQV9;E7EX53;A0A2R8Y738;P61313-2 P61313 RPL15 60S ribosomal protein L15;Ribosomal protein L15 1 S(1)LQSVAEER;S(0.997)LQS(0.003)VAEER 86.911 0.011298 9822700.0 6332.1 6268.099999999999 13357.599999999999 21834.0 21598.0 24571.0 15173.9 18883.6 8864.900000000001 16081.7 True False 8345.576084138 8294.140745623792 13180.469496299207 16800.508631937308 18599.49050861722 23034.571485743163 16524.347704260676 15965.57352195919 9333.480515947966 15518.684577888529 0.5377759978464295 0.5344615842918493 0.8493290413982073 1.0825987568479327 1.198522362850155 1.4843121122884015 1.0648033743662169 1.0287968314471319 0.6014350294384215 1.0 13.921718653995562 -5.464082187155292 2.4202815095255685 1.0905644489751833 0.5245467264864077 0.5108955141823965 0.20504079854965385 0.24781281365777386 2.8214005685579684 0.06263051315164567 0.15741059236475477 3.434929381426145e-06 5.464082187155292 -0.5660177224887757 S(ph)LQSVAEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLQSVAEER 9 0 P61313;A0A2R8YEM3;E7EQV9;E7EX53;A0A2R8Y738;P61313-2 P61313 RPL15 60S ribosomal protein L15;Ribosomal protein L15 1 S(0.991)LQS(0.009)VAEER 73.082 0.030551 5400400.0 3330.8 9643.7 12723.0 5766.8 18515.0 18701.0 12370.0 12459.0 6102.0 6133.7 True False 3894.6386537013 10601.06280300703 13026.364572246197 5443.704892217858 14887.118661039589 17720.286638771016 11198.224048955499 12131.964451401678 6191.230206150158 7245.691255657513 0.5375109863617671 1.4630850844948171 1.7978083957241586 0.7513023533768922 2.05461675577407 2.4456309292691474 1.5455011335477213 1.674369500898746 0.8544706071095673 1.0 12.82290761744451 -4.766639405377915 4.48829577105296 1.5697318086803582 0.45519990456314186 0.243727270540671 0.5071795652468857 0.28202544519056766 12.512303514531014 0.129286368202988 1.0126168859772735 1.7114357300703797e-05 4.766639405377915 -1.1145319041172164 S(ph)LQSVAEER ddPTM_PC-9_Lapatinib_30min_R1 1 SLQSVAEER 9 0 P61313;A0A2R8YEM3;E7EQV9;E7EX53;A0A2R8Y738;P61313-2 P61313 RPL15 60S ribosomal protein L15;Ribosomal protein L15 1 S(0.99)LQS(0.01)VAEER 69.229 0.040928 5733600.0 3183.5 3302.1 8048.0 5635.6 9956.4 8030.4 6865.3 7406.4 7113.8 3210.4 True False 3138.1027062176013 3294.454190330421 7386.324506178393 6050.060823810489 9370.784127035544 7686.958511776704 7220.751641829113 7750.528382392511 6312.5689323650195 3765.3133624108937 0.8334240484590915 0.8749482110091932 1.9616759072209067 1.606788131954227 2.488712950317506 2.041518931336652 1.9177027107262425 2.0584019539425324 1.6765055985468214 1.0 11.878554220630626 -5.258790643610153 23.883826167050103 1.90596585828551 0.8541858764283086 0.5326284743787895 0.36718422508239645 80.51779716372793 726012.4019841847 0.08970711305886282 0.21569625831179395 5.510732832699516e-06 5.258790643610153 -1.0517799818572013 S(ph)LQTLPTDSSTFDTDTFCPPRPK ddPTM_PC-9_AZD4547_30min_R2 4 SLQTLPTDSSTFDTDTFCPPRPK 23 1 B0QY95;Q9NQG6 B0QY95 MIEF1 Mitochondrial dynamics protein MID51 1 S(0.985)LQT(0.015)LPTDSSTFDTDTFCPPRPK;S(0.518)LQT(0.477)LPT(0.004)DSSTFDTDTFCPPRPK;S(0.952)LQT(0.014)LPT(0.034)DSSTFDTDTFCPPRPK;S(0.825)LQT(0.144)LPT(0.02)DS(0.003)S(0.003)T(0.003)FDT(0.001)DTFCPPRPK 151.05 6.497500000000001e-09 28905600.0 73307.5 91844.6 108328.9 87408.2 75259.7 93932.9 112024.3 107538.7 91358.1 94234.8 True False 96617.7601092762 121531.57083095657 106892.38800515425 67257.58993322813 64811.18973198358 88059.26091380749 121994.24568017501 90921.06490848747 96187.10265474231 90935.66833484074 1.0624847419992893 1.336456563814503 1.1754726166586045 0.7396172609143217 0.7127147237026692 0.968368765813192 1.3415444996892887 0.9998394092590875 1.057748894532395 1.0 16.47255866336929 -5.551599801146716 24.961938492418955 0.9768098342933815 1.2135942827404826 0.24528976277096914 0.1745444591153734 288.92924575115654 251111.79746394168 0.05235186244295446 0.09067783932929983 2.8080200138430224e-06 5.551599801146716 0.23678444844710111 S(ph)LQTLPTDSSTFDTDTFCPPRPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLQTLPTDSSTFDTDTFCPPRPK 23 1 B0QY95;Q9NQG6 B0QY95 MIEF1 Mitochondrial dynamics protein MID51 1 S(0.97)LQT(0.004)LPT(0.014)DS(0.004)S(0.004)T(0.004)FDTDTFCPPRPK;S(0.926)LQT(0.07)LPT(0.003)DS(0.001)STFDTDTFCPPRPK;S(0.999)LQT(0.001)LPTDSSTFDTDTFCPPRPK;S(0.727)LQT(0.057)LPT(0.214)DS(0.002)STFDTDTFCPPRPK 140.04 9.0893e-09 35846800.0 101732.0 125597.0 102222.0 107334.0 120256.0 84854.0 116904.0 78556.0 83037.0 69936.0 True False 118953.21830141135 138065.44011834415 104659.36015909356 101320.42396152299 96692.70006491894 80404.10686307025 105830.00680833432 76493.98823696208 84251.2590344299 82614.8431869288 1.4398528607294137 1.6711941195113067 1.2668348219494363 1.2264191282463603 1.1704034812017596 0.9732404464067501 1.2810047532121756 0.9259109536028852 1.01980777042448 1.0 16.33411338962447 -5.675659942926792 1.0033561176351222 1.0472514437910445 1.594831849204149 0.7223972517906848 0.11676141420193843 0.347991454426341 0.6338458147048049 0.04372996102863087 0.15094994487668587 2.1102798741679853e-06 5.675659942926792 0.5475804054131046 S(ph)LQTLPTDSSTFDTDTFCPPRPK ddPTM_PC-9_Lapatinib_30min_R1 2 SLQTLPTDSSTFDTDTFCPPRPK 23 1 B0QY95;Q9NQG6 B0QY95 MIEF1 Mitochondrial dynamics protein MID51 1 S(0.321)LQT(0.051)LPT(0.169)DS(0.169)S(0.169)T(0.12)FDTDTFCPPRPK;S(0.999)LQT(0.001)LPTDSSTFDTDTFCPPRPK 133.46 5.5372e-07 13915600.0 18915.9 39165.0 29091.0 32147.0 31127.0 39167.0 38884.0 43163.0 29808.0 32128.0 True False 18646.155797248797 39074.31584879043 26699.250274507427 34511.1976192483 29296.17105803656 37491.91871273638 40897.22325912677 45168.51055427845 26450.70914784455 37681.28199213095 0.49483867882050053 1.036968855171923 0.7085547216807294 0.9158711114567528 0.7774727798314965 0.9949746062399332 1.0853458560053082 1.198698880884973 0.7019588440055808 1.0 15.201560428688765 -6.795815546717784 6.582165377267295 1.0155389210730452 0.8033573649241649 0.2561462908560287 0.17589282916174173 0.2566831721289804 32.34299568458034 0.05873853149489213 0.052708304670944124 1.6002375361954357e-07 6.795815546717784 -0.21218155614888035 S(ph)LQTLPTDSSTFDTDTFCPPRPKPVAR ddPTM_PC-9_AZD4547_30min_R2 2 SLQTLPTDSSTFDTDTFCPPRPKPVAR 27 2 B0QY95;Q9NQG6 B0QY95 MIEF1 Mitochondrial dynamics protein MID51 1 S(0.891)LQT(0.099)LPT(0.006)DS(0.002)S(0.001)TFDTDTFCPPRPKPVAR;S(0.698)LQT(0.301)LPT(0.001)DSSTFDTDTFCPPRPKPVAR 60.541000000000004 0.00060723 43224000.0 88424.0 70436.0 126962.0 176442.0 151915.0 105213.0 105209.0 127166.0 98228.0 131512.0 True False 116540.99266654327 93203.0595489475 125278.40092450294 135766.02290172578 130824.22449377683 98634.01447761552 114572.39718316047 107515.41668397217 103420.13154356362 126907.80490913756 0.9183122562870216 0.7344155043551363 0.9871607267511937 1.0698004192802046 1.0308603524223219 0.7772099954627276 0.9028002435720255 0.8471931002269735 0.81492333444432 1.0 16.953421272988948 -6.7622153198488695 24.999987997086073 0.8610233479075491 0.945168014331907 0.13441691688197432 0.10008929420925092 46.663453991908106 1503417.6363006127 0.03681248535679341 0.03439854325118642 1.7289589421962919e-07 6.7622153198488695 0.08414466642435792 S(ph)LQTLPTDSSTFDTDTFCPPRPKPVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLQTLPTDSSTFDTDTFCPPRPKPVAR 27 2 B0QY95;Q9NQG6 B0QY95 MIEF1 Mitochondrial dynamics protein MID51 1 S(0.966)LQT(0.034)LPTDSSTFDTDTFCPPRPKPVAR;S(0.972)LQT(0.019)LPT(0.001)DS(0.003)S(0.003)T(0.001)FDTDTFCPPRPKPVAR 98.929 6.6066e-10 21771900.0 72705.0 53019.0 57041.0 92405.0 95308.0 100422.0 97579.0 95991.0 97264.0 72636.0 True False 85012.5205107942 58282.37592963587 58401.07376919718 87227.84743105188 76633.08157420272 95155.69353717248 88335.61070921802 93471.33796087145 98686.30199459009 85804.33181374038 0.9907718959380162 0.6792474773435943 0.6806308322051994 1.0165902535130928 0.8931143679383677 1.1089847275278777 1.0295005956222862 1.089354534731116 1.1501319328354334 1.0 16.388762863270152 -6.239383920869731 1.377071582243978 1.0763854581350494 0.7838948777063173 0.5254349641983289 0.1082352334656787 0.3148964520990645 1.2041152483901036 0.04103229420307085 0.05872703016491102 5.762568210967362e-07 6.239383920869731 -0.2924905804287321 S(ph)LQTLPTDSSTFDTDTFCPPRPKPVAR ddPTM_PC-9_Lapatinib_30min_R1 1 SLQTLPTDSSTFDTDTFCPPRPKPVAR 27 2 B0QY95;Q9NQG6 B0QY95 MIEF1 Mitochondrial dynamics protein MID51 1 S(0.897)LQT(0.102)LPTDSSTFDTDTFCPPRPKPVAR 55.406000000000006 0.0012808 21999000.0 134200.0 108670.0 130980.0 100860.0 87706.0 97985.0 68158.0 72245.0 111050.0 80043.0 True False 132286.28339073394 108418.38129166495 120211.32999742124 108277.580859097 82547.30551663053 93794.40996419117 71686.88774034468 75601.76644333931 98542.37959165788 93878.32589940647 1.4091248658660869 1.1548819203256628 1.2805014240052748 1.1533821020106363 0.879300996537609 0.9991061202422249 0.7636148925062788 0.8053165170877561 1.0496819009879776 1.0 16.518504494544757 -6.113134561073048 2.695647959489785 0.900530283661308 1.26934339313889 0.7243410470924476 0.1023344369940007 0.14496842958496142 2.0484590277599417 0.031807132379234 0.04419546446424633 7.706646506274631e-07 6.113134561073048 0.36881310947758195 S(ph)LSAPGNLLTK ddPTM_PC-9_AZD4547_30min_R2 1 SLSAPGNLLTK 11 0 F5GZ00;Q96RR4-6;Q96RR4-5;Q96RR4-2;Q96RR4-3;Q96RR4-4;Q96RR4-7;Q96RR4 F5GZ00 CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 1 S(0.669)LS(0.33)APGNLLTK 119.25 0.00098321 8397800.0 45817.0 30378.0 51476.0 67875.0 40265.0 40128.0 39705.0 47680.0 51879.0 44425.0 True False 60385.85294719776 40197.09442583232 50793.394606179114 52227.46740829636 34674.89977449172 37618.7898164463 43238.668081223026 40312.15157740122 54621.218026922375 42869.69427191763 1.4085907066231242 0.9376575949169754 1.1848322099990345 1.2182841117789045 0.8088441115197311 0.8775147678412297 1.0086068682217568 0.9403414757685417 1.2741219398595698 1.0 15.387670508065169 -4.753424408004849 24.99094086829122 1.0246572718190188 1.4085914106657746 0.3840598997091128 0.1446201787275708 328.4127214113167 1023920.1494576981 0.037214607037171415 0.4008069790510172 1.7643128287524176e-05 4.753424408004849 0.38393413884675587 S(ph)LSAPLHPEFEEVYR ddPTM_PC-9_AZD4547_30min_R2 1 SLSAPLHPEFEEVYR 15 0 Q53HC0-2;Q53HC0 Q53HC0-2 CCDC92 Coiled-coil domain-containing protein 92 1 S(0.5)LS(0.5)APLHPEFEEVYR 83.792 0.0036316000000000005 4944300.0 6490.7 8124.7 10431.0 16457.0 11570.0 11696.0 7388.5 10621.0 8955.8 7910.9 True False 8554.607585053067 10750.850387831984 10292.678124505675 12663.092908115425 9963.705212737355 10964.647271061493 8046.062186578927 8979.768496299885 9429.185304371935 7633.941798890556 1.1206016250079758 1.40829609015285 1.3482783070210878 1.658788243572378 1.3051848540665303 1.4363021830550227 1.0539852671850687 1.1762951215589459 1.2351659932411696 1.0 12.898212472162369 -7.257439101067133 24.992596766822576 1.1310528520594414 1.3887682509755126 0.4619235564804899 0.13859699012545462 327.76354485249317 2047780.3453400633 0.05436049288773795 0.040529170587581105 5.5279091760251326e-08 7.257439101067133 0.2577153989160712 S(ph)LSAPLHPEFEEVYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLSAPLHPEFEEVYR 15 0 Q53HC0-2;Q53HC0 Q53HC0-2 CCDC92 Coiled-coil domain-containing protein 92 1 S(0.5)LS(0.5)APLHPEFEEVYR;S(0.5)LS(0.5)APLHPEFEEVYR;S(0.548)LS(0.452)APLHPEFEEVYR 92.236 0.0020712 12407400.0 52735.0 59000.0 51279.0 59165.0 58900.0 52904.0 52208.0 36177.0 42248.0 45054.0 True False 61661.99393627296 64857.13008258387 52501.685836690434 55850.17686551804 47358.967817187804 50129.62110783072 47262.48028681236 35227.39208269996 42865.79707463648 53221.933552732226 1.1585823704653333 1.2186165693947122 0.9864670885110145 1.049382710047198 0.8898392947385987 0.9418977808869411 0.8880263667982816 0.6618961343784457 0.8054160045156026 1.0 15.699733303969442 -5.836277795414256 0.6798058538638785 0.8165494968639856 1.2354033530676567 0.6395094524922774 0.09297610643031105 0.6523569793286731 0.533021833229172 0.05212859491898272 0.17487961955083725 1.4578814316370276e-06 5.836277795414256 0.4188538562036711 S(ph)LSAPLHPEFEEVYR ddPTM_PC-9_Lapatinib_30min_R1 3 SLSAPLHPEFEEVYR 15 0 Q53HC0-2;Q53HC0 Q53HC0-2 CCDC92 Coiled-coil domain-containing protein 92 1 S(0.544)LS(0.456)APLHPEFEEVYR;S(0.559)LS(0.441)APLHPEFEEVYR;S(0.567)LS(0.433)APLHPEFEEVYR 125.45 1.4952e-05 13629700.0 77973.0 58556.0 76127.0 53519.0 67439.0 75328.0 72357.0 76813.0 76598.0 77969.0 True False 76861.0907215029 58420.41717966994 69868.13191871799 57454.9657941503 63472.37061017528 72106.39703814447 76103.29141448 80382.01239964309 67970.7266273013 91445.83776283816 0.8405094491106273 0.638852665237552 0.7640384038026832 0.628295034522598 0.6940979727780376 0.7885148061648262 0.8322225841689093 0.8790122586892501 0.7432894518784025 1.0 16.480629885493173 -7.035345042972205 2.439047770317598 0.8551053950482336 0.7074270604169421 0.42617670952961995 0.08178851476801946 0.29220064696019854 3.4616022435387093 0.032943532677193195 0.025563190516852862 9.218387437332934e-08 7.035345042972205 -0.14767833463129143 S(ph)LSDIK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSDIK 6 0 O14545;F8VNX8 O14545 TRAFD1 TRAF-type zinc finger domain-containing protein 1 1 S(1)LSDIK 96.19 0.034612000000000004 8715600.0 41629.0 70806.0 60028.0 58351.0 70375.0 67229.0 69115.0 58512.0 70943.0 60745.0 True False 41035.362826176344 70642.05305730758 55092.72955478093 62642.3271932298 66235.68086257344 64353.7723884534 72693.4365177078 61230.681128557844 62952.65227709123 71244.69231237535 0.5759778236707805 0.9915412750689486 0.7732888972728599 0.8792560562767523 0.9296928474637846 0.903278129215459 1.020334766819967 0.8594420039052081 0.8836118205279444 1.0 16.120494917786576 -4.75263778081825 24.9970192501931 0.9089571914139206 0.5759771896755933 0.6725141927647383 0.07096360228596997 203.23037390527824 577142.495064263 0.01733797819586661 0.20222870516196037 1.767511382152017e-05 4.75263778081825 -0.3329800017383273 S(ph)LSDSESDDSK ddPTM_PC-9_AZD4547_30min_R2 5 SLSDSESDDSK 11 0 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 S(0.985)LS(0.013)DS(0.002)ESDDSK;S(0.995)LS(0.003)DS(0.002)ESDDSK;S(0.999)LS(0.001)DSESDDSK;S(0.999)LS(0.001)DSESDDSK;S(0.812)LS(0.069)DS(0.101)ES(0.003)DDS(0.015)K 212.68 2.192e-07 367285200.0 256999.0 300240.0 258882.0 292942.0 296066.0 330622.0 318589.0 303197.0 312638.0 295394.0 True False 338719.33608871914 397286.708486796 255449.0555295063 225408.7478087831 254962.346371158 309948.15407429053 346942.8038113274 256344.8704239375 329163.4064168728 285052.3459709355 1.1882706487995565 1.3937324638868405 0.8961478799951795 0.7907626476147867 0.8944404421676098 1.0873376713268428 1.2171196228172856 0.8992905129434541 1.154747228252719 1.0 18.12086734928687 -5.262510550210488 24.999911989958218 0.9895888873865217 1.2910015652019498 0.44844062374603944 0.13239643530266632 84.58584466973579 1974194.2455099695 0.03664129976384327 0.08395512540284374 5.463732768071735e-06 5.262510550210488 0.301412677815428 S(ph)LSDSESDDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SLSDSESDDSK 11 0 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 S(0.465)LS(0.465)DS(0.07)ESDDSK;S(0.987)LSDS(0.012)ESDDSK;S(0.856)LS(0.06)DS(0.074)ES(0.01)DDSK;S(0.6)LS(0.373)DS(0.027)ESDDSK;S(0.995)LS(0.005)DSESDDSK;S(0.965)LS(0.035)DSESDDSK 210.44 2.1402000000000003e-06 491058000.0 1120073.0 1444209.0 1139278.0 1348974.0 1436055.0 1099729.0 1403465.0 1193016.0 1145329.0 1040105.0 True False 1309679.2364498517 1587580.5250752266 1166442.7082558733 1273395.3602127186 1154670.3315570753 1042057.275277741 1270518.6349933196 1161700.594104941 1162077.2698754123 1228667.803033348 1.065934366650206 1.2921153473345612 0.9493556398044674 1.0364032955604003 0.9397742243317625 0.8481196241206118 1.0340619586975828 0.9454960822094649 0.9458026547179504 1.0 20.228663473887828 -5.279026349696903 24.93330927649124 0.9607462606375753 1.179024853749008 0.5911287874768486 0.07206189927397476 435.6773436888988 617665.9543919906 0.018092359748697672 0.037798417745335815 5.259853526187161e-06 5.279026349696903 0.21827859311143272 S(ph)LSDSESDDSK ddPTM_PC-9_Lapatinib_30min_R1 4 SLSDSESDDSK 11 0 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 S(0.99)LS(0.01)DSESDDSK;S(0.71)LS(0.287)DS(0.003)ESDDSK;S(0.673)LS(0.325)DS(0.002)ESDDSK;S(0.426)LS(0.024)DS(0.426)ES(0.123)DDSK 227.48 2.3358e-13 766910000.0 1013683.0 1234554.0 1143387.0 1101100.0 1368555.0 1241935.0 1153903.0 1333856.0 1260478.0 1243702.0 True False 999227.6945333059 1231695.466063774 1049382.1344614571 1182078.5671619212 1288059.2855826523 1188820.3351418872 1213646.4512492577 1395831.81924073 1118509.6942182237 1458674.2335712565 0.6850245733668082 0.8443937910990771 0.7194081518066348 0.8103787260763844 0.8830342347441831 0.8150005722876938 0.8320202162465707 0.9569181295698422 0.7667988290159814 1.0 20.476226290765076 -3.121108066816152 0.044455671809887486 1.3980607829747984 4.0598288629794007e-13 0.5114485566200084 0.06476956422149109 371.8116868017723 1.6983169454041722 16.109911621499915 42.90849136579227 0.0007566445934197969 3.121108066816152 -1.3980607829743925 S(ph)LSDSESDDSKSK ddPTM_PC-9_AZD4547_30min_R2 4 SLSDSESDDSKSK 13 1 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 S(0.967)LS(0.021)DS(0.012)ESDDSKSK;S(0.999)LS(0.001)DSESDDSKSK;S(0.874)LS(0.049)DS(0.077)ESDDSKSK;S(0.994)LS(0.006)DSESDDSKSK 154.13 0.00064841 78936000.0 230149.0 133075.0 221003.0 400021.0 377927.0 278737.0 189604.0 221762.0 188943.0 255045.0 True False 303331.59460341424 176088.89132654024 218072.35581920494 307802.3387128417 325458.3595448739 261307.5313264254 206478.3886883822 187493.77848380175 198930.14124522038 246115.95217965622 1.2324743354384138 0.7154712637155732 0.886055348659479 1.2506395298105526 1.3223781581914706 1.0617252925388594 0.83894760522333 0.7618107514905726 0.8082781285952899 1.0 17.908978644563753 -7.259601425292665 6.582998494615077 0.8316509163035348 1.0722940950162825 0.27642164909294364 0.17771488188460374 0.20684526423812155 51.94070104939924 0.07842855005278757 0.05664423517814167 5.5004544769381475e-08 7.259601425292665 0.24064317871274765 S(ph)LSDSESDDSKSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLSDSESDDSKSK 13 1 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 S(0.875)LS(0.092)DS(0.026)ES(0.007)DDSKSK;S(0.981)LS(0.019)DSESDDSKSK;S(0.934)LS(0.06)DS(0.006)ESDDSKSK 168.0 0.00049567 7203000.0 25175.699999999997 9222.2 13413.5 34383.3 35220.0 45650.0 40142.0 43881.0 50105.0 42708.2 True False 29437.44876725946 10137.719068603483 13733.328710982032 32456.91517316263 28318.893828885455 43256.03363776788 36339.45915708744 42729.17024576267 50837.69083565288 50450.8585820748 0.5834875677956963 0.2009424488209883 0.2722119919652168 0.6433372213152896 0.5613163903408209 0.857389444966488 0.720294167005492 0.8469463443570483 1.0076675058552031 1.0 15.622591201141963 -6.605530200977145 0.6754471652844429 0.9619276513270816 0.31523434292272534 0.7535668865477103 0.13041097059489049 0.3738356460807392 0.3790220638843342 0.09468843805711136 0.11666937387696578 2.4801034645081274e-07 6.605530200977145 -0.6466933084043562 S(ph)LSDSESDDSKSK ddPTM_PC-9_Lapatinib_30min_R1 2 SLSDSESDDSKSK 13 1 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 S(0.983)LS(0.016)DS(0.001)ESDDSKSK;S(0.991)LS(0.009)DSESDDSKSK 193.45 6.9439e-06 198984000.0 171377.0 65520.0 88654.0 81411.0 77451.0 79400.0 56781.0 51921.0 93853.0 56237.0 True False 168933.1325533074 65368.29246553677 81365.21033433636 87398.23651913463 72895.48445452479 76004.24709044024 59720.84234843324 54333.43920692936 83282.28682409598 65957.49051890781 2.5612425703928183 0.9910670031752931 1.2336007585220614 1.325069159416859 1.105188870604895 1.1523216922367954 0.9054444291101897 0.8237645001268472 1.2626660924921291 1.0 16.009248889228424 -4.759049745812809 24.99999698504784 1.0919610857988677 2.561244485238134 0.893442142348583 0.15254978105116043 20.2180958613532 211472.84534542443 0.040403238327882854 0.264005210724452 1.7416073713486616e-05 4.759049745812809 1.4692833994392662 S(ph)LSELCLAVPAPGIR ddPTM_PC-9_AZD4547_30min_R2 2 SLSELCLAVPAPGIR 15 0 A0A5F9ZHW8;O94827-5;O94827-3;O94827;O94827-7;O94827-2;O94827-6 A0A5F9ZHW8 PLEKHG5 Pleckstrin homology domain-containing family G member 5 1 S(0.5)LS(0.5)ELCLAVPAPGIR;S(0.957)LS(0.043)ELCLAVPAPGIR 163.27 0.00028463 11528800.0 16069.0 13106.8 20625.5 34299.0 22559.0 24518.0 19692.8 25507.0 21122.0 20335.1 True False 21178.607744036508 17343.31678255643 20351.9923935377 26391.895464267523 19427.072246684682 22984.885584121555 21445.421049991415 21565.47924254978 22238.465798582354 19623.17433852272 1.0792651269708327 0.8838181062535511 1.0371406808318582 1.3449350756904281 0.9900066070629019 1.1713133251330994 1.092861974318365 1.098980158384165 1.1332756573907359 1.0 14.2602708172338 -5.529098985651403 24.99500170244605 1.124206004446092 0.976276018513573 0.2297172488488768 0.1025832854282243 183.45628874792308 737185.7016107724 0.02610930203154743 0.0453779560281502 2.957338344642122e-06 5.529098985651403 -0.14792998593251894 S(ph)LSELESLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSELESLK 9 0 P22059 P22059 OSBP Oxysterol-binding protein 1 1 S(0.617)LS(0.383)ELESLK 81.771 0.035563 0.0 8743.5 10682.0 10173.0 10484.0 12101.0 7796.9 9663.5 7613.7 7860.4 7563.5 True False 10223.601858003274 11742.438365121374 10415.56290131735 9896.615469586597 9729.895917755339 7388.0168383420005 8748.103322318633 7413.848442381971 7975.343479584183 8934.702677366946 1.1442576465248608 1.3142506011830566 1.1657425297096526 1.1076603024134573 1.089000526274114 0.8268900606012384 0.9791152138144452 0.8297812148984491 0.8926255039003171 1.0 13.12520400575591 -6.347563297630615 1.3789864585609246 0.8971401540482731 1.2198344177431721 0.7552970330091411 0.07424246416618877 0.18592083417312666 0.7163374311564055 0.028048287069691924 0.03641221421519568 4.49196850275329e-07 6.347563297630615 0.32269426369489906 S(ph)LSEQPVMDTATATEQAK ddPTM_PC-9_AZD4547_30min_R2 1 SLSEQPVMDTATATEQAK 18 0 P18615;P18615-3;A0A0A0MT02;P18615-4;A2ABK4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 1 S(0.392)LS(0.392)EQPVMDT(0.215)AT(0.002)ATEQAK 111.33 0.00018017 30397000.0 51369.0 52353.0 72724.0 96455.0 76295.0 73917.0 84527.0 100820.0 95420.0 71136.0 True False 67703.27345842378 69275.0834312858 71759.63224298251 74218.78996489481 65702.75619756218 69294.95830498042 92049.73924950353 85240.58561312061 100463.70639620902 68645.55029211326 0.9862733006046316 1.0091707785354425 1.045364658562975 1.0811886516906817 0.957130592120999 1.0094603074795625 1.3409425499219751 1.2417496145109055 1.4635137451545985 1.0 16.066878585288755 -7.254354582752257 24.529546685504894 1.2816972813143106 1.0163008747588844 0.532141298100718 0.11272619451987785 296.9060951923316 1027974.3194681775 0.04085296698340249 0.030942951873461837 5.567310164094621e-08 7.254354582752257 -0.2653964065554262 S(ph)LSEQPVMDTATATEQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSEQPVMDTATATEQAK 18 0 P18615;P18615-3;A0A0A0MT02;P18615-4;A2ABK4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 1 S(0.54)LS(0.436)EQPVMDT(0.022)AT(0.001)ATEQAK 71.263 0.0080981 5795500.0 13528.0 13405.0 10666.0 13607.0 17705.0 19480.0 20284.0 22078.0 22068.0 14271.0 True False 15818.02320982082 14735.759809441315 10920.317891030261 12844.643904489207 14235.832346405938 18458.4345074199 18362.552676557258 21498.475893574632 22390.702751445704 16858.219330826167 0.9382973906915962 0.8740994241601888 0.6477741021592873 0.7619217458514186 0.8444446039668583 1.0949219573663782 1.0892344153442313 1.2752518799102053 1.3281772120797535 1.0 14.041164537522409 -6.8834843807043065 1.8859835926972672 1.2019856567324763 0.7955394313770455 0.7077830379656596 0.11116704856650922 0.18442403880684813 1.3433617094310637 0.04964343875663867 0.04162205225146874 1.307722569999496e-07 6.8834843807043065 -0.40644622535543073 S(ph)LSEQPVMDTATATEQAK ddPTM_PC-9_Lapatinib_30min_R1 3 SLSEQPVMDTATATEQAK 18 0 P18615;P18615-3;A0A0A0MT02;P18615-4;A2ABK4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 1 S(0.706)LS(0.272)EQPVMDT(0.02)AT(0.001)ATEQAK;S(0.928)LS(0.068)EQPVMDT(0.004)ATATEQAK;S(0.763)LS(0.195)EQPVMDT(0.042)AT(0.001)ATEQAK 138.55 3.3672e-08 17252600.0 70870.0 63169.0 56885.0 44413.2 90080.0 81732.0 105788.0 90195.0 90896.0 108796.0 True False 69859.38080403356 63022.73606159176 52208.13488245004 47679.494886091976 84781.67150409409 78236.51288659757 111265.1850153407 94385.78897303583 80658.33530268651 127601.24363844261 0.5474819744075513 0.4939037760491294 0.4091506743490799 0.37366011119132625 0.6644266865009754 0.6131328398983342 0.8719757099751313 0.7396933312066881 0.6321124544148757 1.0 16.961282864529174 -6.703504309503455 1.6527179208671954 0.7838920942578994 0.4592086758400615 0.6482757881106751 0.11072473818303916 0.23996386190643518 1.357050308120091 0.04589246238226755 0.04372238926799046 1.9792273812699691e-07 6.703504309503455 -0.32468341841783793 S(ph)LSFSGPR ddPTM_PC-9_AZD4547_30min_R2 1 SLSFSGPR 8 0 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 S(0.81)LS(0.166)FS(0.024)GPR 103.55 0.0039391 2733700.0 11802.0 12257.0 20316.0 23876.0 21280.0 15360.0 15415.0 26829.0 17328.0 18520.0 True False 15554.790503150092 16218.835551301167 20046.596565761414 18371.757080522802 18325.639319537677 14399.536771845458 16786.905137188092 22683.194519087614 18243.922704186865 17871.620437049285 0.8703626264859441 0.9075190248377386 1.1216999956088611 1.0279849633800802 1.0254044608930466 0.8057208255158597 0.9393051512210672 1.2692298719630122 1.020832037500403 1.0 14.125382830409364 -7.701447155500451 24.999815227482753 1.1087790464013392 0.9608582029162671 0.25979171756692565 0.10743426185276786 93.26789165314216 38865.88685178339 0.052095441522682064 0.03007729483824942 1.98862476946342e-08 7.701447155500451 -0.14792084348507206 S(ph)LSGS(ph)SPCPK ddPTM_PC-9_AZD4547_30min_R2 1 SLSGSSPCPK 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 S(0.999)LS(0.112)GS(0.54)S(0.348)PCPK 115.29 0.013771 9831900.0 43675.0 39125.0 51931.0 70718.0 61022.0 60939.0 54311.0 60639.0 50566.0 59703.0 True False 57562.741503565485 51771.391118924555 51242.361008887354 54415.057682208535 52550.14861639225 57128.47469658142 59144.57378565178 51268.635895596344 53238.81552746497 57612.81614217886 0.9991308420249793 0.8986089308872068 0.889426423496288 0.9444957099115101 0.9121260187439408 0.9915931648888302 1.026587098948484 0.8898824832494538 0.9240793818528227 1.0 15.814102158718052 -6.747123950532512 24.991088137453893 0.9633060028365935 0.9257719340142122 0.14092490482640718 0.04588899620153951 519.3803003418691 906704.2064972692 0.01584459087612452 0.015774628469477518 1.790094876141548e-07 6.747123950532512 -0.037534068822381306 S(ph)LSGS(ph)SPCPK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSGSSPCPK 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 S(1)LS(0.245)GS(0.453)S(0.302)PCPK 105.2 0.030216000000000003 12525000.0 62954.0 77436.0 74941.0 77795.0 83480.0 85482.0 83738.0 80913.0 81313.0 65043.0 True False 62056.26441565034 77256.7016996535 68779.64026062569 83516.30381651218 78569.87052799478 81826.13412827457 88073.54390681919 84672.513367429 72154.67367615005 76285.59588565027 0.8134728934761255 1.012729871251958 0.901607170555818 1.0947847080030746 1.0299437215613885 1.0726288911858195 1.1545239030293306 1.1099410365011824 0.9458492502871402 1.0 16.21912305513993 -3.6782602785834095 0.6612105536738273 1.0669805556681555 4.774862028092064e-13 0.4855561646277312 0.07058703226939975 9.978217528519385 1.0920767381287935 0.029565752946959865 11.195890785911972 0.00020976823373046214 3.6782602785834095 -1.0669805556676781 S(ph)LSGSPLK ddPTM_PC-9_AZD4547_30min_R2 1 SLSGSPLK 8 0 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 S(0.426)LS(0.283)GS(0.291)PLK 101.46 0.0045792 32436000.0 161680.0 185070.0 227970.0 204140.0 225650.0 198380.0 154550.0 203360.0 187790.0 203770.0 True False 213090.876847086 244890.25825889758 224946.96884704803 157078.6769315601 194322.3925025226 185975.26723949893 168304.650596978 171935.38474790895 197716.1960191165 196636.0743227609 1.0836815044289179 1.245398430081205 1.143976097070659 0.7988293982808526 0.9882336858676267 0.9457840728361817 0.8559195009188428 0.8743837331988843 1.0054929986782724 1.0 17.585168493329498 -5.670959022241112 7.320060956732928 0.9199609483242323 1.1705762631101575 0.6819595910971494 0.0730372651226595 0.11748740502859943 8.121595550407411 0.019081319969876637 0.033146428463027566 2.1332461856185355e-06 5.670959022241112 0.25061531478592525 S(ph)LSGSPLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSGSPLK 8 0 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 S(0.835)LS(0.014)GS(0.151)PLK 99.01299999999999 0.0053299 69426000.0 305920.0 287910.0 279410.0 396020.0 432440.0 295200.0 304350.0 354840.0 316550.0 262240.0 True False 357706.21380458196 316491.80206909776 286072.19406832627 373832.2833141627 347706.48629651446 279719.1923301003 275519.76469681517 345525.8259840571 321178.94489623664 309782.0361093016 1.1547028946454825 1.0216596354135548 0.9234628245757617 1.2067590748943944 1.1224230128496921 0.9029548512341944 0.8893987790809227 1.1153836753211341 1.036790089348221 1.0 18.240893960825616 -6.742641597584597 24.99820466147367 0.9898977546277588 1.0799391003961376 0.21108226193818225 0.09330913148100357 467.3798741427304 621543.48935777 0.03309116760120261 0.033037201230617264 1.8086661157285076e-07 6.742641597584597 0.09004134576837886 S(ph)LSGSS(ph)PCPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSGSSPCPK 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 S(0.867)LS(0.133)GS(0.024)S(0.976)PCPK 102.53 0.038528 5340200.0 50939.0 66269.0 58289.0 65498.0 80736.0 73814.0 80460.0 76044.0 62711.0 60354.0 True False 59561.96660888986 72847.74836343656 59678.83082226348 61828.35940738105 64916.360368225345 69943.06389787946 72838.24632004538 74047.92557527815 63628.02973744385 71295.702437999 0.8354215551868197 1.0217691371620508 0.8370607032613513 0.8672101864926424 0.9105227685312262 0.9810277689416717 1.0216358606381335 1.0386029317780068 0.8924525260519987 1.0 16.121527496074897 -6.749471504215088 3.921134886489862 0.9926170410471447 0.895303959446127 0.3682620080230803 0.06069545875341715 0.24240790230102904 8.211367736060808 0.02117931425613731 0.019956415746796446 1.780444727067343e-07 6.749471504215088 -0.0973130816010177 S(ph)LSGSS(ph)PCPK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSGSSPCPK 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 S(0.996)LS(0.004)GS(0.226)S(0.774)PCPK 129.74 0.0028616999999999996 11893000.0 69561.0 63009.0 76627.0 68728.0 81660.0 84753.0 73693.0 77421.0 87273.0 62885.0 True False 68569.04738407487 62863.10653176143 70327.023848774 73782.48638988697 76856.91934973712 81128.31175889273 77508.46295738172 81018.26229925599 77443.39571456771 73754.58846100456 0.9296919529329164 0.8523280767134689 0.9535274389871651 1.0003782534682186 1.0420628865738002 1.0999764686069233 1.0508968265528578 1.0984843653773742 1.050014613741808 1.0 16.17044518544033 -5.814804401939758 1.5808835889571302 1.064806309110558 0.8896917589519888 0.7954221412183664 0.033503182645809655 0.14807654566277217 0.7526966036717617 0.010347487644194634 0.021538361330763048 1.5317771899648936e-06 5.814804401939758 -0.17511455015856914 S(ph)LSGSSPCPK ddPTM_PC-9_AZD4547_30min_R2 3 SLSGSSPCPK 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.999)LS(0.001)GSSPCPK;S(0.998)LS(0.001)GS(0.002)SPCPK;S(0.998)LS(0.002)GSSPCPK 138.99 0.00012025 184758100.0 128876.0 105706.0 128756.0 179601.0 168558.0 142376.0 107173.0 149080.0 120947.0 144571.0 True False 169855.88721267364 139873.3973065057 127048.61131232411 138196.7642577891 145156.6312228681 133473.20621277794 116711.18937838863 126043.1115175962 127340.01150180583 139509.6132939877 1.2175210238360954 1.0026075910034344 0.9106799761862675 0.9905895442959042 1.0404776258463313 0.9567312464088816 0.8365816994449258 0.9034725890321721 0.9127687224927149 1.0 17.090005012790265 -4.773522082555813 2.9437865820105995 0.9423456260270093 1.2673444805809737 0.689710883595575 0.05494854490755609 0.2530717799565157 3.078432171762566 0.015599067573905495 0.19996511243999052 1.684526771524593e-05 4.773522082555813 0.3249988545539644 S(ph)LSGSSPCPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLSGSSPCPK 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.865)LS(0.135)GS(0.001)SPCPK;S(0.981)LS(0.017)GS(0.001)SPCPK;S(1)LSGSSPCPK 137.89 0.00011814 107425400.0 122257.0 123521.7 106225.2 124278.0 130098.0 118095.0 125745.0 131663.0 110798.0 93329.0 True False 142952.6954141826 135784.11804952403 108758.01162931426 117315.10657471254 104606.23081630704 111901.89030563405 113833.52328503731 128206.98575847968 112418.21114077767 110248.80890804224 1.2966370959473899 1.2316152835971281 0.9864778831309512 1.064094095316388 0.9488196004326757 1.0149940975686245 1.0325147673929527 1.162887717593541 1.0196773303423614 1.0 16.750403543899942 -5.154954453414441 4.340780523366426 1.032741301931579 1.281470343962797 0.7524088160502438 0.054357081627087946 0.1106281875849324 3.439278152218477 0.014704002224865521 0.04346646749357663 6.999153957027084e-06 5.154954453414441 0.24872904203121804 S(ph)LSGSSPCPK ddPTM_PC-9_Lapatinib_30min_R1 4 SLSGSSPCPK 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.969)LS(0.021)GS(0.01)S(0.001)PCPK;S(0.994)LS(0.005)GS(0.001)SPCPK;S(0.793)LS(0.087)GS(0.012)S(0.108)PCPK;S(0.81)LS(0.121)GS(0.067)S(0.002)PCPK 115.29 0.0011368 161413800.0 136342.0 134206.0 141958.0 110043.0 139790.0 147954.0 131887.0 145284.0 155558.0 131104.0 True False 134397.7380779391 133895.2542525922 130286.76121372655 118135.92931268676 131567.82703771413 141626.3523176194 138715.4635319528 152034.4250253176 138037.41994163982 153765.1517149008 0.8740454945677729 0.870777629126593 0.8473100683781327 0.7682880548365411 0.8556413827865029 0.9210562389338502 0.9021254945278371 0.9887443502621962 0.8977158894726543 1.0 17.230369052218293 -6.9113322888223845 2.022045471799619 0.9474109289811895 0.8397421400581333 0.6053269552549069 0.04042025492284502 0.23781466498438222 1.9812250946206706 0.017565250138910936 0.014539078733107178 1.2265004480050517e-07 6.9113322888223845 -0.1076687889230562 S(ph)LSGTGR ddPTM_PC-9_Lapatinib_30min_R1 2 SLSGTGR 7 0 Q6ICG6-2;B0QY16;Q6ICG6-3;Q6ICG6 Q6ICG6-2 KIAA0930 Uncharacterized protein KIAA0930 1 S(0.997)LS(0.003)GTGR;S(0.998)LS(0.002)GTGR 83.647 0.020712 9763800.0 17855.2 18416.2 26017.1 20275.4 19326.0 16228.0 18187.4 15007.800000000001 23632.0 20999.2 True False 17600.581573757343 18373.558420387966 23878.074466910282 21766.52055275164 18189.282676377887 15533.966269315659 19129.054580368353 15705.117176667522 20970.315304007723 24628.88374032484 0.7146317210040638 0.7460166938181191 0.9695150912509584 0.8837802306530582 0.7385345949153431 0.6307214907950504 0.7766919029727838 0.6376706854543128 0.8514521212211114 1.0 14.58806362132088 -1.5395239329239492 23.620729245275818 0.7841659523919683 0.003970046519127912 0.0 0.12199327679263355 0.0 0.0 0.028315519740387835 0.0 0.028871946684534727 1.5395239329239492 -0.7801959058728404 S(ph)LSIEIGHEVK ddPTM_PC-9_AZD4547_30min_R2 1 SLSIEIGHEVK 11 0 A0A3B3IU16;C9JTT8;Q68DU7;H7C1N3;O15155-2;O15155 A0A3B3IU16 BET1;DKFZp781C0425 BET1 homolog 1 S(0.54)LS(0.46)IEIGHEVK 77.062 0.011289 6504600.0 51525.0 67275.0 84452.0 110880.0 82014.0 83733.0 74760.0 89755.0 79457.0 62282.0 True False 67908.87821342226 89020.32811567157 83332.11130004341 85318.32907892311 70627.77176468808 78497.16227323815 81413.49517068984 75885.4271147158 83656.93480531953 60101.52613716537 1.1299027259048087 1.4811658511384038 1.3865223839717573 1.4195700935148843 1.1751410705195642 1.3060760236618576 1.3545994653261502 1.2626206353151161 1.3919269639575433 1.0 15.875114004804809 -11.186200283414124 2.770846339079208 0.9619059381086358 1.3267138584255935 0.4663957876562128 0.10359918475023691 18739752.58037307 17305879.497474357 5069226.9435536675 0.025559993446522808 6.513279521352378e-12 11.186200283414124 0.36480792031695775 S(ph)LSIEIGHEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSIEIGHEVK 11 0 A0A3B3IU16;C9JTT8;Q68DU7;H7C1N3;O15155-2;O15155 A0A3B3IU16 BET1;DKFZp781C0425 BET1 homolog 1 S(0.577)LS(0.423)IEIGHEVK 78.985 0.018465000000000002 0.0 102430.0 95000.0 83608.0 99176.0 134510.0 81949.0 102450.0 66737.0 74140.0 77685.0 True False 119769.3759152829 104430.97216687257 85601.5318051059 93619.49025293044 108153.73108811447 77651.45017703048 92745.19432623195 64985.22446369647 75224.1572409001 91768.67554587846 1.3051226380117678 1.1379805968177428 0.9327968535659057 1.0201682621661756 1.1785473686393624 0.8461650962610845 1.0106410904869745 0.7081416842635809 0.8197149712953287 1.0 16.485714165578166 -1.5228787452803383 0.3385688674005142 0.8632564441068878 5.478414812660159 0.5126939738351872 0.11892617070933251 49.989299091216296 0.7089000166916176 0.10895270580569022 145.62732059250789 0.02999999999999995 1.5228787452803383 4.615158368553271 S(ph)LSIEIGHEVK ddPTM_PC-9_Lapatinib_30min_R1 2 SLSIEIGHEVK 11 0 A0A3B3IU16;C9JTT8;Q68DU7;H7C1N3;O15155-2;O15155 A0A3B3IU16 BET1;DKFZp781C0425 BET1 homolog 1 S(0.583)LS(0.417)IEIGHEVK;S(0.5)LS(0.5)IEIGHEVK 96.135 0.0033607 9531500.0 167700.0 186142.0 119984.0 83434.0 121162.0 141757.0 142089.0 140181.0 172677.0 83548.0 True False 165308.56724758638 185710.99963553046 110119.37867163365 89570.01468766497 114035.4893736572 135694.383561707 149445.6731731833 146694.32101590047 153228.29789057805 97989.16047928785 1.6870087103412623 1.8952198256131048 1.1237914288990136 0.9140808457747481 1.163756162578422 1.3847897348849008 1.5251245386960115 1.4970464110355095 1.563727019816301 1.0 16.58033454727029 -5.257442087657856 24.997906679746066 1.285776644041965 1.7911143037848676 0.47710361767544895 0.21716643571020358 323.6233585639305 2023826.4198246333 0.062424847384010836 0.15277298350223173 5.52787116139178e-06 5.257442087657856 0.5053376597429027 S(ph)LSLESTDR ddPTM_PC-9_AZD4547_30min_R2 2 SLSLESTDR 9 0 H0Y7V8;A0A0A0MRJ1;H0Y5V1;A0A0A0MRJ0;Q5VT25-3;Q5VT25-4;Q5VT25-5;Q5VT25;Q5VT25-2;Q5VT25-6 H0Y7V8 CDC42BPA Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase MRCK alpha 1 S(0.999)LS(0.001)LESTDR;S(0.997)LS(0.003)LESTDR 112.85 0.0021408 6739700.0 61836.0 55809.0 79307.0 110437.0 95639.0 86743.0 76992.0 101010.0 82529.0 76601.0 True False 81498.56173129889 73848.1678455223 78255.33736172678 84977.4558846414 82361.1756993074 81318.94649740835 83844.13884673259 85401.22547888642 86891.31445370731 73919.22230552969 1.102535432454113 0.9990387553089547 1.0586601823037944 1.14959888962853 1.114205116483567 1.1001055471240409 1.1342670584409063 1.1553317637176737 1.1754901058693525 1.0 16.173661957977423 -5.669675631120635 6.08754280130202 1.1244767791319437 1.0459744493790595 0.24823179974751786 0.0509225501528604 0.23867306367202995 12.888497370071542 0.013192547790022224 0.023006898004652294 2.1395595019474684e-06 5.669675631120635 -0.07850232975288418 S(ph)LSLESTDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSLESTDR 9 0 H0Y7V8;A0A0A0MRJ1;H0Y5V1;A0A0A0MRJ0;Q5VT25-3;Q5VT25-4;Q5VT25-5;Q5VT25;Q5VT25-2;Q5VT25-6 H0Y7V8 CDC42BPA Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase MRCK alpha 1 S(1)LSLESTDR 85.958 0.024421 0.0 38050.0 45855.0 47339.0 46514.0 49849.0 40297.0 42435.0 44413.0 44112.0 33684.0 True False 44491.11347824381 50407.18135486243 48467.74129415728 43907.97138042267 40081.44629404065 38183.75438118582 38415.24959720507 43247.20580946327 44757.054548294975 39790.64255760273 1.1181300581873355 1.2668099360770742 1.2180688267095257 1.1034748010630768 1.007308344820442 0.9596164305693051 0.9654342611229114 1.0868687467626756 1.1248135659911156 1.0 15.280141576072479 -5.9632584725005335 3.1979405120214506 1.0230435100790247 1.2072448592494058 0.6447184082342827 0.05872508450086213 0.15999555693336429 3.3785579006830786 0.018893759847586206 0.028540502797324646 1.0882822040399552e-06 5.9632584725005335 0.1842013491703811 S(ph)LSLESTDR ddPTM_PC-9_Lapatinib_30min_R1 2 SLSLESTDR 9 0 H0Y7V8;A0A0A0MRJ1;H0Y5V1;A0A0A0MRJ0;Q5VT25-3;Q5VT25-4;Q5VT25-5;Q5VT25;Q5VT25-2;Q5VT25-6 H0Y7V8 CDC42BPA Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase MRCK alpha 1 S(1)LSLESTDR;S(1)LSLESTDR 155.53 7.8345e-05 7048200.0 84078.0 96788.0 76545.0 63052.0 90448.0 93874.0 79232.0 83753.0 94918.0 72209.0 True False 82879.03230198317 96563.89333263713 70251.76557224452 67689.05441530606 85128.02646760995 89859.22785098213 83334.24527484651 87644.4701353586 84227.33530914885 84690.22943755548 0.9786138596199252 1.1402011067148714 0.8295144084364909 0.7992545877469269 1.0051693924194323 1.0610341765249072 0.983988894920768 1.0348828987407734 0.9945342676306252 1.0 16.36990791752409 -6.493027953594989 24.980134490219967 1.0171331514841773 0.9385557115725489 0.15304157026978593 0.08815071139680922 1457.6835737982135 1219839.1625270257 0.02977554218508383 0.03371193506982368 3.213453696329744e-07 6.493027953594989 -0.07857743991162836 S(ph)LSMVDLQDAR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSMVDLQDAR 11 0 A0A3B3ITG3;Q5VWQ8-2;Q5VWQ8;H0Y3A3;Q5VWQ8-3;Q5VWQ8-4;Q5VWQ8-5 A0A3B3ITG3 DAB2IP Disabled homolog 2-interacting protein 1 S(0.852)LS(0.148)MVDLQDAR 184.96 0.0011801 5136300.0 19035.0 18731.0 16682.0 13162.0 16751.0 17561.0 15475.0 15991.0 17636.0 12221.0 True False 18763.55740940851 18687.629520329214 15310.470354382203 14129.977387144874 15765.739113733118 16809.95696669042 16276.219780243466 16734.000238015586 15649.647964686877 14333.383566541088 1.309080812796284 1.3037835367744146 1.068168606756744 0.9858089209395727 1.0999314321383002 1.172783585163414 1.1355462375427954 1.167484297083791 1.091832078032042 1.0 13.807091594764382 -5.2560310180988035 24.651872940313577 1.0973649964676155 1.3064322117786773 0.6807602138845896 0.05906847698620503 223.07551313299294 1016791.2832495945 0.016393139942334194 0.04079927695814081 5.545861019991151e-06 5.2560310180988035 0.20906721531106176 S(ph)LSPGGAALGYR ddPTM_PC-9_AZD4547_30min_R2 5 SLSPGGAALGYR 12 0 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 S(0.913)LS(0.087)PGGAALGYR;S(0.995)LS(0.005)PGGAALGYR;S(0.996)LS(0.004)PGGAALGYR;S(0.973)LS(0.025)PGGAALGY(0.001)R;S(0.998)LS(0.002)PGGAALGYR 202.0 1.9647e-06 892494000.0 250786.0 250791.0 367009.0 480236.0 421056.0 337202.0 284961.0 358912.0 293127.0 346271.0 True False 330530.7313271473 331854.2862646958 362142.220860579 369525.00977223786 362599.64235560386 316116.70563410403 310321.9769573961 303450.39737727 308621.09478936903 334148.1576866891 0.9891741843361181 0.9931351666342445 1.0837773979293888 1.1058717556022546 1.0851463161307986 0.9460375535887524 0.9286957591080498 0.9081312896592337 0.9236055554696331 1.0 18.35012839440092 -6.817293769734137 6.986741789464155 0.9338995079239448 1.0528971674209027 0.6294757024916398 0.0420762498087016 0.14728500836791714 14.710100948351544 0.01630295731011485 0.014459360488893408 1.5230221876738195e-07 6.817293769734137 0.11899765949695784 S(ph)LSPGGAALGYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SLSPGGAALGYR 12 0 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 S(0.703)LS(0.293)PGGAALGY(0.005)R;S(0.99)LS(0.01)PGGAALGYR;S(0.956)LS(0.044)PGGAALGYR;S(0.999)LS(0.001)PGGAALGYR;S(0.999)LS(0.001)PGGAALGYR;S(0.92)LS(0.08)PGGAALGYR 202.0 1.9647e-06 739225000.0 262006.0 287492.0 347001.0 344939.0 430621.0 336486.0 329477.0 301243.0 307819.0 259275.0 True False 306358.44094561675 316032.30579156266 355274.819848621 325613.1861373273 346243.9062887127 318840.0818102514 298266.5533530896 293335.690443342 312320.2705386654 306279.5050802288 1.0002577249345082 1.0318428120379102 1.159969289344248 1.0631243055327326 1.1304834327651645 1.0410101770496607 0.9738377802163413 0.9577385544178146 1.019723048255724 1.0 18.224489305597075 -7.071423413750658 4.352830720041634 0.9852988837340414 1.079169873010956 0.46404408924943397 0.04505103470479011 0.20417802030166246 7.361412223797948 0.018246988653282527 0.01424483746846825 8.483529732176058e-08 7.071423413750658 0.09387098927691462 S(ph)LSPGGAALGYR ddPTM_PC-9_Lapatinib_30min_R1 4 SLSPGGAALGYR 12 0 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 S(0.904)LS(0.096)PGGAALGYR;S(0.999)LS(0.001)PGGAALGYR;S(0.952)LS(0.048)PGGAALGYR;S(0.952)LS(0.048)PGGAALGYR 230.81 6.002999999999999e-16 787007000.0 615820.0 476754.0 585161.0 444645.0 490369.0 511217.0 497167.0 468615.0 530372.0 423025.0 True False 607038.2938724444 475650.1054046779 537051.3213667813 477345.6765922366 461526.4595225476 489353.4406150325 522907.8746031862 490388.56366316596 470635.92029524327 496144.307604618 1.2235115561503103 0.9586930619059483 1.08244982988853 0.9621105579077566 0.9302262516137589 0.9863127181235399 1.053943110075741 0.9883990527489054 0.9485867580895383 1.0 18.92040027566481 -4.7564511261668745 24.996399605840026 0.9917376670787733 1.2235119129403416 0.7120460009587752 0.04452239369448696 87.08663065478748 436345.8737805743 0.011338093402895688 0.09192810419468125 1.7520595931725928e-05 4.7564511261668745 0.23177424586156825 S(ph)LSPIIGK ddPTM_PC-9_AZD4547_30min_R2 1 SLSPIIGK 8 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 S(0.835)LS(0.165)PIIGK 101.46 0.0045792 223510000.0 293970.0 426260.0 451320.0 531890.0 451790.0 492950.0 474920.0 598910.0 531010.0 470890.0 True False 387446.34504414693 564040.2090313804 445335.20191275014 409270.9781185825 389066.7569630602 462125.7585729953 517186.9599580513 506362.2210826619 559078.1045215998 454404.2844277621 0.852646769235602 1.2412739676116487 0.9800418199700014 0.9006758786044092 0.8562127829692838 1.016992520558993 1.1381647965959483 1.1143429726247656 1.230353946212578 1.0 18.79361691203809 -7.169457955686038 4.300335369893267 1.1303307456461453 0.9754292915589335 0.28104248081037553 0.11546684007295648 0.3193219594824559 10.427378647822662 0.04715415969695812 0.03575928721192155 6.76927323495169e-08 7.169457955686038 -0.1549014540872118 S(ph)LSPIIGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSPIIGK 8 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 S(0.657)LS(0.343)PIIGK;S(0.72)LS(0.28)PIIGK 125.16 0.0034119999999999997 340490000.0 459260.0 556100.0 640040.0 660690.0 794700.0 570400.0 679010.0 536430.0 524840.0 472190.0 True False 537003.6472015309 611305.9328631343 655300.9809652155 623673.6812858797 638984.2398016832 540487.219868188 614689.2571933123 522349.28089456644 532514.7921002707 557794.3091460157 0.9627270095739855 1.0959343307016614 1.1748075773101427 1.1181069276965652 1.1455553226779411 0.9689722734813755 1.1019998718423694 0.9364550199414625 0.9546794998958524 1.0 19.089373689891772 -7.392190729522965 1.2384878314826084 0.9631677695639922 1.0985826656237632 0.33715070142669157 0.06939673477480651 0.5207389929097014 1.526093160349547 0.04945310419425878 0.02540172487936153 4.0533048697677406e-08 7.392190729522965 0.13541489605977097 S(ph)LSPIIGK ddPTM_PC-9_Lapatinib_30min_R1 2 SLSPIIGK 8 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 S(0.984)LS(0.016)PIIGK;S(0.853)LS(0.147)PIIGK 119.62 0.0034516 283520000.0 444410.0 612730.0 576910.0 448870.0 497980.0 469630.0 495360.0 434920.0 496440.0 385530.0 True False 438072.63190518663 611311.2613310202 529478.6867369998 481881.3971864249 468689.79546634865 449545.019661 521007.31698490534 455127.9709535212 440525.69945504423 452168.3468135661 0.9688264005923632 1.3519550088787404 1.1709768949291568 1.0657123626238918 1.0365382689195501 0.9941983396868607 1.1522419042740342 1.0065454031906735 0.9742515206104813 1.0 18.7865004769344 -5.813652701001246 3.7975123820874748 1.0339315081529337 1.1844145543354803 0.27302851252355576 0.09782111611108373 0.26159922928361434 7.702119521803205 0.027112462980021835 0.04376765385724255 1.5358446845666389e-06 5.813652701001246 0.1504830461825466 S(ph)LSPILPGR ddPTM_PC-9_AZD4547_30min_R2 2 SLSPILPGR 9 0 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 S(0.954)LS(0.046)PILPGR;S(0.97)LS(0.03)PILPGR 87.258 0.011029 29880000.0 29930.0 25745.0 49840.0 68846.0 49005.0 49353.0 37412.0 46283.0 34857.0 38307.0 True False 39447.11741732606 34066.567779085315 49179.0890351225 52974.61836009687 42201.501637873305 46266.94910813083 40741.5955233526 39131.02582753483 36699.46985802412 36965.883589743346 1.0671222648190983 0.9215677936219416 1.3303912759376828 1.4330678240515629 1.141633786067071 1.2516121519402335 1.1021404486231967 1.0585713643915773 0.9927929835337914 1.0 15.173906777813297 -7.673155498421227 2.0774043757174376 1.0051691806467158 1.1935710826650752 0.2601806904047439 0.1321165558213893 0.5185285159914954 4.440639674568437 0.09614134571927442 0.04339361245598797 2.1224843739132172e-08 7.673155498421227 0.18840190201835938 S(ph)LSPILPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLSPILPGR 9 0 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 S(0.991)LS(0.009)PILPGR;S(0.981)LS(0.019)PILPGR;S(0.595)LS(0.405)PILPGR 87.258 0.011029 37616000.0 43663.0 53132.0 61072.0 64397.0 60382.0 55221.0 56309.0 58012.0 53569.0 46574.0 True False 51054.28351644045 58406.59382284485 62528.1880968498 60789.04486789089 48550.58055581382 52325.11354898533 50975.00387814349 56489.24646879478 54352.345282408714 55017.49752041886 0.9279644807089322 1.0616003354417962 1.13651458017776 1.1049038507309425 0.8824570862714186 0.95106313277091 0.9265234911716029 1.0267505614523762 0.9879101691645774 1.0 15.747602899483685 -6.247980656695891 24.983914993760916 0.9614225226981885 1.063647475818686 0.35436150833031077 0.06280457483982206 887.4857278773809 1647471.1504985136 0.019606475577202718 0.025163243000945763 5.649621374416339e-07 6.247980656695891 0.10222495312049751 S(ph)LSPILPGR ddPTM_PC-9_Lapatinib_30min_R1 3 SLSPILPGR 9 0 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 S(0.644)LS(0.356)PILPGR;S(0.807)LS(0.193)PILPGR;S(0.937)LS(0.063)PILPGR 85.53299999999999 0.012362 73413000.0 89236.0 79986.0 94914.0 82349.0 89498.0 74490.0 74209.0 92730.0 75229.0 58879.0 True False 87963.47827612165 79800.7973313253 87110.53729863542 88405.22016821077 84233.90359983801 71304.23634467115 78051.17891257427 97038.57432750813 66755.91782351036 69056.15669866397 1.2737963200002915 1.1555927978955889 1.261444908942069 1.2801931702335985 1.2197884682086237 1.032554369566453 1.130256629443792 1.4052124961275978 0.9666903143018657 1.0 16.0754824231808 -6.549625020907677 24.18684814705533 1.1328862239941173 1.2393813389329056 0.22263131956249882 0.11826755278949744 290.0369275677143 262279.6708495682 0.038524820606143484 0.03852593660192525 2.820817433878571e-07 6.549625020907677 0.10649511493878827 S(ph)LSPLIK ddPTM_PC-9_AZD4547_30min_R2 1 SLSPLIK 7 0 Q5VY60;Q7Z4H7-3;Q7Z4H7 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 S(0.5)LS(0.5)PLIK 78.516 0.028217000000000002 8674600.0 24057.0 22507.0 25305.0 36273.0 32005.0 27022.0 25027.0 30959.0 27532.0 30359.0 True False 31706.625583314846 29781.94760162645 24969.439166006727 27910.820262263507 27561.658196513297 25332.310068281768 27254.354516276744 26174.997917046236 28987.285312308006 29296.14065056041 1.0822799481169314 1.0165826262530846 0.8523115540657088 0.9527132121319057 0.9407948482110413 0.8646978580025756 0.9303052863297675 0.893462324244594 0.9894574735308524 1.0 14.838423002182472 -5.040684990757116 5.141413481583793 0.9234186786113686 1.0696283660619719 0.5460137903059393 0.045912896854262884 0.11397116317235093 7.5429629688629 0.011082676102874653 0.03442475149411674 9.105735045257091e-06 5.040684990757116 0.14620968745060325 S(ph)LSPNHNTLQTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSPNHNTLQTLK 13 0 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 S(0.495)LS(0.495)PNHNT(0.01)LQTLK 64.565 0.023666999999999997 9107300.0 29723.0 28763.0 87468.0 94861.0 109980.0 100670.0 97903.0 70910.0 92304.0 65088.0 True False 34754.51684399053 31618.400551955245 89553.56884423703 89546.24571351132 88430.20849803578 95390.68798059352 88628.91908366128 69048.68763535534 93653.77137798815 76887.9391636754 0.45201519538723445 0.4112270519391538 1.164728432291567 1.1646331880854488 1.1501180739126033 1.2406456593605708 1.1527024920643567 0.8980431571766772 1.2180554245136215 1.0 16.230469690696296 -5.260603983909513 24.998141366826243 1.127604363846512 0.43162105565774567 0.8900212901008336 0.09729281729180314 20.243395583583364 605732.5648928391 0.025415043097203834 0.059697771790850944 5.4877714517611075e-06 5.260603983909513 -0.6959833081887664 S(ph)LSPPQSQSK ddPTM_PC-9_AZD4547_30min_R2 1 SLSPPQSQSK 10 0 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L0Y9;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 S(0.801)LS(0.199)PPQSQSK 142.97 0.00012790000000000002 152900000.0 398290.0 301880.0 541040.0 732920.0 571760.0 521530.0 519460.0 560750.0 493650.0 574930.0 True False 524937.9350533517 399456.80641484854 533865.456090744 563956.6175011212 492380.9932959981 488918.64665498433 565690.9336726378 474098.9722530977 519743.33119355125 554801.8756950712 0.9461718823421331 0.7199990193154953 0.9622632501411473 1.0165009207919147 0.8874897776420267 0.8812490874196369 1.0196269307199521 0.8545374358353302 0.9368088933412534 1.0 19.081613139624288 S(ph)LSPPQSQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSPPQSQSK 10 0 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L0Y9;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 S(0.981)LS(0.019)PPQSQSK 80.245 0.01792 92876000.0 33743.0 30801.0 30362.0 39578.0 47352.0 38419.0 41197.0 38093.0 41431.0 32440.0 True False 39455.02344537137 33858.71972328249 31085.945228526205 37360.572973607246 38073.71551917617 36404.24000721584 37294.521919548875 37093.09911286977 42036.84999524865 38321.11520510128 1.0295896461833434 0.8835525673526129 0.8111962572630993 0.9749343873122416 0.993544037416422 0.9499786165505364 0.973210766960776 0.9679545836372727 1.0969631173377943 1.0 15.225851925943433 -7.214558496453425 0.7111771906994719 1.0313552439044353 0.9174238659036013 0.2699518159776162 0.06291517665914005 0.9709225464117717 0.9823622695531735 0.05511149843887392 0.037055844193742075 6.101568672130826e-08 7.214558496453425 -0.11393137800083408 S(ph)LSPPQSQSK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSPPQSQSK 10 0 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L0Y9;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 S(0.988)LS(0.012)PPQSQSK 124.21 0.00042043 134050000.0 313070.0 177060.0 228150.0 185570.0 194560.0 182240.0 165110.0 149490.0 220530.0 157160.0 True False 308605.56438999384 176650.02844853405 209392.3876844682 199217.4368433728 183116.36331967718 174446.02002218913 173658.5879105653 156435.85114007586 195691.58911614877 184324.8965974636 1.6742478638897031 0.9583622815441462 1.1359962302962687 1.0807950554744221 0.9934434615177045 0.9464050882022281 0.9421331090710342 0.8486962641932576 1.0616666154627403 1.0 17.491891422084045 -4.759546541138366 24.998767291278224 0.9953113258794392 1.674248719444862 0.8740142558945265 0.07720699924529739 17.403746798566832 229789.7343570728 0.020893723486223138 0.1316376059809071 1.7396162621913505e-05 4.759546541138366 0.6789373935654229 S(ph)LSPQEDALTGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSPQEDALTGSR 13 0 Q96EN8 Q96EN8 MOCOS Molybdenum cofactor sulfurase 1 S(0.939)LS(0.061)PQEDALTGSR 184.0 5.432e-05 12120000.0 39995.0 38395.0 60330.0 44614.0 42157.0 41310.0 45449.0 39888.0 39715.0 30830.0 True False 46765.363562742714 42206.60185628488 61768.496002799075 42114.422220539556 33896.63847655665 39143.630877901225 41143.74169773473 38840.98226482947 40295.75674160171 36419.2349498543 1.2840841831832552 1.1589096232910772 1.696040460153768 1.1563785532158204 0.9307345012389465 1.0748065117731922 1.1297255901829244 1.0664963807809165 1.106441604198578 1.0 15.152412995833336 -5.986554302949182 24.999353166529307 1.0583070294798989 1.3690360198581548 0.5364758258520193 0.13628394153315712 183.92360625285863 341963.08383581927 0.03795838710293489 0.056270067577755885 1.0314441025336137e-06 5.986554302949182 0.31072899037825596 S(ph)LSPQEDALTGSR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSPQEDALTGSR 13 0 Q96EN8 Q96EN8 MOCOS Molybdenum cofactor sulfurase 1 S(0.851)LS(0.149)PQEDALTGSR 184.0 5.432e-05 30508000.0 70391.0 75209.0 90376.0 66676.0 81365.0 80827.0 67829.0 70029.0 88187.0 55918.0 True False 69387.21143187152 75034.85818132725 82945.63414144868 71579.57546461583 76579.27066974468 77370.21762693969 71340.8537301541 73282.80299343348 78254.45140972102 65583.35179394855 1.0580003847603585 1.1441144151502607 1.2647361239182986 1.0914290518347762 1.1676632647618164 1.1797234436877124 1.087789077238605 1.11739947698427 1.1932060388676513 1.0 16.001042015542968 -11.158978497559618 2.8423072167966854 0.9865229935772735 1.1460305497222945 0.3649056067898122 0.05732873521958035 15146933.407679169 14609160.660912812 1501568.1962376588 0.014332229607673979 6.9346013920935726e-12 11.158978497559618 0.159507556145021 S(ph)LSPQLLQQMPSKPEGAAK ddPTM_PC-9_AZD4547_30min_R2 2 SLSPQLLQQMPSKPEGAAK 19 1 Q9UPX8;Q9UPX8-3;A0A2R8Y2H5;A0A087X158 Q9UPX8 SHANK2 SH3 and multiple ankyrin repeat domains protein 2 1 S(0.5)LS(0.5)PQLLQQMPSKPEGAAK;S(0.5)LS(0.5)PQLLQQMPSKPEGAAK 92.551 0.00041116 18936000.0 45535.0 48439.0 55213.0 93438.0 90241.0 77503.0 76276.0 80277.0 60141.0 73226.0 True False 60014.18281316211 64095.95947372745 54480.839544466704 71897.31270270933 77712.59482304491 72656.72515809495 83064.41623380854 67872.03423194286 63319.93047971511 70662.38002825966 0.8493088230138996 0.9070733174865305 0.7710020455393443 1.0174765224997486 1.0997732427348992 1.0282235770863888 1.175511158845612 0.9605115792137079 0.8960911089379084 1.0 16.10865472200107 -5.831954891855642 7.711516575260769 1.0340212360031236 0.8493577863602174 0.5389559992366728 0.0772083533705384 0.18408772065014947 17.315859399626138 0.02268901214470774 0.03387980827111012 1.47246543261444e-06 5.831954891855642 -0.18466344964290615 S(ph)LSPQLLQQMPSKPEGAAK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSPQLLQQMPSKPEGAAK 19 1 Q9UPX8;Q9UPX8-3;A0A2R8Y2H5;A0A087X158 Q9UPX8 SHANK2 SH3 and multiple ankyrin repeat domains protein 2 1 S(0.5)LS(0.5)PQLLQQMPSKPEGAAK 66.041 0.0047902000000000005 7758200.0 35791.0 29949.0 29586.0 26291.0 27255.0 24344.0 22808.0 26974.0 24376.0 20695.0 True False 35280.613776734455 29879.654930561075 27153.553285262675 28224.52784420496 25651.914485391673 23302.8638686357 23988.886639598895 28227.310513428325 21630.51818934039 24272.10317564585 1.4535458061225748 1.2310286716538734 1.1187144801076825 1.1628381619819783 1.0568476204868105 0.960067765862883 0.9883316029930554 1.1629528067329185 0.8911678577175802 1.0 14.567011502855646 -1.522878745286004 0.4876433193895085 1.004121140624496 14.049347490548012 0.7896034705619396 0.07074599099333727 45.39607909655292 0.4987366678274965 0.039832809623089376 602.7751474223127 0.02999999999960858 1.522878745286004 13.045226349923515 S(ph)LSPSHLTEDR ddPTM_PC-9_AZD4547_30min_R2 1 SLSPSHLTEDR 11 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 S(0.497)LS(0.497)PS(0.005)HLTEDR 98.0 0.0029230000000000003 5994000.0 11719.0 12309.0 25318.0 32287.0 37301.0 26615.0 18838.0 29500.0 15849.0 23541.0 True False 15445.398229657349 16287.643534385752 24982.26677751267 24843.730979177402 32122.400012127568 24950.759842621563 20514.545505958413 24941.45284256157 16686.745783625214 22716.836755322744 0.6799097249329119 0.7169855429176081 1.0997247128458199 1.0936263374501871 1.4140349009903865 1.0983377708507498 0.9030546694029346 1.097928074722709 0.73455410906694 1.0 14.471474337845953 -5.250784930053471 11.070797868775074 1.0689712956346538 0.6982040859314103 0.4306580067630109 0.1634412619972423 0.4390471218623087 441.120684449077 0.043982909987196665 0.10884459860979151 5.613258852524323e-06 5.250784930053471 -0.3707672097032435 S(ph)LSPSHLTEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSPSHLTEDR 11 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 S(0.954)LS(0.019)PS(0.014)HLT(0.012)EDR 120.55 0.00085531 65334000.0 17530.0 16378.0 26522.0 20867.0 35230.0 29007.0 28332.0 22317.0 22454.0 17080.0 True False 20497.482766717836 18003.899601568806 27154.385065245107 19697.88964172678 28326.934400671093 27485.8218560949 25648.187854083044 21731.202396816076 22782.347271205464 20176.468794794386 1.0159103148914874 0.8923216339131597 1.3458442773817316 0.9762803314130428 1.403958972641415 1.3622711751813754 1.2711930970150924 1.0770567742965418 1.1291543382994456 1.0 14.30038608134665 -5.250416842663323 24.924403323156856 1.2067156173506164 0.9541159524532633 0.3027059721940639 0.14591526567378243 817.142084741513 1847730.789526298 0.037277759630100264 0.09660043826746971 5.618018401007063e-06 5.250416842663323 -0.2525996648973531 S(ph)LSPSHLTEDR ddPTM_PC-9_Lapatinib_30min_R1 2 SLSPSHLTEDR 11 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 S(0.503)LS(0.448)PS(0.049)HLTEDR;S(0.498)LS(0.498)PS(0.004)HLTEDR 96.866 0.0031892 11146800.0 58419.0 47862.0 81332.0 45993.0 74672.0 72116.0 51970.0 56545.0 85391.0 49666.0 True False 57585.93434726745 47751.178479632516 74645.19691059896 49375.47864815027 70279.93977080043 69031.76679060677 54660.75230883703 59172.28712767132 75773.36637290641 58250.70192421485 0.988587818601529 0.8197528424937712 1.2814471662112092 0.8476374879119671 1.2065080325081028 1.1850804283941208 0.9383707063298841 1.0158210145631459 1.3008146489202628 1.0 15.829987813977011 -5.23858255380988 24.93549659413481 1.0900163102849891 0.904170332708838 0.21691590374973901 0.14604576216939083 1182.1801640377794 1289686.7691423306 0.0355320913843494 0.09386121259186439 5.773211209438986e-06 5.23858255380988 -0.18584597757615118 S(ph)LSPSLLGYQQPALMAAPLSLADAHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSPSLLGYQQPALMAAPLSLADAHR 26 0 Q13469-3;Q13469-4;Q13469-2;Q13469;Q13469-5 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 S(0.515)LS(0.444)PS(0.04)LLGY(0.001)QQPALMAAPLSLADAHR 75.766 5.1618e-05 8605700.0 1083.7 1092.1 1919.0 1635.6 5538.1 5352.0 3713.0 1485.5 1965.5 3801.0 True False 1267.14900594935 1200.5164705625402 1964.756237848028 1543.9626346867453 4452.9490605834935 5071.3316983424675 3361.2777602079022 1446.5071990173533 1994.2417191393204 4490.091211300555 0.28221008133648146 0.26737017447242695 0.43757601914704447 0.3438599712186106 0.991727974116966 1.129449594604907 0.7485989932116118 0.3221554153235948 0.44414280808377793 1.0 12.132529036700763 -6.23568522220811 22.473526340069526 0.7554213649036 0.335570746492753 0.4532124340833906 0.23626032395432367 242.40062444083966 211521.76536110087 0.07926227685714958 0.10226106509564253 5.81185509696789e-07 6.23568522220811 -0.41985061841084703 S(ph)LSPSSNSAFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSPSSNSAFSR 12 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 S(0.98)LS(0.018)PS(0.001)S(0.001)NSAFSR 92.906 0.0056064999999999995 52586000.0 21096.0 22808.0 21749.0 24805.0 25554.0 33901.0 32381.0 29113.0 22377.0 16803.0 True False 24667.13613500739 25072.227507179203 22267.578643541805 23415.256268895035 20546.87714092388 32123.171880700294 29313.637261861593 28348.814597773286 22704.22129187514 19849.250887525188 1.2427237821105952 1.263132178098295 1.1218347115324379 1.179654406182704 1.035146225787147 1.6183568872560825 1.4768132776378258 1.428205767482635 1.143832652452604 1.0 14.276796940507312 -6.738931383413134 24.999931223010275 1.3691655036089478 1.171783115424054 0.17086161656007315 0.17286761328504038 352.8487467875153 391913.0726350162 0.05641159214113057 0.0563710701354445 1.8241838924536577e-07 6.738931383413134 -0.19738238818489395 S(ph)LSPSSNSAFSR ddPTM_PC-9_Lapatinib_30min_R1 2 SLSPSSNSAFSR 12 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 S(0.605)LS(0.391)PS(0.002)S(0.002)NSAFSR;S(0.397)LS(0.397)PS(0.076)S(0.102)NS(0.027)AFSR 141.37 7.823199999999999e-05 105924000.0 143001.0 120842.0 109558.0 107048.0 116063.0 108989.0 92255.0 84177.0 122562.0 64624.0 True False 140961.77951682848 120562.19777351063 100550.56414611006 114920.66702165978 109236.4025286374 104327.79453576793 97031.51249281819 88088.17072324656 108757.77692492372 75794.17229393277 1.8597970694920074 1.5906526072475031 1.3266265875451615 1.516220357628459 1.4412242949895189 1.3764619545046373 1.2801975344031225 1.1622024234480346 1.4349094875415591 1.0 16.20979930544108 -1.5228787452803376 0.16717320074853473 1.041861081118891 3.8419320389709695 0.7254369705171249 0.11728563244704457 34.06213517052156 0.36426531526736844 0.3208199364434705 23.742435362095236 0.029999999999999995 1.5228787452803376 2.8000709578520784 S(ph)LSPVAAPPLREPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSPVAAPPLREPR 14 1 Q8NDT2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 S(0.877)LS(0.123)PVAAPPLREPR 62.732 0.022251 21237000.0 56193.0 54670.0 58024.0 62611.0 70685.0 65703.0 53426.0 55111.0 60136.0 47164.0 True False 65705.36503765968 60097.27629855694 59407.512217245385 59103.10865760078 56834.78166651821 62257.419016478845 48365.10250925598 53664.39464493122 61015.375233865285 55714.45984998145 1.1793233787885598 1.0786656903858856 1.066285348134182 1.0608217115761998 1.0201082774481414 1.1174373615775002 0.8680888702768619 0.9632040728642025 1.0951443377205352 1.0 15.765764185508413 -1.5228787453345267 0.3752899580583173 0.9931633387443191 3.42500621978159 0.3826477737261006 0.06492224854978067 71.99677860572899 0.9885988901825524 0.05176865278646881 126.80783970724214 0.029999999996256747 1.5228787453345267 2.431842881037271 S(ph)LSPVAAPPLREPR ddPTM_PC-9_Lapatinib_30min_R1 2 SLSPVAAPPLREPR 14 1 Q8NDT2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 S(0.653)LS(0.347)PVAAPPLREPR;S(0.879)LS(0.121)PVAAPPLREPR 61.961999999999996 0.023622 68784000.0 156375.0 135815.0 172222.0 164023.0 174464.0 172809.0 158331.0 170651.0 178961.0 157104.0 True False 154145.0638243372 135500.52871194843 158062.57195614546 176085.79858468822 164202.37052942105 165418.36190745435 166528.6044604672 178580.0684521046 158804.52763712435 184259.21707207826 0.8365663670655833 0.7353799221829078 0.8578272200859008 0.9556417387565868 0.8911487476102137 0.8977480993135135 0.9037735376641961 0.9691784828448929 0.8618539151558612 1.0 17.49137726250391 -1.8280106459425578 0.2396703738022786 0.9629647530679908 4.867319792098657e-13 0.49454850170532716 0.0510256066849464 36.128992545311554 0.5493069863514866 0.07089297850402661 13.430054912778315 0.014858992177127519 1.8280106459425578 -0.9629647530675041 S(ph)LSQGSTNATVLDVAQTGGHK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSQGSTNATVLDVAQTGGHK 21 0 A0A2R8Y661;H0Y8T6 A0A2R8Y661 RAPGEF2 1 S(0.444)LS(0.375)QGS(0.153)T(0.028)NATVLDVAQTGGHK 99.219 0.00013363 19094000.0 100460.0 95556.0 72127.0 85244.0 96848.0 95745.0 85878.0 98158.0 88764.0 86238.0 True False 99027.42197789245 95334.74595294295 66196.9964782714 91513.12812564807 91151.591050494 91650.20954249617 90324.34263571876 102718.77902339668 78766.46359364173 101144.12339508791 0.9790724231310283 0.9425633714827658 0.6544818844263796 0.9047794874664209 0.901205013112218 0.906134795241571 0.8930261057569795 1.0155684341853246 0.7787547209832959 1.0 16.626052974312692 -5.96959259556425 24.999970034022155 0.913853923391235 0.8525149165283457 0.060459066495410774 0.10000738427957995 590.9327827285086 485841.74501213065 0.028182202309564416 0.04180048025677879 1.0725249513060024e-06 5.96959259556425 -0.06133900686288929 S(ph)LSQPTPPPMPILSQSEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSQPTPPPMPILSQSEAK 19 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y314 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 S(0.969)LS(0.031)QPTPPPMPILSQSEAK 178.02 9.015799999999998e-37 0.0 11289.0 11672.0 11149.0 10875.0 16686.0 11050.0 7732.9 12606.0 7768.5 5517.0 True False 13200.004732086578 12830.71902243931 11414.83444281795 10265.709007225707 13416.498081453234 10470.518547586751 7000.383730652224 12275.105857161057 7882.099615941907 6517.188427452029 2.0254140077467846 1.9687506606979646 1.7514967642696673 1.5751744976382716 2.0586328338980633 1.6066005554607423 1.0741416806616877 1.8834971543028032 1.209432518897341 1.0 12.670033991971891 -1.8793610395252607 0.06108781674297539 9.995200922423395e-11 4.909650287071555 0.5727429305034881 0.24614071891276365 231.2264484659163 1.127944901930275 19.014450131560068 102.0914596215603 0.013201976655596012 1.8793610395252607 4.909650286971603 S(ph)LSQPTPPPMPILSQSEAK ddPTM_PC-9_Lapatinib_30min_R1 2 SLSQPTPPPMPILSQSEAK 19 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y314 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 S(0.954)LS(0.046)QPTPPPMPILSQSEAK;S(0.984)LS(0.013)QPT(0.004)PPPMPILSQSEAK 142.55 0.00021481 5858400.0 21971.0 22324.1 22727.0 22938.2 17617.1 15131.300000000001 12231.0 12425.6 18989.3 19935.4 True False 21657.689511012068 22272.409918038604 20858.473788756997 24625.151747592045 16580.896814551226 14484.169571783088 12864.261333257367 13002.938737882967 16850.525067806106 23381.20732774925 0.9262861924716916 0.9525774099614307 0.8921042226934867 1.0532027453674926 0.7091548602313924 0.6194791128083881 0.5501966238496943 0.5561277720013559 0.7206866964396484 1.0 14.513061807314026 -6.3847106390180635 5.19717811004098 0.6542680884232599 0.9500881409495635 0.4985427791215278 0.12683132230211613 0.16801925540050155 6.4391245870967895 0.03816814595138451 0.04332304207458724 4.123721822158642e-07 6.3847106390180635 0.2958200525263036 S(ph)LSRTPETLLPFAEAEAFLKK ddPTM_PC-9_AZD4547_30min_R2 1 SLSRTPETLLPFAEAEAFLKK 21 2 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.435)LS(0.435)RT(0.121)PET(0.009)LLPFAEAEAFLKK 61.091 0.0028986999999999997 1233500.0 1097.8 1110.4 3780.1 7817.4 5214.4 4745.0 2687.4 3325.2 3229.7 4948.3 True False 1446.8775643414813 1469.3150849445074 3729.9734041265356 6015.219207626022 4490.470567095731 4448.294399896273 2926.5733938163658 2811.3667454944325 3400.415348436769 4775.0615231453 0.303007104165735 0.30770600081748883 0.7811361981509356 1.2597155405159761 0.9404005676848094 0.9315679763150385 0.612887054885243 0.5887603189754516 0.7121196935274121 1.0 12.221303605991588 -5.2862840578343135 4.936677718626886 0.8534690836329009 0.29898056020173935 0.5805056129692945 0.18701868143971628 0.13787643970274593 9.502179438998166 0.0556492196277701 0.12978304749113245 5.172683929225215e-06 5.2862840578343135 -0.5544885234311615 S(ph)LSSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSSLR 6 0 H0Y9X0;A0A286YEZ9;A0A2C9F2R7;O94915;C9J1G1;Q70YC5-2;Q70YC5;Q70YC5-4;Q70YC5-3;Q8TF61 H0Y9X0;Q8TF61 FRYL;ZNF365;FBXO41 Protein furry homolog-like;Protein ZNF365;F-box only protein 41 1 S(1)LSSLR 93.195 0.034816 24157000.0 44322.0 37296.0 47341.0 44741.0 61295.0 41161.0 38278.0 49099.0 44166.0 39132.0 True False 51824.839200597125 40998.50039932288 48469.78898174229 42234.30682227909 49284.68475983913 39002.44470020072 34652.0307312788 47810.203274690706 44811.84419613697 46226.321831258414 1.1211110282530194 0.8869081245308932 1.0485322444358278 0.913641950065776 1.0661606376502282 0.8437280569839135 0.7496168710495795 1.0342636268837047 0.9694010343222902 1.0 15.496426953308418 -6.7619529595953916 24.999999679970145 0.9109318361455022 0.9976746763746254 0.1573992515022199 0.09947134623301568 27.826201007617716 1354468.1074991208 0.03420959818731865 0.03201011055283831 1.730003733616184e-07 6.7619529595953916 0.08674284022912315 S(ph)LSSPTVTLSAPLEGAK ddPTM_PC-9_AZD4547_30min_R2 1 SLSSPTVTLSAPLEGAK 17 0 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 S(0.435)LS(0.435)S(0.129)PT(0.001)VTLSAPLEGAK 173.19 7.123200000000001e-06 29404000.0 41403.0 29011.0 48960.0 59144.0 49621.0 46262.0 43244.0 52382.0 42584.0 55671.0 True False 54568.292764101294 38388.23840897431 48310.75841010432 45509.26456569111 42731.98067080725 43369.2298267653 47092.63222527157 44287.5655186122 44834.90330304095 53721.975234933605 1.0157536562173417 0.7145723559325071 0.8992736808137585 0.8471256756043095 0.7954283230267392 0.807290306008029 0.8765990457225185 0.8243845339814214 0.8345728746378318 1.0 15.713224729907784 -10.97839265014448 4.319635419916504 1.0007049439528624 0.8414610375562984 0.27849548546274905 0.07396852531364896 0.00045994473755590524 5.79755118626195e-05 0.06559759673291742 0.01584010640183063 1.0510112140003011e-11 10.97839265014448 -0.15924390639656394 S(ph)LSSPTVTLSAPLEGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSSPTVTLSAPLEGAK 17 0 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 S(0.878)LS(0.061)S(0.061)PTVTLSAPLEGAK 293.52 7.074799999999998e-112 132970000.0 35236.0 33096.0 33760.0 37712.0 41200.0 33360.0 35226.0 42671.0 35767.0 26783.0 True False 41200.7588572772 36381.55215615589 34564.96643551297 35599.11890395363 33127.15575667468 31610.542873076374 31889.138265845293 41550.931463661705 36290.02471048391 31638.545885888656 1.3022330105143505 1.1499122711699181 1.0924954187268623 1.125181891492411 1.047050514778872 0.9991149083490347 1.0079204771565815 1.3133009213989872 1.1470193618054327 1.0 14.94939567432143 -4.705076988109313 2.0429212634161296 1.0955680202381044 1.3907576395931482 0.3368651029004056 0.08915121758256815 1.212117453755183 4.732595817974257 0.0255518060555259 0.7204207081432542 1.9720731124269766e-05 4.705076988109313 0.29518961935504384 S(ph)LSSS(ph)PVKK ddPTM_PC-9_AZD4547_30min_R2 1 SLSSSPVKK 9 1 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 2 S(0.993)LS(0.053)S(0.283)S(0.672)PVKK 118.77 0.001838 0.0 46550.0 39839.0 45635.0 53024.0 56729.0 56578.0 53215.0 57784.0 49218.0 56035.0 True False 61351.931699850575 52716.17765589354 45029.8500826207 40800.13601263366 48853.157563818226 53040.16871598128 57951.031908885125 48854.81054422297 51819.562999461574 54073.231705726605 1.1346081927141989 0.9749034040129444 0.8327567756201232 0.7545348174245102 0.9034628784475711 0.9808951128468262 1.0717138606448011 0.9034934477394851 0.9583219157580634 1.0 15.72262696172299 -6.765153512654431 22.6701966602992 0.9824050613783278 0.909055170485367 0.08475549142484817 0.10001718836800917 77.1757338489092 471053.2148535129 0.037771108069481286 0.034668252919830105 1.7173012551685775e-07 6.765153512654431 -0.07334989089296085 S(ph)LSSS(ph)PVKK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSSSPVKK 9 1 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 2 S(1)LSS(0.042)S(0.958)PVKK 107.11 0.014569 8939900.0 85017.0 66872.0 67153.0 66554.0 67008.0 62841.0 52825.0 58082.0 64991.0 45260.0 True False 83804.64198979146 66717.16199260353 61631.93955807621 71448.60317763544 63066.721182796704 60153.43691952578 55560.02002528994 60780.70175876561 57671.029194429844 53083.13069484083 1.5787433953652712 1.256843014330498 1.1610456796977544 1.34597568459879 1.1880746360901089 1.133193090387416 1.0466605736705321 1.1450097415726255 1.0864285591210414 1.0 15.695965838892247 -1.5228787452803376 0.3454338342534238 1.0675485749424185 6.009437678746332 0.753116944373703 0.07906502790507264 33.04705048953709 0.4667064012413995 0.07072802423444406 105.89654621626543 0.029999999999999995 1.5228787452803376 4.941889103803914 S(ph)LSSSATPLSSPAR ddPTM_PC-9_AZD4547_30min_R2 1 SLSSSATPLSSPAR 14 0 Q9H6K5;Q9H6K5-2 Q9H6K5 PRR36 Proline-rich protein 36 1 S(0.923)LS(0.068)S(0.008)SATPLSSPAR 143.56 0.00016708 6985800.0 26084.0 22401.0 25843.0 30628.0 30131.0 30672.0 25346.0 29217.0 29310.0 26348.0 True False 34378.16941909568 29641.685174569422 25500.30493448378 23567.18779788291 25947.830748918692 28754.07499127893 27601.744898291865 24702.18398986854 30859.266762449068 25425.564539707026 1.3521103677130706 1.1658221050816038 1.0029395766084184 0.9269091256981966 1.0205409877289469 1.1309119585672829 1.0855902473743033 0.9715490860110978 1.213710189768107 1.0 14.633992187047905 -4.89173995468854 2.7819068321389557 1.0432859510823513 1.373711358721632 0.5935654288213283 0.07872614816667822 0.24016216880037247 3.022925145833774 0.02082191973178554 0.16357144650951252 1.2830986419448293e-05 4.89173995468854 0.33042540763928074 S(ph)LSSSATPLSSPAR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSSSATPLSSPAR 14 0 Q9H6K5;Q9H6K5-2 Q9H6K5 PRR36 Proline-rich protein 36 1 S(0.694)LS(0.264)S(0.029)S(0.006)AT(0.001)PLSS(0.005)PAR 86.756 0.0063767 5844300.0 39902.0 36459.0 31267.0 32870.0 39509.0 34886.0 28300.0 36349.0 40292.0 23187.0 True False 39332.99016286938 36374.58142553431 28696.347954110326 35287.3694511056 37185.1582976826 33394.00710323796 29765.235527036533 38037.90723854846 35753.89066643023 27194.842055264562 1.4463400847461452 1.337554428579322 1.0552128927902742 1.2975758189510953 1.367360701051913 1.227953706639503 1.0945176834102766 1.3987177112942573 1.3147305872846113 1.0 14.73104542635844 -10.890904091040587 3.2402597411028533 0.9975309972702744 1.2764348175523401 0.33433533655522985 0.11921448709166349 249358208.42943066 344656681.5386813 5849155.986101792 0.03055646734417131 1.2855705321171764e-11 10.890904091040587 0.27890382028206573 S(ph)LSSSLDDTEVKK ddPTM_PC-9_AZD4547_30min_R2 1 SLSSSLDDTEVKK 13 1 O95292 O95292 VAPB Vesicle-associated membrane protein-associated protein B/C 1 S(0.994)LS(0.006)SSLDDTEVKK 170.95 0.00033831 6507300.0 14841.0 15026.0 28453.0 27956.0 23241.0 22360.0 22605.0 32180.0 30534.0 16702.0 True False 19560.129288023265 19882.860650554907 28075.694629140056 21511.176115894435 20014.388318861606 20961.82566526462 24616.801208312478 27207.320422834957 32147.96490360352 16117.268063693136 1.2136132011159977 1.2336371506623014 1.7419636205211038 1.334666398231099 1.2417978183255132 1.3005818096731088 1.5273556976920903 1.6880851218280617 1.9946286663818809 1.0 13.976319602014597 -7.452169646800763 4.100866510284875 1.6288462265142865 1.3534440699141606 0.10900949425053164 0.27090688593408546 0.4050540766301794 13.071938872755888 0.12039820463215685 0.07604739053888965 3.5304523413676996e-08 7.452169646800763 -0.2754021566001259 S(ph)LSSSLDDTEVKK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSSSLDDTEVKK 13 1 O95292 O95292 VAPB Vesicle-associated membrane protein-associated protein B/C 1 S(0.576)LS(0.342)S(0.041)S(0.041)LDDTEVKK 61.097 0.025118 3636100.0 36180.0 34080.0 16593.0 11351.0 17864.0 19869.0 25869.0 21070.0 22832.0 9844.1 True False 35664.0665654006 34001.089853868965 15228.78759083228 12185.790405825977 16813.2746419753 19019.24918690119 27208.370242010882 22048.98911981668 20260.419728381185 11545.639568561272 3.0889641369468785 2.9449290922309572 1.3190077085292187 1.0554452469664681 1.4562445451491293 1.6473101445753189 2.356592727534918 1.9097243586103265 1.7548113820866384 1.0 13.495060472699132 -5.251744945956974 23.17188565267718 1.6043830512035482 3.0169474330948742 0.6972270757348924 0.3826085449796237 151.90477842462852 363080.522107517 0.10779958436226904 0.27642296244572356 5.600864345250452e-06 5.251744945956974 1.412564381891326 S(ph)LSTSGESLYHVLGLDK ddPTM_PC-9_AZD4547_30min_R2 1 SLSTSGESLYHVLGLDK 17 0 Q9H3Z4-2;Q9H3Z4 Q9H3Z4-2 DNAJC5 DnaJ homolog subfamily C member 5 1 S(0.504)LS(0.404)T(0.018)S(0.021)GES(0.052)LYHVLGLDK 75.703 0.0049862 150350000.0 63639.0 80166.0 256470.0 300770.0 264940.0 223180.0 193270.0 344680.0 204100.0 220880.0 True False 83874.87822656921 106078.09176842704 253069.04022547862 231432.12335017778 228157.654197289 209224.51931904117 210470.65558639955 291417.62595844513 214888.30932159149 213147.05843063933 0.39350708775492266 0.49767560739265915 1.1872978313131655 1.085786147151961 1.0704236590322653 0.9815970291099532 0.9874433976994774 1.3672139231200136 1.008169246640196 1.0 17.701489619737195 -5.2208345614636 6.15501738437701 1.0913917296409121 0.4345694488649199 0.8361810452325189 0.11341958909619917 0.0740969235594377 7.813355637215185 0.029197430873110344 0.0775354182170077 6.014027900115763e-06 5.2208345614636 -0.6568222807759923 S(ph)LSTSGESLYHVLGLDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSTSGESLYHVLGLDK 17 0 Q9H3Z4-2;Q9H3Z4 Q9H3Z4-2 DNAJC5 DnaJ homolog subfamily C member 5 1 S(0.494)LS(0.494)T(0.005)S(0.005)GES(0.002)LYHVLGLDK 99.34299999999999 0.00071807 1474900.0 2803.4 5337.4 5851.7 5793.6 9185.5 6082.3 5237.2 4685.3 6512.0 4004.9 True False 3277.960250326114 5867.261798352259 5991.226720695832 5469.003375104627 7385.667213663472 5763.333480722794 4741.094501955518 4562.3158394857 6607.225680506366 4730.956667229045 0.6928747145439484 1.2401850642586325 1.2663879934045004 1.1560036922316308 1.5611360942752641 1.2182173471689013 1.002142872031929 0.9643537576846759 1.3965939967859113 1.0 12.207916231337059 -10.667520965139452 14.444582914047082 1.0000009025805339 1.173591571123827 0.044979179132466296 0.22793229634199355 0.0 0.0 0.22222574286061034 0.05389765944386155 2.1502008779998466e-11 10.667520965139452 0.17359066854329308 S(ph)LSVEHLETK ddPTM_PC-9_AZD4547_30min_R2 2 SLSVEHLETK 10 0 J3KN34;P26045-2;P26045 J3KN34 PTPN3 Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 3 1 S(0.662)LS(0.338)VEHLETK;S(0.75)LS(0.25)VEHLETK 100.38 0.0022735 6347000.0 56269.0 55056.0 68920.0 88478.0 81184.0 72588.0 56929.0 79759.0 53452.0 68613.0 True False 74161.37153209226 72851.77532124003 68006.07576847194 68080.76407147328 69913.0029378451 68049.06088507277 61995.57071391376 67434.07922948708 56277.36359557921 66210.87975417174 1.1200783286287568 1.1002991591672646 1.027113308582599 1.0282413452931614 1.0559141216280261 1.0277625238892136 0.9363350999728653 1.0184742972734517 0.8499715425097241 1.0 16.014780679327018 -6.135059676850624 0.4637518394327576 0.941508492795714 1.1331932173883783 0.5608595599392017 0.04874878460014329 1.205258694184605 0.46102572886893584 0.041146470974346636 0.11159499894924661 7.327238418856592e-07 6.135059676850624 0.19168472459266428 S(ph)LSVEHLETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSVEHLETK 10 0 J3KN34;P26045-2;P26045 J3KN34 PTPN3 Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 3 1 S(0.5)LS(0.5)VEHLETK 74.392 0.014700999999999999 2938100.0 34198.0 37500.0 34642.0 36616.0 40340.0 33725.0 33740.0 27321.0 27422.0 25996.0 True False 39987.0459587117 41222.75217113384 35467.99666051661 34564.52423067369 32435.66658311301 31956.401630530578 30543.902943553643 26603.852698992327 27822.99487267284 30708.86901577724 1.3021334630776416 1.34237285488941 1.1549756730635141 1.1255551030848951 1.0562312329525583 1.040624505386779 0.994628064220182 0.8663247313121207 0.9060247337138424 1.0 14.906367759483699 -5.762576539182754 0.5681399151786622 0.9198634376929061 1.4141166054429921 0.8944575330869043 0.047922378218803054 0.45504463919204463 0.23348411076977177 0.03265569457042469 0.13104753963532803 1.727521498776538e-06 5.762576539182754 0.494253167750086 S(ph)LSVEHLETK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSVEHLETK 10 0 J3KN34;P26045-2;P26045 J3KN34 PTPN3 Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 3 1 S(0.727)LS(0.273)VEHLETK 85.973 0.006553 3521800.0 54214.0 40062.0 51486.0 41017.0 48697.0 45223.0 41645.0 37746.0 49780.0 39793.0 True False 53440.89841837002 39969.23890040195 47253.01982170738 44033.52700870089 45832.738201985645 43288.9177099619 43801.174329450034 39499.816958547686 44173.25219336091 46671.167029160475 1.14505168437249 0.8564011025357238 1.0124670718472362 0.9434845925577227 0.9820354004293277 0.9275302175948306 0.9385060866826568 0.8463430308881696 0.9464784149443092 1.0 15.510243922406078 -4.747014381728005 24.999793192066036 0.937815758964306 1.145052217680464 0.5888375018165738 0.05157920460855087 535.6908026577568 928347.2833128037 0.012523551434090419 0.26770338231484314 1.7905465588311332e-05 4.747014381728005 0.20723645871615803 S(ph)LSVPVDLSR ddPTM_PC-9_AZD4547_30min_R2 1 SLSVPVDLSR 10 0 Q9NYF3;D6RHW3 Q9NYF3 FAM53C Protein FAM53C 1 S(0.862)LS(0.138)VPVDLSR 141.89 0.00012582 8379900.0 24465.0 23497.0 39181.0 45856.0 29436.0 33456.0 27196.0 34379.0 29417.0 25211.0 True False 32244.36109638765 31091.94574112129 38661.434339589396 35284.607668137636 25349.31950234545 31363.991031175898 29616.391314366974 29066.515500827936 30971.92256400422 24328.37056363117 1.3253810407093274 1.278011844640392 1.58915017503823 1.4503481676197871 1.0419653645131708 1.2891940686756216 1.2173602517647006 1.194758005876476 1.2730783791292866 1.0 14.570352075966735 -6.243137861181331 24.953962193485214 1.1875190228331074 1.4139882824751495 0.5082409400625847 0.11545343536858711 729.5560590776213 994743.2409066856 0.03433741773855571 0.04423958186054005 5.7129725693999e-07 6.243137861181331 0.22646925964204212 S(ph)LSVPVDLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSVPVDLSR 10 0 Q9NYF3;D6RHW3 Q9NYF3 FAM53C Protein FAM53C 1 S(0.999)LS(0.001)VPVDLSR 141.71 0.00012548 52860000.0 58158.0 59083.0 69501.0 74377.0 72917.0 65037.0 72181.0 70568.0 71241.0 55587.0 True False 68003.00072714056 64948.36977405597 71158.1674240103 70209.89782348761 58629.43728906419 61626.34522890493 65343.49313481463 68715.6647729764 72282.76485026925 65664.48307355004 1.0356131281955143 0.9890943586856237 1.083662949791394 1.0692218157698172 0.8928637605110517 0.9385034701313031 0.9951116657938831 1.046466241057723 1.1007893684216798 1.0 16.002825629112955 -11.366479090774051 10.098906372621217 0.999636804843509 1.013791309906316 0.004474098564777762 0.06190128563256893 0.0005640563473651856 8.735382252313646e-06 0.06678694813747472 0.015783399138875588 4.3005193809965255e-12 11.366479090774051 0.014154505062807021 S(ph)LSVPVDLSR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSVPVDLSR 10 0 Q9NYF3;D6RHW3 Q9NYF3 FAM53C Protein FAM53C 1 S(0.985)LS(0.015)VPVDLSR 137.01 0.00011643 62176000.0 84360.0 79411.0 84135.0 70382.0 79840.0 82870.0 67620.0 68726.0 78741.0 73861.0 True False 83157.0109302706 79227.1287084971 77217.74507049195 75558.12706746909 75143.96817147937 79325.84327940516 71121.0327327989 71919.2608565981 69872.35940051083 86627.77543640399 0.9599347381524141 0.9145695859021576 0.8913739811681968 0.8722159455997869 0.867435043701945 0.9157091115382573 0.8209957184576552 0.8302101779053089 0.8065814809224346 1.0 16.402542049531682 -4.097326873050211 0.6694468505074735 0.861761890776775 1.1463153479773405 0.19562247595885873 0.052552275912927174 10.168622890613396 1.7744143591397377 0.02162954207975468 2.7157074295876216 7.992324838361739e-05 4.097326873050211 0.28455345720056546 S(ph)LSVVAT(ph)T(ph)TFLTGIIQIIGFTVIANK ddPTM_PC-9_AZD4547_30min_R2 1 SLSVVATTTFLTGIIQIIGFTVIANK 26 0 Q96RN1-2 Q96RN1-2 3 S(0.885)LS(0.124)VVAT(0.504)T(0.504)T(0.494)FLT(0.473)GIIQIIGFT(0.016)VIANK 42.611999999999995 0.034286000000000004 5346400.0 6141.0 4881.1 37314.0 82114.0 49252.0 24362.0 9502.2 55324.0 14150.0 19470.0 True False 8093.710259264931 6458.820119887099 36819.19197946551 63183.88594865338 42414.20995140361 22838.640288782506 10347.877391799455 46774.94701904669 14897.94011220247 18788.36122620677 0.43078319401138054 0.3437670822976341 1.9596808649872353 3.362926930557516 2.257472561909367 1.215573833918322 0.5507599767331393 2.4895703492118884 0.7929345158332499 1.0 14.197551615869422 S(ph)LSYEEPR ddPTM_PC-9_AZD4547_30min_R2 1 SLSYEEPR 8 0 Q8IZD4;Q8IZD4-2;F5GZK9 Q8IZD4 DCP1B mRNA-decapping enzyme 1B 1 S(0.643)LS(0.357)YEEPR 114.86 0.0036591 39868000.0 44952.0 46541.0 63249.0 96486.0 62964.0 65329.0 62186.0 87564.0 62115.0 66630.0 True False 59245.80094031548 61584.468091140436 62410.276933837566 74242.64339384003 54222.53543775235 61243.96730259719 67720.43352975535 74032.9958205445 65398.27208971421 64297.303980593584 0.9214352278004881 0.9578079371683773 0.9706515370018381 1.1546773938802812 0.8433096270120123 0.9525122129705786 1.0532390837132914 1.1514167972406646 1.0171230835658822 1.0 15.972470625417264 -7.328242188233608 5.640072881354741 1.0695811074819919 0.969525437037881 0.21245759447561885 0.08208252473149016 0.33653308403537785 20.795077326986075 0.035303017615526434 0.02366377644637438 4.696321409698926e-08 7.328242188233608 -0.1000556704441109 S(ph)LSYEEPR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSYEEPR 8 0 Q8IZD4;Q8IZD4-2;F5GZK9 Q8IZD4 DCP1B mRNA-decapping enzyme 1B 1 S(0.996)LS(0.004)YEEPR 134.23 0.0039811 31178000.0 55607.0 51527.0 55108.0 40775.0 60286.0 50421.0 49366.0 57697.0 71313.0 46450.0 True False 54814.0339829251 51407.69239730947 50577.23296303167 43773.729521412555 56740.096006836284 48264.61136709172 51921.929930306906 60377.81325325401 63280.978980818494 54478.82060926549 1.0061530952746545 0.9436271164168025 0.928383404732329 0.8034999479039334 1.0415074220088056 0.8859334843765526 0.9530663356812148 1.108280476302845 1.1615702813150837 1.0 15.73340785089537 -7.729711155286837 5.506507357261893 1.1020516626583365 0.9331713632489116 0.4903468903158028 0.07099687834177905 0.13483409514621586 10.790867155325342 0.034704105480141585 0.018788717297176297 1.8633260032556835e-08 7.729711155286837 -0.16888029940942495 S(ph)LTFTGGAK ddPTM_PC-9_AZD4547_30min_R2 4 SLTFTGGAK 9 0 F5H8C5;F5H0S5;F5H7J1;Q8NHQ8-2;Q8NHQ8 F5H8C5 RASSF8 Ras association domain-containing protein 8 1 S(0.996)LT(0.004)FTGGAK;S(0.98)LT(0.02)FTGGAK;S(0.939)LT(0.06)FTGGAK;S(0.999)LT(0.001)FTGGAK 139.43 0.00083171 56646000.0 216048.0 191072.0 253325.0 301565.0 268035.0 265845.0 257615.0 292232.0 232147.0 299809.0 True False 284746.769922435 252832.28738339024 249965.74498038567 232043.84838280524 230822.96687087783 249221.6701244312 280542.2359336167 247074.25922330338 244417.8164825066 289312.778164758 0.9842177442998292 0.8739063963479939 0.8639982878254864 0.8020518480198645 0.797831911660081 0.861426417821422 0.9696849123402816 0.8540039634288099 0.8448220574043066 1.0 18.142270519058663 -7.046182936800092 24.969686500857776 0.9064748800060224 0.8582616140097522 0.12730316339747405 0.06500048153454435 1027.7989637564888 555696.3027447843 0.025727664013406773 0.019929268619768202 8.991187681574852e-08 7.046182936800092 -0.04821326599627018 S(ph)LTFTGGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLTFTGGAK 9 0 F5H8C5;F5H0S5;F5H7J1;Q8NHQ8-2;Q8NHQ8 F5H8C5 RASSF8 Ras association domain-containing protein 8 1 S(0.996)LT(0.004)FTGGAK 97.81299999999999 0.0046629 18111000.0 52652.0 64393.0 56399.0 64772.0 69187.0 52341.0 60631.0 54720.0 59781.0 42354.0 True False 61564.943675597715 70785.51148148849 57743.76605439861 61143.03483365728 55630.30401303517 49596.14581893554 54887.59274957323 53283.6579806325 60655.18403045927 50032.44492592049 1.2305004036231406 1.4147921730847972 1.154126410170355 1.2220676987540275 1.111884580004096 0.9912796764653227 1.0970399873690246 1.0649820943095196 1.2123170098976197 1.0 15.610576333505408 -5.81694979653477 1.2963889689718688 1.0785744661524859 1.3158931306886923 0.5479400447143852 0.08092501702311815 0.3405660421901029 1.147707251462701 0.027575663059906597 0.06428267257277283 1.5242289410507396e-06 5.81694979653477 0.23731866453620643 S(ph)LTFTGGAK ddPTM_PC-9_Lapatinib_30min_R1 1 SLTFTGGAK 9 0 F5H8C5;F5H0S5;F5H7J1;Q8NHQ8-2;Q8NHQ8 F5H8C5 RASSF8 Ras association domain-containing protein 8 1 S(0.988)LT(0.012)FTGGAK 88.056 0.010413 14081000.0 48768.0 44241.0 50458.0 43481.0 46843.0 56351.0 45360.0 37678.0 47293.0 49582.0 True False 48072.5593770441 44138.562682658936 46309.538013512596 46678.737788363935 44087.78683688138 53940.999090596866 47708.51885181544 39428.65743030151 41966.36432263189 58152.18263613783 0.8266681867787727 0.7590181603128627 0.796350814607846 0.8026996695968572 0.7581450057127118 0.9275833966217463 0.8204080515830487 0.67802540924404 0.7216644744913238 1.0 15.827545721191841 -4.417070056413654 18.898331156838136 0.7988406563369761 3.607663292963919 0.0 0.0901778646640624 1027.5852612709828 183351.2704113082 0.021338343874694517 125.4997481481956 3.827629945111524e-05 4.417070056413654 2.808822636626943 S(ph)LTIAEFK ddPTM_PC-9_AZD4547_30min_R2 1 SLTIAEFK 8 0 K7EK42;A0A494C0X0;Q99426;K7EL99 K7EK42 TBCB Tubulin-folding cofactor B 1 S(0.999)LT(0.001)IAEFK 71.34899999999999 0.035651999999999996 1016400.0 7362.0 7132.2 7152.6 10537.0 10249.0 10137.0 8088.8 10547.0 5730.2 7497.2 True False 9702.96286088722 9437.544172227312 7057.751850574185 8107.857445027178 8826.103260617554 9503.131787512859 8808.687529918068 8917.203495949054 6033.0866735648415 7234.72530997008 1.3411653442482045 1.3044785762939135 0.9755383305082764 1.120686286990585 1.219963838634539 1.313544243955844 1.2175565971770803 1.2325559180056735 0.8339068057291302 1.0 12.820722525818928 -8.253992140762461 24.735885056797706 0.9169533945990814 1.2109411850039469 0.555346600331609 0.10685563822673974 350.70597492029265 1164875.7659512926 0.08040916639952733 0.029031962633017543 5.5719583217028446e-09 8.253992140762461 0.29398779040486545 S(ph)LTIAEFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLTIAEFK 8 0 K7EK42;A0A494C0X0;Q99426;K7EL99 K7EK42 TBCB Tubulin-folding cofactor B 1 S(1)LTIAEFK 90.10799999999999 0.009722399999999999 1658600.0 11836.0 11185.0 11399.0 15236.0 15236.0 13487.0 13392.0 11633.0 12060.0 10127.0 True False 13839.601028344114 12295.372880910189 11670.795390948238 14382.37631577846 12250.615172541136 12779.71797749343 12123.412810316247 11327.646076182342 12236.354684721558 11962.944934712112 1.156872417609031 1.027788136450707 0.975578793904153 1.2022437948406866 1.0240467743853197 1.068275248882183 1.0134137435622994 0.9468944426312317 1.0228547194274975 1.0 13.54628496304156 -7.3280873885385125 2.846665715060317 0.9871388868695514 1.0736585550103386 0.27710037727658143 0.06388694856342347 0.3808712461575264 6.069200742024164 0.02976791426460088 0.019172800506996428 4.697995662381825e-08 7.3280873885385125 0.08651966814078715 S(ph)LTLDAAPDHNPPCR ddPTM_PC-9_AZD4547_30min_R2 2 SLTLDAAPDHNPPCR 15 0 B7Z5R6;Q14596-2;Q14596 B7Z5R6 NBR1 Next to BRCA1 gene 1 protein 1 S(0.955)LT(0.045)LDAAPDHNPPCR;S(0.812)LT(0.188)LDAAPDHNPPCR 140.75 2.3647e-05 18195600.0 33034.0 39410.0 43971.0 48783.0 49744.0 48202.0 34931.0 42198.0 40527.0 40517.0 True False 43538.12485011524 52148.51179544583 43387.91580985899 37536.83303983681 42837.90424394179 45187.92132008433 38039.79132968647 35677.26871357332 42669.17448248971 39098.51216241497 1.1135494023214527 1.3337722821477516 1.1097075926988185 0.9600578375951763 1.095640265440112 1.1557452910835582 0.9729217104648233 0.9124968378686682 1.0913247620585211 1.0 15.254826088444073 -5.504447825906246 8.22013153730075 1.0295361712662612 1.2236578605491322 0.4644612174288696 0.08424592120891639 0.1740077357007767 63.2634453805971 0.022608288972404647 0.04426299507696839 3.1300564792217898e-06 5.504447825906246 0.194121689282871 S(ph)LTLDAAPDHNPPCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLTLDAAPDHNPPCR 15 0 B7Z5R6;Q14596-2;Q14596 B7Z5R6 NBR1 Next to BRCA1 gene 1 protein 1 S(0.574)LT(0.426)LDAAPDHNPPCR 106.31 0.00054183 4673000.0 12485.0 18328.0 16473.0 15526.0 18037.0 11117.0 14000.0 13016.0 15451.0 12545.0 True False 14598.463910009816 20147.482714467755 16865.7787942004 14656.12855597116 14502.779329687888 10534.004949639993 12673.81864877744 12674.343791591964 15676.941644579818 14819.309193834632 0.985097464332771 1.3595426379827364 1.1380948041233374 0.9889886474646631 0.9786407139491744 0.7108296892828527 0.8552233091978543 0.8552587455874765 1.0578726335706656 1.0 13.855190577135332 -5.919521317175459 2.0869463062201468 0.8892994584446484 1.1874782104359893 0.4483570645752938 0.12373107302531901 0.2583077565763565 2.2831007290503202 0.03850476756053292 0.06480602065064864 1.2035903105797661e-06 5.919521317175459 0.2981787519913409 S(ph)LTLDAAPDHNPPCR ddPTM_PC-9_Lapatinib_30min_R1 2 SLTLDAAPDHNPPCR 15 0 B7Z5R6;Q14596-2;Q14596 B7Z5R6 NBR1 Next to BRCA1 gene 1 protein 1 S(0.957)LT(0.043)LDAAPDHNPPCR;S(0.83)LT(0.17)LDAAPDHNPPCR 144.08 8.704e-06 8729000.0 40785.0 42076.0 49106.0 42956.0 42965.0 51673.0 41877.0 45553.0 54904.0 33333.0 True False 40203.39842094699 41978.57560714175 45068.69423464171 46115.12753701528 40437.883172440066 49463.06624564626 44045.18615426534 47669.55867940239 48720.13335524884 39094.564636569354 1.0283628630907025 1.073770126292049 1.152812281032134 1.1795790019843024 1.0343607493358338 1.2652159374446168 1.126631964410345 1.2193398013904961 1.2462124545486217 1.0 15.254680421431104 -4.208067541397991 0.7332716431834384 1.1681309114769742 0.7762073000037664 0.19365684002813022 0.08142814405496632 8.690621792508882 1.9540757414530212 0.030771780685208968 3.4108804420286267 6.193447472052952e-05 4.208067541397991 -0.39192361147320787 S(ph)LTNDWEDHLAVK ddPTM_PC-9_AZD4547_30min_R2 2 SLTNDWEDHLAVK 13 0 P07900;P07900-2;P08238 P07900;P08238 HSP90AA1;HSP90AB1 Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta 1 S(0.886)LT(0.114)NDWEDHLAVK;S(0.921)LT(0.079)NDWEDHLAVK 110.6 0.00037334 3923600.0 28416.0 43406.0 35741.0 34612.0 32410.0 41162.0 34489.0 42491.0 35201.0 36213.0 True False 37451.69691048236 57436.1406494068 35267.05098724545 26632.738150069323 27910.430937322177 38588.1336329885 37558.45418595395 35924.99229604351 37061.65299573419 34945.193892379364 1.0717266879623637 1.643606294653644 1.0092103393633274 0.7621287846360248 0.7986915460614661 1.1042472321609744 1.074781679610153 1.0280381447211775 1.0605650983043013 1.0 15.092806431018058 -5.401674571547313 8.384451793775932 0.9718465337007324 1.3560143237450173 0.4524586049999164 0.1665979451282725 0.24465904353592077 15.732302995540072 0.043772142007666846 0.0913901442128639 3.965750872496839e-06 5.401674571547313 0.3841677900442849 S(ph)LTNDWEDHLAVK ddPTM_PC-9_Lapatinib_30min_R1 1 SLTNDWEDHLAVK 13 0 P07900;P07900-2;P08238 P07900;P08238 HSP90AA1;HSP90AB1 Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta 1 S(0.781)LT(0.219)NDWEDHLAVK 133.96 2.5219e-05 1454800.0 9821.7 14194.0 12616.0 14154.0 17194.0 14106.0 14092.0 19283.0 16270.0 10612.0 True False 9681.640756920815 14161.13466507676 11578.761179168323 15194.93237635986 16182.682724704619 13502.719262692057 14821.614807314438 20178.95857605244 14437.501269304563 12446.270060398832 0.7778748741541105 1.137781407309667 0.9302996900259521 1.2208422525481462 1.30020340601432 1.0848807873496658 1.1908479195283899 1.621285612326318 1.159986180537844 1.0 13.60342583496669 -3.974464476043598 0.5344961890857848 1.266724892935132 3.630658813256321e-11 0.34027097493922465 0.17505840958468527 10.103905483892742 1.1536219409850346 0.09457524175149393 9.624636830144388 0.00010605606854352139 3.974464476043598 -1.2667248928988255 S(ph)LTNLSFLTDSEK ddPTM_PC-9_AZD4547_30min_R2 2 SLTNLSFLTDSEK 13 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6 Q8NEY1-2 NAV1 Neuron navigator 1 1 S(0.999)LT(0.001)NLSFLTDSEK;S(1)LTNLSFLTDSEK 276.75 9.498999999999998e-69 12479600.0 29806.0 29846.0 37050.0 47865.0 39430.0 39618.0 40363.0 44552.0 33449.0 37713.0 True False 39283.687996686305 39493.13582965934 36558.692791960064 36830.463756878176 33955.82511134261 37140.680197068614 43955.22880650813 37667.51210311198 35217.04585251311 36392.67934894383 1.0794392910734225 1.0851945098899538 1.004561726313813 1.0120294635010723 0.9330399882285133 1.020553607525094 1.2078041406364266 1.0350299229673274 0.9676958795707676 1.0 15.151360650600855 -7.071489253387109 24.999999112513247 1.0639268184252342 1.0199032295410064 0.03132527810492325 0.07108644304222082 458.976327414923 160502.81762982777 0.028667514843784495 0.022205769292671474 8.482243714968517e-08 7.071489253387109 -0.04402358888422775 S(ph)LTNLSFLTDSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLTNLSFLTDSEK 13 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6 Q8NEY1-2 NAV1 Neuron navigator 1 1 S(0.853)LT(0.146)NLS(0.001)FLTDSEK;S(0.984)LT(0.016)NLSFLTDSEK;S(0.991)LT(0.009)NLSFLTDSEK 207.66 5.9654e-10 8939300.0 39127.9 36258.1 32148.2 43505.9 46556.0 37066.9 42395.0 36474.0 32593.8 32176.7 True False 45751.48065874834 39857.564546565 32914.735010727425 41068.405471030856 37433.68600504237 35123.04651145189 38379.03868677995 35516.59614739748 33070.422663588506 38010.080999382946 1.2036670129561435 1.0486050936648108 0.8659475103792007 1.080460877515561 0.9848357335952551 0.9240455581250162 1.0097068377045288 0.9343993807320237 0.8700434672613659 1.0 15.214094479131953 -4.873154120494657 3.374842966916341 0.9617238402510875 1.2134405805802873 0.5911959983612067 0.0623054636114205 0.18381438259680632 3.5299641361285023 0.01564956462501706 0.10464797580652961 1.3392013532671679e-05 4.873154120494657 0.2517167403291998 S(ph)LTNLSFLTDSEK ddPTM_PC-9_Lapatinib_30min_R1 2 SLTNLSFLTDSEK 13 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6 Q8NEY1-2 NAV1 Neuron navigator 1 1 S(0.96)LT(0.04)NLSFLTDSEK;S(0.977)LT(0.023)NLSFLTDSEK 169.15 0.00025739999999999997 8748700.0 42501.0 36268.0 44008.0 46342.0 43817.0 40233.0 37319.0 39554.0 47399.0 37286.0 True False 41894.92794627116 36184.02367429928 40389.83211579262 49750.14527238018 41239.770207536494 38512.328377703765 39251.195216730586 41391.82323897619 42060.42548640242 43730.83541952798 0.9580180105034763 0.8274258501391748 0.9236007436930088 1.1376445200533323 0.9430364138234801 0.8806675657631298 0.8975633518129175 0.9465134347854853 0.9618024691936334 1.0 15.416363289004417 -6.151647116378813 0.006364942279155927 1.879275350787737 7.226319664711627e-08 0.03621872092678713 0.07679835860885459 46886.94810451354 80.47109961416508 11568.411866446135 12191.387502854313 7.05265896183132e-07 6.151647116378813 -1.8792752785245406 S(ph)LTNLSFLTDSEKK ddPTM_PC-9_AZD4547_30min_R2 2 SLTNLSFLTDSEKK 14 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6 Q8NEY1-2 NAV1 Neuron navigator 1 1 S(0.999)LT(0.001)NLSFLTDSEKK;S(0.968)LT(0.032)NLSFLTDSEKK 94.281 0.0015975 19863600.0 48337.0 45880.0 52186.0 60625.0 57567.0 53747.0 54994.0 52403.0 51303.0 52018.0 True False 63707.1605279415 60709.81276769992 51493.979542273344 46648.84289691302 49574.81572875119 50386.19159351421 59888.35946250543 44305.32045114424 54014.771842849674 50196.86565304695 1.2691461847095322 1.2094343337553553 1.025840535506576 0.929317842658597 0.9876077935105496 1.0037716685694251 1.1930697003363637 0.8826312136175161 1.0760586570522452 1.0 15.615309663088464 -5.213656988753678 3.4767394926784543 1.00909110963235 1.2557471509376614 0.577054531537174 0.07849808613277331 0.16453747995429638 4.045305093083266 0.0204972898659227 0.061565867379590196 6.114247452082172e-06 5.213656988753678 0.24665604130531138 S(ph)LTNLSFLTDSEKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLTNLSFLTDSEKK 14 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6 Q8NEY1-2 NAV1 Neuron navigator 1 1 S(0.983)LT(0.017)NLSFLTDSEKK;S(0.89)LT(0.1)NLS(0.011)FLTDSEKK 87.148 0.010793 7240600.0 23272.7 24345.8 22164.9 26659.2 29351.1 34237.0 26718.0 30210.8 34572.2 26864.7 True False 27212.308453222704 26762.69012821306 22693.395276851355 25165.571454292563 23599.962653634317 32441.551449206094 24187.077618431136 29417.798510988534 35077.753020823424 31735.05744915181 0.857484140270558 0.8433162653350846 0.7150891506408125 0.7929896296742066 0.7436558982585071 1.0222622568491102 0.7621564150997808 0.9269811015191589 1.105331322529588 1.0 14.953789833845939 -8.01646686050739 4.314475002209465 1.0476679370297586 0.8207464873593867 0.5546860982917166 0.083513882934986 0.15438563132979788 6.838035774131617 0.05675809087248314 0.022127326076041304 9.627934775724801e-09 8.01646686050739 -0.22692144967037187 S(ph)LTNLSFLTDSEKK ddPTM_PC-9_Lapatinib_30min_R1 2 SLTNLSFLTDSEKK 14 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6 Q8NEY1-2 NAV1 Neuron navigator 1 1 S(0.99)LT(0.01)NLSFLTDSEKK;S(0.988)LT(0.011)NLS(0.001)FLTDSEKK 92.977 0.0018039000000000002 18178000.0 54606.0 39448.0 44446.0 42238.0 41575.0 43886.0 36236.0 37599.0 41391.0 36035.0 True False 53827.308426486 39356.6605796779 40791.82144652147 45344.32342183749 39129.64023959491 42009.09808326267 38112.12277589029 39345.98680189783 36729.109713447164 42263.60173638068 1.2736091155276819 0.9312188020596343 0.9651761745475588 1.072893022811279 0.9258472688547971 0.9939781835276255 0.901771766013099 0.9309662495714047 0.8690482638594097 1.0 15.367128099633385 -4.758828741718177 24.99821504482482 0.9551041064779435 1.273609537482333 0.754808190291866 0.054554172859900565 35.51199812077542 339977.6316097535 0.013881697970171622 0.0924407790950252 1.7424938673269997e-05 4.758828741718177 0.31850543100438955 S(ph)LTNSHLEK ddPTM_PC-9_AZD4547_30min_R2 3 SLTNSHLEK 9 0 F8VX12;F8VX04;Q9H2H9 F8VX12 SLC38A1 Sodium-coupled neutral amino acid transporter 1 1 S(0.883)LT(0.093)NS(0.024)HLEK;S(0.89)LT(0.08)NS(0.029)HLEK;S(0.736)LT(0.236)NS(0.028)HLEK 82.85 0.0085994 55460900.0 120945.0 172769.0 239316.0 182713.0 197553.0 122604.0 137022.0 278193.0 138920.0 145103.0 True False 159402.99418772152 228613.20056806336 236142.51347370335 140591.34073770983 170126.17596299964 114937.5524983945 149216.69255321383 235204.66408917774 146263.02758919905 140022.98813591606 1.13840588827453 1.6326833444388107 1.6864553214968314 1.0040589949504726 1.2149874690423212 0.820847733850874 1.0656585360710464 1.679757497110915 1.04456439286402 1.0 17.095304174086564 -5.766598791699124 24.999746661525098 1.136286453716813 1.500531710512656 0.3067958678465422 0.25173052121993683 159.58129674633392 773250.1604234283 0.07281562479557284 0.11179249956519803 1.7115957849503439e-06 5.766598791699124 0.3642452567958432 S(ph)LTNSHLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLTNSHLEK 9 0 F8VX12;F8VX04;Q9H2H9 F8VX12 SLC38A1 Sodium-coupled neutral amino acid transporter 1 1 S(0.999)LT(0.001)NSHLEK;S(1)LTNSHLEK;S(0.985)LT(0.014)NS(0.001)HLEK;S(0.999)LT(0.001)NSHLEK 116.98 0.0010687000000000001 68417800.0 160067.0 150648.0 184996.0 122575.0 255709.0 123019.0 116831.9 136470.0 124782.0 105799.2 True False 187163.18163264226 165603.33784205292 189407.0062412372 115707.52014351178 205604.65707241555 116567.66707742757 105764.73664229315 132887.80710191713 126606.70068564883 124979.75745399378 1.4975479665300102 1.325041280409054 1.5155014707958583 0.9258100871743554 1.6451036652723585 0.9326923771662561 0.8462549359741408 1.0632746439025087 1.01301765393691 1.0 16.931334919839117 -6.787502363560865 24.97969050422771 0.967202829504824 1.3607426146507964 0.5507496200023896 0.1849843513764813 173.6687101798584 166448.9841760848 0.06265314096255459 0.05527245037999372 1.6311640319196482e-07 6.787502363560865 0.39353978514597243 S(ph)LTNSHLEK ddPTM_PC-9_Lapatinib_30min_R1 3 SLTNSHLEK 9 0 F8VX12;F8VX04;Q9H2H9 F8VX12 SLC38A1 Sodium-coupled neutral amino acid transporter 1 1 S(0.986)LT(0.014)NSHLEK;S(0.987)LT(0.013)NSHLEK;S(0.938)LT(0.047)NS(0.015)HLEK 104.81 0.001518 75744000.0 358338.0 359935.0 173374.0 96782.0 144726.0 106099.0 89130.0 78926.0 204823.0 63357.0 True False 353228.03440885845 359101.5926218401 159119.8589629934 103899.67113528778 136213.50122226356 101561.393098849 93744.7152835606 82593.1900935286 181753.67685819132 74308.1730321041 4.753555631844828 4.832598864551465 2.141350708410598 1.398226694261464 1.8330890891828802 1.3667593880281572 1.2615666818111533 1.1114953675128716 2.445944630877501 1.0 16.181233278663456 -5.3245542630929 3.3494751204460878 1.5039625267674377 4.872011007104108 0.9158127261185993 0.39454393557169104 0.05746874607449822 1.2668289498398646 0.10331895405550247 0.2609201666810147 4.736371257025945e-06 5.3245542630929 3.3680484803366704 S(ph)LTPAVPVESKPDKPSGK ddPTM_PC-9_AZD4547_30min_R2 1 SLTPAVPVESKPDKPSGK 18 2 H0Y944;P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;F8W7E0;P20810-2;E9PCH5;E9PSG1;P20810-3;H0YA91;E7EQK6 H0Y944;P20810-6 CAST Calpastatin 1 S(0.965)LT(0.035)PAVPVESKPDKPSGK 60.669 0.0081658 20336000.0 127920.0 125800.0 147840.0 210680.0 217150.0 205080.0 162940.0 224260.0 209200.0 215150.0 True False 168595.89909870905 166462.38984691928 145879.5450030602 162110.9809735527 187002.47078184228 192256.31518034253 177441.3443433945 189605.76998213114 220257.88490973553 207617.66398656316 0.8120498798677382 0.8017737347131147 0.7026355185871921 0.7808149743176207 0.9007059765104809 0.9260113589987469 0.8546543725435537 0.9132448864967591 1.0608822037608054 1.0 17.6635696669848 -7.142991056027998 0.5758660024972336 1.0159953411739695 0.762288377071214 0.7158005059589874 0.05416215828900314 0.502063584549935 0.34820106493687664 0.052848969104063975 0.04465296657231065 7.194637946731352e-08 7.142991056027998 -0.2537069641027555 S(ph)LTPAVPVESKPDKPSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLTPAVPVESKPDKPSGK 18 2 H0Y944;P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;F8W7E0;P20810-2;E9PCH5;E9PSG1;P20810-3;H0YA91;E7EQK6 H0Y944;P20810-6 CAST Calpastatin 1 S(0.929)LT(0.07)PAVPVESKPDKPSGK 55.206 0.012894999999999998 9429700.0 69767.0 89090.0 73372.0 77702.0 99486.0 86392.0 68117.0 78381.0 72621.0 60861.0 True False 81577.17513893933 97934.2664247017 75121.46674485967 73348.60885328302 79992.43246622678 81861.451435576 61664.464635626675 76323.5818015341 73682.94473956594 71894.61752458902 1.1346770863763025 1.3621919108368123 1.0448830431452956 1.020223924665803 1.1126345089584513 1.138631155629671 0.8577062756406837 1.0616035585060357 1.0248742851210701 1.0 16.133596145189628 -5.323901311478256 9.4946877957002 1.034518093018863 1.2481776695221858 0.4937930744025547 0.087411424356185 0.3545153072992157 52.27792530862165 0.022588816502357268 0.04715787411765136 4.743497636467271e-06 5.323901311478256 0.21365957650332268 S(ph)LTPAVPVESKPDKPSGK ddPTM_PC-9_Lapatinib_30min_R1 2 SLTPAVPVESKPDKPSGK 18 2 H0Y944;P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;F8W7E0;P20810-2;E9PCH5;E9PSG1;P20810-3;H0YA91;E7EQK6 H0Y944;P20810-6 CAST Calpastatin 1 S(0.899)LT(0.101)PAVPVESKPDKPSGK;S(0.81)LT(0.189)PAVPVESKPDKPSGK 55.707 0.012462 31016000.0 282010.0 221222.0 234463.0 242092.0 223495.0 224347.0 176764.0 164532.0 215763.0 203238.0 True False 277988.48568569956 220709.7740508387 215186.35719335338 259896.25327523748 210349.46350807583 214752.20178840024 185915.97500710527 172176.75737359622 191461.49885488398 238367.41750238813 1.1662184731389074 0.925922579366903 0.9027507175606225 1.0903178630637875 0.8824589606755647 0.9009293469660077 0.7799554861781504 0.7223166621414239 0.8032200913237892 1.0 17.862827521393555 -6.687694529147849 1.7215078895988691 0.8079678903836112 1.005727453473355 0.3969622924638232 0.10136911709795858 0.34815044574364495 2.1309072065756074 0.04094001520072987 0.03950237293025968 2.052605417670734e-07 6.687694529147849 0.19775956308974374 S(ph)LTPPPSSTESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLTPPPSSTESK 12 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 S(0.981)LT(0.019)PPPSSTESK;S(0.924)LT(0.076)PPPSSTESK 126.34 0.00026635 65257000.0 123026.0 134171.0 127887.0 150070.0 146446.0 148453.0 145406.0 113993.0 116458.0 108728.0 True False 143851.8719257405 147490.61017475158 130936.31109414852 141662.0644335045 117750.95757140697 140667.8633434295 131632.09103172383 111000.80453556725 118160.97793310991 128439.5257096257 1.119996910070805 1.1483272719972224 1.0194393849613514 1.102947582925307 0.9167813172840322 1.0952069665956994 1.0248565642426604 0.8642262101350042 0.919973639580752 1.0 16.970729717163472 -5.839399349570483 0.4653545168287306 0.9370528388459568 1.1792575206029128 0.46168909340187636 0.06737980355910653 1.8001418631611608 0.5997094315555597 0.05654173978929762 0.21863834393309325 1.4474402674514016e-06 5.839399349570483 0.24220468175695598 S(ph)LTQPITTEEVVIAATLQASAHQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLTQPITTEEVVIAATLQASAHQK 24 0 O95425-2;O95425-4 O95425-2 SVIL Supervillin 1 S(0.499)LT(0.499)QPIT(0.001)TEEVVIAATLQASAHQK;S(0.467)LT(0.467)QPIT(0.033)T(0.033)EEVVIAATLQASAHQK 158.8 1.099e-07 28362800.0 24635.5 27055.0 48760.0 58701.0 63301.0 59638.0 54661.0 46623.0 50753.0 41973.4 True False 28805.80357669579 29740.84159973402 49922.62332332976 55412.173281209725 50897.62346003067 56510.47829330122 49483.114368630275 45399.19565115184 51495.1666097573 49582.84515874841 0.5809631029536289 0.5998211983300547 1.006852736334381 1.1175674389760748 1.0265167982408585 1.1397183463831642 0.9979886029170204 0.9156230447405375 1.0385682073081175 1.0 15.597553437957686 -5.26684807527681 5.099391712236473 1.0347381530337978 0.5838657815373876 0.8992400428723656 0.058978088633016845 0.04820749243921178 4.1154355393128625 0.016540631171111927 0.04008812095922742 5.409435224990132e-06 5.26684807527681 -0.45087237149641024 S(ph)LTQPITTEEVVIAATLQASAHQK ddPTM_PC-9_Lapatinib_30min_R1 1 SLTQPITTEEVVIAATLQASAHQK 24 0 O95425-2;O95425-4 O95425-2 SVIL Supervillin 1 S(0.458)LT(0.404)QPIT(0.069)T(0.069)EEVVIAATLQASAHQK 88.29299999999999 0.00031756 0.0 2252.7 1010.8 2988.3 2422.1 1093.6 2536.9 2116.8 673.36 3251.4 1144.0 True False 2220.5760849054154 1008.4595547033666 2742.6135091715832 2600.229313888741 1029.2765981003242 2428.40270080274 2226.3975464180526 704.646763821536 2885.1930932401265 1341.7388757158178 1.6549986924398667 0.7516064213056012 2.0440739690935756 1.9379548144205918 0.7671213950264392 1.8098921815224196 1.6593374364518352 0.5251742917902762 2.1503387473221087 1.0 10.389888211516382 -9.521608496917572 12.456695062557214 1.000040341788587 1.4528427752273296 0.060479729229811485 0.5572158501774047 0.0 0.0 0.5154436313480052 0.12501344329998568 3.008787409518072e-10 9.521608496917572 0.4528024334387426 S(ph)LVGSWLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLVGSWLK 8 0 Q6ICG6-2;B0QY16;Q6ICG6-3;Q6ICG6 Q6ICG6-2 KIAA0930 Uncharacterized protein KIAA0930 1 S(0.721)LVGS(0.279)WLK 88.819 0.01069 8738800.0 17730.0 16986.0 22830.0 28257.0 27487.0 23740.0 28070.0 23736.0 23051.0 23604.0 True False 20731.33881653778 18672.257823436783 23374.353783257135 26673.851900430058 22101.119667080482 22495.0326081185 25411.00639079878 23112.955150370828 23388.077266792414 27883.218350838808 0.7435059524222433 0.669659348088671 0.8382946864006452 0.9566274439631762 0.7926315889720678 0.8067588298121183 0.9113369221252159 0.8289199209199437 0.8387868635719675 1.0 14.767109469838484 -1.5228787452803376 0.09095567006538241 1.061794069136259 0.1607651045506719 0.4671815992821111 0.06772200937227753 157.55625126190998 1.033045290438402 1.3217729521377983 17.70666469359708 0.029999999999999995 1.5228787452803376 -0.9010289645855871 S(ph)LVGTPYWMAPELISR ddPTM_PC-9_AZD4547_30min_R2 4 SLVGTPYWMAPELISR 16 0 O96013;O96013-2;O96013-4;O96013-3;M0R1R1 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 S(0.818)LVGT(0.107)PY(0.074)WMAPELISR;S(0.981)LVGT(0.017)PY(0.002)WMAPELISR;S(0.995)LVGT(0.005)PYWMAPELISR;S(1)LVGTPYWMAPELISR 151.73 2.7473000000000003e-05 165047000.0 60784.1 61180.0 75357.8 90860.0 85923.3 82083.5 69673.59999999999 91412.5 68887.0 72324.9 True False 80112.17941217808 80955.23855989276 74358.50633408815 69913.6307730065 73994.33293911818 76950.80576899594 75874.41542435193 77286.79857527673 72528.22618440216 69792.82726498635 1.1478569152674052 1.1599363678523218 1.0654175973093485 1.0017308871520778 1.0601996772272848 1.102560374532937 1.087137724572688 1.1073745197602842 1.0391931238009626 1.0 16.09079115522563 S(ph)LVGTPYWMAPELISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLVGTPYWMAPELISR 16 0 O96013;O96013-2;O96013-4;O96013-3;M0R1R1 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 S(0.842)LVGT(0.158)PYWMAPELISR;S(0.589)LVGT(0.35)PY(0.061)WMAPELISR;S(0.825)LVGT(0.166)PY(0.009)WMAPELISR 139.49 1.6299e-05 268694000.0 93110.0 89779.0 94584.0 98649.0 118639.0 96510.0 104725.0 80238.0 93234.0 71776.0 True False 108871.68399367353 98691.66579125948 96839.24127181749 93122.01635437325 95392.5396071877 91448.84570385503 94804.68985665825 78131.83751918843 94597.37086860102 84788.42062149679 1.284039532705611 1.1639757536212172 1.1421281415786322 1.0982869555983168 1.125065650568356 1.078553475032764 1.1181325133991469 0.9214918375231453 1.115687380130505 1.0 16.371579631925073 -1.5228787452804138 0.2610865858160401 1.0107434912013884 2.7055651867859263 0.6428496174519466 0.05446063084344399 31.3224614439491 0.43283275058763815 0.06378431009011333 23.65184731945471 0.029999999999994736 1.5228787452804138 1.6948216955845379 S(ph)LVGTPYWMAPELISR ddPTM_PC-9_Lapatinib_30min_R1 5 SLVGTPYWMAPELISR 16 0 O96013;O96013-2;O96013-4;O96013-3;M0R1R1 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 S(0.987)LVGT(0.007)PY(0.005)WMAPELIS(0.001)R;S(0.971)LVGT(0.019)PY(0.01)WMAPELISR;S(0.967)LVGT(0.033)PYWMAPELISR;S(0.999)LVGT(0.001)PYWMAPELISR;S(1)LVGTPYWMAPELISR 163.9 2.1923000000000003e-05 57785810.0 84544.6 86774.29999999999 82311.5 78999.20000000001 94097.59999999999 86592.3 77980.8 77573.3 93292.20000000001 66019.7 True False 83338.97850041903 86573.37943974709 75544.16620157844 84809.06470160598 88562.96417099943 82888.94918551025 82018.26426101512 81177.63871325481 82784.65002558187 77431.11717927946 1.07629828338213 1.1180696158535357 0.9756305856554789 1.0952840123079208 1.1437645148002442 1.0704862877490717 1.0592416492082226 1.048385218636338 1.0691392949155978 1.0 16.240625837114848 -9.079440776096636 0.6383267895184107 0.998509071586998 1.0782330085033762 0.22416640870822946 0.041900628880529804 3.123767602892788 2.0835575577188066 0.056829740485255784 0.017476735176996903 8.328354904160983e-10 9.079440776096636 0.07972393691637825 S(ph)LVGTPYWMAPEVISR ddPTM_PC-9_AZD4547_30min_R2 3 SLVGTPYWMAPEVISR 16 0 Q9NQU5-2;Q9NQU5 Q9NQU5-2 PAK6 Serine/threonine-protein kinase PAK 6 1 S(0.489)LVGT(0.47)PY(0.04)WMAPEVISR;S(0.997)LVGT(0.001)PY(0.002)WMAPEVISR;S(1)LVGTPYWMAPEVISR 168.41 3.928e-05 11750300.0 19546.3 22140.9 23657.3 31110.0 30290.0 30914.5 17897.6 24672.9 23140.699999999997 23206.4 True False 25761.61681170331 29297.512936102175 23343.58874459477 23938.07014470867 26084.756343458448 28981.4114279438 19490.451727754622 20860.27023183857 24363.870159324626 22393.950999478413 1.1503828338421984 1.308277978137246 1.0424059937051071 1.0689525106697886 1.1648126024776064 1.294162491854109 0.8703444840175181 0.9315136142043196 1.0879665745402451 1.0 14.45082146711856 -7.266843368982537 24.995390651108917 0.966748970707221 1.16688328738631 0.5189817817801239 0.09374900582629757 392.8444151738652 1817036.7019815857 0.04003588133090368 0.027868109632624954 5.4094938454263216e-08 7.266843368982537 0.20013431667908899 S(ph)LVGTPYWMAPEVISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLVGTPYWMAPEVISR 16 0 Q9NQU5-2;Q9NQU5 Q9NQU5-2 PAK6 Serine/threonine-protein kinase PAK 6 1 S(0.889)LVGT(0.11)PY(0.001)WMAPEVISR;S(0.993)LVGT(0.006)PYWMAPEVISR 115.38 0.00015601 6930400.0 32186.4 35322.1 32313.0 34015.0 35302.0 29226.7 33976.1 34669.6 32229.4 25847.0 True False 37634.92180962278 38828.644652373514 33083.4644677349 32109.24982811793 28384.8265175274 27694.00040133518 30757.63784233765 33759.559735477626 32700.69400296557 30532.856495260567 1.2326040249612618 1.2717003618184448 1.0835365001918589 1.051629408899297 0.9296485745424247 0.9070229117159069 1.0073619494825836 1.1056797041153985 1.0710001538192637 1.0 14.89807494645309 -5.436710039155404 2.299083933910867 1.0061243144453254 1.2583192961961809 0.730625753308251 0.05775819387598421 0.1769404521346101 1.7997479025772294 0.01878877751659034 0.050355314165472724 3.6583896595918586e-06 5.436710039155404 0.25219498175085553 S(ph)LVNNPR ddPTM_PC-9_AZD4547_30min_R2 1 SLVNNPR 7 0 A0A0A0MSF5;C9JJ37-2;C9JJ37 A0A0A0MSF5 BTBD19 BTB/POZ domain-containing protein 19 1 S(1)LVNNPR 82.75 0.022022999999999997 35573000.0 88026.0 110150.0 133530.0 190400.0 154020.0 115170.0 133500.0 158060.0 141930.0 149880.0 True False 116016.4369454574 145753.8333993493 131759.304953048 146506.22165067605 132636.98157872146 107968.40169358368 145381.2413762316 133635.45885746702 149432.13004416236 144632.74681992122 0.8021450155399918 1.0077512638325532 0.9109922050854664 1.012953324001289 0.9170605170339785 0.7465003885186013 1.0051751389140269 0.9239640523722704 1.0331832405161796 1.0 17.14203470947824 -8.006962374345404 1.8271515494241 1.0128638879012513 0.9137333403387238 0.18703468404420598 0.08281019919619853 0.6741397436377804 4.065197046598076 0.07130855907246264 0.023630343892218148 9.840963605073632e-09 8.006962374345404 -0.09913054756252748 S(ph)LVNNPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLVNNPR 7 0 A0A0A0MSF5;C9JJ37-2;C9JJ37 A0A0A0MSF5 BTBD19 BTB/POZ domain-containing protein 19 1 S(1)LVNNPR 72.87899999999999 0.037712999999999997 24634000.0 99014.0 105580.0 114740.0 110210.0 160940.0 89570.0 95431.0 84998.0 106720.0 96801.0 True False 115775.11458435835 116061.28464608832 117475.83675387302 104035.29100564109 129404.9623174567 84872.79152102678 86391.08481939143 82766.89256282542 108280.57810559578 114350.2550237058 1.012460484328235 1.014963059085682 1.0273334041058262 0.9097950064394144 1.1316543394733132 0.7422177720848275 0.7554953401851339 0.72380155641688 0.9469203027413299 1.0 16.803100057685526 -6.770038902133927 24.999998429456383 0.8115376026613907 1.0133728028856757 0.4691983274351631 0.09716345070440657 151.70609459224627 441027.79558804265 0.032667101474159625 0.02925110690387816 1.6980915382951253e-07 6.770038902133927 0.20183520022428492 S(ph)LYASSPGGVYATR ddPTM_PC-9_Lapatinib_30min_R1 2 SLYASSPGGVYATR 14 0 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 1 S(0.999)LY(0.001)ASSPGGVYATR;S(0.994)LY(0.006)ASSPGGVYATR 67.846 0.033378 20072600.0 83561.0 56887.0 77330.0 57678.0 79427.0 81695.0 61960.0 66527.0 73597.0 59466.0 True False 82369.40481678936 56755.28164662687 70972.22590243247 61919.83252816762 74755.26001949013 78201.09529034648 65167.98562739161 69618.08728875381 65307.73084923228 69744.6188665357 1.1810144804778793 0.8137585747688232 1.017601458805674 0.8878080278373632 1.07184269172856 1.1212491595945662 0.9343801240364937 0.9981857872358006 0.9363837943427017 1.0 16.089794289909985 -4.718751059265094 24.253864484175605 0.9804592726414401 1.1810180397430772 0.34805185177532094 0.08407595050776137 8821.139980516238 5011302.242012161 0.020902027585030097 9.802872700549013 1.910948314070063e-05 4.718751059265094 0.20055876710163711 S(ph)LYESFVSSSDR ddPTM_PC-9_AZD4547_30min_R2 3 SLYESFVSSSDR 12 0 P18615;P18615-3;A0A0A0MT02;A2ABK4 P18615 NELFE Negative elongation factor E 1 S(1)LYESFVSSSDR;S(0.993)LY(0.007)ESFVSSSDR;S(0.999)LY(0.001)ESFVSSSDR 125.82 0.00028181 9672100.0 2959.6000000000004 7679.1 11020.6 13022.800000000001 13588.8 12891.9 7525.799999999999 8962.699999999999 11085.0 6799.8 True False 3900.691236495763 10161.218902014918 10874.459643267883 10020.594660254324 11702.229679761916 12085.767455010067 8195.581620593583 7577.720657356835 11670.930469523972 6561.741071698036 0.5944597925876933 1.5485552982031057 1.6572521720144329 1.5271243639092897 1.7834031474109409 1.8418537584694017 1.2489949742062505 1.1548338428105462 1.7786331923188472 1.0 12.679862950455728 -10.89882694436249 4.0828382512360655 0.9986536585316012 1.4755102700888545 0.1268062411312052 0.35948731345312207 0.0044378492401533605 0.0006783145925981057 0.3505398157419822 0.08479218365929941 1.2623304419268491e-11 10.89882694436249 0.47685661155725334 S(ph)LYESFVSSSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLYESFVSSSDR 12 0 P18615;P18615-3;A0A0A0MT02;A2ABK4 P18615 NELFE Negative elongation factor E 1 S(1)LYESFVSSSDR;S(0.999)LYES(0.001)FVSSSDR;S(1)LYESFVSSSDR 143.42 4.0441e-05 0.0 4770.599999999999 5633.150000000001 6606.0 6232.5 10215.9 10971.900000000001 6351.6 9852.8 7586.8 6165.2 True False 5578.168356355057 6192.371903808606 6763.512093394513 5883.313231037626 8214.16773045176 10396.514249073942 5749.930466398198 9594.174439904533 7697.742597184531 7282.9019563036545 0.7659266031347464 0.8502616046408328 0.9286836667546254 0.8078254061824042 1.127870151175392 1.4275235766527554 0.7895108983887109 1.31735597945272 1.0569608987419932 1.0 12.830297708128676 -6.267221682334972 23.257700643554404 1.1346027851183353 0.8455026402499419 0.4053368281635201 0.1664857022434229 176.01987251907948 707990.0284136035 0.04918240711208385 0.057390709294927254 5.404783694247835e-07 6.267221682334972 -0.2891001448683934 S(ph)LYESFVSSSDR ddPTM_PC-9_Lapatinib_30min_R1 4 SLYESFVSSSDR 12 0 P18615;P18615-3;A0A0A0MT02;A2ABK4 P18615 NELFE Negative elongation factor E 1 S(1)LYESFVSSSDR;S(1)LYESFVSSSDR;S(1)LYESFVSSSDR;S(1)LYESFVSSSDR 158.86 0.0001543 11079700.0 26769.199999999997 23465.1 31204.8 24824.0 28304.2 32679.7 26889.399999999998 24872.5 31259.4 25251.7 True False 26387.466299129945 23410.768002641442 28639.261798011394 26649.639770436435 26639.40260419824 31282.065411101492 28281.60156115533 26028.16715152542 27738.637195924974 29616.42269922476 0.8909741249681942 0.7904657574749648 0.967006113090122 0.8998264253951919 0.8994807669629713 1.0562405098276886 0.9549296972282756 0.8788423712026076 0.9365964781644969 1.0 14.85410977082558 -5.271211498723414 24.88712800352282 0.9452888185403034 0.840719939311336 0.38713703824299384 0.0543829411131451 603.2674857795641 1536372.9176284408 0.014546987531153896 0.030902785005971233 5.355357913841861e-06 5.271211498723414 -0.1045688792289674 S(ph)LYYYIQQDTK ddPTM_PC-9_AZD4547_30min_R2 2 SLYYYIQQDTK 11 0 P07355;P07355-2;A6NMY6 P07355 ANXA2;ANXA2P2 Annexin A2;Putative annexin A2-like protein 1 S(0.986)LY(0.014)YYIQQDTK;S(1)LYYYIQQDTK 154.47 0.00041668 9790800.0 33348.0 29328.0 40584.0 40166.6 43365.0 55954.0 62193.0 76052.0 48528.0 52527.0 True False 43951.970318509535 38807.702459701475 40045.82964288548 30906.810937783837 37344.51828438679 52455.18753462506 67728.05651619451 64299.91090110149 51093.091008124466 50688.04571797447 0.8671072182000448 0.765618439417164 0.7900448532914112 0.6097455622918992 0.7367519847217953 1.0348630883597856 1.3361741522454769 1.268541921281848 1.0079909431190865 1.0 15.629357921315904 -6.884781567662071 3.8441624978672735 1.1769889478938884 0.748394372517443 0.7328039196256003 0.11450157392223537 0.11273582761090163 3.1265380325166388 0.04277628068481505 0.03750141667084777 1.3038223828281056e-07 6.884781567662071 -0.4285945753764454 S(ph)LYYYIQQDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLYYYIQQDTK 11 0 P07355;P07355-2;A6NMY6 P07355 ANXA2;ANXA2P2 Annexin A2;Putative annexin A2-like protein 1 S(0.999)LY(0.001)YYIQQDTK;S(1)LYYYIQQDTK 123.95 0.00053626 9098000.0 28198.9 29231.6 29776.9 28444.0 52225.0 28401.5 38337.3 33738.0 30593.9 23715.3 True False 32972.41681633767 32133.520063085736 30486.89422552211 26850.374896692214 41991.886150299375 26912.075342016753 34705.71340598396 32852.41324836583 31041.277909527602 28014.696159788506 1.1769685677928334 1.1470236864181762 1.088246470767801 0.9584389116178413 1.4989234903990616 0.9606413429764616 1.2388395436463648 1.1726849743785994 1.1080355015266368 1.0 14.773896225101902 -8.61867769001853 3.813941320477248 1.0000542746537138 1.153555250249803 0.09671363827217805 0.1439058845681388 1.101936330441886 36.82444439316257 0.13162075254915553 0.03454669741469788 2.4061478509253878e-09 8.61867769001853 0.15350097559608922 S(ph)LYYYIQQDTK ddPTM_PC-9_Lapatinib_30min_R1 2 SLYYYIQQDTK 11 0 P07355;P07355-2;A6NMY6 P07355 ANXA2;ANXA2P2 Annexin A2;Putative annexin A2-like protein 1 S(0.993)LY(0.006)Y(0.001)YIQQDTK;S(1)LYYYIQQDTK 163.99 0.0016117 8206600.0 23602.0 37252.0 41508.0 38383.0 37820.0 37859.0 29370.0 28760.0 44217.0 30370.0 True False 23265.431151923294 37165.74528275608 38095.3724655135 41205.81386193449 35595.50195698084 36239.85882363945 30890.634891486297 30096.294593541897 39236.81583434791 35619.41403451872 0.6531671500653211 1.0434125964772698 1.069511486870484 1.1568358149295213 0.9993286785258538 1.0174187253198343 0.8672415234442159 0.8449407551841146 1.1015570271965611 1.0 15.120376162792816 -9.953854349861693 15.166897350088638 1.0000015159482234 0.9782038486704441 0.00198741185127993 0.14050596490573053 0.0 0.0 0.13777491969539038 0.03341532626265209 1.1121046333211042e-10 9.953854349861693 -0.02179766727777932 S(ph)MAHSPGPVSQASPGTSSAVLFLSK ddPTM_PC-9_AZD4547_30min_R2 2 SMAHSPGPVSQASPGTSSAVLFLSK 25 0 Q8TDZ2-2;Q8TDZ2;Q8TDZ2-4;H0Y6Z4 Q8TDZ2-2 MICAL1 Protein-methionine sulfoxide oxidase MICAL1 1 S(0.5)MAHS(0.421)PGPVS(0.072)QAS(0.007)PGTSSAVLFLSK;S(0.549)MAHS(0.447)PGPVS(0.004)QAS(0.001)PGTSSAVLFLSK 73.696 0.00015013 10543800.0 14848.2 15387.4 60325.0 101329.0 79902.0 62948.0 33423.0 84897.0 46831.0 61479.0 True False 19569.61873825397 20361.076132992708 59525.05108434521 77969.16456744415 68808.98650891425 59011.851608992714 36397.58225106958 71778.11938898131 49306.391052618616 59326.638922751205 0.3298622523304486 0.34320292709493827 1.003344402534793 1.314235324690604 1.1598328804453248 0.9946939971743828 0.6135116182540294 1.2098800925237496 0.8311003614551655 1.0 15.856392430561856 -5.263657632502292 6.630293760796254 1.0249716106590225 0.33242284615726625 0.6817427734862808 0.1856249696676967 0.07380228809642154 19.583430882724354 0.050448005487840765 0.11883633583484282 5.449320700192543e-06 5.263657632502292 -0.6925487645017563 S(ph)MAHSPGPVSQASPGTSSAVLFLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SMAHSPGPVSQASPGTSSAVLFLSK 25 0 Q8TDZ2-2;Q8TDZ2;Q8TDZ2-4;H0Y6Z4 Q8TDZ2-2 MICAL1 Protein-methionine sulfoxide oxidase MICAL1 1 S(0.54)MAHS(0.443)PGPVS(0.017)QAS(0.001)PGTSSAVLFLSK 61.801 0.013285 0.0 3452.7 3564.9 14014.0 12373.0 21855.0 18667.0 16184.0 13760.0 15855.0 10516.0 True False 4037.1739160665525 3918.7997123966657 14348.146908390967 11679.780923807235 17572.6696374302 17688.0696586246 14650.934357986733 13398.81457992512 16086.849380286922 12422.467555389805 0.32498969291450647 0.3154606518329279 1.1550158488573115 0.9402142425994635 1.4145876863092188 1.4238773077696774 1.1793900280005198 1.0785952565528498 1.2949801888037318 1.0 13.600664153456844 -5.271334177384901 5.075710211223132 1.1999038721155022 0.3088207631647218 0.8396458587968552 0.15127757900174027 0.06157689849300873 5.0977026916671795 0.041641834379051765 0.0998497549834185 5.353845356385118e-06 5.271334177384901 -0.8910831089507805 down S(ph)MDAMSSPTKTETVK ddPTM_PC-9_Lapatinib_30min_R1 1 SMDAMSSPTKTETVK 15 1 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 S(0.537)MDAMS(0.383)S(0.079)PT(0.001)KTETVK 75.416 0.025966000000000003 20824000.0 69681.0 49143.0 55716.0 48517.0 50494.0 50423.0 43230.0 43860.0 49481.0 40555.0 True False 68687.33616206958 49029.21240283692 51135.24554997954 52085.10202796745 47524.042195023576 48266.525831753934 45468.237873985476 45897.89571880208 43907.928721970486 47564.877713859285 1.444076794967891 1.0307860496937842 1.0750631139556137 1.0950328168885648 0.9991414774766926 1.014751391186489 0.9559204198424146 0.9649535103383334 0.9231166110866874 1.0 15.537609048644018 -2.261486989454164 1.1740030625119067 0.9949658223336113 199.99999999999997 0.8658815970451768 0.051379928888232715 248.69011334426727 1.0155755111167863 0.016367759686896213 132491.79549167826 0.005476625075286915 2.261486989454164 199.00503417766637 S(ph)MDEFTASTPADLGEAGR ddPTM_PC-9_AZD4547_30min_R2 3 SMDEFTASTPADLGEAGR 18 0 Q7Z5K2;Q7Z5K2-2;Q7Z5K2-3 Q7Z5K2 WAPAL Wings apart-like protein homolog 1 S(0.976)MDEFT(0.023)AS(0.001)TPADLGEAGR;S(0.978)MDEFT(0.021)ASTPADLGEAGR;S(1)MDEFTASTPADLGEAGR 130.95 3.6139e-05 8334600.0 16318.599999999999 17785.5 22810.7 26588.6 23352.1 24332.5 22558.5 29392.5 24453.0 22090.199999999997 True False 21507.575352033982 23534.315060591263 22508.215213753392 20459.009059775024 20110.064001587194 22810.984928445938 24566.162798394893 24850.56449745734 25745.5356582111 21316.82882173359 1.0089481663476096 1.104025146394985 1.0558894759620683 0.9597585659137078 0.9433891020921443 1.0700927947213696 1.152430457824404 1.165772109222969 1.2077563634588189 1.0 14.379705212419386 -7.080786634525297 4.146080272744853 1.1441404023346309 1.0175968063466503 0.4041153811590026 0.06595851700276198 0.22569868858367495 7.1593704750086244 0.026658602013600853 0.020726027013681352 8.302585668577509e-08 7.080786634525297 -0.1265435959879806 S(ph)MDEFTASTPADLGEAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SMDEFTASTPADLGEAGR 18 0 Q7Z5K2;Q7Z5K2-2;Q7Z5K2-3 Q7Z5K2 WAPAL Wings apart-like protein homolog 1 S(1)MDEFTASTPADLGEAGR;S(0.976)MDEFT(0.022)AS(0.001)T(0.001)PADLGEAGR;S(0.852)MDEFT(0.069)AS(0.039)T(0.039)PADLGEAGR 80.508 0.0031211 8442100.0 14387.1 14490.2 20378.4 21005.3 19650.4 19745.1 21268.5 16531.5 14908.000000000002 10703.3 True False 16822.551871822372 15928.691293604352 20864.29834151236 19828.44114110144 15800.045181576703 18709.63219673801 19253.7937093945 16097.565641572104 15126.0012968349 12643.723562723815 1.3305061430968457 1.2598101512251714 1.650170397826825 1.568243804345706 1.2496354498099234 1.4797565055833464 1.522794579767504 1.2731665289670595 1.1963248976297876 1.0 13.626133777746384 -8.3392805168923 1.5573407668729902 1.010827595645869 1.4372174042809214 0.5488391776400813 0.12654474502595275 0.2916280011354813 1.4222070870209078 0.12518796998657486 0.03747962392569094 4.578460619982053e-09 8.3392805168923 0.4263898086350524 S(ph)MDEFTASTPADLGEAGR ddPTM_PC-9_Lapatinib_30min_R1 2 SMDEFTASTPADLGEAGR 18 0 Q7Z5K2;Q7Z5K2-2;Q7Z5K2-3 Q7Z5K2 WAPAL Wings apart-like protein homolog 1 S(1)MDEFTASTPADLGEAGR;S(1)MDEFTASTPADLGEAGR 163.0 6.9917e-07 4796800.0 16448.0 18630.6 20679.7 15170.3 13567.900000000001 14748.8 14260.8 12965.5 15010.5 10694.5 True False 16213.448503806225 18587.461990360647 18979.49489195047 16285.974468637272 12769.862797517739 14118.028205132036 14999.15444536969 13567.924462884814 13319.859422427553 12543.030075474484 1.2926261362881166 1.4818956726178074 1.5131507122079915 1.2984083088887275 1.018084364039498 1.1255675957229156 1.1958158718520249 1.081710271062358 1.0619331487111723 1.0 13.614598288040257 -6.053293592589079 4.150086907144607 1.0940858687507191 1.4328987788842362 0.8154617855252944 0.07527072963506508 0.09164923388491966 3.256382222080909 0.022875066901433063 0.03130785365564733 8.845174544835595e-07 6.053293592589079 0.3388129101335171 S(ph)MDELNHDFQALALEGR ddPTM_PC-9_AZD4547_30min_R2 3 SMDELNHDFQALALEGR 17 0 Q5T1Z4;Q5T1Z8;Q14671-2;Q14671;Q14671-3;E9PR38;H0YEH2;Q14671-4 Q5T1Z4 PUM1 Pumilio homolog 1 1 S(1)MDELNHDFQALALEGR;S(1)MDELNHDFQALALEGR;S(1)MDELNHDFQALALEGR 101.08 0.00076064 10189800.0 10408.98 5696.120000000001 15772.5 19914.6 17220.5 16830.8 14574.4 17648.7 14390.6 15678.199999999999 True False 13718.819119766076 7537.279396302326 15563.34634443157 15323.596647502914 14829.730822467029 15778.367415337018 15871.493365646056 14921.498941780226 15151.257737007832 15129.310990072672 0.906770911693724 0.49819052574489525 1.0286883754748446 1.0128416725360279 0.9801986906209927 1.0429005938003544 1.0490559270055575 0.9862642754565092 1.0014506111315684 1.0 13.885058666255473 -5.285953599480967 24.99983342498688 1.0134093665659722 0.702480715630081 0.6362709529222297 0.0938114035222334 364.02361318111696 371234.177113128 0.02221192737128526 0.04627158019473775 5.176621366106954e-06 5.285953599480967 -0.3109286509358913 S(ph)MDELNHDFQALALEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SMDELNHDFQALALEGR 17 0 Q5T1Z4;Q5T1Z8;Q14671-2;Q14671;Q14671-3;E9PR38;H0YEH2;Q14671-4 Q5T1Z4 PUM1 Pumilio homolog 1 1 S(1)MDELNHDFQALALEGR;S(1)MDELNHDFQALALEGR;S(1)MDELNHDFQALALEGR 87.429 0.0023018 9600500.0 13636.699999999999 12321.400000000001 18520.6 23002.0 24910.6 18940.8 19742.1 19923.4 22909.6 15174.099999999999 True False 15945.123972897944 13544.587162704229 18962.201343766636 21713.272513490185 20029.546752238348 17947.51110462725 17871.985367573518 19400.43186058724 23244.60955929492 17925.044211890498 0.8895444710993136 0.7556236404549277 1.057860785145966 1.2113371803616966 1.1174057098811414 1.001253380045883 0.9970399601981577 1.0823087313624615 1.29676720930349 1.0 14.12968905686974 -5.341671649060993 5.535108207446407 1.098561598037725 0.8237750890128616 0.5664696388387862 0.09583084907560843 0.1477618576244337 7.642569312581815 0.025969898992929782 0.055819962889541136 4.553321866656453e-06 5.341671649060993 -0.27478650902486346 S(ph)MDELNHDFQALALEGR ddPTM_PC-9_Lapatinib_30min_R1 5 SMDELNHDFQALALEGR 17 0 Q5T1Z4;Q5T1Z8;Q14671-2;Q14671;Q14671-3;E9PR38;H0YEH2;Q14671-4 Q5T1Z4 PUM1 Pumilio homolog 1 1 S(1)MDELNHDFQALALEGR;S(1)MDELNHDFQALALEGR;S(1)MDELNHDFQALALEGR;S(1)MDELNHDFQALALEGR;S(1)MDELNHDFQALALEGR 129.51 1.7043e-05 12937800.0 35363.700000000004 33617.799999999996 40952.9 33583.6 35969.7 39809.799999999996 29091.5 31820.100000000002 39199.59999999999 28859.1 True False 34859.4071530917 33539.960049571484 37585.91064476558 36053.449975605414 33854.032965151084 38107.227655176364 30597.715524197298 33298.57801098617 34784.52825791217 33847.356982666395 1.029900419431378 0.9909181407206379 1.110453340980619 1.0651777033600816 1.0001972379257886 1.1258553415172563 0.9039912788424433 0.983786652176084 1.0276881670768476 1.0 15.046755562925183 -7.261802696978342 24.99999998807146 0.9775154159201158 1.0515569515404757 0.35462554048784634 0.049423118330535434 39.25126318685279 2700699.0939307585 0.01979634345165287 0.014256498725070003 5.47264532532284e-08 7.261802696978342 0.07404153562035987 S(ph)MDFEEAERSEPTQALELT(ph)EDDIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SMDFEEAERSEPTQALELTEDDIK 24 1 K7ER96;O43396 K7ER96 TXNL1 Thioredoxin-like protein 1 2 S(0.391)MDFEEAERS(0.307)EPT(0.307)QALELT(0.996)EDDIK 54.117 0.03802 0.0 5417.4 5153.4 6411.2 6705.6 6872.5 5072.9 6848.2 5841.7 6729.9 5671.4 True False 6334.458821472743 5664.995494365898 6564.067322611395 6329.906971848519 5525.8829596540445 4806.868193669937 6199.48891932555 5688.3615647927745 6828.312055780061 6699.5799252223 0.9455008959031947 0.8455747311915123 0.9797729702274717 0.9448214727639787 0.8248103644305265 0.7174879988479934 0.925354871278716 0.8490624230599098 1.0192149555635743 1.0 12.709854923695476 -8.266623178266565 24.53907952120891 1.0096075073995567 0.8778326521322299 0.34268266668146496 0.07231276801548109 428.45969400148624 2028197.4794337524 0.06649211611757068 0.01922529248381702 5.412237196717288e-09 8.266623178266565 -0.1317748552673268 S(ph)MDLGIADETK ddPTM_PC-9_AZD4547_30min_R2 3 SMDLGIADETK 11 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-8 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(1)MDLGIADETK;S(1)MDLGIADETK;S(1)MDLGIADETK 114.87 0.0012465999999999998 33688400.0 223354.0 259702.0 281422.0 294969.0 325430.0 337928.0 356133.0 406698.0 355501.0 347195.0 True False 294375.92594819434 343645.59275059274 277690.1604021318 226968.4542756212 280249.6618306929 316797.30873933516 387828.1470789633 343852.16909030906 374292.057090324 335039.80872793304 0.8786296979629679 1.0256858552281707 0.8288273607141065 0.6774372727150447 0.836466755681167 0.9455512464090153 1.1575584064217774 1.0263024277498083 1.1171569686343317 1.0 18.353972998193107 -7.020090653833346 4.124779552758312 1.0767408733682136 0.8502276960338079 0.5880279613627353 0.08894779502217978 0.16841268967244263 6.583500130509921 0.03737555961365871 0.030221705185798226 9.547932634250084e-08 7.020090653833346 -0.22651317733440568 S(ph)MDLGIADETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SMDLGIADETK 11 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-8 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(1)MDLGIADETK;S(1)MDLGIADETK;S(1)MDLGIADETK;S(1)MDLGIADETK 113.95 0.0013265999999999998 30479600.0 180061.0 256397.0 231926.0 261596.0 288380.0 220965.0 239461.0 221273.0 198712.0 190749.0 True False 210541.77093314205 281850.39969125926 237455.995424253 246939.62422567554 231874.00915315142 209377.20641334914 216777.52053249223 215464.81820812283 201617.7870738295 225330.2837317466 0.9343696171074363 1.2508323116780844 1.0538130582879925 1.0959007379569745 1.029040594601989 0.9292013614229082 0.962043436605102 0.9562177557306567 0.8947656024516146 1.0 17.781681695038834 -6.536140759822309 2.8010432417225286 0.9462967818913389 1.0935711719145333 0.40915646084770485 0.07627882092223012 0.24502394952569065 3.9067947827234786 0.02515125360657425 0.02662042753828122 2.909773874133308e-07 6.536140759822309 0.14727439002319442 S(ph)MDLGIADETK ddPTM_PC-9_Lapatinib_30min_R1 4 SMDLGIADETK 11 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-8 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(1)MDLGIADETK;S(1)MDLGIADETK;S(1)MDLGIADETK;S(1)MDLGIADETK 110.98 0.0016461 35963300.0 128463.0 186075.0 169446.0 156239.0 179401.0 161272.0 147124.0 161340.0 146249.0 169928.0 True False 126631.0940627709 185644.15476991408 155514.8039604754 167729.33725802487 168848.98589593652 154374.77250339382 154741.3608367394 168836.44540062745 129776.89754975562 199299.82838517238 0.6353798449742774 0.9314817592874843 0.7803057595208922 0.8415929838828887 0.8472108945804724 0.7745855766872255 0.7764249577660546 0.8471479718202739 0.6511641209190867 1.0 17.60458094232594 -11.985070152488268 2.43038544118143 3.7135914785103723 0.7957244568348407 0.35294691213182705 0.08572884335625591 5664150.075307059 1069255.07340855 84965071.0449026 0.020205364134731917 1.0349749715226171e-12 11.985070152488268 -2.917867021675532 S(ph)MDLGIADETKLNTVDDQK ddPTM_PC-9_AZD4547_30min_R2 1 SMDLGIADETKLNTVDDQK 19 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-8 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.993)MDLGIADET(0.007)KLNTVDDQK 64.377 0.017263999999999998 5657500.0 18187.0 11714.0 16872.0 27493.0 32750.0 22730.0 22056.0 17864.0 18873.0 29448.0 True False 23970.08768689973 15500.321420244922 16648.26625603105 21154.913612615743 28203.22780614937 21308.689506773924 24018.9412718664 15103.529273882032 19870.58825000685 28417.03448327361 0.8435112291892607 0.5454587961797519 0.5858551590184504 0.7444448021157034 0.9924761087491348 0.7498562004883483 0.8452303946776731 0.5314956169255464 0.6992491866701561 1.0 14.794468386645827 -5.952098672700626 8.138828686252564 0.7870690018846751 0.6492438712063203 0.15585200776493713 0.14760517393526876 0.5098297804891954 76.53740053891369 0.042771634030136535 0.06348386123928543 1.1166095227181032e-06 5.952098672700626 -0.13782513067835478 S(ph)MDLGIADETKLNTVDDQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SMDLGIADETKLNTVDDQK 19 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-8 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.999)MDLGIADETKLNT(0.001)VDDQK 62.475 0.028976 0.0 12905.0 9243.0 9735.8 21728.0 19240.0 20765.0 14322.0 24263.0 19350.0 16861.0 True False 15089.561614631706 10160.583955141065 9967.938395227113 20510.650603126454 15470.060115495635 19676.04684530669 12965.316477699327 23626.12195877349 19632.957143396525 19917.765828397445 0.7575930827100095 0.5101266900454653 0.5004546434126401 1.0297666304462578 0.7766965556668729 0.987864151774185 0.6509423089618931 1.1861833381477411 0.9857007714893977 1.0 14.28176820923159 -5.760142571525003 24.99720065929615 0.9355478313040507 0.5814649493138583 0.5354987341715716 0.1516604227456965 26.382320234920094 508520.40753226785 0.041582473215453664 0.067241005432254 1.7372304317924197e-06 5.760142571525003 -0.35408288199019244 S(ph)MDSSDLSDGAVTLQEYLELKK ddPTM_PC-9_AZD4547_30min_R2 2 SMDSSDLSDGAVTLQEYLELKK 22 1 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QLH1 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 S(0.969)MDS(0.025)S(0.005)DLSDGAVTLQEYLELKK;S(0.944)MDS(0.044)S(0.011)DLSDGAVTLQEYLELKK 130.36 4.3624e-06 19139100.0 29496.0 36750.0 41408.0 46498.0 42480.0 44496.0 36704.0 47849.0 41626.0 42808.0 True False 38875.11444508686 48628.71881458093 40858.902864493444 35778.60448693872 36582.38525817483 41713.65808593983 39970.58489493033 40455.036510634876 43826.26537883674 41309.304949741134 0.9410740387034876 1.1771855971371328 0.9890968370008726 0.8661148990637502 0.8855725193799 1.009788427490868 0.9675927722231213 0.9793201933524275 1.0609296242616006 1.0 15.334179165863128 -5.505110170494971 24.992158595609535 0.9617477277589533 1.0651326813018542 0.18523884562570248 0.0753961888257016 1034.2269344297304 1454676.5787091553 0.01979873239113151 0.03989698291192028 3.1252864534539638e-06 5.505110170494971 0.10338495354290089 S(ph)MDSSDLSDGAVTLQEYLELKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SMDSSDLSDGAVTLQEYLELKK 22 1 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QLH1 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 S(0.322)MDS(0.322)S(0.322)DLS(0.033)DGAVT(0.001)LQEYLELKK 52.464 0.009107299999999999 14013000.0 198380.0 192560.0 228590.0 246420.0 262960.0 227230.0 239760.0 218340.0 208150.0 178090.0 True False 231961.81581639955 211676.08421529373 234040.45253240215 232613.88630441908 211434.8756741548 215313.6587844467 217048.19708791949 212608.80635035265 211193.79996888846 210376.30724033533 1.1026042754491587 1.0061783429512978 1.1124848401537573 1.1057038188177692 1.0050317854120814 1.0234691425516416 1.0317140743418514 1.010611932205212 1.0038858592931723 1.0 17.68261271066602 -6.271322650585277 24.933591948430255 1.014496674162634 1.0785412156663061 0.5737993879128047 0.029171486838076462 534.2480759559086 1347802.3477927304 0.009154566008927624 0.010516275011350933 5.353987457020039e-07 6.271322650585277 0.06404454150367211 S(ph)MEAHNILSKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SMEAHNILSKR 11 1 Q9NP77-2;Q9NP77 Q9NP77-2 SSU72 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 1 S(1)MEAHNILSKR 72.34 0.026431 31125000.0 132380.0 151910.0 145990.0 169230.0 176820.0 165790.0 190100.0 160310.0 152840.0 126970.0 True False 154789.3193758187 166990.62086178522 149470.95527015836 159748.59175106275 142173.39031299078 157095.68054338513 172092.351795185 156102.03236248507 155074.99585512755 149988.65590603292 1.0320068437228571 1.113355005770596 0.9965484013924434 1.0650711601225653 0.9478942887658227 1.047383747753595 1.147369117721809 1.0407589255302225 1.0339114976287354 1.0 17.19449386391129 -7.001467783727267 24.999927083769403 1.064402174036998 1.031743991355001 0.035320194534096516 0.05344199419311564 161.15459415583663 2744900.496535346 0.01911791457599343 0.01665518798253748 9.966260078169439e-08 7.001467783727267 -0.03265818268199694 S(ph)MGGAAIAPPTSLVEK ddPTM_PC-9_AZD4547_30min_R2 1 SMGGAAIAPPTSLVEK 16 0 H0Y6J6;Q5W012;Q96I25;Q5W011;Q5W010 H0Y6J6 RBM17 Splicing factor 45 1 S(1)MGGAAIAPPTSLVEK 91.65700000000001 0.017882 0.0 9812.9 14841.0 29254.0 30799.0 33030.0 39036.0 21134.0 45169.0 26640.0 27161.0 True False 12933.198079000296 19638.063018427085 28866.07284577595 23698.766389806588 28444.35463930118 36595.07274907288 23014.88505801707 38189.168930361484 28048.136013362102 26210.10165716498 0.49344326276066863 0.7492555074870793 1.1013338758983757 0.9041844514680897 1.0852439647644565 1.3962201760125181 0.8780921706850975 1.4570400920181787 1.070126944955769 1.0 14.677835328790117 -4.657817346500784 0.8124877037029875 1.1619300809486202 1.6602797140196934e-11 0.5743135564093943 0.17628408243143323 2.050568926513221 0.9084008808290823 0.06337247646327095 2.256321791833717 2.19878443260404e-05 4.657817346500784 -1.1619300809320174 S(ph)MGGAAIAPPTSLVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SMGGAAIAPPTSLVEK 16 0 H0Y6J6;Q5W012;Q96I25;Q5W011;Q5W010 H0Y6J6 RBM17 Splicing factor 45 1 S(1)MGGAAIAPPTSLVEK 86.54799999999999 0.021929 0.0 12879.0 13517.0 22095.0 20287.0 26220.0 23062.0 18347.0 22171.0 21489.0 12085.0 True False 15059.160328155114 14858.878429259094 22621.828595754127 19150.38516134142 21082.379221844894 21852.588121669283 16609.03933922283 21589.03474211627 21803.2359718061 14275.914835192641 1.05486481966337 1.0408354631416927 1.584614986633805 1.341447142436879 1.4767795595048747 1.5307311912367823 1.1634308225402568 1.512269790857501 1.5272741693623226 1.0 13.801295579491743 -5.243265965255562 24.34195538866686 1.4083679059865433 1.04785000074581 0.37912239452621 0.17521004820297653 542.1608613252465 726180.5227022961 0.04169946941626925 0.10980635881901676 5.711287659355274e-06 5.243265965255562 -0.36051790524073324 S(ph)MGGAAIAPPTSLVEK ddPTM_PC-9_Lapatinib_30min_R1 1 SMGGAAIAPPTSLVEK 16 0 H0Y6J6;Q5W012;Q96I25;Q5W011;Q5W010 H0Y6J6 RBM17 Splicing factor 45 1 S(1)MGGAAIAPPTSLVEK 70.167 0.017811 5194100.0 15644.0 18712.0 20765.0 20080.0 20734.0 15221.0 16050.0 14986.0 16462.0 14364.0 True False 15420.913691241765 18668.67351366186 19057.781855218 21556.750184916342 19514.466884612393 14570.033311884006 16880.99046674686 15682.304269082719 14607.87620745493 16846.7982611731 0.9153616878515382 1.1081437092226387 1.1312405811340762 1.2795754926678438 1.1583487011646292 0.8648547389247033 1.0020295966654131 0.9308774299996103 0.8671010349261306 1.0 14.040186812402652 -6.754684092679571 24.999789540220114 0.9329684592757342 1.1276094846478535 0.49407690698532214 0.093661556306391 139.76003741799985 517219.82950175577 0.03284077436950353 0.032129961959626745 1.759202798910387e-07 6.754684092679571 0.19464102537211925 S(ph)MGNLLEK ddPTM_PC-9_AZD4547_30min_R2 2 SMGNLLEK 8 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 S(1)MGNLLEK;S(1)MGNLLEK 89.171 0.009180500000000001 33205000.0 161808.0 244677.0 250614.0 224924.0 247521.0 299309.0 298951.0 383590.0 293557.0 268423.0 True False 213259.5781845201 323764.0553304817 247290.69461172124 173071.24684115883 213156.9816734623 280593.1609143427 325557.0598551745 324314.97952129424 309073.82371150627 259025.59247160226 0.8233147008742018 1.2499307587375825 0.9546959906629012 0.6681627293647949 0.8229186144872203 1.0832642374714574 1.2568528721379773 1.25205766899983 1.1932173217416382 1.0 17.9827351217996 -6.962427751313831 4.968721702667286 1.1941869810775623 0.913942101189199 0.4104361425888603 0.1538949431378404 0.204078622350866 12.118771319571072 0.06028637711944422 0.05186499568207673 1.0903658691985019e-07 6.962427751313831 -0.2802448798883632 S(ph)MGNLLEK ddPTM_PC-9_Lapatinib_30min_R1 2 SMGNLLEK 8 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 S(1)MGNLLEK;S(1)MGNLLEK 85.92399999999999 0.012862 72564000.0 653936.0 879625.0 671185.0 548658.0 689306.0 554514.0 523734.0 620950.0 646980.0 434624.0 True False 644610.7527228243 877588.2823564971 616002.7601490243 589008.1395894333 648762.3763077386 530798.728855269 550850.3838698564 649801.6038894248 574110.2993985658 509748.1792999228 1.2645670527124175 1.7216114112693017 1.2084452385784472 1.1554884617702106 1.2727115125722175 1.0412959779165012 1.0806323715101493 1.2747502203575272 1.126262579666369 1.0 18.959425191722012 -5.427421721693972 7.1002538798446055 1.1493397864252048 1.4915220687543347 0.5299830668633102 0.1322157012684627 0.1816155596772132 11.680723236267776 0.03254859326024882 0.06814655981898277 3.7374748447768105e-06 5.427421721693972 0.34218228232912984 S(ph)MGSQEDDSGNKPSSYS ddPTM_PC-9_AZD4547_30min_R2 1 SMGSQEDDSGNKPSSYS 17 1 H7C3P9;Q9UNS2-2;Q9UNS2 H7C3P9 COPS3 COP9 signalosome complex subunit 3 1 S(0.5)MGS(0.5)QEDDSGNKPSSYS 74.428 0.020881999999999998 4309700.0 19164.0 16345.0 22222.0 25716.0 29251.0 22366.0 21807.0 25148.0 17786.0 21492.0 True False 25257.75336403731 21628.201606104078 21927.321760403127 19787.573508239428 25190.003559012977 20967.450484316127 23747.780754243322 21261.954443550476 18726.131649161343 20739.571621655683 1.2178531854372474 1.0428470751787617 1.0572697527420107 0.9540975035172758 1.2145864928429997 1.0109876359462748 1.145046830641697 1.0251877344153693 0.9029179575535706 1.0 14.340098474968883 -8.012001312227536 6.786055269085688 0.9546468227729742 1.0850907680425166 0.3162369917925326 0.08242831833763971 0.17996845928455227 41.19341313718011 0.0490843851157924 0.020501161928856596 9.727442846105301e-09 8.012001312227536 0.1304439452695424 S(ph)MGYDDLDYGMMSDYGTAR ddPTM_PC-9_AZD4547_30min_R2 6 SMGYDDLDYGMMSDYGTAR 19 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 S(0.72)MGY(0.27)DDLDY(0.008)GMMS(0.001)DYGTAR;S(0.89)MGY(0.099)DDLDY(0.01)GMMS(0.002)DYGTAR;S(0.988)MGY(0.012)DDLDYGMMSDYGTAR;S(0.527)MGY(0.453)DDLDY(0.02)GMMS(0.001)DYGTAR;S(0.574)MGY(0.425)DDLDYGMMSDYGTAR;S(0.749)MGY(0.235)DDLDY(0.011)GMMS(0.004)DYGTAR 92.427 0.00054915 175416800.0 122869.8 163757.0 163533.5 156638.2 178219.0 209093.0 185573.0 254065.0 200260.0 171570.0 True False 161939.84054939455 216688.2478073284 161364.9389391091 120527.68302606574 153476.36813386672 196018.38165595615 202088.63749746396 214805.09208289554 210845.33476110714 165563.3865218439 0.978113844802448 1.308793280685517 0.9746414489885971 0.7279851273769621 0.9269946173371946 1.1839476455145723 1.2206118861358337 1.2974190525787224 1.2735021866280132 1.0 17.337024138073573 -6.843917330087387 5.765136083897214 1.2189713571081808 0.9871862664741553 0.3215128407151284 0.152328799147535 0.26301443984909884 14.137001983115256 0.05868038375860753 0.05196047657769766 1.4324605486462727e-07 6.843917330087387 -0.23178509063402553 S(ph)MGYDDLDYGMMSDYGTAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SMGYDDLDYGMMSDYGTAR 19 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 S(0.999)MGY(0.001)DDLDYGMMSDYGTAR;S(0.817)MGY(0.139)DDLDY(0.017)GMMS(0.026)DY(0.001)GTAR;S(0.906)MGY(0.09)DDLDY(0.004)GMMSDYGTAR;S(0.988)MGY(0.012)DDLDYGMMSDYGTAR;S(0.995)MGY(0.004)DDLDYGMMSDYGTAR;S(0.989)MGY(0.011)DDLDYGMMSDYGTAR 86.22200000000001 0.00077992 119324600.0 135352.1 163253.0 192283.0 154059.0 221833.0 134256.0 168294.0 113541.0 134871.4 140184.7 True False 158264.53720416853 179459.6789385094 196867.75595733788 145427.573696017 178366.4160915149 127215.37901581942 152351.97397695348 110560.66905663385 136843.63907337957 165599.07640852555 0.9557090573001564 1.0836997574539025 1.1888215817802865 0.8781907293809638 1.0770978918474936 0.768213094993264 0.9200049739474871 0.667640614032687 0.8263550862795418 1.0 17.3373351009905 -6.759118378512192 24.99193794721048 0.8208929183875228 1.0389594151893327 0.438340768486596 0.1126436681802317 53.74756742228995 578741.0994179575 0.03718896995615738 0.03551836215902543 1.741332162301061e-07 6.759118378512192 0.2180664968018099 S(ph)MGYDDLDYGMMSDYGTAR ddPTM_PC-9_Lapatinib_30min_R1 11 SMGYDDLDYGMMSDYGTAR 19 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 S(0.615)MGY(0.38)DDLDY(0.004)GMMSDYGTAR;S(0.882)MGY(0.117)DDLDYGMMSDYGTAR;S(0.996)MGY(0.003)DDLDYGMMSDYGTAR;S(0.999)MGY(0.001)DDLDYGMMSDYGTAR;S(0.952)MGY(0.046)DDLDY(0.001)GMMSDYGTAR;S(0.831)MGY(0.04)DDLDY(0.113)GMMS(0.015)DYGTAR;S(0.984)MGY(0.006)DDLDY(0.009)GMMSDYGTAR;S(0.804)MGY(0.151)DDLDY(0.025)GMMS(0.019)DYGTAR;S(0.812)MGY(0.188)DDLDYGMMSDYGTAR;S(0.959)MGY(0.001)DDLDY(0.029)GMMS(0.01)DYGTAR;S(0.841)MGY(0.159)DDLDYGMMSDYGTAR 113.14 5.6478000000000004e-05 132166500.0 312872.6 333469.0 279786.8 242566.6 304197.9 253660.40000000002 241769.0 240832.3 309035.0 229917.8 True False 308410.97935019276 332696.87301877356 256783.80931228108 260405.75694245662 286305.5775980822 242811.93600327292 254286.61583519776 252022.24785953568 274228.22401718097 269658.78538378817 1.1437082567558519 1.2337698270993371 0.9522545647708717 0.9656861599070014 1.0617328012903482 0.9004414065638328 0.9429939969257365 0.9345968368909193 1.0169452614973749 1.0 18.040775511523385 -5.265949618250702 24.999809671623147 0.9689072907028877 1.188739049928136 0.7676014339908858 0.04771844648702513 149.85039586343322 830609.916106374 0.01235792073925163 0.02720346635457992 5.42063770631732e-06 5.265949618250702 0.21983175922524834 S(ph)MIPHLES(ph)GMKS(ph)SK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SMIPHLESGMKSSK 14 1 Q08116-2;Q08116 Q08116-2 RGS1 Regulator of G-protein signaling 1 3 S(1)MIPHLES(0.972)GMKS(0.837)S(0.192)K 40.725 0.040091 3940600.0 20271.0 17469.0 20648.0 27985.0 36203.0 27519.0 27745.0 22439.0 22980.0 21222.0 True False 23702.47992950013 19203.206871400984 21140.326627976057 26417.09117859413 29109.282035410008 26075.855195569213 25116.792743595026 21850.00002608574 23316.039026111204 25069.380606740426 0.9454752912055283 0.7660024462765467 0.8432727939952389 1.0537592289572302 1.1611488329944366 1.0401475650562413 1.001891236867729 0.8715811678335169 0.9300604347537091 1.0 14.613638731260872 -5.752120015599914 24.825071813938926 1.0104389244671093 0.8430253319878405 0.43098377901482876 0.08235625735003252 181.7687281941647 484193.0416186225 0.02508255985374303 0.04269866116475476 1.7696198631377239e-06 5.752120015599914 -0.1674135924792688 S(ph)MIVHSEGQLR ddPTM_PC-9_AZD4547_30min_R2 1 SMIVHSEGQLR 11 0 A8MTI9 A8MTI9 PRSS47 Putative serine protease 47 1 S(0.999)MIVHS(0.001)EGQLR 76.1 0.018483000000000003 5800700.0 8178.9 7770.3 15382.0 23479.0 16665.0 17394.0 15767.0 22804.0 15152.0 12742.0 True False 10779.620068311666 10281.897518501713 15178.02462957974 18066.279296933935 14351.352408839055 16306.350430304694 17170.232455273723 19280.165783788958 15952.903786578918 12295.906458362952 0.8766836430330847 0.8362049234286889 1.2343965596173303 1.4692921874536802 1.167165060781518 1.3261609044865557 1.396418597800534 1.5680150015028558 1.2974158384011365 1.0 13.585890474367966 -5.337687308186416 3.872476604999995 1.3393527014337336 0.8515685062566097 0.5944630281866907 0.14909314726801648 0.1358372802746953 3.871560280495388 0.038802236156678736 0.09094111552390406 4.595287542330223e-06 5.337687308186416 -0.4877841951771239 S(ph)MPVLGSVSSVTK ddPTM_PC-9_AZD4547_30min_R2 6 SMPVLGSVSSVTK 13 0 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 S(1)MPVLGSVSSVTK;S(1)MPVLGSVSSVTK;S(1)MPVLGSVSSVTK;S(1)MPVLGSVSSVTK;S(0.999)MPVLGS(0.001)VSSVTK;S(1)MPVLGSVSSVTK 139.86 7.0265e-05 148050000.0 295603.0 374881.0 594258.0 731885.0 656609.0 546078.0 629973.0 713944.0 615711.0 636578.0 True False 389598.60507563833 496053.95205248694 586377.7506387206 563160.2207605314 565450.1742463481 511931.65633436345 686039.3765805896 603620.3596010085 648256.22646108 614291.5979792629 0.6342242126658393 0.8075219548570687 0.9545592884025013 0.9167636715414466 0.9204914670922072 0.8333691328652115 1.116797590651319 0.9826283829807245 1.0552907260876514 1.0 19.228564125300835 -3.995752103380221 0.5720427147193301 1.000709533786529 1.600979152214539e-38 0.7050756158258424 0.07087782099370901 5.227340729637372 0.6657642321850248 0.037183484264015895 4.227644589251784 0.00010098291351604147 3.995752103380221 -1.000709533786529 S(ph)MPVLGSVSSVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SMPVLGSVSSVTK 13 0 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 S(0.999)MPVLGSVSSVTK;S(0.999)MPVLGSVSSVTK;S(1)MPVLGSVSSVTK;S(1)MPVLGSVSSVTK;S(1)MPVLGSVSSVTK;S(0.999)MPVLGS(0.001)VSSVTK 85.287 0.0081664 121214700.0 142692.0 160211.0 204420.0 256679.0 292557.0 267727.0 275146.0 269674.0 246317.0 218921.0 True False 166846.9373045352 176115.68928238732 209294.1480671673 242298.10779454556 235232.55598799657 253686.92481355285 249082.17899546566 262595.34324322146 249918.920139018 258609.64432231727 0.6451690451906971 0.6810097502121233 0.8093052701712633 0.9369260316237786 0.9096047311167377 0.9809646715934963 0.9631588939700289 1.0154120273872564 0.9663944312437645 1.0 17.98041655297451 -5.413297940570655 0.982299671614216 0.9832038462737182 0.5878859128744509 0.9641766175482265 0.023941199081895573 0.1431342836815719 0.20754249613076522 0.008622194721846646 0.04856095800711005 3.8610200725757985e-06 5.413297940570655 -0.39531793339926724 S(ph)MPVLGSVSSVTK ddPTM_PC-9_Lapatinib_30min_R1 6 SMPVLGSVSSVTK 13 0 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 S(1)MPVLGSVSSVTK;S(1)MPVLGSVSSVTK;S(1)MPVLGSVSSVTK;S(0.994)MPVLGS(0.005)VS(0.001)SVTK;S(0.998)MPVLGS(0.002)VSSVTK;S(1)MPVLGSVSSVTK 123.76 0.00016201 126518600.0 435530.0 411893.0 415598.0 332780.0 387249.0 379131.0 354077.0 338905.0 375826.0 295282.0 True False 429319.26233357925 410939.28706513054 381429.1366946734 357253.7513215369 364471.7751808271 362916.45092752716 372409.37454793334 354651.76353353035 333496.51825677045 346321.1002614677 1.2396566712494534 1.1865846081999538 1.1013742345086672 1.0315679612123407 1.0524099597329066 1.0479189707284084 1.075329728008976 1.0240547378307967 0.9629691000778906 1.0 18.40175076354636 -1.5228787509996715 0.4051821129956242 1.00928671736627 5.203889243197201 0.8775949770332497 0.0280068226467752 25.64948166407371 0.33737593022425383 0.02156707430279168 86.23545071195004 0.02999999960492241 1.5228787509996715 4.194602525830931 S(ph)MSAAFCSLLAPER ddPTM_PC-9_AZD4547_30min_R2 2 SMSAAFCSLLAPER 14 0 E9PNR2;Q13671-2;Q13671 E9PNR2 RIN1 Ras and Rab interactor 1 1 S(0.869)MS(0.131)AAFCSLLAPER;S(0.989)MS(0.011)AAFCSLLAPER 188.63 3.4675e-06 82965600.0 40992.0 36878.0 52438.0 74416.0 57245.0 60023.0 55972.0 62346.0 47493.0 56741.0 True False 54026.603313432344 48798.0923114045 51742.637857619484 57260.54091573906 49297.5198706266 56269.752321385444 60953.399567868386 52711.85826855402 50003.38302111882 54754.514860616284 0.9867059081970333 0.8912158647670513 0.9449930839372083 1.0457683911820266 0.9003370771546224 1.0276732880316146 1.113212302639007 0.9626942801472704 0.9132284917217877 1.0 15.740690308618902 -6.788850443597986 24.999737828452336 1.0078957357292007 0.9549465248669057 0.1340696244926355 0.062410154713114376 467.8540465810643 426693.9360731553 0.023083854535863438 0.02036257807694476 1.6261086364254803e-07 6.788850443597986 -0.05294921086229498 S(ph)MSAAFCSLLAPER ddPTM_PC-9_Lapatinib_30min_R1 1 SMSAAFCSLLAPER 14 0 E9PNR2;Q13671-2;Q13671 E9PNR2 RIN1 Ras and Rab interactor 1 1 S(0.561)MS(0.439)AAFCSLLAPER 71.529 0.021913 26339000.0 69069.0 46052.0 65352.0 53101.0 56275.0 52833.0 38304.0 38657.0 56905.0 35411.0 True False 68084.0633942966 45945.36942342645 59979.010826015234 57006.2246797432 52965.01514090689 50573.455749738365 40287.19369708861 40453.14534431673 50495.75966378464 41531.74416780841 1.6393258881496509 1.1062711269188419 1.4441726931493875 1.3725940439537136 1.275289930682962 1.2177060405986575 0.9700337538030859 0.9740295322263949 1.21583527674054 1.0 15.341926840028979 -6.88977684876995 1.9723138223252512 1.039026729541974 1.3685192824920756 0.5481645181303939 0.1404770814963532 0.257329121891848 2.0462002150115697 0.05722765223621447 0.047977145892181314 1.2889116562154034e-07 6.88977684876995 0.3294925529501016 S(ph)MSAPGNLLVK ddPTM_PC-9_AZD4547_30min_R2 1 SMSAPGNLLVK 11 0 J3KPJ3;Q8N5S9 J3KPJ3 CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 1 S(0.912)MS(0.088)APGNLLVK 80.23100000000001 0.01444 5706300.0 52591.0 41199.0 48306.0 52546.0 46404.0 39198.0 39917.0 47776.0 43886.0 50638.0 True False 69313.84403924466 54515.77105964401 47665.430877420295 40432.33152760729 39961.60559134522 36746.94286346343 43469.5356705246 40393.31698326177 46205.72436495528 48865.179033007626 1.4184710955919 1.115636372125425 0.9754477896258823 0.8274262435485177 0.8177930866548512 0.7520067170661848 0.8895810172139479 0.826627831568503 0.9455756692049377 1.0 15.576519156975143 -4.805615560703919 1.2906647576153232 0.8529991502758337 1.6496434872950525 0.8571115779777991 0.06971857444685532 0.43999191111574304 0.6598837698089216 0.0205270811640979 0.4622567865666369 1.564531960098844e-05 4.805615560703919 0.7966443370192188 S(ph)MSAPGNLLVK ddPTM_PC-9_Lapatinib_30min_R1 1 SMSAPGNLLVK 11 0 J3KPJ3;Q8N5S9 J3KPJ3 CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 1 S(0.995)MS(0.005)APGNLLVK 137.95 9.6448e-05 6093500.0 69257.0 51746.0 61831.0 42679.0 51562.0 39141.0 31970.0 30979.0 44123.0 44600.0 True False 68269.38247982183 51626.18531626475 56747.49385456218 45817.75603297035 48529.22453479235 37467.03067212745 33625.2501695886 32418.39743439966 39153.403104211786 52309.05057423559 1.3051160694063022 0.9869455619921502 1.0848503888256904 0.8759049443642076 0.9277404961866206 0.7162628696339126 0.642818973016315 0.6197473874696378 0.7485015054640752 1.0 15.674772964433023 -5.613811212750162 0.7286730544384226 0.7168953684552137 1.2739938118402276 0.632384520588098 0.12392311520561525 0.716881270527637 0.5939681300400216 0.05951447739804923 0.2764547966282053 2.433261514843811e-06 5.613811212750162 0.5570984433850139 S(ph)MSDVSAEDVQNLR ddPTM_PC-9_AZD4547_30min_R2 4 SMSDVSAEDVQNLR 14 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;E9PJ10;E9PK58;E9PLU6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(1)MSDVSAEDVQNLR;S(0.982)MS(0.018)DVSAEDVQNLR;S(0.556)MS(0.444)DVSAEDVQNLR;S(0.933)MS(0.067)DVSAEDVQNLR 165.51 3.0766000000000003e-06 20738500.0 49171.1 54383.2 72394.0 85374.0 80362.0 80711.0 79654.0 89747.0 82594.0 80110.0 True False 64806.48697758377 71961.50587856099 71434.00825860079 65692.34331515139 69205.12344909256 75664.1284109647 86743.05168975523 75878.66333089398 86959.7502210071 77305.37328358636 0.8383180136760767 0.9308732733826667 0.9240497163962057 0.8497771956182938 0.8952175057123272 0.978769329958463 1.1220830843355192 0.9815444917721482 1.124886234000898 1.0 16.238281074943643 -6.939595357176279 3.433399877447154 1.0558737799830609 0.8900522948168653 0.7153693791654254 0.0503199400051835 0.12593510335927607 3.026737018364341 0.018081853927643915 0.01536757919452802 1.1492238829116851e-07 6.939595357176279 -0.16582148516619555 S(ph)MSDVSAEDVQNLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SMSDVSAEDVQNLR 14 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;E9PJ10;E9PK58;E9PLU6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.992)MS(0.008)DVSAEDVQNLR;S(0.77)MS(0.23)DVSAEDVQNLR 136.33 1.538e-05 9319000.0 15942.900000000001 22853.0 23287.5 25773.0 32303.0 28084.0 21796.0 19793.5 25411.0 22434.8 True False 18641.7180833717 25121.69480978456 23842.762318335546 24329.02236719337 25973.459039025754 26611.225600943555 19731.325090625236 19273.941597946792 25782.587802111062 26502.05164622091 0.7034066015802191 0.9479150952211964 0.8996572279239156 0.9180052432152964 0.9800546533433939 1.0041194529457576 0.7445206640610726 0.7272622457776843 0.9728525227512927 1.0 14.693816429234941 -12.62242755533309 1.1391887361629423 3.149613426152657 0.8798443053711436 0.10611662630555563 0.10646071627437552 265817.34769241855 5148.774026303319 1470859.3405536523 0.03224971691023931 2.385461681165639e-13 12.62242755533309 -2.269769120781514 S(ph)MSDVSAEDVQNLR ddPTM_PC-9_Lapatinib_30min_R1 4 SMSDVSAEDVQNLR 14 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;E9PJ10;E9PK58;E9PLU6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(1)MSDVSAEDVQNLR;S(0.804)MS(0.196)DVSAEDVQNLR;S(0.999)MS(0.001)DVSAEDVQNLR;S(0.991)MS(0.009)DVSAEDVQNLR 189.33 2.9442e-06 16558200.0 58687.4 60829.8 68638.0 58868.1 64900.0 71871.0 65788.0 71450.0 73221.0 61575.0 True False 57850.506914048914 60688.95233547181 62994.84859034212 63197.45645222479 61082.70959830926 68797.24486948394 69194.18073684383 74769.82784104889 64974.07992868778 72218.15670646998 0.8010521114403648 0.8403558759072388 0.8722854675782448 0.8750909651306978 0.8458082064677912 0.9526308619189728 0.9581272064043802 1.0353328200406742 0.8996917519339952 1.0 16.14007397701168 -6.8240769913592505 3.5604943418089974 0.9742200756919771 0.8486268611581601 0.7290801196270222 0.03734969969073774 0.1250417712236072 3.1919247809027422 0.013472717667760535 0.012103245974274991 1.4994189962048997e-07 6.8240769913592505 -0.125593214533817 S(ph)MSENAVR ddPTM_PC-9_Lapatinib_30min_R1 2 SMSENAVR 8 0 Q9GZY8-5;C9JHF5;H7C433;A0A0A0MS29;Q9GZY8-4;Q9GZY8-3;Q9GZY8-2;Q9GZY8 Q9GZY8-5 MFF Mitochondrial fission factor 1 S(0.753)MS(0.247)ENAVR;S(0.907)MS(0.093)ENAVR 97.59700000000001 0.0057644 28477000.0 56093.0 64715.0 50109.0 40651.0 40976.0 41649.0 33840.0 35984.5 61302.0 25203.0 True False 55293.103533803645 64565.15639357778 45989.23144633364 43640.61014776067 38565.87224191558 39867.769358560974 35592.06961960832 37656.4712378758 54397.52322132201 29559.304969113444 1.8705819907328498 2.1842582720074777 1.5558292556062412 1.476374704796368 1.304694825612886 1.3487383888159366 1.204090206342758 1.27392952159136 1.84028424478052 1.0 14.851324727199897 -5.465137940687582 2.7720998144272433 1.3529062407362098 2.0291346011538245 0.6008824960071484 0.21649637729466237 0.17491693485179408 2.6225968494066567 0.05825715305546181 0.13728697521065375 3.4265893387131094e-06 5.465137940687582 0.6762283604176147 S(ph)MSIDDTPR ddPTM_PC-9_AZD4547_30min_R2 2 SMSIDDTPR 9 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GUE9;Q96N67-7;A0A0C4DGY6;A0A1B0GVW2 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 S(0.999)MS(0.001)IDDTPR;S(0.999)MS(0.001)IDDTPR 154.84 2.089e-12 3646400.0 41985.0 42278.0 41740.0 70489.0 64037.0 59594.0 44458.0 57202.0 38272.0 50780.0 True False 55335.35665774924 55943.53670864901 41186.5003275685 54238.850094193884 55146.567909080506 55867.577759203064 48414.675873441985 48362.74527119349 40294.979786163436 49002.20765622905 1.1292421159052644 1.1416533944983924 0.8405029548160156 1.106865439098215 1.125389457878239 1.1401032816957442 0.9880100956489788 0.9869503351864949 0.8223094777453609 1.0 15.580559126796633 -7.685787650598576 2.301317384319602 0.9175146993377493 1.074540196017694 0.31885200696547567 0.09516965552499748 0.382443276434586 4.048302614994525 0.06183209806775789 0.028418847981334865 2.0616377099164326e-08 7.685787650598576 0.1570254966799446 S(ph)MSIDDTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SMSIDDTPR 9 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GUE9;Q96N67-7;A0A0C4DGY6;A0A1B0GVW2 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 S(0.79)MS(0.21)IDDTPR 109.79 0.0021274 0.0 119840.0 119500.0 162730.0 166380.0 143580.0 176660.0 162200.0 134460.0 162210.0 122170.0 True False 140126.54505210856 131363.1702520134 166610.1003569617 157058.26801123781 115446.52969765392 167395.63860784384 146835.24177369304 130930.56747214623 164582.0143788293 144318.45390281238 0.970953757213012 0.9102312746537363 1.1544615109940206 1.088275710859574 0.7999429496064202 1.159904600423257 1.0174391271720213 0.9072337177359044 1.1404086582694608 1.0 17.138896262497695 -8.277352103601652 24.88691651140016 1.0702042883238239 1.0051860978085223 0.05668648101746376 0.1118212766518064 3124.4220234186255 4886435.238220809 0.1047020557587348 0.027348941701607864 5.280169892077474e-09 8.277352103601652 -0.06501819051530155 S(ph)MSIDDTPR ddPTM_PC-9_Lapatinib_30min_R1 2 SMSIDDTPR 9 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GUE9;Q96N67-7;A0A0C4DGY6;A0A1B0GVW2 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 S(0.998)MS(0.002)IDDTPR;S(1)MSIDDTPR 130.98 0.0012483 22779000.0 79238.0 70334.0 62032.0 56310.0 64759.0 56112.0 61565.0 56937.0 65871.0 51935.0 True False 78108.0515895304 70171.14594430814 56931.968410444635 60451.22524465341 60950.0029410926 53712.22056346064 64752.53446014149 59582.5008787376 58451.91432761903 60911.89555096242 1.2823119504494926 1.152010544239243 0.9346609212450473 0.9924371044088821 1.0006256149112662 0.8818018233978926 1.0630523623413717 0.9781751222778386 0.9596141081952502 1.0 15.894436380694424 -5.036246101972428 3.0123943659362706 0.9768336168653359 1.276620278041033 0.8263337372777104 0.04587857347493584 0.09953328439936261 1.7075104074136953 0.011802230132455373 0.05328133748153743 9.199281276770948e-06 5.036246101972428 0.2997866611756971 S(ph)MSLIPTSPQVPGEWPSPEELGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SMSLIPTSPQVPGEWPSPEELGAR 24 0 M0QZ22;Q5PRF9;A0A087WZT0;M0R0X3 M0QZ22 SAMD4B Protein Smaug homolog 2 1 S(0.5)MS(0.5)LIPTSPQVPGEWPSPEELGAR;S(0.48)MS(0.48)LIPT(0.031)S(0.009)PQVPGEWPSPEELGAR 74.14399999999999 0.00021713 3150800.0 37720.0 31204.7 27403.0 31688.0 37925.0 30201.0 33607.0 34813.0 29197.0 28519.0 True False 44105.2509960409 34302.496391322136 28056.391446456222 29912.624093882107 30493.86849689045 28617.20639417803 30423.501666390246 33899.19563742249 29623.950889702763 33689.26894372023 1.3091780373661757 1.0182024563556527 0.8327990581608038 0.8878976906222805 0.9051507929077396 0.8494457520578628 0.9030620912912766 1.0062312629595185 0.8793289916498692 1.0 15.040001501903072 -4.811902093539595 2.9803980221497577 0.9054504922315029 1.3612877070239915 0.8332923947187767 0.05407477882683081 0.13069047967398706 1.754072779552023 0.013805957225882402 0.1393661333208528 1.5420480499281065e-05 4.811902093539595 0.4558372147924886 S(ph)MSSADVEVAR ddPTM_PC-9_AZD4547_30min_R2 1 SMSSADVEVAR 11 0 I3L4C2;Q9UQB8-5 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 S(0.997)MS(0.003)SADVEVAR 105.25 0.0022732 9801100.0 26609.0 35388.0 34183.0 52119.0 40990.0 45293.0 43337.0 55132.0 42825.0 46477.0 True False 35070.10849841729 46826.478949942546 33729.71108522459 40103.76978052306 35299.246038902675 42460.82154994768 47193.909045106695 46612.61620732561 45088.6420710297 44849.85437649779 0.7819447573679241 1.0440720399413503 0.7520584303814289 0.8941783722164821 0.7870537492179724 0.9467326514263554 1.0522644878382759 1.0393036244004294 1.0053241576333198 1.0 15.452815680398656 -6.999859089880373 5.02855212245886 1.0250220233737688 0.8592385637092372 0.5228169972192004 0.07755928470372898 0.14693312302547032 10.93000934719224 0.02770908088542282 0.02301221068720089 1.0003245101829459e-07 6.999859089880373 -0.16578345966453156 S(ph)MSSADVEVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SMSSADVEVAR 11 0 I3L4C2;Q9UQB8-5 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 S(0.742)MS(0.208)S(0.051)ADVEVAR 97.779 0.0046224 12459000.0 49041.0 43570.0 61224.0 62174.0 48620.0 53871.0 48651.0 34232.0 40436.0 26272.0 True False 57342.67269609867 47895.34165590134 62683.812353313006 58690.59235082766 39093.26002159035 51045.90992552452 44042.42507726222 33333.4462718021 41027.300002603704 31034.90563096244 1.847683166108612 1.5432733137785937 2.0197842100339933 1.8911155409563776 1.2596545478968164 1.6447902414305329 1.4191254712024204 1.0740630781408431 1.3219727648107362 1.0 14.921604138616603 -7.209545858236895 0.6034792327121556 1.0480818057448738 1.830625071733281 0.6574884697989546 0.19359523469001114 0.5140826893728881 0.3852228625476895 0.17641411063237858 0.1357673803270453 6.172401125254637e-08 7.209545858236895 0.7825432659884073 S(ph)MSSADVEVAR ddPTM_PC-9_Lapatinib_30min_R1 4 SMSSADVEVAR 11 0 I3L4C2;Q9UQB8-5 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 S(1)MSSADVEVAR;S(0.945)MS(0.052)S(0.003)ADVEVAR;S(1)MSSADVEVAR;S(0.996)MS(0.003)S(0.001)ADVEVAR 115.29 0.0012102 24253700.0 117220.0 134913.0 131211.0 132712.0 146361.0 150416.0 123318.0 131555.0 132235.0 117509.0 True False 115548.42130448499 134600.61723752972 120423.33806910699 142472.08319425388 137752.3337367974 143983.05831682158 129702.80264039183 137667.52556513887 117341.30180371791 137820.27407909988 0.8383992999329526 0.9766387284956183 0.873770850288629 1.033752719955296 0.9995070366623745 1.0447160933244457 0.9411010354394655 0.9988916832811308 0.8514081298109423 1.0 17.072428606034222 -3.7466068427052135 1.052778828893545 0.9764182307295459 9.360938294466597e-19 0.28252767151558233 0.060941507430715185 17.47702102565443 2.9759786786391227 0.018678262614802838 31.76466470899019 0.00017922275842952685 3.7466068427052135 -0.9764182307295459 S(ph)MT(ph)DVLT(ph)MLRRHVTDGLLK ddPTM_PC-9_AZD4547_30min_R2 1 SMTDVLTMLRRHVTDGLLK 19 2 Q5T5P2;Q5T5P2-2;Q5T5P2-7;Q5T5P2-10;Q5T5P2-3;Q5T5P1;Q5T5P2-4;Q5T5P2-8;Q5T5P2-6;Q5T5P0;Q5T5P2-9 Q5T5P2;Q5T5P2-9 KIAA1217 Sickle tail protein homolog 3 S(0.999)MT(0.996)DVLT(0.965)MLRRHVT(0.04)DGLLK 40.493 0.045915 0.0 8418.3 7638.0 10403.0 14500.0 9100.3 13185.0 10547.0 11531.0 7616.8 7757.8 True False 11095.144288482328 10106.834130769217 10265.049422800545 11157.249022766828 7836.880427612248 12360.539865675939 11485.662567753667 9749.148906019582 8019.408497994612 7486.201783290541 1.4820792452117801 1.350061676580508 1.3711959308540795 1.4903751389216078 1.0468433331712264 1.6511096312238187 1.534244320449665 1.302282410792081 1.0712252661816044 1.0 12.870018219866198 -8.217050414352412 2.929611939185064 1.0118040630633285 1.4112542347045045 0.5038732639362502 0.14984647514111288 0.22211783715671193 3.518742799614379 0.1326570803899148 0.039561122802387806 6.066659016989208e-09 8.217050414352412 0.399450171641176 S(ph)NATNSSYSPTTGR ddPTM_PC-9_AZD4547_30min_R2 1 SNATNSSYSPTTGR 14 0 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 S(0.874)NAT(0.022)NS(0.007)S(0.027)YS(0.034)PT(0.034)T(0.003)GR 107.93 0.00073407 6804500.0 7899.9 9957.2 10086.0 15533.0 14179.0 11962.0 9102.0 14210.0 8046.4 11311.0 True False 10411.903871872179 13175.670176341357 9952.253049924671 11952.106832457725 12210.490597355478 11214.014249011421 9912.060367089582 12014.17101331525 8471.71627694883 10915.005332800456 0.9539073554626293 1.2071153219455995 0.9117955279432949 1.0950161239537552 1.1186884683108662 1.0273942986827884 0.9081131950804509 1.100702257763605 0.7761531963242062 1.0 13.414025214743283 -7.060040729339768 6.2368939726819415 0.9555885116242738 1.0609731767927901 0.1891595242144678 0.10819867078193197 0.39619300103425714 31.885110213327927 0.0388923175846115 0.03035139376880426 8.708819124075585e-08 7.060040729339768 0.1053846651685163 S(ph)NEDSLILEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNEDSLILEK 10 0 A0A0U1RRH6;O94880 A0A0U1RRH6 PHF14 PHD finger protein 14 1 S(0.999)NEDS(0.001)LILEK 102.33 0.010139 0.0 11347.0 17103.0 11961.0 14555.0 15632.0 12328.0 12946.0 8745.5 11349.0 10688.0 True False 13267.822986534362 18800.872810210716 12246.195602345097 13739.530537946683 12569.021815250922 11681.497977796333 11719.661159076624 8515.939891623193 11514.957654801397 12625.64979383855 1.0508625855446427 1.489101402082746 0.9699457693117205 1.0882236369847451 0.9955148464029739 0.9252195466008433 0.9282422172675773 0.6744951769356903 0.9120289127947157 1.0 13.62407001931285 -6.012348272449952 0.8264803162297342 0.855908595636658 1.2630252001428273 0.44267449087823585 0.14453539188662595 0.6001767382245491 0.8244659852459956 0.0683767105611552 0.16032399000515413 9.719674642580385e-07 6.012348272449952 0.40711660450616927 S(ph)NEVFATFK ddPTM_PC-9_AZD4547_30min_R2 1 SNEVFATFK 9 0 Q8N3L3 Q8N3L3 TXLNB Beta-taxilin 1 S(1)NEVFATFK 70.977 0.03622 2595900.0 1704.5 620.98 30504.0 79481.0 35887.0 14275.0 6617.6 36346.0 6783.0 12991.0 True False 2246.4955441975385 821.6996410742435 30099.497029040464 61157.88341920893 30904.709504710918 13382.381993365492 7206.553580010112 30729.56084799131 7141.53553223105 12536.189044152661 0.17920083498145606 0.06554620691983856 2.401008545980724 4.878506793716166 2.4652395872353257 1.067500015055016 0.5748599956995314 2.451268143752563 0.5696735672283216 1.0 13.61381122029622 -6.772543596574314 24.787445601360897 1.1885019017749552 2.0729759793839477 0.0914795103159145 1.347326860339332 582.7354646833488 1300805.8107834363 0.5322002003311018 0.4737463708078232 1.6883263686375427e-07 6.772543596574314 0.8844740776089925 S(ph)NFSNSADDIK ddPTM_PC-9_AZD4547_30min_R2 2 SNFSNSADDIK 11 0 P45973 P45973 CBX5 Chromobox protein homolog 5 1 S(1)NFSNSADDIK;S(0.966)NFS(0.034)NSADDIK 165.49 0.0013220999999999999 36279000.0 28425.0 33171.0 50905.0 61489.0 79253.0 85499.0 69507.0 80341.0 62795.0 83857.0 True False 37463.558723270726 43892.877055740515 50229.96643926389 47313.66104557994 68250.08895635894 80152.73401406355 75692.98834709894 67926.14450251659 66114.2155014667 80921.1919540841 0.4629635058332817 0.5424151077834591 0.6207269718390347 0.5846881379654716 0.8434142813304711 0.9905036255464874 0.935391416256551 0.8394110722078698 0.8170197930225853 1.0 16.304229950231374 -6.279340319981038 2.9324169742885493 0.9094908037640224 0.5478356583506849 0.8784718927910529 0.06461791476181518 0.09479965029962369 1.6456269205512914 0.022356048469443397 0.027602751725970223 5.256052324535221e-07 6.279340319981038 -0.36165514541333743 S(ph)NFSNSADDIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNFSNSADDIK 11 0 P45973 P45973 CBX5 Chromobox protein homolog 5 1 S(1)NFSNSADDIK;S(0.999)NFS(0.001)NSADDIK 164.7 0.00060487 22604000.0 28769.1 54356.0 72419.0 73792.0 108556.0 92677.0 113250.0 56966.0 63420.0 68350.0 True False 33639.14041437434 59752.10445371065 74145.74361058703 69657.67347689193 87285.23107576638 87816.85497146577 102522.14014100346 55470.70286046618 64347.397521147686 80741.31394169778 0.41662859782867434 0.7400437463385454 0.918312323529026 0.862726528418782 1.081047939581388 1.0876322254908701 1.2697606112161282 0.6870175892916585 0.7969575224848592 1.0 16.301019444219584 -4.625140272324357 1.1798522789950268 0.9804463949174034 3.738360060372153e-18 0.5529362526240964 0.15388454337141713 1.734285017255767 1.616689888311111 0.05097318076917377 2.2876350713937175 2.3706079018072758e-05 4.625140272324357 -0.9804463949174034 S(ph)NFSNSADDIK ddPTM_PC-9_Lapatinib_30min_R1 1 SNFSNSADDIK 11 0 P45973 P45973 CBX5 Chromobox protein homolog 5 1 S(1)NFSNSADDIK 141.85 0.00013519 23437000.0 59478.0 59143.0 53790.0 59492.0 48003.0 45205.0 42921.0 34338.0 52989.0 32484.0 True False 58629.83281307065 59006.05801723509 49367.59383540456 63867.240139494235 45179.557917529164 43271.68752800183 45143.23936593407 35933.468837032044 47020.82082109279 38098.81611779076 1.5388885741699636 1.548763558290238 1.295777634737361 1.6763576049721545 1.1858520164470925 1.1357751220987553 1.184898744002017 0.9431649720016476 1.234180628492962 1.0 15.217458547674113 -6.410456702692683 5.290899821484104 1.1071050924495611 1.5002702757348616 0.7373107779667305 0.11787729011173678 0.11788227606547244 4.726006849438644 0.03561920177730122 0.040312083033242185 3.8863624139858235e-07 6.410456702692683 0.3931651832853005 S(ph)NGDLSPK ddPTM_PC-9_AZD4547_30min_R2 3 SNGDLSPK 8 0 P49006 P49006 MARCKSL1 MARCKS-related protein 1 S(1)NGDLSPK;S(1)NGDLSPK;S(1)NGDLSPK 96.756 0.0060224 102668000.0 230549.0 353580.0 430000.0 348529.0 473330.0 543010.0 570700.0 608260.0 579900.0 485660.0 True False 303858.7862828973 467867.82036624505 424297.91904299095 268181.023769372 407616.2997705253 509055.4988593613 621491.1944076067 514267.3934242893 610552.330110686 468657.19122339867 0.6483604476220539 0.9983156753551716 0.9053481456998221 0.5722328149266273 0.8697536438232599 1.0862001232297438 1.3261104407365327 1.0973210334868184 1.3027695755972066 1.0 18.838173494493113 -6.798483176937101 3.303309811256301 1.190529986808967 0.7976428772853921 0.6251790944963365 0.14275937306847553 0.1594101878962458 3.58332260720955 0.05177686540843551 0.04716341999268166 1.590438290695925e-07 6.798483176937101 -0.39288710952357486 S(ph)NGDLSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SNGDLSPK 8 0 P49006 P49006 MARCKSL1 MARCKS-related protein 1 S(1)NGDLSPK;S(1)NGDLSPK;S(1)NGDLSPK;S(1)NGDLSPK 111.52 0.0037446 111407000.0 457483.0 843178.0 763130.0 744190.0 1020740.0 702649.0 972260.0 593338.0 663630.0 712148.0 True False 534925.8361988815 926883.1394707258 781325.9133866397 702495.4469965335 820733.3244434015 665800.849497129 880160.4942471667 577763.5061935764 673334.333285386 841254.795039533 0.6358666118197207 1.1017864562984974 0.9287625080935471 0.835056692857865 0.9756061175316485 0.7914378062663417 1.0462472243094976 0.6867877717908586 0.800392862252564 1.0 19.682183297351493 -7.768014557656996 24.9998117807692 0.8076928108595585 0.9068053777352928 0.04484822520100573 0.14359530056837824 394.89109146155914 1501403.717511076 0.07118275194029398 0.035458165018874235 1.7060252016636524e-08 7.768014557656996 0.09911256687573433 S(ph)NGDLSPK ddPTM_PC-9_Lapatinib_30min_R1 4 SNGDLSPK 8 0 P49006 P49006 MARCKSL1 MARCKS-related protein 1 S(1)NGDLSPK;S(1)NGDLSPK;S(1)NGDLSPK;S(1)NGDLSPK 111.5 0.0037450000000000005 156699000.0 445848.0 595570.0 396619.0 352434.0 504211.0 475091.0 495090.0 521080.0 498863.0 405547.0 True False 439490.12576149043 594190.9942567111 364010.5168136138 378353.1720453596 474554.3002969668 454772.4654212133 520723.3377060251 545291.2790960637 442675.79567972216 475645.25859259116 0.9239871896587768 1.2492314041243477 0.7652983189419389 0.7954524200764376 0.997706361461791 0.9561168900681585 1.0947724765444264 1.1464242925695325 0.9306847649224469 1.0 18.859526471355004 -7.202257262378502 7.561935794011985 1.0550489980349433 0.948365472630623 0.10541595368291601 0.13376218980642743 0.66554105259206 76.33031260054334 0.05355374270178477 0.04131565015304712 6.276864269854898e-08 7.202257262378502 -0.10668352540432036 S(ph)NIDISSGLEDEEPKRPLPR ddPTM_PC-9_AZD4547_30min_R2 1 SNIDISSGLEDEEPKRPLPR 20 2 Q9BZ71;Q9BZ71-3 Q9BZ71 PITPNM3 Membrane-associated phosphatidylinositol transfer protein 3 1 S(0.998)NIDIS(0.002)SGLEDEEPKRPLPR 70.699 0.0013026 7970000.0 29015.0 31394.0 28472.0 26156.0 23132.0 36108.0 31099.0 35688.0 28122.0 27410.0 True False 38241.1664505084 41541.496556869475 28094.44267672568 20126.138306171655 19920.52108738466 33850.16105193987 33866.75075325411 30173.239628655523 29608.47150779914 26450.384242954693 1.4457697891740189 1.570544162054449 1.062156315714351 0.7609015476413141 0.7531278526772508 1.2797606545529172 1.280387855321037 1.1407486315323547 1.1193966498118315 1.0 14.691001059974903 -5.267450173209234 23.67958165340063 1.0501558620944513 1.5081570059157041 0.5277864410236155 0.17351199524860372 183.325079517415 722217.9295605244 0.051709170561281256 0.11256524652672403 5.401940879071035e-06 5.267450173209234 0.4580011438212528 S(ph)NIDISSGLEDEEPKRPLPR ddPTM_PC-9_Lapatinib_30min_R1 2 SNIDISSGLEDEEPKRPLPR 20 2 Q9BZ71;Q9BZ71-3 Q9BZ71 PITPNM3 Membrane-associated phosphatidylinositol transfer protein 3 1 S(0.63)NIDIS(0.284)S(0.086)GLEDEEPKRPLPR;S(0.999)NIDISSGLEDEEPKRPLPR 95.195 0.0013493000000000001 6476600.0 18971.3 21812.2 22557.0 19755.1 21793.0 20938.8 22879.0 22273.6 23880.0 16024.599999999999 True False 18700.765783089668 21761.695191037583 20702.450532538038 21207.955955081718 20511.17858668652 20043.296334726798 24063.56267219324 23308.512769774497 21190.382932451947 18794.430758562667 0.9950163441140496 1.1578799842673098 1.101520487557522 1.1284170415972539 1.091343433072146 1.0664487045235542 1.280356025746083 1.2401818958605721 1.1274820293664758 1.0 14.19801759957335 -7.223192610468573 24.99788816402705 1.1820202590653164 1.0955017639940072 0.1403158711080741 0.08070184662733003 850.0268366571898 555573.4497245618 0.029610843214801338 0.022935709781460263 5.981462571681545e-08 7.223192610468573 -0.08651849507130915 S(ph)NIVTSINFSKNQLCEIPK ddPTM_PC-9_AZD4547_30min_R2 1 SNIVTSINFSKNQLCEIPK 19 1 Q9H9A6 Q9H9A6 LRRC40 Leucine-rich repeat-containing protein 40 1 S(0.35)NIVT(0.304)S(0.304)INFS(0.042)KNQLCEIPK 44.415 0.042006 32662000.0 39832.0 24066.0 102490.0 221430.0 163820.0 106660.0 64315.0 102900.0 72171.0 123460.0 True False 52497.74744293125 31844.863863719842 101130.9156342236 170382.73455939724 141076.4207390345 99990.53333886963 70038.91040533577 86999.16940676582 75985.81171998323 119137.70297829907 0.44064763824172193 0.26729459329529276 0.8488573567063366 1.4301327816470697 1.1841458850749504 0.8392853885816726 0.5878819941500245 0.7302404464069004 0.6377981933546599 1.0 16.862270523172114 -5.305149671866463 6.350996945311591 0.9143121471886375 0.3539597029398312 0.45541212296830225 0.24224169570148124 0.18957561792727085 20.792517825801358 0.07285599217847923 0.1571712334067287 4.952794721305691e-06 5.305149671866463 -0.5603524442488064 S(ph)NMSPHGLPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNMSPHGLPAR 11 0 H0Y4T7;E7ESY4;Q13330-3;Q13330 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 S(0.758)NMS(0.242)PHGLPAR 73.219 0.017533 8116200.0 12749.0 14249.0 16745.0 17178.0 20630.0 18076.0 15632.0 15434.0 15357.0 12639.0 True False 14907.153895772137 15663.546551639636 17144.264305766137 16215.572351827414 16587.699593694142 17128.06273902064 14151.223794120637 15028.873853674744 15581.56707241036 14930.35064973106 0.9984463356217732 1.0491077483114426 1.1482827636117814 1.0860811465348608 1.1110053596760594 1.1471976205280328 0.9478159037326791 1.006598853989103 1.0436169543473537 1.0 13.865960428122209 -7.262720038801201 24.999134425864025 1.0000578335186538 1.0915836332511473 0.47329131686683823 0.046758266727804136 111.19951946345519 2170650.9910103637 0.019847608620056224 0.014208838856754297 5.461097888480795e-08 7.262720038801201 0.09152579973249342 S(ph)NPDFLKK ddPTM_PC-9_AZD4547_30min_R2 1 SNPDFLKK 8 1 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;H0Y2S9;K7EL39;J3QRL2;H7C3G6;J3QL44;Q6WCQ1;H0Y7E2 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 S(1)NPDFLKK 78.655 0.032054 6456600.0 31163.0 36238.0 36862.0 48555.0 49729.0 35806.0 38887.0 48911.0 29072.0 39685.0 True False 41072.18576933286 47951.22482728663 36373.185794797086 37361.394917271944 42824.98673502297 33567.045159680914 42347.86766589901 41352.92881296708 30608.6865683357 38295.64022917392 1.0725029147846377 1.2521327373124058 0.9497996528358783 0.9756043950091671 1.1182731631784695 0.8765239321970983 1.1058143280142387 1.0798338548591255 0.7992733999265472 1.0 15.224892537293176 -5.270868213515671 24.994202874414754 0.9954077779603315 1.1623178297903705 0.312941662645808 0.10278236596790415 692.4301857272903 1835515.8215292494 0.02581941728917978 0.05492164878272108 5.359592694626946e-06 5.270868213515671 0.16691005183003893 S(ph)NPEGAEDR ddPTM_PC-9_AZD4547_30min_R2 2 SNPEGAEDR 9 0 M0R3H9;M0QXG9;M0R3F4;M0R2A4;M0R2K3;M0R193;M0R0I0;J3KQS6;Q9NWV8-3;Q9NWV8;M0R2I2 M0R3H9 BABAM1 BRISC and BRCA1-A complex member 1 1 S(1)NPEGAEDR;S(1)NPEGAEDR 82.54299999999999 0.015622 5758800.0 2394.5 2180.2 3802.9 4856.299999999999 5769.4 4619.5 3535.0 6791.1 3354.7 4557.0 True False 3155.901191305954 2884.907013865285 3752.47106122928 3736.7550640870713 4968.418397093072 4330.641934735684 3849.6081517975913 5741.691538953219 3532.02259324421 4397.460817042851 0.717664425587354 0.6560392767309047 0.8533267759171745 0.8497528959450552 1.1298380142097937 0.984805121617411 0.8754161348926646 1.3056833881727044 0.8031959215089448 1.0 12.102455007485005 -5.725768051012152 1.5592963942995146 1.021742093107895 0.6862020331669686 0.4670110609415391 0.13440860930658569 0.3292696231808945 1.6113637842375956 0.04120336824532234 0.09633290976318466 1.8803207946964613e-06 5.725768051012152 -0.3355400599409265 S(ph)NPEGAEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNPEGAEDR 9 0 M0R3H9;M0QXG9;M0R3F4;M0R2A4;M0R2K3;M0R193;M0R0I0;J3KQS6;Q9NWV8-3;Q9NWV8;M0R2I2 M0R3H9 BABAM1 BRISC and BRCA1-A complex member 1 1 S(1)NPEGAEDR;S(1)NPEGAEDR 82.069 0.016313 7663400.0 2592.1 3328.3 3771.4 4364.799999999999 5947.6 5957.700000000001 4573.2 5332.9 3879.2 3409.0 True False 3030.8913336913465 3658.7116280315945 3861.3244791141483 4120.254406872527 4782.210475203841 5645.267724068558 4139.993388899215 5192.917025674614 3935.9259612746155 4027.0247143708507 0.7526378775067607 0.9085396508680731 0.9588529380846896 1.0231510107621085 1.1875294577006277 1.401845810362882 1.028052639986346 1.2895170489376826 0.9773781489914527 1.0 11.975498610978745 -5.5919515151087715 1.315507054550842 1.1647040684537437 0.7990930173431391 0.48664311105184876 0.12931036275282493 0.40920996760409467 1.3296928089996536 0.041957218062127974 0.1346834391117146 2.5588715448831562e-06 5.5919515151087715 -0.36561105111060466 S(ph)NPEGAEDR ddPTM_PC-9_Lapatinib_30min_R1 2 SNPEGAEDR 9 0 M0R3H9;M0QXG9;M0R3F4;M0R2A4;M0R2K3;M0R193;M0R0I0;J3KQS6;Q9NWV8-3;Q9NWV8;M0R2I2 M0R3H9 BABAM1 BRISC and BRCA1-A complex member 1 1 S(1)NPEGAEDR;S(1)NPEGAEDR 74.46 0.027395999999999997 7585900.0 2165.11 3268.2200000000003 2796.96 3727.7999999999997 5898.1 3922.3799999999997 4221.9 3488.8 6692.1 6107.3 True False 2134.235134367455 3260.6526373888396 2567.004745377823 4001.954847576256 5551.1853541107575 3754.6289509143653 4440.489324084648 3650.902384490577 5938.365227062881 7162.938667534283 0.29795524343113333 0.4552115812700743 0.3583731293152995 0.5587029337155918 0.7749871403019645 0.5241743822171845 0.6199256380919438 0.5096933750163376 0.8290403565757544 1.0 12.80633587372845 -8.114055679103 0.11570884635865934 1.3787044001292086 8.762312106378239e-13 0.7233925210726072 0.10895208223290663 4.559315865215077 0.5192705372348015 2.910988680707609 2.683118728191313 7.690318395681313e-09 8.114055679103 -1.3787044001283324 down S(ph)NPSIQATLNK ddPTM_PC-9_AZD4547_30min_R2 1 SNPSIQATLNK 11 0 Q6UUV7;Q6UUV7-3 Q6UUV7 CRTC3 CREB-regulated transcription coactivator 3 1 S(1)NPSIQATLNK 150.9 0.00025521 7145900.0 20690.0 30236.0 54865.0 71509.0 95988.0 92452.0 83383.0 102370.0 74362.0 78233.0 True False 27268.9896212655 40009.19570279371 54137.45425184586 55023.70485303673 82661.72307348582 86670.9618249124 90803.925465725 86551.06872857739 78292.62350696826 75494.08648227193 0.3612069619210374 0.5299646312322616 0.7171085415353534 0.7288478795747505 1.0949430203767951 1.1480496799608948 1.2027952081657183 1.146461567541478 1.0370696190270943 1.0 16.204076020850373 -5.787383004794182 1.0398388265019345 1.1341077166129436 0.39533390730433277 0.9116153430922892 0.08252839461481948 0.16378486412286622 0.34023176197623484 0.03282590603540211 0.09260297286750463 1.6316123924028517e-06 5.787383004794182 -0.7387738093086109 down S(ph)NPSIQATLNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNPSIQATLNK 11 0 Q6UUV7;Q6UUV7-3 Q6UUV7 CRTC3 CREB-regulated transcription coactivator 3 1 S(0.999)NPS(0.001)IQATLNK 169.04 0.0022675 10892000.0 15514.0 16540.0 23939.0 41555.0 51125.0 39624.0 47859.0 36758.0 38230.0 37993.0 True False 18140.21378453282 18181.9818909481 24509.79654916306 39226.80807312772 41107.42325388331 37546.04768593459 43325.44905084572 35793.14144832033 38789.04142594568 44880.8301475775 0.4041862355238089 0.4051168802172768 0.5461083600407959 0.8740214462197294 0.9159238614507252 0.8365720411693673 0.9653441994807723 0.7975151379915444 0.8642674678342457 1.0 15.45381174085081 -5.6593338748499535 2.8851806821952692 0.8899759508367978 0.41082350616109997 0.9302371865504119 0.0562477012549577 0.05910362487609263 0.9848402036473964 0.01579008025951866 0.030234122297353644 2.1911198090074575e-06 5.6593338748499535 -0.47915244467569784 S(ph)NPSIQATLNK ddPTM_PC-9_Lapatinib_30min_R1 2 SNPSIQATLNK 11 0 Q6UUV7;Q6UUV7-3 Q6UUV7 CRTC3 CREB-regulated transcription coactivator 3 1 S(1)NPSIQATLNK;S(1)NPSIQATLNK 144.8 1.0800000000000002e-05 0.0 78626.0 79123.0 72039.0 72727.0 66859.0 76202.0 59026.0 68862.0 70791.0 45184.0 True False 77504.77882175763 78939.79555480268 66116.23149858168 78075.58619015975 62926.48506985145 72943.01809553802 62082.07746356386 72061.57991309039 62817.77211772223 52993.9941961045 1.4625200458555903 1.4895989017677294 1.2476174423448492 1.473291216760162 1.1874267268285483 1.376439334344418 1.1714927022452557 1.3598065404624193 1.1853753065916262 1.0 15.693541248009174 -7.935630232013131 0.042920592864497835 1.0520776275988878e-10 2.4806214315161785 0.6259225122644207 0.09409077585849117 32.405501089007174 1.427552646723135 40.616940139312874 40.67933899269542 1.159764385113671e-08 7.935630232013131 2.4806214314109707 S(ph)NQIPTEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SNQIPTEVR 9 0 Q9BWH2 Q9BWH2 FUNDC2 FUN14 domain-containing protein 2 1 S(1)NQIPTEVR;S(1)NQIPTEVR;S(1)NQIPTEVR;S(1)NQIPTEVR 122.55 0.0015497 28468500.0 138812.0 163363.0 140906.0 99522.0 203864.0 78193.0 131874.0 83533.0 85085.0 95432.0 True False 162310.1299380286 179580.59901154527 144265.73342898063 93946.10499467752 163918.31264996936 74092.42142909061 119381.9400349196 81340.3472605295 86329.20715999427 112733.06616070344 1.439773932048047 1.5929718327322813 1.2797108988708485 0.8333500382288485 1.4540393358617625 0.6572377027647793 1.0589789145337185 0.7215305147877115 0.7657842556764145 1.0 16.782551214340977 -5.580966985649096 0.6271257552722368 0.8344157265550337 1.6974128921498626 0.5363188179863893 0.22022997109002368 1.1445183082026507 0.6528012651530825 0.12130704225527585 0.6269134572712115 2.624418039736642e-06 5.580966985649096 0.8629971655948289 S(ph)NSAPLIHGLSDTSPVFQAEAPSAR ddPTM_PC-9_AZD4547_30min_R2 2 SNSAPLIHGLSDTSPVFQAEAPSAR 25 0 Q96E09 Q96E09 FAM122A Protein FAM122A 1 S(0.505)NS(0.495)APLIHGLSDTSPVFQAEAPSAR;S(0.631)NS(0.369)APLIHGLSDTSPVFQAEAPSAR 119.25 3.0059e-09 41399000.0 33578.7 31125.1 60957.8 92787.7 76067.8 73520.6 53377.5 79229.2 62169.7 65374.0 True False 44256.02811965143 41185.67989049559 60149.459742881045 71396.92932067465 65507.0989958049 68923.34525964461 58127.99409408091 66986.1476458943 65455.8634200419 63085.276158296925 0.7015270569411769 0.6528572497194162 0.9534627318100475 1.1317526635140929 1.0383896684771738 1.0925424989295203 0.9214193490763687 1.061834895955898 1.0375775047064322 1.0 15.945015705009034 -5.355687936182486 3.854847749867255 1.0402647847876094 0.6751570326784233 0.8717859258424473 0.054758799818571215 0.06888323771429876 1.8501533548784652 0.014545185951956112 0.033612785189110615 4.408715395038407e-06 5.355687936182486 -0.3651077521091861 S(ph)NSAWQIYLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSAWQIYLQR 11 0 Q8N4C8;Q8N4C8-4 Q8N4C8 MINK1 Misshapen-like kinase 1 1 S(0.98)NS(0.02)AWQIYLQR 183.89 0.0013142000000000002 15885000.0 58212.0 55336.0 43852.0 50088.0 59636.0 38695.0 43942.0 46356.0 43602.0 32923.0 True False 68066.14186059196 60829.3923771163 44897.59798963609 47281.73174748702 47950.753900608026 36665.7660813456 39779.4956474699 45139.204118241934 44239.596763120186 38891.67928167539 1.7501466410750415 1.5640721486093638 1.1544268290515938 1.21572872708957 1.232930919575926 0.9427663386759807 1.0228279257206778 1.1606391123231903 1.137508011487809 1.0 15.247173908974196 -4.824123795754892 0.9408131923297337 1.080621830602452 2.131200279867882 0.8654044239082928 0.08822921851348732 0.6941228845692596 0.5066342584946424 0.031823521590274934 0.7385488585579408 1.499257410872054e-05 4.824123795754892 1.05057844926543 S(ph)NSDESNFSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSDESNFSEK 11 0 O95999;A0A087WWW9 O95999 BCL10 B-cell lymphoma/leukemia 10 1 S(0.765)NS(0.234)DESNFSEK 126.56 0.00040436 6903100.0 26115.0 23936.0 12301.0 24189.0 31890.0 29516.0 33437.0 28938.0 25608.0 18325.0 True False 30535.753705238818 26312.20789248693 12594.302491802284 22833.768751796095 25641.38342428046 27968.129000051606 30269.60529708367 28178.408162345437 25982.468554423678 21647.17743937981 1.4106113275391372 1.2155029433361901 0.5817988292963846 1.0548150591798484 1.1845139393385542 1.2919988796864081 1.3983164956193426 1.3017128094993222 1.2002705030336773 1.0 14.401891304747334 -6.417977426264507 3.473733476111686 1.265328572160783 1.0431050647156126 0.11403398345687354 0.21735397811653784 0.4690558725586093 10.500146354264055 0.07493148491680326 0.08466902958050677 3.8196412403501173e-07 6.417977426264507 -0.2222235074451704 S(ph)NSDESNFSEK ddPTM_PC-9_Lapatinib_30min_R1 3 SNSDESNFSEK 11 0 O95999;A0A087WWW9 O95999 BCL10 B-cell lymphoma/leukemia 10 1 S(0.68)NS(0.047)DES(0.036)NFS(0.237)EK;S(0.8)NS(0.2)DESNFSEK;S(0.62)NS(0.38)DESNFSEK 179.5 0.00034839 53344200.0 166881.0 171739.0 155549.0 147999.0 200923.0 182158.0 192999.0 178568.0 220623.0 217197.0 True False 164501.24633777252 171341.34889711277 142760.3616565037 158883.3401701912 189105.10416981654 174367.52697103765 202991.54386864044 186864.92117453332 195774.11447681504 254739.21205318917 0.6457633475894747 0.6726147400555551 0.5604176934750648 0.6237097888840788 0.7423478413301038 0.6844942542046882 0.7968602172886368 0.733553816345778 0.7685275969054096 1.0 17.958661525452378 -9.874447812721938 0.1930212159396407 1.2046901334087141 0.5655024259441186 0.8426068759649968 0.045411227062647594 5.0973953639824545 0.2967854173013819 0.7936638931353168 0.17631357656633356 1.3352180272627767e-10 9.874447812721938 -0.6391877074645955 S(ph)NSDNNLNASAPDWAVCSTATSHR ddPTM_PC-9_AZD4547_30min_R2 1 SNSDNNLNASAPDWAVCSTATSHR 24 0 Q9UPX8;Q9UPX8-3;A0A2R8Y2H5;A0A087X158 Q9UPX8 SHANK2 SH3 and multiple ankyrin repeat domains protein 2 1 S(0.5)NS(0.5)DNNLNASAPDWAVCSTATSHR 168.04 2.5971e-10 26070000.0 8837.0 7133.3 9939.1 22175.0 14104.0 11918.0 6255.5 14165.0 15467.0 14201.0 True False 11646.982178981305 9438.99972571565 9807.30103990743 17062.89635033478 12145.903052761245 11172.765575967076 6812.227381490756 11976.124729318133 16284.554043493685 13703.827312447986 0.8499072495171967 0.6887856589627086 0.7156614583868032 1.2451190431183816 0.886314660556793 0.8153025662997229 0.49710400066869 0.8739255432998284 1.188321603315993 1.0 13.742291256206252 -8.135917362451792 5.841610826520357 1.0890818066644974 0.8159312823570778 0.26475488994829355 0.18349840723220157 0.3273895465149673 13.860816237119815 0.13654839248801545 0.05012366389327227 7.31278217855267e-09 8.135917362451792 -0.2731505243074196 S(ph)NSDNNLNASAPDWAVCSTATSHR ddPTM_PC-9_Lapatinib_30min_R1 2 SNSDNNLNASAPDWAVCSTATSHR 24 0 Q9UPX8;Q9UPX8-3;A0A2R8Y2H5;A0A087X158 Q9UPX8 SHANK2 SH3 and multiple ankyrin repeat domains protein 2 1 S(0.5)NS(0.5)DNNLNASAPDWAVCSTATSHR;S(0.5)NS(0.5)DNNLNASAPDWAVCSTATSHR 177.71 9.594e-15 42917000.0 6496.8 6156.1 5229.5 3986.5 6042.4 12821.2 8736.1 4827.4 14502.8 4662.5 True False 6404.154440632798 6141.845928679655 4799.550696453767 4279.680508574157 5686.99791181547 12272.867163676963 9188.412511934406 5051.698627290129 12869.341942745557 5468.406912609267 1.1711188547190676 1.1231508603570715 0.8776871899175562 0.7826192485248129 1.0399734333416497 2.2443222239694167 1.6802722728528858 0.9237971328800941 2.353398740878431 1.0 12.416904884767956 -6.564899340227259 23.85483042739544 1.638542378282858 0.9804473549729822 0.35106984551897225 0.43643360112352225 99.49971442042981 56484.43488868867 0.13946206330134514 0.13946223399249205 2.723332442642217e-07 6.564899340227259 -0.6580950233098759 S(ph)NSELEDEILCLEK ddPTM_PC-9_AZD4547_30min_R2 4 SNSELEDEILCLEK 14 0 Q96PC5;Q96PC5-11;Q96PC5-13;G3V599;Q96PC5-10;Q96PC5-9;Q96PC5-6;Q96PC5-12;Q96PC5-7;Q96PC5-14;Q96PC5-5;Q96PC5-8;Q86UF2;A0A5F9ZHA4;G3V5K6;P0CG41;A4D2H0;A0A2R8YE69;Q8IX94;A4FU28 Q96PC5 MIA2;CTAGE6;CTAGE5;CTAGE8;CTAGE15;CTAGE4;CTAGE9 Melanoma inhibitory activity protein 2;cTAGE family member 6;cTAGE family member 8;cTAGE family member 15;cTAGE family member 4;cTAGE family member 9 1 S(1)NSELEDEILCLEK;S(0.988)NS(0.012)ELEDEILCLEK;S(0.976)NS(0.024)ELEDEILCLEK;S(0.997)NS(0.003)ELEDEILCLEK 207.53 1.5096999999999997e-60 3815000.0 25352.1 32363.6 36980.6 32999.6 33665.4 24199.4 31333.100000000002 39468.0 29214.8 24165.2 True False 33413.54044356139 42824.50079530801 36490.2130813052 25392.052058737663 28991.540317103547 22686.2076924868 34121.68519974235 33369.12748441427 30759.03468480372 23319.183703314433 1.4328777914645534 1.8364493946338794 1.5648151987463748 1.0888911199378135 1.243248506721223 0.9728559962097788 1.4632452676674321 1.4309732239757347 1.3190442288265791 1.0 14.509229666896081 -5.641358530895703 5.823228907531607 1.2371498263934806 1.6492564254514943 0.49916619725475353 0.18072174419546225 0.17150380858448766 8.020154534754855 0.050150659995874515 0.08784688174843158 2.283712710729634e-06 5.641358530895703 0.4121065990580137 S(ph)NSELEDEILCLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SNSELEDEILCLEK 14 0 Q96PC5;Q96PC5-11;Q96PC5-13;G3V599;Q96PC5-10;Q96PC5-9;Q96PC5-6;Q96PC5-12;Q96PC5-7;Q96PC5-14;Q96PC5-5;Q96PC5-8;Q86UF2;A0A5F9ZHA4;G3V5K6;P0CG41;A4D2H0;A0A2R8YE69;Q8IX94;A4FU28 Q96PC5 MIA2;CTAGE6;CTAGE5;CTAGE8;CTAGE15;CTAGE4;CTAGE9 Melanoma inhibitory activity protein 2;cTAGE family member 6;cTAGE family member 8;cTAGE family member 15;cTAGE family member 4;cTAGE family member 9 1 S(0.998)NS(0.002)ELEDEILCLEK;S(0.994)NS(0.006)ELEDEILCLEK;S(0.999)NS(0.001)ELEDEILCLEK 193.42 1.6420000000000003e-07 4289200.0 16160.599999999999 20283.1 18734.8 14609.599999999999 20830.5 15828.800000000001 19437.600000000002 16550.1 13365.599999999999 12752.3 True False 18896.270393600687 22296.672121661977 19181.508684124663 13791.07147696226 16748.913057995433 14998.709862990137 17596.329811962598 16115.677411280445 13561.046614769022 15064.191042848737 1.2543833478911641 1.4801108176496898 1.2733182040485669 0.9154870273308933 1.1118362088182934 0.995653189761578 1.1680899267615115 1.069800387252183 0.9002173814840667 1.0 13.878835580871716 -5.602838982557318 5.447524452451329 1.0356247327245047 1.3698431104448539 0.7085353651579462 0.0928897888516457 0.1002463196616476 5.030178313859404 0.02453625891963703 0.043421543928036245 2.4955197852866878e-06 5.602838982557318 0.3342183777203491 S(ph)NSELEDEILCLEK ddPTM_PC-9_Lapatinib_30min_R1 1 SNSELEDEILCLEK 14 0 Q96PC5;Q96PC5-11;Q96PC5-13;G3V599;Q96PC5-10;Q96PC5-9;Q96PC5-6;Q96PC5-12;Q96PC5-7;Q96PC5-14;Q96PC5-5;Q96PC5-8;Q86UF2;A0A5F9ZHA4;G3V5K6;P0CG41;A4D2H0;A0A2R8YE69;Q8IX94;A4FU28 Q96PC5 MIA2;CTAGE6;CTAGE5;CTAGE8;CTAGE15;CTAGE4;CTAGE9 Melanoma inhibitory activity protein 2;cTAGE family member 6;cTAGE family member 8;cTAGE family member 15;cTAGE family member 4;cTAGE family member 9 1 S(0.963)NS(0.037)ELEDEILCLEK 153.75 2.7313e-05 1676500.0 11868.0 15744.0 8737.0 7823.5 8774.5 8008.7 7803.1 8930.3 11551.0 4192.7 True False 11698.760143675343 15707.545735308477 8018.677585795306 8398.866288430934 8258.401161330736 7666.186570191534 8207.10633713847 9345.234339662971 10250.004742577574 4917.402608578418 2.379052738790766 3.194276935532314 1.6306733908276512 1.7079883338775426 1.6794234311674907 1.5589910325458927 1.6689921469560287 1.90044116447984 2.08443472265143 1.0 12.26368076420965 -5.272988936217133 24.94573757429987 1.6860238425778735 2.786664829302987 0.6655382894583081 0.3205693802894637 346.11431419064695 747568.3090089925 0.07905371906122087 0.16678281017541224 5.333484825279512e-06 5.272988936217133 1.1006409867251137 S(ph)NSFNNPLGNR ddPTM_PC-9_AZD4547_30min_R2 1 SNSFNNPLGNR 11 0 O95835;O95835-2 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 S(0.957)NS(0.043)FNNPLGNR 128.36 0.0003137 20275000.0 23881.0 27903.0 44346.0 42651.0 31032.0 23105.0 27575.0 42301.0 29076.0 27318.0 True False 31474.661244342242 36922.099077095285 43757.94306483835 32818.4709013812 26723.74245131077 21660.2406974928 30029.12158014671 35764.35243027787 30612.898000169513 26361.605134952057 1.1939584514378048 1.4006013248465432 1.6599119378668263 1.2449344694063482 1.013737301446738 0.8216586428105678 1.1391234117353501 1.356683413137806 1.1612683614466555 1.0 14.68615059700212 -5.997252012415934 24.90672583371437 1.0933431945284808 1.422405288261013 0.4535446895717805 0.16552735478805605 82.16899643294812 744726.0908445877 0.05098551875071591 0.07513957666576568 1.0063475360073055e-06 5.997252012415934 0.32906209373253215 S(ph)NSFNNPLGNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSFNNPLGNR 11 0 O95835;O95835-2 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 S(0.958)NS(0.042)FNNPLGNR 134.18 5.9093999999999994e-05 16303000.0 18904.0 18026.0 17821.0 18955.0 21119.0 16747.0 21357.0 23349.0 16564.0 18248.0 True False 22104.073828980843 19815.50215031623 18245.92022651885 17893.012802939156 16980.883554010004 15868.75783859142 19333.910348709982 22736.11349031045 16806.217163990706 21556.21794891149 1.0254152134371521 0.9192476248514105 0.846434206119177 0.8300627153309464 0.7877487411871097 0.7361568655596533 0.8969064236839502 1.0547357400168864 0.7796459102344231 1.0 14.395816458150936 -9.806121161124567 9.980585346078971 1.0000079433182092 0.8735397834709183 0.12707419710366497 0.09808594388421407 0.0 0.0 0.09983784002953888 0.02421423293384164 1.5627116105985426e-10 9.806121161124567 -0.12646815984729087 S(ph)NSFNNPLGNR ddPTM_PC-9_Lapatinib_30min_R1 1 SNSFNNPLGNR 11 0 O95835;O95835-2 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 S(0.735)NS(0.265)FNNPLGNR 140.45 0.00012132 15641000.0 36912.0 40060.0 44826.0 34410.0 31181.0 38616.0 29798.0 25415.0 43605.0 29358.0 True False 36385.62811116823 39967.243531279084 41140.57931336394 36940.62618839501 29346.99488420466 36964.48369829264 31340.79463726624 26595.873682019035 38693.7457189936 34432.49118292396 1.056723660157732 1.1607421408736167 1.1948185536388582 1.0728421011464573 0.852305304553702 1.073534978980097 0.9102099081581708 0.7724063164854211 1.1237567887095814 1.0 15.07148294289219 -6.045417892304283 6.149395514452253 0.9481640714454466 1.1393116179730893 0.4048206491845324 0.10058561297011756 0.19127337452098386 18.55759211859203 0.028961893570575936 0.03842316964980439 9.007040337195737e-07 6.045417892304283 0.19114754652764276 S(ph)NSFSDEREFSGPSTPTGTLEFEGGEVSLEGGK ddPTM_PC-9_AZD4547_30min_R2 1 SNSFSDEREFSGPSTPTGTLEFEGGEVSLEGGK 33 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(0.341)NS(0.288)FS(0.136)DEREFS(0.048)GPS(0.044)T(0.044)PT(0.048)GT(0.048)LEFEGGEVS(0.001)LEGGK 41.513999999999996 0.019221000000000002 4218300.0 22358.0 19513.0 27656.0 39060.0 34886.0 29947.0 22370.0 28756.0 25223.0 34509.0 True False 29467.378924710192 25820.19565248753 27289.263369890625 30055.320470984287 30042.68107619318 28074.40935588907 24360.886663567795 24312.42094714239 26556.23628622494 33300.85041372211 0.8848836759005927 0.7753614496838176 0.8194764707463951 0.9025391273070776 0.9021595755949118 0.8430538261665712 0.7315394760468198 0.7300840862948081 0.7974642075591574 1.0 15.023271399848802 -7.027074147518582 23.71365294349465 0.7915671718431295 0.8547925699585027 0.02722233437476007 0.07990487113185499 842.7110706398865 738109.135614188 0.029790421686154214 0.023158064001995295 9.395628843866306e-08 7.027074147518582 0.0632253981153732 S(ph)NSGRELTDEEILASVMIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSGRELTDEEILASVMIK 19 1 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 S(0.526)NS(0.358)GRELT(0.115)DEEILASVMIK 80.844 0.0035776 8785500.0 27911.0 16405.0 25767.0 34786.0 41955.0 32659.0 30291.0 33172.0 29699.0 24689.0 True False 32635.781032621882 18033.57998313202 26381.383001891667 32837.05319773365 33734.2189264875 30946.304547116335 27421.617192151236 32301.270148639265 30133.291690012058 29164.920261983538 1.1190080665217046 0.6183311945014567 0.9045587220850314 1.1259092396880899 1.1566710494477175 1.061079689885346 0.9402260299643371 1.1075384351639719 1.0332032942085836 1.0 14.831946509322654 -5.623855474684763 5.622187956020515 1.063253006955199 0.8438458984891495 0.29362388200245537 0.12714886491521715 0.21193829307194373 9.867315582152985 0.033343668627361225 0.05863870560030501 2.377631387525051e-06 5.623855474684763 -0.2194071084660496 S(ph)NSLNNGQPK ddPTM_PC-9_AZD4547_30min_R2 1 SNSLNNGQPK 10 0 O60333-3 O60333-3 KIF1B Kinesin-like protein KIF1B 1 S(0.709)NS(0.291)LNNGQPK 76.165 0.023511 27755000.0 64009.0 56222.0 65328.0 89452.0 77442.0 70264.0 61454.0 79313.0 67449.0 69587.0 True False 84362.53053009116 74394.6620188671 64461.70803544305 68830.22341962322 66690.51504622343 65870.3809724577 66923.28694782722 67056.99828142676 71014.21644013732 67150.78031063436 1.2563149696822071 1.1078748701760885 0.9599547129199114 1.0250100311749153 0.9931457942516561 0.9809324726793399 0.9966122007554524 0.9986034111774461 1.0575337488504377 1.0 16.03511654381485 -4.899405648495366 2.6804630283203013 1.001278985123953 1.2756083312692774 0.9048736426760452 0.025649687999054694 0.09475641502127381 1.0983793234451775 0.006560997794438929 0.05224989987228253 1.26064948723255e-05 4.899405648495366 0.27432934614532445 S(ph)NSLNNGQPK ddPTM_PC-9_Lapatinib_30min_R1 1 SNSLNNGQPK 10 0 O60333-3 O60333-3 KIF1B Kinesin-like protein KIF1B 1 S(0.606)NS(0.394)LNNGQPK 116.74 0.0010155 30153000.0 110060.0 109980.0 106100.0 111680.0 103600.0 117710.0 105970.0 103490.0 116780.0 114800.0 True False 108490.52421746813 109725.34806715092 97376.86755784375 119893.31975355854 97506.4516854367 112675.81769541204 111456.60808480781 108298.5232088197 103627.00665208278 134643.02703861534 0.8057641498683276 0.814935243810895 0.7232225069473243 0.8904532406210192 0.7241849342667559 0.836848518439034 0.8277933921735308 0.8043381494814426 0.7696425795772014 1.0 17.038779991188406 -10.90341463124761 3.1181162898747843 1.0023217362716084 0.8003918858595953 0.6092855177940497 0.048119697364391985 17574159.617975574 22004714.961261358 368101.0876573516 0.011288941322742944 1.2490659478757643e-11 10.90341463124761 -0.20192985041201306 S(ph)NSLPHPAGGGK ddPTM_PC-9_AZD4547_30min_R2 1 SNSLPHPAGGGK 12 0 G5E9A7;Q09019 G5E9A7 DMWD Dystrophia myotonica WD repeat-containing protein 1 S(0.621)NS(0.379)LPHPAGGGK 64.842 0.024391999999999997 12617000.0 40182.0 37455.0 59830.0 67308.0 59090.0 55387.0 56037.0 57382.0 58660.0 59139.0 True False 52959.040162478974 49561.59627755447 59036.61510777247 51791.18049823369 50886.37346764477 51923.64213425813 61024.184441946745 48514.930407182 61760.64784323647 57068.561610510675 0.9279897489605762 0.8684570782738354 1.0344857736330142 0.9075255979238661 0.8916708610064689 0.9098466943784864 1.0693135190340515 0.8501165797430349 1.0822184071284113 1.0 15.800408580490313 -7.864016675424475 0.8705867915783648 1.0148993515074451 0.9269424812103522 0.1660696450638598 0.07368723679553121 1.1562892847699753 1.6360573651637829 0.06508187136583488 0.026911245682798315 1.3676763104895673e-08 7.864016675424475 -0.08795687029709298 S(ph)NSLPHPAGGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSLPHPAGGGK 12 0 G5E9A7;Q09019 G5E9A7 DMWD Dystrophia myotonica WD repeat-containing protein 1 S(0.733)NS(0.267)LPHPAGGGK 63.211999999999996 0.027464999999999996 3132700.0 33170.0 33159.0 38351.0 39453.0 47686.0 42413.0 43683.0 44770.0 37745.0 24351.0 True False 38785.02586263724 36450.806379803376 39265.43328697744 37242.57631835178 38342.27061681525 40188.78761618071 39545.03000246749 43594.834937736065 38296.949218475514 28765.643537590073 1.348310730888191 1.267164641464411 1.3650114670880404 1.2946894885102884 1.3329189234619672 1.3971106734901728 1.3747312814605117 1.515517456815025 1.3313433842851532 1.0 14.812059125735601 -8.567978792428844 23.11114127021373 0.9999999998162536 1.3614016008896905 0.7466789402190976 0.06287391405216039 7205.349923038695 3692311.9888760396 0.06502567866883611 0.016789558012607824 2.7040904076690277e-09 8.567978792428844 0.3614016010734369 S(ph)NSLPHSAVSNAGSK ddPTM_PC-9_AZD4547_30min_R2 1 SNSLPHSAVSNAGSK 15 0 A0A088AWN2;Q8TBZ3-4;Q8TBZ3-5;Q8TBZ3-6;Q8TBZ3;Q8TBZ3-2;Q8TBZ3-7 A0A088AWN2 WDR20 WD repeat-containing protein 20 1 S(0.497)NS(0.497)LPHS(0.006)AVSNAGSK 90.45299999999999 0.0023886999999999997 98685000.0 231070.0 184880.0 542160.0 869000.0 672760.0 554450.0 390650.0 703740.0 454040.0 527430.0 True False 304545.4534454243 244638.84447455013 534970.6041589486 668665.4759161626 579358.8866829026 519780.1538508931 425417.0932106736 594993.1533364176 478039.62745896925 508964.8362371988 0.5983624638922864 0.48065961940156166 1.0510954118441889 1.313775389395539 1.1383082787528709 1.0212496362099441 0.8358477107294924 1.1690260524385736 0.9392390071446565 1.0 18.957206460131438 -5.266569185108076 24.2375490688617 1.0672797236542062 0.5395110088446909 0.7290923988837228 0.1264701304293557 128.00013469690722 604786.0911598293 0.03470759383367733 0.0760424952933973 5.412910108667277e-06 5.266569185108076 -0.5277687148095153 S(ph)NSLPHSAVSNAGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNSLPHSAVSNAGSK 15 0 A0A088AWN2;Q8TBZ3-4;Q8TBZ3-5;Q8TBZ3-6;Q8TBZ3;Q8TBZ3-2;Q8TBZ3-7 A0A088AWN2 WDR20 WD repeat-containing protein 20 1 S(0.491)NS(0.491)LPHS(0.017)AVSNAGSK;S(0.786)NS(0.115)LPHS(0.098)AVS(0.002)NAGSK 115.87 0.00015326 15255300.0 43420.5 47064.1 74299.0 76847.0 94412.0 84785.0 85997.0 84545.0 76997.0 56585.0 True False 50770.733056033736 51736.31281219893 76070.5699405268 72541.51173133565 75912.64634221271 80338.72534453786 77850.74159563662 82325.78333283217 78122.93546098706 66843.41257338635 0.7595472927162917 0.773992691581963 1.138041386756101 1.0852454855097866 1.1356787964538673 1.2018944313523074 1.1646733552115625 1.2316214891399802 1.168745467254789 1.0 16.028497769097918 -5.261949458959114 5.2794220621275905 1.151079409681179 0.7613961150535057 0.8578678214077504 0.060806913874414545 0.05203830391806954 5.102214647175892 0.0158463630010819 0.0386706809385777 5.470796256068468e-06 5.261949458959114 -0.38968329462767326 S(ph)NSMLELAPK ddPTM_PC-9_Lapatinib_30min_R1 1 SNSMLELAPK 10 0 Q9P2M7-2;Q9P2M7;A6PVU7;A2A3M4 Q9P2M7-2 CGN Cingulin 1 S(0.758)NS(0.242)MLELAPK 111.12 0.0016408000000000002 3528000.0 40694.0 38663.0 37909.0 40088.0 35896.0 35722.0 33014.0 29589.0 36408.0 27588.0 True False 40113.6960976344 38573.478198947625 34792.26835297178 43036.20524964772 33784.66785425132 34194.25333204915 34723.30338125739 30963.81295995519 32307.347646763406 32356.549041300685 1.2397396287976292 1.192138202059543 1.0752774750039655 1.3300616575245792 1.0441369322521925 1.0567954353971054 1.0731460681092946 0.9569565938701382 0.9984793991944421 1.0 14.981770126177329 -6.418465679762624 7.883797204983242 1.021423783643295 1.1983017243222676 0.6611855464127536 0.06583445515163168 0.19059634241402554 12.883985240719342 0.020484704638836233 0.023209835738940685 3.8153494398893515e-07 6.418465679762624 0.17687794067897267 S(ph)NSMPTTGYSAVPANIIPPPHPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNSMPTTGYSAVPANIIPPPHPLR 24 0 F5H212;P15822 F5H212 HIVEP1 Zinc finger protein 40 1 S(0.393)NS(0.393)MPT(0.136)T(0.073)GY(0.002)S(0.003)AVPANIIPPPHPLR;S(0.487)NS(0.487)MPT(0.013)T(0.013)GY(0.001)SAVPANIIPPPHPLR 103.85 1.2495999999999999e-06 8717000.0 4345.0 7135.799999999999 7545.9 6396.0 5784.2 4665.3 5818.5 4337.6 3017.2 4092.8999999999996 True False 5080.522682338218 7844.195065140712 7725.822873985107 6037.652856111781 4650.827532227126 4420.643455208729 5267.32955770797 4223.742596067097 3061.320842018397 4834.910370621425 1.0507997652260976 1.6224075450921975 1.5979247352608354 1.2487621058703866 0.9619263183216695 0.9143175604805576 1.0894368569299802 0.8735927395328789 0.6331701329191195 1.0 12.239273429988085 -6.152734976907911 2.852007186518171 0.9095561673291913 1.4426203641421447 0.6201418431474859 0.18264775737368846 0.1774717700921172 2.792513226324964 0.05820525957837913 0.07846681164300325 7.035014924210795e-07 6.152734976907911 0.5330641968129534 S(ph)NSPGTASSGSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSPGTASSGSSR 13 0 H0YAP0;Q96GY0 H0YAP0 ZC2HC1A Zinc finger C2HC domain-containing protein 1A 1 S(0.805)NS(0.189)PGT(0.006)ASSGSSR 113.43 0.00034541 1994400.0 5645.5 7400.9 6729.6 4518.7 8373.6 8633.8 7161.6 5574.3 5488.7 6219.6 True False 6601.171646292385 8135.612441155849 6890.059186150125 4265.531888823061 6732.853190390557 8181.028329063754 6483.201402506038 5427.980531459055 5568.961853899769 7347.164245673491 0.8984652344174289 1.1073132666044114 0.9377848317747164 0.5805684678050985 0.9163880056656305 1.113494683868174 0.8824086662175529 0.7387857886334062 0.7579743241998642 1.0 12.842971811057291 -7.532208016250943 23.951267781317373 0.8111474059517109 0.9250000516025602 0.06542477974473582 0.15233911110614248 324.97402642179367 834292.4896072217 0.07591778005450892 0.04392063042987682 2.9362429277911414e-08 7.532208016250943 0.1138526456508493 S(ph)NSPLPSIQLQPQSPSASKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNSPLPSIQLQPQSPSASKK 20 1 Q08174-2;Q08174 Q08174-2 PCDH1 Protocadherin-1 1 S(0.576)NS(0.423)PLPSIQLQPQSPSASKK;S(0.473)NS(0.473)PLPS(0.054)IQLQPQSPSASKK 98.01899999999999 0.0011219000000000001 0.0 21027.0 16969.300000000003 19263.3 23887.0 37535.0 25825.0 25234.0 21325.0 26269.0 21742.5 True False 24586.455797819497 18653.899957803234 19722.610128472057 22548.6888326989 30180.286197252037 24470.69153768575 22843.652841660718 20765.241345705173 26653.134428934532 25684.2431364647 0.9572583341151042 0.7262779696754905 0.767887534146228 0.8779191472722762 1.1750506346205767 0.9527511247915251 0.8894033871385095 0.8084817308174493 1.0377231786555652 1.0 14.648595940508713 -6.005137584272296 24.43832154669923 0.9679016426551268 0.8105296348191721 0.3209941107807376 0.10538893771858213 215.33498035053992 1024315.251317967 0.031290443317512094 0.04492694853513934 9.882399711376504e-07 6.005137584272296 -0.15737200783595473 S(ph)NSPLPVPPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNSPLPVPPSK 11 0 Q13247-3;Q13247 Q13247-3 SRSF6 Serine/arginine-rich splicing factor 6 1 S(0.98)NS(0.02)PLPVPPSK;S(0.877)NS(0.123)PLPVPPSK 162.67 0.00013315 639120000.0 1619380.0 2083540.0 1775510.0 1923440.0 2087800.0 1900910.0 2027890.0 1781760.0 1809860.0 1528060.0 True False 1893509.0497870808 2290380.0815638425 1817844.8920591741 1815675.8926766182 1678710.5773976992 1801222.933239195 1835793.5785478076 1734990.6879307698 1836325.7785812754 1805085.1818836948 1.0489859807120634 1.2688487527074588 1.0070687579198694 1.0058671529184409 0.9299896726457433 0.9978603510331466 1.0170121592999102 0.9611683178963455 1.017306993050034 1.0 20.783635488753248 -5.392969870728245 7.240743588365435 0.9887348251045572 1.1580601251327938 0.5942606976986629 0.055277482764874104 0.14528499861927235 7.822422483928655 0.013357496989704733 0.027989746660548168 4.046039602093199e-06 5.392969870728245 0.16932530002823654 S(ph)NSPLPVPPSK ddPTM_PC-9_Lapatinib_30min_R1 3 SNSPLPVPPSK 11 0 Q13247-3;Q13247 Q13247-3 SRSF6 Serine/arginine-rich splicing factor 6 1 S(0.861)NS(0.139)PLPVPPSK;S(0.981)NS(0.019)PLPVPPSK;S(0.969)NS(0.031)PLPVPPSK 164.92 0.00011428 987650000.0 3103970.0 2933800.0 2809740.0 2591250.0 3206600.0 2989040.0 2890870.0 2884120.0 3161000.0 2685440.0 True False 3059706.81860161 2927006.966352132 2578734.023110046 2781819.1691565937 3017994.0924181608 2861205.7269925578 3040545.1034644525 3018126.744197704 2804974.8931943323 3149614.7258761246 0.9714543158133397 0.9293222254470919 0.8187458618109943 0.8832252231684554 0.9582105606833067 0.9084303878458212 0.9653704875343659 0.9582526775106296 0.8905771458806206 1.0 21.586743932202623 -6.260825581944018 24.999698323248005 0.9437288670510438 0.8968793538894184 0.19176509580786594 0.04586043202694992 98.16646952098223 3998286.941780536 0.014347867567811751 0.017431340871144216 5.484972039795926e-07 6.260825581944018 -0.046849513161625334 S(ph)NSPPALGPEACPVSLPSPPEASTLK ddPTM_PC-9_AZD4547_30min_R2 1 SNSPPALGPEACPVSLPSPPEASTLK 26 0 Q9H0F6;Q9H0F6-2 Q9H0F6 SHARPIN Sharpin 1 S(0.58)NS(0.42)PPALGPEACPVSLPSPPEASTLK 121.39 2.3847e-12 3370800.0 23771.0 24944.0 33171.0 35197.0 32386.0 30013.0 29346.0 31663.0 26664.0 34511.0 True False 31329.683532484396 33006.660193494055 32731.130866453645 27082.87543822923 27889.762923052003 28136.282365455605 31957.7371492651 26770.210893356867 28073.404604365118 33302.78039433088 0.9407527888517571 0.9911082438964395 0.9828347807267603 0.8132316616674906 0.8374604940733317 0.844862862268558 0.9596116831946335 0.8038431198949968 0.8429747988592581 1.0 15.023355010109093 -5.747254964782773 24.98600161843581 0.8646555010127893 0.9735196131170655 0.3589649702080432 0.060620577514499466 231.1425599231349 407156.66550980794 0.01593363986803373 0.027429049852277825 1.7895549370536035e-06 5.747254964782773 0.10886411210427616 S(ph)NSPPALGPEACPVSLPSPPEASTLK ddPTM_PC-9_Lapatinib_30min_R1 1 SNSPPALGPEACPVSLPSPPEASTLK 26 0 Q9H0F6;Q9H0F6-2 Q9H0F6 SHARPIN Sharpin 1 S(0.537)NS(0.463)PPALGPEACPVSLPSPPEASTLK 74.465 4.8773e-05 2381000.0 9817.0 24823.0 23195.0 21671.0 25208.0 25846.0 23465.0 25510.0 26556.0 21904.0 True False 9677.007779782682 24765.523868620567 21287.996635289244 23264.757632336758 23725.31500083483 24740.626829968714 24679.902884873205 26695.287728833573 23564.98363292268 25690.07721475463 0.3766827051117179 0.9640112663576167 0.828646658292754 0.905593137687226 0.923520579658228 0.9630421358079603 0.9606784237572766 1.039128357056927 0.9172795953835653 1.0 14.648923605995893 -4.760050465822401 24.999901419869826 0.9414472108259578 0.37668201933448997 0.9085042135657192 0.05406504869426325 10.179641190898192 183163.311482684 0.014259805967197541 0.0867332148370697 1.7375989048097025e-05 4.760050465822401 -0.5647651914914679 S(ph)NSQSDSHDEEVSPTPPNPVVK ddPTM_PC-9_AZD4547_30min_R2 1 SNSQSDSHDEEVSPTPPNPVVK 22 0 C9J4C2;C9IZL8;C9JR00;C9JSK5;P31321 C9J4C2 PRKAR1B cAMP-dependent protein kinase type I-beta regulatory subunit 1 S(0.416)NS(0.416)QS(0.133)DS(0.035)HDEEVSPTPPNPVVK 79.586 0.0028518000000000003 0.0 18888.0 22456.0 35852.0 41629.0 34862.0 41522.0 28334.0 38913.0 32296.0 35253.0 True False 24893.99110519395 29714.46284898583 35376.57905471934 32032.077211638607 30022.013061923044 38925.62277607863 30855.67110976888 32899.889981783 34003.100626409236 34018.803200178096 0.7317715134982651 0.8734717289769403 1.0399125109296654 0.9415991804047625 0.8825123237070807 1.1442384538640926 0.907018125482067 0.9671089775906863 0.9995384148679053 1.0 15.054044766654824 -4.919768003375648 2.9758349044394863 0.9815003339664571 0.7228898186712924 0.5637766819014005 0.06958379389705643 0.21846051144766845 3.3689784615979868 0.017575187312791188 0.1161461490620704 1.2029068461931055e-05 4.919768003375648 -0.25861051529516466 S(ph)NSQSDSHDEEVSPTPPNPVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSQSDSHDEEVSPTPPNPVVK 22 0 C9J4C2;C9IZL8;C9JR00;C9JSK5;P31321 C9J4C2 PRKAR1B cAMP-dependent protein kinase type I-beta regulatory subunit 1 S(0.268)NS(0.268)QS(0.218)DS(0.177)HDEEVS(0.057)PT(0.011)PPNPVVK 46.398999999999994 0.033879 7135000.0 7771.5 13650.0 20667.0 15945.0 21135.0 16654.0 14409.0 20333.0 18059.0 11975.0 True False 9087.06145587836 15005.081790292721 21159.779660033957 15051.65334438748 16993.74846886697 15780.634922308567 13044.075207873866 19799.280294594297 18323.078710728576 14145.972705952161 0.6423779859305697 1.0607317080414749 1.4958165196466564 1.0640239209605034 1.2013135343967232 1.1155567206536878 0.9221052153158296 1.399640781595981 1.2952858804130751 1.0 13.788103762349703 -4.80882505795424 3.922367438994254 1.1899538772817895 0.606591925695292 0.48591029561400345 0.16740448971175004 0.18665834572976453 5.128809502561911 0.04201684386663715 0.2922831234837883 1.5530124668227915e-05 4.80882505795424 -0.5833619515864975 S(ph)NSRLEDQVIGVALQASK ddPTM_PC-9_AZD4547_30min_R2 2 SNSRLEDQVIGVALQASK 18 1 A0A3B3IRW6;Q2KHR3-2;Q2KHR3 A0A3B3IRW6 QSER1 Glutamine and serine-rich protein 1 1 S(0.5)NS(0.5)RLEDQVIGVALQASK;S(0.5)NS(0.5)RLEDQVIGVALQASK 131.35 1.9249e-05 16290000.0 70009.0 60461.0 76281.0 128917.0 99002.0 75696.0 89943.0 137818.0 106347.0 103908.0 True False 92270.40572233827 80003.8358707041 75269.46409887997 99197.17739779508 85257.28119891278 70962.71715375104 97947.75275732126 116521.39484258159 111968.28530829649 100270.21254713385 0.9202175140395247 0.7978823804038196 0.7506662466033786 0.9892985651263642 0.850275261547252 0.7077148372493348 0.9768379887624066 1.162073878997799 1.1166654828388216 1.0 16.613533560016897 -7.518288348220385 5.605513979300297 1.1002853733363398 0.8377016233070821 0.6565161253582623 0.08385379511137958 0.09740195999890894 10.939014380106562 0.03877343610071797 0.0236177616930179 3.0318775118850296e-08 7.518288348220385 -0.2625837500292577 S(ph)NSRLEDQVIGVALQASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SNSRLEDQVIGVALQASK 18 1 A0A3B3IRW6;Q2KHR3-2;Q2KHR3 A0A3B3IRW6 QSER1 Glutamine and serine-rich protein 1 1 S(0.5)NS(0.5)RLEDQVIGVALQASK;S(0.5)NS(0.5)RLEDQVIGVALQASK;S(0.5)NS(0.5)RLEDQVIGVALQASK;S(0.5)NS(0.5)RLEDQVIGVALQASK 167.59 2.7379e-18 9211300.0 64792.0 55275.9 58520.5 69923.4 83676.0 76045.0 89041.0 124888.0 87808.0 68839.0 True False 75760.00589966816 60763.3260463034 59915.85066023217 66005.81859272132 67280.2884731918 72057.06633042842 80606.39187898526 121609.82232977415 89092.02588358452 81318.96577077571 0.931640056923777 0.7472220713871945 0.7368004510672791 0.8116903352998912 0.8273628154942778 0.8861040674514356 0.9912372976582231 1.495466908329497 1.0955872967533764 1.0 16.31130424639391 -7.482766797879028 3.6982843119026034 1.2267674535583963 0.8183804945200469 0.6066472851380216 0.13275442861297 0.13538646071092522 3.8543243995105634 0.06023687182513269 0.03652106596610143 3.2902826100696346e-08 7.482766797879028 -0.40838695903834943 S(ph)NSRLEDQVIGVALQASK ddPTM_PC-9_Lapatinib_30min_R1 2 SNSRLEDQVIGVALQASK 18 1 A0A3B3IRW6;Q2KHR3-2;Q2KHR3 A0A3B3IRW6 QSER1 Glutamine and serine-rich protein 1 1 S(0.5)NS(0.5)RLEDQVIGVALQASK;S(0.5)NS(0.5)RLEDQVIGVALQASK 152.57 1.6484e-05 8969900.0 77828.0 70272.0 66977.0 65344.0 116085.0 99907.0 116368.0 85368.0 104529.0 115116.0 True False 76718.1584480927 70109.28950149864 61470.409598696555 70149.61574119393 109257.10853189106 95634.21050459199 122392.96564700316 89334.50893120581 92755.8432808321 135013.64721757176 0.5682252129998602 0.5192755765535239 0.45529034186920553 0.5195742592461727 0.8092301095742228 0.7083299538636963 0.9065229194924967 0.6616702146209342 0.6870108703260044 1.0 17.042745717105554 -6.256296498853586 23.780137652745 0.7797407707605535 0.5115472570776938 0.6517973474304659 0.0997987236886253 140.4686207573362 649510.1121980315 0.028952029668564878 0.03618901204251375 5.542471915330668e-07 6.256296498853586 -0.2681935136828597 S(ph)NSTAAQEDAK ddPTM_PC-9_AZD4547_30min_R2 2 SNSTAAQEDAK 11 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;H7C1R1;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 S(1)NSTAAQEDAK;S(0.999)NS(0.001)TAAQEDAK 97.69 0.0052862 1952000.0 17914.4 19724.1 16764.7 14531.3 14868.5 22682.7 16718.5 18627.0 18266.3 21532.0 True False 23610.806557331984 26099.52959920206 16542.38912413962 11181.333291346997 12804.265423991823 21264.347183251237 18206.414111973987 15748.625155877775 19231.81932660945 20778.171233830726 1.136327460757913 1.25610330695067 0.7961426892663939 0.5381288451960443 0.6162363992430718 1.0233983994043194 0.876227936861477 0.7579408687438327 0.925578055459302 1.0 14.342781062281196 -5.26640569494584 24.71882280686526 0.8004604164092997 1.1962153986294923 0.5062781649767706 0.1492208321391969 258.69030553536845 1287585.728766746 0.04132271062745859 0.09053280751656026 5.414948182326419e-06 5.26640569494584 0.3957549822201927 S(ph)NSTAAQEDAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSTAAQEDAK 11 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;H7C1R1;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 S(0.976)NS(0.014)T(0.009)AAQEDAK 69.456 0.034671 2345300.0 4416.5 8618.6 8236.7 4982.9 9331.9 9213.6 8159.0 7208.2 6873.8 5764.2 True False 5164.126220148851 9474.197649656904 8433.094165858702 4703.724267779763 7503.381184604666 8730.422596384187 7386.120453955365 7018.992387719206 6974.31632104801 6809.20383061791 0.7584038235025526 1.391381119633359 1.2384846122448105 0.6907891707734232 1.1019469193836369 1.2821502797621398 1.0847260028761838 1.0308095575224185 1.0242484282358626 1.0 12.733270404959836 -7.79438722725874 4.726042052001602 1.0183802410555234 1.0905054224897368 0.015570519726015197 0.20488018720343626 1.0911937063004569 56.66216808326277 0.11640536697414938 0.05619971918326391 1.6055091046489674e-08 7.79438722725874 0.07212518143421343 S(ph)NSTAAQEDAK ddPTM_PC-9_Lapatinib_30min_R1 2 SNSTAAQEDAK 11 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;H7C1R1;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 S(0.872)NS(0.06)T(0.068)AAQEDAK;S(0.513)NS(0.425)T(0.062)AAQEDAK 73.92699999999999 0.023518999999999998 5531800.0 8376.0 16500.800000000003 14192.900000000001 14803.2 20219.7 17646.2 20717.5 20879.1 16923.5 15474.5 True False 8256.556704029725 16462.59341140613 13026.014548178347 15891.87671002757 19030.41699945969 16891.51316130132 21790.15077849397 21849.21920890197 15017.397217644486 18149.24670652484 0.4549255865843406 0.9070675867493532 0.7177165399099106 0.875621835275085 1.0485513424983122 0.930700509747804 1.200609101349655 1.2038636954032342 0.827439147226181 1.0 14.14762204924077 -4.430586790063418 0.5255794856721853 1.0670701354508543 1.826710360020734e-11 0.5852036005835015 0.13664798418571575 4.311940196715892 0.6952727482025102 0.07864887994880093 3.056377332196493 3.7103357417518623e-05 4.430586790063418 -1.067070135432587 S(ph)NSTTQVSQPR ddPTM_PC-9_Lapatinib_30min_R1 1 SNSTTQVSQPR 11 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 S(0.958)NS(0.038)T(0.003)T(0.002)QVSQPR 163.33 0.001526 87555000.0 13845.0 10323.0 11747.0 10020.0 13631.0 14930.0 13287.0 10245.0 12725.0 8754.9 True False 13647.567761137961 10299.097727743234 10781.207004731312 10756.904225740138 12829.251379577106 14291.478703529861 13974.935846209692 10721.020101211292 11291.776499809512 10268.172799829035 1.3291135654987412 1.0030117264791953 1.0499635343993061 1.0475967278150247 1.2494191157155743 1.3918229642344755 1.3609953901868863 1.044102033556525 1.099687034873188 1.0 13.32589185943778 -3.2444072743651153 15.807853082288892 1.1631679936295642 44.38055623503066 0.0 0.1493480128398219 0.0 0.0 0.03647039820459479 0.0 0.0005696298320500671 3.2444072743651153 43.217388241401096 S(ph)NSVGIQDAFNDGSDSTFQKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSVGIQDAFNDGSDSTFQKR 21 1 O14497-2;O14497;H0Y488;A0A1B0GTU5;O14497-3;A0A087WUV6 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 S(0.544)NS(0.455)VGIQDAFNDGSDSTFQKR 61.89 0.0036271000000000003 18768000.0 10541.0 5660.6 8830.9 13539.0 17876.0 22203.0 17507.0 19935.0 22252.0 14552.0 True False 12325.383105759996 6222.546958397872 9041.462147374743 12780.453724030232 14373.32612393972 21038.635593852345 15848.610220296194 19411.727372878453 22577.3934033519 17190.162406431373 0.7170021326353897 0.3619830232709043 0.5259672325138739 0.7434748678842422 0.8361367265827699 1.2238764879836819 0.9219581435930319 1.1292346700352245 1.3133903490583076 1.0 14.069295554490283 -6.30012437155526 1.4709827990269346 1.1191985778236935 0.5164143419320861 0.7682304087780588 0.13828672256626298 0.1820456614379334 0.7898132285072638 0.051721639198460206 0.0690072462470756 5.010437261369202e-07 6.30012437155526 -0.6027842358916073 S(ph)NSVSLVPPGSSHTLPR ddPTM_PC-9_AZD4547_30min_R2 1 SNSVSLVPPGSSHTLPR 17 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 S(0.708)NS(0.292)VSLVPPGSSHTLPR 189.44 1.5223e-08 9681600.0 4882.0 5354.5 22727.0 44260.0 30098.0 20148.0 9643.8 28208.0 13635.0 22780.0 True False 6434.374448091739 7085.237412045533 22425.62513044199 34056.540810183425 25919.412229297206 18888.142374944164 10502.079517483911 23849.101755355157 14355.7182635958 21982.47913369237 0.2927046767090899 0.3223129369965395 1.0201590545840853 1.5492584163532874 1.1790941354549374 0.8592362244527033 0.47774773052723873 1.0849141086549166 0.6530527415168976 1.0 14.42406647885724 -5.258743894450232 23.063283460717628 0.9864513824814909 0.3075085385929732 0.4888214557299114 0.2741229220538336 69.4625276817686 594309.891056092 0.0775820251665322 0.1864904762937595 5.511326061504944e-06 5.258743894450232 -0.6789428438885177 S(ph)NSVSLVPPGSSHTLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSVSLVPPGSSHTLPR 17 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 S(0.821)NS(0.156)VS(0.023)LVPPGSSHTLPR 95.227 0.00094694 15615000.0 20934.0 33528.0 65447.0 52082.0 62486.0 49272.0 41170.0 32382.0 49136.0 29047.0 True False 24477.712734653225 36856.43826116735 67007.5046891297 49164.014392122204 50242.31685950419 46688.08958160129 37270.079555011966 31532.00681156508 49854.52104382075 34312.9911640745 0.713365751694689 1.0741249017006662 1.9528319279633704 1.4328105106615316 1.4642359979420159 1.360653443424759 1.0861798488157897 0.9189524358511452 1.4529342780240664 1.0 15.06646727488486 -7.258279754791174 22.77252227115613 1.1077626510049616 1.3599123465660212 0.09615931652748111 0.3216084693032925 190.97578624889263 1376446.5919737644 0.13384927940160102 0.09901058982646375 5.517219280278064e-08 7.258279754791174 0.2521496955610596 S(ph)NSWQGNLGGNK ddPTM_PC-9_AZD4547_30min_R2 1 SNSWQGNLGGNK 12 0 Q9P0K1-5;Q9P0K1;H7C3I4;H7C0Q9;Q9P0K1-4;Q9P0K1-3;Q9P0K1-2 Q9P0K1-5 ADAM22 Disintegrin and metalloproteinase domain-containing protein 22 1 S(0.587)NS(0.413)WQGNLGGNK 134.68 5.8129e-05 5755300.0 15834.0 21121.0 20396.0 20735.0 21067.0 14412.0 19550.0 23420.0 17824.0 14826.0 True False 20868.882632340166 27947.9502063337 20125.53571349034 15954.866102556553 18142.210692890047 13510.815361708133 21289.912126631654 19800.977138060753 18766.140251582805 14306.946252683185 1.458653877896992 1.9534532186484046 1.4066968141238325 1.1151831998784723 1.2680700949364077 0.9443535414955696 1.4880822050085534 1.3840114297170296 1.3116803488419706 1.0 13.804428148311706 -5.485881241549156 6.384773457711119 1.2354783014837818 1.7038202675078598 0.5044996559927368 0.19237504610586065 0.15826959392487155 18.997138793951777 0.05004153083007392 0.10188752266177242 3.2667715029639455e-06 5.485881241549156 0.46834196602407796 S(ph)NSWVNTGGPK ddPTM_PC-9_AZD4547_30min_R2 1 SNSWVNTGGPK 11 0 Q96N67-2;Q96N67-6;Q96N67;A0A1B0GWE0;A0A0U1RRC1 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 S(0.542)NS(0.458)WVNTGGPK 133.04 7.8018e-05 6763500.0 19788.0 18206.0 24711.0 36852.0 27283.0 27548.0 24981.0 28726.0 28857.0 24604.0 True False 26080.172384031022 24090.733462265576 24383.315994119435 28356.34075772434 23495.22638886026 25825.419205130143 27204.260605390562 24287.05675781099 30382.32210726688 23742.62144887475 1.098453784481623 1.0146619030312394 1.0269849960175754 1.1943222368593276 0.9895801286918883 1.0877240013593403 1.1457985237211399 1.0229307159745853 1.2796532250109562 1.0 14.535191612865376 -7.002231943346906 24.999999992428243 1.1144000506165213 1.0642641238051698 0.06022609735186646 0.08789786401865747 263.5794194573969 2952381.836537927 0.029772999701992948 0.025813429742096893 9.948739438185095e-08 7.002231943346906 -0.05013592681135148 S(ph)NTENLSQHFR ddPTM_PC-9_AZD4547_30min_R2 1 SNTENLSQHFR 11 0 Q9UHB6;Q9UHB6-4;F8VRN8;F8VTU2;F8VVQ7 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 S(0.5)NT(0.5)ENLSQHFR 111.81 0.0010009 9508800.0 17460.0 13379.0 41872.0 85426.0 61411.0 43399.0 31037.0 54073.0 38931.0 53756.0 True False 23011.91680943913 17703.500109395318 41316.749921321236 65732.35551854329 52885.14268102102 40685.25366935686 33799.23287336405 45717.26032392652 40988.8131807883 51874.01880205298 0.4436116063660062 0.34127874643663964 0.7964825335585156 1.2671537127164292 1.0194919133377038 0.7843088815734225 0.6515638011841567 0.8813132542974905 0.7901607418773212 1.0 15.662724522553242 -5.3396625154581985 4.708492401229988 0.9045936842843112 0.3924517588907508 0.6209926477256318 0.1596844478435457 0.14386125306939695 5.774831830918238 0.04682587283530472 0.1036285693303679 4.574435248930827e-06 5.3396625154581985 -0.5121419253935604 S(ph)NTLDIMDGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNTLDIMDGR 10 0 H0Y9X0;A0A286YEZ9;A0A2C9F2R7;O94915 H0Y9X0 FRYL Protein furry homolog-like 1 S(0.741)NT(0.259)LDIMDGR 71.806 0.028363 3977800.0 30950.0 36837.0 25495.0 26858.0 28059.0 21154.0 17893.0 22384.0 11843.0 12723.0 True False 36189.22370963587 40493.9339127482 26102.89749032594 25353.23333481086 22561.040373216838 20044.647000511322 16198.045505898204 21796.443717808444 12016.181470245214 15029.579184787417 2.407866731642476 2.6942826152933943 1.7367683532182108 1.6868891020230825 1.5011092523503644 1.333679855840544 1.0777444469166164 1.4502364603707791 0.7995021898156475 1.0 13.875516995156389 -5.260873346205452 0.5032545068455005 1.0361403568212895 3.287609390557943 0.8628711239373833 0.21089135917986707 0.9538689158039071 0.2626532773869361 0.13783148068027035 1.2015290463454595 5.484368828741782e-06 5.260873346205452 2.2514690337366536 up S(ph)NTLDIMDGR ddPTM_PC-9_Lapatinib_30min_R1 1 SNTLDIMDGR 10 0 H0Y9X0;A0A286YEZ9;A0A2C9F2R7;O94915 H0Y9X0 FRYL Protein furry homolog-like 1 S(1)NTLDIMDGR 120.6 0.0011447 0.0 9693.9 13920.0 14745.0 11804.0 9887.6 9421.4 8305.6 8390.8 11276.0 10441.0 True False 9555.663208356458 13887.76909524225 13532.723017345972 12672.10553698967 9306.030807769543 9018.468684356078 8735.623328387082 8780.667200121397 10005.978138455948 12245.712938242013 0.7803272260706989 1.134092328089145 1.105098828103733 1.0348197447464311 0.7599419367987823 0.7364592596477084 0.7133617595351833 0.7170400975757272 0.8171004978573669 1.0 13.57998914875757 -6.260910452596943 24.710429924479563 0.7699285815678509 1.0287289785641562 0.4508161143744782 0.118764175248011 32.15394031925422 1502163.020900245 0.03487560812262487 0.04232647683861104 5.483900260864996e-07 6.260910452596943 0.2588003969963053 S(ph)NTLPSDVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNTLPSDVGR 10 0 F5H4N6;Q9Y3R0-3;Q9Y3R0-2;Q9Y3R0;F5H4P8;H0YFK8 F5H4N6 GRIP1 Glutamate receptor-interacting protein 1 1 S(0.72)NT(0.172)LPS(0.108)DVGR 85.973 0.011563 24660000.0 67669.0 85560.0 60949.0 95167.0 96924.0 64744.0 86733.0 84302.0 67212.0 57326.0 True False 79124.02517632807 94053.83135365896 62402.25531036968 89835.10152557706 77932.43797475584 61348.71066470189 78517.0223474583 82089.16182535236 68194.84834738856 67718.75000763375 1.1684212299755774 1.3888890645952048 0.9214915411660027 1.3265912544967267 1.1508251107111507 0.9059338906548957 1.1594576441326412 1.2122072810868287 1.0070305246287201 1.0 16.04726772291839 -1.522878745372766 0.17053966440395898 1.0116295726542543 1.9705344757048506 0.15958262379114174 0.14218687585531856 116.93962612952103 1.2686079757926845 0.36319470874579607 28.626696491963077 0.029999999993615276 1.522878745372766 0.9589049030505963 S(ph)NTPESIAETPPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNTPESIAETPPAR 14 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 S(0.877)NT(0.118)PES(0.005)IAETPPAR 130.66 1.8785e-05 19863000.0 21121.0 21657.0 19863.0 22497.0 21381.0 19236.0 15242.0 18572.0 16701.0 15577.0 True False 24696.36814123488 23806.96383387321 20336.60925084698 21236.566026258082 17191.54653479274 18227.230296957332 13798.167417476134 18084.504678660564 16945.220529812163 18400.986792535852 1.3421219426804152 1.2937873442488548 1.105191231325501 1.1540993027000297 0.9342730761464538 0.9905572186134604 0.7498601880999773 0.9828008075086676 0.9208865111889432 1.0 14.167495515534144 -5.642699592136772 0.8519217017785753 0.9094957867486055 1.381109858200071 0.793620581255934 0.07726624066903663 0.37769400537758885 0.46056800818633076 0.03264792921368043 0.13298782673492418 2.276671693442873e-06 5.642699592136772 0.4716140714514654 S(ph)NTPESIAETPPAR ddPTM_PC-9_Lapatinib_30min_R1 2 SNTPESIAETPPAR 14 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 S(0.679)NT(0.238)PES(0.076)IAET(0.007)PPAR;S(0.989)NT(0.011)PESIAETPPAR 193.98 1.5460000000000002e-07 23774000.0 61272.0 56219.0 57361.0 50683.0 45527.0 45515.0 40170.0 40367.0 42321.0 29703.0 True False 60398.25004409136 56088.82835958508 52644.99999986318 54410.39689353164 42849.19136952586 43568.429550647124 42249.80604668046 42242.59818697865 37554.36332011301 34837.123973240356 1.7337323853279456 1.6100303917932182 1.5111752635005604 1.5618509993915173 1.2299864765656277 1.2506322159117842 1.2127811147422518 1.2125742130557822 1.0779983832465578 1.0 15.088337904725849 -5.2397714148205115 0.29138925776667657 0.9929485116244787 2.1764505351240753 0.9359550281960471 0.0589833055891384 1.4620510818793324 0.12637481634134104 0.07485121417593721 0.6058184807628345 5.757428922889516e-06 5.2397714148205115 1.1835020234995965 S(ph)NVCINGNHVYLEQPEAK ddPTM_PC-9_AZD4547_30min_R2 2 SNVCINGNHVYLEQPEAK 18 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 S(1)NVCINGNHVYLEQPEAK;S(1)NVCINGNHVYLEQPEAK 121.91 3.5861999999999996e-05 37339000.0 52111.0 72570.0 108441.0 125236.0 85931.0 129846.0 122251.0 115391.0 113344.0 123086.0 True False 68681.21402386497 96026.83331630306 107003.00148590944 96364.77507691206 74000.9639270297 121726.70909355747 133131.1021684319 97559.97237139056 119335.13244363786 118776.79660446278 0.5782376355255604 0.8084645828265675 0.9008746198320104 0.8113097661474679 0.6230254228311902 1.024835763999581 1.120851091916296 0.8213723147987723 1.0047007147451061 1.0 16.85789350339349 -6.778257416672697 24.964065249713215 0.9910939987180997 0.7603547152920299 0.5559113323875706 0.11123316818675238 207.19361958500457 307548.42563065334 0.040519830681316586 0.03582764317989534 1.666259288271006e-07 6.778257416672697 -0.23073928342606975 S(ph)NVCINGNHVYLEQPEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNVCINGNHVYLEQPEAK 18 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 S(1)NVCINGNHVYLEQPEAK;S(1)NVCINGNHVYLEQPEAK 121.35 3.9138000000000004e-05 22897000.0 62076.0 62681.0 72598.0 92097.0 104440.0 82532.0 111553.0 77317.0 75167.0 84623.0 True False 72584.24074311327 68903.5554357025 74329.01164944834 86937.10367250259 83975.73172881304 78203.8766307175 100985.89226621925 75287.51067413297 76266.17517300702 99964.48002470042 0.7261003180847666 0.6892803865800831 0.7435542267721719 0.8696799468273244 0.840055704867002 0.7823166449862385 1.010217751758089 0.7531426228149242 0.7629327452527365 1.0 16.609127938482928 -5.65734898439777 4.272624801439547 0.8516768895483384 0.7095900424574094 0.3687122830219072 0.08419715996496166 0.23920980963122607 7.74779995039751 0.022956336314805356 0.0410099349220527 2.20115697669306e-06 5.65734898439777 -0.142086847090929 S(ph)NVCINGNHVYLEQPEAK ddPTM_PC-9_Lapatinib_30min_R1 2 SNVCINGNHVYLEQPEAK 18 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 S(1)NVCINGNHVYLEQPEAK;S(1)NVCINGNHVYLEQPEAK 130.98 2.3247e-05 38347000.0 230250.0 196877.0 164179.0 155175.0 143614.0 169379.0 138975.0 115442.0 133144.0 106994.0 True False 226966.59277732146 196421.14340258643 150680.83636926694 166587.0871486254 135166.90687598745 162135.05501173396 146170.4454901024 120805.85676174099 118147.92065152364 125487.77033945678 1.8086749980763421 1.565261243157384 1.2007611256591812 1.3275165117524275 1.077132110247458 1.2920386948715612 1.164818253561259 0.9626902799766801 0.9415094421705149 1.0 16.937187244745616 -1.5228787452831016 0.36421078297300735 1.0073370823066234 11.426505444207587 0.8595049960985495 0.09892251723282364 23.752236730049237 0.3301757927742762 0.08438291668448923 172.23002908699732 0.029999999999809065 1.5228787452831016 10.419168361900963 S(ph)PAAGSSQSSGWPNDVDAGPASLKK ddPTM_PC-9_AZD4547_30min_R2 3 SPAAGSSQSSGWPNDVDAGPASLKK 25 1 K7EN08;Q14938-6;Q14938-5;Q14938-3;Q14938-4;Q14938 K7EN08 NFIX Nuclear factor 1;Nuclear factor 1 X-type 1 S(0.874)PAAGS(0.078)S(0.018)QS(0.026)S(0.005)GWPNDVDAGPASLKK;S(0.404)PAAGS(0.131)S(0.155)QS(0.155)S(0.155)GWPNDVDAGPASLKK;S(0.956)PAAGS(0.022)S(0.007)QS(0.004)S(0.01)GWPNDVDAGPASLKK 128.91 7.9614e-08 17557900.0 58273.0 46309.2 81043.0 100134.0 78716.0 72389.0 62135.0 91769.0 61800.0 61346.0 True False 76802.60184630274 61277.74327423646 79968.3168674444 77049.6533548782 67787.6421370642 67862.50438653133 67664.89462855535 77588.20969183173 65066.62183279948 59198.29521226915 1.2973786081323675 1.0351268234078528 1.3508550639963457 1.3015518956854903 1.1450944979749158 1.14635909941654 1.1430210006204953 1.3106493930884546 1.0991299935156593 1.0 15.853268009386465 -6.287715148982071 24.330464191363852 1.156639562182971 1.2386228000593567 0.180440037981492 0.10649215316215825 1200.257777067629 1111393.0022411952 0.0328387055555968 0.03724921923388919 5.155666906567452e-07 6.287715148982071 0.08198323787638562 S(ph)PAAGSSQSSGWPNDVDAGPASLKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPAAGSSQSSGWPNDVDAGPASLKK 25 1 K7EN08;Q14938-6;Q14938-5;Q14938-3;Q14938-4;Q14938 K7EN08 NFIX Nuclear factor 1;Nuclear factor 1 X-type 1 S(0.99)PAAGS(0.008)S(0.002)QS(0.001)SGWPNDVDAGPASLKK;S(0.999)PAAGS(0.001)SQSSGWPNDVDAGPASLKK;S(0.951)PAAGS(0.011)S(0.011)QS(0.017)S(0.011)GWPNDVDAGPASLKK;S(0.69)PAAGS(0.231)S(0.068)QS(0.005)S(0.005)GWPNDVDAGPASLKK 135.13 3.0129000000000005e-10 19307400.0 84448.0 89214.9 112465.0 114071.0 128460.0 105483.0 122449.0 103449.0 112387.0 87638.0 True False 98743.37847597184 98071.56567126646 115146.59212588772 107679.9716931717 103289.18515782598 99951.28578779125 110849.74426601073 100733.57336327588 114030.44725968497 103526.07565797382 0.9538020044553518 0.9473126943908529 1.112247242002154 1.0401241523818732 0.9977117793885043 0.9654696669659067 1.0707422604545798 0.9730260972711482 1.1014659498580353 1.0 16.6596346671312 -5.150190889518345 20.135029482234245 1.0296629348043091 0.9505345482257498 0.31728006966456046 0.04798292028215393 6.832278004229425 1225.983356792514 0.011923718376091701 0.031547663398647806 7.076346827233368e-06 5.150190889518345 -0.07912838657855936 S(ph)PAAGSSQSSGWPNDVDAGPASLKK ddPTM_PC-9_Lapatinib_30min_R1 1 SPAAGSSQSSGWPNDVDAGPASLKK 25 1 K7EN08;Q14938-6;Q14938-5;Q14938-3;Q14938-4;Q14938 K7EN08 NFIX Nuclear factor 1;Nuclear factor 1 X-type 1 S(0.986)PAAGS(0.009)S(0.002)QS(0.001)S(0.001)GWPNDVDAGPASLKK 140.69 6.7553e-07 10664000.0 40063.0 37651.0 36090.0 28681.0 43131.0 36448.0 33388.0 34376.0 39906.0 31911.0 True False 39491.69427334562 37563.821422770554 33122.81951142872 30790.296417011246 40594.11937880862 34889.2040044378 35116.66727126134 35973.23445575784 35411.366051190416 37426.77383126526 1.0551722799135679 1.003661752736775 0.8850033310581225 0.8226810185624365 1.0846278004570473 0.9321990765683458 0.9382766313116169 0.9611631132819368 0.946150641004723 1.0 15.191783073573287 S(ph)PAAPGQSPTGSVCYER ddPTM_PC-9_AZD4547_30min_R2 1 SPAAPGQSPTGSVCYER 17 0 O75534;O75534-4 O75534 CSDE1 Cold shock domain-containing protein E1 1 S(0.993)PAAPGQS(0.002)PT(0.003)GS(0.001)VCYER 79.346 0.006448399999999999 7945800.0 4095.6 4395.1 5234.3 5689.1 6696.0 7427.7 5714.9 6089.5 3891.3 3932.9 True False 5397.915606227884 5815.730124135091 5164.889761969138 4377.56589071881 5766.375981373317 6963.244744807066 6223.515028771724 5148.507697789111 4096.986173753601 3795.2103680815935 1.4222968116933206 1.5323867612310595 1.3608968307545732 1.1534448597460978 1.5193824378931884 1.8347453947136148 1.6398340079149796 1.3565803205769549 1.0795149086358946 1.0 11.889964140942228 -8.207165585515764 2.973387436557235 1.0143068872263958 1.4919982567546939 0.5336183530185016 0.1679341782785441 0.23294477150085915 3.7903108817534976 0.1665827788664349 0.05018771850958404 6.206323576725947e-09 8.207165585515764 0.47769136952829805 S(ph)PAAPGQSPTGSVCYER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPAAPGQSPTGSVCYER 17 0 O75534;O75534-4 O75534 CSDE1 Cold shock domain-containing protein E1 1 S(0.998)PAAPGQS(0.001)PT(0.001)GSVCYER 148.36 7.271e-05 7415200.0 6271.8 9045.8 6967.4 6021.3 8435.7 7173.8 10682.0 6214.8 10378.0 8471.6 True False 7333.491866303529 9943.807242390469 7133.529240011643 5683.946082317992 6782.78514117914 6797.593299246859 9670.123629017187 6051.6680851249 10529.758616752928 10007.434018851296 0.7328044184442501 0.9936420488667752 0.712823010031743 0.5679723764964102 0.6777746551615738 0.679254370944843 0.9662940181070685 0.6047172605610186 1.052193658925726 1.0 13.288784483309891 -8.276933780290578 24.770799172743782 1.0260969189077882 0.746786898627153 0.4267638479815712 0.13164868224707485 822.6233029237894 1315108.059194717 0.1283637093523949 0.033642718169931855 5.28525833409197e-09 8.276933780290578 -0.27931002028063523 S(ph)PAAPGQSPTGSVCYER ddPTM_PC-9_Lapatinib_30min_R1 2 SPAAPGQSPTGSVCYER 17 0 O75534;O75534-4 O75534 CSDE1 Cold shock domain-containing protein E1 1 S(0.932)PAAPGQS(0.064)PT(0.003)GSVCYER;S(0.986)PAAPGQS(0.004)PT(0.006)GS(0.004)VCYER 159.44 2.9156e-05 12813000.0 16848.3 17526.4 18223.9 16045.1 18400.8 18178.2 17417.699999999997 16197.5 20940.6 13950.699999999999 True False 16608.04015240018 17485.818697618797 16725.60128828834 17225.110178884534 17318.501121364705 17400.760761453883 18319.503280539353 16950.0949818809 18582.049113706173 16362.059906860723 1.0150335744362062 1.0686807649620496 1.0222185582681544 1.0527470426667933 1.0584548168108674 1.0634822791571388 1.1196330648354282 1.0359389391291502 1.1356790782751378 1.0 13.99806676782519 -6.442929799570973 1.6931324894733817 1.0763767799342874 1.0391171384956928 0.12712036542361083 0.03849315394622169 0.6849205170598425 3.9369219783170015 0.013572642389345503 0.01578156387210193 3.6063693255193283e-07 6.442929799570973 -0.037259641438594615 S(ph)PACSSLTPSLCK ddPTM_PC-9_AZD4547_30min_R2 1 SPACSSLTPSLCK 13 0 Q96R06;F5GZT2;J3KSV2;J3QRV8 Q96R06 SPAG5 Sperm-associated antigen 5 1 S(1)PACSSLTPSLCK 98.94200000000001 0.0026318 7958400.0 15339.0 12489.0 14233.0 19289.0 22099.0 20462.0 20410.0 23081.0 20895.0 18623.0 True False 20216.482928979774 16525.825014293896 14044.261120323004 14842.219062079255 19030.935306506723 19182.507905306105 22226.450460590917 19514.36179861572 21999.467042012042 17971.01443840003 1.1249494567085585 0.9195822011573209 0.7814951776074235 0.82589767611364 1.0589794678391597 1.0674137495720544 1.2367944245316487 1.0858798130459404 1.2241638955563972 1.0 14.133384228794704 -6.527056541161208 2.8308308219027323 1.135983722635467 0.9053193178641746 0.45392063578948283 0.10741364600123052 0.2367053534361471 3.852904437101674 0.03809830206964752 0.04054529689172698 2.971279173239457e-07 6.527056541161208 -0.23066440477129235 S(ph)PAFALK ddPTM_PC-9_AZD4547_30min_R2 4 SPAFALK 7 0 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 S(1)PAFALK;S(1)PAFALK;S(1)PAFALK;S(1)PAFALK 80.438 0.025405 131663000.0 320934.0 321183.0 353261.0 398903.0 413913.0 432920.0 347727.0 481426.0 366508.0 419151.0 True False 422984.33615810674 424999.1236741098 348576.52832336293 306942.0763399139 356448.3246084498 405849.4439627167 378674.0293635427 407032.67376891675 385880.8646390888 404476.65106963424 1.0457571161141914 1.0507383369354055 0.8617964161875746 0.7588622866813419 0.8812580989924288 1.0033939978721937 0.9362073888867087 1.0063193331247258 0.9540250682422111 1.0 18.625696898085152 -6.765779501257429 24.999702774622026 0.9776477566032724 0.9148129885081235 0.11605639837045889 0.08254651321506962 287.7334870227064 1657373.8681010911 0.03257724902270225 0.029724573108165793 1.714827733918897e-07 6.765779501257429 -0.06283476809514887 S(ph)PAFALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPAFALK 7 0 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 S(1)PAFALK;S(1)PAFALK;S(1)PAFALK 83.61399999999999 0.020759 98703000.0 429030.0 440730.0 499520.0 468150.0 519280.0 410540.0 472200.0 378167.0 378662.0 366940.0 True False 501656.3052712477 484482.7617169021 511430.45124014834 441921.0732627791 417530.81168267113 389010.5596856342 427469.79756805144 368240.5169510569 384199.21539187676 433463.31730455835 1.1573212432155495 1.1177018732048707 1.1798702008290336 1.0195120454732232 0.9632437048630512 0.8974474751511882 0.9861729482121419 0.8495309804781592 0.8863477024560585 1.0 18.725550382112182 -6.042144936565386 2.0421012404063834 0.9204580208391436 1.1503963552828493 0.8149063309150997 0.04685863310675939 0.12719700936996528 1.0577379721123954 0.014916505494012865 0.02282718092058336 9.075176148934173e-07 6.042144936565386 0.2299383344437057 S(ph)PAFALK ddPTM_PC-9_Lapatinib_30min_R1 4 SPAFALK 7 0 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 S(1)PAFALK;S(1)PAFALK;S(1)PAFALK;S(1)PAFALK 82.75 0.022022999999999997 111989000.0 502894.0 432184.0 542444.0 418113.0 489459.0 473111.0 351503.0 341751.0 477085.0 353113.0 True False 495722.6393405357 431183.30450130533 497846.34821439337 448862.42480408034 460669.9839334186 452877.1454056071 369702.1054226117 357629.9990833634 423350.66337222914 414148.111556503 1.1969694549069634 1.0411330933775806 1.2020973519433065 1.0838210105971742 1.1123314849899262 1.0935149352813607 0.8926808914645323 0.8635316426755486 1.0222204365031147 1.0 18.65978728466 -7.175225984595164 4.9800800632994155 0.9336451122137953 1.1218871364659653 0.6567796989012256 0.06269401516369777 0.12835740629789807 5.420457271098758 0.02350506851458976 0.017965687905621756 6.679962361054612e-08 7.175225984595164 0.18824202425216996 S(ph)PAFTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPAFTSR 7 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 S(1)PAFTSR 74.376 0.034272000000000004 14098000.0 6964.8 5905.5 5274.4 4229.5 4806.9 11727.0 3812.6 0.0 4350.6 5600.7 True False 8143.80307892963 6491.759011910152 5400.16169927339 3992.534827224009 3865.022451620375 11112.015475796357 3451.4429271663494 0.0 4414.219294473431 6616.062574883191 1.23091385348232 0.9812118519790098 0.8162198646328147 0.6034608624140014 0.5841877110251807 1.679551145417113 0.5216762822451518 0.0 0.6671973314205489 1.0 12.691757164281121 -7.491103905694796 24.981173153532623 0.45232651378219846 0.953039341474342 0.22595704449865728 0.3786183480038544 848.63968762765 667196.8993989542 0.1583627338112244 0.10664956497790423 3.2277217913872924e-08 7.491103905694796 0.5007128276921435 S(ph)PAFTSR ddPTM_PC-9_Lapatinib_30min_R1 1 SPAFTSR 7 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 S(0.999)PAFT(0.001)SR 72.87899999999999 0.037712999999999997 14561000.0 12269.0 11280.0 18716.0 10300.0 10513.0 11100.0 9941.7 9352.9 13499.0 9316.4 True False 12094.041810140961 11253.88185304113 17177.242725849257 11057.496359792756 9894.646009353248 10625.278875363798 10456.432580888299 9787.469878440123 11978.60046922818 10926.727326677308 1.1068311168169893 1.0299407605390758 1.5720391121970698 1.0119678133448227 0.9055452482277779 0.9724118263134899 0.9569592310919302 0.8957366268804274 1.096266074104618 1.0 13.415573742446899 -5.973572804796324 24.998907532706486 0.9646988546412779 1.2283651547379741 0.416491286237593 0.14113291091847127 209.1756632703456 197869.07500954473 0.039250734537364655 0.05821651225093989 1.0627404113482948e-06 5.973572804796324 0.2636663000966962 S(ph)PAGGESATVAAK ddPTM_PC-9_AZD4547_30min_R2 3 SPAGGESATVAAK 13 0 Q147X3 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 S(1)PAGGESATVAAK;S(1)PAGGESATVAAK;S(1)PAGGESATVAAK 135.81 5.2592e-05 42137400.0 38246.0 44686.0 49519.0 43493.0 40960.0 48065.0 54720.0 61111.0 45669.0 41548.0 True False 50407.43243378057 59129.8756176425 48862.34570486021 33466.360810151535 35273.411021064974 45059.487951741685 59589.97399331381 51667.69914107729 48082.97010488862 40093.41716622698 1.2572495934879226 1.474802593465419 1.2187124260892335 0.8347096150822035 0.8797806102388753 1.123862497549795 1.4862782522690512 1.2886828510242325 1.1992734344777103 1.0 15.291077763330835 -1.5247127902902164 0.011400387050471156 1.1487338323223387e-07 2.541800362018934 0.040900486104602396 0.2066234175734329 60263.573610860585 53.312409142570324 5017.061368235854 7025.52336004118 0.029873575794435298 1.5247127902902164 2.5418002471455505 S(ph)PAGGESATVAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPAGGESATVAAK 13 0 Q147X3 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 S(1)PAGGESATVAAK;S(1)PAGGESATVAAK;S(1)PAGGESATVAAK;S(1)PAGGESATVAAK 135.91 5.3018e-05 58734900.0 70698.0 112579.0 92689.0 68134.0 73148.0 41607.8 81266.0 50642.8 55113.0 57962.0 True False 82665.77505085095 123755.09911130877 94899.05728498979 64316.67287340839 58815.17449731159 39425.81372165428 73567.8961651105 49313.48016048198 55918.92336144766 68470.05177306045 1.2073274798278422 1.8074339934996255 1.3859936545619473 0.9393402109082937 0.8589912373989533 0.5758110692296332 1.074453637174783 0.7202197001972237 0.8166917055472268 1.0 16.063185482861773 -5.753257900909296 3.1890570803425873 0.8307025088247246 1.5272955538237267 0.6958871703716815 0.18700470759870857 0.11917024535812595 2.503682492014545 0.050973165692115636 0.08886171716137055 1.7649893902551597e-06 5.753257900909296 0.6965930449990021 S(ph)PAGGESATVAAK ddPTM_PC-9_Lapatinib_30min_R1 4 SPAGGESATVAAK 13 0 Q147X3 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 S(1)PAGGESATVAAK;S(1)PAGGESATVAAK;S(1)PAGGESATVAAK;S(1)PAGGESATVAAK 195.94 1.0637999999999999e-06 67133000.0 72387.0 109899.0 86545.0 90178.0 118906.0 112004.0 102316.0 110462.0 112522.0 86019.0 True False 71354.74810584985 109644.53561767461 79429.60417336106 96809.99094498935 111912.18285819056 107213.85001407638 107613.42184396705 115594.46778135712 99848.58745081071 100887.26953688721 0.707272071425826 1.0868024887677776 0.7873104757218092 0.9595857969928793 1.109279529240033 1.0627094033392983 1.0666699806423106 1.1457785339218893 0.9897045277283798 1.0 16.622384613849164 -6.04659508753732 4.845883006907138 1.0685049538606803 0.880976448641368 0.4469154183252608 0.10006812971188249 0.18614312607246816 9.901312654931546 0.027697673437515922 0.037468627407474 8.982658982839014e-07 6.04659508753732 -0.1875285052193123 S(ph)PAGPAATPAQAQAASTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPAGPAATPAQAQAASTPR 19 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 S(1)PAGPAATPAQAQAASTPR;S(1)PAGPAATPAQAQAASTPR 174.15 1.4573e-28 5089100.0 2883.38 3382.4 3341.5 4386.799999999999 3101.2 3223.0 1774.4299999999998 830.6 1843.42 3105.5 True False 3371.479284649107 3718.1823184971486 3421.174032709318 4141.021818197491 2493.542122150473 3053.980206232767 1606.3431446392967 808.7976300934456 1870.3765300919915 3668.5025668755243 0.9190341898876213 1.0135422425679088 0.9325805203465193 1.1288043943565815 0.6797166082602011 0.8324868663875169 0.43787434119404867 0.22047078211050597 0.5098474093981614 1.0 11.840975579285503 -6.833827971978644 1.5682325494413152 0.48809809523844766 0.9833982978161766 0.43297145203348963 0.21051476334750388 0.30777141160641 1.5668256078114158 0.09280675316520313 0.07946519081958109 1.4661284728657617e-07 6.833827971978644 0.49530020257772894 S(ph)PAGPAATPAQAQAASTPR ddPTM_PC-9_Lapatinib_30min_R1 2 SPAGPAATPAQAQAASTPR 19 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 S(1)PAGPAATPAQAQAASTPR;S(1)PAGPAATPAQAQAASTPR 175.52 1.2331000000000001e-08 11864600.0 642.7 2200.63 1769.93 772.15 1533.92 1108.9 1875.8400000000001 2520.4 1788.15 0.0 True False 633.534980143255 2195.5345764413055 1624.413187527376 828.9364868168906 1443.6978414027515 1061.4749319721545 1972.961816644389 2637.5069851725657 1586.749716945727 0.0 0.0 S(ph)PAGSQQQFGYSPGQQQTHPQGSPR ddPTM_PC-9_AZD4547_30min_R2 2 SPAGSQQQFGYSPGQQQTHPQGSPR 25 0 Q8TAP9 Q8TAP9 MPLKIP M-phase-specific PLK1-interacting protein 1 S(0.51)PAGS(0.169)QQQFGY(0.137)S(0.182)PGQQQT(0.002)HPQGSPR;S(0.916)PAGS(0.084)QQQFGYSPGQQQTHPQGSPR 117.99 3.7069e-06 4492700.0 2812.0 2742.9 3327.5 10583.7 8418.2 3030.3 2426.5 5441.2 3115.7 6324.5 True False 3706.157506766483 3629.4887846670476 3283.3751758501244 8143.791481534978 7249.4782387092155 2840.8148619611534 2642.4537992466353 4600.387566337153 3280.3895411723825 6103.081180027976 0.6072600703550685 0.594697772748684 0.5379864824008573 1.3343737763451553 1.1878390643782957 0.46547223904829843 0.4329704490731553 0.7537811526072581 0.5374972811941763 1.0 12.575322065183968 -10.316240877252188 16.129450254673827 1.0000000329481697 0.7253751706192515 0.07843117942982736 0.2898360727502484 0.0 0.0 0.30735768559631493 0.07454518838582298 4.8279095241398943e-11 10.316240877252188 -0.27462486232891825 S(ph)PALKSPLQSVVVR ddPTM_PC-9_AZD4547_30min_R2 1 SPALKSPLQSVVVR 14 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.97)PALKS(0.029)PLQSVVVR 51.93899999999999 0.043879 14662000.0 24766.0 14299.0 33545.0 58527.0 51474.0 33153.0 28049.0 31908.0 22411.0 30996.0 True False 32641.072835198724 18920.87211781475 33100.171382086366 45034.50438313612 44327.72360591552 31079.93766907506 30545.306661887036 26977.35177289678 23595.5997070367 29910.839474448123 1.091279061662009 0.6325757635113601 1.1066279637641996 1.505624889652718 1.4819953028661492 1.0390861044079243 1.021211948530596 0.9019255977734317 0.7888645093760631 1.0 14.868380781100921 -7.448530640851839 2.2389262221233417 0.886420950461738 1.1513556076484788 0.18623293783246653 0.2328816799186213 0.6181762604706152 6.08674170517007 0.14503422357981743 0.08145936554218694 3.5601587110205036e-08 7.448530640851839 0.2649346571867408 S(ph)PALKSPLQSVVVR ddPTM_PC-9_Lapatinib_30min_R1 1 SPALKSPLQSVVVR 14 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.999)PALKS(0.001)PLQSVVVR 52.821000000000005 0.04135 12824000.0 75231.0 28062.0 29764.0 28530.0 23843.0 23401.0 15067.0 14077.0 32320.0 21912.0 True False 74158.19214432417 27997.024163124148 27316.918812362554 30628.191373290007 22440.60161714159 22400.193780395326 15847.095536602808 14731.068810615057 28679.78125531185 25699.460004095283 2.8855933989471705 1.0894012620756521 1.0629374628108732 1.1917834603687905 0.8731935073174929 0.8716211849130601 0.6166314597301861 0.5732053828472512 1.115968244108695 1.0 14.649450425443371 -2.9955403946678887 1.3016766157302222 0.8682404065908155 199.99999999679582 0.8954648159581543 0.1997108312236615 44.076141668569356 0.9944391031165798 0.061534282982141565 25382.524383755983 0.0010103215239704428 2.9955403946678887 199.131759590205 up S(ph)PALSDANK ddPTM_PC-9_AZD4547_30min_R2 4 SPALSDANK 9 0 P52701-2;P52701;P52701-3;A0A087WWJ1;F8WAX8;F8W7G9 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 S(1)PALSDANK;S(1)PALSDANK;S(1)PALSDANK;S(1)PALSDANK 109.16 0.0023875 228111000.0 276136.0 299202.0 326938.0 357736.0 375056.0 377777.0 354370.0 422960.0 344017.0 350174.0 True False 363941.50401439186 395913.19528599305 322602.5885025053 275265.4921661046 322985.94833780616 354154.5444698864 385908.2434943457 357601.2506538939 362201.0362953745 337914.51484467083 1.077022406633479 1.1716371386650333 0.9546869824481972 0.8146009717654061 0.9558214700729062 1.0480595798990187 1.1420292012958844 1.058259515186178 1.0718717911891635 1.0 18.366298796068087 -6.953348601266576 7.081337676187337 1.076003661439713 0.9928963473276661 0.12522396963672033 0.09172010304424712 0.45980955306922966 55.34945250772542 0.03684525744806653 0.032330736985665395 1.1134004659843101e-07 6.953348601266576 -0.08310731411204697 S(ph)PALSDANK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SPALSDANK 9 0 P52701-2;P52701;P52701-3;A0A087WWJ1;F8WAX8;F8W7G9 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 S(1)PALSDANK;S(1)PALSDANK;S(1)PALSDANK;S(1)PALSDANK;S(1)PALSDANK;S(1)PALSDANK 126.39 0.001396 223448800.0 403788.0 514327.0 452996.0 496889.0 554828.0 491597.0 571642.0 423286.0 446116.0 400584.0 True False 472141.3332234728 565385.9854912721 463797.1426368974 469049.92026587273 446113.4362661228 465816.7879129407 517491.9314303176 412175.19100859016 452639.6025314467 473206.70817880105 0.9977486055524689 1.1947970637762833 0.9801153166697116 0.9912157037483127 0.9427453765037476 0.9843833146526992 1.0935853665768056 0.8710256720470029 0.9565367411495294 1.0 18.852110999905918 -5.372378219603075 10.220162941303343 0.9762478576416812 1.0961329024827158 0.3263755077314614 0.06828115242791773 0.4250532880094474 36.16639762538481 0.017367101225854963 0.03618805114769115 4.2424993103990684e-06 5.372378219603075 0.11988504484103457 S(ph)PALSDANK ddPTM_PC-9_Lapatinib_30min_R1 4 SPALSDANK 9 0 P52701-2;P52701;P52701-3;A0A087WWJ1;F8WAX8;F8W7G9 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 S(1)PALSDANK;S(1)PALSDANK;S(1)PALSDANK;S(1)PALSDANK 135.8 0.0010382 244496000.0 506375.0 526699.0 489443.0 498890.0 537420.0 508360.0 494296.0 466043.0 460481.0 403305.0 True False 499153.9996421983 525479.4608257894 449202.8858446167 535580.0348482525 505810.01220837253 486618.6278450399 519888.2282710969 487697.0591536164 408616.78070010094 473015.7318798665 1.0552587704820149 1.1109132855632955 0.9496573910118963 1.1322668544653727 1.069330210642624 1.0287578087754345 1.0990928910650581 1.0310377145711478 0.8638545256754352 1.0 18.85152864093518 -8.08134583675141 6.248717516726743 0.9338838151021456 1.0627842939519372 0.45836608927663947 0.056417147095805385 0.19931619440186238 12.29448468893614 0.036362496502944416 0.013542301158357787 8.291902049998392e-09 8.08134583675141 0.1289004788497916 S(ph)PAPAQTR ddPTM_PC-9_Lapatinib_30min_R1 1 SPAPAQTR 8 0 E7ERS3;Q86VM9 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 S(1)PAPAQTR 72.243 0.033212 4826600.0 929.07 1101.6 2269.5 2239.5 2651.8 2246.7 2302.0 1060.6 3376.6 2152.8 True False 915.8212914294285 1099.0493128821022 2082.910470523344 2404.2003007529966 2495.826337639393 2150.6138783135007 2421.186296227493 1109.8793479106582 2996.2917508256814 2524.9086115743125 0.36271462944490585 0.4352828089872255 0.8249448954212338 0.9521929980879376 0.9884818508671542 0.8517590967272933 0.95892036849518 0.43957208701452144 1.1866931488492392 1.0 11.302015455491048 -5.263442471239404 3.372567257215091 0.8909056745905076 0.3750188151714068 0.5581359885880357 0.17971314211320127 0.17134546177733656 4.113830709267491 0.046231745786381506 0.12860047393485058 5.452021110306964e-06 5.263442471239404 -0.5158868594191008 S(ph)PAPGYKR ddPTM_PC-9_AZD4547_30min_R2 1 SPAPGYKR 8 1 C9JG35;C9J092;C9JCJ0;Q96K58;Q96K58-2 C9JG35 ZNF668 Zinc finger protein 668 1 S(1)PAPGYKR 56.547 0.039007 2517500.0 17210.0 16812.0 24458.0 26440.0 23528.0 22038.0 14021.0 22888.0 17015.0 23614.0 True False 22682.42200976217 22246.150223421322 24133.670939426695 20344.666493927918 20261.54332284222 20659.960376167342 15268.841837723907 19351.18551391692 17914.37816318904 22787.28104754221 0.9953983523720418 0.9762529446583864 1.0590851488194422 0.8928079858005813 0.8891601977686403 0.9066443834638923 0.6700598375851766 0.8492099374885316 0.7861568971661607 1.0 14.475941173690211 -6.239177685045236 1.3300954234424776 0.8216680574332544 1.0062701156820253 0.398388789377655 0.08453642298890642 0.39524366206851935 1.4159004121683214 0.0319656476831773 0.046220320555193165 5.76530536348217e-07 6.239177685045236 0.18460205824877085 S(ph)PAPRPPR ddPTM_PC-9_AZD4547_30min_R2 4 SPAPRPPR 8 1 F8VP90;P50281 F8VP90 MMP14 Matrix metalloproteinase-14 1 S(1)PAPRPPR;S(1)PAPRPPR;S(1)PAPRPPR;S(1)PAPRPPR 92.051 0.0038996 14975100.0 36852.5 33240.700000000004 46319.5 56071.6 48564.6 53210.6 40779.2 49018.7 41615.4 48436.5 True False 48570.82842038117 43985.106217682696 45705.273165376355 43145.15891758426 41822.243576015906 49883.33277030993 44408.46980022186 41443.98625266692 43815.10508447707 46740.7528779232 1.0391537454956647 0.9410440249553177 0.9778463193510961 0.9230736832645837 0.8947704305330001 1.0672342591612607 0.9501017220712562 0.8866777640683217 0.9374069176616112 1.0 15.512393352106182 -7.522132079813045 24.999807661940352 0.9309033505062103 0.970143241926136 0.058548024980033864 0.05455672915735664 71.50798308444108 2394510.5371578736 0.025273399595791876 0.014814549532581127 3.005162218651776e-08 7.522132079813045 0.039239891419925677 S(ph)PAPRPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPAPRPPR 8 1 F8VP90;P50281 F8VP90 MMP14 Matrix metalloproteinase-14 1 S(1)PAPRPPR;S(1)PAPRPPR;S(1)PAPRPPR 80.688 0.0089383 10671000.0 28639.1 25130.699999999997 35550.2 27222.600000000002 39349.3 27253.399999999998 32197.6 28288.9 32132.8 23800.399999999998 True False 33487.13398199137 27625.50981298968 36397.8515928843 25697.40597886 31639.087136313545 25824.183727131276 29147.61023756261 27546.346349567146 32602.68141071481 28115.224116137255 1.191067652303394 0.9825818815768751 1.2945958190670468 0.9140032415430932 1.125336472710303 0.9185124621613457 1.0367198254284162 0.9797662019616059 1.1596095153302333 1.0 14.779063926693189 -5.777145369751715 24.999912121345908 1.0192574495281015 1.1387318831273958 0.2666517640971485 0.10287386013666543 330.73729143694646 526448.0508572068 0.02705352528385429 0.04028248366469371 1.6705313500660596e-06 5.777145369751715 0.11947443359929433 S(ph)PAPRPPR ddPTM_PC-9_Lapatinib_30min_R1 3 SPAPRPPR 8 1 F8VP90;P50281 F8VP90 MMP14 Matrix metalloproteinase-14 1 S(1)PAPRPPR;S(1)PAPRPPR;S(1)PAPRPPR 96.331 0.0050723 6675400.0 17460.9 20950.1 21442.9 19677.300000000003 21526.2 19728.3 17814.199999999997 17956.1 21156.8 17894.1 True False 17211.904364063117 20901.5913306203 19679.947533987674 21124.434283548533 20260.071238137534 18884.566597913483 18736.532110449967 18790.405957965835 18773.89839301923 20987.071342610507 0.8201194003242088 0.9959270157043467 0.9377176649717223 1.006545121932241 0.9653596210445557 0.8998190500058832 0.8927654461443975 0.895332447830168 0.8945458890637197 1.0 14.357213238209999 -6.766206019573171 24.83600411271863 0.9084678950618684 0.9509553497413601 0.04691411314269922 0.05628436607000984 246.38762386104437 1283762.4499553568 0.018854139904255055 0.017167795167440263 1.7131444373766655e-07 6.766206019573171 0.042487454679491665 S(ph)PAQQEPPQR ddPTM_PC-9_AZD4547_30min_R2 2 SPAQQEPPQR 10 0 A0A669KBI3;F5GXF9;P51825;P51825-3;P51825-2 A0A669KBI3 AFF1 AF4/FMR2 family member 1 1 S(1)PAQQEPPQR;S(1)PAQQEPPQR 87.641 0.010498 11574500.0 21124.1 20604.5 30593.0 37641.0 33139.0 30108.0 37623.0 40214.0 28535.0 31528.0 True False 27841.124391424564 27264.5016820417 30187.31683088889 28963.44899765281 28538.22187077815 28225.342000437708 40971.37411459148 33999.850325788866 30043.301844642912 30424.214316376325 0.9150975634706409 0.8961448075050583 0.9922135216698128 0.9519867529352357 0.9380101511912171 0.9277262415695304 1.346669915237153 1.1175259933495767 0.9874799569917445 1.0 14.892932386399599 S(ph)PAQQEPPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPAQQEPPQR 10 0 A0A669KBI3;F5GXF9;P51825;P51825-3;P51825-2 A0A669KBI3 AFF1 AF4/FMR2 family member 1 1 S(1)PAQQEPPQR 98.182 0.004857899999999999 4687400.0 16893.0 22459.0 18746.0 18550.0 19694.0 18631.0 18949.0 19245.0 14034.0 14021.0 True False 19752.651248041315 24688.58109363987 19192.9757346009 17510.703639911426 15835.102074561908 17653.957561998977 17154.013541120265 18739.839141763016 14239.220700280459 16562.89630982506 1.1925843692159144 1.4905956441322812 1.1587934486564215 1.0572247336671503 0.9560587579823568 1.0658738201196551 1.0356892430066447 1.131434912784342 0.8597059616821845 1.0 14.015667354709109 -5.5421436287236725 3.388758738314953 1.0217793346980009 1.3427172156662104 0.6436544231677723 0.0964214902234929 0.13148811161274623 3.156472675594655 0.025074833067331256 0.05092997809643909 2.8698313220320813e-06 5.5421436287236725 0.3209378809682095 S(ph)PAQQEPPQR ddPTM_PC-9_Lapatinib_30min_R1 2 SPAQQEPPQR 10 0 A0A669KBI3;F5GXF9;P51825;P51825-3;P51825-2 A0A669KBI3 AFF1 AF4/FMR2 family member 1 1 S(1)PAQQEPPQR;S(1)PAQQEPPQR 104.01 0.0026656999999999996 9485900.0 32801.0 38105.0 33997.0 33866.0 41981.0 35696.0 31412.0 33844.0 46289.0 28872.0 True False 32333.25172503331 38016.77021366422 31201.897892215085 36356.61861366418 39511.76011782159 34169.365291440205 33038.35965990359 35416.515793596365 41075.44537522062 33862.48673047822 0.9548398492521666 1.1226809925759795 0.9214296085388068 1.0736547171812132 1.1668298442553158 1.0090624933545054 0.9756625354441891 1.0458923491203447 1.2130073524178104 1.0 15.047400302635225 S(ph)PAQSDSTTQR ddPTM_PC-9_AZD4547_30min_R2 1 SPAQSDSTTQR 11 0 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 S(1)PAQSDSTTQR 133.04 7.8018e-05 19819000.0 5340.8 4555.0 5089.1 4754.1 4984.9 5984.4 4708.9 5624.0 5985.6 5252.3 True False 7039.0633044589085 6027.314672120163 5021.615208841134 3658.11569511281 4292.832680637375 5610.194521968228 5127.982977651958 4754.940026663263 6301.986596155408 5068.418575675697 1.3888085996371156 1.1891903918603706 0.9907656863505352 0.7217469592327678 0.8469767475874022 1.1068925027014573 1.0117520684384913 0.938150619501539 1.243383217479282 1.0 12.30731995912409 -5.015427492496217 2.562721021360362 0.9717328770835342 1.3919534149924042 0.4913701114245871 0.13215279787080692 0.28754445031888054 3.3252648329618824 0.03732911538058704 0.20978337678511658 9.651004264053823e-06 5.015427492496217 0.42022053790887004 S(ph)PAQSDSTTQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPAQSDSTTQR 11 0 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 S(1)PAQSDSTTQR;S(1)PAQSDSTTQR 106.54 0.0024209 38513000.0 1768.6799999999998 5766.0 5206.26 1987.57 4926.76 4135.2 2765.5 1494.8400000000001 2732.3999999999996 2870.2 True False 2068.0825909776668 6338.410373833535 5330.396983250999 1876.212896688883 3961.396745042585 3918.3428323964454 2503.5318195138602 1455.6020339139018 2772.3561808070635 3390.5445395093025 0.6099558837463231 1.8694372835906954 1.5721359566692028 0.5533662439250594 1.1683659361737508 1.1556677066874717 0.738386353678806 0.42931217005176525 0.8176728394219218 1.0 11.72730128113879 -6.537429370964304 0.8306611433350707 0.7197047190319595 1.319698292446463 0.17267894064967104 0.39794071904916606 0.9529050607077695 1.4539650068287036 0.24250803094113602 0.2939138876171877 2.901152972994907e-07 6.537429370964304 0.5999935734145035 S(ph)PAQSDSTTQR ddPTM_PC-9_Lapatinib_30min_R1 2 SPAQSDSTTQR 11 0 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 S(1)PAQSDSTTQR;S(1)PAQSDSTTQR 125.84 0.00044086 38767000.0 848.8 5632.83 5351.299999999999 3679.4500000000003 6334.8 5914.8 3072.8 5711.599999999999 4684.74 4102.68 True False 836.6959563491434 5619.7875282150435 4911.336770615365 3950.0490272853845 5962.199518695989 5661.837792072233 3231.8945486741272 5976.981787220923 4157.095248700793 4811.822771522529 0.17388336937530244 1.1679124097159677 1.0206811438862176 0.8209049283075596 1.23907296710545 1.1766513566501842 0.6716570210775884 1.242145039629072 0.8639335748821497 1.0 12.23236779098443 -4.755518956949519 24.999999999866997 1.0243746356125694 0.17388199163882498 0.6629993021748588 0.18151295808395254 113.64123408243674 479822.0523560929 0.04332630757762624 0.38130764899439024 1.755824250816529e-05 4.755518956949519 -0.8504926439737444 S(ph)PARTPPSEEDSAEAER ddPTM_PC-9_AZD4547_30min_R2 2 SPARTPPSEEDSAEAER 17 1 O43765;K7EMD6 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 S(0.997)PART(0.003)PPSEEDSAEAER;S(0.99)PART(0.01)PPSEEDSAEAER 94.454 0.00082417 16751900.0 10173.7 9782.4 14663.8 17324.4 19631.6 13627.0 9533.2 15170.6 13749.0 10950.3 True False 13408.724973894095 12944.369494741672 14469.348430843278 13330.527239311838 16906.091206082514 12774.90153580327 10381.636331744494 12826.332355707282 14475.744070860183 10566.933330011918 1.2689324854365267 1.2249882809402632 1.369304412070797 1.2615322556688073 1.599905164355139 1.2089507084823126 0.982464449005167 1.213817855676091 1.3699096624132723 1.0 13.367269126987754 -6.985776915046221 24.98103089703422 1.1502720158730024 1.3419334406628987 0.3230759802432651 0.13992428970088108 303.3288797391229 532756.4311524723 0.05001745272607181 0.04409359934244444 1.033292042745215e-07 6.985776915046221 0.19166142478989623 S(ph)PARTPPSEEDSAEAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPARTPPSEEDSAEAER 17 1 O43765;K7EMD6 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 S(0.817)PART(0.183)PPSEEDSAEAER 103.88 0.0003895 8471700.0 11436.0 4440.6 10313.0 12320.0 12457.0 14152.0 12180.0 12369.0 14495.0 14149.0 True False 13371.888928704238 4881.433421096984 10558.901032270296 11629.750341978912 10016.140273322722 13409.844206827833 11026.222224436373 12044.326856038806 14706.961953154138 16714.101696577636 0.8000363508283699 0.2920547876106618 0.6317360767544167 0.6958046895430945 0.5992628533170656 0.8023072044352596 0.6596957721451516 0.7206086856887434 0.8799133940991589 1.0 14.0287781985958 -8.097550516306756 0.2980420984789329 1.0471631529662135 0.5170046615901489 0.47133387490844814 0.13117432684833674 1.3554859201980274 0.43655319074594257 0.26837853348577206 0.22331656478874012 7.988210189241326e-09 8.097550516306756 -0.5301584913760646 S(ph)PASIDR ddPTM_PC-9_Lapatinib_30min_R1 1 SPASIDR 7 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 S(1)PASIDR 74.165 0.034581 17261000.0 24332.0 14616.0 19539.0 20090.0 19310.0 17953.0 14403.0 14300.0 25309.0 14634.0 True False 23985.021218057685 14582.157550004364 17932.57884272113 21567.485618275383 18174.223764920684 17185.192040487047 15148.716865579752 14964.430204716587 22458.433904414822 17163.467401420712 1.397446137024289 0.8496044073703499 1.044810959424012 1.2565925703619845 1.0588899864963361 1.001265748846561 0.8826140144808858 0.8718768681599792 1.3085021446514833 1.0 14.067053418255334 -6.571180853407227 5.007166463037995 0.9983902196697654 1.1153431824265099 0.09397219039983151 0.17347884776758385 0.5201548038375385 28.961269624114728 0.0574903695127056 0.0582176828584808 2.6842264195117995e-07 6.571180853407227 0.1169529627567445 S(ph)PAWNETGR ddPTM_PC-9_AZD4547_30min_R2 2 SPAWNETGR 9 0 Q9UPQ9-1;Q9UPQ9;H0Y720 Q9UPQ9-1 TNRC6B Trinucleotide repeat-containing gene 6B protein 1 S(1)PAWNETGR;S(1)PAWNETGR 94.538 0.0057152 20665000.0 9731.5 16752.1 8857.4 11513.2 9368.1 9519.9 7096.5 5472.1 6175.8 3982.5 True False 12825.914572225485 22166.888719829665 8739.945088677647 8859.009617166823 8067.501020176734 8924.619148065865 7728.074752257882 4626.512681348515 6502.2401798544115 3843.073887178659 3.337410351389694 5.768010028061987 2.2742068836709146 2.3051884708026122 2.0992313072854762 2.3222606200313662 2.0109097506661118 1.2038573332622047 1.69193733213075 1.0 11.908044998674438 -5.386277348832527 5.773782587316534 1.8879686918661451 4.532465920268619 0.7125704466024747 0.6863029504719391 0.10867765678005799 4.609053055984369 0.17388212481642842 0.3689067542380896 4.108872367853373e-06 5.386277348832527 2.6444972284024737 S(ph)PAWNETGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPAWNETGR 9 0 Q9UPQ9-1;Q9UPQ9;H0Y720 Q9UPQ9-1 TNRC6B Trinucleotide repeat-containing gene 6B protein 1 S(1)PAWNETGR 67.252 0.046252 6928000.0 4558.6 5730.9 4908.2 2009.7 4624.6 5802.1 2674.2 3209.5 4449.7 3987.9 True False 5330.280943545915 6299.82587780136 5025.230102452157 1897.1030245353097 3718.4428279688727 5497.8276619867 2420.8804164686176 3125.254025746342 4514.7684444946535 4710.874701800971 1.1314843380377204 1.3372942981041147 1.066729730793096 0.40270717109288556 0.7893317193402128 1.1670502847135538 0.513891913861159 0.6634126831162703 0.9583715828333652 1.0 12.201779244879694 -5.533545497269793 24.900228953540726 0.7725930034013305 1.2262950544549427 0.417070103137395 0.21887813575592077 173.7750298443355 405655.1346355065 0.059474348202202945 0.1031392194257818 2.92721419643826e-06 5.533545497269793 0.45370205105361217 S(ph)PCGLTEQYLHK ddPTM_PC-9_AZD4547_30min_R2 2 SPCGLTEQYLHK 12 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 S(1)PCGLTEQYLHK;S(1)PCGLTEQYLHK 186.29 3.4939e-05 12721800.0 35544.0 43550.0 62550.0 57747.0 50916.0 58626.0 49605.0 66008.0 50476.0 55917.0 True False 46846.25263887194 57626.68583333331 61720.546130556024 44434.32133225626 43847.19227413437 54960.10695222739 54019.74890238177 55807.980312942585 53144.05831120367 53959.362849810175 0.8681765344276436 1.0679645346022841 1.143833857014736 0.8234775020589884 0.8125965533762529 1.018546254988271 1.0011191024019255 1.0342594383161607 0.9848903972258566 1.0 15.719585692645746 S(ph)PCGLTEQYLHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPCGLTEQYLHK 12 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 S(0.999)PCGLT(0.001)EQYLHK;S(1)PCGLTEQYLHK 168.67 0.00055318 9269600.0 28396.2 39670.0 44820.0 42697.0 59181.0 54011.0 54700.0 57744.0 53341.0 49054.0 True False 33203.11580948506 43608.17543010344 45888.678780796545 40304.8255155417 47584.907884363194 51178.568079068566 49518.42000629471 56228.2811848253 54121.01121374234 57947.10188874968 0.5729901017868053 0.7525514479365167 0.7919063643406425 0.6955451472434517 0.8211783908661998 0.8831946104453031 0.8545452385412327 0.9703381075515342 0.9339727000954612 1.0 15.822448889007571 -3.520156647166925 0.19677432170329134 1.0386008951944863 2.1552156948407138e-08 0.8473442478314012 0.04855530145577161 9.493423385136092 0.22391272052051142 0.10455907657079959 2.599176064947178 0.0003018862640077125 3.520156647166925 -1.0386008736423293 S(ph)PCGLTEQYLHK ddPTM_PC-9_Lapatinib_30min_R1 2 SPCGLTEQYLHK 12 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 S(0.621)PCGLT(0.379)EQYLHK;S(0.952)PCGLT(0.048)EQYLHK 147.39 3.9073000000000004e-05 12085700.0 43415.0 43567.0 52965.0 44530.0 68641.0 77916.0 74455.0 66866.0 87182.0 65123.0 True False 42795.89413866407 43466.123288248484 48610.422150812454 47804.88474772536 64603.67133339827 74583.71431106725 78309.91558888704 69972.83846633417 77362.64509284019 76379.42377905706 0.5603065854811874 0.5690815816309774 0.6364334757411622 0.6258869520410453 0.8458255919850542 0.9764896175024275 1.0252750245329727 0.916121580973755 1.0128728558705455 1.0 16.22089641558434 -6.382434272000609 1.8966749710235933 0.9867538815450788 0.5843505634457001 0.9686301933864526 0.03303138957641388 0.05484078632037638 0.3901319554853473 0.012048725211656964 0.014463846755533038 4.145393174582743e-07 6.382434272000609 -0.4024033180993787 S(ph)PCGSPTGSPK ddPTM_PC-9_AZD4547_30min_R2 1 SPCGSPTGSPK 11 0 A0A2R8Y8D8;A0A2R8Y5E1;A0A2R8YFD4;Q13191-3;Q13191-2;Q13191 A0A2R8Y8D8 CBLB E3 ubiquitin-protein ligase CBL-B 1 S(0.98)PCGS(0.02)PTGSPK 108.98 0.004022400000000001 0.0 11019.0 11715.0 12601.0 15907.0 12681.0 10570.0 8909.2 9541.2 6657.6 8860.2 True False 14522.81279056184 15501.644650688844 12433.902506652865 12239.886910700121 10920.462039993281 9909.056229062931 9702.101540592672 8066.826774964361 7009.507144240223 8550.007094834991 1.698573185902382 1.813056349398037 1.454256396367684 1.4315645326299395 1.2772459623560157 1.158952983214357 1.1347477765782972 0.943487728780656 0.8198247166922966 1.0 13.061709901816062 -6.1042535440636225 0.5196347618121576 0.8938860836299285 1.8936079182553986 0.9276112150270968 0.08298763820789777 0.32622844887628377 0.16303116408438303 0.06510321597099909 0.17099464267269818 7.865864411243216e-07 6.1042535440636225 0.9997218346254702 S(ph)PCGSPTGSPK ddPTM_PC-9_Lapatinib_30min_R1 1 SPCGSPTGSPK 11 0 A0A2R8Y8D8;A0A2R8Y5E1;A0A2R8YFD4;Q13191-3;Q13191-2;Q13191 A0A2R8Y8D8 CBLB E3 ubiquitin-protein ligase CBL-B 1 S(0.792)PCGS(0.121)PT(0.086)GS(0.002)PK 88.338 0.027512 0.0 10127.0 5322.8 9840.5 7260.0 8877.1 11026.0 11910.0 10692.0 10545.0 12999.0 True False 9982.58712293565 5310.475383631858 9031.452075428493 7793.924618650032 8354.966431050101 10554.443682861374 12526.641523922443 11188.78935306502 9357.311056227212 15245.859829921264 0.6547736391583501 0.34832245887566204 0.5923871907639816 0.5112158123973964 0.548015430041721 0.6922826131555665 0.8216421811341771 0.7338903464864667 0.6137607954300297 1.0 13.896129896731019 -6.838865027595001 2.7604202568191156 0.7701215547406359 0.5191073616374217 0.5290291551502206 0.11607686227999026 0.22049630411288904 3.4136483924626355 0.042368897719346245 0.03757541225293067 1.4492221807278467e-07 6.838865027595001 -0.25101419310321427 S(ph)PCNLAIPSEVDVEK ddPTM_PC-9_AZD4547_30min_R2 1 SPCNLAIPSEVDVEK 15 0 R4GND2;F6S7C4;Q8NEM7-2;Q8NEM7;Q8NEM7-3 R4GND2 SUPT20H Transcription factor SPT20 homolog 1 S(0.998)PCNLAIPS(0.002)EVDVEK 67.214 0.030287 2730800.0 9147.8 6920.2 10898.0 10025.0 10426.0 9907.7 8179.4 10751.0 8612.2 6749.3 True False 12056.61011393971 9157.019318113276 10753.485399373301 7713.891134706027 8978.52986585995 9288.16995276128 8907.350754402603 9089.679983402693 9067.423309845237 6513.009061327035 1.8511581974496991 1.4059583261576978 1.6510779116254235 1.1843820670401939 1.3785532587652445 1.4260950453627654 1.36762449898814 1.395619121332937 1.3922018570012147 1.0 12.669108518510027 -1.5228787456343302 0.03889023304179002 1.1722807948811639e-11 3.6786566730536125 0.539473904703571 0.14791785478823902 693.114292871612 2.0620671106965816 54.41426463360017 170.66538896614367 0.029999999975547052 1.5228787456343302 3.67865667304189 S(ph)PCPQEK ddPTM_PC-9_Lapatinib_30min_R1 1 SPCPQEK 7 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(1)PCPQEK 94.40899999999999 0.013456999999999998 11475000.0 27769.0 69393.0 25717.0 48751.0 73855.0 29824.0 137670.0 108870.0 58660.0 55323.0 True False 27373.00896778908 69232.32477199312 23602.647530490784 52336.31116856856 69510.99410451675 28548.497043139625 144797.87897551656 113928.49764947515 52053.09308281535 64885.50683673623 0.4218663042374711 1.0669921242380718 0.3637583904504183 0.8065947808692665 1.0712869097165116 0.43998264689482736 2.231590474277321 1.7558389107777184 0.8022298910878577 1.0 15.98560864591271 -7.239518845177962 24.998613064484484 1.5104015214536213 0.7190943326013238 0.4150024687401046 0.43446641026836597 749.1649864907621 854363.8075684914 0.1635027623616162 0.1265422359663667 5.760778204881693e-08 7.239518845177962 -0.7913071888522974 S(ph)PDAPGR ddPTM_PC-9_AZD4547_30min_R2 1 SPDAPGR 7 0 E7EUN2 E7EUN2 AGAP1 1 S(1)PDAPGR 77.732 0.029363 2844700.0 14600.0 17508.0 18100.0 17257.0 13974.0 17464.0 18681.0 18302.0 20961.0 20538.0 True False 19242.496301134655 23167.118612399525 17859.9821736701 13278.665267992212 12033.951308797905 16371.973319238889 20343.572810107726 15473.84643812074 22068.955667270377 19818.970871280686 0.9709129917042569 1.1689365085031018 0.9011558818904507 0.6699977185613651 0.6071935514187614 0.8260758555815438 1.0264696861524345 0.7807593309773522 1.1135268228911979 1.0 14.27459442999276 -10.07947022025117 18.68482222427331 0.9999999979196624 0.8875198110622002 0.02948827094391082 0.1725670281751177 0.0 0.0 0.1812067674207536 0.043949096597205896 8.327790280232964e-11 10.07947022025117 -0.1124801868574622 S(ph)PDAPGR ddPTM_PC-9_Lapatinib_30min_R1 1 SPDAPGR 7 0 E7EUN2 E7EUN2 AGAP1 1 S(1)PDAPGR 78.516 0.028217000000000002 3900300.0 7210.6 13867.0 12614.0 9591.9 15457.0 7411.7 11437.0 13985.0 10444.0 9195.7 True False 7107.775521737907 13834.891813485934 11576.925611448101 10297.320323640395 14547.849649631224 7094.718868516565 12029.151898329217 14634.794154752544 9267.686739804365 10785.164492499962 0.6590326486611008 1.2827705894617336 1.073412057785371 0.954767109097055 1.3488760101663582 0.6578220363213055 1.1153424601631554 1.356937501039472 0.8592995263307429 1.0 13.396760559821969 -4.742608572443625 24.92918018354977 1.0767137046379693 0.6590312319474936 0.2584868688402411 0.2097749754737512 1731.293172760396 2291850.480494602 0.05013463491206113 1.7613334444080775 1.8088036577122892e-05 4.742608572443625 -0.41768247269047576 S(ph)PDASSAFSPASPATPNGTK ddPTM_PC-9_AZD4547_30min_R2 2 SPDASSAFSPASPATPNGTK 20 0 Q53GS7-2;Q53GS7 Q53GS7-2 GLE1 Nucleoporin GLE1 1 S(1)PDASSAFSPASPATPNGTK;S(0.908)PDAS(0.053)S(0.038)AFSPASPATPNGTK 158.58 1.2084000000000002e-05 22611000.0 49177.0 53054.0 59365.0 54422.0 51630.0 64782.0 67340.0 75186.0 61113.0 52968.0 True False 64814.26305485613 70202.66797248369 58577.781311598104 41875.84871151837 44462.06569867152 60731.171299068534 73333.12954513419 63567.731302401204 64343.30841533776 51113.60644220443 1.2680432387048135 1.3734634055193071 1.1460310744817748 0.8192700853317512 0.8698675126543068 1.1881605608819434 1.4347085766302556 1.2436557646206983 1.2588293586384385 1.0 15.641419767262535 -6.995459231444924 24.98306752575204 1.2627218749862503 1.0913409308687072 0.10753826022362734 0.18326530098741786 267.26413243061955 1470461.5396651574 0.07172628945132485 0.06301744321162124 1.0105103557824823e-07 6.995459231444924 -0.17138094411754312 S(ph)PDASSAFSPASPATPNGTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPDASSAFSPASPATPNGTK 20 0 Q53GS7-2;Q53GS7 Q53GS7-2 GLE1 Nucleoporin GLE1 1 S(0.971)PDAS(0.024)S(0.004)AFSPASPATPNGTK;S(0.533)PDAS(0.392)S(0.075)AFSPASPATPNGTK;S(0.796)PDAS(0.089)S(0.06)AFS(0.054)PAS(0.002)PATPNGTK 187.5 1.1443e-11 13705900.0 68959.3 81715.3 84982.5 72028.5 94897.3 83679.5 98990.3 66136.9 76424.8 77636.0 True False 80632.74748174143 89827.45494639617 87008.80509792583 67992.97666454772 76302.8552909681 79291.1997106592 89613.222156291 64400.876452837896 77542.36811848324 91710.79223376219 0.8792067489310978 0.9794643875437739 0.9487302745804285 0.7413846833995286 0.8319942880493203 0.8645787238273266 0.9771284270217111 0.7022169897811603 0.8455097402368419 1.0 16.484803895114432 -5.6792864484982895 24.999940201765362 0.8443383766651397 0.9401687969335649 0.15451276217993892 0.08863358619623263 46.392830806331744 14113.588412652165 0.023582575196758382 0.040846211501189715 2.092731693228327e-06 5.6792864484982895 0.09583042026842525 S(ph)PDASSAFSPASPATPNGTK ddPTM_PC-9_Lapatinib_30min_R1 2 SPDASSAFSPASPATPNGTK 20 0 Q53GS7-2;Q53GS7 Q53GS7-2 GLE1 Nucleoporin GLE1 1 S(0.998)PDAS(0.001)SAFSPASPATPNGTK;S(0.998)PDAS(0.001)SAFSPASPATPNGTK 329.6 3.546799999999999e-178 19573700.0 54013.0 61665.0 56337.0 49324.0 73540.0 69842.0 74159.0 86643.0 74668.0 67915.0 True False 53242.764715228914 61522.218481186304 51705.189327108856 52951.45150004055 69214.5217852028 66855.02046965397 77998.59015722612 90668.75008582213 66258.10355110219 79654.017258951 0.6684253543941104 0.7723680562297419 0.6491221799776653 0.664768122465163 0.8689394981823709 0.8393176235206297 0.9792172804499844 1.1382822010227407 0.8318237526639817 1.0 16.281459503803674 -6.738959523301063 1.3618206691344592 0.9966544216640139 0.692068331390567 0.7014944444498694 0.08393218247086918 0.22653756546045212 0.879367810891887 0.038492104332118804 0.03546645787827378 1.8240656992243063e-07 6.738959523301063 -0.30458609027344685 S(ph)PDEEDYDYESYEK ddPTM_PC-9_AZD4547_30min_R2 2 SPDEEDYDYESYEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(1)PDEEDYDYESYEK;S(1)PDEEDYDYESYEK 163.23 1.9926e-05 15776800.0 13590.900000000001 16573.2 14913.7 13431.4 11935.3 20358.0 19565.2 22257.0 19263.8 15253.8 True False 17912.523491718584 21930.162793409858 14715.934593561522 10334.998243061395 10278.289613274335 19085.011041746755 21306.464897185364 18817.69206497942 20282.045140172842 14719.769104895362 1.2169024774825719 1.4898442113549546 0.9997394992199596 0.7021168721745967 0.6982643233076311 1.2965564137415473 1.4474727657310509 1.2783958723048998 1.377877940587236 1.0 13.84546742092841 -6.947235316706715 24.99907342149423 1.3095493912224707 1.0253556609001684 0.21794049612838073 0.24187828701889694 158.11770711244978 74912.94289109693 0.0950206743584534 0.08380034788370629 1.129183915553157e-07 6.947235316706715 -0.28419373032230233 S(ph)PDEEDYDYESYEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPDEEDYDYESYEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.999)PDEEDYDYESYEK;S(1)PDEEDYDYESYEK 181.75 1.7185999999999998e-05 9734100.0 16406.8 30813.0 19353.0 13659.1 17174.4 13290.1 18131.1 10985.0 13576.2 11893.2 True False 19184.147190929052 33871.91100397725 19814.44891666122 12893.824910399686 13809.199607461976 12593.143760116076 16413.590950203485 10696.655389569592 13774.726241352959 14049.34301348061 1.3654835797319136 2.410924907412148 1.4103470103654585 0.9177528727163838 0.9829071433597848 0.8963510783410098 1.1682817434562125 0.7613633875481544 0.9804534082580124 1.0 13.778215047123428 -5.539696575439845 4.349030697294052 0.9611556417710583 1.9015114156077106 0.6824954186623295 0.2543420819986953 0.09537623338132849 4.339381798000246 0.0641488310215565 0.1234067775348104 2.8860471671337703e-06 5.539696575439845 0.9403557738366524 S(ph)PDEEDYDYESYEK ddPTM_PC-9_Lapatinib_30min_R1 2 SPDEEDYDYESYEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(1)PDEEDYDYESYEK;S(0.999)PDEEDY(0.001)DYESYEK 162.7 0.00022553 20337000.0 19568.5 39408.0 29919.0 26961.0 37863.0 28940.6 39775.0 41845.0 37429.0 34823.0 True False 19289.44960157661 39316.753197220314 27459.175310679853 28943.801879259463 35635.97278152211 27702.878001833666 41834.354879430306 43789.271462682904 33213.3518751568 40842.10915126916 0.47229317981922087 0.9626523706599163 0.6723251046849172 0.7086754940117984 0.8725301783395958 0.6782920514518239 1.0242946740210237 1.072159895085197 0.8132134349904088 1.0 15.317769750748171 -7.264701740115344 24.850778517074147 0.9834303353091424 0.7416585561059462 0.44190952764983693 0.13683013881460504 254.76233563887 1940617.450875996 0.05263296592725694 0.03715215297991957 5.4362354699297445e-08 7.264701740115344 -0.24177177920319615 S(ph)PDELPSAGGDGGK ddPTM_PC-9_AZD4547_30min_R2 2 SPDELPSAGGDGGK 14 0 B4E2I7;A0A2R8Y5N1;A0A140T8Z0;A0A0G2JH68;O60610-2;O60610-3;O60610 B4E2I7 DIAPH1 Protein diaphanous homolog 1 1 S(1)PDELPSAGGDGGK;S(1)PDELPSAGGDGGK 141.46 0.0001328 8966700.0 35686.0 46110.0 44276.0 50888.0 54956.0 52325.0 49024.0 62670.0 43407.0 44922.0 True False 47033.405685088495 61014.15576980475 43688.8713105755 39156.55781176264 47326.308009610504 49053.1094783082 53387.0410279279 52985.79151333339 45701.405402853154 43349.294453192655 1.084986648072758 1.4075005496499167 1.0078335036744257 0.9032801642029673 1.091743443730373 1.1315780359764416 1.231555016093139 1.222298821277148 1.0542594978610376 1.0 15.403720892093133 -6.941659099294435 6.168549286562726 1.1504162881730926 1.1009016198127624 0.0 0.13627054432961466 1.0454952268625672 80.50005631741612 0.05188813902158528 0.04549933867208896 1.1437757926183565e-07 6.941659099294435 -0.04951466836033025 S(ph)PDELPSAGGDGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPDELPSAGGDGGK 14 0 B4E2I7;A0A2R8Y5N1;A0A140T8Z0;A0A0G2JH68;O60610-2;O60610-3;O60610 B4E2I7 DIAPH1 Protein diaphanous homolog 1 1 S(1)PDELPSAGGDGGK 137.46 7.1491e-05 4201400.0 20456.0 23908.0 25091.0 24885.0 30551.0 25432.0 23419.0 18386.0 19583.0 17981.0 True False 23918.79677558358 26281.42823753246 25689.26459814739 23490.774128258538 24564.75086218854 24098.301149522733 21200.582781122783 17903.38698157727 19869.364327603824 21240.812962482323 1.1260772748120038 1.237308020364069 1.2094294433797037 1.1059263206992276 1.156488261799456 1.1345281930634008 0.9981059961579343 0.8428767304340021 0.9354333265256424 1.0 14.374551363888157 -7.332243260056302 2.628848155368274 0.9163106935404277 1.168302136972049 0.8175441685720051 0.051090374979057745 0.11135947581809795 1.5081487173098496 0.02466647525553492 0.01565423991132121 4.653253792141367e-08 7.332243260056302 0.2519914434316213 S(ph)PDELPSAGGDGGK ddPTM_PC-9_Lapatinib_30min_R1 4 SPDELPSAGGDGGK 14 0 B4E2I7;A0A2R8Y5N1;A0A140T8Z0;A0A0G2JH68;O60610-2;O60610-3;O60610 B4E2I7 DIAPH1 Protein diaphanous homolog 1 1 S(1)PDELPSAGGDGGK;S(1)PDELPSAGGDGGK;S(1)PDELPSAGGDGGK;S(1)PDELPSAGGDGGK 138.19 1.7963e-05 29140600.0 100995.0 134120.0 118937.0 102097.0 136129.0 121675.0 128630.0 119569.0 137950.0 107111.0 True False 99554.79277978529 133809.4533803081 109158.45897009673 109605.55396560805 128122.1598599112 116471.24388827849 135289.8320085763 125124.61224809484 122412.61832209985 125624.99363356366 0.7924760025873299 1.065149931633969 0.868923100513754 0.8724820658325141 1.0198779411176055 0.9271343266930958 1.0769340407148922 0.9960168643914252 0.9744288519461819 1.0 16.938763997615332 -6.267796058807134 24.879527859441144 0.9991630671787701 0.9093690233693317 0.30450377632933767 0.07294939571392237 654.8880795673804 2563176.235858454 0.021747105079446202 0.02524662610011664 5.397640318555284e-07 6.267796058807134 -0.08979404380943845 S(ph)PDEVTLTSIVPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPDEVTLTSIVPTR 14 0 A0A0C4DGG1;Q9UKS6;H0YDM6 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 1 S(1)PDEVTLTSIVPTR;S(1)PDEVTLTSIVPTR 111.12 0.00043019999999999994 6265600.0 5068.01 6490.2 4785.71 7370.88 3373.9 5326.1 5847.5 4368.1 4512.46 3976.2 True False 5925.923995239796 7134.504163762477 4899.819476306244 6957.913490315379 2712.8085147438014 5046.7899399368125 5293.58246776615 4253.442003384517 4578.446190764395 4697.053584418116 1.2616258019491842 1.518931823011408 1.0431687414767372 1.4813357704492411 0.5775553686981989 1.0744586684467266 1.1270006553314496 0.9055553501656392 0.9747485542751342 1.0 12.197540336749022 -6.2379260339527605 24.953045897228805 0.9542484647099128 1.3198062131904442 0.5105445331657927 0.1835026409474958 664.4076408216933 705088.6223809078 0.0526892986379604 0.06798145103721805 5.781945131306816e-07 6.2379260339527605 0.36555774848053146 S(ph)PDEVTLTSIVPTR ddPTM_PC-9_Lapatinib_30min_R1 2 SPDEVTLTSIVPTR 14 0 A0A0C4DGG1;Q9UKS6;H0YDM6 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 1 S(1)PDEVTLTSIVPTR;S(1)PDEVTLTSIVPTR 132.24 1.3858e-05 5638200.0 6498.0 7461.0 5304.2 5296.0 5583.049999999999 3989.4 5808.1 6602.5 6303.7 1887.17 True False 6405.337328412739 7443.724512902472 4868.109150804107 5685.4855069380965 5254.665975698622 3818.7826617456153 6108.814998748437 6909.276253611278 5593.710925096199 2213.3648200040384 2.8939365397526524 3.3630807021180047 2.1994156168051977 2.568706909748264 2.3740623001720227 1.725329067866294 2.7599675135061066 3.1216165501350432 2.527243080101903 1.0 11.112025549010378 -5.264352665373139 24.96741837179745 2.3706680429714666 3.128508639643296 0.25157898463361317 0.566903286932111 339.5865958010502 2910351.2352201487 0.1445042626585897 0.3234028625383639 5.440606732795971e-06 5.264352665373139 0.7578405966718296 S(ph)PDIFSEQR ddPTM_PC-9_Lapatinib_30min_R1 2 SPDIFSEQR 9 0 Q9C0C6 Q9C0C6 CIPC CLOCK-interacting pacemaker 1 S(1)PDIFSEQR;S(1)PDIFSEQR 84.507 0.013153999999999999 2511600.0 8190.4 9229.6 9474.3 9910.5 10224.5 9998.0 9199.1 8468.0 11066.2 7258.6 True False 8073.603394064589 9208.229428264938 8695.359625855608 10639.351230458844 9623.115012140417 9570.408846476328 9675.384386458007 8861.454193953845 9819.8080237479 8513.239338523455 0.9483585593007517 1.0816363856465971 1.0213925957077274 1.249741820638646 1.1303705475064747 1.1241794651736208 1.1365103225367694 1.0409027447231132 1.1534749151609143 1.0 13.055492475138152 -4.523525242043781 1.3308830479088753 1.1176008566553703 0.7874300727821594 0.32223939877911256 0.06880002583260422 2.70542331401086 2.742241436882107 0.01952852936708918 1.4256316688030637 2.9955374808773448e-05 4.523525242043781 -0.33017078387321097 S(ph)PDKPGGSPSASR ddPTM_PC-9_AZD4547_30min_R2 1 SPDKPGGSPSASR 13 1 Q9Y3T9 Q9Y3T9 NOC2L Nucleolar complex protein 2 homolog 1 S(0.777)PDKPGGS(0.212)PS(0.011)AS(0.001)R 94.781 0.017768 13466000.0 7921.7 9013.7 10204.0 6174.1 8981.0 6610.6 8030.1 10194.0 8321.2 9370.4 True False 10440.635818404007 11927.20225248946 10068.688292824845 4750.756633894113 7734.143173344355 6197.238136976667 8744.763343635039 8618.751534816021 8761.041643933511 9042.345148127786 1.1546380554347382 1.3190385964153317 1.1135040885836527 0.5253898801770197 0.8553249236394949 0.6853573973848811 0.9670901962247745 0.9531544520395276 0.968890426146527 1.0 13.142481271329034 -5.537151372454885 24.987834798762844 0.8448246598822112 1.2316966312677067 0.556168506824315 0.14397957862286956 154.53403873370115 270549.8615318932 0.03969421415889218 0.06878916989530069 2.9030106396760248e-06 5.537151372454885 0.38687197138549545 S(ph)PDKPGGSPSASR ddPTM_PC-9_Lapatinib_30min_R1 2 SPDKPGGSPSASR 13 1 Q9Y3T9 Q9Y3T9 NOC2L Nucleolar complex protein 2 homolog 1 S(1)PDKPGGSPSASR;S(0.991)PDKPGGS(0.007)PS(0.002)AS(0.001)R 113.43 0.0016671 29597000.0 12946.0 19098.6 15913.2 13349.3 15847.3 17766.7 17316.0 17826.9 15692.400000000001 12506.099999999999 True False 12761.387665994358 19054.37836511448 14604.878122728385 14331.052053959358 14915.192970990558 17006.85965720054 18212.537752161283 18655.202854298044 13924.956663702222 14667.762721669218 0.8700295953889067 1.2990650807955024 0.9957127341003457 0.9770441699869862 1.0168689836355072 1.1594719644650162 1.2416711462924908 1.2718506024601854 0.9493579169460097 1.0 13.840361212626041 -6.766020561698578 24.892313429516005 1.1487860557515888 1.0415546449992403 0.0874649004038589 0.13725907024796732 240.70846086678597 1307905.4270499633 0.046839925074128895 0.04268312424061384 1.713876162016716e-07 6.766020561698578 -0.10723141075234843 S(ph)PDLEASLDTLENNCHVGSDIDFRPK ddPTM_PC-9_AZD4547_30min_R2 1 SPDLEASLDTLENNCHVGSDIDFRPK 26 1 Q13111;Q13111-3;Q13111-2;K7EJF1 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 S(0.793)PDLEAS(0.198)LDT(0.008)LENNCHVGSDIDFRPK 70.315 0.00010994 3022300.0 8832.1 5675.0 10400.0 12653.0 10411.0 12514.0 8807.5 13681.0 10319.0 12081.0 True False 11640.524080907637 7509.332769326436 10262.08920476071 9736.046336901283 8965.612356941107 11731.497601749614 9591.350437611687 11566.91580810458 10864.44127334398 11658.047867170208 0.9984968507195858 0.6441329504636182 0.8802579404103663 0.8351352171334447 0.7690491975237838 1.0063003459426725 0.8227235423026122 0.9921829057399687 0.9319262879284385 1.0 13.509038609928675 -7.324108940297423 0.713424214978648 0.9850390309884991 0.8168073100518942 0.23060458956172447 0.10087940249564523 0.9579952738263906 0.9553664142884805 0.08214850219336825 0.05093855034708832 4.7412303927819564e-08 7.324108940297423 -0.16823172093660488 S(ph)PDNSIK ddPTM_PC-9_Lapatinib_30min_R1 1 SPDNSIK 7 0 Q9UKL0 Q9UKL0 RCOR1 REST corepressor 1 1 S(1)PDNSIK 73.985 0.034872 13417000.0 35998.0 114500.0 59316.0 70592.0 137950.0 77914.0 188950.0 181870.0 93965.0 99280.0 True False 35484.6619187753 114234.88228485886 54439.26744638143 75783.57116800862 129836.05222013502 74581.79984640499 198732.9064605497 190320.34414907714 83381.67220468364 116440.41571771564 0.30474523557868527 0.9810586949620343 0.4675289684499027 0.6508356286852268 1.1150428433276482 0.6405147163611324 1.7067347727642457 1.6344869861205857 0.7160887539840487 1.0 16.829232369755715 -6.704754827811541 1.3927661290851283 1.275827510138646 0.6241984344219107 0.34522149483713627 0.357600110489251 0.44725231278060723 1.812823219166495 0.16135109454957758 0.15325353487232105 1.9735365419383078e-07 6.704754827811541 -0.6516290757167353 S(ph)PDPFGAVAAQK ddPTM_PC-9_AZD4547_30min_R2 1 SPDPFGAVAAQK 12 0 Q9Y3Q8;Q9Y3Q8-2 Q9Y3Q8 TSC22D4 TSC22 domain family protein 4 1 S(1)PDPFGAVAAQK 155.86 0.00034048 6003500.0 37595.0 55344.0 42172.0 32343.0 41456.0 57174.0 59164.0 71772.0 46649.0 41599.0 True False 49549.427975421764 73232.86568909299 41612.77172530472 24886.821044368775 35700.54998264818 53598.90074176383 64429.48138414504 60681.28655648582 49114.770904179 40142.631671750176 1.2343343201958403 1.8243165093889349 1.0366229116609995 0.6199598782628527 0.8893425392379531 1.3352114325748932 1.605013889248482 1.511641963403945 1.2235065031559165 1.0 15.292847579591495 -6.975795670264239 23.752607174956204 1.3908825184859148 1.1259589069180531 0.08777485043486166 0.3256824795785808 305.7158501944364 300008.0879132493 0.12688456761673098 0.11189452884921569 1.0573148446798752e-07 6.975795670264239 -0.2649236115678617 S(ph)PDPFGAVAAQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPDPFGAVAAQK 12 0 Q9Y3Q8;Q9Y3Q8-2 Q9Y3Q8 TSC22D4 TSC22 domain family protein 4 1 S(1)PDPFGAVAAQK 67.749 0.036148 6600000.0 12143.0 21234.0 31062.0 32760.0 52498.0 42911.0 59664.0 42356.0 42521.0 50072.0 True False 14198.570064817715 23341.97118938283 31802.63588329098 30924.563409353 42211.39376004626 40660.6716195018 54012.19399004693 41244.1998798916 43142.78918317124 59149.65723026612 0.2400448409961789 0.39462563744898665 0.5376639083382208 0.5228189791356779 0.7136371660738421 0.6874202408513072 0.9131446659070339 0.6972855264288408 0.7293835873844359 1.0 15.852082187782678 -5.265578150569289 0.40053710640046164 0.8717106814364411 5.1644702781722e-23 0.8484097979714449 0.0841741243225857 1.519327237964976 0.2567364972401841 0.07435830917076033 0.6129739319348241 5.42527615603002e-06 5.265578150569289 -0.8717106814364411 down S(ph)PDPFGAVAAQK ddPTM_PC-9_Lapatinib_30min_R1 2 SPDPFGAVAAQK 12 0 Q9Y3Q8;Q9Y3Q8-2 Q9Y3Q8 TSC22D4 TSC22 domain family protein 4 1 S(1)PDPFGAVAAQK;S(1)PDPFGAVAAQK 98.105 0.0037625 14646200.0 34581.0 62016.0 53051.0 53825.0 86900.0 100800.0 133873.0 133447.0 114396.0 86091.0 True False 34087.86859862129 61872.405762251656 48689.35156278208 57783.4700549364 81788.71285197341 96489.01897627667 140804.2888943802 139647.43479222484 101511.51783671584 100971.71464095323 0.33759819489878756 0.6127696848792222 0.48220783152903013 0.5722738319380776 0.8100160836409194 0.9556044414951589 1.394492402105562 1.383035192467506 1.0053460832836414 1.0 16.623591679667577 -6.646248430143392 1.5626054153839875 1.2224956912799916 0.49554316255854775 0.815285304869081 0.14706758084728358 0.15075561716615496 0.761349585173049 0.06164573964344815 0.06146248020498845 2.2581436712828152e-07 6.646248430143392 -0.7269525287214438 down S(ph)PDQPPPCPQFMAQGK ddPTM_PC-9_Lapatinib_30min_R1 1 SPDQPPPCPQFMAQGK 16 0 P49023-3 P49023-3 PXN Paxillin 1 S(1)PDQPPPCPQFMAQGK 96.24700000000001 0.014163999999999998 0.0 4831.2 8139.0 5558.1 4215.1 6510.6 5846.3 8238.4 8770.8 5856.7 4984.3 True False 4762.3062020664265 8120.1546455586695 5101.1344728864515 4525.092515161398 6127.65930833209 5596.267377390936 8664.94404119921 9178.323387379593 5197.05677221488 5845.82961383772 0.8146501893920284 1.3890508588100776 0.8726108713143993 0.7740719134971036 1.048210384686418 0.9573093550561169 1.482243687138663 1.5700634458543736 0.8890195430795444 1.0 12.513192064737687 -7.238134916547827 24.56332513398236 1.282836965225526 0.9841660937377401 0.19910079440247208 0.24727018425516303 897.4427967773424 945921.8565591408 0.09392453622589465 0.07270643985329625 5.779164858116033e-08 7.238134916547827 -0.2986708714877859 S(ph)PDREASGSGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPDREASGSGGR 12 1 A0A494C050;Q8N5F7 A0A494C050 NKAP NF-kappa-B-activating protein 1 S(1)PDREASGSGGR 109.15 0.006503 14696000.0 5290.6 10841.0 10702.0 3973.9 17527.0 17318.0 6850.2 8293.5 15809.0 19187.0 True False 6186.194085886898 11917.222834326984 10957.176267561019 3751.2552665576295 14092.710168622256 16409.813593403374 6201.2994648468 8075.804412689613 16040.17671731037 22665.45121579158 0.27293496286439795 0.5257880251695126 0.48343075826025833 0.16550543074757043 0.6217705544200027 0.7240011874094194 0.2736014123789515 0.3563045948568189 0.7076928036682889 1.0 14.468207261722178 -14.522878743495177 0.21667607603185318 3.7462859660280032 0.3853131938771931 0.49481046118406435 0.173041214741809 136.00239179983285 1.3559555985242142 162.3002524375804 0.35330331476161064 3.0000000123314526e-15 14.522878743495177 -3.3609727721508103 S(ph)PDREASGSGGR ddPTM_PC-9_Lapatinib_30min_R1 1 SPDREASGSGGR 12 1 A0A494C050;Q8N5F7 A0A494C050 NKAP NF-kappa-B-activating protein 1 S(0.99)PDREAS(0.01)GSGGR 90.229 0.034081 16892000.0 5359.7 9663.5 4148.3 7027.3 10793.0 5216.6 12372.0 13853.0 7498.6 9157.7 True False 5283.269695151396 9641.124759473674 3807.2427869010758 7544.111084385589 10158.176959854425 4993.498178488539 13012.561623339083 14496.660952862865 6654.028704241377 10740.596243131768 0.49189724439458943 0.8976340364380454 0.35447220067840024 0.7023922055732968 0.94577402687027 0.46491815402536013 1.2115306570303448 1.349707281114209 0.6195213518519881 1.0 13.390786463481048 -7.266125068740489 24.928479120122006 1.0743321032284265 0.6577970927268704 0.3876570372572886 0.2462123735171787 395.7109470001119 2105222.2956508542 0.09812953360035594 0.06860832990109066 5.4184482668975066e-08 7.266125068740489 -0.41653501050155617 S(ph)PDSTANVR ddPTM_PC-9_AZD4547_30min_R2 2 SPDSTANVR 9 0 B7ZM87;O75044;E9PDX4;A0A087WW56;A0A286YEY3;A0A075B7B5;P0DMP2 B7ZM87 SRGAP2;SRGAP2B SLIT-ROBO Rho GTPase-activating protein 2;SLIT-ROBO Rho GTPase-activating protein 2B 1 S(0.772)PDS(0.114)T(0.114)ANVR;S(1)PDSTANVR 93.561 0.0061611999999999995 50448000.0 47251.0 42091.6 80652.0 87657.0 96855.0 67359.0 38403.1 64936.0 46317.0 22805.3 True False 62275.83511814482 55696.8865538997 79582.50178291944 67449.03293714975 83408.35508899514 63147.031081688794 41820.90150333749 54901.63328083321 48765.222061970446 22006.893388393095 2.8298330899803616 2.5308836449980454 3.616253342913587 3.0649047890023318 3.790101293124203 2.8694205023501356 1.9003546191301461 2.4947470918266683 2.215906679844701 1.0 14.425667880549549 -8.352374057463551 0.5969936019142976 1.03987627390311 3.1518997654341607 0.6695446156285256 0.44504818183706035 0.5122807723604202 0.4375847696155396 0.49057773903297724 0.22553475635430248 4.44248471815492e-09 8.352374057463551 2.1120234915310507 S(ph)PDSTANVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPDSTANVR 9 0 B7ZM87;O75044;E9PDX4;A0A087WW56;A0A286YEY3;A0A075B7B5;P0DMP2 B7ZM87 SRGAP2;SRGAP2B SLIT-ROBO Rho GTPase-activating protein 2;SLIT-ROBO Rho GTPase-activating protein 2B 1 S(0.995)PDS(0.002)T(0.002)ANVR 89.171 0.009551700000000002 17314000.0 5031.5 5335.5 11351.0 10373.0 15782.0 9275.4 15817.0 11917.0 15021.0 9833.2 True False 5883.233573345169 5865.173178908918 11621.650888907227 9791.834439719747 12689.630392034938 8788.981695591498 14318.699254836623 11604.191377105213 15240.653708059901 11615.881320431625 0.5064818941458124 0.5049270922381445 1.0004966965757005 0.8429695663725928 1.0924380201538952 0.7566349425533658 1.2326829846006524 0.9989936240734614 1.3120531527170929 1.0 13.503810998042288 -4.75693148060655 0.5671312248686894 1.1008295292127097 1.1336785841439756e-18 0.6359311884253336 0.15688004550886636 2.5047468150922136 0.6007843760053003 0.0821931315082192 1.8381926425901696 1.7501227867505163e-05 4.75693148060655 -1.1008295292127097 S(ph)PDSTANVR ddPTM_PC-9_Lapatinib_30min_R1 2 SPDSTANVR 9 0 B7ZM87;O75044;E9PDX4;A0A087WW56;A0A286YEY3;A0A075B7B5;P0DMP2 B7ZM87 SRGAP2;SRGAP2B SLIT-ROBO Rho GTPase-activating protein 2;SLIT-ROBO Rho GTPase-activating protein 2B 1 S(0.996)PDS(0.002)T(0.002)ANVR;S(0.999)PDSTANVR 109.16 0.0023875 38641000.0 23684.3 27736.9 36975.0 21184.4 27733.0 28909.0 25278.4 27066.7 38421.0 18627.7 True False 23346.557538831326 27672.676912200055 33935.05822762752 22742.37144508674 26101.79946517584 27672.62946017045 26587.19186383887 28324.317693846315 34093.62238893367 21847.473125149965 1.0686159175065273 1.2666305505300903 1.5532715400648691 1.0409611818634807 1.1947285306477142 1.266628378561308 1.2169458550898833 1.2964573766309138 1.560529320422251 1.0 14.415178807072738 -7.934978209404488 6.72687832152415 1.3281303372809268 1.2372428683172583 0.005110599803646254 0.18235298579352624 0.749197731992184 60.9175970986398 0.09893878949967246 0.046797310461888494 1.1615068906385638e-08 7.934978209404488 -0.0908874689636685 S(ph)PEALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPEALK 6 0 A0A3B3ITI3;A0A3B3IS53;A0A3F2YNX6;Q92794 A0A3B3ITI3 KAT6A Histone acetyltransferase KAT6A 1 S(1)PEALK 89.296 0.038149 3535600.0 27420.0 43247.0 31635.0 34242.0 59379.0 42859.0 30717.0 39545.0 35576.0 41663.0 True False 32061.66443031392 47540.27635053401 32389.2983764056 32323.53175406185 47744.11120571806 40611.398591042576 27807.26338817835 38506.98565139092 36096.23169682041 49216.17209587346 0.6514457151981987 0.96594827118869 0.6581027535687053 0.6567664728393622 0.9700898946938048 0.8251636984674728 0.5650025632633436 0.7824051325320269 0.7334221691704241 1.0 15.586844832691774 -10.949106582311986 2.7929616996347235 1.0059851436480738 0.7602505502635046 0.24636351259311773 0.1276212382822019 20893586.884709273 23307724.714571852 988822.7207041614 0.03227312024728364 1.1243290130779128e-11 10.949106582311986 -0.24573459338456916 S(ph)PEASQTDSPVESPR ddPTM_PC-9_AZD4547_30min_R2 1 SPEASQTDSPVESPR 15 0 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 S(0.999)PEAS(0.001)QTDSPVESPR 146.1 0.00011519 4679400.0 5709.4 1628.8 3565.0 9003.2 9231.5 6869.7 2146.8 3046.4 3326.9 3878.4 True False 7524.870437102625 2155.277747079984 3517.7257706703804 6927.651338053397 7949.865572289102 6440.136573017367 2337.8610410973333 2575.648879307783 3502.7531419990373 3742.618396493083 2.010589817052574 0.5758742994208352 0.9399103509902501 1.8510172836602208 2.1241453790047906 1.7207569382579637 0.6246592073848516 0.6881943619261914 0.9359097751673522 1.0 11.869832240847353 -7.2639564685942695 24.94713210732762 0.7862070130145745 1.507174074455933 0.3747077614525932 0.45725888599646974 272.65779398977025 2702315.5010311576 0.20471219040659772 0.14527097805497832 5.445572336737701e-08 7.2639564685942695 0.7209670614413585 S(ph)PEASQTDSPVESPR ddPTM_PC-9_Lapatinib_30min_R1 1 SPEASQTDSPVESPR 15 0 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 S(0.984)PEAS(0.016)QTDSPVESPR 184.92 4.5705e-07 7284400.0 11047.0 8390.6 7905.5 7018.9 7973.2 6803.8 7390.9 8464.7 11273.0 9585.3 True False 10889.467754228313 8371.172081216926 7255.540306112492 7535.093320364017 7504.232051914326 6512.817334432453 7773.564638048559 8858.000863906607 10003.316030047352 11242.106333390584 0.9686323391093636 0.744626659183378 0.645389759796396 0.6702563645020654 0.6675112144799535 0.5793235841479724 0.6914686987935718 0.7879307134462108 0.8898079891253247 1.0 13.456624745361236 -8.307474185545326 1.7872724931357165 0.9931783680768711 0.7011239016188561 0.4881801554318651 0.0975372154145084 0.2950988380552508 1.8152999633675346 0.09672397119900397 0.02840249764069352 4.9263562473027675e-09 8.307474185545326 -0.292054466458015 S(ph)PEAVGPELEAEEK ddPTM_PC-9_AZD4547_30min_R2 2 SPEAVGPELEAEEK 14 0 Q96N64-3;Q96N64-2;Q96N64 Q96N64-3 PWWP2A PWWP domain-containing protein 2A 1 S(1)PEAVGPELEAEEK;S(1)PEAVGPELEAEEK 210.02 3.7249e-11 43168000.0 19053.6 22955.0 22589.0 27123.0 27435.0 26099.0 25256.0 29098.0 21438.0 25218.0 True False 25112.248460499955 30374.754840508966 22289.455100609597 20870.211396172723 23626.12381257124 24467.025404192384 27503.735072644988 24601.572705520568 22571.168913455593 24335.125495761822 1.0319342082239713 1.2481856666734263 0.9159375448666375 0.857616756478509 0.9708650903273928 1.0054201449856313 1.1302072420968203 1.010949078927296 0.9275139722368213 1.0 14.570752594134897 -5.271314755595693 24.998931269366974 0.9796638495280868 1.1400599430811966 0.3773451228101744 0.08357927372545063 670.5801346292047 1697535.5538864427 0.023261828962551502 0.049391593954792375 5.354084787428728e-06 5.271314755595693 0.1603960935531098 S(ph)PEAVGPELEAEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SPEAVGPELEAEEK 14 0 Q96N64-3;Q96N64-2;Q96N64 Q96N64-3 PWWP2A PWWP domain-containing protein 2A 1 S(1)PEAVGPELEAEEK;S(1)PEAVGPELEAEEK;S(1)PEAVGPELEAEEK;S(1)PEAVGPELEAEEK;S(1)PEAVGPELEAEEK 196.97 9.1206e-19 38124000.0 34076.3 31840.4 25389.199999999997 37046.7 41875.9 33786.200000000004 31766.0 36596.799999999996 30742.7 31702.300000000003 True False 39844.744552396296 35001.30448612721 25994.57481707719 34971.09350602192 33670.61800366342 32014.39219479414 28756.89451407603 35636.172777514825 31192.25382802563 37449.67603473129 1.0639543187354623 0.9346223570443325 0.6941201518798055 0.9338156483273526 0.8990897003337726 0.8548643295366187 0.7678809954832863 0.9515749280304963 0.8329111792341689 1.0 15.192665617990267 -4.884872570905953 4.164894941481658 0.861947387912021 1.061718375192983 0.32953292246315147 0.08502061551496261 0.23278990816483383 6.658275397959437 0.020410935465099034 0.10698761683415922 1.3035492049712434e-05 4.884872570905953 0.1997709872809621 S(ph)PEAVGPELEAEEK ddPTM_PC-9_Lapatinib_30min_R1 2 SPEAVGPELEAEEK 14 0 Q96N64-3;Q96N64-2;Q96N64 Q96N64-3 PWWP2A PWWP domain-containing protein 2A 1 S(1)PEAVGPELEAEEK;S(1)PEAVGPELEAEEK 137.73 7.5743e-05 52502000.0 18439.8 16939.8 15941.8 12192.2 14084.4 13935.1 12633.1 11736.099999999999 12798.3 12576.3 True False 18176.84507055483 16900.576933878205 14631.126741127586 13088.855059986907 13255.9832829958 13339.128257304686 13287.18010376696 12281.402050739465 11356.820681926283 14750.096698133597 1.2323204005065838 1.1457943144207807 0.9919342930801894 0.8873741866141871 0.8987048393162836 0.9043417497725661 0.9008198641469416 0.8326319685953986 0.769948896902033 1.0 13.848436792021252 -5.246615292160041 1.3628830832699241 0.875004444822905 1.2659240814658728 0.8289845278819278 0.05534968527943599 0.2406415527128825 0.6809571836201785 0.017067770474401806 0.1025468898684975 5.667410987864501e-06 5.246615292160041 0.3909196366429678 S(ph)PEAVGSECPSR ddPTM_PC-9_AZD4547_30min_R2 2 SPEAVGSECPSR 12 0 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 S(1)PEAVGSECPSR;S(0.997)PEAVGS(0.003)ECPSR 150.14 0.00017087 29240000.0 18442.8 18736.0 23205.6 30631.6 28890.8 20475.8 20377.1 26641.0 21020.7 24483.8 True False 24307.226765929197 24792.0455975507 22897.878581730318 23569.95787350236 24879.811111508407 19195.444989124575 22190.62242432665 22524.24559927738 22131.811287390407 23626.62961428871 1.0288063580269986 1.0493263746157504 0.9691555230493957 0.997601361611388 1.0530410607724516 0.8124495665482357 0.9392208193294906 0.9533414611813849 0.9367316307360961 1.0 14.528126220221626 -6.717262667376491 24.999998493759517 0.9261112743068578 1.0172153196609324 0.45816509537867134 0.04954610168539948 124.6478978160038 70538.95995576357 0.016254864870786697 0.016254782421288326 1.9175086538360793e-07 6.717262667376491 0.09110404535407457 S(ph)PEAVGSECPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPEAVGSECPSR 12 0 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 S(1)PEAVGSECPSR;S(1)PEAVGSECPSR 181.98 0.00017087 29125000.0 13723.699999999999 17447.699999999997 16635.4 18595.8 14231.8 16226.2 18072.6 16389.0 11068.0 11606.1 True False 16046.851354569622 19179.792348167764 17032.051026105823 17553.937614397033 11443.18095383112 15375.269507407435 16360.632493706806 15958.806115580888 11229.848561401177 13710.194056162958 1.1704321097742814 1.398943900399873 1.2422910249362689 1.280356612203184 0.834647628396421 1.1214479856684447 1.1933188127525032 1.1640102284626046 0.8190874990827117 1.0 13.742961370935197 -6.209826427294448 23.456226671363748 1.0438156804603154 1.2798079630991603 0.47064299097226503 0.1290592159484767 169.78456093681294 77160.44257460105 0.03842740619102872 0.049609468106782524 6.168414831246532e-07 6.209826427294448 0.23599228263884497 S(ph)PEAVGSECPSR ddPTM_PC-9_Lapatinib_30min_R1 1 SPEAVGSECPSR 12 0 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 S(1)PEAVGSECPSR 124.48 0.00032101 16083000.0 2188.7 2430.0 4820.8 4714.6 5156.9 4618.2 1635.8 2326.1 7246.5 4791.8 True False 2157.4887366415783 2424.373484298756 4424.452432826144 5061.327411444555 4853.581280855486 4420.69035155001 1720.4937199691285 2434.179097845543 6430.322860972068 5620.056245327848 0.38389095099095766 0.43137886499164907 0.7872612371992448 0.9005830529991965 0.8636179192851388 0.7865918344189324 0.3061346087771694 0.43312361862377485 1.1441741114811481 1.0 12.456368853622436 -14.522878745280334 0.048033573272891844 2.28220018035297 8.645775217476156e-18 0.20357153985265586 0.2472699600219838 1294.5631407299295 4.591036680219271 220.31936608822704 51.99954039167714 3.000000000000026e-15 14.522878745280334 -2.28220018035297 S(ph)PEDQLGK ddPTM_PC-9_AZD4547_30min_R2 4 SPEDQLGK 8 0 Q9UK61-3;Q9UK61;Q9UK61-2 Q9UK61-3 FAM208A Protein FAM208A 1 S(1)PEDQLGK;S(1)PEDQLGK;S(1)PEDQLGK;S(1)PEDQLGK 114.4 0.0036791 26768900.0 82369.0 84631.0 85031.0 89019.0 84463.0 103384.0 100039.0 120887.0 103574.0 89026.0 True False 108560.62861836703 111986.315700593 83903.43338173168 68497.0448798399 72736.77038750531 96919.38213674944 108942.27719877749 102206.69185690657 109048.71018948812 85909.22683740559 1.2636666934953584 1.3035423530529695 0.9766521766111325 0.7973188375851582 0.8466700617055853 1.1281603350962757 1.2681091567145046 1.1897056418671543 1.269348057291646 1.0 16.39052546781307 -6.994061995703568 24.638916454922303 1.1976760029752798 1.0307947006069125 0.1448912973688724 0.16407375246587622 253.99397275231846 1053904.3187552423 0.0650523019145622 0.057204027133376203 1.0137666598282593e-07 6.994061995703568 -0.1668813023683673 S(ph)PEDQLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPEDQLGK 8 0 Q9UK61-3;Q9UK61;Q9UK61-2 Q9UK61-3 FAM208A Protein FAM208A 1 S(1)PEDQLGK;S(1)PEDQLGK 114.97 0.0036543 16934400.0 56728.0 73631.0 64545.0 60535.0 69758.0 47820.0 61577.0 47926.0 46403.0 42026.0 True False 66330.92997092819 80940.59906967351 66083.99758827551 57143.42020711795 56089.42066199295 45312.23501770118 55743.98078112636 46667.993281794465 47081.556089148806 49644.98112236708 1.3361054525820621 1.6303883542662179 1.3311314879018452 1.1510412314644334 1.129810494312433 0.9127253952622854 1.1228522908232397 0.9400344652516877 0.9483648704206407 1.0 15.599360254888987 -5.851233718127112 1.4199934767629419 0.9964808962777051 1.4949898420668548 0.8057490457830407 0.09482585584788658 0.16610728267687955 0.678945677840537 0.03113769528841094 0.06580913832001437 1.408530585411489e-06 5.851233718127112 0.4985089457891497 S(ph)PEDQLGK ddPTM_PC-9_Lapatinib_30min_R1 4 SPEDQLGK 8 0 Q9UK61-3;Q9UK61;Q9UK61-2 Q9UK61-3 FAM208A Protein FAM208A 1 S(1)PEDQLGK;S(1)PEDQLGK;S(1)PEDQLGK;S(1)PEDQLGK 130.98 0.0034321999999999994 30496100.0 138960.0 184521.0 181970.0 162008.0 197747.0 186668.0 189819.0 182673.0 176923.0 165407.0 True False 136978.40491785668 184093.7529614362 167009.12902451333 173922.60876284487 186115.91024556058 178684.64478436118 199646.8990284999 191160.65446057316 156996.06865821607 193997.37955902665 0.706083789529636 0.9489496888045484 0.8608834274160815 0.8965204022764971 0.9593733207562836 0.921067311272592 1.0291216277370092 0.9853775081658236 0.8092690170098283 1.0 17.56567763961865 -4.2647758292602065 1.8882213565411805 0.9365332929988266 6.490076468392554e-15 0.5242995729918607 0.06408890484577849 4.481975160974483 4.228250317654907 0.017281969411156253 12.102307510392482 5.435308145957822e-05 4.2647758292602065 -0.9365332929988202 S(ph)PEGTPQK ddPTM_PC-9_AZD4547_30min_R2 1 SPEGTPQK 8 0 C9J0I9;Q86WB0;Q86WB0-3;F8WAU5;F8WBD7;F8WDK5;F8WF13 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 S(1)PEGTPQK 107.21 0.0038138000000000004 35031000.0 131580.0 91900.0 88840.0 91544.0 95695.0 107410.0 94117.0 100830.0 121260.0 143470.0 True False 173419.7029659797 121604.87779755071 87661.92355297529 70439.94514070115 82409.40106593764 100693.63572030762 102493.23067121182 85249.04034289774 127669.5560428037 138447.15896886916 1.2526057180051948 0.8783486689307539 0.6331796492312761 0.5087857754924395 0.5952408245839699 0.7273073457791164 0.7403057703355123 0.6157514605414662 0.9221536721566899 1.0 17.07897592334875 -4.837075863982216 2.7264532715247998 0.6946245201781477 1.3228852343117417 0.5577014164097198 0.14289754638129581 0.26900322741903354 2.9710463208356677 0.03630536928286836 0.3659979048951051 1.4552048584286282e-05 4.837075863982216 0.628260714133594 S(ph)PEGTPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPEGTPQK 8 0 C9J0I9;Q86WB0;Q86WB0-3;F8WAU5;F8WBD7;F8WDK5;F8WF13 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 S(1)PEGTPQK 78.939 0.021419 34102000.0 71573.0 109350.0 101690.0 77750.0 143680.0 131030.0 90080.0 105850.0 115500.0 124650.0 True False 83688.89526881336 120205.5453310261 104114.67526147247 73393.91956890112 115526.93541551025 124158.5561348679 81546.97027727675 103071.54965734578 117188.9689954675 147248.05827114265 0.5683531331510571 0.8163472356944738 0.7070699368392054 0.4984372658670549 0.784573574496846 0.8431931639209956 0.5538067614251057 0.6999857985736543 0.7958608783803157 1.0 17.16788908410502 -8.618477564913945 2.406473716966871 0.999344035334222 0.6874650626054144 0.4416826635152574 0.1089490868454535 0.3969534054305756 5.12873163057431 0.10491973636213488 0.028510299951651975 2.4072568715860127e-09 8.618477564913945 -0.3118789727288076 S(ph)PEGTPQK ddPTM_PC-9_Lapatinib_30min_R1 2 SPEGTPQK 8 0 C9J0I9;Q86WB0;Q86WB0-3;F8WAU5;F8WBD7;F8WDK5;F8WF13 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 S(1)PEGTPQK;S(1)PEGTPQK 120.27 0.003423 87648000.0 141990.0 282110.0 196920.0 217104.0 264070.0 169427.0 293340.0 275250.0 249290.0 197408.0 True False 139965.1965622228 281456.7916277861 180729.99773318233 233070.55239771356 248537.92178159548 162181.0021636274 308527.70987635676 288039.11984952696 221212.33505992225 231529.7097703744 0.604523698928474 1.2156400658340054 0.7805909570414354 1.0066550535949246 1.073460170740461 0.7004759878309985 1.3325620724111265 1.244069800524508 0.9554382255275805 1.0 17.820837805668518 -7.2673478495882025 24.980202210293026 1.1533566609883574 0.9191083666542169 0.24960773415551685 0.19707971366785426 693.4550652505558 2931818.45273922 0.0771183118690211 0.05355044922553768 5.4032137740661006e-08 7.2673478495882025 -0.23424829433414052 S(ph)PEIHR ddPTM_PC-9_AZD4547_30min_R2 2 SPEIHR 6 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8;Q9NYF8-4;Q9Y2W1;A0A3B3ITZ9 E9PK91;Q9NYF8-2;Q9Y2W1 BCLAF1;THRAP3 Bcl-2-associated transcription factor 1;Thyroid hormone receptor-associated protein 3 1 S(1)PEIHR;S(1)PEIHR 96.19 0.034612000000000004 128296000.0 30962.0 44597.0 41523.0 37180.0 41847.0 50278.0 54731.0 50090.0 62453.0 42730.0 True False 40807.27195039259 59012.10810813234 40972.377889353775 28608.725425273813 36037.26638179948 47134.10871190406 59601.95297200399 42349.741453691866 65754.13807967355 41234.03570599976 0.9896502064786961 1.4311504342890642 0.993654324342356 0.693813373720077 0.8739689376695156 1.1430874496004233 1.4454552398646636 1.027057883823139 1.5946568642590078 1.0 15.33154804883024 -6.998665000986646 22.743728645579598 1.2726507541330783 1.0041192262526488 0.2237641717728741 0.237509358998836 22.877052058924637 389713.96944331465 0.08668476568801844 0.07570934759641354 1.0030786782527689e-07 6.998665000986646 -0.26853152788042944 S(ph)PEIHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPEIHR 6 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8;Q9NYF8-4;Q9Y2W1;A0A3B3ITZ9 E9PK91;Q9NYF8-2;Q9Y2W1 BCLAF1;THRAP3 Bcl-2-associated transcription factor 1;Thyroid hormone receptor-associated protein 3 1 S(1)PEIHR;S(1)PEIHR;S(1)PEIHR;S(1)PEIHR 108.09 0.031224000000000002 203549000.0 55061.4 112308.0 90129.6 66757.0 94694.0 72720.5 67550.4 40914.200000000004 60841.6 66872.7 True False 64382.20750777853 123457.1960222853 92278.63148241128 63016.82171911422 76139.39046656658 68906.90896287619 61151.537089455356 39840.245602178235 61731.29329900119 78996.19114599824 0.8150039460610118 1.5628246657375626 1.168140262761085 0.7977197483186061 0.9638362225065786 0.8722814095621982 0.7741074120451837 0.5043312218502632 0.7814464520816122 1.0 16.269495474013233 -5.730623741830166 5.010895746167785 0.7985044319447593 1.2283911572437232 0.3863893536174887 0.21084281072224081 0.17118820357654005 10.551134673972301 0.05809570738500339 0.09897102548697677 1.8594146919746715e-06 5.730623741830166 0.4298867252989639 S(ph)PEIHR ddPTM_PC-9_Lapatinib_30min_R1 3 SPEIHR 6 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8;Q9NYF8-4;Q9Y2W1;A0A3B3ITZ9 E9PK91;Q9NYF8-2;Q9Y2W1 BCLAF1;THRAP3 Bcl-2-associated transcription factor 1;Thyroid hormone receptor-associated protein 3 1 S(1)PEIHR;S(1)PEIHR;S(1)PEIHR 101.6 0.034816 131797000.0 28782.5 56262.0 53629.0 49352.0 61402.0 63764.0 73340.0 77591.0 57180.0 62975.0 True False 28372.056271935933 56131.72879572701 49219.83063392656 52981.51071344582 57790.455080976724 61036.96236114392 77137.1863446239 81196.1611198717 50739.786267906304 73860.14484108699 0.3841321504714014 0.7599731752015465 0.6663922842261543 0.7173220527449226 0.7824308387874835 0.8263856304704972 1.044368197633346 1.099323069221817 0.6869711178752079 1.0 16.172508471246957 -4.473177993895301 0.3630540637412729 0.9828347518860886 5.766754147266322e-15 0.5936633237919875 0.127842134227202 5.765529993319268 0.5111171887810613 0.11720013555112108 2.5955057283545235 3.363736796832603e-05 4.473177993895301 -0.9828347518860828 S(ph)PEIHRR ddPTM_PC-9_Lapatinib_30min_R1 1 SPEIHRR 7 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;Q9NYF8-2;Q9NYF8;Q9NYF8-4;Q9Y2W1;A0A3B3ITZ9 E9PK91;Q9NYF8-2;Q9Y2W1 BCLAF1;THRAP3 Bcl-2-associated transcription factor 1;Thyroid hormone receptor-associated protein 3 1 S(1)PEIHRR 65.465 0.026019 33099000.0 79293.0 91034.0 64403.0 38922.0 75349.0 15206.0 48398.0 79652.0 60261.0 65234.0 True False 78162.26727944467 90823.21636611209 59108.033942769274 41784.45371998577 70917.11996183376 14555.67482691729 50903.81162676728 83352.92270392216 53473.77160353798 76509.60998115873 1.0216006498882024 1.187082464392097 0.7725569893419301 0.5461334037681752 0.9269047375786886 0.1902463603003828 0.6653257236483477 1.0894438322773918 0.6989157521088715 1.0 16.223353348288256 -5.336587885615122 5.44423803243368 0.7144689662665377 1.1030640289491505 0.26752285890336513 0.24255632757307266 0.25853933335143625 13.654329045152341 0.06504445664120437 0.1404128165462667 4.606935314214407e-06 5.336587885615122 0.3885950626826128 S(ph)PENSTLEEILGQYQR ddPTM_PC-9_AZD4547_30min_R2 1 SPENSTLEEILGQYQR 16 0 Q86SQ7-2;Q86SQ7-3;Q86SQ7-4;Q86SQ7 Q86SQ7-2 SDCCAG8 Serologically defined colon cancer antigen 8 1 S(1)PENSTLEEILGQYQR 152.66 1.3387999999999998e-10 0.0 0.0 688.65 613.83 915.69 890.35 1275.0 462.03 818.12 521.26 947.32 True False 0.0 911.2426452152686 605.6902131306027 704.5918177694728 766.7402710596971 1195.2740484442038 503.1497749292904 691.6983525273383 548.8127394266188 914.154615141767 0.0 0.9968145761359561 0.662568676127804 0.7707578194091431 0.8387424384886917 1.3075184751529596 0.5503989878684384 0.75665356939654 0.600350017750016 1.0 9.836294385291572 -4.753987327853098 24.980279210436343 0.8230641856749326 7.726040786693039e-06 0.5783141615124217 0.21290619921736373 195.53454556954506 655402.9436996423 0.05293208429710254 0.5399974464040345 1.7620274593260982e-05 4.753987327853098 -0.8230564596341459 S(ph)PENSTLEEILGQYQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPENSTLEEILGQYQR 16 0 Q86SQ7-2;Q86SQ7-3;Q86SQ7-4;Q86SQ7 Q86SQ7-2 SDCCAG8 Serologically defined colon cancer antigen 8 1 S(0.956)PENS(0.034)T(0.01)LEEILGQYQR 108.96 0.0040897 0.0 0.0 0.0 619.0 641.91 833.66 0.0 530.96 0.0 533.98 734.65 True False 0.0 0.0 633.7593075705722 605.9458638002992 670.3103074783837 0.0 480.66362498249106 0.0 541.7884473090891 867.8362295138 0.0 0.0 0.7302752362915662 0.6982260514057781 0.772392629717615 0.0 0.5538644373625424 0.0 0.6242980286875356 1.0 9.761279005301194 S(ph)PEPAAPSGVR ddPTM_PC-9_Lapatinib_30min_R1 1 SPEPAAPSGVR 11 0 Q13505-2;Q13505 Q13505-2 MTX1 Metaxin-1 1 S(1)PEPAAPSGVR 67.749 0.038928 3445400.0 8129.2 5844.3 14379.0 5523.9 6900.0 7881.1 2485.7 6464.7 10103.0 5703.1 True False 8013.2761172873 5830.76788242272 13196.81412454513 5930.146033190214 6494.155565921943 7544.043724741412 2614.3973833764894 6765.073562547645 8965.093750693553 6688.873236096929 1.1980008940882818 0.871711523991307 1.9729502501748255 0.8865687573787174 0.9708893167351147 1.1278497077847882 0.39085766632079794 1.011392102041865 1.3402995443706207 1.0 12.707547489010954 S(ph)PEPDGPAPAFLR ddPTM_PC-9_AZD4547_30min_R2 1 SPEPDGPAPAFLR 13 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 S(1)PEPDGPAPAFLR 132.86 5.0945e-05 5823400.0 1840.3 2112.3 3316.8 1760.4 1764.2 1480.9 1919.8 3414.8 3942.5 3737.3 True False 2425.4771193820643 2795.059666722155 3272.8170648413807 1354.5669779088767 1519.271282308664 1388.2990888949187 2090.6584808546004 2887.121124297603 4150.892501226728 3606.458264545588 0.6725371379523432 0.7750151150229188 0.9074878522831745 0.3755948020320572 0.42126406875253036 0.3849480534803426 0.5796985095897186 0.8005419479494181 1.1509609142114219 1.0 11.816367013096519 -8.018237215855047 3.168108692103764 1.069596292902373 0.5861702711864448 0.5801241915338939 0.1650891257172268 0.2065567270181956 4.100845968954745 0.13906650447289748 0.050385632003236404 9.588767406829717e-09 8.018237215855047 -0.4834260217159282 S(ph)PEPDGPAPAFLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPEPDGPAPAFLR 13 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 S(1)PEPDGPAPAFLR;S(1)PEPDGPAPAFLR;S(1)PEPDGPAPAFLR;S(1)PEPDGPAPAFLR 196.7 9.498600000000001e-07 14015730.0 7641.76 13310.490000000002 14920.25 7373.0199999999995 12126.48 7376.14 12244.81 5553.3 7718.49 3897.52 True False 8935.35903636016 14631.867481236135 15276.005345363219 6959.933593053356 9750.383294665053 6989.322233447645 11084.892952052614 5407.531759207722 7831.358314301533 4604.109523248658 1.940735551845729 3.1780016108113553 3.3179065937129306 1.5116785467219793 2.117756592329104 1.518061679061879 2.4076084411282896 1.1745011129518417 1.7009496135477964 1.0 12.168706437586687 -6.654793843457966 0.35766427039270215 1.0814831087767802 3.0373418669772847 0.4305510533374186 0.5620730777380792 1.791959577630037 0.45369246138557123 0.6470279437736097 1.3360984503605633 2.214145499511056e-07 6.654793843457966 1.9558587582005045 S(ph)PEPDGPAPAFLR ddPTM_PC-9_Lapatinib_30min_R1 2 SPEPDGPAPAFLR 13 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 S(1)PEPDGPAPAFLR;S(1)PEPDGPAPAFLR 97.95700000000001 0.0028802 9934300.0 4160.7 8549.7 4554.0 7317.1 7965.0 8520.5 8614.0 8023.3 8803.7 8135.0 True False 4101.367655021066 8529.903694942002 4179.587698948361 7855.223943130056 7496.514359792506 8156.098077255611 9059.990771374296 8396.091808496682 7812.134598929114 9541.123910793858 0.4298621098905544 0.8940145599924697 0.4380603100877875 0.8233017427059567 0.7857055866669661 0.8548361968162504 0.9495726977326794 0.8799898090620326 0.8187855720112028 1.0 13.219943505297882 -6.191945584686409 1.3384415198706319 0.8978760932123916 0.61588359572605 0.46546638100412463 0.13641462888894837 0.40457182553441756 1.465609215839883 0.04907932649984969 0.07407486772608073 6.427682484914992e-07 6.191945584686409 -0.2819924974863416 S(ph)PEPDPYLSYR ddPTM_PC-9_AZD4547_30min_R2 1 SPEPDPYLSYR 11 0 H3BUL5;H3BVF8;H3BQG1;P49761-3;P49761-1;P49761;H3BRT8;H3BQR7;H3BV35;H3BRK0;P49761-2 H3BUL5 CLK3 Dual specificity protein kinase CLK3 1 S(1)PEPDPYLSYR 71.153 0.030438 2048400.0 4865.7 6846.7 9356.0 10571.0 7349.7 9333.9 7278.4 9138.9 8738.1 6717.2 True False 6412.891387152802 9059.76188048411 9231.9333268982 8134.019270321938 6329.321020056671 8750.249757469292 7926.163499870886 7726.692996030034 9199.97812681529 6482.032872556558 0.9893333639672695 1.3976729304846733 1.4242342654546063 1.2548562203008122 0.9764407469844169 1.3499236936171435 1.222789772237726 1.1920169409728054 1.4193044539724395 1.0 12.662230621725442 -6.00540133541742 24.85630960539871 1.2035206490744315 1.292540422195965 0.03733083285231775 0.16787397227061113 755.5513741239863 3476994.1836904404 0.04718289391505212 0.06768000325033365 9.876399858661517e-07 6.00540133541742 0.08901977312153364 S(ph)PEPDPYLSYR ddPTM_PC-9_Lapatinib_30min_R1 2 SPEPDPYLSYR 11 0 H3BUL5;H3BVF8;H3BQG1;P49761-3;P49761-1;P49761;H3BRT8;H3BQR7;H3BV35;H3BRK0;P49761-2 H3BUL5 CLK3 Dual specificity protein kinase CLK3 1 S(1)PEPDPYLSYR;S(1)PEPDPYLSYR 105.2 0.0025875 3436000.0 13717.4 15734.0 14474.400000000001 13781.7 15232.400000000001 16469.3 15569.9 18117.2 16320.599999999999 11971.0 True False 13521.787360536933 15697.568889694077 13284.370704799769 14795.252192403479 14336.46018005065 15764.946430813427 16376.03323789421 18958.9912520903 14482.402164462956 14040.171399645154 0.9630785106283444 1.1180468131671677 0.9461686988476161 1.0537800267009139 1.021102931863993 1.1228457247474817 1.166369894765536 1.3503390174118148 1.0314975332016942 1.0 13.777272927436133 -6.874510634991952 3.091647346683016 1.164753063890403 1.02258387085404 0.2282768366443283 0.09948343964027827 0.3135539081271774 5.988005611042587 0.03612448164454223 0.03156884092305353 1.3350248971072062e-07 6.874510634991952 -0.14216919303636288 S(ph)PEPDTLPLAAGSDHPLPR ddPTM_PC-9_AZD4547_30min_R2 2 SPEPDTLPLAAGSDHPLPR 19 0 H3BVB1;H3BME1;H7C112;H3BPZ0;Q6PCT2-2;Q6PCT2-3;Q6PCT2 H3BVB1 FBXL19 F-box/LRR-repeat protein 19 1 S(0.972)PEPDT(0.028)LPLAAGSDHPLPR;S(0.986)PEPDT(0.014)LPLAAGSDHPLPR 120.25 2.5695e-05 5484900.0 5866.0 13510.8 20702.5 24107.7 20823.9 27103.5 19573.7 36678.0 23170.4 20584.0 True False 7731.26597962027 17877.901881905833 20427.971323226793 18550.042225252124 17932.860931678602 25408.713860398017 21315.72138071868 31010.25787659232 24395.140040690898 19863.36042528199 0.3892224585413026 0.9000441767723716 1.028424742131053 0.9338823757958759 0.902811032359547 1.2791749893466127 1.073117585561612 1.5611788344293756 1.2281476808748273 1.0 14.277822093995566 -4.678069621280791 0.505077133572236 1.2513182417438196 4.0098371828225774e-13 0.6031675380108595 0.18248467960047832 3.553427160625195 0.6454164104468982 0.11612469984024798 2.7077492450309433 2.0986034317995347e-05 4.678069621280791 -1.2513182417434185 S(ph)PEPDTLPLAAGSDHPLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPEPDTLPLAAGSDHPLPR 19 0 H3BVB1;H3BME1;H7C112;H3BPZ0;Q6PCT2-2;Q6PCT2-3;Q6PCT2 H3BVB1 FBXL19 F-box/LRR-repeat protein 19 1 S(0.996)PEPDT(0.004)LPLAAGSDHPLPR;S(0.975)PEPDT(0.025)LPLAAGSDHPLPR 135.27 2.2974e-05 4977600.0 11453.900000000001 22854.9 34781.3 26558.3 36710.0 26144.9 26196.3 16929.4 23509.4 19942.1 True False 13392.819045163113 25123.783429227908 35610.61810081479 25070.324554170325 29516.939024939988 24773.81541853399 23714.796819212035 16485.021188182007 23853.180499584807 23557.444868423263 0.5685174737738659 1.0664901719839823 1.5116502787001223 1.0642208734519825 1.2529771029839027 1.0516342310002036 1.0066794999061928 0.6997796781551112 1.0125538076312322 1.0 14.52389544691981 -7.392828658450323 3.1583038274889783 0.8884288766643904 1.1120707287985752 0.0965170013249218 0.234376662515199 0.528711585389515 9.9558843264152 0.11323543447314936 0.07096715139857243 4.047355399071733e-08 7.392828658450323 0.22364185213418475 S(ph)PEPDTLPLAAGSDHPLPR ddPTM_PC-9_Lapatinib_30min_R1 3 SPEPDTLPLAAGSDHPLPR 19 0 H3BVB1;H3BME1;H7C112;H3BPZ0;Q6PCT2-2;Q6PCT2-3;Q6PCT2 H3BVB1 FBXL19 F-box/LRR-repeat protein 19 1 S(0.844)PEPDT(0.156)LPLAAGSDHPLPR;S(0.96)PEPDT(0.04)LPLAAGSDHPLPR;S(0.732)PEPDT(0.268)LPLAAGSDHPLPR 114.52 4.4825e-05 5061000.0 16607.8 19502.0 27076.1 19603.5 25778.7 25615.7 24247.2 19662.7 27202.300000000003 17234.9 True False 16370.969726502479 19456.84431719931 24850.007574768486 21045.206785358947 24262.44754887421 24520.176224113195 25502.601373539237 20576.30082421545 24138.49052108197 20213.929500939295 0.8098855655819793 0.9625463627096945 1.2293506600789204 1.0411239825676162 1.2002835741436018 1.2130336272803266 1.2616350211548026 1.0179268124616403 1.1941513162970272 1.0 14.303062182239934 -5.017352912225477 3.3419809096210895 1.1498690031033971 0.8199672751149498 0.5921433428994436 0.08971121635018958 0.15580506750835063 3.4821053359050707 0.02252079810521643 0.09796358795026062 9.608311796245778e-06 5.017352912225477 -0.3299017279884473 S(ph)PEPEATLTFPFLDK ddPTM_PC-9_AZD4547_30min_R2 1 SPEPEATLTFPFLDK 15 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 S(1)PEPEATLTFPFLDK 165.34 0.00028326 2300000.0 6931.5 7384.7 10965.0 10522.0 12559.0 12643.0 10358.0 13979.0 12543.0 11498.0 True False 9135.572815843492 9771.659859320698 10819.596935596279 8096.315463279486 10815.399634120004 11852.43121135691 11279.841933895183 11818.86675546334 13205.997372957981 11095.458519718826 0.8233614500570455 0.8806900446659797 0.9751374327043549 0.72969633917253 0.9747591426617384 1.0682236511715846 1.0166179174883734 1.0651985886350595 1.1902164610401913 1.0 13.43768166767527 -6.527526553370833 4.711154096898063 1.0662766126813235 0.8610275166169868 0.6528956040807053 0.0739375277317922 0.12379470773863042 7.375942321320781 0.02428492008501913 0.025518830629115943 2.9680652662620666e-07 6.527526553370833 -0.2052490960643366 S(ph)PEPEATLTFPFLDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 SPEPEATLTFPFLDK 15 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 S(1)PEPEATLTFPFLDK;S(1)PEPEATLTFPFLDK;S(0.999)PEPEAT(0.001)LTFPFLDK;S(0.962)PEPEAT(0.019)LT(0.019)FPFLDK;S(0.844)PEPEAT(0.145)LT(0.012)FPFLDK;S(0.814)PEPEAT(0.142)LT(0.044)FPFLDK;S(1)PEPEATLTFPFLDK 209.6 4.0549e-21 41168900.0 174049.3 239541.90000000002 236423.0 195395.1 289452.2 185489.6 235936.9 173910.0 190877.3 160069.1 True False 203512.4088596289 263322.03675473365 242060.22095921997 184447.74602646125 232736.11926000356 175762.1988402213 213587.2487967668 169345.04677287632 193668.5194081263 189088.36072370198 1.0762820518445526 1.3925872314240577 1.2801434209529219 0.9754579569071327 1.2308326031768828 0.929524155625036 1.129563173424846 0.895586836359141 1.0242223194854225 1.0 17.528701035804893 -6.171970905562331 0.947269422253655 0.9952569842584833 1.2607362242620763 0.3679713701279117 0.1227189476354488 0.5882594113782543 1.1071767432097903 0.05519093756711593 0.09785819004240531 6.730217421282814e-07 6.171970905562331 0.265479240003593 S(ph)PEPEATLTFPFLDK ddPTM_PC-9_Lapatinib_30min_R1 1 SPEPEATLTFPFLDK 15 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 S(0.956)PEPEAT(0.042)LT(0.002)FPFLDK 94.402 0.0030396 1919400.0 10198.0 16151.0 11979.0 13223.0 16205.0 19516.0 18191.0 19161.0 16576.0 13699.0 True False 10052.57464991584 16113.60335181449 10994.13286027722 14195.463530634914 15251.853760255814 18681.346174018003 19132.840970753412 20051.290010669552 14709.036326981728 16066.853897229883 0.6256716289459148 1.0029096831827584 0.6842741541436895 0.8835247784933415 0.9492744415187229 1.1627258387679051 1.1908268471932855 1.247991059041536 0.9154895178027194 1.0 13.9717998374224 -6.440690873184816 2.161758118193167 1.1236807418039394 0.7983226087397005 0.5419106646828142 0.1312601781260355 0.23230401448751653 2.1493814249223613 0.044772729262455756 0.05098705334232798 3.6250093143534795e-07 6.440690873184816 -0.3253581330642389 S(ph)PEPEVLSTQEDLFDQSNK ddPTM_PC-9_AZD4547_30min_R2 3 SPEPEVLSTQEDLFDQSNK 19 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 S(1)PEPEVLSTQEDLFDQSNK;S(1)PEPEVLSTQEDLFDQSNK;S(0.999)PEPEVLSTQEDLFDQSNK 193.36 6.7391e-15 11353400.0 55086.0 68108.0 65142.0 50507.0 60770.0 71356.0 68670.0 78300.0 78906.0 57510.0 True False 72602.20214002085 90122.57907546882 64278.17451697335 38863.39147537131 52333.134466555675 66894.09803983095 74781.4969685828 66200.53415500239 83076.81007020839 55496.59240468164 1.3082281090450554 1.6239299598486008 1.158236420143715 0.7002842839787192 0.9429972580107621 1.2053730714138013 1.3474970935742407 1.1928756575226729 1.4969713719431916 1.0 15.760111569538434 -5.344574501995957 7.372157139974206 1.1245215757886928 1.464634784900906 0.2737139166175847 0.21875976378846265 0.34640339471507253 26.763613887376955 0.06236013955321553 0.1308841156486701 4.5229886507968054e-06 5.344574501995957 0.3401132091122132 S(ph)PEPEVLSTQEDLFDQSNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPEPEVLSTQEDLFDQSNK 19 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 S(1)PEPEVLSTQEDLFDQSNK;S(1)PEPEVLSTQEDLFDQSNK;S(1)PEPEVLSTQEDLFDQSNK;S(1)PEPEVLSTQEDLFDQSNK 293.67 2.3366e-121 16476900.0 140837.0 230468.0 165896.0 148110.0 165671.0 112167.0 155764.0 84759.0 110344.0 129468.0 True False 164677.9224424549 253347.33993005005 169851.58980408317 139811.87687909868 133208.9568292246 106284.76506128168 141008.90628629757 82534.16605958376 111957.5722496611 152939.5235318761 1.0767518993096135 1.6565197411331458 1.1105800899705445 0.9141644595875748 0.8709910541957507 0.6949463592328343 0.9219912749166378 0.5396523027769323 0.7320381917256763 1.0 17.222601759062456 -5.7034371427819766 2.177861798698495 0.7777895708360256 1.3722404369086063 0.6049345470392143 0.18138070561802633 0.18361200844699774 1.7693444578512445 0.051733588062367844 0.10453897304073956 1.979533506492024e-06 5.7034371427819766 0.5944508660725807 S(ph)PEPEVLSTQEDLFDQSNK ddPTM_PC-9_Lapatinib_30min_R1 2 SPEPEVLSTQEDLFDQSNK 19 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 S(1)PEPEVLSTQEDLFDQSNK;S(1)PEPEVLSTQEDLFDQSNK 239.19 4.1642999999999997e-44 5598900.0 41290.0 74684.0 58008.0 55787.0 73485.0 66019.0 67625.0 75279.0 62404.0 58416.0 True False 40701.197028341376 74511.07378657129 53238.806157355386 59889.76207997652 69162.75677706876 63195.52126780569 71126.29160833376 78776.73715950061 55375.404376747545 68513.12776557279 0.5940642086521899 1.087544478213304 0.7770599284201325 0.8741355712863917 1.0094818180498015 0.9223855825709486 1.0381410676754137 1.1498050042182602 0.8082451667689469 1.0 16.06409282817288 -6.182695243058043 4.355931493772785 0.9948965169618152 0.8437119553969095 0.22963514383513572 0.13881602085734168 0.3616253943534203 12.789377997722017 0.04000277514747977 0.05204434386602482 6.566058639161034e-07 6.182695243058043 -0.15118456156490578 S(ph)PEPGQTWTR ddPTM_PC-9_AZD4547_30min_R2 4 SPEPGQTWTR 10 0 Q09666;E9PJZ0;E9PKR9;E9PJC6;E9PLK4;Q09666-2 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(1)PEPGQTWTR;S(1)PEPGQTWTR;S(1)PEPGQTWTR;S(1)PEPGQTWTR 128.36 0.00028212 507462000.0 66001.8 187912.0 161733.3 58739.6 80393.5 189459.2 180262.0 193579.9 95450.5 132426.0 True False 86988.9994772762 248650.87918055864 159588.61076733912 45198.09273777337 69232.2502178219 177612.28627372536 196304.9687862337 163666.57447856868 100495.81856394214 127789.80604733754 0.6807193951374543 1.9457802376540911 1.2488367867795516 0.35369090959438904 0.5417666115885331 1.3898783617210588 1.536155150853863 1.2807482814234903 0.786414986236971 1.0 16.963413229723862 S(ph)PEPGQTWTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SPEPGQTWTR 10 0 Q09666;E9PJZ0;E9PKR9;E9PJC6;E9PLK4;Q09666-2 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(1)PEPGQTWTR;S(1)PEPGQTWTR;S(1)PEPGQTWTR;S(1)PEPGQTWTR;S(1)PEPGQTWTR 145.14 0.00013651 483038000.0 117625.5 210755.2 202075.0 99423.8 221498.0 87686.9 181987.0 113347.8 71507.9 76495.0 True False 137537.17394047722 231677.58342340688 206893.23437370468 93853.40682230855 178097.05693669754 83088.44460003474 164747.87388821846 110372.54035192145 72553.5677578441 90362.93796591327 1.522052923869729 2.5638562516725645 2.2895806514364216 1.03862721747396 1.9709082168607595 0.9194969361374392 1.823179697304272 1.2214359430583832 0.8029128909599285 1.0 16.463443557318385 -6.4053056559538355 0.47496986950774756 0.9880603844574979 2.2581898796629276 0.3913241408783569 0.4577835824015942 1.355831597172309 0.6054471259416784 0.4030852187935134 0.7989282962507357 3.932731928143242e-07 6.4053056559538355 1.2701294952054298 S(ph)PEPGQTWTR ddPTM_PC-9_Lapatinib_30min_R1 4 SPEPGQTWTR 10 0 Q09666;E9PJZ0;E9PKR9;E9PJC6;E9PLK4;Q09666-2 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(1)PEPGQTWTR;S(1)PEPGQTWTR;S(1)PEPGQTWTR;S(1)PEPGQTWTR 166.24 0.00011916 536286000.0 113710.7 202789.8 195057.5 173758.30000000002 234318.3 148928.7 165734.1 231226.6 151816.2 95870.2 True False 112089.16456601162 202320.25267746823 179020.62529372415 186537.06502269636 220536.15828150266 142559.36667075614 174315.00075482044 241970.2319702048 134717.06086054075 112441.23633098818 0.9968688376572081 1.7993421210872074 1.5921260841240596 1.6589737991993938 1.9613459036711438 1.267856627359651 1.5502764505514441 2.151970574726944 1.198110811090517 1.0 16.778811696294916 S(ph)PEPSPR ddPTM_PC-9_AZD4547_30min_R2 1 SPEPSPR 7 0 G5E9Y3;Q8WWN8;Q05CH1 G5E9Y3 ARAP3 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 1 S(1)PEPSPR 90.601 0.015819 3869000.0 21346.0 22660.0 39146.0 39496.0 32986.0 29424.0 20811.0 27450.0 25152.0 24951.0 True False 28133.583975617865 29984.401859548398 38626.898462457975 30390.80740711713 28406.463279805896 27584.11262856647 22663.13868375096 23208.23323824799 26481.483371174298 24077.473084493347 1.1684608213200238 1.2453300956593862 1.6042754290247725 1.2622091737147354 1.1797942076446781 1.1456398489894484 0.9412590185116534 0.9638982112784429 1.0998447917788021 1.0 14.555396369663528 -6.686362844844853 1.6072574301335987 1.0025219212052534 1.3332303844379345 0.5922821664456415 0.11622065094392667 0.27005054522182453 1.444875242019751 0.05167035691974679 0.049880609431524545 2.058909014849027e-07 6.686362844844853 0.3307084632326811 S(ph)PERPTGDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPERPTGDLR 10 1 Q5T200-2;Q5T200;Q5T9K0 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 S(0.974)PERPT(0.026)GDLR 54.772 0.043814 23304000.0 39299.0 39179.0 44701.0 41621.0 42486.0 32226.0 31586.0 41031.0 35900.0 31635.0 True False 45951.54450936935 43068.43219500939 45766.84136948656 39289.1103071026 34161.17328830289 30536.011829369272 28593.945417163166 39953.97972593805 36424.96958387263 37370.17507747779 1.2296315019691564 1.15248141347258 1.2246889738835947 1.0513493775623575 0.9141293348901408 0.8171225252774552 0.7651541732914205 1.0691408226775332 0.9747069557034317 1.0 15.189599702241008 -6.0075234826927035 2.846310628883029 0.9140390759041177 1.197500164072031 0.6847057566541808 0.08451758691101655 0.16314146130520493 2.6782048479937526 0.028006224754663446 0.04151044419723853 9.82825729293361e-07 6.0075234826927035 0.2834610881679134 S(ph)PESDRPR ddPTM_PC-9_AZD4547_30min_R2 2 SPESDRPR 8 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 S(0.998)PES(0.002)DRPR;S(0.99)PES(0.01)DRPR 82.241 0.0079023 36180000.0 19025.2 29726.0 33006.0 24978.0 21605.3 25853.0 34235.0 30055.0 25130.0 28861.0 True False 25074.817851256663 39334.34817638728 32568.318874262724 19219.708006253077 18605.77702962439 24236.407823080786 37281.84867801711 25410.690345192834 26458.320496088203 27850.58517460472 0.9003336085778509 1.4123347114535285 1.1693944191865606 0.6901006885764963 0.6680569515138908 0.8702297517676761 1.338637893756437 0.9123934088237156 0.9500094999875968 1.0 14.765420020207435 -5.623436966390956 10.942219040860401 0.9200289732232018 1.1898392920451133 0.21776267926005832 0.2085066769612758 0.5441347017802443 54.73419804035502 0.05994912464991649 0.10387218709391381 2.37992369860737e-06 5.623436966390956 0.26981031882191153 S(ph)PESDRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPESDRPR 8 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 S(0.99)PES(0.01)DRPR 92.23899999999999 0.0038332 22558000.0 16145.0 18581.0 17537.0 13908.0 16202.0 12843.0 14184.0 4614.8 10500.0 12270.0 True False 18878.02962171475 20425.598882449012 17955.148589442855 13128.779850344376 13027.334407030172 12169.490471190635 12840.388836732813 4493.666389784775 10653.542635951597 14494.45387073344 1.3024312464667906 1.4092009995417267 1.2387599249735857 0.9057795462617206 0.8987806317652568 0.8395963435202434 0.8858829005389129 0.31002660947841487 0.7350082128629047 1.0 13.823213355389065 -5.901630950285756 0.8545370525576698 0.694079514157011 1.4319944566563794 0.6490467753099489 0.1774825442184169 0.43856899308904645 0.619700439349056 0.08276112574414046 0.2232137409446132 1.2542065072545133e-06 5.901630950285756 0.7379149424993684 S(ph)PESDRPR ddPTM_PC-9_Lapatinib_30min_R1 1 SPESDRPR 8 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 S(1)PESDRPR 87.696 0.005441 21886000.0 10584.0 12000.0 15009.0 9580.0 13670.0 12747.0 21074.0 15787.0 11740.0 4812.9 True False 10433.070219132118 11972.214737277802 13775.017956415455 10284.545157943166 12865.957476254056 12201.840524708326 22165.10860412608 16520.521653276977 10417.717572319336 5644.803352213868 1.8482610585611123 2.120926804754385 2.4403007681415425 1.8219492365326795 2.2792569861991883 2.161605952122817 3.926639640233529 2.926677976620337 1.8455412743888682 1.0 12.462707607426976 -7.041913606771303 24.99970106000258 2.6508213080574947 2.117804756892935 0.005897661312828317 0.7326500381088156 1159.5511501905576 691619.8623955887 0.27284281567412705 0.21136400131148775 9.080011388466644e-08 7.041913606771303 -0.5330165511645597 S(ph)PESQVIGENTK ddPTM_PC-9_Lapatinib_30min_R1 2 SPESQVIGENTK 12 0 O95218-2 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 S(0.995)PES(0.005)QVIGENTK;S(0.997)PES(0.003)QVIGENTK 128.85 0.001307 0.0 10944.8 18134.9 15827.1 13110.5 19718.2 19957.9 23598.0 19812.9 14457.8 18848.1 True False 10788.725144969492 18092.909753254928 14525.856932372775 14074.689905345904 18558.414243472773 19104.347141137234 24819.788974099225 20733.47966454751 12829.410316616579 22105.968971485403 0.48804579246835644 0.8184626413161559 0.6571011183047325 0.6366918330293919 0.8395205054078997 0.8642166812854947 1.1227641279201284 0.9379131804306668 0.5803595550670182 1.0 14.432148352914876 -6.423176541160256 2.8334608692476397 0.9095129542159178 0.6618000671478883 0.38867877137198437 0.14867230671573384 0.3084663016581426 4.80402416408926 0.05074689120417234 0.0575097126309592 3.774187386270281e-07 6.423176541160256 -0.24771288706802952 S(ph)PETALEAFK ddPTM_PC-9_AZD4547_30min_R2 4 SPETALEAFK 10 0 Q68DA7-3;Q68DA7-5 Q68DA7-3 1 S(1)PETALEAFK;S(1)PETALEAFK;S(0.997)PET(0.003)ALEAFK;S(1)PETALEAFK 134.98 0.00011253 13655600.0 47328.5 56500.9 59509.9 49881.7 55067.6 69750.9 56357.0 74384.0 59891.4 54028.0 True False 62377.978506044696 74763.71098968043 58720.75984292211 38382.244729582606 47422.41427596675 65389.36519657 61372.66382202456 62889.66197427466 63057.13713328361 52136.496164843345 1.1964359535942 1.433999529874335 1.1262889561519607 0.7361876526613329 0.9095819198518486 1.2541956212366898 1.177153593674163 1.20625025846448 1.209462502695075 1.0 15.67000600930707 -5.429103932432686 6.994901543314902 1.073161158098792 1.310745936422889 0.26794754705354407 0.1593663766590349 0.3692394273697927 23.670870123829353 0.04648388339160749 0.09734992734744836 3.723025986402987e-06 5.429103932432686 0.23758477832409697 S(ph)PETALEAFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPETALEAFK 10 0 Q68DA7-3;Q68DA7-5 Q68DA7-3 1 S(1)PETALEAFK;S(0.999)PET(0.001)ALEAFK;S(1)PETALEAFK;S(1)PETALEAFK 131.83 0.00016686 11396100.0 48750.0 61130.0 47914.0 43287.5 55355.0 45293.0 55730.0 35008.399999999994 35540.600000000006 37819.7 True False 57002.41214361062 67198.58240590426 49056.4514748569 40862.24171496853 44508.58511919239 42917.75534623043 50450.85094974048 34089.4665944659 36060.31403879061 44676.1122294195 1.2759035936451555 1.5041278001279077 1.0980465628464626 0.9146328916252584 0.9962501860196152 0.9606421240469715 1.1292578613525435 0.7630356558200642 0.8071497773489043 1.0 15.447216025724867 -5.460263666932125 3.8415845027790794 0.9421123807648076 1.3863861554526535 0.7246013132277168 0.10990670217260022 0.11688392529745503 3.3790802522745347 0.03071768786694597 0.06642501990120026 3.465264050085707e-06 5.460263666932125 0.4442737746878459 S(ph)PETALEAFK ddPTM_PC-9_Lapatinib_30min_R1 4 SPETALEAFK 10 0 Q68DA7-3;Q68DA7-5 Q68DA7-3 1 S(1)PETALEAFK;S(1)PETALEAFK;S(1)PETALEAFK;S(1)PETALEAFK 168.22 0.00013692 12149000.0 52480.6 73571.0 56630.0 47008.5 67847.0 67204.0 67898.0 70375.0 62243.0 48719.5 True False 51732.21702023666 73400.65086968878 51974.09999812161 50465.661905759014 63856.37285233427 64329.84158017564 71413.42621253451 73644.8794165686 55232.5378921527 57140.60066034684 0.9053495486990327 1.2845621155786295 0.9095826679713123 0.8831839589110243 1.1175306544624388 1.1258166844020916 1.2497843107570343 1.2888362839292837 0.9666075829420139 1.0 15.802228581472123 -6.497476165335681 21.378669465216387 1.1486169244221307 1.0089307697533991 0.15688011177162264 0.1407176479425611 215.54729965033366 181402.86922219227 0.04407322422494812 0.04965499052865191 3.1807082450789325e-07 6.497476165335681 -0.13968615466873158 S(ph)PFEGAVTESQSLFSDNFR ddPTM_PC-9_AZD4547_30min_R2 3 SPFEGAVTESQSLFSDNFR 19 0 O95628-3;O95628-2;O95628;O95628-8;O95628-4;O95628-7;O95628-9;O95628-10;O95628-6;O95628-5 O95628-3 CNOT4 CCR4-NOT transcription complex subunit 4 1 S(1)PFEGAVTESQSLFSDNFR;S(1)PFEGAVTESQSLFSDNFR;S(1)PFEGAVTESQSLFSDNFR 223.54 4.7031999999999993e-35 35766700.0 5864.58 9848.2 13932.1 15903.3 16375.0 18727.9 13587.9 20446.1 14586.3 16528.6 True False 7729.394449158105 13031.438057952531 13747.351250927568 12237.039888535695 14101.613903074685 17556.84145243781 14797.196776749784 17286.625049637238 15357.302039478367 15949.938744914294 0.4846033939548925 0.8170211977840768 0.8619062098474184 0.7672154786448648 0.8841171197332055 1.1007466381672395 0.9277274987321148 1.0838051058440052 0.9628439510073421 1.0 13.961263262939088 -4.272230994537041 0.48203388330117103 1.019313636622924 3.772230291785465e-14 0.7496546533984891 0.08467023490543142 3.905540944153037 0.48502596515248975 0.054600704512837536 2.502835946718718 5.342801084595451e-05 4.272230994537041 -1.0193136366228863 down S(ph)PFEGAVTESQSLFSDNFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPFEGAVTESQSLFSDNFR 19 0 O95628-3;O95628-2;O95628;O95628-8;O95628-4;O95628-7;O95628-9;O95628-10;O95628-6;O95628-5 O95628-3 CNOT4 CCR4-NOT transcription complex subunit 4 1 S(1)PFEGAVTESQSLFSDNFR;S(1)PFEGAVTESQSLFSDNFR;S(1)PFEGAVTESQSLFSDNFR;S(1)PFEGAVTESQSLFSDNFR 213.01 1.3430999999999998e-27 50141800.0 14940.199999999999 18378.2 22957.1 25660.9 29506.3 22999.5 27846.300000000003 24939.100000000002 20911.0 21423.6 True False 17469.28077759941 20202.666238707523 23504.484329286566 24223.202966760287 23724.75232774682 21793.365731694248 25208.496874246517 24284.475050160672 21216.783815274648 25307.529090875712 0.6902799840659958 0.7982867930789546 0.9287546107281089 0.9571540105625577 0.9374582655839151 0.8611415857090352 0.9960868476620699 0.9595751115392814 0.8383585666972155 1.0 14.62727903585786 -5.021015994632838 2.21187348309612 0.9349732310953113 0.6786901880722535 0.7251263482530663 0.04912846635682673 0.20371633404381023 1.6339847838361097 0.013080323601071985 0.08467630446026592 9.527610741369022e-06 5.021015994632838 -0.2562830430230578 S(ph)PFEGAVTESQSLFSDNFR ddPTM_PC-9_Lapatinib_30min_R1 4 SPFEGAVTESQSLFSDNFR 19 0 O95628-3;O95628-2;O95628;O95628-8;O95628-4;O95628-7;O95628-9;O95628-10;O95628-6;O95628-5 O95628-3 CNOT4 CCR4-NOT transcription complex subunit 4 1 S(1)PFEGAVTESQSLFSDNFR;S(1)PFEGAVTESQSLFSDNFR;S(0.992)PFEGAVT(0.007)ES(0.001)QSLFSDNFR;S(1)PFEGAVTESQSLFSDNFR 166.21 8.6247e-08 25963800.0 14165.3 13031.0 15748.8 13554.5 18645.8 17169.7 15011.5 15131.7 16048.7 11023.869999999999 True False 13963.300224402123 13000.827520122251 14453.994456126029 14551.343146486493 17549.09070305324 16435.391955525563 15788.722018166382 15834.774022986703 14241.12640569688 12929.33124111655 1.079970801583105 1.005529773943631 1.1179228211093315 1.125452111568755 1.3573084621148384 1.2711710798513225 1.2211553500893138 1.224717174282809 1.1014588566196442 1.0 13.658360034428753 -5.782603653864169 2.484634620440802 1.2124177595161927 1.05043634894628 0.2549034289388564 0.09478055315130246 0.32154674778265463 4.048442679096192 0.02774040472398818 0.049923493285497764 1.6496672252143638e-06 5.782603653864169 -0.16198141056991266 S(ph)PFEHSVEHK ddPTM_PC-9_AZD4547_30min_R2 2 SPFEHSVEHK 10 0 O14646;O14646-2 O14646 CHD1 Chromodomain-helicase-DNA-binding protein 1 1 S(0.987)PFEHS(0.013)VEHK;S(1)PFEHSVEHK 162.93 9.0833e-14 0.0 89869.0 96807.0 159975.0 130790.0 128184.0 169462.0 132444.0 191663.0 155030.0 136990.0 True False 118445.47260867585 128097.9695859355 157853.6269741918 100638.38618535681 110387.86421689938 158865.51435094237 144231.25942197483 162045.8873275895 163224.56929998228 132194.0217965109 0.8959971941167014 0.9690148453393713 1.194105639793449 0.7612930208014371 0.8350442986508255 1.20176020210269 1.0910573523815859 1.2258185742849266 1.2347348774306706 1.0 17.012297409833536 -6.771482320652965 24.999720721656168 1.1610618419827854 0.9383765794048715 0.44017014188816006 0.12340475300869538 205.95546951502538 512678.4708074026 0.04481027735749181 0.039970263787042194 1.6924571399194302e-07 6.771482320652965 -0.22268526257791388 S(ph)PFEHSVEHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPFEHSVEHK 10 0 O14646;O14646-2 O14646 CHD1 Chromodomain-helicase-DNA-binding protein 1 1 S(0.999)PFEHS(0.001)VEHK;S(0.998)PFEHS(0.002)VEHK 129.74 0.00013387 15018800.0 69114.0 114819.0 121037.0 122446.0 122193.0 99393.0 107663.0 82178.0 94781.0 88576.0 True False 80813.63513627712 126217.47150766414 123922.98111537872 115585.74759528812 98250.15881979006 94180.65610862355 97464.38122738022 80020.91457478814 96166.99281696463 104634.12763276999 0.7723449028017451 1.2062744189032122 1.1843457189255309 1.104665850523976 0.9389876997361178 0.900095009528492 0.9314779358551817 0.7647687841928036 0.9190786504617107 1.0 16.674993954475525 -6.383306171472223 3.659138294180217 0.8922468771320086 1.0851182444348608 0.27658138079145833 0.12380219524427559 0.28538161884325414 6.882555382785189 0.03991299657899177 0.04566174664904405 4.137079137554891e-07 6.383306171472223 0.19287136730285226 S(ph)PFEHSVEHK ddPTM_PC-9_Lapatinib_30min_R1 2 SPFEHSVEHK 10 0 O14646;O14646-2 O14646 CHD1 Chromodomain-helicase-DNA-binding protein 1 1 S(0.985)PFEHS(0.015)VEHK;S(0.996)PFEHS(0.004)VEHK 100.02 0.0023509 20226100.0 91050.0 129572.0 162620.0 103787.0 167033.0 169570.0 152527.0 182127.0 174367.0 113860.0 True False 89751.61030347494 129271.98399487966 149250.0113313529 111419.84220328268 157208.4473395129 162317.88638697672 160424.10173965726 190589.28530730205 154727.95229408896 133540.5492910866 0.6720925649919097 0.9680354370349153 1.1176381415507242 0.8343521334513456 1.1772337928372298 1.2154951230068882 1.2013137776599296 1.4272015977099421 1.1586589475292548 1.0 17.0269183540165 -4.148167481662043 0.4787816842061828 1.2299117755178102 1.922399738746462e-13 0.5362135831435197 0.13894655269114464 6.418934487872965 0.7197356842803477 0.08870778785077466 5.054495966015529 7.109392935989531e-05 4.148167481662043 -1.2299117755176179 S(ph)PFLKPDER ddPTM_PC-9_AZD4547_30min_R2 5 SPFLKPDER 9 1 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 S(1)PFLKPDER;S(1)PFLKPDER;S(1)PFLKPDER;S(1)PFLKPDER;S(1)PFLKPDER 96.113 0.0035848 106856900.0 450912.0 501279.0 551305.0 496549.0 544599.0 630559.0 533348.0 607351.0 550538.0 504443.0 True False 594292.6364477554 663307.6337048793 543994.3354837118 382077.29965557554 468990.8293130125 591130.0460493554 580814.9387680189 513498.8584875453 579638.3147343978 486782.6041104992 1.2208584107760176 1.3626362735721531 1.11753035315992 0.7849033560961934 0.963450265791651 1.2143614851018165 1.1931711073146205 1.0548833383762035 1.190753962528251 1.0 18.892918086588807 -5.401074891735893 5.64978937894825 1.059932124745496 1.2881091828401596 0.3494807771547579 0.12567741999092574 0.26342729905141693 10.986441743902011 0.03621686390457047 0.07683978218100967 3.971230618390223e-06 5.401074891735893 0.2281770580946636 S(ph)PFLKPDER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPFLKPDER 9 1 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 S(1)PFLKPDER;S(1)PFLKPDER;S(1)PFLKPDER;S(1)PFLKPDER 78.513 0.010140999999999999 72432600.0 345043.0 392654.0 380161.0 381627.0 448955.0 309971.0 378283.0 273285.0 295538.0 297222.0 True False 403451.96499010926 431634.09416011727 389225.48000862164 360245.6764414274 360985.49060043343 293715.57508724113 342449.2957082489 266111.5583193926 299859.68414703454 351105.99579194246 1.1490887932007456 1.2293555203651205 1.1085697329967215 1.0260311152729527 1.0281382116138664 0.8365438887614166 0.975344482328854 0.757923708249871 0.8540431884983378 1.0 18.421547107583542 -6.118464580257816 0.9430297814793575 0.8676977679018529 1.199484379559967 0.717808584383794 0.07421769102865214 0.2914385280378092 0.5387310164487306 0.032718326647115104 0.06213647620374645 7.612642228776513e-07 6.118464580257816 0.3317866116581141 S(ph)PFLKPDER ddPTM_PC-9_Lapatinib_30min_R1 4 SPFLKPDER 9 1 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 S(1)PFLKPDER;S(1)PFLKPDER;S(1)PFLKPDER;S(1)PFLKPDER 106.4 0.0012135 109485700.0 497471.0 545746.0 507128.0 481338.0 510057.0 527956.0 491564.0 489040.0 469002.0 424456.0 True False 490376.9723149911 544482.3586675342 465433.89341068966 516737.20221649675 480056.45007064525 505376.5526055466 517014.7786788757 511762.58372829336 416178.05594999326 497822.654047932 0.9850435056090798 1.093727563902927 0.9349391588070963 1.0379945509003365 0.9643121825959006 1.0151738746643846 1.0385521319186406 1.0280017985662404 0.8359966196112929 1.0 18.925272357907545 -8.23097369859219 24.951399680686645 0.9179982458806952 1.0125977991195678 0.31619456327238027 0.05542088503884847 629.5075412288961 515568.4185709993 0.034547430089589264 0.013054347620891967 5.875249326846893e-09 8.23097369859219 0.09459955323887259 S(ph)PFSVAVSPSLDLSK ddPTM_PC-9_AZD4547_30min_R2 1 SPFSVAVSPSLDLSK 15 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 S(0.889)PFS(0.109)VAVS(0.002)PSLDLSK 156.24 0.00020761 5601100.0 24736.0 22161.0 26893.0 41359.0 30528.0 28873.0 22972.0 33928.0 27527.0 32860.0 True False 32601.533459237493 29324.109868025225 26536.381248425954 31824.3215401802 26289.714151637487 27067.566745670207 25016.463497339268 28685.207187878965 28982.021022515713 31709.581401805586 1.0281287868839895 0.924771270123278 0.8368568765437862 1.0036184690337187 0.8290779313201692 0.8536084536306412 0.7889244320303388 0.9046227013973004 0.9139830846478926 1.0 14.952631212099202 -4.820523388127805 3.272270308812752 0.8843891762524663 1.0418613695417822 0.2699260389679483 0.06662056904203763 0.37022922085865356 6.387538348093138 0.016651591943852042 0.141250523012683 1.5117382852932878e-05 4.820523388127805 0.15747219328931594 S(ph)PGAFDMSGVR ddPTM_PC-9_AZD4547_30min_R2 4 SPGAFDMSGVR 11 0 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 S(1)PGAFDMSGVR;S(1)PGAFDMSGVR;S(1)PGAFDMSGVR;S(1)PGAFDMSGVR 132.5 0.0001051 60636400.0 78446.7 96393.0 97955.9 95465.5 99952.5 115909.2 111985.9 147959.0 121178.8 98944.7 True False 103391.11880727552 127550.15218214698 96656.94076275203 73457.4039022722 86075.82068073709 108661.37940072856 121952.42815456558 125095.33630957874 127584.06397657664 95480.676169423 1.082848623985612 1.335873993558856 1.0123193994902366 0.76934314721366 0.9014999069340719 1.1380457675846098 1.277247219512465 1.3101639130373024 1.3362291627490017 1.0 16.542921162797995 -7.016275216168808 4.970020377005419 1.2525248849044643 1.0224329728093906 0.27451658526809997 0.15992023805902125 0.26022591148798024 18.028685833920605 0.06631621078908984 0.053970746941987495 9.632184303264069e-08 7.016275216168808 -0.23009191209507374 S(ph)PGAFDMSGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPGAFDMSGVR 11 0 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 S(1)PGAFDMSGVR;S(0.998)PGAFDMS(0.002)GVR 84.18799999999999 0.010694 33892000.0 54666.0 90891.0 84004.0 71027.0 102768.0 69129.0 109808.0 73837.0 78162.0 83294.0 True False 63919.87409728446 99914.05780230711 86006.97394694388 67047.58746264101 82631.34812626083 65503.753545350686 99406.19129892506 71898.85698676817 79304.97138202356 98394.54284505878 0.6496282440982388 1.0154430816314794 0.8741030900705385 0.6814157119284592 0.8397960469858562 0.665725472687027 1.0102815504256095 0.730719965841874 0.8059895304041867 1.0 16.586290682627244 -10.72976063798789 6.529628229381763 1.0000012400254104 0.812846852994599 0.17353101592364206 0.1252418801308752 2.1613602696945377e-06 2.624474133477095e-07 0.11593006684300883 0.028116984786951675 1.863113711469944e-11 10.72976063798789 -0.18715438703081133 S(ph)PGAFDMSGVR ddPTM_PC-9_Lapatinib_30min_R1 4 SPGAFDMSGVR 11 0 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 S(1)PGAFDMSGVR;S(1)PGAFDMSGVR;S(1)PGAFDMSGVR;S(1)PGAFDMSGVR 143.55 0.00015341 46881900.0 49898.1 63033.4 62842.7 52193.4 78257.1 72631.2 80988.7 85276.4 89102.5 53365.9 True False 49186.543943809156 62887.45003506059 57676.01578583714 56031.87674807832 73654.17123737828 69524.93288759665 85181.89860524754 89238.6528608037 79066.83815907872 62590.124709408025 0.7858515088789374 1.0047503552203 0.9214874719233106 0.8952191261516383 1.1767698431555802 1.1107971618587658 1.3609478971439677 1.425762502872759 1.2632478130722442 1.0 15.933647430371348 -6.515286408202286 1.4276896933841785 1.2861554631988696 0.9002399559947755 0.6054436579471983 0.1253341368034319 0.2568739682926249 1.0750661220681859 0.05074631181100487 0.05668440715251057 3.0529071202755636e-07 6.515286408202286 -0.3859155072040942 S(ph)PGALETPSAAGSQGNTASQGK ddPTM_PC-9_AZD4547_30min_R2 4 SPGALETPSAAGSQGNTASQGK 22 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 S(1)PGALETPSAAGSQGNTASQGK;S(0.991)PGALET(0.009)PSAAGSQGNTASQGK;S(1)PGALETPSAAGSQGNTASQGK;S(1)PGALETPSAAGSQGNTASQGK 260.15 6.998399999999999e-74 170419500.0 129518.0 132455.0 161415.0 149157.0 158334.0 167597.0 154824.0 185563.0 161426.0 147206.0 True False 170702.02985824374 175268.48845130124 159274.53163331252 114771.15810267799 136352.05714378174 157117.1330957674 168603.03606617008 156888.5021635338 169958.64880228954 142052.36274601938 1.20168384783186 1.2338301529321984 1.1212381727017473 0.8079496594356655 0.9598718001443635 1.1060508256147972 1.1869076501572988 1.1044413421270611 1.1964506997054658 1.0 17.11606330239944 -5.518829911533268 24.998158168162686 1.0527490635686885 1.2077013287008185 0.27309025489692873 0.10780360831065557 239.07377624016954 1476078.5837424512 0.03262030294213458 0.05823954002104633 3.0280991302364267e-06 5.518829911533268 0.15495226513213 S(ph)PGALETPSAAGSQGNTASQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SPGALETPSAAGSQGNTASQGK 22 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 S(1)PGALETPSAAGSQGNTASQGK;S(1)PGALETPSAAGSQGNTASQGK;S(1)PGALETPSAAGSQGNTASQGK;S(1)PGALETPSAAGSQGNTASQGK;S(0.847)PGALET(0.146)PS(0.007)AAGSQGNTASQGK;S(1)PGALETPSAAGSQGNTASQGK 284.41 2.5253999999999993e-116 158718400.0 221751.2 239939.0 263030.0 235397.0 289328.0 230146.5 269207.0 221471.0 231267.0 181947.8 True False 259289.2983741592 263758.55821839086 269301.6327468303 222208.46925737083 232636.25535842613 218077.2123902419 243705.7640701017 215657.62091792087 234648.84236082068 214933.4958420078 1.2063698929679916 1.2271635799953355 1.2529532993069965 1.0338475554350572 1.0823638932920496 1.014626461715139 1.1338659110129752 1.0033690657339205 1.0917276594863796 1.0 17.713530808386608 -5.762119438626342 24.99999772573242 1.0547344445748585 1.2286624154550752 0.7937103985218211 0.04142718250204102 7.175201195176814 263791.34307609225 0.01064825389078656 0.01692483670123036 1.7293406946816692e-06 5.762119438626342 0.1739279708802166 S(ph)PGALETPSAAGSQGNTASQGK ddPTM_PC-9_Lapatinib_30min_R1 4 SPGALETPSAAGSQGNTASQGK 22 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 S(1)PGALETPSAAGSQGNTASQGK;S(1)PGALETPSAAGSQGNTASQGK;S(1)PGALETPSAAGSQGNTASQGK;S(0.999)PGALET(0.001)PSAAGSQGNTASQGK 273.42 4.149399999999999e-101 189292000.0 162340.0 162564.0 162192.0 157479.0 178363.0 156739.0 162364.0 138347.0 172171.0 130770.0 True False 160025.00183049028 162187.59304590244 148857.19983922545 169060.53099454366 167872.03901515008 150035.63834645483 170770.4134668464 144775.10668055454 152779.28893899434 153373.42025992766 1.0433685416892309 1.0574687111432808 0.9705540867964709 1.102280504066679 1.0945314952920204 0.9782375465852156 1.1134289968720485 0.9439386983428991 0.996126243256971 1.0 17.226688958700507 -7.777199213421679 24.99995737308495 0.9775243562791193 1.0493339327346671 0.3233219655824052 0.04721891070470939 293.28705059383725 465236.9669803176 0.024950407927418216 0.012049838612174037 1.670324251042647e-08 7.777199213421679 0.07180957645554786 S(ph)PGAPCQECSR ddPTM_PC-9_AZD4547_30min_R2 3 SPGAPCQECSR 11 0 Q9NWF9-3;Q9NWF9;Q9NWF9-1 Q9NWF9-3 RNF216 E3 ubiquitin-protein ligase RNF216 1 S(1)PGAPCQECSR;S(1)PGAPCQECSR;S(1)PGAPCQECSR 102.33 0.0033633 47091200.0 5750.299999999999 3410.73 6148.9 12697.099999999999 10973.6 7492.8 6929.09 8253.3 6505.6 4808.5 True False 7578.775786329776 4513.181772039607 6067.3615683801145 9769.979763239484 9450.105058123994 7024.274031515867 7545.765586574023 6977.94212696656 6849.47273455437 4640.155878593494 1.6333019804987725 0.97263581011585 1.307577100237251 2.1055283526813158 2.0365921545266006 1.513801306529607 1.626187952302427 1.5038163177142416 1.4761298787726405 1.0 12.179957555854685 -8.926843180025646 1.2225728773436741 1.0004564162783465 1.5942919596074114 0.24948583269620572 0.3064283923846311 2.4628547036875608 5.542945740289523 0.3290167624203022 0.09967882337870677 1.1834688189160317e-09 8.926843180025646 0.593835543329065 S(ph)PGAPCQECSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGAPCQECSR 11 0 Q9NWF9-3;Q9NWF9;Q9NWF9-1 Q9NWF9-3 RNF216 E3 ubiquitin-protein ligase RNF216 1 S(1)PGAPCQECSR 99.161 0.0046767 15492000.0 1836.0 0.0 724.27 2011.6 4153.2 3428.9 1188.6 2153.5 2066.4 3456.4 True False 2146.7985373470583 0.0 741.539343609271 1898.8965736951936 3339.410273995661 3249.082447766532 1076.007203281205 2096.972906821857 2096.6171907552753 4083.017959152654 0.5257871894819149 0.0 0.18161549888532996 0.4650718151847832 0.8178779293659258 0.795755120420977 0.263532321935833 0.5135840517480948 0.513496930880604 1.0 11.995420197932594 -5.916365554912183 4.226179663534738 0.6166216093442101 0.2150473277731457 0.39663954551129044 0.22612553373517727 0.2295310598959236 7.721718010641652 0.06606647939295557 0.10045394134910501 1.2123679449539454e-06 5.916365554912183 -0.40157428157106434 S(ph)PGAPCQECSR ddPTM_PC-9_Lapatinib_30min_R1 3 SPGAPCQECSR 11 0 Q9NWF9-3;Q9NWF9;Q9NWF9-1 Q9NWF9-3 RNF216 E3 ubiquitin-protein ligase RNF216 1 S(1)PGAPCQECSR;S(1)PGAPCQECSR;S(1)PGAPCQECSR 133.88 5.6067e-05 35623300.0 7520.4 7948.699999999999 4734.21 5877.9 8551.31 5779.7 6751.4 8540.7 9106.9 6462.75 True False 7413.157716927545 7930.295273516673 4344.981528379076 6310.180374099596 8048.338758322317 5532.515704138755 7100.954457146095 8937.532101358247 8081.185022091571 7579.827726426925 0.9780113723537162 1.0462368749975477 0.5732295884813292 0.8324965423817314 1.0618102480432288 0.7298999269930296 0.9368226710996019 1.1791207431004944 1.0661436267102316 1.0 12.88794934400121 -7.588253890498778 6.150882882215651 1.0892019622618967 0.8686789932194805 0.3026019715987279 0.1433092435514615 0.2537758907373106 17.818845067070274 0.07020275607042377 0.04011661340753496 2.5807510309382048e-08 7.588253890498778 -0.2205229690424162 S(ph)PGAPGPLTLK ddPTM_PC-9_AZD4547_30min_R2 4 SPGAPGPLTLK 11 0 Q15942;Q15942-2;H0Y2Y8;C9JJK5 Q15942 ZYX Zyxin 1 S(1)PGAPGPLTLK;S(1)PGAPGPLTLK;S(1)PGAPGPLTLK;S(1)PGAPGPLTLK 136.01 6.8179e-05 1088280000.0 465057.0 379892.0 543912.0 672100.0 591590.0 525016.0 443226.0 577586.0 439194.0 479166.0 True False 612935.4522134797 502684.659807041 536699.3714942121 517157.7288414879 509457.94008671417 492186.6665239083 482672.2553574655 488333.3553058904 462408.8982076783 462390.54418677994 1.3255795558956933 1.0871430355288245 1.1607057675414216 1.1184435653869795 1.1017914325707354 1.064439298579368 1.0438627290840379 1.0561058426589083 1.0000396937634843 1.0 18.81875236969252 -1.5228787452803376 0.3013609586776275 1.0137769869052298 3.1669837739197857 0.7695506617139473 0.04326838469043103 26.449887194422615 0.37707566288534244 0.042583203055923544 30.749600610542256 0.029999999999999995 1.5228787452803376 2.1532067870145557 S(ph)PGAPGPLTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 SPGAPGPLTLK 11 0 Q15942;Q15942-2;H0Y2Y8;C9JJK5 Q15942 ZYX Zyxin 1 S(1)PGAPGPLTLK;S(1)PGAPGPLTLK;S(1)PGAPGPLTLK;S(1)PGAPGPLTLK;S(1)PGAPGPLTLK;S(1)PGAPGPLTLK;S(1)PGAPGPLTLK 106.79 0.0023906999999999995 795538900.0 373155.0 394075.0 395126.0 419126.0 479722.0 466067.0 571523.0 496345.0 457414.0 390035.0 True False 436322.7713528003 433196.1616490558 404547.30236369924 395643.72904482577 385723.91781319166 441625.6260559373 517384.2039718018 483316.4696709989 464102.8144077307 460745.25798463775 0.9469935149443215 0.9402075314761015 0.878028141045323 0.8587038546537085 0.8371739288221878 0.9585028134367952 1.122928983002257 1.0489884839728807 1.00728722947205 1.0 18.813609792073045 -7.020587163374264 6.580339672155035 1.0483118136818281 0.8924892131351081 0.7284095136256107 0.04389080939206287 0.09284147381617369 16.495193046713094 0.01750016816208787 0.01414768346104013 9.537023145417795e-08 7.020587163374264 -0.15582260054672004 S(ph)PGAPGPLTLK ddPTM_PC-9_Lapatinib_30min_R1 4 SPGAPGPLTLK 11 0 Q15942;Q15942-2;H0Y2Y8;C9JJK5 Q15942 ZYX Zyxin 1 S(1)PGAPGPLTLK;S(1)PGAPGPLTLK;S(1)PGAPGPLTLK;S(1)PGAPGPLTLK 124.21 0.00052314 728670000.0 552348.0 439769.0 509147.0 449004.0 617617.0 590215.0 592712.0 547705.0 663890.0 571644.0 True False 544471.4162317814 438750.74189982744 467286.89902425633 482025.25199343427 581289.9823417413 564972.8803083639 623399.7271979114 573153.3737954063 589115.7171283716 670451.9037322503 0.8120961596213467 0.6544104647289444 0.696973036280423 0.718955751054045 0.8670122034195663 0.8426747350008119 0.9298202059351157 0.8548761970915354 0.8786845318044456 1.0 19.35477431553634 -6.315593502817167 2.795562168082489 0.8923866468617803 0.711205528944893 0.7047504380966719 0.055510072860773585 0.15082778566841867 2.3310379949923856 0.017534790049793893 0.021196024034872796 4.835111540173306e-07 6.315593502817167 -0.1811811179168873 S(ph)PGASNFSTLPK ddPTM_PC-9_AZD4547_30min_R2 1 SPGASNFSTLPK 12 0 Q9Y4E8 Q9Y4E8 USP15 Ubiquitin carboxyl-terminal hydrolase 15 1 S(1)PGASNFSTLPK 89.01299999999999 0.027417 0.0 13173.0 13822.0 16034.0 16229.0 14622.0 15522.0 14348.0 20329.0 18741.0 16038.0 True False 17361.739984578562 18289.69119605816 15821.378683570505 12487.65478555054 12591.9876940921 14551.406886236018 15624.944204240977 17187.62016394692 19731.61099949021 15476.514501587279 1.121812019288835 1.1817706883667094 1.0222830652178083 0.8068777232929158 0.8136190931621368 0.9402250671327591 1.0095906415258085 1.1105614356633173 1.27493894038393 1.0 13.917792975226 -9.694580813944656 9.510118624918526 0.9999924708155147 1.0214695204947954 6.011973518871283e-05 0.1428086370289982 0.0 0.0 0.15522919946907662 0.03764861091712211 2.0203154547238804e-10 9.694580813944656 0.02147704967928077 S(ph)PGASNFSTLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPGASNFSTLPK 12 0 Q9Y4E8 Q9Y4E8 USP15 Ubiquitin carboxyl-terminal hydrolase 15 1 S(1)PGASNFSTLPK;S(1)PGASNFSTLPK;S(1)PGASNFSTLPK;S(1)PGASNFSTLPK 150.11 7.3423e-05 94879100.0 158569.0 191389.0 193977.0 181448.0 221303.0 185236.0 211351.0 157064.0 188622.0 156596.0 True False 185411.59981949077 210388.8350741637 198602.1473418695 171282.05682235298 177940.26578687763 175521.89807065847 191330.30323126854 152941.236423064 191380.23991223465 184985.6151867464 1.0023027986922892 1.1373253799316898 1.0736086000058813 0.9259209514720406 0.9619140688709424 0.9488407944232089 1.0342982779397039 0.8267736724753812 1.034568226935012 1.0 17.497053562985883 -5.750901354162085 24.766303006842033 0.9570322849792308 1.0777036333625694 0.3763451036295786 0.06411789510161331 170.87323173517464 401579.2010121096 0.016382473375613393 0.027989925425814757 1.7745925168333153e-06 5.750901354162085 0.1206713483833386 S(ph)PGASNFSTLPK ddPTM_PC-9_Lapatinib_30min_R1 3 SPGASNFSTLPK 12 0 Q9Y4E8 Q9Y4E8 USP15 Ubiquitin carboxyl-terminal hydrolase 15 1 S(0.999)PGAS(0.001)NFSTLPK;S(1)PGASNFSTLPK;S(1)PGASNFSTLPK 114.21 0.00077932 65541700.0 78338.0 79338.0 73219.0 72592.0 86790.0 78401.0 64107.0 75424.0 76052.0 60034.0 True False 77220.88575457022 79154.29773551223 67199.2164535133 77930.65783981301 81685.18283570514 75047.97199165732 67426.14678203984 78928.47438884903 67486.22289693617 70410.79690972333 1.0967193831590685 1.124178410265677 0.9543879547290491 1.10679982701703 1.1601229700671785 1.065858863774536 0.9576109026075896 1.1209711841501606 0.9584641256576477 1.0 16.1035090506532 -7.014434454626085 24.565792544934315 1.0182556774295461 1.086898681537427 0.24241211501065185 0.0655284156313574 918.9457399038896 1563938.4516897057 0.02450049839024256 0.01973354684088485 9.673097056913081e-08 7.014434454626085 0.06864300410788093 S(ph)PGDFTSAAQLASTPFHK ddPTM_PC-9_AZD4547_30min_R2 1 SPGDFTSAAQLASTPFHK 18 0 O43683-2;O43683-3;O43683;A0A590UJ99 O43683-2 BUB1 Mitotic checkpoint serine/threonine-protein kinase BUB1 1 S(0.996)PGDFT(0.004)SAAQLASTPFHK 87.15700000000001 0.00094684 6216600.0 37025.0 22961.0 33864.0 50072.0 45378.0 33823.0 33468.0 41015.0 33527.0 32033.0 True False 48798.17983215829 30382.69422317256 33414.941233655474 38528.67400468832 39078.047981296055 31708.042463159443 36446.58716389301 34677.07418093774 35299.16877327294 30911.534420086387 1.5786398426229244 0.9828918167009468 1.0809861710372541 1.2464173884442404 1.2641898473957038 1.0257673408329897 1.1790610801969743 1.121816656193052 1.141941654967974 1.0 14.915857649575587 -4.750010639134148 24.999958927010507 1.1264829524887736 1.578640833761222 0.6923113100350369 0.09230529741995606 304.01346651592144 664976.5680365047 0.023263054926353208 0.35789419336721917 1.7782358471518782e-05 4.750010639134148 0.4521578812724485 S(ph)PGDFTSAAQLASTPFHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPGDFTSAAQLASTPFHK 18 0 O43683-2;O43683-3;O43683;A0A590UJ99 O43683-2 BUB1 Mitotic checkpoint serine/threonine-protein kinase BUB1 1 S(0.999)PGDFT(0.001)SAAQLASTPFHK;S(0.999)PGDFT(0.001)SAAQLASTPFHK 119.66 0.00012853 3558400.0 17285.1 16131.1 22857.1 22500.4 28757.9 27376.1 30737.0 24806.7 24598.4 22752.5 True False 20211.12603371331 17732.48900127405 23402.099950034477 21239.775535281045 23122.995935312483 25940.449123130285 27825.368843390876 24155.55040987125 24958.10506439924 26877.34814130911 0.7519761967383174 0.6597558995792491 0.8706997367075305 0.7902481831024317 0.8603153783528822 0.9651416868489768 1.0352721070954432 0.8987326533433336 0.9285925431772752 1.0 14.714103180905926 -6.025031056585226 0.8437544166876305 0.9675169859125815 0.7057305318287237 0.7296499869239623 0.057370146806206695 0.3788864403529831 0.5459651541613154 0.02857209588045164 0.06509140826138225 9.439933685003283e-07 6.025031056585226 -0.2617864540838578 S(ph)PGDFTSAAQLASTPFHK ddPTM_PC-9_Lapatinib_30min_R1 2 SPGDFTSAAQLASTPFHK 18 0 O43683-2;O43683-3;O43683;A0A590UJ99 O43683-2 BUB1 Mitotic checkpoint serine/threonine-protein kinase BUB1 1 S(0.999)PGDFT(0.001)SAAQLASTPFHK;S(0.87)PGDFT(0.071)S(0.058)AAQLASTPFHK 149.84 1.1693e-12 2016400.0 70080.0 53981.0 55463.0 56771.0 53370.0 51485.0 47791.0 43608.0 58291.0 40948.0 True False 69080.64634890186 53856.010311082755 50903.04623337129 60946.128722504334 50230.881529457096 49283.10656739686 50265.38413684106 45634.186878830835 51725.65374855763 48025.80724021966 1.4384067716627496 1.1213972946191424 1.0599102682180854 1.2690287206971593 1.045914361797354 1.0261796604664724 1.04663277985978 0.9502013500902502 1.077038715660348 1.0 15.551522243136745 -1.5228787452803376 0.6144615718280202 1.0335579778693635 26.06603894114912 0.6705850786630327 0.07895138722129368 117.53457120845489 0.8651365132744177 0.03614292177707963 3966.620919885714 0.029999999999999995 1.5228787452803376 25.032480963279756 S(ph)PGDTAKDALFASQEK ddPTM_PC-9_AZD4547_30min_R2 1 SPGDTAKDALFASQEK 16 1 Q5QNY5;P40855;E9PS71;B7Z8B3 Q5QNY5 PEX19 Peroxisomal biogenesis factor 19 1 S(0.996)PGDT(0.004)AKDALFASQEK 55.707 0.030436 4597400.0 18674.0 7786.2 20363.0 32712.0 34487.0 20017.0 13703.0 19490.0 15180.0 16852.0 True False 24611.943556670452 10302.936882560265 20092.973315052164 25170.753795361965 29699.07533895187 18765.33382565304 14922.540453771546 16478.268335644927 15982.383809415782 16262.016609349583 1.513461961570019 0.6335583790165826 1.235576976566365 1.5478248731396849 1.826284897647741 1.1539364567408088 0.9176316081974774 1.0132979649135898 0.9828045434553897 1.0 13.989218552824019 -6.998686368840861 24.997865565890685 0.9875762637514502 1.3333651253134355 0.2714883825672718 0.28747534491027477 70.90208297155321 1349204.9697077803 0.11159390763994574 0.09767592912835392 1.0030293266892947e-07 6.998686368840861 0.3457888615619853 S(ph)PGEDASPGAGHEQEAFLGVR ddPTM_PC-9_AZD4547_30min_R2 3 SPGEDASPGAGHEQEAFLGVR 21 0 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 S(0.998)PGEDAS(0.002)PGAGHEQEAFLGVR;S(0.996)PGEDAS(0.004)PGAGHEQEAFLGVR;S(0.957)PGEDAS(0.043)PGAGHEQEAFLGVR 158.11 2.0833e-06 37633800.0 12275.900000000001 11059.2 16894.03 23101.0 20671.6 19184.6 16837.0 25873.9 17804.8 19499.0 True False 16179.38084541774 14633.870125556821 16670.004123836894 17775.421356892166 17801.70515778923 17984.983929241305 18335.460382409077 21875.683278073022 18745.92537878039 18816.345945033696 0.859857747762554 0.7777211456626743 0.8859320599511353 0.9446797698563644 0.946076629851065 0.9558170317328899 0.9744432014574252 1.1625893434344936 0.9962574791907516 1.0 14.19969886952793 -6.1835527810417545 0.6294744580905448 1.0511666703817222 0.7990299304217332 0.6595816077444632 0.05608997090843776 0.5664805290790405 0.4602359044891954 0.03807567303870597 0.08129157593950401 6.553106392307101e-07 6.1835527810417545 -0.252136739959989 S(ph)PGEDASPGAGHEQEAFLGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPGEDASPGAGHEQEAFLGVR 21 0 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 S(0.631)PGEDAS(0.369)PGAGHEQEAFLGVR;S(0.95)PGEDAS(0.05)PGAGHEQEAFLGVR;S(0.953)PGEDAS(0.047)PGAGHEQEAFLGVR;S(0.777)PGEDAS(0.223)PGAGHEQEAFLGVR 156.08 7.695e-06 47704200.0 32777.5 34870.700000000004 38703.1 39090.1 42787.2 32418.9 33194.5 40412.8 44018.2 27479.899999999998 True False 38326.08336486559 38332.432643572196 39625.928686324114 36900.00842881412 34403.3553104852 30718.79581378822 30050.076652631622 39352.00682090103 44661.88290074714 32461.7883392313 1.1806522476319354 1.1808478400201383 1.220694567786171 1.136721367387485 1.0598108443984722 0.9463063307779439 0.9257061360453442 1.2122562814366773 1.3758294039140033 1.0 14.986454860552755 -6.000971061550504 4.387384544795913 1.0828474890724993 1.1920463229258675 0.12999554982867567 0.1242862534854093 0.46358831316250404 22.28340360781518 0.04022540586326235 0.05753875486993873 9.9776654602771e-07 6.000971061550504 0.10919883385336826 S(ph)PGEDASPGAGHEQEAFLGVR ddPTM_PC-9_Lapatinib_30min_R1 1 SPGEDASPGAGHEQEAFLGVR 21 0 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 S(0.959)PGEDAS(0.041)PGAGHEQEAFLGVR 137.99 6.0073999999999994e-05 7337700.0 3051.1 1556.2 3700.6 1105.8 2960.6 2958.1 3718.8 2055.4 2740.7 1535.3 True False 3007.5907544967868 1552.5967145126433 3396.3509527290958 1187.124220840662 2786.463328763553 2831.5889586678977 3911.3412677718543 2150.901387606606 2432.0135051495417 1800.6745593413411 1.670257814714124 0.8622306048909577 1.8861547941075085 0.6592663925206417 1.5474552657548502 1.5725156686301212 2.172153345245552 1.194497571173201 1.3506124649415465 1.0 10.81432174738888 S(ph)PGEPGGAAPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGEPGGAAPER 12 0 Q96EB6;Q96EB6-2 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 S(1)PGEPGGAAPER 70.563 0.029475 59388000.0 5450.3 4998.2 8915.3 7205.5 8791.9 8722.1 9639.8 5081.7 8109.5 6124.8 True False 6372.928141668125 5494.388264046962 9127.874563463527 6801.799195546186 7069.19030818223 8264.697721620481 8726.648357891776 4948.310759506217 8228.08609583329 7235.177756109879 0.8808253724362735 0.7593992088732201 1.2615964487887428 0.9401011868439972 0.9770582764483599 1.1422936657832914 1.2061415285232484 0.6839238683980536 1.137233441000801 1.0 12.820812746437461 -5.226174519593876 24.99024584903493 1.0355202048433867 0.8201122297295511 0.2433559874546879 0.1570811038847072 876.6125355799522 621204.1422009947 0.039159672828570136 0.10359682022624937 5.940533925376896e-06 5.226174519593876 -0.21540797511383558 S(ph)PGEYINIDFGEPGAR ddPTM_PC-9_AZD4547_30min_R2 4 SPGEYINIDFGEPGAR 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 S(1)PGEYINIDFGEPGAR;S(1)PGEYINIDFGEPGAR;S(1)PGEYINIDFGEPGAR;S(1)PGEYINIDFGEPGAR 165.66 2.967e-05 30410500.0 11796.599999999999 11994.2 22592.199999999997 20790.800000000003 22341.5 15349.0 16084.6 24076.200000000004 15459.2 16568.9 True False 15547.673415477073 15871.090590635267 22292.612666518744 15997.802274657972 19239.76836736142 14389.224603584384 17516.09824000101 20355.77650603665 16276.341751417693 15988.827854180656 0.9724085816216832 0.992636279243284 1.3942618476994744 1.0005612932079302 1.2033257561360715 0.8999549394624311 1.0955210975907164 1.273125002763361 1.0179821747947495 1.0 13.964776557833304 -8.495287546911502 24.888728353100145 0.9999996802027358 1.1053985253796088 0.06644308568459367 0.14312968170171925 1614.836487085798 1456669.5106632346 0.13588679012634985 0.03508581827855062 3.1967778183063216e-09 8.495287546911502 0.10539884517687304 S(ph)PGEYINIDFGEPGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPGEYINIDFGEPGAR 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 S(1)PGEYINIDFGEPGAR;S(1)PGEYINIDFGEPGAR 97.214 0.0022188000000000004 12187600.0 5757.6 7998.700000000001 7223.6 9130.3 9404.4 9114.6 10938.8 13035.8 10953.3 9981.400000000001 True False 6732.2479622164665 8792.75807443329 7395.838019655553 8618.758891831989 7561.675330050275 8636.614330663728 9902.597673946197 12693.624062571798 11113.47129089225 11790.948807281082 0.5709674490367735 0.7457209948196565 0.6272470638739874 0.7309639820087914 0.6413118616358364 0.7324783163616564 0.8398473978473385 1.076556625768174 0.9425425784250306 1.0 13.525392194939478 -7.42809687694026 2.2199202079002753 1.0077849417330522 0.6720896006902204 0.8597114529457017 0.06007891550476537 0.10137491024141677 0.9787706521520902 0.029699147818562244 0.016926464664941285 3.7316690713963115e-08 7.42809687694026 -0.33569534104283183 S(ph)PGEYINIDFGEPGAR ddPTM_PC-9_Lapatinib_30min_R1 3 SPGEYINIDFGEPGAR 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 S(1)PGEYINIDFGEPGAR;S(0.999)PGEY(0.001)INIDFGEPGAR;S(1)PGEYINIDFGEPGAR 149.69 2.012e-05 14492200.0 14339.6 15700.199999999999 14417.099999999999 14201.500000000002 19517.3 18557.8 18505.5 17770.3 22645.5 15963.3 True False 14135.114674439423 15663.847151517415 13231.78168961538 15245.925684815214 18369.330786488175 17764.12615434472 19463.624241893078 18595.973011669586 20094.92532231327 18722.535135239796 0.7549786699470057 0.8366306719881498 0.7067302367995214 0.8143088302245531 0.981134801126007 0.948809871421144 1.039582732856428 0.9932401182502261 1.0733015148408158 1.0 14.1924881766187 -6.259011244940449 2.6461914299491345 1.0101755859158061 0.7698880163929773 0.8767893264656104 0.04222494154158979 0.0923945541568971 1.2860349897673993 0.013643369637567338 0.01723844000828998 5.507934348390754e-07 6.259011244940449 -0.24028756952282881 S(ph)PGFASPK ddPTM_PC-9_AZD4547_30min_R2 2 SPGFASPK 8 0 P49790-3;P49790 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 S(1)PGFASPK;S(1)PGFASPK 83.499 0.014968 25450000.0 113009.0 140673.0 127546.0 87554.0 97901.0 125567.0 105336.0 136654.0 115085.0 95098.0 True False 148943.51126677557 186142.7962395519 125854.65670292408 67369.77799581563 84309.13604426972 117715.27563999491 114710.6999371289 115537.26429652242 121168.15814931596 91768.64796557852 1.6230326431598159 2.02839205290866 1.37143413892434 0.7341263000963613 0.9187139389467001 1.2827395657408913 1.2499988011173022 1.2590058463088534 1.320365515189511 1.0 16.485713731988298 -5.464892433380038 5.4222258886029335 1.1195814372645565 1.8098772868853266 0.6726207667832204 0.197874343254636 0.12668677306126486 7.819853606996784 0.05623768737387313 0.11735750389368196 3.4285269423051004e-06 5.464892433380038 0.6902958496207701 S(ph)PGFASPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGFASPK 8 0 P49790-3;P49790 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 S(1)PGFASPK 77.37899999999999 0.023625 5040300.0 23653.0 30723.0 29486.0 31176.0 48140.0 44467.0 70505.0 39988.0 47910.0 47602.0 True False 27656.985731955327 33772.97639876652 30189.058066277707 29429.309793955716 38707.31257588152 42135.072240320354 63826.255988003824 38938.357370788246 48610.593113184856 56231.86578277535 0.4918383081720022 0.6006020950688725 0.5368674442156792 0.5233564525075807 0.6883519164277516 0.7493095179002036 1.135054921253471 0.6924607040642717 0.8644670141476081 1.0 15.77910029608672 -6.713952975930493 2.0876513807213 0.8985152764321734 0.5454047667973364 0.6895149668854927 0.11310202608198203 0.18952804096480802 1.6980918293822787 0.04356536679770745 0.04137299970720429 1.9321775159241498e-07 6.713952975930493 -0.35311050963483703 S(ph)PGFASPK ddPTM_PC-9_Lapatinib_30min_R1 2 SPGFASPK 8 0 P49790-3;P49790 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 S(1)PGFASPK;S(1)PGFASPK 104.42 0.0038583 20608000.0 45097.0 58128.0 53837.0 47701.0 108545.0 145782.0 184380.0 160414.0 139094.0 140313.0 True False 44453.90851022306 57993.40818737369 49410.72967682978 51209.09066587124 102160.59650768069 139547.24369444003 193926.29422173108 167867.42006009835 123427.76899524589 164565.91509467948 0.27012828558482144 0.35240230733082495 0.3002488677464126 0.3111767745854856 0.620788311169447 0.8479717298333285 1.1784110586336163 1.0200619002028422 0.7500202513031593 1.0 17.328306030026255 -6.591616437256338 1.995438838503049 0.9896112754362878 0.30668537049649086 0.8997175709385473 0.10292742030398062 0.0972937180696094 0.7884640957936917 0.04041399532983735 0.04172212940586467 2.560846591936174e-07 6.591616437256338 -0.6829259049397969 down S(ph)PGGGSEANGLALVSGFK ddPTM_PC-9_AZD4547_30min_R2 3 SPGGGSEANGLALVSGFK 18 0 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 S(1)PGGGSEANGLALVSGFK;S(1)PGGGSEANGLALVSGFK;S(1)PGGGSEANGLALVSGFK 233.34 3.6e-43 80197700.0 47192.0 49961.0 55827.0 75106.0 68504.0 60547.0 55253.0 69957.0 54486.0 60907.0 True False 62198.07434542101 66109.91620939532 55086.69750328623 57791.47207613276 58993.402065113165 56760.98651854994 60170.409960755984 59146.7531019349 57366.018724626396 58774.664468647985 1.0582463533858055 1.1248029539098459 0.9372524369351523 0.9832718331715924 1.003721630713551 0.9657390141091796 1.0237474004271436 1.006330765758525 0.9760331129619124 1.0 15.842906777429459 -5.255417123394336 24.999273196153375 0.9882535434753962 1.0915246578086408 0.7006679776126068 0.027314665671331197 252.12383852128065 1046595.6825619926 0.006863270395706728 0.017188598601444702 5.553705886199378e-06 5.255417123394336 0.10327111433324465 S(ph)PGGGSEANGLALVSGFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPGGGSEANGLALVSGFK 18 0 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 S(1)PGGGSEANGLALVSGFK;S(0.993)PGGGS(0.007)EANGLALVSGFK;S(0.999)PGGGS(0.001)EANGLALVSGFK;S(0.991)PGGGS(0.009)EANGLALVSGFK 198.88 9.3037e-15 93527000.0 86523.0 82743.0 92454.0 108649.0 129719.0 91213.0 102412.0 86545.0 79653.0 86825.0 True False 101169.63499285371 90957.17821056323 94658.45399374774 102561.74877481042 104301.49314563279 86429.62970869041 92710.7939613283 84273.28545200714 80817.77443632895 102565.68519367801 0.9863887205726934 0.8868188033727452 0.9229056854151678 0.999961620508261 1.0169238663854971 0.8426758866328696 0.9039162931175235 0.8216518545444438 0.7879611420107827 1.0 16.646188611995612 -6.776491642621536 24.98710219460443 0.8621364625288975 0.9582601272826503 0.33397694785160803 0.06371584238381608 275.75177387912663 457751.4208735098 0.02251151267189908 0.019930769668260327 1.6730478315104086e-07 6.776491642621536 0.09612366475375278 S(ph)PGGGSEANGLALVSGFK ddPTM_PC-9_Lapatinib_30min_R1 4 SPGGGSEANGLALVSGFK 18 0 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 S(1)PGGGSEANGLALVSGFK;S(1)PGGGSEANGLALVSGFK;S(0.999)PGGGS(0.001)EANGLALVSGFK;S(0.998)PGGGS(0.002)EANGLALVSGFK 214.52 2.0821e-27 72179400.0 122623.0 108675.0 110560.0 96187.0 111266.0 110911.0 99107.0 105628.0 107509.0 85049.0 True False 120874.37353369569 108423.3697144723 101470.18357394187 103260.91285042584 104721.5526373727 106167.59507616881 104238.27552572456 110535.86249397225 95400.20430004084 99749.6063293308 1.211777950627894 1.0869553645806322 1.0172489627571106 1.0352012068047889 1.0498442699776342 1.0643409932431067 1.0449993675320792 1.1081333206371744 0.956396800054227 1.0 16.606023527171722 -4.800421861567955 2.8442868875781606 1.040573282513108 1.2385181445762308 0.6605792691315626 0.03826575299059874 0.233244211961452 2.7140048723450487 0.009323341021406643 0.10664328440454761 1.583354418822989e-05 4.800421861567955 0.19794486206312278 S(ph)PGGGSEANGLALVSGFKR ddPTM_PC-9_AZD4547_30min_R2 2 SPGGGSEANGLALVSGFKR 19 1 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 S(0.994)PGGGS(0.006)EANGLALVSGFKR;S(0.818)PGGGS(0.182)EANGLALVSGFKR 84.948 0.00060692 17991000.0 27464.0 24125.6 38181.0 58818.0 57188.0 37820.0 35290.0 39726.0 32473.0 41490.0 True False 36196.98071331248 31923.72839817831 37674.694992977784 45258.41882904131 49248.433336734946 35455.10942130178 38430.74163421133 33587.259512664445 34189.45648505657 40037.447728573134 0.9040781260260037 0.7973467393476137 0.9409864297141711 1.130402195860806 1.2300592602856726 0.8855486908572066 0.9598699171522074 0.838896118962512 0.8539369621369975 1.0 15.289062389020778 -10.381031376936571 10.012838066734105 0.9999999884658154 0.9531318433296988 0.013284734848226454 0.12745142538936577 0.0 0.0 0.13745854068161897 0.03333859283240679 4.1588056284206907e-11 10.381031376936571 -0.04686814513611659 S(ph)PGGGSEANGLALVSGFKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGGGSEANGLALVSGFKR 19 1 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 S(0.99)PGGGS(0.01)EANGLALVSGFKR 77.795 0.0015134 5357400.0 23029.0 12208.0 18804.0 21500.0 24170.0 33095.0 28678.0 22225.0 28662.0 28293.0 True False 26927.354856517115 13419.929560138717 19252.358674567116 20295.42470394047 19434.062005796764 31359.439939582222 25961.41222925997 21641.617299334004 29081.127526823315 33422.29693273522 0.8056703855725523 0.4015262501900241 0.576033380150798 0.6072420679161122 0.5814699703287664 0.938279017827391 0.776769241249612 0.6475203467580136 0.8701115780687121 1.0 15.028523264941217 -6.742676129977246 24.870439017211822 0.8201456178410902 0.5833681245219561 0.48628304461788163 0.12790341861715182 208.45867500143464 276308.61042415473 0.04122255551064647 0.04115307158114752 1.808522307579821e-07 6.742676129977246 -0.2367774933191341 S(ph)PGGPGSHVR ddPTM_PC-9_AZD4547_30min_R2 1 SPGGPGSHVR 10 0 O75382-3;O75382-2;O75382;A0A1W2PPI7;O75382-4 O75382-3 TRIM3 Tripartite motif-containing protein 3 1 S(1)PGGPGSHVR 68.46300000000001 0.023191999999999997 1945300.0 6652.7 5723.7 9670.1 15119.0 7788.9 11470.0 9189.8 10755.0 11327.0 9434.9 True False 8768.120215243736 7573.774091946036 9541.868155668903 11633.54813622149 6707.54568120051 10752.77908678825 10007.674396998447 9093.061875313555 11925.722095471185 9104.587022760054 0.9630442537728288 0.8318635510883444 1.0480286620157195 1.2777678006854596 0.7367215739091392 1.18102875615423 1.0991903720597997 0.9987341383614998 1.3098586531886325 1.0 13.152377863783103 -5.374929848808574 5.931166387915027 1.0820149688490366 0.8992610905714661 0.1850178223129777 0.15561197843746047 0.356197659600046 16.032832766347216 0.03944543068671212 0.08361399434430737 4.21764625181713e-06 5.374929848808574 -0.1827538782775705 S(ph)PGGPGSHVR ddPTM_PC-9_Lapatinib_30min_R1 2 SPGGPGSHVR 10 0 O75382-3;O75382-2;O75382;A0A1W2PPI7;O75382-4 O75382-3 TRIM3 Tripartite motif-containing protein 3 1 S(1)PGGPGSHVR;S(1)PGGPGSHVR 92.792 0.004084 3284470.0 11105.9 10214.5 13538.2 12256.5 9832.4 8936.199999999999 8883.8 9251.7 10713.0 7518.0 True False 10947.52782942738 10190.848952827004 12425.141454963272 13157.883896485419 9254.07756324216 8554.019557299638 9343.759695232753 9681.567756991355 9506.389127108787 8817.476282894682 1.2415715651727757 1.1557557543530423 1.4091494046961284 1.4922505572269968 1.0495154470893735 0.9701210735200805 1.059686399538043 1.0979975954994008 1.0781303881191662 1.0 13.10615007478101 -6.29070144791082 23.07858133185921 1.0447077634200108 1.3186490308219203 0.6979891862870551 0.09086763986525369 171.67075213768632 135393.59427336347 0.03096856694871287 0.0351240930198072 5.12033707846892e-07 6.29070144791082 0.2739412674019095 S(ph)PGHMVILDQTK ddPTM_PC-9_AZD4547_30min_R2 6 SPGHMVILDQTK 12 0 Q9NWH9;Q9NWH9-3;H7C3F4 Q9NWH9 SLTM SAFB-like transcription modulator 1 S(1)PGHMVILDQTK;S(1)PGHMVILDQTK;S(1)PGHMVILDQTK;S(1)PGHMVILDQTK;S(1)PGHMVILDQTK;S(1)PGHMVILDQTK 178.68 0.00016071 203421100.0 540799.8 634671.0 680049.0 692071.0 657708.0 776303.0 637930.0 797330.0 672916.0 636806.0 True False 712762.8870653661 839815.9890821467 671031.1059238763 532524.7233403632 566396.5970664709 727760.6506897097 694704.5341658369 674120.9693206648 708484.965974759 614511.6157686615 1.1598851328038886 1.3666397306935578 1.0919746489812359 0.8665820298193306 0.9217020191847701 1.1842911216241059 1.1304986209200718 1.097002810072908 1.152923635281574 1.0 19.22908075574827 -5.406224711253509 6.447825748508183 1.052392349585263 1.2607362505150128 0.38654532661753327 0.10560163749634864 0.2505180285096424 12.311497653534481 0.030015637293329435 0.0631455914560159 3.9244182687084955e-06 5.406224711253509 0.20834390092974986 S(ph)PGHMVILDQTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SPGHMVILDQTK 12 0 Q9NWH9;Q9NWH9-3;H7C3F4 Q9NWH9 SLTM SAFB-like transcription modulator 1 S(1)PGHMVILDQTK;S(1)PGHMVILDQTK;S(1)PGHMVILDQTK;S(1)PGHMVILDQTK;S(0.999)PGHMVILDQT(0.001)K 117.95 0.00042109 231330000.0 576314.0 741429.0 728073.0 685902.0 800133.0 582854.0 642929.0 571756.0 579268.0 549840.0 True False 673872.5774796472 815033.1711864413 745433.0215522292 647473.1346642858 643352.6824527989 552288.1101841743 582026.1107171299 556748.0108255568 587738.6986326101 649521.6394689553 1.03749057233967 1.2548206582505967 1.1476646446478524 0.9968461330921256 0.9905023071730141 0.8502997846780308 0.8960842493146043 0.8571662235622363 0.9048793187447018 1.0 19.309018065751992 -6.042544949595903 1.645295942586677 0.8971754604936818 1.161350040384484 0.6985996023006915 0.06734803062068395 0.1852963359617727 1.007297847879422 0.022176736627719046 0.03595486037779957 9.066821178838922e-07 6.042544949595903 0.2641745798908023 S(ph)PGHMVILDQTK ddPTM_PC-9_Lapatinib_30min_R1 12 SPGHMVILDQTK 12 0 Q9NWH9;Q9NWH9-3;H7C3F4 Q9NWH9 SLTM SAFB-like transcription modulator 1 S(1)PGHMVILDQTK;S(1)PGHMVILDQTK;S(1)PGHMVILDQTK;S(1)PGHMVILDQTK;S(1)PGHMVILDQTK;S(1)PGHMVILDQTK;S(1)PGHMVILDQTK;S(1)PGHMVILDQTK;S(1)PGHMVILDQTK;S(1)PGHMVILDQTK;S(1)PGHMVILDQTK;S(1)PGHMVILDQTK 215.09 5.2585e-11 104775700.0 430240.0 547235.0 545659.0 431396.0 546983.0 557146.0 531673.0 530588.0 530251.0 453784.0 True False 424104.69870364625 545967.9109795187 500797.0233246529 463122.3009348687 514810.5353499538 533318.16435076 559200.4264440308 555241.0554867246 470528.5485894296 532219.9597708274 0.7968598150401286 1.0258313333731621 0.940958741081967 0.8701708615631176 0.9672890426199534 1.0020634411764744 1.0506942029848356 1.0432548522340461 0.8840866261236012 1.0 19.021663091002168 -6.507298665160446 5.038761246639042 1.0009384229427896 0.9187027298835893 0.2599330598372037 0.06865328790854056 0.27692059482079184 20.16178564505107 0.022084854853151023 0.023726917035892404 3.109577139374372e-07 6.507298665160446 -0.08223569305920031 S(ph)PGKAEAESDALPDDTVIESEALPSDIAAEAR ddPTM_PC-9_AZD4547_30min_R2 4 SPGKAEAESDALPDDTVIESEALPSDIAAEAR 32 1 G3V529;Q9GZR7-2;Q9GZR7;A0A1W2PRR2;F5GYL3 G3V529 DDX24 ATP-dependent RNA helicase DDX24 1 S(0.5)PGKAEAES(0.5)DALPDDTVIESEALPSDIAAEAR;S(0.981)PGKAEAES(0.019)DALPDDTVIESEALPSDIAAEAR;S(0.902)PGKAEAES(0.096)DALPDDT(0.001)VIESEALPSDIAAEAR;S(0.973)PGKAEAES(0.027)DALPDDTVIESEALPSDIAAEAR 96.913 3.9648000000000004e-13 27655700.0 74556.26 80301.0 84593.6 94914.2 80585.0 78438.7 66693.2 75627.09999999999 71644.79999999999 88853.3 True False 98263.59981345426 106256.72787835814 83471.83359152373 73033.19759977199 69397.16374835257 73533.91568917685 72628.76559815185 63940.66943287073 75431.79786224183 85742.57301183973 1.1460304532718602 1.2392528489165553 0.9735167800480812 0.8517728712163469 0.8093664711784412 0.8576126550228781 0.8470560545007546 0.7457283725791796 0.8797473088640092 1.0 16.387724090566287 -5.46406745693388 2.9019661242112256 0.8434907121567478 1.1935779288870276 0.8038811175500011 0.0654048139852745 0.09686520014908438 1.592133100004049 0.0172027148554838 0.03987699331395773 3.4350458879223315e-06 5.46406745693388 0.35008721673027987 S(ph)PGKAEAESDALPDDTVIESEALPSDIAAEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPGKAEAESDALPDDTVIESEALPSDIAAEAR 32 1 G3V529;Q9GZR7-2;Q9GZR7;A0A1W2PRR2;F5GYL3 G3V529 DDX24 ATP-dependent RNA helicase DDX24 1 S(0.962)PGKAEAES(0.038)DALPDDTVIESEALPSDIAAEAR;S(0.93)PGKAEAES(0.065)DALPDDT(0.004)VIESEALPSDIAAEAR;S(0.955)PGKAEAES(0.045)DALPDDTVIESEALPSDIAAEAR 94.57 5.315300000000001e-13 26724500.0 48499.1 39265.3 34842.9 55920.0 52477.4 47990.2 49635.6 54125.0 46371.0 36209.8 True False 56709.039729111544 43163.29948867257 35673.6868784341 52786.98369508612 42194.83018216795 45473.50943008121 44933.75663737557 52704.27610017785 47049.0881496868 42774.350103380915 1.3257720945391809 1.0090930518956245 0.8339971686820421 1.2340803207414202 0.9864516954714139 1.0631022872393554 1.050483678390802 1.2321467415120835 1.0999369490354456 1.0 15.384458314690738 S(ph)PGKAEAESDALPDDTVIESEALPSDIAAEAR ddPTM_PC-9_Lapatinib_30min_R1 5 SPGKAEAESDALPDDTVIESEALPSDIAAEAR 32 1 G3V529;Q9GZR7-2;Q9GZR7;A0A1W2PRR2;F5GYL3 G3V529 DDX24 ATP-dependent RNA helicase DDX24 1 S(0.98)PGKAEAES(0.019)DALPDDT(0.001)VIESEALPSDIAAEAR;S(0.972)PGKAEAES(0.028)DALPDDTVIESEALPSDIAAEAR;S(0.792)PGKAEAES(0.208)DALPDDTVIESEALPSDIAAEAR;S(0.897)PGKAEAES(0.103)DALPDDTVIESEALPSDIAAEAR;S(0.909)PGKAEAES(0.091)DALPDDTVIESEALPSDIAAEAR 94.929 5.1084e-13 24555800.0 79748.19999999998 63968.9 70127.5 60369.50000000001 62289.9 59570.399999999994 62508.4 63902.700000000004 58947.6 50919.0 True False 78610.97604397127 63820.78394228752 64361.88764997837 64809.274416748434 58626.130548655274 57022.712857384846 65744.77909604984 66871.8527302758 52308.300542253106 59720.28130469734 1.3163195873591451 1.0686618104939778 1.0777224461083699 1.0852138168286025 0.9816787407537546 0.9548299440595516 1.100878590316999 1.1197511342769906 0.8758883816265407 1.0 15.865933340667182 -1.741457546721848 1.0209387652828061 1.0226110479606043 199.99999973270425 0.6041875443093452 0.07079434718748466 803.8298792115759 1.6244396504632177 0.021766738019893754 373499.85455219756 0.018136039511372035 1.741457546721848 198.97738868474366 S(ph)PGKCDQEKPAPSFACLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGKCDQEKPAPSFACLK 18 2 Q01850;H3BUE0;H3BTR1;H3BU23 Q01850 CDR2 Cerebellar degeneration-related protein 2 1 S(1)PGKCDQEKPAPSFACLK 53.059 0.016242 5516100.0 17757.0 16510.0 14242.0 20110.0 23019.0 23572.0 23253.0 23915.0 22769.0 14169.0 True False 20762.909383263464 18149.003689211182 14581.583293085772 18983.30189749966 18508.592193274137 22335.84282386559 21050.307502858697 23287.25659003702 23101.953550283997 16737.72753825772 1.2404855638739078 1.0843170703865075 0.871180586477847 1.1341624395611165 1.1058007815558426 1.3344608921857617 1.2576562412516057 1.3913033616307187 1.3802323820530267 1.0 14.03081604771052 -6.690007275335425 5.074289340933223 1.2961917081008847 1.0741395863455436 0.31572723814987025 0.13410478183950258 0.21879156748863157 10.403605033524059 0.04477607221993157 0.044171557247500486 2.0417037416008813e-07 6.690007275335425 -0.22205212175534106 S(ph)PGKCDQEKPAPSFACLK ddPTM_PC-9_Lapatinib_30min_R1 2 SPGKCDQEKPAPSFACLK 18 2 Q01850;H3BUE0;H3BTR1;H3BU23 Q01850 CDR2 Cerebellar degeneration-related protein 2 1 S(1)PGKCDQEKPAPSFACLK;S(0.999)PGKCDQEKPAPS(0.001)FACLK 52.861999999999995 0.016678 22488000.0 150742.0 126012.0 122783.0 126423.0 118559.0 128916.0 88849.0 93589.0 111618.0 93671.0 True False 148592.39143730298 125720.22695615394 112688.25569608627 135720.56915476496 111585.59271596225 123402.5631978737 93449.16647850422 97937.48660344198 99046.40545035263 109861.90754123796 1.352537879260171 1.1443477522813208 1.0257263706602529 1.2353742274484052 1.0156895616806698 1.1232515979349174 0.8506057155745905 0.8914599135890663 0.9015536655703379 1.0 16.745331721254686 -6.7899560861949535 1.009358210842331 0.8999060583806457 1.1870446284758491 0.5843029500270911 0.09803346201700401 0.379434649561502 0.8266696419263241 0.05651169700991422 0.04995042215872273 1.6219740954206933e-07 6.7899560861949535 0.2871385700952034 S(ph)PGLCSDSLEK ddPTM_PC-9_AZD4547_30min_R2 2 SPGLCSDSLEK 11 0 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 S(1)PGLCSDSLEK;S(1)PGLCSDSLEK 132.14 0.00012319999999999999 67922000.0 96994.0 112390.0 123474.0 152293.0 144785.0 163161.0 128468.0 152021.0 152280.0 137079.0 True False 127836.0743994696 148717.8695937617 121836.65408352173 117184.20175339497 124684.10192101811 152958.51687702307 139901.40312450737 128529.64754505262 160329.20991421858 132279.9059336001 0.9664058459766282 1.1242665206340023 0.9210518651614364 0.8858805948366592 0.9425777939667207 1.1563246571539212 1.0576164394517562 0.9716490697352781 1.2120450856284875 1.0 17.013234399154854 -6.742524936399376 24.969352425746315 1.076385723804298 0.9695414749785282 0.28987743234659324 0.08716515900698055 345.22932056094623 455743.68142857763 0.02944819811313455 0.029402701936728247 1.8091520290519917e-07 6.742524936399376 -0.10684424882576982 S(ph)PGLCSDSLEK ddPTM_PC-9_Lapatinib_30min_R1 2 SPGLCSDSLEK 11 0 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 S(1)PGLCSDSLEK;S(1)PGLCSDSLEK 179.67 0.0012158 76645000.0 137738.0 197757.0 199237.0 200783.0 230120.0 222130.0 215200.0 210078.0 218510.0 168364.0 True False 135773.83086194456 197299.1058166543 182856.50293706093 215549.25161245328 216584.79403332734 212630.0177103208 226342.0030183133 219838.99080744435 193899.10278769143 197465.49306907173 0.6875825682335903 0.999157385678726 0.926017503590358 1.0915793350135155 1.096823504031501 1.076795820908034 1.1462357270651882 1.113303329055809 0.9819391721259734 1.0 17.591241039991665 -4.226305510566211 0.9872674551682228 1.0775233796969519 6.351244346330186e-12 0.7523737817906456 0.06291707067105108 2.3996984274327953 0.8735433284809838 0.01997441628785214 3.5750923377481763 5.9387424244337115e-05 4.226305510566211 -1.0775233796906007 S(ph)PGLLDTTPIR ddPTM_PC-9_AZD4547_30min_R2 3 SPGLLDTTPIR 11 0 Q8IY92;Q8IY92-2 Q8IY92 SLX4 Structure-specific endonuclease subunit SLX4 1 S(1)PGLLDTTPIR;S(1)PGLLDTTPIR;S(1)PGLLDTTPIR 116.54 0.0012509 17986800.0 20151.8 24131.7 28826.9 31429.3 27357.5 30186.2 28527.7 32238.7 25485.5 28161.5 True False 26559.653216520914 31931.800103886293 28444.63647083816 24183.7604628445 23559.383349823853 28298.65214207561 31066.610034522262 27256.949686626784 26832.61150032055 27175.574456693495 0.9773354840702961 1.1750184031904176 1.0466986269661758 0.8899079760533969 0.8669323030270312 1.0413267321053996 1.1431813551551395 1.0029944253823582 0.9873797348085691 1.0 14.730022911842083 -5.529213957907875 24.980299203173864 0.9917772657426973 1.0848473505278975 0.15003122722047046 0.0844063749250435 278.5306576598315 1098266.87191992 0.02481045765985453 0.0431047497422585 2.9565555420173473e-06 5.529213957907875 0.09307008478520018 S(ph)PGLLDTTPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPGLLDTTPIR 11 0 Q8IY92;Q8IY92-2 Q8IY92 SLX4 Structure-specific endonuclease subunit SLX4 1 S(0.962)PGLLDT(0.002)T(0.037)PIR;S(1)PGLLDTTPIR 111.94 0.0017500999999999997 12301300.0 11487.400000000001 12599.8 15221.900000000001 11771.4 14529.5 9043.699999999999 10166.9 12804.2 8930.6 7784.200000000001 True False 13431.98993350796 13850.624874822719 15584.847825377221 11111.886621393718 11682.548775888457 8569.432451476041 9203.817630018237 12468.103317171317 9061.193129964702 9195.413840306705 1.4607270718617216 1.506253564587882 1.694850073746915 1.2084161533531472 1.2704755847615876 0.9319246094083586 1.000913910984049 1.3559045339013753 0.9854035160708411 1.0 13.166698789361613 -5.996958972226634 2.442776192702749 1.0931586222987897 1.5472705822172241 0.6741910477244615 0.14170597626706746 0.17438587495031815 2.092270300261023 0.04404819548824634 0.06736236357645432 1.0070267981188496e-06 5.996958972226634 0.45411195991843445 S(ph)PGLVPPSPEFAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGLVPPSPEFAPR 14 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 S(0.511)PGLVPPS(0.489)PEFAPR 84.81700000000001 0.007137699999999999 9279200.0 22175.0 29832.0 24091.0 21240.0 20866.0 20071.0 22857.0 20255.0 20089.0 13716.0 True False 25928.78952378597 32793.52380718037 24665.420805626283 20049.991661009102 16777.45708783431 19018.441427023856 20691.819489650443 19723.327711946476 20382.76362034589 16202.602224203732 1.6002855075373688 2.023966481025673 1.522312309116658 1.2374550324427562 1.0354791690665497 1.1737893187684243 1.2770676711880662 1.2172938296592521 1.257993212343247 1.0 13.983937915774431 -5.602800843742345 3.003528461144036 1.1767062045049463 1.8116788435994642 0.8008567512960137 0.12939214500137244 0.09843664995572507 1.7787311714983942 0.03505175358341877 0.06951246539958436 2.495738946133824e-06 5.602800843742345 0.6349726390945178 S(ph)PGLYFLTAGDQGTLR ddPTM_PC-9_AZD4547_30min_R2 1 SPGLYFLTAGDQGTLR 16 0 A0A087WYP7;J3KNP2;Q12788 A0A087WYP7 TBL3 Transducin beta-like protein 3 1 S(0.999)PGLY(0.001)FLTAGDQGTLR 112.12 0.00038233 1746500.0 933.82 2989.9 4327.2 6722.5 6351.2 3641.5 3816.2 5575.1 2298.8 3617.2 True False 1230.7553353373676 3956.3267043187884 4269.818500657745 5172.73148658965 5469.445509692087 3413.7964293408386 4155.834407041012 4713.596398053053 2420.309874906787 3490.5629289899916 0.3525950857713061 1.1334351463657948 1.2232463896284014 1.4819189889484101 1.5669236226245873 0.9780074156487516 1.190591458049868 1.3503828734630352 0.6933866898102632 1.0 11.769244005730691 -4.75918056547709 4.1849729520008365 1.2134206516506725 0.26404769851670906 0.5100345422983514 0.2424613233761045 0.18952762245281946 6.559559766537951 0.06120964737677802 0.5579366205284598 1.7410828374443084e-05 4.75918056547709 -0.9493729531339634 S(ph)PGLYFLTAGDQGTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPGLYFLTAGDQGTLR 16 0 A0A087WYP7;J3KNP2;Q12788 A0A087WYP7 TBL3 Transducin beta-like protein 3 1 S(1)PGLYFLTAGDQGTLR;S(1)PGLYFLTAGDQGTLR 104.94 0.0011876 3644700.0 4533.3 5247.8 4452.45 6988.33 5654.4 6246.63 5082.6 6079.219999999999 5743.969999999999 4617.4 True False 5300.698153243694 5768.766902498028 4558.613294010653 6596.79652657155 4546.460910450029 5919.045726236362 4601.139333162588 5919.646916466019 5827.964694726375 5454.4980686817125 0.9718031038784124 1.057616453403983 0.8357530310964828 1.2094232032913557 0.8335250747552019 1.0851678104392335 0.8435495393391217 1.0852780296055229 1.0684694762638214 1.0 12.413230728297918 S(ph)PGLYFLTAGDQGTLR ddPTM_PC-9_Lapatinib_30min_R1 2 SPGLYFLTAGDQGTLR 16 0 A0A087WYP7;J3KNP2;Q12788 A0A087WYP7 TBL3 Transducin beta-like protein 3 1 S(1)PGLYFLTAGDQGTLR;S(0.999)PGLY(0.001)FLTAGDQGTLR 151.73 1.8099000000000001e-10 0.0 4420.1 3806.8999999999996 3296.6000000000004 3004.5 4846.799999999999 4687.6 1402.33 4586.5 3759.8 2389.85 True False 4357.068563452932 3798.0853569452374 3025.5662732440005 3225.460952718185 4561.72075317543 4487.12227532931 1474.9357857466118 4799.605533841444 3336.3317315507898 2802.932388225042 1.5544679499786462 1.3550399477706905 1.0794289173560627 1.1507451861015847 1.6274815519414443 1.6008671112365938 0.526211688852265 1.7123515194316894 1.1903004673129212 1.0 11.452721229050729 -14.057076018259988 0.17752356470376088 4.034783037416106e-08 1.3731646609028978 0.0829116033569145 0.33217637662506266 338.45860548295025 3.75669430931275 121.16827905352922 1.0912632137281975 8.768473256588685e-15 14.057076018259988 1.3731646205550674 S(ph)PGMLEPLGSSR ddPTM_PC-9_AZD4547_30min_R2 5 SPGMLEPLGSSR 12 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(1)PGMLEPLGSSR;S(1)PGMLEPLGSSR;S(1)PGMLEPLGSSR;S(1)PGMLEPLGSSR;S(1)PGMLEPLGSSR 104.94 0.0018509 153976800.0 248932.0 247967.7 350914.3 397567.9 389843.2 373146.2 365861.3 444758.6 319498.89999999997 314179.89999999997 True False 328087.1978927432 328118.40975233604 346260.94709866965 305914.763017825 335720.2008634576 349813.30912593694 398422.246932748 376031.377905889 336386.9595840679 303180.55732991826 1.082151180082837 1.0822541281737952 1.142094830051624 1.0090184070904369 1.1073276064273805 1.1538118150012944 1.3141418118681951 1.240288563414359 1.1095268197492452 1.0 18.209817712302367 -6.796560068080703 3.600495550350942 1.1909017471544152 1.0819507088347853 0.15721238629066825 0.08387406796516654 0.3173422278808713 8.587794348789357 0.02986948601408364 0.027243951115952163 1.597496561045552e-07 6.796560068080703 -0.10895103831962993 S(ph)PGMLEPLGSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SPGMLEPLGSSR 12 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(1)PGMLEPLGSSR;S(1)PGMLEPLGSSR;S(1)PGMLEPLGSSR;S(1)PGMLEPLGSSR;S(1)PGMLEPLGSSR 108.32 0.0014456 140594600.0 129791.9 191829.5 198808.9 181964.9 223907.5 178845.90000000002 208391.9 149540.1 154426.6 116496.59999999999 True False 151763.10516312378 210873.06500300084 203549.25816295165 171769.99659116584 180034.43270843787 169466.90616378683 188651.5106052976 145614.83082583276 156684.79687857546 137616.51139342212 1.102797212532579 1.5323238677381579 1.4791049133707441 1.248178687658378 1.3082327904225834 1.2314431200723428 1.3708493893292726 1.0581203472710103 1.1385610294293858 1.0 17.07029405113613 -7.899053251760777 0.7055094233927826 0.9986186741531454 1.3597071256497881 0.4447049716427436 0.12554741959878962 0.5933230446134615 0.5944530018605583 0.11743334864928888 0.05479909490749858 1.2616728229344203e-08 7.899053251760777 0.3610884514966427 S(ph)PGMLEPLGSSR ddPTM_PC-9_Lapatinib_30min_R1 7 SPGMLEPLGSSR 12 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(1)PGMLEPLGSSR;S(1)PGMLEPLGSSR;S(1)PGMLEPLGSSR;S(1)PGMLEPLGSSR;S(1)PGMLEPLGSSR;S(1)PGMLEPLGSSR;S(1)PGMLEPLGSSR 151.66 8.8311e-05 226760000.0 323518.39999999997 384094.5 422607.7 322825.7 420718.1 389384.0 389557.9 344247.2 397923.9 314822.8 True False 318904.96828999167 383205.1527839462 387862.5262188969 346567.37889296556 395972.28852160904 372730.9540184374 409727.3019405563 360242.1816481891 353105.5200575675 369239.5015049871 0.863680529819165 1.0378227443760386 1.050436165789424 0.9385977867492182 1.0723995859263742 1.0094557935952666 1.109651866256304 0.975632835002415 0.956304833633295 1.0 18.49419737622034 -4.757200307969421 24.99765926707319 1.01897121952601 0.8636803013195871 0.4554697641308114 0.050138436893664776 115.3999496457141 680420.5098503159 0.012353849357223666 0.09366654397195093 1.7490397996766217e-05 4.757200307969421 -0.15529091820642305 S(ph)PGNLTEREELAGSLAR ddPTM_PC-9_Lapatinib_30min_R1 1 SPGNLTEREELAGSLAR 17 1 Q9H0F6;Q9H0F6-2 Q9H0F6 SHARPIN Sharpin 1 S(0.846)PGNLT(0.154)EREELAGSLAR 64.58800000000001 0.01068 14362000.0 1798.5 4165.7 5627.9 3828.4 3896.0 4224.2 4386.0 4423.2 4060.7 3417.4 True False 1772.853060195493 4156.0545775898445 5165.195786322242 4109.953307168017 3666.844939830708 4043.540813091147 4613.085619137179 4628.718019685481 3603.3412049333187 4008.0930366007306 0.4423183404193263 1.0369156952291207 1.28869158953028 1.0254136492434502 0.914860235614831 1.0088440503168759 1.1509427493353654 1.154842958338887 0.8990163581605175 1.0 11.968700281689388 -4.7630851112621855 6.238489459614032 1.0632824825174039 0.42272114837319963 0.7297376116180996 0.11150334021325017 0.06545113204475185 10.83252985247019 0.028696025062425825 0.17910893421302135 1.7254997024550015e-05 4.7630851112621855 -0.6405613341442042 S(ph)PGNTSQPPAFFSK ddPTM_PC-9_AZD4547_30min_R2 4 SPGNTSQPPAFFSK 14 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2;H7C184 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 S(1)PGNTSQPPAFFSK;S(1)PGNTSQPPAFFSK;S(1)PGNTSQPPAFFSK;S(0.933)PGNT(0.059)S(0.006)QPPAFFS(0.001)K 195.38 1.3052e-07 288900000.0 160592.0 172105.0 223954.0 220440.0 210069.0 229743.0 194367.0 243063.0 189659.0 189350.0 True False 211656.9154788921 227734.57555329113 220984.22363105605 169620.96376404975 180904.5454048849 215377.13389154235 211665.28646122868 205503.19838208644 199683.98754347762 182720.91413365412 1.1583617369825125 1.2463519933285307 1.2094084833081211 0.9283062345013106 0.9900593277054174 1.1787218497276197 1.1584075499228443 1.1246835062994915 1.0928359705852586 1.0 17.479282247920906 -5.622446448514754 24.400752186398822 1.0772514274240899 1.2089681053041903 0.3962491677738168 0.0768697472219199 11.563471620214905 2815.2738125950145 0.022758844502393148 0.03941947480377061 2.3853579083053633e-06 5.622446448514754 0.13171667788010044 S(ph)PGNTSQPPAFFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SPGNTSQPPAFFSK 14 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2;H7C184 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 S(1)PGNTSQPPAFFSK;S(0.995)PGNT(0.004)S(0.001)QPPAFFSK;S(1)PGNTSQPPAFFSK;S(0.998)PGNT(0.002)SQPPAFFSK;S(0.972)PGNT(0.024)S(0.004)QPPAFFSK;S(0.995)PGNT(0.004)S(0.001)QPPAFFSK 174.39 4.6284e-05 286138500.0 148425.0 176219.0 185962.0 162445.0 198523.0 157994.0 187305.0 150545.0 149428.0 132429.0 True False 173550.42097262395 193712.85772920086 190396.0393448122 153343.7333037959 159623.84325927988 149708.51650745873 169562.11442923246 146593.35326561285 151613.10180999798 156437.32939261245 1.1093926343952254 1.2382777082766327 1.2170754901278915 0.9802246938066008 1.0203692678661767 0.956987165970685 1.083898038195734 0.9370739952847568 0.9691619155009541 1.0 17.255225286977243 -5.763293257263407 24.999768631374483 0.9933947193702661 1.1932515486575566 0.771155698742295 0.04883399162653495 20.873526511003597 281488.422957155 0.013306696149123366 0.020940885351307358 1.7246729136633558e-06 5.763293257263407 0.19985682928729043 S(ph)PGNTSQPPAFFSK ddPTM_PC-9_Lapatinib_30min_R1 4 SPGNTSQPPAFFSK 14 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2;H7C184 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 S(0.993)PGNT(0.007)SQPPAFFSK;S(1)PGNTSQPPAFFSK;S(1)PGNTSQPPAFFSK;S(1)PGNTSQPPAFFSK 165.89 0.00015692 280896000.0 184106.0 165021.0 192691.0 160282.0 185150.0 168337.0 165895.0 170300.0 172168.0 146556.0 True False 181480.61467909478 164638.9040133598 176848.68978876987 172069.672965078 174259.84101890534 161137.61892271313 174484.23136953104 178212.7597107156 152776.6268305858 171888.00932640512 1.0558072979626745 0.9578265794021752 1.0288599564437604 1.0010568720842412 1.013798703596574 0.9374570079331267 1.0151041486448065 1.0367957625962154 0.8888149175110409 1.0 17.391109382320316 -1.5228787452879995 0.31189932377411045 0.9789883091681469 1.4141749701759605 0.1188038658166306 0.045368013070942445 150.27857293736756 2.1458061275926243 0.04301105185747905 36.97795685611823 0.02999999999947073 1.5228787452879995 0.43518666100781356 S(ph)PGNVNNTIVVPLLEDGR ddPTM_PC-9_AZD4547_30min_R2 2 SPGNVNNTIVVPLLEDGR 18 0 Q9Y4X4;Q9Y4X4-2;Q9Y4X4-3 Q9Y4X4 KLF12 Krueppel-like factor 12 1 S(1)PGNVNNTIVVPLLEDGR;S(1)PGNVNNTIVVPLLEDGR 131.31 4.082e-05 4020400.0 4127.8 5845.7300000000005 6993.0599999999995 11391.87 6974.639999999999 7400.55 4744.42 10325.599999999999 4560.2 7262.91 True False 5440.354536426279 7735.247903019322 6900.327455215767 8765.650374137014 6006.331627049823 6937.792438599023 5166.664188840604 8730.015778683177 4801.242862167185 7008.637731557752 0.7762356601668862 1.1036735239131945 0.984546172809832 1.25069246119941 0.8569898826422642 0.9898917170965001 0.7371852258216594 1.2456080786391035 0.6850465163220888 1.0 12.774918339609124 S(ph)PGNVNNTIVVPLLEDGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGNVNNTIVVPLLEDGR 18 0 Q9Y4X4;Q9Y4X4-2;Q9Y4X4-3 Q9Y4X4 KLF12 Krueppel-like factor 12 1 S(1)PGNVNNTIVVPLLEDGR 95.666 0.0066814 0.0 622.05 0.0 386.14 0.0 0.0 824.83 779.89 0.0 436.85 0.0 True False 727.3507789524721 0.0 395.34704204410497 0.0 0.0 781.5744627697718 706.0131732853602 0.0 443.23810481099594 0.0 0.0 S(ph)PGPAADGPIDLSK ddPTM_PC-9_AZD4547_30min_R2 3 SPGPAADGPIDLSK 14 0 Q8IX07 Q8IX07 ZFPM1 Zinc finger protein ZFPM1 1 S(1)PGPAADGPIDLSK;S(1)PGPAADGPIDLSK;S(1)PGPAADGPIDLSK 141.82 0.00013306 27740200.0 69340.0 63839.0 72423.0 92443.0 83656.0 87215.0 77410.0 102773.0 80934.0 76354.0 True False 91388.67763840243 84473.70831031381 71462.6236996525 71131.69458011273 72041.80840767131 81761.43226279305 84299.3400369596 86891.794338596 85212.00600996424 73680.86970034879 1.2403311471494454 1.1464808796890997 0.969893867842255 0.9654024832958236 0.9777545881401327 1.109669750035619 1.1441143458240226 1.1792992494791992 1.1565010884984284 1.0 16.16900247009074 -6.984712009522341 24.062143814010593 1.1337734042316772 1.0534395006480823 0.08144486020849429 0.09199738576928529 331.1786898450015 521246.873504755 0.03505926143142841 0.030906989549436957 1.0358288204670418e-07 6.984712009522341 -0.08033390358359482 S(ph)PGPAADGPIDLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPGPAADGPIDLSK 14 0 Q8IX07 Q8IX07 ZFPM1 Zinc finger protein ZFPM1 1 S(1)PGPAADGPIDLSK;S(1)PGPAADGPIDLSK;S(1)PGPAADGPIDLSK;S(1)PGPAADGPIDLSK 161.49 0.00016779 31883400.0 58819.0 75799.0 77286.0 79305.0 85003.0 65089.0 77521.0 62696.0 67086.0 57460.0 True False 68775.89497179553 83323.8237818608 79128.79134878718 74861.79796027891 68347.27234914116 61675.618257364105 70177.64967656243 61050.29643190304 68067.00583575704 67877.0431468902 1.0132423538685997 1.2275700283753197 1.1657666227084686 1.1029030507158843 1.0069276618492848 0.9086373742576586 1.0338937352455613 0.8994248069967685 1.0027986294048747 1.0 16.050636099258682 -6.254838249887506 2.770062299114779 0.9661194401014911 1.1432854413491809 0.5868968710011176 0.06318873866852966 0.1758272366536319 2.699257097620778 0.019567637188858376 0.024703181622547934 5.561113387015058e-07 6.254838249887506 0.17716600124768977 S(ph)PGPAADGPIDLSK ddPTM_PC-9_Lapatinib_30min_R1 3 SPGPAADGPIDLSK 14 0 Q8IX07 Q8IX07 ZFPM1 Zinc finger protein ZFPM1 1 S(1)PGPAADGPIDLSK;S(1)PGPAADGPIDLSK;S(1)PGPAADGPIDLSK 138.19 8.298700000000001e-05 29350500.0 80906.0 76472.0 83418.0 79712.0 90884.0 87421.0 83180.0 78649.0 86534.0 81228.0 True False 79752.26560365655 76294.93378242555 76559.69404279192 85574.28639143675 85538.38180481874 83682.20761830434 87486.65339713413 82303.31966229039 76787.62967658271 95268.1515704933 0.8371345962836717 0.8008440651435481 0.8036231708152947 0.8982465281497184 0.8978696489301039 0.8783859688553316 0.9183200466779154 0.8639122131113289 0.8060157398956566 1.0 16.539706376993593 -14.522878745280336 0.13416257115520394 1.4305267173399736 0.8079291418565689 0.503010844410863 0.041871839823928204 133.2964193596339 1.1107423499758065 15.761305883758867 0.317972036432473 3.0000000000000132e-15 14.522878745280336 -0.6225975754834047 S(ph)PGPGPDLYSAPIFSSNYSSR ddPTM_PC-9_AZD4547_30min_R2 2 SPGPGPDLYSAPIFSSNYSSR 21 0 Q8NEA6;Q8NEA6-2 Q8NEA6 GLIS3 Zinc finger protein GLIS3 1 S(1)PGPGPDLYSAPIFSSNYSSR;S(1)PGPGPDLYSAPIFSSNYSSR 189.84 2.1456e-15 6256200.0 4223.9 1853.24 3355.7 7444.0 4139.0 3732.7 4676.700000000001 6823.5 5528.200000000001 4274.5 True False 5567.012337422101 2452.2635879165696 3311.201225424571 5727.9008086535305 3564.371294340528 3499.2936789236696 5092.917240031625 5769.084863431152 5820.409365956022 4124.851056056544 1.349627480305749 0.5945096088538508 0.802744433780879 1.3886321544248776 0.864121212111875 0.8483442508271022 1.2346911854074496 1.3986165282163026 1.4110592811369225 1.0 12.01012631079191 -7.391907345099733 5.205077822032964 1.3054496044922705 0.9643624240261582 0.23434079686420728 0.2507790920642727 0.30595325965862125 11.65513811338418 0.1076916637097082 0.07123248362695586 4.0559505821740826e-08 7.391907345099733 -0.3410871804661123 S(ph)PGPGPDLYSAPIFSSNYSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGPGPDLYSAPIFSSNYSSR 21 0 Q8NEA6;Q8NEA6-2 Q8NEA6 GLIS3 Zinc finger protein GLIS3 1 S(1)PGPGPDLYSAPIFSSNYSSR 174.72 1.7857e-12 2765300.0 591.8 2525.6 961.05 1042.8 1266.7 1283.0 2204.1 2124.9 1182.7 727.74 True False 691.980051417206 2776.324876891082 983.9650768024208 984.3752968032155 1018.4992280820334 1215.7172214075827 1995.3116916978822 2069.123626517654 1199.9947500514254 859.6735012133299 0.8049335595904213 3.2295108235540817 1.1445799776469412 1.1450571588095753 1.184751218508584 1.4141615621416015 2.3210110453349206 2.4068714734109227 1.3958726753328692 1.0 9.74764502677808 -7.219249296089312 24.97036640009439 1.8981787560673529 1.5214945948938952 0.026467955318061787 0.7304832366049715 1596.0801422252214 944647.173826027 0.2794580287088426 0.21646531101338848 6.036020469702741e-08 7.219249296089312 -0.3766841611734577 S(ph)PGPGPDLYSAPIFSSNYSSR ddPTM_PC-9_Lapatinib_30min_R1 1 SPGPGPDLYSAPIFSSNYSSR 21 0 Q8NEA6;Q8NEA6-2 Q8NEA6 GLIS3 Zinc finger protein GLIS3 1 S(1)PGPGPDLYSAPIFSSNYSSR 126.25 1.0303e-05 2939300.0 2431.3 2085.7 5049.6 1787.6 2226.4 4617.0 4056.3 1935.3 1821.8 2978.1 True False 2396.6292161541874 2080.8706897950246 4634.441380019686 1919.0660672587876 2095.447529270814 4419.54167275267 4266.3153663716685 2025.2211031599993 1616.609699595517 3492.8606169311875 0.6861508313663703 0.5957497071907979 1.326832613232499 0.5494253214561052 0.5999230313151932 1.265307195863905 1.221438767321908 0.5798173260458787 0.4628325824853164 1.0 11.770193357605482 S(ph)PGPGPSQSPR ddPTM_PC-9_AZD4547_30min_R2 1 SPGPGPSQSPR 11 0 Q9P1Y5;Q9P1Y5-2 Q9P1Y5 CAMSAP3 Calmodulin-regulated spectrin-associated protein 3 1 S(1)PGPGPSQSPR 124.38 0.00051456 6384600.0 3019.0 2784.4 2650.5 5347.9 6197.0 2430.1 0.0 5685.4 1483.8 2510.1 True False 3978.979200899011 3684.4028480903125 2615.3526381940637 4115.024279231357 5336.653518006338 2278.145462842557 0.0 4806.852067494901 1562.2306387622625 2422.2221630149784 1.6426978753865882 1.5210837818048357 1.0797327669311276 1.6988632760709779 2.203205634682048 0.9405187920528781 0.0 1.9844802598584665 0.6449576189236619 1.0 11.242115477845028 -6.881710990978917 12.197280997505462 0.9154221557359858 1.5962645873495749 0.3193473386983444 0.5210317978888407 0.585198566193254 59.42967933316095 0.18450265660330623 0.1627294808570461 1.3130734164994036e-07 6.881710990978917 0.680842431613589 S(ph)PGPIVSR ddPTM_PC-9_AZD4547_30min_R2 2 SPGPIVSR 8 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 S(1)PGPIVSR;S(1)PGPIVSR 92.23899999999999 0.0081241 34243000.0 8348.3 19769.9 14103.3 10174.4 9896.8 14933.6 17685.1 15845.2 9638.7 14602.6 True False 11002.88574457277 26160.13355353423 13916.28102706748 7828.849272913016 8522.80015120303 13999.799631252039 19259.03963942166 13396.68842647311 10148.182004203954 14091.367418685526 0.7808245585863195 1.8564652227324085 0.9875749182874987 0.5555776838613798 0.6048242088912941 0.9935018522537375 1.366726100256506 0.9507018040498147 0.7201701369838102 1.0 13.78252399633789 -5.5009451444878135 24.86366862580739 0.8859004398005116 1.344488765896027 0.2166441452320257 0.3248707498472926 984.3051400140423 1115794.7480008465 0.0860996083870058 0.1766828457608946 3.1554031555512753e-06 5.5009451444878135 0.45858832609551536 S(ph)PGPIVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPGPIVSR 8 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 S(1)PGPIVSR;S(0.999)PGPIVS(0.001)R 83.869 0.014445 28926000.0 12591.8 24255.0 19477.5 7495.8 8764.4 8367.1 8261.6 13393.7 14864.6 9635.8 True False 14723.343040613667 26662.876104289353 19941.917468830092 7075.83462771149 7047.078735771831 7928.31454656227 7479.001439195691 13042.129566798196 15081.966653939638 11382.694263049174 1.2934848903399787 2.3424046616839336 1.7519505494903884 0.6216309130502842 0.6191046313743362 0.6965235438414076 0.6570501909617513 1.1457858100551754 1.3249909296869324 1.0 13.474554460909294 -5.711315484918879 6.8720881710412325 0.8468531826215392 1.8621013914515818 0.6284974983402148 0.32637788849070765 0.12638837704370123 13.357179474090414 0.0910963773005411 0.15725344177483383 1.9439474251643775e-06 5.711315484918879 1.0152482088300427 S(ph)PGPIVSR ddPTM_PC-9_Lapatinib_30min_R1 1 SPGPIVSR 8 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 S(1)PGPIVSR 112.11 0.0037351999999999997 17294000.0 6822.0 6756.0 3683.5 7773.4 11617.0 2957.4 7245.9 4196.3 10155.0 3113.6 True False 6724.7170289984215 6740.356897087402 3380.6568487211894 8345.081767302227 10933.71089990076 2830.9188960361166 7621.05724753901 4391.275417346307 9011.236963109282 3651.781611388785 1.8414893727560526 1.8457721776314058 0.9257554827972075 2.285208332633167 2.9940757864057024 0.7752158253952948 2.0869422267123734 1.2025021988311864 2.467627564311623 1.0 11.834384774631742 -11.06279474799299 2.776534426662575 0.957508129565804 1.8055658507263046 0.12252056952946444 0.6604840291305102 76205883.00788315 78157868.40722492 24238697.8728026 0.16190588886929672 8.653768080618692e-12 11.06279474799299 0.8480577211605006 S(ph)PGPPALK ddPTM_PC-9_Lapatinib_30min_R1 1 SPGPPALK 8 0 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 S(1)PGPPALK 68.846 0.042481 64454000.0 61408.0 133820.0 124890.0 125710.0 134690.0 125500.0 122870.0 130260.0 124360.0 110400.0 True False 60532.31065915202 133510.14801187624 114622.02628934148 134955.13275626668 126767.79901072859 120132.6575547889 129231.60739247271 136312.35513750956 110353.26723114411 129482.4929012466 0.46749417085535 1.031105789055988 0.8852318465691044 1.0422654810885819 0.979034278459649 0.92779073728841 0.998062398219617 1.0527473798444082 0.8522639992366233 1.0 16.982397521290885 -4.757560034508365 24.99999825623614 0.9747074504105145 0.4674934428129513 0.851728387998828 0.06343381503081451 37.755983634249006 243279.8931390903 0.014732435992992053 0.10830322704932012 1.747591668147922e-05 4.757560034508365 -0.5072140075975633 S(ph)PGPPALKHPATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGPPALKHPATK 13 1 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 S(1)PGPPALKHPATK 76.165 0.0073938 18844000.0 92233.0 33439.0 60798.0 97063.0 108410.0 131430.0 98428.0 122170.0 129650.0 88143.0 True False 107846.22521521339 36758.60292934784 62247.65489769902 91624.8747924919 87167.83872769645 124537.57943070839 89104.18728299046 118963.16694981509 131545.88597629793 104122.62816039578 1.0357616506671499 0.3530318392724685 0.5978302315017402 0.8799708229737373 0.837165179824492 1.1960664231300846 0.8557619881216392 1.1425294294969024 1.263374621832038 1.0 16.66792410683236 -6.2968402943251345 1.4480022211396792 1.0883287818057714 0.6413063019555504 0.4491856658635428 0.19651742672054 0.35360496817847736 1.4889327612366698 0.07387137205203234 0.09918488015626542 5.048469137698982e-07 6.2968402943251345 -0.44702247985022103 S(ph)PGPPPPVGVK ddPTM_PC-9_AZD4547_30min_R2 3 SPGPPPPVGVK 11 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 S(1)PGPPPPVGVK;S(1)PGPPPPVGVK;S(1)PGPPPPVGVK 119.03 0.0010054 50774300.0 90942.0 100530.0 102911.0 95311.0 92099.0 105212.0 98241.0 113039.0 101808.0 95234.0 True False 119859.66428888954 133024.3565287026 101546.33289914703 73338.52149027087 79312.64359445953 98633.07700777371 106984.2586819652 95571.41992780732 107189.36303484853 91899.8866469734 1.3042416988969916 1.4474920631807282 1.104966900440582 0.7980262453641032 0.863033094906125 1.0732665796059722 1.1641391799854695 1.039951445151808 1.1663710037707502 1.0 16.487775461586608 -5.384072812250035 4.782788809770931 1.0148043322360079 1.3724660813297653 0.6044762144662026 0.11468244234843364 0.15406888784734615 5.280805822300069 0.03356106834068292 0.07275191585572556 4.129782577371051e-06 5.384072812250035 0.3576617490937575 S(ph)PGPPPPVGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPGPPPPVGVK 11 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 S(1)PGPPPPVGVK;S(1)PGPPPPVGVK;S(1)PGPPPPVGVK 111.86 0.0017601 64754500.0 116616.0 151849.0 140761.0 137511.0 168141.0 137672.0 154228.0 112225.0 110899.0 114748.0 True False 136356.7855290114 166923.56518492033 144117.27607906528 129806.70448667728 135194.97806026807 130452.23796229536 139618.40732597484 109279.21266221636 112520.68807470467 135550.90405533192 1.0059452312715709 1.2314456059753174 1.0631967162700484 0.9576233031517823 0.9973742263281508 0.9623855987640239 1.030007201346164 0.8061857899347433 0.8300991340402546 1.0 17.048475209683957 -6.17901066725323 0.6683420004102486 0.8947617324118565 1.1347393624651623 0.41987683828753863 0.08576857259769978 0.824743945045892 0.7644834415376903 0.05540800448050648 0.11533975409611905 6.622002383687239e-07 6.17901066725323 0.23997763005330575 S(ph)PGPPPPVGVK ddPTM_PC-9_Lapatinib_30min_R1 2 SPGPPPPVGVK 11 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 S(1)PGPPPPVGVK;S(1)PGPPPPVGVK 123.62 0.00055283 72302000.0 54429.0 71472.0 63313.0 58876.0 65681.0 69245.0 75138.0 74441.0 72041.0 59665.0 True False 53652.832478943834 71306.51097522661 58107.649535247576 63205.93744457845 61817.772713814426 66283.55276797895 79028.27798694248 77899.80062023128 63926.98395463857 69978.01575138497 0.7667098288348075 1.0189844654721487 0.8303700656744835 0.9032256311629915 0.8833884763671791 0.9472053766638432 1.1293300780020816 1.1132039081672522 0.9135295316425625 1.0 16.09461413663618 -7.036371564378319 5.0231124844491974 1.0484514466825403 0.8885496292872122 0.45135186893472545 0.08178688130967449 0.1787550013179965 11.274925490478363 0.030167176327696308 0.024033515802843904 9.196624099869998e-08 7.036371564378319 -0.15990181739532816 S(ph)PGQMTVPLCIGVSTDK ddPTM_PC-9_Lapatinib_30min_R1 1 SPGQMTVPLCIGVSTDK 17 0 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3 C9JWC4 HJURP Holliday junction recognition protein 1 S(0.993)PGQMT(0.007)VPLCIGVSTDK 99.09200000000001 0.0012916 2798200.0 6378.6 6833.8 7038.0 6650.1 6477.5 8097.2 6520.9 6172.8 6001.7 5722.0 True False 6287.639994308019 6817.976755967424 6459.362807465652 7139.170538083282 6096.506185254987 7750.9016314951095 6858.520294991254 6459.610822914306 5325.725345297186 6711.040075914255 0.9369099160760777 1.0159344421793817 0.9624980233165548 1.0637949494156018 0.9084294112823416 1.1549478983612227 1.0219757619398373 0.9625349796520628 0.7935767459370529 1.0 12.712320657061175 -8.015811709370533 11.178836758414214 0.8904987312601272 1.0101491916001422 0.2398483987046074 0.079614010781959 0.7499634049328009 518.8880024391839 0.047250036731710444 0.01956882047851602 9.642469873043744e-09 8.015811709370533 0.11965046034001492 S(ph)PGREEVAR ddPTM_PC-9_Lapatinib_30min_R1 1 SPGREEVAR 9 1 A0A494BZV2;A0A1W2PPU9 A0A494BZV2 1 S(1)PGREEVAR 54.471000000000004 0.044805000000000005 5170600.0 1930.5 4257.6 6122.7 5169.2 5058.8 3241.4 3638.8 4491.0 5114.2 4085.8 True False 1902.9707159896573 4247.741788786165 5619.315240305475 5549.360211945699 4761.25132998347 3102.772878072454 3827.1992592148604 4699.66825520155 4538.184941086503 4792.025086013715 0.3971120104408007 0.8864189382446834 1.1726389447973335 1.1580407264858414 0.9935781312748001 0.6474867769637493 0.7986601051787371 0.9807269725941705 0.9470286276947748 1.0 12.226419745245558 -4.7732687705139645 4.481812597632003 0.9570002608287098 0.35595285010732247 0.5719981160196207 0.14562533694819763 0.16054848790136592 7.061468808711681 0.04149721111979459 0.30630211517741474 1.68550959631838e-05 4.7732687705139645 -0.6010474107213873 S(ph)PGSISYLPSFFTK ddPTM_PC-9_AZD4547_30min_R2 1 SPGSISYLPSFFTK 14 0 O75376-2;O75376;A0A088AWL3;E7EVK1;J3KS29;J3QKP0 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 S(0.751)PGS(0.246)IS(0.002)Y(0.001)LPSFFTK 77.387 0.015188 1498400.0 2367.2 935.1 3156.0 4634.7 4056.5 3567.3 2825.5 4616.6 3716.9 4217.8 True False 3119.9203591812334 1237.3527881228465 3114.149377906232 3566.2415204011995 3493.3249952868673 3344.2361670705927 3076.9640262812163 3903.2105489142323 3913.367745798257 4070.1361057984036 0.7665395647915871 0.30400771766823403 0.7651216806901734 0.8761971166813451 0.8582821076450493 0.8216521708712202 0.7559855361833495 0.9589877211608807 0.9614832634769115 1.0 11.990861323840887 -5.478791348347898 6.804253868616286 0.8749447027617412 0.5326274876440551 0.5594874980239806 0.12431814519380499 0.15308582041865818 18.738880415366246 0.031195606752344285 0.06410005141164589 3.320539506332114e-06 5.478791348347898 -0.3423172151176861 S(ph)PGSISYLPSFFTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGSISYLPSFFTK 14 0 O75376-2;O75376;A0A088AWL3;E7EVK1;J3KS29;J3QKP0 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 S(1)PGSISYLPSFFTK 131.96 1.4745999999999999e-05 2557200.0 4923.6 3764.9 6368.4 6451.3 8355.1 6143.3 5775.3 5758.4 7146.1 3949.7 True False 5757.068234467312 4138.654390642717 6520.246808291492 6089.854576396801 6717.9781325872 5821.134533338433 5228.221774448887 5607.248101529133 7250.5981934070205 4665.7493441920005 1.2339000254340287 0.8870288747496863 1.3974704441437686 1.3052254047846676 1.439849772673675 1.2476312171772954 1.1205535035775254 1.201789399276051 1.5540050822560112 1.0 12.187893088854203 -5.2716946945413135 24.9899657246467 1.2898079903275335 1.060464438991312 0.21642764142770066 0.16925226207137903 878.2816314199085 2140183.4005010775 0.04283608877372178 0.09078867469063052 5.349402858782556e-06 5.2716946945413135 -0.22934355133622142 S(ph)PGSISYLPSFFTK ddPTM_PC-9_Lapatinib_30min_R1 1 SPGSISYLPSFFTK 14 0 O75376-2;O75376;A0A088AWL3;E7EVK1;J3KS29;J3QKP0 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 S(0.998)PGS(0.002)ISYLPSFFTK 96.70700000000001 0.0028829 1242400.0 7913.7 7856.9 6327.6 5910.3 6964.5 7585.7 6335.5 7525.5 8053.0 5675.8 True False 7800.849186805156 7838.707830776497 5807.36915324235 6344.963178182826 6554.86180273382 7261.277294130373 6663.521190160419 7875.162203188436 7145.986338150566 6656.854467471889 1.1718521450218407 1.177539312160064 0.8723893817447157 0.9531473474727303 0.984678549720976 1.090797061827315 1.0010014824150215 1.183015528080071 1.0734779276111226 1.0 12.700624912982514 -7.715193851704279 24.999772101178 1.096186765401719 1.0320295197338705 0.04662470602655 0.09818156469241442 346.233708276993 187169.28538405677 0.049327690176207376 0.028479243614856653 1.926664735073716e-08 7.715193851704279 -0.06415724566784853 S(ph)PGSNSKVPEIEVTVEGPNNNNPQTSAVR ddPTM_PC-9_AZD4547_30min_R2 3 SPGSNSKVPEIEVTVEGPNNNNPQTSAVR 29 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347 A0A494C1K3 GTF2I General transcription factor II-I 1 S(0.484)PGS(0.376)NS(0.125)KVPEIEVT(0.015)VEGPNNNNPQTSAVR;S(0.495)PGS(0.495)NS(0.01)KVPEIEVTVEGPNNNNPQTSAVR;S(0.395)PGS(0.302)NS(0.302)KVPEIEVTVEGPNNNNPQTSAVR 107.09 1.0877e-11 97771300.0 81773.3 19845.8 89077.9 360193.0 253279.7 94553.9 47279.95 94368.3 56228.9 104689.9 True False 107775.50840969691 26260.566744228836 87896.66884353406 277156.0687763756 218116.1855808597 88641.42968563805 51487.77395660043 79785.8476028037 59201.044860425514 101024.73846612572 1.0668229390748165 0.25994194236923646 0.8700509417602343 2.7434475256702386 2.159037369386465 0.8774230058052576 0.5096551076335093 0.78976544571364 0.5860054255946034 1.0 16.62434909109937 -6.980588649555421 24.908690674054252 0.7023656435642724 1.4103903031871612 0.21141163116231498 0.6494576633457263 421.36903957261273 540699.8896545413 0.26238572127116644 0.23137211549522743 1.0457102150186174e-07 6.980588649555421 0.7080246596228887 S(ph)PGSNSKVPEIEVTVEGPNNNNPQTSAVR ddPTM_PC-9_Lapatinib_30min_R1 3 SPGSNSKVPEIEVTVEGPNNNNPQTSAVR 29 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347 A0A494C1K3 GTF2I General transcription factor II-I 1 S(0.55)PGS(0.339)NS(0.111)KVPEIEVTVEGPNNNNPQTSAVR;S(0.516)PGS(0.407)NS(0.077)KVPEIEVTVEGPNNNNPQTSAVR;S(0.941)PGS(0.055)NS(0.004)KVPEIEVTVEGPNNNNPQTSAVR 108.49 8.6047e-12 82643600.0 761048.0 74255.4 149550.0 104921.0 85174.6 85742.0 21807.399999999998 31577.9 131371.0 47162.6 True False 750195.3159608884 74083.46618353818 137254.57627969424 112637.24034619544 80164.79748770656 82075.01453436422 22936.480467572295 33045.12451479158 116574.61458204112 55314.59256978572 13.562340082581839 1.3393114319711092 2.4813447935376516 2.0363024495586877 1.4492522454462526 1.4837859364292914 0.41465514617386523 0.5974033791011181 2.1074839236132643 1.0 15.755372508307214 -4.7611406857610605 24.999977179618558 1.4434792717662321 13.562353567968705 0.9717169728944128 0.6207266137964401 1.1346716758427493 94815.22364223356 0.16842763241540484 0.9550631226317025 1.733242438624799e-05 4.7611406857610605 12.118874296202472 S(ph)PGSPPGPELPIETALDDR ddPTM_PC-9_Lapatinib_30min_R1 1 SPGSPPGPELPIETALDDR 19 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3;B1AP52 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.989)PGS(0.011)PPGPELPIETALDDR 138.98 0.00014727 3327700.0 6435.9 8496.5 7783.7 9143.8 10586.0 8577.0 6740.1 11629.0 9134.7 7762.1 True False 6344.122885800486 8476.826876273402 7143.754231950891 9816.265554822612 9963.352292876772 8210.181703963546 7089.069398437418 12169.32579375169 8105.853893344588 9103.768642651881 0.6968677626623512 0.9311338204003552 0.7847029633949433 1.078263952011327 1.09442063874489 0.9018442829816864 0.7786961286806613 1.3367349579532843 0.8903844343504093 1.0 13.152248179044282 -5.755885886499834 24.999414343653754 1.0146970540192748 0.8169247061435174 0.2833604468465577 0.15056643006608345 187.01158035838904 841833.387118537 0.04096383167580963 0.06846693379509784 1.754341405094668e-06 5.755885886499834 -0.19777234787575737 S(ph)PGSPPGPELPIETALDDRER ddPTM_PC-9_AZD4547_30min_R2 1 SPGSPPGPELPIETALDDRER 21 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3;B1AP52 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.607)PGS(0.393)PPGPELPIETALDDRER 100.85 8.8379e-05 5069600.0 8361.6 7471.0 11239.0 16120.0 12248.0 10722.0 6194.5 10180.0 9036.4 10323.0 True False 11020.414867915595 9885.85464663221 11089.963516567861 12403.78305151732 10547.57661586924 10051.551645034315 6745.798499663417 8606.914913128028 9514.045655823766 9961.594912076664 1.1062902040470748 0.9923967731961644 1.1132718821082808 1.2451603544408272 1.0588240847941104 1.0090303544514336 0.6771805678913259 0.864009728270889 0.955072530031278 1.0 13.282161029719903 -7.0096991171883225 4.762232742832339 0.8591231232457546 1.1012146885589336 0.541512784606801 0.09870832558240812 0.1459041971140704 8.960353097419757 0.038332684939987295 0.031413140066134854 9.77914493573938e-08 7.0096991171883225 0.242091565313179 S(ph)PGSPPGPELPIETALDDRER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPGSPPGPELPIETALDDRER 21 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3;B1AP52 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.768)PGS(0.232)PPGPELPIETALDDRER;S(0.499)PGS(0.499)PPGPELPIET(0.002)ALDDRER 66.31 0.0019034000000000002 10635100.0 30553.0 22347.9 34938.0 39314.0 44894.0 36785.0 40092.0 43990.0 33234.0 26613.0 True False 35725.019450743275 24566.451819874193 35771.05442310285 37111.36403770769 36097.34297427555 34855.92984370846 36294.19551905608 42835.30911125772 33719.98437744909 31437.72623160792 1.1363741508387095 0.7814322078794218 1.137838473417907 1.1804722696641914 1.1482173586072768 1.1087293523366786 1.1544790247128431 1.3625447589842077 1.0725961581644716 1.0 14.940209256401435 -5.454297894540123 13.079404423902737 1.1605168433157789 0.9589352499600323 0.279427548496457 0.11856258022327681 1.7676200187664186 335.2822464957503 0.029216995180302234 0.06081715896484081 3.513193782296895e-06 5.454297894540123 -0.20158159335574655 S(ph)PGSPPGPELPIETALDDRER ddPTM_PC-9_Lapatinib_30min_R1 1 SPGSPPGPELPIETALDDRER 21 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3;B1AP52 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.833)PGS(0.167)PPGPELPIETALDDRER 121.65 7.691199999999999e-07 2638300.0 6153.3 8884.0 8097.2 5780.9 8350.2 8097.9 6423.0 6960.7 10598.0 5013.0 True False 6065.55281362298 8863.429643831336 7431.479472095884 6206.046670517081 7859.057653124846 7751.571694126892 6755.551512019632 7284.119533284669 9404.34163811247 5879.490370597373 1.0316460154363178 1.5075166528303687 1.263966603170204 1.0555415995836608 1.3366902839788721 1.3184087744903152 1.1490029043679255 1.2389032168011838 1.5995164623693332 1.0 12.521475393520337 S(ph)PGSPVCR ddPTM_PC-9_AZD4547_30min_R2 1 SPGSPVCR 8 0 Q86VQ1;H7C0Q2;H7C2L5 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 S(0.994)PGS(0.006)PVCR 82.645 0.039173 0.0 16994.0 12659.0 14448.0 24890.0 15180.0 19292.0 14383.0 18250.0 12950.0 16026.0 True False 22397.73850284126 16750.774189762706 14256.410079844498 19151.995046666645 13072.519025873202 18085.668190263194 15663.059136436998 15429.881843279625 13634.510562051015 15464.934617934767 1.4482918328582188 1.0831454903363602 0.9218538863598728 1.2384142267537281 0.8453006332605463 1.1694629584330185 1.0128112095781165 0.9977334029841619 0.8816403624648371 1.0 13.916713113618032 -4.773556341060719 3.799571995470913 1.0156757500563234 1.4957161794606462 0.5697873839829539 0.11394959025107243 0.17870767812137017 4.587742024925929 0.026945223449228933 0.2440129653877677 1.6843938960334582e-05 4.773556341060719 0.4800404294043228 S(ph)PGSQAPDEGAGGALR ddPTM_PC-9_AZD4547_30min_R2 2 SPGSQAPDEGAGGALR 16 0 P10075 P10075 GLI4 Zinc finger protein GLI4 1 S(0.998)PGS(0.002)QAPDEGAGGALR;S(1)PGSQAPDEGAGGALR 141.1 5.3468e-07 0.0 3885.5 3891.2999999999997 5134.5 11532.4 8003.0 10441.1 5203.299999999999 8738.5 3713.2 6712.7 True False 5121.008176579367 5149.086626481053 5066.4131751773 8873.783353803865 6891.921591835521 9788.216366439823 5666.383619872251 7388.165615753371 3909.472171351955 6477.690416186863 0.7905608091091644 0.794895448169951 0.7821326506306979 1.3698992671260566 1.0639473560844388 1.5110657869632682 0.8747536939574532 1.1405555284475088 0.6035287147380057 1.0 12.661263804708641 -5.714363342210972 24.99815766612639 1.0950656887995833 0.7897652718533913 0.24292357761123995 0.2347117397006024 168.06888731696705 89246.00345070781 0.06313932572247939 0.10936011874921975 1.930352657344824e-06 5.714363342210972 -0.30530041694619203 S(ph)PGSQAPDEGAGGALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGSQAPDEGAGGALR 16 0 P10075 P10075 GLI4 Zinc finger protein GLI4 1 S(0.999)PGS(0.001)QAPDEGAGGALR 153.92 6.9678e-11 0.0 0.0 5901.8 2596.4 3531.8 3452.1 1480.8 4075.7 2774.9 3683.5 0.0 True False 0.0 6487.691700362608 2658.308022901834 3333.9246962500924 2775.6857861072 1403.1442412005842 3689.6201904873033 2702.0618152495817 3737.364219002642 0.0 0.0 S(ph)PGSQAPDEGAGGALR ddPTM_PC-9_Lapatinib_30min_R1 3 SPGSQAPDEGAGGALR 16 0 P10075 P10075 GLI4 Zinc finger protein GLI4 1 S(0.999)PGS(0.001)QAPDEGAGGALR;S(1)PGSQAPDEGAGGALR;S(0.981)PGS(0.019)QAPDEGAGGALR 119.04 0.0012565 0.0 3895.3999999999996 6126.5 8052.200000000001 4655.4 7537.1 4916.4 5471.0 7620.0 4655.0 5421.9 True False 3839.85088167113 6112.314465661036 7390.179198390867 4997.7736459591415 7093.7825965087395 4706.13703268816 5754.261610191407 7974.053018177653 4130.704880676877 6359.0681907723765 0.6038386075562336 0.9611965593529246 1.1621481287328752 0.7859286134423585 1.1155380605609018 0.7400670808212467 0.9048906911458188 1.2539656407127031 0.6495770695887378 1.0 12.63459966415916 -4.7612055268148 24.75401714470098 0.9588273247568531 0.603838256468208 0.24792352558429398 0.18193403298512245 6.696603911710352 707172.1145926543 0.04231523937119311 0.23892363767932293 1.7329836813033685e-05 4.7612055268148 -0.35498906828864507 S(ph)PGSSWQEYGPSDTCGSR ddPTM_PC-9_AZD4547_30min_R2 4 SPGSSWQEYGPSDTCGSR 18 0 Q5JSZ5;A0A494C0D3 Q5JSZ5 PRRC2B Protein PRRC2B 1 S(0.928)PGS(0.017)S(0.054)WQEYGPSDTCGSR;S(0.995)PGS(0.002)S(0.004)WQEYGPSDTCGSR;S(0.964)PGS(0.027)S(0.008)WQEYGPSDTCGSR;S(0.755)PGS(0.194)S(0.05)WQEYGPSDTCGSR 206.8 3.1528e-20 21825800.0 8933.71 15158.600000000002 21605.8 26074.4 14762.009999999998 20574.3 13120.800000000003 22431.9 13694.599999999999 14373.800000000001 True False 11774.44394728834 20058.321007420574 21319.292975021064 20063.349925464216 12712.559722340613 19287.785768553393 14288.525781642393 18965.565288781607 14418.468597919984 13870.577637044225 0.8488791350579568 1.4461056729065638 1.5370155110255477 1.4464682330086183 0.9165126395593729 1.390553895682138 1.0301319927356125 1.3673233938095102 1.039500226682161 1.0 13.759740249168173 -6.232341531696211 24.9924591740731 1.1510037066992023 1.3441804799102821 0.14235868184071787 0.2263559243397538 1439.702745445699 1236576.3890469274 0.0656392871062159 0.08472567164606148 5.856774032626649e-07 6.232341531696211 0.19317677321107984 S(ph)PGSSWQEYGPSDTCGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPGSSWQEYGPSDTCGSR 18 0 Q5JSZ5;A0A494C0D3 Q5JSZ5 PRRC2B Protein PRRC2B 1 S(1)PGSSWQEYGPSDTCGSR;S(1)PGSSWQEYGPSDTCGSR;S(0.993)PGS(0.007)S(0.001)WQEYGPSDTCGSR 229.48 3.0574e-35 12370600.0 15295.400000000001 21094.5 18181.9 17195.3 26803.2 23354.6 17884.499999999996 15993.4 14588.4 17694.6 True False 17884.609122079633 23188.622551306213 18615.425451239724 16231.903088914778 21551.305368381112 22129.843662576404 16190.350687432863 15573.590196408028 14801.727751458702 20902.49090962346 0.8556209496469916 1.1093712539604657 0.8905840711390633 0.7765535293902052 1.031040054583109 1.0587180139563115 0.7745656131336416 0.745059058451162 0.7081322420115979 1.0 14.35138725529245 -7.284190376122972 24.28821958988306 0.785694112136551 0.953327843039644 0.2626509680368464 0.11829890813395817 704.9426093857019 752569.6685187641 0.04958672836586626 0.03346148872445309 5.1976810248575015e-08 7.284190376122972 0.16763373090309297 S(ph)PGSSWQEYGPSDTCGSR ddPTM_PC-9_Lapatinib_30min_R1 3 SPGSSWQEYGPSDTCGSR 18 0 Q5JSZ5;A0A494C0D3 Q5JSZ5 PRRC2B Protein PRRC2B 1 S(1)PGSSWQEYGPSDTCGSR;S(1)PGSSWQEYGPSDTCGSR;S(0.993)PGS(0.006)S(0.001)WQEYGPSDTCGSR 188.09 8.822399999999999e-11 17542900.0 15848.900000000001 14443.2 15159.9 17149.0 17448.3 13730.1 11864.6 12548.9 15747.1 11686.3 True False 15622.89177966771 14409.757657787559 13913.511540906296 18410.194667386975 16422.025298677665 13142.895629426353 12478.890934066343 13131.967706011741 13973.495773685687 13706.261383984065 1.139836118835677 1.0513266348929795 1.0151208379233454 1.3431959417394093 1.1981403855224155 0.958897197508869 0.9104518427357646 0.958099903257106 1.0194972489007024 1.0 13.742547484705357 -6.770471520591365 24.852150478863066 0.9630868497277953 1.1473612879854216 0.5187401056053568 0.08663379510177081 161.39863826549418 444089.43759603845 0.033151103118141526 0.029661051954935458 1.6964008422384057e-07 6.770471520591365 0.18427443825762624 S(ph)PGSTPTTPTS(ph)SQAPQK ddPTM_PC-9_AZD4547_30min_R2 1 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-4;P35658-3;P35658-5 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 2 S(0.838)PGS(0.132)T(0.03)PT(0.249)T(0.125)PT(0.213)S(0.297)S(0.116)QAPQK 160.43 0.00036041 14550000.0 23089.0 24163.0 28348.0 28693.0 25390.0 26832.0 24173.0 29058.0 24642.0 22671.0 True False 30430.821718965624 31973.217216781453 27972.08699774586 22078.272152430927 21865.036763301752 25154.190798317555 26324.350170693975 24567.753786412017 25944.525812359945 21877.295190515353 1.3909773330735398 1.4614794442524628 1.2785898235661615 1.0091865543781986 0.9994396735470793 1.1497852261564245 1.203272613979565 1.1229794895789074 1.1859110363701584 1.0 14.41714676043832 -5.535992966514046 4.30898791792913 1.1042742802076837 1.4187155701036385 0.7711696372014011 0.07292189863389653 0.09654846616059444 4.312657548340245 0.021522771632392034 0.04168558808800285 2.910764258093933e-06 5.535992966514046 0.31444128989595477 S(ph)PGSTPTTPTSSQAPQK ddPTM_PC-9_AZD4547_30min_R2 1 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-4;P35658-3;P35658-5 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 S(0.498)PGS(0.498)T(0.003)PTTPTSSQAPQK 175.27 5.595e-06 24614000.0 39387.0 38457.0 47112.0 42901.0 46550.0 47013.0 39475.0 46132.0 42578.0 38223.0 True False 51911.246699506235 50887.47318237655 46487.26409756605 33010.83726384274 40087.33601148864 44073.26967804497 42988.19852679204 39003.3594079 44828.58615529019 36884.824404175735 1.4073876597777528 1.3796317050275986 1.2603357843911334 0.8949707039978636 1.0868246401886177 1.1948889655837815 1.1654711448734818 1.0574364942207621 1.2153666685265592 1.0 15.17073974705148 -5.529092139200153 24.93353641704123 1.0963385719087726 1.375128233701077 0.6548757911233241 0.09008560237758728 91.09143412545902 365536.69723198604 0.0252024912696889 0.043801043049303184 2.9573849660781377e-06 5.529092139200153 0.27878966179230447 S(ph)PGSTPTTPTSSQAPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-4;P35658-3;P35658-5 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 S(0.978)PGS(0.022)TPTTPTSSQAPQK;S(0.876)PGS(0.096)T(0.028)PTTPTSSQAPQK 279.29 5.5964999999999986e-83 60758000.0 59945.0 57364.0 63142.0 54998.0 55837.0 42879.0 46889.0 35249.0 33252.0 36371.0 True False 70092.50453228182 63058.71881453121 64647.54474736846 51916.64036592178 44896.14067925834 40630.349755834584 42447.33447303753 34323.75109940267 33738.24759339642 42964.7743873224 1.631394683942853 1.4676841601928188 1.5046638943004431 1.2083536130761297 1.0449523201151925 0.9456665450994051 0.9879566477035301 0.798881213479165 0.7852536892024633 1.0 15.390866698808328 -6.015134208915747 0.9400549335207434 0.8696991250118452 1.6144696079153427 0.9327637902590598 0.07416861388838551 0.14238139541989245 0.25571311087461535 0.03285203376012653 0.07147517313247363 9.65752388874516e-07 6.015134208915747 0.7447704829034975 S(ph)PGSTPTTPTSSQAPQK ddPTM_PC-9_Lapatinib_30min_R1 1 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-4;P35658-3;P35658-5 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 S(0.645)PGS(0.175)T(0.175)PT(0.004)TPTSSQAPQK 273.84 1.5476999999999997e-82 39032000.0 13687.0 21192.0 23259.0 21552.0 19088.0 14206.0 15560.0 15799.0 14417.0 11745.0 True False 13491.820870111598 21142.93122603259 21346.73480233639 23137.00597536439 17965.281368451888 13598.442495803436 16365.620664335278 16533.079217085124 12793.205642259618 13775.107600771224 0.9794348807377907 1.534865050698324 1.5496601130826198 1.6796243373132727 1.3041844673101552 0.9871750471874429 1.188057555602616 1.2002141613877115 0.9287191079032564 1.0 13.749775967637552 -6.564025949282944 5.433719846225408 1.0844004842113584 1.456362141542737 0.46648529526066573 0.18914719056079238 0.17380147308642102 12.519945232632086 0.06369080106454675 0.06452343732875727 2.7288147300776643e-07 6.564025949282944 0.37196165733137865 S(ph)PGVAAAVAEDGGLKK ddPTM_PC-9_AZD4547_30min_R2 2 SPGVAAAVAEDGGLKK 16 1 E9PLH8;E9PM78;H0YD80;E9PLS2;E9PQV9;E9PM04;Q9BTE7 E9PLH8 DCUN1D5 DCN1-like protein;DCN1-like protein 5 1 S(1)PGVAAAVAEDGGLKK;S(1)PGVAAAVAEDGGLKK 61.56100000000001 0.018782 14152700.0 79606.0 68017.0 65296.0 72198.0 68557.0 63522.0 63747.0 56145.0 58757.0 71574.0 True False 104919.0520923374 90002.16510507069 64430.13237635152 55553.86654798063 59039.043929959844 59549.95929825313 69420.35950569755 47469.08033374984 61862.77506520711 69068.21604543019 1.5190641672766823 1.3030909187790665 0.9328477853542947 0.8043333059513165 0.8547932364595376 0.8621904938022962 1.0050984878491103 0.6872782164016898 0.8956764573811543 1.0 16.075734340485106 -5.143140926918534 2.2706390446434854 0.8622032908322985 1.5194681626697424 0.8618258787493495 0.08725697419794276 0.11142924454443691 1.0210300919881052 0.023189784974157426 0.10612777921548056 7.192155574026467e-06 5.143140926918534 0.6572648718374439 S(ph)PGVAAAVAEDGGLKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGVAAAVAEDGGLKK 16 1 E9PLH8;E9PM78;H0YD80;E9PLS2;E9PQV9;E9PM04;Q9BTE7 E9PLH8 DCUN1D5 DCN1-like protein;DCN1-like protein 5 1 S(1)PGVAAAVAEDGGLKK 90.581 0.0015937999999999998 5494900.0 27569.0 30979.0 23730.0 26524.0 27660.0 23318.0 29655.0 22799.0 18227.0 21566.0 True False 32235.88718742977 34054.39038692147 24295.813196526167 25037.94627196824 22240.221558971385 22095.163031007047 26845.863716392516 22200.55040753729 18493.535392903785 25475.74508363793 1.2653560114374678 1.3367377588023233 0.9536841068538724 0.9828150733086559 0.872995921648447 0.8673019359578182 1.053781297789581 0.8714387090407743 0.7259271645319397 1.0 14.636836720749184 -5.306039341511499 4.848074230345808 0.9127178620623321 1.3032317969621627 0.7571477118913401 0.08732895579166768 0.08770977352674397 4.873778554560647 0.023540238389645675 0.053366894703580275 4.9426591080479315e-06 5.306039341511499 0.39051393489983066 S(ph)PGVAAAVAEDGGLKK ddPTM_PC-9_Lapatinib_30min_R1 2 SPGVAAAVAEDGGLKK 16 1 E9PLH8;E9PM78;H0YD80;E9PLS2;E9PQV9;E9PM04;Q9BTE7 E9PLH8 DCUN1D5 DCN1-like protein;DCN1-like protein 5 1 S(1)PGVAAAVAEDGGLKK;S(1)PGVAAAVAEDGGLKK 61.015 0.019788 16449600.0 53048.0 60192.0 47442.0 54848.0 52736.0 49386.0 51039.0 46877.0 47393.0 40627.0 True False 52291.52579218825 60052.62912218548 43541.50189141594 58881.70488756436 49634.172162965166 47273.87590438886 53681.54968425505 49055.07655290203 42055.10126958521 47649.32281792528 1.0974243221042508 1.2603039365670519 0.9137905707032628 1.2357301511410683 1.0416553526400423 0.9921206243586912 1.1265962769162483 1.0295020716317067 0.8825959905093222 1.0 15.540168090554275 -6.996860704650869 0.4777195150578452 0.9613371739762324 1.146133064619614 0.23429029902688392 0.10321154339767329 1.6023918274688005 0.7885724515492979 0.0970447791061601 0.11174737901510869 1.0072546833044672e-07 6.996860704650869 0.18479589064338153 S(ph)PGVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGVPR 6 0 H0Y4E4;P09848 REV__A8MXZ1 LCT Lactase-phlorizin hydrolase;Lactase;Phlorizin hydrolase 1 S(1)PGVPR 87.75399999999999 0.039466 9419800.0 7186.5 12869.0 16405.0 15389.0 16668.0 18102.0 15563.0 10075.0 14358.0 15618.0 True False 8403.032510155032 14146.549271741906 16796.157416308957 14526.804221811157 13402.025052239147 17152.699253250255 14088.759973637387 9810.541925344893 14567.958587332681 18449.419767980027 0.4554632403529 0.766774752249608 0.9103894663104584 0.7873854248263794 0.726419866900047 0.9297148348816746 0.7636424424625644 0.5317534127751606 0.7896160838952869 1.0 14.171287823964066 -4.765361645346241 5.340007379493281 0.7908199119870187 0.43863233086364384 0.4171004628151266 0.1222279067369613 0.1594456879557419 13.588939056843529 0.03091673515340083 0.20794085133820497 1.716478447340401e-05 4.765361645346241 -0.3521875811233749 S(ph)PGYEPR ddPTM_PC-9_AZD4547_30min_R2 3 SPGYEPR 7 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 S(1)PGYEPR;S(1)PGYEPR;S(1)PGYEPR 84.615 0.019837 102632000.0 105280.0 99869.0 138302.0 191592.0 148041.0 154031.0 114700.0 165859.0 123959.0 141763.0 True False 138756.85003996262 132149.7012052621 136468.02511507852 147423.4244668926 127488.06252366875 144399.41722032079 124908.07779665719 140229.30261065805 130511.21967268598 136799.92051929916 1.0143050486669498 0.9660071490072172 0.997573862594651 1.0776572377181661 0.9319308230568983 1.055551908745075 0.9130712746213597 1.0250685971040099 0.9540299378629683 1.0 17.061707866455606 -7.247617827438338 24.990381640003243 0.9751314947577873 1.004647592592722 0.10961459796359341 0.04717486624670656 2098.78314038183 3794758.5892289192 0.017116337942902845 0.013190773244595678 5.654343295878699e-08 7.247617827438338 0.029516097834934807 S(ph)PGYEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGYEPR 7 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 S(1)PGYEPR 80.438 0.025405 42208000.0 13495.0 10865.0 15116.0 19731.0 15285.0 14714.0 9193.5 15275.0 18518.0 8346.8 True False 15779.436961600533 11943.605395716517 15476.422767749225 18625.536038765094 12290.013974290581 13942.371937483387 8322.625124823962 14874.047435200308 18788.790717385873 9860.008766767558 1.600347153319374 1.2113179286383162 1.5696155179812195 1.8889979186977104 1.246450613280708 1.4140324078083113 0.8440788767728853 1.508522739384594 1.9055551736132452 1.0 13.267373214000209 S(ph)PGYEPR ddPTM_PC-9_Lapatinib_30min_R1 2 SPGYEPR 7 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 S(1)PGYEPR;S(1)PGYEPR 95.50200000000001 0.013106 51672000.0 110396.0 95643.0 107953.0 90145.0 99025.0 98425.0 91687.0 85697.0 107533.0 72732.0 True False 108821.73279585298 95421.54450978858 99077.52105063072 96774.56401490461 93200.54419064075 94215.59218988137 96434.10423206355 89678.79547227931 95421.50116730963 85303.62929070179 1.2756987445986039 1.1186106066437862 1.1614690004922252 1.1344718251683246 1.0925741960289577 1.104473431825614 1.130480672790964 1.0512893322119696 1.1186100985472456 1.0 16.380319502667604 -1.5228787452803376 0.163055552506541 1.015847574721981 1.7925833225503909 0.6634222039219955 0.03951186053483543 39.65979369469657 0.4165104884829744 0.10858401243804826 7.431559520418029 0.029999999999999995 1.5228787452803376 0.7767357478284098 S(ph)PGYESESSR ddPTM_PC-9_AZD4547_30min_R2 2 SPGYESESSR 10 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 S(1)PGYESESSR;S(0.999)PGYESESS(0.001)R 93.839 0.0065373 59988000.0 27071.0 31910.0 35209.0 47577.0 39907.0 34199.0 29474.0 43651.0 39335.0 37805.0 True False 35679.01488822031 42224.28346593947 34742.10565484807 36608.857707322575 34366.60189496192 32060.531123720255 32097.128901296255 36905.7409501917 41414.16779600591 36481.45845694642 0.9780040710358903 1.1574176376684733 0.9523222788872039 1.0034921643970596 0.9420292759271028 0.8788171438254443 0.879820332270314 1.0116300858351372 1.1352114073202644 1.0 15.154875786314832 -5.294583279582346 24.9313836074428 0.9687770294996638 1.0677109254917987 0.1700419808131849 0.08050074444219994 901.6390864145841 678226.2653893821 0.021962809059964856 0.04572372244227902 5.074774166786875e-06 5.294583279582346 0.09893389599213487 S(ph)PGYESESSR ddPTM_PC-9_Lapatinib_30min_R1 1 SPGYESESSR 10 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 S(1)PGYESESSR 122.18 0.0005605 28850000.0 15045.0 15524.0 20093.0 12169.0 14445.0 12119.0 12938.0 13627.0 16122.0 6127.0 True False 14830.455541084906 15488.055131791725 18441.031101222965 13063.948854593978 13595.373499962681 11600.698620768822 13607.866333879801 14260.1601678093 14306.170587813658 7186.043786285684 2.06378585799718 2.155296515358025 2.566228602227144 1.8179612096889908 1.8919135346640916 1.6143373135171197 1.8936520203021783 1.9844243358249947 1.9908270827846177 1.0 12.810982010715323 -5.861063036673407 8.961635796697045 1.788017345164518 2.2502043944287564 0.3814120543752856 0.29945368808068645 0.29824486066146333 24.136568404773133 0.08058502786211579 0.11981848502945924 1.3770095851584494e-06 5.861063036673407 0.46218704926423837 S(ph)PGYESESSRYESQNTELK ddPTM_PC-9_Lapatinib_30min_R1 2 SPGYESESSRYESQNTELK 19 1 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 S(0.814)PGY(0.07)ES(0.005)ES(0.041)S(0.041)RY(0.011)ES(0.015)QNT(0.002)ELK;S(0.821)PGY(0.174)ES(0.003)ES(0.001)S(0.001)RYESQNTELK 61.821000000000005 0.007843000000000001 12149800.0 33316.0 17053.9 32583.0 19469.7 17966.300000000003 26088.0 17502.7 17105.7 26228.0 17995.5 True False 32840.90773059388 17014.4127423385 29904.151514017245 20901.566687015234 16909.557557104854 24972.277054098256 18408.904164631163 17900.493269428014 23273.926446915815 21105.998197503493 1.5559987934841404 0.8061411065765672 1.4168555893060975 0.9903140562898163 0.8011730788030195 1.183183890210513 0.8722119651658383 0.8481235098155822 1.102716215036385 1.0 14.365365441990434 -4.748262346666893 24.9941635474923 1.0054381439671818 1.5560001223625133 0.45192407445297356 0.1828988644084502 611.3318529147032 1159504.5936383936 0.04470749508299494 0.8340170482073802 1.785408727318967e-05 4.748262346666893 0.5505619783953315 S(ph)PHEAGFCVYLK ddPTM_PC-9_AZD4547_30min_R2 4 SPHEAGFCVYLK 12 0 Q9NTZ6 Q9NTZ6 RBM12 RNA-binding protein 12 1 S(1)PHEAGFCVYLK;S(1)PHEAGFCVYLK;S(1)PHEAGFCVYLK;S(1)PHEAGFCVYLK 135.1 5.9372e-05 14976000.0 97427.3 107337.0 114359.9 101835.5 104088.7 130101.7 112808.59999999999 155721.4 125816.79999999999 108885.7 True False 128407.15478627 142031.58616056258 112843.4130045687 78358.89881779099 89637.78070674607 121966.42013213568 122848.34686078441 131658.23575178516 132467.21918791204 105073.64478522759 1.222068150854922 1.3517336954559602 1.073945928450685 0.7457521719928721 0.8530948068848977 1.1607708134750367 1.169164228688256 1.2530091253700864 1.2607083294643238 1.0 16.681041323510662 -9.419000325553535 15.184389092300355 1.0000085361083908 1.1140650741832034 0.038388881700171296 0.1787589144514679 0.0 0.0 0.1970770852948939 0.04779821406233581 3.81065537741331e-10 9.419000325553535 0.11405653807481264 S(ph)PHEAGFCVYLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPHEAGFCVYLK 12 0 Q9NTZ6 Q9NTZ6 RBM12 RNA-binding protein 12 1 S(1)PHEAGFCVYLK;S(1)PHEAGFCVYLK 95.094 0.0047038 3068200.0 12590.3 19831.4 16578.2 17655.6 17557.699999999997 16720.2 18798.4 14497.099999999999 14659.3 14405.7 True False 14721.58912024002 21800.13033084329 16973.48716117361 16666.413972227507 14117.394724004047 15843.363277770122 17017.679463369863 14116.566485947124 14873.664529829082 17017.339374541552 0.8650934670941544 1.281053979769419 0.9974230863942487 0.979378362587101 0.8295888336765552 0.931012946798973 1.0000199848413918 0.829540163432712 0.8740299645243327 1.0 14.054717871849036 -5.7534154633478405 2.7312260299818885 0.9090163366282344 1.0813888542314818 0.23063223107360165 0.11070761512006876 0.3190441745636894 4.856622992876915 0.0307397129927252 0.05531450745249859 1.7643491666205726e-06 5.7534154633478405 0.17237251760324734 S(ph)PHEAGFCVYLK ddPTM_PC-9_Lapatinib_30min_R1 4 SPHEAGFCVYLK 12 0 Q9NTZ6 Q9NTZ6 RBM12 RNA-binding protein 12 1 S(1)PHEAGFCVYLK;S(1)PHEAGFCVYLK;S(1)PHEAGFCVYLK;S(1)PHEAGFCVYLK 94.191 0.0049859 6514900.0 46130.6 39691.4 33355.8 25194.2 36109.9 33576.6 30766.200000000004 33191.0 34399.8 23710.3 True False 45472.76918468406 39599.49700193237 30613.4148811115 27047.065513387435 33985.98667679489 32140.607088877503 32359.12329582725 34733.175029702674 30525.33227804693 27808.59376301115 1.635205633632882 1.4240021390295745 1.1008616667927706 0.9726153628582024 1.2221397085529881 1.155779661596138 1.1636375277224145 1.249008681478244 1.0976942069846545 1.0 14.763243171252203 -5.05381359520643 2.912837185753404 1.1304615312924284 1.6239555070628329 0.8026304902733926 0.08402388638428285 0.11998190565311959 1.8915241575746424 0.022920733508460477 0.10198368580826002 8.834590110563825e-06 5.05381359520643 0.49349397577040444 S(ph)PHHYYR ddPTM_PC-9_AZD4547_30min_R2 2 SPHHYYR 7 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 S(1)PHHYYR;S(1)PHHYYR 71.37899999999999 0.023556 7535000.0 9715.599999999999 10488.7 17013.199999999997 20878.5 14068.2 16001.8 12077.3 21476.7 16007.900000000001 16738.1 True False 12804.958702966018 13878.967157292369 16787.5938517726 16065.284394609464 12115.073264808265 15001.204916387811 13152.156303169748 18157.96950046922 16854.04491322444 16152.10421368112 0.7927734079452008 0.8592668158701352 1.039344077383627 0.9946248601468212 0.750061608353578 0.92874616941126 0.814268910674167 1.1241860045138328 1.0434581581605178 1.0 13.979434503657124 -7.764085641405921 24.999998339309442 1.0628665755969875 0.8888192698147148 0.4436600824319341 0.0885693594308757 68.02507489530095 642625.8974317985 0.047648192356810226 0.024522918033780865 1.7215290617915146e-08 7.764085641405921 -0.17404730578227268 S(ph)PHHYYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPHHYYR 7 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 S(1)PHHYYR;S(1)PHHYYR;S(0.999)PHHY(0.001)YR 69.825 0.02582 13843700.0 11942.1 17735.0 28273.6 26403.7 30929.6 27411.699999999997 32631.8 30270.6 27728.899999999998 21021.1 True False 13963.661662773584 19495.613593468235 28947.7498522251 24924.38629095037 24869.166909991367 25974.182196460068 29540.679670226833 29476.028824351855 28134.38270457509 24832.05902706397 0.5623239558006392 0.7850985523278738 1.1657410213416262 1.0037180671882977 1.0014943538466525 1.045993897169434 1.1896186151148815 1.1870150917500042 1.1329863010518775 1.0 14.5999162715505 -5.03813142911356 2.921939414864291 1.0932235804124208 0.568882499964765 0.8425242786144173 0.07481230437278434 0.10770908991007988 1.7180290920465517 0.021556852730337098 0.09961988926404027 9.159432592732606e-06 5.03813142911356 -0.5243410804476558 S(ph)PHHYYR ddPTM_PC-9_Lapatinib_30min_R1 1 SPHHYYR 7 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 S(1)PHHYYR 71.692 0.023101 3624800.0 4883.3 4141.2 6267.1 3210.4 4439.0 4249.1 4078.8 4408.4 6896.3 3965.2 True False 4813.663246512459 4131.611305834571 5751.843229705595 3446.503525580451 4177.906747409785 4067.375898135884 4289.980306278323 4613.230357655427 6119.566072741557 4650.579536703116 1.0350673950466305 0.8884078367496427 1.2368013887970586 0.7410911905451988 0.8983626050123598 0.8745954920318004 0.9224614421538464 0.9919689194103825 1.3158717154378212 1.0 12.183194794996743 -8.05996698136769 8.451615883616606 1.1579913858409738 0.9407894698430038 0.26976863562295295 0.13983864472667162 0.47458548069534073 62.225215149123606 0.09136141679121085 0.03455949362856261 8.71029810276551e-09 8.05996698136769 -0.21720191599797 S(ph)PHKDLGHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPHKDLGHR 9 1 C9JAT7;O94888 C9JAT7 UBXN7 UBX domain-containing protein 7 1 S(1)PHKDLGHR 51.927 0.045427999999999996 2895700.0 2959.2 3760.1 3085.7 2867.7 5442.2 4438.6 2680.3 2944.5 3344.5 5204.1 True False 3460.134113135846 4133.377878364808 3159.274790582418 2707.032066208841 4375.839977159582 4205.832002291271 2426.402580308443 2867.209994955635 3393.40698532763 6147.562134367067 0.5628465459165448 0.6723604882751407 0.5139069311590921 0.44034236776161484 0.7118008539835774 0.6841463185510837 0.3946934617779601 0.466397887859792 0.5519923038040191 1.0 12.5857986961004 -10.62794605004764 4.98667794934076 1.0000153234604998 0.5552679349007873 0.6322307128103971 0.1017308650220033 154034718.77470276 4.094607515017106 27102.109130660578 0.026189966112865063 2.3553418565487654e-11 10.62794605004764 -0.4447473885597125 S(ph)PHQLLSPSSFSPSATPSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPHQLLSPSSFSPSATPSQK 20 0 E9PIQ6;A0A3B3ITS5;Q14181 E9PIQ6 POLA2 DNA polymerase alpha subunit B 1 S(0.997)PHQLLS(0.003)PSSFSPSATPSQK 106.5 7.2467e-05 10819000.0 23844.0 26923.0 43223.0 49058.0 54349.0 57026.0 49571.0 48780.0 49495.0 42299.0 True False 27880.318259533367 29595.737512091648 44253.60024414034 46309.439308181936 43699.70359756095 54035.4561714644 44875.276017039025 47499.57668668225 50218.770739659485 49967.47386130021 0.5579693369515456 0.5923000549165951 0.885648139167082 0.9267916852616513 0.8745629950968233 1.0814126069582004 0.8980897481750605 0.9506099271404364 1.0050292091822937 1.0 15.608701663064576 -5.296206985009134 2.3048616872809466 0.9597901929872404 0.5444832859211844 0.8823093236565094 0.05580009043354415 0.0973355874454212 0.972990954100301 0.015379853937321804 0.05099902000493931 5.0558364310691396e-06 5.296206985009134 -0.415306907066056 S(ph)PHQLLSPSSFSPSATPSQK ddPTM_PC-9_Lapatinib_30min_R1 1 SPHQLLSPSSFSPSATPSQK 20 0 E9PIQ6;A0A3B3ITS5;Q14181 E9PIQ6 POLA2 DNA polymerase alpha subunit B 1 S(0.979)PHQLLS(0.02)PSSFSPSATPSQK 96.045 0.00028773 12817000.0 30866.0 28241.0 42911.0 28474.0 45837.0 44873.0 30531.0 40565.0 47306.0 31630.0 True False 30425.84517986885 28175.609699621873 39383.02322125014 30568.072946479497 43140.957779009295 42953.88639407204 32111.745790669676 42449.797989813145 41977.90012573583 37097.20335567424 0.8201654687593866 0.75950764885117 1.0616170400679616 0.8239993902883768 1.1629167127610611 1.1578739772442168 0.8656109594783779 1.14428566441573 1.1315650865448612 1.0 15.17902281014275 -5.437092927145255 0.9818801187779714 1.0705486340962422 0.7512989105079214 0.41813394010017846 0.1162062547233519 0.8455555807963716 1.2481536536092084 0.04274193443227909 0.22987991879144087 3.655165726919552e-06 5.437092927145255 -0.3192497235883208 S(ph)PIALPVK ddPTM_PC-9_Lapatinib_30min_R1 2 SPIALPVK 8 0 Q8TF01;Q8TF01-2 Q8TF01 PNISR Arginine/serine-rich protein PNISR 1 S(1)PIALPVK;S(1)PIALPVK 81.95 0.017159 5982900.0 29757.0 60730.0 62544.0 53647.0 72843.0 66482.0 55577.0 66324.0 61348.0 55636.0 True False 29332.65972323454 60589.383416240074 57401.87374682176 57592.379341145774 68558.51795484811 63638.7198371114 58454.50511965048 69405.65516766602 54438.34221692055 65252.60846968988 0.44952470730514454 0.9285358062641144 0.879687036166304 0.8826065454210567 1.0506632541240684 0.9752670633339027 0.8958186728550913 1.0636456809217862 0.8342707440148909 1.0 15.993747954045267 -4.759750759357813 5.562797517988942 0.9476992714136618 0.4254562536950631 0.8101701688622712 0.07209132032795233 0.06111239201106782 6.1246165553662 0.01755553639102682 0.1229253895579605 1.7387984350343445e-05 4.759750759357813 -0.5222430177185987 down S(ph)PIALPVKQEPPQIDAVK ddPTM_PC-9_AZD4547_30min_R2 2 SPIALPVKQEPPQIDAVK 18 1 Q8TF01;Q8TF01-2 Q8TF01 PNISR Arginine/serine-rich protein PNISR 1 S(1)PIALPVKQEPPQIDAVK;S(1)PIALPVKQEPPQIDAVK 87.228 0.00078494 15772800.0 32451.0 26013.0 39071.0 62109.0 59730.0 54976.0 38442.0 52364.0 41336.0 50215.0 True False 42769.742977268565 34421.19353805968 38552.893011462125 47790.72962448444 51437.52051484893 51538.3420292302 41863.26352797823 44272.34700501337 43520.93657088349 48456.98813425646 0.8826331273163195 0.710345295144866 0.7956105919056765 0.986250517512024 1.061508824533925 1.0635894638444396 0.8639262393277632 0.913642153787004 0.8981354030981663 1.0 15.564417115770647 -5.756310312736877 23.374984541643194 0.9693260374336059 0.7876110851018734 0.5429656575161093 0.07276791441812859 44.20085569523568 201431.392334271 0.02159564835957246 0.03591498720709947 1.7526277641534518e-06 5.756310312736877 -0.18171495233173252 S(ph)PIALPVKQEPPQIDAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPIALPVKQEPPQIDAVK 18 1 Q8TF01;Q8TF01-2 Q8TF01 PNISR Arginine/serine-rich protein PNISR 1 S(1)PIALPVKQEPPQIDAVK;S(1)PIALPVKQEPPQIDAVK 81.016 0.001564 7704400.0 28317.0 18695.6 21203.0 30981.0 39709.0 34682.0 33867.0 32177.0 32735.0 22939.0 True False 33110.508813756365 20551.575613084 21708.55993282528 29245.235011757202 31928.30650344161 32863.21486582839 30658.872584153272 31332.38784434962 33213.68744646435 27097.65911497592 1.2218955398792126 0.7584262362251754 0.8011230726874015 1.07925318890717 1.1782680698716135 1.2127695136465146 1.1314214432348955 1.156276551838137 1.2257031984031534 1.0 14.725880606439162 -5.94388214209369 5.63141128854432 1.1582903765519723 0.9115324134286256 0.3729856016348323 0.1287983317134255 0.18349261069161182 12.17136686567632 0.03583715139486809 0.053439180125333 1.137936054574249e-06 5.94388214209369 -0.24675796312334675 S(ph)PIALPVKQEPPQIDAVK ddPTM_PC-9_Lapatinib_30min_R1 2 SPIALPVKQEPPQIDAVK 18 1 Q8TF01;Q8TF01-2 Q8TF01 PNISR Arginine/serine-rich protein PNISR 1 S(1)PIALPVKQEPPQIDAVK;S(1)PIALPVKQEPPQIDAVK 83.251 0.0010874 9944100.0 36713.0 37227.0 43772.0 31867.0 40464.0 41362.0 35440.0 29593.0 40016.0 31194.0 True False 36189.46588766034 37140.803168720064 40173.235124806255 34210.60548519567 38083.987075284866 39593.04367953132 37274.90979074823 30967.998814557886 35508.97669283909 36585.84133660773 0.9891658785347988 1.0151687596031047 1.0980541558465948 0.9350777304925498 1.0409487846649053 1.0821957957794617 1.018834292965979 0.8464476333791827 0.9705660822759014 1.0 15.158997815340475 -7.600452283187644 12.646624024511137 0.9314551483978473 1.0280024259992018 0.32977193227843726 0.05636864392991013 0.7539839335212847 120.32052112409859 0.025769090107858703 0.014872072646532689 2.5092718630905408e-08 7.600452283187644 0.09654727760135451 S(ph)PIGGMAGVK ddPTM_PC-9_AZD4547_30min_R2 2 SPIGGMAGVK 10 0 Q8IY33-4;Q8IY33-2;Q8IY33 Q8IY33-4 MICALL2 MICAL-like protein 2 1 S(1)PIGGMAGVK;S(1)PIGGMAGVK 81.771 0.013938999999999998 7026700.0 50767.0 54677.0 57254.0 52420.0 44759.0 59723.0 57941.0 72044.0 61474.0 55143.0 True False 66909.84998080152 72350.27098298882 56494.77455090095 40335.3788809267 38544.9854465783 55988.51136881034 63097.63675340999 60911.25520642403 64723.39013834164 53212.46035422294 1.2574094401085432 1.359649046508467 1.0616831880132662 0.7580062754554758 0.7243601440338094 1.0521691911275644 1.1857680763750396 1.1446803023380616 1.216320194696752 1.0 15.699476489681407 -5.337168897769289 5.308041323893323 1.0080648125004021 1.3076473309136716 0.35696753465971875 0.15655232441540382 0.24601087618565057 12.373103696279854 0.0477403608821225 0.103429869222814 4.600776139171337e-06 5.337168897769289 0.29958251841326944 S(ph)PIGGMAGVK ddPTM_PC-9_Lapatinib_30min_R1 1 SPIGGMAGVK 10 0 Q8IY33-4;Q8IY33-2;Q8IY33 Q8IY33-4 MICALL2 MICAL-like protein 2 1 S(1)PIGGMAGVK 68.22399999999999 0.036587 3337800.0 22425.0 30183.0 30934.0 25881.0 32656.0 33601.0 25785.0 27947.0 28209.0 28529.0 True False 22105.21538775866 30113.113117937977 28390.72592869317 27784.37507648508 30735.238284166222 32163.963557756677 27120.02113302603 29245.519645539473 25031.805366061 33460.199637497 0.6606420651174647 0.8999681246429826 0.848492424918985 0.8303708697944727 0.9185611149110701 0.9612603602553614 0.8105158195958317 0.8740390064130291 0.7481068743537692 1.0 15.030158432671312 -4.75689091689279 24.990778113743623 0.8724119868595737 0.6606417465704545 0.4624349083892926 0.0697760501804961 125.10233438029537 687269.1265074529 0.016788666455830558 0.13073846012210152 1.750286258307672e-05 4.75689091689279 -0.21177024028911917 S(ph)PIINESR ddPTM_PC-9_AZD4547_30min_R2 2 SPIINESR 8 0 Q13523 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 S(1)PIINESR;S(1)PIINESR 89.9 0.009878399999999999 17066300.0 8312.3 12916.5 14343.0 18519.7 17351.3 21764.0 19846.9 17082.9 12331.7 18796.1 True False 10955.438493419293 17091.506029075757 14152.802448450291 14250.269291512745 14942.37150023938 20403.09363948209 21613.23565146015 14443.130330989661 12983.528486335481 18138.054260087567 0.6040029617469235 0.9423009648110537 0.780282286374744 0.785655897108555 0.8238133642107233 1.12487774856748 1.1915961514692153 0.7962888479593694 0.7158170496217712 1.0 14.146732080185348 -6.550182352316328 23.926528236274006 0.9679065745890789 0.7917986402298117 0.2620950516130751 0.15059789612519084 212.5591411751118 186266.39060595003 0.05295201427744475 0.052953551350375744 2.817199792183484e-07 6.550182352316328 -0.1761079343592672 S(ph)PIINESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPIINESR 8 0 Q13523 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 S(1)PIINESR;S(1)PIINESR 73.84100000000001 0.028852 25125600.0 23167.9 25201.0 21294.0 30853.0 31970.0 25605.0 30644.0 28916.0 26373.0 20369.6 True False 27089.76788311706 27702.788732393183 21801.729717944712 29124.406436775607 25705.70799856526 24262.228724973644 27741.178476652567 28156.985639034516 26758.65523218586 24062.44723433511 1.1258110041468357 1.151287251151396 0.906047897191249 1.2103675969922751 1.068291506189169 1.0083026256096455 1.1528826725931771 1.1701630081439447 1.1120504482188946 1.0 14.554495756614365 S(ph)PIINESR ddPTM_PC-9_Lapatinib_30min_R1 2 SPIINESR 8 0 Q13523 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 S(1)PIINESR;S(1)PIINESR 112.85 0.0037234 38317000.0 6083.1 12542.400000000001 18365.5 9004.2 10473.2 12700.0 9729.7 12740.900000000001 15193.8 8465.3 True False 5996.353878496086 12513.358843402764 16855.55948288013 9666.398905130663 9857.18696710344 12156.85060514597 10233.45625821227 13332.888726942208 13482.514246192983 9928.515825696773 0.6039526938131529 1.2603453590733023 1.6976917576396393 0.9735995867692828 0.9928157581812257 1.2244378534082474 1.030713596862711 1.3428883995364453 1.357958680117911 1.0 13.277362355795429 -7.76801977796716 24.801638080678284 1.2628176211296556 1.134598466737482 0.03161498704932553 0.27638627677902367 583.0242449254172 2197379.041419529 0.14975536142854165 0.07460582521310541 1.706004695008502e-08 7.76801977796716 -0.12821915439217357 S(ph)PILEEK ddPTM_PC-9_AZD4547_30min_R2 4 SPILEEK 7 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;F5GXF5;Q12830-2;A0A0A0MR81 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 S(1)PILEEK;S(1)PILEEK;S(1)PILEEK;S(1)PILEEK 99.01299999999999 0.011978 125384000.0 669890.0 725080.0 754810.0 667620.0 633200.0 818680.0 782390.0 842190.0 733940.0 758240.0 True False 882901.0854224046 959447.9302877905 744800.7262159067 513710.5236261783 545291.1098275958 767487.8101806266 852021.1943097358 712048.8871009145 772734.5700317938 731694.2483902925 1.2066530348772906 1.3112689246888982 1.0179125062885872 0.7020835885430664 0.7452444938951227 1.048918741494933 1.164449763250373 0.9731508600312258 1.0560894413640518 1.0 19.480881392781725 -5.3550276095639555 5.01995769770084 0.9522883372279929 1.257348944451081 0.44006383660952886 0.13422883954140824 0.2091890370503753 8.439400880258273 0.04009948179257865 0.08702563988938446 4.415423761240113e-06 5.3550276095639555 0.30506060722308814 S(ph)PILEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPILEEK 7 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;F5GXF5;Q12830-2;A0A0A0MR81 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 S(1)PILEEK;S(1)PILEEK;S(1)PILEEK;S(1)PILEEK 109.44 0.009612299999999999 117882000.0 634460.0 767280.0 662430.0 642050.0 739740.0 597170.0 716060.0 486850.0 566540.0 557193.0 True False 741861.5468437979 843450.487623135 678224.8434797653 606078.0200541866 594793.2572680229 565853.3539422972 648229.6129745415 474070.7033602143 574824.5757116197 658207.6801626387 1.1270934223382032 1.2814351959775432 1.0304116222286872 0.920800589723336 0.9036559055662393 0.8596881668145815 0.9848405488285527 0.720244867460487 0.8733179405770295 1.0 19.32818333479137 -5.558577745512119 2.5136500626776335 0.8832140150755502 1.204821597325313 0.6938901362052912 0.0815312791193687 0.1451806024599289 1.8335582512288375 0.02273359417256673 0.05024449160789042 2.7632632075118645e-06 5.558577745512119 0.3216075822497627 S(ph)PILEEK ddPTM_PC-9_Lapatinib_30min_R1 4 SPILEEK 7 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;F5GXF5;Q12830-2;A0A0A0MR81 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 S(1)PILEEK;S(1)PILEEK;S(1)PILEEK;S(1)PILEEK 98.044 0.012289 141789000.0 726660.0 721350.0 700200.0 632660.0 722390.0 726680.0 702800.0 686520.0 678540.0 569380.0 True False 716297.6951468767 719679.7583946135 642632.2588501637 679187.9268918928 679900.4404733845 695601.5903738167 739187.5451731889 718418.2254644769 602115.6798570324 667796.5743488383 1.0726285858014941 1.0776930970278875 0.9623173935517533 1.0170581176672882 1.0181250796866523 1.0416369551642142 1.106905266613509 1.07580399939158 0.9016453557644396 1.0 19.34904916714509 -8.25466779138704 24.977242949103495 0.9508226759450739 1.0446747137754144 0.42473118538571675 0.04450802709399703 488.4035299352949 1801511.5191191551 0.03343465825505511 0.011991431366536362 5.563296525745757e-09 8.25466779138704 0.09385203783034057 S(ph)PILEEKDIPPLEFPK ddPTM_PC-9_AZD4547_30min_R2 2 SPILEEKDIPPLEFPK 16 1 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;F5GXF5;Q12830-2;A0A0A0MR81 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 S(1)PILEEKDIPPLEFPK;S(1)PILEEKDIPPLEFPK 93.684 0.0012840999999999998 81446000.0 74755.0 51157.0 86214.0 150639.0 124941.0 92494.0 67713.0 80392.0 67904.0 96356.0 True False 98525.53499940544 67692.49982034054 85070.7460287732 115911.5058993498 107595.09878864465 86710.33555827316 73739.3258225377 67969.26362438 71493.2668112365 92982.60576848374 1.0596125391960187 0.7280125057893868 0.914910324632005 1.246593434775924 1.1571529739287407 0.9325436176113645 0.7930443034274642 0.7309890173826257 0.7688886133095336 1.0 16.504673236430122 -7.105621801718757 4.130953030236769 0.8022643606077114 1.0141091584785944 0.2817500601219025 0.14649206083577848 0.3237233029688222 9.508773039963433 0.06332367863396708 0.04880099198917025 7.841121768636941e-08 7.105621801718757 0.21184479787088295 S(ph)PILEEKDIPPLEFPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPILEEKDIPPLEFPK 16 1 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;F5GXF5;Q12830-2;A0A0A0MR81 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 S(1)PILEEKDIPPLEFPK 86.213 0.0021421 5955800.0 10741.0 4354.0 6525.5 14452.0 11448.0 17112.0 10404.0 14922.0 12431.0 10362.0 True False 12559.239155579939 4786.236345416447 6681.092668096564 13642.301294016164 9204.846580155614 16214.616596045655 9418.457801562889 14530.313311165894 12612.779857858503 12240.548574453132 1.0260356453134736 0.3910148565894875 0.545816441759846 1.1145171485605299 0.7519962462602994 1.324664209076926 0.7694473613069809 1.1870638985487674 1.0304096896590274 1.0 13.579380595088878 -5.76067290857614 24.99999905468487 1.0236444924483556 0.6279615161231419 0.37145624620150675 0.22044162183478477 19.38908980512808 632366.150545026 0.05773665592418283 0.09292195517259003 1.7351103142227983e-06 5.76067290857614 -0.39568297632521376 S(ph)PILEEKDIPPLEFPK ddPTM_PC-9_Lapatinib_30min_R1 2 SPILEEKDIPPLEFPK 16 1 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;F5GXF5;Q12830-2;A0A0A0MR81 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 S(1)PILEEKDIPPLEFPK;S(1)PILEEKDIPPLEFPK 107.63 0.00041802 60173000.0 212524.0 93876.0 134608.0 113736.0 109799.0 110487.0 77179.0 75718.0 124929.0 73803.0 True False 209493.36878787167 93658.63588972417 123541.04984190612 122100.52485217356 103340.83869313968 105761.72856777669 81174.95098025269 79236.13470214904 110858.1804593086 86559.75021368384 2.420216882219628 1.0820113928068857 1.4272343616626573 1.4105923890809846 1.1938671084196704 1.22183495570043 0.9377909568807894 0.9153923677753746 1.2807128045730372 1.0 16.401408715521022 -4.758919184942344 24.993579612306625 1.172344354332508 2.420218529253371 0.8279669263206978 0.17183997327159778 29.055831724356658 288096.1401465445 0.04657111580036507 0.3074143347813795 1.742131025151608e-05 4.758919184942344 1.247874174920863 S(ph)PILLPK ddPTM_PC-9_AZD4547_30min_R2 4 SPILLPK 7 0 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 S(1)PILLPK;S(1)PILLPK;S(1)PILLPK;S(1)PILLPK 82.426 0.022498 351360000.0 664181.0 707677.0 773036.0 716110.0 745553.0 769486.0 789069.0 949959.0 787774.0 757182.0 True False 875376.7421769822 936419.7508720035 762785.0375472512 551021.9032892099 642045.835131546 721369.9187773608 859294.6123707974 803164.6644361685 829414.1253675034 730673.2886482637 1.1980412528784488 1.2815847594543495 1.0439481631501732 0.7541289819265098 0.8787044019623637 0.9872674011552907 1.176031238202893 1.099211750195512 1.1351367817234828 1.0 19.478866941887844 -5.333610684316183 5.518265298601559 1.0025349362954166 1.2391148554907707 0.3817106386968858 0.1177275619431054 0.23109169871044186 12.87283313763384 0.03556583741832212 0.07672878838748476 4.638625548791321e-06 5.333610684316183 0.23657991919535415 S(ph)PILLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPILLPK 7 0 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 S(1)PILLPK;S(1)PILLPK;S(1)PILLPK;S(1)PILLPK 90.601 0.015819 184452200.0 217186.0 291273.0 279817.0 240774.0 289095.0 205445.0 253163.0 187147.0 195364.0 163063.0 True False 253951.30018096883 320188.65848380385 286488.8984918812 227284.2133798398 232448.91003582196 194671.1025347472 229181.56789860298 182234.58954863754 198220.82890762348 192625.03109400198 1.3183712352370203 1.6622380625472821 1.4872880064692795 1.1799308329192377 1.2067430111011155 1.0106220434027948 1.1897808223416262 0.9460587158047291 1.0290502110854467 1.0 17.55543566406024 -5.970090856689775 1.5773543814058932 1.050726250022115 1.5197153071944818 0.7499214925524481 0.10958982335775186 0.18056306127047397 0.9098358449799493 0.03639217604451987 0.06418591815958624 1.0712951612101941e-06 5.970090856689775 0.4689890571723667 S(ph)PILLPK ddPTM_PC-9_Lapatinib_30min_R1 1 SPILLPK 7 0 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 S(1)PILLPK 71.029 0.042466000000000004 116300000.0 234920.0 295530.0 269750.0 243630.0 285270.0 252900.0 317310.0 267630.0 321660.0 245210.0 True False 231569.9977209487 294845.71844230854 247572.1962651123 261547.3629258553 268490.9794623992 242084.05653869428 333738.7591902463 280065.06683134934 285431.2635700376 287594.2217782125 0.8051969761045176 1.0252143336512798 0.8608385618263065 0.9094319117703134 0.9335757088661351 0.8417556341774667 1.160450154828283 0.9738202148140879 0.9924791319004909 1.0 18.13367516448502 -7.2398349971107345 24.99961355007596 1.029505754434135 0.9025954508065327 0.45092241157412993 0.07311797451973608 766.0379805965113 886425.6274978576 0.026678561842582913 0.02064489861480852 5.7565860760741687e-08 7.2398349971107345 -0.12691030362760236 S(ph)PISDNSGCDAPGNSNPSLSVPSSAESEK ddPTM_PC-9_AZD4547_30min_R2 1 SPISDNSGCDAPGNSNPSLSVPSSAESEK 29 0 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 S(0.947)PIS(0.049)DNS(0.004)GCDAPGNSNPSLSVPSSAESEK 101.58 3.5686e-11 11706000.0 57142.0 64575.0 66444.0 56098.0 69027.0 72738.0 72861.0 77604.0 70218.0 61813.0 True False 75311.96737256428 85447.6059170492 65562.90914626168 43165.47280546023 59443.792542750314 68189.68136136033 79345.48784954003 65612.08496251363 73929.58012711188 59648.94568441292 1.2625867315580117 1.4325082352524767 1.0991461524422912 0.723658604694164 0.9965606577063739 1.1431833468127706 1.3302077168192779 1.0999705729863212 1.2394113471553057 1.0 15.864209017565317 -5.304014211607316 8.83610471968837 1.0779526404924071 1.3473273792454628 0.31795526801081153 0.15732951450678978 0.4555220286080156 91.23297264485043 0.04542300081017226 0.09550984770303565 4.965760715095857e-06 5.304014211607316 0.2693747387530556 S(ph)PISDNSGCDAPGNSNPSLSVPSSAESEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPISDNSGCDAPGNSNPSLSVPSSAESEK 29 0 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 S(0.98)PIS(0.02)DNSGCDAPGNSNPSLSVPSSAESEK;S(0.952)PIS(0.046)DNS(0.001)GCDAPGNS(0.001)NPSLSVPSSAESEK;S(0.811)PIS(0.176)DNS(0.013)GCDAPGNSNPSLSVPSSAESEK 132.3 7.2533e-12 20097000.0 146520.0 180082.0 165792.0 169523.0 177333.0 149210.0 179088.0 133876.0 134901.0 131989.0 True False 171322.94209808877 197959.35083952293 169745.11004966134 160025.17591098163 142585.8716455922 141385.164930807 162123.48815516126 130361.89685334737 136873.67191738158 155917.56087565102 1.098804657640354 1.2696411470764446 1.0886850018455472 1.0263447876702392 0.9144952681712919 0.9067943606658004 1.0398026190549483 0.8360950243270862 0.8778592427221362 1.0 17.250423901262963 -5.806335620642616 1.866096676879404 0.9255640681245256 1.1839888473108704 0.6841313686973004 0.0688450707295599 0.18389442426241437 1.3076180958980181 0.021249217287971113 0.041268652068633595 1.5619401164652261e-06 5.806335620642616 0.25842477918634477 S(ph)PISDNSGCDAPGNSNPSLSVPSSAESEK ddPTM_PC-9_Lapatinib_30min_R1 2 SPISDNSGCDAPGNSNPSLSVPSSAESEK 29 0 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 S(0.968)PIS(0.026)DNS(0.005)GCDAPGNS(0.001)NPSLSVPSSAESEK;S(0.977)PIS(0.021)DNS(0.002)GCDAPGNSNPSLSVPSSAESEK 101.37 3.7241e-11 16531000.0 51311.0 67840.0 69825.0 62660.6 84443.0 76742.0 71721.5 76352.8 71133.6 64694.0 True False 50579.29573071499 67682.9206480773 64084.258032294514 67268.86955363402 79476.22876132566 73459.92355433943 75434.88833400529 79900.42982760015 63121.784897984195 75876.2717006636 0.6666022802260676 0.8920169524814088 0.8445889155586179 0.8865600278702902 1.0474450968659097 0.9681541001927876 0.9941828537859689 1.053035791516116 0.8319041445131015 1.0 16.21136117096213 -3.9218741527250516 0.6476308440627982 0.98228253565103 2.743758091838393e-19 0.6261738523766522 0.06909186841071692 5.825877447492605 0.8108101767540985 0.029594978685646568 5.456712057128673 0.00011970873659183271 3.9218741527250516 -0.98228253565103 S(ph)PISFLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPISFLSK 8 0 Q7RTP6;A0A5F9ZHV5;J3KSK6;Q7RTP6-2;Q7RTP6-4;Q7RTP6-3;Q7RTP6-5 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 S(1)PISFLSK 81.95 0.017159 2250600.0 20787.0 18434.0 22439.0 20429.0 22591.0 14811.0 25920.0 13807.0 17798.0 12124.0 True False 24305.828538035592 20264.005693938172 22974.03086038138 19284.429361711613 18164.455720850423 14034.28508672464 23464.669955450823 13444.580879725736 18058.262079492066 14321.9852264688 1.6970991209455666 1.4148880461409625 1.6041093812834362 1.3464913597363306 1.2682917510123013 0.9799119929817792 1.6383671386621186 0.9387372397842226 1.2608770218613383 1.0 13.805943863623126 -1.5228787456526531 0.1886862648253725 1.005378931428666 3.9642371455056002 0.4622069459627036 0.194483128638556 49.396285621036384 0.5746875035339366 0.3880523705607009 42.46710938995007 0.029999999974281353 1.5228787456526531 2.958858214076934 S(ph)PISPELHSAPLTPVAR ddPTM_PC-9_AZD4547_30min_R2 2 SPISPELHSAPLTPVAR 17 0 A0A1W2PRB5;A0A0J9YVS1;A0A3B3IT55;A0A0G2JNB1;A0A0G2JNT7;Q7Z3B3;A0A0G2JQF5;A0A0G2JQF4;Q7Z3B3-4;Q7Z3B3-2 A0A1W2PRB5 KANSL1 KAT8 regulatory NSL complex subunit 1 1 S(1)PISPELHSAPLTPVAR;S(0.976)PIS(0.024)PELHSAPLTPVAR 159.4 1.651e-05 16737100.0 19538.2 17568.4 28494.0 31724.0 28781.0 23405.3 21573.9 30579.0 19337.5 24572.9 True False 25750.94118019379 23247.041731213147 28116.150942351156 24410.52193091413 24785.254946222445 21941.76289102049 23493.935305817842 25853.71818551494 20359.64077171132 23712.61025040866 1.0859597871453228 0.9803662053953976 1.1857045953794398 1.0294320900624359 1.0452352012067208 0.9253204374934788 0.9907781158513729 1.0902940634749134 0.8585997305530902 1.0 14.53336686092887 -6.586283444799896 6.42403863424882 0.979712853278796 1.0681026546996752 0.28619280056282626 0.07331800045056883 0.29606367848631343 22.988760922708078 0.02367323490447904 0.023713898167536007 2.592486808374869e-07 6.586283444799896 0.08838980142087927 S(ph)PISPELHSAPLTPVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPISPELHSAPLTPVAR 17 0 A0A1W2PRB5;A0A0J9YVS1;A0A3B3IT55;A0A0G2JNB1;A0A0G2JNT7;Q7Z3B3;A0A0G2JQF5;A0A0G2JQF4;Q7Z3B3-4;Q7Z3B3-2 A0A1W2PRB5 KANSL1 KAT8 regulatory NSL complex subunit 1 1 S(0.838)PIS(0.162)PELHSAPLTPVAR;S(0.981)PIS(0.019)PELHSAPLTPVAR 98.443 0.00076812 12970700.0 26684.1 35631.0 35025.0 31473.0 45514.0 31656.0 31698.0 28176.0 31264.0 20274.1 True False 31201.191095001457 39168.210202924536 35860.128833052186 29709.669846842706 36595.85842498279 29995.903632796944 28695.335966353377 27436.409854939702 31721.176854322923 23949.633840312716 1.3027836376555666 1.6354408783066852 1.4973142834731519 1.2405062242260476 1.5280341515444626 1.2524577132493346 1.1981534313920306 1.1455878631746739 1.3244952747849081 1.0 14.5477159786924 -7.386347114424616 0.31423737573983207 1.000693735556212 1.5509100651766166 0.5207537444709746 0.12623738838540602 1.284590049596107 0.36079530846926167 0.18637688500617092 0.25496330243785414 4.108212366627934e-08 7.386347114424616 0.5502163296204046 S(ph)PISPELHSAPLTPVAR ddPTM_PC-9_Lapatinib_30min_R1 2 SPISPELHSAPLTPVAR 17 0 A0A1W2PRB5;A0A0J9YVS1;A0A3B3IT55;A0A0G2JNB1;A0A0G2JNT7;Q7Z3B3;A0A0G2JQF5;A0A0G2JQF4;Q7Z3B3-4;Q7Z3B3-2 A0A1W2PRB5 KANSL1 KAT8 regulatory NSL complex subunit 1 1 S(0.993)PIS(0.007)PELHSAPLTPVAR;S(0.977)PIS(0.023)PELHSAPLTPVAR 135.18 6.6985e-07 6652700.0 26806.0 28059.0 34054.0 21083.0 34746.0 31344.0 25701.0 27855.0 30188.0 21666.8 True False 26423.741524381643 27994.031109439806 31254.211572241427 22633.514150826275 32702.308593264308 30003.49018643271 27031.67202404119 29149.244989676958 26787.909546267158 25411.877510803744 1.0398185459987248 1.1016120748078637 1.2299056438845906 0.8906667420069115 1.2868906903616653 1.1806876596849982 1.0637416307610013 1.1470716784812256 1.0541491684303295 1.0 14.63321534980339 -10.71674682405394 6.61148487387395 0.9999994653192902 1.114241400683535 0.08950209195871095 0.10513045190166352 7.941869022102733e-07 9.674968224759451e-08 0.09756043739081859 0.023661771126163914 1.9197875722712083e-11 10.71674682405394 0.11424193536424487 S(ph)PISVPGGSALISNLGK ddPTM_PC-9_AZD4547_30min_R2 2 SPISVPGGSALISNLGK 17 0 P51610;A6NEM2;P51610-2;P51610-4 P51610 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 S(1)PISVPGGSALISNLGK;S(0.997)PIS(0.003)VPGGSALISNLGK 208.85 1.613e-17 90233000.0 52741.0 67977.0 74900.0 75518.0 79658.0 100478.0 93669.0 121603.0 95505.0 80172.0 True False 69511.54091905098 89949.23588731328 73906.77706120937 58108.49184146935 68598.86169716777 94195.0947761385 102005.35953910297 102812.05050894986 100553.1993226783 77365.20268245747 0.8984858632679922 1.1626575355396727 0.95529740113985 0.7510933834164882 0.8866888383751695 1.2175382666902417 1.3184914664772491 1.3289185181991703 1.299721267911558 1.0 16.239397196491865 -6.818759797011907 5.665667459029108 1.2629868681608942 0.9351675183217857 0.5710855486932349 0.12987758871617322 0.14508172068648562 9.498838674343775 0.04776680334283574 0.04256742661345564 1.5178896616197053e-07 6.818759797011907 -0.32781934983910854 S(ph)PISVPGGSALISNLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPISVPGGSALISNLGK 17 0 P51610;A6NEM2;P51610-2;P51610-4 P51610 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 S(1)PISVPGGSALISNLGK;S(1)PISVPGGSALISNLGK 224.36 6.6963e-29 60441000.0 86366.0 155536.0 166288.0 132768.0 164224.0 113192.0 145878.0 100439.0 105429.0 109056.0 True False 100986.05799374504 170976.58617838583 170252.9365707521 125329.4393996637 132045.48609184797 107256.01225687236 132059.37977473956 97802.58267391703 106970.69967292793 128826.98951317924 0.7838889845626174 1.327179862111849 1.3215626416026347 0.9728507968188006 1.0249830923693164 0.832558555176824 1.0250909399790766 0.759177739412374 0.830343859444023 1.0 16.97507534706464 -6.248826347547878 1.8814504951244535 0.8871101940297026 1.1529003369245405 0.2675987289739884 0.1651640250354052 0.4148723220463113 2.889423080800515 0.05722368360761059 0.07589801321703549 5.638630711507617e-07 6.248826347547878 0.26579014289483793 S(ph)PISVPGGSALISNLGK ddPTM_PC-9_Lapatinib_30min_R1 2 SPISVPGGSALISNLGK 17 0 P51610;A6NEM2;P51610-2;P51610-4 P51610 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 S(0.981)PIS(0.019)VPGGSALISNLGK;S(1)PISVPGGSALISNLGK 220.97 6.515e-23 67148000.0 75659.0 102734.0 102276.0 99135.0 116186.0 115190.0 129860.0 119682.0 117927.0 95945.0 True False 74580.08878583864 102496.12573495801 93867.2620767769 106425.71860466564 109352.16791046469 110263.59222100512 136583.51539013995 125242.86264062162 104644.81943363733 112528.96541132372 0.6627634806134429 0.9108421583750195 0.8341608912306866 0.9457628817225053 0.9717690686193818 0.9798685326747825 1.213763184357826 1.1129833299615364 0.9299367416303197 1.0 16.779936879226497 -4.796923308119192 0.5222853389815538 1.0678921682367637 0.47392879452753794 0.6237247748355043 0.08620477147141803 2.887287458993822 0.6104722928840733 0.05431321662981742 1.0543898841413153 1.596160987751788e-05 4.796923308119192 -0.5939633737092258 S(ph)PKPAAPAAPPFSSSSGVLGTGLCELDR ddPTM_PC-9_AZD4547_30min_R2 1 SPKPAAPAAPPFSSSSGVLGTGLCELDR 28 1 H3BS04;H3BN49;H3BSN4;H3BQC4;O43294-2;O43294 H3BS04 TGFB1I1 Transforming growth factor beta-1-induced transcript 1 protein 1 S(0.688)PKPAAPAAPPFS(0.055)S(0.153)S(0.068)S(0.031)GVLGT(0.004)GLCELDR 45.47 0.014816 10198000.0 30938.0 26973.0 37084.0 43824.0 43993.0 37151.0 40151.0 45054.0 35024.0 37713.0 True False 40775.64044962356 35691.49476423649 36592.24192974484 33721.05387405056 37885.33132445586 34827.942097059284 43724.36121720651 38091.93953792439 36875.29713708686 36392.67934894383 1.1204352407981453 0.9807328122784209 1.0054835913258144 0.9265889315464538 1.041015171243646 0.9570040656561344 1.2014603486037492 1.0466923628427451 1.0132613975331564 1.0 15.151360650600855 S(ph)PLAIR ddPTM_PC-9_AZD4547_30min_R2 1 SPLAIR 6 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(1)PLAIR 91.9 0.035923000000000004 6612100.0 12049.0 12832.0 14524.0 13053.0 13263.0 15994.0 16216.0 16472.0 10895.0 15192.0 True False 15880.331365230932 16979.693056563316 14331.402270186985 10043.832516839673 11421.66138604455 14993.892651620867 17659.192585445464 13926.630888904216 11470.887457416666 14660.132704084917 1.0832324431010107 1.1582223298587244 0.9775765717450611 0.6851119781501738 0.7790967255611544 1.0227665024780404 1.2045724920706131 0.9499662226811687 0.7824545445090277 1.0 13.839610542411263 -5.394667802528548 5.110891501103601 0.9199728361274483 1.1177672972800576 0.2445517810051825 0.14011369309511634 0.3443769042631719 12.713790527438027 0.04148311932365716 0.08893242284414267 4.0302519564173196e-06 5.394667802528548 0.19779446115260935 S(ph)PLAQMEEER ddPTM_PC-9_AZD4547_30min_R2 2 SPLAQMEEER 10 0 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181;A0A0U1RRM2 G3V1Q4 SEPT7 Septin-7 1 S(1)PLAQMEEER;S(1)PLAQMEEER 74.78 0.0236 13132700.0 19411.4 20778.2 18467.7 26312.1 20188.9 23041.2 17980.9 23828.4 20490.6 19272.7 True False 25583.821417797648 27494.34681015305 18222.80623141917 20246.251862892615 17386.019720780743 21600.430121578487 19581.16526638115 20146.268302159133 21573.691283611006 18597.968639153325 1.3756245057827108 1.4783521439148277 0.979827775010635 1.0886270568426084 0.9348343390674867 1.1614402917157436 1.052865807352635 1.083251009454132 1.1600025627633896 1.0 14.182857431298723 -5.2586197018418 24.999902443032997 1.060841604836987 1.4269883557778267 0.8054514656418867 0.07260172270046808 92.47819512691731 819921.6307775629 0.0180568102007024 0.04355657034375965 5.5129023279869745e-06 5.2586197018418 0.3661467509408396 S(ph)PLAQMEEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPLAQMEEER 10 0 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181;A0A0U1RRM2 G3V1Q4 SEPT7 Septin-7 1 S(1)PLAQMEEER;S(1)PLAQMEEER;S(1)PLAQMEEER 92.11200000000001 0.006728499999999999 23973000.0 56712.0 89590.0 67482.0 65047.0 77843.0 51197.0 68257.0 52931.0 56835.0 46914.0 True False 66312.22148694252 98483.9031203167 69091.02680691026 61402.627475219335 62590.22295065113 48512.139192832474 61791.20282211449 51541.61733503031 57666.104353743736 55419.13682898031 1.1965581797417295 1.7770739270846339 1.2466998001091298 1.1079679509391074 1.129397290033591 0.8753680040621643 1.114979524361737 0.9300328421585532 1.040544975135528 1.0 15.758096620100872 -5.626513506033947 2.7262173774160567 1.0213880256772174 1.4927304263306078 0.5876703575719192 0.15273821720179856 0.16275485614193366 2.4274904009546763 0.04078772137550592 0.08166431642579816 2.3631239077113767e-06 5.626513506033947 0.4713424006533904 S(ph)PLAQMEEER ddPTM_PC-9_Lapatinib_30min_R1 2 SPLAQMEEER 10 0 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181;A0A0U1RRM2 G3V1Q4 SEPT7 Septin-7 1 S(1)PLAQMEEER;S(1)PLAQMEEER 117.2 0.00097676 6422400.0 3192.02 4218.1 4941.4 5347.2 2903.9 1009.0 1477.8 2916.14 4463.0 2779.3 True False 3146.5012094552244 4208.333248609294 4535.137166355609 5740.450925736292 2733.098311287063 965.8474220938808 1554.313253069067 3051.6345102924624 3960.329942526508 3259.6983018155356 0.9652737517771922 1.291019247476186 1.3912751262378176 1.7610374931137236 0.8384513099770077 0.2962996365510079 0.4768273346657174 0.9361708439682319 1.2149375726952232 1.0 11.67052272807046 -6.424355257618291 7.756061633875832 0.7406444012360313 1.348377690899929 0.44593801503427655 0.3033194385520817 0.27339532282546747 19.164660171776376 0.10156250242544025 0.11505047909426099 3.763957771715317e-07 6.424355257618291 0.6077332896638977 S(ph)PLAQMEEERR ddPTM_PC-9_AZD4547_30min_R2 3 SPLAQMEEERR 11 1 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181;A0A0U1RRM2 G3V1Q4 SEPT7 Septin-7 1 S(1)PLAQMEEERR;S(1)PLAQMEEERR;S(1)PLAQMEEERR 99.834 0.002016 24023200.0 22834.9 14767.9 31081.6 43469.0 41517.0 29580.1 28655.4 36351.8 29882.7 27711.5 True False 30095.92320457399 19541.33487297549 30669.43767564332 33447.89363935524 35753.08118558486 27730.451670889706 31205.675087134587 30734.46459126204 31462.238515258825 26741.328819724124 1.1254460616921755 0.7307540700281883 1.1468928071002165 1.250793999985686 1.336997178659789 1.0369885452526957 1.1669455657011931 1.1493245080847523 1.176539831934328 1.0 14.706783536603528 -5.418408640385203 9.331434198178536 1.1707628517404742 0.9287443478045608 0.3446275197665776 0.1262957517976375 0.3532684756547518 29.18992981962592 0.031539839037399785 0.06575343490360472 3.81585057323923e-06 5.418408640385203 -0.2420185039359134 S(ph)PLAQMEEERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPLAQMEEERR 11 1 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181;A0A0U1RRM2 G3V1Q4 SEPT7 Septin-7 1 S(1)PLAQMEEERR;S(1)PLAQMEEERR;S(1)PLAQMEEERR 53.001000000000005 0.035979000000000004 35596100.0 57343.0 61455.0 72407.0 65143.0 70936.0 76111.0 67285.0 54605.0 78340.0 58994.0 True False 67050.03732412444 67555.84625805414 74133.45748507664 61493.24890645553 57036.600018336714 72119.60517424207 60911.277698785045 53171.676608779926 79485.5742952809 69689.14520375285 0.9621302876952738 0.9693883611362788 1.0637733791730373 0.8823935022687585 0.8184430997334894 1.0348757322734148 0.8740425430774963 0.7629836246853056 1.140573242258688 1.0 16.088646338652225 -5.777064455821356 24.991393732966234 0.9179283444506352 0.995526472041081 0.0701969107168191 0.10655197471429982 546.8673580433453 874680.9035546805 0.02923277710009915 0.043529348436628305 1.6708426177784333e-06 5.777064455821356 0.07759812759044582 S(ph)PLAQMEEERR ddPTM_PC-9_Lapatinib_30min_R1 2 SPLAQMEEERR 11 1 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181;A0A0U1RRM2 G3V1Q4 SEPT7 Septin-7 1 S(1)PLAQMEEERR;S(1)PLAQMEEERR 153.32 0.00018907 43436000.0 14440.7 11468.5 14634.7 11456.8 14792.0 13791.4 11055.3 12330.900000000001 12340.8 11440.7 True False 14234.772969899946 11441.945392872536 13431.491457575661 12299.371290764419 13921.963642190925 13201.573971323633 11627.689340001662 12903.83863016362 10950.84914961487 13418.209751225486 1.060854855738105 0.8527177324700519 1.000989827003484 0.9166179034905246 1.0375425559970421 0.9838550906627415 0.8665604097401819 0.9616661886646325 0.8161184951379024 1.0 13.711904580497539 -7.244062419274767 24.393771805798387 0.907891786258191 0.9711637268382323 0.15835619808586343 0.07211951650653474 1104.4315037789022 1550402.2692585385 0.0259430898241548 0.02004291865183119 5.700823309150721e-08 7.244062419274767 0.06327194058004126 S(ph)PLDPDSGLLSCTLPNGFGGQSGPEGER ddPTM_PC-9_AZD4547_30min_R2 1 SPLDPDSGLLSCTLPNGFGGQSGPEGER 28 0 Q9H4L4;A0A087X0R7 Q9H4L4 SENP3;SENP3-EIF4A1 Sentrin-specific protease 3 1 S(0.992)PLDPDS(0.008)GLLSCTLPNGFGGQSGPEGER 108.86 2.6414e-05 0.0 3755.8 4775.0 6689.5 6721.0 6367.6 6245.5 4860.8 5788.3 4878.5 4399.9 True False 4950.066274506958 6318.42536978568 6600.792859158348 5171.577288414883 5483.568652776693 5854.967897692763 5293.401783382667 4893.851236901666 5136.3675503448585 4245.8608402253285 1.1658569276717643 1.488137649242965 1.554641828253618 1.218027976663603 1.2915092743561702 1.378982523926064 1.2467205079433894 1.1526169653365155 1.2097352559657304 1.0 12.051841371777527 -8.142436682748007 0.4825042952209062 0.9981080155716792 1.3887595025622892 0.48383763412476155 0.1125324281286383 0.7901799664480043 0.4761907919390111 0.12803757139940644 0.07586484197512688 7.2038277060761305e-09 8.142436682748007 0.39065148699061003 S(ph)PLDPDSGLLSCTLPNGFGGQSGPEGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPLDPDSGLLSCTLPNGFGGQSGPEGER 28 0 Q9H4L4;A0A087X0R7 Q9H4L4 SENP3;SENP3-EIF4A1 Sentrin-specific protease 3 1 S(0.992)PLDPDS(0.008)GLLSCTLPNGFGGQSGPEGER 84.948 2.5644e-05 0.0 3066.3 5140.4 3784.3 3964.0 6491.5 3596.6 4147.4 3218.4 3333.4 2697.8 True False 3585.364027814428 5650.704940279904 3874.5320640376717 3741.909931461396 5219.537174622662 3407.9879645475567 3754.5282474242526 3133.920410176675 3382.144668826769 3186.8897842269516 1.125035464219587 1.7731096218787508 1.215772218799064 1.1741573084771981 1.6378154024830114 1.0693774166320085 1.178116753835274 0.9833789752276841 1.0612681635763506 1.0 11.637933410304761 -6.832529996265065 13.528975372294683 1.0646489803021548 1.3855601087324516 0.413118071716557 0.1946560157430187 1.0605789997622286 199.79216817911785 0.06678890209903554 0.058906794092942805 1.4705168448383893e-07 6.832529996265065 0.3209111284302968 S(ph)PLDPDSGLLSCTLPNGFGGQSGPEGER ddPTM_PC-9_Lapatinib_30min_R1 1 SPLDPDSGLLSCTLPNGFGGQSGPEGER 28 0 Q9H4L4;A0A087X0R7 Q9H4L4 SENP3;SENP3-EIF4A1 Sentrin-specific protease 3 1 S(0.977)PLDPDS(0.023)GLLSCTLPNGFGGQSGPEGER 97.999 5.7978999999999995e-05 0.0 2246.2 2966.2 3044.4 2364.1 1981.4 3067.3 2755.1 4157.4 2497.2 1214.2 True False 2214.1687760973687 2959.3319461427836 2794.101183723845 2537.9638004064122 1864.8579475822817 2936.11872922553 2897.7455971921668 4350.567981334876 2215.939039318217 1424.0728521801984 1.5548142587702343 2.0780762315721173 1.96204932875884 1.7821867726225462 1.3095242597506573 2.061775649139333 2.0348296035247317 3.0550178487528434 1.5560573575471952 1.0 10.475807237701385 -4.746041935813169 23.81736679200396 1.928872932409413 1.5548124239990095 0.0214994144755819 0.5222413908961603 1815.9450990011076 2808685.138726203 0.12873774521618078 2.837464921017558 1.794560334323504e-05 4.746041935813169 -0.3740605084104034 S(ph)PLELEPEAK ddPTM_PC-9_AZD4547_30min_R2 2 SPLELEPEAK 10 0 A0A087WTQ7;A0A087WV56;A0A087WW71;A0A087X0X5;Q92466-3;Q92466-2;Q92466-5;Q92466-4;Q92466 A0A087WTQ7 DDB2 DNA damage-binding protein 2 1 S(1)PLELEPEAK;S(1)PLELEPEAK 124.12 0.00042319 16394700.0 83090.0 109299.0 98053.0 83649.0 98162.0 101331.0 103273.0 123333.0 109662.0 89540.0 True False 109510.89162063545 144627.76429156144 96752.75315330783 64365.01541416698 84533.90069945775 94994.75655129371 112464.0969336895 104274.71876039481 115458.50944058989 86405.23185385481 1.2674104249365523 1.6738311001373598 1.1197557263309557 0.7449203483769767 0.9783423860540966 1.0994097754632168 1.3015889723426757 1.2068102419627127 1.3362444259842456 1.0 16.39883105005267 -5.3383475149457835 8.420715516268293 1.095361383269185 1.4696948193257158 0.39368002110756395 0.1848236170892214 0.32808168407347055 33.18265628540409 0.052140188296340095 0.10900655997052168 4.588307174869191e-06 5.3383475149457835 0.3743334360565307 S(ph)PLELEPEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPLELEPEAK 10 0 A0A087WTQ7;A0A087WV56;A0A087WW71;A0A087X0X5;Q92466-3;Q92466-2;Q92466-5;Q92466-4;Q92466 A0A087WTQ7 DDB2 DNA damage-binding protein 2 1 S(1)PLELEPEAK;S(1)PLELEPEAK 119.03 0.0008238999999999999 14948700.0 81131.0 124351.0 101056.0 93853.0 114681.0 77794.0 87658.0 61402.0 71157.0 68693.0 True False 94864.87588970833 136695.74547287117 103465.5582970141 88594.72068553147 92210.08129444659 73714.34569148991 79354.39965103804 59790.26256079673 72197.53650918174 81146.49712651139 1.1690569432936744 1.684555098660091 1.2750465141545937 1.0917873700377718 1.1363408718762873 0.9084106930280135 0.9779152823728253 0.7368187744146338 0.8897184606332695 1.0 16.308241198447355 -6.100728729105486 0.9824138339987456 0.8791307708337189 1.4433019799905917 0.650233521590768 0.1466094634187105 0.32566390286155494 0.650196053220859 0.06294242050562215 0.11974707682319105 7.9299650071502e-07 6.100728729105486 0.5641712091568728 S(ph)PLELEPEAK ddPTM_PC-9_Lapatinib_30min_R1 2 SPLELEPEAK 10 0 A0A087WTQ7;A0A087WV56;A0A087WW71;A0A087X0X5;Q92466-3;Q92466-2;Q92466-5;Q92466-4;Q92466 A0A087WTQ7 DDB2 DNA damage-binding protein 2 1 S(1)PLELEPEAK;S(1)PLELEPEAK 137.4 0.00011719 13311000.0 65280.0 83136.0 81437.0 81219.0 97979.0 85083.0 85184.0 95724.0 86796.0 80561.0 True False 64349.095229114195 82943.50369986048 74741.56421591071 87192.11619864129 92216.0678541256 81444.19842816015 89594.41071148695 100171.68649764282 77020.12047760039 94485.86150921504 0.6810447002469078 0.8778403707709342 0.7910343729958084 0.9228059606583319 0.9759774254175788 0.8619723324448604 0.9482308705281686 1.0601764634158863 0.8151496874491507 1.0 16.527810845850695 -3.5937373834535866 0.5153796170438906 0.9538031892884599 2.620721887099491e-15 0.5188901433094404 0.07366583565995644 10.911618269640991 0.863425982194766 0.03939850023413607 8.208149848985064 0.00025483707787868744 3.5937373834535866 -0.9538031892884572 S(ph)PLGFYVHLK ddPTM_PC-9_AZD4547_30min_R2 2 SPLGFYVHLK 10 0 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 1 S(1)PLGFYVHLK;S(1)PLGFYVHLK 118.77 0.00047933 7320900.0 75857.0 71830.0 87019.0 89042.0 92610.0 99636.0 86979.0 97857.0 78345.0 93093.0 True False 99977.94807638158 95047.6427877918 85865.07120279547 68514.74258518648 79752.70006496161 93405.74516924459 94719.96249935024 82735.44918015422 82486.15675551254 89833.84240530373 1.1129207590309969 1.0580382653450906 0.9558209790848939 0.7626829794952801 0.8877801275063023 1.0397612154651639 1.0543906390200006 0.9209830834895867 0.9182080443955563 1.0 16.454971422205787 -5.185541444257769 3.4326169218150775 0.9382542698814079 1.0995722281104192 0.3531779336562072 0.07883350175410471 0.2954513495229707 6.675513031592073 0.02313166715680976 0.07286045682852796 6.523167881346974e-06 5.185541444257769 0.1613179582290113 S(ph)PLGFYVHLK ddPTM_PC-9_Lapatinib_30min_R1 1 SPLGFYVHLK 10 0 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 1 S(1)PLGFYVHLK 96.334 0.0031571999999999998 3487900.0 18766.0 27787.0 25383.0 29885.0 24082.0 25187.0 26078.0 23667.0 26242.0 23030.0 True False 18498.393398737073 27722.660908728187 23296.107721213488 32082.84259343752 22665.544107033653 24109.8107237647 27428.191239366013 24766.655220631284 23286.34961948928 27010.70481445394 0.6848541541514397 1.0263582938381255 0.8624768543154527 1.1877825037823293 0.8391319020636918 0.8926020586794566 1.0154563321386811 0.9169199911946828 0.862115586374048 1.0 14.721243665418202 -4.751830622114246 24.988142226753727 0.9538406312827429 0.6848536158655043 0.39558195361088977 0.10047239926912385 398.7725081879691 1036958.5888804984 0.02407343689281901 0.30579474713242527 1.770799447831875e-05 4.751830622114246 -0.2689870154172386 S(ph)PLGGGGGSGASSQAACLK ddPTM_PC-9_AZD4547_30min_R2 3 SPLGGGGGSGASSQAACLK 19 0 J3QQY0;J3KSZ8;Q68DK7;Q68DK7-2 J3QQY0 MSL1 Male-specific lethal 1 homolog 1 S(1)PLGGGGGSGASSQAACLK;S(1)PLGGGGGSGASSQAACLK;S(1)PLGGGGGSGASSQAACLK 178.1 8.190699999999999e-09 25714900.0 18597.5 15831.8 23628.2 29847.9 27328.5 23877.6 21653.6 24616.4 20502.6 21689.300000000003 True False 24511.118147969315 20949.119742277067 23314.874629608377 22966.927800458056 23534.40949924743 22384.5298973579 23580.72845141849 20812.501008597723 21586.325579112534 20929.964208709123 1.1711017708176512 1.0009152205601943 1.1139471810423294 1.097322841617729 1.1244362037396403 1.069496807263699 1.126649248717127 0.9943877973731784 1.0313598897665717 1.0 14.353282224064142 -7.767291067811605 24.99997181408595 1.009655361249973 1.096835619947053 0.49244441612865186 0.04266696802605425 122.64342507128104 523953.96636012086 0.021230871547573138 0.010631468547990278 1.7088696324210163e-08 7.767291067811605 0.08718025869708002 S(ph)PLGGGGGSGASSQAACLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPLGGGGGSGASSQAACLK 19 0 J3QQY0;J3KSZ8;Q68DK7;Q68DK7-2 J3QQY0 MSL1 Male-specific lethal 1 homolog 1 S(1)PLGGGGGSGASSQAACLK;S(1)PLGGGGGSGASSQAACLK;S(1)PLGGGGGSGASSQAACLK 204.63 2.3339e-20 16711500.0 24659.1 21698.4 25961.600000000002 33313.4 31109.300000000003 29407.5 27209.4 27877.8 23830.300000000003 20082.7 True False 28833.39859057453 23852.47375227015 26580.623003916287 31446.958201500034 25013.655984978624 27865.318931054964 24631.928653003222 27146.037288970678 24178.77305500167 23723.53453543427 1.2153921898740676 1.0054350761537363 1.1204326642058573 1.325559568475338 1.0543815023691931 1.1745854686802417 1.0382908422103858 1.1442661399558502 1.0191893210047365 1.0 14.534031350515091 -8.163949105278043 0.7917551420292821 0.998234277395852 1.1453129992351654 0.24551339846686082 0.0879587578300425 0.9415315922514005 1.242697323893196 0.0831945082462406 0.03314177637769133 6.855685631330953e-09 8.163949105278043 0.14707872183931336 S(ph)PLGGGGGSGASSQAACLK ddPTM_PC-9_Lapatinib_30min_R1 4 SPLGGGGGSGASSQAACLK 19 0 J3QQY0;J3KSZ8;Q68DK7;Q68DK7-2 J3QQY0 MSL1 Male-specific lethal 1 homolog 1 S(1)PLGGGGGSGASSQAACLK;S(1)PLGGGGGSGASSQAACLK;S(1)PLGGGGGSGASSQAACLK;S(1)PLGGGGGSGASSQAACLK 247.28 1.2193999999999997e-136 30824000.0 47527.2 37395.5 42069.6 39705.8 41495.5 39563.0 36308.0 37307.8 43939.6 27935.0 True False 46849.45341257894 37308.91301732269 38610.79988135222 42625.896986665946 39054.8162732919 37870.982715857455 38187.85058359161 39041.25658681996 38990.65954349937 32763.52752895226 1.4299270239194886 1.1387330922884842 1.1784689498782719 1.301016715889294 1.192021104527899 1.1558884397411686 1.1655597996841462 1.1916072392485892 1.190062929244855 1.0 14.999803074579384 -14.52287874278744 0.06223031509494611 0.2836632913572579 1.50495597673035 0.5031259967841881 0.07404099922532975 348.5507038544256 1.573693195662953 37.95281753709212 5.8985567712538955 3.0000000172203206e-15 14.52287874278744 1.221292685373092 S(ph)PLGSVR ddPTM_PC-9_AZD4547_30min_R2 4 SPLGSVR 7 0 Q92620;J3KSA8;H3BMS7;Q92620-2 Q92620 DHX38 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 1 S(1)PLGSVR;S(1)PLGSVR;S(1)PLGSVR;S(0.999)PLGS(0.001)VR 95.815 0.013005000000000001 34408400.0 34344.2 29665.3 48276.0 59259.0 59837.0 50443.1 34734.3 57753.0 35098.9 50855.0 True False 45264.9411962623 39254.02808844046 47635.828697021956 45597.7530924234 51529.665411803355 47288.88498280458 37825.58541074488 48828.60088191388 36954.156198175486 49074.58192905727 0.9223703884364776 0.7998851247512713 0.9706823130125655 0.9291521455718154 1.0500275985294216 0.9636125897346591 0.7707775374515864 0.9949876078924323 0.7530202957530397 1.0 15.582688356839572 -10.38062793948194 16.694639726105525 0.9999999998162904 0.9100785797765915 0.07967622526753915 0.09490181535973535 0.0 0.0 0.09032583697037483 0.021907233326539776 4.162670742006203e-11 10.38062793948194 -0.08992142003969894 S(ph)PLGSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPLGSVR 7 0 Q92620;J3KSA8;H3BMS7;Q92620-2 Q92620 DHX38 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 1 S(0.999)PLGS(0.001)VR;S(1)PLGSVR 112.41 0.009174 16733800.0 17878.6 23518.4 24728.0 26308.0 33750.0 35963.0 26491.0 26900.0 23313.0 24996.0 True False 20905.09386155399 25853.15132430916 25317.609301462224 24834.048051686794 27136.929776402194 34077.03697075675 23981.580701768813 26193.90350290595 23653.908521137113 29527.576931772863 0.7079854168141805 0.8755595280996501 0.8574225159064595 0.8410459181621625 0.9190367986884073 1.1540749533731123 0.8121757080569543 0.8870996615614691 0.801078550258032 1.0 14.8497753516006 -3.869150906773754 0.871438585701807 0.9169275364468898 2.847726423030183e-19 0.27895889970331345 0.09801909151962417 13.78407223034082 2.511082982129354 0.03490565549508045 17.607155868181554 0.00013516028324653208 3.869150906773754 -0.9169275364468898 S(ph)PLGSVR ddPTM_PC-9_Lapatinib_30min_R1 4 SPLGSVR 7 0 Q92620;J3KSA8;H3BMS7;Q92620-2 Q92620 DHX38 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 1 S(1)PLGSVR;S(1)PLGSVR;S(1)PLGSVR;S(0.999)PLGS(0.001)VR 98.58200000000001 0.012116 30472000.0 39607.7 41328.9 58298.0 45664.7 49169.4 39709.1 42316.5 40882.0 48087.4 32632.2 True False 39042.886934837385 41233.20547129004 53504.963476787794 49023.03437097357 46277.352562759756 38010.83435943322 44507.44131377528 42781.52696707854 42671.29062922906 38272.632290326685 1.0201254682110115 1.077354835656591 1.3979953892617687 1.2808900626196025 1.2091499798527379 0.9931596570388069 1.1629051531170598 1.117809892001901 1.1149296004919453 1.0 15.22402550871377 -6.721571823300339 24.87901329868871 1.0904454711855645 1.206266110535377 0.2258574943410544 0.10855746660437969 255.46250178434684 159418.329149944 0.038522511175352804 0.03852195187897173 1.8985768309039506e-07 6.721571823300339 0.11582063934981246 S(ph)PLHIKDDVLPK ddPTM_PC-9_AZD4547_30min_R2 1 SPLHIKDDVLPK 12 1 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 S(1)PLHIKDDVLPK 59.248000000000005 0.030625 4869500.0 31872.0 22853.0 34865.0 26118.0 30333.0 32475.0 31920.0 34175.0 33508.0 31023.0 True False 42006.63302121674 30239.785335227665 34402.667319613676 20096.898619077503 26121.78653569248 30444.333116255308 34760.81816276639 28894.039013374302 35279.16447206222 29936.894212666284 1.4031727113310155 1.0101176535017191 1.149172892659584 0.671308736180606 0.8725616742380834 1.0169502854900134 1.161136419691095 0.9651648834416915 1.1784510517839766 1.0 14.869636937071347 -4.425583792739542 1.8755887796642314 0.9905322047296284 2.036417275535614 0.4044013924631594 0.14441646236435007 3.070396551233126 4.695174170653775 0.0407052241893855 7.830540674262083 3.7533253085976683e-05 4.425583792739542 1.0458850708059857 S(ph)PLHIKDDVLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPLHIKDDVLPK 12 1 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 S(1)PLHIKDDVLPK;S(1)PLHIKDDVLPK 68.44 0.014542 3988500.0 57521.0 77828.0 61375.0 59930.0 60993.0 54375.0 69046.0 52504.0 55093.0 46751.0 True False 67258.1692084642 85554.24949266667 62838.412765983645 56572.316395681526 49041.859491913994 51523.479278283194 62505.4630302491 51125.82563258637 55898.630899283955 55226.58621928764 1.2178585317840012 1.5491497003446364 1.1378290252537393 1.024367433667734 0.888011786518616 0.9329470243498204 1.1318002308174417 0.9257466219183199 1.012168861521294 1.0 15.753075330845446 -5.506526299001974 3.6310895486865684 0.9863715386447824 1.3833113137427573 0.7156455323563606 0.09853837351171474 0.10816792905132049 3.041884686060174 0.026024522078618675 0.054175447061123365 3.115112252490511e-06 5.506526299001974 0.39693977509797485 S(ph)PLHIKDDVLPK ddPTM_PC-9_Lapatinib_30min_R1 2 SPLHIKDDVLPK 12 1 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 S(1)PLHIKDDVLPK;S(1)PLHIKDDVLPK 75.589 0.0092387 14671200.0 73611.0 92886.0 80981.0 67875.0 71111.0 82913.0 76162.0 76273.0 76128.0 62970.0 True False 72561.293641396 92670.92817389898 74323.05477569989 72866.75392436225 66928.39078960515 79367.0042696431 80105.29569647185 79816.92202827605 67553.66297662063 73854.28059774915 0.9824927283037869 1.2547807307017937 1.0063472851425355 0.9866287144713315 0.9062222290693456 1.0746432519181828 1.0846398482001218 1.080735217813612 0.9146885248880138 1.0 16.172393921638665 S(ph)PLHVGETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPLHVGETR 9 0 O15164-2;O15164 O15164-2 TRIM24 Transcription intermediary factor 1-alpha 1 S(1)PLHVGETR 77.124 0.013327 3614800.0 16830.0 36016.0 23959.0 21780.0 25735.0 22300.0 20469.0 11760.0 15076.0 18866.0 True False 19678.98659234804 39591.430458548166 24530.273425013478 20559.73721171271 20692.411490243267 21130.548743093623 18530.02813727325 11451.312460749965 15296.457979010125 22286.256456826184 0.8830099676215676 1.7764953272994164 1.1006906194647132 0.9225298672992408 0.9284830554799287 0.9481425821348038 0.8314553937387534 0.5138284432351345 0.6863628267332842 1.0 14.443866679200193 -5.683743234645011 2.7253446655880555 0.8124756333324418 1.3473893108882342 0.4018615113073397 0.2429720592300232 0.23862884816300353 3.576857265552708 0.06939807023983441 0.13231073449579792 2.071365628078993e-06 5.683743234645011 0.5349136775557924 S(ph)PLIESTANMDNNQSQK ddPTM_PC-9_AZD4547_30min_R2 1 SPLIESTANMDNNQSQK 17 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 S(0.999)PLIES(0.001)TANMDNNQSQK 147.49 1.207e-11 0.0 10529.0 11587.0 11295.0 10960.0 14345.0 15584.0 15408.0 15140.0 17660.0 13484.0 True False 13877.002983194987 15332.27115386528 11145.220919978097 8433.341330312025 12353.444362724058 14609.530016434874 16779.282150748873 12800.460882589234 18593.471546395453 13011.929264210174 1.066483124940145 1.1783242010112442 0.8565386956593338 0.6481238223072934 0.949393753369279 1.1227796985201084 1.2895306921857432 0.9837481147240331 1.4289557811797773 1.0 13.667547264245975 -6.809452506562949 4.260322987849588 1.1770148425206586 0.9310184997794243 0.29259420131323266 0.17620529790057457 0.2856573715638762 10.876675140086075 0.06592892132054824 0.0595304296566015 1.550770366171391e-07 6.809452506562949 -0.24599634274123428 S(ph)PLIESTANMDNNQSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPLIESTANMDNNQSQK 17 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 S(0.898)PLIES(0.078)T(0.025)ANMDNNQSQK 90.37899999999999 0.0021098000000000002 3880700.0 19989.0 37855.0 31875.0 29563.0 29968.0 23497.0 27236.0 18800.0 22156.0 22163.0 True False 23372.742899254015 41612.99422502054 32635.02088661068 27906.68095453916 24095.985527088 22264.775955895544 24656.00890843589 18306.51992024655 22479.98958496606 26180.97645778852 0.8927376309641388 1.5894362951707701 1.2465165666845157 1.0659144436240942 0.9203623694455345 0.850418088561095 0.9417528390581105 0.6992298377320675 0.8586383178339606 1.0 14.676231285256533 -6.042212150574323 2.0910449460772704 0.8597795318778804 1.2788627575754317 0.46929369215758465 0.1733435124514846 0.24902082981802512 2.170074610776192 0.0539021847552312 0.08206318308460442 9.073771729130013e-07 6.042212150574323 0.4190832256975513 S(ph)PLIESTANMDNNQSQK ddPTM_PC-9_Lapatinib_30min_R1 1 SPLIESTANMDNNQSQK 17 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 S(0.997)PLIES(0.003)TANMDNNQSQK 228.32 3.5419e-29 4588800.0 4798.1 10223.0 5974.1 5649.1 11377.0 9550.8 6227.3 8667.9 9565.3 9809.7 True False 4729.678214136225 10199.329271599245 5482.932558692888 6064.5536588451705 10707.827228042603 9142.334548002218 6549.719123587084 9070.642277724677 8487.95518692557 11505.293574396377 0.4110871385899743 0.8864901365312924 0.47655737971732276 0.5271098577042043 0.9306870058380398 0.7946198407615921 0.5692787481896753 0.7883885986108413 0.7377434684339108 1.0 13.490010176055575 -14.522878613423046 0.0742424317602642 2.043078599499642 0.33873446319901285 0.3301261866444073 0.15850936566938645 368.7233639603003 1.9501845913283997 64.652573458221 7.084856235119302 3.0000009108380394e-15 14.522878613423046 -1.704344136300629 S(ph)PLLAGGS(ph)PPQPVVPAHK ddPTM_PC-9_Lapatinib_30min_R1 1 SPLLAGGSPPQPVVPAHK 18 0 Q8NFH5-2;Q8NFH5;C9IYQ7;F8WCF5;F8WEL4;C9JIY9 Q8NFH5-2 NUP35 Nucleoporin NUP53 2 S(1)PLLAGGS(1)PPQPVVPAHK 70.17399999999999 0.022959999999999998 0.0 8263.5 12576.0 14163.0 13021.0 13714.0 14070.0 11762.0 10375.0 13007.0 9321.7 True False 8145.660974659695 12546.881044667134 12998.572810761012 13978.60777678266 12907.369482761384 13468.258898771954 12370.978808091999 10857.060375799625 11542.014690217866 10932.943424615503 0.7450565376858855 1.147621510271228 1.1889362549425389 1.2785767961910284 1.1805941896397691 1.2318968804364423 1.1315323172933247 0.993059229718044 1.055709724449048 1.0 13.416394242811508 -10.292235142441655 8.250952706511416 0.9999999999382583 1.1179755147168913 0.04060646054640171 0.1439929569649015 0.0 0.0 0.14365261751830996 0.03484087737790859 5.102286692696256e-11 10.292235142441655 0.117975514778633 S(ph)PLLEVK ddPTM_PC-9_Lapatinib_30min_R1 2 SPLLEVK 7 0 A0A140T9E6;A2AB20;Q9BW19 A0A140T9E6 KIFC1 Kinesin-like protein KIFC1 1 S(1)PLLEVK;S(1)PLLEVK 95.50200000000001 0.013106 3532200.0 26727.0 38262.0 30688.0 24161.0 32524.0 32122.0 31702.0 31788.0 33710.0 26437.0 True False 26345.86807886849 38173.406689810276 28164.951099105696 25937.88053873327 30611.00226464423 30748.21694003927 33343.37444092268 33264.986527799345 29913.224817962928 31006.600224911774 0.8496858052080573 1.2311380935966156 0.908353411686748 0.8365277183112091 0.9872414918953383 0.9916668295460233 1.0753637676836771 1.0728356635847198 0.9647373333736089 1.0 14.920287727249418 -7.002888321336721 3.8603795180875027 1.0346023482451727 0.9683450830778161 0.07433958061269319 0.1066696275098702 0.6680568932251516 22.307496300356178 0.04185030817209315 0.03427402258486895 9.933714606788118e-08 7.002888321336721 -0.06625726516735664 S(ph)PLLLGAQR ddPTM_PC-9_AZD4547_30min_R2 1 SPLLLGAQR 9 0 Q96DR7;Q96DR7-4;Q96DR7-3 Q96DR7 ARHGEF26 Rho guanine nucleotide exchange factor 26 1 S(1)PLLLGAQR 75.652 0.025660000000000002 3041500.0 6110.9 7364.4 8706.6 9220.3 8966.2 8002.3 8564.3 10967.0 8469.2 7468.9 True False 8054.039085383822 9744.79828130883 8591.144795208622 7094.702287214962 7721.3978978777595 7501.914915972589 9326.506108752512 9272.302146588916 8916.864621785518 7207.416084356228 1.1174655370411037 1.3520515767724326 1.191986794526237 0.9843614138795299 1.0713129098564373 1.0408605286790054 1.2940152198227866 1.2864946380318663 1.2371791107134313 1.0 12.815266419242082 -10.637927455706484 5.888403291220126 0.9999989236325614 1.1749490079275562 0.17451440042118327 0.11423463734244381 1.7774753712214348e-06 2.6723775315174225e-07 0.1218017353541948 0.029541078218821123 2.3018262809985428e-11 10.637927455706484 0.1749500842949948 S(ph)PLLLGAQR ddPTM_PC-9_Lapatinib_30min_R1 1 SPLLLGAQR 9 0 Q96DR7;Q96DR7-4;Q96DR7-3 Q96DR7 ARHGEF26 Rho guanine nucleotide exchange factor 26 1 S(1)PLLLGAQR 75.387 0.026045999999999996 2739700.0 8321.0 7439.5 7133.0 6759.9 4798.2 7018.0 4575.2 5645.9 5842.2 4550.7 True False 8202.341014115489 7422.274294831521 6546.552274176253 7257.045596365341 4515.979309624154 6717.856499757044 4812.08146937447 5908.229125371285 5184.1899149066485 5337.282431573405 1.5368010067433284 1.3906467176861521 1.2265703301457782 1.3596892593570318 0.8461196062830171 1.258666106934246 0.9015976821664825 1.106973296076739 0.9713163920722806 1.0 12.381889640723065 -5.076409717364656 0.5632508888874752 1.001173577848974 1.7735730639264027 0.649556199418325 0.12949754316454973 1.787714345699334 0.5452007502895251 0.07051089713753694 0.8651272499219914 8.386684057831654e-06 5.076409717364656 0.7723994860774286 S(ph)PLLNSPTVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPLLNSPTVAK 11 0 O43365 O43365 HOXA3 Homeobox protein Hox-A3 1 S(0.537)PLLNS(0.413)PT(0.05)VAK 122.33 0.0006803 10904000.0 28387.0 24564.0 28123.0 28025.0 40443.0 45946.0 43741.0 32792.0 37341.0 36896.0 True False 33192.358431193315 27002.551582179505 28793.55897707143 26454.85010827589 32518.4844725047 43536.510876689674 39597.53582258387 31931.24474599599 37887.04148276846 43584.95273142469 0.7615554532255274 0.6195383931829002 0.6606307262623532 0.6069720958812003 0.7460942925162087 0.9988885647064133 0.9085139099860513 0.7326208414807712 0.8692688441406053 1.0 15.411542524490569 -6.5544301202033175 6.576097430699767 0.8851709034491825 0.660809161468744 0.6638600267669961 0.08062507696720209 0.11786999572412753 15.940978087633221 0.027331316098644105 0.027649392273297626 2.789779507406847e-07 6.5544301202033175 -0.22436174198043846 S(ph)PLLNSPTVAK ddPTM_PC-9_Lapatinib_30min_R1 1 SPLLNSPTVAK 11 0 O43365 O43365 HOXA3 Homeobox protein Hox-A3 1 S(0.905)PLLNS(0.086)PT(0.009)VAK 92.781 0.007459899999999999 16891000.0 98449.0 87146.0 97496.0 90062.0 135490.0 117930.0 102530.0 105250.0 130410.0 108080.0 True False 97045.09920666466 86944.21879123434 89480.25522544328 96685.45991802472 127520.74458358911 112886.40880825692 107838.50171685709 110140.29923401523 115721.85252181983 126761.48399245265 0.7655724448006833 0.6858883002380358 0.7058946645873199 0.7627353110175118 1.0059896789405027 0.8905418684983063 0.8507197795450058 0.868878272524586 0.9129102064528519 1.0 16.951756928951042 -6.091870587906154 5.690470732430439 0.909351365137249 0.7184092581751506 0.7689061909669714 0.05154596937855913 0.1118305618932009 5.501917030982928 0.01550116707912812 0.020295804614066514 8.093370314071739e-07 6.091870587906154 -0.19094210696209846 S(ph)PLLSPDMK ddPTM_PC-9_AZD4547_30min_R2 1 SPLLSPDMK 9 0 A0A0C4DGS2;Q9Y215-7;Q9Y215-6;Q9Y215-8;Q9Y215-2;Q9Y215-5;Q9Y215 A0A0C4DGS2 COLQ Acetylcholinesterase collagenic tail peptide 1 S(1)PLLSPDMK 73.233 0.026545 11766000.0 24056.0 23786.0 28695.0 29161.0 38895.0 30257.0 26129.0 29474.0 32558.0 27688.0 True False 31705.307604116148 31474.359339418283 28314.485551020083 22438.381982958843 33495.10062657038 28365.025006883334 28454.43038141988 24919.470545141026 34278.949411525646 26718.651547571295 1.1866357681886135 1.17799205859546 1.0597273406783827 0.8398021862371446 1.253622420537726 1.0616188828384827 1.0649650612329036 0.9326619833629362 1.2829595591863459 1.0 14.705559578427213 -5.25757977499757 7.4066071471132275 1.0584373326650363 1.1828763711738528 0.12929040939159941 0.12474834658599858 0.24210886712701368 108.10841183167778 0.03128795950275534 0.0748546590195155 5.526118900500247e-06 5.25757977499757 0.12443903850881655 S(ph)PLPGPSEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPLPGPSEEK 10 0 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 S(1)PLPGPSEEK 80.737 0.017245 7200600.0 33095.0 50734.0 46732.0 31774.0 44027.0 35512.0 43581.0 29107.0 29233.0 33462.0 True False 38697.32984395477 55770.53623067476 47846.268112096914 29993.805792697876 35400.22540046395 33649.68820469689 39452.69218088354 28342.972091415733 29660.47732159746 39528.395714953745 0.978975471785095 1.4108980448598514 1.2104277759493407 0.7587913764319837 0.8955644356462437 0.851278874238933 0.9980848316077354 0.7170281408788234 0.7503587430029898 1.0 15.270601783200592 -5.7517253334620495 24.868664654870873 0.848969813819675 1.2211803624678812 0.5866116815676222 0.1331384054165079 120.12868491469085 307534.8846979022 0.035202967332488136 0.05999452900995933 1.7712288055540606e-06 5.7517253334620495 0.37221054864820624 S(ph)PLPTKR ddPTM_PC-9_Lapatinib_30min_R1 1 SPLPTKR 7 1 D6R9T3;E7EMP6;Q96FZ2 D6R9T3 HMCES Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein 1 S(1)PLPTKR 60.76 0.033807 64326000.0 20817.0 19033.0 18864.0 18877.0 20589.0 18151.0 14458.0 17688.0 22253.0 16420.0 True False 20520.145762629745 18988.93025788403 17313.074737145776 20265.277551825995 19377.995499531444 17374.724042047605 15206.564496462686 18509.849053218673 19746.632805521487 19258.17512172529 1.0655290874097836 0.9860191912193423 0.8989987175687674 1.0522948007137283 1.0062217929294341 0.9021999193707119 0.7896160669609888 0.9611424206199878 1.0253636536540351 1.0 14.23318338140316 -6.754904472805545 24.94795240014959 0.9241077898020644 0.9980279816067088 0.1601922529765174 0.07312411082417557 273.5427458221578 1044288.0047180009 0.02568986807001913 0.025113108973404418 1.758310328476389e-07 6.754904472805545 0.07392019180464438 S(ph)PLSALAR ddPTM_PC-9_AZD4547_30min_R2 2 SPLSALAR 8 0 Q9BQG0;Q9BQG0-2;I3L1L3;I3L2H8 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 S(1)PLSALAR;S(1)PLSALAR 122.96 0.0033058 34580000.0 12391.7 13091.7 16484.2 15160.5 14137.099999999999 13165.3 7757.0 18074.5 12291.9 12953.599999999999 True False 16332.002836628113 17323.336002853022 16265.608737415067 11665.480952390097 12174.407689108828 12342.071709790174 8447.357972699832 15281.50133569083 12941.624739588793 12500.098406768973 1.3065499410615928 1.38585597001958 1.3012384549394442 0.9332311292903966 0.9739449477066693 0.9873579637666512 0.675783317683761 1.222510482590736 1.035321828553024 1.0 13.609651832068712 -5.721930484358481 5.95007082285371 0.9724409389708943 1.3420185049988669 0.6226538250751804 0.1269713364933618 0.12097249092517147 10.85511332356059 0.035625219407622255 0.06106604621992609 1.8970095430330485e-06 5.721930484358481 0.36957756602797254 S(ph)PLSALAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SPLSALAR 8 0 Q9BQG0;Q9BQG0-2;I3L1L3;I3L2H8 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 S(1)PLSALAR;S(1)PLSALAR;S(1)PLSALAR;S(1)PLSALAR;S(0.999)PLS(0.001)ALAR 117.01 0.0035650999999999994 38944900.0 22107.0 29870.800000000003 30784.100000000002 28836.9 22436.9 34125.3 29853.999999999996 22326.5 21503.699999999997 18482.4 True False 25849.278466847176 32836.17561476011 31518.10969334938 27221.261983491215 18040.550509634304 32335.709193842697 27026.012995757264 21740.453031882138 21818.15093149643 21833.1128134021 1.1839483763845065 1.5039621649645791 1.4435921237031404 1.2467879507672237 0.8262931018503346 1.48103980729645 1.2378451587154142 0.9957559976760125 0.9993147160446822 1.0 14.414230213969166 -6.8652031493704495 0.38524820927474385 0.9676871801783756 1.4206277205762587 0.2895203164624972 0.1876423891285099 2.039625224600632 0.6459711066153772 0.21634814272250738 0.35120155604891423 1.3639449765599234e-07 6.8652031493704495 0.4529405403978831 S(ph)PLSALAR ddPTM_PC-9_Lapatinib_30min_R1 4 SPLSALAR 8 0 Q9BQG0;Q9BQG0-2;I3L1L3;I3L2H8 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 S(1)PLSALAR;S(1)PLSALAR;S(0.998)PLS(0.002)ALAR;S(0.998)PLS(0.002)ALAR 86.882 0.012143000000000001 45868000.0 21126.2 17811.6 24040.1 15781.899999999998 15586.2 20928.699999999997 16310.5 14059.3 15604.9 15337.9 True False 20824.9365139294 17770.35833454145 22063.6157754696 16942.553572875062 14669.45035964821 20033.62828818256 17154.977882110572 14712.546403998042 13847.311835118071 17989.035578532912 1.1576460796364587 0.9878438594978145 1.2265035376214977 0.941826675416293 0.8154661930378243 1.1136577167088129 0.9536352189209266 0.8178618770177516 0.7697639917752268 1.0 14.13483022298354 -6.002548186730609 0.6333945784701679 0.8793666162849271 1.1463250343309315 0.34014506382885534 0.11780933756629781 1.3165864122434174 1.0026688098204108 0.07726345038316416 0.2100777966072457 9.94149762893247e-07 6.002548186730609 0.2669584180460044 S(ph)PLSGIPVR ddPTM_PC-9_AZD4547_30min_R2 2 SPLSGIPVR 9 0 Q5M775;Q5M775-4;J3KSG2 Q5M775 SPECC1 Cytospin-B 1 S(0.994)PLS(0.006)GIPVR;S(0.999)PLS(0.001)GIPVR 101.38 0.0056019 0.0 14871.3 16446.9 35829.0 66153.0 63264.0 38345.0 43001.0 69501.0 44489.0 42389.0 True False 19600.064057744105 21763.03878834096 35353.884049747256 50902.44790366165 54480.88561612926 35947.281088308235 46828.00569602497 58761.21742409731 46840.5977139064 40904.97401220744 0.4791608974472096 0.532038934478876 0.8642930329009975 1.244407291115027 1.331889016721299 0.8787997537311804 1.1447997909019547 1.4365298803651838 1.1451076267626417 1.0 15.319988663949491 -5.458924620886639 2.5542954318501194 1.180338800868566 0.49259504597702547 0.7570495384579697 0.1499508890793613 0.13753254395694087 1.7433753479030845 0.04382498353768932 0.10785579544369163 3.47596487425681e-06 5.458924620886639 -0.6877437548915406 down S(ph)PLSGIPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPLSGIPVR 9 0 Q5M775;Q5M775-4;J3KSG2 Q5M775 SPECC1 Cytospin-B 1 S(0.992)PLS(0.008)GIPVR;S(0.994)PLS(0.006)GIPVR 93.556 0.012193 3411200.0 24933.6 9203.699999999999 26930.6 30142.7 31686.0 14092.3 24549.0 29340.0 19924.9 19337.4 True False 29154.366018952416 10117.382510865717 27572.727638869233 28453.90224295193 25477.355759854192 13353.274979923688 22223.541000631256 28569.856088299664 20216.26396829259 22843.117545225836 1.2762866522588823 0.4429072560185739 1.207047487466608 1.245622546336664 1.1153186822863812 0.5845644734562291 0.9728768832289238 1.2506986418003485 0.8850045939774865 1.0 14.479471937435429 S(ph)PLSGIPVR ddPTM_PC-9_Lapatinib_30min_R1 2 SPLSGIPVR 9 0 Q5M775;Q5M775-4;J3KSG2 Q5M775 SPECC1 Cytospin-B 1 S(0.998)PLS(0.002)GIPVR;S(0.998)PLS(0.002)GIPVR 90.149 0.017676 0.0 15615.4 16274.1 27614.0 25699.0 25338.0 21223.7 27069.0 21840.0 33459.0 21609.0 True False 15392.721532486354 16236.418321327723 25343.683513122527 27588.990189350858 23847.66865642467 20316.011825861136 28470.500370365786 22854.766130839867 29690.49508111011 25344.08685781741 0.6073496204002494 0.6406393101639637 0.9999840852543971 1.0885770059157214 0.9409559235735034 0.8016075678652689 1.1233586962547846 0.901779032681554 1.1714959488450478 1.0 14.629361564410722 -5.251469736066437 6.107162326677131 0.9983673375852283 0.6199557208867227 0.6860515953491371 0.10268032471922843 0.08216845180076983 13.92208304563329 0.026053090289450315 0.06444898726406922 5.604414705255267e-06 5.251469736066437 -0.37841161669850565 S(ph)PLSPTETFSWPDVR ddPTM_PC-9_AZD4547_30min_R2 6 SPLSPTETFSWPDVR 15 0 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 S(1)PLSPTETFSWPDVR;S(1)PLSPTETFSWPDVR;S(0.964)PLS(0.032)PT(0.003)ET(0.001)FSWPDVR;S(1)PLSPTETFSWPDVR;S(0.672)PLS(0.194)PT(0.055)ET(0.025)FS(0.054)WPDVR;S(0.824)PLS(0.168)PT(0.006)ET(0.002)FSWPDVR 181.75 1.1546e-05 14559500.0 8590.8 7793.04 19818.7 27568.5 21075.3 19891.420000000002 12170.720000000001 20578.7 12724.300000000001 17787.1 True False 11322.495700259436 10311.987778796776 19555.89108869146 21213.00825407911 18149.35838115848 18647.606362905095 13253.89050219123 17398.734766482106 13396.8805208267 17164.37904297188 0.6596507611439367 0.6007783767172817 1.139329948361797 1.2358739107876426 1.0573850842911738 1.0864131068312977 0.7721741910388633 1.0136536091939887 0.7805048168236638 1.0 14.067130045301973 -5.252639680741197 24.835966452298457 1.0150537114094638 0.6302145103955636 0.553024711631406 0.13676822777763264 453.4493522910568 1279792.1110047468 0.03758209712564644 0.09624963385207078 5.589337305953795e-06 5.252639680741197 -0.3848392010139001 S(ph)PLSPTETFSWPDVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SPLSPTETFSWPDVR 15 0 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 S(1)PLSPTETFSWPDVR;S(1)PLSPTETFSWPDVR;S(0.798)PLS(0.088)PT(0.088)ET(0.024)FS(0.003)WPDVR;S(1)PLSPTETFSWPDVR;S(0.961)PLS(0.037)PT(0.001)ET(0.001)FSWPDVR 166.79 2.6195e-05 15651900.0 7693.42 11440.61 15742.59 15308.800000000001 13552.499999999998 12769.0 13968.78 11327.400000000001 6813.57 4993.74 True False 8995.764054028656 12576.358152442544 16117.95304970504 14451.097567799254 10896.984912435268 12099.371161460198 12645.556033190664 11030.067752372377 6913.205571241973 5899.065531575909 1.5249472998523341 2.1319237911708413 2.732289201303245 2.4497265694789983 1.847239169340807 2.05106573180039 2.1436541034343217 1.8697991560412017 1.1719153710426984 1.0 12.526270720537273 -8.216976219077175 2.1454208188008357 0.9878280060246134 2.1508954235353444 0.6470462064695071 0.3037903363301034 0.20656838143548334 1.7103955189704594 0.29998386765430574 0.08870844400045527 6.067695539224066e-09 8.216976219077175 1.163067417510731 S(ph)PLSPTETFSWPDVR ddPTM_PC-9_Lapatinib_30min_R1 6 SPLSPTETFSWPDVR 15 0 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 S(0.994)PLS(0.005)PTETFSWPDVR;S(1)PLSPTETFSWPDVR;S(0.997)PLS(0.001)PT(0.001)ETFSWPDVR;S(1)PLSPTETFSWPDVR;S(0.955)PLS(0.035)PT(0.011)ETFSWPDVR;S(1)PLSPTETFSWPDVR 177.63 4.3965e-05 19380400.0 23762.719999999998 16695.74 23645.899999999998 17146.87 15356.970000000001 12845.810000000001 11602.400000000001 10601.15 13194.7 8331.75 True False 23423.85925525085 16657.082039813216 21701.825377813577 18407.908020081493 14453.703217564676 12296.424651345675 12203.115501020799 11093.718130400783 11708.57393964923 9771.881886140967 2.397067374348014 1.704593059340722 2.220844012512301 1.8837628447176202 1.4791115351142068 1.2583476544866097 1.2487989154195511 1.1352693636355264 1.1981902847449464 1.0 13.254420710351935 -6.378030727659553 1.4873363152107475 1.1578805293696837 2.0883983475971646 0.8544128633264031 0.17409554918453227 0.14066777079776502 0.6265351635053492 0.06406444351054015 0.07986407619894487 4.18763935243733e-07 6.378030727659553 0.9305178182274809 S(ph)PLSQGDSSAPSLPK ddPTM_PC-9_AZD4547_30min_R2 2 SPLSQGDSSAPSLPK 15 0 Q92793;Q92793-2 Q92793 CREBBP CREB-binding protein 1 S(0.999)PLS(0.001)QGDSSAPSLPK;S(0.933)PLS(0.022)QGDS(0.022)S(0.022)APSLPK 90.259 0.0042761000000000006 15414900.0 34078.5 39079.0 45157.0 36374.0 35441.7 41942.0 42858.0 61803.0 48599.0 39070.6 True False 44914.754123165585 51710.522518503596 44558.18867494035 27988.536272697947 30521.231723273417 39319.360109683745 46672.278973052664 52252.76644165536 51167.843923175074 37702.750186165096 1.191285885018725 1.3715318448434726 1.1818286054710894 0.7423473389739152 0.8095226892618853 1.0428777719274138 1.237901180752032 1.3859139236168863 1.3571382371451235 1.0 15.202382142704645 -9.774090485214762 11.910488272809548 0.999998968523188 1.1392048760566373 0.04005622034705947 0.21261972129448403 0.0 0.0 0.23659791595794896 0.057383423429154944 1.682323512606564e-10 9.774090485214762 0.1392059075334493 S(ph)PLSQGDSSAPSLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPLSQGDSSAPSLPK 15 0 Q92793;Q92793-2 Q92793 CREBBP CREB-binding protein 1 S(0.798)PLS(0.201)QGDSSAPSLPK 81.992 0.0082535 4832200.0 26068.0 29848.0 30341.0 27667.0 29684.0 20285.0 25883.0 21978.0 22322.0 21747.0 True False 30480.797533531128 32811.112181440076 31064.444508883258 26116.90768762422 23867.63328837696 19221.218890298387 23431.17486330761 21401.100787615876 22648.41702092492 25689.55895084273 1.1865052876873632 1.277215862063826 1.2092245167900872 1.0166351138063223 0.9290791381061837 0.7482113230156427 0.9120894176557658 0.8330661039594776 0.8816195351684679 1.0 14.648894501205303 -5.954524588712378 1.9913319472977373 0.8677027105086648 1.239573278267476 0.8457466452626956 0.06497826346350682 0.10923506361529094 0.8757073591971972 0.019961783743482633 0.03303271746011223 1.1103896659530877e-06 5.954524588712378 0.3718705677588112 S(ph)PLSQGDSSAPSLPK ddPTM_PC-9_Lapatinib_30min_R1 2 SPLSQGDSSAPSLPK 15 0 Q92793;Q92793-2 Q92793 CREBBP CREB-binding protein 1 S(0.982)PLS(0.01)QGDS(0.004)S(0.004)APSLPK;S(0.999)PLS(0.001)QGDSSAPSLPK 73.833 0.016796000000000002 19093200.0 74242.0 82363.0 90907.0 69011.0 89733.0 86199.0 91136.0 75275.0 88362.0 71398.0 True False 73183.2954656846 82172.29353386762 83432.97737116792 74086.2991539472 84455.08136186567 82512.46970968318 95854.57614812716 78772.55130489786 78409.74106688949 83739.04916814514 0.8739446673049159 0.9812900235930369 0.9963449334567599 0.8847282109113092 1.0085507561983749 0.9853523598530594 1.1446819267753383 0.9406907779275745 0.9363581488660734 1.0 16.353612916350023 -6.3065708320700615 24.295645677254704 1.0058813802506408 0.9418970070810773 0.2100933150379075 0.06419830469745032 562.9564550775866 303055.10698400415 0.020526728351665125 0.023275233559252057 4.936613970554597e-07 6.3065708320700615 -0.06398437316956351 S(ph)PLTGYVR ddPTM_PC-9_AZD4547_30min_R2 3 SPLTGYVR 8 0 H0YNS8;H0YKM5;Q9NP66 H0YNS8 HMG20A High mobility group protein 20A 1 S(0.999)PLT(0.001)GYVR;S(1)PLTGYVR;S(1)PLTGYVR 97.565 0.0057740000000000005 112642300.0 39584.2 40575.6 39665.5 55642.0 61420.0 63620.0 62232.0 60669.0 45022.0 56164.0 True False 52171.15219749144 53690.86920089548 39139.50955302271 42814.59656033046 52892.893186372334 59641.83134276096 67770.52744064163 51294.00008492777 47401.771005765324 54197.715454991114 0.9626079579095425 0.9906481989168613 0.722161611876914 0.7899705033856298 0.975924773624409 1.1004491765393867 1.2504314410986963 0.9464236574238124 0.874608285752016 1.0 15.725944419851501 -6.484583416398676 5.707264278319395 1.0443076582439184 0.8659270829576768 0.31238936235218895 0.11721464154055847 0.2545910492353384 22.477184096096256 0.040904186207310636 0.04518189483606781 3.2765483699664995e-07 6.484583416398676 -0.17838057528624152 S(ph)PLTGYVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPLTGYVR 8 0 H0YNS8;H0YKM5;Q9NP66 H0YNS8 HMG20A High mobility group protein 20A 1 S(0.996)PLT(0.004)GYVR;S(0.997)PLT(0.003)GYVR;S(0.998)PLT(0.002)GYVR 96.665 0.0060501999999999995 88599000.0 31630.1 46605.0 44105.1 44537.0 32154.5 38939.7 53961.0 29117.1 31137.6 33077.6 True False 36984.45120704859 51231.636398285154 45156.73285352322 42041.73628090219 25854.0565480096 36897.63358257591 48849.42343619139 28352.806977117594 31592.928493448257 39074.30703786249 0.9465158568573242 1.3111335883357411 1.1556630501410285 1.0759432340070496 0.6616638530008314 0.9442939972504845 1.2501673641673783 0.7256125348465962 0.8085345816327625 1.0 15.25393266756891 -6.016389205096809 23.2522612485234 0.9012953368254725 1.1485565584875614 0.2922070505624569 0.1724812098382382 363.39446935135254 515570.00508517964 0.0516513569101698 0.06873082515008211 9.629656483246229e-07 6.016389205096809 0.24726122166208897 S(ph)PLTGYVR ddPTM_PC-9_Lapatinib_30min_R1 1 SPLTGYVR 8 0 H0YNS8;H0YKM5;Q9NP66 H0YNS8 HMG20A High mobility group protein 20A 1 S(0.998)PLT(0.002)GYVR 95.523 0.0064005 47255000.0 9862.0 7507.7 8606.8 5937.0 8963.8 5918.4 5109.3 8066.2 12780.0 2878.6 True False 9721.366071530698 7490.316381921717 7899.182127208777 6373.62678525141 8436.56690750886 5665.28382846424 5373.8345540031 8440.985099110829 11340.581820633832 3376.1621745066054 2.87941324173842 2.2185890353493924 2.339692739541805 1.8878319392885374 2.4988630496524613 1.678024791357118 1.5916991768289197 2.5001716928317874 3.3590157209468625 1.0 11.721168490465773 -2.5505756810957076 1.199023412524531 2.1243784020009793 178.05658907180862 0.1267360281305524 0.6044557017084414 806.5767476548095 6.659863988665142 0.17824589037251254 385053.3467658525 0.0028146494854873042 2.5505756810957076 175.93221066980763 S(ph)PLTQEQLIPNLAMK ddPTM_PC-9_AZD4547_30min_R2 3 SPLTQEQLIPNLAMK 15 0 Q9UNE7;Q9UNE7-2;H3BTA3 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 S(0.996)PLT(0.004)QEQLIPNLAMK;S(0.994)PLT(0.006)QEQLIPNLAMK;S(0.685)PLT(0.315)QEQLIPNLAMK 137.17 3.4339e-05 24572000.0 106580.0 116712.0 160732.0 145393.0 128168.0 160394.0 127585.0 180320.0 126815.0 134044.0 True False 140470.22299828325 154436.8715724452 158600.58865957687 111874.89014945769 110374.0855407191 150364.5378244392 138939.8178351047 152455.6873413798 133518.18200204617 129351.16035981831 1.0859602852230692 1.1939349530599148 1.2261242049811918 0.8648928222851144 0.853290262210943 1.1624521759694124 1.0741288864252432 1.1786186294525014 1.0322147990836448 1.0 16.98093347038329 -5.722845464067572 24.99993334726109 1.0318863713227984 1.1711993751973988 0.2805935638251704 0.10581208997741866 245.4625587632515 159001.20811661895 0.03149868500850679 0.05455598313429364 1.8930170951288837e-06 5.722845464067572 0.13931300387460044 S(ph)PLTQEQLIPNLAMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPLTQEQLIPNLAMK 15 0 Q9UNE7;Q9UNE7-2;H3BTA3 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 S(0.998)PLT(0.002)QEQLIPNLAMK;S(0.966)PLT(0.034)QEQLIPNLAMK 128.74 1.5073e-05 25568000.0 51035.0 72148.0 68222.0 55209.0 67086.0 47933.0 57101.0 47495.0 48406.0 44195.0 True False 59674.21751280345 79310.37663047896 69848.67121337587 52115.81871999299 53940.97988088054 45419.30909877608 51691.97990456005 46248.30657511218 49113.84617484506 52207.20365257249 1.14302650473146 1.5191462304373196 1.3379125164068062 0.9982495723542741 1.0332095210432253 0.8699816485294183 0.9901311751642333 0.8858606349208921 0.9407484549773428 1.0 15.671961265976963 -5.783533619453544 4.305437152587687 0.9514108027492805 1.3571851407098336 0.7577459142821728 0.09685208675143799 0.08655225119007232 3.6673040955408145 0.026434281887409847 0.04294662297939394 1.6461385310918327e-06 5.783533619453544 0.4057743379605532 S(ph)PLTQEQLIPNLAMK ddPTM_PC-9_Lapatinib_30min_R1 4 SPLTQEQLIPNLAMK 15 0 Q9UNE7;Q9UNE7-2;H3BTA3 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 S(0.992)PLT(0.008)QEQLIPNLAMK;S(0.993)PLT(0.007)QEQLIPNLAMK;S(0.957)PLT(0.043)QEQLIPNLAMK;S(1)PLTQEQLIPNLAMK 268.18 8.977399999999998e-62 26331500.0 147336.0 159155.0 150237.0 133169.0 157619.0 151663.0 146580.0 134820.0 148761.0 121040.0 True False 145234.96162188676 158786.48637595406 137885.09379159065 142962.69249876114 148348.16031087682 145176.72703372088 154169.19517855166 141084.2293846079 132005.96965722303 141961.6027243383 1.0230580581983473 1.1185171435707613 0.9712844258270074 1.0070518348286526 1.044987922536631 1.0226478445416378 1.085992213527753 0.993819643319792 0.9298709448466346 1.0 17.115141241842096 -7.9929747891059 24.14971477661011 0.9639054031660775 1.0380328466145194 0.3510999864012171 0.041428827683590755 111.6243866946884 383717.6936388426 0.02249622031075055 0.010763467225073136 1.0163076880522978e-08 7.9929747891059 0.07412744344844191 S(ph)PLYLVSR ddPTM_PC-9_AZD4547_30min_R2 2 SPLYLVSR 8 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 S(1)PLYLVSR;S(0.999)PLY(0.001)LVSR 92.23899999999999 0.0081241 5935800.0 4635.6 9895.3 9717.6 11846.7 9394.0 9241.5 7519.1 13445.900000000001 8604.4 9410.900000000001 True False 6109.624373530129 13093.762211861836 9588.738274632955 9115.62634469046 8089.805252243269 8663.62754407616 8188.285333573199 11368.145111044032 9059.211017769248 9081.427255455026 0.6727603714339289 1.441817661865505 1.0558624767789884 1.0037658275812198 0.890807691861859 0.9539940474524087 0.9016518112452715 1.251801593655383 0.997553662319716 1.0 13.148703336864715 -5.5243978961413225 24.238617231432297 1.0021771668844988 1.1051766719820861 0.005575900930153033 0.19684565737848614 111.82420434379283 1784178.4814573957 0.0514591856438761 0.09007386530352789 2.989524409973351e-06 5.5243978961413225 0.10299950509758737 S(ph)PLYLVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPLYLVSR 8 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 S(0.999)PLYLVS(0.001)R 72.096 0.033615 2555000.0 2204.5 6420.7 5657.1 3917.9 6243.7 4559.4 6610.3 1512.8 2061.0 3928.4 True False 2577.6783091403013 7058.104663071971 5791.986718671223 3698.3927650031806 5020.291805775472 4320.297037635025 5984.124529572392 1473.0906029440946 2091.138225971071 4640.58782280271 0.5554637488971165 1.5209505632864389 1.2481148810956277 0.7969664418007963 1.081822389204012 0.9309805573350309 1.2895186467903639 0.31743620834104 0.45061925467625685 1.0 12.180091847628939 -7.761293997858315 24.999999999120227 0.5380207740195443 1.071164874243519 0.33411037266924437 0.3019795336190074 3.883148361847876 668166.6456105986 0.1473468059946193 0.07809075536158612 1.7326306875038325e-08 7.761293997858315 0.5331441002239746 S(ph)PLYLVSR ddPTM_PC-9_Lapatinib_30min_R1 2 SPLYLVSR 8 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 S(0.999)PLY(0.001)LVSR;S(1)PLYLVSR 96.665 0.0060501999999999995 6367700.0 6137.2 8727.1 8920.7 5576.6 9999.400000000001 9182.900000000001 7534.599999999999 10130.3 8825.7 3258.8999999999996 True False 6049.6824025753585 8706.892936141423 8187.274480897819 5986.721766992256 9411.2549515768 8790.168773385425 7924.704720919063 10600.990720478356 7831.656727258838 3822.1965227887044 1.5827763869560174 2.2779814915923806 2.1420338886511043 1.5663040168913913 2.4622634904995087 2.2997689210841648 2.0733378500216775 2.7735336624564217 2.0489937345097053 1.0 11.90018624276912 -6.277510990894844 24.785935597877856 2.206016641510029 1.9376644298991146 0.020914235647826573 0.4811133233540802 2147.6551687803953 3312147.1990174423 0.14114593604030412 0.1605624275351355 5.278238487260008e-07 6.277510990894844 -0.2683522116109145 S(ph)PNELVDDLFK ddPTM_PC-9_AZD4547_30min_R2 4 SPNELVDDLFK 11 0 Q9UNZ2-4;Q9UNZ2;Q9UNZ2-5;F2Z2K0 Q9UNZ2-4 NSFL1C NSFL1 cofactor p47 1 S(1)PNELVDDLFK;S(1)PNELVDDLFK;S(1)PNELVDDLFK;S(1)PNELVDDLFK 155.06 0.00016469 33022100.0 90831.6 80103.9 102261.3 129828.0 126947.0 106197.8 98711.9 120210.0 103679.3 112441.4 True False 119714.15938535231 105995.91915785857 100905.24834565354 99898.16042260492 109322.60031472488 99557.23477793552 107497.06786971098 101634.3066509944 109159.57613251389 108504.86081049828 1.1033068794441463 0.9768771497064861 0.9299606265739806 0.9206791260446405 1.0075364319913258 0.9175370949676658 0.9907120019024088 0.9366797569419201 1.0060339722766802 1.0 16.727400148536255 -4.768225770978307 4.30650676406506 0.9602973051648133 1.1157059794492492 0.5955082535446248 0.03422280900142715 0.1339699354647946 5.152871559707788 0.008030036979112464 0.06493844305182535 1.7051957008153117e-05 4.768225770978307 0.15540867428443594 S(ph)PNELVDDLFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SPNELVDDLFK 11 0 Q9UNZ2-4;Q9UNZ2;Q9UNZ2-5;F2Z2K0 Q9UNZ2-4 NSFL1C NSFL1 cofactor p47 1 S(1)PNELVDDLFK;S(1)PNELVDDLFK;S(1)PNELVDDLFK;S(1)PNELVDDLFK;S(1)PNELVDDLFK;S(1)PNELVDDLFK 164.7 0.00010242 29705800.0 73268.7 91828.6 81685.8 92360.0 102183.9 81785.8 88614.5 91706.1 73274.0 68142.5 True False 85671.64378721143 100944.73653392465 83633.49926712146 87185.3686351602 82161.69832826385 77496.8086723277 80220.2930465776 89298.91204564457 74345.49362921117 80496.19583426675 1.0642943172569346 1.2540311438041036 1.0389745552611467 1.083099241294157 1.020690449737851 0.9627387713064791 0.9965724742041574 1.109355679733011 0.9235901505492354 1.0 16.296632984134213 -5.719035146699418 1.5128614770475854 1.0068009469910946 1.1547908900661454 0.4045223003540951 0.06734496322765282 0.390312596145493 1.790704078123708 0.020892550883203773 0.050222593825240386 1.909698703707439e-06 5.719035146699418 0.14798994307505087 S(ph)PNELVDDLFK ddPTM_PC-9_Lapatinib_30min_R1 5 SPNELVDDLFK 11 0 Q9UNZ2-4;Q9UNZ2;Q9UNZ2-5;F2Z2K0 Q9UNZ2-4 NSFL1C NSFL1 cofactor p47 1 S(1)PNELVDDLFK;S(1)PNELVDDLFK;S(1)PNELVDDLFK;S(1)PNELVDDLFK;S(1)PNELVDDLFK 161.49 0.00019503 43646000.0 31174.1 52819.2 54877.3 49508.399999999994 59799.4 54066.7 44125.1 47473.1 55264.8 61301.3 True False 30729.55161737023 52696.90038760197 50365.500226503915 53149.41289118093 56282.11686214387 51754.39327663353 46409.68177222753 49678.873535072074 49040.29625985639 71897.14802615228 0.42740988288148074 0.7329484108108669 0.7005215312321385 0.7392422975087699 0.7828143174979832 0.7198393079209218 0.645501011463573 0.690971407057782 0.6820895905637062 1.0 16.133646923369348 -14.522878745280336 0.33787661580135364 4.307608482920988 0.6768743563819134 0.5255783024214857 0.09139894556373358 322.02549905491196 2.7298057910643236 767.9186314306 0.07461540609109749 3.0000000000000132e-15 14.522878745280336 -3.6307341265390742 S(ph)PNLAGK ddPTM_PC-9_AZD4547_30min_R2 1 SPNLAGK 7 0 Q9Y4B5 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 S(1)PNLAGK 91.087 0.015491999999999999 8739800.0 37543.0 45577.0 57441.0 54206.0 65771.0 87481.0 80303.0 97597.0 80623.0 83823.0 True False 49480.89305708896 60308.87394318783 56679.29480871731 41709.64417435162 56639.83194009928 82010.79924074291 87449.8114324758 82515.62620594876 84884.56718488333 80888.38228373555 0.6117181684203148 0.7455814078669527 0.7007099562196829 0.5156444349207647 0.7002220880301621 1.0138761207149651 1.0811170771808052 1.0201171525041168 1.0494036941810776 1.0 16.303644887826053 -6.7460738614201885 4.391281399996653 1.0407980878233511 0.6499229079035632 0.9108087333219598 0.05937701141087424 0.057052425969449316 2.590049084991962 0.0214119395008977 0.02029297263574017 1.794428418481556e-07 6.7460738614201885 -0.39087517991978793 S(ph)PNQSLR ddPTM_PC-9_AZD4547_30min_R2 1 SPNQSLR 7 0 Q96B01-3;Q96B01-2;Q96B01 Q96B01-3 RAD51AP1 RAD51-associated protein 1 1 S(1)PNQSLR 91.265 0.015373 16494000.0 9053.1 8897.6 17520.0 14547.0 14184.0 14382.0 13625.0 21127.0 10986.0 11655.0 True False 11931.797483822069 11773.575197948716 17287.673352635356 11193.41389890958 12214.79643366177 13482.691266450614 14837.598604877569 17862.307600162665 11566.697531636482 11246.961997505905 1.0608907086614172 1.0468227064837234 1.5370971606793926 0.9952388832994903 1.0860529658027198 1.1987851714481208 1.3192539112489143 1.5881895576888907 1.0284286133625669 1.0 13.457247736277994 -7.061789478042074 5.269057255797642 1.2814272563468474 1.1520836436527937 0.018810848944614822 0.20866828702454882 0.6236446069898832 35.09308150806199 0.07965588768911075 0.062316130632251526 8.673822328264296e-08 7.061789478042074 -0.1293436126940537 S(ph)PNQSLR ddPTM_PC-9_Lapatinib_30min_R1 1 SPNQSLR 7 0 Q96B01-3;Q96B01-2;Q96B01 Q96B01-3 RAD51AP1 RAD51-associated protein 1 1 S(1)PNQSLR 86.882 0.018315 17783000.0 11462.0 14115.0 12260.0 3613.9 8079.3 10248.0 10455.0 3491.6 12690.0 10063.0 True False 11298.549778126635 14082.317584723021 11252.030124968574 3879.678261616992 7604.091458514949 9809.716929254793 10996.30874329212 3653.8324827124798 11260.71856837584 11802.37614189535 0.9573114466348633 1.193176476958269 0.9533698968487209 0.32872009966240173 0.6442847920701673 0.831164573244947 0.9317029563443668 0.3095844801744904 0.9541060573729074 1.0 13.526789722443826 -5.536217521819038 24.945879995456586 0.6922120941060164 1.0747513486162088 0.28815266691173114 0.23422841339471823 234.75297183233056 439028.13454436377 0.06172382117985292 0.10697895603919186 2.909259614055135e-06 5.536217521819038 0.38253925451019244 S(ph)PNREWEVLQPAPHQVITNLPEGVR ddPTM_PC-9_AZD4547_30min_R2 3 SPNREWEVLQPAPHQVITNLPEGVR 25 1 O75376-2;O75376;A0A088AWL3 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 S(1)PNREWEVLQPAPHQVITNLPEGVR;S(1)PNREWEVLQPAPHQVITNLPEGVR;S(1)PNREWEVLQPAPHQVITNLPEGVR 78.428 4.7091999999999996e-05 6421400.0 11686.66 11878.79 10966.0 14842.5 13288.400000000001 12538.699999999999 12627.4 17237.2 12278.5 12417.0 True False 15402.774782371122 15718.376565100825 10820.583674942882 11420.790939339076 11443.535034480476 11754.653106844973 13751.214137484849 14573.586811450925 12927.516442945436 11982.284609440656 1.2854622707121741 1.3118013031268312 0.9030484609268513 0.9531396817549145 0.9550378252127555 0.9810026626795081 1.1476287357296189 1.2162611126736735 1.0788857771547211 1.0 13.548615386213212 -5.24465744902991 24.84439451890656 1.0342172435375805 1.2986318528247176 0.584295250923886 0.09077175418559238 614.1927008420814 909262.8744129407 0.0267605674830367 0.0703670747949958 5.693017921585826e-06 5.24465744902991 0.2644146092871371 S(ph)PNREWEVLQPAPHQVITNLPEGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPNREWEVLQPAPHQVITNLPEGVR 25 1 O75376-2;O75376;A0A088AWL3 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 S(1)PNREWEVLQPAPHQVITNLPEGVR 71.425 0.00016514 2925200.0 3804.7 2897.9 4177.5 4659.2 7658.4 3627.2 4364.1 3708.7 4854.5 2458.7 True False 4448.760563749649 3185.5843604461006 4277.107443256971 4398.160129330209 6157.7914962844 3436.9832466793323 3950.700854652118 3611.3505546924625 4925.487878688289 2904.442846941507 1.5317087641901337 1.0967970548295163 1.4726085754315787 1.5142870289087098 2.1201283071446206 1.183353719732723 1.3602267501363856 1.2433884035608955 1.695846032527382 1.0 11.504045725728938 -10.760552770045953 4.226488075559927 0.9997333533435223 1.4601712866089325 0.20484465433690702 0.2765753408754574 203164690.52995086 264.5248928525201 545748.569992357 0.06823533084976124 1.7355903627759922e-11 10.760552770045953 0.46043793326541016 S(ph)PNREWEVLQPAPHQVITNLPEGVR ddPTM_PC-9_Lapatinib_30min_R1 4 SPNREWEVLQPAPHQVITNLPEGVR 25 1 O75376-2;O75376;A0A088AWL3 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 S(1)PNREWEVLQPAPHQVITNLPEGVR;S(1)PNREWEVLQPAPHQVITNLPEGVR;S(1)PNREWEVLQPAPHQVITNLPEGVR;S(1)PNREWEVLQPAPHQVITNLPEGVR 85.596 4.734700000000001e-06 9900600.0 27532.5 31054.0 33188.31 29220.809999999998 34572.17 36693.0 27728.5 32695.6 35053.95 26372.3 True False 27139.881501157884 30982.096370952055 30459.695262381403 31369.805845164607 32538.702932101394 35123.72592556069 29164.146053407487 34214.75693715604 31105.805016542028 30930.716916119134 0.877441074992164 1.0016611142564933 0.9847717188381022 1.0141958859290665 1.0519867037140764 1.135561326328535 0.9428861973195641 1.106174067350035 1.0056606544522624 1.0 14.916752652334637 -3.5967323888979 0.8129640605142999 1.0417385605568472 1.6276320416642618e-16 0.429818711563118 0.05320945121352189 13.020128874447593 1.5044698527555986 0.018234734407483723 19.036382887703294 0.00025308570234142976 3.5967323888979 -1.041738560556847 S(ph)PNVFR ddPTM_PC-9_Lapatinib_30min_R1 1 SPNVFR 6 0 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 S(1)PNVFR 91.318 0.03642 8187900.0 11015.0 9088.2 6781.0 6718.8 12588.0 7224.0 9111.1 9357.0 9183.0 6147.6 True False 10857.9240800964 9067.156831277349 6223.492355416963 7212.922965259759 11847.598588960209 6915.046359966492 9582.828177045321 9791.760379407906 8148.713838723043 7210.204468837903 1.5059107029521472 1.2575450350215571 0.8631506058274139 1.000377034581142 1.6431709586274372 0.9590638365184971 1.3290646913637143 1.3580419836534932 1.1301640437440192 1.0 12.81582445702635 -8.52869417214785 21.459493148925755 0.9999999681863405 1.2277985383918895 0.0948726817895501 0.2312770333714572 249.95831270378304 922380.8404298277 0.22506264071951532 0.058110923941585534 2.9600962167118866e-09 8.52869417214785 0.22779857020554894 S(ph)PPACSSSSSSLFSAVVAR ddPTM_PC-9_AZD4547_30min_R2 2 SPPACSSSSSSLFSAVVAR 19 0 P50548;P50548-2 P50548 ERF ETS domain-containing transcription factor ERF 1 S(1)PPACSSSSSSLFSAVVAR;S(1)PPACSSSSSSLFSAVVAR 115.53 7.3156e-05 4722400.0 2136.1 1528.58 2407.39 6478.6 5657.3 6715.0 2336.68 4803.299999999999 3538.99 2721.8999999999996 True False 2815.335366359847 2022.6635919888988 2375.4664356393178 4985.058863372219 4871.881547106225 6295.109988472806 2544.6399932510317 4061.060353853426 3726.053786408719 2626.607109481879 1.0718524884047833 0.7700670514014891 0.9043859003746849 1.897908082779676 1.8548192950209619 2.396669820068587 0.9687935375127283 1.5461240241044294 1.4185805608147142 1.0 11.358984701504841 -5.74743783683055 24.854854026103382 1.6256288378989474 0.9008979391778628 0.36029085729602217 0.40491444135801047 229.41495427264437 407242.50744174677 0.11246236525894036 0.19354102140563814 1.7888015526605807e-06 5.74743783683055 -0.7247308987210846 S(ph)PPACSSSSSSLFSAVVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPPACSSSSSSLFSAVVAR 19 0 P50548;P50548-2 P50548 ERF ETS domain-containing transcription factor ERF 1 S(1)PPACSSSSSSLFSAVVAR 82.774 0.015877000000000002 0.0 6816.8 5766.5 6190.8 8357.6 9767.0 10214.0 11151.0 9470.5 7212.5 6820.3 True False 7970.749602062874 6338.960010529149 6338.412150739746 7889.350767704788 7853.226462996149 9678.359859280632 10094.696553751237 9221.909409824197 7317.969167790565 8056.766400534907 0.9893236573836469 0.7867871172370458 0.7867191172774879 0.9792204931225257 0.9747367706322918 1.201271003542819 1.2529464119849654 1.1446167049366025 0.9083010235104629 1.0 12.97598521101328 -6.287210965849009 1.9819589684159333 1.1154711752765756 0.8550983530021862 0.4500958921256558 0.11145301777122509 0.28464376714231293 2.1971339722590124 0.03992771964153007 0.05106864179264328 5.161655722544264e-07 6.287210965849009 -0.2603728222743894 S(ph)PPACSSSSSSLFSAVVAR ddPTM_PC-9_Lapatinib_30min_R1 2 SPPACSSSSSSLFSAVVAR 19 0 P50548;P50548-2 P50548 ERF ETS domain-containing transcription factor ERF 1 S(0.998)PPACS(0.001)S(0.001)SSSSLFSAVVAR;S(1)PPACSSSSSSLFSAVVAR 86.738 0.0012174000000000002 4942300.0 3981.2999999999997 3657.23 3803.84 4214.8 4487.7 5767.6 3530.95 2877.8 4028.7 3951.44 True False 3924.525931918997 3648.761908634542 3491.1029584470216 4524.770452160628 4223.742309157668 5520.9331929322725 3713.765313928959 3011.5130939254104 3574.945381908255 4634.441139037161 0.8468175156787828 0.7873143274816948 0.7532953496896335 0.9763357255845271 0.9113811530758122 1.1912834853868242 0.8013404858348295 0.649811488284664 0.7713865112657308 1.0 12.17817966136598 -11.838748613641718 2.1776776944849185 1.6971042536692875 0.8569900094417129 0.08769625099465395 0.14071690226213868 13542083.423771381 1611873.362989796 46546818.28678676 0.039904377751186236 1.4496107011992484e-12 11.838748613641718 -0.8401142442275746 S(ph)PPADAIPK ddPTM_PC-9_AZD4547_30min_R2 6 SPPADAIPK 9 0 P18754-2;M0R1Q8;C9JRH2;C9J3R0;C9JMJ4;C9JQZ4;C9JW69;P18754 P18754-2 RCC1 Regulator of chromosome condensation 1 S(1)PPADAIPK;S(1)PPADAIPK;S(1)PPADAIPK;S(1)PPADAIPK;S(1)PPADAIPK;S(1)PPADAIPK 95.48299999999999 0.005411600000000001 586069900.0 452903.0 383779.0 586098.0 744033.0 622563.0 564349.0 573619.0 664608.0 548266.0 601346.0 True False 596916.7330323835 507828.0565426129 578325.95757037 572507.6870452604 536130.8736696105 529060.1678160296 624669.9797527546 561908.104772515 577246.2214527772 580293.0595754782 1.0286470313276994 0.8751234366203205 0.9966101576218278 0.9865837228246134 0.9238967532402073 0.9117120377125849 1.0764732912879242 0.9683178102863871 0.9947494837781965 1.0 19.146422148501408 -7.241342142220111 24.998700485152145 1.007244979375768 0.9522697072868251 0.23933309769449262 0.048882547615938264 1220.5346493436657 1518209.956612219 0.01820477381540894 0.014086395168812984 5.7366434472767024e-08 7.241342142220111 -0.05497527208894293 S(ph)PPADAIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SPPADAIPK 9 0 P18754-2;M0R1Q8;C9JRH2;C9J3R0;C9JMJ4;C9JQZ4;C9JW69;P18754 P18754-2 RCC1 Regulator of chromosome condensation 1 S(1)PPADAIPK;S(1)PPADAIPK;S(1)PPADAIPK;S(1)PPADAIPK;S(1)PPADAIPK 105.4 0.0026389 369970000.0 347498.0 428099.0 409725.0 408179.0 464571.0 378816.0 424845.0 379743.0 334399.0 271442.0 True False 406322.5480016501 470597.83951227233 419494.3978907164 385310.0539641733 373541.64750082814 358950.22209254524 384600.6059885617 369775.14862096665 339288.952754245 320652.28586631076 1.2671749615128511 1.4676266481021696 1.3082532586891202 1.2016444945127267 1.164943036322431 1.119437589920073 1.199431979564658 1.1531966710355424 1.0581211103410142 1.0 18.290650166334913 -5.0903835270443665 0.23266905197027904 0.99490294187637 1.6627218159393027 0.7250921264769647 0.06580866752760207 5.227072946184078 0.2826926549408754 0.11716468269692568 1.007434809490826 8.1211301942291e-06 5.0903835270443665 0.6678188740629327 S(ph)PPADAIPK ddPTM_PC-9_Lapatinib_30min_R1 3 SPPADAIPK 9 0 P18754-2;M0R1Q8;C9JRH2;C9J3R0;C9JMJ4;C9JQZ4;C9JW69;P18754 P18754-2 RCC1 Regulator of chromosome condensation 1 S(1)PPADAIPK;S(1)PPADAIPK;S(1)PPADAIPK 96.171 0.0051903999999999995 446872000.0 313499.0 489900.0 571150.0 545130.0 584410.0 594970.0 474240.0 498400.0 587590.0 490810.0 True False 309028.44677132485 488765.66664936533 524192.25170275755 585220.6787003719 550036.1527942668 569524.5200428113 498793.8267258585 521557.48349865264 521409.42660299153 575645.8545367835 0.5368377872190132 0.8490735454747089 0.9106158718446254 1.016633185296354 0.9555113590401435 0.9893661450947162 0.8664942564855833 0.9060388073468274 0.9057816059885717 1.0 19.134821992640653 -4.668501277508327 1.9795435988488073 0.9428430936959669 0.32621714631748555 0.8793168910467511 0.04530159889006302 0.3696283958139166 1.2223235932949867 0.012906482281462643 0.46195952398555873 2.1453528050974772e-05 4.668501277508327 -0.6166259473784813 S(ph)PPAPGLQPMR ddPTM_PC-9_AZD4547_30min_R2 1 SPPAPGLQPMR 11 0 P15408;P15408-3;P15408-2;C9JCN8 P15408 FOSL2 Fos-related antigen 2 1 S(1)PPAPGLQPMR 71.085 0.026955 27508000.0 14991.0 15934.0 17649.0 36008.0 29686.0 21672.0 18301.0 25405.0 19764.0 17986.0 True False 19757.82616782943 21084.353893647138 17414.962728348266 27706.911918054317 25564.611317659554 20316.846414025702 19929.753546265274 21479.240998822945 20808.68469099431 17356.31561451233 1.1383652271977065 1.2147943354992716 1.0033790071083346 1.5963590737476236 1.472928465087598 1.1705736900196695 1.148270980368736 1.2375461172683027 1.1989114022330472 1.0 14.08317310562613 -6.947174820993341 24.998918347659114 1.1650387439223557 1.2867757557766475 0.13926992894923884 0.1649057337912049 242.01786374445527 114531.10543620931 0.06244398052133726 0.055070406566530124 1.1293412179074279e-07 6.947174820993341 0.12173701185429175 S(ph)PPAPGLQPMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPPAPGLQPMR 11 0 P15408;P15408-3;P15408-2;C9JCN8 P15408 FOSL2 Fos-related antigen 2 1 S(1)PPAPGLQPMR 66.32600000000001 0.037406 62977000.0 26969.0 24214.0 24181.0 28018.0 31995.0 27962.0 26463.0 29934.0 25824.0 26763.0 True False 31534.31903796997 26617.805895248926 24757.56674695316 26448.24229558159 25725.809428029264 26495.623495712283 23956.23306447125 29148.26421769467 26201.627145791837 31614.92004420855 0.9974505389820416 0.8419381057433662 0.7830975600233546 0.8365747013940834 0.8137236909679265 0.838073398846566 0.757750866710154 0.9219781096056974 0.8287741075780972 1.0 14.948317950414523 -10.937922800668634 8.398514290093972 1.000001923158085 0.8426829315542823 0.3332689668150923 0.06488128832181553 2.303075652671701e-06 1.6041564139797226e-07 0.06192569671084107 0.015019004060001083 1.1536583116238696e-11 10.937922800668634 -0.1573189916038027 S(ph)PPAPPPYK ddPTM_PC-9_AZD4547_30min_R2 1 SPPAPPPYK 9 0 A0A669KBI7;Q9UMN6 A0A669KBI7 KMT2B Histone-lysine N-methyltransferase 2B 1 S(1)PPAPPPYK 76.465 0.024475999999999998 4966600.0 22936.0 26713.0 29778.0 30671.0 33012.0 36616.0 28222.0 40018.0 31941.0 25361.0 True False 30229.17090156335 35347.4548488136 29383.124263400434 23600.27481222629 28428.853628598554 34326.3957316337 30733.703326741637 33834.13762215693 33629.33605115611 24473.119109287625 1.235198944873818 1.4443379567175452 1.2006284990559069 0.9643345707932223 1.1616358953530248 1.4026162982472765 1.2558147242898066 1.3825020615911916 1.37413363212839 1.0 14.578910364772657 -6.739700976616809 24.96739011889641 1.3052198590224313 1.2015393624342308 0.057483249194458685 0.1528892199460048 621.3002282663955 713585.748319613 0.05237756313191042 0.05233352874574715 1.8209542028220986e-07 6.739700976616809 -0.10368049658820055 S(ph)PPEALVQGR ddPTM_PC-9_AZD4547_30min_R2 1 SPPEALVQGR 10 0 Q9UHB6;Q9UHB6-4;F8VRN8 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 S(1)PPEALVQGR 83.081 0.014033000000000002 8248600.0 3620.6 4305.3 25839.0 27261.0 18215.0 17092.0 6300.1 22337.0 20052.0 6763.9 True False 4771.8754868416545 5696.904030269801 25496.357977097312 20976.39762825147 15686.161663786585 16023.234538045755 6860.796695089114 18885.329903196536 21111.907783030652 6527.097919770927 0.7310868544483438 0.8728081147692877 3.9062318798477786 3.2137403002202323 2.403236761053081 2.454878835126791 1.0511251369934862 2.8933731553179043 3.2345014648978316 1.0 12.672225967492187 -5.143753902569346 8.879403604884086 2.5521780288504585 0.7714461005094473 0.38456855159340464 0.868965894150119 0.32027477915351726 22.299812678011786 0.22475068030133194 0.5988417596122957 7.18201152047058e-06 5.143753902569346 -1.7807319283410112 S(ph)PPEALVQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPPEALVQGR 10 0 Q9UHB6;Q9UHB6-4;F8VRN8 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 S(1)PPEALVQGR 72.289 0.03095 4994400.0 2129.5 4111.0 9582.7 2536.0 4323.8 9116.4 3891.9 3303.5 2530.9 3603.5 True False 2489.982290457822 4519.112911347501 9811.187910592133 2393.9161418229323 3476.582428658009 8638.319935495001 3523.231057084067 3216.786625347578 2567.90962450761 4256.786024709696 0.5849441987461969 1.0616255750500625 2.3048346460546454 0.5623764332824769 0.8167153360486578 2.0293056511066037 0.8276739861088845 0.7556843606126423 0.603250811669054 1.0 12.055548856846828 -7.4898796366954405 24.902686982002148 0.7660158079416931 1.2367473863382827 0.13110400242740183 0.5419432564521612 1227.6118428179766 926416.471194988 0.23083439141790313 0.15549491452011197 3.236833522890475e-08 7.4898796366954405 0.47073157839658963 S(ph)PPEALVQGR ddPTM_PC-9_Lapatinib_30min_R1 2 SPPEALVQGR 10 0 Q9UHB6;Q9UHB6-4;F8VRN8 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 S(1)PPEALVQGR;S(1)PPEALVQGR 121.29 0.00063498 12765500.0 3055.8 2590.2 5788.2 5533.1 6658.799999999999 5398.3 3115.7 3863.8 7237.0 0.0 True False 3012.2237316349137 2584.2025510414146 5312.316539098137 5940.022631880514 6267.142475704499 5167.427293051929 3277.015700762816 4043.3262534953797 6421.8928510115065 0.0 0.0 S(ph)PPEEPPDFCCPK ddPTM_PC-9_AZD4547_30min_R2 1 SPPEEPPDFCCPK 13 0 A0A087X0G7;A0A087WUW6;A0A087X1B1;Q9Y6K9-3;Q9Y6K9;Q9Y6K9-2 A0A087X0G7 IKBKG NF-kappa-B essential modulator 1 S(1)PPEEPPDFCCPK 159.5 0.00026844 9061200.0 10284.0 8458.4 12074.0 18826.0 18129.0 17299.0 12074.0 12208.0 12056.0 12268.0 True False 13554.09807951157 11192.412386972821 11913.890870988544 14485.956558800559 15612.101279318531 16217.290795322575 13148.56260956269 10321.534111931926 12693.255547188188 11838.501054088581 1.144916743900655 0.9454247911822734 1.0063681893979242 1.2236309725881762 1.3187565898747533 1.3698770411243677 1.110661100547156 0.8718615697016177 1.0722012431467753 1.0 13.531198803528785 -7.556419650937039 10.977883517781002 0.9812362582195079 1.166719190382506 0.29934875238794967 0.127818918520784 0.8415738185806939 269.7765048972199 0.06881197714969031 0.03977719536699279 2.7770285781785306e-08 7.556419650937039 0.18548293216299816 S(ph)PPEEPPDFCCPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPPEEPPDFCCPK 13 0 A0A087X0G7;A0A087WUW6;A0A087X1B1;Q9Y6K9-3;Q9Y6K9;Q9Y6K9-2 A0A087X0G7 IKBKG NF-kappa-B essential modulator 1 S(1)PPEEPPDFCCPK;S(1)PPEEPPDFCCPK 86.738 0.027351999999999998 6822700.0 15078.2 14396.5 16742.0 15547.7 17363.8 19680.1 15889.0 14130.900000000001 16624.6 13124.7 True False 17630.641451975174 15825.689376846083 17141.192774388564 14676.612775323494 13961.488037081246 18648.040911163967 14383.87889360177 13759.97884792617 16867.70332434676 15504.104214931966 1.1371596325439521 1.0207419375834947 1.1055906575937438 0.9466275878865986 0.9005027213139454 1.2027809315938476 0.92774653047989 0.8875055699557262 1.0879508477569129 1.0 13.920362552903486 -5.7537594141167165 24.9863638115901 0.9907449287834251 1.0811218735180723 0.17668884485449865 0.09305685054156694 326.27088235001315 1061492.938364609 0.02549763075324926 0.04311146524976615 1.7629523977549007e-06 5.7537594141167165 0.09037694473464719 S(ph)PPEEPPDFCCPK ddPTM_PC-9_Lapatinib_30min_R1 2 SPPEEPPDFCCPK 13 0 A0A087X0G7;A0A087WUW6;A0A087X1B1;Q9Y6K9-3;Q9Y6K9;Q9Y6K9-2 A0A087X0G7 IKBKG NF-kappa-B essential modulator 1 S(1)PPEEPPDFCCPK;S(1)PPEEPPDFCCPK 182.37 7.0039e-05 18783700.0 34582.0 46229.0 51971.0 47760.0 50428.0 47877.0 38618.0 40340.0 46095.0 37435.0 True False 34088.854338437915 46121.95959080129 47698.14499386149 51272.42972268949 47461.92418526259 45829.41231673808 40617.45108067479 42214.34366841029 40903.295698131195 43905.58987099795 0.7764126262418233 1.0504803540122205 1.0863797783837252 1.167788199027426 1.0809995794319984 1.0438172554199283 0.9251088802135613 0.9614799343874704 0.9316193181394896 1.0 15.422117008735567 -7.249717180963945 22.710177008298682 0.9513420310625017 1.0456037149843256 0.13348290086648018 0.0968932190723131 405.41221581872776 785432.6390235506 0.03886771130569622 0.02979249286458809 5.627076495031733e-08 7.249717180963945 0.09426168392182388 S(ph)PPEFQ ddPTM_PC-9_Lapatinib_30min_R1 1 SPPEFQ 6 0 Q96GX2 Q96GX2 ATXN7L3B Putative ataxin-7-like protein 3B 1 S(1)PPEFQ 85.265 0.041235 0.0 13869.0 12760.0 8535.8 8480.9 7909.8 8982.4 10776.0 9474.8 7087.8 7693.7 True False 13671.225516736897 12730.455003972056 7834.019473140848 9104.61367745304 7444.561115265133 8598.243690997097 11333.928552627045 9915.033797457947 6289.49732615716 9023.545793789152 1.5150613549439416 1.4108040558440282 0.8681752885360158 1.0089840385937519 0.8250150534382146 0.9528675187657619 1.2560393454675118 1.098795753248396 0.6970095204133813 1.0 13.139478735206898 -5.184248249625862 5.144657854528016 0.9739681347286029 1.4832615719373103 0.6548491813480597 0.14527066982455233 0.1361599308004047 6.422868955229535 0.03876276764708587 0.10816459833121132 6.542620805584981e-06 5.184248249625862 0.5092934372087075 S(ph)PPEGDTTLFLSR ddPTM_PC-9_AZD4547_30min_R2 4 SPPEGDTTLFLSR 13 0 Q9BTC0;Q9BTC0-1 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 S(1)PPEGDTTLFLSR;S(1)PPEGDTTLFLSR;S(1)PPEGDTTLFLSR;S(1)PPEGDTTLFLSR 106.54 0.0011068 25275500.0 3064.94 4630.199999999999 8443.74 7482.6 6295.1 4958.219999999999 5484.030000000001 6473.8 5386.5 4685.8 True False 4039.527165287651 6126.82160150401 8331.77049055829 5757.602175017588 5421.134026335601 4648.181719589821 5972.0980460261835 5473.4229631245835 5671.219393242304 4521.7515682465155 0.8933545119229392 1.354966434805688 1.842598020879165 1.2733123631668959 1.1989013426577648 1.0279604373294515 1.3207488195425332 1.2104652103315607 1.2542085312841589 1.0 12.142666015118536 -5.994402172572051 24.99202404597516 1.1849200150216435 1.3953027465791599 0.11949634020804611 0.2316424462116155 310.0710514327032 1384318.7934953861 0.06724253837502736 0.09940036995809295 1.0129729013180549e-06 5.994402172572051 0.2103827315575164 S(ph)PPEGDTTLFLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPPEGDTTLFLSR 13 0 Q9BTC0;Q9BTC0-1 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 S(1)PPEGDTTLFLSR;S(1)PPEGDTTLFLSR;S(1)PPEGDTTLFLSR;S(1)PPEGDTTLFLSR 96.866 0.0031555999999999997 24571800.0 9720.6 15574.119999999999 4103.08 8238.76 6081.469999999999 4005.1000000000004 5308.200000000001 5624.240000000001 5363.4 5561.9800000000005 True False 11366.105589398592 17120.21570782664 4200.912988217551 7777.168987620308 4889.849609697675 3795.065505424406 4805.368867960032 5476.609659374862 5441.829578444077 6570.322945390542 1.729915817512831 2.605688616849108 0.6393769413061701 1.1836813886106523 0.7442327645596454 0.5776071491412552 0.731374836199075 0.833537362606661 0.8282438509756711 1.0 12.681748568491724 -5.268365156090082 24.99962816496982 0.8101641238966856 2.167802240879074 0.8169707124210033 0.2556797073472419 173.72468484850853 627086.9187941854 0.06327675970859946 0.13643406670999572 5.390571910315465e-06 5.268365156090082 1.3576381169823883 S(ph)PPEGDTTLFLSR ddPTM_PC-9_Lapatinib_30min_R1 4 SPPEGDTTLFLSR 13 0 Q9BTC0;Q9BTC0-1 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 S(1)PPEGDTTLFLSR;S(1)PPEGDTTLFLSR;S(1)PPEGDTTLFLSR;S(1)PPEGDTTLFLSR 130.61 7.8388e-05 27128800.0 5218.67 4095.88 8054.5199999999995 9187.04 4798.59 6103.57 4645.4400000000005 2076.61 4793.86 2966.41 True False 5144.250808813129 4086.3962415101178 7392.3084569463235 9862.685568667024 4516.346370590923 5842.534539216594 4885.958152887513 2173.0968816375193 4253.925005216253 3479.150016007135 1.4785941351034226 1.1745386725806932 2.1247455335168746 2.834797442849558 1.298117744222519 1.679299401387069 1.4043539745075175 0.624605685767895 1.2226908830158156 1.0 11.764519171922121 -7.373828671609551 1.8481373083724508 0.9407946311650712 1.8114967299680043 0.37623959193196876 0.4639702036537398 0.40414801357808455 2.690174429890914 0.2812512622172527 0.160226131262418 4.2283538916625665e-08 7.373828671609551 0.870702098802933 S(ph)PPETAAPVEDMAR ddPTM_PC-9_AZD4547_30min_R2 1 SPPETAAPVEDMAR 14 0 Q9Y3L3;A0A2R8Y5V0;Q6ZT62-2;Q6ZT62;A0A3B3IU28 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 S(0.999)PPET(0.001)AAPVEDMAR 96.37100000000001 0.0026121 7556400.0 2195.3 4966.7 6171.5 3210.9 9394.6 6848.3 5736.7 9589.0 6079.8 4789.4 True False 2893.3597349233523 6572.088645887861 6089.661877613537 2470.6766129104826 8090.321952600028 6420.074718400346 6247.255186539531 8107.240383299085 6401.165815842298 4621.724563779904 0.6260346532976861 1.421999202936672 1.3176167886199328 0.534578938838758 1.7504985078520803 1.3891080331168957 1.3517151661305788 1.7541591393902825 1.3850167242781486 1.0 12.174215568199907 -6.280188541989782 24.992331227688993 1.4693237334067537 1.0314502631158966 0.32046928721813606 0.3245754417457618 1021.4756583278091 1361607.0387822853 0.09817937643761256 0.11151054123195449 5.24579672949586e-07 6.280188541989782 -0.4378734702908571 S(ph)PPETAAPVEDMAR ddPTM_PC-9_Lapatinib_30min_R1 2 SPPETAAPVEDMAR 14 0 Q9Y3L3;A0A2R8Y5V0;Q6ZT62-2;Q6ZT62;A0A3B3IU28 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 S(1)PPETAAPVEDMAR;S(1)PPETAAPVEDMAR 173.25 0.00014681 49330000.0 20573.0 27649.0 24200.0 20455.0 27878.15 24798.0 35222.48 27067.6 11194.0 22213.0 True False 20279.625247373853 27584.980439249495 22210.36941470145 21959.328935879683 26238.41202755172 23737.4473469614 37046.127669481735 28325.25951113195 9933.213841954233 26052.48745303801 0.7784141642493727 1.058823288523752 0.8525239463117551 0.8428879958377633 1.0071365382998017 0.911139383129934 1.421980443758423 1.087238197972106 0.38127698400622045 1.0 14.669133505022065 -4.7404055862708825 23.809446056499404 0.9628726991048607 0.7784129252937823 0.040771869216785106 0.24623038997236993 3269.7210293906483 3700845.140764423 0.06171826241358092 2.493269631677656 1.818002238908207e-05 4.7404055862708825 -0.18445977381107848 S(ph)PPGAAASAAAKPPPLSAK ddPTM_PC-9_AZD4547_30min_R2 3 SPPGAAASAAAKPPPLSAK 19 1 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 S(0.996)PPGAAAS(0.004)AAAKPPPLSAK;S(0.982)PPGAAAS(0.018)AAAKPPPLSAK;S(0.997)PPGAAAS(0.003)AAAKPPPLSAK 89.846 0.00048713 423811000.0 237145.0 223124.0 264809.0 274724.0 267671.0 297701.0 290408.0 306335.0 282932.0 269130.0 True False 312552.17707757384 295244.46957236883 261297.45963687313 211390.62624348918 230509.50198778 279085.7094085389 316253.7494051585 258997.96462800304 297887.2079028743 259707.8406167961 1.2034760919627012 1.136833100114246 1.0061207971861832 0.8139555037747208 0.8875723637774232 1.0746141077054936 1.2177289243715863 0.9972666362821118 1.14700891276676 1.0 17.986530044279924 -9.513531180613208 15.83801396577702 0.999999980564485 1.0467006102069247 0.013562866258609585 0.12505060693589506 0.0 0.0 0.13305241703347315 0.032269951127808255 3.0652705973110867e-10 9.513531180613208 0.046700629642439706 S(ph)PPGAAASAAAKPPPLSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPPGAAASAAAKPPPLSAK 19 1 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 S(1)PPGAAASAAAKPPPLSAK;S(0.989)PPGAAAS(0.011)AAAKPPPLSAK 96.14299999999999 0.00031774 293470000.0 389500.0 479810.0 455100.0 451030.0 446630.0 411930.0 405110.0 337730.0 378460.0 309240.0 True False 455434.6570243357 527442.3658461784 465951.3099763612 425760.25135898974 359116.05766028195 390327.6656386793 366735.04805758706 328864.94535451476 383994.26152402395 365302.764057507 1.2467320311670018 1.443849917771624 1.275520898886519 1.1654996710946468 0.9830641675729256 1.0685045503166049 1.003920813475845 0.900253098831587 1.051167139440463 1.0 18.478733144306936 -5.939823904366564 1.8881786318572604 0.9967178580126367 1.3484329313651995 0.8402082311157507 0.06309341611801285 0.11844153548709095 0.8556709319416457 0.01975289798910396 0.0336320961340418 1.1486192636905862e-06 5.939823904366564 0.3517150733525628 S(ph)PPGAAASAAAKPPPLSAK ddPTM_PC-9_Lapatinib_30min_R1 3 SPPGAAASAAAKPPPLSAK 19 1 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 S(0.973)PPGAAAS(0.027)AAAKPPPLSAK;S(0.998)PPGAAAS(0.002)AAAKPPPLSAK;S(1)PPGAAASAAAKPPPLSAK 109.28 0.00057268 294620000.0 603047.0 756298.0 781529.0 715346.0 771793.0 796588.0 711350.0 683209.0 714666.0 595454.0 True False 594447.439194724 754546.8384478122 717274.7024091802 767954.9311643011 726397.653143419 762519.7881773249 748180.2223377177 714953.3843170779 634172.7893133876 698377.4305074173 0.851183633988313 1.0804284409643423 1.0270588238913059 1.0996273613915775 1.040121890273062 1.0918448318458744 1.0713121439135216 1.0237349505948625 0.9080659849683561 1.0 19.41364741052164 -8.091970415943091 6.226001447611265 0.9554255149192967 1.043528430745398 0.17652299161133866 0.07010310232607264 0.3728610606998987 20.603128110353754 0.046765055546137954 0.0173689902131457 8.09151016513304e-09 8.091970415943091 0.0881029158261013 S(ph)PPGSGASTPVGPWDQAVQR ddPTM_PC-9_AZD4547_30min_R2 4 SPPGSGASTPVGPWDQAVQR 20 0 Q8TE77;C9JUG3;Q8TE77-4;Q8TE77-2 Q8TE77 SSH3 Protein phosphatase Slingshot homolog 3 1 S(0.999)PPGS(0.001)GASTPVGPWDQAVQR;S(1)PPGSGASTPVGPWDQAVQR;S(0.999)PPGS(0.001)GASTPVGPWDQAVQR;S(1)PPGSGASTPVGPWDQAVQR 176.85 2.1645999999999997e-09 159501000.0 10870.7 5700.299999999999 16142.800000000001 17095.9 17525.6 9247.5 7807.6 14641.5 13969.6 13871.8 True False 14327.356475393459 7542.81049955797 15928.735924481856 13154.704384022025 15092.472953876377 8669.252363127664 8502.461274674642 12378.992603198834 14708.004536496366 13386.152504247315 1.0703117621622424 0.5634786020228515 1.1899413158058525 0.9827098846997407 1.1274690729160348 0.6476283876473827 0.6351684154186114 0.9247610617965903 1.0987477194682818 1.0 13.708453735232144 -6.750078092512108 24.998241647837823 0.8424278565818608 0.9743255964903089 0.07955432549159724 0.20645410814579462 610.6789274187875 1343674.4903393772 0.07057809652497006 0.0699792479959941 1.7779596780887438e-07 6.750078092512108 0.1318977399084481 S(ph)PPGSGASTPVGPWDQAVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPPGSGASTPVGPWDQAVQR 20 0 Q8TE77;C9JUG3;Q8TE77-4;Q8TE77-2 Q8TE77 SSH3 Protein phosphatase Slingshot homolog 3 1 S(1)PPGSGASTPVGPWDQAVQR;S(1)PPGSGASTPVGPWDQAVQR;S(0.993)PPGS(0.005)GAS(0.001)T(0.001)PVGPWDQAVQR 166.52 4.1828e-08 97146000.0 26522.3 29090.1 33135.6 39085.7 42193.0 32912.7 40212.7 26447.8 26517.5 22779.1 True False 31012.001550697125 31977.97287822666 33925.678371462775 36895.85494654912 33925.58453498481 31186.700072502998 36403.46194126378 25753.57327376046 26905.268271318717 26908.770510743623 1.1524867529088794 1.1883847634532059 1.2607665726651307 1.3711460704537968 1.2607630854571987 1.158979005006987 1.3528474638679346 0.9570698617938735 0.9998698476608767 1.0 14.715788853821156 -7.7718219980971535 24.999847806528035 0.9838522853169043 1.249083102847144 0.7513984841017725 0.06950388332610254 108.27621942572458 260709.2345149915 0.039034816117153176 0.01907224456899719 1.6911339254249394e-08 7.7718219980971535 0.2652308175302398 S(ph)PPGSGASTPVGPWDQAVQR ddPTM_PC-9_Lapatinib_30min_R1 4 SPPGSGASTPVGPWDQAVQR 20 0 Q8TE77;C9JUG3;Q8TE77-4;Q8TE77-2 Q8TE77 SSH3 Protein phosphatase Slingshot homolog 3 1 S(1)PPGSGASTPVGPWDQAVQR;S(1)PPGSGASTPVGPWDQAVQR;S(1)PPGSGASTPVGPWDQAVQR;S(1)PPGSGASTPVGPWDQAVQR 210.2 1.6275999999999998e-21 171061000.0 11948.099999999999 12986.8 13107.7 8000.76 12296.3 12288.8 7362.999999999999 4313.900000000001 14638.800000000001 11271.800000000001 True False 11777.717902986804 12956.72986250662 12030.035503185203 8589.162580152959 11573.055809455947 11763.236670591952 7744.22011256431 4514.3395426662155 12990.024190602084 13220.1156112706 0.8908937144956507 0.9800768952020786 0.9099795990383918 0.6497040444056635 0.8754126022611726 0.8897983207169075 0.5857906496643719 0.3414750426855259 0.9825953548793208 1.0 13.690447172966723 -7.24973049313521 24.423110994611363 0.6725881810260307 0.8637622219995158 0.08136972929256447 0.19583372132871155 959.8159645243169 2002045.6532092239 0.0741857695301948 0.05695319588164688 5.6269040142356584e-08 7.24973049313521 0.19117404097348512 S(ph)PPITPNWR ddPTM_PC-9_Lapatinib_30min_R1 1 SPPITPNWR 9 0 J3KN34;P26045-2;P26045 J3KN34 PTPN3 Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 3 1 S(1)PPITPNWR 80.102 0.019178 3434000.0 3196.4 3534.5 4005.6 1418.3 942.47 3046.8 3535.2 1035.8 3159.3 1687.5 True False 3150.818749852032 3526.3160824090323 3676.275030063145 1522.606513310103 887.0357675673123 2916.495466437697 3718.235358133551 1083.9270493738063 2803.466365096124 1979.1821265475896 1.591980196056136 1.7817036820963035 1.8574718216942976 0.7693109658210587 0.448182992191135 1.4735861987219545 1.8786726639551359 0.5476641259208255 1.416477204140068 1.0 10.950688661563548 -5.750565473158066 24.99986585824864 1.0812411754322275 1.747517255150992 0.3510459760353737 0.4158164908884183 256.5155680461983 589741.6361363756 0.11890182921508466 0.20338285180263535 1.775965507953906e-06 5.750565473158066 0.6662760797187646 S(ph)PPKEYIDEEGVR ddPTM_PC-9_AZD4547_30min_R2 1 SPPKEYIDEEGVR 13 1 H7BXF5;A0A2R8YDB8;Q9H0E3;Q9H0E3-3;Q9H0E3-2 H7BXF5 SAP130 Histone deacetylase complex subunit SAP130 1 S(0.999)PPKEY(0.001)IDEEGVR 57.52 0.032583999999999995 9407200.0 17060.0 21796.0 20739.0 23268.0 29192.0 21727.0 29763.0 22515.0 19519.0 18316.0 True False 22484.725129955987 28841.130755989274 20463.987309378117 17903.922087016443 25139.19469059887 20368.40725533116 32411.84934142907 19035.82409322963 20550.73449117173 17674.7624149565 1.2721373335649062 1.6317690772229967 1.1578083387452696 1.0129653608167328 1.4223215056812257 1.1524006250910213 1.833792646287678 1.0770059391079219 1.1627163075064342 1.0 14.109403201935312 S(ph)PPKEYIDEEGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPPKEYIDEEGVR 13 1 H7BXF5;A0A2R8YDB8;Q9H0E3;Q9H0E3-3;Q9H0E3-2 H7BXF5 SAP130 Histone deacetylase complex subunit SAP130 1 S(0.953)PPKEY(0.047)IDEEGVR;S(1)PPKEYIDEEGVR 63.602 0.021138 18935100.0 31796.0 50578.0 38046.0 40719.0 61737.0 36783.0 48085.0 40138.0 31598.0 34082.0 True False 37178.434800374205 55599.04958164288 38953.160930258506 38437.64644277916 49640.07803276269 34854.03472722925 43530.04069474739 39084.42002972637 32060.060972457006 40260.796807036466 0.9234401141776819 1.3809724096649203 0.9675208644517085 0.9547164857914915 1.2329631296340113 0.8657065307047708 1.0812016687940849 0.9707810855570425 0.796309648964866 1.0 15.297088104669719 -7.084859158787037 0.734142483732281 0.9162409866168277 1.1035068227679437 0.1395594008441724 0.15307822158951587 1.2906907851492215 1.4285036425390385 0.11957894932179068 0.08751017415995851 8.225093455576456e-08 7.084859158787037 0.18726583615111592 S(ph)PPKVPIVIQDDSLPAGPPPQIR ddPTM_PC-9_AZD4547_30min_R2 2 SPPKVPIVIQDDSLPAGPPPQIR 23 1 Q7Z422-4;Q7Z422-5;Q7Z422;Q7Z422-2;Q7Z422-3 Q7Z422-4 SZRD1 SUZ domain-containing protein 1 1 S(1)PPKVPIVIQDDSLPAGPPPQIR;S(0.997)PPKVPIVIQDDS(0.003)LPAGPPPQIR 106.36 1.0111e-06 58835000.0 19014.8 19472.4 18812.8 18694.300000000003 20248.6 21298.0 20992.5 20728.9 23369.0 21462.0 True False 25061.1108675901 25766.47249646383 18563.32997993485 14384.617959055859 17437.431406277738 19966.23269314875 22860.79183213888 17525.724807734736 24604.237631240947 20710.621912524377 1.2100607588435017 1.2441187234885505 0.896319292503187 0.6945526802532674 0.8419559528404487 0.9640576114749374 1.1038196693800983 0.8462191469555228 1.1880009077063 1.0 14.338083255978146 -5.2594122562926175 24.87894973277539 0.93054931205085 1.2270897717575242 0.4250869808398211 0.13215770549200218 152.23939914403073 1868401.6741766678 0.03562613967590969 0.08512915885274613 5.502850874226533e-06 5.2594122562926175 0.2965404597066742 S(ph)PPKVPIVIQDDSLPAGPPPQIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SPPKVPIVIQDDSLPAGPPPQIR 23 1 Q7Z422-4;Q7Z422-5;Q7Z422;Q7Z422-2;Q7Z422-3 Q7Z422-4 SZRD1 SUZ domain-containing protein 1 1 S(1)PPKVPIVIQDDSLPAGPPPQIR;S(1)PPKVPIVIQDDSLPAGPPPQIR;S(1)PPKVPIVIQDDSLPAGPPPQIR;S(1)PPKVPIVIQDDSLPAGPPPQIR;S(1)PPKVPIVIQDDSLPAGPPPQIR 156.15 1.6057e-08 35272900.0 73857.5 107555.7 79801.8 94956.7 94627.6 73139.4 94579.8 75834.7 65039.799999999996 60891.799999999996 True False 86360.1159978814 118233.11908514162 81704.57756201173 89636.58395277511 76086.00106991053 69303.84110944495 85620.5166455458 73844.11947850655 65990.88403178709 71931.0013207763 1.200596605248945 1.6437018380695276 1.1358743248637702 1.2461467560147086 1.0577636856548822 0.9634766628700813 1.1903145385634366 1.0265965734190006 0.9174192325990396 1.0 16.134326066936104 -5.8055052658599475 1.3128851577246068 1.0293987226938675 1.4115029252645928 0.5205175893065348 0.13693931734711864 0.34909260332152003 1.205990707660886 0.045600660790073265 0.1070627583574341 1.5649293441997257e-06 5.8055052658599475 0.3821042025707253 S(ph)PPKVPIVIQDDSLPAGPPPQIR ddPTM_PC-9_Lapatinib_30min_R1 3 SPPKVPIVIQDDSLPAGPPPQIR 23 1 Q7Z422-4;Q7Z422-5;Q7Z422;Q7Z422-2;Q7Z422-3 Q7Z422-4 SZRD1 SUZ domain-containing protein 1 1 S(1)PPKVPIVIQDDSLPAGPPPQIR;S(1)PPKVPIVIQDDSLPAGPPPQIR;S(1)PPKVPIVIQDDSLPAGPPPQIR 167.72 3.646e-10 48308600.0 30005.9 43554.3 39173.5 42751.2 47756.2 46611.0 43334.6 44118.1 39335.6 36936.0 True False 29578.01036359185 43453.452694318235 35952.806044082914 45895.265861822496 44947.27420830164 44617.55618554794 45578.25355017372 46167.987987042456 34905.21050576872 43320.33838587363 0.6827742225863354 1.0030727901351761 0.8299290214179583 1.0594392281291258 1.0375559352269175 1.0299447753182216 1.05212136489304 1.0657347035427918 0.8057464878240886 1.0 15.402756891787359 -4.232159491378346 1.2954561753500273 1.001910110473968 7.253685119762289e-33 0.4843839774190376 0.09121677591310141 4.229670343720675 2.3139195694623145 0.025965296767509485 7.965113830483446 5.8592294920710924e-05 4.232159491378346 -1.001910110473968 S(ph)PPLGLISRPR ddPTM_PC-9_AZD4547_30min_R2 2 SPPLGLISRPR 11 1 Q16584;Q16584-2;E9PID4 Q16584 MAP3K11 Mitogen-activated protein kinase kinase kinase 11 1 S(0.987)PPLGLIS(0.013)RPR;S(1)PPLGLISRPR 95.273 0.0029664 8419000.0 31625.0 32855.0 33051.0 33514.0 37420.0 34431.0 32521.0 32795.0 35241.0 33854.0 True False 41681.092159135886 43474.7362354573 32612.722144860247 25787.865086138423 32224.87891621707 32278.024127045017 35415.30599847508 27727.286304129062 37103.767314072575 32668.781764355623 1.2758691909538373 1.3307731077652818 0.9982840003064779 0.7893733311560195 0.9864120170950822 0.9880388059729562 1.0840718289996398 0.8487395246057768 1.1357560738477213 1.0 14.995625036489729 -5.28573497349611 6.64884448093723 0.9702891130041161 1.3041010666564516 0.6476821540131068 0.09561014356067964 0.0918735796965256 16.895412133903054 0.02447545998771788 0.05402070085753784 5.179227958873194e-06 5.28573497349611 0.3338119536523355 S(ph)PPLGLISRPR ddPTM_PC-9_Lapatinib_30min_R1 2 SPPLGLISRPR 11 1 Q16584;Q16584-2;E9PID4 Q16584 MAP3K11 Mitogen-activated protein kinase kinase kinase 11 1 S(1)PPLGLISRPR;S(1)PPLGLISRPR 75.102 0.018394 3113500.0 15650.599999999999 16894.8 14091.9 11498.2 13900.5 16531.2 14340.2 14325.7 19610.0 15839.2 True False 15427.419574031466 16855.68112861342 12933.318378307074 12343.815984870771 13082.899919434498 15824.199112109374 15082.665388862515 14991.324320539048 17401.31529754534 18576.98461559264 0.8304587581497173 0.9073421482227834 0.6962011675162535 0.664468224542209 0.7042531492680105 0.8518174202947497 0.8119006233230576 0.8069837291007951 0.9367136625036284 1.0 14.181228724479015 -8.326256899153408 1.0997390692306015 1.0038560352658197 0.7709671708885947 0.5256088175235061 0.07154854556588577 0.4263540520060194 1.0786844208658097 0.07543552995104129 0.024904505027408836 4.717838833662214e-09 8.326256899153408 -0.232888864377225 S(ph)PPLIGSESAYESFLSADDK ddPTM_PC-9_AZD4547_30min_R2 4 SPPLIGSESAYESFLSADDK 20 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.982)PPLIGS(0.018)ES(0.001)AYESFLSADDK;S(0.999)PPLIGS(0.001)ESAYESFLSADDK;S(0.995)PPLIGS(0.005)ESAYESFLSADDK;S(1)PPLIGSESAYESFLSADDK 193.38 1.429e-15 15655000.0 105641.0 132932.0 116555.0 73228.0 76959.0 135300.0 130397.0 137184.0 137808.0 91278.0 True False 139232.64053069663 175899.6693730575 115009.40454431587 56346.415961322 66274.57125903666 126839.66961137312 142002.08038753876 115985.36497471061 145092.24953939216 88082.38500286089 1.5807092476682416 1.9969903104615563 1.305702661668169 0.6397012973648691 0.7524157214508223 1.4400117527159761 1.6121507198394616 1.3167827480028322 1.6472334341841404 1.0 16.426565912770712 S(ph)PPLIGSESAYESFLSADDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPPLIGSESAYESFLSADDK 20 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.978)PPLIGS(0.018)ES(0.004)AY(0.001)ESFLSADDK;S(0.998)PPLIGS(0.002)ESAYESFLSADDK;S(0.999)PPLIGS(0.001)ESAYESFLSADDK;S(0.972)PPLIGS(0.028)ESAYESFLSADDK 144.25 1.6584000000000002e-05 18407100.0 89904.0 167699.0 113893.0 97286.0 101245.0 62240.0 102235.0 53484.9 60077.9 67763.8 True False 105122.97151505985 184347.04843591948 116608.64106160786 91835.38082546763 81406.76904331359 58976.024832742005 92550.56068269727 52080.97804693587 60956.4256312797 80048.84052205454 1.3132354051536455 2.3029321503430067 1.4567186770117002 1.1472418616752573 1.0169637500356412 0.7367505194093762 1.1561761554459784 0.6506150208707502 0.761490425516974 1.0 16.288592885536495 -5.772613397469487 2.003593446673117 0.8791489355129326 1.8206919470712268 0.6493396219797771 0.26884210421518157 0.18076495378503007 1.4812587385177016 0.0786638689201218 0.15348309287680725 1.6880550384065925e-06 5.772613397469487 0.9415430115582942 S(ph)PPLIGSESAYESFLSADDK ddPTM_PC-9_Lapatinib_30min_R1 5 SPPLIGSESAYESFLSADDK 20 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.994)PPLIGS(0.006)ESAYESFLSADDK;S(0.978)PPLIGS(0.02)ES(0.001)AYESFLSADDK;S(0.929)PPLIGS(0.061)ES(0.011)AYESFLSADDK;S(0.978)PPLIGS(0.022)ESAYESFLSADDK;S(0.999)PPLIGS(0.001)ESAYESFLSADDK 132.86 1.0663e-05 13697600.0 53434.1 120571.8 87619.4 89911.7 112197.8 108440.9 116544.4 128123.3 94487.0 100103.3 True False 52672.11993538615 120292.62340500955 80415.67115266474 96524.1063546385 105598.54599336197 103803.1354950845 122578.4987758711 134076.37625510257 83844.87906777996 117406.02202573691 0.4486321828009789 1.0245864848281792 0.6849365114766992 0.8221393135479812 0.8994304054541037 0.8841380851173845 1.044056315518469 1.1419889196630078 0.7141446207026764 1.0 16.84114688393972 -3.93168401396879 0.45554072343542734 0.9728356392647634 6.010441939638353e-14 0.35614376344689025 0.15731839347886903 12.631647473744199 1.126523295396754 0.10182607828282457 7.785412135784251 0.00011703506105423523 3.93168401396879 -0.9728356392647033 S(ph)PPLIGSESAYESFLSADDKASGR ddPTM_PC-9_AZD4547_30min_R2 3 SPPLIGSESAYESFLSADDKASGR 24 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.998)PPLIGS(0.001)ES(0.001)AYESFLSADDKASGR;S(1)PPLIGSESAYESFLSADDKASGR;S(0.999)PPLIGS(0.001)ESAYESFLSADDKASGR 133.98 4.2782e-07 67863000.0 41783.3 33419.5 50228.0 57852.0 55487.5 52961.0 38758.5 52363.9 41293.0 45102.7 True False 55069.5202533699 44221.699821058115 49561.94390160782 44515.11520449009 47784.01840896832 49649.34029776744 42207.931414836465 44272.26245771562 43475.66367866973 43523.66820119344 1.2652775496496378 1.016037977696134 1.1387354501578708 1.022779490890188 1.0978858258931874 1.1407434701564523 0.9697696255684419 1.017199705067636 0.9988970478705562 1.0 15.409512532476258 S(ph)PPLIGSESAYESFLSADDKASGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPPLIGSESAYESFLSADDKASGR 24 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.998)PPLIGS(0.001)ES(0.001)AY(0.001)ESFLSADDKASGR;S(1)PPLIGSESAYESFLSADDKASGR;S(0.984)PPLIGS(0.006)ES(0.002)AY(0.007)ESFLSADDKASGR 96.831 2.5148e-06 54297100.0 29318.6 18709.5 27740.6 35713.0 39373.2 43508.0 40120.0 36610.0 38732.9 33410.0 True False 34281.65991125463 20566.855513222104 28402.04111081134 33712.1163931082 31658.304102881128 41226.36388854338 36319.543156353655 35649.02629150136 39299.295387052334 39466.96852658554 0.8686164960493987 0.5211156640867404 0.7196408077726898 0.8541856051193598 0.8021468403775583 1.044578933412955 0.9202516563157941 0.9032623386690479 0.9957515576748628 1.0 15.268358089061131 -6.147276701655562 1.3579757877096967 0.9597701344695282 0.6832663522966557 0.5685615258118043 0.09642595095644504 0.29878995371899764 1.1130115668276972 0.03509976253186449 0.05503842625349315 7.12398995366536e-07 6.147276701655562 -0.2765037821728725 S(ph)PPLIGSESAYESFLSADDKASGR ddPTM_PC-9_Lapatinib_30min_R1 3 SPPLIGSESAYESFLSADDKASGR 24 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.978)PPLIGS(0.011)ES(0.005)AY(0.006)ESFLSADDKASGR;S(0.998)PPLIGS(0.001)ESAYESFLSADDKASGR;S(0.983)PPLIGS(0.017)ESAYESFLSADDKASGR 101.0 1.5191e-06 67631600.0 90679.2 48548.6 54661.1 43675.1 41817.0 41614.8 31420.2 29766.8 44848.7 32179.699999999997 True False 89386.09797947115 48436.188699517115 50167.0753559478 46887.11254986256 39357.40627538518 39835.03201283687 33046.98421578068 31149.874197045974 39797.367128252 37741.91826824504 2.3683506848849816 1.2833525936669181 1.3292137140299234 1.2423086769628247 1.0428035479187439 1.055458594598063 0.8756042546884919 0.8253389235717405 1.0544606356623998 1.0 15.203880130674168 -1.5946426947666472 0.7453815406379638 0.9809935377779516 199.99999999999687 0.9041837906398431 0.12920452862380485 93.77579403453294 0.4655277071497723 0.05014586253158507 31241.861010551147 0.025430640893068582 1.5946426947666472 199.01900646221893 up S(ph)PPLPAVIR ddPTM_PC-9_AZD4547_30min_R2 4 SPPLPAVIR 9 0 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 S(1)PPLPAVIR;S(1)PPLPAVIR;S(1)PPLPAVIR;S(1)PPLPAVIR 106.18 0.0025867 555623000.0 21057.2 21214.6 27716.600000000002 31614.4 20358.8 19137.800000000003 28751.399999999998 34284.700000000004 22916.800000000003 20391.8 True False 27752.951583031012 28071.80457588592 27349.05977429527 24326.188517611008 17532.332038468212 17941.110340639603 31310.21890115793 28986.78739902953 24128.135262425534 19677.889288780847 1.4103622180075015 1.4265658355894288 1.389837058890664 1.236219401411123 0.8909660879362756 0.9117395711169363 1.5911370595528829 1.4730638522067536 1.2261546402835974 1.0 14.26428786059668 -3.63643035693947 0.02129371858915788 1.6331731053120334e-07 2.7439513189247173 0.11012594998071978 0.22099895762252242 6076.831156865237 14.930714727861446 776.3650419091081 1183.3502554708953 0.00023097748225722942 3.63643035693947 2.743951155607407 S(ph)PPLPAVIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SPPLPAVIR 9 0 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 S(1)PPLPAVIR;S(1)PPLPAVIR;S(1)PPLPAVIR;S(1)PPLPAVIR;S(1)PPLPAVIR 104.05 0.0027291 435184100.0 21273.7 23423.899999999998 27874.5 29705.3 37110.0 23054.2 34467.1 27235.6 24224.0 19180.199999999997 True False 24874.917235272398 25749.269988837896 28539.133794629946 28041.00834688201 29838.561896363994 21845.1971674004 31202.126767805512 26520.694358503544 24578.23017269445 22657.418429620346 1.097870761955523 1.1364608933194054 1.259593359379388 1.2376082665368278 1.3169444696027524 0.9641520826945529 1.377126298158247 1.1705082130554065 1.0847762841579074 1.0 14.467695870409766 -8.420888600555541 2.708785964168089 1.004117356169 1.1995556641685554 0.25284643035664656 0.1099001124951233 0.3442965357788552 5.064504561193785 0.1021201302489221 0.027750079845751112 3.794122942885181e-09 8.420888600555541 0.19543830799955542 S(ph)PPLPAVIR ddPTM_PC-9_Lapatinib_30min_R1 6 SPPLPAVIR 9 0 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 S(1)PPLPAVIR;S(1)PPLPAVIR;S(1)PPLPAVIR;S(1)PPLPAVIR;S(1)PPLPAVIR;S(1)PPLPAVIR 120.27 0.0016870000000000001 528242000.0 22299.8 18474.8 20595.199999999997 19672.2 19176.199999999997 22772.46 17216.8 22513.989999999998 25954.6 17426.8 True False 21981.80076271752 18432.022735688315 18901.94215577104 21118.95921253544 18048.293617859756 21798.534970997036 18108.20166155061 23560.072166761347 23031.319633945433 20438.99916024862 1.0754832264717475 0.901806521502108 0.9247978341587798 1.0332677763209297 0.8830321620131725 1.0665167506534543 0.8859632274347793 1.1527018511054512 1.1268320651795203 1.0 14.31903693287501 -7.76971266305146 24.999176844133785 1.1048252320806626 0.966231672162669 0.3559687609499297 0.07712601500170292 178.61363887561262 539702.8657766682 0.03839305635892878 0.01893387451254867 1.6993676124223753e-08 7.76971266305146 -0.1385935599179936 S(ph)PPLQLSEAELLNQLQR ddPTM_PC-9_AZD4547_30min_R2 2 SPPLQLSEAELLNQLQR 17 0 O15015-1;O15015 O15015-1 ZNF646 Zinc finger protein 646 1 S(1)PPLQLSEAELLNQLQR;S(1)PPLQLSEAELLNQLQR 106.31 0.00066466 6450700.0 3912.4700000000003 1826.1200000000001 2380.08 4974.8 4789.8 2266.29 4720.9 2402.12 4048.59 5802.9 True False 5156.554075568515 2416.377578277075 2348.518584083354 3827.9367198938207 4124.818947966237 2124.57852803813 5141.050954404883 2030.9275492262375 4262.5902020397 5599.742237265292 0.920855613898183 0.4315158583901435 0.4193976230645724 0.683591593630789 0.7366087175435144 0.37940648658779985 0.9180870719712955 0.3626823277169393 0.7612118596589889 1.0 12.451144704407715 -8.530404630772583 23.218928022222848 1.0000000173207875 0.6015292858271531 0.2729293590373829 0.1989024199048492 442.13028254482134 1364067.4982392266 0.18001747843353952 0.04648031302393125 2.948460875031695e-09 8.530404630772583 -0.3984707314936343 S(ph)PPLQLSEAELLNQLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPPLQLSEAELLNQLQR 17 0 O15015-1;O15015 O15015-1 ZNF646 Zinc finger protein 646 1 S(1)PPLQLSEAELLNQLQR;S(1)PPLQLSEAELLNQLQR 170.09 1.4775e-05 7382700.0 0.0 990.44 1235.0 1737.8 2116.7200000000003 780.76 1893.33 833.14 722.7 0.0 True False 0.0 1088.7643376100748 1264.4470837635815 1640.4367000236168 1701.9639110016608 739.8155711505725 1713.9800758778415 811.2709577847983 733.2681202859259 0.0 0.0 S(ph)PPLQLSEAELLNQLQR ddPTM_PC-9_Lapatinib_30min_R1 1 SPPLQLSEAELLNQLQR 17 0 O15015-1;O15015 O15015-1 ZNF646 Zinc finger protein 646 1 S(1)PPLQLSEAELLNQLQR 71.268 0.013599000000000002 2504000.0 0.0 0.0 731.04 0.0 0.0 0.0 1104.7 0.0 0.0 0.0 True False 0.0 0.0 670.9367130960054 0.0 0.0 0.0 1161.8959606613876 0.0 0.0 0.0 0.0 S(ph)PPLSPVGTTPVK ddPTM_PC-9_AZD4547_30min_R2 2 SPPLSPVGTTPVK 13 0 C9J4K0;Q9BVC5-2;Q9BVC5 C9J4K0 C2orf49 Ashwin 1 S(1)PPLSPVGTTPVK;S(1)PPLSPVGTTPVK 121.56 0.00019536 8659900.0 34363.0 40954.0 35433.0 37472.0 42320.0 47168.0 40421.0 53243.0 39870.0 36627.0 True False 45289.719205197965 54191.57960088019 34963.1352684891 28833.409336628865 36444.59849637378 44218.57750354213 44018.39069414724 45015.51775242393 41977.4468037818 35344.69987839113 1.281372295167994 1.533230718815965 0.9892044744695849 0.8157774556251612 1.0311191952900156 1.251066713133311 1.2454028707443907 1.273614372375681 1.1876588837424467 1.0 15.10920627117689 -1.5228787454467294 0.013138746543230535 3.059211470784193e-08 2.5326118526356023 0.056461073571288045 0.1876398301509469 35299.91266285775 35.95747513223148 2850.23681496429 4202.0074541194745 0.029999999988506058 1.5228787454467294 2.5326118220434877 S(ph)PPLSPVGTTPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPPLSPVGTTPVK 13 0 C9J4K0;Q9BVC5-2;Q9BVC5 C9J4K0 C2orf49 Ashwin 1 S(1)PPLSPVGTTPVK;S(0.999)PPLS(0.001)PVGTTPVK 108.32 0.00090997 10600000.0 24682.0 44038.0 35412.0 30422.0 30947.0 23582.0 24541.0 15610.7 20667.6 16629.6 True False 28860.17510827892 48409.80160299712 36256.356380757854 28717.55396945473 24883.157504898303 22345.318406261606 22216.298818546224 15200.935665903857 20969.82455074223 19644.414840158828 1.4691287749269288 2.4643035690751947 1.8456317826601505 1.46186863814074 1.2666784787109047 1.1374896421236917 1.1309218930324016 0.7738044522878216 1.0674700530083432 1.0 14.26183157357286 -6.09001025374781 1.2985127003015529 1.0049101586466933 2.0130607690778963 0.7129948377560503 0.24823820140946773 0.22399803568373838 0.766588375301854 0.09108772974095149 0.15394472786415267 8.128113253590512e-07 6.09001025374781 1.008150610431203 S(ph)PPLSPVGTTPVK ddPTM_PC-9_Lapatinib_30min_R1 1 SPPLSPVGTTPVK 13 0 C9J4K0;Q9BVC5-2;Q9BVC5 C9J4K0 C2orf49 Ashwin 1 S(1)PPLSPVGTTPVK 99.161 0.0025765999999999996 4755100.0 12562.0 16001.0 12373.0 13052.0 13725.0 10762.0 12146.0 12096.0 9063.5 10799.0 True False 12382.863576411337 15963.9506675985 11355.7397011612 14011.887620195634 12917.722484388221 10301.734347447313 12774.860449165573 12658.024318619002 8042.673187113827 12665.592761236989 0.9776773823258439 1.2604187556429356 0.896581779884429 1.1062954481750729 1.0199066658706155 0.8133637755175377 1.0086271278406327 0.999402440709988 0.6350017199138446 1.0 13.628626977617255 -6.477450671237087 0.8112092290718347 0.8820318214306033 1.0913370344975475 0.22928177897095625 0.1390434024407725 0.9480974106171006 1.379951868369293 0.0802546941700793 0.10514682343225962 3.3308059267775e-07 6.477450671237087 0.20930521306694416 S(ph)PPPESMDTPTSTR ddPTM_PC-9_AZD4547_30min_R2 2 SPPPESMDTPTSTR 14 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(1)PPPESMDTPTSTR;S(0.999)PPPESMDTPTSTR 73.219 0.01848 6428500.0 5749.299999999999 6581.5 7032.2 8516.8 5116.2 6527.0 3579.0 6789.799999999999 4171.5 6270.7 True False 7577.457807131062 8708.84116675277 6938.948433242143 6553.383343248309 4405.903942040346 6118.865658192406 3897.524066558296 5740.592424082189 4391.996973713962 6051.164701652534 1.252231294425304 1.4392008144108923 1.1467128685734105 1.0829953680584206 0.7281084153662388 1.011188086901912 0.6440948575559193 0.948675619838024 0.7258101853539924 1.0 12.562997137392884 -5.820907012243445 1.706137572418856 0.8376213796592465 1.3412125656501608 0.6986144796849567 0.13030984696992876 0.1802119270932408 1.0698049209336467 0.03840122825134206 0.07643555911333472 1.5104035153980264e-06 5.820907012243445 0.5035911859909142 S(ph)PPPESVDTPTSTK ddPTM_PC-9_AZD4547_30min_R2 2 SPPPESVDTPTSTK 14 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(1)PPPESVDTPTSTK;S(1)PPPESVDTPTSTK 128.96 2.4054e-05 21382600.0 20492.0 36650.0 23375.8 21355.0 14976.2 24569.0 16892.8 23943.4 14538.9 25738.0 True False 27008.029739921356 48496.395770187475 23065.821618523605 16431.934681461065 12897.013138029142 23032.696546059327 18396.226474310144 20243.497694596248 15307.39657224737 24836.9204540375 1.0874145927189987 1.952592949674801 0.9286908842506687 0.6615930792172701 0.519267803828417 0.9273571813656601 0.7406806535598356 0.8150566706552164 0.6163162055688346 1.0 14.600198683497837 -5.440958369299458 6.221560016110003 0.7467884437995107 1.5144156113809284 0.6220562919251784 0.2351705811090572 0.12925166618623984 7.910866094853881 0.05735256731353397 0.12035702270220308 3.622777240538728e-06 5.440958369299458 0.7676271675814177 S(ph)PPPESVDTPTSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPPPESVDTPTSTK 14 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(1)PPPESVDTPTSTK;S(1)PPPESVDTPTSTK 128.95 2.409e-05 10661900.0 12515.699999999999 28674.0 14805.9 17726.0 20816.5 15503.6 24432.2 13511.9 13985.6 15192.4 True False 14634.360813657184 31520.565220135788 15158.928807688428 16732.869688467385 16737.65625749559 14690.56392347202 22117.80514219003 13157.226942041445 14190.11294184426 17946.661857027775 0.8154363708550334 1.756346972559277 0.8446656502725775 0.9323666886783695 0.9326333995055048 0.8185680457181683 1.2324188931842424 0.7331294837367862 0.7906825823593217 1.0 14.131427902139649 S(ph)PPPESVDTPTSTK ddPTM_PC-9_Lapatinib_30min_R1 2 SPPPESVDTPTSTK 14 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(1)PPPESVDTPTSTK;S(1)PPPESVDTPTSTK 135.14 3.4968e-05 13852600.0 22851.3 44026.0 25992.3 12019.4 17921.7 21818.0 45587.0 46489.0 21918.5 14907.3 True False 22525.43627158482 43924.06050194937 23855.3134271795 12903.346771543 16867.580841417872 20884.895000242104 47947.271801095885 48649.04865643842 19449.80771796265 17484.006942271353 1.288345191463218 2.512242224964661 1.3644076844595696 0.7380085591447793 0.9647434307885604 1.1945142248684637 2.7423503067350667 2.7824885232011014 1.1124342252998396 1.0 14.09374823562818 -7.2277757142803845 24.88389560631633 2.057859337069314 1.3530083785948832 0.12151805010145345 0.7006240157569301 1058.6668180151821 782558.4564038567 0.27769086309565344 0.2150858275967106 5.9186721736469505e-08 7.2277757142803845 -0.7048509584744307 S(ph)PPPETIK ddPTM_PC-9_AZD4547_30min_R2 1 SPPPETIK 8 0 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 S(1)PPPETIK 86.794 0.012209000000000001 47643000.0 179920.0 156210.0 202240.0 293450.0 283590.0 265090.0 209460.0 265430.0 225340.0 246160.0 True False 237130.81743151718 206701.82764695745 199558.16545873153 225799.63625730525 244218.4236197226 248513.88039378397 228101.534222213 224413.8924746145 237251.01235927216 237542.0133252726 0.9982689550871476 0.8701695533914463 0.8400962956623224 0.9505671569269383 1.0281062292980898 1.0461891642447574 0.9602576446544953 0.9447334782303061 0.9987749494839805 1.0 17.85782317548267 -5.996823248657881 24.375768707683267 0.9938199167191661 0.8988697606673649 0.44798892660742373 0.04655637613062651 66.52570558336488 510444.9775170304 0.013761926120628584 0.02028516357107757 1.0073415583464016e-06 5.996823248657881 -0.09495015605180124 S(ph)PPPETIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPPPETIK 8 0 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 S(1)PPPETIK;S(1)PPPETIK;S(1)PPPETIK;S(1)PPPETIK 81.191 0.018233000000000003 99614000.0 669220.0 705860.0 711340.0 742030.0 773930.0 714090.0 765950.0 678140.0 676670.0 592840.0 True False 782505.7283025048 775933.1159337754 728301.0433719743 700456.4647937175 622283.97220299 676641.8633163997 693393.6710022201 660339.5435487229 686565.0186161301 700317.1990811422 1.1173590043614505 1.1079738109414503 1.0399588134170465 1.0001988609058268 0.8885744531470361 0.9661934109346366 0.9901137254832436 0.9429149311413851 0.9803629262810398 1.0 19.41764899347868 -5.568721695057669 1.90748807501572 0.9599871642372759 1.1161680016689022 0.7934090387313346 0.030223403579926988 0.14809994902796397 1.0637933138068079 0.00914342210896323 0.02308667163086544 2.6994687540507403e-06 5.568721695057669 0.15618083743162625 S(ph)PPPFFYR ddPTM_PC-9_AZD4547_30min_R2 2 SPPPFFYR 8 0 Q8WYL5-4;Q8WYL5 Q8WYL5-4 SSH1 Protein phosphatase Slingshot homolog 1 1 S(0.997)PPPFFY(0.003)R;S(0.999)PPPFFY(0.001)R 78.264 0.022374 8186900.0 3749.2 3221.3 9349.400000000001 5990.9 3194.3 5553.5 3563.7 3058.6 2845.2 4233.8 True False 4941.367611795483 4262.522229045157 9225.420847210567 4609.79056348233 2750.826582631539 5206.238767086186 3880.8623961983235 2585.9636496358935 2995.5914634090764 4085.5759506684244 1.209466589646203 1.0433099960723489 2.258046590885487 1.1283086201660604 0.6733020303248769 1.2742973891439748 0.9498935873566103 0.6329495965465566 0.7332115470571486 1.0 11.996323756570913 -5.9928515065010055 24.99483072907977 0.8840778378062097 1.4968445843658178 0.40218284994659814 0.3417603927381768 182.31058058118538 637443.7396751626 0.0980125004188034 0.1450303977357179 1.0165962269342085e-06 5.9928515065010055 0.612766746559608 S(ph)PPPFFYR ddPTM_PC-9_Lapatinib_30min_R1 2 SPPPFFYR 8 0 Q8WYL5-4;Q8WYL5 Q8WYL5-4 SSH1 Protein phosphatase Slingshot homolog 1 1 S(1)PPPFFYR;S(1)PPPFFYR 96.948 0.0059635 6142800.0 3103.7 919.11 0.0 1438.2 2568.2 1218.7 1678.08 1756.0900000000001 2331.0 1465.4 True False 3059.440668851127 916.9818572649498 0.0 1543.970025694557 2417.1435252754686 1166.5790419284558 1764.9627714915 1837.684352321731 2068.458233481805 1718.692437477237 1.780097824449552 0.5335345855195192 0.0 0.8983399193638484 1.4063851522052688 0.6787596294080431 1.02692182324499 1.0692339782556761 1.2035069151278561 1.0 10.747095680190068 -5.995824744631346 24.99556617640663 1.056093814315495 0.6977310573740569 0.0745509815197053 0.44455515338746104 278.13944632042427 1665075.1314891318 0.12742217858922034 0.18813179667814559 1.0096602425762315e-06 5.995824744631346 -0.35836275694143804 S(ph)PPPGMGLNQNR ddPTM_PC-9_Lapatinib_30min_R1 2 SPPPGMGLNQNR 12 0 P23246;P23246-2 P23246 SFPQ Splicing factor, proline- and glutamine-rich 1 S(1)PPPGMGLNQNR;S(1)PPPGMGLNQNR 83.137 0.011351 17507600.0 1760.7 4594.4 4795.7 0.0 3470.9 0.0 3693.2 2025.8 4548.3 3485.3 True False 1735.5920951271637 4583.761949079093 4401.416057937343 0.0 3266.7484860519544 0.0 3884.4158250336127 2119.9260635464943 4036.022558277688 4087.7294611296707 0.4245858517866595 1.1213467017977117 1.0767385904058786 0.0 0.799159659932379 0.0 0.9502624530245035 0.5186072326226401 0.9873507032831637 1.0 11.997084001974285 -8.273087644100862 22.298953322590364 0.9936758928517387 0.6206536394228135 0.14118027609689565 0.3766392667968287 406.2221271943706 777619.8231280632 0.3461501941276695 0.09330174878863765 5.332272750986543e-09 8.273087644100862 -0.37302225342892525 S(ph)PPPGPDGHAK ddPTM_PC-9_AZD4547_30min_R2 2 SPPPGPDGHAK 11 0 P57081-3;P57081-2;P57081 P57081-3 WDR4 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 1 S(1)PPPGPDGHAK;S(1)PPPGPDGHAK 119.88 0.00052217 28488000.0 80698.0 86973.0 105939.0 132544.0 114373.0 110716.0 112224.0 117983.0 103906.0 116419.0 True False 106358.28537732639 115085.32140028695 104534.17964068716 101988.0285843865 98494.28317168598 103792.9110176853 122211.71859330487 99751.43832962544 109398.25903169674 112343.20624518581 0.9467264548708224 1.0244083754305227 0.9304895519230982 0.9078255107104614 0.8767266527601594 0.9238913013677059 1.087842537861892 0.8879169614575607 0.9737861566184803 1.0 16.777553357185766 S(ph)PPPGPDGHAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPPPGPDGHAK 11 0 P57081-3;P57081-2;P57081 P57081-3 WDR4 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 1 S(1)PPPGPDGHAK 74.133 0.013134 13283000.0 25688.0 32689.0 29518.0 32438.0 35307.0 27893.0 31311.0 27411.0 22830.0 26620.0 True False 30036.471038873246 35934.14788592516 30221.821067638386 30620.60402541495 28388.84680342021 26430.241977179827 28344.995407990755 26691.490294355197 23163.845559883328 31445.995276195954 0.955176351553112 1.1427257293117592 0.961070584734068 0.9737521028184529 0.9027809917948455 0.8404962776670973 0.901386493225336 0.8488041182961116 0.7366230693743676 1.0 14.940588677638052 -6.066570623384137 1.2489593217688715 0.856077406734461 1.0448058170835537 0.44476667859840535 0.07710860498985164 0.38275276276778714 1.2149824763739419 0.0281233950538292 0.049569697591265255 8.578855971531522e-07 6.066570623384137 0.1887284103490927 S(ph)PPPGPDGHAK ddPTM_PC-9_Lapatinib_30min_R1 3 SPPPGPDGHAK 11 0 P57081-3;P57081-2;P57081 P57081-3 WDR4 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 1 S(1)PPPGPDGHAK;S(1)PPPGPDGHAK;S(1)PPPGPDGHAK 136.24 4.507899999999999e-05 33858000.0 93943.0 163927.0 173044.0 166418.0 199370.0 169809.0 161660.0 182477.0 181493.0 183893.0 True False 92603.3555929637 163547.43710314474 158816.990289157 178656.9348741738 187643.44857650134 162546.6649141127 170029.96379154496 190955.54758503995 161051.34713398237 215678.66002797947 0.42935798831905986 0.7582921605778158 0.7363593146793199 0.8283477598154453 0.8700139761261444 0.7536520529802343 0.7883485726844157 0.8853706136725245 0.7467189712375326 1.0 17.718523912896956 -4.482585860751849 1.495948760470129 0.8238304098725818 5.6242847592715e-19 0.7138672879971741 0.07510517268810266 1.288500845140406 1.5162043653504071 0.019759433618288434 1.952365482109368 3.2916537035099816e-05 4.482585860751849 -0.8238304098725818 down S(ph)PPPGPDGHAKK ddPTM_PC-9_AZD4547_30min_R2 1 SPPPGPDGHAKK 12 1 P57081-3;P57081-2;P57081 P57081-3 WDR4 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 1 S(1)PPPGPDGHAKK 75.911 0.0070524 1845300.0 20469.0 16121.0 28682.0 52813.0 38863.0 33646.0 24853.0 32070.0 24432.0 32066.0 True False 26977.716218351063 21331.797986662834 28301.657939514113 40637.778802716166 33467.54327421019 31542.110301140143 27064.868853359403 27114.318395286442 25723.42564108343 30943.379100130784 0.8718413115469035 0.6893816579512699 0.9146272567043104 1.3132947979344767 1.081573643457341 1.0193492507418762 0.874657831188353 0.8762558965375518 0.8313062887490109 1.0 14.917343131113693 -7.270537747032783 23.22349533532135 0.8852429810882194 0.9849582311714311 0.06735593740677293 0.15482271637231368 796.6891967681618 2033524.080556397 0.07304533643217645 0.05014623178576154 5.363672506497424e-08 7.270537747032783 0.09971525008321169 S(ph)PPPGRDESYPR ddPTM_PC-9_AZD4547_30min_R2 1 SPPPGRDESYPR 12 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 S(0.998)PPPGRDES(0.002)YPR 94.402 0.023746 5315600.0 7974.1 7556.4 14228.0 14206.0 11575.0 14123.0 10858.0 11140.0 11349.0 9600.6 True False 10509.697928416295 9998.858526544198 14039.327423589943 10931.026180512103 9968.011049043633 13239.88657739411 11824.340965266827 9418.568971733419 11948.884970557294 9264.485916195208 1.1344070273823113 1.0792674970842404 1.5153919548895698 1.1798848073592105 1.0759378490304137 1.4291010528980914 1.2763083750385704 1.0166315818202993 1.2897515392267476 1.0 13.177495208380055 -9.533137541971469 0.613747163434685 0.9873661091035565 1.2324367682117912 0.1558874329077179 0.1521187411515393 8.788877659241392 3.7803795155306466 0.44618126005314285 0.06240437075648601 2.9299651721938055e-10 9.533137541971469 0.24507065910823467 S(ph)PPPGRDESYPR ddPTM_PC-9_Lapatinib_30min_R1 1 SPPPGRDESYPR 12 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 S(1)PPPGRDESYPR 118.76 0.0027513999999999998 4665700.0 4222.6 4935.7 5765.8 5241.4 7670.8 5026.3 5117.5 7020.9 6412.6 3646.2 True False 4162.384949669998 4924.271689898504 5291.758180631632 5626.870040797834 7219.618625373049 4811.3368658775735 5382.459109880189 7347.116645055573 5690.345460328367 4276.440811743895 0.9733292550756978 1.1514883302898862 1.2374211204091703 1.3157834490180271 1.6882306907058424 1.1250797281385856 1.258630563785418 1.718044740588724 1.3306264977879805 1.0 12.062194857116847 -5.132103691366713 1.3465574886329066 1.3778703035045394 0.9405806873829129 0.23333280673519485 0.2104365294015139 1.0116057403292127 2.5060815505634153 0.06353464923896608 0.5087672604257483 7.377280704774535e-06 5.132103691366713 -0.43728961612162653 S(ph)PPPTVDESADNAFHLGPLR ddPTM_PC-9_AZD4547_30min_R2 2 SPPPTVDESADNAFHLGPLR 20 0 Q96JK2-2;Q96JK2-3;Q96JK2 Q96JK2-2 DCAF5 DDB1- and CUL4-associated factor 5 1 S(0.969)PPPT(0.031)VDESADNAFHLGPLR;S(0.91)PPPT(0.09)VDESADNAFHLGPLR 124.1 4.8962e-06 6512200.0 6965.8 7903.7 8728.0 10810.7 9035.5 8444.1 5792.5 10619.0 8859.7 7540.6 True False 9180.77950235917 10458.416459722532 8612.261017226105 8318.460138650022 7781.076789082832 7916.08909213153 6308.021278440611 8978.077550344451 9328.005654563967 7276.605889180011 1.2616843130133761 1.4372657553535682 1.183554688599001 1.1431786007565974 1.069327775557138 1.0878820720388886 0.8668906045633663 1.2338276508412325 1.2819171185888047 1.0 12.829049959169167 -5.5079734465162105 2.9185566597317445 1.0959507615665929 1.3491119974228272 0.41920799152562827 0.11637520472755525 0.2540171825797934 4.338953239429555 0.03372145368572313 0.07438630426039908 3.10474941184555e-06 5.5079734465162105 0.2531612358562343 S(ph)PPPTVDESADNAFHLGPLR ddPTM_PC-9_Lapatinib_30min_R1 2 SPPPTVDESADNAFHLGPLR 20 0 Q96JK2-2;Q96JK2-3;Q96JK2 Q96JK2-2 DCAF5 DDB1- and CUL4-associated factor 5 1 S(1)PPPTVDESADNAFHLGPLR;S(1)PPPTVDESADNAFHLGPLR 208.72 1.423e-21 6437600.0 16112.900000000001 16267.9 19801.9 15651.4 19586.9 20767.1 16162.4 17377.9 20956.3 15219.8 True False 15883.127091256025 16230.232677046806 18173.864219544477 16802.45616753983 18434.83705132703 19878.93954347455 16999.209988769446 18185.340675142957 18595.980814377846 17850.522150891273 0.8897850134015819 0.9092301356706495 1.0181138717355145 0.941286536354954 1.0327337707825306 1.113633504691738 0.9523088369670284 1.0187567916177156 1.0417611685072952 1.0 14.123678655119441 -5.068455968347643 0.9672194847714872 1.02362998902956 0.8430452886440801 0.5053313995696229 0.0454924751956723 1.147147251049777 1.1646921484315023 0.016204809522262765 0.19654382478667878 8.541694443868695e-06 5.068455968347643 -0.1805847003854798 S(ph)PPQSPGPGK ddPTM_PC-9_AZD4547_30min_R2 2 SPPQSPGPGK 10 0 Q86VQ6;H0YBI6;H0YBQ0 Q86VQ6 TXNRD3 Thioredoxin reductase 3 1 S(1)PPQSPGPGK;S(1)PPQSPGPGK 102.4 0.0032306999999999995 24259000.0 99983.0 111852.0 125363.0 104754.0 102189.0 112851.0 113704.0 139796.0 117598.0 110512.0 True False 131775.51422440753 148005.97161492537 123700.60470927086 80604.58373316667 88001.82126053749 105794.40913017774 123823.43572616503 118193.7403924998 123813.99019892488 106643.0085172349 1.2356695113595833 1.3878638053520935 1.1599504405324352 0.7558356131723338 0.825200099698193 0.9920426158371177 1.16110223677864 1.1083121344368125 1.1610136653160428 1.0 16.702429860573403 -5.524849510479566 24.99864861955789 1.0004985316642119 1.3023018149792505 0.4880421152098844 0.1286873669922811 54.45013850050658 690682.9022749674 0.03947459480040944 0.06897054967592452 2.9864172778084622e-06 5.524849510479566 0.3018032833150386 S(ph)PPQSPGPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPPQSPGPGK 10 0 Q86VQ6;H0YBI6;H0YBQ0 Q86VQ6 TXNRD3 Thioredoxin reductase 3 1 S(1)PPQSPGPGK;S(1)PPQSPGPGK 94.85 0.006143600000000001 15561900.0 77335.0 120519.0 105340.0 83572.0 99825.0 76604.0 88678.0 52600.0 67374.0 64547.0 True False 90426.28806412574 132483.3298376768 107851.7051041748 78889.73178407976 80265.00784975843 72586.7513863652 80277.77786687753 51219.305734306814 68359.2172909147 76248.8601462291 1.1859362604333672 1.7375122668535892 1.414469736299509 1.0346348998894677 1.0526715769367203 0.9519716261614829 1.0528390550746833 0.6717386415492518 0.8965277272318073 1.0 16.218428150244478 -5.7997191893336835 2.9174372951959855 0.9335237675036943 1.4907413283013728 0.6693549035651754 0.16040367242262948 0.14297571003765622 2.4813500375458615 0.04696198088556259 0.08028614966993092 1.585918300647177e-06 5.7997191893336835 0.5572175607976786 S(ph)PPQSPGPGK ddPTM_PC-9_Lapatinib_30min_R1 4 SPPQSPGPGK 10 0 Q86VQ6;H0YBI6;H0YBQ0 Q86VQ6 TXNRD3 Thioredoxin reductase 3 1 S(1)PPQSPGPGK;S(1)PPQSPGPGK;S(1)PPQSPGPGK;S(0.997)PPQS(0.003)PGPGK 88.056 0.010232 39403600.0 162237.0 190543.0 164899.0 148146.0 187085.0 161299.0 157414.0 159041.0 158015.0 130755.0 True False 159923.4706293777 190101.80939042676 151341.64074854724 159041.15104056857 176081.02812326184 154400.61777633376 165564.12668738264 166430.62546771523 140217.68672828277 153355.82752991447 1.0428261723421113 1.2396125563167426 0.9868659260374417 1.0370727581874584 1.1481860908671009 1.006812849979343 1.0796076637849759 1.0852579138882108 0.9143290410723459 1.0 17.22652346457462 -8.250446710456867 24.59018074884858 0.9571645213323835 1.0792294598739436 0.3148377446823014 0.07145738184690834 588.3715441204172 1316173.9343248797 0.04808616511928202 0.017770819675331766 5.617632045548124e-09 8.250446710456867 0.12206493854156009 S(ph)PPRASYVAPLTAQPATYR ddPTM_PC-9_Lapatinib_30min_R1 1 SPPRASYVAPLTAQPATYR 19 1 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 S(0.907)PPRAS(0.076)Y(0.017)VAPLTAQPATYR 51.938 0.023042 12301000.0 36787.0 4359.3 10294.0 7043.5 1771.1 4549.8 4671.9 3564.6 2790.2 3586.4 True False 36262.41063409041 4349.206308684595 9447.66705598911 7561.502486427211 1666.9273801165737 4355.215660101821 4913.788122217733 3730.2243292120793 2475.9382938914323 4206.304461422385 8.620966686236516 1.0339732533802097 2.246073041701391 1.79765933630735 0.3962926115797364 1.0354019068389264 1.1681960179734845 0.8868174815739998 0.5886255539985757 1.0 12.038337563901319 -4.760871633263338 24.99691252232672 1.1559232212085628 8.62097520493906 0.9506011969335589 0.5123862654293064 2.905383460120564 127808.82726066274 0.138031423942877 0.7954159747861531 1.734316543194505e-05 4.760871633263338 7.465051983730498 S(ph)PPSLHLLEAFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPPSLHLLEAFK 12 0 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 1 S(0.987)PPS(0.013)LHLLEAFK 94.402 0.0027883 1932200.0 2704.8 3483.0 6511.5 6110.5 6735.7 5512.5 5702.0 4503.8 5288.0 4475.5 True False 3162.6692177648847 3828.7692216549094 6666.758855001266 5768.148495508287 5415.887937627029 5223.414795798364 5161.865281094925 4385.580022170554 5365.3269960868665 5286.872721961497 0.5982117187401278 0.7242030256847923 1.261002336467789 1.0910322224228297 1.024402935809218 0.9879970770055556 0.9763551257159465 0.8295225273634823 1.0148394482430934 1.0 12.36819887984978 -5.069993355827698 6.750130307934433 1.0162766144354318 0.627476769709875 0.6748924850703535 0.10203537586956248 0.12913013225368244 10.400361971331419 0.02821091713185922 0.07756375610767696 8.511510596688525e-06 5.069993355827698 -0.38879984472555684 S(ph)PPSLHLLEAFK ddPTM_PC-9_Lapatinib_30min_R1 1 SPPSLHLLEAFK 12 0 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 1 S(0.881)PPS(0.119)LHLLEAFK 109.24 0.00075744 1153000.0 4287.7 4036.3 7214.5 5534.0 6413.1 6620.8 4367.5 6447.4 9984.1 5269.8 True False 4226.55661173212 4026.9541953395355 6621.351658775349 5940.988820882825 6035.894066639712 6337.643817838615 4593.6277796583745 6746.969741390892 8859.585520766062 6180.677908432881 0.6838338244362209 0.6515392413258071 1.0712986110700278 0.9612196119744364 0.9765747634906478 1.0253962286550429 0.743223938815976 1.0916229322005868 1.4334326512433362 1.0 12.593549368988672 -4.121758412488298 0.47519095469547873 1.0771244627317142 1.7633138652649766e-28 0.3988954729250237 0.16955458149291647 9.706947550090444 1.055532318967263 0.11320358026405637 6.676307279255227 7.555123840513722e-05 4.121758412488298 -1.0771244627317142 S(ph)PPSPELQGPPSTEK ddPTM_PC-9_AZD4547_30min_R2 1 SPPSPELQGPPSTEK 15 0 A0A087WSV0;Q9HB09;Q9HB09-3;I6LJZ7 A0A087WSV0 BCL2L12 Bcl-2-like protein 12 1 S(0.917)PPS(0.083)PELQGPPSTEK 122.16 5.4494e-05 5808800.0 16674.0 18841.0 20120.0 20093.0 24359.0 23837.0 24687.0 25506.0 20098.0 20769.0 True False 21975.985159254767 24930.98479416377 19853.195653825547 15460.869283755424 20977.173316946337 22346.468621776057 26884.095174944046 21564.63376957207 21160.33924911979 20041.88363159161 1.0965029816166818 1.2439441946896435 0.9905853171670632 0.77142795397658 1.0466667556077638 1.1149884428303825 1.3413956327222258 1.0759783943451393 1.0558059131610356 1.0 14.290730485799637 -6.762872004657691 4.893840360841238 1.1375020286907396 1.024248239433981 0.08510741443834025 0.13782668239353643 0.4399532311704521 28.148553918747474 0.0523907298256043 0.048982947573285696 1.7263466061827293e-07 6.762872004657691 -0.11325378925675866 S(ph)PPSPVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPPSPVER 8 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 S(0.964)PPS(0.036)PVER 74.92 0.027104000000000003 50468000.0 16580.0 6425.5 17373.0 18605.0 19439.0 16507.0 19693.0 17561.0 16454.0 18015.0 True False 19386.666530073107 7063.381175349877 17787.23820746939 17562.62216822384 15630.067494029094 15641.343861087285 17827.536475026733 17100.042357417526 16694.608622090243 21280.976893338466 0.9109857422072419 0.33191057021263487 0.8358280870572857 0.8252733065896719 0.7344619362338454 0.7349918163758478 0.8377217157078557 0.8035365313878196 0.7844850687900572 1.0 14.37727675815295 -14.522878744608384 0.06529705386058808 1.9137694417278848 0.3988024591142883 0.22516971687677356 0.14716495083135797 485.5815833830741 2.2904155792456073 68.07641778977599 9.673857184664868 3.000000004641689e-15 14.522878744608384 -1.5149669826135965 S(ph)PPSSSEIFTPAHEENVR ddPTM_PC-9_AZD4547_30min_R2 6 SPPSSSEIFTPAHEENVR 18 0 I3L3A7;I3L2L5;I3L317;I3L4Q0;C9JLW8 I3L3A7 FAM195B Protein FAM195B 1 S(0.997)PPS(0.003)SSEIFTPAHEENVR;S(0.993)PPS(0.006)SSEIFTPAHEENVR;S(0.992)PPS(0.007)S(0.001)SEIFTPAHEENVR;S(0.915)PPS(0.06)S(0.019)S(0.006)EIFTPAHEENVR;S(0.29)PPS(0.29)S(0.29)S(0.129)EIFT(0.001)PAHEENVR;S(0.601)PPS(0.234)S(0.074)S(0.09)EIFT(0.002)PAHEENVR 176.67 1.0868e-08 210495600.0 40210.3 40098.950000000004 57879.3 80239.7 82772.9 61971.240000000005 60206.85999999999 72248.48 59803.78 71754.75 True False 52996.338973802434 53060.151409794256 57111.78266433718 61741.67685600706 71281.3115992556 58096.16856620184 65565.15390385754 61084.137520906865 62964.885718963335 69242.63804294594 0.7653714600089736 0.7662930372018045 0.8248065683013852 0.8916713545447734 1.0294424593564044 0.8390230385238819 0.9468898897698332 0.8821751921557498 0.9093368984571473 1.0 16.07937306986601 -5.6592110247033345 2.4620450169734838 0.9265761871390288 0.768149492984161 0.6306318586968016 0.05182019302280211 0.18380081875945575 2.2494509143802777 0.014689252934016628 0.029561078827941314 2.1917397051295224e-06 5.6592110247033345 -0.15842669415486776 S(ph)PPSSSEIFTPAHEENVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SPPSSSEIFTPAHEENVR 18 0 I3L3A7;I3L2L5;I3L317;I3L4Q0;C9JLW8 I3L3A7 FAM195B Protein FAM195B 1 S(0.909)PPS(0.045)S(0.045)S(0.001)EIFTPAHEENVR;S(1)PPSSSEIFTPAHEENVR;S(0.999)PPS(0.001)SSEIFTPAHEENVR;S(0.996)PPS(0.004)SSEIFTPAHEENVR;S(0.747)PPS(0.043)S(0.087)S(0.124)EIFTPAHEENVR 234.62 1.7622999999999998e-43 183635300.0 50428.0 61258.7 65111.5 60284.1 80067.2 61005.0 69156.9 65323.8 56066.3 43827.4 True False 58964.46440159996 67340.05889135563 66664.00509673888 56906.57732068921 64378.60692720446 57805.79040683521 62605.85777940265 63609.11946628731 56886.16357048125 51772.96068249248 1.1389046255865247 1.3006800848097395 1.2876220370236997 1.0991563273670906 1.2434793389935435 1.116524719560471 1.2092385089457212 1.228616610442318 1.0987620337060973 1.0 15.659911201897728 -14.522878656903453 0.15863412547989378 0.24867176437475677 1.25112484958469 0.4532950022010038 0.06778860614347602 120.24701686066415 1.0972723515646572 28.19787619284526 0.29077703006009453 3.0000006104859534e-15 14.522878656903453 1.0024530852099334 S(ph)PPSSSEIFTPAHEENVR ddPTM_PC-9_Lapatinib_30min_R1 7 SPPSSSEIFTPAHEENVR 18 0 I3L3A7;I3L2L5;I3L317;I3L4Q0;C9JLW8 I3L3A7 FAM195B Protein FAM195B 1 S(0.755)PPS(0.211)S(0.032)S(0.003)EIFTPAHEENVR;S(0.963)PPS(0.009)S(0.028)SEIFTPAHEENVR;S(1)PPSSSEIFTPAHEENVR;S(0.816)PPS(0.054)S(0.122)S(0.006)EIFT(0.001)PAHEENVR;S(0.398)PPS(0.186)S(0.398)S(0.018)EIFTPAHEENVR;S(0.986)PPS(0.004)S(0.005)S(0.004)EIFTPAHEENVR;S(0.923)PPS(0.05)S(0.016)S(0.011)EIFTPAHEENVR 193.47 1.2201000000000001e-14 184333700.0 48988.69 63800.600000000006 69821.7 51818.9 63628.240000000005 62931.55 55850.8 65949.4 67692.3 63094.89 True False 48290.10229717454 63652.873630597176 64081.229345556225 55629.83476878294 59885.75202113292 60240.11430710818 58742.4811439368 69013.64988412155 60068.08034247973 74000.7576678436 0.6525622685368612 0.8601651609610071 0.8659536924363435 0.7517468269511571 0.8092586334039085 0.8140472639145019 0.7938091851384225 0.9326073415882179 0.8117225044113542 1.0 16.175252421615966 -14.522878743471022 0.1112079468232974 1.614992791822982 0.7083009265602234 0.5011559753639572 0.06378555719416787 144.41674542623485 1.06064980252231 20.03192846064887 0.765815938532633 3.000000012498309e-15 14.522878743471022 -0.9066918652627587 S(ph)PPSTGSTYGSSQK ddPTM_PC-9_AZD4547_30min_R2 4 SPPSTGSTYGSSQK 14 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.949)PPS(0.014)T(0.029)GS(0.007)TYGSSQK;S(0.99)PPS(0.008)T(0.002)GSTYGSSQK;S(0.903)PPS(0.027)T(0.07)GSTYGSSQK;S(0.442)PPS(0.01)T(0.092)GS(0.427)T(0.029)YGSSQK 156.6 1.719e-12 88030000.0 23906.8 40258.9 30834.600000000002 15516.6 18083.68 35515.3 33905.0 41268.899999999994 37834.8 25523.3 True False 31508.6651076689 53271.8021193015 30425.713057030276 11939.487599080257 15573.0731790384 33294.522676635635 36922.47931731183 34891.7397699793 39834.670286724955 24629.737035687896 1.279293606018351 2.1629058419142657 1.235324316006466 0.484759036679126 0.6322874319150623 1.3518017926213615 1.499101645454519 1.4166509256441515 1.6173404624257854 1.0 14.588113604246484 -6.982005883720228 24.968176259592415 1.4190597668486271 1.1625395111979822 0.054619551838890223 0.4451465386387167 812.1327579022915 1126890.7339937699 0.17724426528027823 0.1562856659806915 1.0423033084158187e-07 6.982005883720228 -0.25652025565064496 S(ph)PPSTGSTYGSSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SPPSTGSTYGSSQK 14 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.991)PPS(0.003)T(0.006)GSTYGSSQK;S(0.968)PPS(0.022)T(0.007)GS(0.003)TYGSSQK;S(1)PPSTGSTYGSSQK;S(0.863)PPS(0.067)T(0.067)GS(0.003)TYGSSQK;S(0.713)PPS(0.023)T(0.158)GS(0.073)T(0.033)YGSSQK 126.76 3.0882e-05 74018800.0 26006.999999999996 66044.3 40969.09999999999 23843.1 30218.300000000003 18300.2 28839.4 11601.699999999999 20177.7 18631.399999999998 True False 30409.47143833602 72600.74163242702 41945.95872017698 22507.248407373158 24297.241038881602 17340.505296339084 26107.523252825158 11297.16766801725 20472.76069004196 22009.125333918746 1.381675599414726 3.2986654640264335 1.905843966253995 1.0226325701679178 1.1039621370794137 0.7878779839385643 1.1862135753568672 0.5132947128347229 0.9301941980625164 1.0 14.425814191680706 -5.67481310748504 3.5021484881559752 0.9176393636794438 2.392803048379647 0.6125322708974216 0.4659347624580149 0.13301351050636134 3.187077821412881 0.12242565911033697 0.2225646759287853 2.1143987458103124e-06 5.67481310748504 1.4751636847002034 S(ph)PPSTGSTYGSSQK ddPTM_PC-9_Lapatinib_30min_R1 3 SPPSTGSTYGSSQK 14 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.988)PPS(0.009)T(0.003)GSTYGSSQK;S(0.993)PPS(0.002)T(0.004)GSTYGSSQK;S(0.979)PPS(0.01)T(0.01)GS(0.001)TYGSSQK 132.56 1.286e-05 70798000.0 10463.1 24436.6 17094.8 15061.599999999999 24776.0 23092.1 29370.2 30068.5 21609.0 19555.6 True False 10313.894275302455 24380.01855408024 15689.331531836284 16169.280308024716 23318.724391490145 22104.50471331427 30890.8452465077 31465.592280456007 19175.166867142132 22935.759403800912 0.4496861906213246 1.0629697549949004 0.684055463593512 0.7049812488591568 1.0166972883237417 0.9637572632389539 1.346842051429458 1.3719010444119646 0.8360380194764524 1.0 14.485311055443704 -6.5730031324613005 1.808145506924316 1.1566926771887203 0.7461234419359913 0.4169047388991801 0.2089895801117929 0.33544038996910336 2.2332649429828466 0.0796300630823494 0.08361057745971757 2.6729871289826256e-07 6.5730031324613005 -0.4105692352527289 S(ph)PPSTGSTYGSSQKEESAASGGAAYTK ddPTM_PC-9_AZD4547_30min_R2 2 SPPSTGSTYGSSQKEESAASGGAAYTK 27 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.185)PPS(0.111)T(0.111)GS(0.12)T(0.12)Y(0.111)GS(0.12)S(0.12)QKEES(0.002)AASGGAAYTK;S(0.888)PPS(0.04)T(0.054)GS(0.009)T(0.002)Y(0.002)GS(0.002)S(0.002)QKEESAASGGAAYTK 60.138999999999996 0.00097412 70508000.0 66804.0 72307.0 76008.0 46183.0 61233.0 102037.0 91027.0 103408.0 93460.0 72490.0 True False 88046.28239047948 95678.82370954838 75000.08425725505 35536.22287023726 52731.854908517365 95656.61025968702 99128.22665733495 87428.66967944455 98400.10479762836 69952.14716423895 1.2586644722106635 1.367775366278699 1.0721627183389262 0.5080076067830002 0.7538275384844088 1.3674578141982858 1.4170862607632928 1.249835397820926 1.4066774042917816 1.0 16.09408072079448 -6.783615631329123 24.990022808957697 1.31188086559255 0.9905143247783925 0.25447891017098123 0.2517921920152725 359.835826356945 405489.69922207645 0.09931978423448125 0.087659465182508 1.645827704756484e-07 6.783615631329123 -0.3213665408141575 S(ph)PPSTGSTYGSSQKEESAASGGAAYTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPPSTGSTYGSSQKEESAASGGAAYTK 27 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.686)PPS(0.124)T(0.124)GS(0.024)T(0.024)Y(0.005)GS(0.005)S(0.005)QKEES(0.002)AASGGAAYTK;S(0.573)PPS(0.113)T(0.113)GS(0.113)T(0.022)Y(0.021)GS(0.022)S(0.022)QKEES(0.001)AASGGAAYTK 52.707 0.0046451 90751000.0 40154.0 64381.0 54116.0 41452.0 51627.0 36332.0 53177.0 24597.0 32355.0 39133.0 True False 46951.27912234955 70772.32020079372 55406.33067607288 39129.57882919721 41511.05995752043 34426.68596116939 48139.68959185987 23951.354812675756 32828.130665353725 46227.50312334247 1.0156568265665558 1.5309570151769112 1.1985577185131504 0.8464566802319641 0.8979732227103463 0.7447230249341699 1.0413646928629343 0.51811915406224 0.7101428467326681 1.0 15.496463820235935 -5.730881938565281 3.724297493108685 0.8074774356594553 1.2932673355465887 0.5355685277885054 0.18210865281728156 0.15569716545943427 4.552293594787357 0.050430764668567316 0.08755893712061757 1.8583095613824124e-06 5.730881938565281 0.4857898998871334 S(ph)PPSTGSTYGSSQKEESAASGGAAYTK ddPTM_PC-9_Lapatinib_30min_R1 3 SPPSTGSTYGSSQKEESAASGGAAYTK 27 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.726)PPS(0.162)T(0.036)GS(0.036)T(0.01)Y(0.009)GS(0.01)S(0.01)QKEES(0.001)AASGGAAYTK;S(0.956)PPS(0.035)T(0.007)GSTYGSSQKEESAASGGAAYTK;S(0.494)PPS(0.226)T(0.226)GS(0.015)T(0.014)Y(0.012)GS(0.006)S(0.006)QKEES(0.001)AASGGAAYTK 85.376 4.0877e-07 138791000.0 34729.5 76187.0 62656.0 59963.0 78109.0 70914.0 75396.0 81710.0 66098.0 63482.0 True False 34234.2509613897 76010.59368241548 57504.665539154266 64372.87905070416 73514.78218820241 67881.17352860802 79299.63596453864 85506.54489702039 58653.34719720306 74454.77911555205 0.45979924147325657 1.0208961007653898 0.772343511353494 0.864590289775744 0.9873749282649703 0.9117100921521512 1.065071133197071 1.1484359488101665 0.7877714217132316 1.0 16.18407683527448 -4.7564412744815625 24.99999619183424 0.9507533312488277 0.4597984867115646 0.6287427791909506 0.11321441075098491 105.26159571199207 526447.5226224717 0.02889009438163636 0.23407843913749732 1.752099337945448e-05 4.7564412744815625 -0.49095484453726307 S(ph)PPSTGSTYGSSQKEESAASGGAAYTKR ddPTM_PC-9_AZD4547_30min_R2 1 SPPSTGSTYGSSQKEESAASGGAAYTKR 28 2 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.65)PPS(0.161)T(0.161)GS(0.012)T(0.012)Y(0.003)GSSQKEESAASGGAAYTKR 59.55 0.0051581000000000005 8024000.0 6694.7 3491.5 8002.0 9312.6 8172.3 7089.1 5669.1 6671.3 5758.1 8313.3 True False 8823.475341589468 4620.059094996171 7895.8882515860805 7165.723948235745 7037.717209166245 6645.817456333963 6173.638917498088 5640.403876223087 6062.461410605866 8022.253897371588 1.099874854930781 0.5759053695009437 0.984248111889489 0.8932307603208026 0.8772743046031095 0.8284227277463007 0.7695641395145595 0.7030946599771803 0.7557055022394855 1.0 12.96979191158269 -6.984433376186447 3.309193924228023 0.7830703234678705 0.8744829427930904 0.05167977949641489 0.14381297876844848 0.6741744525869916 15.446590216734277 0.053328302934377125 0.043903757059566624 1.0364935976086473e-07 6.984433376186447 0.09141261932521982 S(ph)PPSTGSTYGSSQKEESAASGGAAYTKR ddPTM_PC-9_Lapatinib_30min_R1 1 SPPSTGSTYGSSQKEESAASGGAAYTKR 28 2 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.349)PPS(0.349)T(0.083)GS(0.083)T(0.103)Y(0.021)GS(0.006)S(0.006)QKEESAASGGAAYTKR 65.197 0.00086622 10064000.0 11942.0 6760.9 6381.5 3876.4 5054.1 5052.2 3408.0 4415.8 5993.4 4874.0 True False 11771.704890105415 6745.2455514384565 5856.8377033023635 4161.483387291323 4756.827774742912 4836.129183253424 3584.44956452793 4620.974188670456 5318.360178700061 5716.4644058032345 2.0592632183898543 1.1799680838720565 1.0245559645847921 0.72798203432644 0.8321275944469942 0.8460000517704418 0.627039601766622 0.8083622779106855 0.9303583126138201 1.0 12.480907410461334 -4.199285777781104 1.143134777273566 0.8102767918336906 4.999937203246596 0.9215266413019441 0.10709170079418033 1.2502970171033498 0.5395228628907154 0.03200037239834676 8.682479133432661 6.319958437736027e-05 4.199285777781104 4.1896604114129055 up S(ph)PPSYSVLYPSSDPK ddPTM_PC-9_AZD4547_30min_R2 1 SPPSYSVLYPSSDPK 15 0 Q8N3V7-2;Q8N3V7-3;Q8N3V7 Q8N3V7-2 SYNPO Synaptopodin 1 S(0.994)PPS(0.005)YSVLYPSSDPK 105.19 0.0049532 0.0 8219.7 10151.0 10772.0 16079.0 11506.0 12785.0 12265.0 13743.0 12535.0 12870.0 True False 10833.393619618942 13432.112236375799 10629.156241700239 12372.23496807364 9908.590508016936 11985.551928909132 13356.561239546669 11619.33513272284 13197.574509290302 12419.425217323127 0.8722942833544404 1.0815405706248091 0.855849288973072 0.9962002871772468 0.7978300392031046 0.965064946177315 1.0754572780805014 0.9355775270916492 1.0626558216946933 1.0 13.60031078536983 -7.003672114699026 24.986107721046974 1.0140836965057218 0.9253814326147741 0.242087079900842 0.0811238842307766 238.0698035700001 1619904.3150271357 0.027734157226799092 0.023943371305708352 9.915802894243161e-08 7.003672114699026 -0.08870226389094771 S(ph)PPTQVAISSDSAR ddPTM_PC-9_AZD4547_30min_R2 4 SPPTQVAISSDSAR 14 0 Q6ZUT6;Q6ZUT6-4;H0YM82;Q6ZUT6-3 Q6ZUT6 C15orf52 Uncharacterized protein C15orf52 1 S(1)PPTQVAISSDSAR;S(1)PPTQVAISSDSAR;S(0.999)PPT(0.001)QVAISSDSAR;S(0.999)PPT(0.001)QVAISSDSAR 120.9 8.0006e-05 191474700.0 11043.300000000001 14334.0 20331.5 20562.3 15918.93 20357.1 16822.8 15209.7 17071.4 17583.0 True False 14554.839685090452 18967.185183352463 20061.891025633893 15821.979419368161 13708.861350233452 19084.167318889027 18319.99660991811 12859.390349135901 17973.759352046163 16967.42452184868 0.8578107812619657 1.117858821704421 1.1823769128779986 0.9324915162577828 0.8079518098094836 1.1247533350930574 1.079715815816817 0.7578869929597783 1.05930981622471 1.0 14.050479974981618 -5.829999838743966 24.99989931775948 0.9606929649362965 1.0592162541995254 0.08035613479518444 0.13295863680913705 118.75538664860085 43301.097314067556 0.03804118352948585 0.0564242162643943 1.4791089373697448e-06 5.829999838743966 0.09852328926322884 S(ph)PPTQVAISSDSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SPPTQVAISSDSAR 14 0 Q6ZUT6;Q6ZUT6-4;H0YM82;Q6ZUT6-3 Q6ZUT6 C15orf52 Uncharacterized protein C15orf52 1 S(1)PPTQVAISSDSAR;S(1)PPTQVAISSDSAR;S(1)PPTQVAISSDSAR;S(1)PPTQVAISSDSAR;S(0.997)PPT(0.003)QVAISSDSAR;S(1)PPTQVAISSDSAR 131.72 1.5490999999999998e-05 184089100.0 8808.099999999999 13423.9 15524.4 17164.7 17118.0 8557.84 20777.8 14090.599999999999 10784.91 11179.2 True False 10299.137362095118 14756.536076535554 15894.560572614862 16203.01750770823 13763.850782591184 8109.051805183686 18809.576365754856 13720.73668022477 10942.61890570483 13205.900465501498 0.7798890646647022 1.1174199074939923 1.2035953636131893 1.2269528723191778 1.042250077421623 0.6140476241182803 1.424331223371867 1.038985316909529 0.8286158853226887 1.0 13.688895056883458 -6.52131233826993 24.999977006787056 0.9909752865332789 1.0983618840586928 0.041725705932773915 0.2209109971797825 224.39456316740453 3581435.056745467 0.07380539238521118 0.07486080578500198 3.010839893128228e-07 6.52131233826993 0.10738659752541391 S(ph)PPTQVAISSDSAR ddPTM_PC-9_Lapatinib_30min_R1 3 SPPTQVAISSDSAR 14 0 Q6ZUT6;Q6ZUT6-4;H0YM82;Q6ZUT6-3 Q6ZUT6 C15orf52 Uncharacterized protein C15orf52 1 S(1)PPTQVAISSDSAR;S(1)PPTQVAISSDSAR;S(1)PPTQVAISSDSAR 153.41 0.00012877 177853000.0 1460.5 2689.7 928.48 1655.6 3394.7 5127.6 1316.1 1756.7 3711.0 1689.3 True False 1439.673002177103 2683.472164904676 852.1439584364464 1777.3583469196958 3195.0304202369884 4908.304501019405 1384.2412182732428 1838.3226951486452 3293.0281014375714 1981.2932541492412 0.7266329702390737 1.3544043312543086 0.4300948164295615 0.8970698018567099 1.6125984447511386 2.4773235818273704 0.6986553935790943 0.9278397790427106 1.6620599169463097 1.0 10.952226716123818 -6.215109782899352 9.013092671290714 1.4118085991219471 0.8567443423547577 0.2145249200118583 0.5097862882545918 0.7562915046003137 141.50652977997652 0.15794336985210933 0.20354333430460328 6.093828352532301e-07 6.215109782899352 -0.5550642567671894 S(ph)PPVDCPR ddPTM_PC-9_AZD4547_30min_R2 2 SPPVDCPR 8 0 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(1)PPVDCPR;S(1)PPVDCPR 124.92 0.0033912 12091600.0 11222.4 7347.1 16838.1 20860.0 17212.2 17346.4 14803.3 18854.2 17236.2 8820.1 True False 14790.889759579017 9721.906394628768 16614.81579218091 16051.049283787299 14822.583134198605 16261.72686582945 16120.765022208 15940.7166164144 18147.27034360029 8511.310983629503 1.7377921906540061 1.142233718557306 1.9520865615341207 1.8858492322345628 1.7415158678502156 1.9106018916600456 1.8940401840814394 1.8728861684262834 2.1321357401350287 1.0 13.055165649700553 -5.27884894667982 24.934750580622243 1.8382943031683485 1.4400129049650696 0.1618455191507715 0.3163121842825141 995.5518036832759 1425872.4165059763 0.07559166608637269 0.15792346615250405 5.262002539199235e-06 5.27884894667982 -0.3982813982032789 S(ph)PPVDCPR ddPTM_PC-9_Lapatinib_30min_R1 2 SPPVDCPR 8 0 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(1)PPVDCPR;S(1)PPVDCPR 115.7 0.0036225000000000003 13330000.0 10771.1 10740.7 13116.9 12429.900000000001 14550.5 10955.3 10514.099999999999 13424.3 13837.8 10778.7 True False 10617.502138822174 10715.830569056643 12038.479114698233 13344.036310930864 13694.668197383657 10486.767357051618 11058.468652113588 14048.041985816566 12279.241245506017 12641.783933285045 0.839873723111731 0.8476517733262721 0.9522769237497923 1.0555501012635433 1.0832860512135816 0.8295322410502999 0.8747553913650838 1.1112388931777997 0.9713218727916654 1.0 13.625912441965134 -5.322806877949211 3.7172320563466212 0.9873702554922015 0.8409954251380021 0.32709765121401835 0.08211757954243967 0.2805217987330975 7.7192346777451615 0.023610530611963828 0.05712964657955429 4.755466449932413e-06 5.322806877949211 -0.1463748303541994 S(ph)PPVQPHTPVTISLGTAPSLQNNQPVEFNHAINYVNK ddPTM_PC-9_AZD4547_30min_R2 2 SPPVQPHTPVTISLGTAPSLQNNQPVEFNHAINYVNK 37 0 Q96ST3 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 S(0.952)PPVQPHT(0.043)PVT(0.004)IS(0.001)LGTAPSLQNNQPVEFNHAINYVNK;S(0.798)PPVQPHT(0.088)PVT(0.075)IS(0.028)LGT(0.009)APS(0.002)LQNNQPVEFNHAINYVNK 59.434 0.00013843 76884000.0 102840.0 92376.0 137456.0 174399.0 146634.0 143992.0 117103.0 154021.0 121323.0 137071.0 True False 135540.9807951155 122234.73548886334 135633.2436278452 134194.00498769036 126276.40018708084 134988.15747731592 127524.94014142976 130220.59350048065 127735.8860941864 132272.1860111653 1.0247126390099448 0.9241151838115484 1.0254101615618283 1.0145292750840518 0.9546708495195027 1.0205332016356135 0.9641100218201972 0.9844896151447028 0.9657048087449316 1.0 17.013150200283214 S(ph)PPVQPHTPVTISLGTAPSLQNNQPVEFNHAINYVNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPPVQPHTPVTISLGTAPSLQNNQPVEFNHAINYVNK 37 0 Q96ST3 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 S(0.969)PPVQPHT(0.024)PVT(0.007)ISLGTAPSLQNNQPVEFNHAINYVNK;S(0.875)PPVQPHT(0.066)PVT(0.053)IS(0.004)LGT(0.001)APSLQNNQPVEFNHAINYVNK;S(0.579)PPVQPHT(0.25)PVT(0.08)IS(0.038)LGT(0.038)APS(0.016)LQNNQPVEFNHAINYVNK 78.079 3.3363999999999998e-09 85183100.0 137358.9 145351.8 185719.3 213217.4 227184.0 207569.8 198840.0 169791.6 174149.7 150351.3 True False 160611.04880806123 159781.36610741878 190147.55245636762 201271.52033813723 182668.92605398945 196684.47428225083 180004.4357230645 165334.75040907098 176696.30990363614 177608.80050976443 0.9042966809475822 0.8996252755990797 1.0705975824993752 1.1332294332288555 1.0284902861215304 1.1074027509770703 1.0134882686354743 0.9308927819710225 0.994862357025613 1.0 17.438343543384036 -5.253315583929051 24.681185892953707 1.0375140681787316 0.9019609525995356 0.48126195154122375 0.055140304230272705 468.0580963805835 1422013.6689462075 0.015712132137632926 0.040014803619701333 5.5806452483667985e-06 5.253315583929051 -0.13555311557919603 S(ph)PPVQPHTPVTISLGTAPSLQNNQPVEFNHAINYVNK ddPTM_PC-9_Lapatinib_30min_R1 2 SPPVQPHTPVTISLGTAPSLQNNQPVEFNHAINYVNK 37 0 Q96ST3 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 S(0.963)PPVQPHT(0.029)PVT(0.007)IS(0.001)LGTAPSLQNNQPVEFNHAINYVNK;S(0.908)PPVQPHT(0.074)PVT(0.016)IS(0.001)LGTAPSLQNNQPVEFNHAINYVNK 71.623 1.377e-06 46673000.0 184010.0 148456.0 187314.0 141911.0 163629.0 196722.0 132194.0 163030.0 193348.0 125816.0 True False 181385.98365669925 148112.25925310908 171913.7659729501 152347.60834121812 154004.6639269915 188308.65864138014 139038.35848979015 170604.96897027598 171571.11219529825 147563.12796071774 1.229209397790655 1.0037213313378497 1.165018445656117 1.0324232784071508 1.0436527475074162 1.2761227092685994 0.9422296776387328 1.1561490416202895 1.162696363016726 1.0 17.170972750349506 -11.318896361466653 2.4234769543121515 0.9655971567083271 1.1074407713887993 0.10047562754260586 0.09988544739245069 15866819.81805723 10054666.893293904 3209548.706591818 0.023022513669707218 4.7984794422880005e-12 11.318896361466653 0.14184361468047213 S(ph)PQALSNGTK ddPTM_PC-9_AZD4547_30min_R2 1 SPQALSNGTK 10 0 Q8NC74 Q8NC74 RBBP8NL RBBP8 N-terminal-like protein 1 S(1)PQALSNGTK 70.54 0.035508 19116000.0 37856.0 38144.0 42942.0 52078.0 56389.0 48287.0 44003.0 42424.0 39945.0 38461.0 True False 49893.420546284535 50473.302053425155 42372.56102219566 40072.22169707935 48560.360694991075 45267.60625664727 47919.18175489379 35868.345606536684 42056.41115066627 37114.49209661727 1.344311015125867 1.3599351412928387 1.1416715851018644 1.0796920403157466 1.3083935129322979 1.2196746796050888 1.2911178099958773 0.9664242612606259 1.133153352636056 1.0 15.179695005572889 -1.5228787540138229 0.08781774978657701 0.8437179482000844 2.1745064048326532 0.43844236235253586 0.10090780830972829 168.37463119908205 1.070627769715096 2.190508842623341 27.015854342407295 0.02999999939671221 1.5228787540138229 1.3307884566325687 S(ph)PQALSNGTK ddPTM_PC-9_Lapatinib_30min_R1 2 SPQALSNGTK 10 0 Q8NC74 Q8NC74 RBBP8NL RBBP8 N-terminal-like protein 1 S(0.995)PQALS(0.005)NGTK;S(1)PQALSNGTK 106.26 0.0023421999999999996 20173900.0 102834.0 91275.0 94357.0 71531.0 77787.0 86247.0 86043.0 78718.0 88593.0 68651.0 True False 101367.56830255424 91063.65834541948 86599.33168855314 76791.62836042073 73211.72159512618 82558.41686157673 90497.8855283676 82375.52565418746 78614.7234143515 80517.23387829249 1.258954927038086 1.130983442415181 1.0755378385136052 0.9537290920412979 0.9092677190797548 1.0253508830962776 1.1239567129834784 1.0230794289170926 0.9763713881823514 1.0 16.297009989729496 -4.994988377070553 1.6268622831299377 1.0065886874295544 1.2897262868360926 0.6822726557937465 0.054829355000721815 0.4359644589034747 1.5279109266617714 0.017628379023650626 0.17261005976995916 1.0116065273046882e-05 4.994988377070553 0.28313759940653815 S(ph)PQFINLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPQFINLK 8 0 Q92576-2;Q92576 Q92576-2 PHF3 PHD finger protein 3 1 S(1)PQFINLK;S(1)PQFINLK 75.21300000000001 0.02669 17282400.0 78541.0 87577.0 83748.0 94370.0 88712.0 82995.0 80424.0 74731.0 76710.0 73573.0 True False 91836.44004453982 96271.06578377014 85744.86993605863 89082.75485166787 71329.52042442032 78642.59609565265 72805.65650066262 72769.39043403947 77831.73862893773 86911.20249645234 1.0566697664583402 1.1076945551144557 0.9865801815313587 1.0249858740051856 0.8207172191333095 0.9048614429061983 0.8377016358004539 0.8372843585613703 0.8955317196550672 1.0 16.407254526030307 -6.162499452825872 5.017957493800566 0.8736931345379786 1.048176449006014 0.670697092153992 0.05523959914228444 0.12610274975523125 5.014548504008858 0.016020624341801622 0.02088999759809037 6.878607789543678e-07 6.162499452825872 0.17448331446803533 S(ph)PQISMSDIDLNLK ddPTM_PC-9_AZD4547_30min_R2 1 SPQISMSDIDLNLK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(1)PQISMSDIDLNLK 87.647 0.024975 0.0 9711.8 16014.0 10786.0 8174.1 11242.0 11967.0 18616.0 24946.0 18204.0 10663.0 True False 12799.950382010931 21190.212329161874 10642.970592552798 6289.68753358609 9681.242351045223 11218.701598221007 20272.787936029417 21091.168902052257 19166.226275797424 10289.691615564601 1.243958600532713 2.0593632074559656 1.0343332910438066 0.6112610337196166 0.9408680758129803 1.0902855029446312 1.9702036458861394 2.049737707410872 1.8626628466499249 1.0 13.328912124525498 -7.256538482478404 24.707408973133795 1.8081292035671257 1.1630015579646371 0.2706451592979857 0.4388976995632882 446.5525574876392 2251259.8553698347 0.18208130310699205 0.13644902414804017 5.5393845773075476e-08 7.256538482478404 -0.6451276456024886 S(ph)PQISMSDIDLNLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPQISMSDIDLNLK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(1)PQISMSDIDLNLK;S(0.956)PQIS(0.04)MS(0.005)DIDLNLK;S(0.986)PQIS(0.012)MS(0.001)DIDLNLK 100.55 0.008456299999999998 10457800.0 94652.0 174494.0 133489.0 91451.0 114250.0 67006.0 97918.0 59136.0 64277.0 59898.0 True False 110674.7141377854 191816.6111293283 136671.88401985148 86327.2969581424 91863.53265048718 63492.08740267849 88642.49817507053 57583.74265977126 65216.929524862964 70757.0332476928 1.5641514215322787 2.7109193577669246 1.931566061304697 1.2200525233434274 1.2982954263911652 0.8973254599357979 1.252772962721143 0.813823587800707 0.921702430577663 1.0 16.110585938479886 -5.760645507834694 2.854714225040248 1.0391546917080328 2.1804521445824734 0.7168627563550494 0.2944577595132044 0.12519688918053629 2.0864561022171944 0.08224292759812585 0.1456546427756906 1.7352197901911282e-06 5.760645507834694 1.1412974528744406 S(ph)PQISMSDIDLNLK ddPTM_PC-9_Lapatinib_30min_R1 2 SPQISMSDIDLNLK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(1)PQISMSDIDLNLK;S(1)PQISMSDIDLNLK 169.94 0.00028775 5256700.0 16867.9 29219.3 22227.0 22949.0 29308.0 25174.9 38850.0 26556.0 22688.9 21566.1 True False 16627.36065280598 29151.644506078446 20399.5818587012 24636.746015619774 27584.161061744984 24098.22821255822 40861.46290549005 27789.888707444294 20133.437157291006 25293.771649978073 0.6573697621256256 1.1525226411263074 0.8065061288998743 0.9740242126223644 1.0905515177199323 0.9527336826644875 1.6154752826483065 1.0986850475290182 0.7959839851447563 1.0 14.62649455830662 -6.2829345858670775 1.716316122091915 1.1295563398387287 0.8961021029997799 0.1463738863625712 0.2295540928281916 0.7157299960667167 4.168771917148897 0.08400470626735831 0.1102511230870989 5.212732202026382e-07 6.2829345858670775 -0.23345423683894884 S(ph)PQISMSDIDLNLKGPK ddPTM_PC-9_Lapatinib_30min_R1 1 SPQISMSDIDLNLKGPK 17 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(0.573)PQIS(0.093)MS(0.334)DIDLNLKGPK 61.958999999999996 0.014358000000000001 6226400.0 22504.0 15367.0 15130.0 13671.0 16819.0 17047.0 16050.0 12519.0 17592.0 12815.0 True False 22183.088833271828 15331.418655645663 13886.069803488956 14676.410945119102 15829.73948742625 16317.939548497907 16880.99046674686 13100.678442856428 15610.603708027422 15030.055675085847 1.4759152802103725 1.0200506895699237 0.9238867841658639 0.9764708303407715 1.0532056453833352 1.08568723238643 1.1231488978932505 0.8716320635173962 1.0386258072153323 1.0 13.875562732916933 -4.761817927418687 7.066047764949738 1.0091382943017908 1.4854679994085844 0.7993698366685753 0.06999850792452135 0.04801526436529948 14.293681900366337 0.018252009886196248 0.10992064856340619 1.7305417153316584e-05 4.761817927418687 0.4763297051067936 S(ph)PQLSDFGLER ddPTM_PC-9_AZD4547_30min_R2 2 SPQLSDFGLER 11 0 Q8IX90;Q8IX90-3 Q8IX90 SKA3 Spindle and kinetochore-associated protein 3 1 S(1)PQLSDFGLER;S(1)PQLSDFGLER 193.45 0.0001538 97335000.0 66172.0 59797.0 78336.0 86753.0 92586.0 77993.0 75282.0 72512.0 69198.0 68476.0 True False 87213.31953689615 79125.21085593192 77297.21345616684 66753.43617048896 79732.03205069136 73116.08538063416 81981.95215944163 61306.93655999413 72855.66500948307 66078.67608247222 1.3198406007415457 1.19743940930621 1.1697754561500726 1.0102114649993075 1.2066227227551973 1.106500458474359 1.2406718327274093 0.927786998690432 1.1025593932686024 1.0 16.01189716151889 -1.5228787452803376 0.30525419888842165 1.051066993773345 3.1723692546779585 0.41663840451466094 0.08831468392771663 58.55306623960729 0.8354803317841302 0.08858689849857201 68.22852001918169 0.029999999999999995 1.5228787452803376 2.1213022609046135 S(ph)PQLSDFGLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPQLSDFGLER 11 0 Q8IX90;Q8IX90-3 Q8IX90 SKA3 Spindle and kinetochore-associated protein 3 1 S(1)PQLSDFGLER;S(1)PQLSDFGLER;S(1)PQLSDFGLER;S(1)PQLSDFGLER 157.33 0.00027304 80932000.0 66706.4 78074.0 86887.0 89177.0 88119.0 94130.0 89495.0 73371.5 81387.6 71251.0 True False 77998.47600854444 85824.67074690925 88958.71560078248 84180.70180573469 70852.71451753443 89193.65709360539 81017.38571230987 71445.57586853014 82577.7396797879 84168.24227739446 0.9266972185481048 1.019679969840117 1.0569154492688584 1.0001480312289184 0.8417986713328781 1.0597067810879144 0.9625647812069039 0.8488424367122454 0.9811032931831377 1.0 16.36098836876235 -6.035671197486604 24.95601257063083 0.9452322066639295 1.0072185170761523 0.11795452426530806 0.06840272563175277 1102.7024975566976 771461.939234794 0.020140682637230154 0.026014216062414375 9.211467040913279e-07 6.035671197486604 0.0619863104122228 S(ph)PQLSDFGLER ddPTM_PC-9_Lapatinib_30min_R1 3 SPQLSDFGLER 11 0 Q8IX90;Q8IX90-3 Q8IX90 SKA3 Spindle and kinetochore-associated protein 3 1 S(1)PQLSDFGLER;S(1)PQLSDFGLER;S(1)PQLSDFGLER 159.41 0.00018864 83023900.0 94350.4 86619.0 88453.6 78005.3 104743.5 93976.6 94186.2 91902.7 116647.6 74042.5 True False 93004.94599425548 86418.43902735555 81181.2864487702 83742.06998005255 98582.69326364415 89957.43988815442 99062.70057938407 96172.83494930138 103509.51893431671 86840.64746957048 1.0709840230848695 0.9951381242020002 0.934830506384889 0.9643188117568596 1.135213706210426 1.0358909394322062 1.1407411559672707 1.1074633567535406 1.191947802676012 1.0 16.406082862039312 -6.259651489823439 24.996088573056788 1.1058933182742254 0.9875559272056846 0.4481596515031506 0.059944389378356014 144.7133171053175 2023205.7303962626 0.017900513933502126 0.02194373518746971 5.499820432960971e-07 6.259651489823439 -0.1183373910685408 S(ph)PQNQYPAELMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPQNQYPAELMR 12 0 P33993;P33993-2;C9J8M6 P33993 MCM7 DNA replication licensing factor MCM7 1 S(0.999)PQNQY(0.001)PAELMR 81.992 0.011095 18887000.0 27772.0 33738.0 31135.0 30782.0 32110.0 28356.0 32185.0 20270.0 22812.0 24117.0 True False 32473.251077997003 37087.285673325685 31877.376480145027 29057.38433659051 25818.276003563675 26868.961442114924 29136.203800778723 19737.93397784029 23145.582343935992 28489.22118993304 1.1398434117065916 1.3018006152597412 1.1189276206472512 1.0199430915597734 0.9062471673562923 0.9431272712926722 1.0227097331489814 0.6928211145629665 0.8124329615621336 1.0 14.798128562784433 -5.89609765428903 1.1015400981453691 0.8731533776385388 1.239316494295793 0.6459763770042517 0.09723885967603053 0.3352850964987534 0.8136278254133826 0.03890932442111762 0.09043401305296743 1.2702884394510707e-06 5.89609765428903 0.3661631166572542 S(ph)PQNQYPAELMR ddPTM_PC-9_Lapatinib_30min_R1 3 SPQNQYPAELMR 12 0 P33993;P33993-2;C9J8M6 P33993 MCM7 DNA replication licensing factor MCM7 1 S(1)PQNQYPAELMR;S(1)PQNQYPAELMR;S(0.998)PQNQY(0.002)PAELMR 88.28200000000001 0.0081198 19340900.0 29310.5 33749.7 40178.0 32329.7 34046.8 36528.3 37998.6 39036.8 36330.3 32822.8 True False 28892.526895112598 33671.55464322536 36874.71993156508 34707.33398671762 32044.23416258426 34966.06976062627 39965.981579422245 40850.59223884476 32238.399038980715 38496.177246368126 0.7505297658571651 0.8746726831532879 0.9578800434020752 0.9015787142862877 0.832400421410867 0.9082997913494151 1.0381805269559015 1.061159708856514 0.8374441657586198 1.0 15.232427569732904 -7.065908236072879 5.553319116146868 0.9884321617368484 0.8711615572233884 0.36726066215247755 0.07433276267400203 0.255497691107255 15.320581368263682 0.029054319270796956 0.02266991194688966 8.591950453005239e-08 7.065908236072879 -0.11727060451346005 S(ph)PQNSHSHSTPSSSVR ddPTM_PC-9_Lapatinib_30min_R1 1 SPQNSHSHSTPSSSVR 16 0 Q9UKI8-5;Q9UKI8;Q9UKI8-2;B3KRP1;Q9UKI8-4;C9JWT6 Q9UKI8-5 TLK1 Serine/threonine-protein kinase tousled-like 1 1 S(0.5)PQNS(0.5)HSHSTPSSSVR 57.159 0.033249 4460500.0 27752.0 37445.0 40126.0 30075.0 37574.0 32520.0 38962.0 39197.0 40055.0 32284.0 True False 27356.25139090649 37358.29840311393 36826.99517083923 32286.815827258924 35363.971193326244 31129.195407822597 40979.26171746988 41018.23571568362 35543.58410215087 37864.24638427404 0.7224823944275891 0.9866378436262699 0.9726060515530133 0.8526992852198543 0.9339673853383169 0.822126369343279 1.0822679871027245 1.0832972958024991 0.9387109871784745 1.0 15.20854859444737 -7.266480543505268 24.94856077383001 1.0330105110659635 0.8917031156544929 0.42238412947426474 0.08202389574141349 418.2735400787265 2070012.2709626954 0.03309770096620288 0.023069030226588322 5.4140150225376715e-08 7.266480543505268 -0.14130739541147064 S(ph)PQPDPVDTPASTK ddPTM_PC-9_AZD4547_30min_R2 2 SPQPDPVDTPASTK 14 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(1)PQPDPVDTPASTK;S(1)PQPDPVDTPASTK 132.59 0.00023473 3861700.0 28803.0 54057.0 31861.0 29134.0 31390.0 25449.0 24737.0 27357.0 24901.0 24210.0 True False 37961.7548603823 71529.86810774969 31438.50232239242 22417.606415813003 27032.04033084057 23857.670006946293 26938.545078081188 23129.604251320598 26217.216023600973 23362.415268950488 1.624907117837036 3.0617497071381794 1.3456871629268294 0.9595585969061524 1.1570738735548096 1.0211987815597994 1.153071922057798 0.9900348052652199 1.1221963021282573 1.0 14.511901811148064 -5.433630602889665 6.2476653660060775 1.0697006703142127 2.3340715983950036 0.7040056656917768 0.32850156460590185 0.10690481810098858 6.120706249428494 0.07780508805165777 0.16347137440669515 3.684422256725671e-06 5.433630602889665 1.2643709280807909 S(ph)PQPDPVDTPASTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPQPDPVDTPASTK 14 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(1)PQPDPVDTPASTK 120.59 0.001301 0.0 7998.4 9845.0 6235.1 8175.2 12242.0 4400.9 9205.9 9070.6 7920.0 5480.8 True False 9352.371144399085 10822.346536661671 6383.7684307484315 7717.170048356007 9843.267979932316 4170.109056658324 8333.850507055735 8832.506361095124 8035.815016832065 6474.425654011075 1.444509774948925 1.671553140772718 0.9859976423999125 1.1919466622610795 1.520330683515403 0.6440894188158348 1.287195336298703 1.3642146551830674 1.2411626059608345 1.0 12.660536501729743 -5.255232162590782 24.95879000068121 1.1683067051156555 1.558031474865586 0.3224948218902508 0.2333332508940899 581.3677247285023 2337622.6314357454 0.05935238947173019 0.1488663149074271 5.556071646569741e-06 5.255232162590782 0.3897247697499304 S(ph)PQPDPVDTPASTK ddPTM_PC-9_Lapatinib_30min_R1 2 SPQPDPVDTPASTK 14 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(0.988)PQPDPVDT(0.01)PAS(0.001)T(0.001)K;S(1)PQPDPVDTPASTK 108.14 0.00071407 8856000.0 37656.0 54669.0 22691.0 21296.0 22880.0 24893.0 46452.0 36559.0 16719.3 18755.6 True False 37119.01853473535 54542.417289353325 20825.433569792996 22862.178881373427 21534.243383810746 23828.3844184172 48857.0572686184 38257.66460519118 14836.196371965829 21997.480469733924 1.687421365633531 2.479484746646217 0.9467190389575054 1.0393089750814521 0.978941357099485 1.0832324388787342 2.221029691824946 1.7391839332613321 0.6744498031208064 1.0 14.425050670482168 -5.265174002893242 24.99654978277686 1.2539389996787618 2.0834530652682486 0.36122814119623525 0.46151022963815364 349.1209806581958 2336749.9236685387 0.1272362299169106 0.2820285517938632 5.430327183302855e-06 5.265174002893242 0.8295140655894868 S(ph)PQPDPVGTPTIFKPQSK ddPTM_PC-9_AZD4547_30min_R2 2 SPQPDPVGTPTIFKPQSK 18 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(0.987)PQPDPVGT(0.013)PTIFKPQSK;S(1)PQPDPVGTPTIFKPQSK 97.77600000000001 0.00035473 17019100.0 68158.0 139306.0 96236.0 87590.0 89613.0 80052.0 73105.0 88318.0 72216.0 77300.0 True False 89830.82622552998 184333.94022269404 94959.84776051466 67397.47875201014 77171.78178297602 75046.33578514133 79611.20337684946 74670.48244574071 76033.19032811404 74593.75052828899 1.2042674565808629 2.471171363783178 1.273026856646684 0.9035271490531941 1.0345609549919244 1.0060673347786784 1.0672637159685066 1.0010286641562904 1.0192970562497612 1.0 16.18676714596134 -5.496182511440024 12.945020862514435 1.0146060326767832 1.8464862531314763 0.5700049340521303 0.2861256930259543 1.1761156453943806 568.5238518683344 0.06785409632132575 0.13791042269135367 3.190196899100592e-06 5.496182511440024 0.8318802204546931 S(ph)PQPDPVGTPTIFKPQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPQPDPVGTPTIFKPQSK 18 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(0.986)PQPDPVGT(0.013)PT(0.001)IFKPQSK 62.94 0.0091498 6412600.0 19862.0 28447.0 20177.0 28218.0 33803.0 19871.0 37869.0 24416.0 23917.0 16502.0 True False 23224.24430761834 31271.030160326507 20658.09620169861 26637.036943990337 27179.54480686587 18828.929779103735 34281.77417218235 23775.105870890402 24266.74087848138 19493.681970239868 1.1913728942061206 1.604162323365416 1.0597329038832377 1.3664446247074262 1.3942745576930857 0.9658990952991343 1.758609493297305 1.2196313609294946 1.244851583991589 1.0 14.250718992388052 -8.674739446520435 2.036591402621085 1.001736577803353 1.3269264149100375 0.15669301220306042 0.22362277834952982 1.0525592451148067 8.657364828169682 0.2025499952834179 0.0560938806581123 2.114757400747748e-09 8.674739446520435 0.3251898371066846 S(ph)PQPDPVGTPTIFKPQSK ddPTM_PC-9_Lapatinib_30min_R1 2 SPQPDPVGTPTIFKPQSK 18 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(0.948)PQPDPVGT(0.051)PT(0.001)IFKPQSK;S(0.886)PQPDPVGT(0.112)PT(0.002)IFKPQSK 86.182 0.0008347999999999999 11436700.0 41296.0 96489.0 44137.0 24222.0 31988.0 53756.0 117772.0 88540.0 36934.0 29780.0 True False 40707.111467241084 96265.5856487664 40508.226233746995 26003.36668222329 30106.52873082772 51456.98119135645 123869.6578971784 92653.8916311611 32774.10398773785 34927.43332064428 1.165476749852691 2.7561597431170948 1.1597825085476325 0.7444969243375146 0.8619736942718002 1.4732540097912714 3.5464861319759144 2.652754091048451 0.938348480601531 1.0 15.092073008207455 -7.03187857862128 24.880049971248216 2.2203757960233386 1.3529664315116197 0.11114576864640002 0.8792703578494334 1147.9402585459832 895921.4799409228 0.3448581688178066 0.26739624905710346 9.29226146352338e-08 7.03187857862128 -0.8674093645117189 S(ph)PQPPSR ddPTM_PC-9_AZD4547_30min_R2 1 SPQPPSR 7 0 E7ERS3;Q86VM9 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 S(1)PQPPSR 81.525 0.023815 252170000.0 109570.0 182130.0 170760.0 257970.0 208220.0 185230.0 178510.0 197150.0 176830.0 156360.0 True False 144410.9808024194 240999.960753731 168495.610827398 198499.00209676943 179312.24713882228 173647.53881828996 194397.04418030733 166684.99755630564 186176.8727944003 150885.88399228026 0.9570874158765432 1.597233315517184 1.116708908541893 1.3155571405667423 1.1883964383838344 1.1508534411819085 1.2883713110648125 1.1047090234420716 1.2338919179737557 1.0 17.20309831643842 -11.244117459958002 0.21577335513237195 0.764124302500069 1.2746356852933491 0.1390902718377881 0.16002627514769976 48.57946708627714 1.7310771249242782 6.308221130861532 0.3418408511789313 5.7001008562059205e-12 11.244117459958002 0.5105113827932801 S(ph)PQPPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPQPPSR 7 0 E7ERS3;Q86VM9 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 S(1)PQPPSR 83.99799999999999 0.027211000000000003 3082100.0 20695.0 23193.0 24891.0 21906.0 32118.0 23593.0 24460.0 16643.0 19856.0 19222.0 True False 24198.2547551184 25495.447762802865 25484.49583964317 20678.67784021024 25824.70846099216 22355.7415468972 22142.971724935447 16206.138884716122 20146.356436138572 22706.796438731737 1.065683343769385 1.1228113059275255 1.1223289867598152 0.9106823102944602 1.1373118410020224 0.9845396556585264 0.9751693412446965 0.7137131355558713 0.8872390471504057 1.0 14.470836559043503 -7.346890843736329 2.3560956102070585 0.8526678263215204 1.0650974333076835 0.44489760117248767 0.09307959673508165 0.24994144500575227 2.7106044774870552 0.04524874803220844 0.027851337547462555 4.49892917483229e-08 7.346890843736329 0.2124296069861631 S(ph)PQPPSR ddPTM_PC-9_Lapatinib_30min_R1 1 SPQPPSR 7 0 E7ERS3;Q86VM9 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 S(1)PQPPSR 100.25 0.015562999999999999 7684700.0 21140.0 21803.0 21293.0 16046.0 21495.0 19483.0 15292.0 17297.0 20476.0 16428.0 True False 20838.5397233988 21752.51649307234 19542.371733356937 17226.076367886835 20230.706360795968 18649.757507091254 16083.744935669352 18100.681765802987 18169.777258161062 19267.55791106597 1.0815350767120604 1.128971123038856 1.014263033413961 0.8940456516283961 1.0499880915980966 0.9679357183288965 0.8347578354199183 0.9394382956756129 0.9430244010179194 1.0 14.23388610671705 -5.48010459497666 4.078524645775795 0.9450111785218764 1.1025926609042285 0.5627834212939425 0.0554499424149752 0.15793481728121608 5.575293318992195 0.015590385798735862 0.032794740359792816 3.3105138185195787e-06 5.48010459497666 0.15758148238235203 S(ph)PQPPVEEEDEHFDDTVVCLDTYNCDLHFK ddPTM_PC-9_AZD4547_30min_R2 3 SPQPPVEEEDEHFDDTVVCLDTYNCDLHFK 30 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1W2PRI6 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 1 S(0.739)PQPPVEEEDEHFDDT(0.261)VVCLDTYNCDLHFK;S(0.99)PQPPVEEEDEHFDDT(0.01)VVCLDTYNCDLHFK;S(0.998)PQPPVEEEDEHFDDT(0.002)VVCLDTYNCDLHFK 92.664 1.4726e-09 10726000.0 36062.9 33598.1 56625.0 51117.4 44937.2 53968.4 55290.2 69923.0 53268.9 49630.1 True False 47530.152045081486 44458.02877834477 55874.11550188225 39333.073185957306 38698.44545253421 50593.74741651467 60210.92068868999 59118.00702069261 56084.585303385276 47892.56530522675 0.9924327866374343 0.9282866452236762 1.166655307473881 0.8212772261264671 0.808026156166474 1.0564008650209666 1.257208092841894 1.2343879815984877 1.1710499311521425 1.0 15.54751409334447 -7.008915793984516 7.784797324786976 1.1816208040989769 0.9463506451174245 0.4610030174353956 0.11286017699885695 0.12385736406149252 54.33964587436869 0.042573817559793406 0.03519159297362709 9.796799186194938e-08 7.008915793984516 -0.23527015898155235 S(ph)PQQSAALPR ddPTM_PC-9_AZD4547_30min_R2 4 SPQQSAALPR 10 0 E5RJN3;A0A0A6YYG7;Q6IBW4-2;Q6IBW4;Q6IBW4-4 E5RJN3 NCAPH2 Condensin-2 complex subunit H2 1 S(1)PQQSAALPR;S(1)PQQSAALPR;S(0.999)PQQS(0.001)AALPR;S(1)PQQSAALPR 130.56 0.00020883 189382400.0 46951.1 52268.0 69725.9 113349.0 57992.2 81276.0 49122.3 126241.5 113002.7 93720.2 True False 61880.57315645229 69162.60884355142 68801.28900790623 87218.13927459296 49940.984048237435 76193.798871648 53494.089537495565 106733.77691607595 118975.7920224156 90439.0843242089 0.6842237912827693 0.764742471248549 0.7607472977199237 0.9643854747791409 0.5522057683512961 0.8424875090343247 0.5914930468084822 1.1801731266257995 1.3155351241273894 1.0 16.464658764743596 -7.774561168180241 24.99351619352537 1.1858908671999924 0.7448240328107727 0.6875700246149281 0.1319378832281221 123.84074761315055 235880.156172711 0.06777853091673218 0.03287090854491014 1.6805012189463212e-08 7.774561168180241 -0.4410668343892197 S(ph)PQQSAALPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPQQSAALPR 10 0 E5RJN3;A0A0A6YYG7;Q6IBW4-2;Q6IBW4;Q6IBW4-4 E5RJN3 NCAPH2 Condensin-2 complex subunit H2 1 S(1)PQQSAALPR;S(1)PQQSAALPR 113.95 0.0012489 48383000.0 31757.6 28172.5 46982.0 42589.0 46061.0 37843.0 30842.0 38897.0 29297.0 31296.0 True False 37133.53443880878 30969.279614433806 48102.22906022722 40202.87640540097 37035.67770165514 35858.4464612059 27920.422483256694 37875.99496477818 29725.413200521343 36969.7170610003 1.0044311233850718 0.8376931736679042 1.3011251609217942 1.0874542626081216 1.001784180293996 0.9699410574887334 0.7552241321508573 1.0245140611242038 0.8040476250189904 1.0 15.174056381791031 -6.796227070659649 2.7031926676295934 0.8957718408245919 1.0559387516279712 0.2272775890655777 0.13036513410715667 0.4157692579928748 6.217593601620341 0.04997549454221321 0.04540300611047696 1.5987219190724338e-07 6.796227070659649 0.1601669108033793 S(ph)PQQSAALPR ddPTM_PC-9_Lapatinib_30min_R1 4 SPQQSAALPR 10 0 E5RJN3;A0A0A6YYG7;Q6IBW4-2;Q6IBW4;Q6IBW4-4 E5RJN3 NCAPH2 Condensin-2 complex subunit H2 1 S(1)PQQSAALPR;S(1)PQQSAALPR;S(1)PQQSAALPR;S(1)PQQSAALPR 130.69 0.00020482 172132000.0 131658.0 116255.8 96051.6 64321.7 132204.9 109675.5 75554.7 119140.8 143869.0 76295.8 True False 129780.5327768799 115986.61683783481 88154.60821789815 69052.13238890117 124428.86770683405 104984.93453107766 79466.55267401361 124676.51651287383 127664.95821226679 89483.42737223672 1.4503303749979723 1.2961798652989571 0.9851501088708762 0.7716750957879089 1.3905241602920493 1.1732332747421168 0.8880588842830693 1.393291698520213 1.4266882925840672 1.0 16.44933289475553 S(ph)PQSDPADTPTNTK ddPTM_PC-9_AZD4547_30min_R2 4 SPQSDPADTPTNTK 14 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(1)PQSDPADTPTNTK;S(1)PQSDPADTPTNTK;S(1)PQSDPADTPTNTK;S(0.993)PQS(0.007)DPADTPTNTK 233.14 2.5537999999999997e-75 10775600.0 51779.9 93353.0 74239.0 69254.0 62345.0 54277.399999999994 46719.9 63255.0 50420.1 63354.0 True False 68244.8311111728 123527.53163258682 73254.54235309904 53288.56026363401 53689.47290303461 50883.425597666974 50877.880591561036 53480.39320529604 53085.20355132572 61135.99574345682 1.1162790477404927 2.0205368397194636 1.1982227730532913 0.8716396881347485 0.8781974064564216 0.8322989587212678 0.8322082591908437 0.8747774949101056 0.8683133873223493 1.0 15.899734441911065 -5.534113720423471 4.48944138710004 0.8757504408135042 1.5832729505932663 0.6356652463742993 0.20827902856241182 0.10070880679586114 5.092341781627833 0.052186643735280154 0.10056945841948507 2.923386785999686e-06 5.534113720423471 0.7075225097797622 S(ph)PQSDPADTPTNTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPQSDPADTPTNTK 14 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(1)PQSDPADTPTNTK;S(0.995)PQS(0.005)DPADTPTNTK;S(1)PQSDPADTPTNTK;S(0.999)PQS(0.001)DPADTPTNTK 165.02 4.0127e-14 12991200.0 50993.6 77357.0 55213.0 68476.0 90281.0 61279.0 89077.0 72079.0 62125.0 41337.1 True False 59625.80931049074 85036.49172539746 56529.48731646857 64639.51172218737 72591.08613758122 58065.42136448578 80638.98169836779 70187.00262401332 63033.460596047 48831.18900569644 1.2210599521452374 1.7414380738400095 1.157651256656357 1.3237341346459288 1.486572160450835 1.189105212197723 1.6513827195352704 1.4373396194761017 1.2908442714490074 1.0 15.575515286579456 -8.636605280533294 3.444928887028384 1.000187127794743 1.404797835434407 0.3074522746129258 0.1816654914818458 0.6049198127344901 15.210334604182146 0.16680896195711617 0.044003536277637166 2.3088446869778316e-09 8.636605280533294 0.4046107076396641 S(ph)PQSDPADTPTNTK ddPTM_PC-9_Lapatinib_30min_R1 3 SPQSDPADTPTNTK 14 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(0.994)PQS(0.006)DPADTPTNTK;S(0.997)PQS(0.003)DPADTPTNTK;S(0.99)PQS(0.01)DPADTPTNTK 178.47 7.3365e-05 10682700.0 38631.0 66853.0 37309.0 16219.8 27907.699999999997 34057.3 67268.0 64081.0 28182.800000000003 22240.199999999997 True False 38080.11485594225 66698.20598593599 34241.598036904776 17412.658199666635 26266.223954649256 32600.74867044392 70750.80789514813 67058.43719919174 25008.55628595924 26084.388936796277 1.459881423644318 2.5570162347888976 1.3127237950589452 0.6675509340800868 1.0069710284681606 1.249818377936209 2.712381266303793 2.57082645722227 0.9587556889508192 1.0 14.670899016166794 S(ph)PQTLAPVGEDAMK ddPTM_PC-9_AZD4547_30min_R2 1 SPQTLAPVGEDAMK 14 0 Q92797 Q92797 SYMPK Symplekin 1 S(1)PQTLAPVGEDAMK 67.416 0.030264999999999997 4336900.0 12061.0 16694.0 18441.0 15012.0 18794.0 17330.0 16776.0 19889.0 17018.0 17263.0 True False 15896.14711561542 22090.009031037116 18196.460290864663 11551.215333087974 16184.777508054083 16246.352360421999 18269.031500581717 16815.6120537528 17917.53673706441 16658.62762444826 0.9542290922144258 1.3260401474259345 1.0923144871885768 0.693407379857352 0.9715552729146335 0.9752515469268785 1.0966708610359968 1.0094236111667534 1.0755709978635075 1.0 14.023981932656534 -5.533373134989993 24.99956976857826 0.9732408556673972 1.1573953670699282 0.21430295870853144 0.13257560984633004 272.004116806207 647961.8872694648 0.036188073710046245 0.06276087286431367 2.9283761763102476e-06 5.533373134989993 0.18415451140253103 S(ph)PQTLAPVGEDAMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPQTLAPVGEDAMK 14 0 Q92797 Q92797 SYMPK Symplekin 1 S(0.997)PQT(0.003)LAPVGEDAMK;S(0.992)PQT(0.008)LAPVGEDAMK;S(0.998)PQT(0.002)LAPVGEDAMK 114.01 0.00015819 34400300.0 71500.0 114867.0 99801.0 92961.0 102125.0 74927.0 101514.0 58302.0 72833.0 65568.0 True False 83603.53781062881 126270.23663044357 102180.63433740025 87752.6965536283 82114.33936044667 70997.69621855498 91897.85902228505 56771.634276075165 73898.04483850142 77454.95936399774 1.0793826308491878 1.630240822114948 1.3192264920985213 1.1329512954907972 1.0601559930404494 0.916632024618372 1.1864683653168449 0.7329631923151392 0.9540776400284365 1.0 16.241069995850047 -6.01153549652552 1.7321202793224004 0.9600485811374735 1.3792000990418802 0.504728246123465 0.1634485211984172 0.27532054884164814 1.6617632352986966 0.05326612638364708 0.08737283430840992 9.737881906953849e-07 6.01153549652552 0.41915151790440675 S(ph)PQTLAPVGEDAMK ddPTM_PC-9_Lapatinib_30min_R1 3 SPQTLAPVGEDAMK 14 0 Q92797 Q92797 SYMPK Symplekin 1 S(0.967)PQT(0.033)LAPVGEDAMK;S(0.995)PQT(0.005)LAPVGEDAMK;S(0.999)PQT(0.001)LAPVGEDAMK 114.01 0.0013765999999999997 12403000.0 83470.0 113483.0 93364.0 88514.0 89674.0 100398.0 101152.0 98445.0 95099.0 65227.0 True False 82279.70249347661 113220.23708587483 85687.97231546225 95023.61483404809 84399.55162586735 96104.2115791689 106389.15561946279 103019.11409114132 84387.94918313438 76501.40004048585 1.075531983073941 1.4799760138501614 1.1200837144171834 1.2421160238081912 1.1032419221243226 1.2562412129491605 1.3906824654602377 1.3466304412288121 1.1030902589818594 1.0 16.223198530138838 -8.48727210455743 5.02437518450797 1.0005297713684322 1.2538837677959058 0.314287800705617 0.12294464475580215 0.1934600312759576 12.70907799768802 0.11631298830278666 0.03025934211356143 3.256326139467834e-09 8.48727210455743 0.2533539964274736 S(ph)PQTPELVEALAFR ddPTM_PC-9_AZD4547_30min_R2 1 SPQTPELVEALAFR 14 0 Q9NZB2-4;Q9NZB2;Q9NZB2-6;A0A0C4DG79 Q9NZB2-4 FAM120A Constitutive coactivator of PPAR-gamma-like protein 1 1 S(0.981)PQT(0.019)PELVEALAFR 74.475 0.018614 2622700.0 2097.5 2704.1 3923.2 5280.1 3213.4 3311.0 3056.4 3188.0 2135.4 2929.6 True False 2764.4613692897233 3578.1474434424003 3871.1758046266596 4062.8545217317983 2767.27487732154 3103.9626465872625 3328.413678968646 2695.3678529520794 2248.272884494498 2827.0355957008414 0.9778657804994473 1.2656888540362907 1.369341019445837 1.437143037006787 0.9788609954292116 1.0979566905020766 1.1773511745059968 0.9534255094102836 0.7952757609113641 1.0 11.46507433317174 -7.377695764768239 0.9188216131639955 0.8979119300327738 1.240497749448243 0.3941196253073348 0.15039173276878093 0.6134547034813521 0.9817015741997088 0.12705325675588983 0.06723161338814963 4.190870443141734e-08 7.377695764768239 0.3425858194154692 S(ph)PQVKPASTMGMGPLGK ddPTM_PC-9_AZD4547_30min_R2 2 SPQVKPASTMGMGPLGK 17 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 S(0.999)PQVKPASTMGMGPLGK;S(0.994)PQVKPAS(0.003)T(0.003)MGMGPLGK 72.523 0.0056153999999999996 88341000.0 193507.0 208294.0 218299.0 185308.0 216805.0 271342.0 203358.0 265792.0 240248.0 221482.0 True False 255038.20080436036 275620.9620888249 215404.21262596746 142588.10358006044 186705.3680767085 254374.94184544886 221456.4680433536 224719.95369254667 252947.01880398733 213727.9825938738 1.1932840880690119 1.2895876278987772 1.007842819698901 0.6671475669660277 0.8735653881667254 1.1901808025241714 1.0361603817884975 1.051429723732338 1.1834997726275158 1.0 17.705416281388814 -5.2716452797497135 21.626200642166392 0.9945700373031444 1.2414358386098434 0.30904638614106117 0.14339150635620282 127.83044256032599 270876.4831921074 0.04137846481697451 0.08823701886394515 5.350011557896983e-06 5.2716452797497135 0.246865801306699 S(ph)PQVKPASTMGMGPLGK ddPTM_PC-9_Lapatinib_30min_R1 2 SPQVKPASTMGMGPLGK 17 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 S(0.998)PQVKPAS(0.001)TMGMGPLGK;S(1)PQVKPASTMGMGPLGK 78.069 0.0034311999999999997 43838000.0 92052.0 98262.0 89248.0 86102.0 104311.0 94245.0 92119.0 89326.0 98473.0 80789.0 True False 90739.32159973067 98034.48037619937 81910.37394724262 92434.22830785201 98175.63206331652 90214.36104582544 96888.47107827135 93476.41206059526 87381.93377333911 94753.27100542393 0.957637880327493 1.0346289825771569 0.8644595915063856 0.97552546025098 1.0361186587183537 0.9520975908120505 1.0225343151765727 0.9865243813614036 0.9222049312507338 1.0 16.53188812739095 S(ph)PQVLGSSLSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPQVLGSSLSVR 12 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 S(1)PQVLGSSLSVR 84.68700000000001 0.010074 2411100.0 1766.6 3103.6 3658.1 2451.4 6409.7 6011.3 2943.0 2552.1 2313.3 3688.2 True False 2065.6504880595385 3411.7048970221585 3745.3229774215033 2314.0560055460314 5153.765297416446 5696.056845711147 2664.2177345251444 2485.1100791734666 2347.1276361663654 4356.841464224864 0.47411651422736434 0.7830684051821801 0.8596417859532658 0.5311315604543648 1.1829132043787516 1.3073821695103947 0.6115021068362748 0.5703925882039407 0.5387222958281198 1.0 12.089066902404994 -11.966989720388236 2.1131187177784336 2.9345388526202587 0.7771366053059584 0.06262154335357917 0.27055799260921404 11509604.425590752 875478.0564746985 106754743.53956935 0.07886026362206254 1.0789722608565988e-12 11.966989720388236 -2.1574022473143004 S(ph)PQVLGSSLSVR ddPTM_PC-9_Lapatinib_30min_R1 1 SPQVLGSSLSVR 12 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 S(1)PQVLGSSLSVR 103.43 0.0020969 4520300.0 1855.5 2415.4 3382.0 3210.1 2938.4 3166.4 2219.1 2921.8 1847.1 2449.5 True False 1829.0402297429744 2409.807289701733 3103.9450148975325 3446.181462579681 2765.5690891166737 3030.980453238913 2333.9941398603105 3057.5574945553076 1639.0601471747073 2872.8928112464137 0.636654532526551 0.8388086322845546 1.080424930142408 1.1995510062502277 0.96264262916124 1.0550273373839911 0.8124194995105647 1.0642783060286807 0.5705260359030228 1.0 11.488288451020845 -8.235158347485791 24.996256953750713 0.7852627525295535 0.9632764844894941 0.12474687203303081 0.18036778198621792 1335.809309357194 1270510.9131022608 0.12326675679144519 0.04655754947308137 5.818910166422209e-09 8.235158347485791 0.17801373195994064 S(ph)PQVPAAQQMLNFPEK ddPTM_PC-9_AZD4547_30min_R2 1 SPQVPAAQQMLNFPEK 16 0 Q92922 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 1 S(1)PQVPAAQQMLNFPEK 73.168 0.015 7881000.0 19316.0 24041.0 27779.0 24174.0 23536.0 28845.0 28929.0 33521.0 28051.0 22219.0 True False 25458.08620224089 31811.783102621495 27410.632309523833 18601.057784576915 20268.432660932252 27041.317590096507 31503.624957101132 28341.099685949368 29533.718592748504 21441.11957293724 1.1873487350153964 1.483681064060386 1.2784142272179317 0.8675413483564066 0.9453066381158033 1.2611896266941105 1.4693087667336495 1.3218106260515057 1.3774336033285155 1.0 14.388092619307537 -6.991488428640188 24.977659982698658 1.3255691664905476 1.1561504415342414 0.0968369428752941 0.1950150750289688 420.7514645802925 1234711.4496701409 0.07445264073344518 0.06556016747970089 1.019791931060367e-07 6.991488428640188 -0.16941872495630617 S(ph)PQVPAAQQMLNFPEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPQVPAAQQMLNFPEK 16 0 Q92922 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 1 S(1)PQVPAAQQMLNFPEK;S(1)PQVPAAQQMLNFPEK;S(1)PQVPAAQQMLNFPEK;S(1)PQVPAAQQMLNFPEK 86.179 0.0064459 18102200.0 104301.0 128814.0 136895.0 120025.0 123542.0 109615.0 125203.0 93882.0 104561.0 90986.0 True False 121957.09926134818 141601.80261793185 140159.09597717892 113300.38837630014 99334.83195366753 103866.5964338209 113342.86544877732 91417.69697620152 106090.00681502267 107481.04155522006 1.134684754601032 1.3174584147026684 1.3040355205822043 1.0541430073329752 0.924207939524225 0.9663713240112008 1.0545382125883629 0.8505471816556063 0.9870578595064813 1.0 16.7137226815413 -5.9067086739389465 4.067275564967682 0.9625872291756205 1.25748167240786 0.7813708490487428 0.06799556793618373 0.09396800344898333 2.9065389137493574 0.019484024827569894 0.02981436428072604 1.2396278538303704e-06 5.9067086739389465 0.29489444323223946 S(ph)PQVPAAQQMLNFPEK ddPTM_PC-9_Lapatinib_30min_R1 2 SPQVPAAQQMLNFPEK 16 0 Q92922 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 1 S(1)PQVPAAQQMLNFPEK;S(1)PQVPAAQQMLNFPEK 102.03 0.0013718 7756300.0 32148.0 41113.0 38873.8 33745.0 39732.0 38482.0 42542.0 37314.6 38395.0 38852.0 True False 31689.563624778824 41017.80537447519 35677.74622120746 36226.719870020046 37395.0418761175 36836.21456592341 44744.616600395326 39048.3725396446 34070.550782725804 45567.51643296415 0.6954419750174089 0.9001545088553995 0.7829644671044153 0.7950119450401548 0.8206513060928076 0.8083875850489758 0.9819410866120075 0.8569344040746643 0.7476938277478452 1.0 15.475718121023757 -7.052025436635778 24.99552325894064 0.8862122688491915 0.804492012367132 0.25312603246150245 0.0800086618677981 569.7581201622755 273737.4313488496 0.029682227208057615 0.022991982304564534 8.871040528156908e-08 7.052025436635778 -0.0817202564820595 S(ph)PRPASPASNVVVLPSGSTVYVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPRPASPASNVVVLPSGSTVYVK 23 1 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;Q7Z589-2 E9PMC9 C11orf30;EMSY Protein EMSY 1 S(0.609)PRPAS(0.365)PAS(0.026)NVVVLPSGSTVYVK 67.979 0.00065284 9198700.0 36329.0 23700.0 33314.0 35750.0 44501.0 30034.0 34518.0 29547.0 34050.0 30730.0 True False 42478.782169543185 26052.77937215658 34108.33210404854 33747.0434030638 35781.34850310141 28458.964168164737 31248.205151321406 28771.42255763429 34547.916833728756 36301.105741453866 1.1701787397906933 0.7176855591593106 0.9395948527567495 0.9296422991470072 0.9856820549199161 0.783969622602051 0.8608058766550925 0.7925770295415246 0.9517042560573281 1.0 15.147725873319123 -6.746628047924396 24.997952818838975 0.8637845558168696 0.9341818314287077 0.0683745939353052 0.1195833225665406 666.7229113496537 1125264.9023741218 0.03763805433837714 0.0374869864243203 1.792140077655125e-07 6.746628047924396 0.07039727561183806 S(ph)PRPPPR ddPTM_PC-9_AZD4547_30min_R2 1 SPRPPPR 7 1 Q9HB15 Q9HB15 KCNK12 Potassium channel subfamily K member 12 1 S(1)PRPPPR 60.799 0.039695 0.0 829.51 0.0 676.67 1742.8 1347.8 898.6 0.0 1153.4 717.89 932.1 True False 1093.2769251201516 0.0 667.696913671676 1341.024385991588 1160.6812347214698 842.4103999466367 0.0 975.1685324952723 755.8361997985181 899.4674627091596 1.215471343262652 0.0 0.7423246991732196 1.4909092786441398 1.2904093620302228 0.9365657290251842 0.0 1.084162099158211 0.840315221099794 1.0 9.8129272842174 -5.52333464632264 24.99999836361161 0.9412098479611877 0.5485923008552116 0.08295783941333834 0.4571389104034294 34.03191842754158 1866169.6354656646 0.12812739600986173 0.22461137251655747 2.996852399555659e-06 5.52333464632264 -0.3926175471059761 S(ph)PRPSPVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPRPSPVPK 9 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.999)PRPS(0.001)PVPK 54.471000000000004 0.044805000000000005 5766100.0 28299.0 48257.0 45468.0 38654.0 41886.0 26256.0 39739.0 27746.0 28578.0 21813.0 True False 33089.46176927258 53047.6360405975 46552.12955835026 36488.34169795885 33678.73898116687 24879.08913895364 35974.63423455476 27017.69689931704 28995.89918573571 25767.524228387007 1.2841537074337666 2.0587013160603584 1.8066201915923967 1.416059275798067 1.3070226958034412 0.9655211311122155 1.3961230390509543 1.048517376362948 1.1252885193289985 1.0 14.653266307704943 -6.091602409319292 2.0869577190140474 1.1353648616446863 1.746933339450454 0.5885967563920691 0.21602175395028167 0.2140107646571467 1.8437064789170292 0.0683263946616471 0.1001956502094228 8.098369546110711e-07 6.091602409319292 0.6115684778057677 S(ph)PRPSPVPK ddPTM_PC-9_Lapatinib_30min_R1 1 SPRPSPVPK 9 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.997)PRPS(0.003)PVPK 62.633 0.028712 4991600.0 8270.8 25271.0 23538.0 20563.0 24932.0 21386.0 22848.0 23338.0 23394.0 21881.0 True False 8152.85687532104 25212.486552145623 21602.796499307547 22075.27161615713 23465.54877819796 20471.370633200928 24030.957643877387 24422.368679557745 20759.12137025882 25663.101695400204 0.3176878996190215 0.9824411270078336 0.8417843156963206 0.8601949942829339 0.9143691614799575 0.7976966648918423 0.936401138455709 0.9516530374789091 0.8089092899468048 1.0 14.64740792761323 -4.756008112839309 24.999993790855523 0.8932015292240125 0.3176869925054942 0.8709414973998816 0.06712680271111424 54.47415349792414 250716.6956653869 0.015743514311226177 0.13256613178277915 1.753847738778056e-05 4.756008112839309 -0.5755145367185184 S(ph)PRPTGSDLLPGAPILSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPRPTGSDLLPGAPILSLR 19 1 Q8N1F8 Q8N1F8 STK11IP Serine/threonine-protein kinase 11-interacting protein 1 S(0.999)PRPT(0.001)GSDLLPGAPILSLR 88.781 0.00051702 7597100.0 8661.3 14032.0 11764.0 13401.0 16296.0 12401.0 16121.0 12152.0 14321.0 12269.0 True False 10127.48702152728 15425.004225742656 12044.498375218447 12650.185416628201 13102.915781814816 11750.669729287176 14593.902174067236 11833.0228761083 14530.4175323298 14493.272578649445 0.6987715829236829 1.0642871816587358 0.8310406300480145 0.872831539459462 0.9040688161152222 0.8107671794289928 1.0069431934624642 0.8164493430931498 1.0025629100314497 1.0 13.823095771539545 -8.284768979618006 23.481470301246105 1.0012816015737562 0.8835139014347281 0.20652778720554443 0.0975328578644303 656.8571832313614 661120.0951984503 0.08526391080770757 0.022089777268339716 5.190760849564145e-09 8.284768979618006 -0.11776770013902815 S(ph)PRPTSAPAITQGQVAEGGVLDASAK ddPTM_PC-9_AZD4547_30min_R2 1 SPRPTSAPAITQGQVAEGGVLDASAK 26 1 A0A2R8Y5C8;Q4VB86;A0A2U3TZH6;A0A3B3IU06;A0A2R8Y5Z6;A0A2R8Y5G2;A0A2R8Y570;A0A2R8YCW8;A0A2R8Y6G5;A0A2R8YFR9;A0A2R8Y4N6;A0A2R8YD30;A0A3B3IUD6;A0A2R8Y7Y3;A0A2R8Y7N0;A0A2R8Y420;A0A3B3ITP0;A0A2R8Y6D0;A0A1B0GWG0;P11171-3;P11171-4;P11171-7;P11171-6;P11171-5;P11171-2;P11171 A0A2R8Y5C8 EPB41 Protein 4.1 1 S(0.369)PRPT(0.314)S(0.314)APAIT(0.002)QGQVAEGGVLDASAK 79.877 1.7800999999999998e-05 13282000.0 57533.0 52917.0 100490.0 135660.0 116410.0 112330.0 71738.0 93887.0 64321.0 92527.0 True False 75827.29723925889 70021.38540166467 99157.43694100046 104385.68292610657 100248.48088286565 105305.98734253905 78122.54302507926 79378.92145862967 67720.87674607598 89287.65789302674 0.8492472423244165 0.7842224452292779 1.110539119077336 1.1690941994600015 1.1227585452288467 1.1794013845530975 0.8749534355428594 0.8890245676925642 0.7584573091525217 1.0 16.446173146977586 -7.370840127484634 10.863695317317697 0.870747402410591 1.0377988833432343 0.24269217312429847 0.1339051316910983 0.803209998324118 75.26785240484526 0.06258352680590647 0.04216329948161866 4.2575511329212646e-08 7.370840127484634 0.16705148093264333 S(ph)PRSPQLSDFGLER ddPTM_PC-9_AZD4547_30min_R2 1 SPRSPQLSDFGLER 14 1 Q8IX90;Q8IX90-3 Q8IX90 SKA3 Spindle and kinetochore-associated protein 3 1 S(0.5)PRS(0.5)PQLSDFGLER 68.171 0.015394999999999999 3391700.0 2343.9 1750.5 2587.8 7456.7 6609.9 8040.4 2506.3 2521.3 0.0 3278.7 True False 3089.2114438513386 2316.3148921067727 2553.4840811615163 5737.67301986658 5692.229480179135 7537.632516949632 2729.355844653552 2131.6910187101867 0.0 3163.913710958612 0.9763892843067962 0.7321043188010867 0.8070650196044235 1.8134732941652076 1.7991102160793402 2.3823761346088856 0.8626517958438898 0.6737513135477771 0.0 1.0 11.627494538559498 S(ph)PS(ph)PYYSR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSPYYSR 8 0 Q13595;Q13595-4;Q13595-3;P62995;H7C2L4;P62995-3;H7BXF3 Q13595;P62995 TRA2A;TRA2B Transformer-2 protein homolog alpha;Transformer-2 protein homolog beta 2 S(1)PS(0.999)PY(0.001)YSR 106.4 0.046357999999999996 18409000.0 60877.0 73886.0 95458.0 94952.0 87066.0 77211.0 61485.0 98094.0 107620.0 71374.0 True False 60008.882816525474 73714.9215065423 87609.8117185359 101935.08683058668 81944.9490583421 73908.86551763184 64668.392451584456 102651.80534975285 95498.702311159 83710.90080012298 0.7168586437722017 0.8805892757330597 1.0465759044658038 1.2177038576371038 0.9789041603315504 0.8829061067459361 0.7725205658220494 1.2262656878445877 1.1408156094172468 1.0 16.353127881731083 -4.965964392296749 2.7274921811576776 1.0305450931340572 0.7096910229388987 0.36042244434305093 0.13359355100570947 0.39134298052333255 5.128259002671586 0.038395273925687964 0.23692507259582135 1.08152262145028e-05 4.965964392296749 -0.32085407019515844 S(ph)PSAGDVHILTGFAK ddPTM_PC-9_AZD4547_30min_R2 2 SPSAGDVHILTGFAK 15 0 A0A3B3ITL0;Q9Y2H2;A0A3B3IRJ9;Q9Y2H2-4 A0A3B3ITL0 INPP5F Phosphatidylinositide phosphatase SAC2 1 S(0.991)PS(0.009)AGDVHILTGFAK;S(0.893)PS(0.107)AGDVHILTGFAK 154.65 0.00014214 9877900.0 28465.0 34714.0 37826.0 49790.0 51439.0 51242.0 44786.0 48826.0 42284.0 48152.0 True False 37516.277891219055 45934.621630730915 37324.402524930665 38311.68474783173 44297.58275177151 48037.82963951207 48771.86723802176 41281.06360986143 44519.04591550312 46466.213136328115 0.8073883228045575 0.9885596120338545 0.8032589704571768 0.8245062845002742 0.9533288762268184 1.0338227799750532 1.049620013038916 0.8884103270637984 0.9580949879622821 1.0 15.503894453663094 -6.407660599050296 5.053342007791399 0.9839878740327751 0.8623477203931083 0.4809590502862433 0.06391348275909647 0.22322034716719408 8.399050292459256 0.020910519546633054 0.023671047414799605 3.911464571658498e-07 6.407660599050296 -0.12164015363966685 S(ph)PSAGDVHILTGFAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSAGDVHILTGFAK 15 0 A0A3B3ITL0;Q9Y2H2;A0A3B3IRJ9;Q9Y2H2-4 A0A3B3ITL0 INPP5F Phosphatidylinositide phosphatase SAC2 1 S(0.798)PS(0.202)AGDVHILTGFAK;S(0.954)PS(0.046)AGDVHILTGFAK 83.25200000000001 0.0039457 17235400.0 38129.0 65912.0 63804.0 53338.0 60624.0 40830.0 62131.0 36324.0 39829.0 43535.0 True False 44583.486617922674 72455.30776276738 65325.32933801751 50349.644784129145 48745.16239302538 38688.80292289294 56245.501890513675 35370.53348845933 40411.4237759349 51427.55087712961 0.8669183318575926 1.4088811644147154 1.27023994384046 0.9790402989328465 0.9478414111044685 0.752297207684029 1.0936842398910864 0.687774021612781 0.7857932778577309 1.0 15.650253829729184 -5.9700143099717256 2.9729378686040446 0.86859501930762 1.2031317016018426 0.38316204756053207 0.17031929409070085 0.24427353595280046 4.4199666283478845 0.05038479407678566 0.07635120170360749 1.0714839993357688e-06 5.9700143099717256 0.3345366822942226 S(ph)PSAGDVHILTGFAK ddPTM_PC-9_Lapatinib_30min_R1 2 SPSAGDVHILTGFAK 15 0 A0A3B3ITL0;Q9Y2H2;A0A3B3IRJ9;Q9Y2H2-4 A0A3B3ITL0 INPP5F Phosphatidylinositide phosphatase SAC2 1 S(0.762)PS(0.238)AGDVHILTGFAK;S(0.5)PS(0.5)AGDVHILTGFAK 82.90799999999999 0.0041455 8684400.0 47820.0 92818.0 88585.0 74359.0 111173.0 102345.0 98473.0 108995.0 92676.0 85624.0 True False 47138.078030886005 92603.08562372086 81301.88324798859 79827.60891435221 104634.02271452754 97967.94292784765 103571.4501079104 114059.30560580998 82237.85295845554 100423.99431319161 0.46939059089680113 0.922121115148241 0.8095862328920415 0.7949057340359755 1.041922534849651 0.9755431816654864 1.0313416710443009 1.1357774243682641 0.8189064129632299 1.0 16.615744488156402 -4.304080898826564 0.6549863146611508 1.0017690507217756 1.7061308885826448e-15 0.6090504868168265 0.11191968121160044 4.0429805334366735 0.8398869279954435 0.04889870511274697 3.4817569818119125 4.964998266195653e-05 4.304080898826564 -1.0017690507217738 S(ph)PSAGILR ddPTM_PC-9_AZD4547_30min_R2 3 SPSAGILR 8 0 Q99618;F5GX58;F8WDL1;J3KMY0 Q99618 CDCA3 Cell division cycle-associated protein 3 1 S(0.997)PS(0.003)AGILR;S(0.999)PS(0.001)AGILR;S(0.998)PS(0.002)AGILR 104.2 0.0038619 35128000.0 23588.7 19676.100000000002 37807.0 46507.0 34536.0 34159.8 32344.3 54323.0 30627.2 28751.7 True False 31089.415924559948 26036.01453789321 37305.65447734504 35785.52967598737 29741.27253475343 32023.782305917128 35222.88004078837 45928.628568354994 32246.091265331972 27745.111734336362 1.1205366993020538 0.9384000607815887 1.344584762698104 1.2897958393045672 1.0719463961627045 1.154213492183765 1.2695166045122748 1.6553773150430444 1.162226037295981 1.0 14.759945992531227 -7.368827588995061 4.711350001096648 1.332636080703816 1.1550919667890642 0.057215846664865344 0.18823681821824464 0.4398143145065478 15.513568714142739 0.08069273255916863 0.05324420135588874 4.2773265847034215e-08 7.368827588995061 -0.17754411391475178 S(ph)PSAGILR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPSAGILR 8 0 Q99618;F5GX58;F8WDL1;J3KMY0 Q99618 CDCA3 Cell division cycle-associated protein 3 1 S(0.997)PS(0.003)AGILR;S(0.997)PS(0.003)AGILR;S(0.999)PS(0.001)AGILR 101.9 0.0044453 26990300.0 28806.4 34920.2 30621.0 36557.0 54912.0 38776.9 28273.0 40474.1 34188.7 21588.1 True False 33682.754567665754 38386.84667643805 31351.120770789184 34508.82980939313 44152.38778909025 36743.37110116891 25594.77676120606 39411.69776085377 34688.645058834154 25501.851638694436 1.3207964286231781 1.505257234662638 1.2293664481687887 1.3531891839976136 1.7313404694934782 1.4408118916909354 1.0036438578589575 1.5454445551339364 1.3602402504059912 1.0 14.638314381652364 -12.556944597482579 0.3840366851234664 1.659799245347211e-09 1.4017158774691598 0.28706994437161026 0.18381751838816696 156.8669873057224 4.8936682980373805 127.49269921685664 0.12624376505871876 2.773673916921286e-13 12.556944597482579 1.4017158758093606 S(ph)PSAGILR ddPTM_PC-9_Lapatinib_30min_R1 3 SPSAGILR 8 0 Q99618;F5GX58;F8WDL1;J3KMY0 Q99618 CDCA3 Cell division cycle-associated protein 3 1 S(0.99)PS(0.01)AGILR;S(0.994)PS(0.006)AGILR;S(0.987)PS(0.013)AGILR 94.309 0.006772800000000001 27621000.0 27882.9 32929.8 28091.699999999997 16736.100000000002 24710.2 26323.300000000003 18547.2 24256.100000000002 26384.6 15172.5 True False 27485.28473290239 32853.55307130089 25782.108863097856 17966.928623992964 23256.794618122374 25197.51382160936 19507.48326385341 25383.12695724658 23412.888505844698 17795.046408914557 1.5445469543217059 1.8462190160314877 1.4488362812126256 1.00965899223462 1.306925201750062 1.4159847208370573 1.0962310980027001 1.426415327837005 1.3156969623926265 1.0 14.119188074904795 -5.512523268356249 7.590436041738039 1.2464790871531555 1.685110258230575 0.58170189981932 0.159607628322311 0.09609587901478746 36.03399881873626 0.04114544504317551 0.07863315390320266 3.0723927501337738e-06 5.512523268356249 0.43863117107741956 S(ph)PSAIPEQNHSLNDQAK ddPTM_PC-9_AZD4547_30min_R2 2 SPSAIPEQNHSLNDQAK 17 0 Q13129 Q13129 RLF Zinc finger protein Rlf 1 S(0.998)PS(0.002)AIPEQNHSLNDQAK;S(0.566)PS(0.434)AIPEQNHSLNDQAK 213.36 3.3103e-22 16512400.0 25025.9 22223.8 31109.0 40753.0 32409.0 26779.0 29609.0 32005.0 25889.2 26938.0 True False 32983.615628942876 29407.20873990429 30696.47433374048 31358.025477573538 27909.56977006093 25104.50489669595 32244.143639766608 27059.362651735024 27257.65025815068 25994.90881928906 1.2688490603386142 1.1312680088372995 1.1808648588512343 1.2063141169514269 1.0736552285711858 0.9657469880435818 1.2404022596855742 1.0409485503429081 1.0485764904058685 1.0 14.665941474326672 -1.5228787655021192 0.16729306157190393 0.9940989536310453 1.9578116100116787 0.4332128281192803 0.07507361459020981 63.74574530263269 0.6820592875719204 0.20636303630401942 15.306497972011769 0.029999998603128845 1.5228787655021192 0.9637126563806334 S(ph)PSAIPEQNHSLNDQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPSAIPEQNHSLNDQAK 17 0 Q13129 Q13129 RLF Zinc finger protein Rlf 1 S(0.699)PS(0.3)AIPEQNHSLNDQAK;S(0.772)PS(0.228)AIPEQNHSLNDQAK;S(1)PSAIPEQNHSLNDQAK;S(1)PSAIPEQNHSLNDQAK 226.79 6.876099999999999e-81 21698500.0 95876.0 91141.0 95127.0 119865.0 107929.0 114720.0 110819.0 101896.0 106962.0 101564.0 True False 112105.91316268318 100188.87615011513 97395.18845115657 113149.35265757306 86781.08722480913 108703.88124698206 100321.4220599192 99221.33796773608 108526.1168977766 119976.74921981836 0.9343969885138792 0.835069101318553 0.8117838588267763 0.9430940027410118 0.7233158740266501 0.9060412284368329 0.8361738646219931 0.8270047206058672 0.9045595717795104 1.0 16.872395321642706 -8.58609972443288 3.7401784098716684 0.9999113320271634 0.8505266081944542 0.35444318304930644 0.06116657692445032 0.30336167112901496 11.686733964234534 0.05507021723370383 0.01447120589517993 2.5935837446829157e-09 8.58609972443288 -0.14938472383270918 S(ph)PSAIPEQNHSLNDQAK ddPTM_PC-9_Lapatinib_30min_R1 3 SPSAIPEQNHSLNDQAK 17 0 Q13129 Q13129 RLF Zinc finger protein Rlf 1 S(0.998)PS(0.002)AIPEQNHSLNDQAK;S(0.5)PS(0.5)AIPEQNHSLNDQAK;S(1)PSAIPEQNHSLNDQAK 264.0 3.4254999999999995e-69 69149900.0 188275.0 154824.0 169798.0 133149.0 149902.0 178760.0 156781.0 132501.0 169257.0 114387.0 True False 185590.16397459403 154465.51454035804 155837.8638792347 142941.22163204313 141085.0590786712 171114.85150991287 164898.35304467552 138657.4801786817 150193.4943047745 134158.64053890307 1.3833634809438677 1.1513646375655278 1.161593940228137 1.0654641479509723 1.0516285683273574 1.2754664986359436 1.229129576613879 1.0335337300803527 1.1195215880353355 1.0 17.033580449357196 -4.683914171181706 2.658564008136993 1.1241801394218798 1.4816948496974678 0.4793477135871189 0.0823754367262771 0.697687499129524 4.998477733948741 0.022043952178597562 0.6220365756627929 2.0705505074409822e-05 4.683914171181706 0.357514710275588 S(ph)PSAMQQQDGLDR ddPTM_PC-9_AZD4547_30min_R2 1 SPSAMQQQDGLDR 13 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47;O60343-4;O60343-5 O60343-2 TBC1D4 TBC1 domain family member 4 1 S(0.939)PS(0.061)AMQQQDGLDR 86.49799999999999 0.0066622 4609600.0 6418.0 10497.0 9344.1 5531.3 6995.0 11706.0 10823.0 13773.0 9681.2 4965.2 True False 8458.790497307002 13889.94996997703 9220.191128673518 4256.144242733113 6023.864992489004 10974.021969480667 11786.226033070816 11644.699322054263 10192.928467438482 4791.369859289259 1.76542215393945 2.8989517357020387 1.9243329985886792 0.8882938215428146 1.257232309213251 2.2903725430848976 2.459886499937026 2.4303486610364935 2.127351627359128 1.0 12.22622246811091 S(ph)PSAMQQQDGLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSAMQQQDGLDR 13 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47;O60343-4;O60343-5 O60343-2 TBC1D4 TBC1 domain family member 4 1 S(0.649)PS(0.351)AMQQQDGLDR;S(0.86)PS(0.14)AMQQQDGLDR 84.734 0.0074329999999999995 10451800.0 15345.5 30593.0 25383.0 15291.0 18109.5 14118.599999999999 15938.099999999999 8076.0 13896.4 12942.6 True False 17943.19006255952 33630.070857906576 25988.226985563553 14434.294844090864 14561.07347513349 13378.195761625186 14428.327786148548 7864.013557229308 14099.608560594079 15288.990926434777 1.173601982556979 2.1996265822723418 1.6998000136575213 0.944097286311673 0.9523894379423882 0.8750214991948349 0.9437070016963555 0.5143579190456822 0.9222066144480309 1.0 13.900205571502038 -5.7728846378551255 4.696739009294097 0.8574286685567899 1.7528352837348269 0.6652938151163641 0.2635382740127322 0.09951438023177814 5.530571851519554 0.07168314029336723 0.11658270326936315 1.6870010859237694e-06 5.7728846378551255 0.895406615178037 S(ph)PSAMQQQDGLDR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSAMQQQDGLDR 13 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47;O60343-4;O60343-5 O60343-2 TBC1D4 TBC1 domain family member 4 1 S(0.93)PS(0.07)AMQQQDGLDR 68.262 0.029262 3273700.0 3194.1 7968.3 5091.4 4709.0 7360.9 5520.1 6979.0 7392.2 5851.4 5003.3 True False 3148.5515482738 7949.849890920891 4672.804745372353 5055.315568763502 6927.946334086206 5284.0181909815965 7340.338471490736 7735.668598552865 5192.353714026352 5868.113738521812 0.5365525769558321 1.354753886028711 0.7963043924485078 0.8614890225418407 1.180608734388875 0.9004628107826435 1.2508855142504072 1.318254714078104 0.884842037048572 1.0 12.518681118933637 -6.256956491402657 24.858641733592883 1.1037382241891918 0.9141684188482097 0.1509260144221456 0.2295545946228566 737.6211048127207 4090275.8139700554 0.0663703852394762 0.08278226374114395 5.534055478503575e-07 6.256956491402657 -0.1895698053409821 S(ph)PSAPAATSSASSSTSSYK ddPTM_PC-9_AZD4547_30min_R2 4 SPSAPAATSSASSSTSSYK 19 0 A0A087X0S7;A0A0C4DH00;A0A087WTU1;A0A0B4J2G4;Q15345-3;Q15345 A0A087X0S7 LRRC41 Leucine-rich repeat-containing protein 41 1 S(0.979)PS(0.021)APAATSSASSSTSSYK;S(0.999)PS(0.001)APAATSSASSSTSSYK;S(1)PSAPAATSSASSSTSSYK;S(0.935)PS(0.064)APAATSSASSSTSSYK 213.36 1.2962e-27 22628100.0 92995.0 81547.0 99555.0 149629.0 121073.0 99204.0 95732.0 105834.0 87463.0 115481.0 True False 122565.47558383708 107905.47301150016 98234.8356519186 115134.34579500517 104264.10382210469 93000.75819753614 104251.96254254217 89479.78712337824 92086.11562074648 111438.04533968086 1.099853063738134 0.9683001230198102 0.8815197301108721 1.0331691070500868 0.9356239469589686 0.8345512335042764 0.9355149960210234 0.8029554614909983 0.8263436005185965 1.0 16.76588233236047 -6.545915131639981 5.517347176664476 0.8716985456527938 0.9857589996873476 0.3450481432788731 0.07427723538512747 0.20243674034853962 18.387675948436666 0.024290959831252568 0.02490626101881299 2.845017016740285e-07 6.545915131639981 0.11406045403455378 S(ph)PSAPAATSSASSSTSSYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPSAPAATSSASSSTSSYK 19 0 A0A087X0S7;A0A0C4DH00;A0A087WTU1;A0A0B4J2G4;Q15345-3;Q15345 A0A087X0S7 LRRC41 Leucine-rich repeat-containing protein 41 1 S(0.998)PS(0.002)APAATSSASSSTSSYK;S(0.998)PS(0.002)APAATSSASSSTSSYK;S(0.936)PS(0.064)APAATSSASSSTSSYK;S(0.97)PS(0.03)APAATSSASSSTSSYK 243.37 1.4414999999999999e-53 19550500.0 71139.0 78283.0 74416.0 92258.0 92667.0 80417.0 90799.0 109122.0 81202.0 67927.0 True False 83181.42764070405 86054.41888567651 76190.35966425172 87089.08336447172 74509.56656562568 76199.7909539623 82197.86139216743 106257.66312431618 82389.42563090865 80241.62739016405 1.0366368473092602 1.0724410967794626 0.949511645542611 1.085335457380654 0.9285649978574462 0.9496291816646631 1.024379291218652 1.3242211876842014 1.0267666336115195 1.0 16.29206324526912 -7.552379937804659 24.98798560738067 1.1401564678620852 1.003175712435157 0.21213081438718673 0.09505908559875743 248.44411955265633 210433.31602568735 0.042269979059419524 0.024405062753220477 2.8029804080890744e-08 7.552379937804659 -0.13698075542692822 S(ph)PSAPAATSSASSSTSSYK ddPTM_PC-9_Lapatinib_30min_R1 4 SPSAPAATSSASSSTSSYK 19 0 A0A087X0S7;A0A0C4DH00;A0A087WTU1;A0A0B4J2G4;Q15345-3;Q15345 A0A087X0S7 LRRC41 Leucine-rich repeat-containing protein 41 1 S(0.999)PS(0.001)APAATSSASSSTSSYK;S(0.944)PS(0.05)APAAT(0.001)S(0.001)S(0.001)AS(0.002)S(0.001)STSSYK;S(1)PSAPAATSSASSSTSSYK;S(1)PSAPAATSSASSSTSSYK 218.64 5.735399999999999e-28 32481900.0 37917.5 46929.7 53793.0 54734.6 52912.4 61010.4 47296.5 49016.0 52301.0 42136.5 True False 37376.78949678213 46821.03716300216 49370.34718698492 58759.965073273015 49800.19666178092 58401.127414188806 49745.28134644814 51293.46230170549 46410.310626053986 49419.73788164301 0.7563129854370547 0.9474157324576556 0.9990005876846946 1.1889979103895538 1.0076985187790573 1.1817368913217556 1.00658731670299 1.037914495308533 0.9391047507618029 1.0 15.59279973829675 -4.793870055389862 1.7645717451752414 1.0548077269541822 0.6622846229390976 0.5757814692649119 0.07588007157536637 0.6135669158109921 1.9842135874079738 0.020779835922454165 0.40638518166709936 1.6074221354689616e-05 4.793870055389862 -0.3925231040150846 S(ph)PSAPAATSSASSSTSSYKR ddPTM_PC-9_AZD4547_30min_R2 2 SPSAPAATSSASSSTSSYKR 20 1 A0A087X0S7;A0A0C4DH00;A0A087WTU1;A0A0B4J2G4;Q15345-3;Q15345 A0A087X0S7 LRRC41 Leucine-rich repeat-containing protein 41 1 S(0.746)PS(0.254)APAATSSASSSTSSYKR;S(0.978)PS(0.022)APAATSSASSSTSSYKR 105.9 6.265100000000001e-05 25122000.0 19094.3 17982.8 31339.0 30034.0 30602.0 28608.0 20860.4 26974.0 21211.8 27710.3 True False 25165.89021388736 23795.388427179463 30923.424383461144 23110.125320674397 26353.440528970463 26819.137237562187 22716.935188050487 22805.78810085613 22333.01244325204 26740.170831358886 0.9411267554197774 0.8898742112475212 1.1564407938335401 0.8642474824271713 0.9855374782447203 1.0029531002887497 0.8495433829244559 0.8528662080988352 0.8351858551726805 1.0 14.706721061763327 -7.263812689209336 24.865449101999964 0.8721377090710619 0.9734836113908988 0.20114144114443766 0.08547117025913942 286.82170700975206 3005039.748301415 0.03354611313406308 0.023844046730289944 5.447375469619493e-08 7.263812689209336 0.10134590231983687 S(ph)PSAPAATSSASSSTSSYKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSAPAATSSASSSTSSYKR 20 1 A0A087X0S7;A0A0C4DH00;A0A087WTU1;A0A0B4J2G4;Q15345-3;Q15345 A0A087X0S7 LRRC41 Leucine-rich repeat-containing protein 41 1 S(0.853)PS(0.147)APAATSSASSSTSSYKR;S(0.804)PS(0.196)APAATSSASSSTSSYKR 109.67 3.7274e-05 18076600.0 21269.4 15118.3 22278.0 26795.0 24941.0 25127.0 31390.0 23955.0 22843.3 20913.6 True False 24869.889330201284 16619.144910636063 22809.192009785478 25293.76302056209 20053.99009046656 23809.29588644453 28416.511956080278 23326.206632420515 23177.3400472222 24705.070128033498 1.0066714727508812 0.6727017905437103 0.9232595532648694 1.0238288290410715 0.8117358091491821 0.9637412791404099 1.1502299652991193 0.9441870236163245 0.938161273257114 1.0 14.59251953058776 -6.990742882386052 23.521700640510975 1.0111352119789312 0.8854929268173924 0.2208606376326374 0.10735276382115562 148.9207350118424 378392.9655649897 0.038120996707220245 0.033560387535250875 1.021544094761662e-07 6.990742882386052 -0.12564228516153875 S(ph)PSAPAATSSASSSTSSYKR ddPTM_PC-9_Lapatinib_30min_R1 2 SPSAPAATSSASSSTSSYKR 20 1 A0A087X0S7;A0A0C4DH00;A0A087WTU1;A0A0B4J2G4;Q15345-3;Q15345 A0A087X0S7 LRRC41 Leucine-rich repeat-containing protein 41 1 S(0.78)PS(0.22)APAATSSASSSTSSYKR;S(0.799)PS(0.201)APAATSSASSSTSSYKR 141.85 3.3956e-05 24467000.0 52496.0 32066.0 35562.0 32732.0 30217.0 34847.0 24186.0 20812.0 35961.0 17297.7 True False 51747.39741341267 31991.753147129162 32638.229633289786 35139.22047075111 28439.69546890775 33356.675042324554 25438.23273699312 21779.00149794137 31910.693493882107 20287.584397263563 2.550692896705459 1.5769128803449013 1.6087785018748761 1.732055417868811 1.4018275863706948 1.6441915601752854 1.2538817948392262 1.0735137841683593 1.5729173502877107 1.0 14.308309476011438 -1.5228787452803376 0.5174879669519884 1.3145208367031687 39.478970226696916 0.6936587496106903 0.2273022469493585 69.50748058745754 0.7028407297251908 0.11971506908357883 2908.1072371319424 0.029999999999999995 1.5228787452803376 38.16444938999375 S(ph)PSAPVCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSAPVCK 8 0 Q6P1L5;Q6P1L5-2 Q6P1L5 FAM117B Protein FAM117B 1 S(0.998)PS(0.002)APVCK;S(0.999)PS(0.001)APVCK 111.46 0.0037457000000000002 23523000.0 80702.0 110944.0 97947.0 115562.0 126487.0 93641.0 109818.0 102890.0 99581.0 86627.0 True False 94363.25466284431 121957.78711664709 100282.42794606592 109087.43579705925 101702.78034452678 88730.30111444066 99415.24402653148 100189.24652096632 101037.18373625677 102331.78936104552 0.9221304078824739 1.1917878879881345 0.9799733647991918 1.0660170849957344 0.9938532393457963 0.8670844286850464 0.9714991269797508 0.9790627833886505 0.9873489398272794 1.0 16.64289486223 -6.5173344426515945 24.899455517742254 0.9570269691936452 1.0444598723958105 0.20595611904268618 0.07269391272641015 334.6716360592355 1503018.3366086094 0.022568308195934347 0.023232541612479132 3.0385441942672445e-07 6.5173344426515945 0.08743290320216535 S(ph)PSAPVCK ddPTM_PC-9_Lapatinib_30min_R1 1 SPSAPVCK 8 0 Q6P1L5;Q6P1L5-2 Q6P1L5 FAM117B Protein FAM117B 1 S(0.999)PS(0.001)APVCK 87.476 0.011696999999999999 15511000.0 112240.0 107190.0 94510.0 103710.0 100160.0 98673.0 80313.0 88253.0 90320.0 76938.0 True False 110639.43701770507 106941.80814073412 86739.75261915 111337.17936641822 94268.78572213645 94452.98580799752 84471.21416547298 92353.55656341607 80147.21048823542 90236.63078655898 1.2261033690343097 1.1851263418033493 0.9612476869212868 1.2338357316306432 1.0446842363287578 1.0467255368987756 0.9361078026647159 1.0234597165076382 0.8881893061567364 1.0 16.46142558161388 -5.968682886018267 0.44285512121411924 0.9439088198099376 1.2447277685852798 0.5121217800477442 0.08059375686889013 1.6488921633273452 0.5208008533890122 0.06999065787999385 0.23646912096073397 1.0747739063768808e-06 5.968682886018267 0.3008189487753422 S(ph)PSASITDEDSNV ddPTM_PC-9_AZD4547_30min_R2 1 SPSASITDEDSNV 13 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;H0YFE4 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.831)PS(0.162)AS(0.007)ITDEDSNV 103.43 0.0044101999999999995 0.0 23325.0 21721.0 34403.0 38652.0 36750.0 35306.0 34060.0 39253.0 36353.0 35086.0 True False 30741.86480986068 28741.888472694194 33946.793741479116 29741.378567447104 31647.89685117527 33098.31023872241 37091.274017037045 33187.35079420576 38274.54536387958 33857.64981934723 0.9079739726144223 0.8489038260496822 1.0026329034238208 0.8784241885109234 0.9347340119600018 0.9775725844919423 1.0955064576231168 0.9802024349381026 1.1304548770543552 1.0 15.047194213632181 -6.940155133196724 2.646844711153719 1.049965495277826 0.9124856054256248 0.5796275399154102 0.054803663906540824 0.1957449016808931 2.7814818332363718 0.02075650410780058 0.017287693803114634 1.1477435657846113e-07 6.940155133196724 -0.13747988985220105 S(ph)PSASITDEDSNV ddPTM_PC-9_Lapatinib_30min_R1 2 SPSASITDEDSNV 13 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;H0YFE4 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.846)PS(0.154)ASITDEDSNV;S(0.885)PS(0.114)AS(0.001)ITDEDSNV 173.72 0.00018923 14583600.0 50108.0 39074.0 45012.0 39244.0 47135.0 48356.0 42531.0 49979.0 51231.0 45778.0 True False 49393.450731318175 38983.52655369938 41311.28711134467 42130.13467414628 44362.6119709755 46287.9266033416 44733.04707421874 52301.20679730983 45460.825293653514 53690.666304649225 0.9199634523261832 0.7260764158243216 0.7694314478598193 0.7846826566668649 0.8262630178447612 0.8621224095208034 0.8331624498827496 0.9741210232062425 0.8467174729347126 1.0 15.712383688497972 -7.873444615248732 0.5340221273065988 0.9875701380306309 0.7884604169571243 0.47300964541384216 0.06062338648351248 0.6710343720380494 0.44077666206677946 0.05907062678425388 0.03573805108239937 1.3383058758808836e-08 7.873444615248732 -0.19910972107350655 S(ph)PSASSLSSMSSVASSVSSR ddPTM_PC-9_AZD4547_30min_R2 1 SPSASSLSSMSSVASSVSSR 20 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0;F5H0N7 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 S(0.869)PS(0.129)AS(0.003)SLSSMSSVASSVSSR 105.92 0.00012006 3050800.0 3152.1 3209.8 5574.4 4462.7 4502.4 4678.1 5338.1 6600.8 6979.8 6804.4 True False 4154.402232247024 4247.305078939912 5500.479813751746 3433.893463027691 3877.3194770811274 4385.577667472023 5813.180558730047 5580.7980312942545 7348.737978455887 6566.180027098172 0.6326969737506575 0.6468456639037579 0.8376985996502755 0.5229666943117991 0.5904985030991684 0.6679039638531149 0.8853215316575926 0.8499307067827391 1.1191800937726581 1.0 12.680838589955444 -7.622273500267747 1.4084012582114152 1.0361845597704398 0.64688749224256 0.7488929736549345 0.09192326874260708 0.22306608583264462 0.8357630784815017 0.07069282003323936 0.030540683041990903 2.3863080139134624e-08 7.622273500267747 -0.38929706752787974 S(ph)PSASSLSSMSSVASSVSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSASSLSSMSSVASSVSSR 20 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0;F5H0N7 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 S(0.686)PS(0.306)AS(0.005)S(0.004)LSSMSSVASSVSSR 100.07 0.00029123 2081500.0 3293.1 3762.5 2716.5 2873.1 3807.2 2629.2 4120.9 4379.4 2624.1 3098.3 True False 3850.5567883102417 4136.016134503761 2781.2716623836195 2712.1295217158777 3061.206490213878 2491.320123557925 3730.538519267639 4264.445390357857 2662.4724981905338 3659.997263870696 1.0520654827588631 1.1300598979491157 0.7599108583601059 0.7410195489730002 0.83639584117515 0.6806890672161827 1.0192735814568181 1.1651498847974318 0.7274520460637689 1.0 11.837626854646363 -9.888197978834945 18.42582357889698 0.9999999965270331 0.9020160976579693 0.029570566749022142 0.1695245022290246 0.0 0.0 0.1736591165535415 0.04211852237657059 1.2936059997572314e-10 9.888197978834945 -0.09798389886906378 S(ph)PSDSGYSYETIGK ddPTM_PC-9_AZD4547_30min_R2 4 SPSDSGYSYETIGK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(1)PSDSGYSYETIGK;S(0.999)PS(0.001)DSGYSYETIGK;S(0.972)PS(0.026)DS(0.001)GYSYETIGK;S(0.756)PS(0.242)DS(0.001)GYSYETIGK 219.84 9.4908e-16 260548000.0 209114.0 253048.0 233983.0 269446.0 254507.0 309239.0 263242.0 338759.0 277666.0 237129.0 True False 275607.9021585948 334840.8173766549 230880.23253822382 207329.38759920184 219173.0961606008 289902.23644457763 286670.02803267393 286411.58045740117 292342.85789362586 228827.18588645052 1.2044368814436148 1.4632912434749377 1.0089720399428068 0.9060522542198444 0.9578105648223096 1.2669046963171327 1.252779589637249 1.2516501452739335 1.2775704808024573 1.0 17.80389893657778 S(ph)PSDSGYSYETIGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SPSDSGYSYETIGK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.985)PS(0.008)DS(0.008)GYSYETIGK;S(0.908)PS(0.092)DSGYSYETIGK;S(0.997)PS(0.003)DSGYSYETIGK;S(0.999)PS(0.001)DSGYSYETIGK;S(0.999)PS(0.001)DSGYSYETIGK 238.88 3.967800000000001e-27 193216000.0 174004.0 273971.0 233201.0 169707.0 206687.0 150090.0 211364.0 128507.0 142224.0 134689.0 True False 203459.44046434524 301169.0302687385 238761.39625971785 160198.86698751742 166188.1660650444 142219.0161816558 191342.071777157 125133.82741442141 144303.75693862702 159107.04950246256 1.278758176338354 1.8928704366683464 1.500633674034804 1.0068621565698632 1.044505360288717 0.893857416289117 1.2025995854708846 0.7864756954875508 0.9069601717200694 1.0 17.279638232525222 -5.729767220445931 4.102615207292664 0.973233585257517 1.6095804254026176 0.7064533193427462 0.17176602473750155 0.10274490202058051 3.7598493125525843 0.04610292767809365 0.07939442322336696 1.8630854730846981e-06 5.729767220445931 0.6363468401451006 S(ph)PSDSGYSYETIGK ddPTM_PC-9_Lapatinib_30min_R1 3 SPSDSGYSYETIGK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.999)PSDS(0.001)GYSYETIGK;S(0.974)PS(0.026)DS(0.001)GYSYETIGK;S(0.906)PS(0.074)DS(0.02)GYSYETIGK 196.18 1.169e-07 244139000.0 145042.0 157377.0 172522.0 148643.0 181423.0 165413.0 162577.0 144033.0 158944.0 142071.0 True False 142973.6744825551 157012.60322571374 158337.90711417832 159574.70207851232 170752.05583134165 158338.67158653607 170994.44156462947 150725.29899831765 141042.05296547906 166627.78305229227 0.8580422295943655 0.9422954584736867 0.9502491374111821 0.9576716388792947 1.024751411220271 0.9502537253156945 1.026206064993176 0.9045628300234662 0.8464497959575942 1.0 17.34626944614842 -4.626872719911745 2.089136735672118 0.9588731521163377 0.796056592819611 0.250237731882625 0.05130029235285381 1.8535273098155696 6.236868901874359 0.014152768766613989 0.6636066589610448 2.3611701275527182e-05 4.626872719911745 -0.16281655929672667 S(ph)PSDSSTAS(ph)TPVAEQIER ddPTM_PC-9_Lapatinib_30min_R1 1 SPSDSSTASTPVAEQIER 18 0 Q16643-3;Q16643;Q16643-2;D6R9Q9 Q16643-3 DBN1 Drebrin 2 S(0.996)PS(0.003)DS(0.003)S(0.002)T(0.008)AS(0.587)T(0.399)PVAEQIER 185.28 5.191199999999999e-42 0.0 18289.0 14391.0 14521.0 12321.0 19419.0 18151.0 13793.0 14102.0 18792.0 12430.0 True False 18028.19550620816 14357.678523680406 13327.139432680975 13227.127441651119 18276.812599222925 17374.724042047605 14507.134050332672 14757.230401882045 16675.447071467213 14578.508938066107 1.2366282164244204 0.9848523319275069 0.9141634092552725 0.9073031746829485 1.2536818872813622 1.1918039160150506 0.995104102344303 1.0122592416395395 1.1438376271750101 1.0 13.831555550677841 -4.749585529392743 24.565091439982783 1.0463541530311804 1.2366287525682522 0.21597132789520612 0.10962355891248132 775.0073583492643 1605945.264369296 0.029702312788431315 0.4674565633561365 1.779977327903955e-05 4.749585529392743 0.19027459953707182 S(ph)PSDSSTASTPVAEQIER ddPTM_PC-9_AZD4547_30min_R2 3 SPSDSSTASTPVAEQIER 18 0 Q16643-3;Q16643;Q16643-2;D6R9Q9 Q16643-3 DBN1 Drebrin 1 S(1)PSDSSTASTPVAEQIER;S(0.9)PS(0.08)DS(0.019)S(0.001)TASTPVAEQIER;S(0.999)PS(0.001)DSSTASTPVAEQIER 197.67 5.506799999999999e-54 191123000.0 18255.7 26608.9 29882.1 24421.6 22458.199999999997 30311.5 21720.45 40521.1 24203.4 27567.9 True False 24060.63285785096 35209.706559600054 29485.84382938272 18791.57742995878 19340.266586750036 28416.117113267817 23653.52797191286 34259.4950772448 25482.742311779573 26602.7562120157 0.9044413543504738 1.3235360381078423 1.1083755229867802 0.7063770866520651 0.7270023614325568 1.0681643994629801 0.8891382450525649 1.2878175029762806 0.9578985766997237 1.0 14.699288105253771 -10.21029178697226 15.484960238598221 0.9999999999838175 1.0008430711716139 0.0 0.19695047702284607 0.0 0.0 0.20180825836018562 0.0489456920788814 6.161808728068869e-11 10.21029178697226 0.0008430711877963626 S(ph)PSDSSTASTPVAEQIER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPSDSSTASTPVAEQIER 18 0 Q16643-3;Q16643;Q16643-2;D6R9Q9 Q16643-3 DBN1 Drebrin 1 S(0.965)PS(0.035)DSSTASTPVAEQIER;S(0.988)PS(0.012)DSSTASTPVAEQIER;S(0.989)PS(0.011)DSSTASTPVAEQIER;S(0.796)PS(0.196)DS(0.007)STASTPVAEQIER 306.07 7.122499999999999e-138 173416000.0 29581.4 60561.8 54202.1 33008.4 34775.0 28511.5 43088.0 13028.2 22066.199999999997 34254.5 True False 34588.94676071801 66573.9752650074 55494.48362660895 31159.0463626767 27961.088384426257 27016.30674837282 39006.392709894484 12686.223554518941 22388.876429850978 40464.56969152721 0.8547958627609109 1.6452411522603483 1.3714339247805918 0.7700328114251769 0.6910017478891162 0.6676533805827102 0.9639641050739246 0.3135143571581161 0.5532957992764455 1.0 15.304371633183491 -5.808288906832657 5.126329871841252 0.6820941520396269 1.3278314081968452 0.5161112184197778 0.25743966792246575 0.13795229343824358 8.011991238432323 0.07192483941722605 0.11167282612040177 1.5549308968029383e-06 5.808288906832657 0.6457372561572183 S(ph)PSDSSTASTPVAEQIER ddPTM_PC-9_Lapatinib_30min_R1 3 SPSDSSTASTPVAEQIER 18 0 Q16643-3;Q16643;Q16643-2;D6R9Q9 Q16643-3 DBN1 Drebrin 1 S(0.997)PS(0.003)DSSTASTPVAEQIER;S(0.931)PS(0.069)DSSTASTPVAEQIER;S(0.873)PS(0.127)DSSTASTPVAEQIER 164.97 1.4926999999999999e-07 215055200.0 10413.699999999999 16100.4 15069.099999999999 14097.699999999999 12964.2 15647.0 16890.5 17723.3 16647.8 13720.0 True False 10265.198728361307 16063.120513005617 13830.17676640816 15134.491886548565 12201.671244597865 14977.81428493851 17765.007444148767 18546.789220087656 14772.749454894194 16091.483719249149 0.6379274221979759 0.9982373778118668 0.8594718179942635 0.9405280551254699 0.7582688742369875 0.9307913767467924 1.104000585284606 1.1525841584080523 0.9180476898611007 1.0 13.974009735798168 -7.058129023404348 4.884302382236572 1.0541320366055775 0.8533053578172388 0.43659631314977665 0.10861781219585309 0.20297395794877868 10.037538982138777 0.04046855407612296 0.03176038385646355 8.747238672106554e-08 7.058129023404348 -0.2008266787883387 S(ph)PSEARQDVDLCLVSSCEYK ddPTM_PC-9_AZD4547_30min_R2 2 SPSEARQDVDLCLVSSCEYK 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.714)PS(0.286)EARQDVDLCLVSSCEYK;S(0.892)PS(0.108)EARQDVDLCLVSSCEYK 111.99 2.2292e-05 15892000.0 24513.0 19569.9 27855.5 50742.0 44960.3 34762.9 23001.3 30011.0 21315.0 29065.5 True False 32307.624097925614 25895.487464747406 27486.117869539637 39044.21585608509 38718.33841626927 32589.17036757727 25048.37114057765 25373.489534173423 22441.66738456507 28047.925691849654 1.1518721367446354 0.9232585592692255 0.9799697193838021 1.3920535972979566 1.3804350040587954 1.1619101792275226 0.8930561003253216 0.9046476310918997 0.8001186123751859 1.0 14.775606458592467 -7.2606374155307964 8.274490923036975 0.8911996270027058 1.1658223131590282 0.4443853094252448 0.14530327632679463 0.12257057733521957 104.7085520847873 0.0663147296813633 0.04799439954550192 5.48734902402325e-08 7.2606374155307964 0.27462268615632235 S(ph)PSEARQDVDLCLVSSCEYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSEARQDVDLCLVSSCEYK 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.655)PS(0.345)EARQDVDLCLVSSCEYK;S(0.5)PS(0.5)EARQDVDLCLVSSCEYK 105.16 0.00057629 3154000.0 9950.8 2422.83 7061.0 7443.8 11415.9 11452.7 12188.8 8456.900000000001 12388.5 9311.3 True False 11635.273902741352 2663.3525504743525 7229.361018991622 7026.74801912521 9179.036344723836 10852.100250673919 11034.188624729892 8234.915335826221 12569.658375760602 10999.364981789759 1.0578132394010369 0.242136937439909 0.6572525805771833 0.6388321535614554 0.8345060246587319 0.9866115242689331 1.003165968489798 0.748671886918901 1.1427621864144502 1.0 13.425132615656873 -6.399046284237381 2.429848561967857 0.9621567788946961 0.6145861458894345 0.3559462231723113 0.20487674536310838 0.31384570802081824 3.6286151068456927 0.06708422652212574 0.07780745384141385 3.9898237918955347e-07 6.399046284237381 -0.3475706330052616 S(ph)PSEARQDVDLCLVSSCEYK ddPTM_PC-9_Lapatinib_30min_R1 2 SPSEARQDVDLCLVSSCEYK 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.824)PS(0.176)EARQDVDLCLVSSCEYK;S(0.5)PS(0.5)EARQDVDLCLVSSCEYK 130.01 1.5951e-05 9430900.0 39752.5 27814.1 42940.7 31042.8 32004.3 31564.9 21699.5 22996.9 37545.8 22110.0 True False 39185.6220602843 27749.698160343192 39410.281401895474 33325.7910677451 30121.869996874728 30214.94280837575 22822.993933531063 24065.419928310956 33316.996629198264 25931.68404027687 1.5111098068070523 1.0701078309161334 1.519773314401169 1.285137942294213 1.1615855703813798 1.1651747245356745 0.8801200067871637 0.9280315112174262 1.2847988035582492 1.0 14.662428279441581 -6.566653920245406 1.6561422161237886 1.0249797691202316 1.342027642268168 0.4463509699977982 0.1570624805793211 0.3476421485174059 1.948311654420757 0.061261420783401396 0.06490743475167424 2.712352184939864e-07 6.566653920245406 0.3170478731479365 S(ph)PSFASEWDEIEK ddPTM_PC-9_AZD4547_30min_R2 2 SPSFASEWDEIEK 13 0 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 S(0.71)PS(0.29)FASEWDEIEK;S(0.988)PS(0.012)FASEWDEIEK 166.86 9.599299999999999e-05 21664000.0 19466.7 18690.2 19411.6 23670.0 24073.6 22862.0 17553.1 21242.2 20213.0 22656.0 True False 25656.705667486192 24731.4416432185 19154.18950068588 18213.24719785454 20731.396180583743 21432.435525906967 19115.291895139537 17959.706087195304 21281.417914342648 21862.82033594969 1.1735313776191127 1.131210029776069 0.8761078948807932 0.8330694264502532 0.9482489387014028 0.9803143051340439 0.8743287280144588 0.8214725186971243 0.9734067968966005 1.0 14.416191902344762 -5.220100827024183 5.7917485756922975 0.9062897072207914 1.1574798339520291 0.7183671464189634 0.059783231794098335 0.10042857635864148 9.035822317917866 0.015522576493272919 0.04142264010594254 6.024197103895617e-06 5.220100827024183 0.25119012673123775 S(ph)PSFASEWDEIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPSFASEWDEIEK 13 0 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 S(0.815)PS(0.185)FASEWDEIEK;S(0.834)PS(0.166)FASEWDEIEK;S(0.955)PS(0.045)FASEWDEIEK 159.52 0.0002585 44396000.0 45857.1 41934.6 43814.4 57127.2 61584.4 52891.9 54665.7 45567.6 52614.5 40935.2 True False 53619.80131099009 46097.589951883456 44859.1014630373 53926.54819288134 49517.37890731444 50118.1556531315 49487.369150605206 44371.49878286309 53383.887525645274 48356.42771713508 1.1088453767644615 0.9532877453548703 0.927676083217816 1.1151888329785058 1.0240082083186635 1.0364321356883885 1.0233876133300348 0.917592569956115 1.1039667329836427 1.0 15.561420050415808 -4.033160510555952 4.50699538857237 1.0115294436356264 16.869728656602128 0.17618450142427067 0.06298355252154098 1690.32644220595 177.59033428967453 0.015734492251691354 273318.8964057832 9.264873403668803e-05 4.033160510555952 15.8581992129665 S(ph)PSFASEWDEIEK ddPTM_PC-9_Lapatinib_30min_R1 1 SPSFASEWDEIEK 13 0 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 S(0.956)PS(0.044)FASEWDEIEK 121.76 0.00019226 16636000.0 43961.0 48752.0 48724.0 53701.0 57443.0 45987.0 50447.0 44060.0 51828.0 42903.0 True False 43334.10807853997 48639.117739313944 44718.100800079046 57650.350681284544 54064.315677283215 44020.2432109329 53058.898820933246 46107.18844893798 45990.584866964775 50318.726385345944 0.8611924663331688 0.966620604957896 0.8886969924004686 1.1457036936863678 1.0744372833138336 0.8748282473173383 1.0544563154202826 0.9163027715734382 0.9139854716266899 1.0 15.618807786249981 -4.646536290101325 1.4541427759494805 0.9888233447327877 0.7856635819700519 0.163621824342563 0.08349365371699573 3.200719620008795 4.919925733112875 0.024691439603584605 1.0377548846185614 2.2566474197989364e-05 4.646536290101325 -0.20315976276273573 S(ph)PSFGAGEGLLR ddPTM_PC-9_AZD4547_30min_R2 2 SPSFGAGEGLLR 12 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 S(0.96)PS(0.04)FGAGEGLLR;S(0.812)PS(0.188)FGAGEGLLR 96.604 0.0042316 31433600.0 29284.0 35347.7 33637.0 39720.0 37278.0 47002.0 40892.0 50090.0 41043.0 42212.0 True False 38595.70285496077 46773.15276305203 33190.95140197463 30563.16766788265 32102.593165118666 44062.95750978386 44531.308781699314 42349.741453691866 43212.44918905484 40734.17072833282 0.947501867961568 1.148253466972356 0.8148183897822308 0.7503078403563599 0.7880998334106155 1.0817197630866628 1.0932175121150896 1.039661313744024 1.0608402826523786 1.0 15.313951917461376 -6.780137289806971 24.972189392458375 1.0599497636727966 0.8922402077915673 0.38006893990479873 0.10543618613674059 295.9711074392827 395284.7139732951 0.04178840576868236 0.03691644589563349 1.6590623593113147e-07 6.780137289806971 -0.16770955588122927 S(ph)PSFGAGEGLLR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSFGAGEGLLR 12 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 S(0.959)PS(0.041)FGAGEGLLR 138.2 6.8713e-05 20398000.0 7378.6 5991.7 11435.0 6660.8 5602.7 5944.7 10366.0 2051.7 8296.9 7535.9 True False 7273.379810930477 5977.826586778952 10494.858440376487 7150.657451777433 5273.160201332013 5690.459038772537 10902.700758772457 2147.0294720990914 7362.415751769708 8838.470274044434 0.8229229250552449 0.6763417651959283 1.1874066569184827 0.8090379024950133 0.5966145767121582 0.6438284977303674 1.2335506508168006 0.24291867320119673 0.8329966072738408 1.0 13.109580980181283 -5.9974669868596155 24.99835499478522 0.7352580444768183 0.8944000001866045 0.04474719320830023 0.2713719491567469 244.4393194733865 2412298.424944281 0.07509794389254923 0.11064370103045465 1.005849520315242e-06 5.9974669868596155 0.15914195570978618 S(ph)PSFGDPQLS(ph)PEAR ddPTM_PC-9_AZD4547_30min_R2 1 SPSFGDPQLSPEAR 14 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 2 S(1)PSFGDPQLS(1)PEAR 166.9 0.005058 2735700.0 7612.0 11233.0 10392.0 5877.0 8774.9 9364.5 10352.0 11922.0 9422.8 8226.7 True False 10032.457660564183 14863.847576712573 10254.19528998782 4522.1484487448715 7556.65660079939 8778.936334631957 11273.30794551872 10079.728840305732 9920.86997097253 7938.685737012596 1.2637428905630788 1.8723310216718545 1.291674167448096 0.5696343952326043 0.9518775337796697 1.1058425318062226 1.4200471361347746 1.269697425269139 1.2496866987338193 1.0 12.95468447116944 -5.517285211063706 24.98136809640594 1.0888127090966984 1.57152843467377 0.3677187677799214 0.2549519916053264 251.56393481636675 1123511.8358600752 0.07307817236994514 0.1318289087841337 3.0388886629192654e-06 5.517285211063706 0.48271572557707154 S(ph)PSFGDPQLS(ph)PEAR ddPTM_PC-9_Lapatinib_30min_R1 2 SPSFGDPQLSPEAR 14 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 2 S(1)PS(0.001)FGDPQLS(1)PEAR;S(1)PSFGDPQLS(1)PEAR 133.78 0.00016484 5454500.0 7505.599999999999 16636.0 15401.7 12723.7 16080.9 14291.5 16821.9 15010.199999999999 13111.4 14634.8 True False 7398.568767641536 16597.480364112787 14135.431678281288 13659.44334301894 15135.053078265826 13680.285860113678 17692.855671811165 15707.628689429146 11634.656062837119 17164.405680354765 0.4310413599760955 0.9669708740984349 0.8235316702202955 0.7958005419699808 0.8817697134476611 0.7970148291106416 1.0307875496126981 0.9151280260992113 0.677836231530776 1.0 14.067132284217244 -4.753857173338822 24.997462503252763 0.8722047119774877 0.43104057381688815 0.631718796855105 0.10199707021499321 176.27406478737026 581102.892810732 0.02471682071610599 0.25562535956308374 1.762555603721522e-05 4.753857173338822 -0.4411641381605996 S(ph)PSFGDPQLS(ph)PEARPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSFGDPQLSPEARPR 16 1 O95425-2;O95425-3 O95425-2 SVIL Supervillin 2 S(0.998)PS(0.005)FGDPQLS(0.997)PEARPR 111.58 0.013215000000000001 6893600.0 14544.0 12775.0 16839.0 14422.0 18209.0 15329.0 18413.0 14867.0 14804.0 12296.0 True False 17006.011942906123 14043.217572966265 17240.505622263117 13613.982096754857 14641.077164400207 14525.120254837764 16668.78734142422 14476.757002888586 15020.480493583567 14525.167464917558 1.1707962737077224 0.9668196670974472 1.1869402307342671 0.9372685120248372 1.0079799217298253 0.9999967497738041 1.1475797013483058 0.9966671322622683 1.0341003317078672 1.0 13.82626717652957 -4.742057859611827 24.50457544933936 1.0346402874390475 1.1707968644123325 0.24280404221726648 0.0738814207623393 1548.1543975643767 1957241.7285530325 0.017622632168866226 0.6268455191081399 1.811098789867632e-05 4.742057859611827 0.1361565769732851 S(ph)PSFGDPQLS(ph)PEARPR ddPTM_PC-9_Lapatinib_30min_R1 2 SPSFGDPQLSPEARPR 16 1 O95425-2;O95425-3 O95425-2 SVIL Supervillin 2 S(0.94)PS(0.06)FGDPQLS(1)PEARPR;S(0.939)PS(0.061)FGDPQLS(1)PEARPR 112.53 0.0010815 32630000.0 28918.0 26161.0 30265.0 23549.0 29984.0 28607.0 20264.4 25083.0 26748.0 21627.6 True False 28505.624017088285 26100.42581182705 27776.728526278468 25280.872017161124 28220.400070812102 27383.545296174067 21313.591477529295 26248.447749993436 23735.35857107307 25365.901843034455 1.1237772736598366 1.0289571399171167 1.095042025241694 0.9966478690014847 1.1125328894451076 1.0795415619608124 0.8402457602106532 1.0347926090868056 0.9357190892698681 1.0 14.630602833586183 -7.205115119712082 24.999849073606995 0.9555884540269735 1.07012171000089 0.5006889614313015 0.05867259936375212 237.28365138093685 105319.66239090044 0.021055082367026554 0.01630919075501544 6.235695221712048e-08 7.205115119712082 0.1145332559739165 S(ph)PSFGDPQLSPEAR ddPTM_PC-9_Lapatinib_30min_R1 2 SPSFGDPQLSPEAR 14 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 S(0.985)PS(0.015)FGDPQLSPEAR;S(0.939)PS(0.06)FGDPQLS(0.001)PEAR 124.16 3.8967e-05 9036000.0 11685.0 16474.0 17977.800000000003 15409.0 21305.6 20315.0 17585.9 21211.0 21880.5 15877.4 True False 11518.369757233433 16435.855465159548 16499.73468031486 16542.22926291713 20052.446496421246 19446.174806577983 18496.411853530437 22196.540494562472 19416.087678120384 18621.78743469435 0.6185426505177208 0.8826142776465067 0.8860446258544504 0.8883266077936868 1.0768271610200764 1.0442700452238927 0.9932672638647821 1.1919661618093642 1.042654350244927 1.0 14.18470393791364 -4.0961940500493235 0.5008769315148681 1.0785386765978797 1.3498840339020206e-17 0.7815003478735862 0.06889379540339889 3.8093549976817545 0.4386049685876901 0.0405805219272525 2.793065354397877 8.013199402138296e-05 4.0961940500493235 -1.0785386765978797 S(ph)PSGAGEGASCSDGPR ddPTM_PC-9_AZD4547_30min_R2 2 SPSGAGEGASCSDGPR 16 0 Q7Z2K8;Q7Z2K8-2 Q7Z2K8 GPRIN1 G protein-regulated inducer of neurite outgrowth 1 1 S(0.997)PS(0.003)GAGEGASCSDGPR;S(0.992)PS(0.008)GAGEGASCSDGPR 155.37 1.0297e-14 3849500.0 1431.65 2151.0 3126.7 2760.76 3939.08 2296.35 1925.4 5938.299999999999 3792.04 1792.3 True False 1886.884919830099 2846.2686849024103 3085.237915050514 2124.3094353168085 3392.206735470135 2152.7588714861536 2096.7568700059637 5020.67218355876 3992.479492796904 1729.552122533663 1.0909673638895343 1.645668059273543 1.7838363324551758 1.2282425072017233 1.9613209057272059 1.2446915264586098 1.212312044654875 2.902874170802008 2.3083892302408464 1.0 10.756182776712182 -7.73749176760277 24.999968437942535 2.20422466779775 1.4755720887027297 0.2199364198297169 0.5138809361238644 265.32814166407525 276988.1676728331 0.23014533232188167 0.13278767558191143 1.830240799651892e-08 7.73749176760277 -0.7286525790950202 S(ph)PSGAGEGASCSDGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSGAGEGASCSDGPR 16 0 Q7Z2K8;Q7Z2K8-2 Q7Z2K8 GPRIN1 G protein-regulated inducer of neurite outgrowth 1 1 S(0.985)PS(0.015)GAGEGASCSDGPR;S(1)PSGAGEGASCSDGPR 128.74 1.9882e-05 3751600.0 1070.5 1872.6599999999999 2149.1 459.47 1042.0 1237.7 2174.73 1702.6 745.39 728.53 True False 1251.7145066612347 2058.5653088212116 2200.3426945071365 433.7273855218388 837.8275800595868 1172.7928331536755 1968.7238307182702 1657.9085540538167 756.2899186106637 860.606721959693 1.454455879464836 2.391993062909896 2.5567342647483886 0.5039786170089346 0.9735312991185617 1.3627511884674819 2.2875998763236205 1.9264415577403144 0.8787869061590771 1.0 9.749210298594576 -1.5228787452803376 0.22291283681097868 1.2689906505052302 5.263295606289328 0.09074761478276394 0.648779576735568 148.65302442734216 1.9141264687729327 1.0909280715972034 214.47775546920334 0.029999999999999995 1.5228787452803376 3.994304955784098 S(ph)PSGAGEGASCSDGPR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSGAGEGASCSDGPR 16 0 Q7Z2K8;Q7Z2K8-2 Q7Z2K8 GPRIN1 G protein-regulated inducer of neurite outgrowth 1 1 S(1)PSGAGEGASCSDGPR 155.06 3.733e-05 2677600.0 0.0 1340.5 984.91 590.69 0.0 703.66 710.22 793.16 1058.2 0.0 True False 0.0 1337.396154610074 903.934501662545 634.1313130840754 0.0 673.5661021115759 746.9917164668506 830.0131091729378 939.0143726599935 0.0 0.0 S(ph)PSGHPHVR ddPTM_PC-9_AZD4547_30min_R2 10 SPSGHPHVR 9 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;Q8WX93-4;Q8WX93-7 Q8WX93-3 PALLD Palladin 1 S(1)PSGHPHVR;S(1)PSGHPHVR;S(0.991)PS(0.009)GHPHVR;S(0.988)PS(0.012)GHPHVR;S(1)PSGHPHVR;S(0.992)PS(0.008)GHPHVR;S(0.996)PS(0.004)GHPHVR;S(0.982)PS(0.018)GHPHVR;S(0.999)PS(0.001)GHPHVR;S(0.789)PS(0.211)GHPHVR 114.89 0.0011401 280092090.0 55101.86 48777.28999999999 125128.76 163556.32 139176.77000000002 133160.6 96233.59 129426.51000000001 148517.43 181538.6 True False 72623.1052901124 64543.59510060598 123469.4708847206 125850.93734395449 119854.47785142172 124834.04663157562 104798.19308083391 109426.61680482434 156367.7581454574 175182.98887004916 0.41455569264196235 0.3684352888195352 0.7048028560370684 0.7183970210561413 0.684167330541037 0.7125922867098562 0.5982212871055264 0.624641796047886 0.8925967021915072 1.0 17.418503163392167 -5.7988402823512155 0.12186030569424065 1.160717213894627 2.053229669364502e-16 0.6712135258030512 0.1037497960066808 18.75019063589169 0.5659840755693308 1.3849262269509859 4.273774732722973 1.5891310655123292e-06 5.7988402823512155 -1.1607172138946267 S(ph)PSGHPHVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 12 SPSGHPHVR 9 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;Q8WX93-4;Q8WX93-7 Q8WX93-3 PALLD Palladin 1 S(0.998)PS(0.002)GHPHVR;S(0.999)PS(0.001)GHPHVR;S(1)PSGHPHVR;S(1)PSGHPHVR;S(0.898)PS(0.102)GHPHVR;S(0.999)PS(0.001)GHPHVR;S(0.999)PS(0.001)GHPHVR;S(0.997)PS(0.003)GHPHVR;S(0.996)PS(0.004)GHPHVR;S(0.992)PS(0.008)GHPHVR;S(0.945)PS(0.055)GHPHVR;S(0.966)PS(0.034)GHPHVR 112.83 0.0012137 271260810.0 65492.11 114718.57 197096.0 176174.59999999998 288202.98 257656.2 157365.62999999998 214709.7 253559.16999999998 183132.33000000002 True False 76578.63069486526 126107.07148098298 201795.5161307423 166304.10832775963 231731.67495140297 244144.25529418304 142458.81829790055 209073.7978787314 257266.993174429 216332.77175427304 0.35398534430950207 0.5829309653750696 0.9328014174383008 0.7687420957036518 1.0711815554909137 1.128558809256604 0.6585170482617213 0.9664453341179998 1.189218772025221 1.0 17.722892706847418 -4.782907291006955 1.0146806905880486 0.9800066568000698 4.6860195291435294e-18 0.661160761519056 0.14758295769213212 1.2082856920264102 0.9968684475879744 0.04995318946612319 1.2979378960728203 1.6485142628761685e-05 4.782907291006955 -0.9800066568000698 S(ph)PSGHPHVR ddPTM_PC-9_Lapatinib_30min_R1 10 SPSGHPHVR 9 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;Q8WX93-4;Q8WX93-7 Q8WX93-3 PALLD Palladin 1 S(1)PSGHPHVR;S(1)PSGHPHVR;S(1)PSGHPHVR;S(0.999)PS(0.001)GHPHVR;S(0.999)PS(0.001)GHPHVR;S(0.998)PS(0.002)GHPHVR;S(0.997)PS(0.003)GHPHVR;S(0.995)PS(0.005)GHPHVR;S(0.999)PS(0.001)GHPHVR;S(0.989)PS(0.011)GHPHVR 111.27 0.0012732000000000002 289039080.0 78723.37999999999 58201.899999999994 84353.65000000001 64581.0 91974.56000000001 80765.58 66309.4 87646.7 122322.8 63477.399999999994 True False 77600.77016510027 58067.13707646406 77418.41851150544 69330.50217590058 86564.7972097423 77311.4244171627 69742.5762776139 91719.0856520093 108545.51814781124 74449.38401168119 1.042329244160363 0.7799545670835001 1.039879906855353 0.9312434628743542 1.1627335586303869 1.0384427681098403 0.9367784193710886 1.231965675332095 1.457977384081248 1.0 16.18397229166147 -7.8093192057739085 6.748625241405663 1.262674213354379 0.9903182660675903 0.3759402288274193 0.1398580752165787 0.19428959714160474 20.480263158283805 0.07452699372119855 0.03589127734314826 1.5512464271163797e-08 7.8093192057739085 -0.2723559472867886 S(ph)PSGLRPR ddPTM_PC-9_AZD4547_30min_R2 2 SPSGLRPR 8 1 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4 P49815 TSC2 Tuberin 1 S(0.998)PS(0.002)GLRPR;S(0.999)PS(0.001)GLRPR 65.157 0.024793 8229000.0 2915.77 1865.4 5169.0 7822.8 5279.0 5864.1 3513.4 5864.9 4335.7 4513.700000000001 True False 3842.9242082164005 2468.354070114808 5100.455682635397 6019.374321055193 4546.1019721729 5497.41689998561 3826.0857936423363 4958.614466994558 4564.876250493021 4355.676736863355 0.8822794804060227 0.5666981778570508 1.1709904087851062 1.3819607571221904 1.0437188631786931 1.2621269281669545 0.878413625433004 1.138425729583733 1.04802916429935 1.0 12.088681170895535 -5.271348660548576 24.985999230877503 1.1241300947597035 0.7244888261528324 0.5193852449534903 0.1502524648158608 444.68145356656595 1121254.2011643895 0.03877051012342286 0.08226943854423714 5.353666815489724e-06 5.271348660548576 -0.3996412686068711 S(ph)PSGLRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPSGLRPR 8 1 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4 P49815 TSC2 Tuberin 1 S(0.985)PS(0.015)GLRPR;S(0.992)PS(0.008)GLRPR;S(1)PSGLRPR 70.908 0.017388999999999998 13638600.0 14508.0 18213.9 18906.0 17794.870000000003 19856.6 15815.9 16842.5 13034.099999999999 14794.400000000001 14418.45 True False 16963.917853938525 20022.0556205284 19356.79074140427 16797.881125646945 15965.841771795773 14986.486361699288 15247.05647085957 12691.968685770495 15010.74011174499 17032.400848612604 0.9959792518222904 1.1755275018764793 1.1364687170911083 0.9862309650265916 0.9373805791504896 0.8798810276309362 0.8951795232145173 0.7451661570543847 0.8813050048060435 1.0 14.055994187922261 -6.169069826640678 1.636951104138138 0.8659203735641198 1.1099997336756497 0.6173214601132404 0.07437357938988627 0.22516044561051685 1.1988334300073034 0.025942358182963032 0.037713447245623054 6.775325639598909e-07 6.169069826640678 0.24407936011152997 S(ph)PSGLRPR ddPTM_PC-9_Lapatinib_30min_R1 3 SPSGLRPR 8 1 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4 P49815 TSC2 Tuberin 1 S(1)PSGLRPR;S(0.972)PS(0.028)GLRPR;S(1)PSGLRPR 86.882 0.0057294 15533900.0 16020.0 13455.5 12686.310000000001 12576.499999999998 15504.1 10992.9 15502.9 14169.25 16369.800000000001 14514.61 True False 15791.551862291803 13424.344616453463 11643.290562372766 13501.417763974134 14592.179320233385 10522.759292701507 16305.564305727721 14827.605082390248 14526.06074236399 17023.440998997878 0.9276357149662872 0.7885799714196277 0.683956349545205 0.7931074431290903 0.857181536981412 0.6181335073984721 0.9578301065388357 0.8710110419663749 0.8532975644124533 1.0 14.055235062309547 -8.329179454854769 0.715526466960197 0.9901084466152807 0.7843904861797273 0.29330905372616456 0.09465135680580888 0.8462516637717867 0.9849058004122995 0.09197820343678184 0.03756643872314003 4.686197037508793e-09 8.329179454854769 -0.20571796043555346 S(ph)PSGPPAMDLEGPR ddPTM_PC-9_AZD4547_30min_R2 1 SPSGPPAMDLEGPR 14 0 O96018 O96018 APBA3 Amyloid beta A4 precursor protein-binding family A member 3 1 S(0.997)PS(0.003)GPPAMDLEGPR 99.834 0.009398100000000001 0.0 2185.7 2510.5 7092.1 5632.9 5518.4 2423.7 5248.0 7934.7 5452.7 1614.2 True False 2880.707134615755 3321.9700294967447 6998.0541201041815 4334.321932437464 4752.2654145176975 2272.1456558542864 5715.061833276878 6708.574436266892 5740.918590092325 1557.6873493242408 1.8493487386062866 2.132629523464955 4.492592254241579 2.7825365175609784 3.0508467675360755 1.4586660518492323 3.668940263112619 4.306752853309889 3.68553971538824 1.0 10.605189977083779 -5.0280646626561625 24.098961094155 3.141019712040618 1.9201675840318806 0.13662357755193177 1.0638054404190467 691.960600105906 594186.0868777938 0.26920820474630514 0.7164349032290338 9.374224225214043e-06 5.0280646626561625 -1.2208521280087374 S(ph)PSGPPAMDLEGPR ddPTM_PC-9_Lapatinib_30min_R1 2 SPSGPPAMDLEGPR 14 0 O96018 O96018 APBA3 Amyloid beta A4 precursor protein-binding family A member 3 1 S(0.996)PS(0.004)GPPAMDLEGPR;S(0.999)PS(0.001)GPPAMDLEGPR 170.0 0.00016723 7256700.0 3140.0 7780.2 5943.8 1622.7199999999998 4937.099999999999 9683.5 5360.1 7455.0 5537.8 2873.5 True False 3095.223024194524 7762.185424914065 5455.123707731506 1742.0602420352313 4646.70948471206 9269.359278341022 5637.619750829272 7801.386515815534 4914.074648380755 3370.180646301926 0.9184145744801214 2.303195656123494 1.6186443043394045 0.5169041143081695 1.3787716364138698 2.7504042812993483 1.6727945301731495 2.3148274037998338 1.4581042276689034 1.0 11.718610208573402 -6.590599612849051 24.999918109173464 1.9280677553258927 1.368016923841929 0.12809920665420904 0.619440800727252 100.13733381694786 36965.192256912356 0.2030863281283748 0.20308634679115609 2.5668493898796145e-07 6.590599612849051 -0.5600508314839636 S(ph)PSGPSGSLENGTK ddPTM_PC-9_AZD4547_30min_R2 1 SPSGPSGSLENGTK 14 0 Q14134-2;Q14134;E9PM74;E9PI31;E9PLI4;E9PJ94;E9PJD4 Q14134-2 TRIM29 Tripartite motif-containing protein 29 1 S(1)PSGPSGSLENGTK 147.1 0.00020136 11519000.0 12172.0 13849.0 18357.0 16361.0 14581.0 19540.0 13297.0 23744.0 18130.0 14123.0 True False 16042.442806671994 18325.418418044366 18113.574185749265 12589.224224930213 12556.679836380574 18318.160711058626 14480.407240297767 20074.910382840062 19088.314786871422 13628.558068706641 1.1771195988450178 1.3446336968048345 1.329089555507779 0.9237385320929214 0.9213505767138145 1.344101160130804 1.062504717468762 1.4730032540225426 1.4006114726620462 1.0 13.73434530947168 S(ph)PSGPSGSLENGTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPSGPSGSLENGTK 14 0 Q14134-2;Q14134;E9PM74;E9PI31;E9PLI4;E9PJ94;E9PJD4 Q14134-2 TRIM29 Tripartite motif-containing protein 29 1 S(0.996)PS(0.004)GPSGSLENGTK;S(0.999)PS(0.001)GPSGSLENGTK;S(0.999)PS(0.001)GPSGSLENGTK 191.63 1.2386e-06 20543800.0 92123.0 57142.0 77556.0 114402.0 113730.0 143656.0 103738.0 119317.7 119962.0 104086.0 True False 107717.6043878123 62814.680121678124 79405.22917276778 107992.42683628834 91445.42291763597 136122.4264680654 93911.1856419198 116185.73680255296 121716.21730419285 122955.96785567707 0.8760664997916066 0.5108713405062907 0.6458021563131595 0.8783016287834634 0.7437249652247261 1.1070827129582097 0.7637789956820203 0.9449377596614842 0.9899171177039621 1.0 16.90778223447729 -6.130143928793122 1.4748618425426567 0.9384524134412057 0.6656015485550967 0.41587770727988016 0.13103299637294108 0.38160831294127173 1.6657958643440915 0.04589725250292505 0.07113861166562724 7.410646056439927e-07 6.130143928793122 -0.272850864886109 S(ph)PSGPSGSLENGTK ddPTM_PC-9_Lapatinib_30min_R1 2 SPSGPSGSLENGTK 14 0 Q14134-2;Q14134;E9PM74;E9PI31;E9PLI4;E9PJ94;E9PJD4 Q14134-2 TRIM29 Tripartite motif-containing protein 29 1 S(0.999)PS(0.001)GPSGSLENGTK;S(1)PSGPSGSLENGTK 162.46 0.000545 19889800.0 23869.2 24394.0 28551.0 26062.0 24562.0 26804.0 23636.0 23155.0 29427.0 17281.6 True False 23528.820830924815 24337.517191762905 26203.64699004715 27978.68642028336 23117.31145074998 25657.65540317579 24859.756428163797 24230.865831483385 26112.62137995239 20268.70153371545 1.1608449999515953 1.2007437748925005 1.2928133036277318 1.3803886930666442 1.140542299283261 1.2658756339421262 1.2265095712624448 1.1954819005636435 1.2883223593043698 1.0 14.30696604847897 -10.741177317786502 4.139957278854949 0.9998616188566226 1.239909493655377 0.5313238658525075 0.06735252077744705 49006493.69163758 16.3153359844332 65058.00033646616 0.01648911688863141 1.8147745584714805e-11 10.741177317786502 0.24004787479875433 S(ph)PSGSAFGS(ph)QENLR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSGSAFGSQENLR 14 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 2 S(0.99)PS(0.01)GSAFGS(1)QENLR 117.3 0.0039164000000000004 0.0 20275.0 15956.0 16651.0 11742.0 19755.0 15191.0 16761.0 20557.0 20975.0 15432.0 True False 19985.87478202038 15919.054862333716 15282.019054718752 12605.545850163733 18593.049739824335 14541.316341950584 17628.802567797153 21512.15326701811 18612.5746234581 18099.40063815254 1.1042285422364349 0.8795349183429436 0.8443384043615841 0.6964620598315249 1.0272743341915538 0.8034142473921645 0.9739992456234494 1.1885561128290445 1.0283530927661668 1.0 14.143654302787096 -7.530533882468079 12.01049191168967 1.0813932860903956 0.8871060982254755 0.3270790374005502 0.11530276400301813 0.40789244085835724 617.7127289539869 0.052777998466728704 0.031101114731308378 2.9475835052296392e-08 7.530533882468079 -0.19428718786492016 S(ph)PSGSAFGSQENLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSGSAFGSQENLR 14 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 S(0.999)PS(0.001)GSAFGSQENLR 104.9 0.0010220000000000001 4056400.0 639.53 647.55 943.43 2745.1 993.39 1178.1 2599.4 1420.8 1120.2 759.14 True False 747.7897977067348 711.8344844911394 965.9249491781985 2591.300946734278 798.7423606097826 1116.3183620734796 2353.166013973719 1383.5055054620364 1136.5808057898084 896.7660726510659 0.8338738724761077 0.7937794550888592 1.0771203088924648 2.8896063597430057 0.890691993117558 1.2448267124706915 2.624057806978769 1.542771908589323 1.2674217284222071 1.0 9.808587887472092 -5.539365230547046 24.999994681355137 1.678738661813977 0.844231881505161 0.23417172919223816 0.6180722841508702 307.08373232633693 465657.91758641996 0.16625482009610976 0.2880547237944372 2.888249916460631e-06 5.539365230547046 -0.834506780308816 S(ph)PSGSAFGSQENLR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSGSAFGSQENLR 14 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 S(0.996)PS(0.003)GSAFGSQENLR 171.15 6.5204e-05 30972000.0 23206.0 25880.0 20607.0 16121.0 19874.0 11189.0 14254.0 10349.0 17055.0 14181.0 True False 22875.0781845408 25820.076450062454 18912.77200532036 17306.59211807952 18705.050393787355 10710.472552832927 14992.002374642352 10829.852320881948 15134.086302888103 16632.16695500526 1.3753516451839611 1.5524180655420967 1.1371201393351078 1.040549446437062 1.124630990320734 0.643961342007196 0.9013859958957832 0.6511389856883818 0.9099287148710152 1.0 14.0216885248178 -5.736410110890476 0.9299604623205731 0.8147608429608919 1.5179852613712028 0.7175103361326975 0.14429121408297868 0.3564734665500484 0.5630100621530237 0.05724996362181868 0.18872956740149424 1.8348048908249302e-06 5.736410110890476 0.7032244184103109 S(ph)PSGSQRPSVSDDTEHLVNGR ddPTM_PC-9_AZD4547_30min_R2 1 SPSGSQRPSVSDDTEHLVNGR 21 1 P16144-4;P16144-2;P16144-3 P16144-4 ITGB4 Integrin beta-4 1 S(0.448)PS(0.26)GS(0.219)QRPS(0.067)VS(0.005)DDTEHLVNGR 46.22 0.032438 25967000.0 3373.9 3199.1 3983.9 0.0 3533.9 3186.7 3055.1 10740.0 2597.5 0.0 True False 4446.730018520428 4233.146513189816 3931.070882965982 0.0 3043.278984554239 2987.4351452369756 3326.997981487077 9080.37978064784 2734.798547098649 0.0 0.0 S(ph)PSGSQRPSVSDDTEHLVNGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPSGSQRPSVSDDTEHLVNGR 21 1 P16144-4;P16144-2;P16144-3 P16144-4 ITGB4 Integrin beta-4 1 S(0.936)PS(0.053)GS(0.01)QRPS(0.001)VS(0.001)DDTEHLVNGR;S(0.806)PS(0.172)GS(0.02)QRPS(0.002)VSDDTEHLVNGR;S(0.919)PS(0.067)GS(0.01)QRPS(0.002)VS(0.001)DDTEHLVNGR 81.477 0.00035487 38631600.0 12532.7 9769.5 13787.3 10660.8 18266.6 11418.0 16706.7 11523.5 10184.8 11734.9 True False 14654.238577891883 10739.351395623786 14116.041520626419 10063.509938779927 14687.390857885277 10819.21997975977 15124.120429966431 11221.020335157506 10333.73343225141 13862.344476582704 1.0571255535199624 0.7747139319590197 1.0183011643140363 0.7259601689872843 1.0595170883753684 0.7804754814769171 1.0910218293532679 0.8094605031719477 0.7454535161572357 1.0 13.758883654246876 S(ph)PSGSQRPSVSDDTEHLVNGR ddPTM_PC-9_Lapatinib_30min_R1 2 SPSGSQRPSVSDDTEHLVNGR 21 1 P16144-4;P16144-2;P16144-3 P16144-4 ITGB4 Integrin beta-4 1 S(0.321)PS(0.321)GS(0.158)QRPS(0.158)VS(0.041)DDT(0.001)EHLVNGR;S(0.594)PS(0.337)GS(0.067)QRPS(0.002)VS(0.001)DDTEHLVNGR 65.02199999999999 0.0020948 45000000.0 40547.8 38703.7 42470.3 30320.5 40052.4 43295.1 35146.5 26108.9 42130.5 29725.8 True False 39969.58093644416 38614.08396059823 38978.555874098936 32550.370716222937 37696.59657804813 41443.469498807506 36966.213796854754 27322.014809225522 37385.31943616693 34863.86492286126 1.1464472176243123 1.1075675071032598 1.1180216525144793 0.9336420614364731 1.0812512227618618 1.1887227532146558 1.0603016584261409 0.7836771645850908 1.072322862622505 1.0 15.089444891525048 -7.545686535666363 24.99472841571681 0.9411978039276365 1.0923526951529234 0.32911114219571547 0.09158620549565133 257.0882373934861 281735.90360921837 0.04236700827841463 0.024462435464737045 2.846514918864733e-08 7.545686535666363 0.1511548912252869 S(ph)PSIVASNQGR ddPTM_PC-9_AZD4547_30min_R2 1 SPSIVASNQGR 11 0 Q8TED9;Q8TED9-4 Q8TED9 AFAP1L1 Actin filament-associated protein 1-like 1 1 S(0.719)PS(0.281)IVASNQGR 96.23 0.0058909 6285200.0 12425.0 10953.0 16903.0 23217.0 20489.0 15028.0 15291.0 15477.0 18735.0 20007.0 True False 16375.891543945078 14493.343052411015 16678.855175775992 17864.679349074293 17644.456015883807 14088.296784329013 16651.869377407904 13085.385276078834 19725.293851739436 19306.56101965685 0.8482034437553156 0.7506952189804654 0.8638957066871995 0.9253164937497407 0.9139098360354917 0.7297154977515212 0.8624979539574092 0.6777688301275424 1.0216886286302493 1.0 14.236803586731067 -8.29441993015345 24.894632505777558 1.010844480741236 0.8254013151601798 0.49686638632536195 0.07613281373071024 603.5230470121506 455550.4271417129 0.07392838437650733 0.019093710342889977 5.076683280102784e-09 8.29441993015345 -0.18544316558105622 S(ph)PSIVASNQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSIVASNQGR 11 0 Q8TED9;Q8TED9-4 Q8TED9 AFAP1L1 Actin filament-associated protein 1-like 1 1 S(0.744)PS(0.255)IVAS(0.001)NQGR;S(0.964)PS(0.036)IVASNQGR 105.36 0.0025681999999999996 11547500.0 23015.7 19019.4 26482.0 34129.0 39320.3 28908.6 23405.6 34008.1 28177.1 18130.7 True False 26911.803429204072 20907.52033716434 27113.431313544283 32216.862777710914 31615.76947813532 27392.582125318215 21188.45212613037 33115.423409560455 28589.136781663976 21417.652387457765 1.2565244286513724 0.976181700913581 1.2659385269237995 1.504220079534823 1.4761547580560044 1.2789722061863038 0.9892985348169338 1.5461742870078952 1.3348398911547303 1.0 14.386512732906239 -11.719969425322294 2.2325884792596007 0.1961954353281629 1.291819218153427 0.18467475528273103 0.18408351097587922 3275263.0232408512 644165.6216940654 13335355.364757057 0.04996078619767033 1.9055948686387547e-12 11.719969425322294 1.095623782825264 S(ph)PSKPLPEVTDEYKNDVK ddPTM_PC-9_AZD4547_30min_R2 1 SPSKPLPEVTDEYKNDVK 18 2 P05455;E9PGX9;E9PFL9;E7ERC4 P05455 SSB Lupus La protein 1 S(0.5)PS(0.5)KPLPEVTDEYKNDVK 55.782 0.012397 17501000.0 44982.0 39515.0 39940.0 36001.0 54397.0 60868.0 46625.0 45512.0 36278.0 47303.0 True False 59285.3403162767 52287.45099205887 39410.36950366761 27701.52565990541 46844.91551056816 57061.914337805356 50774.534675406685 38479.16616171737 38195.581016995115 45646.93636791261 1.298780269467354 1.1454755817701314 0.8633738129985656 0.6068649478824195 1.026244458839469 1.2500710645264 1.112331707568846 0.8429736850590961 0.836761107232699 1.0 15.478230415330941 -5.036664374598239 3.844751880839816 0.9457550224479613 1.278858431077729 0.3299489644980915 0.16590310143434486 0.27771099998292453 8.621562717679316 0.048242300210092355 0.17832617494391842 9.190425637654022e-06 5.036664374598239 0.3331034086297676 S(ph)PSKPLPEVTDEYKNDVK ddPTM_PC-9_Lapatinib_30min_R1 1 SPSKPLPEVTDEYKNDVK 18 2 P05455;E9PGX9;E9PFL9;E7ERC4 P05455 SSB Lupus La protein 1 S(0.5)PS(0.5)KPLPEVTDEYKNDVK 43.791000000000004 0.036923000000000004 9916600.0 29617.0 29850.0 29761.0 32144.0 37561.0 28804.0 32011.0 32315.0 31732.0 29020.0 True False 29194.656148907376 29780.884158978522 27314.16546078222 34507.97698924058 35351.73582776727 27572.12006540351 33668.37294897407 33816.472871707425 28158.008007226337 34036.068333280615 0.8577564207191556 0.8749801495097671 0.8025064820449402 1.0138649579422347 1.0386550961645646 0.8100853422733134 0.9891968901723291 0.9935481542867138 0.8272990796558402 1.0 15.0547767736921 -5.755968443167122 24.999852278220597 0.9520597526673784 0.8480709297245428 0.30713278632576935 0.0743864069935479 174.7667402353223 798598.0986256318 0.020349839583475623 0.03399493672242619 1.7540079474508047e-06 5.755968443167122 -0.10398882294283562 S(ph)PSKPTLAYPESNSR ddPTM_PC-9_AZD4547_30min_R2 1 SPSKPTLAYPESNSR 15 1 F5GXS6;F5H6R3;F5H0C6;F5H1B0;F5GYW0;Q86XR8-3;Q86XR8-2;Q86XR8-4;Q86XR8-5;Q86XR8 F5GXS6 CEP57 Centrosomal protein of 57 kDa 1 S(0.783)PS(0.211)KPT(0.007)LAYPESNSR 57.708 0.029044 11036000.0 14768.0 14571.0 14409.0 21623.0 22543.0 16601.0 16161.0 20035.0 15635.0 16822.0 True False 19463.916806517584 19280.79079856486 14217.927245326646 16638.1514220198 19413.29357050458 15562.936845664492 17599.297691994594 16939.05110849903 16461.43418051488 16233.06690021831 1.199028928184595 1.1877478801190404 0.87586204952654 1.0249542815471329 1.1959104025033926 0.9587182102634711 1.084163442445858 1.04349050075505 1.0140680305022027 1.0 13.986647972395366 -5.058428224251128 21.642928685375644 1.032077817269485 1.1962088314712451 0.42593822538896153 0.07802647769797322 51.89707735142746 19223.58268392054 0.019804775319537445 0.052399938082000115 8.741214465032113e-06 5.058428224251128 0.16413101420176002 S(ph)PSKPTLAYPESNSR ddPTM_PC-9_Lapatinib_30min_R1 2 SPSKPTLAYPESNSR 15 1 F5GXS6;F5H6R3;F5H0C6;F5H1B0;F5GYW0;Q86XR8-3;Q86XR8-2;Q86XR8-4;Q86XR8-5;Q86XR8 F5GXS6 CEP57 Centrosomal protein of 57 kDa 1 S(0.845)PS(0.154)KPTLAYPESNSR;S(0.995)PS(0.005)KPTLAYPESNSR 85.493 0.0028539000000000004 16818000.0 47598.5 38519.2 42869.2 34458.0 48106.6 34412.0 36434.7 33375.4 45627.6 33293.2 True False 46919.73666150413 38430.011159012596 39344.65985589749 36992.15626851832 45277.06436921455 32940.27897829 38321.110489643725 34926.14292688799 40488.53920807139 39047.885259599556 1.2015948200413582 0.9841765028636202 1.0076002732113378 0.9473536408588004 1.159526670092425 0.8435867591623785 0.9813876022958974 0.8944439038040279 1.0368945447082223 1.0 15.252956797107423 -6.764888032988221 24.999974960398493 0.9465481423996162 1.046660333330236 0.2692001370569639 0.08808209165454953 133.93923395525374 970945.2177217996 0.029493094056270625 0.02705358078930057 1.718351344353379e-07 6.764888032988221 0.10011219093061985 S(ph)PSLDNPTPFPNLGPSENPLKR ddPTM_PC-9_AZD4547_30min_R2 1 SPSLDNPTPFPNLGPSENPLKR 22 1 M0R0R8;M0R0X9;M0QXC8;M0QX56;M0R3C2;M0QYT9;M0R205;M0QZB8;M0QZB7;Q14653-3;Q14653-2;Q14653;Q14653-4 M0R0R8 IRF3 Interferon regulatory factor 3 1 S(0.745)PS(0.128)LDNPT(0.128)PFPNLGPSENPLKR 50.364 0.016821 15670000.0 15981.0 22445.0 24068.0 24695.0 25002.0 27762.0 27864.0 30426.0 32854.0 28430.0 True False 21062.62557455021 29699.907314102547 23748.842594248163 19001.949283946662 21530.90386593426 26026.037751300384 30343.84202027951 25724.360819924696 34590.59536722966 27434.674353418537 0.7677374006054375 1.0825682467195659 0.86565061018444 0.6926252901405004 0.7848062487846286 0.9486548816300191 1.1060398104014117 0.9376586901866861 1.2608349172156093 1.0 14.743712830826656 -7.031819728919144 4.002835392744131 1.0691312218974551 0.8460963734380098 0.45259546217054747 0.12264301239047205 0.22933521230438753 8.045045179647841 0.048911356491471325 0.03914710719678209 9.293520710173727e-08 7.031819728919144 -0.22303484845944532 S(ph)PSLDNPTPFPNLGPSENPLKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSLDNPTPFPNLGPSENPLKR 22 1 M0R0R8;M0R0X9;M0QXC8;M0QX56;M0R3C2;M0QYT9;M0R205;M0QZB8;M0QZB7;Q14653-3;Q14653-2;Q14653;Q14653-4 M0R0R8 IRF3 Interferon regulatory factor 3 1 S(0.696)PS(0.196)LDNPT(0.108)PFPNLGPSENPLKR 80.171 0.00023832 13015000.0 28227.0 32986.0 24898.0 33609.0 52106.0 35622.0 36043.0 23727.0 27829.0 32885.0 True False 33005.27359133738 36260.632083120545 25491.662746190817 31725.996691848137 41896.2033460507 33753.91961105293 32628.746111277538 23104.191390834556 28235.9464777045 38846.79018248323 0.8496267886302766 0.9334267236182403 0.656210271851122 0.8166954474955309 1.0784984589265372 0.8688985486958772 0.8399341607891834 0.5947516199485816 0.7268540423820302 1.0 15.245507776660586 -7.545764091230044 24.922070615463404 0.7399502155701445 0.8668222128827854 0.07021136038785936 0.1361224090274229 450.87898755941444 490999.60797276144 0.06449502400046221 0.03723883698284533 2.8460066384981007e-08 7.545764091230044 0.12687199731264087 S(ph)PSLESLSRPPSLGFGDTR ddPTM_PC-9_AZD4547_30min_R2 1 SPSLESLSRPPSLGFGDTR 19 1 Q5M775;Q5M775-4;J3KSG2 Q5M775 SPECC1 Cytospin-B 1 S(0.794)PS(0.151)LES(0.027)LS(0.027)RPPSLGFGDTR 56.121 0.013869 6262700.0 5874.2 6867.5 7717.7 10689.0 9549.7 11756.0 6375.9 14195.0 6946.8 11564.0 True False 7742.073409049673 9087.285073717936 7615.358255344398 8224.816193403762 8223.888994820903 11020.895461576514 6943.342748245052 12001.488918649551 7313.993665826715 11159.147879807662 0.6937871504560718 0.8143350345021652 0.6824318789720757 0.737046975449305 0.7369638867947907 0.9876108445088971 0.6222108375146586 1.0754843513066168 0.6554258214519493 1.0 13.445939245738815 -6.591141103795011 24.99996256322487 0.8580265652842287 0.7345973033767641 0.19084184827136708 0.13843531198900078 91.40448294778372 33473.802512604 0.04181324715524054 0.04181324643138157 2.563650962033224e-07 6.591141103795011 -0.12342926190746462 S(ph)PSLGSDLTFATR ddPTM_PC-9_AZD4547_30min_R2 6 SPSLGSDLTFATR 13 0 Q13425 Q13425 SNTB2 Beta-2-syntrophin 1 S(0.976)PS(0.021)LGS(0.002)DLTFATR;S(0.841)PS(0.069)LGS(0.089)DLT(0.001)FATR;S(0.998)PS(0.002)LGSDLTFATR;S(0.643)PS(0.261)LGS(0.092)DLT(0.005)FATR;S(0.886)PS(0.012)LGS(0.101)DLTFATR;S(0.737)PS(0.052)LGS(0.21)DLTFATR 159.12 0.00014297 98766700.0 569749.6699999999 635853.0700000001 675669.8 648360.1 625313.8 761955.8 669406.2 756691.8 690258.9299999999 701257.1 True False 750918.2135306658 841380.1400930082 666709.9769771956 498890.69600868947 538499.7725718748 714310.5833737579 728982.0549883578 639762.4693577313 726744.6078482656 676706.3023750477 1.1096663514070364 1.243346097324647 0.9852279705940852 0.7372337072341786 0.7957658598447996 1.0555695740777495 1.0772502818871894 0.9454064002542107 1.073943903429889 1.0 19.368170299311892 -5.349922678752035 5.905912015003351 0.9491595262144218 1.1751117342999415 0.3798184953930537 0.11127935831449547 0.22980180185791182 12.157742644840166 0.0322597208314182 0.06866935935849854 4.467631262205295e-06 5.349922678752035 0.22595220808551975 S(ph)PSLGSDLTFATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSLGSDLTFATR 13 0 Q13425 Q13425 SNTB2 Beta-2-syntrophin 1 S(0.993)PS(0.007)LGSDLTFATR;S(0.988)PS(0.012)LGS(0.001)DLTFATR 164.22 8.0083e-05 19942400.0 61443.0 76001.0 68788.0 82437.0 95449.0 81988.0 108529.0 79920.0 83371.0 78634.0 True False 71844.08634543324 83545.8770068891 70428.16679994267 77818.32215436005 76746.45363637959 77688.40494837481 98248.34743808342 77822.18468223965 84590.14315256379 92889.72173359872 0.7734341863083313 0.8994092720666436 0.7581911699760041 0.8377495453968266 0.8262103944770456 0.8363509277289016 1.0576880370021224 0.8377911272619405 0.9106512709249195 1.0 16.503231350491944 -7.03467877788383 24.803171505379492 0.939301562412941 0.8221447338139616 0.4903155951802508 0.06443406685641265 520.3777255179725 372186.2774453893 0.023620918277247993 0.01830668973521662 9.232540514615388e-08 7.03467877788383 -0.11715682859897947 S(ph)PSLGSDLTFATR ddPTM_PC-9_Lapatinib_30min_R1 4 SPSLGSDLTFATR 13 0 Q13425 Q13425 SNTB2 Beta-2-syntrophin 1 S(0.993)PS(0.007)LGSDLTFATR;S(0.999)PS(0.001)LGSDLTFATR;S(0.976)PS(0.021)LGS(0.003)DLTFATR;S(0.983)PS(0.014)LGS(0.002)DLTFATR 127.3 0.00011882 68408700.0 284222.6 432626.36 401363.83999999997 403167.3 522008.8 614019.94 675674.3 674994.8 600551.8200000001 552533.12 True False 280169.53360395855 431624.6402439036 368365.2543844256 432817.5681686874 491305.2686927879 587759.7385165893 710657.4091542598 706357.5225976662 532911.3499405762 648037.7335878958 0.4323352161189517 0.6660486232093162 0.5684317984771527 0.6678894541717033 0.7581429957367604 0.9069838190785988 1.0966296749722688 1.0899944339458134 0.8223461726373307 1.0 19.305718294452895 -6.535298962215724 1.384297043518911 1.0117401257604732 0.5671239005661207 0.8151491417841271 0.09120186334194304 0.17007997615411372 0.672819547959599 0.03861651100004684 0.042527475089140836 2.915419389349548e-07 6.535298962215724 -0.4446162251943525 S(ph)PSLLQSGAK ddPTM_PC-9_AZD4547_30min_R2 2 SPSLLQSGAK 10 0 Q9BQG0;Q9BQG0-2;I3L1L3;I3L2H8 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 S(0.998)PS(0.002)LLQSGAK;S(0.971)PS(0.029)LLQSGAK 94.538 0.006263899999999999 29733000.0 150774.0 172554.0 165035.0 168039.0 172698.0 148697.0 133538.0 202329.0 135827.0 152619.0 True False 198716.9957059777 228328.70602261776 162846.5280680466 129300.20472667007 148721.86368446998 139398.95308353525 145422.623302616 171063.70210788597 143006.53792368376 147275.855263608 1.3492842757578665 1.5503471741103374 1.1057245451168405 0.8779457060034488 1.009818367160549 0.9465159977107317 0.9874165934553568 1.161518986270358 0.9710114238869458 1.0 17.168161405512265 -5.390041160438164 4.559247620216161 0.9983020318261807 1.4460787517057432 0.8273660805742619 0.08193953081340927 0.08043910216385851 2.5889088756180563 0.021703375976000312 0.047323287284801056 4.0734167000027705e-06 5.390041160438164 0.44777671987956247 S(ph)PSLLQSGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSLLQSGAK 10 0 Q9BQG0;Q9BQG0-2;I3L1L3;I3L2H8 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 S(0.993)PS(0.007)LLQSGAK 84.605 0.012437 15495000.0 59413.0 78176.0 62754.0 70279.0 68638.0 61794.0 59227.0 46694.0 55979.0 53803.0 True False 69470.44743976081 85936.7966328147 64250.293355870286 66341.49547759235 55188.87662200577 58553.41385788016 53616.58979365295 45468.33197638254 56797.586973136655 63557.05799568634 1.0930406414418337 1.3521204307261563 1.0109072915274178 1.0438100436004292 0.868335923065405 0.9212731945813826 0.8435977291033822 0.7153939060468865 0.893647200866213 1.0 15.955764724606125 -5.830159921383863 1.1843910735003333 0.8515101557313995 1.2244358907811548 0.6255080031584301 0.10024535053850948 0.29597092086310867 0.8257761641230235 0.035205146292175825 0.08546910799014203 1.47856383251656e-06 5.830159921383863 0.37292573504975524 S(ph)PSLSLAPLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 SPSLSLAPLSPR 12 0 G3V160;Q969H4-2;Q969H4 G3V160 CNKSR1 Connector enhancer of kinase suppressor of ras 1 2 S(0.999)PS(0.001)LSLAPLS(1)PR;S(1)PSLSLAPLS(1)PR 185.32 0.0052822 10921800.0 19029.4 24686.0 25241.0 26007.0 28878.0 27256.1 18452.3 27222.0 23663.7 22002.1 True False 25080.35336389123 32665.26673895904 24906.287847823576 20011.48795414459 24868.788170564334 25551.77175827456 20094.518953158335 23015.465399329187 24914.514871598985 21231.81317591803 1.1812629075098668 1.538505753997934 1.1730645725572455 0.9425237396513276 1.1712983702574922 1.2034663053297965 0.9464344277459233 1.0840084739175384 1.1734520582471037 1.0 14.373939960788316 -5.510254835297032 23.844875262754655 1.0801671409607416 1.3588596254502714 0.47811975994493994 0.1180231575780754 248.47936541489503 469342.4065664775 0.030042895002495407 0.057935696951265006 3.088482641002193e-06 5.510254835297032 0.27869248448952977 S(ph)PSLSLAPLS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSLSLAPLSPR 12 0 G3V160;Q969H4-2;Q969H4 G3V160 CNKSR1 Connector enhancer of kinase suppressor of ras 1 2 S(1)PS(0.001)LS(0.002)LAPLS(0.998)PR;S(1)PSLSLAPLS(1)PR 100.18 0.024502 2226100.0 10112.4 11602.8 13316.1 11596.9 20561.2 18893.0 23912.0 16231.1 18219.8 19104.3 True False 11824.229590995858 12754.649303766178 13633.606325590463 10947.16329065708 16532.380459809192 17902.217820774327 21646.882252111867 15805.050823272004 18486.230106524854 22567.75836044441 0.5239434684714078 0.5651712988083859 0.6041187657116507 0.48507978133285473 0.7325663539887189 0.793265220889302 0.9591950563443373 0.7003376485532684 0.8191433908175192 1.0 14.461975503312669 -6.50935499259974 2.6676288486227495 0.8432043518378998 0.550321504240226 0.748197170305446 0.08431913821609019 0.1458575539519834 2.087649271958015 0.028714758793698766 0.03095999276940634 3.0948885010903925e-07 6.50935499259974 -0.2928828475976738 S(ph)PSLSLAPLSPR ddPTM_PC-9_AZD4547_30min_R2 2 SPSLSLAPLSPR 12 0 G3V160;Q969H4-2;Q969H4 G3V160 CNKSR1 Connector enhancer of kinase suppressor of ras 1 1 S(1)PSLSLAPLSPR;S(0.999)PS(0.001)LSLAPLSPR 138.42 6.3216e-05 6819000.0 5444.7 5405.2 7081.900000000001 10713.5 9199.5 7385.700000000001 8118.799999999999 8786.3 6996.099999999999 8233.6 True False 7176.001343204656 7152.325195553 6987.98937876874 8243.66809692499 7922.308219928894 6923.87101144655 8841.357471800358 7428.579224088093 7365.899563178776 7945.3441701127895 0.9031706103050773 0.9001907333929209 0.8795074485325336 1.0375470112338716 0.9971006982591707 0.8714375190305018 1.1127721194329143 0.9349600300552668 0.9270711759581601 1.0 12.955893999108202 -5.743826405970453 24.99626713813215 0.9816223392470134 0.8948796793552287 0.29990090935972147 0.06207439976217012 314.85688892918114 446840.2236138621 0.01666535219572712 0.02878293029384346 1.8037385781954916e-06 5.743826405970453 -0.08674265989178465 S(ph)PSLSLAPLSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPSLSLAPLSPR 12 0 G3V160;Q969H4-2;Q969H4 G3V160 CNKSR1 Connector enhancer of kinase suppressor of ras 1 1 S(0.93)PS(0.048)LS(0.021)LAPLSPR;S(0.994)PS(0.005)LSLAPLSPR;S(1)PSLSLAPLSPR 121.21 0.00045738 26774900.0 30843.5 32163.1 40312.0 38226.8 40717.7 26534.3 27547.9 26653.9 24577.5 26429.4 True False 36064.69536310675 35356.04000947718 41273.19096411136 36085.076328957766 32739.358979455126 25142.794597034488 24938.36348247545 25954.263367141455 24936.89944143814 31220.841004984715 1.1551481062713418 1.1324499555867904 1.3219756302375612 1.1558009062983419 1.0486379586708752 0.8053208622093233 0.7987729567724904 0.8313121149746607 0.7987260637039444 1.0 14.93022177968971 -6.543086232806534 2.5866879990623177 0.8323752570650498 1.1964303670567986 0.8247498562833827 0.07477526427467109 0.10645384853223368 1.440707298212112 0.026054563648035003 0.02752479239986744 2.863609319840575e-07 6.543086232806534 0.36405510999174884 S(ph)PSLSLAPLSPR ddPTM_PC-9_Lapatinib_30min_R1 4 SPSLSLAPLSPR 12 0 G3V160;Q969H4-2;Q969H4 G3V160 CNKSR1 Connector enhancer of kinase suppressor of ras 1 1 S(0.959)PS(0.039)LS(0.003)LAPLSPR;S(0.999)PS(0.001)LSLAPLSPR;S(1)PSLSLAPLSPR;S(0.756)PS(0.243)LS(0.001)LAPLSPR 166.45 0.0008721 21644300.0 20857.100000000002 18266.3 21962.1 18912.6 10724.1 11637.0 7892.16 8385.9 9136.9 7514.200000000001 True False 20559.673929276294 18224.00550462812 20156.460914157633 20303.4956945841 10093.329522391816 11139.312637171943 8300.777428164538 8775.539528233066 8107.806106177562 8813.019457957871 2.332875131770142 2.0678503651971893 2.287123160264556 2.303806974606269 1.14527484825622 1.2639609716410536 0.9418766709597135 0.995747209012348 0.9199805066646568 1.0 13.105420675056132 -6.291074315367548 5.195945703851673 1.041728657419221 2.2413491907116385 0.9641853932094414 0.11368814304291013 0.03490900771109946 2.6869570108638205 0.03797469276136142 0.04457605827154098 5.115942853364606e-07 6.291074315367548 1.1996205332924175 up S(ph)PSLSPSPPSPLEK ddPTM_PC-9_AZD4547_30min_R2 1 SPSLSPSPPSPLEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.487)PS(0.094)LS(0.064)PS(0.141)PPS(0.214)PLEK 115.37 0.00015997 5927200.0 38694.0 69656.0 48393.0 69744.0 54398.0 57183.0 43008.0 56735.0 50256.0 64136.0 True False 50997.88711480169 92170.93980267874 47751.277200575496 53665.59833405851 46845.776677829424 53607.3379703411 46835.62868246415 47967.90939060106 52912.42956034256 61890.618161479055 0.824000286792142 1.4892554403349985 0.7715430645075713 0.8671039315529113 0.7569124056186339 0.8661625875261737 0.7567484390003203 0.7750433072981724 0.854934578651138 1.0 15.91743311115806 -5.30434942054431 24.999490269882617 0.8202612143320364 1.1566284926458443 0.3831333998242268 0.16478981731774303 357.82805893708814 208470.8406949104 0.03885462453513076 0.08088326937352418 4.96192938587225e-06 5.30434942054431 0.33636727831380797 S(ph)PSMAVPSPGWVASPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSMAVPSPGWVASPK 16 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 S(0.693)PS(0.305)MAVPS(0.001)PGWVASPK 63.128 0.03053 3366300.0 15667.0 15024.0 16505.0 14151.0 24036.0 23637.0 21781.0 19252.0 17763.0 18181.0 True False 18319.11366264508 16515.483429843054 16898.54179556106 13358.165348161008 19326.318343869705 22397.434109439626 19717.745999215833 18746.655399180134 18022.750270705557 21477.07137928318 0.8529614368333164 0.7689820990106648 0.7868177880090962 0.6219733180682314 0.8998581791049921 1.042853269605661 0.9180835529668911 0.8728683286522569 0.8391623770497095 1.0 14.3905096599007 -6.495681778913569 24.071072656770518 0.9306981013819663 0.7606146573311817 0.5519726857083509 0.07600638128524569 369.81836667793664 327313.350171948 0.02438902286920778 0.02756785279354185 3.1938772512089363e-07 6.495681778913569 -0.17008344405078457 S(ph)PSMAVPSPGWVASPK ddPTM_PC-9_Lapatinib_30min_R1 1 SPSMAVPSPGWVASPK 16 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 S(0.494)PS(0.394)MAVPS(0.111)PGWVAS(0.001)PK 80.632 0.007902 6303600.0 47099.0 45630.0 34926.0 36460.0 44719.0 43034.0 37872.0 41871.0 46363.0 44219.0 True False 46427.3596231012 45524.346538498845 32054.519098258774 39141.39002699451 42088.71634093673 41193.53613715367 39832.8268508808 43816.47951760057 41141.11071596607 51862.19523188616 0.8952062174675651 0.8777944384141563 0.6180710044173152 0.7547191138359183 0.8115490706235965 0.7942883241438046 0.7680513073690833 0.8448635720429574 0.7932774640953011 1.0 15.662395653676004 -9.795802794831152 0.6369235934287506 1.0167907574267847 0.7862646517623836 0.4137946556186842 0.07304492709409297 8.137307445659484 3.0327208132167174 0.41584107780997626 0.030029354063115504 1.600284523546377e-10 9.795802794831152 -0.23052610566440113 S(ph)PSMPCSVIRPILK ddPTM_PC-9_Lapatinib_30min_R1 1 SPSMPCSVIRPILK 14 1 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4;P30305-3 G8JLH2 CDC25B M-phase inducer phosphatase 2 1 S(0.779)PS(0.209)MPCS(0.012)VIRPILK 59.63399999999999 0.027764999999999998 10139000.0 26485.0 18612.0 25757.0 20172.0 21339.0 19444.0 17862.0 15835.0 20302.0 15867.0 True False 26107.31904324584 18568.905057517863 23639.358884895246 21655.516171819356 20083.881974088174 18612.425446177807 18786.80696056277 16570.751908509585 18015.374970462282 18609.589808551475 1.4028959967322336 0.9978137749702083 1.27027834187041 1.1636750941102538 1.0792221741964045 1.0001523750741153 1.0095228940473402 0.8904415454066051 0.9680694284934674 1.0 14.183758635500487 -6.5387516642069645 1.1884497818872741 0.9531472875719887 1.2112779398001516 0.5679204589349582 0.0975850899195318 0.34197478730397707 1.0157834767445169 0.04273407716626321 0.04772150244441931 2.892333287119957e-07 6.5387516642069645 0.2581306522281629 S(ph)PSPAHLPDDPK ddPTM_PC-9_AZD4547_30min_R2 2 SPSPAHLPDDPK 12 0 Q92615;H0Y4V9;A0A087X183;H0Y641 Q92615 LARP4B La-related protein 4B 1 S(0.791)PS(0.209)PAHLPDDPK;S(0.86)PS(0.14)PAHLPDDPK 123.26 0.0003632 98844000.0 163364.0 177424.0 246823.0 286873.0 256395.0 251258.0 244792.0 311586.0 275968.0 262367.0 True False 215310.35381771036 234772.8382845768 243549.9657487165 220738.86199366796 220798.97994985202 235546.79754038696 266578.01377505943 263437.54323397897 290555.1050801615 253181.6111882999 0.8504186098159263 0.9272902450643153 0.9619575632117294 0.8718597727443043 0.8720972226756082 0.9303471781969295 1.052912225828266 1.0405082027780106 1.1476153568833465 1.0 17.94981309874946 -7.234797304263554 3.077625588367809 1.0676351557574466 0.9003428253057474 0.7484894198458725 0.04515467071995937 0.13108058795448874 2.523957907806483 0.01969280874541789 0.01378260038851096 5.823749628285941e-08 7.234797304263554 -0.16729233045169922 S(ph)PSPAHLPDDPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPSPAHLPDDPK 12 0 Q92615;H0Y4V9;A0A087X183;H0Y641 Q92615 LARP4B La-related protein 4B 1 S(0.56)PS(0.44)PAHLPDDPK;S(0.904)PS(0.096)PAHLPDDPK;S(0.5)PS(0.5)PAHLPDDPK 166.24 0.00086232 176832000.0 385369.0 466093.0 538010.0 585074.0 671280.0 478150.0 581805.0 468842.0 466466.0 422796.0 True False 450604.36031530495 512363.63273867447 550838.1988142873 552294.2006155006 539747.5028238012 453074.9722650322 526692.2184965685 456535.39427916065 473287.1827830275 499445.5679487051 0.9022091479678195 1.0258648101394225 1.102899363141131 1.1058145993443338 1.0806933477067822 0.9071558570954515 1.0545537938393754 0.9140843839183863 0.9476251530810177 1.0 18.929967928971934 -6.750205215438644 24.999328062711147 0.9649309783529963 1.0492790349649859 0.2556669355676574 0.06687374711578811 311.8946734675681 694056.3935869982 0.02305874014409005 0.022859048893960312 1.7774393252614412e-07 6.750205215438644 0.08434805661198952 S(ph)PSPAHLPDDPK ddPTM_PC-9_Lapatinib_30min_R1 1 SPSPAHLPDDPK 12 0 Q92615;H0Y4V9;A0A087X183;H0Y641 Q92615 LARP4B La-related protein 4B 1 S(0.5)PS(0.5)PAHLPDDPK 80.507 0.008057600000000002 42391000.0 209500.0 257280.0 274590.0 247890.0 273090.0 300040.0 235350.0 270100.0 269550.0 217860.0 True False 206512.49158240505 256684.28396723556 252014.27014805283 266120.65753679804 257027.3831155975 287207.9886274012 247535.271423606 282649.83204852766 239190.440512664 255516.81071979753 0.8082148920090775 1.004569066294109 0.9862923282351641 1.0414996053963306 1.0059118317559799 1.1240277609067237 0.9687631538852284 1.1061887914626662 0.9361045163285276 1.0 17.96305868514672 -4.134199943904313 1.4501336447354272 1.0288809316529366 2.2379881015879496e-17 0.5629405746411241 0.055481941337345686 4.505876385821043 2.254542054214121 0.01438958813285406 10.660637266964656 7.341757847247086e-05 4.134199943904313 -1.0288809316529366 S(ph)PSPAHLPDDPKVAEK ddPTM_PC-9_AZD4547_30min_R2 1 SPSPAHLPDDPKVAEK 16 1 Q92615;H0Y4V9;A0A087X183;H0Y641 Q92615 LARP4B La-related protein 4B 1 S(0.5)PS(0.5)PAHLPDDPKVAEK 54.412 0.029376 14008000.0 104550.0 41554.0 142900.0 324230.0 268220.0 138440.0 100950.0 126180.0 95325.0 191820.0 True False 137794.72522490614 54985.517867240706 141005.05263079872 249483.78280356448 230982.28281421075 129783.32491499286 109934.3544339369 106681.78032794668 100363.68489015548 185104.44018546393 0.7444160987539997 0.29705131768934556 0.7617594288366061 1.347800098979777 1.2478484178055367 0.7011356658163224 0.5939044699510667 0.5763329081736651 0.542200310211883 1.0 17.497979976650804 -13.460699789080122 14.393330514977706 0.9948265441234152 0.7767549568378695 0.0 0.3104164395155822 0.0 0.0 0.0 0.07915602980188507 3.461785949629487e-14 13.460699789080122 -0.21807158728554565 S(ph)PSPAHLPDDPKVAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSPAHLPDDPKVAEK 16 1 Q92615;H0Y4V9;A0A087X183;H0Y641 Q92615 LARP4B La-related protein 4B 1 S(0.798)PS(0.202)PAHLPDDPKVAEK;S(0.5)PS(0.5)PAHLPDDPKVAEK 66.068 0.01153 20475700.0 100169.0 25899.0 51864.0 166302.0 163932.0 246566.0 129868.0 256244.0 184221.0 144706.0 True False 117125.6332720686 28470.08155947187 53100.63445531534 156984.63809835864 131810.70139570825 233635.64490536405 117565.96287710193 249517.8665129602 186914.88361310854 170940.05230793386 0.6851854301593217 0.16655009270843943 0.3106389271465712 0.9183607702164749 0.7710931383024416 1.3667694712324614 0.6877613601364584 1.4596805321170438 1.0934528279914024 1.0 17.383130943399465 -6.010107311893067 1.705600037094316 1.1036762742452484 0.35951866638102936 0.5770624602396714 0.25543947769839725 0.24205563799677296 1.4174864851497722 0.08236655728015553 0.13594984474907598 9.769957805846339e-07 6.010107311893067 -0.744157607864219 S(ph)PSPASGR ddPTM_PC-9_AZD4547_30min_R2 1 SPSPASGR 8 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.999)PS(0.001)PASGR 99.01299999999999 0.014038 0.0 14688.0 12367.0 12889.0 11093.0 8665.7 10235.0 9319.7 9561.0 12876.0 15876.0 True False 19358.47847062095 16364.390900133925 12718.083438477 8535.680235141546 7462.617135870192 9595.003832020722 10149.135245348805 8083.567139923092 13556.599073125011 15320.186072278319 1.2635929080293529 1.06815875622719 0.8301520215534595 0.5571525172652276 0.48711008473805045 0.6262981263251599 0.6624681448036416 0.5276415770530493 0.8848847533030624 1.0 13.903146199261599 -5.2454821553016 2.0312879318976513 0.6487899638937791 1.24642741658123 0.6120879470868691 0.15435870967874 0.22231381977130812 1.6470494734604497 0.041722159355949064 0.1695220709159342 5.682217387072011e-06 5.2454821553016 0.5976374526874508 S(ph)PSPASGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSPASGR 8 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.999)PS(0.001)PASGR;S(1)PSPASGR 112.11 0.0037351999999999997 5980900.0 11618.8 24021.0 21706.0 14443.0 40666.0 34373.0 18247.2 23378.0 34777.0 35414.0 True False 13585.633358239656 26405.646130741494 22223.553360463404 13633.805534837782 32697.789223323576 32570.41936979178 16518.69311771227 22764.35227103849 35285.54783337991 41834.27786293024 0.3247488435859441 0.6311964130768418 0.5312283250897444 0.32590034372073695 0.7816028121832934 0.7785581832321466 0.39486024288110505 0.5441554972127343 0.8434601870980729 1.0 15.352397911264983 -14.522878743529807 0.10957601095723363 2.4390460856852636 0.3161829282113921 0.47136680942945786 0.15987450802794603 165.40560065574658 1.2017166161681627 52.854243131703576 2.115385411586156 3.000000012092237e-15 14.522878743529807 -2.1228631574738714 S(ph)PSPASGR ddPTM_PC-9_Lapatinib_30min_R1 2 SPSPASGR 8 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.999)PS(0.001)PASGR;S(0.999)PS(0.001)PASGR 72.243 0.033212 7515000.0 8553.7 19486.1 15333.2 15549.300000000001 25737.6 13618.9 35372.0 33215.0 23027.0 23716.6 True False 8431.722669443536 19440.981132672412 14072.563483863634 16692.84739294422 24223.764970068496 13036.451394206484 37203.38908347478 34758.290157318974 20433.456774940154 27815.982709616932 0.30312510463735665 0.6989140500849895 0.5059164592807383 0.6001171185360614 0.8708577806849699 0.4686676552218067 1.3374824636561304 1.24957980166208 0.7345940996675847 1.0 14.763626454950318 -7.2535882779379 24.995395060144737 1.1012124123177038 0.5917545315023794 0.5937332114544205 0.20439341476574213 414.03550395897713 1318159.0137245236 0.07839861358160044 0.059601413923218924 5.5771422546253406e-08 7.2535882779379 -0.5094578808153244 S(ph)PSPASGRR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSPASGRR 9 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.704)PS(0.296)PASGRR 60.691 0.031617 2059700.0 1339.9 1233.1 836.7 1082.1 2499.7 1155.4 1104.0 970.16 1932.6 1017.3 True False 1320.792780292434 1230.2448327114387 767.9097557554007 1161.6812437797805 2352.672560599286 1105.9862353689496 1161.1597180865124 1015.2371753432053 1714.9302368197918 1193.1389495329558 1.1069899116187993 1.0310993813361031 0.6436046330194757 0.973634499346879 1.9718345139266635 0.9269551009141714 0.9731973954425329 0.8508960131932759 1.4373265054259496 1.0 10.220546349597218 -4.411288452727212 17.15013424172748 1.085407518772037 2.880656966201324 7.213762314983718e-05 0.3493165521125481 53160420.10679507 46536963.16478392 0.08978691652050205 3702129087.039181 3.8789264717924126e-05 4.411288452727212 1.795249447429287 S(ph)PSPAVPLR ddPTM_PC-9_AZD4547_30min_R2 2 SPSPAVPLR 9 0 Q6P4R8-3;Q6P4R8;Q6P4R8-2;E9PQ59 Q6P4R8-3 NFRKB Nuclear factor related to kappa-B-binding protein 1 S(0.989)PS(0.011)PAVPLR;S(0.937)PS(0.063)PAVPLR 114.97 0.0020071999999999998 31308000.0 108350.0 118815.0 121596.0 201853.0 153981.0 172010.0 124769.0 172612.0 108617.0 136798.0 True False 142803.04617999605 157219.6251960388 119983.55759058507 155318.90944776204 132603.3960555324 161254.18750814715 135873.19929041996 145938.781629161 114358.27287399958 132008.74365807025 1.0817696027006003 1.1909788763937479 0.9089061395915343 1.1765804684125312 1.0045046440181449 1.2215417179170238 1.029274239912164 1.105523600824294 0.8662931689601636 1.0 17.01027396473544 -8.249536432793596 24.661803247097684 0.9331465850547938 1.089634137477293 0.30866756537837337 0.09382754341292546 618.305801045105 1281079.75960823 0.059658282508727685 0.022142212044940893 5.629418904391512e-09 8.249536432793596 0.15648755242249934 S(ph)PSPAVPLR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSPAVPLR 9 0 Q6P4R8-3;Q6P4R8;Q6P4R8-2;E9PQ59 Q6P4R8-3 NFRKB Nuclear factor related to kappa-B-binding protein 1 S(0.89)PS(0.11)PAVPLR 111.61 0.0022237 14917000.0 45917.0 52773.0 53540.0 43471.0 49611.0 65363.0 42749.0 57720.0 63950.0 39092.0 True False 45262.21515985346 52650.80736086349 49138.14787037666 46668.00235500494 46692.97851897879 62567.57685859499 44962.33404753656 60401.88191721964 56747.27757664584 45849.00011318421 0.987201793891204 1.1483523573226926 1.0717387020234415 1.0178630338676724 1.0184077821481627 1.364644304219041 0.9806611689795024 1.3174089242537406 1.23769934865663 1.0 15.484602651047423 S(ph)PSPEPIYNSEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSPEPIYNSEGK 13 0 Q15637-6;Q15637-4;Q15637-7;Q15637-3;Q15637-2;Q15637;Q15637-5 Q15637-6;Q15637-5 SF1 Splicing factor 1 1 S(0.513)PS(0.487)PEPIYNSEGK 162.88 0.0003366 10963000.0 22975.0 38593.0 40528.0 28834.0 32804.0 18526.0 25728.0 19319.0 20254.0 14782.0 True False 26864.21372306572 42424.257987748504 41494.341223295916 27218.52446108928 26376.291685484368 17554.463946840915 23290.857585410427 18811.896720172503 20550.17643319655 17461.85958575239 1.5384509073125847 2.429538376448956 2.3762842107121447 1.558741457484724 1.510508749423544 1.0053032359259195 1.3338131297547529 1.0773134801474205 1.1768607078918445 1.0 14.091919585268576 -6.144424201575894 1.8800789965617886 1.1525614401024824 2.1347362221117674 0.7041971902838104 0.26878648958315005 0.18098454187614813 1.2636385690992138 0.08927042198814808 0.12830971592435836 7.170935206560071e-07 6.144424201575894 0.982174782009285 S(ph)PSPEPIYNSEGK ddPTM_PC-9_Lapatinib_30min_R1 2 SPSPEPIYNSEGK 13 0 Q15637-6;Q15637-4;Q15637-7;Q15637-3;Q15637-2;Q15637;Q15637-5 Q15637-6;Q15637-5 SF1 Splicing factor 1 1 S(0.714)PS(0.286)PEPIYNSEGK;S(0.753)PS(0.247)PEPIYNSEGK 153.32 0.00014488 43051000.0 33420.0 50060.0 42659.0 40268.0 53505.0 53076.0 46839.0 52128.0 46943.0 38782.0 True False 32943.42467152258 49944.08914567721 39151.74168850201 43229.44305011013 50357.94109487733 50806.06320619903 49264.094235012824 54550.05718262002 41655.785008295315 45485.41702623324 0.7242634414569137 1.0980242110756613 0.8607537151065724 0.9504022580507067 1.107122774445135 1.116974769669522 1.0830744765206894 1.1992867329579244 0.9158052785197237 1.0 15.473116459889967 -6.163011367363473 4.4603568579161825 1.0831373978309675 0.9138372881136 0.3381025396527648 0.11096886101905909 0.25787607678533525 8.70676828380892 0.031503861861944746 0.04121366361484483 6.870504566992189e-07 6.163011367363473 -0.16930010971736753 S(ph)PSPEPR ddPTM_PC-9_AZD4547_30min_R2 1 SPSPEPR 7 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(0.934)PS(0.066)PEPR 99.13600000000001 0.011939 4423900.0 29352.0 28428.0 29374.0 41072.0 43297.0 30484.0 28178.0 47049.0 32607.0 38298.0 True False 38685.32544047294 37616.795060160686 28984.481567369363 31603.484956074393 37285.958910621375 28577.830660998527 30685.787411980913 39778.658128463736 34330.53945149016 36957.19867700395 1.0467602206155384 1.0178475752158986 0.7842716062081976 0.8551374586661834 1.0088957022010976 0.7732683126435295 0.8303060976067613 1.0763439749889754 0.928926993399308 1.0 15.173567785438706 -7.759707273920689 24.999998945291313 1.0019766044820664 0.8995723722769973 0.1796605315869957 0.09720845011094797 82.65496015322867 1193043.3197659983 0.050756314546053796 0.0273534155611589 1.7389725477592116e-08 7.759707273920689 -0.10240423220506911 S(ph)PSPFHAVAECR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSPFHAVAECR 12 0 E5RJ35;E7EPX3;B9ZVU2;F8WAN0;C9JBE1;E5RIA4;E7ETB3;Q9ULA0-2;Q9ULA0 E5RJ35 DNPEP Aspartyl aminopeptidase 1 S(1)PSPFHAVAECR;S(1)PSPFHAVAECR 72.531 0.024809 29569000.0 58454.0 65061.0 100340.0 96992.0 121460.0 87768.0 96859.0 94754.0 83880.0 55875.0 True False 68349.10768087405 71519.82610683034 102732.48614156901 91557.85269230677 97660.78490790531 83165.29157326641 87683.8143215667 92266.80790016156 85106.58631463053 66004.69519374346 1.0355188745323198 1.0835566454310306 1.5564420961269274 1.3871415120326995 1.4796036042775713 1.2599905405085423 1.3284481363664895 1.3978824935003633 1.289402004884915 1.0 16.010281032684205 -5.126200086908031 7.2639574801529925 1.3549890679526704 1.0480574105356535 0.37933404906916823 0.14119461509633047 0.21785675955223122 11.688894090670491 0.033830680688029593 0.09121087311331744 7.478248853959665e-06 5.126200086908031 -0.3069316574170169 S(ph)PSPFTHTHLAQGYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSPFTHTHLAQGYR 15 0 P38398-8;P38398-4;P38398;P38398-7;Q5YLB2 P38398-8 BRCA1 Breast cancer type 1 susceptibility protein 1 S(0.599)PS(0.401)PFT(0.001)HTHLAQGYR 64.454 0.020353 2960200.0 23569.0 24934.0 23468.0 28103.0 28783.0 28705.0 31162.0 24183.0 21902.0 20173.0 True False 27558.76619103094 27409.282736934703 24027.566122885615 26528.48002115529 23143.177770494345 27199.659267735515 28210.109766657344 23548.22187400648 22222.27531548685 23830.205210619868 1.1564636538987692 1.150190797547972 1.0082819644447625 1.1132291890349708 0.9711698898917014 1.1413942526862528 1.1837963423867446 0.9881669782479372 0.9325255539798522 1.0 14.540503754706206 -1.5228787505484593 0.12505648722573137 0.9548028917720508 1.5574060594363308 0.25626378376230563 0.07596689993999986 145.56506957139223 1.246282330006702 0.49603413325283935 15.364361819446856 0.029999999636091044 1.5228787505484593 0.60260316766428 S(ph)PSPGLFR ddPTM_PC-9_AZD4547_30min_R2 3 SPSPGLFR 8 0 E7ESG2;Q9HAW4-2;Q9HAW4-3;Q9HAW4 E7ESG2 CLSPN Claspin 1 S(0.925)PS(0.075)PGLFR;S(0.743)PS(0.257)PGLFR;S(0.939)PS(0.061)PGLFR 106.68 0.0038220999999999997 52557700.0 277604.0 253021.0 281015.0 369932.0 369968.0 336181.0 275936.0 409766.0 278283.0 220431.0 True False 365876.2974780955 334805.09015466867 277288.55748806073 284649.89279242617 318604.32931253396 315159.5489255063 300493.76944113773 346446.0801859356 292992.47125399555 212713.77778397477 1.72004042845625 1.5739699310624151 1.3035759149069601 1.338182677952847 1.4978076767368507 1.4816132373219948 1.4126671651062936 1.6286960054734914 1.3774024151437394 1.0 17.6985539562397 -8.548796452487574 21.205763190769662 0.9999999953052539 1.4838617102737184 0.6045971636193145 0.11994599151030848 651.5267964742973 533076.9622522077 0.12145764162832225 0.03136022820638023 2.8262042654219253e-09 8.548796452487574 0.48386171496846453 S(ph)PSPGLFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPSPGLFR 8 0 E7ESG2;Q9HAW4-2;Q9HAW4-3;Q9HAW4 E7ESG2 CLSPN Claspin 1 S(0.877)PS(0.123)PGLFR;S(0.883)PS(0.117)PGLFR;S(0.993)PS(0.007)PGLFR 105.1 0.0038475000000000002 38584800.0 172804.0 163911.0 195348.0 205773.0 240186.0 175563.0 238542.0 208546.0 200597.0 181935.0 True False 202056.30416542542 180183.00082993892 200005.8371814151 194244.2059350668 193123.2774896273 166356.16721900203 215945.57486547666 203071.88847275195 203530.35163276034 214918.37530333223 0.9401536926763312 0.8383787592644492 0.9306130148207671 0.9038045521278194 0.8985889513498151 0.7740434803874248 1.0047794869130882 0.9448791346302504 0.9470123312885693 1.0 17.713429311440166 -7.305578624445657 24.999997163895642 0.969574340972072 0.883096790779238 0.47044438871314 0.04833060140406723 447.2918886795032 253339.77424765538 0.019879583333464425 0.013402900744555036 4.947905261934985e-08 7.305578624445657 -0.08647755019283399 S(ph)PSPGLFR ddPTM_PC-9_Lapatinib_30min_R1 4 SPSPGLFR 8 0 E7ESG2;Q9HAW4-2;Q9HAW4-3;Q9HAW4 E7ESG2 CLSPN Claspin 1 S(0.995)PS(0.005)PGLFR;S(0.834)PS(0.166)PGLFR;S(0.998)PS(0.002)PGLFR;S(0.983)PS(0.017)PGLFR 106.68 0.0038220999999999997 63183300.0 375276.0 329743.0 346486.0 353813.0 364427.0 289901.0 272247.0 276192.0 333279.0 253884.0 True False 369924.4954228107 328979.50034284894 317999.25855463836 379833.5883055675 342992.12035104836 277502.61002223776 286342.6175451981 289024.8886084677 295741.6094365433 297767.51112083416 1.2423265856989187 1.1048199956554325 1.0679447779834992 1.2756045374991596 1.151878924131055 0.9319438812437368 0.9616314972287229 0.9706394345056043 0.9931963642485203 1.0 18.18382682707476 -6.741350639487079 11.560296846983768 0.9690325450913388 1.16541710620469 0.7382275311612994 0.05864106920317831 0.3086800666702068 175.4364146394493 0.019923223397373298 0.01965456152043069 1.814050448289185e-07 6.741350639487079 0.19638456111335123 S(ph)PSPGNSPSGR ddPTM_PC-9_AZD4547_30min_R2 1 SPSPGNSPSGR 11 0 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 S(0.929)PS(0.067)PGNS(0.004)PSGR 77.74 0.019166 1464800.0 6916.1 4325.9 7167.1 9250.9 7879.7 6840.2 6377.1 8651.8 6276.5 8163.1 True False 9115.275936183392 5724.162577414844 7072.059571100051 7118.247929980251 6785.739668522598 6412.481212680819 6944.649545920348 7314.86310858557 6608.262976271293 7877.312353654264 1.1571555788256689 0.7266644155299263 0.8977756947544857 0.903639161481024 0.8614282846578645 0.8140442989677927 0.8816013932339173 0.9285988393226815 0.8388981773974898 1.0 12.94348776771299 -10.756028648670933 3.778567448651423 1.0001469969949603 0.883622635889796 0.08779336020118411 0.10460309742037215 139216477.76987702 246359263.48918295 241595.4827104511 0.024108426249289914 1.7537648091719086e-11 10.756028648670933 -0.1165243611051644 S(ph)PSPGNSPSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSPGNSPSGR 11 0 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 S(0.994)PS(0.006)PGNSPSGR 85.973 0.031498000000000005 0.0 995.83 948.79 2541.6 2259.6 2345.7 2740.7 2258.9 1228.7 2789.2 990.14 True False 1164.4043504609594 1042.9796008653348 2602.2013830716774 2133.00193772204 1886.0769237483432 2596.9728672733936 2044.9206389802412 1196.4479269152614 2829.986773352021 1169.6445440560722 0.9955198409450611 0.8917064642976994 2.224779653182334 1.8236326143370487 1.612521456482702 2.220309478183567 1.748326574404308 1.022915836264444 2.4195271868992303 1.0 10.19185444486218 -5.24293720682714 24.682765606372207 1.7729908684110194 0.9436129103148319 0.3449998947890791 0.44907191250105344 731.763011661261 976201.7167616993 0.10842740568352166 0.28569808640918887 5.7156127081225164e-06 5.24293720682714 -0.8293779580961875 S(ph)PSPGNSPSGR ddPTM_PC-9_Lapatinib_30min_R1 4 SPSPGNSPSGR 11 0 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 S(0.964)PS(0.036)PGNSPSGR;S(0.878)PS(0.11)PGNS(0.011)PSGR;S(0.992)PS(0.006)PGNS(0.002)PSGR;S(0.541)PS(0.458)PGNSPSGR 118.61 0.001047 10054900.0 19285.2 19242.800000000003 25396.6 18590.690000000002 19686.6 24313.7 21736.920000000002 22393.699999999997 22105.47 17786.9 True False 19010.189511527467 19198.244478874116 23308.589581711 19957.91135932384 18528.67289334477 23273.859729002947 22862.351358033608 23434.193054221098 19615.71918768127 20861.34196544553 0.9112639801895637 0.9202784993733315 1.117310172102977 0.9566935527149634 0.8881822139743185 1.115645377346936 1.0959194952991291 1.1233310442366176 0.940290381135236 1.0 14.348544345874103 -6.770975825815422 24.998186206671825 1.065300585597266 0.9653037438107313 0.2695460983832839 0.07797870532888429 278.1444155956534 729103.9080046369 0.028002708540869177 0.02500832491715505 1.694432115195529e-07 6.770975825815422 -0.09999684178653467 S(ph)PSPISISSSETSSIMQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSPISISSSETSSIMQK 18 0 Q5VT06 Q5VT06 CEP350 Centrosome-associated protein 350 1 S(0.77)PS(0.226)PIS(0.003)ISSSETSSIMQK 114.28 0.00012593 7085200.0 36994.0 33414.0 41771.0 49785.0 55570.0 42312.0 48510.0 42130.0 39735.0 32511.0 True False 43256.35353519451 36731.12109456708 42766.979057399636 46995.70785514774 44681.4574125828 40093.08423398103 43914.781618013825 41024.13214042483 40316.049203765426 38404.98694306562 1.1263212665407467 0.9564154037864927 1.1135787943581534 1.2236876404831913 1.1634285276238183 1.0439551585688072 1.1434656046912952 1.0681980494158747 1.0497607840235152 1.0 15.22900603869621 -10.928229231805481 7.611739014658534 0.9999970433256417 1.0993871431589186 0.15089963096890013 0.07026438042190065 3.725205101233957e-06 2.910325919174517e-07 0.07185086327644968 0.017425875512834636 1.179697796430719e-11 10.928229231805481 0.09939009983327696 S(ph)PSPLVSLQAVK ddPTM_PC-9_AZD4547_30min_R2 2 SPSPLVSLQAVK 12 0 Q9UPZ3;Q9UPZ3-2 Q9UPZ3 HPS5 Hermansky-Pudlak syndrome 5 protein 1 S(0.644)PS(0.356)PLVSLQAVK;S(0.553)PS(0.447)PLVSLQAVK 159.66 9.802299999999999e-05 48575000.0 86218.0 87843.0 138735.0 187488.0 153204.0 141319.0 138213.0 165428.0 140585.0 153891.0 True False 113633.53055419377 116236.5318865097 136895.28325216137 144265.53826072463 131934.26909353613 132482.3005898719 150513.6892459404 139864.90375726356 148016.03609003426 148503.3229307746 0.7651918375399889 0.7827200738174311 0.9218331317473323 0.971463368048502 0.8884263765265227 0.8921167417353284 1.013537517380018 0.9418301287605674 0.9967186805579598 1.0 17.18013568776665 -3.3414805051919525 0.441413197039248 0.9771259331385871 1.612577896143201e-15 0.7442899913746228 0.04190744399542223 9.06389196281365 0.5056347382871174 0.029235194865761278 6.078851348184975 0.0004555326338626662 3.3414805051919525 -0.9771259331385854 S(ph)PSPPDGS(ph)PAATPEIR ddPTM_PC-9_AZD4547_30min_R2 2 SPSPPDGSPAATPEIR 16 0 O00499-6;O00499-11;O00499-2;O00499;O00499-7;O00499-8;O00499-4;O00499-3;O00499-5;O00499-9;O00499-10 O00499-6;O00499-9 BIN1 Myc box-dependent-interacting protein 1 2 S(0.879)PS(0.121)PPDGS(0.999)PAAT(0.001)PEIR;S(0.997)PS(0.003)PPDGS(1)PAATPEIR 197.75 6.9952e-11 15262500.0 38586.0 42694.0 59489.0 74501.0 61711.0 69735.0 52157.0 63599.0 54224.0 51108.0 True False 50855.54536134125 56494.000573325604 58700.136990577914 57325.94547897589 53143.49285939797 65374.459426083515 56798.87195850267 53771.23590962964 57090.169939509986 49318.72447606448 1.0311610022684714 1.1454878684209169 1.1902200962043625 1.1623566117732322 1.0775520539909693 1.325550490621696 1.1516695243419866 1.0902803444506368 1.157575962192963 1.0 15.589847867533258 -10.634985815286404 4.110915372222912 0.9999665166046452 1.1511376133276632 0.2606258439459509 0.07460538986297696 26621706.257172294 0.6596882288587862 8525.271044775574 0.018093584804937644 2.317470340813267e-11 10.634985815286404 0.15117109672301798 S(ph)PSPPDGS(ph)PAATPEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSPPDGSPAATPEIR 16 0 O00499-6;O00499-11;O00499-2;O00499;O00499-7;O00499-8;O00499-4;O00499-3;O00499-5;O00499-9;O00499-10 O00499-6;O00499-9 BIN1 Myc box-dependent-interacting protein 1 2 S(0.974)PS(0.027)PPDGS(0.999)PAATPEIR 98.572 0.028408999999999997 0.0 4584.6 7704.1 7033.3 4940.9 7791.5 7967.6 8276.4 7570.8 5691.2 2719.7 True False 5360.68223002251 8468.912133376856 7201.000545938788 4664.0773916139315 6264.811506750744 7549.765029841822 7492.399476052975 7372.074521925668 5774.423033307405 3212.7600808666475 1.668559772622815 2.636023830043466 2.241375130631076 1.4517353534708353 1.9499780092700856 2.349931161932658 2.3320756257752953 2.294623419230557 1.7973402582086815 1.0 11.649597533424243 -8.616637495364111 4.091151522168959 1.0002317840629449 2.122369030149582 0.5108825073401337 0.3301578126824937 0.4013831161312183 15.372475574050252 0.3307328630991745 0.08655201784819681 2.4174778559033063e-09 8.616637495364111 1.122137246086637 S(ph)PSPPDGSPAATPEIR ddPTM_PC-9_AZD4547_30min_R2 2 SPSPPDGSPAATPEIR 16 0 O00499-6;O00499-11;O00499-2;O00499;O00499-7;O00499-8;O00499-4;O00499-3;O00499-5;O00499-9;O00499-10 O00499-6;O00499-9 BIN1 Myc box-dependent-interacting protein 1 1 S(0.81)PS(0.19)PPDGSPAATPEIR;S(0.978)PS(0.022)PPDGSPAATPEIR 152.11 3.1293e-05 46435000.0 9347.3 12215.5 16852.7 21587.0 20690.5 21348.6 17659.9 18137.1 15571.2 16169.7 True False 12319.546964081928 16163.9214878779 16629.222186641444 16610.45066582533 17817.981219026977 20013.66866714974 19231.596888240547 15334.427944095725 16394.261842765165 15603.603724673638 0.7895321607406177 1.035909509949823 1.0657295891426681 1.0645265644345727 1.1419144918972655 1.282631180610064 1.2325099526739483 0.9827491273600937 1.0506715071750559 1.0 13.929591644232731 -4.178640853499941 1.1274430355703224 1.1196294638742843 2.7613988764539437e-17 0.5171604493627142 0.09040274046460667 4.715016953404077 1.9230371894297102 0.030119128511417046 8.709777462612399 6.627643603205645e-05 4.178640853499941 -1.1196294638742843 S(ph)PSPPDGSPAATPEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSPPDGSPAATPEIR 16 0 O00499-6;O00499-11;O00499-2;O00499;O00499-7;O00499-8;O00499-4;O00499-3;O00499-5;O00499-9;O00499-10 O00499-6;O00499-9 BIN1 Myc box-dependent-interacting protein 1 1 S(0.573)PS(0.427)PPDGSPAATPEIR;S(0.919)PS(0.081)PPDGSPAATPEIR 249.36 2.7484999999999998e-47 225037000.0 116763.0 145254.0 140194.0 151780.0 140419.0 123124.0 117423.0 99797.0 115921.0 91981.0 True False 136528.66972562883 159673.85716975702 143536.7566487057 143276.25867739934 112904.90495622574 116667.16069258544 106299.84337109933 97177.43449366186 117616.12532401395 108656.42717880449 1.2565172007814864 1.4695297951127961 1.3210148757468558 1.318617429244426 1.039100105605626 1.0737253535918176 0.9783116022780026 0.8943551432419837 1.0824589799042943 1.0 16.729413988898422 -6.270023746137372 2.0747297440331613 0.9950044452423352 1.3650145329192844 0.8405925452513744 0.07037517900324972 0.11548065734709634 0.9760322749873904 0.023394437588560527 0.030111862662199635 5.370024336159196e-07 6.270023746137372 0.3700100876769492 S(ph)PSPPDGSPAATPEIR ddPTM_PC-9_Lapatinib_30min_R1 2 SPSPPDGSPAATPEIR 16 0 O00499-6;O00499-11;O00499-2;O00499;O00499-7;O00499-8;O00499-4;O00499-3;O00499-5;O00499-9;O00499-10 O00499-6;O00499-9 BIN1 Myc box-dependent-interacting protein 1 1 S(0.872)PS(0.124)PPDGS(0.004)PAATPEIR;S(0.94)PS(0.06)PPDGSPAATPEIR 145.86 2.9713e-05 47654000.0 16349.5 15904.300000000001 16023.7 15661.1 16303.8 14191.6 13994.2 13214.099999999999 16849.0 14564.9 True False 16116.35313186891 15867.474570507276 14706.293239270715 16812.869537898077 15344.842538504094 13584.65835023539 14718.751201853522 13828.075326443734 14951.288192164264 17082.42355849066 0.9434465242409017 0.9288772471995342 0.8609020370508896 0.9842203877178421 0.8982825233177808 0.7952418638796286 0.8616313224792803 0.8094914213487358 0.8752439688063387 1.0 14.06022505051343 -6.53033984341744 24.85955703538085 0.8549707048241039 0.9265388024623892 0.17361188893707968 0.0592042691165876 231.28876688005192 770621.6916332475 0.01832713676514471 0.018363854858820975 2.948900754511537e-07 6.53033984341744 0.07156809763828531 S(ph)PSPPLPLSCSNSTR ddPTM_PC-9_AZD4547_30min_R2 1 SPSPPLPLSCSNSTR 15 0 Q96HJ3-2;Q96HJ3 Q96HJ3-2 CCDC34 Coiled-coil domain-containing protein 34 1 S(0.646)PS(0.354)PPLPLSCSNSTR 98.59200000000001 0.0022262 16205000.0 6377.1 4670.3 8364.5 8557.2 8881.8 6381.5 9537.7 9486.4 5753.2 6094.1 True False 8404.885148079857 6179.883142305774 8253.581264732786 6584.46974742209 7648.715381027712 5982.463796193478 10386.536823026847 8020.494855785633 6057.302406609411 5880.747413899676 1.429220566116163 1.050866957437938 1.4034918835698849 1.1196654581455248 1.3006366100590012 1.0172965058919867 1.7661933240794074 1.3638563759478042 1.0300225431026728 1.0 12.521783810778313 S(ph)PSPPLPLSCSNSTR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSPPLPLSCSNSTR 15 0 Q96HJ3-2;Q96HJ3 Q96HJ3-2 CCDC34 Coiled-coil domain-containing protein 34 1 S(0.988)PS(0.012)PPLPLSCSNSTR 103.11 0.0013494000000000002 15040000.0 15027.0 16330.0 18184.0 19076.0 17672.0 13666.0 14788.0 22887.0 18581.0 14309.0 True False 14812.712224385692 16292.188888312206 16688.98171226988 20478.91267567053 16632.567704488785 13081.537037001948 15553.650281760294 23950.4135731013 16488.21211339572 16782.29158445599 0.8826394267935046 0.9707964378000842 0.9944399802782277 1.2202691493358633 0.9910784603393566 0.7794845519856337 0.9267894198767419 1.4271241476512382 0.9824767988578715 1.0 14.03465210556573 S(ph)PSPPLPTHIPPEPPR ddPTM_PC-9_AZD4547_30min_R2 1 SPSPPLPTHIPPEPPR 16 0 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 S(0.5)PS(0.5)PPLPTHIPPEPPR 79.462 0.0050423 4406600.0 11510.0 10043.0 13049.0 15231.0 16901.0 11385.0 10131.0 9979.5 8650.2 11792.0 True False 15169.940577127407 13289.203348430918 12875.961733934859 11719.728266604236 14554.587882495583 10673.094150225297 11032.639373652448 8437.397581096378 9107.431912266698 11379.165669205464 1.333132939454482 1.1678539301343014 1.1315382962373117 1.0299286087661426 1.279055802999996 0.937950501864038 0.9695473020055598 0.7414776993650634 0.8003602528534601 1.0 13.474107161356836 -7.03341677140961 1.950859619696523 0.8446151646488078 1.1761679551878403 0.6433261256080998 0.10872291033464866 0.21083728654268308 1.6036373368989134 0.049173437189212764 0.03708294890294678 9.25940816260813e-08 7.03341677140961 0.3315527905390325 S(ph)PSPPLPTHIPPEPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSPPLPTHIPPEPPR 16 0 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 S(0.558)PS(0.442)PPLPTHIPPEPPR 105.9 0.0019581 0.0 20138.0 25417.0 14222.0 18846.0 15272.0 13236.0 19163.0 16330.0 17367.0 17233.0 True False 23546.965656369863 27940.23178489889 14561.106417235347 17790.119719556384 12279.561230969306 12541.880859353678 17347.74191189445 15901.35480306521 17620.95951986395 20357.206483647056 1.1566894345393186 1.3724983242343824 0.7152801848786219 0.8738978864240133 0.6032046312854112 0.6160904674926087 0.8521671146691905 0.7811167419183358 0.8655882885512247 1.0 14.313251980810906 -5.264988324991446 24.99945944439795 0.7731611611125531 1.2645938991545653 0.6973462543539799 0.12515796765252657 141.9237166172802 999745.198981578 0.03211494077348552 0.07134968637317414 5.432649357247763e-06 5.264988324991446 0.49143273804201226 S(ph)PSPPLPTHIPPEPPR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSPPLPTHIPPEPPR 16 0 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 S(0.5)PS(0.5)PPLPTHIPPEPPR 107.69 0.0004981 3665600.0 15759.0 11556.0 12021.0 10351.0 12475.0 14052.0 8276.2 9964.9 12014.0 8312.9 True False 15534.273770153337 11529.242791998518 11032.679782401905 11112.247069923767 11741.24502679366 13451.028716811907 8704.701140242392 10427.90563265596 10660.856806971433 9749.773688757015 1.5932958308628986 1.1825138880191142 1.13158316639947 1.1397441032644575 1.2042582116888638 1.3796247119379812 0.8928105839297837 1.0695536086833415 1.0934465914080689 1.0 13.251153016150258 -4.746843855337875 3.3400857921013576 1.123117059965616 1.6780847212207664 0.5846550620612795 0.12031285274952332 0.27925938439036735 4.602042938657949 0.031576399811157424 0.42073841417822466 1.7912497577130476e-05 4.746843855337875 0.5549676612551504 S(ph)PSPPTQHTGQPPGQPSAPSQLSAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSPPTQHTGQPPGQPSAPSQLSAPR 26 0 Q68EM7-6;Q68EM7-5;Q68EM7;Q68EM7-7;Q68EM7-3;Q68EM7-2;I3L460 Q68EM7-6 ARHGAP17 Rho GTPase-activating protein 17 1 S(0.702)PS(0.212)PPT(0.086)QHTGQPPGQPSAPSQLSAPR 126.55 7.4983e-12 79411000.0 4152.3 1274.3 3589.0 7893.2 10080.0 7138.0 5131.7 7986.3 3529.5 5439.1 True False 4855.202378336709 1400.8040824446894 3674.575371358297 7450.969594099669 8104.896359885453 6763.67071426916 4645.588225709372 7776.668087184309 3581.1122603420185 6425.1657741080935 0.7556540249750493 0.21801835652079207 0.571903589813351 1.15965406279871 1.2614299217844742 1.052684234471453 0.723030095881728 1.21034512736192 0.5573571774245979 1.0 12.649517962065623 -5.657629784938394 5.630694752812023 1.0046686395085822 0.4674837674888567 0.4627920254544263 0.23704619233428892 0.1668197711343654 7.71527712011342 0.06352654008537192 0.11125347131018712 2.1997342409209323e-06 5.657629784938394 -0.5371848720197254 S(ph)PSPSFR ddPTM_PC-9_AZD4547_30min_R2 3 SPSPSFR 7 0 P49585;C9JEJ2 P49585 PCYT1A Choline-phosphate cytidylyltransferase A 1 S(0.999)PS(0.001)PSFR;S(0.997)PS(0.003)PSFR;S(0.992)PS(0.008)PSFR 93.598 0.014112999999999999 8218500.0 44144.0 46706.0 59950.0 76463.0 67157.0 62032.0 48103.0 68897.0 51947.0 60840.0 True False 58180.87374775952 61802.80111438951 59155.02382936587 58835.63669157372 57833.40976420073 58153.12923379677 52384.073812141345 58250.5517455581 54692.81236809762 58710.01011825476 0.9909872887190883 1.052679108552446 1.0075798609166435 1.002139781155989 0.985068979680154 0.9905147200053908 0.8922511460418487 0.9921741050330053 0.9315755909074853 1.0 15.841318884873624 -6.4978449244509715 1.3598151464039767 0.9545425394847757 1.0193044568821459 0.3685302309617523 0.03293806064437933 0.41187250928807817 1.5687589256885055 0.013291962974440625 0.015154550051594912 3.178008654392129e-07 6.4978449244509715 0.06476191739737014 S(ph)PSPSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPSPSFR 7 0 P49585;C9JEJ2 P49585 PCYT1A Choline-phosphate cytidylyltransferase A 1 S(1)PSPSFR;S(0.997)PS(0.003)PSFR;S(0.999)PS(0.001)PSFR 125.16 5.2245e-05 84067000.0 52398.3 58204.0 74634.0 70398.0 77229.0 73448.0 57131.0 48350.0 60042.0 39307.1 True False 61268.297276401114 63982.108463164615 76413.55761102134 66453.82829339535 62096.53184301516 69596.25758218566 51719.13808737886 47080.86373105961 60920.00066169581 46433.16607516758 1.3194942851240838 1.3779398191281682 1.6456676136906212 1.4311715937228497 1.3373314182903486 1.4988479887311772 1.113840439044242 1.0139490306313275 1.311993254198442 1.0 15.50286803489328 -7.268624664308252 24.07704056150786 1.111108055800773 1.437430393619814 0.649665532973742 0.11695687657728433 218.82571759787157 733254.5437172721 0.04831626229540503 0.033377921052564104 5.3873517914689874e-08 7.268624664308252 0.32632233781904096 S(ph)PSPSFR ddPTM_PC-9_Lapatinib_30min_R1 3 SPSPSFR 7 0 P49585;C9JEJ2 P49585 PCYT1A Choline-phosphate cytidylyltransferase A 1 S(0.994)PS(0.006)PSFR;S(0.999)PS(0.001)PSFR;S(0.999)PS(0.001)PSFR 120.87 0.0058682 100097500.0 68332.0 66580.0 64933.0 58484.0 64531.0 63488.0 56953.0 60693.0 75142.0 49641.0 True False 67357.57314944596 66425.83810066296 59594.45938862844 62785.10845690478 60735.41345282737 60772.76623775646 59901.74766683076 63513.018350689796 66678.71667966097 58221.38070752528 1.1569216039004002 1.1409182896976064 1.0235837533293966 1.07838576986529 1.0431805758425985 1.0438221405817916 1.0288616817204455 1.0908882197374712 1.145261686846986 1.0 15.829261432618514 -5.171034042672638 6.100048183648741 1.0589391280353024 1.1518109109339327 0.47486307536962946 0.03878035630157637 0.2033208042337369 11.11967379626422 0.009994033735238335 0.0273202149547586 6.744751561146244e-06 5.171034042672638 0.0928717828986303 S(ph)PSPSPTPEAK ddPTM_PC-9_Lapatinib_30min_R1 1 SPSPSPTPEAK 11 0 F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 F8VXC8 SMARCC2 SWI/SNF complex subunit SMARCC2 1 S(0.999)PS(0.001)PSPTPEAK 124.21 0.00052314 4908000.0 13024.0 18815.0 23012.0 21652.0 17213.0 21526.0 22449.0 22682.0 20963.0 14837.0 True False 12838.275371690917 18771.435023490154 21120.04218888882 23244.36030895462 16200.565182060069 20605.38315955686 23611.299376199404 23735.888524712 18601.926189823702 17401.55568094021 0.7377659565088529 1.0787216595841693 1.2136870160419875 1.3357633498488866 0.9309837280700382 1.1841115551597363 1.3568499167037507 1.3640095724722896 1.0689806435063876 1.0 14.086928666821864 -4.775726776214597 2.576016691613739 1.1968771554342932 0.6367530280192771 0.4683119640689549 0.14122460793274427 0.4467698783303021 3.7839701029717525 0.03730135723562987 0.5576338372004329 1.6759969493242715e-05 4.775726776214597 -0.560124127415016 S(ph)PSPTLGESLAPHK ddPTM_PC-9_AZD4547_30min_R2 1 SPSPTLGESLAPHK 14 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 S(0.481)PS(0.481)PT(0.037)LGESLAPHK 129.05 1.3469000000000001e-05 5526400.0 16399.0 17508.0 29032.0 46767.0 34820.0 33519.0 22570.0 42637.0 28301.0 33122.0 True False 21613.540879610096 23167.118612399525 28647.016710828197 35985.590692947284 29985.84403695028 31423.051631216687 24578.686276116438 36048.43135078977 29796.933082363405 31962.40886155216 0.6762175208142462 0.7248239240274358 0.8962721437835033 1.125872297323455 0.9381597040084326 0.9831252634095339 0.768987293247548 1.1278383774807634 0.9322492935820734 1.0 14.9640885212839 -5.317525729706337 3.252071524834325 0.9785757539490371 0.6904823627617183 0.5674557844494275 0.0969418750173208 0.1714110776529454 3.5876008151669425 0.02575421746748775 0.06660324068183944 4.813647347794894e-06 5.317525729706337 -0.2880933911873188 S(ph)PSPTLGESLAPHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSPTLGESLAPHK 14 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 S(0.484)PS(0.484)PT(0.033)LGESLAPHK;S(0.478)PS(0.478)PT(0.044)LGESLAPHK 140.22 5.7755e-05 7633600.0 39146.0 45713.0 58626.0 71142.0 74961.0 67766.0 69583.0 53314.0 64423.0 42822.0 True False 45772.64463125706 50251.08453330774 60023.866180343146 67156.14438547599 60272.93016204102 64212.23166477492 62991.59450270577 51914.563990852315 65365.0644986581 50585.28962123454 0.9048607801593521 0.993393235653503 1.1865873780654705 1.3275824827399108 1.191511022539245 1.2693854704712435 1.245255191269348 1.0262778839376216 1.292175353508688 1.0 15.626430284706245 -5.173955807527042 3.163629340308429 1.2038955362163095 0.9207812516428062 0.4854638276523727 0.10148558554478698 0.20153268902591348 3.809200629011389 0.025892320842048785 0.08652743665011714 6.699527782857388e-06 5.173955807527042 -0.2831142845735033 S(ph)PSPTLGESLAPHK ddPTM_PC-9_Lapatinib_30min_R1 1 SPSPTLGESLAPHK 14 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 S(0.439)PS(0.122)PT(0.439)LGESLAPHK 96.756 0.001627 3311200.0 13815.0 18639.0 25796.0 12103.0 22960.0 24181.0 22259.0 22848.0 26066.0 19456.0 True False 13617.995566639282 18595.842540676746 23675.1524554396 12993.094994424428 21609.537941096773 23146.834998664133 23411.462105876548 23909.60149072478 23130.172592851446 22818.943676509574 0.5967846610120698 0.8149300337604934 1.0375218411100873 0.5693994944998205 0.9469999245995863 1.0143692594540255 1.025966076158772 1.047796156985915 1.0136390588781836 1.0 14.477944388181578 -6.503916859206926 19.761268748951018 1.018913982992363 0.7765470992514496 0.5175892098087167 0.12087012041191518 44.327043636218534 46195.71401962102 0.037837507985427336 0.04196407210016119 3.133885614039633e-07 6.503916859206926 -0.24236688374091342 S(ph)PSPVLR ddPTM_PC-9_AZD4547_30min_R2 3 SPSPVLR 7 0 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3;O43432-2 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 S(0.926)PS(0.074)PVLR;S(0.974)PS(0.026)PVLR;S(0.735)PS(0.265)PVLR 107.01 0.0099709 128380000.0 159839.0 228638.0 256829.0 252090.0 238531.0 196554.0 200573.0 292718.0 200911.0 201927.0 True False 210664.47714226507 302540.762240222 253423.27965091253 193974.54525167483 205415.0879947672 184263.44730815888 218423.60843861394 247485.1590904721 211530.745292064 194857.59719179536 1.0811201625098108 1.5526249250750832 1.3005563206317887 0.9954682190848769 1.0541805449472943 0.945631322379446 1.1209396584297553 1.2700821659361643 1.0855658098044672 1.0 17.572060655454976 -5.677986116505122 6.232843474336757 1.0756971167262155 1.3414476815822556 0.4023987349227095 0.1350913359897741 0.19784872824383082 11.746956490032513 0.03692599861115364 0.06429494192033017 2.0990069834558407e-06 5.677986116505122 0.2657505648560401 S(ph)PSPVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSPVLR 7 0 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3;O43432-2 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 S(0.993)PS(0.007)PVLR;S(0.761)PS(0.239)PVLR 98.62899999999999 0.012101 87996000.0 87033.0 90319.0 113704.0 106434.0 94464.0 75016.0 79128.0 71948.0 70101.0 73612.0 True False 101765.96791989484 99285.27342252363 116415.13458482159 100470.84804368396 75954.45731549812 71082.02890187944 71632.42300288995 70059.4412352075 71126.09450693743 86957.27288772851 1.17029852179571 1.1417707815045206 1.3387624832154803 1.1554047718746077 0.8734687139230292 0.8174362711863588 0.8237657486726309 0.8056766146020014 0.8179430212671125 1.0 16.408019075514446 -6.2426455636507505 3.7341519563732564 0.83951850866193 1.2143240092333756 0.8486171771986136 0.0716379695103698 0.07862359578295793 2.433402737567473 0.02174237472890549 0.027258237311562405 5.719452221024237e-07 6.2426455636507505 0.37480550057144557 S(ph)PSPVLR ddPTM_PC-9_Lapatinib_30min_R1 3 SPSPVLR 7 0 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3;O43432-2 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 S(0.645)PS(0.355)PVLR;S(0.958)PS(0.042)PVLR;S(0.955)PS(0.045)PVLR 104.06 0.010406 116188000.0 113616.0 162631.0 173156.0 152854.0 144895.0 182871.0 144361.0 167583.0 157204.0 107955.0 True False 111995.8150053776 162254.43791151865 158919.7820814894 164095.39306599603 136372.56097453038 175050.03362312185 151835.306216202 175369.5179718193 139498.03008849156 126614.8779090046 0.8845391383299094 1.2814800329241516 1.255143034578461 1.2960198341298237 1.0770658490271452 1.3825392127213245 1.1991900851124524 1.3850624892428014 1.1017506978030323 1.0 16.950087413361103 -4.756838328277174 24.99605868972661 1.2353054539976123 0.8845386100638043 0.39780633992452497 0.12241995576997836 126.91707477991542 689416.4962021825 0.027720299058833435 0.21700013296758736 1.7504982128872942e-05 4.756838328277174 -0.35076684393380797 S(ph)PSPYYSR ddPTM_PC-9_AZD4547_30min_R2 4 SPSPYYSR 8 0 Q13595;Q13595-4;Q13595-3;P62995;H7C2L4;P62995-3;H7BXF3 Q13595;P62995 TRA2A;TRA2B Transformer-2 protein homolog alpha;Transformer-2 protein homolog beta 1 S(1)PSPYYSR;S(0.973)PS(0.027)PYYSR;S(0.998)PS(0.002)PYYSR;S(0.998)PS(0.002)PYYSR 117.31 0.0035521999999999997 110180000.0 51351.8 50295.4 57815.0 83868.0 69928.0 56263.2 42716.7 57978.6 58579.7 45521.6 True False 67680.60421620609 66552.40446984684 57048.33532435008 64533.5283476833 60219.70424514245 52745.05320974579 46518.403546787034 49019.3395856861 61676.10334917218 43927.902639696695 1.5407201379800135 1.5150371511182705 1.298681063657174 1.4690782957929283 1.3708759268356967 1.2007186785667574 1.0589716501681863 1.1159043942468674 1.4040302323343072 1.0 15.422849998407786 -6.711259316105554 2.752601856186119 1.151062115656939 1.4476133162917229 0.6094322284828324 0.11530315282463229 0.19509657182072873 3.0187013377363967 0.04262455406749476 0.04074060893533843 1.9441988588937996e-07 6.711259316105554 0.2965512006347839 S(ph)PSPYYSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPSPYYSR 8 0 Q13595;Q13595-4;Q13595-3;P62995;H7C2L4;P62995-3;H7BXF3 Q13595;P62995 TRA2A;TRA2B Transformer-2 protein homolog alpha;Transformer-2 protein homolog beta 1 S(1)PSPYYSR;S(0.999)PS(0.001)PYYSR;S(0.993)PS(0.007)PYYSR 128.6 0.0035428000000000005 74398000.0 58061.2 63078.2 57649.0 35246.600000000006 54381.0 67041.0 64372.0 35462.8 53200.0 28196.6 True False 67889.81439902773 69340.18682669908 59023.570795049985 33271.847273019004 43725.43342727486 63525.25194106458 58274.21814707867 34531.93907594249 53977.949355488105 33308.42037583722 2.0382177729531943 2.081761489866395 1.7720315202298575 0.9989019862723738 1.3127441329818934 1.907182965276475 1.7495341264922992 1.036733014844284 1.620549661209545 1.0 15.023599316570326 -5.5385811869166455 9.302859451630098 1.4094392410879926 2.027431673952653 0.46334419065072396 0.2992526069122797 0.19431417149330033 102.94987010725944 0.08410999249224005 0.14864301913006264 2.893468862059485e-06 5.5385811869166455 0.6179924328646602 S(ph)PSPYYSR ddPTM_PC-9_Lapatinib_30min_R1 4 SPSPYYSR 8 0 Q13595;Q13595-4;Q13595-3;P62995;H7C2L4;P62995-3;H7BXF3 Q13595;P62995 TRA2A;TRA2B Transformer-2 protein homolog alpha;Transformer-2 protein homolog beta 1 S(0.999)PS(0.001)PYYSR;S(1)PSPYYSR;S(0.982)PS(0.018)PYYSR;S(0.998)PS(0.002)PYYSR 125.71 0.0034603999999999998 97033000.0 37866.9 44739.7 68688.0 47354.9 63311.0 47443.9 40440.899999999994 32811.3 57459.0 46324.1 True False 37326.91106206102 44636.10797344897 63040.73778334766 50837.53731731551 59587.17145421507 45414.834994132674 42534.73192315659 34335.83278153968 50987.36234990603 54331.158962016736 0.6870258572646408 0.8215563375825345 1.160305411990564 0.9356976418054391 1.0967402976968124 0.8358893103289492 0.782879156928953 0.6319731336035751 0.9384552681004213 1.0 15.729492201653857 -6.97583910049192 24.897123827354985 0.8079045346793204 0.947708324014438 0.08585439454238208 0.15392994148397462 425.94187612382365 438919.61453181366 0.05550781805095026 0.048951317983345705 1.0572091165842807e-07 6.97583910049192 0.1398037893351176 S(ph)PSQESIGAR ddPTM_PC-9_AZD4547_30min_R2 1 SPSQESIGAR 10 0 Q8WXE0-2;Q8WXE0 Q8WXE0-2 CASKIN2 Caskin-2 1 S(0.998)PS(0.002)QESIGAR 101.56 0.0035567 7531200.0 1765.2 1607.5 2801.1 5667.2 5783.0 2376.4 1957.2 2466.6 3301.1 1792.9 True False 2326.496881559103 2127.0929386241837 2763.9555837937733 4360.714597367183 4980.130271846165 2227.803332331612 2131.387008401201 2085.443646829233 3475.589406670781 1730.1311167162878 1.3446939709255625 1.2294403112414463 1.5975411095083005 2.520453250759183 2.8784698591504623 1.28764999993751 1.2319222443941007 1.2053674005859814 2.008858966288807 1.0 10.756665660251517 S(ph)PSQESIGAR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSQESIGAR 10 0 Q8WXE0-2;Q8WXE0 Q8WXE0-2 CASKIN2 Caskin-2 1 S(0.993)PS(0.006)QESIGAR 74.392 0.025939999999999998 7224900.0 2474.7 6416.9 9375.1 6298.1 8148.6 6930.7 2832.2 6233.8 9863.2 2209.5 True False 2439.4103241955995 6402.042062303158 8604.315466932543 6761.2832838457 7669.315368763991 6634.290117250797 2978.837457938968 6523.445105605751 8752.302551899496 2591.409131026313 0.9413451141269557 2.4704868041302555 3.320323048921593 2.6091145558200344 2.9595154531722287 2.5601091073655837 1.149504886076872 2.517335077468905 3.377429849694632 1.0 11.339521090495 -10.097665815006737 6.801034152292254 1.0000509656426173 2.450055306952212 0.23892926500602196 0.7672634924771963 3.366073307604903e-09 1.6658978001811237e-09 0.7603318701521709 0.18440756536240074 7.986089720206375e-11 10.097665815006737 1.4500043413095947 S(ph)PSQGSYSR ddPTM_PC-9_AZD4547_30min_R2 1 SPSQGSYSR 9 0 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 S(0.997)PS(0.003)QGSYSR 79.23 0.042397000000000004 0.0 3106.5 8550.2 13559.0 15533.0 13168.0 12242.0 10807.0 16818.0 11763.0 11497.0 True False 4094.3023807859486 11313.884941725983 13379.198800706788 11952.106832457725 11339.850496225192 11476.505804748196 11768.802064066927 14219.164539193249 12384.768165359541 11094.49352941445 0.36903914270001287 1.0197748019528667 1.2059314618765586 1.0773008069966883 1.0221152021189823 1.0344326015713046 1.0607786676214381 1.2816416091004483 1.1162986514458033 1.0 13.437556188654456 -4.7653711287757075 4.159269968861321 1.1033895396108484 0.29749694077317534 0.8759924855237591 0.08195220635115164 0.07540388246394199 2.575607928186336 0.021496687352935716 0.1859414170351092 1.7164409660339644e-05 4.7653711287757075 -0.8058925988376731 down S(ph)PSQSSLPAVVVETFPATVNGTVEGGSGAGR ddPTM_PC-9_AZD4547_30min_R2 1 SPSQSSLPAVVVETFPATVNGTVEGGSGAGR 31 0 O00499-9;O00499-10 O00499-9 BIN1 Myc box-dependent-interacting protein 1 1 S(0.528)PS(0.132)QS(0.092)S(0.249)LPAVVVETFPATVNGTVEGGSGAGR 119.98 1.359e-17 3977600.0 14949.0 16766.0 23977.0 29980.0 26245.0 29021.0 19481.0 27212.0 20644.0 21930.0 True False 19702.471041483714 22185.28162300036 23659.0493137065 23068.574186382702 22601.334771676044 27206.312282273928 21214.771260302387 23007.01066955205 21735.199694438703 21162.23737497251 0.9310202268492089 1.0483429152551589 1.117984308298462 1.090082006813926 1.068003083568351 1.2856066114469276 1.0024824353114954 1.0871728854511982 1.0270747515640197 1.0 14.369204543822722 -1.6017845448330013 18.093512859147467 1.0742523520363843 0.005346083888325248 0.0 0.09006468664015335 0.0 0.0 0.020490523198422848 0.0 0.025015861004132334 1.6017845448330013 -1.068906268148059 S(ph)PSQSSLPAVVVETFPATVNGTVEGGSGAGR ddPTM_PC-9_Lapatinib_30min_R1 3 SPSQSSLPAVVVETFPATVNGTVEGGSGAGR 31 0 O00499-9;O00499-10 O00499-9 BIN1 Myc box-dependent-interacting protein 1 1 S(0.372)PS(0.372)QS(0.225)S(0.03)LPAVVVETFPATVNGTVEGGSGAGR;S(0.603)PS(0.166)QS(0.115)S(0.115)LPAVVVETFPATVNGTVEGGSGAGR;S(0.344)PS(0.303)QS(0.303)S(0.05)LPAVVVETFPATVNGTVEGGSGAGR 112.52 3.1564999999999996e-16 6520000.0 19719.2 22651.7 23736.1 25216.6 28319.600000000002 25841.4 23278.4 22695.600000000002 27771.9 18405.5 True False 19438.000591941614 22599.25138036629 21784.609481995656 27071.11288411164 26653.896806475812 24736.22356124561 24483.641649914036 23750.120430361254 24643.936170928075 21586.86615121285 0.9004549551463957 1.046898202919397 1.0091603537724116 1.254054789355826 1.2347274782624376 1.1458922933959923 1.1341915717830322 1.1002115945869644 1.1416171295222242 1.0 14.39786619649637 -5.195680964146095 1.6487221454631336 1.148190922696257 0.9185539452121531 0.4652511161895012 0.0758804987913789 0.43874853923835716 1.9160053280725304 0.02224698847630059 0.12390389621102071 6.372634873480648e-06 5.195680964146095 -0.22963697748410394 S(ph)PSSDSWTCADTSTER ddPTM_PC-9_AZD4547_30min_R2 2 SPSSDSWTCADTSTER 16 0 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHH7;H0YIQ0 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 S(0.956)PS(0.043)SDSWTCADTSTER;S(0.914)PS(0.083)S(0.003)DSWTCADTSTER 139.0 7.6174e-06 74218000.0 15003.7 17549.9 19224.3 21195.4 21181.6 17681.7 17272.4 22097.7 15940.2 13871.0 True False 19774.564503653037 23222.561968000362 18969.37322106552 16309.12799566566 18240.90046103002 16576.060503824217 18809.610138927503 18683.008219629588 16782.766429436735 13385.380512003814 1.4773255407957582 1.734919821455558 1.4171710101221302 1.2184284175589832 1.362747995447111 1.2383705109435663 1.4052353701905835 1.3957771467815157 1.253813174334954 1.0 13.708370531227283 -1.5228787452841523 0.04324924762722752 0.19158168162263114 3.351147813980501 0.5814754040009668 0.11853545272401807 523.7118696965175 1.7266798075992764 32.94557644683991 117.24684762590314 0.029999999999736484 1.5228787452841523 3.15956613235787 S(ph)PSSDSWTCADTSTER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPSSDSWTCADTSTER 16 0 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHH7;H0YIQ0 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 S(0.991)PS(0.005)S(0.003)DSWTCADTSTER;S(0.993)PS(0.006)SDSWTCADTSTER;S(0.999)PS(0.001)SDSWTCADTSTER 228.76 6.5335e-39 53878000.0 11314.8 11820.2 15978.6 8874.0 17887.6 14584.6 15069.0 10019.4 11088.6 12712.2 True False 13230.17216251334 12993.631339019637 16359.590423177955 8376.818549896176 14382.653187211 13819.75790127907 13641.555229887657 9756.401366431814 11250.7497974298 15016.821230280175 0.8810234842401796 0.865271760232389 1.0894176718432391 0.5578290119752518 0.9577694884060798 0.920285171499057 0.9084183010969453 0.6496981762530967 0.7492098111112621 1.0 13.874291834168625 -7.707028815062984 24.999972577061914 0.7745867472144211 0.8819469392664233 0.0536282287295039 0.14944814600215262 210.72426437818234 96820.61899072898 0.06830781533361725 0.03943749257862537 1.9632300139024672e-08 7.707028815062984 0.1073601920520022 S(ph)PSSDSWTCADTSTER ddPTM_PC-9_Lapatinib_30min_R1 2 SPSSDSWTCADTSTER 16 0 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHH7;H0YIQ0 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 S(1)PSSDSWTCADTSTER;S(1)PSSDSWTCADTSTER 311.26 2.0862999999999995e-129 68071000.0 11719.8 23579.0 21118.0 13163.1 19699.6 20217.3 19123.5 19551.800000000003 20624.6 13587.400000000001 True False 11552.673502851903 23524.404274189437 19381.759557837402 14131.158284814363 18540.908258903764 19352.653207828145 20113.621257995852 20460.2480053551 18301.64036133368 15935.963985927552 0.7249434996874763 1.4761833231402224 1.2162276204284035 0.8867463742571867 1.1634632379488645 1.2144011636144347 1.2621527807014017 1.2839040062730296 1.1484489032163456 1.0 13.959998671690167 -6.515368000901512 24.41998068552249 1.2028134565662696 1.1034326997323134 0.04891903654182228 0.19904589169468245 919.2590469037335 2988839.4671862666 0.06361549302137798 0.06632875869311357 3.052333611872792e-07 6.515368000901512 -0.0993807568339562 S(ph)PSSDSWTCADTSTERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSSDSWTCADTSTERR 17 1 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHH7;H0YIQ0 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 S(0.714)PS(0.144)S(0.114)DS(0.025)WT(0.002)CADTSTERR 52.045 0.032314999999999997 5113200.0 7692.1 9070.9 10449.0 11587.0 14037.0 11607.0 10788.0 14695.0 11343.0 10954.0 True False 8994.220604099848 9971.39900451034 10698.143788053167 10937.817955560851 11286.550615447622 10998.308487044285 9766.08254164365 14309.271820639507 11508.86991615229 12939.873488183715 0.6950779396964806 0.7705947831418837 0.8267579893901107 0.8452801308721389 0.8722303680754023 0.8499548698901572 0.7547278225371931 1.1058277991439625 0.8894113166300913 1.0 13.659535891867336 -2.189774536510152 0.15296190688838393 1.0443138720236933 3.241068642744195e-11 0.519067515789843 0.07868428898941307 45.23324384074556 0.5442885783611933 0.27814775272474906 10.13555754120212 0.006459895067205319 2.189774536510152 -1.0443138719912826 S(ph)PSSDSWTCADTSTERR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSSDSWTCADTSTERR 17 1 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHH7;H0YIQ0 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 S(0.88)PS(0.098)S(0.02)DS(0.002)WTCADTSTERR 68.41 0.0080061 6531100.0 0.0 2461.7 2409.9 2779.6 2476.8 2787.2 1895.4 1411.5 2533.4 0.0 True False 0.0 2456.0000848963973 2211.767324483016 2984.0210564737795 2331.1194935761555 2667.99795328054 1993.5345377365738 1477.0834429340875 2248.061814115316 0.0 0.0 S(ph)PSSEWLVR ddPTM_PC-9_AZD4547_30min_R2 2 SPSSEWLVR 9 0 Q9NWQ4-4;Q9NWQ4 Q9NWQ4-4 GPATCH2L G patch domain-containing protein 2-like 1 S(1)PSSEWLVR;S(0.999)PS(0.001)SEWLVR 146.11 0.00045592 16925800.0 10526.7 12189.9 12594.9 17345.1 14007.8 17443.4 11862.0 19154.7 10922.6 7457.0 True False 13873.971631037968 16130.046788513186 12427.883396638526 13346.455174123641 12063.058762228377 16352.66144049539 12917.695020261108 16194.78124621744 11499.946337070149 7195.932699734147 1.9280296536890265 2.2415505343885593 1.7270705432108437 1.85472206745579 1.6763718152441929 2.2724867119865557 1.7951383870972488 2.250546513145649 1.598117550139819 1.0 12.812965978448004 -8.56007607840797 5.8614594913048 1.000088439060306 1.9590441459277128 0.6724041131238205 0.20874553458701933 0.14795291187096662 20.28085464884286 0.19422650584288687 0.050359362767484 2.7537462680513354e-09 8.56007607840797 0.9589557068674068 S(ph)PSSEWLVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSSEWLVR 9 0 Q9NWQ4-4;Q9NWQ4 Q9NWQ4-4 GPATCH2L G patch domain-containing protein 2-like 1 S(0.996)PS(0.004)SEWLVR 86.189 0.011855 2101500.0 12293.0 13872.0 14331.0 14378.0 14101.0 14057.0 20520.0 14874.0 14724.0 16018.0 True False 14373.962102182677 15249.12048314582 14672.705390620156 13572.447274104929 11338.010274875474 13319.82617406578 18576.19704806523 14483.5732603057 14939.310644928704 18921.936601581758 0.7596454001955119 0.8058963944457507 0.7754335985563765 0.7172863729482296 0.5991992528887179 0.703935672892611 0.9817281095061049 0.7654382088509356 0.7895233431698461 1.0 14.207772131150568 -9.148844809216937 0.4755110961005002 1.0155130168739221 0.7397699455369463 0.4098677852389234 0.08824226515794906 2.7108952593719287 1.024709234609473 0.1996419139672746 0.05384124119030554 7.098313737804419e-10 9.148844809216937 -0.27574307133697584 S(ph)PSSEWLVR ddPTM_PC-9_Lapatinib_30min_R1 2 SPSSEWLVR 9 0 Q9NWQ4-4;Q9NWQ4 Q9NWQ4-4 GPATCH2L G patch domain-containing protein 2-like 1 S(0.999)PSSEWLVR;S(0.999)PSSEWLVR 141.91 0.0006911 13284600.0 8181.0 8885.0 13315.099999999999 7444.9 6940.0 8193.5 8059.6 10848.5 10859.400000000001 4462.7 True False 8064.337439788344 8864.427328392769 12220.383875772362 7992.422781458358 6531.802844564973 7843.083104981373 8476.886652074329 11352.56091439636 9636.300017448439 5234.071748826035 1.540738802748953 1.6936006523756568 2.3347757658295967 1.526999086944309 1.247939110890104 1.4984668688847302 1.619558741046229 2.1689731167599406 1.841071441103151 1.0 12.353717985694201 S(ph)PSSKPSLAVAVDSAPEVAVK ddPTM_PC-9_AZD4547_30min_R2 1 SPSSKPSLAVAVDSAPEVAVK 21 1 Q5SRN1;O60508 Q5SRN1 CDC40 Pre-mRNA-processing factor 17 1 S(0.401)PS(0.268)S(0.268)KPS(0.062)LAVAVDS(0.001)APEVAVK 56.946999999999996 0.0071048000000000005 19664000.0 22943.0 33528.0 26332.0 24332.0 28740.0 37663.0 33885.0 36181.0 39808.0 32427.0 True False 30238.396755954298 44365.270324225006 25982.82047497684 18722.633325652572 24749.947088510944 35307.926656120835 36900.699356057 30590.0578066685 41912.16961035731 31291.740600010642 0.9663379593509738 1.417794902857207 0.8303411691635972 0.5983250840845269 0.7909418464405437 1.1283465214494597 1.1792472597719428 0.9775761021954176 1.3394003914995722 1.0 14.933494290130868 -6.7906266411891565 23.609533455915788 1.126908667905218 0.9254269265708962 0.18304483811293537 0.21552802043457137 230.20129038839494 186206.91884547792 0.08310478105001953 0.07330770194864286 1.6194716836766192e-07 6.7906266411891565 -0.20148174133432184 S(ph)PSSKPSLAVAVDSAPEVAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSSKPSLAVAVDSAPEVAVK 21 1 Q5SRN1;O60508 Q5SRN1 CDC40 Pre-mRNA-processing factor 17 1 S(0.375)PS(0.284)S(0.284)KPS(0.057)LAVAVDS(0.001)APEVAVK 74.665 0.00072362 15716000.0 29324.0 41968.0 32007.0 33557.0 36128.0 25007.0 37087.0 24108.0 23027.0 20064.0 True False 34287.97402459975 46134.30568315054 32770.16826722344 31676.910083261868 29048.977747018016 23695.588897692476 33573.85087337208 23475.19054453741 23363.72631219595 23701.4443734634 1.4466617934470372 1.9464765503828707 1.3826232591931638 1.3364970330132266 1.2256205693329736 0.9997529485680847 1.4165318511542706 0.9904540067111138 0.9857511611551587 1.0 14.532687359640837 -5.813199819347081 1.2439254659218597 1.0990500149848301 1.7032307297361182 0.6214562214293393 0.17769823908867868 0.31142315112098734 0.9610737716294702 0.06176931630443285 0.14863096410256477 1.5374470965214534e-06 5.813199819347081 0.6041807147512881 S(ph)PSSKPSLAVAVDSAPEVAVK ddPTM_PC-9_Lapatinib_30min_R1 1 SPSSKPSLAVAVDSAPEVAVK 21 1 Q5SRN1;O60508 Q5SRN1 CDC40 Pre-mRNA-processing factor 17 1 S(0.776)PS(0.109)S(0.109)KPS(0.005)LAVAVDSAPEVAVK 105.79 3.8023000000000005e-05 17992000.0 49447.0 64603.0 48135.0 51663.0 67777.0 59911.0 75498.0 70436.0 59421.0 57995.0 True False 48741.876712530735 64453.41572269646 44177.5261064733 55462.469362715834 63790.49011470893 57348.74618936222 79406.91702544889 73708.71369926006 52728.381249130114 68019.35847651988 0.7165883037452686 0.947574590033007 0.6494846040296496 0.815392420701253 0.9378284585957873 0.8431238911075422 1.1674164356145753 1.0836431767392238 0.7751966856219591 1.0 16.05365777890441 -6.5910611873753195 1.575812013333237 1.0024410519878237 0.7849650846753568 0.3522701428812519 0.12491296234181172 0.4277798065495153 2.1836971196639268 0.05123372345541778 0.053382855301846346 2.5641227540226404e-07 6.5910611873753195 -0.217475967312467 S(ph)PSSLLIANLHLQ ddPTM_PC-9_AZD4547_30min_R2 2 SPSSLLIANLHLQ 13 0 Q658Y4 Q658Y4 FAM91A1 Protein FAM91A1 1 S(0.798)PS(0.131)S(0.071)LLIANLHLQ;S(0.985)PS(0.01)S(0.005)LLIANLHLQ 138.31 6.3485e-05 10215200.0 23725.1 27888.0 33633.0 53601.0 45643.0 41969.0 29928.0 36657.0 31796.0 37052.0 True False 31269.188287263685 36902.25062043625 33187.00444458819 41244.117577194804 39306.25730552905 39344.67179541553 32591.534021781717 30992.50294406033 33476.67164717945 35754.820757751084 0.8745446802578367 1.032091612777458 0.9281826545695594 1.1535260617480154 1.099327488503996 1.1004018748125377 0.911528385014107 0.8668062735943556 0.9362841412069514 1.0 15.125850150515234 -10.78155794246666 6.76827309568385 1.0000000565211902 0.9941159961316024 0.0 0.09707593426262712 9.019245301787054e-08 9.803539699780926e-09 0.10236399957667208 0.024826678185811617 1.6536441450515102e-11 10.78155794246666 -0.005884060389587775 S(ph)PSSQTPNSR ddPTM_PC-9_AZD4547_30min_R2 4 SPSSQTPNSR 10 0 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 S(1)PSSQTPNSR;S(1)PSSQTPNSR;S(0.994)PS(0.005)S(0.001)QTPNSR;S(0.995)PS(0.003)S(0.002)QTPNSR 114.71 0.001185 93748200.0 79881.0 64714.7 91285.0 130664.1 109643.8 104266.9 101780.20000000001 93851.09999999999 83514.4 94779.5 True False 105281.49637198205 85632.46121006692 90074.50125544055 100541.51048522115 94421.65095975221 97747.0742601782 110838.44062562664 79348.56897872996 87928.80068597327 91461.29855363454 1.1511043254021056 0.9362699039293709 0.9848373320724203 1.099279280692279 1.03236726848331 1.0687260710917805 1.211861654912203 0.8675644259762892 0.9613771297420434 1.0 16.48087378200495 -7.789324959663278 24.999853371219125 0.9358531177731783 1.060570025254913 0.3385228143426384 0.08003851835600609 265.1596778995982 237716.12484430315 0.044075974092713376 0.021180467424715486 1.624332898258949e-08 7.789324959663278 0.1247169074817348 S(ph)PSSQTPNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPSSQTPNSR 10 0 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 S(0.999)PSSQTPNSR;S(0.999)PS(0.001)SQTPNSR;S(0.998)PS(0.001)SQTPNSR;S(0.999)PS(0.001)SQTPNSR 110.98 0.0016618 111748000.0 121509.09999999999 84129.6 120891.20000000001 130333.5 153725.9 151440.7 131941.0 129341.5 130900.2 108017.2 True False 142078.19071588074 92481.43069484318 123773.70469042932 123031.33654190786 123604.41342560673 143498.88309588414 119442.59330988153 125946.42267364706 132814.36778615165 127599.86329631529 1.1134666373892859 0.7247768791106045 0.9700143988634159 0.9641964604319497 0.9686876633916901 1.124600602138952 0.9360714833409283 0.9870419875072391 1.0408660664292964 1.0 16.96126725791394 -5.955224294671706 1.952839342741656 1.010762599687179 0.9134064338267202 0.09767250093357915 0.09977872401446276 0.6482933680320547 4.998682861266232 0.030673099271890752 0.05100583474042673 1.1086021214341294e-06 5.955224294671706 -0.09735616586045881 S(ph)PSSQTPNSR ddPTM_PC-9_Lapatinib_30min_R1 3 SPSSQTPNSR 10 0 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 S(0.999)PS(0.001)SQTPNSR;S(0.996)PS(0.004)SQTPNSR;S(0.962)PS(0.025)S(0.012)QT(0.002)PNSR 108.98 0.0019491 48227300.0 64360.3 73376.6 83604.3 67867.4 81634.4 72359.0 62096.1 70559.4 86478.5 52695.5 True False 63442.510319766465 73206.70099094504 76730.67717593056 72858.59499500968 76832.8250914055 69264.3742470675 65311.13221944923 73837.84731375374 76738.38067102377 61803.84696265988 1.0265139378475359 1.184500716196104 1.2415194352268888 1.1788682837013167 1.2431722112350982 1.1207129920070358 1.056748656097546 1.1947128041781032 1.2416440794921213 1.0 15.915409020611452 S(ph)PSTLLPK ddPTM_PC-9_AZD4547_30min_R2 4 SPSTLLPK 8 0 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 S(0.998)PS(0.002)T(0.001)LLPK;S(0.997)PS(0.002)T(0.001)LLPK;S(0.933)PS(0.04)T(0.026)LLPK;S(0.975)PS(0.023)T(0.002)LLPK 117.53 0.0035428000000000005 329646000.0 468709.0 546736.0 555573.0 563030.0 570430.0 612680.0 542908.0 637580.0 506409.0 517590.0 True False 617748.71224716 723457.7199947947 548205.7390150505 433232.13222678634 491235.6408385273 574369.0227457207 591225.7602478422 539056.6611308607 533176.7458855367 499469.3316421347 1.2368100964600794 1.4484527360593697 1.097576376136413 0.8673848518435028 0.9835151223869201 1.1499585387101423 1.1837078330796296 1.0792587792298927 1.067486454338608 1.0 18.930036570980747 -5.364678929322106 5.966125558656232 1.052992622396374 1.3404049789938703 0.593226303362854 0.09619990397824389 0.15572142748039783 7.4460162199501 0.02729172610693392 0.057896421378632976 4.318382136225381e-06 5.364678929322106 0.2874123565974964 S(ph)PSTLLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSTLLPK 8 0 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 S(0.947)PS(0.049)T(0.004)LLPK;S(0.992)PS(0.007)T(0.001)LLPK 89.029 0.010532 162189000.0 482980.0 430310.0 470450.0 394940.0 473680.0 398080.0 414570.0 311680.0 328620.0 342140.0 True False 564738.9747101746 473028.3329802822 481667.3121915613 372812.79221275594 380865.80434033135 377203.98402021057 375298.92837311904 303498.73025225766 333425.4458120399 404167.27362124954 1.3972902101900484 1.1703776229630192 1.1917523847884282 0.9224220181719208 0.9423469667097433 0.9332868063278508 0.9285732736609857 0.7509235657132158 0.8249689363134761 1.0 18.624592982458765 -4.959744560096002 0.6237359995795122 0.8581962756448908 1.6383805700003415 0.8224273047746485 0.07710733434704538 1.1326849882582695 0.38852079598995953 0.03867727535629237 0.6139837205592927 1.0971233037415256e-05 4.959744560096002 0.7801842943554508 S(ph)PSTLLPK ddPTM_PC-9_Lapatinib_30min_R1 4 SPSTLLPK 8 0 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 S(0.999)PSTLLPK;S(0.962)PS(0.036)T(0.003)LLPK;S(0.964)PS(0.034)T(0.003)LLPK;S(0.993)PS(0.005)T(0.002)LLPK 110.81 0.0037561 281883000.0 491791.0 502253.0 527877.0 407092.0 515933.0 490965.0 492445.0 461536.0 483246.0 395593.0 True False 484777.97015657683 501090.06403683126 484476.99072414613 437030.90369910205 485586.835303305 469967.5714453139 517941.3925481098 482980.6474800063 428817.7466740232 463970.72295546095 1.0448460348286097 1.080003627911957 1.0441973313274202 0.9419363810613866 1.0465893886798523 1.0129250579684284 1.1163234379291422 1.0409722501528835 0.9242344946734662 1.0 18.823674247075076 -1.5228788260662722 0.07911415148039622 0.9623805082355565 1.1989403205894413 0.08863106108223606 0.052871621346214884 624.2502275397638 3.6186842827368113 1.6554554096694638 16.167051986051767 0.029999994419505852 1.5228788260662722 0.2365598123538848 S(ph)PSTTYLHTPTPSEDAAIPSK ddPTM_PC-9_AZD4547_30min_R2 3 SPSTTYLHTPTPSEDAAIPSK 21 0 Q13111 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 S(0.581)PS(0.136)T(0.136)T(0.136)Y(0.01)LHTPTPSEDAAIPSK;S(0.616)PS(0.128)T(0.128)T(0.128)Y(0.001)LHTPTPSEDAAIPSK;S(0.203)PS(0.203)T(0.203)T(0.203)Y(0.176)LHT(0.012)PT(0.001)PSEDAAIPSK 179.17 4.7989e-13 148326000.0 125611.0 123032.0 195858.0 236860.0 207416.0 197916.0 164220.0 215097.0 163648.0 185433.0 True False 165552.68512889245 162799.68797810943 193260.79494865637 182255.58645052047 178619.86866077222 185540.28123284964 178835.2618637059 181858.70108733798 172298.09918598633 178941.04711141213 0.9251800400263455 0.9097951007112819 1.0800249471454613 1.0185230800457128 0.9982051158422028 1.0368793757942452 0.9994088262619791 1.0163051129018446 0.9628763325538731 1.0 17.449124838190663 -5.237561722261068 24.995776443785523 1.0144996396215291 0.9174875393713042 0.6423810276401729 0.028810877629275977 468.9566822964286 490914.9713396279 0.007227816705535516 0.019100016506592675 5.786797401012252e-06 5.237561722261068 -0.09701210025022489 S(ph)PSTTYLHTPTPSEDAAIPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPSTTYLHTPTPSEDAAIPSK 21 0 Q13111 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 S(0.895)PS(0.033)T(0.033)T(0.033)Y(0.006)LHTPTPSEDAAIPSK;S(0.207)PS(0.207)T(0.207)T(0.207)Y(0.171)LHT(0.001)PTPSEDAAIPSK;S(0.612)PS(0.129)T(0.129)T(0.129)YLHTPTPSEDAAIPSK;S(0.68)PS(0.076)T(0.076)T(0.076)Y(0.061)LHT(0.031)PTPSEDAAIPSK 176.27 8.255700000000001e-13 121049500.0 173071.0 207763.0 277677.0 279281.0 305439.0 272023.0 282237.0 233073.0 266667.0 215623.0 True False 202368.50199193542 228388.33758216715 284297.87277588714 263633.7910112186 245590.42056220773 257757.63501087672 255501.46814107106 226955.08071125596 270566.5003906006 254713.7430292711 0.7944938486050975 0.8966470943655416 1.116146578487586 1.035019892825031 0.9641820564585125 1.0119502463644288 1.0030925897536256 0.8910201625248576 1.0622375423202342 1.0 17.9585172764725 -5.012165125745805 5.349266460065879 1.0060637583822456 0.8137889760256536 0.6026368539738007 0.056291667504278546 0.10360184814751429 9.93570654407866 0.014587507663440635 0.04929923273837028 9.723774399433044e-06 5.012165125745805 -0.192274782356592 S(ph)PSTTYLHTPTPSEDAAIPSK ddPTM_PC-9_Lapatinib_30min_R1 4 SPSTTYLHTPTPSEDAAIPSK 21 0 Q13111 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 S(0.21)PS(0.21)T(0.21)T(0.21)Y(0.161)LHTPTPSEDAAIPSK;S(0.308)PS(0.212)T(0.212)T(0.212)Y(0.055)LHT(0.002)PTPSEDAAIPSK;S(0.571)PS(0.048)T(0.048)T(0.048)Y(0.004)LHT(0.222)PT(0.049)PS(0.009)EDAAIPSK;S(0.749)PS(0.073)T(0.073)T(0.081)Y(0.023)LHTPTPSEDAAIPSK 125.23 3.8062e-06 146942000.0 229415.0 185830.0 253855.0 209302.0 227885.0 244973.0 212474.0 218944.0 269448.0 178096.0 True False 226143.50003044194 185399.72205236097 232984.02180863754 224694.7672910039 214481.2523391482 234496.07584995436 223474.8640767337 229116.9375343684 239099.92882677165 208879.65630199676 1.0826497133999744 0.8875910911319738 1.1153983395673097 1.07571398416197 1.0268173365291864 1.122637216095959 1.0698737638367009 1.0968848838161276 1.1446779119603807 1.0 17.67231246334051 -5.289505680142342 24.995861055871472 1.0838549134247575 0.9851203342194192 0.29194365449934 0.059949056947760725 705.2132781203256 628061.9406249116 0.014588781266178843 0.030379105957942562 5.134454621001625e-06 5.289505680142342 -0.09873457920533824 S(ph)PSVAAMASPQLCR ddPTM_PC-9_AZD4547_30min_R2 2 SPSVAAMASPQLCR 14 0 P25325-2 P25325-2 MPST 3-mercaptopyruvate sulfurtransferase 1 S(0.975)PS(0.024)VAAMAS(0.001)PQLCR;S(0.984)PS(0.016)VAAMASPQLCR 82.925 0.007635300000000001 7559600.0 12627.1 12188.3 13297.8 19012.6 13929.0 15968.099999999999 15017.1 18010.7 16393.6 18267.9 True False 16642.255140003937 16127.929619802891 13121.462483371832 14629.538811741826 11995.198782041356 14969.612182715215 16353.592808022515 15227.560159712682 17260.132227802278 17628.346381316 0.9440621814444714 0.9148861311743127 0.7443388165596211 0.8298871882417421 0.6804494603506811 0.8491784685250605 0.9276872858225331 0.8638110365162853 0.9791123826620524 1.0 14.105609529229403 -8.011414254840771 1.110901863768376 0.9978291559561713 0.8250733997173967 0.3834327915830985 0.07585493060635967 0.5542197401219674 1.2565453663358281 0.07447614624114772 0.026409263596806763 9.740600804088515e-09 8.011414254840771 -0.1727557562387746 S(ph)PSVAAMASPQLCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPSVAAMASPQLCR 14 0 P25325-2 P25325-2 MPST 3-mercaptopyruvate sulfurtransferase 1 S(0.959)PS(0.041)VAAMASPQLCR;S(0.707)PS(0.285)VAAMAS(0.007)PQLCR;S(0.715)PS(0.285)VAAMAS(0.001)PQLCR 92.65 0.0035781 39033800.0 41157.4 43520.0 47563.0 41114.6 48718.0 38693.9 34255.8 38063.6 36496.3 31570.3 True False 48124.534924296226 47840.37798633988 48697.082303681964 38811.08225733169 39172.05762508922 36664.723767282056 31010.842633485026 37064.470831717874 37029.98934328385 37293.74547964269 1.2904183879992872 1.2827989618917257 1.3057707580018731 1.0406860924847912 1.0503653393159942 0.9831333188911263 0.8315293150271733 0.9938521957240801 0.9929276039999035 1.0 15.18664607646125 -5.9102200083325345 1.760307683058014 0.9617695512917157 1.3043114520343613 0.8594955509963232 0.05700047726499513 0.12445429139710074 0.7841506713686974 0.019160957553263035 0.034354143993828135 1.229645689367027e-06 5.9102200083325345 0.34254190074264557 S(ph)PSVAAMASPQLCR ddPTM_PC-9_Lapatinib_30min_R1 2 SPSVAAMASPQLCR 14 0 P25325-2 P25325-2 MPST 3-mercaptopyruvate sulfurtransferase 1 S(0.96)PS(0.04)VAAMASPQLCR;S(0.782)PS(0.216)VAAMAS(0.001)PQLCR 95.822 0.0027319 5326300.0 15046.5 13673.0 14951.2 13262.7 11647.8 13364.599999999999 15341.8 14512.2 14796.400000000001 11466.5 True False 14831.93415080984 13641.341008566618 13721.97004930099 14238.083201070222 10962.699304455882 12793.027212404235 16136.123335996066 15186.489791390766 13129.873619000511 13448.469246849156 1.1028715520381487 1.014341540154293 1.0203369467135386 1.0587140394737538 0.8151633545226223 0.9512627034040707 1.1998483277029168 1.1292355667132012 0.9763098965390958 1.0 13.7151543489366 -7.226783733957232 24.968403940710264 1.0871181810391581 0.9907557387565725 0.15653977513949735 0.09239157987625903 1043.4639753434824 751786.8614918247 0.036951729306340796 0.02862097408401021 5.93220657704322e-08 7.226783733957232 -0.09636244228258561 S(ph)PSVDSAR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSVDSAR 8 0 C9JJX6;E9PDC3;O00192-2;O00192 C9JJX6 ARVCF Armadillo repeat protein deleted in velo-cardio-facial syndrome 1 S(0.998)PS(0.002)VDSAR 78.098 0.022608 2999700.0 8430.0 11606.0 9565.8 6113.1 9259.0 7503.3 8972.0 7870.2 9719.0 6854.6 True False 8309.786654127332 11579.127020070511 8779.336849055831 6562.67776670379 8714.403823894385 7182.401350046591 9436.526259666838 8235.878223577654 8624.343874392815 8039.408476819618 1.0336316008929398 1.4402958940893624 1.0920376635133893 0.8163135118244395 1.0839608223690849 0.8933992308956469 1.1737836542172961 1.0244383336565777 1.0727585119302951 1.0 12.972873639430297 -5.511965285744111 24.93567564268117 1.0106882829982224 1.2442645347703973 0.3234193850380741 0.13055948139740897 500.58677817972887 1143766.6857281663 0.03285833579947775 0.06229015986693111 3.07634270476304e-06 5.511965285744111 0.2335762517721749 S(ph)PSVSPSKQPVSTSSK ddPTM_PC-9_Lapatinib_30min_R1 1 SPSVSPSKQPVSTSSK 16 1 Q96JG6;H0Y7Q2;Q96JG6-3 Q96JG6 CCDC132 Coiled-coil domain-containing protein 132 1 S(0.873)PS(0.076)VS(0.042)PS(0.009)KQPVSTSSK 53.958 0.033974000000000004 6364200.0 92094.0 61679.0 56383.0 48939.0 45888.0 59482.0 44890.0 47307.0 60722.0 43103.0 True False 90780.7226720286 61536.18606504647 51747.40738467403 52538.13731571816 43188.958059279124 56938.09351931437 47214.184551543105 49505.05592269422 53882.84892899279 50553.29611886266 1.795742901878877 1.2172536864927752 1.0236208389459658 1.0392623498216353 0.8543252641278177 1.126298340378035 0.9339486873522842 0.9792646518299464 1.065862229879167 1.0 15.62551753971551 -4.637511746217847 1.736800391081244 0.9962730353820082 2.306319924261331 0.9219049145702909 0.06967155033409192 0.32789963579904524 0.7421555929314839 0.018248218401165854 0.802531666423755 2.30403065886517e-05 4.637511746217847 1.3100468888793226 S(ph)PSWQRPNQGVPSTGR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSWQRPNQGVPSTGR 16 1 Q96HC4;Q96HC4-7;Q96HC4-4;H0Y8Y3;Q96HC4-6;A0A0A0MSP3 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 1 S(0.659)PS(0.341)WQRPNQGVPSTGR 65.92399999999999 0.013028999999999999 35447000.0 12668.0 13378.0 5718.6 3842.0 10897.0 5718.1 10497.0 5659.2 6299.4 5688.8 True False 12487.351996973319 13347.024062941864 5248.438782434368 4124.553496536286 10256.059884326294 5473.5501925421395 11040.483297784538 5922.1470919253225 5589.895236377212 6672.101500150478 1.8715770431087846 2.000422814707007 0.786624541355673 0.6181790694346097 1.5371558547325734 0.820363747826482 1.654723522646581 0.8875984713049941 0.8378012888819424 1.0 12.70392552078428 -5.254302182351521 24.99119633423664 1.033762859419173 1.936000046370531 0.5769704642081936 0.31424969674032077 386.92014925845507 1354808.413846414 0.08042240061767822 0.20351042030041128 5.5679819361202605e-06 5.254302182351521 0.9022371869513579 S(ph)PSYTNDSTATFIIDGMHCK ddPTM_PC-9_AZD4547_30min_R2 2 SPSYTNDSTATFIIDGMHCK 20 0 Q04656-5;Q04656;Q04656-2;Q04656-3 Q04656-5 ATP7A Copper-transporting ATPase 1 1 S(0.429)PS(0.311)Y(0.243)T(0.016)NDS(0.001)TATFIIDGMHCK;S(0.74)PS(0.227)Y(0.012)T(0.019)NDS(0.002)TATFIIDGMHCK 90.755 0.00046204 19543600.0 30845.0 44959.0 58726.0 45403.0 45829.0 47208.0 50516.0 60599.0 44076.0 39165.0 True False 40653.06838414375 59491.11752883655 57947.25486911324 34936.0398193574 39466.43441612274 44256.0762972188 55011.8261375409 51234.816976487746 46405.7673770626 37793.845270898215 1.0756531412125767 1.574095387818226 1.5332458090400616 0.924384369172899 1.0442555959372688 1.1709863333566801 1.4555763178694274 1.3556391684743248 1.2278657290475727 1.0 15.205863690183126 -5.7344084896805505 24.999808642385158 1.1901072812496118 1.4123077950449456 0.21234154607476574 0.19540367775853262 373.99657830320325 345891.97670853214 0.056202162564229996 0.09731326169900506 1.8432808463090258e-06 5.7344084896805505 0.2222005137953338 S(ph)PSYTNDSTATFIIDGMHCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSYTNDSTATFIIDGMHCK 20 0 Q04656-5;Q04656;Q04656-2;Q04656-3 Q04656-5 ATP7A Copper-transporting ATPase 1 1 S(0.713)PS(0.235)Y(0.022)T(0.008)NDS(0.007)T(0.013)AT(0.001)FIIDGMHCK 71.426 0.0025989999999999997 8223800.0 13702.0 16803.0 19893.0 19432.0 30778.0 25886.0 24927.0 15449.0 18079.0 18654.0 True False 16021.477973164161 18471.09079284165 20367.324564622624 18343.288039394003 24747.271841721664 24528.492590301397 22565.734104148247 15043.480119568547 18343.371172892294 22035.82253501726 0.7270651207915807 0.8382301483636077 0.9242824737881594 0.8324303760499329 1.1230473381420467 1.1131189930089072 1.0240477326539048 0.6826829402743129 0.8324341487023109 1.0 14.427563128901019 -2.6046427530646588 19.041488950292635 0.9119404934898802 0.3342127560254715 0.0 0.14502688871976185 0.0 0.0 0.03606322084458701 0.0 0.0024851765497462433 2.6046427530646588 -0.5777277374644086 S(ph)PSYTNDSTATFIIDGMHCK ddPTM_PC-9_Lapatinib_30min_R1 2 SPSYTNDSTATFIIDGMHCK 20 0 Q04656-5;Q04656;Q04656-2;Q04656-3 Q04656-5 ATP7A Copper-transporting ATPase 1 1 S(0.722)PS(0.224)Y(0.047)T(0.007)NDSTATFIIDGMHCK;S(0.805)PS(0.093)Y(0.076)T(0.018)NDS(0.003)T(0.002)AT(0.003)FIIDGMHCK 71.857 0.0024649 8899800.0 43546.0 48781.0 39003.0 30428.0 32540.4 42368.0 30486.0 28871.0 48527.0 25770.0 True False 42925.02605464161 48668.05059159573 35796.323895933885 32665.776624832393 30626.437648887877 40556.019404631836 32064.415910856384 30212.452058767303 43061.378248035806 30224.31016363343 1.4202152446903475 1.6102286645454766 1.184355365006968 1.0807782360616651 1.013304769673066 1.3418344102830757 1.0608816458427233 0.9996076633411342 1.4247265864763468 1.0 14.883421791484976 -5.339797898624055 5.508010438850147 1.1333374692316514 1.5137174097618027 0.5261849804415106 0.1434625224640582 0.1488317668867458 7.772407027115206 0.036364010886186196 0.07826690889387675 4.573009476709407e-06 5.339797898624055 0.38037994053015134 S(ph)PTAALNESLVECPK ddPTM_PC-9_AZD4547_30min_R2 2 SPTAALNESLVECPK 15 0 Q53EZ4 Q53EZ4 CEP55 Centrosomal protein of 55 kDa 1 S(0.961)PT(0.039)AALNESLVECPK;S(0.996)PT(0.004)AALNESLVECPK 225.17 2.7789000000000003e-24 52495000.0 56819.0 51269.0 59522.0 58138.0 54176.0 64720.0 51536.0 75625.0 52967.0 49353.0 True False 74886.26009138155 67840.7016300612 58732.69938901611 44735.182323146044 46654.59754583049 60673.04816886966 56122.60416153907 63938.89393961759 55766.72748572632 47625.16649188409 1.5724094130808568 1.424471694846927 1.233228221869311 0.9393181298540859 0.9796206708018753 1.2739703110373186 1.1784232643281793 1.342544260722187 1.1709508143185106 1.0 15.539436515653481 -5.196392757571264 2.5788459342138337 1.1407259641662075 1.548580008495199 0.5919494761775946 0.12328471535247529 0.231159919951778 2.8894667090111206 0.03650409215820378 0.13420767642132672 6.362198902841816e-06 5.196392757571264 0.4078540443289915 S(ph)PTAALNESLVECPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPTAALNESLVECPK 15 0 Q53EZ4 Q53EZ4 CEP55 Centrosomal protein of 55 kDa 1 S(0.994)PT(0.006)AALNESLVECPK;S(0.998)PT(0.002)AALNESLVECPK 226.79 2.1830000000000002e-24 17898000.0 46051.0 54155.0 45816.3 52270.0 63275.0 59381.0 70022.0 66899.0 61424.0 54733.0 True False 53846.52475129055 59531.150502073375 46908.73435128536 49341.48136162645 50876.717973388055 56266.95582572388 63389.009244620975 65142.972135349664 62322.20979720867 64655.65963381043 0.8328199736304686 0.9207415226948317 0.7255162907154897 0.7631424942701269 0.7868873082656334 0.8702556921451647 0.9804092882763339 1.0075370432271393 0.963909581159365 1.0 15.980489041437322 -7.130124215209484 2.7554380079621317 0.9908634143296023 0.8059138918530369 0.7550796312777427 0.04891645120049533 0.15042681414154896 2.2093567100455145 0.022768899842797917 0.01685566913990169 7.410982449630865e-08 7.130124215209484 -0.1849495224765655 S(ph)PTAALNESLVECPK ddPTM_PC-9_Lapatinib_30min_R1 4 SPTAALNESLVECPK 15 0 Q53EZ4 Q53EZ4 CEP55 Centrosomal protein of 55 kDa 1 S(0.929)PT(0.071)AALNESLVECPK;S(0.929)PT(0.071)AALNESLVECPK;S(0.91)PT(0.09)AALNESLVECPK;S(0.976)PT(0.024)AALNESLVECPK 149.22 9.779199999999999e-10 42270000.0 50574.4 58554.0 60500.0 56313.1 74676.2 88755.8 90000.4 88690.1 89746.7 83487.6 True False 49853.19978179094 58418.42181054702 55525.923536753595 60454.5532289947 70283.892735058 84959.92133387523 94660.18033666073 92810.96582512838 79638.48157135192 97918.32041976592 0.5091304626966162 0.5966035932817594 0.5670636842903308 0.6173977757158431 0.7177808241987615 0.8676611380757008 0.9667259398533607 0.9478406638028223 0.81331543709032 1.0 16.579291191431565 -6.565934382682481 1.544976258504189 0.931146300830596 0.562300662766491 0.914846888547703 0.05046105013377501 0.10280678682718625 0.5036039898143478 0.020488662654551154 0.021806549605331394 2.716849725180657e-07 6.565934382682481 -0.368845638064105 S(ph)PTDDEVTPSAVVR ddPTM_PC-9_AZD4547_30min_R2 2 SPTDDEVTPSAVVR 14 0 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 S(0.982)PT(0.018)DDEVTPSAVVR;S(0.952)PT(0.048)DDEVTPSAVVR 122.97 0.0010244000000000002 0.0 12248.5 12811.1 12354.5 16954.0 16582.6 15421.599999999999 14945.1 12682.8 12936.3 14208.5 True False 16143.268215373153 16952.03754028509 12190.671257713098 13045.517236688876 14280.392226511532 14457.284914107548 16275.184947505011 10722.96468175051 13620.086408020125 13711.06473973081 1.1773898323588614 1.2363764493914797 0.889111931795345 0.9514590941202864 1.0415232148332705 1.0544246700414448 1.1870110204019462 0.782066519653895 0.9933646049057696 1.0 13.743052988236597 -5.24958906620553 24.941509692230674 0.9897631313199217 1.2068831707720593 0.4294682408521765 0.10117321048450881 712.727533535782 1500080.281111823 0.02664122020363248 0.06925841143242484 5.628736700074487e-06 5.24958906620553 0.21712003945213765 S(ph)PTEDFR ddPTM_PC-9_AZD4547_30min_R2 1 SPTEDFR 7 0 Q8IXT5 Q8IXT5 RBM12B RNA-binding protein 12B 1 S(0.999)PT(0.001)EDFR 85.73100000000001 0.019088 54974000.0 138090.0 135640.0 144980.0 132090.0 127980.0 151020.0 130760.0 171700.0 152980.0 133740.0 True False 181999.7475495674 179482.9774152312 143057.470471751 101638.69127015663 110212.18609560309 141576.6955263089 142397.38668431508 145167.71027348528 161066.21048513995 129057.80330728751 1.4102188545408971 1.3907177467439222 1.108475944930894 0.7875439428343144 0.853975375926608 1.0970022106235129 1.103361308151712 1.1248270662707622 1.2480160544933514 1.0 16.977657849130033 -5.307982361600636 4.071553336233159 1.0294264271552962 1.4068564663887673 0.571394251969555 0.12592775185458216 0.16164140490334733 5.753830582651986 0.03764546562387036 0.08975880552478427 4.920595197393592e-06 5.307982361600636 0.37743003923347107 S(ph)PTEDFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPTEDFR 7 0 Q8IXT5 Q8IXT5 RBM12B RNA-binding protein 12B 1 S(0.901)PT(0.099)EDFR;S(0.982)PT(0.018)EDFR 88.37 0.017315999999999998 115720000.0 339700.0 462110.0 435520.0 351300.0 344180.0 293870.0 388940.0 251815.0 274389.0 240065.0 True False 397204.50061916985 507985.2268214032 445904.44851879677 331617.7999299667 276740.39971680276 278458.9398714315 352096.7875182495 245205.12307004715 278401.4200320119 283586.88414650527 1.4006448211263818 1.7912860404325694 1.5723733128942443 1.169369313140194 0.9758575420358104 0.9819175548597495 1.2415834694821464 0.8646560781822705 0.9817147251710892 1.0 18.11343128411452 -5.835497565594116 3.1526411889291035 1.0142872730493662 1.6191551653870397 0.8114409742204808 0.1250313137244224 0.09600587231294062 1.9168773064871127 0.03599044925121672 0.05907385703118974 1.4605029361608402e-06 5.835497565594116 0.6048678923376736 S(ph)PTEDFR ddPTM_PC-9_Lapatinib_30min_R1 3 SPTEDFR 7 0 Q8IXT5 Q8IXT5 RBM12B RNA-binding protein 12B 1 S(0.983)PT(0.017)EDFR;S(0.997)PT(0.003)EDFR;S(0.974)PT(0.026)EDFR 90.601 0.015819 143902100.0 171251.0 205178.0 192694.0 148490.0 190415.0 184443.0 165300.0 185559.0 173889.0 172673.0 True False 168808.9293364127 204702.92294709862 176851.44314035057 159410.44994811923 179215.1640702939 176554.8028476327 173858.42518088833 194180.74855643377 154303.7896876521 202519.29797769035 0.8335449066933305 1.0107823056430347 0.8732572397117071 0.7871370854034858 0.8849288233758165 0.8717924889660742 0.8584783125213118 0.9588259020028049 0.7619214130628199 1.0 17.62769986278068 -11.415719504147464 7.076527879826163 1.021718643431725 0.8755061055813351 0.23483883869307243 0.06936189788773066 0.024148768661079803 0.00036568242653020134 0.06823794848517767 0.015846704907553032 3.8395514883810126e-12 11.415719504147464 -0.1462125378503898 S(ph)PTESVNTPVGK ddPTM_PC-9_AZD4547_30min_R2 2 SPTESVNTPVGK 12 0 Q8WXG6-4;Q8WXG6-7;Q8WXG6-2;Q8WXG6;A0A0A0MRB5;Q8WXG6-6;Q8WXG6-8;Q8WXG6-5;Q8WXG6-3 Q8WXG6-4 MADD MAP kinase-activating death domain protein 1 S(0.869)PT(0.131)ESVNTPVGK;S(0.988)PT(0.012)ESVNTPVGK 128.51 0.00020254 21445900.0 37220.0 33974.0 35307.0 42163.0 42602.0 26453.0 35398.0 42310.0 38074.0 34083.0 True False 49055.18577590634 44955.43110221964 34838.80611081603 32442.9717618564 36687.44766404809 24798.889728231006 38548.35342498762 35771.96168707729 40086.513910388436 32889.764544057805 1.4915031000052916 1.3668517158886666 1.0592598212172475 0.9864154460089581 1.1154670205955128 0.7540002207985226 1.1720471082530797 1.0876320394193946 1.2188142562313011 1.0 15.005351059588497 -5.172030260349179 3.0199580654873723 1.0440576079708757 1.4741547146824616 0.62214707129458 0.12015903254491953 0.17130879308298308 2.9459749397585155 0.032187668374819706 0.11095171490550006 6.7292976690394506e-06 5.172030260349179 0.43009710671158596 S(ph)PTESVNTPVGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPTESVNTPVGK 12 0 Q8WXG6-4;Q8WXG6-7;Q8WXG6-2;Q8WXG6;A0A0A0MRB5;Q8WXG6-6;Q8WXG6-8;Q8WXG6-5;Q8WXG6-3 Q8WXG6-4 MADD MAP kinase-activating death domain protein 1 S(0.999)PT(0.001)ESVNTPVGK;S(1)PTESVNTPVGK;S(0.995)PT(0.005)ESVNTPVGK 160.48 0.00057931 15869100.0 34615.1 58781.0 41038.0 51717.0 46020.0 40534.0 48561.0 44678.0 37179.1 33332.1 True False 40474.75275061119 64616.38920990444 42016.50155748169 48819.46415877624 37002.71135733415 38408.325683971125 43960.95052880583 43505.24984025401 37722.774001553145 39374.945873241566 1.0279316416309547 1.6410534104077705 1.0670872207099407 1.239861111579406 0.9397526913803445 0.9754508820816605 1.1164701196117914 1.1048967528821243 0.9580400217689898 1.0 15.26499031985039 -5.774320957311366 1.7968034320542376 1.0301307940161817 1.3192070271964598 0.2933737724653548 0.16594746898486107 0.39546962413870357 2.6027526792113833 0.049016266861657144 0.1001384483365151 1.6814309712982167e-06 5.774320957311366 0.2890762331802781 S(ph)PTESVNTPVGK ddPTM_PC-9_Lapatinib_30min_R1 2 SPTESVNTPVGK 12 0 Q8WXG6-4;Q8WXG6-7;Q8WXG6-2;Q8WXG6;A0A0A0MRB5;Q8WXG6-6;Q8WXG6-8;Q8WXG6-5;Q8WXG6-3 Q8WXG6-4 MADD MAP kinase-activating death domain protein 1 S(1)PTESVNTPVGK;S(0.998)PT(0.002)ESVNTPVGK 182.72 0.00058043 22401000.0 39145.0 63236.0 42991.0 46880.0 46010.0 50041.0 50509.0 55939.0 45925.0 38407.0 True False 38586.78512168616 63089.58092720827 39456.44593005905 50327.711587095546 43303.782259140404 47900.86308126848 53124.10887756496 58538.13015535955 40752.44288831052 45045.59877588937 0.8566160994698491 1.4005714796042834 0.8759223320875933 1.1172614629341642 0.9613321486652927 1.0633860883853405 1.179340719653162 1.299530514548117 0.9046931108866344 1.0 15.459098532549723 -7.032899676969798 22.19653747452508 1.120925107187293 1.0526792270730811 0.011007598598452795 0.1731817993658054 705.3402691084472 475869.7620955639 0.0628530712662034 0.04875242522823259 9.270439479437566e-08 7.032899676969798 -0.06824588011421184 S(ph)PTFSEELPVLGDGQQLR ddPTM_PC-9_AZD4547_30min_R2 4 SPTFSEELPVLGDGQQLR 18 0 Q8N0Z3 Q8N0Z3 SPICE1 Spindle and centriole-associated protein 1 1 S(0.991)PT(0.008)FS(0.001)EELPVLGDGQQLR;S(0.957)PT(0.043)FSEELPVLGDGQQLR;S(0.835)PT(0.15)FS(0.015)EELPVLGDGQQLR;S(1)PTFSEELPVLGDGQQLR 183.31 1.7266999999999998e-10 34790600.0 16655.87 12995.099999999999 22701.9 31803.33 27861.8 23929.4 15085.279999999999 22793.7 18932.010000000002 26507.28 True False 21952.09019638217 17195.511941968976 22400.857972842063 24471.563625050407 23993.669999675498 22433.09083516921 16427.84069594037 19271.457412118503 19932.717398135563 25579.268195388082 0.8581985234565902 0.6722440927793748 0.8757427226507174 0.9566952204466352 0.9380123706588891 0.8770028393233655 0.6422326303651757 0.7534014368555364 0.7792528404596584 1.0 14.642687369883667 S(ph)PTFSEELPVLGDGQQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SPTFSEELPVLGDGQQLR 18 0 Q8N0Z3 Q8N0Z3 SPICE1 Spindle and centriole-associated protein 1 1 S(1)PTFSEELPVLGDGQQLR;S(0.959)PT(0.04)FS(0.001)EELPVLGDGQQLR;S(0.717)PT(0.234)FS(0.049)EELPVLGDGQQLR;S(0.982)PT(0.017)FS(0.001)EELPVLGDGQQLR;S(0.998)PT(0.002)FSEELPVLGDGQQLR 209.89 1.5572000000000002e-20 22522300.0 7168.990000000001 8396.72 11256.78 11418.099999999999 13441.310000000001 14165.189999999999 13447.850000000002 12072.67 12177.939999999999 9497.800000000001 True False 8382.558412993296 9230.290869610748 11525.184326775885 10778.380874979654 10807.581794751186 13422.34250000817 12173.972293997265 11755.775204551213 12356.019334100994 11219.67595545657 0.7471301708064507 0.8226878304022402 1.0272296965199545 0.9606677517043353 0.9632704043912278 1.1963217612787074 1.0850556060914205 1.0477820617300375 1.1012813010960245 1.0 13.453743388454546 -4.652165372279252 0.6836275176627892 1.0793317374417892 0.4592305179549059 0.7355441752651293 0.06445662134560175 1.8617332579276233 0.5830355792695395 0.02887529939860634 0.9349677232549132 2.2275867589255523e-05 4.652165372279252 -0.6201012194868833 S(ph)PTFSEELPVLGDGQQLR ddPTM_PC-9_Lapatinib_30min_R1 4 SPTFSEELPVLGDGQQLR 18 0 Q8N0Z3 Q8N0Z3 SPICE1 Spindle and centriole-associated protein 1 1 S(1)PTFSEELPVLGDGQQLR;S(0.998)PT(0.002)FSEELPVLGDGQQLR;S(0.985)PT(0.015)FSEELPVLGDGQQLR;S(1)PTFSEELPVLGDGQQLR 245.18 2.1209e-53 30171600.0 13882.8 10758.400000000001 15746.400000000001 16246.6 14744.34 14782.3 11919.6 14086.759999999998 18768.39 10212.630000000001 True False 13684.828726206275 10733.489585794132 14451.791774861762 17441.42916106883 13877.106909687755 14150.095488224355 12536.73856494927 14741.282295845687 16654.496278291525 11977.8694880259 1.1425094203845514 0.8961100800542403 1.2065410955854048 1.456137853105243 1.1585622070402832 1.1813532867735783 1.0466584710646631 1.2307098779613794 1.390438950344281 1.0 13.548083697325389 -5.346520767609073 8.842328897288926 1.217711951227494 1.0197581746719837 0.22244650648316067 0.14098309390454147 0.4699990466393586 45.27052468559048 0.03692904050298085 0.07709803388123958 4.502764489195193e-06 5.346520767609073 -0.19795377655551039 S(ph)PTGASDHFLGR ddPTM_PC-9_AZD4547_30min_R2 1 SPTGASDHFLGR 12 0 F8WBW8;Q9P281 F8WBW8 BAHCC1 BAH and coiled-coil domain-containing protein 1 1 S(1)PTGASDHFLGR 137.81 3.8263e-05 4856300.0 2986.8 6147.2 2848.4 9755.1 7389.3 6733.9 7317.8 7862.5 6952.9 6626.0 True False 3936.5402707006183 8134.162184952158 2810.6283548885026 7506.212409792593 6363.423243602432 6312.828168485037 7969.070023542971 6647.531287275946 7320.416099373323 6394.025756797436 0.6156591200020918 1.272150362595083 0.43957100921912096 1.17394153469163 0.9952138895964768 0.9873010226419439 1.2463306102686744 1.0396472488727482 1.144883736445861 1.0 12.64250884034278 S(ph)PTGNTPPVIDSVSEK ddPTM_PC-9_AZD4547_30min_R2 2 SPTGNTPPVIDSVSEK 16 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 S(0.971)PT(0.029)GNTPPVIDSVSEK;S(0.9)PT(0.1)GNTPPVIDSVSEK 193.27 1.0708e-11 11180900.0 23563.0 28747.0 28398.0 27308.0 31214.0 36198.0 31811.0 41287.0 32185.0 35447.0 True False 31055.543859153167 38038.90557177571 28021.423965076418 21012.562504394224 26880.474892859445 33934.533337712375 34642.11737392734 34907.042830875915 33886.233393020244 34206.01131922708 0.9078972572781953 1.1120532358122144 0.8191958923116438 0.6142944381411444 0.785840671161505 0.992063442329445 1.0127493980701319 1.020494395125654 0.9906514114369397 1.0 15.0619622642614 -6.827304798592985 7.681507753640019 1.0060666160343448 0.8481583259666625 0.31162349272909406 0.11545089877000832 0.3562388671252259 35.72359501988549 0.04669532999371007 0.041284677262748176 1.4883161740369538e-07 6.827304798592985 -0.15790829006768226 S(ph)PTGNTPPVIDSVSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPTGNTPPVIDSVSEK 16 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 S(0.959)PT(0.041)GNTPPVIDSVSEK;S(0.936)PT(0.063)GNT(0.001)PPVIDSVSEK 102.36 0.0015119999999999999 8258500.0 49095.0 57928.0 64844.0 53433.0 59087.0 42422.0 55210.0 45760.0 41833.0 42259.0 True False 57405.81382955005 63678.7090071851 66390.1268822394 50439.322242123344 47509.32650957851 40197.31564033708 49980.10911421449 44558.84848672777 42444.72848473936 49920.222177940035 1.149951088457253 1.275609487077263 1.3299245072586534 1.0103985928254282 0.9517050292811615 0.8052311044821522 1.001199652839304 0.8926011652732292 0.8502511934631547 1.0 15.607336734709126 -5.913582745400356 3.9818746709047663 0.9143452459394755 1.2530811481767585 0.8130907432342149 0.07162994392669784 0.08790702703510356 2.663751340492131 0.020828017077261226 0.03183487704553462 1.2201613233027319e-06 5.913582745400356 0.338735902237283 S(ph)PTGNTPPVIDSVSEK ddPTM_PC-9_Lapatinib_30min_R1 2 SPTGNTPPVIDSVSEK 16 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 S(0.856)PT(0.144)GNTPPVIDSVSEK;S(0.998)PT(0.002)GNTPPVIDSVSEK 216.71 4.4556e-22 9798200.0 45827.0 51850.0 51018.0 46733.0 57810.0 56682.0 54159.0 58390.0 52384.0 52459.0 True False 45173.49857635747 51729.944510654524 46823.49697517512 50169.900716717944 54409.72945883297 54257.84299219556 56963.08801797775 61103.01256317489 46483.962292025215 61526.46825277634 0.7342124431840609 0.8407754577773972 0.761030143690431 0.8154198045400414 0.8843304516569218 0.8818618154593525 0.9258306162471357 0.9931175037081322 0.7555116295811056 1.0 15.908919560769649 -6.304089944220249 1.5816498128704182 0.9140620090877302 0.7818982992646035 0.4359234286300221 0.06784854457416957 0.37370996390006384 1.8614755152643336 0.024100638418987852 0.031575120652642986 4.964894857337966e-07 6.304089944220249 -0.13216370982312664 S(ph)PTGPSNSFLANMGGTVAHK ddPTM_PC-9_AZD4547_30min_R2 11 SPTGPSNSFLANMGGTVAHK 20 0 H0Y6J6;Q5W012;Q96I25 H0Y6J6 RBM17 Splicing factor 45 1 S(0.401)PT(0.401)GPS(0.132)NS(0.065)FLANMGGTVAHK;S(0.463)PT(0.463)GPS(0.046)NS(0.027)FLANMGGT(0.001)VAHK;S(0.692)PT(0.219)GPS(0.071)NS(0.018)FLANMGGTVAHK;S(0.319)PT(0.319)GPS(0.319)NS(0.042)FLANMGGTVAHK;S(0.45)PT(0.45)GPS(0.095)NS(0.004)FLANMGGTVAHK;S(0.456)PT(0.456)GPS(0.087)NSFLANMGGTVAHK;S(0.442)PT(0.442)GPS(0.113)NS(0.003)FLANMGGTVAHK;S(0.837)PT(0.158)GPS(0.005)NSFLANMGGTVAHK;S(0.855)PT(0.121)GPS(0.023)NS(0.001)FLANMGGTVAHK;S(0.612)PT(0.152)GPS(0.187)NS(0.049)FLANMGGTVAHK;S(0.786)PT(0.206)GPS(0.007)NSFLANMGGTVAHK 150.72 7.621699999999999e-06 664407600.0 441820.0 508939.0 709394.0 628654.0 617681.0 783516.0 661154.0 963932.0 706963.0 630241.0 True False 582309.5695731032 673443.5789054153 699986.9720501937 483727.5329074792 531926.6551001576 734522.6206594562 719995.4251749882 814978.4583537653 744331.6208864311 608176.4544204304 0.9574681251480258 1.107316098823954 1.1509603289677752 0.795373660705845 0.8746255321690545 1.207745902230676 1.1838594209654454 1.3400361892181598 1.2238744454448693 1.0 19.214130437881437 -6.7807907054423815 24.521268782255387 1.2119028452794256 0.9839378750523895 0.42180159817029983 0.12393264438524319 193.15065017747582 244751.24424620034 0.04592207242769511 0.04056363381460972 1.656568101997146e-07 6.7807907054423815 -0.2279649702270361 S(ph)PTGPSNSFLANMGGTVAHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 SPTGPSNSFLANMGGTVAHK 20 0 H0Y6J6;Q5W012;Q96I25 H0Y6J6 RBM17 Splicing factor 45 1 S(0.459)PT(0.459)GPS(0.041)NS(0.041)FLANMGGTVAHK;S(0.46)PT(0.237)GPS(0.066)NS(0.237)FLANMGGTVAHK;S(0.756)PT(0.214)GPS(0.018)NS(0.012)FLANMGGTVAHK;S(0.887)PT(0.072)GPS(0.037)NS(0.004)FLANMGGTVAHK;S(0.25)PT(0.25)GPS(0.25)NS(0.25)FLANMGGTVAHK;S(0.792)PT(0.188)GPS(0.012)NS(0.009)FLANMGGTVAHK;S(0.935)PT(0.062)GPS(0.003)NSFLANMGGTVAHK;S(0.484)PT(0.484)GPS(0.032)NSFLANMGGTVAHK 135.68 4.8542e-05 118978100.0 231513.3 374900.0 356907.0 329121.0 362694.0 315543.0 376352.0 290940.9 321172.0 286190.0 True False 270703.9290938948 412117.59437221463 365417.0164573352 310681.41739467875 291626.7143206643 298995.3695982953 340701.21400747704 283304.00965236494 325868.53290227056 338073.981521207 0.8007239358551874 1.2190160050703662 1.0808788502832862 0.9189746457172719 0.8626121211944577 0.8844081057433864 1.0077711762213952 0.8379941229952166 0.9638971074792076 1.0 18.36697946382776 -5.769502638738709 24.65041017676988 0.9174898648470582 1.0520872393647713 0.16302586839287891 0.10927840705769537 204.27109302523843 624484.7213128898 0.029406743099140473 0.04450679706694264 1.700189623394131e-06 5.769502638738709 0.13459737451771314 S(ph)PTGPSNSFLANMGGTVAHK ddPTM_PC-9_Lapatinib_30min_R1 8 SPTGPSNSFLANMGGTVAHK 20 0 H0Y6J6;Q5W012;Q96I25 H0Y6J6 RBM17 Splicing factor 45 1 S(0.807)PT(0.191)GPS(0.002)NSFLANMGGTVAHK;S(0.815)PT(0.062)GPS(0.108)NS(0.014)FLANMGGTVAHK;S(0.326)PT(0.326)GPS(0.326)NS(0.022)FLANMGGTVAHK;S(0.478)PT(0.168)GPS(0.168)NS(0.186)FLANMGGTVAHK;S(0.542)PT(0.146)GPS(0.129)NS(0.183)FLANMGGTVAHK;S(0.99)PT(0.01)GPSNSFLANMGGTVAHK;S(0.749)PT(0.191)GPS(0.05)NS(0.01)FLANMGGTVAHK;S(0.767)PT(0.195)GPS(0.038)NSFLANMGGTVAHK 168.45 2.1321e-08 394668200.0 287429.0 335935.0 350743.0 296163.0 368895.0 370528.0 364583.0 393882.0 383617.0 309865.0 True False 283330.20975197665 335157.16314728465 321906.2644471336 317943.81499080564 347197.32137547503 354681.3811829545 383459.3238216809 412183.19565693586 340410.01379390334 363424.75238084 0.7796117570304328 0.9222188663585215 0.8857576770384687 0.8748545961933435 0.9553485806922696 0.9759417289532244 1.055127151658196 1.1341637930731832 0.9366726167214415 1.0 18.471297157412735 -6.598627161497105 1.372690973110077 1.0406670817374197 0.8653799763339861 0.6151726640029876 0.05815586098456201 0.27137804182271025 1.0631712277404042 0.024950621838537523 0.026016512436654884 2.519839262254806e-07 6.598627161497105 -0.17528710540343362 S(ph)PTKAPHLQLIEGK ddPTM_PC-9_AZD4547_30min_R2 1 SPTKAPHLQLIEGK 14 1 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 S(0.534)PT(0.466)KAPHLQLIEGK 58.711999999999996 0.026262999999999998 23709000.0 79814.0 86496.0 105970.0 101790.0 110190.0 110440.0 110230.0 138840.0 102830.0 89532.0 True False 105193.19176566887 114454.14047853026 104564.76856043206 78323.8881398231 94892.02051785044 103534.16934131611 120040.25645619488 117385.46822580513 108265.38386839427 86397.51193141995 1.2175488554481573 1.324738848606901 1.210275229261611 0.9065525891763471 1.098318902900505 1.1983466540506256 1.3893948306228963 1.3586672301279068 1.2531076584049372 1.0 16.398702145920986 -7.010574205685462 23.027626827464537 1.282137012196629 1.1505267491387632 0.08163268238457155 0.1408779117144667 359.9617410047547 783895.6646362495 0.054205899017421184 0.04483252762293955 9.759460132601229e-08 7.010574205685462 -0.13161026305786572 S(ph)PTKAPHLQLIEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPTKAPHLQLIEGK 14 1 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 S(0.946)PT(0.054)KAPHLQLIEGK 77.192 0.0072741 3838100.0 15759.0 19121.0 17287.0 18873.0 30286.0 18999.0 20841.0 21549.0 21405.0 17775.0 True False 18426.687445562253 21019.20651371333 17699.187641312583 17815.60699709155 24351.675709870116 18002.658994172 18866.78960422648 20983.3615830528 21718.007630718486 20997.466793177417 0.8775671668903188 1.0010353496805136 0.8429201396362477 0.848464587303468 1.1597435038107817 0.8573728998595916 0.8985269408954015 0.9993282422940085 1.034315607908245 1.0 14.357927666232937 -7.403019459257279 0.4351797080711351 1.0167385615307 0.908447700152289 0.11614519708070736 0.09252266197507779 2.7487098436842543 1.2260932908069744 0.1015987112329429 0.09888846125714477 3.9534890543268616e-08 7.403019459257279 -0.10829086137841104 S(ph)PTKAPHLQLIEGK ddPTM_PC-9_Lapatinib_30min_R1 1 SPTKAPHLQLIEGK 14 1 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 S(0.5)PT(0.5)KAPHLQLIEGK 50.843 0.041992 10962000.0 72268.0 71366.0 61324.0 53955.0 65337.0 67710.0 68104.0 67761.0 77817.0 71565.0 True False 71237.44506767187 71200.75641171387 56282.17743748556 57923.0306886037 61494.00611748439 64814.20113971914 71630.0918845687 70909.42343369224 69052.43001066227 83934.9148956317 0.8487224316156344 0.8482853232203543 0.6705454757113801 0.6900945900836106 0.7326391668347874 0.7721959475423538 0.8534004230973088 0.8448143841196966 0.8226901772227332 1.0 16.35698344133082 -8.683015594480196 0.598680393747661 0.9997795322666106 0.7572136793251671 0.5656913702896529 0.06023213356911576 0.8612168670175712 0.6809845072693019 0.07392102686454559 0.030043467086213745 2.0748390135913417e-09 8.683015594480196 -0.2425658529414435 S(ph)PTLGIAR ddPTM_PC-9_AZD4547_30min_R2 1 SPTLGIAR 8 0 Q99618;F5GX58;F8WDL1;J3KMY0 Q99618 CDCA3 Cell division cycle-associated protein 3 1 S(0.999)PT(0.001)LGIAR 99.01299999999999 0.0053299 12770000.0 3704.3 9958.6 12758.0 10810.0 15648.0 13750.0 16275.0 14408.0 20991.0 10885.0 True False 4882.190345773506 13177.522698962866 12588.820584070885 8317.921512835132 13475.54530414123 12890.210326359062 17723.443471147326 12181.574662902625 22100.54140602418 10503.919463136142 0.4647970086697367 1.254533866639955 1.1984879195096434 0.7918874037474446 1.282906380940382 1.2271809938754468 1.6873171517878012 1.1597170661536649 2.1040280710059487 1.0 13.358640139337334 -6.704682265931268 1.4832727051671144 1.5010342919560289 0.965904950950341 0.31500897115715143 0.3522212805270906 0.48718335404209256 2.2309910529237986 0.14756729245632005 0.1402373075215916 1.973866307781809e-07 6.704682265931268 -0.5351293410056879 S(ph)PTLGIAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPTLGIAR 8 0 Q99618;F5GX58;F8WDL1;J3KMY0 Q99618 CDCA3 Cell division cycle-associated protein 3 1 S(0.99)PT(0.01)LGIAR;S(0.997)PT(0.003)LGIAR 89.029 0.010532 22118000.0 14612.1 18298.4 18868.6 14049.900000000001 19794.3 15575.6 21542.3 11030.5 9960.0 10862.8 True False 17085.63992786981 20114.944222087346 19318.498983563986 13262.72965339038 15915.749009571486 14758.78811672327 19501.657391254175 10740.961062780822 10105.646157531233 12832.139650122519 1.3314724117506531 1.5675440550473818 1.5054776140454127 1.0335555889359223 1.2403036004536878 1.1501424173311858 1.5197510253925561 0.8370358611767655 0.7875261985194142 1.0 13.647474127159636 -6.989231656861956 0.45701106516387274 0.8774124269716929 1.4843167106478414 0.43975436205049556 0.20105829793778904 1.1150865152988936 0.5041490143700919 0.20982913293436267 0.25554674775102276 1.025104979516005e-07 6.989231656861956 0.6069042836761486 S(ph)PTLGIAR ddPTM_PC-9_Lapatinib_30min_R1 2 SPTLGIAR 8 0 Q99618;F5GX58;F8WDL1;J3KMY0 Q99618 CDCA3 Cell division cycle-associated protein 3 1 S(0.998)PT(0.002)LGIAR;S(0.999)PT(0.001)LGIAR 97.965 0.0056512 34970000.0 21753.0 29013.0 18712.2 16465.0 20631.4 17429.2 22780.0 26389.0 16481.6 17221.7 True False 21442.798230988377 28945.8221810534 17173.75514718083 17675.891025629862 19417.901614893053 16683.793745449613 23959.436936603965 27615.129277780823 14625.268649057783 20198.4478985272 1.0616062352272082 1.4330716066140918 0.8502512288794764 0.8751113508537816 0.9613561256015587 0.8259938500851908 1.1862018832818835 1.36719065823837 0.7240788362814852 1.0 14.30195681633202 -5.268263027709067 24.963085799959885 0.9852287758591426 1.2473389227094343 0.23802175333837616 0.19492724586781468 717.5093786109544 2624886.8498813366 0.05201234725734429 0.11218680047180855 5.3918397024268775e-06 5.268263027709067 0.26211014685029166 S(ph)PTLSQVHSPLVT(ph)SPSANLK ddPTM_PC-9_Lapatinib_30min_R1 1 SPTLSQVHSPLVTSPSANLK 20 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 2 S(0.716)PT(0.274)LS(0.009)QVHSPLVT(0.831)S(0.146)PS(0.023)ANLK 101.58 0.0010159 0.0 9344.1 10983.0 12621.0 6030.7 10298.0 12201.0 9579.5 11170.0 13043.0 9861.5 True False 9210.851420501922 10957.56953829351 11583.35009846888 6474.217795825448 9692.291886646986 11679.191671920153 10075.479637146515 11688.998978089816 11573.959991121052 11566.04713537722 0.7963698671371112 0.9473910498581187 1.0014960135376534 0.5597606269494332 0.837995191719481 1.00978247237095 0.8711255902051889 1.01063041169325 1.0006841452097865 1.0 13.497608266243665 -6.748459264901225 22.12661151191957 0.9724014439587544 0.8298712487774136 0.2975070958839815 0.11493095458096039 84.7885418862301 144533.4113027136 0.039991193388759255 0.03966055303022262 1.7845993690285293e-07 6.748459264901225 -0.1425301951813408 S(ph)PTMEQAVQTASAHLPAPAAVGR ddPTM_PC-9_AZD4547_30min_R2 10 SPTMEQAVQTASAHLPAPAAVGR 23 0 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 1 S(0.984)PT(0.016)MEQAVQTASAHLPAPAAVGR;S(0.5)PT(0.5)MEQAVQTASAHLPAPAAVGR;S(0.889)PT(0.111)MEQAVQTASAHLPAPAAVGR;S(0.5)PT(0.5)MEQAVQTASAHLPAPAAVGR;S(0.867)PT(0.133)MEQAVQTASAHLPAPAAVGR;S(0.853)PT(0.147)MEQAVQTASAHLPAPAAVGR;S(0.5)PT(0.5)MEQAVQTASAHLPAPAAVGR;S(0.868)PT(0.132)MEQAVQTASAHLPAPAAVGR;S(0.694)PT(0.306)MEQAVQTASAHLPAPAAVGR;S(0.804)PT(0.196)MEQAVQTASAHLPAPAAVGR 171.13 2.0411000000000003e-10 252730000.0 64608.59999999999 58269.0 154138.7 180978.3 152696.3 155794.6 116516.3 205845.4 146870.40000000002 145222.3 True False 85152.79085763636 77103.31473760036 152094.7201255627 139256.54902186195 131497.05447499634 146052.7390335259 126886.02497801783 174036.72328671932 154633.66950213563 140138.11147922798 0.6076347822787533 0.550195189044124 1.085320178216523 0.9937093311158492 0.9383389934899153 1.042205703301308 0.9054355281277324 1.2418943101892448 1.103437657821272 1.0 17.096489833952 -5.25999880882945 24.999999987585525 1.0375931842007327 0.5789149425287718 0.8074698613349973 0.08982167893483682 51.24034052768898 889215.0111873054 0.02432025327171106 0.05767702258790355 5.495423811247668e-06 5.25999880882945 -0.4586782416719608 S(ph)PTMEQAVQTASAHLPAPAAVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SPTMEQAVQTASAHLPAPAAVGR 23 0 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 1 S(0.592)PT(0.407)MEQAVQTAS(0.001)AHLPAPAAVGR;S(0.5)PT(0.5)MEQAVQTASAHLPAPAAVGR;S(0.825)PT(0.175)MEQAVQTASAHLPAPAAVGR;S(0.5)PT(0.5)MEQAVQTASAHLPAPAAVGR;S(0.745)PT(0.254)MEQAVQTASAHLPAPAAVGR;S(0.828)PT(0.172)MEQAVQTASAHLPAPAAVGR 92.805 9.4838e-06 198418000.0 45264.0 44061.799999999996 80347.0 75522.5 82074.1 57848.7 73146.3 68156.5 55247.799999999996 58313.99999999999 True False 52926.301195249034 48435.96430970841 82262.77719769446 71291.21917224851 65992.26927885647 54815.01233518386 66217.3529306479 66367.46409278097 56055.69455643114 68885.86658662988 0.7683187251290462 0.7031335556880313 1.194189479989222 1.0349179404253221 0.9579943252345609 0.7957367026260646 0.9612618119186161 0.9634409405203344 0.8137473960051921 1.0 16.07192039300179 -5.210344458340476 24.99966012966751 0.9599008651937264 0.7357258528044623 0.42731617325267146 0.10610373254022686 355.72483666062186 174047.29212897504 0.02825230021802175 0.07474835607122192 6.161061467327835e-06 5.210344458340476 -0.22417501238926407 S(ph)PTMEQAVQTASAHLPAPAAVGR ddPTM_PC-9_Lapatinib_30min_R1 11 SPTMEQAVQTASAHLPAPAAVGR 23 0 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 1 S(0.499)PT(0.499)MEQAVQT(0.001)AS(0.001)AHLPAPAAVGR;S(0.5)PT(0.5)MEQAVQTASAHLPAPAAVGR;S(0.798)PT(0.202)MEQAVQTASAHLPAPAAVGR;S(0.548)PT(0.452)MEQAVQTASAHLPAPAAVGR;S(0.856)PT(0.144)MEQAVQTASAHLPAPAAVGR;S(0.5)PT(0.5)MEQAVQTASAHLPAPAAVGR;S(0.5)PT(0.5)MEQAVQTASAHLPAPAAVGR;S(0.608)PT(0.392)MEQAVQTASAHLPAPAAVGR;S(0.641)PT(0.359)MEQAVQTASAHLPAPAAVGR;S(0.894)PT(0.106)MEQAVQTASAHLPAPAAVGR;S(0.748)PT(0.252)MEQAVQTASAHLPAPAAVGR 98.76 4.7951e-06 167458300.0 109791.79999999999 100229.4 136229.0 95695.7 127318.90000000001 125518.70000000001 108103.69999999998 117788.90000000001 142082.6 90641.5 True False 108226.14879864962 99997.32498237601 125028.77747914693 102733.48100949678 119830.25262058819 120150.55779938064 113700.78063053347 123261.80230352066 126079.76139189267 106308.76250279327 1.0180360136898967 0.9406310696143093 1.176090987568986 0.9663688918098116 1.1271907394975051 1.1302037101243059 1.0695334792138698 1.1594698254556575 1.1859771332450597 1.0 16.697900990386906 -5.2376343293782135 0.6760548424232331 1.1189778794613232 0.9445502458561101 0.2083779665072243 0.07661102195736749 2.736211218090849 1.4140147662989835 0.03588041210001794 0.33527822141215846 5.785830021563507e-06 5.2376343293782135 -0.17442763360521307 S(ph)PTNSLLK ddPTM_PC-9_AZD4547_30min_R2 3 SPTNSLLK 8 0 Q14106-2;Q14106 Q14106-2 TOB2 Protein Tob2 1 S(0.989)PT(0.009)NS(0.002)LLK;S(0.999)PT(0.001)NSLLK;S(0.994)PT(0.006)NSLLK 93.374 0.0072727 39714600.0 138695.0 122555.0 187418.0 219800.0 212166.0 186089.0 169687.0 192934.0 177720.0 184851.0 True False 182797.12496478573 162168.50705635274 184932.7148632544 169128.50587614824 182710.41315174024 174452.82541249722 184788.81427272395 163120.4834822635 187113.91637742918 178379.42275426578 1.0247657613322685 0.9091211561983521 1.0367379376376635 0.9481391029566144 1.0242796524991609 0.9779873862066601 1.0359312269290595 0.914457962491431 1.0489658139279663 1.0 17.444589674882316 -5.284116424162877 24.99636814089528 0.9950104439677908 0.9669434098964517 0.061055760108838064 0.047823328922381766 2116.2207701027824 2332657.5280247787 0.01141083941540326 0.023781001535412686 5.198566164880555e-06 5.284116424162877 -0.028067034071339148 S(ph)PTNSLLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPTNSLLK 8 0 Q14106-2;Q14106 Q14106-2 TOB2 Protein Tob2 1 S(0.998)PT(0.002)NSLLK;S(0.999)PT(0.001)NSLLK;S(0.996)PT(0.003)NSLLK;S(0.999)PT(0.001)NSLLK 88.49600000000001 0.010931999999999999 42017700.0 180727.0 185161.0 184449.0 226358.0 244477.0 230247.0 225725.0 213282.0 190648.0 180905.0 True False 211320.51157904253 203542.5603935821 188846.96368672786 213675.89512253756 196573.48684282906 218172.44199332158 204342.69389252033 207683.57349095904 193435.86632941948 213701.6444568079 0.9888576763935636 0.9524613669256107 0.8836944805302913 0.9998795080199977 0.9198501365887211 1.0209207446572424 0.9562055285626071 0.9718389112954852 0.9051678887221459 1.0 17.705238484168525 S(ph)PTNSLLK ddPTM_PC-9_Lapatinib_30min_R1 4 SPTNSLLK 8 0 Q14106-2;Q14106 Q14106-2 TOB2 Protein Tob2 1 S(0.997)PT(0.003)NSLLK;S(0.999)PT(0.001)NSLLK;S(0.997)PT(0.003)NSLLK;S(1)PTNSLLK 83.499 0.014968 45356000.0 187239.0 174679.0 187904.0 161778.0 182144.0 172141.0 149961.0 152576.0 165427.0 128781.0 True False 184568.9375245723 174274.54150774545 172455.25845041595 173675.69379558729 171430.6480288819 164778.93071027042 157725.24681519147 159665.23796607283 146794.86923646255 151040.62426010388 1.2219820887838098 1.1538256171904515 1.1417806255450478 1.1498608049745878 1.1349969511094233 1.090957691134195 1.0442571168374948 1.0571012848246488 0.9718899796366717 1.0 17.204577107008042 -7.0636522580535335 0.5729608537863272 0.9842445773942948 1.1872953393051922 0.9005087296306039 0.02329936769707296 0.24960364355799305 0.17289074314206565 0.02052754633444817 0.01852502563171821 8.63669816083572e-08 7.0636522580535335 0.20305076191089733 S(ph)PTPESSTIASYVTLR ddPTM_PC-9_AZD4547_30min_R2 4 SPTPESSTIASYVTLR 16 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;H0YGJ6 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 S(0.986)PT(0.008)PES(0.001)ST(0.004)IASYVTLR;S(0.989)PT(0.011)PESSTIASYVTLR;S(0.997)PT(0.003)PESSTIASYVTLR;S(0.995)PT(0.005)PESSTIASYVTLR 202.32 7.474e-13 51461600.0 12486.0 11126.8 20302.6 22655.6 22139.399999999998 22279.3 19436.8 23850.1 14900.3 15192.3 True False 16456.288275066265 14723.320503566774 20033.374258516826 17432.701445530765 19065.726463861465 20886.171849021925 21166.63754592912 20164.615065775524 15687.899438434657 14660.422201176221 1.1224975685724767 1.0042903472715476 1.3664936782591108 1.18909955022524 1.3004895904247424 1.4246637349466105 1.4437945412125237 1.3754457265328754 1.0700851055419127 1.0 13.839639031368538 -5.2594864292518935 24.99924762371117 1.2944181775336123 1.0633939461900213 0.23926676251914847 0.14358283381628575 206.8639259059063 2647963.4491445874 0.03646565272396228 0.08699830030468837 5.501911125052133e-06 5.2594864292518935 -0.23102423134359107 S(ph)PTPESSTIASYVTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPTPESSTIASYVTLR 16 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;H0YGJ6 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 S(1)PTPESSTIASYVTLR;S(0.999)PT(0.001)PESSTIASYVTLR;S(0.999)PT(0.001)PESSTIASYVTLR 195.6 8.1416e-12 37785700.0 12565.3 22679.0 31098.0 20127.2 27620.2 12947.8 15894.599999999999 14861.400000000001 9267.5 14384.6 True False 14692.357114012528 24930.421239710508 31839.494259821746 18999.538237262823 22208.22008326469 12268.794574700778 14388.948421061275 14471.30399695489 9403.019655112525 16992.41411156906 0.8646421289844525 1.4671500515478233 1.8737475470389016 1.1181188330578193 1.3069490854830634 0.7220159827877388 0.8467865911568592 0.8516331994935489 0.5533657309299331 1.0 14.052603210257256 -6.728054221852201 6.399129395227889 0.7882900866071834 1.3562524092075083 0.5033299022659927 0.26311460468630327 0.15144565097572055 18.023457067784054 0.09044627081304382 0.0885420079077083 1.8704485994779597e-07 6.728054221852201 0.567962322600325 S(ph)PTPESSTIASYVTLR ddPTM_PC-9_Lapatinib_30min_R1 4 SPTPESSTIASYVTLR 16 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;H0YGJ6 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 S(0.973)PT(0.022)PES(0.002)S(0.001)T(0.001)IASYVTLR;S(1)PTPESSTIASYVTLR;S(0.995)PT(0.005)PESSTIASYVTLR;S(0.999)PT(0.001)PESSTIASYVTLR 195.5 8.2563e-12 51219600.0 9743.699999999999 21046.100000000002 22667.4 22248.9 16034.8 21420.5 20873.5 12560.400000000001 13410.5 20317.800000000003 True False 9604.753051224252 20997.369048518543 20803.77387069436 23885.158326154655 15091.664589629732 20504.39514862436 21954.227695180107 13144.00203799456 11900.068271174488 23829.704658233273 0.4030579979473546 0.8811426473665445 0.8730185358594682 1.0023270816284424 0.6333131193220849 0.8604552780951062 0.9212966761463751 0.5515805683077674 0.49937959541865157 1.0 14.540473450643615 -7.766185257036105 24.999258388743733 0.6441100775289736 0.8066957945254343 0.04888040033847785 0.20331931552998084 269.94170437791854 1421900.6519883121 0.10371031782332409 0.05238017325484182 1.7132263405014196e-08 7.766185257036105 0.16258571699646063 S(ph)PTPPLFSLPEAR ddPTM_PC-9_AZD4547_30min_R2 2 SPTPPLFSLPEAR 13 0 A0A087WWS1;Q96FV9;J3KRD7;J3QQZ3;J3KT14;Q96FV9-2 A0A087WWS1 THOC1 THO complex subunit 1 1 S(0.958)PT(0.042)PPLFSLPEAR;S(0.992)PT(0.008)PPLFSLPEAR 107.65 0.00098494 5103500.0 8903.9 7977.4 14135.599999999999 13147.400000000001 13069.3 12768.900000000001 13611.900000000001 12353.099999999999 13898.7 13899.7 True False 11735.154987374855 10555.938543440483 13948.152707963027 10116.47005530514 11254.853287539172 11970.458664454265 14823.332730255635 10444.212240998213 14633.356907241581 13413.075733739413 0.8749041025583792 0.7869886633747953 1.039892190638846 0.7542244788686349 0.8390956340631536 0.8924469601214304 1.1051404632696469 0.7786590076969978 1.0909769837825234 1.0 13.711352477120938 -7.017517757119879 24.133967482995327 0.9786125685530984 0.8598981392829851 0.2522769692632214 0.10890932675371712 739.8668527730086 1019302.4642032776 0.03902435796206038 0.0309507169050994 9.604665467197083e-08 7.017517757119879 -0.11871442927011333 S(ph)PTPPLFSLPEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPTPPLFSLPEAR 13 0 A0A087WWS1;Q96FV9;J3KRD7;J3QQZ3;J3KT14;Q96FV9-2 A0A087WWS1 THOC1 THO complex subunit 1 1 S(0.995)PT(0.005)PPLFSLPEAR;S(0.995)PT(0.005)PPLFSLPEAR 101.38 0.0020169 4666400.0 17283.8 16550.1 20127.7 19731.1 18358.1 17515.2 18674.1 14787.2 16324.8 10071.77 True False 20209.605969389497 18193.08455219953 20607.620702727338 18625.630436089305 14760.962089723527 16596.67207825261 16905.15405922391 14399.051668333484 16563.51931651264 11897.702172912548 1.6986142093387266 1.5291259007659188 1.7320672851976937 1.5654813144082733 1.2406565465497827 1.394947682926388 1.420875545003287 1.2102380324425794 1.3921611985062745 1.0 13.538395349398153 -1.5228787452810006 0.07883206275076556 0.6176136106355169 3.5179758615808683 0.7422409285858548 0.10912919399607031 103.07500675110973 0.5956022649032076 3.366399319952765 32.62517642691274 0.029999999999954195 1.5228787452810006 2.9003622509453515 S(ph)PTPPLFSLPEAR ddPTM_PC-9_Lapatinib_30min_R1 2 SPTPPLFSLPEAR 13 0 A0A087WWS1;Q96FV9;J3KRD7;J3QQZ3;J3KT14;Q96FV9-2 A0A087WWS1 THOC1 THO complex subunit 1 1 S(0.995)PT(0.005)PPLFSLPEAR;S(0.984)PT(0.016)PPLFSLPEAR 129.76 8.877100000000001e-05 4056700.0 6519.799999999999 8279.9 7774.700000000001 6056.6 7483.1 8304.2 7772.8 6846.1 8796.0 6734.5 True False 6426.826456415109 8260.72840026554 7135.494177209889 6502.022568225321 7042.958770340657 7949.048724035685 8175.237551397508 7164.1947989167975 7805.301854013711 7898.549351842812 0.8136717478274241 1.0458538691460133 0.9033929977971342 0.8231919911607988 0.8916775038820848 1.0063934996090251 1.0350302552063109 0.9070266551218443 0.9881943514339953 1.0 12.9473719968029 -6.755921325369213 24.983026317520334 0.9844994526610102 0.9003223879019662 0.3220004334774276 0.06633978916184974 189.36412895114384 857347.1985513703 0.022794878863741316 0.022182694315683513 1.754198254900692e-07 6.755921325369213 -0.08417706475904407 S(ph)PTPPPTLHLVPEPAAPPPPPPR ddPTM_PC-9_AZD4547_30min_R2 2 SPTPPPTLHLVPEPAAPPPPPPR 23 0 A0A087WWH3;Q9NZM4-2;Q9NZM4 A0A087WWH3 GLTSCR1 Glioma tumor suppressor candidate region gene 1 protein 1 S(0.395)PT(0.395)PPPT(0.21)LHLVPEPAAPPPPPPR;S(0.491)PT(0.491)PPPT(0.017)LHLVPEPAAPPPPPPR 104.06 1.5893e-06 13286500.0 12870.7 12834.9 20441.8 20445.9 18922.3 22936.2 21038.3 25230.0 18746.3 17198.0 True False 16963.314872809176 16983.530424850727 20170.728375565148 15732.413641006086 16295.265267673287 21501.995788177206 22910.667943412514 21331.283227723015 19737.19114667003 16595.9032546638 1.0221386936587573 1.023356798617032 1.2154040708749458 0.9479697127413022 0.9818848072095124 1.2956206997732822 1.3805014160331484 1.2853342719823624 1.1892809233582065 1.0 14.018539531747308 -6.765010043166978 24.99831737110719 1.257377999547776 1.0421662595342278 0.40181097764652807 0.11469838960659909 85.45277567265802 598252.7241029276 0.03937766927394046 0.036091491859982346 1.717868660561897e-07 6.765010043166978 -0.21521174001354826 S(ph)PTPPPTLHLVPEPAAPPPPPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPTPPPTLHLVPEPAAPPPPPPR 23 0 A0A087WWH3;Q9NZM4-2;Q9NZM4 A0A087WWH3 GLTSCR1 Glioma tumor suppressor candidate region gene 1 protein 1 S(0.478)PT(0.478)PPPT(0.043)LHLVPEPAAPPPPPPR 92.932 7.558200000000001e-06 5510400.0 6536.2 7626.4 8465.7 9576.1 9929.2 6725.4 10118.0 8703.5 5548.6 7687.9 True False 7642.649564165496 8383.498590878267 8667.554394346038 9039.582163135086 7983.644537358594 6372.7081846099445 9159.54979202358 8475.042347120514 5629.737778080104 9081.655412617085 0.8415480677176556 0.9231244976803598 0.9544024740582274 0.9953672268358095 0.8790957347123046 0.7017121763677999 1.0085771124170024 0.9332045714205576 0.619902156853336 1.0 13.148739581946266 -6.512312103723147 24.768254229671765 0.850709882512575 0.9309573036147774 0.0826730703421249 0.11926490529731366 1197.9440002151368 2807992.129304895 0.037904198449250734 0.04033543394302615 3.073886986111847e-07 6.512312103723147 0.0802474211022024 S(ph)PTPPPTLHLVPEPAAPPPPPPR ddPTM_PC-9_Lapatinib_30min_R1 1 SPTPPPTLHLVPEPAAPPPPPPR 23 0 A0A087WWH3;Q9NZM4-2;Q9NZM4 A0A087WWH3 GLTSCR1 Glioma tumor suppressor candidate region gene 1 protein 1 S(0.789)PT(0.208)PPPT(0.004)LHLVPEPAAPPPPPPR 89.92299999999999 1.2142e-05 6908400.0 9502.7 18804.0 21138.0 15325.0 22003.0 21419.0 22671.0 21872.0 22830.0 18675.0 True False 9367.189755418247 18760.460493314313 19400.115235039622 16452.051622701354 20708.826799562386 20502.959300127684 23844.79344994506 22888.252967661632 20258.644989442117 21902.94886712665 0.4276679734881327 0.8565266990816571 0.8857307457881417 0.751134092605843 0.9454812192272211 0.936082142386765 1.0886567646483827 1.0449849975230407 0.9249277397459293 1.0 14.418837497301954 -4.375948259976122 0.6325338285632431 0.9953933204090977 1.5641139904455339e-31 0.7338259848822462 0.09171628977983767 3.1064687662396095 0.6523429564165266 0.04415068514064956 2.5104549097289928 4.2077675497701154e-05 4.375948259976122 -0.9953933204090977 down S(ph)PTQHCLAR ddPTM_PC-9_Lapatinib_30min_R1 2 SPTQHCLAR 9 0 O75161;O75161-2 O75161 NPHP4 Nephrocystin-4 1 S(0.999)PT(0.001)QHCLAR;S(0.993)PT(0.007)QHCLAR 95.477 0.0034734 0.0 8083.4 8396.7 11578.7 7999.2 11473.7 10466.9 11976.2 9979.3 13296.7 10808.5 True False 7968.1292336859915 8377.257957041715 10626.74398107453 8587.487852548951 10798.839524162111 10019.25508653562 12596.269036003358 10442.974709225753 11799.085625541617 12676.734823579045 0.6285632179404014 0.6608372008744559 0.8382871558777517 0.6774211160886641 0.8518628554157336 0.7903655969752995 0.9936524831752401 0.823790578138588 0.9307669356303818 1.0 13.629895574518477 -3.3393481040458717 0.18857122808733143 1.0199071917754752 3.594111022581241e-12 0.7163670497777086 0.06723377767812196 14.890001416744077 0.31412314295511057 0.14641402082434557 3.8654991824690614 0.00045777481516996743 3.3393481040458717 -1.0199071917718812 S(ph)PTSAPTQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPTSAPTQR 9 0 H0YID7;F8VV64;Q63HR2-5;Q63HR2-2;Q63HR2-6;Q63HR2;Q63HR2-4 H0YID7 TNS2 Tensin-2 1 S(0.973)PT(0.025)S(0.002)APTQR 86.344 0.011734999999999999 1915200.0 3420.0 1603.5 4354.7 5418.8 3726.0 4238.2 3150.6 5025.7 3836.1 4193.7 True False 3998.9384519209943 1762.6848828376837 4458.532563291718 5115.2022039866315 2995.917047314802 4015.9413310753066 2852.1523596313023 4893.78070016931 3892.195705311803 4953.984612689063 0.8072165669788663 0.35581153771103136 0.8999891828229943 1.0325430141394925 0.6047489609961856 0.8106487292651119 0.5757289500508017 0.9878473759555999 0.7856697203585151 1.0 12.274373672174168 -14.52287864679158 0.038764138902822695 2.172553644989954 0.06959441134256522 0.14937831975271787 0.18979969491338272 1743.9065860345474 5.0362142786766455 242.03203258583844 75.24165060711093 3.0000006803363073e-15 14.52287864679158 -2.102959233647389 S(ph)PTSAPTQR ddPTM_PC-9_Lapatinib_30min_R1 1 SPTSAPTQR 9 0 H0YID7;F8VV64;Q63HR2-5;Q63HR2-2;Q63HR2-6;Q63HR2;Q63HR2-4 H0YID7 TNS2 Tensin-2 1 S(0.991)PT(0.007)S(0.002)APTQR 90.82700000000001 0.0082729 2418800.0 5774.8 3944.1 5453.7 3746.8 5622.9 5633.7 4297.8 4802.2 6718.6 4557.3 True False 5692.4502930313765 3934.9676787747835 5005.317837890797 4022.3521709583974 5292.172077046739 5392.759783796129 4520.319054703093 5025.327743293006 5961.880518005513 5345.023232779458 1.0650001029221445 0.7361928110326597 0.9364445428776907 0.752541569191036 0.9901120811957189 1.0089310277874783 0.8457061565198263 0.9401881945945804 1.1154077837198257 1.0 12.383980503467136 -8.098611769102197 5.332506288620661 1.0546234981029075 0.9005512730663456 0.2519630044495247 0.10336398768127679 0.29862219183631306 12.632978260566885 0.07000140769450969 0.02560228920032818 7.968713830777346e-09 8.098611769102197 -0.15407222503656182 S(ph)PTSSPTPQR ddPTM_PC-9_AZD4547_30min_R2 1 SPTSSPTPQR 10 0 A0A0D9SFE4;A0A0D9SFB1;A0A0U1RQP1;Q05193-5;Q05193-3;Q05193-2;Q05193 A0A0D9SFE4 DNM1 Dynamin-1 1 S(0.972)PT(0.026)S(0.001)SPTPQR 81.625 0.016028999999999998 24770000.0 7294.3 7568.9 6024.6 8908.4 8563.1 6704.5 6077.1 5855.1 4303.1 6602.2 True False 9613.735669134694 10015.398907093371 5944.709867596287 6854.706013407995 7374.261374865275 6285.266555132676 6617.950127097352 4950.328831812963 4530.553081047237 6371.0589875532805 1.5089698098724902 1.5720147822614416 0.9330803370695635 1.0759131294812343 1.157462423322698 0.9865340389112374 1.0387519782859345 0.7770025111184962 0.711114602752585 1.0 12.637317479609989 -2.450622583241571 0.3711215479284518 0.8562864589137447 5.891799661454968 0.6854480232914699 0.14820267655740368 18.911742141846617 0.5013565677820241 0.12243879248383072 60.61244203395541 0.0035430511059192913 2.450622583241571 5.035513202541223 S(ph)PTSSPTPQR ddPTM_PC-9_Lapatinib_30min_R1 1 SPTSSPTPQR 10 0 A0A0D9SFE4;A0A0D9SFB1;A0A0U1RQP1;Q05193-5;Q05193-3;Q05193-2;Q05193 A0A0D9SFE4 DNM1 Dynamin-1 1 S(0.996)PT(0.003)S(0.001)SPTPQR 73.632 0.02745 20668000.0 5505.1 2261.0 2036.4 2371.5 2527.7 2707.7 2314.2 5877.7 5714.4 1675.2 True False 5426.596264488305 2255.764793415427 1868.9750527313226 2545.9080210920865 2379.025655649406 2591.8979829569867 2434.017952532436 6150.799399598787 5070.784096700312 1964.756087936309 2.7619694362103524 1.1481144185102286 0.9512504194321696 1.2957883356229694 1.2108503799818873 1.3191958018969159 1.2388397559765387 3.1305664033133542 2.580872062356826 1.0 10.940134506781439 -7.737702980810968 24.98826036196001 2.3917897591593076 1.3732007240214417 0.21863252310057557 0.6877010635180812 257.6370953103401 271225.3410328483 0.31314741866832085 0.18066633338737467 1.829350903370379e-08 7.737702980810968 -1.018589035137866 S(ph)PTVEPSTLPR ddPTM_PC-9_AZD4547_30min_R2 3 SPTVEPSTLPR 11 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 S(0.997)PT(0.003)VEPSTLPR;S(1)PTVEPSTLPR;S(0.999)PT(0.001)VEPSTLPR 161.93 0.0012312999999999998 76956400.0 14479.5 19303.7 35792.9 45028.8 41493.0 49684.5 35157.4 43576.3 25145.4 39832.9 True False 19083.679807690372 25543.243520572127 35318.262759334604 34648.105848025 35732.41317131469 46577.72036072632 38286.34049109157 36842.58411875647 26474.534508648463 38438.36229519117 0.49647484097099104 0.664524761081398 0.9188284997187067 0.9013939142865005 0.9296029028735441 1.2117509066340588 0.9960450499183048 0.9584847511405465 0.6887529261869869 1.0 15.230259249507673 -5.0255424260751695 1.4479066557323654 0.9691204679012709 0.4092494023655888 0.617366814333432 0.12034248318337835 0.5222025137058093 1.3962584381356078 0.03723940447704566 0.37261489304178297 9.4288249710119e-06 5.0255424260751695 -0.5598710655356821 S(ph)PTVEPSTLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPTVEPSTLPR 11 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 S(0.976)PT(0.024)VEPSTLPR;S(0.993)PT(0.007)VEPSTLPR;S(0.887)PT(0.108)VEPS(0.002)T(0.002)LPR;S(0.933)PT(0.067)VEPSTLPR 126.71 0.00039703 92548000.0 27453.2 27985.3 57099.6 38316.2 58057.6 48363.2 34416.0 33729.8 42055.899999999994 26866.1 True False 32100.484534584037 30763.4956355955 58461.07101543891 36169.46753679645 46681.630049968815 45826.948653452266 31155.86732973748 32844.42848967723 42670.887975554004 31736.71125806943 1.011462223465959 0.9693347047033275 1.8420645586134732 1.13967283007624 1.4709031969435542 1.443972826321134 0.9816980428876586 1.0349033402547705 1.3445277183439865 1.0 14.953865015047697 -7.263248934816209 24.996343375115405 1.0931908877203198 1.3206457413192103 0.1544286662082781 0.25477684558188696 331.3145890931453 4576565.380254278 0.10501080564060092 0.07492966872286057 5.454451258173096e-08 7.263248934816209 0.2274548535988905 S(ph)PTVLCQK ddPTM_PC-9_AZD4547_30min_R2 2 SPTVLCQK 8 0 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 S(0.997)PT(0.003)VLCQK;S(1)PTVLCQK 89.88600000000001 0.009889299999999998 20330200.0 55046.0 75844.0 78199.0 77253.0 63429.0 78839.0 69636.0 101097.0 92480.0 62904.0 True False 72549.48297207264 100359.08978974348 77162.03016568115 59443.514396952036 54622.97821423659 73909.184866896 75833.46909719313 85474.78162794757 97368.303998338 60701.75010648744 1.1951794280198025 1.6533146015343254 1.271166482520156 0.9792718380058546 0.8998583750618883 1.2175791428952067 1.2492797812939582 1.4081106636629335 1.6040444275087196 1.0 15.889450491311338 -5.509255561368114 24.65167026377454 1.1961422685232723 1.4337454323431105 0.14386662338402967 0.2220385065338746 1002.3031202617311 1813701.964274327 0.06294376667540576 0.1226218809199189 3.0955971534402994e-06 5.509255561368114 0.23760316381983815 S(ph)PTVLCQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPTVLCQK 8 0 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 S(0.998)PT(0.002)VLCQK;S(0.999)PT(0.001)VLCQK 89.08 0.010494 12835100.0 74579.0 91192.0 81777.0 81250.0 93792.0 60362.0 79575.0 43310.0 61091.0 62204.0 True False 87203.7516976071 100244.93909306779 83726.87382099955 76697.82591605416 75414.13089150553 57196.51045877203 72037.07992689051 42173.158390738194 61984.34030218275 73481.09279340693 1.1867508822001547 1.3642276575133112 1.1394342495204688 1.043776337563339 1.026306605204326 0.7783840479833469 0.9803485112751891 0.5739321067163302 0.8435413511942799 1.0 16.165085461577178 -6.125731695351125 0.9436725339660632 0.8049923396504394 1.2868554500431546 0.6444610710634526 0.1257411098398147 0.3386669784196172 0.62771628375958 0.055556433968771426 0.1045127994547928 7.486318581589423e-07 6.125731695351125 0.48186311039271523 S(ph)PTVLCQK ddPTM_PC-9_Lapatinib_30min_R1 1 SPTVLCQK 8 0 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 S(0.998)PT(0.002)VLCQK 74.165 0.028172000000000003 9311100.0 24972.0 38545.0 37424.0 31972.0 43000.0 38819.0 40673.0 40035.0 36465.0 31156.0 True False 24615.894700696063 38455.751420697736 34347.14318081764 34323.32753546542 40470.82454125269 37158.80186150877 42778.84892548255 41895.17225495304 32357.927706526818 36541.27308723953 0.6736463352529473 1.0523922176681566 0.9399547492178619 0.939303002758581 1.1075373439954226 1.0168994871304822 1.1706994669657862 1.1465164925954132 0.8855172513906318 1.0 15.157239277462637 -4.397640607289921 2.103321980488234 1.037718346158852 8.334362088089273e-09 0.57032125728843 0.09074497962397493 2.5613499940023075 4.277880977085122 0.024747834156333595 7.5819692179382505 4.0027585393924946e-05 4.397640607289921 -1.0377183378244899 S(ph)PTVPSQNPSR ddPTM_PC-9_AZD4547_30min_R2 1 SPTVPSQNPSR 11 0 Q03164-2;Q03164;Q03164-3 Q03164-2 KMT2A Histone-lysine N-methyltransferase 2A;MLL cleavage product N320;MLL cleavage product C180 1 S(0.971)PT(0.018)VPS(0.011)QNPSR 76.52199999999999 0.02052 6713800.0 8869.9 18636.0 13765.0 16890.0 12463.0 11054.0 7951.7 12446.0 9030.2 14195.0 True False 11690.343694618789 24659.722553157273 13582.46710610878 12996.271447898727 10732.72757703938 10362.791632550769 8659.385895515958 10522.75668062785 9507.517936481325 13698.03737062174 0.8534320193702447 1.800237646164196 0.9915630056053998 0.9487688707706337 0.7835230176884992 0.7565165251173798 0.6321625252744449 0.7681944789547784 0.6940788435044098 1.0 13.74168158087352 -5.661220339084109 2.4335958044931862 0.7665559678223939 1.3329443717524672 0.41981059228811746 0.2401240676432718 0.22980132496543199 2.7491221920578695 0.06521270244036212 0.1315422954576916 2.1816227858080482e-06 5.661220339084109 0.5663884039300733 S(ph)PTVPSQNPSR ddPTM_PC-9_Lapatinib_30min_R1 1 SPTVPSQNPSR 11 0 Q03164-2;Q03164;Q03164-3 Q03164-2 KMT2A Histone-lysine N-methyltransferase 2A;MLL cleavage product N320;MLL cleavage product C180 1 S(0.997)PT(0.003)VPSQNPSR 84.365 0.012048 5714200.0 2764.6 11833.0 5794.1 8882.9 4936.9 2504.7 5548.0 4364.0 6249.5 6844.4 True False 2725.176297034453 11805.601415517358 5317.731463872797 9536.178098485734 4646.521248318849 2397.5798197408744 5835.248293427514 4566.767371565255 5545.615499847505 8027.445420410264 0.339482382540469 1.4706548344135613 0.6624438019039213 1.1879467998922082 0.5788293790830129 0.29867282730379996 0.7269122351914151 0.5688942287859067 0.6908319159352293 1.0 12.970725235585274 -6.291028273375991 24.011104283512655 0.6093449829383295 0.9367630479598344 0.13718629208778887 0.3243897663728003 684.3055541114239 555305.1576869949 0.09387824269674366 0.10646694899381554 5.116485251884068e-07 6.291028273375991 0.32741806502150494 S(ph)PVDSGTILR ddPTM_PC-9_AZD4547_30min_R2 1 SPVDSGTILR 10 0 P49454 P49454 CENPF Centromere protein F 1 S(1)PVDSGTILR 91.70100000000001 0.007903199999999999 4958700.0 12401.0 13760.0 13002.0 12858.0 12030.0 11231.0 8222.3 15880.0 11393.0 12833.0 True False 16344.260043176104 18207.65090853423 12829.58498464412 9893.786754119714 10359.84215291533 10528.723794570074 8954.068771294298 13426.110886097562 11995.210720729518 12383.720576061198 1.319818219636752 1.4702892233963347 1.0360040753378121 0.798934915670276 0.8365694372127388 0.8502068283842747 0.7230515834315001 1.084174243405604 0.9686273722872346 1.0 13.596157203812467 -5.406807637299809 3.862173836375937 0.8877484182435095 1.392569932728606 0.7772396441324746 0.10536019354985278 0.10178632949434152 2.634187034610982 0.029424982844261934 0.06583728463800417 3.919154303527637e-06 5.406807637299809 0.5048215144850966 S(ph)PVDSGTILREPTTK ddPTM_PC-9_AZD4547_30min_R2 1 SPVDSGTILREPTTK 15 1 P49454 P49454 CENPF Centromere protein F 1 S(0.996)PVDS(0.001)GT(0.003)ILREPTTK 76.76100000000001 0.0064244 9444200.0 30610.0 25357.0 26114.0 29057.0 23124.0 28844.0 25681.0 36346.0 30163.0 26146.0 True False 40343.343272447404 33553.15436683885 25767.711297415517 22358.357576174854 19913.6317492946 27040.380120254595 27966.55924931087 30729.56084799131 31757.354601015057 25230.636498223026 1.598982382996511 1.3298576264297561 1.0212866131708693 0.8861590779824178 0.7892639470548871 1.0717280208986812 1.108436533152088 1.2179463189585236 1.2586822612759572 1.0 14.622888981473931 -4.996622919161222 2.6015487174154934 1.0406838049527458 1.6095326187795618 0.6424307185879592 0.1326752876675729 0.23459700953427526 2.789042997947232 0.04065350836400656 0.2383080196835246 1.0078063277268263e-05 4.996622919161222 0.568848813826816 S(ph)PVEGLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPVEGLGR 8 0 Q9Y5U2-2;Q9Y5U2;A6NCC9;E9PME3;C9JHT9;C9JJV1 Q9Y5U2-2 TSSC4 Protein TSSC4 1 S(1)PVEGLGR 72.607 0.032219 10114000.0 23988.0 33590.0 32222.0 37291.0 37639.0 40361.0 34581.0 31864.0 26310.0 30495.0 True False 28048.69461540373 36924.59321142362 32990.294682615495 35201.7061690532 30263.908143822257 38244.39810852026 31305.237335240923 31027.603762698694 26694.733976370157 36023.50210171283 0.7786220933269583 1.025013978573392 0.915799207680224 0.9771872282062061 0.8401156572276541 1.061651307541857 0.8690225966051323 0.861315584339686 0.7410366127367968 1.0 15.136650822292049 -7.496825192908061 24.834281424586706 0.8537394277582514 0.9368316009753457 0.09236319418770411 0.09693437410204578 1288.6808118218212 1228375.9735836175 0.038128249081544094 0.02559527722567097 3.185479445327003e-08 7.496825192908061 0.08309217321709428 S(ph)PVEGLGR ddPTM_PC-9_Lapatinib_30min_R1 2 SPVEGLGR 8 0 Q9Y5U2-2;Q9Y5U2;A6NCC9;E9PME3;C9JHT9;C9JJV1 Q9Y5U2-2 TSSC4 Protein TSSC4 1 S(1)PVEGLGR;S(1)PVEGLGR 94.40899999999999 0.0067423000000000005 44448000.0 19174.5 44458.0 35950.4 33962.3 54497.0 33524.0 31184.0 32452.3 31730.0 34331.7 True False 18901.068113827358 44355.0602324914 32994.696884557125 36460.00083691159 51291.59360522437 32090.256668260903 32798.55493551613 33960.15233094574 28156.23326828729 40265.88860088529 0.4694064571919517 1.1015542379341954 0.8194205574748373 0.9054810933965076 1.2738224682839028 0.7969588598016277 0.8145493884566852 0.8433975633211057 0.6992577153175813 1.0 15.297270551164505 -10.39153437959254 11.560262665585865 0.9999999999530422 0.8743155644765895 0.036137239639359886 0.20502110792670628 0.0 0.0 0.19373630130368263 0.046987954928916005 4.059435267035864e-11 10.39153437959254 -0.1256844354764527 S(ph)PVGKS(ph)PPSTGSTYGSSQK ddPTM_PC-9_Lapatinib_30min_R1 2 SPVGKSPPSTGSTYGSSQK 19 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 2 S(0.998)PVGKS(0.871)PPS(0.083)T(0.012)GS(0.009)T(0.016)Y(0.005)GS(0.005)S(0.001)QK;S(1)PVGKS(1)PPSTGSTYGSSQK 87.51100000000001 0.0041147 4267000.0 28667.0 41218.0 33592.0 32036.0 41487.0 45910.0 44100.0 52551.0 34620.0 30699.0 True False 28258.203323116053 41122.56225342635 30830.19542886986 34392.03430896314 39046.81622658024 43946.53632143712 46383.28221704277 54992.71130685741 30720.731035238136 36005.28124615377 0.7848349560145349 1.142125844602845 0.8562687017522816 0.9551941581524804 1.0844746902442646 1.22055806260732 1.2882355202265674 1.5273512496929031 0.8532284701572731 1.0 15.13592091579371 -6.4973661732979435 2.59607492191087 1.2177460881565967 0.9433441219313222 0.25805352991295516 0.18811107803558005 0.35064929124915284 4.729719768577819 0.06349164047981683 0.06903981669255056 3.1815139124372144e-07 6.4973661732979435 -0.27440196622527446 S(ph)PVGLSSDGISSSSSSSR ddPTM_PC-9_AZD4547_30min_R2 4 SPVGLSSDGISSSSSSSR 18 0 O60583-2;O60583 O60583-2 CCNT2 Cyclin-T2 1 S(1)PVGLSSDGISSSSSSSR;S(1)PVGLSSDGISSSSSSSR;S(0.99)PVGLS(0.007)S(0.002)DGISSSSSSSR;S(1)PVGLSSDGISSSSSSSR 129.42 4.195e-05 27440200.0 7814.299999999999 15808.5 11531.7 10886.5 14274.300000000001 10874.600000000002 12972.400000000001 16133.400000000001 13366.3 12544.2 True False 10299.084852462785 20918.288472933396 11378.782123321078 8376.785619748343 12292.559837353225 10194.609542910854 14126.918469131286 13640.353738650274 14072.815330157731 12105.031376157323 0.8508102566961023 1.7280656136203913 0.940004347756859 0.6920085838230605 1.0154917782010269 0.8421795223918764 1.1670286536354109 1.126833406274105 1.1625591783162375 1.0 13.56331919834668 S(ph)PVGLSSDGISSSSSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPVGLSSDGISSSSSSSR 18 0 O60583-2;O60583 O60583-2 CCNT2 Cyclin-T2 1 S(1)PVGLSSDGISSSSSSSR;S(1)PVGLSSDGISSSSSSSR;S(1)PVGLSSDGISSSSSSSR;S(1)PVGLSSDGISSSSSSSR 208.07 2.4958e-20 28873900.0 4995.4 11183.4 8815.0 5519.299999999999 6264.58 6581.3 9045.1 3426.7 3530.6000000000004 5058.0 True False 5841.022556352667 12293.61404348422 9025.18303107366 5210.071514812029 5037.080519663812 6236.1650422835 8188.282647146923 3336.7527558887673 3582.22834576102 5974.975360894032 0.9775810281297426 2.057517111107339 1.510497112698257 0.8719820919951793 0.8430295047961699 1.0437139344705828 1.370429525239367 0.5584546469810866 0.5995385971307191 1.0 12.544717048502037 -5.737584828897688 6.269764750085186 0.902369399712684 1.5762288724205784 0.4280834373484894 0.3248886557683237 0.15052294608296035 19.477961594832866 0.08989643919800319 0.1516235144410551 1.8298486548319138e-06 5.737584828897688 0.6738594727078944 S(ph)PVGLSSDGISSSSSSSR ddPTM_PC-9_Lapatinib_30min_R1 3 SPVGLSSDGISSSSSSSR 18 0 O60583-2;O60583 O60583-2 CCNT2 Cyclin-T2 1 S(1)PVGLSSDGISSSSSSSR;S(0.999)PVGLS(0.001)SDGISSSSSSSR;S(0.997)PVGLS(0.003)SDGISSSSSSSR 163.91 1.6474e-07 25910600.0 6273.3 12805.9 9027.5 7280.1 11400.800000000001 7928.5 13585.3 9271.7 11422.6 11387.6 True False 6183.841591617675 12776.248725342159 8285.293797157734 7815.502839701673 10730.227358835207 7589.416537236205 14288.680360616587 9702.497030004948 10136.06650268951 13355.931486976795 0.46300339273583896 0.9565973543515196 0.620345634839219 0.5851709292850502 0.8034053910278082 0.568243146847268 1.0698378001226874 0.7264560348685327 0.7589187255544897 1.0 13.705192977370368 -7.242552085752612 24.986422433408222 0.8660078459544027 0.679809863646569 0.3129107121714043 0.1594601043634178 1160.265363257843 1534943.0459311337 0.058762049805507206 0.04544326743822787 5.720683413077012e-08 7.242552085752612 -0.1861979823078337 S(ph)PVGSGAPQAAAPAPAAHVAGNPGGDAAPAATGTAAAASLATAAGSEDAEK ddPTM_PC-9_Lapatinib_30min_R1 1 SPVGSGAPQAAAPAPAAHVAGNPGGDAAPAATGTAAAASLATAAGSEDAEK 51 0 P16989-2;P16989;P16989-3 P16989-2 YBX3 Y-box-binding protein 3 1 S(0.5)PVGS(0.5)GAPQAAAPAPAAHVAGNPGGDAAPAATGTAAAASLATAAGSEDAEK 66.278 6.807899999999999e-11 11098000.0 52147.0 87693.0 67976.0 67041.0 93194.0 84639.0 91173.0 93916.0 76031.0 74674.0 True False 51403.37421741141 87489.95224634165 62387.27567494819 71971.41878222012 87712.51214645362 81019.1872731457 95893.4918270848 98279.68021721438 67467.58813807592 87581.30140314944 0.586921790312229 0.998956978768935 0.7123355633615275 0.8217669483001313 1.0014981593239887 0.9250740280759545 1.0949082771181162 1.1221536862625363 0.7703423796766027 1.0 16.418335267041776 -6.208264493009615 4.20754686153311 0.9949525521333301 0.786543498851715 0.37106206116228846 0.13130208319934897 0.24669417911866856 9.241525334991078 0.038629577446363285 0.0496517518256957 6.190639393748319e-07 6.208264493009615 -0.20840905328161508 S(ph)PVIGSEVFLPNSNHVASGAGEAEER ddPTM_PC-9_AZD4547_30min_R2 4 SPVIGSEVFLPNSNHVASGAGEAEER 26 0 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-11;P29590-12;P29590-13;H3BVD2;P29590-2 P29590;P29590-2 PML Protein PML 1 S(1)PVIGSEVFLPNSNHVASGAGEAEER;S(0.996)PVIGS(0.004)EVFLPNSNHVASGAGEAEER;S(0.992)PVIGS(0.008)EVFLPNSNHVASGAGEAEER;S(1)PVIGSEVFLPNSNHVASGAGEAEER 159.96 5.8703e-11 55956000.0 16548.7 28051.6 54944.4 66099.0 57566.8 73712.0 42125.6 94081.0 56953.6 51778.5 True False 21810.84236565666 37118.73112106386 54215.80135596681 50860.89676936996 49574.64349529895 69102.77698738751 45874.69679189948 79542.94321630646 59964.05102292113 49965.750475148794 0.4365158565266543 0.7428834905527019 1.0850592824164993 1.0179151976245484 0.9921724986389554 1.3830028835803596 0.918122841259353 1.5919493344920002 1.2001030796634413 1.0 15.608651903424157 -4.759878785438367 0.7544924149943798 1.217559086785162 2.785828468035744e-17 0.6060602981324017 0.19053571729452495 1.907740680587623 0.8076140400285742 0.07514737359217821 1.9922839587944765 1.738285928546063e-05 4.759878785438367 -1.217559086785162 S(ph)PVIGSEVFLPNSNHVASGAGEAEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPVIGSEVFLPNSNHVASGAGEAEER 26 0 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-11;P29590-12;P29590-13;H3BVD2;P29590-2 P29590;P29590-2 PML Protein PML 1 S(0.998)PVIGS(0.002)EVFLPNSNHVASGAGEAEER;S(0.992)PVIGS(0.008)EVFLPNSNHVASGAGEAEER;S(1)PVIGSEVFLPNSNHVASGAGEAEER;S(0.999)PVIGS(0.001)EVFLPNSNHVASGAGEAEER 162.32 1.4166e-12 48004000.0 17229.199999999997 30770.199999999997 64174.0 52635.4 55299.5 54557.5 56880.0 38666.6 47680.1 33535.1 True False 20145.76326778863 33824.86210283259 65704.15154125038 49686.40918426919 44463.95994578228 51696.408657010295 51491.91462446151 37651.6427206492 48377.33126061297 39614.74816629444 0.5085420001465344 0.8538451881820094 1.6585780443545437 1.254240187914259 1.1224092542285478 1.3049788538349296 1.2998167856150242 0.9504450858199442 1.221194971568039 1.0 15.273750010492185 -5.01716627039745 6.487406609523107 1.2301030556770103 0.584115768368076 0.6061796062005089 0.1853863957219554 0.08687699109230143 16.918336500211826 0.047325729232321256 0.14803938956430335 9.612441939164364e-06 5.01716627039745 -0.6459872873089343 S(ph)PVIGSEVFLPNSNHVASGAGEAEER ddPTM_PC-9_Lapatinib_30min_R1 4 SPVIGSEVFLPNSNHVASGAGEAEER 26 0 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-11;P29590-12;P29590-13;H3BVD2;P29590-2 P29590;P29590-2 PML Protein PML 1 S(0.998)PVIGS(0.002)EVFLPNSNHVASGAGEAEER;S(0.999)PVIGS(0.001)EVFLPNSNHVASGAGEAEER;S(1)PVIGSEVFLPNSNHVASGAGEAEER;S(0.996)PVIGS(0.004)EVFLPNSNHVASGAGEAEER 166.91 2.1677e-13 40883200.0 23364.5 16651.8 43342.0 22819.3 36121.0 49515.0 30034.5 30737.499999999996 56426.0 26843.999999999996 True False 23031.317945475468 16613.243780183533 39778.58806495824 24497.507444953284 33996.43379661836 47397.358875102545 31589.539450062835 32165.676462760563 50070.70968787826 31483.949632618358 0.7315256889375246 0.527673432782134 1.2634560952208607 0.7780951161087203 1.0798020640141346 1.5054451372262836 1.0033537665596786 1.0216531546421963 1.5903566824412474 1.0 14.942328916518267 -5.277769444511487 0.7647954503239947 1.2083855925086846 0.4783433362008697 0.3743283677930249 0.2500754656047596 1.6237760683674802 1.151923715666737 0.10681639914384407 0.901741087686789 5.275098281606095e-06 5.277769444511487 -0.7300422563078148 S(ph)PVISRPK ddPTM_PC-9_Lapatinib_30min_R1 1 SPVISRPK 8 1 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2 A0A0U1RRM6 ENAH Protein enabled homolog 1 S(1)PVISRPK 61.65 0.030688999999999998 6115700.0 47249.0 59674.0 54487.0 44262.0 58249.0 42094.0 54205.0 55434.0 50809.0 44802.0 True False 46575.22059559462 59535.82851935963 50007.28918590239 47517.17513370354 54822.908341940216 40293.737745906634 57011.46967289802 58009.666011766356 45086.35537751049 52545.966005087466 0.8863710030772911 1.133023770342245 0.9516865515625065 0.9042972990372459 1.0433323908562704 0.7668283754076464 1.0849828066226475 1.1039794378535148 0.8580364736875378 1.0 15.68129239116134 S(ph)PVLEEAPFSR ddPTM_PC-9_AZD4547_30min_R2 2 SPVLEEAPFSR 11 0 Q9BZL4-3;K7EL81 Q9BZL4-3 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 S(1)PVLEEAPFSR;S(1)PVLEEAPFSR 136.38 8.0862e-05 29539000.0 8079.099999999999 10509.6 9760.9 21139.6 18185.1 9223.6 10755.599999999999 14935.1 14538.400000000001 11165.0 True False 10648.085744280615 13906.622673570604 9631.464088341241 16266.191823564239 15660.41276267501 8646.846833905847 11712.82756364192 12627.223469455645 15306.870143268141 10774.116748361515 0.9883024282152812 1.2907436403717705 0.8939446558165388 1.5097471285558453 1.4535217251155723 0.8025573729949441 1.087126475163095 1.1719961612051348 1.4207076552791158 1.0 13.395281982971602 -10.609433756317054 4.345226108151015 0.9999822208354525 1.178399379048227 0.05264725217310984 0.22880088903871534 163905482.63312766 2.125755610359009 31411.18073582812 0.055833766623949906 2.4579115120865253e-11 10.609433756317054 0.17841715821277448 S(ph)PVLEEAPFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPVLEEAPFSR 11 0 Q9BZL4-3;K7EL81 Q9BZL4-3 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 S(1)PVLEEAPFSR;S(1)PVLEEAPFSR;S(1)PVLEEAPFSR 120.57 0.00085304 22338800.0 20080.8 16949.0 23295.8 18639.2 34353.0 26659.699999999997 35259.2 18531.0 23270.1 21748.4 True False 23480.08282612137 18631.584707961258 23851.260221813467 17594.906053101742 27621.776255073906 25261.618400280404 31919.193321498133 18044.580885217474 23610.381189795924 25691.21275976033 0.913934388605344 0.7252123472015912 0.928382028705599 0.6848608595332766 1.0751448953915241 0.9832785488370253 1.2424167601574876 0.7023639192884022 0.9190060979439798 1.0 14.648987374155451 -6.269749798805765 24.969075466300712 0.984734492049087 0.8150545157557854 0.260019561588835 0.14370284986769857 910.873691017451 2736761.408753726 0.044756417938740384 0.051593470801156 5.373412746496112e-07 6.269749798805765 -0.16967997629330167 S(ph)PVLEEAPFSR ddPTM_PC-9_Lapatinib_30min_R1 2 SPVLEEAPFSR 11 0 Q9BZL4-3;K7EL81 Q9BZL4-3 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 S(1)PVLEEAPFSR;S(1)PVLEEAPFSR 156.36 0.0003137 24643000.0 5464.4 11898.0 2160.5 3201.8 11242.0 6064.5 13031.800000000001 11123.1 8054.9 8113.7 True False 5386.476653951767 11870.450912010947 1982.872029771175 3437.2710528916905 10580.767662622384 5805.135472039976 13706.522838912875 11639.91983287294 7147.672340142682 9516.142234174335 0.5660357444645869 1.2474015856322354 0.2083693140535765 0.36120425360476177 1.111875737273532 0.6100303388901224 1.4403444695992522 1.223176319398811 0.7511102886287248 1.0 13.216161120002733 -6.7818453049138645 1.7241544981296903 1.0943594154577407 0.6437038853104594 0.23253152142366984 0.3432682233573512 0.5362665824622219 3.2976459153867164 0.14926085398344588 0.13405751708328525 1.652550329518421e-07 6.7818453049138645 -0.4506555301472813 S(ph)PVPAQIAITVPK ddPTM_PC-9_AZD4547_30min_R2 2 SPVPAQIAITVPK 13 0 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 S(1)PVPAQIAITVPK;S(1)PVPAQIAITVPK 169.98 0.00024482 128474000.0 86593.0 82548.0 133393.0 134357.0 123366.0 130738.0 114752.0 140916.0 106783.0 121924.0 True False 114127.77275370929 109230.02668587817 131624.12166256213 103383.0694449573 106238.76035216566 122562.9321925475 124964.70569591991 119140.67012753943 112427.33137818471 117655.4778707772 0.9700166521703099 0.9283887895627534 1.118724976045118 0.8786932093251493 0.9029648451120083 1.0417103768611626 1.0621239908027957 1.0126232308400755 0.9555639347422935 1.0 16.844208966380478 -6.787902152398822 24.99411728233823 1.018175740539014 0.9623428581715339 0.14629123930184595 0.06554152387548695 465.6623709003233 439814.96357418684 0.02389738487237886 0.021081456778786183 1.6296631583471773e-07 6.787902152398822 -0.055832882367480074 S(ph)PVPAQIAITVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPVPAQIAITVPK 13 0 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 S(1)PVPAQIAITVPK;S(1)PVPAQIAITVPK 185.67 4.461e-05 75811000.0 193893.0 190568.0 224652.0 274780.0 291450.0 253679.0 257280.0 241046.0 241922.0 219063.0 True False 226715.25533868946 209486.33161996308 230008.55567745471 259384.9674487794 234342.4646913309 240375.6266636434 232908.57585410445 234718.79790934833 245459.65157854164 258777.387798246 0.8761014911992482 0.8095233258297191 0.8888278749331039 1.0023478853995045 0.9055755090705003 0.928889609362046 0.9000344961967466 0.9070297830363185 0.9485359353341667 1.0 17.981352033279656 -1.6335173718835696 0.3107797114958482 0.9487911103409375 6.360228787654852e-34 0.36822384312665024 0.043421668513394254 61.26818907827428 0.9332792380619789 0.04462175431321122 32.326120291200766 0.023253194706758365 1.6335173718835696 -0.9487911103409375 S(ph)PVPAQIAITVPK ddPTM_PC-9_Lapatinib_30min_R1 1 SPVPAQIAITVPK 13 0 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 S(1)PVPAQIAITVPK 181.51 8.193399999999999e-05 43805000.0 145220.0 122470.0 138350.0 107740.0 111660.0 115220.0 99239.0 96320.0 117170.0 71567.0 True False 143149.13616991337 122186.4282395341 126975.39704644421 115663.55901010423 105092.37833200645 110292.30919093855 104377.1098398437 100795.37883344771 103973.08074520077 83937.26059296688 1.7054301648475274 1.455687585898796 1.5127417329257409 1.3779763384343247 1.2520348840263698 1.3139850932921675 1.2435134182659933 1.2008418921631256 1.2386999529254674 1.0 16.357023759220347 -1.5228787452803376 0.1685710509964215 1.002275428315639 3.6278475648522828 0.9037760567525066 0.05721264609611061 17.02672269555634 0.18318214788577575 0.14802638243576527 11.246223167831994 0.029999999999999995 1.5228787452803376 2.625572136536644 S(ph)PVPSAFSDQSR ddPTM_PC-9_AZD4547_30min_R2 2 SPVPSAFSDQSR 12 0 Q9UQ35;Q9UQ35-2;I3L3Q8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.999)PVPS(0.001)AFSDQSR;S(0.999)PVPS(0.001)AFSDQSR 106.16 0.0017047999999999998 284330000.0 10364.6 8668.5 11501.099999999999 9639.3 4729.9 7517.6 12476.6 21110.2 11513.7 15408.1 True False 13660.327202927418 11470.423103243395 11348.587899314749 7417.1083107004315 4073.2350290169757 7047.52328359541 13586.993229623145 17848.103654137067 12122.290676315577 14868.667108860638 0.9187324662603322 0.7714493181710862 0.763255227669454 0.4988415072041244 0.2739475569124569 0.4739848724836675 0.913800351446855 1.2003835665606437 0.8152910134824108 1.0 13.859987703360412 -7.411239169954768 5.238173970367993 1.0148891782924887 0.6110529123264816 0.4718847791214613 0.19085851571319287 0.21807536350319576 8.62972253419143 0.09174209450391733 0.060536654643677947 3.8793666687220564e-08 7.411239169954768 -0.4038362659660071 S(ph)PVPSAFSDQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SPVPSAFSDQSR 12 0 Q9UQ35;Q9UQ35-2;I3L3Q8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.992)PVPS(0.008)AFSDQSR;S(1)PVPSAFSDQSR;S(0.999)PVPS(0.001)AFSDQSR;S(0.999)PVPS(0.001)AFSDQSR;S(1)PVPSAFSDQSR 129.76 0.00016585 294219000.0 29613.300000000003 50370.0 48683.9 45814.6 50008.8 43787.1 53223.6 23225.3 32936.6 33553.7 True False 34626.246800664325 55370.400716266995 49844.70881071893 43247.756494937275 40209.934631174576 41490.82739321589 48181.875302505076 22615.66048423947 33418.235465074635 39636.720199056945 0.8735901110578813 1.3969470843751697 1.257538680304453 1.0911033071794434 1.014461701907699 1.0467775129942023 1.2155868361593511 0.5705734574067395 0.8431130350151862 1.0 15.274549969008303 -7.748249202016201 24.999211323961717 0.7801323994019834 1.13441710747235 0.43830303158430006 0.1669939286451449 185.74671316987332 352045.3879183937 0.07845636978950259 0.04495278991496867 1.7854627665255495e-08 7.748249202016201 0.3542847080703665 S(ph)PVPSAFSDQSR ddPTM_PC-9_Lapatinib_30min_R1 4 SPVPSAFSDQSR 12 0 Q9UQ35;Q9UQ35-2;I3L3Q8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.993)PVPS(0.007)AFSDQSR;S(0.993)PVPS(0.007)AFSDQSR;S(0.999)PVPS(0.001)AFSDQSR;S(0.998)PVPS(0.002)AFSDQSR 109.95 0.0012506 258361600.0 34935.6 45003.0 34424.6 34344.2 39866.6 33587.2 46514.4 50882.9 31629.4 36305.7 True False 34437.411937595585 44898.79831847608 31594.342270798814 36869.98703689266 37521.72496875125 32150.753751587312 48922.68803529286 53247.105291159 28066.96389965225 42581.09187069561 0.8087489170585473 1.0544304137343063 0.7419805571623236 0.8658769753686532 0.8811827813784592 0.7550476593981735 1.1489298626689644 1.250487081281346 0.6591414796239171 1.0 15.377925323614937 -7.259297635189835 24.982582250217174 1.0355135272183567 0.8575123945438727 0.1883878967752085 0.16359263718062142 303.03262225239916 3534780.924229934 0.06319483856384575 0.04649697589536112 5.504303404948456e-08 7.259297635189835 -0.17800113267448392 S(ph)PVPVETLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPVPVETLK 9 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 S(1)PVPVETLK 86.189 0.011855 3094800.0 24541.0 29006.0 30332.0 22044.0 28615.0 17589.0 23655.0 18314.0 13385.0 17983.0 True False 28695.30659315586 31885.5239860242 31055.229914750573 20808.946147612274 23008.096164496244 16666.601876335135 21414.22715263074 17833.276905286973 13580.730303067829 21243.175546650324 1.3508011798961292 1.500977286376188 1.4618920719528412 0.9795591107325515 1.0830817696709294 0.7845626394102442 1.0080520732695912 0.8394826313102218 0.6392985019233282 1.0 14.374711823797218 -5.828955118148355 3.2819317913988395 0.8928475220778467 1.4517699365603873 0.7931168575533724 0.12498710151726791 0.10506019232664848 2.2741553406496404 0.0371993770286448 0.06089439121364171 1.4826713028307715e-06 5.828955118148355 0.5589224144825407 S(ph)PVPVETLK ddPTM_PC-9_Lapatinib_30min_R1 1 SPVPVETLK 9 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 S(1)PVPVETLK 69.65 0.039793 3166700.0 11683.0 26490.0 23726.0 22296.0 24018.0 27683.0 26844.0 23005.0 21695.0 26445.0 True False 11516.398277600192 26428.66403254076 21775.33986500851 23935.722217275652 22605.308461204826 26499.062622224865 28233.85097129922 24073.896283881484 19251.480641521975 31015.983014252444 0.37130528064540735 0.8520982236931287 0.702068345053011 0.7717221861475977 0.7288277289427599 0.8543679756997556 0.9103000526639836 0.7761771172243376 0.6206954857008901 1.0 14.920724229666693 -4.756586333556989 24.99935172913724 0.793507347634145 0.37130463728000906 0.6092059828794758 0.1032473306856084 101.82790292660194 524481.9420434905 0.025009460363778227 0.19983968679739125 1.7515142154546504e-05 4.756586333556989 -0.4222027103541359 S(ph)PVQLEEAPFSR ddPTM_PC-9_AZD4547_30min_R2 4 SPVQLEEAPFSR 12 0 Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 S(1)PVQLEEAPFSR;S(1)PVQLEEAPFSR;S(1)PVQLEEAPFSR;S(1)PVQLEEAPFSR 166.79 7.2923e-05 32858200.0 567.12 2459.5 12020.4 5192.3 5362.09 5705.4 5777.4 8768.599999999999 5007.87 5545.01 True False 747.4523631711982 3254.485276856102 11861.00164201016 3995.295455235322 4617.656359910705 5348.640436073383 6291.577407693186 7413.614352382559 5272.575784430765 5350.880887669688 0.1396877222390787 0.6082148612867802 2.2166446779523876 0.7466612580447994 0.8629712484446084 0.9995812929416038 1.1758021790750741 1.385494184605405 0.9853659416304025 1.0 12.385560699102975 -5.008398272615028 24.301937622511456 1.1704310717708228 0.25681867257001406 0.42272901726667667 0.3900206992131834 246.5276384977685 713397.0280580319 0.09691677902830172 0.31573406562544465 9.80848037298043e-06 5.008398272615028 -0.9136123992008087 S(ph)PVQLEEAPFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPVQLEEAPFSR 12 0 Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 S(1)PVQLEEAPFSR;S(1)PVQLEEAPFSR;S(1)PVQLEEAPFSR;S(1)PVQLEEAPFSR 158.89 6.453100000000001e-05 16915620.0 2450.48 2199.01 3726.0 3858.6800000000003 6350.300000000001 4505.5 6391.01 1651.72 4628.43 3535.53 True False 2865.2978648138474 2417.3131800492 3814.841970933691 3642.4906696093503 5106.004301009981 4269.223648520552 5785.60726589451 1608.364100142001 4696.112032620715 4176.49360175992 0.6860534548901136 0.578790107335631 0.9134078331464858 0.8721408475460017 1.222557673465219 1.022202846598773 1.385278613489682 0.3850991414099754 1.1244149950671143 1.0 12.028076512548942 -5.44461832006241 2.1786253669912417 1.0044991710742315 0.6247495050590216 0.25222530072862737 0.24856628568995656 0.46194564878995353 4.2162013424816 0.07097349113556846 0.19463288067310253 3.5923751203150955e-06 5.44461832006241 -0.3797496660152099 S(ph)PVQLEEAPFSR ddPTM_PC-9_Lapatinib_30min_R1 4 SPVQLEEAPFSR 12 0 Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 S(1)PVQLEEAPFSR;S(1)PVQLEEAPFSR;S(1)PVQLEEAPFSR;S(1)PVQLEEAPFSR 147.39 6.8656e-05 23010900.0 6064.509999999999 5432.6 4933.700000000001 2168.5 5983.63 9063.64 7869.0 7081.6 8963.900000000001 5210.32 True False 5978.028975305068 5420.021148477948 4528.0702306327485 2327.978723903939 5631.684647669204 8676.009245576788 8276.418316687295 7410.636988651816 7954.29118794833 6110.916869685002 0.9782540169971607 0.8869407429457199 0.740980498866802 0.38095408161295097 0.9215776892018986 1.4197557307016693 1.3543660457475537 1.2126882342999064 1.301652658279141 1.0 12.577173140010569 -6.595580729244395 5.382775005500632 1.2732989875863192 0.7441014314444083 0.6501641730691441 0.1778176692489467 0.12727927333440248 6.677353711421307 0.061790298022483835 0.061949114282439065 2.537577242151552e-07 6.595580729244395 -0.5291975561419109 S(ph)PVREPIDNLTPEER ddPTM_PC-9_AZD4547_30min_R2 4 SPVREPIDNLTPEER 15 1 G3XAC6;Q14498-2;Q14498;Q5QP23;Q5QP22;H0Y4X3;Q14498-3 G3XAC6 RBM39 RNA-binding protein 39 1 S(1)PVREPIDNLTPEER;S(1)PVREPIDNLTPEER;S(1)PVREPIDNLTPEER;S(1)PVREPIDNLTPEER 91.845 0.0017824000000000002 40925700.0 38921.2 35902.8 43951.9 45715.8 47312.4 42719.7 37781.8 45967.2 47618.7 32827.4 True False 51297.33198874812 47507.677982479894 43369.06908833871 35176.7286120692 40743.88993147061 40048.43040574262 41144.307006955074 38864.02546117277 50135.72726649719 31678.122717882903 1.6193299219650348 1.499699916108378 1.3690542673431858 1.110442336666979 1.2861838529487704 1.2642299154657457 1.2988240298636236 1.2268411801824761 1.582660933319594 1.0 14.95119922172679 -5.238944118853294 2.3919216711715148 1.2654558311762085 1.5976835132402234 0.4233098838546321 0.14260875196758335 0.3010815302407288 3.231598657843627 0.03745667964024719 0.13425357910333233 5.7684068133962595e-06 5.238944118853294 0.3322276820640149 S(ph)PVREPIDNLTPEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPVREPIDNLTPEER 15 1 G3XAC6;Q14498-2;Q14498;Q5QP23;Q5QP22;H0Y4X3;Q14498-3 G3XAC6 RBM39 RNA-binding protein 39 1 S(1)PVREPIDNLTPEER;S(1)PVREPIDNLTPEER;S(1)PVREPIDNLTPEER;S(1)PVREPIDNLTPEER 130.47 5.9026e-05 27227600.0 20715.0 20747.300000000003 23729.800000000003 25317.399999999998 31295.4 18825.2 24120.4 22892.1 22079.800000000003 17222.5 True False 24221.640360100402 22806.954829871072 24295.60842776765 23898.94815811824 25163.29102590864 17837.973372129425 21835.54109542653 22291.206631184894 22402.6753041223 20344.802916765024 1.1905566477687868 1.1210211729835498 1.1941923707575945 1.1746954864047585 1.2368412281434766 0.876782805176753 1.0732736603426654 1.0956708070549037 1.1011497823683265 1.0 14.31237268442001 -6.7286923766815905 24.999999727532952 1.03809816820438 1.1801016690251922 0.5778215260996903 0.06561145747938442 155.37139986713234 118614.55905219266 0.022078108815827835 0.022076575015814327 1.8677021697666024e-07 6.7286923766815905 0.14200350082081226 S(ph)PVREPIDNLTPEER ddPTM_PC-9_Lapatinib_30min_R1 4 SPVREPIDNLTPEER 15 1 G3XAC6;Q14498-2;Q14498;Q5QP23;Q5QP22;H0Y4X3;Q14498-3 G3XAC6 RBM39 RNA-binding protein 39 1 S(1)PVREPIDNLTPEER;S(1)PVREPIDNLTPEER;S(1)PVREPIDNLTPEER;S(0.994)PVREPIDNLT(0.006)PEER 110.26 0.0002572 29289700.0 42137.5 38445.3 35045.4 28282.2 36553.5 30259.9 30468.800000000003 31408.899999999998 33837.0 33103.4 True False 41536.6115229289 38356.2822699222 32164.10249115613 30362.167334653463 34403.49499694605 28965.754616272177 32046.32537901663 32868.27215782677 30025.920740593672 38825.27858249216 1.0698342172787239 0.9879203361909309 0.8284319820865416 0.7820205918199118 0.8861107055252383 0.7460540058902236 0.8253984658713454 0.846568868475508 0.7733600848941117 1.0 15.244708655949225 -5.126851700911799 2.8594626430284955 0.8259611020669478 1.0620276701683862 0.5737359703563905 0.06769237475164451 0.17456511144935538 2.6240762921005434 0.016588852423593203 0.06422719906452459 7.467036927393358e-06 5.126851700911799 0.23606656810143833 S(ph)PVSPLAAQGIPLPAQLTK ddPTM_PC-9_AZD4547_30min_R2 1 SPVSPLAAQGIPLPAQLTK 19 0 K7EIF1;K7EPF0;K7EQS3;K7EM48;K7EN63;Q96SI1-2;Q96SI1 K7EIF1 KCTD15 BTB/POZ domain-containing protein KCTD15 1 S(0.862)PVS(0.138)PLAAQGIPLPAQLTK 81.639 0.0021006999999999996 5940800.0 13705.0 10594.0 12723.0 16816.0 18186.0 18805.0 13454.0 16740.0 12823.0 11507.0 True False 18062.904918291144 14018.303323038645 12554.28470693948 12939.331004610123 15661.187813210163 17629.120377249612 14651.379936148467 14153.21764693156 13500.797601326654 11104.143432458211 1.6266815201154528 1.262438963284834 1.1305946094178143 1.1652705211630756 1.4103913470201928 1.5876164140422053 1.319451610587218 1.2745888715342675 1.2158342229138404 1.0 13.438810488021318 -8.596168111808582 1.4392424182931907 1.0025602103561815 1.3456834996511102 0.33947360154255546 0.15161113252737646 0.6621075879835925 2.9655207447537104 0.15620841107524183 0.04628318338318945 2.5341474930414105e-09 8.596168111808582 0.34312328929492875 S(ph)PVSPLAAQGIPLPAQLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPVSPLAAQGIPLPAQLTK 19 0 K7EIF1;K7EPF0;K7EQS3;K7EM48;K7EN63;Q96SI1-2;Q96SI1 K7EIF1 KCTD15 BTB/POZ domain-containing protein KCTD15 1 S(0.894)PVS(0.106)PLAAQGIPLPAQLTK;S(0.947)PVS(0.053)PLAAQGIPLPAQLTK 123.0 2.9124e-05 12523700.0 32999.0 31312.0 34966.0 41348.0 43055.0 33165.0 41658.0 39349.0 31579.0 33685.0 True False 38585.07894004119 34420.44842620113 35799.72204929344 39031.4056120247 34618.681822903556 31425.769016354243 37711.852662197896 38316.13044371176 32040.783133401495 39791.8238496867 0.9696735461484757 0.8650130880208986 0.8996753248739392 0.980890088362512 0.8699948500394291 0.7897544263129239 0.9477286792546661 0.9629146577560918 0.8052102174164045 1.0 15.28018440571344 -10.632965666666099 4.32770479702607 1.0000129540458433 0.8996628161466536 0.18332923586193117 0.0639471925396145 90500454.31940712 0.6408763094486245 12743.798395824322 0.015380200728348375 2.3282753131789755e-11 10.632965666666099 -0.10035013789918978 S(ph)PVSPLAAQGIPLPAQLTK ddPTM_PC-9_Lapatinib_30min_R1 2 SPVSPLAAQGIPLPAQLTK 19 0 K7EIF1;K7EPF0;K7EQS3;K7EM48;K7EN63;Q96SI1-2;Q96SI1 K7EIF1 KCTD15 BTB/POZ domain-containing protein KCTD15 1 S(0.794)PVS(0.206)PLAAQGIPLPAQLTK;S(0.862)PVS(0.138)PLAAQGIPLPAQLTK 101.23 0.00040594 9979400.0 46118.0 45918.0 56598.0 43449.0 48448.0 43296.0 41159.0 40520.0 44692.0 36380.0 True False 45460.348862994615 45811.679692193524 51944.73091459804 46644.38440161508 45598.38389243283 41444.33100790548 43290.01162746631 42402.7071255326 39658.31633237616 42668.234526697095 1.065437775133408 1.0736717888697647 1.2174098949910086 1.0931875883552236 1.0686728522573947 0.9713158153280087 1.0145723653126584 0.9937769302126068 0.9294576345211176 1.0 15.380874797276842 -6.567041179173632 2.4628093340935933 0.9825500862076142 1.117019838585574 0.6584531898001842 0.044565937193250846 0.18643260945968393 2.290504448416877 0.016626564787711465 0.01732838783742353 2.709934667629116e-07 6.567041179173632 0.13446975237795988 S(ph)PVSSLQIR ddPTM_PC-9_AZD4547_30min_R2 2 SPVSSLQIR 9 0 Q5JT35;P55197-1;P55197 Q5JT35 MLLT10 Protein AF-10 1 S(0.918)PVS(0.035)S(0.047)LQIR;S(0.999)PVS(0.001)SLQIR 79.07 0.020681 24879000.0 3755.3999999999996 4607.8 12321.1 5763.6 12167.7 5957.7 3981.6 7631.7 5344.200000000001 5768.7 True False 4949.539082827472 6097.181239559891 12157.714163536277 4434.891066732335 10478.42488479035 5585.164077189046 4335.954686618751 6452.396124019564 5626.6835015994675 5566.739568855624 0.889127113206226 1.0952876749744036 2.183991906421371 0.7966765845387002 1.882327124375326 1.003309748571049 0.7789038148788608 1.1590978963914433 1.0107682301286758 1.0 12.44261687522902 -6.9478876915180825 24.999996481575028 0.9848258604193344 1.375191761512071 0.1802056565305723 0.4042656050355632 172.53583600759526 82770.38286049261 0.13883914655159607 0.12244461469011456 1.1274889869464128e-07 6.9478876915180825 0.3903659010927366 S(ph)PVSSLQIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPVSSLQIR 9 0 Q5JT35;P55197-1;P55197 Q5JT35 MLLT10 Protein AF-10 1 S(1)PVSSLQIR;S(0.966)PVS(0.033)S(0.001)LQIR;S(0.988)PVS(0.01)S(0.002)LQIR;S(1)PVSSLQIR 124.67 0.0014513 27268700.0 11790.0 10199.2 14356.7 19920.100000000002 17633.4 12032.0 12210.8 13008.1 10681.1 13375.4 True False 13785.814136885534 11211.709171835419 14699.018176087948 18804.041378835565 14178.261852421047 11401.020738874548 11054.104625463688 12666.651158221219 10837.290880844068 15800.254140391859 0.8725058479688248 0.7095904326737215 0.9303026423170812 1.190110058468288 0.8973439114612504 0.7215719847017469 0.6996156218275573 0.8016738873737557 0.6858934536463914 1.0 13.947660143276785 -6.678867380037187 6.235032606890929 0.7646356172192383 0.9258733048837436 0.19801309108983078 0.13741590400622652 0.33422365256121667 20.07085729473157 0.04817487105043993 0.04791975730823048 2.094752030000662e-07 6.678867380037187 0.1612376876645053 S(ph)PVSSLQIR ddPTM_PC-9_Lapatinib_30min_R1 3 SPVSSLQIR 9 0 Q5JT35;P55197-1;P55197 Q5JT35 MLLT10 Protein AF-10 1 S(0.996)PVS(0.002)S(0.002)LQIR;S(0.999)PVS(0.001)SLQIR;S(1)PVSSLQIR 147.3 0.00038937 30210200.0 11305.4 11406.900000000001 17428.2 10320.9 13399.3 13221.599999999999 13355.0 16075.7 14058.2 5813.8 True False 11144.182922843556 11380.48802388785 15995.320670797502 11079.933415513107 12611.17951803738 12656.14298905496 14046.456553483138 16822.635709228147 12474.817476591124 6818.7075835984515 1.6343541332743898 1.6690095424039288 2.3457994751486697 1.6249315987921966 1.8494970437465297 1.8560911776738644 2.0599881108364486 2.467129658073752 1.8294988197760143 1.0 12.735282601708231 -5.040429936742307 24.873608782729622 1.9323751681301797 1.6430166930139734 0.0398412586931689 0.3821463988413909 1048.2958112763488 644940.6276936748 0.09231150057084067 0.24431104589320154 9.111084264464397e-06 5.040429936742307 -0.2893584751162064 S(ph)PVSTRPLPSASQK ddPTM_PC-9_AZD4547_30min_R2 3 SPVSTRPLPSASQK 14 1 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 1 S(1)PVSTRPLPSASQK;S(0.822)PVS(0.173)T(0.005)RPLPSASQK;S(1)PVSTRPLPSASQK 137.21 0.00028024 643450000.0 184094.0 179484.0 242507.0 303184.0 297271.0 272162.0 195912.0 274841.0 219464.0 220631.0 True False 242632.06260692366 237498.69299908107 239291.19872874097 233289.61294610618 256000.05292097235 255143.66711582022 213347.78846816736 232370.63866787992 231064.4189953642 212906.7758448496 1.1396164431315967 1.1155055636752127 1.1239247683836908 1.095735971860802 1.2024044415924362 1.1983820904871045 1.0020713883884989 1.0914196494958626 1.0852844775769208 1.0 17.699862339314883 -7.263077497073004 24.991964692006015 1.0523121837911131 1.1438308443653944 0.5773902334699259 0.04220595907235409 128.65660959900163 1962830.6656825575 0.01795983760718706 0.012854948965865245 5.456604827795803e-08 7.263077497073004 0.09151866057428126 S(ph)PVSTRPLPSASQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPVSTRPLPSASQK 14 1 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 1 S(0.999)PVS(0.001)TRPLPSASQK;S(1)PVSTRPLPSASQK;S(0.999)PVS(0.001)TRPLPSASQK;S(0.996)PVS(0.004)TRPLPSASQK 155.37 0.00040053 547511000.0 258245.0 258171.0 282057.0 305536.0 320165.0 294491.0 308606.0 284094.0 245056.0 199527.0 True False 301960.77792875323 283800.51068730076 288782.30858712975 288417.8084810771 257430.9665736835 279047.37353822327 279372.6055660434 276636.8335224745 248639.48039959584 235699.66564513708 1.28112518574115 1.2040768488597815 1.2252130600045588 1.2236665999998106 1.0921991164860814 1.1839107737995238 1.1852906316238017 1.1736836060640463 1.0548995889283126 1.0 17.846590186472305 -13.51320756835033 0.03464164885847862 7.520608075457651e-09 1.8575941977993642 0.7407792667601392 0.04183112685985144 493.26858780101753 1.5169716174084056 62.69007517642985 25.878459880907908 3.06755551886566e-14 13.51320756835033 1.857594190278756 S(ph)PVSTRPLPSASQK ddPTM_PC-9_Lapatinib_30min_R1 7 SPVSTRPLPSASQK 14 1 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 1 S(0.997)PVS(0.003)TRPLPSASQK;S(0.953)PVS(0.007)T(0.04)RPLPSASQK;S(0.995)PVS(0.002)T(0.002)RPLPSASQK;S(0.744)PVS(0.1)T(0.153)RPLPS(0.002)AS(0.001)QK;S(1)PVSTRPLPSASQK;S(0.896)PVS(0.052)T(0.052)RPLPSASQK;S(1)PVSTRPLPSASQK 136.39 0.00026437 1970849000.0 693233.0 552218.0 616942.0 525192.0 602668.0 575055.0 504957.0 540324.0 609671.0 458157.0 True False 683347.3702966373 550939.373149173 566219.4102249898 563816.371669152 567220.2531308761 550461.2381686782 531101.2026864236 565429.4255897403 541003.4318597537 537348.8269941715 1.2717016134922157 1.0252918504187019 1.0537278240511194 1.0492557968778586 1.0555903812125167 1.0244020467074528 0.9883732428659127 1.0522576717114027 1.0068011777117396 1.0 19.03549941105215 -4.760620925658146 24.991086097407067 1.0309595772996498 1.27170189472502 0.9087338652440001 0.0231176919119603 5.528767048631448 168715.89830417014 0.005814768539918069 0.03405028379529351 1.7353180108414847e-05 4.760620925658146 0.24074231742537022 S(ph)PVTTLLECMHK ddPTM_PC-9_AZD4547_30min_R2 3 SPVTTLLECMHK 12 0 P55265-5;P55265;P55265-4;A0A3B3ITG9;A0A3B3ISX1;A0A3B3IRQ9;P55265-3;P55265-2 P55265-5 ADAR Double-stranded RNA-specific adenosine deaminase 1 S(0.999)PVT(0.001)TLLECMHK;S(0.897)PVT(0.081)T(0.022)LLECMHK;S(0.954)PVT(0.023)T(0.023)LLECMHK 158.31 0.00026473 6923800.0 72099.0 72678.0 70198.0 78940.0 80476.0 87563.0 74521.0 102599.0 71986.0 72763.0 True False 95024.98224763747 96169.74220424787 69267.12865344161 60741.60261084227 69303.29651687563 82087.67176778041 81153.22463369388 86744.68204047396 75791.03299766831 70215.5895173336 1.3533316874620749 1.3696351887853502 0.986492161207906 0.8650728852151478 0.987007258548577 1.1690804325941895 1.1557721752611674 1.2354048814054313 1.079404638181644 1.0 16.09950375797679 -5.252644424793848 24.31459599151161 1.0659657470073893 1.3614835081431065 0.5806053998386482 0.10246018280592195 357.417483281845 988110.4648720232 0.030395164351967607 0.07770452793053242 5.589276250686587e-06 5.252644424793848 0.29551776113571715 S(ph)PVTTLLECMHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPVTTLLECMHK 12 0 P55265-5;P55265;P55265-4;A0A3B3ITG9;A0A3B3ISX1;A0A3B3IRQ9;P55265-3;P55265-2 P55265-5 ADAR Double-stranded RNA-specific adenosine deaminase 1 S(0.802)PVT(0.099)T(0.099)LLECMHK 81.703 0.008954700000000001 7788900.0 33960.0 42167.0 38172.0 34314.0 41181.0 33550.0 36667.0 32989.0 29896.0 27235.0 True False 39708.75725942598 46353.06108800536 39082.16524811616 32391.497827488976 33111.87867028202 31790.578938600484 33193.63631390877 32123.07370473472 30333.172442324678 32172.489907858624 1.2342456978975227 1.4407669788928246 1.21476967931443 1.0068073040121417 1.029198509817356 0.9881292691255191 1.0317397381730382 0.9984640230437424 0.9428294959202189 1.0 14.973539973566604 -5.632420148965795 3.2517721642141226 1.0003555094464316 1.3380802178761215 0.8748704033331147 0.05269636657751344 0.0692682362785739 1.4399835759300041 0.01386917704466347 0.026292773477855476 2.331201699486283e-06 5.632420148965795 0.33772470842968993 S(ph)PVTTLLECMHK ddPTM_PC-9_Lapatinib_30min_R1 2 SPVTTLLECMHK 12 0 P55265-5;P55265;P55265-4;A0A3B3ITG9;A0A3B3ISX1;A0A3B3IRQ9;P55265-3;P55265-2 P55265-5 ADAR Double-stranded RNA-specific adenosine deaminase 1 S(0.998)PVT(0.001)TLLECMHK;S(0.999)PVT(0.001)TLLECMHK 140.31 4.2536999999999996e-05 2464300.0 26288.1 32038.0 29245.3 25530.8 30107.8 32024.6 32123.0 29086.7 30494.4 27840.0 True False 25913.226873352894 31963.817979408854 26840.864324122653 27408.42020025211 28336.918398212278 30654.982510988775 33786.17176095387 30438.174268218863 27059.799551732092 32652.106905531797 0.7936157672252008 0.9789205355686761 0.8220254944582267 0.8394074011686112 0.8678434895547749 0.9388362778450698 1.0347317512680918 0.932196331351045 0.8287305817667687 1.0 14.994888465474084 -6.774348159162463 5.234823812853514 0.9489027345529218 0.8632119866782532 0.2932032408463118 0.06724466479644428 0.2512440011717656 19.581901526846387 0.023732123267545077 0.021908994190954705 1.6813256588789816e-07 6.774348159162463 -0.08569074787466868 S(ph)PVVELSK ddPTM_PC-9_AZD4547_30min_R2 2 SPVVELSK 8 0 P25098 P25098 ADRBK1 Beta-adrenergic receptor kinase 1 1 S(1)PVVELSK;S(1)PVVELSK 77.288 0.023754 29461000.0 69958.0 91185.0 74636.0 70874.0 71853.0 84054.0 86510.0 108652.0 98401.0 76238.0 True False 92203.18878320421 120658.76803013754 73646.277873704 54535.0942923846 61877.45122306116 78798.0900924936 94209.22240792376 91862.32997457637 103602.27597037688 73568.93082504108 1.2532897753058072 1.6400777702897948 1.0010513548014837 0.7412788752099436 0.841081289739222 1.0710783643150708 1.280557177485271 1.2486565856589649 1.4082340848035428 1.0 16.16680900441782 -5.273502475111322 24.722578335026295 1.0699451851557997 1.4466837803467023 0.33771097326324273 0.20870488534024362 703.0372842564389 1440833.0575235044 0.06110550036331116 0.12878179855044541 5.327181882710855e-06 5.273502475111322 0.3767385951909026 S(ph)PVVELSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPVVELSK 8 0 P25098 P25098 ADRBK1 Beta-adrenergic receptor kinase 1 1 S(1)PVVELSK;S(1)PVVELSK 99.788 0.0050921000000000004 16846100.0 81276.0 132832.0 102410.0 83391.0 114013.0 74252.0 87831.0 66506.0 68271.0 79870.0 True False 95034.42152582775 146018.68310389496 104851.84279208774 78718.87262726994 91672.97109916866 70358.09440682449 79511.01183862671 64760.28796893178 69269.33421895716 94349.79874942776 1.0072562187251528 1.5476311029733973 1.111309660241577 0.8343300533828365 0.9716286872283834 0.7457153628242499 0.8427258233988438 0.6863850143540932 0.7341757495733638 1.0 16.525731820072444 -5.640782774596082 3.4733554412986836 0.8188041809960586 1.2890343774720567 0.5864977218367704 0.15380480697910645 0.1425299706008389 3.321078661700281 0.04124793720381515 0.07664406041539293 2.2867423000853002e-06 5.640782774596082 0.4702301964759982 S(ph)PVVELSK ddPTM_PC-9_Lapatinib_30min_R1 1 SPVVELSK 8 0 P25098 P25098 ADRBK1 Beta-adrenergic receptor kinase 1 1 S(1)PVVELSK 87.789 0.011462 11019000.0 36589.0 63610.0 48781.0 51319.0 67223.0 64590.0 63321.0 57560.0 60820.0 57591.0 True False 36067.234150399185 63462.71495318676 44770.414480105435 55093.17045516543 63269.07530550298 61827.636266643975 66599.4515479676 60234.44773311094 53969.811137007004 67545.52761481627 0.5339692415473524 0.9395546558624567 0.6628183398819871 0.8156449790330843 0.9366878539508923 0.9153475951690092 0.9859935054139523 0.8917607110363052 0.7990138361902233 1.0 16.043572627242035 -6.054223134950856 3.8927735104248002 0.9180990348489818 0.7342480590846603 0.43157276760345487 0.106942421176409 0.23320078486793563 7.174411138249891 0.03060632105730378 0.04217508471444494 8.826263017954996e-07 6.054223134950856 -0.18385097576432152 S(ph)PY(ph)S(ph)PVLRR ddPTM_PC-9_Lapatinib_30min_R1 1 SPYSPVLRR 9 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5 Q14004 CDK13 Cyclin-dependent kinase 13 3 S(1)PY(1)S(1)PVLRR 49.813 0.041774 0.0 11209.0 7783.1 10961.0 8491.6 8836.9 11322.0 9855.3 11013.0 12823.0 8803.3 True False 11049.157604521144 7765.078710142242 10059.828890683568 9116.100591147193 8317.130916013855 10837.784452871081 10365.55921164675 11524.704184933127 11378.738707823755 10324.938675340083 1.0701426857779577 0.7520702015100807 0.9743233550345728 0.8829205555399511 0.8055380450712367 1.0496705882385404 1.0039342157453859 1.1162007395219251 1.1020635633411122 1.0 13.333845592376205 -6.825567903645765 9.350081849556872 1.059001133371308 0.8925751165037551 0.4438724007234911 0.08794108613130877 0.30052162101091323 41.05778780465506 0.029602609843724287 0.0261347374224622 1.4942803875006092e-07 6.825567903645765 -0.16642601686755298 S(ph)PYKFPSSPLR ddPTM_PC-9_Lapatinib_30min_R1 1 SPYKFPSSPLR 11 1 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 S(0.995)PY(0.001)KFPS(0.001)S(0.003)PLR 96.135 0.024428000000000002 0.0 10814.0 11817.0 10571.0 9472.6 8758.2 8019.6 10346.0 13573.0 8965.0 8699.8 True False 10659.790376955274 11789.63846253431 9701.89318524004 10169.246603667258 8243.059895283712 7676.620402600679 10881.665256633207 14203.6511306726 7955.267294364811 10203.548838245175 1.0447140054840531 1.1554448995573108 0.9508351789208067 0.9966382054791226 0.8078620513273662 0.7523480824462755 1.0664588790761016 1.3920304940800745 0.7796569037379129 1.0 13.31678339457699 -10.049946341507235 15.149903003045516 0.9999925627480825 0.9988112909231113 0.0 0.18258682449948987 0.0 0.0 0.1838165799078733 0.04458206909999711 8.913610618826871e-11 10.049946341507235 -0.0011812718249711862 S(ph)PYNGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPYNGVR 7 0 Q9UK58-6;Q9UK58 Q9UK58-6 CCNL1 Cyclin-L1 1 S(0.982)PY(0.018)NGVR 76.17 0.031649000000000004 15036000.0 14249.0 16347.0 16795.0 14081.0 22777.0 19299.0 15184.0 11591.0 12530.0 10107.0 True False 16661.07426942171 17969.822126440667 17195.456495392198 13292.087221217947 18314.010356062594 18286.926466052184 13745.661597359773 11286.748531679665 12713.227545568918 11939.319093032022 1.3954794356024358 1.5050960600364676 1.4402376183603085 1.1133036245739862 1.5339241889222095 1.531655727061079 1.1512935947395828 0.9453427321719537 1.0648201498348897 1.0 13.543432940681711 -7.459087046734639 4.32536031837954 1.0083624986676065 1.4145521036490127 0.7256157688846803 0.11679196475836726 0.12280655835640224 4.540782826313225 0.05519827031056529 0.03499374918609807 3.4746651087716255e-08 7.459087046734639 0.4061896049814062 S(ph)PYQEFTDHLVK ddPTM_PC-9_AZD4547_30min_R2 4 SPYQEFTDHLVK 12 0 H0YEN5;P15880;E9PQD7 H0YEN5 RPS2 40S ribosomal protein S2 1 S(0.996)PY(0.004)QEFTDHLVK;S(0.673)PY(0.325)QEFT(0.002)DHLVK;S(0.788)PY(0.212)QEFTDHLVK;S(0.999)PY(0.001)QEFTDHLVK 117.08 0.00036679 19486100.0 74825.9 88444.4 84688.0 83802.0 80511.0 100252.0 87321.0 112087.0 91968.3 82433.0 True False 98618.97972459406 117032.32267549181 83564.98178584373 64482.7436279934 69333.43737101965 93983.2265918652 95092.39983680841 94766.52965302367 96829.55658099441 79547.04576065241 1.239756659490873 1.4712340547206257 1.0505101853471819 0.810623990009815 0.8716029201088838 1.1814797858697297 1.195423399165949 1.191326827374141 1.2172615042467199 1.0 16.279520731908434 -5.27434295025178 24.57841828588609 1.064469369384279 1.3554953535038026 0.3997424114732613 0.14249759985844268 596.0997071639871 1135437.59221168 0.04212851444530155 0.08860011853635977 5.316882340633042e-06 5.27434295025178 0.2910259841195235 S(ph)PYQEFTDHLVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPYQEFTDHLVK 12 0 H0YEN5;P15880;E9PQD7 H0YEN5 RPS2 40S ribosomal protein S2 1 S(0.999)PY(0.001)QEFTDHLVK;S(0.798)PY(0.201)QEFT(0.001)DHLVK;S(1)PYQEFTDHLVK 135.61 3.4528e-05 12486500.0 45677.0 60929.0 56069.0 49028.0 55088.0 41566.0 57150.0 39848.0 41945.0 40217.0 True False 53409.21393812721 66977.62845426713 57405.89760286659 46281.12011092061 44293.90185251686 39386.205787238985 51736.338269830776 38802.03222244597 42558.36627285616 47508.023742403195 1.12421460062665 1.409817188301318 1.2083410986348622 0.9741748122772887 0.9323457042264299 0.8290432370076658 1.0890021136293575 0.8167469232742108 0.8958142839957953 1.0 15.535883573746428 -5.750810403400356 3.2974263286379775 0.9234926905125457 1.276501048559945 0.6863648575009182 0.0979336803350457 0.12147198010819552 2.742504070366916 0.026847335373481312 0.046632656042649656 1.7749641942307312e-06 5.750810403400356 0.3530083580473994 S(ph)PYQEFTDHLVK ddPTM_PC-9_Lapatinib_30min_R1 4 SPYQEFTDHLVK 12 0 H0YEN5;P15880;E9PQD7 H0YEN5 RPS2 40S ribosomal protein S2 1 S(0.993)PY(0.007)QEFTDHLVK;S(0.996)PY(0.004)QEFTDHLVK;S(0.999)PY(0.001)QEFTDHLVK;S(0.757)PY(0.243)QEFTDHLVK 129.29 0.00010179 20402600.0 76124.7 95843.0 86842.0 77288.8 95739.0 91277.0 93135.0 88608.4 91081.0 71634.7 True False 75039.14781843967 95621.08142207634 79702.18597981408 82972.87617987851 90107.82025011613 87373.29548707935 97957.07458694502 92725.4697448676 80822.49865455 84016.66244776224 0.8931460216608297 1.1381204470188184 0.9486473713398136 0.9875764373699955 1.0724994022006182 1.0399519921587472 1.1659243742019663 1.1036557159423002 0.9619817819447634 1.0 16.35838785561787 -6.264714318949299 24.436931805329795 1.0670785968954264 0.9992313304825814 0.1353950514800134 0.07788282455891635 411.4689059994681 3070300.4909246746 0.02337348043711488 0.027594662067114643 5.43607801797979e-07 6.264714318949299 -0.067847266412845 S(ph)PYSGPK ddPTM_PC-9_AZD4547_30min_R2 2 SPYSGPK 7 0 G3XAC6;Q14498-2;Q14498;Q5QP23;Q5QP22 G3XAC6 RBM39 RNA-binding protein 39 1 S(0.984)PY(0.012)S(0.004)GPK;S(0.998)PY(0.002)SGPK 82.305 0.022674 52718000.0 130831.0 148610.0 177237.0 177837.0 169819.0 185301.0 193471.0 232355.0 162250.0 167358.0 True False 172432.53654614743 196645.27627305753 174886.72157540146 136839.427204261 146242.5631393124 173714.09917706603 210689.5441970102 196449.87373672496 170826.20376005987 161498.84735981043 1.0677013450255615 1.2176265000513768 1.0828976456145447 0.8473090021465627 0.9055331696175647 1.075636773989109 1.3045885320011332 1.2164165685903974 1.0577549409963813 1.0 17.301164342673538 -7.010249141501784 24.51325538722374 1.1666372955252458 1.0246103006607046 0.1688933359316488 0.12217057524870918 642.326334731108 1536276.333234278 0.048715263405683475 0.04042021750372234 9.766767705320435e-08 7.010249141501784 -0.14202699486454118 S(ph)QAGHTLHHQESR ddPTM_PC-9_AZD4547_30min_R2 3 SQAGHTLHHQESR 13 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 S(0.65)QAGHT(0.35)LHHQESR;S(0.998)QAGHT(0.002)LHHQESR;S(1)QAGHTLHHQESR 124.04 0.00013682 10053400.0 2236.95 1540.4 5585.45 9836.3 2983.41 3565.1 5934.469999999999 6151.400000000001 2803.87 7145.87 True False 2948.2535685495345 2038.3041758362017 5511.383283531804 7568.693004320088 2569.2150189051627 3342.173733418378 6462.626333408278 5200.842475109603 2952.076843985944 6895.695266333552 0.42754986331017547 0.2955908138498658 0.7992498320567771 1.0975967922005303 0.37258244740725277 0.48467538142755184 0.9371972054740264 0.7542158222248263 0.42810430710282327 1.0 12.75148030510658 -14.522860890085447 0.050435953220265006 2.246788406280802 1.9771484548041045e-08 0.1702293665247726 0.252135905882896 1147.2794551557163 4.260937250549757 198.26680201009523 43.58511595854166 3.00012334185223e-15 14.522860890085447 -2.2467883865093174 S(ph)QAGHTLHHQESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SQAGHTLHHQESR 13 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 S(0.994)QAGHT(0.006)LHHQESR;S(0.998)QAGHT(0.002)LHHQESR;S(0.983)QAGHT(0.015)LHHQES(0.002)R 122.52 0.00015583 6367120.0 1728.03 2593.98 3565.94 5322.5 5142.71 2553.91 3644.6400000000003 6212.99 4157.96 3426.8 True False 2020.5513488517638 2851.493191383407 3650.9655335027583 5024.297580777822 4135.032892752631 2419.9784636983954 3299.393314291444 6049.905595707053 4218.762298912504 4048.0517134661277 0.49914168391926866 0.704411255888287 0.901906841100267 1.2411643764490814 1.021487170975893 0.5978131296218789 0.8150571059445166 1.4945228035456213 1.0421710485759101 1.0 11.98301200510058 -5.149278417115835 2.1849132561177274 1.0247698010349222 0.510012961077595 0.3734579689931766 0.2241913105617896 0.4301501346720469 3.6144791923902044 0.06732808968352352 0.31515010710201286 7.091230182669659e-06 5.149278417115835 -0.5147568399573272 S(ph)QAGHTLHHQESR ddPTM_PC-9_Lapatinib_30min_R1 2 SQAGHTLHHQESR 13 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 S(1)QAGHTLHHQESR;S(0.66)QAGHT(0.34)LHHQESR 109.15 0.0007069 4869400.0 2086.05 1352.43 4125.3 855.91 1786.12 2338.25 1215.1100000000001 1767.8400000000001 4293.9 1367.05 True False 2056.3025444652812 1349.2985314280518 3786.133758118507 918.8564766320595 1681.06393324703 2238.248498226972 1278.0224502211074 1849.980300217214 3810.27576522845 1603.342771020376 1.2825096302749033 0.8415533819816651 2.361400086463727 0.5730879842039606 1.0484744520207565 1.3959887671446192 0.7970987073511219 1.1538270753170745 2.376457382723951 1.0 10.646867170034515 S(ph)QAGVSSGAPPGR ddPTM_PC-9_Lapatinib_30min_R1 2 SQAGVSSGAPPGR 13 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 S(1)QAGVSSGAPPGR;S(1)QAGVSSGAPPGR 105.17 0.0025689 0.0 7441.7 8974.2 9747.6 8909.5 8927.7 8167.5 7218.0 6600.1 9141.5 6472.200000000001 True False 7335.5799933593535 8953.42079127321 8946.189954824125 9564.734351220724 8402.590238533528 7818.195064372413 7591.712722054753 6906.76474084965 8111.888005737411 7590.911146335598 0.9663635697936602 1.1794922399526893 1.178539674929902 1.2600245434091217 1.1069277556475887 1.0299415858854486 1.0001055967727328 0.9098729530227462 1.068631663493164 1.0 12.890057349144177 -6.770726909341761 2.808243383031587 0.9903855014976476 1.1534569314439533 0.4391412971391423 0.07819348444969607 0.23882372279104 3.8661616018522706 0.029546414491626132 0.027280197766317796 1.6954035596353408e-07 6.770726909341761 0.16307142994630575 S(ph)QCRNSPSNLSSSSDTGSVGGTYR ddPTM_PC-9_Lapatinib_30min_R1 2 SQCRNSPSNLSSSSDTGSVGGTYR 24 1 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 S(0.664)QCRNS(0.239)PS(0.087)NLS(0.005)S(0.002)S(0.002)SDTGSVGGTYR;S(0.841)QCRNS(0.151)PS(0.008)NLSSSSDTGSVGGTYR 72.513 0.0020402999999999997 3673000.0 18218.6 11139.7 14257.8 11712.4 11585.2 11140.0 10089.6 9233.7 12603.8 8947.3 True False 17958.79942311793 11113.906709071129 13085.578720699596 12573.768967421025 10903.781313379559 10663.568168608348 10611.990119208043 9662.731411279128 11184.227320102085 10493.82888347215 1.7113676640375906 1.0590897595610318 1.2469784733491767 1.1982060225152704 1.0390660486710515 1.016175152751303 1.0112600688507507 0.9208013127122736 1.0657908990413707 1.0 13.357253549678171 -1.8287277459639577 0.9291870041530429 1.0343924002265916 199.99999999652547 0.7888917839610441 0.09869050801611168 260.46312535201116 0.9596097205978511 0.03359487480700897 109417.97469279445 0.014834477494364657 1.8287277459639577 198.9656075962989 S(ph)QDKSLLDGEGPQAVGGQDVAFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQDKSLLDGEGPQAVGGQDVAFSR 24 1 A1X283 A1X283 SH3PXD2B SH3 and PX domain-containing protein 2B 1 S(0.867)QDKS(0.133)LLDGEGPQAVGGQDVAFSR 56.251999999999995 0.003397 5384600.0 11837.0 5961.3 8184.3 11853.0 10361.0 7111.2 6504.3 8054.4 6710.9 6338.6 True False 13840.770308593213 6553.098467140806 8379.44475113059 11188.914837944481 8330.836427060833 6738.276153447862 5888.165616945937 7842.980534342216 6809.034216724534 7487.738003670007 1.8484581460795448 0.8751773184276612 1.1190889354065976 1.4942983892412363 1.1125972119988163 0.8999081097849836 0.7863744182902683 1.0474432372631217 0.9093579681056128 1.0 12.870314240494366 -6.553979182842992 4.437293861918846 0.9258946373718517 1.2891388840230011 0.37361985135631826 0.24437156361618578 0.24321109874341026 11.192247872637582 0.08047989985524218 0.08280183537278167 2.792677700218483e-07 6.553979182842992 0.3632442466511494 S(ph)QDKSLLDGEGPQAVGGQDVAFSR ddPTM_PC-9_Lapatinib_30min_R1 1 SQDKSLLDGEGPQAVGGQDVAFSR 24 1 A1X283 A1X283 SH3PXD2B SH3 and PX domain-containing protein 2B 1 S(0.857)QDKS(0.143)LLDGEGPQAVGGQDVAFSR 44.178000000000004 0.027736 6460100.0 10747.0 9163.2 15506.0 13385.0 10298.0 10902.0 6027.9 10206.0 14674.0 11053.0 True False 10593.745809241575 9141.983173385333 14231.156534890928 14369.377551051068 9692.291886646986 10435.746873803258 6339.995167258779 10680.208018834794 13021.259595929634 12963.496322803268 0.8171981960304016 0.7052096861634656 1.0977869072140514 1.1084492326175002 0.7476603259876649 0.8050102081987245 0.4890652189337604 0.8238678634904932 1.0044558405917667 1.0 13.662167252655834 S(ph)QDLGVQFPGDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQDLGVQFPGDR 12 0 I3L2J0 I3L2J0 CIC 1 S(1)QDLGVQFPGDR 89.506 0.0074543000000000005 1925800.0 1616.0 1740.8 2801.6 2880.0 1568.5 1590.0 1117.4 4411.3 3242.5 1662.6 True False 1889.5568825451248 1913.6151194535944 2868.4007691271677 2718.642937085978 1261.1636845714606 1506.6176009649714 1011.5517827245652 4295.5080491587005 3289.9154282926715 1964.0162188656413 0.9620882273754735 0.9743377376785833 1.4604771292488983 1.3842263169579052 0.6421350661247961 0.7671105699092189 0.5150424792870641 2.187104163345281 1.6750958554674416 1.0 10.939591128154008 -7.76004456399524 24.99995996472631 1.6983249542953331 0.9747899987300674 0.3762915181644205 0.3867755677781109 37.16903506694489 666241.1994581899 0.2000689182312967 0.10741367780147318 1.737622517999645e-08 7.76004456399524 -0.7235349555652657 S(ph)QDVAVSPQQQQCSK ddPTM_PC-9_AZD4547_30min_R2 1 SQDVAVSPQQQQCSK 15 0 H3BQ37;H3BPW9;Q96F86;H3BTD6 H3BQ37 EDC3 Enhancer of mRNA-decapping protein 3 1 S(0.606)QDVAVS(0.394)PQQQQCSK 170.42 0.00015142 114070000.0 213930.0 169310.0 260520.0 345400.0 323190.0 281960.0 246080.0 293710.0 243390.0 293930.0 True False 281955.2899795708 224036.1464624953 257065.33457925616 265773.36637680396 278320.6471654783 264328.9966269237 267980.6432798737 248323.86828436484 256255.09850946712 283639.6001653292 0.994061794669092 0.7898620162061576 0.906309748107869 0.9370107919412125 0.9812474950720896 0.9319185208019274 0.9447927691467337 0.8754908275840915 0.9034531791756156 1.0 18.11369944204175 -5.526040564280883 15.340661369848693 0.9345600953613601 0.8809951439514078 0.09883197353640338 0.056679731601130136 1.4519480812319046 7031.238226089642 0.014823269736297317 0.026255750732462852 2.9782382409194406e-06 5.526040564280883 -0.05356495140995232 S(ph)QEADVQDWEFR ddPTM_PC-9_AZD4547_30min_R2 4 SQEADVQDWEFR 12 0 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 S(1)QEADVQDWEFR;S(1)QEADVQDWEFR;S(1)QEADVQDWEFR;S(1)QEADVQDWEFR 118.47 0.0016692999999999999 132971900.0 22191.1 24247.5 34450.7 39209.0 28224.1 30938.4 28377.7 40619.0 31767.7 28883.5 True False 29247.40819644584 32085.030189293873 33993.861208312504 30169.970823011347 24305.670898428703 29003.816957165604 30903.26032511075 34342.266881763026 33446.87576695507 27872.29745645318 1.0493361102413996 1.1511440791496481 1.2196289617468192 1.0824357364206514 0.8720368651491014 1.0405965637558323 1.108744636978457 1.2321290318969338 1.2000042629859071 1.0 14.766544305293037 -10.089880806152017 11.197864986412045 1.0000000693647804 1.1051436652962263 0.09006935946257433 0.10123978779462157 0.0 0.0 0.10924060836347635 0.026494739228785008 8.130536313483524e-11 10.089880806152017 0.10514359593144595 S(ph)QEADVQDWEFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SQEADVQDWEFR 12 0 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 S(1)QEADVQDWEFR;S(1)QEADVQDWEFR;S(1)QEADVQDWEFR;S(1)QEADVQDWEFR;S(1)QEADVQDWEFR;S(1)QEADVQDWEFR 156.11 0.00035378 165835500.0 62356.3 56913.8 56416.8 69305.6 70333.8 69765.9 76373.7 78513.2 69597.3 56292.1 True False 72911.9899969359 62563.825933799366 57761.99047390545 65422.6319237869 56552.396785407866 66107.25338815221 69139.03023829522 76452.31169161166 70615.02884734438 66497.41212198163 1.096463571592643 0.9408460259932137 0.8686351638458939 0.9838372627761337 0.8504450771959244 0.9941327230432108 1.0397251266179781 1.149703563672056 1.0619214582036587 1.0 16.02101057593123 -7.232930897704269 2.9544421888055337 1.0794400116095868 0.9444170862275193 0.3496613561038633 0.07236679595164801 0.2658984289572351 4.671574305301267 0.03164774840140301 0.02205854375265193 5.848831397878593e-08 7.232930897704269 -0.1350229253820675 S(ph)QEADVQDWEFR ddPTM_PC-9_Lapatinib_30min_R1 3 SQEADVQDWEFR 12 0 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 S(1)QEADVQDWEFR;S(1)QEADVQDWEFR;S(1)QEADVQDWEFR 169.15 0.00018763 127935500.0 30968.1 28692.0 31273.0 22638.0 27341.6 30288.5 32807.2 28411.3 32433.0 30416.0 True False 30526.489215145997 28625.565436831228 28701.854657271007 24302.874038154197 25733.42084365382 28993.131460942015 34505.79628913753 29731.39271854994 28780.054005369082 35673.36507322756 0.855722165612455 0.8024352448408176 0.8045737933148173 0.681261046953858 0.721362304644662 0.8127388992159033 0.9672705733901656 0.8334339263346648 0.8067658867138434 1.0 15.122559691386545 -7.0113378182804755 22.64655792216704 0.8882753605032085 0.7709217253842888 0.4301933407654278 0.0694160411166025 172.061742008062 343682.5320491155 0.02646297897935944 0.021773932272157803 9.742315317110253e-08 7.0113378182804755 -0.11735363511891972 S(ph)QEALHEQSSYILSSAETPARPR ddPTM_PC-9_AZD4547_30min_R2 1 SQEALHEQSSYILSSAETPARPR 23 1 Q9NVE5;Q9NVE5-3 Q9NVE5 USP40 Ubiquitin carboxyl-terminal hydrolase 40 1 S(0.905)QEALHEQS(0.03)S(0.03)Y(0.027)ILS(0.003)S(0.003)AET(0.001)PARPR 46.958 0.02336 5735100.0 1435.0 1261.6 0.0 1930.3 1977.8 1321.1 829.13 2312.3 0.0 0.0 True False 1891.300150145769 1669.3875280673533 0.0 1485.299157837711 1703.2166093130454 1238.491408156579 902.920963762358 1954.98716636797 0.0 0.0 0.0 S(ph)QEALHEQSSYILSSAETPARPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQEALHEQSSYILSSAETPARPR 23 1 Q9NVE5;Q9NVE5-3 Q9NVE5 USP40 Ubiquitin carboxyl-terminal hydrolase 40 1 S(0.776)QEALHEQS(0.069)S(0.047)Y(0.098)ILS(0.004)S(0.004)AET(0.001)PARPR 44.711999999999996 0.029089 3628400.0 1031.4 1140.8 1264.4 2924.9 2507.1 3287.5 2401.4 3553.5 2328.0 2208.1 True False 1205.9956489214355 1254.0510847154524 1294.5480912637026 2761.0273356537436 2015.8517523679373 3115.0977126870075 2173.922007369582 3460.2243902444707 2362.0425958566966 2608.411050690019 0.46234877305952454 0.4807720333740001 0.49629757967834404 1.0585092924381503 0.772827485083178 1.1942510793545948 0.8334276941490879 1.3265640740668985 0.9055484545780663 1.0 11.34895552158672 -5.757625561380852 24.79895584296948 1.0166856367961046 0.47990253614640327 0.7170534379607653 0.15348003493486817 43.377541540454374 282052.05582318257 0.03998505210177742 0.06600325568494354 1.747328009311388e-06 5.757625561380852 -0.5367831006497013 S(ph)QEDLNEPIK ddPTM_PC-9_AZD4547_30min_R2 2 SQEDLNEPIK 10 0 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 S(1)QEDLNEPIK;S(1)QEDLNEPIK 118.52 0.0015063 0.0 11716.7 16405.300000000003 19938.5 16477.5 19071.5 20070.5 22258.7 22075.0 22678.9 16519.800000000003 True False 15442.366877500308 21707.992401873307 19674.10246241552 12678.86694983727 16423.75142305276 18815.48846219559 24239.68117918446 18663.81598303549 23877.660354108015 15941.446830235778 0.9686929324514713 1.361732886170674 1.2341478582169907 0.7953397884682306 1.0302547565445694 1.1802873768338695 1.520544617895636 1.1707730284327929 1.497835209588367 1.0 13.960494952421188 -7.0077187272890535 22.50355175943615 1.317075989992327 1.088613268740112 0.20931654295777524 0.19889336277691816 150.9330647666416 440040.21978731867 0.07227995335235853 0.06090804161460504 9.82383982291721e-08 7.0077187272890535 -0.228462721252215 S(ph)QEDLNEPIK ddPTM_PC-9_Lapatinib_30min_R1 2 SQEDLNEPIK 10 0 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 S(1)QEDLNEPIK;S(1)QEDLNEPIK 143.98 0.00012377 3445900.0 13161.2 23777.0 22798.0 18958.1 24145.0 24899.0 24625.0 26151.0 24200.0 23590.0 True False 12973.518874531514 23721.945817354517 20923.63644282494 20352.341916367663 22724.83857089643 23834.127812403905 25899.96200894961 27366.070928919118 21474.341162702567 27667.50006830082 0.46890824405908366 0.85739390110396 0.7562532354268446 0.7356046576714652 0.8213549657467142 0.8614485498713749 0.9361150065966274 0.9891052990462607 0.7761576257229734 1.0 14.755904672864817 -3.727279748254046 0.335233013643065 0.9430881992095861 1.2986078519336634e-17 0.5911454558669813 0.09353228342948744 10.665023915674553 0.5551401288463301 0.08785474472214108 4.6756338009948895 0.00018737871302102892 3.727279748254046 -0.9430881992095861 S(ph)QEDLNEPIKR ddPTM_PC-9_AZD4547_30min_R2 1 SQEDLNEPIKR 11 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 S(1)QEDLNEPIKR 62.357 0.025405 67279000.0 27295.0 38689.0 51707.0 50834.0 52654.0 59199.0 64452.0 61424.0 64746.0 48019.0 True False 35974.24222873085 51194.462645369254 51021.33139524638 39115.006677470934 45343.90097419816 55497.277171645845 70188.10313993173 51932.332183101775 68168.34137842122 46337.869425846075 0.7763464888324223 1.1048082978285207 1.10107201792899 0.8441261361847074 0.9785495435167006 1.1976657075366286 1.5147028555607827 1.1207319807011942 1.471115142389319 1.0 15.499904091438209 -6.84820391044806 4.040313642076984 1.2943672825403472 0.9693925893498755 0.44175609229498647 0.16930657511826608 0.20020292885325217 6.166802614306983 0.058599395459282035 0.052058200080251874 1.4183914005494497e-07 6.84820391044806 -0.3249746931904717 S(ph)QEDLNEPIKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQEDLNEPIKR 11 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 S(1)QEDLNEPIKR;S(1)QEDLNEPIKR 94.781 0.0029756 25379000.0 52705.0 67825.0 65975.0 82860.0 98032.0 77069.0 92620.0 87665.0 72874.0 76265.0 True False 61626.91552879996 74558.21776019085 67548.09421158089 78217.62283574455 78823.33332860019 73027.36596777943 83846.36308926893 85363.88663874523 73939.64438593689 90091.24078659237 0.6840500251825974 0.8275856466091297 0.7497742690833666 0.8682045241337725 0.874927824729559 0.8105934087506492 0.9306827429304001 0.9475270391819192 0.8207195698534634 1.0 16.459099224899674 -1.6881151991239052 0.1586726187029126 0.996160099031782 1.298914882744885e-11 0.637472311215703 0.05383736581245549 39.50020692542575 0.4260238408054445 0.16146255905565254 9.080786365015921 0.020506181683449302 1.6881151991239052 -0.9961600990187929 S(ph)QEDLNEPIKR ddPTM_PC-9_Lapatinib_30min_R1 2 SQEDLNEPIKR 11 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 S(1)QEDLNEPIKR;S(1)QEDLNEPIKR 91.09299999999999 0.010172 85252000.0 70026.0 81310.0 87356.0 96693.0 76284.0 71637.3 69131.0 73070.6 74914.0 66574.8 True False 69027.41639880434 81121.73169067154 80173.9268839114 103804.12577839232 71797.12510011443 68573.53967370259 72710.26491941916 76465.72683334016 66476.39644060735 78082.16547465522 0.8840356306615245 1.0389277909691546 1.0267892340913 1.3294217078557615 0.9195073505411314 0.8782228215220408 0.9312019521669166 0.9792982349876075 0.8513646622951946 1.0 16.25270544367239 S(ph)QEDMNEPLK ddPTM_PC-9_Lapatinib_30min_R1 1 SQEDMNEPLK 10 0 E3W994;J3KR49;O75122;A0A0U1RQI6;E7ERI8;E7EW49;O75122-3 E3W994;E7ERI8 CLASP2 CLIP-associating protein 2 1 S(1)QEDMNEPLK 66.056 0.03781 0.0 5737.0 3526.8 6969.5 4246.6 6835.2 5021.8 5472.9 5033.6 4381.4 6172.7 True False 5655.189327963052 3518.633911285947 6396.494613048 4558.90913024232 6433.16697452024 4807.029320387563 5756.259982894633 5267.479432060236 3887.9205938126024 7239.6429703942595 0.7811420191699149 0.48602312650983226 0.8835373013843053 0.6297146349461553 0.8886027944786757 0.663987069534422 0.7951027428333467 0.7275882876546573 0.5370320898021954 1.0 12.821702835901178 -11.829487754086417 2.4034727923235004 2.5644977372670117 0.7133160642510896 0.3159489409121051 0.12781021106824064 21218163.32088969 2312291.430480074 181320368.49028945 0.030463466831190035 1.4808540107015118e-12 11.829487754086417 -1.851181673015922 S(ph)QEDMNEPLKR ddPTM_PC-9_Lapatinib_30min_R1 2 SQEDMNEPLKR 11 1 E3W994;J3KR49;O75122;A0A0U1RQI6;E7ERI8;E7EW49;O75122-3 E3W994;E7ERI8 CLASP2 CLIP-associating protein 2 1 S(1)QEDMNEPLKR;S(1)QEDMNEPLKR 69.92 0.015364 12450600.0 53616.0 54429.0 41942.0 51109.0 49322.0 46848.0 44507.0 52017.0 52133.0 38770.0 True False 52851.426008029775 54302.97299460778 38493.690660801956 54867.72635462596 46420.97693078289 44844.420248021925 46811.35468557647 54433.89971739459 46261.232555172435 45471.342842222264 1.1623018522108557 1.1942240892913534 0.8465483589162616 1.2066440734993802 1.0208842323363023 0.9862127978851284 1.029469370368142 1.197103413160039 1.0173711543046122 1.0 15.472669989376536 S(ph)QEDQLSR ddPTM_PC-9_AZD4547_30min_R2 1 SQEDQLSR 8 0 F5H875;F8VVT7;Q9HD42-2;Q9HD42 F5H875 CHMP1A Charged multivesicular body protein 1a 1 S(1)QEDQLSR 81.525 0.041267 0.0 13489.0 12041.0 15481.0 23029.0 24687.0 15485.0 11171.0 23785.0 15737.0 17123.0 True False 17778.22141137024 15933.017775411385 15275.711824894299 17720.019844503255 21259.63617863847 14516.720502085098 12165.197358905494 20109.574774926346 16568.825692277747 16523.52898183558 1.0759336840764433 0.9642624038077248 0.9244824057673747 1.0724113392473837 1.2866280684961016 0.8785484334516809 0.7362348183780094 1.2170266289382206 1.0027413460219037 1.0 14.012234220113003 S(ph)QEEPKDTFEHDPSESIDEFNK ddPTM_PC-9_AZD4547_30min_R2 5 SQEEPKDTFEHDPSESIDEFNK 22 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 S(0.787)QEEPKDT(0.213)FEHDPSESIDEFNK;S(0.938)QEEPKDT(0.062)FEHDPSESIDEFNK;S(0.954)QEEPKDT(0.046)FEHDPSESIDEFNK;S(0.853)QEEPKDT(0.122)FEHDPS(0.016)ES(0.008)IDEFNK;S(0.795)QEEPKDT(0.205)FEHDPSESIDEFNK 79.408 0.00024339 58330300.0 178415.7 173813.7 189850.2 160087.1 196055.3 227234.6 218690.9 228558.0 214067.2 211734.8 True False 235148.1813229004 229995.5794128412 187332.6623020828 123181.49241603956 168836.4057558155 213025.58454007746 238153.96643959038 193239.612840345 225382.35516514964 204322.02909905772 1.1508704291934073 1.1256523852420075 0.9168500485635924 0.602879155807129 0.8263250247674548 1.0425972445526182 1.1655814475302149 0.9457600518770307 1.1030741822551187 1.0 17.640485231903185 -6.875860219408874 8.307101065731228 1.0566811356176253 0.9176508240439826 0.1457674338019086 0.15317994847767727 0.5425908090064057 37.33515871924833 0.06103546827152447 0.053849996278106965 1.330882702573207e-07 6.875860219408874 -0.13903031157364276 S(ph)QEEPKDTFEHDPSESIDEFNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SQEEPKDTFEHDPSESIDEFNK 22 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 S(0.804)QEEPKDT(0.195)FEHDPSESIDEFNK;S(0.813)QEEPKDT(0.187)FEHDPSESIDEFNK;S(0.794)QEEPKDT(0.204)FEHDPS(0.002)ESIDEFNK 70.987 0.00070937 35111800.0 182587.0 243707.0 198993.0 219964.0 234665.0 188015.0 233656.0 181217.0 176385.0 180214.0 True False 213495.37284236765 267900.6203565467 203737.74780515477 207640.13021291 188684.07780679784 178155.1624185088 211522.4121570527 176460.24576528274 178964.29693736424 212885.37162676116 1.0028653975186044 1.2584266279518745 0.9570302846470617 0.9753611938022341 0.8863177228429111 0.8368595787354393 0.993597683770879 0.8288979389089244 0.8406603777883402 1.0 17.69971729314858 -5.44086519177702 5.341713820670051 0.9054020604456379 1.1303390753647513 0.5222735378123411 0.08347293380318381 0.15458701327315394 7.421972349353049 0.021318499850959963 0.04506115240440517 3.623554587790505e-06 5.44086519177702 0.22493701491911344 S(ph)QEEPKDTFEHDPSESIDEFNK ddPTM_PC-9_Lapatinib_30min_R1 5 SQEEPKDTFEHDPSESIDEFNK 22 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 S(0.851)QEEPKDT(0.149)FEHDPSESIDEFNK;S(0.5)QEEPKDT(0.5)FEHDPSESIDEFNK;S(0.565)QEEPKDT(0.434)FEHDPS(0.001)ESIDEFNK;S(0.997)QEEPKDT(0.003)FEHDPSESIDEFNK;S(0.994)QEEPKDT(0.006)FEHDPSESIDEFNK 126.86 3.8067e-07 67495100.0 222474.0 237032.0 202267.0 227544.0 266234.0 259416.0 214112.0 247862.0 236026.0 213248.0 True False 219301.47996326507 236483.1669672023 185637.3880331986 244278.34482453266 250574.63955618328 248321.38240823208 225197.6717019377 259378.57338471778 209442.26641603446 250107.63266490056 0.8768284183357562 0.9455255901128271 0.7422299993615926 0.976692883066955 1.0018672236680934 0.9928580737915275 0.9004030356948852 1.0370678040531398 0.837408535614943 1.0 17.932189560103538 -5.869848235239524 19.310982309052704 0.9654822450313898 0.8630585896022657 0.32712485904123556 0.0712391840231839 2.406579351034139 415.7261817790535 0.019103201523148317 0.028334862716525973 1.3494343617657578e-06 5.869848235239524 -0.10242365542912413 S(ph)QEGLRPR ddPTM_PC-9_Lapatinib_30min_R1 2 SQEGLRPR 8 1 Q27J81-2 Q27J81-2 INF2 Inverted formin-2 1 S(1)QEGLRPR;S(1)QEGLRPR 76.843 0.015159 16704000.0 25074.8 22929.3 21616.6 18915.6 21155.3 15537.5 22237.0 22164.8 21815.3 25930.4 True False 24717.22875384485 22876.208614621988 19839.366590489044 20306.716324591827 19910.986846920074 14872.997344681533 23388.323053523363 23194.657524580565 19358.231188706817 30412.43508991385 0.8127342871680212 0.7521991759945845 0.6523439024804917 0.667710963116086 0.6546988686717646 0.48904329103242694 0.7690381577264754 0.7626701859290764 0.6365235513524167 1.0 14.892373715533234 -10.676951112183938 8.043291742993754 1.0000000492349888 0.6864291678619462 0.5315978625826285 0.08768486670898488 8.11240671767029e-08 8.479937170232185e-09 0.08887897558031008 0.02155631436162192 2.1040152719775245e-11 10.676951112183938 -0.31357088137304256 S(ph)QEIEELER ddPTM_PC-9_AZD4547_30min_R2 2 SQEIEELER 9 0 K7EQS5;K7EQS9;K7EPK6;K7EK08;O43310;O43310-2 K7EQS5 CTIF CBP80/20-dependent translation initiation factor 1 S(1)QEIEELER;S(1)QEIEELER 84.821 0.012912 7976900.0 41962.0 44709.0 46927.0 54342.0 48073.0 43818.0 41506.0 43824.0 46770.0 48413.0 True False 55305.043136178945 59160.309917853 46304.717318442905 41814.29147553066 41398.89375038224 41078.053533120095 45199.95359222373 37052.00777533622 49242.16671715259 46718.075605770355 1.1838039649336065 1.2663259166982008 0.9911520694727333 0.8950345435539728 0.886142958877974 0.8792753768317967 0.9675046115692505 0.7930979025762731 1.054028148177201 1.0 15.511693228014137 -5.381534697098478 3.7927657945185045 0.9159803165900995 1.2251145151128728 0.7306570773709649 0.07142966800261087 0.10138595526627293 2.5486370281660538 0.0178271349388209 0.04066915312125185 4.153988624457602e-06 5.381534697098478 0.30913419852277335 S(ph)QEIEELER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQEIEELER 9 0 K7EQS5;K7EQS9;K7EPK6;K7EK08;O43310;O43310-2 K7EQS5 CTIF CBP80/20-dependent translation initiation factor 1 S(1)QEIEELER 69.86399999999999 0.039218 3463200.0 24735.0 30973.0 24141.0 26756.0 32605.0 29229.0 36889.0 31006.0 29284.0 21437.0 True False 28922.146961481212 34047.79474657408 24716.612995252322 25256.948064122374 26216.284306950907 27696.17978528626 33394.60686676792 30192.125353572555 29712.22310011491 25323.35840480136 1.1421133997770814 1.3445212993596674 0.976040089159975 0.9973775065843401 1.035260958987977 1.0937008963248336 1.318727410991278 1.1922638723877976 1.173312900491169 1.0 14.628181128417356 S(ph)QEIEELER ddPTM_PC-9_Lapatinib_30min_R1 2 SQEIEELER 9 0 K7EQS5;K7EQS9;K7EPK6;K7EK08;O43310;O43310-2 K7EQS5 CTIF CBP80/20-dependent translation initiation factor 1 S(1)QEIEELER;S(1)QEIEELER 91.09299999999999 0.0080671 8226000.0 36660.0 34847.0 24189.1 31013.0 25386.8 31017.0 26864.0 25163.0 29895.0 24386.6 True False 36137.22167737937 34766.313912493315 22200.365570626225 33293.79947633518 23893.598336369156 29690.475214158458 28254.88647343848 26332.16484204778 26527.910291693934 28601.791316898063 1.2634600846146773 1.215529248755592 0.7761879430785915 1.1640459545855457 0.8353881780213085 1.0380634864857992 0.9878712196863477 0.9206474010769605 0.9274912189161079 1.0 14.803817884702635 -5.1258427197797465 7.066902784469844 0.9609038325473093 1.2510141583589725 0.55752125055367 0.10120049591525371 0.15790964024687465 8.231389650582228 0.02362156105628867 0.06384016993663351 7.4844049998011685e-06 5.1258427197797465 0.2901103258116632 S(ph)QEMVHLVNK ddPTM_PC-9_AZD4547_30min_R2 5 SQEMVHLVNK 10 0 P16070;P16070-5;P16070-7;P16070-3;P16070-4;P16070-8;P16070-17;H0Y2P0;H0YD13;H0YE40;P16070-10;P16070-16;P16070-11;P16070-13;P16070-14;P16070-12;P16070-18;P16070-6 P16070 CD44 CD44 antigen 1 S(1)QEMVHLVNK;S(1)QEMVHLVNK;S(1)QEMVHLVNK;S(1)QEMVHLVNK;S(1)QEMVHLVNK 107.53 0.001497 350877500.0 337492.0 910412.0 827197.0 538586.0 759771.0 725498.0 1188809.0 1301192.0 1079800.0 687691.0 True False 444807.4357303101 1204684.874922998 816227.8272990825 414423.31877075066 654289.9112520905 680132.4953711145 1294610.6979718115 1100122.6748175737 1136876.0235446105 663615.1474068484 0.6702792084666025 1.8153366143470973 1.229971664282507 0.6244934588822405 0.9859478250440826 1.02488995018997 1.9508456113918586 1.657772097452007 1.7131556264004564 1.0 19.339987291470997 -7.243081184737902 24.214038170475888 1.6352576791751545 1.0776592994486136 0.3046967294864148 0.3820475730144146 652.0745625371798 860072.3022861093 0.14733462352599655 0.11388055786169332 5.713718174303455e-08 7.243081184737902 -0.5575983797265409 S(ph)QEMVHLVNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SQEMVHLVNK 10 0 P16070;P16070-5;P16070-7;P16070-3;P16070-4;P16070-8;P16070-17;H0Y2P0;H0YD13;H0YE40;P16070-10;P16070-16;P16070-11;P16070-13;P16070-14;P16070-12;P16070-18;P16070-6 P16070 CD44 CD44 antigen 1 S(1)QEMVHLVNK;S(1)QEMVHLVNK;S(1)QEMVHLVNK;S(1)QEMVHLVNK;S(1)QEMVHLVNK 101.38 0.0025131 436447000.0 407845.0 636289.0 732124.0 531083.0 1386980.0 579701.0 669887.0 562650.0 568182.0 616459.0 True False 476885.1031940696 699455.5668324962 749580.6127557307 501328.14130431786 1115211.2255192387 549300.4590547137 606430.4537981127 547881.0336769538 576490.586855261 728218.1368132395 0.6548657319645591 0.9605028101790881 1.0293352703847445 0.6884312762356942 1.5314246777751546 0.754307578026704 0.8327593383651735 0.7523584019405776 0.791645466807577 1.0 19.474011147057574 -11.094499652364387 6.151585364523396 1.0002359864286008 0.8981179708219105 0.017462378631159958 0.24142552070935525 0.0007727117094139117 5.3809515481104226e-05 0.23116772053976775 0.05593746211165784 8.04452392484303e-12 11.094499652364387 -0.10211801560669032 S(ph)QEMVHLVNK ddPTM_PC-9_Lapatinib_30min_R1 9 SQEMVHLVNK 10 0 P16070;P16070-5;P16070-7;P16070-3;P16070-4;P16070-8;P16070-17;H0Y2P0;H0YD13;H0YE40;P16070-10;P16070-16;P16070-11;P16070-13;P16070-14;P16070-12;P16070-18;P16070-6 P16070 CD44 CD44 antigen 1 S(1)QEMVHLVNK;S(1)QEMVHLVNK;S(1)QEMVHLVNK;S(1)QEMVHLVNK;S(1)QEMVHLVNK;S(1)QEMVHLVNK;S(1)QEMVHLVNK;S(1)QEMVHLVNK;S(1)QEMVHLVNK 102.73 0.0017586 221495700.0 1488904.0 2714830.0 747243.0 535559.0 1043922.0 564446.0 507072.0 513099.0 1157195.0 328268.0 True False 1467671.955928447 2708543.977933652 685807.5649813947 574945.795432452 982520.5603896185 540305.960367891 533325.7070376485 536939.4526999923 1026859.5132964287 385008.6864103848 3.8120489426153883 7.035020438594953 1.7812781612163038 1.4933320097085063 2.55194387833198 1.4033604420861643 1.3852303230093128 1.3946164636079483 2.6671073914469776 1.0 18.554531470114 -5.278590091912376 24.6200103884666 1.7235386256127672 5.423534458876734 0.7419443866873453 0.8760904402928898 254.16515554439806 364856.41000407556 0.21151582239679242 0.4421348417931834 5.265139812429907e-06 5.278590091912376 3.6999958332639666 S(ph)QENILQGFSTSHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQENILQGFSTSHK 14 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 S(1)QENILQGFSTSHK;S(1)QENILQGFSTSHK 162.81 0.00019993 7682000.0 10843.5 17177.9 41563.0 57057.0 77437.0 75901.0 56729.0 52050.0 64306.0 41757.0 True False 12679.090381112654 18883.208387213865 42554.01954855527 53860.28127128986 62263.77573615576 71920.617943926 51355.2184376068 50683.74265153364 65246.353595000335 49327.2135517699 0.2570404745811497 0.3828152256643396 0.8626884935208021 1.0918979077292175 1.262260145118651 1.4580312319576672 1.0411133072357406 1.0275006229236938 1.3227253051000536 1.0 15.590096172687977 -5.3770766053336985 1.7338479835461784 1.19126807860241 0.23096870202813927 0.8630411931689136 0.1353063069438926 0.1435447840468789 0.7833337215327495 0.04166343085207541 0.15194110505169547 4.196849491078475e-06 5.3770766053336985 -0.9602993765742707 down S(ph)QEPSPVGSR ddPTM_PC-9_AZD4547_30min_R2 1 SQEPSPVGSR 10 0 M0QZ12;Q96CP6-2;Q96CP6-3;Q96CP6 M0QZ12 GRAMD1A GRAM domain-containing protein 1A 1 S(0.5)QEPS(0.495)PVGS(0.005)R 72.73100000000001 0.029798 3931900.0 15732.0 14752.0 23659.0 30257.0 22124.0 16229.0 22959.0 25510.0 21915.0 18462.0 True False 20734.448754071964 19520.295508916945 23345.266201484028 23281.71611599004 19052.464488038142 15214.198064471364 25002.306522523602 21568.015661482914 23073.382159640783 17815.65099939545 1.1638333482607826 1.0956824148373439 1.3103796320592618 1.3068125389737413 1.0694228624418307 0.8539793502346694 1.403390003731664 1.2106218101272188 1.2951186661898433 1.0 14.120857581316466 -10.17419758861741 15.471055663834324 1.0000052658725167 1.1875885439110234 0.12728858809141663 0.14907206620619146 0.0 0.0 0.1496347401011583 0.036291755217583675 6.69579904949941e-11 10.17419758861741 0.18758327803850672 S(ph)QEQEVLER ddPTM_PC-9_Lapatinib_30min_R1 1 SQEQEVLER 9 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 S(1)QEQEVLER 114.72 0.00085856 0.0 13100.0 5771.9 10988.0 6964.4 11646.0 8685.3 6749.7 1945.1 10848.0 6656.9 True False 12913.191597754225 5758.535520174479 10084.609054906585 7476.585208557346 10961.00517691695 8313.849965423175 7099.1664394642585 2035.4764469366605 9626.18400549576 7807.536295238312 1.6539393618483424 0.7375611591695724 1.29165061468328 0.9576113290843351 1.4039006368246902 1.0648493520924975 0.9092710134173726 0.2607066262603306 1.2329349030841663 1.0 12.930651655643588 -7.267963353342605 3.4731229564044606 0.7788154707499149 1.1746999371792983 0.19672441678668384 0.32728654380173544 0.34795182561848426 9.023709187450748 0.13351764213775671 0.0921137805172061 5.3955614944664856e-08 7.267963353342605 0.39588446642938346 S(ph)QERDNLGMLVWSPNQNLSEAK ddPTM_PC-9_AZD4547_30min_R2 2 SQERDNLGMLVWSPNQNLSEAK 22 1 Q9UKL0 Q9UKL0 RCOR1 REST corepressor 1 1 S(0.996)QERDNLGMLVWS(0.004)PNQNLSEAK;S(1)QERDNLGMLVWSPNQNLSEAK 70.352 0.0027869 11150600.0 18144.2 18902.3 25655.0 30546.0 26393.5 22045.6 19482.9 29033.0 23267.7 24868.0 True False 23913.67817719504 25012.098820376952 25314.797937320785 23504.09163099553 22729.218109972633 20667.085146965903 21216.84035662158 24546.616961969175 24497.583120049003 23997.37888923009 0.9965120894068721 1.0422846151586274 1.0548984559593693 0.9794441192718781 0.9471541960848648 0.8612226044504049 0.8841315734754513 1.0228874193000128 1.0208441193985316 1.0 14.55058921579921 -5.9504721516457755 4.231472492952498 0.9496502142036892 1.0318955380804693 0.2891679043071722 0.051999065062257585 0.2761626618876282 10.529933273830972 0.016811125959620702 0.025151277061452978 1.1207992930756256e-06 5.9504721516457755 0.08224532387678007 S(ph)QERDNLGMLVWSPNQNLSEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQERDNLGMLVWSPNQNLSEAK 22 1 Q9UKL0 Q9UKL0 RCOR1 REST corepressor 1 1 S(0.997)QERDNLGMLVWS(0.003)PNQNLSEAK;S(1)QERDNLGMLVWSPNQNLSEAK 75.358 0.0013457 10301000.0 29552.1 25320.9 27859.5 38191.0 44546.0 39063.0 40856.0 41232.0 35153.0 29528.8 True False 34554.68684941941 27834.59161200168 28523.776137742105 36051.2820868926 35817.53107613665 37014.46751351864 36985.82390817507 40149.70368891515 35667.04612205777 34882.13769014782 0.9906126498428193 0.7979611759821513 0.817718695772433 1.0335169939162012 1.0268158274672776 1.061129562709486 1.0603084087538999 1.1510104124224907 1.0225017296497754 1.0 15.090200835388872 -5.8283833965189595 5.887640708341641 1.058551654230118 0.8620601782471088 0.6504429466467037 0.061018481306541514 0.1118611713418097 7.107142665586442 0.017238062256428655 0.026125227945948296 1.4846244325370115e-06 5.8283833965189595 -0.1964914759830093 S(ph)QERDNLGMLVWSPNQNLSEAK ddPTM_PC-9_Lapatinib_30min_R1 2 SQERDNLGMLVWSPNQNLSEAK 22 1 Q9UKL0 Q9UKL0 RCOR1 REST corepressor 1 1 S(1)QERDNLGMLVWSPNQNLSEAK;S(1)QERDNLGMLVWSPNQNLSEAK 82.62700000000001 0.00050913 7670400.0 29683.4 27665.9 36398.0 26346.0 31139.1 30917.5 24157.4 26785.8 37832.6 25248.1 True False 29260.109272731122 27601.84130833783 33405.49694034311 28283.572727679595 29307.559359826075 29595.23059721265 25408.15196893399 28030.366054370454 33571.49419306038 29612.200444021473 0.988109928812756 0.9321104441568264 1.1280991091321442 0.9551324218930134 0.9897123118300077 0.9994269305706982 0.8580298521538525 0.9465816668152947 1.1337048138831665 1.0 14.853904078836464 S(ph)QESGYYDR ddPTM_PC-9_AZD4547_30min_R2 2 SQESGYYDR 9 0 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 1 S(0.835)QES(0.164)GY(0.001)YDR;S(1)QESGYYDR 100.55 0.0037825000000000003 57804000.0 36658.1 42495.8 59464.4 59409.0 50461.1 51674.3 35166.5 55841.1 51909.6 58064.3 True False 48314.61326415237 56231.73629933791 58675.86320265125 45713.172909900306 43455.44728698885 48443.09785217281 38296.25037346252 47212.14109582258 54653.43548045123 56031.486530397466 0.8622761282255356 1.0035738792836024 1.0471944764631436 0.815847940873398 0.7755540675047764 0.8645692065637434 0.6834773222139402 0.8426001882032823 0.9754057738732556 1.0 15.77395014771248 -5.775606067202911 24.985124029582277 0.8349401583864944 0.9742707374591947 0.23281394698309854 0.09667650678785672 277.6076678292865 489603.12874449545 0.02716037729649482 0.040503883499619434 1.6764628453035963e-06 5.775606067202911 0.1393305790727003 S(ph)QESGYYDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQESGYYDR 9 0 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 1 S(0.963)QES(0.037)GYYDR 127.52 0.0013595999999999999 19281000.0 17510.0 24093.0 21221.0 24385.0 19782.0 22924.0 24734.0 23158.0 24292.0 18631.0 True False 20474.09716173583 26484.793814910077 21726.989121090668 23018.787507236666 15905.8591062752 21721.8250846044 22391.016461347226 22550.127037929233 24647.224544051085 22008.652817085156 0.9302748937836821 1.2033809627070915 0.9872021382528314 1.0458971613822428 0.7227093470222584 0.9869675016065457 1.0173733325451544 1.0246027880645077 1.1198879253943987 1.0 14.425783217936859 -10.527854225287264 15.037299992556106 0.9999999993738882 1.0030300407021102 1.9817535450106227e-05 0.11861133631086014 0.0 0.0 0.11790505316941832 0.028596175765386953 2.965826727954047e-11 10.527854225287264 0.003030041328222044 S(ph)QESGYYDR ddPTM_PC-9_Lapatinib_30min_R1 1 SQESGYYDR 9 0 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 1 S(1)QESGYYDR 85.522 0.012371 21477000.0 0.0 15936.0 0.0 0.0 0.0 0.0 0.0 29074.0 0.0 0.0 True False 0.0 15899.101171104927 0.0 0.0 0.0 0.0 0.0 30424.88417985523 0.0 0.0 0.0 S(ph)QETPEKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQETPEKPR 9 1 J3QQY0;J3KSZ8;Q68DK7;Q68DK7-2;J3KTC2;Q68DK7-3 J3QQY0 MSL1 Male-specific lethal 1 homolog 1 S(0.766)QET(0.234)PEKPR 61.691 0.030569 5550700.0 33380.0 27598.0 28459.0 34713.0 33603.0 39283.0 36975.0 34592.0 34152.0 24739.0 True False 39030.57471494815 30337.747051172024 29137.570491358514 32768.14315106444 27018.733371153856 37222.9303262308 33472.46032418188 33683.99665325362 34651.40839076372 29223.984866183764 1.335566483957223 1.038111236030547 0.9970430324536185 1.1212756679525167 0.9245396716044124 1.2737116617283406 1.1453763228201708 1.1526147719926694 1.185718119874208 1.0 14.834865291253912 -6.7800982690603835 24.999243140037855 1.1606407859338863 1.0781131434158933 0.07353577400962774 0.11807599250756484 589.2783423304419 789511.986555718 0.04048757674563281 0.035765795904844674 1.6592114304208566e-07 6.7800982690603835 -0.08252764251799305 S(ph)QGGEEEGPLSDK ddPTM_PC-9_AZD4547_30min_R2 4 SQGGEEEGPLSDK 13 0 E9PR76;E9PSH4;Q9H063 E9PR76 MAF1 Repressor of RNA polymerase III transcription MAF1 homolog 1 S(1)QGGEEEGPLSDK;S(1)QGGEEEGPLSDK;S(1)QGGEEEGPLSDK;S(1)QGGEEEGPLSDK 219.85 8.3884e-15 101933000.0 140251.0 126969.0 130980.0 150425.0 168448.0 176973.0 170305.0 201954.0 174589.0 176221.0 True False 184847.90059797541 168009.24623587812 129243.11961918848 115746.84029308261 145061.9028241299 165906.85033358124 185461.81507549912 170746.6497412431 183817.41810949234 170051.55642749806 1.0870109305749625 0.9879900529314433 0.7600231502396841 0.6806573413659498 0.8530466046394433 0.9756267676639354 1.0906210973409778 1.0040875445561794 1.0809511066596054 1.0 17.3756126850692 -6.921088966147556 3.83418595579929 1.0435500678957779 0.8635878951236481 0.3539956685857135 0.10819733762050798 0.278209051073764 8.022956068782102 0.044987939124437264 0.03888372603731975 1.1992536083344325e-07 6.921088966147556 -0.17996217277212978 S(ph)QGGEEEGPLSDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SQGGEEEGPLSDK 13 0 E9PR76;E9PSH4;Q9H063 E9PR76 MAF1 Repressor of RNA polymerase III transcription MAF1 homolog 1 S(1)QGGEEEGPLSDK;S(1)QGGEEEGPLSDK;S(1)QGGEEEGPLSDK;S(1)QGGEEEGPLSDK 164.58 0.00010245 74403000.0 76108.0 94054.0 85139.0 102362.0 155476.0 133700.0 194219.0 148425.0 153029.0 139087.0 True False 88991.58119848056 103391.0595387684 87169.03665145548 96626.9890020816 125011.59389380438 126688.53663460171 175821.17029620722 144529.00101928663 155266.75962257484 164302.37208791374 0.5416329665092332 0.629273078805257 0.5305403418327624 0.5881046498244049 0.7608629888003934 0.7710694314675756 1.0701073153230563 0.8796525526847117 0.9450061958904392 1.0 17.325993783542607 -6.700393305997911 1.3918649077361913 0.9638234380327749 0.5683413779010564 0.8808226854246892 0.06440525307061612 0.1300272188161135 0.5263185607226452 0.028407491061147577 0.02708486994808609 1.9934561824169485e-07 6.700393305997911 -0.3954820601317185 S(ph)QGGEEEGPLSDK ddPTM_PC-9_Lapatinib_30min_R1 4 SQGGEEEGPLSDK 13 0 E9PR76;E9PSH4;Q9H063 E9PR76 MAF1 Repressor of RNA polymerase III transcription MAF1 homolog 1 S(1)QGGEEEGPLSDK;S(1)QGGEEEGPLSDK;S(1)QGGEEEGPLSDK;S(1)QGGEEEGPLSDK 170.47 5.9808e-05 78276700.0 48288.1 41051.5 45392.4 57260.0 85130.0 108449.0 101313.0 93292.0 126236.0 98033.0 True False 47599.50283904701 40956.447773946624 41660.41209173112 61471.09141376045 80122.82077201949 103810.88907696649 106558.49141168376 97626.68689919039 112017.97235598846 114977.8734292383 0.41398837375733455 0.35621156099353984 0.3623341678637891 0.5346340959383986 0.6968542588442469 0.9028771013133723 0.9267738933897038 0.8490910815051169 0.9742567766738922 1.0 16.810996727212817 -6.356761198862349 1.3913641496835085 0.9328722079210855 0.3680674820499213 0.9682222991684994 0.04443609527093307 0.06520740954206014 0.25566144495096815 0.017355426135143993 0.022307830229171467 4.3978336822299913e-07 6.356761198862349 -0.5648047258711641 down S(ph)QGSGNEAEPLGK ddPTM_PC-9_Lapatinib_30min_R1 1 SQGSGNEAEPLGK 13 0 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;Q9NUQ6-2 B8ZZZ7 SPATS2L SPATS2-like protein 1 S(0.937)QGS(0.063)GNEAEPLGK 125.73 0.00013799 46536000.0 70849.0 106910.0 87125.0 67035.0 67501.0 79735.0 72973.0 99028.0 59344.0 55349.0 True False 69838.68026788475 106662.45646353105 79961.91881222562 71964.97752220456 63530.72389207201 76324.91992136327 76751.18488036876 103629.2023994878 52660.053799976085 64916.000902093365 1.0758315253155504 1.643084216238149 1.2317751817895342 1.1085861193258422 0.9786604690558398 1.1757489503470322 1.1823153585219348 1.596358385597133 0.8112029864470277 1.0 15.986286506107756 -1.5228787608492165 0.02555991273841433 0.011632817036998408 2.827341192025297 0.09839498635193056 0.23555282194935462 4903.873806274869 9.671167524269832 363.52613443268 772.4477775764354 0.029999998924539965 1.5228787608492165 2.8157083749882985 S(ph)QLDSLKR ddPTM_PC-9_Lapatinib_30min_R1 1 SQLDSLKR 8 1 Q14693;Q14693-2;Q14693-4;Q14693-3;Q14693-5;Q14693-7;A0A0A0MS66;Q14693-6 Q14693 LPIN1 Phosphatidate phosphatase LPIN1 1 S(0.999)QLDS(0.001)LKR 60.167 0.032488 6496500.0 21607.0 28494.0 25940.0 24631.0 35345.0 33684.0 36518.0 37264.0 35559.0 31300.0 True False 21298.880217761478 28428.02389366616 23807.313331295663 26442.44590660731 33266.07659094362 32243.413841239133 38408.72335605368 38995.4214789202 31553.970967129753 36710.16329537161 0.5801902880788009 0.7743911043089896 0.6485210414277093 0.720303140409652 0.9061816566514098 0.8783239012533719 1.0462694771204197 1.062251376142386 0.8595431928004541 1.0 15.163891911445337 -6.395490227460836 1.3782891772755594 0.9897615169188743 0.6682723014804111 0.7805338576842612 0.07347599199552887 0.1894776453476027 0.7322958435012976 0.029095843096916676 0.03621541014282326 4.0226270765372264e-07 6.395490227460836 -0.3214892154384632 S(ph)QMEEVQDELIHR ddPTM_PC-9_AZD4547_30min_R2 4 SQMEEVQDELIHR 13 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 S(1)QMEEVQDELIHR;S(1)QMEEVQDELIHR;S(1)QMEEVQDELIHR;S(1)QMEEVQDELIHR 168.08 5.739999999999999e-05 29996760.0 30130.7 33175.9 42077.700000000004 47061.2 48447.1 42281.1 31684.0 66737.7 39523.9 46275.5 True False 39711.63584250672 43899.36088491579 41519.72220491924 36211.967428292 41721.05642281828 39637.25613307782 34503.81461995895 56424.9219447804 41613.052664358926 44655.40883016599 0.8892906118839605 0.9830692862285595 0.9297803623929987 0.8109200738932615 0.9342889812406001 0.8876249746996323 0.7726682057975169 1.2635629909777866 0.9318703770605306 1.0 15.446547310099898 -7.746954345112094 24.999999338145344 1.0732876083476905 0.8911004470182902 0.4145386342556414 0.0968838809375848 206.30391393716408 356065.1014217978 0.0436365179545093 0.02504938820559362 1.7907941000528153e-08 7.746954345112094 -0.18218716132940038 S(ph)QMEEVQDELIHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SQMEEVQDELIHR 13 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 S(1)QMEEVQDELIHR;S(1)QMEEVQDELIHR;S(1)QMEEVQDELIHR;S(1)QMEEVQDELIHR 167.55 3.0183000000000002e-05 31780600.0 63440.8 90513.8 74839.6 61386.6 75537.4 43548.8 50092.9 63854.4 37745.1 36660.4 True False 74180.07442708452 99499.41187913512 76624.0598947637 57947.30782004245 60736.388719762996 41265.024264719075 45347.73787081026 62178.28965932929 38297.05068078635 43306.64031643329 1.7129030071385125 2.2975555515762034 1.7693374349727073 1.3380698063075922 1.402472883511025 0.9528567435202427 1.0471312837814957 1.4357680301451345 0.8843228290386225 1.0 15.402300633533589 -5.82859933183528 1.6056951316536203 1.1175868750994995 2.0294582200383773 0.7458677834117114 0.21345427606899 0.1823161352387267 0.9571198447639775 0.06762406353136263 0.13745679492886198 1.483886446735648e-06 5.82859933183528 0.9118713449388778 S(ph)QMEEVQDELIHR ddPTM_PC-9_Lapatinib_30min_R1 6 SQMEEVQDELIHR 13 0 A0A2R8YE63;Q12929;A0A2R8Y4W2;Q12929-2 A0A2R8YE63 EPS8 Epidermal growth factor receptor kinase substrate 8 1 S(1)QMEEVQDELIHR;S(1)QMEEVQDELIHR;S(1)QMEEVQDELIHR;S(1)QMEEVQDELIHR;S(1)QMEEVQDELIHR;S(1)QMEEVQDELIHR 207.43 4.3181999999999996e-10 18463050.0 38057.0 55588.24999999999 61392.299999999996 56805.3 51647.99999999999 47944.72 43989.5 43014.5 65411.600000000006 65111.52 True False 37514.30020120093 55459.53882245691 56344.862075131176 60982.95125892575 48610.16618387483 45894.23609020113 46267.061067723414 45013.110702152575 58044.25679331546 76365.95947635302 0.4912437486340673 0.7262337722559506 0.7378269383569855 0.7985619728618656 0.636542335317965 0.6009776660294884 0.6058597493566511 0.589439470292926 0.7600802398258226 1.0 16.220642072279468 -8.600476840212803 4.632040435699686 0.999950818279572 0.6561011193031985 0.62137847025721 0.08338860997805697 0.30994938915779935 16.679011592047175 0.08517670529245325 0.02219799726004534 2.5091299812275976e-09 8.600476840212803 -0.3438496989763735 S(ph)QNINRKEVKS(ph)QDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQNINRKEVKSQDK 14 3 A0A087WTW5;Q9UKL3 A0A087WTW5 CASP8AP2 CASP8-associated protein 2 2 S(1)QNINRKEVKS(1)QDK 51.211000000000006 0.037829 3717100.0 19204.0 15359.0 17614.0 25864.0 25145.0 29497.0 22485.0 23837.0 19245.0 20489.0 True False 22454.85790371074 16883.740015905187 18033.98456146698 24414.923932219364 20218.01775489281 27950.125393499202 20355.05802269719 23211.30400738918 19526.42171703701 24203.493509165248 0.9277527599562293 0.697574505494909 0.7450984112949631 1.0087355332805181 0.8353346903097588 1.1547971528537895 0.840996693927232 0.9590063516491802 0.8067604666096178 1.0 14.562927679305153 -5.754670654342541 24.999944672691196 0.9419594841261959 0.7808851260492298 0.2856964775759492 0.11092826592215733 190.7544862532361 704533.2593680922 0.02903875700913883 0.04887780596991407 1.7592572346144114e-06 5.754670654342541 -0.16107435807696613 S(ph)QPCDLDAR ddPTM_PC-9_AZD4547_30min_R2 1 SQPCDLDAR 9 0 Q9NYF3 Q9NYF3 FAM53C Protein FAM53C 1 S(1)QPCDLDAR 92.792 0.006755199999999999 13381000.0 21836.0 25187.0 28391.0 30883.0 28868.0 24854.0 22860.0 34896.0 33039.0 30399.0 True False 28779.39378298469 33328.20519137006 28014.516789650155 23763.40148759365 24860.17649795177 23299.875451005668 24894.49571431202 29503.625030306062 34785.37408954466 29334.740262735493 0.9810686416591092 1.1361343203610208 0.9549945402188393 0.8100771056691705 0.8474653695683867 0.7942758395786433 0.8486352867400703 1.0057571591245724 1.1858081502679338 1.0 14.840322597625802 -10.218846844436108 11.230884906239567 0.9999995510508402 0.9438229371974627 0.009739476535289615 0.12628782918249465 0.0 0.0 0.13455319213136865 0.032633942554215305 6.041616516655516e-11 10.218846844436108 -0.056176613853377466 S(ph)QPCDLDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQPCDLDAR 9 0 Q9NYF3 Q9NYF3 FAM53C Protein FAM53C 1 S(1)QPCDLDAR 68.676 0.042418 7650300.0 19864.0 38812.0 31301.0 36424.0 34872.0 37580.0 33387.0 34642.0 25695.0 16358.0 True False 23226.58286811654 42664.99886042789 32047.33454970356 34383.281368201286 28039.08193074657 35609.238644190955 30224.341659052312 33732.68420623302 26070.740764835846 19323.575910143238 1.2019816092074633 2.2079246128576226 1.658457766757416 1.7793436125946533 1.4510296676521675 1.8427872154604223 1.5641174179975197 1.7456750429161623 1.3491675084398287 1.0 14.238074475299648 -8.517309012116806 2.6506079668214864 1.0009539724558594 1.696221541991401 0.42991892451570346 0.24883660699389282 0.22915019653574842 3.832943681555321 0.22145264503378417 0.059807990117178356 3.0387221243802547e-09 8.517309012116806 0.6952675695355417 S(ph)QPCDLDAR ddPTM_PC-9_Lapatinib_30min_R1 2 SQPCDLDAR 9 0 Q9NYF3 Q9NYF3 FAM53C Protein FAM53C 1 S(1)QPCDLDAR;S(1)QPCDLDAR 87.719 0.010673 17654600.0 26614.0 38046.0 42524.0 35609.0 39507.0 34267.0 32342.0 33585.0 47952.0 35621.0 True False 26234.479479590133 37957.90682453929 39027.84086738696 38227.80464814175 37183.275933750454 32801.48029027849 34016.51050937861 35145.48170807039 42551.14080305428 41778.042388001035 0.6279489889915204 0.9085611640683549 0.9341711252271612 0.9150214433963296 0.8900195846521944 0.7851368425941211 0.8142198285276384 0.8412429041472855 1.0185048980484372 1.0 15.3504572725459 -14.522878745280336 0.02061197548561626 2.1232460407263862 7.92574745006468e-11 0.2801129839370682 0.09161572658683732 5199.77805376614 8.081638372130579 566.6121424633535 303.6838552304952 3.0000000000000132e-15 14.522878745280336 -2.1232460406471287 S(ph)QPKAPPVDDAEVDELVLQTK ddPTM_PC-9_AZD4547_30min_R2 1 SQPKAPPVDDAEVDELVLQTK 21 1 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 S(1)QPKAPPVDDAEVDELVLQTK 78.428 0.0005199 2475700.0 2385.4 4093.6 7665.9 12313.0 9473.7 8763.2 5217.2 8648.2 5762.3 8466.4 True False 3143.9075805977127 5416.7761452889345 7564.245157189919 9474.428083953642 8158.44028296542 8215.235718687249 5681.520692944386 7311.8194058657955 6066.883414031393 8169.9939129715995 0.38481149607787246 0.663008590090704 0.925856890196708 1.1596615841917552 0.9985858459468574 1.00553755684491 0.6954130876307956 0.8949602023884902 0.7425811424900731 1.0 12.99611928815802 -4.972457004479113 2.4739360951330154 0.9290636722829501 0.36258637659122855 0.6494351768877817 0.12687076529796787 0.24239096820011402 2.489586025474324 0.036830145214830204 0.24641473843067738 1.0654743413068936e-05 4.972457004479113 -0.5664772956917214 S(ph)QPKAPPVDDAEVDELVLQTK ddPTM_PC-9_Lapatinib_30min_R1 1 SQPKAPPVDDAEVDELVLQTK 21 1 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 S(1)QPKAPPVDDAEVDELVLQTK 70.704 0.0012504 1500900.0 12910.0 8519.3 12547.0 7454.2 6737.2 10264.0 8607.1 5114.6 9381.6 5967.3 True False 12725.90103259595 8499.574084274227 11515.434092820611 8002.406734482244 6340.931141844832 9825.03264655261 9052.733523136254 5352.242987765274 8324.945415372329 6998.739854072554 1.8183131960806873 1.2144434943282454 1.6453582120386716 1.1434067991290828 0.9060104067384439 1.403828810815913 1.2934804996171538 0.764743810937738 1.1894920498478105 1.0 12.772879468156908 -1.5228787453226191 0.35130720309413976 1.0353563904795071 9.097816711373579 0.46855082748374055 0.22302920980455654 58.401540896085024 0.821282216039243 0.18929181298423411 312.2799811771332 0.029999999997079294 1.5228787453226191 8.062460320894072 S(ph)QQQPTPVTPK ddPTM_PC-9_Lapatinib_30min_R1 1 SQQQPTPVTPK 11 0 O95251-2;O95251-4;O95251 O95251-2 KAT7 Histone acetyltransferase KAT7 1 S(0.994)QQQPT(0.003)PVT(0.002)PK 86.13600000000001 0.011082999999999999 6788000.0 27240.0 23643.0 24792.0 24900.0 25810.0 22590.0 22974.0 23141.0 27752.0 20008.0 True False 26851.552604795805 23588.256086121593 22753.697459887528 26731.229063964987 24291.906544412384 21623.87835986199 24163.481307354672 24216.215340373892 24626.27751848435 23466.35614101582 1.1442574400319079 1.0051946686725983 0.9696306202443306 1.1391299485667754 1.0351801702162706 0.9214842828566193 1.0297074314456678 1.0319546500893433 1.0494291218669929 1.0 14.518306216918964 -6.5270898837409055 24.961291225343512 1.0064473928837085 1.057735845182899 0.17298305333127195 0.05910454285620906 247.97669946882672 1469856.9931329493 0.019912246314557056 0.019986950775721136 2.971051064631471e-07 6.5270898837409055 0.051288452299190546 S(ph)QRYSGAYGASVSDEELK ddPTM_PC-9_Lapatinib_30min_R1 2 SQRYSGAYGASVSDEELK 18 1 A0A286YEX5;C9JRZ6;F8WAR4;Q9NX63 A0A286YEX5 CHCHD3 MICOS complex subunit MIC19 1 S(0.945)QRY(0.018)S(0.037)GAYGASVSDEELK;S(0.731)QRY(0.084)S(0.183)GAY(0.001)GASVSDEELK 109.28 0.0012181 15055600.0 304200.0 152412.0 115643.0 97299.0 106435.0 120139.0 94990.0 82681.0 121066.0 81480.0 True False 299862.05221655173 152059.09937816515 106135.27893488928 104454.69303994908 100174.70255926125 115000.93502768752 99908.11741036049 86522.66110183006 107430.27219850206 95563.70943472453 3.1378234895891586 1.5911803788030037 1.110623264445231 1.09303723827608 1.0482504619359327 1.2033954699742972 1.045460855395148 0.9053924508961216 1.1241743631967642 1.0 16.544175234591243 -4.669135198265429 1.9153533330219248 1.0615317234727735 4.238464385062055 0.9851695730686711 0.07652299480138174 0.1252524267350963 0.3833628150243101 0.02181440051452134 0.7851769995248683 2.142223611291562e-05 4.669135198265429 3.176932661589281 up S(ph)QS(ph)KT(ph)TQSGMSK ddPTM_PC-9_AZD4547_30min_R2 1 SQSKTTQSGMSK 12 1 O94986-1;O94986-2 O94986-1 CEP152 Centrosomal protein of 152 kDa 3 S(1)QS(1)KT(0.955)T(0.045)QSGMSK 106.54 0.013356 10075000.0 0.0 0.0 0.0 0.0 860.53 0.0 0.0 1382.5 0.0 0.0 True False 0.0 0.0 0.0 0.0 741.0602633290292 0.0 0.0 1168.8663916895387 0.0 0.0 0.0 S(ph)QSAAVTPSSTTSSTR ddPTM_PC-9_AZD4547_30min_R2 5 SQSAAVTPSSTTSSTR 16 0 Q16186;A0A087WX59 Q16186 ADRM1 Proteasomal ubiquitin receptor ADRM1 1 S(1)QSAAVTPSSTTSSTR;S(1)QSAAVTPSSTTSSTR;S(0.984)QS(0.015)AAVTPS(0.001)STTSSTR;S(0.999)QS(0.001)AAVTPSSTTSSTR;S(1)QSAAVTPSSTTSSTR 180.39 4.1338999999999995e-06 47885500.0 36444.18 30858.9 35444.4 55179.700000000004 50733.1 45309.200000000004 29987.2 47852.9 36940.3 46459.90000000001 True False 48032.6711539648 40833.4359463203 34974.38409704046 42458.87268286668 43689.68478205057 42476.00856138674 32656.002707096122 40458.33385524797 38892.888842882865 44833.35304229296 1.0713602239086113 0.9107825575258806 0.7800974436163147 0.9470376360834232 0.9744906819892877 0.9474198488191938 0.7283863572793787 0.9024159718119259 0.8674989980382186 1.0 15.452284780713438 S(ph)QSAAVTPSSTTSSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SQSAAVTPSSTTSSTR 16 0 Q16186;A0A087WX59 Q16186 ADRM1 Proteasomal ubiquitin receptor ADRM1 1 S(0.578)QS(0.13)AAVT(0.265)PS(0.017)S(0.008)T(0.001)TSSTR;S(1)QSAAVTPSSTTSSTR;S(1)QSAAVTPSSTTSSTR;S(0.995)QS(0.005)AAVTPSSTTSSTR;S(1)QSAAVTPSSTTSSTR 153.34 2.0926e-05 40917000.0 26126.8 27598.899999999998 33089.299999999996 29601.100000000002 31559.899999999998 28886.199999999997 28758.3 28802.000000000004 27271.399999999998 22628.100000000002 True False 30549.551212178172 30338.736397224162 33878.27440386905 27942.64633506102 25375.964149637774 27371.356820751163 26034.105631938324 28045.978018241534 27670.192632580056 26730.395406058957 1.1428768915724132 1.134990183884347 1.267406407171586 1.0453510286917522 0.9493299206447887 1.0239787479741853 0.9739513851724466 1.0492167284545433 1.035158373538615 1.0 14.706193558175753 -5.918570452646145 6.75756834296 1.0062445371285487 1.1760562418710223 0.7712276579309749 0.04303589874097039 0.09934984184918878 6.764540214245585 0.012120396208478842 0.018086650193201236 1.2062283940789368e-06 5.918570452646145 0.16981170474247365 S(ph)QSAAVTPSSTTSSTR ddPTM_PC-9_Lapatinib_30min_R1 4 SQSAAVTPSSTTSSTR 16 0 Q16186;A0A087WX59 Q16186 ADRM1 Proteasomal ubiquitin receptor ADRM1 1 S(1)QSAAVTPSSTTSSTR;S(0.999)QS(0.001)AAVTPSSTTSSTR;S(0.998)QS(0.002)AAVTPSSTTSSTR;S(1)QSAAVTPSSTTSSTR 163.91 5.7787e-05 20436500.0 11527.9 10762.4 14768.200000000003 11478.899999999998 9588.2 10664.5 10301.7 9543.15 12859.3 7738.25 True False 11363.510032042055 10737.480324039887 13554.015602900567 12323.096598487864 9024.240927126488 10208.40419516371 10835.071619394776 9986.559587981896 11410.950219567803 9075.796201930012 1.2520675629126126 1.183089624881232 1.493424411625532 1.3577978531368187 0.9943194763680832 1.1247943395856381 1.193842543212974 1.1003507974163418 1.2572946731815342 1.0 13.14780849814942 -6.244049190578951 24.925996747442603 1.121539655245798 1.3239751861100721 0.4886542201628158 0.10485706100912 744.5621823243417 1067208.320653104 0.031771717481201174 0.04091277174547239 5.700996960000967e-07 6.244049190578951 0.20243553086427424 S(ph)QSASYYPVCHSK ddPTM_PC-9_AZD4547_30min_R2 4 SQSASYYPVCHSK 13 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 S(0.394)QS(0.211)AS(0.394)YYPVCHSK;S(0.572)QS(0.289)AS(0.134)YYPVCHS(0.004)K;S(0.595)QS(0.377)AS(0.027)YYPVCHSK;S(0.616)QS(0.304)AS(0.079)YYPVCHSK 103.39 0.00085548 18399100.0 100228.0 97258.0 135137.0 212654.0 176208.0 137118.0 140245.0 210594.0 168839.0 166268.0 True False 132098.4191280905 128694.74651615006 133344.99508305275 163629.90577154866 151744.56077148012 128543.9897839782 152726.53330943512 178051.5362686924 177763.4848483499 160447.00792804084 0.823314942634116 0.8021012555987868 0.831084336224312 1.0198376889953307 0.9457612375017694 0.8011616510893685 0.9518814671690962 1.1097217615210815 1.1079264558680668 1.0 17.29173736042533 -7.5948596593236495 4.242784108147528 1.079847553477967 0.8755797904076159 0.6192195064009651 0.07060530011613741 0.15311113819372826 5.374762098822176 0.03816889394884548 0.021289959529482923 2.5417939442857915e-08 7.5948596593236495 -0.2042677630703511 S(ph)QSASYYPVCHSK ddPTM_PC-9_Lapatinib_30min_R1 3 SQSASYYPVCHSK 13 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 S(0.88)QS(0.116)AS(0.004)YYPVCHSK;S(0.553)QS(0.319)AS(0.128)YYPVCHSK;S(0.629)QS(0.358)AS(0.012)YYPVCHSK 119.68 0.00012707 14656800.0 121095.0 85432.0 109249.0 104015.0 117981.0 96630.0 115673.0 96620.0 134056.0 129788.0 True False 119368.16309389664 85234.18745292652 100266.96893333545 111664.61008386804 111041.5895395705 92497.3601555318 121661.98194766411 101109.31792865157 118957.20160773786 152221.68286836045 0.7841731929683424 0.5599346022644885 0.6586904509526751 0.7335657311083225 0.7294728809140678 0.6076490445551206 0.7992421293415602 0.6642241500909547 0.7814734364131992 1.0 17.215814349300743 -10.216039156584985 0.36616941279229526 1.1100331683956135 0.6693896080542486 0.6269469552991181 0.07137548526572847 6.523305757392438 0.7764436718366848 0.8823516779290672 0.053131415453762786 6.080801734662514e-11 10.216039156584985 -0.44064356034136487 S(ph)QSESSDEVTELDLSHGK ddPTM_PC-9_Lapatinib_30min_R1 1 SQSESSDEVTELDLSHGK 18 0 Q86YS7-3;Q86YS7;Q86YS7-2;Q86YS7-4;Q86YS7-5 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 S(0.643)QS(0.329)ES(0.014)S(0.014)DEVTELDLSHGK 201.13 2.3829e-15 7131700.0 19789.0 33099.0 36350.0 30538.0 44371.0 37314.0 41904.0 43175.0 42603.0 37368.0 True False 19506.805231141847 33022.3612990965 33361.443315057746 32783.86639178166 41761.185016742405 35718.16720318241 44073.58408215332 45181.06811808664 37804.601510521345 43827.00901026985 0.44508639014291107 0.7534705663203817 0.7612073939894064 0.748028832725033 0.952864134692756 0.8149807164530137 1.0056260985509116 1.0308955399511632 0.8625868468839091 1.0 15.419532604538187 -4.349993122780599 0.45438911120362163 0.9761156160692588 2.1588144549415234e-18 0.7823212318260365 0.07826473343639664 3.368795078754616 0.4025182436315227 0.052860353064059284 1.9173491842472967 4.466906656126741e-05 4.349993122780599 -0.9761156160692588 down S(ph)QSFAGVLGSHER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSFAGVLGSHER 13 0 H3BSV5;A0A0A0MTL6;Q6ZS17-2;Q6ZS17;Q6ZS17-3;Q6ZS17-4;H3BS40;H3BUP6;H3BQI5;H3BU12;H3BMG9;H3BV02 H3BSV5 FAM65A Protein FAM65A 1 S(0.624)QS(0.376)FAGVLGSHER 79.332 0.0079316 15621000.0 24055.0 25008.0 31139.0 32953.0 38926.0 29965.0 32347.0 29295.0 29922.0 25137.0 True False 28127.03639209343 27490.628967885717 31881.471855315136 31106.75024506747 31298.729732629086 28393.582649632302 29282.857988000287 28526.037290618213 30359.552643137486 29694.139115617494 0.9472251841542746 0.9257930954269407 1.0736621031908355 1.0475720519779952 1.0540372836122285 0.9562015769872524 0.9861494173642874 0.9606622094531468 1.0224089179662401 1.0 14.85789058656106 -5.231395232700635 24.98358068712291 1.010953692097465 0.9365091113211005 0.4018459010904253 0.03708449845046718 772.8571994757975 642676.5062553203 0.010403161943064024 0.027517783499125988 5.869549469829101e-06 5.231395232700635 -0.07444458077636462 S(ph)QSFNNYDK ddPTM_PC-9_AZD4547_30min_R2 1 SQSFNNYDK 9 0 Q8IVL1-4;Q8IVL1-11;A0A0A0MTL4;A0A0A0MTE8;Q8IVL1-8;Q8IVL1-9;Q8IVL1-10;Q8IVL1-13;Q8IVL1-12;Q8IVL1-3;Q8IVL1-2;Q8IVL1 Q8IVL1-4 NAV2 Neuron navigator 2 1 S(0.926)QS(0.074)FNNYDK 105.36 0.0026414999999999998 5476400.0 13253.0 14389.0 14610.0 22021.0 20669.0 18612.0 14986.0 21981.0 19174.0 17975.0 True False 17467.17832047518 19039.962857768838 14416.261853995587 16944.398671058494 17799.46612290997 17448.188697759615 16319.724968271215 18584.34152313038 20187.498495503183 17345.700721164187 1.0070033261419513 1.0976762002204623 0.8311144119075989 0.9768644659240519 1.0261601078584346 1.005908552109998 0.940851293966975 1.0714090956530156 1.163832976252819 1.0 14.082290502475788 -7.884541976039732 6.152852532900502 1.0930255271693985 0.9846811908393425 0.2536233394820342 0.07398894305059665 0.2701421681977077 13.339016513821953 0.04119932043594241 0.019496101491057127 1.3045418741343139e-08 7.884541976039732 -0.10834433633005602 S(ph)QSFSHQQPSR ddPTM_PC-9_AZD4547_30min_R2 2 SQSFSHQQPSR 11 0 B3KNS5;Q8WVR3-2;Q8WVR3-3;Q8WVR3 B3KNS5 C7orf43 Uncharacterized protein C7orf43 1 S(0.864)QS(0.132)FS(0.004)HQQPSR;S(0.917)QS(0.082)FS(0.001)HQQPSR 110.44 0.0010974000000000001 51374000.0 37345.0 25830.0 71645.0 113769.0 90893.0 77504.0 54538.0 93090.0 60556.0 76206.0 True False 49219.93317574477 34179.04236681973 70694.94048798856 87541.31476352816 78274.07587738422 72657.66262793694 59391.776345894505 78705.07949539175 63756.86653247582 73538.05113530104 0.6693124500292522 0.4647803666150258 0.9613382377773174 1.1904220116258293 1.064402369507583 0.9880281229408121 0.8076332650782503 1.070263330076344 0.866991517291789 1.0 16.166203323092397 -5.304881253591645 7.357734251451701 0.999752863992499 0.567457482490232 0.7039769327214513 0.1106285157305794 0.11959287737996856 17.781878865915672 0.029719386286983604 0.06315741022444957 4.955856771556897e-06 5.304881253591645 -0.432295381502267 S(ph)QSFSHQQPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQSFSHQQPSR 11 0 B3KNS5;Q8WVR3-2;Q8WVR3-3;Q8WVR3 B3KNS5 C7orf43 Uncharacterized protein C7orf43 1 S(0.955)QS(0.044)FS(0.001)HQQPSR;S(0.723)QS(0.274)FS(0.002)HQQPSR 102.63 0.001836 33867000.0 47537.0 55318.0 86769.0 82193.0 92962.0 93864.0 74837.0 80806.0 81910.0 56787.0 True False 55584.07520145267 60809.60545607415 88837.90203326508 77587.99268330129 74746.76343330066 88941.60660187162 67747.8975870399 78684.9281210341 83107.77879150417 67082.03357435532 0.8285985418113774 0.9064961542746217 1.324317366360026 1.1566136050020146 1.1142590564200707 1.3258633029257623 1.0099261154918109 1.172965754441804 1.238897725117196 1.0 16.033638804038592 -5.119881039699681 5.724385753047147 1.171076116967156 0.8475954462666098 0.5674348703439754 0.10563476902265999 0.14145895660276173 5.925756953510045 0.025707949357613325 0.07156404580260345 7.587853901873629e-06 5.119881039699681 -0.3234806707005462 S(ph)QSFSHSIQNSFLPPSSITR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSFSHSIQNSFLPPSSITR 20 0 Q9H7U1-3;Q9H7U1-2;Q9H7U1 Q9H7U1-3 CCSER2 Serine-rich coiled-coil domain-containing protein 2 1 S(0.414)QS(0.414)FS(0.17)HS(0.002)IQNSFLPPSSITR 62.678000000000004 0.005428199999999999 4391800.0 15759.0 20904.0 24427.0 25301.0 36478.0 26261.0 21056.0 22883.0 24868.0 18359.0 True False 18426.687445562253 22979.210970276843 25009.432319913365 23883.466996948733 29330.39775951404 24883.826930151637 19061.423247761275 22282.345496542643 25231.647454366124 21687.34137023595 0.8496517452734584 1.0595679100534598 1.1531811065710758 1.1012630174082463 1.3524201633939115 1.147389461222877 0.878919316220174 1.027435549436377 1.1634274124994608 1.0 14.404565584838693 -10.632665317583111 14.549458124144685 0.9999979110090245 1.085880693251272 0.029869505571895272 0.137241173749638 0.0 0.0 0.1407827397852231 0.034144829788136516 2.3298860571540012e-11 10.632665317583111 0.08588278224224744 S(ph)QSFTHSPSGDPK ddPTM_PC-9_AZD4547_30min_R2 1 SQSFTHSPSGDPK 13 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 S(0.627)QS(0.164)FT(0.198)HS(0.011)PSGDPK 73.498 0.011983 19978000.0 67900.0 74745.0 156290.0 231820.0 197050.0 156640.0 121940.0 173360.0 128920.0 173300.0 True False 89490.78759226335 98904.85953185984 154217.4924819283 178377.4805832971 169693.0088305869 146845.2760378827 132792.42377091915 146571.1954164905 135734.44800460356 167232.8197484144 0.5351269429463283 0.5914201511440914 0.9221724103793358 1.0666415889635106 1.0147111618752447 0.8780888599426668 0.7940571950571217 0.8764499434799502 0.8116495805596229 1.0 17.351498481196657 -5.236509115302134 5.060030351164939 0.9193247738325776 0.5545103083823837 0.7480747582144285 0.08306162357840569 0.09871632416693947 7.317155580123043 0.024272876160734043 0.0636748304486097 5.800839971518247e-06 5.236509115302134 -0.3648144654501939 S(ph)QSFTHSPSGDPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSFTHSPSGDPK 13 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 S(0.316)QS(0.316)FT(0.316)HS(0.051)PSGDPK 56.339 0.041806 3520800.0 34523.0 34886.0 43863.0 52743.0 64558.0 68018.0 64474.0 64759.0 62176.0 50856.0 True False 40367.06203966913 38349.251526457985 44908.86027135384 49787.980705113136 51908.32333348065 64451.016341154274 58366.55596866264 63059.14486783218 63085.20637456446 60075.79022412551 0.671935598168101 0.6383478499972776 0.7475367382403426 0.8287528223826685 0.8640472832704424 1.0728284405532753 0.9715487012474374 1.0496598485442579 1.0500936590132512 1.0 15.874496099932124 -6.113792138585969 0.9617907276298471 1.036998278027694 0.6426121427906334 0.9281492775064288 0.04143051443888681 0.13390168694128984 0.25703782505681844 0.01802752151143712 0.03410219824091678 7.694986485246735e-07 6.113792138585969 -0.3943861352370607 S(ph)QSIEQESQEK ddPTM_PC-9_AZD4547_30min_R2 2 SQSIEQESQEK 11 0 A0A0A0MRN0;Q5VTL8 A0A0A0MRN0 PRPF38B Pre-mRNA-splicing factor 38B 1 S(1)QSIEQESQEK;S(0.998)QS(0.002)IEQESQEK 157.09 0.00082778 4240700.0 31492.0 32432.0 29083.0 37772.0 38771.0 36161.0 33217.0 37905.0 26864.0 29077.0 True False 41505.800925707736 42915.00975767311 28697.340417505362 29064.248971582656 33388.31588617459 33899.84695356144 36173.24865014443 32047.65322024735 28283.976196057025 28059.02308034998 1.4792318608830923 1.529454879265805 1.0227490934138188 1.0358254059079002 1.1899315165237085 1.2081620538422042 1.2891841795973618 1.142151425888047 1.0080171399789246 1.0 14.776177159652331 -5.254048904090377 24.982233893253298 1.1269041784416072 1.5043434209098288 0.7358222911600953 0.09369428338735239 301.4967279604858 1019151.6577188142 0.02576663477558321 0.06528957523047842 5.5712301010093774e-06 5.254048904090377 0.3774392424682216 S(ph)QSIEQESQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSIEQESQEK 11 0 A0A0A0MRN0;Q5VTL8 A0A0A0MRN0 PRPF38B Pre-mRNA-splicing factor 38B 1 S(0.999)QS(0.001)IEQESQEK 141.34 7.3953e-05 0.0 18704.0 24963.0 21142.0 19778.0 22877.0 19583.0 27958.0 15803.0 17983.0 18083.0 True False 21870.217779160877 27441.16166528038 21646.1054614815 18669.90278114114 18394.416073918597 18556.03300609875 25309.615841608567 15388.187994662556 18245.96735450644 21361.30475505077 1.0238240608401872 1.2846201100516605 1.0133325519998206 0.8740057311680242 0.8611092011862868 0.8686750748083997 1.1848347341996626 0.7203767827442329 0.854159779270612 1.0 14.38271214952213 -5.507254709376913 5.245161995788503 0.9069476979229928 1.1555104295628829 0.37036617230159075 0.12741987672566726 0.1738881632919717 14.4787147583709 0.033978857477155525 0.06709567910568855 3.10989188161165e-06 5.507254709376913 0.24856273163989007 S(ph)QSIEQESQEK ddPTM_PC-9_Lapatinib_30min_R1 2 SQSIEQESQEK 11 0 A0A0A0MRN0;Q5VTL8 A0A0A0MRN0 PRPF38B Pre-mRNA-splicing factor 38B 1 S(0.998)QS(0.002)IEQESQEK;S(0.961)QS(0.039)IEQESQEK 158.52 0.00098782 8620200.0 32484.0 38823.0 36992.0 31355.0 36502.0 36092.0 31825.0 36070.0 37810.0 32308.0 True False 32020.772203163975 38733.10772877803 33950.66055324939 33660.95129721374 34355.02412569316 34548.42929456129 33472.74277907905 37745.94388000888 33551.439643048914 37892.39475229601 0.8450448279261565 1.022186852585533 0.8959755849474841 0.8883300070438046 0.906646949876703 0.9117510128458667 0.8833630863895411 0.9961350853319121 0.8854399375488385 1.0 15.209620698812452 -10.444469522843196 0.4650676817708225 1.0266410805630577 0.9146477463735757 0.1965217877627956 0.05109977293464635 26.713056225394546 3.937449121281404 1.0371565623207937 0.025943946139146714 3.593606144497557e-11 10.444469522843196 -0.11199333418948199 S(ph)QSLNIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSLNIR 7 0 O00443;A0A0C4DGF9;O00443-2 O00443 PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 1 S(0.842)QS(0.158)LNIR 74.376 0.034272000000000004 14579000.0 48283.0 47687.0 42387.0 52963.0 47701.0 41237.0 48022.0 43405.0 40736.0 36844.0 True False 56456.35826728107 52421.05020759622 43397.666833592666 49995.654818362724 38354.33147449363 39074.45912641038 43473.00851082787 42265.66474139901 41331.68693505945 43523.52554305648 1.2971457978841936 1.2044302375214915 0.9971082602364254 1.1487041592920493 0.8812321841104273 0.8977778945723325 0.998839316631677 0.9710992897298012 0.9496401410352497 1.0 15.409507803726763 -4.894591952413794 0.8417257898381506 0.9551277857542495 1.4686094292704222 0.7456074310841019 0.06540665219508998 1.033936219835191 0.6347553562259642 0.024697913143700265 0.4791161935218557 1.274700181322093e-05 4.894591952413794 0.5134816435161726 S(ph)QSLPTTLLSPVR ddPTM_PC-9_AZD4547_30min_R2 5 SQSLPTTLLSPVR 13 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 S(0.577)QS(0.052)LPT(0.1)T(0.271)LLSPVR;S(0.999)QS(0.001)LPTTLLSPVR;S(0.995)QS(0.005)LPTTLLSPVR;S(0.981)QS(0.008)LPT(0.005)T(0.005)LLS(0.001)PVR;S(0.934)QS(0.066)LPTTLLSPVR 174.39 0.00017994 219402600.0 102256.79999999999 78880.20000000001 129766.0 190497.0 164476.0 147414.3 117175.6 135921.0 116466.1 124289.6 True False 134772.3353264291 104376.68206361658 128045.2180524019 146580.85979931126 141641.34646241917 138196.46051730856 127604.0014007849 114917.53260385782 122622.26027574456 119938.25893480994 1.1236809382040633 0.8702534369816761 1.067592769726617 1.2221359647965406 1.1809521642248075 1.15223000354226 1.0639140715736213 0.9581390760917995 1.0223781916193517 1.0 16.87193240984567 -7.583369352338253 5.533622217734082 0.9940238053373163 1.10033232316747 0.22768641320208516 0.08986764359157191 0.3529382030935805 21.61276795206241 0.048503641622504756 0.02764497524647979 2.6099407465102256e-08 7.583369352338253 0.10630851783015371 S(ph)QSLPTTLLSPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SQSLPTTLLSPVR 13 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 S(0.603)QS(0.112)LPT(0.142)T(0.142)LLSPVR;S(0.946)QS(0.054)LPTTLLSPVR;S(0.427)QS(0.184)LPT(0.194)T(0.194)LLSPVR;S(0.999)QS(0.001)LPTTLLSPVR;S(0.554)QS(0.359)LPT(0.025)T(0.063)LLSPVR;S(0.833)QS(0.167)LPTTLLSPVR 178.14 0.00011164 214300600.0 106148.70000000001 106297.2 101220.1 123038.40000000001 135055.6 123817.70000000001 137831.59999999998 122951.7 111992.2 93686.59999999999 True False 124117.57837760997 116849.6835222784 103633.57106336691 116144.95734387469 108592.42468473683 117324.48184339645 124775.19303363065 119724.34815309462 113629.87405657305 110671.23895728249 1.1214980472525258 1.0558270118163284 0.9364092427244624 1.0494592672691139 0.9812163097464911 1.060117180839387 1.1274401028598955 1.0818018238623541 1.0267335499915435 1.0 16.755920820270376 -6.977793053987702 24.724064744724366 1.0698061210759953 1.0258129184648719 0.054854361984636446 0.05548984401581974 460.4532670974563 512643.13127344806 0.019916308646229074 0.0175630467703994 1.0524632644699557e-07 6.977793053987702 -0.04399320261112338 S(ph)QSLPTTLLSPVR ddPTM_PC-9_Lapatinib_30min_R1 6 SQSLPTTLLSPVR 13 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 S(0.999)QS(0.001)LPTTLLSPVR;S(0.301)QS(0.301)LPT(0.199)T(0.199)LLSPVR;S(0.997)QS(0.003)LPTTLLSPVR;S(0.996)QS(0.002)LPT(0.001)T(0.001)LLSPVR;S(0.989)QS(0.011)LPTTLLSPVR;S(0.995)QS(0.005)LPTTLLSPVR 168.45 8.423700000000001e-05 311181400.0 110798.4 93838.5 128684.5 100857.9 107339.29999999999 116136.20000000001 91223.1 103821.6 126328.3 97011.5 True False 109218.39449806197 93621.22271867041 118104.55714653517 108275.32641809159 101025.81341118326 111169.32545270486 95946.18575994356 108645.53055538473 112099.87655802644 113779.80851530159 0.9599101626487078 0.8228280917354491 1.0380098076070499 0.9516216262882027 0.8879063405841194 0.9770567107058749 0.8432619725057835 0.9548753155158776 0.985235236557379 1.0 16.79588503261361 -8.142924989813858 3.9097201264875086 0.9926132984739181 0.9262251788154995 0.16012985569307492 0.06019056627495574 0.43453690154750874 11.111469857103783 0.04494518649831422 0.015238738630854107 7.195732500465387e-09 8.142924989813858 -0.06638811965841862 S(ph)QSNPILGSPFFSHFDGQDSYAAAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSNPILGSPFFSHFDGQDSYAAAVR 26 0 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 S(0.503)QS(0.406)NPILGS(0.09)PFFSHFDGQDSYAAAVR 91.87299999999999 1.7366e-07 1223200.0 0.0 649.91 1210.0 561.42 2418.5 1233.4 1040.2 849.02 2238.8 598.17 True False 0.0 714.4287696944422 1238.8509889505535 529.9654575481984 1944.6122863475157 1168.7183327233925 941.6647256041637 826.7341246110485 2271.5382146065194 706.6134858888853 0.0 1.0110601962198975 1.7532229623273314 0.750007561604245 2.7520169444562588 1.6539711682026585 1.3326447122921738 1.1699948290274382 3.2146827933081905 1.0 9.464777473449022 -4.960600640740424 2.0720921591101362 1.711793172933509 4.249441791147809e-33 0.3446675679194132 0.7250046464045861 0.569420721889856 3.6374632483263083 0.19060118874402468 1.6157889336726454 1.094962786001968e-05 4.960600640740424 -1.711793172933509 S(ph)QSREEQAVLLVR ddPTM_PC-9_AZD4547_30min_R2 1 SQSREEQAVLLVR 13 1 A0A5E8;Q99501 A0A5E8 GAS2L1 GAS2-like protein 1 1 S(0.814)QS(0.186)REEQAVLLVR 58.824 0.03013 2392600.0 1501.4 2573.7 3758.4 4803.7 3980.7 2642.7 3343.4 4527.8 3258.5 3475.0 True False 1978.813968939972 3405.598193553382 3708.561160305067 3696.281181425172 3428.0485168836262 2477.451551234115 3640.956122975976 3828.132548493234 3430.7376576404054 3353.3413077076802 0.5901021659774546 1.0155835273091913 1.1059301216314936 1.1022681088051616 1.0222784388228634 0.7388008925723349 1.0857696216627908 1.1415875084633476 1.023080367559016 1.0 11.711383614759997 -4.761981044711097 6.579606342510047 1.028967467778042 0.5783985463830497 0.6038625106746947 0.10598301487293707 0.08611098161139288 18.17612000517362 0.028175482271256207 0.17413823784143137 1.7298918607141447e-05 4.761981044711097 -0.4505689213949924 S(ph)QSSDLLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQSSDLLER 9 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 S(1)QSSDLLER;S(0.993)QS(0.003)S(0.004)DLLER 96.06700000000001 0.0084708 5990800.0 14282.0 16368.5 9250.3 16917.2 38914.0 40845.0 44693.0 60624.0 56042.0 40176.0 True False 16699.660517641998 17993.456504352107 9470.862233958105 15969.384130302407 31289.081046486353 38703.01629648693 40459.355490700735 59032.68423643759 56861.508228952356 47459.590766958965 0.35187114443616707 0.37913214618106283 0.19955634005490946 0.33648381438257535 0.6592783574583536 0.81549410079262 0.8525011454348286 1.2438515225785667 1.198103635325464 1.0 15.534412040110297 -6.8418432556733375 1.0271791970359216 1.1491116263761996 0.29359846346293117 0.9143469128407522 0.10465570632142482 0.14076117383900894 0.315147806347589 0.06425411648417792 0.05382335199335843 1.4393179590591928e-07 6.8418432556733375 -0.8555131629132684 down S(ph)QSSDLLER ddPTM_PC-9_Lapatinib_30min_R1 2 SQSSDLLER 9 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 S(0.997)QS(0.002)S(0.001)DLLER;S(0.997)QS(0.001)S(0.002)DLLER 101.72 0.0034080999999999994 17163600.0 29118.0 23324.6 30939.0 32939.0 66956.0 64867.0 98083.0 110304.0 105981.0 118239.0 True False 28702.77198041277 23270.59332175914 28395.3148479937 35361.44394128286 63017.779720560844 62092.789622362514 103161.25781619521 115429.12652454965 94044.30375059429 138676.4536064359 0.206976535914823 0.1678049352761871 0.20475945345833307 0.2549924159557665 0.45442306953857825 0.44775293863933086 0.7438988749234033 0.8323628382662407 0.6781562500688995 1.0 17.081363322307183 -7.022283382588676 0.6103516369858627 0.9271819294122277 0.13858766357458882 0.930512975091184 0.0745539038943638 0.18836855971428787 0.14796508983314577 0.06300477812464067 0.055509706376663984 9.499847144494867e-08 7.022283382588676 -0.7885942658376388 down S(ph)QSSGSSATHPISVPGAR ddPTM_PC-9_AZD4547_30min_R2 1 SQSSGSSATHPISVPGAR 18 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 S(0.976)QS(0.003)S(0.003)GS(0.006)S(0.013)AT(0.001)HPISVPGAR 216.16 1.6703000000000002e-27 7369700.0 4581.1 4015.9 11405.0 15244.0 13322.0 11893.0 7389.2 13421.0 7631.2 11823.0 True False 6037.794507200548 5313.961139795252 11253.762248105382 11729.731317452233 11472.47025445869 11149.328829919155 8046.824485222843 11347.092833898947 8034.569652596431 11409.08036864112 0.5292095692301342 0.4657659485335164 0.9863864469775633 1.0281048900043206 1.0055560907425811 0.9772329118273271 0.7053000088719036 0.9945668246046762 0.7042258791234538 1.0 13.477894887120755 -5.259070822159868 24.997934750353952 0.9255314294737912 0.4974877168835532 0.687377004709177 0.11537057054778317 110.75555096111393 1168904.529802482 0.030046015859211177 0.07211308645484768 5.507178812872756e-06 5.259070822159868 -0.428043712590238 S(ph)QSSGSSATHPISVPGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQSSGSSATHPISVPGAR 18 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 S(0.997)QS(0.001)SGS(0.001)SATHPISVPGAR;S(0.999)QS(0.001)SGSSATHPISVPGAR 182.22 2.9174e-09 6310000.0 7045.7 8542.7 13096.5 12182.5 16710.6 13199.9 13307.5 11994.4 11751.599999999999 9590.7 True False 8238.397851081792 9390.762799262535 13408.77022875283 11499.954021197897 13436.27788804582 12507.674006904097 12046.917262043278 11679.559709117297 11923.444918157023 11329.417990060574 0.7271686734754982 0.8288830730317441 1.1835356626895128 1.0150524970732773 1.1859636478973252 1.1039996951191333 1.0633306382209726 1.0309055345441316 1.0524322545622022 1.0 13.46778612910855 -5.114215392886198 4.5702256507105075 1.081644488639145 0.7485660045763125 0.7966202098995213 0.06168409557311435 0.0846699040440434 2.740810616598644 0.015561176082089656 0.046227765249871204 7.687490765866582e-06 5.114215392886198 -0.33307848406283247 S(ph)QSSHSYDDSTLPLIDR ddPTM_PC-9_Lapatinib_30min_R1 1 SQSSHSYDDSTLPLIDR 17 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;H0YC95 O60716 CTNND1 Catenin delta-1 1 S(0.366)QS(0.366)S(0.263)HS(0.005)Y(0.001)DDSTLPLIDR 58.246 0.02428 5125300.0 8571.1 6401.6 11230.0 7874.1 8230.8 7860.0 5421.4 6456.8 14116.0 10452.0 True False 8448.874542252768 6386.777488513134 10306.712749053599 8453.187581227585 7746.680526375409 7523.846122554902 5702.093564886073 6756.806499707274 12526.10743193013 12258.61427358543 0.6892193810566503 0.5210032183062656 0.8407730693723072 0.6895712184567477 0.6319377013980912 0.6137599205455959 0.46514992948043143 0.5511884417692039 1.0218208316515096 1.0 13.581508284058014 -8.267262009783437 24.84186059360724 1.0109105014536952 0.6256667876368669 0.7101751958088647 0.09852906092341661 265.300822431062 1131868.3969092818 0.09215290449548307 0.026354922068468515 5.404281843486106e-09 8.267262009783437 -0.3852437138168283 S(ph)QSSSNCSNPISVPLR ddPTM_PC-9_AZD4547_30min_R2 2 SQSSSNCSNPISVPLR 16 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 S(0.971)QS(0.014)S(0.014)S(0.001)NCSNPISVPLR;S(0.999)QS(0.001)SSNCSNPISVPLR 126.07 2.9472e-05 8912900.0 21285.7 27470.0 37186.0 39501.0 34413.0 33850.0 30056.0 41318.0 36210.0 30817.0 True False 28054.109829935758 36349.140294871744 36692.889343099225 30394.654734366362 29635.348961618867 31733.35414889122 32730.925773812847 34933.25249318507 38123.98667581988 29738.106209964768 0.9433724404594154 1.2223085101058562 1.2338677212338431 1.0220776844283916 0.9965445934041534 1.0670939811983682 1.1006392116134562 1.1746966079998562 1.2819910725534074 1.0 14.860025155773487 -7.716434873866299 5.193358506502423 1.1715456650030571 1.087739264918848 0.07060004500610317 0.1072612043288585 0.4612586199203685 28.013082538560337 0.05505589095258058 0.02994905474045541 1.921167035410852e-08 7.716434873866299 -0.08380640008420914 S(ph)QSSSNCSNPISVPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSSSNCSNPISVPLR 16 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 S(0.843)QS(0.084)S(0.035)S(0.035)NCS(0.004)NPISVPLR 90.45299999999999 0.0035079 3061700.0 2284.0 5677.5 7191.4 6113.4 8864.0 4906.6 9902.0 7958.2 6717.9 6528.2 True False 2670.6360889437287 6241.1246787096625 7362.870249536373 5770.886017910216 7127.162830756414 4649.289258424354 8964.010875728161 7749.3056824098985 6816.136578481835 7711.710982797232 0.3463091517435242 0.8093047953472252 0.9547648071823452 0.7483275800640767 0.9241999404094904 0.6028868650284842 1.1623893706240387 1.0048750140787863 0.8838682613607818 1.0 12.912835268348934 -4.762932355106458 3.2770618792611805 0.902805305517021 0.25551803902215586 0.5804187042518552 0.14310263519826497 0.2575346420340738 4.165954854097044 0.036637923280835816 0.4387685010028988 1.7261067261977143e-05 4.762932355106458 -0.6472872664948651 S(ph)QSSSNCSNPISVPLR ddPTM_PC-9_Lapatinib_30min_R1 2 SQSSSNCSNPISVPLR 16 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 S(0.999)QS(0.001)SSNCSNPISVPLR;S(0.994)QS(0.006)SSNCSNPISVPLR 218.83 2.9188999999999998e-22 9149800.0 4026.9 11441.5 12816.8 11973.4 15526.2 16552.300000000003 16622.2 18743.3 17520.7 14759.9 True False 3969.475667556982 11415.007909713668 11763.052178278733 12853.9637780915 14612.979441683667 15844.396714295872 17482.81618295076 19614.182143780716 15547.334264849698 17311.129048669492 0.22930195115506172 0.6594028545232876 0.6795080866884776 0.7425260213792605 0.8441378607137585 0.9152722892741446 1.0099177317550216 1.13303887277579 0.8981120885379018 1.0 14.079412201295995 -4.994266727550473 0.5190008804345321 1.0264585523977714 1.2498952117193009e-14 0.8653623600391461 0.08851236047225026 1.2590133051335446 0.30482765248890753 0.056062925522058535 0.7660093505644635 1.01328887018086e-05 4.994266727550473 -1.026458552397759 down S(ph)QSSSNCSNPISVPLRR ddPTM_PC-9_AZD4547_30min_R2 1 SQSSSNCSNPISVPLRR 17 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 S(0.999)QSSSNCSNPISVPLRR 84.436 0.0015611 9662500.0 7290.5 8907.2 16666.0 17233.0 9056.7 17640.0 23329.0 17254.0 9086.6 15313.0 True False 9608.727348179604 11786.278210210483 16444.997950629036 13260.198097195906 7799.33353502147 16536.96801141628 25405.23580573862 14587.790757476534 9566.899125338434 14776.896530914453 0.6502534093053555 0.7976152628227885 1.1128857751845782 0.8973601506550788 0.5278059245190381 1.119109684284492 1.7192538198118141 0.9872026055645517 0.6474227592596127 1.0 13.851055683566821 -6.909675962721106 14.220002376475383 1.1347812018816599 0.820382663050645 0.20325247476624642 0.2873359671052417 1.4859059316671301 228.32048238678277 0.10730408755877395 0.09463617566127333 1.2311870456709435e-07 6.909675962721106 -0.3143985388310149 S(ph)QSSSNCSNPISVPLRR ddPTM_PC-9_Lapatinib_30min_R1 1 SQSSSNCSNPISVPLRR 17 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 S(0.917)QS(0.016)S(0.012)S(0.043)NCS(0.013)NPISVPLRR 61.942 0.013975999999999999 8586800.0 14227.0 8637.3 28857.0 11887.0 20928.0 16616.0 15578.0 12471.0 14920.0 14498.0 True False 14024.12037108773 8617.300862524133 26484.488851241287 12761.209633869561 19697.056186031085 15905.37241378782 16384.552616260597 13050.448187623808 13239.552485434806 17003.959982629316 0.8247561383003905 0.5067820008590518 1.5575482933561926 0.7504845722352905 1.1583805305442347 0.9353922515717646 0.9635727579339468 0.767494642480676 0.7786158341327488 1.0 14.053583148383343 -7.743262541281455 23.578731775064846 0.8297914852314316 0.9615130292631231 0.03215008964611854 0.26461064832132386 423.68413083016384 549598.941113035 0.12281946913632075 0.07068561174642057 1.8060819766767044e-08 7.743262541281455 0.13172154403169145 S(ph)QSYIPTSGCR ddPTM_PC-9_AZD4547_30min_R2 3 SQSYIPTSGCR 11 0 A0A087WZ32;A0A087X038;A8K727;Q9HB19;E5RHB5 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 S(0.996)QS(0.002)YIPT(0.002)SGCR;S(0.952)QS(0.048)YIPTSGCR;S(0.822)QS(0.17)YIPT(0.008)S(0.001)GCR 135.04 6.7623e-05 315371000.0 111023.0 113009.0 179508.0 211699.0 182135.0 161174.0 162261.0 213957.0 156734.0 149236.0 True False 146326.00457814184 149536.949238557 177127.60663155658 162895.06626694577 156848.699128947 151095.76430113445 176701.91465879141 180894.86189274423 165018.6392611972 144011.29306390323 1.0160731249959092 1.0383696032241154 1.2299563656647288 1.131127030396589 1.0891416623788477 1.0491938589433232 1.2270004032279755 1.2561158090044673 1.1458729086473256 1.0 17.13582242366317 -7.261495851859181 24.99999999832694 1.1785902635244399 1.0977354367252963 0.10068902430921112 0.08516995337585227 9.65660539600607 4272743.732206978 0.03447789426081236 0.024952526563064254 5.4765133179970063e-08 7.261495851859181 -0.08085482679914358 S(ph)QSYIPTSGCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQSYIPTSGCR 11 0 A0A087WZ32;A0A087X038;A8K727;Q9HB19;E5RHB5 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 S(0.754)QS(0.145)Y(0.004)IPT(0.097)S(0.001)GCR;S(0.736)QS(0.25)YIPT(0.011)S(0.003)GCR 148.89 7.8018e-05 136823000.0 146277.0 133712.0 138092.0 160022.0 144337.0 128807.0 158482.0 137051.0 118190.0 91015.0 True False 171038.80699755764 146986.04368817754 141384.63699682654 151056.48613832376 116055.20098182421 122052.13416823585 143469.43764968222 133453.55646753794 119918.30515648736 107515.29902565652 1.5908322680360347 1.3671174709108334 1.3150187766588244 1.4049766638539223 1.079429644279088 1.1352071312112555 1.3344095114821373 1.2412517816249735 1.1153603835289625 1.0 16.71418243897714 -1.5228787452803376 0.2897146086073726 1.1168950398798554 4.609171876545707 0.6582311413851936 0.09913068290291306 36.88046169684984 0.5232583354736311 0.110759852358967 65.95800280780291 0.029999999999999995 1.5228787452803376 3.4922768366658516 S(ph)QSYIPTSGCR ddPTM_PC-9_Lapatinib_30min_R1 2 SQSYIPTSGCR 11 0 A0A087WZ32;A0A087X038;A8K727;Q9HB19;E5RHB5 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 S(0.992)QS(0.008)YIPTSGCR;S(0.806)QS(0.182)YIPT(0.013)SGCR 159.79 7.8018e-05 103354000.0 108608.0 130306.0 146867.0 113531.0 127090.0 134995.0 119914.0 121035.0 134692.0 93647.0 True False 107059.23000373192 130004.28446297649 134792.16218301447 121880.4484683135 119614.81606855363 129221.57853871486 126122.56017629174 126658.72795999135 119521.56859036084 109833.75917321637 0.9747388308442689 1.1836459522244853 1.227237993105897 1.1096811161320497 1.0890532835165168 1.1765196740186448 1.148304138233006 1.1531857683232047 1.0882042961114173 1.0 16.74496203247763 -8.595381678944582 3.3326052487449918 1.0001026860419087 1.137116409858656 0.28075682492539655 0.06457648855458077 0.4086136452359611 11.567107018253035 0.06154314765034007 0.01627381988595999 2.5387405571420818e-09 8.595381678944582 0.13701372381674726 S(ph)QTLPIIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQTLPIIR 8 0 Q96BY6;A0A2R8YD85;Q96BY6-3;H7C0I3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 S(0.789)QT(0.211)LPIIR 112.85 0.0037234 29674000.0 37987.0 37500.0 34077.0 37590.0 49071.0 35924.0 38819.0 30130.0 29391.0 24766.0 True False 44417.44882255049 41222.75217113384 34889.52491774218 35483.95416842431 39455.88980912091 34040.08219941235 35141.783294777975 29339.119425373847 29820.78777269081 29255.879752451885 1.5182400665571487 1.4090416189818744 1.1925645447328634 1.2128828279536 1.3486482082568096 1.163529604559559 1.2011870294836307 1.0028452288437844 1.0193092132254742 1.0 14.836438981586861 -1.522878745280569 0.18275420754651495 0.9430594656361412 3.3409789955764153 0.7927008936330714 0.07614256914478809 26.93278532917119 0.3066600786560329 0.18285083395103888 18.00881711509524 0.029999999999984015 1.522878745280569 2.3979195299402742 S(ph)QTLPIIR ddPTM_PC-9_Lapatinib_30min_R1 2 SQTLPIIR 8 0 Q96BY6;A0A2R8YD85;Q96BY6-3;H7C0I3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 S(0.626)QT(0.374)LPIIR;S(0.92)QT(0.08)LPIIR 111.27 0.0037486999999999993 44146000.0 210849.0 192919.0 182574.0 171835.0 142359.0 158554.0 117890.0 113940.0 151481.0 100793.0 True False 207842.25459502896 192472.30790840794 167563.47047602065 184472.319124756 133985.72350856266 151773.01502742624 123993.76735979975 119234.06835842038 134419.6146143533 118214.93575176985 1.7581725462462747 1.6281555852854772 1.4174475451044009 1.5604823362769893 1.1334077429091416 1.283873429886409 1.0488841073361863 1.008621013919853 1.1370781006607353 1.0 16.851052797378138 -5.744510729584728 0.4909730886097431 1.0049153548687089 1.9091848432672847 0.8777688115568507 0.09195051850666185 0.6140579236265007 0.22028348244396045 0.06799454275097394 0.2924060758464907 1.8008986412833423e-06 5.744510729584728 0.9042694883985758 S(ph)QVIAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQVIAEK 7 0 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 S(1)QVIAEK;S(1)QVIAEK 77.062 0.030343000000000002 22655000.0 104765.0 159852.0 148941.0 151384.0 174872.0 138334.0 175062.0 122043.0 124070.0 108448.0 True False 122499.64529693041 175721.05013493577 152492.31830188812 142902.44527355 140607.0869291558 131079.52151691093 158478.86002087724 118839.50056524742 125884.28903262048 128108.7639261045 0.9562159647999606 1.3716551838428082 1.1903347876328625 1.115477512186276 1.0975602497441983 1.0231893392751805 1.2370649373550335 0.9276453610449028 0.9826360443633104 1.0 16.967009648322794 -7.325650634084986 0.6421525538907967 0.9687680817885163 1.1784107523146394 0.22703100843682344 0.11798101500646588 1.0537007752287475 0.8699600938889281 0.10412112729077495 0.06997323615874955 4.7244294268218155e-08 7.325650634084986 0.20964267052612318 S(ph)QVIAEK ddPTM_PC-9_Lapatinib_30min_R1 1 SQVIAEK 7 0 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 S(1)QVIAEK 74.962 0.033416 19944000.0 62873.0 94703.0 72747.0 67693.0 78164.0 81867.0 78607.0 66292.0 78291.0 59269.0 True False 61976.41949050393 94483.72102203497 66766.02247154064 72671.36903722816 73566.54719633667 78365.73925129794 82676.88583299496 69372.16833084427 69473.04313922087 69513.56767902168 0.8915729915730917 1.3592126569925567 0.9604746914995385 1.045427122555234 1.0583048698641047 1.1273445151477635 1.1893632940083696 0.9979658741034511 0.9994170269034682 1.0 16.085006970520627 -7.8539825252278685 24.999678621633297 0.9990133924296214 1.0940754138271531 0.10810390548194726 0.11957810071383042 39.53432894377063 10664.424344985651 0.0622043811330304 0.02988201967823917 1.3996436391103942e-08 7.8539825252278685 0.09506202139753173 S(ph)QVIEK ddPTM_PC-9_Lapatinib_30min_R1 1 SQVIEK 6 0 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 S(1)QVIEK 85.29 0.041572000000000005 13553000.0 26392.0 34600.0 33716.0 34183.0 40462.0 26498.0 31420.0 31462.0 36288.0 25643.0 True False 26015.645240299964 34519.885825817655 30944.000627523706 36696.931851145215 38082.104711352724 25364.742309854966 33046.773860759284 32923.83937767784 32200.863310419423 30075.358382850292 0.8650153028645112 1.1477797001249281 1.0288821909822605 1.2201660703092638 1.2662228069431112 0.8433729030580253 1.0987990048226113 1.0947114564211418 1.0706726383942657 1.0 14.876294308441418 -9.92355304552842 15.224493450313823 0.9999997342364516 1.0766705986594618 0.024747923835036434 0.1280383222770652 0.0 0.0 0.12279446410062315 0.029782032101646195 1.1924686066471363e-10 9.92355304552842 0.07667086442301019 S(ph)QVIEKFEALDIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQVIEKFEALDIEK 14 1 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 S(1)QVIEKFEALDIEK 96.756 0.0013545 1420200.0 6963.1 4075.2 5381.5 6052.1 11641.0 8556.1 7826.5 9006.4 7030.7 5443.5 True False 8141.8153025061565 4479.758923941457 5509.815369452401 5713.0204581729395 9360.029615617708 8107.40305384678 7085.1172610469 8769.991543069602 7133.51068672237 6430.363459277712 1.2661516497577079 0.6966571877796539 0.8568435368148364 0.8884444082130705 1.4555988436568204 1.2608001250923755 1.1018222073939712 1.3638407220071334 1.1093479757244764 1.0 12.650684569039289 -6.234666987932746 24.73122575696494 1.2300346377232356 0.9055564404071307 0.37287337528633724 0.1816543493474875 620.1796933046185 572896.1003993968 0.051571976607242394 0.06656025941633108 5.825497390668444e-07 6.234666987932746 -0.32447819731610494 S(ph)QVMTHLR ddPTM_PC-9_Lapatinib_30min_R1 1 SQVMTHLR 8 0 H7C0V9;A0A0A0MRG2;E9PG40;P05067-10;P05067-3;P05067-4;P05067-5;P05067-6;P05067-7;P05067-11;P05067-8;P05067-9;P05067 H7C0V9 APP Amyloid beta A4 protein;N-APP;Soluble APP-alpha;Soluble APP-beta;C99;Beta-amyloid protein 42;Beta-amyloid protein 40;C83;P3(42);P3(40);C80;Gamma-secretase C-terminal fragment 59;Gamma-secretase C-terminal fragment 57;Gamma-secretase C-terminal fragment 50;C31 1 S(0.999)QVMT(0.001)HLR 80.165 0.019684 36280000.0 3850.2 2611.3 2800.1 3489.0 3439.2 3293.0 1280.3 2727.9 2709.9 3091.7 True False 3795.2954419597922 2605.2536952877945 2569.886586698574 3745.5926989628056 3236.9130177273537 3152.166066357928 1346.5876694439874 2854.6481926885567 2404.6825254879195 3626.096225568702 1.046661535123645 0.718473403137336 0.7087199089140342 1.0329545786875423 0.8926715719519246 0.8693001702853473 0.3713601586049455 0.7872510863224116 0.6631601523786863 1.0 11.824201494992026 -7.0799516682439165 24.999999999626578 0.6780872254261473 0.8710448954771837 0.17721894470614907 0.17804495150064964 165.61100270604132 51782.99259122863 0.06598678566438024 0.05111315739993338 8.318563415643835e-08 7.0799516682439165 0.19295767005103637 S(ph)QVNGEAGSYEMTNQHVK ddPTM_PC-9_AZD4547_30min_R2 2 SQVNGEAGSYEMTNQHVK 18 0 Q05D32;H0YMH7;Q05D32-2 Q05D32 CTDSPL2 CTD small phosphatase-like protein 2 1 S(1)QVNGEAGSYEMTNQHVK;S(0.999)QVNGEAGSYEMTNQHVK 156.7 9.2619e-06 42289000.0 44091.0 46893.0 63234.0 80154.0 70257.0 66238.0 56179.0 78842.0 53473.0 62577.0 True False 58111.020850227986 62050.245207405256 62395.47584363839 61675.733666955326 60503.02827409576 62096.127388899695 61178.82216685627 66658.78050892334 56299.47361270689 60386.198276956406 0.9623228901363603 1.0275567427314571 1.0332737881173872 1.0213548033622613 1.001934713568215 1.0283165551191158 1.013125911425398 1.1038744350687262 0.9323235311899238 1.0 15.881931227896166 -6.776891595018647 24.507606505654802 1.0218700989762644 1.0123063374882657 0.0 0.043243054347235174 1462.9804965958892 2320303.704530601 0.01458426935304863 0.012903667207850758 1.6715077901337063e-07 6.776891595018647 -0.009563761487998645 S(ph)QVNGEAGSYEMTNQHVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SQVNGEAGSYEMTNQHVK 18 0 Q05D32;H0YMH7;Q05D32-2 Q05D32 CTDSPL2 CTD small phosphatase-like protein 2 1 S(0.989)QVNGEAGS(0.008)Y(0.001)EMT(0.002)NQHVK;S(1)QVNGEAGSYEMTNQHVK;S(0.998)QVNGEAGS(0.001)YEMTNQHVK 132.24 2.7923e-05 35459000.0 67293.0 94129.0 83737.0 87611.0 116403.0 101944.0 110976.0 96607.0 86380.0 76151.0 True False 78684.37580266644 103473.5050431109 85733.60765434112 82702.43970869428 93594.66775592708 96597.87717784461 100463.54988333749 94071.16861357765 87643.1440850952 89956.57348901556 0.8746928962592652 1.1502606316562944 0.9530555058859584 0.9193596032066843 1.0404427839545907 1.073827886403877 1.1168005403807975 1.0457397938246784 0.9742828198741603 1.0 16.456941088413593 -6.491295912803174 23.563023323615486 1.0504869092760853 0.9847015017082975 0.14884912152972551 0.0762257022100957 665.7132833096485 496668.7864945598 0.02364863195089154 0.02677925887943989 3.226295089978149e-07 6.491295912803174 -0.06578540756778783 S(ph)QVNGEAGSYEMTNQHVK ddPTM_PC-9_Lapatinib_30min_R1 3 SQVNGEAGSYEMTNQHVK 18 0 Q05D32;H0YMH7;Q05D32-2 Q05D32 CTDSPL2 CTD small phosphatase-like protein 2 1 S(1)QVNGEAGSYEMTNQHVK;S(1)QVNGEAGSYEMTNQHVK;S(1)QVNGEAGSYEMTNQHVK 140.93 3.0525e-05 35998000.0 66894.0 70572.0 82957.0 70611.0 96758.0 102214.0 95875.0 98635.0 119947.0 84728.0 True False 65940.0792931427 70408.59486993075 76136.59568328044 75803.96849139068 91066.88467354719 97842.54549247173 100838.93838002226 103217.94218477065 106437.3057620944 99373.12190703646 0.6635605083920945 0.7085275527098562 0.7661689018334978 0.7628216467054872 0.9164136431050264 0.9845976820976141 1.0147506332180756 1.0386907465917294 1.0710874703289133 1.0 16.600568069012333 -6.332329455868324 0.9843841555411764 1.0434105847565998 0.6847876200922022 0.9700003096869168 0.024971181062412813 0.08230561483241325 0.16991997788019733 0.011856728784020096 0.017151773647417594 4.6523303376523067e-07 6.332329455868324 -0.3586229646643976 S(ph)RASPVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRASPVSR 8 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.996)RAS(0.004)PVSR;S(0.974)RAS(0.026)PVSR 72.096 0.01586 222625700.0 4266.1 5385.19 5822.5 4054.5 8120.6 8986.37 4730.41 7176.9 7030.33 5580.7 True False 4988.2664706842515 5919.796073719153 5961.330481954214 3827.3395098663577 6529.426724214862 8515.108937599736 4282.311319597377 6988.513979554112 7133.135276172344 6592.436733203111 0.7566650500505554 0.897967824841432 0.9042681368377339 0.5805652241742095 0.9904420760428544 1.2916481844585628 0.6495794336605947 1.0600805532734414 1.082018010160944 1.0 12.686596105453159 -6.4858889004340385 24.85680905519908 1.0134293947953357 0.7994775627138967 0.3011558856702907 0.16949645597897334 738.6252906752718 496349.0414172394 0.052595049415061296 0.059619079728770646 3.266713893191526e-07 6.4858889004340385 -0.21395183208143898 S(ph)RDDLYDQDDSRDFPR ddPTM_PC-9_AZD4547_30min_R2 1 SRDDLYDQDDSRDFPR 16 2 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 1 S(0.868)RDDLY(0.131)DQDDSRDFPR 84.208 0.014136000000000001 12530000.0 8457.3 17820.0 14883.0 14958.0 8521.5 9224.2 12556.0 13665.0 9955.1 11830.0 True False 11146.545477231934 23579.966510906983 14685.641695620552 11509.664198796287 7338.436816797001 8647.409315811 13673.459675804972 11553.38824046115 10481.306262260547 11415.835300771758 0.9764108524304289 2.065548940541642 1.2864272572877555 1.0082191881323117 0.64282959796213 0.7574924732162526 1.1977625215809298 1.0120493101087482 0.9181374806232503 1.0 13.478748805488916 -5.648458384604756 3.571418449370921 0.923827598817855 1.5501540917980148 0.41413423226462465 0.28388625474709667 0.1972247179460688 4.816942405504428 0.07720960559596188 0.1420586282955032 2.2466820494663285e-06 5.648458384604756 0.6263264929801597 S(ph)RDDLYDQDDSRDFPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRDDLYDQDDSRDFPR 16 2 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 1 S(0.999)RDDLYDQDDS(0.001)RDFPR 137.69 6.3077e-07 0.0 11855.0 13703.0 11770.0 11410.0 18850.0 14957.0 11124.0 16012.0 8074.5 8096.2 True False 13861.81735307701 15063.343280027922 12050.641437973569 10770.73469171911 15156.477815857215 14172.628589706335 10070.254189214305 15591.701966116367 8192.57428704678 9563.976970516058 1.4493779518510328 1.57500831782274 1.2600031843576611 1.1261773972190918 1.5847463730393523 1.4818760682295538 1.0529358466942156 1.6302529809704323 0.8566074878999548 1.0 13.223394940792527 -8.275300517588347 24.983574188525562 0.9283036452000594 1.3853960533103946 0.4964568424292184 0.1878240142751354 750.492865677307 1352688.344978209 0.1752108303421143 0.04617393457196699 5.3051721661476405e-09 8.275300517588347 0.45709240811033525 S(ph)RDDLYDQDDSRDFPR ddPTM_PC-9_Lapatinib_30min_R1 2 SRDDLYDQDDSRDFPR 16 2 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 1 S(0.944)RDDLY(0.056)DQDDSRDFPR;S(0.928)RDDLY(0.058)DQDDS(0.014)RDFPR 106.75 0.0027681 22363100.0 25532.0 30841.0 18018.8 18717.4 21285.8 16032.4 15491.0 13407.5 19009.5 11880.3 True False 25167.908998004634 30769.589559365377 16537.363818579426 20093.940035416006 20033.811093492943 15346.731625349785 16293.048181954875 14030.461396485147 16868.44993109067 13933.794025495314 1.8062495363397604 2.208270733948329 1.1868528979487023 1.442101124693618 1.437785793075177 1.1014036519607764 1.169318862625838 1.0069376202068838 1.210614273486868 1.0 13.766300521659085 -5.150633681388131 0.5990777133044667 1.083812279941756 2.3983977521087407 0.6829751234382712 0.20620078873729425 1.3958691093574422 0.514596112511824 0.10939714376666411 1.1937249481132919 7.069135701630354e-06 5.150633681388131 1.3145854721669847 S(ph)RDRHDDYYR ddPTM_PC-9_AZD4547_30min_R2 1 SRDRHDDYYR 10 2 F8WJN3;Q16630-3;Q16630;Q16630-2 F8WJN3 CPSF6 Cleavage and polyadenylation specificity factor subunit 6 1 S(1)RDRHDDYYR 62.303000000000004 0.019212 9518700.0 988.5 1011.4 1472.7 1734.2 1174.1 1823.1 621.75 1211.3 0.0 1163.5 True False 1302.822437922713 1338.3152709950239 1453.1710357549146 1334.4069831229112 1011.09648144122 1709.101268798924 677.0845455106514 1024.12141790491 0.0 1122.766219141838 1.1603683970101069 1.1919803501194897 1.2942774826852328 1.1884994047494912 0.9005405258932974 1.5222236291587383 0.6030503358287411 0.9121412814572164 0.0 1.0 10.132841847667114 -7.2826396519489895 24.250452289750186 0.6214762100559137 1.1976803170402641 0.49688354304526927 0.286146659479238 464.69494660216776 531549.8826236487 0.1128423298706556 0.07617611610955638 5.216273425207146e-08 7.2826396519489895 0.5762041069843504 S(ph)RDRHDDYYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SRDRHDDYYR 10 2 F8WJN3;Q16630-3;Q16630;Q16630-2 F8WJN3 CPSF6 Cleavage and polyadenylation specificity factor subunit 6 1 S(1)RDRHDDYYR;S(1)RDRHDDYYR;S(1)RDRHDDYYR;S(1)RDRHDDYYR 61.78 0.01994 20171700.0 6236.6 5903.5 9506.699999999999 12699.199999999999 13068.4 15672.8 12000.4 16687.9 13620.140000000001 9502.5 True False 7292.333201535221 6489.560465127696 9733.375782360517 11987.7049953619 10507.740832294345 14850.890777612456 10863.635236627779 16249.860307291605 13819.308780726647 11225.228028251382 0.6496378677726682 0.578122818422479 0.8670982681032219 1.0679252987281447 0.9360826172839177 1.3229923472588792 0.967787488083667 1.4476196177391096 1.2310938135017433 1.0 13.454457131588125 -5.606909014262483 0.8220701874645945 1.2087728226096883 0.506678192742397 0.6636815413913726 0.15186610493484656 0.5469874268442204 0.5986175147398839 0.06425918368071583 0.2842609073939382 2.4722420314111014e-06 5.606909014262483 -0.7020946298672913 S(ph)RDRHDDYYR ddPTM_PC-9_Lapatinib_30min_R1 2 SRDRHDDYYR 10 2 F8WJN3;Q16630-3;Q16630;Q16630-2 F8WJN3 CPSF6 Cleavage and polyadenylation specificity factor subunit 6 1 S(1)RDRHDDYYR;S(1)RDRHDDYYR 63.076 0.018137 11242600.0 3394.4 2690.31 3464.1 2642.99 1502.68 2126.8599999999997 1273.05 1174.9 6186.9 3020.3 True False 3345.9952335432768 2684.0807524871534 3179.295069812695 2837.3643013561773 1414.295316782548 2035.899155752814 1338.96229991851 1229.4901431833237 5490.06617105473 3542.3548307032224 0.9445680609243302 0.7577108677038754 0.8975089232327261 0.8009825206564382 0.39925286550184036 0.5747304414867583 0.37798649878693874 0.3470827181192482 1.5498351897076474 1.0 11.790493015909567 -11.136846284720768 13.490829224320677 1.0000018033195555 0.7089479146206231 0.04383091224377755 0.3410892762563172 1.8397164202726157e-05 5.263507215030783e-07 0.32841550308046125 0.0796519658059145 7.297157419739651e-12 11.136846284720768 -0.29105388869893234 S(ph)RDSGDENEPIQER ddPTM_PC-9_AZD4547_30min_R2 1 SRDSGDENEPIQER 14 1 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;Q8WX93-4;Q8WX93-7 Q8WX93-3 PALLD Palladin 1 S(0.775)RDS(0.225)GDENEPIQER 87.863 0.0028037 13855000.0 22705.0 19763.0 32077.0 39251.0 33367.0 31128.0 28367.0 36484.0 32889.0 27181.0 True False 29924.717706661824 26151.003263471084 31651.638021260547 30202.288371904884 28734.5680063446 29181.561239193074 30891.6080458394 30846.23611891581 34627.44539577573 26229.401463252492 1.1408845050691105 0.9970110564706844 1.2067236099765613 1.1514669297436475 1.095509863105411 1.112551549454019 1.1777473492530388 1.1760175375001036 1.320176727794911 1.0 14.678897266227846 -7.290750315436783 5.509718828424169 1.1838287324847125 1.1164152689705973 0.06473665391022687 0.0878407027973435 0.4348091489938413 40.124410273834044 0.03560353682599063 0.024431212998466564 5.1197609621731875e-08 7.290750315436783 -0.06741346351411526 S(ph)RDSGDENEPIQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRDSGDENEPIQER 14 1 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;Q8WX93-4;Q8WX93-7 Q8WX93-3 PALLD Palladin 1 S(0.938)RDS(0.062)GDENEPIQER 114.21 0.00085341 6971000.0 11631.0 15210.0 14351.0 12375.0 17633.0 13276.0 11430.0 12237.0 11553.0 12782.0 True False 13599.898577278678 16719.948280611883 14693.182266470576 11681.668870291323 14177.94022954962 12579.78318893771 10347.26765396616 11915.791716173242 11721.94076887131 15099.275417743667 0.9006987554712049 1.1073344791739945 0.9731051232567175 0.7736575793937636 0.9389814966146418 0.8331382030527626 0.6852823971809097 0.7891631476680393 0.7763247205290701 1.0 13.882191698880623 -5.664756679613107 5.3200573492770165 0.8184800803093958 1.0116842846446619 0.3831141082668654 0.09588138018366384 0.18944410472113357 8.386869808897854 0.025965061091413603 0.04554544765648491 2.1639305606575975e-06 5.664756679613107 0.19320420433526608 S(ph)RECDITK ddPTM_PC-9_AZD4547_30min_R2 1 SRECDITK 8 1 Q13427;E9PG73 Q13427 PPIG Peptidyl-prolyl cis-trans isomerase G 1 S(1)RECDITK 58.172 0.037135 22340000.0 43847.0 43435.0 54992.0 51531.0 50666.0 53824.0 50427.0 56062.0 50277.0 48250.0 True False 57789.43392574329 57474.51433228089 54262.77014886554 39651.324096013595 43631.90045882029 50458.376771341806 54914.90530995674 47398.90607659958 52934.53957747019 46560.782186156976 1.2411611491983205 1.23439752585103 1.1654179247228893 0.8516034790283734 0.9370955213847874 1.0837098176229443 1.1794240287974271 1.0180006402618338 1.1368911150553695 1.0 15.506827674191932 -5.5358325322578965 24.985692469719876 1.0329009464213548 1.2283114764166176 0.48694459567471227 0.08855428102116777 197.55787183877428 381054.7060007712 0.02623509803265821 0.04547391171476462 2.911839732418812e-06 5.5358325322578965 0.19541052999526287 S(ph)RECDITK ddPTM_PC-9_Lapatinib_30min_R1 2 SRECDITK 8 1 Q13427;E9PG73 Q13427 PPIG Peptidyl-prolyl cis-trans isomerase G 1 S(1)RECDITK;S(1)RECDITK 62.408 0.029285000000000002 47991000.0 174160.0 192559.0 160006.0 132885.0 157141.0 161235.0 126820.0 144222.0 162550.0 118545.0 True False 171676.44646296732 192113.14146628938 146850.92432102165 142657.80619136535 147898.2753310929 154339.3549071426 133386.11906497413 150923.0806282964 144241.90727261588 139035.34529871642 1.2347683683895037 1.3817575743314459 1.0562128932431787 1.026054244586987 1.0637458770885528 1.1100727989386125 0.9593684165590773 1.0855015341893046 1.0374477580698145 1.0 17.085092163177116 -5.2732360018733315 24.56414485321022 1.0449983212334724 1.3082629640233165 0.8077190579518367 0.05189274555066614 191.29608411351856 398336.9147630728 0.012728386025157136 0.026853667494869872 5.330451523602394e-06 5.2732360018733315 0.2632646427898442 S(ph)REDLSALTR ddPTM_PC-9_AZD4547_30min_R2 1 SREDLSALTR 10 1 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 S(0.995)REDLS(0.004)ALT(0.001)R 59.75 0.033596 7702700.0 7193.9 2082.5 8024.4 10559.0 11736.0 8605.5 9391.3 9395.8 7796.1 7657.8 True False 9481.410557584426 2755.627399492918 7917.991212950179 8124.785684923788 10106.658978105921 8067.396724616939 10227.107506641225 7943.89500400475 8208.185929946409 7389.702752852915 1.2830570964338144 0.3729009801414628 1.0714898119404477 1.0994739513422351 1.3676678637992685 1.0917078797929172 1.3839673730709783 1.0749952020651818 1.1107599594283417 1.0 12.85130061850445 -5.505193067514811 24.230998561305938 1.1721161689709474 0.8015330860977573 0.235824278897382 0.235218128531142 557.5468851784082 763887.991264829 0.05735598991403547 0.11535039611830752 3.1246899636998153e-06 5.505193067514811 -0.3705830828731901 S(ph)REDLSALTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SREDLSALTR 10 1 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 S(0.999)REDLS(0.001)ALTR 55.105 0.043131 2286600.0 4406.2 4401.8 3512.3 6048.3 6330.8 5657.8 4124.4 3950.7 5088.9 3958.8 True False 5152.082633583124 4838.781613517249 3596.046552471925 5709.433359853167 5090.325186028054 5361.095008012334 3733.7069739298336 3846.99831111266 5163.315535247059 4676.49910215644 1.1016964872734354 1.0347017090810466 0.7689612408593656 1.220877676897322 1.0884905727194065 1.1463906847624992 0.7983978810576776 0.8226235538757447 1.1040984767571402 1.0 12.191213195237522 -7.254784095547471 24.99752069907159 0.9164986068654062 1.0543811933529648 0.1723320738570545 0.13651643193963112 945.190150419866 3550180.7284510136 0.0544034747509765 0.04116977837733476 5.561806873152075e-08 7.254784095547471 0.13788258648755858 S(ph)REDLSALTR ddPTM_PC-9_Lapatinib_30min_R1 2 SREDLSALTR 10 1 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 S(0.997)REDLS(0.002)ALTR;S(1)REDLSALTR 92.906 0.0033656999999999997 15078600.0 15948.6 12633.6 11435.3 16711.8 12494.400000000001 11491.7 10413.9 8171.799999999999 16086.099999999999 7083.6 True False 15721.17003938497 12604.347675406074 10495.133775534523 17940.841520930535 11759.503956935532 11000.226779461094 10953.080786395962 8551.491660622587 14274.314023857421 8307.9908216963 1.8922950658935696 1.5171354838873736 1.2632577479655496 2.159468144100264 1.4154449865574736 1.3240537953814329 1.3183790186421507 1.0293092330206222 1.7181427291156945 1.0 13.020283907019353 -6.509246122317466 24.079725909152213 1.2920466404807143 1.6782359861889498 0.3346836266089406 0.28516028893221756 506.1073101180661 893955.0992102224 0.08806879263177761 0.09569889413674203 3.0956644345527026e-07 6.509246122317466 0.3861893457082355 S(ph)REDLSAQPVQTK ddPTM_PC-9_AZD4547_30min_R2 5 SREDLSAQPVQTK 13 1 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 S(1)REDLSAQPVQTK;S(1)REDLSAQPVQTK;S(1)REDLSAQPVQTK;S(1)REDLSAQPVQTK;S(0.979)REDLS(0.021)AQPVQTK 162.64 2.7536999999999997e-05 434725700.0 252548.0 276666.0 377460.0 457745.0 423936.0 391483.0 326585.0 404456.0 376036.0 412746.0 True False 332853.0106752715 366092.87400149263 372454.6337720169 352218.96233975206 365079.8040680228 367003.5061232016 355650.4323210222 341956.6186742738 395912.4952672909 398295.8881701044 0.8356928117046403 0.9191480125075795 0.9351204590215322 0.8843148342754826 0.9166045016063644 0.9214343331771015 0.8929302131513114 0.8585492063333346 0.9940160243336592 1.0 18.60348106047278 -8.278681670825257 23.715279196860177 0.9970080996562264 0.8986978513313353 0.6608602132439761 0.029020685192358654 292.76309070672727 402663.0714130479 0.0275026382580493 0.007188894494919735 5.264029678716321e-09 8.278681670825257 -0.0983102483248911 S(ph)REDLSAQPVQTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SREDLSAQPVQTK 13 1 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 S(0.991)REDLS(0.009)AQPVQTK;S(0.999)REDLS(0.001)AQPVQTK;S(0.999)REDLS(0.001)AQPVQTK;S(0.851)REDLS(0.149)AQPVQTK;S(0.9)REDLS(0.1)AQPVQTK 107.51 0.00047178 478990000.0 277994.0 310914.0 385918.0 443538.0 531611.0 441591.0 505480.0 441530.0 425635.0 372342.0 True False 325052.89356822305 341779.4871609577 395119.7487221659 418688.00382959726 427445.6407514952 418433.1905834734 457597.2750417155 429940.3053397046 431859.1066526904 439844.65714235004 0.7390174878559997 0.7770458992988181 0.898316581334056 0.9518997151171358 0.9718104649232057 0.9513203895712047 1.0403611084301976 0.9774821595719873 0.9818446118192241 1.0 18.746634561956434 -5.285357445630194 1.0934992602770677 0.9902291848695424 0.6951559035691012 0.9458561524016745 0.021524044938173455 0.17592834255599185 0.29779571404023913 0.007326898848144309 0.049422825254794765 5.1837321675815325e-06 5.285357445630194 -0.2950732813004412 S(ph)REDLSAQPVQTK ddPTM_PC-9_Lapatinib_30min_R1 5 SREDLSAQPVQTK 13 1 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 S(1)REDLSAQPVQTK;S(0.927)REDLS(0.073)AQPVQTK;S(0.896)REDLS(0.104)AQPVQTK;S(0.748)REDLS(0.252)AQPVQTK;S(1)REDLSAQPVQTK 127.18 0.00032435 596709700.0 629813.0 596958.0 690362.0 630065.0 736493.0 607878.0 617254.0 625350.0 753223.0 544601.0 True False 620831.7511264399 595575.7804279899 633603.1012343853 676402.0819352238 693173.929740949 581880.474972829 649212.3918729828 654406.0439524146 668387.0939501773 638734.5572147806 0.9719714459064085 0.9324308097952525 0.9919662151946637 1.0589721102373002 1.0852300410417008 0.9109895000986554 1.016404051635927 1.0245352103790502 1.0464238804687465 1.0 19.28485698064523 -5.498217909093957 6.651563971229615 1.019875221578972 0.9541421728914669 0.2734639609699544 0.04425374407237257 0.24430106951557667 41.24982394223441 0.012246594643820542 0.024378104907217875 3.1752804604760403e-06 5.498217909093957 -0.06573304868750507 S(ph)REDLTAVVSVSTK ddPTM_PC-9_AZD4547_30min_R2 1 SREDLTAVVSVSTK 14 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(1)REDLTAVVSVSTK 133.71 6.0527e-05 10257000.0 17603.0 21224.0 23642.0 29540.0 30597.0 37086.0 28101.0 34911.0 32253.0 31475.0 True False 23200.38783485435 28084.242942058918 23328.491632591613 22730.00938845047 26349.134692664185 34767.00655733472 30601.934561149683 29516.307124971783 33957.82773419547 30373.0698302444 0.7638473148918338 0.9246428859190798 0.7680649918817869 0.748360620625076 0.8675163505016102 1.144665545881536 1.0075351201635006 0.9717920279358959 1.1180242209294726 1.0 14.890505109755507 -6.607823844797451 5.882437517387357 1.043060385799453 0.807660470555493 0.7560883111733596 0.06714277381820705 0.10519068056719312 5.732224036827365 0.022293280884423915 0.022288590516463147 2.467039796114454e-07 6.607823844797451 -0.23539991524395998 S(ph)REDLTAVVSVSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SREDLTAVVSVSTK 14 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(0.924)REDLT(0.076)AVVSVSTK;S(0.849)REDLT(0.151)AVVSVSTK 137.27 3.2343e-05 29065000.0 121162.0 165723.0 180573.0 234080.0 281930.0 227570.0 256820.0 210845.0 222690.0 195233.0 True False 141672.33354141834 182174.88421484872 184878.54514691574 220965.256497599 226687.84035143885 215635.82858591093 232492.15038421602 205310.54215874334 225946.41996191075 230627.19743642266 0.6142915281293888 0.7899106707268085 0.8016337500605559 0.9581058043187332 0.9829189396186901 0.9349973939884326 1.0080864397977496 0.8902269309123508 0.9797041392925816 1.0 17.81520313180183 -4.8563001726298545 0.8711908813412187 0.9670269749896097 0.4592951848514668 0.8771435346865133 0.04189592857786868 0.6707897814755496 0.42703469042355985 0.014980556923161656 0.3200782742044602 1.3921942232394212e-05 4.8563001726298545 -0.5077317901381428 S(ph)REDLTAVVSVSTK ddPTM_PC-9_Lapatinib_30min_R1 3 SREDLTAVVSVSTK 14 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(0.684)REDLT(0.316)AVVSVSTK;S(0.846)REDLT(0.154)AVVSVSTK;S(0.994)REDLT(0.006)AVVSVSTK 133.9 7.4434e-05 33293200.0 225131.0 270797.0 284779.0 267432.0 314859.0 298640.0 291820.0 306290.0 322602.0 224190.0 True False 221920.59065603084 270169.9861842185 261365.56989873006 287099.84140699916 296339.6126566112 285867.86336384196 306929.0117137739 320521.3515666181 286267.1656103379 262940.942785602 0.8439940478839063 1.0274930306479921 0.9940086436513751 1.0918795618721728 1.1270196627318019 1.0871941825999087 1.167292580844053 1.218986089313471 1.0887127830972896 1.0 18.0043792773085 -3.678241540300506 0.5995167921926079 1.1313974386825376 2.78849211533952e-10 0.6325290840099353 0.06041089088453529 7.214243176672598 0.7183729660717982 0.027531519349342542 7.597095285802575 0.00020977728468890328 3.678241540300506 -1.1313974384036884 S(ph)REDSPELNPPPGIEDNR ddPTM_PC-9_AZD4547_30min_R2 1 SREDSPELNPPPGIEDNR 18 1 Q03164-2;Q03164;Q03164-3 Q03164-2 KMT2A Histone-lysine N-methyltransferase 2A;MLL cleavage product N320;MLL cleavage product C180 1 S(0.56)REDS(0.44)PELNPPPGIEDNR 69.922 0.025725 0.0 2126.0 2730.0 6551.7 10180.0 6872.3 6425.9 6111.0 10627.0 8361.0 6117.8 True False 2802.023776452899 3612.419111940294 6464.820177195267 7833.158279432152 5918.199769532836 6024.0874571745935 6654.867161424354 8984.841334166162 8802.9453906802 5903.617684113396 0.4746282578550319 0.6118992294608262 1.0950607785107875 1.32684037120343 1.0024700253640546 1.020406093264708 1.1272523929407838 1.521921271823601 1.4911103431322932 1.0 12.527383580739793 -5.257530418634841 2.838610611802786 1.215517950168008 0.49301384981450974 0.6867602541748097 0.17941180805418233 0.16469102607408223 2.616039307100172 0.053385000022137856 0.16429433584609682 5.526746964266844e-06 5.257530418634841 -0.7225041003534982 S(ph)REDSPELNPPPGIEDNR ddPTM_PC-9_Lapatinib_30min_R1 1 SREDSPELNPPPGIEDNR 18 1 Q03164-2;Q03164;Q03164-3 Q03164-2 KMT2A Histone-lysine N-methyltransferase 2A;MLL cleavage product N320;MLL cleavage product C180 1 S(0.884)REDS(0.116)PELNPPPGIEDNR 102.07 0.00022977 3467400.0 21506.0 20828.0 25302.0 17442.0 21405.0 22568.0 22199.0 20151.0 25607.0 16331.0 True False 21199.320496282617 20779.774045668502 23221.767228544468 18724.742864806336 20145.999983849168 21602.819248577493 23348.355599458788 21087.289024842237 22722.87000633572 19153.791590310346 1.106794986064643 1.0848908921083134 1.2123848752897604 0.9775998019253243 1.0518021922114245 1.127861245995079 1.2189939255301503 1.1009459367569825 1.1863379581633813 1.0 14.225342388779797 -6.959151391803689 12.390625248816454 1.1404676101937898 1.087727430090967 0.05229902365670103 0.07674204680354799 2.4088877066826098 726.1757788169538 0.026649944395921204 0.023494384882804788 1.098622800994079e-07 6.959151391803689 -0.05274018010282289 S(ph)REEDFR ddPTM_PC-9_Lapatinib_30min_R1 1 SREEDFR 7 1 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 1 S(1)REEDFR 55.461000000000006 0.044899 4135600.0 6167.3 6928.8 10386.0 5286.7 10270.0 9605.1 9287.5 10549.0 9984.8 6446.8 True False 6079.353171055696 6912.756789304199 9532.103171119381 5675.501553914204 9665.938791596858 9194.312263581694 9768.361305913486 11039.145051017846 8860.206679394729 7561.120790178969 0.8040280455447928 0.9142502786469274 1.2606733096369116 0.750616437881277 1.2783738098922857 1.215998595806597 1.2919197532992026 1.459987924720953 1.1718112863509764 1.0 12.884384386646229 -6.2865059465585595 24.503470596464027 1.2611090625382213 0.954544839746097 0.4368516079449921 0.1669034393732587 549.967383561077 537611.1464147927 0.05073103812302545 0.057548623988607224 5.170041788626535e-07 6.2865059465585595 -0.30656422279212425 S(ph)RERDHSRS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 SRERDHSRSR 10 3 F8WJN3;Q16630-3;Q16630;Q16630-2 F8WJN3 CPSF6 Cleavage and polyadenylation specificity factor subunit 6 2 S(1)RERDHS(0.051)RS(0.949)R 79.089 0.025669 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 S(ph)RESASPTIPNLDLLEAHTK ddPTM_PC-9_AZD4547_30min_R2 1 SRESASPTIPNLDLLEAHTK 20 1 O75151 O75151 PHF2 Lysine-specific demethylase PHF2 1 S(0.25)RES(0.25)AS(0.25)PT(0.25)IPNLDLLEAHTK 59.547 0.0075238 5944600.0 39652.0 44104.0 52417.0 83743.0 68220.0 57883.0 49448.0 57659.0 36775.0 58659.0 True False 52260.51118716382 58359.75549927281 51721.916331340646 64437.34516645263 58748.83056291634 54263.56685968304 53848.77620653104 48749.126422008754 38718.8514223495 56605.36626441003 0.9232430533714612 1.030993337745892 0.9137281453094351 1.1383610674906428 1.0378668038025571 0.9586293745757568 0.9513016125537876 0.861210334622624 0.6840137954675426 1.0 15.788651208508911 -7.640652168538094 2.251925767981223 0.824387747318145 1.005522762437211 0.34178470328640387 0.09356434503608735 0.3117264073325694 3.1600355998320357 0.05621915970541112 0.026752586875988534 2.2874300990857547e-08 7.640652168538094 0.18113501511906593 S(ph)RESASPTIPNLDLLEAHTK ddPTM_PC-9_Lapatinib_30min_R1 1 SRESASPTIPNLDLLEAHTK 20 1 O75151 O75151 PHF2 Lysine-specific demethylase PHF2 1 S(0.535)RES(0.155)AS(0.155)PT(0.155)IPNLDLLEAHTK 76.21 0.00092392 6333200.0 26431.0 17245.0 22538.0 16364.0 20295.0 15850.0 16202.0 19853.0 24725.0 14957.0 True False 26054.089093148224 17205.070262029636 20685.012639195913 17567.46314870375 19101.2880015052 15172.132448154623 17040.860283005157 20775.442856939753 21940.210134207467 17542.29752105026 1.4852153238128618 0.9807763345356582 1.1791507135467567 1.0014345685120944 1.0888703705192662 0.8648885603466989 0.9714155322332555 1.184305694964403 1.2507033419014721 1.0 14.098550089997856 -4.7550930767564505 24.99921602981674 1.057959392115219 1.4852160335475264 0.5659001604655953 0.1122649767752364 167.75034193775824 660736.4308663483 0.02925248405679563 0.267901929910995 1.757546901145929e-05 4.7550930767564505 0.42725664143230735 S(ph)RESLNVDVVK ddPTM_PC-9_AZD4547_30min_R2 4 SRESLNVDVVK 11 1 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;G3V3H3;H0YJT3;F8W6L3;E7EVH7;G5E9S8;H0YJU9;H0YJL0;G3V2E7;Q07866-8;Q07866-2;Q07866-3;Q07866-5;Q07866-10;Q07866;H0YGB8 Q07866-6 KLC1 Kinesin light chain 1 1 S(0.517)RES(0.483)LNVDVVK;S(0.976)RES(0.024)LNVDVVK;S(0.996)RES(0.004)LNVDVVK;S(0.959)RES(0.041)LNVDVVK 154.13 5.6108999999999994e-05 107771400.0 226899.0 265222.0 337470.0 411129.0 395300.0 401217.0 343681.0 417533.0 379600.0 373037.0 True False 299048.16220761323 350949.8248011092 332994.92730101896 316349.5609297314 340419.41837468225 376128.83756442234 374267.9432016826 353012.86880383943 399664.8810312405 359977.08817362593 0.830742211191438 0.9749226723891865 0.9250447826846335 0.8788047109741277 0.945669681650654 1.0448688261598638 1.039699346146063 0.9806537149208022 1.1102508858521356 1.0 18.457545559241204 -6.642633218310412 3.9692481667795265 1.0341826541298866 0.9093703536574151 0.6451105777911068 0.04667985230421349 0.14704777753840154 4.281136030355414 0.015391133786013103 0.015290774058077179 2.2770196669166952e-07 6.642633218310412 -0.1248123004724715 S(ph)RESLNVDVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SRESLNVDVVK 11 1 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;G3V3H3;H0YJT3;F8W6L3;E7EVH7;G5E9S8;H0YJU9;H0YJL0;G3V2E7;Q07866-8;Q07866-2;Q07866-3;Q07866-5;Q07866-10;Q07866;H0YGB8 Q07866-6 KLC1 Kinesin light chain 1 1 S(0.759)RES(0.241)LNVDVVK;S(0.937)RES(0.063)LNVDVVK;S(0.5)RES(0.5)LNVDVVK;S(0.641)RES(0.359)LNVDVVK 77.372 0.009236399999999999 30471100.0 80745.0 101886.0 104781.0 127781.0 133306.0 116437.0 135350.0 108699.0 114452.0 85829.2 True False 94413.53371355588 112000.56873888362 107279.37642415542 120621.84484159149 107185.64624512778 110330.83874437635 122528.66815085881 105845.76642611033 116125.64397808892 101389.3545364265 0.9311976996523398 1.104658070376065 1.058093099760417 1.1896894441541717 1.0571686419664386 1.0881895762018823 1.208496382199943 1.0439534496502072 1.1453435571124784 1.0 16.629546657707564 -4.761334101103161 24.85832993795765 1.1041364867460268 0.9311975347846333 0.39377580980813487 0.06241415938619331 2.2171348783845315 520893.24848629837 0.014434991701416522 0.08085785937016461 1.7324707018085003e-05 4.761334101103161 -0.17293895196139353 S(ph)RESLNVDVVK ddPTM_PC-9_Lapatinib_30min_R1 3 SRESLNVDVVK 11 1 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;G3V3H3;H0YJT3;F8W6L3;E7EVH7;G5E9S8;H0YJU9;H0YJL0;G3V2E7;Q07866-8;Q07866-2;Q07866-3;Q07866-5;Q07866-10;Q07866;H0YGB8 Q07866-6 KLC1 Kinesin light chain 1 1 S(0.894)RES(0.106)LNVDVVK;S(1)RESLNVDVVK;S(0.98)RES(0.02)LNVDVVK 134.06 2.7299e-05 78458000.0 228142.0 233783.0 222479.0 221629.0 273551.0 233220.0 216131.0 236823.0 250914.0 194769.0 True False 224888.65324388098 233241.6898270847 204187.63541377484 237928.33599267036 257461.26800195873 223245.72426237364 227321.20564289493 247826.66114486716 222653.423078444 228434.5621366206 0.9844773537788082 1.021043784467208 0.8938561376349682 1.041560146447418 1.1270679252466973 0.9772852329099672 0.9951261469222866 1.0848912652571754 0.9746923626437971 1.0 17.801421421332 S(ph)REYEHVR ddPTM_PC-9_AZD4547_30min_R2 1 SREYEHVR 8 1 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 S(1)REYEHVR 69.65 0.019008 6640900.0 16208.0 16719.0 18125.0 22454.0 23802.0 20823.0 16689.0 32382.0 18570.0 22940.0 True False 21361.806852656882 22123.08979213546 17884.650657335384 17277.577210841817 20497.50315242649 19520.93451823815 18174.288669123052 27378.105964333194 19551.572288593623 22136.87758239258 0.964987350774701 0.999377157405971 0.8079120729998811 0.7804884472317906 0.9259437369220477 0.881828724289684 0.8209960325921789 1.2367645736140054 0.8832127392774093 1.0 14.434164123164953 -7.723092110049019 24.9998652057906 1.0449928155163024 0.8823134635374018 0.32530302091496843 0.10347956427853636 172.75807066547426 112626.70060512754 0.04776618278631489 0.02757711383605679 1.8919423117256308e-08 7.723092110049019 -0.1626793519789006 S(ph)REYEHVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SREYEHVR 8 1 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 S(1)REYEHVR 64.73 0.025344 2863300.0 6541.9 7353.5 5756.2 5946.7 10358.0 7876.3 8023.5 7251.6 7573.7 6375.4 True False 7649.314461585366 8083.506882411535 5893.4496385100665 5613.525678461524 8328.424255525151 7463.252962566287 7263.45599489042 7061.25318370531 7684.451034467299 7531.20955236137 1.0156820638707318 1.073334479171011 0.7825369348091247 0.745368408544871 1.1058548029531086 0.9909766699063931 0.9644474694789236 0.9375988192349917 1.0203475259904142 1.0 12.878665872674373 -6.285508825153805 24.998572649865825 0.9975349230944832 0.9076168701324963 0.1917359642552272 0.0990453456780684 1626.8135530821273 1689606.643660577 0.033727583553415416 0.03826117254797099 5.181925618814379e-07 6.285508825153805 -0.08991805296198696 S(ph)REYEHVR ddPTM_PC-9_Lapatinib_30min_R1 2 SREYEHVR 8 1 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 S(1)REYEHVR;S(1)REYEHVR 57.785 0.037852 10817400.0 24899.0 21931.0 29531.0 19347.7 26666.0 25350.0 24285.0 26866.0 26067.0 21746.0 True False 24543.935694082633 21880.220116936616 27103.07517295655 20770.594400035166 25097.558307373132 24265.839593736237 25542.358472582404 28114.292439154953 23131.05996232097 25504.767125276394 0.9623273787808267 0.8578874690156381 1.0626670316113633 0.8143808684083438 0.9840340115279979 0.9514236877578732 1.001473894943693 1.1023151986082005 0.9069308435048219 1.0 14.638479307622369 -7.01217763522145 1.992308513704895 1.0103987357160962 0.9309410401528739 0.1421246312284481 0.0769541671840157 0.5858101655988204 4.6625437021284135 0.032759405335551314 0.025172142661815205 9.7234943185841e-08 7.01217763522145 -0.07945769556322224 S(ph)RFSGGFGAR ddPTM_PC-9_AZD4547_30min_R2 3 SRFSGGFGAR 10 1 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A2R8YDT5;A0A0J9YVQ7 A0A2R8Y5G6 1 S(0.985)RFS(0.015)GGFGAR;S(0.977)RFS(0.023)GGFGAR;S(0.999)RFS(0.001)GGFGAR 80.87100000000001 0.0080505 29206800.0 20787.300000000003 25958.6 33653.9 61759.0 60820.0 53471.0 33368.2 56377.0 40311.7 42424.0 True False 27397.22899729978 34349.20980190966 33207.62729693238 47521.41671703836 52376.19282961846 50127.44991714513 36337.905157231224 47665.23006457945 42442.49416403335 40938.7486728606 0.669224875831687 0.8390390746036817 0.8111539402997584 1.1607930935256354 1.2793794272549432 1.22444997812979 0.8876164107409712 1.1643059841782124 1.0367315939035924 1.0 15.32117938540251 -5.720034686086773 6.091623558093426 1.1174239561225847 0.7749428584726079 0.6417166509778413 0.11446828493457062 0.12150452586303898 11.265023528926275 0.032742534423118044 0.056209195113332965 1.9053085393395606e-06 5.720034686086773 -0.3424810976499768 S(ph)RFSGGFGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SRFSGGFGAR 10 1 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A2R8YDT5;A0A0J9YVQ7 A0A2R8Y5G6 1 S(0.971)RFS(0.029)GGFGAR;S(1)RFSGGFGAR;S(0.999)RFS(0.001)GGFGAR 83.226 0.0065276000000000015 23345700.0 29514.2 40337.0 56389.0 53299.0 64619.0 52431.0 54590.0 65260.0 53300.0 46764.0 True False 34510.37112797851 44341.39078205401 57733.5276164734 50312.82982768947 51957.37082137279 49681.426060499616 49418.84000262573 63546.99414868558 54079.411666306674 55241.94301637966 0.6247132023894584 0.8026761616423675 1.0451031311363355 0.9107722697728307 0.9405420588838997 0.8993424805092155 0.8945890985038789 1.1503395912385526 0.9789556397440929 1.0 15.75347644372899 -4.9651140594793945 2.982933151642493 0.9730448517888779 0.6213047655958843 0.6937278022879021 0.07443438032566427 0.16782827231205066 2.7550807534768653 0.02039263392602582 0.1156164474748751 1.0836422778786083e-05 4.9651140594793945 -0.3517400861929936 S(ph)RFSGGFGAR ddPTM_PC-9_Lapatinib_30min_R1 1 SRFSGGFGAR 10 1 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A2R8YDT5;A0A0J9YVQ7 A0A2R8Y5G6 1 S(0.991)RFS(0.009)GGFGAR 75.788 0.011337 8883800.0 16928.0 18904.0 13783.0 15524.0 13260.0 8649.3 10951.0 11361.0 14826.0 11883.0 True False 16686.603615785 18860.22894945831 12649.814943918596 16665.686746545896 12480.072870163034 8279.389601503068 11517.989196345474 11888.87353536959 13156.139755298682 13936.960716897778 1.1972914292248407 1.3532526447169608 0.907645160295344 1.195790609235175 0.8954658855450206 0.594059908016012 0.8264347895004512 0.8530463547159892 0.943974803584515 1.0 13.766628361363768 -5.857958498614461 1.167980853513255 0.8327187486018367 1.2511800679075462 0.5058831934867386 0.14672951664547584 0.4114665151467784 1.1208617230639415 0.05553780927007798 0.13098160576204573 1.3868883542449947e-06 5.857958498614461 0.4184613193057095 S(ph)RFTPELQPK ddPTM_PC-9_AZD4547_30min_R2 3 SRFTPELQPK 10 1 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 S(0.992)RFT(0.008)PELQPK;S(0.992)RFT(0.008)PELQPK;S(0.985)RFT(0.015)PELQPK 86.262 0.0053685 22481100.0 81956.0 98046.0 119167.0 147464.0 122558.0 128993.0 91758.0 121254.0 97819.0 118642.0 True False 108016.30320930103 129737.45210597008 117586.76771766531 113468.45309608874 105542.93720507046 120927.04731840266 99924.28424120048 102516.9804397274 102989.51263855367 114488.37969181444 0.9434695774371576 1.1331931891708473 1.0270629039749821 0.9910914400354762 0.9218659351208938 1.056238612546707 0.8727897495814133 0.8954356827801018 0.8995630204199414 1.0 16.80484164994902 -6.408165436162075 0.8910448466748643 0.9188739996013576 1.0448666874947972 0.2729209210126796 0.06686747991795822 0.6937054688518073 1.1993727543232007 0.03528711074151745 0.04843969986500961 3.9069204079494275e-07 6.408165436162075 0.12599268789343954 S(ph)RFTPELQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRFTPELQPK 10 1 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 S(0.989)RFT(0.011)PELQPK;S(0.997)RFT(0.003)PELQPK 75.89 0.011271 11220400.0 69196.0 76084.0 68474.0 81433.0 86943.0 65839.0 76817.0 57573.0 59014.0 43709.0 True False 80909.51611670313 83637.11669836135 70106.67984909125 76870.573019348 69907.14327554776 62386.286937064564 69540.33765308117 56061.769753635854 59876.968106480745 51633.09569974637 1.567008815183254 1.6198354091477065 1.3577857166800793 1.4887848961518997 1.353921207476451 1.2082616022066446 1.3468171278644203 1.0857720032833753 1.1596625632263777 1.0 15.656008478070644 -6.014966344695755 0.25407780949640996 0.9626513052672895 1.8604570133678557 0.8505332116368449 0.07517957405695609 1.7788334532426524 0.16958924425056934 0.11832073795515734 0.49673342895071876 9.661257452324445e-07 6.014966344695755 0.8978057081005663 S(ph)RFTPELQPK ddPTM_PC-9_Lapatinib_30min_R1 3 SRFTPELQPK 10 1 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 S(0.99)RFT(0.01)PELQPK;S(0.858)RFT(0.142)PELQPK;S(0.999)RFT(0.001)PELQPK 128.36 0.00013311 17160600.0 162186.0 155497.0 175497.0 131637.0 128781.0 125849.0 114148.0 109296.0 131995.0 102424.0 True False 159873.19789873023 155136.95625020692 161068.31409801054 141318.02410815912 121206.35477318741 120466.73163834761 120058.02490954647 114374.29116466446 117128.3331310299 120127.85192859864 1.3308587087177364 1.2914320347825492 1.340807410705604 1.1763968292062315 1.0089779582942164 1.0028209920040059 0.9994187274813365 0.9521046895323328 0.9750306132223892 1.0 16.874211156544312 -6.0860730661457625 2.1830382962517656 0.9839088934352985 1.3207786946138609 0.9806211898317666 0.021042783577378477 0.03860960860435626 0.36367484910066533 0.006938776954989415 0.01013291489822096 8.20213539160244e-07 6.0860730661457625 0.33686980117856236 S(ph)RGQGYVGGQR ddPTM_PC-9_AZD4547_30min_R2 1 SRGQGYVGGQR 11 1 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 S(1)RGQGYVGGQR 94.402 0.032085 2364000.0 5447.3 5827.3 9659.5 11722.0 9107.4 7596.2 7297.5 10000.0 7722.5 8495.3 True False 7179.4280891212975 7710.860765937614 9531.408718594826 9019.674003094671 7842.994715167174 7121.208413170088 7946.963362869286 8454.729777139515 8130.695584203785 8197.88213276807 0.8757662006903135 0.9405918066467722 1.1626672065089183 1.1002444115464634 0.9567098658100532 0.8686644059818366 0.9693922447486983 1.0313309755143696 0.9918044017374034 1.0 13.001035532052024 -3.234333458692889 15.393421964941513 0.9922528666056023 0.5033974343348215 0.0 0.08694168609163834 0.0 0.0 0.02173100134369771 0.0 0.0005829972971341168 3.234333458692889 -0.48885543227078077 S(ph)RGSPSSYNSSSSSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRGSPSSYNSSSSSPR 16 1 Q9H201;I6L9I8 Q9H201 EPN3 Epsin-3 1 S(0.821)RGS(0.17)PS(0.009)S(0.001)YNSSSSSPR 101.42 0.0079204 3739800.0 4701.2 4794.8 5951.9 6144.2 8167.1 4501.6 5115.7 5273.8 6359.8 3956.6 True False 5497.020307067534 5270.796056270731 6093.81586870645 5799.960393765165 6566.8153830179035 4265.528171386109 4631.103861539343 5135.368338052987 6452.8000434404785 4673.900259571634 1.1761098871997195 1.1277082872011914 1.3037967287014705 1.2409251527966356 1.4049969015855202 0.912627128200003 0.9908435363068245 1.0987329752140769 1.380602855233347 1.0 12.190411232185324 -6.760198352022933 24.999953547212765 1.077374767995076 1.2462800366989433 0.2954799258882812 0.13436177129681062 48.27628202789024 972512.5190840996 0.047682232886542227 0.04519955877140846 1.7370073173857382e-07 6.760198352022933 0.16890526870386724 S(ph)RLDSYVR ddPTM_PC-9_AZD4547_30min_R2 1 SRLDSYVR 8 1 Q9Y5R8 Q9Y5R8 TRAPPC1 Trafficking protein particle complex subunit 1 1 S(0.975)RLDS(0.024)YVR 58.246 0.036997 1887600.0 14606.0 11064.0 14152.0 17947.0 19537.0 18700.0 16019.0 14962.0 15650.0 19591.0 True False 19250.404176326916 14640.221631687707 13964.335233247459 13809.596428385947 16824.624783167634 17530.686043848313 17444.65996708504 12649.966692556152 16477.227049891775 18905.12505303631 1.01826378414964 0.7744049082254747 0.7386534177410626 0.7304683988941939 0.8899504624258208 0.9272980736529298 0.9227476633000792 0.6691289614360139 0.8715746128981783 1.0 14.206489772000682 -6.311862848062754 24.981140405743663 0.8680637074643162 0.8070303779270914 0.06881186547653251 0.10963291160789655 1139.2469197894927 564410.6718284393 0.03514257953291338 0.03984802317900692 4.876824778673835e-07 6.311862848062754 -0.061033329537224734 S(ph)RLDSYVR ddPTM_PC-9_Lapatinib_30min_R1 1 SRLDSYVR 8 1 Q9Y5R8 Q9Y5R8 TRAPPC1 Trafficking protein particle complex subunit 1 1 S(0.866)RLDS(0.134)YVR 62.464 0.02918 2896900.0 11993.0 11163.0 12524.0 11481.0 10485.0 12411.0 9305.1 10449.0 10947.0 12117.0 True False 11821.977620753154 11137.15275935268 11494.325064038054 12325.351039493264 9868.29291430313 11880.210461454068 9786.872547796027 10934.498685949899 9714.033582979548 14211.407305112376 0.8318653717355877 0.7836769800656005 0.8088097693113837 0.8672857497412921 0.6943923780689288 0.8359629842697078 0.6886631519086306 0.7694170219170589 0.6835377647282719 1.0 13.794761806162235 -3.4190053290751754 9.228265280091767 0.7871955055038542 0.8224960602408862 0.0 0.09270138473786058 0.0 0.0 0.019643621253501508 0.0 0.0003810611474974743 3.4190053290751754 0.035300554737031975 S(ph)RLSAIEIDIPVVSHTT ddPTM_PC-9_Lapatinib_30min_R1 2 SRLSAIEIDIPVVSHTT 17 1 P56749 P56749 CLDN12 Claudin-12 1 S(0.5)RLS(0.5)AIEIDIPVVSHTT;S(0.682)RLS(0.318)AIEIDIPVVSHTT 126.25 1.7357e-05 23347600.0 82275.0 81722.0 47092.0 31469.0 44058.0 43338.0 26745.0 22699.9 66644.0 20291.5 True False 81101.74341261272 81532.7777299846 43220.277540376854 33783.335237506624 41466.59506136072 41484.534765812256 28129.725235709964 23754.620224059163 59137.8509275681 23798.85873827581 3.4077996892420908 3.425911243334332 1.81606513218491 1.4195359369553606 1.7423774609271416 1.7431312661683436 1.1819779068005813 0.9981411497625515 2.4849028089089176 1.0 14.538604771061342 -5.304548726208341 3.731446275223043 1.5216644393248364 3.4582443547088464 0.7675331876301744 0.4137884910578848 0.0956126783015031 2.796639071044126 0.10728588361217103 0.26582205466629405 4.959652788343193e-06 5.304548726208341 1.93657991538401 S(ph)RLSSSSSNDSGNK ddPTM_PC-9_Lapatinib_30min_R1 2 SRLSSSSSNDSGNK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(0.621)RLS(0.367)S(0.007)S(0.002)S(0.002)S(0.001)NDSGNK;S(0.497)RLS(0.497)S(0.005)S(0.001)SSNDSGNK 87.088 0.0029473000000000004 36928000.0 20617.4 19818.8 21306.4 15232.0 16740.5 17001.3 15523.7 18858.3 22163.0 14568.4 True False 20323.39209523189 19772.91078626344 19554.67003708242 16352.212092462436 15755.856703089323 16274.194030965997 16327.441227952537 19734.525463608872 19666.769553263497 17086.52852882721 1.1894395084960452 1.157222238145329 1.1444495588493082 0.957023661352516 0.9221215811337645 0.9524576044519109 0.9555739306791317 1.1549757126097409 1.1510102546625012 1.0 14.060571693884928 -5.667588675094178 6.0614690861257206 1.0113115858941824 1.167087468315023 0.44934342024477214 0.07650866680929383 0.21826478975654148 11.567705187774482 0.023948595580428746 0.04177935334026816 2.149865670758129e-06 5.667588675094178 0.15577588242084062 S(ph)RLTPVS(ph)PESSSTEEK ddPTM_PC-9_AZD4547_30min_R2 1 SRLTPVSPESSSTEEK 16 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 2 S(0.562)RLT(0.439)PVS(0.999)PESSSTEEK 119.62 0.00034042 201160000.0 56139.0 70494.0 63794.0 79500.0 74781.0 76452.0 57415.0 64965.0 66238.0 72428.0 True False 73990.03423626025 93279.80691469568 62948.0498777409 61172.50326275608 64398.948964020055 71671.44435424019 62524.82377240701 54926.15199718691 69739.20545244284 69892.31776536748 1.0586289967468105 1.3346217423757694 0.9006433309174424 0.8752392998056765 0.9214023947554726 1.025455252390475 0.8945879285661471 0.7858682292033462 0.99780931126882 1.0 16.092846269615293 -5.277713466498474 24.733845655208683 0.9180560686585084 1.1966253663059672 0.586502244334663 0.0910318869278018 387.16976145673567 588432.1173291625 0.022920959015708713 0.0479503497074732 5.275778254674881e-06 5.277713466498474 0.27856929764745875 S(ph)RLTPVS(ph)PESSSTEEK ddPTM_PC-9_Lapatinib_30min_R1 2 SRLTPVSPESSSTEEK 16 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 2 S(0.641)RLT(0.438)PVS(0.911)PES(0.003)S(0.002)S(0.003)T(0.002)EEK;S(0.604)RLT(0.396)PVS(0.856)PES(0.109)S(0.034)S(0.001)TEEK 183.71 2.4305000000000003e-06 252356000.0 126026.0 112286.0 106593.0 107198.0 118246.0 110631.0 101845.0 92850.0 113223.0 92566.0 True False 124228.84612966231 112026.00866583118 97829.33500087881 115081.69852204522 111291.00276058057 105899.57002345695 107118.03576858771 97164.14996558995 100470.63344895348 108565.90976355832 1.1442712210510253 1.0318709520309688 0.9011054686866043 1.0600168945544453 1.0251008166647995 0.9754403592627899 0.9866636405652209 0.8949784529711046 0.9254344542201577 1.0 16.728211635259413 -7.141102249674699 1.5226952306561141 0.9364014666992317 1.0271655080334374 0.27520343273132775 0.06192593434382089 0.5629124015337887 2.584428322219037 0.03462441722022748 0.022889905237026168 7.225996557387818e-08 7.141102249674699 0.09076404133420568 S(ph)RLTPVSPES(ph)SSTEEK ddPTM_PC-9_Lapatinib_30min_R1 2 SRLTPVSPESSSTEEK 16 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 2 S(0.959)RLT(0.041)PVS(0.002)PES(0.932)S(0.061)S(0.004)TEEK;S(0.768)RLT(0.232)PVS(0.38)PES(0.568)S(0.048)S(0.004)TEEK 244.18 2.1284999999999998e-45 149628000.0 591277.0 569552.0 516584.0 493808.0 578961.0 529241.0 493285.0 475690.0 562039.0 439273.0 True False 582845.281553078 568233.2373371704 474112.4575919053 530124.2876151972 544907.6522611204 506606.5961510285 518824.8836379583 497792.2939917217 498736.2492869495 515200.7527555204 1.131297418405864 1.1029355727801424 0.9202479908193907 1.028966446147175 1.0576608231775952 0.9833188197833048 1.0070344052547564 0.9662103390364036 0.9680425477243356 1.0 18.974775175800566 -5.114388383435283 6.367812730211374 0.9944146655905591 1.1243109443793666 0.669392244589494 0.03549273594850374 0.13044344778204162 6.268731377022273 0.009325273578294017 0.025533121405177214 7.684429252354342e-06 5.114388383435283 0.1298962787888075 S(ph)RLTPVSPESSSTEEK ddPTM_PC-9_AZD4547_30min_R2 1 SRLTPVSPESSSTEEK 16 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 S(0.5)RLT(0.5)PVS(0.001)PESSSTEEK 72.315 0.007778 23714000.0 30416.0 38432.0 39815.0 59665.0 47150.0 38644.0 37629.0 49811.0 42569.0 50399.0 True False 40087.65530789809 50854.39242127821 39287.02708534115 45910.156065060866 40604.03636824253 36227.584571041414 40977.9081029679 42113.854492909646 44819.11043366409 48634.546350261706 0.8242629635977343 1.0456434003728412 0.8078008336378724 0.9439824057249343 0.8348805410009553 0.7448940576135644 0.8425679106339068 0.8659246904373157 0.9215488535840516 1.0 15.569693840350821 -1.5237776766897912 21.016837166138245 0.8772280780341924 0.00032290035615523127 0.0 0.08838398230051435 0.0 0.0 0.01986569140755196 0.0 0.029937968238974644 1.5237776766897912 -0.8769051776780372 S(ph)RLTPVSPESSSTEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRLTPVSPESSSTEEK 16 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 S(0.5)RLT(0.5)PVSPESSSTEEK 122.19 2.9426999999999998e-05 150090000.0 83244.0 87007.0 80191.0 116510.0 103210.0 96969.0 106240.0 97948.0 84462.0 76415.0 True False 97335.56505605593 95644.47995076903 82103.05756606093 109982.32243051653 82986.74139918436 91883.7749358316 96176.17808900803 95376.96878448444 85697.09696359475 90268.4345991928 1.0782901629815826 1.059556204507664 0.9095433850228207 1.2183918212258444 0.9193328960190748 1.0178948526559832 1.0654463934823575 1.0565926971922623 0.9493584035671433 1.0 16.461933968490946 -1.5228787487788713 0.11755126554864842 0.9830121454002356 1.2133874466160475 0.04657895000119816 0.08450613425172153 424.438738617949 3.4560881971757498 0.6134850941376775 15.96469109623321 0.029999999758329853 1.5228787487788713 0.23037530121581185 S(ph)RNSPLLER ddPTM_PC-9_AZD4547_30min_R2 3 SRNSPLLER 9 1 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 S(0.962)RNS(0.038)PLLER;S(0.977)RNS(0.023)PLLER;S(0.92)RNS(0.08)PLLER 78.548 0.010117000000000001 509812000.0 92399.0 83577.2 121711.0 173490.0 166054.0 128822.0 117826.0 150723.0 122847.3 135548.3 True False 121779.95998140686 110591.89545877521 120097.03261544525 133494.5608937804 143000.2684006815 120766.73997543447 128312.28574079325 127432.22361997992 129340.75748026633 130802.79527469164 0.9310195529511703 0.8454857193726429 0.9181534107374095 1.0205788080708516 1.0932508598182067 0.923273388170482 0.9809598141334196 0.9742316542423014 0.9888225798894055 1.0 16.997033846204346 -5.6230294173439415 4.873909367391525 0.9961162043175453 0.886817374223316 0.5146721205313862 0.04459534731559643 0.16479379420363804 6.445940139166785 0.012706846581928832 0.022614264220529628 2.3821581061807917e-06 5.6230294173439415 -0.10929883009422936 S(ph)RNSPLLER ddPTM_PC-9_Lapatinib_30min_R1 1 SRNSPLLER 9 1 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 S(0.627)RNS(0.373)PLLER 73.435 0.013966 47958000.0 20633.0 20386.0 19701.0 13768.0 15537.0 15786.0 9224.8 14765.0 18109.0 13179.0 True False 20338.769636371213 20338.797469512112 18081.259828059214 14780.54464870162 14623.144206917284 15110.869578963335 9702.415006706937 15451.035802282544 16069.373723776049 15456.972590086336 1.3158313840457945 1.3158331847309375 1.16978015731593 0.9562380060233426 0.9460548708157867 0.9776086158459657 0.6277047429669242 0.9996159152273065 1.039619733432308 1.0 13.915970159551911 -5.615972554270774 1.9373347986106326 0.9173613965391747 1.3253386413475756 0.67555724699831 0.10832792202033847 0.2000649676525343 1.501099800877568 0.0337723332578478 0.07957221638758263 2.421182051229836e-06 5.615972554270774 0.4079772448084009 S(ph)RPALSPLGDIDFCPPNPGPDGPR ddPTM_PC-9_AZD4547_30min_R2 3 SRPALSPLGDIDFCPPNPGPDGPR 24 1 Q9ULL5;Q9ULL5-2;A0A3Q5ADB5 Q9ULL5 PRR12 Proline-rich protein 12 1 S(0.5)RPALS(0.5)PLGDIDFCPPNPGPDGPR;S(0.58)RPALS(0.42)PLGDIDFCPPNPGPDGPR;S(0.767)RPALS(0.233)PLGDIDFCPPNPGPDGPR 71.37 0.00029343 17516900.0 30542.5 32979.3 45617.0 69407.0 52428.0 49296.0 35348.0 51731.0 43640.0 48434.0 True False 40254.37967653465 43639.21377963832 45012.08877438167 53406.2884774605 45149.27717315419 46213.51332714153 38493.903521850436 43737.162610120424 45946.72130717426 46738.34040216224 0.8612710534897892 0.9336919840144656 0.9630656199401401 1.1426654865774777 0.966000863202782 0.9887709518458548 0.8236044153606619 0.9357876688342367 0.983062747025751 1.0 15.51231888696761 -9.81153211455889 16.085152689472164 0.999994756005562 0.9572749819382012 0.026697687660305447 0.08014908217879947 0.0 0.0 0.08258695888963652 0.020030279694147935 1.5433622928579702e-10 9.81153211455889 -0.04271977406736083 S(ph)RPALSPLGDIDFCPPNPGPDGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SRPALSPLGDIDFCPPNPGPDGPR 24 1 Q9ULL5;Q9ULL5-2;A0A3Q5ADB5 Q9ULL5 PRR12 Proline-rich protein 12 1 S(0.637)RPALS(0.363)PLGDIDFCPPNPGPDGPR;S(0.646)RPALS(0.354)PLGDIDFCPPNPGPDGPR;S(0.567)RPALS(0.433)PLGDIDFCPPNPGPDGPR 75.695 0.00012614 12936000.0 21313.4 25948.9 27437.9 29521.0 34949.4 29251.699999999997 27228.6 28607.0 26005.5 23093.6 True False 24921.337661161655 28524.93530169427 28092.123594815203 27867.034078373323 28101.315956367107 27717.689357325162 24649.309890007236 27856.096561621947 26385.781239927568 27280.286871162985 0.9135291640758041 1.0456244626901985 1.029759097750192 1.021508102535042 1.0300960576067844 1.0160336468684477 0.9035575764440784 1.0211071713863695 0.9672105489410756 1.0 14.735571194931628 S(ph)RPALSPLGDIDFCPPNPGPDGPR ddPTM_PC-9_Lapatinib_30min_R1 3 SRPALSPLGDIDFCPPNPGPDGPR 24 1 Q9ULL5;Q9ULL5-2;A0A3Q5ADB5 Q9ULL5 PRR12 Proline-rich protein 12 1 S(0.914)RPALS(0.086)PLGDIDFCPPNPGPDGPR;S(0.734)RPALS(0.266)PLGDIDFCPPNPGPDGPR;S(0.726)RPALS(0.274)PLGDIDFCPPNPGPDGPR 94.84100000000001 2.9898e-06 16031100.0 23458.6 27068.9 34526.899999999994 25593.5 33045.0 33933.8 28878.9 30391.3 39944.1 26311.1 True False 23124.076062219625 27006.223625158258 31688.231559688225 27475.731367413195 31101.358068969672 32482.530477551365 30374.108136457064 31803.39074689533 35445.174827979645 30858.938577662986 0.7493477458410646 0.8751507624668112 1.0268736716247757 0.8903654057402123 1.0078557300568387 1.052613342348191 0.984288816675086 1.0306054651508973 1.1486193777784817 1.0 14.91340081945301 -3.6641462076167266 0.5195543176342837 1.044318207700907 1.4871232782281827e-14 0.7033141793166369 0.05758476984802853 7.185072909572582 0.6090142674303305 0.03203061297098876 5.879409461275862 0.00021669744581831436 3.6641462076167266 -1.0443182077008921 S(ph)RPTSFADELAAR ddPTM_PC-9_AZD4547_30min_R2 3 SRPTSFADELAAR 13 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;A0A0A0MT65;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 S(0.904)RPT(0.017)S(0.079)FADELAAR;S(1)RPTSFADELAAR;S(0.827)RPT(0.095)S(0.078)FADELAAR 107.53 0.0004708 58894000.0 17086.6 14352.300000000001 20486.9 29474.0 22269.2 21958.2 18444.1 25216.9 17135.1 18576.1 True False 22519.783376641626 18991.400300476456 20215.23032009733 22679.22466876065 19177.50597437257 20585.150282782375 20085.589169043837 21320.207531714954 18040.826404000018 17925.756393124793 1.2562807885350276 1.0594476396968318 1.1277197947334952 1.265175324900599 1.0698296659731397 1.148356020874944 1.1204876786536841 1.1893616684366 1.0064192555310725 1.0 14.1297463755526 -8.272379050119193 23.679894795222502 1.0032095327377324 1.1500330612257246 0.4642004841154329 0.0649042320385382 346.9799094127512 751052.6101192463 0.05740881329658102 0.015475956447994679 5.340979977633067e-09 8.272379050119193 0.14682352848799218 S(ph)RPTSFADELAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SRPTSFADELAAR 13 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;A0A0A0MT65;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 S(0.83)RPT(0.107)S(0.063)FADELAAR;S(0.997)RPT(0.002)S(0.001)FADELAAR;S(1)RPTSFADELAAR 89.663 0.0028285 17899600.0 8380.33 13288.400000000001 13447.5 14206.4 21063.1 16320.4 21834.3 21093.1 18195.899999999998 16382.3 True False 9798.954349937734 14607.584532023871 13768.139399927744 13410.461465770233 16935.936757728497 15464.529493577802 19765.99703735725 20539.428474986835 18461.980614239208 19352.281307784553 0.5063462128362125 0.754824937675327 0.7114478743335257 0.6929654056018608 0.8751390333973665 0.7991062783568115 1.0213781374398623 1.0613440425095901 0.9539950520878788 1.0 14.240216025372858 -6.4912853913174375 0.6477058277110551 1.0340540157827878 0.6079799124795533 0.8031762989558361 0.07424483529536105 0.35179342169759 0.32572675474475865 0.053014671722545884 0.0762178010513027 3.2263732531378973e-07 6.4912853913174375 -0.4260741033032345 S(ph)RPTSFADELAAR ddPTM_PC-9_Lapatinib_30min_R1 1 SRPTSFADELAAR 13 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;A0A0A0MT65;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 S(0.981)RPT(0.007)S(0.012)FADELAAR 92.65 0.0021293 15837000.0 4074.3 3909.1 6260.6 3570.9 5266.2 5692.2 5902.5 6883.0 7413.0 5893.5 True False 4016.199734864886 3900.0487191243883 5745.877634614866 3833.515898173196 4956.452469747556 5448.75787516629 6208.102568845691 7202.809307626872 6578.069877649341 6912.183622404871 0.5810319797996887 0.5642281704558497 0.8312680837919889 0.5546027286872695 0.7170603011300094 0.7882831494095307 0.8981391276590223 1.0420454231395095 0.9516630687193338 1.0 12.754925827917836 -7.113717163390025 1.2890550515445662 1.0040998049612755 0.6384990764522562 0.7967326662985578 0.0784085997619878 0.19623528411271085 0.6519698037525483 0.04576483997625326 0.030043624436384996 7.696315037522563e-08 7.113717163390025 -0.36560072850901926 S(ph)RQPSPLLLLPPPAGLTSDPGPSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRQPSPLLLLPPPAGLTSDPGPSVR 25 1 I3L2J0 I3L2J0 CIC 1 S(0.864)RQPS(0.135)PLLLLPPPAGLTSDPGPSVR 62.052 0.0010366 3521500.0 9210.8 6876.9 10542.0 14058.0 13428.0 15331.0 12915.0 12138.0 13006.0 11976.0 True False 10770.006518407568 7559.593184151207 10793.361260757632 13270.375836650937 10796.87979370454 14527.015371316955 11691.597703497197 11819.390361274074 13196.188145065382 14147.153998036158 0.7612843205002653 0.534354343297641 0.7629351643628052 0.9380244138498153 0.7631838739582048 1.026850727244047 0.8264275419013726 0.8354606419718614 0.9327804127174424 1.0 13.788224232897214 -5.542758191856367 4.772466917782086 0.89128625222519 0.6460549794492062 0.5590368460828812 0.09161856596670412 0.12409920773066946 7.3328102967925215 0.02344584789990074 0.04415340190476996 2.8657731419193476e-06 5.542758191856367 -0.24523127277598378 S(ph)RS(ph)NSSPEMKK ddPTM_PC-9_AZD4547_30min_R2 1 SRSNSSPEMKK 11 2 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 S(1)RS(1)NSSPEMKK 83.99799999999999 0.014946000000000001 4183400.0 2733.1 2386.9 4065.9 5627.5 6186.9 5932.4 4651.6 4174.9 5695.3 4480.9 True False 3602.1689479884367 3158.418746626482 4011.9835093881325 4330.166819008295 5327.955728667651 5561.446090188542 5065.583388656772 3529.7651346579796 5996.341930814607 4324.025054879812 0.8330592219680282 0.7304348856771995 0.9278353983773683 1.0014203812537006 1.2321750362327035 1.2861734193497 1.1714972333335778 0.8163146813116907 1.3867500430062325 1.0 12.07815916722728 -5.749773293683306 2.0148634149291413 1.1451957000800062 0.7872982535029661 0.47641536196738565 0.1516780661513891 0.28046671352813374 2.3215993044684162 0.046090247356772085 0.09179764561569463 1.779207933042929e-06 5.749773293683306 -0.35789744657704003 S(ph)RS(ph)PDSSGSRS(ph)HS(ph)PLRS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 SRSPDSSGSRSHSPLRSK 18 3 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 5 S(0.985)RS(0.894)PDS(0.113)S(0.079)GS(0.276)RS(0.884)HS(0.884)PLRS(0.884)K 43.798 0.04564 0.0 3698.2 3181.2 7122.9 3316.1 8782.1 5346.5 4332.4 5392.9 6620.1 4806.9 True False 3645.46298983318 3173.8341268523436 6537.282657189131 3559.977056185314 8265.554144272915 5117.842658300232 4556.710473403995 5643.473821749379 5874.474625256498 5637.766260208363 0.6466147799640153 0.5629595092037469 1.1595519139077475 0.6314516941420241 1.4661044397338023 0.907778439560757 0.8082474978726035 1.001012379952908 1.0419861970367297 1.0 12.460907950185078 -5.249923296185628 24.522992259841992 0.9951068622937415 0.6047870695508264 0.3698912654221228 0.20722555154928704 596.1673436590019 1269503.9934804726 0.051026661830763695 0.13242180817952845 5.624406530329046e-06 5.249923296185628 -0.39031979274291506 S(ph)RS(ph)PESQVIGENTKQP ddPTM_PC-9_AZD4547_30min_R2 1 SRSPESQVIGENTKQP 16 2 O95218-2 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 2 S(0.992)RS(0.924)PES(0.085)QVIGENTKQP 92.633 0.039258999999999995 0.0 15028.0 10890.0 15435.0 24665.0 22160.0 23636.0 14568.0 19828.0 15489.0 18113.0 True False 19806.591398181627 14409.97953444315 15230.321814950157 18978.865320451292 19083.466509443362 22158.03718355075 15864.523778044495 16764.038202112246 16307.716918579792 17478.869383168123 1.1331734887415008 0.8244228627464734 0.871356234838434 1.085817675296987 1.0918021120874353 1.2677042603733049 0.9076401585403334 0.9591031224397015 0.932996097235206 1.0 14.093324246993786 -4.4345381637358 21.675075839650926 0.9989278217973803 12.16616338827092 0.10379350835652346 0.12223351869256821 1055.646448652698 260077.66497873908 0.03195894167506121 2391.2745212479485 3.6767308259483934e-05 4.4345381637358 11.16723556647354 S(ph)RS(ph)RS(ph)SSSGDRK ddPTM_PC-9_Lapatinib_30min_R1 1 SRSRSSSSGDRK 12 3 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 3 S(1)RS(0.994)RS(0.497)S(0.497)S(0.006)S(0.005)GDRK 63.184 0.039925999999999996 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 S(ph)RS(ph)RS(ph)WSK ddPTM_PC-9_AZD4547_30min_R2 1 SRSRSWSK 8 2 A0A087X0H9;Q5T8P6-3;Q5T8P6-2;Q5T8P6 A0A087X0H9 RBM26 RNA-binding protein 26 3 S(1)RS(1)RS(0.933)WS(0.067)K 51.979 0.038743 0.0 5292.3 7083.6 8172.3 6855.5 7261.9 8364.2 6331.9 8064.8 10030.0 6721.8 True False 6975.141313321574 9373.235172652112 8063.929962314039 5275.070391419169 6253.710534518358 7841.185251762359 6895.426833484345 6818.570470667481 10560.165323349169 6486.471827956686 1.0753367159106006 1.4450436880421618 1.243192011959184 0.8132418564871617 0.9641158861686369 1.2088521248125768 1.0630473724968732 1.0511986564528732 1.6280291664622466 1.0 12.66321825435395 -12.333298868876428 14.557214455783972 1.0964868868263378 1.1462462216693046 0.0 0.2282867247616725 0.0 0.0 0.0 0.052801218306860936 4.641957192393639e-13 12.333298868876428 0.049759334842966796 S(ph)RSAPPNLWAAQR ddPTM_PC-9_AZD4547_30min_R2 1 SRSAPPNLWAAQR 13 1 Q92934;F5H1R6;F5H3B1 Q92934 BAD Bcl2-associated agonist of cell death 1 S(0.799)RS(0.201)APPNLWAAQR 96.604 0.0015199999999999999 36284000.0 20452.0 11612.0 23830.0 35984.0 29880.0 23730.0 10475.0 19988.0 6518.3 21218.0 True False 26955.310571973037 15365.351914963623 23513.998629754613 27688.444747258014 25731.677766343302 22246.159348690955 11407.254707236152 16899.313878546465 6862.844030626805 20475.16427825657 1.3164881221782434 0.7504385169344273 1.1484156273522605 1.3522941438209377 1.2567263156793738 1.0864947917568153 0.5571264070076347 0.8253566930592372 0.335178948376729 1.0 14.321587406628202 -7.1894881930386365 5.484232059674676 0.6655446546276955 1.1516579719655324 0.5177893145832126 0.22359678858625512 0.17974608667454706 10.003038473167043 0.08613631080279004 0.06592737186487077 6.464155675589582e-08 7.1894881930386365 0.4861133173378369 S(ph)RSAQEPAR ddPTM_PC-9_AZD4547_30min_R2 1 SRSAQEPAR 9 1 M0R128;A0A1B0GX60;M0R1D6;M0QZD0;M0QYT3;M0QXK0;M0R080;P25685-2;P25685 M0R128 DNAJB1 DnaJ homolog subfamily B member 1 1 S(0.96)RS(0.04)AQEPAR 63.076 0.027839999999999997 1120800.0 4286.0 4336.2 5316.3 9499.5 9296.0 6556.0 6039.0 9078.0 6165.7 9808.0 True False 5648.858845661864 5737.791850987365 5245.802388391286 7309.537040811962 8005.410860640141 6146.052283607998 6576.459300906831 7675.203691687258 6491.606314473975 9464.624905322857 0.5968391671269481 0.6062355252726879 0.554253595981503 0.7723007635200752 0.8458244188988344 0.6493709307118436 0.6948462687843302 0.810935855193877 0.6858809915248864 1.0 13.208329615952547 -14.522878745233632 0.06758868476252174 2.019693297204677 0.31094814387764586 0.6152052191821624 0.08030125069739512 240.0870255185261 1.16822801038761 39.023609123045254 5.187196334600843 3.000000000322633e-15 14.522878745233632 -1.7087451533270313 S(ph)RSAQEPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRSAQEPAR 9 1 M0R128;A0A1B0GX60;M0R1D6;M0QZD0;M0QYT3;M0QXK0;M0R080;P25685-2;P25685 M0R128 DNAJB1 DnaJ homolog subfamily B member 1 1 S(0.5)RS(0.5)AQEPAR;S(0.5)RS(0.5)AQEPAR 66.663 0.022571 24840000.0 33099.0 17493.5 29932.0 30708.0 56906.0 48036.0 38937.0 83728.0 62759.0 46350.0 True False 38702.00696495115 19230.13906948612 30645.692397742143 28987.530316679266 45755.67780313902 45516.90759745494 35248.60548053197 81530.2287171492 63676.731646636785 54752.8880936019 0.7068486852928885 0.3512168899038084 0.5597091489558013 0.5294246810711448 0.8356760601361914 0.8313151905273428 0.6437761862036081 1.4890580489155303 1.1629839788136707 1.0 15.740647445239054 -7.197031370954767 0.9358239195187636 1.2173283916204474 0.5342689672715024 0.5989472627073873 0.20156465772982982 0.373302250190578 0.6456973661790681 0.14844736255826096 0.09018862969016246 6.3528504082866e-08 7.197031370954767 -0.683059424348945 S(ph)RSAQEPAR ddPTM_PC-9_Lapatinib_30min_R1 2 SRSAQEPAR 9 1 M0R128;A0A1B0GX60;M0R1D6;M0QZD0;M0QYT3;M0QXK0;M0R080;P25685-2;P25685 M0R128 DNAJB1 DnaJ homolog subfamily B member 1 1 S(0.872)RS(0.128)AQEPAR;S(0.885)RS(0.115)AQEPAR 75.566 0.012167 35540000.0 29572.0 39273.0 28813.0 24216.0 65066.0 49170.0 70910.0 50472.0 51164.0 74537.0 True False 29150.29785715938 39182.06578142592 26444.1063613964 25996.925422207896 61238.945804677816 47067.113720868314 74581.3728347053 52817.11337709479 45401.37153919476 87420.62113569054 0.33344876161327586 0.4482016402126587 0.30249277593613744 0.2973774961156657 0.7005091591562287 0.538398299044487 0.8531324974109173 0.604172250104633 0.5193439596902967 1.0 16.415686008258675 -6.2650002793407324 24.952546394077917 0.6821185882889006 0.34966116788998525 0.6043524956205202 0.14099319640687857 217.18945536410354 1521924.905095041 0.04157002112944159 0.04901691536255786 5.432499820707781e-07 6.2650002793407324 -0.33245742039891535 S(ph)RSASQER ddPTM_PC-9_AZD4547_30min_R2 1 SRSASQER 8 1 F8W9Z1;J3KP11;Q15878-2;Q15878-3;Q15878 F8W9Z1 CACNA1E Voltage-dependent R-type calcium channel subunit alpha-1E 1 S(0.991)RS(0.004)AS(0.004)QER 64.567 0.025553 3328400.0 0.0 0.0 842.42 1362.3 899.61 0.0 716.09 1773.8 983.14 773.63 True False 0.0 0.0 831.2489603725498 1048.2427823251887 774.7146798989321 0.0 779.8206227498553 1499.699967869008 1035.1067732799106 746.5454491746452 0.0 0.0 1.1134606222455041 1.4041245358659538 1.037732774013196 0.0 1.0445722006771294 2.008852869610316 1.386528810033319 1.0 9.544086283092245 -5.262425259270651 9.060007499845415 1.1246830721833634 1.920071177715982e-10 0.4764511636109183 0.47147695566184245 0.08960692429165074 136.97716176743722 0.13625637391582432 0.3166800335537992 5.464805893991332e-06 5.262425259270651 -1.1246830719913563 S(ph)RSAVTLPR ddPTM_PC-9_AZD4547_30min_R2 3 SRSAVTLPR 9 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.593)RS(0.401)AVT(0.006)LPR;S(0.847)RS(0.152)AVT(0.001)LPR;S(0.643)RS(0.356)AVT(0.001)LPR 99.215 0.0019876 26489200.0 33244.0 30204.0 51636.0 70454.0 51405.0 54231.0 43062.0 44038.0 36955.0 41034.0 True False 43814.9004818439 39966.85232858781 50951.27290163696 54211.91880344927 44268.30306488884 50839.92699700203 46894.43457785233 37232.93899256702 38908.36585487222 39597.412149777556 1.106509190957067 1.0093299071518322 1.2867323932410868 1.3690773174366095 1.1179594994097997 1.2839204442123533 1.1842802858043784 0.9402871796705579 0.9825987038673384 1.0 15.273118527008911 -7.7531387924066335 20.674193010282018 0.9710821797806392 1.1977098557841244 0.5106637086870175 0.09848163819887513 17.86246982894162 44493.23284592377 0.05108447724086761 0.028653792506839106 1.7654735181517976e-08 7.7531387924066335 0.2266276760034852 S(ph)RSAVTLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRSAVTLPR 9 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.931)RS(0.068)AVT(0.001)LPR 68.536 0.020191999999999998 6983000.0 6175.3 7265.8 8001.3 9488.9 11522.0 10510.0 11745.0 9950.0 8940.9 13972.0 True False 7220.65632226541 7987.1006060006475 8192.081337099224 8957.267696428866 9264.346811369063 9958.837098202419 10632.428573563646 9688.823042896436 9071.643747979011 16505.012997708847 0.43748261956944534 0.48391967986389234 0.49633898126807974 0.5426998268751605 0.5613050297297614 0.6033825662291123 0.644193892791214 0.5870230483454569 0.5496296033961497 1.0 14.010616654233662 -14.522878745273951 0.1652519589601679 2.7081506567911875 0.436190193888344 0.9122650163070362 0.04385362479537189 38.5120186267073 0.35789423744865756 21.57721916320232 0.18588415492805233 3.000000000044114e-15 14.522878745273951 -2.2719604629028436 S(ph)RSAVTLPR ddPTM_PC-9_Lapatinib_30min_R1 3 SRSAVTLPR 9 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.499)RS(0.499)AVT(0.002)LPR;S(0.905)RS(0.094)AVT(0.001)LPR;S(0.847)RS(0.152)AVT(0.001)LPR 92.866 0.0031603 28156900.0 65403.0 54157.0 64770.0 46891.0 48685.0 52132.0 58884.0 48482.0 49091.0 36066.1 True False 64470.341226558754 54031.60279389617 59444.86061943027 50339.520563790495 45821.44401839276 49902.435885627536 61932.7253983752 50734.6507122426 43561.854628852525 42300.07732994255 1.524118755710235 1.277340520501823 1.4053132847904184 1.1900574122155834 1.0832472872563184 1.1797244599906105 1.4641279474573319 1.199398533400069 1.0298291960335688 1.0 15.368372680327834 -1.5228787452803376 0.12447221422440535 0.9596597117277891 2.4604237695289215 0.46339086741291746 0.1255138641806874 98.18466941710487 0.8374667631120086 0.839917126193058 25.671097782790362 0.029999999999999995 1.5228787452803376 1.5007640578011325 S(ph)RSDIDVNAAAGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SRSDIDVNAAAGAK 14 1 E3W994;J3KR49;O75122;A0A0U1RQI6;B3KR06;E7ENG2;O75122-2;E7ERI8;E7EW49;O75122-3 E3W994;E7ERI8 CLASP2 CLIP-associating protein 2 1 S(0.5)RS(0.5)DIDVNAAAGAK;S(0.838)RS(0.162)DIDVNAAAGAK;S(0.5)RS(0.5)DIDVNAAAGAK 152.94 0.0012456 73701000.0 126540.0 154200.0 158349.0 178359.0 200833.0 181218.0 178091.0 156316.0 159758.0 133277.0 True False 147960.72272107672 169507.95692770227 162124.64070192655 168366.12347767956 161481.2153417537 171714.6090639436 161220.93121281586 152212.87063049246 162094.15851755752 157439.0650798482 0.9397967565803039 1.0766575426609215 1.0297612007521892 1.0694050005460176 1.025674379226372 1.090673455008484 1.024021141964033 0.9668049702486153 1.029567588167196 1.0 17.264434033098354 -7.529164335169578 24.906659640285344 0.9979943660969861 1.0421707388627979 0.15319803996004833 0.04142920010999281 259.7457060864233 1029222.2161279086 0.018390521802652514 0.010648256063523208 2.95689337906128e-08 7.529164335169578 0.04417637276581177 S(ph)RSESDLSQPESDEEGYALSGR ddPTM_PC-9_AZD4547_30min_R2 2 SRSESDLSQPESDEEGYALSGR 22 1 Q15751;H0YNB1 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 S(0.443)RS(0.428)ES(0.129)DLSQPESDEEGYALSGR;S(0.438)RS(0.28)ES(0.28)DLS(0.001)QPESDEEGYALSGR 152.88 6.6449e-07 10805900.0 3409.3 5516.7 11349.3 11927.4 13125.8 12982.1 12479.8 12987.3 7908.200000000001 8171.7 True False 4493.386482154688 7299.865390051662 11198.800866499118 9177.722206493034 11303.509237800161 12170.32723475098 13590.478023423928 10980.411203464413 8326.211307089716 7885.611270271899 0.5698209470576342 0.9257196607663821 1.4201563433284707 1.1638567882609538 1.4334347522827373 1.5433587603578818 1.7234526985446141 1.3924616402103986 1.055873922986648 1.0 12.945006877649812 -4.954226281726592 1.8110194692715142 1.3812287761099302 0.4397114719262556 0.5711936550060769 0.2133117550883128 0.4207992114510144 1.865434173294715 0.06072153185371671 0.6092508720414537 1.1111526293194878e-05 4.954226281726592 -0.9415173041836746 S(ph)RSESETSTMAAK ddPTM_PC-9_AZD4547_30min_R2 2 SRSESETSTMAAK 13 1 A0A087WVF1;Q96B23-2;Q96B23 A0A087WVF1 C18orf25 Uncharacterized protein C18orf25 1 S(0.873)RS(0.126)ESETSTMAAK;S(0.596)RS(0.364)ES(0.038)ET(0.001)STMAAK 68.257 0.015684 18125000.0 57593.0 57072.0 74516.0 96444.0 76875.0 76101.0 73078.0 88983.0 72128.0 72548.0 True False 75906.37599118151 75519.40789621123 73527.8691521106 74210.32584494642 66202.23320909105 71342.3924397275 79581.80042915525 75232.72197592049 75940.53882776949 70008.11660189265 1.0842510793831213 1.0787236046594286 1.0502763496729006 1.0600246006752332 0.9456365407679214 1.0190588734935169 1.1367510553341151 1.0746285663380724 1.0847390633233585 1.0 16.095234574499464 -10.264202680272097 14.059237566284109 1.0000025359248854 1.057863787996594 0.1226986172909229 0.047456269354986244 0.0 0.0 0.05001919106396436 0.012131435768510359 5.442485989629083e-11 10.264202680272097 0.05786125207170856 S(ph)RSESETSTMAAK ddPTM_PC-9_Lapatinib_30min_R1 1 SRSESETSTMAAK 13 1 A0A087WVF1;Q96B23-2;Q96B23 A0A087WVF1 C18orf25 Uncharacterized protein C18orf25 1 S(0.488)RS(0.488)ES(0.024)ETSTMAAK 89.43 0.0028829999999999997 11285000.0 34801.0 38305.0 36782.0 33589.0 43393.0 53452.0 46975.0 46550.0 51989.0 38286.0 True False 34304.73135827821 38216.30712595217 33757.925942625945 36059.24710961929 40840.70905392042 51165.982562697805 49407.13564955973 48712.88293912985 46133.45135155964 44903.684087111724 0.7639625134482978 0.8510728663557704 0.7517852182715484 0.8030353821228898 0.9095180024581222 1.1394606835251517 1.1002913603639168 1.0848304304971592 1.0273867788233635 1.0 15.454546194140978 -6.545175402690654 3.4162798404473835 1.076981899428781 0.7962773637469325 0.8947037359270881 0.04491661299574606 0.07033375884962506 1.7310671381141145 0.015346618910093016 0.01605292369883611 2.849867031823185e-07 6.545175402690654 -0.2807045356818485 S(ph)RSESK ddPTM_PC-9_Lapatinib_30min_R1 1 SRSESK 6 1 P42261-3;P42261-4;P42261-2;P42261;P42261-6;P42261-5 P42261-3 GRIA1 Glutamate receptor 1 1 S(0.996)RS(0.004)ESK 76.035 0.022624000000000002 0.0 11889.0 11971.0 16116.0 12206.0 14285.0 16685.0 12647.0 12156.0 18177.0 11840.0 True False 11719.460679824428 11943.281884996046 14791.004689559031 13103.669958022358 13444.784385390578 15971.42144463469 13301.799777753742 12720.812137659785 16129.714847704305 13886.52822419169 0.8439446124055674 0.8600624786971361 1.0651333760868793 0.943624622833696 0.9681890367650317 1.1501378304773768 0.9578923949170179 0.916054173677398 1.1615368929726269 1.0 13.761398335254306 -5.246918375074757 22.263473528455478 1.0151286717395744 0.8520033435208447 0.417549765609347 0.07932842454006934 182.81585987641685 280284.9101471683 0.019828538317474758 0.05175020949933471 5.663457227721602e-06 5.246918375074757 -0.16312532821872971 S(ph)RSEVDLTR ddPTM_PC-9_AZD4547_30min_R2 1 SRSEVDLTR 9 1 A0A0B4J281;H0YMG3;H0YKK3;H0YN74;H0YMR9;H0YMV5;H0YNH0;H0YMB3;H0YLV5;A0A087WWM4;F8WAN9;H0YNJ6;Q9P2T1-3;Q9P2T1;Q9P2T1-2 A0A0B4J281 GMPR2 GMP reductase;GMP reductase 2 1 S(0.872)RS(0.128)EVDLTR 69.815 0.018566 4279500.0 4561.0 3573.6 4512.4 11697.0 7578.1 10037.0 7660.3 9061.0 6148.8 7285.9 True False 6011.303125306525 4728.696314443162 4452.562627650218 9000.437366848515 6526.0116225276515 9409.38480332115 8342.051860032561 7660.83065106612 6473.813014976009 7030.822858655362 0.8549928288843534 0.6725665557939431 0.633291823327457 1.2801399704969725 0.9282002624335417 1.338304917146026 1.1864972319367992 1.089606551761602 0.9207760094547623 1.0 12.77947783094853 -5.754181686025388 24.99999898330933 1.115549331115867 0.7155119426680078 0.6132111929017132 0.14030834081757526 105.85477727569831 364625.2441391449 0.03792342900529916 0.06400617808509794 1.7612390822425594e-06 5.754181686025388 -0.4000373884478593 S(ph)RSEVDLTR ddPTM_PC-9_Lapatinib_30min_R1 2 SRSEVDLTR 9 1 A0A0B4J281;H0YMG3;H0YKK3;H0YN74;H0YMR9;H0YMV5;H0YNH0;H0YMB3;H0YLV5;A0A087WWM4;F8WAN9;H0YNJ6;Q9P2T1-3;Q9P2T1;Q9P2T1-2 A0A0B4J281 GMPR2 GMP reductase;GMP reductase 2 1 S(0.845)RS(0.155)EVDLTR;S(0.878)RS(0.122)EVDLTR 73.632 0.019683000000000003 0.0 13067.6 9483.8 12136.7 10271.7 13294.2 13750.8 12333.2 11135.8 14585.099999999999 10843.6 True False 12881.25362769566 9461.840843782938 11138.867375016822 11027.115083386714 12512.261293402822 13162.710338680403 12971.752749188938 11653.209921236563 12942.372450088138 12717.901811811222 1.0128442425725235 0.7439781328548746 0.8758415924136215 0.8670545854620249 0.983830625408869 1.0349749930020755 1.019960127160438 0.9162839982310705 1.0176499741544198 1.0 13.634573055251849 -6.276707145657679 4.981934196113773 0.9953032224945013 0.8649107419367403 0.4311540633049278 0.06753131418795738 0.16885610703676882 12.590254943246007 0.02026201137496688 0.024228144670303684 5.288017142287338e-07 6.276707145657679 -0.13039248055776098 S(ph)RSFDYNYR ddPTM_PC-9_AZD4547_30min_R2 1 SRSFDYNYR 9 1 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 1 S(0.736)RS(0.264)FDYNYR 92.611 0.033277999999999995 19290000.0 58254.0 51513.0 60131.0 59635.0 59920.0 61983.0 43359.0 45241.0 42449.0 58215.0 True False 76777.5602415273 68163.56985838113 59333.62365110259 45887.07210156547 51601.14229448766 58107.19321154281 47217.86700248706 38250.04298475688 44692.76747864892 56176.91056926694 1.3667102634072315 1.2133734156550753 1.0561923582099335 0.816831535172908 0.9185471712771158 1.0343607831529968 0.8405208923738651 0.6808854847507861 0.7955718288128731 1.0 15.777689665655732 -5.157843009799953 1.1333207346573162 0.8548039358414857 1.4590699183541407 0.7440853898150762 0.09937850938590208 0.49962644435022185 0.8205637249122673 0.035210547386811876 0.3086687151381682 6.952756026837354e-06 5.157843009799953 0.604265982512655 S(ph)RSFDYNYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRSFDYNYR 9 1 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 1 S(0.972)RS(0.028)FDYNYR 64.711 0.025051 9325300.0 29905.0 23354.0 18604.0 24724.0 21831.0 14816.0 14294.0 27612.0 15672.0 12440.0 True False 34967.32584932667 25672.430778790935 19047.58991606291 23338.794436289485 17553.372265144764 14039.022877922638 12939.968840401769 26887.214257332304 15901.173351488911 14695.273525014185 2.379494725961075 1.7469855688695766 1.2961711725637663 1.5881837378911228 1.194491020209018 0.9553427402372279 0.8805531124259409 1.8296504799019282 1.0820603865877048 1.0 13.843064591856763 -2.509319616388398 0.6946764310572061 1.1904912741576767 32.445649476658296 0.6528079124623949 0.26881068507800837 39.5883483248845 0.9552127295371841 0.10977319602687124 1780.1014384418847 0.0030951406108765886 2.509319616388398 31.25515820250062 S(ph)RSFDYNYR ddPTM_PC-9_Lapatinib_30min_R1 2 SRSFDYNYR 9 1 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 1 S(0.977)RS(0.023)FDYNYR;S(0.884)RS(0.116)FDYNYR 82.48899999999999 0.007407899999999999 10977600.0 36387.0 42626.0 45689.0 32619.0 41506.0 45222.0 35241.0 32540.0 48510.0 40578.0 True False 35868.11470744142 42527.30211593365 41932.62678464023 35017.910073794155 39064.69868393569 43287.96047763081 37065.60654446268 34051.92719311031 43046.29296705375 47591.85323321371 0.753660811056829 0.8935836540665414 0.8810883362570134 0.7357963116543574 0.8208274322184403 0.9095666072406848 0.7788225090296567 0.7154990797741393 0.90448868961069 1.0 15.538427013882067 -8.524217808896159 24.088914306342716 1.0000000037055412 0.8158189597711836 0.47038344543838895 0.06389148671552174 69.89088039711423 1257306.9190499333 0.06293377364973862 0.01624943051789662 2.990764321775627e-09 8.524217808896159 -0.18418104393435764 S(ph)RSFTLDDESLK ddPTM_PC-9_AZD4547_30min_R2 2 SRSFTLDDESLK 12 1 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 S(0.807)RS(0.192)FT(0.001)LDDESLK;S(0.801)RS(0.199)FTLDDESLK 123.72 0.0016579999999999998 134319000.0 362791.0 379665.0 465660.0 569450.0 580090.0 502690.0 448610.0 605930.0 491550.0 570740.0 True False 478150.9914784207 502384.2864962676 459485.04414316063 438172.1004147977 499554.51658226596 471256.7148332679 488535.42092727544 512297.4413862144 517532.32948078634 550758.5663197362 0.8681680516991468 0.912167902994748 0.8342767089643635 0.7955792741322923 0.9070299531069947 0.855650267924631 0.8870228277914104 0.93016699642 0.9396718655490494 1.0 19.071060503747248 -8.159716095726203 0.8644654141200733 0.997117611157047 0.8591273473502272 0.6656541688111204 0.031964715503372786 0.3537609198433004 0.5417585856668531 0.03150775386907822 0.011950888335739342 6.922833781927062e-09 8.159716095726203 -0.13799026380681978 S(ph)RSFTLDDESLK ddPTM_PC-9_Lapatinib_30min_R1 1 SRSFTLDDESLK 12 1 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 S(0.499)RS(0.499)FT(0.002)LDDESLK 89.46600000000001 0.0035275 27799000.0 66808.0 53588.0 79736.0 58351.0 68756.0 120330.0 110280.0 96976.0 122770.0 118820.0 True False 65855.30566891332 53463.92027843688 73180.41386986095 62642.3271932298 64711.90725949706 115183.76640293039 115989.75879581581 101481.85898829324 108942.34977458649 139357.87868230173 0.47256248653903243 0.38364476256358754 0.5251257737403746 0.4495068939448868 0.4643577232330201 0.826532145093269 0.8323157606341087 0.7282104172929069 0.7817451787060105 1.0 17.088435042824514 -6.759843825792242 24.622261404029008 0.8166835902853075 0.4579927346019615 0.8675856158253489 0.07304363618790796 12.05865288547169 186087.60555677244 0.02389159003031038 0.022694630119170427 1.73842586195401e-07 6.759843825792242 -0.35869085568334597 S(ph)RSGEGEVSGLMR ddPTM_PC-9_AZD4547_30min_R2 1 SRSGEGEVSGLMR 13 1 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 S(0.969)RS(0.031)GEGEVSGLMR 132.86 2.4036999999999997e-05 14986000.0 12765.0 7378.1 15458.0 21788.0 19122.0 19255.0 15866.0 22994.0 13977.0 14321.0 True False 16824.004471505752 9762.926538390728 15253.016819922219 16765.113221244388 16467.240369746203 18050.981806112275 17278.04326348531 19440.80564955462 14715.795685388965 13819.626148973151 1.217399392005683 0.7064537371089556 1.10372137824116 1.213137970631 1.191583635637624 1.3061845242067947 1.2502540283818844 1.4067533694461873 1.0648475962196997 1.0 13.754430967756248 -5.514773549378133 6.47281196272112 1.222897673187856 0.9472925505925852 0.2675997189786329 0.15759196881200904 0.1495913302916633 29.516927984688063 0.039622295853707634 0.07581397006641638 3.0565144311205597e-06 5.514773549378133 -0.2756051225952708 S(ph)RSLGPGAGPR ddPTM_PC-9_AZD4547_30min_R2 3 SRSLGPGAGPR 11 1 H3BUV2;P78549-3;P78549-2;P78549 H3BUV2 NTHL1 Endonuclease III-like protein 1 1 S(0.963)RS(0.037)LGPGAGPR;S(0.976)RS(0.024)LGPGAGPR;S(0.943)RS(0.057)LGPGAGPR 110.15 0.00093056 32522800.0 20035.1 20809.1 26000.0 55526.0 34985.6 32016.699999999997 20794.4 37492.4 24437.6 32982.1 True False 26405.845044031736 27535.234630870622 25655.2230119018 42725.33856814832 30128.453335414346 30014.690687704737 22645.061315909443 31698.81106964256 25729.32164565081 31827.406717969916 0.8296574483123962 0.8651422616635646 0.806073307801629 1.342407157037566 0.9466197985399692 0.9430454373387037 0.71149564639597 0.9959595938975843 0.8084014470184246 1.0 14.957981991203127 -7.022027474859023 24.600510623395387 0.8712907695777132 0.9636494222090818 0.050960514205465435 0.16057182236991946 2010.743025779043 2245612.707422383 0.06293623391183226 0.049206123851072175 9.505446572565525e-08 7.022027474859023 0.09235865263136855 S(ph)RSLGPGAGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRSLGPGAGPR 11 1 H3BUV2;P78549-3;P78549-2;P78549 H3BUV2 NTHL1 Endonuclease III-like protein 1 1 S(0.999)RS(0.001)LGPGAGPR;S(1)RSLGPGAGPR 79.089 0.0083361 11855200.0 18621.4 11394.1 17532.0 18067.9 26955.4 22815.0 20474.4 24257.4 22908.4 18358.4 True False 21773.63523058526 12525.23094701642 17950.029370480246 17055.614139922145 21673.68287095796 21618.54123648793 18534.91661018063 23620.66895283981 23243.392011565105 21686.632594985578 1.0040118093585353 0.5775553623715896 0.8277001646918057 0.786457467069635 0.9994028706867745 0.9968602152409133 0.8546701074497987 1.0891810358008933 1.0717842850779646 1.0 14.404518434603405 -6.26065141290367 9.9688843300974 0.9988713931833235 0.7850950933233035 0.43571231354455375 0.11273229053979761 0.08861428697587859 244.06808242032542 0.03332793476185153 0.040403623204696947 5.487172168834398e-07 6.26065141290367 -0.21377629986002 S(ph)RSLGPGAGPR ddPTM_PC-9_Lapatinib_30min_R1 1 SRSLGPGAGPR 11 1 H3BUV2;P78549-3;P78549-2;P78549 H3BUV2 NTHL1 Endonuclease III-like protein 1 1 S(0.999)RS(0.001)LGPGAGPR 96.756 0.0026766999999999997 10368000.0 14061.0 8250.0 13489.0 7117.3 8225.5 8029.3 8763.9 4944.0 12464.0 5998.3 True False 13860.487561528409 8230.897631878493 12379.986489045772 7640.729984616795 7741.692261955213 7685.9055562124795 9217.651859907966 5173.7162889593565 11060.173068261349 7035.0981627676465 1.9701910678209522 1.1699762308135886 1.7597460906182179 1.0860871885277135 1.1004384136282739 1.0925086442843324 1.3102378455344383 0.7354149393878519 1.5721419676552482 1.0 12.7803548386072 -1.5228787452814605 0.5496065416759305 1.1156725784534114 34.409686337954604 0.4112730221676115 0.27503260210191355 131.0180395761281 1.2014660323994504 0.12800067383771685 5148.654572757349 0.02999999999992243 1.5228787452814605 33.29401375950119 S(ph)RSLSGTGR ddPTM_PC-9_AZD4547_30min_R2 1 SRSLSGTGR 9 1 Q6ICG6-2;B0QY16;Q6ICG6-3;Q6ICG6 Q6ICG6-2 KIAA0930 Uncharacterized protein KIAA0930 1 S(0.999)RS(0.001)LSGTGR 66.568 0.032438 0.0 475.15 405.48 957.53 5638.8 4107.3 1849.1 735.21 2167.0 859.04 1150.9 True False 626.237816266037 536.5434804064288 944.8325265610124 4338.861778591555 3537.0722921586985 1733.4754846887663 800.6422657095069 1832.1399427061342 904.447100635082 1110.6073413066963 0.5638696891101319 0.4831081701433318 0.850734991044954 3.9067468917381936 3.184809032503891 1.5608356078839063 0.7209048922434667 1.649673898743107 0.8143716208205014 1.0 10.11713312219974 -5.545143873515669 24.979074617407203 1.8994512705878759 0.5593453348961408 0.24936630185442044 0.9612306780868805 318.12536976074136 356900.8066062915 0.2881300904957882 0.49909875924948693 2.8500739357139514e-06 5.545143873515669 -1.340105935691735 S(ph)RSPAPPADK ddPTM_PC-9_AZD4547_30min_R2 1 SRSPAPPADK 10 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 S(0.74)RS(0.26)PAPPADK 62.081 0.028810000000000002 6614100.0 26481.0 31371.0 28838.0 25814.0 27872.0 36975.0 30857.0 40385.0 37035.0 31624.0 True False 34901.40716098266 41511.06225665899 28455.589277585543 19862.98112232433 24002.453905740316 34662.947404881925 33603.21322207024 34144.426204977965 38992.594491548974 30516.853385596474 1.1436764701781355 1.3602667919967013 0.9324548936298976 0.6508856228178289 0.7865310883286918 1.1358624353204891 1.1011362409313958 1.1188711291280657 1.277739680394209 1.0 14.89731859208138 -6.892746530195577 23.097388547500184 1.1326148272976484 0.9743601010532233 0.13812505837859956 0.18950078432910034 12.992177091209344 2746.7186046461784 0.07624441357353885 0.06724126664582997 1.280128214820464e-07 6.892746530195577 -0.15825472624442505 S(ph)RSPAYSR ddPTM_PC-9_AZD4547_30min_R2 2 SRSPAYSR 8 1 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 S(0.998)RS(0.002)PAYSR;S(0.981)RS(0.019)PAYSR 60.59 0.032654 11572800.0 2439.6 2053.64 4766.4 7536.099999999999 5581.9 7302.5 3372.6000000000004 4908.2 3852.2999999999997 4968.1 True False 3215.3420531676798 2717.4389688809756 4703.194421689565 5798.768576584347 4806.949535607487 6845.873520599057 3672.7548664080778 4149.750469215619 4055.9247133736776 4794.168331171953 0.6706777549426758 0.5668217678574268 0.981024047718377 1.2095463020938224 1.002665989917882 1.4279585212072763 0.7660880079090295 0.8655829713432688 0.8460121616927438 1.0 12.227064849945235 -5.298220049193533 6.308591058599306 1.0215822731877318 0.6182981066024343 0.4299106339178047 0.1812066746908947 0.17155164171094073 21.026237041176667 0.050062515753149066 0.10896832778592133 5.032455587161864e-06 5.298220049193533 -0.4032841665852974 S(ph)RSPAYSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRSPAYSR 8 1 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 S(0.996)RS(0.004)PAYSR 69.628 0.019038 9504200.0 4421.2 2266.0 2690.3 2431.0 3136.6 3183.5 3097.9 3187.1 1228.8 3291.0 True False 5169.62183731962 2490.9535045277125 2754.4469550195654 2294.798951408338 2522.0057462714976 3016.5516557685446 2804.4444851462613 3103.442002011582 1246.7688753387936 3887.632248458335 1.3297610234017545 0.6407379467323628 0.708515306742776 0.5902819003310703 0.6487253899263786 0.7759354442449583 0.7213759702344226 0.7982858983748454 0.3207013409854308 1.0 11.924676037963147 -4.759164018263315 24.996305734255003 0.6830248913418839 1.3297618616015328 0.5796636465462164 0.1635101121833447 40.53870881221002 445242.3485139233 0.03772817162045045 0.24481773807279453 1.7411491763456084e-05 4.759164018263315 0.6467369702596488 S(ph)RSPAYSR ddPTM_PC-9_Lapatinib_30min_R1 1 SRSPAYSR 8 1 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 S(0.992)RS(0.008)PAYSR 64.82 0.025227 8184800.0 4495.2 2952.4 4197.0 3760.6 5568.1 4578.8 3896.2 3927.1 4636.8 2603.0 True False 4431.097623681279 2945.563899194914 3851.9388608885115 4037.1670689938464 5240.595305305791 4382.975397704125 4097.926171746984 4109.567402583393 4114.554756331371 3052.92508172052 1.4514269119188703 0.9648333386336814 1.2617207293923163 1.3223931020012591 1.716581692975046 1.4356642499835062 1.3422950324865288 1.3461081725161061 1.3477418037433642 1.0 11.575976471142106 -3.431451153785785 12.130150654809857 1.3321080950588282 45.228329108227456 0.0 0.20580580393425094 0.0 0.0 0.048250193317125295 0.0 0.0003702958511821676 3.431451153785785 43.89622101316863 S(ph)RSPFSTTR ddPTM_PC-9_AZD4547_30min_R2 2 SRSPFSTTR 9 1 K7EPI8;Q8NG27-2;Q8NG27-3;Q8NG27 K7EPI8 PJA1 E3 ubiquitin-protein ligase Praja-1 1 S(0.916)RS(0.083)PFSTTR;S(0.5)RS(0.5)PFS(0.001)TTR 80.737 0.008612 31112000.0 43985.0 26375.0 53578.0 71892.0 57986.0 68310.0 55848.0 58397.0 45608.0 62438.0 True False 57971.31505516496 34900.20295876385 52867.52071275671 55318.41012032778 49935.64481121763 64038.564901351776 60818.36380808825 49373.08547956163 48018.74576942261 60252.064624648134 0.9621465325098559 0.5792366315773808 0.8774391556887741 0.9181164241415543 0.8287789824680925 1.0628443240956533 1.0093988344958464 0.8194422180740328 0.796964320950073 1.0 15.878723057783453 -5.5031508728791465 24.351616832679813 0.9162559910354593 0.7601031348395284 0.1939578249393863 0.11915121135991547 788.6089983528325 973437.7745580013 0.03093498666238534 0.06291227737586515 3.139417878044235e-06 5.5031508728791465 -0.1561528561959309 S(ph)RSPFSTTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRSPFSTTR 9 1 K7EPI8;Q8NG27-2;Q8NG27-3;Q8NG27 K7EPI8 PJA1 E3 ubiquitin-protein ligase Praja-1 1 S(0.967)RS(0.033)PFSTTR 63.943999999999996 0.026128 13352000.0 19460.0 24680.0 30842.0 26959.0 20018.0 22243.0 26043.0 17346.0 16467.0 15396.0 True False 22754.193647480268 27130.06729556223 31577.390248936335 25448.574632257256 16095.616600415371 21076.537923436386 23576.018505007916 16890.6858796062 16707.798722496675 18187.17292533107 1.2511121844444695 1.4917143751228927 1.7362451205902039 1.399259507606733 0.8849982713914496 1.158868286454846 1.2962992435273581 0.928714206927723 0.9186583748387895 1.0 14.150633682649637 -6.119811818993303 5.376056247029016 1.0490426168632485 1.503817188279849 0.6465592272246575 0.1592440063399651 0.1518985234098059 6.0751515366760795 0.04984682827195558 0.0651914803949428 7.5890634002415e-07 6.119811818993303 0.4547745714166005 S(ph)RSPFSTTR ddPTM_PC-9_Lapatinib_30min_R1 2 SRSPFSTTR 9 1 K7EPI8;Q8NG27-2;Q8NG27-3;Q8NG27 K7EPI8 PJA1 E3 ubiquitin-protein ligase Praja-1 1 S(0.907)RS(0.091)PFS(0.002)T(0.001)TR;S(0.991)RS(0.009)PFSTTR 86.882 0.0053412 27319000.0 22841.0 23583.0 28547.8 34681.0 27282.0 20807.0 23453.7 21378.0 23473.0 22273.2 True False 22515.2831514736 23528.395012435198 26200.71008169479 37231.556432424484 25677.326398475732 19917.133113485987 24668.017826164527 22371.29992422595 20829.223558351958 26123.09294282655 0.8618919360257582 0.9006741684045547 1.0029712078519228 1.4252353851785509 0.9829359201329478 0.7624339566940624 0.9442992788087297 0.8563802139810994 0.7973490583193633 1.0 14.67303809990658 -6.531199747950488 24.090310309871224 0.8681908720686593 1.0552584045085809 0.22347177533379725 0.15505241355670318 191.80207950936148 555283.3806199697 0.05438100082026621 0.054479371915415284 2.943067697753323e-07 6.531199747950488 0.18706753243992158 S(ph)RSPGRPPK ddPTM_PC-9_AZD4547_30min_R2 1 SRSPGRPPK 9 2 C9JXK0;A0A494C1L1;Q14739 C9JXK0 LBR Lamin-B receptor 1 S(0.855)RS(0.145)PGRPPK 59.153 0.024103 3361500.0 11460.0 9340.3 11300.0 6454.8 7402.0 4722.4 5711.2 3857.1 8489.1 8940.8 True False 15104.041617192008 12359.369315478363 11150.154616711168 4966.745585665879 6374.360067820385 4427.107581468946 6219.485735939578 3261.0738223404846 8937.816495158866 8627.785313367718 1.7506278921648766 1.4325077486952535 1.2923542035098325 0.5756686571663417 0.7388176497558508 0.5131221304973449 0.7208670023700324 0.3779734548201891 1.0359340399106585 1.0 13.074774562783865 -5.561383819398751 2.3744666341127987 0.6731635468427905 1.6035140597723467 0.7503305247650336 0.20937424430339485 0.12990467648085183 1.4604823339240722 0.056549938638953946 0.1277967385045363 2.7454667007507453e-06 5.561383819398751 0.9303505129295563 S(ph)RSPGRPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRSPGRPPK 9 2 C9JXK0;A0A494C1L1;Q14739 C9JXK0 LBR Lamin-B receptor 1 S(0.924)RS(0.076)PGRPPK 45.972 0.0443 2802200.0 7793.2 11178.0 8007.5 6426.5 14276.0 7929.0 5507.7 5972.7 6705.6 7195.8 True False 9112.434837283829 12287.677967171578 8198.429168612854 6066.444039994118 11478.720281123486 7513.189281793243 4985.970783705107 5815.92295359875 6803.656714251145 8500.341578078542 1.0720080779793377 1.4455510821894693 0.9644823203053056 0.7136706195006114 1.3503834140884243 0.8838691025274729 0.5865612267350979 0.6841987348599478 0.8003980371561817 1.0 13.05330510039462 -6.992723226054617 24.477949777599918 0.7405787687642664 1.099812221928419 0.36754945594663624 0.21172900208001108 145.40060042266853 489101.46293119894 0.07627619171319897 0.06712159696029887 1.0168965500676301e-07 6.992723226054617 0.35923345316415256 S(ph)RSPGSPVGEGTGSPPK ddPTM_PC-9_AZD4547_30min_R2 1 SRSPGSPVGEGTGSPPK 17 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5;A0A0A0MSR2 P35611 ADD1 Alpha-adducin 1 S(0.993)RS(0.006)PGSPVGEGTGSPPK 210.39 4.8281000000000004e-17 9205500.0 14198.0 12626.0 16456.0 26785.0 24663.0 23857.0 21343.0 21665.0 13586.0 18481.0 True False 18712.668663254102 16707.10758511289 16237.782687840609 20610.13207412478 21238.9681643683 22365.218018614403 23242.4856531304 18317.17206217277 14304.128223631282 17833.985815178596 1.049270132721966 0.9368128784140553 0.9104965573102872 1.1556660573646633 1.1909266040960798 1.2540784909439175 1.3032692687996086 1.0270935646131854 0.8020713020561543 1.0 14.122341554366502 -5.765868576187147 24.982908627331888 1.1239451688791289 0.9626551498897511 0.16421946327240344 0.13921942818430594 181.6956194901244 1024863.7427180548 0.04205265499035749 0.06486691820758071 1.7144760543494102e-06 5.765868576187147 -0.16129001898937778 S(ph)RSPGSPVGEGTGSPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRSPGSPVGEGTGSPPK 17 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5;A0A0A0MSR2 P35611 ADD1 Alpha-adducin 1 S(0.683)RS(0.308)PGS(0.009)PVGEGTGSPPK 58.658 0.019563999999999998 6210000.0 33803.0 34173.0 42716.0 43190.0 44493.0 44252.0 37731.0 37407.0 30720.0 34780.0 True False 39525.18026031736 37565.469598510834 43734.511441332106 40770.204323869264 35774.91604567296 41931.34721880619 34156.846531215844 36425.10588599266 31169.22188346981 41085.338681671514 0.962026395025188 0.914327855237301 1.0644797595606146 0.9923297612259229 0.8707465288982131 1.0205914947833226 0.831363392081601 0.886571878309529 0.7586458547894274 1.0 15.326336039032748 -7.268995979883161 24.99999999615174 0.8596929342112202 0.9688813318250145 0.30182315576792373 0.07512520959346407 698.6045731030963 2311229.579106368 0.029975144558892414 0.020656283727709633 5.382747651203099e-08 7.268995979883161 0.10918839761379429 S(ph)RSPGSPVGEGTGSPPK ddPTM_PC-9_Lapatinib_30min_R1 1 SRSPGSPVGEGTGSPPK 17 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5;A0A0A0MSR2 P35611 ADD1 Alpha-adducin 1 S(0.897)RS(0.097)PGS(0.001)PVGEGTGS(0.005)PPK 159.4 0.00014061 16988000.0 33798.0 29657.0 36249.0 31666.0 32220.0 33870.0 26168.0 27098.0 32027.0 24890.0 True False 33316.03432220588 29588.33103862066 33268.74714518647 33994.82327467933 30324.882946957234 32421.459054826286 27522.850998992642 28357.07200611259 28419.782000738636 29192.20333615973 1.1412648075432543 1.0135696404241696 1.1396449511564348 1.1645172131481663 1.0388007577829685 1.1106204859386735 0.9428151305352378 0.9713919733830888 0.9735401495212143 1.0 14.833295484606392 -7.257321437625379 24.99646329946361 0.9695528086874677 1.0991721005614996 0.6627393299069619 0.04521570091408551 216.34768795673983 1313264.7615939574 0.01768901760290855 0.013203999373407235 5.529407055840169e-08 7.257321437625379 0.12961929187403187 S(ph)RSPHEAGFCVYLK ddPTM_PC-9_AZD4547_30min_R2 1 SRSPHEAGFCVYLK 14 1 Q9NTZ6 Q9NTZ6 RBM12 RNA-binding protein 12 1 S(0.5)RS(0.5)PHEAGFCVYLK 86.46700000000001 0.0082777 0.0 18003.0 15780.0 28885.0 35627.0 33604.0 23344.0 19860.0 26562.0 20577.0 19294.0 True False 23727.579514337493 20880.57640528128 28501.966026876267 27413.745581663 28938.664647262412 21884.295989710976 21627.5015260821 22457.453234037977 21664.658211221926 18618.522932636544 1.2744071911711774 1.1214947867147702 1.5308392685068999 1.4723909990523063 1.5542943310790576 1.1754045188702824 1.1616121001828288 1.2061887677820105 1.163607784012006 1.0 14.184451003343796 -6.883052534370531 8.588019912367763 1.1528174245813676 1.3877279521270593 0.4837468424977923 0.1286760758073807 0.2663667463255512 18.882767313666882 0.04920468849247477 0.04340782252664242 1.309023567571314e-07 6.883052534370531 0.23491052754569175 S(ph)RSPIIHSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRSPIIHSPK 10 1 E9PQ01;O94913;E9PKN0 E9PQ01 PCF11 Pre-mRNA cleavage complex 2 protein Pcf11 1 S(0.985)RS(0.009)PIIHS(0.006)PK 68.132 0.030287 0.0 22710.0 24858.0 23520.0 26149.0 26106.0 25983.0 20004.0 21189.0 27767.0 20740.0 True False 26554.35445705431 27325.73795920121 24080.806000096723 24683.956306201846 20990.716703489034 24620.405739542668 18109.07630358172 20632.811201601275 28173.03984499695 24499.997822250327 1.0838512986698416 1.1153363423724312 0.9828901281871584 1.007508510216456 0.8567640232370043 1.0049146093059236 0.7391460372757862 0.8421556341063442 1.1499200958871454 1.0 14.580494000539385 -5.567301792290168 1.4150969348145988 0.919766640899206 1.107726941415477 0.2391470642050325 0.10751498172471517 0.6237885271550832 2.3609546002208983 0.034664876754636524 0.10914261962798359 2.7083089673539217e-06 5.567301792290168 0.18796030051627088 S(ph)RSPLAR ddPTM_PC-9_AZD4547_30min_R2 1 SRSPLAR 7 1 Q8N3Y1 Q8N3Y1 FBXW8 F-box/WD repeat-containing protein 8 1 S(0.96)RS(0.04)PLAR 60.294 0.035684 16349000.0 5730.7 4165.6 6631.9 9195.5 8082.2 6667.4 7393.3 7693.8 5919.0 8031.7 True False 7552.943394035098 5512.0487372521975 6543.956672793515 7075.619544058777 6960.126038927035 6250.486423997553 8051.289377280092 6504.899995935604 6231.866256122005 7750.5126276592155 0.9745088817842767 0.711185053435224 0.8443256578203783 0.9129227812374693 0.898021379139293 0.8064610335181538 1.0388073362460564 0.8392864199358375 0.8040585901224617 1.0 12.920076019684238 -5.64549693917584 5.870953559745325 0.894823471035165 0.8276384505981661 0.06514666076134934 0.09297965708163665 0.5151291012725611 24.344069720147292 0.024510322088836575 0.042900574134436764 2.262054482239306e-06 5.64549693917584 -0.06718502043699892 S(ph)RSPLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRSPLAR 7 1 Q8N3Y1 Q8N3Y1 FBXW8 F-box/WD repeat-containing protein 8 1 S(0.992)RS(0.008)PLAR;S(0.999)RS(0.001)PLAR 76.847 0.014466 18852000.0 7118.1 6807.1 8845.5 7437.1 10938.5 10430.1 7264.200000000001 7891.4 8219.0 7583.1 True False 8323.053741116617 7482.863901443338 9056.410266745555 7020.423398403521 8795.179447679264 9883.127194858329 6576.082387746368 7684.259111629443 8339.187326179645 8957.856002213432 0.929134576293707 0.8353409453773725 1.011001992497733 0.7837169292148497 0.9818397890640381 1.1032915903555793 0.7341134291644629 0.8578234691125544 0.9309356305927536 1.0 13.128937759678836 S(ph)RSPLAR ddPTM_PC-9_Lapatinib_30min_R1 1 SRSPLAR 7 1 Q8N3Y1 Q8N3Y1 FBXW8 F-box/WD repeat-containing protein 8 1 S(0.998)RS(0.002)PLAR 73.616 0.016901 2519200.0 5360.0 3683.0 4213.9 4731.6 4324.6 2466.7 3975.1 4345.0 4622.9 3129.4 True False 5283.565417096386 3674.4722397828464 3867.449408124394 5079.577648154892 4070.2355304907287 2361.204991158548 4180.911227686321 4546.884562202346 4102.220320704864 3670.3126203366087 1.4395409774690593 1.0011333147544952 1.0537111707312021 1.3839632133812727 1.1089615385725489 0.64332530642635 1.1391158356703917 1.2388275965945774 1.1176759979450046 1.0 11.841687235087806 -4.753339130690969 24.727985242222182 1.0821264537374387 1.4395417345478527 0.26557117999662894 0.18098367975450214 399.33002681632433 1218941.565758551 0.04759800179751923 0.5132671607450203 1.7646593001853836e-05 4.753339130690969 0.35741528081041407 S(ph)RSPLELEPEAK ddPTM_PC-9_AZD4547_30min_R2 3 SRSPLELEPEAK 12 1 A0A087WTQ7;A0A087WV56;A0A087WW71;A0A087X0X5;Q92466-3;Q92466-2;Q92466-5;Q92466-4;Q92466 A0A087WTQ7 DDB2 DNA damage-binding protein 2 1 S(0.5)RS(0.5)PLELEPEAK;S(0.925)RS(0.075)PLELEPEAK;S(0.509)RS(0.491)PLELEPEAK 117.48 0.00029661 336409400.0 966858.0 930527.0 2338509.0 2842180.0 2556592.0 2145102.0 1256412.0 2773754.0 1633433.0 2023203.0 True False 1274298.732104276 1231301.6553027357 2307498.8427053625 2186959.312243268 2201653.3307901984 2010968.4328358842 1368230.2340074424 2345134.0538259884 1719772.9336604376 1952371.2787850616 0.6526928284343835 0.6306698263195927 1.1818955071605504 1.1201554417478359 1.1276816836602217 1.0300133251741375 0.7008043238880652 1.2011721742215644 0.8808636719603009 1.0 20.89679600292566 -5.248375101621829 24.629786269170637 1.0324137602904389 0.6416812309880637 0.5448776179091952 0.1420668749108942 477.4825766441847 900182.0476871859 0.0365850661459198 0.09549059062818922 5.644492474809971e-06 5.248375101621829 -0.3907325293023751 S(ph)RSPLELEPEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SRSPLELEPEAK 12 1 A0A087WTQ7;A0A087WV56;A0A087WW71;A0A087X0X5;Q92466-3;Q92466-2;Q92466-5;Q92466-4;Q92466 A0A087WTQ7 DDB2 DNA damage-binding protein 2 1 S(0.544)RS(0.456)PLELEPEAK;S(0.691)RS(0.309)PLELEPEAK;S(0.914)RS(0.086)PLELEPEAK 136.14 2.9486e-05 102203000.0 306944.0 335993.0 383136.0 404193.0 452383.0 395725.0 387775.0 325966.0 367482.0 293803.0 True False 358903.5567796599 369348.1645396204 392271.41529137176 381547.37662138673 363741.7986085383 374972.48436595156 351042.14475211996 317409.7378895261 372855.72904235846 347067.1581567325 1.0341040583781833 1.0641979682007998 1.1302464265841754 1.0993473961863118 1.0480444203950743 1.0804032463268025 1.0114530761611054 0.9145484683001515 1.074304267285296 1.0 18.404855328493923 -7.332954965627421 4.343850213067749 0.9905592185021667 1.0779241582756838 0.41763060828384413 0.04383380754519198 0.20598740904137156 7.509963796727236 0.018811124265527304 0.012500159391296674 4.645634458523411e-08 7.332954965627421 0.08736493977351711 S(ph)RSPLELEPEAK ddPTM_PC-9_Lapatinib_30min_R1 3 SRSPLELEPEAK 12 1 A0A087WTQ7;A0A087WV56;A0A087WW71;A0A087X0X5;Q92466-3;Q92466-2;Q92466-5;Q92466-4;Q92466 A0A087WTQ7 DDB2 DNA damage-binding protein 2 1 S(0.608)RS(0.392)PLELEPEAK;S(0.74)RS(0.26)PLELEPEAK;S(0.5)RS(0.5)PLELEPEAK 112.12 0.00046778 727930000.0 1251910.0 955885.0 2697330.0 1080662.0 1972130.0 2028920.0 1244970.0 1501870.0 2597840.0 1239210.0 True False 1234057.5338278203 953671.7070118978 2475565.939394906 1160137.4884627548 1856133.190756762 1942147.8212435232 1309428.4549150064 1571652.3630459898 2305243.902732035 1453405.7973564703 0.8490798207027852 0.6561634119985522 1.703286132405412 0.7982199400696439 1.2770921886597626 1.33627361661554 0.9009379605452673 1.0813582592725257 1.5860979135523832 1.0 20.471006135403805 -5.2029344124622146 24.999986047114152 1.1944188221550354 0.7526209239864791 0.3071909456147368 0.27415527582583515 315.98337025054417 135022.59782288136 0.0661798849693216 0.1750954541883065 6.267085035999012e-06 5.2029344124622146 -0.4417978981685563 S(ph)RSPLGFYVHLK ddPTM_PC-9_AZD4547_30min_R2 1 SRSPLGFYVHLK 12 1 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 1 S(0.5)RS(0.5)PLGFYVHLK 75.02 0.0085125 6928800.0 20021.0 20445.0 28200.0 34337.0 32403.0 30267.0 25381.0 32089.0 22992.0 27715.0 True False 26387.26153732993 27053.446426234193 27826.04957444734 26421.13515136167 27904.40276649339 28374.39970530253 27639.859830487883 27130.382381863 24207.31018090169 26744.706285789456 0.9866349346057522 1.0115439719975083 1.0404320495092685 0.9879014885798273 1.0433617205704788 1.0609351773056859 1.033470307549201 1.014420651771318 0.9051252955342424 1.0 14.706965739436102 -8.110438191856414 7.299637030916773 0.9531663168551573 1.0244547354201634 0.45323148300556715 0.030767285110675568 0.22364958269837987 13.052432793910944 0.02060823747298383 0.007710485367659096 7.754642984301742e-09 8.110438191856414 0.07128841856500612 S(ph)RSPLGFYVHLK ddPTM_PC-9_Lapatinib_30min_R1 1 SRSPLGFYVHLK 12 1 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 1 S(0.492)RS(0.492)PLGFY(0.016)VHLK 56.46 0.036081 5151200.0 11940.0 13231.0 12764.0 14161.0 16375.0 14732.0 11722.0 10747.0 16632.0 11178.0 True False 11769.733410472169 13200.364432410222 11714.593190464839 15202.447179711182 15411.85469448867 14101.946701969326 12328.907803813507 11246.34485385239 14758.729017275578 13110.102406251242 0.8977606006235351 1.0068849215179234 0.893554667038986 1.1595978969975287 1.1755708854829303 1.0756549617221256 0.9404127764810409 0.8578380629955901 1.1257523823946811 1.0 13.678391334400787 -5.733535619824622 24.99975322060223 1.0439149919169701 0.9401485472664813 0.22644127154762195 0.09700926787520459 405.61787452544615 363401.2740814433 0.029003021520621723 0.05022153202633445 1.8469893029247603e-06 5.733535619824622 -0.10376644465048879 S(ph)RSPLLVTVVESDPRPQGQPR ddPTM_PC-9_AZD4547_30min_R2 2 SRSPLLVTVVESDPRPQGQPR 21 2 A0A2R8YH03;Q5VWN6;Q5VWN6-2 A0A2R8YH03 FAM208B Protein FAM208B 1 S(0.5)RS(0.5)PLLVTVVESDPRPQGQPR;S(0.5)RS(0.5)PLLVTVVESDPRPQGQPR 105.38 2.7026e-05 30282000.0 66752.0 86194.0 116628.0 134514.0 107532.0 99250.0 79336.0 113769.0 78819.0 103300.0 True False 87977.74747214667 114054.52488446224 115081.4365166185 103503.87552058329 92603.03793743048 93043.88181026468 86396.75030580309 96188.61520153847 82985.21142782236 99683.49844207286 0.8825708251328225 1.144166553812721 1.1544682752431041 1.038325070229457 0.9289705857508912 0.9333930215574594 0.8667106557863151 0.9649402027902813 0.8324869484395749 1.0 16.60506708090155 -6.224332948668018 3.589397994663884 0.9157717072890652 1.072205611182568 0.3880810332352831 0.0820397635258607 0.2255605978096166 6.133953223307327 0.02505752972462989 0.031913593195168455 5.965777492819414e-07 6.224332948668018 0.15643390389350276 S(ph)RSPLLVTVVESDPRPQGQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SRSPLLVTVVESDPRPQGQPR 21 2 A0A2R8YH03;Q5VWN6;Q5VWN6-2 A0A2R8YH03 FAM208B Protein FAM208B 1 S(0.5)RS(0.5)PLLVTVVESDPRPQGQPR;S(0.888)RS(0.112)PLLVTVVESDPRPQGQPR;S(0.5)RS(0.5)PLLVTVVESDPRPQGQPR 110.57 1.0938e-05 30585100.0 44369.9 47088.0 50360.0 63635.0 60159.0 60924.0 50645.0 54213.0 50755.6 42250.0 True False 51880.847724529005 51762.58544624934 51560.773391363524 60069.73725745357 48371.27580499494 57729.03818942758 45847.538961952385 52789.96619342159 51497.80462983858 49909.590549183995 1.0394965607542384 1.037127030630301 1.0330834780251774 1.2035710290641863 0.9691779730656556 1.1566722458389598 0.9186118030115151 1.0577118668484986 1.0318218214811732 1.0 15.607029447783068 -7.260090528698909 24.998802861729605 1.006845699629818 1.0709247448468124 0.19419439797839044 0.07064369623732582 233.8225053944161 4333619.197824859 0.02695693811600013 0.0197421017815214 5.494263339828917e-08 7.260090528698909 0.06407904521699437 S(ph)RSPLLVTVVESDPRPQGQPR ddPTM_PC-9_Lapatinib_30min_R1 1 SRSPLLVTVVESDPRPQGQPR 21 2 A0A2R8YH03;Q5VWN6;Q5VWN6-2 A0A2R8YH03 FAM208B Protein FAM208B 1 S(0.5)RS(0.5)PLLVTVVESDPRPQGQPR 103.28 3.6709000000000004e-05 12623000.0 12237.0 8346.4 15131.0 12341.0 12748.0 13333.0 11071.0 13979.0 14258.0 9204.3 True False 12062.498136009042 8327.074423601283 13886.987587349066 13248.598308369155 11998.187703532307 12762.778670741043 11644.20220918096 14628.515372848478 12652.113896603842 10795.250991041172 1.117389317397024 0.7713645963870415 1.286397842798994 1.2272617208589205 1.1114320281658514 1.1822586321830493 1.0786411746094946 1.3550880275955122 1.1720073861278126 1.0 13.398109166154045 -5.272175483697451 24.958472953377584 1.185497929460909 0.9443769454091626 0.36040238762502463 0.12331200092713218 593.1396962060074 1378887.067955317 0.030411472740069546 0.06432648760912381 5.343484036697182e-06 5.272175483697451 -0.2411209840517463 S(ph)RSPQAFR ddPTM_PC-9_AZD4547_30min_R2 1 SRSPQAFR 8 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;H3BSK8 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 S(0.941)RS(0.059)PQAFR 75.189 0.012609 32638000.0 4893.0 1908.7 5034.4 6258.0 4086.0 4452.4 1719.0 5472.2 3099.9 1893.6 True False 6448.872219277533 2525.6499483371567 4967.640566581478 4815.314785136191 3518.7294294939356 4173.990724151352 1871.9876698557464 4626.597228646287 3263.7543854287223 1827.3056403669825 3.529169984930594 1.3821715932699272 2.718560298201572 2.635199431754131 1.9256381372452067 2.2842323867139593 1.0244524115187377 2.5319230272375863 1.7861020692593355 1.0 10.835502248109018 -6.65509600017627 1.5887133628581545 1.728526696234526 2.485054732201552 0.26874190842597245 0.6590523273461585 0.6166892039197598 3.2188006622844885 0.2651323308353461 0.2624129731800599 2.2126055622388287e-07 6.65509600017627 0.7565280359670261 S(ph)RSPQAFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRSPQAFR 8 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;H3BSK8 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 S(0.995)RS(0.005)PQAFR;S(0.997)RS(0.003)PQAFR 64.567 0.025553 44433000.0 7711.0 5149.1 7340.5 5291.9 7204.4 6589.6 5338.7 7358.1 4542.0 3019.1 True False 9016.320000807824 5660.26861878361 7515.525359001274 4995.41199957128 5792.749537218131 6244.02977567218 4832.97968715915 7164.957671551382 4608.418157380209 3566.438930817552 2.5281016093947164 1.5870925392478483 2.1072911957245974 1.4006722381830208 1.6242390938375697 1.750774342921619 1.3551275602667512 2.008994913564642 1.2921623632915535 1.0 11.80026855474354 -1.5228787452803376 0.08646627685885598 0.6350279470116968 4.6201916411025525 0.48484492892062636 0.3062928089991951 160.17566855043304 1.004712825263272 6.373366766814517 75.83512348401771 0.029999999999999995 1.5228787452803376 3.985163694090856 S(ph)RSPQAFR ddPTM_PC-9_Lapatinib_30min_R1 2 SRSPQAFR 8 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;H3BSK8 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 S(0.999)RS(0.001)PQAFR;S(0.966)RS(0.034)PQAFR 92.051 0.0038996 57561000.0 17932.5 11449.8 15002.5 9352.2 11302.8 10912.699999999999 12441.8 11907.1 15209.2 10462.7 True False 17676.77926158225 11423.28869157361 13769.052361324719 10039.991986024641 10637.991526159787 10445.989259746175 13085.975525805055 12460.347335005648 13496.179736023798 12271.16375432858 1.4405136803220373 0.9309050812351937 1.122065733697651 0.8181776551130363 0.8669097519301948 0.8512631294698039 1.066400529549535 1.015416922507479 1.0998288350005192 1.0 13.582984455199298 -4.758512659622336 24.999571839646354 0.9704105002378348 1.4405143157010603 0.6579487289782515 0.10075101473819142 52.1261280406733 445172.3863068765 0.026376863677650655 0.1796326598742112 1.7437625262955228e-05 4.758512659622336 0.47010381546322544 S(ph)RSPQWR ddPTM_PC-9_AZD4547_30min_R2 2 SRSPQWR 7 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.997)RS(0.003)PQWR;S(0.985)RS(0.015)PQWR 64.42 0.028047000000000002 36302000.0 8904.9 8949.8 10358.7 15341.8 13058.0 13253.7 10436.7 12507.9 10594.400000000001 15018.5 True False 11736.47296657356 11842.647827122066 10221.336869745657 11804.985038447168 11245.122097486983 12424.944043815636 11365.546081433078 10575.091457948345 11154.39835510373 14492.706886275619 0.8098192462367281 0.817145335240091 0.7052745184148528 0.8145465944409817 0.7759159269367374 0.8573239037616828 0.7842252086251799 0.7296836637165968 0.7696559685248849 1.0 13.823039460067754 -11.07998069179941 6.259826289044071 1.000363806603403 0.784555477906745 0.7043444485868562 0.041818895839882825 0.00021706833890048916 1.5358062462640997e-05 0.04139495627162102 0.010023102918799607 8.318007511229374e-12 11.07998069179941 -0.2158083286966581 S(ph)RSPQWR ddPTM_PC-9_Lapatinib_30min_R1 2 SRSPQWR 7 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.942)RS(0.058)PQWR;S(0.91)RS(0.09)PQWR 62.54600000000001 0.031389999999999994 36000000.0 10587.3 8926.7 11947.599999999999 9818.4 12412.4 11278.8 11817.8 11062.1 12290.3 9417.1 True False 10436.32316052697 8906.030774604817 10965.314447069706 10540.477889222242 11682.32703571732 10796.432016166958 12429.667859060504 11576.085550181495 10906.036991403442 11044.833187502998 0.9449054579054625 0.8063526739979928 0.9928003674583998 0.9543356346158832 1.057718739377217 0.9775097398829798 1.125383031870904 1.0480996275506993 0.9874333823115952 1.0 13.431084009072919 -5.697251824641577 1.4171491290034548 1.0368056577728069 0.8771560540940013 0.490000246537893 0.05694777045774118 0.33714320751555377 1.3397086098165447 0.018044883673219825 0.046685262697680384 2.0079281825177263e-06 5.697251824641577 -0.15964960367880554 S(ph)RSPSSPELNNK ddPTM_PC-9_Lapatinib_30min_R1 1 SRSPSSPELNNK 12 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.862)RS(0.13)PS(0.006)S(0.002)PELNNK 101.45 0.012381999999999999 0.0 15540.0 14609.0 14348.0 12358.0 12283.0 12434.0 12087.0 9545.9 15846.0 10978.0 True False 15318.396750313024 14575.17375807429 13168.362824881664 13266.848545079489 11560.538089307136 11902.226805069678 12712.805717854792 9989.437363021258 14061.256614222517 12875.532672734491 1.1897291661378482 1.1320054966688093 1.0227431485430716 1.0303922084073194 0.897868723815053 0.9244065552545327 0.9873615360998389 0.7758465313186699 1.0920912533583127 1.0 13.652344498712552 -5.300786732883585 1.053701890638273 0.9372796185715162 1.2230897473587905 0.5186244258090686 0.07899076420753426 0.6556323480211947 1.026649334003695 0.02583165297837016 0.17366343289350436 5.0028014507787195e-06 5.300786732883585 0.2858101287872743 S(ph)RSPVDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRSPVDLR 8 1 Q13523 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 S(0.61)RS(0.39)PVDLR;S(0.997)RS(0.003)PVDLR 95.741 0.0029884 14240000.0 29506.0 24002.0 32666.0 25142.0 34835.0 31079.0 26243.0 28962.0 25581.4 20730.5 True False 34500.78302993589 26384.75993630812 33444.881326494855 23733.375251463793 28009.331815139834 29449.162528547382 23757.073057133322 28201.778187775537 25955.47957974594 24488.775547452307 1.4088406732742986 1.0774225883683703 1.3657228905417567 0.9691532026774976 1.1437620374634774 1.2025575746522421 0.9701209033950614 1.1516205917739122 1.0598929100988155 1.0 14.579833019691401 -1.5228787452803376 0.44538819422458226 1.0697498877081917 7.167526171396281 0.3842997269992662 0.11505731699600834 95.78391222135859 1.1656584313840563 0.06893038050906522 529.5775386791662 0.029999999999999995 1.5228787452803376 6.0977762836880895 S(ph)RSPVDLR ddPTM_PC-9_Lapatinib_30min_R1 1 SRSPVDLR 8 1 Q13523 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 S(0.991)RS(0.009)PVDLR 84.743 0.0064862999999999995 9249900.0 14262.0 9846.5 13946.0 15117.0 15702.0 13327.0 11961.0 13338.0 14529.0 9553.3 True False 14058.621264669522 9823.70103421716 12799.41371311679 16228.754608833693 14778.439231319768 12757.035276754354 12580.282054377514 13957.732172762922 12892.591022847335 11204.575176027902 1.2547214904450665 0.8767580099988876 1.1423381531234698 1.448404277170185 1.3189647085360379 1.1385559092010848 1.1227808155808465 1.2457172140381885 1.150654158707501 1.0 13.451800329329785 -10.622628683348875 14.592549081940938 1.0000002670526877 1.1879471552173344 0.1382881827067176 0.141349030050456 0.0 0.0 0.14674430474636127 0.03559072167218086 2.384357195351154e-11 10.622628683348875 0.18794688816464666 S(ph)RSPVEQR ddPTM_PC-9_Lapatinib_30min_R1 1 SRSPVEQR 8 1 P35612-2;P35612-8;P35612-9 P35612-2 ADD2 Beta-adducin 1 S(0.984)RS(0.016)PVEQR 58.782 0.036004 958630.0 2264.1 2195.6 2871.9 1074.5 2658.5 2452.2 3140.4 2591.2 1098.5 1039.8 True False 2231.81351881491 2190.516223097261 2635.7834678545896 1153.5223144269237 2502.1322568121013 2347.325122357398 3302.9945459047863 2711.5966116406726 974.7753622821799 1219.52804455359 1.830063300948416 1.7961999585660227 2.161314354045398 0.9458760047204754 2.051721785314097 1.9247815848438645 2.7084203275652032 2.223480324007847 0.7993054088715097 1.0 10.252107219731956 S(ph)RSQPCDLDAR ddPTM_PC-9_AZD4547_30min_R2 1 SRSQPCDLDAR 11 1 Q9NYF3 Q9NYF3 FAM53C Protein FAM53C 1 S(0.677)RS(0.323)QPCDLDAR 111.88 0.0084821 4336000.0 10849.0 10759.0 16870.0 15194.0 16123.0 12750.0 10289.0 15988.0 10219.0 12812.0 True False 14298.756326781511 14236.636346287778 16646.292777337818 11691.258044959943 13884.599753238052 11952.740484442033 11204.701067565886 13517.421967690667 10759.155477498016 12363.455779669293 1.1565339482424213 1.151509464667539 1.3464109933333772 0.9456302714476703 1.1230355008079664 0.9667798953183746 0.9062758234628148 1.093336863785203 0.8702385214327033 1.0 13.593794435036449 -5.776315147635828 24.99843867955339 0.991888254614119 1.211487290055155 0.5925436270367056 0.08790750363946223 159.06519618922957 267305.6084207824 0.02412362718054375 0.035945021573156384 1.6737278874968134e-06 5.776315147635828 0.21959903544103598 S(ph)RSQPCDLDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRSQPCDLDAR 11 1 Q9NYF3 Q9NYF3 FAM53C Protein FAM53C 1 S(0.5)RS(0.5)QPCDLDAR;S(0.5)RS(0.5)QPCDLDAR 59.84 0.031198000000000004 30476000.0 62438.0 67865.0 69757.0 82340.0 91705.0 69778.0 76226.0 71705.0 66647.0 53504.0 True False 73007.52019328745 74602.1886958398 71420.27143489564 77726.75674988171 73736.06355985074 66118.71884285136 69005.32145155084 69822.81972772768 67621.58629126352 63203.85166256907 1.1551118843683439 1.1803424432758283 1.1299987193216032 1.2297787983689208 1.1666387667876752 1.0461185054962172 1.0917898140125146 1.104724125050096 1.0698966045974496 1.0 15.947724858919681 -6.740014790843855 13.047130552512387 1.07088369721306 1.1736720588611718 0.7010615226865432 0.03565776642724873 0.6614962666668681 401.48152183027315 0.011538725884321232 0.011434952486522614 1.8196388857918476e-07 6.740014790843855 0.10278836164811178 S(ph)RSQPCDLDAR ddPTM_PC-9_Lapatinib_30min_R1 1 SRSQPCDLDAR 11 1 Q9NYF3 Q9NYF3 FAM53C Protein FAM53C 1 S(0.841)RS(0.159)QPCDLDAR 120.6 0.0041034 13742000.0 14016.0 18219.0 18288.0 14407.0 13853.0 17627.0 15458.0 15320.0 17038.0 17494.0 True False 13816.129269780396 18176.81502487203 16784.431233721476 15466.538840343126 13038.193776045904 16873.134300543945 16258.3396034251 16031.82312840965 15119.001021906044 20517.814590710248 0.6733723617931443 0.8859040491135863 0.8180418611113136 0.7538102448467312 0.6354572373389681 0.8223650830816803 0.7924011366583997 0.7813611463117666 0.7368719000293239 1.0 14.32458945323079 -10.526966117501296 6.067215216480452 1.000000208372211 0.77023811244281 0.5050273918627987 0.0692300417396764 1.970479626468344e-07 3.2335282925419185e-08 0.06769022407087665 0.016417275881186594 2.971897882250644e-11 10.526966117501296 -0.229762095929401 S(ph)RSQRS(ph)DS(ph)Y(ph)HR ddPTM_PC-9_AZD4547_30min_R2 1 SRSQRSDSYHR 11 2 P30414;A0A087WYW3 P30414 NKTR NK-tumor recognition protein;Putative peptidyl-prolyl cis-trans isomerase 4 S(0.96)RS(0.276)QRS(0.772)DS(0.995)Y(0.998)HR 50.034 0.041103 0.0 3331.2 2385.4 3222.8 4543.9 3829.5 3686.2 2406.7 3258.9 2934.0 4236.5 True False 4390.452306735603 3156.4339009605774 3180.063566259888 3496.3740575551856 3297.84002698165 3455.7013312745275 2620.8916376043194 2755.3118870719964 3089.0852501202835 4088.181424490239 1.0739377368221996 0.7720875306687637 0.777867524961032 0.8552394560109703 0.8066765352501113 0.8452906005034803 0.6410898552358454 0.6739700617409757 0.7556135428861174 1.0 11.997243505987658 -7.15868482480019 15.422548111573628 0.7405024256900026 0.8457235261122469 0.09279228657873861 0.12066501093850512 3.4720474174451432 513.1447437322715 0.04439991925416401 0.034392316670129146 6.939292200554059e-08 7.15868482480019 0.1052211004222443 S(ph)RSSDIVSSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRSSDIVSSVR 11 1 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 S(0.813)RS(0.143)S(0.045)DIVSSVR 74.649 0.010665000000000001 66520000.0 33414.0 37556.0 51018.0 42701.0 55064.0 42916.0 52095.0 48802.0 38212.0 37640.0 True False 39070.33024341754 41284.31148104272 52234.46260684244 40308.60140850987 44274.6044802314 40665.409410699795 47160.18446486149 47520.99920999318 38770.77820999833 44463.83404192397 0.8786990839921495 0.9284919389118953 1.1747628996094155 0.9065480356575589 0.9957441915262155 0.914572714812611 1.0606414287259887 1.0687562202842578 0.8719621023558657 1.0 15.440344734454698 -7.2653212222913215 24.818346470862046 1.0060696147001669 0.9728183498548342 0.027287167209664398 0.09211087439874613 1488.6230045249868 9517344.198741937 0.03800168892242217 0.026586687620320015 5.4284866947699686e-08 7.2653212222913215 -0.033251264845332695 S(ph)RSSDIVSSVR ddPTM_PC-9_Lapatinib_30min_R1 1 SRSSDIVSSVR 11 1 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 S(0.82)RS(0.151)S(0.03)DIVSSVR 77.633 0.0090995 65652000.0 124500.0 125040.0 102850.0 85770.0 125720.0 109170.0 116700.0 103640.0 118650.0 128740.0 True False 122724.60716949595 124750.47756243458 94394.07001248126 92077.81192033246 118325.39677502983 104501.05358769953 122742.15498251466 108455.49275642163 105286.38756010974 150992.53746473257 0.8127859113445314 0.8262029346422013 0.6251571872187984 0.6098169715297297 0.783650627784616 0.6920941613562055 0.8129021277702789 0.7182837945335786 0.6972953056352309 1.0 17.204117723135063 -11.07015338182045 2.931859023703757 1.012707590154855 0.7294904368977763 0.5470206474268619 0.07345069290814711 56626004.79174249 62278016.49537275 5692516.516382667 0.01987465630319834 8.508374908627552e-12 11.07015338182045 -0.28321715325707875 S(ph)RSSPATADKR ddPTM_PC-9_Lapatinib_30min_R1 1 SRSSPATADKR 11 2 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 S(0.483)RS(0.483)S(0.035)PATADKR 49.243 0.037509 2002900.0 4125.3 4290.3 4084.9 3484.8 4116.8 3774.6 4414.3 4420.1 5847.0 5655.5 True False 4066.472465512634 4280.366073945249 3749.055290169997 3741.0838169520184 3874.6579179402092 3613.1691570223593 4642.850854664219 4625.473982368374 5188.449288360411 6633.045639519941 0.613062639172032 0.6453093053427318 0.5652087282247813 0.564006946471542 0.5841446190050086 0.5447224930121027 0.6999576223329348 0.6973378797229469 0.782212209945825 1.0 12.695455737219511 -8.50620025367001 0.8143699341022184 0.9985453446526078 0.5868150620176439 0.9238245882631653 0.03622506769537414 0.17402980938808674 0.25885397769438884 0.037124398294023156 0.013594050925146364 3.1174517921371747e-09 8.50620025367001 -0.4117302826349639 S(ph)RSTCGDSEVEEESPGKR ddPTM_PC-9_Lapatinib_30min_R1 1 SRSTCGDSEVEEESPGKR 18 2 O95696-2;O95696 O95696-2 BRD1 Bromodomain-containing protein 1 1 S(0.531)RS(0.376)T(0.093)CGDSEVEEESPGKR 86.557 0.007829899999999999 0.0 1801.9 1454.7 4691.1 3253.3 3595.7 3208.3 3613.4 3170.8 4570.8 3002.0 True False 1776.2045755720094 1451.331731526502 4305.415866169667 3492.558534690655 3384.2079954181927 3071.0884879125833 3800.4841714980125 3318.1269435745003 4055.988371342183 3520.891700086441 0.5044757768403959 0.41220572944372885 1.222819737983979 0.99195284382218 0.9611792363096847 0.8722473593371775 1.0794095630390186 0.9424109646692733 1.1519776002319542 1.0 11.781725136358682 -5.251338671792993 24.99879503973581 1.0183282821414765 0.4583406702668517 0.8394680259162219 0.09953262875553814 246.7483592809562 610688.0890003748 0.025037819127390365 0.06463136394716815 5.606106297988185e-06 5.251338671792993 -0.5599876118746248 S(ph)RSTTAHSWQR ddPTM_PC-9_AZD4547_30min_R2 1 SRSTTAHSWQR 11 1 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 S(0.845)RS(0.148)T(0.006)T(0.001)AHSWQR 74.649 0.010665000000000001 3845500.0 2890.4 1360.1 4187.7 6246.2 4535.6 5103.3 4508.4 4912.9 2649.3 4853.8 True False 3809.4870759451805 1799.725726794871 4132.168361805427 4806.235092828006 3905.9102301548432 4784.189844255143 4909.6388660719285 4153.724192210876 2789.336589346856 4683.869939381739 0.8133204220542523 0.38423904807067105 0.882212447246318 1.0261247974495251 0.8339066371835285 1.0214181662112176 1.0482013654546503 0.886814588357071 0.5955196505125508 1.0 12.19348530063484 -5.401053594053959 7.521220795606831 0.9203843421077977 0.6006128618190628 0.3860391523610004 0.15824582880469015 0.24378446454419983 13.905317118495553 0.04065895905926017 0.08508518495611626 3.971425371222679e-06 5.401053594053959 -0.3197714802887349 S(ph)RSTTAHSWQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRSTTAHSWQR 11 1 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 S(0.713)RS(0.273)T(0.01)T(0.004)AHSWQR 55.176 0.040552 945520.0 6027.8 4607.7 5184.0 5851.9 7655.2 7626.3 5481.3 9066.0 7568.3 5928.1 True False 7048.187485523203 5065.122004771558 5307.6062204294785 5524.037015115775 6155.218513313003 7226.3634026661375 4962.071582824558 8828.027106221023 7678.972069683099 7002.817603186221 1.0064788039483334 0.7232977198302254 0.7579243843241845 0.788830629060278 0.8789631348548094 1.0319222650291797 0.7085821542127356 1.2606393035575205 1.0965546305517415 1.0 12.773719795900242 -7.7621322521781115 24.999999044194414 1.1339477352531178 0.8411128977282565 0.5306800937209981 0.1190279273929266 13.66852898159238 493111.0339138592 0.05991099680100928 0.03147283431804801 1.7292896724593e-08 7.7621322521781115 -0.2928348375248613 S(ph)RSTTAHSWQR ddPTM_PC-9_Lapatinib_30min_R1 1 SRSTTAHSWQR 11 1 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 S(0.61)RS(0.347)T(0.035)T(0.008)AHSWQR 56.551 0.037794 2289300.0 3100.2 3249.8 4546.5 2877.4 3024.9 3188.2 2507.9 2595.0 4321.3 3821.3 True False 3055.990579492948 3242.2752877671187 4172.704319997527 3089.013594725015 2846.981329182217 3051.8481180571935 2637.7467907510563 2715.573173513255 3834.5896886936616 4481.806613437811 0.6818657838404193 0.7234304304977812 0.931031764620655 0.6892340212679454 0.635230739462543 0.6809414999984225 0.5885454278286559 0.6059103856402785 0.8555901714269425 1.0 12.129864683654652 -8.510825098099986 4.615547404977907 0.9995270669496653 0.6960226851236541 0.5528472903298147 0.0894807081554808 0.1319747940135239 8.89181915285128 0.09512403651792183 0.024803308712053395 3.0844298818277686e-09 8.510825098099986 -0.30350438182601125 S(ph)RSTTELDDYSTNK ddPTM_PC-9_AZD4547_30min_R2 1 SRSTTELDDYSTNK 14 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.571)RS(0.184)T(0.184)T(0.061)ELDDYSTNK 131.56 7.7204e-05 20881000.0 14091.0 20874.0 36590.0 36335.0 31797.0 35873.0 37502.0 36951.0 42875.0 30988.0 True False 18571.64488899238 27621.112286681953 36104.792692518706 27958.52712015397 27382.53540617195 33629.855639089335 40839.6053489995 31241.07199950825 45141.284968952714 29903.119552013122 0.6210604501209008 0.9236866487671337 1.2073921795924492 0.9349702485562835 0.9157083212854465 1.1246270002229692 1.3657305980388965 1.044742905340291 1.5095844729655885 1.0 14.868008376596817 -6.9125938692227225 3.972888396883974 1.235715974581675 0.9380539352158945 0.3736892898178207 0.18940839942952736 0.25586395707412407 7.7136327832538 0.06899416726536026 0.05995727267141265 1.222942761342651e-07 6.9125938692227225 -0.2976620393657805 S(ph)RSTTELDDYSTNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRSTTELDDYSTNK 14 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.619)RS(0.353)T(0.021)T(0.006)ELDDYSTNK;S(0.719)RS(0.275)T(0.006)TELDDYSTNK 218.12 7.218899999999999e-15 35697000.0 41750.0 49005.0 65776.0 83220.0 91701.0 81500.0 92057.0 98926.0 74049.0 72789.0 True False 48817.45039991268 53869.89253723773 67344.34929686898 78557.45320288015 73732.84733113651 77225.99652744974 83336.69452503625 96329.29732076125 75131.82653805509 85985.06950259299 0.5677433382599119 0.6265028667054018 0.7832098024278288 0.9136173716823145 0.8575075621577883 0.898132629003933 0.969199594849698 1.1203026046034228 0.8737775868843066 1.0 16.391798550706262 -4.629688332343357 0.48481858463681193 1.0015388541271137 0.14690608196353278 0.825879572120093 0.0659283192517694 2.084516341259898 0.33925567740260193 0.04328705660043019 1.0531696630486145 2.3459117345287455e-05 4.629688332343357 -0.8546327721635809 S(ph)RSWEDSPER ddPTM_PC-9_AZD4547_30min_R2 1 SRSWEDSPER 10 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IU26;B1AN86 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(0.934)RS(0.066)WEDSPER 73.84100000000001 0.012694 76153000.0 27534.0 23801.0 32062.0 39017.0 44641.0 29935.0 27831.0 30604.0 15320.0 30570.0 True False 36289.23925722207 31494.207796077288 31636.83693106137 30022.23345664091 38443.36770975005 28063.159717786086 30307.90508420898 25874.85500995779 16129.783923600116 29499.753604783815 1.2301539783483901 1.0676091813516044 1.072444107666411 1.0177113293506415 1.3031758917306988 0.9513014953872441 1.027395194219321 0.8771210551996546 0.5467769032818104 1.0 14.848415284036097 -7.6867623142809505 1.872177353175787 0.763220217233036 1.1091514221797656 0.4858389170439573 0.1393688236912373 0.28151895916739134 1.932880948070651 0.09264913611638416 0.04011855712391249 2.0570160755791494e-08 7.6867623142809505 0.3459312049467296 S(ph)RSWPASPR ddPTM_PC-9_AZD4547_30min_R2 2 SRSWPASPR 9 1 Q86YD1 Q86YD1 PTOV1 Prostate tumor-overexpressed gene 1 protein 1 S(0.994)RS(0.006)WPASPR;S(0.976)RS(0.024)WPASPR 122.18 0.00074173 28477700.0 14966.3 13692.599999999999 18613.8 25799.0 19655.5 18133.9 19129.0 18743.8 13451.5 18402.0 True False 19725.272081621355 18118.46517661307 18366.968849959136 19851.439140576647 16926.67310362654 16999.9843663391 20831.443942216738 15847.376399674762 14162.518828218483 17757.75158113287 1.1107978389887445 1.0203130218277998 1.0343071174322285 1.1179027395376036 0.9531991156814398 0.9573275247526901 1.1730901768188706 0.892420210254105 0.7975400919148894 1.0 14.11616130424994 -7.878804195021573 9.704960061467522 0.8811313938725149 1.0454273293136773 0.43867358951440205 0.0799867788502024 0.2564604924465663 20.497677715490088 0.04251362447301956 0.020395111139005648 1.3218914847091968e-08 7.878804195021573 0.1642959354411624 S(ph)RSWPASPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SRSWPASPR 9 1 Q86YD1 Q86YD1 PTOV1 Prostate tumor-overexpressed gene 1 protein 1 S(0.998)RS(0.002)WPASPR;S(0.998)RS(0.002)WPASPR;S(0.997)RS(0.003)WPASPR;S(0.642)RS(0.358)WPASPR 87.713 0.0050381 42379600.0 35239.5 33111.2 40623.1 43343.9 45981.8 42079.3 38485.7 39373.9 40643.8 33308.3 True False 41204.85133814909 36398.261111702595 41591.70876796466 40915.4818058198 36971.996373113194 39872.58743162597 34840.055883660985 38340.376845095496 41238.13868448475 39346.831121642295 1.047221597357171 0.9250620716869402 1.0570535817581403 1.03986726858201 0.9396435575412108 1.0133621004537388 0.8854602744488258 0.9744209572192661 1.04806759550713 1.0 15.263959829534217 -6.255482957651116 24.736339216975257 0.9728053394630003 1.0135520848551567 0.11768483037192667 0.05322524899495527 971.8682001297228 4036055.0894563324 0.015936205590287973 0.019987423063946783 5.55286406940516e-07 6.255482957651116 0.04074674539215639 S(ph)RSWPASPR ddPTM_PC-9_Lapatinib_30min_R1 3 SRSWPASPR 9 1 Q86YD1 Q86YD1 PTOV1 Prostate tumor-overexpressed gene 1 protein 1 S(0.993)RS(0.007)WPASPR;S(0.969)RS(0.031)WPASPR;S(0.989)RS(0.011)WPASPR 88.155 0.0048771 45509000.0 28124.8 25242.699999999997 29736.7 25198.699999999997 20721.5 28958.7 23859.2 23055.8 26668.600000000002 15695.000000000002 True False 27723.735194543347 25184.25207905687 27291.863312981503 27051.89645839898 19502.70211003646 27720.2039070268 25094.512632037804 24127.056637335998 23664.901435192125 18407.859837727065 1.506081393434087 1.3681249369055675 1.4826201173613132 1.4695840090522576 1.0594768909564114 1.5058895575798554 1.3632498755018978 1.3106931957341066 1.2855867897630722 1.0 14.16803428320747 -13.676127755033832 0.14158017391155311 1.6623700100479522e-14 1.5117407038544155 0.5103354474586684 0.11946084758965878 89.92379178624851 0.9688600423254261 26.303288786488864 0.7448035905945243 2.1080079526863637e-14 13.676127755033832 1.5117407038543988 S(ph)RSWTSPK ddPTM_PC-9_Lapatinib_30min_R1 1 SRSWTSPK 8 1 O75494-2;O75494 O75494-2 SRSF10 Serine/arginine-rich splicing factor 10 1 S(0.994)RS(0.004)WTS(0.001)PK 54.25899999999999 0.044387 4264700.0 20183.0 16616.0 20719.0 13298.0 15521.0 19074.0 14113.0 15538.0 19855.0 15749.0 True False 19895.18671889111 16577.52667288399 19015.56379765285 14275.979280827563 14608.085295460067 18258.249483665688 14843.702084560653 16259.952204257786 17618.72081758096 18471.193665776584 1.0770926383470765 0.897479988182833 1.0294713022734894 0.7728780034004022 0.7908576759998959 0.9884715527342752 0.8036135808625652 0.880287029548297 0.9538485241603479 1.0 14.17298948030681 S(ph)RT(ph)GSESSQTGTSTTSSR ddPTM_PC-9_AZD4547_30min_R2 1 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 S(0.977)RT(0.89)GS(0.125)ES(0.008)SQTGTSTTSSR 130.95 0.00014983 25681000.0 10182.0 7480.0 14825.0 21199.0 15601.0 14651.0 12485.0 16333.0 12293.0 13876.0 True False 13419.664201243362 9897.763720627623 14628.410813517085 16311.898071285097 13435.07044286218 13734.870653926304 13596.140813350188 13809.110145001969 12942.782883343101 13390.205463525686 1.0022000213363358 0.7391793761185131 1.0924709746511518 1.218196249170184 1.0033505818457158 1.0257400972180353 1.0153795511491934 1.0312844102816316 0.9665858316064422 1.0 13.708890477548147 -5.280168559621935 24.970679512960753 1.048320504090541 0.8706896770636642 0.37992598231373287 0.08849853808656923 697.7074317122548 930217.7152130274 0.023273193344981586 0.048580687080168175 5.2460380999387815e-06 5.280168559621935 -0.17763082702687683 S(ph)RT(ph)PLLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRTPLLPR 8 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 S(1)RT(1)PLLPR 77.288 0.016863 0.0 1138.2 703.47 904.14 2286.2 1116.9 803.74 1215.1 973.41 592.24 582.04 True False 1330.874779525284 773.3058525287344 925.6981265700447 2158.111625960406 898.0514627337363 761.5904594965942 1099.9969314378193 947.8590189131475 600.9003895919977 687.5592445738947 1.9356510584772593 1.1247115919559483 1.3463539816757657 3.138800973140672 1.3061441175011634 1.1076724885992615 1.5998576706208454 1.3785852294089507 0.8739616176121628 1.0 9.425340220638216 -6.487055668232647 24.99939435051823 1.2373598089959414 1.8470351570740722 0.2796228907373123 0.5296707201932709 932.0444269065578 650434.5128969188 0.17064078011906045 0.19341463178225268 3.25794937655797e-07 6.487055668232647 0.6096753480781307 S(ph)RTGSES(ph)SQTGTSTTSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 S(0.961)RT(0.379)GS(0.157)ES(0.461)S(0.04)QT(0.002)GT(0.001)STTSSR 78.122 0.01488 15701000.0 6193.1 6521.7 9504.9 9341.7 12158.0 11568.0 12440.0 10854.0 11962.0 8552.9 True False 7241.469510699388 7169.131275586228 9731.532863533981 8818.31483520003 9775.727176933258 10961.353715699857 11261.593142199386 10569.094000763607 12136.921620119336 10103.473065280858 0.7167307186262181 0.7095709791340885 0.9631868962936125 0.8728003507529415 0.9675610667510115 1.0849094806187967 1.1146259379755505 1.0460852354902384 1.2012623324375589 1.0 13.302563683691584 -5.487631285500906 0.5982882585054425 1.1073549016044435 0.5936248348303961 0.7999008134661756 0.0686765726332063 0.747861183530473 0.3572429501997162 0.039291148091184676 0.23887416972221023 3.2536341255991933e-06 5.487631285500906 -0.5137300667740474 S(ph)RTGSESS(ph)QTGTSTTSSR ddPTM_PC-9_AZD4547_30min_R2 1 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 S(0.909)RT(0.135)GS(0.171)ES(0.192)S(0.466)QT(0.09)GT(0.018)S(0.014)T(0.004)T(0.001)SSR 99.31299999999999 0.01958 29068000.0 8844.5 6461.4 11777.0 19081.0 13594.0 12948.0 10306.0 11297.0 10949.0 13524.0 True False 11656.867022971617 8549.921190436271 11620.829285044902 14682.170248511293 11706.70774952045 12138.3595131416 11223.214034632532 9551.308229234519 11527.741787173483 13050.528876385231 0.893210316101792 0.6551398239428631 0.8904489155280632 1.1250249233254062 0.897029374089474 0.9301047971401228 0.8599815487126194 0.7318713532382195 0.8833160630013077 1.0 13.671820653155143 -12.316751655146193 0.010285768156598233 1.8834812864652335 3.8679580948989255e-06 0.04758761876854334 0.11952485119380109 41280.40809102508 48.22134724731216 4892.6574288125075 3977.197873862992 4.822234711326632e-13 12.316751655146193 -1.8834774185071386 S(ph)RTGSESS(ph)QTGTSTTSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 S(0.982)RT(0.018)GS(0.002)ES(0.159)S(0.22)QT(0.024)GT(0.116)S(0.084)T(0.187)T(0.02)S(0.167)S(0.02)R 133.93 0.0013657 8163600.0 7119.0 5485.6 10853.0 12294.0 11724.0 12308.0 15471.0 15372.0 11926.0 8698.6 True False 8324.106093340799 6030.1741149325835 11111.776680231702 11605.207037685768 9426.76636143819 11662.546813004314 14005.474879659707 14968.501287980307 12100.395188224651 10275.587321920288 0.8100856751597534 0.5868447151501286 1.0813763079534755 1.1293959823521798 0.9173944093033632 1.1349761767996764 1.3629853399992695 1.4567051808366136 1.1775867217255418 1.0 13.32693323595821 -5.515413735898382 0.6577249017562621 1.2604644355952177 0.5772636605984806 0.526313632775198 0.16629954188104829 1.1572889626096325 0.7019725936002662 0.09172111906056941 0.5221611513687194 3.0520121914454305e-06 5.515413735898382 -0.6832007749967371 S(ph)RTGSESS(ph)QTGTSTTSSR ddPTM_PC-9_Lapatinib_30min_R1 2 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 S(0.633)RT(0.141)GS(0.215)ES(0.144)S(0.709)QT(0.151)GT(0.004)S(0.001)T(0.002)TSSR;S(0.666)RT(0.303)GS(0.031)ES(0.363)S(0.482)QT(0.091)GT(0.002)S(0.005)T(0.015)T(0.041)S(0.001)SR 166.29 3.7268000000000004e-23 7532000.0 13098.8 7670.0 10355.1 9974.7 9802.2 9673.4 7491.700000000001 8854.2 11930.400000000001 10995.2 True False 12912.008709974274 7652.240586243392 9503.743649841937 10708.272712623768 9225.653867866675 9259.691231796769 7879.583568830371 9265.598455846268 10586.672719318458 12895.705669816925 1.0012642224144048 0.5933944820215509 0.7369696465766854 0.8303750866218234 0.715405120439419 0.7180445544340828 0.6110238377472393 0.7185026312699495 0.8209455915310723 1.0 13.654603100989094 -8.616034399687116 3.0795108769316006 0.9997283949410674 0.7333079899161009 0.3455613539875476 0.10802109478546722 0.415403150770632 9.180365990735876 0.09985295459534274 0.026535534849510288 2.4208372889613732e-09 8.616034399687116 -0.26642040502496644 S(ph)RTGSESSQTGTSTTSSR ddPTM_PC-9_AZD4547_30min_R2 3 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 S(0.494)RT(0.494)GS(0.012)ESSQTGTSTTSSR;S(0.494)RT(0.494)GS(0.011)ESSQTGTSTTSSR;S(0.497)RT(0.497)GS(0.005)ESSQTGTSTTSSR 183.27 8.186399999999998e-11 84484000.0 2801.54 2060.4300000000003 4005.1600000000003 8847.6 7251.040000000001 6188.0 2391.1099999999997 7521.7 3769.26 4186.13 True False 3692.3714443480026 2726.4237035952897 3952.0489614749454 6807.922514057361 6244.358258061106 5801.063381782535 2603.914157806151 6359.394096471033 3968.4953885031987 4039.574862858804 0.9140495150360735 0.6749283764147898 0.9783328928525126 1.685306683297707 1.5457958993343124 1.4360578968642077 0.6446010400122558 1.5742731134757322 0.9824042190654434 1.0 11.979987752015587 -5.532800774442085 24.67848908758114 1.2872956050768214 0.8025242919298057 0.2833856381715463 0.30773266795619547 200.66833222569716 499108.87709711125 0.0841928846099707 0.1460507442034649 2.9322380534764314e-06 5.532800774442085 -0.4847713131470157 S(ph)RTGSESSQTGTSTTSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 S(0.483)RT(0.483)GS(0.034)ESSQTGTSTTSSR;S(0.437)RT(0.437)GS(0.125)ES(0.001)SQTGTSTTSSR;S(0.734)RT(0.206)GS(0.059)ES(0.001)SQTGTSTTSSR 90.87200000000001 0.00061118 18328580.0 1147.6 1677.35 2127.7 2657.76 3325.6600000000003 5096.72 3209.5 3116.4 3594.4700000000003 2600.5 True False 1341.866013866822 1843.8662227800344 2178.432437347184 2508.8543237741787 2674.0207964500632 4829.439030937224 2905.472925232227 3034.5978020987386 3647.0323236808545 3071.9500644533277 0.4368124434684179 0.6002266261148231 0.7091366694252725 0.8166976256564394 0.8704636274502469 1.5721085726035888 0.9458073420048493 0.9878408627839346 1.1872042992762208 1.0 11.584939049434999 -5.9387272228192645 1.2936320442440912 1.1202388220331252 0.521781219455252 0.6318012156932808 0.1821476234627063 0.30469461548184107 1.0341401989357748 0.06752828053536468 0.13528279281044825 1.1515234252765866e-06 5.9387272228192645 -0.5984576025778732 S(ph)RTGSESSQTGTSTTSSR ddPTM_PC-9_Lapatinib_30min_R1 5 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 S(0.497)RT(0.497)GS(0.007)ESSQTGTSTTSSR;S(0.499)RT(0.499)GS(0.001)ESSQTGTSTTSSR;S(0.498)RT(0.498)GS(0.004)ESSQTGTSTTSSR;S(0.471)RT(0.471)GS(0.056)ES(0.001)S(0.001)QTGTSTTSSR;S(0.382)RT(0.382)GS(0.193)ES(0.031)S(0.01)QT(0.001)GTSTTSSR 108.96 0.00012261 79475110.0 4328.7300000000005 1471.5900000000001 3366.1 767.26 4274.37 4068.7699999999995 3967.9 4137.13 5289.5 2445.12 True False 4267.00151640814 1468.182623769221 3089.352251521755 823.6868599043285 4022.959960334752 3894.758191866123 4173.338446916189 4329.356163135602 4693.740809095668 2867.7557340823946 1.4879236281166277 0.5119622310646343 1.0772717546357782 0.2872235072586774 1.4028251822577182 1.3581206187047663 1.4552628723978636 1.509666988608038 1.6367296395965676 1.0 11.485706429958618 -6.404456054992441 12.347076344620463 1.4225073263720942 0.8345359331027713 0.39262980124437186 0.33565851614416525 0.6019508543625895 59.73543191681906 0.0979039732400741 0.1110039704753046 3.940432977337252e-07 6.404456054992441 -0.5879713932693229 S(ph)RTPLISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRTPLISR 8 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.958)RT(0.042)PLISR 61.765 0.030476 2181000.0 5498.8 6992.0 6505.1 5606.3 6271.3 5739.4 5369.0 5964.1 4245.0 2620.2 True False 6429.638233749458 7686.119551481811 6660.206254729134 5292.197186869834 5042.48378390373 5438.415760363746 4860.409451806148 5807.5486944863 4307.075094249002 3095.2215185082105 2.0772788620467852 2.483221154131241 2.1517704677690155 1.7097959403630953 1.6291188704109398 1.7570360401813419 1.570294540388404 1.8762950114424564 1.3915240213000533 1.0 11.595826948452846 -1.5228787486225488 0.08915022423076008 0.4779639133055809 5.625027903479052 0.7645713253928075 0.19161372329913776 79.79514021785226 0.5141198895243176 3.9326332434908253 50.239815958848034 0.02999999976912823 1.5228787486225488 5.1470639901734705 up S(ph)RTPLLPR ddPTM_PC-9_AZD4547_30min_R2 1 SRTPLLPR 8 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.909)RT(0.091)PLLPR 61.765 0.030476 4896500.0 5793.8 4908.3 5852.3 9195.8 6641.0 8708.6 6710.9 8748.0 5329.5 8714.1 True False 7636.10788147356 6494.8119879621045 5774.694678175109 7075.850383693737 5719.011782004214 8164.049865318585 7308.157099264064 7396.197609041647 5611.206489610109 8409.02201136561 0.9080851341752487 0.7723623483424986 0.6867260747290289 0.8414593723419962 0.6801042706600617 0.9708679385407814 0.8690852621608528 0.8795550301860273 0.6672840767958531 1.0 13.037722306141621 -6.759305727905384 24.999282588371535 0.8693135651118465 0.7759310938110537 0.1857820949821023 0.10354942115188609 107.9101407085414 1264349.811796353 0.034381394610998 0.032792119768757434 1.7405811346454076e-07 6.759305727905384 -0.0933824713007928 S(ph)RTPLLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRTPLLPR 8 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.988)RT(0.012)PLLPR;S(0.993)RT(0.007)PLLPR 70.908 0.021656 0.0 9425.1 11027.2 12742.2 15276.2 14451.2 11996.2 12209.4 9548.5 10181.2 8972.599999999999 True False 11020.583275789631 12121.907539774058 13046.022373062597 14420.324040108628 11619.591098807212 11367.098153896839 11052.837243598804 9297.86199247202 10330.08078906195 10599.261352937476 1.039750121147394 1.1436558771536092 1.2308425972954262 1.3605027331562292 1.0962642312416386 1.0724424821118845 1.0427931603493883 0.8772179195199498 0.9746038374833615 1.0 13.371676108528042 -7.051489888945301 1.5561558877982313 0.9523378879531799 1.1894142039361775 0.5589784713198102 0.08589629497076677 0.3000903156360049 1.4588604899498412 0.046863529593534806 0.033521255407227626 8.881986547322036e-08 7.051489888945301 0.2370763159829976 S(ph)RTPLLPR ddPTM_PC-9_Lapatinib_30min_R1 2 SRTPLLPR 8 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.93)RT(0.07)PLLPR;S(0.996)RT(0.004)PLLPR 77.192 0.011271999999999999 3831500.0 14955.8 9230.5 11557.7 10014.9 10007.400000000001 9799.4 8628.1 9429.7 10985.4 8762.5 True False 14742.527549442184 9209.127344370232 10607.470520012184 10751.42915472703 9418.7844073054 9380.302505517113 9074.820800382471 9867.838286812308 9748.108570609615 10277.086449702678 1.4345045769142766 0.8960834755493039 1.032147639501375 1.0461553678025228 0.9164839133544402 0.912739476448453 0.8830149327628757 0.9601785812649061 0.9485284198316375 1.0 13.327143698523342 -4.757208698261781 24.999999999946873 0.9542723386614784 1.434505281326266 0.879739788219146 0.05318129544391662 42.697007746042694 252272.6366810555 0.01416509760891137 0.10737941979964556 1.74900600966978e-05 4.757208698261781 0.48023294266478755 S(ph)RTPPSAASSR ddPTM_PC-9_AZD4547_30min_R2 1 SRTPPSAASSR 11 1 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 S(0.858)RT(0.142)PPSAASSR 62.166000000000004 0.026531 1456900.0 1301.5 567.97 2549.9 3971.1 3249.9 3938.4 1037.9 3606.7 2418.4 2495.5 True False 1715.349927118272 751.5551952412931 2516.0866599249384 3055.6242478834024 2798.707482357401 3692.131225406 1130.2710893212784 3049.3673887209106 2546.2316867385484 2408.1333045710844 0.7123151878105001 0.31209036219660335 1.044828645967787 1.2688767029978198 1.162189600154167 1.533192210911933 0.4693556985303986 1.2662784833931928 1.057346651825847 1.0 11.233699540763258 -5.3408847595294535 6.204488878617081 1.1143244228198745 0.5150071060845827 0.4281316327598619 0.2719922960837309 0.18962690096720974 11.851501470418592 0.0700006184549918 0.14862303727711199 4.561579418546949e-06 5.3408847595294535 -0.5993173167352919 S(ph)RTPPSAASSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRTPPSAASSR 11 1 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 S(0.628)RT(0.372)PPSAASSR;S(0.69)RT(0.31)PPSAASSR 63.623999999999995 0.023607 2941800.0 6311.0 7614.599999999999 8412.2 6124.700000000001 9656.9 6467.9 6446.1 7085.6 6222.1 5823.3 True False 7379.327652068241 8370.527164861754 8612.77875144616 5781.552915545311 7764.69976763669 6128.711937912789 5835.478742277449 6899.610507813768 6313.086441443285 6879.018192782562 1.0727297770211746 1.2168200359818901 1.252036047888731 0.8404619312696822 1.1287511604175406 0.8909282932763586 0.8483011061665761 1.0029934962307283 0.9177307378060069 1.0 12.747986955769674 -5.755501064871898 24.99992985821186 0.9482697560532586 1.184157789265118 0.582084159787432 0.09064863304395195 98.79366642672164 415909.3813539451 0.024424943988010605 0.04091873230799531 1.7558965888089005e-06 5.755501064871898 0.23588803321185947 S(ph)RTPPSAASSR ddPTM_PC-9_Lapatinib_30min_R1 1 SRTPPSAASSR 11 1 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 S(0.977)RT(0.023)PPSAASSR 82.20200000000001 0.0067033 1127300.0 3878.0 3778.2 4085.6 3446.2 2882.4 2458.9 3111.3 2348.3 3075.9 2651.7 True False 3822.6990088618986 3769.4518100319174 3749.6977388720748 3699.6450441861903 2712.862899016435 2353.738578975861 3272.38789029218 2457.4105908906267 2729.4597513370577 3110.042811831847 1.2291467481794214 1.2120256980680186 1.2056739941349761 1.1895801016343766 0.8722911751232554 0.7568187068104972 1.05220027127688 0.7901532999937023 0.8776277101244719 1.0 11.602718724822589 -6.246551508431375 6.344063311534709 0.8818711172132432 1.2105233133298532 0.7809266045616418 0.08233552739324052 0.0708731114265655 12.99851921490308 0.0240404318817872 0.029932822018468926 5.668243407263109e-07 6.246551508431375 0.32865219611661 S(ph)RTPPSAPSQSR ddPTM_PC-9_AZD4547_30min_R2 5 SRTPPSAPSQSR 12 1 Q9UQ35;I3L3Q8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.5)RT(0.5)PPSAPSQSR;S(0.499)RT(0.499)PPSAPS(0.001)QS(0.001)R;S(0.5)RT(0.5)PPSAPSQSR;S(0.629)RT(0.37)PPSAPSQSR;S(0.499)RT(0.499)PPSAPS(0.001)QSR 127.3 0.00115 181541300.0 108905.0 106925.4 119570.3 166359.0 184945.2 132297.0 112384.5 138564.6 113557.7 144230.8 True False 143534.52463527903 141486.9445098391 117984.71969615393 128007.50277092865 159268.7513665301 124024.44767609626 122386.50278237516 117152.62496774252 119560.12818936058 139181.3235924391 1.0312771924456423 1.0165655912581453 0.8477051133788999 0.9197175272292248 1.1443255981162566 0.8910997860551585 0.8793313615895495 0.8417266192323144 0.8590242218091363 1.0 17.086606106828278 -6.958871789563492 24.999988343867273 0.882314017348989 0.9849093733887575 0.253409092307026 0.08227347536412401 209.2128895692178 127170.50964639618 0.029801422271932852 0.026282355513333747 1.0993303308199051e-07 6.958871789563492 0.10259535603976855 S(ph)RTPPSAPSQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SRTPPSAPSQSR 12 1 Q9UQ35;I3L3Q8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.587)RT(0.412)PPSAPSQSR;S(0.5)RT(0.5)PPSAPSQSR;S(0.849)RT(0.151)PPSAPSQSR;S(0.997)RT(0.003)PPSAPSQSR 115.06 0.0017753 702842300.0 91401.2 103184.2 110714.5 109503.20000000001 120020.90000000001 111041.40000000001 103917.70000000001 116153.4 101959.40000000001 73737.6 True False 106873.61790401218 113427.64545537908 113354.3535670793 103368.09071816414 96503.66622223951 105218.19350678724 94073.8631570041 113104.49632470023 103450.36333676602 87105.6431734795 1.2269425264579334 1.3021848105693532 1.3013433967914443 1.1866979790539673 1.1078922410347503 1.2079377371364424 1.0799973426480154 1.2984749575804342 1.1876424944217954 1.0 16.410478566969076 -14.52287874528033 0.10783015277913156 0.3780268408178885 1.3277698830258031 0.46472898242483407 0.07070467479580331 171.17139657679328 1.2289063600747396 24.0469782026311 1.0108683799165263 3.0000000000000503e-15 14.52287874528033 0.9497430422079146 S(ph)RTPPSAPSQSR ddPTM_PC-9_Lapatinib_30min_R1 3 SRTPPSAPSQSR 12 1 Q9UQ35;I3L3Q8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.62)RT(0.378)PPSAPS(0.002)QSR;S(0.499)RT(0.499)PPSAPS(0.001)QSR;S(0.5)RT(0.5)PPSAPSQSR 72.289 0.011976 769971200.0 11340.599999999999 10291.6 13045.7 10163.59 12702.199999999999 10506.599999999999 11236.4 9886.27 14106.1 10885.8 True False 11178.880964388662 10267.770432514022 11973.132903858283 10911.054313342327 11955.08156948605 10057.257210080837 11818.165811872546 10345.622195803038 12517.32247418176 12767.396025583264 0.8755803408924152 0.8042180576164082 0.9377897325238882 0.854602950474693 0.9363758706576109 0.7877297132420847 0.9256520114353268 0.8103157585988965 0.9804131123605465 1.0 13.640176689707184 -8.371471411836755 6.097334981804801 0.9974950209065575 0.8682938878300157 0.4756656393293064 0.05201117464351761 0.1929172839277567 8.861040520482245 0.04592375173412689 0.01192087048707576 4.251366912198471e-09 8.371471411836755 -0.1292011330765418 S(ph)RTPVQDHR ddPTM_PC-9_AZD4547_30min_R2 2 SRTPVQDHR 9 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.5)RT(0.5)PVQDHR;S(0.878)RT(0.122)PVQDHR 94.538 0.0026966 288810000.0 741785.5 650562.5 893681.6 1225914.8 1141383.2 940506.2 782419.8 1037986.3 821465.5 1021574.8 True False 977657.858903107 860844.1056819251 881830.7980628159 943299.0830548548 982921.8443881469 881696.1986359785 852053.6464520075 877589.3678872887 864886.489274944 985809.7771951682 0.9917307390526648 0.873235512160575 0.8945242971436195 0.9568773863642689 0.9970704968911568 0.8943877602275215 0.8643185188082386 0.8902218137704123 0.8773360837784792 1.0 19.910949764069443 S(ph)RTPVQDHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SRTPVQDHR 9 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.651)RT(0.349)PVQDHR;S(0.69)RT(0.31)PVQDHR;S(0.5)RT(0.5)PVQDHR;S(0.5)RT(0.5)PVQDHR 99.539 0.0019386 455300200.0 589385.9 792295.1 830218.9 766736.7 1039723.2 868522.7 775059.8 806411.0 859962.0 662100.4999999999 True False 689157.2919678545 870948.9214320986 850014.4671987118 723778.9284929207 835996.9026754432 822975.8406651696 701640.5247969805 785243.565713083 872537.3173617346 782134.0794653251 0.8811242344010499 1.1135544969827784 1.0867886843388674 0.9253898372357121 1.0688664829014218 1.0522183629023867 0.8970847112001937 1.003975643472643 1.115585345620293 1.0 19.577056421098128 -10.94351445759675 4.1747579140933375 0.999934769780525 1.0171071063581467 0.003203009796094558 0.08321576055701682 4.962174453610972e-05 6.886327403798796e-06 0.07913237055792695 0.01911951124248725 1.1388998674425685e-11 10.94351445759675 0.01717233657762174 S(ph)RTPVQDHR ddPTM_PC-9_Lapatinib_30min_R1 3 SRTPVQDHR 9 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.593)RT(0.407)PVQDHR;S(0.5)RT(0.5)PVQDHR;S(0.5)RT(0.5)PVQDHR 89.35600000000001 0.0044393 4496510.0 13055.51 10534.7 15446.599999999999 8473.2 14187.599999999999 11676.199999999999 9966.8 10508.8 17251.4 7812.9 True False 12869.33603331269 10510.307549400033 14176.640173600303 9096.3473937666 13353.113261894809 11176.8361445516 10482.832136073057 10997.077212260529 15308.365666704418 9163.349354965136 1.404435816510638 1.1469940894161208 1.5471024430514295 0.9926880490306494 1.4572306200089884 1.2197326230386996 1.143995686510955 1.2001154584706293 1.6706081012189742 1.0 13.161659308157356 S(ph)RTSPITR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRTSPITR 8 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.877)RT(0.115)S(0.005)PIT(0.003)R 54.776 0.043429 342320000.0 4820.3 4123.3 5119.9 1501.4 3352.0 5937.5 3187.2 4318.5 4300.2 3372.3 True False 5636.281584735309 4532.633974059629 5241.977833328875 1417.2814256044758 2695.199662533337 5626.127047628628 2885.2853426702463 4205.143950828974 4363.082289820863 3983.671294887889 1.414846047154583 1.1378032067746666 1.315866055529162 0.35577268320888455 0.6765617600006295 1.412297007247673 0.7242779659990611 1.0555951130368848 1.0952415414946155 1.0 11.959882895722862 S(ph)RVFDLQFSTDSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRVFDLQFSTDSPR 14 1 C9J470;E9PHA2;Q15003;C9JZP1 C9J470 NCAPH Condensin complex subunit 2 1 S(0.998)RVFDLQFST(0.001)DSPR 52.008 0.043680000000000004 3280200.0 6498.7 5422.2 6679.2 5550.1 10694.0 6262.7 4864.4 6195.7 6249.4 6051.5 True False 7598.801554824258 5960.480181928584 6838.457459007057 5239.145890666977 8598.587467521327 5934.272987146746 4403.608816793785 6033.069439886779 6340.785652296758 7148.589046352355 1.0629792124785282 0.8337981304114809 0.9566163916635345 0.7328923031797874 1.2028370090610887 0.8301320650366346 0.6160109062418093 0.8439524780019657 0.8869982049859493 1.0 12.803442802538683 -6.970120353383265 24.999921647135874 0.8093553924968745 0.9461822419157869 0.13391563126464212 0.14788430653717113 372.1523618153219 311374.11104735016 0.050900003955421325 0.044889077610115284 1.0712224027634588e-07 6.970120353383265 0.13682684941891243 S(ph)RVTVAR ddPTM_PC-9_AZD4547_30min_R2 1 SRVTVAR 7 1 Q9BST9 Q9BST9 RTKN Rhotekin 1 S(0.944)RVT(0.056)VAR 66.29899999999999 0.025769999999999998 5793600.0 10041.0 5529.3 13910.0 13110.0 7686.2 7300.9 13725.0 5248.2 6686.5 7815.5 True False 13233.829134225567 7316.538093645227 13725.544311367452 10087.6920474809 6619.103803469471 6844.373568851991 14946.498411151902 4437.211281638363 7039.934739239705 7541.881723853063 1.7547118370167907 0.9701210336546208 1.8199097803346649 1.3375563840488354 0.8776461957146479 0.907515368108329 1.9817996301745109 0.5883427298527617 0.9334453916154868 1.0 12.880708810141844 -5.73034266302707 0.3174887846041054 0.9175329904421287 1.759639812925057 0.1790721846632075 0.4098995232367042 7.863466897172567 1.0187471830858676 0.4855834001577779 2.4457718269561557 1.8606185092999682e-06 5.73034266302707 0.8421068224829283 S(ph)RVTVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRVTVAR 7 1 Q9BST9 Q9BST9 RTKN Rhotekin 1 S(0.961)RVT(0.039)VAR 77.732 0.013854 3315900.0 7964.6 6323.8 5542.9 9466.3 5033.1 4951.0 6079.2 8720.7 4384.5 1590.1 True False 9312.84947197951 6951.585071461764 5675.063757565311 8935.933901158682 4046.90018541066 4691.360844262623 5503.33416640342 8491.790865345429 4448.615017840934 1878.3725427753263 4.957935265716578 3.700855348529894 3.0212663506996917 4.757274554256257 2.1544715402575565 2.497566769865077 2.9298416800067537 4.520823570386452 2.3683347773323136 1.0 10.87526750969448 -7.869703598196 0.11720772875538582 7.946104599143779e-27 5.765011677685701 0.4555664823253256 0.8956133550624792 8.20773877627889 0.9839766004925108 21.364691644576293 22.287495087306745 1.3498838510161259e-08 7.869703598196 5.765011677685701 S(ph)RWQRS(ph)LMS(ph)Y(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 SRWQRSLMSYK 11 2 A6NGQ3;Q5VST9;Q5VST9-2;Q5VST9-6 A6NGQ3 OBSCN Obscurin 4 S(1)RWQRS(1)LMS(1)Y(1)K 46.70399999999999 0.044976 0.0 2611.1 1087.2 2682.8 2622.2 3182.9 2403.7 2925.8 2399.7 2787.4 2712.5 True False 3441.375485746079 1438.6161386452343 2647.2243190896215 2017.6923025861483 2741.009275853215 2253.396259015946 3186.190531974368 2028.8815046201696 2934.7362734101157 2617.5362006207433 1.3147384494357572 0.5496069694486247 1.0113420087415936 0.7708364461617214 1.0471714871424473 0.8608844677989773 1.2172479338466338 0.7751111538167168 1.1211826880232445 1.0 11.35399377448097 -6.290907106621675 24.835841347809748 0.9959018334459873 0.8928942594742036 0.03882064260177165 0.21425210787285923 2151.0127868024833 1812899.0212369617 0.061661726781144816 0.06992714833025837 5.117912933853531e-07 6.290907106621675 -0.10300757397178362 S(ph)RWSGSQQVEQPTGSVLWMAPEVIR ddPTM_PC-9_Lapatinib_30min_R1 1 SRWSGSQQVEQPTGSVLWMAPEVIR 25 1 P04049;P04049-2;H7C155 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 S(0.738)RWS(0.131)GS(0.131)QQVEQPTGSVLWMAPEVIR 74.278 8.8417e-05 1563700.0 6070.4 3903.7 5093.8 3368.4 4329.7 4507.8 4151.2 3320.7 3740.8 2850.8 True False 5983.834982824977 3894.661222492612 4675.007426636622 3616.123372652999 4075.035558517715 4315.011902195042 4366.1288240224 3474.9918448113535 3319.4717116296583 3343.556981547776 1.789661434169721 1.1648257361804322 1.3982137742639875 1.0815198881339383 1.2187725769313278 1.2905453461713001 1.305833532408131 1.0393098918274557 0.9927965128002788 1.0 11.707167988879638 -2.6463777435351634 1.3376697276538119 1.1670698492431892 199.99951326750735 0.6521170898864974 0.13486646084929702 302.71198685458256 2.221027585866685 0.03927052291664103 183000.44389531144 0.0022574713976061854 2.6463777435351634 198.83244341826418 S(ph)S(ph)DQLY(ph)ELLNISQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSDQLYELLNISQSR 15 0 Q8NDB2-3;Q8NDB2-2;Q8NDB2 Q8NDB2-3 BANK1 B-cell scaffold protein with ankyrin repeats 3 S(1)S(1)DQLY(1)ELLNISQSR 57.425 0.020097 1201000.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 S(ph)S(ph)EMS(ph)PVPMRSAGQTTK ddPTM_PC-9_Lapatinib_30min_R1 1 SSEMSPVPMRSAGQTTK 17 1 E9PCH4;Q8TEU7;A0A5F9ZHG7;Q8TEU7-4;B7Z7Y1;Q8TEU7-2;Q8TEU7-5;Q8TEU7-3;D6RE77 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 3 S(0.972)S(0.973)EMS(0.935)PVPMRS(0.044)AGQT(0.048)T(0.027)K 47.537 0.041311 0.0 686.14 459.61 526.21 771.03 553.9 508.98 637.64 0.0 889.02 516.24 True False 676.3555177773347 458.54580128335436 482.94704502934053 827.7341182806796 521.3206910092994 487.21211189033045 670.6538792035182 0.0 788.8892058043728 605.4713961534388 1.1170726182512054 0.7573368522385977 0.7976380851308653 1.367090375431897 0.8610162169860557 0.8046822938054384 1.1076557595687984 0.0 1.302933897152182 1.0 9.241914995107486 S(ph)S(ph)GKSSSGS(ph)S(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 SSGKSSSGSSK 11 1 H0YDX2;H0YDT8;Q9NPA0 H0YDX2 EMC7 ER membrane protein complex subunit 7 4 S(0.855)S(0.856)GKS(0.084)S(0.201)S(0.024)GS(0.988)S(0.992)K 66.62100000000001 0.045954 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 S(ph)S(ph)GKSSSGS(ph)S(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSGKSSSGSSK 11 1 H0YDX2;H0YDT8;Q9NPA0 H0YDX2 EMC7 ER membrane protein complex subunit 7 4 S(1)S(1)GKSSS(0.001)GS(0.999)S(0.999)K;S(0.985)S(0.981)GKS(0.016)S(0.016)S(0.002)GS(1)S(1)K 93.178 0.0052261 4152500.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 S(ph)S(ph)HET(ph)LNIVEEKKR ddPTM_PC-9_Lapatinib_30min_R1 1 SSHETLNIVEEKKR 14 2 E9PK52;E9PHY5;O43491-4;E9PMG5 E9PK52 EPB41L2 Band 4.1-like protein 2 3 S(1)S(1)HET(1)LNIVEEKKR 75.911 0.045355 0.0 10233.0 13703.0 16941.0 11505.0 16701.0 16499.0 15931.0 17030.0 18012.0 14570.0 True False 10087.07554349763 13671.271545409814 15548.176374151124 12351.116079554904 15718.680015429332 15793.376231047505 16755.82922901834 17821.275971071565 15983.29888523135 17088.405086695333 0.5902877121839306 0.8000320378672422 0.909867029443058 0.7227775802887081 0.9198447681736875 0.9242159318510006 0.9805379228787169 1.0428870266510026 0.9353300559146743 1.0 14.060730131689867 -3.707388320823908 0.3351231939544908 1.0118410334316723 1.887335299131523e-18 0.7336135814262323 0.0679871212603012 7.687600443970934 0.3957084835019714 0.06635433432032466 3.6246349000392644 0.0001961605539070075 3.707388320823908 -1.0118410334316723 S(ph)S(ph)HS(ph)HTS(ph)KKHKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSHSHTSKKHKK 12 3 Q8WUA2 Q8WUA2 PPIL4 Peptidyl-prolyl cis-trans isomerase-like 4 4 S(0.998)S(0.998)HS(0.967)HT(0.482)S(0.556)KKHKK 56.093999999999994 0.030512 9962000.0 20787.0 24997.0 29388.0 37353.0 52874.0 42321.0 59876.0 51245.0 54287.0 39974.0 True False 24305.828538035592 27478.536960582205 30088.721374610657 35260.23251005991 42513.719259184836 40101.61225813743 54204.11181529989 49899.87304856561 55080.844674086184 47220.96976599009 0.5147253150133598 0.5819138636236362 0.6371898231594859 0.7467070812987697 0.9003144041697434 0.8492331363982231 1.147882224442143 1.0567312212318212 1.1664488244745241 1.0 15.52714004971021 -6.286073569602403 0.7191917369414886 1.1099542772653197 0.5064363034771486 0.9093160681423368 0.06705691800579357 0.20112745673210972 0.22475901292541292 0.039719487954994165 0.06933951740655685 5.175191566399106e-07 6.286073569602403 -0.6035179737881711 S(ph)S(ph)IVS(ph)LY(ph)KK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSIVSLYKK 9 1 Q6AI14;Q9UBY0 Q6AI14 SLC9A4;SLC9A2 Sodium/hydrogen exchanger 4;Sodium/hydrogen exchanger 2 4 S(1)S(1)IVS(1)LY(1)KK 55.353 0.033357 0.0 3203.8 3985.2 4719.2 4471.2 2738.1 4163.0 5199.8 4707.0 3794.4 3486.0 True False 3746.1400620656377 4380.824318730735 4831.723625665664 4220.693159825982 2201.588960615312 3944.6849514573405 4707.237300708068 4583.446237478749 3849.8859217004524 4117.984204839184 0.9097023873145071 1.0638273730099983 1.1733225251295867 1.0249415611808566 0.5346278302933143 0.957916484191903 1.143092607100443 1.1130315245242042 0.934895747578711 1.0 12.007722580964483 -9.746161355573603 15.659566620494289 1.0000141123863309 0.9875539419529694 0.00038490740675900526 0.17219655300126743 0.0 0.0 0.17979139991226986 0.04360581955387968 1.794066944440516e-10 9.746161355573603 -0.01246017043336145 S(ph)S(ph)LS(ph)T(ph)QDT(ph)LLIK ddPTM_PC-9_AZD4547_30min_R2 1 SSLSTQDTLLIK 12 0 Q9NR99 Q9NR99 MXRA5 Matrix-remodeling-associated protein 5 5 S(1)S(1)LS(1)T(1)QDT(1)LLIK 47.706 0.044807 0.0 3147.9 1187.7 1431.2 3905.0 4115.4 1711.4 1121.7 2926.9 3502.8 1401.6 True False 4148.866719612453 1571.6007982606181 1412.2213528705329 3004.7625816485815 3544.0477469748735 1604.3858874567918 1221.5291269791678 2474.6148584709645 3687.9508568920683 1352.5304106138383 3.0674849800453017 1.1619707667403618 1.044132791239499 2.2215859681002565 2.620309102969764 1.1862105834120582 0.9031435577295328 1.829618645948134 2.7267045738500717 1.0 10.401445316975577 S(ph)S(ph)S(ph)LT(ph)PGIGGPDSMPPRT(ph)PKNLYNTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSLTPGIGGPDSMPPRTPKNLYNTVK 27 2 H7C1N4;A6NL88 H7C1N4 SHISA7 Protein shisa-7 5 S(0.845)S(0.845)S(0.845)LT(0.845)PGIGGPDS(0.379)MPPRT(0.795)PKNLY(0.357)NT(0.09)VK 45.784 0.0094013 1640500.0 2678.9 3929.3 3720.3 3322.4 3749.9 2955.0 4532.2 3728.6 3918.2 3054.2 True False 3132.384859313199 4319.3749361609625 3809.0060613163173 3136.2566993661317 3015.1340138823875 2800.034598019805 4102.877205713509 3630.728200778256 3975.4962624938653 3607.9022829661026 0.8682011356299886 1.1971984265078126 1.0557398073943633 0.8692742910952053 0.8357027927606752 0.7760838233450881 1.137191887120757 1.006326645242007 1.1018857914371114 1.0 11.816944549588722 -9.69065600454853 10.766528552679603 0.9999908513250152 0.9829509257372037 0.0014289073946994746 0.13425658865893997 0.0 0.0 0.1377759299245121 0.03341557127920356 2.0386562147248186e-10 9.69065600454853 -0.017039925587811533 S(ph)S(ph)SSSSSSSGSEASSEHKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSSSSSSGSEASSEHKR 19 1 A0A1B0GV45 A0A1B0GV45 2 S(0.899)S(0.45)S(0.371)S(0.189)S(0.012)S(0.078)S(0.001)SSGSEASSEHKR 149.35 1.138e-13 0.0 0.0 994.73 0.0 0.0 1081.2 0.0 0.0 0.0 598.05 0.0 True False 0.0 1093.4802204584519 0.0 0.0 869.3466214591416 0.0 0.0 0.0 606.7953498505576 0.0 0.0 S(ph)SAIGIENIQEVQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSAIGIENIQEVQEK 15 0 J3KPC5;P47736-3;F2Z357;P47736;A0A0A0MQY8;X6R8W7;P47736-2;P47736-4 J3KPC5;P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 S(0.598)S(0.402)AIGIENIQEVQEK;S(0.975)S(0.025)AIGIENIQEVQEK 173.77 7.4382e-05 5210600.0 37186.0 44459.0 31405.0 33564.0 39030.0 29940.0 28819.0 34798.0 24439.0 25143.0 True False 43480.85534302164 48872.59570070506 32153.814304125724 31683.51789595619 31382.351679199313 28369.89369364229 26089.05568850838 33884.58937152868 24796.3741409544 29701.22686812151 1.4639413898989433 1.6454739704089558 1.0825752904718084 1.0667410486656457 1.056601190871417 0.9551758188174999 0.8783830985954962 1.140848138091467 0.8348602652359955 1.0 14.858234905188205 -5.343347833730869 4.4564827558468005 0.9986663704582656 1.554822598227131 0.8441733075164741 0.09537836289365337 0.07126353737642502 2.548829197316767 0.024648115607011245 0.05512698571010207 4.535781927553318e-06 5.343347833730869 0.5561562277688655 S(ph)SATLWNSPSR ddPTM_PC-9_AZD4547_30min_R2 4 SSATLWNSPSR 11 0 Q3KQU3-4;Q3KQU3;C9JIR3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.984)S(0.016)ATLWNSPSR;S(0.983)S(0.017)ATLWNSPSR;S(0.97)S(0.03)ATLWNSPSR;S(0.985)S(0.015)ATLWNSPSR 161.21 0.00027039999999999996 167314000.0 11735.0 17214.4 67364.0 64990.1 47576.7 81240.3 44419.8 52947.5 55714.8 66314.0 True False 15466.485896836666 22778.618154060456 66470.70934514438 50007.63653203572 40971.496438620656 76160.33119829143 48373.07614744519 44765.680487509475 58659.77058398144 63992.367044410625 0.24169266759741742 0.3559583620067081 1.0387287174267799 0.7814625218868757 0.6402559919402026 1.1901471177872862 0.7559194694872645 0.6995471890646293 0.9166682417493891 1.0 15.965612211476108 -5.172507293941844 5.559017903501437 0.8612864122342739 0.2766422423458085 0.6749468364673078 0.16077204437720005 0.12738165081335273 6.168730071029011 0.04075439339845281 0.11279654163163827 6.721910196211827e-06 5.172507293941844 -0.5846441698884655 S(ph)SATLWNSPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SSATLWNSPSR 11 0 Q3KQU3-4;Q3KQU3;C9JIR3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.966)S(0.033)AT(0.001)LWNSPSR;S(0.983)S(0.017)ATLWNSPSR;S(0.979)S(0.021)ATLWNSPSR;S(0.941)S(0.059)ATLWNSPSR;S(0.987)S(0.013)ATLWNSPSR 183.06 0.00017885 141196800.0 28575.1 42548.2 62809.2 63873.8 107176.0 83966.6 97485.8 70633.0 58976.6 53869.2 True False 33412.300046048986 46772.10410474233 64306.80953321746 60295.158067653625 86175.63216935354 79563.24368124854 88251.23928792754 68778.95859184965 59839.02120223462 63635.259531647425 0.5250595391919821 0.7350029598210623 1.0105531116948783 0.9475117805981025 1.354212001390459 1.250301236560208 1.3868292505986868 1.0808309590949987 0.9403437912039183 1.0 15.95753874656799 -5.145830299586416 1.1378362619276445 1.176704108286121 0.41740738447237824 0.6684882347844316 0.1457944787693203 0.5758889479811194 0.9439618573026072 0.050061487767147014 0.45039011059868217 7.147755698132036e-06 5.145830299586416 -0.7592967238137427 S(ph)SATLWNSPSR ddPTM_PC-9_Lapatinib_30min_R1 4 SSATLWNSPSR 11 0 Q3KQU3-4;Q3KQU3;C9JIR3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.981)S(0.019)ATLWNSPSR;S(0.986)S(0.014)ATLWNSPSR;S(0.962)S(0.037)AT(0.001)LWNSPSR;S(0.977)S(0.022)ATLWNSPSR 174.72 0.00012005 183214000.0 56045.0 51047.9 47103.0 57706.8 50525.9 80535.0 44175.9 33154.8 45882.1 28892.6 True False 55245.78802260577 50929.70172392366 43230.37316283811 61950.75057624161 47554.06589974139 77090.70578625432 46463.11194766125 34695.29304554809 40714.37473806756 33886.647413030456 1.630311412906609 1.5029430649530595 1.2757347351575035 1.8281758540804969 1.4033275502331162 2.274958181806164 1.3711333370144714 1.02386325276329 1.2014872478181964 1.0 15.048429289907784 -7.522224438109561 15.836984249510227 1.107076714256396 1.6417751748412694 0.4989043396648225 0.2594644190907361 0.21025442442846645 5028.185974368452 0.11911624080329632 0.07105391282206207 3.004523200279539e-08 7.522224438109561 0.5346984605848735 S(ph)SCSTPLSQANR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSCSTPLSQANR 12 0 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 S(0.742)S(0.017)CS(0.012)T(0.228)PLS(0.001)QANR 99.539 0.0033143 3959100.0 20966.0 17195.0 22032.0 22614.0 27230.0 22475.0 18521.0 15594.0 18570.0 13495.0 True False 24515.129702624425 18902.005962203893 22557.326436825282 21347.010895577198 21894.476972190554 21296.371435023735 16766.55679957193 15184.674023208745 18841.551119011547 15941.536673638788 1.5378147166429121 1.1857078993809043 1.415003264655564 1.3390811270331924 1.3734232414617629 1.335904553683322 1.0517528606446962 0.9525226039418393 1.1819156148333099 1.0 13.960503083193013 -7.252129560248274 4.969454221797113 1.0403070343105696 1.3596719291081556 0.7186278153166459 0.09753065498175502 0.09596060762245386 7.277931923668341 0.03720118486419814 0.02685281075728793 5.5959063755621206e-08 7.252129560248274 0.319364894797586 S(ph)SDEDAAGEPK ddPTM_PC-9_AZD4547_30min_R2 2 SSDEDAAGEPK 11 0 E9PHH9;Q9BUI4 E9PHH9 POLR3C DNA-directed RNA polymerase III subunit RPC3 1 S(0.983)S(0.017)DEDAAGEPK;S(0.985)S(0.015)DEDAAGEPK 176.99 0.00011688 29048000.0 134846.0 124327.0 147669.0 159942.0 139584.0 159771.0 124764.0 151419.0 128940.0 135686.0 True False 177724.22302895965 164513.27140300392 145710.81257478957 123069.84297926692 120205.17099522286 149780.49411292444 135867.75430010617 128020.67281246891 135755.505163773 130935.67443960438 1.3573399594083662 1.2564434567363656 1.1128427237146925 0.939925986603707 0.9180475184451653 1.1439242571130792 1.0376679608640713 0.9777371473465006 1.0368106762713611 1.0 16.9984986987263 -5.268600366956739 2.2225586020809684 1.0105236812562823 1.3427956929977756 0.7939486508013339 0.06082340113460051 0.15113973610054543 1.3855124081167034 0.017923476289803945 0.06435844302093963 5.387653204559395e-06 5.268600366956739 0.33227201174149323 S(ph)SDEDAAGEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSDEDAAGEPK 11 0 E9PHH9;Q9BUI4 E9PHH9 POLR3C DNA-directed RNA polymerase III subunit RPC3 1 S(0.989)S(0.011)DEDAAGEPK;S(0.987)S(0.013)DEDAAGEPK 166.7 0.00011464 20381300.0 107249.0 119917.0 92729.0 116209.0 136044.0 123832.0 149159.0 130156.0 102714.0 104064.0 True False 125404.13743569418 131821.567256156 94940.01103669073 109698.18648466119 109387.15480002548 117338.03192622286 135029.57970235698 126739.54291168119 104215.99793420316 122929.97942982904 1.0201265632463352 1.0723305077212875 0.7723096634119625 0.892363172868496 0.8898330196375402 0.9545111165759352 1.098426765616069 1.0309897024267114 0.8477671469366168 1.0 16.907477268913823 -7.008819463228337 24.371988685062952 1.001105600962378 0.9261118041805823 0.0919472951715038 0.09497751074456284 723.6626447799038 1999795.6670282823 0.03658739964641537 0.030651949271154996 9.798972452919275e-08 7.008819463228337 -0.07499379678179574 S(ph)SDEDAAGEPK ddPTM_PC-9_Lapatinib_30min_R1 2 SSDEDAAGEPK 11 0 E9PHH9;Q9BUI4 E9PHH9 POLR3C DNA-directed RNA polymerase III subunit RPC3 1 S(0.979)S(0.021)DEDAAGEPK;S(0.999)S(0.001)DEDAAGEPK 209.67 2.8018e-06 31114800.0 128286.0 132940.0 128040.0 125673.0 135275.0 134549.0 124085.0 131141.0 146762.0 112684.0 True False 126456.61811522867 132632.18559780924 117513.04544869317 134915.4116528385 127318.39046088267 128794.65291903813 130509.51414743203 137234.2896137581 130232.11808762614 132161.27925800814 0.9568356089256468 1.0035631188079057 0.8891639526224745 1.020839177785603 0.963356220336888 0.974526378997909 0.9875018982878373 1.0383849973625505 0.9854029774740917 1.0 17.01194003097276 -7.448367248208652 3.478747427720984 1.009548141485598 0.9683498378910864 0.20666580836242532 0.034695639733625425 0.37073704537848 8.653155120870682 0.015640855164307778 0.009633080889550135 3.561498385379279e-08 7.448367248208652 -0.0411983035945116 S(ph)SDEENGPPSSPDLDR ddPTM_PC-9_AZD4547_30min_R2 1 SSDEENGPPSSPDLDR 16 0 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 S(0.971)S(0.029)DEENGPPSSPDLDR 261.06 5.3189e-58 6904900.0 12166.0 12190.0 15217.0 14863.0 14460.0 12463.0 13113.0 14898.0 10314.0 11373.0 True False 16034.534931479748 16130.179111557583 15015.212637388837 11436.56498106092 12452.478597768551 11683.686639811855 14280.031596752988 12595.856421982451 10859.176983551679 10974.83473167178 1.461027461780942 1.4697423246846921 1.3681493165502632 1.0420717268804651 1.1346392817955158 1.0645888457977803 1.3011614248315637 1.1477035171775878 0.989461549905045 1.0 13.421911594153565 -5.633917619338014 4.398433607318473 1.1124698970816962 1.4558714592624384 0.7648256913241179 0.08592871045177457 0.1038219991943883 3.4807918246471647 0.024318448149404044 0.04364380484508651 2.323177434569972e-06 5.633917619338014 0.34340156218074225 S(ph)SDEENGPPSSPDLDR ddPTM_PC-9_Lapatinib_30min_R1 1 SSDEENGPPSSPDLDR 16 0 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 S(0.947)S(0.053)DEENGPPSSPDLDR 171.15 2.5251e-05 6912800.0 11371.0 19458.0 19229.0 9291.6 13194.0 9992.7 10140.0 11391.0 8755.3 8749.5 True False 11208.847454813984 19412.94619649595 17648.06584608652 9974.935259868964 12417.954860402053 9565.335515121427 10664.999584598954 11920.267444889972 7769.185916603708 10261.839417024088 1.0922844335508541 1.8917608634852 1.7197760682952123 0.9720416442417567 1.2101100354192869 0.9321267977798229 1.0392873198645103 1.1616111849416197 0.7570948638813095 1.0 13.325001734272915 -5.765563140339686 24.999991692495733 1.0233312300191952 1.60032254582833 0.5676927174709119 0.22224887943383895 68.69117317568958 416438.7056173629 0.059994601565349456 0.09273203416317924 1.7156822557989552e-06 5.765563140339686 0.5769913158091347 S(ph)SDELDAWTDFR ddPTM_PC-9_AZD4547_30min_R2 5 SSDELDAWTDFR 12 0 O43524;O43524-2 O43524 FOXO3 Forkhead box protein O3 1 S(0.94)S(0.06)DELDAWTDFR;S(0.984)S(0.016)DELDAWTDFR;S(0.859)S(0.141)DELDAWTDFR;S(0.978)S(0.022)DELDAWTDFR;S(0.991)S(0.009)DELDAWTDFR 187.11 0.00033969999999999996 5704500.0 12140.2 11963.759999999998 16726.399999999998 20508.6 19771.800000000003 18756.600000000002 14952.7 20106.9 17703.7 15971.300000000001 True False 16000.531068153092 15830.811455921905 16504.597007164386 15780.659124711432 17026.826856110674 17583.746836900827 16283.46133278185 16999.84061559665 18639.481439180134 15412.149648285374 1.0381764668326572 1.027164400631362 1.070882218497051 1.0239103230137045 1.1047665150334778 1.1409016417678663 1.0565340789169804 1.1030155431619437 1.209401794333979 1.0 13.911780478951208 -6.273373480650628 22.631410264262197 1.1072155161906414 1.0413176345370947 0.25383161004996246 0.05201102164076917 279.3921010528775 529827.4805344162 0.01555010257044323 0.017804571042136397 5.328764401130089e-07 6.273373480650628 -0.06589788165354671 S(ph)SDELDAWTDFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSDELDAWTDFR 12 0 O43524;O43524-2 O43524 FOXO3 Forkhead box protein O3 1 S(0.95)S(0.05)DELDAWTDFR;S(0.948)S(0.052)DELDAWTDFR;S(0.984)S(0.016)DELDAWTDFR;S(0.948)S(0.052)DELDAWTDFR 177.36 8.3174e-05 6360920.0 17278.0 19893.2 19123.6 19042.6 25050.0 18151.85 20571.4 15558.8 16795.0 14952.4 True False 20202.824143944697 21868.065426421323 19579.579150656868 17975.704858942183 20141.632322929618 17199.93503149435 18622.728067961452 15150.39798591126 17040.59510198164 17663.15175686673 1.1437836475639545 1.2380613453043503 1.1084986088649273 1.017695205610966 1.1403192703193161 0.9737749676983725 1.0543264488865458 0.8577403508986662 0.9647539316054924 1.0 14.108455175440659 -6.1977657433390245 0.5801749905284466 0.941973635571495 1.2111113518265775 0.602393115116525 0.06593664819156726 0.7033672328351009 0.476027800857993 0.04719142579065771 0.10347162883041273 6.342117102055812e-07 6.1977657433390245 0.2691377162550824 S(ph)SDELDAWTDFR ddPTM_PC-9_Lapatinib_30min_R1 8 SSDELDAWTDFR 12 0 O43524;O43524-2 O43524 FOXO3 Forkhead box protein O3 1 S(0.778)S(0.222)DELDAWTDFR;S(0.935)S(0.065)DELDAWTDFR;S(0.973)S(0.027)DELDAWTDFR;S(0.77)S(0.23)DELDAWTDFR;S(0.995)S(0.005)DELDAWTDFR;S(0.999)S(0.001)DELDAWTDFR;S(0.994)S(0.006)DELDAWTDFR;S(0.975)S(0.025)DELDAWTDFR 198.74 9.5708e-47 4948780.0 19424.800000000003 21027.4 24238.899999999998 21093.519999999997 24402.5 20270.7 19086.5 21252.199999999997 25200.0 14336.210000000001 True False 19147.798789927954 20978.712347219607 22246.071206859775 22644.80782671996 22967.192927160908 19403.76941430963 20074.705579038247 22239.654796970488 22361.71063223572 16814.20479670093 1.1387870566251752 1.2476779366536432 1.323052233265567 1.3467665048996569 1.3659398826679712 1.1540105315070737 1.1939134691030437 1.3226706267627995 1.3299297173199205 1.0 14.037392929868952 -6.76765567084993 24.990188836722055 1.219884838379159 1.2880093055046515 0.12466101203522018 0.1052072161396932 412.1005486308403 1656676.4122922157 0.03752452597545268 0.03391343244714859 1.7074355879627746e-07 6.76765567084993 0.06812446712549258 S(ph)SDGGSEEPPDRR ddPTM_PC-9_AZD4547_30min_R2 1 SSDGGSEEPPDRR 13 1 Q9HCD6;Q9HCD6-2;Q9HCD6-3;Q9HCD6-4 Q9HCD6 TANC2 Protein TANC2 1 S(0.499)S(0.499)DGGS(0.001)EEPPDRR 101.72 0.0028372 3074900.0 6353.2 7033.8 9413.7 11157.0 8972.4 8734.9 8542.9 9750.4 8522.8 7739.1 True False 8373.385445230733 9307.338296544194 9288.868187197693 8584.926023931688 7726.737134897548 8188.705322160999 9303.201550209798 8243.699721902118 8973.297808358955 7468.156464598712 1.1212118392166899 1.246269857984866 1.2437966760913082 1.149537514998085 1.0346244312802744 1.0964828282559294 1.2457159399792637 1.1038466803661269 1.2015412171524609 1.0 12.866536438302258 -14.522878729276497 0.2584619482225959 2.6929591798001534e-10 1.1726638983381055 0.31286200944626297 0.06994283717510792 258.9347623946171 2.544113785030026 137.77853929688538 0.10066242744643371 3.0000001105506137e-15 14.522878729276497 1.1726638980688096 S(ph)SDGGSEEPPDRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSDGGSEEPPDRR 13 1 Q9HCD6;Q9HCD6-2;Q9HCD6-3;Q9HCD6-4 Q9HCD6 TANC2 Protein TANC2 1 S(0.5)S(0.5)DGGSEEPPDRR;S(0.5)S(0.5)DGGSEEPPDRR 201.0 4.4306999999999996e-07 5502800.0 9938.8 8015.9 14837.3 14543.3 17434.2 19315.2 21452.0 20749.5 20003.0 16841.1 True False 11621.242539752155 8811.665576762445 15191.077502773602 13728.48605101477 14018.093662451874 18302.27690953371 19419.91126096956 20204.84761091253 20295.506033041893 19894.258115925742 0.5841505861658205 0.4429250653839931 0.7635910529688387 0.6900727823584861 0.704630128993356 0.9199778550617266 0.9761565949234136 1.0156120169536835 1.020169031424949 1.0 14.280064479514435 -6.421358714977336 0.6454536961903176 1.0426884814631692 0.5119010631213894 0.8666475367833107 0.07077340190421202 0.2829107164822476 0.2579990117371213 0.050407247409011556 0.0788429824065342 3.790018108624492e-07 6.421358714977336 -0.5307874183417798 S(ph)SDGGSEEPPDRR ddPTM_PC-9_Lapatinib_30min_R1 2 SSDGGSEEPPDRR 13 1 Q9HCD6;Q9HCD6-2;Q9HCD6-3;Q9HCD6-4 Q9HCD6 TANC2 Protein TANC2 1 S(0.498)S(0.498)DGGS(0.003)EEPPDRR;S(0.5)S(0.5)DGGSEEPPDRR 150.14 0.00018495 4304200.0 10336.9 10188.3 11340.900000000001 11832.1 13953.8 16678.7 16046.0 14525.0 15688.6 19791.4 True False 10189.4939104447 10164.709617317283 10408.494979139985 12702.272104728521 13133.064918226315 15965.390880948667 16876.783366319007 15199.884526119478 13921.584659717997 23212.317119617175 0.43896927040658784 0.4379015487741589 0.44840396266788746 0.5472212032633996 0.5657800059575832 0.6877982408510183 0.7270615544044982 0.6548197858831493 0.599749890886705 1.0 14.502602923348887 -9.876361498151196 0.0865391829672618 1.6793953118382947 3.1775296560390965e-16 0.8708011548957968 0.05849566746105876 19.21465462892258 0.4347929720201561 5.776467607359818 2.7353021131225135 1.3293474347709974e-10 9.876361498151196 -1.6793953118382945 S(ph)SDGSLSHEEDLAK ddPTM_PC-9_AZD4547_30min_R2 1 SSDGSLSHEEDLAK 14 0 A0A2R8Y7R9;Q13136-2;Q13136;E9PJZ7;H0YEF9 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 S(0.927)S(0.072)DGS(0.001)LSHEEDLAK 241.76 9.564499999999999e-28 5530100.0 27447.0 22073.0 45057.0 67413.0 57383.0 52530.0 36138.0 56368.0 44280.0 51415.0 True False 36174.57506693444 29207.66558895901 44459.51474027919 51871.974370467586 49416.360952679956 49245.290795901165 39354.211991417644 47657.62080778003 46620.55040058832 49614.97649950801 0.7291059599170253 0.5886864743198787 0.8960906137024989 1.0454902537539639 0.9959968630272348 0.9925489090252716 0.7931921925188836 0.9605490956597069 0.9396467294719089 1.0 15.598488049763011 -5.372257588261306 4.864744566895571 0.9559504017793042 0.6610080902936822 0.7363980208256765 0.07102792724065572 0.10711025281163138 3.8413296511091795 0.01943791803100207 0.042165091543361136 4.243677887353105e-06 5.372257588261306 -0.294942311485622 S(ph)SDGSLSHEEDLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSDGSLSHEEDLAK 14 0 A0A2R8Y7R9;Q13136-2;Q13136;E9PJZ7;H0YEF9 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 S(0.349)S(0.349)DGS(0.298)LS(0.003)HEEDLAK 95.751 0.0017682000000000002 7496000.0 36547.0 43751.0 55654.0 71586.0 87773.0 77996.0 93384.0 77338.0 67200.0 54495.0 True False 42733.68526384693 48094.31013971405 56981.00242897039 67575.26850494333 70574.51073375251 73905.75245588925 84537.99147838794 75307.95944638454 68182.67287009025 64374.51211781734 0.6638292681059288 0.7471017419393021 0.8851484936256222 1.0497208643891236 1.0963113880317727 1.1480592244431764 1.3132214706911902 1.1698412456867548 1.0591563435122158 1.0 15.9742019728628 -5.545439102746491 1.1504298819183665 1.1565447874800836 0.6430537062669667 0.8283717223341258 0.07778430824388377 0.23769937366464186 0.5533447652931854 0.027682527033195424 0.10737093234384211 2.8481371411211205e-06 5.545439102746491 -0.5134910812131169 S(ph)SDGSLSHEEDLAK ddPTM_PC-9_Lapatinib_30min_R1 2 SSDGSLSHEEDLAK 14 0 A0A2R8Y7R9;Q13136-2;Q13136;E9PJZ7;H0YEF9 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 S(0.333)S(0.333)DGS(0.333)LS(0.001)HEEDLAK;S(0.996)S(0.004)DGSLSHEEDLAK 284.91 1.1795999999999996e-83 12578300.0 87806.0 65281.0 95757.0 71163.0 103193.0 99834.0 78400.0 88627.0 116670.0 80089.0 True False 86553.87033835158 65129.845855352716 87884.22909270953 76396.56441280898 97123.39062524389 95564.33254442067 82459.16838585392 92744.93396877042 103529.39601043414 93932.27693811564 0.9214497205829995 0.6933702448015977 0.9356126771057549 0.8133153682960382 1.0339724937066161 1.0173748115078725 0.877857655257091 0.9873595849259839 1.1021706210596947 1.0 16.51933336040176 -6.258560760520563 24.96213296123304 0.9969398793471635 0.8371590627592917 0.490851662897863 0.08073785557441708 221.26988183287958 1918754.337273287 0.02400612853783242 0.02963614138305967 5.513650575573474e-07 6.258560760520563 -0.1597808165878718 S(ph)SDIVSSVR ddPTM_PC-9_AZD4547_30min_R2 4 SSDIVSSVR 9 0 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 S(0.964)S(0.02)DIVS(0.006)S(0.01)VR;S(0.965)S(0.035)DIVSSVR;S(0.955)S(0.045)DIVSSVR;S(0.957)S(0.043)DIVSSVR 146.71 0.00042235 90714000.0 50079.8 51633.2 73519.0 95930.0 81826.0 72211.0 80744.0 107438.0 68961.0 69453.0 True False 66004.13467544958 68322.62215774196 72544.09002353881 73814.82060372557 70465.87231957194 67695.63475467001 87930.05957814575 90835.9257796314 72606.13767332828 67021.47160984785 0.9848207311782036 1.0194139358125185 1.0824007333924235 1.1013607852931646 1.0513924959716638 1.0100589128920754 1.311968500035527 1.3553257425980536 1.0833265210288197 1.0 16.03233574411214 -7.248907277420148 24.909266175704808 1.2172656719099013 1.0455868465241076 0.3154646753123683 0.1016428875252487 735.6317655779254 1462170.8816983087 0.038308910177474405 0.029465856505853733 5.6375800623133437e-08 7.248907277420148 -0.1716788253857937 S(ph)SDIVSSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSDIVSSVR 9 0 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 S(0.963)S(0.037)DIVSSVR;S(0.974)S(0.026)DIVSSVR;S(0.967)S(0.033)DIVSSVR;S(0.966)S(0.034)DIVSSVR 175.49 0.00010686 74704000.0 53070.0 55189.0 58255.0 56359.8 67368.0 57695.0 52492.0 59583.0 53548.0 42560.5 True False 62053.70281972138 60667.79918860543 59644.02013331781 53202.14312693696 54167.72400523446 54669.37263375725 47519.577750830416 58019.009383406876 54331.03819713679 50276.3817412674 1.234251564463459 1.2066858649616912 1.186322843204155 1.0581935549922052 1.0773990118062333 1.0873768306378346 0.9451670168982313 1.154001289949317 1.080647340071835 1.0 15.61759320608269 -5.692661633057931 3.5377487193229444 1.0605546071337608 1.2163410981912757 0.6374081653884414 0.05264942980338793 0.15065297702728328 3.7479081170953057 0.014841101661081475 0.02664346041095434 2.0292631405864643e-06 5.692661633057931 0.15578649105751485 S(ph)SDIVSSVR ddPTM_PC-9_Lapatinib_30min_R1 4 SSDIVSSVR 9 0 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 S(0.987)S(0.013)DIVSSVR;S(0.953)S(0.047)DIVSSVR;S(0.972)S(0.028)DIVSSVR;S(0.964)S(0.036)DIVSSVR 150.04 0.00023698 81934000.0 85555.0 96866.0 97440.0 79708.0 103090.0 100504.0 98375.0 89107.0 106815.0 105181.0 True False 84334.97001113463 96641.71272842916 89428.85932927705 85569.99221809322 97026.44888273807 96205.67820626705 103468.3761474281 93247.2365210964 94784.3698881848 123361.39570512742 0.6836415033169839 0.7834032046737968 0.7249339132238759 0.6936529189620426 0.7865219773831178 0.7798685938689355 0.8387419383187761 0.7558866855234572 0.7683470938894797 1.0 16.912531467479724 -14.522878744918597 0.18197176440570192 1.9931664464798577 0.7109212934316453 0.7867207773631772 0.03928811707559979 62.355882479913646 0.6006010994480029 22.388479715183305 0.1228123783076212 3.0000000024988185e-15 14.522878744918597 -1.2822451530482124 S(ph)SDKLNLVTK ddPTM_PC-9_AZD4547_30min_R2 2 SSDKLNLVTK 10 1 A0A088AWN2;Q8TBZ3-4;Q8TBZ3-5;Q8TBZ3-6;Q8TBZ3;Q8TBZ3-2;Q8TBZ3-7 A0A088AWN2 WDR20 WD repeat-containing protein 20 1 S(0.584)S(0.416)DKLNLVTK;S(0.974)S(0.026)DKLNLVTK 98.94200000000001 0.0059995 51966000.0 267276.0 290032.0 309271.0 446903.0 445238.0 398997.0 422531.0 462464.0 428708.0 409030.0 True False 352264.20831384003 383779.1721151164 305169.86446591857 343876.41793252144 383424.3890673079 374047.6545153668 460135.4404489917 391000.81516550534 451368.62965527107 394709.9841990424 0.8924633842963597 0.9723067251361601 0.7731495951012707 0.8712128694447039 0.9714078802576135 0.9476518696997134 1.1657557671937604 0.9906027990625477 1.143545001961889 1.0 18.590433487136963 -6.826073569408773 1.7669494222242796 1.0724362567328842 0.8812693774670679 0.5658612178763284 0.07358127730928285 0.2548222204834447 1.64093155041309 0.03086739433927454 0.026850993929716953 1.4925415518864633e-07 6.826073569408773 -0.19116687926581633 S(ph)SDKLNLVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSDKLNLVTK 10 1 A0A088AWN2;Q8TBZ3-4;Q8TBZ3-5;Q8TBZ3-6;Q8TBZ3;Q8TBZ3-2;Q8TBZ3-7 A0A088AWN2 WDR20 WD repeat-containing protein 20 1 S(0.956)S(0.044)DKLNLVTK 68.46300000000001 0.019308000000000002 18418000.0 33773.0 48682.0 57181.0 87445.0 84792.0 86302.0 83228.0 84463.0 85106.0 62258.0 True False 39490.10185284435 53514.82723187034 58544.41190015009 82545.74015051499 68177.61628446516 81776.17119401188 75344.04132146071 82245.93574594588 86350.51424526641 73544.88256594317 0.5369524088564015 0.7276485509904361 0.7960365134536304 1.1223859127995928 0.9270205336630252 1.1119219766336321 1.024463411902308 1.1183094306011163 1.1741199554957644 1.0 16.16633733824791 -5.085052771024043 0.8466728621378496 1.0865383531866888 0.36916415341306225 0.8407237147739695 0.07847746706960022 0.5800122288821363 0.4368463651823849 0.028949995931020312 0.35651035656923846 8.22142745498882e-06 5.085052771024043 -0.7173741997736265 S(ph)SDPLDSGTR ddPTM_PC-9_AZD4547_30min_R2 1 SSDPLDSGTR 10 0 E7ER60;A0A1W2PR85;O15056-2;O15056 E7ER60 SYNJ2 Synaptojanin-2 1 S(0.979)S(0.021)DPLDSGTR 103.21 0.0029170000000000003 10395000.0 24924.0 45381.0 66498.0 73844.0 62889.0 56500.0 63225.0 82873.0 73696.0 66177.0 True False 32849.31354859453 60049.520776176774 65616.1930709786 56820.406678427134 54157.947893158074 52967.04606831178 68851.90251694575 70066.88208208818 77591.42010663418 63860.16337271118 0.5143944489598934 0.940328329974759 1.0274980458164285 0.8897629394839243 0.8480709261119888 0.8294223389185024 1.0781667142800897 1.0971923399749595 1.2150206953556066 1.0 15.962628623292074 -7.317234951003377 4.830121188677001 1.110389500638216 0.8567932122272995 0.46517724494869817 0.13382783580566115 0.21065468249515298 10.574207419557704 0.058226234027012345 0.0391126709693666 4.816871369459347e-08 7.317234951003377 -0.2535962884109165 S(ph)SDPLDSGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSDPLDSGTR 10 0 E7ER60;A0A1W2PR85;O15056-2;O15056 E7ER60 SYNJ2 Synaptojanin-2 1 S(0.949)S(0.051)DPLDSGTR;S(0.973)S(0.026)DPLDSGTR 89.561 0.009270700000000002 14536600.0 65198.0 87262.0 92263.0 134894.0 128727.0 121577.0 119694.0 114150.0 122291.0 99142.0 True False 76234.73368080262 95924.79466553305 94462.89982937592 127336.32651224872 103503.86842450128 115201.28809592336 108355.71781048363 111153.68345192252 124079.27452315784 117115.65979235976 0.6509354412207813 0.8190603616596016 0.8065778735043114 1.0872698556111942 0.8837747967095818 0.9836540075013838 0.9252026415817742 0.9490932608755522 1.059459296418124 1.0 16.837574469099835 -4.998472772682943 1.120394570211844 0.9753704142494652 0.5796444191196365 0.6963061048252152 0.06869625475835771 0.6609816661078018 0.8914393209904917 0.021231472886390046 0.283232563119455 1.0035227612433414e-05 4.998472772682943 -0.39572599512982876 S(ph)SDPLDSGTR ddPTM_PC-9_Lapatinib_30min_R1 2 SSDPLDSGTR 10 0 E7ER60;A0A1W2PR85;O15056-2;O15056 E7ER60 SYNJ2 Synaptojanin-2 1 S(0.74)S(0.259)DPLDSGT(0.001)R;S(0.969)S(0.028)DPLDS(0.002)GT(0.001)R 83.226 0.013835 17950100.0 124302.0 111172.0 138162.0 104741.0 120446.0 110600.0 91820.0 85312.0 116412.0 76321.0 True False 122529.43068580507 110914.5880643871 126802.85368074311 112444.00254573324 113361.60308594714 105869.89582119253 96573.99032128952 89275.90696676802 103300.4546872946 89512.98315865973 1.368845349155937 1.2390893940803371 1.4165861666791724 1.256175345496293 1.2664263784507803 1.1827322929629163 1.078882491829306 0.9973514882028733 1.1540276174708297 1.0 16.44980932874393 -6.9178239600673805 1.308258272008788 1.0478652037385372 1.324283610304431 0.7909050854480179 0.06177412202999387 0.18720267616186892 0.6625453083766042 0.030724723157372253 0.024061075201810993 1.208303517969372e-07 6.9178239600673805 0.2764184065658939 S(ph)SDPLGDTASNLGSAVDELMR ddPTM_PC-9_AZD4547_30min_R2 6 SSDPLGDTASNLGSAVDELMR 21 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 S(0.785)S(0.215)DPLGDTASNLGSAVDELMR;S(0.806)S(0.189)DPLGDT(0.002)AS(0.002)NLGSAVDELMR;S(0.772)S(0.227)DPLGDTASNLGSAVDELMR;S(0.77)S(0.228)DPLGDT(0.001)AS(0.001)NLGSAVDELMR;S(0.789)S(0.209)DPLGDT(0.001)ASNLGSAVDELMR;S(0.82)S(0.18)DPLGDTASNLGSAVDELMR 145.73 3.9929e-06 38454600.0 68705.79999999999 66041.9 91972.6 114826.0 97697.7 90925.20000000001 81571.0 97863.2 90539.79999999999 93943.5 True False 90552.81523058219 87388.65265525632 90752.98323017063 88354.6397440153 84134.06074005633 85239.63287027375 88830.66097603449 82740.6911126162 95325.54898733478 90654.56665917583 0.9988775918043248 0.9639740817889735 1.0010856217686728 0.9746297732158676 0.9280730562241399 0.9402684940378125 0.97988070816114 0.9127029576313285 1.0515250637700353 1.0 16.468092076083728 -8.27567530741831 24.999373490002622 1.0257625333155025 0.9628796183616598 0.42295451404593243 0.029583322791857252 900.170450640785 1580751.6661052317 0.027991583828673266 0.00736776354099381 5.300595854552585e-09 8.27567530741831 -0.06288291495384268 S(ph)SDPLGDTASNLGSAVDELMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SSDPLGDTASNLGSAVDELMR 21 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 S(0.821)S(0.179)DPLGDTASNLGSAVDELMR;S(0.793)S(0.207)DPLGDTASNLGSAVDELMR;S(0.788)S(0.212)DPLGDTASNLGSAVDELMR;S(0.801)S(0.199)DPLGDTASNLGSAVDELMR;S(0.794)S(0.206)DPLGDTASNLGSAVDELMR;S(0.824)S(0.176)DPLGDTASNLGSAVDELMR 143.14 8.4541e-11 28753200.0 81623.2 94009.1 94566.9 100197.4 113636.2 86194.8 97943.1 89545.9 88088.3 73395.5 True False 95440.39562831525 103341.70216350241 96821.7335429656 94583.66452235357 91370.0023542872 81674.59295072666 88665.22052136248 87195.41500672356 89376.4247408092 86701.52315154149 1.1007926061633253 1.1919248752167404 1.116724712825811 1.090911221444579 1.053845411626574 0.9420202780979002 1.0226489373939687 1.0056964611142853 1.0308518407986025 1.0 16.403769718139273 -6.163322780901937 1.7441574775428996 1.0024237250185213 1.1432624460353369 0.7679068872996678 0.03260109557993682 0.16294435391367298 0.9814039690663666 0.01116305395107031 0.016061713245377314 6.865579795171662e-07 6.163322780901937 0.1408387210168156 S(ph)SDPLGDTASNLGSAVDELMR ddPTM_PC-9_Lapatinib_30min_R1 7 SSDPLGDTASNLGSAVDELMR 21 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 S(0.931)S(0.067)DPLGDT(0.001)AS(0.001)NLGSAVDELMR;S(0.513)S(0.169)DPLGDT(0.278)AS(0.029)NLGS(0.011)AVDELMR;S(0.809)S(0.191)DPLGDTASNLGSAVDELMR;S(0.779)S(0.22)DPLGDTASNLGSAVDELMR;S(0.833)S(0.167)DPLGDTASNLGSAVDELMR;S(0.815)S(0.185)DPLGDTASNLGSAVDELMR;S(0.5)S(0.5)DPLGDTASNLGSAVDELMR 165.49 2.2384e-08 31497000.0 86732.1 88960.5 95644.0 75571.3 87575.7 88656.0 71712.0 73858.2 99208.8 67719.6 True False 85495.28434928066 88754.51742796676 87780.5195165168 81129.06550046666 82424.66950645068 84864.38954722993 75424.89647048917 77289.92160461511 88034.86022902165 79424.84262930497 1.0764300125630455 1.1174654489679714 1.105202309637676 1.021457050649955 1.0377693776636943 1.0684867194929506 0.9496386013947233 0.973120236011621 1.1084045912423361 1.0 16.27730270596576 -5.763249220432295 24.5692474370765 1.0210685173884229 1.1014758908918627 0.39665944015047716 0.043470849111306276 37.86937121797407 514105.14519940387 0.012345229176717192 0.01943150370608722 1.7248478018640673e-06 5.763249220432295 0.08040737350343985 S(ph)SDPWSNSHFPHEN ddPTM_PC-9_AZD4547_30min_R2 1 SSDPWSNSHFPHEN 14 0 Q92545 Q92545 TMEM131 Transmembrane protein 131 1 S(0.796)S(0.204)DPWSNSHFPHEN 87.419 0.0034665 2910900.0 10495.0 12943.0 31074.0 36388.0 27449.0 27271.0 22469.0 33262.0 24703.0 25046.0 True False 13832.191690438922 17126.57163584001 30661.938456609092 27999.3087889958 23638.180154228812 25565.740058919124 24468.69747177939 28122.122184721455 26008.75014782598 24169.147163409078 0.5723078103219211 0.708612989943179 1.268639652417268 1.158473180691514 0.978031206248596 1.0577841198147206 1.0123939130472843 1.163554592745291 1.076113690399551 1.0 14.560878946371277 -5.11730156790089 5.041058400605932 1.0887464074945894 0.6035262416838502 0.8194166192297991 0.08516266576760011 0.08297161645512342 3.0167240565357636 0.0226613038741018 0.06506259986398807 7.633055709991895e-06 5.11730156790089 -0.48522016581073923 S(ph)SDPWSNSHFPHEN ddPTM_PC-9_Lapatinib_30min_R1 2 SSDPWSNSHFPHEN 14 0 Q92545 Q92545 TMEM131 Transmembrane protein 131 1 S(0.493)S(0.493)DPWS(0.013)NS(0.001)HFPHEN;S(0.5)S(0.5)DPWSNSHFPHEN 128.76 1.3983e-05 1904300.0 39467.0 34589.0 32735.0 18663.1 32833.0 37753.0 42368.0 43410.0 61754.0 41797.0 True False 38904.19334263863 34508.91129564181 30043.6546607542 20035.646632276515 30901.82749216164 36138.39219654138 44561.60773178386 45426.98707599628 54798.61422155098 49021.55575899829 0.7936140079662294 0.7039538170778562 0.6128662013187831 0.4087109501537763 0.6303722314339109 0.7371939065786972 0.9090206755342363 0.9266737126688966 1.1178473096805432 1.0 15.581128650171491 -7.3296064145519155 1.5542733863974745 1.028571551626038 0.6213605161075313 0.7515125206348845 0.09926200031061856 0.21625869315752455 1.014613734654355 0.06519313909618077 0.03691817177262755 4.6815922493738035e-08 7.3296064145519155 -0.4072110355185068 S(ph)SDSYPLAPVR ddPTM_PC-9_AZD4547_30min_R2 2 SSDSYPLAPVR 11 0 Q52LW3 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 S(0.984)S(0.016)DSYPLAPVR;S(0.942)S(0.053)DS(0.005)YPLAPVR 151.98 0.0003768 12492700.0 14726.5 16204.2 23623.0 37918.0 30919.0 26596.0 18681.7 30739.0 28210.0 24199.2 True False 19409.220669771214 21441.890759598144 23309.74358500599 29176.590927260168 26626.430550788773 24932.947915625115 20344.33510875164 25988.993861949177 29701.12300814355 23351.993373663234 0.8311590517861852 0.918203873069811 0.9981907416646968 1.2494261393618762 1.140220884989566 1.0677010530392197 0.8712033608101447 1.1129239995100373 1.2718881224778424 1.0 14.511258086124718 -5.321561088435966 2.7436200590284208 1.097711030185264 0.8599905411227754 0.3997365751809895 0.11057170974559839 0.29665230951034993 4.314078826356405 0.03210422510303852 0.09058539579325516 4.769127262264419e-06 5.321561088435966 -0.23772048906248855 S(ph)SDSYPLAPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSDSYPLAPVR 11 0 Q52LW3 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 S(0.976)S(0.013)DS(0.011)YPLAPVR;S(0.989)S(0.01)DS(0.001)YPLAPVR 160.67 0.00010319 9676000.0 19699.7 26572.0 25536.0 25256.0 39109.0 33448.0 35491.0 30845.0 27907.1 25964.9 True False 23034.470123189454 29209.89255176983 26144.87508581928 23840.98820105678 31445.872196305576 31693.92799816121 32129.035547411466 30035.35143297896 28315.188542453798 30672.130831964696 0.7509902148429897 0.9523268113257065 0.8523983947855565 0.7772850321899091 1.025226201876217 1.0333135370279412 1.0474992990682104 0.979239153534057 0.9231568780655229 1.0 14.904640775496532 -6.271449605655472 24.821537568131326 1.0042678666694844 0.8431233255217647 0.6569360132163151 0.05933812442414599 411.06838747641535 1019291.0072057286 0.018691652281264275 0.0214501214461595 5.352422582165507e-07 6.271449605655472 -0.1611445411477197 S(ph)SDSYPLAPVR ddPTM_PC-9_Lapatinib_30min_R1 2 SSDSYPLAPVR 11 0 Q52LW3 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 S(0.942)S(0.01)DS(0.04)Y(0.009)PLAPVR;S(0.993)S(0.006)DSYPLAPVR 164.04 0.0016177 10579600.0 15634.5 18330.0 16450.4 18439.1 16200.8 18923.8 14661.300000000001 12681.3 21375.1 20151.0 True False 15411.549162983845 18287.558011191843 15097.911612380349 19795.17292503441 15247.900795998285 18114.47318753239 15420.39037570815 13270.519493361706 18967.61114821833 23634.0735004803 0.6520902612353577 0.773779349159602 0.6388196944582374 0.8375692376784784 0.6451660055846239 0.7664558201176899 0.6524643487884039 0.5614994593755502 0.8025536159829944 1.0 14.528580689032903 -8.5344397546878 23.059177832940666 1.0000000038944152 0.6956824939823072 0.6050444557799513 0.0766800506608698 398.5014919978517 794837.7381508817 0.07143916230217 0.018445512388384218 2.921192959865967e-09 8.5344397546878 -0.30431750991210804 S(ph)SDTEEESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSDTEEESR 9 0 C9J8Q2;C9JVB3;F8WDM0;C9J367;C9J713;Q96IZ7-2;Q96IZ7 C9J8Q2 RSRC1 Serine/Arginine-related protein 53 1 S(0.499)S(0.499)DT(0.001)EEESR 92.611 0.0068949 1287400.0 665.01 2260.7 3820.6 672.05 5015.4 5699.7 2415.6 3015.9 3901.9 6095.0 True False 777.5830584537947 2485.1273555541948 3911.6975937061893 634.3972173154971 4032.668373350145 5400.797698251602 2186.776880570485 2936.735820610188 3958.957905830435 7199.975252006548 0.10799801822056146 0.34515776354392597 0.5432931998781587 0.08811102748425394 0.560094754801593 0.750113369729495 0.3037200551433918 0.4078813770633107 0.5498571546794025 1.0 12.813776232346372 -14.522878745268613 0.11968895070480913 2.885435543581404 0.12837214347405165 0.5411473501935683 0.17960532765664966 131.54083804111147 1.0177074529676493 60.247407491667005 1.8166004799910638 3.0000000000809875e-15 14.522878745268613 -2.7570634001073526 S(ph)SDTEENVK ddPTM_PC-9_AZD4547_30min_R2 1 SSDTEENVK 9 0 H0YBT0;A0A087WUS5;P01106;P01106-2;A0A494C1T8 H0YBT0 MYC Myc proto-oncogene protein 1 S(0.688)S(0.312)DTEENVK 108.9 0.0024154 0.0 24440.0 21266.0 22287.0 18800.0 25819.0 27465.0 21889.0 22779.0 30972.0 32921.0 True False 32211.41161641995 28139.818620704154 21991.459817932897 14465.950457104578 22234.477518380787 25747.60920825104 23837.078595388262 19259.028959346113 32609.116689408802 31768.445810372526 1.0139435781243915 0.8857788885446952 0.6922422314645496 0.4553559385137244 0.6998918880419747 0.8104774581022891 0.7503382046976109 0.6062313867761816 1.0264624490620122 1.0 14.95530689117735 -8.277206003873776 24.19849795100992 1.0132313682198955 0.734562112873101 0.36937399110303293 0.14307360133386335 702.3652490953465 1077969.3665395295 0.14687574286935148 0.038505107485061585 5.281946477294549e-09 8.277206003873776 -0.27866925534679443 S(ph)SDTEENVK ddPTM_PC-9_Lapatinib_30min_R1 2 SSDTEENVK 9 0 H0YBT0;A0A087WUS5;P01106;P01106-2;A0A494C1T8 H0YBT0 MYC Myc proto-oncogene protein 1 S(0.932)S(0.068)DTEENVK;S(0.917)S(0.083)DTEENVK 136.02 0.0010253 10306200.0 41617.0 56753.0 42008.0 42845.0 59370.0 42278.0 59350.0 57606.0 54113.0 55324.0 True False 41023.533948376906 56621.59191539395 38554.26439556934 45995.96422673014 55877.973325911 40469.868494831586 62422.852598219695 60282.58506104219 48018.22410484807 64886.679685403804 0.6322335207668995 0.8726227353582853 0.5941784135433591 0.7088660484669073 0.8611624696598661 0.6237007147082492 0.9620287692461733 0.9290440711917441 0.7400320734187563 1.0 15.985634723348896 -7.269281963489185 24.95891328691277 0.9018632371595133 0.723414607168474 0.4308172747799134 0.10797541382100556 612.3015938876619 1948632.2741088825 0.04307486150707813 0.029645125989981053 5.3792042701156704e-08 7.269281963489185 -0.17844862999103928 S(ph)SECLDGTLTPSDGQSMER ddPTM_PC-9_AZD4547_30min_R2 1 SSECLDGTLTPSDGQSMER 19 0 A0A0A0MSQ9;Q86VX9-5;Q86VX9;Q86VX9-3;Q86VX9-2;Q86VX9-4 A0A0A0MSQ9 MON1A Vacuolar fusion protein MON1 homolog A 1 S(0.874)S(0.126)ECLDGTLTPSDGQSMER 129.05 4.6412e-06 0.0 4561.2 3177.8 3646.4 3350.7 4267.3 4987.6 3566.2 5417.7 3811.0 3650.2 True False 6011.566721146264 4204.96170473402 3598.0463534845653 2578.2478827989517 3674.859053959734 4675.724583545342 3883.584891355185 4580.518951360876 4012.4416796892983 3522.407609034412 1.7066641310129915 1.193774875442855 1.0214735921692175 0.7319561416419151 1.0432804666144566 1.3274229170845693 1.102537049203054 1.3003943494820354 1.1391190699787348 1.0 11.782346150533847 -4.771099992884002 3.482716863871712 1.08996661862007 1.7898466029260092 0.5839811835033641 0.15706455453518822 0.2413547824447403 4.742596776525412 0.04401397926748275 0.4568787347324032 1.6939477374193887e-05 4.771099992884002 0.6998799843059391 S(ph)SEDLAGPLPSSVSSSSTTSSKPK ddPTM_PC-9_AZD4547_30min_R2 2 SSEDLAGPLPSSVSSSSTTSSKPK 24 1 Q9NRF2-2;Q9NRF2-3;Q9NRF2 Q9NRF2-2 SH2B1 SH2B adapter protein 1 1 S(0.818)S(0.182)EDLAGPLPSSVSSSSTTSSKPK;S(0.79)S(0.21)EDLAGPLPSSVSSSSTTSSKPK 144.45 1.0233e-06 143265000.0 49215.0 67240.0 75812.0 80071.0 86983.0 85577.0 88405.0 107858.0 86100.0 94740.0 True False 64864.34626440703 88974.01505013385 74806.68334531912 61611.868034618084 74906.9118858716 80225.85666173295 96272.87373682228 91191.02443027121 90651.07022336623 91423.1814366119 0.7094956141881871 0.9732106633351391 0.8182463371960665 0.6739195362320284 0.8193426514894164 0.8775220398270366 1.0530466367938955 0.9974606330397541 0.9915545357193567 1.0 16.480272403730524 -7.051507777267402 3.234507426451 1.0097814259888316 0.8038285877773009 0.6311057167250638 0.07610758667651916 0.17953752684130297 3.744692236227906 0.03178117074566002 0.024956101684301502 8.881620711303474e-08 7.051507777267402 -0.20595283821153065 S(ph)SEDLAGPLPSSVSSSSTTSSKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSEDLAGPLPSSVSSSSTTSSKPK 24 1 Q9NRF2-2;Q9NRF2-3;Q9NRF2 Q9NRF2-2 SH2B1 SH2B adapter protein 1 1 S(0.817)S(0.183)EDLAGPLPSSVSSSSTTSSKPK;S(0.5)S(0.5)EDLAGPLPSSVSSSSTTSSKPK;S(0.802)S(0.198)EDLAGPLPSSVSSSSTTSSKPK;S(0.8)S(0.2)EDLAGPLPSSVSSSSTTSSKPK 163.67 3.9810000000000005e-10 112314000.0 127911.0 178587.8 194855.4 229467.9 264010.3 216830.6 249066.0 188478.7 201580.4 190712.8 True False 149563.8059425922 196316.81653834728 199501.49172922008 216611.5575079693 212279.37692879603 205459.621627544 225472.66539831465 183531.33383469013 204528.13199735046 225287.5209583062 0.663879673878039 0.8714056406820664 0.885541688596865 0.9614893740521804 0.9422598110442274 0.9119884703492664 1.0008218140055911 0.8146537946442943 0.9078538000123066 1.0 17.78140787700182 -4.388246926201656 1.4596672295021975 0.9270759727717042 0.24687448730824585 0.7014483163916381 0.051789816876903545 1.8150377179104027 1.6642316737867675 0.014554644159230275 2.377973098063041 4.0902803311171606e-05 4.388246926201656 -0.6802014854634584 S(ph)SEDLAGPLPSSVSSSSTTSSKPK ddPTM_PC-9_Lapatinib_30min_R1 3 SSEDLAGPLPSSVSSSSTTSSKPK 24 1 Q9NRF2-2;Q9NRF2-3;Q9NRF2 Q9NRF2-2 SH2B1 SH2B adapter protein 1 1 S(0.623)S(0.374)EDLAGPLPSSVSSSSTTSSKPK;S(0.963)S(0.037)EDLAGPLPSSVSSSSTTSSKPK;S(0.827)S(0.173)EDLAGPLPSSVSSSSTTSSKPK 171.87 5.6473999999999995e-11 202595400.0 77164.8 82203.1 66961.5 72641.3 102913.0 92998.2 83168.1 85572.7 99708.0 71905.1 True False 76064.41580170872 82012.76377249359 61456.18394886489 77983.58352627327 96859.8596747427 89020.88377539268 87474.13727336144 89548.72004050006 88477.8350682126 84333.80072747672 0.9019445957085418 0.9724779752013843 0.7287254151803206 0.9247013991255527 1.1485295200644843 1.055577751832414 1.0372369858680113 1.0618366451889827 1.0491384747869632 1.0 16.363823354350785 -6.0684434091089825 6.58012105588063 1.0594318770075015 0.8699232298843187 0.6392150619997057 0.06606399786802006 0.148906015354411 11.795515273203153 0.019488746183850613 0.025461588022668052 8.541941462273789e-07 6.0684434091089825 -0.18950864712318283 S(ph)SEGSLGGQNSGIGGR ddPTM_PC-9_Lapatinib_30min_R1 1 SSEGSLGGQNSGIGGR 16 0 C9JRJ5;Q9UGP4 C9JRJ5 LIMD1 LIM domain-containing protein 1 1 S(0.965)S(0.035)EGSLGGQNSGIGGR 124.04 3.6776e-05 4156300.0 5969.2 7757.2 6416.4 5964.8 5830.3 5749.3 8007.5 4554.2 8195.7 5521.3 True False 5884.078113382785 7739.238680000946 5888.86836002026 6403.471289989496 5487.373216810824 5503.415841272889 8422.089169001583 4765.804757924495 7272.613961452952 6475.6493483301965 0.9086468085088713 1.1951293628949469 0.9093865407549835 0.9888539273116583 0.8473857866046733 0.8498631635593416 1.3005783228786614 0.7359578169799141 1.1230709957030425 1.0 12.66080915153767 -5.35306490841705 24.99712960525052 0.9638546836761813 1.052091353979144 0.038876740671773824 0.1622232033328526 182.84193915314086 49872.645965980526 0.040280155422524104 0.08384989768508316 4.435423484005327e-06 5.35306490841705 0.08823667030296278 S(ph)SELLVR ddPTM_PC-9_AZD4547_30min_R2 4 SSELLVR 7 0 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 S(0.987)S(0.013)ELLVR;S(0.991)S(0.009)ELLVR;S(0.989)S(0.011)ELLVR;S(0.988)S(0.012)ELLVR 138.06 0.0031853000000000003 13654500.0 24444.1 36355.4 44707.6 67369.0 51492.4 50649.4 45040.5 63615.7 50813.3 52558.7 True False 32216.815331134636 48106.572081404505 44114.74801257311 51838.11789067438 44343.56908352262 47482.285011192034 49049.01724498993 53785.35530835742 53499.18730059205 50718.63591062318 0.6352066602876976 0.948498933728784 0.8697936610580872 1.022072399226666 0.8743052388409113 0.9361901036704876 0.9670807655676019 1.060465336708551 1.0548230712448334 1.0 15.630228323933641 -4.321936584135876 1.4531286765201274 0.9759986892171307 2.8639921977880938e-30 0.7133642628538033 0.06354991615240889 2.2818395383362957 1.7905685599352776 0.018833266848874097 4.486583077100135 4.765005605392955e-05 4.321936584135876 -0.9759986892171307 S(ph)SELLVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSELLVR 7 0 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 S(0.987)S(0.013)ELLVR;S(0.994)S(0.006)ELLVR 117.89 0.007162600000000001 6975700.0 12843.0 15245.8 19206.9 25796.0 30470.0 24763.0 29805.0 22130.1 22958.3 21547.2 True False 15017.066239187508 16759.30226801792 19664.86533857388 24350.73375176039 24499.62223072518 23464.384687229915 26981.654630486566 21549.208323779152 23294.021704663588 25453.536792458646 0.5899795522183288 0.6584272513744869 0.772578895377721 0.9566738779883432 0.962523300022648 0.9218516420154987 1.060035579750185 0.846609589051834 0.9151585453368163 1.0 14.635578513588136 -5.476140081295039 1.938729633605048 0.9512631690563081 0.605519885334303 0.854864045675223 0.05481171414201068 0.1255777888750643 0.9071819155832851 0.016207968205212395 0.04600723697231405 3.3408726309874965e-06 5.476140081295039 -0.34574328372200513 S(ph)SELLVR ddPTM_PC-9_Lapatinib_30min_R1 3 SSELLVR 7 0 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 S(0.987)S(0.013)ELLVR;S(0.99)S(0.01)ELLVR;S(0.99)S(0.01)ELLVR 129.42 0.0044245 9227100.0 31261.4 26657.9 29592.2 23350.9 26538.199999999997 31710.2 25618.4 27116.0 31771.2 23428.7 True False 30815.606703361354 26596.175270406482 27159.243545195353 25068.20308231888 24977.275252108648 30354.028666086608 26944.795400206105 28375.908351824808 28192.79289043205 27478.31957821957 1.121451645383259 0.9678967156160339 0.988388080569631 0.9122902516276489 0.908981176269114 1.104653746371974 0.980583813486311 1.0326653444381912 1.0260013466317934 1.0 14.746006159167719 -6.7546954502524965 24.99997069969247 1.0278101193026026 0.9758666104724495 0.13209126536423854 0.062342966836392295 338.04646358574223 1253148.4362397878 0.021208893054718216 0.0207564337156579 1.759156793230705e-07 6.7546954502524965 -0.051943508830153085 S(ph)SEMLVK ddPTM_PC-9_AZD4547_30min_R2 1 SSEMLVK 7 0 Q9H0B6;Q9H0B6-2;A8MZ87 Q9H0B6 KLC2 Kinesin light chain 2 1 S(0.985)S(0.015)EMLVK 78.149 0.028754000000000002 3032700.0 8101.5 9078.1 16062.0 20358.0 20886.0 20187.0 16236.0 22160.0 16410.0 18356.0 True False 10677.60847833168 12012.418293078828 15849.007385275645 15664.777627964628 17986.339418602627 18924.703698778943 17680.97254670035 18735.681186141173 17277.39909832102 17713.362027131574 0.6027996527128378 0.6781557490147492 0.8947486852580389 0.884348075987544 1.0154108176106227 1.0683857570229727 0.9981714662421729 1.05771457487538 0.9753879061387224 1.0 14.112550443674039 -5.22118339456133 0.9393992111011109 1.025214798648596 0.5017085827101365 0.9357857954606388 0.038147120277500314 0.25536296303843287 0.2806814764088483 0.013679505162775274 0.11842786973259802 6.009199264793504e-06 5.22118339456133 -0.5235062159384595 S(ph)SEMLVK ddPTM_PC-9_Lapatinib_30min_R1 2 SSEMLVK 7 0 Q9H0B6;Q9H0B6-2;A8MZ87 Q9H0B6 KLC2 Kinesin light chain 2 1 S(0.99)S(0.01)EMLVK;S(0.986)S(0.014)EMLVK 106.68 0.010019 8615700.0 35603.0 32136.0 39626.0 35493.0 40769.0 42160.0 35480.0 30868.0 40808.0 31963.0 True False 35095.29469120942 32061.591066429966 36368.10324078342 38103.27362117708 38371.04757493792 40356.915079760176 37316.980795026684 32302.239969174247 36211.77331270933 37487.761961979646 0.9361800452852671 0.8552548722152862 0.9701326869731036 1.0164190025486635 1.0235619724072647 1.0765357270644869 0.9954443488217256 0.8616742712444506 0.9659625279694095 1.0 15.194132078135388 -5.414404744988932 5.577190188858423 0.9908523813667971 0.8967803369551829 0.3224941895809085 0.0545874538875216 0.2838003107274817 12.200530211641723 0.01605827926736137 0.03404379957832152 3.8511927469258e-06 5.414404744988932 -0.09407204441161421 S(ph)SEPVVIMK ddPTM_PC-9_AZD4547_30min_R2 1 SSEPVVIMK 9 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(0.981)S(0.019)EPVVIMK 77.192 0.020621 6393400.0 45635.0 87224.0 85090.0 113810.0 70678.0 89765.0 57378.0 84358.0 76523.0 77087.0 True False 60145.98073303291 115417.45224171446 83961.65100318159 87572.86284697181 60865.57969108475 84151.98035968137 62484.5308440855 71322.40945399356 80567.8495551993 74388.2075934567 0.8085418734880695 1.551555763683527 1.1286957129286577 1.177241200992116 0.8182154357546125 1.1312543087418538 0.8399789814209979 0.9587865034170711 1.0830728708441977 1.0 16.182786315468086 -6.144006761244807 7.909658514463782 0.9714359066088516 1.193527988818934 0.19657622977017775 0.18984447928086123 0.4077088143513242 25.173268257239155 0.05298978437787172 0.06858567706466435 7.177831164916934e-07 6.144006761244807 0.22209208221008248 S(ph)SETLTFK ddPTM_PC-9_Lapatinib_30min_R1 1 SSETLTFK 8 0 Q9NPF5;Q5TG37;Q5TG36;Q5TG38;Q5TG39;Q5TG40 Q9NPF5 DMAP1 DNA methyltransferase 1-associated protein 1 1 S(0.95)S(0.049)ETLTFK 68.847 0.042479 3093400.0 15953.0 18579.0 15786.0 15023.0 21267.0 17786.0 17968.0 15908.0 18532.0 13372.0 True False 15725.507294578088 18535.981466990346 14488.136015722193 16127.841535258873 20016.11687253073 17025.334241191038 18898.29512190079 16647.143755009183 16444.73100938859 15683.332382929997 1.002689154997059 1.1818904945970041 0.92379193796156 1.028342774448413 1.2762668279808065 1.0855686677738017 1.2049923230900859 1.0614545014124814 1.0485482681784715 1.0 13.936944514355396 -4.684369130666891 21.802962883579674 1.0941557129609383 1.0026634572971276 0.06387741106185096 0.09929260242901997 52258.34262041184 14769736.297307674 0.024959396746195114 223.66500944372183 2.0683825698222664e-05 4.684369130666891 -0.0914922556638107 S(ph)SFMSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSFMSR 6 0 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5;B1AL79;A0A3B3IUG4 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 S(0.996)S(0.004)FMSR 122.18 0.016116 4222400.0 30447.0 34014.0 30925.0 28659.0 25109.0 24274.0 31732.0 35240.0 24080.0 28122.0 True False 30012.820196704033 33935.24267281392 28382.465873952136 30766.678463621392 23632.137986193342 23235.857605457724 33374.92769413154 36877.37904994493 21367.85682635859 32982.85022979043 0.909952293013057 1.0288753833094533 0.8605219280993739 0.9328083609897556 0.7164977502413835 0.7044830099149793 1.011887313000833 1.1180773884919422 0.6478474927875983 1.0 15.009428454938174 -10.2966575153493 15.234319245697522 0.9999998029341874 0.887235408926141 0.055130139119433874 0.14561968333078557 0.0 0.0 0.1438766007084878 0.034895201280936004 5.050594304518408e-11 10.2966575153493 -0.1127643940080465 S(ph)SFSEGQTLTVTSGAK ddPTM_PC-9_Lapatinib_30min_R1 1 SSFSEGQTLTVTSGAK 16 0 E9PEM3;H7C357;H0Y6E6;Q92622-3;Q92622-2;Q92622;H7C3H3 E9PEM3 KIAA0226 Run domain Beclin-1 interacting and cysteine-rich containing protein 1 S(0.636)S(0.358)FS(0.006)EGQTLTVTSGAK 131.56 7.0013e-05 0.0 11976.0 14033.0 13520.0 12219.0 16272.0 14680.0 13679.0 16436.0 18101.0 15327.0 True False 11805.220043870573 14000.507450684958 12408.437788709236 13117.626021389087 15314.912951982878 14052.170620751402 14387.231688138952 17199.67656256795 16062.274768019792 17976.251528056247 0.6567119972395635 0.7788335309412984 0.6902683670921547 0.7297197639294204 0.8519525290397882 0.7817074988531186 0.8003465942654524 0.9567999499630796 0.8935274822423775 1.0 14.133804595858848 -7.4007533995046515 0.39467250266832543 1.0096714659228794 0.6795712980098634 0.7970625507300653 0.04775381673915936 0.5275946600038032 0.20445662646435447 0.0545237675688255 0.05947776911342041 3.974171462717004e-08 7.4007533995046515 -0.330100167913016 S(ph)SFSQHAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSFSQHAR 8 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 S(0.716)S(0.283)FS(0.001)QHAR 64.10300000000001 0.03141 3104400.0 15442.0 15141.0 25842.0 18959.0 26736.0 24645.0 20019.0 19995.0 22492.0 17751.0 True False 18056.025606597643 16644.098416616987 26458.171286330748 17896.788695907322 21497.272725981882 23352.57281495705 18122.655394991114 19470.15243645371 22820.902949316514 20969.11578316131 0.8610771094648184 0.7937434553145339 1.2617685724057701 0.8534832312900319 1.0251873731006196 1.113665118569745 0.8642546296369841 0.9285156626436628 1.088310217049888 1.0 14.355978407309967 S(ph)SFSSDPDEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSFSSDPDEK 10 0 P46013 P46013 MKI67 Antigen KI-67 1 S(0.97)S(0.03)FSSDPDEK 139.76 0.00012173 7300100.0 29493.0 51508.0 36991.0 42080.0 53993.0 34646.0 69651.0 47868.0 39291.0 33659.0 True False 34485.58238669762 56621.373835487 37873.00572914872 39722.39402520067 43413.459241993565 32829.10276920275 63053.15305042847 46611.51572033836 39865.556543730876 39761.11025550262 0.8673194024285348 1.4240390540314716 0.9525137876125427 0.9990262789430888 1.0918573189486198 0.8256586035511788 1.5857996078392305 1.172289089032359 1.0026268453661653 1.0 15.279070421604187 S(ph)SFSSDPDEK ddPTM_PC-9_Lapatinib_30min_R1 2 SSFSSDPDEK 10 0 P46013 P46013 MKI67 Antigen KI-67 1 S(0.969)S(0.026)FS(0.003)S(0.002)DPDEK;S(1)SFSSDPDEK 271.21 6.7289e-48 13697000.0 61728.0 113392.0 103179.0 87011.0 117160.0 148296.0 224110.0 200256.0 142387.0 149187.0 True False 60847.74740047118 113129.4477907835 94696.02090245772 93410.07920018715 110268.87914542251 141953.72577486027 235713.31922134836 209560.6248304705 126349.87665841865 174973.77417081798 0.3477535287149297 0.6465508807070766 0.5412012248761967 0.5338518851916382 0.6302023241367167 0.8112857280901884 1.34713513689905 1.197668769640227 0.7221075115809624 1.0 17.41677917529976 -6.910168464029384 2.9421401493763084 1.0838958757413386 0.5407320715061501 0.6836800959803855 0.16811366974944786 0.14993309528911644 2.6188965315567136 0.06520527791233263 0.05574609611260098 1.229791638703653e-07 6.910168464029384 -0.5431638042351885 S(ph)SFSSDPDEKAQDSK ddPTM_PC-9_AZD4547_30min_R2 2 SSFSSDPDEKAQDSK 15 1 P46013 P46013 MKI67 Antigen KI-67 1 S(0.478)S(0.478)FS(0.026)S(0.019)DPDEKAQDSK;S(0.5)S(0.5)FSSDPDEKAQDSK 67.994 0.01354 21310000.0 117807.0 135971.0 143405.0 214491.0 181689.0 148692.0 104991.0 128161.0 115143.0 149783.0 True False 155267.17546217612 179920.9666921737 141503.35600083764 165043.41380291557 156464.61853042664 139394.26573432592 114334.99560548236 108356.66229679756 121229.22391090664 144539.14276039705 1.0742223351882123 1.2447906031269966 0.9789967845278297 1.1418596419691551 1.0825068942729132 0.9644049568316604 0.7910313664653166 0.7496700217491998 0.8387293683612658 1.0 17.14110071746819 -6.954819543857461 2.5696795560153727 0.8248576298832443 1.1096291926260986 0.6595698162778756 0.08744611611856337 0.1572356917550992 2.1033210431287306 0.03423532569779151 0.028174080792680575 1.1096357904921849e-07 6.954819543857461 0.2847715627428543 S(ph)SFYVNGLTLGGQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSFYVNGLTLGGQK 14 0 P07737;K7EJ44;I3L3D5 P07737 PFN1 Profilin-1 1 S(0.692)S(0.17)FY(0.133)VNGLT(0.005)LGGQK 81.128 0.010785 3013700.0 9153.8 11378.0 8284.0 10230.0 14505.0 11008.0 12303.0 10009.0 10473.0 10739.0 True False 10703.357544208888 12507.532645417616 8481.52197724495 9656.846266107488 11662.849375013731 10430.72110152352 11137.570773993497 9746.274355412106 10626.147812030578 12685.895690122774 0.843721074621677 0.9859400511353699 0.6685788835429772 0.7612269958696176 0.9193556103487761 0.8222297704721686 0.8779491055302622 0.7682764066080526 0.8376348088928468 1.0 13.630937764310303 -6.255625222852819 24.90073390825124 0.8572396188398395 0.8166371452585538 0.06742092151691703 0.09411739828450116 1890.1021471991507 8094880.737259223 0.028732146507948923 0.03614811532353474 5.551045372681893e-07 6.255625222852819 -0.04060247358128566 S(ph)SFYVNGLTLGGQK ddPTM_PC-9_Lapatinib_30min_R1 3 SSFYVNGLTLGGQK 14 0 P07737;K7EJ44;I3L3D5 P07737 PFN1 Profilin-1 1 S(0.964)S(0.036)FYVNGLTLGGQK;S(0.988)S(0.012)FYVNGLT(0.001)LGGQK;S(0.658)S(0.342)FYVNGLTLGGQK 154.81 3.0659000000000003e-09 11392500.0 65474.0 66961.0 67676.0 50533.8 68549.0 66259.0 65070.0 59254.0 71232.0 44753.9 True False 64540.3287535389 66805.95591857155 62111.94051691468 54250.224227815044 64517.08259251934 63425.25702727301 68439.00621004486 62007.157157361995 63209.102053786344 52489.55198417668 1.2295842946610596 1.2727476877438513 1.1833200735955745 1.0335432896087422 1.229141422505729 1.2083406055055104 1.3038595991574904 1.1813238028027837 1.2042225483814597 1.0 15.679742663267602 -9.37032812436148 2.0555152422608 0.9999929478079467 1.2047314609092856 0.4515321925372189 0.06781792366931597 42.61767981916795 101.08244289891105 0.06977887562008527 0.019108672411996035 4.2625734508104467e-10 9.37032812436148 0.20473851310133895 S(ph)SGFISELPSEEGK ddPTM_PC-9_AZD4547_30min_R2 3 SSGFISELPSEEGK 14 0 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(0.945)S(0.055)GFISELPSEEGK;S(0.671)S(0.329)GFISELPSEEGK;S(0.932)S(0.068)GFISELPSEEGK 311.95 6.374499999999998e-117 56677000.0 140075.0 168894.0 207660.0 221482.0 213580.0 216322.0 204918.0 223589.0 201542.0 196312.0 True False 184615.9362590022 223485.68259781835 204906.29271736628 170422.74676278906 183928.1036591564 202795.35114317387 223155.3050212332 189038.45761408456 212195.098663852 189439.1766327222 0.9745393721644434 1.1797226242758871 1.081646871357719 0.8996172269751704 0.9709084832845822 1.0705037614069983 1.1779786472250067 0.9978847088244343 1.1201225767320988 1.0 17.5313751900852 -6.973974224115486 24.035698875776305 1.0810232310297339 1.0260851022085242 0.08151121420513963 0.08531883309734097 407.61030734902783 376439.6494672373 0.03166778243004781 0.02792735614060725 1.061758571939491e-07 6.973974224115486 -0.05493812882120963 S(ph)SGFISELPSEEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSGFISELPSEEGK 14 0 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(0.995)S(0.005)GFISELPSEEGK;S(0.884)S(0.116)GFISELPSEEGK 275.66 1.269e-69 18601200.0 39348.0 47816.0 45635.0 51817.0 54952.0 45539.0 55855.0 46721.0 49476.0 44274.0 True False 46008.839241575224 52562.85647506492 46723.11147170127 48913.8614829806 44184.550076232685 43150.85467317221 50564.01004481887 45494.62325499144 50199.49290060397 52300.52572720881 0.879701276456569 1.0050158338603397 0.8933583519867765 0.9352460764564298 0.8448203810931507 0.8250558493090523 0.9667973570390604 0.8698693296561516 0.9598276920281166 1.0 15.674537828129218 -8.492568418503192 4.934081724937401 0.9998487065016503 0.9045401008934563 0.27867751580161915 0.05173691632751807 0.22094406700228922 14.784090019004745 0.050440172318165 0.013128085061669782 3.216855711173698e-09 8.492568418503192 -0.09530860560819399 S(ph)SGFISELPSEEGK ddPTM_PC-9_Lapatinib_30min_R1 2 SSGFISELPSEEGK 14 0 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(0.5)S(0.5)GFISELPSEEGK;S(0.933)S(0.067)GFISELPSEEGK 280.5 3.5300999999999994e-70 36471000.0 95302.0 80387.0 90439.0 72756.0 82635.0 85172.0 85886.0 77649.0 84297.0 62061.0 True False 93942.97600375368 80200.86884046267 83003.45452463554 78106.7189469012 77774.57176666081 81529.39210562935 90332.7568365745 81256.85601161125 74802.58417323709 72788.16115891555 1.2906353795454681 1.1018394689950093 1.140342786561366 1.0730689950577792 1.0685057917160268 1.1200913830977184 1.2410363910602786 1.116347146539481 1.0276751463733715 1.0 16.151416197744755 -14.522878723014106 0.020479773413399474 1.081892220189035e-06 1.9019423651780463 0.3365835854247613 0.06923733795585353 4513.294771107876 6.970072043916793 439.7129533105283 236.61096765212716 3.0000001538096833e-15 14.522878723014106 1.901941283285826 S(ph)SGFLNLIK ddPTM_PC-9_AZD4547_30min_R2 1 SSGFLNLIK 9 0 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(0.992)S(0.008)GFLNLIK 132.32 0.0012052 2703900.0 5668.4 6532.9 8659.3 15223.0 17569.0 13514.0 11025.0 17979.0 11574.0 13341.0 True False 7470.833289955599 8644.532167177564 8544.472024113891 11713.572543005466 15129.847613014916 12668.967443666645 12006.203641744962 15200.758666319134 12185.77801121069 12873.935650684367 0.5803068690621004 0.6714754836232251 0.6637031795059248 0.9098672589980503 1.1752309490696131 0.9840788230903712 0.9325977671099143 1.1807390590391118 0.9465464440598556 1.0 13.65216554233443 -5.849668495673464 3.1511256273407002 1.0386456382402403 0.6343278128078735 0.8211224886452572 0.08298958187687774 0.09449107312473388 1.8739984162388679 0.02370099971793933 0.038544567161012726 1.4136161700456145e-06 5.849668495673464 -0.4043178254323667 S(ph)SGFLNLIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSGFLNLIK 9 0 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(0.959)S(0.041)GFLNLIK;S(0.967)S(0.033)GFLNLIK 121.68 0.0016021000000000002 14133600.0 14715.599999999999 18647.4 22314.0 28655.4 30536.4 24249.6 23056.8 19958.0 19122.5 17897.6 True False 17206.660433651632 20498.590635626708 22846.050386316252 27049.930840060282 24553.01162738156 22977.908287018956 20872.69298722371 19434.123647248955 19402.13038628424 21142.293202676356 0.8138502417265445 0.9695537962283031 1.0805852594752694 1.2794227466600496 1.1613220662493435 1.0868219481560417 0.9872482983341411 0.9192060416979191 0.9176928065602726 1.0 14.367844246937016 -7.427408515511378 3.6025574462349526 0.9402064877638379 1.0753862983823068 0.1786629910754962 0.11553676843481049 0.43610278006459446 10.479611062031628 0.05982784802158814 0.03754868290642684 3.7375884969822807e-08 7.427408515511378 0.13517981061846895 S(ph)SGFLNLIK ddPTM_PC-9_Lapatinib_30min_R1 2 SSGFLNLIK 9 0 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(0.979)S(0.021)GFLNLIK;S(0.958)S(0.042)GFLNLIK 118.77 0.0017779 6107700.0 30737.0 23229.7 25709.9 25417.9 20618.1 21688.4 18361.5 18357.9 25201.9 19932.8 True False 30298.684743524536 23175.91305687852 23596.131265083994 27287.217157628755 19405.383894744235 20760.83769012976 19312.16862649049 19210.875052808868 22363.39663422784 23378.15792121352 1.296025326102844 0.9913489820277294 1.0093238032100333 1.167209890941327 0.8300647108357345 0.8880442060531731 0.8260774305475317 0.8217446009882915 0.9565936165541564 1.0 14.512873636937051 -6.264961219250527 24.986511470616446 0.8751719920084996 1.099456916441025 0.5717652814831142 0.09628995725253615 225.95040539190381 1603055.3833762233 0.028840743783078705 0.03401961546627597 5.43298843726738e-07 6.264961219250527 0.22428492443252546 S(ph)SGGAVLSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGGAVLSPR 10 0 F5GXA4;A6NGW2;Q7RTU9 F5GXA4 STRC;STRCP1 Putative stereocilin-like protein;Stereocilin 1 S(0.823)S(0.177)GGAVLSPR 73.9 0.026749000000000002 113730000.0 239660.0 236780.0 233150.0 293610.0 341310.0 288240.0 285280.0 286080.0 244000.0 202490.0 True False 280229.7044992353 260285.95357549484 238709.18022629857 277159.983596463 274432.7556143352 273124.18698248 258256.21315165868 278570.7031268161 247568.03839735186 239199.83409004152 1.1715296775404493 1.088152734577215 0.9979487700499062 1.158696387273129 1.1472949245902528 1.1418243161475956 1.0796671918026657 1.1645940482632369 1.034984155984658 1.0 17.867856863314145 -8.450397485494285 5.295166109175439 1.0004551191759918 1.1151618799114864 0.402377147276475 0.05003566144238279 0.20110675498615194 9.649590579342096 0.049421144334647456 0.012844169570557895 3.544887969095603e-09 8.450397485494285 0.11470676073549457 S(ph)SGGREDLESSGLQR ddPTM_PC-9_Lapatinib_30min_R1 1 SSGGREDLESSGLQR 15 1 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 S(0.866)S(0.134)GGREDLESSGLQR 80.859 0.004442300000000001 39318000.0 10270.0 8929.7 11413.0 9762.2 15022.0 10794.0 11164.0 10864.0 8357.0 7255.7 True False 10123.547916712654 8909.023828289133 10474.667195454036 10480.144753744546 14138.43549438832 10332.365782042962 11742.017294128469 11368.781100981892 7415.746656888644 8509.838077387472 1.1896287361346118 1.046908736367427 1.2308891309327672 1.231532804553898 1.6614223873374607 1.2141671425568425 1.3798167705834044 1.3359573939710165 0.8714321693845066 1.0 13.05491596567173 -8.259841449850391 24.998621897705192 0.9357160565294363 1.2878568814679705 0.4522556982595446 0.15431753467915263 130.94260505149134 2048603.0926725448 0.12506973280397554 0.041571296177414584 5.4974153423392665e-09 8.259841449850391 0.35214082493853416 S(ph)SGKTPETLVPTAPK ddPTM_PC-9_AZD4547_30min_R2 1 SSGKTPETLVPTAPK 15 1 Q14676;Q14676-2 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 S(0.496)S(0.496)GKT(0.007)PETLVPTAPK 95.365 0.0044944 0.0 24668.0 19427.0 28059.0 32062.0 26962.0 30433.0 23173.0 25554.0 24131.0 26366.0 True False 32511.91087372535 25706.39783430919 27686.919326575073 24670.601252962075 23218.791697996938 28530.019699060747 25235.35210795067 21605.216472502318 25406.51539558711 25442.934365185818 1.2778365265215705 1.0103550740390965 1.08819678301178 0.969644495358187 0.9125830914286275 1.1213336987615337 0.9918412611432436 0.8491637073931715 0.9985686018335785 1.0 14.63497744757624 -1.6671999825243575 0.9946001202993988 0.9794539033057461 199.99999999265398 0.5742792799163672 0.07334595886844528 869.5072305548061 1.686130728098514 0.023650941873036364 393653.6378555849 0.02151790656925988 1.6671999825243575 199.02054608934824 S(ph)SGKTPETLVPTAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGKTPETLVPTAPK 15 1 Q14676;Q14676-2 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 S(0.333)S(0.333)GKT(0.333)PETLVPTAPK 54.805 0.034388999999999996 11120000.0 166510.0 162370.0 148550.0 177280.0 212180.0 173340.0 192230.0 186480.0 172650.0 129800.0 True False 194696.85427759218 178489.0205340531 152091.99537901251 167347.57634951494 170604.85214687468 164249.74525236964 174020.58277532016 181585.09759189206 175174.67962828948 153331.71250376545 1.2697755154388621 1.164071134532394 0.9919148028512205 1.091408773937781 1.1126521015193451 1.0712053140888 1.1349288410970213 1.1842631548736715 1.1424556392663234 1.0 17.226296584612662 -4.902458437708797 3.9602598586911273 1.098134755126368 1.2673753560221688 0.4760105751663969 0.05752417903854486 0.20997512833755547 5.713299108833951 0.015033108049311576 0.07972481716639969 1.2518190672756624e-05 4.902458437708797 0.16924060089580073 S(ph)SGKTPETLVPTAPK ddPTM_PC-9_Lapatinib_30min_R1 3 SSGKTPETLVPTAPK 15 1 Q14676;Q14676-2 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 S(0.633)S(0.183)GKT(0.183)PET(0.001)LVPTAPK;S(0.4)S(0.4)GKT(0.197)PET(0.003)LVPTAPK;S(0.877)S(0.122)GKT(0.002)PETLVPTAPK 113.47 0.00081848 16866300.0 294169.0 268577.0 286963.0 236313.0 275295.0 276293.0 280147.0 260012.0 290936.0 235149.0 True False 289974.09611601295 267955.1264578217 263370.0098492139 253692.24633705852 259102.6893507947 264476.59246044065 294651.6408902013 272093.1067404731 258167.72398810077 275794.19133365224 1.0514148057788717 0.9715763960150018 0.9549512575868295 0.9198607306059791 0.9394784135875278 0.9589636068167958 1.0683750787692827 0.9865802663381635 0.9360883299959454 1.0 18.07323254614591 S(ph)SGNSPTPVSR ddPTM_PC-9_AZD4547_30min_R2 1 SSGNSPTPVSR 11 0 H0YBT1;O95429-2;O95429 H0YBT1 BAG4 BAG family molecular chaperone regulator 4 1 S(0.83)S(0.099)GNS(0.07)PT(0.001)PVSR 93.839 0.006883 34609000.0 33928.0 36487.0 50172.0 77085.0 64175.0 48214.0 41861.0 64475.0 40055.0 49861.0 True False 44716.39825376007 48280.70920782622 49506.686498197545 59314.24420137796 55265.40899113392 45199.170958187315 45586.5479044976 54511.87023810707 42172.2255260968 48115.381566507225 0.9293576564897665 1.0034360663042956 1.0289160116036322 1.2327501574395947 1.1486016984972593 0.9393913024613763 0.9474423026550427 1.1329406203036825 0.8764811615970346 1.0 15.55421054926906 -6.774274735348328 24.99775024469579 0.9855718236003632 1.0719048450161826 0.17030378205331465 0.09799100431475381 482.8759121830946 940427.989466606 0.03672192670902323 0.032584279106258864 1.6816099355250484e-07 6.774274735348328 0.08633302141581933 S(ph)SGNSPTPVSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSGNSPTPVSR 11 0 H0YBT1;O95429-2;O95429 H0YBT1 BAG4 BAG family molecular chaperone regulator 4 1 S(0.746)S(0.138)GNS(0.113)PT(0.003)PVSR 111.31 0.0018276 29041000.0 29429.0 23434.0 29582.0 28206.0 25737.0 24547.0 26791.0 23106.0 28536.0 22341.0 True False 29009.337063382376 23379.74001278068 27149.882149822228 30280.36333245769 24223.200260888854 23497.182031851826 28178.106890630246 24179.589112600086 25321.975182598366 26202.61208248873 1.1071162284148528 0.8922675319231024 1.0361517418321269 1.1556238453300667 0.9244574618985135 0.8967496048821427 1.0753930486747825 0.922793080189107 0.9663912553024095 1.0 14.677423017671444 S(ph)SGPTSLFAVTVAPPGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGPTSLFAVTVAPPGAR 18 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;A0A1X7SBS1;A0A1W2PP22 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 1 S(0.996)S(0.004)GPTSLFAVTVAPPGAR 166.9 1.2117000000000002e-07 3818700.0 7942.4 9604.1 8283.6 6465.7 8547.2 9195.7 9925.2 7771.7 6579.6 7762.1 True False 9286.891450449504 10557.531576714302 8481.112439727942 6103.447791082225 6872.437516588582 8713.461303895338 8985.013203774712 7567.701109796811 6675.814202619728 9169.307285250208 1.0128236693941366 1.151399036838606 0.9249458193391228 0.6656389191907943 0.7495045484672128 0.9502856685708257 0.979900980985559 0.8253296431640208 0.7280609096129296 1.0 13.162597031145086 -5.469463406209125 5.930662601940796 0.8382785362363421 1.0753272436632177 0.42996948302735727 0.10893104385614169 0.20135790004253581 15.897940756226435 0.03029876356009223 0.06285208475933149 3.3926307475147552e-06 5.469463406209125 0.23704870742687567 S(ph)SGPYGGGGQYFAKPR ddPTM_PC-9_AZD4547_30min_R2 2 SSGPYGGGGQYFAKPR 16 1 F8W6I7;P09651-2;P09651;P09651-3;H0YH80 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 S(0.786)S(0.212)GPY(0.003)GGGGQYFAKPR;S(0.498)S(0.498)GPY(0.003)GGGGQYFAKPR 85.976 0.0021693000000000003 98008000.0 40566.0 59920.0 95791.0 156602.0 109553.0 93709.0 88628.0 114862.0 78156.0 119303.0 True False 53465.14417478281 79287.96820053573 94520.74875127252 120499.82837678147 94343.45697243001 87849.36141620245 96515.72030481379 97112.71716618014 82287.16660136366 115126.23828300714 0.46440450910376324 0.6887045853580954 0.8210183026993245 1.0466756334083007 0.8194783255274248 0.7630698503346234 0.8383468594496734 0.8435324441632014 0.7147559742122609 1.0 16.81285714827912 -4.899292800510958 2.1728697714019707 0.8518058859100525 0.4151988973510991 0.6279816256573154 0.09422962493910009 0.3326885637697067 2.227539158609067 0.025781033631534625 0.2606833128972145 1.2609770995877699e-05 4.899292800510958 -0.43660698855895336 S(ph)SGPYGGGGQYFAKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSGPYGGGGQYFAKPR 16 1 F8W6I7;P09651-2;P09651;P09651-3;H0YH80 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 S(0.807)S(0.121)GPY(0.072)GGGGQYFAKPR;S(0.578)S(0.422)GPYGGGGQYFAKPR;S(0.977)S(0.023)GPYGGGGQYFAKPR 137.73 6.6597e-05 42835800.0 47036.4 54422.0 98225.0 99329.0 144909.0 135168.0 135098.0 122331.0 113189.0 83001.0 True False 54998.73350875338 59824.65649753191 100567.05652038705 93763.9181589627 116515.12168796064 128079.55213033539 122300.53941518109 119119.94087040849 114844.17499244987 98048.4242644457 0.5609343946254219 0.6101541860191375 1.0256876362352174 0.9563021421545002 1.1883426231686145 1.306288735297703 1.2473483417267899 1.214909283489666 1.1713005675920347 1.0 16.581206824611066 -5.323576780048271 1.0503443882471557 1.2051243501620528 0.4385690779951702 0.8470620467656809 0.0962240525074363 0.30111770093330603 0.4772114393674563 0.03298117792365703 0.2118199601383904 4.747043593072257e-06 5.323576780048271 -0.7665552721668826 S(ph)SGPYGGGGQYFAKPR ddPTM_PC-9_Lapatinib_30min_R1 2 SSGPYGGGGQYFAKPR 16 1 F8W6I7;P09651-2;P09651;P09651-3;H0YH80 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 S(0.5)S(0.5)GPYGGGGQYFAKPR;S(0.816)S(0.184)GPYGGGGQYFAKPR 122.5 2.6946e-05 81853000.0 120509.0 91347.0 110835.0 108894.0 82356.0 90263.0 66800.0 68568.0 72101.0 71193.0 True False 118790.51956135586 91135.4916338429 101722.57413547269 116902.4280197353 77511.98199812578 86402.66190333 70258.57714508976 71753.91959979082 63980.226122810585 83498.6151912903 1.422664547061217 1.0914611149545053 1.2182546249711135 1.4000522972976124 0.9283026050258497 1.0347795793425638 0.8414340403626047 0.8593426302389197 0.7662429607513339 1.0 16.34946465051069 -6.327295103435454 7.038925985519515 0.899620510610522 1.2643187829217302 0.7284936153061907 0.11283902548467324 0.14499878294431717 13.350649950650427 0.03572822713404729 0.04062949993226267 4.706574056458772e-07 6.327295103435454 0.3646982723112082 S(ph)SGQPSPESQTR ddPTM_PC-9_AZD4547_30min_R2 1 SSGQPSPESQTR 12 0 C9J6N8 C9J6N8 TFAP2A 1 S(0.845)S(0.107)GQPS(0.048)PESQTR 108.97 0.0013683 15377000.0 7199.2 6078.5 8454.4 12759.0 10079.0 8127.0 7934.9 10313.0 7063.3 10028.0 True False 9488.395847337575 8043.256253453877 8342.289131993171 9817.60967458496 8679.704826203959 7618.817405259638 8641.090728061869 8719.362819163984 7436.651617987255 9676.922772285645 0.9805178847259168 0.831179130259205 0.8620807800476805 1.0145383925871805 0.896948857653625 0.7873181986198808 0.8929585294211129 0.9010470605527536 0.7684934346366342 1.0 13.240332633095704 -6.532350512903291 24.942025659422228 0.8626513508215802 0.9168559895459866 0.086724879304376 0.07728760611327862 491.2470650324926 1293592.1653126744 0.024922835768674524 0.02495383683841906 2.935279673199863e-07 6.532350512903291 0.054204638724406395 S(ph)SGREEDDEELLR ddPTM_PC-9_Lapatinib_30min_R1 1 SSGREEDDEELLR 13 1 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 S(0.86)S(0.14)GREEDDEELLR 119.54 0.0017346 0.0 14685.0 15946.0 13761.0 10823.0 14295.0 16172.0 12681.0 11307.0 13842.0 10832.0 True False 14475.589207100811 15909.078016719328 12629.623698996136 11618.959524469605 13454.196205051334 15480.36125877327 13337.560131390455 11832.364498232895 12282.96819727805 12704.296767267255 1.1394246743666527 1.2522596337413356 0.9941222194632988 0.9145692781993229 1.05902722925335 1.2185138258623311 1.049846392580722 0.9313671362526023 0.9668357424493765 1.0 13.63302889831299 -5.267452641110191 24.936701831354057 1.020577472697693 1.1958421568972257 0.4186056172027449 0.08431336393677225 449.800866729781 1865309.1168724885 0.02439297201536215 0.052988542546033475 5.401910182348548e-06 5.267452641110191 0.17526468419953267 S(ph)SGRNSPSAASTSSNDSK ddPTM_PC-9_AZD4547_30min_R2 1 SSGRNSPSAASTSSNDSK 18 1 D6RA28;A0A590UJ84;B1AKN3;Q9P2R6-2;Q9P2R6 D6RA28 RERE Arginine-glutamic acid dipeptide repeats protein 1 S(0.454)S(0.454)GRNS(0.09)PS(0.002)AASTSSNDSK 76.817 0.0024596 4362300.0 3095.3 3162.3 4037.8 6313.1 4560.0 5064.4 3391.9 5527.1 3633.2 3653.3 True False 4079.541013760418 4184.451632853041 3984.256133748347 4857.712331422703 3926.9227113295024 4747.722267404567 3693.772529019026 4673.013695122787 3825.2435346751913 3525.399078977979 1.157185590161068 1.1869440988411792 1.1301574784842208 1.3779184207510953 1.1138945189910034 1.3467190979073331 1.0477601106340162 1.3255275758673835 1.0850526277961523 1.0 11.783570866052527 -8.503662555571749 8.45773332548938 1.0000095587849116 1.2086265860166656 0.31650056935201243 0.10272472194725542 0.21854717648155725 84.46318501680274 0.09020023677374497 0.023309103426788193 3.1357212161816574e-09 8.503662555571749 0.20861702723175402 S(ph)SGRNSPSAASTSSNDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGRNSPSAASTSSNDSK 18 1 D6RA28;A0A590UJ84;B1AKN3;Q9P2R6-2;Q9P2R6 D6RA28 RERE Arginine-glutamic acid dipeptide repeats protein 1 S(0.362)S(0.362)GRNS(0.264)PS(0.011)AASTSSNDSK 72.359 0.0038280000000000002 5637700.0 2483.5 3523.7 2319.8 3067.0 5978.5 3313.3 5611.5 3957.5 3249.7 4688.3 True False 2903.9074986391165 3873.509648677983 2375.1128298904923 2895.1659333481593 4807.0558420213465 3139.5447152687016 5079.938096258189 3853.6198183178567 3297.220714671611 5538.251677437623 0.5243364996338816 0.699410188319599 0.4288560665392844 0.522758101648364 0.8679735270256663 0.5668837203731543 0.9172458010446572 0.6958188328669106 0.5953540768297357 1.0 12.435214900942032 -6.245473820696605 24.618879150189205 0.7554888123092619 0.5467391813344731 0.3825465583292148 0.1420074749756298 774.1829596632354 1193788.9292007894 0.04037642270114833 0.051946533652181555 5.682326436331967e-07 6.245473820696605 -0.20874963097478882 S(ph)SGRNSPSAASTSSNDSK ddPTM_PC-9_Lapatinib_30min_R1 1 SSGRNSPSAASTSSNDSK 18 1 D6RA28;A0A590UJ84;B1AKN3;Q9P2R6-2;Q9P2R6 D6RA28 RERE Arginine-glutamic acid dipeptide repeats protein 1 S(0.358)S(0.358)GRNS(0.284)PS(0.001)AASTSSNDSK 96.34100000000001 0.00039654 32250000.0 7529.0 9489.3 8774.8 8166.6 11572.0 11714.0 10900.0 10602.0 9640.4 11193.0 True False 7421.635079350497 9467.328108870857 8053.369815707531 8767.199006978977 10891.357711427358 11213.019526667711 11464.348665890386 11094.607624503857 8554.596634087506 13127.695136264994 0.5653418214175602 0.7211721486978742 0.6134641101970946 0.6678399304657652 0.8296473675215233 0.8541499029553155 0.8732948584569391 0.845129895944584 0.6516449799672452 1.0 13.68032602027593 -6.235456947290616 4.054706054513765 0.8379654155929332 0.6421863103885292 0.5617756315628332 0.08693385889619179 0.17221203978343294 6.548415147394288 0.025954175522832388 0.03268636816328575 5.814910741308242e-07 6.235456947290616 -0.195779105204404 S(ph)SGSEGSSPNWLQALK ddPTM_PC-9_AZD4547_30min_R2 2 SSGSEGSSPNWLQALK 16 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 S(0.948)S(0.015)GS(0.036)EGSSPNWLQALK;S(0.671)S(0.1)GS(0.059)EGS(0.07)S(0.1)PNWLQALK 220.97 1.3573e-22 11103000.0 27468.0 22589.0 35104.0 46516.0 39972.0 36392.0 28919.0 42350.0 26155.0 34698.0 True False 36202.25263010733 29890.45249802906 34638.498023453874 35792.454865035965 34422.57776694358 34116.402487044295 31492.734976473694 35805.78060618587 27537.499903509233 33483.23358124925 1.081205390221951 0.8926991004467333 1.034502774034691 1.0689664956696383 1.0280541657786708 1.0189100286344392 0.940552378253866 1.069364478173854 0.8224265388433196 1.0 15.03115123976641 -7.244716985949839 22.901948752883165 0.9638662260679028 1.018056211932884 0.14239411745458785 0.07459860008258448 631.5753025234796 864966.124928411 0.027609291715563804 0.021301873519174303 5.692237525945165e-08 7.244716985949839 0.05418998586498114 S(ph)SGSEGSSPNWLQALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSGSEGSSPNWLQALK 16 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 S(0.855)S(0.006)GS(0.139)EGSSPNWLQALK;S(0.997)S(0.002)GS(0.001)EGSSPNWLQALK 203.06 9.522399999999999e-51 4323600.0 19920.9 25670.0 26772.0 26923.0 33017.0 24825.0 27567.0 24419.0 27258.0 21757.6 True False 23293.114914290316 28218.347952880158 27410.3460133754 25414.5915955437 26547.55586451765 23523.13329808516 24955.654192203412 23778.027124069173 27656.596682930354 25702.08064693318 0.9062735128048746 1.0979013077000528 1.0664640886435806 0.9888145611501774 1.0328952052247706 0.9152229199347712 0.9709585202465376 0.9251401647479622 1.0760450510931843 1.0 14.649597533424243 -6.702569906023304 24.99969340491331 0.972386342207446 1.0239015618040368 0.09049568803575703 0.06280560573056487 156.64792185079585 66521.51742310857 0.0202105708721577 0.02021056281631622 1.9834903594722156e-07 6.702569906023304 0.05151521959659078 S(ph)SGSEGSSPNWLQALK ddPTM_PC-9_Lapatinib_30min_R1 2 SSGSEGSSPNWLQALK 16 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 S(0.977)S(0.014)GS(0.01)EGSSPNWLQALK;S(0.982)S(0.011)GS(0.007)EGSSPNWLQALK 195.46 8.3026e-12 8770600.0 39419.0 43275.0 40837.0 36824.0 43894.0 37682.0 38726.0 39458.0 45688.0 38825.0 True False 38856.87783144074 43174.79939630807 37479.53949537862 39532.159801262926 41312.24121892431 36070.42870103231 40731.04279222675 41291.362728511005 40542.13632403117 45535.8495189394 0.8533249789329015 0.9481496414896287 0.8230776386370046 0.8681546565815269 0.9072465245595475 0.792132552309797 0.8944829891728664 0.9067880178964703 0.8903344672897509 1.0 15.47471517890002 -9.04632748879484 0.8460160497854647 1.000550033696152 0.8704107704823083 0.45623394269035356 0.041670354356792054 1.64820501834706 1.8126284931863152 0.04243368185651988 0.013626243095956059 8.988195523268768e-10 9.04632748879484 -0.13013926321384361 S(ph)SGSETEQVVDFSDR ddPTM_PC-9_AZD4547_30min_R2 1 SSGSETEQVVDFSDR 15 0 O95251-2;O95251-4;O95251 O95251-2 KAT7 Histone acetyltransferase KAT7 1 S(0.871)S(0.127)GS(0.002)ETEQVVDFSDR 268.93 7.417999999999998e-62 7319500.0 4437.1 4980.2 5130.0 8069.3 6449.6 5912.7 5203.0 7870.4 5492.4 5552.3 True False 5848.005502586621 6589.9522568809725 5061.972848117547 6209.047554442232 5554.184368199727 5542.977934302776 5666.0569204534295 6654.21052379989 5782.717051043169 5357.915666988591 1.0914702406791492 1.2299469917907175 0.9447653085145743 1.1588550362406167 1.0366315398393438 1.0345399739033592 1.0575114041759506 1.2419401381768818 1.0792848209000157 1.0 12.387456158157637 -11.384497585688887 14.13776197990353 0.9989174739810763 1.0979125516265615 0.1016456174433199 0.08668177318868532 0.0029238108415044297 2.8618388223891466e-05 0.08296850799244851 0.019927421452785345 4.125745306768435e-12 11.384497585688887 0.09899507764548521 S(ph)SGSETEQVVDFSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSGSETEQVVDFSDR 15 0 O95251-2;O95251-4;O95251 O95251-2 KAT7 Histone acetyltransferase KAT7 1 S(0.433)S(0.433)GS(0.092)ET(0.041)EQVVDFSDR;S(0.622)S(0.007)GS(0.37)ETEQVVDFSDR;S(0.6)S(0.126)GS(0.274)ET(0.001)EQVVDFSDR;S(0.884)S(0.01)GS(0.105)ETEQVVDFSDR 216.77 8.7703e-18 36296400.0 41004.3 58726.0 59318.0 62032.0 70136.0 60467.0 66038.0 61698.9 57129.2 51085.4 True False 47945.51811815905 64555.929173386794 60732.3660847677 58556.548150457485 56393.35427548873 57296.0040739301 59782.40256628327 60079.369250388234 57964.60647217203 60346.77862819609 0.7945000413950392 1.069749382500163 1.0063895284112392 0.9703342826504721 0.9344882288238634 0.949445941877657 0.9906477847742295 0.9955687878642968 0.960525280550584 1.0 15.880989140071302 -4.744373178009313 24.9779735610843 0.9836975634483899 0.7944994730682217 0.722714642202809 0.03561617525685493 601.424042826419 880192.7204030724 0.009434050741583898 0.27110016042912244 1.8014691198149254e-05 4.744373178009313 -0.18919809038016822 S(ph)SGSETEQVVDFSDR ddPTM_PC-9_Lapatinib_30min_R1 3 SSGSETEQVVDFSDR 15 0 O95251-2;O95251-4;O95251 O95251-2 KAT7 Histone acetyltransferase KAT7 1 S(0.583)S(0.413)GS(0.003)ETEQVVDFSDR;S(0.759)S(0.146)GS(0.094)ET(0.001)EQVVDFSDR;S(0.317)S(0.317)GS(0.317)ET(0.05)EQVVDFSDR 281.49 8.172699999999999e-76 19197300.0 38110.9 32493.1 37194.1 34097.6 35600.9 37052.6 33240.5 34773.0 40961.0 30803.100000000002 True False 37567.431577316915 32417.864223320128 34136.14467137796 36605.251250259156 33506.92505606239 35467.94667182923 34961.53044298437 36388.68052507762 36347.54084154791 36127.37479244925 1.0398605432346177 0.8973213362321465 0.9448830663032991 1.013227544502065 0.9274663672231579 0.9817471342878243 0.9677296134534373 1.0072329012038534 1.006094161293576 1.0 15.1408048042197 -7.736660697455381 5.7772334444462965 1.0052010172065977 0.9644689345355476 0.16087881625827638 0.03828919669249786 0.2849313413185572 28.3202660202754 0.018628718620785908 0.010060792382783477 1.833746519479117e-08 7.736660697455381 -0.04073208267105011 S(ph)SGSPYGGGYGSGGGSGGYGSR ddPTM_PC-9_AZD4547_30min_R2 2 SSGSPYGGGYGSGGGSGGYGSR 22 0 P51991;P51991-2;H7C1J8 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 1 S(0.579)S(0.06)GS(0.361)PYGGGYGSGGGSGGYGSR;S(0.333)S(0.333)GS(0.333)PYGGGYGSGGGSGGYGSR 269.98 2.0556999999999995e-87 172150500.0 31582.2 33813.6 41948.6 56094.5 48480.1 47886.4 35805.6 40584.1 32618.2 46213.9 True False 41624.68264943119 44743.1849390126 41392.334155271696 43162.77967638578 41749.47494243975 44892.05583797532 38992.22903536175 34312.7598748408 34342.331460624926 44595.96542741637 0.9333732827732771 1.003301184539571 0.9281632039705733 0.9678628831712766 0.9361715693853625 1.0066393990514872 0.8743443193045083 0.7694139939786181 0.7700770940034904 1.0 15.44462557576798 -7.4636082739614045 5.201821996562637 0.8258893410241006 0.9612225263528347 0.3921255483115085 0.0656351472784787 0.1751013456281381 9.843413962081584 0.027093767970077662 0.01755236330926703 3.438679709660075e-08 7.4636082739614045 0.13533318532873406 S(ph)SGSPYGGGYGSGGGSGGYGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SSGSPYGGGYGSGGGSGGYGSR 22 0 P51991;P51991-2;H7C1J8 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 1 S(0.761)S(0.014)GS(0.224)PYGGGYGSGGGSGGYGSR;S(0.609)S(0.013)GS(0.378)PYGGGYGSGGGSGGYGSR;S(0.907)S(0.088)GS(0.005)PYGGGYGSGGGSGGYGSR;S(0.981)S(0.012)GS(0.007)PYGGGYGSGGGSGGYGSR;S(0.851)S(0.077)GS(0.072)PYGGGYGSGGGSGGYGSR 314.43 1.5026999999999994e-167 362928000.0 69853.8 67386.5 82712.9 84280.8 89388.6 79809.7 87441.1 70538.8 65976.8 60908.2 True False 81678.66866456106 74076.18637813632 84685.08922642014 79558.82001804037 71873.54551143412 75624.33883505277 79158.04598925813 68687.23124203665 66941.58588415713 71950.37451095416 1.1352083879997845 1.0295455288680744 1.176993028903931 1.1057457387650964 0.998932194584917 1.0510624767288634 1.1001755936267799 0.9546473066874626 0.9303855100012792 1.0 16.134714575947825 -7.353860031474306 0.7648439733390865 0.9567881733479104 1.1035094173288698 0.47711890206071594 0.055027368038940885 0.6128198870071089 0.6916490991552757 0.048336986991656894 0.028107066763509554 4.4273103691004216e-08 7.353860031474306 0.14672124398095931 S(ph)SGSPYGGGYGSGGGSGGYGSR ddPTM_PC-9_Lapatinib_30min_R1 2 SSGSPYGGGYGSGGGSGGYGSR 22 0 P51991;P51991-2;H7C1J8 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 1 S(0.955)S(0.006)GS(0.039)PYGGGYGSGGGSGGYGSR;S(0.478)S(0.045)GS(0.478)PYGGGYGSGGGSGGYGSR 394.57 0.0 475170000.0 96490.0 85420.0 106053.0 91915.0 91247.0 87662.0 81028.0 81418.0 91861.0 63008.0 True False 95114.0349059013 85222.21523818935 97333.73171641851 98674.73571945146 85880.0308585044 83912.90061010275 85223.23336695103 85200.97751102217 81514.64684078585 73898.84884711733 1.2870841209268922 1.1532279131234902 1.3171210815175687 1.3352675617936989 1.1621294810176794 1.1355102538024995 1.1532416904526035 1.152940523976047 1.103057058566963 1.0 16.173264270639546 -6.4454428739112455 5.0347462685059154 1.1236103890761966 1.2673290874425882 0.6068162275080473 0.061807894033399216 0.17222422458529132 7.80841017715151 0.019722358597454727 0.022154226586391892 3.5855610881363515e-07 6.4454428739112455 0.14371869836639162 S(ph)SGSVASLPQSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGSVASLPQSDR 13 0 E3W994;J3KR49;O75122;A0A0U1RQI6;B3KR06;E7ENG2;O75122-2;E7ERI8;E7EW49;O75122-3 E3W994;E7ERI8 CLASP2 CLIP-associating protein 2 1 S(0.633)S(0.015)GS(0.352)VASLPQSDR 89.992 0.0058314 4308800.0 18168.0 13570.0 15804.0 17680.0 24148.0 22914.0 19400.0 19138.0 22183.0 19434.0 True False 21243.48356564346 14917.139918994295 16180.82729700376 16689.446919333368 19416.372747868434 21712.349502208403 17562.291556163025 18635.64777838715 22507.384408887094 22957.230360540634 0.9253504552603697 0.6497795981798478 0.7048248871003056 0.726979982220309 0.8457628574064274 0.945773909187584 0.7650004499823924 0.8117550543212951 0.9804050425687785 1.0 14.48666098035514 -7.991992957418535 0.4169589737936618 1.0110678513280167 0.7420197383533821 0.39649210774335764 0.09102011209036431 1.1085362127655016 0.5378073345552157 0.11451658727799881 0.08347854339909139 1.0186079058117494e-08 7.991992957418535 -0.2690481129746346 S(ph)SGTGTEPVAK ddPTM_PC-9_Lapatinib_30min_R1 2 SSGTGTEPVAK 11 0 B8ZZI9;Q6ULP2-7;Q6ULP2-8;Q6ULP2-6;Q6ULP2;Q6ULP2-9;A0A0U1RR74 B8ZZI9 AFTPH Aftiphilin 1 S(0.946)S(0.053)GTGTEPVAK;S(0.991)S(0.009)GTGTEPVAK 142.89 0.00013036 3767900.0 30498.0 56466.0 45856.0 40169.0 56982.0 57040.0 66816.0 64417.0 48192.0 56416.0 True False 30063.092927351758 56335.25644626073 42085.89668927891 43123.1622598558 53630.43079092233 54600.53216673434 70275.40554680116 67410.04898582012 42764.10947574222 66167.43043040516 0.45434880471854033 0.8514046273190872 0.6360515500680477 0.6517279268568953 0.810526122022084 0.825187434536439 1.062084549599017 1.0187799125239108 0.6463014990543039 1.0 16.013833634058173 -6.589794153500431 1.8451186580529926 0.9293931433588959 0.660761484343969 0.4372461232680599 0.14068669362929326 0.33988942630110996 2.360086190834916 0.05363245380359198 0.055585060649743084 2.5716143853739485e-07 6.589794153500431 -0.2686316590149269 S(ph)SGVVPQSAPPVPTASSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSGVVPQSAPPVPTASSR 18 0 P41162 P41162 ETV3 ETS translocation variant 3 1 S(0.84)S(0.002)GVVPQS(0.158)APPVPTASSR 179.83 9.9034e-09 13781000.0 21178.0 24909.0 27380.0 38579.0 89220.0 142840.0 118010.0 110730.0 158630.0 100780.0 True False 20875.99783643044 24851.324740904405 25128.92208985642 41416.22835577134 83972.25501326895 136731.06617630317 124119.98037263544 115874.9200397387 140763.41895204582 118199.68871909089 0.1766163520620057 0.2102486479466555 0.21259719346280945 0.35039202560168875 0.7104270402338738 1.1567802560060312 1.0500872017321001 0.9803318544697935 1.1908950055408274 1.0 16.850866710595106 -6.389532567226877 1.998997701971654 1.0761934498056618 0.20481493439485224 0.9688142763765196 0.07095307071476178 0.050424730908691 0.3977542401523366 0.024634672351485153 0.029254355458431712 4.0781897876421997e-07 6.389532567226877 -0.8713785154108096 down S(ph)SHYGGSLPNVNQIGSGLAEFQSPLHSPLDSSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSHYGGSLPNVNQIGSGLAEFQSPLHSPLDSSR 33 0 Q53ET0 Q53ET0 CRTC2 CREB-regulated transcription coactivator 2 1 S(0.218)S(0.218)HY(0.183)GGS(0.199)LPNVNQIGS(0.183)GLAEFQSPLHSPLDSSR 51.089 0.0050093 4524300.0 10137.0 5551.3 25857.0 10567.0 13196.0 22459.0 7977.0 17025.0 32147.0 6807.7 True False 9992.444521101874 5538.446305920858 23731.137270906416 11344.132430478645 12419.837224334202 21498.480924486095 8390.010028239236 17816.043652818167 28526.266337082605 7984.401874309943 1.2514956885189947 0.6936582593294782 2.972187227607127 1.4207867551079483 1.5555125380518993 2.6925599766787935 1.0508000674708458 2.231356078173098 3.5727493162470614 1.0 12.962968621504952 -5.237378199932887 24.740254425882867 2.051388342178065 0.9725767798772673 0.2256958713822802 0.8069471509957977 1017.3693558888314 1046078.0199206562 0.19926913481811365 0.526616773755732 5.789243278168741e-06 5.237378199932887 -1.0788115623007979 S(ph)SIDSQASLSGPLSGGAPGAGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSIDSQASLSGPLSGGAPGAGAR 23 0 A6NKD9 A6NKD9 CCDC85C Coiled-coil domain-containing protein 85C 1 S(0.489)S(0.489)IDS(0.02)QAS(0.001)LSGPLSGGAPGAGAR 110.38 9.8999e-07 3638500.0 7282.9 10987.0 12247.0 10041.0 14842.0 6917.3 9764.6 7181.9 6471.9 8192.7 True False 8515.751126168241 12077.716749446592 12539.014927006136 9478.435323361227 11933.81664418848 6554.544610789306 8839.62639841802 6993.382734852056 6566.539293868112 9677.971656622487 0.8799107321564683 1.247959508249024 1.2956242663126505 0.9793824222325842 1.2330906792873642 0.6772642908397166 0.9133759337235918 0.7226083091560401 0.6785036706916505 1.0 13.240488998736268 -6.760146999613818 24.99999933662112 0.7882025375174248 1.1350482982711356 0.5432089876594629 0.15054679475866378 25.469995011773733 492699.2785357301 0.04959917693294288 0.04702442667899798 1.737212718992126e-07 6.760146999613818 0.3468457607537109 S(ph)SIDSQASLSGPLSGGAPGAGAR ddPTM_PC-9_Lapatinib_30min_R1 1 SSIDSQASLSGPLSGGAPGAGAR 23 0 A6NKD9 A6NKD9 CCDC85C Coiled-coil domain-containing protein 85C 1 S(0.5)S(0.5)IDSQASLSGPLSGGAPGAGAR 133.98 1.4402000000000002e-06 4159100.0 9147.5 11634.0 15178.0 9319.9 12577.0 11815.0 10073.0 9883.3 11662.0 10333.0 True False 9017.054972553948 11607.06218779083 13930.123428774308 10005.316536274997 11837.245587333378 11309.699992110207 10594.53065243247 10342.514198760524 10348.502753695757 12119.045282142959 0.7440400429760173 0.957753842614441 1.1494406617408979 0.8255861995183337 0.9767473684395912 0.9332170751746182 0.8742050554133324 0.853409980569996 0.853904124687442 1.0 13.564988429765455 -7.216313723775049 6.307072074675874 0.8831754981669389 0.9398005208337028 0.017756601734555177 0.10606836849312042 0.7172400878768826 75.16344619141216 0.0414004667289803 0.03158085518523502 6.076958579712474e-08 7.216313723775049 0.05662502266676395 S(ph)SIEDAQCPGLPDLIEENHVVNK ddPTM_PC-9_AZD4547_30min_R2 4 SSIEDAQCPGLPDLIEENHVVNK 23 0 Q15398-1;Q15398;Q15398-3 Q15398-1 DLGAP5 Disks large-associated protein 5 1 S(0.5)S(0.5)IEDAQCPGLPDLIEENHVVNK;S(0.5)S(0.5)IEDAQCPGLPDLIEENHVVNK;S(0.5)S(0.5)IEDAQCPGLPDLIEENHVVNK;S(0.5)S(0.5)IEDAQCPGLPDLIEENHVVNK 166.78 5.127299999999999e-10 31128500.0 81542.0 83316.0 123253.0 149762.0 133003.0 146701.0 99501.0 171212.0 124001.0 132819.0 True False 107470.65982103601 110246.2676668196 121618.58468792056 115236.68469983482 114537.82924889446 137527.76327906927 108356.39624102184 144755.1194603612 130555.43970694125 128169.04723695728 0.8385071289665252 0.8601629647991198 0.9488920087162206 0.8990991755348444 0.8936465684818456 1.073018534848041 0.8454178179283328 1.1294077827756634 1.018619101268437 1.0 16.967688368301125 -6.327728682757886 0.49741368695229426 1.0390362573037584 0.8338979276889861 0.40092953663695274 0.07413064660596702 1.2708094390795666 0.6207400787754364 0.06099157421799543 0.12671406869256133 4.701877577553597e-07 6.327728682757886 -0.2051383296147723 S(ph)SIEDAQCPGLPDLIEENHVVNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSIEDAQCPGLPDLIEENHVVNK 23 0 Q15398-1;Q15398;Q15398-3 Q15398-1 DLGAP5 Disks large-associated protein 5 1 S(0.5)S(0.5)IEDAQCPGLPDLIEENHVVNK;S(0.5)S(0.5)IEDAQCPGLPDLIEENHVVNK;S(0.5)S(0.5)IEDAQCPGLPDLIEENHVVNK;S(0.5)S(0.5)IEDAQCPGLPDLIEENHVVNK 210.23 8.3468e-31 26946000.0 80277.0 93790.0 95057.0 102339.0 115380.0 86886.8 98057.0 84604.0 83888.0 67678.5 True False 93866.31055697697 103100.85136348355 97323.51938568015 96605.27761751454 92772.11726226033 82330.30325253028 88768.33108879799 82383.23464534778 85114.70329949602 79948.07630728862 1.1740909211647843 1.2895976504450823 1.217334098341619 1.208350245304243 1.1604046219408857 1.0297971765585119 1.1103247906504694 1.0304592486841007 1.0646247818690338 1.0 16.28677569986764 -6.531242086646441 2.0657546344571265 1.0508676418419396 1.22991176461609 0.8176364176886554 0.03904404768930331 0.1272606984054569 1.0940904699389993 0.01372451470746854 0.014746705772877382 2.9427807966297605e-07 6.531242086646441 0.17904412277415038 S(ph)SIEDAQCPGLPDLIEENHVVNK ddPTM_PC-9_Lapatinib_30min_R1 4 SSIEDAQCPGLPDLIEENHVVNK 23 0 Q15398-1;Q15398;Q15398-3 Q15398-1 DLGAP5 Disks large-associated protein 5 1 S(0.5)S(0.5)IEDAQCPGLPDLIEENHVVNK;S(0.5)S(0.5)IEDAQCPGLPDLIEENHVVNK;S(0.5)S(0.5)IEDAQCPGLPDLIEENHVVNK;S(0.5)S(0.5)IEDAQCPGLPDLIEENHVVNK 168.45 3.7982999999999997e-10 23195200.0 60508.3 89507.0 118268.0 91661.0 96263.0 103055.0 100709.0 100018.0 117571.0 118715.0 True False 59645.44054613679 89299.75204079371 108544.46156768208 98402.05571213244 90600.99960033978 98647.57788293838 105923.21924707852 104665.20141366024 104328.91590248352 139234.72957220604 0.4283804818625021 0.641361191386403 0.7795789304951519 0.7067349935929735 0.6507069024998883 0.7084983623412757 0.7607528636894259 0.7517176334901536 0.7493023918890823 1.0 17.087159584562286 -14.52287664482241 0.04641292072483902 2.320485234569324 2.8831444476448487e-09 0.7018653142706763 0.07361277167656204 398.96223909004414 1.3694828014296385 67.59988679574538 16.739648886502362 3.00001450948442e-15 14.52287664482241 -2.3204852316861797 S(ph)SINSVDGESPNGSSDR ddPTM_PC-9_AZD4547_30min_R2 1 SSINSVDGESPNGSSDR 17 0 Q9NUY8-2;Q9NUY8;E9PGE5 Q9NUY8-2 TBC1D23 TBC1 domain family member 23 1 S(0.979)S(0.021)INS(0.001)VDGESPNGSSDR 197.1 3.1221e-12 25529000.0 11608.0 11902.0 13268.0 15842.0 16614.0 14166.0 9822.3 14267.0 13422.0 12638.0 True False 15299.102538600766 15749.088743704537 13092.057650842798 12189.871656460136 14307.432878514977 13280.197780596543 10696.465671683585 12062.362973044945 14131.459518443911 12195.547466707818 1.254482636418351 1.291380217796487 1.0735112701239802 0.9995345997985596 1.1731685615239758 1.0889382224823996 0.877079581780439 0.9890792525693128 1.158739249469601 1.0 13.574066902732845 -5.312492753697403 4.733630488913244 1.0412924343965548 1.2742140572023353 0.5524857523860098 0.08229200789924251 0.14727250665472474 7.312593598631255 0.022980488333053942 0.051999236098917434 4.869756503979998e-06 5.312492753697403 0.23292162280578044 S(ph)SISGSLPSSGSLQAVSSR ddPTM_PC-9_AZD4547_30min_R2 1 SSISGSLPSSGSLQAVSSR 19 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 S(0.988)S(0.012)ISGSLPSSGSLQAVSSR 225.86 3.5203000000000004e-35 6938900.0 17142.0 16326.0 20065.0 26748.0 43003.0 24073.0 17585.0 53510.0 30839.0 32195.0 True False 22592.799424250043 21603.060227669328 19798.92498976191 20581.66185248049 37032.77573581197 22567.711504468476 19150.03093334107 45241.25903747357 32469.08658093371 31067.862849395333 0.727208032743384 0.6953507015397998 0.6372799148026125 0.6624743373000009 1.1919962411103773 0.7264005127699895 0.6163935712659998 1.4562076334888316 1.045102031585853 1.0 14.923135381787292 -7.750841627214381 24.999911746371456 1.1879911655699555 0.7571081225786778 0.4975336395781831 0.19120460259550376 164.84449604327148 388867.5612029705 0.09247001917831707 0.052672789658561696 1.7748365868997767e-08 7.750841627214381 -0.4308830429912778 S(ph)SISGSLPSSGSLQAVSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSISGSLPSSGSLQAVSSR 19 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 S(0.607)S(0.384)IS(0.009)GSLPSSGSLQAVSSR;S(0.796)S(0.112)IS(0.076)GS(0.016)LPSSGSLQAVSSR 188.16 4.752e-11 8552900.0 25834.0 30848.0 25722.0 22962.0 30542.0 16895.4 14089.9 22737.0 10817.7 14459.0 True False 30207.185955241803 33910.38557267029 26335.310031228215 21675.51358380843 24557.51434758148 16009.37548134816 12755.202669957802 22140.177841842862 10975.888397422254 17080.302242618975 1.7685393107311924 1.9853504399972906 1.5418526942407398 1.2690357158741272 1.437768137750237 0.9373004794611522 0.7467785106361214 1.2962404018002929 0.6426050453624342 1.0 14.060045883785929 -5.904988495377684 0.7581581123969651 0.9119290120784347 1.9797235600582828 0.7571377692547309 0.2039917725930589 0.4156294215417565 0.45186600814989836 0.10231587385894386 0.2934292470548712 1.2445475798628841e-06 5.904988495377684 1.067794547979848 S(ph)SITEPEGPGGPNIQK ddPTM_PC-9_AZD4547_30min_R2 1 SSITEPEGPGGPNIQK 16 0 H0YJL1;A0A3B3ISJ2;Q96KQ4 H0YJL1 PPP1R13B Apoptosis-stimulating of p53 protein 1 1 S(0.998)S(0.002)ITEPEGPGGPNIQK 222.75 6.172399999999999e-24 6954400.0 49205.0 65111.0 62385.0 73342.0 69823.0 78340.0 68634.0 79412.0 68103.0 75580.0 True False 64851.16647241998 86156.857434998 61557.73413836514 56434.13502260449 60129.28168271048 73441.38741577962 74742.29303832413 67140.7001062202 71702.78554496987 72933.96720476141 0.8891764558803027 1.1812994786518805 0.8440200978721257 0.773770263506525 0.8244345397241055 1.006957255041312 1.0247940144060155 0.9205683261096073 0.9831192281596993 1.0 16.154303250409086 -6.798661189528742 24.991840069882446 0.9844799573340939 0.9076216025645701 0.13803141607894387 0.10515661123253048 435.88131012807327 292660.846604055 0.040608574504880174 0.03581427246123361 1.5897865208987273e-07 6.798661189528742 -0.07685835476952374 S(ph)SITEPEGPGGPNIQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSITEPEGPGGPNIQK 16 0 H0YJL1;A0A3B3ISJ2;Q96KQ4 H0YJL1 PPP1R13B Apoptosis-stimulating of p53 protein 1 1 S(0.843)S(0.156)IT(0.001)EPEGPGGPNIQK 164.7 5.8274e-05 6016300.0 28864.0 40405.0 29421.0 28633.0 34810.0 23836.0 31689.0 22279.0 29900.0 24701.0 True False 33750.10511001388 44416.14137265765 30122.50821976385 27028.78583943848 27989.230385675848 22585.998199120157 28687.188511507757 21694.19985655175 30337.230934757423 29179.095766991584 1.156653563891215 1.5221904656450234 1.0323317919206902 0.9263064919926131 0.9592219926615494 0.7740472281759406 0.9831417923498407 0.7434843091023057 1.0396905777003536 1.0 14.832647555721978 -5.4496490081823 4.7295036588293815 0.909588931043248 1.3365677773848619 0.6511531320317083 0.12135996255822623 0.1129155954839097 4.67628385405264 0.029980107960744944 0.06368110104717217 3.551002612517728e-06 5.4496490081823 0.42697884634161387 S(ph)SITEPEGPNGPNIQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSITEPEGPNGPNIQK 16 0 Q13625-2;Q13625;Q13625-3 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 S(0.487)S(0.487)IT(0.025)EPEGPNGPNIQK;S(0.496)S(0.496)IT(0.009)EPEGPNGPNIQK 184.51 7.4555e-08 43704900.0 77628.0 108238.0 90553.0 74679.0 91984.0 57191.0 77394.0 76403.0 64385.0 60364.0 True False 90768.88717711189 118983.1533199781 92712.12694416466 70494.97774258463 73960.39551266909 54191.803280998545 70062.68003596287 74397.50220567001 65326.50882054703 71307.51535883897 1.2729217491359497 1.668592051219598 1.3001732913790618 0.9886051615714637 1.037203373872727 0.7599732371586716 0.982542719142411 1.0433332564075664 0.9161237562661682 1.0 16.121766515118317 -5.6636960680445245 3.1402702565834857 0.9548323170040061 1.4759355253608055 0.764244281144502 0.11753475167352667 0.10514581338187748 2.0556203787600236 0.03213580939014268 0.06007574112085634 2.1692216583796515e-06 5.6636960680445245 0.5211032083567995 S(ph)SITEPEGPNGPNIQK ddPTM_PC-9_Lapatinib_30min_R1 1 SSITEPEGPNGPNIQK 16 0 Q13625-2;Q13625;Q13625-3 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 S(0.683)S(0.317)ITEPEGPNGPNIQK 316.86 3.433199999999999e-147 49583000.0 48072.0 70396.0 63054.0 66127.0 86081.0 67489.0 85968.0 83680.0 70876.0 60889.0 True False 47386.48446467486 70233.00238711745 57869.943515478684 70990.20017320536 81017.8848217576 64602.652794543035 90419.00239534535 87568.078288859 62893.19852263256 71413.58252050742 0.6635500249699301 0.9834684090655871 0.8103492567238244 0.994071403053047 1.1344884539085007 0.9046269703104654 1.2661317245830688 1.226210409815424 0.8806895873704682 1.0 16.123910873571077 -4.036320050923046 0.5210270511819435 1.0935417439811896 0.05586998523688778 0.4150308037757813 0.1348860067111059 8.553283977451336 0.9928526356587605 0.0757148918125456 6.389419509035877 9.197715013988863e-05 4.036320050923046 -1.0376717587443018 S(ph)SKASLGSLEGEAEAEASSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSKASLGSLEGEAEAEASSPK 21 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(0.331)S(0.331)KAS(0.331)LGS(0.008)LEGEAEAEASSPK 84.10700000000001 0.00022138 6198400.0 59256.0 33654.0 54305.0 91738.0 101270.0 110720.0 83397.0 108080.0 84981.0 73646.0 True False 69286.87044065223 36994.946708462354 55599.83715285937 86598.21727860908 81426.87047277762 104913.64828857961 75497.03241800654 105243.01452022599 86223.6863567433 86997.43681858483 0.7964242737994187 0.42524180092348773 0.6390974169595518 0.9954111344589585 0.9359686152889369 1.2059395325330715 0.8678075490366457 1.2097254628281582 0.9911060544984214 1.0 16.40868527541207 -5.763828048236248 3.9534215113331044 1.0394100036796252 0.591182542228512 0.674003387775868 0.13057555352872807 0.11009513893377493 3.81894908514581 0.034911386731965914 0.05846709214507026 1.722550455535198e-06 5.763828048236248 -0.44822746145111325 S(ph)SKASLGSLEGEAEAEASSPK ddPTM_PC-9_Lapatinib_30min_R1 2 SSKASLGSLEGEAEAEASSPK 21 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(0.324)S(0.324)KAS(0.324)LGS(0.028)LEGEAEAEASSPK;S(0.327)S(0.327)KAS(0.327)LGS(0.02)LEGEAEAEASSPK 73.758 0.0017636 10832000.0 154200.0 83538.0 95726.0 90654.0 89812.0 75940.0 57428.0 56864.0 94166.0 71782.0 True False 152001.0797231832 83344.5728935596 87855.77779304572 97320.99757287883 84529.43473718574 72692.22322478617 60401.340842637925 59506.10903223803 83560.0334680599 84189.42305649731 1.8054652734842864 0.9899648895043412 1.043548875897249 1.1559765352895846 1.0040386507989283 0.8634365290281694 0.7174457152664435 0.7068121727393837 0.9925241251740727 1.0 16.36135137456995 -2.3231849406879874 1.0713880738824404 0.9015188909615084 199.99999999549755 0.7735267659327363 0.13889380426172962 185.5606373303891 1.2539858832715207 0.047487543148490886 89551.06749271142 0.004751328514885829 2.3231849406879874 199.09848110453603 S(ph)SLETLEDIEENAPLRR ddPTM_PC-9_AZD4547_30min_R2 1 SSLETLEDIEENAPLRR 17 1 Q8TDN4-2;Q8TDN4;V9GYB4 Q8TDN4-2 CABLES1 CDK5 and ABL1 enzyme substrate 1 1 S(0.497)S(0.497)LET(0.006)LEDIEENAPLRR 112.44 0.00011918 2818100.0 0.0 0.0 659.36 0.0 1126.5 838.26 715.71 562.28 0.0 545.47 True False 0.0 0.0 650.6164555818295 0.0 970.1049198054129 785.8434696853633 779.4068034860122 475.39254590900066 0.0 526.3732613281466 0.0 0.0 1.2360362947391974 0.0 1.842998098645135 1.4929395685915365 1.480711238103947 0.9031472166908494 0.0 1.0 9.039942394788133 -5.370261412440879 1.3970955568190757 1.0775257358453383 4.3321315811953863e-19 0.28392693674894576 0.5882201314972235 0.77084303261724 2.5397248976516953 0.18952895721681695 0.8564574119255655 4.263228274473122e-06 5.370261412440879 -1.0775257358453383 S(ph)SLETLEDIEENAPLRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSLETLEDIEENAPLRR 17 1 Q8TDN4-2;Q8TDN4;V9GYB4 Q8TDN4-2 CABLES1 CDK5 and ABL1 enzyme substrate 1 1 S(0.713)S(0.205)LET(0.082)LEDIEENAPLRR 135.79 2.0039000000000002e-05 3017800.0 855.2 0.0 2086.7 1219.6 2770.7 1909.2 2035.4 971.05 1224.1 912.04 True False 999.9684690300678 0.0 2136.4548418538193 1151.269765996549 2227.8012246363705 1809.0781910454855 1842.5921769801153 945.5609664125216 1242.0001467303196 1077.385632295333 0.928143497606952 0.0 1.9829991952855135 1.0685772405780172 2.0677844198554207 1.6791371045029688 1.7102438734536827 0.8776439355312698 1.1527907088238045 1.0 10.073319015714231 -5.259566653531114 24.996998148977863 1.465032714272359 0.4640717485907875 0.4349354187804997 0.445448859148351 141.965026124053 1894900.9357984175 0.11382528265248168 0.271316118655367 5.500894888125253e-06 5.259566653531114 -1.0009609656815714 S(ph)SLETLEDIEENAPLRR ddPTM_PC-9_Lapatinib_30min_R1 1 SSLETLEDIEENAPLRR 17 1 Q8TDN4-2;Q8TDN4;V9GYB4 Q8TDN4-2 CABLES1 CDK5 and ABL1 enzyme substrate 1 1 S(0.498)S(0.498)LET(0.004)LEDIEENAPLRR 182.28 2.9883000000000004e-07 2703800.0 1169.2 864.49 1158.5 993.66 979.31 974.93 895.21 868.89 1185.6 2331.3 True False 1152.5269935949793 862.4883265191074 1063.2526019393226 1066.7370711525894 921.7089111975387 933.2345165728317 941.5595935038291 909.2618014388945 1052.0652430785192 2734.262098738014 0.4215129903336344 0.3154373265522661 0.38886272184003934 0.3901370946278109 0.33709603465701005 0.34131128724037163 0.34435601251921005 0.33254376084083526 0.38477117594692 1.0 11.416935826957122 -8.706033486950714 7.409462165388117 0.9999999935042099 0.357738120064682 0.9750770231360019 0.03063492892846926 3.731341083773981 151.05825492820597 0.02867667873786189 0.007415954675338859 1.9677345586271236e-09 8.706033486950714 -0.6422618734395279 S(ph)SLGQSASETEEDTVSVSKK ddPTM_PC-9_AZD4547_30min_R2 1 SSLGQSASETEEDTVSVSKK 20 1 E9PPJ0;Q13435;E9PJ04;H0YCG1 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 S(0.299)S(0.299)LGQS(0.141)AS(0.141)ET(0.115)EEDT(0.003)VSVSKK 86.99700000000001 0.00034013 6926000.0 13249.0 11533.0 18024.0 24443.0 24009.0 21204.0 18709.0 16697.0 16988.0 18017.0 True False 17461.906403680365 15260.81670989282 17784.989983327614 18808.04399058547 20675.764775506563 19878.110528008536 20374.06475586454 14116.86230888985 17885.950998310636 17386.230313947995 1.0043526450740536 0.8777530513701941 1.0229353725436223 1.0817781457488707 1.1892034329557661 1.143324928352148 1.1718506190223175 0.8119564767047106 1.028742325123908 1.0 14.085657540663215 -5.476526795431135 5.610006513368277 1.065768084865781 0.9415512823575078 0.1673069492530087 0.10532415657901747 0.36354934866446137 27.630522952488757 0.030266748740579504 0.062451487680761406 3.3378991010699957e-06 5.476526795431135 -0.12421680250827305 S(ph)SLGSHQLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSLGSHQLPR 10 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 S(0.467)S(0.467)LGS(0.067)HQLPR;S(0.497)S(0.497)LGS(0.006)HQLPR;S(0.499)S(0.499)LGS(0.001)HQLPR 118.87 0.00047461 17685700.0 41433.7 63708.8 111230.0 106823.0 151024.0 119441.0 120939.0 111795.0 120076.0 79010.1 True False 48447.607057122485 70033.38862720883 113882.14504212402 100838.05363483893 121431.93133485493 113177.30369613647 109482.78239746418 108860.4997065935 121831.88433852642 93334.00568639237 0.5190777648599936 0.7503523299163335 1.220157049990703 1.0803999345496924 1.3010470346989416 1.212605232828201 1.1730213612103249 1.1663540946948217 1.3053322145830595 1.0 16.51011519371015 -5.099988543299327 2.630085392515757 1.1926160157680126 0.52312789771857 0.8602182524638702 0.09020848638980923 0.09445478542820507 1.184919942887351 0.02272291762499335 0.09988670746779031 7.943491894018925e-06 5.099988543299327 -0.6694881180494425 S(ph)SLGSLQTPEAVTTR ddPTM_PC-9_AZD4547_30min_R2 1 SSLGSLQTPEAVTTR 15 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 S(0.556)S(0.415)LGS(0.027)LQT(0.002)PEAVTTR 94.454 0.0030295 9854600.0 17240.0 16190.0 21417.0 39488.0 39088.0 34333.0 24810.0 41957.0 23875.0 29896.0 True False 22721.961385723404 21423.100887294284 21132.996586380785 30384.651683518357 33661.305907992886 32186.152082537123 27018.041936661462 35473.50972594427 25136.983758221453 28849.350139634196 0.7876073906603261 0.74258521538974 0.7325293805265849 1.0532178900548235 1.1667959848339136 1.1156629846687158 0.9365216826684487 1.2296120901943501 0.8713188906008468 1.0 14.81625120064251 -5.7655769697226615 22.035262851552925 1.0653327599021096 0.7530749339034427 0.6509019714552278 0.10009449587001233 12.671203108498155 67485.64698747176 0.026468239968355123 0.04105084396534284 1.7156276236306866e-06 5.7655769697226615 -0.3122578259986669 S(ph)SLGSLQTPEAVTTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSLGSLQTPEAVTTR 15 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 S(0.986)S(0.014)LGSLQTPEAVTTR;S(0.989)S(0.011)LGSLQTPEAVTTR;S(0.86)S(0.134)LGS(0.004)LQT(0.001)PEAVT(0.001)T(0.001)R 213.02 1.4197000000000002e-17 34008000.0 60924.0 76562.0 70869.0 69659.0 86845.0 63896.0 55965.0 68142.0 59005.0 41626.0 True False 71237.22989615034 84162.56937936935 72558.78573217931 65756.23206752507 69828.34567204867 60545.181277520634 50663.590048487815 66353.3447024171 59867.836498507044 49172.46428876532 1.4487219814286645 1.7115792465702884 1.4755979140292383 1.3372572031649983 1.4200700876405479 1.2312822257995661 1.0303244057683556 1.3494004350230864 1.2175073461222758 1.0 15.585563037496147 -6.2077959376978065 0.798040170161349 1.1608868144507702 1.5991101077482446 0.6444776101697932 0.12072265630462951 0.4575993873478486 0.6202656396210877 0.0657636247261092 0.12075788143989612 6.197322007499899e-07 6.2077959376978065 0.43822329329747434 S(ph)SLGSLQTPEAVTTR ddPTM_PC-9_Lapatinib_30min_R1 1 SSLGSLQTPEAVTTR 15 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 S(0.5)S(0.5)LGSLQTPEAVTTR 189.52 2.0019000000000002e-07 15669000.0 31425.0 29710.0 27464.0 28177.0 24052.0 21001.0 22049.0 17917.0 26741.0 24996.0 True False 30976.873737360806 29641.208320376958 25206.015934105784 30249.23057571653 22637.3086480514 20102.836185722088 23190.589333414424 18749.48922922428 23729.14698478633 29316.525294923587 1.0566352398769687 1.01107508554261 0.8597886577803416 1.03181500097334 0.7721688849657516 0.6857168775456166 0.7910415405685911 0.6395535978634862 0.8094119867914646 1.0 14.839426499499796 -6.2724047722899785 22.550197095887345 0.7604994746804281 0.9820575431492893 0.48663368548358255 0.10240684066487184 148.34773560485172 305074.38249491877 0.030189544657178078 0.034639129900526484 5.340663654178435e-07 6.2724047722899785 0.22155806846886117 S(ph)SLLPTDYLVEINK ddPTM_PC-9_AZD4547_30min_R2 1 SSLLPTDYLVEINK 14 0 P46939;P46939-2 P46939 UTRN Utrophin 1 S(0.911)S(0.089)LLPTDYLVEINK 180.85 8.231799999999999e-27 0.0 2871.3 3112.6 2829.0 4231.7 3688.8 4714.8 4674.6 4261.8 3153.7 3565.2 True False 3784.3136732498615 4118.687079789508 2791.4856115642356 3256.1469441132663 3176.673793322866 4419.982810670379 5090.630344099869 3603.236736421322 3320.3981435938463 3440.3834331624216 1.0999685781451682 1.1971593166298866 0.8113879356168986 0.9464488500690739 0.9233487647633647 1.284735523391212 1.479669473765757 1.0473358003323496 0.9651244426967014 1.0 11.748353647930973 -6.754658636111264 24.999634088766452 1.178600065943516 0.9938853528636273 0.17406148191330217 0.17020946548847135 274.67281870748496 1012678.5617080868 0.06115335181420826 0.059837067431480366 1.7593059192138067e-07 6.754658636111264 -0.18471471307988874 S(ph)SLPNGEGLQLK ddPTM_PC-9_AZD4547_30min_R2 1 SSLPNGEGLQLK 12 0 Q9ULR3 Q9ULR3 PPM1H Protein phosphatase 1H 1 S(0.609)S(0.391)LPNGEGLQLK 130.66 0.00013949 6737500.0 42315.0 44784.0 51773.0 51267.0 52365.0 63996.0 53125.0 62951.0 57293.0 41704.0 True False 55770.2897933228 59259.55220114808 51086.45619212273 39448.18521725426 45095.02363569504 59994.3200033218 57853.02208323822 53223.36942007097 60321.39101402227 40243.955653709665 1.385805368468592 1.4725081378943814 1.2694193540940752 0.9802263365136659 1.1205415298567503 1.490765980351426 1.437558041785223 1.3225183398482567 1.4988931886585528 1.0 15.296484496857778 -6.763873573433265 24.99827496120201 1.3755801705266217 1.244869787599842 0.06673139090455615 0.18274835924891636 164.52470758703805 1689592.7406159013 0.06583217688179835 0.060789481827265665 1.7223698975449727e-07 6.763873573433265 -0.13071038292677972 S(ph)SLPNGEGLQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSLPNGEGLQLK 12 0 Q9ULR3 Q9ULR3 PPM1H Protein phosphatase 1H 1 S(0.968)S(0.032)LPNGEGLQLK 82.774 0.011746 5819400.0 35703.0 57350.0 38775.0 37882.0 34065.0 31379.0 38454.0 33323.0 27343.0 23757.0 True False 41746.812733606785 63043.328987053996 39699.54305500638 35759.59435510108 27390.207787648596 29733.430000427565 34811.358737149145 32448.306558637 27742.83964712614 28063.95603969148 1.487559796436516 2.246416324836399 1.4146096508581483 1.2742178723671562 0.9759923992508402 1.0594881904167364 1.2404294921184549 1.1562271018649202 0.9885576932877469 1.0 14.776430772561296 -5.579259564133934 2.7491522125417447 1.099422200528725 1.8681876370053976 0.6968640478017181 0.19975247737221047 0.13156877654453947 1.9992204324650473 0.05299523447266599 0.1106522160504167 2.634756204351153e-06 5.579259564133934 0.7687654364766725 S(ph)SLPNGEGLQLK ddPTM_PC-9_Lapatinib_30min_R1 1 SSLPNGEGLQLK 12 0 Q9ULR3 Q9ULR3 PPM1H Protein phosphatase 1H 1 S(0.879)S(0.121)LPNGEGLQLK 111.72 0.0020050999999999997 0.0 32108.0 50518.0 47643.0 54394.0 52558.0 52165.0 55087.0 66159.0 57940.0 44369.0 True False 31650.134032113932 50401.02867481669 43725.976447298366 58394.31621306475 49466.6417730037 49934.02455255428 57939.135317238884 69232.98866530391 51414.18706475148 52038.122532023706 0.6082105289758826 0.9685404895958811 0.8402681403501802 1.1221449462772126 0.9505846745828014 0.9595662203574967 1.1133978802095283 1.3304282571435715 0.98801003116728 1.0 15.66728129197795 -4.116377657317108 0.563875445473816 1.097460796079088 3.803748520821601e-14 0.5288745272235792 0.12274072891270603 6.3437653831271215 0.8811773165398208 0.06379740993865529 5.364837188372055 7.649311425877417e-05 4.116377657317108 -1.0974607960790501 S(ph)SLQQENLVEQAGSSSLVNGR ddPTM_PC-9_Lapatinib_30min_R1 1 SSLQQENLVEQAGSSSLVNGR 21 0 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 S(0.5)S(0.5)LQQENLVEQAGSSSLVNGR 88.561 0.00043556 3712900.0 4161.8 3048.3 5222.5 1497.9 4732.4 4833.7 3228.4 3246.4 6454.6 3115.6 True False 4102.451968819354 3041.2418486369947 4793.126209432989 1608.0605628479195 4454.049536256379 4626.973918905044 3395.5507553174803 3397.2395955658667 5727.614978048761 3654.127308723955 1.1226899399550359 0.8322758326936934 1.3117020301919309 0.440066923505592 1.2189092387730087 1.2662322705228388 0.9292371251573138 0.9296992985042453 1.567437172857801 1.0 11.835311182575275 S(ph)SLRCCRIRFT(ph)WALALLQ ddPTM_PC-9_AZD4547_30min_R2 1 SSLRCCRIRFTWALALLQ 18 3 A0A1B0GV41 A0A1B0GV41 2 S(0.5)S(0.5)LRCCRIRFT(1)WALALLQ 44.733999999999995 0.040413 4939400.0 22296.0 17296.0 34613.0 50401.0 39038.0 33406.0 19059.0 27835.0 19292.0 26037.0 True False 29385.664214390315 22886.593758285468 34154.00900426758 38781.82813768761 33618.24754493006 31317.117539080045 20755.214077824705 23533.740334667847 20311.735734601403 25125.452555046017 1.1695576089628965 0.9108927971802477 1.3593390578514508 1.5435275465276723 1.3380156027549208 1.2464299884935024 0.8260632930831081 0.9366494109154463 0.8084127316752405 1.0 14.616861961633678 -7.252882739286859 22.097571446389704 0.8875021320244245 1.266139324725743 0.5639468085714616 0.1586865771050124 106.25624215022985 274408.3250983252 0.06869864924419644 0.0521640171838197 5.586210035949012e-08 7.252882739286859 0.37863719270131857 S(ph)SLSASHPMVGK ddPTM_PC-9_AZD4547_30min_R2 2 SSLSASHPMVGK 12 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q8TEW0-6;Q8TEW0-7;Q8TEW0-8;Q5VWU8;Q8TEW0-9;Q8TEW0-10 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.5)S(0.5)LSAS(0.001)HPMVGK;S(0.486)S(0.486)LS(0.024)AS(0.004)HPMVGK 89.44 0.0051937 105542000.0 92007.0 67362.0 224433.0 334668.0 267496.0 242422.0 180321.0 283978.0 184017.0 273505.0 True False 121263.31213551374 89135.44916429376 221456.87177808303 257515.4631690572 230358.79771706084 227263.3140172088 196369.2196719356 240095.72526525278 193743.7629418489 263929.67319844355 0.45945312122725296 0.33772424329595774 0.8390753078058562 0.975697275900601 0.8728037091299642 0.8610752677526106 0.7440210010955813 0.9096958381209737 0.7340734393141796 1.0 18.00979403415615 -5.26834798024897 23.284847385265145 0.8633078542299455 0.39858865042900987 0.8288368920362675 0.08514117354765811 67.16375249675558 226372.04239977477 0.021489171245351518 0.04651129587071154 5.390785105374078e-06 5.26834798024897 -0.4647192038009356 S(ph)SLSASHPMVGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSLSASHPMVGK 12 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q8TEW0-6;Q8TEW0-7;Q8TEW0-8;Q5VWU8;Q8TEW0-9;Q8TEW0-10 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.496)S(0.496)LS(0.004)AS(0.004)HPMVGK;S(0.403)S(0.403)LS(0.107)AS(0.088)HPMVGK 82.774 0.0081447 51028000.0 43970.0 54927.0 110589.0 114953.0 120616.0 99010.0 103279.0 95378.0 100079.0 69408.0 True False 51413.25255291401 60379.78956010313 113225.86117111803 108512.55609265438 96982.16064920052 93817.74130285635 93495.66544479165 92874.42856134458 101542.4660441334 81991.12096657426 0.6270587832781785 0.7364186371438739 1.3809527158102568 1.3234671609977409 1.1828373548977058 1.1442426960000156 1.1403145162865562 1.1327376363009742 1.2384568578533002 1.0 16.32318006451107 -5.161876428506247 5.583411831283831 1.1974945337263774 0.6591108161629592 0.8017650622784834 0.10197252286995724 0.09153483405427221 4.128201586133083 0.02692126579753633 0.07465614339059179 6.8884826913286354e-06 5.161876428506247 -0.5383837175634182 S(ph)SLSGDEEDELFK ddPTM_PC-9_Lapatinib_30min_R1 4 SSLSGDEEDELFK 13 0 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 1 S(0.5)S(0.5)LSGDEEDELFK;S(0.715)S(0.065)LS(0.219)GDEEDELFK;S(0.922)S(0.078)LSGDEEDELFK;S(0.83)S(0.17)LSGDEEDELFK 188.96 2.5410999999999998e-05 20129760.0 129719.0 142295.0 135703.0 126058.0 138268.0 141865.0 126673.0 137484.0 145607.0 132442.0 True False 127869.18327244857 141965.52467007865 124546.02316872879 135328.72583716077 130135.34808534705 135797.76465346722 133231.5081242509 143872.00855001755 129207.2063503154 155334.4232321276 0.8231863910896575 0.9139347333071768 0.8017928066247786 0.8712088603498348 0.8377753325859799 0.8742284023582763 0.8577075534967115 0.9262081485635614 0.8318002131261764 1.0 17.24501805125231 -14.522878741373564 0.2411976487677354 1.7982259765301116 0.8481278412129426 0.5699888974360383 0.03672110206039111 118.29148048941275 1.1768318733067658 46.308762669398 0.05297618531654905 3.000000026987037e-15 14.522878741373564 -0.950098135317169 S(ph)SLVTSK ddPTM_PC-9_Lapatinib_30min_R1 4 SSLVTSK 7 0 A6NMQ3;Q5T5H1;O43768-2;O43768;O43768-9;O43768-3;O43768-4;A0A1W2PRU0;O43768-6;O43768-5;O43768-7 A6NMQ3 ENSA Alpha-endosulfine 1 S(0.915)S(0.085)LVTSK;S(0.649)S(0.351)LVTSK;S(0.5)S(0.5)LVTSK;S(0.5)S(0.5)LVTSK 106.68 0.010019 448313000.0 1775870.0 1544180.0 1600660.0 1429340.0 1149650.0 834130.0 898500.0 810600.0 1015790.0 1236080.0 True False 1750545.7681453298 1540604.54608414 1469059.9135262778 1534458.431738461 1082029.8472988636 798456.2043520006 945019.9336057354 848263.4352407894 901381.0334570914 1449734.7810269292 1.20749380580172 1.0626802683128307 1.013330115792393 1.058440793323257 0.7463639980634256 0.5507601906235629 0.6518571161935732 0.5851162890911098 0.6217558171699462 1.0 20.46735756260243 -6.310569507214676 3.1578363084482652 0.6529006977439177 1.0856630139077497 0.7005329610154551 0.12568123259782918 0.13077501472077893 2.620327797125126 0.03860085202068114 0.04633398126431969 4.891369743181348e-07 6.310569507214676 0.432762316163832 S(ph)SLYFPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSLYFPR 7 0 B8ZZW8;E7ENZ2;E9PG19;O94868-2;O94868 B8ZZW8 FCHSD2 F-BAR and double SH3 domains protein 2 1 S(0.639)S(0.209)LY(0.152)FPR 95.90899999999999 0.014555000000000002 0.0 14373.0 14462.0 14695.0 15726.0 18417.0 14397.0 15782.0 12401.0 13061.0 10383.0 True False 16806.065020310063 15897.691783971666 15045.384531097834 14844.923204379895 14808.321057540712 13641.995975529986 14287.014708214685 12075.486889945609 13251.992416015604 12265.355708217223 1.3702060845288633 1.2961460036027284 1.2266570076739087 1.2103133050136068 1.2073291154222148 1.1122381038154872 1.1648267729115303 0.9845199093456042 1.0804409371623345 1.0 13.582301453725401 -4.883039052092246 0.24556265470826694 0.9736223690624682 1.6589635802910112 0.8794676859837814 0.04058963594963386 3.0730124707638096 0.1668260618161536 0.06105157785072918 0.6421677769166759 1.3090642056514656e-05 4.883039052092246 0.685341211228543 S(ph)SLYGIAK ddPTM_PC-9_AZD4547_30min_R2 1 SSLYGIAK 8 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 S(0.938)S(0.062)LYGIAK 111.61 0.0037431999999999995 6397400.0 49821.0 37662.0 49149.0 74177.0 81048.0 69418.0 51777.0 95167.0 66942.0 59530.0 True False 65663.04165882402 49835.504979448866 48497.252146613864 57076.638673225825 69795.88419031425 65077.281486195796 56385.05269466021 80461.12687010363 70480.41745519832 57445.87281952179 1.1430419355820074 0.8675210686765525 0.8442251769588063 0.9935724860956331 1.21498518108677 1.1328452035301069 0.9815335711201679 1.4006424294899142 1.2269013246021567 1.0 15.80991562617724 -6.145555351032286 4.652687821920836 1.1687870576041839 0.9401061716137032 0.3409045705031688 0.13430586323331817 0.248843875055989 8.4582654406442 0.0409574087488654 0.053703147479715226 7.152282320976529e-07 6.145555351032286 -0.22868088599048064 S(ph)SLYGIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSLYGIAK 8 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 S(0.5)S(0.5)LYGIAK;S(0.935)S(0.065)LYGIAK 120.99 0.0033918 13961300.0 163867.0 149015.0 140610.0 140313.0 175146.0 124386.0 107424.0 140689.0 94575.0 81983.0 True False 191606.44657922178 163808.22439417333 143962.6756663945 132451.71751088352 140827.39859608116 117862.97919096166 97248.0210375904 136996.06282231727 95957.98045667836 96845.868922929 1.9784679378704761 1.6914322336715641 1.486513335751694 1.3676548001886384 1.4541394502655878 1.2170160741162672 1.004152496323632 1.4145782814065122 0.9908319427960605 1.0 16.563402889797544 -1.5228787452878627 0.28205612214195735 1.043788770832323 8.18605295850235 0.8373936832593583 0.12318514676858688 19.85424459397093 0.28029378944342564 0.133539473365893 70.05733259957837 0.029999999999480182 1.5228787452878627 7.142264187670026 S(ph)SLYGIAK ddPTM_PC-9_Lapatinib_30min_R1 1 SSLYGIAK 8 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 S(0.92)S(0.08)LYGIAK 108.57 0.0037919000000000004 7069600.0 75763.0 64974.0 71911.0 77841.0 45521.0 54897.0 46051.0 49809.0 66172.0 66913.0 True False 74682.60572676729 64823.55669499063 65998.75516448735 83565.68680996368 42843.54427772938 52549.18328115731 48435.29545072648 52123.3079766943 58719.01253794845 78478.8228940319 0.9516274960903714 0.8260006241750127 0.8409753450762623 1.0648183003814986 0.5459249093934552 0.6695969860826434 0.6171766301353362 0.6641703590161536 0.748214745998871 1.0 16.260015782247294 -6.264245932597125 24.997841845768907 0.6843097461286195 0.9083743742708282 0.388748371207734 0.12872338596957997 239.5188085411245 2133379.130275935 0.03752402814303018 0.04447828641356966 5.44194398768991e-07 6.264245932597125 0.22406462814220873 S(ph)SMEMEGIFNHK ddPTM_PC-9_AZD4547_30min_R2 3 SSMEMEGIFNHK 12 0 E7EPJ7;O75962-4;O75962;O75962-5;O75962-2;E7EWP2 E7EPJ7 TRIO Triple functional domain protein 1 S(0.5)S(0.5)MEMEGIFNHK;S(0.5)S(0.5)MEMEGIFNHK;S(0.5)S(0.5)MEMEGIFNHK 91.712 0.0043377 104495600.0 167006.0 158511.0 219466.0 269208.0 212996.0 260869.0 174680.0 254704.0 203787.0 180997.0 True False 220110.43405940363 209746.5808984498 216555.73744346277 207146.25482213878 183425.18197858328 244556.82019105228 190226.1816000014 215345.34931565454 214558.76478059404 174660.3501211993 1.2602198146669572 1.2008826316499635 1.2398677621634886 1.1859947302200933 1.050182149819933 1.4001851022361447 1.0891205787003218 1.2329378085308047 1.2284342990936905 1.0 17.41419261173639 -10.800736237556992 3.0478774187638713 0.9987184281227772 1.2077248650094574 0.32732883466681617 0.090166569254632 30640436.179710116 39905455.46107819 367899.5355443008 0.02079048480041735 1.582208678976248e-11 10.800736237556992 0.2090064368866802 S(ph)SMEMEGIFNHK ddPTM_PC-9_Lapatinib_30min_R1 4 SSMEMEGIFNHK 12 0 E7EPJ7;O75962-4;O75962;O75962-5;O75962-2;E7EWP2 E7EPJ7 TRIO Triple functional domain protein 1 S(0.5)S(0.5)MEMEGIFNHK;S(0.5)S(0.5)MEMEGIFNHK;S(0.633)S(0.367)MEMEGIFNHK;S(0.5)S(0.5)MEMEGIFNHK 88.28200000000001 0.0041283000000000005 158492300.0 357795.0 440745.0 392453.0 345399.0 424740.0 451721.0 415662.0 390446.0 435396.0 344779.0 True False 352692.7776884323 439724.4820317924 360187.0292523902 370800.7946772863 399757.6282709686 432401.94584308227 437182.94451021426 408587.5465532006 386357.11755686085 404373.5907608605 0.872195380081111 1.0874213649917555 0.8907283697104704 0.9169757945359281 0.9885849061477864 1.0693130207377892 1.081136242571184 1.010420947086112 0.9554459697278939 1.0 18.625329253768577 -6.522197057006768 9.256542639596564 1.0277369533090333 0.9490603678097039 0.2633559052849853 0.06352919583379674 0.147056792646741 199.3564580433908 0.02069270684797091 0.021549488498183993 3.0047126333841096e-07 6.522197057006768 -0.07867658549932932 S(ph)SMSGLHLVK ddPTM_PC-9_AZD4547_30min_R2 1 SSMSGLHLVK 10 0 A0A0C4DGT1;Q13085;Q13085-2;Q13085-4 A0A0C4DGT1 ACACA Acetyl-CoA carboxylase 1;Biotin carboxylase 1 S(0.463)S(0.463)MS(0.074)GLHLVK 58.132 0.04434 5927100.0 27319.0 31826.0 77869.0 99356.0 85872.0 79982.0 58394.0 78200.0 60671.0 64516.0 True False 36005.873729499865 42113.13210864905 76836.40618129926 76451.00923489788 73950.15505861543 74980.71289620717 63590.95287583272 66115.98685723102 63877.945197698675 62257.31447714204 0.5783396542541123 0.6764366960304883 1.234174760453408 1.2279843722293402 1.187814727950825 1.204367928907961 1.0214213929703044 1.0619794222172192 1.0260311697375197 1.0 15.925955725806096 -5.195406653094695 5.528001188772578 1.1281352476543531 0.6116806971645317 0.8356441731929249 0.08756700336449509 0.08352763220418474 4.979690642868806 0.024319022306930914 0.06672441278385857 6.376661257484766e-06 5.195406653094695 -0.5164545504898215 S(ph)SMSGLHLVK ddPTM_PC-9_Lapatinib_30min_R1 1 SSMSGLHLVK 10 0 A0A0C4DGT1;Q13085;Q13085-2;Q13085-4 A0A0C4DGT1 ACACA Acetyl-CoA carboxylase 1;Biotin carboxylase 1 S(0.479)S(0.479)MS(0.042)GLHLVK 64.64 0.028839999999999998 4252400.0 79648.0 59369.0 95409.0 69381.0 71730.0 79775.0 70985.0 90792.0 89595.0 49138.0 True False 78512.20491434554 59231.53472812049 87564.84030939055 74483.51018823116 67510.982426606 76363.20921460786 74660.25596772744 95010.52777249145 79503.86762282382 57631.43782773066 1.3623155672261855 1.0277643064393565 1.5193936436417825 1.2924111040032347 1.1714263077802576 1.3250269660609437 1.2954779332575141 1.648588536980332 1.3795225422012418 1.0 15.814568393045699 -7.556825518151562 24.999444238700605 1.4028399293207419 1.2802710981925187 0.0 0.19101945182653077 502.21046711476936 369837.7676594496 0.0855021669298608 0.04936490775816171 2.774434535656192e-08 7.556825518151562 -0.12256883112822314 S(ph)SPAAFINPPIGTVTPALK ddPTM_PC-9_AZD4547_30min_R2 2 SSPAAFINPPIGTVTPALK 19 0 Q6R954;F8WEE2;Q8WUT1;F8WCX5;F6VRR5;Q9BY77-2;Q9BY77 Q6R954 PDIP46;POLDIP3 Polymerase delta-interacting protein 3 1 S(0.5)S(0.5)PAAFINPPIGTVTPALK;S(0.5)S(0.5)PAAFINPPIGTVTPALK 199.65 4.133e-15 18865800.0 42089.0 34256.0 50128.0 70331.0 58085.0 55689.0 45305.0 59054.0 50651.0 58756.0 True False 55472.42649441485 45328.58208740908 49463.269966946646 54117.27455311819 50020.90037008202 52206.75802651709 49337.05723258553 49928.56122591974 53328.30845393407 56698.970323934554 0.9783674408457126 0.7994604104525396 0.8723839195729896 0.9544666198333669 0.8822188495540721 0.9207708310794288 0.8701579049974156 0.8805902636444034 0.9405516211186359 1.0 15.791034915033674 -8.544371329384617 3.2750814179272494 0.9997811200181483 0.8927099247144312 0.33059884620833413 0.04675663115625201 0.2597216341209626 7.490041378047349 0.0436076417513974 0.011554693785573767 2.855148297666696e-09 8.544371329384617 -0.10707119530371711 S(ph)SPAAFINPPIGTVTPALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPAAFINPPIGTVTPALK 19 0 Q6R954;F8WEE2;Q8WUT1;F8WCX5;F6VRR5;Q9BY77-2;Q9BY77 Q6R954 PDIP46;POLDIP3 Polymerase delta-interacting protein 3 1 S(0.5)S(0.5)PAAFINPPIGTVTPALK;S(0.5)S(0.5)PAAFINPPIGTVTPALK 274.08 9.763699999999998e-92 15512100.0 56464.0 59293.0 63980.0 66090.0 74587.0 63326.0 68562.0 54620.0 61555.0 47786.0 True False 66022.23998516572 65179.21718621433 65505.525845501164 62387.191566670925 59972.21277725951 60005.07308094828 62067.31101410561 53186.28287467375 62455.12542438102 56449.22352623214 1.1695863266300726 1.1546521478001435 1.1604327172907973 1.1051913147694474 1.0624098797282877 1.062992001175423 1.0995246194177095 0.942196890448952 1.1063947654719806 1.0 15.784666116038272 -6.082852569919367 0.5602868699401268 1.0207470066266557 1.194328234149109 0.5946388381722748 0.04381876349022986 0.8226200646014467 0.4885259597690765 0.030370895952070504 0.07868279002478235 8.263184125343569e-07 6.082852569919367 0.1735812275224533 S(ph)SPAAFINPPIGTVTPALK ddPTM_PC-9_Lapatinib_30min_R1 2 SSPAAFINPPIGTVTPALK 19 0 Q6R954;F8WEE2;Q8WUT1;F8WCX5;F6VRR5;Q9BY77-2;Q9BY77 Q6R954 PDIP46;POLDIP3 Polymerase delta-interacting protein 3 1 S(0.5)S(0.5)PAAFINPPIGTVTPALK;S(0.5)S(0.5)PAAFINPPIGTVTPALK 265.29 2.3385e-78 12174400.0 56633.0 54951.0 57576.0 41763.0 47182.0 51168.0 43984.0 46086.0 52424.0 41277.0 True False 55825.403034779774 54823.76433567936 52842.323529787194 44834.39033728398 44406.84752338103 48979.66391843379 46261.27630463517 48227.32380521459 46519.45707080659 48411.67445185474 1.1531392720220401 1.1324492481705302 1.0915202609308363 0.9261069947471376 0.9172755957355596 1.0117324895907889 0.9555810004184396 0.9961920208559717 0.9609140274020069 1.0 15.563067374215256 -5.623021991795046 4.447079295566234 0.9663527522577786 1.1365135799787673 0.860138286747756 0.029737219199832333 0.07351586340301332 2.541922928667372 0.0085964929207399 0.015464015253829221 2.3821988365687067e-06 5.623021991795046 0.17016082772098873 S(ph)SPAELSSSSQHLLR ddPTM_PC-9_AZD4547_30min_R2 1 SSPAELSSSSQHLLR 15 0 Q9UQC2-2;Q9UQC2;E9PJE2 Q9UQC2-2 GAB2 GRB2-associated-binding protein 2 1 S(0.5)S(0.5)PAELSSSSQHLLR 110.32 0.00030558 8808200.0 3218.1 7247.1 33443.0 66304.0 41820.0 35669.0 14594.0 55175.0 25797.0 40427.0 True False 4241.388859361747 9589.583350235354 32999.523968731984 51018.6371865884 36014.01486574557 33438.611791338255 15892.837727675833 46648.97154536731 27160.57675438071 39011.663035021105 0.10872104723026586 0.24581324158436166 0.845888675371466 1.3077790900836124 0.9231602055368796 0.8571439715687108 0.40738682976443985 1.1957698779334305 0.6962168398204001 1.0 15.251617880122588 -5.245057804599801 4.099789800207998 0.9106064039054674 0.14881721533882988 0.6076478012851867 0.23503321701905455 0.13749053896109492 5.547838683706938 0.06284137391720683 0.1688070919796816 5.687772215517321e-06 5.245057804599801 -0.7617891885666376 S(ph)SPAELSSSSQHLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPAELSSSSQHLLR 15 0 Q9UQC2-2;Q9UQC2;E9PJE2 Q9UQC2-2 GAB2 GRB2-associated-binding protein 2 1 S(0.5)S(0.5)PAELSSSSQHLLR 82.925 0.0041356000000000006 3736200.0 12443.0 27779.0 19636.0 16444.0 23103.0 18467.0 22485.0 13841.0 16108.0 18714.0 True False 14549.354139547631 30536.715534984705 20104.19670994469 15522.695992167315 18576.132996273183 17498.558010704466 20355.05802269719 13477.688415751723 16343.549026657938 22106.700060057505 0.6581422871808659 1.3813330552287446 0.9094164509097877 0.7021715565867652 0.8402942522315501 0.7915499809182713 0.9207642012330375 0.609665322238812 0.7393029706947326 1.0 14.432196064934105 -5.519586708451074 24.527115028044566 0.7917348373273996 1.0511469311477375 0.16953314207369952 0.19229574166334218 131.83708470872446 982241.4784255804 0.04850983670814846 0.08631831848500753 3.0228269920085624e-06 5.519586708451074 0.2594120938203379 S(ph)SPAPHSGPCPSR ddPTM_PC-9_AZD4547_30min_R2 2 SSPAPHSGPCPSR 13 0 P85299;P85299-5;P85299-2;P85299-4;P85299-3 P85299 PRR5 Proline-rich protein 5 1 S(0.5)S(0.5)PAPHSGPCPSR;S(0.654)S(0.346)PAPHSGPCPSR 121.92 0.00010755 11187000.0 20837.6 17065.7 33208.8 49996.0 38235.0 31533.3 29638.7 46518.0 32042.7 41071.9 True False 27463.52335099476 22581.85378704745 32768.42961375554 38470.194630499995 32926.73023414112 29561.517766122037 32276.486882230063 39329.71197729761 33736.411705531435 39633.985282313384 0.6929286357496409 0.569759857006471 0.8267760453647444 0.9706365473084856 0.8307701080172382 0.745862863791137 0.8143639013923085 0.9923229192611231 0.8511990773884216 1.0 15.274450420232982 -3.6076315062418445 0.37749134755741653 0.9164406499108964 2.7622698130840474e-35 0.46793290081590455 0.09491607403351761 13.938088865550522 0.7882976926200397 0.08304197638067326 6.9218506152374895 0.00024681326305393104 3.6076315062418445 -0.9164406499108964 S(ph)SPAPHSGPCPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSPAPHSGPCPSR 13 0 P85299;P85299-5;P85299-2;P85299-4;P85299-3 P85299 PRR5 Proline-rich protein 5 1 S(0.816)S(0.184)PAPHSGPCPSR;S(0.5)S(0.5)PAPHSGPCPSR;S(0.5)S(0.5)PAPHSGPCPSR;S(0.5)S(0.5)PAPHSGPCPSR 109.55 0.00043876 16103200.0 27483.0 31394.7 53301.8 55433.8 67003.0 56221.9 57360.2 51628.0 49114.7 39225.1 True False 32135.329086007187 34511.35833565589 54572.717060202165 52328.02390480447 53874.24313506003 53273.52459100154 51926.62660411459 50272.819704387686 49832.90957161636 46336.30012427925 0.6935238463109173 0.7448017697376027 1.1777530125157145 1.1293094995598425 1.1626790009250447 1.1497146826163473 1.1206468031509085 1.0849554144277864 1.0754615590359782 1.0 15.499855231575761 -5.2428682566580385 10.157738211941838 1.1196127352213203 0.7186136343339182 0.9081435181422288 0.050006611305237196 0.11847789157838307 62.392315370107674 0.01252832516791614 0.03189250831365595 5.716520211589856e-06 5.2428682566580385 -0.4009991008874021 S(ph)SPAPHSGPCPSR ddPTM_PC-9_Lapatinib_30min_R1 3 SSPAPHSGPCPSR 13 0 P85299;P85299-5;P85299-2;P85299-4;P85299-3 P85299 PRR5 Proline-rich protein 5 1 S(0.5)S(0.5)PAPHSGPCPSR;S(0.5)S(0.5)PAPHSGPCPSR;S(0.5)S(0.5)PAPHSGPCPSR 98.654 0.0015328 12844100.0 48778.0 37979.9 64152.0 50410.5 60159.0 60173.0 41211.5 49958.1 71253.0 42823.8 True False 48082.41677521034 37891.959875028086 58877.67019388128 54117.856334498276 56620.5658971447 57599.54106011403 43345.22982058182 52279.33570701058 63227.73681264644 50225.83677087329 0.9573243546853967 0.7544316294398145 1.1722586218419224 1.0774903876938895 1.1273195139673573 1.1468109794343309 0.8630066238282836 1.0408853105923392 1.2588687591425685 1.0 15.61614207424984 -5.263261083740783 24.999992066852386 1.0826940510870153 0.8558779891854688 0.40804951787359867 0.11073410828689519 149.4742200158619 2051328.070347185 0.028880757050962075 0.06557208381528036 5.454298677855268e-06 5.263261083740783 -0.22681606190154657 S(ph)SPELEDTATSSK ddPTM_PC-9_AZD4547_30min_R2 2 SSPELEDTATSSK 13 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(0.705)S(0.295)PELEDTATSSK;S(0.884)S(0.116)PELEDTATSSK 168.0 0.00016307 16630000.0 59142.0 131638.0 77812.0 71887.0 71195.0 79943.0 69463.0 80485.0 58681.0 63819.0 True False 77947.92576997976 174187.4091786068 76780.16203854232 55314.562793078585 61310.803165154386 74944.15157237236 75645.0724323384 68047.89261130734 61782.75786036412 61584.7162349918 1.2657024426734398 2.8284194492989365 1.2467405345438065 0.8981865335225726 0.9955522557124039 1.2169277728974883 1.228309182162922 1.1049477333248348 1.003215759322762 1.0 15.91028473456282 -5.461523741738368 11.020771363321698 1.0781253095609715 2.0461981013464685 0.5335138157544908 0.3625615225995039 0.5637729864808382 99.84331901345416 0.08656306421851687 0.18008507064979412 3.4552244025746943e-06 5.461523741738368 0.968072791785497 S(ph)SPELEDTATSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPELEDTATSSK 13 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(0.916)S(0.084)PELEDTATSSK 193.11 1.4894999999999999e-06 6608400.0 59224.0 107260.0 68317.0 71369.0 80569.0 39214.0 81738.0 42147.0 48488.0 34868.0 True False 69249.45347268107 117908.06394335536 69945.93637366538 67370.42631141994 64782.08281940588 37157.54880769835 73995.18490812632 41040.685908437794 49197.04526971629 41189.29238506387 1.6812489232709524 2.8625901809886733 1.6981582426754505 1.6356296117349645 1.572789408805121 0.9021167069423238 1.7964665237841906 0.9963921090161781 1.1944134609012174 1.0 15.329981721066902 -5.859277126290281 1.2658809017661055 1.227118517034079 2.268440737684624 0.5127317808598981 0.3812684614842189 0.3616721099593366 1.166539510751421 0.13004108552795546 0.2910874030846452 1.3826837973879763e-06 5.859277126290281 1.041322220650545 S(ph)SPELEDTATSSK ddPTM_PC-9_Lapatinib_30min_R1 2 SSPELEDTATSSK 13 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(0.975)S(0.025)PELEDTATSSK;S(0.5)S(0.5)PELEDTATSSK 161.21 7.2653e-05 11915100.0 52544.0 157633.0 79462.0 35619.0 56477.0 81994.0 147624.0 140323.0 52438.0 41378.0 True False 51794.71292461053 157268.01047344244 72928.9410921903 38238.54008150076 53155.13389805418 78487.30775734954 155267.24839022045 146842.9188542968 46531.88024338005 48530.13216728072 1.0672691503513112 3.2406260492213 1.5027558721828373 0.7879339777953747 1.095301651246927 1.6172902123325787 3.1993988364800394 3.0258091683768193 0.9588245109860241 1.0 15.566593168702061 -7.0435970524478275 24.960893944653474 2.2424712848312436 1.5662776197446566 0.04790868905239576 0.9276279873294031 1127.0831016172954 645292.5298410234 0.3628069208340553 0.28104849446381974 9.044882877794452e-08 7.0435970524478275 -0.676193665086587 S(ph)SPELLPSGVTDENEVTTAVTEK ddPTM_PC-9_AZD4547_30min_R2 1 SSPELLPSGVTDENEVTTAVTEK 23 0 P42566;B1AUU8;P42566-2 P42566 EPS15 Epidermal growth factor receptor substrate 15 1 S(0.484)S(0.484)PELLPS(0.031)GVTDENEVTTAVTEK 146.25 6.2145e-07 3803200.0 54464.0 64186.0 70936.0 63543.0 64753.0 79601.0 72873.0 86565.0 72873.0 64224.0 True False 71782.41907842457 84932.86927435896 69995.34229124094 48894.143079563575 55763.163668140194 74623.53688643691 79358.55582629291 73188.36831580811 76724.91800682188 61975.53730826418 1.1582379467140607 1.3704257028366822 1.129402750364011 0.7889264894367239 0.89976087485577 1.2040805151113416 1.2804819332435344 1.1809234981178411 1.237987137169861 1.0 15.919411253624382 S(ph)SPELLPSGVTDENEVTTAVTEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPELLPSGVTDENEVTTAVTEK 23 0 P42566;B1AUU8;P42566-2 P42566 EPS15 Epidermal growth factor receptor substrate 15 1 S(0.5)S(0.5)PELLPSGVTDENEVTTAVTEK;S(0.5)S(0.5)PELLPSGVTDENEVTTAVTEK 132.77 1.0917e-08 7309300.0 104205.0 125927.0 117587.0 117277.0 130933.0 98709.0 124437.0 78504.0 97139.0 95727.0 True False 121844.84835743505 138428.20033744958 120390.72003118056 110706.3499071638 105277.61856040506 93532.52627273659 112649.4265141373 76443.35318186361 98559.47410606676 113081.54732548476 1.0774954114018862 1.224144907913305 1.0646362990122311 0.9789957117275343 0.9309884861884892 0.8271245705855098 0.9961786797088682 0.6760020090796535 0.8715787538914829 1.0 16.787004003641165 -5.917098147743144 1.2773889890551402 0.8608874087998558 1.158046988452856 0.5702575845555289 0.09375580682438904 0.30656630760714365 1.0129934229787751 0.032970552063121626 0.06826626860886792 1.2103245771166938e-06 5.917098147743144 0.2971595796530001 S(ph)SPELLPSGVTDENEVTTAVTEK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPELLPSGVTDENEVTTAVTEK 23 0 P42566;B1AUU8;P42566-2 P42566 EPS15 Epidermal growth factor receptor substrate 15 1 S(0.5)S(0.5)PELLPSGVTDENEVTTAVTEK 119.28 1.0917e-08 3337100.0 50252.0 67848.0 64105.0 60944.0 73611.0 65284.0 63750.0 70801.0 64963.0 60359.0 True False 49535.39726491182 67690.90212456869 58834.53435245603 65426.02506322418 69281.34570479426 62491.95550443699 67050.66306885447 74090.67293175802 57646.18284928292 70791.97272668808 0.6997318390343051 0.9561946011295387 0.8310904765940478 0.9242011847278134 0.9786610407407912 0.8827548251226789 0.9471506512146798 1.046597093964389 0.8143039475936332 1.0 16.11129815844575 -4.2937574488392825 2.08672968967228 0.9315972562707786 1.2643431279290908e-11 0.4851033438077845 0.07011990672729755 4.60728277108918 5.309764823522408 0.0178148124659986 13.619915224643702 5.0844332617572384e-05 4.2937574488392825 -0.9315972562581352 S(ph)SPELTR ddPTM_PC-9_AZD4547_30min_R2 2 SSPELTR 7 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.592)S(0.369)PELT(0.039)R;S(0.743)S(0.257)PELTR 96.66799999999999 0.012731000000000001 99422000.0 66553.0 60897.0 85792.0 107949.0 88094.0 96742.0 84897.0 89022.0 72277.0 84803.0 True False 87715.46961160391 80580.76434425937 84654.3420245031 83063.0258454245 75863.66871312736 90692.70744673663 92452.6685327185 75265.69542205146 76097.41466358001 81834.07278202448 1.0718697802716637 0.9846847603307799 1.034463263853319 1.015017620675846 0.9270425647175101 1.108251176601075 1.129757635049865 0.9197354214855133 0.9298989049008377 1.0 16.32041403443656 -7.799242683945613 24.99999297247288 0.9436127766423558 1.0339509073662747 0.3221970149960144 0.05855795384596548 212.57646680530226 140577.8007261892 0.033384976212028177 0.016038184075779966 1.5876593159548535e-08 7.799242683945613 0.09033813072391894 S(ph)SPELTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPELTR 7 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.649)S(0.351)PELTR 101.25 0.011258 71768000.0 58549.0 60018.0 63192.0 55333.0 63962.0 55047.0 57986.0 43160.0 46324.0 40859.0 True False 68460.18930453867 65976.19039485624 64698.736936994515 52232.87140200643 51429.10525505885 52160.23841529481 52493.146297714906 42027.09573180005 47001.400863602066 48266.413260333946 1.4183815344903672 1.3669171984875133 1.3404504823681378 1.0821784316203205 1.065525730649724 1.080673596646985 1.087570895616032 0.870731692970825 0.9737910420252527 1.0 15.55873200177864 -5.657021991901501 0.6852356286627176 0.9709883099407607 1.5100104754000105 0.8759620018832925 0.06128136659508439 0.42509199752825766 0.31467113675267616 0.034271441398430136 0.15196772957617208 2.202814913592883e-06 5.657021991901501 0.5390221654592499 S(ph)SPEQPIGQGR ddPTM_PC-9_AZD4547_30min_R2 3 SSPEQPIGQGR 11 0 Q8N201 Q8N201 INTS1 Integrator complex subunit 1 1 S(0.911)S(0.089)PEQPIGQGR;S(0.999)S(0.001)PEQPIGQGR;S(0.999)S(0.001)PEQPIGQGR 190.35 0.00050728 112548000.0 151798.0 148436.0 191633.0 264319.0 221780.0 186549.0 170347.0 222579.0 165964.0 193189.0 True False 200066.60640545483 196415.03417581314 189091.82120922202 203384.33823784176 190989.67520145985 174884.06153977828 185507.55299413382 188184.5299065936 174736.5182177786 186425.51191215543 1.0731718226404934 1.0535845237124242 1.0143022769240027 1.0909683774057566 1.024482503722211 0.938090821079169 0.99507600162335 1.0094355004119127 0.9372993879727967 1.0 17.508239777511797 -6.545580727966188 8.226381803268872 0.9780038099709679 1.0549965183119994 0.6442376755904577 0.02880417143761014 0.1297123048791077 38.699730046496256 0.009227644624014904 0.00932704623015102 2.8472085032905693e-07 6.545580727966188 0.07699270834103145 S(ph)SPEQPIGQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSPEQPIGQGR 11 0 Q8N201 Q8N201 INTS1 Integrator complex subunit 1 1 S(0.5)S(0.5)PEQPIGQGR;S(0.985)S(0.015)PEQPIGQGR;S(0.999)S(0.001)PEQPIGQGR 153.54 0.00043094 96730000.0 120547.0 125566.0 141488.0 153390.0 165121.0 125542.0 164583.0 140844.0 132835.0 111448.0 True False 140953.22618822203 138031.36264321578 144861.61051622813 144796.05559708952 132766.72538101644 118958.35651593989 148992.50676226712 137146.99423655315 134777.4605758694 131652.64017811752 1.0706448879226533 1.0484511549215287 1.1003319821025976 1.0998340435952505 1.0084623080964548 0.9035774470986446 1.1317092202685026 1.0417337172350065 1.023735341680381 1.0 17.00637692809336 -6.266850254240428 24.82129224409664 1.0202337230163523 1.0790406677351614 0.23882984826959985 0.05380506220871886 675.3698835139228 3098117.9626013543 0.01730239222049931 0.020152899889671495 5.409408084573965e-07 6.266850254240428 0.058806944718809095 S(ph)SPEQPIGQGR ddPTM_PC-9_Lapatinib_30min_R1 4 SSPEQPIGQGR 11 0 Q8N201 Q8N201 INTS1 Integrator complex subunit 1 1 S(0.96)S(0.04)PEQPIGQGR;S(0.853)S(0.147)PEQPIGQGR;S(0.5)S(0.5)PEQPIGQGR;S(0.947)S(0.053)PEQPIGQGR 130.44 0.00020925 126030000.0 77640.8 64325.4 77405.0 60821.5 60241.4 76912.0 70256.4 58109.2 73311.4 50595.6 True False 76533.62795442117 64176.458488440774 71041.0596919407 65294.51600457619 56698.119291149305 73622.65305062897 73893.9326247946 60809.165570064106 65054.29812873358 59340.98204560072 1.2897263462139659 1.0814862895110873 1.197166902922992 1.1003275266728896 0.9554631105966446 1.2406712951607957 1.245242833494239 1.0247414766970853 1.0962794326312706 1.0 15.856741182009602 -14.522747505974015 0.02149940259814998 1.3781061677336788e-06 1.8944550165847065 0.2080489292132348 0.09662536361306882 5365.361860078336 8.6945714787011 528.3081931689624 275.68161289747223 3.000906706002751e-15 14.522747505974015 1.8944536384785389 S(ph)SPEQPRPSTSK ddPTM_PC-9_AZD4547_30min_R2 1 SSPEQPRPSTSK 12 1 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BVD2;H3BT57;H3BUJ5;H3BRN3;P29590-2 P29590;P29590-2 PML Protein PML 1 S(0.5)S(0.5)PEQPRPSTSK 67.01899999999999 0.017872 174100000.0 215920.0 204920.0 284070.0 348930.0 309270.0 301750.0 203370.0 320090.0 261820.0 255830.0 True False 284578.06858499965 271156.382570991 280303.04619195906 268489.57941476046 266333.19888878806 282881.52479846205 221469.53602010594 270627.44543645903 275659.27068387606 246873.46956859165 1.1527284364832573 1.0983617763578786 1.1354117827313934 1.0875594687592096 1.0788247086825573 1.1458563177841428 0.8970973527739583 1.0962192329105964 1.1166014362158365 1.0 17.913412279008256 S(ph)SPEQPRPSTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPEQPRPSTSK 12 1 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BVD2;H3BT57;H3BUJ5;H3BRN3;P29590-2 P29590;P29590-2 PML Protein PML 1 S(0.995)S(0.005)PEQPRPSTSK;S(0.845)S(0.155)PEQPRPSTSK 146.67 0.0006082 231869000.0 87957.0 92822.0 94604.0 112392.0 109917.0 107585.0 104484.0 97549.0 91962.0 79518.0 True False 102846.38287006284 102036.75472077302 96859.71814766769 106095.04061978044 88379.5528957865 101943.05320743163 94586.51912134721 94988.44211170913 93306.7702749888 93933.98393585841 1.0948793882764531 1.086260269663932 1.0311467063273616 1.129463865731768 0.9408687803142185 1.0852627444934317 1.0069467423625338 1.0112255238377916 0.9933228248756286 1.0 16.519359577745597 -5.646080200541395 0.3919181441057546 0.9951237618691965 1.1291741442213115 0.339678482513042 0.04507292496929196 3.5037341730148452 0.6979538712993298 0.04024253046888382 0.2079692470328491 2.2590185619696886e-06 5.646080200541395 0.13405038235211497 S(ph)SPEQPRPSTSK ddPTM_PC-9_Lapatinib_30min_R1 5 SSPEQPRPSTSK 12 1 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BVD2;H3BT57;H3BUJ5;H3BRN3;P29590-2 P29590;P29590-2 PML Protein PML 1 S(0.727)S(0.273)PEQPRPSTSK;S(0.5)S(0.5)PEQPRPSTSK;S(0.5)S(0.5)PEQPRPSTSK;S(0.594)S(0.406)PEQPRPSTSK;S(0.5)S(0.5)PEQPRPSTSK 184.96 0.0021979 1033298400.0 317790.0 261062.9 289700.0 269561.7 299879.0 282093.0 257642.0 252588.0 283257.0 205495.8 True False 313258.2563244517 260458.42489470722 265881.9842743392 289386.1666494709 282240.7068047984 270028.5399809012 270981.4421080124 264324.16059782857 251353.6138315555 241015.47522405878 1.2997433298971064 1.0806709596243702 1.1031739104186709 1.200695376014526 1.1710480687699194 1.1203784310109985 1.1243321278689506 1.0967103268041232 1.0428940863564298 1.0 17.878766257042386 -8.09752068508738 0.722288453982806 0.9973741274361917 1.1652304156091642 0.509756249528168 0.0560159661729309 0.5653600464858138 0.6255948195722228 0.05323430051670686 0.022916606643106293 7.988758909625557e-09 8.09752068508738 0.1678562881729725 S(ph)SPGAGPSDHHSASR ddPTM_PC-9_AZD4547_30min_R2 4 SSPGAGPSDHHSASR 15 0 I3VM54;Q9Y2K7;Q9Y2K7-3;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 1 S(0.888)S(0.112)PGAGPSDHHSASR;S(0.866)S(0.134)PGAGPSDHHSASR;S(0.5)S(0.5)PGAGPSDHHSASR;S(0.5)S(0.5)PGAGPSDHHSASR 147.37 3.6911e-06 20949600.0 0.0 0.0 6532.7699999999995 16343.480000000001 7422.02 2390.67 540.92 11986.089999999998 526.26 3669.7599999999998 True False 0.0 0.0 6446.141201363911 12575.7431902489 6391.600636390744 2241.181026975768 589.0608320991099 10133.915203447426 554.0770292189167 3541.282819388011 0.0 0.0 1.8202842105895132 3.551182955904715 1.8048828524504328 0.6328726456711185 0.16634108658988972 2.861650910219796 0.15646223627930114 1.0 11.790056351727564 -6.754873687143766 24.99095232158617 1.0299982858983685 1.4944731314155633 0.035795145191628186 1.1799149108386655 745.9543923453446 2839318.6920476314 0.42982743162752224 0.4202252460695797 1.758434973545457e-07 6.754873687143766 0.46447484551719476 S(ph)SPGAGPSDHHSASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSPGAGPSDHHSASR 15 0 I3VM54;Q9Y2K7;Q9Y2K7-3;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 1 S(0.736)S(0.264)PGAGPSDHHSASR;S(0.5)S(0.5)PGAGPSDHHSASR;S(0.5)S(0.5)PGAGPSDHHSASR;S(0.5)S(0.5)PGAGPSDHHSASR 141.22 6.7699e-06 8773300.0 444.22 468.7 17229.4 5382.139999999999 14774.74 13235.9 4665.83 4598.1 7516.84 1531.27 True False 519.4176722550712 515.2294384696112 17640.214238863366 5080.596144933308 11879.735758358524 12541.786103529728 4223.848804716093 4477.404747089662 7626.759564535848 1808.8771294733488 0.28714922854174113 0.28483385083188006 9.752024585550087 2.8087016316097237 6.5674641824993865 6.93346490990311 2.335066730566635 2.4752398458336695 4.216294982266907 1.0 10.820878698856834 -5.099282695426428 24.351583285815043 4.614078550326399 0.2806900122036918 0.3152902726014656 2.4867983352201692 33.52594241000452 8214.485951949282 0.6220443620016756 1.6457771219491857 7.956412748264423e-06 5.099282695426428 -4.333388538122707 S(ph)SPGAGPSDHHSASR ddPTM_PC-9_Lapatinib_30min_R1 4 SSPGAGPSDHHSASR 15 0 I3VM54;Q9Y2K7;Q9Y2K7-3;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 1 S(0.894)S(0.106)PGAGPSDHHSASR;S(0.5)S(0.5)PGAGPSDHHSASR;S(0.5)S(0.5)PGAGPSDHHSASR;S(0.5)S(0.5)PGAGPSDHHSASR 185.71 2.3390999999999998e-07 5678630.0 478.73 0.0 8883.48 2843.26 2189.19 5957.95 1593.56 2166.05 11745.539999999999 2910.3900000000003 True False 471.90322241167 0.0 8153.114565624461 3052.3628252373132 2060.426148313138 5703.1423671597995 1676.0667394510367 2266.692590554291 10422.633599180548 3413.4470336490926 0.13824829205191716 0.0 2.3885282194956163 0.8942171345117467 0.6036203661582736 1.6707868354010882 0.4910188214226554 0.6640479750263236 3.0534042264128507 1.0 11.737013650460064 -5.214979443829114 24.95989245578484 1.2721632189727434 0.06912263320903449 0.2915303682576289 0.7893924576367054 535.8047341151565 287851.0893471974 0.19591343001667555 0.5183346770866432 6.095657487261507e-06 5.214979443829114 -1.203040585763709 S(ph)SPGAGPSDHHSASRDER ddPTM_PC-9_AZD4547_30min_R2 2 SSPGAGPSDHHSASRDER 18 1 I3VM54;Q9Y2K7;Q9Y2K7-3;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 1 S(0.5)S(0.5)PGAGPSDHHSASRDER;S(0.5)S(0.5)PGAGPSDHHSASRDER 69.256 0.0047108 2281240.0 0.0 549.13 4601.68 28184.5 8243.4 4600.6 1947.1 4373.0 743.39 4259.6 True False 0.0 726.625533677573 4540.6587165157025 21686.998971184246 7098.946201441578 4312.923754723457 2120.3881279674933 3697.253331543111 782.684077739236 4110.472700521332 0.0 0.17677420253524978 1.1046560936750194 5.276035276534906 1.7270388878975447 1.0492524993965897 0.5158501910737819 0.8994715695531047 0.19041218243341407 1.0 12.005088596691651 -6.912543639565196 3.8470707246182543 0.657317056003158 1.739313208313153 0.106011075864191 1.371084505515976 0.5813304969205996 16.60497264070086 0.5631058712312593 0.4885642639658858 1.2230842127105478e-07 6.912543639565196 1.081996152309995 S(ph)SPGAVAGLSNAPGTPR ddPTM_PC-9_AZD4547_30min_R2 1 SSPGAVAGLSNAPGTPR 17 0 U3KPY3;V9GYB2;Q9BWG4-2;Q9BWG4 U3KPY3 SSBP4 Single-stranded DNA-binding protein 4 1 S(0.5)S(0.5)PGAVAGLSNAPGTPR 82.94200000000001 0.0041294 16972000.0 19289.0 23277.0 27317.0 24167.0 27283.0 24663.0 18274.0 22986.0 26851.0 25663.0 True False 25422.50076387579 30800.83504345579 26954.758731389287 18595.671526427992 23495.22638886026 23120.81871119952 19900.350598571196 19434.041865732892 28270.28904259706 24764.546181209273 1.026568408637577 1.2437472028793608 1.0884414571603132 0.7508989419938544 0.9487444759511829 0.9336257786441097 0.8035822846481674 0.7847525944359507 1.141562976189237 1.0 14.595988562883262 -5.597864952371853 7.4923612360260945 0.8988667072972559 1.1427637115567124 0.3997905206596324 0.1185727818964437 0.19438943523803587 16.42527245727139 0.03109167931949344 0.054127812181459754 2.5242655926855464e-06 5.597864952371853 0.24389700425945648 S(ph)SPGAVAGLSNAPGTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSPGAVAGLSNAPGTPR 17 0 U3KPY3;V9GYB2;Q9BWG4-2;Q9BWG4 U3KPY3 SSBP4 Single-stranded DNA-binding protein 4 1 S(0.988)S(0.012)PGAVAGLSNAPGTPR;S(0.897)S(0.103)PGAVAGLSNAPGTPR;S(0.907)S(0.093)PGAVAGLSNAPGTPR 203.92 3.5653e-17 29951500.0 55356.0 52297.0 65315.0 63069.0 66381.0 62698.0 63609.0 49053.0 55756.0 54723.0 True False 64726.677469163325 57488.70054116765 66872.35730851692 59535.44840245682 53374.1195699956 59410.00650647908 57583.495030720296 47765.410725949645 56571.32602001116 64643.846712970335 1.0012813401492144 0.8893143503112871 1.0344736693260466 0.9209762634764657 0.8256643483328856 0.9190357555649435 0.8907807619555934 0.7389011198240752 0.8751231384975814 1.0 15.980225429566815 -6.00275473400431 24.575211024390814 0.8656306129960757 0.9683310412331629 0.2769908565036131 0.07140851006428521 111.47424637643455 994499.653053126 0.019776348866900606 0.028732562377470763 9.93677064964475e-07 6.00275473400431 0.10270042823708725 S(ph)SPGAVAGLSNAPGTPR ddPTM_PC-9_Lapatinib_30min_R1 3 SSPGAVAGLSNAPGTPR 17 0 U3KPY3;V9GYB2;Q9BWG4-2;Q9BWG4 U3KPY3 SSBP4 Single-stranded DNA-binding protein 4 1 S(0.494)S(0.494)PGAVAGLS(0.012)NAPGTPR;S(0.997)S(0.003)PGAVAGLSNAPGTPR;S(0.975)S(0.025)PGAVAGLSNAPGTPR 177.66 2.5302e-32 16559600.0 36237.9 46186.3 45889.0 39477.8 48954.2 49431.0 34785.0 44842.0 44376.0 31112.1 True False 35721.140900783044 46079.35846002785 42116.18355666257 42381.129106080225 46074.81020366027 47316.951359288985 36585.997095687824 46925.52302376929 39377.90758000366 36489.78503073259 0.9789353615182392 1.2628015873817475 1.1541910570640874 1.1614518712671449 1.2626769427349307 1.2967177340024745 1.0026366848934352 1.2859906679156223 1.0791487959394284 1.0 15.15520503126632 -8.518408562212649 22.372273343721126 0.9999999884199875 1.1788069251228344 0.22692268745534172 0.10553309011125268 103.44957491679331 517736.41791318724 0.09613549450954191 0.024822077950137272 3.031038395396459e-09 8.518408562212649 0.17880693670284686 S(ph)SPGGQDEGGFMAQGK ddPTM_PC-9_AZD4547_30min_R2 3 SSPGGQDEGGFMAQGK 16 0 A0A1B0GTU4;F5GZ78;P49023;A0A1B0GV30 A0A1B0GTU4 PXN Paxillin 1 S(0.5)S(0.5)PGGQDEGGFMAQGK;S(0.5)S(0.5)PGGQDEGGFMAQGK;S(0.806)S(0.194)PGGQDEGGFMAQGK 149.6 2.7000000000000002e-05 204034000.0 583581.0 616997.0 762051.0 833785.0 780690.0 741727.0 685118.0 877097.0 707344.0 729928.0 True False 769147.6187611279 816429.2142160533 751945.7058247228 641568.7500998363 672304.6691903139 695346.6934355889 746092.1747505681 741561.8123339738 744732.7597686041 704373.4428927934 1.09195999156685 1.159085741312247 1.0675384107847035 0.9108360864160006 0.9544719153936636 0.9871847106839624 1.0592281442162836 1.0527963821129476 1.0572981807917954 1.0 19.425980990464062 -5.525486629891029 24.891983782180347 1.0037500659328198 1.1224701848314496 0.5275306679998495 0.046874457303046006 60.64372555143657 578836.1539274963 0.014238584083219891 0.024849196405816506 2.982039351020107e-06 5.525486629891029 0.11872011889862977 S(ph)SPGGQDEGGFMAQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPGGQDEGGFMAQGK 16 0 A0A1B0GTU4;F5GZ78;P49023;A0A1B0GV30 A0A1B0GTU4 PXN Paxillin 1 S(0.827)S(0.173)PGGQDEGGFMAQGK;S(0.624)S(0.376)PGGQDEGGFMAQGK 214.54 1.2931999999999997e-64 59645000.0 100949.0 119182.0 122655.0 125952.0 117787.0 109802.0 120885.0 115497.0 95178.0 94270.0 True False 118037.67186636626 131013.60131360183 125579.5603716779 118895.31778189335 94707.4828910543 104043.78982462634 109433.89766838987 112465.32612918719 96569.79819091452 111360.40475909051 1.0599608731821772 1.1764828046110976 1.1276859189165858 1.0676624069309317 0.8504592192883816 0.9342978776855881 0.9827002506423327 1.0099220308375045 0.8671825358378233 1.0 16.764876834475956 -6.059004417349508 5.404016914234815 0.9432639469855268 1.1231623388322338 0.6925442491559826 0.055381506365772964 0.11784349056053653 7.201576992991884 0.01649780186834139 0.021909058123073522 8.729624891594e-07 6.059004417349508 0.17989839184670697 S(ph)SPGGQDEGGFMAQGK ddPTM_PC-9_Lapatinib_30min_R1 7 SSPGGQDEGGFMAQGK 16 0 A0A1B0GTU4;F5GZ78;P49023;A0A1B0GV30 A0A1B0GTU4 PXN Paxillin 1 S(0.5)S(0.5)PGGQDEGGFMAQGK;S(0.5)S(0.5)PGGQDEGGFMAQGK;S(0.5)S(0.5)PGGQDEGGFMAQGK;S(0.5)S(0.5)PGGQDEGGFMAQGK;S(0.5)S(0.5)PGGQDEGGFMAQGK;S(0.986)S(0.014)PGGQDEGGFMAQGK;S(0.971)S(0.029)PGGQDEGGFMAQGK 295.22 1.1859999999999997e-111 236171400.0 562877.0 715693.0 755720.0 646527.0 742103.0 720014.0 683210.0 710482.0 680354.0 533243.0 True False 554850.2707609994 714035.8568305456 693587.6187635593 694074.752330847 698453.9605706345 689220.6796546119 718583.2708277965 743493.5874620592 603725.368074766 625413.3420483641 0.8871737033043533 1.1417023092150922 1.1090067514260402 1.109785650011242 1.1167877523735688 1.1020242666989881 1.1489733629191228 1.1888035279627338 0.9653221757269116 1.0 19.25445047128482 -4.755900097957439 24.99993227108855 1.1069562144652068 0.8871733548850191 0.48759850890770884 0.06426877394969183 139.3249095617583 628736.2881113346 0.014923347578577365 0.12725780977399098 1.7542839985614853e-05 4.755900097957439 -0.21978285958018762 S(ph)SPGHAPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPGHAPAR 9 0 M0QXP1;Q10586 M0QXP1 DBP D site-binding protein 1 S(0.868)S(0.132)PGHAPAR 79.20100000000001 0.016212 0.0 3311.7 6015.7 7766.0 4979.2 10565.0 12119.0 6190.6 6061.5 9983.5 8616.0 True False 3872.3054009434954 6612.898939623726 7951.1708927190075 4700.231566784203 8494.86409148708 11483.458305719803 5604.181551937258 5902.39204769013 10129.489800573598 10178.012595781527 0.380457910078481 0.649723988587376 0.781210557355227 0.4618024906681983 0.834628962338673 1.128261357279057 0.5506164881599791 0.5799159700525907 0.9952325864454087 1.0 13.313168261383005 -4.328013975556639 0.5494595073808567 0.8180116364369229 2.212529230095241e-22 0.3032528913403124 0.19933851405821254 9.858663907020278 1.5747927897523233 0.11234988242319852 5.7356011436422065 4.698789876991463e-05 4.328013975556639 -0.8180116364369229 S(ph)SPGPAPR ddPTM_PC-9_AZD4547_30min_R2 2 SSPGPAPR 8 0 Q9H330-4;Q9H330 Q9H330-4 TMEM245 Transmembrane protein 245 1 S(0.987)S(0.013)PGPAPR;S(0.985)S(0.015)PGPAPR 99.13600000000001 0.0052923 122465000.0 147697.0 109719.0 178795.0 189345.0 146955.0 132892.0 166511.0 193690.0 156220.0 146155.0 True False 194661.57371155353 145183.52107801364 176424.0614774225 145694.43560108863 126552.83487794471 124582.24223203724 181330.15642545043 163759.66105341507 164477.47027054915 141038.15793611953 1.3802050208265033 1.0293917844826905 1.2508959565207192 1.033014311397048 0.8972950067545857 0.8833229535546283 1.285681542349556 1.1611018142167369 1.1661912823978173 1.0 17.1057260116538 S(ph)SPGPAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPGPAPR 8 0 Q9H330-4;Q9H330 Q9H330-4 TMEM245 Transmembrane protein 245 1 S(0.982)S(0.018)PGPAPR;S(0.964)S(0.036)PGPAPR 88.177 0.011170999999999999 101880900.0 126473.6 159961.9 139090.8 157645.5 203965.7 151215.7 141074.0 133225.2 119923.4 117929.9 True False 147883.08251253635 175841.860280632 142407.25217679638 148813.13372860712 164000.08526502867 143285.68249197412 127710.44943268804 129728.17966376778 121677.05285221669 139309.65733742513 1.0615422170937174 1.2622374043654518 1.0222353202109205 1.0682183602545472 1.1772341444197245 1.0285409154723464 0.9167379482052533 0.9312217267863215 0.8734286996162792 1.0 17.08793574752226 -7.050091766426943 3.4999127391047518 0.9256378217837148 1.1180516401289182 0.6182453897947395 0.0693435812849206 0.15885486885780536 3.9187594480557357 0.027194303257021143 0.021436650536942707 8.91062636699279e-08 7.050091766426943 0.19241381834520344 S(ph)SPGPAPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPGPAPR 8 0 Q9H330-4;Q9H330 Q9H330-4 TMEM245 Transmembrane protein 245 1 S(0.984)S(0.016)PGPAPR 86.13600000000001 0.012702 51440000.0 68199.0 70459.0 68721.0 46037.0 60757.0 54617.0 54204.0 58046.0 68960.0 43663.0 True False 67226.46975383526 70295.85651448798 63071.02465073123 49422.71455493001 57183.392712857894 52281.15822844548 57010.41789779107 60743.029067341195 61192.99861900697 51210.09137270961 1.3127582465057062 1.3726953932355093 1.2316132027903866 0.9650971757739899 1.116643051789818 1.0209151522097586 1.1132653031775785 1.1861534990291345 1.1949402349947251 1.0 15.644140512798284 -5.540258831528231 6.248265105018476 1.0925894861622696 1.3341725951887409 0.6772401063106728 0.07227971910662315 0.08985866065383477 13.30538390230529 0.020390818191952795 0.037084217783010694 2.8823131854572985e-06 5.540258831528231 0.2415831090264713 S(ph)SPGPDTLVVLEFNPASK ddPTM_PC-9_AZD4547_30min_R2 3 SSPGPDTLVVLEFNPASK 18 0 O60303 O60303 KIAA0556 Uncharacterized protein KIAA0556 1 S(0.5)S(0.5)PGPDTLVVLEFNPASK;S(0.491)S(0.491)PGPDT(0.017)LVVLEFNPASK;S(0.5)S(0.5)PGPDTLVVLEFNPASK 303.44 1.0203999999999996e-137 58327300.0 120213.0 168585.0 170724.0 134257.0 167101.0 184291.0 168272.0 204441.0 157196.0 142031.0 True False 158438.2334142669 223076.80439064276 168460.08821092022 103306.12289997288 143901.91052321706 172767.25463672998 183247.88201394165 172849.34103681802 165505.05963800562 137058.53792087184 1.155989519644068 1.6276023936533743 1.229110501004888 0.7537372313107171 1.0499302904157355 1.2605362442759596 1.3370045003671085 1.261135159172713 1.2075501617677904 1.0 17.064432676605875 -2.5678539261140454 0.016715220251293728 1.141251759257882e-05 2.6094863723236688 0.058452169693953504 0.21084409320959566 15322.516368464885 23.701467030392894 1501.3316195787004 2269.5417353531802 0.002704867986852181 2.5678539261140454 2.609474959806076 S(ph)SPGPDTLVVLEFNPASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSPGPDTLVVLEFNPASK 18 0 O60303 O60303 KIAA0556 Uncharacterized protein KIAA0556 1 S(0.5)S(0.5)PGPDTLVVLEFNPASK;S(0.5)S(0.5)PGPDTLVVLEFNPASK;S(0.5)S(0.5)PGPDTLVVLEFNPASK 219.85 7.4661e-28 40025000.0 74447.0 100865.0 91943.0 83753.0 101821.0 76025.0 81860.0 53758.2 59164.0 60674.0 True False 87049.40670472577 110878.2106064378 94135.26981576932 79060.59094088979 81869.90597816416 72038.11516563637 74105.62818492297 52347.104211521146 60029.16157270862 71673.71590488029 1.2145234219508152 1.5469856586420974 1.3133862061888664 1.103062537539044 1.1422584268801614 1.0050841407642332 1.0339303222853706 0.7303528713509441 0.83753382693838 1.0 16.129156532147356 -6.3692844514374825 0.7555852367149043 0.8590779710402281 1.4075084981251025 0.7176712618270187 0.11745167881794856 0.3598159853162267 0.45129757926446995 0.07127767587790176 0.10953993616418148 4.272829354220559e-07 6.3692844514374825 0.5484305270848744 S(ph)SPGPDTLVVLEFNPASK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPGPDTLVVLEFNPASK 18 0 O60303 O60303 KIAA0556 Uncharacterized protein KIAA0556 1 S(0.5)S(0.5)PGPDTLVVLEFNPASK 174.35 2.5996999999999998e-08 21510000.0 76904.0 87277.0 78965.0 92155.0 118590.0 111880.0 101300.0 96724.0 93000.0 83345.0 True False 75807.33485753348 87074.91546878283 72472.80251371472 98932.38612006794 111614.76935691063 107095.15320501816 106544.81833529338 101218.15014832224 82525.36066658428 97751.07219976818 0.7755141007825515 0.8907822032972987 0.7414016121031007 1.0120849203360713 1.14182654824297 1.095590573023629 1.089960610534828 1.0354684390721423 0.8442399536849273 1.0 16.576824906509643 -5.841323065121044 6.23909768775788 1.0445475281665781 0.8121693536738577 0.6112100357589527 0.08325550398462013 0.13774379585483518 8.44815368115497 0.024294178336623506 0.03656531943845144 1.4410429825539889e-06 5.841323065121044 -0.23237817449272047 S(ph)SPGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPR ddPTM_PC-9_AZD4547_30min_R2 2 SSPGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPR 36 1 P40222 P40222 TXLNA Alpha-taxilin 1 S(0.5)S(0.5)PGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPR;S(0.5)S(0.5)PGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPR 113.9 2.1772999999999998e-24 179394000.0 10709.099999999999 7071.0 20554.6 26011.8 19854.2 15145.3 19211.4 26230.2 10593.099999999999 15352.2 True False 14114.371036882281 9356.562469058546 20282.03257386293 20015.181388303867 17097.7870384382 14198.261996785875 20921.17738258677 22176.9253000325 11153.029639757733 14814.724150846001 0.9527258754984158 0.6315718317660498 1.369045577045369 1.3510330117865132 1.1541076880234604 0.9583885499464448 1.4121881156587082 1.4969516188234986 0.7528341078912923 1.0 13.854744143215399 -5.2614964899639185 24.9999999773415 1.2091541088318567 0.7921488438717911 0.31262252880602737 0.23220723838086094 5.35178082689246 2344016.581204426 0.05910371663637183 0.13720482596298483 5.47650527141416e-06 5.2614964899639185 -0.4170052649600656 S(ph)SPGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPR 36 1 P40222 P40222 TXLNA Alpha-taxilin 1 S(0.499)S(0.499)PGQPEAGPEGAQERPS(0.001)QAAPAVEAEGPGSSQAPR;S(0.5)S(0.5)PGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPR 83.695 2.9286e-10 78325200.0 11612.9 4783.4 7451.5 8136.7 13401.7 7890.8 8368.0 7484.799999999999 11829.7 4521.9 True False 13578.734604769974 5258.264339610706 7629.17201997112 7680.827078537322 10775.73308990842 7476.992557040494 7575.322460926406 7288.33193080113 12002.68698290635 5341.684674659295 2.5420322298668925 0.9843831412504878 1.4282333167593286 1.4379034979310574 2.0172911255933923 1.3997442777764477 1.4181523100499336 1.3644257148641963 2.246985307808704 1.0 12.383079099322456 -11.364654240611442 2.9096205084814217 0.7904331974196781 1.6049290041546374 0.1505726564935872 0.4516044141369761 91852045.51346062 102056792.55017775 136660236.31853914 0.10999521262884465 4.318627633974085e-12 11.364654240611442 0.8144958067349592 S(ph)SPGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPR ddPTM_PC-9_Lapatinib_30min_R1 2 SSPGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPR 36 1 P40222 P40222 TXLNA Alpha-taxilin 1 S(0.5)S(0.5)PGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPR;S(0.499)S(0.499)PGQPEAGPEGAQERPS(0.001)QAAPAVEAEGPGSSQAPR 74.025 1.2139e-08 133407000.0 15240.9 17031.3 16742.7 21506.1 24540.5 16284.2 20726.0 17552.7 23042.2 16460.0 True False 15023.561971161253 16991.865071249948 15366.179834690984 23087.73033624649 23097.076038479343 15587.76272632426 21799.090866903134 18368.26252128174 20446.94479087707 19305.08906842864 0.778217697826147 0.8801754299615372 0.7959652390219059 1.1959401095954512 1.1964242152216786 0.8074431913301213 1.129188826305555 0.9514725602235643 1.0591479126773786 1.0 14.23669359004698 -5.740020393379786 24.997743066609406 1.0459741498633728 0.824324934367914 0.46863366073539536 0.11234497236658068 223.61827785681663 260979.14588945513 0.03074096802169047 0.05318244840211265 1.8196154120271378e-06 5.740020393379786 -0.2216492154954588 S(ph)SPGQTPEEGAQALAEFAALHGPALR ddPTM_PC-9_AZD4547_30min_R2 8 SSPGQTPEEGAQALAEFAALHGPALR 26 0 Q14166 Q14166 TTLL12 Tubulin--tyrosine ligase-like protein 12 1 S(0.413)S(0.413)PGQT(0.175)PEEGAQALAEFAALHGPALR;S(0.487)S(0.487)PGQT(0.027)PEEGAQALAEFAALHGPALR;S(0.488)S(0.488)PGQT(0.025)PEEGAQALAEFAALHGPALR;S(0.499)S(0.499)PGQT(0.002)PEEGAQALAEFAALHGPALR;S(0.487)S(0.487)PGQT(0.026)PEEGAQALAEFAALHGPALR;S(0.484)S(0.484)PGQT(0.032)PEEGAQALAEFAALHGPALR;S(0.499)S(0.499)PGQT(0.003)PEEGAQALAEFAALHGPALR;S(0.485)S(0.485)PGQT(0.03)PEEGAQALAEFAALHGPALR 224.91 2.8338999999999996e-54 2455319000.0 474495.4 488157.3 697917.8999999999 894157.6 769583.3999999999 660157.2999999999 534779.2 741270.2000000001 523043.5 722545.7000000001 True False 625375.0670825618 645944.6007887071 688663.0526345442 688023.3799172094 662740.0288864418 618877.5596713686 582373.5127954158 626723.9232846161 550690.5115955315 697249.5949687937 0.8969170747392851 0.9264180365965179 0.9876851239553122 0.986767701095621 0.9505061511238363 0.8875983064559073 0.835243959978895 0.8988516132629176 0.7898039892302531 1.0 19.411315665631335 -6.81012565075629 4.323176690609079 0.8713960998368594 0.9529245156952361 0.25753088049583495 0.05611684069619198 0.2524773165553686 9.90052478174724 0.019437030256306092 0.017537478108951683 1.5483685776918062e-07 6.81012565075629 0.08152841585837667 S(ph)SPGQTPEEGAQALAEFAALHGPALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 SSPGQTPEEGAQALAEFAALHGPALR 26 0 Q14166 Q14166 TTLL12 Tubulin--tyrosine ligase-like protein 12 1 S(0.468)S(0.468)PGQT(0.065)PEEGAQALAEFAALHGPALR;S(0.484)S(0.484)PGQT(0.032)PEEGAQALAEFAALHGPALR;S(0.45)S(0.45)PGQT(0.1)PEEGAQALAEFAALHGPALR;S(0.43)S(0.43)PGQT(0.14)PEEGAQALAEFAALHGPALR;S(0.408)S(0.408)PGQT(0.184)PEEGAQALAEFAALHGPALR;S(0.453)S(0.453)PGQT(0.093)PEEGAQALAEFAALHGPALR;S(0.429)S(0.429)PGQT(0.141)PEEGAQALAEFAALHGPALR 153.34 3.8392e-12 961658900.0 55222.2 60008.5 63865.7 77699.2 88189.5 73000.7 77122.40000000001 72546.4 68952.5 57329.1 True False 64570.22777183372 65965.74729763961 65388.500500015994 73345.96572820502 70909.40054862281 69172.41478161231 69816.80795417674 70642.13386926448 69960.7998671861 67722.41201309401 0.9534543418115288 0.9740608070026396 0.9655370881854184 1.0830382963032046 1.0470595839810402 1.0214109734933532 1.0309261864547556 1.043113081317983 1.0330523941418286 1.0 16.0473457369732 -5.736337264800933 24.908047960738596 1.038262968731866 0.9653216803736984 0.7268988148410045 0.02037648411621935 110.62227937283235 109766.156825813 0.005486843382977398 0.009498553360086651 1.8351126763877552e-06 5.736337264800933 -0.07294128835816771 S(ph)SPGQTPEEGAQALAEFAALHGPALR ddPTM_PC-9_Lapatinib_30min_R1 8 SSPGQTPEEGAQALAEFAALHGPALR 26 0 Q14166 Q14166 TTLL12 Tubulin--tyrosine ligase-like protein 12 1 S(0.429)S(0.429)PGQT(0.142)PEEGAQALAEFAALHGPALR;S(0.48)S(0.48)PGQT(0.04)PEEGAQALAEFAALHGPALR;S(0.481)S(0.481)PGQT(0.038)PEEGAQALAEFAALHGPALR;S(0.43)S(0.43)PGQT(0.14)PEEGAQALAEFAALHGPALR;S(0.482)S(0.482)PGQT(0.036)PEEGAQALAEFAALHGPALR;S(0.478)S(0.478)PGQT(0.044)PEEGAQALAEFAALHGPALR;S(0.447)S(0.447)PGQT(0.107)PEEGAQALAEFAALHGPALR;S(0.441)S(0.441)PGQT(0.118)PEEGAQALAEFAALHGPALR 164.06 3.1440999999999997e-13 1753109970.0 448878.21 414648.74 445793.54000000004 345467.32 388521.3 405050.65 369101.19 337610.82 409432.27 279800.6 True False 442477.124411218 413688.64631847315 409142.1159540286 370874.13915799616 365669.24099626526 387727.5779186824 388211.44359220716 353297.4512060938 363317.6962396594 328163.7608991358 1.3483424348833493 1.2606164836269786 1.2467620276931866 1.1301495879430385 1.1142889147612407 1.1815063822292498 1.1829808462962113 1.0765888659920713 1.107123148650556 1.0 18.324056405373312 -1.5228787452803376 0.19287799912921968 1.0253490500130376 2.4287047265827164 0.8173481294493325 0.041040500410181986 24.725449960141134 0.2918625989071417 0.08805925418030251 10.372595893161904 0.029999999999999995 1.5228787452803376 1.4033556765696789 S(ph)SPGSVAASPSGGGGR ddPTM_PC-9_AZD4547_30min_R2 2 SSPGSVAASPSGGGGR 16 0 Q9BXB5-2;Q9BXB5 Q9BXB5-2 OSBPL10 Oxysterol-binding protein-related protein 10 1 S(0.84)S(0.159)PGSVAASPSGGGGR;S(0.999)S(0.001)PGSVAASPSGGGGR 217.01 4.241399999999999e-22 9853500.0 14519.5 12996.599999999999 14026.8 26125.0 19756.2 19368.6 15763.4 19493.9 15458.2 16548.8 True False 19136.39897563868 17197.496787634882 13840.795467051697 20102.284877226437 17013.39264683507 18157.478380154036 17166.312062247856 16481.565680258 16275.288893459236 15969.431549062698 1.198314349314573 1.0769009989365754 0.8667055821322621 1.2587977734502585 1.06537246454672 1.137014697384126 1.0749482227659761 1.0320696531759368 1.019152675751598 1.0 13.963025338764199 -7.780587547268128 2.682245204847326 1.0131710742658044 1.0951406724987527 0.130818137846216 0.09637500331307072 0.6569875935703161 9.473627898971994 0.0618804233556127 0.027234765981707883 1.6573432075845624e-08 7.780587547268128 0.08196959823294825 S(ph)SPGSVAASPSGGGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSPGSVAASPSGGGGR 16 0 Q9BXB5-2;Q9BXB5 Q9BXB5-2 OSBPL10 Oxysterol-binding protein-related protein 10 1 S(0.843)S(0.157)PGSVAASPSGGGGR;S(0.996)S(0.004)PGSVAASPSGGGGR;S(0.996)S(0.004)PGSVAASPSGGGGR 132.65 5.8466e-06 10388700.0 21004.3 20825.5 24252.899999999998 21258.100000000002 28700.8 24450.600000000002 21919.3 21991.199999999997 23017.6 18500.9 True False 24559.913136164934 22892.918009065274 24831.181115635452 20067.07757669009 23077.08427041669 23168.3674931787 19842.945222010527 21413.954301602436 23354.188854979016 21854.966716956198 1.1237680411158029 1.0474926960791837 1.136180230206901 0.9181930055798726 1.0559194424447378 1.0600962148893824 0.9079375630718923 0.9798209523233178 1.0685986923448227 1.0 14.415673560586836 -5.745701984740974 24.99998601028866 0.9989779789763756 1.096981564665949 0.41555517821175936 0.056312205270752286 253.93516078771606 403391.14861433086 0.015332349273971944 0.026443614700624948 1.7959656055525252e-06 5.745701984740974 0.09800358568957346 S(ph)SPGSVAASPSGGGGR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPGSVAASPSGGGGR 16 0 Q9BXB5-2;Q9BXB5 Q9BXB5-2 OSBPL10 Oxysterol-binding protein-related protein 10 1 S(0.986)S(0.014)PGSVAASPSGGGGR 94.339 0.0026135000000000004 4574400.0 8121.4 9347.0 9792.5 6775.9 10242.0 8498.5 8137.4 8337.1 7563.2 5979.3 True False 8005.587346717646 9325.357595777967 8987.398450143133 7274.222289739779 9639.585696546743 8135.038965971099 8558.714755396002 8724.47210207991 6711.352771973218 7012.814038083562 1.1415656116421684 1.3297597148785039 1.2815680554676705 1.0372757997341184 1.374567419611916 1.1600249089442867 1.2204394282975881 1.2440757810917376 0.9570127962222814 1.0 12.77577775659264 -8.26099898255488 24.9999935472259 0.9785063694397883 1.2257155204186763 0.5327836840185085 0.09181311005009296 28.116221480352984 1596338.0380165707 0.06825477861846663 0.022186822515940566 5.4827824940039145e-09 8.26099898255488 0.24720915097888796 S(ph)SPHGSLGSVVNSLSGLK ddPTM_PC-9_AZD4547_30min_R2 1 SSPHGSLGSVVNSLSGLK 18 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5;X6R5W5;A0A0A0MRX3 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 S(0.474)S(0.474)PHGS(0.052)LGS(0.001)VVNSLSGLK 67.727 0.0071911 2945900.0 7701.2 5776.1 27689.0 40846.0 27976.0 32264.0 14423.0 39973.0 25832.0 31296.0 True False 10150.021405088928 7643.111367208183 27321.825768328796 31429.58576440921 24092.01530091098 30246.526979610815 15706.61905894672 33796.091338159786 27197.426782926774 30200.336565761016 0.3360896784374349 0.25308033738516 0.9046861351639481 1.0407031622303782 0.7977399605613928 1.0015294668570736 0.5200809277322347 1.1190634006534677 0.9005670093677457 1.0 14.882277007213998 -5.263816300143621 24.91784909710797 0.9047224126173585 0.29458496621451347 0.7117500620335855 0.15676068458354916 92.90046667526362 973911.05194843 0.039470282083288295 0.0889158352099065 5.447330177694561e-06 5.263816300143621 -0.6101374464028451 S(ph)SPHGSLGSVVNSLSGLK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPHGSLGSVVNSLSGLK 18 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5;X6R5W5;A0A0A0MRX3 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 S(0.4)S(0.4)PHGS(0.196)LGS(0.004)VVNSLSGLK 61.821000000000005 0.012709 2524300.0 12358.0 10792.0 20932.0 15133.0 20042.0 19702.0 14824.0 15525.0 25087.0 11878.0 True False 12181.772653820348 10767.011787058509 19211.051759856644 16245.931302208124 18863.168964088054 18859.39138760519 15591.514185610935 16246.348176798945 22261.437882178467 13931.096473559865 0.8744302845752596 0.772876119801012 1.3790050048334475 1.1661631468163067 1.3540333311084938 1.353762169646793 1.1191878697561541 1.1661930708493224 1.5979673907526906 1.0 13.766021192026543 -5.2569005657140515 24.962452097366327 1.2702955581561917 0.8236531567762486 0.551340349259826 0.15996750817889555 254.84634655166022 1401584.5650127493 0.0391380111457836 0.09659018278630561 5.534768164951655e-06 5.2569005657140515 -0.44664240137994304 S(ph)SPKEELHPAAPSQLAPSFSSSSSSSSGPR ddPTM_PC-9_AZD4547_30min_R2 3 SSPKEELHPAAPSQLAPSFSSSSSSSSGPR 30 1 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 S(0.499)S(0.499)PKEELHPAAPS(0.001)QLAPSFSSSSSSSSGPR;S(0.5)S(0.5)PKEELHPAAPSQLAPSFSSSSSSSSGPR;S(0.5)S(0.5)PKEELHPAAPS(0.001)QLAPSFSSSSSSSSGPR 73.60300000000001 4.352e-06 89695000.0 44040.1 40255.1 56156.8 83683.0 78554.9 66550.0 49190.5 66663.9 64197.6 79601.0 True False 58043.93570901376 53266.77384361459 55412.12413979871 64391.17723946177 67648.90809127594 62388.617979577844 53568.359205374676 56362.526039025135 67590.95407400202 76814.19321865891 0.7556407647709866 0.6934496297056151 0.7213787168481067 0.8382718680148883 0.880682400695232 0.8122016956161046 0.6973757968515955 0.7337514550023827 0.8799279305270828 1.0 16.229085286775856 -14.522878745280336 0.20934003776548873 2.0712360535773637 0.7450658303402694 0.5409840292764746 0.06388655130814883 129.9475181694284 1.2912794802612408 58.35389856331543 0.15422413663598905 3.0000000000000132e-15 14.522878745280336 -1.3261702232370944 S(ph)SPKEELHPAAPSQLAPSFSSSSSSSSGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPKEELHPAAPSQLAPSFSSSSSSSSGPR 30 1 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 S(0.5)S(0.5)PKEELHPAAPSQLAPSFSSSSSSSSGPR 110.44 1.0777000000000001e-15 16571000.0 6694.0 9982.0 6568.0 10812.0 15188.0 13704.0 10495.0 11226.0 11293.0 8344.0 True False 7827.161987473432 10972.946991260214 6724.606029278711 10206.238692976942 12212.02042797026 12985.338115486773 9500.837622779945 10931.329394930191 11458.138760742997 9856.701148932343 0.7940954959683701 1.1132474065573938 0.6822369804736451 1.0354619196385455 1.2389561419636872 1.3174121766787377 0.963896285301199 1.109025142363604 1.1624719657838178 1.0 13.266889169358564 -5.993134727892045 24.852924970166615 1.1381835019609947 0.88330710851711 0.4238838940624352 0.13944509500043345 157.32395698644575 569519.0013950501 0.03869845617633081 0.05724687328139691 1.0159334786215754e-06 5.993134727892045 -0.2548763934438847 S(ph)SPKEELHPAAPSQLAPSFSSSSSSSSGPR ddPTM_PC-9_Lapatinib_30min_R1 4 SSPKEELHPAAPSQLAPSFSSSSSSSSGPR 30 1 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 S(0.5)S(0.5)PKEELHPAAPS(0.001)QLAPSFSSSSSSSSGPR;S(0.5)S(0.5)PKEELHPAAPSQLAPSFSSSSSSSSGPR;S(0.499)S(0.499)PKEELHPAAPS(0.001)QLAPSFSSSSSSSSGPR;S(0.5)S(0.5)PKEELHPAAPSQLAPSFSSSSSSSSGPR 84.398 6.3873e-09 92832000.0 44818.799999999996 44585.6 48336.3 44463.1 59648.8 57134.4 43765.700000000004 56167.3 62442.0 45474.2 True False 44179.675693238685 44482.364782531105 44362.275997513774 47733.0646985535 56140.37485805286 54690.89489879146 46031.67379878527 58777.03780680963 55409.12441658977 53334.35487943728 0.8283530529825885 0.8340283647019606 0.8317767431104218 0.8949778207021434 1.0526118668718993 1.0254346381880994 0.8630773523527232 1.1020483502552076 1.038901183708747 1.0 15.702777511929243 -6.065137759651685 3.6247325746086405 1.0114166769190107 0.8337235907188466 0.6741537043154895 0.05778247635704109 0.14845008785308583 3.826440327521607 0.018082147270257243 0.02495238772092191 8.607206854187089e-07 6.065137759651685 -0.1776930862001641 S(ph)SPKSEIEVISEPPEEK ddPTM_PC-9_AZD4547_30min_R2 2 SSPKSEIEVISEPPEEK 17 1 B7ZM87;O75044;A0A075B7E9;A0A075B7E6;Q5VZB4 B7ZM87 SRGAP2 SLIT-ROBO Rho GTPase-activating protein 2 1 S(0.499)S(0.499)PKS(0.002)EIEVISEPPEEK;S(0.836)S(0.163)PKS(0.001)EIEVISEPPEEK 161.04 1.4209e-05 10528300.0 70261.0 69235.0 69645.0 68823.0 84086.0 73754.0 68598.0 65866.0 61529.0 76307.0 True False 92602.53648041263 91613.8597857826 68721.46179476533 52956.92065475038 72412.11033001138 69142.15072074824 74703.08910806556 55687.92315010718 64781.29732605693 73635.51515604308 1.257579800781946 1.2441531724418726 0.9332651730504737 0.7191763450357872 0.9833856689473938 0.9389782983690298 1.014498084922203 0.7562644605948277 0.879756150123715 1.0 16.168114140143153 -5.277933416386229 4.782788809754757 0.8941140318814019 1.2563306322760213 0.6933678190145687 0.09264239179412663 0.09494392645766352 6.199550074041847 0.024657372169596948 0.05902190989082283 5.273106995686059e-06 5.277933416386229 0.36221660039461934 S(ph)SPKSEIEVISEPPEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSPKSEIEVISEPPEEK 17 1 B7ZM87;O75044;A0A075B7E9;A0A075B7E6;Q5VZB4 B7ZM87 SRGAP2 SLIT-ROBO Rho GTPase-activating protein 2 1 S(0.499)S(0.499)PKS(0.002)EIEVISEPPEEK;S(0.497)S(0.497)PKS(0.005)EIEVISEPPEEK;S(0.475)S(0.475)PKS(0.05)EIEVISEPPEEK;S(0.49)S(0.49)PKS(0.02)EIEVISEPPEEK 132.14 1.1622e-05 19239400.0 187682.0 113753.0 127454.0 212462.0 219278.0 196176.0 216868.0 216509.0 186933.0 174552.0 True False 219452.85571153063 125045.64607261324 130492.98673198643 200558.44295109788 176312.0500002941 185888.1852118896 196324.69305164772 210825.86816024737 189666.54148250906 206196.89584712795 1.0642878730542602 0.6064380627985819 0.6328562134549904 0.9726550059210864 0.8550664609956586 0.9015081650390363 0.9521224470672954 1.0224492822459912 0.9198321861407928 1.0 17.653663088521768 -6.35800886614958 1.184214168771458 0.9672630257384384 0.7710121037308475 0.22746261979134974 0.1301928313310314 0.6521019742572286 1.8952736002876052 0.05639249395706699 0.07511355445919726 4.3852174523417143e-07 6.35800886614958 -0.19625092200759087 S(ph)SPKSEIEVISEPPEEK ddPTM_PC-9_Lapatinib_30min_R1 4 SSPKSEIEVISEPPEEK 17 1 B7ZM87;O75044;A0A075B7E9;A0A075B7E6;Q5VZB4 B7ZM87 SRGAP2 SLIT-ROBO Rho GTPase-activating protein 2 1 S(0.496)S(0.496)PKS(0.008)EIEVISEPPEEK;S(0.499)S(0.499)PKS(0.001)EIEVISEPPEEK;S(0.495)S(0.495)PKS(0.01)EIEVISEPPEEK;S(0.499)S(0.499)PKS(0.002)EIEVISEPPEEK 136.96 1.4492000000000001e-05 21883500.0 227413.0 207609.0 214003.0 228569.0 212060.0 219730.0 195112.0 190692.0 216752.0 188746.0 True False 224170.04891756354 207128.29411595906 196408.49941546924 245378.72674383246 199587.0477260012 210332.66011564768 205213.9446696517 199552.2464753717 192339.10726025235 221370.49461176392 1.0126464654230882 0.9356635105288869 0.8872388335217273 1.108452719384188 0.9015973338092497 0.950138637421061 0.9270157932725076 0.9014401256379866 0.868856112001618 1.0 17.756103419618817 S(ph)SPLKITLFLEEDK ddPTM_PC-9_AZD4547_30min_R2 2 SSPLKITLFLEEDK 14 1 Q9NQW6 Q9NQW6 ANLN Actin-binding protein anillin 1 S(0.5)S(0.5)PLKITLFLEEDK;S(0.77)S(0.23)PLKITLFLEEDK 131.08 8.2408e-06 7268500.0 26710.0 15102.199999999999 24642.4 35924.0 35496.0 24795.8 20459.1 22633.2 20731.3 28240.0 True False 35203.22439748678 19983.69081038269 24315.625674941875 27642.276820267274 30567.99310555964 23245.314706206107 22279.92026547161 19135.75899919541 21827.114194212227 27251.326195587015 1.291798576877608 0.7333107631884271 0.8922731136248138 1.014346113722112 1.121706623970092 0.8529975583342573 0.8175719634914335 0.702195513783626 0.800956035590915 1.0 14.734038820420308 -6.950772238206048 10.024086440458428 0.8095974053112642 0.9889678903604884 0.24073113405569935 0.15251542704883142 0.6208743875145761 122.04209758834871 0.053351368338439835 0.04702328438291126 1.1200251164621764e-07 6.950772238206048 0.17937048504922415 S(ph)SPLKITLFLEEDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPLKITLFLEEDK 14 1 Q9NQW6 Q9NQW6 ANLN Actin-binding protein anillin 1 S(0.497)S(0.497)PLKIT(0.006)LFLEEDK 53.188 0.0403 2983400.0 6478.5 1016.4 3288.5 6734.5 6085.1 9307.8 8490.7 9332.9 8759.8 5046.0 True False 7575.182093792437 1117.3014748464116 3366.9103117057 6357.187798543586 4892.768337255851 8819.682582554567 7686.399428655335 9087.921264024948 8887.895503086553 5960.799855885975 1.2708331561094681 0.18744153500526198 0.5648420334698965 1.0664991196217062 0.8208241268870151 1.4796139437303193 1.2894912787694794 1.5246143946690485 1.4910575288499621 1.0 12.541290217815098 -6.469488013618241 1.4185346699752275 1.393516434090817 0.6644771363325986 0.43925557037172547 0.31248239201987166 0.3403793554376256 1.3997035583386341 0.12405545598795069 0.1441946272421537 3.3924385242856305e-07 6.469488013618241 -0.7290392977582184 S(ph)SPLKITLFLEEDK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPLKITLFLEEDK 14 1 Q9NQW6 Q9NQW6 ANLN Actin-binding protein anillin 1 S(0.5)S(0.5)PLKITLFLEEDK 76.71300000000001 0.0075399 2166700.0 25911.0 10453.0 13395.0 13120.0 9069.5 9482.8 7033.4 6964.7 12658.0 8886.6 True False 25541.504388504563 10428.79672073041 12293.714806195274 14084.888567036975 8536.049841323053 9077.242749486468 7397.555037309495 7288.305387887388 11232.322745350784 10422.636969349818 2.4505798737512667 1.0005909974029323 1.1795205802857562 1.3513747632635442 0.8189913806290373 0.8709161391862928 0.7097584861742495 0.6992765275544318 1.077685309234317 1.0 13.34743271103404 -2.8896153850468353 1.2962647980017976 0.9233211762738714 199.9999977398228 0.8202808538675287 0.20576054243565486 82.22120420424179 1.3785348719074733 0.06395024699143423 47509.793525644294 0.0012893909419873545 2.8896153850468353 199.07667656354892 up S(ph)SPLLR ddPTM_PC-9_AZD4547_30min_R2 1 SSPLLR 6 0 P56524-2;P56524;Q9UQL6-2;Q9UQL6;Q9UQL6-3;Q9UKV0-10;Q9UKV0-3;Q9UKV0-4;Q9UKV0-2;Q9UKV0;Q9UKV0-5;Q9UKV0-7 P56524-2;Q9UKV0-10 HDAC4;HDAC5;HDAC9 Histone deacetylase 4;Histone deacetylase 5;Histone deacetylase 9 1 S(0.671)S(0.329)PLLR 92.47 0.035436 3430100.0 9868.3 8483.8 19454.0 26189.0 19210.0 20402.0 17226.0 21464.0 16312.0 17282.0 True False 13006.21412660871 11226.022440248744 19196.027248982205 20151.530666016562 16543.02308873677 19126.25971479109 18759.08062881621 18147.23199365227 17174.21901839198 16676.962440231397 0.7798910726831525 0.6731455131881307 1.151050577572438 1.2083453889302491 0.9919686002786986 1.1468671098431584 1.1248499656965063 1.0881617116240547 1.0298169753600335 1.0 14.025568918242923 -5.261600415234292 24.999998297598253 1.0994062115128649 0.7265182671469744 0.81213377825375 0.07037447847857115 5.087484675752798 789968.2490237348 0.01787428013636934 0.0414183020333932 5.475194918134022e-06 5.261600415234292 -0.37288794436589046 S(ph)SPLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPLLR 6 0 P56524-2;P56524;Q9UQL6-2;Q9UQL6;Q9UQL6-3;Q9UKV0-10;Q9UKV0-3;Q9UKV0-4;Q9UKV0-2;Q9UKV0;Q9UKV0-5;Q9UKV0-7 P56524-2;Q9UKV0-10 HDAC4;HDAC5;HDAC9 Histone deacetylase 4;Histone deacetylase 5;Histone deacetylase 9 1 S(0.986)S(0.014)PLLR;S(0.998)S(0.002)PLLR 87.323 0.039835 21723000.0 30246.0 30555.0 31632.0 30829.0 32394.0 28246.0 31783.0 24601.0 25947.0 22970.0 True False 35366.050414269695 33588.298469039844 32386.22684502802 29101.751078966547 26046.628242274746 26764.730035758846 28772.28415100669 23955.24981691411 26326.4257880987 27134.27916958005 1.303371657424318 1.2378548278037667 1.1935539780741944 1.0725087221624892 0.959915982270697 0.9863807278051631 1.0603666296491483 0.8828408400754602 0.9702275716840479 1.0 14.727828963104084 -5.7388100819152665 1.384334840491838 0.9715445855961353 1.2866262461164188 0.8864513458215862 0.04353139456376869 0.1396476110019934 0.5330591841331067 0.014947179320919235 0.03709066843967017 1.824693470983073e-06 5.7388100819152665 0.3150816605202835 S(ph)SPLLR ddPTM_PC-9_Lapatinib_30min_R1 2 SSPLLR 6 0 P56524-2;P56524;Q9UQL6-2;Q9UQL6;Q9UQL6-3;Q9UKV0-10;Q9UKV0-3;Q9UKV0-4;Q9UKV0-2;Q9UKV0;Q9UKV0-5;Q9UKV0-7 P56524-2;Q9UKV0-10 HDAC4;HDAC5;HDAC9 Histone deacetylase 4;Histone deacetylase 5;Histone deacetylase 9 1 S(0.978)S(0.022)PLLR;S(0.999)S(0.001)PLLR 87.75399999999999 0.039466 34672900.0 67978.0 58883.0 63176.0 48590.0 54485.0 70853.0 60789.0 56334.0 60710.0 50248.6 True False 67008.62125436164 58746.66003126072 57981.91314641232 52163.470691488306 51280.29942163145 67822.78235641 63936.356977138625 58951.4832973779 53872.20049535833 58934.003557949145 1.1370111855454181 0.9968211301561379 0.9838448034401626 0.8851166990580667 0.8701309316481122 1.1508259792620505 1.0848805972306077 1.0002965985402903 0.9141106533240424 1.0 15.846812655530373 -6.752209261704562 24.999980802936385 1.0334699277621031 0.9713643075599888 0.08765541843212588 0.08877636041704064 525.0400437403716 1422081.1228895062 0.031785192318862295 0.03136212866791083 1.7692562493688167e-07 6.752209261704562 -0.0621056202021143 S(ph)SPLPAK ddPTM_PC-9_AZD4547_30min_R2 1 SSPLPAK 7 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 S(0.999)S(0.001)PLPAK 90.37 0.015974000000000002 92682000.0 245180.0 310660.0 367930.0 311450.0 286220.0 339620.0 371200.0 386960.0 352350.0 294600.0 True False 323142.1399391918 411074.76971259026 363051.00779880886 239650.0143545329 246483.29351682682 318383.50771185977 404236.08089031506 327164.2234561915 370974.5016632184 284286.14366926113 1.1366791774246154 1.4459894682409677 1.2770619176613225 0.842988726996635 0.867025351061731 1.1199402953746052 1.4219338152499048 1.150827188527397 1.3049334620220205 1.0 18.11698425707234 -8.635523156518937 0.009957535418993014 2.557677182097929e-06 2.2756590067251343 0.02337695933464412 0.19744211700256417 12211.997988197314 71.72796953068251 8320.917031446816 8060.436959727027 2.314604768333616e-09 8.635523156518937 2.2756564490479523 S(ph)SPLPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPLPAK 7 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 S(0.925)S(0.075)PLPAK;S(0.929)S(0.071)PLPAK 89.698 0.016425 97521000.0 893320.0 1291310.0 1138790.0 955460.0 1126500.0 784490.0 1099230.0 771000.0 808330.0 738530.0 True False 1044541.4321257473 1419502.7228295144 1165943.0724851268 901928.6738431164 905770.4116479116 743349.9633842821 995102.9766639746 750762.066942025 820150.2970398831 872419.6427997353 1.1972924277285246 1.6270870727693627 1.3364475251192505 1.033824354239299 1.0382278976905521 0.8520555096613279 1.140624222387438 0.860551539775868 0.9400869223988224 1.0 19.73466272750894 -5.748923786048204 3.2376973566146225 0.9722543174555491 1.4279925941847103 0.6941238202675173 0.12457439468725579 0.12033884321980136 2.6097888260533155 0.0339305320088345 0.05920383616805365 1.7826915829574503e-06 5.748923786048204 0.4557382767291611 S(ph)SPLPAK ddPTM_PC-9_Lapatinib_30min_R1 3 SSPLPAK 7 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 S(0.924)S(0.076)PLPAK;S(0.999)S(0.001)PLPAK;S(0.952)S(0.048)PLPAK 107.01 0.0099709 207612000.0 928020.0 1456330.0 1380930.0 1152950.0 1517630.0 1472860.0 1625440.0 1578250.0 1360720.0 1159420.0 True False 914786.2646219762 1452957.957361651 1267395.265943951 1237741.7891284542 1428365.9871753787 1409869.2112043535 1709597.3298609997 1651581.2566848926 1207461.3845831673 1359824.202169963 0.67272391766685 1.0684895555198004 0.9320287607188363 0.9102219148278919 1.0504048868199574 1.0368025579736928 1.2572193722783285 1.2145549800109112 0.887954033070113 1.0 20.37498872149756 -6.39851051081965 1.7286217863976285 1.1063002261673252 0.9033508067850202 0.29276653730661284 0.13377353463944375 0.46243878013588835 2.7519675402973003 0.04946261692930147 0.059338495045619485 3.9947489307730174e-07 6.39851051081965 -0.20294941938230493 S(ph)SPLSFPSVPQEETLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPLSFPSVPQEETLR 16 0 Q9ULD5 Q9ULD5 ZNF777 Zinc finger protein 777 1 S(0.591)S(0.409)PLSFPSVPQEETLR 123.76 3.7795e-05 3866400.0 6785.3 8543.4 9444.5 7199.1 9754.2 7412.1 8348.3 6260.1 6464.5 7635.2 True False 7933.917274216233 9391.532290636398 9669.692698465713 6795.757766797105 7842.934531110586 7023.396427743687 7557.488587542049 6095.779008124223 6559.031082867537 9019.401319790057 0.8796501001466591 1.0412589436540345 1.072099173284241 0.7534599610160477 0.8695626520023998 0.7786987382780268 0.8379146596969436 0.6758518433755771 0.7272135755258987 1.0 13.138815959646664 -5.766195694908639 24.999994500893074 0.7954221597879217 1.0020283709316755 0.4542331047336302 0.09569218011791471 94.58467421410155 497156.3812363338 0.026209959619541544 0.04034882270859707 1.713185165160687e-06 5.766195694908639 0.20660621114375377 S(ph)SPLSWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPLSWR 7 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6 Q8NEY1-2 NAV1 Neuron navigator 1 1 S(0.901)S(0.099)PLSWR 75.043 0.033296 4947100.0 25303.0 30257.0 27187.0 31850.0 36152.0 32856.0 29847.0 26638.0 26929.0 22408.0 True False 29586.298142969845 33260.71499845322 27835.241187271673 30065.547759093217 29068.275119303464 31132.97352031767 27019.676086432875 25938.780725294004 27322.7856803372 26470.393018369585 1.1177128394896867 1.2565251666407589 1.0515613110827229 1.1358179585104275 1.0981429364925195 1.1761432291055296 1.0207508467170134 0.9799167208168515 1.0322017380465822 1.0 14.692091994913303 -7.335055805250691 5.91808297196818 1.0046807069374395 1.1384848045001186 0.6090490133855524 0.051491773236841495 0.1590116980732136 9.915429877404371 0.021585569685348742 0.014457467583536476 4.6232161094818187e-08 7.335055805250691 0.13380409756267908 S(ph)SPLSWR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPLSWR 7 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6 Q8NEY1-2 NAV1 Neuron navigator 1 1 S(0.629)S(0.369)PLS(0.002)WR 84.743 0.01975 5047200.0 34881.0 38600.0 41713.0 34250.0 36680.0 36919.0 33744.0 41261.0 43592.0 32500.0 True False 34383.590543608014 38510.62407157693 38283.518156836406 36768.85925465066 34522.554515654636 35340.06043239243 35491.09920933996 43178.13669068611 38682.20991588968 38117.5816964721 0.9020401875806912 1.0103113145591083 1.004353278801516 0.9646167888466475 0.9056858535925905 0.927132804851134 0.9310952486952963 1.1327617012671707 1.0148128027615624 1.0 15.218168972428535 -7.740073807750973 24.99963210616161 1.0553404797908352 0.9518386938898936 0.4781336157507935 0.04763389966462284 191.969943156277 224622.37576706227 0.0228746626923318 0.013190711723461779 1.8193916292245584e-08 7.740073807750973 -0.10350178590094161 S(ph)SPNPFITGLTR ddPTM_PC-9_AZD4547_30min_R2 1 SSPNPFITGLTR 12 0 A0A0D9SGJ6;J3KQV8;O43426 A0A0D9SGJ6 SYNJ1 Synaptojanin-1 1 S(0.983)S(0.017)PNPFITGLTR 120.6 0.00048522 5141900.0 11824.0 14251.0 16693.0 28526.0 19123.0 11607.0 18554.0 17518.0 18131.0 13453.0 True False 15583.786045521663 18857.357056505916 16471.639912987554 21949.77142230665 16468.10153700746 10881.212455130879 20205.27005613932 14810.995623593013 19089.36764482989 12982.014564774507 1.2004135388822335 1.4525755584709947 1.2688046089304061 1.6907831456194264 1.268532049077508 0.838175954959721 1.5564048210949053 1.140885765432838 1.4704472522028376 1.0 13.664226659426449 -6.5071608408194574 24.988692144787407 1.2123188986906115 1.4074016252760893 0.14819991686011336 0.22794501303099235 1416.2050308470252 2251519.2397102374 0.0695457162837401 0.07651425662026516 3.110564127350816e-07 6.5071608408194574 0.19508272658547776 S(ph)SPNPFITGLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPNPFITGLTR 12 0 A0A0D9SGJ6;J3KQV8;O43426 A0A0D9SGJ6 SYNJ1 Synaptojanin-1 1 S(0.986)S(0.014)PNPFITGLTR 104.42 0.0019122 5155600.0 13039.0 12511.0 11989.0 17158.0 18313.0 16890.0 14760.0 16675.0 15614.0 13801.0 True False 15246.245168011053 13753.00939768147 12274.863228535696 16196.692886986544 14724.699110970454 16004.258666854304 13361.825946853927 16237.298918622933 15842.325211214122 16303.012051344118 0.9351796539188635 0.843587022715081 0.7529199628803368 0.9934785569670969 0.903188874828591 0.9816749577594048 0.8195924719170099 0.995969264298264 0.9717422253827007 1.0 13.992850912722986 -7.24881778597909 0.36301019714129457 1.0056688653880368 0.848838728925427 0.2395312744390593 0.07212224721270662 2.0944790921132794 0.6818748366979516 0.0887983846102757 0.11710411475366327 5.638741871106847e-08 7.24881778597909 -0.1568301364626098 S(ph)SPNPFITGLTR ddPTM_PC-9_Lapatinib_30min_R1 2 SSPNPFITGLTR 12 0 A0A0D9SGJ6;J3KQV8;O43426 A0A0D9SGJ6 SYNJ1 Synaptojanin-1 1 S(0.985)S(0.015)PNPFITGLTR;S(0.942)S(0.058)PNPFITGLTR 129.76 0.00016585 10101100.0 41621.0 36735.0 35503.0 32317.0 37029.0 37486.0 29895.0 33699.0 38172.0 30908.0 True False 41027.476907643366 36649.942364491675 32584.080385543188 34693.699986351676 34851.02702181504 35882.81116413399 31442.816822641595 35264.778564247834 33872.667391019924 36250.40661767877 1.1317797711994462 1.0110215521449644 0.8988611004890751 0.9570568504859774 0.9613968579546561 0.9898595495101149 0.867378320862956 0.9728105655799663 0.9344079294961823 1.0 15.145709557353397 -4.860094390971655 3.0585537679604498 0.9462957637089453 1.1455173640179417 0.6807610503695256 0.03840324891357462 0.16802538653985116 2.550831851551755 0.009444204151765915 0.07450845237902777 1.3800842800095025e-05 4.860094390971655 0.19922160030899638 S(ph)SPNVANQPPS(ph)PGGK ddPTM_PC-9_AZD4547_30min_R2 2 SSPNVANQPPSPGGK 15 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 2 S(0.985)S(0.015)PNVANQPPS(1)PGGK;S(0.945)S(0.055)PNVANQPPS(1)PGGK 171.39 0.00072485 12254400.0 70523.0 79989.0 97542.0 128424.0 118915.0 123399.0 110915.0 119784.0 97894.0 113765.0 True False 92947.84703047413 105843.87997985056 96248.52934718943 98817.83093102105 102405.70487231329 115682.84102271893 120786.22012917411 101274.13516248792 103068.47698543798 109782.12197737095 0.8466574097523201 0.9641267455339207 0.8767231641507972 0.9001268070896832 0.9328085760031298 1.053749362273798 1.1002357938943046 0.9225011626516314 0.9388457348882651 1.0 16.74428360496725 -6.582179399585586 5.900861078492918 1.004019987162211 0.9020406202197813 0.45626952164942425 0.05499248312592129 0.2039095688040528 14.288346743453097 0.019485703886394704 0.019560445065059648 2.617101705170262e-07 6.582179399585586 -0.10197936694242982 S(ph)SPNVANQPPS(ph)PGGK ddPTM_PC-9_Lapatinib_30min_R1 3 SSPNVANQPPSPGGK 15 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 2 S(0.991)S(0.009)PNVANQPPS(1)PGGK;S(0.761)S(0.239)PNVANQPPS(1)PGGK;S(0.989)S(0.011)PNVANQPPS(1)PGGK 193.63 4.6552e-28 15454300.0 62426.0 58382.0 62144.0 49865.0 60488.0 61438.0 54896.0 57656.0 74907.0 45211.4 True False 61535.7937924737 58246.82006597936 57034.760202777084 53532.238444763636 56930.21476398356 58810.43995897305 57738.246271809105 60334.9082435762 66470.18485432069 53026.13024959629 1.1604805687841457 1.0984550407847802 1.0755972561888263 1.0095445055632963 1.0736256727769984 1.109084137992906 1.0888640374100973 1.1378335164111955 1.2535364082093612 1.0 15.694415846613328 -7.780932179478231 4.897479074437342 1.1481719426367034 1.0848514706090207 0.059498979505362426 0.06742685437891079 0.3705085330484737 22.741318682078663 0.03595532837091934 0.01770041497241308 1.656028552874038e-08 7.780932179478231 -0.06332047202768276 S(ph)SPNVANQPPSPGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPNVANQPPSPGGK 15 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 S(0.996)S(0.004)PNVANQPPSPGGK;S(0.993)S(0.007)PNVANQPPSPGGK 224.64 1.3571999999999998e-38 3829600.0 42226.0 49946.0 45038.0 52710.0 36323.0 28413.0 25675.0 22229.3 22071.0 20497.7 True False 49374.02779848413 54904.308798385355 46111.87672756616 49756.82958812571 29205.76889683722 26922.972261772153 23242.87812909721 21645.804428890242 22393.74662077027 24213.770750296084 2.0390887610051562 2.267482804086348 1.9043657926348505 2.054898020685906 1.206163599962228 1.111886807693632 0.9599032868027381 0.8939460380670184 0.9248351630857181 1.0 14.5635401436921 -6.344876532040145 1.992770889418118 0.9581911230849827 2.106900000005769 0.9602361867920538 0.10527626217915326 0.057146385729318544 0.4466184314284971 0.03616191201497721 0.044335163688043557 4.5198442324136326e-07 6.344876532040145 1.1487088769207865 up S(ph)SPPAPPLPPGSGSPGTPQALPR ddPTM_PC-9_AZD4547_30min_R2 1 SSPPAPPLPPGSGSPGTPQALPR 23 0 Q9Y3L3;A0A2R8Y5V0 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 S(0.497)S(0.497)PPAPPLPPGS(0.003)GS(0.001)PGT(0.001)PQALPR 121.92 1.045e-08 19899000.0 13439.0 14526.0 22374.0 29512.0 27742.0 23708.0 18954.0 21786.0 16135.0 26643.0 True False 17712.322451434855 19221.245428587823 22077.306141088087 22708.4643558548 23890.502161776985 22225.535012168777 20640.869281236646 18419.474292476156 16987.863159744644 25710.236679498055 0.6889210189791475 0.7476105983853231 0.8586971180507664 0.8832460252675567 0.9292214015605633 0.8644624819767582 0.8028268871478791 0.716425699307711 0.6607431651257868 1.0 14.650055270730993 -10.37432283324387 21.091153859906683 0.9999999999997368 0.801733923502971 0.33965599123294443 0.08537571361833406 0.0 0.0 0.09266406950990766 0.022474338016995665 4.223545398704628e-11 10.37432283324387 -0.19826607649676575 S(ph)SPPAPPLPPGSGSPGTPQALPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPPAPPLPPGSGSPGTPQALPR 23 0 Q9Y3L3;A0A2R8Y5V0 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 S(0.5)S(0.5)PPAPPLPPGSGSPGTPQALPR 78.985 0.0044464 0.0 1973.6 5073.7 7349.3 7261.5 8309.3 9968.9 7314.7 8791.6 7895.3 4846.6 True False 2307.691499623179 5577.383405084846 7524.53518437546 6854.66169710064 6681.152313809142 9446.113334754531 6621.7986621580285 8560.829815470188 8010.75382605987 5725.250214335508 0.4030726017606931 0.9741728651648418 1.3142718488590603 1.1972684931633535 1.1669625018449223 1.649904018361035 1.1565955048702754 1.4952761006033668 1.3991971575323763 1.0 12.483123030289615 -4.737539758053798 1.5993431486854994 1.3228093254096351 7.115296248251549e-11 0.7042213898620208 0.1775248038400401 0.5986622082903386 1.3629195567372037 0.047850758450523216 1.2874943720762884 1.8300385653791143e-05 4.737539758053798 -1.3228093253384823 down S(ph)SPPAPPLPPGSGSPGTPQALPR ddPTM_PC-9_Lapatinib_30min_R1 2 SSPPAPPLPPGSGSPGTPQALPR 23 0 Q9Y3L3;A0A2R8Y5V0 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 S(0.5)S(0.5)PPAPPLPPGSGSPGTPQALPR;S(0.365)S(0.365)PPAPPLPPGS(0.138)GS(0.091)PGT(0.042)PQALPR 220.1 5.6621e-38 19608700.0 30118.0 27856.0 30860.0 25845.0 29995.0 30469.0 24853.0 24450.0 29546.0 15901.6 True False 29688.511797035237 27791.50114346753 28322.8099230449 27745.72751639257 28230.75307243893 29165.911896708087 26139.76673333704 25586.036259113323 26218.21834682685 18650.170372449866 1.5918627660845002 1.4901473063496131 1.5186354525148742 1.4876929787933042 1.5136994734451088 1.5638415796883085 1.4015832676762485 1.3718928968557391 1.4057897500795244 1.0 14.186901189352527 -9.868457518868684 0.33069889675606917 0.8446955839345985 1.5504922013557072 0.9269821445098937 0.04318314658486314 1.8318720515119709 0.23057749481073178 0.3720198095533271 0.043116741603019704 1.3537625043965368e-10 9.868457518868684 0.7057966174211087 S(ph)SPPFWALPPSAPSER ddPTM_PC-9_AZD4547_30min_R2 2 SSPPFWALPPSAPSER 16 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 S(0.891)S(0.109)PPFWALPPSAPSER;S(0.961)S(0.039)PPFWALPPSAPSER 158.34 2.9674e-05 11001600.0 12225.3 10158.5 14598.4 17066.4 12410.900000000001 11177.3 10686.900000000001 14202.3 10635.1 12467.0 True False 16112.691097963114 13442.036464705308 14404.815677574883 13132.005153251564 10687.860762727923 10478.381664059136 11638.013396731449 12007.660871386865 11197.249674013034 12030.534124659473 1.339316353788173 1.1173266561085282 1.1973546251823308 1.091556286460662 0.8883945344388811 0.8709822486252853 0.9673729591836278 0.9980987333533493 0.930735872404998 1.0 13.554413075420989 -5.999110950852603 2.873582330858467 0.9406227266581455 1.2091682899616147 0.7858196874459008 0.0646439244034256 0.12209149280442247 2.0501303679302336 0.019939384561168425 0.029700324631691182 1.002049208076626e-06 5.999110950852603 0.26854556330346924 S(ph)SPPFWALPPSAPSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPPFWALPPSAPSER 16 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 S(0.981)S(0.019)PPFWALPPSAPSER;S(0.837)S(0.163)PPFWALPPSAPSER 158.89 5.0363999999999994e-05 10592500.0 14617.1 13246.099999999999 12460.0 15372.3 14825.300000000001 13478.1 18399.1 15817.8 14001.0 14422.1 True False 17091.4863291153 14561.085267574827 12757.09365481314 14511.039868669033 11920.38888930652 12771.284709160991 16656.204050051507 15402.599510344458 14205.738137710323 17036.712564719222 1.0032150430541107 0.8546886737837502 0.7488001928982116 0.8517511705115854 0.6996883256686544 0.7496331619521851 0.9776653792084455 0.9040828417943262 0.8338309450103963 1.0 14.056359356889383 -10.706946488032772 7.127118347021617 1.0000002404976913 0.8428346161041891 0.19554389092065183 0.09272189340518468 3.7456893721843424e-07 4.28579057114328e-08 0.09490091182696571 0.02301681664012555 1.9636022088618167e-11 10.706946488032772 -0.15716562439350223 S(ph)SPPGHYYQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPPGHYYQK 10 0 D6RI08;D6RDK1;D6RIV2;D6R9T5;D6RG39;D6RIT9;D6RDK6;D6RBN5;Q9NX40-3;Q9NX40-2;Q9NX40-4;Q9NX40 D6RI08 OCIAD1 OCIA domain-containing protein 1 1 S(0.836)S(0.164)PPGHYYQK;S(0.924)S(0.076)PPGHYYQK 95.477 0.0033445999999999997 12396400.0 122464.0 172160.0 216169.0 165086.0 210261.0 152213.0 168286.0 141918.0 130059.0 117013.0 True False 143194.73642574655 189250.90703419692 221323.2887854977 155836.76663603308 169061.86642121777 144230.68232432767 152344.73179486874 138192.80287455025 131960.86682754577 138226.5306256016 1.0359424907625134 1.3691359117360706 1.6011635956122692 1.127401273335365 1.2230782734404029 1.0434370425963222 1.1021381431290316 0.9997559965449564 0.954671047810446 1.0 17.07667502162841 -6.59433415601154 1.2960485084709426 1.0071889851210978 1.3230260770406796 0.4465504853014952 0.14254112478708683 0.40689467187753137 1.4285138384187785 0.06590782286444301 0.06925031323579879 2.544871417383415e-07 6.59433415601154 0.31583709191958187 S(ph)SPPGHYYQK ddPTM_PC-9_Lapatinib_30min_R1 2 SSPPGHYYQK 10 0 D6RI08;D6RDK1;D6RIV2;D6R9T5;D6RG39;D6RIT9;D6RDK6;D6RBN5;Q9NX40-3;Q9NX40-2;Q9NX40-4;Q9NX40 D6RI08 OCIAD1 OCIA domain-containing protein 1 1 S(0.856)S(0.144)PPGHYYQK;S(0.591)S(0.409)PPGHYYQK 93.839 0.0037048000000000003 11492900.0 161099.0 194768.0 197997.0 143720.0 195260.0 201177.0 177087.0 167944.0 236870.0 147992.0 True False 158801.69871806144 194317.02666251038 181718.45095052238 154289.64823586526 183775.19069593004 192573.1286764921 186255.69836665434 175747.2913497148 210191.2062483207 173572.22001305522 0.9149027344705113 1.11951685959824 1.0469328037450603 0.888907500429852 1.0587822791118728 1.109469756519838 1.0730732046444134 1.0125312180514598 1.2109726212668777 1.0 17.405176539405566 -6.506898764572794 24.77484798766922 1.0817776143777031 1.001557445773054 0.2106431846405633 0.08073971049507866 1120.228474692088 1736768.845346645 0.025005884037762226 0.02752464668826848 3.1124417726441614e-07 6.506898764572794 -0.08022016860464909 S(ph)SPPLPPPAEER ddPTM_PC-9_AZD4547_30min_R2 2 SSPPLPPPAEER 12 0 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 S(0.787)S(0.213)PPLPPPAEER;S(0.908)S(0.092)PPLPPPAEER 152.96 6.291e-05 83359000.0 78330.0 72035.0 110558.0 139877.0 122125.0 125903.0 102208.0 136917.0 104252.0 100830.0 True False 103237.31063478594 95318.90502879821 109091.92868268606 107630.51872810729 105170.05178094652 118030.26550687883 111304.31399686798 115759.62368966125 109762.54788532366 97299.97239026365 1.061020965357606 0.9796395896853957 1.1211917742908053 1.10617214048539 1.0808847032259836 1.2130554881708226 1.1439295537560263 1.1897189777748054 1.1280840599324475 1.0 16.57015177517829 -5.342189346927394 6.2549649073323375 1.1321491331777678 1.0208438444375982 0.3213682006729194 0.0584554983426091 0.21952093608154524 13.689830919104665 0.014954242033685379 0.03171858697777611 4.547897343199455e-06 5.342189346927394 -0.11130528874016954 S(ph)SPPLPPPAEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPPLPPPAEER 12 0 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 S(0.9)S(0.1)PPLPPPAEER;S(0.99)S(0.01)PPLPPPAEER 158.34 6.9368e-05 66157000.0 98417.0 103534.0 119368.0 132338.0 131268.0 99063.0 122139.0 121999.0 105876.0 100503.0 True False 115077.05427564579 113812.17128763147 122214.18582566074 124923.530905585 105546.9777152225 93867.96188955528 110569.10971021655 118796.65551862538 107424.23620228672 118723.39831868971 0.9692870647683448 0.9586330318992806 1.0294026919411512 1.0522233416049316 0.8890158065716945 0.7906441629777572 0.9313169204727061 1.0006170409622122 0.9048278412139736 1.0 16.857244767560665 -6.272421838713994 24.653718152363005 0.9135921701820036 1.0011910094467917 0.3038898197982749 0.06113924863704365 788.1358115820251 1769224.431991577 0.020413641546637835 0.023360110920240488 5.340453786811041e-07 6.272421838713994 0.08759883926478818 S(ph)SPPLPPPAEER ddPTM_PC-9_Lapatinib_30min_R1 2 SSPPLPPPAEER 12 0 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 S(0.96)S(0.04)PPLPPPAEER;S(0.946)S(0.054)PPLPPPAEER 121.6 0.00043919 76116000.0 89629.0 84960.0 98306.0 80817.0 90959.0 102028.0 88170.0 78915.0 109810.0 78549.0 True False 88350.87402405428 84763.28033992676 90223.66015213393 86760.5517776089 85608.97045227452 97664.50027888438 92735.01118087674 82581.67899337127 97442.0414494368 92126.08999003666 0.9590212070609893 0.9200789955276927 0.9793497169139765 0.9417587546263165 0.9292586981769554 1.060117717895622 1.006609649784398 0.896398392706153 1.0577029966209903 1.0 16.49132216310769 -6.713965963238539 24.999765150150342 0.9978439299710014 0.9460882791221537 0.29212693533754897 0.044817286701360516 176.75268543408316 93078.33669921268 0.014731056634316052 0.014731020247416033 1.9321197362137437e-07 6.713965963238539 -0.0517556508488477 S(ph)SPPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPPLR 6 0 E9PJN1;O75676-2;O75676;A0A0A6YYC0 E9PJN1 RPS6KA4 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-4 1 S(0.987)S(0.013)PPLR 87.75399999999999 0.039466 30407000.0 13078.0 23071.0 17147.0 17589.0 17622.0 16460.0 17443.0 12570.0 14140.0 9965.5 True False 15291.847097725946 25361.336409072777 17555.84951035962 16603.54535430739 14169.095600585455 15596.808623826046 15790.672763616061 12240.0508190159 14346.770749748153 11772.166263145407 1.2989832759667561 2.1543474533204967 1.4913015258135567 1.4104069704050446 1.2036098780684068 1.3248885782945723 1.3413565872792004 1.0397449836684076 1.2187026949035662 1.0 13.523092202859651 -5.806306603420622 1.9952524681419193 1.2061022340264718 1.7337188516745226 0.4658262560281702 0.2230413933201206 0.26576600671021366 2.161041270666279 0.06556509868151929 0.12398273030312344 1.5620444803914292e-06 5.806306603420622 0.5276166176480508 S(ph)SPPLRTPDVLESSGPAVR ddPTM_PC-9_AZD4547_30min_R2 1 SSPPLRTPDVLESSGPAVR 19 1 E9PJN1;O75676-2;O75676;A0A0A6YYC0 E9PJN1 RPS6KA4 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-4 1 S(0.493)S(0.493)PPLRT(0.014)PDVLESSGPAVR 66.041 0.0047902000000000005 74820000.0 10946.0 10085.0 17560.0 18724.0 15300.0 14633.0 5258.6 11104.0 11196.0 12616.0 True False 14426.600309056164 13344.779027076149 17327.142926499815 14407.471082916269 13175.859097223982 13717.996196771797 5726.605212741953 9388.13194453572 11787.797702912992 12174.317680011542 1.185002781120337 1.0961418436604735 1.4232537199968474 1.1834315040563825 1.0822667391747816 1.126797949366374 0.47038407927733034 0.7711423499281334 0.9682512000049778 1.0 13.571553297052276 -7.087348929672143 8.119252890423697 0.7833974873177162 1.191387027925496 0.5789497471462306 0.15941660609608357 0.22444457972345244 18.934593011002313 0.061739380467110076 0.04784494391108313 8.178074646667455e-08 7.087348929672143 0.4079895406077797 S(ph)SPPLRTPDVLESSGPAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSPPLRTPDVLESSGPAVR 19 1 E9PJN1;O75676-2;O75676;A0A0A6YYC0 E9PJN1 RPS6KA4 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-4 1 S(0.484)S(0.484)PPLRT(0.032)PDVLESSGPAVR;S(0.492)S(0.492)PPLRT(0.016)PDVLESSGPAVR;S(0.5)S(0.5)PPLRTPDVLESSGPAVR 78.22800000000001 0.0014939 98951000.0 29016.0 14872.3 27198.5 33246.7 47130.1 40849.0 29224.1 41728.5 37589.3 26087.5 True False 33927.83570787705 16348.72365639343 27847.01539088565 31383.99518625569 37895.29523125371 38706.80652944533 26455.781683838355 40633.17109000039 38138.972400531005 30816.95724146362 1.1009469702682977 0.5305106382922367 0.9036263759816633 1.0184001924767943 1.2296897105813653 1.2560229819628679 0.8584813054886098 1.3185328704460557 1.237596953576447 1.0 14.911436801773357 -5.8339394147121935 2.6580717046777176 1.154618444639072 0.8017808790560332 0.35790685044054615 0.18200276790300646 0.2647013545359227 3.7975140699885084 0.05253336634305431 0.08927053503719555 1.465752303215961e-06 5.8339394147121935 -0.3528375655830387 S(ph)SPPLRTPDVLESSGPAVR ddPTM_PC-9_Lapatinib_30min_R1 2 SSPPLRTPDVLESSGPAVR 19 1 E9PJN1;O75676-2;O75676;A0A0A6YYC0 E9PJN1 RPS6KA4 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-4 1 S(0.489)S(0.489)PPLRT(0.023)PDVLESSGPAVR;S(0.5)S(0.5)PPLRTPDVLESSGPAVR 131.56 1.3267999999999999e-05 133442000.0 56617.0 38345.0 33788.0 30837.0 26013.4 34118.0 24353.0 24032.0 34350.0 31064.0 True False 55809.631197713796 38256.21450840979 31010.08106545175 33104.855849216416 24483.34295631217 32658.85267294254 25613.879179855845 25148.614453129303 30481.141278464173 36433.37100982182 1.5318272685409335 1.0500322492282297 0.8511449862021265 0.9086410324285367 0.6720032288451122 0.896399420853433 0.7030334682165638 0.6902631778527895 0.836626983274399 1.0 15.15297286664647 -4.036437835872135 1.0254278707709588 0.7894991231593256 3.897578877430673 0.8240173792100619 0.10024402708063965 2.5912449544727263 0.7316148649555048 0.030026465753854766 12.762468135143768 9.195220841151891e-05 4.036437835872135 3.1080797542713476 S(ph)SPPPGYIPDELHQVAR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPPPGYIPDELHQVAR 17 0 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 S(0.498)S(0.498)PPPGY(0.004)IPDELHQVAR 78.244 0.0040571999999999995 4171100.0 7955.0 7798.3 8815.8 9216.8 9372.1 8570.3 9298.1 10674.0 11015.0 7161.0 True False 7841.560241231669 7780.243515476124 8090.998953972106 9894.634218343474 8820.851504257545 8203.76824734508 9779.510122047286 11169.953007352784 9774.374706907804 8398.769308567285 0.9336558670843326 0.9263551872462761 0.963355303225053 1.1781052502835516 1.0502552433794925 0.9767821862873063 1.1643979924620094 1.3299511627207945 1.163786543932968 1.0 13.035962226540926 -5.625945847219351 0.5853143372724465 1.166391056403687 0.8579887350919182 0.37129792702094433 0.10077302696652056 1.7511268966070022 0.8788765928564722 0.06658365981559215 0.3257721245367179 2.3662147256840937e-06 5.625945847219351 -0.3084023213117688 S(ph)SPPPGYVPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPPPGYVPER 11 0 J3KRN4;J3QRB6;Q99759;Q99759-2 J3KRN4 MAP3K3 Mitogen-activated protein kinase kinase kinase 3 1 S(0.989)S(0.011)PPPGYVPER 94.465 0.006621800000000001 4199200.0 15525.0 18614.0 21274.0 20799.0 21243.0 16017.0 23049.0 12575.0 19138.0 12573.0 True False 18153.07586727292 20461.874904359593 21781.252842094276 19633.699461267814 17080.586644151444 15177.040323682979 20865.631859690802 12244.919574313843 19417.857044461125 14852.385372186767 1.22223302266767 1.377682735237762 1.4665154651105952 1.3219223019916213 1.1500231253181261 1.021858775096435 1.4048673890972898 0.8244412777791384 1.3073897934821879 1.0 13.858407033690574 -6.25337643325738 3.8170516489677695 1.116330963280735 1.3620401985126442 0.32947281321112487 0.16083843359640024 0.2570323488762202 8.532878921690456 0.04763533095609937 0.05910737195382847 5.579863394714578e-07 6.25337643325738 0.24570923523190924 S(ph)SPPSAGNSPSSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPPSAGNSPSSLK 14 0 P57682;P57682-2 P57682 KLF3 Krueppel-like factor 3 1 S(0.853)S(0.147)PPSAGNSPSSLK;S(0.882)S(0.118)PPSAGNSPSSLK 136.6 3.1213e-05 14992000.0 37122.0 43622.0 34973.0 39428.0 45576.0 33336.0 36468.0 32392.0 27998.0 26869.0 True False 43406.021407079264 47952.503872245354 35806.88895584111 37218.97698730068 36645.709970053504 31587.801475325934 33013.48703454401 31541.74432216094 28407.417782987894 31740.137005113025 1.3675436057534023 1.5107844009785047 1.1281264775282152 1.1726155114360428 1.1545542466987537 0.99520053962708 1.0401179752067817 0.9937494698614525 0.894999847619175 1.0 14.954020735075114 -5.375959560279865 0.5327591557243435 0.9591530070838229 1.6166560908803973 0.8114474433470282 0.0777503153731085 0.9551359418260225 0.32349610262989664 0.0495848942765169 0.36304843734877296 4.207658065457582e-06 5.375959560279865 0.6575030837965744 S(ph)SPPSPYMGFSGNSK ddPTM_PC-9_AZD4547_30min_R2 1 SSPPSPYMGFSGNSK 15 0 V9GZ20;V9GXZ5;Q70EL4-2;Q70EL4-3;Q70EL4-4;Q70EL4 V9GZ20 USP43 Ubiquitin carboxyl-terminal hydrolase 43 1 S(0.86)S(0.14)PPSPYMGFSGNSK 109.07 0.0036049 0.0 7280.7 9122.9 12043.0 17864.0 15995.0 13518.0 12994.0 17286.0 13276.0 15403.0 True False 9595.811152032271 12071.699016967077 11883.30195124358 13745.73079604872 13774.370343797224 12672.71732303431 14150.440827286531 14614.845892763367 13977.742256508833 14863.745658308326 0.6455849940266262 0.8121572646945429 0.7994823259506745 0.9247824277970826 0.9267092333551753 0.8525924497336036 0.9520104254055853 0.9832545731562735 0.9403916467512853 1.0 13.859510099848968 -3.6647378236522954 0.4348042278213145 0.9654855875256309 4.0029004780397536e-15 0.8508995437439831 0.03951657141813504 4.955144550537723 0.3442985782318425 0.02750219276724421 3.0280794224562912 0.0002164024515053392 3.6647378236522954 -0.9654855875256269 S(ph)SPPSPYMGFSGNSK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPPSPYMGFSGNSK 15 0 V9GZ20;V9GXZ5;Q70EL4-2;Q70EL4-3;Q70EL4-4;Q70EL4 V9GZ20 USP43 Ubiquitin carboxyl-terminal hydrolase 43 1 S(0.609)S(0.391)PPSPYMGFSGNSK 144.88 9.544e-05 3520700.0 19387.0 20015.0 18638.0 18741.0 15268.0 13138.0 12754.0 12429.0 15797.0 8899.3 True False 19110.537824859624 19968.656497217933 17105.65558476056 20119.275658143302 14369.96625804294 12576.118366173838 13414.339714198723 13006.496714295283 14017.775510215377 10437.532147428126 1.8309440924278813 1.9131588018282977 1.6388601580475612 1.9275893356746037 1.3767589938952944 1.2048938569518728 1.2852022417486972 1.2461275836645127 1.3430162716834788 1.0 13.349493020620088 -6.387633826006234 4.006536989127407 1.2396206891588655 1.8195242124844762 0.8668143339662778 0.11333315019779856 0.07992368209634206 2.2006271906339925 0.034531886235560694 0.039338498505891044 4.0960587204910973e-07 6.387633826006234 0.5799035233256107 S(ph)SPQHSLSNPLPR ddPTM_PC-9_AZD4547_30min_R2 1 SSPQHSLSNPLPR 13 0 Q86UE8-2;Q86UE8 Q86UE8-2 TLK2 Serine/threonine-protein kinase tousled-like 2 1 S(0.983)S(0.017)PQHSLSNPLPR 125.84 0.00013662 5291800.0 5802.1 12790.0 18785.0 35715.0 30537.0 24497.0 23377.0 29748.0 21357.0 22645.0 True False 7647.047108822836 16924.117377918083 18535.898626099035 27481.458541249438 26297.464656988817 22965.198717441308 25457.507712750306 25151.130141034653 22485.887418820344 21852.20544260155 0.3499439509164911 0.7744809750380616 0.8482392623841404 1.2576057191771355 1.2034238249344433 1.0509327663865884 1.1649857392938523 1.1509652976262867 1.0289985364581742 1.0 14.415491271199238 -4.869790853723368 1.2284949831998684 1.1268798742240949 0.09750230033590325 0.8556411773272681 0.09722058567490915 0.4359223530646812 0.6321436415209392 0.02974980075653781 0.5513850549382827 1.3496126686715696e-05 4.869790853723368 -1.0293775738881916 down S(ph)SPQHSLSNPLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPQHSLSNPLPR 13 0 Q86UE8-2;Q86UE8 Q86UE8-2 TLK2 Serine/threonine-protein kinase tousled-like 2 1 S(0.79)S(0.21)PQHSLSNPLPR;S(0.871)S(0.125)PQHS(0.001)LS(0.004)NPLPR 104.81 0.002956 4042300.0 28682.0 27202.0 34936.0 44306.0 54050.0 44939.0 44379.0 40361.0 42576.0 30131.0 True False 33537.296104677735 29902.434788244864 35769.00673551782 41823.67846199006 43459.29050117149 42582.31972941186 40175.09984386386 39301.56651601441 43198.59345412145 35593.511783135255 0.9422306039655298 0.8401091460273693 1.004930532099553 1.1750365829821476 1.2209891163861826 1.1963506154958277 1.128719753438306 1.104177827562272 1.2136648307512494 1.0 15.119326660870582 -5.575152362253703 3.4938094347440387 1.1566383873781578 0.8938092589365152 0.7145603819546391 0.06581807839301987 0.11003074745600583 2.7464448937346035 0.017752612355505952 0.03457509145563347 2.6597917691856523e-06 5.575152362253703 -0.26282912844164263 S(ph)SPQHSLSNPLPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPQHSLSNPLPR 13 0 Q86UE8-2;Q86UE8 Q86UE8-2 TLK2 Serine/threonine-protein kinase tousled-like 2 1 S(0.499)S(0.499)PQHS(0.002)LSNPLPR 84.62 0.0048157 3339900.0 14339.0 11356.0 17892.0 14833.0 18966.0 14275.0 13103.0 12977.0 17979.0 10123.0 True False 14134.52323054945 11329.705879710555 16420.988825117285 15923.86830143746 17850.457168590656 13664.491526650289 13781.409226528602 13579.958794867624 15954.015692736739 11872.747061950378 1.1905015037208686 0.9542615386812918 1.383082511522801 1.3412117868214393 1.5034816353325309 1.1509123756575317 1.1607599449915915 1.1437924790285894 1.343750996251403 1.0 13.535366157336941 S(ph)SPQLDPLR ddPTM_PC-9_AZD4547_30min_R2 2 SSPQLDPLR 9 0 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 1 S(0.944)S(0.056)PQLDPLR;S(0.961)S(0.039)PQLDPLR 118.9 0.0017695999999999999 98895000.0 77862.0 87453.0 89609.0 106339.0 96704.0 101343.0 84854.0 98363.0 83972.0 84037.0 True False 102620.4963697911 115720.4720133754 88420.72611051958 81824.18647117246 83278.31883254567 95006.00618939663 92405.84161602055 83163.25850687751 88410.58848776441 81094.89020887206 1.2654372686796493 1.4269761228521298 1.0903365906628484 1.0089931222598858 1.026924367466925 1.1715412148002717 1.1394779791675584 1.0255055317625814 1.0902115812728728 1.0 16.307323392604005 -5.279760819434878 17.876436904888525 1.0725494129467497 1.3462056889992307 0.7470930759168501 0.06446094913739003 8.659375148608618 8449.690303726202 0.017038653995386198 0.03581309571971411 5.250965689572817e-06 5.279760819434878 0.273656276052481 S(ph)SPQLDPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPQLDPLR 9 0 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 1 S(0.631)S(0.369)PQLDPLR;S(0.633)S(0.367)PQLDPLR 135.8 0.0010382 24969000.0 143685.0 158550.0 142849.0 136268.0 162113.0 119238.0 121596.0 80158.0 94532.0 89323.0 True False 168008.03259189127 174289.79617955402 146255.06191784903 128633.34574681694 130348.12138790777 112984.94937349764 110077.54660119607 78053.93743442147 95914.35166302655 105516.55281952092 1.5922433789062262 1.6517768210042378 1.3860864291881165 1.219082146919979 1.2353333946651917 1.0707793834655583 1.043225386536996 0.7397316852070364 0.9089981533710801 1.0 16.687109812681193 -5.946130439390531 0.5733936790112089 0.8709582077626937 1.7560020904732712 0.8915113291573195 0.09137860006194405 0.39136060203527157 0.2291253211557441 0.06437288471691902 0.1981741126548853 1.1320603003531949e-06 5.946130439390531 0.8850438827105774 S(ph)SPQLDPLR ddPTM_PC-9_Lapatinib_30min_R1 3 SSPQLDPLR 9 0 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 1 S(0.5)S(0.5)PQLDPLR;S(0.979)S(0.021)PQLDPLR;S(0.803)S(0.197)PQLDPLR 125.36 0.0014290999999999998 97182400.0 105976.7 148970.4 162287.0 138434.0 158363.0 147219.0 143737.6 154639.0 137934.2 127369.3 True False 104465.45282425315 148625.4681915143 148944.3893059362 148614.89816228618 149048.39969363724 140922.7865542508 151179.62961452187 161824.09247742442 122398.5978844814 149384.91379607588 0.699303900036774 0.9949161827304843 0.9970510777899498 0.9948454257245759 0.9977473354310864 0.9433535353283622 1.012014036577321 1.0832693099005242 0.8193504603253761 1.0 17.188674933872193 -4.76037335324227 24.98934400617752 0.9861226044257075 0.6993035584969611 0.6410587595455279 0.0635220889037023 15.583136032585504 365122.4369065937 0.014793511143831444 0.0880156195208918 1.7363075222591824e-05 4.76037335324227 -0.2868190459287464 S(ph)SPQLDPLRK ddPTM_PC-9_AZD4547_30min_R2 3 SSPQLDPLRK 10 1 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 1 S(0.787)S(0.213)PQLDPLRK;S(0.5)S(0.5)PQLDPLRK;S(0.855)S(0.145)PQLDPLRK 98.40700000000001 0.0021872 459071000.0 328446.0 376766.0 366768.0 296088.0 346814.0 470105.0 393527.0 441569.0 382867.0 296431.0 True False 432884.9958987992 498548.2414393027 361904.41667804634 227829.486113999 298664.86254540045 440709.26003440213 428550.1406371863 373334.65729617246 403104.56798152777 286053.0409165749 1.5133032479282285 1.7428524438749118 1.2651654235816807 0.7964588853311427 1.044089101756844 1.540655742103897 1.498149221780759 1.305123889261686 1.4091951852352098 1.0 18.125923155609698 -1.5228812388600803 0.023600601401111906 1.0855810489165524e-09 3.077541785157782 0.1124411793599982 0.2596652757844996 7109.093465930911 12.9578741628605 593.8350422707277 1191.2961041625726 0.029999827750108187 1.5228812388600803 3.077541784072201 S(ph)SPQLDPLRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSPQLDPLRK 10 1 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 1 S(0.793)S(0.207)PQLDPLRK;S(0.814)S(0.186)PQLDPLRK;S(0.964)S(0.036)PQLDPLRK 101.56 0.0016305 329727000.0 512544.0 775270.0 681650.0 569230.0 613770.0 453182.0 566280.0 306476.0 359724.0 409389.0 True False 599307.5759945587 852233.6820190664 697903.121172021 537337.888568559 493506.1744848111 429416.338138684 512637.8588878356 298431.32973816385 364984.28296905314 483607.98497846 1.2392425158597247 1.7622407166354481 1.4431174481188638 1.1111021845358737 1.0204673822885533 0.8879430271562002 1.06002769766233 0.6170934703475917 0.7547110351896064 1.0 18.88347853993725 -6.014075840533194 1.4096836016913918 0.8525993140541126 1.5350783859793524 0.7089433814505028 0.16975173254470707 0.21822402928529414 0.8782855177316483 0.060848106722459175 0.10750800821218445 9.68108781358374e-07 6.014075840533194 0.6824790719252398 S(ph)SPQLDPLRK ddPTM_PC-9_Lapatinib_30min_R1 2 SSPQLDPLRK 10 1 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 1 S(0.5)S(0.5)PQLDPLRK;S(0.5)S(0.5)PQLDPLRK 80.318 0.008168600000000002 530610000.0 155516.0 217915.0 182713.0 164378.0 209412.0 196123.0 154091.0 195501.0 176431.0 148107.0 True False 153298.31332185812 217410.43120615798 167691.04243257624 176466.90646893304 197094.79787983274 187735.2764750426 162069.07800694657 204584.6901714889 156559.4828792057 173707.0976098277 0.8825103604355259 1.2515921007125141 0.9653666703316612 1.0158877149931103 1.1346387142023253 1.0807576607878413 0.9330020490640982 1.1777566546590799 0.9012843172986625 1.0 17.406297177692387 -8.289837898777002 24.992827026832433 0.9506421604287641 1.056859378798866 0.12722360629724028 0.10946138983472327 1631.1080391321077 1435482.0104576244 0.09717602084300675 0.025111564581679575 5.130528461862605e-09 8.289837898777002 0.1062172183701019 S(ph)SPRPTAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPRPTAEK 9 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 S(0.959)S(0.041)PRPTAEK;S(0.576)S(0.424)PRPTAEK 67.749 0.030304 24256000.0 187324.0 226361.0 209621.0 213104.0 298597.0 312986.0 194170.0 237946.0 267700.0 259186.0 True False 219034.25338235288 248832.62411226722 214619.15963206996 201164.47377249028 240089.0613464991 296572.46317963634 175776.8119309367 231700.16962462626 271614.6060613565 306174.3700847531 0.7153905577456445 0.8127153949672112 0.7009703639552212 0.6570258435309438 0.7841579335332324 0.9686390898674543 0.5741068786465678 0.7567588677017237 0.8871239156503204 1.0 18.223993994050403 -8.460533748302963 2.871668611482442 0.9972214484616554 0.7469034210237793 0.41583522173142273 0.09808739443172447 0.2400828816662147 4.220733912214804 0.09508853496620269 0.02557031036920869 3.4631097231209297e-09 8.460533748302963 -0.2503180274378761 S(ph)SPSARPPDVPGQQPQAAK ddPTM_PC-9_AZD4547_30min_R2 5 SSPSARPPDVPGQQPQAAK 19 1 A0A0A6YYC7;Q96JP5-2;Q96JP5 A0A0A6YYC7 ZFP91-CNTF;ZFP91 E3 ubiquitin-protein ligase ZFP91 1 S(0.5)S(0.5)PSARPPDVPGQQPQAAK;S(0.484)S(0.484)PS(0.033)ARPPDVPGQQPQAAK;S(0.823)S(0.17)PS(0.007)ARPPDVPGQQPQAAK;S(0.492)S(0.492)PS(0.016)ARPPDVPGQQPQAAK;S(0.841)S(0.159)PSARPPDVPGQQPQAAK 171.52 8.885599999999999e-28 100249000.0 131594.0 140698.0 157836.0 203669.0 209125.0 199671.0 160813.0 190697.0 160418.0 181216.0 True False 173438.15467476167 186175.87700065062 155742.9915117895 156716.25870468232 180091.60351025924 187185.5408054135 175125.04546393943 161229.16043111772 168897.3679801622 174871.68299785728 0.9918023987730868 1.0646427929839954 0.890612984571652 0.896178592314472 1.0298500044313403 1.0704165339777 1.001448847873702 0.9219855248553493 0.965836006634829 1.0 17.415937166749345 -4.422841115413244 24.61961583123512 0.9820544527220813 3.8219021502742487 0.002146638786737154 0.061007221647465755 2547.5478742762125 6210338.968235215 0.015951785947394877 3639804.585739814 3.7771034920042716e-05 4.422841115413244 2.8398476975521674 S(ph)SPSARPPDVPGQQPQAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SSPSARPPDVPGQQPQAAK 19 1 A0A0A6YYC7;Q96JP5-2;Q96JP5 A0A0A6YYC7 ZFP91-CNTF;ZFP91 E3 ubiquitin-protein ligase ZFP91 1 S(0.934)S(0.066)PSARPPDVPGQQPQAAK;S(0.859)S(0.137)PS(0.004)ARPPDVPGQQPQAAK;S(0.5)S(0.5)PS(0.001)ARPPDVPGQQPQAAK;S(0.497)S(0.497)PS(0.006)ARPPDVPGQQPQAAK;S(0.499)S(0.499)PS(0.002)ARPPDVPGQQPQAAK 191.71 6.2157e-12 113897200.0 123567.2 169704.4 136669.3 152312.0 171951.0 152130.1 152834.0 125286.2 130891.0 103759.4 True False 144484.68639655286 186551.53129469207 139928.0144332066 143778.45244216625 138258.4359105814 144152.1297462647 138356.4570976606 121997.57000170187 132805.0332535562 122570.1578610416 1.1787917133985897 1.5219979687566894 1.1416156826023158 1.1730298381859685 1.1279942713896614 1.1760785191260883 1.1287939863348795 0.9953284888480858 1.0835021800666842 1.0 16.903248243461213 -5.79756204343897 0.37170505268180526 1.0076068931021283 1.4377410814071525 0.48375454378262195 0.09960985327574796 2.3913600475280385 0.455337628623414 0.09715064596671491 0.431663502924858 1.5938151715374358e-06 5.79756204343897 0.43013418830502426 S(ph)SPSARPPDVPGQQPQAAK ddPTM_PC-9_Lapatinib_30min_R1 6 SSPSARPPDVPGQQPQAAK 19 1 A0A0A6YYC7;Q96JP5-2;Q96JP5 A0A0A6YYC7 ZFP91-CNTF;ZFP91 E3 ubiquitin-protein ligase ZFP91 1 S(0.497)S(0.497)PS(0.006)ARPPDVPGQQPQAAK;S(0.499)S(0.499)PS(0.001)ARPPDVPGQQPQAAK;S(0.499)S(0.499)PS(0.002)ARPPDVPGQQPQAAK;S(0.5)S(0.5)PSARPPDVPGQQPQAAK;S(0.494)S(0.494)PS(0.011)ARPPDVPGQQPQAAK;S(0.5)S(0.5)PSARPPDVPGQQPQAAK 152.59 1.277e-05 173374000.0 229583.0 226510.0 258259.0 221599.0 243591.0 223126.0 229567.0 231461.0 245044.0 198467.0 True False 226309.1043196341 225985.53001173338 237025.94192856972 237896.12969259336 229263.45629833246 213583.42111211005 241452.85598004193 242215.52304992368 217444.56429228466 232771.75650934575 0.9722360981992582 0.9708460055490457 1.018276209635653 1.022014583126806 0.984928153382421 0.9175658779012338 1.0372944707763445 1.0405709295758085 0.9341535569138273 1.0 17.82855649309616 -6.6896631258186146 0.003921540805891793 1.3383021508772786 0.6438903635991762 0.0012863403391644157 0.03971345531615764 191481.79562121004 279.872809490338 24498.444134779646 25057.377066514877 2.043322297353347e-07 6.6896631258186146 -0.6944117872781024 S(ph)SPSHTTNGCQGEK ddPTM_PC-9_AZD4547_30min_R2 1 SSPSHTTNGCQGEK 14 0 Q8N8R5 Q8N8R5 C2orf69 UPF0565 protein C2orf69 1 S(0.333)S(0.333)PS(0.333)HTTNGCQGEK 93.649 0.0020805 1774300.0 2256.6 2008.6 5588.6 6073.9 5812.1 6008.8 2784.5 6266.4 3777.5 5687.6 True False 2974.1518598041425 2657.8406696861816 5514.491512473633 4673.6561958195425 5005.190239148728 5633.068786111006 3032.315105708739 5298.071867546706 3977.170938080906 5488.478855170704 0.5418900096521625 0.48425815965059715 1.004739502144282 0.8515394372734959 0.9119448887797629 1.0263442630928756 0.5524873440756705 0.9653078762534331 0.7246399308496939 1.0 12.422190642966205 -5.251075463602263 24.949620242090738 0.8720940551712817 0.5130740287259482 0.5251184234194971 0.13928358851870845 519.0056858047097 1249424.5098656283 0.03418262626830575 0.08832950551442448 5.609504960393418e-06 5.251075463602263 -0.3590200264453335 S(ph)SPSILAVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPSILAVQR 10 0 O14646;O14646-2 O14646 CHD1 Chromodomain-helicase-DNA-binding protein 1 1 S(0.499)S(0.499)PS(0.003)ILAVQR 91.469 0.0080515 5126000.0 20611.0 18590.0 17563.0 16891.0 28327.0 17666.0 18074.0 16071.0 13931.0 13507.0 True False 24100.03521419403 20435.492342970072 17981.768528048404 15944.652031360869 22776.527697070935 16739.56386078439 16361.899875571677 15649.153278632031 14134.714520137302 15955.712178646836 1.5104330627401612 1.2807634102549446 1.1269800010627538 0.9993068220859005 1.4274842415089588 1.0491267123247914 1.0254571962929009 0.9807868870669988 0.8858717405954131 1.0 13.961785383884102 -1.522878745280339 0.2916024320286404 0.9601246098016504 5.012708802788446 0.5828413956415145 0.12742956089769245 41.76202413202473 0.5931126784175196 0.14229981066897754 87.42977415920471 0.029999999999999905 1.522878745280339 4.052584192986796 S(ph)SPSILAVQR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPSILAVQR 10 0 O14646;O14646-2 O14646 CHD1 Chromodomain-helicase-DNA-binding protein 1 1 S(0.5)S(0.5)PSILAVQR 160.91 0.00055381 5007300.0 20385.0 23238.0 30323.0 19293.0 22744.0 23469.0 20216.0 16464.0 26450.0 12769.0 True False 20094.306161848846 23184.19383873846 27829.959990164945 20711.871579561313 21406.242636424442 22465.28557891109 21262.685562352322 17228.97754478699 23470.922469152163 14976.104636376998 1.3417578635928946 1.5480790500370833 1.858290968571754 1.3829945825333059 1.4293598473149434 1.5000753616760163 1.4197741053908772 1.1504311677241996 1.5672247916952469 1.0 13.870374799568369 -10.196116013460914 0.22043732122069779 0.7058667011033875 1.6004626007029596 0.42466536908225727 0.16845649336995797 13.124691352398719 0.7708744592618525 2.9547878064259945 0.4148091278610462 6.366254358876405e-11 10.196116013460914 0.8945958995995722 S(ph)SPSPALEQPFR ddPTM_PC-9_AZD4547_30min_R2 1 SSPSPALEQPFR 12 0 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 S(0.963)S(0.025)PS(0.012)PALEQPFR 112.02 0.0010031 5127900.0 10324.0 13826.0 16273.0 27750.0 19853.0 15486.0 15322.0 21836.0 17470.0 16258.0 True False 13606.81724745988 18294.984117833887 16057.209387410694 21352.66623322615 17096.75363772469 14517.657971927007 16685.628317352955 18461.74794136185 18393.428534288127 15688.812368550072 0.8672942812890173 1.1661165732664487 1.023481510914052 1.3610122762402264 1.0897417367293518 0.9253509845671447 1.063536737223087 1.1767460472897506 1.1723913896223115 1.0 13.937448525045214 -4.753562362306369 24.9584587116732 1.111718784853102 0.8672938288844392 0.2858820527541033 0.11437676931962515 389.0453099188794 1232595.5286192629 0.02920665732369849 0.3108750331745869 1.763752481106146e-05 4.753562362306369 -0.24442495596866287 S(ph)SPSPALEQPFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPSPALEQPFR 12 0 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 S(0.867)S(0.039)PS(0.094)PALEQPFR 110.98 0.0011282 2988400.0 8412.5 12872.0 12122.0 12080.0 14077.0 11592.0 12408.0 13458.0 13513.0 10275.0 True False 9836.570095551273 14149.84709191559 12411.034452941 11403.19676388842 11318.712902590025 10984.095113450281 11232.624413859317 13104.741759929668 13710.602060915617 12137.776163144747 0.8104095810745896 1.1657693222981251 1.0225130440801815 0.939479902299829 0.9325194953716701 0.9049512007646414 0.92542688733758 1.079665795759278 1.12958105971229 1.0 13.567216500295205 -7.7733961247024865 24.779209300406766 1.078467640770687 0.9641708204458448 0.23833942838838307 0.09114767536328895 306.8754215047381 635958.787817219 0.049949108234350746 0.024295385599522806 1.6850154034480476e-08 7.7733961247024865 -0.11429682032484223 S(ph)SPSPALEQPFR ddPTM_PC-9_Lapatinib_30min_R1 2 SSPSPALEQPFR 12 0 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 S(0.606)S(0.008)PS(0.386)PALEQPFR;S(0.879)S(0.017)PS(0.104)PALEQPFR 132.14 9.581100000000001e-05 11803400.0 46209.0 52955.0 54033.0 51080.0 51219.0 48189.0 47713.0 45816.0 53439.0 40586.0 True False 45550.05118630726 52832.385951045486 49590.61531341168 54836.59359788485 48206.399120428425 46128.0688040456 50183.34567849799 47944.77861953112 47420.13708238275 47601.236022554374 0.9569090005294143 1.1098952541066893 1.0417925973584952 1.1519993634598527 1.01271318033816 0.9690519124795256 1.054244592613523 1.0072170940438179 0.9961954992075035 1.0 15.538711414856994 -6.483652972661455 24.97441497615027 1.0068529633603975 1.0686368263882762 0.2424161604341556 0.0506861454043661 723.6706674320797 460749.2605861378 0.015132071459855618 0.017154800405160868 3.283575657021646e-07 6.483652972661455 0.06178386302787864 S(ph)SPSPEVVKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPSPEVVKPK 11 1 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 S(0.917)S(0.012)PS(0.071)PEVVKPK 103.43 0.014031 3800900.0 11671.0 10392.0 9022.4 13650.0 13249.0 9914.4 12734.0 9552.8 10409.0 8493.6 True False 13646.669787242661 11423.649081664604 9237.528233642548 12885.234753897095 10652.953558742302 9394.471410696291 11527.743333823717 9302.049122028247 10561.211933106688 10033.42244469939 1.3601211214277271 1.1385595637607846 0.9206757000969984 1.2842312605609767 1.0617467387083066 0.9363177382867345 1.1489343140249983 0.9271062963109339 1.0526031362993318 1.0 13.292526179097822 -4.830937969816759 3.440902862678898 1.047248237214836 1.3829324535162268 0.4513671487880615 0.10609227564683046 0.24393121941137175 4.780823210643089 0.026370407150910505 0.1992247545464874 1.4759173231615498e-05 4.830937969816759 0.3356842163013909 S(ph)SPSSSSTQPQEESR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPSSSSTQPQEESR 15 0 Q4G0A6 Q4G0A6 FAM188B Protein FAM188B 1 S(0.988)S(0.012)PSSSSTQPQEESR 178.22 1.5965999999999999e-28 0.0 1215.1 2161.4 2289.1 1138.1 3238.9 2176.5 2084.3 2003.2 3185.3 585.77 True False 1197.7724511779504 2156.3954110960217 2100.8990341815315 1221.799670590304 3048.394269922405 2083.416168669307 2192.214855441776 2096.275985041138 2826.537971303988 687.0195640105376 1.7434328131586931 3.1387685650578456 3.057990112999617 1.7784059357173763 4.437128765485415 3.0325427073825675 3.1909060094948787 3.05126097545744 4.114203029101271 1.0 9.42420737251403 -6.235362850992057 24.99595444136474 3.2376421097162065 2.525182394852651 0.10818727348866308 0.9551093389830442 1682.4762787067607 1612756.804442964 0.26548875664691807 0.3426388996176993 5.816170763895684e-07 6.235362850992057 -0.7124597148635554 S(ph)SPSTGSLDSGNESK ddPTM_PC-9_AZD4547_30min_R2 1 SSPSTGSLDSGNESK 15 0 A0A0U1RQT1;A0A087X1H5;Q15057 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 S(0.498)S(0.498)PS(0.004)TGSLDSGNESK 115.83 0.00015390000000000003 7343400.0 27788.0 31678.0 36598.0 42325.0 30988.0 34699.0 33764.0 34261.0 35149.0 43285.0 True False 36624.00597369385 41917.294002946786 36112.68660729159 32567.62516473145 26685.851091815475 32529.26604467877 36768.930590465025 28966.749689457705 37006.904381894296 41769.60532492864 0.876809959988685 1.0035357929975461 0.8645685379684224 0.7796967414794956 0.6388820503383836 0.7787783914076124 0.880279579000974 0.6934887094125827 0.8859768746679562 1.0 15.350165891293912 -5.5389954065656255 4.227524292502773 0.7909382028540947 0.9404874914902855 0.20028440963241245 0.10091253204131373 0.25534251087504894 10.745607394578428 0.0266986639782307 0.05169782457370404 2.890710456593588e-06 5.5389954065656255 0.14954928863619088 S(ph)SPSTGSLDSGNESK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPSTGSLDSGNESK 15 0 A0A0U1RQT1;A0A087X1H5;Q15057 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 S(0.494)S(0.494)PS(0.013)TGSLDSGNESK 94.53200000000001 0.0030144 6671300.0 31457.0 33582.0 28462.0 30113.0 35961.0 35588.0 30019.0 34756.0 36324.0 21453.0 True False 31008.4174114927 33504.24294227193 26121.964226497217 32327.61047402322 33845.84468204625 34065.984199679886 31573.23693590492 36370.89064301606 32232.80861132264 25161.12246567433 1.2323940417918737 1.3315877695035097 1.0381875555088491 1.2848238594333643 1.3451643394772994 1.3539135325204144 1.2548421470058904 1.4455193997260847 1.2810560679594383 1.0 14.618908663433595 -4.4449788360946725 13.002869980072216 1.2732873945039185 0.8112615141500322 0.0 0.13237117280719685 2331570.611123534 10910196.12536756 0.032229852829876414 28575092.51215202 3.5893942594469224e-05 4.4449788360946725 -0.46202588035388625 S(ph)SPSTGSLDSGNESKEK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPSTGSLDSGNESKEK 17 1 A0A0U1RQT1;A0A087X1H5;Q15057 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 S(0.549)S(0.152)PS(0.181)T(0.092)GS(0.026)LDS(0.001)GNESKEK 59.342 0.018484999999999998 5384000.0 42135.0 20569.0 19118.0 18721.0 22393.0 19228.0 11659.0 15692.0 18765.0 12702.0 True False 41534.14717338734 20521.3737442556 17546.19183761413 20097.804791425257 21075.887766331893 18405.663262657217 12262.645972074875 16421.107606462432 16651.488095789817 14897.523775648893 2.787989990744501 1.3775023321526298 1.17779250443585 1.3490701605240334 1.41472422422188 1.2354847382584908 0.8231331700989851 1.102270944739417 1.1177352925596875 1.0 13.86278492946674 -4.747554853855317 3.3217341561786236 1.1668466606902035 3.081397309552138 0.9038183066916415 0.15903529116079093 0.1159251133750111 1.882918582830798 0.04500836331262758 0.5999366985362411 1.7883196399330448e-05 4.747554853855317 1.9145506488619346 up S(ph)SPSVLIHSLGK ddPTM_PC-9_AZD4547_30min_R2 2 SSPSVLIHSLGK 12 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 S(0.625)S(0.375)PSVLIHSLGK;S(0.491)S(0.491)PS(0.017)VLIHSLGK 99.991 0.0017982 24984900.0 53388.0 52158.0 152305.0 180239.0 165643.0 172274.0 107590.0 212893.0 134100.0 135678.0 True False 70364.27346061489 69017.05349471858 150285.33618568073 138687.68321479112 142646.3286563052 161501.67954641284 117165.30157055224 179995.27864445682 141188.25222942396 130927.9545171693 0.5374274250300582 0.5271376441283057 1.1478475833514452 1.0592671651080001 1.0895024609706188 1.2335156395132885 0.894883770258457 1.3747658344486933 1.0783659818874598 1.0 16.998413635414067 -5.25993296195014 24.97938310173694 1.117370730041932 0.5322824711628436 0.7807923985123564 0.12234134228745482 50.94172623969686 844694.2186095495 0.029892815784458134 0.07093062273253714 5.4962570798175215e-06 5.25993296195014 -0.5850882588790884 S(ph)SPSVLIHSLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPSVLIHSLGK 12 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 S(0.49)S(0.49)PS(0.019)VLIHSLGK;S(0.487)S(0.487)PS(0.027)VLIHSLGK 104.7 0.0010653 25891000.0 86285.0 108607.0 219716.0 156673.0 221940.0 196086.0 181649.0 119710.0 153171.0 123105.0 True False 100891.34629356793 119388.78520134209 224954.86271756992 147895.11975071896 178452.45020962067 185802.90497032524 164441.89169512675 116567.73934322964 155410.83610393718 145422.962001356 0.6937786502562584 0.8209761619367156 1.5469005693576254 1.0169997757942786 1.2271270489453838 1.2776724006528812 1.1307835394907813 0.8015772594574349 1.068681547708319 1.0 17.14989556040677 -10.954154926275946 3.3769807147242425 0.9990911710988037 1.075750812285404 0.004725021876440305 0.24045445273538082 27910574.23667439 31104541.37607844 160343.82712470603 0.06033403772889974 1.111335208914099e-11 10.954154926275946 0.07665964118660029 S(ph)SPSVLIHSLGK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPSVLIHSLGK 12 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 S(0.499)S(0.499)PS(0.001)VLIHSLGK 95.854 0.0025311 9117600.0 34330.0 53603.0 90857.0 52667.0 85655.0 95742.0 67426.0 78634.0 107630.0 51787.0 True False 33840.447904649045 53478.885546858495 83387.08817816248 56540.30687196162 80616.94130420919 91647.3378455027 70916.98836204823 82287.62270753035 95507.57600585435 60738.313948159994 0.5571515852997135 0.8804802450147463 1.372891059329259 0.9308837074440136 1.3272831605601623 1.5088884081261045 1.1675824327717708 1.3547893801886342 1.5724436487876472 1.0 15.890319240435632 -4.643581406524605 0.9799529950625334 1.3146174418272247 4.5354511092132775e-18 0.5845495542902682 0.19574379534879138 1.723914812334869 1.1071220554005092 0.0638738308790938 2.5576171527112543 2.272053709223127e-05 4.643581406524605 -1.3146174418272247 S(ph)SPTPESR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPTPESR 8 0 K7EQ92;Q8NCA9 K7EQ92 ZNF784 Zinc finger protein 784 1 S(0.938)S(0.059)PT(0.003)PESR 96.03399999999999 0.006243899999999999 12422000.0 23091.0 24495.0 26361.0 21156.0 23257.0 18653.0 24263.0 28576.0 26497.0 18571.0 True False 22761.718105629214 24438.28333246831 24193.70033640266 22711.88281434713 21889.06898502126 17855.254672266743 25519.219420229216 29903.745281816864 23512.628834220228 21780.972605697953 1.0450276265291614 1.1220014723343987 1.110772267812941 1.0427396069726311 1.0049628811936078 0.8197638827017195 1.1716290122670339 1.3729297503452154 1.0795031636038728 1.0 14.410780757024293 -7.487362905601642 24.895934225603572 1.1901858574512645 1.0294863300983454 0.20760896286817654 0.11915753875707756 728.8742217631209 510928.37511516904 0.05039194723558919 0.033957024442019264 3.255645387308882e-08 7.487362905601642 -0.16069952735291904 S(ph)SPTQETQAPFIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPTQETQAPFIAK 14 0 O15231-5 O15231-5 ZNF185 Zinc finger protein 185 1 S(0.955)S(0.045)PTQETQAPFIAK;S(0.594)S(0.357)PT(0.045)QET(0.004)QAPFIAK 153.0 0.00025864 17789100.0 72673.0 78863.0 73938.0 87377.0 96686.0 87043.0 75058.0 72929.0 76207.0 75743.0 True False 84975.10354282305 86691.99745258996 75700.96233142639 82481.549970056 77741.07236625838 82478.31184955596 67947.96286713824 71014.69102466281 77321.38320552047 89474.606318742 0.9497119578275648 0.9689005743569372 0.8460608595666939 0.9218431168752605 0.8688618543826347 0.9218069264897057 0.7594105820938982 0.7936854259149455 0.8641712591623236 1.0 16.44919067045992 -5.157277241768036 0.7049192015174207 0.851786630809293 1.000759036946223 0.1553039511927694 0.06709116251787917 3.047648567350265 1.614669461837038 0.030621816818575415 0.3338920031911275 6.9618194863305255e-06 5.157277241768036 0.14897240613692997 S(ph)SPTQETQAPFIAK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPTQETQAPFIAK 14 0 O15231-5 O15231-5 ZNF185 Zinc finger protein 185 1 S(0.952)S(0.041)PT(0.005)QET(0.001)QAPFIAK 67.102 0.035095 14788000.0 40211.0 35900.0 43239.0 37680.0 40127.0 38738.0 37901.0 32833.0 44518.0 34245.0 True False 39637.58376620571 35816.87575568944 39684.05632736674 40451.11289679523 37766.80875271736 37081.26604268855 39863.328328982716 34358.54104275944 39503.914044677396 40164.20262140575 0.9868883527910653 0.8917611559055483 0.9880454169957028 1.007143432625663 0.9403101838897038 0.9232416834518674 0.9925088941697879 0.8554518402027943 0.9835602717436635 1.0 15.293622614571213 S(ph)SPTSASACGAQGLR ddPTM_PC-9_AZD4547_30min_R2 2 SSPTSASACGAQGLR 15 0 Q8IVL0-3;Q8IVL0-2;Q8IVL0;H0YHA8;A0A2R8YFX5 Q8IVL0-3 NAV3 Neuron navigator 3 1 S(0.982)S(0.018)PTSASACGAQGLR;S(0.584)S(0.311)PT(0.1)S(0.005)ASACGAQGLR 177.93 4.1658999999999995e-05 12284500.0 17673.300000000003 25341.0 26534.0 26337.0 33071.0 28430.0 28801.0 34483.0 23154.3 24147.0 True False 23293.041772523513 33531.98267973591 26182.1418229924 20265.41155259379 28479.6624970127 26652.267605700967 31364.233205070006 29154.444690510205 24378.189027559685 23301.620879774782 0.9996318235844822 1.43904077972708 1.1236189086621795 0.8696996512454485 1.222218087057297 1.1437945773478129 1.3460107932789074 1.2511766816966594 1.0462014275032403 1.0 14.508142692964599 -8.429432237978709 5.328263681988558 1.001313824866073 1.1772276643410213 0.13768505972487055 0.15322359887766962 0.41592973110142883 16.941569449345877 0.15037744685444307 0.03908611387155923 3.7202126230040797e-09 8.429432237978709 0.17591383947494843 S(ph)SPTSASACGAQGLR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPTSASACGAQGLR 15 0 Q8IVL0-3;Q8IVL0-2;Q8IVL0;H0YHA8;A0A2R8YFX5 Q8IVL0-3 NAV3 Neuron navigator 3 1 S(0.494)S(0.494)PT(0.01)S(0.002)ASACGAQGLR 155.14 0.00018763 5716700.0 11820.0 12313.0 14590.0 12224.0 16257.0 14603.0 11474.0 11506.0 16566.0 10782.0 True False 11651.444632477474 12284.49000500846 13390.466519028674 13122.993738068591 15300.79522249175 13978.463731255644 12068.067577286825 12040.610764718112 14700.162632286396 12645.654333888067 0.9213793390867651 0.971439648803957 1.0588986671211347 1.0377473076186607 1.2099646897265242 1.1053966336716865 0.9543252771781517 0.9521540322711062 1.1624675358152576 1.0 13.626354068969091 -5.098099733182089 2.3251686850515005 1.0618693437016753 0.9196464901950641 0.26023665365591186 0.07877498784002236 0.5209760272885438 4.938856850202492 0.02276886856377313 0.11321875712534892 7.978114535056925e-06 5.098099733182089 -0.14222285350661124 S(ph)SPVEFECINEK ddPTM_PC-9_AZD4547_30min_R2 2 SSPVEFECINEK 12 0 O75131;H0YB26 O75131 CPNE3 Copine-3 1 S(0.973)S(0.027)PVEFECINEK;S(0.68)S(0.32)PVEFECINEK 193.0 2.2655999999999998e-05 13600700.0 42091.0 51403.0 56800.0 61148.0 70984.0 70442.0 57648.0 75762.0 63907.0 58025.0 True False 55475.062452812286 68018.01450954829 56046.79488753929 47051.27332718243 61129.096873029186 66037.25060431878 62778.56032102621 64054.723737564396 67284.99355127368 55993.56241143545 0.9907400076670729 1.2147470455578142 1.0009506892187479 0.8402979074889732 1.0917165159783604 1.1793721949513276 1.1211746068188202 1.1439658592696118 1.2016558806683857 1.0 15.772973349380973 -6.514548428853526 24.85009877687058 1.1374852825117723 1.0179949467000238 0.23975289275597178 0.09818532608833792 558.4011284319668 1665767.6155949186 0.0327648792142322 0.03430057593856541 3.0580992140940023e-07 6.514548428853526 -0.1194903358117485 S(ph)SPVEFECINEK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPVEFECINEK 12 0 O75131;H0YB26 O75131 CPNE3 Copine-3 1 S(0.942)S(0.058)PVEFECINEK 162.32 0.0006744 8268000.0 25551.0 39547.0 35152.0 33066.0 33903.0 29504.0 36079.0 35356.0 32031.0 26216.0 True False 25186.638054520452 39455.431351260464 32261.938250643998 35497.78394494244 31908.89219586254 28242.182697183212 37946.994084097205 36998.76883342376 28423.331478616754 30747.400669375795 0.8191469036797694 1.283211929864296 1.0492574184580317 1.1544970687651654 1.0377752753468876 0.9185226094676757 1.234152912375847 1.2033137119871824 0.9244141247662019 1.0 14.908176832280754 -10.853897033049865 14.656866412207867 0.9999999999873662 1.0809884350117134 0.014818985730014611 0.14389807949677913 0.0 0.0 0.13249052846890313 0.03213367289418497 1.3999191903008243e-11 10.853897033049865 0.08098843502434716 S(ph)SPVESLKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPVESLKK 9 1 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2;B1AKL5 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 S(0.923)S(0.077)PVESLKK 77.37899999999999 0.033999 10380000.0 54792.0 66235.0 60150.0 65097.0 68418.0 66576.0 73237.0 54835.0 57322.0 50100.0 True False 64067.203408671056 72810.37306813482 61584.204120145296 61449.82613732154 55011.98404272255 63084.637359650245 66299.46117003658 53395.63935248506 58160.225807430244 59182.73340861822 1.082532010921644 1.2302637758453403 1.0405772186111526 1.0383066580086884 0.929527598242221 1.0659297691455363 1.120250068753702 0.9022165127761664 0.9827228730020253 1.0 15.852888709808731 -5.429958344494791 5.239445194349785 1.0077600431399891 1.155553844661381 0.4339377400607527 0.0677919859893444 0.20274941516384082 8.74172352943934 0.018247243078439217 0.038744706379798155 3.7157086673604655e-06 5.429958344494791 0.14779380152139177 S(ph)SPVGGGPR ddPTM_PC-9_AZD4547_30min_R2 1 SSPVGGGPR 9 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 S(0.5)S(0.5)PVGGGPR 110.53 0.0022954 78388000.0 32346.0 28685.0 48690.0 56183.0 45378.0 44748.0 41224.0 59326.0 44872.0 47545.0 True False 42631.35516140423 37956.86528425178 48044.33878651915 43230.87736869714 39078.047981296055 41949.900486102895 44892.85613853013 50158.52987585793 47243.8423119964 45880.46402157169 0.9291831735040904 0.8272990714829199 1.0471633147374024 0.9422502211043726 0.8517361106662449 0.9143303447493304 0.9784743266202098 1.0932437355532152 1.029715878413603 1.0 15.485592361971955 -7.512557689988317 4.043862991997401 1.0460013435672155 0.9193427360371186 0.46256281553288103 0.05902080606683034 0.19167918030788192 7.245352590540974 0.02879265767680696 0.017172772091746332 3.072149245815258e-08 7.512557689988317 -0.12665860753009694 S(ph)SPVGGGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPVGGGPR 9 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 S(0.5)S(0.5)PVGGGPR;S(0.633)S(0.367)PVGGGPR 136.52 0.00099731 29858000.0 63233.0 92201.0 110298.0 85329.0 119141.0 97706.0 105084.0 100077.0 92993.0 79869.0 True False 73937.09799132177 101354.10594481908 112927.92262749448 80548.29277035038 95796.1763108247 92582.12535841731 95129.6827777234 97450.08479034634 94352.8466995285 94348.61745734407 0.7836585207488542 1.0742510984926967 1.1969218592794992 0.8537305043899245 1.0153426610001475 0.9812769688996725 1.0082785030817485 1.0328724195074133 1.000044825693247 1.0 16.52571375691892 -7.502233774801968 19.91709326360253 1.0139902326319365 0.9935560682294827 0.009546609781151516 0.10623072601187354 519.4273147887369 501131.0073671476 0.0456611110579362 0.030190750662303176 3.1460543800263655e-08 7.502233774801968 -0.020434164402453825 S(ph)SPVGGGPR ddPTM_PC-9_Lapatinib_30min_R1 2 SSPVGGGPR 9 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 S(0.5)S(0.5)PVGGGPR;S(0.659)S(0.341)PVGGGPR 139.38 0.00083461 140604000.0 50858.0 62713.0 57432.0 55972.0 64262.0 59442.0 56318.0 50351.0 51523.0 37872.0 True False 50132.755593785056 62567.791901575256 52710.16265393114 60088.367597118406 60482.23550395303 56899.8042260698 59233.870473909636 52690.49127536256 45719.93717875719 44418.12473873203 1.1286553831046797 1.4086094869965762 1.1866814045836689 1.3527893838508254 1.361656662898542 1.2810041972900739 1.3335518062125316 1.186238536302212 1.0293081359846332 1.0 15.438860865472607 -8.126441863407884 2.467237864049965 1.0025896777851162 1.2980233378669523 0.6597096238343703 0.07929548693113958 0.16635870924573234 1.8141195031044008 0.06408063284016723 0.020021103489531487 7.474086789469136e-09 8.126441863407884 0.29543366008183614 S(ph)SPVKVGEK ddPTM_PC-9_AZD4547_30min_R2 1 SSPVKVGEK 9 1 P49916-4;P49916-3;P49916-2;P49916 P49916-4 LIG3 DNA ligase 3 1 S(0.912)S(0.088)PVKVGEK 121.68 0.0077323999999999995 8536000.0 24347.0 17902.0 25857.0 36752.0 35819.0 32149.0 23683.0 28744.0 24936.0 30878.0 True False 32088.8395509401 23688.4714073096 25514.11928533634 28279.39421273976 30846.15013094549 30138.717947790356 25790.741119949762 24302.275271409842 26254.066052147038 29796.970618531745 1.0769161725112741 0.7949959648776154 0.8562655449768523 0.9490694398024425 1.0352109456308698 1.0114691971084493 0.8655491006159407 0.8155955040709888 0.881098497839198 1.0 14.862878042593225 -10.711965841863847 5.034622236878245 1.0000068407235858 0.9172549058641881 0.0632545306605573 0.09070623216318129 7.3172949057155225e-06 1.178517219312412e-06 0.09227116600917704 0.022377195127739117 1.9410385381816018e-11 10.711965841863847 -0.08275193485939769 S(ph)SPVLQHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SSPVLQHK 8 0 A0A2R8Y4C6;A0A2R8YCU9;A0A2U3TZV9;A0A2R8Y7B1;H7C2C6;A0A2R8Y820;A0A2R8Y4Z5;A0A2R8Y885;A0A2R8Y7D4;A0A2R8YDS8;H0Y470;H0Y7U8;A0A2R8Y5D7;H0Y7K3;Q3V6T2-5;Q3V6T2-4;Q3V6T2-2;Q3V6T2-3;Q3V6T2 A0A2R8Y4C6 CCDC88A Girdin 1 S(0.5)S(0.5)PVLQHK;S(0.5)S(0.5)PVLQHK;S(0.5)S(0.5)PVLQHK;S(0.78)S(0.22)PVLQHK;S(0.5)S(0.5)PVLQHK 120.45 0.0019355 28135400.0 114148.0 130396.0 146478.0 169037.0 205382.0 167606.0 175607.0 161026.0 169519.0 144021.0 True False 133471.001874233 143340.8531228575 149970.5910409081 159566.40491534784 165138.87144702338 158816.4463065001 158972.23367541833 156799.23812114965 171997.8946765601 170130.8672303916 0.7845196115616474 0.842532901032856 0.8815013611716773 0.9379039060517024 0.9706579066771697 0.9334957782318861 0.9344114696137873 0.9216389751826268 1.0109740664734295 1.0 17.37628539063033 -3.1132707347731503 0.43935694414771903 0.9697037732121122 1.2272520043495148e-16 0.8409606950714814 0.026381790550505792 8.256295037097999 0.38613170009934816 0.018186356030478797 5.70357433263118 0.0007704230454254876 3.1132707347731503 -0.9697037732121121 S(ph)SPVLQHK ddPTM_PC-9_Lapatinib_30min_R1 3 SSPVLQHK 8 0 A0A2R8Y4C6;A0A2R8YCU9;A0A2U3TZV9;A0A2R8Y7B1;H7C2C6;A0A2R8Y820;A0A2R8Y4Z5;A0A2R8Y885;A0A2R8Y7D4;A0A2R8YDS8;H0Y470;H0Y7U8;A0A2R8Y5D7;H0Y7K3;Q3V6T2-5;Q3V6T2-4;Q3V6T2-2;Q3V6T2-3;Q3V6T2 A0A2R8Y4C6 CCDC88A Girdin 1 S(0.5)S(0.5)PVLQHK;S(0.5)S(0.5)PVLQHK;S(0.5)S(0.5)PVLQHK 104.42 0.0021866 32329400.0 154689.0 159896.0 160056.0 135298.0 159917.0 146598.0 141890.0 146559.0 165683.0 118235.0 True False 152483.10649351173 159525.7706359811 146896.813514027 145248.2662608974 150510.9964689188 140328.34527662888 149236.36992689795 153368.66617993385 147022.035820663 138671.76221176577 1.0995973806163553 1.15038395771137 1.0593130942527487 1.047424969180738 1.085375955914322 1.0119460735079817 1.0761842753465478 1.1059833936899455 1.0602161065505573 1.0 17.081314515417937 -1.522879599429621 0.009559529855885858 0.00016375181528485217 2.2775531598670113 0.36334694973598625 0.033753947749809006 17185.166324037367 12.74571345291961 1317.2317875642123 1747.296052097532 0.02999994099751581 1.522879599429621 2.2773894080517265 S(ph)SPVNRPSSATNK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPVNRPSSATNK 13 1 Q96L91-5;Q96L91-2;Q96L91;Q96L91-4;Q96L91-3;A0A0A0MR80;A0A0A0MR72 Q96L91-5 EP400 E1A-binding protein p400 1 S(0.499)S(0.499)PVNRPSSATNK 60.196000000000005 0.027548000000000003 18416000.0 14826.0 16386.0 16184.0 13680.0 14155.0 17567.0 14127.0 12611.0 14841.0 10289.0 True False 14614.578521244584 16348.059223752833 14853.413992046622 14686.072835142222 13322.430729800737 16815.700360677096 14858.426936058127 13196.95309871895 13169.450297341686 12067.43994076927 1.211075306193978 1.3547247223929986 1.230867032688936 1.216999869667967 1.1039980969610248 1.393477029362794 1.231282443416987 1.0936000645947839 1.091320972963729 1.0 13.55883202610657 -7.797422847542941 3.554474480770528 1.0595042019635632 1.2523822367997568 0.554090306831085 0.07774131966044882 0.18601216112650107 4.84011688464775 0.04650990881615545 0.02157734665386126 1.5943260877405483e-08 7.797422847542941 0.1928780348361936 S(ph)SPVPPVPER ddPTM_PC-9_AZD4547_30min_R2 3 SSPVPPVPER 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 S(0.926)S(0.074)PVPPVPER;S(0.928)S(0.072)PVPPVPER;S(0.991)S(0.009)PVPPVPER 141.1 0.00011544 549530000.0 356831.0 327020.0 451140.0 545350.0 484950.0 446000.0 380137.0 512490.0 389903.0 426584.0 True False 470295.83545412315 432722.8197753534 445157.588830361 419627.9830735099 417623.06334632443 418111.5494949915 413968.4565770526 433296.4463486239 410512.47657724953 411649.42400206387 1.1424668857347053 1.0511925792787795 1.081399761239868 1.0193819269656164 1.0145114726171234 1.0156981283493676 1.0056335134698915 1.0525860625191874 0.9972380687096294 1.0 18.651056681843677 -1.522878745342517 0.5654106460654091 1.013991583696089 7.087762786528838 0.7721512393049849 0.020659570365913694 66.67342007545919 0.5810536202186394 0.00960949697561546 494.6420913535737 0.029999999995704796 1.522878745342517 6.073771202832749 S(ph)SPVPPVPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SSPVPPVPER 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 S(0.915)S(0.085)PVPPVPER;S(0.812)S(0.188)PVPPVPER;S(0.992)S(0.008)PVPPVPER;S(0.994)S(0.006)PVPPVPER;S(0.993)S(0.007)PVPPVPER;S(0.995)S(0.005)PVPPVPER 157.97 0.00011882 618829700.0 688700.0 745488.0 808716.0 834173.0 896650.0 742240.0 790521.0 787803.0 656044.0 558664.0 True False 805283.3075549685 819495.1218814463 827998.8565125077 787436.9912353561 720957.8691558805 703315.627761157 715637.1280035852 767124.005996276 665637.4023866904 659945.3608182095 1.2202272420804157 1.2417620768868272 1.2546475900458534 1.1931851301433207 1.0924508481460145 1.0657179662406846 1.084388451668678 1.1624053316250076 1.008625019443161 1.0 19.331987058090135 -6.184304179407019 2.6459207167205587 1.0753984970248034 1.2386970285909318 0.7681152279770995 0.04318106641807759 0.1374879204800005 1.8865748275897578 0.013461984236714034 0.017910562737564095 6.541778280976725e-07 6.184304179407019 0.1632985315661284 S(ph)SPVPPVPER ddPTM_PC-9_Lapatinib_30min_R1 4 SSPVPPVPER 10 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 S(0.987)S(0.013)PVPPVPER;S(0.873)S(0.127)PVPPVPER;S(0.918)S(0.082)PVPPVPER;S(0.997)S(0.003)PVPPVPER 166.86 0.00011411 609090000.0 555220.0 509062.0 626380.0 516090.0 543060.0 524872.0 445018.0 465642.0 577080.0 477480.0 True False 547302.4609851232 507883.29821567546 574881.4542967225 554044.9802257715 511118.27849703975 502424.4480963911 468058.85455020337 487277.4272296939 512083.1734781975 560011.7817978936 0.9773052617358019 0.9069153805749195 1.026552427970516 0.989345221357726 0.9126920095432932 0.8971676390153421 0.8358017987541632 0.8701199565218268 0.914415000045493 1.0 19.095097654040252 -6.404343543887586 3.967805515223922 0.8921967535146826 0.9735517484402035 0.3221733134598356 0.04835971456857049 0.25529476638089393 6.95427389915523 0.015478889021082179 0.017549598720094657 3.9414539433381795e-07 6.404343543887586 0.0813549949255209 S(ph)SPVPVSDTQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPVPVSDTQK 11 0 Q76FK4-2;Q76FK4-4;Q76FK4;F8WE42;F5H101;F5GWN9 Q76FK4-2 NOL8 Nucleolar protein 8 1 S(0.623)S(0.375)PVPVS(0.001)DTQK 67.385 0.039837 5088500.0 14231.0 28495.0 16570.0 17082.0 22055.0 15143.0 21907.0 13619.0 11510.0 13828.0 True False 16640.027224937916 31323.795283105574 16965.091642074934 16124.950920591222 17733.48107314222 14348.874422272045 19831.810367054808 13261.515680523273 11678.311975219334 16334.906937612237 1.01867903432147 1.9175986372460072 1.038579020184783 0.9871467882968114 1.0856187391132097 0.8784178861302714 1.2140755036314723 0.811851315172646 0.7149298137921573 1.0 13.995670615101197 -5.488220358780581 22.192928977823275 0.9650694992580994 1.4706274624809037 0.41487005662438314 0.23996634035920333 135.3205270300698 86648.89819956695 0.05900182830534402 0.12264165335668142 3.2492239160683493e-06 5.488220358780581 0.5055579632228043 S(ph)SPVTVNQTDKEK ddPTM_PC-9_AZD4547_30min_R2 1 SSPVTVNQTDKEK 13 1 Q8IVL0-3;Q8IVL0-2;Q8IVL0;H0YHA8;A0A2R8YFX5 Q8IVL0-3 NAV3 Neuron navigator 3 1 S(0.445)S(0.445)PVT(0.102)VNQT(0.008)DKEK 67.646 0.016349000000000002 18546000.0 55016.0 50862.0 60380.0 47113.0 55137.0 62961.0 60050.0 59102.0 59808.0 56806.0 True False 72509.94359611142 67302.14683937989 59579.32174840882 36251.825738594045 47482.17928389795 59024.038716937626 65394.33366773559 49969.14392885001 62969.328779548065 54817.23923040071 1.322758034043762 1.2277551329519576 1.0868719874416286 0.6613216252322572 0.8661906354737606 1.0767422720588946 1.1929519725150441 0.9115589298254548 1.1487139750851654 1.0 15.742342050856056 -5.305708348713202 3.377762473943466 0.9788603680617437 1.2877434061655892 0.39189351668279826 0.144794970584623 0.252724954848445 5.852223454246191 0.041840531470621334 0.1081163114555033 4.946427537580645e-06 5.305708348713202 0.30888303810384554 S(ph)SPVTVNQTDKEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPVTVNQTDKEK 13 1 Q8IVL0-3;Q8IVL0-2;Q8IVL0;H0YHA8;A0A2R8YFX5 Q8IVL0-3 NAV3 Neuron navigator 3 1 S(0.499)S(0.499)PVT(0.001)VNQTDKEK 68.173 0.037337999999999996 0.0 15413.0 17427.0 15282.0 15196.0 17218.0 11698.0 17719.0 18537.0 14263.0 12479.0 True False 18022.116479373755 19157.03738896932 15646.380837307735 14344.617386096721 13844.256500447189 11084.536286847946 16040.528045549105 18050.423391575016 14471.56939205502 14741.343916290356 1.2225558661213978 1.2995448378216907 1.0613944648572537 0.9730874923991685 0.9391448011160085 0.7519352611127031 1.0881320004903383 1.224476105711628 0.9816994620187096 1.0 13.847580435392555 -5.384999782002938 3.879646434541285 0.9960510772410535 1.260628351698684 0.46250527876013237 0.11312945597000443 0.22165551761242874 5.749622588289683 0.03366134502910135 0.0761508675746141 4.120977259525284e-06 5.384999782002938 0.2645772744576306 S(ph)SPVVNDGVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPVVNDGVVR 11 0 H0Y8R1;F5H5I6;H0YAK1;Q12849-5;Q12849;H0YAM1 H0Y8R1 GRSF1 G-rich sequence factor 1 1 S(0.887)S(0.113)PVVNDGVVR 101.72 0.003617 4974600.0 19753.0 18826.0 20907.0 21301.0 21614.0 19026.0 21344.0 18971.0 19561.0 13735.0 True False 23096.792760466487 20694.920863300405 21405.502170239033 20107.574028773757 17378.89185739724 18028.243066641226 19322.14180282184 18473.031351436006 19847.042619223743 16225.046773799813 1.4235270370846118 1.275492215943472 1.3192875477440604 1.239292207233784 1.0711150543775723 1.111136585180957 1.190883580935077 1.1385502679268842 1.2232348476968784 1.0 13.985935016802015 -5.960160768922304 2.899282370516466 1.1324834721898416 1.3349067133287125 0.6737348967159719 0.06766645009071742 0.16249810968286907 2.785674278593211 0.019957616836909848 0.030554911327576734 1.0960723724421357e-06 5.960160768922304 0.2024232411388709 S(ph)SPYGR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPYGR 6 0 P79522-2;P79522 P79522-2 PRR3 Proline-rich protein 3 1 S(0.999)S(0.001)PYGR 96.19 0.034612000000000004 12964000.0 8014.6 8159.5 8247.1 8557.6 10753.0 8962.6 8640.6 8908.0 9374.5 8677.9 True False 7900.310334302364 8140.607179068181 7569.055272726622 9186.954451316744 10120.5296812114 8579.290490841042 9087.9679892195 9321.89820025282 8318.645092138644 10177.863452425085 0.7762248306072482 0.7998345838613619 0.7436782098823638 0.902640764857949 0.9943668166229893 0.8429362931565809 0.8929151026342473 0.91589931853838 0.8173272446641595 1.0 13.313147120717753 -5.77122017540597 24.934520224049134 0.9060156135756864 0.775904747461535 0.5612063767189839 0.05511408252941783 139.8701949469762 356576.24884655955 0.015131548788061404 0.02276014984604694 1.693479035298025e-06 5.77122017540597 -0.13011086611415135 S(ph)SPYGTLKPEEMSGPGLAEPK ddPTM_PC-9_AZD4547_30min_R2 2 SSPYGTLKPEEMSGPGLAEPK 21 1 Q5JSZ5;A0A494C0D3;Q5JSZ5-5;A0A494C065;H0Y412 Q5JSZ5 PRRC2B Protein PRRC2B 1 S(0.391)S(0.391)PY(0.202)GT(0.015)LKPEEMSGPGLAEPK;S(0.366)S(0.366)PY(0.185)GT(0.082)LKPEEMSGPGLAEPK 67.13600000000001 0.011983 36079000.0 121018.0 107769.0 111759.0 148161.0 139154.0 135484.0 108858.0 109866.0 131444.0 126464.0 True False 159499.2066692274 142603.22171234209 110277.00263796658 114004.77051463145 119834.869072883 127012.16406228609 118546.15111411108 92888.73416952124 138391.86149175544 122036.5338526455 1.3069791613535717 1.1685289413785718 0.9036392558569541 0.9341855829196846 0.981958969906332 1.0407716447899813 0.9713988702534855 0.7611551331151446 1.134019929301322 1.0 16.89695358384644 -5.059538322073149 3.3712314247102033 0.9601314974538145 1.2928007006033357 0.6005404051712344 0.09158150999860173 0.15230243154182074 3.3088860143368493 0.023226261414618622 0.08967977398836667 8.718899624667159e-06 5.059538322073149 0.3326692031495212 S(ph)SPYGTLKPEEMSGPGLAEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPYGTLKPEEMSGPGLAEPK 21 1 Q5JSZ5;A0A494C0D3;Q5JSZ5-5;A0A494C065;H0Y412 Q5JSZ5 PRRC2B Protein PRRC2B 1 S(0.469)S(0.469)PY(0.061)GT(0.001)LKPEEMSGPGLAEPK 57.496 0.021724 20276000.0 56518.0 66587.0 62630.0 81899.0 99759.0 76974.0 96713.0 88598.0 75573.0 61282.0 True False 66085.38111861711 73197.31730184767 64123.33672559768 77310.4645501404 80211.94007597354 72937.34793501746 87551.64449851504 86272.39637734044 76678.11215493042 72391.94149195486 0.9128831159468404 1.0111252135706612 0.8857800385519969 1.0679429637721782 1.1080230537108573 1.0075340767469707 1.209411471693226 1.191740331856249 1.0592078424012417 1.0 16.143541488230056 -5.89997146541052 5.3475980332285635 1.1052704551997299 0.9449848736711983 0.5014058040961082 0.0708384654996788 0.16994775333648446 7.530469915117047 0.020366877602196885 0.030685170301177428 1.2590081300912263e-06 5.89997146541052 -0.16028558152853156 S(ph)SPYHSQLDVR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPYHSQLDVR 11 0 O94929 O94929 ABLIM3 Actin-binding LIM protein 3 1 S(0.949)S(0.05)PY(0.001)HSQLDVR 74.237 0.02306 3544600.0 19120.0 49038.0 57282.0 61005.0 64239.0 59387.0 52692.0 58428.0 60042.0 54039.0 True False 18847.345293821432 48924.455523885736 52572.495074914375 65491.51120671421 60460.588318733295 56847.15644785855 55420.13393606391 61142.77818190076 53279.43768971021 63379.56914755867 0.29737256891004626 0.7719278654290168 0.8294864698830068 1.0333221271075317 0.9539444513731313 0.8969318853447626 0.8744163881429391 0.9647080124440374 0.8406405787591645 1.0 15.951730231904603 -4.688745542030543 1.7973227944163164 0.9276269175047396 3.6212507243790396e-18 0.9043689369485896 0.061439776675051364 0.3199517516873503 0.8788091210365773 0.016706863357012252 0.5479739734994263 2.047644022741158e-05 4.688745542030543 -0.9276269175047396 down S(ph)SQGSSSSTQSAPSETASASK ddPTM_PC-9_Lapatinib_30min_R1 1 SSQGSSSSTQSAPSETASASK 21 0 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;A0A087WYS3;Q9ULU4-4;Q9ULU4-18;Q9ULU4-8;Q9ULU4-15;Q9ULU4-17;Q9ULU4-2 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 S(0.833)S(0.159)QGS(0.007)S(0.002)SSTQSAPSETASASK 263.26 9.299199999999998e-165 0.0 3377.7 4569.7 5206.7 3017.4 3120.8 4831.6 3940.4 2760.4 3744.0 2977.2 True False 3329.5333786056804 4559.11914041153 4778.6252244432235 3239.3096617513256 2937.2406797288695 4624.963731009705 4144.414631474727 2888.6582613356413 3322.311293932165 3491.8050531303606 0.9535278539163561 1.305662564502086 1.36852577727936 0.9276891500134935 0.8411811756488722 1.3245194564523244 1.1868974837983322 0.8272679079681137 0.9514595584177168 1.0 11.769757300464217 -7.755439560723848 24.998486338689407 0.9170227892113056 1.1342918780433586 0.2235439159473802 0.17337492004291938 215.62385648050417 898416.6322421879 0.08927850033526497 0.04982168103813561 1.7561452739192613e-08 7.755439560723848 0.21726908883205298 S(ph)SQPLASK ddPTM_PC-9_AZD4547_30min_R2 1 SSQPLASK 8 0 P17096;P17096-3;A0A669KAX1;A0A1W2PRV2;P17096-2 P17096;P17096-2 HMGA1 High mobility group protein HMG-I/HMG-Y 1 S(0.975)S(0.025)QPLASK 91.469 0.008701500000000001 6113400.0 36325.0 44821.0 41426.0 41913.0 51338.0 49081.0 40621.0 40542.0 49363.0 43642.0 True False 47875.59439306282 59308.511727573605 40876.66417273244 32250.6053993949 44210.60485838464 46011.95731112938 44236.19030669587 34277.16546247904 51972.22740343817 42114.106863590976 1.1368065942401082 1.408281360914904 0.9706169076583612 0.7657910330107607 1.0497813713961521 1.0925545081642993 1.0503888981898248 0.8139117273341198 1.2340811968725345 1.0 15.362015949970576 -5.2768030761846 24.831775859153705 0.9894215744404385 1.2725439737233881 0.38148531738586144 0.13999435331602364 622.6340561287697 1006340.1702356678 0.035924644281975504 0.07522345913462065 5.2868492106884924e-06 5.2768030761846 0.2831223992829496 S(ph)SQPLASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSQPLASK 8 0 P17096;P17096-3;A0A669KAX1;A0A1W2PRV2;P17096-2 P17096;P17096-2 HMGA1 High mobility group protein HMG-I/HMG-Y 1 S(0.913)S(0.087)QPLASK;S(0.974)S(0.026)QPLASK 82.417 0.016499 29411700.0 100563.0 153696.0 117896.0 103269.0 151640.0 99191.0 114633.0 96554.0 90952.0 89496.0 True False 117586.32969021345 168953.92313852266 120707.08776307003 97483.17273261526 121927.23055684811 93989.24934422412 103774.13236895016 94019.55980741922 92282.00093572102 105720.91635005361 1.1122333569345175 1.5981125492622255 1.1417521899204464 0.9220802855116932 1.1532933573251825 0.8890317317437484 0.9815856308447286 0.8893184343589124 0.8728830975146408 1.0 16.689901309333592 -5.517909064561394 5.262072809995932 0.9631870293201147 1.3617404192323002 0.5870649587220411 0.13320105408163746 0.10427733016868758 9.103786965136068 0.03416938536840106 0.06609215687206312 3.034526506821377e-06 5.517909064561394 0.3985533899121855 S(ph)SQPLASK ddPTM_PC-9_Lapatinib_30min_R1 3 SSQPLASK 8 0 P17096;P17096-3;A0A669KAX1;A0A1W2PRV2;P17096-2 P17096;P17096-2 HMGA1 High mobility group protein HMG-I/HMG-Y 1 S(0.949)S(0.051)QPLASK;S(0.989)S(0.011)QPLASK;S(0.946)S(0.054)QPLASK 80.979 0.018532 28284600.0 111862.0 130761.0 114074.0 102187.0 121775.0 101183.0 122477.0 129205.0 131647.0 110870.0 True False 110266.82736702164 130458.23093843205 104695.27605837422 109702.17286583893 114612.43391886164 96855.63895909321 128818.25977543643 135208.3359860427 116819.52855563248 130033.73177501134 0.8479863329448158 1.00326453111532 0.8051393636808135 0.843643963519014 0.8814054042313256 0.7448501064837241 0.9906526407957131 1.0397943221377712 0.8983786511469 1.0 16.988526392705808 -7.308077635357841 24.92616898349243 0.9855226818979905 0.8596509897456154 0.4461614319156385 0.06958201036296417 397.8007872942642 212606.13175053883 0.029111100726358703 0.019626759215188593 4.9195158556259165e-08 7.308077635357841 -0.12587169215237515 S(ph)SQPSPTAVPASDS(ph)PPTKQEVK ddPTM_PC-9_Lapatinib_30min_R1 1 SSQPSPTAVPASDSPPTKQEVK 22 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 2 S(0.342)S(0.349)QPS(0.259)PT(0.052)AVPAS(0.421)DS(0.557)PPT(0.022)KQEVK 58.672 0.030361000000000003 8596400.0 46165.0 42637.0 45501.0 34329.0 41659.0 44116.0 36374.0 38596.0 46977.0 29705.0 True False 45506.67863437584 42538.27664610947 41760.08341893924 36853.669178186945 39208.69952474527 42229.26151941884 38257.2677406511 40389.31106162526 41685.955570259444 34839.46967057551 1.3061817262049076 1.2209794537152834 1.198642913161468 1.0578137246822839 1.1254103433686848 1.2121097685675897 1.0981013230796153 1.1592975278764646 1.1965152157716767 1.0 15.088435042824518 -5.098927051404934 1.6887868557495178 1.1319969301050825 1.3115234223911199 0.46782741956749496 0.061744384744274634 0.49774213130402156 2.1379823965953917 0.017159563804983027 0.11900727315181922 7.962930928121798e-06 5.098927051404934 0.17952649228603734 S(ph)SQPSPTAVPASDSPPTK ddPTM_PC-9_AZD4547_30min_R2 1 SSQPSPTAVPASDSPPTK 18 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.448)S(0.448)QPS(0.081)PT(0.022)AVPASDSPPTK 205.0 5.334799999999999e-67 0.0 15593.0 15739.0 11294.0 17968.0 14407.0 14357.0 11606.0 17095.0 15116.0 13242.0 True False 20551.249645451553 20826.323957079978 11144.234180631498 13825.75520283271 12406.836732921958 13459.25452040269 12638.911516198823 14453.360554020004 15915.000900074368 12778.401610551107 1.608280148941509 1.6298066528041906 0.8721148794877225 1.0819628013113005 0.9709224291931513 1.0532815394759079 0.9890839168619409 1.1310773439837645 1.2454610040533847 1.0 13.641419767262535 -5.251358211155858 24.9984762415876 1.0449299921347392 1.6190435008032054 0.8553462037418172 0.09475580989880326 235.73681696856977 584558.511794363 0.024561027123038707 0.06337837641768651 5.605854079077603e-06 5.251358211155858 0.5741135086684661 S(ph)SQPSPTAVPASDSPPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSQPSPTAVPASDSPPTK 18 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.684)S(0.313)QPS(0.003)PTAVPASDSPPTK 182.47 3.1279e-33 0.0 7201.5 11380.0 10390.0 9247.7 9869.4 8053.5 9670.9 7164.9 6379.1 5999.6 True False 8420.571713891528 12509.731192200074 10637.73700429442 8729.581350447921 7935.5619180807 7631.160282623514 8754.802340747268 6976.828966839067 6472.382269428467 7087.279987192533 1.1881246019782477 1.7650962308257168 1.500961867390302 1.231725198697272 1.1196907604075332 1.076740342756859 1.2352838263153318 0.9844155980075484 0.9132392513241679 1.0 12.791016329346517 -5.954211612815028 2.348867059663817 1.062746474563898 1.5166823163970329 0.6083817445167843 0.1536234396960492 0.19319905825021905 2.1550518207804985 0.04731734839476813 0.07531158509270973 1.1111901607079884e-06 5.954211612815028 0.45393584183313496 S(ph)SQPSPTAVPASDSPPTK ddPTM_PC-9_Lapatinib_30min_R1 1 SSQPSPTAVPASDSPPTK 18 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.948)S(0.052)QPSPTAVPASDSPPTK 235.54 4.949599999999999e-113 0.0 14164.0 20907.0 25443.0 19458.0 25518.0 25907.0 22005.0 20872.0 20361.0 21242.0 True False 13962.018762640519 20858.59112602225 23351.17475282019 20889.006229985167 24017.081410318293 24799.01800216665 23144.311228708088 21841.78931698213 18067.72976916475 24913.651396814173 0.5604163974304428 0.8372354093663499 0.9372843177779318 0.838456230171718 0.9640129031182266 0.9953987718290791 0.9289810979561053 0.8766996442671242 0.7252140395395898 1.0 14.604648861024769 -4.7635084670481 2.9435070206824103 0.906984197392172 0.4927321698020724 0.6439033384148797 0.07740500260280578 0.27291425415069825 3.2485772769763166 0.020273185488926787 0.27791995790073337 1.7238184829640027e-05 4.7635084670481 -0.41425202759009955 S(ph)SRGQEEISGALPVASPASSR ddPTM_PC-9_AZD4547_30min_R2 2 SSRGQEEISGALPVASPASSR 21 1 H0Y9D5;H0Y8S9;Q9UBK8;Q9UBK8-1 H0Y9D5 MTRR Methionine synthase reductase 1 S(0.499)S(0.499)RGQEEIS(0.002)GALPVASPASSR;S(0.5)S(0.5)RGQEEISGALPVASPASSR 99.87299999999999 0.00010206 71953000.0 41145.0 23023.0 44174.0 81146.0 67466.0 50712.0 46912.0 48951.0 32465.0 49376.0 True False 54228.254130834655 30464.7345106965 43588.223897221134 62439.0433932025 58099.51044792901 47540.97062329605 51087.07711941401 41386.747732075666 34181.033621388924 47647.361268884706 1.1381166277983896 0.6393792583555088 0.9148087687635638 1.3104407406917042 1.2193647014377247 0.9977671240808432 1.072191108991707 0.8686052412959661 0.7173751643558541 1.0 15.5401086988325 -7.823261753803224 5.875532594475468 0.8399050184431167 1.0367586209092796 0.16583855508702183 0.18306313430155458 0.38779696452798545 25.81229828108206 0.10994682195110571 0.0524500619554592 1.502236279747068e-08 7.823261753803224 0.1968536024661629 S(ph)SRGQEEISGALPVASPASSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSRGQEEISGALPVASPASSR 21 1 H0Y9D5;H0Y8S9;Q9UBK8;Q9UBK8-1 H0Y9D5 MTRR Methionine synthase reductase 1 S(0.499)S(0.499)RGQEEIS(0.002)GALPVASPASSR;S(0.5)S(0.5)RGQEEISGALPVASPASSR;S(0.5)S(0.5)RGQEEISGALPVASPASSR;S(0.497)S(0.497)RGQEEIS(0.007)GALPVASPASSR 96.41 0.00015073 54675700.0 46615.9 47360.2 54355.4 73264.0 69818.0 78474.0 89801.0 86645.0 88018.0 62458.1 True False 54507.051164006974 52061.80766334218 55651.43888000242 69159.25560509291 56137.664092706545 74358.68529441829 81294.39917706163 84370.66055796621 89305.09673630365 73781.25911195237 0.7387655323325456 0.7056237354847242 0.7542760797231641 0.9373553181052896 0.7608661707375551 1.0078261904095422 1.1018299247741103 1.14352427125086 1.210403533515145 1.0 16.17096678906293 -6.887660993249668 1.2962947464403483 1.1415140034252196 0.7613901102504198 0.80012323925892 0.07881606364193855 0.18307776010057797 0.639066853681211 0.04070715677870517 0.032733015840209476 1.2952064746222683e-07 6.887660993249668 -0.3801238931747998 S(ph)SRGQEEISGALPVASPASSR ddPTM_PC-9_Lapatinib_30min_R1 3 SSRGQEEISGALPVASPASSR 21 1 H0Y9D5;H0Y8S9;Q9UBK8;Q9UBK8-1 H0Y9D5 MTRR Methionine synthase reductase 1 S(0.499)S(0.499)RGQEEIS(0.002)GALPVASPASSR;S(0.424)S(0.424)RGQEEIS(0.128)GALPVAS(0.023)PASSR;S(0.499)S(0.499)RGQEEIS(0.003)GALPVASPASSR 103.45 0.0005297999999999999 68691000.0 104630.0 94415.0 117805.0 103693.0 119530.0 133223.0 105819.0 112035.0 146272.0 92053.0 True False 103137.95701320813 94196.38786834036 108119.52764045048 111318.92912970774 112499.48040502184 127525.36284798122 111297.79004365645 117240.55510387593 129797.30704755495 107964.23839708774 0.9552974072198911 0.8724776765607346 1.0014383396360524 1.031072240053059 1.0420068911267977 1.181181516595787 1.030876442941301 1.0859202717910195 1.202225005007363 1.0 16.720193993946232 -5.7756906356481 1.2755951153671599 1.0989254457516293 0.909924227675594 0.5416590866920299 0.06309251738062814 0.3476769488540259 1.1232909660215318 0.021381448441593325 0.053278001994382596 1.6761364261126483e-06 5.7756906356481 -0.18900121807603532 S(ph)SRNIPR ddPTM_PC-9_AZD4547_30min_R2 1 SSRNIPR 7 1 Q5T5P2;Q5T5P2-2;Q5T5P2-7;Q5T5P2-10;Q5T5P1;A0A0U1RQK8;A0A1B0GU17 Q5T5P2 KIAA1217 Sickle tail protein homolog 1 S(0.901)S(0.099)RNIPR 75.043 0.01571 1280500.0 692.81 0.0 490.1 1273.1 659.26 532.52 744.58 675.36 1224.9 0.0 True False 913.1091686567877 0.0 483.60095377434885 979.6064641989266 567.7331286559397 499.22144021765286 810.8461775574115 570.9986302288946 1289.645713317088 0.0 0.0 S(ph)SRNIPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSRNIPR 7 1 Q5T5P2;Q5T5P2-2;Q5T5P2-7;Q5T5P2-10;Q5T5P1;A0A0U1RQK8;A0A1B0GU17 Q5T5P2 KIAA1217 Sickle tail protein homolog 1 S(0.889)S(0.111)RNIPR 65.465 0.02678 1061100.0 679.75 681.59 667.02 1079.1 595.2 496.98 2635.7 2342.8 1256.2 1248.6 True False 670.056640349117 680.011820231765 612.1801903716593 1158.4606137720737 560.1915062082234 475.7253239169641 2772.163649420853 2451.6550408118883 1114.7135276275606 1464.4188463450798 0.45755805589463366 0.46435609725246946 0.4180362687215809 0.7910719099685027 0.3825350292413665 0.3248560513300461 1.8930128196176002 1.674148790785347 0.7611985672061519 1.0 10.516112530307122 -7.2473502791259286 24.992868473916335 1.388269122020919 0.48051085451963466 0.6338778412001147 0.31865825147178495 482.2473420571337 855467.0577653489 0.12218426623693047 0.09417385997906878 5.6578277428397975e-08 7.2473502791259286 -0.9077582675012843 S(ph)SRSDSNFQVPNGGIPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSRSDSNFQVPNGGIPR 17 1 Q9P270;D6RIF6;H0Y9L2 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 S(0.415)S(0.415)RS(0.146)DS(0.024)NFQVPNGGIPR 64.407 0.010796 5662800.0 15032.0 9516.7 14996.0 10047.0 10406.0 10549.0 12873.0 13353.0 12989.0 7498.2 True False 14817.640923468805 9494.664665854305 13763.086766234006 10785.889895809496 9793.939538983152 10097.84386092006 13539.500951927244 13973.429127523113 11526.042039766262 8794.253879276534 1.6849230334805607 1.079644139934176 1.5650090337585567 1.2264701524283042 1.1136748692305047 1.1482320159889183 1.5395849537426685 1.5889271926128028 1.3106333064738018 1.0 13.10234546664252 -5.7990627870301585 24.99962427006974 1.2988744742474025 1.4068384439689574 0.09254663916767703 0.22431584986586167 603.1628818790017 400780.9934896237 0.06501392943870964 0.09643357748428613 1.5883171050557202e-06 5.7990627870301585 0.10796396972155486 S(ph)SS(ph)PVTELASR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSPVTELASR 11 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 S(0.993)S(0.051)S(0.778)PVT(0.178)ELASR;S(0.993)S(0.072)S(0.928)PVT(0.008)ELASR 120.55 0.0042872 0.0 34940.0 40414.0 36638.0 35200.0 38737.0 39939.0 36989.0 39076.0 35930.0 35946.0 True False 34441.74919278873 40320.42386602875 33625.76506676989 37788.72542375774 36458.56581987223 38230.9020723563 38904.10943143302 40891.61361395143 31883.185040326563 42159.21820496576 0.8169446839678821 0.9563845247319975 0.7975898628691661 0.8963336378781989 0.8647827775795408 0.9068218932924436 0.92279010588604 0.9699329198930681 0.7562565530821721 1.0 15.363560493624279 -6.788097512344648 7.122537154864339 0.9101888483364332 0.8692204303547403 0.08759220563347048 0.07191307579919316 0.5231548343693321 94.8645864242869 0.023849313184542375 0.02148433046736311 1.6289302471003755e-07 6.788097512344648 -0.04096841798169293 S(ph)SSAPLIHGLSDLSQVFQPYTLR ddPTM_PC-9_AZD4547_30min_R2 1 SSSAPLIHGLSDLSQVFQPYTLR 23 0 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 S(0.452)S(0.096)S(0.452)APLIHGLSDLSQVFQPYTLR 104.89 1.4544999999999998e-06 4449700.0 2650.7 763.62 3374.8 4573.4 3447.2 3054.2 820.42 4015.9 3161.5 1532.6 True False 3493.56746201491 1010.4452315970138 3330.0479469448514 3519.0732883256383 2968.6157830033007 2863.22039118297 893.4357906358645 3395.334931201461 3328.6104356698283 1478.9441404871332 2.3622037955160375 0.6832206869315527 2.2516387575314396 2.3794497655378177 2.007253486954214 1.9359895433507621 0.6041038103992119 2.295783078110786 2.2506667726973473 1.0 10.530351847738633 S(ph)SSAQEFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSAQEFR 8 0 Q8TE96-2;Q8TE96 Q8TE96-2 DQX1 ATP-dependent RNA helicase DQX1 1 S(0.973)S(0.021)S(0.006)AQEFR 74.173 0.028161000000000002 39594000.0 11348.0 8686.1 10540.0 14618.0 16589.0 16186.0 17067.0 13058.0 12402.0 12022.0 True False 13268.992266783458 9548.398603564949 10791.313573172598 13799.000852195439 13338.504535132904 15337.177666175472 15450.290205620324 12715.241336094648 12583.355787721119 14201.493433900356 0.9343378095087573 0.6723517246976284 0.759871743306424 0.9716584327149617 0.939232524890135 1.0799693523474176 1.0879341864665422 0.8953453659839832 0.8860586280090386 1.0 13.793755031560416 -5.773403490061578 10.341049362620394 0.9827192567478509 0.7771412201995321 0.5015888023875329 0.08706659200943452 0.19018579606159886 153.95683812760944 0.025322776428390998 0.038993674698738795 1.6849868268973438e-06 5.773403490061578 -0.20557803654831874 S(ph)SSASSPEMK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSASSPEMK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.591)S(0.083)S(0.325)AS(0.001)SPEMK 152.69 0.00017112 43867000.0 175180.0 198470.0 145790.0 140130.0 148730.0 187280.0 187120.0 150520.0 189410.0 144420.0 True False 172681.90107592285 198010.45490896024 133803.70896567474 150435.6276599763 139981.99381443055 179270.470971003 196808.15801480826 157513.70870027537 168076.6512242767 169382.80457244648 1.0194771630556236 1.1690115499549985 0.7899485978132199 0.8881399032192415 0.8264238755980632 1.0583746763640784 1.1619134451787385 0.9299273860641822 0.9922887488404342 1.0 17.36992789682101 -6.826565238157084 24.99999999998531 1.0324598285345332 0.9403334354710199 0.13626315979163517 0.11290830733522145 135.67906441623586 52081.50401364432 0.04299597075826081 0.03791889366691827 1.490852788080676e-07 6.826565238157084 -0.09212639306351333 S(ph)SSDALSASFNGEMLGNR ddPTM_PC-9_AZD4547_30min_R2 2 SSSDALSASFNGEMLGNR 18 0 A7KAX9;A7KAX9-2;G3V174 A7KAX9 ARHGAP32 Rho GTPase-activating protein 32 1 S(0.714)S(0.016)S(0.271)DALSASFNGEMLGNR;S(0.684)S(0.136)S(0.181)DALSASFNGEMLGNR 166.52 1.5948e-24 4851400.0 19976.0 25304.6 35934.0 48501.0 41171.0 34304.0 30972.0 36982.0 29470.7 32842.0 True False 26327.95247338809 33483.81709157672 35457.49168114149 37319.84378298025 35455.117313190116 32158.965457121532 33728.44799928571 31267.281661817357 31028.4610363735 31692.21157632679 0.8307388839046609 1.0565314134337096 1.1188077422664708 1.1775714576781744 1.1187328226621494 1.0147277156619576 1.0642503732519548 0.9865919765969616 0.9790563514838739 1.0 14.951840718312537 -7.761913590934772 24.50773411055633 0.9871181088234914 1.0627097100875176 0.10233100705456055 0.08709953656823988 22.052840160937038 1139408.5700360974 0.0467789717968484 0.02463941654439116 1.7301605650284447e-08 7.761913590934772 0.0755916012640262 S(ph)SSDPPAVHPPLPPLR ddPTM_PC-9_AZD4547_30min_R2 2 SSSDPPAVHPPLPPLR 16 0 O43150 O43150 ASAP2 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 1 S(0.461)S(0.078)S(0.461)DPPAVHPPLPPLR;S(0.442)S(0.117)S(0.442)DPPAVHPPLPPLR 102.36 0.0008569 14345600.0 42477.0 43851.0 50048.0 70178.0 63772.0 52407.0 55084.0 65853.0 51993.0 61129.0 True False 55983.8024235135 58024.978196957505 49384.33081921775 53999.54633929172 54918.35858484757 49129.982005345395 59986.36928815238 55676.932001396824 54741.24383418676 58988.892316219484 0.9490566821191232 0.9836593961775929 0.8371801686745544 0.9154188902178131 0.930994911558075 0.832868360063047 1.0169095728495081 0.9438545091325268 0.927992401361556 1.0 15.848155698278585 -7.279436357824071 24.998669496195895 0.967510322293026 0.9097631103730552 0.285958077802552 0.049280466109603675 1285.5197193687977 1785641.2122716685 0.020921157657659634 0.014137772195231857 5.254890154300659e-08 7.279436357824071 -0.05774721191997079 S(ph)SSDPPAVHPPLPPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSDPPAVHPPLPPLR 16 0 O43150 O43150 ASAP2 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 1 S(0.466)S(0.068)S(0.466)DPPAVHPPLPPLR 115.87 0.00068147 0.0 16276.0 17460.0 20991.0 27762.0 28315.0 27610.0 28827.0 20945.0 24259.0 21561.0 True False 19031.205334346807 19193.313410879917 21491.50504881082 26206.585145618395 22766.879010928238 26162.08299537286 26096.297870593375 20395.2159430619 24613.741981480925 25469.838623217907 0.7472055718876153 0.7535702795299061 0.8438021679972287 1.0289262344100163 0.8938760605328023 1.0271789854029116 1.0245961215790507 0.8007595275641024 0.9663878262284482 1.0 14.636502198281274 -5.523411916397585 3.879029207132925 0.9570491692330811 0.7557030089174009 0.619030117771601 0.06756185545771054 0.14509492191385398 4.889768493879157 0.01889080951853158 0.037988431449853116 2.9963192442426766e-06 5.523411916397585 -0.2013461603156802 S(ph)SSDPPAVHPPLPPLR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSDPPAVHPPLPPLR 16 0 O43150 O43150 ASAP2 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 1 S(0.471)S(0.059)S(0.471)DPPAVHPPLPPLR;S(0.46)S(0.081)S(0.46)DPPAVHPPLPPLR 157.37 2.5603000000000002e-05 9254400.0 54100.0 48448.0 61077.0 49516.0 56142.0 65653.0 60982.0 55642.0 71396.0 48609.0 True False 53328.52407927504 48335.821632636274 56055.48482403802 53157.571820533754 52839.83793941879 62845.17423461799 64139.34957278236 58227.330451107715 63354.63064678982 57011.00088257885 0.9354076099998959 0.8478332406791073 0.9832397950615034 0.9324090262863178 0.9268358232869637 1.10233416817318 1.1250346175273298 1.021334997626757 1.1112702753153982 1.0 15.798952709132296 -6.7549118926016485 24.809710741539373 1.0766432423670622 0.9244809978879086 0.7037420851688077 0.047591216275306825 74.94419742543504 284848.32572789385 0.01556253345995573 0.0152079739292787 1.7582802885076063e-07 6.7549118926016485 -0.1521622444791536 S(ph)SSEAKPTSLGLAGGHK ddPTM_PC-9_AZD4547_30min_R2 2 SSSEAKPTSLGLAGGHK 17 1 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 S(0.797)S(0.162)S(0.04)EAKPTSLGLAGGHK;S(0.548)S(0.428)S(0.023)EAKPTSLGLAGGHK 101.23 0.00051063 26849000.0 69074.0 55667.0 108619.0 185461.0 156814.0 127092.0 102812.0 143291.0 114280.0 130247.0 True False 91038.09517154639 73660.2691224836 107178.64108960608 142705.83179388658 135043.08290667218 119144.91714891822 111962.06882676513 121148.66844960998 120320.6074927559 125687.09217410121 0.7243233461510973 0.5860607310450759 0.8527418308090277 1.135405627780863 1.0744387555693553 0.9479487120593035 0.8908000566333077 0.963891091392228 0.9573028177474924 1.0 16.939476969759234 -5.480458931541843 4.81674339432699 0.9919604939872347 0.6627138159404259 0.7792735834398454 0.07209498967437045 0.0951619613558055 5.103153318579285 0.02109390537196212 0.04363195251342458 3.307813904658917e-06 5.480458931541843 -0.32924667804680885 S(ph)SSEDAESLAPR ddPTM_PC-9_AZD4547_30min_R2 1 SSSEDAESLAPR 12 0 H0YA82;Q4G0J3;Q4G0J3-3 H0YA82 LARP7 La-related protein 7 1 S(0.677)S(0.008)S(0.314)EDAESLAPR 191.48 0.00010445 100500000.0 34840.0 37028.0 59150.0 63796.0 61466.0 44870.0 46643.0 69148.0 52178.0 53292.0 True False 45918.39528298161 48996.57687799462 58365.63235207654 49088.81783837466 52932.50688039013 42064.27180681679 50794.13664053606 58462.76546296442 54936.02255650175 51426.263300822364 0.8928977595431734 0.9527539769200208 1.134938232059789 0.9545476316493265 1.0292893841179334 0.8179531061931955 0.9877080966083687 1.1368270162072913 1.0682483818656772 1.0 15.650217708950034 -7.621956986658327 7.415986618577485 1.0759626402757527 0.9678623285881336 0.23724082644152633 0.08351683651782654 0.3339581526112514 21.85743135202792 0.040689315390301586 0.02332869148346043 2.3880477879418927e-08 7.621956986658327 -0.10810031168761913 S(ph)SSEDAESLAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSEDAESLAPR 12 0 H0YA82;Q4G0J3;Q4G0J3-3 H0YA82 LARP7 La-related protein 7 1 S(0.979)S(0.019)S(0.002)EDAESLAPR;S(0.947)S(0.049)S(0.004)EDAESLAPR 148.89 6.8713e-05 60084000.0 41772.0 43248.0 46226.0 53846.0 57540.0 66447.0 69128.0 56825.0 57885.0 42589.0 True False 48843.17456539291 47541.375623925196 47328.20315308122 50829.1831910874 46265.450054346096 62962.40234674178 62579.695396620475 55333.40396106432 58731.458617338896 50310.04856566151 0.9708433197325554 0.9449677942941593 0.9407306194767715 1.0103187065054877 0.9196065472678552 1.2514876081776627 1.2438806397681248 1.0998479536120234 1.1673902190868746 1.0 15.618558961846393 -6.753187605064134 24.999747369517298 1.1644717454687097 0.9586343138961517 0.6542893787035914 0.07068529621915115 106.87613926294674 323793.77202164754 0.023058057201097243 0.022684159151315025 1.7652750983814106e-07 6.753187605064134 -0.20583743157255796 S(ph)SSEDAESLAPR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSEDAESLAPR 12 0 H0YA82;Q4G0J3;Q4G0J3-3 H0YA82 LARP7 La-related protein 7 1 S(0.53)S(0.01)S(0.46)EDAESLAPR;S(0.503)S(0.093)S(0.395)EDAES(0.01)LAPR 162.93 8.1305e-05 265040000.0 129215.0 112718.0 140181.0 113783.0 229291.0 271370.0 229850.0 250350.0 306850.0 209950.0 True False 127372.37040487096 112457.00839637314 128655.85929430841 122150.981388961 215804.55418345061 259764.13769436735 241750.5083353124 261982.17494760826 272289.3217262515 246239.57775920958 0.5172700975365733 0.45669753587029593 0.5224824557655682 0.49606558986390414 0.8764007644395797 1.054924395412922 0.9817695048669759 1.0639320345318042 1.105790239749823 1.0 17.909703137347734 -6.385329578091101 2.6498435456283587 1.0411678325349887 0.4900697298877229 0.9776590147450249 0.03879430258120179 0.038012296999657524 0.519120221236223 0.013336566480510162 0.015503238729342486 4.117849045066019e-07 6.385329578091101 -0.5510981026472658 S(ph)SSENDVELLTK ddPTM_PC-9_AZD4547_30min_R2 1 SSSENDVELLTK 12 0 Q9C0D6 Q9C0D6 FHDC1 FH2 domain-containing protein 1 1 S(0.721)S(0.043)S(0.236)ENDVELLTK 78.985 0.015877000000000002 2531300.0 10411.0 10145.0 14831.0 17224.0 17675.0 17404.0 16121.0 18894.0 16041.0 18878.0 True False 13721.481437747472 13424.172853712194 14634.331249596753 13253.27290814729 15221.131342708088 16315.725128723852 17555.73776948487 15974.366440927404 16888.894511649443 18217.086966016006 0.7532203948603259 0.7369000806086616 0.8033299328754983 0.7275187812887584 0.8355414546301021 0.8956275588496039 0.9636962156592388 0.8768891794131302 0.9270908429627466 1.0 14.1530046605512 -6.631342047270613 2.1331465155316804 0.9314763466547995 0.7568641328037196 0.8441349514388868 0.03611526219237959 0.11787397258628778 1.0952250484882968 0.01310592707337716 0.013150806185009902 2.3369959121504447e-07 6.631342047270613 -0.17461221385107994 S(ph)SSENDVELLTKK ddPTM_PC-9_AZD4547_30min_R2 1 SSSENDVELLTKK 13 1 Q9C0D6 Q9C0D6 FHDC1 FH2 domain-containing protein 1 1 S(0.438)S(0.438)S(0.124)ENDVELLTKK 71.402 0.011909999999999999 3343900.0 6865.0 9283.5 15614.0 21592.0 22166.0 13960.0 13772.0 12181.0 12211.0 15515.0 True False 9047.92719912942 12284.2098262629 15406.948157993636 16614.297993074564 19088.633513010907 13087.078993161635 14997.681320100839 10298.706341533649 12856.448530749427 14971.82457239846 0.6043302975784173 0.8204884960320499 1.02906282954967 1.1097042924016163 1.2749704233244927 0.8741138349489161 1.0017270271620766 0.6878724962166595 0.8587095359406717 1.0 13.869962428677846 -10.765491580121626 16.65546696627561 0.9999999965742198 0.928849326442389 0.01401199774445383 0.18732386513590193 0.0 0.0 0.19630740308859235 0.04761153870735112 1.7159649780462262e-11 10.765491580121626 -0.07115067013183074 S(ph)SSESYTQSFQSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSESYTQSFQSR 13 0 Q9BTU6;E9PAM4 Q9BTU6 PI4K2A Phosphatidylinositol 4-kinase type 2-alpha 1 S(0.593)S(0.06)S(0.347)ESYTQSFQSR 183.28 5.8523e-05 16258000.0 25087.0 25933.0 19681.0 11429.0 18538.0 15280.0 14098.0 11868.0 28016.0 10825.0 True False 24729.254779607636 25872.953731818765 18062.904150856986 12269.526786026338 17447.631287110282 14626.510019419718 14827.925457956222 12419.430606264079 24860.543058441108 12696.086826594172 1.947785574985821 2.037868367253392 1.422714289651917 0.966402242959277 1.374252675285992 1.1520486760362996 1.1679130475775057 0.9782093314177257 1.9581264209981897 1.0 13.632096279239443 -5.359654903578499 3.8639702447738844 1.2259139363656968 1.9965409698120793 0.5435867757879387 0.27532704113514034 0.15759811651959704 4.21074586502931 0.07018645637997858 0.16158803188825024 4.368628316244722e-06 5.359654903578499 0.7706270334463825 S(ph)SSETILSSLAGSDIVK ddPTM_PC-9_AZD4547_30min_R2 1 SSSETILSSLAGSDIVK 17 0 Q01850 Q01850 CDR2 Cerebellar degeneration-related protein 2 1 S(0.25)S(0.25)S(0.25)ET(0.25)ILSSLAGSDIVK 76.34100000000001 0.0047529 2344200.0 10815.0 11138.0 18993.0 23941.0 17828.0 18518.0 16161.0 23696.0 18903.0 17735.0 True False 14253.945034025448 14738.140684538828 18741.140410194257 18421.77233476279 15352.889933680333 17360.066532619418 17599.297691994594 20034.3276799098 19902.173988760638 17114.10304811388 0.8328771302797755 0.8611693316970589 1.0950699757683 1.076408870682418 0.8970899550223493 1.0143719763644081 1.0283505739399055 1.1706326427733968 1.1629107253128306 1.0 14.062898062084317 -3.578296905980515 0.5427568603190149 1.074322818556812 3.4585006217659886e-16 0.46748813182125104 0.08236885332846809 13.17691981193745 1.0822123011643405 0.04695308888959362 11.946303745631196 0.00026406028885427474 3.578296905980515 -1.0743228185568117 S(ph)SSETILSSLAGSDIVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSETILSSLAGSDIVK 17 0 Q01850 Q01850 CDR2 Cerebellar degeneration-related protein 2 1 S(0.433)S(0.433)S(0.121)ET(0.014)ILSSLAGSDIVK 86.258 0.0017545000000000002 2403600.0 12387.0 11157.0 10379.0 14375.0 13576.0 12379.0 13346.0 12350.0 11827.0 8750.5 True False 14483.874445598045 12264.593225955741 10626.474722576697 13569.615354378808 10915.880256131431 11729.823448015954 12081.770263327411 12025.825585906643 11999.947500514249 10336.896381080116 1.4011821258175954 1.1864870047845248 1.0280140509124773 1.312735936795847 1.056011384240152 1.1347529292724021 1.1688005584965504 1.163388423619861 1.1608849559987906 1.0 13.335515465807143 -4.7875583879656505 3.967762974505982 1.1378707541641409 1.4233794543164002 0.48267407710284416 0.08410800451909564 0.1873753529337868 5.481636649990316 0.019673439217716512 0.15198880662437356 1.6309536237664684e-05 4.7875583879656505 0.2855087001522594 S(ph)SSETILSSLAGSDIVK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSETILSSLAGSDIVK 17 0 Q01850 Q01850 CDR2 Cerebellar degeneration-related protein 2 1 S(0.275)S(0.275)S(0.224)ET(0.224)ILS(0.001)S(0.001)LAGSDIVK 68.189 0.010067 2113100.0 15685.0 12485.0 14216.0 14270.0 11500.0 15172.0 12277.0 10263.0 13768.0 12522.0 True False 15461.329023723283 12456.09174957611 13047.215355346927 15319.463403324526 10823.5926098699 14523.128927659427 12912.642988177651 10739.856446923517 12217.302856532604 14686.411015483814 1.0527642871646774 0.8481372158550997 0.8883869136980648 1.043104635106105 0.7369800966661383 0.9888820973584193 0.8792238603811314 0.7312784883659144 0.8318780431551288 1.0 13.842194260618985 -4.755319062343604 24.96605448805174 0.8784834386146649 1.05276457825909 0.2063034542041573 0.0994677643449701 321.0565689256463 1309528.6946905742 0.02438525978513986 0.21806699965966345 1.7566325976806787e-05 4.755319062343604 0.17428113964442504 S(ph)SSFGSVSTSSNSSK ddPTM_PC-9_AZD4547_30min_R2 1 SSSFGSVSTSSNSSK 15 0 E5RG30;E5RJ65;E5RHF1;E5RGS8;E5RH07;E5RGQ6;A0A0C4DGW2;P57768-2;P57768 E5RG30 SNX16 Sorting nexin-16 1 S(0.918)S(0.078)S(0.003)FGS(0.001)VSTSSNSSK 238.65 3.7651e-32 15131000.0 83139.0 71062.0 103660.0 156270.0 132710.0 103410.0 90584.0 128710.0 100620.0 107190.0 True False 109575.47260137202 94031.40180685018 102285.40066975927 120244.36584743243 114285.50724134591 96943.75635263923 98645.8005155398 108820.8269615625 105938.56778019869 103437.31072609693 1.0593418548122255 0.9090665751727276 0.9888636890474857 1.1624854223621568 1.1048770162245916 0.9372223201872224 0.9536771579140809 1.0520461736454187 1.024181381326948 1.0 16.658397146455556 -6.766782713185366 24.99443765439937 0.9941940431723535 1.0407955175629497 0.11891890464744248 0.06962434455910298 386.88382133501096 1809706.4371092408 0.02714544058813263 0.024633320061292038 1.7108710863755182e-07 6.766782713185366 0.046601474390596254 S(ph)SSFPYTTK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSFPYTTK 9 0 O43524;O43524-2 O43524 FOXO3 Forkhead box protein O3 1 S(0.764)S(0.048)S(0.188)FPYTTK 169.76 0.0018399999999999998 10763000.0 49468.0 39723.0 37963.0 33476.0 68863.0 51664.0 71618.0 51047.0 59184.0 78914.0 True False 48762.57724867981 39631.02383407386 34841.8286814178 35937.936712662355 64812.61372986705 49454.451154666225 75326.02961043468 53418.82997623549 52518.07468485076 92554.17975370468 0.52685440439796 0.4281926968564328 0.3764479224399715 0.3882908022986813 0.7002667400039574 0.5343297437918972 0.8138587561456898 0.5771628047311098 0.5674306100989309 1.0 16.498010523332816 -6.263208204726591 24.979702645116408 0.6752248700319023 0.4259998579474941 0.485247229889052 0.134337770841828 142.6886041323616 2015074.526231311 0.03905748762229301 0.046603200982850604 5.454962825129949e-07 6.263208204726591 -0.24922501208440823 S(ph)SSFSELCHR ddPTM_PC-9_AZD4547_30min_R2 3 SSSFSELCHR 10 0 Q5T8I3-2;Q5T8I3 Q5T8I3-2 FAM102B Protein FAM102B 1 S(0.474)S(0.474)S(0.052)FSELCHR;S(0.333)S(0.333)S(0.333)FSELCHR;S(0.333)S(0.333)S(0.333)FSELCHR 180.97 0.00074236 12297300.0 46959.0 44547.0 81403.0 104342.0 107978.0 91775.0 60875.0 110402.0 72062.0 86712.0 True False 61890.98519212207 58945.94658593563 80323.54303222465 80287.56396783 92987.11853595094 86036.29474193486 66292.75706949881 93341.90768557558 75871.05020251115 83676.23927307883 0.7396482649051637 0.7044526271497997 0.9599325176420442 0.9595025381794487 1.1112726784061828 1.028204607297825 0.7922530654508895 1.1155127010542705 0.9067215599270025 1.0 16.352530392415368 -5.301215080634262 4.719367583637621 0.9885693859297618 0.7198950364297163 0.579253438989989 0.08945163496226922 0.1268820617764288 6.834988693585645 0.023355200831241988 0.05369324903674733 4.997869584528444e-06 5.301215080634262 -0.26867434950004554 S(ph)SSFSELCHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSFSELCHR 10 0 Q5T8I3-2;Q5T8I3 Q5T8I3-2 FAM102B Protein FAM102B 1 S(0.428)S(0.428)S(0.145)FSELCHR;S(0.455)S(0.455)S(0.091)FSELCHR 191.52 4.351899999999999e-37 3175700.0 26453.0 30658.0 36474.0 35622.0 53109.0 42226.0 34523.0 38060.0 33865.0 29367.0 True False 30930.970429434517 33701.523628336574 37343.67848841531 33626.214828082186 42702.67269614646 40011.59422537536 31252.73151512455 37060.96532790335 34360.211558714356 34691.00463095592 0.8916135683725285 0.9714773033198237 1.0764657549032848 0.9693064581380388 1.230943674027862 1.1533708709511314 0.900888626535673 1.0683162889676778 0.9904645865474191 1.0 15.082274000372974 -4.946647451125989 2.285607027960212 1.053806017597555 0.8770038541487507 0.23534784700862743 0.08934566595033734 0.6323609710868362 5.148834826549663 0.024789708431667803 0.1979645908631992 1.1307134257304967e-05 4.946647451125989 -0.17680216344880428 S(ph)SSFSELCHR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSFSELCHR 10 0 Q5T8I3-2;Q5T8I3 Q5T8I3-2 FAM102B Protein FAM102B 1 S(0.476)S(0.476)S(0.048)FSELCHR 204.17 4.4612e-05 3775700.0 19770.0 24357.0 41426.0 30101.0 32692.0 30782.0 22617.0 28234.0 38836.0 23816.0 True False 19488.076174626036 24300.602862989614 38020.114188984364 32314.727953992402 30769.120834944955 29465.525616346724 23787.99759416907 29545.854713284494 34461.88071878994 27932.563867174762 0.6976830436080251 0.8699739479177103 1.361139434596052 1.156883704183252 1.1015501828352965 1.054880810671785 0.8516224184534589 1.0577566332178197 1.2337528657470704 1.0 14.76966038097603 -5.024350755344066 9.738813415872064 1.0969802105693285 0.7399606946465945 0.5120006316910333 0.12915259394775655 0.3035055465027558 121.67896969060465 0.03486456575051072 0.09889276541381015 9.454732471016525e-06 5.024350755344066 -0.35701951592273395 S(ph)SSKESLVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSKESLVR 9 1 Q13439-3;Q13439-4;Q13439;Q86W71;Q13439-5;E7EVX2 Q13439-3;Q13439-5 GOLGA4 Golgin subfamily A member 4 1 S(0.403)S(0.403)S(0.163)KES(0.03)LVR 54.722 0.044308999999999994 133550000.0 96260.0 103460.0 101520.0 119670.0 135890.0 142400.0 149150.0 157120.0 118700.0 105150.0 True False 112554.91677833778 113730.82505668022 103940.62181674382 112965.27787537451 109263.32999452733 134932.29331912706 135021.4322475109 152995.76648240112 120435.76294166237 124212.86263305804 0.9061454215964779 0.9156123017038644 0.8367943513531185 0.9094491140510105 0.8796458569456393 1.0862988780617326 1.087016508478537 1.231722409734423 0.969591718511844 1.0 16.922455051345302 -6.763783022431157 24.693225426214596 1.0901642565410963 0.8891553640935667 0.6434906591280799 0.06852989608817475 30.414089626243804 320447.3612336183 0.022662834056743304 0.02094379134963568 1.722729051499336e-07 6.763783022431157 -0.20100889244752962 S(ph)SSLDGEHHDGYHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSLDGEHHDGYHR 14 0 Q9C0J8 Q9C0J8 WDR33 pre-mRNA 3 end processing protein WDR33 1 S(0.454)S(0.454)S(0.092)LDGEHHDGYHR 73.296 0.017955000000000002 4043600.0 3216.7 4271.5 3748.4 4325.1 6509.0 5383.5 7668.0 4308.5 5875.4 4986.4 True False 3761.2237772790236 4695.54629063995 3837.7760718861637 4082.7786691633933 5233.608175247457 5101.179782889888 6941.6315284875345 4195.406440233096 5961.316609835243 5890.394847679315 0.6385350854299457 0.797153062241641 0.6515312082004422 0.6931247861545169 0.8884987017991474 0.8660166109067612 1.1784662502246999 0.7122453670293415 1.0120402390654457 1.0 12.524148629362319 -6.410608300031662 2.3421808988278214 0.9498042550732517 0.6968253847978383 0.5213094418199142 0.11751340142097025 0.25686444882159115 2.7681486417296752 0.039464163221327106 0.04556129988093881 3.8850060546292165e-07 6.410608300031662 -0.25297887027541344 S(ph)SSLDGEHHDGYHR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSLDGEHHDGYHR 14 0 Q9C0J8 Q9C0J8 WDR33 pre-mRNA 3 end processing protein WDR33 1 S(0.453)S(0.453)S(0.094)LDGEHHDGYHR 85.006 0.006095000000000001 5160000.0 2666.1 2888.3 2785.4 2374.5 2593.6 2785.1 3081.9 3792.4 4371.6 1415.2 True False 2628.0809250971406 2881.6123188066226 2556.3951639549323 2549.1286510997934 2441.04954721379 2665.9877653852013 3241.4657021474854 3968.6087488368657 3879.2243730111795 1659.815434364533 1.583357324366195 1.7361040626242032 1.5401683289766843 1.5357904248406615 1.4706752911647405 1.606195309544091 1.952907314293347 2.3909940025086365 2.3371420054883125 1.0 10.696807112541089 -7.297159235437062 4.215914481867776 2.0461460579055513 1.5749727449606794 0.14298880869065544 0.3660916170393579 0.29610401526197727 12.08278667185506 0.14979029869834937 0.10179823457412435 5.044762958301021e-08 7.297159235437062 -0.47117331294487186 S(ph)SSLEGFHNHFK ddPTM_PC-9_AZD4547_30min_R2 2 SSSLEGFHNHFK 12 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 S(0.437)S(0.437)S(0.125)LEGFHNHFK;S(0.333)S(0.333)S(0.333)LEGFHNHFK 122.46 0.00034500000000000004 20946600.0 27082.3 34355.0 84877.0 139105.0 142094.0 129327.0 92127.0 141680.0 102577.0 130519.0 True False 35693.90805316571 45459.58190135857 83751.47552235346 107036.4914008261 122366.70082097694 121240.16224560294 100326.12452635264 119786.6114825125 107999.01080490403 125949.56953689146 0.28339841243134006 0.3609347937314161 0.6649603951033918 0.8498361034054539 0.9715531483824161 0.9626087861307926 0.796557899286559 0.9510680498786953 0.8574782049832287 1.0 16.942486665758246 -5.415243639163534 1.6998139875970897 0.9171323652322045 0.2677294582238722 0.945235163427306 0.05700113533777272 0.08530850309343063 0.4530678439019394 0.017061330318449495 0.05921269890131022 3.843760865999883e-06 5.415243639163534 -0.6494029070083324 down S(ph)SSLEGFHNHFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSLEGFHNHFK 12 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 S(0.333)S(0.333)S(0.333)LEGFHNHFK 126.32 0.00023046 8061200.0 19371.0 28301.0 35903.0 51359.0 63988.0 75415.0 61437.0 63351.0 64820.0 54986.0 True False 22650.127705310402 31110.536245206913 36759.06368288575 48481.521738124604 51450.010741701386 71460.10463948011 55617.24259463857 61688.10337593292 65767.86987260781 64954.5265310635 0.3487074560458589 0.4789587101420681 0.5659199696468621 0.7463917347613805 0.7920927684246334 1.100155885291619 0.8562489108136364 0.9497121551094909 1.01252173458851 1.0 15.987142446814108 -5.747999095744308 0.8592182773415785 0.982019504957961 0.3257554932436707 0.9117143564687094 0.07050604134650154 0.21912145750979947 0.29060910534926454 0.0307126864195875 0.10456013508473772 1.7864912945475752e-06 5.747999095744308 -0.6562640117142903 down S(ph)SSLEGFHNHFK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSLEGFHNHFK 12 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 S(0.495)S(0.495)S(0.011)LEGFHNHFK 126.32 0.00023046 8746600.0 55444.0 36976.0 81142.0 60696.0 80215.0 107110.0 80544.0 99421.0 139890.0 125360.0 True False 54653.358392815666 36890.38434379869 74470.81797717774 65159.78631592047 75496.91140875785 102529.15498560497 84714.17421518119 104040.46261420457 124134.11509299414 147028.3089682997 0.3717199685986955 0.2509066764261874 0.506506661878524 0.4431785060519832 0.5134855453247136 0.6973429518781376 0.5761759406036979 0.7076219766401339 0.844287171389275 1.0 17.165734434097935 -6.919722851626892 0.22806786983112795 1.085905829950633 0.09376499434010248 0.8983191959229365 0.06804141306805196 1.0882698204889023 0.1443308365111507 0.16475799353341172 0.35680213334380884 1.2030319137991216e-07 6.919722851626892 -0.9921408356105306 down S(ph)SSLGNLK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSLGNLK 8 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6;H0YGH8 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.745)S(0.104)S(0.151)LGNLK 73.84100000000001 0.028852 18047000.0 50288.0 64849.0 64623.0 57177.0 72497.0 65240.0 66735.0 55188.0 69197.0 54364.0 True False 49570.883898310276 64698.84612481068 59309.946391993864 61381.98731688061 68232.8689945859 62449.83728186796 70190.21176313724 57752.235953699215 61403.30518328626 63760.74496452336 0.7774514542747524 1.0147128324929278 0.9301953172754501 0.9626924426782294 1.0701391433326388 0.9794402075542752 1.1008373851684332 0.9057647614662079 0.9630267842298772 1.0 15.960380865062666 -4.75766429026512 24.994361886657284 0.9915467537058555 0.7774511477154755 0.566635688731238 0.056253370067153 82.2639680002792 544579.6183249481 0.014063184313914647 0.10244023333339225 1.7471721955726026e-05 4.75766429026512 -0.21409560599038002 S(ph)SSLGSTPHEELER ddPTM_PC-9_Lapatinib_30min_R1 1 SSSLGSTPHEELER 14 0 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 S(0.394)S(0.394)S(0.21)LGS(0.001)TPHEELER 76.574 0.0091491 3900800.0 8794.5 9871.1 11220.0 9866.0 12356.0 17715.0 11662.0 13054.0 15661.0 14263.0 True False 8669.088817286218 9848.24407442857 10297.534910452485 10591.578552011186 11629.244372830652 16957.370745681965 12265.80129739576 13660.536495969951 13897.093262358878 16728.34054574713 0.5182276624258568 0.5887161399839091 0.6155742036869546 0.633151777550577 0.6951821874398157 1.0136911488206797 0.733234791810483 0.8166103779757693 0.8307514558514865 1.0 14.030006716428156 -6.551286487222913 5.699072563363892 0.859267823215395 0.5984927737110651 0.7261247419534236 0.0839665778916077 0.10181649890742393 9.6329192653395 0.027776802636823944 0.028314272498645487 2.810046540167009e-07 6.551286487222913 -0.26077504950432984 S(ph)SSLSDLTHR ddPTM_PC-9_AZD4547_30min_R2 2 SSSLSDLTHR 10 0 Q5T9C2-3;Q5T9C2-2;Q5T9C2 Q5T9C2-3 FAM102A Protein FAM102A 1 S(0.468)S(0.468)S(0.064)LSDLTHR;S(0.393)S(0.393)S(0.214)LSDLTHR 126.76 0.00019002 8325100.0 20417.9 20689.5 44638.0 57183.0 48772.0 46001.0 27758.0 49741.0 34632.0 39102.0 True False 26910.3674812971 27376.976269776085 44046.07095404891 44000.34281854312 42000.84966600051 43124.55019802495 30228.40822562873 42054.67138446967 36462.57681737071 37733.05088172252 0.7131776215405945 0.7255436713980951 1.1673074380366193 1.1660955525824286 1.113105054708027 1.142885327062541 0.8011122217597052 1.1145314360159648 0.9663299406047441 1.0 15.20354113259932 -5.249444201084484 24.27313993781406 1.0625653725209587 0.7193605366379306 0.6158561418586967 0.1072405387304088 335.02139709414155 677935.882821805 0.028281322512935605 0.0734913740262931 5.6306145586886865e-06 5.249444201084484 -0.3432048358830281 S(ph)SSLSDLTHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSLSDLTHR 10 0 Q5T9C2-3;Q5T9C2-2;Q5T9C2 Q5T9C2-3 FAM102A Protein FAM102A 1 S(0.47)S(0.47)S(0.06)LSDLTHR 133.05 3.0692e-05 0.0 6944.3 8602.7 11222.0 11434.0 14377.0 14860.0 11790.0 12277.0 13558.0 9060.0 True False 8119.832833823087 9456.719202736347 11489.575039671996 10793.390049528161 11559.930056158051 14080.715440465076 10673.165847791868 11954.741758556747 13756.260100783975 10702.506281079466 0.7586851734138026 0.8835985660157475 1.0735406023525496 1.0084918210802047 1.0801142977691487 1.3156465477023649 0.997258545567082 1.1170039469811905 1.2853307196934907 1.0 13.385661061772396 -4.622202093444629 0.7547413561846328 1.1393886970031182 0.43113640875027487 0.5817335025973451 0.10254759169111238 2.377621846161065 0.8759580450292137 0.040297236396914654 1.508065187388833 2.3867004036181993e-05 4.622202093444629 -0.7082522882528433 S(ph)SSLSDLTHR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSLSDLTHR 10 0 Q5T9C2-3;Q5T9C2-2;Q5T9C2 Q5T9C2-3 FAM102A Protein FAM102A 1 S(0.365)S(0.365)S(0.271)LSDLTHR 123.84 0.00024524 4187600.0 17664.0 18863.0 28868.0 18704.0 25875.0 35542.0 26371.0 25087.0 35141.0 21965.0 True False 17412.108120819117 18819.32388243927 26494.584473702536 20079.554554714905 24353.083372207304 34021.95151244865 27736.361345706006 26252.633604596143 31183.05052886489 25761.62098347722 0.6758933427359541 0.7305178464705095 1.0284517612729192 0.7794367663274515 0.9453241854550491 1.3206448279892549 1.0766543519716918 1.019059849589195 1.2104459788793889 1.0 14.652935753718117 -6.539646240010291 8.975677169016878 1.1248563602306567 0.8202137045366487 0.6076077461612089 0.12193196342100257 0.149859802082358 69.05971126850936 0.04061495637611685 0.04115706410397706 2.8863816840313786e-07 6.539646240010291 -0.30464265569400806 S(ph)SSLVDIREEETEGGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSLVDIREEETEGGSR 17 1 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 1 S(0.813)S(0.185)S(0.002)LVDIREEETEGGSR 110.6 0.005231899999999999 0.0 7538.4 6464.5 9796.7 12073.0 10811.0 8977.4 8165.7 9335.3 8160.0 9764.0 True False 8814.502229813213 7106.25283760786 10030.290482191653 11396.58895119411 8692.662157412855 8506.609340190525 7392.185781451573 9090.258266567958 8279.324562796677 11534.135908218523 0.7642100197148307 0.6161062167252925 0.8696178510472274 0.9880747931081334 0.7536465866696606 0.7375159620001732 0.6408963653865352 0.7881178389870362 0.7178105606417673 1.0 13.493622306619951 -10.702018191348252 3.634116886952003 1.0002288257046206 0.765351888264379 0.3295806137587053 0.10096135625359028 52536269.09665788 86434027.46112376 146982.07362314925 0.027157574897020073 1.986011727289035e-11 10.702018191348252 -0.23487693744024152 S(ph)SSMELHR ddPTM_PC-9_AZD4547_30min_R2 1 SSSMELHR 8 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5;X6R5W5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 S(0.381)S(0.381)S(0.237)MELHR 82.287 0.011568 2621600.0 2719.1 9309.2 12614.0 10318.0 10550.0 13485.0 10845.0 14272.0 12647.0 12079.0 True False 3583.717239206524 12318.216848672022 12446.730118158821 7939.3445115109025 9085.314606255748 12641.780818251045 11810.183990451173 12066.590337933521 13315.494600637778 11656.117886561453 0.3074537572529406 1.0568026995397768 1.0678280915903295 0.6811311097551883 0.779446012358057 1.084561853378815 1.0132176171680063 1.035215193889323 1.1423610099199022 1.0 13.50879975313328 -6.760786258283956 24.999959835381027 1.0546562641311157 0.8046525809005014 0.3143251258855767 0.20238812894359018 24.95840866050177 955362.5644579204 0.06921721816631289 0.06531761592811688 1.7346575141255263e-07 6.760786258283956 -0.2500036832306143 S(ph)SSMELHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSMELHR 8 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5;X6R5W5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 S(0.465)S(0.465)S(0.069)MELHR 75.387 0.018335 3367500.0 9953.3 14681.0 20559.0 19437.0 28660.0 21758.0 17409.0 22827.0 20938.0 20357.0 True False 11638.19710336409 16138.43265665109 21049.204530441675 18348.007905604234 23044.27873753145 20616.972177230087 15759.893489754746 22227.815437205743 21244.178639195678 24047.56295407666 0.4839657609209471 0.6711047055982537 0.875315497484676 0.7629882471102457 0.9582791728849543 0.8573414369099301 0.6553634361973071 0.9243271544669176 0.8834233506224904 1.0 14.553603074284135 -4.901627392811467 1.8560658601202358 0.8565350086562915 0.4128811824361317 0.6283737718466176 0.09339016644290252 0.420170317287075 1.852608332832291 0.025494915349536913 0.30238875742152216 1.2542167809878028e-05 4.901627392811467 -0.4436538262201598 S(ph)SSMELHR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSMELHR 8 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5;X6R5W5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 S(0.445)S(0.445)S(0.11)MELHR 70.908 0.025555 1560300.0 5152.5 8638.8 8947.7 9455.9 8914.0 8189.8 7071.2 9804.6 8659.7 7022.0 True False 5079.0244051472255 8618.797389366287 8212.054645120832 10151.3184299577 8389.69604559829 7839.541345356258 7437.31213635267 10260.15750945204 7684.353395316339 8235.743343773143 0.6167050371946522 1.046511168403853 0.9971236720641347 1.232592858498059 1.0186932369549309 0.9518923815521224 0.9030529274538225 1.2458083115484055 0.9330491583526946 1.0 13.007683155618748 -4.761048044290927 24.97316320026836 1.0417292312432405 0.616704558629196 0.5659363086552059 0.11021562650253931 6.757228159336666 430671.3884159151 0.027066493635586875 0.15441833543775133 1.7336122044438894e-05 4.761048044290927 -0.4250246726140444 S(ph)SSMSSIDLVSASDDVHR ddPTM_PC-9_AZD4547_30min_R2 1 SSSMSSIDLVSASDDVHR 18 0 A0A2U3TZL3;Q9Y5P4;Q9Y5P4-3;A0A0A0MRE4;A0A2R8YFA1 A0A2U3TZL3 COL4A3BP Collagen type IV alpha-3-binding protein 1 S(0.268)S(0.268)S(0.268)MS(0.15)S(0.045)IDLVSASDDVHR 73.796 0.0046409 5139400.0 3703.0 2420.2 12610.0 20687.0 14445.0 13521.0 12640.0 14816.0 11283.0 11636.0 True False 4880.476972815183 3202.4823204094887 12442.783160772377 15917.931760963951 12439.561088849703 12675.529732560068 13764.93551307541 12526.527637809906 11879.396345298961 11228.627181722759 0.4346459183148686 0.2852069330097881 1.1081304027108445 1.4176204716168814 1.1078434511654305 1.1288583659801694 1.2258787552837351 1.1155885252116828 1.0579562535156108 1.0 13.454893933362072 -5.280066027886943 7.901460676277648 1.1608626183522688 0.35905032199518877 0.8863598952341287 0.11237451211122476 0.04980705116301332 17.6622255468213 0.02905790859123332 0.06374243023378305 5.24727677302764e-06 5.280066027886943 -0.80181229635708 S(ph)SSMSYVDGFIGTWPK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSMSYVDGFIGTWPK 16 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 S(0.335)S(0.335)S(0.274)MS(0.048)Y(0.007)VDGFIGTWPK 58.674 0.046298 9654200.0 77892.0 75839.0 90151.0 84668.0 90895.0 94606.0 92260.0 92967.0 95724.0 93647.0 True False 76781.2457963567 75663.3994550342 82739.13277292337 90894.76716416811 85548.73480644575 90559.9219173575 97036.77136835302 97286.58621271915 84942.55510159254 109833.75917321637 0.6990678127957608 0.6888901920920976 0.7533124004472735 0.8275667504088611 0.7788928964138316 0.8245180953384056 0.883487664437657 0.8857621458561811 0.7733738309696888 1.0 16.74496203247763 -1.9256198823492563 0.09243820894767982 1.0995151357450799 1.9253136862427256e-14 0.7595452574261783 0.04392332217237618 66.75841713940528 0.48196952330206855 0.7872971668902022 9.292186957346923 0.01186807050423783 1.9256198823492563 -1.0995151357450605 S(ph)SSPAELDLKDDLQQTQGK ddPTM_PC-9_AZD4547_30min_R2 1 SSSPAELDLKDDLQQTQGK 19 1 H7C1F9;Q2PPJ7-3;Q2PPJ7-2;Q2PPJ7 H7C1F9 RALGAPA2 Ral GTPase-activating protein subunit alpha-2 1 S(0.35)S(0.35)S(0.301)PAELDLKDDLQQTQGK 78.975 0.0013837 3580500.0 11727.0 16748.0 14552.0 19714.0 17694.0 17744.0 16693.0 20369.0 12410.0 15077.0 True False 15455.942063247 22161.463475009557 14359.030971892102 15169.241878263798 15237.493520671967 16634.46487497564 18178.644661374023 17221.43908305548 13065.967264482862 14549.158819081642 1.0623254756815277 1.523212699138603 0.9869320385079458 1.0426198563705895 1.0473109621078267 1.1433282900973671 1.2494636210536245 1.1836724924927664 0.8980565424405478 1.0 13.828648123568176 -1.5228787452803378 0.12140169350096777 0.9670321701630658 1.7851545876671882 0.1125435733137945 0.1574957092125538 222.26119123239036 1.857921551583667 1.0811461213461853 30.787916895417087 0.02999999999999998 1.5228787452803378 0.8181224175041224 S(ph)SSPAELDLKDDLQQTQGK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSPAELDLKDDLQQTQGK 19 1 H7C1F9;Q2PPJ7-3;Q2PPJ7-2;Q2PPJ7 H7C1F9 RALGAPA2 Ral GTPase-activating protein subunit alpha-2 1 S(0.333)S(0.333)S(0.333)PAELDLKDDLQQTQGK 74.742 0.0020076 4268600.0 20508.0 17979.0 15742.0 18258.0 16178.0 16312.0 16782.0 16849.0 16966.0 12403.0 True False 20215.552159293413 17937.37073012646 14447.753525877282 19600.75422690252 15226.44184717177 15614.373785129212 17650.889845043355 17631.866050298573 15055.110420099647 14546.842024041342 1.3896866499191702 1.233076615562446 0.9931883155120337 1.347423323530197 1.0467180314467748 1.0733858083647005 1.2133829332766521 1.2120751721341758 1.0349401193206262 1.0 13.828418371806723 -4.908372592917691 3.7403514070929 1.129443712006181 1.388101347649091 0.3793277599400887 0.10798445172358265 0.2513722216966656 6.2470217788919715 0.0261852395647112 0.14394562288637874 1.2348875356192441e-05 4.908372592917691 0.25865763564291 S(ph)SSPAGETEGDREPQARPGEGTAPLPPPGQK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSPAGETEGDREPQARPGEGTAPLPPPGQK 31 2 Q9BTC0 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 S(0.255)S(0.255)S(0.247)PAGET(0.231)EGDREPQARPGEGT(0.013)APLPPPGQK 51.538999999999994 0.020836 19314000.0 21989.0 13198.0 12912.0 8957.9 15453.0 16188.0 13069.0 12291.0 13941.0 11061.0 True False 21675.432827711276 13167.440841882697 11850.425201761369 9616.6938486784 14544.08492176693 15495.676976071105 13745.648872891881 12862.084730501514 12370.817774761834 12972.879112143937 1.6708267024103278 1.0149975751764024 0.9134768850708062 0.741292180829481 1.1211146574357718 1.1944670756675417 1.0595681000391466 0.9914595379572521 0.9535907694677804 1.0 13.663211076552967 -4.761715407794957 6.9331896999967695 0.9987741156069947 1.685653909279321 0.7540451438086657 0.11516516222662365 0.05956795317232478 16.140100938804867 0.031763200361600664 0.19294746996084708 1.730950275501758e-05 4.761715407794957 0.6868797936723263 S(ph)SSPAPADIAQTVQEDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSPAPADIAQTVQEDLR 18 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 1 S(0.547)S(0.096)S(0.357)PAPADIAQTVQEDLR 178.02 1.5228e-08 7476000.0 10009.0 8452.1 12039.0 12814.0 15304.0 11837.0 14513.0 13141.0 13032.0 12617.0 True False 11703.32601323895 9291.168630017071 12326.055418161744 12096.073123548525 12305.291060683223 11216.246882152427 13138.223574979073 12796.062674040419 13222.568345878217 14904.362223882956 0.7852282330125726 0.6233858578080432 0.8270099205191285 0.8115793847364774 0.8256167473550163 0.7525479261487189 0.8815018970705235 0.8585447992894208 0.8871609631635355 1.0 13.86344702149192 -4.04943309817951 0.05280292860717014 1.401178113967388 4.6708414266476714e-17 0.6551573161411186 0.05460633960704809 154.87530813232064 1.0462095908526245 8.502597896693278 21.693494037939978 8.924150829860002e-05 4.04943309817951 -1.401178113967388 S(ph)SSPATEQSWMENDFDELREEGFRR ddPTM_PC-9_AZD4547_30min_R2 1 SSSPATEQSWMENDFDELREEGFRR 25 2 Q9UN81 Q9UN81 L1RE1 LINE-1 retrotransposable element ORF1 protein 1 S(0.307)S(0.307)S(0.307)PAT(0.079)EQS(0.001)WMENDFDELREEGFRR 60.56100000000001 0.0080679 4512300.0 8967.1 7194.3 8757.9 14829.0 9499.4 13402.0 11131.0 11508.0 8871.2 9691.9 True False 11818.451272733191 9519.716782795631 8641.764523689793 11410.403155766155 8180.5722815797035 12563.970821371935 12121.637436395751 9729.70302753216 9340.113521086254 9352.589530984767 1.2636555077691711 1.0178696233013518 0.9239969844779311 1.2200260813290191 0.8746852681257724 1.3433681420261185 1.2960728572805675 1.040321826944081 0.9986660368385482 1.0 13.191150156214931 -7.983926844360352 24.841378123856117 1.0060532020891155 1.126263008496159 0.12524797808041555 0.14821655702955214 494.5959468687178 764407.2725289599 0.08353837739269207 0.04011073681408062 1.037703199176057e-08 7.983926844360352 0.12020980640704337 S(ph)SSPCRTPEPDNDAHLR ddPTM_PC-9_AZD4547_30min_R2 1 SSSPCRTPEPDNDAHLR 17 1 Q9Y2K6 Q9Y2K6 USP20 Ubiquitin carboxyl-terminal hydrolase 20 1 S(0.497)S(0.402)S(0.101)PCRTPEPDNDAHLR 73.688 0.0048722 5507900.0 24892.0 16402.0 21609.0 36416.0 32221.0 22767.0 18406.0 25062.0 14398.0 22493.0 True False 32807.138214235914 21703.625741408334 21322.450540930222 28020.853821591485 27747.670324944687 21343.37589092484 20044.09834285333 21189.24376746707 15159.04888590042 21705.52691633636 1.5114647223580684 0.9999124105608975 0.9823512058987234 1.2909547844471807 1.2783688888041136 0.983315262199926 0.9234559667734866 0.9762142079821745 0.6983958023378449 1.0 14.405774824962561 -6.914670249246443 4.61642539273228 0.9038512626926679 1.1914747925934632 0.4624490506471379 0.1606632483874677 0.21655232397408566 8.323301756272834 0.05916135315134091 0.05171503953636185 1.217109776000261e-07 6.914670249246443 0.2876235299007953 S(ph)SSPEDPERDEEVLNHVLR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSPEDPERDEEVLNHVLR 19 1 Q8TE67-2;Q8TE67;Q8TE67-3 Q8TE67-2 EPS8L3 Epidermal growth factor receptor kinase substrate 8-like protein 3 1 S(0.333)S(0.333)S(0.333)PEDPERDEEVLNHVLR 67.579 0.0038171999999999998 1266300.0 2106.2 2360.2 3042.8 2658.8 2598.4 4096.6 3487.7 1814.3 3038.3 1251.6 True False 2076.1652017702245 2354.735101910257 2792.6327295476667 2854.3370214967913 2445.567220650955 3921.3979676410218 3668.2760405528365 1898.5990014277836 2696.094659282612 1467.937392347831 1.4143417918182388 1.6041113975195322 1.902419506516628 1.9444541956462744 1.665988776768943 2.6713659506752574 2.498932215825476 1.2933787308130007 1.8366550735317508 1.0 10.519574723091553 -8.765273118431722 1.2804335949649794 1.0120781754555515 1.921551255712511 0.28843540182673044 0.41147081962025306 1.175808268640041 3.547435982414167 0.41957345415486597 0.12662817255868472 1.7168283712639836e-09 8.765273118431722 0.9094730802569595 S(ph)SSPELVTHLK ddPTM_PC-9_AZD4547_30min_R2 1 SSSPELVTHLK 11 0 Q07960;H0YE29;E9PNR6 Q07960 ARHGAP1 Rho GTPase-activating protein 1 1 S(0.437)S(0.437)S(0.126)PELVTHLK 77.67399999999999 0.019239 46055000.0 67066.0 65677.0 89692.0 128790.0 100320.0 89858.0 94428.0 110710.0 105090.0 104920.0 True False 88391.59294054077 86905.80586626481 88502.62547628822 99099.45528566466 86392.2996492489 84239.16505497991 102831.90906872493 93602.31336271165 110644.84285451278 101246.7827351624 0.8730311280285541 0.8583562214869564 0.8741277805121977 0.9787911537385376 0.8532843939864311 0.8320181913861857 1.0156560662051735 0.9244966687736945 1.0928232963602753 1.0 16.62751653941411 -7.271744758393978 24.934756680078085 1.0019520721570547 0.880608461451627 0.5921805002121662 0.05271676222830937 534.7787097796835 1293938.110268793 0.021896377736425252 0.014943417453201761 5.348786235057993e-08 7.271744758393978 -0.12134361070542776 S(ph)SSPELVTHLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSPELVTHLK 11 0 Q07960;H0YE29;E9PNR6 Q07960 ARHGAP1 Rho GTPase-activating protein 1 1 S(0.333)S(0.333)S(0.333)PELVTHLK 128.54 0.00017269 26838000.0 58780.0 55698.0 64952.0 77310.0 64765.0 68222.0 69248.0 58620.0 57578.0 48785.0 True False 68730.29304208055 61227.32934474168 66500.70201183161 72978.57134240177 52074.76316944259 64644.31822203286 62688.32812789569 57081.28711302406 58419.96932312587 57629.33431815249 1.1926268775315596 1.0624333955815948 1.1539384030484066 1.266344166661916 0.9036155594294226 1.1217259228633973 1.0877850467925618 0.9904901347271714 1.0137193152467898 1.0 15.814515734664521 -6.2567428349663095 24.999770813148878 1.0276004529582365 1.160171445919664 0.5032926314917634 0.07218260661051432 389.3635776523023 2072587.61474628 0.02192686637555133 0.027337722507142337 5.536778694003136e-07 6.2567428349663095 0.13257099296142738 S(ph)SSPELVTHLK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSPELVTHLK 11 0 Q07960;H0YE29;E9PNR6 Q07960 ARHGAP1 Rho GTPase-activating protein 1 1 S(0.645)S(0.177)S(0.177)PELVTHLK 113.54 0.0008788 28880000.0 76990.0 94245.0 99148.0 83635.0 103500.0 103130.0 92885.0 92337.0 108250.0 80053.0 True False 75892.10848176305 94026.78149289553 90996.43416234796 89785.79689818101 97412.33348882922 98719.370307772 97694.13081020449 96627.31411279111 96057.74507696493 93890.05438608261 0.8083082811912035 1.0014562469657402 0.9691807588923542 0.9562865575620544 1.0375149330328721 1.0514358624378988 1.0405162873639335 1.0291538837058576 1.0230875432446616 1.0 16.518684723287862 -3.908618549754638 1.0115432858514872 1.0227756305282338 5.0985006492035305e-43 0.7926020569871159 0.03088611124482757 4.353292758842353 0.9722726367108651 0.010429002479042432 7.356873437305668 0.00012341883716770178 3.908618549754638 -1.0227756305282338 S(ph)SSPGKPQAVSSLNSSHSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSPGKPQAVSSLNSSHSR 19 1 Q9UHB7;Q9UHB7-2;Q9UHB7-3 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 S(0.468)S(0.468)S(0.064)PGKPQAVSSLNSSHSR;S(0.333)S(0.333)S(0.333)PGKPQAVSSLNSSHSR 59.342 0.0093446 41991000.0 46726.0 46480.0 132209.0 139636.0 193261.0 167223.0 159258.0 132706.0 147785.0 101280.0 True False 54635.788919432845 51094.227224381335 135361.36396542488 131812.64762602013 155392.894385697 158453.5315007329 144171.92931192846 129222.60811362944 149946.07604324812 119641.2622679614 0.4566634276815358 0.42706192040957597 1.131393646301182 1.101732338219555 1.2988235951377913 1.3244053806941904 1.2050351741443979 1.0800839581933583 1.2532973424119582 1.0 16.868355511154505 -5.280887740542163 4.920715987072982 1.1893135554592702 0.4329668475991583 0.9032209423530316 0.09590948141544203 0.046604293599608035 3.2953143066840975 0.02582476971173379 0.060969531103496975 5.2373579796162344e-06 5.280887740542163 -0.7563467078601118 down S(ph)SSPHDKNLPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSPHDKNLPQK 12 1 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 S(0.449)S(0.449)S(0.101)PHDKNLPQK 60.345 0.028477999999999996 3939800.0 14040.0 9062.1 19190.0 29424.0 30316.0 34591.0 20328.0 28314.0 39323.0 28347.0 True False 16416.694697359857 9961.725398667519 19647.56237848027 27775.468673895088 24375.797425226905 32776.98706602472 18402.384678024842 27570.7875011628 39898.02448319285 33486.08670527147 0.4902542014494485 0.29748849085728846 0.5867380847278072 0.8294629622852467 0.7279380729008744 0.9788240517475838 0.5495531574051586 0.823350537906316 1.191480653871448 1.0 15.031274167335715 -5.113899806167631 0.3415012455212863 0.999705031649445 3.431283934523346e-18 0.589178688311873 0.16478274612688415 4.0970388390797785 0.4569119125220642 0.17454574555705935 1.6659729768392821 7.693079028600501e-06 5.113899806167631 -0.999705031649445 S(ph)SSPIPLTPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSPIPLTPSK 11 0 Q8N5Y2;Q8N5Y2-3;Q8N5Y2-2;A0A3B3IT59;Q8N5Y2-6;Q8N5Y2-4;A0A3B3ITL5;A0A3B3ITF3;A0A3F2YNX2;A0A3B3IRN2 Q8N5Y2 MSL3 Male-specific lethal 3 homolog 1 S(0.333)S(0.333)S(0.333)PIPLTPSK 114.76 0.0014259000000000001 16241000.0 72418.0 76325.0 83438.0 102550.0 91214.0 93114.0 89343.0 91515.0 74944.0 66520.0 True False 84676.93707930262 83902.04158564782 85427.47836037731 96804.455971586 73341.27148517783 88230.9379221712 80879.78425269437 89112.82821815737 76039.91421988154 78579.54942796989 1.0775950956160918 1.067733808559908 1.0871464520000154 1.231929384633619 0.9333378979527779 1.122823159008417 1.029272690432426 1.1340460573630908 0.9676807104828679 1.0 16.261866275013432 -8.27386574227929 24.480494376893496 0.9838403301520507 1.0841299012875936 0.23957190248675697 0.07240436996081664 931.8127922540673 1835687.8497281012 0.06448499082373005 0.017178480192905885 5.3227278055038174e-09 8.27386574227929 0.10028957113554282 S(ph)SSPPILTKPTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSPPILTKPTLK 13 1 A0A3B3ITI3;A0A3B3IS53;A0A3F2YNX6;Q92794 A0A3B3ITI3 KAT6A Histone acetyltransferase KAT6A 1 S(0.353)S(0.353)S(0.294)PPILTKPTLK;S(0.486)S(0.486)S(0.028)PPILTKPTLK 69.729 0.014081 18326100.0 98253.0 116497.0 114267.0 117533.0 121185.0 100259.0 111031.0 93343.0 89527.0 80106.0 True False 114885.2923147934 128062.05225814875 116991.55864001058 110948.00705712712 97439.66918380154 95001.24154411767 100513.33988517208 90892.84515508357 90836.16300655607 94628.58368125303 1.2140654318759867 1.3533125750831592 1.2363236782036706 1.1724576522337526 1.029706515655115 1.0039381109635952 1.0621879349239893 0.9605220919426108 0.9599230958853685 1.0 16.529988412019243 -6.083957837779877 1.605957802301177 0.9958820393548473 1.2861369832989997 0.8933103693149023 0.042043384220628824 0.11064583345360998 0.5713468538167324 0.014567686621787743 0.022924752991393807 8.242181279553697e-07 6.083957837779877 0.2902549439441524 S(ph)SSPTQYGLTK ddPTM_PC-9_AZD4547_30min_R2 2 SSSPTQYGLTK 11 0 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 S(0.358)S(0.358)S(0.26)PT(0.023)QY(0.001)GLTK;S(0.996)S(0.004)SPTQYGLTK 206.74 5.3191e-06 371190000.0 318627.0 292851.0 373066.0 500565.0 449220.0 392604.0 342936.0 402724.0 325365.0 347940.0 True False 419943.7581466878 387509.3587365669 368118.90108300594 385167.4729021571 386853.5571016321 368054.40981599013 373456.6396449385 340492.259476874 342563.12965418777 335758.72650469287 1.2507307331022364 1.154130416119358 1.0963792510032075 1.1471555092903107 1.152177222998328 1.096187174783217 1.1122767933172952 1.0140980191980655 1.0202657521975078 1.0 18.357065370802673 -1.5228787452803385 0.13211703416122367 0.9462596711489996 1.855029886588014 0.7753780932050902 0.03493144777102062 41.62390196394624 0.37231995607570206 0.19463257943745238 7.062716253173259 0.029999999999999933 1.5228787452803385 0.9087702154390144 S(ph)SSPTQYGLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSPTQYGLTK 11 0 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 S(0.411)S(0.411)S(0.179)PTQYGLTK;S(0.869)S(0.04)S(0.086)PT(0.005)QYGLTK 87.641 0.010262 302890000.0 276360.0 263549.0 291172.0 343058.0 362641.0 326576.0 333821.0 283912.0 288016.0 221409.0 True False 323142.2896411947 289712.4029853371 298114.6447559596 323837.5724690427 291584.09929020086 309449.7796558092 302199.0582252518 276459.6108296296 292227.68912725995 261548.69902732075 1.2354956872006464 1.1076805354519252 1.1398054965083932 1.2381540174864925 1.1148367412056701 1.1831440217696698 1.1554217602653218 1.0570100782674943 1.1172974295572182 1.0 17.996720068342988 -8.385791108001797 0.6333455078850382 1.001802934122985 1.1726020293882975 0.5544146115581794 0.04685589950554005 0.576712660726258 0.5454699504309279 0.045910080469116155 0.02004613658077487 4.1134752823514195e-09 8.385791108001797 0.17079909526531245 S(ph)SSPTSSLTQPIEMPTLS(ph)SSPTEERPTVGPGQQDNPLLK ddPTM_PC-9_AZD4547_30min_R2 1 SSSPTSSLTQPIEMPTLSSSPTEERPTVGPGQQDNPLLK 39 1 Q7LBC6;Q7LBC6-2 Q7LBC6 KDM3B Lysine-specific demethylase 3B 2 S(0.288)S(0.288)S(0.288)PT(0.074)S(0.02)S(0.02)LT(0.022)QPIEMPT(0.017)LS(0.304)S(0.304)S(0.304)PT(0.069)EERPT(0.002)VGPGQQDNPLLK 83.917 1.7458e-11 3933700.0 18293.0 19572.0 32610.0 39796.0 34163.0 33648.0 26575.0 33566.0 26246.0 32870.0 True False 24109.793481962784 25898.266248679673 32177.570093004524 30621.647042070923 29420.057146304775 31543.985240823975 28940.123517403386 28379.145969946523 27633.309977729044 31719.231304849338 0.760100181818618 0.8164846745425468 1.0144498706084695 0.9653968832904657 0.9275148210103988 0.9944750847729853 0.9123841381672742 0.8946984148890086 0.8711847305550678 1.0 14.953070188229438 -5.091229800189718 5.0469216176993665 0.9437103225535608 0.7720374464866212 0.6712543609190369 0.04520546484435102 0.12150348058735395 4.934223653236249 0.01215786545056843 0.035380259266639534 8.105320638948595e-06 5.091229800189718 -0.1716728760669396 S(ph)SSPTSSLTQPIEMPTLS(ph)SSPTEERPTVGPGQQDNPLLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSPTSSLTQPIEMPTLSSSPTEERPTVGPGQQDNPLLK 39 1 Q7LBC6;Q7LBC6-2 Q7LBC6 KDM3B Lysine-specific demethylase 3B 2 S(0.237)S(0.237)S(0.238)PT(0.081)S(0.067)S(0.067)LT(0.075)QPIEMPT(0.071)LS(0.238)S(0.238)S(0.238)PT(0.21)EERPT(0.004)VGPGQQDNPLLK 66.031 9.4614e-06 4347900.0 6814.9 6573.7 6394.1 7428.7 10117.0 8235.4 8440.3 7166.1 7377.5 6344.1 True False 7968.52796958958 7226.293491930201 6546.559593759283 7012.49402317035 8134.646475492169 7803.521126406864 7640.773681519736 6977.997468110568 7485.381980641236 7494.235110132029 1.0632876941392349 0.9642469692684744 0.8735460654161342 0.9357184449270378 1.0854538663317779 1.0412698576612158 1.0195535060261973 0.9311153660867244 0.9988186747065322 1.0 12.871565523458136 -4.753484158698752 24.875170659729086 0.9823695417409468 1.0632878512579755 0.1482577247043243 0.05747518906234221 621.2541732646046 1942433.1271163493 0.015904806862677968 0.17040141521241772 1.7640701094255975e-05 4.753484158698752 0.08091830951702872 S(ph)SSPTSSLTQPIEMPTLSS(ph)SPTEERPTVGPGQQDNPLLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSPTSSLTQPIEMPTLSSSPTEERPTVGPGQQDNPLLK 39 1 Q7LBC6;Q7LBC6-2 Q7LBC6 KDM3B Lysine-specific demethylase 3B 2 S(0.288)S(0.288)S(0.288)PT(0.099)S(0.012)S(0.012)LT(0.013)QPIEMPT(0.172)LS(0.172)S(0.28)S(0.28)PT(0.088)EERPT(0.006)VGPGQQDNPLLK 67.899 7.2497e-06 3911700.0 8297.7 8198.8 8378.6 8981.5 10205.0 11190.0 10122.0 10092.0 9178.5 9150.2 True False 9702.336722954624 9012.722680018454 8578.377600017453 8478.295673415874 8205.403507205463 10603.176701130835 9163.170883066095 9827.095693357873 9312.718198483974 10809.05882705665 0.8976116124623414 0.833811974217246 0.7936285422505541 0.7843694635275242 0.7591228467242811 0.9809528165939423 0.8477306886450968 0.9091536877160128 0.8615660574603298 1.0 13.399953288870766 -6.75484719208868 24.99997350870942 0.9096933844317386 0.8120801870378972 0.4707098724746819 0.05575827058155604 154.63735976577627 586440.3364255775 0.0185810837398832 0.018170823180906636 1.7585422538693273e-07 6.75484719208868 -0.09761319739384144 S(ph)SSQIPEGFGLTSGGSNYSLAR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSQIPEGFGLTSGGSNYSLAR 22 0 A2RRE0;Q9Y4E6-2;Q9Y4E6 A2RRE0 WDR7 WD repeat-containing protein 7 1 S(0.676)S(0.124)S(0.199)QIPEGFGLTSGGSNYSLAR 96.37899999999999 0.001827 0.0 4033.2 5022.0 5150.7 4352.7 4840.9 6997.3 4088.2 4430.5 5627.2 6338.4 True False 3975.6858284017017 5010.371867550758 4727.229328276973 4672.812078181546 4556.167779575582 6698.041790502985 4299.866992283771 4636.357204335442 4993.405478957018 7433.983994612884 0.5347988146440354 0.6739820628052976 0.6358944721568691 0.6285744066126251 0.6128837219554492 0.9010029878133707 0.5784068132780101 0.6236705927394015 0.6716997887775307 1.0 12.85991986673888 -14.522878745280268 0.3303714222043708 4.491658748460749 0.6412499567175338 0.5671267800476467 0.09179220655277673 271.754556655702 2.3483761034221895 666.6283267915791 0.0781459403679449 3.00000000000048e-15 14.522878745280268 -3.850408791743215 S(ph)SSQLGSPDVSHLIR ddPTM_PC-9_AZD4547_30min_R2 2 SSSQLGSPDVSHLIR 15 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 S(0.74)S(0.228)S(0.032)QLGSPDVSHLIR;S(0.492)S(0.492)S(0.015)QLGSPDVSHLIR 212.34 3.3794e-14 9843500.0 13762.0 9619.099999999999 23016.0 28456.0 24614.0 20696.0 18474.7 26384.0 18504.6 19714.8 True False 18138.02973261748 12728.285963247214 22710.792801612755 21895.908840817418 21196.770968566725 19401.875848314692 20118.91250976379 22306.959044004918 19482.715378110366 19024.590852718084 0.9533992017508257 0.6690438738885518 1.1937598541504517 1.1509266617257685 1.114177494415776 1.0198314380854454 1.0575214292658157 1.1725329189309674 1.0240806506136677 1.0 14.215577806676333 -5.266998864103455 24.99973967800085 1.0969100479932776 0.8112215339316681 0.6080576698866998 0.08996217668755174 248.65343186102714 1118142.3521882389 0.0224096386721884 0.04886148172476288 5.407557372895253e-06 5.266998864103455 -0.28568851406160956 S(ph)SSQLGSPDVSHLIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSQLGSPDVSHLIR 15 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 S(0.479)S(0.479)S(0.042)QLGSPDVSHLIR;S(0.437)S(0.437)S(0.126)QLGSPDVSHLIR 147.64 2.6655e-05 7299500.0 21933.0 22318.8 27296.0 26212.0 30855.0 28384.0 26809.0 31628.0 29666.0 22916.0 True False 25645.823703503844 24534.462964189384 27946.840160656473 24743.4266204506 24809.184244470805 26895.493072823723 24269.45743964818 30797.798512636044 30099.809127441917 27070.48939704381 0.9473720008292298 0.906317673254501 1.0323729191134743 0.9140369151638856 0.9164660409567643 0.9935355315652625 0.8965282113554434 1.137689018507337 1.1119048749347293 1.0 14.724433349270996 -7.762581169274279 24.999999999988248 1.0935977269172688 0.945485263547702 0.6027686827497143 0.05163682577500172 18.61867937057632 407627.3027070739 0.025190164751916346 0.013166803914537248 1.7275030814575357e-08 7.762581169274279 -0.14811246336956674 S(ph)SSQLGSPDVSHLIR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSQLGSPDVSHLIR 15 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 S(0.774)S(0.217)S(0.009)QLGSPDVSHLIR;S(0.488)S(0.488)S(0.024)QLGSPDVSHLIR 174.15 4.0454e-05 8589400.0 23495.6 27922.0 28593.5 25722.5 22437.3 19685.7 20943.4 28516.9 25815.0 19894.3 True False 23160.54843543465 27857.348324522576 26242.652804101897 27614.218457744573 21117.582127429036 18843.78850060803 22027.74677515679 29841.899280061694 22907.44285599862 23333.003247511526 0.9926089749250231 1.1939032463595776 1.1247010307985401 1.183483247519354 0.9050520373831961 0.8076023605155811 0.944059645536888 1.278956633379132 0.9817614394941512 1.0 14.510084391605329 -6.254010819178545 24.9728993136821 0.9891457486782678 1.128763842245147 0.22910315147886806 0.12329526492222752 969.712603612167 3259923.188449741 0.04001553584589932 0.05061499608717531 5.571718684493002e-07 6.254010819178545 0.13961809356687915 S(ph)SSQPSPSDPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSQPSPSDPK 11 0 A0A0A0MT50;A0A087X1S4;A0A087WUP2;E7ESE9;J3KNW2;E7EUP4;B5MDK9;Q9H322;Q9NNX9;Q9H320;Q9H321-2;Q9H321 A0A0A0MT50 VCX3B;VCX;VCX3A;VCX2 Variable charge X-linked protein 2;Variable charge X-linked protein 3;Variable charge X-linked protein 1;Variable charge X-linked protein 3B 1 S(0.556)S(0.004)S(0.098)QPS(0.338)PS(0.003)DPK 99.788 0.004417 4176500.0 37073.0 35455.0 35253.0 44815.0 44518.0 35432.0 41817.0 39851.0 32526.0 34671.0 True False 43348.726674873375 38974.738086068 36093.56521774701 42304.160842190315 35795.01747513697 33573.883545528835 37855.791031137574 38804.95347562473 33001.63121685349 40956.577844515 1.0584069508795335 0.9516111974498764 0.881264185566733 1.0329027245096305 0.8739748133017106 0.8197433797566446 0.9242908715384117 0.9474657190095677 0.8057712082815813 1.0 15.321807554530816 -1.5228788757644858 0.7963814084349312 0.9022684586436459 38.08022741832643 0.29779471286639814 0.06801731765943507 613.3767099117963 2.1670556696669228 0.024107466999738515 41126.488448612174 0.029999990986475718 1.5228788757644858 37.17795895968278 S(ph)SSQPSPSDPK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSQPSPSDPK 11 0 A0A0A0MT50;A0A087X1S4;A0A087WUP2;E7ESE9;J3KNW2;E7EUP4;B5MDK9;Q9H322;Q9NNX9;Q9H320;Q9H321-2;Q9H321 A0A0A0MT50 VCX3B;VCX;VCX3A;VCX2 Variable charge X-linked protein 2;Variable charge X-linked protein 3;Variable charge X-linked protein 1;Variable charge X-linked protein 3B 1 S(0.325)S(0.038)S(0.325)QPS(0.311)PS(0.001)DPK 104.59 0.0060925 0.0 14308.0 14036.0 14559.0 13606.0 17095.0 13916.0 13784.0 14753.0 11546.0 12563.0 True False 14103.965296234148 14003.500504369276 13362.015219365214 14606.630628285448 16089.50571006313 13320.84511978042 14497.668074370014 15438.478238474383 10245.567895229902 14734.497810854737 0.9572070577012756 0.950388719325952 0.9068524350739371 0.9913219178413335 1.09196159357465 0.9040583052628441 0.9839268538687316 1.0477777007846871 0.695345577891505 1.0 13.846910270134483 -10.61160855280033 4.62140740478299 1.0000027790626511 0.9547884708731014 0.019331498244542167 0.10092295869275734 2.7693485626004414e-06 5.459534053235189e-07 0.09364500110336178 0.02271085283572493 2.4456339084151305e-11 10.61160855280033 -0.045214308189549746 S(ph)SSRNEHGIK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSRNEHGIK 10 1 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 S(0.849)S(0.149)S(0.002)RNEHGIK 69.846 0.017608000000000002 951100.0 3034.7 4217.8 7306.8 5091.5 6969.2 5777.4 7876.1 8106.3 9088.4 6940.2 True False 2991.4246215041794 4208.033943240859 6706.063109063652 5465.945894746094 6559.285357974378 5530.314069777191 8283.88591994673 8482.94829150308 8064.768686905199 8139.8043227647895 0.36750571670844584 0.5169699143101202 0.8238604815485111 0.6715082670303695 0.8058283833224178 0.6794160953366443 1.0177008674249064 1.0421562921087195 0.9907816413166424 1.0 12.990778397830509 -4.948209742236722 0.3393792716972865 1.0501923312699435 2.4117288013337617e-14 0.7981669223724999 0.09848210823338961 2.8554485998899377 0.28877535593662246 0.1065015727085067 1.2283506286336514 1.1266532083320292e-05 4.948209742236722 -1.0501923312699193 down S(ph)SSSELLLTGPGAEEDPLPLIVQDQYVQEAR ddPTM_PC-9_AZD4547_30min_R2 1 SSSSELLLTGPGAEEDPLPLIVQDQYVQEAR 31 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 S(0.302)S(0.302)S(0.094)S(0.302)ELLLTGPGAEEDPLPLIVQDQYVQEAR 123.91 1.1059999999999999e-10 0.0 768.76 926.51 2855.2 3069.7 2521.7 4079.6 2930.0 3055.0 2823.8 2137.3 True False 1013.2096887986501 1225.9862386094517 2817.33818244546 2362.0280913922284 2171.605482710439 3824.5019670846855 3190.764323837891 2582.919946916123 2973.060303098042 2062.4737775434896 0.4912594282800696 0.5944251277073996 1.3659995162707241 1.1452403017727202 1.0529130146308725 1.8543275598101714 1.5470569170766633 1.2523407449051358 1.441502110460336 1.0 11.010160061597045 -5.237459570164155 4.750064618556553 1.3533141942329672 0.5205309025153739 0.6367673134555676 0.23837657104562127 0.11891622725616671 7.276614171523059 0.06468192412667718 0.17093356144032607 5.7881586962633205e-06 5.237459570164155 -0.8327832917175932 S(ph)SSSELLLTGPGAEEDPLPLIVQDQYVQEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSELLLTGPGAEEDPLPLIVQDQYVQEAR 31 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 S(0.333)S(0.333)S(0.066)S(0.268)ELLLTGPGAEEDPLPLIVQDQYVQEAR 155.74 7.5553e-16 1083700.0 0.0 0.0 771.9 747.87 1645.9 509.37 841.99 980.64 676.33 491.52 True False 0.0 0.0 790.3050234470512 705.9692685272537 1323.397710192011 482.6577405053629 762.2306117202944 954.8992390739663 686.2200467593473 580.6286851298206 0.0 0.0 1.361119496310021 1.2158704635293873 2.279249620428445 0.8312674741473498 1.3127677485480589 1.644595355912297 1.1818569497749114 1.0 9.181472037785229 -5.263621864288022 7.591828349117504 1.3855304748367874 3.217267128300594e-17 0.6764981542603333 0.37383562729126235 0.06050498971954227 32.25324511731602 0.0948530043213699 0.22108774580229143 5.449769521223441e-06 5.263621864288022 -1.3855304748367874 S(ph)SSSERPEPQQK ddPTM_PC-9_AZD4547_30min_R2 1 SSSSERPEPQQK 12 1 P78362;C9J2M4 P78362 SRPK2 SRSF protein kinase 2;SRSF protein kinase 2 N-terminal;SRSF protein kinase 2 C-terminal 1 S(0.344)S(0.319)S(0.319)S(0.017)ERPEPQQK 67.115 0.017765 17019000.0 21399.0 17598.0 27271.0 36049.0 32792.0 25177.0 23504.0 26793.0 22466.0 26576.0 True False 28203.43687314936 23286.20935235359 26909.368721445146 27738.460001498013 28239.39683112215 23602.67820994486 25595.81046671871 22652.75749188991 23653.506894751972 25645.58232910485 1.0997386025873794 0.9080008031607987 1.0492789119046846 1.0816077266460813 1.1011407917641087 0.9203408956387189 0.9980592422606192 0.883300570101759 0.922322862129276 1.0 14.646422710224142 -6.775353053464327 24.998484254467076 0.940839390902841 1.0421215570634312 0.4143145356763448 0.061032472454465025 252.27537371932624 453256.51824575436 0.02195818685209264 0.019464993277045865 1.6774398130775384e-07 6.775353053464327 0.10128216616059027 S(ph)SSSQTLTQFDSNIAPADPDTAIVHPVPIR ddPTM_PC-9_AZD4547_30min_R2 1 SSSSQTLTQFDSNIAPADPDTAIVHPVPIR 30 0 Q96D71;Q96D71-3;H0YE73 Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 S(0.567)S(0.14)S(0.234)S(0.058)QTLTQFDSNIAPADPDTAIVHPVPIR 189.33 3.1291999999999994e-29 6845900.0 6594.6 2287.2 3426.5 10854.0 11040.0 8813.4 7958.7 12061.0 9331.7 10007.0 True False 8691.545623798813 3026.4926713662426 3381.0623711646713 8351.777992628346 9507.286564271424 8262.296704751483 8667.008881955157 10197.24958420797 9824.954610956875 9656.657975893744 0.9000573123223194 0.31340994771911596 0.3501275886134661 0.8648725069767598 0.9845317694801657 0.85560622788722 0.8975163978667274 1.0559812317743595 1.017428041407623 1.0 13.237308265044414 -5.882682940456848 5.452021021666329 0.9586608645802681 0.5031118620493632 0.6163809973769229 0.15755535386862346 0.1318353129599396 5.761130594331308 0.04487738090620684 0.06769661746475679 1.3101380488441508e-06 5.882682940456848 -0.4555490025309049 S(ph)SSSRGSSYSSIPK ddPTM_PC-9_AZD4547_30min_R2 1 SSSSRGSSYSSIPK 14 1 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 1 S(0.25)S(0.25)S(0.25)S(0.194)RGS(0.047)S(0.008)YSSIPK 91.65700000000001 0.0021011 7196700.0 19284.0 27036.0 33501.0 51704.0 47970.0 41703.0 32906.0 44068.0 31543.0 44383.0 True False 25415.91086788226 35774.85828220433 33056.75485083545 39784.44161883694 41310.19352247283 39095.30481746561 35834.57025263127 37258.30318189845 33210.29858368919 42829.16467913379 0.5934253226345271 0.8352919920391001 0.7718281479101687 0.9289100526917298 0.9645341867383886 0.9128196898155404 0.8366861815096229 0.86992831779534 0.7754131754026276 1.0 15.386305919374175 -4.23746934740383 1.1501886907832697 0.8874729863656547 8.375077970646297e-18 0.6141494244112928 0.06919107071138232 3.3773868010510633 1.575319016384508 0.021251758854826944 4.896235352573508 5.78802838933983e-05 4.23746934740383 -0.8874729863656547 S(ph)SSSSSQPEHSAMLVSTAASPSLIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSSSQPEHSAMLVSTAASPSLIK 25 0 P42166 P42166 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin 1 S(0.285)S(0.285)S(0.285)S(0.055)S(0.055)S(0.017)QPEHS(0.017)AMLVSTAASPSLIK 61.111999999999995 0.014712000000000001 0.0 4028.7 4034.3 6248.1 5649.3 6524.4 6454.5 5272.9 6155.0 5452.4 3416.8 True False 4710.679339547982 4434.79864224014 6397.078400051205 5332.788036277718 5245.990655797287 6116.014657502141 4773.412739509901 5993.437771761564 5532.131035072616 4036.2387926260803 1.1670962947370844 1.0987453592543137 1.5849107866804635 1.3212270904338812 1.2997225697798993 1.5152757236949563 1.1826388340131375 1.4849066370183912 1.3706153969828108 1.0 11.978795814593576 -5.219054560597615 24.98740180698989 1.3600594486385202 1.1329206559979936 0.21296071134680516 0.16092042032398612 636.4329782329125 375198.4999251001 0.03764175857304743 0.09958951056306019 6.038727598230392e-06 5.219054560597615 -0.2271387926405266 S(ph)SSSTGSEVGGQSTGSNHK ddPTM_PC-9_AZD4547_30min_R2 2 SSSSTGSEVGGQSTGSNHK 19 0 Q9UPQ9-1;Q9UPQ9;H0Y720 Q9UPQ9-1 TNRC6B Trinucleotide repeat-containing gene 6B protein 1 S(0.353)S(0.353)S(0.078)S(0.078)T(0.078)GS(0.061)EVGGQSTGSNHK;S(0.434)S(0.434)S(0.083)S(0.016)T(0.016)GS(0.016)EVGGQSTGSNHK 132.65 1.5557e-05 6852500.0 4543.1 6276.6 16877.6 40287.0 25310.0 17482.5 9387.8 29555.0 12829.7 24298.0 True False 5987.711297649655 8305.388204397237 16653.791996372067 30999.454577945326 21796.14338240124 16389.316511314344 10223.296013421615 24987.95385633584 13507.851749648333 23447.33441573559 0.2553685289544589 0.35421460099206253 0.7102637639353857 1.3220886446325208 0.9295787314644077 0.6989842094935711 0.4360110122607679 1.0657055259793768 0.5760932782441643 1.0 14.517136300422985 -5.298711057065527 3.7294107695156797 0.8519367542523559 0.2884770440369685 0.4541822680734635 0.23982096491497565 0.20385325108792055 6.047376392891002 0.06655563154618348 0.16646192820098815 5.026769171351528e-06 5.298711057065527 -0.5634597102153874 S(ph)SSSTGSEVGGQSTGSNHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSTGSEVGGQSTGSNHK 19 0 Q9UPQ9-1;Q9UPQ9;H0Y720 Q9UPQ9-1 TNRC6B Trinucleotide repeat-containing gene 6B protein 1 S(0.469)S(0.469)S(0.023)S(0.005)T(0.005)GS(0.023)EVGGQS(0.006)TGSNHK 114.19 0.0003587 0.0 3108.0 3183.3 6446.1 5512.7 7495.7 6228.7 5060.3 5052.3 5171.3 3795.4 True False 3634.1230142018862 3499.3169863032085 6599.799470970385 5203.84129141454 6026.971393332677 5902.05600700032 4580.951750600608 4919.68247835434 5246.920479361571 4483.475975630133 0.8105592700741808 0.7804919676883949 1.4720273972345335 1.1606711666795901 1.3442631177443998 1.3164018362272616 1.021741116825495 1.0972920352635323 1.1702796017824406 1.0 12.130401951846752 -5.2357284722364055 24.64186903928504 1.2031570739111948 0.7955254243034896 0.5718028990471918 0.13919645627648375 448.90239944600916 430235.50866966194 0.035847051133168245 0.09476073154814371 5.811276341326128e-06 5.2357284722364055 -0.40763164960770515 S(ph)SSTEPPPPVR ddPTM_PC-9_AZD4547_30min_R2 2 SSSTEPPPPVR 11 0 Q8N684-2;Q8N684;Q8N684-3;F5H669;F5H6M0;F5H047;F5H5B7;F5H1W4;F5H2K8;F5H6P5;F5H6A8;F5GXA3;C9JM38;C9J286;C9J323;J3QT54 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 1 S(0.898)S(0.067)S(0.035)TEPPPPVR;S(0.46)S(0.46)S(0.078)T(0.001)EPPPPVR 177.57 6.1072e-05 47469000.0 122964.0 154326.0 160535.0 145279.0 152495.0 183717.0 161138.0 190393.0 162015.0 155496.0 True False 162063.99418991292 204208.86149058538 158406.2010082942 111787.1710881752 131323.70150530504 172229.1469474697 175478.9698343314 160972.1366458924 170578.78213982226 150052.13236929852 1.0800512570594571 1.3609194235773994 1.0556744413230676 0.7449888870159599 0.8751871728293719 1.147795397692787 1.169453356400521 1.07277473571464 1.13679678819895 1.0 17.195104295450676 -5.494158964751522 22.645944816409436 1.019494794848474 1.2174385390967224 0.2443685360418033 0.13840786983832787 322.9385303022718 254638.80886532014 0.0397368874695795 0.08234522041655189 3.205095948928873e-06 5.494158964751522 0.19794374424824834 S(ph)SSTGNLLDKDDLAIPPPDYGAASR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSTGNLLDKDDLAIPPPDYGAASR 25 1 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 S(0.429)S(0.132)S(0.429)T(0.009)GNLLDKDDLAIPPPDYGAASR 106.18 2.8392e-07 55837000.0 349830.0 274360.0 299920.0 286570.0 296360.0 261900.0 213130.0 212670.0 245030.0 212020.0 True False 344841.36004903534 273724.7362766275 275261.73532468034 307645.3137694956 278928.6874661779 250699.14751871873 224164.82854690056 222551.4245900056 217432.14111971113 248667.37450110834 1.3867575541056687 1.10076658357692 1.1069475273019922 1.2371760243446186 1.1216939416591407 1.0081706457137236 0.9014645728923375 0.8949763716953294 0.8743894994505683 1.0 17.92385771084946 -6.8234130074291475 1.9110669504902897 0.9079818427507307 1.194199111761572 0.7227117258712848 0.08137913821108168 0.18093672231242022 1.3601021598535212 0.03378376751270413 0.029620151454564356 1.5017131804880492e-07 6.8234130074291475 0.2862172690108413 S(ph)SSVGSSSSYPISPAVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 S(0.442)S(0.04)S(0.442)VGS(0.067)S(0.006)S(0.002)SYPISPAVSR;S(0.333)S(0.333)S(0.333)VGS(0.002)SSSYPISPAVSR;S(0.48)S(0.039)S(0.48)VGSSSSYPISPAVSR 281.68 1.4774999999999997e-92 1085432000.0 66882.0 80405.0 76439.0 83219.0 103311.0 92544.0 107714.0 111495.0 99178.0 86010.0 True False 78203.80162028631 88387.07702186712 78261.59565652173 78556.50922963828 83067.95117421882 87690.82972559886 97510.55013817227 108568.37438871768 100628.29062365807 101602.93214521487 0.7697002435767738 0.8699264396773596 0.7702690661000532 0.7731716749804253 0.8175743496801339 0.8630738097230078 0.9597218119532849 1.068555523905034 0.9904073484792367 1.0 16.632582511687843 -7.230729982791566 1.9378819548518138 1.023001174935447 0.8006760679050545 0.8874646667235209 0.03481769920929228 0.10362704984672408 0.7605942349799539 0.01743767244173925 0.011296713988974758 5.878547303220381e-08 7.230729982791566 -0.22232510703039254 S(ph)SSVGSSSSYPISPAVSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 S(0.482)S(0.036)S(0.482)VGSSSSYPISPAVSR 320.0 6.931899999999997e-157 1388400000.0 54980.0 43873.0 58413.0 50033.0 65029.0 71553.0 74217.0 57092.0 75573.0 59925.0 True False 54195.97511790284 43771.41476404906 53610.508620700646 53712.593725195184 61204.12207193309 68492.8449881897 78059.59311343005 59744.70274459293 67061.17292102978 70282.95640495667 0.7711112037694632 0.6227884682574637 0.7627810690234396 0.764233556364842 0.8708245242173208 0.9745299357293296 1.1106475468058845 0.8500596133201287 0.954159818415099 1.0 16.10088725816185 -6.3439054842588884 1.7510595958808477 0.9771058996142935 0.710352564597723 0.7347339951397344 0.07038510588591392 0.18947674196911374 1.1504926977238994 0.026229878030787954 0.03273859802330208 4.5299615497301493e-07 6.3439054842588884 -0.2667533350165705 S(ph)SSVLSLEGSEK ddPTM_PC-9_AZD4547_30min_R2 1 SSSVLSLEGSEK 12 0 A1L390-3;A1L390;G3V311;A1L390-2;A0A0U1RR71 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 S(0.333)S(0.333)S(0.333)VLSLEGSEK 74.78 0.020462 7601400.0 50898.0 55432.0 61865.0 81208.0 72530.0 72168.0 57206.0 85529.0 69585.0 70063.0 True False 67082.50525583231 73349.3099681591 61044.62967812709 62486.750251092955 62460.461458931684 67655.32355146755 62297.223177293636 72312.4583108966 73263.12103940702 67610.11569551754 0.9921962795913362 1.0848866210862298 0.9028919570710668 0.9242219098174941 0.9238330805440809 1.0006686552076556 0.9214186743570957 1.069550873667427 1.0836118276937703 1.0 16.044951495464467 -7.773692952575765 24.992404987583505 1.0574360503443985 0.9648789899063639 0.34606712577585597 0.05443231717917067 261.52930345540045 533407.1772947948 0.030818916937158852 0.014976059321671571 1.683864137023913e-08 7.773692952575765 -0.09255706043803458 S(ph)SSVLSLEGSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSVLSLEGSEK 12 0 A1L390-3;A1L390;G3V311;A1L390-2;A0A0U1RR71 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 S(0.877)S(0.078)S(0.044)VLSLEGSEK 179.59 0.0007814 12000000.0 39296.0 47703.0 43999.0 62478.0 58817.0 52342.0 55247.0 54623.0 44376.0 45592.0 True False 45948.03666862199 52438.638581855914 45048.10302713673 58977.56021640893 47292.23107136733 49597.09337717518 50013.60420635767 53189.204127852514 45024.91504885602 53857.46869392656 0.8531414079214513 0.9736558336944149 0.8364318658039112 1.0950674371939013 0.8780997736846926 0.9208953666024817 0.9286289426372102 0.987591979677474 0.8360013223928852 1.0 15.716858804180388 -4.745339830090613 24.170784784349745 0.9379947753273608 0.853141041730892 0.1053470242630099 0.07545414226054283 1424.305012686926 2138176.306372424 0.01744356422773308 0.423831360906439 1.7974638713314065e-05 4.745339830090613 -0.08485373359646875 S(ph)SSVPHPFQVTLLR ddPTM_PC-9_AZD4547_30min_R2 1 SSSVPHPFQVTLLR 14 0 Q5VV41;Q5VV41-2 Q5VV41 ARHGEF16 Rho guanine nucleotide exchange factor 16 1 S(0.995)S(0.004)S(0.001)VPHPFQVTLLR 170.42 0.00026713 45493000.0 25791.0 24004.0 37938.0 55530.0 49098.0 44623.0 34408.0 56160.0 43032.0 38165.0 True False 33992.001513874246 31762.82357619592 37434.91733175114 42728.41642994772 42281.59019317015 41832.71675586329 37470.24534287172 47481.762428415524 45306.58366843085 36828.85496652191 0.9229719888053426 0.8624439615369225 1.0164561826801335 1.1601885659705853 1.1480560617918987 1.1358679707498367 1.0174154308335908 1.289254375993424 1.2301925680180756 1.0 15.168548923140614 -5.538268381040155 3.0126958584883146 1.1473004720508049 0.8942096004362209 0.5895548567097466 0.08275231314997039 0.17011448477886276 3.1385909163662187 0.023522772682022495 0.04966982373608402 2.8955536688714287e-06 5.538268381040155 -0.253090871614584 S(ph)SSVPHPFQVTLLR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSVPHPFQVTLLR 14 0 Q5VV41;Q5VV41-2 Q5VV41 ARHGEF16 Rho guanine nucleotide exchange factor 16 1 S(0.893)S(0.099)S(0.007)VPHPFQVTLLR;S(0.812)S(0.157)S(0.031)VPHPFQVTLLR 174.24 0.00013295 54632000.0 87166.0 79407.0 94404.0 80006.0 99953.0 126055.0 103818.0 103147.0 128349.0 70030.0 True False 85922.99685571347 79223.13797025156 86642.46752997817 85889.90813219217 94073.96105515886 120663.92149855716 109193.18805462476 107939.58617663635 113892.98404511207 82134.59219089031 1.0461243498478505 0.9645526428880027 1.0548840046421735 1.0457214900705183 1.14536346435519 1.4690999039493642 1.3294421405398487 1.314179364594302 1.3866628056107173 1.0 16.32570234176515 -6.544826602174586 5.011682335768951 1.321847825616775 1.0316239517253794 0.544921972742874 0.11646417411848861 0.12652221692167384 8.595278075080916 0.03649910632116807 0.03761958057726236 2.852156801589657e-07 6.544826602174586 -0.2902238738913956 S(ph)STDSLPGPISR ddPTM_PC-9_AZD4547_30min_R2 1 SSTDSLPGPISR 12 0 Q9HCD5 Q9HCD5 NCOA5 Nuclear receptor coactivator 5 1 S(0.988)S(0.012)TDSLPGPISR 132.14 9.581100000000001e-05 9851000.0 27778.0 31774.0 40681.0 52609.0 60036.0 52417.0 36764.0 56676.0 47743.0 48274.0 True False 36610.82618170675 42044.32412556443 40141.54335950681 40480.80785094759 51701.03769679341 49139.35670376459 40035.92477869498 47918.02648491596 50266.597510733714 46583.94195346201 0.7859108664157589 0.9025497277058966 0.8617034470721425 0.8689863105915009 1.1098467739901328 1.0548561294545549 0.8594361726341538 1.0286382919845365 1.0790541848294146 1.0 15.507545105746672 -6.165175395545263 7.6456428060925266 1.0167317569937324 0.8574380962322115 0.5906379806225411 0.06812229879704862 0.22746273466119607 16.029692114242128 0.021058893052485247 0.027257146043665137 6.836354963243483e-07 6.165175395545263 -0.15929366076152096 S(ph)STDSLPGPISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTDSLPGPISR 12 0 Q9HCD5 Q9HCD5 NCOA5 Nuclear receptor coactivator 5 1 S(0.868)S(0.128)T(0.004)DSLPGPISR 86.803 0.0089236 7142000.0 18174.0 24125.0 25361.0 32543.0 36509.0 25780.0 30908.0 27143.0 24495.0 22181.0 True False 21250.499247138043 26519.97056342942 25965.7024221281 30719.721215829508 29355.32353204939 24428.05141690374 27980.17048545809 26430.52501038572 24853.1930350128 26202.239715300624 0.8110184273571451 1.012126095004896 0.9909726307467372 1.1724082196641736 1.1203364235656368 0.9322886776980039 1.0678541525257192 1.0087124344165048 0.9485140699823436 1.0 14.677402515283697 -4.663895485483575 2.4884364762145545 1.0360358011855635 0.709268068022426 0.46138582548872253 0.07025996047381418 0.82705127438088 4.70263114840594 0.019110127750837133 0.6562741336272084 2.1682258333212444e-05 4.663895485483575 -0.32676773316313745 S(ph)STDSLPGPISR ddPTM_PC-9_Lapatinib_30min_R1 1 SSTDSLPGPISR 12 0 Q9HCD5 Q9HCD5 NCOA5 Nuclear receptor coactivator 5 1 S(0.472)S(0.055)T(0.472)DSLPGPISR 116.71 0.00066409 7857300.0 37692.0 33778.0 33427.0 35123.0 32555.0 35228.0 34329.0 42253.0 35317.0 29517.0 True False 37154.50516813376 33699.789116314125 30678.761091951463 37706.0625868933 30640.17890559261 33721.380560478894 36106.38764691298 44216.22863216015 31339.22755550273 34618.97412106975 1.0732410798250904 0.9734485198336311 0.8861834260212755 1.0891733086898348 0.8850689450946043 0.9740722079905724 1.0429652687177107 1.2772252718271433 0.9052615899565059 1.0 15.079275352885595 -7.3937959256321015 4.842363248664978 1.083955982133832 0.9767799809804656 0.09428389651128832 0.10741670410318299 0.40058324582759713 14.035301170213609 0.044492898699898205 0.02927448006459468 4.038351099419807e-08 7.3937959256321015 -0.10717600115336645 S(ph)STETCYSAIPK ddPTM_PC-9_AZD4547_30min_R2 1 SSTETCYSAIPK 12 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;A0A0A0MT44 O75369-2 FLNB Filamin-B 1 S(0.986)S(0.014)TETCYSAIPK 151.7 0.00019099999999999998 4952400.0 20096.0 20749.0 24288.0 21854.0 29915.0 25295.0 23161.0 26734.0 25938.0 19477.0 True False 26486.10997723305 27455.708481190195 23965.92525050272 16815.897940934206 25761.818620487287 23713.29965129109 25222.28413119775 22602.874586204798 27309.02972652351 18795.116158337405 1.4092017178347664 1.460789507757897 1.2751145057367244 0.8946950792573193 1.3706655709632043 1.2616734821706332 1.3419594706792641 1.2025929712692036 1.452985419002552 1.0 14.1980702111602 -5.338263672234973 5.334815673128794 1.2293758094207612 1.434336563274347 0.2217536170985337 0.15851676888623617 0.3124126278085527 15.690918826717748 0.04137881205903263 0.08953226311159698 4.589193055910151e-06 5.338263672234973 0.2049607538535858 S(ph)STETCYSAIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSTETCYSAIPK 12 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;A0A0A0MT44 O75369-2 FLNB Filamin-B 1 S(0.656)S(0.163)T(0.028)ET(0.149)CYS(0.003)AIPK;S(0.815)S(0.184)T(0.001)ETCYSAIPK 158.01 9.329000000000001e-12 4501300.0 26868.9 33769.0 31444.0 30894.0 45384.0 28647.0 38642.0 29049.0 32078.0 24193.0 True False 31417.27408503506 37121.363148453835 32193.74421203406 29163.109339699404 36491.330991769966 27144.7008898387 34981.550016147004 28286.49452995967 32547.080064386217 28578.999388317374 1.0993132984872076 1.2989035285688988 1.126482553661215 1.0204384325513092 1.2768582446132464 0.9498128510732607 1.2240299088444253 0.9897650420022306 1.1388460324363536 1.0 14.802667785039041 -1.522878951221255 0.07228586345050417 0.879213498630711 1.683897331849348 0.14579048532812477 0.10854341941915158 415.44190490722514 2.2198774660111433 4.177925877002936 33.84629021333581 0.029999985774108773 1.522878951221255 0.804683833218637 S(ph)STETCYSAIPK ddPTM_PC-9_Lapatinib_30min_R1 2 SSTETCYSAIPK 12 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;A0A0A0MT44 O75369-2 FLNB Filamin-B 1 S(0.991)S(0.009)TETCYSAIPK;S(0.925)S(0.075)TETCYSAIPK 228.61 1.2805e-15 9689500.0 47787.0 78318.0 79369.0 73099.0 76803.0 77053.0 80167.0 79784.0 82810.0 70520.0 True False 47105.54861693745 78136.65948284372 72843.58719319986 78474.94431111559 72285.5985405076 73757.62280931596 84317.6549998564 83491.05590581178 73483.06577204126 82709.28803800642 0.5695315451789598 0.9447144490826533 0.8807183439872788 0.9488044955127038 0.8739719595614348 0.8917695286582928 1.019446025954315 1.0094519960980213 0.8884499856687734 1.0 16.335761728945535 -4.760745761466032 24.975204861710022 0.9373794822143641 0.5695311163696084 0.8163082423799395 0.05266915083319308 7.07572702296903 254593.92615374763 0.013612471476975493 0.07909143701434235 1.734819273917019e-05 4.760745761466032 -0.36784836584475566 S(ph)STGPEPPAPTPLLAER ddPTM_PC-9_AZD4547_30min_R2 1 SSTGPEPPAPTPLLAER 17 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.499)S(0.499)T(0.002)GPEPPAPTPLLAER 138.81 7.3241e-05 1937100.0 5301.3 6878.5 6654.7 7422.9 5345.7 7876.3 6082.5 10632.0 6118.9 5603.6 True False 6987.003126109944 9101.840608601222 6566.454329896262 5711.665087661783 4603.541828498707 7383.793715891044 6623.830716636165 8989.068699054735 6442.33256201807 5407.419669603099 1.2921140863887832 1.6832132818848313 1.2143415401635056 1.0562644360246254 0.8513379966376097 1.3654930016617353 1.2249522177594088 1.6623582500143783 1.1913875666489437 1.0 12.40072461292589 -14.522878742247679 0.024213100092741212 1.4392789994245436e-06 2.094204632403634 0.07216225613472771 0.24310258148084105 9116.566001979612 16.614629489426992 1031.239552975346 495.8684512384716 3.0000000209488646e-15 14.522878742247679 2.0942031931246343 S(ph)STGPEPPAPTPLLAER ddPTM_PC-9_Lapatinib_30min_R1 1 SSTGPEPPAPTPLLAER 17 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.638)S(0.36)T(0.002)GPEPPAPTPLLAER 87.669 0.0028561999999999997 2326900.0 7133.5 6060.0 3535.4 6351.6 7622.0 6875.3 7024.0 7351.5 6614.2 6352.5 True False 7031.774981876311 6045.96844232529 3244.733059038656 6818.717852316467 7173.6889454285565 6581.259446107096 7387.668351304047 7693.077527970207 5869.239145386253 7450.521160825821 0.9437963908952786 0.8114826213922397 0.435504173332085 0.9152001189082825 0.962843912604017 0.8833287368822967 0.9915639714101815 1.0325556242185747 0.7877622274594952 1.0 12.863125629678711 -5.967244206328787 24.999993579250678 0.9436209438793614 0.7278779167827802 0.337701656574794 0.1344529885972145 213.56908255945842 162999.63583312512 0.03806568457232163 0.056460180778775765 1.0783401947165876e-06 5.967244206328787 -0.2157430270965811 S(ph)STIQDQK ddPTM_PC-9_AZD4547_30min_R2 1 SSTIQDQK 8 0 Q9Y6W5;Q9Y6W5-2 Q9Y6W5 WASF2 Wiskott-Aldrich syndrome protein family member 2 1 S(0.499)S(0.499)T(0.002)IQDQK 87.181 0.031052999999999997 0.0 28280.0 23831.0 23655.0 28441.0 24120.0 23898.0 22336.0 25034.0 37913.0 38298.0 True False 37272.451739458105 31533.904709395323 23341.319244097565 21884.36685906974 20771.354341506052 22403.654282132993 24323.860729434527 21165.570524091072 39917.00377907647 36957.19867700395 1.0085302207347853 0.8532547335363059 0.6315770696825391 0.5921543743164428 0.5620381166614424 0.6062054236830813 0.6581629993663366 0.5727049473925907 1.0800873769665398 1.0 15.173567785438706 -8.267842413073858 24.982511257884415 1.0400437499613697 0.6785758775789712 0.5233852904679859 0.13517064366505488 462.6029919427679 1804895.8789639506 0.13054600993247942 0.036917657486839665 5.3970642340844785e-09 8.267842413073858 -0.3614678723823985 S(ph)STIQDQK ddPTM_PC-9_Lapatinib_30min_R1 1 SSTIQDQK 8 0 Q9Y6W5;Q9Y6W5-2 Q9Y6W5 WASF2 Wiskott-Aldrich syndrome protein family member 2 1 S(0.639)S(0.354)T(0.007)IQDQK 85.963 0.012832 3176500.0 22338.0 38510.0 24325.0 30339.0 35741.0 23173.0 43625.0 36093.0 31738.0 25244.0 True False 22019.4560237125 38420.83246104736 22325.092397215383 32570.231267937103 33638.78464950959 22181.94480890139 45883.68904123565 37770.01254397454 28163.332224043545 29607.391764484368 0.7437148195582024 1.2976770384460268 0.754037794845391 1.1000709392783061 1.1361617030332638 0.7492029350423838 1.5497376265435026 1.2756953683870818 0.9512263845485691 1.0 14.853669782790918 -7.245822854374888 24.999217964134484 1.2171395027919707 0.9832065277435356 0.18798524170081843 0.23075664551288994 1337.1827279136144 2140589.1835195757 0.08526951620376161 0.065809293634745 5.6777615002921e-08 7.245822854374888 -0.23393297504843513 S(ph)STPEEVK ddPTM_PC-9_AZD4547_30min_R2 1 SSTPEEVK 8 0 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 1 S(0.844)S(0.145)T(0.01)PEEVK 96.665 0.0060501999999999995 6873200.0 38201.0 69793.0 51865.0 59567.0 63377.0 48946.0 43152.0 54213.0 56405.0 39520.0 True False 50348.12336983869 92352.22237349788 51177.236212011005 45834.74845097592 54578.197516651264 45885.3988824706 46992.44440349921 45835.62654080649 59386.45314691028 38136.4168289518 1.3202111670757752 2.421628198257666 1.3419518787396691 1.201863002928472 1.4311307158573288 1.2031911411151783 1.2322197078521608 1.2018860278978734 1.557211140555455 1.0 15.218881678733805 -5.485442809998706 23.67544224528456 1.2728748727195902 1.8736379954514495 0.41931807758214334 0.2834639315007072 246.03180736438048 155595.75242118514 0.06733716463844105 0.14009023792063238 3.270071058790021e-06 5.485442809998706 0.6007631227318593 S(ph)STPEEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTPEEVK 8 0 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 1 S(0.635)S(0.183)T(0.183)PEEVK 104.42 0.0038583 45090000.0 533550.0 572490.0 479270.0 502490.0 591170.0 422800.0 520130.0 511520.0 435610.0 414280.0 True False 623869.4769071492 629323.0237453976 490697.61444159615 474337.1143945611 475334.4822493534 400627.62370313855 470859.5209849007 498093.1420002404 441979.9721568453 489385.68456132547 1.27480123875379 1.2859448970386391 1.0026807688121213 0.9692500809862193 0.9712880806381428 0.8186337204821434 0.9621440427031878 1.0177926280101963 0.9031322045168249 1.0 18.9006123749664 -5.3167067900953064 3.350601625191687 0.9474207929321111 1.2888767000761276 0.8580347379469404 0.05313227064194813 0.08130982721057081 1.8169043854498537 0.014814010150102915 0.037808772486393256 4.822732900896578e-06 5.3167067900953064 0.3414559071440165 S(ph)STPEEVK ddPTM_PC-9_Lapatinib_30min_R1 2 SSTPEEVK 8 0 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 1 S(0.986)S(0.014)TPEEVK;S(0.985)S(0.014)TPEEVK 121.83 0.0033551 15697500.0 85857.0 122557.0 99623.0 94387.0 155507.0 94482.0 109643.0 119051.0 134646.0 111306.0 True False 84632.66343575457 122273.2267963798 91432.381495901 101328.53484580191 146360.38399852527 90441.22510829926 115319.77805268088 124582.54407704268 119480.7495947624 130545.09379407782 0.6483021381811128 0.9366359412116545 0.7003892589033387 0.7761956570013869 1.121148100972638 0.6927968143403496 0.883371214506051 0.9543257464241399 0.9152450400260285 1.0 16.994188713076007 -1.5228787454585249 0.14342546010954058 1.022240534139966 0.01530751212503472 0.26230066562215415 0.12486736452842331 111.22578244903083 1.0607594203559183 0.49870965443503434 23.064772764576126 0.029999999987691258 1.5228787454585249 -1.0069330220149313 S(ph)STPLPTISSSAENTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSTPLPTISSSAENTR 16 0 P42166;G5E972;P42167;H0YJH7;P42167-2;P42167-3 P42166;G5E972 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 S(0.878)S(0.103)T(0.02)PLPTISSSAENTR;S(0.976)S(0.024)TPLPTISSSAENTR 164.7 3.0792e-05 7307200.0 14669.4 15594.9 19693.4 17396.4 29133.0 19597.7 17729.8 12075.5 14718.8 16427.8 True False 17152.639686143226 17143.058608896394 20162.9653436354 16421.736107889774 23424.597782990375 18569.96211222089 16050.304991363872 11758.530920049847 14934.034604766131 19406.03009760675 0.8838819480269989 0.8833882315276098 1.039005156759084 0.846218212859259 1.2070782980945298 0.9569171035404624 0.8270782282947854 0.6059215027961834 0.769556397143168 1.0 14.244217394856046 -7.348164097192707 3.9320169220914396 0.7594101070100849 0.974160146923687 0.2720369192967991 0.13192097748868456 0.2647140530686861 7.597031977042831 0.057483205789204225 0.03773699961732423 4.485758645267582e-08 7.348164097192707 0.2147500399136021 S(ph)STPLPTISSSAENTR ddPTM_PC-9_Lapatinib_30min_R1 1 SSTPLPTISSSAENTR 16 0 P42166;G5E972;P42167;H0YJH7;P42167-2;P42167-3 P42166;G5E972 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 S(0.333)S(0.333)T(0.333)PLPTISSSAENTR 214.65 5.9527e-22 641060000.0 62396.0 78865.0 46469.0 26070.0 34049.0 41755.0 49091.0 38576.0 42343.0 27178.0 True False 61506.221597974996 78682.39293795108 42648.49819552731 27987.274766970575 32046.304762909607 39969.235985659056 51632.69177589221 40368.381788611696 37573.88544844276 31875.681087591332 1.929565722186822 2.4684144856933212 1.3379635113782606 0.8780133886414603 1.0053527852424367 1.253910022371833 1.6198145424410069 1.2664319760786673 1.1787633759163703 1.0 14.960168547911305 -5.34560716079676 5.58002913218351 1.1938362169619599 2.1940258236968773 0.7591219757948602 0.22757568326645303 0.09970786706524316 5.03937932634707 0.06326762545618679 0.13567110110900704 4.5122467333542256e-06 5.34560716079676 1.0001896067349174 S(ph)STPLSEAK ddPTM_PC-9_AZD4547_30min_R2 1 SSTPLSEAK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.431)S(0.431)T(0.138)PLSEAK 133.75 0.0011541 34500000.0 281500.0 307600.0 301340.0 348100.0 352180.0 333530.0 259370.0 374540.0 278680.0 311100.0 True False 371011.1444362604 407025.6845541522 297344.03470794176 267850.92309138854 303285.88606930367 312674.3163745844 282453.42753373215 316663.4490729841 293410.4558635039 300208.48369147046 1.2358449697162959 1.355810067554452 0.9904584675679167 0.8922163684310256 1.0102508841189042 1.041523918744166 0.9408575802408519 1.0548117933883063 0.9773556438366579 1.0 18.195605221570872 -5.268603347392897 24.96196860261251 0.9879315790972537 1.2958275244630895 0.8499952930057 0.05165299364337721 161.24919535522844 561854.5595286769 0.013313207542368604 0.028666387239650527 5.387616230796224e-06 5.268603347392897 0.30789594536583575 S(ph)STPPGESYFGVSSLQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSTPPGESYFGVSSLQLK 18 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.359)S(0.359)T(0.281)PPGESYFGVSSLQLK;S(0.333)S(0.333)T(0.333)PPGESYFGVSSLQLK 100.41 0.00033393 49674000.0 56975.0 45194.0 62789.0 80558.0 80509.0 78042.0 75295.0 75808.0 72365.0 51476.0 True False 66619.74219245571 49680.56164325924 64286.127888608564 76044.59643255977 64733.83938869222 73949.34013491079 68162.51251140694 73818.12032521555 73423.20122387024 60808.19131620823 1.0955718423859524 0.8170044293032122 1.0571951984941428 1.2505650108407407 1.0645578825403679 1.216108200791031 1.1209429360751015 1.2139502709652141 1.2074557659849279 1.0 15.89197805807487 -5.52217546423402 20.82295319535357 1.15938708076957 0.9514909888219247 0.4060817673793875 0.09567608807829861 2.294528451427796 67920.79439776587 0.023671835893075727 0.04192892495181435 3.004862028996281e-06 5.52217546423402 -0.20789609194764536 S(ph)STPSHGQTTATEPTPAQK ddPTM_PC-9_AZD4547_30min_R2 1 SSTPSHGQTTATEPTPAQK 19 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 S(0.333)S(0.333)T(0.333)PSHGQTTATEPTPAQK 264.01 4.501699999999998e-158 0.0 4841.1 5670.3 14052.0 22982.0 17810.0 16111.0 10550.0 17537.0 13451.0 15819.0 True False 6380.469098864595 7503.113586239945 13865.66129858631 17683.854968360494 15337.388922977723 15103.57662312515 11488.929561941888 14827.05961016957 14161.992399239241 15265.18162492886 0.41797531504276025 0.49151813392033006 0.9083194448170169 1.1584437973198962 1.0047301958026458 0.989413489745854 0.752623181579435 0.971299259614192 0.9277316672152756 1.0 13.897957134362754 -5.261510819678046 3.95256123438366 0.9684536991090588 0.4368258305180641 0.8268027541265092 0.09382934962514902 0.08421942137504758 3.1044075335612416 0.026758104969650493 0.07022079716131127 5.476324574989142e-06 5.261510819678046 -0.5316278685909946 down S(ph)STPTSYQAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTPTSYQAPK 11 0 O94929 O94929 ABLIM3 Actin-binding LIM protein 3 1 S(0.333)S(0.333)T(0.333)PTSYQAPK 122.18 0.00069485 2820500.0 19531.0 19286.0 20867.0 22208.0 23641.0 20350.0 18492.0 21041.0 17349.0 15058.0 True False 22837.212545166356 21200.586623266317 21364.548418538187 20963.75775930744 19008.715758338483 19282.81017587241 16740.303889513758 20488.696044782322 17602.69630391661 17787.896200937583 1.2838624808234842 1.1918546400191414 1.2010722446992963 1.178540594261083 1.0686320374039822 1.0840410781605547 0.9411064524106787 1.1518335734218184 0.9895884316543735 1.0 14.118608270708068 -6.138540300516095 1.044821289897644 1.0302756881646133 1.2436063375231905 0.7104425132705325 0.05622379235745689 0.2980687902957718 0.6739574240706457 0.02323595299416319 0.04098213618159984 7.268749454567075e-07 6.138540300516095 0.21333064935857715 S(ph)STPTSYQAPK ddPTM_PC-9_Lapatinib_30min_R1 1 SSTPTSYQAPK 11 0 O94929 O94929 ABLIM3 Actin-binding LIM protein 3 1 S(0.33)S(0.33)T(0.33)PT(0.007)S(0.001)Y(0.001)QAPK 80.87100000000001 0.043798000000000004 0.0 18079.0 20051.0 16547.0 15595.0 16154.0 13643.0 13065.0 11795.0 14489.0 10350.0 True False 17821.190144717457 20004.573141429762 15186.569533267135 16741.908323394957 15203.853479985946 13059.52069338634 13741.441772464028 12343.038759764479 12857.096244066 12138.983709491884 1.4680957295282029 1.6479611160353982 1.2510577406403667 1.3791853357792951 1.2524815786759427 1.0758331179878473 1.132009244045622 1.0168098957174674 1.0591575499036712 1.0 13.567360022012043 -5.9538595253696975 0.5381630250850107 1.0065097438960864 1.6417419294476692 0.8334236487609996 0.08319029604563487 0.5229402470026248 0.264127202356807 0.0582325110410957 0.18246004523320722 1.1120913803962435e-06 5.9538595253696975 0.6352321855515828 S(ph)STQTLEDSWR ddPTM_PC-9_AZD4547_30min_R2 1 SSTQTLEDSWR 11 0 H0YBE8;H3BLZ3;Q8IX03;Q8IX03-2;H0YAU4 H0YBE8 WWC1 Protein KIBRA 1 S(0.597)S(0.381)T(0.022)QTLEDSWR 124.47 0.00050991 5231700.0 19876.0 21686.0 26305.0 29309.0 34227.0 30664.0 19302.0 34723.0 28007.0 25376.0 True False 26196.154553517306 28695.5754071565 25956.178512618328 22552.262869536058 29475.17185102519 28746.575232543575 21019.840607071328 29357.35820516154 29487.39284257627 24487.59396385328 1.069772497542473 1.1718413597315736 1.059972594732372 0.9209668741986653 1.2036777436988784 1.1739240398618613 0.8583873384252947 1.1988665872399158 1.2041768123933823 1.0 14.579763407965745 S(ph)STQTLEDSWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTQTLEDSWR 11 0 H0YBE8;H3BLZ3;Q8IX03;Q8IX03-2;H0YAU4 H0YBE8 WWC1 Protein KIBRA 1 S(0.549)S(0.309)T(0.124)QT(0.017)LEDSWR 75.911 0.021199000000000003 2798600.0 8846.0 15573.0 12734.0 12489.0 17607.0 13982.0 16066.0 14045.0 14647.0 12472.0 True False 10343.453083535998 17118.984521628463 13037.626853963933 11789.2818198843 14157.034742907059 13248.759306095739 14544.112172232737 13676.33363190759 14861.184665598397 14733.074871702329 0.7020566428670343 1.16194240989766 0.884922323920662 0.8001915365629382 0.9609015678117767 0.8992528322477 0.987174252414034 0.9282742232020817 1.0086953874199152 1.0 13.846770939536583 -7.700656800922994 0.9394238885082271 0.9997060474340795 0.908898175154886 0.10355569697633449 0.11234387461585878 1.6072184284729816 2.5832295857548644 0.0959621658076772 0.041226237876505104 1.9922470805353658e-08 7.700656800922994 -0.09080787227919351 S(ph)STQTLEDSWR ddPTM_PC-9_Lapatinib_30min_R1 1 SSTQTLEDSWR 11 0 H0YBE8;H3BLZ3;Q8IX03;Q8IX03-2;H0YAU4 H0YBE8 WWC1 Protein KIBRA 1 S(0.618)S(0.36)T(0.02)QT(0.001)LEDSWR 69.86399999999999 0.033655000000000004 2649800.0 7429.2 9206.5 12515.0 11045.0 16334.0 14975.0 12549.0 14597.0 19420.0 17367.0 True False 7323.258245651578 9185.182914895675 11486.06500929704 11857.286145039894 15373.266233879578 14334.554158429995 13198.725817271417 15275.229908968397 17232.715098334043 20368.862809927115 0.35953201285652836 0.45094235258038645 0.5639031062499528 0.5821280380592009 0.7547434718047761 0.7037483777171794 0.6479854049995757 0.7499304232892055 0.8460322630252771 1.0 14.314077816688028 -5.395274572219206 0.19428290450172314 1.029753644627992 4.476498885704508e-16 0.908176223374305 0.0540597018865186 3.8048980482080976 0.17637677233628038 0.15975963683432928 0.978588739503003 4.024625066544037e-06 5.395274572219206 -1.0297536446279916 down S(ph)STSGSDFDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSTSGSDFDTK 11 0 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 S(0.898)S(0.102)TSGSDFDTK;S(0.498)S(0.498)T(0.003)SGSDFDTK 118.61 0.001047 9303600.0 46707.0 57610.0 70998.0 63685.0 85292.0 74820.0 63131.0 66178.0 61616.0 56261.0 True False 54613.57259469997 63329.14006877384 72690.86158141433 60116.93591955579 68579.64487374503 70896.30748691768 57150.774651140644 64440.89762138699 62517.017433980334 66460.67393816901 0.8217426841850736 0.952881400626353 1.093742468652086 0.9045489965311659 1.0318830792710194 1.0667407247912548 0.8599186746783559 0.96960945176901 0.9406618038833369 1.0 16.02021330216598 -4.790575075703509 4.369298787658952 0.9821942124646486 0.8118147983723892 0.33841427896447496 0.06736666907623669 0.22164781297247343 8.626186672069501 0.0168073028598584 0.11239986251603094 1.6196639813115275e-05 4.790575075703509 -0.17037941409225932 S(ph)STSSEPTPTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTSSEPTPTVK 12 0 Q69YQ0-2;Q69YQ0;F8WAN1;A0A494C1J1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 S(0.5)S(0.5)T(0.001)SSEPTPTVK 92.792 0.005668600000000001 8328800.0 32684.0 46301.0 38736.0 28977.0 34966.0 22685.0 32309.0 28216.0 22383.0 20564.0 True False 38216.75566157477 50897.45728735112 39659.61314709808 27353.51263470153 28114.66330553122 21495.358665339856 29248.45762309645 27475.35989732322 22710.30903052425 24292.09041546558 1.5732180725477638 2.0952275583062714 1.632614257101923 1.1260254744189035 1.1573587461881005 0.8848706841488956 1.2040321406211874 1.1310413977312963 0.9348849210632657 1.0 14.568199023589125 -5.697853970932678 3.190637529386665 1.0632747040534332 1.843093265648708 0.8255919855821349 0.15027896354333514 0.08673282607287552 1.776127829524135 0.040555433160243716 0.07376574237992649 2.005146133092003e-06 5.697853970932678 0.7798185615952749 S(ph)STSSIDSNVSSK ddPTM_PC-9_Lapatinib_30min_R1 2 SSTSSIDSNVSSK 13 0 Q8IVL0-3;Q8IVL0-2;Q8IVL0;H0YHA8;A0A2R8YFX5 Q8IVL0-3 NAV3 Neuron navigator 3 1 S(0.982)S(0.018)TSSIDSNVSSK;S(0.979)S(0.02)TSSIDSNVSSK 180.95 8.9625e-05 11676200.0 37357.0 52505.0 57056.0 56714.0 60398.0 49623.0 50627.0 48259.0 60709.0 54578.0 True False 36824.282329565205 52383.42789839759 52365.07592252912 60884.9367523579 56845.50838703677 47500.73996686288 53248.21834018653 50501.289318141105 53871.3131258888 64011.734579386306 0.575273933311342 0.8183410157934795 0.8180543187372435 0.9511527402346737 0.8880482424130828 0.7420630026507599 0.8318508893732439 0.7889379916038712 0.8415849606305932 1.0 15.966048782594102 -14.522877463753515 0.02424549275569548 2.087570303796448 2.8936625571711696e-10 0.34150150176046035 0.0894353465453633 3270.655826365661 5.968534170694569 368.96431238651286 177.2425548688841 3.000008852486735e-15 14.522877463753515 -2.0875703035070816 S(ph)STVAPAQPDGAESEWTDVETR ddPTM_PC-9_AZD4547_30min_R2 1 SSTVAPAQPDGAESEWTDVETR 22 0 Q02241;H7BYN4;A0A2U3TZL8;Q02241-2;Q02241-3 Q02241;Q02241-2 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 S(0.79)S(0.181)T(0.03)VAPAQPDGAESEWTDVETR 110.44 9.475e-06 1125100.0 7534.9 5713.5 6866.5 10107.0 11049.0 9950.7 5536.2 9941.8 7331.5 6882.5 True False 9930.841464343806 7560.2771414179 6775.445723508598 7776.987301593398 9515.037069622731 9328.481155963718 6028.9110749595 8405.523249836568 7719.028122446107 6641.545769869962 1.4952605625931337 1.1383309553802752 1.0201609622636476 1.1709604316625326 1.4326539934104874 1.4045647623604895 0.9077572125317963 1.2655974288348755 1.1622336711830326 1.0 12.69730334174469 -9.068447121017584 0.4614498271000838 0.984276735945811 1.2432167886598455 0.1548361096485762 0.17230384364884913 4.955893547255242 1.8885285602855395 0.3565520737169502 0.1067992978341838 8.541868454736708e-10 9.068447121017584 0.25894005271403453 S(ph)STVPSSNTASGGMTR ddPTM_PC-9_AZD4547_30min_R2 1 SSTVPSSNTASGGMTR 16 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;A2SY06;H0YKP9 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 S(0.89)S(0.076)T(0.034)VPSSNTASGGMTR 81.992 0.039629000000000004 0.0 6369.5 5053.1 6003.3 9670.7 10028.0 5624.8 6625.7 12536.0 5786.3 6306.1 True False 8394.86850616967 6686.415756243773 5923.692319513463 7441.269525825594 8635.785295879874 5273.080366814871 7215.374464318334 10598.8492486221 6092.152005034428 6085.325358427459 1.3795266500490013 1.098777035312315 0.9734388829859109 1.2228219671969245 1.4191164460779946 0.866523982898018 1.185700688020878 1.74170625633746 1.0011218211360737 1.0 12.57111868489629 -7.546291920425841 24.999949594530616 1.3155889742537874 1.1519578835136723 0.001750530057257338 0.24988289984733472 630.4087415637388 673124.9818048467 0.11321737041172635 0.0653699450406486 2.8425497838554863e-08 7.546291920425841 -0.16363109074011506 S(ph)SVDLEESSTK ddPTM_PC-9_AZD4547_30min_R2 2 SSVDLEESSTK 11 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 S(0.996)S(0.004)VDLEESSTK;S(0.928)S(0.072)VDLEESSTK 242.97 3.7214e-27 15765400.0 74989.0 85217.0 109986.0 113024.0 117964.0 115676.0 101276.0 114458.0 105829.0 100088.0 True False 98833.9421319032 112761.72874073846 108527.5137764242 86968.06300339289 101586.73480685808 108442.76143359345 110289.36780239106 96771.1460831833 111422.90488581455 96583.94958441639 1.023295718979894 1.1674996645501885 1.123659927383368 0.9004401184420501 1.0517972731905019 1.122782428138458 1.1419016128139992 1.0019381739882494 1.1536379011755842 1.0 16.559495840050545 -6.689629493373117 24.998658556402013 1.087790577440195 1.0550930183866503 0.03336998448470263 0.08114324611188597 196.08061727160168 68256.01379074532 0.027723283313868155 0.02772328044829629 2.0434805415625178e-07 6.689629493373117 -0.03269755905354477 S(ph)SVDLEESSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSVDLEESSTK 11 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 S(0.691)S(0.309)VDLEESSTK;S(0.922)S(0.078)VDLEESSTK 171.26 0.00069335 10879300.0 72001.0 92092.0 86230.0 93984.0 103085.0 89199.0 111070.0 85950.0 85071.0 87735.0 True False 84189.34721542802 101234.28514517487 88286.05022909596 88718.38118023901 82886.23425186424 84521.24741413485 100548.6455228366 83693.90357155273 86315.0024364798 103640.66099012239 0.8123196669254338 0.9767815467215434 0.8518476183542497 0.8560190598233877 0.7997462912723398 0.8155220799121521 0.9701660001224762 0.8075392685842605 0.8328295247432489 1.0 16.661230596187977 -10.675267366903562 4.375524388413482 1.0000189696567459 0.8601745598327787 0.3269297855086385 0.061021019119920666 87088904.33205429 1.2801008032577204 23989.70941696116 0.014741773130392023 2.1121883023442035e-11 10.675267366903562 -0.13984440982396718 S(ph)SVDLEESSTK ddPTM_PC-9_Lapatinib_30min_R1 2 SSVDLEESSTK 11 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 S(0.5)S(0.5)VDLEESSTK;S(0.852)S(0.148)VDLEESSTK 152.4 0.00033797 15938800.0 65521.0 61181.0 75733.0 62985.0 81759.0 77766.0 85107.0 79682.0 81520.0 73355.0 True False 64586.65852492019 61039.33915344942 69506.52507783414 67617.12701180067 76950.09636437864 74440.12946140004 89513.42402825084 83384.31661344244 72338.35915634347 86034.31401060648 0.7507081246321998 0.709476676316898 0.8078930584518317 0.7859320759326877 0.8944116920010785 0.8652376707766033 1.0404386326276216 0.9691983666326747 0.8408082285333902 1.0 16.39262456005465 -6.292859970913224 1.0130432225636072 0.9571742124383847 0.7350394671755852 0.7072510021861149 0.05624309628410863 0.29684801369834407 0.6436807894518427 0.02618004916979298 0.039188004586013 5.094951205214342e-07 6.292859970913224 -0.22213474526279953 S(ph)SVGNGNLHR ddPTM_PC-9_AZD4547_30min_R2 4 SSVGNGNLHR 10 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 S(0.5)S(0.5)VGNGNLHR;S(0.5)S(0.5)VGNGNLHR;S(0.5)S(0.5)VGNGNLHR;S(0.866)S(0.134)VGNGNLHR 184.98 6.9743e-05 82851700.0 101417.0 117568.0 153177.0 269033.0 312599.0 212538.0 159386.0 338349.0 221297.0 232577.0 True False 133665.49639535462 155569.55683245306 151145.77289592626 207011.59836841564 269200.0247015114 199247.96526136054 173571.04522840487 286064.93653653725 232994.30763322028 224434.5500209296 0.5955655953278569 0.6931622462670985 0.6734514489049533 0.9223695654216822 1.1994589276758287 0.8877775959306609 0.7733704334391409 1.2746029366238858 1.0381392152477968 1.0 17.775935259594824 -5.832625764323139 3.5516596691612152 1.0255727790763827 0.6525040081257814 0.6067415409215096 0.13482303409720695 0.16476837353902657 4.130896315915163 0.040654475968287064 0.06551242907847682 1.4701926108859348e-06 5.832625764323139 -0.3730687709506013 S(ph)SVGNGNLHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSVGNGNLHR 10 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 S(0.5)S(0.5)VGNGNLHR;S(0.893)S(0.107)VGNGNLHR;S(0.5)S(0.5)VGNGNLHR;S(0.858)S(0.142)VGNGNLHR 165.58 7.7366e-05 61243700.0 186853.0 194244.0 269033.0 200990.0 378904.0 235681.0 179211.0 276129.0 176025.0 141533.0 True False 218483.52238502743 213527.2606061262 275447.7670333339 189729.1819183718 304660.48118512315 223321.47346731136 162234.83670471836 268880.9063328598 178599.03261841755 167191.81252538884 1.306783622265293 1.2771394566567134 1.6474955494097887 1.1347994800257373 1.8222212953092967 1.3357201533621688 0.9703515635975432 1.6082181434095586 1.068228341572028 1.0 17.351144674019274 -8.535086437978391 0.6997384702405564 0.9929052800104441 1.4094597006946818 0.21454439549700433 0.2454579930868674 1.273395734775229 1.419931632908715 0.23818870884754617 0.09405829243476256 2.9168464139476986e-09 8.535086437978391 0.41655442068423776 S(ph)SVGNGNLHR ddPTM_PC-9_Lapatinib_30min_R1 4 SSVGNGNLHR 10 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 S(0.874)S(0.126)VGNGNLHR;S(0.5)S(0.5)VGNGNLHR;S(0.877)S(0.123)VGNGNLHR;S(0.5)S(0.5)VGNGNLHR 190.78 0.00013555 61683600.0 329359.0 294204.0 255772.0 237991.0 210612.0 169379.0 132171.0 150520.0 288585.0 205610.0 True False 324662.280262956 293522.78871384007 234743.4134684722 255493.65205470272 198224.21623912363 162135.05501173396 139014.1676623302 157513.70870027537 256081.51836522782 241149.41454189603 1.3463117083643215 1.2171822571970001 0.9734355520389999 1.0594827797531916 0.8219975014896219 0.6723427271002786 0.5764648772895056 0.6531788974047448 1.0619205476890659 1.0 17.879567781992442 -5.475309036669712 0.924220594395798 0.7623359320051679 1.389300280663499 0.587682532630819 0.15407333075560598 0.6315782674207846 0.8297470788568948 0.061867411751455145 0.32275856696139593 3.3472716815395204e-06 5.475309036669712 0.6269643486583312 S(ph)SVSDAPVHITASGEPVPISEESEELDQK ddPTM_PC-9_AZD4547_30min_R2 1 SSVSDAPVHITASGEPVPISEESEELDQK 29 0 O14646;O14646-2;A0A087WVF4;H0Y8V4 O14646 CHD1 Chromodomain-helicase-DNA-binding protein 1 1 S(0.444)S(0.444)VS(0.111)DAPVHITASGEPVPISEESEELDQK 78.485 1.9764e-06 3204900.0 2918.6 2804.8 5955.3 10407.0 7337.0 8744.0 6379.2 8624.1 7549.6 6179.7 True False 3846.6540893487418 3711.39674914657 5876.328830876102 8007.8269365471915 6318.384195838712 8197.23629772245 6946.936441852107 7291.443507102897 7948.656443186132 5963.350583954289 0.6450491271968839 0.6223676936138725 0.9854072384554519 1.3428402076668138 1.0595359281474612 1.3746024457758568 1.1649384593527627 1.2227091807619253 1.332917850675046 1.0 12.54190743961375 -5.4318816387421 3.0479281276389667 1.2209302833652211 0.6295935414929275 0.7973882796481448 0.11577497604438003 0.09717299805923955 1.7181776524606305 0.029497487537471296 0.06939506385182702 3.6992898533008282e-06 5.4318816387421 -0.5913367418722937 S(ph)SVSDAPVHITASGEPVPISEESEELDQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSVSDAPVHITASGEPVPISEESEELDQK 29 0 O14646;O14646-2;A0A087WVF4;H0Y8V4 O14646 CHD1 Chromodomain-helicase-DNA-binding protein 1 1 S(0.669)S(0.17)VS(0.159)DAPVHIT(0.001)AS(0.001)GEPVPISEESEELDQK 104.24 1.8598e-11 2422900.0 2403.2 1456.3 5108.6 7477.2 6860.7 11353.0 14893.0 11222.0 10670.0 9268.7 True False 2810.0142946364103 1600.871839648592 5230.408398473385 7058.276725409472 5516.395084947035 10757.628694185727 13482.22722401732 10927.434390691844 10826.028564343194 10949.041939011177 0.2566447649291027 0.14621113413994 0.47770466380602344 0.6446478846940024 0.5038244547490726 0.9825178087825704 1.2313613646852941 0.9980265352494134 0.9887649188528826 1.0 13.418517016471082 -6.228172334825588 0.8214920301266703 1.0794849880641861 0.18937910184384685 0.8592586707688384 0.13067571158963612 0.24478381831361648 0.3530737636262575 0.07401490939348211 0.1306252897725829 5.913269398586956e-07 6.228172334825588 -0.8901058862203393 down S(ph)SVTDENWLSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSVTDENWLSPR 12 0 H3BRS1;Q12968;I3L3K7;H3BR83;Q12968-5;Q12968-6;Q12968-4;Q12968-3;Q12968-2 H3BRS1 NFATC3 Nuclear factor of activated T-cells, cytoplasmic 3 1 S(0.981)S(0.014)VT(0.006)DENWLSPR;S(0.9)S(0.1)VTDENWLSPR 141.65 7.3343e-05 5922500.0 20892.0 24632.0 20806.3 24933.0 24591.0 16209.0 21588.9 14316.0 16622.8 14660.7 True False 24428.602964191035 27077.302172783166 21302.40110033216 23536.084843876644 19772.570077970548 15358.971505686302 19543.843101899372 13940.220169055816 16865.87700275203 17318.568855962654 1.4105439755075633 1.5634838188988494 1.2300324165063965 1.359008647863726 1.1416976912132666 0.8868499258469803 1.128490654420938 0.8049291073064794 0.9738608971113242 1.0 14.080032095427425 -6.22795702107421 0.9857278373508042 0.937114887692841 1.470291463610836 0.7785032988709526 0.1084830228080787 0.23977454012092672 0.4905825332086757 0.048031898322557866 0.0782633638034743 5.916201795697244e-07 6.22795702107421 0.5331765759179949 S(ph)SVTVEER ddPTM_PC-9_AZD4547_30min_R2 2 SSVTVEER 8 0 V9GZ26;Q9BQ89 V9GZ26 FAM110A Protein FAM110A 1 S(0.969)S(0.016)VT(0.014)VEER;S(0.98)S(0.02)VTVEER 115.78 0.0036189 16657700.0 40235.9 34219.0 50057.0 51494.0 59223.0 37773.5 26229.6 50550.0 41999.0 53482.0 True False 53030.07924128933 45279.622560983524 49393.21147333725 39622.85387436928 51000.90871339187 35411.517073652656 28563.983586531867 42738.65902344029 44218.98139734215 51609.61145865387 1.027523318670466 0.8773486426507686 0.9570545113076031 0.7677417588410335 0.988205632089487 0.686141904052542 0.55346248071283 0.8281143340456965 0.8567974093888966 1.0 15.655352148927792 -6.761538975116015 24.999999998312912 0.7596953239583389 0.9142092510010156 0.2145484259673952 0.12757787558859243 3.888313169202605 975795.5477713372 0.04367401537771366 0.04100578386137299 1.7316536190834618e-07 6.761538975116015 0.15451392704267664 S(ph)SVTVEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSVTVEER 8 0 V9GZ26;Q9BQ89 V9GZ26 FAM110A Protein FAM110A 1 S(0.95)S(0.046)VT(0.004)VEER;S(0.943)S(0.05)VT(0.007)VEER 107.55 0.0038082 18344700.0 28004.0 23759.4 39559.0 32909.0 45348.0 34350.0 39868.0 31178.0 39178.0 28340.0 True False 32744.524095788158 26118.07621159567 40502.236588342945 31065.215422417543 36462.384933341826 32548.625530280973 36091.41442067563 30359.610535821612 39750.9041325059 33477.817660683446 0.9780961360048127 0.7801606567165488 1.209823083417681 0.9279343037614044 1.0891505922790026 0.9722445429442158 1.0780695081884506 0.9068575151323596 1.187380388273923 1.0 15.030917864644179 -5.244575161539925 24.999484739914415 1.0388798759431137 0.8791284134127422 0.2860918879186012 0.10517459196461784 998.4225752048725 1480054.1154590456 0.024239758025951526 0.06376297027657007 5.694096702363413e-06 5.244575161539925 -0.15975146253037154 S(ph)SVTVEER ddPTM_PC-9_Lapatinib_30min_R1 2 SSVTVEER 8 0 V9GZ26;Q9BQ89 V9GZ26 FAM110A Protein FAM110A 1 S(0.876)S(0.055)VT(0.069)VEER;S(0.935)S(0.059)VT(0.006)VEER 68.626 0.043082999999999996 15279400.0 48279.0 44558.0 53571.0 43138.0 46145.0 41703.0 50057.0 37375.0 48587.0 45208.0 True False 47590.53260671571 44454.82868863538 49166.59917004012 46310.51242414946 43430.84182456057 39919.459904441144 52648.70652921795 39111.578944145615 43114.62041620779 53022.14256412651 0.8975595912435704 0.8384200739317622 0.9272842777067453 0.8734183528728624 0.8191076354946248 0.7528828141216927 0.9929569795400682 0.7376461427759722 0.8131436854718522 1.0 15.69430734858876 -6.057359006647014 7.833129272925927 0.8418471954886034 0.8856839281220208 0.02478970234180844 0.08489213811274554 1.004696108985248 125.41826368944184 0.024168879078133733 0.03146134006780844 8.762761538056313e-07 6.057359006647014 0.043836732633417363 S(ph)SWECTGSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSWECTGSGR 10 0 Q8NEV8-2;Q8NEV8;E9PPH6 Q8NEV8-2 EXPH5 Exophilin-5 1 S(0.88)S(0.119)WECT(0.001)GSGR 87.713 0.010451 4336500.0 24525.0 41691.0 32804.0 26317.0 27626.0 16065.0 22721.0 26854.0 26090.0 15068.0 True False 28676.598109170292 45829.806953779735 33586.1717698628 24842.543810865187 22212.883614900336 15222.52311918381 20568.702394205167 26149.110954164924 26471.516892569278 17799.70912177762 1.611071164870048 2.5747503310437696 1.8868944172110502 1.3956713360259796 1.2479352029254949 0.8552119034664072 1.1555639619436102 1.4690751840529777 1.4871881732146879 1.0 14.11956604478619 -5.754859313475901 2.878362951633575 1.2143705985763804 2.120413845083152 0.6325876164138267 0.28216811812956716 0.15725719406331473 2.6647623557118596 0.0822624337246449 0.14610565462094194 1.7584931727158136e-06 5.754859313475901 0.9060432465067716 S(ph)SYPER ddPTM_PC-9_AZD4547_30min_R2 2 SSYPER 6 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 S(0.932)S(0.068)YPER;S(0.97)S(0.03)YPER 95.352 0.034483 435340000.0 152908.0 150480.0 233320.0 282716.0 251739.0 194283.0 172448.0 247306.0 168586.0 202126.0 True False 201529.56331602042 199119.71720321476 230226.02435141994 217540.19411865837 216789.3851814422 182134.45329716476 187795.53792395766 209090.5402265266 177497.11178485962 195049.6302623665 1.0332219704540715 1.020866929793066 1.1803458639820887 1.1153068776702586 1.111457555135239 0.9337851758661158 0.9628089921080539 1.0719863449383282 0.9100099884634669 1.0 17.573481738017662 -6.75260936642833 24.99537518067791 0.9794104256031353 1.0944509751490858 0.5030987829797715 0.05782185068561861 172.19900746817657 487448.3446251277 0.019928501506832997 0.019642749261762724 1.767627028108114e-07 6.75260936642833 0.11504054954595055 S(ph)SYPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSYPER 6 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 S(0.819)S(0.181)YPER 87.75399999999999 0.039466 178950000.0 27109.0 27966.0 35577.0 35973.0 39747.0 32723.0 31377.0 24441.0 31183.0 23509.0 True False 31698.01827284392 30742.279659144777 36425.290606523864 33957.54943603957 31958.8606762269 31006.94827445078 28404.743410192128 23799.449647380097 31638.992382559903 27770.99560285839 1.1414073418952735 1.1069923490960676 1.3116307073547882 1.2227703292187484 1.1507999617031182 1.1165227461726046 1.0228204928766942 0.8569894283851489 1.139281890898553 1.0 14.761291278908558 -7.062273601475625 2.0443034185421864 0.9904666287757213 1.1930831423053263 0.5249980877741016 0.08170830773018596 0.25611450921010337 2.125572372434608 0.037441203393800415 0.027846991508898425 8.664158698646416e-08 7.062273601475625 0.20261651352960497 S(ph)SYPER ddPTM_PC-9_Lapatinib_30min_R1 1 SSYPER 6 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 S(0.991)S(0.009)YPER 113.41 0.008019199999999999 0.0 53748.0 35582.0 49302.0 41050.0 42211.0 47852.0 33896.0 43651.0 43616.0 39606.0 True False 52981.543663823955 35499.61206515157 45248.57987122355 44068.95393878564 39728.23197001899 45805.481508460245 35650.96902559823 45679.184815810026 38703.50678315849 46451.84432832231 1.1405692159249832 0.764223952320166 0.9740965192125834 0.9487019207957738 0.8552562884095467 0.9860853141741034 0.7674823150963966 0.9833664405862743 0.8331963422076751 1.0 15.50344825819185 -4.738520735244204 24.82686298993555 0.9016317637118207 1.1405702864857261 0.4081431071098842 0.08641012901494692 1720.6189690893978 1863773.8557155414 0.019640182730931474 1.0866892827953463 1.8259095695545424e-05 4.738520735244204 0.23893852277390537 S(ph)T(ph)EMEVHELSRHLT(ph)RFHRP ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STEMEVHELSRHLTRFHRP 19 3 Q4VY12;Q9C0D0 Q4VY12 PHACTR1 Phosphatase and actin regulator;Phosphatase and actin regulator 1 3 S(0.967)T(0.967)EMEVHELS(0.07)RHLT(0.996)RFHRP 41.088 0.040644 2112400.0 10747.0 12654.0 11339.0 14643.0 15814.0 11042.0 12871.0 9203.1 11304.0 10929.0 True False 12566.254837074535 13910.205492627409 11609.364763396965 13822.600183246523 12715.360221748862 10462.938081669936 11651.765702029597 8961.52837649048 11469.299614933043 12910.341186083602 0.9733480049791429 1.0774467763579778 0.899229896101507 1.0706611067836278 0.9848973035240219 0.8104307958141503 0.9025141577659732 0.6941356736683573 0.8883808297255616 1.0 13.656239507302736 -6.705217550447681 6.220376944873756 0.8427915557696153 1.0049971891854026 0.3945105155545474 0.08688706015591022 0.17972979440956835 14.338385851927022 0.027471981747559836 0.027182611413970537 1.9714349409424004e-07 6.705217550447681 0.1622056334157873 S(ph)T(ph)SS(ph)SRS(ph)RKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSSSRSRKK 10 3 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 4 S(1)T(0.823)S(0.203)S(0.562)S(0.559)RS(0.852)RKK 78.903 0.013069999999999998 0.0 4236.1 4020.6 5557.7 4098.3 5620.1 5160.9 5199.2 4018.2 4492.0 5265.1 True False 4953.188063211264 4419.738596780287 5690.216645694624 3868.68553786787 4518.881749225419 4890.253318754789 4706.69413705169 3912.726507634822 4557.687001970914 6219.620951491333 0.7963810177248174 0.7106122111381286 0.9148815804169275 0.6220130725072951 0.7265525961259565 0.7862622749674496 0.7567493539816321 0.6290940457869275 0.7327917629575285 1.0 12.602610944106868 -10.858230498222374 6.531169105648476 1.0000118425146485 0.7403582024916687 0.4859858791518481 0.0796810963279924 1.3552787374570571e-05 1.3792331690125344e-06 0.07609862334027694 0.018455785924456562 1.3860200149084803e-11 10.858230498222374 -0.25965364002297975 S(ph)T(ph)T(ph)PKS(ph)VAIWGR ddPTM_PC-9_Lapatinib_30min_R1 1 STTPKSVAIWGR 12 1 Q2T9J0 Q2T9J0 TYSND1 Peroxisomal leader peptide-processing protease;Peroxisomal leader peptide-processing protease, 15 kDa form;Peroxisomal leader peptide-processing protease, 45 kDa form 4 S(1)T(1)T(1)PKS(1)VAIWGR 74.53699999999999 0.019018 0.0 9773.0 9941.5 9537.9 10689.0 9169.2 6774.5 9634.3 9158.2 11704.0 9207.9 True False 9633.635227851291 9918.481067553937 8753.730679358707 11475.104717458706 8629.885683340797 6484.770427130816 10133.116913008056 9583.723405652827 10385.772271416148 10799.473246244474 0.8920467700775495 0.9184226713097418 0.8105701527991492 1.0625615209009553 0.7991024642189699 0.6004709932853346 0.9382973300602283 0.8874250796431739 0.9616924857911759 1.0 13.398673324941521 -8.223813740431554 1.7587989177582 0.9963784168261527 0.8567255831738464 0.16073338807880067 0.11163100426840031 0.7102558232679586 4.027734969908841 0.10915025372863232 0.03281582375484899 5.97291397101638e-09 8.223813740431554 -0.1396528336523063 S(ph)T(ph)VS(ph)GY(ph)FLAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STVSGYFLAGR 11 0 P53794 P53794 SLC5A3 Sodium/myo-inositol cotransporter 4 S(1)T(1)VS(1)GY(1)FLAGR 60.691 0.017122 7974100.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 S(ph)TAALEEDAQILK ddPTM_PC-9_AZD4547_30min_R2 4 STAALEEDAQILK 13 0 B1ALK7;A0A2R8YG42;Q14155-1;Q14155-5;Q14155-6;Q14155-2;Q14155-3;Q14155;E9PDQ5;Q15052-2;Q15052 B1ALK7 ARHGEF7;ARHGEF6 Rho guanine nucleotide exchange factor 7;Rho guanine nucleotide exchange factor 6 1 S(0.986)T(0.014)AALEEDAQILK;S(0.98)T(0.02)AALEEDAQILK;S(0.973)T(0.027)AALEEDAQILK;S(0.986)T(0.014)AALEEDAQILK 190.41 1.7014e-05 21104400.0 37866.6 43283.6 49737.0 75476.0 64193.6 66088.0 41011.1 50859.2 39521.2 48004.2 True False 49907.391125790826 57274.17724306919 49077.45488242151 58076.17429257572 55281.42670219326 61955.50691261216 44661.00845097206 43000.0792681494 41610.20994787108 46323.5875693413 1.0773645510742225 1.2363933850618989 1.0594484895833676 1.2537063155059416 1.1933753321554177 1.337450533594178 0.96410944821835 0.9282545140482269 0.8982510235327776 1.0 15.499459367938591 -7.376815557500494 6.9525952232707064 0.9377279173647998 1.1912357548658032 0.695119886160974 0.07961174081902206 0.14149102085761442 7.65775260949297 0.033020452558139825 0.022124948893158417 4.199372912041409e-08 7.376815557500494 0.2535078375010035 S(ph)TAALEEDAQILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STAALEEDAQILK 13 0 B1ALK7;A0A2R8YG42;Q14155-1;Q14155-5;Q14155-6;Q14155-2;Q14155-3;Q14155;E9PDQ5;Q15052-2;Q15052 B1ALK7 ARHGEF7;ARHGEF6 Rho guanine nucleotide exchange factor 7;Rho guanine nucleotide exchange factor 6 1 S(0.961)T(0.039)AALEEDAQILK;S(0.814)T(0.186)AALEEDAQILK;S(0.984)T(0.016)AALEEDAQILK;S(0.981)T(0.019)AALEEDAQILK 206.49 7.291399999999999e-10 15842000.0 45345.3 47719.4 54109.6 56502.4 72871.3 60932.0 76900.0 52205.1 64383.9 50405.4 True False 53021.36367950085 52456.666665472134 55399.77807580073 53336.75371125238 58592.69187600408 57736.61865534437 69615.47529221336 50834.771440875666 65325.392735128065 59543.50001107314 0.8904643440449522 0.8809805714430108 0.9304084923710931 0.8957611443958364 0.9840317056455827 0.9696544315434472 1.1691532288036002 0.8537417422795446 1.0971036758500874 1.0 15.861656406301922 -6.436937183692997 1.8563777562169386 1.0194649455292413 0.8972994153278087 0.34603843103014176 0.0774295777321389 0.4036090762760786 2.7710015270863813 0.027236121787842807 0.0315073581382091 3.656476750287703e-07 6.436937183692997 -0.12216553020143261 S(ph)TAALEEDAQILK ddPTM_PC-9_Lapatinib_30min_R1 4 STAALEEDAQILK 13 0 B1ALK7;A0A2R8YG42;Q14155-1;Q14155-5;Q14155-6;Q14155-2;Q14155-3;Q14155;E9PDQ5;Q15052-2;Q15052 B1ALK7 ARHGEF7;ARHGEF6 Rho guanine nucleotide exchange factor 7;Rho guanine nucleotide exchange factor 6 1 S(0.965)T(0.035)AALEEDAQILK;S(0.988)T(0.012)AALEEDAQILK;S(0.949)T(0.051)AALEEDAQILK;S(0.991)T(0.009)AALEEDAQILK 221.59 3.5109000000000003e-15 16732100.0 59999.4 52598.9 58164.5 44823.6 61391.8 72765.8 60331.4 56877.7 70742.3 46334.0 True False 59143.79755345759 52477.1104787168 53382.439331462854 48120.07707114624 57780.855024922705 69653.7763593646 63455.06468819259 59520.44558425233 62774.55722455594 54342.77016382582 1.0883471228124408 0.9656686679850022 0.9823282687012848 0.8854917945124957 1.0632666470761827 1.2817487247959767 1.1676818185178297 1.0952780913600373 1.1551593162312304 1.0 15.72980048945512 -6.523441696605734 24.99953845051231 1.1504210761707445 0.9788914249390933 0.46626473969238214 0.08007826067430614 16.000590715477788 710507.9114220417 0.025864664950115943 0.026093902521565387 2.9961137892916866e-07 6.523441696605734 -0.1715296512316512 S(ph)TCGDSEVEEESPGKR ddPTM_PC-9_Lapatinib_30min_R1 1 STCGDSEVEEESPGKR 16 1 O95696-2;O95696 O95696-2 BRD1 Bromodomain-containing protein 1 1 S(0.959)T(0.041)CGDSEVEEESPGKR 88.28299999999999 0.0018503 4561800.0 9221.5 7705.7 11542.0 9519.4 13863.0 14796.0 9310.5 12299.0 14903.0 11518.0 True False 9089.99971898401 7687.857925086796 10593.061313408427 10219.488431787484 13047.605595706656 14163.209571160613 9792.552133373629 12870.456439706935 13224.46720445274 13508.870953229716 0.6728911505969167 0.5690969994238323 0.7841559335405321 0.7565020398203003 0.9658546329208378 1.0484376984720885 0.724897896151152 0.952741090226334 0.9789468898058441 1.0 13.721619481434104 -5.805070876059163 1.4900760290133148 0.9356463492265434 0.625889808669343 0.6452318222346223 0.09251727927439356 0.2651913990778001 1.1930238839346992 0.03114387254155452 0.06774476231847171 1.5664954000835996e-06 5.805070876059163 -0.3097565405572005 S(ph)TDNLAFLK ddPTM_PC-9_Lapatinib_30min_R1 1 STDNLAFLK 9 0 A0A0A0MRY4;Q96N96-6 A0A0A0MRY4 SPATA13 Spermatogenesis-associated protein 13 1 S(0.94)T(0.06)DNLAFLK 77.67399999999999 0.022713999999999998 1409400.0 8601.7 11805.0 14777.0 11123.0 14282.0 14265.0 11594.0 12871.0 14279.0 11416.0 True False 8479.038180641415 11777.666247797037 13562.092100869551 11941.022525240269 13441.960839492353 13654.919203339148 12194.280590122315 13469.033647895598 12670.748655464045 13389.240389136166 0.6332725333336447 0.8796366265373249 1.0129097474322468 0.89183719002678 1.003937523625236 1.0198427100030671 0.910752233563345 1.005959506024268 0.9463381257793314 1.0 13.708786494213756 -4.787713618865014 2.651031161818085 0.9716020548187168 0.5672783446946137 0.8533477763166812 0.04260206153454609 0.1559877689950259 1.464697480798841 0.01050893055075943 0.14147077550024809 1.6303707723432653e-05 4.787713618865014 -0.40432371012410306 S(ph)TDSPGADAELPESAAR ddPTM_PC-9_AZD4547_30min_R2 2 STDSPGADAELPESAAR 17 0 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 S(0.676)T(0.187)DS(0.137)PGADAELPESAAR;S(0.966)T(0.034)DSPGADAELPESAAR 207.92 1.0647999999999999e-66 49373000.0 25167.8 24597.0 19805.5 19509.1 25415.3 26767.7 24443.5 26887.4 24124.6 16014.3 True False 33170.63687723954 32547.499229448887 19542.86612931619 15011.57840759036 21886.824295011556 25093.91148748228 26618.92414666604 22732.570140986125 25399.777104652967 15453.644231373548 2.146460496993807 2.1061374742516645 1.2646121417523526 0.971394072675381 1.4162888680054864 1.6238183765443064 1.7225014209027187 1.4710167906437959 1.6436108353709258 1.0 13.915659469755228 -5.2527032848102735 23.820370647187854 1.4123123935364545 2.126299243094176 0.596604696336082 0.24185778137997185 245.68004121626336 669878.0360362167 0.06643662272870719 0.16964625390568217 5.5885187863094365e-06 5.2527032848102735 0.7139868495577213 S(ph)TDSPGADAELPESAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STDSPGADAELPESAAR 17 0 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 S(0.999)T(0.001)DSPGADAELPESAAR;S(0.926)T(0.072)DS(0.001)PGADAELPESAAR;S(0.786)T(0.196)DS(0.017)PGADAELPESAAR;S(0.421)T(0.227)DS(0.352)PGADAELPESAAR 288.41 4.546999999999999e-97 32819800.0 61174.7 63202.0 76661.0 66540.2 77141.5 48767.9 49184.2 38885.7 40383.6 26331.699999999997 True False 71530.36845459978 69476.27687253329 78488.88897846141 62812.16832023899 62026.17683989117 46210.425473018615 44525.116513228546 37864.991577804845 40974.133751734764 31105.428768377486 2.299610430939285 2.233573997319867 2.523318021523467 2.0193313774248733 1.9940627503244208 1.4856064456503242 1.431425904615526 1.2173113529397572 1.3172663221215597 1.0 14.924878772565132 -6.736999818862307 0.919208623802263 1.1698484540855165 2.361243825943555 0.9336189676779424 0.12807077126383168 0.12736553098433076 0.2334300573941672 0.0743714592593465 0.0704344737671347 1.832315186602144e-07 6.736999818862307 1.1913953718580383 up S(ph)TDSPGADAELPESAAR ddPTM_PC-9_Lapatinib_30min_R1 4 STDSPGADAELPESAAR 17 0 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 S(0.926)T(0.074)DSPGADAELPESAAR;S(0.622)T(0.005)DS(0.373)PGADAELPESAAR;S(0.971)T(0.028)DSPGADAELPESAAR;S(0.986)T(0.012)DS(0.003)PGADAELPESAAR 285.79 7.607199999999998e-97 67537200.0 60170.6 79308.29999999999 83204.8 72228.8 79541.0 59286.0 48814.0 44948.0 56228.0 35148.6 True False 59312.556210063354 79124.6665040374 76364.02252381625 77540.74690021327 74862.55476362276 56750.47598241603 51341.350071263645 47036.44817074135 49895.01053291072 41223.988677434434 1.4387874175438633 1.919384053861566 1.8524171234700804 1.8809617746343463 1.8159949380298979 1.3766371911867088 1.245424126059091 1.1409970184784326 1.2103392256223549 1.0 15.331196480902994 -6.9393537436030766 2.3600444174653 1.157877466475122 1.803262697721554 0.8208819712113213 0.13974120581828828 0.1200644935125814 1.3553613569587124 0.0569571439403403 0.04697793718860191 1.1498634151945255e-07 6.9393537436030766 0.6453852312464321 S(ph)TDSSSVSGSLQQETK ddPTM_PC-9_AZD4547_30min_R2 2 STDSSSVSGSLQQETK 16 0 Q9H8G2;A0A3B3ISJ3 Q9H8G2 CAAP1 Caspase activity and apoptosis inhibitor 1 1 S(0.814)T(0.181)DS(0.005)SSVSGSLQQETK;S(0.996)T(0.004)DSSSVSGSLQQETK 213.69 6.654e-22 26673000.0 22377.0 24869.5 31302.4 35595.0 43215.0 40142.0 31134.4 34079.0 31801.0 33355.0 True False 29492.420529485647 32908.07952542093 30887.30972337519 27389.122687267947 37215.343195198344 37631.91439423312 33905.30128467525 28812.873607513757 33481.93593697176 32187.251602471853 0.916276446766295 1.022394826742328 0.9596131445097713 0.8509307667997529 1.1562137598707045 1.1691558775817672 1.0533767127253406 0.8951641464566997 1.040223513038326 1.0 14.974201773116674 -6.258484859528198 24.999309838703244 1.0530049367117853 0.944975256853683 0.31709345041000514 0.08240503716050177 389.17372066644464 3292947.060238247 0.027378279862734677 0.033833065100252996 5.51461427218805e-07 6.258484859528198 -0.1080296798581023 S(ph)TDSSSVSGSLQQETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STDSSSVSGSLQQETK 16 0 Q9H8G2;A0A3B3ISJ3 Q9H8G2 CAAP1 Caspase activity and apoptosis inhibitor 1 1 S(0.997)T(0.003)DSSSVSGSLQQETK;S(0.999)T(0.001)DSSSVSGSLQQETK 298.1 6.968199999999999e-112 13032100.0 36988.0 40494.0 38198.0 44651.0 51078.0 50056.0 61322.0 56554.0 50679.0 44123.0 True False 43249.337853699915 44513.97670447719 39108.7851867217 42149.34923049517 41069.632566491004 47430.97524144813 55513.13622716649 55069.517423916135 51420.08449975152 52122.15062252419 0.8297688667322572 0.8540318496612611 0.7503294610760197 0.8086648138475055 0.7879496927117025 0.9099965115589685 1.0650584360802817 1.0565472983403388 0.9865303692501654 1.0 15.669608992013424 -7.016313146106024 3.3114175591092336 1.0306883230262682 0.8064658028401744 0.9028173168774725 0.03407035415579767 0.07160058688820262 1.6286835517767027 0.013961965212971088 0.011236562121949392 9.631343094804411e-08 7.016313146106024 -0.2242225201860938 S(ph)TDSSSVSGSLQQETK ddPTM_PC-9_Lapatinib_30min_R1 4 STDSSSVSGSLQQETK 16 0 Q9H8G2;A0A3B3ISJ3 Q9H8G2 CAAP1 Caspase activity and apoptosis inhibitor 1 1 S(0.945)T(0.055)DSSSVSGSLQQETK;S(0.589)T(0.408)DS(0.003)SSVSGSLQQETK;S(0.958)T(0.04)DS(0.001)SSVSGSLQQETK;S(0.986)T(0.013)DSSSVSGSLQQETK 265.43 5.923699999999998e-69 34324800.0 52327.3 51458.8 48659.9 47725.6 67856.2 63804.1 69275.2 59412.0 73813.5 59801.0 True False 51581.10310634842 51339.65031021927 44659.27085464588 51235.49983193446 63865.03172642204 61075.34737762159 72861.93088984319 62172.49841416935 65499.846339386124 70137.52317017622 0.7354280672443486 0.7319855049008894 0.6367386362687503 0.7305005582763542 0.910568677645843 0.8707941857232843 1.0388437971078146 0.886437039747167 0.933877379451544 1.0 16.09789886384424 -6.285207626162446 2.786466828232144 0.9418706344365627 0.6998157381324658 0.8264961765756351 0.05225501686661269 0.11050309057984031 1.7136596604885652 0.01700916738315105 0.021001400180822246 5.185520718896051e-07 6.285207626162446 -0.24205489630409693 S(ph)TECLLLSLLHR ddPTM_PC-9_AZD4547_30min_R2 1 STECLLLSLLHR 12 0 Q5TB30;H0YES2 Q5TB30 DEPDC1 DEP domain-containing protein 1A 1 S(0.5)T(0.5)ECLLLSLLHR 138.55 3.9528000000000005e-05 1025700.0 2088.0 3174.4 7064.2 8063.1 7441.6 8964.6 6611.6 9989.0 9176.7 8383.4 True False 2751.940566902 4200.462721224643 6970.524092333719 6204.276868653182 6408.4622913661415 8404.042144849342 7200.019591633652 8445.42957438467 9661.761627395643 8089.899717708367 0.34016992335246704 0.5192230890118514 0.8616329417626286 0.7669164124584072 0.792155961752944 1.0388314364952305 0.8900010930757506 1.0439473750086257 1.194299307103468 1.0 12.981906103799227 -4.952538864758578 0.4906361395435654 1.059335465258854 1.9788833974819565e-16 0.843293748236814 0.09659019790534858 1.5869986658788118 0.3330203956530469 0.0673199327930905 0.9555353698577361 1.115478323382941e-05 4.952538864758578 -1.0593354652588538 down S(ph)TEDLSPQK ddPTM_PC-9_AZD4547_30min_R2 2 STEDLSPQK 9 0 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 S(0.989)T(0.011)EDLSPQK;S(0.983)T(0.017)EDLSPQK 122.69 0.00018939 6388400.0 55857.0 135730.0 109900.0 84814.0 97269.0 93902.0 143171.0 143957.0 131867.0 75165.0 True False 73618.36410222457 179602.06815518535 108442.65419261572 65261.44266323762 83764.8783351557 88030.29309569224 155912.9416410219 121711.75345276737 138837.22040818384 72533.49622844534 1.0149567845228697 2.476125893470321 1.4950699998118655 0.8997421337266817 1.1548440746787796 1.2136502122886714 2.1495302135991317 1.6780075383300754 1.9141117914806414 1.0 16.14635977029986 -7.234428263177193 24.79863441275579 1.7419132350198123 1.39949771710034 0.08153836910666579 0.49097939964036075 1703.2956394608693 1563780.7238234372 0.1931315502924998 0.14955950267058254 5.8287004540016325e-08 7.234428263177193 -0.34241551791947233 S(ph)TEDLSPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STEDLSPQK 9 0 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 S(0.974)T(0.026)EDLSPQK;S(0.929)T(0.071)EDLSPQK 99.34299999999999 0.004171500000000001 12724200.0 61024.0 107824.0 91131.0 73085.0 156924.0 80533.0 90494.0 60753.0 77072.0 80695.0 True False 71354.15792106038 118528.05413600877 93303.90865624207 68990.28439476705 126175.86868835987 76309.70770975601 81921.75320017616 59158.29812312437 78199.03219410112 95324.36471873161 0.7485406079715422 1.2434182434442969 0.9788044109346945 0.7237423988959476 1.3236476221022833 0.8005267901330252 0.8593999387449179 0.6205999725010445 0.8203467437190768 1.0 16.540557390812253 -6.922462724478157 24.999999999690647 0.7986194593447014 1.0062308748564488 0.17696401488075353 0.1950330930432723 53.271688874384736 17173.653474216855 0.06619764668826815 0.058380835370428145 1.1954661282010876e-07 6.922462724478157 0.20761141551174744 S(ph)TEDLSPQK ddPTM_PC-9_Lapatinib_30min_R1 2 STEDLSPQK 9 0 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 S(0.993)T(0.007)EDLSPQK;S(0.988)T(0.012)EDLSPQK 123.51 0.0014914000000000001 19725800.0 149159.0 258760.0 88985.0 60220.0 115813.0 68364.0 76347.0 82117.0 110560.0 48831.0 True False 147031.9653075893 258160.8571181665 81668.9967920333 64648.779688031034 109001.10703711858 65440.23108426764 80299.87409125993 85932.45560284691 98107.56855158653 57271.37328678242 2.5672854843437567 4.5076770872150025 1.426000322763023 1.128814903115851 1.9032389269121086 1.1426342224514197 1.4020944406058484 1.500443426990062 1.7130297899496787 1.0 15.80552657722019 -5.278855847836349 24.88577238968262 1.418785367940961 3.5374811846167917 0.7412177495406399 0.5046342690355473 290.6121421386652 415245.1174337699 0.12048848936205012 0.25175975605933604 5.261918924011453e-06 5.278855847836349 2.1186958166758307 S(ph)TEFPR ddPTM_PC-9_AZD4547_30min_R2 1 STEFPR 6 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(0.966)T(0.034)EFPR 95.741 0.034543 8391300.0 8816.3 13295.0 16869.0 24964.0 17807.0 24067.0 18740.0 24041.0 19382.0 18921.0 True False 11619.700009568052 17592.34875210484 16645.306037991202 19208.93548995524 15334.805421193954 22562.08668541698 20407.823695809595 20326.015857221126 20406.492950862765 18258.581549104187 0.6363966433163668 0.9635112511227887 0.9116428893025299 1.0520497136261762 0.8398683862682816 1.2356976704208402 1.1177113425227085 1.1132308280660703 1.117638459262678 1.0 14.156287070854065 -4.051434681154938 0.5505400900895051 1.101907368173156 2.221945300867073e-11 0.6004765607506765 0.1030407423517984 5.890147455863885 0.7476111764290087 0.0537191879630376 4.951197167504455 8.883115702860896e-05 4.051434681154938 -1.1019073681509364 S(ph)TEFPR ddPTM_PC-9_Lapatinib_30min_R1 1 STEFPR 6 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(0.985)T(0.015)EFPR 91.318 0.03642 8750100.0 24258.0 22346.0 27952.0 21746.0 21643.0 23927.0 19101.0 22018.0 21518.0 15368.0 True False 23912.076471627614 22294.259209934156 25653.89445784028 23345.27338252944 20370.001291775174 22903.69798656122 20089.956318089215 23041.036660660815 19094.416245414614 18024.33832342718 1.3266548842210664 1.2368975110147116 1.423291884423661 1.2952083434977675 1.1301386451062791 1.270709502650207 1.11460159910432 1.278329126274398 1.0593684995690853 1.0 14.13765867840352 -7.8749614855360255 0.26148790209821476 0.9590891192758025 1.375288011369768 0.5970993341451409 0.07968127244560202 1.343222433626991 0.37185882862804304 0.20011479320864678 0.2067448084267816 1.3336396978626016e-08 7.8749614855360255 0.41619889209396554 S(ph)TELLIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STELLIR 7 0 K7EMV3;A0A590UJJ6;B4DEB1;K7EK07;K7ES00;P84243;K7EP01;Q71DI3;Q16695;P68431;Q5TEC6;Q6NXT2 K7EMV3 H3F3B;H3F3A;HIST2H3A;HIST3H3;HIST1H3A;HIST2H3PS2;H3F3C Histone H3;Histone H3.3;Histone H3.2;Histone H3.1t;Histone H3.1;Histone H3.3C 1 S(0.961)T(0.039)ELLIR;S(0.549)T(0.451)ELLIR 99.44200000000001 0.01184 2433900.0 18264.5 28498.4 15158.3 25451.2 29360.5 28065.8 34040.0 21915.8 21149.0 19655.7 True False 21356.319109681575 31327.532812635738 15519.73136017288 24025.251777903708 23607.520791112776 26593.980040982802 30815.484771741725 21340.53347170953 21458.264115022892 23219.1228155644 0.919772864777039 1.3492125891868774 0.6684030005547664 1.0347183211330853 1.0167275042486974 1.1453481792669682 1.3271597302153586 0.9190930097240537 0.9241634270799776 1.0 14.503025849877845 -4.498172564395811 19.641085099377268 1.0451445126528116 0.5366785149363289 0.036553723135666405 0.1890620491439114 56742427.41987732 1121771647.2412996 0.04699279502816219 958728452.0439632 3.175612008899653e-05 4.498172564395811 -0.5084659977164827 S(ph)TELLLGVK ddPTM_PC-9_AZD4547_30min_R2 2 STELLLGVK 9 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 S(0.994)T(0.006)ELLLGVK;S(0.996)T(0.004)ELLLGVK 115.7 0.001963 3366500.0 30808.0 36374.0 38587.0 35629.0 42445.0 42697.0 39364.0 43004.0 43170.0 38617.0 True False 40604.30315379154 48131.18416766163 38075.31116770211 27415.284512562703 36552.24440403086 40027.14984033112 42867.31974182754 36358.71993361077 45451.87806669824 37265.030584100015 1.0896087435687307 1.2915911623643725 1.0217437251734824 0.7356839396841945 0.9808725185811794 1.0741209442991744 1.1503363628022318 0.9756793262669173 1.2196924933181548 1.0 15.185534823255809 -5.322926910167772 10.341217597229463 1.013851217160269 1.1904606236789936 0.21935414956685562 0.128530376120139 0.8935320770152736 147.815805939802 0.03533001317642225 0.07367262404114162 4.75415229481889e-06 5.322926910167772 0.1766094065187247 S(ph)TELLLGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STELLLGVK 9 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 S(0.996)T(0.004)ELLLGVK;S(0.992)T(0.008)ELLLGVK 98.04 0.0045899999999999995 2836800.0 33195.0 41409.0 40086.0 38494.0 42196.0 37259.0 42180.0 30280.0 36263.0 33493.0 True False 38814.257868864726 45519.811857452805 41041.802267001556 36337.30597923185 33927.99670652047 35305.072449279156 38184.40504324519 29485.182084311982 36793.27777214409 39565.0157695579 0.9810247036152879 1.1505066021603017 1.0373255632209284 0.9184201060571924 0.8575251657709521 0.8923305542176373 0.965105265359834 0.7452336745180439 0.9299447265847816 1.0 15.271937711793328 -5.756482716609048 3.4833393789207654 0.8887501753454666 1.0715832243632433 0.4735883429473994 0.07493642670000339 0.17238002845297842 4.4045866838759515 0.02046168840789176 0.03507811621545659 1.7519321535513055e-06 5.756482716609048 0.18283304901777664 S(ph)TELLLGVK ddPTM_PC-9_Lapatinib_30min_R1 2 STELLLGVK 9 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 S(0.997)T(0.003)ELLLGVK;S(0.995)T(0.005)ELLLGVK 115.23 0.0019913 2945700.0 35655.0 46554.0 33898.0 28905.0 41564.0 39705.0 42937.0 40804.0 41052.0 33828.0 True False 35146.55316167379 46446.20707326926 31111.037290064014 31030.770124253337 39119.28723796805 38006.909706875645 45160.06776764549 42699.90280232556 36428.291463275425 39675.124727023314 0.8858586684602142 1.1706631647117183 0.7841446625339485 0.7821215519233848 0.9859902774627781 0.9579531247443963 1.138246396913941 1.0762386532144164 0.9181645102293422 1.0 15.27594713802957 -6.84727023591158 2.6132129602923984 1.0384338973571836 0.917097346468869 0.16568708623472506 0.11581456647028938 0.5166121276670514 7.180215167024227 0.04693499730447003 0.04131881240095735 1.4214440308721373e-07 6.84727023591158 -0.12133655088831463 S(ph)TELVLSPDMPR ddPTM_PC-9_AZD4547_30min_R2 2 STELVLSPDMPR 12 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 S(0.925)T(0.072)ELVLS(0.002)PDMPR;S(0.996)T(0.004)ELVLSPDMPR 131.32 0.00089372 6568400.0 24888.7 25925.3 31386.0 42778.8 33587.2 35246.7 28483.8 40821.3 31571.9 29975.5 True False 32802.78888288018 34305.146228126636 30969.801132751898 32916.80858587153 28924.197037273305 33042.71827709673 31018.80301956783 34513.30606515456 33240.7261786887 28926.066868832102 1.1340217469463592 1.185959583917387 1.0706537211985057 1.1379635100456558 0.9999353582508373 1.1423163206713154 1.072347760247718 1.1931558556390782 1.1491616309061934 1.0 14.820082550221498 -5.258527182153197 24.99245953730219 1.1015114741272574 1.1599906655406789 0.14490377126872733 0.061185617382001206 494.72875106435447 4245702.3829283025 0.015435753075750775 0.03740507033810026 5.514076891240994e-06 5.258527182153197 0.058479191413421505 S(ph)TELVLSPDMPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STELVLSPDMPR 12 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 S(0.884)T(0.115)ELVLS(0.001)PDMPR 155.66 0.00029102 8131400.0 29514.0 36177.0 32265.0 35592.0 52618.0 31423.0 36040.0 29344.0 23861.0 21309.0 True False 34510.1372719287 39768.41347453624 33034.3199656939 33597.895630820894 42307.88062147349 29775.12256297 32626.030292995656 28573.751092537994 24209.92198442296 25172.15301804881 1.3709648613364307 1.5798574498582496 1.312335895225482 1.3347247494773569 1.6807414364253268 1.1828595885946183 1.2961160004709291 1.1351333782235546 0.9617739875911322 1.0 14.61954099754302 -7.6494464539236935 1.0807065499604471 0.97308052049997 1.4395355382851536 0.6591841691551841 0.1269502660565487 0.31560418571235693 0.6724490842870516 0.10466623717451556 0.04452339083132593 2.241576402556446e-08 7.6494464539236935 0.4664550177851836 S(ph)TELVLSPDMPR ddPTM_PC-9_Lapatinib_30min_R1 5 STELVLSPDMPR 12 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 S(0.942)T(0.058)ELVLSPDMPR;S(0.84)T(0.16)ELVLSPDMPR;S(0.955)T(0.045)ELVLSPDMPR;S(0.984)T(0.016)ELVLSPDMPR;S(0.985)T(0.015)ELVLSPDMPR 182.37 0.0006032 12394900.0 75717.29999999999 69700.6 78324.29999999999 61022.799999999996 68382.20000000001 68143.4 58780.799999999996 60606.5 63228.4 46385.3 True False 74637.55741714776 69539.21254309214 71884.77839454114 65510.62027809332 64360.09344057795 65229.06563202387 61824.18220733669 63422.499244906 56106.9517674307 54402.93730047287 1.371939845911574 1.2782253310886527 1.3213400224608152 1.2041743245639773 1.183026076057451 1.1989989671285064 1.1364125776127776 1.1657918191919894 1.0313221041273266 1.0 15.731396926510829 -1.5228918041823674 0.12033811521843793 0.9081101967042777 2.377794538386496 0.8998202255175202 0.03513070626281115 26.15495994867519 0.21707968543085812 0.2319499124481036 6.443816713763956 0.029999097936567905 1.5228918041823674 1.4696843416822183 S(ph)TENVNKLPELSSFGKPSSSVQGTGLIR ddPTM_PC-9_AZD4547_30min_R2 2 STENVNKLPELSSFGKPSSSVQGTGLIR 28 2 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 S(0.499)T(0.499)ENVNKLPELSSFGKPSSSVQGTGLIR;S(0.749)T(0.251)ENVNKLPELSSFGKPSSSVQGTGLIR 77.175 6.411e-05 41347000.0 21540.5 25236.4 37536.0 53593.0 51325.0 42847.0 43188.0 53898.0 51242.0 48613.0 True False 28389.930929766517 33393.5727753004 37038.24811441331 41237.961853596025 44199.40968398827 40167.77031661868 47031.648333757956 45569.30255282659 53950.54750738366 46911.07366664559 0.6051861258070531 0.7118484009255086 0.7895416842856873 0.8790666814969271 0.9421956529512273 0.8562534850951089 1.0025702815494946 0.9713975611951722 1.1500599600589236 1.0 15.517640900119416 -4.092430315844226 0.3290867050266923 1.0582265088415044 2.7176239596299573e-14 0.8602836179322922 0.05618669290725237 3.820371216097475 0.234936882487262 0.055037175068316714 1.7560707850688402 8.082946125680695e-05 4.092430315844226 -1.0582265088414773 S(ph)TENVNKLPELSSFGKPSSSVQGTGLIR ddPTM_PC-9_Lapatinib_30min_R1 1 STENVNKLPELSSFGKPSSSVQGTGLIR 28 2 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 S(0.777)T(0.223)ENVNKLPELSSFGKPSSSVQGTGLIR 96.84200000000001 3.8138e-09 5235800.0 31768.0 21385.0 27255.0 26634.0 23149.0 23474.0 19035.0 23175.0 34427.0 22309.0 True False 31314.982494462303 21335.48434639048 25014.19910734246 28592.753208419435 21787.421332685088 22470.07174056664 20020.53916102968 24251.795104496992 30549.46872761822 26165.080925126025 1.1968234527564898 0.8154182441645828 0.9560145897856411 1.0927829075033413 0.8326907680901869 0.8587808998132656 0.765162516344606 0.9268763652555063 1.1675663765397308 1.0 14.67535510057345 -3.8916622173991873 3.4965425680831355 0.9291725623377157 44.76637631152811 0.29297626481576844 0.12033731547085814 591.6347170596761 44.16236477104941 0.03150924729271765 204748.5420900772 0.00012833283329541918 3.8916622173991873 43.837203749190394 S(ph)TEPELIQVK ddPTM_PC-9_AZD4547_30min_R2 2 STEPELIQVK 10 0 M0QXM4;Q15758-3;Q15758-2;Q15758 M0QXM4 SLC1A5 Amino acid transporter;Neutral amino acid transporter B(0) 1 S(0.976)T(0.024)EPELIQVK;S(0.955)T(0.045)EPELIQVK 107.09 0.0048878 4077400.0 38881.0 60142.0 51986.0 55883.0 55360.0 54344.0 59111.0 63982.0 48373.0 43364.0 True False 51244.3492249601 79581.72535908908 51296.631672951014 43000.03773374331 47674.219583158156 50945.86108913866 64371.76448681963 54095.05206009404 50929.89802456322 41845.839558974345 1.2245984251968516 1.9017834556033377 1.2258478313156422 1.0275821488332746 1.139282186368127 1.2174653830840085 1.5383073960339344 1.2927223501838598 1.2170839099257764 1.0 15.352796572312963 -5.447214455147803 24.02022868267658 1.2207128968977619 1.5633500294032454 0.31982346561539643 0.20688397854709478 98.68457649702032 31326.999258157557 0.05351927184371946 0.11140920621085677 3.570964599377467e-06 5.447214455147803 0.34263713250548355 S(ph)TEPELIQVK ddPTM_PC-9_Lapatinib_30min_R1 3 STEPELIQVK 10 0 M0QXM4;Q15758-3;Q15758-2;Q15758 M0QXM4 SLC1A5 Amino acid transporter;Neutral amino acid transporter B(0) 1 S(0.993)T(0.007)EPELIQVK;S(0.98)T(0.02)EPELIQVK;S(0.986)T(0.014)EPELIQVK 127.52 0.00031017 9132000.0 124343.0 150324.0 62104.6 45313.9 68508.8 55752.8 40944.3 44276.8 78139.0 37957.1 True False 122569.84601828676 149975.93401387875 56998.59951868868 48646.435368739076 64479.24707748304 53368.382710124606 43064.195512001475 46334.06176840525 69338.1629798518 44517.93416034345 2.753268953963994 3.3688879963230014 1.2803514042990565 1.0927379332905633 1.448388122531551 1.1988063623505947 0.9673448762670357 1.040795415203242 1.5575332568243516 1.0 15.442099026007885 -5.268845488713225 24.999999972351464 1.1966408169644283 3.061078504776297 0.9148984347548662 0.22725613973173292 119.70594515591857 404079.31744787924 0.057113578562265184 0.12279465418794991 5.384613197258263e-06 5.268845488713225 1.8644376878118687 S(ph)TEPSVTPDLLNFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STEPSVTPDLLNFK 14 0 A0A494BZV2;Q6WCQ1-2;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 S(0.982)T(0.018)EPSVTPDLLNFK 153.32 0.00026174 2471100.0 23952.0 29086.0 35982.0 37624.0 44939.0 38436.0 39978.0 38516.0 34022.0 26094.0 True False 28006.600526436134 31973.46585732262 36839.947342494896 35516.04925865379 36133.52554731076 36420.34849728906 36190.99442434462 37504.9958110753 34519.50738669956 30824.63564000967 0.9085784777317597 1.0372698717587368 1.195146238636394 1.1521968880162454 1.1722287967748197 1.1815337875402583 1.1740931781645958 1.216721464256164 1.1198674913741407 1.0 14.911796221024023 -4.962923316750737 2.6938042699046196 1.1617250565001531 0.9003191620499029 0.6327249328978983 0.057888878670185474 0.1791084618421207 2.2678251723175786 0.013965010754382499 0.08817801485700273 1.0891223823762707e-05 4.962923316750737 -0.2614058944502502 S(ph)TFHAGQLR ddPTM_PC-9_AZD4547_30min_R2 1 STFHAGQLR 9 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 S(0.998)T(0.002)FHAGQLR 107.45 0.0025013 20484000.0 25423.0 24110.0 58505.0 84109.0 57155.0 50644.0 44666.0 58074.0 44382.0 54341.0 True False 33506.98516874978 31903.086003252938 57729.18547351206 64718.96952109611 49220.014817113486 47477.22267404571 48641.18747049259 49099.99770776002 46727.94191235122 52438.53813011313 0.6389763399889328 0.6083900722803027 1.100892350016919 1.234187142298135 0.9386229397735368 0.9053879907224501 0.9275847345286712 0.9363342201861281 0.8910992483506598 1.0 15.678339846538684 -5.252244850517614 24.93377718586116 0.9908729611960178 0.6236831463817815 0.6868481344112939 0.09941305355223823 391.13645299120145 1060680.3430200773 0.028629713783984708 0.07346673406769645 5.594421051767686e-06 5.252244850517614 -0.3671898148142363 S(ph)TFHAGQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STFHAGQLR 9 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 S(0.5)T(0.5)FHAGQLR 61.958 0.036085 1761400.0 9177.2 8863.9 20690.0 29387.0 23916.0 27652.0 17238.0 21091.0 20642.0 14616.0 True False 10730.718702037824 9743.849412525682 21183.328067261955 27740.54166393946 19229.831482442492 26201.880441436075 15605.091847687547 20537.3835977617 20943.85019917267 17265.76509980766 0.6215026464223913 0.5643450699230368 1.2268977334516113 1.6066789686747498 1.1137549579344568 1.5175626617165063 0.9038169902972552 1.1894858686563785 1.213027634634389 1.0 14.075626645466286 -5.2636503006526105 23.79334098054387 1.2373205286212796 0.592923777921998 0.6102125237973486 0.2005980665110032 57.17529917188068 615324.0038204275 0.05153759922051073 0.1164734172850558 5.4494126975334195e-06 5.2636503006526105 -0.6443967506992816 S(ph)TFHAGQLR ddPTM_PC-9_Lapatinib_30min_R1 1 STFHAGQLR 9 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 S(0.5)T(0.5)FHAGQLR 70.41199999999999 0.02139 4727100.0 40024.0 20222.0 62737.0 31106.0 31328.0 41465.0 26876.0 25859.0 47976.0 16028.0 True False 39453.250420497345 20175.177201435974 57579.00603182332 33393.6390065741 29485.348633217774 39691.638609636015 28267.507774722035 27060.503542920695 42572.43767032305 18798.418444032468 2.09875370834836 1.0732380099688947 3.0629707601865674 1.7764068347555517 1.568501558841396 2.111434997992401 1.5037173397794812 1.439509585526383 2.2646818825249424 1.0 14.198323669168792 -11.703111464060516 0.27307486434159817 1.1943143693715251e-13 1.9499845211827276 0.19501410198893798 0.5259458915041633 61.705984082828515 2.3297554114951153 39.72203481426488 0.6586636505019837 1.9810185212849646e-12 11.703111464060516 1.9499845211826081 S(ph)TFHGQPR ddPTM_PC-9_AZD4547_30min_R2 2 STFHGQPR 8 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;A2SY06 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 S(0.5)T(0.5)FHGQPR;S(0.924)T(0.076)FHGQPR 72.789 0.017978 2140400.0 7010.1 5553.1 24281.0 40211.0 25629.0 22491.0 17999.1 31454.0 19428.0 26856.0 True False 9239.165980861928 7348.030978210862 23959.01807507643 30940.975203757 22070.855738742048 21084.634214555757 19600.985031123055 26593.507041014633 20454.924416951915 25915.77961433019 0.3565073525996922 0.2835350156376446 0.9244953627336852 1.193904858901027 0.8516377306487789 0.8135828645068799 0.7563339912137795 1.0261511494838338 0.7892845486940828 1.0 14.661543173959315 -5.263191777789365 24.986103145409107 0.9181350895339345 0.3200211410498376 0.7873482062970806 0.12460191425794677 63.03110831052302 898727.47621764 0.03373075819968895 0.07659141340667183 5.455169159841403e-06 5.263191777789365 -0.5981139484840969 S(ph)TFSTNYR ddPTM_PC-9_AZD4547_30min_R2 3 STFSTNYR 8 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.729)T(0.04)FS(0.157)T(0.074)NYR;S(0.938)T(0.016)FS(0.045)TNYR;S(0.967)T(0.018)FS(0.014)T(0.001)NYR 118.23 0.003512 1860980000.0 46530.4 42103.4 68836.0 96058.0 57428.0 65498.0 59323.0 60598.0 49258.1 72473.0 True False 61326.09930755596 55712.50067313814 67923.18966335665 73913.31218130582 49455.11347943652 61402.39970588112 64602.632076121205 51233.97150351006 51861.7826035958 69935.74232906433 0.876892090728115 0.7966241412151965 0.9712228311492264 1.056874635483614 0.7071507620057628 0.8779830979267825 0.9237427090163771 0.7325863685330173 0.7415633390945326 1.0 16.093742347336317 -6.268989179731232 24.983318290268386 0.8241695593388301 0.9194777202106824 0.16045721402457047 0.1054010161154427 1138.969861996178 3769000.209054846 0.03339960058804092 0.038607695418088346 5.382831934540594e-07 6.268989179731232 0.09530816087185234 S(ph)TFSTNYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STFSTNYR 8 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.467)T(0.057)FS(0.199)T(0.277)NYR;S(0.77)T(0.039)FS(0.19)T(0.002)NYR;S(0.971)T(0.016)FS(0.01)T(0.004)NYR;S(0.753)T(0.014)FS(0.067)T(0.166)NYR 123.11 0.0032991999999999995 1758182700.0 70988.6 77604.5 80522.5 81091.0 81455.3 55223.8 95419.0 77539.3 41723.5 53359.8 True False 83005.56789123947 85308.56188972674 82442.46178328175 76547.73417056934 65494.71869676361 52327.76671205618 86380.22154626412 75503.9755346794 42333.627254393 63033.50934405559 1.316848272530258 1.3533842995173775 1.3079148319870046 1.214397468380653 1.0390460467506895 0.8301579153151019 1.370385727292689 1.1978386785123498 0.6716051144054745 1.0 15.943831365497909 -6.056116173346936 2.6343386812757283 1.036260378834437 1.3286820228954292 0.38185861436793944 0.17775874866839514 0.3341414833001929 4.5920903771745225 0.057075294989532 0.08261075141282329 8.787874106185778e-07 6.056116173346936 0.29242164406099236 S(ph)TFSTNYR ddPTM_PC-9_Lapatinib_30min_R1 3 STFSTNYR 8 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.987)T(0.013)FSTNYR;S(0.974)T(0.021)FS(0.004)T(0.002)NYR;S(0.628)T(0.013)FS(0.306)T(0.053)NYR 102.95 0.0041206 1479630000.0 87811.0 73429.0 78484.0 82144.0 80319.0 88032.0 60709.0 51435.1 83160.0 42840.8 True False 86558.79903743476 73258.97966196432 72031.34847700124 88185.14378435121 75594.7943332296 84267.07657261491 63852.214968581604 53824.96251906422 73793.64508637796 50245.77519822221 1.7227080027316877 1.4580127259048907 1.4335802003817 1.755075793665362 1.5045005084507936 1.677097750809434 1.2707976882968026 1.0712335973864853 1.4686537285027084 1.0 15.616714675207927 -7.365678049197384 5.010426131136667 1.1980954325939122 1.5812996162079522 0.6120024931485036 0.1524285263264952 0.1586448484594154 6.1369727636064395 0.06283885812692125 0.04163239074090584 4.3084588642726826e-08 7.365678049197384 0.3832041836140401 S(ph)TGDIAGTVVPETNKEPR ddPTM_PC-9_AZD4547_30min_R2 5 STGDIAGTVVPETNKEPR 18 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(0.927)T(0.073)GDIAGTVVPETNKEPR;S(0.961)T(0.039)GDIAGTVVPETNKEPR;S(0.81)T(0.19)GDIAGTVVPETNKEPR;S(0.957)T(0.043)GDIAGTVVPETNKEPR;S(0.804)T(0.196)GDIAGTVVPETNKEPR 131.9 1.9095e-05 78717800.0 123040.7 153690.0 184346.0 160428.0 171653.0 241935.0 210117.0 239205.0 221847.0 212175.0 True False 162165.08319445307 203367.28692824297 181901.45159046355 123443.80318789222 147821.94389645683 226806.76620419518 228817.00594943552 202241.3636340663 233573.37951037305 204746.81783104347 0.7920273678112607 0.9932622596169535 0.8884213855795705 0.6029095079258214 0.7219743166823677 1.1077425701011652 1.1175607434263262 0.9877631592836541 1.140791256170424 1.0 17.643481504153897 -6.767677697980241 24.993135520209066 1.0729311076114876 0.8044654186295621 0.6238618992231926 0.10519427483237893 112.12197740320252 449201.5434494545 0.040248774920439045 0.036372388269542553 1.7073489901495352e-07 6.767677697980241 -0.26846568898192547 S(ph)TGDIAGTVVPETNKEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STGDIAGTVVPETNKEPR 18 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(0.833)T(0.167)GDIAGTVVPETNKEPR;S(0.954)T(0.046)GDIAGTVVPETNKEPR;S(0.975)T(0.025)GDIAGTVVPETNKEPR;S(0.782)T(0.218)GDIAGTVVPETNKEPR 213.01 1.1598e-27 58805600.0 70902.6 110654.0 137030.0 146149.0 163493.0 131328.0 154216.0 110520.0 131403.0 118785.0 True False 82905.00978981658 121638.99783319053 140297.3148891689 137960.74535145125 131457.72029432043 124440.92849026907 139607.54405284737 107618.96710561957 133324.5202849473 140319.7801984575 0.5908291024441609 0.8668699285386114 0.9998398991984107 0.983188151779672 0.9368438299176121 0.8868381087418281 0.9949241928358011 0.766955071860942 0.9501477275433539 1.0 17.09835886744866 -4.781997784018499 3.471196021942735 0.9332386167257493 0.5488694605717997 0.7049464147573691 0.06746785194416899 0.16198067113756937 3.193284050579174 0.017125825129043662 0.16537408501492162 1.6519702273624204e-05 4.781997784018499 -0.3843691561539495 S(ph)TGDIAGTVVPETNKEPR ddPTM_PC-9_Lapatinib_30min_R1 5 STGDIAGTVVPETNKEPR 18 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(0.956)T(0.044)GDIAGTVVPETNKEPR;S(0.79)T(0.21)GDIAGTVVPETNKEPR;S(0.843)T(0.157)GDIAGTVVPETNKEPR;S(0.811)T(0.189)GDIAGTVVPETNKEPR;S(0.826)T(0.174)GDIAGTVVPETNKEPR 144.08 2.0496999999999997e-05 96835200.0 219565.0 218954.0 244325.0 232007.0 284316.0 257236.0 228418.0 221667.0 283952.0 191044.0 True False 216433.96283671077 218447.02546549364 224237.54162177444 249069.5687326642 267593.09186676284 246234.61592640355 240244.36638214247 231966.45805516868 251970.3356128808 224065.70084987182 0.9659397311404012 0.9749239827288747 1.0007669213594532 1.1115916795295029 1.1942617315001514 1.0989393512369183 1.072205007151499 1.0352608952433577 1.12453773450005 1.0 17.773562297756527 -5.665496387935682 4.477944675731074 1.0962065768869054 0.974638563030111 0.5141408321907114 0.04942450776821774 0.17046577752278488 5.990476562429986 0.014244426401472287 0.025263953073160303 2.160248001667258e-06 5.665496387935682 -0.12156801385679439 S(ph)TGPTQETQAPFIAK ddPTM_PC-9_Lapatinib_30min_R1 1 STGPTQETQAPFIAK 15 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-4 O15231-7;O15231-4 ZNF185 Zinc finger protein 185 1 S(0.849)T(0.017)GPT(0.017)QET(0.117)QAPFIAK 76.58800000000001 0.013793000000000001 2779700.0 10665.0 12517.0 15847.0 13885.0 16235.0 17202.0 13976.0 12093.0 15753.0 11583.0 True False 10512.915144278533 12488.017655542188 14544.12083118899 14906.149219002165 15280.08921923808 16466.310559820555 14699.608894906805 12654.884927666968 13978.731253555927 13585.106116622652 0.7738559459182285 0.9192432910230952 1.0705930970530215 1.0972420157074145 1.124767748449271 1.2120855309089178 1.0820385773005081 0.9315263950851682 1.0289747561450138 1.0 13.729738214401007 -4.978837908525534 2.15715359483183 1.0757661197959485 0.7508858862114779 0.6361277737217259 0.07115219465356219 0.3040284356627866 2.201965036571544 0.02162451688197619 0.16468476141956864 1.0499342218665109e-05 4.978837908525534 -0.3248802335844706 S(ph)TGQLELGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STGQLELGR 9 0 E7EUN2 E7EUN2 AGAP1 1 S(0.986)T(0.014)GQLELGR;S(0.973)T(0.027)GQLELGR 101.53 0.0034680999999999996 19520700.0 24254.0 30699.0 34419.0 30198.0 45440.0 47736.0 34990.0 51690.0 47340.0 32663.0 True False 28359.723161664253 33746.593837377004 35239.679494784374 28506.103963236957 36536.358193769345 45232.64012557474 31675.493894337334 50333.19227008208 48032.257941518954 38584.54333983425 0.7350021720326023 0.8746143122688561 0.9133107831395098 0.7387959399225953 0.9469169525209754 1.1722994808358163 0.8209373793893242 1.3044910711206643 1.2448574943202966 1.0 15.235735410648408 -6.814056771731814 0.9294181912477444 1.1595047333579558 0.8126720018697436 0.4780670996121903 0.13947901379854674 0.4916789562573748 0.911910008711674 0.08683275805769322 0.07575011313335842 1.5344163881032134e-07 6.814056771731814 -0.34683273148821214 S(ph)TGSLLTPTR ddPTM_PC-9_AZD4547_30min_R2 2 STGSLLTPTR 10 0 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 S(0.968)T(0.018)GS(0.013)LLTPTR;S(0.994)T(0.006)GSLLTPTR 111.86 0.0015352 14456600.0 39808.0 34293.0 51839.0 71913.0 66729.0 56934.0 49757.0 74384.0 60871.0 62019.0 True False 52466.11594216227 45377.54161383463 51151.58098899909 55334.568894774566 57464.83017638289 53373.90797970378 54185.27660791878 62889.66197427466 64088.516789390575 59847.73368711445 0.8766600288735498 0.7582165408479732 0.8546953716981318 0.9245892114155094 0.9601838973019523 0.8918283900062781 0.9053856055970448 1.0508277941327486 1.0708595437288746 1.0 15.869008995803158 -6.633693819016483 0.48180950744611273 1.043729484625274 0.7996335560527463 0.6472352904109685 0.053244653365652816 0.7661493660427635 0.37106345501463617 0.05220195619947025 0.08136763149927767 2.3243749212200233e-07 6.633693819016483 -0.2440959285725277 S(ph)TGSLLTPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STGSLLTPTR 10 0 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 S(0.951)T(0.047)GS(0.003)LLTPTR;S(0.943)T(0.03)GS(0.027)LLTPTR 99.539 0.0043347 11665700.0 39218.0 48344.0 55020.0 55760.0 73039.0 53707.0 53752.0 45858.0 58521.0 44103.0 True False 45856.83280919224 53143.2728256345 56331.885464511986 52635.94797635907 58727.532264848516 50890.51037422998 48660.221429220364 44654.27609056734 59376.75891414513 52098.52478084408 0.8801944585205063 1.0200533133939054 1.081256824477772 1.010315516567421 1.127239830914403 0.9768128865127047 0.9340038251354108 0.8571121020875069 1.1397013478580713 1.0 15.668954901352802 -6.968002781843823 24.999717048854418 0.968598472087165 1.02864291653813 0.0435073267308691 0.08878313169773401 489.06456207523667 382109.1860063836 0.031024001681243665 0.02736042494012003 1.0764583184270656e-07 6.968002781843823 0.06004444445096491 S(ph)TGSLLTPTR ddPTM_PC-9_Lapatinib_30min_R1 2 STGSLLTPTR 10 0 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 S(0.968)T(0.03)GS(0.002)LLTPTR;S(0.949)T(0.021)GS(0.03)LLTPTR 98.156 0.004868 15168500.0 37943.0 51245.0 48344.0 48057.0 61278.0 60481.0 55878.0 50241.0 69078.0 44101.0 True False 37401.92586210601 51126.34535098339 44369.34293323662 51591.27209345244 57673.7485171833 57894.36861809711 58771.0894268462 52575.380273787814 61297.7082164118 51723.79908911129 0.7231086370447937 0.988449152060571 0.8578129161934877 0.9974377946323987 1.1150331091848311 1.1192984590778992 1.136248505752519 1.016464010758556 1.1850967890198145 1.0 15.658540623872598 -5.951569332008476 2.4348435777274693 1.0997960395268414 0.8649241760260413 0.6451277516750463 0.0789526983708941 0.17780235751064344 2.132862058334298 0.022972642326303198 0.036381654730462225 1.1179713342081432e-06 5.951569332008476 -0.23487186350080003 S(ph)TGSPTQETQAPFIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STGSPTQETQAPFIAK 16 0 O15231-3;O15231-2 O15231-3 ZNF185 Zinc finger protein 185 1 S(0.25)T(0.25)GS(0.25)PT(0.25)QET(0.001)QAPFIAK 60.56399999999999 0.025488999999999998 5997700.0 25272.0 22320.0 21793.0 32683.0 21997.0 23788.0 22304.0 28271.0 21071.0 19518.0 True False 29550.050455247754 24535.78209225887 22312.627770412753 30851.87746971563 17686.845756785744 22540.515403619316 20191.20365302372 27528.91620560052 21379.123512584385 23056.458895597007 1.2816387195039218 1.0641609018696432 0.9677387092028126 1.3381012934127225 0.7671102417276803 0.977622604827829 0.8757287380708556 1.1939784999186323 0.9272509542507009 1.0 14.492883334601085 -1.5228794035579172 0.7063000213055018 0.992901965380224 36.2617332112474 0.23385651839838995 0.1506987574248733 462.23619143760703 2.3931269598774123 0.05817926683367874 25771.900082067554 0.029999954527830205 1.5228794035579172 35.268831245867176 S(ph)TLSPPEASPGPPAAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STLSPPEASPGPPAAPR 17 0 Q6NUJ5-2;Q6NUJ5 Q6NUJ5-2 PWWP2B PWWP domain-containing protein 2B 1 S(0.886)T(0.105)LS(0.009)PPEASPGPPAAPR 143.64 2.3699e-08 0.0 14994.0 12332.0 13604.0 17130.0 19454.0 17147.0 13945.0 13916.0 14845.0 10515.0 True False 17532.18805500099 13556.239460651259 13928.370953457299 16170.261636209316 15642.128351707493 16247.781134431663 12624.028646942954 13550.719745220793 15062.080041019193 12421.286263305794 1.4114631676103875 1.0913716319942062 1.121330807309678 1.3018186114894168 1.2593002061241045 1.3080594706548119 1.0163221730293817 1.0909272564832115 1.212602279806937 1.0 13.600526956457939 -8.29127001344217 0.42599819930598765 1.0007904605407787 1.24427794377217 0.2908599395665098 0.10998080872136946 1.5874843930785743 0.7967335994401991 0.14806725467673135 0.08909649993823075 5.113638070158194e-09 8.29127001344217 0.24348748323139136 S(ph)TLTPTQR ddPTM_PC-9_AZD4547_30min_R2 1 STLTPTQR 8 0 O75376-2;O75376;A0A088AWL3;E7EVK1 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 S(0.917)T(0.013)LT(0.064)PT(0.006)QR 81.95 0.017159 2369600.0 20626.0 14596.0 19844.0 38922.0 23416.0 20901.0 21494.0 29979.0 24272.0 21693.0 True False 27184.638952548186 19313.871559663217 19580.855594160737 29949.134238905535 20165.092589581498 19594.057165907685 23406.924360604655 25346.43439888655 25554.9683677299 20933.53467283531 1.2986167590619422 0.922628302458931 0.9353821941771785 1.4306773656227987 0.9632913363527187 0.9360128364434404 1.1181544219084498 1.210805284201607 1.2207670021867667 1.0 14.353528313905585 -7.522731418678542 23.792697815813614 1.1623676945796626 1.0735822081404487 0.023254659809083922 0.16830127212685553 10.24204136088208 1655919.9470843223 0.07856303413057283 0.04606609269294281 3.0010178687483716e-08 7.522731418678542 -0.08878548643921391 S(ph)TMELVLDMPDVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STMELVLDMPDVVR 14 0 Q8NAT2;Q8NAT2-1 Q8NAT2 TDRD5 Tudor domain-containing protein 5 1 S(0.5)T(0.5)MELVLDMPDVVR 53.168 0.043487 3358000.0 28497.0 28383.0 26636.0 34470.0 33938.0 30781.0 32874.0 31358.0 23379.0 19475.0 True False 33320.97925859431 31200.67666328778 27271.10325759254 32538.757653247798 27288.092525971475 29166.790173146397 29759.936732850696 30534.88572654739 23720.87364627737 23005.66333598483 1.4483815907396393 1.3562172151969438 1.1854082561895019 1.414380327923497 1.186146738194164 1.2678091366974191 1.2935917690450167 1.3272769091941614 1.0310884454774154 1.0 14.489701434675192 -13.958246973348391 0.0684601352437068 1.7504683922745396e-13 1.6812639061192771 0.572453909786298 0.09350762080784458 220.658908208336 1.2048103001130541 36.22367491887185 5.598196838371791 1.1009130673875206e-14 13.958246973348391 1.6812639061191021 S(ph)TMLPAAVRCSES(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 STMLPAAVRCSESR 14 1 E9PDM8;O94855;O94855-2 E9PDM8 SEC24D Protein transport protein Sec24D 2 S(0.75)T(0.25)MLPAAVRCS(0.1)ES(0.9)R 100.69 0.013387 0.0 15543.0 25732.0 21040.0 15635.0 15103.0 19029.0 21386.0 26202.0 18628.0 12102.0 True False 20485.350685516172 34049.36578331418 20760.995852708205 12030.59230834202 13006.20914675646 17839.113621839013 23289.312569828384 22153.082962060973 19612.638050184287 11678.312663562121 1.7541361732361538 2.91560662607987 1.7777393405029527 1.030165286281387 1.1137061938183546 1.5275420461638611 1.9942360887882473 1.8969421011634258 1.6794068300104954 1.0 13.511544221595884 -5.510266589053535 24.470234830003225 1.5025510020557657 2.337821970003744 0.40629677840004663 0.4160085788673278 441.0720082797831 855770.4000115419 0.1145483419206294 0.22093083131845268 3.0883990553633822e-06 5.510266589053535 0.8352709679479782 S(ph)TNTAVSR ddPTM_PC-9_AZD4547_30min_R2 3 STNTAVSR 8 0 Q9NWB6-2;Q9NWB6 Q9NWB6-2 ARGLU1 Arginine and glutamate-rich protein 1 1 S(0.955)T(0.045)NTAVSR;S(0.954)T(0.046)NTAVSR;S(0.956)T(0.044)NTAVSR 147.28 0.0011044 53231900.0 30064.0 33757.3 29141.8 17460.0 20696.7 40977.9 34799.2 32750.1 45761.9 36153.4 True False 39623.7266299529 44668.68706501911 28755.36069108614 13434.866754310948 17823.320456046775 38415.54543509154 37896.26138501692 27689.324567429707 48180.78060922955 34887.68047023851 1.1357512478869023 1.2803570332835523 0.8242267844552279 0.3850891367160902 0.5108771983637961 1.1011206511095666 1.0862361978276236 0.7936705505844828 1.3810256216469 1.0 15.09043006176719 S(ph)TNTAVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STNTAVSR 8 0 Q9NWB6-2;Q9NWB6 Q9NWB6-2 ARGLU1 Arginine and glutamate-rich protein 1 1 S(0.954)T(0.046)NTAVSR;S(0.984)T(0.016)NTAVSR;S(0.953)T(0.046)NT(0.001)AVSR;S(0.965)T(0.034)NTAVSR 142.19 0.0020674 72128000.0 20171.1 57281.0 45588.9 29899.800000000003 67697.0 39310.7 32800.4 15844.4 37928.399999999994 49742.8 True False 23585.66883261506 62967.479123059136 46675.91227286602 28224.611142459496 54432.258816980735 37249.1776894677 29693.308657668542 15428.501288529491 38483.03109651681 58760.775876211876 0.40138457127083726 1.0715903284822055 0.7943379163541956 0.48033081118463694 0.9263366251604678 0.6339122847516261 0.5053253333519935 0.2625646285037467 0.6549101934526343 1.0 15.842565824888387 -5.728882671918526 24.403502292030716 0.613261586745245 0.7873531678434743 0.033889647969672754 0.25136908360551385 389.3619645727872 291849.84880562907 0.06770173674832645 0.11724989436775064 1.8668839761517449e-06 5.728882671918526 0.1740915810982293 S(ph)TNTAVSR ddPTM_PC-9_Lapatinib_30min_R1 4 STNTAVSR 8 0 Q9NWB6-2;Q9NWB6 Q9NWB6-2 ARGLU1 Arginine and glutamate-rich protein 1 1 S(0.961)T(0.039)NTAVSR;S(0.958)T(0.042)NTAVSR;S(0.98)T(0.02)NTAVSR;S(0.984)T(0.016)NTAVSR 133.91 0.0034773000000000004 92465700.0 33243.899999999994 46585.0 27708.5 33372.8 40118.0 31763.5 48980.1 44764.0 38055.2 28807.1 True False 32769.83588981539 46477.13529467387 25430.414087903093 35827.14704039723 37758.33811502268 30405.049149334947 51516.04991653008 46843.898859016284 33769.02263697846 33786.36885195204 0.9699129265239784 1.3756179451639596 0.7526826632165247 1.0604024125051037 1.1175612946296583 0.8999205946802499 1.5247584060384665 1.3864733160370337 0.9994865913217964 1.0 15.044153686524098 -7.238857158422762 24.99457083874355 1.2598857628715245 1.037934455570243 0.1671667344981861 0.21152991749948405 1286.2764496855839 1423685.05302948 0.07946227011969009 0.06150284399245536 5.769561959006404e-08 7.238857158422762 -0.22195130730128154 S(ph)TNTAVSRR ddPTM_PC-9_Lapatinib_30min_R1 1 STNTAVSRR 9 1 Q9NWB6-2;Q9NWB6 Q9NWB6-2 ARGLU1 Arginine and glutamate-rich protein 1 1 S(0.576)T(0.13)NT(0.291)AVS(0.003)RR 77.74 0.010369 1025700.0 12664.0 836.88 2233.1 1007.4 422.26 737.9 572.84 979.54 1062.3 496.38 True False 12483.409037706822 834.9422557777543 2049.5031380152814 1081.4875565878851 397.4234969951016 706.3417371289141 602.4988522723534 1025.0530043865797 942.6525874850801 582.1786216152252 21.442575481511557 1.4341685262527317 3.520402608273451 1.8576559090874076 0.6826487305433342 1.2132732307641332 1.0349037733483766 1.7607190754319042 1.6191810425290747 1.0 9.185318052498923 -4.761135799872767 24.999999963881734 1.6074506491267542 21.442597591891765 0.9848082363627744 0.7404789907729955 0.8281151281940117 68086.91835005973 0.19811740356639182 1.123378400059086 1.733261938012726e-05 4.761135799872767 19.83514694276501 S(ph)TPAMMNGQGSTTSSSK ddPTM_PC-9_AZD4547_30min_R2 3 STPAMMNGQGSTTSSSK 17 0 Q6ZN18-2;Q6ZN18;F5GZR7;A0A669KBC9;A0A669KBL4;G5EA50;Q6ZN18-3 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 S(0.5)T(0.5)PAMMNGQGSTTSSSK;S(0.565)T(0.435)PAMMNGQGSTTSSSK;S(0.5)T(0.5)PAMMNGQGSTTSSSK 118.31 6.8348e-05 6106700.0 10805.1 9695.7 11792.5 14113.7 18354.0 15468.2 12636.900000000001 15555.8 12372.8 11861.8 True False 14240.897039958225 12829.645415252566 11636.123744917377 10860.004519491322 15805.863913101242 14500.971008740886 13761.559619080903 13152.008546722695 13026.80094842818 11446.521992450922 1.2441243767626722 1.1208335094025788 1.0165641364766955 0.9487602021516742 1.3808442357884205 1.26684516207669 1.202248126387803 1.1489960492275781 1.138057565173025 1.0 13.48262168385623 -4.752360702859565 23.55379490531015 1.1448032770805718 1.244124789541517 0.06133814567203044 0.12263493009064386 625.851751223533 1623457.8023812498 0.03265519539690289 0.3703527463580172 1.7686394063955742e-05 4.752360702859565 0.09932151246094523 S(ph)TPAMMNGQGSTTSSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STPAMMNGQGSTTSSSK 17 0 Q6ZN18-2;Q6ZN18;F5GZR7;A0A669KBC9;A0A669KBL4;G5EA50;Q6ZN18-3 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 S(0.5)T(0.5)PAMMNGQGSTTSSSK;S(0.5)T(0.5)PAMMNGQGSTTSSSK 91.45700000000001 0.0013227 3896300.0 11691.7 12648.5 12564.0 15084.099999999999 17116.6 14466.7 15889.8 13277.3 16505.5 13478.599999999999 True False 13670.873888399032 13904.159488975632 12863.573409235341 14238.986780312016 13762.725102541208 13708.040784830157 14384.603111810264 12928.784943462202 16746.86171216182 15922.163483461105 0.8586065519676038 0.8732581789791543 0.8079036132619273 0.8942871862295936 0.8643753166356457 0.8609408387917362 0.9034326978712436 0.8119992585738598 1.0517956136775857 1.0 13.95874876033021 -8.26632798139739 24.999992754297438 1.0258978291008185 0.8609536243923012 0.8215363587123128 0.031042632357496033 160.10322722269936 818742.1897000367 0.025246545304133727 0.007325294523069618 5.415917230998321e-09 8.26632798139739 -0.16494420470851734 S(ph)TPAMMNGQGSTTSSSK ddPTM_PC-9_Lapatinib_30min_R1 2 STPAMMNGQGSTTSSSK 17 0 Q6ZN18-2;Q6ZN18;F5GZR7;A0A669KBC9;A0A669KBL4;G5EA50;Q6ZN18-3 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 S(0.5)T(0.5)PAMMNGQGSTTSSSK;S(0.676)T(0.324)PAMMNGQGSTTSSSK 114.54 0.0013761 0.0 4628.200000000001 6014.799999999999 7804.2 5148.0 7540.6 6112.1 5881.1 5749.0 7000.9 4717.1 True False 4562.201019292066 6000.873100148214 7162.568801083178 5526.601093224569 7097.076733390002 5850.699731000997 6185.594581556697 6016.119527756341 6212.384919254728 5532.444449859345 0.824626629447324 1.084669381596914 1.2946481191085935 0.9989438020231862 1.2828103016145849 1.0575252556127779 1.1180581454756329 1.0874252027798115 1.1229005506621343 1.0 12.433701344955923 -4.777639039530312 4.575424388380205 1.1263975536995656 0.8048644440897458 0.4573973812853179 0.09568908592291807 0.15035773492132748 7.045477666028559 0.02215505215172217 0.1539370920814873 1.6686335080862375e-05 4.777639039530312 -0.32153310960981984 S(ph)TPDLLR ddPTM_PC-9_AZD4547_30min_R2 4 STPDLLR 7 0 Q9P2M7-2;Q9P2M7;H0Y4A8 Q9P2M7-2 CGN Cingulin 1 S(0.987)T(0.013)PDLLR;S(0.987)T(0.013)PDLLR;S(0.98)T(0.02)PDLLR;S(0.991)T(0.009)PDLLR 141.48 0.0023818000000000003 25852500.0 63797.0 76274.0 121178.0 138889.0 122537.0 139089.0 140044.0 168552.0 144564.0 137648.0 True False 84083.11893996502 100928.07888063513 119571.10054370126 106870.2868636595 105524.85269258387 130391.74284239658 152507.64469882348 142506.1613396423 152205.3579067447 132828.9854167904 0.6330178513080503 0.759834749651541 0.9001883148358877 0.8045705274968578 0.7944414568963866 0.981651274631465 1.1481503394781298 1.0728543991545736 1.1458745802292711 1.0 17.01921047469203 -6.894471639354568 2.8285037079034963 1.0971500391592985 0.7827755565946107 0.8064957062189296 0.07281038687095222 0.11829312692529452 1.9115723851041173 0.029153084748970676 0.0250834021626052 1.2750533617789775e-07 6.894471639354568 -0.3143744825646878 S(ph)TPDLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 STPDLLR 7 0 Q9P2M7-2;Q9P2M7;H0Y4A8 Q9P2M7-2 CGN Cingulin 1 S(0.985)T(0.015)PDLLR;S(0.979)T(0.021)PDLLR;S(0.991)T(0.009)PDLLR;S(0.996)T(0.004)PDLLR;S(0.995)T(0.005)PDLLR 141.48 0.0023818000000000003 21854500.0 59705.1 77175.4 110732.0 120403.0 146546.0 120187.0 131911.0 116134.0 109506.0 86809.3 True False 69811.9942005229 84836.86367754976 113372.27083344838 113657.21026179302 117831.36328926313 113884.18214287846 119415.43512706268 113085.60555414435 111107.31808500167 102547.13890795942 0.6807795414280864 0.8272962520553068 1.1055624958508592 1.1083411148487075 1.1490458392507856 1.11055445676641 1.1644930945781267 1.1027670470225763 1.0834755534693696 1.0 16.645927715246486 -5.116211599950644 2.5229966505488925 1.1136083710354034 0.6836508769239742 0.9150712534894521 0.0434790960307281 0.07465624034235259 0.8585730849444099 0.011177763052559114 0.04926086964245574 7.652236785136714e-06 5.116211599950644 -0.42995749411142925 S(ph)TPDLLR ddPTM_PC-9_Lapatinib_30min_R1 4 STPDLLR 7 0 Q9P2M7-2;Q9P2M7;H0Y4A8 Q9P2M7-2 CGN Cingulin 1 S(0.988)T(0.012)PDLLR;S(0.995)T(0.005)PDLLR;S(0.987)T(0.013)PDLLR;S(0.971)T(0.029)PDLLR 146.81 0.0014315999999999999 18543500.0 97810.0 114446.0 122511.0 105902.0 115305.0 110378.0 108073.0 102387.0 116188.0 83525.0 True False 96415.21146384282 114181.00731854119 112438.61848613586 113690.38635871567 108522.9865983521 105657.3902436851 113668.49113474964 107144.27380212024 103101.68392611916 97962.18495993332 0.9842084627172901 1.1655620723980522 1.1477757313408579 1.160553803543839 1.1078048804519638 1.0785528138934337 1.1603302966470197 1.0937309518559881 1.0524641112107485 1.0 16.579937331847688 -8.416742481356213 2.029779114810265 1.0016423246272614 1.1185347407519213 0.3322897451098571 0.05159916476956687 0.33742823563329233 2.9142767302001547 0.047958040432416145 0.013540525112075945 3.830518098508448e-09 8.416742481356213 0.11689241612465984 S(ph)TPDSTYSESFK ddPTM_PC-9_AZD4547_30min_R2 2 STPDSTYSESFK 12 0 Q6ISB3-2;Q6ISB3 Q6ISB3-2 GRHL2 Grainyhead-like protein 2 homolog 1 S(0.651)T(0.349)PDSTYSESFK;S(0.655)T(0.345)PDSTYSESFK 196.27 1.2707e-05 65757000.0 186936.0 240430.0 217200.0 156218.0 220150.0 265140.0 248230.0 269950.0 255640.0 210758.0 True False 246377.759489651 318144.29563509335 214319.78608404094 120204.3536440404 189585.97256561188 248560.75388587939 270321.98911477136 228235.43033388184 269152.6085005961 203379.42656974265 1.2114192848565408 1.5642894711673094 1.0537928525948845 0.5910349717837368 0.9321787152379412 1.2221528896908518 1.3291511028136016 1.122214936797531 1.3234013540120715 1.0 17.63381422105111 -5.281516084967837 24.135067687968647 1.0685182932904163 1.387854368828003 0.25247777288111106 0.21751571646749676 679.1258412628789 816405.7673473665 0.06285129664741748 0.13114532090324513 5.229785962614401e-06 5.281516084967837 0.3193360755375867 S(ph)TPDSTYSESFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STPDSTYSESFK 12 0 Q6ISB3-2;Q6ISB3 Q6ISB3-2 GRHL2 Grainyhead-like protein 2 homolog 1 S(0.999)T(0.001)PDSTYSESFK;S(0.934)T(0.066)PDSTYSESFK 213.84 1.0768999999999999e-10 24872000.0 77262.0 118491.0 90377.0 84558.0 89291.0 67655.0 85536.0 48079.0 53128.0 61463.0 True False 90340.93060594136 130254.00340026154 92531.93043668116 79820.48940073488 71795.06953080685 64107.052700179316 77433.4108529876 46816.977193911334 53904.89649169874 72605.75535915974 1.244266796193371 1.793990059822841 1.274443464969855 1.0993686245103564 0.9888344136860411 0.8829472592504576 1.066491361049091 0.6448108274932373 0.7424328309105354 1.0 16.147796292770707 -5.867593357339918 1.3479803319114878 0.8606799476033659 1.5326067462081503 0.6759996532297328 0.17373728973814145 0.2452976057707439 0.9018541669821855 0.06016985400907287 0.12839406071404866 1.356458910183117e-06 5.867593357339918 0.6719267986047844 S(ph)TPDSTYSESFK ddPTM_PC-9_Lapatinib_30min_R1 1 STPDSTYSESFK 12 0 Q6ISB3-2;Q6ISB3 Q6ISB3-2 GRHL2 Grainyhead-like protein 2 homolog 1 S(0.999)T(0.001)PDSTYSESFK 207.34 6.0959e-08 45818000.0 112460.0 193300.0 178310.0 161190.0 215990.0 174060.0 216810.0 212710.0 153360.0 155870.0 True False 110856.29977736162 192852.4257263166 163650.0400965046 173044.45031407723 203285.89285267852 166615.85955367767 228035.36094052234 222593.28313603296 136086.981847606 182811.9218162804 0.6063953525348764 1.0549225882550841 0.8951825377174646 0.9465709270754281 1.1119947256884797 0.9114058749468253 1.2473768596431578 1.217608134767772 0.744409776427867 1.0 17.480000631180673 -4.758722077913597 24.995877686683418 1.022454809798873 0.6063947964287514 0.4155831551173551 0.14486132920201014 73.51404121481066 676109.1099105809 0.03596630484742222 0.2410426004102308 1.7429218807117548e-05 4.758722077913597 -0.41606001337012166 S(ph)TPDSTYSESFKDAATEK ddPTM_PC-9_AZD4547_30min_R2 2 STPDSTYSESFKDAATEK 18 1 Q6ISB3-2;Q6ISB3 Q6ISB3-2 GRHL2 Grainyhead-like protein 2 homolog 1 S(0.474)T(0.474)PDS(0.031)T(0.007)Y(0.006)S(0.007)ESFKDAATEK;S(0.786)T(0.203)PDS(0.006)T(0.001)Y(0.001)S(0.001)ESFKDAATEK 87.228 0.00078494 60031000.0 184477.0 128988.0 197661.0 276855.0 255351.0 247488.0 196756.0 222385.0 190883.0 238484.0 True False 243136.84864002853 170680.84850218138 195039.88599059696 213030.35711711095 219899.92132910076 232012.53623635988 214266.9028331221 188020.5081489168 200972.6856846322 230134.7477488803 1.0564977736666517 0.7416561391608096 0.8475029863956992 0.9256766272843187 0.955526809749966 1.0081595174385773 0.9310497651007793 0.817001821707003 0.8732826643976888 1.0 17.812119305109803 -4.45965941368158 16.5959857722539 0.8994883239605846 2.8149724122578914 0.2628020986826195 0.07863747404261653 1239291.7678813273 6922692.206499524 0.02070216081755809 81505319.78711794 3.470088781910528e-05 4.45965941368158 1.9154840882973068 S(ph)TPDSTYSESFKDAATEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STPDSTYSESFKDAATEK 18 1 Q6ISB3-2;Q6ISB3 Q6ISB3-2 GRHL2 Grainyhead-like protein 2 homolog 1 S(0.68)T(0.314)PDS(0.001)T(0.003)Y(0.001)S(0.001)ESFKDAATEK;S(0.819)T(0.18)PDS(0.001)TYSESFKDAATEK 102.59 0.00021448 39465000.0 153388.0 75101.0 95354.0 186459.0 170288.0 174040.0 155067.0 153744.0 153706.0 133050.0 True False 179353.55884890564 82556.53095478195 97627.60099205901 176012.30673823462 136921.28882263653 164913.0360200903 140377.9311721412 149708.38290523316 155953.659466817 157170.9117767797 1.1411371024151757 0.5252659669750595 0.6211556571658345 1.1198783842917077 0.8711617644433947 1.0492592691343947 0.8931546530156383 0.9525196565497748 0.9922552316061415 1.0 17.261974711635744 -5.757420224266103 24.99997364074631 0.9750325921711055 0.7387942216756138 0.2719469656668828 0.16331654786542787 124.20487570791495 772566.0357148111 0.04330960964705189 0.07163127731018312 1.7481543521263331e-06 5.757420224266103 -0.23623837049549168 S(ph)TPDSTYSESFKDAATEK ddPTM_PC-9_Lapatinib_30min_R1 1 STPDSTYSESFKDAATEK 18 1 Q6ISB3-2;Q6ISB3 Q6ISB3-2 GRHL2 Grainyhead-like protein 2 homolog 1 S(0.493)T(0.493)PDS(0.005)T(0.005)Y(0.001)S(0.001)ESFKDAATEK 118.19 4.8195e-05 27771000.0 196120.0 117780.0 124640.0 112940.0 102950.0 120750.0 74047.0 65743.0 125900.0 82596.0 True False 193323.29283599684 117507.28764638158 114392.58032431373 121245.98435679547 96894.68340748746 115585.80398199813 77880.79134524637 68797.6597866212 111719.81621422534 96872.60854774789 1.9956445452865967 1.2130083973991779 1.1808557861630242 1.251602348428907 1.0002278751452087 1.1931732376652853 0.8039505956615117 0.7101869229908397 1.1532652819930966 1.0 16.56380117007385 -1.5228787452864245 0.6981016859643308 0.9740495631263755 119.08126300075729 0.7627952575846115 0.16082181160895714 139.89012140103543 0.7480986833397998 0.06579753038235177 25780.214964682422 0.029999999999579526 1.5228787452864245 118.10721343763092 S(ph)TPEHTWSSR ddPTM_PC-9_AZD4547_30min_R2 1 STPEHTWSSR 10 0 O14646;O14646-2 O14646 CHD1 Chromodomain-helicase-DNA-binding protein 1 1 S(0.899)T(0.101)PEHTWSSR 97.163 0.0052513 6870100.0 14641.0 16806.0 29461.0 40970.0 34414.0 32868.0 23537.0 42912.0 31964.0 27509.0 True False 19296.53344828169 22238.210840757743 29070.327890524564 31524.999480190123 29636.210128880146 30812.75876412869 25631.747402789235 36280.93641966111 33653.55178420068 26545.91828308792 0.7269115064132204 0.837726184628747 1.095095960912564 1.1875648506111132 1.1164130700937556 1.1607343334496407 0.965562657484669 1.36672372877661 1.2677486393695767 1.0 14.696202427944334 -5.207609247582016 2.3214922864296814 1.1592916012089078 0.7297868026643748 0.6438257095662987 0.10994727940343973 0.20439646645178694 2.0278191525110363 0.03080360458671834 0.12036366102710282 6.19998662223066e-06 5.207609247582016 -0.42950479854453305 S(ph)TPGAPR ddPTM_PC-9_AZD4547_30min_R2 2 STPGAPR 7 0 Q92615;H0Y4V9;A0A087X183 Q92615 LARP4B La-related protein 4B 1 S(0.846)T(0.154)PGAPR;S(0.5)T(0.5)PGAPR 101.72 0.011108 8260800.0 59650.0 52359.0 58736.0 69160.0 72147.0 77750.0 57535.0 72581.0 80614.0 80664.0 True False 78617.45920292339 69283.02281394949 57957.12226257935 53216.23051134848 62130.63439787057 72888.28020904845 62655.50353993617 61365.27419545633 84875.09146325722 77839.97791221057 1.0099882002997185 0.8900699187259306 0.7445675579192034 0.6836619425993 0.7981841216340362 0.936386188229052 0.8049270467496825 0.7883516393679515 1.0903791822626285 1.0 16.24822368029092 -8.260481055484991 24.99658849147125 1.0451896081459837 0.8275402178943985 0.4645404400276204 0.09144571340299196 77.13620188168747 2012140.4826527343 0.07575711873864939 0.024847739552312818 5.48932500265823e-09 8.260481055484991 -0.21764939025158525 S(ph)TPGAPR ddPTM_PC-9_Lapatinib_30min_R1 2 STPGAPR 7 0 Q92615;H0Y4V9;A0A087X183 Q92615 LARP4B La-related protein 4B 1 S(0.5)T(0.5)PGAPR;S(0.586)T(0.414)PGAPR 89.698 0.016425 7784500.0 79944.0 107508.0 126333.0 98797.0 106866.0 81645.0 96115.0 81620.0 103708.0 69471.0 True False 78803.98390006588 107259.07183127162 115946.38839948275 106062.8609571306 100580.35198663983 78153.23367379072 101091.364405693 85412.36316845925 92027.31294634541 81478.969785711 0.9671696157587619 1.3164019146702772 1.4230222682542595 1.30172069229735 1.234433280773742 0.9591828895153321 1.2407049901534402 1.0482749523354682 1.1294609294689963 1.0 16.314140118635258 -6.593697176074403 8.887943539630404 1.0891107791336916 1.2687916730305149 0.3014930242534333 0.1300861330601528 0.38059006427244774 43.69916953748587 0.043122642064774654 0.0431120522279227 2.5486067201991956e-07 6.593697176074403 0.1796808938968233 S(ph)TPGSNSADGGR ddPTM_PC-9_Lapatinib_30min_R1 1 STPGSNSADGGR 12 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;H7C1R1;O15231-3 O15231-7;O15231-3 ZNF185 Zinc finger protein 185 1 S(0.974)T(0.026)PGSNSADGGR 123.95 0.00033685 7282400.0 25898.0 28863.0 36178.0 27987.0 28992.0 21886.0 24379.0 19804.0 24483.0 18276.0 True False 25528.689770888446 28796.169496837447 33203.584491118556 30045.257341895132 27286.747560465064 20949.98679875785 25641.225332636855 20724.16613805645 21725.46672258044 21434.982248760745 1.1909825478098717 1.3434193302633728 1.5490371816397566 1.4016926626394657 1.2730007071520966 0.9773736481619464 1.1962326366805969 0.966838502479031 1.0135518877715184 1.0 14.387679601946441 -6.610187478570332 3.9118974571981306 1.039485920854173 1.378705352674471 0.7180119368256178 0.10164917261218452 0.12854352445677064 3.7804684522053145 0.03636544621836328 0.03653700870839789 2.453649482467231e-07 6.610187478570332 0.3392194318202981 S(ph)TPKEDDSSASTSQSTR ddPTM_PC-9_Lapatinib_30min_R1 1 STPKEDDSSASTSQSTR 17 1 E7EX17;P23588-2;P23588;F8VX11 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 S(0.962)T(0.038)PKEDDSSASTSQSTR 86.756 0.014534 2881500.0 10387.0 8576.4 7336.2 9088.7 6679.9 6569.4 6107.4 6825.1 7068.7 5518.9 True False 10238.87947525749 8556.541872732447 6733.045954550941 9757.1133170144 6287.001415188695 6288.442076019367 6423.611288262289 7142.219062252529 6272.548569289073 6472.834511527996 1.5818231498151605 1.3219157476517291 1.0402005400508099 1.5073942180411326 0.9712903062779783 0.9715128765952181 0.9923954145316026 1.1034144391506335 0.9690574597755871 1.0 12.660181904177536 -1.5228787452803527 0.3804113843430899 0.988911827174889 9.165745115787809 0.6023785273995718 0.14123823368427102 48.35813831036227 0.6597969483055296 0.10942989939340207 291.58867157161876 0.029999999999998955 1.5228787452803527 8.17683328861292 S(ph)TPLEENVVDREQIDFLAAR ddPTM_PC-9_AZD4547_30min_R2 1 STPLEENVVDREQIDFLAAR 20 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 S(0.841)T(0.159)PLEENVVDREQIDFLAAR 65.949 0.0029287 2016700.0 1817.2 3654.6 3717.8 6979.1 6292.8 3796.4 2540.0 5061.7 4321.4 5747.2 True False 2395.031799891913 4835.87798040183 3668.499542832634 5370.1763210201325 5419.153341634708 3559.0105078537845 2766.0550793680027 4279.530571294711 4549.820381687048 5545.992277311534 0.4318491047472076 0.8719590180796397 0.6614685631352826 0.9682985573184697 0.9771296227375361 0.6417265531388451 0.49874845493093095 0.7716438028235497 0.820379862463965 1.0 12.43722989211555 -8.626597153414526 2.44921178249042 0.9990686037784238 0.7369227515088644 0.18898411078562705 0.17179202715873432 0.8047871545773604 10.618998457948944 0.17104407705726 0.046377343230389216 2.3626688015604383e-09 8.626597153414526 -0.26214585226955933 S(ph)TPLSQPSANGVQTEGLDYDR ddPTM_PC-9_AZD4547_30min_R2 5 STPLSQPSANGVQTEGLDYDR 21 0 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 1 S(0.632)T(0.364)PLS(0.002)QPS(0.001)ANGVQTEGLDYDR;S(0.829)T(0.16)PLS(0.005)QPS(0.003)ANGVQT(0.003)EGLDYDR;S(0.395)T(0.395)PLS(0.144)QPS(0.001)ANGVQT(0.065)EGLDYDR;S(0.833)T(0.166)PLS(0.001)QPSANGVQTEGLDYDR;S(0.786)T(0.179)PLS(0.029)QPS(0.005)ANGVQTEGLDYDR 221.05 1.5331e-32 62312800.0 35192.7 39715.299999999996 51432.9 70736.4 65069.899999999994 55254.4 43541.2 58245.700000000004 45522.700000000004 53657.3 True False 46383.246546365874 52552.49404997887 50750.866140340106 54429.21584648576 56036.067573232365 51799.33363321993 47416.28244951891 49245.16541803354 47928.936985566004 51778.77425901103 0.8957965345866377 1.0149427985123305 0.9801480793359639 1.0511878008972657 1.082220820696242 1.0003970618173783 0.9157474878090048 0.9510685821123591 0.9256483505347746 1.0 15.660073192771694 -7.158276498825587 6.511160520887061 0.9442866106931704 1.0097784807843284 0.22537098465061833 0.050201498304111 0.34369850377873906 18.55674860191227 0.019916769598394335 0.015387336143817164 6.945819627954637e-08 7.158276498825587 0.06549187009115798 S(ph)TPLSQPSANGVQTEGLDYDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 STPLSQPSANGVQTEGLDYDR 21 0 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 1 S(0.848)T(0.152)PLSQPSANGVQTEGLDYDR;S(0.834)T(0.166)PLSQPSANGVQTEGLDYDR;S(0.831)T(0.169)PLSQPSANGVQTEGLDYDR 235.35 3.320499999999999e-125 34359000.0 19626.7 25794.100000000002 23087.7 28635.800000000003 30849.8 27605.1 38206.0 23731.4 31010.7 21206.3 True False 22949.112665005174 28354.76778073181 23638.198328589828 27031.428964516217 24805.00314714227 26157.43995999882 34586.85109251365 23108.475895496744 31464.172821019452 25050.83432102158 0.9161017302225047 1.1318891585553985 0.9436092237755799 1.079063021139883 0.9901867071280329 1.0441744025287265 1.380666633665365 0.922463323950257 1.2560129701794434 1.0 14.61257103290031 -7.023834717658723 24.90792461942421 1.1446237897850804 1.0185735643333034 0.17497981246144678 0.13108029138302618 1250.2786734357685 1306571.1932883065 0.04616195893263714 0.03597709505356463 9.465973456741765e-08 7.023834717658723 -0.12605022545177702 S(ph)TPLSQPSANGVQTEGLDYDR ddPTM_PC-9_Lapatinib_30min_R1 4 STPLSQPSANGVQTEGLDYDR 21 0 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 1 S(0.5)T(0.5)PLSQPSANGVQTEGLDYDR;S(0.829)T(0.17)PLS(0.002)QPSANGVQTEGLDYDR;S(0.627)T(0.116)PLS(0.257)QPSANGVQTEGLDYDR;S(0.836)T(0.163)PLS(0.001)QPSANGVQTEGLDYDR 218.22 3.2032999999999996e-93 28100400.0 25379.100000000002 25270.100000000002 31362.3 25827.2 31613.0 31831.5 31603.2 27661.1 32612.699999999997 26266.8 True False 25017.18938004308 25211.58863604033 28783.812755978954 27726.61844501352 29753.585493549348 30470.140947850705 33239.45906035481 28946.3356878102 28939.51429904419 30806.981381689013 0.8120623397043614 0.818372573530542 0.9343275928062013 0.9000108806990615 0.9658065853616615 0.9890661006456635 1.0789586505905318 0.9396031155787065 0.9393816921071402 1.0 14.91096970655443 -5.407729697765458 0.8617700638189509 0.9897926907921254 0.7733586339359506 0.7062398004018355 0.04153471127385935 0.6370144103484868 0.6700452997289287 0.01773545690337385 0.10997091639242439 3.910842284967356e-06 5.407729697765458 -0.21643405685617478 S(ph)TPLSQPSANGVQTEGLDYDRLK ddPTM_PC-9_AZD4547_30min_R2 1 STPLSQPSANGVQTEGLDYDRLK 23 1 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 1 S(0.769)T(0.225)PLS(0.006)QPSANGVQTEGLDYDRLK 73.934 0.00021655 3933900.0 12327.0 16591.0 19711.0 30918.0 22615.0 20538.0 18599.0 20484.0 15934.0 23559.0 True False 16246.729582471708 21953.716295311893 19449.619261061387 23790.33277833826 19475.297613315062 19253.755613291818 20254.27496896277 17318.668475492585 16776.238710094283 22734.206580801514 0.7146380730168819 0.9656689014980304 0.8555222365880197 1.0464553796405025 0.8566517394876441 0.8469068645461834 0.8909162893798552 0.7617889990547451 0.7379293687012333 1.0 14.472577034746175 -7.130227904238823 1.647194013691714 0.8224200009398492 0.8974275720089616 0.018590445533237743 0.10473958285461386 1.0213183911551185 5.482768471273689 0.05290752399112366 0.03587340567494235 7.409213267928938e-08 7.130227904238823 0.07500757106911238 S(ph)TPPPNNLVNPVQELETER ddPTM_PC-9_AZD4547_30min_R2 1 STPPPNNLVNPVQELETER 19 0 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 S(0.773)T(0.227)PPPNNLVNPVQELETER 56.038999999999994 0.029575999999999998 4930000.0 15187.0 13940.0 17842.0 21671.0 19834.0 20603.0 16086.0 22269.0 15085.0 14340.0 True False 20016.150090776177 18445.832388442377 17605.40342224429 16675.085763612395 17080.391459760824 19314.691153016418 17517.622837288836 18827.837740711988 15882.36230336213 13837.960964756301 1.4464667259688775 1.332987745479395 1.2722541613669263 1.205024772513951 1.2343141813495948 1.3957758084596943 1.2659106989753919 1.360593355384101 1.1477386259299824 1.0 13.756343755851033 -8.506834920722417 3.547304827017176 1.0007859455550185 1.307632867900903 0.672289070518783 0.07065840490013658 0.12372813804586755 3.935185484358716 0.07076134320551054 0.01867110371832947 3.112899353575136e-09 8.506834920722417 0.3068469223458845 S(ph)TPPPNNLVNPVQELETER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 STPPPNNLVNPVQELETER 19 0 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 S(0.774)T(0.226)PPPNNLVNPVQELETER;S(0.5)T(0.5)PPPNNLVNPVQELETER;S(0.798)T(0.202)PPPNNLVNPVQELETER 68.26100000000001 0.0085736 14814400.0 38801.6 47713.0 50697.0 55960.0 60773.0 52962.5 56556.0 45181.0 48680.0 39779.4 True False 45369.94451346712 52449.631315768216 51905.80874944315 52824.74262476785 48864.96691263077 50185.053264847345 51198.6062500184 43995.046623226524 49391.852906488 46991.09032644285 0.9655009960034173 1.1161611903747153 1.1045883036307138 1.124143795298197 1.0398772740357858 1.0679695430818124 1.0895385890037093 0.9362423029045914 1.0510897398499859 1.0 15.520099622289601 -7.739295474191466 24.999551846888068 0.9952494876135857 1.0760030606844126 0.32839414890367036 0.050133231387699775 245.44136032866845 277093.54315131786 0.02299271498145261 0.013261613879037243 1.822655228756958e-08 7.739295474191466 0.08075357307082698 S(ph)TPPPNNLVNPVQELETER ddPTM_PC-9_Lapatinib_30min_R1 1 STPPPNNLVNPVQELETER 19 0 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 S(0.5)T(0.5)PPPNNLVNPVQELETER 66.78399999999999 0.009624299999999999 4747700.0 24342.0 18940.0 19809.0 25322.0 22494.0 23615.0 20572.0 22466.0 23652.0 22109.0 True False 23994.878616223923 18896.14559367012 18180.380484951278 27184.264351715745 21170.947144905545 22605.041499253704 21637.117500430937 23509.85237616522 20988.062693398384 25930.511191609286 0.9253530884492666 0.7287224480088391 0.7011192471529126 1.0483504991799835 0.8164492781675718 0.8717545648143006 0.8344269552014221 0.9066482416194188 0.8093964109812767 1.0 14.662363027172596 -14.522878745249503 0.18728133720902268 1.628482471435151 0.8204139904461898 0.17879015649410546 0.09464159436566234 239.4356237166695 2.3260012139058626 56.305876151012036 0.2678491853363828 3.000000000212995e-15 14.522878745249503 -0.8080684809889611 S(ph)TPPPNNLVNPVQELETERR ddPTM_PC-9_AZD4547_30min_R2 3 STPPPNNLVNPVQELETERR 20 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 S(0.5)T(0.5)PPPNNLVNPVQELETERR;S(0.5)T(0.5)PPPNNLVNPVQELETERR;S(0.5)T(0.5)PPPNNLVNPVQELETERR 104.82 6.9911e-05 32392400.0 24307.2 20545.9 25216.5 34493.0 32389.0 30465.6 21218.3 26941.300000000003 24387.1 31000.2 True False 32036.383978831564 27186.96037802714 24882.112733831604 26541.171761537655 27892.34642483579 28560.581215907227 23106.68759470633 22778.14113448489 25676.152318748602 29914.892433726527 1.070917572236136 0.9088102335068444 0.8317634030928058 0.8872227042212164 0.9323899956059849 0.9547278593489967 0.7724141962367708 0.7614314905175608 0.8583066904095198 1.0 14.868576254990645 -7.252219983110894 24.80299533839595 0.8281573841577112 0.92353098437491 0.17104424461353807 0.08410073280685472 916.8041172031576 2466487.5184792946 0.03245209317400501 0.024778274853797057 5.594741393684174e-08 7.252219983110894 0.09537360021719876 S(ph)TPPPNNLVNPVQELETERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STPPPNNLVNPVQELETERR 20 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 S(0.5)T(0.5)PPPNNLVNPVQELETERR;S(0.5)T(0.5)PPPNNLVNPVQELETERR;S(0.899)T(0.101)PPPNNLVNPVQELETERR;S(0.5)T(0.5)PPPNNLVNPVQELETERR 100.58 0.00014139 25720600.0 23025.300000000003 24290.199999999997 27759.300000000003 30007.9 34293.1 34378.3 26166.7 28444.9 27353.6 25443.5 True False 26923.02851959543 26701.570527660675 28421.1869897315 28326.65464992442 27573.613230078132 32575.441428461687 23688.000745497477 27698.25151486282 27753.594652072938 30056.205139364818 0.8957560808078914 0.8883879519670115 0.9456013112083826 0.9424561257344097 0.917401684684564 1.0838175104746477 0.7881234718641555 0.921548525052693 0.9233898465686163 1.0 14.875375247345735 -5.2568329486309135 23.368923291191734 0.9364415268191262 0.8920720063456881 0.06891703976380792 0.06975635560616313 484.1070957005647 2455858.419489162 0.01768966088550951 0.04342213226218765 5.5356299627182035e-06 5.2568329486309135 -0.04436952047343812 S(ph)TPPPNNLVNPVQELETERR ddPTM_PC-9_Lapatinib_30min_R1 2 STPPPNNLVNPVQELETERR 20 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 S(0.5)T(0.5)PPPNNLVNPVQELETERR;S(0.5)T(0.5)PPPNNLVNPVQELETERR 104.78 7.017e-05 25376000.0 50447.0 33711.0 46075.0 36506.0 43410.0 45491.0 37755.0 28216.0 43890.0 29127.0 True False 49727.6165291532 33632.94425069768 42286.891354643325 39190.773020446024 40856.709147343696 43545.45597470043 39709.76916336621 29527.01836757226 38946.64601781054 34161.56314071208 1.455659869085155 0.9845259162223633 1.2378500123212417 1.1472183769524402 1.195984767414014 1.274691553057333 1.162410777276232 0.8643345225729264 1.1400721289417763 1.0 15.060086369840356 -7.5932286501062265 8.466652550069487 1.0024850852974247 1.2037596570392342 0.3650145989684511 0.12609940640125478 0.2976411395050337 32.131564908545684 0.05540072552436384 0.031879802297885174 2.551357694057571e-08 7.5932286501062265 0.2012745717418094 S(ph)TPSHGSVSSLNSTGSLSPK ddPTM_PC-9_AZD4547_30min_R2 1 STPSHGSVSSLNSTGSLSPK 20 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;M0R2S2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 S(0.243)T(0.243)PS(0.218)HGS(0.218)VS(0.06)S(0.017)LNSTGSLSPK 57.00899999999999 0.011202 3918900.0 7046.0 4268.4 18310.0 39841.0 22098.0 16297.0 9930.2 23030.0 11562.0 12947.0 True False 9286.481434095536 5648.076826888628 18067.19743645852 30656.272987313994 19030.074139245462 15277.946013721723 10813.968562653587 19471.24267675232 12173.14371570918 12493.729470760094 0.743291381154787 0.4520729250707083 1.44610122051565 2.4537327352141656 1.523170017710309 1.2228491139877582 0.8655516823829295 1.5584812143021158 0.9743402675877366 1.0 13.608916575937506 -8.306941234563418 22.809786625614212 0.9871686173207227 1.2919744026291882 0.049295442722589566 0.5187818717287791 716.3461334451233 359085.4274456649 0.5531078369034981 0.14281727040275022 4.932405410100447e-09 8.306941234563418 0.30480578530846547 S(ph)TPSSSTPSSR ddPTM_PC-9_AZD4547_30min_R2 2 STPSSSTPSSR 11 0 H3BUV9;Q96S82 H3BUV9 UBL7 Ubiquitin-like protein 7 1 S(0.775)T(0.225)PSSSTPSSR;S(0.995)T(0.005)PSSSTPSSR 124.39 0.00051414 5859900.0 21197.8 26942.0 31299.0 27894.0 28005.0 37043.0 29697.0 37574.0 30602.0 31136.0 True False 27938.259458369354 35650.47462047452 30883.954809596704 21463.469258003977 24116.989151487418 34726.69535413227 32339.97546928802 31767.801664624025 32219.559244778764 30045.938117060832 0.9298514611033334 1.1865322520993709 1.0278911808069 0.7143551043199575 0.8026705326199547 1.1557866896628397 1.0763509977052297 1.0573076979941416 1.0723432604849736 1.0 14.874882347042877 -6.776981131294727 24.997212921132125 1.0761890237461584 0.9395933059629347 0.24413258615405165 0.12282601742674547 421.80950760225124 678430.2303065633 0.048604572423761566 0.043011913552797806 1.6711632194267676e-07 6.776981131294727 -0.13659571778322377 S(ph)TPSSSTPSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STPSSSTPSSR 11 0 H3BUV9;Q96S82 H3BUV9 UBL7 Ubiquitin-like protein 7 1 S(0.721)T(0.279)PSSSTPSSR;S(0.981)T(0.019)PSSSTPSSR 120.86 0.00082525 7154800.0 19451.1 27459.9 24965.3 24461.7 25604.0 18015.0 23703.5 15872.8 16497.3 14582.2 True False 22743.787053263266 30185.937395843142 25560.567433427485 23091.190254901438 20587.079999851896 17070.261686405 21458.132881521167 15456.15581862176 16738.541802674696 17225.83742736832 1.3203298329710262 1.7523640010606327 1.483850497324269 1.3404973982985744 1.1951279632503238 0.9909684657353064 1.2456946126420885 0.8972658591369905 0.9717113535554788 1.0 14.07228650024064 -6.21514679841021 1.2786746956729798 1.016437522320783 1.5565626200854568 0.7365063636522997 0.13042200667803602 0.2193592704190958 0.7293997098507995 0.05035576077858091 0.07543549673494908 6.093308989366138e-07 6.21514679841021 0.5401250977646737 S(ph)TQGVTLTDLQEAEK ddPTM_PC-9_AZD4547_30min_R2 2 STQGVTLTDLQEAEK 15 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 S(0.985)T(0.015)QGVTLTDLQEAEK;S(0.5)T(0.5)QGVTLTDLQEAEK 180.1 2.4556e-05 5363900.0 17284.5 15628.6 28673.0 27835.8 29351.0 24732.0 30428.6 25443.0 27269.6 25876.0 True False 22780.61146006591 20680.23931606964 28292.77728539462 21418.686368822957 25276.12028513862 23185.50413029179 33136.68645199101 21511.368971976073 28711.01538400821 24970.089116041414 0.9123159855056773 0.8282004609580722 1.1330667325179318 0.8577737255676454 1.012255910168162 0.92853109264223 1.327055193836019 0.8614854705567161 1.1498162962327407 1.0 14.60791334967587 S(ph)TQGVTLTDLQEAEK ddPTM_PC-9_Lapatinib_30min_R1 3 STQGVTLTDLQEAEK 15 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 S(0.638)T(0.362)QGVTLTDLQEAEK;S(0.573)T(0.427)QGVTLTDLQEAEK;S(0.99)T(0.01)QGVTLTDLQEAEK 236.27 1.3845999999999995e-108 5464000.0 42781.5 51289.8 45110.6 37553.7 45480.7 43023.3 53713.0 37209.5 34286.6 28993.5 True False 42171.427964833776 51171.04161933591 41401.7805999517 40315.524373470784 42805.61464449654 41183.29375121075 56493.99632027252 38938.389209958164 30424.882054095768 34004.98784358967 1.2401541844039676 1.5048098783244306 1.2175208175454888 1.1855767912315465 1.2588039978542704 1.2110956763354432 1.6613444057125957 1.1450787569476664 0.8947182158699465 1.0 15.053458755601737 -7.999643314554158 24.99998189919301 0.9715388224878406 1.322219563978464 0.5250275118637188 0.14415067783614535 9.312515180884201 652731.104707742 0.08063754336056643 0.03815011484375785 1.0008216359485227e-08 7.999643314554158 0.35068074149062334 S(ph)TQLLQAAAAEASLNK ddPTM_PC-9_AZD4547_30min_R2 4 STQLLQAAAAEASLNK 16 0 Q2M2I8;Q2M2I8-2 Q2M2I8 AAK1 AP2-associated protein kinase 1 1 S(0.845)T(0.155)QLLQAAAAEASLNK;S(0.937)T(0.063)QLLQAAAAEASLNK;S(0.961)T(0.039)QLLQAAAAEASLNK;S(0.978)T(0.022)QLLQAAAAEASLNK 192.6 4.1019e-09 14908800.0 39544.299999999996 51722.0 58536.0 71854.0 65576.0 64012.0 60919.0 78831.0 54492.5 56792.0 True False 52118.56482746299 68440.12502116336 57759.774393257074 55289.17043323362 56471.90432415418 60009.31952079247 66340.67298425958 66649.48030616839 57372.86230135636 54803.72936613943 0.951003981485693 1.2488224033791613 1.0539387567471648 1.0088578108225263 1.0304390773640568 1.094986056877168 1.2105138418782184 1.21614862851556 1.0468787975732958 1.0 15.741986450745584 -7.007401551498696 23.757980610493544 1.1387337404396178 1.065811499350839 0.06348830720729393 0.09494181333022692 412.96190568941535 1325556.114772328 0.03401602031668289 0.028782656075531515 9.831017031861778e-08 7.007401551498696 -0.07292224108877887 S(ph)TQLLQAAAAEASLNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STQLLQAAAAEASLNK 16 0 Q2M2I8;Q2M2I8-2 Q2M2I8 AAK1 AP2-associated protein kinase 1 1 S(0.758)T(0.242)QLLQAAAAEASLNK 83.404 0.005543899999999999 2171500.0 5564.1 6732.0 6716.9 9538.7 8271.4 7652.5 8297.8 7828.5 6816.6 5194.7 True False 6505.992234015669 7400.308469761948 6877.056369985106 9004.277563882652 6650.678546741718 7251.189428543671 7511.772313130386 7623.010169981388 6916.279879259782 6136.457988777429 1.0602194695888179 1.2059576523290623 1.1206882508707972 1.467341189388079 1.0837976172744461 1.1816571451812923 1.2241218512158285 1.2422492232363715 1.1270801318787678 1.0 12.58319044571033 -8.576212297820371 4.288537921285295 1.0000831547868576 1.2009657613113311 0.24560564633487258 0.10659907044761614 0.36974408263597475 20.90093893822011 0.09987250450039539 0.026095407079754305 2.6533082181791523e-09 8.576212297820371 0.20088260652447354 S(ph)TQLLQAAAAEASLNK ddPTM_PC-9_Lapatinib_30min_R1 2 STQLLQAAAAEASLNK 16 0 Q2M2I8;Q2M2I8-2 Q2M2I8 AAK1 AP2-associated protein kinase 1 1 S(0.992)T(0.008)QLLQAAAAEASLNK;S(0.995)T(0.005)QLLQAAAAEASLNK 209.43 2.4288999999999998e-63 0.0 19895.2 20749.9 21053.9 16410.0 15412.2 18565.699999999997 18633.9 17109.0 15442.699999999999 10990.8 True False 19611.490799667165 20701.85488142005 19322.92961240423 17616.846142155246 14505.684697551034 17771.688289760506 19598.672165627064 17903.946599475246 13703.380507159787 12890.545135679555 1.521385681772666 1.6059720255057084 1.499000190373685 1.366648652693037 1.1252964513813273 1.3786607240193827 1.520391260364946 1.3889208261580164 1.0630567103970179 1.0 13.654025655499723 -1.522893446990914 0.04020561395845241 1.0466521940207634e-07 3.592398527297259 0.5745603360082103 0.13109829385124502 634.3557994493312 1.9491168211438479 47.62772962116528 155.19305412035047 0.029998984459000677 1.522893446990914 3.5923984226320393 S(ph)TQSEDFSR ddPTM_PC-9_AZD4547_30min_R2 1 STQSEDFSR 9 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 S(0.953)T(0.038)QS(0.008)EDFS(0.001)R 72.73100000000001 0.031497000000000004 5103700.0 10473.0 9364.4 11120.0 13952.0 12445.0 9312.9 8797.5 17448.0 8935.5 11761.0 True False 13803.196148067347 12391.259169177178 10972.541534321077 10735.581956251224 10717.226566336767 8730.562890789042 9580.460456984247 14751.812515153031 9407.812287815203 11349.250969769797 1.2162208928883458 1.091812948905871 0.9668075508725523 0.945928677130045 0.9443113554263176 0.7692633561495846 0.844149140987634 1.299804943466877 0.8289368446317851 1.0 13.470309464919616 -4.975112795735254 1.8200588755524516 0.9474362626677649 1.2508562112587422 0.28891879661611175 0.13547897130501815 0.7795339262527388 3.591600599008187 0.03867060368672744 0.35935682578194006 1.0589786496389517e-05 4.975112795735254 0.3034199485909773 S(ph)TSADSASSSDTSR ddPTM_PC-9_Lapatinib_30min_R1 1 STSADSASSSDTSR 14 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.573)T(0.38)S(0.047)ADSASSSDTSR 128.35 0.00052955 0.0 3488.5 3087.4 4923.7 4398.6 4895.3 3802.0 3851.8 3243.4 4371.8 4457.6 True False 3438.7533502874494 3080.2513149892916 4518.892392031633 4722.087717299456 4607.368078530102 3639.39732289488 4051.2273569978543 3394.10020461383 3879.4018469050866 5228.090220621353 0.6577456021558016 0.5891733281188876 0.8643485864508603 0.90321465736646 0.8812717233449964 0.6961236645343012 0.774896221380887 0.6492045969723997 0.7420303941204793 1.0 12.352068322451883 -5.255773309311019 24.954557729417495 0.8013564435707202 0.6234594504624141 0.35983945413956564 0.10049067330943252 534.5208276080482 2354124.588593451 0.02697729695105903 0.06731911597841941 5.549152890623405e-06 5.255773309311019 -0.1778969931083061 S(ph)TSATDTHHVEMAR ddPTM_PC-9_AZD4547_30min_R2 2 STSATDTHHVEMAR 14 0 H3BQP2;H3BNP3;H3BTL2;H3BS02;O14874-2;O14874-3;O14874 H3BQP2 BCKDK [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial 1 S(0.672)T(0.158)S(0.158)AT(0.003)DT(0.009)HHVEMAR;S(0.771)T(0.211)S(0.017)AT(0.001)DTHHVEMAR 99.238 0.0015637000000000001 52648000.0 15275.7 19013.8 31817.0 54278.0 40298.0 35592.0 28309.0 44338.0 30518.0 39268.0 True False 20133.054845701572 25159.63901487561 31395.0857911415 41765.04568674053 34703.31829411322 33366.426613510666 30828.446158200273 37486.580885881194 32131.1191762682 37893.23927224896 0.531309944263487 0.6639611576649036 0.8285141728206284 1.1021767072134971 0.9158182029459837 0.8805377226735668 0.8135605915532649 0.9892683129186693 0.8479380436551742 1.0 15.209652852261158 -5.217685657297051 2.4597501757504845 0.9282144452440867 0.5528248210466309 0.7337128485714108 0.08129510253138748 0.15923540674876055 1.8074872833038296 0.022547522457074348 0.08242945587775076 6.0577917958015285e-06 5.217685657297051 -0.3753896241974558 S(ph)TSATDTHHVEMAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSATDTHHVEMAR 14 0 H3BQP2;H3BNP3;H3BTL2;H3BS02;O14874-2;O14874-3;O14874 H3BQP2 BCKDK [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial 1 S(0.727)T(0.164)S(0.095)AT(0.002)DT(0.012)HHVEMAR 90.49799999999999 0.0034031999999999995 34246000.0 10999.0 11020.0 19596.0 19128.0 22358.0 16651.0 19110.0 19429.0 15620.0 15775.0 True False 12860.913459847658 12113.992771357194 20063.24295824385 18056.320173812717 17977.11039824592 15777.792247589772 17299.762455581218 18919.009336727126 15848.412949863234 18634.8826251687 0.6901526410731138 0.6500707847226126 1.0766498164654912 0.9689527182438723 0.9647020998117597 0.8466805273181557 0.9283537118830983 1.0152470352120533 0.8504702320184193 1.0 14.18571811159607 -5.248006078125671 24.923947701611613 0.9527537322885381 0.6701116590547268 0.7443193987026848 0.06708586155433115 365.88090466111015 678847.1398583432 0.017144121558908012 0.04478994843798708 5.649290683478087e-06 5.248006078125671 -0.2826420732338113 S(ph)TSATDTHHVEMAR ddPTM_PC-9_Lapatinib_30min_R1 1 STSATDTHHVEMAR 14 0 H3BQP2;H3BNP3;H3BTL2;H3BS02;O14874-2;O14874-3;O14874 H3BQP2 BCKDK [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial 1 S(0.777)T(0.18)S(0.043)ATDTHHVEMAR 100.68 0.001637 3282400.0 23761.0 11041.0 13880.0 10876.0 10810.0 11046.0 9659.7 9835.3 15818.0 8213.8 True False 23422.163782766263 11015.435242857024 12738.839978349428 11675.857321272422 10174.177053277717 10573.588329483646 10159.832000724902 10292.283943527898 14036.410269075584 9633.544385799465 2.4313132160674127 1.1434457352056804 1.3223419613997307 1.212000158371977 1.0561198086423085 1.0975802784559618 1.0546307354644282 1.0683797708660026 1.4570348884016415 1.0 13.2338509785796 -4.761051111504565 24.999999705091668 1.157676565907415 2.431314645818539 0.8918544249970917 0.13314026603436208 2.7631632158305908 177693.03298437002 0.03301766325965255 0.18823115763356 1.7335999608155665e-05 4.761051111504565 1.273638079911124 S(ph)TSDLDKDDASYLR ddPTM_PC-9_Lapatinib_30min_R1 1 STSDLDKDDASYLR 14 1 Q8TEP8;H0Y966 Q8TEP8 CEP192 Centrosomal protein of 192 kDa 1 S(0.929)T(0.059)S(0.012)DLDKDDASYLR 135.61 0.00020504 6812500.0 11341.0 12202.0 12815.0 9488.1 13659.0 11605.0 11798.0 11856.0 14549.0 11762.0 True False 11179.275260315315 12173.747018688642 11761.400167330534 10185.886525373748 12855.604474627218 11108.681202576303 12408.842711942641 12406.873042455933 12910.338412237996 13795.04602812015 0.8103833243852332 0.8824723740590199 0.8525814370866045 0.7383727828533949 0.9319000783630622 0.80526597591136 0.8995144116698242 0.899371630740881 0.9358677300475297 1.0 13.751862649899925 -8.190291588781177 0.6951047016424248 0.9995615990315798 0.834170382189681 0.541025429927368 0.04886420656997783 0.512955737831009 0.5491928867092348 0.045650906649859053 0.01968409380134982 6.452208771266739e-09 8.190291588781177 -0.16539121684189884 S(ph)TSEGAWPQLPSGLSMMR ddPTM_PC-9_Lapatinib_30min_R1 1 STSEGAWPQLPSGLSMMR 18 0 G3V1A6;P57764 G3V1A6 GSDMD Gasdermin-D 1 S(0.364)T(0.364)S(0.273)EGAWPQLPSGLSMMR 93.34200000000001 0.0010458 10259000.0 33330.0 28318.0 37188.0 21938.0 21543.0 25471.0 22982.0 19251.0 27902.0 22764.0 True False 32854.708088026564 28252.431410852732 34130.546189831286 23551.393703022648 20275.88309516759 24381.664705801035 24171.89550821037 20145.471739230707 24759.382938914343 26698.72706887666 1.2305720794579034 1.0581939482720606 1.278358556263084 0.8821167257249903 0.7594325767989019 0.9132145005603403 0.9053576017258188 0.7545480234791704 0.9273619253472554 1.0 14.704483338870626 -5.776191337655477 23.863781983210455 0.8649434769734555 1.1759567087540566 0.7241815504456095 0.08777892716386844 63.39232123614476 102547.7058146148 0.02341194299887361 0.0349167434308254 1.6742051069098162e-06 5.776191337655477 0.31101323178060103 S(ph)TSFGVPNANSIK ddPTM_PC-9_AZD4547_30min_R2 2 STSFGVPNANSIK 13 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6;P53814-2;H7BZZ8;B5MCI0;A0A096LNK9 A0A087WVP4 SMTN Smoothelin 1 S(0.37)T(0.37)S(0.26)FGVPNANSIK;S(0.333)T(0.333)S(0.333)FGVPNANSIK 148.85 0.0001182 20433500.0 83472.0 78461.0 100840.0 141592.0 111729.0 106468.0 94368.0 116285.0 99753.0 95295.0 True False 110014.3596745418 103821.98386151924 99502.79571231455 108950.15197459314 96217.35693292387 99810.53912922174 102766.56918496056 98315.82521346676 105025.7399302143 91958.75105554055 1.1963446481357296 1.1290060235682586 1.0820372674724301 1.1847719844388738 1.0463099577636852 1.0853838050599331 1.1175289790842462 1.0691296269790214 1.1420961977482889 1.0 16.488699251671072 -14.522878741210398 0.016829984977019125 2.7263473100045606e-07 1.928573364038896 0.4319243047225736 0.043613852398503496 4599.856073729674 5.846757302063009 431.20329807436315 259.05897856936144 3.0000000281141442e-15 14.522878741210398 1.928573091404165 S(ph)TSFRGGMGSGGLATGIAGGLAGMGGIQNEK ddPTM_PC-9_AZD4547_30min_R2 8 STSFRGGMGSGGLATGIAGGLAGMGGIQNEK 31 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.289)T(0.289)S(0.289)FRGGMGS(0.066)GGLAT(0.066)GIAGGLAGMGGIQNEK;S(0.25)T(0.25)S(0.231)FRGGMGS(0.213)GGLAT(0.056)GIAGGLAGMGGIQNEK;S(0.323)T(0.323)S(0.323)FRGGMGS(0.023)GGLAT(0.009)GIAGGLAGMGGIQNEK;S(0.332)T(0.127)S(0.334)FRGGMGS(0.186)GGLAT(0.021)GIAGGLAGMGGIQNEK;S(0.314)T(0.314)S(0.314)FRGGMGS(0.048)GGLAT(0.01)GIAGGLAGMGGIQNEK;S(0.318)T(0.318)S(0.318)FRGGMGS(0.033)GGLAT(0.012)GIAGGLAGMGGIQNEK;S(0.235)T(0.235)S(0.235)FRGGMGS(0.235)GGLAT(0.061)GIAGGLAGMGGIQNEK;S(0.337)T(0.337)S(0.302)FRGGMGS(0.018)GGLAT(0.006)GIAGGLAGMGGIQNEK 70.632 2.222e-05 15936700.0 83980.74 88674.68 108477.09999999999 174107.29999999996 132031.80000000002 109385.01999999999 102782.23 117657.18999999999 89983.50000000003 94388.00000000001 True False 110684.86841209258 117337.03618212085 107038.62277632205 133969.55191597034 113701.46360476206 102545.15740749022 111929.64935443708 99475.97477875612 94739.84410504378 91083.50484947131 1.2152021224371565 1.2882358488075014 1.1751702237767299 1.4708431799739639 1.24832112897577 1.125836753613741 1.228868493141728 1.092140392963079 1.0401427158695211 1.0 16.47490218630358 -7.731398382729632 0.8603138761033354 0.998745989205234 1.2790406481737426 0.5892194715513084 0.08270565585038592 0.4343512697508815 0.5925733327694432 0.07575302098317013 0.033330623202364136 1.856101053630173e-08 7.731398382729632 0.2802946589685086 S(ph)TSFRGGMGSGGLATGIAGGLAGMGGIQNEK ddPTM_PC-9_Lapatinib_30min_R1 3 STSFRGGMGSGGLATGIAGGLAGMGGIQNEK 31 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.333)T(0.333)S(0.295)FRGGMGS(0.029)GGLAT(0.01)GIAGGLAGMGGIQNEK;S(0.713)T(0.143)S(0.132)FRGGMGS(0.006)GGLAT(0.007)GIAGGLAGMGGIQNEK;S(0.412)T(0.412)S(0.16)FRGGMGS(0.01)GGLAT(0.004)GIAGGLAGMGGIQNEK 72.469 1.0593e-05 31369700.0 115543.6 56700.3 97970.4 71352.4 89421.4 73120.3 62226.6 65445.8 93542.8 73137.6 True False 113895.92707589868 56569.01393900602 89915.65188868053 76599.89352062884 84161.80906123652 69993.1152207445 65448.38887090783 68486.65078963924 83007.02481464687 85779.33671027393 1.3277781275062854 0.6594713378359647 1.0482204145781322 0.8929877107741071 0.9811431550875623 0.8159670837412911 0.7629854855600553 0.7984049937452651 0.9676808891051378 1.0 16.388342539909743 -6.756662528405795 24.97515390063993 0.8497816111557179 0.9627489949993643 0.08985290590422568 0.1689722797929165 290.7099569198128 1519939.4254356278 0.05341253937186696 0.05175873661307813 1.7512069477827362e-07 6.756662528405795 0.11296738384364635 S(ph)TSFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQSLNDR ddPTM_PC-9_AZD4547_30min_R2 1 STSFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQSLNDR 40 2 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.383)T(0.383)S(0.213)FRGGMGS(0.02)GGLAT(0.001)GIAGGLAGMGGIQNEKETMQSLNDR 44.36600000000001 0.012790000000000001 9327000.0 8903.3 1890.7 10172.0 40386.0 22174.0 11433.0 8972.6 11383.0 6751.9 9682.1 True False 11734.364199855638 2501.8318003463432 10037.112633733275 31075.63165748008 19095.522851100966 10718.092702637314 9771.144017770595 9624.018905317917 7108.7916497229535 9343.132626001881 1.2559346709045929 0.2677722665933009 1.0742770155911148 3.3260398734998993 2.043803038603802 1.1471626414473586 1.0458102660961444 1.0300633942125932 0.7608574055707215 1.0 13.189690631841383 -6.96757678273249 13.048427772694641 0.9809131742853543 1.5882453011054087 0.1450871156334672 0.7349233119943199 3.012588809163858 1208.177528187572 0.2951563147695286 0.2601035517738015 1.0775147335677685e-07 6.96757678273249 0.6073321268200544 S(ph)TSLEPVER ddPTM_PC-9_AZD4547_30min_R2 2 STSLEPVER 9 0 Q8N4X5-2;Q8N4X5;Q8N4X5-4 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 S(0.976)T(0.017)S(0.007)LEPVER;S(0.964)T(0.025)S(0.011)LEPVER 100.69 0.0037398 33233000.0 42529.0 45803.0 68688.0 100643.0 73431.0 61387.0 66452.0 72540.0 60915.0 71389.0 True False 56052.33734184629 60607.924023516985 67777.15224005813 77441.31126884966 63236.373161323754 57548.46118576026 72366.09926541838 61330.60980337005 64134.842539562786 68889.69283912062 0.8136534658783623 0.8797821782288361 0.9838504055801116 1.1241349478752911 0.9179366397960408 0.8353711391942805 1.0504633753327406 0.8902726558325142 0.9309787850170573 1.0 16.07200052500079 -5.040210645265124 3.438567515069894 0.9644399170703516 0.8205623240479741 0.29262043037124863 0.07760495707441996 0.31547421415308546 7.386520077984622 0.021035489724758306 0.0837926928963587 9.115685952313017e-06 5.040210645265124 -0.14387759302237746 S(ph)TSLEPVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSLEPVER 9 0 Q8N4X5-2;Q8N4X5;Q8N4X5-4 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 S(0.94)T(0.059)S(0.001)LEPVER 77.288 0.023277000000000003 15152000.0 20746.0 36756.0 27771.0 34835.0 32505.0 19937.0 25541.0 26886.0 22115.0 19541.0 True False 24257.888047822493 40404.89276805854 28433.165962104005 32883.307886593764 26135.87858909489 18891.468622917375 23121.571579173178 26180.27098807174 22438.390037530447 23083.628613529123 1.050869794084503 1.75037007588909 1.2317459459315492 1.4245294116073732 1.1322257443431951 0.8183925040210204 1.0016437175575514 1.134148856160669 0.9720477838730907 1.0 14.494582404714285 -6.421889873310469 3.976005213569536 0.9924998293678159 1.3810138767219688 0.49483290861112617 0.17966707520101663 0.18978258007907026 5.315334812443835 0.05541360334803305 0.062474571314886644 3.785385608699438e-07 6.421889873310469 0.38851404735415296 S(ph)TSLEPVER ddPTM_PC-9_Lapatinib_30min_R1 4 STSLEPVER 9 0 Q8N4X5-2;Q8N4X5;Q8N4X5-4 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 S(0.969)T(0.029)S(0.002)LEPVER;S(0.99)T(0.01)SLEPVER;S(0.986)T(0.013)S(0.002)LEPVER;S(0.982)T(0.014)S(0.004)LEPVER 121.36 0.0016214000000000003 73247000.0 111689.0 188360.0 201637.0 172393.0 199000.0 212891.0 187499.0 179323.0 233516.0 243279.0 True False 110096.29437874565 187923.8639928036 185059.18420132855 185071.35630618993 187295.21124905304 203786.14820315977 197206.78078034706 187655.0012307964 207214.96904750625 285329.4510011085 0.38585674907536244 0.6586206342648924 0.6485807320345968 0.6486233918610488 0.6564173820540011 0.7142135082381246 0.6911546638050374 0.6576783454087513 0.7262305672284114 1.0 18.122269140460467 -14.522878745280295 0.08588828569595042 2.102938042247201 0.34606563072995994 0.7530701712909563 0.0695368438955682 120.18231733256768 0.7202833518526871 24.78610609262503 1.9424615739934705 3.0000000000002957e-15 14.522878745280295 -1.756872411517241 S(ph)TSPIIGSPPVR ddPTM_PC-9_AZD4547_30min_R2 1 STSPIIGSPPVR 12 0 Q86TB9-4;Q86TB9;Q86TB9-2 Q86TB9-4 PATL1 Protein PAT1 homolog 1 1 S(0.873)T(0.026)S(0.101)PIIGSPPVR 147.33 0.00013447 55646000.0 137210.0 154600.0 154630.0 176690.0 157840.0 143990.0 128840.0 190750.0 133530.0 119260.0 True False 180839.92585470426 204571.4266322235 152579.50516655296 135956.85033328753 135926.6405167209 134986.2825376318 140306.51040384796 161273.97049893634 140588.1231931022 115084.74369991897 1.5713631541487423 1.7775720747629171 1.3258013204982304 1.1813629327601591 1.1811004321402212 1.1729294274626503 1.219158212401239 1.401349695138174 1.2216052160630668 1.0 16.8123370685733 -5.398042344687228 4.243624806258446 1.2149853720088808 1.6713237230642095 0.7638674557495293 0.10415537777782342 0.10170323617118272 2.9876220771651094 0.027431321690354404 0.060413796649106635 3.999057561509013e-06 5.398042344687228 0.4563383510553287 S(ph)TSPIIGSPPVR ddPTM_PC-9_Lapatinib_30min_R1 2 STSPIIGSPPVR 12 0 Q86TB9-4;Q86TB9;Q86TB9-2 Q86TB9-4 PATL1 Protein PAT1 homolog 1 1 S(0.716)T(0.052)S(0.232)PIIGSPPVR;S(0.476)T(0.049)S(0.476)PIIGSPPVR 189.24 8.242e-05 111872000.0 243960.0 302640.0 334320.0 241660.0 265780.0 218644.0 189441.0 202736.0 182242.0 126442.0 True False 240481.085663215 301939.2556741456 306833.50011252036 259432.48255412743 250147.34294358484 209293.10580405788 199249.32803806782 212155.85468415509 161715.9868666627 148297.33122662568 1.621614385600207 2.0360397127627787 2.069042629254212 1.7494076286353848 1.6867959852987073 1.4113072977976886 1.343579998304744 1.4306114137680725 1.0904848086546535 1.0 17.178133109580962 -7.092521860623649 0.603970034746385 1.0564595705093611 1.9553287796738632 0.8171298102464097 0.14556023917200525 0.3425980089891446 0.2610394454813044 0.13171887885987651 0.11063055353764102 8.08124250390004e-08 7.092521860623649 0.8988692091645021 S(ph)TSPSAAGGQQK ddPTM_PC-9_AZD4547_30min_R2 2 STSPSAAGGQQK 12 0 Q2TB10 Q2TB10 ZNF800 Zinc finger protein 800 1 S(0.469)T(0.469)S(0.061)PSAAGGQQK;S(0.327)T(0.327)S(0.299)PS(0.046)AAGGQQK 156.83 1.0862000000000001e-11 6993900.0 62033.0 71430.0 74640.0 79938.0 80292.0 84461.0 77871.0 90201.0 86565.0 83308.0 True False 81758.20363344422 94518.35061021813 73650.22483109037 61509.52912978857 69144.84174080454 79179.64031815353 84801.36814388397 76262.50806277627 91140.64917404985 80391.4122769817 1.0170017084878837 1.1757269580557097 0.9161454282869773 0.7651256196104974 0.8601023390728841 0.9849265994400854 1.0548560566607306 0.9486399840821349 1.1337112583621813 1.0 16.294753774894787 -7.001651990747273 24.849384381604864 1.028574619742984 0.9452166573359985 0.12526093606151878 0.10851771251110014 153.07186564705492 2302557.479392673 0.04332939202978605 0.037669433222543555 9.962033762017561e-08 7.001651990747273 -0.08335796240698545 S(ph)TSPSAAGGQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STSPSAAGGQQK 12 0 Q2TB10 Q2TB10 ZNF800 Zinc finger protein 800 1 S(0.969)T(0.016)S(0.016)PSAAGGQQK;S(0.497)T(0.497)S(0.005)PSAAGGQQK 153.05 8.307e-08 5211700.0 65011.0 90244.0 80188.0 69241.0 109889.0 72548.0 71029.0 62786.0 63921.0 57361.0 True False 76016.07827422097 99202.82791818157 82099.98603468364 65361.651252350865 88357.039294787 68743.45516654504 64300.618914572406 61137.93402726594 64855.72369834879 67760.09523057392 1.1218413730906607 1.4640302316668001 1.2116273708783019 0.9646038871394493 1.3039686410434612 1.0145123753534429 0.9489452264754114 0.9022704855892822 0.957137434321157 1.0 16.04814828179601 -6.490231058522736 0.7153179856894303 0.9287357532688884 1.2875435690980128 0.4711001345451581 0.12675741923482076 0.6204268547667373 0.7058631996639892 0.08461215396861028 0.11538398999867694 3.2342154056800684e-07 6.490231058522736 0.35880781582912447 S(ph)TSPSAAGGQQK ddPTM_PC-9_Lapatinib_30min_R1 1 STSPSAAGGQQK 12 0 Q2TB10 Q2TB10 ZNF800 Zinc finger protein 800 1 S(0.832)T(0.084)S(0.084)PSAAGGQQK 153.49 6.6544e-08 0.0 36490.0 49878.0 47740.0 40935.0 52376.0 44830.0 50798.0 51684.0 47216.0 38794.0 True False 35969.64590855356 49762.51055549522 43815.00148172919 43945.496455156914 49295.34665517796 42912.72540383416 53428.07188347707 54085.42732171831 41898.03687347784 45499.4912102443 0.7905505084077715 1.0936937805645417 0.9629778337359552 0.9658458872010969 1.083426327283392 0.9431473685176568 1.1742564688601975 1.1887040026843392 0.9208462723214895 1.0 15.473562792277015 -4.754045223481613 24.996572403046454 1.0411578688167562 0.7905500661628021 0.4004776356922286 0.09032756131397995 275.7545412644858 932133.5399006377 0.022769904009097064 0.2313584698022798 1.7617925797868242e-05 4.754045223481613 -0.2506078026539541 S(ph)TSPTFNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSPTFNK 8 0 Q9BX63 Q9BX63 BRIP1 Fanconi anemia group J protein 1 S(0.984)T(0.008)S(0.008)PT(0.001)FNK 111.06 0.003752 8121400.0 82682.0 101750.0 90985.0 100210.0 104610.0 88354.0 102440.0 96180.0 92314.0 73001.0 True False 96678.42955606185 111851.06755767636 93154.42746253383 94595.5585852033 84112.42144916848 83720.56070167242 92736.14159862565 93655.37691113353 93663.91760907031 86235.50342440182 1.1210977580807515 1.2970419736197212 1.0802328943808797 1.0969444698392734 0.9753804188422865 0.9708363420765078 1.0753823879502553 1.0860419802991736 1.0861410195300896 1.0 16.395994333191304 -5.43507292465989 5.15719269962075 1.0438128944523288 1.2085715363549647 0.5538852482521321 0.05915094921151425 0.15877807510192662 6.91131400800139 0.016010699970242865 0.0339864577137155 3.672206333819372e-06 5.43507292465989 0.1647586419026359 S(ph)TSPTFNK ddPTM_PC-9_Lapatinib_30min_R1 2 STSPTFNK 8 0 Q9BX63 Q9BX63 BRIP1 Fanconi anemia group J protein 1 S(0.333)T(0.333)S(0.333)PTFNK;S(0.485)T(0.03)S(0.485)PTFNK 160.82 2.7806999999999997e-05 71652000.0 579050.0 469290.0 528570.0 514440.0 511350.0 478320.0 432980.0 434080.0 530050.0 362750.0 True False 570792.6408152352 468203.38783809124 485113.0149392051 552273.6337215332 481273.398352781 457863.36861837906 455397.5858125887 454248.94148694916 470350.18732605287 425450.8541660089 1.3416182744165197 1.100487596283919 1.1402327911414094 1.2980903159875634 1.1312079730012492 1.076183921444715 1.0703882278137224 1.0676883993508293 1.1055335362954155 1.0 18.698632963466828 -6.537153935731157 4.354564628948706 1.0701653437953975 1.2073092647838475 0.5217472226123152 0.06975696955928172 0.1851304436846572 8.535594083738529 0.02295348214533706 0.0239575476203336 2.902993505688279e-07 6.537153935731157 0.13714392098844996 S(ph)TSPVTDPSIPIR ddPTM_PC-9_Lapatinib_30min_R1 2 STSPVTDPSIPIR 13 0 A0A087WU18;Q99607 A0A087WU18 ELF4 ETS-related transcription factor Elf-4 1 S(0.372)T(0.372)S(0.254)PVT(0.001)DPSIPIR;S(0.739)T(0.129)S(0.129)PVT(0.004)DPSIPIR 164.92 0.00032099 55021700.0 87505.0 75248.0 83597.0 72145.0 82459.0 82206.0 79470.0 81895.0 85962.0 66218.0 True False 86257.1626535482 75073.76787922326 76723.9773537518 77450.7839686648 77608.92374063162 78690.2410115457 83584.56775030354 85700.14067239598 76280.05434000978 77663.69307006117 1.1106497675269547 0.9666520469416576 0.98790019275208 0.9972585761379605 0.9992947885007202 1.0132178615374172 1.076237356816152 1.1034775360873588 0.982184226948837 1.0 16.244952691575428 -7.11459550623836 7.230780538309683 1.0489653677938233 1.0074955444684095 0.05903050812659971 0.04841525702277116 0.5334956353188751 30.293651033105352 0.018127940479565362 0.014036323362979051 7.680765284430985e-08 7.11459550623836 -0.041469823325413824 S(ph)TSPVTDPSIPIRK ddPTM_PC-9_AZD4547_30min_R2 1 STSPVTDPSIPIRK 14 1 A0A087WU18;Q99607 A0A087WU18 ELF4 ETS-related transcription factor Elf-4 1 S(0.331)T(0.331)S(0.331)PVT(0.008)DPSIPIRK 72.315 0.010576 11188000.0 51334.0 41103.0 66740.0 83557.0 80610.0 63184.0 55799.0 72170.0 59111.0 62314.0 True False 67657.14418646893 54388.74093702635 65854.9839928587 64294.22459278121 69418.69292988387 59233.094491685115 60765.00290301385 61017.784801615904 62235.486782501735 60132.405826905415 1.1251361600469454 0.9044830352137825 1.0951662932367292 1.0692109139597015 1.1544306597296234 0.9850444810438981 1.0105200692939078 1.0147238242431063 1.0349741695293244 1.0 15.875855059771638 S(ph)TSQELAK ddPTM_PC-9_Lapatinib_30min_R1 1 STSQELAK 8 0 E7EV90;Q5BKX6-2;Q5BKX6;Q5BKX6-3 E7EV90 SLC45A4 Solute carrier family 45 member 4 1 S(0.961)T(0.023)S(0.016)QELAK 84.81700000000001 0.013691 3196900.0 86912.0 106890.0 55695.0 37762.0 45057.0 41762.0 25453.0 28809.0 53997.0 19645.0 True False 85672.61894229136 106642.50277230208 51115.97208891724 40539.143450339216 42406.83584547029 39975.93661197685 26770.83179751451 30147.57131242518 47915.28924638223 23040.612074682896 3.718330861376236 4.628457891076653 2.2185162409415176 1.7594646929924125 1.840525577533032 1.7350206011194707 1.1618975967626481 1.3084535781734477 2.0796014051654343 1.0 14.491891422084041 -5.399031034019142 3.597330518583775 1.587283993854869 4.1720028719419755 0.8785092238508527 0.3824489277553707 0.07163606198009878 1.65481940990003 0.10273408055406258 0.23530249013910287 3.989963896719351e-06 5.399031034019142 2.5847188780871067 S(ph)TSSSSDTMSTFKPMVAPR ddPTM_PC-9_Lapatinib_30min_R1 1 STSSSSDTMSTFKPMVAPR 19 1 G5EA48;Q7Z6B7-2;Q7Z6B7 G5EA48 SRGAP1 SLIT-ROBO Rho GTPase-activating protein 1 1 S(0.324)T(0.324)S(0.324)S(0.012)S(0.012)S(0.001)DT(0.004)MS(0.001)TFKPMVAPR 55.208999999999996 0.014833 4039000.0 16500.0 13441.0 19162.0 12696.0 13154.0 15156.0 10412.0 12546.0 15560.0 10910.0 True False 16264.706974270592 13409.878190312584 17586.57432745904 13629.706192614445 12380.307581759025 14507.813210361606 10951.082413692733 13128.93296142477 13807.468945936027 12795.778963338795 1.2710994008938907 1.0479923284649764 1.3744043545802376 1.06517205647776 0.9675305909261064 1.133796797516428 0.8558355411631207 1.0260362420326654 1.0790643528225852 1.0 13.643380355948963 -5.982181307326781 24.4931855251122 1.01068916402905 1.2140048729266328 0.48586008515153845 0.10127719269454157 164.1314156041574 225609.1410161687 0.02721956095497039 0.04036293398654478 1.041882378171329e-06 5.982181307326781 0.20331570889758277 S(ph)TSSTSSGSNSNALVPVSWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSSTSSGSNSNALVPVSWK 20 0 H0Y9X0;A0A286YEZ9;A0A2C9F2R7;O94915 H0Y9X0 FRYL Protein furry homolog-like 1 S(0.346)T(0.346)S(0.174)S(0.047)T(0.012)S(0.012)S(0.016)GS(0.023)NS(0.023)NALVPVSWK 73.918 0.034787 0.0 4978.5 7039.1 5625.0 7147.7 6533.4 7428.8 6780.5 6855.9 6551.4 4561.3 True False 5821.261720142886 7737.8953282087505 5759.12133293129 6747.237542156059 5253.227170404324 7039.220650345015 6138.201953431105 6675.9398894265005 6647.201830968884 5388.227582769065 1.0803667125640006 1.4360743323005982 1.0688340914456362 1.2522183665242634 0.9749453024596704 1.3064074488716173 1.1391875823991497 1.2389862504648825 1.2336527603670406 1.0 12.395595071913366 -11.906952585766785 1.8521414586064704 4.046225141313999e-05 1.1943727441481673 0.17399953911780375 0.12561927489240005 2006477.3493827581 203588.22820459885 8378070.808708106 0.031458668587793476 1.2389318399105452e-12 11.906952585766785 1.194332281896754 S(ph)TSSTSSGSNSNALVPVSWK ddPTM_PC-9_Lapatinib_30min_R1 1 STSSTSSGSNSNALVPVSWK 20 0 H0Y9X0;A0A286YEZ9;A0A2C9F2R7;O94915 H0Y9X0 FRYL Protein furry homolog-like 1 S(0.72)T(0.133)S(0.133)S(0.007)T(0.007)SSGSNSNALVPVSWK 188.09 1.024e-11 7543400.0 110140.0 104160.0 111650.0 82309.0 103660.0 93398.0 109920.0 96334.0 101050.0 69792.0 True False 108569.38340279744 103918.82391957122 102470.56798146333 88362.27843477511 97562.92260340131 89403.58526137186 115611.11975730926 100810.02932455712 89668.68489632611 81855.45420800567 1.326354907602224 1.269540617971523 1.251847772062591 1.0794916391305427 1.191892752259133 1.092212927365663 1.4123813846726196 1.2315615410108818 1.0954515586519864 1.0 16.320790929378745 -14.522878745243935 0.20006527418788167 0.010098102374934716 1.2518037240093296 0.328557800322552 0.09917481959505713 187.50419912773202 1.8500155301699288 74.09526260460468 0.2505196136094955 3.0000000002514635e-15 14.522878745243935 1.241705621634395 S(ph)TSTLYSQFQTAESENR ddPTM_PC-9_Lapatinib_30min_R1 1 STSTLYSQFQTAESENR 17 0 O95248;O95248-5;O95248-4;H0Y5W8 O95248 SBF1 Myotubularin-related protein 5 1 S(0.567)T(0.415)S(0.015)T(0.003)LYSQFQTAESENR 114.28 0.0018690000000000002 0.0 8284.3 6766.8 8275.6 5437.4 7640.2 7407.0 9721.1 5078.9 7853.1 6780.2 True False 8166.164362845446 6751.131890350956 7595.212112739799 5837.284534634668 7190.818457211134 7090.219876560331 10224.41099229239 5314.8842354360195 6968.601181190887 7952.148535951394 1.0269129564075035 0.8489695407259206 0.955114467291714 0.7340512451753765 0.9042610842468155 0.8916105936031863 1.2857419533938754 0.6683582696434314 0.8763167777470551 1.0 12.95712898950986 -7.045203898446824 24.998821915439752 0.9526400054564007 0.8870960049826466 0.03688515347863919 0.15785673065405761 1875.6152447405225 1037253.6397828233 0.06076233295166131 0.047068257404249164 9.011479551437833e-08 7.045203898446824 -0.06554400047375408 S(ph)TSTPNVHMVSTTLPVDSR ddPTM_PC-9_AZD4547_30min_R2 1 STSTPNVHMVSTTLPVDSR 19 0 P04049;P04049-2;H7C155 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 S(0.535)T(0.025)S(0.111)T(0.09)PNVHMVS(0.239)T(0.001)TLPVDSR 97.273 0.00054067 46651000.0 18587.0 15169.0 28027.0 51463.0 40099.0 30950.0 26868.0 34948.0 29254.0 35280.0 True False 24497.27936638288 20072.082604037485 27655.34366748353 39599.000445424084 34531.94600912319 29014.69160733184 29259.199949787195 29547.589625147182 30800.306716775318 34044.85793839626 0.7195588658560538 0.5895775109520993 0.812320724543058 1.1631418911213547 1.0143072434494604 0.8522488670633773 0.8594308133913012 0.8679016866104472 0.9046977600114556 1.0 15.055149292706648 -5.521119940594847 24.99997955568955 0.9444052410754671 0.6661633806058423 0.6174359748466608 0.09363876923289448 44.595794392566525 633892.0843065252 0.027672401072206157 0.048861453451242785 3.0121740268837088e-06 5.521119940594847 -0.27824186046962474 S(ph)TSTPNVHMVSTTLPVDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSTPNVHMVSTTLPVDSR 19 0 P04049;P04049-2;H7C155 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 S(0.439)T(0.439)S(0.099)T(0.023)PNVHMVSTTLPVDSR 75.539 0.0027778000000000004 11599000.0 9512.8 9029.8 14335.0 11788.0 15661.0 14808.0 14628.0 12109.0 9085.3 7723.4 True False 11123.129153635671 9926.218868130782 14676.80076579024 11127.556577211644 12592.339473429174 14031.442412005836 13242.32994245118 11791.151580546022 9218.155324801051 9123.591281599238 1.2191612721702219 1.0879727688098337 1.60866486811952 1.2196465441907804 1.3801954827619056 1.5379297448697549 1.451438313458731 1.2923805129594974 1.0103647829328495 1.0 13.155386102945478 -10.432582479317965 9.466269339985251 1.000000000061256 1.3235732509857625 0.21097490291371912 0.17973987544095257 0.0 0.0 0.17747615481500068 0.04304429013710119 3.693324956770745e-11 10.432582479317965 0.3235732509245066 S(ph)TSTPNVHMVSTTLPVDSR ddPTM_PC-9_Lapatinib_30min_R1 2 STSTPNVHMVSTTLPVDSR 19 0 P04049;P04049-2;H7C155 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 S(0.429)T(0.429)S(0.112)T(0.03)PNVHMVSTTLPVDSR;S(0.303)T(0.303)S(0.303)T(0.092)PNVHMVSTTLPVDSR 94.087 0.00054197 15980000.0 47577.0 34806.0 44871.0 33687.0 40757.0 49272.0 41489.0 31016.0 43090.0 30115.0 True False 46898.543255446784 34725.40884547427 41181.87958706894 36164.454356537724 38359.75339134502 47164.751418641914 43637.097412763906 32457.116589474812 38236.75044218402 35320.33762428483 1.3278056329563863 0.9831561978501158 1.165953735355971 1.023898886279969 1.0860528514588832 1.3353425983735032 1.2354665993555172 0.9189356266843445 1.0825703550436614 1.0 15.108211513208348 -7.760859292633326 24.99999972226884 1.0005647443153898 1.1564397601122032 0.29725096879593804 0.1156051229141064 21.355450841955548 920502.1939145087 0.05949662987667625 0.03166188868834161 1.7343658251074862e-08 7.760859292633326 0.1558750157968134 S(ph)TSTPTSPGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSTPTSPGPR 11 0 H3BUF6;H3BRB0;A0A0C4DGL7;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 S(0.598)T(0.058)S(0.343)T(0.001)PTSPGPR 131.42 0.00015975 24691000.0 27248.0 33998.0 51042.0 55936.0 64283.0 53788.0 54806.0 45548.0 50041.0 34727.0 True False 31860.54822746878 37373.096755045546 52259.034857862964 52802.08726695883 51687.207609376645 50967.26259163762 49614.37891892119 44352.41326209519 50772.754956728975 41022.73020121925 0.7766559678302893 0.9110338724830842 1.273904359888503 1.2871422016028928 1.2599650816961088 1.242415176699351 1.2094362972810275 1.0811667835013326 1.2376737166854863 1.0 15.32413589078908 -5.1209737574753085 3.841332308055022 1.2086560319022066 0.8012013664776354 0.7290158184255229 0.08786151001130119 0.1098529021378791 2.7729602686548778 0.02270271661009242 0.07264564226913586 7.568786285194133e-06 5.1209737574753085 -0.4074546654245712 S(ph)TSTPTSPGPR ddPTM_PC-9_Lapatinib_30min_R1 2 STSTPTSPGPR 11 0 H3BUF6;H3BRB0;A0A0C4DGL7;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 S(0.701)T(0.001)S(0.069)T(0.181)PT(0.047)SPGPR;S(0.994)T(0.006)STPTSPGPR 157.97 8.459e-12 22080000.0 82189.0 85258.0 99095.0 90986.0 86962.0 98239.0 64638.0 67474.0 96655.0 68247.0 True False 81016.96978838343 85060.59033923571 90947.7916177618 97677.4139603984 81847.06613387015 94037.54697629414 67984.6393638371 70609.08836594729 85768.69607772795 80043.40301658865 1.012162985769021 1.0626808348166716 1.1362309470889596 1.2203056126955918 1.022533563658053 1.174831946572852 0.8493471891711997 0.8821350130667716 1.071527356975974 1.0 16.28849488375952 -7.256653127492813 24.9960710323004 0.9409303071262204 1.1058176653602865 0.45132716855883914 0.0829173342173883 364.8743172320479 1905550.2532251084 0.03273999372669385 0.024509621585760793 5.53792248410442e-08 7.256653127492813 0.16488735823406608 S(ph)TSVPENPK ddPTM_PC-9_Lapatinib_30min_R1 1 STSVPENPK 9 0 A0A494C0P1;P04150-7;P04150-5;P04150-2;P04150-6;P04150-10;P04150;P04150-3;D6RDA9;Q3MSN4;P04150-9;P04150-8;P04150-13;P04150-12;P04150-11 A0A494C0P1 NR3C1 Glucocorticoid receptor 1 S(0.648)T(0.009)S(0.343)VPENPK 141.91 0.0006911 42285000.0 195910.0 165610.0 152010.0 116170.0 245860.0 188810.0 310840.0 191940.0 245220.0 274110.0 True False 193116.28747450575 165226.54022004775 139512.32457556858 124713.52933175972 231398.99817935802 180735.03643760708 326933.77424819896 200858.23311141986 217600.74131892255 321489.54827138386 0.600692272930402 0.5139406276454517 0.4339560191791987 0.38792405539256725 0.7197714495652084 0.5621801312341279 1.0169343793790129 0.6247737576273128 0.6768516814588197 1.0 18.294412310272627 -6.696961989996594 1.6971263796654878 0.7890838286535597 0.489508870492382 0.4774908514243422 0.14587274335713662 0.33518429016331047 1.995999036152717 0.05959876755440086 0.05709148866516182 2.009268658652687e-07 6.696961989996594 -0.29957495816117774 S(ph)TTELDDYSTNK ddPTM_PC-9_AZD4547_30min_R2 2 STTELDDYSTNK 12 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.998)T(0.002)TELDDYSTNK;S(0.973)T(0.013)T(0.013)ELDDYSTNK 198.37 8.7678e-06 36819000.0 49562.0 60293.0 84314.0 81641.0 73943.0 84315.0 98720.0 103465.0 99638.0 85043.0 True False 65321.68504635868 79781.53315612307 83195.94127021109 62819.92879087627 63677.29079908708 79042.76972123387 107505.88875401925 87476.86163917417 104904.66126499137 82065.67045507453 0.7959684565316253 0.9721669574343894 1.0137727603865163 0.7654836479434599 0.7759309153995901 0.9631648566681058 1.3099982996284851 1.0659373298736639 1.278301397932521 1.0 16.32449122248059 -7.062781032596912 5.977140794444592 1.1672389219313144 0.8727332335280608 0.6091725487613592 0.11299738129350115 0.15400218649210937 11.022503974103874 0.043059715101883105 0.03359463043440158 8.65404137842911e-08 7.062781032596912 -0.29450568840325364 S(ph)TTELDDYSTNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 STTELDDYSTNK 12 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.851)T(0.074)T(0.074)ELDDYSTNK;S(0.995)T(0.001)T(0.004)ELDDYSTNK;S(0.45)T(0.45)T(0.1)ELDDYSTNK 217.46 6.4423e-11 28909500.0 51815.0 63726.0 69293.0 85378.0 100894.0 89961.0 108671.0 81901.0 77859.0 78447.0 True False 60586.25610710125 70052.296129538 70945.207915166 80594.54745921052 81124.54497363922 85243.28679271051 98376.89617009243 79751.1855312824 78997.54058024343 92668.82011388973 0.6537933258742359 0.7559424631007917 0.7655779778783687 0.869705121530198 0.8754243862599888 0.9198702075622279 1.0615965116334436 0.860604305021564 0.8524716348298776 1.0 16.499796382544275 -5.488150255231851 0.8208282363400139 0.9377124043205072 0.6360300962600671 0.7092358021586448 0.06063757659489875 0.645977512629202 0.6451440877511211 0.027079207442573607 0.14819360987668592 3.2497484461322656e-06 5.488150255231851 -0.30168230806044005 S(ph)TTELDDYSTNK ddPTM_PC-9_Lapatinib_30min_R1 2 STTELDDYSTNK 12 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.991)T(0.008)T(0.001)ELDDYSTNK;S(0.982)T(0.009)T(0.009)ELDDYSTNK 213.18 1.1561e-10 34637000.0 52629.0 85106.0 87184.0 80399.0 103328.0 93815.0 95559.0 114784.0 100255.0 94709.0 True False 51878.5008090234 84908.94228589688 80016.06805997217 86311.81066320156 97250.45019066423 89802.75114344628 100506.5774462219 120117.28367959347 88963.22616804726 111079.32445819 0.46704011806040774 0.7643991597901407 0.7203506903761376 0.7770285882112032 0.8755045159395893 0.8084560432958684 0.9048180472510196 1.0813649098559772 0.8008981563579171 1.0 16.761230782815474 -4.127249010405367 0.3564630963418318 0.9695253341404388 7.37406215503301e-14 0.707098457113578 0.08573140703126628 5.717227946848791 0.4051594089092665 0.07529866952330223 2.6062810850537477 7.460208915157921e-05 4.127249010405367 -0.9695253341403651 down S(ph)TTELLPR ddPTM_PC-9_AZD4547_30min_R2 1 STTELLPR 8 0 Q9BZL6-2;Q9BZL6;Q9BZL6-3 Q9BZL6-2 PRKD2 Serine/threonine-protein kinase D2 1 S(0.916)T(0.077)T(0.008)ELLPR 96.14299999999999 0.0062104 2086000.0 4074.9 6159.7 7960.3 7285.0 7593.4 9074.4 8159.5 9027.5 6496.0 6426.0 True False 5370.6334368146345 8150.702565501333 7854.741220832377 5605.5558021280185 6539.187481624874 8506.976333491824 8885.679692954012 7632.507306312699 6839.36529815316 6201.027695922177 0.8660876390451193 1.3144115725948573 1.2666837830764228 0.9039720635039666 1.0545328616940497 1.37186556013708 1.4329366241659063 1.2308455437687964 1.1029406146098584 1.0 12.598291617733178 -6.743304142261219 24.996691286345797 1.2549717245105483 1.094562819195079 0.13979271142995786 0.17381860712658373 467.79627026699586 644785.4618083127 0.05902335268727894 0.058911481005788816 1.805908980738609e-07 6.743304142261219 -0.16040890531546936 S(ph)TTELLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STTELLPR 8 0 Q9BZL6-2;Q9BZL6;Q9BZL6-3 Q9BZL6-2 PRKD2 Serine/threonine-protein kinase D2 1 S(0.983)T(0.015)T(0.002)ELLPR 98.04799999999999 0.0056258 1707900.0 7909.3 7740.2 10173.0 8118.5 8677.2 9839.5 9196.6 7066.9 7064.9 6123.4 True False 9248.188274204305 8508.595902800265 10415.56290131735 7663.6467655321285 6976.964949801394 9323.499298550212 8325.431470381904 6881.4013629994815 7168.21079702233 7233.523947192268 1.2785176826288163 1.1762725837249663 1.4399016271122194 1.0594624171399634 0.9645319488448699 1.2889290706183643 1.1509509792406876 0.9513207412094814 0.990970770174157 1.0 12.82048293910805 -6.4283319823747345 0.38369162083695907 0.9700320482229196 1.3337540268788255 0.38460089360584504 0.12315129556936114 2.155410832636873 0.5840216839610616 0.13620908201715715 0.31870256308883177 3.729649478044825e-07 6.4283319823747345 0.36372197865590594 S(ph)TTELLPR ddPTM_PC-9_Lapatinib_30min_R1 4 STTELLPR 8 0 Q9BZL6-2;Q9BZL6;Q9BZL6-3 Q9BZL6-2 PRKD2 Serine/threonine-protein kinase D2 1 S(0.972)T(0.022)T(0.007)ELLPR;S(0.983)T(0.015)T(0.002)ELLPR;S(0.93)T(0.055)T(0.014)ELLPR;S(0.965)T(0.03)T(0.005)ELLPR 121.73 0.0033594000000000002 7779200.0 38471.4 30831.800000000003 40279.8 36437.4 33586.0 34969.7 33661.0 31794.6 37519.5 31106.7 True False 37922.79078120929 30760.410861400156 36968.1503285244 39117.12794760316 31610.537512616575 33474.127449352185 35403.80187546207 33271.893187893846 33293.658812149515 36483.45164792768 1.0394518355108369 0.8431332418391777 1.0132854392526827 1.072188243730088 0.866434947484255 0.917515364839488 0.9704071373815056 0.9119721869787434 0.9125687759327084 1.0 15.15495460685311 -6.281244728226429 24.995058815848086 0.9268295040322387 0.982899659886244 0.17133344124478433 0.06560476323009685 1657.0672279571002 2091271.3555506894 0.020552008571153715 0.023332091956209097 5.233054668947991e-07 6.281244728226429 0.05607015585400521 S(ph)TTPAPK ddPTM_PC-9_Lapatinib_30min_R1 1 STTPAPK 7 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.985)T(0.014)T(0.001)PAPK 90.709 0.015746 10632000.0 63141.0 114480.0 74724.0 100570.0 131340.0 58201.0 171560.0 176130.0 110860.0 104280.0 True False 62240.597761358695 114214.92859362999 68580.48116298133 107966.25329168516 123614.83942437518 55711.87890315752 180442.5373504731 184313.64279417697 98373.77939244651 122304.65905563446 0.5088980112609318 0.9338559092967621 0.560734821490203 0.8827648441632384 1.010712432207057 0.45551722504549125 1.4753529321265892 1.507004264738072 0.8043338671807901 1.0 16.900119837160915 -7.265385824989102 24.99894987189589 1.2389231186420633 0.7475235335246948 0.4372227246705316 0.25944112877706693 316.3289406237617 2003788.4576492503 0.10314351094511774 0.07248040149662854 5.427679250011265e-08 7.265385824989102 -0.4913995851173685 S(ph)TTPPPAEPVSLPQEPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STTPPPAEPVSLPQEPPK 18 0 Q9UN86-2;Q9UN86 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 S(0.448)T(0.103)T(0.448)PPPAEPVS(0.001)LPQEPPK 89.23200000000001 0.0014611 22527000.0 69538.0 73869.0 76290.0 87854.0 95988.0 67559.0 88099.0 63169.0 63125.0 64466.0 True False 81309.40996189525 81202.22613678622 78109.04293143617 82931.82520651082 77179.8404556235 64016.087109177664 79753.62493847439 61510.880683087926 64048.08370423284 76153.17548742467 1.0677087257552647 1.066301248989877 1.0256833340368647 1.0890133559854707 1.0134815779069957 0.8406226884097403 1.0472790455290242 0.807725748655686 0.8410428494187906 1.0 16.216616576005187 -6.5929843016740675 5.589751847951256 0.9046872336617712 1.0590244452344695 0.5247487741516605 0.07015907566622465 0.16209968418106793 9.244792954482778 0.023050791041189598 0.023107920718791385 2.5527935761369474e-07 6.5929843016740675 0.1543372115726983 S(ph)TTPPPAEPVSLPQEPPKPR ddPTM_PC-9_AZD4547_30min_R2 5 STTPPPAEPVSLPQEPPKPR 20 1 Q9UN86-2 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 S(0.333)T(0.333)T(0.333)PPPAEPVSLPQEPPKPR;S(0.333)T(0.333)T(0.333)PPPAEPVS(0.001)LPQEPPKPR;S(0.333)T(0.333)T(0.333)PPPAEPVSLPQEPPKPR;S(0.364)T(0.364)T(0.272)PPPAEPVSLPQEPPKPR;S(0.333)T(0.333)T(0.333)PPPAEPVSLPQEPPKPR 152.63 9.1368e-06 1205106000.0 333931.0 337832.0 402986.0 401329.0 379759.0 390393.0 384092.0 450414.0 366258.0 373623.0 True False 440114.11180371215 447029.5873351696 397642.1423336253 308808.79952124023 327036.01796749514 365981.6639955125 418275.4439152027 380812.86578405177 385617.6501494731 360542.57249198976 1.2206994274261196 1.239880173499071 1.102899276457733 0.8565113334240191 0.9070663020655098 1.0150858509327456 1.1601277514169164 1.0562216360524592 1.0695481742535147 1.0 18.459810095891193 -5.4493148784379954 4.411740705123376 1.0115981261649187 1.2251229696690766 0.5472629441661168 0.07975206602634856 0.1864158881754463 6.77171594280186 0.024412211590563188 0.052217061338426574 3.5537356708085675e-06 5.4493148784379954 0.2135248435041579 S(ph)TTPPPAEPVSLPQEPPKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 STTPPPAEPVSLPQEPPKPR 20 1 Q9UN86-2 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 S(0.333)T(0.333)T(0.333)PPPAEPVSLPQEPPKPR;S(0.333)T(0.333)T(0.333)PPPAEPVSLPQEPPKPR;S(0.656)T(0.172)T(0.172)PPPAEPVSLPQEPPKPR;S(0.333)T(0.333)T(0.333)PPPAEPVSLPQEPPKPR;S(0.441)T(0.117)T(0.441)PPPAEPVSLPQEPPKPR;S(0.42)T(0.161)T(0.42)PPPAEPVSLPQEPPKPR;S(0.333)T(0.333)T(0.333)PPPAEPVSLPQEPPKPR 139.12 9.9475e-06 1334552000.0 301536.0 387795.0 338684.0 372420.0 413597.0 327873.0 357786.0 323481.0 316065.0 287827.0 True False 352580.08919252886 426292.724752129 346759.51102622185 351554.5148019299 332555.6368809074 310678.7626925711 323893.9199336769 314989.9665064512 320686.8526887656 340007.7566627209 1.0369766050433944 1.2537735283933555 1.0198576480424197 1.0339602785905355 0.9780825006612841 0.9137402209348906 0.9526074437618537 0.9264199428806364 0.9431751082281306 1.0 18.375208133656244 -5.789765749844305 1.4332329922440714 0.945554691082997 1.1423843188884824 0.5834795136753723 0.05977484167462185 0.2632478220574948 1.090651019579003 0.01884613044225622 0.04275569508505723 1.6226851067361552e-06 5.789765749844305 0.1968296278054854 S(ph)TTPPPAEPVSLPQEPPKPR ddPTM_PC-9_Lapatinib_30min_R1 3 STTPPPAEPVSLPQEPPKPR 20 1 Q9UN86-2 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 S(0.333)T(0.333)T(0.333)PPPAEPVSLPQEPPKPR;S(0.333)T(0.333)T(0.333)PPPAEPVSLPQEPPKPR;S(0.442)T(0.442)T(0.117)PPPAEPVSLPQEPPKPR 125.73 7.3460000000000005e-06 88301900.0 106929.0 122471.0 130099.0 112019.0 121111.0 115864.0 105581.0 109113.0 131760.0 102017.0 True False 105404.17285162292 122187.42592409575 119402.76241666297 120257.25094442973 113987.48909338728 110908.76681217583 111047.46756819938 114182.78831659007 116919.80130568959 119650.50252089227 0.8809338083073927 1.0212027810143172 0.9979294687526611 1.0050710060614372 0.9526703748986247 0.9269394150083905 0.928098630833659 0.9543026223116156 0.9771776870328992 1.0 16.868466930509854 -6.380781419045054 9.68217971403731 0.951222863181571 0.9810137981471394 0.03914095589163413 0.04084503231040041 0.8865536497843192 67.26563380428409 0.012555234740205314 0.01423363581804122 4.1611999150997997e-07 6.380781419045054 0.029790934965568394 S(ph)TTPTSSPFR ddPTM_PC-9_AZD4547_30min_R2 1 STTPTSSPFR 10 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;H7C5N8;A0A2R8Y7F4;A0A2R8YET2;A0A2R8Y424 E7EPN9 PRRC2C Protein PRRC2C 1 S(0.56)T(0.215)T(0.215)PT(0.003)S(0.006)SPFR 111.27 0.0016202999999999999 31700000.0 32796.0 30006.0 55816.0 66430.0 72057.0 57213.0 52232.0 70514.0 56235.0 61023.0 True False 43224.44580082278 39704.85270068885 55075.843370473456 51115.58983326903 62053.12934435746 53635.4620655986 56880.54681320846 59617.681550521585 59207.46729397212 58886.6033439556 0.7340285115164406 0.6742595165282927 0.9352864699764807 0.8680342714743416 1.0537732832356834 0.9108262154689892 0.9659335669434047 1.01241501742418 1.0054488445893603 1.0 15.845651838943986 -5.399770386088271 1.5832140960367982 0.9813245946653898 0.6836979707912059 0.7816290921216519 0.055307547811006816 0.19178284243554472 0.8612111203226432 0.015891374183029067 0.06039207066072973 3.983177076833143e-06 5.399770386088271 -0.2976266238741839 S(ph)TTPTSSPFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STTPTSSPFR 10 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;H7C5N8;A0A2R8Y7F4;A0A2R8YET2;A0A2R8Y424 E7EPN9 PRRC2C Protein PRRC2C 1 S(0.772)T(0.112)T(0.112)PT(0.002)S(0.001)SPFR 82.26100000000001 0.015156999999999999 4899200.0 30036.0 30217.0 47381.0 52231.0 64686.0 55781.0 52266.0 52365.0 46564.0 38314.0 True False 35120.50156195875 33216.74406280404 48510.74273344312 49304.666405186756 52011.24265233632 52855.74616316168 47314.98610692871 50990.47423530374 47244.910409566684 45260.02490654288 0.775971768342568 0.7339090981808577 1.071823155944183 1.0893645442528066 1.1491651354530623 1.1678240626756868 1.045403448288619 1.1266117139925051 1.0438551571087815 1.0 15.465949758067998 -5.282373978421659 6.199183701372531 1.09591643764606 0.7535561489146677 0.8762992095192993 0.04979035733719019 0.04465767586505995 6.987001420421613 0.012788151447587196 0.028730743657442197 5.21946538316262e-06 5.282373978421659 -0.34236028873139224 S(ph)TTQASSHNPGEPGR ddPTM_PC-9_AZD4547_30min_R2 1 STTQASSHNPGEPGR 15 0 Q9BW04 Q9BW04 SARG Specifically androgen-regulated gene protein 1 S(0.333)T(0.333)T(0.333)QASSHNPGEPGR 124.98 1.5709e-05 8372900.0 2885.5 3820.2 5101.6 10584.0 8742.5 6405.4 5129.2 7788.4 5758.5 7391.7 True False 3803.0289778715114 5055.00494191733 5033.949450673778 8144.022321169939 7528.754781534688 6004.869325415292 5585.6888634229745 6584.881739627341 6062.882553789249 7132.918832858375 0.5331658843996019 0.708686732650179 0.7057348567439851 1.1417517165138389 1.055494245476741 0.8418530290507961 0.7830859980758565 0.9231679055835521 0.8499861972156593 1.0 12.800276841554561 -5.586550339275449 8.557426064313715 0.9328812166049343 0.6421788687756964 0.6102785955390042 0.108258618093131 0.20103729915807658 24.44709654685094 0.03209461084550865 0.055751725363199375 2.5908940922097323e-06 5.586550339275449 -0.2907023478292379 S(ph)TTQASSHNPGEPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STTQASSHNPGEPGR 15 0 Q9BW04 Q9BW04 SARG Specifically androgen-regulated gene protein 1 S(0.787)T(0.191)T(0.022)QASSHNPGEPGR;S(0.333)T(0.333)T(0.333)QAS(0.001)S(0.001)HNPGEPGR 132.67 3.4242e-06 10011200.0 4419.1 5024.9 8403.599999999999 7754.1 9507.0 8245.2 5638.9 7195.0 7268.0 7047.6 True False 5167.166348796512 5523.738863592811 8603.973694830473 7319.662916131387 7644.17159657053 7812.807197154953 5104.742569899365 7006.13887373265 7374.280750294882 8325.274091229101 0.6206602079612321 0.663490331136631 1.03347632769172 0.8792098417327602 0.9181885800761646 0.9384444417735093 0.6131621030083979 0.8415505359894162 0.8857703265366222 1.0 13.02328205517002 -5.119362723509731 7.0941878667729785 0.8754045540199199 0.6315571782390202 0.45315647147418625 0.10797293950149253 0.2257485016453725 11.996238936828103 0.028508078735996978 0.0770539839767702 7.59691516219389e-06 5.119362723509731 -0.24384737578089966 S(ph)TTQASSHNPGEPGR ddPTM_PC-9_Lapatinib_30min_R1 2 STTQASSHNPGEPGR 15 0 Q9BW04 Q9BW04 SARG Specifically androgen-regulated gene protein 1 S(0.956)T(0.044)TQASSHNPGEPGR;S(0.434)T(0.434)T(0.124)QAS(0.004)S(0.005)HNPGEPGR 187.56 3.0969e-07 7039100.0 10547.7 5217.9 14920.7 10158.4 10357.5 12574.5 8592.8 7615.4 15553.5 9645.1 True False 10397.28786378872 5205.818273136818 13693.9776415676 10905.482623429001 9748.292213628485 12036.717947591176 9037.69313910669 7969.239285384528 13801.701044384057 11312.242683712102 0.919118176164946 0.46019329841927803 1.2105448958662133 0.9640424916918753 0.861747089961616 1.0640434690215945 0.7989302733152627 0.7044791654672519 1.2200676232181966 1.0 13.465597355554833 -5.258648651041701 24.99998308157928 0.9594574085232466 0.6896557633595584 0.2716884286890173 0.18686943265394473 320.6661011120955 2872562.155428743 0.046562718678119744 0.11246802847352817 5.5125348612122735e-06 5.258648651041701 -0.2698016451636882 S(ph)TTTGHLIYK ddPTM_PC-9_AZD4547_30min_R2 3 STTTGHLIYK 10 0 Q5VTE0;P68104;A0A087WVQ9;A0A087WV01;A0A2U3TZH3;Q05639;A6PW80;Q5JR01;A0A2R8Y660;A0A2R8Y488;A0A2R8YDN5 Q5VTE0 EEF1A1P5;EEF1A1;EEF1A2 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha;Elongation factor 1-alpha 2 1 S(0.278)T(0.278)T(0.278)T(0.166)GHLIYK;S(0.25)T(0.25)T(0.25)T(0.25)GHLIYK;S(0.25)T(0.25)T(0.25)T(0.25)GHLIYK 72.34 0.017465 21234400.0 62809.0 94031.0 165190.0 230196.0 195342.0 195181.0 90553.0 220897.0 142658.0 142658.0 True False 82780.95549164157 124424.68187357431 162999.47266677144 177127.86869274706 168222.1351483611 182976.30121520642 98612.04157559472 186762.44435807862 150198.61063792076 137663.5868417156 0.6013278993436543 0.9038314686412809 1.1840420288786084 1.28667189891258 1.221979893214474 1.329155410032945 0.716326254734144 1.3566582757488113 1.0910554786765643 1.0 17.07078747958881 -4.933716308992016 2.450019542752417 1.159242698226897 0.5617255595614474 0.4803924715480913 0.17804417843935597 0.32315925890392766 3.1081812233371093 0.046313902634228986 0.35881191838048704 1.1648867113625702e-05 4.933716308992016 -0.5975171386654496 S(ph)TVLGLPQHVQK ddPTM_PC-9_AZD4547_30min_R2 1 STVLGLPQHVQK 12 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 S(0.81)T(0.19)VLGLPQHVQK 85.287 0.0055243 36978000.0 207070.0 206750.0 279240.0 336420.0 320660.0 311080.0 286120.0 363440.0 263900.0 300340.0 True False 272913.952676435 273577.8942833903 275537.0951478255 258863.5666371874 276141.89399449935 291628.1184235479 311584.1257121158 307278.69902035856 277849.215237472 289825.18801638146 0.941650222136695 0.9439410568688295 0.9507009968100206 0.8931713920687803 0.9527877679799566 1.0062207512725378 1.0750760754945303 1.0602208218113554 0.9586786336243743 1.0 18.144823455968044 -6.777178344892535 3.366841045606117 1.0296031687291591 0.9336131280060787 0.6127007041993741 0.03345312080206412 0.15396565780354318 3.6469091407655423 0.012296006606392327 0.011346258424079598 1.6704045146638768e-07 6.777178344892535 -0.09599004072308048 S(ph)TVLGLPQHVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 STVLGLPQHVQK 12 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 S(0.5)T(0.5)VLGLPQHVQK;S(0.5)T(0.5)VLGLPQHVQK;S(0.5)T(0.5)VLGLPQHVQK 100.11 0.0017767 35323200.0 143242.0 165026.0 156812.0 149167.0 195368.0 125014.0 123760.0 117507.0 108706.0 106144.0 True False 167490.04144154006 181408.69066116124 160550.99279282131 140809.65659593928 157087.04286092243 118458.04576543062 112036.5568551924 114422.5657589578 110295.61959845283 125387.06696455856 1.3357840285783396 1.4467894899594194 1.2804430048451652 1.122999843642088 1.2528169504541011 0.9447389482275196 0.8935256208430191 0.9125547676404303 0.8796411166522348 1.0 16.936029023626823 -6.328828865293344 0.8373524316405042 0.8965957174463283 1.3960085846501327 0.845003602142067 0.07797264741064054 0.22943541051348018 0.34959088203735783 0.04253242211769773 0.06568823891823924 4.689981555041322e-07 6.328828865293344 0.4994128672038044 S(ph)TVLGLPQHVQK ddPTM_PC-9_Lapatinib_30min_R1 2 STVLGLPQHVQK 12 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 S(0.5)T(0.5)VLGLPQHVQK;S(0.5)T(0.5)VLGLPQHVQK 78.508 0.009293299999999999 67497000.0 323230.0 269224.0 304800.0 266491.0 252719.0 231662.0 204343.0 179126.0 280687.0 181395.0 True False 318620.6809268783 268600.6283690731 279740.5205620247 286089.63712791493 237854.56528467068 221754.35629049782 214922.88068202196 187448.84789161265 249073.07429485503 212748.8840563555 1.4976373781705863 1.2625242645123482 1.3148859595800448 1.3447292022087975 1.1180061711706317 1.0423291161976522 1.010218604131858 0.881080287321079 1.1707373949321283 1.0 17.698792038918747 -6.406600909424502 1.9472718532639663 1.008604641762943 1.3546848647810592 0.7697766855970365 0.08636726448082342 0.15652029233098302 1.1750650871205344 0.030205619826424196 0.03553775547555867 3.921020298462455e-07 6.406600909424502 0.34608022301811614 S(ph)VASSQPAKPTK ddPTM_PC-9_AZD4547_30min_R2 2 SVASSQPAKPTK 12 1 A0A087X0K9;G5E9E7;Q07157-2;H0YKB1;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 S(0.726)VAS(0.234)S(0.033)QPAKPT(0.006)K;S(1)VASSQPAKPTK 78.615 0.0076821 59111500.0 193137.0 192749.0 262022.0 298870.0 298520.0 289950.0 210889.0 284830.0 250671.0 323458.0 True False 254550.54850083872 255051.3448378679 258547.41707786627 229970.1389954703 257075.65083028137 271819.380663841 229657.7124538737 240816.06824226512 263920.9573050106 312133.8338729521 0.8155173226252956 0.8171217508630657 0.828322306075614 0.736767738831783 0.8236071291615216 0.87084241170241 0.7357668010682602 0.7715154273864606 0.8455378067487371 1.0 18.251805221681536 -8.637414699138406 4.6586081647344635 0.9999895754361653 0.8006256698466212 0.6944437394602851 0.03982981442461156 0.5039107315316156 19.819784878689138 0.03941600040086874 0.010269748983109561 2.304545573146232e-09 8.637414699138406 -0.1993639055895441 S(ph)VASSQPAKPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVASSQPAKPTK 12 1 A0A087X0K9;G5E9E7;Q07157-2;H0YKB1;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 S(0.994)VAS(0.006)SQPAKPTK;S(0.985)VAS(0.015)S(0.001)QPAKPTK 74.85300000000001 0.0096171 49742000.0 87471.0 96090.0 115704.0 122656.0 116975.0 126792.0 123911.0 100881.0 110625.0 96518.0 True False 102278.11266900029 105629.18016331327 118462.8221698637 115783.9819761173 94054.58846206333 120142.80431544058 112173.25304204713 98232.9806422549 112242.68134306167 114015.94936393255 0.8970509234855752 0.9264421403548623 1.0390021995233052 1.0155068884840075 0.8249248371545487 1.0537368235381828 0.9838382583124082 0.8615722729168417 0.9844471933026606 1.0 16.798876127412527 -5.011031967584688 23.470800828802492 0.9664702941379005 0.9043986334831403 0.10683395966581288 0.06937050411576436 534.7079185783392 1137648.8085922592 0.01752542847823791 0.054067478740622045 9.749178732395276e-06 5.011031967584688 -0.06207166065476022 S(ph)VASSQPAKPTK ddPTM_PC-9_Lapatinib_30min_R1 2 SVASSQPAKPTK 12 1 A0A087X0K9;G5E9E7;Q07157-2;H0YKB1;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 S(0.713)VAS(0.257)S(0.007)QPAKPT(0.023)K;S(0.998)VAS(0.002)SQPAKPTK 74.296 0.009903700000000001 60429000.0 277480.0 230630.0 261210.0 241960.0 266500.0 241940.0 226670.0 239550.0 262910.0 212390.0 True False 273523.0843163998 230095.99040486463 239734.32209975843 259754.54555489848 250824.99395915892 231592.79018968623 238405.86349517212 250680.36752026927 233298.30723496384 249101.32850811406 1.0980394442476458 0.9237043888241232 0.9623968026808395 1.042766600686505 1.0069195353608429 0.9297131877084408 0.957063797784629 1.0063389425564777 0.9365598675535146 1.0 17.926373190222535 -6.716611648119589 24.948291756188212 0.9657767610145919 1.0016860465692188 0.14575146257367266 0.04865224816287314 296.8635431461348 165214.4528130156 0.015956730957563572 0.01595665115670722 1.920385207010939e-07 6.716611648119589 0.03590928555462691 S(ph)VAVSDEEEVEEEAER ddPTM_PC-9_Lapatinib_30min_R1 1 SVAVSDEEEVEEEAER 16 0 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 S(0.624)VAVS(0.376)DEEEVEEEAER 184.01 7.8952e-08 7067300.0 32425.0 32006.0 32729.0 28728.0 25048.0 20783.0 18082.0 15560.0 18146.0 12330.0 True False 31962.613553983265 31931.892073442792 30038.147957593512 30840.75295379867 23574.72588626274 19894.159537539268 19018.1974840945 16282.974404572735 16102.20639414879 14461.224071307723 2.2102287742985576 2.2081043704176007 2.0771511325373697 2.132651620756593 1.6302026557376263 1.3756898751752933 1.3151167142087365 1.1259748361744506 1.1134746488090808 1.0 13.819902054028194 -6.600523372146435 0.9495619897571267 1.087478329116126 2.2334038409281765 0.977833023339129 0.06989385571129625 0.07281133406869218 0.1428303304197896 0.03864990816804334 0.04205223693591245 2.508861158067083e-07 6.600523372146435 1.1459255118120504 up S(ph)VDALDDLTPPSTAESGSR ddPTM_PC-9_AZD4547_30min_R2 5 SVDALDDLTPPSTAESGSR 19 0 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 1 S(1)VDALDDLTPPSTAESGSR;S(1)VDALDDLTPPSTAESGSR;S(1)VDALDDLTPPSTAESGSR;S(1)VDALDDLTPPSTAESGSR;S(1)VDALDDLTPPSTAESGSR 205.15 2.1872e-20 19580500.0 18018.55 34978.9 33932.1 20838.0 23927.6 19649.89 30931.04 32480.3 26204.1 23268.4 True False 23748.074090877406 46285.145375329084 33482.1381831597 16034.1210438907 20605.665760440286 18421.17927198689 33683.84263863575 27461.215958042467 27589.195229269564 22453.780398349754 1.0576425737477497 2.06135201085029 1.4911581742208755 0.7140944980948122 0.9176924952002605 0.8204043570917242 1.5001412698020042 1.2230108013375216 1.2287104772476192 1.0 14.454670742235328 -5.586326277788837 8.720542942831617 1.0709727738549266 1.6132260320741267 0.33221387398314506 0.3099133289094026 0.2956319132940534 37.06849043683422 0.08507562073227788 0.14774093185344928 2.592231132819101e-06 5.586326277788837 0.5422532582192001 S(ph)VDALDDLTPPSTAESGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SVDALDDLTPPSTAESGSR 19 0 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 1 S(1)VDALDDLTPPSTAESGSR;S(1)VDALDDLTPPSTAESGSR;S(1)VDALDDLTPPSTAESGSR;S(1)VDALDDLTPPSTAESGSR;S(1)VDALDDLTPPSTAESGSR 246.42 9.651599999999998e-54 18211900.0 18321.800000000003 32091.800000000003 22744.3 11265.73 31392.3 16486.19 19867.81 14543.9 14623.989999999998 13476.77 True False 21423.318867954997 35277.66181668247 23286.610370238093 10634.54767208946 25241.20416651112 15621.62517412119 17985.787206311932 14162.138035535825 14837.838187879035 15920.001718947387 1.345685713240707 2.2159332919352845 1.4627266241135668 0.6679991535071647 1.5855026030851485 0.9812577567456491 1.1297603809242007 0.8895814388437271 0.9320249111669127 1.0 13.958552871204676 -5.529855563060406 13.586161796438905 1.049002586487516 1.795470684665063 0.5224033563706372 0.29405829408271433 0.4560520481881789 884.7451577163503 0.07489993127846208 0.1321107539340867 2.9521908981760445e-06 5.529855563060406 0.7464680981775469 S(ph)VDALDDLTPPSTAESGSR ddPTM_PC-9_Lapatinib_30min_R1 5 SVDALDDLTPPSTAESGSR 19 0 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 1 S(1)VDALDDLTPPSTAESGSR;S(1)VDALDDLTPPSTAESGSR;S(1)VDALDDLTPPSTAESGSR;S(1)VDALDDLTPPSTAESGSR;S(1)VDALDDLTPPSTAESGSR 187.75 5.1476000000000004e-11 15134660.0 22599.8 48887.41 17141.75 14813.099999999999 24057.1 16481.260000000002 18577.980000000003 20279.68 27972.79 12179.45 True False 22277.522707704273 48774.21420577854 15732.421484068525 15902.504789053015 22642.108676078384 15776.394929493545 19539.85690164572 21221.94796741166 24822.19982366259 14284.651704402993 1.5595425893959751 3.4144489634804844 1.1013514231655563 1.1132581401443165 1.5850655055943261 1.104429793316609 1.3678917278482121 1.4856468611601055 1.737683237737717 1.0 13.80217823973298 -5.285877862815075 24.924223004491974 1.326509660232199 2.486996048998927 0.49687191078568216 0.47279933007710045 484.608589882848 494239.94818497606 0.11443526467729744 0.23839545571279003 5.177524196437252e-06 5.285877862815075 1.160486388766728 S(ph)VDAYDSYWESR ddPTM_PC-9_Lapatinib_30min_R1 2 SVDAYDSYWESR 12 0 Q9UM82 Q9UM82 SPATA2 Spermatogenesis-associated protein 2 1 S(1)VDAYDSYWESR;S(1)VDAYDSYWESR 175.74 0.00037460000000000005 6519300.0 13561.8 15663.9 12308.900000000001 12841.1 11306.2 10274.6 13345.9 9853.7 15304.4 14051.9 True False 13368.406245070468 15627.63120193715 11296.909755728035 13785.477330653855 10641.191544844452 9835.179309262425 14036.88540000978 10311.53887470041 13580.657309523342 16480.752192020194 0.8111526761225928 0.9482353123120123 0.6854608105325362 0.8364592325663774 0.6456739001267675 0.5967676229016121 0.8517138803170823 0.6256716170814793 0.8240314004659904 1.0 14.008494469093197 -5.2646603583505 24.997212830268627 0.7412007726576836 0.8796939950639825 0.12360211751695072 0.12286633224944883 432.4305188314761 3356015.0735606663 0.029945817521697175 0.06690504970745756 5.436753486495182e-06 5.2646603583505 0.1384932224062989 S(ph)VDEIAK ddPTM_PC-9_Lapatinib_30min_R1 2 SVDEIAK 7 0 A6ND36;A6ND36-2 A6ND36 FAM83G Protein FAM83G 1 S(1)VDEIAK;S(1)VDEIAK 107.15 0.0099493 13436900.0 62862.0 79374.0 83674.0 92933.0 82964.0 81460.0 76148.0 79077.0 95808.0 107782.0 True False 61965.57635252104 79190.2143797241 76794.64671098033 99767.6028354001 78084.22063349979 77976.14569253476 80090.57084497451 82751.20610478155 85017.09413703342 126411.97508951268 0.4901875499425038 0.6264455113817285 0.6074950308829667 0.7892258843733307 0.617696389746368 0.6168414474761559 0.6335679099093433 0.6546152454795932 0.6725398766757071 1.0 16.94777361187529 -14.522878745136865 0.2650071278526691 3.414185376219785 0.610388703344267 0.7386656122532385 0.06633427696379705 107.61026661169711 1.0500907510762623 141.76456959953006 0.08746667727491783 3.000000000991076e-15 14.522878745136865 -2.803796672875518 S(ph)VDEVNYWDK ddPTM_PC-9_AZD4547_30min_R2 2 SVDEVNYWDK 10 0 F5H5P2;P12694;P12694-2;F5GXU9 F5H5P2 BCKDHA 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 1 S(1)VDEVNYWDK;S(1)VDEVNYWDK 156.08 0.00031038 22350000.0 78735.0 132224.0 88127.0 52021.0 59388.0 106145.0 104807.0 117811.0 117105.0 73136.0 True False 103771.09221026277 174962.82221875206 86958.3783988411 40028.36216643813 51143.0013114992 99507.7363702825 114134.61996193776 99606.01697745828 123294.93122540429 70575.53090086581 1.4703551058797593 2.479086164644149 1.2321321184390028 0.5671705427574342 0.7246562747553031 1.4099466925733286 1.6171981776836706 1.4113392518062706 1.7469926141765904 1.0 16.1068804558658 -6.991676734488167 24.98702008302962 1.4832196877387105 1.2916596960153066 0.017042500558259288 0.5116667928926159 1007.5051466735961 3024584.525939665 0.20310459783616253 0.17884055275835833 1.019349855080618e-07 6.991676734488167 -0.19155999172340388 S(ph)VDEVNYWDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SVDEVNYWDK 10 0 F5H5P2;P12694;P12694-2;F5GXU9 F5H5P2 BCKDHA 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 1 S(1)VDEVNYWDK;S(1)VDEVNYWDK;S(1)VDEVNYWDK;S(1)VDEVNYWDK 164.68 7.7667e-05 17817700.0 75512.7 119932.0 96055.0 69474.5 96628.0 60115.0 86517.0 60277.0 60333.0 62475.7 True False 88295.50866619116 131838.0563570243 98345.31549061627 65582.06900436817 77694.43704990199 56962.46357359068 78321.48343116255 58694.79261876065 61215.25598617791 73802.04985263095 1.1963828761193078 1.786373909942617 1.332555338056242 0.8886212393195505 1.052740909026828 0.7718276617971206 1.0612372364664133 0.795300303121164 0.8294519746865223 1.0 16.171373267259987 -5.659816731393331 3.9599602575346755 0.9107007955169141 1.50589711679009 0.6864841878473626 0.16405715757765582 0.10928188819107776 3.1687429608804694 0.042712072539199154 0.0769058141773583 2.1886850357162192e-06 5.659816731393331 0.595196321273176 S(ph)VDEVNYWDKQDHPISR ddPTM_PC-9_AZD4547_30min_R2 2 SVDEVNYWDKQDHPISR 17 1 F5H5P2;P12694;P12694-2 F5H5P2 BCKDHA 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 1 S(0.999)VDEVNY(0.001)WDKQDHPISR;S(1)VDEVNYWDKQDHPISR 108.47 0.0002201 22860700.0 100688.0 113167.0 125820.0 138444.0 148796.0 150317.0 137557.0 171145.0 153728.0 123900.0 True False 132704.6895594962 149746.01964869886 124151.54459067246 106527.87473847804 128138.24380591762 140917.65422744103 149799.30651678133 144698.47277085457 161853.74823806775 119562.29871222503 1.109920861248274 1.2524518285577892 1.0383837206868471 0.8909821564645591 1.0717278371699264 1.1786127880212163 1.2528975114248504 1.2102349513965927 1.3537189396770815 1.0 16.867403014177093 -6.859976304303361 3.9192953259452183 1.2208218901874448 1.070555257859786 0.2241065631626299 0.11646660199319538 0.33046489524185124 9.52870697075876 0.04416350343857915 0.03906784826515745 1.3804595822974148e-07 6.859976304303361 -0.1502666323276589 S(ph)VDEVNYWDKQDHPISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SVDEVNYWDKQDHPISR 17 1 F5H5P2;P12694;P12694-2 F5H5P2 BCKDHA 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 1 S(1)VDEVNYWDKQDHPISR;S(1)VDEVNYWDKQDHPISR;S(1)VDEVNYWDKQDHPISR 85.177 0.0013819000000000001 18566800.0 141689.4 118093.0 149863.0 159262.0 199369.0 166227.0 164095.0 134915.0 135276.0 147824.0 True False 165674.6169267876 129816.49259055195 153436.30227859263 150339.06647437037 160304.07563234188 157509.76349409073 148550.73365508072 131373.62420425873 137254.15558295127 174623.3210258596 0.9487542440121912 0.743408680054411 0.8786701648851963 0.8609334972624131 0.9179992379631973 0.9019972966312183 0.8506924091375067 0.7523257685885145 0.786001289957288 1.0 17.41388671886576 -10.168223790750872 7.897675315947921 1.000000000035018 0.8478933770594247 0.32290868454136734 0.0655903350013156 0.0 0.0 0.06525067397227007 0.01582561299590651 6.788537310146157e-11 10.168223790750872 -0.1521066229755933 S(ph)VDEVNYWDKQDHPISR ddPTM_PC-9_Lapatinib_30min_R1 2 SVDEVNYWDKQDHPISR 17 1 F5H5P2;P12694;P12694-2 F5H5P2 BCKDHA 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 1 S(1)VDEVNYWDKQDHPISR;S(0.996)VDEVNY(0.004)WDKQDHPISR 104.68 0.00032559 18047600.0 129244.0 109922.0 80294.0 78855.0 82562.0 61917.0 58906.0 55553.0 101903.0 63423.0 True False 127400.95685955345 109667.48236258766 73692.53726380318 84654.25975256853 77705.86548313727 59268.954245576584 61955.8644507284 58134.195186197256 90425.61105383799 74385.58104416463 1.712710381114214 1.4743110267227093 0.9906830897785154 1.1380466289872377 1.044636129641863 0.7967801476254798 0.8329015325422222 0.7815250532449493 1.2156335916788763 1.0 16.18273537491366 -4.761566281698131 0.9224146525473522 0.9260215379697855 2.2214589717207485 0.7688469278844325 0.1376797808943768 1.014924433079904 0.6598836609525622 0.048418640617398846 1.341003587744731 1.7315447435227763e-05 4.761566281698131 1.2954374337509629 S(ph)VDFDSLTVR ddPTM_PC-9_AZD4547_30min_R2 4 SVDFDSLTVR 10 0 Q9Y5K6 Q9Y5K6 CD2AP CD2-associated protein 1 S(1)VDFDSLTVR;S(1)VDFDSLTVR;S(0.996)VDFDS(0.004)LTVR;S(0.998)VDFDS(0.002)LTVR 160.72 0.00014008 31255600.0 33569.6 22639.300000000003 33210.6 44521.5 50454.8 39872.2 30901.6 38063.899999999994 35804.2 38320.5 True False 44244.03450894317 29957.010989358958 32770.20574457946 34257.75602531812 43450.02193324293 37378.98503088391 33651.78253566858 32181.998876406084 37696.736916277 36978.91095885244 1.1964666714543015 0.810110687756409 0.8861863395880931 0.9264133295714894 1.1749946336059247 1.0108189792954327 0.9100263275225694 0.870279790343636 1.0194117657554411 1.0 15.174415117071488 -4.736507056773989 24.64683459537653 0.9563576685607216 1.1964679862086605 0.35688378317191494 0.09665066173807689 2459.414602931908 2431102.212099448 0.025792902702214182 1.7442964733754383 1.834395360110797e-05 4.736507056773989 0.2401103176479389 S(ph)VDFDSLTVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SVDFDSLTVR 10 0 Q9Y5K6 Q9Y5K6 CD2AP CD2-associated protein 1 S(0.997)VDFDS(0.003)LTVR;S(0.999)VDFDS(0.001)LTVR;S(1)VDFDSLTVR;S(1)VDFDSLTVR 158.06 0.00011211 18411100.0 18052.300000000003 21227.1 25088.999999999996 26995.399999999998 34826.8 31751.699999999997 37904.9 31110.6 30806.2 20808.8 True False 21108.197840822602 23334.386202983333 25687.216910562336 25482.93525826764 28002.738546275654 30086.58495632671 34314.273464288875 30293.97971440544 31256.68239539544 24581.27071762982 0.8587106046427326 0.9492750180017253 1.0449914166617646 1.0366809572619506 1.1391900308144745 1.2239637772163035 1.395951977359677 1.2324008820536048 1.2715649550606014 1.0 14.58527187665292 -5.958377921198698 0.962233409158362 1.2499603028601167 0.893479506185043 0.6106442656254352 0.09808583740863672 0.3873096074948991 0.7191131653783295 0.04138056524715524 0.09594132733645065 1.1005811716947363e-06 5.958377921198698 -0.3564807966750737 S(ph)VDFDSLTVR ddPTM_PC-9_Lapatinib_30min_R1 2 SVDFDSLTVR 10 0 Q9Y5K6 Q9Y5K6 CD2AP CD2-associated protein 1 S(1)VDFDSLTVR;S(1)VDFDSLTVR 149.94 0.00015853 12279900.0 20739.9 17844.9 22496.8 15632.300000000001 17888.7 18211.0 18493.4 16111.3 17219.699999999997 19708.6 True False 20444.145222768155 17803.581230437394 20647.199944159307 16781.951489824107 16836.521836537384 17432.157981914428 19450.897763098856 16859.88981519232 15280.23605452021 23115.205249941235 0.8844457577472788 0.7702108217482799 0.8932302231757946 0.7260135183037915 0.7283743170128324 0.7541424700072151 0.8414763162506769 0.7293852523864214 0.6610469554259769 1.0 14.49655455249569 -11.55488090907062 2.76918575470641 1.2738550612165982 0.776700288713262 0.4712331419578276 0.0710310979166428 112461367.82466026 107208633.17539963 194214257.9172189 0.0179942921115793 2.7868852751753612e-12 11.55488090907062 -0.4971547725033362 S(ph)VDFHFR ddPTM_PC-9_AZD4547_30min_R2 1 SVDFHFR 7 0 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 S(1)VDFHFR 76.465 0.022739 0.0 7040.1 7762.0 8469.5 8990.9 6403.3 10911.0 6880.9 8393.3 7860.7 6528.7 True False 9278.705356823157 10270.914705817066 8357.18889612701 6918.1869130202895 5514.31232400355 10228.733445156637 7493.286769930424 7096.3083438465155 8276.200554062885 6300.1322001816225 1.4727794690650566 1.630269711724616 1.3265100843258633 1.0981018640880027 0.875269303689307 1.6235744140197184 1.18938564014806 1.1263745137986059 1.3136550616865303 1.0 12.62116638669454 -5.465413381574652 4.266540718172723 1.1878722011191762 1.5461477617974442 0.37903370534276704 0.19079411485447328 0.23216627113903657 8.539916398038217 0.05178312774713651 0.10986964153948185 3.4244167954017437e-06 5.465413381574652 0.35827556067826793 S(ph)VDIHDSIQPR ddPTM_PC-9_AZD4547_30min_R2 1 SVDIHDSIQPR 11 0 E5RHL7;E5RIF2;Q9Y6D6 E5RHL7 ARFGEF1 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 1 S(0.999)VDIHDS(0.001)IQPR 66.708 0.023534 5652900.0 4335.9 9553.6 29281.0 76720.0 36830.0 33746.0 18565.0 57117.0 23862.0 31338.0 True False 5714.626007677384 12641.614369169534 28892.714808134486 59033.38931218416 31716.79023207576 31635.857285331847 20217.249034829514 48290.880068087805 25123.296604761483 30240.866158544817 0.1889703151264623 0.4180308296360598 0.9554195523586417 1.952106431167937 1.0488056150836773 1.046129337680788 0.6685406736975011 1.5968748981894754 0.8307730497217481 1.0 14.884211841355178 -5.272646754515844 3.480366907833067 1.1742889688550209 0.2612701301061716 0.4798701430514657 0.35298755867760867 0.19120329624873533 4.957099395235319 0.09449759841109243 0.2548169475762105 5.337688747147061e-06 5.272646754515844 -0.9130188387488493 S(ph)VDIHDSIQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVDIHDSIQPR 11 0 E5RHL7;E5RIF2;Q9Y6D6 E5RHL7 ARFGEF1 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 1 S(1)VDIHDSIQPR 70.41199999999999 0.018298 2531100.0 9606.2 9489.9 24382.0 14612.0 26381.0 26982.0 15364.0 12999.0 18317.0 12674.0 True False 11232.33992890159 10431.994555435816 24963.359349249924 13793.337012743163 21211.832427593064 25567.016420903667 13908.610694272626 12657.79002357898 18584.85147264052 14971.695872671202 0.7502383179853862 0.6967810890734166 1.6673701871554276 0.9212942294614084 1.4167955726586983 1.707690073211598 0.928993669959654 0.8454479793891657 1.2413324202346805 1.0 13.869950027032647 -5.215425764579335 24.993277203831656 1.2145355984338344 0.7235091029781614 0.3158118197656101 0.29001594951393705 522.0644732489869 283568.74671058985 0.07551303663130922 0.19978699727958363 6.089396249698838e-06 5.215425764579335 -0.491026495455673 S(ph)VDISLGDSPR ddPTM_PC-9_AZD4547_30min_R2 2 SVDISLGDSPR 11 0 H0YDE2;A0A1B0GTN9;E9PKC0;Q6IQ23-3;Q6IQ23;Q6IQ23-2 H0YDE2 PLEKHA7 Pleckstrin homology domain-containing family A member 7 1 S(0.993)VDISLGDS(0.007)PR;S(0.959)VDISLGDS(0.041)PR 124.38 0.0016577000000000002 2894300.0 26625.0 26912.0 36859.0 54760.0 46057.0 43431.0 33866.0 45090.0 36940.0 41197.0 True False 35091.196165596586 35610.777707156485 36370.22557675724 42135.92803356629 39662.780551689204 40715.252704298226 36880.00839286483 38122.376565122104 38892.57298549534 39754.70556939088 0.882692895419531 0.8957625819916772 0.9148659273371775 1.0598978769951912 0.9976876946669566 1.0241618475385446 0.9276891342709523 0.9589399800378453 0.978313697169994 1.0 15.27883801478509 -5.580324540063363 9.304509790445795 0.9895077349786029 0.8932010109778916 0.6281595054923016 0.033663914678122485 0.2228628944114052 33.938627114488995 0.009843756703892237 0.01708468912504149 2.6283031765317347e-06 5.580324540063363 -0.09630672400071127 S(ph)VDISLGDSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVDISLGDSPR 11 0 H0YDE2;A0A1B0GTN9;E9PKC0;Q6IQ23-3;Q6IQ23;Q6IQ23-2 H0YDE2 PLEKHA7 Pleckstrin homology domain-containing family A member 7 1 S(0.958)VDIS(0.002)LGDS(0.04)PR 79.283 0.017450999999999998 3392900.0 11586.0 14155.0 14513.0 17195.0 21977.0 17477.0 18153.0 20497.0 16368.0 15102.0 True False 13547.28096606919 15560.21485286398 14859.044960858995 16231.619896942151 17670.764613214546 16560.475353499874 16433.416423661216 19958.975468366654 16607.351034786272 17839.873052633782 0.7593821394412412 0.8722155593235431 0.8329120345766858 0.9098506390181853 0.9905207599336436 0.928284372015471 0.9211621840120143 1.1187846129555288 0.930911951323244 1.0 14.122817728720934 -4.893237375555394 0.409758964575958 1.012754092673845 0.62104252409115 0.6245865958391206 0.05696436486669137 3.327068709901926 0.4711904133561987 0.046099645758495865 0.6368583796512122 1.2786822143018936e-05 4.893237375555394 -0.39171156858269496 S(ph)VEAAAELSAK ddPTM_PC-9_Lapatinib_30min_R1 2 SVEAAAELSAK 11 0 P20962;F5H7R9;F5GXR3 P20962 PTMS Parathymosin 1 S(1)VEAAAELSAK;S(1)VEAAAELSAK 164.13 0.00082363 6701300.0 26261.7 33253.0 27541.6 26458.0 27704.0 30552.0 30733.0 33438.0 29259.0 24247.0 True False 25887.203342194058 33176.004721558216 25277.23596165047 28403.809581300637 26074.505188159637 29245.362180190506 32324.204362276083 34991.65155142051 25963.543309070847 28438.061642903373 0.9103012598840092 1.166605696905407 0.8888522811103169 0.9987955556875557 0.9168875683433384 1.0283880296563248 1.1366528692486495 1.2304513574381595 0.912985689218026 1.0 14.79553551280942 -7.004722236641803 23.859489337560003 1.088268729744553 0.9821928011903719 0.13764533872603013 0.10653723523825259 195.93107422626298 989965.3967261834 0.037080128436109076 0.03182374449111214 9.891855495137299e-08 7.004722236641803 -0.10607592855418113 S(ph)VEDDEEGHLICQSGDVLSAR ddPTM_PC-9_AZD4547_30min_R2 2 SVEDDEEGHLICQSGDVLSAR 21 0 F8WBF5;P49759;P49759-3 F8WBF5 CLK1 Dual specificity protein kinase CLK1 1 S(1)VEDDEEGHLICQSGDVLSAR;S(1)VEDDEEGHLICQSGDVLSAR 106.1 4.3948999999999995e-05 10487400.0 16402.8 11153.0 19701.1 21965.5 21770.0 19129.3 17621.4 22523.2 19619.5 17200.1 True False 21618.54920056519 14757.98914119784 19439.85054152994 16901.693338592035 18747.611277553337 17933.141846983304 19189.670462824917 19042.756971646886 20656.546715996905 16597.929734302987 1.3024846801156216 0.8891463801474869 1.1712214024712702 1.0183012947489023 1.1295150405901284 1.080444497238763 1.156148433570337 1.147297119368518 1.2445254948456592 1.0 14.01871568447607 -7.263126197531734 23.849269003336545 1.1492675244916484 1.0900692724203538 0.018986932120745093 0.11414084945135189 256.4033888312241 3625126.5000587124 0.04258113947647907 0.030407203613581762 5.45599297507775e-08 7.263126197531734 -0.05919825207129459 S(ph)VEDDEEGHLICQSGDVLSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVEDDEEGHLICQSGDVLSAR 21 0 F8WBF5;P49759;P49759-3 F8WBF5 CLK1 Dual specificity protein kinase CLK1 1 S(1)VEDDEEGHLICQSGDVLSAR;S(1)VEDDEEGHLICQSGDVLSAR 146.45 1.2620999999999998e-05 9195800.0 13623.3 13552.2 17107.0 16525.9 17230.8 18961.4 16909.3 16186.1 14370.599999999999 13581.1 True False 15929.455617560017 14897.572852630401 17514.89575865878 15600.007400690702 13854.548432332762 17967.03080436301 15307.528691269454 15761.232025590567 14580.74283849582 16043.245922071545 0.9929072766780331 0.9285884493071953 1.0917301800231465 0.9723722665890787 0.8635751455553221 1.1199124473710655 0.9541416223141026 0.9824216434846893 0.9088399510498258 1.0 13.96967844166126 S(ph)VEDDEEGHLICQSGDVLSAR ddPTM_PC-9_Lapatinib_30min_R1 2 SVEDDEEGHLICQSGDVLSAR 21 0 F8WBF5;P49759;P49759-3 F8WBF5 CLK1 Dual specificity protein kinase CLK1 1 S(1)VEDDEEGHLICQSGDVLSAR;S(1)VEDDEEGHLICQSGDVLSAR 122.44 7.9417e-07 11551300.0 20041.7 16032.6 20828.1 17868.4 21886.7 19004.0 18454.4 18966.2 22082.0 15375.7 True False 19755.901682802352 15995.477499739998 19115.694016791025 19182.501743235018 20599.367336907795 18191.243220487722 19409.878533927313 19847.43889151719 19594.89262623133 18033.369258167582 1.0955191678257579 0.8869932884280849 1.0600178892323875 1.0637225616919577 1.1422916617524501 1.00875454608953 1.0763312310668895 1.1005951581969626 1.0865907721241004 1.0 14.138381346920786 -5.491945343930956 24.76616053223704 1.0725604321234357 0.9868185415078728 0.19794268975190776 0.06087255727146042 757.6916531693905 606627.9598730837 0.014813633562982494 0.030774035281278242 3.221474189104686e-06 5.491945343930956 -0.08574189061556281 S(ph)VEDDKEGHLVCR ddPTM_PC-9_Lapatinib_30min_R1 2 SVEDDKEGHLVCR 13 1 H3BUL5;H3BVF8;H3BQG1;P49761-3;P49761-1;P49761 H3BUL5 CLK3 Dual specificity protein kinase CLK3 1 S(1)VEDDKEGHLVCR;S(1)VEDDKEGHLVCR 62.68 0.020429 13537700.0 39137.0 54018.0 58896.0 48766.0 51928.0 60541.0 48380.0 57349.0 62651.0 45566.0 True False 38578.89920315322 53892.92463985603 54053.79822513455 52352.414318607145 48873.69713437604 57951.80255796392 50884.87967484196 60013.6439028176 55594.584635722225 53442.022387121455 0.7218832199817727 1.0084372228556087 1.0114474679416423 0.9796113990480854 0.9145181067502733 1.084386405480217 0.9521510863912269 1.1229673059169218 1.040278457896075 1.0 15.70568698378102 -4.761407820157403 7.538638438592302 1.0129946420566978 0.7172494917038401 0.6999807635235747 0.05711430843008142 0.05628122866160604 23.19748292872956 0.014299201143819797 0.08496370670939958 1.7321766495742978e-05 4.761407820157403 -0.29574515035285764 S(ph)VEDLVR ddPTM_PC-9_AZD4547_30min_R2 2 SVEDLVR 7 0 Q7L9B9 Q7L9B9 EEPD1 Endonuclease/exonuclease/phosphatase family domain-containing protein 1 1 S(1)VEDLVR;S(1)VEDLVR 134.77 0.0039603 13636600.0 25458.0 44466.0 44553.0 40461.0 42416.0 28314.0 35905.0 52269.0 37904.0 26935.0 True False 33553.11444070453 58838.76491997702 43962.198109586956 31133.341566218496 36527.270553454415 26543.521104038584 39100.47544279848 44192.02707213053 39907.52805745031 25992.01384837593 1.2909009142745222 2.2637247449625173 1.691373295122104 1.1978041312163972 1.4053266809773097 1.0212183349424122 1.5043265085533806 1.7002155865999509 1.5353765310472036 1.0 14.665780796988223 -5.602799174107297 6.058734185948506 1.3656328558898314 1.8248930614900307 0.27451288071968016 0.30345762583765845 0.2441527237482761 14.320004002760273 0.08168586346184871 0.1434221894113046 2.495748540962676e-06 5.602799174107297 0.4592602056001993 S(ph)VEDLVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVEDLVR 7 0 Q7L9B9 Q7L9B9 EEPD1 Endonuclease/exonuclease/phosphatase family domain-containing protein 1 1 S(1)VEDLVR;S(1)VEDLVR 113.18 0.0090613 10572600.0 24688.0 24292.7 27672.0 18143.9 42581.0 18627.9 20903.8 19462.9 18004.3 19945.9 True False 28867.19078977351 26704.31871113876 28331.80542664439 17127.356106317464 34237.5587202661 17651.02013145621 18923.640733593842 18952.019497647147 18267.57882671079 23561.93377834248 1.2251622070302006 1.1333670216697016 1.2024397357693217 0.7269079128836397 1.4530878085964394 0.7491329148747787 0.8031446362432256 0.8043490689659502 0.7753004909767582 1.0 14.524170328647244 -6.803321466388573 24.999901928608942 0.8127044160831488 1.1269791766159507 0.4422778975234972 0.17957187810536565 136.7358851622497 81618.29906972307 0.06031529936544757 0.05319354011102105 1.5728182275912594e-07 6.803321466388573 0.3142747605328019 S(ph)VEDLVR ddPTM_PC-9_Lapatinib_30min_R1 3 SVEDLVR 7 0 Q7L9B9 Q7L9B9 EEPD1 Endonuclease/exonuclease/phosphatase family domain-containing protein 1 1 S(1)VEDLVR;S(1)VEDLVR;S(1)VEDLVR 112.11 0.0092188 12209100.0 113819.0 122785.0 49893.6 31934.0 51440.2 34473.299999999996 29116.8 28763.699999999997 67072.0 20408.2 True False 112195.92018815156 122500.69887638785 45791.5408028656 34282.53288870114 48414.58857132437 32998.95732018729 30624.32543440344 30100.166509049417 59517.64506052834 23935.730177782836 4.687382392549357 5.11790106115472 1.9131039856627958 1.4322743711625818 2.0226911070489435 1.3786484504582588 1.2794397834091964 1.2575411857286232 2.486560661340203 1.0 14.546878196795696 -5.294917821373118 5.189827642800602 1.578219938050261 4.923478684334686 0.9084708163979252 0.42033870333259216 0.043628934890199984 3.2491522410443863 0.10696755776337549 0.24253971460335816 5.070866517971607e-06 5.294917821373118 3.3452587462844248 S(ph)VEDVRPHHTDANNQSACFEAPDQK ddPTM_PC-9_AZD4547_30min_R2 2 SVEDVRPHHTDANNQSACFEAPDQK 25 1 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3 E7EPN9 PRRC2C Protein PRRC2C 1 S(0.911)VEDVRPHHT(0.085)DANNQS(0.004)ACFEAPDQK;S(0.984)VEDVRPHHT(0.012)DANNQS(0.003)ACFEAPDQK 49.577 0.01174 51226000.0 47758.0 45314.0 156527.0 262572.0 233050.0 196039.0 143668.0 228503.0 161725.0 223217.0 True False 62944.050571889675 59960.864336433195 154451.34970707502 202040.08209696077 200695.0302358201 183780.65033957124 156454.17367820514 193193.1118265714 170273.45333186857 215402.2407719667 0.29221632210653153 0.27836694790891303 0.7170368755382787 0.9379664824882131 0.931722109837677 0.8531974861585989 0.7263349402378488 0.8968946243743734 0.790490631488494 1.0 17.716673732368093 -5.35166071392083 3.2167182771855876 0.8661450059164005 0.2734278041158827 0.9055835147503651 0.07512785883332958 0.06705960083333835 1.3157889813191512 0.02065060755747613 0.051418236299178 4.449787647285035e-06 5.35166071392083 -0.5927172018005178 down S(ph)VEDVRPHHTDANNQSACFEAPDQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SVEDVRPHHTDANNQSACFEAPDQK 25 1 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3 E7EPN9 PRRC2C Protein PRRC2C 1 S(0.774)VEDVRPHHT(0.203)DANNQS(0.023)ACFEAPDQK;S(0.809)VEDVRPHHT(0.152)DANNQS(0.039)ACFEAPDQK;S(0.75)VEDVRPHHT(0.245)DANNQS(0.005)ACFEAPDQK 50.413000000000004 0.010138 30137200.0 28479.1 39385.3 84994.0 113333.0 121762.0 125624.0 116242.0 105717.0 107113.0 78838.0 True False 33300.04914213542 43295.21229562021 87020.57930153984 106983.31944054371 97903.6101758307 119036.05629158695 105230.716240799 102942.04076642057 108679.324987113 93130.70531873517 0.35756251419086404 0.4648865500099512 0.9343919280297113 1.1487437905081752 1.0512495297953612 1.2781612238862792 1.12992504331039 1.105350167961325 1.1669548149041011 1.0 16.506969284257714 -5.313543989490952 2.1921032109039738 1.1350734717168085 0.34886638887687227 0.9420038767477239 0.07013699107947798 0.06601740068356837 0.5928113493136452 0.019052322134981585 0.06372274475133395 4.8579832215381225e-06 5.313543989490952 -0.7862070828399362 down S(ph)VEDVRPHHTDANNQSACFEAPDQK ddPTM_PC-9_Lapatinib_30min_R1 1 SVEDVRPHHTDANNQSACFEAPDQK 25 1 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3 E7EPN9 PRRC2C Protein PRRC2C 1 S(0.973)VEDVRPHHT(0.02)DANNQS(0.007)ACFEAPDQK 50.891000000000005 0.0092225 26436000.0 76325.0 60026.0 126540.0 69068.0 94305.0 125110.0 86607.0 93320.0 150830.0 78376.0 True False 75236.59150370931 59887.01348498646 116136.36965852563 74147.49112409363 88758.1653107635 119759.33694565452 91091.08668869433 97655.98788140912 133841.93708968718 91923.18717054467 0.8184723987444343 0.6514897419067766 1.2634066902299455 0.8066244590336944 0.9655688411465857 1.3028196762092852 0.9909478717235234 1.062365121220486 1.456019326672941 1.0 16.488141199676917 -4.7804179172632155 0.4558207878055203 1.168394951092017 0.43238158457091047 0.31018639150783966 0.19582408953443955 6.118964625177427 0.9878653122463442 0.1380624229782289 2.4567958856853678 1.657990671596307e-05 4.7804179172632155 -0.7360133665211066 S(ph)VEEELHQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVEEELHQR 9 0 F5H5A3;Q8IVH8-3;Q8IVH8-2;Q8IVH8 F5H5A3 MAP4K3 Mitogen-activated protein kinase kinase kinase kinase;Mitogen-activated protein kinase kinase kinase kinase 3 1 S(1)VEEELHQR 120.96 0.0001125 0.0 13366.0 14654.0 14724.0 14884.0 19059.0 13560.0 20790.0 15112.0 16963.0 15243.0 True False 15628.59980946666 16108.752275087878 15075.076001080957 14050.097734579076 15324.525766176275 12848.889728984273 18820.6206934345 14715.32601248753 17211.051784156858 18006.435236478395 0.8679452431431519 0.8946108468184703 0.8372049105278243 0.7802820241796466 0.8510582780500071 0.7135720957668683 1.0452163599437319 0.8172259427938541 0.9558278225603363 1.0 14.136224976357667 -8.188296031251507 0.816577875812498 0.9948407392210995 0.8361599184883458 0.29854084029754613 0.08029797881918714 0.7652813545713115 1.0743452534467113 0.07457767672196965 0.029001158083784066 6.481924508766672e-09 8.188296031251507 -0.1586808207327537 S(ph)VEEELHQR ddPTM_PC-9_Lapatinib_30min_R1 1 SVEEELHQR 9 0 F5H5A3;Q8IVH8-3;Q8IVH8-2;Q8IVH8 F5H5A3 MAP4K3 Mitogen-activated protein kinase kinase kinase kinase;Mitogen-activated protein kinase kinase kinase kinase 3 1 S(1)VEEELHQR 134.38 0.00063381 3410200.0 19027.0 20658.0 22875.0 18481.0 24047.0 23721.0 21790.0 20402.0 27580.0 17644.0 True False 18755.67149087553 20610.167670223746 20994.30580005353 19840.15439080871 22632.602738221016 22706.508126351775 22918.17958071116 21349.95140116278 24473.649969724655 20693.741890847818 0.9063450964936683 0.9959613770643851 1.0145243866861335 0.9587514184461429 1.093693100919109 1.0972644892412686 1.107493255767684 1.031710529384982 1.182659477382801 1.0 14.336906919830211 -6.264612064498572 24.87530771290289 1.088746545706861 0.9740880402946197 0.5427234817104274 0.052282902463283355 197.53710128285158 1548779.7014326074 0.015168068102591598 0.017925601248986643 5.4373580909234e-07 6.264612064498572 -0.11465850541224132 S(ph)VEEPTQPGGTGLSDSR ddPTM_PC-9_AZD4547_30min_R2 2 SVEEPTQPGGTGLSDSR 17 0 Q9H0B6;Q9H0B6-2 Q9H0B6 KLC2 Kinesin light chain 2 1 S(1)VEEPTQPGGTGLSDSR;S(1)VEEPTQPGGTGLSDSR 227.41 4.2657999999999997e-29 10342100.0 17012.4 14774.599999999999 16411.7 11592.0 14169.300000000001 19630.6 19080.8 20265.5 14648.2 16373.099999999999 True False 22421.989320097502 19550.200516949848 16194.070134785712 8919.643494614693 12202.137274921286 18403.095478736297 20778.9542355925 17133.932629862098 15422.473947107002 15799.882752583782 1.4191237790312587 1.2373636452303907 1.0249487536315716 0.5645385876775604 0.7722929002701523 1.1647615217731162 1.3151334450373995 1.0844341630991 0.9761131894845826 1.0 13.947626232072489 S(ph)VEEPTQPGGTGLSDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SVEEPTQPGGTGLSDSR 17 0 Q9H0B6;Q9H0B6-2 Q9H0B6 KLC2 Kinesin light chain 2 1 S(0.996)VEEPT(0.004)QPGGTGLSDSR;S(1)VEEPTQPGGTGLSDSR;S(0.986)VEEPT(0.014)QPGGTGLSDSR 169.06 1.016e-07 6621100.0 13537.2 19296.800000000003 19971.1 18835.9 22146.3 18467.3 20525.7 12164.5 13177.1 11821.0 True False 15828.780588112533 21212.458775891606 20447.28676481851 17780.58558981173 17806.891493544765 17498.842278176362 18581.35710280079 11845.194764353133 13369.790158875978 13964.053725015483 1.1335376460029327 1.5190759928036646 1.4642801558539433 1.2733111702341302 1.2751950002630787 1.2531348434178957 1.330656374481987 0.8482633336717558 0.9574433343037825 1.0 13.769430192158906 -7.754736078255713 24.989310636800692 0.9271399760327557 1.328175848460695 0.7280011645445754 0.1080528285744947 76.37144449012926 284708.9673331388 0.053725736519795494 0.030108962371770076 1.7589922328047743e-08 7.754736078255713 0.40103587242793926 S(ph)VEEPTQPGGTGLSDSR ddPTM_PC-9_Lapatinib_30min_R1 2 SVEEPTQPGGTGLSDSR 17 0 Q9H0B6;Q9H0B6-2 Q9H0B6 KLC2 Kinesin light chain 2 1 S(1)VEEPTQPGGTGLSDSR;S(1)VEEPTQPGGTGLSDSR 273.77 1.5606999999999997e-82 10584900.0 14007.599999999999 19301.8 21644.0 18903.9 20589.4 17974.4 13888.7 16353.8 19119.1 29160.0 True False 13807.849055320768 19257.107867999057 19864.51386825612 20294.155867561756 19378.37197231786 17205.676812372883 14607.788928068987 17113.6572504821 16965.705624951515 34200.26714674237 0.40373512277186957 0.5630689311686656 0.5808292018019586 0.5933917352307818 0.5666146375164698 0.503086035513958 0.4271249948250887 0.500395426066495 0.4960693889365576 1.0 15.061719973952293 -11.06543699264177 2.6954781412350655 1.0281373393522548 0.5187487416177189 0.8532459579431243 0.060332866412299124 6803134.769486521 6748231.224101475 1388223.370258678 0.017040957640930124 8.601278450162503e-12 11.06543699264177 -0.5093885977345359 S(ph)VELCCASR ddPTM_PC-9_AZD4547_30min_R2 3 SVELCCASR 9 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 S(1)VELCCASR;S(1)VELCCASR;S(1)VELCCASR 108.31 0.0024439 27202000.0 6018.1 10584.5 13645.900000000001 20688.7 22814.699999999997 12680.9 6749.8 21452.7 14474.4 9122.8 True False 7931.730615743734 14005.732633821275 13464.946449927334 15919.239852228693 19647.272715387975 11887.961318365577 7350.5191239047745 18137.6781490041 15239.487233926733 8803.413548764205 0.9009835300600146 1.5909433944276485 1.5295142475520191 1.8083030819861217 2.2317789124135827 1.3503808781122602 0.8349623794438938 2.060300592325372 1.7310884180905035 1.0 13.103847326021722 -4.761240718701592 7.445406424306943 1.601582972233308 0.8892044599449774 0.1900562579975017 0.4104850945549953 0.17369252997274953 67.00946655501546 0.10417170132107904 0.623020812685827 1.7328432593151195e-05 4.761240718701592 -0.7123785122883305 S(ph)VELCCASR ddPTM_PC-9_Lapatinib_30min_R1 2 SVELCCASR 9 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 S(1)VELCCASR;S(1)VELCCASR 82.494 0.015693000000000002 13776600.0 10917.9 12156.1 11291.5 6260.4 9605.5 10799.5 8501.4 7327.099999999999 9915.8 9829.1 True False 10762.208743902354 12127.953297318561 10363.156456450464 6720.810700082188 9040.523375139597 10337.630559864085 8941.560894330323 7667.543814893632 8798.978185996944 11528.046838547501 0.9335674025816466 1.0520388637531461 0.898951626549445 0.5829964775654043 0.7842198684437923 0.8967373835867061 0.7756353716773181 0.6651208068703266 0.7632670398748648 1.0 13.49286048186827 -5.529292081661327 24.960895929547846 0.7695227671925723 0.9884761927075054 0.37439807062648134 0.1106086934808494 140.27270732725535 545943.8251755837 0.029429593826521667 0.05113837853698019 2.956023745155426e-06 5.529292081661327 0.21895342551493313 S(ph)VELDLNQAHMEETPK ddPTM_PC-9_AZD4547_30min_R2 2 SVELDLNQAHMEETPK 16 0 Q14680-3;Q14680-4;Q14680-5;Q14680-2;Q14680-8;Q14680-6;Q14680;Q14680-7 Q14680-3 MELK Maternal embryonic leucine zipper kinase 1 S(1)VELDLNQAHMEETPK;S(1)VELDLNQAHMEETPK 130.02 8.6737e-06 2854100.0 24594.0 27787.0 29702.0 39652.0 40247.0 34122.0 33634.0 35315.0 31010.0 36749.0 True False 32414.380413020965 36768.60434559889 29308.132073057972 30510.844017293108 34659.398763789104 31988.345945892648 36627.36084230839 29857.878207968202 32649.125291830285 35462.42869552505 0.9140485185412945 1.0368326620065553 0.8264558619121403 0.8603709655436889 0.9773554727841504 0.9020348329929588 1.0328497564784767 0.8419580752441788 0.9206680561038457 1.0 15.114003724218183 -6.282652331808339 24.97357634149325 0.9400720565297092 0.9126008813128392 0.05487418926556331 0.07115010459130336 3636.27862482909 4280908.176760369 0.022514418249074308 0.02556170399043611 5.216121130737441e-07 6.282652331808339 -0.027471175216869925 S(ph)VELDLNQAHMEETPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVELDLNQAHMEETPK 16 0 Q14680-3;Q14680-4;Q14680-5;Q14680-2;Q14680-8;Q14680-6;Q14680;Q14680-7 Q14680-3 MELK Maternal embryonic leucine zipper kinase 1 S(1)VELDLNQAHMEETPK 67.866 0.016802 9629600.0 49592.0 65858.0 53837.0 67797.0 69204.0 81670.0 69158.0 58481.0 66633.0 59845.0 True False 57986.9461133526 72395.94699964089 55120.67825795946 63998.55389083959 55643.97298507076 77387.08142818177 62606.85357943929 56945.9357157414 67607.3815677488 70694.42476724065 0.82024779612074 1.0240686905368062 0.7797033279419515 0.9052843148742349 0.7871055343936517 1.09467021880405 0.8855981753238752 0.8055223011324336 0.9563325791297426 1.0 16.10930882262075 S(ph)VELDLNQAHMEETPK ddPTM_PC-9_Lapatinib_30min_R1 3 SVELDLNQAHMEETPK 16 0 Q14680-3;Q14680-4;Q14680-5;Q14680-2;Q14680-8;Q14680-6;Q14680;Q14680-7 Q14680-3 MELK Maternal embryonic leucine zipper kinase 1 S(1)VELDLNQAHMEETPK;S(1)VELDLNQAHMEETPK;S(1)VELDLNQAHMEETPK 164.5 7.648099999999999e-06 18987600.0 162909.0 149784.0 154601.0 132214.0 167940.0 147267.0 143242.0 144037.0 154036.0 136924.0 True False 160585.88778614844 149437.18435070137 141890.3025571178 141937.45861297482 158062.09938274365 140968.7337061441 150658.36987151104 150729.48485292084 136686.84360901028 160591.1309602387 0.999967350786691 0.9305444420072054 0.8835500547801043 0.8838436952543637 0.9842517356819586 0.8778114511258223 0.9381487568501716 0.9385915894087605 0.8511481474207504 1.0 17.29303269311395 S(ph)VENLPECGITHEQR ddPTM_PC-9_AZD4547_30min_R2 4 SVENLPECGITHEQR 15 0 Q9UBF8-2;A0A0B4J1S8;Q9UBF8;F8W860;Q9UBF8-3 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 S(1)VENLPECGITHEQR;S(1)VENLPECGITHEQR;S(1)VENLPECGITHEQR;S(1)VENLPECGITHEQR 175.52 3.4354000000000003e-05 224104000.0 191830.0 201869.0 293502.0 375945.0 314231.0 283431.0 307992.0 346098.0 252633.0 279060.0 True False 252827.9496881282 267119.20648654766 289609.97170920024 289276.68854235 270605.4496718816 265708.01476438384 335402.6913404371 292616.50664084294 265986.6646195086 269290.19433925336 0.9388680130313771 0.9919381102678745 1.0754568038387164 1.0742191681064983 1.00488415605275 0.9866976976875859 1.2455065144997253 1.0866214692994092 0.9877324544703513 1.0 18.038802172394895 S(ph)VENLPECGITHEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SVENLPECGITHEQR 15 0 Q9UBF8-2;A0A0B4J1S8;Q9UBF8;F8W860;Q9UBF8-3 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 S(1)VENLPECGITHEQR;S(1)VENLPECGITHEQR;S(1)VENLPECGITHEQR;S(1)VENLPECGITHEQR;S(1)VENLPECGITHEQR 128.45 2.3373e-05 195178000.0 162441.4 160524.2 201395.4 216681.0 218115.1 202049.7 204897.5 184062.4 188287.4 160841.3 True False 189939.520656105 176459.98170852102 206197.4301323074 204541.0660592804 175377.01190734658 191453.85804383128 185488.12547056229 179230.95703023297 191040.74702023584 190000.55447096983 0.9996787703328827 0.9287340355392611 1.0852464652349858 1.0765287850280048 0.923034211114065 1.007648943851285 0.976250442989644 0.9433180736197149 1.0054746816511262 1.0 17.53564410315804 -6.264893782206234 24.994860863228425 0.9747198285826776 1.02032461772437 0.18705247886850784 0.04745306534570988 585.1636469925453 4234027.528098253 0.015228430566883881 0.01796318604147634 5.433832134676967e-07 6.264893782206234 0.045604789141692526 S(ph)VENLPECGITHEQR ddPTM_PC-9_Lapatinib_30min_R1 5 SVENLPECGITHEQR 15 0 Q9UBF8-2;A0A0B4J1S8;Q9UBF8;F8W860;Q9UBF8-3 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 S(1)VENLPECGITHEQR;S(1)VENLPECGITHEQR;S(1)VENLPECGITHEQR;S(1)VENLPECGITHEQR;S(1)VENLPECGITHEQR 223.82 1.8532e-24 212143000.0 365336.2 340317.4 376550.5 331655.3 376588.9 351942.7 294274.6 326076.5 360727.4 255491.4 True False 360126.43879354623 339529.415969338 345591.971416964 356046.33713164786 354438.6813042638 336890.93113950425 309510.6988913235 341227.2045907873 320098.4815840774 299652.7480691094 1.2018125684283385 1.1330762629649962 1.1533081997207635 1.1881964688324245 1.1828314059796945 1.124271121524327 1.0328979156231217 1.138742116631914 1.0682314233615924 1.0 18.192932079139403 -7.985248931925998 0.3963079892138418 0.9972792961962395 1.1836226777102146 0.684763452416046 0.0361929787680447 0.7002434813805964 0.3183186998256228 0.04904796576280662 0.037498686852245666 1.0345490067183292e-08 7.985248931925998 0.18634338151397511 S(ph)VEPQDAGPLER ddPTM_PC-9_AZD4547_30min_R2 2 SVEPQDAGPLER 12 0 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 S(1)VEPQDAGPLER;S(1)VEPQDAGPLER 127.66 0.00022751 13804000.0 25613.0 30104.7 34637.0 48846.0 41137.0 37483.0 34396.0 38739.0 28298.8 34298.0 True False 33757.40121650426 39835.45554550515 34177.69074858623 37585.3093631771 35425.83762630736 35139.18208457575 37457.17736611881 32752.777683660785 29794.616794854766 33097.237459498705 1.019946189098513 1.2035885349722026 1.032644817876709 1.1356026136371797 1.0703563301818824 1.0616953190602625 1.1317312332171345 0.9895924916313805 0.900214612513042 1.0 15.014423183596847 -7.901964659261204 4.885836948526807 0.9483939579923264 1.0946492926892004 0.5394274149795508 0.05585281056767612 0.14054898323994997 5.502627657805327 0.029720959227154363 0.013680407577043186 1.2532431535268185e-08 7.901964659261204 0.14625533469687402 S(ph)VEPQDAGPLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVEPQDAGPLER 12 0 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 S(1)VEPQDAGPLER;S(1)VEPQDAGPLER 150.12 7.9571e-05 14267200.0 65367.0 69140.0 65574.0 67772.0 78914.0 62103.0 79054.0 64546.0 61046.0 56243.0 True False 76432.34204290037 76003.76226965849 67137.53285077977 63974.95455978848 63451.368188888904 58846.20935391668 71565.43281860379 62851.73589214007 61938.682262314396 66439.41068065696 1.1504066827184054 1.143955996764825 1.0105076514522133 0.9629067131146908 0.9550260536456264 0.8857123919530648 1.077153335428955 0.9460008035627956 0.9322581526200548 1.0 16.019751656163038 -5.340533577464983 2.7100305353272045 0.9645247190993069 1.154725413718709 0.7018382064002568 0.04664264725579661 0.14842882267069388 2.091099320130343 0.012846937027048304 0.03551525451268398 4.565269524699464e-06 5.340533577464983 0.19020069461940214 S(ph)VEPQDAGPLER ddPTM_PC-9_Lapatinib_30min_R1 2 SVEPQDAGPLER 12 0 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 S(1)VEPQDAGPLER;S(1)VEPQDAGPLER 155.06 0.00018484 15471400.0 43874.0 29675.0 40881.0 36545.0 36870.0 39449.0 28356.0 27180.0 38213.0 26425.0 True False 43248.34871449379 29606.28936072656 37519.92198522354 39232.641210546215 34701.37908920898 37761.8582301105 29824.13493302643 28442.88202546832 33909.04953927077 30992.52604090078 1.3954444583645433 0.9552719039956664 1.210611937075041 1.2658742678402841 1.11966927263088 1.2184182141293112 0.9623008751744719 0.9177335847982285 1.094104091241903 1.0 14.9196327258954 -7.263215988907965 24.980561325205066 0.9866790950230856 1.1839680730096016 0.43040465834698705 0.1126184849565375 153.84965891588394 2163229.3987500295 0.0435464553145426 0.03110526231948434 5.4548650526708256e-08 7.263215988907965 0.197288977986516 S(ph)VFGTPTLETANK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVFGTPTLETANK 13 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 S(0.995)VFGT(0.005)PTLETANK 195.71 1.0981000000000001e-06 13870000.0 74375.0 76386.0 71480.0 76414.0 75758.0 61865.0 73913.0 44656.0 51407.0 45827.0 True False 86965.2185267904 83969.09726251259 73184.35428940973 72132.77131753058 60913.76373335336 58620.690492891765 66911.42555622052 43483.82731694305 52158.73012251084 54135.072333667624 1.6064487360572914 1.551103446301126 1.3518842985621171 1.332459128768354 1.1252181092121667 1.0828597426004445 1.236008795625217 0.8032468682950228 0.963492388095921 1.0 15.724275951193086 -5.617228613488577 0.4629620862260507 0.9294683566476085 1.8271939815007523 0.8493850006253574 0.09528181102237117 0.8680548757685154 0.2508118273934161 0.07652370729235326 0.39615779254791533 2.4141896656068163e-06 5.617228613488577 0.8977256248531438 S(ph)VGDGETVEFDVVEGEK ddPTM_PC-9_AZD4547_30min_R2 1 SVGDGETVEFDVVEGEK 17 0 H0Y449;P67809;Q9Y2T7;P16989-2;P16989;P16989-3;A0A0D9SEI8 H0Y449;P16989-2 YBX1;YBX2;YBX3 Nuclease-sensitive element-binding protein 1;Y-box-binding protein 2;Y-box-binding protein 3 1 S(1)VGDGETVEFDVVEGEK 206.63 1.2635999999999997e-66 0.0 5267.0 4448.8 7516.0 6524.9 5843.0 7239.6 6088.0 6983.0 6771.2 6113.7 True False 6941.79643959427 5886.787598974358 7416.332929132836 5020.685113700088 5031.800307521549 6786.906667542478 6629.820205981257 5903.937803376528 7129.11180832122 5899.6612238654525 1.1766432302100918 0.9978179043842351 1.257077762216601 0.8510124434586669 0.8528964827957898 1.1503892189754759 1.1237628661052854 1.0007248856076305 1.2083934208768403 1.0 12.526416397665079 -10.167248835215034 15.312425496625211 0.9999999997605127 1.0614657708069275 0.020499962661808202 0.13432728588714646 0.0 0.0 0.13108313855897988 0.03179233094212643 6.803794139070003e-11 10.167248835215034 0.06146577104641482 S(ph)VGDGETVEFDVVEGEK ddPTM_PC-9_Lapatinib_30min_R1 1 SVGDGETVEFDVVEGEK 17 0 H0Y449;P67809;Q9Y2T7;P16989-2;P16989;P16989-3;A0A0D9SEI8 H0Y449;P16989-2 YBX1;YBX2;YBX3 Nuclease-sensitive element-binding protein 1;Y-box-binding protein 2;Y-box-binding protein 3 1 S(0.832)VGDGET(0.168)VEFDVVEGEK 99.344 0.0094891 0.0 1986.9 2156.7 2637.6 2060.9 2258.1 3093.4 3386.1 2245.0 3989.5 2373.0 True False 1958.566441647165 2151.706293657253 2420.7467094304334 2212.465460960862 2125.282997595412 2961.102493067601 3561.4156896854547 2349.3108957754366 3540.160498702556 2783.169888176255 0.7037178901538659 0.7731135288572754 0.8697804326334858 0.7949444517778388 0.7636195715627189 1.063931636242278 1.2796256904098533 0.8441133635988295 1.2719886463784427 1.0 11.44251325993194 -6.791092447636894 6.242916278657337 1.0960799059853563 0.7859105376919485 0.6132410574395712 0.12349896147541298 0.11815963616079403 13.890444930391137 0.04118392534961024 0.03717133875705695 1.6177356359481531e-07 6.791092447636894 -0.3101693682934078 S(ph)VGGSGGGSFGDNLVTR ddPTM_PC-9_AZD4547_30min_R2 1 SVGGSGGGSFGDNLVTR 17 0 P02545;P02545-3;P02545-5;P02545-4;A0A0C4DGC5 P02545 LMNA Prelamin-A/C;Lamin-A/C 1 S(0.957)VGGS(0.043)GGGSFGDNLVTR 92.8 0.0019846 21503000.0 6078.1 6325.2 8251.3 13001.0 12177.0 9737.4 8902.3 11498.0 9685.7 9145.0 True False 8010.809367666209 8369.697203972439 8141.882370696357 10003.820313447686 10486.433740320033 9128.51883868281 9694.587453959752 9721.248297755023 10197.666328251551 8824.836333521365 0.9077572733260725 0.9484252044629917 0.9226100137142724 1.133598396091259 1.1882864841908793 1.0344122535177112 1.098557195574791 1.101578310390711 1.1555643575524972 1.0 13.107353806897844 -5.757296944732365 24.966023709882677 1.1066177254140854 0.9284802187056475 0.7022826148652688 0.052274818496594544 54.24744065421219 326938.0532954082 0.014097374896726746 0.023337690163723664 1.7486506564844379e-06 5.757296944732365 -0.17813750670843798 S(ph)VGGSGGGSFGDNLVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVGGSGGGSFGDNLVTR 17 0 P02545;P02545-3;P02545-5;P02545-4;A0A0C4DGC5 P02545 LMNA Prelamin-A/C;Lamin-A/C 1 S(0.93)VGGS(0.033)GGGS(0.037)FGDNLVTR;S(0.499)VGGS(0.052)GGGS(0.45)FGDNLVTR 112.57 0.00025125 32248200.0 21709.4 22559.9 23842.1 33548.8 30973.4 28359.6 36541.7 30005.9 28543.1 29018.0 True False 25384.372639805148 24799.497778814984 24410.586085667772 31669.169502677123 24904.38461441231 26872.37265177747 33080.2056370022 29218.27691887901 28960.488839260008 34278.733693638394 0.74052830733698 0.7234659833253231 0.712120415644117 0.9238722114333656 0.7265258056785855 0.7839371457518155 0.9650358129519053 0.8523732871818854 0.8448529370451812 1.0 15.06502619472764 -2.1145992091456796 0.06920645978456522 1.2136641285764074 3.770134154039386e-08 0.5441685844432329 0.06841146122082874 180.47842287757967 1.0355098513871959 3.5234019759682123 21.785989449929847 0.007680699796514542 2.1145992091456796 -1.2136640908750658 S(ph)VGGSGGGSFGDNLVTR ddPTM_PC-9_Lapatinib_30min_R1 1 SVGGSGGGSFGDNLVTR 17 0 P02545;P02545-3;P02545-5;P02545-4;A0A0C4DGC5 P02545 LMNA Prelamin-A/C;Lamin-A/C 1 S(0.96)VGGS(0.04)GGGSFGDNLVTR 84.65299999999999 0.023698 0.0 10423.0 8291.0 10561.0 7228.5 8660.5 7411.9 9800.4 9176.1 9112.4 8288.8 True False 10274.366108655897 8271.802698897518 9692.715346638917 7760.108003569114 8151.106417198117 7094.910314982785 10307.81675827451 9602.455104999986 8086.065554174 9721.508035868243 1.0568695793644198 0.8508764965659724 0.9970382486829109 0.7982411756424627 0.8384611098529149 0.7298158154892815 1.060310470375896 0.9877536560758885 0.8317707010414276 1.0 13.246964411982194 -9.54157939214115 11.468013975054438 1.00000068013256 0.9034090803517311 0.06351934576858909 0.10832981028949443 0.0 0.0 0.10572060903062297 0.025641013990463937 2.873562237843253e-10 9.54157939214115 -0.09659159978082899 S(ph)VHREESCSDSGTK ddPTM_PC-9_AZD4547_30min_R2 1 SVHREESCSDSGTK 14 1 Q5T5Y3-2;Q5T5Y3;Q5T5Y3-3 Q5T5Y3-2 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1 1 S(1)VHREESCSDSGTK 72.433 0.029845999999999998 0.0 6249.6 6724.7 6585.6 11542.0 9887.0 10956.0 6619.1 6942.4 10015.0 10115.0 True False 8236.842800244602 8898.327766324139 6498.270641045398 8881.17022212239 8514.360712042713 10270.919588042896 7208.187077104224 5869.611600481342 10544.372453972279 9760.876928766385 0.8438629910361551 0.9116320010243938 0.6657466013011879 0.9098742138576297 0.8722946487471785 1.0522537742252809 0.738477406252393 0.6013406011895249 1.0802689687539082 1.0 13.25279505170741 -8.314155613116988 24.999963036235997 1.0401348673990232 0.8312238457774948 0.32278966484139127 0.12466143071765466 482.4896196164683 228809.85709425953 0.1231016391672839 0.0317847957443986 4.851146464026923e-09 8.314155613116988 -0.20891102162152841 S(ph)VHREESCSDSGTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVHREESCSDSGTK 14 1 Q5T5Y3-2;Q5T5Y3;Q5T5Y3-3 Q5T5Y3-2 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1 1 S(1)VHREESCSDSGTK 56.25 0.033788 3578600.0 7718.6 6212.1 9551.2 12675.0 9195.7 9378.5 11980.0 7078.2 8564.3 6184.3 True False 9025.206530700983 6828.796233661344 9778.936831127709 11964.860842904438 7393.868596884789 8886.674950094328 10845.16767231098 6892.404749972826 8689.536685436222 7305.46463510814 1.235404862180595 0.9347518022117233 1.3385783546378025 1.637796011687534 1.0121010731270674 1.2164421284564582 1.484528118881304 0.9434587797263083 1.1894570871887595 1.0 12.834760317505939 -7.7841488965009535 24.999965913113513 1.0498434790328937 1.2584030364329766 0.20286466756588029 0.20062360746732724 443.51305606371426 488238.0716441476 0.11267746243672881 0.054187839354862266 1.6438080521591564e-08 7.7841488965009535 0.20855955740008292 S(ph)VIDPVPAPVGDSHVDGAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVIDPVPAPVGDSHVDGAAK 20 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 S(1)VIDPVPAPVGDSHVDGAAK;S(1)VIDPVPAPVGDSHVDGAAK 165.0 2.8609e-08 10237800.0 74081.0 91644.0 80175.0 85280.0 102347.0 95252.0 78338.0 90703.0 73582.0 73921.0 True False 86621.45013355512 100741.81066590376 82086.67606538058 80502.03808149029 82292.8400540868 90256.81743843727 70917.25752199496 88322.14235777238 74657.99754653237 87322.29214168598 0.991974076825724 1.153678037933816 0.940042617435989 0.9218956134462276 0.9424035722809638 1.033605683322992 0.8121323408108344 1.0114501141869259 0.854970657726151 1.0 16.41406237998857 -5.288651650723045 22.837634538329535 0.9382495667829609 1.0728260111610313 0.3427239266785863 0.07380187531017847 219.18792221290195 183951.0981385949 0.01784938490523106 0.03718121376314824 5.144561333801008e-06 5.288651650723045 0.13457644437807037 S(ph)VIDPVPAPVGDSHVDGAAK ddPTM_PC-9_Lapatinib_30min_R1 1 SVIDPVPAPVGDSHVDGAAK 20 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 S(1)VIDPVPAPVGDSHVDGAAK 174.99 1.5872e-09 5847700.0 59576.0 47791.0 59019.0 60380.0 56639.0 51728.0 46705.0 40266.0 62361.0 46393.0 True False 58726.43531509968 47680.34287577027 54166.68563992824 64820.54662177534 53307.6053765584 49515.71402385753 49123.156370679884 42136.905358260025 55337.247489557645 54411.96823521326 1.0792926118980983 0.8762841048068071 0.9954921205161206 1.1912920764337664 0.9797036774358007 0.9100151240589186 0.902800577959783 0.7744050936755252 1.0170050686338816 1.0 15.731636395262473 -6.640448092054577 4.366400494229192 0.9058724451703352 1.0279699905264217 0.22968979529497657 0.09608553705278092 0.3153647129994178 10.525142703977062 0.033243888811446465 0.03306876952346704 2.2885052230063436e-07 6.640448092054577 0.12209754535608652 S(ph)VKEDSNLTLQEK ddPTM_PC-9_AZD4547_30min_R2 3 SVKEDSNLTLQEK 13 1 P46940;H0YLE8 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 1 S(1)VKEDSNLTLQEK;S(0.998)VKEDS(0.002)NLTLQEK;S(0.998)VKEDS(0.002)NLTLQEK 69.805 0.013997999999999998 31041900.0 119254.0 131857.0 148125.0 168778.0 162122.0 134954.0 120112.0 175289.0 142269.0 139134.0 True False 157174.29136270657 174477.19664582837 146160.76571684435 129868.83969410606 139614.15872942138 126515.30504606962 130801.73531222428 148202.11279050072 149789.0488920799 134262.9610090934 1.170645203870198 1.2995184623852543 1.0886156883352598 0.9672722746320952 1.0398560979149385 0.9422949121277087 0.9742205469709946 1.1038197852679805 1.1156393972417677 1.0 17.034701839228326 -5.4450261245221485 4.691754864728899 1.0205810324457802 1.2322249874541424 0.6626742774494138 0.060421096291702926 0.1295722026103508 5.140191025146676 0.016921623378017628 0.036057274222358784 3.5890034472755065e-06 5.4450261245221485 0.2116439550083622 S(ph)VKEDSNLTLQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SVKEDSNLTLQEK 13 1 P46940;H0YLE8 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 1 S(0.998)VKEDS(0.002)NLTLQEK;S(0.983)VKEDS(0.015)NLT(0.002)LQEK;S(1)VKEDSNLTLQEK;S(1)VKEDSNLTLQEK 119.56 0.0010913000000000001 28186900.0 174561.0 141488.6 138916.2 128600.9 169207.0 112617.4 117639.5 111389.8 93408.7 93889.0 True False 204110.72956309357 155534.653142418 142228.48905062204 121395.80850274305 136052.10301261285 106711.54529239773 106495.8349237753 108465.93577724863 94774.62552560102 110910.33247508516 1.8403220422131987 1.402345928206078 1.282373660565594 1.0945401189741573 1.2266855573909268 0.96214250657277 0.960197598791785 0.9779606043613146 0.8545157462844243 1.0 16.75903424855852 -1.5228787452889607 0.42577394766743426 0.9348430413084177 18.109164250613283 0.9279157482956267 0.07481077863201308 18.818796135764135 0.23849555350181703 0.04943136685762413 276.4218029460322 0.029999999999404333 1.5228787452889607 17.174321209304864 S(ph)VKEDSNLTLQEK ddPTM_PC-9_Lapatinib_30min_R1 1 SVKEDSNLTLQEK 13 1 P46940;H0YLE8 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 1 S(0.998)VKEDS(0.002)NLTLQEK 79.32600000000001 0.017528 0.0 33946.0 47712.0 36824.0 43558.0 30732.0 31194.0 25636.0 29139.0 32228.0 37628.0 True False 33461.92381506602 47601.525795416565 33796.47286475064 46761.40062522844 28924.404181436686 29859.905336765623 26963.306642088646 30492.90431714942 28598.143264114784 44131.9496638416 0.758224462548098 1.0786182382152418 0.7658051167506186 1.0595815725662627 0.6554073500436163 0.6766051707257924 0.610970211999955 0.6909484976172039 0.6480144992902036 1.0 15.429535863736755 -6.2796045585427835 24.765247098257486 0.691218040193452 0.9165079718261914 0.3219589173612373 0.14130230329417018 724.5877923000664 987854.308951398 0.04027489753999965 0.045760357760967305 5.252855347968687e-07 6.2796045585427835 0.22528993163273936 S(ph)VPARPR ddPTM_PC-9_Lapatinib_30min_R1 1 SVPARPR 7 1 M0R1W6 M0R1W6 HNRNPL 1 S(1)VPARPR 59.35 0.042234 0.0 1155.7 2551.1 2149.7 920.5 799.07 748.01 1143.4 929.32 905.87 1012.7 True False 1139.219506070577 2545.193084689116 1972.9599640819708 988.1966406979827 752.0702736320649 716.0193559964754 1202.5996573008322 972.4995998494555 803.8413813660068 1187.7438456620716 0.9591457873945486 2.1428804653333104 1.6610988735388517 0.8319947472740998 0.6331923136278986 0.6028398788270313 1.0125075888147244 0.8187789003506604 0.6767800854551512 1.0 10.214008016053393 -5.772439873570812 7.008023152121111 0.7811309210936197 1.6457592399872754 0.5948712437837469 0.29795741598132935 0.08495578582049966 20.37612377572868 0.08034274274221334 0.12641575356239515 1.6887296415379624e-06 5.772439873570812 0.8646283188936557 S(ph)VPEDDGHALLAER ddPTM_PC-9_Lapatinib_30min_R1 1 SVPEDDGHALLAER 14 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 S(1)VPEDDGHALLAER 65.905 0.021454 1657900.0 6352.6 8770.0 7981.0 7734.1 10046.0 7003.0 8283.3 7732.3 10999.0 6902.1 True False 6262.010759075841 8749.693603827196 7324.832987550921 8302.891514201272 9455.114031195915 6703.498014790335 8712.168743501828 8091.570886148954 9760.176795395266 8095.118788529847 0.7735539060833329 1.0808604336016454 0.9048456457402008 1.0256664208517636 1.168001888322266 0.8280913708503784 1.0762249413617369 0.9995617232466162 1.2056866675291629 1.0 12.982836535587152 -4.753923993322112 24.847067339574007 1.0271627920955781 0.7735534176580182 0.34642837428088535 0.10634367292287288 287.0341162997793 948895.0644450221 0.025376825429842598 0.25937184217296616 1.762284440073151e-05 4.753923993322112 -0.25360937443755993 S(ph)VPGTTLESFR ddPTM_PC-9_AZD4547_30min_R2 3 SVPGTTLESFR 11 0 Q8N1W1-5;Q8N1W1-4;Q8N1W1-3;Q8N1W1;Q8N1W1-6 Q8N1W1-5 ARHGEF28 Rho guanine nucleotide exchange factor 28 1 S(1)VPGTTLESFR;S(0.995)VPGT(0.004)T(0.001)LESFR;S(0.967)VPGT(0.014)T(0.019)LESFR 80.014 0.016638 13280000.0 11050.2 15435.4 17196.699999999997 26335.199999999997 26512.1 17136.4 18618.6 26300.5 22399.699999999997 23617.4 True False 14563.933741561535 20424.59119430154 16968.660521875827 20264.02651478406 22831.35254715765 16064.858199026861 20275.619330992537 22236.362050365795 23583.702412106122 22790.56201457708 0.6390335496003254 0.8961863766781074 0.7445476996584154 0.8891411498243429 1.0017897993280938 0.7048908310708446 0.8896498172368035 0.9756829180492866 1.034801265410732 1.0 14.476148881407852 -2.256160528930499 0.16958736494669974 1.041510859900025 5.892452112794463e-20 0.4509755379500706 0.09655461539488655 48.74895933084173 0.655831804718662 0.26761359518575634 12.25521031112166 0.005544207436951736 2.256160528930499 -1.041510859900025 S(ph)VPGTTLESFR ddPTM_PC-9_Lapatinib_30min_R1 1 SVPGTTLESFR 11 0 Q8N1W1-5;Q8N1W1-4;Q8N1W1-3;Q8N1W1;Q8N1W1-6 Q8N1W1-5 ARHGEF28 Rho guanine nucleotide exchange factor 28 1 S(0.994)VPGT(0.003)T(0.001)LES(0.001)FR 79.036 0.017726 2394000.0 2652.6 3926.6 5124.9 7287.8 5754.0 3540.5 2930.8 5314.5 6204.0 3861.0 True False 2614.773437572737 3917.508198949583 4703.550504686091 7823.769123388117 5415.561032799256 3389.0810683086056 3082.542483485463 5561.4310715361025 5505.240188983744 4528.368705540885 0.5774206138235423 0.8651036286325677 1.0386854098101277 1.7277235207934813 1.1959187479970013 0.7484110258428707 0.6807180872250271 1.2281312395634147 1.2157226027658845 1.0 12.14477571367985 -4.972613442607372 2.504390781665202 1.1086899625653996 0.56263769131111 0.27026377795796497 0.27313591561316847 0.5402770581525681 5.727114299035776 0.08066181228352061 0.5323242281064245 1.0650906136704919e-05 4.972613442607372 -0.5460522712542897 S(ph)VPGTTLESFRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVPGTTLESFRR 12 1 Q8N1W1-5;Q8N1W1-4;Q8N1W1-3;Q8N1W1;Q8N1W1-6 Q8N1W1-5 ARHGEF28 Rho guanine nucleotide exchange factor 28 1 S(0.999)VPGTTLESFRR 68.277 0.015997 1929200.0 13643.0 13067.0 13466.0 16374.0 19558.0 19094.0 17565.0 19925.0 16254.0 14448.0 True False 15952.490438467286 14364.205403205491 13787.080510089392 15456.61786522425 15725.750298277744 18092.67702693406 15901.116040412557 19401.98986228258 16491.68400045307 17067.308029694923 0.9346811114390157 0.8416210323393484 0.807806391382967 0.9056271696937632 0.9213960556003887 1.0600779569604724 0.9316710059223551 1.136792622979887 0.9662732969815545 1.0 14.058947904319655 -6.497010947742041 2.128205013948497 1.0229429852956604 0.8627251752175688 0.5566452740180816 0.06142169920987755 0.22149647022547386 2.0073867482844148 0.02135742975563905 0.023447439151127167 3.184117255143986e-07 6.497010947742041 -0.16021781007809166 S(ph)VPHLQK ddPTM_PC-9_Lapatinib_30min_R1 2 SVPHLQK 7 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YN28;H0YNP5;H0YL33 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 S(1)VPHLQK;S(1)VPHLQK 78.264 0.019925 0.0 41116.0 38593.0 34126.0 26396.0 41569.0 30143.0 31476.0 29026.0 34277.0 26088.0 True False 40529.678300249056 38503.640279646876 31320.29201016947 28337.24989447469 39123.99314779845 28853.85415676496 33105.67326674918 30374.653924622624 30416.36330718826 30597.27603992504 1.3246172060337549 1.2584009187420857 1.0236300763931077 0.9261363612074048 1.2786756931155332 0.9430203564237167 1.0819810633976386 0.9927241197872672 0.9940872928524516 1.0 14.901115600486458 -5.195464463273051 4.090306334560021 1.0332559860553068 1.3072215940740441 0.5585569788562301 0.09351447543579007 0.15967005817997118 5.275062659143035 0.023673220273105814 0.06895972075319033 6.375812498391636e-06 5.195464463273051 0.27396560801873737 S(ph)VPNTPLRPNQQSVVNSSFSELFVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVPNTPLRPNQQSVVNSSFSELFVK 25 1 H0YJ97;Q15643-2;Q15643 H0YJ97 TRIP11 Thyroid receptor-interacting protein 11 1 S(0.556)VPNT(0.397)PLRPNQQS(0.04)VVNS(0.003)S(0.002)FS(0.002)ELFVK 42.347 0.034917000000000004 3172200.0 1693.5 3711.5 3921.6 4110.8 4017.2 3477.2 1777.0 4240.5 1602.4 3378.3 True False 1980.1761018503512 4079.953191551018 4015.1058167508204 3880.4852033934176 3230.0584977114904 3294.849510739241 1608.6696956341082 4129.19136818114 1625.8320685570332 3990.759047391916 0.49619034332440026 1.0223501702558047 1.0061007866097091 0.9723677018108708 0.8093844953687277 0.8256197559440545 0.4030986778531326 1.0346882182425157 0.4073992063288222 1.0 11.96244745962081 -6.85955091741524 3.1379531364889153 0.7057476327660251 0.8874445826563477 0.0697237843876708 0.24042487247827754 0.5826148855141272 11.45915876540811 0.08608285459163574 0.07584346766795523 1.3818123903960962e-07 6.85955091741524 0.1816969498903226 S(ph)VPSETVVEDSR ddPTM_PC-9_AZD4547_30min_R2 2 SVPSETVVEDSR 12 0 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 S(0.991)VPS(0.007)ET(0.002)VVEDSR;S(0.998)VPS(0.002)ETVVEDSR 166.45 6.7939e-05 115879000.0 26414.8 20598.1 25678.3 39688.0 18410.2 28197.2 21822.6 31410.4 20402.4 21661.2 True False 34814.1569380282 27256.033007200516 25337.788964096828 30538.544773487567 15854.261513183861 26434.024626502684 23764.7691240221 26556.644419186327 21480.829211674874 20902.847981156152 1.6655221800116926 1.3039387279557186 1.212169221483061 1.460975308293777 0.7584737509202777 1.2646135421514269 1.1369153689222617 1.2704797185114227 1.0276508364333783 1.0 14.35141190024657 -1.522878750387962 0.6416803648080531 1.1188834622512798 45.48661041026325 0.476747246894476 0.17308275950489999 188.75793261681014 1.2572758223124798 0.07130901350258166 11873.605514554349 0.02999999964717781 1.522878750387962 44.36772694801197 S(ph)VPSETVVEDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SVPSETVVEDSR 12 0 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 S(1)VPSETVVEDSR;S(0.865)VPS(0.038)ET(0.098)VVEDSR;S(0.446)VPS(0.108)ET(0.446)VVEDSR;S(0.839)VPS(0.023)ET(0.137)VVEDSR 206.74 6.7503e-08 139806000.0 16192.6 17172.7 25484.199999999997 16291.0 26186.199999999997 14551.699999999999 21302.6 24445.100000000002 10791.4 14278.099999999999 True False 18933.687361571894 18877.49216557947 26091.839977366708 15378.26808613462 21055.202089209568 13788.583235196205 19284.663510531882 23803.442026724388 10949.203809676957 16866.60650462259 1.1225546381474416 1.1192228952756895 1.5469525520866205 0.9117582770381188 1.2483365923927272 0.8175078508778397 1.1433635749578068 1.411276300315694 0.6491645967240735 1.0 14.04188211776147 -6.935676762599082 0.41901839701110943 0.9721121411518628 1.2325970743269148 0.10349193609263319 0.24136501341778463 3.491915536926662 1.3258093790816876 0.2470759213141486 0.3461176232007856 1.1596401338789457e-07 6.935676762599082 0.26048493317505195 S(ph)VPSETVVEDSR ddPTM_PC-9_Lapatinib_30min_R1 2 SVPSETVVEDSR 12 0 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 S(0.998)VPS(0.002)ET(0.001)VVEDSR;S(0.988)VPS(0.003)ET(0.009)VVEDSR 127.78 0.0002242 71030000.0 13861.0 16866.0 31513.0 17199.0 15179.0 15032.0 14703.0 16396.0 15171.0 15481.0 True False 13663.339598203916 16826.947813243944 28922.12278369777 18463.871834182082 14286.201063062204 14389.116401303472 15464.249397668476 17157.818016540783 13462.282222287618 18156.870222864152 0.7525162338274727 0.9267537635453551 1.592902434654041 1.016908289124154 0.7868206848266293 0.7924888058727152 0.8517023698387745 0.9449766290081587 0.7414428839908298 1.0 14.148227920113708 -6.009446739021285 24.930744978338886 0.8520541057288403 1.11275675180714 0.209579332514364 0.21106188485836144 670.6875469539336 1770009.818067404 0.06318535744372382 0.08812184468658278 9.784829465552864e-07 6.009446739021285 0.2607026460782996 S(ph)VPSIAAATGTHSR ddPTM_PC-9_AZD4547_30min_R2 1 SVPSIAAATGTHSR 14 0 Q8IY63-2;Q8IY63 Q8IY63-2 AMOTL1 Angiomotin-like protein 1 1 S(0.993)VPS(0.007)IAAATGTHSR 138.31 9.6056e-06 0.0 7838.1 7704.7 16465.0 25604.0 21718.0 18173.0 17411.0 22343.0 19257.0 20032.0 True False 10330.452757392026 10195.093601379633 16246.66334196011 19701.393377856675 18702.830579968002 17036.639437158057 18960.54527042373 18890.402741062826 20274.885706055335 19330.68577726626 0.5344069463661292 0.5274046517982054 0.840459750324373 1.0191771572339345 0.9675202833188338 0.881326179187802 0.9808521792187098 0.9772236204511056 1.048844616257717 1.0 14.238605199194383 -5.375889691102367 2.9053020456389222 0.9755555574987039 0.5205003221459873 0.9447290657594966 0.04301925145787911 0.056124419063808634 0.8974882255865795 0.012434731523690044 0.031624878070137925 4.208335046791463e-06 5.375889691102367 -0.45505523535271664 S(ph)VPSIAAATGTHSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVPSIAAATGTHSR 14 0 Q8IY63-2;Q8IY63 Q8IY63-2 AMOTL1 Angiomotin-like protein 1 1 S(0.689)VPS(0.311)IAAATGTHSR;S(0.991)VPS(0.009)IAAATGTHSR 151.3 0.00013723 5961900.0 12312.900000000001 14192.400000000001 27253.0 29946.0 30633.0 24989.0 30496.0 28528.0 28449.0 20794.5 True False 14397.230779139754 15601.327677696003 27902.814877578043 28268.22270624193 24630.683550830447 23678.532849379655 27607.198108079767 27779.17022791452 28865.012804779708 24564.378240828577 0.5861019822276651 0.6351199906116475 1.1359056029841061 1.1507811200878342 1.0026992464190143 0.9639378052737947 1.123871234900369 1.1308721090177085 1.175076060211572 1.0 14.584280102447645 -5.2553693536600425 22.411372132109168 1.0864854109506477 0.610610628328398 0.8814391390532442 0.06965028705060046 36.70898354384393 135529.44094070003 0.01915714450230169 0.04769802961922908 5.5543167934449334e-06 5.2553693536600425 -0.4758747826222497 S(ph)VQEGENPDDGVR ddPTM_PC-9_AZD4547_30min_R2 2 SVQEGENPDDGVR 13 0 H7C5M1;Q5TCT4;A2A2V2;P42696-2;P42696 H7C5M1 RBM34 RNA-binding protein 34 1 S(1)VQEGENPDDGVR;S(1)VQEGENPDDGVR 115.58 0.00028716 63958000.0 32073.0 27585.6 47813.0 61725.0 49196.0 49321.0 44608.0 54931.0 40015.0 49639.0 True False 42271.546840157 36502.10573419057 47178.96837954076 47495.25489174362 42365.98458477324 46236.95007318944 48578.02558285345 46442.67613880509 42130.111207758426 47901.153718935675 0.8824745033948265 0.7620297821712178 0.9849234249422801 0.9915263246147744 0.8844460163393865 0.9652575456634906 1.0141305962668328 0.96955234964301 0.8795218473225226 1.0 15.547772783831203 -5.270647757726362 24.974842806440666 0.9604638298031387 0.8222521408081702 0.5457605283798452 0.050690971658201835 416.4392032010551 1129462.5978892935 0.013091619401101337 0.02786239821852383 5.362314012135774e-06 5.270647757726362 -0.1382116889949685 S(ph)VQEGENPDDGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVQEGENPDDGVR 13 0 H7C5M1;Q5TCT4;A2A2V2;P42696-2;P42696 H7C5M1 RBM34 RNA-binding protein 34 1 S(1)VQEGENPDDGVR;S(1)VQEGENPDDGVR 163.7 8.5881e-05 23665000.0 8136.6 9948.8 9853.8 6975.1 18464.6 19589.6 26147.4 18084.9 20410.3 22147.0 True False 9513.965674824667 10936.451114671367 10088.7519627446 6584.307760579313 14846.594179240159 18562.28689048012 23670.528981217387 17610.19053753545 20708.762025005988 26162.07578444446 0.36365484731458175 0.4180268876513996 0.38562505689029486 0.2516737515336698 0.5674853288234758 0.7095112422813542 0.9047649420575219 0.673119009463545 0.7915565338022252 1.0 14.675189393058046 -6.64716334424741 2.3161574488375667 0.8121076171919447 0.3623406540508144 0.8439273050802457 0.09380541625961068 0.1135857952419337 1.2435538801369823 0.03397080567072466 0.033708782616156924 2.2533915205841012e-07 6.64716334424741 -0.4497669631411303 S(ph)VQEGENPDDGVR ddPTM_PC-9_Lapatinib_30min_R1 2 SVQEGENPDDGVR 13 0 H7C5M1;Q5TCT4;A2A2V2;P42696-2;P42696 H7C5M1 RBM34 RNA-binding protein 34 1 S(1)VQEGENPDDGVR;S(1)VQEGENPDDGVR 170.09 5.8958999999999996e-05 40641000.0 5054.7 4593.1 7401.4 2614.8 6567.4 13919.7 14175.6 12604.0 18723.5 10114.1 True False 4982.619051081545 4582.464959149226 6792.885462230214 2807.101114717094 6181.118444005186 13324.38687940554 14909.543206256507 13189.627853164184 16614.66226280419 11862.308708808878 0.4200378841415148 0.3863046453803985 0.5726444682042257 0.2366403693939071 0.5210721281781451 1.1232540988847248 1.2568837628702725 1.1118938291809626 1.400626359560702 1.0 13.534097202131727 -6.749771661617991 3.86413591757989 1.2010902657343179 0.4106151282641551 0.9051374821249306 0.12217686536107851 0.05783008218570393 1.8895606498368083 0.04069781777747481 0.038325838492220286 1.779214619264224e-07 6.749771661617991 -0.7904751374701628 down S(ph)VQEGENPDDGVRGS(ph)PPEDYR ddPTM_PC-9_Lapatinib_30min_R1 1 SVQEGENPDDGVRGSPPEDYR 21 1 H7C5M1;Q5TCT4;A2A2V2;P42696-2;P42696 H7C5M1 RBM34 RNA-binding protein 34 2 S(1)VQEGENPDDGVRGS(0.909)PPEDY(0.091)R 61.276 0.028324000000000002 3348500.0 7049.1 4363.3 5737.1 3327.0 8150.3 8207.8 6609.2 6761.8 6003.5 4914.9 True False 6948.578541353382 4353.197046930352 5265.417783846433 3571.678678546647 7670.915378106322 7856.771527316306 6951.39203693603 7075.977913164518 5327.322610342345 5764.433916307408 1.20542253450006 0.7551820543237195 0.9134318929306703 0.619606145269959 1.3307317751367633 1.3629736486508655 1.2059106128826897 1.2275234682015856 0.9241709919288885 1.0 12.492963222767207 -6.274095119387605 24.98880210187471 1.1975169625304158 0.8678244061331704 0.3809623861663832 0.1871302047269329 748.5072400346128 1477927.09277876 0.05753989380104487 0.06567604852962848 5.319917294200117e-07 6.274095119387605 -0.3296925563972455 S(ph)VQPTSEER ddPTM_PC-9_AZD4547_30min_R2 2 SVQPTSEER 9 0 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;Q9UHD8-8;Q9UHD8-3;Q9UHD8-9;K7EL40;Q9UHD8-4;K7ER52;K7EK18;K7EQD7;K7ER14;K7EIR4;K7EIE4;K7ELJ9;K7EJZ2;K7ENQ5;K7EN52;K7EKN4 Q9UHD8 SEPT9 Septin-9 1 S(1)VQPTSEER;S(1)VQPTSEER 84.507 0.013153999999999999 19605200.0 22329.2 24419.2 39731.0 67198.0 66895.0 53550.0 35234.0 65430.0 48448.0 46898.0 True False 29429.4211237874 32312.228856517366 39204.14098022576 51706.53929875069 57607.783941751506 50201.510034656545 38369.75774269768 55319.296931823905 51008.86237144773 45256.11529464022 0.6502860648154833 0.713985914304584 0.866272783799205 1.142531544347431 1.272928168197727 1.1092757234645374 0.8478358668854171 1.2223607035572381 1.1271153531264053 1.0 15.465825131063472 -5.52841676737733 2.691219361238319 1.1090059350510486 0.6819909879341784 0.6992845891161144 0.11201694861521214 0.15598266731739305 2.257598423995476 0.03345240428352676 0.07432561891062471 2.9619875765014478e-06 5.52841676737733 -0.42701494711687016 S(ph)VQPTSEER ddPTM_PC-9_Lapatinib_30min_R1 2 SVQPTSEER 9 0 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;Q9UHD8-8;Q9UHD8-3;Q9UHD8-9;K7EL40;Q9UHD8-4;K7ER52;K7EK18;K7EQD7;K7ER14;K7EIR4;K7EIE4;K7ELJ9;K7EJZ2;K7ENQ5;K7EN52;K7EKN4 Q9UHD8 SEPT9 Septin-9 1 S(0.993)VQPT(0.003)S(0.003)EER;S(1)VQPTSEER 99.34299999999999 0.004171500000000001 14974200.0 51955.0 50572.0 53642.0 40191.0 60258.0 61903.0 42944.0 45898.0 67266.0 47486.0 True False 51214.112172619905 50454.9036411344 49231.761824108034 43146.78021324565 56713.74291178618 59255.55299294105 45167.430193394204 48030.58863888682 59689.79473761778 55693.891828882304 0.9195642554478617 0.9059324458085183 0.8839705793118399 0.7747129675515 1.0183117223346025 1.0639506604243394 0.8109943246948819 0.8624031659784032 1.0717475970437254 1.0 15.765231489674921 -6.280132867182634 24.921427289826582 0.9609785234341497 0.8744602530366907 0.2429435303811156 0.08541664289499505 1426.4050028273252 1901623.1555073906 0.028059684009994302 0.03187463404900585 5.246469262660793e-07 6.280132867182634 -0.08651827039745896 S(ph)VRTSCLYNDPEMS(ph)S(ph)MEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVRTSCLYNDPEMSSMEK 18 1 Q5JUB9 Q5JUB9 PRUNE2 3 S(0.323)VRT(0.324)S(0.324)CLY(0.047)NDPEMS(0.986)S(0.996)MEK 43.798 0.046188 0.0 3162.7 4180.1 1119.3 3585.8 4114.3 2430.3 3679.9 3038.5 2288.2 2682.5 True False 3698.0826438276385 4595.07270268151 1145.9883569688889 3384.899251320453 3308.132449749673 2302.850789701363 3331.3132318311514 2958.7425945568666 2321.6605961509003 3168.8160153416825 1.1670234642603217 1.4500913528695478 0.3616455961534646 1.0681905276079813 1.0439648227393121 0.7267227818062686 1.0512801045257112 0.9337060215021148 0.7326586917355515 1.0 11.629728182482681 -5.215176341014346 24.999804001188185 0.8777983285684992 1.3085575988295663 0.40425249750455505 0.21503082325673942 409.61303269843006 221346.96459774752 0.05229553997307828 0.1383603677838752 6.092894510020015e-06 5.215176341014346 0.4307592702610672 S(ph)VS(ph)MLSLNT(ph)PNS(ph)NRK ddPTM_PC-9_Lapatinib_30min_R1 1 SVSMLSLNTPNSNRK 15 1 Q9H8V3-2;Q9H8V3-4;Q9H8V3;Q9H8V3-3;H7C3G1 Q9H8V3-2 ECT2 Protein ECT2 4 S(0.996)VS(0.996)MLS(0.028)LNT(0.98)PNS(1)NRK 58.83 0.032856 0.0 524.13 495.05 0.0 524.66 0.0 607.92 448.44 0.0 825.72 0.0 True False 516.6558100863298 493.9037421407813 0.0 563.2452466144525 0.0 581.9206787307351 471.6580289662281 0.0 732.7187183829242 0.0 0.0 S(ph)VSANPK ddPTM_PC-9_Lapatinib_30min_R1 1 SVSANPK 7 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 S(0.714)VS(0.286)ANPK 88.177 0.017446 20229000.0 50373.0 86685.0 40150.0 93468.0 71505.0 39201.0 149370.0 126930.0 66817.0 72264.0 True False 49654.67178272315 86484.28620841053 36849.021983481936 100341.94852010776 67299.21648423892 37524.46461199427 157103.64772697684 132827.63118074683 59291.36584579741 84754.73611427269 0.5858630922497947 1.020406530341926 0.4347724230277742 1.1839096329061685 0.7940466759698369 0.4427418021973542 1.8536267697790707 1.5672001031500902 0.6995640428383417 1.0 16.371006368183828 -7.2482101874714635 24.998902019107447 1.3273644392805437 0.7644707244752 0.33935940482479776 0.3636196273286483 864.3856727803328 1633412.4025201674 0.1378684123489188 0.10613426840398614 5.646636258529253e-08 7.2482101874714635 -0.5628937148053437 S(ph)VSCDNVSK ddPTM_PC-9_AZD4547_30min_R2 2 SVSCDNVSK 9 0 Q96CB8;A0A087WXN4 Q96CB8 INTS12 Integrator complex subunit 12 1 S(0.932)VS(0.067)CDNVS(0.001)K;S(0.935)VS(0.065)CDNVSK 151.79 0.00013991 141578000.0 101953.0 123237.0 163071.0 217160.0 196135.0 160341.0 143806.0 201406.0 161856.0 148381.0 True False 134371.9332458619 163070.95021911568 160908.5719913013 167097.11708855478 168905.04078653723 150314.85192281727 156604.45541086383 170283.33054945644 170411.37772442683 143186.2263536617 0.9384417528678421 1.1388731610004152 1.1237713018140894 1.166991555988315 1.179617935941349 1.0497856934335867 1.0937117305128208 1.1892437903130881 1.190138060510936 1.0 17.12753319520253 -4.760060878469971 24.974989478576095 1.1312350634436106 0.9384415170102937 0.46642921173981466 0.059860419395184716 30.157466711846002 546177.2314691995 0.014660711744048815 0.08935538541859081 1.737557244625495e-05 4.760060878469971 -0.19279354643331692 S(ph)VSCDNVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVSCDNVSK 9 0 Q96CB8;A0A087WXN4 Q96CB8 INTS12 Integrator complex subunit 12 1 S(0.997)VS(0.002)CDNVS(0.001)K;S(0.868)VS(0.132)CDNVSK 137.01 0.00096947 95861000.0 246497.0 252702.0 218237.0 264720.0 270505.0 264705.0 270086.0 275037.0 220498.0 202929.0 True False 288224.0735623296 277788.58451066364 223440.5977484318 249888.59663381946 217501.48708639052 250823.40381347967 244501.4988266928 267817.5701757899 223722.36610876778 239718.42131491983 1.202344283686432 1.1588120052973767 0.9320960672225364 1.042425505987873 0.907320705239658 1.0463251110934488 1.019952899262128 1.117217311488782 0.9332714811051674 1.0 17.87098125250403 -5.136304932479333 5.396212236663377 1.0049652749016256 1.1913098863733573 0.5918599435824761 0.060255692691517114 0.14536285660371834 5.675858900664125 0.015045986134594118 0.04222779377700018 7.3062590679922e-06 5.136304932479333 0.18634461147173176 S(ph)VSDPVEDK ddPTM_PC-9_AZD4547_30min_R2 1 SVSDPVEDK 9 0 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 S(1)VSDPVEDK 100.88 0.0058732 0.0 16836.0 18296.0 24463.0 27248.0 20019.0 30986.0 27256.0 33449.0 22871.0 24272.0 True False 22189.49778944542 24209.824202219635 24138.604636159747 20966.39457740348 17239.707403093256 29048.440521640852 29681.73119813159 28280.225631553993 24079.914367928097 23422.24466782181 0.9473685423468411 1.033625279966434 1.0305845993198974 0.8951488157839862 0.7360399333022803 1.24020737267545 1.2672453737497351 1.2074088556681428 1.0280788502311997 1.0 14.515591722508798 -6.783799844429188 24.999954539807902 1.168967259941264 0.9382032621378363 0.486527261931609 0.11182956053115034 208.6778943888012 233309.18231307293 0.04123224421619411 0.03639033271476568 1.6451297480810712e-07 6.783799844429188 -0.2307639978034276 S(ph)VSEINSDDELSGK ddPTM_PC-9_AZD4547_30min_R2 2 SVSEINSDDELSGK 14 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 S(0.615)VS(0.385)EINSDDELSGK;S(1)VSEINSDDELSGK 269.87 8.526e-57 66997000.0 81020.0 72653.0 94043.0 100788.0 99495.0 105275.0 96351.0 102574.0 84629.0 83415.0 True False 106782.67467931048 96136.66144314957 92795.92837339545 77552.88375907743 85681.83665871261 98692.13760781444 104926.05234338039 86723.5452160309 89102.31616647216 80494.66623954996 1.3265807496055468 1.1943233748811313 1.1528208353238867 0.9634536967739221 1.064441169353082 1.2260705239041465 1.3035155898544046 1.0773825057916753 1.1069344135337622 1.0 16.29660556967498 -4.849368012856907 2.10689744605714 1.1188554414794278 1.364540874581223 0.32871793674549055 0.09468041057306031 0.790379362160861 4.503860314876506 0.02758603127671767 0.3560506117528588 1.414594571488581e-05 4.849368012856907 0.24568543310179525 S(ph)VSEINSDDELSGK ddPTM_PC-9_Lapatinib_30min_R1 2 SVSEINSDDELSGK 14 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 S(1)VSEINSDDELSGK;S(0.996)VS(0.004)EINSDDELSGK 267.5 6.033499999999997e-166 2538800.0 22957.4 21068.0 21236.4 24359.0 24945.7 20826.0 18479.6 22658.0 23112.5 19139.7 True False 22630.023266128457 21019.218340414074 19490.42516687461 26150.4421192419 23478.44297113319 19935.32052777715 19436.383266622768 23710.77339709568 20509.32686458525 22447.971642952838 1.008109936437521 0.9363526769694893 0.8682488323168076 1.1649356358417973 1.0459048748176698 0.8880677882554038 0.865841403213127 1.0562546039449974 0.9136383095451659 1.0 14.454297471159228 -6.754502190057635 24.998718210655202 0.943343894238798 1.0022329374831678 0.10454594061286993 0.08752665650143968 445.6467207359608 1605922.138897586 0.030949881625389315 0.03030648648665089 1.7599397887651746e-07 6.754502190057635 0.05888904324436972 S(ph)VSGFLHFDTATK ddPTM_PC-9_AZD4547_30min_R2 1 SVSGFLHFDTATK 13 0 Q92621 Q92621 NUP205 Nuclear pore complex protein Nup205 1 S(0.996)VS(0.004)GFLHFDTATK 110.51 0.00066841 2928000.0 8678.2 8761.6 15230.0 10295.0 10417.0 12942.0 13270.0 13594.0 10364.0 11373.0 True False 11437.687082226492 11593.615857573657 15028.040248894773 7921.64680616444 8970.779360508646 12132.734694090113 14451.004292603697 11493.359659043468 10911.819881474648 10974.83473167178 1.0421739699841663 1.0563818172237405 1.369318137021784 0.7218010111171621 0.8173953940846397 1.1055050021916777 1.316740037177981 1.0472467185200793 0.9942582415373162 1.0 13.421911594153565 -7.623620805981993 0.002567364777926907 0.10514183460352727 1.9928124256711695 0.002015767289690773 0.18519002318093192 524960.5884382452 1157.3794292316863 424682.85930756334 426243.4098180864 2.3789164751049554e-08 7.623620805981993 1.8876705910676421 S(ph)VSGFLHFDTATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVSGFLHFDTATK 13 0 Q92621 Q92621 NUP205 Nuclear pore complex protein Nup205 1 S(0.5)VS(0.5)GFLHFDTATK;S(0.5)VS(0.5)GFLHFDTATK 70.45100000000001 0.038114 2354800.0 47609.0 59292.0 54215.0 52354.0 55698.0 48070.0 53761.0 37133.0 46686.0 40697.0 True False 55668.263379387856 65178.11791282312 55507.69121153244 49420.775113958094 44784.37673143849 45549.124577601324 48668.368884066 36158.298095665676 47368.69442876536 48075.04394272524 1.1579451377248637 1.355757843726026 1.1546051060850233 1.0279923024685345 0.9315514466256728 0.9474588235814573 1.0123416411651671 0.7521219978237208 0.9853073558330722 1.0 15.553000555802564 -5.779690412695768 2.0193894424401337 0.93010395444817 1.2595579712761447 0.707411484689578 0.08290056015878962 0.16078131314980085 1.3386956194020947 0.02468815777272405 0.04768600628246717 1.6607703675748211e-06 5.779690412695768 0.3294540168279747 S(ph)VSGS(ph)PEPAAK ddPTM_PC-9_Lapatinib_30min_R1 1 SVSGSPEPAAK 11 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 2 S(1)VS(0.034)GS(0.966)PEPAAK 120.84 0.010018 3953400.0 40754.0 35660.0 39610.0 31281.0 45615.0 43903.0 37399.0 36352.0 39533.0 36847.0 True False 40172.84048663174 35577.43146094388 36353.41869902166 33581.50909035698 42932.01538254049 42025.37103289161 39335.33722528761 38041.046629500495 35080.37723905458 43215.95485445871 0.9295835443628293 0.8232476079901602 0.8412036439192776 0.7770627584986077 0.9934297535973818 0.9724503640940781 0.9102040521321322 0.8802546827349736 0.811745971070109 1.0 15.399276417398578 -6.258952069050531 24.999963826504793 0.9233581774723549 0.841267425295049 0.3022798146497574 0.06318937004795899 313.88491442668135 3154859.850754483 0.0198518276628539 0.02440703261578818 5.508684897009134e-07 6.258952069050531 -0.08209075217730588 S(ph)VSGSPEPAAK ddPTM_PC-9_AZD4547_30min_R2 1 SVSGSPEPAAK 11 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 S(0.963)VS(0.035)GS(0.001)PEPAAK 116.24 0.0020513000000000003 0.0 16500.0 17236.0 25400.0 28292.0 28269.0 23828.0 20654.0 27975.0 24101.0 26530.0 True False 21746.6567786796 22807.199931649437 25063.179403934828 21769.7165070427 24344.337308459137 22338.031393198813 22492.16598790028 23652.1065515478 25374.929656833334 25601.192775103522 0.8494392026854173 0.8908647394674841 0.9789848318437765 0.8503399313571502 0.9509063707427474 0.8725386972954617 0.8785592993844143 0.9238673666232006 0.9911620087291314 1.0 14.643923407377823 -8.19893521203284 3.0517768726737566 0.9998545320107529 0.8984687505089208 0.5041991798899681 0.03891606388142207 0.21463251917634243 3.6738933038668105 0.03281373482228465 0.009997740138152158 6.32506201491789e-09 8.19893521203284 -0.10138578150183208 S(ph)VSGSPEPAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVSGSPEPAAK 11 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 S(0.771)VS(0.021)GS(0.207)PEPAAK 160.72 0.001234 31419000.0 124700.0 112060.0 140600.0 140150.0 144450.0 129700.0 131190.0 131770.0 114910.0 108360.0 True False 145809.24706273354 123184.57622125995 143952.4372284693 132297.84987243084 116146.05944300145 122898.30367619908 118762.73346665113 128311.17712185554 116590.34136163822 128004.81022271203 1.1390919357565084 0.9623433369959654 1.1245861540516362 1.0335381119057125 0.907356991045275 0.9601069167820468 0.9277989886475293 1.0023934014558553 0.9108278131016007 1.0 16.965838499928175 -6.087430314122797 5.45914075973079 0.9513545511831085 1.0664066029864818 0.5260181179878713 0.053617804900686114 0.17542219291676572 8.403016739194003 0.014849178108148247 0.019504073241438692 8.176542263037903e-07 6.087430314122797 0.1150520518033733 S(ph)VSGSPEPAAK ddPTM_PC-9_Lapatinib_30min_R1 3 SVSGSPEPAAK 11 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 S(0.985)VS(0.004)GS(0.011)PEPAAK;S(0.992)VS(0.007)GSPEPAAK;S(0.836)VS(0.131)GS(0.034)PEPAAK 182.41 0.00012305 33372200.0 245113.0 200641.0 223956.0 221529.0 223391.0 206085.0 185233.0 181078.0 233880.0 172489.0 True False 241617.64367178062 200176.42809184667 205543.20217515965 237820.98165907993 210251.58058360426 197271.22495759875 194823.45838797005 189491.54493773874 207537.97153441608 202303.4938228545 1.1943325303286716 0.9894857686794555 1.016014099860984 1.17556537044944 1.039287936211865 0.9751251509790423 0.963025673489187 0.9366696608001518 1.0258743811718105 1.0 17.62616171018758 -6.615418908357587 4.184474266223513 0.9754898158033689 1.0835960219208345 0.4172126454541707 0.06258919013844375 0.23058487116902684 7.479291362521391 0.02129338875809537 0.02132952008734531 2.4242705830866776e-07 6.615418908357587 0.10810620611746558 S(ph)VSGTDVQEECR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSGTDVQEECR 12 0 P49321;P49321-3;P49321-4;E9PPR5 P49321 NASP Nuclear autoantigenic sperm protein 1 S(0.487)VS(0.487)GT(0.027)DVQEECR 86.738 0.032001 0.0 5971.0 7715.3 7437.9 5268.4 5788.3 6673.1 6832.2 8104.4 7378.7 5923.1 True False 5885.8524450527075 7697.435696876614 6826.38457312429 5655.855710867195 5447.843574235649 6387.707068755869 7185.937885788651 8480.960010566787 6547.633104844356 6946.899942965353 0.8472631667903759 1.108038946878928 0.9826519208811837 0.814155343721985 0.7842121837025023 0.91950468859484 1.0344092969217666 1.2208265672740646 0.9425258976811223 1.0 12.76215360283271 -7.3120629302192075 4.449133642769941 1.071468436341777 0.9112565798874067 0.281057149716226 0.10862968016172918 0.28578617171129816 12.340540240726547 0.04936787341380652 0.033212808750330405 4.874578512780768e-08 7.3120629302192075 -0.1602118564543703 S(ph)VSLTGAPESVQK ddPTM_PC-9_Lapatinib_30min_R1 1 SVSLTGAPESVQK 13 0 A0A087WTP3;Q92945;M0R0I5;M0QXW7;M0QYH3 A0A087WTP3 KHSRP Far upstream element-binding protein 2 1 S(0.948)VS(0.052)LTGAPESVQK 96.37100000000001 0.011875 0.0 13211.0 11794.0 11410.0 9868.6 11505.0 10627.0 10311.0 11405.0 18050.0 12306.0 True False 13022.608717399313 11766.691717621197 10471.913843873697 10594.369764684545 10828.298519700278 10172.50798274694 10844.85312788953 11934.917935999487 16017.018925073602 14433.075703285716 0.9022753697907018 0.8152587819478068 0.7255497067398979 0.7340341021195307 0.7502419264131758 0.7048052814155994 0.7513889174308619 0.8269143861888344 1.1097439834966913 1.0 13.817091151939001 -8.145908183659243 4.280597556074614 1.052642036904087 0.7660555117313942 0.7839094416419788 0.058965307719335336 0.10207142258556913 2.9920794859248288 0.04637057861791893 0.01605617342711324 7.146473972404371e-09 8.145908183659243 -0.2865865251726928 S(ph)VSPCSNVESR ddPTM_PC-9_AZD4547_30min_R2 1 SVSPCSNVESR 11 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.859)VS(0.141)PCSNVESR 169.09 0.0022739 17266000.0 39759.0 30763.0 32661.0 57843.0 45274.0 40850.0 37985.0 51511.0 39667.0 46253.0 True False 52401.53496142554 40706.53814674701 32227.893799681715 44508.19001544146 38988.486586125386 38295.643042310374 41365.59141330454 43551.158555023394 41763.716638214486 44633.696548317486 1.1740352920287278 0.91201359723098 0.7220529844485081 0.9971880766644511 0.8735213437658929 0.8579984631309675 0.9267794203091578 0.9757461721297896 0.9356992556734316 1.0 15.44584567462413 -10.459561020985486 5.725559388181043 1.0000000626621954 0.9232471727595661 0.031503866475063314 0.10891325030497727 8.673968652873456e-08 1.6132881747652575e-08 0.10506483975634602 0.025481946075278088 3.4708750458052296e-11 10.459561020985486 -0.0767528899026293 S(ph)VSPCSNVESR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSPCSNVESR 11 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.957)VS(0.043)PCSNVESR 153.49 0.00042626 14244000.0 68412.0 92471.0 65639.0 87968.0 84703.0 67422.0 74325.0 81017.0 76411.0 64659.0 True False 67436.4323347757 92256.88908090135 60242.41479386721 94437.46017264533 79720.93607250531 64538.51822835833 78173.18482498196 84781.3455870994 67804.78853649856 75835.22199729805 0.8892494880173016 1.2165440629182622 0.7943856852692223 1.24529813041241 1.051238909478576 0.8510361877843224 1.0308295112232573 1.1179679224796109 0.8941068114617556 1.0 16.21058044956157 S(ph)VSPLLSTHVLGK ddPTM_PC-9_AZD4547_30min_R2 1 SVSPLLSTHVLGK 13 0 Q96H12;X6RL08;X6R907;Q96H12-2 Q96H12 MSANTD3 Myb/SANT-like DNA-binding domain-containing protein 3 1 S(0.499)VS(0.499)PLLST(0.001)HVLGK 59.88399999999999 0.033794 23872000.0 72484.0 75456.0 276660.0 484280.0 341280.0 312160.0 183770.0 379530.0 233090.0 312360.0 True False 95532.40423914028 99845.67637749702 272991.3076335675 372636.7280514153 293899.1629216072 292640.58585281734 200125.1739903374 320882.3592317754 245410.66153733348 301424.371474984 0.3169365627990329 0.3312461958165963 0.9056709857192943 1.2362528160147177 0.9750345052838525 0.9708590729436235 0.6639316290552383 1.0645534654732 0.8141699370108856 1.0 18.201436544274394 -5.273662956295323 5.182755831367365 0.9597530211594735 0.3162576181938146 0.7620428388101839 0.14098698154529488 0.07643760439779412 6.762246451075337 0.03801750607810478 0.09021671759521374 5.325213737692458e-06 5.273662956295323 -0.6434954029656589 down S(ph)VSPLVWCR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSPLVWCR 9 0 Q9P270 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 S(0.926)VS(0.074)PLVWCR 84.81700000000001 0.012915000000000001 3530900.0 25864.0 19427.0 30705.0 22423.0 18563.0 16930.0 19659.0 18840.0 18645.0 11277.0 True False 25495.174617123295 19382.017975091316 28180.553424727575 24072.062220935237 17471.16083626219 16205.943365757574 20676.846827774247 19715.375178801434 16545.00375944584 13226.214424342024 1.9276244735758263 1.4654244482396956 2.130659047297995 1.8200266114416008 1.3209494626147602 1.2252896290514952 1.5633231221262978 1.4906287276362702 1.2509251119500824 1.0 13.691112575502165 -6.474442349133138 0.18620293785165837 0.8772844269886058 2.2837104949206544 0.5582360762072052 0.2208479952678057 6.480761899426828 0.4816540616928334 0.8899256170686725 2.5177196304180054 3.353958239585816e-07 6.474442349133138 1.4064260679320486 S(ph)VSPSPSVLSEGR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSPSPSVLSEGR 13 0 C9IYE1;A0A087X1P3;Q86UW7-3;Q86UW7-2;Q86UW7 C9IYE1 CADPS2 Calcium-dependent secretion activator 2 1 S(0.539)VS(0.354)PS(0.107)PSVLSEGR 110.15 0.0015517999999999999 0.0 15797.0 19194.0 20717.0 22370.0 22360.0 23252.0 24856.0 23702.0 17393.0 17619.0 True False 15571.731883184986 19149.557472275847 19013.728229932625 24015.164424132417 21044.828761451397 22257.566163059375 26142.92205865794 24803.28144840507 15434.017183590318 20664.42067415822 0.7535527914730332 0.9266922007749882 0.9201191037361207 1.1621503841220409 1.0184088435524783 1.077096063520109 1.2651175888686215 1.2002892236617444 0.746888452715795 1.0 14.334861297956577 -5.023283731303227 1.1599549929675308 1.0817768281123077 0.6946409608643254 0.31796772326036105 0.13795464249463993 1.2597644882834396 1.9045964590967883 0.04402613918314627 0.5356662870852219 9.477990492059595e-06 5.023283731303227 -0.3871358672479823 S(ph)VSPSPVPLLFQPDQNAPPIR ddPTM_PC-9_AZD4547_30min_R2 1 SVSPSPVPLLFQPDQNAPPIR 21 0 Q02241-2;Q02241-3 Q02241-2 KIF23 Kinesin-like protein KIF23 1 S(0.333)VS(0.333)PS(0.333)PVPLLFQPDQNAPPIR 47.105 0.035827 4899500.0 7339.3 8246.2 10616.0 12159.0 11663.0 9368.7 9893.5 12092.0 9776.7 9760.5 True False 9673.04473307655 10911.622886769992 10475.22490362882 9355.930404677369 10043.793768034204 8782.873707968014 10774.002333750908 10223.459246517108 10293.476402471371 9418.787865864988 1.0269946484444166 1.1584954499628608 1.1121627382216037 0.9933263746797586 1.0663573605298327 0.9324845015140838 1.1438841692992585 1.0854325834822507 1.0928663591390966 1.0 13.201325691376352 -8.383021868392612 0.005845186515073642 1.0772649130243682e-07 2.1067663847536866 0.04412801131834798 0.06674589188970333 15765.338090685913 69.99354311411344 12685.627448985744 12535.444771025881 4.1397882887332315e-09 8.383021868392612 2.1067662770271953 S(ph)VSPSPVPLSSNYIAQISNGQQLMSQPQLHR ddPTM_PC-9_AZD4547_30min_R2 1 SVSPSPVPLSSNYIAQISNGQQLMSQPQLHR 31 0 Q02241;H7BYN4 Q02241 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 S(0.302)VS(0.286)PS(0.302)PVPLS(0.05)S(0.05)NY(0.009)IAQIS(0.001)NGQQLMS(0.001)QPQLHR 41.434 0.037686000000000004 8858000.0 7225.2 7426.5 16021.0 25498.0 14553.0 15434.0 11800.0 16606.0 12538.0 18046.0 True False 9522.663306503988 9826.970891877143 15808.551072064569 19619.830040172987 12532.567153065398 14468.909540147331 12850.177140371028 14039.92426791789 13200.733083165685 17414.21503277491 0.5468327621188548 0.5643074277756429 0.9077957888030923 1.126656010807661 0.7196745376968258 0.8308677429855847 0.7379130851540533 0.8062335420513447 0.7580435327300643 1.0 14.08797782268102 -5.253611548395186 24.091583034476663 0.8529606314341855 0.5555700078881975 0.5107979498776056 0.11931940854703522 304.0890170953176 935879.4113188311 0.03190794944425073 0.08099842492577448 5.576843427034694e-06 5.253611548395186 -0.297390623545988 S(ph)VSPTFLNPSDENLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVSPTFLNPSDENLK 15 0 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 S(0.928)VS(0.071)PTFLNPSDENLK;S(0.939)VS(0.059)PT(0.003)FLNPSDENLK 257.16 4.8338e-50 150996000.0 73590.0 78174.0 88809.0 88998.0 101446.0 81151.0 91066.0 80606.0 79651.0 58296.0 True False 86047.33353124712 85934.59808603246 90926.54337000802 84011.73059540911 81568.3845362044 76895.2987018291 82439.56921925463 78490.17790911673 80815.74519011255 68864.60332911788 1.2495146907331987 1.2478776313476116 1.320366908024601 1.2199551951806076 1.1844747605148116 1.1166157210596408 1.1971254495616455 1.1397753579439975 1.173545497733832 1.0 16.071475002195818 -14.522878731445363 0.04379389180344191 0.03192804798251296 1.7290241096056038 0.7746088834827277 0.039403684589642815 338.588703425456 1.099561223567982 40.54346845009367 10.851243801585095 3.000000095568618e-15 14.522878731445363 1.6970960616230908 S(ph)VSPTVNPMS(ph)TAMQNERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVSPTVNPMSTAMQNERR 18 1 Q13873-2 Q13873-2 2 S(0.997)VS(0.003)PT(0.138)VNPMS(0.645)T(0.217)AMQNERR 60.093 0.03578 0.0 700.97 0.0 801.09 0.0 0.0 712.12 728.76 1402.1 0.0 0.0 True False 819.6303762114209 0.0 820.1910237507432 0.0 0.0 674.7751735843871 659.7265770345035 1365.2963606477485 0.0 0.0 0.0 S(ph)VSQDLIK ddPTM_PC-9_AZD4547_30min_R2 3 SVSQDLIK 8 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 S(0.994)VS(0.006)QDLIK;S(0.996)VS(0.004)QDLIK;S(0.996)VS(0.004)QDLIK 119.03 0.0034773000000000004 128493700.0 354655.0 345225.0 313699.0 327964.0 318824.0 284479.0 297110.0 424558.0 355703.0 317595.0 True False 467427.91271773446 456812.2300071753 309539.1462927143 252356.96679328973 274560.79090283223 266690.4831587124 323552.2144216637 358952.3164722807 374504.73439793265 306476.09571839374 1.525169235865076 1.4905313542851912 1.0099944191965138 0.8234148448078916 0.8958636407164134 0.8701836354759672 1.0557176202053957 1.1712245146913671 1.221970455868921 1.0 18.225415026547246 -5.257601223670372 5.882172908991431 0.9976427973560409 1.5134235143404322 0.7407506417890533 0.11874270379083719 0.08063473523772238 12.225230607904177 0.03551768976454717 0.0864674122545737 5.5258459866266945e-06 5.257601223670372 0.5157807169843913 S(ph)VSQDLIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SVSQDLIK 8 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 S(1)VSQDLIK;S(1)VSQDLIK;S(0.999)VS(0.001)QDLIK;S(0.993)VS(0.007)QDLIK 98.75399999999999 0.0054093000000000006 118961000.0 348900.0 521758.0 339158.0 317882.0 389401.0 259575.0 230601.0 257358.0 192933.0 203303.0 True False 407961.87891088624 573554.6860615046 347244.8129838769 300072.1021273486 313100.6693884673 245962.43004432824 208756.80387333815 250602.62519334076 195754.2801316242 240160.22455433744 1.6987071013442645 2.3882168128625105 1.4458881091914995 1.249466278956846 1.3037157588001285 1.024159727118668 0.8692397097009954 1.0434809746633988 0.815098672125591 1.0 17.873637705455742 -5.701215736744988 1.1027826229890494 0.9678320414267021 2.0970142491916097 0.7706044252760429 0.21510156118543008 0.2588329451527649 0.5923733771151554 0.07658258492801048 0.23663495357944025 1.989684713172004e-06 5.701215736744988 1.1291822077649076 S(ph)VSQDLIK ddPTM_PC-9_Lapatinib_30min_R1 3 SVSQDLIK 8 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 S(0.999)VS(0.001)QDLIK;S(0.982)VS(0.018)QDLIK;S(0.995)VS(0.005)QDLIK 117.25 0.0035548000000000003 103299000.0 195030.0 320119.0 324463.0 327218.0 339053.0 289095.0 306383.0 297178.0 303272.0 410503.0 True False 192248.83643587798 319377.7841235528 297786.904603399 351282.70328724926 319110.569143845 276731.0807633599 322246.0125964677 310985.9747816264 269114.3137642617 481457.89658913505 0.39930560449388297 0.6633555839174496 0.6185107913133334 0.7296228928342321 0.6628005717728762 0.5747773226357854 0.6693129656391635 0.6459255876470017 0.5589571085463317 1.0 18.877050114586673 -11.59310954938951 2.5227857586766036 1.5691934763999238 0.6215297348908562 0.6454102307191218 0.08573739659922308 6621485.302080157 2289950.5433148965 21691987.751087204 0.02149185476985222 2.5520574731540537e-12 11.59310954938951 -0.9476637415090676 S(ph)VSQDLIKK ddPTM_PC-9_AZD4547_30min_R2 1 SVSQDLIKK 9 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 S(0.923)VS(0.077)QDLIKK 66.56 0.022057 27429000.0 107990.0 108560.0 103650.0 134040.0 136400.0 112170.0 106610.0 145470.0 127890.0 133570.0 True False 142328.57366846138 143649.89699349392 102275.53327629314 103139.14889735612 117463.21443538253 105155.99216783243 116098.08346906422 122990.95406804836 134650.00430739022 128893.75495554386 1.1042317272667808 1.114482986728407 0.793487111238 0.8001873243038762 0.911318119918969 0.8158346554811852 0.900726986416891 0.954204135882833 1.044658869266643 1.0 16.97582283966525 -10.890920971323528 14.737796698945708 0.9999994311887416 0.9296363845290349 0.022266447017581292 0.11309349049133971 8.140200513980646e-11 6.015435460646561e-11 0.11898976132328012 0.02885925613546582 1.285520565162736e-11 10.890920971323528 -0.07036304665970672 S(ph)VSQDLIKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVSQDLIKK 9 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 S(0.986)VS(0.014)QDLIKK 88.441 0.0083795 0.0 26464.0 28748.0 22424.0 19757.0 29452.0 24942.0 21480.0 26798.0 17210.0 18714.0 True False 30943.83251217462 31601.91145108681 22958.67320349358 18650.07934305823 23681.092022951027 23633.99761211842 19445.258898267097 26094.580894828014 17461.66369187877 22106.700060057505 1.399749054725906 1.4295173574180482 1.0385391370544457 0.8436392266774944 1.0712178642048047 1.0690875412391578 0.8796092969751232 1.1803924070049618 0.7898810606938387 1.0 14.432196064934105 -5.29528888549589 4.878140556853518 0.9852150613728713 1.418512043862899 0.7069711297151577 0.11120432659975095 0.08978541827693322 5.559959408476918 0.027538748987783686 0.06335229454834125 5.066535785921129e-06 5.29528888549589 0.4332969824900278 S(ph)VSSENPTYPSAPLKPVTVPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVSSENPTYPSAPLKPVTVPPR 22 1 A0A0U1RQE4;A0A494C1M0;Q5HYK7-2;Q5HYK7;A0A0U1RQN2;Q5HYK7-3 A0A0U1RQE4 SH3D19 SH3 domain-containing protein 19 1 S(0.437)VS(0.437)S(0.126)ENPTYPSAPLKPVTVPPR 77.907 0.00032604 5280900.0 10758.0 9814.4 7029.4 12874.0 9800.6 9686.7 9618.2 10240.0 5787.4 5958.5 True False 12579.116919814634 10788.708770890027 7197.007555147956 12152.711518071139 7880.242784195768 9178.712399539236 8707.094466262226 9971.210850176834 5872.0297763148865 7038.728882539952 1.7871290583471675 1.5327637917198595 1.0224868261371205 1.7265491711460532 1.1195548110601687 1.3040298259402574 1.237026544360981 1.4166209576435178 0.8342457671414022 1.0 12.78109920209976 -1.5228787452803376 0.1952938485078647 1.0034424826335158 4.071403643251404 0.42962246706624474 0.22750745952694124 56.77616340316603 0.67563263425319 0.43072903184238226 52.91771108207911 0.029999999999999995 1.5228787452803376 3.0679611606178883 S(ph)VSSFPVPQDNVDTHPGSGK ddPTM_PC-9_AZD4547_30min_R2 2 SVSSFPVPQDNVDTHPGSGK 20 0 C9JAY7;E7EVC7;Q676U5-4;Q676U5-5;Q676U5-3;Q676U5-2;Q676U5 C9JAY7 ATG16L1 Autophagy-related protein 16-1 1 S(0.941)VS(0.029)S(0.029)FPVPQDNVDTHPGSGK;S(0.952)VS(0.039)S(0.008)FPVPQDNVDTHPGSGK 145.2 7.0875e-05 94740000.0 196688.0 201071.0 358374.0 512068.0 511301.0 382743.0 285319.0 533869.0 356788.0 423825.0 True False 259230.69263545098 266063.2685922886 353621.7266025878 394018.6339717353 440315.6818476931 358810.01970484626 310711.8382638575 451371.81313916965 375647.0852828617 408987.0157522908 0.6338359963790586 0.650542091422858 0.8646282473103356 0.9634013276606773 1.0766006374011077 0.8773139632436767 0.7597107641481824 1.1036336014455526 0.9184816896739286 1.0 18.641695516608415 -5.353694410036729 2.677064689974353 0.9540522874057668 0.6298380464757154 0.6451333190875461 0.09213820560517677 0.17883989843526063 2.4498982965140637 0.026295451758555004 0.0718919143425546 4.428999078888072e-06 5.353694410036729 -0.32421424093005136 S(ph)VSSFPVPQDNVDTHPGSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SVSSFPVPQDNVDTHPGSGK 20 0 C9JAY7;E7EVC7;Q676U5-4;Q676U5-5;Q676U5-3;Q676U5-2;Q676U5 C9JAY7 ATG16L1 Autophagy-related protein 16-1 1 S(0.682)VS(0.159)S(0.159)FPVPQDNVDTHPGSGK;S(0.634)VS(0.183)S(0.183)FPVPQDNVDTHPGSGK;S(0.912)VS(0.044)S(0.044)FPVPQDNVDTHPGSGK;S(0.831)VS(0.157)S(0.012)FPVPQDNVDTHPGSGK;S(0.867)VS(0.066)S(0.066)FPVPQDNVDTHPGSGK;S(0.915)VS(0.042)S(0.042)FPVPQDNVDTHPGSGK 234.62 3.6077e-44 94161300.0 501800.0 476291.0 637184.0 653579.0 978496.0 760820.0 630658.0 826157.0 649679.0 542642.0 True False 586744.828998233 523574.02278244094 652376.8830937756 616961.0875617061 786766.7329923103 720921.2598529359 570917.5086714762 804471.2541356987 659179.3263030859 641018.6990482928 0.9153318458094294 0.8167843208938841 1.017718958998148 0.9624697196473292 1.227369395246046 1.1246493447434105 0.8906409587101056 1.2549887473330816 1.0283308853263653 1.0 19.290006916508233 -5.619421299463301 1.7767302978090005 1.0884797992440942 0.8680397754290028 0.3487120061108786 0.10881272604127096 0.38154116584013315 2.396301698408479 0.03246271385651027 0.08023358715534967 2.402031511826252e-06 5.619421299463301 -0.22044002381509142 S(ph)VSSFPVPQDNVDTHPGSGK ddPTM_PC-9_Lapatinib_30min_R1 3 SVSSFPVPQDNVDTHPGSGK 20 0 C9JAY7;E7EVC7;Q676U5-4;Q676U5-5;Q676U5-3;Q676U5-2;Q676U5 C9JAY7 ATG16L1 Autophagy-related protein 16-1 1 S(0.96)VS(0.04)SFPVPQDNVDTHPGSGK;S(0.822)VS(0.177)S(0.001)FPVPQDNVDTHPGSGK;S(0.609)VS(0.196)S(0.196)FPVPQDNVDTHPGSGK 188.54 9.3027e-12 29745500.0 175668.0 144832.0 201387.0 187950.0 159094.0 203116.0 154972.0 170166.0 246168.0 188230.0 True False 173162.9421064341 144496.65040245175 184829.73823630085 201772.4699828199 149736.4037108385 194429.20216652175 162995.69187618027 178072.53358152433 218441.96757603955 220765.30469929043 0.7843757076878696 0.654526084156539 0.8372227623722929 0.9139682082637889 0.6782605804603126 0.8807054280171348 0.7383211419846996 0.8066146708337213 0.9894759861545475 1.0 17.75215393155583 -8.249626757535426 4.350088200311607 1.0010490071530485 0.7849024699622672 0.5407864058804954 0.07691542078938736 0.14942012105585567 7.039432493922127 0.06370084934009773 0.019578467208411044 5.628248217317323e-09 8.249626757535426 -0.21614653719078125 S(ph)VSSPTSSNTPTPTK ddPTM_PC-9_AZD4547_30min_R2 3 SVSSPTSSNTPTPTK 15 0 Q5M775;Q5M775-4;Q5M775-2;Q5M775-5;Q5M775-3 Q5M775 SPECC1 Cytospin-B 1 S(0.995)VS(0.005)SPTSSNTPTPTK;S(0.99)VS(0.01)SPTSSNTPTPTK;S(0.992)VS(0.008)SPTSSNTPTPTK 210.9 8.286399999999999e-39 45955000.0 32651.7 27104.9 37697.100000000006 36806.0 60629.0 35808.0 31726.3 67573.0 46266.0 42865.3 True False 43034.26140244924 35866.02885979141 37197.21182315242 28320.945347031422 52211.70988271847 33568.920099364725 34549.879238012974 57131.14552306486 48711.52630608896 41364.598894181894 1.0403645279515135 0.8670706308924494 0.8992523272934327 0.6846662630400819 1.2622317459498504 0.811537425643606 0.8352523694572211 1.38116038956927 1.1776138922729997 1.0 15.336108972189464 -7.750008432578475 24.999906415258753 1.2095403806830194 0.9125339899015708 0.3515647269329575 0.168329734546842 208.29324632408236 455547.46479118784 0.077760385869247 0.04438873713663612 1.7782448820038703e-08 7.750008432578475 -0.29700639078144864 S(ph)VSSPTSSNTPTPTK ddPTM_PC-9_Lapatinib_30min_R1 1 SVSSPTSSNTPTPTK 15 0 Q5M775;Q5M775-4;Q5M775-2;Q5M775-5;Q5M775-3 Q5M775 SPECC1 Cytospin-B 1 S(0.995)VS(0.004)S(0.001)PTSSNTPTPTK 149.31 0.00013299 26661000.0 61851.0 35772.0 46703.0 59066.0 30397.0 23266.0 21910.0 20945.0 45678.0 49005.0 True False 60968.99339791576 35689.17213182513 42863.259618793425 63409.91067839984 28609.108222801337 22270.967415694973 23044.39259354666 21918.18116348174 40533.26262933587 57475.448954942054 1.060783247569105 0.6209463828599877 0.7457664167598956 1.1032521160140936 0.49776224010410913 0.3874866194286594 0.4009432377224637 0.3813485855615416 0.705227420861244 1.0 15.810658209784576 -6.291360720505048 24.28068982020049 0.5144040651255185 0.8542112477274373 0.3191505692987593 0.22136965430317807 530.6748981525277 430632.5395576219 0.0666615536117288 0.07559917680897263 5.112570143501618e-07 6.291360720505048 0.3398071826019188 S(ph)VSSSPWLPQDGFDPSDYAEPMDAVVKPR ddPTM_PC-9_AZD4547_30min_R2 1 SVSSSPWLPQDGFDPSDYAEPMDAVVKPR 29 1 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 S(0.471)VS(0.15)S(0.173)S(0.2)PWLPQDGFDPS(0.005)DYAEPMDAVVKPR 86.079 2.3891e-08 9441800.0 13531.0 11230.0 13197.0 19320.0 17623.0 18273.0 18114.0 11072.0 10325.0 19043.0 True False 17833.57653771598 14859.877885380773 13021.999157233384 14866.072491024483 15176.350645122757 17130.386421349758 19726.11090853227 9361.076809248882 10870.758421094728 18376.310366238085 0.9704655712868648 0.8086431709752854 0.708629692125688 0.8089802683316236 0.8258649501809426 0.9321994502673723 1.0734532947796807 0.5094100296895039 0.5915637146109075 1.0 14.1655595079458 -7.771328098138021 24.99999868803538 0.6628652279099876 0.8641933478156739 0.20235817843416914 0.15290657043221295 292.27788105637467 738905.0164380849 0.08206275884882745 0.040168332308641475 1.693058255884511e-08 7.771328098138021 0.20132811990568633 S(ph)VSSSPWLPQDGFDPSDYAEPMDAVVKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVSSSPWLPQDGFDPSDYAEPMDAVVKPR 29 1 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 S(0.919)VS(0.027)S(0.027)S(0.027)PWLPQDGFDPSDYAEPMDAVVKPR 80.583 3.3027999999999995e-06 4682200.0 9168.2 9381.7 12617.0 12052.0 18681.0 23205.0 23364.0 22779.0 25323.0 21086.0 True False 10720.195179795923 10313.053174504705 12917.837130238959 11376.765513111182 15020.592152680567 21988.08894993218 21150.792779288302 22181.075386345532 25693.300968590698 24908.724883315852 0.43037912338003426 0.41403376619300597 0.5186069215004849 0.45673817372849423 0.6030253344177217 0.8827464694774501 0.8491318956858905 0.8904942139853441 1.031498042912681 1.0 14.604363549197164 -6.697850772250801 1.2042856131415993 0.9595462640550758 0.43477962971746237 0.947615846555077 0.053538554955764955 0.09629184211222304 0.2952148329432735 0.02657299097239265 0.025451796043569196 2.0051609015232935e-07 6.697850772250801 -0.5247666343376134 down S(ph)VSSSPWLPQDGFDPSDYAEPMDAVVKPR ddPTM_PC-9_Lapatinib_30min_R1 2 SVSSSPWLPQDGFDPSDYAEPMDAVVKPR 29 1 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 S(0.553)VS(0.05)S(0.199)S(0.199)PWLPQDGFDPSDYAEPMDAVVKPR;S(0.519)VS(0.16)S(0.16)S(0.16)PWLPQDGFDPSDYAEPMDAVVKPR 106.76 1.1412e-11 12581200.0 17476.6 15843.1 12833.2 15438.9 20337.8 28629.0 26708.0 26808.0 32424.0 25198.0 True False 17227.38047918407 15806.416275347165 11778.103833584564 16574.328208660605 19141.570589653227 27404.60440745858 28090.809556752356 28053.59754741553 28772.067680143307 29553.440725775523 0.5829230051091454 0.5348418284697841 0.3985357895506257 0.560825670433867 0.6476934705257039 0.9272898090528322 0.9505089379407688 0.9492497948960684 0.9735606742753737 1.0 14.85103848386234 -6.650698232389766 2.1097799374383066 0.967397993127192 0.5100250110525287 0.9513237564226809 0.047715597733869006 0.06530932163685069 0.5948755954010236 0.019071761825711003 0.018894764679540887 2.2351247499846634e-07 6.650698232389766 -0.45737298207466326 S(ph)VSTPSEAGSQDSGDGAVGSR ddPTM_PC-9_AZD4547_30min_R2 1 SVSTPSEAGSQDSGDGAVGSR 21 0 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E9PGG1;E7ETL8;E7ESD3;E7EMU4;Q13409;Q13409-7;Q13409-5;E7ET01;E7ERR6;E7EUM4;E7ERH4 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 1 S(0.759)VS(0.078)T(0.163)PS(0.001)EAGSQDSGDGAVGSR 173.03 6.478799999999999e-10 7907200.0 8052.7 8840.6 11206.0 11000.0 8831.9 9073.8 8747.7 9710.3 10891.0 10575.0 True False 10613.291093434738 11698.15106264446 11057.401118129668 8464.11994830586 7605.743134691013 8506.413851586683 9526.228353459632 8209.796255495785 11466.676025582829 10204.772468779493 1.040032114964353 1.1463411946159323 1.0835519510071105 0.8294276010759682 0.7453123681062016 0.8335721230053122 0.9335071783916985 0.8045055664506834 1.1236581766682214 1.0 13.31695639515644 -5.75013958212613 23.13430296350295 0.8802852720190818 1.0956119816326073 0.41125588443916516 0.10532400213895404 78.26426530268404 160227.7315440715 0.028505378297718393 0.048701076975657655 1.7777079633656604e-06 5.75013958212613 0.2153267096135255 S(ph)VSTPSEAGSQDSGDGAVGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVSTPSEAGSQDSGDGAVGSR 21 0 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E9PGG1;E7ETL8;E7ESD3;E7EMU4;Q13409;Q13409-7;Q13409-5;E7ET01;E7ERR6;E7EUM4;E7ERH4 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 1 S(0.932)VS(0.053)T(0.016)PSEAGSQDSGDGAVGSR;S(0.705)VS(0.017)T(0.074)PS(0.198)EAGS(0.001)QDS(0.001)GDGAVGS(0.003)R 234.62 5.079699999999999e-51 14777000.0 19566.6 12553.7 22970.0 21352.1 22030.9 21788.9 19699.7 18088.8 15694.4 19709.9 True False 22878.838922034298 13799.948371487006 23517.691914210107 20155.81106144219 17714.10329513893 20646.25172683374 17833.60180252292 17613.988166667845 15923.900909112266 23283.148846517444 0.982635083976469 0.5927011188416261 1.010073511501334 0.8656823522586798 0.7608121827468582 0.8867465420134478 0.7659445859356074 0.7565122863225796 0.6839238547192499 1.0 14.506998563141535 -7.280710621047274 23.72565442770516 0.7813045354778186 0.842055529482111 0.019699829315197426 0.13322445784087136 1597.2853277882405 1966474.2459465556 0.0529188081580855 0.0357581287844565 5.239494381124611e-08 7.280710621047274 0.0607509940042924 S(ph)VSTPSEAGSQDSGDGAVGSR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSTPSEAGSQDSGDGAVGSR 21 0 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E9PGG1;E7ETL8;E7ESD3;E7EMU4;Q13409;Q13409-7;Q13409-5;E7ET01;E7ERR6;E7EUM4;E7ERH4 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 1 S(0.975)VS(0.007)T(0.007)PS(0.011)EAGSQDSGDGAVGSR 239.56 1.9649999999999997e-51 7403500.0 11411.0 15291.0 14580.0 9800.0 13288.0 13133.0 14459.0 12202.0 14292.0 10697.0 True False 11248.277047478881 15255.59462897623 13381.288680427566 10520.724691841644 12506.425965213162 12571.332204518269 15207.616271569648 12768.949465591031 12682.284458567967 12545.962197143448 0.8965655141253309 1.2159764543567435 1.066581300832734 0.8385745570185981 0.9968486887407259 1.002022165137768 1.2121522472809796 1.0177736282752672 1.010865827529399 1.0 13.614935500261808 S(ph)VSVATGLNMMK ddPTM_PC-9_Lapatinib_30min_R1 1 SVSVATGLNMMK 12 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 S(0.59)VS(0.284)VAT(0.125)GLNMMK 167.98 0.00094395 17599000.0 66048.0 77642.0 69839.0 67308.0 67241.0 70479.0 76891.0 65155.0 67882.0 45486.0 True False 65106.14340828021 77462.2247193104 64097.10700633613 72258.05485290589 63286.0165808924 67464.77746457339 80872.03974944747 68182.33916002166 60236.41433085028 53348.1944937148 1.220400128367056 1.4520121150198735 1.2014859662005564 1.3544611122953552 1.1862822571876996 1.2646121973728977 1.5159283367870189 1.2780627312149155 1.1291181435942883 1.0 15.703151825125081 -8.418755401915801 2.7132065190728922 1.0056513735112653 1.3140204415729673 0.5035758047066905 0.10132012139284245 0.20411299311053088 3.001210179484766 0.09562549606698349 0.025988346144844417 3.812805031258486e-09 8.418755401915801 0.30836906806170195 S(ph)VSVVTGSEQK ddPTM_PC-9_AZD4547_30min_R2 1 SVSVVTGSEQK 11 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 S(0.966)VS(0.034)VVTGSEQK 127.56 0.00035422 55098000.0 74983.0 75320.0 109000.0 142840.0 103480.0 77207.0 163320.0 166990.0 134830.0 116400.0 True False 98826.03425671106 99665.717037122 107554.58878066523 109910.4448560009 89113.5881948195 72379.23408488766 177855.1636072368 141185.5325484525 141956.8385390995 112324.87142940242 0.8798232572990253 0.8872987413100503 0.9575313767286582 0.9785049691784511 0.79335579966213 0.6443740657239827 1.583399663350792 1.2569391867694177 1.2638059294670203 1.0 16.77731788494477 -7.25618017384242 24.99972803235063 1.2974477949845022 0.8654252531160729 0.6275030619240551 0.15780698919758535 279.79885640608865 1330032.378797042 0.06118440963351927 0.045947501184426545 5.5439566554935276e-08 7.25618017384242 -0.43202254186842937 S(ph)VSVVTGSEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVSVVTGSEQK 11 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 S(0.996)VS(0.004)VVTGSEQK 165.58 0.0018184999999999998 14889000.0 88214.0 84214.0 63295.0 92038.0 91489.0 86564.0 100610.0 132590.0 99032.0 82844.0 True False 103146.88789408148 92574.20936906304 64804.19284762426 86881.40925122188 73562.38720928169 82024.43145278729 91079.49244667862 129109.65299071738 100480.15564986272 97862.96140725682 1.0539931186512494 0.9459575720768899 0.6621932538699861 0.8877864311674035 0.7516877289575545 0.8381560324078333 0.9306840007390662 1.319290272173835 1.0267434604979349 1.0 16.578475320024467 -7.567914706661396 8.79582874714875 1.1298752163990304 0.8514109780584763 0.453308297193618 0.12673766803447192 0.25158088102531795 45.13193023499544 0.05960499022470863 0.03438533579939259 2.7044894606221266e-08 7.567914706661396 -0.2784642383405541 S(ph)VTPASTLTK ddPTM_PC-9_AZD4547_30min_R2 1 SVTPASTLTK 10 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 S(0.988)VT(0.012)PASTLTK 121.29 0.00063498 13514000.0 49109.0 38961.0 54740.0 87940.0 90868.0 88153.0 59857.0 79136.0 59350.0 75681.0 True False 64724.64046934397 51554.38132611934 54014.111833519375 67666.79165945612 78252.54669585297 82640.77897451122 65184.15704162618 66907.34956437127 62487.119834573576 73031.43122550352 0.8862573193929313 0.7059204572745096 0.7396008941237475 0.9265434145815563 1.071491348077623 1.131578247718251 0.8925493578285925 0.9161445755838666 0.8556195433392009 1.0 16.156229883457726 -5.8687418509213805 4.731836101882777 0.9786676085858133 0.7708947577786563 0.5069226664442238 0.08827330567652368 0.17919962571990417 6.6676600065873926 0.027354971177942618 0.04179350384831351 1.352876487851137e-06 5.8687418509213805 -0.2077728508071569 S(ph)VTPASTLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVTPASTLTK 10 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 S(0.49)VT(0.444)PAS(0.027)T(0.038)LT(0.001)K 96.756 0.0054084 14126000.0 60444.0 78907.0 109390.0 101230.0 131880.0 94299.0 73277.0 72496.0 86361.0 80504.0 True False 70675.97537658256 86740.36548180437 111998.27246388524 95558.41129208832 106039.06070850143 89353.79443609805 66335.6720804618 70593.05681586126 87623.86624603951 95098.73793068643 0.7431852084945163 0.9121084818709778 1.1777051399516594 1.0048336431313833 1.1150417241687156 0.939589697827792 0.6975452411241372 0.7423132877674322 0.9213988340192796 1.0 16.537138574544628 -7.012640426840572 23.578949347993845 0.818801413784216 1.0003950706316103 0.2084964746068776 0.13508016243581827 391.3956850607003 730093.8147183431 0.051532903118314724 0.042038456147827134 9.713138315675111e-08 7.012640426840572 0.18159365684739426 S(ph)VTPDSLGHTPPAR ddPTM_PC-9_Lapatinib_30min_R1 2 SVTPDSLGHTPPAR 14 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 S(0.496)VT(0.496)PDS(0.008)LGHTPPAR;S(0.548)VT(0.45)PDS(0.001)LGHTPPAR 91.932 0.0073452 0.0 53805.0 63248.0 75504.0 47848.0 64565.0 73226.0 50692.0 59216.0 68745.0 45771.0 True False 53037.73083337142 63101.55314194557 69296.35257386834 51366.90153624888 60767.413639673934 70094.29467814321 53316.58372213905 61967.39153863616 61002.21418305728 53682.45636397612 0.9879900143496908 1.1754594967507892 1.290856590168441 0.9568657065163452 1.1319790068409055 1.3057207032944256 0.9931845025988305 1.1543322667369538 1.1363528853719354 1.0 15.712163066420048 -10.96106909321803 2.663134222546366 0.9958837870786609 1.1296065253058138 0.09921709173740645 0.11326446147195282 13900858.29774751 14580691.32177314 430353.4428289757 0.027677218295178833 1.093782339300352e-11 10.96106909321803 0.13372273822715297 S(ph)VTPPEEQQEAEEPK ddPTM_PC-9_AZD4547_30min_R2 3 SVTPPEEQQEAEEPK 15 0 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4;P30305-3 G8JLH2 CDC25B M-phase inducer phosphatase 2 1 S(0.981)VT(0.019)PPEEQQEAEEPK;S(0.899)VT(0.101)PPEEQQEAEEPK;S(0.951)VT(0.049)PPEEQQEAEEPK 139.0 2.3208000000000002e-05 33257000.0 150217.0 125694.0 133196.0 132256.0 140282.0 138034.0 146113.0 146152.0 143950.0 159155.0 True False 197982.88129229788 166322.1274198621 131429.7340112795 101766.42253483097 120806.26574358008 129402.71215917438 159116.77394161292 123567.56663884969 151558.90312025064 153583.0318930118 1.2890934555206313 1.0829459828330812 0.8557568657899357 0.6626150120914592 0.786586019657012 0.8425586509408033 1.036030946780996 0.8045652251801402 0.9868206223837853 1.0 17.22865930796958 -2.7891633656663313 8.974529040652524 0.9197770564208064 1.0168308152984753 0.0 0.1716599635782892 0.0 0.0 0.04197159309119743 0.0 0.0016249373988804136 2.7891633656663313 0.09705375887766887 S(ph)VTPPEEQQEAEEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SVTPPEEQQEAEEPK 15 0 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4;P30305-3 G8JLH2 CDC25B M-phase inducer phosphatase 2 1 S(0.995)VT(0.005)PPEEQQEAEEPK;S(0.73)VT(0.27)PPEEQQEAEEPK;S(0.982)VT(0.018)PPEEQQEAEEPK;S(0.739)VT(0.261)PPEEQQEAEEPK 219.03 5.4973e-18 40605200.0 125998.0 132836.0 98707.1 123228.0 129105.0 100108.0 117240.0 116530.0 107544.0 86265.0 True False 147326.97282606494 146023.08019745967 101060.65161276153 116323.93467056626 103807.80203799703 94858.16024993786 106134.17845590498 113471.21097374067 109116.62754674091 101904.16162663585 1.445740492580201 1.4329452091708486 0.9917225165252345 1.141503279294546 1.018680693516089 0.9308565885413624 1.0415097554579507 1.1135090968069101 1.0707769516472805 1.0 16.636853444836625 -5.256440265020311 24.87525380963899 1.0418477128229955 1.4393429118003416 0.8858486134409623 0.05753692265581456 118.04271861074866 587367.3110586095 0.015596800565302032 0.038646760437394144 5.540637473259634e-06 5.256440265020311 0.3974951989773461 S(ph)VTPPEEQQEAEEPK ddPTM_PC-9_Lapatinib_30min_R1 4 SVTPPEEQQEAEEPK 15 0 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4;P30305-3 G8JLH2 CDC25B M-phase inducer phosphatase 2 1 S(0.85)VT(0.15)PPEEQQEAEEPK;S(0.872)VT(0.128)PPEEQQEAEEPK;S(0.946)VT(0.054)PPEEQQEAEEPK;S(0.989)VT(0.011)PPEEQQEAEEPK 220.34 3.6147000000000005e-18 41195100.0 144444.0 166373.0 153100.0 188761.0 170068.0 149292.0 139862.0 148803.0 164933.0 144081.0 True False 142384.20207221463 165987.77354042698 140512.70898309076 202643.1136282368 160064.93460655265 142907.12917664959 147103.37000997807 155716.93061205887 146356.5087185132 168985.20887413513 0.8425838155945727 0.9822621438072682 0.8315089226995513 1.1991766319570076 0.9472126920041473 0.8456783296524536 0.8705103304014302 0.921482605782623 0.8660906460015894 1.0 17.36653744864958 -6.538314704260087 23.220864848569644 0.8942315876831738 0.9704221587442694 0.07800488237319425 0.10185770856057595 241.13173844473903 362737.7688097125 0.033406509353458375 0.03342285149414688 2.8952448364504944e-07 6.538314704260087 0.07619057106109561 S(ph)VVADTDQK ddPTM_PC-9_AZD4547_30min_R2 2 SVVADTDQK 9 0 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 S(1)VVADTDQK;S(1)VVADTDQK 101.95 0.0033326000000000002 9635200.0 74469.0 71774.0 108688.0 95823.0 108552.0 98915.0 106126.0 114750.0 86183.0 86341.0 True False 98148.59294857537 94973.5418829313 107246.72610452236 73732.487800592 93481.42854391244 92729.8294132221 115571.00840669643 97018.02419267582 90738.45743391833 83318.22787015518 1.177996645602354 1.1398891252336762 1.287194037199853 0.8849502646107429 1.1219805189519367 1.1129596942188227 1.3871035349768197 1.164427360887592 1.0890588980760247 1.0 16.346344533976882 S(ph)VVADTDQK ddPTM_PC-9_Lapatinib_30min_R1 1 SVVADTDQK 9 0 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 S(0.999)VVADT(0.001)DQK 77.64 0.022764 5357500.0 64506.0 66966.0 49141.0 32021.0 38037.0 37884.0 31234.0 34130.0 51438.0 19183.0 True False 63586.13261104836 66810.94434137887 45100.81666974562 34375.931158924635 35799.73844361927 36263.78963191732 32851.143690864264 35715.80439769071 45644.51077384686 22498.755990259222 2.826206597314883 2.969539487885663 2.004591573386186 1.5279036393748884 1.5911874620587323 1.6118130996939404 1.4601315603888092 1.5874568537546596 2.028757091885815 1.0 14.457557613156194 -5.409618956027863 2.860351206010378 1.571905217062265 2.917517429299391 0.8304496349344413 0.24122300817653827 0.09650083959625702 1.4998415474566742 0.0633703129648286 0.15645087733668925 3.893866376125543e-06 5.409618956027863 1.345612212237126 S(ph)VVEAQVT(ph)GVLDDCLCDIDSIDNFNT(ph)Y(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 SVVEAQVTGVLDDCLCDIDSIDNFNTYK 28 0 Q86YB8-2;Q86YB8 Q86YB8-2 ERO1LB ERO1-like protein beta 4 S(1)VVEAQVT(1)GVLDDCLCDIDS(0.218)IDNFNT(0.894)Y(0.888)K 40.937 0.021374 16534000.0 19051.0 19442.0 14739.0 14504.0 21568.0 20167.0 17048.0 17375.0 20187.0 23134.0 True False 25108.82171458332 25726.2462909682 14543.551229708488 11160.32688456621 18573.655490779536 18905.954301940583 18565.238973647905 14690.092987779906 21254.043607422707 22324.085701441592 1.1247413242532884 1.152398652962836 0.6514735440551247 0.4999231338663748 0.8320007250993545 0.8468859399119633 0.8316237100115166 0.6580378334074969 0.9520678200070793 1.0 14.446313469520488 -5.251496807662113 24.634257579524025 0.7673039093118807 1.1385700642921526 0.4984309016371181 0.14148212035384078 440.64322749626115 1091754.6970430457 0.036560792623466655 0.09421126548456119 5.604065366899388e-06 5.251496807662113 0.3712661549802718 S(ph)VVGTPAYLAPEVLLNQGYNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVVGTPAYLAPEVLLNQGYNR 21 0 Q9BZL6-2;Q9BZL6;Q9BZL6-3 Q9BZL6-2 PRKD2 Serine/threonine-protein kinase D2 1 S(0.959)VVGT(0.04)PAY(0.001)LAPEVLLNQGYNR 95.554 0.00034495 18445000.0 9585.5 8296.4 9781.0 6952.4 7360.2 3164.6 2337.6 2466.7 1963.4 1923.6 True False 11208.135827745227 9120.011763002525 10014.216134649061 6562.879567984917 5918.021645637785 2998.6428050400923 2116.1656052415824 2401.9517386846883 1992.1110106121307 2272.333452790778 4.932434460259297 4.0135006382103535 4.407018750857207 2.8881674738030556 2.6043808131986683 1.3196315009829624 0.9312742382252933 1.0570419300630014 0.8766807565876871 1.0 11.14995884282714 -6.240222411113167 0.9065537289127792 0.8647761925570759 4.706768390190289 0.9637519498247246 0.2870593889215299 0.09573779790842828 0.1674763176481453 0.13338940554578865 0.22192105070259713 5.75145318187542e-07 6.240222411113167 3.841992197633213 up S(ph)VVGTPAYLAPEVLLNQGYNR ddPTM_PC-9_Lapatinib_30min_R1 1 SVVGTPAYLAPEVLLNQGYNR 21 0 Q9BZL6-2;Q9BZL6;Q9BZL6-3 Q9BZL6-2 PRKD2 Serine/threonine-protein kinase D2 1 S(0.999)VVGT(0.001)PAYLAPEVLLNQGYNR 246.42 2.7761999999999995e-61 42816000.0 28414.0 49571.0 37325.0 42104.0 39258.0 21531.0 39059.0 46296.0 37971.0 39536.0 True False 28008.811149510555 49456.221395133136 34256.28257866659 45200.468614826605 36948.921624197625 20610.169321212437 41081.28390284521 48447.081171857266 33694.30612764375 46369.744921591424 0.6040320298693005 1.0665622913984272 0.7387636623102413 0.9747836372888831 0.796832539982183 0.44447450284798956 0.885950180927484 1.0447993892090306 0.7266441983801913 1.0 15.500896170066778 -10.66889607566265 4.565779225038983 1.0000211614605028 0.8176674559274901 0.08567956547469413 0.18513340879143544 4.31166465728602e-05 8.06452985786386e-06 0.17829938580329463 0.043238500971533735 2.143403444691455e-11 10.66889607566265 -0.18235370553301267 S(ph)VVGTPAYLAPEVLR ddPTM_PC-9_AZD4547_30min_R2 3 SVVGTPAYLAPEVLR 15 0 Q15139;F8WBA3;H0Y5M6;O94806 Q15139;O94806 PRKD1;PRKD3 Serine/threonine-protein kinase D1;Serine/threonine-protein kinase;Serine/threonine-protein kinase D3 1 S(0.999)VVGT(0.001)PAYLAPEVLR;S(0.999)VVGT(0.001)PAYLAPEVLR;S(1)VVGTPAYLAPEVLR 180.27 6.1004999999999994e-06 27497300.0 22145.9 20826.4 24844.199999999997 35754.5 31915.9 26694.3 22595.0 24273.9 21463.9 26070.5 True False 29187.83553666425 27558.1265175507 24514.74967508809 27511.852426518366 27484.92819353537 25025.101201085577 24605.91122768503 20522.926513730705 22598.437934579684 25157.779730242608 1.160191235062649 1.0954117101368286 0.9744401110889161 1.093572355013741 1.0925021400237183 0.9947261431422132 0.9780637040122356 0.815768590622476 0.8982683757030318 1.0 14.618716984059564 -7.199813197852178 1.8505251842960388 0.8965351985025527 1.0777324919962379 0.5886049284969812 0.06299789599985345 0.2416294918284847 1.620482867223029 0.03222876482901253 0.021184764089374718 6.312287951755492e-08 7.199813197852178 0.18119729349368519 S(ph)VVGTPAYLAPEVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SVVGTPAYLAPEVLR 15 0 Q15139;F8WBA3;H0Y5M6;O94806 Q15139;O94806 PRKD1;PRKD3 Serine/threonine-protein kinase D1;Serine/threonine-protein kinase;Serine/threonine-protein kinase D3 1 S(0.997)VVGT(0.003)PAYLAPEVLR;S(1)VVGTPAYLAPEVLR;S(0.999)VVGT(0.001)PAYLAPEVLR;S(1)VVGTPAYLAPEVLR 212.35 5.885800000000001e-14 21148400.0 37838.4 31909.4 31754.1 29434.4 32656.9 14409.3 25211.3 24630.8 16379.900000000001 15194.2 True False 44243.69377753432 35077.15435012206 32511.23817209486 27785.285995612347 26258.01487451816 13653.650941877078 22823.103149994473 23984.267598489805 16619.425049773672 17948.78818277898 2.4649961505470364 1.954290952287071 1.8113333246245489 1.5480313051034291 1.4629408184621342 0.7607004329672304 1.2715679140886051 1.3362611087862515 0.9259357724060298 1.0 14.131598822945309 -4.906642020157454 0.528164354313929 1.0459166814553977 3.238764431466473 0.8568158898152318 0.18621533528886916 1.4102093225040402 0.3311255656101042 0.11721518057830055 1.8853182232662655 1.2398181215597889e-05 4.906642020157454 2.192847750011075 up S(ph)VVGTPAYLAPEVLR ddPTM_PC-9_Lapatinib_30min_R1 3 SVVGTPAYLAPEVLR 15 0 Q15139;F8WBA3;H0Y5M6;O94806 Q15139;O94806 PRKD1;PRKD3 Serine/threonine-protein kinase D1;Serine/threonine-protein kinase;Serine/threonine-protein kinase D3 1 S(0.999)VVGT(0.001)PAYLAPEVLR;S(1)VVGTPAYLAPEVLR;S(1)VVGTPAYLAPEVLR 225.31 2.7268e-24 21275200.0 25886.0 26039.6 28677.9 21465.4 23948.7 20067.3 22106.7 23779.1 18767.8 20873.3 True False 25516.860893088982 25979.30690606824 26320.113761895307 23044.037122475278 22540.08455095578 19209.068358161087 23251.276757086172 24883.96379587247 16653.9727303045 24481.222093076045 1.04230339466206 1.0611932201463052 1.075114373858785 0.9412943943265298 0.9207091241303157 0.7846449938295332 0.9497596430719962 1.0164510456735054 0.6802753827806127 1.0 14.57938795815243 -5.9142553867151175 2.8576754371520185 0.8913572911354076 1.06085726411568 0.38579256576511733 0.09417645839990932 0.2719314618871776 4.488537821659274 0.02745216374537325 0.04348443461445353 1.2182729832496274e-06 5.9142553867151175 0.1694999729802723 S(ph)VVSDLEADDVK ddPTM_PC-9_AZD4547_30min_R2 2 SVVSDLEADDVK 12 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 S(1)VVSDLEADDVK;S(1)VVSDLEADDVK 171.73 7.1992e-05 7290500.0 16417.699999999997 19493.2 21966.9 20062.7 19684.3 21637.0 31802.0 40575.0 32038.0 24348.0 True False 21638.18709062594 25793.995689697655 21675.604553082507 15437.554480625098 16951.47472075071 20284.034969558605 34632.316391362656 34305.06607074358 33731.46327312668 23495.583930954424 0.9209469811098653 1.0978231384032626 0.9225395128199315 0.6570406816017363 0.7214749278232608 0.8633126560789689 1.4739925806115448 1.4600644177031126 1.4356512003384145 1.0 14.52010200273958 -7.254832776300479 24.38174598692395 1.3807657585535253 0.8612859669726372 0.654134010219985 0.16955918050356045 223.29019575087742 824057.141923113 0.06867633188049625 0.051893393232023306 5.561183476392601e-08 7.254832776300479 -0.5194797915808882 S(ph)VVSDLEADDVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVVSDLEADDVK 12 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 S(1)VVSDLEADDVK 151.74 0.00019146 2976700.0 10962.0 16386.0 10394.0 13824.0 14716.0 7788.6 15607.0 14967.0 9117.0 9264.2 True False 12817.65009063097 18012.693788698634 10641.832379464513 13049.486098012698 11832.505439689914 7380.152104953317 14128.591975104973 14574.132108847334 9250.318877330552 10943.726124633147 1.1712327176919954 1.6459379176306326 0.9724139893734087 1.1924170935381608 1.0812135926040967 0.6743728800322762 1.2910220718428833 1.3317339946988014 0.8452622783120534 1.0 13.417816410757826 -5.2772941235207576 24.949498380744167 1.0620023975302852 1.40858534502008 0.3072454135153878 0.2154896959452578 849.1994726240371 1336325.203955283 0.05609817220589955 0.11737103505244237 5.280874863305356e-06 5.2772941235207576 0.3465829474897948 S(ph)VVSDLEADDVK ddPTM_PC-9_Lapatinib_30min_R1 3 SVVSDLEADDVK 12 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 S(0.997)VVS(0.003)DLEADDVK;S(1)VVSDLEADDVK;S(0.579)VVS(0.421)DLEADDVK 180.28 0.00073697 12513500.0 30388.3 57138.1 47809.9 47707.4 57844.0 58567.0 67517.0 57644.0 53792.0 53285.0 True False 29954.957269468283 57005.80024000436 43879.154573551 51215.96134322102 54441.72964567953 56062.22593634518 71012.69989678188 60322.350679768 47733.37850512794 62495.241252200496 0.47931581140049684 0.9121622558421143 0.7021199325637613 0.8195177795464174 0.8711340024431476 0.8970639173966097 1.1362897154074347 0.9652311035385277 0.7637922111941158 1.0 15.931458718392479 -4.04828623955193 0.4740828524308807 0.9609539634034806 6.495858378979212e-12 0.5012406576240693 0.12061527196207902 8.425823061713917 0.8647689893998387 0.07779629795854019 5.236009014483465 8.947748331886751e-05 4.04828623955193 -0.9609539633969848 S(ph)VVSFDK ddPTM_PC-9_AZD4547_30min_R2 3 SVVSFDK 7 0 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 1 S(0.999)VVS(0.001)FDK;S(0.993)VVS(0.007)FDK;S(0.517)VVS(0.483)FDK 112.41 0.009174 59137000.0 231565.0 288009.0 350309.0 308151.0 293560.0 355344.0 341691.0 300069.0 291967.0 273481.0 True False 305197.8531487842 381102.276927038 345663.6737721658 237111.54783549078 252804.26121444936 333124.2835061625 372100.837056823 253700.23094964784 307399.7795575558 263906.5134311376 1.156461995502892 1.4440806025292772 1.3097959170392415 0.8984679641010885 0.9579311170749668 1.262281400997275 1.4099721610467832 0.961326144062174 1.1648055804343271 1.0 18.009667432447863 -5.576578354244416 24.660584884468236 1.1063121654956651 1.319438365028957 0.2589481678023373 0.1611190956524027 111.78848558667266 51336.1298960208 0.04603246631309052 0.07973058386947977 2.6510727504319275e-06 5.576578354244416 0.21312619953329182 S(ph)VVSFDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVVSFDK 7 0 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 1 S(0.967)VVS(0.033)FDK;S(0.999)VVS(0.001)FDK 129.42 0.0044245 34265100.0 201477.0 354694.0 267704.0 255177.0 269517.0 169320.0 274378.0 187380.0 182141.0 166094.0 True False 235583.076747861 389905.67622901744 274087.07863307424 240880.2599849956 216707.0785939725 160440.56112917533 248386.9295153041 182461.47354552115 184804.4675480821 196205.52740061958 1.2006954129627494 1.9872308461162456 1.396938619743537 1.2276935475582067 1.1044901816221115 0.8177168260993074 1.2659527629317937 0.9299507305569668 0.9418922595933885 1.0 17.582006159424836 -5.853853867041041 1.9410858025336082 1.009971129058077 1.6049027659003274 0.5513950926745355 0.2114658230292526 0.22720694196144312 1.7467467309364355 0.06326206526885376 0.11549264314691293 1.4000583399558575e-06 5.853853867041041 0.5949316368422504 S(ph)VVSFDK ddPTM_PC-9_Lapatinib_30min_R1 5 SVVSFDK 7 0 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 1 S(0.993)VVS(0.007)FDK;S(0.951)VVS(0.049)FDK;S(0.998)VVS(0.002)FDK;S(0.679)VVS(0.321)FDK;S(0.558)VVS(0.442)FDK 112.41 0.009174 122531900.0 291353.0 393686.0 345204.0 329549.0 323131.0 358818.0 401654.0 384816.0 305101.0 256010.0 True False 287198.2527924032 392774.44425499585 316822.65964597533 353785.1328032366 304125.0698799887 343472.1905856111 422449.6788118842 402695.95619987615 270737.31252403784 300260.98738811724 0.9564953985219894 1.3081101466814793 1.055157589408878 1.1782587404401428 1.012869079414825 1.1439121464742241 1.4069416159809862 1.3411531071778948 0.9016732905566679 1.0 18.195857513574452 -7.010511635648084 24.835971044001738 1.2029507712724583 1.1115490228521483 0.004630763454634423 0.1651408791196907 1494.0961197754045 3530120.4415029567 0.05941636777420122 0.04923232075518666 9.760866306987202e-08 7.010511635648084 -0.09140174842031001 S(ph)VVSFDKVK ddPTM_PC-9_Lapatinib_30min_R1 1 SVVSFDKVK 9 1 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 1 S(0.709)VVS(0.291)FDKVK 117.25 0.0090226 33647000.0 76223.0 131030.0 105900.0 91022.0 104320.0 111330.0 113570.0 130380.0 83662.0 80841.0 True False 75136.04604241367 130726.60808545894 97193.31078582176 97716.06152049096 98184.10270101124 106568.67542290555 119450.09889772204 136437.9307755907 74239.10456008361 94814.25913613856 0.7924551299243922 1.3787652751444888 1.0250917074220582 1.0306051263891212 1.0355415271455544 1.1239730858402794 1.2598326452797595 1.439002234671127 0.7829951447860577 1.0 16.532816422196554 -6.981032891075027 9.195379764587075 1.1619966332754235 1.0689489641187546 0.00810930790215525 0.20811892379866256 0.9050841510642277 394.9792488125027 0.07153153591306104 0.06238000731045718 1.044641100854383e-07 6.981032891075027 -0.09304766915666884 S(ph)WASPVYTEADGTFSR ddPTM_PC-9_AZD4547_30min_R2 4 SWASPVYTEADGTFSR 16 0 E9PMS6;E9PJ10;E9PK58;E9PLU6;Q8WWI1-3;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.982)WAS(0.018)PVYTEADGTFSR;S(0.995)WAS(0.005)PVYTEADGTFSR;S(0.984)WAS(0.016)PVYTEADGTFSR;S(0.999)WAS(0.001)PVYTEADGTFSR 205.28 6.3012e-17 58586500.0 62059.4 56659.6 86599.1 118150.0 108198.2 93244.3 70331.9 100814.2 85367.9 80709.6 True False 81792.99828429017 74973.70766113266 85450.73935115334 90912.34289930342 93176.74756687974 87413.71918066342 76591.30284905613 85235.68186984984 89880.27291197806 77883.98147009019 1.0501902540216328 0.9626332173314077 1.0971542252750524 1.16727908850187 1.1963531628472595 1.1223581220514893 0.9834025097762819 1.094392970942079 1.154027711673867 1.0 16.249039016821996 -5.348997971277753 6.810752221331383 1.1079484602826337 1.0069270586375572 0.24205285380759045 0.0670130603976273 0.3189432392237059 20.884002173575006 0.0184776472200036 0.038915843541159074 4.477153955869139e-06 5.348997971277753 -0.10102140164507656 S(ph)WASPVYTEADGTFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SWASPVYTEADGTFSR 16 0 E9PMS6;E9PJ10;E9PK58;E9PLU6;Q8WWI1-3;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.5)WAS(0.5)PVYTEADGTFSR;S(1)WASPVYTEADGTFSR 147.1 3.0026e-05 23218900.0 33180.5 37341.3 44201.3 52045.2 57856.0 55397.6 44633.3 37392.3 40407.4 40288.4 True False 38797.30330525278 41048.29748394562 45255.22662636373 49129.27617681501 46519.532122771096 52492.4523340988 40405.310706891316 36410.791745416725 40998.281781709615 47592.367997201065 0.8152001032504723 0.8624974804018933 0.9508925176621852 1.0322931647297804 0.9774578168816256 1.10295945638145 0.8489871886447755 0.7650552657425675 0.8614465618546391 1.0 15.53844261830562 -10.499805913884256 6.405065381746379 1.0000000231366217 0.9173679869733061 0.06418815509398246 0.09840631340906034 3.623918617766805e-08 5.804822241738344e-09 0.10617551798758908 0.025751338136042985 3.1636911972435454e-11 10.499805913884256 -0.0826320361633156 S(ph)WASPVYTEADGTFSR ddPTM_PC-9_Lapatinib_30min_R1 4 SWASPVYTEADGTFSR 16 0 E9PMS6;E9PJ10;E9PK58;E9PLU6;Q8WWI1-3;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.999)WAS(0.001)PVYTEADGTFSR;S(0.975)WAS(0.025)PVYTEADGTFSR;S(1)WASPVYTEADGTFSR;S(0.986)WAS(0.014)PVYTEADGTFSR 221.78 7.7173e-23 49831000.0 49091.6 44678.8 58613.0 39783.5 50831.4 47477.7 39783.7 43718.4 50167.2 38440.4 True False 48391.544781703116 44575.348983657284 53794.06539272293 42709.31130386553 47841.5969903775 45447.18944692433 41843.50532286086 45749.71646586586 44516.84165196413 45084.771921386666 1.0733456712630685 0.9887007759822396 1.1931759461159628 0.94731124243762 1.0611475882321828 1.0080385795489795 0.9281072863321227 1.0147487614141344 0.9874030577239512 1.0 15.460352602756387 -5.808094090164032 24.999970280364945 0.99384634312002 1.075438947742373 0.34883310825211233 0.057553736913116986 142.77998655008943 76508.04434158995 0.015775307302509957 0.02339862957917078 1.5556285672171722e-06 5.808094090164032 0.08159260462235296 S(ph)WDQQIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SWDQQIK 7 0 E7EUV9;F8W8D3;Q14493;H0YAE8;Q14493-2 E7EUV9 SLBP Histone RNA hairpin-binding protein 1 S(1)WDQQIK 83.883 0.020366 4848300.0 24911.0 22815.0 22449.0 25741.0 29111.0 27645.0 30702.0 29558.0 21286.0 25028.0 True False 29127.94028532276 25079.922420917825 22984.269298306604 24298.81522344798 23406.908525062034 26195.247533758877 27793.68429676892 28782.133819289757 21597.267480844348 29565.378278460994 0.9852043836876284 0.8482868774653589 0.7774048781595037 0.8218672189677404 0.7916999506857135 0.8860109039376869 0.9400753825976652 0.973508052161746 0.7304918366824488 1.0 14.851621115538135 -6.986546998326339 21.853297244180638 0.9094157363630783 0.8399329130212949 0.11736766180268365 0.08544193444033096 111.46450519172733 181060.6295802052 0.02997049376944112 0.02640474325378521 1.0314614510697548e-07 6.986546998326339 -0.06948282334178335 S(ph)WGQQAQEYQEQK ddPTM_PC-9_AZD4547_30min_R2 3 SWGQQAQEYQEQK 13 0 Q5VZK9-2;Q5VZK9 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(1)WGQQAQEYQEQK;S(1)WGQQAQEYQEQK;S(1)WGQQAQEYQEQK 248.81 2.5475e-34 51068400.0 66307.0 79281.0 91770.0 136543.0 113976.0 108010.0 91922.0 109916.0 101759.0 94669.0 True False 87391.24672872176 104907.03282554519 90553.0698385473 105065.1209183206 98152.39976896753 101256.11762545773 100102.87992349039 92931.00781840665 107137.77299488419 91354.6671250008 0.9566150201077753 1.1483489144785637 0.9912254369516046 1.1500794017952007 1.0744103487856334 1.1083847252916894 1.0957609837986646 1.0172551741800882 1.1727673732124417 1.0 16.47919081465396 -4.742413528113849 24.859698040923316 1.0847441558855304 0.9566145644299544 0.281954776367092 0.06109948681169172 1517.805836150738 1983096.4512122471 0.013759376365436077 0.48986033237428483 1.809616185030298e-05 4.742413528113849 -0.128129591455576 S(ph)WGQQAQEYQEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SWGQQAQEYQEQK 13 0 Q5VZK9-2;Q5VZK9 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(1)WGQQAQEYQEQK;S(1)WGQQAQEYQEQK;S(1)WGQQAQEYQEQK;S(1)WGQQAQEYQEQK;S(1)WGQQAQEYQEQK 246.03 4.4122e-34 58971100.0 66892.3 72615.6 76045.8 87180.6 107816.0 88499.0 96891.2 98543.5 81021.0 83627.0 True False 78215.84520685207 79824.39686821832 77859.02027730255 82296.1536253187 86690.22876363172 83857.9566464145 87712.96410445888 95956.837540469 82205.77884832727 98787.91310903206 0.7917552132164728 0.8080380924751013 0.7881431829759343 0.8330589343909772 0.877538820644504 0.8488685913818284 0.8878916594548386 0.9713418830354438 0.8321440980092057 1.0 16.592046915647018 -1.5228787468896883 0.064148766437627 1.186054817475218 0.15561838352420695 0.698837426303268 0.03765412003317173 156.26215356178713 0.7482827326380075 2.2926112273395254 14.809531042236523 0.02999999988882999 1.5228787468896883 -1.030436433951011 S(ph)WGQQAQEYQEQK ddPTM_PC-9_Lapatinib_30min_R1 3 SWGQQAQEYQEQK 13 0 Q5VZK9-2;Q5VZK9 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(1)WGQQAQEYQEQK;S(1)WGQQAQEYQEQK;S(1)WGQQAQEYQEQK 203.05 1.1185999999999998e-09 49424200.0 96286.0 87702.0 89335.0 75347.8 102659.0 94836.0 99883.0 88997.0 106585.0 79312.0 True False 94912.94398330992 87498.93140739488 81990.22114307265 80889.12856489256 96620.79945535945 90780.08535351373 105054.45300872762 93132.12551952193 94580.27491019222 93020.97352340276 1.0203391814581597 0.9406365907940254 0.8814165025099965 0.8695794668773489 1.0386990782358456 0.9759098611312076 1.129363078341654 1.0011949132750282 1.0167629011794546 1.0 16.505268418208317 -6.278532997949654 24.68070678305394 1.029612875435917 0.9255691654598822 0.44664674872347376 0.05390639216186743 636.8888676114979 919572.9357784581 0.017239159882632443 0.019598452505634762 5.265832032729891e-07 6.278532997949654 -0.10404370997603485 S(ph)WHDVQVSSAYVK ddPTM_PC-9_AZD4547_30min_R2 4 SWHDVQVSSAYVK 13 0 A0A087WYR3;O43399;O43399-5;O43399-7 A0A087WYR3 TPD52L2 Tumor protein D54 1 S(1)WHDVQVSSAYVK;S(1)WHDVQVSSAYVK;S(1)WHDVQVSSAYVK;S(1)WHDVQVSSAYVK 128.06 0.00086463 22675000.0 70716.5 70133.0 105513.0 158077.0 117272.0 115210.0 96955.0 135343.0 106610.0 107775.0 True False 93202.87600542401 92802.12072443539 104113.82867903051 121634.78991530424 100990.80706206868 108005.9004872603 105583.8071732774 114428.84922273947 112245.18695137142 104001.83005415692 0.8961657305154191 0.8923123821581841 1.001076890904855 1.169544707549524 0.9710483652977999 1.038499999769411 1.0152110507891707 1.100258035489884 1.0792616523470975 1.0 16.666249389214983 -5.374710128945968 3.955690396459434 1.0537789931640775 0.894119880533495 0.5806943293622977 0.05313814650301666 0.15199206264629603 4.096716833456818 0.014081335685893094 0.03187901720267424 4.2197805987937494e-06 5.374710128945968 -0.15965911263058252 S(ph)WHDVQVSSAYVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SWHDVQVSSAYVK 13 0 A0A087WYR3;O43399;O43399-5;O43399-7 A0A087WYR3 TPD52L2 Tumor protein D54 1 S(1)WHDVQVSSAYVK;S(1)WHDVQVSSAYVK;S(1)WHDVQVSSAYVK 128.22 0.00010754 18703600.0 134981.4 170851.0 200041.0 221008.0 240081.0 219422.0 238320.0 225407.0 237932.0 196391.0 True False 157831.0850158272 187811.95816507662 204810.73609971724 208625.63827760398 193038.8514858784 207915.12404964538 215744.60431261727 219490.30508845844 241411.30537687996 231995.1336696989 0.6803206710384618 0.8095512832285193 0.8828234146984945 0.8992673034884988 0.8320814684014701 0.8962046779207997 0.9299531455680524 0.9460987461959263 1.040587798365578 1.0 17.82373501813352 -2.7158262207559476 0.23176904292946285 1.0155819198194818 2.632542511888352e-17 0.8107101506851215 0.04206055752869766 13.835851440004781 0.2934523422924169 0.06762104830650374 4.766499386205741 0.0019238613916898388 2.7158262207559476 -1.0155819198194818 S(ph)WHDVQVSSAYVK ddPTM_PC-9_Lapatinib_30min_R1 3 SWHDVQVSSAYVK 13 0 A0A087WYR3;O43399;O43399-5;O43399-7 A0A087WYR3 TPD52L2 Tumor protein D54 1 S(1)WHDVQVSSAYVK;S(1)WHDVQVSSAYVK;S(1)WHDVQVSSAYVK 157.37 0.0001579 24064400.0 117901.0 87461.0 101820.0 71011.6 108235.0 113146.0 120707.0 120737.0 120906.0 89985.0 True False 116219.71011960445 87258.48942808788 93448.75263656605 76234.02995175323 101868.83009819733 108307.0093362083 126956.61783611302 126346.88179208853 107288.2930833767 105538.78735252432 1.1012037662646563 0.826790714740961 0.8854446311233923 0.7223318730876988 0.9652264598979287 1.0262294276173316 1.2029380005291146 1.1971606360234204 1.0165768981692827 1.0 16.687413786516615 -6.788969759118593 2.64680689702649 1.1184250827576208 0.8788592239630462 0.43803974307560056 0.10924692223360861 0.2316996445689082 3.3244299131245927 0.04117260213041708 0.03754284348230989 1.6256619502319326e-07 6.788969759118593 -0.2395658587945746 S(ph)WHLTPSCPLDPAPLR ddPTM_PC-9_AZD4547_30min_R2 1 SWHLTPSCPLDPAPLR 16 0 D3YTB5;P51617-4;P51617-2;P51617-3;P51617;H7C3C1;H7C2I6;H7C224 D3YTB5 IRAK1 Interleukin-1 receptor-associated kinase 1 1 S(1)WHLTPSCPLDPAPLR 61.757 0.022772 2337000.0 3948.0 3042.4 4603.7 7672.5 6098.9 5960.2 3746.2 7079.6 5986.0 5319.0 True False 5203.381876498606 4025.79630262533 4542.651929995855 5903.72366394334 5252.173009677078 5587.507751793834 4079.604542648976 5985.610493023692 6302.407739338797 5132.7834289776 1.013754417753618 0.7843300537282223 0.8850270019868551 1.150199252634219 1.0232602022570159 1.0885921506543694 0.794813301417939 1.1661529413517386 1.2278733023797528 1.0 12.32552567388161 -5.740694314683119 24.435222651964736 1.0593954874192981 0.8833662733348122 0.2856100155708281 0.12269027015666932 240.8165361189527 283650.21519034536 0.03390386049512011 0.05863100782213452 1.8167939931786727e-06 5.740694314683119 -0.1760292140844859 S(ph)WHLTPSCPLDPAPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SWHLTPSCPLDPAPLR 16 0 D3YTB5;P51617-4;P51617-2;P51617-3;P51617;H7C3C1;H7C2I6;H7C224 D3YTB5 IRAK1 Interleukin-1 receptor-associated kinase 1 1 S(1)WHLTPSCPLDPAPLR 82.755 0.0034549 1687300.0 4214.7 4620.7 4978.4 5136.8 7174.7 5801.8 7683.7 7816.7 6379.7 3559.0 True False 4928.165465880528 5079.412558857547 5097.103936687136 4849.001749730301 5768.869039014893 5497.5433945148225 6955.844310829373 7611.519907478254 6472.991043293374 4204.218526971501 1.1721953638386444 1.2081704426806972 1.2123784489287295 1.153365772645331 1.3721620324932264 1.307625509769818 1.6544916174564313 1.8104482102078538 1.5396419100879082 1.0 12.037621944348583 -6.885025150081763 1.8730566636054309 1.5607207383046937 1.201816730118751 0.26599576786672674 0.20531942498505207 0.3609851985771278 2.5935290395477413 0.08562811154675361 0.07166127355733895 1.303091313984257e-07 6.885025150081763 -0.3589040081859427 S(ph)WHLTPSCPLDPAPLR ddPTM_PC-9_Lapatinib_30min_R1 1 SWHLTPSCPLDPAPLR 16 0 D3YTB5;P51617-4;P51617-2;P51617-3;P51617;H7C3C1;H7C2I6;H7C224 D3YTB5 IRAK1 Interleukin-1 receptor-associated kinase 1 1 S(0.987)WHLT(0.013)PSCPLDPAPLR 57.173 0.033216 1886500.0 1321.5 2502.6 3347.1 1151.1 2868.2 4848.7 2307.2 2063.1 3704.7 1064.3 True False 1302.655167666581 2496.805383459285 3071.914358179634 1235.755733957033 2699.4981150981625 4641.332403871755 2426.655526783699 2158.9591577168376 3287.43767377951 1248.2628369093927 1.0435744213068618 2.000224079121984 2.4609515458983533 0.9899803930850603 2.1626039286581036 3.718233265169821 1.9440260937287215 1.7295709636459755 2.633610147297956 1.0 10.285706027821416 -4.770414697895872 4.406054591192988 2.1298704576639276 0.956947753342365 0.14175491901085235 0.7522693773452256 0.39570029669615053 16.45110719863546 0.18973456826099017 1.464783784861262 1.6966228123044336e-05 4.770414697895872 -1.1729227043215626 S(ph)WITIPR ddPTM_PC-9_AZD4547_30min_R2 3 SWITIPR 7 0 H0Y8J2;Q03188;Q03188-2 H0Y8J2 CENPC Centromere protein C 1 S(1)WITIPR;S(1)WITIPR;S(1)WITIPR 124.08 0.0046531 7616000.0 27171.800000000003 29996.7 32455.899999999998 35991.2 37412.0 41925.7 36911.1 38965.7 32578.6 35946.9 True False 35811.867191450074 39692.54665756026 32025.513559691644 27693.984898496918 32217.989578127017 39304.07935126049 40196.11639372449 32944.446407708536 34300.63828546991 34688.409972384805 1.0323871062397973 1.1442596155072895 0.923233828970164 0.7983642063889322 0.9287825415974825 1.1330608518104515 1.158776560405171 0.9497248917991736 0.9888212896692701 1.0 15.08216609225422 -6.739542814118834 24.995694756307003 1.0499783107764697 0.9637188613715248 0.13628104953274722 0.10126232966038691 543.5084866001641 620432.2858216398 0.03773304144591102 0.037704625973281655 1.821617483446873e-07 6.739542814118834 -0.0862594494049449 S(ph)WITIPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SWITIPR 7 0 H0Y8J2;Q03188;Q03188-2 H0Y8J2 CENPC Centromere protein C 1 S(1)WITIPR;S(1)WITIPR 101.25 0.011258 4220600.0 13769.5 13900.7 15877.8 15035.8 20540.0 15411.400000000001 16503.5 14419.0 15546.0 11092.9 True False 16100.404389978397 15280.669629474145 16256.386968891828 14193.39287272131 16515.334447623714 14603.199053780847 14940.169005007045 14040.51652819335 15773.330839857477 13103.954958651912 1.2286675618758958 1.1661112753890424 1.2405710352475317 1.0831380997192832 1.2603320524021973 1.1144115726786024 1.1401267061852016 1.0714716719110111 1.2037076508297295 1.0 13.677714682770343 -14.522878744288478 0.10126649855877438 0.4723706960380288 1.2743311452776587 0.45226118297194984 0.059301275271002866 160.75499303243163 1.1003705601762204 17.836363987414884 0.9023293277942793 3.0000000068515207e-15 14.522878744288478 0.80196044923963 S(ph)WITIPR ddPTM_PC-9_Lapatinib_30min_R1 2 SWITIPR 7 0 H0Y8J2;Q03188;Q03188-2 H0Y8J2 CENPC Centromere protein C 1 S(1)WITIPR;S(1)WITIPR 101.25 0.011258 5727200.0 18115.6 15852.8 19214.1 14496.3 18078.9 19775.2 16233.5 17555.2 19018.8 13333.8 True False 17857.268222005838 15816.093815593122 17634.39086657086 15562.406260239188 17015.53464648496 18929.460794242732 17073.991198874464 18370.87868040843 16876.70246715733 15638.529563828297 1.1418764244503814 1.0113542805313058 1.1276246142322077 0.9951323234528916 1.0880520816894228 1.2104373826824686 1.091790064352749 1.1747190556137719 1.0791745092321794 1.0 13.932817247009087 -6.53114175410311 24.925574974489187 1.1240756438914716 1.0656328804879605 0.06324399240309553 0.06785933173038408 352.4537329306934 1063177.5008676343 0.020739701038611596 0.02077034862468972 2.943460728801238e-07 6.53114175410311 -0.05844276340351118 S(ph)WLIISLGLY(ph)S(ph)QVS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 SWLIISLGLYSQVSK 15 0 O43155 O43155 FLRT2 Leucine-rich repeat transmembrane protein FLRT2 4 S(0.984)WLIIS(0.038)LGLY(0.989)S(0.99)QVS(0.999)K 41.621 0.045859 1473900.0 3781.3 2420.2 6331.5 16218.0 10981.0 7500.0 4067.5 6108.0 3259.4 6337.5 True False 4983.674744074008 3202.4823204094887 6247.540173071395 12479.190665602237 9456.477695857293 7031.023814377665 4429.4996202084 5164.148947876818 3431.685229803017 6115.626053984869 0.8149083511779968 0.5236556800791947 1.0215700106452015 2.040541811327876 1.546281216735867 1.149681774574221 0.7242920971798449 0.8444186911186173 0.5611339214514223 1.0 12.57828447903983 -7.22076330395512 5.8405600031382425 0.7690775963860982 1.203337956241083 0.19583253909732445 0.39628784280713264 0.37499246861895374 35.113126630960075 0.17806382064185935 0.13482200130795238 6.015014741581458e-08 7.22076330395512 0.4342603598549849 S(ph)WLIISLGLY(ph)S(ph)QVS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SWLIISLGLYSQVSK 15 0 O43155 O43155 FLRT2 Leucine-rich repeat transmembrane protein FLRT2 4 S(0.639)WLIIS(0.361)LGLY(1)S(1)QVS(1)K;S(0.999)WLIIS(0.041)LGLY(0.981)S(0.984)QVS(0.996)K 55.011 0.024919999999999998 408698000.0 26369.0 42483.1 56092.8 84441.7 49967.5 77130.0 58553.0 47550.9 81256.2 55988.6 True False 30832.750888510145 46700.54140697324 57430.26508512863 79710.7053126852 40176.72706970004 73085.16702039515 53006.43595299042 46302.73925934317 82444.4182033725 66138.88997448636 0.46618186214501245 0.7060980525223265 0.868328227269657 1.2052017405105269 0.6074599541237925 1.1050256066980921 0.8014412696287782 0.7000834044418472 1.2465346520810394 1.0 16.01321121217037 -4.973047441961028 2.1314435497183055 0.9304730704185727 0.4325908534445304 0.3735098165663294 0.19687903689582362 0.4840042011079597 3.376739732845728 0.05099268448925807 0.40133165369428997 1.0640267784922178e-05 4.973047441961028 -0.49788221697404234 S(ph)WPASPR ddPTM_PC-9_AZD4547_30min_R2 1 SWPASPR 7 0 Q86YD1 Q86YD1 PTOV1 Prostate tumor-overexpressed gene 1 protein 1 S(1)WPASPR 90.601 0.018039 0.0 12433.0 12950.0 19611.0 22958.0 25929.0 19499.0 18810.0 22616.0 14695.0 18688.0 True False 16386.435377534737 17135.83424894755 19350.945326400233 17665.387797564188 22329.205917118987 18279.72444754003 20484.05356020161 19121.216863978738 15471.747699562902 18033.738808184502 0.9086543590227587 0.9502097391568385 1.073041233003659 0.9795743403773187 1.2381906023272897 1.013640301768366 1.1358739182196123 1.0603024180044511 0.8579334470864768 1.0 14.138410911141783 -5.13247486710527 3.458123841923136 1.0538624906617464 0.9144741643007387 0.19108676582610107 0.09477858916975103 0.37042382597165024 7.9198265381063235 0.024463483980118852 0.08208173397349253 7.37097830418581e-06 5.13247486710527 -0.13938832636100773 S(ph)WPASPR ddPTM_PC-9_Lapatinib_30min_R1 1 SWPASPR 7 0 Q86YD1 Q86YD1 PTOV1 Prostate tumor-overexpressed gene 1 protein 1 S(1)WPASPR 90.601 0.015819 3552100.0 20738.0 19553.0 28598.0 22594.0 21332.0 23465.0 18341.0 16664.0 21083.0 15564.0 True False 20442.272317116563 19507.726229832744 26246.782831472377 24255.638131374515 20077.29370032565 22461.456649586617 19290.607236797758 17438.270274922877 18708.410526167692 18254.216662273597 1.119865765555696 1.0686695896488292 1.4378476664910633 1.3287690499206242 1.0998715569000475 1.2304804454309024 1.056775406674453 0.9553009366303264 1.0248815861177318 1.0 14.155942139710849 -7.375504511514985 3.0585462544736304 0.9924686131287809 1.2191603396395456 0.4840438842854682 0.10481496565295145 0.2498563436354747 4.460834549992595 0.05331980932977239 0.033604389052492294 4.212069111719649e-08 7.375504511514985 0.22669172651076475 S(ph)WQGDGSPMANGAGAVVHHQR ddPTM_PC-9_AZD4547_30min_R2 1 SWQGDGSPMANGAGAVVHHQR 21 0 Q9H201;I6L9I8 Q9H201 EPN3 Epsin-3 1 S(0.614)WQGDGS(0.386)PMANGAGAVVHHQR 64.679 0.0031536 5044500.0 4456.1 8502.4 12980.0 16588.0 11443.0 8511.1 11428.0 12622.0 7363.3 10952.0 True False 5873.047107362071 11250.634526505926 12807.87671901866 12763.892882045247 9854.336970557786 7978.899571539971 12445.069861030512 10671.559924705502 7752.50900552512 10568.573813529361 0.5557085762928285 1.0645366844203166 1.21188316843874 1.207721411351222 0.932418805453462 0.7549646444561688 1.1775543304716247 1.0097445609022764 0.7335435359878686 1.0 13.367493083519665 S(ph)WRPAGPSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SWRPAGPSPR 10 1 K7EJX8 K7EJX8 DUS3L 1 S(1)WRPAGPSPR 68.626 0.019109 13796000.0 2397.8 3163.3 3919.7 3235.0 3982.7 2885.2 3714.2 3755.1 3533.2 2230.3 True False 2803.700181291275 3477.3315184786056 4013.16051354503 3053.753438011507 3202.3185250511674 2733.895032895682 3362.364087520657 3656.5326038573303 3584.866365842303 2634.635734954916 1.0641699511220104 1.3198528632794506 1.5232316408301139 1.1590799431951693 1.2154691757059788 1.0376747709840293 1.2762159272762592 1.3878702681150343 1.3606686944537503 1.0 11.363387793127272 -11.82353573647704 1.927596219121637 7.083987832739549e-05 1.263296911591253 0.23400759377704183 0.1412929619990983 5191259.387655419 608181.782554091 22619565.017495617 0.038205662334870674 1.5012888651964746e-12 11.82353573647704 1.2632260717129256 S(ph)WRPAGPSPR ddPTM_PC-9_Lapatinib_30min_R1 1 SWRPAGPSPR 10 1 K7EJX8 K7EJX8 DUS3L 1 S(1)WRPAGPSPR 69.27600000000001 0.01831 2327000.0 0.0 579.57 991.22 963.95 0.0 684.66 732.82 688.12 660.33 617.97 True False 0.0 578.2280412736746 909.725717819849 1034.8420986429337 0.0 655.3786878204127 770.7618338842015 720.0925673055649 585.9566818168339 724.7852911067347 0.0 0.7977921853115015 1.2551658111476207 1.4277912525828822 0.0 0.9042383942693714 1.0634347072734622 0.9935253600497271 0.8084555371178795 1.0 9.501409867202616 -4.794109722616684 4.830408487154234 0.9248307902079898 9.793811197135586e-16 0.37782822102306934 0.35563505666703915 0.1867639940739025 9.719414868441822 0.0916792761302182 0.5348300488329254 1.606535317558026e-05 4.794109722616684 -0.9248307902079888 S(ph)WSLATFR ddPTM_PC-9_AZD4547_30min_R2 1 SWSLATFR 8 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 S(0.835)WS(0.165)LATFR 111.46 0.0037457000000000002 3641400.0 15929.0 17146.0 25766.0 32769.0 28923.0 22719.0 21962.0 26605.0 22494.0 24051.0 True False 20994.090656217395 22688.109191695345 25424.326004794675 25214.613326003182 24907.54069732087 21298.37733851283 23916.575453968526 22493.808572079703 23682.98691758886 23208.981810554644 0.9045675000990353 0.9775572826455307 1.095452019925862 1.0864161785217328 1.073185411606199 0.9176782295907123 1.0304879227012058 0.9691854970496937 1.0204233477755864 1.0 14.502395611879216 -9.664022391678719 15.431349054901986 0.999999997077525 1.0110241974055179 0.0 0.06329313908539061 0.0 0.0 0.06476106900023174 0.015706866347992295 2.1675923435963225e-10 9.664022391678719 0.011024200327992895 S(ph)WSLATFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SWSLATFR 8 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 S(0.72)WS(0.28)LATFR 93.178 0.0074197 2028000.0 13970.0 10329.0 15072.0 13711.0 13303.0 14005.0 14447.0 15367.0 11464.0 10306.0 True False 16334.845079922883 11354.394858017109 15431.373640878313 12942.81712166176 10696.372646384536 13270.553145606553 13078.475572777701 14963.632532682368 11631.639312242782 12174.396217748894 1.3417375932047064 0.9326454187078029 1.2675268132296462 1.0631177834341052 0.878595739375595 1.0900378883890427 1.0742607139490632 1.2291067470653767 0.9554181664701503 1.0 13.571562603991827 -4.743214063069974 24.76363392242888 1.0648366823208484 1.3417385821127343 0.34828746734386307 0.1171030610767699 1256.622094077662 1707332.6594348792 0.02865069887974528 0.9154944958912985 1.8062835922038513e-05 4.743214063069974 0.27690189979188595 S(ph)WSPPPEVSR ddPTM_PC-9_AZD4547_30min_R2 3 SWSPPPEVSR 10 0 Q9NR19;Q9NR19-2;F8WCJ4;C9JXD9;C9IYL0;B4DEH9;C9JY31 Q9NR19 ACSS2 Acetyl-coenzyme A synthetase, cytoplasmic 1 S(0.826)WS(0.174)PPPEVSR;S(0.993)WS(0.007)PPPEVSR;S(0.608)WS(0.392)PPPEVSR 138.76 0.00011981 117664000.0 131563.0 117841.0 175245.0 233008.0 208290.0 184075.0 150615.0 202291.0 151913.0 156894.0 True False 173397.29731960132 155930.7987436469 172921.1367969512 179291.60553771406 179372.52884710964 172564.7611508756 164019.44322008285 171031.57413473347 159942.81104346368 151401.188814817 1.145283591740408 1.029917928414487 1.1421385667483488 1.184215308619608 1.1847498044847269 1.139784717027185 1.083343165955583 1.1296580659213116 1.0564171410773675 1.0 17.208017007967243 -8.499684876105349 1.1449450233865683 0.9992839215759294 1.1336356084018815 0.4929992404107367 0.043159051640544004 0.4833644086419452 1.3904763344345747 0.044650650896768576 0.014210502645079316 3.1645730401803017e-09 8.499684876105349 0.1343516868259521 S(ph)WSPPPEVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SWSPPPEVSR 10 0 Q9NR19;Q9NR19-2;F8WCJ4;C9JXD9;C9IYL0;B4DEH9;C9JY31 Q9NR19 ACSS2 Acetyl-coenzyme A synthetase, cytoplasmic 1 S(0.746)WS(0.254)PPPEVSR;S(0.942)WS(0.058)PPPEVSR;S(0.964)WS(0.036)PPPEVSR 129.0 0.00026087 66631600.0 227848.0 239499.0 237853.0 250945.0 266461.0 235759.0 238602.0 216872.0 226030.0 191544.0 True False 266418.16619687027 263274.87792624993 243524.31758252627 236885.36522466704 214249.8798562933 223395.38301000022 215999.89123111436 211179.33979487786 229335.26114325091 226269.41093853037 1.1774378387772748 1.16354604378129 1.0762582382321377 1.0469173196770316 0.9468795581674875 0.987298203868525 0.9546137515238157 0.9333092746338922 1.0135495566634654 1.0 17.78768203619523 -5.607502250868978 1.2473889587594809 0.9679919401462278 1.1874015716944806 0.8958433682838847 0.026403772025454356 0.14623995913728732 0.42435878514503095 0.008635318532017206 0.02820845041676354 2.468867309184711e-06 5.607502250868978 0.21940963154825277 S(ph)WSPPPEVSR ddPTM_PC-9_Lapatinib_30min_R1 1 SWSPPPEVSR 10 0 Q9NR19;Q9NR19-2;F8WCJ4;C9JXD9;C9IYL0;B4DEH9;C9JY31 Q9NR19 ACSS2 Acetyl-coenzyme A synthetase, cytoplasmic 1 S(0.987)WS(0.013)PPPEVSR 138.25 0.00011882 18118000.0 81729.0 70508.0 85807.0 59700.0 68610.0 79977.0 63860.0 73443.0 84735.0 55719.0 True False 80563.529472737 70344.74305799873 78752.27968459863 64090.53715336184 64574.494692449945 76556.57014549279 67166.35833062019 76855.42989685312 75191.25200089261 65349.954909099346 1.2328016076644501 1.0764313939595986 1.2050854479416502 0.9807281006162998 0.9881337298896679 1.1714861969221195 1.0277950218029597 1.176059417389923 1.150593785496598 1.0 15.995898620123468 -2.150934386919084 1.2521719647955867 1.0857433867803017 134.30941323199326 0.2206975858295266 0.08121338233874618 2127.7578255184817 4.820609929034293 0.02362366214882136 813107.3745170333 0.007064242725698757 2.150934386919084 133.22366984521295 S(ph)WSSEEESNQATGTSR ddPTM_PC-9_AZD4547_30min_R2 2 SWSSEEESNQATGTSR 16 0 F6UZG9;Q8NFZ0;Q8NFZ0-2 F6UZG9 FBXO18 F-box only protein 18 1 S(1)WSSEEESNQATGTSR;S(0.999)WS(0.001)SEEESNQATGTSR 184.92 1.0570999999999999e-30 7714300.0 19017.8 15365.0 19366.4 20724.9 19188.2 20070.5 13523.1 23521.0 19341.0 16606.2 True False 25065.064805186208 20331.435771048597 19109.58888221902 15947.094501513116 16524.249642441377 18815.48846219559 14726.629702284019 19886.369908809873 20363.325774565932 16024.821992533894 1.5641399833872878 1.268746434782314 1.192499292105856 0.9951495566654661 1.0311658781695154 1.1741464879274097 0.9189886607879504 1.2409729055383647 1.2707364727079893 1.0 13.968020710688945 -4.72607068448735 1.4840109598122744 1.0965956976268219 1.7900227023585704 0.6338021749584639 0.10865154136817447 0.86959017788563 1.6162602170220024 0.03187817848189609 0.9303065402672165 1.8790109696380815e-05 4.72607068448735 0.6934270047317486 S(ph)WSSEEESNQATGTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SWSSEEESNQATGTSR 16 0 F6UZG9;Q8NFZ0;Q8NFZ0-2 F6UZG9 FBXO18 F-box only protein 18 1 S(0.931)WS(0.066)S(0.003)EEESNQATGTSR 117.13 0.00014771 5465500.0 8909.0 12890.0 13534.0 11113.0 13058.0 10145.0 9913.9 12255.0 13728.0 10830.0 True False 10417.117739229281 14169.634012957737 13856.701887980827 10490.37463883212 10499.378637637326 9612.978340748192 8974.783621579623 11933.319235245823 13928.746029175574 12793.393269767175 0.8142576030900721 1.1075743326395537 1.0831138850961786 0.8199837539288771 0.8206875546028144 0.7514017694949775 0.7015170590267451 0.9327720162754752 1.0887452402554856 1.0 13.643111349334488 -5.7692677270412345 24.98990375646496 0.8563208464483071 1.0122411855320383 0.15740752945160819 0.13091249087348625 266.60964071895415 851082.0078901816 0.03839019562086714 0.05815252049732608 1.7011095118192496e-06 5.7692677270412345 0.15592033908373126 S(ph)WSSEEESNQATGTSR ddPTM_PC-9_Lapatinib_30min_R1 2 SWSSEEESNQATGTSR 16 0 F6UZG9;Q8NFZ0;Q8NFZ0-2 F6UZG9 FBXO18 F-box only protein 18 1 S(0.997)WS(0.003)SEEESNQATGTSR;S(0.998)WS(0.002)SEEESNQATGTSR 169.15 1.3663e-05 10225800.0 13615.099999999999 14340.0 14517.2 12599.3 16615.1 14686.1 17783.1 16748.9 15642.0 13146.0 True False 13420.946177296451 14306.796611046977 13323.651854012545 13525.894552032702 15637.832484543442 14058.009737971197 18703.82190462344 17527.115038865566 13880.233242437746 15418.268584056064 0.8704574125252279 0.9279120111995939 0.8641470850877803 0.8772641673929422 1.0142405030299204 0.9117761609438103 1.2130948298543032 1.1367758281880138 0.9002459106719161 1.0 13.912353144449371 -6.698723845264037 1.6184352378219777 1.064935425870717 0.8895000044241661 0.3788356487910667 0.08968245505460486 0.37372219313491306 2.0281133628642416 0.03823305244930812 0.03655103039384173 2.0011339257447535e-07 6.698723845264037 -0.175435421446551 S(ph)WSSTPTAGGIEGSVK ddPTM_PC-9_AZD4547_30min_R2 2 SWSSTPTAGGIEGSVK 16 0 B5MCH3;Q8N3C7 B5MCH3 CLIP4 CAP-Gly domain-containing linker protein 4 1 S(0.978)WS(0.011)S(0.011)T(0.001)PTAGGIEGSVK;S(0.996)WS(0.003)S(0.001)TPTAGGIEGSVK 125.33 3.214e-05 15758000.0 27268.0 23798.0 37661.0 54140.0 45617.0 46511.0 37474.0 50329.0 36816.0 41288.0 True False 35938.65679036578 31490.238104745476 37161.590532739756 41658.85945466176 39283.86695673635 43602.65981740264 40809.11340324272 42551.80949536546 38762.01859864635 39842.51968708912 0.9020176703837237 0.7903676361851637 0.9327118571966693 1.0455879744011576 0.9859784789029343 1.0943750586018277 1.0242603561156505 1.067999961587627 0.9728807039080686 1.0 15.282021267545815 -5.557903925827361 3.661773390546367 1.0307186178190404 0.8468262009581153 0.7408635850193157 0.04314202598596253 0.0967590358337422 2.741287402801675 0.01124030861735104 0.021997570313514698 2.7675538130674865e-06 5.557903925827361 -0.18389241686092506 S(ph)WSSTPTAGGIEGSVK ddPTM_PC-9_Lapatinib_30min_R1 2 SWSSTPTAGGIEGSVK 16 0 B5MCH3;Q8N3C7 B5MCH3 CLIP4 CAP-Gly domain-containing linker protein 4 1 S(0.994)WS(0.006)STPTAGGIEGSVK;S(0.988)WS(0.012)STPTAGGIEGSVK 226.65 1.0158e-28 15375200.0 47936.0 41017.0 50057.0 40403.0 44981.0 47040.0 41345.0 35194.0 43409.0 41335.0 True False 47252.4238496142 40922.02765657696 45941.50668560787 43374.37140045692 42335.30601604853 45028.20885559579 43485.64179736132 36829.24172201366 38519.82130296509 48479.69967457462 0.9746847477769325 0.8441064596371394 0.9476442097206738 0.894691421184789 0.8732584215708634 0.9288054414085205 0.8969866168574379 0.7596837845373228 0.7945556915891326 1.0 15.565093141080117 -7.554975577571023 24.92625181523342 0.8319387868958317 0.9072943754928079 0.11065348060922986 0.06841428448303188 293.2488057101842 227732.3753427178 0.030108238251730944 0.017383149968440446 2.7862778497814943e-08 7.554975577571023 0.07535558859697622 S(ph)WSTATSPLGGERPFR ddPTM_PC-9_AZD4547_30min_R2 1 SWSTATSPLGGERPFR 16 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;Q9UPQ0-2;Q9UPQ0;D6RD46;D6RJ93;Q6NVB9;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 S(0.727)WS(0.115)T(0.115)AT(0.043)S(0.001)PLGGERPFR 57.93600000000001 0.026206999999999998 7641800.0 9024.4 6644.8 8352.4 11983.0 11538.0 7091.1 7505.4 11826.0 5578.3 10625.0 True False 11893.971480819157 8792.601653853802 8241.641718638784 9220.504485504474 9936.147860377147 6647.6923960178 8173.366060113622 9998.563434445196 5873.157549674844 10253.02198399831 1.1600454480037052 0.8575619624707959 0.8038256166329647 0.8992962757609156 0.9690945631331229 0.6483641999785744 0.79716654005713 0.975182092660072 0.5728220966307266 1.0 13.323761573061555 -4.762155213018616 4.677312755650418 0.8315176854888907 1.1849793985512478 0.3520061772361903 0.13227562367287116 0.20935457821770048 10.744983515708777 0.03152256715906785 0.24758596906129332 1.7291982485605036e-05 4.762155213018616 0.3534617130623571 S(ph)Y(ph)IKSNLELYQQYT(ph)AMAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SYIKSNLELYQQYTAMAPK 19 1 Q8ND61 Q8ND61 C3orf20 Uncharacterized protein C3orf20 3 S(0.917)Y(0.906)IKS(0.175)NLELY(0.113)QQY(0.41)T(0.478)AMAPK 43.261 0.04431 3909000.0 3329.8 3899.8 4267.6 4117.5 4202.7 3248.4 3358.6 3775.6 3014.0 4157.9 True False 3893.469373452201 4286.946371119671 4369.355768963127 3886.8098241151097 3379.211104334385 3078.048185518624 3040.4490938417093 3676.4945005788727 3058.0740480722015 4911.694356081711 0.7926937409350945 0.8728039776765689 0.8895821792235393 0.7913378851235768 0.6879929530122758 0.6266774685821712 0.6190224540492821 0.748518583210822 0.6226108194793641 1.0 12.2620050724295 -6.08324201790364 3.496404786499803 0.6958129661471023 0.853080071685353 0.2233621706590614 0.10820153089592748 0.29372701106727517 6.831607819937749 0.030954240036298847 0.0424484119906168 8.255777542758605e-07 6.08324201790364 0.15726710553825074 S(ph)YAKFSAT(ph)PRYMT(ph)Y(ph)N ddPTM_PC-9_Lapatinib_30min_R1 1 SYAKFSATPRYMTYN 15 2 P35998;P35998-2 P35998 PSMC2 26S protease regulatory subunit 7 4 S(0.534)Y(0.465)AKFS(0.432)AT(0.569)PRY(0.514)MT(0.577)Y(0.908)N 43.813 0.045482 0.0 7050.6 4291.0 6748.4 6403.9 6040.2 6696.7 4340.5 4001.0 3914.3 4997.1 True False 6950.0571510783175 4281.064453138253 6193.5726015773225 6874.864168784153 5684.927311490106 6410.2977517701565 4565.2298517703875 4186.901066368605 3473.4303145936633 5860.842076782792 1.185846173642923 0.7304521085967001 1.0567717949802151 1.1730164503183458 0.9699847286468345 1.0937502952287326 0.7789375301298669 0.7143855800098493 0.5926503852327553 1.0 12.516892248408551 -7.334256522229839 5.5912388166605 0.7432252430096317 1.0251860906551171 0.4118010777259493 0.15277926248669985 0.21715746922620074 12.396950732687298 0.06368923979230219 0.04261596403482178 4.6317325903201335e-08 7.334256522229839 0.28196084764548546 S(ph)YDNLTTACDNTVPLASR ddPTM_PC-9_AZD4547_30min_R2 2 SYDNLTTACDNTVPLASR 18 0 G5E953;Q13615-3;Q13615-2;Q13615 G5E953 MTMR3 Myotubularin-related protein 3 1 S(0.993)YDNLT(0.006)TACDNTVPLASR;S(1)YDNLTTACDNTVPLASR 156.29 1.4173e-05 56845000.0 46059.0 56069.0 48648.0 69809.0 62174.0 63466.0 55533.0 64706.0 49276.0 58926.0 True False 60704.803913285046 74192.20776094508 48002.8957339615 53715.613588298496 53542.21330135972 59497.46098710574 60475.32941832411 54707.174495958985 51880.62876105222 56863.01867567847 1.067562104986343 1.3047532383763276 0.8441847944751018 0.9446493492487379 0.941599910598149 1.0463296246450258 1.0635265384563677 0.9620870606251936 0.912379081683236 1.0 15.795203068660424 -5.2606168770871164 24.99912230391189 0.967945056240622 1.1861576686068265 0.5508138640768034 0.0800703316525262 52.17862554254781 1585848.8365419016 0.020787105359304482 0.04883667551111076 5.487608535204109e-06 5.2606168770871164 0.21821261236620448 S(ph)YDNLTTACDNTVPLASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SYDNLTTACDNTVPLASR 18 0 G5E953;Q13615-3;Q13615-2;Q13615 G5E953 MTMR3 Myotubularin-related protein 3 1 S(1)YDNLTTACDNTVPLASR;S(0.991)Y(0.001)DNLTT(0.001)ACDNT(0.007)VPLASR;S(0.999)YDNLT(0.001)TACDNTVPLASR;S(0.988)YDNLT(0.006)T(0.006)ACDNTVPLASR 289.68 3.798299999999999e-106 42617700.0 23239.799999999996 33316.6 39039.5 28903.1 40710.1 24930.100000000002 34984.1 25416.399999999998 20242.3 17561.1 True False 27173.839133027344 36624.05186626126 39970.349738128236 27283.75301211451 32733.248144898098 23622.721669067185 31670.15278504964 24749.246430901807 20538.305342830772 20744.78841640889 1.3099116070778118 1.7654579613495625 1.9267658428616292 1.3152099922375382 1.5779022416544135 1.138730422065037 1.5266558592614476 1.1930344110584148 0.9900465085768341 1.0 14.340461322266156 -7.3829090895089236 0.555333016135004 0.9736793086430465 1.6538187386379837 0.5138276976206919 0.2099470168035518 0.6953710673991857 0.4487021108751061 0.19976960972020377 0.14893778995924237 4.140863460873567e-08 7.3829090895089236 0.6801394299949372 S(ph)YDNLTTACDNTVPLASR ddPTM_PC-9_Lapatinib_30min_R1 4 SYDNLTTACDNTVPLASR 18 0 G5E953;Q13615-3;Q13615-2;Q13615 G5E953 MTMR3 Myotubularin-related protein 3 1 S(1)YDNLTTACDNTVPLASR;S(1)YDNLTTACDNTVPLASR;S(0.999)YDNLT(0.001)TACDNTVPLASR;S(0.987)YDNLT(0.013)TACDNTVPLASR 195.86 1.6115e-14 56536900.0 64458.0 88452.2 56797.5 80114.6 87923.0 80037.5 71173.3 76975.2 84282.6 50370.100000000006 True False 63538.81709985051 88247.39436538698 52127.828794690315 86006.49493847114 82751.5420032688 76614.48270152527 74858.30522036852 80551.74880378306 74789.80605287582 59076.50467106064 1.0755344693061333 1.4937815779174908 0.8823783513418623 1.4558494179260826 1.4007521681255741 1.2968689181615687 1.2671417450504445 1.3635158215994172 1.2659822457220042 1.0 15.850296849475738 -4.505956696839011 16.39626388612692 1.279844331990098 0.688505751787523 0.08945964887115943 0.18311252444793055 1069020.8351406453 24764775.60224212 0.04283330161744012 15246920.067591388 3.1192005816241195e-05 4.505956696839011 -0.591338580202575 S(ph)YDSSMESR ddPTM_PC-9_AZD4547_30min_R2 2 SYDSSMESR 9 0 Q9HCG8;B7WP74 Q9HCG8 CWC22 Pre-mRNA-splicing factor CWC22 homolog 1 S(0.996)YDS(0.001)S(0.001)MES(0.001)R;S(0.892)YDS(0.054)S(0.054)MESR 84.31 0.013306 31398000.0 68866.0 74820.0 96921.0 137847.0 155740.0 114880.0 87612.0 117733.0 101814.0 115454.0 True False 90763.95549821528 99004.1018151549 95635.76421294364 106068.50386491982 134118.18926808253 107696.53543942736 95409.29827306686 99540.07008519689 107195.68018259942 111411.99060146257 0.8146695432710791 0.8886305798924952 0.858397410338418 0.952038495069555 1.203803904265955 0.9666512092461758 0.8563647212296946 0.8934412673880558 0.9621556854329483 1.0 16.7655449840479 -5.803893053571769 5.095614223649953 0.9770998961551426 0.8567038046824804 0.29322271102083775 0.08765293508242678 0.2824165083530423 16.743641337123282 0.02765381965267563 0.043111726554892836 1.5707495588978181e-06 5.803893053571769 -0.12039609147266217 S(ph)YDSSMESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SYDSSMESR 9 0 Q9HCG8;B7WP74 Q9HCG8 CWC22 Pre-mRNA-splicing factor CWC22 homolog 1 S(1)YDSSMESR 86.189 0.011855 5569000.0 23162.0 21561.0 34932.0 35429.0 25285.0 32098.0 37179.0 30637.0 28714.0 37327.0 True False 27082.869129647363 23701.433588315107 35764.91136034771 33444.02799236778 20330.58575989124 30414.724374700385 33657.13596734977 29832.81121258475 29133.887928448974 44094.08961963056 0.6142063338482023 0.5375195132220917 0.8111044284816183 0.758469633478465 0.4610728089698471 0.6897687340200769 0.7633026615967531 0.6765716555196384 0.6607209306228345 1.0 15.428297669166819 -14.522878705037758 0.2737499968988037 3.354552786640528 0.6425200236000786 0.5095761066486253 0.09971358180788635 189.65419550432324 1.8307509276504366 252.8540639797914 0.12457627017813801 3.000000277985902e-15 14.522878705037758 -2.7120327630404493 S(ph)YDSSMESR ddPTM_PC-9_Lapatinib_30min_R1 2 SYDSSMESR 9 0 Q9HCG8;B7WP74 Q9HCG8 CWC22 Pre-mRNA-splicing factor CWC22 homolog 1 S(1)YDSSMESR;S(0.994)Y(0.002)DS(0.002)S(0.002)MESR 87.568 0.010790000000000001 38432000.0 93207.0 78161.0 95104.0 78844.0 109526.0 95363.0 90447.0 92644.0 109683.0 94033.0 True False 91877.85108792938 77980.02300669762 87284.91623205628 84642.45077587372 103083.89601640093 91284.54679201056 95129.90309943007 96948.57845355003 97329.34552680592 110286.47875890353 0.8330835486078296 0.7070678462512996 0.7914380549121457 0.7674780419901697 0.9346920599555263 0.8277038837332639 0.8625708624480872 0.8790613277760786 0.882513855026389 1.0 16.75089640024173 -6.216680313168552 0.06436235077731196 1.290300681265496 0.3501530693581712 0.6246773379483781 0.04868972477804195 50.729519983791704 0.933791766091314 5.13154737398008 8.494721359053562 6.071831163425982e-07 6.216680313168552 -0.9401476119073249 S(ph)YDVPPPPMEPDHPFYSNISK ddPTM_PC-9_AZD4547_30min_R2 8 SYDVPPPPMEPDHPFYSNISK 21 0 P18669;Q8N0Y7 P18669 PGAM1;PGAM4 Phosphoglycerate mutase 1;Probable phosphoglycerate mutase 4 1 S(0.999)Y(0.001)DVPPPPMEPDHPFYSNISK;S(1)YDVPPPPMEPDHPFYSNISK;S(0.753)Y(0.247)DVPPPPMEPDHPFYSNISK;S(0.989)Y(0.011)DVPPPPMEPDHPFYSNISK;S(1)YDVPPPPMEPDHPFYSNISK;S(0.889)Y(0.111)DVPPPPMEPDHPFYSNISK;S(0.996)Y(0.004)DVPPPPMEPDHPFYSNISK;S(0.991)Y(0.009)DVPPPPMEPDHPFYSNISK 133.76 1.8438e-06 374660900.0 931501.7 938957.7000000001 1511384.2 2192477.6 1782727.1 1615609.0999999999 1374505.3 1715267.0 1305590.5 1600405.9 True False 1227699.8641610018 1242457.4142064108 1491342.2579871062 1687035.762761251 1535226.2142746865 1514584.8075767066 1496833.6089304115 1450211.8980644806 1374601.3484141664 1544376.176566644 0.7949487196120466 0.8045043902247706 0.9656599736617024 1.092373599359554 0.9940753020988066 0.9807097717240318 0.9692156818023921 0.9390276281576012 0.8900689930804877 1.0 20.5585927739806 -5.2706580059786505 5.121911710614843 0.9817460987998039 0.7971867639043387 0.6898079878417469 0.048140028455088975 0.09757275607343235 8.374039746888053 0.013784765131853359 0.03304677876566332 5.362187476568895e-06 5.2706580059786505 -0.18455933489546517 S(ph)YDVPPPPMEPDHPFYSNISK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SYDVPPPPMEPDHPFYSNISK 21 0 P18669;Q8N0Y7 P18669 PGAM1;PGAM4 Phosphoglycerate mutase 1;Probable phosphoglycerate mutase 4 1 S(0.735)Y(0.265)DVPPPPMEPDHPFYSNISK;S(0.995)Y(0.005)DVPPPPMEPDHPFYSNISK;S(0.957)Y(0.043)DVPPPPMEPDHPFYSNISK;S(0.953)Y(0.047)DVPPPPMEPDHPFYSNISK;S(0.999)Y(0.001)DVPPPPMEPDHPFYSNISK 126.3 7.2654e-06 305961000.0 840250.0 836649.0 1045917.0 1168216.0 1352098.0 1235538.0 1283615.0 1155928.0 1109739.0 856344.0 True False 982487.7293060276 919705.9834993866 1070855.6279423104 1102764.644927375 1087164.1030167069 1170744.2122396587 1162021.694632177 1125586.1148069531 1125966.8334550757 1011592.3883846279 0.9712288670686062 0.9091665714962811 1.0585841098036708 1.0901274639762133 1.074705697175872 1.1573280163853092 1.1487054548599005 1.1126874101972608 1.113063765982945 1.0 19.948196656079062 -5.435656900181316 3.043049691194387 1.1071978692597808 0.9397494120519456 0.6635325034003245 0.044238088283116775 0.13879797646229586 2.4532126887307193 0.011942597488803396 0.028009861403611988 3.667271807700016e-06 5.435656900181316 -0.1674484572078352 S(ph)YDVPPPPMEPDHPFYSNISK ddPTM_PC-9_Lapatinib_30min_R1 8 SYDVPPPPMEPDHPFYSNISK 21 0 P18669;Q8N0Y7 P18669 PGAM1;PGAM4 Phosphoglycerate mutase 1;Probable phosphoglycerate mutase 4 1 S(0.879)Y(0.12)DVPPPPMEPDHPFYSNISK;S(0.997)Y(0.003)DVPPPPMEPDHPFYSNISK;S(0.959)Y(0.041)DVPPPPMEPDHPFYSNISK;S(0.987)Y(0.013)DVPPPPMEPDHPFYSNISK;S(0.572)Y(0.428)DVPPPPMEPDHPFYSNISK;S(0.997)Y(0.003)DVPPPPMEPDHPFYSNISK;S(0.997)Y(0.003)DVPPPPMEPDHPFYSNISK;S(0.999)Y(0.001)DVPPPPMEPDHPFYSNISK 121.5 9.4705e-07 278189400.0 688295.2 560501.8 771124.0 525074.3 702255.3 675322.1 538692.4 617030.9 733868.7 563001.7 True False 678479.9842301181 559203.9925192266 707725.1613447213 563690.015618518 660950.0239410416 646440.1480357038 566583.2566298441 645700.4081960464 651212.6790259919 660315.7936923906 1.0275083387543344 0.8468735684667463 1.0717980216514653 0.8536673225191916 1.0009604953489064 0.9789863489723665 0.8580489245329002 0.9778660670607058 0.9862139982817989 1.0 19.332796627746504 -7.982588717848909 24.920971468409753 0.9894180968963779 0.946490356552197 0.06096242557181508 0.0726447932417692 638.2491787850684 913532.5106214029 0.036913021675894636 0.017727045393865853 1.0409054493253356e-08 7.982588717848909 -0.0429277403441809 S(ph)YEDLTESEDGAASGDSHK ddPTM_PC-9_AZD4547_30min_R2 2 SYEDLTESEDGAASGDSHK 19 0 A0A0A0MSQ9;Q86VX9-5;Q86VX9 A0A0A0MSQ9 MON1A Vacuolar fusion protein MON1 homolog A 1 S(0.999)YEDLT(0.001)ESEDGAASGDSHK;S(1)YEDLTESEDGAASGDSHK 233.34 1.1147e-43 18108300.0 47753.0 56114.0 107152.0 113719.0 99871.0 103600.0 94772.0 110484.0 103798.0 109539.0 True False 62937.460675896175 74251.75313092217 105731.09446812706 87502.84149103584 86005.63554894483 97121.87562260339 103206.52440230851 93411.2364697484 109284.5503721832 105704.0729510765 0.5954118788310627 0.7024493102104822 1.0002556336411283 0.8278095540512918 0.8136454267826673 0.9188092086816253 0.9763722581444526 0.8837051767435902 1.033872653353328 1.0 16.689671441631504 -4.259701210129125 0.8328420353448238 0.9339320754122511 6.637266922786488e-24 0.6769208638010682 0.0768413351734992 3.137066493841409 0.91549581429417 0.02799733380139247 3.3078618456626865 5.499190820769279e-05 4.259701210129125 -0.9339320754122511 S(ph)YEDLTESEDGAASGDSHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SYEDLTESEDGAASGDSHK 19 0 A0A0A0MSQ9;Q86VX9-5;Q86VX9 A0A0A0MSQ9 MON1A Vacuolar fusion protein MON1 homolog A 1 S(0.994)Y(0.002)EDLT(0.003)ESEDGAASGDSHK;S(0.941)Y(0.057)EDLT(0.002)ESEDGAASGDSHK 158.99 5.6323e-06 13797400.0 38304.0 60067.0 84324.0 74578.0 94306.0 77896.0 89651.0 91537.0 72365.0 68519.0 True False 44788.110661515144 66030.05479102649 86334.6039605508 70399.63644513823 75827.41628128542 73810.99663192914 81158.60826296764 89134.25074146854 73423.20122387024 80940.95230389437 0.5533430159476913 0.8157805525083937 1.0666368692624946 0.8697653590832664 0.9368238712659311 0.9119116409058832 1.0026890708952383 1.1012256244133658 0.9071205506478527 1.0 16.304582202562514 -4.870254940742692 2.88230304904245 0.971599755155447 0.5195294096432916 0.775161180378552 0.06965630143642818 0.1538560341164785 2.0510522443124346 0.018251249024888075 0.1491453174620061 1.3481712430635907e-05 4.870254940742692 -0.4520703455121554 S(ph)YEDLTESEDGAASGDSHK ddPTM_PC-9_Lapatinib_30min_R1 2 SYEDLTESEDGAASGDSHK 19 0 A0A0A0MSQ9;Q86VX9-5;Q86VX9 A0A0A0MSQ9 MON1A Vacuolar fusion protein MON1 homolog A 1 S(0.998)YEDLT(0.002)ESEDGAASGDSHK;S(1)YEDLTESEDGAASGDSHK 222.62 1.6536999999999998e-29 20636500.0 59182.0 84368.0 104964.0 84158.0 107063.0 93665.0 86750.0 93276.0 111851.0 82086.0 True False 58338.05382735037 84172.65107955468 96334.26509275696 90347.26006285801 100765.76483395674 89659.16629377934 91241.49052899002 97609.94348077926 99253.16253675398 96274.45572728009 0.6059556856141213 0.87429890352217 1.0006212381573603 0.9384343892713115 1.0466510983910347 0.9312871791013797 0.94772273537908 1.0138716728483228 1.030939741876202 1.0 16.554865441541864 -4.743244855064594 2.088546739310724 0.9866380645364816 0.47364196598102687 0.9059575181686547 0.03735838929860742 0.21850483345158736 0.9860831852604084 0.010008352872428043 0.2223020965947391 1.806155529091636e-05 4.743244855064594 -0.5129960985554547 S(ph)YEDMIGEEVPSDQYYWAPLAQHER ddPTM_PC-9_AZD4547_30min_R2 2 SYEDMIGEEVPSDQYYWAPLAQHER 25 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 S(0.987)Y(0.013)EDMIGEEVPSDQYYWAPLAQHER;S(0.988)Y(0.012)EDMIGEEVPSDQYYWAPLAQHER 83.165 1.7639000000000002e-05 10734300.0 15508.3 10829.0 19812.7 25344.0 22386.0 19345.9 19508.8 22852.0 17358.1 22064.0 True False 20439.616807321006 14329.262477363165 19549.970652611784 19501.332360896722 19278.090310487325 18136.19781474253 21245.04540644664 19320.74848671923 18275.613728736516 21291.546075758935 0.9599874398314421 0.6730024407986727 0.9182034307442809 0.9159190361990468 0.9054340272844728 0.8518027648255725 0.997816003161685 0.9074375537583191 0.8583507117664814 1.0 14.377993093775746 -1.5228788369606467 0.06499767800287011 1.1138926084575738 0.4115112366260425 0.1597698466616787 0.08168246150740797 486.87704947510593 2.3600076228821845 4.8031766777441955 31.77409657464925 0.029999993666949273 1.5228788369606467 -0.7023813718315313 S(ph)YEDMIGEEVPSDQYYWAPLAQHER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SYEDMIGEEVPSDQYYWAPLAQHER 25 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 S(0.966)Y(0.034)EDMIGEEVPSDQYYWAPLAQHER;S(0.761)Y(0.239)EDMIGEEVPSDQYYWAPLAQHER;S(0.989)Y(0.011)EDMIGEEVPSDQYYWAPLAQHER 89.381 4.9943e-05 8644200.0 7950.18 12052.800000000001 9377.6 11389.179999999998 16426.3 18167.3 25766.6 19548.0 20033.0 12741.3 True False 9295.988450787498 13249.32232981978 9601.19754874604 10751.081168819748 13207.684432181195 17214.574806296165 23325.80111397062 19034.88571281805 20325.94472628746 15051.196829924704 0.6176245354990818 0.8802836398682631 0.6379025971979181 0.7143007489905726 0.8775172221468629 1.143734614650062 1.5497638744311946 1.2646758877654831 1.3504537184628091 1.0 13.877590590251748 -6.755833779593066 2.498042449958852 1.316516815725061 0.7246938612002467 0.7683480584242848 0.14470507185864181 0.12343695638889432 1.5795285699042159 0.05224511694210819 0.048519754738075904 1.754551904633516e-07 6.755833779593066 -0.5918229545248144 S(ph)YELPDGQVITIGNER ddPTM_PC-9_AZD4547_30min_R2 2 SYELPDGQVITIGNER 16 0 P60709;A0A2R8Y793;Q6S8J3;A5A3E0;P63267-2;A0A2R8YEA7;Q9BYX7;Q562R1;P63261;P68133;P68032;P63267;P62736 P60709;P63261;P68133 ACTB;POTEE;POTEF;ACTG2;POTEKP;ACTBL2;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Actin, gamma-enteric smooth muscle;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 1 S(1)YELPDGQVITIGNER;S(1)YELPDGQVITIGNER 184.21 7.7178e-08 17539500.0 15973.4 16649.4 19036.2 13064.0 15581.5 15563.5 17095.0 19985.5 18675.1 17191.2 True False 21052.60893264003 22030.992953237645 18783.767549967888 10052.296636787987 13418.277681267682 14590.311884675575 18616.421882596835 16897.200196102192 19662.227660027715 16589.34132059403 1.2690442933080948 1.328020958004423 1.1322792862577187 0.6059491116931238 0.8088493341571201 0.8794991677314603 1.1221917448576686 1.0185576310450606 1.1852325707241311 1.0 14.017968984807808 -5.5273317106617315 24.99709849368546 0.9395447909987745 1.281437060884555 0.4607240588800804 0.15424550326395672 110.64821667604542 621131.213397968 0.04599112212410752 0.08005734110285603 2.96939716350438e-06 5.5273317106617315 0.34189226988578036 S(ph)YELPDGQVITIGNER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SYELPDGQVITIGNER 16 0 P60709;A0A2R8Y793;Q6S8J3;A5A3E0;P63267-2;A0A2R8YEA7;Q9BYX7;Q562R1;P63261;P68133;P68032;P63267;P62736 P60709;P63261;P68133 ACTB;POTEE;POTEF;ACTG2;POTEKP;ACTBL2;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Actin, gamma-enteric smooth muscle;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 1 S(0.997)YELPDGQVIT(0.002)IGNER;S(0.996)YELPDGQVIT(0.004)IGNER;S(0.999)Y(0.001)ELPDGQVITIGNER 206.62 5.1946000000000004e-17 15973300.0 22127.2 32146.5 30690.1 23771.2 31186.0 17758.0 29616.4 14890.7 19240.1 21531.1 True False 25872.897927879 35337.792071182776 31421.868376852388 22439.37673127021 25075.327170574157 16826.73921882764 26810.92018783232 14499.83490300081 19521.450063806882 25434.517989906184 1.0172356298690932 1.3893635446603216 1.2354025497680874 0.8822410843474757 0.9858778208623976 0.6615709889019881 1.0541155212169684 0.5700849101506521 0.7675179876243012 1.0 14.634500133464512 -5.805032694121783 4.035729714664499 0.829186829487318 1.2356282187542313 0.5071120179000813 0.16593855691872783 0.15915839828296743 5.442289779458649 0.04629887891095567 0.0745040774463177 1.566633127964299e-06 5.805032694121783 0.4064413892669133 S(ph)YELPDGQVITIGNER ddPTM_PC-9_Lapatinib_30min_R1 1 SYELPDGQVITIGNER 16 0 P60709;A0A2R8Y793;Q6S8J3;A5A3E0;P63267-2;A0A2R8YEA7;Q9BYX7;Q562R1;P63261;P68133;P68032;P63267;P62736 P60709;P63261;P68133 ACTB;POTEE;POTEF;ACTG2;POTEKP;ACTBL2;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Actin, gamma-enteric smooth muscle;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 1 S(0.995)YELPDGQVIT(0.005)IGNER 169.67 3.2814e-05 8368300.0 18171.0 20921.0 20450.0 20015.0 20414.0 16810.0 18222.0 22659.0 22032.0 18294.0 True False 17911.878207846705 20872.558709882418 18768.679939282818 21486.96986808271 19213.2886554682 16091.07548602391 19165.445999069234 23711.819860746382 19550.52415275465 21456.093524777247 0.8348154423899335 0.9728033057732075 0.8747482349295768 1.0014390477590809 0.8954700273505481 0.7499536421875737 0.8932402339194319 1.1051322009462836 0.9111874969307872 1.0 14.389099810468897 -7.663030028053743 12.36245545332032 1.006059218914236 0.8906767489589488 0.31813002537865653 0.07814590320449674 0.6099128640117878 72.25800842734891 0.03717983004036209 0.021455160892930862 2.1725509588286025e-08 7.663030028053743 -0.11538246995528734 S(ph)YESANGR ddPTM_PC-9_AZD4547_30min_R2 1 SYESANGR 8 0 Q96HJ9-2;A0A0A6YYJ8;Q9Y383-3;Q9Y383-2;Q9Y383 Q96HJ9-2 LUC7L2 Putative RNA-binding protein Luc7-like 2 1 S(0.999)YES(0.001)ANGR 80.24 0.019579 19956000.0 3215.3 2221.8 4940.0 9594.8 9568.5 12304.0 3087.7 11757.0 10082.0 8316.2 True False 4237.698517605363 2939.953400332949 4874.4923722613385 7382.867098182287 8240.078939332527 11534.628934947046 3362.499318332512 9940.225798982929 10614.913937189065 8025.052369254281 0.5280586745877082 0.3663469426812153 0.6074094159106771 0.9199774354704094 1.0267944133177322 1.4373275592740946 0.4190002960248555 1.2386493373010365 1.322722076912184 1.0 12.970295091553343 -5.762442111784287 2.1861183088135507 1.0689814381989615 0.4450718503150015 0.5001764132916229 0.2594616445747592 0.2589762631413636 2.5252035640516666 0.07879051967534194 0.15020358072341491 1.728056302175648e-06 5.762442111784287 -0.62390958788396 S(ph)YESSEDCSEAAGSPAR ddPTM_PC-9_AZD4547_30min_R2 1 SYESSEDCSEAAGSPAR 17 0 Q6P6C2-3;Q6P6C2;K7ER58 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 S(0.618)YES(0.374)S(0.007)EDCSEAAGSPAR 193.54 9.447200000000002e-43 0.0 11849.0 13203.0 16686.0 17513.0 14173.0 15402.0 13558.0 19420.0 17454.0 17033.0 True False 15616.735525489355 17470.611551262893 16464.732737561277 13475.648423152777 12205.32359378794 14438.910505205973 14764.635734673755 16419.085227204952 18376.582806952785 16436.679854441703 0.9501149662697377 1.0629039262173006 1.0017067244338882 0.8198522172658389 0.7425662422018691 0.8784566368069844 0.8982736091123592 0.9989295510168378 1.1180227983808335 1.0 14.004631289197036 -7.923592124172406 3.8159290690798873 1.0600082322842583 0.9066463392442667 0.3297159430658929 0.08826228528752708 0.295357162647116 8.326535999648309 0.06357320959269241 0.027308151583380697 1.1923613108799392e-08 7.923592124172406 -0.1533618930399916 S(ph)YESSEDCSEAAGSPAR ddPTM_PC-9_Lapatinib_30min_R1 1 SYESSEDCSEAAGSPAR 17 0 Q6P6C2-3;Q6P6C2;K7ER58 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 S(0.483)YES(0.434)S(0.083)EDCSEAAGSPAR 169.15 3.2198000000000003e-24 0.0 5644.8 10772.0 10804.0 7137.2 10183.0 9708.5 10501.0 10681.0 10551.0 7663.6 True False 5564.3041168704585 10747.058095829712 9915.736824646046 7662.093497001242 9584.055960548281 9293.290086618865 11044.690398212391 11177.278252907543 9362.635273044403 8988.243048894885 0.6190647144944079 1.1956795157148177 1.1031896635088432 0.8524573106579829 1.0662880285292966 1.0339384500468627 1.2287930286409365 1.2435442824703993 1.041653549210104 1.0 13.133823421273192 -6.848494399151432 2.19935403483733 1.1454021407723565 0.9750412095269188 0.17416570286078514 0.1625547113903139 0.5468700618410433 5.414972154887504 0.06483799905584162 0.05644097702972135 1.4174429912798467e-07 6.848494399151432 -0.17036093124543772 S(ph)YGNSSDSR ddPTM_PC-9_Lapatinib_30min_R1 2 SYGNSSDSR 9 0 F8WAX7;F6XHT0;Q9Y6D0 F8WAX7 SELK Selenoprotein K 1 S(1)YGNSSDSR;S(0.999)YGNSSDSR 99.73200000000001 0.004046500000000001 14296900.0 52081.0 98402.0 53761.0 39347.0 56053.0 45488.0 44494.0 44738.0 87156.0 32250.0 True False 51338.31538951431 98174.15621480078 49340.97810346131 42240.70963774422 52756.072744438105 43542.584277707065 46797.68160918597 46816.69080409864 77339.57348663233 37824.369529576164 1.3572814571138094 2.5955265728364636 1.304475889938626 1.116759120194053 1.3947641005142553 1.151178058464653 1.2372362630550462 1.2377388278075876 2.0447022501236374 1.0 15.207028414823334 -5.319856282861783 23.73384343781724 1.3070792783548304 1.9764042154223647 0.32334061763253075 0.385086924310609 142.21521033585339 57779.31903084184 0.09449851476617832 0.19671454305888902 4.7878850725269735e-06 5.319856282861783 0.6693249370675343 S(ph)YNTPLLNPVQEHEAEGAAAGGTSIR ddPTM_PC-9_AZD4547_30min_R2 2 SYNTPLLNPVQEHEAEGAAAGGTSIR 26 0 P85299;P85299-5;P85299-2;P85299-4;P85299-3 P85299 PRR5 Proline-rich protein 5 1 S(0.959)Y(0.013)NT(0.028)PLLNPVQEHEAEGAAAGGTSIR;S(0.98)Y(0.006)NT(0.014)PLLNPVQEHEAEGAAAGGTSIR 152.01 3.9142999999999996e-10 16894600.0 14390.3 18397.3 28165.0 38011.8 28798.5 25433.0 25171.6 32450.5 24883.1 26739.2 True False 18966.116063165624 24343.86744619019 27791.513697315906 29248.766786455715 24800.325373294432 23842.67048947563 27411.823636149446 27436.02086330658 26198.369866144516 25803.068746779056 0.735033350075197 0.9434485364935125 1.0770623436324822 1.133538304047916 0.9611386000895806 0.9240246082145505 1.0623474248415203 1.0632851903218437 1.015319926604265 1.0 14.655255034441511 -4.821037783075151 2.951926197331838 1.0300402116839371 0.6992919275548924 0.7086026338358213 0.057094369448126174 0.20430568569435842 2.7077691438555367 0.0159062047493506 0.1554959469933894 1.5099487847995332e-05 4.821037783075151 -0.33074828412904467 S(ph)YNTPLLNPVQEHEAEGAAAGGTSIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SYNTPLLNPVQEHEAEGAAAGGTSIR 26 0 P85299;P85299-5;P85299-2;P85299-4;P85299-3 P85299 PRR5 Proline-rich protein 5 1 S(0.998)Y(0.001)NT(0.001)PLLNPVQEHEAEGAAAGGTSIR;S(0.66)Y(0.112)NT(0.228)PLLNPVQEHEAEGAAAGGTSIR 112.75 6.8039e-11 9381500.0 9685.7 11481.0 13463.6 13173.8 14737.1 14448.800000000001 12747.2 11527.8 9726.1 12213.5 True False 11325.297708705019 12620.75780471434 13784.623284987332 12435.714696035855 11849.471046157523 13691.079492341301 11539.692934263983 11225.20746471372 9868.325812526564 14427.710867987194 0.7849684411013573 0.8747581595024754 0.9554269149912914 0.8619326246430913 0.8212994531550825 0.9489432951362811 0.7998284024299886 0.7780310797342548 0.6839841678850673 1.0 13.816554796399945 -7.418202104614785 12.842906670477493 0.7963938816395081 0.8752372192747261 0.08211658488696993 0.0880491835684519 1.587704062130429 188.10026712421998 0.0354385953324543 0.023886299092214985 3.817665694314097e-08 7.418202104614785 0.078843337635218 S(ph)YNTPLLNPVQEHEAEGAAAGGTSIR ddPTM_PC-9_Lapatinib_30min_R1 2 SYNTPLLNPVQEHEAEGAAAGGTSIR 26 0 P85299;P85299-5;P85299-2;P85299-4;P85299-3 P85299 PRR5 Proline-rich protein 5 1 S(0.968)Y(0.022)NT(0.01)PLLNPVQEHEAEGAAAGGTSIR;S(0.886)Y(0.08)NT(0.034)PLLNPVQEHEAEGAAAGGTSIR 148.56 1.6425999999999998e-10 14978200.0 15396.9 28975.0 33324.0 30839.0 32239.0 27954.0 25057.0 21054.0 28756.0 26185.0 True False 15177.337382554351 28907.910167718706 30584.22935435995 33107.00293588823 30342.765404312686 26758.472583956725 26354.328855157397 22032.245701405813 25517.196465895642 30711.04236068067 0.4941980543775319 0.9412871705302158 0.9958707684085945 1.0780162570540135 0.9880083211750739 0.871298091080607 0.8581385335490543 0.7174046859970369 0.8308801819949067 1.0 14.906469859074706 -7.158984412890104 3.1738954079280877 0.8270141727787957 0.9172334574476294 0.002704336481644032 0.16122602488590318 0.8876425813630766 17.04478489796382 0.06957641892751916 0.05149093346173687 6.93450693963937e-08 7.158984412890104 0.09021928466883367 S(ph)YS(ph)TSLKS(ph)RLT(ph)ISK ddPTM_PC-9_AZD4547_30min_R2 1 SYSTSLKSRLTISK 14 2 A0A0B4J1V2 A0A0B4J1V2 IGHV2-26 4 S(0.552)Y(0.452)S(0.695)T(0.284)S(0.284)LKS(0.736)RLT(0.927)IS(0.07)K 68.847 0.019195 3495700.0 14232.0 19676.0 18023.0 16872.0 20198.0 23013.0 22209.0 24713.0 26759.0 23070.0 True False 18757.479956010175 26035.882214848814 17784.003243981006 12982.421069801512 17393.856342858177 21573.993472036444 24185.557975466123 20894.1736982449 28173.42611041879 22262.326321961486 0.8425660321718568 1.1695041137351745 0.7988384945394196 0.5831565345888641 0.7813135110547441 0.9690808211158952 1.0863895185835721 0.9385440405494856 1.2655203100956294 1.0 14.44231673583211 -6.97659170310114 4.074052438532935 1.0647320732561545 0.83848020484506 0.34215735084234755 0.1552377266390575 0.28853313941888575 10.87655758270118 0.06315791749235211 0.053035996688900876 1.0553786320626025e-07 6.97659170310114 -0.22625186841109446 S(ph)YSAGNASQLEQLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SYSAGNASQLEQLSR 15 0 Q14678-2;Q14678 Q14678-2 KANK1 KN motif and ankyrin repeat domain-containing protein 1 1 S(0.569)YS(0.431)AGNASQLEQLSR;S(0.868)YS(0.132)AGNASQLEQLSR 135.69 2.4551e-05 29655000.0 51824.0 56257.0 70770.0 79940.0 104846.0 90669.0 92820.0 106967.0 76637.0 56830.0 True False 60596.7796293431 61841.82317043939 72457.42519671972 75461.2209689769 84302.17894330862 85914.15802634766 84027.4176413946 104159.22959090499 77757.67114204032 67132.82913396755 0.9026400408125007 0.9211860123909028 1.0793143404120005 1.1240584069291872 1.255751917963693 1.2797637033127394 1.251659117087303 1.551539402325039 1.1582659653277871 1.0 16.03473082177749 -5.667252979393283 1.066835871280496 1.2858802868880796 0.8758131128364486 0.49210097627791993 0.1316633417076122 0.4722248100889811 0.9863951582445156 0.04704377370688638 0.15737653379640076 2.1515280903624968e-06 5.667252979393283 -0.41006717405163107 S(ph)YSCSSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SYSCSSPK 8 0 Q8N1W1-5;Q8N1W1-4;Q8N1W1-3;Q8N1W1;Q8N1W1-6;Q8N1W1-2 Q8N1W1-5 ARHGEF28 Rho guanine nucleotide exchange factor 28 1 S(0.405)YS(0.405)CS(0.189)S(0.001)PK 99.973 0.0050353 14229000.0 18945.0 15435.0 16796.0 15931.0 24133.0 21965.0 25738.0 29034.0 23620.0 19896.0 True False 22152.01431919392 16967.284793638682 17196.480339184713 15038.437718998875 19404.31189019003 20813.116732827402 23299.91031301671 28271.88826406585 23965.39781535016 23502.987303350656 0.9425190948401637 0.7219203488749609 0.7316721111759751 0.6398521824012964 0.8256104485672634 0.8855519710832769 0.9913595243143839 1.2029061624874946 1.0196745420499624 1.0 14.520556519055704 -7.112237993549135 1.775220588162814 1.0828606418536533 0.7572558652218713 0.6862411179019843 0.09024075782870782 0.1960789399682972 1.2228921343717405 0.044791342512632976 0.03128147445393316 7.722572718256962e-08 7.112237993549135 -0.325604776631782 S(ph)YSCSSPK ddPTM_PC-9_Lapatinib_30min_R1 1 SYSCSSPK 8 0 Q8N1W1-5;Q8N1W1-4;Q8N1W1-3;Q8N1W1;Q8N1W1-6;Q8N1W1-2 Q8N1W1-5 ARHGEF28 Rho guanine nucleotide exchange factor 28 1 S(0.927)YS(0.073)CSSPK 139.38 0.0027427 13767000.0 12642.0 15531.0 16373.0 18816.0 20987.0 24240.0 29150.0 21333.0 25537.0 20281.0 True False 12461.722761741126 15495.038923721788 15026.875141607714 20199.791408335946 19752.585922029535 23203.311706199864 30659.244367954565 22324.20905994537 22660.7541434684 23786.543827266167 0.5238980009973722 0.651420359184761 0.6317384841921686 0.8492108628737068 0.8304100867057213 0.9754805857756539 1.2889322883810603 0.9385226042950996 0.9526711534061837 1.0 14.53785804368356 -6.064695655014923 1.0094182097636697 1.043582212947764 0.5633311277388785 0.7568114673678782 0.10356663224589048 0.28571622901781124 0.598146665885617 0.04656162275046692 0.09138660674013523 8.615973310440037e-07 6.064695655014923 -0.4802510852088856 S(ph)YSLSELSVLQAK ddPTM_PC-9_AZD4547_30min_R2 1 SYSLSELSVLQAK 13 0 Q9P0V3;Q9P0V3-2 Q9P0V3 SH3BP4 SH3 domain-binding protein 4 1 S(0.986)YS(0.013)LS(0.001)ELSVLQAK 195.87 1.0736e-06 229970000.0 21450.0 21257.0 26353.0 31072.0 30524.0 27741.0 22941.0 27546.0 29039.0 26757.0 True False 28270.653812283468 28127.909546708735 26003.542001255682 23908.83045761452 26286.269482592477 26006.350884620126 24982.7045573942 23289.398644108525 30573.94225570652 25820.24557419694 1.0949025922718298 1.0893742069911962 1.0070989420504164 0.9259722332582088 1.018048779089121 1.0072077281328868 0.9675626238954241 0.9019820736090296 1.1841073380905451 1.0 14.656215101611721 -5.28029430837805 4.692802455839015 0.9943170808153146 1.0937186862548103 0.20230307021647898 0.07123083692626397 0.25720508027855815 15.599903144431504 0.018002906348973724 0.043084573697086834 5.244519344122979e-06 5.28029430837805 0.09940160543949572 S(ph)YSLSELSVLQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SYSLSELSVLQAK 13 0 Q9P0V3;Q9P0V3-2 Q9P0V3 SH3BP4 SH3 domain-binding protein 4 1 S(0.812)YS(0.049)LS(0.139)ELSVLQAK;S(0.895)YS(0.026)LS(0.08)ELSVLQAK 201.08 2.8905999999999997e-07 265920000.0 322800.0 298980.0 317590.0 319600.0 483230.0 380670.0 349910.0 437160.0 357500.0 306270.0 True False 377443.6644093843 328660.7585100154 325162.55006678257 301693.84815717995 388544.5503955801 360706.9950687647 316763.9916709794 425685.0132093071 362727.7611764467 361794.3265680135 1.0432547906149348 0.9084187738036036 0.8987497210121548 0.8338821977089922 1.0739376542504677 0.9969946142893857 0.875536094431904 1.1765939428828571 1.0025800144996406 1.0 18.46481025913348 -7.054036665426629 0.942734172849142 1.0443067615850992 0.931240364797431 0.13970104148428897 0.09118641416114572 1.0057066725154027 1.8282054417642983 0.06361291619564846 0.04380219046067595 8.830053493111864e-08 7.054036665426629 -0.11306639678766817 S(ph)YSPAHNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SYSPAHNR 8 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.957)YS(0.043)PAHNR;S(0.731)YS(0.269)PAHNR 89.029 0.010532 28128000.0 19028.0 21320.0 24894.0 24366.0 26902.0 21373.1 24083.2 25186.0 22720.0 17836.5 True False 22249.064579869206 23436.508701028622 25487.56737102074 23000.85201563783 21630.746217622847 20252.257010807814 21801.8649487312 24524.89418677284 23052.2370179829 21070.116256343692 1.0559535746828432 1.1123103648738752 1.2096548049822489 1.0916338446264073 1.0266078247722228 0.961183923449419 1.0347292195014441 1.1639657744835175 1.0940726067917372 1.0 14.362910653931902 -6.001524303463674 24.99758035267364 1.0508999329501867 1.1289462711096674 0.2496248415272092 0.06185279530008262 93.26542298013369 1529568.7160078639 0.01923910394356492 0.02808606032788762 9.96496313850313e-07 6.001524303463674 0.0780463381594807 S(ph)YSPDGK ddPTM_PC-9_AZD4547_30min_R2 2 SYSPDGK 7 0 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2 A0A0R4J2E8 MATR3 Matrin-3 1 S(0.969)YS(0.031)PDGK;S(0.984)YS(0.016)PDGK 104.01 0.010412000000000001 533360000.0 991760.0 1002210.0 1112070.0 1006030.0 1095620.0 1348920.0 1133870.0 1214110.0 1173380.0 1155890.0 True False 1307119.0501105033 1326154.7832152685 1097323.225186371 774105.3265085585 943512.0747778137 1264571.8191587075 1234782.233402753 1026497.1969722847 1235402.4712972525 1115422.6429255353 1.1718598850406925 1.1889258225357735 0.9837734890411646 0.694001804085877 0.8458785382939387 1.133715392258833 1.107008398327078 0.9202764561780666 1.1075644547227708 1.0 20.089159032222618 -5.277820158847847 6.846544521168806 0.9666872233054397 1.1810763395175647 0.2975824736455013 0.12649421247395853 0.19225829033583886 47.14646702647447 0.036461745266796186 0.08173398990290802 5.274482322848945e-06 5.277820158847847 0.21438911621212509 S(ph)YSPDGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SYSPDGK 7 0 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2 A0A0R4J2E8 MATR3 Matrin-3 1 S(0.5)YS(0.5)PDGK;S(0.722)YS(0.278)PDGK 117.81 0.007196800000000001 536620000.0 595700.0 898470.0 711850.0 732510.0 776410.0 607980.0 717830.0 555890.0 574830.0 504530.0 True False 696540.2443886949 987664.1638186317 728823.2037061598 691469.8395294609 624278.0340058182 576096.4585123793 649831.9457608499 541298.4765141398 583235.8012784824 595997.2951427163 1.1686969891732526 1.6571621580633644 1.2228632741221372 1.1601895598601382 1.047451119482564 0.9666091829736048 1.0903270049325349 0.9082230421608233 0.9785880003680587 1.0 19.184946257652697 -5.8338343421774725 1.646633339399105 0.9942751555064475 1.413547355766025 0.6266456076081652 0.12402952222703596 0.21895434191495686 1.2098493832135022 0.038128992181011845 0.07610481709450886 1.466106967961199e-06 5.8338343421774725 0.41927220025957745 S(ph)YSPDGK ddPTM_PC-9_Lapatinib_30min_R1 3 SYSPDGK 7 0 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2 A0A0R4J2E8 MATR3 Matrin-3 1 S(0.584)YS(0.416)PDGK;S(0.939)YS(0.061)PDGK;S(0.729)YS(0.271)PDGK 116.37 0.007822299999999999 1332990000.0 1945930.0 3335740.0 3053410.0 2808230.0 3475610.0 3243750.0 3292500.0 3575570.0 3184590.0 2877570.0 True False 1918180.6813601397 3328016.2989772605 2802370.41630345 3014756.6021806556 3271181.4531121724 3105022.374050569 3462969.5396737703 3741704.0354600255 2825907.938980621 3374954.140378997 0.5683575543769415 0.9860923024582297 0.830343257934981 0.8932733532912858 0.9692521193028207 0.9200191306012484 1.0260789911903483 1.1086681121657682 0.8373174334935644 1.0 21.686436467962515 -4.758333541838048 24.99928102891194 0.9518990487431861 0.5683570293511262 0.6670901986068352 0.08137646729665352 54.09155175130067 435315.1624330512 0.020811047117315042 0.1438055918527038 1.744481861473578e-05 4.758333541838048 -0.3835420193920599 S(ph)YSPDGKESPSDKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SYSPDGKESPSDKK 14 2 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2 A0A0R4J2E8 MATR3 Matrin-3 1 S(0.5)YS(0.5)PDGKESPSDKK 107.73 0.0021154 41117000.0 46412.0 20453.0 28139.0 64027.0 57928.0 63110.0 60127.0 74258.0 50905.0 44967.0 True False 54268.634921215526 22483.438670832016 28809.94047775175 60439.77476833474 46577.42423962743 59800.400501194505 54431.33527821727 72308.8061828548 51649.38932220156 53119.16114142385 1.02163953185803 0.423264189187257 0.5423643720774974 1.1378149328717857 0.8768478876317385 1.125778329631046 1.0247024634538167 1.3612565527972222 0.9723306658531525 1.0 15.696944743352818 -5.764356610246431 24.99995251317259 1.0785324406686796 0.6385068041550251 0.4998836966834258 0.18683243305541816 55.98047439260096 479745.6237053366 0.05107262869053697 0.07964577484465564 1.7204552852226506e-06 5.764356610246431 -0.44002563651365445 S(ph)YSPDHR ddPTM_PC-9_AZD4547_30min_R2 2 SYSPDHR 7 0 A0A024RAC6;Q14241 A0A024RAC6 TCEB3 Transcription elongation factor B polypeptide 3 1 S(0.728)YS(0.272)PDHR;S(0.986)YS(0.014)PDHR 84.743 0.01975 61535000.0 57240.0 57547.0 103543.0 154824.0 112567.0 94418.0 63948.0 82746.0 76624.0 87747.0 True False 75441.12933403757 76147.94235707998 102169.95216620555 119131.71880695524 96939.01509785691 88514.02753412133 69639.24811630906 69959.50701391876 80674.1882090036 84675.00423810811 0.8909492241877583 0.8992965874905677 1.2066128969878906 1.4069289972747332 1.1448362591782353 1.0453383301312604 0.8224298155389735 0.8262120284894344 0.9527509202378764 1.0 16.369648533477886 -7.081086159056302 4.337319390509757 0.8873129521214783 1.1184637505179973 0.3083736577833913 0.1472487998347485 0.2983262072083987 10.227101982511789 0.06505405997094392 0.05058323045477254 8.296861509463073e-08 7.081086159056302 0.23115079839651897 S(ph)YSPDHR ddPTM_PC-9_Lapatinib_30min_R1 1 SYSPDHR 7 0 A0A024RAC6;Q14241 A0A024RAC6 TCEB3 Transcription elongation factor B polypeptide 3 1 S(0.548)YS(0.452)PDHR 77.318 0.02997 34631000.0 37529.0 29888.0 41729.0 23512.0 25511.0 37443.0 32984.0 38592.0 43306.0 22217.0 True False 36993.8295780243 29818.796172313232 38298.202698598194 25241.150913732727 24010.493136555768 35841.650173896116 34691.75012804852 40385.12520702253 38428.42224760318 26057.178847708325 1.419717375938333 1.1443601145998863 1.4697754857666199 0.9686831817540614 0.9214540559776463 1.375500025669445 1.3313701506523448 1.5498656029900306 1.474772939626305 1.0 14.669393274555224 -6.936229140066874 24.999898004019066 1.3803483298900743 1.1825866271839887 0.11924282695631117 0.2094827995361766 114.41899832385216 44854.28352878111 0.07456755793256474 0.06576239813537553 1.1581661296773643e-07 6.936229140066874 -0.19776170270608562 S(ph)YSPSFQR ddPTM_PC-9_Lapatinib_30min_R1 2 SYSPSFQR 8 0 Q9P227;Q9P227-2 Q9P227 ARHGAP23 Rho GTPase-activating protein 23 1 S(0.617)YS(0.322)PS(0.061)FQR;S(0.531)YS(0.395)PS(0.074)FQR 122.28 0.0033354999999999995 30369000.0 132933.0 110277.0 145866.0 127375.0 114425.0 99254.0 106288.0 97931.0 117163.0 89013.0 True False 131037.35104307371 110021.66038189849 133873.46053904315 136742.58241054384 107694.74646820549 95009.13779237473 111791.07256882174 102481.23177469232 103966.869158914 104398.77844763314 1.2551617269047126 1.0538596525541322 1.282327844536942 1.3098101763626906 1.0315709443116292 0.9100598609018372 1.0708082434594444 0.9816324797909137 0.9958628894404565 1.0 16.67174530571384 -6.385160549325762 5.816289632648209 0.99323078129617 1.216184009234039 0.695410224623638 0.07378696568090393 0.14034442542284106 6.092379596177902 0.023608792155517245 0.026775867713163242 4.119452036667356e-07 6.385160549325762 0.22295322793786898 S(ph)YSSPDITQAIQEEEK ddPTM_PC-9_AZD4547_30min_R2 1 SYSSPDITQAIQEEEK 16 0 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 S(0.495)YS(0.495)S(0.01)PDITQAIQEEEK 147.53 3.0137e-05 19536000.0 32440.0 25292.0 31114.0 42784.0 36848.0 33663.0 28591.0 32549.0 33493.0 35049.0 True False 42755.24520608276 33467.14438798312 30701.40803047355 32920.80980621075 31732.291242778374 31558.04728845274 31135.543611893918 27519.299951611407 35263.37160268532 33821.94517808531 1.2641273286016004 0.9895097461652772 0.9077363193872808 0.9733564888970831 0.9382160332794545 0.933064231589511 0.9205722334405524 0.8136521955408508 1.0426180817516661 1.0 15.045672014403124 -4.762504049398553 3.2839380892824686 0.9347884470397656 1.3178272486494764 0.7366765604107803 0.057493170020394176 0.164742464517774 2.679011408979038 0.013887674935912513 0.16639894007860223 1.727809870187107e-05 4.762504049398553 0.3830388016097108 S(ph)YSSPDITQAIQEEEKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SYSSPDITQAIQEEEKR 17 1 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 S(0.803)Y(0.001)S(0.183)S(0.013)PDITQAIQEEEKR 122.16 2.8456e-05 140090000.0 69110.0 80006.0 88039.0 92707.0 101600.0 93225.0 97048.0 83417.0 67598.0 67614.0 True False 80808.95801528051 87948.46693876607 90138.18364976691 87512.92735014907 81692.20934170247 88336.1168867669 87854.91087332503 81227.39213761748 68586.4928671482 79871.88296787061 1.0117322268186273 1.1011192383450426 1.1285346019202533 1.095666260746002 1.0227905779379725 1.1059726352301114 1.0999479116908473 1.0169710431177907 0.8587063471977732 1.0 16.285400104957546 -8.017320040234464 4.840601327620292 0.9293273782892489 1.08184079638752 0.6215673953169096 0.04706745737546989 0.11447155660357212 7.213367536708791 0.03016481706339426 0.011973429459305863 9.609039082236491e-09 8.017320040234464 0.15251341809827113 S(ph)YTLVVAK ddPTM_PC-9_AZD4547_30min_R2 4 SYTLVVAK 8 0 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;E9PJP4;E9PQN0;E9PRG1;E9PIG0;E9PQD2;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 S(1)YTLVVAK;S(1)YTLVVAK;S(0.998)YT(0.002)LVVAK;S(0.998)YT(0.002)LVVAK 154.01 5.0338000000000005e-05 62215000.0 296163.0 306112.0 330063.0 405414.0 479990.0 418101.0 307783.0 460865.0 323614.0 388335.0 True False 390336.67342691484 405056.7176535776 325686.14896066725 311952.06588386104 413351.67373049306 391957.07837534935 335175.09074532386 389648.90387414116 340719.5753689251 374739.5098499756 1.0416213480750494 1.080902085333194 0.8691001092760502 0.8324504293896017 1.103037344250078 1.0459454316206656 0.8944215433262133 1.0397860210420151 0.9092171132564322 1.0 18.515528567555265 -9.135585397771722 0.0026517791471322885 8.087456288595812e-06 1.9479952789498394 0.003221525704345085 0.09140358247391867 503244.1434656774 516.1686797926004 190968.43155140654 188195.72369574278 7.318374037369876e-10 9.135585397771722 1.9479871914935507 S(ph)YTLVVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SYTLVVAK 8 0 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;E9PJP4;E9PQN0;E9PRG1;E9PIG0;E9PQD2;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 S(0.999)YTLVVAK;S(0.991)YT(0.009)LVVAK;S(0.989)YT(0.011)LVVAK;S(1)YTLVVAK 154.85 4.7565e-05 52160800.0 327179.0 363808.0 285758.0 276713.0 369865.0 283191.0 257609.0 343788.0 254167.0 211555.0 True False 382563.94262019265 399924.45391668886 292571.5544632501 261209.66772564987 297392.60834811785 268339.96543073654 233206.41059235047 334763.92927349557 257883.71153827678 249908.2468315418 1.5308175999412754 1.6002851405951002 1.1707158854204072 1.0452222807265985 1.190007181109891 1.0737539430286156 0.9331681268987906 1.3395473479478783 1.0319135715121521 1.0 17.931038984771625 -5.318662231903146 4.42417105489053 1.1002878667287392 1.5687495688765285 0.7526957176809294 0.10766573372617637 0.09205267357536027 3.7502297083045737 0.027665455803381853 0.06333756565504231 4.801067015537546e-06 5.318662231903146 0.46846170214778926 S(ph)YTLVVAK ddPTM_PC-9_Lapatinib_30min_R1 2 SYTLVVAK 8 0 E9PK52;E9PHY5;O43491-4;E9PII3;O43491-2;O43491-3;A0A2R8Y5B3;E9PJP4;E9PQN0;E9PRG1;E9PIG0;E9PQD2;O43491 E9PK52;O43491 EPB41L2 Band 4.1-like protein 2 1 S(0.97)YT(0.03)LVVAK;S(0.916)YT(0.084)LVVAK 135.43 0.0036791 22535000.0 166523.0 191539.0 161488.0 192602.0 161998.0 164370.0 136099.0 146090.0 164713.0 204309.0 True False 164148.35148342204 191095.50321362077 148211.08000170707 206766.59358143772 152469.59614032204 157340.27826518443 143145.54028247853 152877.87472776583 146161.28743521587 239623.53842537024 0.6850259893584927 0.7974821858877469 0.6185163651936757 0.8628809796406304 0.6362880589371152 0.6566144515647715 0.5973767903734575 0.6379918923339788 0.6099621447695849 1.0 17.87041010669372 -10.619553528826279 4.6856576695965355 1.0000170093122493 0.6798108028825469 0.5819725895957604 0.08185399987836303 1.6302750019478806e-05 3.1429090225383482e-06 0.08063870128967428 0.01955661420736272 2.4013002781538047e-11 10.619553528826279 -0.32020620642970243 SAAAT(ph)SPAPHLVAGPLLGTVGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAAATSPAPHLVAGPLLGTVGK 22 0 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 S(0.121)AAAT(0.759)S(0.121)PAPHLVAGPLLGTVGK 99.711 0.00021857 5981200.0 31763.0 22519.0 28945.0 34819.0 46771.0 35443.0 44977.0 41571.0 38635.0 36335.0 True False 37139.84855215395 24754.53749711368 29635.158574523783 32868.20431472109 37606.55829843278 33584.30668616444 40716.45295471881 40479.80529811537 39199.96378476095 42922.24787229827 0.8652820016009403 0.576729754945805 0.6904381770193847 0.7657614860365691 0.8761553777500035 0.782445196861172 0.9486095200758796 0.9430961169263635 0.9132784448146375 1.0 15.389438012710443 -6.725835410035293 0.7692062321374056 0.9633990611628209 0.6943627444063655 0.6078082955543425 0.07814333508877232 0.4355072594072236 0.5673300623682906 0.0528249373029673 0.053481777862414676 1.880029179777329e-07 6.725835410035293 -0.26903631675645545 SAAATWS(ph)WTR ddPTM_PC-9_AZD4547_30min_R2 2 SAAATWSWTR 10 0 Q96NG3-2 Q96NG3-2 1 SAAAT(0.001)WS(0.996)WT(0.003)R;SAAAT(0.001)WS(0.975)WT(0.024)R 80.24 0.017927000000000002 4125200.0 5699.5 3411.3 32888.0 54103.0 32011.0 20921.8 10139.0 38856.0 12845.7 17891.3 True False 7511.822443035415 4513.936013392648 32451.883631362558 41630.38923301749 27566.825200080846 19613.55653861956 11041.351358154388 32851.69802205333 13524.697476983685 17264.93103268788 0.4350913669341164 0.26145114653782076 1.8796416603067256 2.4112687826089907 1.5966947767059294 1.1360344562909055 0.6395247879791515 1.9027992616857174 0.7833623807345207 1.0 14.075556950694244 -5.250358216600687 24.733954931885684 1.4547964415426446 0.3482710563479811 0.3981590150758818 0.5248991135877307 642.69578657349 1434535.347408067 0.14177549276252868 0.3673234912035904 5.618776836916212e-06 5.250358216600687 -1.1065253851946635 SAADS(ph)ISESVPVGPK ddPTM_PC-9_AZD4547_30min_R2 2 SAADSISESVPVGPK 15 0 P45974-2;P45974 P45974-2 USP5 Ubiquitin carboxyl-terminal hydrolase 5 1 SAADS(1)ISESVPVGPK;SAADS(0.955)IS(0.005)ES(0.04)VPVGPK 220.6 3.2337999999999997e-18 23284000.0 108906.0 113937.0 137344.0 200085.0 182268.0 168351.0 163851.0 201851.0 151347.0 195450.0 True False 143535.8426144776 150764.9070905279 135522.7288210246 153958.49453243453 156963.23437469444 157823.9853565726 178433.42157855374 170659.56602453865 159346.89343897568 188607.35499035026 0.7610299323789432 0.799358578027042 0.7185442414372354 0.8162910430524384 0.8322222342958214 0.8367859533614019 0.9460575998623327 0.9048404609314952 0.844860442728378 1.0 17.525026411325783 -6.719316499863693 0.8760273302406802 0.9242625861106724 0.7610016099948558 0.695225047501659 0.044161233129221246 0.3471396696984807 0.581509389013412 0.027044916289607014 0.026390094078598044 1.9084619259195014e-07 6.719316499863693 -0.16326097611581658 SAADS(ph)ISESVPVGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAADSISESVPVGPK 15 0 P45974-2;P45974 P45974-2 USP5 Ubiquitin carboxyl-terminal hydrolase 5 1 S(0.001)AADS(0.923)IS(0.067)ES(0.01)VPVGPK 96.70700000000001 0.0025922 6432200.0 41666.0 38306.0 36468.0 40542.0 44275.0 43388.0 41384.0 41193.0 36152.0 35813.0 True False 48719.23085898835 42108.76652446539 37337.535425660186 38270.563178937424 35599.63158074687 41112.656899791305 37463.80792578611 40111.727397591254 36680.65460713547 42305.613404448006 1.1516020437577679 0.9953470269275916 0.8825669319271594 0.9046213988925087 0.8414871861189922 0.9718014606418336 0.8855517013221506 0.9481419643799306 0.8670398950716756 1.0 15.368561482456322 -4.844396126672303 2.5461808682898583 0.9093719739920789 1.185327449463225 0.7102633909190489 0.04656197283734391 0.21084467491029768 1.9709658324157762 0.011329432342899971 0.12039428526508163 1.4308821742535111e-05 4.844396126672303 0.2759554754711462 SAADS(ph)ISESVPVGPK ddPTM_PC-9_Lapatinib_30min_R1 3 SAADSISESVPVGPK 15 0 P45974-2;P45974 P45974-2 USP5 Ubiquitin carboxyl-terminal hydrolase 5 1 SAADS(0.993)IS(0.003)ES(0.004)VPVGPK;S(0.258)AADS(0.633)IS(0.018)ES(0.091)VPVGPK;S(0.002)AADS(0.934)IS(0.06)ES(0.003)VPVGPK 191.78 7.3951e-08 18405800.0 171155.0 146904.0 175437.0 138841.0 140936.0 144875.0 132463.0 134375.0 167809.0 111694.0 True False 168714.29831401736 146563.85281375455 161013.24706640418 149051.8302999983 132646.42157083692 138679.03397011987 139321.28599356324 140618.55306005504 148908.58331289055 131000.15907710038 1.2878938430503757 1.1188066781468116 1.2291072636914855 1.1377988496355458 1.0125668740048448 1.0586172944148875 1.0635199756632772 1.0734227656723205 1.1367053625121946 1.0 16.999209038104915 -6.012838229377237 4.592252980505351 1.0618531794915873 1.2012971977399347 0.6379157992863036 0.05214435164483846 0.12941346695406025 7.065726903050455 0.014785816073917725 0.020807391182493275 9.708715404463658e-07 6.012838229377237 0.1394440182483474 SAADSIS(ph)ESVPVGPK ddPTM_PC-9_AZD4547_30min_R2 1 SAADSISESVPVGPK 15 0 P45974-2;P45974 P45974-2 USP5 Ubiquitin carboxyl-terminal hydrolase 5 1 SAADS(0.18)IS(0.681)ES(0.138)VPVGPK 171.81 0.00011543 12190000.0 38213.0 46001.0 54805.0 69019.0 63750.0 64432.0 58519.0 72062.0 55821.0 68659.0 True False 50363.9391202232 60869.923651415935 54078.249891049156 53107.735882920235 54899.41290509995 60403.056854397575 63727.07763367562 60926.47372002274 58771.5840991699 66255.26930817321 0.7601499419761671 0.9187182285576652 0.8162105513376593 0.8015624483526006 0.8286044789848523 0.9116717430193327 0.9618416512241733 0.9195717466128672 0.8870476976828147 1.0 16.015747576791398 -6.8287424237749095 3.9929371028158007 0.9354397659943097 0.827991126074151 0.595718516270705 0.04604403925572082 0.16844249987010426 5.3072492518555645 0.01632616482041362 0.014619925993615574 1.4833976143355341e-07 6.8287424237749095 -0.10744863992015863 SAADSIS(ph)ESVPVGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SAADSISESVPVGPK 15 0 P45974-2;P45974 P45974-2 USP5 Ubiquitin carboxyl-terminal hydrolase 5 1 S(0.001)AADS(0.267)IS(0.56)ES(0.173)VPVGPK;SAADS(0.101)IS(0.847)ES(0.051)VPVGPK;SAADS(0.255)IS(0.664)ES(0.081)VPVGPK 204.82 8.3519e-13 22985000.0 93235.0 85404.0 90217.0 96128.0 109665.0 90893.0 95566.0 97912.0 89558.0 81757.0 True False 109017.84402481129 93882.3447046271 92368.11542987757 90742.25981118105 88176.93048678969 86126.41107201834 86513.29664207622 95341.91374633908 90867.61632290985 96578.8969119441 1.1287957049686372 0.9720792813592023 0.9564006049281581 0.9395661237870152 0.9130041169054258 0.8917725696385223 0.8957784713668329 0.9871919932287812 0.9408640937963754 1.0 16.559420365230693 -4.25833187054163 1.4031208306166285 0.9340077559999007 1.591205480496681 0.7336865413559814 0.03372067460817606 2.3781693833193325 1.5362886761514423 0.00990306959328054 3.1679170692638827 5.516557248445488e-05 4.25833187054163 0.6571977244967804 SAADSIS(ph)ESVPVGPK ddPTM_PC-9_Lapatinib_30min_R1 1 SAADSISESVPVGPK 15 0 P45974-2;P45974 P45974-2 USP5 Ubiquitin carboxyl-terminal hydrolase 5 1 SAADS(0.416)IS(0.491)ES(0.093)VPVGPK 111.07 0.00046052 13186000.0 133860.0 104890.0 129430.0 120560.0 122070.0 112930.0 112510.0 106360.0 148690.0 89038.0 True False 131951.13185308257 104647.1336494223 118788.76501424814 129426.38457637053 114890.08259885383 108100.24715268772 118335.21728434211 111301.87388626949 131942.96642488602 104428.09966432244 1.26355963842329 1.0020974621371446 1.1375172525027955 1.2393827426947681 1.1001835997031524 1.0351643618927202 1.1331740945657656 1.0658230327281868 1.2634814465551742 1.0 16.672150441054377 SAAPS(ph)SPGSPR ddPTM_PC-9_AZD4547_30min_R2 2 SAAPSSPGSPR 11 0 Q9H211;H3BSY1 Q9H211 CDT1 DNA replication factor Cdt1 1 SAAPS(0.5)S(0.5)PGSPR;SAAPS(0.494)S(0.494)PGS(0.013)PR 144.7 1.2704e-05 0.0 20310.0 20281.6 24618.0 32495.0 23472.0 28002.0 25778.0 30847.0 23429.0 20358.8 True False 26768.157525756527 26837.230571695345 24291.54923488455 25003.779792745372 20213.317956211842 26251.03051336047 28072.192061396967 26080.304943542284 24667.409108748525 19646.044608736443 1.3625214672399215 1.3660373426903978 1.2364600467252471 1.2727131741127364 1.0288746848932195 1.336199272482912 1.4288979089925042 1.3275091990753485 1.2555916267124385 1.0 14.261951259576996 -5.2568935905578185 23.35264144586056 1.2518904257992638 1.3642794419080595 0.13347550825077847 0.1257116551716213 348.35742699131225 1789534.4012188762 0.03297787954986516 0.08104153601747625 5.534857058972411e-06 5.2568935905578185 0.1123890161087957 SAAPS(ph)SPGSPR ddPTM_PC-9_Lapatinib_30min_R1 2 SAAPSSPGSPR 11 0 Q9H211;H3BSY1 Q9H211 CDT1 DNA replication factor Cdt1 1 SAAPS(0.482)S(0.482)PGS(0.035)PR;SAAPS(0.492)S(0.492)PGS(0.015)PR 99.539 0.004520199999999999 3540200.0 16602.5 23380.0 21888.0 20735.8 24156.0 22318.8 21703.3 22081.3 23350.5 19367.0 True False 16365.745305474382 23325.865046462925 20088.453130123344 22260.779904601033 22735.191572523247 21364.276951663927 22826.99067893751 23107.277809748837 20720.520798334135 22714.560145094623 0.7204958053748043 1.0269124692471898 0.8843866225805651 0.980022494928585 1.0009082908626377 0.9405542883152725 1.0049497121284634 1.0172892480481963 0.9122131648588795 1.0 14.471329748222345 -4.75387138216532 24.999926769539346 0.9728068629392023 0.7204953568273083 0.7427288390122773 0.044777748024800446 132.5534082171699 437837.4980470613 0.01065526312026585 0.1099219234285657 1.7624979390766013e-05 4.75387138216532 -0.252311506111894 SAAQAAAQT(ph)NSNAAGK ddPTM_PC-9_AZD4547_30min_R2 2 SAAQAAAQTNSNAAGK 16 0 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 SAAQAAAQT(0.999)NS(0.001)NAAGK;SAAQAAAQT(0.999)NS(0.001)NAAGK 234.38 4.1454999999999997e-94 0.0 8506.3 9710.0 12871.8 16628.4 15778.0 14533.400000000001 8783.3 12149.8 9016.5 11575.2 True False 11211.126457968616 12848.567610600834 12701.111521715284 12794.979286219028 13587.497048104573 13624.624200516853 9564.996684493293 10272.327584628978 9493.09378245042 11169.955771216675 1.0036858415194474 1.1502791840689015 1.1370780495339265 1.1454816427465002 1.2164324842823053 1.2197563248751169 0.8563146426363546 0.9196390563245781 0.8498774728287394 1.0 13.447335852857455 -7.2653373399686405 24.999030810365003 0.8997610377771599 1.1485187267558703 0.7499599812723317 0.06754688096135059 165.29060332094357 1060062.021307668 0.027804189965345196 0.01954890812899408 5.42828523475383e-08 7.2653373399686405 0.24875768897871042 SAAQAAAQT(ph)NSNAAGK ddPTM_PC-9_Lapatinib_30min_R1 2 SAAQAAAQTNSNAAGK 16 0 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 SAAQAAAQT(0.99)NS(0.01)NAAGK;S(0.001)AAQAAAQT(0.999)NSNAAGK 190.25 4.878899999999999e-39 0.0 12479.5 14736.4 12682.0 10197.3 13544.3 11736.9 11814.4 13772.8 12048.7 8102.9 True False 12301.540041539985 14702.278771201722 11639.334913935694 10947.243459195595 12747.650903118338 11234.94014705022 12426.091823696834 14412.73456807836 10691.648527564223 9503.475468564424 1.294425400710613 1.5470423236040214 1.2247450895660499 1.1519199997313472 1.3413672656161413 1.1821927866508555 1.3075313199681353 1.516575132513655 1.1250251092802874 1.0 13.214239495402607 -8.514893551443915 22.858783401636508 0.9999999807071597 1.3154311822277824 0.4357088935143546 0.12165166895817238 142.0127249116154 406530.11051607697 0.12016470745129477 0.031026394044621274 3.0556699871055823e-09 8.514893551443915 0.31543120152062276 SAAQAAAQTNS(ph)NAAGK ddPTM_PC-9_AZD4547_30min_R2 4 SAAQAAAQTNSNAAGK 16 0 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 SAAQAAAQT(0.001)NS(0.999)NAAGK;SAAQAAAQT(0.002)NS(0.998)NAAGK;SAAQAAAQT(0.001)NS(0.999)NAAGK;SAAQAAAQT(0.001)NS(0.999)NAAGK 233.38 7.053199999999999e-37 11880300.0 27989.699999999997 34946.8 37896.3 59666.0 42407.0 36299.7 35240.2 53823.0 39035.0 44207.5 True False 36889.842378073205 46242.669678078826 37393.77030099746 45910.925530510685 36519.520048103106 34029.87402063535 38376.50953068671 45505.89207949804 41098.310408468045 42659.808880715755 0.8647446705920231 1.083986799082513 0.8765573799347518 1.0762102957114885 0.8560638457199383 0.7977033867120407 0.8995940332971042 1.0667157981588813 0.9633964962990357 1.0 15.38058988185566 -7.748882869294424 24.993513713040954 1.011292121542994 0.9251962624102285 0.16594359359233712 0.0901234203562248 419.6086095022213 835227.5747046681 0.043920486492830334 0.025137587861585278 1.782859545922214e-08 7.748882869294424 -0.08609585913276552 SAAQAAAQTNS(ph)NAAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SAAQAAAQTNSNAAGK 16 0 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 SAAQAAAQTNS(1)NAAGK;SAAQAAAQT(0.001)NS(0.999)NAAGK 214.3 6.209e-22 6195400.0 19161.7 19684.0 16618.1 15888.8 21364.4 17290.6 18817.5 18751.7 14041.400000000001 13969.5 True False 22405.397349173814 21638.097432975967 17014.33852849521 14998.602048184626 17178.199185628655 16383.85049763831 17034.970173097834 18259.487744068465 14246.728911281036 16502.059767498853 1.3577333778236402 1.3112361570519 1.031043322361812 0.9088927236662105 1.0409730317097428 0.99283669605334 1.0322935689912214 1.1064974919089132 0.8633303425151969 1.0 14.010358490741234 -5.2574351443906036 3.974502266121804 0.9980766931825545 1.3464077860634918 0.8173132563638774 0.06415797947258524 0.07912945312505476 2.9618506210090803 0.016463773153270134 0.04349609904014841 5.527959538737623e-06 5.2574351443906036 0.3483310928809372 SAAQAAAQTNS(ph)NAAGK ddPTM_PC-9_Lapatinib_30min_R1 4 SAAQAAAQTNSNAAGK 16 0 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 SAAQAAAQT(0.004)NS(0.996)NAAGK;SAAQAAAQT(0.005)NS(0.995)NAAGK;SAAQAAAQT(0.05)NS(0.95)NAAGK;SAAQAAAQT(0.002)NS(0.998)NAAGK 178.07 7.528e-06 13174800.0 45597.4 41301.8 35915.4 30529.699999999997 40057.299999999996 32874.1 41970.6 34248.5 34993.299999999996 35918.399999999994 True False 44947.17271446096 41206.168219675055 32962.57444945323 32774.95598209367 37701.20836968191 31468.151376270016 44143.63230427699 35839.81034029621 31051.986058214836 42126.8475817404 1.066948402138284 0.9781450686458578 0.7824600306371045 0.7780063751150407 0.8949449231046485 0.7469856678739397 1.0478740954595127 0.8507593707493729 0.7371068057718638 1.0 15.362452340349881 -5.045202533893634 4.28059285524881 0.8515935876981011 1.052830172115545 0.33246503971107066 0.0985789462529317 0.2143845494183607 8.451927685962685 0.024899304088904683 0.08394243044218783 9.011507865549576e-06 5.045202533893634 0.20123658441744396 SAAQAAAQTNSNAAGK ddPTM_PC-9_Lapatinib_30min_R1 2 SAAQAAAQTNSNAAGK 16 0 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 ; 218.28 1.5266e-21 5002900.0 10280.3 13905.900000000001 14289.8 13177.199999999999 13929.9 11133.900000000001 16494.9 10614.0 11442.8 11243.2 False True 10133.701036823868 13873.701742925945 13114.947804223171 14146.295245850577 13110.570669237117 10657.729051388562 17348.925211834434 11107.16518831201 10153.991365974087 13186.5721393777 0.7684863761191312 1.0521082807787734 0.9945683886306855 1.0727803326238936 0.9942364498265908 0.80822589363937 1.3156508779129283 0.8423087570380652 0.7700250875397913 1.0 13.686781963074472 SAAQPST(ph)SPAEVQSLKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SAAQPSTSPAEVQSLKK 17 1 Q14789-4;Q14789-3;Q14789;Q14789-2 Q14789-4 GOLGB1 Golgin subfamily B member 1 1 SAAQPS(0.008)T(0.496)S(0.496)PAEVQSLKK;S(0.001)AAQPS(0.152)T(0.522)S(0.325)PAEVQSLKK 99.34299999999999 0.0010756 12312300.0 72223.0 50461.0 55859.0 55245.0 77850.0 56542.0 61725.0 49081.0 59424.0 42982.0 True False 84448.92743072784 55470.434594868944 57190.89040643719 52149.801756706554 62595.851350901 53576.8379834977 55877.96114969915 47792.675755618104 60292.96358083698 50774.29635467524 1.6632220137690175 1.0924904642181474 1.1263748493320305 1.0270905852130958 1.2328255799676333 1.0551960702566074 1.1005167015880066 0.9412769686017993 1.1874701947550528 1.0 15.631810720911751 -4.7613619515800645 8.126844039275063 1.0862390155994621 1.669877785934725 0.819192973713056 0.08152520498007441 0.034968381037869235 21.525550555776338 0.01918857577918832 0.11203426046846492 1.7323596053285417e-05 4.7613619515800645 0.5836387703352628 SAAQPSTS(ph)PAEVQSLKK ddPTM_PC-9_AZD4547_30min_R2 1 SAAQPSTSPAEVQSLKK 17 1 Q14789-4;Q14789-3;Q14789;Q14789-2 Q14789-4 GOLGB1 Golgin subfamily B member 1 1 SAAQPS(0.198)T(0.198)S(0.603)PAEVQSLKK 102.07 0.00045828 16025000.0 25675.0 26941.0 40127.0 44542.0 37706.0 27316.0 35231.0 32224.0 27717.0 29182.0 True False 33839.11592682415 35649.151390030565 39594.88976148396 34273.53006704 32471.172752936454 25607.926201805392 38366.49074850947 27244.521233854375 29182.064034623003 28160.34706230949 1.2016583407849852 1.265934376133605 1.406051199364611 1.2170847891613008 1.1530814119971085 0.9093611717619658 1.3624296129453652 0.9674781767984358 1.0362821157726783 1.0 14.781377494135004 -6.279273138603778 2.8331507987345668 1.0705610829344019 1.2884836472432675 0.40079102406371947 0.12431812711422251 0.2859481722960246 4.602662091170541 0.039903580860732084 0.04940883919219727 5.256865450562799e-07 6.279273138603778 0.21792256430886559 SAAQPSTS(ph)PAEVQSLKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAAQPSTSPAEVQSLKK 17 1 Q14789-4;Q14789-3;Q14789;Q14789-2 Q14789-4 GOLGB1 Golgin subfamily B member 1 1 SAAQPS(0.112)T(0.336)S(0.552)PAEVQSLKK 115.38 7.0614e-05 5398300.0 37117.0 31522.0 30777.0 29762.0 39563.0 31567.0 34099.0 25966.0 26875.0 27110.0 True False 43400.17500583377 34651.2958383595 31510.84040242247 28094.531629705867 31810.91415537182 29911.57094947246 30868.895864618735 25284.420013251165 27267.996032495157 32024.82839735807 1.3552039832136658 1.0820134743085184 0.9839503278969013 0.8772734479983525 0.9933203625845534 0.9340119040868945 0.9639051139198394 0.7895255424799414 0.8514642356286495 1.0 14.966903219563871 SAAQPSTS(ph)PAEVQSLKK ddPTM_PC-9_Lapatinib_30min_R1 2 SAAQPSTSPAEVQSLKK 17 1 Q14789-4;Q14789-3;Q14789;Q14789-2 Q14789-4 GOLGB1 Golgin subfamily B member 1 1 SAAQPS(0.059)T(0.059)S(0.882)PAEVQSLKK;SAAQPS(0.309)T(0.309)S(0.382)PAEVQSLKK 103.4 0.00039828 10055000.0 90914.0 68154.0 56201.0 39019.0 43960.0 46007.0 33715.0 33145.0 47995.0 18343.9 True False 89617.54968841426 67996.19360036921 51580.37072213368 41888.58742356828 41374.35922868531 44039.38785755515 35460.59773123804 34685.03770177143 42589.29769024418 21514.618673289693 4.165425892473477 3.160464734835677 2.3974568875892044 1.9469825637938347 1.9230812247698073 2.0469518203559827 1.6482094463176435 1.6121613972564968 1.9795515940572357 1.0 14.393029649627481 -1.5228787454088808 0.4760932526919739 1.5980094565125271 73.21359525772137 0.9160833654953325 0.24453313953499428 24.494251114455263 0.27725926640324955 0.1376479816925237 1732.1725964796929 0.02999999999112055 1.5228787454088808 71.61558580120884 up SAAREFS(ph)HMLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAAREFSHMLSR 12 1 P78357 P78357 CNTNAP1 Contactin-associated protein 1 1 S(0.033)AAREFS(0.961)HMLS(0.007)R 61.423 0.02355 8684500.0 11238.0 12115.0 16336.0 14770.0 20132.0 17571.0 14860.0 15949.0 19908.0 14832.0 True False 13140.371439382496 13317.697134754308 16725.512194625 13942.484784986076 16187.279118771228 16649.545828022332 13452.353222916632 15530.355649362353 20199.116837764243 17520.924189952602 0.7499816389205005 0.7601024346872843 0.9546021667176819 0.7957619491888113 0.9238827212124944 0.9502664156020969 0.7677878790566826 0.886389067208467 1.1528568138744333 1.0 14.096791255464328 -1.5390650158308379 0.14186384565806712 1.0591991932735414 2.601048207409755e-15 0.3978787870616538 0.09512519551139431 83.51300775838381 0.7930729549955791 0.40527792639368637 17.962500586219505 0.028902471670189903 1.5390650158308379 -1.0591991932735387 SAAREFSHMLS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAAREFSHMLSR 12 1 P78357 P78357 CNTNAP1 Contactin-associated protein 1 1 S(0.005)AAREFS(0.266)HMLS(0.729)R 50.659 0.044697 5964100.0 10046.0 11354.0 12826.0 12936.0 15779.0 15541.0 10937.0 11390.0 14958.0 12169.0 True False 11746.589382455635 12481.150084028091 13131.820482875868 12211.237859077859 12687.218220499257 14726.002601633092 9900.96818297706 11091.024568702562 15176.732452244198 14375.143370249003 0.817145894124892 0.868245259373152 0.9135088356790699 0.8494689440350492 0.8825802911125673 1.0244073552762076 0.6887561346670282 0.7715418401778656 1.0557621625989606 1.0 13.811288724372778 -8.2732848558094 24.940444773684288 1.0278811132153314 0.8557976823854582 0.4112506756605844 0.08409679430344157 858.1669015442288 1806835.295816392 0.08148449454362562 0.021709624072431526 5.329851932996599e-09 8.2732848558094 -0.1720834308298732 SAAS(ph)PVVSSMPER ddPTM_PC-9_AZD4547_30min_R2 5 SAASPVVSSMPER 13 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 S(0.001)AAS(0.944)PVVS(0.01)S(0.045)MPER;S(0.002)AAS(0.995)PVVS(0.002)S(0.002)MPER;S(0.003)AAS(0.963)PVVS(0.017)S(0.017)MPER;S(0.002)AAS(0.932)PVVS(0.033)S(0.033)MPER;SAAS(0.962)PVVS(0.037)S(0.001)MPER 142.39 8.1343e-05 103934000.0 123799.0 132569.0 186415.0 228932.0 202190.0 157635.0 156822.0 196421.0 146214.0 163135.0 True False 163164.5068208339 175419.33672190944 183943.01529860296 176155.26436414156 174119.40855344528 147778.05853059012 170778.85419553105 166068.64775555185 153942.5735382029 157423.69330442924 1.0364672775482593 1.114313436813351 1.1684582634133103 1.1189882581619326 1.106055923975367 0.9387281890586432 1.0848357741504344 1.0549152053903654 0.9778869387882136 1.0 17.264293166745674 -6.619215044397261 10.877667224705652 1.0193543361883266 1.1139000096179807 0.5028600617274219 0.04811101961976703 0.34625029640474286 36.46373357230807 0.016072617981651303 0.01606871201333701 2.403172555179148e-07 6.619215044397261 0.09454567342965414 SAAS(ph)PVVSSMPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAASPVVSSMPER 13 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 S(0.001)AAS(0.858)PVVS(0.046)S(0.095)MPER 65.565 0.034744 26547000.0 48281.0 50283.0 59970.0 61707.0 70836.0 57250.0 64582.0 55975.0 49825.0 51420.0 True False 56454.01970678287 55274.76393122996 61399.912237491466 58249.75684679326 56956.19430048068 54247.709217134936 58464.32542681037 54505.71556041487 50553.59636536081 60742.038959503945 0.9294060698953512 0.9099919080438021 1.0108306090683936 0.958969403144793 0.9376734017515078 0.8930834418202737 0.9625018591454906 0.8973310164440353 0.8322670300722758 1.0 15.890407716559816 -6.55224408742112 6.275375491677911 0.9134763552398703 0.9529208900705298 0.10588115211756377 0.04790624314818304 0.37980331684761726 46.935541201693106 0.01585905481335913 0.01609284141735795 2.8038573373199107e-07 6.55224408742112 0.03944453483065957 SAAS(ph)PVVSSMPER ddPTM_PC-9_Lapatinib_30min_R1 4 SAASPVVSSMPER 13 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 S(0.001)AAS(0.97)PVVS(0.025)S(0.005)MPER;SAAS(0.892)PVVS(0.088)S(0.02)MPER;SAAS(0.454)PVVS(0.454)S(0.092)MPER;S(0.006)AAS(0.969)PVVS(0.018)S(0.006)MPER 94.781 0.0032418 56302500.0 138253.0 128799.0 148858.0 129035.0 137429.0 141337.0 119030.0 115498.0 134100.0 108840.0 True False 136281.4868675051 128500.77382888709 136619.46984849728 138524.66434814138 129345.69641580973 135292.345982639 125192.79098173702 120864.45872617852 118996.24586439716 127652.8489798164 1.0675945578704085 1.0066424279273607 1.0702422307088393 1.085167040573015 1.0132613368955126 1.0598458793820615 0.9807285304030439 0.9468214747427125 0.9321863696376416 1.0 16.961866210875037 -7.388697778567572 3.4877720955001443 0.9554692288437172 1.0493904260959748 0.6890940106214931 0.028275707933145683 0.13860875178762258 3.0870192277372706 0.012800859817155907 0.008154574445365907 4.086036308312469e-08 7.388697778567572 0.09392119725225756 SAAS(ph)REDLVGPEVGASPQSGR ddPTM_PC-9_AZD4547_30min_R2 2 SAASREDLVGPEVGASPQSGR 21 1 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 S(0.132)AAS(0.868)REDLVGPEVGASPQSGR;SAAS(1)REDLVGPEVGASPQSGR 218.22 1.9118999999999998e-31 13676200.0 12493.5 13834.0 20159.2 25922.4 25531.4 26271.0 24148.0 22690.5 22304.1 19413.2 True False 16466.173119056577 18305.56996138536 19891.875836212723 19946.391177087626 21986.80581404343 24628.270217002104 26297.12521912538 19184.20460081843 23483.049191277387 18733.54977691821 0.8789670572389173 0.9771543663304982 1.0618316375213466 1.0647416754759298 1.1736593478473358 1.3146611566029431 1.403744913925834 1.0240560293840026 1.2535290679511835 1.0 14.193336677972855 -5.610098114751111 1.0997630671601424 1.21128492683718 0.8959452925808074 0.441204648906494 0.1175852754695063 0.5840843955797721 1.2702069263127456 0.043109998836821865 0.15499606049581996 2.4541544164660777e-06 5.610098114751111 -0.31533963425637257 SAAS(ph)REDLVGPEVGASPQSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SAASREDLVGPEVGASPQSGR 21 1 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 S(0.11)AAS(0.521)REDLVGPEVGAS(0.014)PQS(0.355)GR;S(0.037)AAS(0.963)REDLVGPEVGASPQSGR;SAAS(1)REDLVGPEVGASPQSGR;S(0.03)AAS(0.867)REDLVGPEVGAS(0.081)PQS(0.022)GR 182.0 1.2065e-12 15232100.0 18072.7 27127.9 32752.5 31951.6 44343.4 29784.2 38890.5 31368.0 33238.2 28886.0 True False 21132.051157904236 29820.978629954712 33533.44381454794 30161.455440484868 35654.62909176038 28222.264119912514 35206.51029716278 30544.623237143256 33724.245794503484 34122.803138549825 0.6192941146159987 0.8739310926148626 0.9827282851995222 0.8839090773996328 1.044891562600846 0.827079299590975 1.0317590308806912 0.8951381606347527 0.9883199119829614 1.0 15.058448546368982 -4.7689935173657245 2.7360058559892475 0.9514349708133172 0.5492259031995063 0.7033419559391034 0.06579192920337125 0.23616591033012543 2.322760384440118 0.015292674217746027 0.2215589615075132 1.7021839163932185e-05 4.7689935173657245 -0.4022090676138109 SAAS(ph)REDLVGPEVGASPQSGR ddPTM_PC-9_Lapatinib_30min_R1 4 SAASREDLVGPEVGASPQSGR 21 1 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 S(0.01)AAS(0.989)REDLVGPEVGASPQSGR;S(0.22)AAS(0.78)REDLVGPEVGASPQSGR;S(0.039)AAS(0.961)REDLVGPEVGASPQSGR;S(0.004)AAS(0.996)REDLVGPEVGASPQSGR 161.49 7.1567e-06 15937100.0 45616.7 58204.9 70627.2 54076.6 74341.3 72466.0 60340.6 63379.5 74822.4 52651.6 True False 44966.19749292177 58070.13013014841 64820.50424487606 58053.57355824935 69968.6908946193 69366.7981064967 63464.74101917671 66324.34294824021 66395.11339719818 61752.358906152964 0.7281697135045212 0.9403710426414552 1.049684666190418 0.9401029302617447 1.1330529251676515 1.1233060458777882 1.0277298251169014 1.0740373991062502 1.0751834354716872 1.0 15.914206627456613 -4.174342094935902 0.9798862957461963 1.0657419814091618 7.905856276351089e-11 0.7814060054839104 0.05278741530040402 2.4798283654195212 0.8247330877477222 0.017199159756636516 3.7147866717445823 6.693571472700883e-05 4.174342094935902 -1.0657419813301032 SAAS(ph)REDLVGPEVGASPQSGRK ddPTM_PC-9_AZD4547_30min_R2 1 SAASREDLVGPEVGASPQSGRK 22 2 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 S(0.203)AAS(0.79)REDLVGPEVGAS(0.002)PQS(0.005)GRK 51.611000000000004 0.009409200000000001 4013000.0 10164.0 6757.8 11901.0 24036.0 18775.0 13258.0 11638.0 18320.0 10416.0 15570.0 True False 13395.940575666624 8942.126694018361 11743.18496402474 18494.871552498156 16168.415330090222 12428.97516413588 12673.759454206609 15489.064951719609 10966.568495314543 15024.899039139162 0.8915827348171075 0.5951538623137859 0.7815816221749171 1.2309481417691979 1.0761080848511697 0.8272252034279218 0.8435171125737388 1.0308931135824153 0.729892990744706 1.0 13.875067676228165 -5.544480465414973 24.99876543869948 0.9617703148416097 0.7296180108254504 0.2889335385981946 0.14897509108235096 267.27335868078876 309302.9265432592 0.04125061543889207 0.07145540076777666 2.8544309033275024e-06 5.544480465414973 -0.23215230401615927 SAASREDLVGPEVGAS(ph)PQSGRK ddPTM_PC-9_Lapatinib_30min_R1 1 SAASREDLVGPEVGASPQSGRK 22 2 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 S(0.001)AAS(0.001)REDLVGPEVGAS(0.921)PQS(0.076)GRK 76.90899999999999 0.006806399999999999 0.0 12027.0 4223.9 6569.9 4553.7 4585.7 4972.1 3541.0 4324.1 5597.6 3578.3 True False 11855.492774518321 4214.1198190656405 6029.748182547398 4888.594288697891 4315.97814183308 4759.454873531204 3724.3356537539344 4525.013471903144 4967.139342658836 4196.8043872149565 2.824885717960696 1.0041258610726373 1.4367474931441353 1.164837299443926 1.0283963091015564 1.1340664072955824 0.88742178813472 1.078204522871744 1.183552742603541 1.0 12.03507550552906 -4.759317379985383 24.999997565763195 1.1088040132076369 2.8248879138481193 0.9316039281334018 0.140042924785181 13.49420881758684 158941.31308274498 0.03601105055903203 0.23081339605145784 1.740534435644157e-05 4.759317379985383 1.7160839006404824 SAATWDER ddPTM_PC-9_AZD4547_30min_R2 1 SAATWDER 8 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 106.04 0.017658 4205300.0 27058.0 21346.0 37845.0 53191.0 40839.0 33502.0 26866.0 45994.0 30591.0 37808.0 False True 35661.881158637116 28245.677056218898 37343.15057251629 40928.63674275795 35169.20978245294 31407.114643904097 29257.0219536617 38886.6841369755 32207.977807235744 36484.35342785958 0.9774568495273257 0.7741860387376468 1.0235387793387871 1.1218134048527415 0.9639532149581033 0.8608379125041999 0.8019060009247946 1.0658455059061425 0.882788778782129 1.0 15.154990266235613 -6.550687472282865 24.64572406326246 0.9181487054524227 0.9734048107726931 0.05319437127813964 0.10526360282285628 641.6360380153167 568650.3194979577 0.03678221080537835 0.03678295242434347 2.8139250634032454e-07 6.550687472282865 0.05525610532027048 SAATWDER ddPTM_PC-9_Lapatinib_30min_R1 1 SAATWDER 8 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 107.9 0.017521000000000002 3943100.0 36226.0 37914.0 42995.0 37089.0 39181.0 37706.0 35197.0 34093.0 38412.0 28682.0 False True 35709.41059696523 37826.21246242921 39460.117065499515 39816.64878527704 36876.450612809815 36093.40227697907 37019.32843975634 35677.08524261556 34085.636063707876 33639.64548363731 1.0615275542762386 1.1244533620554442 1.1730241653317466 1.1836227229161582 1.0962199536480526 1.0729424094119926 1.1004672584246746 1.0605666239844675 1.0132578858563626 1.0 15.037874881168268 -7.788266320355176 0.7762223902157207 0.997660541553276 1.1325712456245296 0.6256284490046877 0.03511210739952979 0.44852634359402505 0.5135969021478133 0.03523815065655829 0.01604517847764304 1.6282972134061485e-08 7.788266320355176 0.1349107040712536 SAAVETAS(ph)LSPSLVPAR ddPTM_PC-9_AZD4547_30min_R2 1 SAAVETASLSPSLVPAR 17 0 Q2KHT3;Q2KHT3-3 Q2KHT3 CLEC16A Protein CLEC16A 1 SAAVET(0.007)AS(0.568)LS(0.407)PS(0.018)LVPAR 124.2 4.1031999999999996e-05 26086000.0 19773.0 21526.0 22012.0 36146.0 30218.0 29376.0 17413.0 33131.0 25943.0 24125.0 True False 26060.402696050383 28483.85853612703 21720.106497614703 27813.09815013308 26022.752300647993 27539.11407615444 18962.723266549216 28011.36522464093 27314.29401631581 23280.391093078488 1.1194142998653671 1.2235128878309776 0.9329785917588096 1.1947006405060874 1.1177970420086645 1.1829317628749854 0.814536284666929 1.2032171243450034 1.1732747060437763 1.0 14.506827674191932 SAAVETAS(ph)LSPSLVPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SAAVETASLSPSLVPAR 17 0 Q2KHT3;Q2KHT3-3 Q2KHT3 CLEC16A Protein CLEC16A 1 SAAVET(0.006)AS(0.577)LS(0.415)PS(0.002)LVPAR;SAAVET(0.009)AS(0.978)LS(0.006)PS(0.006)LVPAR 147.53 8.047e-05 16963600.0 24196.0 20209.4 32212.0 34030.0 38127.0 33915.0 39133.0 34744.0 40952.0 35866.0 True False 28291.904907216485 22215.655672728317 32980.05624469028 32123.409426748574 30656.288046959562 32136.437696054705 35426.038941614854 33832.00681431096 41550.84552642763 42368.221884900224 0.6677623853102872 0.5243471329309158 0.7784149246169844 0.7581958363515171 0.7235679639858872 0.7585033373210297 0.8361464646275486 0.7985231692333182 0.9807077965015117 1.0 15.370694962306816 -6.3184171989772056 0.19572333526611727 1.0675738750683714 0.4138769913456765 0.75638398956578 0.06514269407350763 3.6362183548756914 0.2654537672509289 0.20223707553576029 0.6520052135010351 4.803776585848114e-07 6.3184171989772056 -0.6536968837226949 SAAVETASLS(ph)PSLVPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAAVETASLSPSLVPAR 17 0 Q2KHT3;Q2KHT3-3 Q2KHT3 CLEC16A Protein CLEC16A 1 SAAVETAS(0.025)LS(0.757)PS(0.218)LVPAR 164.8 2.7784e-05 3013200.0 9944.9 14162.0 17910.0 17230.0 22557.0 23745.0 21783.0 20606.0 20876.0 16444.0 True False 11628.375149271656 15567.909766602592 18337.04232405324 16264.65896041368 18137.11777677938 22499.7703993165 19719.556544737075 20065.11433386171 21181.272006488165 19425.167029367632 0.5986242039356202 0.8014299049818461 0.9439837658193967 0.8372982809272226 0.9336917283315539 1.1582793787719086 1.0151550570929133 1.0329442369029098 1.0904035972748956 1.0 14.245639383402736 -4.176988013871429 0.5053592984891382 1.0590002168591002 4.707290014997407e-12 0.7989875624648347 0.06865413349455211 3.558327375183141 0.44206754406689464 0.04249641431660496 2.540715610994299 6.652915173828214e-05 4.176988013871429 -1.0590002168543928 SAAVETASLS(ph)PSLVPAR ddPTM_PC-9_Lapatinib_30min_R1 3 SAAVETASLSPSLVPAR 17 0 Q2KHT3;Q2KHT3-3 Q2KHT3 CLEC16A Protein CLEC16A 1 SAAVETAS(0.038)LS(0.837)PS(0.125)LVPAR;SAAVETAS(0.001)LS(0.499)PS(0.499)LVPAR;SAAVET(0.002)AS(0.228)LS(0.749)PS(0.021)LVPAR 200.71 1.2083e-12 36057000.0 46435.1 52991.0 55717.3 53885.8 62284.5 60736.6 58478.1 66526.3 69138.7 49830.6 True False 45772.92695884557 52868.30259525732 51136.438668997725 57848.74148975926 58621.048166038454 58139.03720192982 61505.809882459136 69617.35476419849 61351.571543212485 58443.75281489916 0.7831962314914281 0.904601433838443 0.8749684304318225 0.9898190773781349 1.0030336065464656 0.9947861730588311 1.0523932314418276 1.1911855657984172 1.0497541411743845 1.0 15.834761199607566 -5.627993024995271 0.5836520142402594 1.0866214793319415 0.7570783670565077 0.7289273288767186 0.054904958990395436 0.8507378511690368 0.4247726562100768 0.03457839333157185 0.16875600315594397 2.3550871075674744e-06 5.627993024995271 -0.32954311227543387 SAAVETASLSPS(ph)LVPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAAVETASLSPSLVPAR 17 0 Q2KHT3;Q2KHT3-3 Q2KHT3 CLEC16A Protein CLEC16A 1 SAAVETAS(0.002)LS(0.309)PS(0.688)LVPAR 144.15 0.00011225 11974000.0 17078.0 21373.0 19362.0 25150.0 31981.0 31111.0 27107.0 31970.0 32667.0 28157.0 True False 19968.96809412476 23494.770190763815 19823.663510793907 23740.92703740013 25714.552627529425 29479.48439221458 24539.228722315012 31130.821375014988 33144.69307510773 33261.641209310634 0.6003602759245393 0.706362324183424 0.595991742741932 0.7137629465726588 0.773099332823402 0.8862907337225036 0.7377636168910982 0.9359376219325225 0.9964839938754987 1.0 15.021571735971293 -7.008250807416475 0.45829011766555067 1.0196746644061854 0.5978959310673941 0.8252914080696405 0.060066918302317134 0.4546899424498835 0.20711638626104148 0.06011786603965567 0.07193666165593428 9.811811419444978e-08 7.008250807416475 -0.42177873333879123 SACMLSSPES(ph)SLTPPLSTNLHLESELDALASLENHVK ddPTM_PC-9_AZD4547_30min_R2 1 SACMLSSPESSLTPPLSTNLHLESELDALASLENHVK 37 0 H0Y612;Q9UPN9-2;Q9UPN9 H0Y612 TRIM33 E3 ubiquitin-protein ligase TRIM33 1 S(0.007)ACMLS(0.022)S(0.073)PES(0.307)S(0.307)LT(0.276)PPLS(0.005)T(0.003)NLHLESELDALASLENHVK 72.37 4.296e-07 1956600.0 1520.8 1200.9 3869.2 7408.4 5100.1 6416.0 3236.1 4372.8 3106.9 6501.4 True False 2004.382765394905 1589.067440120549 3817.8918799096314 5700.507838639017 4392.039149134121 6014.806505739614 3524.1066308436193 3697.0842369475668 3271.1243911379406 6273.787964872147 0.31948525780879683 0.25328676216314117 0.6085465274386964 0.9086229675846539 0.700061776669181 0.9587200809809627 0.5617191161983168 0.5892905940793791 0.5213954327837412 1.0 12.615121055922552 -5.372828341225481 3.94862657910596 0.7319340991420636 0.28613532633975963 0.5640875117022051 0.15940800630375704 0.1680563335707275 4.529995555846901 0.043471987171236466 0.09857570586196711 4.238104478143962e-06 5.372828341225481 -0.445798772802304 SADAGSFS(ph)PTPGQIGGAVK ddPTM_PC-9_AZD4547_30min_R2 1 SADAGSFSPTPGQIGGAVK 19 0 O00443 O00443 PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 1 SADAGSFS(0.839)PT(0.161)PGQIGGAVK 149.74 2.4771e-14 0.0 15075.0 12634.0 13799.0 22011.0 17988.0 15619.0 17277.0 23903.0 12664.0 15924.0 True False 19868.536420520897 16717.693428664363 13616.01624389356 16936.704016560045 15490.67669548137 14642.341460901976 18814.619530016123 20209.340586296603 13333.393185931584 15366.50560688837 1.292976876383294 1.0879307147859494 0.8860840969458851 1.1021831800827768 1.00808063275865 0.9528738566521089 1.2243915442676871 1.315155254115635 0.8676919481260984 1.0 13.907501508353114 -7.26128839800163 24.99989340623988 1.1280726173920348 1.048848490074707 0.009765125839484301 0.15159618079958065 46.44985030665444 7692377.0120878685 0.060851445149147136 0.04391484572171062 5.479129964664673e-08 7.26128839800163 -0.07922412731732775 SADAGSFS(ph)PTPGQIGGAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SADAGSFSPTPGQIGGAVK 19 0 O00443 O00443 PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 1 SADAGS(0.027)FS(0.801)PT(0.172)PGQIGGAVK 170.89 6.2390999999999995e-28 0.0 8118.6 8066.4 8981.3 11527.0 11374.0 11805.0 9221.9 11434.0 12521.0 10230.0 True False 9492.918630340864 8867.178883019566 9195.44825376993 10881.179561038229 9145.346348942176 11185.925018485204 8348.334871225763 11133.869615324416 12704.095937595232 12084.618019364558 0.7855373347448203 0.7337574815199518 0.760921713788141 0.9004156807937228 0.7567757900404918 0.925633313403926 0.6908232314706412 0.9213257380153308 1.0512616879770642 1.0 13.560884251471489 -7.98392585245823 5.805443738440225 1.0150032793148516 0.7975637707081208 0.6523100350723695 0.0687435818643781 0.0940088642636452 10.889408011037158 0.03957526077777926 0.017541568566603247 1.0377055692296102e-08 7.98392585245823 -0.21743950860673078 SADAGSFSPT(ph)PGQIGGAVK ddPTM_PC-9_Lapatinib_30min_R1 1 SADAGSFSPTPGQIGGAVK 19 0 O00443 O00443 PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 1 SADAGS(0.006)FS(0.381)PT(0.613)PGQIGGAVK 92.439 0.0030954999999999997 0.0 11282.0 10119.0 14044.0 10805.0 11715.0 11532.0 9721.8 12108.0 10491.0 9551.5 True False 11121.116611134592 10095.5700772095 12889.356531407728 11599.635744423367 11025.946732576165 11038.80324240498 10225.147234867272 12670.581882427166 9309.393104872415 11202.464048426258 0.9927384335321215 0.9011919193463285 1.1505822715153857 1.0354539585469953 0.9842429919804214 0.9853906421557077 0.9127587636671523 1.1310531172119362 0.8310129864848989 1.0 13.451528476069738 -6.373577151143096 5.402164826968525 0.9774652791008472 1.0206422014617638 0.05773469743314941 0.09053125352051543 0.8423937243227699 34.70408306512116 0.02790640959949234 0.03169967129618784 4.2308034405599156e-07 6.373577151143096 0.043176922360916525 SADCSVPS(ph)PALDK ddPTM_PC-9_AZD4547_30min_R2 2 SADCSVPSPALDK 13 0 O43439-2;O43439-5;O43439;O43439-4;Q68DC6 O43439-2 CBFA2T2;DKFZp313F2116 Protein CBFA2T2 1 SADCS(0.013)VPS(0.987)PALDK;SADCS(0.222)VPS(0.778)PALDK 134.04 0.00023785 0.0 49765.0 51880.0 54708.0 70625.0 63405.0 57188.0 52898.0 65591.0 61768.0 58071.0 True False 65589.23482369633 68649.19543130492 53982.53617442779 54343.497395372935 54602.31019996645 53612.02531955065 57605.81952299551 55455.41808123587 65032.930378128716 56037.95196543678 1.1704431108429982 1.2250482578957655 0.9633210044457596 0.9697623751291097 0.9743809023149916 0.9567092200767365 1.0279786734269976 0.9896046542785822 1.1605158307398507 1.0 15.774116609706114 -5.259489869959606 24.99793994254055 1.001616205264764 1.1977456999895228 0.643168409889582 0.057289978681533314 98.65341797004008 1264978.5537636133 0.01485850155879374 0.035452747486282514 5.5018675362112845e-06 5.259489869959606 0.19612949472475893 SADCSVPS(ph)PALDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SADCSVPSPALDK 13 0 O43439-2;O43439-5;O43439;O43439-4;Q68DC6 O43439-2 CBFA2T2;DKFZp313F2116 Protein CBFA2T2 1 SADCS(0.001)VPS(0.999)PALDK 105.0 0.0027481 0.0 17478.0 17544.0 19172.0 16430.0 22799.0 16637.0 20335.0 13474.0 17159.0 16905.0 True False 20436.680193764663 19285.652375743248 19629.13319021488 15509.4803667787 18331.699613990917 15764.52643223535 18408.721587349228 13120.321776883076 17409.917913361296 19969.742680093626 1.023382249894311 0.9657436595298597 0.9829437216425291 0.7766489841773958 0.9179737519735016 0.7894206092074412 0.9218306856652456 0.6570100570179987 0.8718148346856751 1.0 14.285528122619537 -5.744711859737453 24.188194608355 0.837097173706439 0.9881953998778384 0.3400726586122197 0.09032808219652555 171.1880523181987 247536.7566031428 0.023187141927911825 0.040004001053304275 1.8000648034787664e-06 5.744711859737453 0.15109822617139945 SADEADELPPDLPKPPS(ph)PAPSSEDPGLAQPR ddPTM_PC-9_AZD4547_30min_R2 1 SADEADELPPDLPKPPSPAPSSEDPGLAQPR 31 1 Q8TBE0-3;Q8TBE0-2;Q8TBE0 Q8TBE0-3 BAHD1 Bromo adjacent homology domain-containing 1 protein 1 SADEADELPPDLPKPPS(0.854)PAPS(0.031)S(0.115)EDPGLAQPR 83.755 1.9262e-08 4577800.0 16626.0 12595.0 15491.0 16087.0 14230.0 16971.0 16475.0 13897.0 15166.0 17594.0 True False 21912.722157716766 16666.087441350923 15285.579218360415 12378.3906916724 12254.410127679555 15909.800687173794 17941.243083695994 11749.537971290787 15967.64379799735 16978.039415196825 1.2906509180384498 0.9816261485665607 0.9003147445092211 0.7290824569880938 0.7217800493919687 0.9370811492481951 1.0567323260916108 0.6920432733106937 0.9404880862571752 1.0 14.051382248965588 -4.73227767543758 1.994022775050453 0.8594872771246168 1.4540096901668458 0.5368753542232344 0.11685194552557931 0.6815094247687682 2.6653276879772068 0.03206564454971056 0.7834242118403597 1.8523469072251763e-05 4.73227767543758 0.594522413042229 SADEADELPPDLPKPPS(ph)PAPSSEDPGLAQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SADEADELPPDLPKPPSPAPSSEDPGLAQPR 31 1 Q8TBE0-3;Q8TBE0-2;Q8TBE0 Q8TBE0-3 BAHD1 Bromo adjacent homology domain-containing 1 protein 1 SADEADELPPDLPKPPS(0.775)PAPS(0.083)S(0.142)EDPGLAQPR 70.21300000000001 0.00065624 0.0 9796.2 10213.0 7269.6 10976.0 10793.0 9953.4 11217.0 8972.6 10180.0 9950.4 True False 11454.50317623053 11226.879144634395 7442.934834111529 10361.050304672126 8678.189128198776 9431.426182040716 10154.44455595262 8737.078757255533 10328.86324133212 11754.328752676944 0.9744923268052945 0.955127202995541 0.6332079858168393 0.8814667789781266 0.7382972954727334 0.8023789686750757 0.8638897864448478 0.7433073330763988 0.8787284632463435 1.0 13.520904533782007 -10.60145813092763 16.383286688809573 0.9999999999904985 0.824422463999799 0.20700434811888224 0.09920265064822992 0.0 0.0 0.09537960709705269 0.02313295262300354 2.5034669887465988e-11 10.60145813092763 -0.17557753599069947 SADEADELPPDLPKPPS(ph)PAPSSEDPGLAQPR ddPTM_PC-9_Lapatinib_30min_R1 1 SADEADELPPDLPKPPSPAPSSEDPGLAQPR 31 1 Q8TBE0-3;Q8TBE0-2;Q8TBE0 Q8TBE0-3 BAHD1 Bromo adjacent homology domain-containing 1 protein 1 SADEADELPPDLPKPPS(0.823)PAPS(0.041)S(0.137)EDPGLAQPR 72.848 8.1956e-06 5487600.0 43674.0 37115.0 29799.0 35048.0 42766.0 32444.0 34783.0 33499.0 33343.0 26874.0 True False 43051.200751169315 37029.06249783882 27349.04124746646 37625.54683670063 40250.58796119098 31056.44575065792 36583.89354547389 35055.48583411196 29587.56022264426 31519.135092645887 1.3658750668324688 1.1748121383723669 0.8676964379599235 1.1937366531824507 1.2770207000566565 0.9853203667985191 1.1606883703483895 1.1121969473804243 0.9387173897911841 1.0 14.943940326314847 -4.8619283756453235 3.986090746835791 1.080168130973737 1.3701487502324197 0.366943855593156 0.1187599330349843 0.24762437686077993 6.524695943352721 0.02994687406191318 0.1710739002117206 1.3742686023118566e-05 4.8619283756453235 0.2899806192586827 SADGS(ph)APAGEGEGVTLQR ddPTM_PC-9_AZD4547_30min_R2 2 SADGSAPAGEGEGVTLQR 18 0 Q01650 Q01650 SLC7A5 Large neutral amino acids transporter small subunit 1 1 S(0.003)ADGS(0.997)APAGEGEGVTLQR;S(0.004)ADGS(0.996)APAGEGEGVTLQR 125.61 4.422e-05 9448200.0 17679.2 30229.4 36793.0 39639.0 30850.1 21378.2 23265.3 41229.0 22575.6 23433.6 True False 23300.817849795905 40000.46238186374 36305.10077988086 30500.84096644512 26567.096126488217 20041.417774470494 25335.866629141885 34858.00539816851 23768.900126999153 22613.196796632717 1.0304079542289917 1.7688990522481158 1.6054829003781974 1.3488071253590708 1.1748491982541922 0.8862708777847287 1.1204018103674132 1.5414894988823138 1.0511074723649214 1.0 14.464877337876713 -6.1045987883487385 3.268177344874711 1.1435750703244825 1.4964536615586024 0.2952853678916334 0.23673990972090264 0.3222406344342677 6.496577275454381 0.07377678368777485 0.1007906517831878 7.859613892924951e-07 6.1045987883487385 0.3528785912341199 SADGS(ph)APAGEGEGVTLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SADGSAPAGEGEGVTLQR 18 0 Q01650 Q01650 SLC7A5 Large neutral amino acids transporter small subunit 1 1 SADGS(1)APAGEGEGVTLQR;S(0.02)ADGS(0.98)APAGEGEGVTLQR;SADGS(1)APAGEGEGVTLQR 217.65 1.2970999999999999e-27 12300900.0 32408.699999999997 32024.7 33574.2 24898.0 57139.0 25702.1 24450.1 30075.8 25865.4 20544.4 True False 37894.85280899762 35203.900572130915 34374.73625886255 23503.045780405108 45943.02312574353 24354.23663003885 22134.009524605237 29286.342117944212 26243.632542470736 24268.937090619078 1.5614549853378419 1.450574470595115 1.4164088081199802 0.9684414975672743 1.8930793282867902 1.0035147620640026 0.9120304462431906 1.206741853118263 1.0813671997450172 1.0 14.566823303544359 SADGS(ph)APAGEGEGVTLQR ddPTM_PC-9_Lapatinib_30min_R1 3 SADGSAPAGEGEGVTLQR 18 0 Q01650 Q01650 SLC7A5 Large neutral amino acids transporter small subunit 1 1 SADGS(1)APAGEGEGVTLQR;SADGS(1)APAGEGEGVTLQR;S(0.028)ADGS(0.972)APAGEGEGVTLQR 199.41 4.1833999999999993e-54 9626600.0 63563.0 73277.0 35735.9 16759.1 34567.5 23425.9 19599.5 20865.9 41510.8 11578.900000000001 True False 62656.579963973425 73107.3316086253 32797.8322465632 17991.62012071871 32534.307612319833 22424.028865440072 20614.26620890997 21835.405888713005 36835.41657589726 13580.297437085566 4.613785541461601 5.383338026822679 2.415104116718217 1.3248325527529718 2.395699193117374 1.651217800591298 1.5179539553099763 1.607873906287508 2.712416038496018 1.0 13.729227457534824 -5.349382164270061 4.231216624803373 1.791131646040654 5.003558041223688 0.8632438027297209 0.5089688311441323 0.06608670526816955 2.1097401191083787 0.1286541150774318 0.2904868405449816 4.473195050925427e-06 5.349382164270061 3.2124263951830345 SADTLWDIQK ddPTM_PC-9_AZD4547_30min_R2 2 SADTLWDIQK 10 0 A0A5F9ZHM4;P07195 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain 0 ; 160.36 0.00077965 12973200.0 44607.0 52280.0 55793.0 86275.0 83734.0 67139.0 49732.0 60874.0 44421.0 52442.0 False True 58791.098116761226 69178.48760887874 55053.14836550142 66385.63168546262 72108.97945404936 62940.78771646692 54158.05165635014 51467.32204535909 46769.00337273113 50606.021542102484 1.161741158961667 1.3670011097656551 1.0878774242250813 1.3118128962228741 1.4249090771551198 1.2437410766246924 1.0701898708099882 1.0170197236813021 0.924178624352458 1.0 15.627021439015818 -7.395775007891148 2.4966480766278156 0.9798906033563168 1.2738352420538015 0.6702491182035915 0.09223730230553759 0.18221791223308767 2.212698379260526 0.047685813528097955 0.02860991067983649 4.019990179205697e-08 7.395775007891148 0.29394463869748466 SADTLWDIQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SADTLWDIQK 10 0 A0A5F9ZHM4;P07195 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain 0 156.83 0.0016024999999999998 6607800.0 40598.0 42924.0 40558.0 50048.0 54609.0 55843.0 54739.0 41414.0 36961.0 43663.0 False True 47470.43955294982 47185.211045166616 41525.056537071534 47243.97281780527 43908.75846398657 52914.4947740169 49553.72564395915 40326.92638176014 37501.48470165781 51578.7562638822 0.9203486666116218 0.9148187056656086 0.8050806096336464 0.9159579687439586 0.8512954100588401 1.0258970670657688 0.9607390568015486 0.7818514695360906 0.7270722952255068 1.0 15.654489364899089 -8.335727623358553 0.004087455681114331 0.9982388422618561 0.7791782049948922 0.0013533446656749382 0.0919881148864702 597196.0546088078 1949.5775317929074 52429.223130620754 52041.841309297546 4.616069900324243e-09 8.335727623358553 -0.2190606372669639 SADTLWDIQK ddPTM_PC-9_Lapatinib_30min_R1 2 SADTLWDIQK 10 0 A0A5F9ZHM4;P07195 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain 0 ; 175.73 0.0027193 47829000.0 475960.0 420070.0 480240.0 419340.0 440240.0 429860.0 435870.0 382160.0 426210.0 428280.0 False True 469172.72311962507 419097.3537240236 440756.52098000824 450179.6624772326 414345.9487451419 411475.88985260174 458437.21587171097 399916.5487436715 378205.7416097293 502307.62735277275 0.934034638478868 0.8343439973880583 0.8774633252193542 0.8962230274099929 0.8248848438332492 0.8191710964476765 0.9126622629398151 0.7961586226577612 0.7529364895431179 1.0 18.938211656395538 -6.259218300880285 24.57306274547428 0.8422715967591513 0.8812858772454153 0.0483876562466633 0.06782322487981819 463.5385550085817 5128389.3113595005 0.019754970762824814 0.024273601098154553 5.505308989904894e-07 6.259218300880285 0.039014280486263986 SADTLWGIQK ddPTM_PC-9_AZD4547_30min_R2 1 SADTLWGIQK 10 0 P00338-3;P00338;P00338-4 P00338-3 LDHA L-lactate dehydrogenase A chain 0 183.47 0.0070924 6176400.0 25428.0 34102.0 31231.0 44854.0 41979.0 37151.0 31333.0 39605.0 30461.0 35454.0 False True 33513.57506474331 45124.80459904322 30816.856534027113 34513.603287391954 36150.94046028532 34827.942097059284 34121.57629993606 33484.95728236104 32071.106272635974 34212.76625135774 0.9795634418603412 1.3189463917508406 0.900741445681965 1.0087931222463566 1.056650613829002 1.0179808858828283 0.9973346220895524 0.9787269768352095 0.9374017300154216 1.0 15.06224713655711 -5.280598253999833 24.990100213926514 0.9911562320625678 1.1492549752582653 0.3607091568772409 0.0861660089383998 716.6078443967662 934714.9576033396 0.021064189345318573 0.04396162742435984 5.240850195461124e-06 5.280598253999833 0.1580987431956975 SADTLWGIQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SADTLWGIQK 10 0 P00338-3;P00338;P00338-4 P00338-3 LDHA L-lactate dehydrogenase A chain 0 ; 183.47 0.00051203 14470100.0 77673.0 74481.0 70965.0 90258.0 102125.0 79479.0 84606.0 80153.0 70349.0 72762.0 False True 90821.50478832162 81874.98145221922 72657.07473626136 85201.13688038405 82114.33936044667 75310.98132521693 76591.50718560442 78049.06867912356 71377.7210377677 85953.17461632512 1.0566393294224161 0.952553315426568 0.8453099616225411 0.9912506112857611 0.955338063160388 0.8761861520692812 0.8910840993074544 0.908041721873757 0.8304256515990381 1.0 16.391263305100935 -6.750276701471804 24.469155851649003 0.8947711697237926 0.9551326707267207 0.1754834852317072 0.06278884394513677 300.2061618135945 658065.5605318453 0.020704786561490607 0.020513635145374513 1.7771467780727634e-07 6.750276701471804 0.06036150100292814 SADTLWGIQK ddPTM_PC-9_Lapatinib_30min_R1 2 SADTLWGIQK 10 0 P00338-3;P00338;P00338-4 P00338-3 LDHA L-lactate dehydrogenase A chain 0 ; 183.47 0.0070924 55597000.0 131291.0 129916.0 126074.0 115424.0 129797.0 120044.0 121258.0 111524.0 130354.0 118452.0 False True 129418.76626417944 129615.18748401511 115708.68237971349 123912.66600317624 122162.5956507204 114909.99795623161 127536.14592004938 116705.81217837856 115672.15983152599 138926.27037263103 0.9315643896366731 0.9329782418858469 0.8328783466896302 0.8919311349164922 0.8793340188508139 0.8271293661596006 0.9180131704246374 0.8400557494658694 0.8326154550990797 1.0 17.083959907108984 -5.233370284725707 23.647178780208044 0.8722262573212272 0.9322713751278651 0.15267799065562837 0.05004829519219744 580.9528042491381 489426.81556640094 0.011742777266066547 0.0310467766784781 5.84291697544287e-06 5.233370284725707 0.060045117806637904 SADVS(ph)PTTEGVK ddPTM_PC-9_AZD4547_30min_R2 1 SADVSPTTEGVK 12 0 A0A0J9YX34;Q9C040;Q9C040-2 A0A0J9YX34 TRIM2 Tripartite motif-containing protein 2 1 S(0.009)ADVS(0.943)PT(0.037)T(0.011)EGVK 145.81 0.00011485 30433000.0 38662.0 41173.0 41613.0 57999.0 56807.0 53087.0 43273.0 51147.0 37363.0 41926.0 True False 50955.711780443016 54481.367068101754 41061.184430548834 44628.22662561746 48920.32861019626 49767.46149784897 47124.21316909115 43243.406391135475 39337.93190192371 40458.18350128119 1.2594661294872371 1.3466093223482583 1.014904300615685 1.1030704486325793 1.2091578112657255 1.2300962917989875 1.1647634443992985 1.068842015355585 0.9723108774934986 1.0 15.304143926521181 -1.5228787505026573 0.10097872000441493 0.8903089701525756 1.9820298929074267 0.42541978231824984 0.08974476302238206 140.57319442291697 1.0084159351889574 1.2260906176146635 21.266448213743733 0.029999999639254933 1.5228787505026573 1.0917209227548512 SADVS(ph)PTTEGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SADVSPTTEGVK 12 0 A0A0J9YX34;Q9C040;Q9C040-2 A0A0J9YX34 TRIM2 Tripartite motif-containing protein 2 1 SADVS(0.447)PT(0.447)T(0.105)EGVK;SADVS(0.98)PT(0.017)T(0.003)EGVK 131.32 0.00011995 8229600.0 50259.0 53218.0 44621.0 63441.0 66605.0 58054.0 64459.0 50689.0 46836.0 43531.0 True False 58766.85603950213 58501.131334490696 45684.933866084844 59886.606448497114 53554.22837799313 55009.54604177383 58352.976877253226 49358.46745943493 47520.88789499327 51422.82570879359 1.1428165455608688 1.1376490989775903 0.8884174145698972 1.164591902973861 1.0414485715209356 1.0697495768375656 1.1347679959811026 0.9598552156381082 0.9241205095204819 1.0 15.65012126867969 -7.781158050026817 23.562446575444625 0.9564906657005652 1.0784684399217717 0.3437749687167828 0.07664725461669694 146.4590056960247 175003.57874187062 0.04115844722407363 0.019827060196878615 1.655167499276675e-08 7.781158050026817 0.12197777422120648 SADVS(ph)PTTEGVK ddPTM_PC-9_Lapatinib_30min_R1 2 SADVSPTTEGVK 12 0 A0A0J9YX34;Q9C040;Q9C040-2 A0A0J9YX34 TRIM2 Tripartite motif-containing protein 2 1 SADVS(1)PTTEGVK;S(0.053)ADVS(0.917)PT(0.024)T(0.006)EGVK 157.5 0.00042521 58599000.0 103623.0 86835.0 87260.0 84181.0 93925.0 94886.0 82723.0 86184.0 90013.0 69369.0 True False 102145.31701786903 86633.93889262638 80085.81963334062 90371.95155958385 88400.51616365489 90827.94697006942 87005.99217325234 90188.4232701606 79874.78806108865 81359.33922161747 1.2554836112868608 1.0648309059718546 0.9843469772436589 1.1107753876099782 1.0865441756214087 1.1163800964835775 1.0694038693732966 1.108519613519639 0.9817531561252606 1.0 16.31202034161646 SADVS(ph)PTTEGVKR ddPTM_PC-9_AZD4547_30min_R2 1 SADVSPTTEGVKR 13 1 A0A0J9YX34;Q9C040;Q9C040-2 A0A0J9YX34 TRIM2 Tripartite motif-containing protein 2 1 S(0.057)ADVS(0.65)PT(0.119)T(0.174)EGVKR 60.549 0.026119999999999997 8617000.0 58364.0 51218.0 69988.0 80238.0 69786.0 81832.0 52969.0 75942.0 63614.0 64516.0 True False 76922.53795338514 67773.21687742065 69059.91339065315 61740.368764742314 60097.41849404399 76715.03210375391 57683.13838545028 64206.908873553 66976.50616944511 62257.31447714204 1.2355582408172694 1.0885984634352288 1.1092658584881412 0.9916966268663978 0.9653069522635599 1.2322252051511162 0.9265278926643843 1.0313151059081862 1.075801401521033 1.0 15.925955725806096 -3.640491077887368 0.9556515097070227 1.0365001762177795 2.614630276771373 0.35509144216516175 0.08011714753251964 16.787771523129827 2.2535366353464257 0.025624505695857946 45.21363614194853 0.00022882787213152257 3.640491077887368 1.5781301005535935 SAEALGPGALVS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 SAEALGPGALVSPR 14 0 Q9P227;Q9P227-2 Q9P227 ARHGAP23 Rho GTPase-activating protein 23 1 SAEALGPGALVS(1)PR 158.65 1.3094e-12 0.0 36081.0 43933.0 69927.0 79753.0 65120.0 59667.0 61003.0 71188.0 69986.0 65894.0 True False 47554.00746857807 58133.48309336007 68999.7222905099 61367.17802156705 56079.21205302128 55936.01305766301 66432.14882152987 60187.53033750086 73685.31708074918 63587.07111657265 0.747856547463846 0.9142343258236465 1.0851218821513946 0.9650889236439917 0.881927899308534 0.879675884978518 1.0447430217337956 0.9465372328151505 1.158809735797764 1.0 15.956445837950026 -7.271150407162485 24.53982995429449 1.0330672766038724 0.921276791735651 0.2994712140411071 0.09311082155709148 829.379485409653 2095837.4588324502 0.04019891974791621 0.027497293105277595 5.3561112970877093e-08 7.271150407162485 -0.11179048486822141 SAEALGPGALVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 SAEALGPGALVSPR 14 0 Q9P227;Q9P227-2 Q9P227 ARHGAP23 Rho GTPase-activating protein 23 1 SAEALGPGALVS(1)PR 133.87 0.00014576 0.0 49308.0 45016.0 54612.0 44740.0 48994.0 46971.0 43552.0 50086.0 46630.0 46240.0 True False 48604.85887802022 44911.76821777478 50122.012168416295 48030.328848264835 46112.269245910116 44962.15982474893 45806.909458427355 52413.17840793249 41378.038364331434 54232.522389072954 0.8962308359792126 0.828133493322889 0.9242058078883518 0.885637007692311 0.8502696761012365 0.8290626702218102 0.8446391102704226 0.966452897615785 0.7629746237410578 1.0 15.726870652126035 -10.74077722802581 4.736208374026884 1.000026205015366 0.8673887950471536 0.3602786257572195 0.0537861804506637 1.400449871378598e-05 2.3126059903313187e-06 0.04900457290691483 0.011883007432949306 1.8164471730122575e-11 10.74077722802581 -0.1326374099682125 SAEPPRS(ph)PLLK ddPTM_PC-9_AZD4547_30min_R2 1 SAEPPRSPLLK 11 1 Q6P0Q8;Q6P0Q8-2;A0A669KBJ4;H7C1I9;O15021-2;O15021-3;O15021-6;O15021;Q9Y2H9 Q6P0Q8;H7C1I9;Q9Y2H9 MAST2;MAST4;MAST1 Microtubule-associated serine/threonine-protein kinase 2;Microtubule-associated serine/threonine-protein kinase 4;Microtubule-associated serine/threonine-protein kinase 1 1 S(0.001)AEPPRS(0.999)PLLK 64.22399999999999 0.022516 11492000.0 27855.0 44506.0 45318.0 51393.0 44371.0 48341.0 58117.0 64035.0 64141.0 59771.0 True False 36712.31058000727 58891.694137734354 44717.05370974484 39545.13786393486 38210.85254921081 45318.22962811076 63289.300412452794 54139.86212791288 67531.36231355321 57678.43548287651 0.6364997641259942 1.021034874554079 0.7752820154600132 0.6856139132913022 0.6624807387598921 0.7857049042456218 1.0972783828583912 0.9386499768008763 1.1708251402485044 1.0 15.815744411817034 -7.2360073521132655 9.092403825559234 1.0465790569587226 0.7654291816319282 0.6066711385503294 0.11456594206285842 0.26445029447244306 90.66072064371183 0.04487001433830865 0.03422720803942088 5.8075458592129297e-08 7.2360073521132655 -0.28114987532679436 SAEPPRS(ph)PLLK ddPTM_PC-9_Lapatinib_30min_R1 1 SAEPPRSPLLK 11 1 Q6P0Q8;Q6P0Q8-2;A0A669KBJ4;H7C1I9;O15021-2;O15021-3;O15021-6;O15021;Q9Y2H9 Q6P0Q8;H7C1I9;Q9Y2H9 MAST2;MAST4;MAST1 Microtubule-associated serine/threonine-protein kinase 2;Microtubule-associated serine/threonine-protein kinase 4;Microtubule-associated serine/threonine-protein kinase 1 1 SAEPPRS(1)PLLK 60.06399999999999 0.030747000000000003 3142300.0 26035.0 24150.0 23711.0 26717.0 30263.0 29433.0 36208.0 33594.0 37713.0 32321.0 True False 25663.73612576572 24094.082158771565 21761.573107106855 28681.857305299323 28482.989839347225 28174.219201674114 38082.673072895355 35154.89988092648 33465.364804504214 37907.64178497462 0.6770069283480991 0.6355996053629928 0.5740682374953867 0.7566246792135695 0.7513785742967787 0.743233234119076 1.0046173087978822 0.9273829292873809 0.8828131539896743 1.0 15.210201089528216 -6.8386902204801405 0.9856646725080345 0.9586938368441559 0.6387650771780063 0.8161077429738572 0.061458056495016504 0.22463117331327215 0.4647678679805781 0.037763110026021826 0.0318552667591609 1.4498056220336614e-07 6.8386902204801405 -0.31992875966614953 SAEPRPELGPGQETGT(ph)NSR ddPTM_PC-9_AZD4547_30min_R2 1 SAEPRPELGPGQETGTNSR 19 1 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;Q9Y4B5-4 Q9Y4B5;Q9Y4B5-4 MTCL1 Microtubule cross-linking factor 1 1 SAEPRPELGPGQET(0.287)GT(0.547)NS(0.167)R 71.202 0.004672 15197000.0 27874.0 22094.0 27489.0 38973.0 36691.0 32508.0 31538.0 46510.0 31593.0 29033.0 True False 36737.35218478274 29235.45342828165 27124.47789900647 29988.376976847692 31597.087982761128 30475.26962103855 34344.82090279843 39322.94819347591 33262.94148161217 28016.56350695745 1.3112726039958338 1.0435060467362998 0.9681586355967803 1.0703802759178718 1.127800273395933 1.0877590184631503 1.2258755751493027 1.4035607252013869 1.1872598676619233 1.0 14.773992386156188 -7.279725266696568 6.3765134212148835 1.2385814103110568 1.0923950823604618 0.11539540023885242 0.12424548375692702 0.2584752470356552 45.51327485023117 0.05070797669754993 0.035265899475452576 5.2513955680501835e-08 7.279725266696568 -0.14618632795059505 SAEPRPELGPGQETGTNS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 SAEPRPELGPGQETGTNSR 19 1 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;Q9Y4B5-4 Q9Y4B5;Q9Y4B5-4 MTCL1 Microtubule cross-linking factor 1 1 SAEPRPELGPGQET(0.02)GT(0.079)NS(0.901)R 84.37100000000001 0.00064088 14684000.0 32200.0 19745.0 49122.0 55465.0 50821.0 43780.0 44350.0 48490.0 40664.0 50102.0 True False 42438.93019839288 26127.185115480275 48470.61018425538 42678.40117570771 43765.38138431503 41042.42967912723 48297.064082665696 40996.984689349505 42813.416022798636 48347.944229861954 0.8777814832544754 0.5403990910402122 1.0025371493317323 0.8827345579121342 0.9052170072886673 0.8488971006501969 0.9989476254263396 0.8479571436261368 0.8855271243643709 1.0 15.56116692669858 -5.275826196238132 24.999490598151382 0.9142573773220172 0.7090902645001365 0.44415711288318993 0.09476262790485492 589.357281386073 1024106.355892346 0.022805997649714964 0.047824455849611196 5.298754565374038e-06 5.275826196238132 -0.20516711282188071 SAEPRPELGPGQETGTNS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SAEPRPELGPGQETGTNSR 19 1 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;Q9Y4B5-4 Q9Y4B5;Q9Y4B5-4 MTCL1 Microtubule cross-linking factor 1 1 SAEPRPELGPGQET(0.002)GT(0.005)NS(0.992)R;SAEPRPELGPGQET(0.399)GT(0.023)NS(0.578)R 77.631 0.0015819 20021900.0 35305.0 39473.0 47552.0 38933.0 49902.0 31815.0 41823.0 42084.0 30291.0 26577.0 True False 41281.439194465085 43391.61857203108 48685.82002196422 36751.71023248905 40124.061324504364 30146.565392893415 37861.22266770136 40979.33959168382 30733.94857005807 31395.199716583767 1.3148965309068936 1.382109971070211 1.550740892285106 1.1706155897799826 1.2780317273570259 0.9602284955992558 1.2059557833518757 1.305274053410065 0.9789378264035566 1.0 14.938256369415065 -5.862451316522242 7.0758135072256785 1.1413231066663658 1.4115283657424282 0.521275532808317 0.12600527323069458 0.18245591540356157 11.135973816508562 0.03519062814777642 0.052576114208937354 1.3726148195541646e-06 5.862451316522242 0.2702052590760624 SAEPRPELGPGQETGTNS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 2 SAEPRPELGPGQETGTNSR 19 1 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;Q9Y4B5-4 Q9Y4B5;Q9Y4B5-4 MTCL1 Microtubule cross-linking factor 1 1 SAEPRPELGPGQET(0.002)GT(0.013)NS(0.985)R;SAEPRPELGPGQET(0.003)GT(0.007)NS(0.99)R 116.27 3.244e-05 36984000.0 88455.0 82677.0 82641.0 84005.0 93024.0 86037.0 80791.0 70348.0 85668.0 74042.0 True False 87193.6154793395 82485.56648615978 75846.57598348531 90183.007932465 87552.51121222066 82357.39807204284 84973.96266660099 73616.62489800001 76019.16771596712 86840.06104523667 1.0040713287145049 0.9498561550203362 0.873405373862823 1.0384954460762865 1.00820416474158 0.9483802415700892 0.9785110885900506 0.8477265447758229 0.8753928405965453 1.0 16.406073119662217 -7.740388686679082 24.994289146528647 0.8961697585718099 0.9700428147972401 0.20733760185195282 0.05580897535479198 309.90974249342827 367968.35687746655 0.026402755646409534 0.01522393272870177 1.818072983747909e-08 7.740388686679082 0.07387305622543017 SAEPSANTTLVS(ph)ETEEEGSVPAFGAAAK ddPTM_PC-9_AZD4547_30min_R2 2 SAEPSANTTLVSETEEEGSVPAFGAAAK 28 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 1 S(0.002)AEPS(0.005)ANT(0.004)T(0.003)LVS(0.427)ET(0.427)EEEGS(0.132)VPAFGAAAK;SAEPS(0.001)ANT(0.001)T(0.004)LVS(0.526)ET(0.453)EEEGS(0.015)VPAFGAAAK 68.543 0.00011545 4642900.0 48544.0 66632.0 62245.0 54277.0 51934.0 79759.0 69062.0 85995.0 75447.0 61705.0 True False 63979.98222207404 88169.49094022193 61419.59062983947 41764.276221290704 44723.86054609347 74771.65712145978 75208.38420917824 72706.44871851115 79434.97439189674 59544.7267315403 1.0744861171423334 1.4807271068307608 1.031486648796829 0.7013933645138142 0.751096914891099 1.2557225673160057 1.2630570050016041 1.2210392541779724 1.3340387764315789 1.0 15.861686128526914 SAEPSANTTLVS(ph)ETEEEGSVPAFGAAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAEPSANTTLVSETEEEGSVPAFGAAAK 28 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 1 S(0.003)AEPS(0.026)ANT(0.006)T(0.006)LVS(0.406)ET(0.406)EEEGS(0.147)VPAFGAAAK 45.14 0.018394 2326400.0 26812.0 42867.0 31017.0 27360.0 33675.0 20562.0 31964.0 16924.0 20873.0 17889.0 True False 31350.742038861314 47122.552461866515 31756.562912627538 25827.107902316817 27076.62548801017 19483.69252266775 28936.138520680164 16479.762932460235 21178.228137163595 21132.13409075392 1.483557784756742 2.2299003148235914 1.5027617549768526 1.2221722515766698 1.281301044737227 0.9219936064664939 1.3692956137989292 0.7798437612446693 1.0021812300741477 1.0 14.367150848984124 -5.693594026151614 2.0693374580724093 1.0640868010788138 1.865511571216483 0.6394129746432384 0.23554113386342834 0.18656193585256398 1.6209162172708065 0.0680477305015261 0.14195982116361897 2.0249111595878076e-06 5.693594026151614 0.8014247701376691 SAEPSANTTLVSET(ph)EEEGSVPAFGAAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAEPSANTTLVSETEEEGSVPAFGAAAK 28 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 1 SAEPS(0.001)ANT(0.002)T(0.002)LVS(0.41)ET(0.549)EEEGS(0.037)VPAFGAAAK 59.56100000000001 0.0038396999999999997 2656500.0 8738.2 14499.0 9953.2 10879.0 10635.0 7281.3 9821.5 6293.6 5414.4 6257.1 True False 10217.404672683042 15938.36489944718 10190.522035721206 10269.48490019388 8551.148093986283 6899.455810003922 8891.136418497688 6128.399668620407 5493.575356961559 7391.462698823658 1.3823251349572703 2.156320818879834 1.3786881502281023 1.3893711324320497 1.1568952509693633 0.9334357881697708 1.202892685897299 0.8291186627507076 0.7432325076653441 1.0 12.851644172650369 -6.050003081844918 0.9560301350446995 0.9164691497117701 1.7807757520905931 0.6604615923375545 0.22354147293478688 0.3434691730436711 0.6434895378460738 0.09592317866899155 0.19746814418651468 8.912446136522174e-07 6.050003081844918 0.8643066023788231 SAEPSPTVMST(ph)SLGSNLSELDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SAEPSPTVMSTSLGSNLSELDR 22 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 SAEPSPTVMS(0.007)T(0.496)S(0.496)LGSNLSELDR;SAEPSPTVMS(0.007)T(0.814)S(0.177)LGS(0.001)NLSELDR 144.73 8.543799999999999e-07 7180400.0 13328.400000000001 12610.0 16515.5 19129.0 25642.9 31541.0 29265.4 29265.2 29837.0 26955.3 True False 15584.634872100505 13861.83746341328 16909.29215538254 18057.264147054764 20618.357824097882 29886.93443524287 26493.169448852244 28497.019509042504 30273.309678941707 31842.082511962606 0.4894351638667347 0.43533074377926095 0.5310360008341152 0.5670880395549165 0.6475191381201862 0.9385986115705461 0.83201748625892 0.8949483595596045 0.9507327188028127 1.0 14.958647072573982 -6.506720744131844 1.2326631320664998 0.9298929622863911 0.471816789612933 0.933031655726939 0.05305769663822349 0.10506488933025553 0.3331883793431449 0.02322452933801553 0.026604844069957338 3.1137178464966885e-07 6.506720744131844 -0.45807617267345807 SAEPSPTVMSTS(ph)LGSNLSELDR ddPTM_PC-9_AZD4547_30min_R2 4 SAEPSPTVMSTSLGSNLSELDR 22 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 SAEPSPTVMS(0.001)T(0.248)S(0.747)LGS(0.003)NLSELDR;SAEPSPTVMS(0.002)T(0.236)S(0.705)LGS(0.054)NLS(0.004)ELDR;SAEPSPTVMS(0.148)T(0.148)S(0.703)LGSNLSELDR;SAEPSPTVMS(0.006)T(0.004)S(0.99)LGSNLSELDR 177.02 6.0947e-13 40248900.0 97398.8 86166.9 128222.8 173374.0 176312.2 159303.2 124566.0 175013.9 149716.0 167380.9 True False 128369.5923791067 114018.66533943164 126522.48189271077 133405.3029015982 151834.2944001032 149341.9457208758 135652.13268368255 147969.52317433155 157629.6821087283 161520.94563778111 0.7947550819011548 0.7059063757286579 0.7833193484171633 0.8259319085511443 0.9400285133334921 0.9245980150201861 0.8398423631563507 0.9161011445918642 0.9759086135009439 1.0 17.30136173662141 -5.3884183977660705 0.2895867631753955 0.9937002985163043 0.5906954961021524 0.7390600161241321 0.0459957133807298 3.1546672676412957 0.2884224075066874 0.0625610159107986 0.4398660263464804 4.0886656932271195e-06 5.3884183977660705 -0.4030048024141518 SAEPSPTVMSTS(ph)LGSNLSELDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SAEPSPTVMSTSLGSNLSELDR 22 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 SAEPSPTVMS(0.057)T(0.057)S(0.886)LGSNLSELDR;SAEPSPTVMS(0.011)T(0.011)S(0.972)LGS(0.005)NLS(0.001)ELDR 183.21 2.9773000000000005e-15 6889700.0 14005.0 13885.900000000001 17106.1 22754.5 30693.3 39260.0 34038.0 40487.0 40091.0 31426.9 True False 16375.769888641378 15264.40038328393 17513.97429924551 21479.639136084355 24679.16819869764 37201.13648671995 30813.67422622047 39424.25914952242 40677.25503027961 37124.3481947965 0.44110592333407417 0.41116951880715985 0.47176516628244375 0.5785862966099168 0.6647704107612258 1.0020684078147457 0.8300125315207405 1.0619515511129778 1.0957028744812036 1.0 15.18007807578232 -6.5239696051676095 0.9334535662434055 1.0413663929017445 0.4098520155595065 0.9256656846602194 0.07074139277534199 0.1345657128082213 0.255411022736864 0.037502652216103605 0.04453595636146564 2.992474062628056e-07 6.5239696051676095 -0.631514377342238 down SAEPSPTVMSTS(ph)LGSNLSELDR ddPTM_PC-9_Lapatinib_30min_R1 4 SAEPSPTVMSTSLGSNLSELDR 22 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 SAEPSPTVMS(0.002)T(0.26)S(0.71)LGS(0.028)NLSELDR;SAEPSPTVMS(0.148)T(0.148)S(0.704)LGSNLSELDR;SAEPSPTVMS(0.048)T(0.048)S(0.905)LGSNLSELDR;SAEPSPTVMS(0.01)T(0.238)S(0.643)LGS(0.103)NLS(0.006)ELDR 188.56 1.3635e-15 44993100.0 66262.0 59892.0 73608.0 73864.0 124419.0 128369.0 104070.0 104092.0 158075.0 127133.0 True False 65317.09172903739 59753.323753753524 67556.23437509674 79296.20496308088 117100.91903716544 122878.95711275456 109458.23538157923 108928.49432652837 140270.92889645483 149107.769655926 0.43805290549084064 0.4007391693379725 0.45306984693679136 0.5318046480479255 0.7853441796318323 0.8240949307759361 0.7340880735736296 0.7305353341270315 0.9407352093062444 1.0 17.18599590946947 -5.832082316089919 0.32490702818555883 0.9786970746767547 0.1431599606000632 0.8674592186605556 0.07439328986172891 1.3679116645832958 0.19545076632460148 0.09442037950986372 0.42857668342612265 1.4720334670581609e-06 5.832082316089919 -0.8355371140766915 down SAES(ph)PSWTPAEHVAK ddPTM_PC-9_AZD4547_30min_R2 4 SAESPSWTPAEHVAK 15 0 Q13415 Q13415 ORC1 Origin recognition complex subunit 1 1 S(0.005)AES(0.924)PS(0.071)WTPAEHVAK;S(0.001)AES(0.774)PS(0.196)WT(0.03)PAEHVAK;S(0.128)AES(0.649)PS(0.215)WT(0.008)PAEHVAK;S(0.077)AES(0.873)PS(0.05)WTPAEHVAK 155.06 0.00018618 62527000.0 274107.0 199318.1 304993.0 371381.0 360708.0 328463.0 283669.0 337855.0 285597.0 356975.0 True False 361267.3242202144 263743.77794711594 300948.5935411141 285764.84822925244 310629.92047329864 307924.15668559115 308914.99146033154 285647.2728855478 300693.0743621686 344477.41390473425 1.0487402356083741 0.765634457590461 0.8736381004774435 0.829560478261954 0.9017424885777964 0.8938877971568494 0.8967641389277338 0.8292191631598348 0.8728963416026043 1.0 18.39404986835087 SAES(ph)PSWTPAEHVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SAESPSWTPAEHVAK 15 0 Q13415 Q13415 ORC1 Origin recognition complex subunit 1 1 SAES(0.98)PS(0.02)WT(0.001)PAEHVAK;S(0.005)AES(0.857)PS(0.129)WT(0.009)PAEHVAK;SAES(0.894)PS(0.099)WT(0.006)PAEHVAK;SAES(0.983)PS(0.017)WTPAEHVAK 151.9 5.4611e-10 5020200.0 58938.0 62993.0 75080.0 76278.0 89436.0 85271.0 75682.0 90173.0 82069.0 60531.0 True False 68915.03932143847 69246.52873376623 76870.19194248575 72004.39095661264 71911.65782169782 80799.23864898356 68512.85306976973 87806.05429619086 83269.10386570597 71504.79113686761 0.9637821218095429 0.9684180267196525 1.0750355426582283 1.0069869418790238 1.0056900618596512 1.1299835628402215 0.9581575161673991 1.2279744182193462 1.1645248177331256 1.0 16.1257522916198 -6.934449392538379 0.9082460990917617 1.1230031014889026 0.9971549310518033 0.23126964310294618 0.07874015425466792 0.7840915833727138 1.3615164598018934 0.05219100664460209 0.04052641796793274 1.1629220560740434e-07 6.934449392538379 -0.12584817043709928 SAES(ph)PSWTPAEHVAK ddPTM_PC-9_Lapatinib_30min_R1 4 SAESPSWTPAEHVAK 15 0 Q13415 Q13415 ORC1 Origin recognition complex subunit 1 1 S(0.01)AES(0.976)PS(0.013)WT(0.001)PAEHVAK;S(0.159)AES(0.74)PS(0.1)WTPAEHVAK;S(0.182)AES(0.527)PS(0.251)WT(0.04)PAEHVAK;S(0.135)AES(0.603)PS(0.262)WTPAEHVAK 172.09 9.719e-06 74717700.0 454365.0 393091.0 516869.0 473026.0 471444.0 426935.0 373222.0 367858.0 498453.0 372694.0 True False 447885.67177966394 392180.8219409396 474374.0259920374 507813.91000847804 443714.5908145655 408675.9852840939 392545.6089707291 384950.0256116528 442311.974197214 437113.6613164613 1.0246434998868725 0.8972055935287018 1.0852418214597972 1.1617433975389555 1.0151011740933105 0.9349421476631015 0.8980401293990539 0.8806634513602103 1.0118923596784801 1.0 18.737648942483794 -6.700026612067251 4.693991308200061 0.9344418574934521 1.0405547818887169 0.2856018126704749 0.07222588887107403 0.2703787497017056 11.843332538209665 0.02642257621545181 0.02588352438556605 1.995140055925021e-07 6.700026612067251 0.10611292439526476 SAES(ph)PTSPVTSETGSTFK ddPTM_PC-9_AZD4547_30min_R2 2 SAESPTSPVTSETGSTFK 18 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 SAES(0.982)PT(0.018)SPVTSETGSTFK;S(0.001)AES(0.965)PT(0.034)SPVTSETGSTFK 216.29 1.6374000000000003e-27 10064000.0 26442.0 30029.0 37416.0 36363.0 40264.0 41478.0 37866.0 52231.0 38181.0 39191.0 True False 34850.005972233084 39735.28700089933 36919.83939281991 27980.07215274966 34674.038607230505 38884.37410303425 41236.00064383808 44159.89909897744 40199.16971194363 37818.93501881199 0.9214962281433335 1.050671759559969 0.9762263102981389 0.7398429421355134 0.9168433376027869 1.028172107006511 1.09035330115262 1.1676663839690702 1.0629376446467267 1.0 15.206821117117624 -6.933843090451159 3.259373013946011 1.0920015842558997 0.9215143214788986 0.4553462505070268 0.0824169552048108 0.23707822664229938 5.1083133156354235 0.03410397148758056 0.02897211894816148 1.1645467013264713e-07 6.933843090451159 -0.1704872627770011 SAES(ph)PTSPVTSETGSTFK ddPTM_PC-9_Lapatinib_30min_R1 2 SAESPTSPVTSETGSTFK 18 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 S(0.036)AES(0.832)PT(0.13)S(0.001)PVTSETGSTFK;S(0.001)AES(0.978)PT(0.022)SPVTSETGSTFK 214.28 2.1424999999999998e-27 9757400.0 28028.0 51581.0 48863.0 44472.0 55617.0 44714.0 40615.0 43564.0 50147.0 48781.0 True False 27628.31558029431 51461.56736362722 44845.672756634536 47742.61923424303 52345.717407229116 42801.686453424925 42717.84596927873 45588.142478200934 44498.91678867958 57212.730853403285 0.4829050312435986 0.899477556760709 0.7838408005998354 0.8344754484202893 0.914931285859349 0.7481147257783601 0.7466493092024407 0.7968181521523917 0.7777799822682746 1.0 15.804048587662486 SAESPT(ph)SPVTSETGSTFK ddPTM_PC-9_AZD4547_30min_R2 1 SAESPTSPVTSETGSTFK 18 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 SAESPT(0.736)S(0.258)PVT(0.001)S(0.005)ETGSTFK 134.56 0.00013746 17273000.0 70625.0 70948.0 71081.0 69761.0 56438.0 67570.0 53140.0 74385.0 56886.0 52332.0 True False 93082.28090874215 93880.55353624167 70138.4194964997 53678.679246705935 48602.55789079261 63344.837218333196 57869.35705417933 62890.50744725236 59892.87782492925 50499.8726086211 1.8432181330463708 1.8590255516845566 1.388883097588765 1.0629468248904486 0.9624293167522844 1.2543563764855767 1.145930753185705 1.2453597246602952 1.1860005724985654 1.0 15.623992128064527 -5.406906724575816 2.8594611719075664 1.133942865870985 1.8635314981676079 0.9048962654435033 0.09339538112348843 0.07652790942077561 1.1879838921817105 0.027209855659165456 0.0673818663492636 3.918260223490465e-06 5.406906724575816 0.729588632296623 SAESPT(ph)SPVTSETGSTFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAESPTSPVTSETGSTFK 18 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 SAESPT(0.9)S(0.099)PVTS(0.001)ETGSTFK 183.76 4.0287999999999996e-10 9216400.0 58483.0 63990.0 48661.0 48971.0 63069.0 55420.0 86655.0 78496.0 61345.0 49425.0 True False 68383.01680809805 70342.5043048227 49821.26278787019 46227.31363612413 50711.082194604714 52513.67763866585 78446.4110721294 76435.56317338697 62242.054571661996 58385.361251915274 1.1712356546540135 1.2047969353365127 0.8533177104601002 0.7917620555033851 0.8685581643624957 0.8994322637156449 1.3435972543469712 1.309156294222288 1.0660558269581695 1.0 15.83331907234273 -7.249822411568828 24.820495651184682 1.2054653714721213 0.9584428676518871 0.30327549773552887 0.15743242810861455 813.831439728079 1738812.3635618908 0.06594148117739354 0.050637990357387336 5.625713205938266e-08 7.249822411568828 -0.24702250382023416 SAESPT(ph)SPVTSETGSTFK ddPTM_PC-9_Lapatinib_30min_R1 1 SAESPTSPVTSETGSTFK 18 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 SAESPT(0.499)S(0.499)PVTS(0.002)ETGSTFK 272.32 1.8925999999999996e-79 10686000.0 28810.0 46460.0 48042.0 30588.0 69956.0 77357.0 98732.0 89986.0 72659.0 75148.0 True False 28399.164116893076 46352.424724493874 44092.17220748292 32837.54355857675 65841.32561878777 74048.62143797457 103843.85986061381 94167.07807004396 64475.37828681005 88137.23167158439 0.32221529515147024 0.5259119652998812 0.5002672692486928 0.3725728949706011 0.7470319224924685 0.8401514324150027 1.1782065069567333 1.068414293075688 0.7315339620270492 1.0 16.427463962840562 -6.577631056096552 2.015623814802117 0.9947534126284895 0.4399580136484891 0.8003296839048955 0.12553015295111283 0.14153602938746435 1.1677267628017332 0.04769685421299192 0.04970089162849916 2.644654502687009e-07 6.577631056096552 -0.5547953989800004 down SAESPT(ph)SPVTSETGSTFKK ddPTM_PC-9_AZD4547_30min_R2 2 SAESPTSPVTSETGSTFKK 19 1 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 SAES(0.014)PT(0.547)S(0.438)PVT(0.001)SETGSTFKK;S(0.001)AES(0.057)PT(0.458)S(0.458)PVT(0.024)S(0.001)ETGSTFKK 98.06200000000001 0.00048597 79742000.0 67687.0 41284.0 60824.0 84899.0 66226.0 61263.0 49652.0 64151.0 48277.0 50188.0 True False 89210.05802293863 54628.24564737846 60017.4340183044 65326.84722647452 57031.663043970904 57432.214925362576 54070.93181133068 54237.936993327756 50828.8236605511 48430.93339603827 1.8420057547401338 1.1279618586051687 1.2392376072440907 1.3488661614731208 1.1775875260879483 1.1858581055152784 1.1164544645293533 1.1199027809314224 1.0495115434778917 1.0 15.563641187421036 -4.759529769724751 24.999937014013618 1.1651264280305154 1.842006607934379 0.8320041072549266 0.09287990589429469 20.355165006904866 266411.37341636454 0.02410250500197559 0.15220372746648972 1.7396834433056364e-05 4.759529769724751 0.6768801799038637 SAESPT(ph)SPVTSETGSTFKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAESPTSPVTSETGSTFKK 19 1 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 S(0.001)AES(0.044)PT(0.529)S(0.42)PVT(0.006)SETGSTFKK 100.04 0.00039754 17157000.0 22688.0 8184.3 12251.0 17042.0 15249.0 19106.0 21681.0 24622.0 22653.0 18306.0 True False 26528.630291574118 8996.783215845613 12543.110302176221 16087.191990909463 12261.067915862419 18104.047725809258 19627.218723153113 23975.698589165444 22984.257269734444 21624.73288978373 1.2267726231248461 0.41604135698231004 0.5800353866152039 0.7439255815506332 0.5669928030257877 0.837191738648584 0.9076282617310705 1.1087165197075055 1.0628689559718447 1.0 14.40039469213861 -7.291710610572921 1.9277615903456677 1.0601622994610416 0.6876882914640671 0.34840602467306014 0.2030086617858341 0.35844379546446015 2.5981787069012556 0.10377685939577135 0.06393207280930396 5.1084528516810865e-08 7.291710610572921 -0.3724740079969745 SAESPT(ph)SPVTSETGSTFKK ddPTM_PC-9_Lapatinib_30min_R1 1 SAESPTSPVTSETGSTFKK 19 1 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 SAES(0.005)PT(0.493)S(0.493)PVT(0.008)SETGSTFKK 104.18 0.00022419 23926000.0 19178.0 17787.0 18035.0 11570.0 20629.0 20848.0 20198.0 21175.0 25295.0 18243.0 True False 18904.51820318553 17745.815294330012 16552.231917113237 12420.896396388562 19415.642778174464 19956.379639061663 21243.753610426993 22158.867803138026 22446.01073184138 21396.278242730492 0.8835423613734528 0.8293879474276913 0.773603321537331 0.5805166793719666 0.9074308418461066 0.9327033146917482 0.9928714409780439 1.0356412246913376 1.0490614525200213 1.0 14.385072249647205 -6.707907958463873 2.318065333592433 1.0140869131648111 0.7716728055842976 0.6561397490301306 0.07946630281557862 0.19404296206197735 2.137071686427933 0.0319972920152083 0.030560616891201705 1.9592598622475617e-07 6.707907958463873 -0.24241410758051352 SAESPTS(ph)PVTSETGSTFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAESPTSPVTSETGSTFK 18 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 SAESPT(0.032)S(0.797)PVT(0.003)S(0.169)ETGSTFK 245.18 2.1209e-53 8168300.0 39206.0 47559.0 28888.0 28114.0 39375.0 40077.0 50318.0 47843.0 39546.0 32786.0 True False 45842.801446203055 52280.34321351876 29576.799478350087 26538.863726817784 31659.75140580255 37975.29156847368 45551.514769227375 46587.171943848676 40124.28543631827 38729.84226616681 1.1836557745614655 1.3498723504791872 0.7636695051605584 0.6852303591745148 0.8174510804413869 0.980517589188524 1.1761347866118155 1.202875333797726 1.036004359650326 1.0 15.24115800530811 -9.7550866924408 13.844766003077343 1.0000004915572895 1.0165289535897126 0.0004402982801612332 0.2035320511849159 0.0 0.0 0.22236905615196265 0.053932418022555696 1.757572738031107e-10 9.7550866924408 0.016528462032423086 SAESPTS(ph)PVTSETGSTFK ddPTM_PC-9_Lapatinib_30min_R1 1 SAESPTSPVTSETGSTFK 18 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 SAESPT(0.027)S(0.972)PVTSETGSTFK 249.89 7.767300000000001e-54 15180000.0 20585.0 26669.0 26329.0 21603.0 41062.0 41993.0 59482.0 60021.0 46861.0 46565.0 True False 20291.454125173335 26607.249569038468 24164.331252879092 23191.75668549542 38646.81389099808 40197.057280464134 62561.68691233874 62809.79477743315 41583.0207117936 54613.698206037654 0.371545139620852 0.4871900355229374 0.4424591640308965 0.42465091080265877 0.7076395695672848 0.7360251841729383 1.145531047473039 1.150074007815303 0.7614027630012522 1.0 15.736975232806635 -6.723494127495987 1.5440548143934176 1.0207544575614258 0.4337065229819208 0.819973340659559 0.1189825504698671 0.1523783754051264 0.7549406555137894 0.05179312479972668 0.0484935363987342 1.8901917900744475e-07 6.723494127495987 -0.587047934579505 down SAESPTS(ph)PVTSETGSTFKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAESPTSPVTSETGSTFKK 19 1 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 SAES(0.002)PT(0.024)S(0.974)PVTSETGSTFKK 118.44 2.5676999999999998e-05 22329000.0 16508.0 13443.0 11339.0 14193.0 20704.0 23915.0 31896.0 29274.0 29801.0 17004.0 True False 19302.478352137936 14777.532198308065 11609.364763396965 13397.812224326844 16647.199824907577 22660.8553000486 28874.579972957512 28505.588518366858 30236.78324704702 20086.69059641005 0.9609586138389431 0.7356877494269338 0.5779630401372251 0.6669994820710455 0.8287676730522653 1.1281527532513798 1.437498120179043 1.419128172535373 1.5053143324889477 1.0 14.293952270477972 -6.870705799637417 2.3631841772405817 1.3738741038489573 0.7259640704437409 0.7565466108910757 0.1577187481538109 0.13338210019941632 1.5190042298613526 0.0623678865522964 0.053788582182690954 1.3467723774970023e-07 6.870705799637417 -0.6479100334052164 SAESPTS(ph)PVTSETGSTFKK ddPTM_PC-9_Lapatinib_30min_R1 1 SAESPTSPVTSETGSTFKK 19 1 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 SAESPT(0.288)S(0.71)PVT(0.002)SETGSTFKK 127.5 1.5052000000000001e-05 15813000.0 30951.0 20830.0 24691.0 22046.0 28305.0 35700.0 39407.0 32436.0 46521.0 35985.0 True False 30509.633064281745 20781.769414791397 22661.001290016244 23667.336383300095 26640.155549771105 34173.19422076464 41447.30164006811 33943.094973439685 41281.31509215229 42204.95930300148 0.722892133250132 0.49240112437008 0.5369274527035184 0.560771453738067 0.6312091277831547 0.8096961775374667 0.9820481366302493 0.8042442294459401 0.9781152682977826 1.0 15.365124912639946 -6.828989588980005 2.320378688356264 0.9256534269938997 0.5700378020562181 0.8280947141294638 0.07614317318700611 0.11586540056688431 1.277009953310992 0.029159489738690765 0.025794487877630952 1.4825536248801016e-07 6.828989588980005 -0.3556156249376816 SAFS(ph)PYQTPVAHFPPPPEEPTATAAFGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SAFSPYQTPVAHFPPPPEEPTATAAFGAR 29 0 A0A0A0MQV9;Q9UPS6-2;Q9UPS6 A0A0A0MQV9 SETD1B Histone-lysine N-methyltransferase;Histone-lysine N-methyltransferase SETD1B 1 S(0.068)AFS(0.894)PY(0.008)QT(0.029)PVAHFPPPPEEPTATAAFGAR;S(0.145)AFS(0.565)PY(0.105)QT(0.184)PVAHFPPPPEEPTATAAFGAR 95.96799999999999 7.698799999999999e-11 9372300.0 6349.6 5913.1 7880.6 7844.5 9250.3 10923.1 7268.0 5601.9 4875.6 4474.6 True False 7424.4618696834905 6500.11348968351 8068.503391341931 7404.9980972121375 7437.770118834164 10350.273406981434 6579.5224242367485 5454.856060703673 4946.89642627101 5285.80955908589 1.404602603762261 1.2297290352639223 1.5264461008574948 1.4009203348016066 1.4071203352472703 1.9581245391616748 1.2447520764207383 1.0319811941251658 0.9358824548961823 1.0 12.367908732132731 -7.59817071002565 4.107221855740965 0.9929569674103491 1.4790886231357885 0.6060945092425096 0.17944473793129015 0.1594990163325243 5.22914050698145 0.09359257122466445 0.05195087024690616 2.5224890518129876e-08 7.59817071002565 0.48613165572543937 SAFSPYQT(ph)PVAHFPPPPEEPTATAAFGAR ddPTM_PC-9_AZD4547_30min_R2 1 SAFSPYQTPVAHFPPPPEEPTATAAFGAR 29 0 A0A0A0MQV9;Q9UPS6-2;Q9UPS6 A0A0A0MQV9 SETD1B Histone-lysine N-methyltransferase;Histone-lysine N-methyltransferase SETD1B 1 S(0.062)AFS(0.277)PY(0.243)QT(0.418)PVAHFPPPPEEPTATAAFGAR 86.73200000000001 9.7295e-08 3367900.0 3466.5 2631.9 5071.1 7937.9 5967.3 3881.0 4289.9 5034.4 4149.4 5281.9 True False 4568.774892320777 3482.6102053903537 5003.853900602125 6107.939794332464 5138.84339809573 3638.320456479966 4671.692789362513 4256.449159003121 4368.728812832006 5096.982288685237 0.8963686027442112 0.6832690419822296 0.9817287204843055 1.1983443238348004 1.00821292032021 0.7138185401500519 0.9165605302834147 0.8350920050187322 0.8571206579489442 1.0 12.315427624746583 -6.705007050313877 24.999999165664057 0.8574593447808068 0.9537284489693423 0.09573238877677248 0.13600445520807317 224.63076535776293 99512.01851020522 0.049074782662874544 0.04907475602357812 1.9723907161673502e-07 6.705007050313877 0.09626910418853551 SAFSS(ph)LQNIPESLRR ddPTM_PC-9_Lapatinib_30min_R1 1 SAFSSLQNIPESLRR 15 1 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 S(0.098)AFS(0.377)S(0.525)LQNIPESLRR 55.688 0.031833 4008600.0 59602.0 48124.0 58597.0 57819.0 63369.0 51900.0 52492.0 49341.0 54915.0 43060.0 True False 58752.064550331845 48012.571834729766 53779.38085096119 62071.202138529785 59641.760008247504 49680.357984809096 55209.778914671435 51633.56298817628 48729.894419413664 50502.86362615661 1.1633412510078494 0.9506900874005674 1.0648778502751592 1.2290630210200923 1.1809579838826731 0.983713683100506 1.0932009583329252 1.022388816808282 0.9648936895961542 1.0 15.62407757379259 -7.675204057851789 1.2117117737701328 0.9827862817634793 1.1016104996390375 0.2546777925374145 0.08032335978633301 0.774713506617945 2.088738283142715 0.0704994841656866 0.029104949427724545 2.1124962279365392e-08 7.675204057851789 0.11882421787555819 SAGEALGSSGT(ph)PPVR ddPTM_PC-9_Lapatinib_30min_R1 2 SAGEALGSSGTPPVR 15 0 W0Z7M9;A0A499FIJ6;Q969V6;E7ER32;A0A087X287;A0A087WU73;A0A494BZX7;B0QY83 W0Z7M9 mkl1;MKL1 MKL/myocardin-like protein 1 1 SAGEALGS(0.008)S(0.044)GT(0.948)PPVR;SAGEALGS(0.012)S(0.05)GT(0.938)PPVR 110.55 0.002293 4210700.0 22181.8 18936.0 23701.0 15202.199999999999 16143.9 17520.6 16090.2 13524.5 18156.8 14000.6 True False 21865.48346435607 18892.154855424367 21752.39526850573 16320.22050105256 15194.347542128593 16771.28478051343 16923.271826046748 14152.897643614651 16111.789984419753 16420.58505537315 1.3315897935805423 1.1505165493017844 1.3247028163218766 0.993887881949264 0.9253231532792854 1.0213573221634709 1.0306132070799212 0.8618997189130928 0.9811946364936398 1.0 14.003217909920265 -5.80133884017728 7.9132787983414845 0.9693460286930897 1.2569283052854825 0.8094316310864241 0.06561158666711014 0.08912530612028545 15.205034653125134 0.017984753658947108 0.027048972172821664 1.5800148175082869e-06 5.80133884017728 0.28758227659239277 SAGGRPGS(ph)GPQLGTGR ddPTM_PC-9_Lapatinib_30min_R1 2 SAGGRPGSGPQLGTGR 16 1 K7EM11;O14908-2;O14908;K7ESN1 K7EM11 GIPC1 PDZ domain-containing protein GIPC1 1 SAGGRPGS(0.988)GPQLGT(0.012)GR;SAGGRPGS(0.999)GPQLGT(0.001)GR 80.733 0.0036878 121115000.0 49482.0 42069.0 41435.0 48667.0 58989.0 48947.0 55255.0 50370.0 59393.0 49311.0 True False 48776.37760611257 41971.59181521166 38028.37424372539 52246.13352835277 55519.38299683618 46853.65091102988 58115.83353520859 52710.37408472551 52703.5349039832 57834.340647222656 0.8433808885907118 0.7257209357884714 0.6575396869429271 0.9033756232658244 0.9599726110044683 0.810135472916123 1.0048672274091095 0.911402697685234 0.9112844430174056 1.0 15.819638764486285 -5.857266798064885 6.87312517994341 0.9261380495869498 0.7413270906988301 0.6220489862351861 0.06675028734647682 0.13803404757061727 8.4235508453622 0.018479748644390434 0.027644005067595703 1.3890990104470428e-06 5.857266798064885 -0.18481095888811971 SAGGRPGSGPQLGT(ph)GR ddPTM_PC-9_AZD4547_30min_R2 1 SAGGRPGSGPQLGTGR 16 1 K7EM11;O14908-2;O14908;K7ESN1 K7EM11 GIPC1 PDZ domain-containing protein GIPC1 1 SAGGRPGS(0.003)GPQLGT(0.997)GR 95.751 0.024928 19764000.0 7483.6 8372.8 13361.0 18100.0 15338.0 14414.0 7654.3 16840.0 9919.4 11966.0 True False 9863.2291314501 11079.143860972052 13183.82441007769 13927.324642212387 13208.583453151736 13512.690301391965 8335.517871656097 14237.764944702954 10443.719233143538 11547.073982166943 0.8541756246372598 0.9594763035278415 1.1417459029394381 1.2061345292947332 1.1438900862288397 1.170226355374589 0.7218727345584945 1.233019288409467 0.9044472434551469 1.0 13.495239699916722 SAGQGEVLVYVEDPAGHQEEAK ddPTM_PC-9_Lapatinib_30min_R1 1 SAGQGEVLVYVEDPAGHQEEAK 22 0 Q60FE5;P21333-2;P21333;A0A087WWY3;F8WE98 Q60FE5 FLNA Filamin-A 0 106.35 2.9727e-05 13697000.0 47263.0 39703.0 53801.0 41248.0 52639.0 43669.0 42561.0 39483.0 43942.0 46112.0 False True 46589.02095302729 39611.070142845034 49377.68945786576 44281.51551929433 49542.87751225581 41801.378667410965 44764.6003274276 41317.52431977795 38992.789230226284 54082.39775962224 0.8614451814821442 0.7324207465597715 0.9130085111487235 0.8187787034907461 0.9160628885660165 0.7729202180199887 0.8277110886686448 0.7639736038224528 0.7209885442493859 1.0 15.722871494912741 -9.92184549502266 11.466052081890684 1.0000023291503541 0.8154942417147059 0.42409285423810583 0.0649569622560894 0.0 0.0 0.062458866947689075 0.01514850033421893 1.1971663604871905e-10 9.92184549502266 -0.18450808743564828 SAGS(ph)IPGER ddPTM_PC-9_AZD4547_30min_R2 1 SAGSIPGER 9 0 Q04206;Q04206-4;Q04206-3;Q04206-2;A0A087X0W8;E9PKH5;Q2TAM5;E9PQS6;A0A087WVP0;E9PKV4;E9PMD5;E9PI38;E9PNV4;E9PRX2;E9PJR1;E9PM47;E9PN69;E9PNK5;E9PJZ9 Q04206 RELA Transcription factor p65 1 S(0.009)AGS(0.991)IPGER 82.26100000000001 0.016033000000000002 4745500.0 45547.0 48253.0 65219.0 80496.0 71958.0 63981.0 45204.0 63997.0 50670.0 63445.0 True False 60029.99856354661 63849.83861115568 64354.15344666243 61938.890850802636 61967.87378549308 59980.25795569302 49227.06842824844 54107.73415475979 53348.31275514476 61223.80986115503 0.9805008655894532 1.0428922792612225 1.0511295130539324 1.0116797858752875 1.0121531790658806 0.979688426638555 0.8040510471316125 0.8837694726523347 0.8713654520378505 1.0 15.901805203845472 -7.0632967466862615 5.448150260650882 0.880281299643837 1.0201967837910553 0.6137353918482493 0.04847038938365209 0.13033221841935028 7.732805026468012 0.017865074729861995 0.013958455288096711 8.643771014782361e-08 7.0632967466862615 0.13991548414721833 SAHVTVSGGT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 SAHVTVSGGTPK 12 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6;Q9BXS6-7 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 SAHVTVS(0.001)GGT(0.999)PK 76.574 0.038808999999999996 5834900.0 19030.0 19487.0 64954.0 100100.0 67239.0 61932.0 33724.0 87689.0 57782.0 71762.0 True False 25081.144151410448 25785.79166094526 64092.66751981036 77023.49152958347 57904.025479623706 58059.382249605034 36725.37066795532 74138.67994275858 60836.23855570905 69249.63422265288 0.36218450007647734 0.37235996912327707 0.9255307734007413 1.1122584601954129 0.8361636293045168 0.8384070602153838 0.5303330635635581 1.0706003111061402 0.8785062800491783 1.0 16.079518830399962 -5.258797107674219 24.543109693418916 0.8915414822195091 0.3672721520755333 0.662430604831214 0.15174971553091335 105.93843060357848 984004.9155014091 0.04071124629920161 0.09801880771197415 5.51065081124525e-06 5.258797107674219 -0.5242693301439758 SAHVTVSGGT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAHVTVSGGTPK 12 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6;Q9BXS6-7 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 SAHVTVSGGT(1)PK 112.03 0.0021014 3143100.0 25223.0 40571.0 51978.0 61579.0 75551.0 62742.0 50311.0 40140.0 49289.0 44381.0 True False 29492.755723041882 44598.62075560187 53217.35264766269 58128.92827181166 60747.32389739149 59451.69906902152 45545.17785990298 39086.36753184551 50009.758379373176 52426.923980197294 0.5625498023531171 0.8506816225275331 1.0150767698628276 1.1087609926107458 1.158704712874953 1.1339917461394 0.8687364125560048 0.7455399738235495 0.9538945752045813 1.0 15.678020281331627 -4.827819425771126 2.4244179566766864 0.998214134635357 0.48801317571903574 0.5580790136618603 0.11830570022668839 0.42613797788209634 3.3996812113913193 0.03643295932444745 0.44389329443362957 1.4865536042554002e-05 4.827819425771126 -0.5102009589163212 SAHVTVSGGT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 SAHVTVSGGTPK 12 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6;Q9BXS6-7 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 SAHVT(0.01)VS(0.137)GGT(0.853)PK 95.751 0.0094333 3842700.0 37920.0 39458.0 104270.0 43758.0 64210.0 77967.0 54828.0 54818.0 75990.0 44001.0 True False 37379.25384632368 39366.63742529232 95697.32309383966 46976.10929240888 60433.294041717076 74632.53315995395 57666.72556453563 57365.04440294783 67431.20598982516 51606.51422235293 0.7243127037271035 0.7628230276448509 1.8543651811381043 0.9102747976739256 1.171040031522627 1.4461843487120758 1.1174311311954057 1.111585335056415 1.30664136119114 1.0 15.655265566188444 -5.048628535030872 24.998766246467788 1.2375424599989142 0.7339374358316374 0.3861127309476532 0.2504224521534432 313.5044151244081 161164.95998505774 0.06039544901855846 0.1597987913203866 8.940698813045081e-06 5.048628535030872 -0.5036050241672768 SAILVPS(ph)EK ddPTM_PC-9_AZD4547_30min_R2 1 SAILVPSEK 9 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 SAILVPS(1)EK 69.26100000000001 0.040841 4663700.0 48413.0 48604.0 43210.0 64983.0 53703.0 56947.0 46136.0 63671.0 58774.0 65620.0 True False 63807.326947043344 64314.29249697664 42637.00716708757 50002.17332734185 46247.265431256164 53386.0950876487 50242.01462272522 53832.109964025 61880.67365050087 63322.66377317345 1.007653865851348 1.0156599338169865 0.6733293362360203 0.789641028154681 0.7303430190005485 0.8430803744909043 0.7934286340621408 0.8501239012442002 0.9772278985634921 1.0 15.950434325667546 -8.266024272227291 3.606762031231697 0.9979116400153755 0.8305568154474137 0.26044902332074116 0.10180734709800025 0.33317223567313947 8.999896362650686 0.09767491239760498 0.028345042583156295 5.4197059943147815e-09 8.266024272227291 -0.1673548245679618 SAILVPS(ph)EK ddPTM_PC-9_Lapatinib_30min_R1 1 SAILVPSEK 9 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 SAILVPS(1)EK 86.911 0.011298 5511600.0 88683.0 79869.0 76966.0 74406.0 69040.0 58263.0 56121.0 52651.0 51988.0 35401.0 True False 87418.36415752968 79684.0682376369 70638.15257735178 79878.06545113977 64979.20293786254 55771.22730768656 59026.67077783807 55097.35767192536 46132.56398209012 41520.01568113259 2.1054511353967067 1.9191724022842003 1.7013036102838222 1.9238447804208743 1.5650091136018094 1.3432371446099904 1.4216437496352106 1.327007149878379 1.1110921618233771 1.0 15.341519368117304 -6.199289289517297 0.30715037618138363 0.9577000041591242 2.379443487786258 0.9212164335246219 0.0976808100856339 0.858342403940506 0.1291793656014743 0.12855865108614867 0.4342550781393577 6.319907334307421e-07 6.199289289517297 1.4217434836271337 up SAIT(ph)TTINPRFQEADSPTL ddPTM_PC-9_Lapatinib_30min_R1 1 SAITTTINPRFQEADSPTL 19 1 P26010-2;P26010 P26010-2 ITGB7 Integrin beta-7 1 S(0.008)AIT(0.863)T(0.065)T(0.065)INPRFQEADSPTL 55.912 0.021525 8308900.0 9459.1 9051.0 15659.0 7898.6 10617.0 12588.0 8704.3 11143.0 13753.0 10443.0 True False 9324.211499413508 9030.042965591785 14371.577465488015 8479.489392957184 9992.528933825117 12049.640584061219 9154.966063532998 11660.744459521464 12203.992314489595 12248.058635577181 0.7612807692093574 0.7372632050733362 1.1733759523115448 0.6923129326248195 0.8158459418866283 0.9838000406905619 0.7474626253780648 0.9520483863173439 0.9964021791208947 1.0 13.580265474182832 -7.978754912128155 19.839084358512608 0.9902094234720346 0.8512900268631935 0.1862273614649349 0.13410680982136036 37.351050926806586 34878.4778325806 0.07241410449389099 0.03476466062577986 1.0501348900505078e-08 7.978754912128155 -0.138919396608841 SAKS(ph)EESLTSLHAVDGDSK ddPTM_PC-9_Lapatinib_30min_R1 1 SAKSEESLTSLHAVDGDSK 19 1 A7KAX9;A7KAX9-2;G3V174 A7KAX9 ARHGAP32 Rho GTPase-activating protein 32 1 S(0.174)AKS(0.396)EES(0.234)LT(0.059)S(0.137)LHAVDGDSK 48.51 0.033973 8828500.0 29269.0 22542.0 47686.0 28523.0 37788.0 44644.0 30929.0 32167.0 44816.0 24325.0 True False 28851.618692722775 22489.80538397635 43765.44115328319 30620.676569938703 35565.38413406643 42734.68019024699 32530.352283240733 33661.59625140688 39768.35014659823 28529.54383897488 1.0112891694155972 0.7882988074016275 1.5340392892470363 1.0732970966085715 1.2466159408227102 1.4979096907909946 1.1402338735889725 1.1798855404558197 1.393935716990671 1.0 14.800169059293829 -5.244874908967405 24.976094542126734 1.2619890653002994 0.8997939609809216 0.4081075132207428 0.1726229410220121 743.4103833062976 1120918.2886465485 0.041485742527481925 0.10909510281648259 5.690168027152062e-06 5.244874908967405 -0.36219510431937785 SALALAIK ddPTM_PC-9_Lapatinib_30min_R1 2 SALALAIK 8 0 P25789;H0YN18;H0YMI6;H0YMA1;H0YMZ1;H0YL69;P25789-2;H0YKT8;H0YKS0 P25789 PSMA4 Proteasome subunit alpha type-4;Proteasome subunit alpha type;Proteasome subunit beta type 0 ; 104.37 0.012866999999999998 1827100.0 51901.0 48109.0 47855.0 42451.0 40958.0 43359.0 44931.0 43068.0 46753.0 39817.0 False True 51160.8822225223 47997.606566308175 43920.54662564206 45572.98815238467 38548.93096652624 41504.63664476566 47257.30733092856 45069.096507463924 41487.184809084 46699.31539718246 1.095538163405475 1.0278010749854387 0.9404965844165663 0.9758812900099657 0.8254710082720408 0.8887632782571753 1.011948610573845 0.9650911608477907 0.8883895718005981 1.0 15.511113780012666 -5.002464383282546 1.6768634655325878 0.9315784432806418 1.1188220859593827 0.4811137733070009 0.05399552098537029 0.559777134297388 2.143105932761757 0.016034259571787415 0.14861755244331737 9.943416170849443e-06 5.002464383282546 0.18724364267874094 SALAPNLLT(ph)SGK ddPTM_PC-9_Lapatinib_30min_R1 1 SALAPNLLTSGK 12 0 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 SALAPNLLT(0.5)S(0.5)GK 188.63 0.00063107 7147200.0 103160.0 81349.0 89751.0 82177.0 71557.0 68595.0 58069.0 50687.0 69992.0 59085.0 True False 101688.91948277301 81160.64138856756 82372.01922887893 88220.57071443602 67348.15794647492 65661.35175275493 61075.52868620086 53042.10306199088 62108.76391156519 69297.76352418632 1.467419932640128 1.1711870233768924 1.1886677872386089 1.273065193274892 0.9718662554379415 0.9475248321663049 0.8813492034975164 0.7654230146039 0.8962592838928775 1.0 16.080521171960555 -6.357900702618751 1.275172291876277 0.865820817439161 1.2916567641451848 0.7779427994682212 0.09538038290465564 0.2007889717908962 0.6691111293476824 0.038851818915562795 0.05083450340188962 4.3863097519078045e-07 6.357900702618751 0.42583594670602387 SALAPNLLTS(ph)GK ddPTM_PC-9_AZD4547_30min_R2 2 SALAPNLLTSGK 12 0 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 SALAPNLLT(0.211)S(0.789)GK;SALAPNLLT(0.08)S(0.92)GK 156.2 0.00035809 18953600.0 136054.0 118119.0 138804.0 159884.0 166580.0 150194.0 128262.0 151427.0 148740.0 164567.0 True False 179316.3419009982 156298.65680706056 136963.36826707746 123025.2139831758 143453.24238010249 140802.34543688496 139677.06952358186 128027.43659629059 156602.0927412715 158805.55942029657 1.129156577109606 0.9842140122651423 0.8624595308064038 0.7746908510776748 0.9033263249962019 0.8866336037029781 0.879547731411033 0.8061898907295288 0.9861247510032483 1.0 17.2769018932634 -4.910284791137816 2.5638087890027603 0.8771888204885533 1.1481999005668366 0.5565375840275095 0.06627030469526142 0.2550405035551386 2.6783752825532994 0.016733113284947414 0.13447755051480703 1.2294622793548743e-05 4.910284791137816 0.27101108007828334 SALAPNLLTS(ph)GK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SALAPNLLTSGK 12 0 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 SALAPNLLT(0.415)S(0.585)GK;SALAPNLLT(0.366)S(0.634)GK 113.52 0.00082372 12776800.0 168973.0 161179.0 160361.0 168722.0 151884.0 136169.0 157353.0 138566.0 122834.0 94731.0 True False 197576.79153112497 177179.78592509846 164184.61441247942 159269.05334410412 122123.42050841713 129028.05792817558 142447.3847029341 134928.78932281304 124630.21487090248 111904.98040981645 1.7655763917527416 1.5833056337281306 1.4671787958963527 1.4232525912683403 1.0913135417313768 1.1530144364947057 1.272931590544637 1.2057442736568043 1.113714639102602 1.0 16.77191472033691 -1.522878753439314 0.2980897595045518 1.06868577653916 7.2862012182748765 0.8873270172634967 0.07793420768944127 18.02841171328274 0.25675551403144437 0.08718779623769889 59.640634348660726 0.02999999943639788 1.522878753439314 6.217515441735717 SALAPNLLTS(ph)GK ddPTM_PC-9_Lapatinib_30min_R1 1 SALAPNLLTSGK 12 0 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 SALAPNLLT(0.167)S(0.833)GK 128.73 0.00019622 6584900.0 81857.0 65879.0 69891.0 62485.0 48804.0 56679.0 50977.0 39427.0 58386.0 40403.0 True False 80689.70416926463 65726.46122309365 64144.83176706184 67080.3553438495 45933.44467235573 54254.9712952022 53616.339627623354 41258.92235533993 51809.95384816332 47386.604716386515 1.7027956455669369 1.3870261778929505 1.353649035438917 1.4155974192566025 0.9693339488505646 1.1449432095826138 1.1314661590236823 0.8706874569781615 1.0933459815965079 1.0 15.532191674106947 -4.29969194289717 0.3834997572924498 0.970455006555334 2.4584691307210877 0.7924837326535958 0.10953384937146111 3.7578942359029046 0.33024465115090146 0.09116011643831846 2.7677467694803406 5.015428657262821e-05 4.29969194289717 1.4880141241657538 SALAPNLLTS(ph)GKK ddPTM_PC-9_Lapatinib_30min_R1 1 SALAPNLLTSGKK 13 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 SALAPNLLT(0.261)S(0.739)GKK 73.597 0.0095884 8435300.0 51176.0 41142.0 46939.0 44385.0 37179.0 41079.0 30864.0 29125.0 38836.0 31678.0 True False 50446.220855471 41046.73822675695 43079.856609779796 47649.220964019514 34992.204316726384 39322.14692982609 32461.986901288168 30478.253826039887 34461.88071878994 37153.50009171827 1.3577784254764131 1.104787923760284 1.1595100462522114 1.282496153697261 0.9418279362736635 1.0583699202700751 0.8737262120971513 0.8203333131683511 0.9275540832954171 1.0 15.18121050759749 -6.501823743161733 1.3758873774575402 0.9007038097378949 1.2195310340580525 0.674689719477137 0.09489080751867002 0.2446013356015295 0.9529659680474207 0.03911011078622812 0.0443735310280051 3.149026075592909e-07 6.501823743161733 0.31882722432015764 SALNLNQPVSVSSVS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 2 SALNLNQPVSVSSVSPVK 18 0 H0YIT6;G3V1N3;Q86XJ1 H0YIT6 GAS2L3 GAS2-like protein 3 1 SALNLNQPVSVS(0.065)S(0.216)VS(0.719)PVK;SALNLNQPVSVSS(0.006)VS(0.993)PVK 197.67 1.2020999999999999e-14 10870700.0 39642.0 66934.0 59251.0 44811.0 61187.0 61666.0 54210.0 58750.0 52950.0 41610.0 True False 39076.69781054756 66779.01843541273 54379.61149547418 48106.550425113885 57588.1009582704 59028.688930467026 57016.72854843289 61479.73947741952 46986.21341178104 48802.23305816011 0.8007153640690552 1.3683598936103756 1.1142853121222387 0.9857448606456769 1.1800300385771225 1.2095489331424552 1.168322123302906 1.259773080550453 0.9627881854460465 1.0 15.574659542670114 -4.734727870367929 24.938889709853658 1.1457581585900396 0.8007135538952312 0.40632986151833017 0.12232014417927006 2763.378621556673 2579856.362931418 0.02943877466798703 2.5490996379997304 1.8419257936594922e-05 4.734727870367929 -0.34504460469480835 SALPVSPSIS(ph)SAPVPVEIENLPQSPGTDQHDRK ddPTM_PC-9_AZD4547_30min_R2 1 SALPVSPSISSAPVPVEIENLPQSPGTDQHDRK 33 1 Q9HCM4-2;Q9HCM4-4;Q9HCM4-3;Q9HCM4 Q9HCM4-2 EPB41L5 Band 4.1-like protein 5 1 S(0.014)ALPVS(0.135)PS(0.031)IS(0.409)S(0.409)APVPVEIENLPQS(0.001)PGTDQHDRK 71.29899999999999 4.258e-06 4356600.0 9921.2 11273.0 15808.0 22726.0 21100.0 21331.0 17070.0 22735.0 19211.0 16235.0 True False 13075.935226220365 14916.776794469943 15598.37559123629 17486.871813199912 18170.629212511496 19997.169197932002 18589.19693102827 19221.828148326702 20226.454239966184 15666.617591549408 0.8346367778373259 0.9521376715364566 0.9956441139949744 1.1161868036296712 1.159831029660975 1.276419053511493 1.18654820176726 1.2269290442561755 1.2910543148047704 1.0 13.935406116435216 -5.555409078296142 1.0384699392057046 1.2112367153698476 0.8369031754613869 0.7079920620629643 0.07795022977472794 0.3552413224499582 0.6533072726215775 0.027019129289023145 0.11174129008100771 2.783498051980345e-06 5.555409078296142 -0.37433353990846063 SALPVSPSISSAPVPVEIENLPQS(ph)PGTDQHDR ddPTM_PC-9_Lapatinib_30min_R1 2 SALPVSPSISSAPVPVEIENLPQSPGTDQHDR 32 0 Q9HCM4-2;Q9HCM4-4;Q9HCM4-3;Q9HCM4 Q9HCM4-2 EPB41L5 Band 4.1-like protein 5 1 SALPVSPSIS(0.001)S(0.001)APVPVEIENLPQS(0.637)PGT(0.362)DQHDR;SALPVSPSISSAPVPVEIENLPQS(0.973)PGT(0.027)DQHDR 88.43299999999999 7.6844e-08 1990100.0 8366.9 10577.8 11041.4 8447.8 12557.0 13870.2 14179.3 10149.400000000001 15080.3 11365.2 True False 8247.586471698458 10553.307753998093 10133.618713036552 9069.079393034675 11818.421948011865 13277.003879015401 14913.434774152254 10620.978176206327 13381.797811400966 13329.65967682291 0.6187394630966488 0.7917162185579104 0.7602308655078788 0.6803684124661964 0.8866259330357303 0.9960497267684137 1.1188158689514895 0.7967928989720321 1.0039114377892717 1.0 13.702352326605928 -6.447883402951679 3.5067604193381583 0.9773821117919946 0.7224181699127663 0.6870016957826259 0.08582178769612747 0.15205072688946433 3.6043863816036636 0.028462889823482756 0.03171717697802099 3.565468443581501e-07 6.447883402951679 -0.25496394187922833 SALPVSPSISSAPVPVEIENLPQS(ph)PGTDQHDRK ddPTM_PC-9_Lapatinib_30min_R1 1 SALPVSPSISSAPVPVEIENLPQSPGTDQHDRK 33 1 Q9HCM4-2;Q9HCM4-4;Q9HCM4-3;Q9HCM4 Q9HCM4-2 EPB41L5 Band 4.1-like protein 5 1 SALPVSPSISSAPVPVEIENLPQS(0.649)PGT(0.35)DQHDRK 65.73 1.294e-05 2757100.0 21622.0 14337.0 12543.0 11750.0 17318.0 18834.0 15844.0 15143.0 23006.0 16518.0 True False 21313.666315010814 14303.80355736266 11511.762957380166 12614.134196850955 16299.389288498007 18028.51372419836 16664.324794712593 15846.59906223939 20414.822016079957 19373.11429114849 1.1001672727832383 0.7383326884050863 0.5942133404250782 0.6511154586340467 0.8413406870750327 0.9305945060384808 0.8601779014087821 0.8179685942120131 1.0537707933415446 1.0 14.24176827005471 -6.520920415556989 5.538386744512574 0.914398932517878 0.7543798442898741 0.22113462653001514 0.13981651613616872 0.27204799431365895 28.877816732476933 0.0473125294809921 0.049929745668384 3.0135582079880466e-07 6.520920415556989 -0.16001908822800381 SALPVSPSISSAPVPVEIENLPQSPGT(ph)DQHDRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SALPVSPSISSAPVPVEIENLPQSPGTDQHDRK 33 1 Q9HCM4-2;Q9HCM4-4;Q9HCM4-3;Q9HCM4 Q9HCM4-2 EPB41L5 Band 4.1-like protein 5 1 SALPVSPSISSAPVPVEIENLPQS(0.406)PGT(0.594)DQHDRK 94.837 4.5673e-15 3670500.0 16940.0 16775.0 20694.0 23671.0 38712.0 35306.0 36063.0 43214.0 37547.0 30736.0 True False 19807.607419748998 18440.3111378872 21187.42344243204 22344.79061241744 31126.661496417215 33454.49120733917 32646.851566490077 42079.67828901775 38096.05384305475 36308.19349395787 0.5455409788714832 0.507882914663763 0.5835438616894527 0.6154200598312854 0.857290283571863 0.9214033524666108 0.8991593473776908 1.1589581920681435 1.049241236675529 1.0 15.148007530504325 -6.466200851183055 0.8978875260426177 1.0606498519015908 0.5065107921084174 0.9259880249088491 0.060092823058395126 0.14164764564936902 0.24947966421782583 0.03297303432358932 0.04224293877291585 3.418213214740732e-07 6.466200851183055 -0.5541390597931733 SALSPSKS(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 1 SALSPSKSPAK 11 1 P49792;Q7Z3J3 P49792 RANBP2;RGPD4 E3 SUMO-protein ligase RanBP2;RanBP2-like and GRIP domain-containing protein 4 1 S(0.001)ALS(0.025)PS(0.084)KS(0.89)PAK 108.23 0.01067 19677000.0 27724.0 21233.0 24993.0 20134.0 28708.0 24288.0 27577.0 29468.0 25013.0 27096.0 True False 36539.655304976535 28096.15201605431 24661.576489863903 15492.417367199114 24722.389736150737 22769.267520480644 30031.299576272206 24914.397707274748 26335.136114948415 26147.377287380525 1.3974501114730014 1.074530409197649 0.9431759146936044 0.5925036839039378 0.9455017023096413 0.8708050245433123 1.1485396506962928 0.9528449998424565 1.0071807900847671 1.0 14.674378623755922 -4.814868711289075 2.4239506961926134 0.9262326325670243 1.4844124618125842 0.5283522567367205 0.13323068580233563 0.4195584797278088 3.2662801805963655 0.0372513611045172 0.48378334759252306 1.531550384639338e-05 4.814868711289075 0.55817982924556 SALSS(ph)SLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SALSSSLR 8 0 A0A0C4DGT3;A0A3B3IU98;Q6DN90-2;A0A2R8Y7T6;A0A3B3IRZ4;Q6DN90;Q6DN90-3 A0A0C4DGT3;A0A2R8Y7T6 IQSEC1 IQ motif and SEC7 domain-containing protein 1 1 SALS(0.043)S(0.864)S(0.093)LR 85.86200000000001 0.012908000000000001 13569000.0 56905.0 78288.0 68697.0 59522.0 72603.0 53672.0 66945.0 47437.0 48176.0 42390.0 True False 66537.89257501878 86059.91525263274 70334.99701482341 56187.17531292768 58376.96333499641 50857.34583584399 60603.484960171816 46191.829013656105 48880.48285996229 50074.97144094463 1.3287654622726948 1.7186213546647062 1.4045938517962455 1.1220610555752668 1.165791245709299 1.015624060731059 1.2102550079662826 0.9224534270205612 0.976145995761754 1.0 15.611802072781256 -5.729364554223303 2.706303228898754 1.0560207390170946 1.534249998539589 0.7325029700597168 0.11952307598643482 0.1294438105849876 1.9292800999003092 0.03411152144510967 0.06274540986649704 1.864813677130764e-06 5.729364554223303 0.4782292595224944 SALSS(ph)SLRDLSEAGVHH ddPTM_PC-9_AZD4547_30min_R2 1 SALSSSLRDLSEAGVHH 17 1 A0A0C4DGT3 A0A0C4DGT3 IQSEC1 1 S(0.002)ALS(0.111)S(0.442)S(0.442)LRDLS(0.004)EAGVHH 60.937 0.014263 15452000.0 12403.0 8379.3 23804.0 40625.0 27195.0 22057.0 15966.0 30618.0 15557.0 22554.0 True False 16346.896001573514 11087.74485885762 23488.343406742697 31259.533899993236 23419.44366986968 20677.772303163758 17386.94306975964 25886.69163164579 16379.311259755033 21764.391324903307 0.7510844552252205 0.5094442887622027 1.0792097539556185 1.4362696127516037 1.076044044616705 0.9500735395941804 0.7988710922443812 1.1894057244792164 0.752573826450798 1.0 14.409682053025938 -5.268912828064104 24.94717306907821 1.0463573974651539 0.6302643660256446 0.41900032153662703 0.19042788624688692 473.612451547555 1580972.8250436627 0.05169510773407245 0.11110639929816635 5.383778353015745e-06 5.268912828064104 -0.41609303143950926 SALSS(ph)SLRDLSEAGVHH ddPTM_PC-9_Lapatinib_30min_R1 2 SALSSSLRDLSEAGVHH 17 1 A0A0C4DGT3 A0A0C4DGT3 IQSEC1 1 SALS(0.031)S(0.484)S(0.484)LRDLSEAGVHH;S(0.002)ALS(0.03)S(0.481)S(0.481)LRDLS(0.007)EAGVHH 78.985 0.0028154 27839000.0 67135.0 37450.0 78673.0 52851.0 56117.0 61285.0 45461.0 45645.0 80080.0 33374.0 True False 66177.64258894871 37363.28682592113 72204.80962656217 56737.838845767605 52816.3083902669 58663.98341231268 47814.74813761864 47765.83333526496 71060.54712021568 39142.65143194032 1.690678586350129 0.9545415412363396 1.8446581155113881 1.4495144495875834 1.349328838443706 1.4987227810644168 1.2215510801754708 1.2203014253727364 1.8154249781411185 1.0 15.256453863622324 -7.239564068381401 24.123598492444238 1.3326777819192044 1.4527443542382315 0.05829594234490654 0.2898156877314448 2044.0215011471614 2254102.615187619 0.10630739286736061 0.08225721502435127 5.760178364699517e-08 7.239564068381401 0.12006657231902707 SALSSS(ph)LR ddPTM_PC-9_AZD4547_30min_R2 1 SALSSSLR 8 0 A0A0C4DGT3;A0A3B3IU98;Q6DN90-2;A0A2R8Y7T6;A0A3B3IRZ4;Q6DN90;Q6DN90-3 A0A0C4DGT3;A0A2R8Y7T6 IQSEC1 IQ motif and SEC7 domain-containing protein 1 1 SALS(0.007)S(0.077)S(0.916)LR 85.67 0.013052000000000001 10542000.0 115190.0 125260.0 145090.0 130830.0 115650.0 169670.0 147610.0 182750.0 158210.0 145990.0 True False 151818.02389915762 165747.84540719466 143166.01179987824 100669.16480335053 99593.99376431077 159060.5080780611 160747.00404153983 154510.18667722485 166572.6576078834 140878.93453589783 1.07764886495839 1.1765268239231317 1.0162343452661309 0.7145792600929892 0.7069473806882951 1.12905814202854 1.1410293850609676 1.0967586260233504 1.1823815828578577 1.0 17.104096377690823 -6.8879793431664575 19.681400774857043 1.1179602942300593 0.9409158712365097 0.2628328178542907 0.14319427217150135 3.4025257685365724 580.0836385056051 0.05748643759060905 0.05069839349452689 1.2942574001963702e-07 6.8879793431664575 -0.1770444229935496 SALSSS(ph)LR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SALSSSLR 8 0 A0A0C4DGT3;A0A3B3IU98;Q6DN90-2;A0A2R8Y7T6;A0A3B3IRZ4;Q6DN90;Q6DN90-3 A0A0C4DGT3;A0A2R8Y7T6 IQSEC1 IQ motif and SEC7 domain-containing protein 1 1 SALS(0.011)S(0.08)S(0.909)LR 83.78299999999999 0.014566999999999998 11085000.0 31061.0 44026.0 47460.0 34352.0 43435.0 31979.0 39559.0 23571.0 27190.0 26609.0 True False 36319.01381728594 48396.61032230234 48591.626393052335 32427.36881068665 34924.223550756426 30301.964944187926 35811.68513764192 22952.2862255389 27587.602311573708 31433.001063271906 1.1554421337046028 1.5396751403050621 1.5458793226660605 1.031634515120372 1.111068697527703 0.9640175585904985 1.1393021323530677 0.730197100154005 0.8776636457983206 1.0 14.93999239945602 -5.835015516755338 5.970160445198016 0.9754515594763419 1.4250767236729371 0.6460267763307628 0.1475823215720212 0.1250021127384583 7.6097332949568814 0.043451448853931846 0.06566534347090872 1.4621249337741458e-06 5.835015516755338 0.44962516419659526 SALSSS(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 2 SALSSSLR 8 0 A0A0C4DGT3;A0A3B3IU98;Q6DN90-2;A0A2R8Y7T6;A0A3B3IRZ4;Q6DN90;Q6DN90-3 A0A0C4DGT3;A0A2R8Y7T6 IQSEC1 IQ motif and SEC7 domain-containing protein 1 1 SALS(0.018)S(0.096)S(0.886)LR;SALS(0.003)S(0.09)S(0.907)LR 82.645 0.016176 28272000.0 299507.0 284760.0 244830.0 234503.0 269390.0 261474.0 246928.0 260046.0 246971.0 220674.0 True False 295235.9752571424 284100.65571560204 224701.02247113016 251749.13289907627 253545.00984111795 250291.3665456643 259712.72361201688 272128.68650459684 219154.52526007488 258817.20687037776 1.140712315178504 1.097688438689808 0.8681842493712798 0.9726908652760426 0.9796296502345755 0.9670584485946353 1.0034600355689938 1.0514319731488557 0.8467540775595845 1.0 17.981574009237683 -5.094579814583099 6.421287382337984 0.9660301992965169 1.1305586852246277 0.5435816393442366 0.05834422645345168 0.15709159476334345 8.74105345931732 0.014479725853974881 0.03974996001422139 8.043039200993303e-06 5.094579814583099 0.16452848592811076 SALVTSSSS(ph)LPSFPSTLSWSR ddPTM_PC-9_AZD4547_30min_R2 1 SALVTSSSSLPSFPSTLSWSR 21 0 F8VXI9;Q14161-6;Q14161-4;Q14161-3;Q14161 F8VXI9 GIT2 ARF GTPase-activating protein GIT2 1 SALVTSS(0.002)S(0.146)S(0.852)LPSFPSTLSWSR 248.01 2.0644999999999996e-61 4270400.0 6693.5 6642.9 12154.0 16545.0 13089.0 13662.0 13177.0 15617.0 10949.0 10443.0 True False 8821.893766551018 8790.08751601032 11992.830018717472 12730.805867701874 11271.81828258592 12807.71298027036 14349.727472768554 13203.751492958787 11527.741787173483 10077.393748601819 0.8754142178651109 0.8722580198109154 1.19007258403309 1.2633034081325047 1.1185251428872491 1.270935055211806 1.423952247053907 1.3102347513999573 1.1439209457080997 1.0 13.298834951706604 -5.293987211930928 4.0774877761296535 1.2372597135520158 0.8669524873748802 0.6025045772974555 0.11024451991902776 0.12829571826633715 4.851228157170985 0.029577200725666324 0.07205505474486444 5.0817440584928964e-06 5.293987211930928 -0.37030722617713563 SALVTSSSS(ph)LPSFPSTLSWSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SALVTSSSSLPSFPSTLSWSR 21 0 F8VXI9;Q14161-6;Q14161-4;Q14161-3;Q14161 F8VXI9 GIT2 ARF GTPase-activating protein GIT2 1 SALVTSSS(0.036)S(0.964)LPSFPSTLSWSR 204.78 1.8142000000000002e-24 2796500.0 6142.1 7036.5 10055.0 11068.0 11029.0 13422.0 11688.0 9306.5 11008.0 7811.5 True False 7181.836217995298 7735.037217391552 10294.749333799846 10447.895842940148 8867.946622338946 12718.126691919388 10580.828026207908 9062.21423605183 11168.97117491002 9227.663114200026 0.7782941497878809 0.8382444310833649 1.115639919489229 1.13223637595334 0.961017595960181 1.3782608374972043 1.146642209978988 0.9820703382751811 1.2103791649830178 1.0 13.171749619378172 -5.224393619045517 3.8886987935361494 1.1221053109574552 0.7923384953572004 0.5300305505489074 0.11621959388335565 0.1657950730773738 5.473452601705666 0.030289514286695553 0.08590522240225514 5.964944139629057e-06 5.224393619045517 -0.3297668156002549 SALVTSSSS(ph)LPSFPSTLSWSR ddPTM_PC-9_Lapatinib_30min_R1 3 SALVTSSSSLPSFPSTLSWSR 21 0 F8VXI9;Q14161-6;Q14161-4;Q14161-3;Q14161 F8VXI9 GIT2 ARF GTPase-activating protein GIT2 1 SALVTSSS(0.032)S(0.961)LPS(0.005)FPS(0.001)T(0.001)LSWSR;SALVTSSS(0.021)S(0.979)LPSFPSTLSWSR;SALVTS(0.016)S(0.047)S(0.2)S(0.734)LPS(0.002)FPSTLSWSR 221.81 8.8081e-33 4955900.0 34968.6 36687.3 34445.9 27750.8 33699.2 34464.3 29706.7 32301.100000000002 34325.9 27524.699999999997 True False 34469.941351544134 36602.35281091101 31613.89106701917 29791.686405955024 31717.079311176345 32990.34222920724 31244.76757000056 33801.92702696302 30459.755674248405 32282.307720642653 1.0677657139580086 1.1338208261829417 0.9792946446267821 0.9228487214656274 0.9824910779502645 1.0219325865638733 0.9678604094967274 1.047072821418794 0.9435433159808203 1.0 14.978456093794765 -5.270177627840644 24.951893061816577 0.9834762941625114 1.1007932708845007 0.6211345516779752 0.03675695361550175 342.21521341900734 977190.7438410232 0.009548624751693621 0.02041000338969694 5.368121935495781e-06 5.270177627840644 0.11731697672198937 SAMDSPVPASMFAPEPS(ph)SPGAAR ddPTM_PC-9_AZD4547_30min_R2 1 SAMDSPVPASMFAPEPSSPGAAR 23 0 O00178;F8WAZ4 O00178 GTPBP1 GTP-binding protein 1 1 SAMDSPVPASMFAPEPS(0.5)S(0.5)PGAAR 95.646 4.7882e-06 14089000.0 21138.0 28692.0 35752.0 54761.0 43594.0 34378.0 33230.0 42482.0 37742.0 38133.0 True False 27859.444302286607 37966.12789735933 35277.9051200582 42136.69749901615 37541.72558721453 32228.3382254234 36187.405624960105 35917.383039244094 39736.96506817988 36797.97527678185 0.7570917718362857 1.0317450243332964 0.9586914729603954 1.1450819557890957 1.0202117183034785 0.8758182476892493 0.983407520461948 0.9760695464651454 1.0798682473503487 1.0 15.167338767067967 -4.75772557506823 24.936172011338684 1.0053738110501227 0.7570914064634686 0.5497259311069382 0.06805690516752862 84.26773274850275 565726.1529312057 0.017559773850393028 0.1270522441830841 1.746925663429201e-05 4.75772557506823 -0.24828240458665407 SAMDSPVPASMFAPEPS(ph)SPGAAR ddPTM_PC-9_Lapatinib_30min_R1 3 SAMDSPVPASMFAPEPSSPGAAR 23 0 O00178;F8WAZ4 O00178 GTPBP1 GTP-binding protein 1 1 SAMDSPVPAS(0.16)MFAPEPS(0.42)S(0.42)PGAAR;SAMDSPVPAS(0.111)MFAPEPS(0.444)S(0.444)PGAAR;SAMDSPVPAS(0.002)MFAPEPS(0.63)S(0.369)PGAAR 152.47 1.1104e-06 42424000.0 123055.0 107122.0 116179.0 95898.0 111281.0 113593.0 97218.0 103039.0 121895.0 80916.0 True False 121300.2131344767 106873.96559055625 106627.21108390916 102950.65882635022 104735.67036686365 108734.8921882163 102251.47234867267 107826.56810236291 108165.90148874487 94902.22278620735 1.2781598741658338 1.1261481812846308 1.1235480893225809 1.0848076662890618 1.1036166202640878 1.14575706443853 1.0774402258103213 1.136185907312952 1.1397615178352303 1.0 16.53415425778723 -4.723724774696588 3.044882756333812 1.106921080492838 1.3206927954424905 0.6243673669465135 0.040689222133432235 0.3097506351130762 3.6434645254107805 0.009630141389662445 0.1735782416293669 1.8891882044527335e-05 4.723724774696588 0.21377171494965252 SAMDSPVPASMFAPEPSS(ph)PGAAR ddPTM_PC-9_AZD4547_30min_R2 2 SAMDSPVPASMFAPEPSSPGAAR 23 0 O00178;F8WAZ4 O00178 GTPBP1 GTP-binding protein 1 1 SAMDSPVPASMFAPEPS(0.227)S(0.773)PGAAR;SAMDSPVPASMFAPEPS(0.226)S(0.774)PGAAR 310.24 2.379499999999999e-161 23366000.0 68401.0 57445.0 85108.0 129558.0 105845.0 96239.0 74642.0 98830.0 72958.0 88536.0 True False 90151.0951708158 76012.97285179871 83979.41231142062 99690.40475114655 91150.24876769091 90221.16011625239 81284.9933992859 83558.09438746984 76814.41093329094 85436.38158826121 1.0551839098860243 0.8897026236214426 0.9829467347544973 1.1668378610833374 1.0668786186073074 1.0560039931355027 0.9514095972722503 0.9780153704326654 0.8990831482479952 1.0 16.382562926677743 -7.269692664901355 23.80557373580587 0.9552949649756256 1.0345012304399566 0.23519481211077176 0.06983233272946489 557.4642321827861 1607924.8757985448 0.031610684934136594 0.021750522232037686 5.3741196959462013e-08 7.269692664901355 0.07920626546433096 SAMDSPVPASMFAPEPSS(ph)PGAAR ddPTM_PC-9_Lapatinib_30min_R1 6 SAMDSPVPASMFAPEPSSPGAAR 23 0 O00178;F8WAZ4 O00178 GTPBP1 GTP-binding protein 1 1 SAMDSPVPASMFAPEPS(0.124)S(0.875)PGAAR;SAMDSPVPAS(0.001)MFAPEPS(0.038)S(0.961)PGAAR;SAMDSPVPASMFAPEPS(0.053)S(0.947)PGAAR;SAMDSPVPAS(0.019)MFAPEPS(0.24)S(0.741)PGAAR;SAMDSPVPAS(0.004)MFAPEPS(0.085)S(0.91)PGAAR;SAMDSPVPASMFAPEPS(0.199)S(0.801)PGAAR 234.72 1.3254e-57 36409300.0 189138.0 152529.0 158633.0 146078.0 155018.0 160377.0 149228.0 144475.0 170381.0 114034.2 True False 186440.857436339 152175.82847185375 145590.80708108805 156821.06342192256 145900.14601711414 153518.0495670469 156954.29566178835 151187.83593191786 151190.8975885298 133744.85952897999 1.3940039123218846 1.137806933348942 1.0885712362615423 1.1725389968198545 1.0908841396293092 1.1478426169626537 1.1735351640021672 1.1304197893240024 1.1304426810943682 1.0 17.029123917168796 -4.76226241471103 5.69384280982961 1.1248473378408157 1.4056456260095391 0.7444990986897075 0.048264380074464534 0.06704465606146712 7.437992793949196 0.011096661120308667 0.07397631812182362 1.728771464179069e-05 4.76226241471103 0.28079828816872343 SAMPFT(ph)ASPASSTTAR ddPTM_PC-9_AZD4547_30min_R2 1 SAMPFTASPASSTTAR 16 0 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 1 SAMPFT(0.487)AS(0.487)PAS(0.026)STTAR 149.35 7.4807e-05 16277000.0 23853.0 22430.0 30818.0 52990.0 40222.0 30149.0 25040.0 27822.0 25360.0 26883.0 True False 31437.757826778437 29680.058857443535 30409.33318387651 40773.974187338885 34637.86958225772 28263.7782639563 27268.511491092406 23522.749185957557 26700.47782653388 25941.834352548376 1.2118556228345576 1.1441002380206755 1.172212140846134 1.571745992716721 1.3352128115356305 1.089505772022626 1.051140452155948 0.9067496487058101 1.0292440181243767 1.0 14.662992876014869 -6.946684624487135 3.277679610841022 0.9938260404637812 1.2876804736179042 0.5822852337706734 0.1167297384050466 0.19980588609219943 4.395985484623983 0.049917104404743194 0.042102705961574075 1.130616646652125e-07 6.946684624487135 0.29385443315412296 SAMPFT(ph)ASPASSTTAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAMPFTASPASSTTAR 16 0 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 1 S(0.001)AMPFT(0.529)AS(0.466)PAS(0.001)S(0.002)T(0.001)T(0.001)AR 77.124 0.041585000000000004 31027000.0 74960.0 64277.0 83172.0 77492.0 89376.0 67449.0 83482.0 67960.0 56408.0 49960.0 True False 87649.24747251386 70657.99576810595 85155.1359115665 73150.37447245355 71863.41439098427 63911.85570282152 75573.9806026599 66176.12200957193 57232.860286548355 59017.35251685758 1.4851436693551772 1.1972410275083647 1.442883021349407 1.2394723136989083 1.2176658444727315 1.082933289570485 1.2805383057647854 1.1212994007257364 0.9697632619186111 1.0 15.848851583334117 -6.128555129776564 0.26413210347156935 0.9605920218673609 1.5548836294363826 0.6451226811704169 0.0963208437046024 2.962725362331467 0.3205518170081556 0.14802767182020854 0.5647458610968061 7.437806406550987e-07 6.128555129776564 0.5942916075690217 SAMPFT(ph)ASPASSTTAR ddPTM_PC-9_Lapatinib_30min_R1 1 SAMPFTASPASSTTAR 16 0 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 1 S(0.001)AMPFT(0.278)AS(0.194)PAS(0.01)S(0.125)T(0.125)T(0.268)AR 84.352 0.019074 24247000.0 47837.0 41994.0 47897.0 43516.0 37066.0 42444.0 31072.0 30395.0 36376.0 28156.0 True False 47154.835607768626 41896.7654731037 43959.093547766715 46716.311805120524 34885.85075455984 40628.769061796476 32680.75612353634 31807.26266240285 32278.951823738378 33022.72708448828 1.4279509831857164 1.268725183293048 1.331176962923076 1.414671528659561 1.0564194369927347 1.2303274940875786 0.9896443755212277 0.9631930936843683 0.9774768674056821 1.0 15.011171645433857 -6.74110621697079 0.9320200081379852 0.9662531192564586 1.3624568584937786 0.7890579898600059 0.08212928978544937 0.24479413970911038 0.46043576895111055 0.04786764288930363 0.04501571130088673 1.815071689841254e-07 6.74110621697079 0.39620373923732 SAMPFTAS(ph)PASSTTAR ddPTM_PC-9_AZD4547_30min_R2 3 SAMPFTASPASSTTAR 16 0 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 1 SAMPFT(0.367)AS(0.533)PAS(0.007)S(0.071)T(0.02)T(0.001)AR;S(0.001)AMPFT(0.173)AS(0.82)PASS(0.005)TTAR;SAMPFT(0.045)AS(0.659)PAS(0.022)S(0.206)T(0.064)T(0.003)AR 133.23 3.3036e-06 403702000.0 100135.0 106183.0 127425.0 178947.0 159528.0 129461.0 100616.0 167822.0 128279.0 130658.0 True False 131975.8470626111 140504.57822826237 125735.26124198404 137693.5338535899 137380.29085372225 121365.78320441976 109570.62908098039 141888.9660659107 135059.566053231 126083.70318919994 1.046732002030187 1.1143754083541044 0.9972364235947843 1.0920803432222195 1.089595938085438 0.9625810484190767 0.8690308605273103 1.1253553193388803 1.0711897147449896 1.0 16.94402228818761 -6.749550162667884 24.95304654862252 1.004928558671011 1.0679862543031164 0.1689287969694072 0.06916334299321832 438.81512189528246 920982.5044081857 0.024363126208436683 0.02418173327421773 1.7801222860702394e-07 6.749550162667884 0.06305769563210539 SAMPFTAS(ph)PASSTTAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SAMPFTASPASSTTAR 16 0 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 1 SAMPFT(0.17)AS(0.785)PAS(0.009)S(0.021)T(0.007)T(0.007)AR;SAMPFT(0.192)AS(0.645)PAS(0.024)S(0.054)T(0.054)T(0.031)AR;SAMPFT(0.308)AS(0.669)PAS(0.001)S(0.013)T(0.004)T(0.004)AR 145.94 2.6183000000000003e-05 307594000.0 296351.0 297611.0 295377.0 318350.0 335029.0 296004.0 292474.0 243999.0 275259.0 239334.0 True False 346517.3711009464 327155.8532374224 302419.9079035101 300513.8816046258 269382.4724758001 280481.02915473934 264768.74539161 237594.2847883106 279284.1421361341 282723.35963309783 1.2256411056753032 1.157158904952129 1.069667212132642 1.062925546706206 0.952812929307961 0.9920688177967733 0.9364940545953179 0.8403772687783805 0.9878353967587716 1.0 18.10903156324632 -5.344450456395488 0.6732657734732271 0.930776882158158 1.2969864679609628 0.8132006387683823 0.045599812628869474 0.6837466962716784 0.3824532339729221 0.022497005251192397 0.17229607614051826 4.524280716434757e-06 5.344450456395488 0.3662095858028048 SAMPFTAS(ph)PASSTTAR ddPTM_PC-9_Lapatinib_30min_R1 3 SAMPFTASPASSTTAR 16 0 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 1 S(0.003)AMPFT(0.14)AS(0.501)PAS(0.064)S(0.172)T(0.061)T(0.061)AR;SAMPFT(0.177)AS(0.815)PAS(0.001)S(0.005)T(0.002)T(0.002)AR;SAMPFT(0.171)AS(0.775)PAS(0.003)S(0.028)T(0.022)T(0.001)AR 125.61 2.7431999999999998e-05 254165000.0 353640.0 333555.0 350750.0 311451.0 289288.0 325011.0 271400.0 272937.0 317978.0 218580.0 True False 348597.028750367 332782.67389105837 321912.68893415364 334356.1455100792 272272.64860209083 311111.0371676451 285451.764029601 285618.6494255063 282163.96918321605 256361.26176045754 1.3597882392859106 1.298100468088695 1.2556994248021254 1.304238180191591 1.0620662682511712 1.213564931890316 1.11347464148591 1.114125618918145 1.1006497910236859 1.0 17.967818750089293 -1.5228787452803376 0.15330263183263215 0.9671212386551532 2.472814681215614 0.7994159509674179 0.05104228064070874 27.902839746777133 0.2799392794899949 0.1659184876247473 9.386317792337922 0.029999999999999995 1.5228787452803376 1.5056934425604611 SAMPFTASPASS(ph)TTAR ddPTM_PC-9_AZD4547_30min_R2 1 SAMPFTASPASSTTAR 16 0 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 1 S(0.001)AMPFT(0.039)AS(0.027)PAS(0.006)S(0.709)T(0.211)T(0.008)AR 105.36 0.0010041 26882000.0 26466.0 24517.0 29467.0 44034.0 36471.0 28800.0 29056.0 39356.0 29170.0 28006.0 True False 34881.63747300207 32441.640793934133 29076.24832660424 33882.641618518224 31407.631185284692 26999.131447210253 31641.927711069522 33274.43451091028 30711.86664826474 27025.51846436297 1.2906926288573712 1.2004077123150514 1.0758812403523526 1.2537277189778009 1.1621472212161321 0.9990236258672517 1.1708166765715875 1.2312227998433187 1.1364024963577573 1.0 14.72203467480042 -14.522878745280336 0.08425379653650568 0.5402394661657033 1.2991246127674712 0.32120016289338016 0.07868238375049148 341.33079809278314 2.012950931421933 29.86139399492291 2.4524539118523103 3.0000000000000132e-15 14.522878745280336 0.7588851466017679 SAMPFTASPASS(ph)TTAR ddPTM_PC-9_Lapatinib_30min_R1 1 SAMPFTASPASSTTAR 16 0 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 1 SAMPFT(0.018)AS(0.024)PAS(0.007)S(0.591)T(0.18)T(0.18)AR 80.737 0.0068797 28869000.0 138450.0 154380.0 174300.0 124080.0 145220.0 127910.0 131890.0 111930.0 132920.0 95166.0 True False 136475.67761137956 154022.54259507888 159969.72681745733 133205.25711874577 136678.44511350497 122439.58747277335 138718.61885727374 117130.67642055446 117949.14989034808 111615.31629927557 1.2227325257534154 1.3799409230010715 1.4332237915137782 1.1934317039570161 1.2245491895308285 1.096978367596742 1.242827807657918 1.0494140078991532 1.0567469931643567 1.0 16.768175487561244 -6.943947340007939 0.5041599988796053 1.0074113696602842 1.3616500891538954 0.6642107915181545 0.07829898882093536 0.6140067530546973 0.33463963893209453 0.07437778534156801 0.08419682117379619 1.1377652361739311e-07 6.943947340007939 0.3542387194936112 SANAFLTPS(ph)YTWTPLKTEVDESQATK ddPTM_PC-9_AZD4547_30min_R2 1 SANAFLTPSYTWTPLKTEVDESQATK 26 1 Q15398-1;Q15398;Q15398-3 Q15398-1 DLGAP5 Disks large-associated protein 5 1 SANAFLT(0.015)PS(0.397)Y(0.348)T(0.104)WT(0.133)PLKT(0.002)EVDES(0.001)QAT(0.001)K 56.562 0.019079 0.0 8618.0 7771.1 9243.2 12941.0 10374.0 11396.0 7926.7 18230.0 9337.1 11082.0 True False 11358.34473446429 10282.956102856855 9120.629128600413 9957.652386456932 8933.749168274611 10683.406318486388 8632.16094394738 15412.972383725335 9830.640043932557 10694.022553098283 1.0621208883811022 0.9615611012413348 0.8528716938190836 0.931141891371081 0.8353965146338986 0.9990072739645739 0.8071949447541105 1.4412698596058107 0.9192649440489925 1.0 13.38451700396536 SANAFLTPS(ph)YTWTPLKTEVDESQATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SANAFLTPSYTWTPLKTEVDESQATK 26 1 Q15398-1;Q15398;Q15398-3 Q15398-1 DLGAP5 Disks large-associated protein 5 1 SANAFLT(0.015)PS(0.306)Y(0.267)T(0.233)WT(0.179)PLKTEVDESQATK 69.248 0.0027775 0.0 13552.0 12397.0 11641.0 14855.0 13285.0 10164.0 10719.0 8437.8 9574.0 9532.8 True False 15846.085935799205 13627.692231081226 11918.565588738342 14022.722510559799 10681.899617170453 9630.981947300603 9703.618721160394 8216.316690588095 9714.001637771491 11261.021178396722 1.40716243089912 1.2101648700585657 1.058391188501009 1.245244306747345 0.9485729089705236 0.8552494302893945 0.8616997133240395 0.7296244772499296 0.8626217359760363 1.0 13.459050040200966 -6.020809229084505 0.7880729019680561 0.8257718479682131 1.3325053183253956 0.7472546658671539 0.10117534886779725 0.3785131126893955 0.4715585733869893 0.05212748431268855 0.12388391259432822 9.532147871738509e-07 6.020809229084505 0.5067334703571825 SANAFLTPSYTWT(ph)PLKTEVDESQATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SANAFLTPSYTWTPLKTEVDESQATK 26 1 Q15398-1;Q15398;Q15398-3 Q15398-1 DLGAP5 Disks large-associated protein 5 1 SANAFLT(0.013)PS(0.305)Y(0.254)T(0.099)WT(0.326)PLKT(0.003)EVDES(0.001)QATK 83.601 3.2193000000000002e-06 4311700.0 17305.0 14521.0 14649.0 16822.0 17907.0 11748.0 15291.0 14783.0 11732.0 9261.1 True False 20234.394710670393 15962.548914054252 14998.287716641875 15879.51787765985 14398.251896475072 11131.914198827972 13842.525782746841 14394.961913883219 11903.558305236587 10940.064119172737 1.849568200903787 1.459090983395562 1.3709506227076858 1.4515013536191799 1.3161030629831296 1.0175364675714298 1.2653057269095405 1.3158023350755035 1.0880702503722353 1.0 13.417333573268717 -1.5228787452803403 0.34251544901626646 1.1217799921633624 8.559931536561157 0.7730838153267343 0.11372280558817578 30.584655944909382 0.43274355249034857 0.1022243363895504 145.8446123739348 0.02999999999999981 1.5228787452803403 7.438151544397795 SANMDHWQQR ddPTM_PC-9_Lapatinib_30min_R1 1 SANMDHWQQR 10 0 H7C0X7;Q9NZL9-3;Q9NZL9-4;Q9NZL9-2;Q9NZL9 H7C0X7 MAT2B Methionine adenosyltransferase 2 subunit beta 0 72.289 0.021 1352500.0 5125.0 5949.0 8000.5 5174.7 6828.5 8090.3 6096.2 6242.9 8780.1 5675.1 False True 5051.916560190106 5935.2254560054735 7342.729772823089 5555.264700293157 6426.8610553475355 7744.296728410427 6411.831407064316 6532.967924826936 7791.192679448128 6656.033473404578 0.7589980700031002 0.8917060708484674 1.1031689972958119 0.8346209078560455 0.9655692209222289 1.163500267742674 0.9633111721393806 0.9815106776326511 1.1705458980306047 1.0 12.7004469735187 -3.8846744072568664 0.7377744452208447 1.0309434569163618 7.338239062167369e-27 0.4185912013151867 0.09755970962896005 9.538263404073373 1.4862153555586268 0.038147341304614356 11.095930821028515 0.00013041441354165952 3.8846744072568664 -1.0309434569163618 SANPPHTIQASEEQS(ph)STPAPVKK ddPTM_PC-9_AZD4547_30min_R2 1 SANPPHTIQASEEQSSTPAPVKK 23 1 E9PS53;E9PHZ9;B7Z524;H0YDX7;J3QT46;Q9Y450-4;Q9Y450 E9PS53 HBS1L HBS1-like protein 1 SANPPHT(0.001)IQAS(0.095)EEQS(0.324)S(0.324)T(0.256)PAPVKK 44.632 0.022769 6835900.0 13771.0 14982.0 29003.0 41297.0 33321.0 41324.0 24584.0 46323.0 34589.0 38431.0 True False 18149.891545405866 19824.638511021796 28618.401269776463 31776.61468228976 28694.954312326827 38740.00374737903 26771.928374481464 39164.844746643415 36417.30392515694 37085.54238748601 0.48940612370631764 0.5345651495098892 0.7716861997259971 0.8568464322369551 0.7737504284691149 1.0446120308180067 0.7218966381765868 1.056067734898736 0.9819811597914081 1.0 15.178569248578071 -4.596586812005226 0.47386972272643296 0.9777763048213012 8.560026037369438e-16 0.7427629342432784 0.09768318257740373 2.7973172051101223 0.42682559937576137 0.06337144751123115 1.5914614197830912 2.5317055169450725e-05 4.596586812005226 -0.9777763048213003 down SANPPHTIQASEEQSS(ph)TPAPVKK ddPTM_PC-9_AZD4547_30min_R2 1 SANPPHTIQASEEQSSTPAPVKK 23 1 E9PS53;E9PHZ9;B7Z524;H0YDX7;J3QT46;Q9Y450-4;Q9Y450 E9PS53 HBS1L HBS1-like protein 1 SANPPHTIQAS(0.034)EEQS(0.142)S(0.632)T(0.192)PAPVKK 56.708 0.003061 8384400.0 18851.0 12063.0 29417.0 51102.0 41828.0 43089.0 35466.0 46604.0 36121.0 45522.0 True False 24845.22587484176 15962.128845177942 29026.911359273643 39321.223418029644 36020.90420383561 40394.638018362595 38622.405293254145 39402.422653381 38030.282317517 43928.288635818426 0.5655860186318152 0.36336787388896086 0.6607794717412588 0.8951230434678884 0.81999334193194 0.9195586550900927 0.8792148861852553 0.8969714932453092 0.8657355771995113 1.0 15.422862675367316 -5.57166946972598 3.123274794861599 0.8900324085177606 0.4660741660488082 0.8807709764437894 0.064315426084555 0.06925952401616653 1.3709992684468324 0.0167130613715659 0.033707639262494406 2.681208146520929e-06 5.57166946972598 -0.42395824246895236 SANPPHTIQASEEQSS(ph)TPAPVKK ddPTM_PC-9_Lapatinib_30min_R1 2 SANPPHTIQASEEQSSTPAPVKK 23 1 E9PS53;E9PHZ9;B7Z524;H0YDX7;J3QT46;Q9Y450-4;Q9Y450 E9PS53 HBS1L HBS1-like protein 1 SANPPHTIQAS(0.002)EEQS(0.045)S(0.477)T(0.477)PAPVKK;SANPPHTIQAS(0.003)EEQS(0.233)S(0.708)T(0.056)PAPVKK 72.383 0.00025669999999999995 17007200.0 104749.0 70415.0 125924.0 86557.0 89367.0 81639.0 57930.0 65558.0 98093.0 43450.0 True False 103255.26005138602 70251.95839378482 115571.01480069701 92922.69052568733 84110.60876228214 78147.49027980413 60929.331946333055 68604.06401124531 87044.73337491664 50960.27460651428 2.0261912018462094 1.3785631835038126 2.267864835758234 1.8234338657548947 1.6505132558985511 1.5334982176452892 1.1956240898777344 1.3462263408305029 1.7080899592285492 1.0 15.637085431327119 -6.700099823883513 1.9043232813941828 1.3449053725092701 1.862001285873779 0.4645001001802882 0.26714708292538847 0.3246334438403619 2.4248273029024636 0.104536435650748 0.10007272545646285 1.994803750670932e-07 6.700099823883513 0.517095913364509 SANPTRPSS(ph)PVTSHISK ddPTM_PC-9_AZD4547_30min_R2 1 SANPTRPSSPVTSHISK 17 1 Q92560;F8W6N3;H0Y8E8 Q92560 BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1;Ubiquitin carboxyl-terminal hydrolase 1 SANPTRPS(0.242)S(0.736)PVT(0.018)S(0.004)HISK 86.189 0.0014662000000000002 11886000.0 5852.8 2263.1 9258.4 32171.0 19126.0 10974.0 7439.3 17256.0 9873.3 15015.0 True False 7713.868654197326 2994.60281766743 9135.627566668902 24754.472986995286 16470.68503879124 10287.79404519741 8101.383288166288 14589.481703431946 10395.18248125856 14489.329420210312 0.53238272320855 0.2066764258593248 0.6305072720567836 1.7084622944983727 1.1367458466240163 0.7100255468584745 0.5591275519532427 1.0069121406738077 0.7174371000744129 1.0 13.822703206706278 -5.5283780187355305 24.9997484703785 0.9718427777786035 0.38179500322842996 0.3978741435209213 0.3047575381083612 144.9627931521306 659000.2676461617 0.08911980653828086 0.15497250402699733 2.9622518628801406e-06 5.5283780187355305 -0.5900477745501735 SANPTRPSS(ph)PVTSHISK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SANPTRPSSPVTSHISK 17 1 Q92560;F8W6N3;H0Y8E8 Q92560 BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1;Ubiquitin carboxyl-terminal hydrolase 1 S(0.034)ANPT(0.092)RPS(0.226)S(0.626)PVT(0.016)S(0.005)HIS(0.001)K 48.244 0.045101999999999996 5549800.0 0.0 5908.5 11498.0 13332.0 19426.0 17410.0 14191.0 11977.0 16128.0 10711.0 True False 0.0 6495.056832083844 11772.15592640783 12585.051262927178 15619.614750707819 16496.988951446638 12846.7257460572 11662.616440680466 16363.841488821652 12652.819511770658 0.0 0.513328813869638 0.9303978386363952 0.9946440199529886 1.2344770061864245 1.3038191950892706 1.015325140306171 0.9217405203505016 1.2932960494377326 1.0 13.627171285607357 -5.10027449008703 1.6379884764937087 1.116384603079381 1.7913092735946928e-13 0.8820463615769406 0.1293515821123636 0.18772148942409556 0.7463696193755672 0.038447532347570604 0.2743871258650675 7.938263486844277e-06 5.10027449008703 -1.1163846030792017 down SANT(ph)SPESSSR ddPTM_PC-9_AZD4547_30min_R2 1 SANTSPESSSR 11 0 P20749;H7C0A2 P20749 BCL3 B-cell lymphoma 3 protein 1 S(0.002)ANT(0.969)S(0.015)PES(0.01)S(0.003)SR 84.81700000000001 0.028856 7141400.0 7447.6 8176.8 10268.0 10511.0 9053.2 11354.0 9112.0 12806.0 8692.5 10285.0 True False 9815.781880296614 10819.79069396096 10131.83961100798 8087.851343331176 7796.319449607072 10644.032585125871 9922.950347717013 10827.126952604867 9151.96780390953 9924.925280510352 0.9890031010683714 1.0901634408480498 1.0208479484378534 0.8149029957145723 0.78552928402562 1.072454681953892 0.9998010128300697 1.090902616049531 0.9221195671751118 1.0 13.27684052567406 -9.286755436827649 14.798166086166662 0.9999999997506754 0.9774051745881198 0.00478108054882842 0.10170234935954442 0.0 0.0 0.10676921531774432 0.02589533837172794 5.167072594352192e-10 9.286755436827649 -0.02259482516255562 SANT(ph)SPESSSR ddPTM_PC-9_Lapatinib_30min_R1 1 SANTSPESSSR 11 0 P20749;H7C0A2 P20749 BCL3 B-cell lymphoma 3 protein 1 SANT(0.664)S(0.305)PES(0.029)S(0.001)SR 101.38 0.0091874 7732500.0 8328.1 10629.0 11933.0 8683.6 14330.0 10632.0 9749.8 14228.0 14709.0 11437.0 True False 8209.339766813504 10604.389203543811 10951.914802712083 9322.22091164042 13487.13757386398 10177.294144402511 10254.596937862212 14889.084821867655 13052.317527363297 13413.870211155436 0.6120038167647048 0.7905540337437317 0.816461962901959 0.6949687722405231 1.005462059909273 0.758714225215831 0.7644771252769493 1.1099768066553515 0.973046355891273 1.0 13.711437927669866 -5.833094558500671 0.2685158617816635 1.0488105478976886 0.5301125972183961 0.4903339681799318 0.10834346048394557 4.683157681485703 0.45368059446984804 0.16292654442174861 0.7835890434209907 1.4686064846184573e-06 5.833094558500671 -0.5186979506792925 SANTS(ph)PESSSR ddPTM_PC-9_AZD4547_30min_R2 1 SANTSPESSSR 11 0 P20749;H7C0A2 P20749 BCL3 B-cell lymphoma 3 protein 1 S(0.001)ANT(0.241)S(0.757)PES(0.001)SSR 79.744 0.016939 10153000.0 11985.0 13382.0 14124.0 21189.0 16961.0 14544.0 12862.0 14516.0 15285.0 13595.0 True False 15795.98069651362 17707.46980072712 13936.706531542346 16304.203416786635 14606.257918170984 13634.561380841182 14006.69308300442 12272.885744495732 16092.933895054033 13119.043187995941 1.2040497519641602 1.3497531448733728 1.0623264465120883 1.2427890649605566 1.1133630485747512 1.0392954109120507 1.0676611763745611 0.9355015886925007 1.2266850306415054 1.0 13.679374883173887 -5.9925660637873515 0.8034297122320625 1.0450893504300902 1.2685453236983983 0.3805370691137323 0.09549101947660323 0.7633451281726289 0.9800860278903426 0.04569915542392372 0.11187206318020304 1.0172646106691767e-06 5.9925660637873515 0.22345597326830813 SANTS(ph)PESSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SANTSPESSSR 11 0 P20749;H7C0A2 P20749 BCL3 B-cell lymphoma 3 protein 1 S(0.001)ANT(0.23)S(0.769)PESSSR;SANT(0.398)S(0.602)PES(0.001)SSR 139.74 0.00011428 16740200.0 26124.6 38441.0 40451.0 30247.0 44465.0 33776.0 34699.0 28925.7 30569.2 29624.1 True False 30546.978795630162 42257.16843228146 41415.505251271796 28552.358652097104 35752.40244467326 32004.727100750228 31412.0595209949 28166.43102431252 31016.2167187554 34994.71482575345 0.8729026353759543 1.2075300125373045 1.1834788612363012 0.8159048814732658 1.0216514871657765 0.9145588772507207 0.8976229604213837 0.8048767125138613 0.8863114579785009 1.0 15.094849431023276 -5.760892775790495 24.99999962128795 0.9025620462958907 1.099926460301889 0.38329565992477577 0.10547993020822735 13.912370341027168 636244.3188209978 0.028925940052808585 0.046457522171789646 1.734232114440247e-06 5.760892775790495 0.19736441400599836 SANTS(ph)PESSSR ddPTM_PC-9_Lapatinib_30min_R1 1 SANTSPESSSR 11 0 P20749;H7C0A2 P20749 BCL3 B-cell lymphoma 3 protein 1 SANT(0.08)S(0.92)PESSSR 144.51 0.00017885 8562400.0 20697.0 26686.0 27340.0 23790.0 27104.0 27561.0 26811.0 29198.0 31188.0 26109.0 True False 20401.856984635055 26624.210206582957 25092.21073545196 25539.595961113548 25509.79600851425 26382.280277828988 28199.142392769463 30554.645672539515 27675.279015800294 30621.905861944313 0.666250398541969 0.869449809120812 0.8194202819568969 0.8340302552119443 0.8330570972140833 0.8615492581281767 0.9208813625089951 0.9978035270009635 0.903773891167043 1.0 14.902276456378303 -1.886658874672981 0.1565137587311064 1.0334649594416097 1.0985884976990267e-18 0.7239437364562575 0.04808640422612711 32.18457474068334 0.36303552554989976 0.15763853771988837 7.459237200330951 0.012981985667671322 1.886658874672981 -1.0334649594416097 SAPAS(ph)PTHPGLMS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 SAPASPTHPGLMSPR 15 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 2 S(0.137)APAS(0.841)PT(0.023)HPGLMS(0.999)PR 100.58 0.022300999999999998 7524600.0 9414.9 9835.2 12410.0 8729.5 15772.0 17893.0 17795.0 17112.0 23032.0 18965.0 True False 9280.641799518793 9812.427198672885 11389.69770398532 9371.496550758327 14844.321968945054 17127.758100620224 18716.338028396276 17907.085990427295 20437.893622287836 22243.074980725956 0.41723735623607094 0.44114526463519715 0.5120558966714228 0.4213219871298778 0.6673682475021074 0.7700265415398613 0.8414456204735332 0.8050634188817923 0.918842994504926 1.0 14.441068625919593 -6.716938907937017 0.7307530643531333 0.9348951818902544 0.40591475626530854 0.9385018872335313 0.05146146117997243 0.1622939036673962 0.1913172734491916 0.03744933329589082 0.039182522948572274 1.9189386581597995e-07 6.716938907937017 -0.528980425624946 down SAPAS(ph)PTHPGLMSPR ddPTM_PC-9_AZD4547_30min_R2 5 SAPASPTHPGLMSPR 15 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 S(0.177)APAS(0.814)PT(0.009)HPGLMSPR;S(0.001)APAS(0.997)PT(0.001)HPGLMS(0.001)PR;SAPAS(0.99)PT(0.01)HPGLMSPR;S(0.003)APAS(0.952)PT(0.045)HPGLMSPR;S(0.055)APAS(0.765)PT(0.18)HPGLMSPR 169.98 0.00016281 29804000.0 43976.5 39525.3 88305.0 118007.0 111768.0 100761.4 66033.5 99003.2 68793.1 89038.1 True False 57960.112231975945 52301.08026563144 87134.018002538 90802.30933997553 96250.94245611288 94460.77372933777 71910.35357616014 83704.53030720988 72429.36282210278 85920.9032200884 0.6745752204618912 0.6087119467501524 1.0141189714840657 1.0568127887038536 1.1202273119681232 1.0993922338941702 0.8369366577997917 0.974204497045367 0.8429772047038807 1.0 16.390721538891086 -5.263005068260599 24.99999707590272 0.997199382040687 0.641643559188691 0.7076279602268005 0.09032912360212757 72.37278203838103 1155628.455622762 0.025490576735225028 0.058052442708468446 5.457514920789092e-06 5.263005068260599 -0.35555582285199605 SAPAS(ph)PTHPGLMSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SAPASPTHPGLMSPR 15 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 S(0.152)APAS(0.808)PT(0.039)HPGLMSPR;S(0.015)APAS(0.59)PT(0.395)HPGLMSPR 77.795 0.0087058 28943800.0 20258.6 23555.3 42278.2 35812.0 54268.0 56728.0 56995.0 53219.0 54171.0 46367.0 True False 23687.9808544113 25893.71451244558 43286.272628966384 33805.56974407052 43634.57496609758 53753.08381606345 51596.02099193359 51822.057640191546 54963.148393536576 54772.97005902997 0.43247574175514436 0.47274621924900884 0.7902852918568386 0.6171943881742683 0.7966443104887628 0.9813797527892433 0.9419978674942674 0.94612465937746 1.0034721201771906 1.0 15.741176492036727 -5.198297924584827 0.43625894847502883 1.0194067406132001 0.12375157788047171 0.8835717063622056 0.07087742788767465 1.180119232846759 0.229631911673531 0.0573662758114293 0.5290706021640931 6.334350278345385e-06 5.198297924584827 -0.8956551627327284 down SAPAS(ph)PTHPGLMSPR ddPTM_PC-9_Lapatinib_30min_R1 6 SAPASPTHPGLMSPR 15 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 SAPAS(0.956)PT(0.044)HPGLMSPR;S(0.001)APAS(0.99)PT(0.009)HPGLMSPR;S(0.192)APAS(0.805)PT(0.003)HPGLMSPR;S(0.001)APAS(0.954)PT(0.045)HPGLMSPR;S(0.001)APAS(0.625)PT(0.365)HPGLMS(0.009)PR;SAPAS(0.449)PT(0.449)HPGLMS(0.101)PR 166.79 0.00024565 59935300.0 76943.8 56698.399999999994 91750.8 71553.7 111098.6 147035.7 99659.2 123359.0 180803.0 114091.9 True False 75846.56730223521 56567.118338339315 84207.40339233016 76815.99779414594 104563.99877625145 140747.32586795746 104819.06573978942 129090.70948416989 160439.0622000045 133812.53289709915 0.5668121338123139 0.42273408262766393 0.6292938454209295 0.5740568251048418 0.7814215642764971 1.0518246895168715 0.7833277158006904 0.9647131452435751 1.1989838225645197 1.0 17.02985371972654 -6.418887951557925 0.8856907237928819 1.0269442212276798 0.4836959892599621 0.7921972833251724 0.10856428429406405 0.26855705263068275 0.4595443554683263 0.05915437010430592 0.08036944829366695 3.811641514686986e-07 6.418887951557925 -0.5432482319677177 SAPASPTHPGLMS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 SAPASPTHPGLMSPR 15 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 SAPASPTHPGLMS(1)PR;SAPAS(0.001)PT(0.004)HPGLMS(0.996)PR 61.657 0.031997000000000005 7178200.0 9125.5 8077.1 23010.0 49770.0 41113.0 32071.0 19013.1 40545.0 20384.5 35308.0 True False 12027.219177808522 10687.864618700723 22704.872365533072 38296.29543883481 35405.16961203722 30065.59530012083 20705.229066744785 34279.701881412184 21461.983054218446 34071.87766691877 0.35299549075001657 0.31368581218750485 0.6663816003183703 1.1239854701643763 1.0391317425518047 0.8824167424536236 0.6076926334719734 1.0060995820813008 0.6299031495718364 1.0 15.056293834647589 -5.435382965809708 3.709340523231344 0.89272186500188 0.3382478151360866 0.6622808794315986 0.15991669909332804 0.1407431089843167 3.5710532892082107 0.044464713549770496 0.09863769344661238 3.6695856954729665e-06 5.435382965809708 -0.5544740498657934 SAPGS(ph)TPVR ddPTM_PC-9_Lapatinib_30min_R1 1 SAPGSTPVR 9 0 F5H1D6;Q07864;A0A087WW42;A0A087WX51 F5H1D6 POLE DNA polymerase;DNA polymerase epsilon catalytic subunit A 1 S(0.009)APGS(0.752)T(0.239)PVR 91.867 0.0074698 13026000.0 79997.0 72152.0 88431.0 69767.0 67882.0 73760.0 64361.0 71504.0 92077.0 56306.0 True False 78856.22811034681 71984.93647700573 81160.54453353149 74897.89791588957 63889.314221146946 70605.45674295792 67693.29765920831 74826.33687818577 81706.31864620504 66038.41707697105 1.1940962791163812 1.0900463648773369 1.2289898535716695 1.134156468780776 0.9674567781762665 1.0691573158191203 1.0250593617395223 1.1330728413882478 1.2372543477378066 1.0 16.011017919204416 -6.0111354358473355 24.839973400923146 1.0738593023097738 1.1660491893164349 0.25297862670391913 0.07740091499639214 765.381414767451 1707352.3938315453 0.023041689177240404 0.031722297457885205 9.746856321047665e-07 6.0111354358473355 0.09218988700666109 SAPGS(ph)TPVRR ddPTM_PC-9_Lapatinib_30min_R1 1 SAPGSTPVRR 10 1 F5H1D6;Q07864;A0A087WW42;A0A087WX51 F5H1D6 POLE DNA polymerase;DNA polymerase epsilon catalytic subunit A 1 SAPGS(0.865)T(0.135)PVRR 100.69 0.005717 1704900.0 11263.0 10709.0 14972.0 10556.0 11494.0 13691.0 10546.0 9122.8 13514.0 8520.3 True False 11102.387554618757 10684.203968458994 13741.059953591326 11332.323453783722 10817.945518073453 13105.467845279802 11092.020278025695 9546.67859241877 11991.911011271175 9993.022502413889 1.1110139651878992 1.0691664074486118 1.3750654469428114 1.1340236100785637 1.0825499007392707 1.3114618567219356 1.1099765136470308 0.9553344436193052 1.200028420667965 1.0 13.286705388078023 -7.519115377753816 24.903579533911035 1.0531399422979346 1.1805036397215494 0.22294139906966015 0.10860500349417097 234.6435747420355 1552756.5800999608 0.04915120598201256 0.02920060390998583 3.02610938360983e-08 7.519115377753816 0.12736369742361475 SAPGST(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 1 SAPGSTPVR 9 0 F5H1D6;Q07864;A0A087WW42;A0A087WX51 F5H1D6 POLE DNA polymerase;DNA polymerase epsilon catalytic subunit A 1 S(0.001)APGS(0.262)T(0.737)PVR 91.63600000000001 0.018699 13016000.0 43030.0 42825.0 64076.0 75528.0 65590.0 68428.0 53203.0 72020.0 50138.0 70478.0 True False 56712.64492039894 56667.34376148099 63226.31037348535 58116.1864959677 56483.96066581178 64149.18634269801 57937.96393213216 60890.96385495876 52788.192321244336 68010.58667183352 0.8338796604424293 0.833213570630022 0.9296539475327071 0.8545167648147407 0.8305171801907794 0.9432235403619199 0.8518962527362977 0.8953159623335033 0.7761761058753884 1.0 16.053471716355837 -11.83821937536129 2.4929738366178027 1.8298335956817267 0.8642210640894443 0.4347305276500725 0.04744022914831019 5256786.451704427 1773701.246776461 25759534.65057246 0.011814301551903824 1.4513782970391068e-12 11.83821937536129 -0.9656125315922823 SAPGST(ph)PVRR ddPTM_PC-9_AZD4547_30min_R2 1 SAPGSTPVRR 10 1 F5H1D6;Q07864;A0A087WW42;A0A087WX51 F5H1D6 POLE DNA polymerase;DNA polymerase epsilon catalytic subunit A 1 SAPGS(0.021)T(0.979)PVRR 75.819 0.020361 5710200.0 3313.9 3939.2 5153.0 7769.4 5443.7 4712.9 5261.6 6841.7 4460.2 5390.9 True False 4367.651266597955 5212.469364745495 5084.667853089615 5978.284866033417 4687.93622010184 4418.201617970736 5729.87220693019 5784.472471625546 4695.957066321231 5202.166231862255 0.8395831797621042 1.001980546646152 0.9774135670534738 1.1491914328722497 0.9011507920275873 0.8493003531702067 1.1014396602391978 1.1119353388203512 0.9026926201549287 1.0 12.344896785067865 -4.761416914694158 10.686591109160377 1.0023957371987922 0.8391233940951677 0.20739309968896502 0.09360389769045536 0.11442153574996754 380.7849588254203 0.023891036482181965 0.1345596193824987 1.7321403765385593e-05 4.761416914694158 -0.16327234310362448 SAPGST(ph)PVRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SAPGSTPVRR 10 1 F5H1D6;Q07864;A0A087WW42;A0A087WX51 F5H1D6 POLE DNA polymerase;DNA polymerase epsilon catalytic subunit A 1 SAPGS(0.045)T(0.955)PVRR;S(0.006)APGS(0.186)T(0.807)PVRR 82.505 0.012584 8955300.0 12429.2 13290.5 14228.0 15381.6 17084.5 14732.2 17316.6 17504.8 16045.2 13480.5 True False 14533.218072110065 14609.89300614545 14567.249479990473 14519.81881982003 13736.914867109423 13959.617497444122 15676.246286672811 17045.317547868697 16279.830695463872 15924.407938420722 0.9126378907341264 0.917452822273929 0.9147749502726665 0.9117964621333363 0.8626326906613873 0.876617677179937 0.9844162713799128 1.0703894056082024 1.0223193702659188 1.0 13.958952114342935 -7.449670516330128 4.055659643235136 1.0343668144653841 0.900267207954422 0.8657596166288936 0.023605489573811617 0.07875583349934738 2.465504900555428 0.011324688250335349 0.007151705706227174 3.550826755809621e-08 7.449670516330128 -0.1340996065109621 SAPGTS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 SAPGTSPR 8 0 Q03111 Q03111 MLLT1 Protein ENL 1 SAPGT(0.09)S(0.909)PR 69.176 0.041582 20227000.0 227290.0 159450.0 186080.0 263970.0 225090.0 210590.0 168930.0 189630.0 266310.0 283710.0 True False 299563.49207430874 210989.094285304 183612.457617488 203115.79479584526 193840.1388362189 197421.77400930593 183964.44273922723 160327.0407638965 280386.6029173598 273777.3992546034 1.0941863458777514 0.770659283270828 0.6706633130324057 0.7419012502451112 0.7080209665369577 0.7211032559547056 0.6719489747513699 0.5856109423217873 1.0241407935087075 1.0 18.062643829253574 -8.28194168698228 24.343422551308837 1.0120705664510057 0.7392193361161874 0.4125806298110265 0.12704760897668468 653.1255173673978 775478.6738367038 0.123337653202316 0.03201847654158085 5.2246633620268064e-09 8.28194168698228 -0.2728512303348183 SAPGTS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SAPGTSPR 8 0 Q03111 Q03111 MLLT1 Protein ENL 1 S(0.003)APGT(0.214)S(0.783)PR;SAPGT(0.081)S(0.919)PR 83.78299999999999 0.014566999999999998 143654000.0 285781.0 449490.0 448790.0 331169.0 672480.0 675310.0 353265.0 451470.0 601890.0 475390.0 True False 334158.07886796264 494112.39662407804 459490.85564555187 312614.67459438386 540712.3714380723 639895.5547846882 319801.1817828824 439619.3908720047 610691.5025859915 561574.4438148311 0.5950379020063548 0.8798698054482739 0.81821895691012 0.5566753936855838 0.9628507447115281 1.1394670142711871 0.5694724631883908 0.7828336843208648 1.0874631303331814 1.0 19.09911775726495 -1.789793314197913 0.10483861258296066 1.0888011415014018 4.122914176478463e-17 0.1915590519418564 0.1821495751000677 230.53409234390278 1.8080106080973193 2.1308659999132846 36.00597497763091 0.01622582119365753 1.789793314197913 -1.0888011415014018 SAPGTS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 SAPGTSPR 8 0 Q03111 Q03111 MLLT1 Protein ENL 1 SAPGT(0.091)S(0.909)PR 73.233 0.030511 24188000.0 189070.0 230350.0 218030.0 210130.0 273070.0 194850.0 262440.0 275340.0 279720.0 184350.0 True False 186373.82712880804 229816.638727662 200104.4150201384 225583.66117313143 257008.55947627642 186516.71971753478 276027.8590712176 288133.30157808884 248214.9880178168 216214.65186906597 0.861985187024565 1.0629096443789252 0.925489615483212 1.0433319815427637 1.18867318775378 0.8626460700289845 1.2766380848156995 1.3326261614896244 1.1480026255025926 1.0 17.722104765606538 -6.547784097130684 0.8154505308044331 1.1921763590874432 0.953798893086271 0.2649761351744523 0.1340981879371491 0.8150656059978681 1.2007589468274433 0.08221518485997965 0.09912495162881986 2.832799929027521e-07 6.547784097130684 -0.23837746600117227 SAPS(ph)SPAPR ddPTM_PC-9_AZD4547_30min_R2 1 SAPSSPAPR 9 0 E9PAK5;O75064 E9PAK5 DENND4B DENN domain-containing protein 4B 1 S(0.001)APS(0.5)S(0.5)PAPR 87.806 0.010606 9002700.0 69562.0 53953.0 73065.0 81288.0 77165.0 62279.0 70623.0 84326.0 68952.0 64887.0 True False 91681.26902051552 71392.25214158055 72096.11036017709 62548.30748708058 66451.97171485538 58384.68428475028 76908.31018512043 71295.35431870683 72596.661951702 62615.325880065655 1.4641985445563794 1.1401721725177372 1.151413161983235 0.9989296806805184 1.0612732710540944 0.9324344074577076 1.2282665482318462 1.1386246628384085 1.1594072366684596 1.0 15.934228197490546 -4.469061867533303 1.7178270165376923 1.0832797894719635 1.940143663751176 0.6415675835882668 0.08479841137855869 1.6311963469484627 2.410139022640864 0.024020609189640958 2.9839068226802388 3.395768946298542e-05 4.469061867533303 0.8568638742792125 SAPS(ph)SPAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SAPSSPAPR 9 0 E9PAK5;O75064 E9PAK5 DENND4B DENN domain-containing protein 4B 1 S(0.002)APS(0.499)S(0.499)PAPR;S(0.002)APS(0.499)S(0.499)PAPR 77.533 0.02292 15696700.0 112411.0 126163.0 109711.0 122832.0 140646.0 117504.0 129414.0 116339.0 110658.0 105291.0 True False 131439.96208154707 138687.62885778 112326.92632128474 115950.1212667172 113087.42593575889 111341.88338603023 117154.96904377738 113285.2245213596 112276.16390563191 124379.4248169023 1.056766119276066 1.1150367439143625 0.9030989368751309 0.9322291161693841 0.9092132891130004 0.8951792754302851 0.9419159898531452 0.9108035729231393 0.9026908113694248 1.0 16.924388325100942 -5.2639032741834075 24.999499614575846 0.9205262188720424 1.0859014400280056 0.8047838233705777 0.031772772771257306 70.61829893338096 716525.4052967457 0.007576137283721958 0.01705178115614667 5.4462393766504e-06 5.2639032741834075 0.16537522115596315 SAPS(ph)SPAPR ddPTM_PC-9_Lapatinib_30min_R1 2 SAPSSPAPR 9 0 E9PAK5;O75064 E9PAK5 DENND4B DENN domain-containing protein 4B 1 S(0.012)APS(0.494)S(0.494)PAPR;S(0.006)APS(0.497)S(0.497)PAPR 73.885 0.028388 16244300.0 153351.0 150153.0 152700.0 144398.0 142954.0 150386.0 142295.0 155396.0 153227.0 118835.0 True False 151164.18661887108 149805.329953873 140145.59543904607 155017.51061760733 134545.7267783777 143954.34134688813 149662.3388452178 162616.26546098856 135968.96170815793 139375.47141231585 1.0845824239164763 1.074832812659714 1.0055255348658299 1.1122294981088707 0.9653472409097704 1.0328527673354129 1.0738068709555801 1.1667495278270252 0.9755587574367344 1.0 17.088617159132966 -11.168462867700118 15.263232179488224 0.9999997817458155 1.0560529574914248 0.07134913843239976 0.05889776038291897 4.2720256030873137e-07 9.894281968681807e-09 0.05568492065387264 0.013505524510743203 6.784801282594459e-12 11.168462867700118 0.05605317574560931 SAPSGPVR ddPTM_PC-9_Lapatinib_30min_R1 3 SAPSGPVR 8 0 P38159;P38159-2;H3BUY5;H0Y6E7;H3BT71 P38159 RBMX RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed 0 ;; 99.375 0.024045 7895500.0 32239.7 30735.1 34065.2 33903.1 33524.9 32339.7 32184.6 29783.0 29406.9 27509.1 False True 31779.9559659631 30663.934764308928 31264.490751474703 36396.44707142617 31553.03129448935 30956.60641852276 33850.96110754275 31166.826908187006 26094.785253614806 32264.01128142832 0.9849970510100878 0.9504067704674892 0.9690205746199649 1.1280818976274207 0.9779636827938929 0.9594779194842978 1.049186377114488 0.9659935535085536 0.808789242788152 1.0 14.97763819485845 -8.010995684689904 24.6224311900234 0.8987268636522356 1.0020547764429786 0.26133570824120733 0.06549210440911458 521.6590619835308 1168133.7031320387 0.03882518210458186 0.016619553476186433 9.749993256220355e-09 8.010995684689904 0.10332791279074294 SAPSQASSFT(ph)PPASGGPR ddPTM_PC-9_AZD4547_30min_R2 1 SAPSQASSFTPPASGGPR 18 0 G5EA31;P53992;A0A0U1RR49 G5EA31;A0A0U1RR49 SEC24C Protein transport protein Sec24C 1 SAPSQASS(0.002)FT(0.76)PPAS(0.238)GGPR 139.12 2.1553e-08 0.0 2180.4 2047.2 4102.3 5777.1 4971.5 3559.7 1568.2 5827.0 1593.5 1582.4 True False 2873.7218448626063 2708.91736482204 4047.9008216047973 4445.278850305254 4281.293039336538 3337.111396272025 1707.7667619940537 4926.571041139199 1677.7291568052735 1527.0006576450742 1.8819388390404708 1.7740119175847024 2.6508834828188164 2.9111178361643413 2.80372704353586 2.1854027236756313 1.1183798470838613 3.2263057756221993 1.0987088632906363 1.0 10.576484968133514 -8.378301812733374 8.310940684658574 1.0103874354332854 2.3024432510961046 0.4263973304510269 0.5891038371594902 0.30964864731822994 19.889599321180185 0.58048000047427 0.1500402290008567 4.185026258446856e-09 8.378301812733374 1.2920558156628192 SAPSS(ph)PTLDCEK ddPTM_PC-9_AZD4547_30min_R2 1 SAPSSPTLDCEK 12 0 J3QSD2;J3QRZ1;A6NIZ0;Q9GZM8-3;Q9GZM8;Q9GZM8-2 J3QSD2 NDEL1 Nuclear distribution protein nudE-like 1 1 SAPS(0.033)S(0.749)PT(0.218)LDCEK 193.15 1.8548e-05 3467100.0 13504.0 12087.0 12792.0 11437.0 14731.0 17562.0 12667.0 14378.0 14627.0 13862.0 True False 17797.991099350864 15993.88637583237 12622.369721855684 8800.376349888566 12685.854925569056 16463.845363746757 13794.338460769482 12156.210473571195 15400.153358387659 13376.695599264422 1.3305222479854866 1.1956530113993076 0.9436089524642979 0.6578886605128769 0.94835490808856 1.2307856780901927 1.0312216764152147 0.9087603424450847 1.1512673846921138 1.0 13.707434155370086 -5.082884021582616 3.5249678807097724 0.9791023676368851 1.3111218430128684 0.3886757558027427 0.144172307883228 0.2558730337666409 5.860307902881991 0.04080606447607238 0.14523589752297925 8.26258572613551e-06 5.082884021582616 0.3320194753759833 SAPSS(ph)PTLDCEK ddPTM_PC-9_Lapatinib_30min_R1 3 SAPSSPTLDCEK 12 0 J3QSD2;J3QRZ1;A6NIZ0;Q9GZM8-3;Q9GZM8;Q9GZM8-2 J3QSD2 NDEL1 Nuclear distribution protein nudE-like 1 1 SAPS(0.193)S(0.807)PT(0.001)LDCEK;S(0.001)APS(0.171)S(0.705)PT(0.123)LDCEK;S(0.003)APS(0.096)S(0.897)PT(0.003)LDCEK 119.39 0.00054118 3325500.0 23972.199999999997 35742.9 40124.3 33167.2 43816.0 44605.0 44003.0 46303.0 48372.0 48356.0 True False 23630.352032036913 35660.139511087225 36825.43493827709 35606.426530535726 41238.829025570434 42697.34812933355 46281.26003166745 48454.40641741204 42923.83598025818 56714.27016968015 0.41665619536914833 0.628768375303036 0.6493151516911211 0.6278212947818409 0.7271332047858565 0.7528501733618332 0.8160425919826036 0.8543600450546943 0.75684366301174 1.0 15.791424164324521 -4.481330604115232 0.18335278636663585 1.013359835344176 1.7184342376418385e-13 0.8705099952402127 0.05360509010259995 6.545890467940216 0.1965582538244042 0.142270880497331 1.566788533781291 3.301181448694963e-05 4.481330604115232 -1.013359835344004 down SAPT(ph)APTPPPPPPPATPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAPTAPTPPPPPPPATPR 18 0 A6NHN7;A6NHB5;Q14202-2;Q14202 A6NHN7 ZMYM3 Zinc finger MYM-type protein 3 1 S(0.003)APT(0.728)APT(0.269)PPPPPPPATPR 112.57 0.00042886 8838800.0 12746.0 14570.0 12464.0 18856.0 16952.0 15484.0 16859.0 12406.0 13857.0 12530.0 True False 14903.646055024852 16016.413310224525 12761.189029983225 17799.559451976816 13630.377290950215 14671.991781975856 15261.993471409925 12080.355645243535 14059.632410131557 14801.589812574583 1.0068949514033667 1.0820738524059015 0.8621498900842428 1.202543758972116 0.9208725186648955 0.991244316844355 1.031105014033304 0.8161525753794877 0.9498731276951952 1.0 13.853464521048021 -7.725537319682196 24.99997808719688 0.9122593683269059 1.013443782234563 0.16051102859440336 0.09545970525202471 265.6012579890038 184948.28124326063 0.04239380636059693 0.02447497320615549 1.881320034160707e-08 7.725537319682196 0.10118441390765709 SAPT(ph)SPTATNISSK ddPTM_PC-9_AZD4547_30min_R2 2 SAPTSPTATNISSK 14 0 Q9H792;H0YN99;H3BUZ5 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 SAPT(0.883)S(0.058)PT(0.058)ATNISSK;SAPT(0.932)S(0.068)PTATNISSK 164.93 0.0012270999999999998 29246000.0 85890.0 87268.0 108271.0 135155.0 119869.0 99993.0 83692.0 115012.0 99937.0 105347.0 True False 113201.23337701765 115475.67438124742 106835.25579698524 103997.10287393443 103227.25843955159 93740.42190280902 91140.42586711295 97239.53811283714 105219.46579457093 101658.83359513101 1.1135405490471755 1.1359138236933122 1.0509195513935363 1.0230011421153606 1.015428318316803 0.9221079820386484 0.8965322800189806 0.9565281704894011 1.0350253103790328 1.0 16.633376057353573 -5.763026553064993 1.1424902330157456 0.9590765204976823 1.1322722417018674 0.696253700486777 0.03989265797840807 0.31109341945330243 0.7886185913105482 0.015626356295690442 0.042805038919507224 1.7257323762935373e-06 5.763026553064993 0.17319572120418503 SAPT(ph)SPTATNISSK ddPTM_PC-9_Lapatinib_30min_R1 1 SAPTSPTATNISSK 14 0 Q9H792;H0YN99;H3BUZ5 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 SAPT(0.794)S(0.203)PT(0.002)ATNISSK 136.39 0.00013393 9333700.0 41589.0 35582.0 36827.0 33224.0 45795.0 51404.0 51643.0 47824.0 58464.0 40195.0 True False 40995.93323351148 35499.61206515157 33799.226216330986 35667.40379201498 43101.42813643413 49205.570748576625 54316.821848860345 50046.07763009551 51879.16866678688 47142.652193529095 0.8696144855239747 0.7530253478191946 0.7169564002801341 0.7565845817412616 0.9142766927811993 1.0437590686790144 1.1521800179141384 1.061588080039437 1.1004719983469222 1.0 15.524745304849834 -6.58076327210541 2.3255924803151036 1.0847118701198524 0.768512349721265 0.8797093730132974 0.051883952300612046 0.09293432975415805 1.0193194717503764 0.019076315193814548 0.019743474079728672 2.6256493584146593e-07 6.58076327210541 -0.31619952039858734 SAPTAPT(ph)PPPPPPPATPR ddPTM_PC-9_AZD4547_30min_R2 2 SAPTAPTPPPPPPPATPR 18 0 A6NHN7;A6NHB5;Q14202-2;Q14202 A6NHN7 ZMYM3 Zinc finger MYM-type protein 3 1 S(0.001)APT(0.249)APT(0.75)PPPPPPPATPR;SAPT(0.018)APT(0.982)PPPPPPPATPR 175.19 5.7506000000000006e-08 26896000.0 34287.2 33888.2 51939.0 64451.0 51819.0 51057.0 41915.0 54573.0 43237.0 45938.0 True False 45189.8163819359 44841.8979301301 51250.25492366025 49592.81770802374 44624.82631104897 47864.39771875741 45645.35379988576 46139.99681278351 45522.419549915045 44329.724602438975 1.0194021457884177 1.0115537222999789 1.1561148954406208 1.1187260501342071 1.006656971394624 1.0797359592918374 1.029678262367874 1.0408365318435777 1.0269050836244187 1.0 15.435986779365289 -7.278512101827134 20.370626516313273 1.0277579352088422 1.0668009360115556 0.16116756604432336 0.045500198135891075 166.10223709111668 198181.91847135307 0.02037932218412347 0.013818728327119778 5.266085404861322e-08 7.278512101827134 0.03904300080271339 SAPTAPT(ph)PPPPPPPATPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAPTAPTPPPPPPPATPR 18 0 A6NHN7;A6NHB5;Q14202-2;Q14202 A6NHN7 ZMYM3 Zinc finger MYM-type protein 3 1 SAPT(0.01)APT(0.99)PPPPPPPATPR 153.75 5.941600000000001e-13 0.0 8174.8 8888.1 12008.0 11174.0 12163.0 9085.2 14418.0 9193.6 9516.8 7744.8 True False 9558.632180340266 9770.451828593461 12294.316260593603 10547.95700659679 9779.747462826064 8608.756118419467 13052.222662719516 8952.27774142439 9655.965195983252 9148.870932196938 1.0447881767247678 1.067940721975762 1.3438069409556468 1.1529244520737691 1.0689567636601944 0.9409637738054993 1.426648463996339 0.978511753829569 1.0554269775521408 1.0 13.159377995159534 SAPTAPT(ph)PPPPPPPATPR ddPTM_PC-9_Lapatinib_30min_R1 2 SAPTAPTPPPPPPPATPR 18 0 A6NHN7;A6NHB5;Q14202-2;Q14202 A6NHN7 ZMYM3 Zinc finger MYM-type protein 3 1 S(0.085)APT(0.142)APT(0.773)PPPPPPPATPR;S(0.093)APT(0.005)APT(0.902)PPPPPPPATPR 182.28 2.2838000000000003e-33 12046000.0 40516.0 34202.0 41415.0 28938.0 36250.0 37059.0 32617.0 33145.0 34410.0 27403.0 True False 39938.234410275574 34122.807370364615 38010.01856652315 31066.197054338107 34117.846270242095 35474.072958748366 34305.7486637933 34685.03770177143 30534.383446636162 32139.572037797698 1.2426498511960977 1.0617069614441206 1.182654782142759 0.9666026983123095 1.0615526003307652 1.1037506323055308 1.0673990501008563 1.0792003596370274 0.9500556949148621 1.0 14.972063098137514 -1.5228787453903951 0.6745320346029999 1.0427681657752643 20.105332984384972 0.4606312107769195 0.0631014109138323 238.90785437041575 1.403248581212473 0.02492138479213479 6836.154243613066 0.029999999992397493 1.5228787453903951 19.062564818609708 SAPTAPTPPPPPPPAT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 SAPTAPTPPPPPPPATPR 18 0 A6NHN7;A6NHB5;Q14202-2;Q14202 A6NHN7 ZMYM3 Zinc finger MYM-type protein 3 1 SAPTAPTPPPPPPPAT(1)PR 207.81 6.435899999999999e-20 14459000.0 21795.0 20341.0 31474.0 39284.0 30025.0 29002.0 24940.0 32021.0 27570.0 28898.0 True False 28725.356635837667 26915.83046006503 31056.63419525372 30227.68073174977 25856.547019225483 27188.500355277494 27159.61168481809 27072.89021937846 29027.293914729464 27886.289815866636 1.0300888653711697 0.9651994093796789 1.1136882819593745 1.0839620806978394 0.927213594564083 0.9749773288165385 0.9739413835312332 0.9708315590973536 1.0409163107174488 1.0 14.767268380595063 -6.253639048361118 24.998962466367463 0.9791695396607905 1.046978827682903 0.3505349605334388 0.04455500217705876 735.1175664565146 2355945.104846174 0.013897436371680312 0.01760489753718898 5.576490306847369e-07 6.253639048361118 0.06780928802211261 SAPTAPTPPPPPPPAT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SAPTAPTPPPPPPPATPR 18 0 A6NHN7;A6NHB5;Q14202-2;Q14202 A6NHN7 ZMYM3 Zinc finger MYM-type protein 3 1 SAPT(0.051)APT(0.005)PPPPPPPAT(0.943)PR;SAPTAPTPPPPPPPAT(1)PR 124.45 0.00010979999999999999 8235200.0 18805.0 16415.5 16720.5 20392.2 22460.3 17829.0 21405.5 21078.0 17481.9 13436.6 True False 21988.315084319966 18045.12235373992 17119.18013284937 19249.691146404406 18059.36544761263 16894.01585383928 19377.816077600408 20524.724833987057 17737.539714994506 15872.549215932931 1.3853045774303225 1.1368761317574716 1.078540056795985 1.2127661968174266 1.1377734730527445 1.0643542901653753 1.2208383047978755 1.2930956807734608 1.1174978558068978 1.0 13.954246230837628 -12.041308318903049 1.0986418638743878 0.3355957952469956 1.1789964006035174 0.2522209131248174 0.09431631671520567 24422.271597219617 1797.328791420155 39624.43667933291 0.028134527425649525 9.092675266830089e-13 12.041308318903049 0.8434006053565217 SAPTS(ph)PTATNISSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SAPTSPTATNISSK 14 0 Q9H792;H0YN99;H3BUZ5 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 SAPT(0.009)S(0.987)PT(0.003)AT(0.001)NISSK;SAPT(0.145)S(0.845)PT(0.005)AT(0.005)NISSK 143.56 0.00016708 13592800.0 36661.0 38967.0 35731.0 42298.0 54108.0 52035.0 60162.0 43208.0 42441.0 47695.0 True False 42866.983212244275 42835.38623606858 36582.96255057208 39928.180191966225 43505.92581752795 49306.192997617785 54463.0198248392 42073.835782660244 43061.61933451636 56341.72594658772 0.7608390139287252 0.760278204410649 0.6493049677827218 0.7086786838908409 0.7721795008333933 0.875127486232146 0.9666551549462729 0.7467615710343428 0.7642935783568119 1.0 15.781916138797323 -6.585491582279671 3.6160343360089837 0.8603273172494555 0.7190411049448445 0.45085526135493215 0.07858537388246149 0.24490392591427224 6.5163603980885885 0.027922236642553687 0.02843653574605793 2.597218081538668e-07 6.585491582279671 -0.14128621230461103 SAPTS(ph)PTATNISSK ddPTM_PC-9_Lapatinib_30min_R1 1 SAPTSPTATNISSK 14 0 Q9H792;H0YN99;H3BUZ5 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 SAPT(0.125)S(0.791)PT(0.076)AT(0.009)NISSK 192.54 5.6645e-07 12589000.0 56092.0 44555.0 48284.0 45323.0 64696.0 57623.0 60226.0 58563.0 68462.0 57503.0 True False 55292.11779398701 44451.83563495104 44314.27590162995 48656.20461309579 60890.70847722987 55158.59861577373 63344.20759191879 61284.05077474251 60751.088623179494 67442.31693206879 0.8198430942056742 0.6591089638827965 0.6570692988834512 0.7214491854143253 0.9028561183412779 0.8178633404800161 0.9392353417472621 0.9086883956918445 0.9007859069309699 1.0 16.041366479426543 -6.2446735780235905 4.575753768198051 0.9047448991353404 0.7040568574011934 0.7231318601831558 0.059626737851725294 0.10681202363729816 5.969665174025037 0.018110245661501746 0.02257608633021825 5.692806496046582e-07 6.2446735780235905 -0.200688041734147 SAPYQWPS(ph)PEAGIELMR ddPTM_PC-9_AZD4547_30min_R2 1 SAPYQWPSPEAGIELMR 17 0 Q8N4X5-2;Q8N4X5;Q8N4X5-4;F6QUH3 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 SAPY(0.005)QWPS(0.995)PEAGIELMR 62.298 0.025798 3898900.0 14043.0 11478.0 14445.0 15790.0 17677.0 15353.0 14823.0 18334.0 10157.0 16627.0 True False 18508.381887454383 15188.039035476444 14253.449861804671 12149.859453068144 15222.853677230605 14392.97448295205 16142.218284044046 15500.901573407586 10693.878284073524 16044.89379086493 1.153537201847483 0.9465964208578102 0.8883480344332222 0.7572415007187894 0.948766247732824 0.8970439237900477 1.006065761135454 0.9660956174252108 0.6664972933732989 1.0 13.969826619284495 -4.762384671699727 2.826438786750661 0.8922666405249009 1.2081899689521411 0.37580400410001846 0.10123827423305534 0.49441085307385935 5.240644876651082 0.02577451086410251 0.3745853127701778 1.7282848711964963e-05 4.762384671699727 0.31592332842724025 SAPYQWPS(ph)PEAGIELMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAPYQWPSPEAGIELMR 17 0 Q8N4X5-2;Q8N4X5;Q8N4X5-4;F6QUH3 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 SAPYQWPS(1)PEAGIELMR 80.459 0.0050466 5760200.0 20975.0 17088.0 24217.0 21246.0 30059.0 22990.0 22137.0 22692.0 17868.0 14936.0 True False 24525.65322486631 18784.383709342274 24794.425123483936 20055.655500461362 24169.154730336984 21784.363928418024 20040.02310199901 22096.359044161407 18129.285697065072 17643.778566689056 1.390045399411781 1.064646307951668 1.4052786385732075 1.1366984359192684 1.36984006226238 1.2346767925066955 1.135812435315528 1.2523598026716734 1.0275171856493732 1.0 14.106871939065 -8.250746004961306 1.0641883087329267 0.9898224063696927 1.258385816449599 0.40988361658144057 0.11058095047199018 0.47275912686817323 1.0868325781635293 0.09582133023523436 0.032447499326556196 5.6137619821272194e-09 8.250746004961306 0.26856341007990625 SAQGS(ph)SSPVPS(ph)MVQKSPR ddPTM_PC-9_AZD4547_30min_R2 1 SAQGSSSPVPSMVQKSPR 18 1 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 2 S(0.002)AQGS(0.5)S(0.444)S(0.054)PVPS(0.894)MVQKS(0.105)PR 64.069 0.036313 0.0 13607.0 10457.0 16519.0 20749.0 22446.0 16812.0 13374.0 16263.0 12868.0 17989.0 True False 17933.742956817765 13837.020752219663 16299.947266677149 15965.638618854407 19329.76034616272 15760.742982308973 14564.260091129001 13749.927036561996 13548.176209457342 17359.210585425455 1.0330966876958494 0.7970996540497658 0.9389797529365967 0.9197214666120204 1.1135160928568784 0.9079181858385581 0.8389932260719819 0.7920825067993724 0.7804603868814287 1.0 14.0834137218948 -7.140172069098776 4.3732238271195145 0.8360630583022485 0.9528102420173945 0.2084360261074516 0.09500880997988177 0.34377991570333216 10.687817747225857 0.037560634758370626 0.02874747711207382 7.241489926894387e-08 7.140172069098776 0.11674718371514603 SAQGS(ph)SSPVPSMVQK ddPTM_PC-9_Lapatinib_30min_R1 1 SAQGSSSPVPSMVQK 15 0 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 SAQGS(0.515)S(0.24)S(0.24)PVPS(0.006)MVQK 140.49 7.1431e-05 7461800.0 54483.0 48377.0 46580.0 42316.0 52750.0 43540.0 50649.0 40941.0 52284.0 34677.0 True False 53706.062429041434 48264.986028774016 42750.3722039997 45428.05980203786 49647.34871049024 41677.89569669728 53271.35739253967 42843.26832246866 46395.225345071914 40670.87324580196 1.3205042858179832 1.1867211637447672 1.0511299313793905 1.116967898070075 1.2207101728659056 1.0247602859375355 1.3098159233165305 1.053414025893603 1.1407481974796503 1.0 15.311708346839856 -14.522878709018002 0.023348109690967213 2.229600642959115e-06 1.9019514285147456 0.24465528460736619 0.0947529025655218 3949.907862200929 6.944637914345505 400.85357037968663 197.83639144602168 3.00000025049135e-15 14.522878709018002 1.9019491989141026 SAQGSS(ph)SPVPSMVQK ddPTM_PC-9_Lapatinib_30min_R1 1 SAQGSSSPVPSMVQK 15 0 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 SAQGS(0.002)S(0.497)S(0.497)PVPS(0.004)MVQK 164.63 0.0003018 10900000.0 67204.0 60859.0 69289.0 58461.0 67031.0 59412.0 57132.0 67169.0 68228.0 54992.0 True False 66245.65863629594 60718.08472466584 63592.32588327476 62760.41696017904 63088.36836801646 56871.087256136394 60090.01541097705 70289.91695249 60543.44416730861 64497.293927766004 1.0271075668769611 0.9414051509303211 0.9859688990129607 0.9730705451064011 0.9781552763852779 0.8817592769059333 0.9316672336404547 1.089811876932565 0.9386974317886031 1.0 15.976951011110291 SAQGSSS(ph)PVPSMVQK ddPTM_PC-9_AZD4547_30min_R2 1 SAQGSSSPVPSMVQK 15 0 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 SAQGSS(0.025)S(0.955)PVPS(0.02)MVQK 136.57 2.9177e-05 36601000.0 74404.0 86004.0 110050.0 121780.0 111090.0 113510.0 101090.0 124520.0 95174.0 104810.0 True False 98062.92430065914 113803.11110011462 108590.66509460735 93705.50248224438 95667.07105298113 106412.20175600122 110086.81416272116 105278.29518494119 100204.70333842796 101140.63380168125 0.9695699998572587 1.125196736687079 1.073660120694263 0.9264871986662073 0.945881664540161 1.0521211678844782 1.0884528801607252 1.0409099807637467 0.990746246804341 1.0 16.62600319874707 -4.902618518290992 0.0035978334219306423 0.23598152301202865 1.8259950567566932 0.007098077395592872 0.061522469567380174 415111.4587179328 242.0196264207483 52139.91999082792 54840.301934615825 1.2513577328451557e-05 4.902618518290992 1.5900135337446646 SAQGSSS(ph)PVPSMVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SAQGSSSPVPSMVQK 15 0 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 SAQGSS(0.013)S(0.979)PVPS(0.008)MVQK;SAQGSS(0.001)S(0.978)PVPS(0.02)MVQK;SAQGS(0.014)S(0.096)S(0.889)PVPS(0.001)MVQK 138.81 8.8697e-06 91513000.0 150674.0 156291.0 154703.0 153770.0 190836.0 159901.0 159353.0 157096.0 144978.0 129065.0 True False 176180.13225284882 171806.53758876483 158391.70623439428 145154.76542906617 153443.05572768836 151515.51007037723 144257.9302241883 152972.39645697072 147098.02897857042 152463.46282202203 1.15555641326678 1.1268702311275909 1.0388830432068343 0.9520626302349721 1.0064250994142108 0.9937824267263863 0.9461803343177871 1.0033380694989382 0.9648083957681393 1.0 17.218104023203686 -5.34869294973593 2.403228838895384 0.9812019834402164 1.1511819943930048 0.9015096642685975 0.021005384765448692 0.07992600559809503 0.8775768605510879 0.005603004100162887 0.016526890186709314 4.480299535972538e-06 5.34869294973593 0.16998001095278847 SAQGSSS(ph)PVPSMVQK ddPTM_PC-9_Lapatinib_30min_R1 3 SAQGSSSPVPSMVQK 15 0 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 SAQGS(0.003)S(0.012)S(0.976)PVPS(0.009)MVQK;SAQGSS(0.032)S(0.556)PVPS(0.412)MVQK;SAQGS(0.002)S(0.005)S(0.639)PVPS(0.354)MVQK 103.77 0.0027609 36071100.0 107448.0 108771.0 100910.0 92301.0 104863.0 98531.0 99939.0 95644.0 104505.0 84404.0 True False 105915.77181644987 108519.1474323702 92613.56932386475 99089.12344710973 98695.16450859015 94317.05881697926 105113.35241471736 100087.96940558843 92734.54641356332 98993.11893873967 1.0699306472199765 1.0962291985115205 0.9355556256508818 1.0009698099160758 0.9969901500897865 0.9527637862925188 1.0618248373380892 1.0110598643480089 0.9367777013971106 1.0 16.59504062577227 -5.245001306863638 24.882073948979006 0.9896940627427686 1.0830799400812359 0.523617155418549 0.036587840763633556 617.4803465340518 934667.4043504263 0.009296503186108926 0.024427282722337677 5.6885121907424026e-06 5.245001306863638 0.09338587733846726 SAQGSSSPVPS(ph)MVQK ddPTM_PC-9_AZD4547_30min_R2 4 SAQGSSSPVPSMVQK 15 0 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 SAQGS(0.036)S(0.141)S(0.355)PVPS(0.468)MVQK;SAQGS(0.005)S(0.025)S(0.409)PVPS(0.56)MVQK;SAQGSS(0.023)S(0.426)PVPS(0.551)MVQK;SAQGS(0.006)S(0.039)S(0.252)PVPS(0.703)MVQK 110.22 0.000484 111200900.0 144568.0 149677.0 172462.0 222706.0 183365.0 181514.0 172186.0 225191.0 180060.0 172874.0 True False 190537.6167987966 198057.16315673525 170175.04119533114 171364.5724734007 157907.93486029268 170163.9008857265 187510.22043151924 190392.90532438256 189577.6040002246 166821.73387875012 1.1421630285732658 1.187238368477142 1.0201011417314383 1.0272316951096578 0.9465669202015596 1.0200343620058856 1.1240155348571428 1.1412955668160392 1.1364083059945531 1.0 17.347947732742668 -10.823896352394863 14.753176844012899 1.0000000019322755 1.0794602458962343 0.10442751290530439 0.07214084928386165 0.0 0.0 0.07893695564829349 0.01914502387662416 1.500042789144243e-11 10.823896352394863 0.0794602439639589 SAQGSSSPVPS(ph)MVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAQGSSSPVPSMVQK 15 0 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 SAQGSS(0.022)S(0.459)PVPS(0.519)MVQK 120.86 6.5991e-05 44087000.0 48663.0 53320.0 48580.0 51740.0 62678.0 51924.0 53112.0 43573.0 44111.0 39740.0 True False 56900.68476193893 58613.2572203962 49738.331440675975 48841.17554334328 50396.695837787694 49201.01403302209 48080.84686241909 42429.25491940968 44756.03992518677 46944.54741833312 1.2120829338258285 1.2485636872389174 1.0595124285137278 1.0404014572365325 1.0735367281037291 1.0480666390194606 1.0242051421640124 0.9038164654419462 0.9533810077314394 1.0 15.518669978975831 -4.444828320166065 0.3932580080522133 0.9561764344801953 1.5513443768411863 0.7787645793671317 0.04701330085403377 3.5312073585735697 0.3529994448926088 0.04112414640111381 1.0451519079682647 3.5906384719895825e-05 4.444828320166065 0.595167942360991 SAQGSSSPVPS(ph)MVQK ddPTM_PC-9_Lapatinib_30min_R1 4 SAQGSSSPVPSMVQK 15 0 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 SAQGSS(0.002)S(0.084)PVPS(0.914)MVQK;SAQGS(0.002)S(0.008)S(0.037)PVPS(0.953)MVQK;SAQGSS(0.008)S(0.003)PVPS(0.989)MVQK;SAQGS(0.003)S(0.011)S(0.33)PVPS(0.656)MVQK 136.26 3.0126999999999998e-05 92787000.0 250650.0 242973.0 264742.0 227943.0 260231.0 259435.0 250154.0 247353.0 258793.0 185231.0 True False 247075.68503641983 242410.41094671722 242975.93469367264 244706.68861555675 244924.72421383107 248339.569822523 263105.7501070774 258845.9233865221 229645.00712889628 217247.93154520716 1.137298216277865 1.115823792763127 1.1184269187995086 1.1263936410121156 1.1273972666702452 1.1431159231582648 1.2110851792037785 1.191477044432337 1.057064182363041 1.0 17.728982915395115 -8.478439096210773 4.676175280329285 1.000467879597127 1.1447783377918062 0.727606190572237 0.02981612593846773 0.10202687512389931 5.0974286026228155 0.03295192521148459 0.00859111276369171 3.323233856980147e-09 8.478439096210773 0.14431045819467925 SAQGSSSPVPSMVQKS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 SAQGSSSPVPSMVQKSPR 18 1 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 SAQGSSSPVPS(0.014)MVQKS(0.986)PR 112.88 0.00050981 0.0 16477.0 17070.0 24033.0 37096.0 30950.0 24136.0 22737.0 29097.0 21180.0 29934.0 True False 21716.3432571093 22587.543677956364 23714.306717116768 28544.09032748675 26653.126735887723 22626.772104509262 24760.548952594596 24600.727232542857 22299.53156017301 28886.019771200485 0.7517942391897346 0.7819541721866529 0.8209613821825344 0.9881628051762728 0.9226998716680597 0.7833122141344054 0.8571810567436153 0.8516482169367589 0.7719835317154273 1.0 14.818083806991346 -12.045827262132649 2.2697014430906615 3.445361457944009 0.8410297723466589 0.328945240222989 0.06974675723295633 10680268.18674654 1594804.4595375904 131945884.72146942 0.019888819282756418 8.998554221305008e-13 12.045827262132649 -2.60433168559735 SAQGSSSPVPSMVQKS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 SAQGSSSPVPSMVQKSPR 18 1 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 SAQGSSSPVPS(0.026)MVQKS(0.974)PR 95.209 0.0021046999999999997 0.0 32831.0 12821.0 18683.0 16921.0 14744.0 15303.0 11938.0 11294.0 19689.0 9025.7 True False 32362.823919531955 12791.3137622199 17146.95585846558 18165.42678680128 13876.786907819303 14648.52636303533 12556.091226917384 11818.76047077407 17471.417485638467 10585.780219010721 3.057197792696699 1.20834869963088 1.6198103024727282 1.7160215318072136 1.310889383750699 1.3837927918367727 1.1861280857095666 1.116475141770757 1.650461007518559 1.0 13.369839985844884 -4.758051149778776 24.99991644506725 1.3721530002167595 3.0572001394771067 0.8319961096949772 0.2293971235247944 37.60170579447939 277398.6227448635 0.057427049429825135 0.405566936750115 1.7456165478248966e-05 4.758051149778776 1.6850471392603472 SAQQEASADVAT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 SAQQEASADVATPK 14 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 SAQQEASADVAT(1)PK 125.45 0.00050215 0.0 9241.2 7569.0 6768.2 11280.0 10401.0 7641.0 6931.0 10243.0 8436.8 8824.8 True False 12179.709371099018 10015.53123013776 6678.449245736678 8679.570274262738 8957.000684328537 7163.207062087968 7547.845572873864 8660.179710724009 8882.752023931434 8515.846438060067 1.4302406061086264 1.17610519435568 0.7842378669357555 1.0192257854100018 1.0518039221910824 0.841162075219356 0.8863294597634012 1.016948787617737 1.0430850401707044 1.0 13.055934219298855 -4.959549910464021 3.6399458920428422 0.9551037094114978 1.417152076806515 0.7438798284409716 0.08762894589985878 0.11498635035770473 3.075241146345997 0.022919447386408262 0.11253135664649402 1.0976151417009644e-05 4.959549910464021 0.4620483673950171 SAS(ph)ADNLTLPR ddPTM_PC-9_AZD4547_30min_R2 1 SASADNLTLPR 11 0 Q8ND76-3;Q8ND76-2;Q8ND76 Q8ND76-3 CCNY Cyclin-Y 1 S(0.175)AS(0.825)ADNLTLPR 107.46 0.0023061999999999996 54066000.0 61284.0 73637.0 77183.0 92018.0 83613.0 64760.0 84020.0 91844.0 69807.0 64788.0 True False 80771.03721361198 97438.72019998069 76159.50298952371 70804.67176392814 72004.77821543727 60710.54696254639 91497.6172316928 77651.62016516035 73496.85550618487 62519.79183993247 1.291927481467111 1.5585259856502736 1.2181662917962455 1.1325161149801521 1.1517117395366403 0.971061245980821 1.463498430480245 1.2420326088731939 1.1755774186573853 1.0 15.932025354432179 -5.406396024699707 6.2990956708900665 1.176527703949029 1.4231344983114729 0.34808750156711565 0.14082593761979187 0.2583208067984546 12.373614056269481 0.03702697820898966 0.0779831076061047 3.922870533097599e-06 5.406396024699707 0.24660679436244393 SAS(ph)ADNLTLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASADNLTLPR 11 0 Q8ND76-3;Q8ND76-2;Q8ND76 Q8ND76-3 CCNY Cyclin-Y 1 S(0.03)AS(0.97)ADNLTLPR 99.834 0.0043978 39967000.0 49166.0 49464.0 49047.0 38248.0 81000.0 41699.0 47828.0 46675.0 48145.0 34402.0 True False 57488.832727236135 54374.45902381235 50216.466491783336 36105.088561689096 65128.63146336529 39512.23103310585 43297.38559526626 45449.83070625041 48849.02954360853 40638.810273917836 1.4146288323832332 1.3379933776927055 1.2356775740556678 0.888438621070103 1.6026215094482017 0.9722782425661947 1.065419614979593 1.1183848739641944 1.202029026301492 1.0 15.310570546496068 -1.5228787452849788 0.4036622180628461 1.1005196527920769 6.585754217406496 0.227849742846564 0.18422730104149151 115.38363696911898 1.5215178504941105 0.12942211821383015 504.78704042262825 0.029999999999679394 1.5228787452849788 5.485234564614419 SAS(ph)ADNLTLPR ddPTM_PC-9_Lapatinib_30min_R1 1 SASADNLTLPR 11 0 Q8ND76-3;Q8ND76-2;Q8ND76 Q8ND76-3 CCNY Cyclin-Y 1 S(0.2)AS(0.796)ADNLT(0.004)LPR 95.428 0.0062229 47893000.0 61240.0 71453.0 58509.0 44730.0 62682.0 42571.0 37139.0 38499.0 59705.0 42528.0 True False 60366.706369959415 71287.55496855937 53698.61587127134 48019.593414905794 58995.167997553515 40750.33756784795 39061.87569747734 40287.80408750935 52980.39417847753 49878.908135002006 1.2102651927859203 1.4292124193178573 1.0765796181009202 0.9627234278051195 1.1827678312018677 0.8169853569679851 0.783134137414409 0.8077122293548724 1.0621803114671446 1.0 15.606142264014167 -5.664936470406777 0.9433172792914418 0.8962084237474448 1.3550023027259226 0.5405975887892343 0.13203312624444508 0.5561997791263382 0.8727702537603675 0.05395322732278826 0.19804940292150508 2.1630349142952444e-06 5.664936470406777 0.4587938789784778 SAS(ph)APTLAETEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASAPTLAETEK 12 0 Q86W92-2 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.049)AS(0.945)APT(0.006)LAETEK 109.6 0.0022296 0.0 17698.0 43616.0 35511.0 27041.0 34162.0 26388.0 31444.0 23300.0 21864.0 20994.0 True False 20693.921848566577 47945.908231897985 36357.716916217454 25525.98043810484 27468.201333968926 25004.166826580924 28465.396685154137 22688.39968839066 22183.719637375798 24800.046011587445 0.8344307844790956 1.9332991644247752 1.4660342524860583 1.0292714951487676 1.1075867085542836 1.0082306627535331 1.1477961239206618 0.9148531288123356 0.8945031645106946 1.0 14.598055176799804 -5.764058656494149 9.01349772713023 1.0199258650804275 1.4640178775409907 0.3251643057818585 0.2584582005025111 0.10745437661400241 103.15098334333346 0.06869792308667634 0.10921712892261111 1.7216360324187327e-06 5.764058656494149 0.4440920124605632 SAS(ph)APTLAETEKETAEHLDLAGASSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASAPTLAETEKETAEHLDLAGASSR 26 1 Q86W92-2 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.195)AS(0.785)APT(0.02)LAETEKETAEHLDLAGASSR 81.808 8.6315e-06 2714100.0 6357.0 10666.0 12287.0 8519.7 12323.0 9619.0 14698.0 10197.0 8207.1 8314.5 True False 7433.114543526827 11724.8499908617 12579.968678706993 8042.368830240081 9908.396611395674 9114.562706718269 13305.699035695061 9929.339554614578 8327.113311192225 9821.853032454217 0.7567935010802632 1.193751316795256 1.280814184160481 0.8188239839942412 1.0088113290491614 0.9279880972155805 1.3547035362603388 1.0109436092970638 0.8478148964026498 1.0 13.261779519846929 -4.74341792145557 24.54951218735604 1.0541574127438194 0.7567923316997213 0.21406760559284288 0.16790540269275156 1531.3500522348306 2085924.345306664 0.04266435851259643 1.323135360540467 1.8054359193390004e-05 4.74341792145557 -0.2973650810440981 SAS(ph)APTLAETEKETAEHLDLAGASSR ddPTM_PC-9_Lapatinib_30min_R1 1 SASAPTLAETEKETAEHLDLAGASSR 26 1 Q86W92-2 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.214)AS(0.594)APT(0.187)LAET(0.004)EKET(0.002)AEHLDLAGASSR 48.331 0.012445 4189800.0 6933.8 9326.7 12412.0 11649.0 13573.0 11383.0 14618.0 13789.0 13142.0 9835.1 True False 6834.922740496809 9305.104599180739 11391.53327170555 12505.706319924826 12774.662825544714 10896.175625069023 15374.84851357668 14429.687279219379 11661.809568604842 11535.083930553015 0.5925334207922949 0.8066785343914383 0.9875553000124045 1.0841452385795756 1.1074616277137284 0.9446117332712497 1.3328770389657303 1.2509390799489042 1.0109861045498045 1.0 13.493740880818034 -4.515746326803673 0.7687407495001095 1.1359906560487165 0.03613911704046946 0.6962260541447024 0.1099228811405767 2.1097347625293823 0.7197589043068257 0.04357637314062943 2.191283152855521 3.0496757976878648e-05 4.515746326803673 -1.099851539008247 SAS(ph)ASHQADIK ddPTM_PC-9_AZD4547_30min_R2 2 SASASHQADIK 11 0 C9JXK0;A0A494C1L1;Q14739 C9JXK0 LBR Lamin-B receptor 1 S(0.032)AS(0.966)AS(0.002)HQADIK;S(0.208)AS(0.64)AS(0.152)HQADIK 108.59 0.0021656999999999996 136688000.0 128938.1 125548.0 294373.0 240927.0 224152.0 142237.0 205611.0 240377.0 186571.0 160206.0 True False 169937.7337209135 166128.93577504752 290469.42168009875 185385.00243504447 193032.3639451599 133342.89790475141 223909.98067871452 203232.257963947 196432.76216775447 154597.23670291153 1.09922879182816 1.074591883516627 1.8788784836969104 1.1991482279291807 1.2486145811008826 0.8625179902859167 1.4483440031273058 1.3145917889496115 1.2706097880988518 1.0 17.238155006955495 SAS(ph)ASHQADIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SASASHQADIK 11 0 C9JXK0;A0A494C1L1;Q14739 C9JXK0 LBR Lamin-B receptor 1 S(0.007)AS(0.99)AS(0.003)HQADIK;S(0.019)AS(0.972)AS(0.01)HQADIK;S(0.105)AS(0.894)AS(0.001)HQADIK 124.42 0.00051256 49538800.0 34173.0 41836.0 54927.0 39128.0 66307.0 40528.0 42423.0 32655.3 38701.0 31945.5 True False 39957.813952484226 45989.20159550813 56236.66799180747 36935.78501468757 53314.61933878219 38402.64033453355 38404.38632407751 31798.132976150366 39266.928909901246 37736.96626956112 1.0588507212545715 1.2186777619324243 1.4902275818914552 0.9787693253042499 1.4127955850490852 1.0176398404741234 1.0176861078272403 0.8426255769743458 1.0405428096527782 1.0 15.203690826764928 -6.9198905452417465 8.06341475321337 0.9699063990523348 1.2311329279386074 0.4158064655969256 0.1476797201216296 0.24192073005058695 21.338001907971957 0.05042771220475091 0.04446223561388908 1.2025674781802837e-07 6.9198905452417465 0.2612265288862726 SAS(ph)ASHQADIK ddPTM_PC-9_Lapatinib_30min_R1 1 SASASHQADIK 11 0 C9JXK0;A0A494C1L1;Q14739 C9JXK0 LBR Lamin-B receptor 1 S(0.174)AS(0.826)ASHQADIK 122.97 0.00061719 64212000.0 21855.0 23205.0 15601.0 7307.2 9840.0 15197.0 11308.0 9752.4 17858.0 4735.8 True False 21543.343692283845 23151.270248210963 14318.346001601536 7844.595864104623 9261.230546184333 14547.059735937264 11893.47290953106 10205.532106886574 15846.643986923236 5554.376719943155 3.878624871613736 4.168113078301952 2.5778492751834943 1.4123269377711396 1.6673752993619626 2.6190264847729203 2.1412794826874437 1.8373856548554417 2.85300129716182 1.0 12.439409314458832 -5.381108889845851 3.7353793467710132 1.9933234927977292 4.027178103500879 0.7141678411260677 0.5197409719101119 0.1192402649973981 2.929740024764319 0.13699981929644395 0.31402893619457345 4.158063430739135e-06 5.381108889845851 2.03385461070315 SAS(ph)ASPLTPCSVTR ddPTM_PC-9_AZD4547_30min_R2 4 SASASPLTPCSVTR 14 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.305)AS(0.364)AS(0.33)PLTPCSVTR;S(0.004)AS(0.961)AS(0.035)PLTPCSVTR;S(0.044)AS(0.951)AS(0.005)PLTPCSVTR;S(0.049)AS(0.951)ASPLTPCSVTR 205.87 9.069499999999999e-11 64140000.0 70276.3 66389.0 108995.0 124028.0 108065.0 99386.0 92223.0 106787.0 86549.0 101058.0 True False 92622.70156215284 87847.94594234586 107549.65508393217 95435.26081349817 93062.0400876804 93171.37770876514 100430.6683403759 90285.52287113968 91123.80344671455 97519.99017966136 0.9497816949275094 0.9008198809341894 1.1028472714752446 0.9786225433131968 0.9542868074148895 0.955407989040147 1.0298469898874292 0.9258155451493217 0.9344115322287965 1.0 16.573410360227072 -6.0079052997507745 24.969776378281693 0.965603926885857 0.9868863309874066 0.02088139812639933 0.055072228661605674 1784.4642920303268 5636458.535799525 0.01632256455589841 0.022976298441076418 9.819620417847393e-07 6.0079052997507745 0.02128240410154969 SAS(ph)ASPLTPCSVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASASPLTPCSVTR 14 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.004)AS(0.871)AS(0.124)PLT(0.001)PCSVTR 89.74700000000001 0.0052028 17768000.0 20808.0 26617.0 14939.0 21749.0 27346.0 23857.0 28253.0 22654.0 19459.0 15808.0 True False 24330.383423266656 29259.359854375198 15295.202416472994 20530.474041209352 21987.74760490353 22605.896922151762 25576.67130599351 22059.356503897074 19743.551062188784 18673.865263940854 1.3029109442193798 1.5668614633776374 0.8190699782978491 1.0994228431568263 1.1774609752251863 1.2105633516486618 1.369650629073668 1.181295687427583 1.0572825059583935 1.0 14.188732958423476 -1.5228797628117834 0.021200336729266075 1.165662359881049e-10 2.724286952553858 0.12646439103576157 0.1835967148434508 7222.044512516703 11.838282435896994 554.3048613466434 1036.2154187319306 0.029999929711500176 1.5228797628117834 2.724286952437292 SAS(ph)ASPLTPCSVTR ddPTM_PC-9_Lapatinib_30min_R1 2 SASASPLTPCSVTR 14 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.004)AS(0.965)AS(0.028)PLT(0.003)PCSVTR;S(0.205)AS(0.78)AS(0.013)PLT(0.002)PCSVTR 143.76 0.00016896 24797000.0 32689.0 30659.0 28621.0 26738.0 28612.0 25701.0 35248.0 31315.0 25751.0 24205.0 True False 32222.84886557157 30588.01096918336 26267.891860254957 28704.401715353248 26929.09841335633 24601.828141957205 37072.96897021142 32770.00922102796 22850.651209948504 28388.801998864838 1.1350549018186833 1.0774674806779962 0.9252906079413041 1.0111170494796162 0.9485817124101652 0.866603252329596 1.3059011427003446 1.1543287111001834 0.804917770424487 1.0 14.793034348486211 SAS(ph)ATSS(ph)S(ph)S(ph)SS(ph)RK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASATSSSSSSRK 13 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8YFE7 Q14004 CDK13 Cyclin-dependent kinase 13 5 S(0.138)AS(0.819)AT(0.237)S(0.232)S(0.712)S(0.83)S(0.58)S(0.578)S(0.874)RK 43.813 0.045076 0.0 6499.7 6547.0 9401.8 16056.0 14804.0 10737.0 9486.9 9412.2 9258.1 9678.1 True False 7599.970835073354 7196.942892384355 9625.974568525058 15156.434374254333 11903.262471403194 10173.932818591751 8588.232152791914 9165.13972305024 9393.48219789557 11432.66291820256 0.6647594606303864 0.6295071361656008 0.8419713445061888 1.3257133952688271 1.0411627244297885 0.8899005324816568 0.751201379262055 0.8016627262278437 0.8216355424019105 1.0 13.480873857592922 -5.387568858644463 4.666481825227202 0.9418252026882699 0.6506201595869603 0.3693882688543777 0.15391821129033034 0.26220290327695883 8.694728826839478 0.04625051083746121 0.10054277590120948 4.096671507539753e-06 5.387568858644463 -0.29120504310130957 SAS(ph)DASISSGTHGQYSILQTAR ddPTM_PC-9_AZD4547_30min_R2 1 SASDASISSGTHGQYSILQTAR 22 0 E7ER60;A0A1W2PR85;O15056-2;O15056;O15056-3 E7ER60 SYNJ2 Synaptojanin-2 1 S(0.236)AS(0.761)DAS(0.002)ISSGTHGQYSILQTAR 92.613 0.00056497 0.0 5306.5 8105.4 10368.0 13100.0 9957.1 10198.0 9688.4 14430.0 8795.4 9581.6 True False 6993.856617943227 10725.31204026405 10230.513545669142 10079.997392982443 8574.728537056788 9560.317447869793 10550.648831082266 12200.17506841232 9260.306887835024 9246.151100412062 0.7564073463639958 1.159975856309126 1.1064618601369398 1.0901830700704447 0.9273835614339732 1.0339780676354866 1.1410854869776104 1.3194868800996136 1.0015309924388247 1.0 13.17463722392142 -7.24751755838149 6.230122225859755 1.1424649558543734 1.0226883935658795 0.1080787635155972 0.134896589206483 0.31882169760607343 55.67243426006066 0.052733420679253414 0.0388612535681994 5.655648910264435e-08 7.24751755838149 -0.11977656228849387 SAS(ph)DSGCDPASKK ddPTM_PC-9_AZD4547_30min_R2 1 SASDSGCDPASKK 13 1 Q7LBC6;H0Y9V5 Q7LBC6 KDM3B Lysine-specific demethylase 3B 1 S(0.019)AS(0.738)DS(0.243)GCDPASKK 97.69 0.0043303000000000005 7475800.0 54267.0 55336.0 68107.0 85168.0 77078.0 84866.0 67831.0 77489.0 60152.0 66029.0 True False 71522.77717627923 73222.27984554144 67203.85667967678 65533.83343248314 66377.05016312616 79559.31560412992 73867.82759394126 65514.85557007646 63331.511917258154 63717.3448076635 1.1225009044582306 1.149173432549166 1.054718411172619 1.0285085423804596 1.041742250300781 1.248628859916979 1.1593048614457788 1.028210697853762 0.9939446175673199 1.0 15.959398528512024 -7.909443822780506 5.724004952398108 1.001409712769808 1.1126552216636263 0.3969195579682875 0.061387671412437284 0.23792387907373855 11.829493928965409 0.03866713074142771 0.01812886190411342 1.231845318106854e-08 7.909443822780506 0.11124550889381823 SAS(ph)EPSLHR ddPTM_PC-9_AZD4547_30min_R2 3 SASEPSLHR 9 0 P04049;P04049-2;H7C155;Q96II5;P10398 P04049;Q96II5 RAF1;ARAF RAF proto-oncogene serine/threonine-protein kinase;Serine/threonine-protein kinase A-Raf 1 S(0.043)AS(0.956)EPS(0.001)LHR;S(0.048)AS(0.944)EPS(0.008)LHR;S(0.053)AS(0.937)EPS(0.01)LHR 80.834 0.010264 131094800.0 121179.0 110213.0 338481.0 568174.0 427129.0 336814.0 215034.0 432364.0 272764.0 360600.0 True False 159711.40132021878 145837.19691731705 333992.5207804437 437190.2625007946 367829.5111332138 315752.96733543946 234171.60942394426 365552.07853631536 287181.7481812571 347975.5037580971 0.458973116197414 0.41910190614652865 0.9598161858330866 1.25638229639497 1.0570557615714198 0.907399986278753 0.6729542938940145 1.050510954329811 0.8252930021789633 1.0 18.40862622346883 -5.263527210360299 22.892494914398647 0.9690193588607829 0.43903737901379786 0.6782121517242539 0.14522976455101308 31.586986044646103 346362.9580916618 0.04081083224210937 0.09247329788362023 5.450957420976982e-06 5.263527210360299 -0.5299819798469851 SAS(ph)EPSLHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SASEPSLHR 9 0 P04049;P04049-2;H7C155;Q96II5;P10398 P04049;Q96II5 RAF1;ARAF RAF proto-oncogene serine/threonine-protein kinase;Serine/threonine-protein kinase A-Raf 1 S(0.037)AS(0.963)EPSLHR;S(0.013)AS(0.987)EPSLHR;S(0.181)AS(0.815)EPS(0.004)LHR;S(0.041)AS(0.958)EPS(0.001)LHR;S(0.046)AS(0.952)EPS(0.002)LHR 105.13 0.0015055 103277000.0 204395.3 257530.0 507671.0 504137.0 599833.0 565627.0 485459.0 441429.0 474678.0 358108.0 True False 238995.3872988092 283095.87644352316 519775.8019929889 475891.8383242063 482300.0295872204 535964.524390574 439472.8091012037 429841.9564826866 481619.2677474501 423030.1456186327 0.564960652979721 0.6692096990618202 1.2286968372735632 1.1249596352720193 1.1401079440376816 1.2669653213644805 1.0388687748446992 1.0161024242234378 1.1384986926715057 1.0 18.69040094956658 -5.189390503338649 5.259273490870545 1.1229273760721983 0.5980738558367236 0.8532172408914782 0.08349105758459782 0.07422746492527309 3.804699906363365 0.021910190236228026 0.06074878534371311 6.465609878860894e-06 5.189390503338649 -0.5248535202354747 SAS(ph)EPSLHR ddPTM_PC-9_Lapatinib_30min_R1 3 SASEPSLHR 9 0 P04049;P04049-2;H7C155;Q96II5;P10398 P04049;Q96II5 RAF1;ARAF RAF proto-oncogene serine/threonine-protein kinase;Serine/threonine-protein kinase A-Raf 1 S(0.154)AS(0.846)EPSLHR;S(0.258)AS(0.74)EPS(0.002)LHR;S(0.29)AS(0.709)EPSLHR 83.081 0.0084087 93093300.0 208121.0 129746.0 279495.0 156493.0 208110.0 242125.0 153656.0 169931.0 286882.0 155504.0 True False 205153.15637528317 129445.58110857064 256515.99998189998 168002.0172653444 195869.37896000207 231769.87817094248 161611.55583541788 177826.6146236153 254570.32815861324 182382.65920394452 1.1248501215561078 0.7097471967651353 1.406471432654449 0.9211512651401833 1.073947379728554 1.2707890058329065 0.8861125094941186 0.9750193104968684 1.395803358004265 1.0 17.47660904017983 -5.241998771950131 24.994988509631902 1.1041036843579892 0.9172987474042564 0.1344494556129323 0.19996393319167552 1699.6255006939066 2185218.2827620935 0.048305385716134484 0.12740893662707897 5.727976506773395e-06 5.241998771950131 -0.1868049369537328 SAS(ph)EPSLNR ddPTM_PC-9_AZD4547_30min_R2 2 SASEPSLNR 9 0 H7C560;P15056;A0A2R8Y8E0;A0A2U3TZI2 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 S(0.031)AS(0.969)EPSLNR;S(0.161)AS(0.837)EPS(0.002)LNR 124.67 0.0014513 83081000.0 25032.0 38430.0 108623.0 125470.0 109039.0 86933.0 47197.0 155172.0 66559.0 76275.0 True False 32991.655302055 50851.74596039028 107182.58804699252 96544.82999217599 93900.8170001444 81497.06576737236 51397.441567295886 131193.7328978291 70077.17285710841 73604.63546630323 0.44822795593028697 0.6908769486898771 1.4561934498821278 1.3116677961998053 1.2757459690583335 1.1072273539712367 0.6982908242351942 1.7824112851953544 0.9520755372695281 1.0 16.16750900661515 -5.093159195448867 4.651266965577282 1.2099641804394081 0.4969772116829267 0.45227905626055975 0.2814308871557884 0.1740651113793153 6.1898256337806385 0.07053451790134431 0.21128912173661002 8.069391835407359e-06 5.093159195448867 -0.7129869687564814 SAS(ph)EPSLNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SASEPSLNR 9 0 H7C560;P15056;A0A2R8Y8E0;A0A2U3TZI2 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 S(0.035)AS(0.955)EPS(0.01)LNR;S(0.008)AS(0.991)EPS(0.002)LNR 93.44200000000001 0.0062531999999999996 80427000.0 30840.0 27109.0 107140.0 47196.0 85530.0 60652.0 41042.0 52782.0 46753.0 38363.0 True False 36060.60288223492 29800.202362860466 109694.62393071267 44551.7611314965 68771.01048224217 57471.302348256235 37154.20464165171 51396.528427151774 47436.674177013825 45317.9082186591 0.7957252287162584 0.6575811535491525 2.4205579701833466 0.9830939441541315 1.5175239366835238 1.2681808275650535 0.8198570080150769 1.1341328505094126 1.0467533926793724 1.0 15.467793650411897 -7.132720609870933 7.7578327280323345 1.012167791467487 1.2980784523630347 0.07666101739207465 0.46078912220232987 0.8039298336616525 46.9146604782703 0.17956820008349614 0.13902585979844426 7.366808662867158e-08 7.132720609870933 0.28591066089554773 SAS(ph)EPSLNR ddPTM_PC-9_Lapatinib_30min_R1 1 SASEPSLNR 9 0 H7C560;P15056;A0A2R8Y8E0;A0A2U3TZI2 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 S(0.013)AS(0.985)EPS(0.002)LNR 131.09 0.001245 62392000.0 38688.0 40616.0 49750.0 33010.0 34482.0 38331.0 27811.0 32455.0 30304.0 27010.0 True False 38136.30202548972 40521.956147439596 45659.7470405536 35437.66551813189 32453.836554220354 36691.67248392519 29250.917499731913 33962.977782802554 26890.844404732987 31678.64251143726 1.203848997371683 1.2791569630172615 1.4413416554724086 1.1186611138825622 1.024470557490057 1.1582463633243762 0.92336398218993 1.0721096325557686 0.848863533057779 1.0 14.951222894134322 -5.9604044455048975 5.24165792367001 1.0159761584653035 1.3048706874101197 0.670182689680503 0.09495867632467486 0.11391400228462047 7.628454682996919 0.027159725702317134 0.04021568885557077 1.0954575540051408e-06 5.9604044455048975 0.28889452894481615 SAS(ph)FAFEFPKDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASFAFEFPKDR 12 1 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 S(0.077)AS(0.923)FAFEFPKDR 63.754 0.021806 1472500.0 10609.0 7897.3 7912.7 11368.0 11606.0 11435.0 9758.1 9636.4 9065.4 8193.5 True False 12404.894162698776 8681.291752562543 8101.368777081858 10731.087815553268 9331.887614368106 10835.328469832983 8833.742125473942 9383.454710609769 9197.96432494816 9678.916690289681 1.281640762043537 0.8969280375428792 0.8370119339088341 1.1087075298746163 0.9641458763386475 1.1194773977860006 0.9126788057114227 0.9694736519453325 0.9503092772950474 1.0 13.240629868008414 -4.752451274202622 24.995625125456005 0.9746153968835373 1.281641352775778 0.5531980455779232 0.08315234481381056 276.05264060068254 767636.7962055532 0.020945568867569642 0.25031994633661125 1.7682705982462873e-05 4.752451274202622 0.3070259558922407 SAS(ph)FFAVHSNPMDMPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASFFAVHSNPMDMPGR 17 0 J3KNG8;Q8TF40;Q8TF40-2 J3KNG8 FNIP1 Folliculin-interacting protein 1 1 S(0.011)AS(0.906)FFAVHS(0.082)NPMDMPGR 98.40799999999999 0.00081217 5220400.0 26358.0 21386.0 26764.0 25663.0 27667.0 28319.0 29975.0 23731.0 25197.0 24595.0 True False 30819.888805770035 23509.060744849827 27402.15526303523 24225.185310568577 22245.849959221294 26833.901787249695 27135.55099979314 23108.0863950729 25565.458456959288 29053.878806087116 1.0607839666252383 0.8091539481442461 0.9431496374692032 0.8338021051252243 0.7656757332711299 0.9235910277710558 0.9339734353854308 0.7953528872789094 0.8799327149255898 1.0 14.826443161449488 -4.749818153193844 24.868641460838667 0.8702949802321471 1.0607844186181157 0.3746650067690368 0.07123971318637469 508.03067309729954 1087078.2918476365 0.017081196966891133 0.26712840053480785 1.7790241630933667e-05 4.749818153193844 0.19048943838596855 SAS(ph)FNTDPYVR ddPTM_PC-9_AZD4547_30min_R2 3 SASFNTDPYVR 11 0 Q9UKV8-2;Q9UKV8 Q9UKV8-2 AGO2 Protein argonaute-2 1 S(0.003)AS(0.875)FNT(0.122)DPYVR;S(0.003)AS(0.989)FNT(0.008)DPYVR;S(0.002)AS(0.98)FNT(0.017)DPY(0.001)VR 112.84 0.0016370999999999998 14522400.0 82350.0 77705.0 108362.0 148526.0 123622.0 98209.0 100178.0 132183.0 91709.0 109579.0 True False 108535.58701359181 102821.62164590499 106925.04907752707 114285.62540382531 106459.21917104746 92067.97570482896 109093.64792949913 111757.15461316306 96556.5505123658 105742.67256325175 1.0264123686553264 0.9723758550210703 1.0111816401611002 1.0807900219796645 1.0067763239799628 0.8706794851412231 1.0316899061184872 1.0568784758708802 0.9131275782216387 1.0 16.690198169716616 -6.5352488213897475 24.999101579449373 0.97684170860835 1.021462739739874 0.14320844099318764 0.05598202564308152 517.9885928072816 1046812.4532134241 0.019018297638401297 0.019031041053300536 2.9157560042070993e-07 6.5352488213897475 0.044621031131523936 SAS(ph)FNTDPYVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SASFNTDPYVR 11 0 Q9UKV8-2;Q9UKV8 Q9UKV8-2 AGO2 Protein argonaute-2 1 S(0.049)AS(0.901)FNT(0.049)DPYVR;S(0.006)AS(0.966)FNT(0.028)DPYVR;S(0.05)AS(0.775)FNT(0.169)DPY(0.007)VR 110.98 0.0018694000000000002 12801100.0 71854.0 72950.0 74270.0 73638.0 88206.0 80071.0 74781.0 77409.0 77411.0 64698.0 True False 84017.46301881016 80191.99389024553 76040.87847054368 69512.30159761725 70922.66749206922 75871.93580306048 67697.20231244466 75377.09577161515 78542.98942777612 76427.23525091387 1.099313127617102 1.0492593854399128 0.994944776176951 0.9095226507854876 0.9279763589409858 0.9927342727231945 0.8857732729725452 0.9862596170612338 1.0276832489087973 1.0 16.22179922147034 -5.204928615089852 2.2534069941908865 0.9576173761822268 1.093411891165617 0.5345886810747423 0.04213351967804346 0.25739533624244065 2.383363825453943 0.011824585037507695 0.04765120374008134 6.238373670975964e-06 5.204928615089852 0.13579451498339024 SAS(ph)FNTDPYVR ddPTM_PC-9_Lapatinib_30min_R1 2 SASFNTDPYVR 11 0 Q9UKV8-2;Q9UKV8 Q9UKV8-2 AGO2 Protein argonaute-2 1 S(0.313)AS(0.685)FNT(0.001)DPYVR;S(0.002)AS(0.996)FNT(0.002)DPYVR 115.12 0.0013912 8193500.0 65567.0 54552.0 63954.0 60148.0 54509.0 56467.0 54489.0 54785.0 60810.0 49904.0 True False 64632.00255648488 54425.688195664916 58695.94898957917 64571.484567846055 51302.88778881729 54052.03804100611 57310.17380327536 57330.5111024754 53960.93744231169 58529.8399070998 1.104257292674482 0.9298793279129226 1.0028380238651433 1.103223324552668 0.8765253393866559 0.9234954021196542 0.9791616360857927 0.979509104987678 0.9219389208642976 1.0 15.836884712112145 -6.265105693917385 24.999871205942302 0.9462028705400093 1.0252365169099993 0.35713456652646824 0.05741947523195641 408.14089681623705 2783030.0495715234 0.01768213009409918 0.02082138357042753 5.431181371595632e-07 6.265105693917385 0.07903364636999 SAS(ph)FSQGTR ddPTM_PC-9_AZD4547_30min_R2 2 SASFSQGTR 9 0 Q9UQC2-2;Q9UQC2 Q9UQC2-2 GAB2 GRB2-associated-binding protein 2 1 S(0.046)AS(0.926)FS(0.028)QGTR;S(0.001)AS(0.984)FS(0.014)QGTR 87.667 0.010713 27413500.0 35108.8 38534.9 57834.0 69500.0 74842.0 44591.9 41623.1 59058.0 48128.0 54109.0 True False 46272.66809159431 50990.552833959 57067.08337193572 53477.84876429612 64451.48016695664 41803.561443779676 45327.47526537095 49931.94311783059 50671.94782474066 52214.660379497785 0.8862006906735217 0.9765562480605652 1.0929321948504571 1.024192216814539 1.2343560160790334 0.8006096590488204 0.8680986323750732 0.9562820624499645 0.9704544175228825 1.0 15.67216731062239 -6.787380463837018 24.99994296882176 0.9131697613517464 1.0409109483851808 0.28438407883499384 0.0979104380041529 308.12987191894706 296948.6388142171 0.03567307023753834 0.03147094989816304 1.6316219386197575e-07 6.787380463837018 0.1277411870334344 SAS(ph)FSQGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SASFSQGTR 9 0 Q9UQC2-2;Q9UQC2 Q9UQC2-2 GAB2 GRB2-associated-binding protein 2 1 S(0.035)AS(0.745)FS(0.219)QGTR;S(0.007)AS(0.987)FS(0.007)QGTR 100.82 0.0036972000000000003 22969000.0 26195.2 30186.8 26811.6 39695.0 43517.0 40854.0 51868.0 49916.0 42516.0 29923.9 True False 30629.529981216594 33183.546006388875 27450.89022755924 37471.017842926376 34990.15623939833 38711.54432064334 46954.68754819917 48605.757890373745 43137.716067630296 35348.866192537935 0.8664925719083578 0.9387442818008642 0.7765705999745491 1.0600345040440484 0.9898522925407061 1.0951283164158532 1.3283223086264417 1.3750301813254284 1.2203422829085413 1.0 15.109376321185664 -6.715861797024534 1.384059333241241 1.2596978621914658 0.8928912552999005 0.6077663590560856 0.11529955537671734 0.25481290720865757 1.0205671170699662 0.05189184098790477 0.04880849218602665 1.9237038004489806e-07 6.715861797024534 -0.3668066068915653 SAS(ph)FSQGTR ddPTM_PC-9_Lapatinib_30min_R1 1 SASFSQGTR 9 0 Q9UQC2-2;Q9UQC2 Q9UQC2-2 GAB2 GRB2-associated-binding protein 2 1 S(0.003)AS(0.962)FS(0.035)QGTR 81.625 0.016959000000000002 17101000.0 42974.0 30130.0 31978.0 26106.0 35958.0 32384.0 37153.0 31784.0 34969.0 26626.0 True False 42361.18287953357 30060.235836181688 29348.892278649702 28025.92232706305 33843.02113614799 30999.01181079111 39076.600548974835 33260.80067319662 31030.422980105188 31228.268623085132 1.356501168566821 0.9625969405796647 0.9398181062447336 0.897453607349375 1.0837303068134214 0.9926586768206372 1.2513213915448362 1.0650862868717916 0.9936645337156575 1.0 14.930564964337607 SAS(ph)FSVK ddPTM_PC-9_Lapatinib_30min_R1 1 SASFSVK 7 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 S(0.001)AS(0.834)FS(0.166)VK 74.92 0.033477 2756100.0 24538.0 21003.0 17396.0 15816.0 16320.0 14455.0 18331.0 15224.0 14562.0 18135.0 True False 24188.083620281923 20954.368843920478 15965.768030501918 16979.161400629328 15360.089686354519 13836.793346250784 19280.08948572814 15931.362617944427 12921.874215341924 21269.610586631425 1.1372132800346069 0.9851787722475236 0.7506375335586479 0.7982826639666468 0.7221613025679363 0.6505428620751343 0.9064617994391605 0.7490199481112154 0.6075275408880171 1.0 14.376505999595635 -5.045837714917834 2.3615603852013543 0.7619160857359303 1.1473985205635966 0.5454442257506578 0.10879464319416178 0.2512665469858059 2.41146372574546 0.02805450925731799 0.15739172391231968 8.998337642862865e-06 5.045837714917834 0.3854824348276663 SAS(ph)ITNLSLDR ddPTM_PC-9_AZD4547_30min_R2 1 SASITNLSLDR 11 0 E9PDH4;Q9Y2I7-2;Q9Y2I7-3;Q9Y2I7-4;Q9Y2I7 E9PDH4 PIKFYVE 1-phosphatidylinositol 3-phosphate 5-kinase 1 S(0.002)AS(0.997)ITNLSLDR 119.88 0.00092138 7395900.0 12999.0 17218.0 16391.0 26546.0 18818.0 19314.0 17550.0 17489.0 10768.0 14791.0 True False 17132.4116040034 22783.381783658606 16173.644630310864 20426.2298316116 16205.445522324244 18106.29252678537 19111.916001145055 14786.47690723931 11337.174496692303 14273.171592030014 1.2003226818606982 1.5962382037346627 1.1331500168709563 1.4310925711155458 1.1353780354867442 1.2685542529941791 1.3390097553242437 1.035962947120731 0.7942996007294455 1.0 13.80101832625431 -7.903633101699683 3.800760552859163 0.899354589392856 1.3027885547107845 0.58804096774867 0.1397595214754629 0.14767015389462154 4.004079116008503 0.08194042972183857 0.03570508306382662 1.2484377672553251e-08 7.903633101699683 0.4034339653179285 SAS(ph)ITNLSLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SASITNLSLDR 11 0 E9PDH4;Q9Y2I7-2;Q9Y2I7-3;Q9Y2I7-4;Q9Y2I7 E9PDH4 PIKFYVE 1-phosphatidylinositol 3-phosphate 5-kinase 1 S(0.015)AS(0.977)IT(0.006)NLS(0.002)LDR;S(0.022)AS(0.962)IT(0.001)NLS(0.016)LDR 90.759 0.0085624 11637800.0 32665.0 37596.0 34342.0 35262.0 41687.0 32954.0 32166.0 37722.0 33107.0 26085.0 True False 38194.539336841895 41328.28241669193 35160.84352276028 33286.38446094647 33518.73160263342 31225.834227798507 29119.003618326802 36731.83746976278 33591.127242709495 30814.00401125363 1.2395188669052164 1.3412175321843394 1.1410670132294114 1.0802356113405418 1.087775921311362 1.0133650341706475 0.9449925302694258 1.192050129426474 1.0901253608729857 1.0 14.911298539753904 -5.474526708892726 2.9874016360137987 1.0612354961891808 1.2902897427668985 0.6516713419129669 0.06684646464539051 0.1609203768341403 2.8280826113326802 0.019181392980381833 0.043531200947737686 3.353306811477704e-06 5.474526708892726 0.22905424657771767 SAS(ph)ITNLSLDR ddPTM_PC-9_Lapatinib_30min_R1 1 SASITNLSLDR 11 0 E9PDH4;Q9Y2I7-2;Q9Y2I7-3;Q9Y2I7-4;Q9Y2I7 E9PDH4 PIKFYVE 1-phosphatidylinositol 3-phosphate 5-kinase 1 S(0.025)AS(0.955)IT(0.007)NLS(0.013)LDR 78.40100000000001 0.018432 9680300.0 29328.0 31143.0 32627.0 23169.0 28110.0 30330.0 20186.0 18442.0 34672.0 18008.0 True False 28909.777341903507 31070.890296920206 29944.534003862143 24872.925549518266 26456.62506638637 29032.856602683234 21231.132309143442 19298.882645830996 30766.874247653854 21120.6588058483 1.3687914571063666 1.4711136893285115 1.4177840889873434 1.1776586032738223 1.2526420368601638 1.3746188918427134 1.0052305898367409 0.9137443497021572 1.45671943903258 1.0 14.366367216192149 -6.213604747267514 0.6094349601973615 1.0958563864956712 1.46462250476346 0.34125004177564877 0.1602348527423279 1.145439106969506 0.8738254805257524 0.11247485021420484 0.2350774808414092 6.11498298200297e-07 6.213604747267514 0.3687661182677888 SAS(ph)LPAYR ddPTM_PC-9_AZD4547_30min_R2 2 SASLPAYR 8 0 O94929;A0A0C4DGA7;O94929-2;O94929-3;A0A0A0MRD5;O94929-4 O94929 ABLIM3 Actin-binding LIM protein 3 1 S(0.046)AS(0.953)LPAYR;S(0.045)AS(0.955)LPAYR 106.88 0.003819 36158000.0 46088.0 43466.0 80073.0 100025.0 111159.0 99449.0 104866.0 124027.0 119324.0 124488.0 True False 60743.02531004757 57515.534476042834 79011.17970123129 76965.78162084485 95726.49159400769 93230.4383088058 114198.8708476399 104861.47700692856 125631.22303522586 120129.71301119831 0.5056453044583998 0.4787785888632009 0.657715545311142 0.6406889660484764 0.7968594046760455 0.7760814204235632 0.9506296817423884 0.8729020854079085 1.0457964136109665 1.0 16.87423350734636 -6.183948611915918 0.44895966167770185 1.0241083379369456 0.38595886159689113 0.9285366647733896 0.05050255736420056 0.3663727620474044 0.13199206632936303 0.04174156703323461 0.10953625118710193 6.547136387611632e-07 6.183948611915918 -0.6381494763400544 SAS(ph)LPAYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASLPAYR 8 0 O94929;A0A0C4DGA7;O94929-2;O94929-3;A0A0A0MRD5;O94929-4 O94929 ABLIM3 Actin-binding LIM protein 3 1 S(0.001)AS(0.999)LPAYR 117.31 0.0035521999999999997 12596000.0 20008.0 34729.0 40029.0 49236.0 49290.0 37062.0 35935.0 43632.0 39390.0 31069.0 True False 23394.959223986913 38176.66560403487 40983.44317082787 46477.46654526573 39631.97833122559 35118.403476077816 32530.9766531298 42486.70623192539 39966.00423144131 36701.56375793133 0.6374376682773137 1.0401917982523228 1.1166674924572175 1.2663620234770456 1.079844406429712 0.9568639556533503 0.8863648662953699 1.157626593573792 1.0889455418041831 1.0 15.163553913401325 -4.76258602018334 4.8734631099831 1.0720870690920627 0.6080025740450874 0.6230000624080743 0.10018400598052428 0.12882555385978803 7.699051454018157 0.027454326237791555 0.20631726305479325 1.7274837859935133e-05 4.76258602018334 -0.46408449504697535 SAS(ph)LPAYR ddPTM_PC-9_Lapatinib_30min_R1 3 SASLPAYR 8 0 O94929;A0A0C4DGA7;O94929-2;O94929-3;A0A0A0MRD5;O94929-4 O94929 ABLIM3 Actin-binding LIM protein 3 1 S(0.075)AS(0.925)LPAYR;SAS(1)LPAYR;S(0.002)AS(0.998)LPAYR 123.35 0.0032885999999999996 51680400.0 132827.0 178904.0 200714.0 177209.0 179246.0 146403.0 119899.0 134169.0 141368.0 101509.0 True False 130932.86262251153 178489.75877982902 184212.069698446 190241.54101189465 168703.1026911949 140141.68497206175 126106.78354968727 140402.98154801535 125445.64716896419 119054.6953977597 1.0997706741852311 1.4992248578142826 1.5472894125090708 1.5979339611621441 1.4170218329278044 1.1771201841628403 1.0592340195266274 1.1793149449413263 1.0536808040191312 1.0 16.861264994612306 -6.817313764278923 3.271229158587179 1.0909637937245993 1.4555329767168492 0.6236544778573929 0.13272131704355866 0.1675461837175058 3.643766974930189 0.05035197765347209 0.045379855776716056 1.522952070655008e-07 6.817313764278923 0.36456918299224994 SAS(ph)LSHPGGEGEPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASLSHPGGEGEPAR 15 0 C9JXU1;A6NN40;Q2M3G4-2;Q2M3G4 C9JXU1 SHROOM1 Protein Shroom1 1 S(0.065)AS(0.467)LS(0.467)HPGGEGEPAR 132.51 6.4902999999999995e-06 6796300.0 4366.8 6507.7 7266.8 5085.4 12977.0 8280.8 10161.0 7292.0 9658.3 9760.2 True False 5106.012991768592 7153.741448109003 7440.068071492464 4800.481525089249 10434.250006173952 7846.540270484732 9198.476520730543 7100.592726512646 9799.534365791553 11529.64699829931 0.4428594381529425 0.6204649152887527 0.645298860632066 0.41635980059036914 0.9049930156329213 0.6805533830864157 0.7978107675011535 0.6158551712433195 0.8499422720606313 1.0 13.493060722409115 -5.940631677568469 0.10004428723973123 1.2514497506879088 2.8252867123714696e-14 0.5557785116970744 0.1205893421125312 29.51047196349017 0.7597077246777841 2.8341641680759175 6.874849558022629 1.1464848558795804e-06 5.940631677568469 -1.2514497506878806 SAS(ph)LSNLHSLDR ddPTM_PC-9_AZD4547_30min_R2 1 SASLSNLHSLDR 12 0 B0QY53;B0QY54;A0A087WUW0;Q9Y3M2 B0QY53 CBY1 Protein chibby homolog 1 1 S(0.018)AS(0.978)LS(0.004)NLHSLDR 100.68 0.003159 0.0 10907.0 9887.7 18541.0 32797.0 26339.0 21391.0 16029.0 29805.0 19877.0 23914.0 True False 14375.199120306555 13083.705660487938 18295.13422552582 25236.158358598852 22682.28449423416 20053.417388447037 17455.549947712487 25199.32210076435 20927.657640300247 23076.778138855105 0.6229292076133702 0.566964139524247 0.7927941290349245 1.093573730559377 0.9829051680331093 0.8689868779681363 0.756411915159076 1.0919774826944084 0.9068708601511267 1.0 14.494154195926372 -5.474085700851242 4.060535423830597 0.9505722711123371 0.6018965985283166 0.6907019660503273 0.09664421342748246 0.1262153811634458 4.312399856175828 0.02722756311481363 0.05766135528445306 3.356713685000737e-06 5.474085700851242 -0.34867567258402055 SAS(ph)LSNLHSLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASLSNLHSLDR 12 0 B0QY53;B0QY54;A0A087WUW0;Q9Y3M2 B0QY53 CBY1 Protein chibby homolog 1 1 S(0.023)AS(0.954)LS(0.023)NLHSLDR 112.67 0.00052483 3542800.0 14736.0 18207.0 26257.0 28517.0 34823.0 28018.0 29783.0 27476.0 24454.0 21191.0 True False 17230.51375073327 20014.470634128906 26883.066460227008 26919.2849433614 27999.683128997112 26548.686757129908 26961.738629752766 26754.784113228412 24811.59348757719 25032.760552136315 0.6883185621836184 0.7995311021508914 1.0739153759824858 1.0753622193323815 1.1185215897656 1.0605576920626207 1.0770581444103586 1.0687907974634119 0.9911648951341784 1.0 14.611529776259731 -5.148736640160666 3.1366312122526105 1.0652791707549907 0.7032454240639082 0.9194280965039119 0.037734158192548495 0.06236598124168646 1.1322007098391456 0.010006627408988215 0.03491526627991603 7.100081924041366e-06 5.148736640160666 -0.36203374669108246 SAS(ph)LSNLHSLDR ddPTM_PC-9_Lapatinib_30min_R1 4 SASLSNLHSLDR 12 0 B0QY53;B0QY54;A0A087WUW0;Q9Y3M2 B0QY53 CBY1 Protein chibby homolog 1 1 S(0.319)AS(0.681)LSNLHSLDR;S(0.048)AS(0.952)LSNLHSLDR;S(0.018)AS(0.981)LS(0.001)NLHSLDR;S(0.006)AS(0.991)LS(0.002)NLHSLDR 148.18 1.0016e-07 13947500.0 106554.0 93866.0 125188.0 110499.0 125662.0 125379.0 97366.0 104728.0 133150.0 94360.0 True False 105034.52042038961 93648.65904411004 114895.5258796549 118625.4650738583 118270.8082209977 120016.83244272404 102407.13506450309 109594.04520836059 118153.2448683406 110670.00027320313 0.9490785231869376 0.8461973327272638 1.038181310165542 1.071884564751207 1.0686799306861028 1.0844567827455232 0.9253378043887043 0.9902778073354441 1.0676176432336144 1.0 16.755904672864816 -5.2736744848639 24.657227976070367 1.0314265927041273 0.8976379293767237 0.5177950056287548 0.05140061847577928 447.1584803182069 901152.7850439876 0.014170579995235237 0.029845519131515032 5.325072379053365e-06 5.2736744848639 -0.13378866332740358 SAS(ph)LSSLLITPFPSPNSSLTR ddPTM_PC-9_AZD4547_30min_R2 2 SASLSSLLITPFPSPNSSLTR 21 0 J3KNG8;Q8TF40;Q8TF40-2;Q8TF40-3;A0A087WX11 J3KNG8 FNIP1 Folliculin-interacting protein 1 1 S(0.001)AS(0.927)LS(0.072)SLLITPFPSPNSSLTR;S(0.024)AS(0.941)LS(0.035)SLLITPFPSPNSSLTR 317.83 1.8261999999999995e-167 14187700.0 15348.71 17890.39 22002.5 31872.3 29212.3 22325.52 23089.7 29884.0 19896.1 22908.1 True False 20229.28050699921 23673.108701855497 21710.732473821885 24524.633657126284 25156.676386002357 20929.50170511533 25144.63856932416 25266.114466003724 20947.767227306806 22106.09439168297 0.915099707282989 1.0708860770431745 0.982115252434196 1.1094059955861424 1.137997329617262 0.9467751894242199 1.1374527821967677 1.1429479137440783 0.9476014557862394 1.0 14.43215653815136 -4.018873475321623 1.5959512458528853 1.0613555324865254 3.907669493471992e-15 0.21357363612007696 0.07589303839442808 16.019544901600316 6.265040522659422 0.020424921891832988 47.69142860965088 9.574729749427206e-05 4.018873475321623 -1.0613555324865214 SAS(ph)LSSLLITPFPSPNSSLTR ddPTM_PC-9_Lapatinib_30min_R1 1 SASLSSLLITPFPSPNSSLTR 21 0 J3KNG8;Q8TF40;Q8TF40-2;Q8TF40-3;A0A087WX11 J3KNG8 FNIP1 Folliculin-interacting protein 1 1 S(0.1)AS(0.873)LS(0.027)SLLITPFPSPNSSLTR 198.98 3.6865e-19 14311000.0 37960.0 31851.0 43478.0 30846.0 28952.0 22756.0 30404.0 29115.0 23032.0 25546.0 True False 37418.68343898857 31777.25096641962 39903.40666993342 33114.51773923954 27249.100281822062 21782.778926826893 31978.170352085443 30467.78918953309 20437.893622287836 29961.592062094678 1.2488883555132602 1.06059954693202 1.3318186359134245 1.1052322476926626 0.909467702028282 0.7270234132312665 1.0673054451115767 1.016894867481986 0.6821364358719921 1.0 14.870826665531155 -6.152678493341115 3.6606299067786927 0.900610208762393 1.2004842233503323 0.5454294965965919 0.1302357465528189 0.19364738849333857 4.728426632774225 0.03955350010301704 0.05236969234653995 7.035929945223499e-07 6.152678493341115 0.2998740145879394 SAS(ph)LSYPDR ddPTM_PC-9_AZD4547_30min_R2 2 SASLSYPDR 9 0 Q6P4Q7-2;Q6P4Q7 Q6P4Q7-2 CNNM4 Metal transporter CNNM4 1 S(0.001)AS(0.986)LS(0.013)YPDR;S(0.012)AS(0.595)LS(0.391)Y(0.002)PDR 94.363 0.005771500000000001 27518000.0 70429.0 126551.0 95875.0 80238.0 88481.0 59096.0 98130.0 117387.0 94452.0 69415.0 True False 92823.95698579561 167456.1359103135 94603.63485638796 61740.368764742314 76196.94044323365 55400.71777792835 106863.37989700057 99247.5364349079 99444.53989242033 66984.8019782816 1.385746531219004 2.499912382582061 1.4123149141660698 0.921707117754268 1.1375257997767745 0.8270639927530257 1.5953376996120516 1.481642604050495 1.4845836212916343 1.0 16.03154618261601 -5.503927557457238 23.39200188534897 1.2199682177301672 1.9461508805561658 0.4129000760292203 0.34621063862251106 296.7007635310771 366224.410270109 0.09034848716226374 0.18278424416832165 3.1338084160065014e-06 5.503927557457238 0.7261826628259986 SAS(ph)LSYPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SASLSYPDR 9 0 Q6P4Q7-2;Q6P4Q7 Q6P4Q7-2 CNNM4 Metal transporter CNNM4 1 S(0.044)AS(0.956)LS(0.001)YPDR;SAS(0.805)LS(0.195)YPDR 110.39 0.0023052 20773400.0 83451.0 90360.0 81011.0 53608.0 117047.0 49310.0 48508.0 43170.0 39720.0 46901.0 True False 97577.60606761937 99330.34363156428 82942.60947592818 50604.51755948097 94112.48057891992 46724.096794706085 43912.97107249258 42036.83324239589 40300.82985714265 55403.78003188827 1.7612084592686181 1.7928441628783014 1.4970568691917705 0.9133766239479503 1.6986653351946819 0.8433377067018443 0.7925988271417217 0.7587358338763369 0.7274021706451627 1.0 15.757696789889252 -5.8311722894891185 0.5540941423864788 0.7616288809835784 1.9997327789968482 0.6706226766326122 0.24565369148077237 0.890237910845921 0.4493500803053744 0.170959285819649 0.6268010595109972 1.475121220060305e-06 5.8311722894891185 1.2381038980132697 SAS(ph)LSYPDR ddPTM_PC-9_Lapatinib_30min_R1 1 SASLSYPDR 9 0 Q6P4Q7-2;Q6P4Q7 Q6P4Q7-2 CNNM4 Metal transporter CNNM4 1 SAS(0.726)LS(0.273)Y(0.001)PDR 119.22 0.0017503 13857000.0 60184.0 133680.0 49477.0 19301.0 45614.0 28722.0 35147.0 24474.0 68243.0 17917.0 True False 59325.765123606085 133370.47217327447 45409.19204674308 20720.45992624854 42931.07420057445 27493.627014252168 36966.73968440822 25611.151386729638 60556.75470935174 21013.929577098188 2.8231637926616853 6.3467649724412745 2.1609091188842573 0.9860345182097934 2.042981729955088 1.308352486543774 1.759154067247662 1.2187702111004353 2.8817434876791865 1.0 14.359058348856676 -5.422705146213972 6.6881926894519745 1.6180175421155336 4.561859432460509 0.6045978647413391 0.9518321738704232 0.13928545926582508 7.937137218027607 0.2271172534353014 0.47655305091312944 3.7782862151599736e-06 5.422705146213972 2.9438418903449755 SAS(ph)LVTR ddPTM_PC-9_AZD4547_30min_R2 2 SASLVTR 7 0 Q9H2K8 Q9H2K8 TAOK3 Serine/threonine-protein kinase TAO3 1 S(0.011)AS(0.984)LVT(0.005)R;S(0.005)AS(0.98)LVT(0.016)R 79.48899999999999 0.026793 66233000.0 182974.0 169897.0 244259.0 346673.0 313447.0 299199.0 185188.0 286359.0 201467.0 266918.0 True False 241155.92590437084 224812.88273308444 241019.9660640044 266752.89589445805 269930.2945390571 280490.0392317306 201669.3732433081 242108.7964251893 212116.13431696768 257573.28206351673 0.9362614164496401 0.8728113449190988 0.9357335672904524 1.03563884327365 1.0479747448048327 1.0889717946854547 0.7829592092303156 0.939960831673085 0.823517612609605 1.0 17.97462342567829 -10.326716405208481 5.630318074984041 1.0000000103161786 0.9439864244316823 0.034620580705112314 0.09267517231681043 1.2759992403315393e-08 2.768149074389625e-09 0.09508445643272881 0.023061363948458386 4.712849755644189e-11 10.326716405208481 -0.05601358588449623 SAS(ph)LVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASLVTR 7 0 Q9H2K8 Q9H2K8 TAOK3 Serine/threonine-protein kinase TAO3 1 S(0.002)AS(0.997)LVTR 93.598 0.013808 39407000.0 133300.0 139420.0 159370.0 180770.0 194260.0 163480.0 171690.0 155380.0 138830.0 99685.0 True False 155865.05720499074 153260.69620531966 163169.98521409032 170642.04296424706 156196.1475070785 154906.82100990776 155426.2802720428 151301.4396387186 140860.12610944416 117757.10139397444 1.3236149273369109 1.301498545659361 1.3856487913045694 1.4491019305352797 1.3264265650060487 1.3154775310887046 1.3198888086760927 1.2848604275042101 1.1961921993831608 1.0 16.845454539259542 -8.660272488618265 0.7897555862228873 0.9979070893597267 1.3573987338575102 0.8833787546039183 0.03916367595056349 0.2823680323283736 0.37754136179882486 0.042286812134083904 0.015309204304471314 2.1863893910790785e-09 8.660272488618265 0.3594916444977835 SAS(ph)LVTR ddPTM_PC-9_Lapatinib_30min_R1 2 SASLVTR 7 0 Q9H2K8 Q9H2K8 TAOK3 Serine/threonine-protein kinase TAO3 1 S(0.008)AS(0.992)LVT(0.001)R;S(0.006)AS(0.97)LVT(0.024)R 101.46 0.011192 69040000.0 457030.0 329260.0 408990.0 301430.0 305660.0 314350.0 285051.0 322970.0 349610.0 248726.0 True False 450512.66839096317 328497.61869967484 375364.42094705615 323598.1677410023 287681.67975068156 300905.9832856405 299809.5460147453 337976.36525995296 310233.24024348904 291717.9576934369 1.5443432826456363 1.1260795231704224 1.2867374498128168 1.1092843591105486 0.9861637659379304 1.031496263256646 1.0277377107164989 1.1585723687779568 1.0634698072633213 1.0 18.154214673418323 -1.5228787521466511 0.726698684467466 1.0572320365777599 69.40152703845825 0.7550779230649114 0.0797333785199233 167.17065554815193 0.7958563716474735 0.030912036348553447 18642.69374523343 0.029999999525691864 1.5228787521466511 68.3442950018805 SAS(ph)MDSLTFVK ddPTM_PC-9_Lapatinib_30min_R1 1 SASMDSLTFVK 11 0 H0Y4Z7;P43155-3;P43155-2;P43155 H0Y4Z7 CRAT Carnitine O-acetyltransferase 1 S(0.064)AS(0.934)MDS(0.002)LTFVK 68.786 0.032004000000000005 7205500.0 31105.0 19765.0 23266.0 18934.0 17662.0 20785.0 16601.0 13286.0 20706.0 16323.0 True False 30661.4369960416 19719.235356857982 21353.15928935718 20326.469521972424 16623.15588482803 19896.0740022015 17460.51855068316 13903.316062927595 18373.872236153682 19144.408800969675 1.6015870385346442 1.0300258191237115 1.1153731364259016 1.061744435845043 0.8683034330099584 1.0392629100771058 0.9120427134735429 0.726233763991886 0.9597513523229317 1.0 14.224635488519 -1.5228787453558643 0.7827360924835082 0.9211006694403212 142.18580502215758 0.7707378209337881 0.10416162814973724 213.17726211405096 0.7997683025459077 0.0382957521110385 53304.60611623319 0.029999999994782797 1.5228787453558643 141.26470435271725 SAS(ph)MKLPDNTVK ddPTM_PC-9_AZD4547_30min_R2 4 SASMKLPDNTVK 12 1 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 S(0.004)AS(0.988)MKLPDNT(0.009)VK;S(0.001)AS(0.999)MKLPDNTVK;S(0.008)AS(0.973)MKLPDNT(0.019)VK;S(0.002)AS(0.998)MKLPDNTVK 105.19 0.007437699999999999 153799000.0 685730.0 572847.0 661580.0 987361.0 887857.0 709023.0 601625.0 683430.0 636198.0 684747.0 True False 903777.8759299387 758008.5901163591 652807.0169313074 759740.1760253848 764593.381077387 664687.6797255327 655168.4594979426 577821.5971590449 669826.1274560406 660774.215950765 1.3677559658249139 1.1471521918053158 0.9879426302856055 1.1497727327816827 1.1571174580068024 1.005922543102165 0.9915163813637061 0.8744614774770496 1.0136989478202492 1.0 19.333797866936123 -1.5228787452803376 0.4279977500717169 0.9798399620083489 7.772892877607516 0.6582091460660401 0.07664351747139822 55.54930200092404 0.7009343887423631 0.05604496310154205 324.9306010380127 0.029999999999999995 1.5228787452803376 6.7930529155991675 SAS(ph)MKLPDNTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASMKLPDNTVK 12 1 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 S(0.008)AS(0.992)MKLPDNTVK 103.11 0.0047714 38036000.0 119870.0 105040.0 99947.0 127210.0 119660.0 122920.0 113490.0 106680.0 89335.0 87922.0 True False 140161.62345958184 115467.67701482371 102330.11553110823 120082.8361203848 96213.48198649746 116473.8588117071 102739.40560355363 103879.76303680312 90641.35536978464 103861.56260983113 1.3495042818305787 1.111746002210581 0.985254919719666 1.156181681682288 0.9263627425666159 1.1214337227840065 0.9891956468006069 1.000175237369 0.872713187556114 1.0 16.664302310660652 -1.5228795783243678 0.8570179315737969 1.0008911051317961 129.3757049864143 0.6436048294066242 0.07771525943261444 433.88665198022335 1.16900347563336 0.025890537451660433 108648.6552981309 0.029999942455412213 1.5228795783243678 128.3748138812825 SAS(ph)MKLPDNTVK ddPTM_PC-9_Lapatinib_30min_R1 2 SASMKLPDNTVK 12 1 E9PDI4;O00515 E9PDI4 LAD1 Ladinin-1 1 S(0.013)AS(0.987)MKLPDNTVK;S(0.015)AS(0.985)MKLPDNTVK 63.211999999999996 0.022866 209433000.0 240829.0 181739.0 207450.0 186273.0 209233.0 187934.0 171412.0 198503.0 204539.0 171793.0 True False 237394.73429737004 181318.1945115112 190394.26178015795 199972.1378085122 196926.3263079053 179896.50091555118 180286.87463464247 207726.17405082894 181501.66392884366 201487.1911502162 1.1782125352096622 0.8998993607307361 0.9449447416149245 0.9924806468686415 0.97736399611174 0.8928433608538006 0.8947808225696684 1.0309646626418119 0.9008099368139357 1.0 17.620328601768577 -4.754073263576013 24.99885570309529 0.9479887728063789 1.1782129402856547 0.675639849469566 0.04780419968513657 154.4195979799113 524019.5472594795 0.011739771320789233 0.11894558631888062 1.761678833843537e-05 4.754073263576013 0.23022416747927577 SAS(ph)NGHVPGTPVYR ddPTM_PC-9_Lapatinib_30min_R1 1 SASNGHVPGTPVYR 14 0 A0A087WX19;A0A087WX45;Q6IPM2-2;Q6IPM2-3;Q6IPM2-4;Q6IPM2;C9JP75 A0A087WX19 IQCE IQ domain-containing protein E 1 S(0.003)AS(0.995)NGHVPGT(0.002)PVYR 103.77 0.0011317999999999999 4460900.0 12687.0 9845.9 10909.0 10546.0 14914.0 13405.0 9081.6 10738.0 11062.0 8514.9 True False 12506.081053489144 9823.102423480295 10012.104129957768 11321.588020424693 14036.787842052148 12831.699398581244 9551.800811389923 11236.926680996268 9816.081071975861 9986.68911960894 1.2522749936145863 0.9836195265348312 1.0025448885055335 1.1336678137096177 1.4055496945920554 1.284880228562047 0.9564532045595461 1.1251903955768963 0.9829164555349892 1.0 13.285790746220957 -7.273212883610176 24.74617144328388 1.0265725509619832 1.168772428852249 0.2809823014747035 0.12526646620689152 1169.0304713274777 2457120.088767645 0.058567228893734516 0.03983320156889826 5.3307352805142346e-08 7.273212883610176 0.14219987789026578 SAS(ph)NKSPLVLEANR ddPTM_PC-9_Lapatinib_30min_R1 1 SASNKSPLVLEANR 14 1 Q92560;F8W6N3 Q92560 BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1;Ubiquitin carboxyl-terminal hydrolase 1 S(0.138)AS(0.798)NKS(0.063)PLVLEANR 52.821000000000005 0.04135 20917000.0 40785.0 48683.0 53973.0 44618.0 58032.0 49296.0 43674.0 53039.0 51403.0 40096.0 True False 40203.39842094699 48570.277504574595 49535.54828180497 47899.35656128473 54618.67185530177 47187.72499458862 45935.2260214768 55503.385568389036 45613.45284241322 47026.54017543831 0.8549087020002588 1.032826938222059 1.0533530235693822 1.0185600808094806 1.1614435519079243 1.0034275287645866 0.9767936541814425 1.180256624479003 0.9699512801121793 1.0 15.521187574059853 -4.758837487360682 4.188772216143352 1.0507946172246445 0.8347214298440431 0.4065204998553765 0.0684740486503785 0.22303983499082394 7.73871966513081 0.016372028937068458 0.1495974231996704 1.7424587780600926e-05 4.758837487360682 -0.21607318738060144 SAS(ph)PCIADK ddPTM_PC-9_AZD4547_30min_R2 1 SASPCIADK 9 0 Q05209-2;Q05209-3;Q05209 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 S(0.002)AS(0.998)PCIADK 91.469 0.007776899999999999 16223000.0 37573.0 40516.0 48049.0 54437.0 54758.0 53367.0 45566.0 52640.0 40308.0 46569.0 True False 49520.43243305018 53612.004666436995 47411.83886534112 41887.39069326605 47155.79689188177 50029.95305358576 49621.28572696153 44505.69754686241 42438.59858958708 44938.6334845004 1.1019567929258478 1.1930047825091987 1.0550351710559631 0.9321020121297915 1.0493375796161244 1.1132949352107333 1.1042010377123772 0.9903660635834127 0.9443678033562014 1.0 15.45566863457219 -1.5228787452812393 0.3238680434499663 1.0074183494581974 2.424451116102346 0.27501291020976126 0.06661418542437654 85.42365340686149 1.2182593418711136 0.06868767574241202 71.99153230276343 0.02999999999993771 1.5228787452812393 1.4170327666441485 SAS(ph)PCIADK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SASPCIADK 9 0 Q05209-2;Q05209-3;Q05209 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 S(0.014)AS(0.986)PCIADK;S(0.012)AS(0.988)PCIADK;S(0.001)AS(0.999)PCIADK 97.59700000000001 0.004732500000000001 21086100.0 134413.0 131616.0 129298.0 148228.0 153127.0 121174.0 137033.0 122572.0 104957.0 90171.0 True False 157166.46612223904 144681.96666015888 132380.9546853959 139923.26572165967 123122.86358136716 114819.42212536446 124052.24220699401 119354.61487576937 106491.79756586377 106518.28850675696 1.4754880905945953 1.3582828703728282 1.2428002415472377 1.3136079041749125 1.1558847340431768 1.077931533964526 1.1646097956138752 1.120508192057537 0.9997513014782292 1.0 16.70074162763749 -1.5228787452803376 0.216036443729551 0.9828333215155333 3.5596748024310805 0.8973583029847085 0.04745189132631657 15.416901926901026 0.1950984323874671 0.0786249151669203 13.77017752129768 0.029999999999999995 1.5228787452803376 2.5768414809155473 SAS(ph)PCIADK ddPTM_PC-9_Lapatinib_30min_R1 1 SASPCIADK 9 0 Q05209-2;Q05209-3;Q05209 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 S(0.052)AS(0.948)PCIADK 106.16 0.0025881 13826000.0 118290.0 131610.0 143590.0 173420.0 117790.0 117120.0 111470.0 103760.0 139190.0 91476.0 True False 116603.16290827094 131305.26513109438 131784.584473429 186173.88531216103 110861.82378405017 112111.05062005477 117241.37117310107 108581.06839450309 123512.9564643209 107287.50471589173 1.0868289202647412 1.2238635382452423 1.228331153962505 1.7352802248982162 1.0333153341353554 1.0449590650554907 1.0927774998921653 1.012056983541903 1.1512333779352575 1.0 16.71112253623366 SAS(ph)PDDDLGSSNWEAADLGNEER ddPTM_PC-9_AZD4547_30min_R2 1 SASPDDDLGSSNWEAADLGNEER 23 0 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 S(0.166)AS(0.834)PDDDLGSSNWEAADLGNEER 133.45 4.3514e-08 0.0 9458.9 8535.4 12828.0 15823.0 19526.0 13669.0 9257.5 14612.0 12391.0 11955.0 True False 12466.633442657721 11294.301131155751 12657.892338333706 12175.25181291306 16815.15194329383 12814.27526916378 10081.399565846164 12354.05115035626 13045.962963272137 11536.459088818794 1.0806291034950628 0.97900933416409 1.0972077516056735 1.0553716455956046 1.4575661226581367 1.1107632914490593 0.8738729525437418 1.07087027789401 1.130846376936955 1.0 13.493912861860755 -10.150937176418598 6.907423916592309 1.00001795489516 1.0945021160276003 0.03954695025574717 0.1406079845644413 0.0 0.0 0.14466829531068454 0.03508721542611768 7.06419735178961e-11 10.150937176418598 0.09448416113244029 SAS(ph)PDDDLGSSNWEAADLGNEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASPDDDLGSSNWEAADLGNEER 23 0 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 S(0.229)AS(0.771)PDDDLGSSNWEAADLGNEER 111.01 4.5799999999999995e-07 3937900.0 25531.0 28517.0 32679.0 28514.0 37814.0 28209.0 27334.0 32635.0 31133.0 25450.0 True False 29852.89403976459 31347.97929771261 33458.19129579764 26916.453023635295 30404.61815007027 26729.670380893607 24744.725638977336 31778.36582964072 31588.2612271506 30063.883537910864 0.9929819612998362 1.0427122383634333 1.112903170131248 0.8953085847905635 1.0113336858736077 0.8890957266777334 0.823071497325819 1.057027971438483 1.0507046166313636 1.0 14.875743762689218 -5.762452880025468 24.999999998829228 0.9566731338494725 1.0488504279181683 0.22229194730357216 0.07564486726209017 41.78712794732942 1030814.1716842402 0.022245623939328604 0.035260697476173 1.7280134559109088e-06 5.762452880025468 0.09217729406869579 SAS(ph)PDDDLGSSNWEAADLGNEER ddPTM_PC-9_Lapatinib_30min_R1 2 SASPDDDLGSSNWEAADLGNEER 23 0 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 S(0.186)AS(0.814)PDDDLGSSNWEAADLGNEER;S(0.212)AS(0.788)PDDDLGSSNWEAADLGNEER 162.02 1.2181e-08 12094800.0 50311.0 41947.0 58004.0 45957.0 51406.0 50902.0 41283.0 46362.0 57401.0 41915.0 True False 49593.55591409255 41849.87429871599 53235.135021914975 49336.831088057836 48382.40014808458 48725.040118357494 43420.43174072963 48516.14777280212 50935.89492067312 49159.95190177321 1.008820269254651 0.8513001473706987 1.082896401694705 1.0035980341607749 0.9841832279404533 0.9911531283780604 0.8832480517370777 0.9869038901775682 1.0361258087161769 1.0 15.585195883724076 -10.660712625753614 0.0044094828999528 1.704394463327585 0.28286728324939947 0.011254992677401376 0.0641030079603813 215018.56173418975 171.57144518900498 28425.376832600126 26898.118812261906 2.1841747101668235e-11 10.660712625753614 -1.4215271800781855 SAS(ph)PDDDLGSSNWEAADLGNEERK ddPTM_PC-9_AZD4547_30min_R2 2 SASPDDDLGSSNWEAADLGNEERK 24 1 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 S(0.05)AS(0.933)PDDDLGS(0.012)S(0.004)NWEAADLGNEERK;S(0.029)AS(0.518)PDDDLGS(0.226)S(0.226)NWEAADLGNEERK 150.13 7.3873999999999995e-09 73737000.0 70623.0 61401.0 82208.0 115239.0 101815.0 84422.0 73953.0 80321.0 70952.0 80732.0 True False 93079.64495034478 81247.67248800231 81117.86820624692 88672.42897480185 87679.7447048273 79143.07899431874 80534.67373405598 67909.2350429622 74702.37786862122 77905.59725290847 1.1947748073630207 1.0428990387461419 1.041232864731276 1.1382035707516691 1.1254614276325818 1.0158843752573128 1.033746952386651 0.8716862130265862 0.9588833216451894 1.0 16.249439364305218 -7.24526197100725 1.7289728802687196 0.9413568929280343 1.1009373471621535 0.5839973596722368 0.056960045243547426 0.25938574322255065 1.5145076590291198 0.0304495268011125 0.018995581166911368 5.6850989623391755e-08 7.24526197100725 0.15958045423411926 SAS(ph)PDDDLGSSNWEAADLGNEERK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SASPDDDLGSSNWEAADLGNEERK 24 1 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 S(0.062)AS(0.933)PDDDLGS(0.003)S(0.002)NWEAADLGNEERK;S(0.228)AS(0.763)PDDDLGS(0.005)S(0.005)NWEAADLGNEERK;S(0.038)AS(0.935)PDDDLGS(0.025)S(0.002)NWEAADLGNEERK;S(0.045)AS(0.955)PDDDLGSSNWEAADLGNEERK 146.72 2.1703000000000002e-09 68691800.0 88493.1 61271.0 65418.4 107066.0 117627.0 112542.0 101154.0 115673.0 99091.2 88868.6 True False 103473.2340116054 67353.57995406778 66978.22275666367 101067.43913265546 94578.83374248462 106640.0994011318 91571.96082845966 112636.70631567418 100540.22133786752 104979.77369654972 0.9856492385923877 0.6415862559273304 0.6380107367183722 0.9627324919255105 0.900924343920481 1.0158156723540037 0.8722819415971867 1.0729372178040437 0.9577104026579921 1.0 16.67975186710369 -5.780522921841755 24.563644268763813 0.9670486383701057 0.7437325351558262 0.4689529567907458 0.10405289747998277 154.8503306928373 199317.20498126143 0.028834453608233362 0.0428504721273678 1.6575898477914186e-06 5.780522921841755 -0.22331610321427953 SAS(ph)PDDDLGSSNWEAADLGNEERK ddPTM_PC-9_Lapatinib_30min_R1 2 SASPDDDLGSSNWEAADLGNEERK 24 1 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 S(0.021)AS(0.979)PDDDLGSSNWEAADLGNEERK;S(0.117)AS(0.69)PDDDLGS(0.143)S(0.049)NWEAADLGNEERK 177.82 7.6138e-15 62616000.0 117719.0 80876.0 84629.0 69486.0 72102.0 76163.0 62417.0 65880.0 74654.0 57037.0 True False 116040.30547297954 80688.73659100673 77671.13029738712 74596.23223850102 67861.10211798616 72905.68603462457 65648.64685127334 68941.02530676413 66245.68037852876 66895.76945297471 1.734643407525967 1.2061859404685968 1.1610768652864827 1.1151113567942357 1.0144303993048476 1.0898400097763223 0.9813572276408593 1.0305737697692103 0.9902820599903117 1.0 16.02962735600361 -1.658049287104361 0.8577289947608396 1.0265436451304397 199.99999760949797 0.9543356859418686 0.04562717534128952 98.92296437408548 0.344860037324178 0.015339989055768144 38314.36443481986 0.021976104567622376 1.658049287104361 198.97345396436754 SAS(ph)PDGGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASPDGGPR 9 0 O75420 O75420 GIGYF1 PERQ amino acid-rich with GYF domain-containing protein 1 1 S(0.029)AS(0.971)PDGGPR 76.843 0.023925 20361000.0 25017.0 35476.0 36555.0 30410.0 46385.0 47762.0 29882.0 27172.0 45722.0 31863.0 True False 29251.88399172734 38997.822827283824 37426.6098356095 28706.226290550218 37296.19222750861 45257.27663980434 27051.36063305482 26458.76379111377 46390.597752474205 37639.50967263078 0.7771590078124098 1.0360874295777749 0.9943437138561854 0.762662068135911 0.990878801341777 1.2023875186852593 0.7186958828192431 0.7029518721481384 1.2324973985037508 1.0 15.19996021384673 -7.616157669409893 0.00981032174083543 1.8876514679242162 6.120093021473346e-06 0.02782742921411252 0.18070197593165652 8839.253527855672 73.9823447069648 7059.995452804003 7164.562252101882 2.420150258370627e-08 7.616157669409893 -1.8876453478311948 SAS(ph)PDGGPR ddPTM_PC-9_Lapatinib_30min_R1 1 SASPDGGPR 9 0 O75420 O75420 GIGYF1 PERQ amino acid-rich with GYF domain-containing protein 1 1 S(0.312)AS(0.688)PDGGPR 72.289 0.032687 18215000.0 21757.0 27082.0 24252.0 27815.0 28705.0 24308.0 26996.0 25777.0 34644.0 26495.0 True False 21446.741190254863 27019.29329291311 22258.094175427246 29860.60788811995 27016.628336201353 23268.4035047156 28393.720787557508 26974.693523564987 30742.027902506925 31074.625447631643 0.6901689362723897 0.8694969900263879 0.716278759753278 0.960932190106117 0.869411230128292 0.7487911171746401 0.913726887405542 0.8680617428204872 0.9892968124206283 1.0 14.923449381668691 -1.5228787452807677 0.09041234791899984 1.1133170767253824 0.10853015546050329 0.46503036498410144 0.07720950934362339 148.2258550122467 0.9668113884012851 1.3984169126820314 18.468185506594452 0.029999999999970287 1.5228787452807677 -1.004786921264879 SAS(ph)PDYNR ddPTM_PC-9_AZD4547_30min_R2 4 SASPDYNR 8 0 Q14669;Q14669-2;Q14669-3;G5E9G6;F8W9P3;C9JLJ5;C9JSX9;C9JLD7 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 S(0.014)AS(0.974)PDY(0.012)NR;S(0.126)AS(0.863)PDY(0.01)NR;S(0.061)AS(0.794)PDY(0.145)NR;S(0.155)AS(0.844)PDY(0.001)NR 111.06 0.0037521 284280000.0 217641.0 227393.0 308707.0 370186.0 289004.0 240371.0 202447.0 322967.0 223558.0 265603.0 True False 286846.31078597566 300893.340337524 304613.3434744291 284845.3370166869 248880.78317216504 225340.56337143693 220464.39080819476 273059.87119334127 235374.81947729713 256304.3198132619 1.1191629973110324 1.1739690558346763 1.188483064570914 1.1113559741178745 0.9710362406435229 0.879191437489682 0.8601665042899808 1.065373659688167 0.9183412111383312 1.0 17.967498268792603 -6.219392276760823 3.0904010819778076 0.9417284654538113 1.1604263910916983 0.7475824768200485 0.05730103145452145 0.13056049551589566 2.5134723689737353 0.018705850379558346 0.024046935962713387 6.034033586964732e-07 6.219392276760823 0.21869792563788704 SAS(ph)PDYNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SASPDYNR 8 0 Q14669;Q14669-2;Q14669-3;G5E9G6;F8W9P3;C9JLJ5;C9JSX9;C9JLD7 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 S(0.002)AS(0.998)PDYNR;SAS(0.998)PDY(0.001)NR;S(0.047)AS(0.952)PDYNR 107.21 0.0038138000000000004 161308000.0 113842.0 118687.0 109102.0 123489.0 154676.0 131043.0 136026.0 136411.0 127817.0 100782.0 True False 133113.20211800892 130469.46098494272 111703.40545163932 116570.31168673985 124368.34815095676 124170.87439198275 123140.63253704262 132830.35578940145 129686.08181899303 119052.97881012673 1.11810055866226 1.0958941329223162 0.9382663631608161 0.9791465350283557 1.0446470923613538 1.0429883874641925 1.0343347454870082 1.1157247564653359 1.0893140441771276 1.0 16.8612441929941 -7.648194598492559 12.225559177244099 1.0768662617658515 1.0330217089228864 0.057493834534056876 0.055570201370577985 1.0632653772968763 109.32026842734524 0.027850789377532815 0.016071338940347627 2.2480470761180253e-08 7.648194598492559 -0.04384455284296518 SAS(ph)PDYNR ddPTM_PC-9_Lapatinib_30min_R1 4 SASPDYNR 8 0 Q14669;Q14669-2;Q14669-3;G5E9G6;F8W9P3;C9JLJ5;C9JSX9;C9JLD7 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 S(0.012)AS(0.988)PDYNR;S(0.024)AS(0.973)PDY(0.003)NR;S(0.287)AS(0.663)PDY(0.05)NR;S(0.36)AS(0.634)PDY(0.006)NR 106.88 0.003819 263375000.0 218429.0 260503.0 252406.0 171328.0 181881.0 231110.0 217842.0 209584.0 230548.0 161867.0 True False 215314.1624050269 259899.8213087572 231654.15299533634 183928.03265345373 171183.1171718044 221225.964043723 229120.79285090763 219322.03776400856 204581.2564619318 189845.49527578027 1.1341547087659332 1.3690070492913833 1.2202246498333946 0.9688301130678371 0.9016970190582302 1.165294776799195 1.206880324013345 1.155265956905688 1.0776197568698984 1.0 17.53446624099773 -5.597524431900345 7.479641408111567 1.0777986522032783 1.2621306822280745 0.36923633563803526 0.10349024726983878 0.2511760207862172 21.266517079566135 0.030413002805988798 0.052950057759648166 2.526245588324761e-06 5.597524431900345 0.18433203002479615 SAS(ph)PHDVDLCLVSPCEFEHR ddPTM_PC-9_AZD4547_30min_R2 2 SASPHDVDLCLVSPCEFEHR 20 0 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 S(0.197)AS(0.803)PHDVDLCLVSPCEFEHR;S(0.255)AS(0.745)PHDVDLCLVSPCEFEHR 138.77 9.4272e-06 25854000.0 49009.0 49737.0 89329.0 110663.0 100781.0 90481.0 67767.0 118615.0 92645.0 91602.0 True False 64592.84254947319 65813.51258995409 88144.4390934682 85151.35507630653 86789.29775668817 84823.20876649431 73798.1317179258 100285.77725154032 97542.02556148401 88395.0418614789 0.7307292489401681 0.7445385080883652 0.9971649680487351 0.9633046524232044 0.9818344550669817 0.9595923818828901 0.8348673202007478 1.1345181261262935 1.1034784701424665 1.0 16.431677829681277 -5.255573093600552 7.57975275431222 0.9929558141478046 0.736568675502509 0.6434247572972154 0.07714647553958905 0.08345848067564492 39.7047083167863 0.021352395114183246 0.05146033776426138 5.55171171596802e-06 5.255573093600552 -0.2563871386452956 SAS(ph)PHDVDLCLVSPCEFEHR ddPTM_PC-9_Lapatinib_30min_R1 1 SASPHDVDLCLVSPCEFEHR 20 0 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 S(0.338)AS(0.662)PHDVDLCLVSPCEFEHR 102.19 0.00013452 11918000.0 22686.0 34684.0 53980.0 39779.0 44965.0 43600.0 39562.0 45603.0 46524.0 28002.0 True False 22362.493479897126 34603.69132897862 49541.9727688258 42704.480358853965 42320.24710459132 41735.32963656409 41610.326781647294 47721.88186193638 41283.97720056092 32842.108389680376 0.6809091917778292 1.0536379369557092 1.50848941185496 1.300296553806897 1.2885971449351028 1.2707871596233493 1.2669809833135457 1.4530699824659101 1.2570440579123459 1.0 15.003259127423293 -4.9071917019341775 3.297164236878552 1.3076087618841914 0.6682289153615797 0.6794356266353294 0.12912353208333663 0.13910108818427688 2.663813042183232 0.030921144305546804 0.19172902168112974 1.238249889976912e-05 4.9071917019341775 -0.6393798465226117 SAS(ph)PSTQQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASPSTQQEK 10 0 P55198;Q6P2C6 P55198 MLLT6 Protein AF-17 1 S(0.036)AS(0.842)PS(0.103)T(0.019)QQEK 92.24700000000001 0.019212 0.0 10886.0 13360.0 9875.8 8165.4 21779.0 15905.0 7836.8 11683.0 14012.0 14557.0 True False 12728.784791699392 14686.292506835956 10111.27652618006 7707.919110583979 17511.561291859656 15070.913800847708 7094.44157048136 11376.333629161716 14216.898991900363 17196.068866851398 0.7402148066664515 0.8540494121389861 0.5879993040543944 0.4482372785469834 1.0183467760830167 0.8764162273099336 0.41256182592739016 0.6615659495927992 0.8267528527584619 1.0 14.06979117270289 -8.5543571263197 3.704825556577064 0.9994637052348551 0.7008393258812778 0.21601880789179317 0.1783533966261529 0.3660245627700751 14.889923523360865 0.1799856503702594 0.04733490424785494 2.7902484379671524e-09 8.5543571263197 -0.2986243793535772 SAS(ph)PSTQQEK ddPTM_PC-9_Lapatinib_30min_R1 2 SASPSTQQEK 10 0 P55198;Q6P2C6 P55198 MLLT6 Protein AF-17 1 S(0.002)AS(0.555)PS(0.36)T(0.083)QQEK;S(0.038)AS(0.794)PS(0.133)T(0.035)QQEK 116.74 0.0010155 5050800.0 7091.1 22143.0 18279.9 17998.3 27029.0 16783.4 33435.0 35133.0 25740.0 19183.6 True False 6989.979613651525 22091.729243961872 16776.99718445457 19321.955022568724 25439.207361058576 16065.61310601629 35166.10070128856 36765.407439322225 22840.89014578364 22499.45969945975 0.3106732209138056 0.9818782112573278 0.7456622251625631 0.8587741786098392 1.1306585891780065 0.7140443957595147 1.562975341231548 1.6340573476173308 1.0151750509072042 1.0 14.45760273662424 -6.165819914796736 0.6754150573397217 1.308457658020927 0.5732471028474537 0.4125478947946497 0.2845148164379497 0.8765456985450295 0.8276263842882794 0.1796471645634998 0.3785165160265022 6.82621692401351e-07 6.165819914796736 -0.7352105551734733 SAS(ph)PSVPGPTKPKPK ddPTM_PC-9_AZD4547_30min_R2 1 SASPSVPGPTKPKPK 15 2 Q03164-2;Q03164;Q03164-3;A0A3B3ITZ6 Q03164-2 KMT2A Histone-lysine N-methyltransferase 2A;MLL cleavage product N320;MLL cleavage product C180 1 S(0.031)AS(0.731)PS(0.238)VPGPTKPKPK 81.594 0.024350999999999998 34961000.0 44422.0 38560.0 57920.0 64824.0 65701.0 56333.0 45936.0 63873.0 54368.0 52200.0 True False 58547.27196500032 51023.76591810177 57151.942955744285 49879.8283208163 56579.55023181136 52810.488604711594 50024.21501017656 54002.895505523236 57241.78148552814 50372.4938884434 1.1622865465954704 1.0129291202278112 1.134586329640833 0.9902195517911386 1.1232231296134416 1.0483993252680215 0.9930859314006142 1.0720711113712147 1.1363698134997582 1.0 15.620348538606374 -4.7444014080208055 24.632212812970554 1.059194951210205 1.1622869159864655 0.2445427455637148 0.055492657529464 1283.671379593469 1855715.6660173838 0.013083172207471636 0.37098144521666093 1.8013520245184e-05 4.7444014080208055 0.10309196477626048 SAS(ph)PTVPR ddPTM_PC-9_AZD4547_30min_R2 3 SASPTVPR 8 0 Q92817;K7EKI0;K7EQ87 Q92817 EVPL Envoplakin 1 S(0.104)AS(0.885)PT(0.011)VPR;S(0.012)AS(0.803)PT(0.185)VPR;S(0.342)AS(0.522)PT(0.137)VPR 117.01 0.0035650999999999994 244099000.0 291903.0 312350.0 472780.0 578280.0 611050.0 472420.0 434130.0 560430.0 396170.0 458270.0 True False 384722.0820404178 413311.0291628391 466510.6282910354 444966.48033693805 526216.2549907655 442879.50271843874 472766.7289787519 473828.420900231 417110.7374029147 442226.106786532 0.8699669154225848 0.9346147204338379 1.0549142647433656 1.0061967701778605 1.189925802469135 1.0014775155104585 1.0690611018289842 1.0714618916177054 0.9432069500235525 1.0 18.754424671503415 -5.082282925509828 2.4232149290787963 1.049123792036647 0.8676186929204607 0.45633894852742574 0.06231682991555371 0.28358590299389863 2.9411589486293024 0.016342343052387447 0.08107517544308793 8.274029681108307e-06 5.082282925509828 -0.18150509911618629 SAS(ph)PTVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SASPTVPR 8 0 Q92817;K7EKI0;K7EQ87 Q92817 EVPL Envoplakin 1 S(0.066)AS(0.931)PT(0.003)VPR;S(0.001)AS(0.898)PT(0.101)VPR;S(0.017)AS(0.724)PT(0.259)VPR 99.68799999999999 0.0051229 334398000.0 176070.0 190842.0 267816.0 261620.0 308043.0 228143.0 247746.0 236423.0 232484.0 174576.0 True False 205875.17345898534 209787.5325291608 274201.74913783657 246962.27958348417 247684.18545517768 216178.7794572019 224277.70535428697 230217.14676087437 235883.63868348277 206225.24685714397 0.9983024707037876 1.0172737612213139 1.329622601095884 1.197536593347174 1.2010371631498304 1.0482653445771017 1.0875375773444862 1.1163383255414407 1.143815523454719 1.0 17.653861438015568 -6.765651361216163 24.999764377441412 1.0869841416645598 1.1542083729246426 0.11338996110064803 0.09542292126990695 287.9174465567987 1708892.937816099 0.035679736030603516 0.03259277730068473 1.7153337742352375e-07 6.765651361216163 0.06722423126008281 SAS(ph)PTVPR ddPTM_PC-9_Lapatinib_30min_R1 3 SASPTVPR 8 0 Q92817;K7EKI0;K7EQ87 Q92817 EVPL Envoplakin 1 S(0.006)AS(0.926)PT(0.068)VPR;S(0.005)AS(0.944)PT(0.051)VPR;S(0.012)AS(0.646)PT(0.342)VPR 131.62 0.0039774 247671000.0 479090.0 427340.0 506930.0 441800.0 378390.0 376530.0 380170.0 357100.0 407380.0 311585.0 True False 472258.0887456548 426350.52048569155 465252.1722063878 474291.445801595 356133.8441433626 360426.6896343 399853.34241390356 373692.16965764225 361496.5744984199 365442.05208908586 1.2922926796353742 1.166670661048493 1.2731216058653552 1.2978567821909404 0.974528908502697 0.98627590222276 1.094163466213322 1.0225757203403214 0.9892035479548364 1.0 18.47928313152657 -6.262188350709017 24.999998647693445 1.0151628814717026 1.2521155380232933 0.8731344025385913 0.04597170627621621 24.174270344324878 806917.2813979274 0.014460707591904008 0.01739460879845816 5.467787770441146e-07 6.262188350709017 0.2369526565515907 SAS(ph)QSSLDKLDQELK ddPTM_PC-9_AZD4547_30min_R2 2 SASQSSLDKLDQELK 15 1 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 S(0.023)AS(0.97)QS(0.006)S(0.001)LDKLDQELK;S(0.193)AS(0.79)QS(0.01)S(0.006)LDKLDQELK 171.98 0.00053582 21706500.0 43236.0 45727.0 45394.0 44919.0 38004.0 51023.0 50753.0 46914.0 43047.0 46150.0 True False 56984.148635332785 60507.358509778 44792.0459000873 34563.61854163193 32727.80059679086 47832.523744132246 55269.91867841109 39664.51927647232 45322.37653780775 44534.302546966755 1.279556327961714 1.35866860036633 1.005787524186524 0.776112267732956 0.7348897080464093 1.0740602413990232 1.241063978045291 0.8906509591037455 1.0176958871200437 1.0 15.442629379682264 -5.307018349699659 5.543097398667317 0.960194512553593 1.3198190762095618 0.5098748416595988 0.13804008510349625 0.15762438133628884 12.150454259444517 0.040194760775763415 0.08838487169244107 4.931529669413854e-06 5.307018349699659 0.35962456365596884 SAS(ph)QSSLDKLDQELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SASQSSLDKLDQELK 15 1 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 S(0.117)AS(0.874)QS(0.005)S(0.004)LDKLDQELK;S(0.01)AS(0.968)QS(0.016)S(0.007)LDKLDQELK 100.58 0.0067174999999999995 6972300.0 22300.4 29178.0 23168.5 32803.0 33034.0 26734.0 42028.0 32650.0 29303.0 26243.0 True False 26075.41726702307 32074.59900931583 23720.924907025536 30965.15425876089 26561.224836553167 25332.021977482727 38046.803583629895 31792.97209553454 29731.500939170455 31000.64816052631 0.8411249059052053 1.0346428514406676 0.7651751274423294 0.9988550593658033 0.8567957901723505 0.8171449140775854 1.2272905839457764 1.0255583022298582 0.9590606230300732 1.0 14.920010759184493 -7.237368989500891 24.998609406755705 1.0551072826635894 0.890758398758567 0.40140226694252734 0.09998835258595708 795.2578405937495 825926.2038640514 0.03711860699943316 0.02873750678820816 5.789366056604022e-08 7.237368989500891 -0.16434888390502245 SAS(ph)QSSLDKLDQELK ddPTM_PC-9_Lapatinib_30min_R1 3 SASQSSLDKLDQELK 15 1 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 S(0.065)AS(0.924)QS(0.01)S(0.002)LDKLDQELK;S(0.018)AS(0.975)QS(0.006)S(0.002)LDKLDQELK;S(0.02)AS(0.851)QS(0.091)S(0.038)LDKLDQELK 152.71 0.00073305 43130700.0 57533.0 82312.0 69455.0 75082.0 96447.0 111775.0 122833.0 108433.0 101980.0 100113.0 True False 56712.56886973999 82121.41162123426 63744.678004053225 80603.78074620976 90774.17708209774 106994.6438102511 129192.69171351499 113471.19303412795 90493.93850299196 117417.39865781294 0.48299970462653696 0.6993973002294062 0.542889543906717 0.6864722065689061 0.7730896623475625 0.9112333013105097 1.100285759949584 0.9663916449453515 0.7707029753462393 1.0 16.841286674175663 -6.450949077968639 1.6432360385184261 0.9613650637171205 0.5901709162313479 0.756714568235654 0.09371227179055097 0.18637071463619376 1.0123075634910665 0.03644638154061696 0.04225703204386894 3.540388505230139e-07 6.450949077968639 -0.3711941474857726 SAS(ph)SDTSEELNSQDSPPK ddPTM_PC-9_AZD4547_30min_R2 1 SASSDTSEELNSQDSPPK 18 0 J3QRP6;O14745;O14745-2 J3QRP6 SLC9A3R1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 1 S(0.045)AS(0.472)S(0.472)DT(0.012)SEELNSQDSPPK 267.6 2.8985e-78 26586000.0 33242.0 37282.0 29820.0 29318.0 33292.0 34242.0 34719.0 35223.0 38284.0 26635.0 True False 43812.26452344648 49332.67741075386 29424.56731595813 22559.18805858467 28669.980461750387 32100.84232692269 37808.923740384904 29780.09469401853 40307.61408166495 25702.516757063026 1.7045904468248976 1.9193714715582197 1.1448126887368837 0.8777034666220158 1.1154542075678993 1.2489377063863372 1.47102029337244 1.1586450842731186 1.5682360783049956 1.0 14.649622012710276 -5.264361696997782 24.99652614913724 1.2009353208599802 1.8119809885635856 0.6070100534601488 0.19756632748820233 159.8028369104186 1366912.5409632204 0.053597127768230585 0.12001619032799099 5.440493590656347e-06 5.264361696997782 0.6110456677036054 SAS(ph)SDTSEELNSQDSPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASSDTSEELNSQDSPPK 18 0 J3QRP6;O14745;O14745-2 J3QRP6 SLC9A3R1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 1 S(0.025)AS(0.755)S(0.154)DT(0.033)S(0.033)EELNSQDSPPK 90.725 0.0013102 4307400.0 13729.0 20803.0 12138.0 14658.0 13140.0 14260.0 14012.0 8764.3 7172.0 9156.9 True False 16053.048539889855 22868.184357762588 12427.415953621346 13836.759781877185 10565.311326279245 13512.180496704706 12684.681921904967 8534.246411543441 7276.876931909039 10816.973484019483 1.484061005012716 2.114101915064045 1.1488810591965544 1.2791710918325723 0.9767345128365127 1.2491646130654754 1.1726646035182349 0.7889680439867546 0.6727276296516372 1.0 13.401009278864322 -5.475720750246969 0.5550450584347103 0.8828918938338347 2.044632438740676 0.5850591041324733 0.2464563554071453 1.4385122699073987 0.5741045662927443 0.1578700758608662 0.9862319665118428 3.3440999530685e-06 5.475720750246969 1.161740544906841 SAS(ph)SDTSEELNSQDSPPK ddPTM_PC-9_Lapatinib_30min_R1 1 SASSDTSEELNSQDSPPK 18 0 J3QRP6;O14745;O14745-2 J3QRP6 SLC9A3R1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 1 S(0.009)AS(0.442)S(0.442)DT(0.107)S(0.001)EELNSQDSPPK 177.44 1.6938e-08 25101000.0 23049.0 57323.0 47102.0 46559.0 59665.0 63168.0 68352.0 88289.0 57301.0 56978.0 True False 22720.317033331063 57190.27211541463 43229.45537897796 49983.10417627095 56155.62200590331 60466.45189180003 71890.93211109545 92391.22925484096 50847.15797371982 66826.57138158742 0.33998926719725653 0.8558013815919358 0.6468902187444691 0.7479525455654707 0.8403187660975189 0.9048264880526284 1.0757836385259083 1.382552289377176 0.7608823395020028 1.0 16.028134236413905 -6.41746513389288 0.8774326510161905 1.084834972084903 0.5970689219472259 0.4990189437955356 0.18452300069885622 0.4965567617127 0.8348335870521862 0.097712152796857 0.1334096716208393 3.824149535313324e-07 6.41746513389288 -0.48776605013767715 SAS(ph)SGAEGDVSSER ddPTM_PC-9_AZD4547_30min_R2 1 SASSGAEGDVSSER 14 0 Q8TEA8 Q8TEA8 DTD1 D-tyrosyl-tRNA(Tyr) deacylase 1 1 SAS(0.977)S(0.023)GAEGDVSSER 104.41 0.0010692 7372400.0 9825.9 11584.0 11565.0 12113.0 14029.0 15122.0 15421.0 15555.0 14258.0 9892.3 True False 12950.3318085835 15328.301462533476 11411.640543563239 9320.534993984447 12081.315508167003 14176.418949469216 16793.439125564535 13151.332168340516 15011.648771716089 9545.97358798178 1.3566276597378972 1.6057347447337953 1.1954401966846318 0.9763839076318883 1.2655928069376994 1.4850678999695839 1.759217011317441 1.377683695343325 1.5725634094164582 1.0 13.220676629376065 -6.76285618177582 24.902915373576345 1.4825310793656015 1.2764942458905122 0.09026669159332057 0.23239450700814238 72.74571302936063 1278617.869779762 0.0813436880747994 0.07565348029481136 1.7264095042327083e-07 6.76285618177582 -0.20603683347508928 SAS(ph)SGAEGDVSSER ddPTM_PC-9_Lapatinib_30min_R1 2 SASSGAEGDVSSER 14 0 Q8TEA8 Q8TEA8 DTD1 D-tyrosyl-tRNA(Tyr) deacylase 1 1 S(0.007)AS(0.831)S(0.162)GAEGDVSSER;SAS(0.614)S(0.386)GAEGDVSSER 140.33 2.3341e-05 19303400.0 18640.0 25196.7 23351.0 20465.5 23391.0 26938.0 24460.9 22241.5 22997.4 21763.4 True False 18374.190181842656 25138.35858923062 21431.17091746666 21970.601140906652 22015.187368475377 25785.924535545044 25727.365713897096 23274.921286587676 20407.190638641976 25525.17469209235 0.719845815101706 0.984845702036211 0.8396091770571112 0.8607424398044611 0.862489194845575 1.0102153989776013 1.0079212394917472 0.9118418019602507 0.7994926924031625 1.0 14.639633214366645 -6.673612342949243 11.42730096867379 0.9442288449433301 0.8602563148590894 0.23369917550856334 0.08317783519725921 0.805254126902511 99.7534779238042 0.027456695139564984 0.02744970081480091 2.1202528568324028e-07 6.673612342949243 -0.08397253008424077 SAS(ph)SGAEGDVSSEREP ddPTM_PC-9_Lapatinib_30min_R1 1 SASSGAEGDVSSEREP 16 1 Q8TEA8 Q8TEA8 DTD1 D-tyrosyl-tRNA(Tyr) deacylase 1 1 S(0.025)AS(0.881)S(0.094)GAEGDVSSEREP 172.43 9.0368e-05 201150000.0 36676.0 27679.0 29822.0 28403.0 39911.0 29624.0 29737.0 33073.0 33678.0 26478.0 True False 36152.99351444534 27614.910976092684 27370.150276249013 30491.85136963043 37563.51344804504 28357.050576916863 31276.63635574154 34609.69231892249 29884.828994937878 31054.687020282738 1.1641718846122244 0.8892348829037164 0.8813532803719051 0.981875983799653 1.2095924014146786 0.9131327119283486 1.0071470478937314 1.1144756440893406 0.9623290994824456 1.0 14.922523407435136 -6.019223632170236 24.878142087987662 1.0384661086253701 0.9630620015933791 0.05549066922798307 0.10564063174634615 1741.8908915046047 2254258.91327203 0.030674668815029643 0.0402656244072632 9.5670130822082e-07 6.019223632170236 -0.07540410703199107 SAS(ph)SSWLEGTSTQAK ddPTM_PC-9_AZD4547_30min_R2 3 SASSSWLEGTSTQAK 15 0 Q9BZL4-3;K7EL81;Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-3;Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 S(0.047)AS(0.43)S(0.279)S(0.245)WLEGTSTQAK;SAS(0.499)S(0.499)S(0.001)WLEGTSTQAK;SAS(0.481)S(0.481)S(0.039)WLEGTSTQAK 217.48 7.7458e-18 44140000.0 70884.0 91554.0 133412.0 172254.0 152492.0 153370.0 120291.0 162332.0 127214.0 132742.0 True False 93423.63752120745 121147.04006394945 131642.86971014758 132543.50159777084 131321.11800352146 143779.7496548134 130996.66596545489 137247.3194182611 133938.27232747155 128094.7429835201 0.7293323312513049 0.9457612173790418 1.0276992376422813 1.0347302200748636 1.0251874116365294 1.1224484807570225 1.0226545048949287 1.0714516163705368 1.0456188068912653 1.0 16.966851743034148 -4.371004674858774 1.230823951486805 1.0518522764490819 0.22772878991750992 0.9023148494751971 0.0314791659217324 0.9289633587171674 0.6151356513558208 0.008965081324531303 1.2443704032173257 4.255938319063719e-05 4.371004674858774 -0.824123486531572 SAS(ph)SSWLEGTSTQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SASSSWLEGTSTQAK 15 0 Q9BZL4-3;K7EL81;Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-3;Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 SAS(0.499)S(0.499)S(0.002)WLEGTSTQAK;SAS(0.497)S(0.497)S(0.006)WLEGTSTQAK;S(0.001)AS(0.996)S(0.002)S(0.001)WLEGTSTQAK 233.62 8.450100000000001e-32 35593600.0 99948.0 100182.0 118496.0 127742.0 140192.0 113143.0 108427.0 98951.0 87461.0 97544.0 True False 116867.22233701711 110127.40688022741 121321.39403858235 120585.02988515192 112722.38397669276 107209.58190313194 98156.00961649958 96353.6410972508 88739.95166504393 115227.9550421211 1.0142262985947879 0.9557351498598651 1.0528816032032662 1.0464911040126725 0.9782555277969444 0.9304129528632347 0.8518419821007763 0.8362002177512317 0.7701251977665091 1.0 16.814131240765725 -6.939678114333061 1.9774871520912458 0.849962009979681 1.0144724465836608 0.5668402248682888 0.05969521580176057 0.22344883785801412 1.7740589357907839 0.025226981037465603 0.020411166900779553 1.1490049129637234e-07 6.939678114333061 0.1645104366039798 SAS(ph)SSWLEGTSTQAK ddPTM_PC-9_Lapatinib_30min_R1 2 SASSSWLEGTSTQAK 15 0 Q9BZL4-3;K7EL81;Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-3;Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 SAS(0.333)S(0.333)S(0.333)WLEGTSTQAK;S(0.021)AS(0.469)S(0.469)S(0.04)WLEGTSTQAK 261.61 8.252799999999999e-51 29817000.0 98582.0 73884.0 91530.0 66472.0 75170.0 71623.0 62351.0 72707.0 82210.0 67348.0 True False 97176.2026022752 73712.92613741952 84004.7567160173 71360.57262409174 70748.64838990613 68559.85125136771 65579.22969421401 76085.23264995292 72950.64409032134 78989.01206443101 1.2302496266570466 0.9332048117944834 1.063499270601017 0.9034240429021092 0.8956770890133017 0.8679669419772427 0.8302323067507327 0.9632381854312915 0.9235543296935503 1.0 16.269364357615345 -1.5228787454817356 0.8986332231954596 0.910562059445977 150.005833559899 0.6513103354668364 0.0646966319411554 542.8498255628193 1.210561330442792 0.021495123634764666 165961.93521998735 0.029999999986087916 1.5228787454817356 149.09527150045304 SAS(ph)TAGDIACAFRPVK ddPTM_PC-9_AZD4547_30min_R2 1 SASTAGDIACAFRPVK 16 1 B7ZM87;O75044 B7ZM87 SRGAP2 SLIT-ROBO Rho GTPase-activating protein 2 1 S(0.084)AS(0.715)T(0.201)AGDIACAFRPVK 64.331 0.014337 11591000.0 16055.0 21827.0 20662.0 35263.0 18363.0 17396.0 21700.0 27265.0 23254.0 24268.0 True False 21160.156035254593 28882.15089975122 20388.008379689025 27133.660157919054 15813.614418452555 16308.225369988533 23631.25796152977 23051.82073737091 24483.1589660181 23418.384706604305 0.9035702632934858 1.23331097603867 0.8705984052751224 1.1586478101654463 0.6752649517279857 0.6963855780108262 1.0090900058903478 0.9843471710869102 1.0454674510114061 1.0 14.515353948294681 -6.230207148778968 24.999161776359585 0.8960742953163606 1.0430208125610487 0.1622362839485546 0.15526487771484004 1300.4643532360458 1040928.5371882158 0.0472807012221363 0.06103298491610447 5.88562857041391e-07 6.230207148778968 0.1469465172446881 SAS(ph)TAGDIACAFRPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASTAGDIACAFRPVK 16 1 B7ZM87;O75044 B7ZM87 SRGAP2 SLIT-ROBO Rho GTPase-activating protein 2 1 S(0.365)AS(0.542)T(0.093)AGDIACAFRPVK 54.355 0.033 5700600.0 30658.0 20214.0 29762.0 31272.0 35348.0 36694.0 37449.0 32211.0 24927.0 32349.0 True False 35847.79387689878 22220.71233032798 30471.63895301353 29519.931225191922 28421.813147741163 34769.702043904785 33901.55961271903 31365.49538037558 25291.51021774911 38213.61762545689 0.9380895111332757 0.5814867503024663 0.797402623632109 0.7724976869378243 0.7437613843921259 0.90987726900638 0.8871591259691339 0.8207936680530535 0.6618454830850817 1.0 15.22179922147034 -6.739942625211585 24.9841095462017 0.8466862283324369 0.7583944727727326 0.1289036242488394 0.11379548654161806 512.6483322703266 595812.3410629474 0.036467078582112455 0.03643536396051272 1.8199412757759449e-07 6.739942625211585 -0.08829175555970425 SAS(ph)TDLGTADVVLGR ddPTM_PC-9_AZD4547_30min_R2 4 SASTDLGTADVVLGR 15 0 Q9Y2K5-2;H7C0E9;A0A0U1RRA6;B5MCU0;B5MCG9;Q9Y2K5;Q9Y2K5-3 Q9Y2K5-2 R3HDM2 R3H domain-containing protein 2 1 S(0.001)AS(0.499)T(0.499)DLGTADVVLGR;S(0.047)AS(0.906)T(0.047)DLGTADVVLGR;S(0.021)AS(0.968)T(0.011)DLGTADVVLGR;S(0.053)AS(0.939)T(0.008)DLGT(0.001)ADVVLGR 173.33 1.0872e-05 33325700.0 57989.6 58346.1 74117.0 113495.0 113419.0 93432.0 67306.6 90005.0 75141.8 74868.0 True False 76429.08654138887 77205.33580482776 73134.16015281255 87330.48123027048 97672.72960444771 87589.6822699911 73296.75700983887 76096.79535914441 79113.64214297498 72246.89410804564 1.057887504853686 1.0686319011771874 1.0122810268278106 1.2087783469233604 1.3519298069530516 1.212366058795555 1.0145315991054666 1.0532881212213943 1.0950455811243605 1.0 16.140647947076474 -7.270856474693335 24.594098629077198 1.0451569992778869 1.1535111377637977 0.25242499065851487 0.09365612904539734 967.3693888985858 2526411.3988519376 0.044948991040524994 0.030757978999003448 5.3597375644315514e-08 7.270856474693335 0.1083541384859108 SAS(ph)TDLGTADVVLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SASTDLGTADVVLGR 15 0 Q9Y2K5-2;H7C0E9;A0A0U1RRA6;B5MCU0;B5MCG9;Q9Y2K5;Q9Y2K5-3 Q9Y2K5-2 R3HDM2 R3H domain-containing protein 2 1 S(0.122)AS(0.867)T(0.01)DLGTADVVLGR;S(0.008)AS(0.496)T(0.496)DLGTADVVLGR;SAS(0.996)T(0.003)DLGTADVVLGR 172.09 0.00010815 27866200.0 48464.0 50675.0 44194.0 59590.0 46276.0 53868.0 45878.0 41059.0 42532.0 41154.0 True False 56667.997992368124 55705.67910059218 45247.75256667831 56251.36549338662 37208.54999504556 51043.06725080566 41532.103712043696 39981.24475560654 43153.9500373613 48614.89442511528 1.165650952500937 1.145856218743811 0.9307384722675147 1.1570808937996215 0.7653734608507757 1.0499470965514623 0.8543082156851812 0.822407314227377 0.8876693150868438 1.0 15.569110767890711 -5.29375207598842 0.6504316921222384 0.8869972537046411 1.2580783490979686 0.4300092848919026 0.10575906661013554 1.7350949894242034 0.8611211915799392 0.051647123705775046 0.43578230915327304 5.084496163939416e-06 5.29375207598842 0.37108109539332745 SAS(ph)TDLGTADVVLGR ddPTM_PC-9_Lapatinib_30min_R1 2 SASTDLGTADVVLGR 15 0 Q9Y2K5-2;H7C0E9;A0A0U1RRA6;B5MCU0;B5MCG9;Q9Y2K5;Q9Y2K5-3 Q9Y2K5-2 R3HDM2 R3H domain-containing protein 2 1 S(0.011)AS(0.971)T(0.017)DLGTADVVLGR;S(0.126)AS(0.676)T(0.197)DLGTADVVLGR 193.98 1.436e-09 8541000.0 28933.0 18036.9 31404.0 27466.0 25377.2 27380.0 27216.0 26737.0 27007.3 53702.0 True False 28520.410114337625 17995.136666233833 28822.08434294563 29485.941263890054 23884.562989494832 26209.021225897373 28625.11131108924 27979.298628217282 23965.453474523 62984.31914658294 0.4528176298605735 0.28570820340780195 0.4576073018407678 0.46814733672467973 0.3792144348485925 0.41611978316223935 0.45447996737839197 0.44422642027932807 0.3804987304657272 1.0 15.942705073156445 -11.491462980658104 2.5720555040316624 1.4853830735174185 0.41535184745338327 0.917458482533569 0.052602320180735136 9957441.095649594 4791053.550214733 28792006.575924676 0.013375778191880511 3.225054211817276e-12 11.491462980658104 -1.0700312260640352 SAS(ph)TEKLEQGTSALIR ddPTM_PC-9_AZD4547_30min_R2 1 SASTEKLEQGTSALIR 16 1 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 1 S(0.002)AS(0.507)T(0.476)EKLEQGT(0.013)S(0.001)ALIR 102.36 0.0072976 11349000.0 18514.0 9936.0 16647.0 25491.0 27691.0 20274.0 16042.0 14845.0 16393.0 21012.0 True False 24401.06688487722 13147.617690929961 16426.249903043423 19614.443782024064 23846.582631452886 19006.263575025718 17469.70692252814 12551.046354163616 17259.50051302721 20276.37627555504 1.2034234595604174 0.6484204826471174 0.8101176304785148 0.9673544974439542 1.1760771405787158 0.9373599758029467 0.8615793416493959 0.6189984928073666 0.8512122816459596 1.0 14.307512221416479 -7.43424569141092 4.439926641233266 0.7914529338678662 0.945616554374391 0.09897185789977925 0.17447428259825754 0.48162357008137935 16.607280376029586 0.07923706688165984 0.051099381103243385 3.679207726367815e-08 7.43424569141092 0.15416362050652477 SAS(ph)TEKLEQGTSALIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASTEKLEQGTSALIR 16 1 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 1 S(0.002)AS(0.739)T(0.259)EKLEQGTSALIR 128.59 9.861100000000001e-05 7926200.0 9820.0 8650.5 12721.0 14322.0 17937.0 20260.0 15662.0 18661.0 19697.0 12985.0 True False 11482.33204615911 9509.26447083715 13024.316884661157 13519.584772550486 14422.37361183187 19197.52993430837 14178.381976939443 18171.168522963864 19985.03136193701 15339.077710796557 0.7485673038918866 0.6199371728942975 0.8490938718886513 0.8813818553793881 0.9402373391511372 1.2515439517459388 0.9243308003426994 1.1846324052569284 1.302883506996666 1.0 13.904924120404567 -6.073397159471734 0.911324030194068 1.144530940911417 0.6702022066552572 0.6809371584169692 0.11768337000763425 0.3551183391243659 0.6075174004197815 0.053690189165740095 0.10996498240340954 8.445061965132432e-07 6.073397159471734 -0.47432873425615985 SAS(ph)TEKLEQGTSALIR ddPTM_PC-9_Lapatinib_30min_R1 1 SASTEKLEQGTSALIR 16 1 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 1 S(0.004)AS(0.974)T(0.022)EKLEQGTSALIR 111.33 0.0022758 8981000.0 35465.0 22711.0 23903.0 19151.0 23743.0 17148.0 13648.0 16146.0 23071.0 18966.0 True False 34959.26259651554 22658.414074859695 21937.787608248294 20559.428425863207 22346.48342053402 16414.620013940395 14354.626659823132 16896.202103870903 20472.501031599626 22244.247829393527 1.5716091128206369 1.0186190267543633 0.9862229452083213 0.9242581985036149 1.0045960462194365 0.7379265030598218 0.6453185906720093 0.75957623892071 0.9203503390457323 1.0 14.441144695363647 -1.522878747152358 0.765443908228413 0.8252451757204212 142.76736141537256 0.773252723955434 0.11398907464566084 194.10082875015044 0.7845073565230261 0.04428697664983887 47597.20699898586 0.029999999870685416 1.522878747152358 141.94211623965214 SAS(ph)TLCLPSVGAARPQVK ddPTM_PC-9_AZD4547_30min_R2 2 SASTLCLPSVGAARPQVK 18 1 Q8IUC4-2;A8MT19;Q8IUC4 Q8IUC4-2 RHPN2;RHPN2P1 Rhophilin-2;Putative rhophilin-2-like protein RHPN2P1 1 S(0.002)AS(0.951)T(0.047)LCLPSVGAARPQVK;S(0.041)AS(0.805)T(0.154)LCLPSVGAARPQVK 152.86 1.4008e-05 162281000.0 71940.0 80840.0 115916.0 142415.0 150657.0 115968.0 122649.0 149472.0 107938.0 133208.0 True False 94815.42355504306 106969.94908763861 114378.87810183105 109583.42203981629 129740.87607911593 108716.5026274331 133564.52339740377 126374.53692485987 113643.38232020562 128544.42846535952 0.7376081926459703 0.8321632478724283 0.8898003551562265 0.8524945293085737 1.009307658278467 0.8457504064964613 1.0390533840476568 0.9831195208815728 0.8840786308434249 1.0 16.971907554856607 -3.274426307636155 0.4206169871828641 0.9715223895719319 2.627055583747554e-11 0.5902902982505078 0.058729282425516366 12.53428173498974 0.6375861775736021 0.03993766632375537 7.968955748109398 0.0005315861929615514 3.274426307636155 -0.9715223895456614 SAS(ph)TLCLPSVGAARPQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SASTLCLPSVGAARPQVK 18 1 Q8IUC4-2;A8MT19;Q8IUC4 Q8IUC4-2 RHPN2;RHPN2P1 Rhophilin-2;Putative rhophilin-2-like protein RHPN2P1 1 S(0.019)AS(0.832)T(0.149)LCLPSVGAARPQVK;S(0.074)AS(0.765)T(0.161)LCLPSVGAARPQVK 102.98 0.00020318 140379000.0 94626.0 101852.0 117565.0 147849.0 136220.0 122197.0 137144.0 129465.0 108168.0 105107.0 True False 110644.31285130898 111963.19344358187 120368.19546774549 139565.499862925 109528.6688634521 115788.77420447567 124152.72748342372 126066.68092950653 109749.75236624877 124162.06707344556 0.8911281477446696 0.901750398351151 0.9694441974499677 1.124059087872368 0.882142762641529 0.932561586108124 0.9999247790388645 1.0153397402359154 0.8839233668792621 1.0 16.92186495553281 -5.2640587300549 5.3797445660121985 0.9779654186068469 0.8952575591043723 0.18786106187413865 0.06622328042531823 0.26432416973032546 27.882818998509826 0.017475317104627654 0.04225468576132343 5.444290242105325e-06 5.2640587300549 -0.08270785950247461 SAS(ph)TLCLPSVGAARPQVK ddPTM_PC-9_Lapatinib_30min_R1 3 SASTLCLPSVGAARPQVK 18 1 Q8IUC4-2;A8MT19;Q8IUC4 Q8IUC4-2 RHPN2;RHPN2P1 Rhophilin-2;Putative rhophilin-2-like protein RHPN2P1 1 S(0.022)AS(0.489)T(0.489)LCLPSVGAARPQVK;S(0.043)AS(0.794)T(0.163)LCLPSVGAARPQVK;S(0.006)AS(0.661)T(0.212)LCLPS(0.121)VGAARPQVK 112.57 0.00045928 172262000.0 118406.0 146580.0 165671.0 156015.0 151261.0 146063.0 99717.0 115311.0 134340.0 109487.0 True False 116717.50872699899 146240.6030158485 152050.1698885536 167488.8635507828 142364.1253705679 139816.22597948325 104879.85834097168 120668.77002350173 119209.2145370852 128411.68206774273 0.9089321691575183 1.1388418924276704 1.1840836241701167 1.3043117328096765 1.1086540031105943 1.0888123551385622 0.8167470174998799 0.9397024326793236 0.9283362122318214 1.0 16.970416929969907 -7.098266078459364 5.068935855436331 0.9170522038701535 1.1387680279178107 0.49103720780245586 0.10053897514629988 0.1939634630393958 7.8046246772626455 0.04063893236685332 0.03146505508043643 7.975059309622628e-08 7.098266078459364 0.22171582404765722 SAS(ph)VNKEPVSLPGIMR ddPTM_PC-9_AZD4547_30min_R2 3 SASVNKEPVSLPGIMR 16 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.019)AS(0.98)VNKEPVS(0.001)LPGIMR;S(0.006)AS(0.994)VNKEPVSLPGIMR;S(0.134)AS(0.866)VNKEPVSLPGIMR 140.46 0.00010182 33164400.0 87440.0 78395.0 105693.0 129257.0 124404.0 100230.0 104920.0 117217.0 105641.0 113024.0 True False 115244.10113501461 103734.65065221966 104291.4417614205 99458.7956507429 107132.65196934988 93962.60225534331 114257.67674302794 99103.8060286965 111224.96758962411 109067.06416182799 1.0566352181628493 0.9511088562749211 0.9562138906267645 0.9119049496296256 0.9822640115295674 0.8615121620577091 1.0475910177017178 0.9086501666685689 1.0197851060205887 1.0 16.73485597991023 -8.296403303412097 24.652351127493347 1.0098925925600641 0.9579411787046258 0.11083443261437331 0.05697551496956254 1262.4613053968826 890123.6702521184 0.051397203255666025 0.013273442364179997 5.053551508114713e-09 8.296403303412097 -0.05195141385543833 SAS(ph)VNKEPVSLPGIMR ddPTM_PC-9_Lapatinib_30min_R1 1 SASVNKEPVSLPGIMR 16 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.014)AS(0.985)VNKEPVS(0.002)LPGIMR 132.64 2.8275999999999998e-05 8623800.0 10123.0 13120.0 13465.0 12654.0 18525.0 16668.0 21651.0 22025.0 19035.0 25886.0 True False 9978.644163669162 13089.621446090392 12357.959676403094 13584.617372506556 17435.395921551313 15955.148495005738 22771.98284084339 23048.361906215574 16891.077852563758 30360.36060907313 0.328673440087107 0.43114183044909504 0.40704258541349286 0.4474458504437797 0.5742815820290613 0.5255256582900262 0.7500564019663861 0.7591596886147531 0.5563530048294583 1.0 14.889901306199793 -7.254588053512219 0.14385268968166026 1.218550655867795 7.084801946516682e-21 0.8385970891433461 0.07766812908776656 2.8648627077902673 0.26936966225798986 0.7990040288937422 1.2181041997524564 5.5643180587991235e-08 7.254588053512219 -1.218550655867795 down SAS(ph)VSSISLTK ddPTM_PC-9_AZD4547_30min_R2 2 SASVSSISLTK 11 0 G5E9C8;Q07889 G5E9C8 SOS1 Son of sevenless homolog 1 1 S(0.008)AS(0.99)VS(0.001)SISLTK;S(0.026)AS(0.966)VS(0.008)SISLTK 129.34 0.00026431 30799200.0 210471.0 227018.0 289697.0 340129.0 302778.0 295888.0 234474.0 284626.0 250494.0 235540.0 True False 277396.3999312401 300397.12892104837 285855.4284953425 261717.5139906661 260742.5010287119 277386.0765851442 255341.7317636746 240643.59175481152 263734.6014463635 227293.81629279623 1.2204309138525025 1.321624731462477 1.2576471861738119 1.1514502165493399 1.1471605575614412 1.2203854953441406 1.1233993776352784 1.058733562046485 1.1603245778874374 1.0 17.794198909472158 -4.389723252310907 0.11948533067439876 0.9137643942253781 1.6607335124249356 0.6967467209527446 0.04925913096138453 24.88455910723085 0.43289620061742945 0.49432560962943106 3.0770010212460366 4.076399575473094e-05 4.389723252310907 0.7469691181995575 SAS(ph)VSSISLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASVSSISLTK 11 0 G5E9C8;Q07889 G5E9C8 SOS1 Son of sevenless homolog 1 1 S(0.002)AS(0.886)VS(0.081)S(0.023)IS(0.008)LT(0.001)K 73.082 0.025626999999999997 9305200.0 16922.0 20523.0 15323.0 20168.0 31500.0 38300.0 49543.0 51431.0 41005.0 27605.0 True False 19786.56037526521 22560.387808218125 15688.3584328011 19038.052345538203 25327.80112464202 36291.4805767034 44849.9283797415 50080.99074564894 41604.62055116146 32609.567978940246 0.6067716195456399 0.6918333853054406 0.4810967886153193 0.5838179873414228 0.776698456753524 1.1129089658636688 1.3753610108758958 1.5357759654464604 1.275840899763847 1.0 14.9930077075181 -6.786215789182917 2.078454117513001 1.339565757696943 0.5923451069743491 0.8478810927481397 0.1366403033949402 0.10807844774122008 0.9604687048836599 0.053823397956561714 0.0486787368898603 1.6360034335820913e-07 6.786215789182917 -0.747220650722594 SAS(ph)VSSISLTK ddPTM_PC-9_Lapatinib_30min_R1 2 SASVSSISLTK 11 0 G5E9C8;Q07889 G5E9C8 SOS1 Son of sevenless homolog 1 1 S(0.006)AS(0.989)VS(0.004)S(0.001)ISLTK;S(0.008)AS(0.987)VS(0.005)SISLTK 90.79299999999999 0.0085439 20798200.0 108785.0 90179.0 100350.0 91410.0 112195.0 128517.0 111982.0 126068.0 132331.0 110137.0 True False 107233.70595127427 89970.19606608138 92099.61036220218 98132.59633482108 105595.9106838568 123020.62749775933 117779.88002786574 131925.5795138612 117426.48927279298 129174.03370167258 0.830149085526976 0.6965037282482603 0.7129885761321522 0.7596929005210002 0.8174701033779788 0.9523634431195007 0.9117922283040132 1.0213010752497154 0.909056455912722 1.0 16.978956566026028 -6.62163877105811 1.957377798101382 0.9630984925082623 0.7412376566368308 0.821561696604352 0.04633732507717979 0.12707864261813812 0.9952265679171737 0.017215867220567876 0.01741507583941903 2.389798195928682e-07 6.62163877105811 -0.22186083587143146 SAS(ph)WGSADQLK ddPTM_PC-9_AZD4547_30min_R2 2 SASWGSADQLK 11 0 Q86VQ1;H7C0Q2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 S(0.015)AS(0.965)WGS(0.019)ADQLK;S(0.004)AS(0.97)WGS(0.026)ADQLK 110.8 0.0018913 21085900.0 42184.0 51420.0 58520.0 68888.0 59867.0 56540.0 56005.0 70102.0 57793.0 67436.0 True False 55597.63451829211 68040.50942709521 57743.986563711245 53006.935908990396 51555.50042964107 53004.54486198843 60989.33650393893 59269.34668370345 60847.8199932521 65075.08616592083 0.8543612893041089 1.04556925600703 0.8873439893184681 0.814550376066188 0.7922463644257173 0.8145136331720506 0.9372148405372137 0.9107839908591963 0.9350401755613424 1.0 15.989817696452588 -10.29780006025499 7.379001468045416 1.000000000102583 0.8875615940047791 0.18110532140394942 0.0714697870889071 2.1797872370782695e-10 0.0 0.07531967763340583 0.018267705092353193 5.037324628965247e-11 10.29780006025499 -0.11243840609780398 SAS(ph)WGSADQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SASWGSADQLK 11 0 Q86VQ1;H7C0Q2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 S(0.217)AS(0.621)WGS(0.162)ADQLK;S(0.201)AS(0.798)WGSADQLK;S(0.01)AS(0.99)WGSADQLK;S(0.043)AS(0.915)WGS(0.042)ADQLK 114.72 0.0014301 31069100.0 173782.0 221101.0 193235.0 195572.0 237539.0 174296.0 208114.0 163954.0 165814.0 147699.0 True False 203199.86024904484 243050.44607439658 197842.45524781817 184614.73489297906 190994.93813797893 165155.61092942805 188399.93530511903 159650.3812236226 168238.7160607313 174475.65951535958 1.1646315641589913 1.3930335426128604 1.1339258197811917 1.0581116896521998 1.0946795597076686 0.9465825284064275 1.079806408690111 0.9150295328705613 0.9642532174863094 1.0 17.41266625960631 -5.742667185815615 1.2785917072667627 0.9899681502658686 1.2865968311710034 0.6671671227905158 0.07595135225633323 0.2705547105980432 0.871520045938121 0.02542785869135694 0.06627695136252888 1.8085595539255015e-06 5.742667185815615 0.29662868090513483 SAS(ph)WGSADQLK ddPTM_PC-9_Lapatinib_30min_R1 2 SASWGSADQLK 11 0 Q86VQ1;H7C0Q2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 S(0.043)AS(0.957)WGSADQLK;S(0.002)AS(0.998)WGSADQLK 190.35 8.8619e-05 44976000.0 126212.0 161770.0 192406.0 168330.0 192319.0 180378.0 180021.0 162471.0 171838.0 138789.0 True False 124412.19373555374 161395.43150411916 176587.12138863793 180709.5497324187 181007.17453370188 172663.653421655 189341.60653048186 170019.99578954605 152483.7949056399 162778.49372528217 0.7643036305860009 0.991503409390818 1.0848307865943292 1.1101561735630654 1.1119845772696721 1.060727676427918 1.1631856407888237 1.044486847731158 0.9367563946314897 1.0 17.312550577938794 -4.772156919442822 2.506801555701789 1.0720306933847534 0.692095614522964 0.6906612026536387 0.06006086239736923 0.302134313726988 2.358628355596692 0.015998656712702144 0.25211269420989835 1.6898302512329243e-05 4.772156919442822 -0.37993507886178945 SAS(ph)WGSADQLKEQIAK ddPTM_PC-9_AZD4547_30min_R2 2 SASWGSADQLKEQIAK 16 1 Q86VQ1;H7C0Q2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 S(0.024)AS(0.944)WGS(0.032)ADQLKEQIAK;S(0.106)AS(0.879)WGS(0.014)ADQLKEQIAK 75.23899999999999 0.0058927 26686000.0 53949.0 50666.0 83824.0 134662.0 101731.0 82562.0 66465.0 74267.0 59682.0 78344.0 True False 71103.65979108999 67042.79367236889 82712.4389903713 103617.7564071604 87607.40665488188 77399.38508835307 72380.2562402339 62790.741635882085 62836.66867678212 75601.20040605763 0.9405096666347738 0.8867953592307909 1.0940625088770928 1.3705834808260255 1.1588097303262164 1.023785134001012 0.9573955949307168 0.8305521777250895 0.8311596686201198 1.0 16.20612152148412 -7.303880777446176 2.411400695434782 0.876776258696954 1.0927282006581973 0.3115662925839895 0.13026277014556947 0.3947647974331084 4.504655997425963 0.07176716128315677 0.0458650391606105 4.967286647253829e-08 7.303880777446176 0.21595194196124334 SAS(ph)WGSADQLKEQIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASWGSADQLKEQIAK 16 1 Q86VQ1;H7C0Q2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 S(0.053)AS(0.946)WGS(0.001)ADQLKEQIAK 80.596 0.014224 0.0 40572.0 25475.0 33409.0 54556.0 57721.0 53042.0 56415.0 60045.0 52173.0 39766.0 True False 47440.038266473246 28003.989641590266 34205.59726433807 51499.40419293841 46410.98440366548 50260.38414489557 51070.962790769976 58468.88237293635 52935.93142338123 46975.26101251719 1.009894085608853 0.5961433537139522 0.7281619415637419 1.0963090589154088 0.9879877919422023 1.0699330469181005 1.0871884836821115 1.244673922245084 1.1268895644725794 1.0 15.519613557382497 -5.764398379417644 24.978403012033873 1.0928637392354041 0.7598741056855739 0.5974823208872335 0.11606896900889833 47.16707741806474 398166.6365356677 0.03250398653895214 0.05067381866052477 1.7202898248294405e-06 5.764398379417644 -0.33298963354983024 SAS(ph)WGSTDHRK ddPTM_PC-9_Lapatinib_30min_R1 1 SASWGSTDHRK 11 1 Q9C073;D6RJ87 Q9C073 FAM117A Protein FAM117A 1 S(0.182)AS(0.801)WGS(0.008)T(0.008)DHRK 58.04 0.033818 5758800.0 12315.0 9795.3 17700.0 9075.1 14251.0 16828.0 12251.0 13167.0 16376.0 8058.5 True False 12139.385841705587 9772.619584671433 16244.774323975844 9742.513127646142 13412.784198544003 16108.305667983968 12885.296835396615 13778.786888496734 14531.562433075087 9451.400987723708 1.2844006785314965 1.0339863473536834 1.7187689259059005 1.0308009511288914 1.4191318531470287 1.7043299389060755 1.3633213586147859 1.4578565554877851 1.537503535396491 1.0 13.20631248153359 -5.2322341250195175 24.999591895072896 1.4168064966401368 1.1591935197345868 0.14735325938127963 0.233891364328109 1248.6222875147478 1068812.451804678 0.05655863618750343 0.14958635433828427 5.858222668182858e-06 5.2322341250195175 -0.25761297690554996 SASAPT(ph)LAETEKETAEHLDLAGASSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASAPTLAETEKETAEHLDLAGASSR 26 1 Q86W92-2 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.051)AS(0.166)APT(0.78)LAET(0.003)EKETAEHLDLAGASSR 68.445 0.00021666 2895400.0 5336.1 12889.0 12455.0 10242.0 12287.0 10454.0 10245.0 8244.5 8970.8 6967.4 True False 6239.396337220936 14168.5347395665 12751.974435850529 9668.173945012011 9879.450552967517 9905.773836784789 9274.51943262321 8028.090610769824 9101.980978913773 8230.534466091945 0.7580791214623941 1.72145986362585 1.5493494970935309 1.1746714608684083 1.200341313637499 1.2035395608382997 1.1268429129155904 0.9754033160111112 1.1058796991145596 1.0 13.006770402616922 -6.8208940487847505 0.9869342033023017 1.0335054613845562 1.3521363313363592 0.17306728308505614 0.23907072391029482 0.8570889525421096 1.782087140520303 0.14248846872796783 0.12235725007049944 1.5104486008104147e-07 6.8208940487847505 0.318630869951803 SASAPT(ph)LAETEKETAEHLDLAGASSRPK ddPTM_PC-9_AZD4547_30min_R2 1 SASAPTLAETEKETAEHLDLAGASSRPK 28 2 Q86W92-2 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.032)AS(0.244)APT(0.281)LAET(0.281)EKET(0.163)AEHLDLAGASSRPK 41.431000000000004 0.032202 5461100.0 5246.0 4789.7 6998.9 13428.0 12184.0 10866.0 7808.7 9529.5 10352.0 12063.0 True False 6914.118876421403 6337.876857311515 6906.090012999976 10332.382060531918 10492.461911148823 10186.547302270366 8503.65917254367 8056.934741125107 10899.185585973139 11640.678041691437 0.5939618681711047 0.5444594236359961 0.5932721434495145 0.8876099848759825 0.9013617483079385 0.8750819553454654 0.7305123586519239 0.6921362065224168 0.9363016094885005 1.0 13.506887473783282 -5.736825210407595 8.86290870045644 0.8445180466305311 0.5731361085888999 0.6853782616234059 0.08745544906770034 0.15003312219796267 47.77038574499037 0.024757526194914826 0.042089264229955355 1.8330520185464697e-06 5.736825210407595 -0.27138193804163124 SASAPT(ph)LAETEKETAEHLDLAGASSRPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASAPTLAETEKETAEHLDLAGASSRPK 28 2 Q86W92-2 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.208)AS(0.208)APT(0.576)LAET(0.008)EKET(0.001)AEHLDLAGASSRPK 52.653999999999996 0.0024642 2694500.0 6126.7 5528.2 9722.8 9272.7 13906.0 13694.0 10749.0 10383.0 9245.9 8777.6 True False 7163.829302159168 6077.003161398985 9954.628425924331 8753.180681499018 11181.21912505626 12975.862533090758 9730.776903979193 10110.457251697862 9381.103795975705 10368.90939655663 0.6908951586112013 0.5860793000483805 0.9600458491063799 0.8441756357139958 1.0783409033132632 1.2514201867170198 0.9384571252219301 0.9750743173679775 0.9047338960345278 1.0 13.339976538799712 -5.424765378038697 1.6351171810247487 1.0183943258933257 0.6179287528540445 0.6112906649259138 0.11086083358549195 0.292715512303733 1.4317874703485458 0.03489575651884675 0.12323821615241676 3.7604050042680757e-06 5.424765378038697 -0.4004655730392812 SASAPT(ph)LAETEKETAEHLDLAGASSRPK ddPTM_PC-9_Lapatinib_30min_R1 1 SASAPTLAETEKETAEHLDLAGASSRPK 28 2 Q86W92-2 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.016)AS(0.121)APT(0.671)LAET(0.178)EKET(0.012)AEHLDLAGASSRPK 48.118 0.010829 6642100.0 22118.0 12244.0 20284.0 15047.0 16042.0 15651.0 16627.0 12615.0 20164.0 11666.0 True False 21802.59326405557 12215.649770269121 18616.327818504295 16153.606575320542 15098.441099785483 14981.643214262951 17487.864703464187 13201.138953321664 17892.917983666714 13682.452556032118 1.5934711393860133 0.8927967935751158 1.360598748087528 1.1806075342975684 1.1034893808660864 1.0949530541334174 1.2781235404872202 0.9648225637370649 1.3077273910062526 1.0 13.740039233551759 -4.739790571113059 24.85033215918069 1.1416235148909102 1.5934730062676143 0.4735285231394707 0.1457928721314491 1373.3160704410273 1576320.9328870785 0.03335696243377391 1.597850459763878 1.820578580625927e-05 4.739790571113059 0.45184949137670416 SASAS(ph)PLTPCSVTR ddPTM_PC-9_AZD4547_30min_R2 1 SASASPLTPCSVTR 14 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.001)AS(0.045)AS(0.734)PLT(0.22)PCS(0.001)VTR 116.9 0.00013785 8341700.0 16937.0 17657.0 19573.0 19806.0 14613.0 16000.0 15899.0 22665.0 18082.0 20298.0 True False 22322.61368851492 23364.279948545704 19313.449231228988 15240.032699649631 12584.237188740792 14999.51747067236 17313.980199555834 19162.645039886724 19037.777604865365 19587.373198230365 1.1396430477227888 1.1928235456634158 0.9860152780962929 0.7780539302241152 0.642466810704241 0.7657748345769764 0.8839357898750853 0.9783162267831802 0.9719413324184453 1.0 14.25763631477691 -5.472024345620227 3.580074219969698 0.8478724378336133 1.1626242624823426 0.5640496000952837 0.10643604321486297 0.1796733175703277 4.611071971026516 0.032703909563421625 0.07088958293853337 3.3726840158334356e-06 5.472024345620227 0.3147518246487293 SASAS(ph)PLTPCSVTR ddPTM_PC-9_Lapatinib_30min_R1 2 SASASPLTPCSVTR 14 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.006)AS(0.288)AS(0.696)PLT(0.009)PCS(0.001)VTR;S(0.027)AS(0.001)AS(0.458)PLT(0.399)PCS(0.114)VT(0.001)R 108.66 0.00066451 27656000.0 55516.0 54004.0 55048.0 44983.0 48317.0 54377.0 44497.0 50079.0 57460.0 38958.0 True False 54724.331659612464 53878.95705599584 50522.16593142498 48291.19987888905 45475.08905487691 52051.42246897811 46800.836934506864 52405.85316237773 50988.24971937558 45691.83839172799 1.1976828594736453 1.1791812050563069 1.1057153248745506 1.0568889670158608 0.9952562789224448 1.1391842460512915 1.0242712611664064 1.146941226419667 1.1159159165853665 1.0 15.479648869486326 -5.320014677607886 2.719744118404024 1.0728097142152913 1.1946595371959265 0.4651663877783909 0.050798969363258284 0.2522896028578782 3.603481483294347 0.013879206196038813 0.03946440163883385 4.786139166022479e-06 5.320014677607886 0.12184982298063529 SASASPLTPCS(ph)VTR ddPTM_PC-9_Lapatinib_30min_R1 1 SASASPLTPCSVTR 14 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 SAS(0.011)AS(0.155)PLT(0.03)PCS(0.401)VT(0.401)R 65.157 0.039579 21355000.0 44755.0 43078.0 42525.0 40012.0 49925.0 41480.0 41636.0 38774.0 38828.0 31005.0 True False 44116.78549293819 42978.25553770442 39028.758651247044 42954.61595611916 46988.50965632652 39705.997094602724 43791.708353487375 40575.581591446215 34454.78176303369 36364.17293843437 1.2131936994037846 1.181884587626065 1.0732750258702128 1.1812345087249092 1.2921649486124562 1.0918988082535566 1.2042542099782674 1.115812029057883 0.9474925174667567 1.0 15.150230143771958 -8.118107783315162 3.726741154812779 0.9750394925251289 1.1739463941535475 0.6442718619286292 0.059382603582925395 0.15267278005611523 3.630642916159708 0.04596450795995665 0.01564701783703028 7.618899005301441e-09 8.118107783315162 0.19890690162841862 SASIT(ph)NLSLDR ddPTM_PC-9_AZD4547_30min_R2 1 SASITNLSLDR 11 0 E9PDH4;Q9Y2I7-2;Q9Y2I7-3;Q9Y2I7-4;Q9Y2I7 E9PDH4 PIKFYVE 1-phosphatidylinositol 3-phosphate 5-kinase 1 S(0.002)AS(0.433)IT(0.546)NLS(0.019)LDR 99.01299999999999 0.011585 6674900.0 18458.0 24907.0 25323.0 33528.0 32185.0 23859.0 31813.0 30676.0 25673.0 23763.0 True False 24327.260049749562 32957.700667068486 24987.200474245725 25798.637602436287 27716.668303539474 22367.092958298243 34644.29537005282 25935.729064353203 27030.02236753171 22931.064602894272 1.0608866387598537 1.4372512239535835 1.089665957815667 1.1250518913622563 1.2086952256041867 0.9754057801343926 1.5108018737900268 1.1310303081645714 1.178751306824197 1.0 14.485015714915717 SASLS(ph)SLLITPFPSPNSSLTR ddPTM_PC-9_Lapatinib_30min_R1 1 SASLSSLLITPFPSPNSSLTR 21 0 J3KNG8;Q8TF40;Q8TF40-2;Q8TF40-3;A0A087WX11 J3KNG8 FNIP1 Folliculin-interacting protein 1 1 SAS(0.019)LS(0.973)S(0.008)LLITPFPSPNSSLTR 188.9 2.7655e-15 14206000.0 35365.0 22102.0 28826.0 27764.0 28674.0 25269.0 23640.0 17612.0 22537.0 18137.0 True False 34860.68861485329 22050.824176942842 26456.03755157783 29805.857177988917 26987.45169525303 24188.303774916018 24863.963528591645 18430.317815767034 19998.6457348689 21271.956283966614 1.6388097149827707 1.0366147749919592 1.2437049605784791 1.4011808213640693 1.2686868727534184 1.1370982269810113 1.1688611614594397 0.8664138629157762 0.940141351735597 1.0 14.376665096975692 -7.342829451867191 1.3116564400230883 0.9262976222726262 1.3026051963733971 0.5221982102709577 0.15162635304068095 0.3700929160779956 1.2281654961592605 0.09791383293936927 0.05286762972548245 4.541199152508124e-08 7.342829451867191 0.37630757410077087 SASLS(ph)YPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASLSYPDR 9 0 Q6P4Q7-2;Q6P4Q7 Q6P4Q7-2 CNNM4 Metal transporter CNNM4 1 S(0.066)AS(0.443)LS(0.491)YPDR 123.96 0.0014742000000000002 10344000.0 38816.0 37366.0 39032.0 24384.0 55683.0 18257.0 23941.0 19588.0 14779.0 15699.0 True False 45386.78214905414 41075.44953670899 39962.6709096843 23017.84353399462 44772.315873760075 17299.57078038835 21673.135162170056 19073.835755201555 14995.114915878932 18545.10442678439 2.4473726922509402 2.2148944859746593 2.1548905840598485 1.2411816619781513 2.414239081290702 0.9328376040526827 1.168671508307492 1.0285105608601226 0.8085753830656103 1.0 14.17875077117467 -6.2838157569322 0.5236755327161778 0.8329398716398952 2.5425728704824015 0.6834636178444418 0.3604784628411058 0.6879974623464498 0.37560609338236517 0.2828589676582017 0.5954471708104636 5.202166440125538e-07 6.2838157569322 1.7096329988425063 SASLS(ph)YPDR ddPTM_PC-9_Lapatinib_30min_R1 1 SASLSYPDR 9 0 Q6P4Q7-2;Q6P4Q7 Q6P4Q7-2 CNNM4 Metal transporter CNNM4 1 S(0.002)AS(0.374)LS(0.623)YPDR 105.17 0.0026544 14891000.0 54325.0 144420.0 56539.0 21026.0 41718.0 21925.0 26605.0 27127.0 61830.0 17611.0 True False 53550.31553801513 144085.60436313858 51890.58166685146 22572.322180679846 39264.22926074372 20987.318859671283 27982.47672073523 28387.4194519823 54866.05430123553 20655.037884817557 2.592603113905551 6.975809251313376 2.5122481961165284 1.0928240512825003 1.9009516941919922 1.0160871636598627 1.3547531055996607 1.3743581401440281 2.656303736027747 1.0 14.334206085891548 -5.476963930469706 7.636993408490498 1.5143582259481791 4.791628426596554 0.5902868735457515 1.086239520416739 0.16452860364833485 24.15717562562049 0.2612856314587911 0.5384076565381856 3.334541060313554e-06 5.476963930469706 3.277270200648375 SASNKS(ph)PLVLEANR ddPTM_PC-9_Lapatinib_30min_R1 1 SASNKSPLVLEANR 14 1 Q92560;F8W6N3 Q92560 BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1;Ubiquitin carboxyl-terminal hydrolase 1 SAS(0.002)NKS(0.998)PLVLEANR 120.59 0.00040799 6540700.0 7156.3 11929.0 11320.0 10023.0 11960.0 12101.0 11150.0 11405.0 10304.0 7243.7 True False 7054.249849695311 11901.379133415581 10389.313296463644 10760.124855747834 11256.536314264697 11583.468438808766 11727.292442631002 11934.917935999487 9143.455014069721 8495.763893376457 0.8303255526198189 1.4008603914586468 1.2228815945042273 1.266528235811348 1.3249587036005812 1.3634404844795147 1.3803693923007838 1.4048081003409585 1.0762369492398702 1.0 13.052527957279189 -4.752901710811552 24.999684512154698 1.2901011918875172 0.8303246896939983 0.49493816026639503 0.13233977601227204 251.07115101732114 735121.7102666245 0.030882648683556814 0.35072305052944946 1.7664375542204327e-05 4.752901710811552 -0.45977650219351884 SASPDY(ph)NRT(ph)NS(ph)PS(ph)S(ph)AKKPK ddPTM_PC-9_Lapatinib_30min_R1 1 SASPDYNRTNSPSSAKKPK 19 3 Q14669;Q14669-2;Q14669-3;G5E9G6;F8W9P3;C9JLJ5;C9JSX9;C9JLD7 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 5 S(0.046)AS(0.123)PDY(0.92)NRT(0.927)NS(0.989)PS(0.997)S(0.999)AKKPK 44.998000000000005 0.041795 0.0 4583.2 4668.2 3802.8 2589.4 3272.4 3017.7 2562.9 4104.5 4584.4 1308.1 True False 4517.842727544058 4657.391069713352 3490.148463232505 2779.83311398518 3079.923865785936 2888.640005602282 2695.59442163399 4295.210054213932 4068.0565961278353 1534.203342066313 2.9447483287706087 3.0357065077440337 2.2748930128987097 1.811906569204323 2.0075069460074295 1.882827345240802 1.7569994457211122 2.799635443649216 2.6515758925729163 1.0 10.583273993806015 -5.350916838124503 3.7616214083774406 2.0489196746012186 2.998230048206328 0.4093669799098739 0.47024259616625375 0.23458698681847986 6.114259361656493 0.12743947677822673 0.2981078845895465 4.457415940779767e-06 5.350916838124503 0.9493103736051096 SASPS(ph)TQQEK ddPTM_PC-9_AZD4547_30min_R2 1 SASPSTQQEK 10 0 P55198;Q6P2C6 P55198 MLLT6 Protein AF-17 1 S(0.029)AS(0.339)PS(0.468)T(0.163)QQEK 96.82 0.0053835 2123900.0 15079.0 10964.0 9197.2 8704.0 6703.3 11160.0 9181.6 8927.2 13567.0 12617.0 True False 19873.80833731572 14507.89858729428 9075.23911865628 6697.427275459476 5772.662502380492 10462.163435793977 9998.74461288395 7547.706366647992 14284.123922420551 12175.282670315915 1.632307756251876 1.191586181622331 0.745382211189418 0.5500839246868752 0.4741296492815396 0.8592953214385216 0.8212330574682674 0.6199204216465349 1.173206759071485 1.0 13.571667646914888 -4.97490702073026 2.3992109090714333 0.7513790165440873 1.6754228641792628 0.6466740454928284 0.19888464367311273 0.22564388066928984 2.14625937067555 0.053627932355740524 0.3679256170139838 1.0594805279241375e-05 4.97490702073026 0.9240438476351754 SASPT(ph)VPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SASPTVPR 8 0 Q92817;K7EKI0;K7EQ87 Q92817 EVPL Envoplakin 1 S(0.04)AS(0.273)PT(0.687)VPR;S(0.035)AS(0.252)PT(0.714)VPR;S(0.035)AS(0.26)PT(0.705)VPR 88.177 0.027313999999999998 118549000.0 355779.0 392112.0 529427.0 588617.0 529668.0 521549.0 512395.0 521600.0 450363.0 473326.0 True False 416005.35774444323 431038.2879820702 542050.5475430776 555638.6978120618 425883.3576535515 494198.05230545875 463857.236181452 507908.5526808834 456948.7068719118 559136.2569534453 0.7440142766114354 0.7709002637937665 0.9694426730552903 0.9937447105282698 0.7616808109959704 0.883859785802813 0.8295960607327841 0.9083806431160711 0.8172403438147247 1.0 19.092840373385314 SASPYPSHS(ph)LS(ph)SPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASPYPSHSLSSPQR 15 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 2 SASPYPS(0.317)HS(0.765)LS(0.918)S(0.001)PQR 102.97 0.016673 3190900.0 5409.7 4799.3 47873.0 5663.2 8831.8 5846.9 5095.0 5917.4 4283.1 4011.0 True False 6325.455363554679 5275.742786531272 49014.47387936354 5345.909264342124 7101.272189606781 5540.278271120808 4612.364715394361 5762.074520003558 4345.732234670886 4738.162548941472 1.3350017645485412 1.1134575338091552 10.344616372503642 1.1282663287979484 1.498739673081338 1.1692883504721747 0.9734500806488341 1.216098954074683 0.9171766881745632 1.0 12.210111977653307 -5.912569216801582 24.998627974461304 1.1469687459588063 4.247133427665965 0.27031376795473006 2.3603976608506287 30.07262896584802 8592.674225118264 0.6710427566136252 0.9953172970543104 1.2230121827995988e-06 5.912569216801582 3.1001646817071586 SASQS(ph)SLDKLDQELK ddPTM_PC-9_AZD4547_30min_R2 2 SASQSSLDKLDQELK 15 1 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 SAS(0.007)QS(0.789)S(0.203)LDKLDQELK;SAS(0.017)QS(0.733)S(0.25)LDKLDQELK 223.76 1.5891e-23 24087000.0 78400.0 85378.0 66916.0 53718.0 60845.0 72161.0 77861.0 70963.0 66137.0 65710.0 True False 103329.56917869573 112974.76884221182 66028.65011786229 41334.14503482676 52397.72201114986 67648.76126257438 84790.47816325654 59997.29891751516 69632.86679863854 63409.512900567315 1.6295594217972815 1.7816690851949606 1.0413051149186723 0.6518603147077155 0.8263385037086615 1.0668550847986271 1.3371886060095872 0.9461876644849352 1.0981454298163447 1.0 15.95241167393536 -5.282973039450067 7.73499929797483 0.9895884165682493 1.7063201860829018 0.7317483579713182 0.17184959256336058 0.0982817827267434 29.637627707021657 0.04958282928739842 0.10820569152462733 5.2122706733520835e-06 5.282973039450067 0.7167317695146526 SASQS(ph)SLDKLDQELK ddPTM_PC-9_Lapatinib_30min_R1 2 SASQSSLDKLDQELK 15 1 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 S(0.007)AS(0.042)QS(0.475)S(0.475)LDKLDQELK;S(0.003)AS(0.013)QS(0.492)S(0.492)LDKLDQELK 63.29 0.018765999999999998 75835000.0 95928.0 154183.0 124350.0 134614.0 131151.0 110581.0 115395.0 102040.0 96756.0 85103.0 True False 94560.04912895933 153825.998736475 114126.42300488119 144513.96261914002 123436.9560327869 105851.70840690122 121369.58846792871 106781.15091533416 85858.32039415078 99812.9401573806 0.9473726450684777 1.5411428467484178 1.1434030780471123 1.4478479683223122 1.2366828974094641 1.0605008552999136 1.2159704771401239 1.069812699104609 0.8601922782634517 1.0 16.60693924411685 -7.589512165761879 0.9464127619295273 0.937149588762528 1.2753216210089535 0.33429419761603574 0.1663231108892673 0.6150698459009603 1.0097943301068304 0.13435275682548636 0.06123678093892157 2.573284678759726e-08 7.589512165761879 0.33817203224642556 SASQS(ph)SLDKLDQELKEQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASQSSLDKLDQELKEQQK 19 2 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 S(0.001)AS(0.01)QS(0.495)S(0.495)LDKLDQELKEQQK 88.0 0.0032116999999999996 10923000.0 14027.0 7818.5 9548.5 12218.0 14461.0 10201.0 10501.0 10578.0 8226.0 7569.2 True False 16401.494054121566 8594.669009333596 9776.172452887899 11533.465071290455 11627.470859157089 9666.041602165826 9506.269259343715 10300.33870831744 8346.289687936942 8941.436042245772 1.8343243721287181 0.961217970885907 1.0933559672851465 1.2898895677157534 1.3004030677198335 1.0810390586586422 1.0631703022231849 1.1519781229381092 0.9334395111146654 1.0 13.126290839185764 -4.754041783610189 24.999969220097636 1.1126036415363143 1.834325641964089 0.776986366225678 0.11821880850458895 129.23106603030715 436696.28850347013 0.030803117584963846 0.311696862040877 1.7618065342905165e-05 4.754041783610189 0.7217220004277747 SASQS(ph)SLDKLDQELKEQQK ddPTM_PC-9_Lapatinib_30min_R1 2 SASQSSLDKLDQELKEQQK 19 2 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 S(0.025)AS(0.114)QS(0.43)S(0.43)LDKLDQELKEQQK;SAS(0.006)QS(0.497)S(0.497)LDKLDQELKEQQK 100.85 0.0011975 75004000.0 640446.0 371332.0 365571.0 436152.0 366475.0 295947.0 190737.0 215766.0 263643.0 211931.0 True False 631313.1225965872 370472.2035685708 335515.1635248691 468228.0730404197 344919.6610175718 283290.03669615247 200612.42857669122 225791.2760525088 233948.7490561321 248562.9909696933 2.539851649409713 1.4904560092525665 1.349819465142249 1.8837400982896513 1.3876549347590812 1.1397112482070726 0.8070888904018355 0.9083865428704911 0.9412050770046332 1.0 17.923251981128217 -1.5228787452810875 0.29507796342572834 0.848103839138537 12.867569285941366 0.7436571326732668 0.25542526773786384 29.510414010252642 0.4197909626209209 0.2860719427536227 186.1700364621713 0.0299999999999482 1.5228787452810875 12.01946544680283 up SASQSS(ph)LDKLDQELK ddPTM_PC-9_AZD4547_30min_R2 1 SASQSSLDKLDQELK 15 1 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 S(0.017)AS(0.056)QS(0.263)S(0.663)LDKLDQELK 50.938 0.044959 29497000.0 60943.0 50866.0 56709.0 50829.0 59419.0 62051.0 53004.0 62868.0 49995.0 68733.0 True False 80321.60630685282 67307.43976115569 55957.00160699761 39111.159350221715 51169.69749659815 58170.94116079314 57721.25331764627 53153.19516292075 52637.633633184574 66326.67859069693 1.2109999778900256 1.0147868277335437 0.8436575265936235 0.5896746253732581 0.7714798718079527 0.8770368484718949 0.8702569545784904 0.8013848468265692 0.7936117826434866 1.0 16.017301662085288 -5.013410582398673 2.347563169253181 0.8047464751762551 1.2214310837302826 0.6187400412731562 0.09824994119234227 0.24178517418606899 2.2425463713357647 0.027235789379746272 0.1690962610347692 9.695928798146332e-06 5.013410582398673 0.41668460855402756 SASQSS(ph)LDKLDQELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SASQSSLDKLDQELK 15 1 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 SASQS(0.407)S(0.593)LDKLDQELK;SASQS(0.003)S(0.997)LDKLDQELK 239.19 1.5725999999999998e-31 7013700.0 45288.0 62934.0 33092.0 39610.0 39027.0 20330.2 29139.0 21112.0 19019.4 19571.2 True False 52954.36392122748 69181.67160368353 33881.03878210887 37390.78011735267 31379.939507663636 19264.048522728335 26378.742971909003 20557.83237001304 19297.52274383027 23119.303634466058 2.2904826528721034 2.992376963315975 1.465486993803711 1.6172969873370588 1.3573047010327202 0.8332451888390643 1.1409834564646575 0.8892063833343838 0.834693079382447 1.0 14.496810323312241 -5.5767643294993166 0.9220373875353001 0.9466922647275122 2.8317919527208577 0.8123206594715018 0.2903866839340046 0.322241019337997 0.4531555013647513 0.11057766266963999 0.4800216570808056 2.6499377408895882e-06 5.5767643294993166 1.8850996879933455 up SASQSS(ph)LDKLDQELK ddPTM_PC-9_Lapatinib_30min_R1 2 SASQSSLDKLDQELK 15 1 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 SASQS(0.383)S(0.617)LDKLDQELK;S(0.003)AS(0.014)QS(0.31)S(0.673)LDKLDQELK 159.14 0.0012559000000000001 36270800.0 116760.0 183459.0 147578.0 168018.0 173666.0 134156.0 127360.0 140254.0 102915.0 102048.0 True False 115094.98098883824 183034.2119571873 135444.70650755384 180374.60421161746 163451.30732049278 128418.4606129105 133954.07762273398 146770.71286240025 91323.62895700542 119686.86082958715 0.9616342194212368 1.52927573409913 1.1316589437532585 1.507054349670336 1.3656579025263136 1.0729537037131887 1.1192045366906298 1.226289267218527 0.7630213402207454 1.0 16.868905256990253 -7.645675841258517 0.9749321639179372 0.9280900090772058 1.3003206785923853 0.33197590963580925 0.18913621197346114 0.6294124825587581 1.0902180599785343 0.15609344809497824 0.06821343659196705 2.26112284959457e-08 7.645675841258517 0.37223066951517947 SASQSS(ph)LDKLDQELKEQQK ddPTM_PC-9_AZD4547_30min_R2 2 SASQSSLDKLDQELKEQQK 19 2 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 SAS(0.001)QS(0.058)S(0.941)LDKLDQELKEQQK;SAS(0.002)QS(0.222)S(0.775)LDKLDQELKEQQK 119.96 0.00013225 26342000.0 88812.0 67879.0 63043.0 92180.0 92055.0 88296.0 79813.0 68565.0 61569.0 90929.0 True False 117052.36859564201 89819.55930380782 62207.00862843558 70929.32516680317 79274.7522349644 82774.83716190523 86916.20238173152 57969.854716957176 64823.411644395295 87745.6033866334 1.3339969648379328 1.023636009522163 0.7089473002348946 0.8083518994594786 0.9034612467778711 0.9433502530853257 0.9905476630977476 0.6606582265042344 0.738765352820744 1.0 16.421039218571096 -4.876825355321171 3.1264206317286596 0.8420394626006121 1.360763726096985 0.6411669683248037 0.11217372091008568 0.19161332295579522 3.1232524143847953 0.030202013613378962 0.2184086589885333 1.327928355825427e-05 4.876825355321171 0.5187242634963728 SASQSS(ph)LDKLDQELKEQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASQSSLDKLDQELKEQQK 19 2 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 S(0.001)AS(0.015)QS(0.405)S(0.579)LDKLDQELKEQQK 137.12 0.00031495 8837200.0 16454.0 9807.9 7351.2 17416.0 18501.0 10872.0 8969.8 11151.0 12853.0 9304.8 True False 19239.33721868654 10781.563493847027 7526.480487581252 16440.237983433828 14875.861860539757 10301.853180937833 8120.115608271712 10858.29806546113 13040.950809512953 10991.686583243723 1.750353512446029 0.9808834533440011 0.6847430037765992 1.4956974854519731 1.3533739110808767 0.9372404410295407 0.7387506500276693 0.9878645995978508 1.1864376509236745 1.0 13.424125152423771 -6.777839479810661 24.857222026923825 0.954843369182457 1.2198043316992488 0.19042339202630987 0.2868075190738601 445.1015300643141 674624.8564744068 0.10540014401843045 0.09322306473892353 1.6678635600167725e-07 6.777839479810661 0.2649609625167918 SASQSS(ph)LDKLDQELKEQQK ddPTM_PC-9_Lapatinib_30min_R1 1 SASQSSLDKLDQELKEQQK 19 2 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 S(0.001)AS(0.004)QS(0.171)S(0.824)LDKLDQELKEQQK 108.99 0.00048666 24693000.0 59033.0 38831.0 34105.0 38505.0 31232.0 28468.0 23689.0 20595.0 26794.0 23187.0 True False 58191.178594673635 38741.08920526951 31301.01854910715 41336.78614891456 29394.995164474523 27250.490002149236 24915.500508832796 21551.91888574393 23776.177566671573 27194.842055264562 2.1397873345401024 1.424574892788162 1.1509910035696524 1.5200230273414037 1.0809033236795005 1.0020462684347122 0.916184784533782 0.792500241109941 0.874289967132529 1.0 14.73104542635844 -1.5228787452803758 0.4113301612949816 0.8830195078785292 21.214708481602106 0.8368224916470508 0.15558934156453386 30.443042873597477 0.39624784435443017 0.11447129960898844 506.01964114749507 0.02999999999999736 1.5228787452803758 20.331688973723576 up SASS(ph)DTSEELNSQDSPPK ddPTM_PC-9_AZD4547_30min_R2 1 SASSDTSEELNSQDSPPK 18 0 J3QRP6;O14745;O14745-2 J3QRP6 SLC9A3R1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 1 SAS(0.227)S(0.621)DT(0.041)S(0.11)EELNSQDSPPK 238.88 1.4669e-43 20492000.0 31268.0 41972.0 38079.0 36205.0 32065.0 37277.0 35873.0 47271.0 40857.0 32860.0 True False 41210.573585197155 55538.62819280514 37574.04757962339 27858.49661167398 27613.32823218871 34946.06329714083 39065.62750479065 39966.35312951621 43016.61760878133 31709.581401805586 1.2996252792807466 1.751477810099464 1.184943033574195 0.8785513835287552 0.870819702167887 1.1020663708651466 1.231981810474679 1.2603872824142823 1.3565810618468745 1.0 14.952631212099202 -5.42001671282192 6.499565688265034 1.1015027613907993 1.5209028546304795 0.46525845887610373 0.17976848556601518 0.21337003222352752 11.477952672083186 0.0506312408787745 0.10637530171398404 3.801747658896377e-06 5.42001671282192 0.4194000932396802 SASS(ph)DTSEELNSQDSPPK ddPTM_PC-9_Lapatinib_30min_R1 1 SASSDTSEELNSQDSPPK 18 0 J3QRP6;O14745;O14745-2 J3QRP6 SLC9A3R1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 1 S(0.001)AS(0.232)S(0.756)DT(0.011)SEELNSQDSPPK 305.63 7.636299999999998e-138 22947000.0 21182.0 50216.0 48151.0 36962.0 51448.0 56192.0 57089.0 65353.0 43116.0 53958.0 True False 20879.94079569694 50099.72793726184 44192.21064823506 39680.30878161742 48421.929790659735 53788.79914994978 60044.78908137769 68389.53896285628 38259.82204839189 63284.568405484366 0.32993731839826285 0.7916578906923556 0.6983094261634448 0.6270139748346399 0.7651459275254122 0.8499512678242163 0.9488061717771641 1.0806669095799586 0.6045679541219123 1.0 15.949566128823514 -4.363308427448486 0.3677546856002959 0.9350045157813236 7.725257825246126e-12 0.48786674997087454 0.14923626332937226 7.829487214702659 0.6665934742909316 0.13167976393595235 3.4434486888831413 4.3320311673502496e-05 4.363308427448486 -0.9350045157735983 SASS(ph)GAEGDVSSER ddPTM_PC-9_AZD4547_30min_R2 1 SASSGAEGDVSSER 14 0 Q8TEA8 Q8TEA8 DTD1 D-tyrosyl-tRNA(Tyr) deacylase 1 1 SAS(0.35)S(0.65)GAEGDVSSER 118.52 0.00011447 8587500.0 8809.1 14262.0 15588.0 14219.0 11385.0 11997.0 12958.0 16080.0 13645.0 13244.0 True False 11610.210559337349 18871.912591389195 15381.292934981728 10941.029231360104 9804.389269404901 11246.825693478515 14111.236897027782 13595.205481640354 14366.246843180395 12780.331591159867 0.9084436093479852 1.4766371636587945 1.2035128216564381 0.8560833616342157 0.7671467050343654 0.8800104765089134 1.1041369933459708 1.0637599959490984 1.1240903055377298 1.0 13.641637647658765 -4.480070822859279 18.48828231378781 1.0495841959225956 0.035413364551699245 0.04887749759939508 0.19058429341242036 43073621.454813704 449617995.4624812 0.052671479707526676 1562202621.160808 3.3107712645915925e-05 4.480070822859279 -1.0141708313708964 SASS(ph)GAEGDVSSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SASSGAEGDVSSER 14 0 Q8TEA8 Q8TEA8 DTD1 D-tyrosyl-tRNA(Tyr) deacylase 1 1 SAS(0.037)S(0.963)GAEGDVSSER;SAS(0.31)S(0.69)GAEGDVSSER 138.55 8.8707e-05 17535500.0 25517.0 47686.0 40231.0 35557.0 35593.0 31927.0 34188.0 24686.0 23610.0 23593.0 True False 29836.524116277193 52419.95093420504 41190.25961691716 33564.85656734938 28618.807156488383 30252.691915728697 30949.465140314514 24038.018656979057 23955.25158426831 27870.224137914756 1.0705519973083917 1.8808586064757455 1.4779306909441672 1.2043267539311828 1.0268595980738904 1.0854843422149887 1.1104849744717606 0.8624982180992813 0.8595284869517607 1.0 14.76643698447979 -5.950231997791888 2.3743487101477254 0.9933553536395945 1.522061987682246 0.5447007297710583 0.19796525657147912 0.21005515630767166 2.3955324901749626 0.0602263740704746 0.09594539945974166 1.121419238101682e-06 5.950231997791888 0.5287066340426516 SASS(ph)GAEGDVSSEREP ddPTM_PC-9_AZD4547_30min_R2 1 SASSGAEGDVSSEREP 16 1 Q8TEA8 Q8TEA8 DTD1 D-tyrosyl-tRNA(Tyr) deacylase 1 1 SAS(0.288)S(0.712)GAEGDVSSEREP 137.17 5.9384e-05 145430000.0 13173.0 16173.0 25196.0 27747.0 20787.0 20283.0 16637.0 23117.0 14774.0 18943.0 True False 17361.739984578562 21400.605969747394 24861.88457722606 21350.357836876636 17901.083859738243 19014.700803602973 18117.6607698604 19544.798825813417 15554.923478281211 18279.811335800452 0.9497767600355986 1.1707235691122786 1.360073368401501 1.1679747369745885 0.979281652906314 1.040202245761873 0.9911295273807074 1.0692013427696339 0.8509345743529294 1.0 14.157963560103546 -6.254473640550604 16.702647645389856 0.9946387852770155 1.176890462985954 0.38514279279820995 0.10668530191082638 6.4019200401917695 15346.269714335356 0.03276229079416374 0.040893687097679064 5.565784146905387e-07 6.254473640550604 0.18225167770893846 SASS(ph)GAEGDVSSEREP ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASSGAEGDVSSEREP 16 1 Q8TEA8 Q8TEA8 DTD1 D-tyrosyl-tRNA(Tyr) deacylase 1 1 SAS(0.004)S(0.996)GAEGDVSSEREP 90.853 0.031686 0.0 9355.0 10226.0 11531.0 13452.0 13481.0 11684.0 16580.0 13168.0 12255.0 8994.0 True False 10938.616730327738 11241.169698720392 11805.942771561024 12698.328051972436 10839.494824168234 11071.270471493539 15009.422371194994 12822.35395264928 12434.206190817804 10624.541003535172 1.0295613454442936 1.0580381491285171 1.1111955582488462 1.1951883895734638 1.0202318218322597 1.042046942810021 1.4127125460008871 1.206861919812142 1.170328787538256 1.0 13.375112895507813 SASS(ph)GAEGDVSSEREP ddPTM_PC-9_Lapatinib_30min_R1 1 SASSGAEGDVSSEREP 16 1 Q8TEA8 Q8TEA8 DTD1 D-tyrosyl-tRNA(Tyr) deacylase 1 1 SAS(0.261)S(0.739)GAEGDVSSEREP 150.37 0.00014891 114130000.0 14264.0 14521.0 16387.0 13561.0 14847.0 13412.0 13256.0 11847.0 16366.0 12199.0 True False 14060.592744302758 14487.377516667582 15039.724115649267 14558.321178169856 13973.728650325087 12838.400024899027 13942.330817893859 12397.454869599824 14522.688738379762 14307.580895854257 0.9827372528347496 1.0125665283406102 1.0511716987745396 1.0175249949059 0.9766660592060041 0.8973145158745224 0.9744715699586761 0.8664955284783392 1.0150345361729065 1.0 13.804492143537 -6.44661927746694 3.956480535628803 0.943136768289541 1.0176766785472895 0.31383151442623425 0.04455217078297405 0.23987066167074406 7.105723174840636 0.013690212738959609 0.015285457993024922 3.5758617729052125e-07 6.44661927746694 0.07453991025774853 SASS(ph)SAAGSPGGLTSLQQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASSSAAGSPGGLTSLQQQK 20 0 E5RJ10;E5RHB8;E5RJX6;E5RG91;Q8NEZ2-3;Q8NEZ2-2;Q8NEZ2 E5RJ10 VPS37A Vacuolar protein sorting-associated protein 37A 1 SAS(0.017)S(0.631)S(0.352)AAGS(0.001)PGGLTSLQQQK 276.3 4.3969999999999985e-202 0.0 13322.0 12170.0 12945.0 13323.0 17430.0 14792.0 13421.0 9103.5 11784.0 8033.9 True False 15577.151478506283 13378.157171271967 13253.657894185882 12576.555503748787 14014.716622301921 14016.28148017223 12149.66572037443 8864.542770955555 11956.318706862246 9490.382473682586 1.6413618230564133 1.4096541639254707 1.396535696104882 1.3251895314677093 1.4767283258778654 1.4768932146876315 1.2802082270199542 0.9340553761176092 1.2598352848283885 1.0 13.212250515403312 -7.533367919769564 4.4618790520230425 1.0734337282490025 1.4419131462159338 0.7171632417900321 0.10937120307348099 0.10749886305097697 5.389028245874102 0.05094330907684621 0.029945565496512373 2.9284113418939527e-08 7.533367919769564 0.3684794179669313 SASS(ph)SWLEGTSTQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASSSWLEGTSTQAK 15 0 Q9BZL4-3;K7EL81;Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-3;Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 SAS(0.037)S(0.482)S(0.482)WLEGTSTQAK 261.61 8.252799999999999e-51 13319000.0 23737.0 26850.0 40480.0 38281.0 45399.0 36139.0 37867.0 29120.0 32709.0 32036.0 True False 27755.205272879717 29515.490554531832 41445.196721254884 36136.23967867654 36503.391849448366 34243.80722092645 34279.96362666113 28355.630855190375 33187.30724565153 37843.873203163515 0.7334134411632991 0.7799278471333774 1.095162656812578 0.9548768828359717 0.9645786427166474 0.9048705727632519 0.9058259825211424 0.749279300851796 0.876953240686719 1.0 15.207772131150568 -10.24283511311499 18.093500393099188 0.9999999995404248 0.8896819695023558 0.0970538315669266 0.1043620018463115 0.0 0.0 0.10827100462457948 0.026259575779934086 5.716956489211178e-11 10.24283511311499 -0.11031803003806906 SASSASS(ph)LFSPSSTLFSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASSASSLFSPSSTLFSSSR 20 0 Q5T1Z4;Q5T1Z8;Q14671-2;Q14671;Q14671-3;E9PR38;H0YEH2;Q14671-4;H0YDK8 Q5T1Z4 PUM1 Pumilio homolog 1 1 SASSAS(0.002)S(0.589)LFS(0.409)PSSTLFSSSR 251.0 5.3145e-55 14308000.0 15972.0 12962.0 18045.0 16011.0 21415.0 15874.0 16829.0 16998.0 15458.0 12378.0 True False 18675.744138620485 14248.781697126318 18475.261236043596 15113.955578362364 17218.884478863773 15041.539495420087 15234.83528859112 16551.820510869708 15684.04400633712 14622.033415805909 1.2772330364416111 0.9744733370479021 1.2635220225986135 1.0336425275861225 1.1775984905253163 1.0286899959591602 1.0419094838152123 1.1319780252299085 1.0726308414384564 1.0 13.835856333446438 -1.5228787452942176 0.10647654148929596 0.9714910256155498 1.5544172461306132 0.20704569447192278 0.09105729474322094 206.0063432304099 1.5454634564986989 0.8839635543104529 17.595473657758017 0.0299999999990412 1.5228787452942176 0.5829262205150634 SASSASSLFS(ph)PSSTLFSSSR ddPTM_PC-9_AZD4547_30min_R2 2 SASSASSLFSPSSTLFSSSR 20 0 Q5T1Z4;Q5T1Z8;Q14671-2;Q14671;Q14671-3;E9PR38;H0YEH2;Q14671-4;H0YDK8 Q5T1Z4 PUM1 Pumilio homolog 1 1 SASSAS(0.008)S(0.293)LFS(0.694)PS(0.003)S(0.001)TLFSSSR;SASSAS(0.002)S(0.018)LFS(0.918)PS(0.033)S(0.01)T(0.017)LFSS(0.001)SR 235.37 3.2691e-44 49314000.0 34261.0 31914.0 44639.0 74899.0 61389.0 49935.0 40790.0 64483.0 47685.0 48823.0 True False 45155.28532692978 42229.57638771525 44047.05769339553 57632.19272801468 52866.19700127338 46812.55655612655 44420.23097929951 54518.634021928774 50205.53174914306 47113.721630564636 0.9584317214634062 0.8963328500951867 0.9349093251173002 1.2232570625587402 1.1220976643665712 0.9936076993280295 0.9428300172848636 1.1571710349997115 1.0656244085920956 1.0 15.523859678141818 -5.567647914603389 24.994692022349437 1.0726015505435968 0.9244416727954722 0.40408008560460273 0.07914841794737836 125.23561125704248 69918.62696329581 0.022614469514337272 0.03916943091622448 2.7061513697840405e-06 5.567647914603389 -0.14815987774812467 SASSASSLFS(ph)PSSTLFSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASSASSLFSPSSTLFSSSR 20 0 Q5T1Z4;Q5T1Z8;Q14671-2;Q14671;Q14671-3;E9PR38;H0YEH2;Q14671-4;H0YDK8 Q5T1Z4 PUM1 Pumilio homolog 1 1 SASSAS(0.004)S(0.087)LFS(0.884)PS(0.019)S(0.006)TLFSSSR 147.6 0.00016232 14324000.0 15291.0 20231.0 20517.0 18834.0 27166.0 22057.0 24827.0 21895.0 20484.0 15132.0 True False 17879.464288983585 22239.399977978905 21006.203091155807 17778.792040651857 21843.017312762706 20900.29209087066 22475.206828085556 21320.2794496701 20783.53974807929 17875.311815153902 1.0002323021759074 1.2441405334885023 1.175151701317326 0.9946003865275111 1.2219656663133092 1.1692267137489771 1.2573322949830763 1.1927221001871253 1.162695228088828 1.0 14.125680787888173 SASSASSLFS(ph)PSSTLFSSSR ddPTM_PC-9_Lapatinib_30min_R1 2 SASSASSLFSPSSTLFSSSR 20 0 Q5T1Z4;Q5T1Z8;Q14671-2;Q14671;Q14671-3;E9PR38;H0YEH2;Q14671-4;H0YDK8 Q5T1Z4 PUM1 Pumilio homolog 1 1 SASSASS(0.003)LFS(0.995)PS(0.001)STLFSSSR;SASSASSLFS(0.528)PS(0.441)S(0.024)T(0.007)LFSSSR 199.91 8.091599999999999e-16 37072000.0 63394.0 47431.0 66359.0 50318.0 55800.0 56889.0 52079.0 44372.0 63354.0 41063.0 True False 62489.98993496419 47321.17643365196 60903.21917314761 54018.553575927326 52517.95370702094 54455.990084736164 54775.39579549597 46433.685107949976 56218.40537280406 48160.68483699182 1.2975311739538669 0.9825685949819584 1.264583744589287 1.1216317574960255 1.0904735654149655 1.1307146123243865 1.1373466963954681 0.9641408809927189 1.167309093778151 1.0 15.55556828667836 -1.522878745789274 0.07078088775041165 0.8764689340988951 1.6713716851876639 0.22715813324345735 0.09359103296996359 383.216652866958 2.008817372182901 3.899742222400743 30.305539558150475 0.029999999964843913 1.522878745789274 0.7949027510887687 SASSDT(ph)SEELNSQDSPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SASSDTSEELNSQDSPPK 18 0 J3QRP6;O14745;O14745-2 J3QRP6 SLC9A3R1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 1 SAS(0.009)S(0.076)DT(0.866)S(0.049)EELNSQDSPPK;SAS(0.008)S(0.337)DT(0.652)S(0.002)EELNSQDSPPK 324.79 2.259399999999999e-176 30356000.0 102430.0 173243.0 121830.0 128536.0 134812.0 87254.0 118981.0 78282.0 81926.0 82246.0 True False 119769.3759152829 190441.4201168994 124734.88924284767 121334.54463933468 108396.55635603961 82678.24663811176 107710.25833215652 76227.1804466352 83124.01276123524 97156.5487410223 1.2327462993208693 1.960150114271088 1.2838546743291324 1.2488560597470435 1.1156896551047564 0.8509796581854354 1.1086258181037891 0.7845809822848296 0.855567780436584 1.0 16.568023622069063 -5.992146782684672 1.1794635718925397 0.9144126049448827 1.5942629355790223 0.6161729568828236 0.19840263670402386 0.29744337482597183 0.8410645564414226 0.07254022908200836 0.14327957908631148 1.0182471830925898e-06 5.992146782684672 0.6798503306341396 SASSEEASES(ph)PTAR ddPTM_PC-9_AZD4547_30min_R2 2 SASSEEASESPTAR 14 0 A0A075B6Q3;Q5H9F3-3 A0A075B6Q3 BCORL1 BCL-6 corepressor-like protein 1 1 SAS(0.001)S(0.001)EEAS(0.013)ES(0.961)PT(0.024)AR;SASSEEASES(0.998)PT(0.001)AR 203.85 1.1669e-10 19597300.0 22170.0 15921.9 25862.0 34675.0 30475.0 25678.0 21008.8 27178.0 23323.0 23755.8 True False 29219.598835353103 21068.342805275526 25519.052982069403 26681.214473409636 26244.072286790895 24072.35060074529 22878.542500561613 22978.264588309772 24555.806165151796 22924.116672702774 1.274622671509379 0.9190470937692863 1.1131967851331253 1.1638928057446454 1.1448237095234037 1.0500884699042643 0.998011955147854 1.0023620502538917 1.0711778567412362 1.0 14.484578523556765 -6.9372733794886035 5.118029342547097 1.0186696708058076 1.1130852390444714 0.25738497678227146 0.08436983540470758 0.3175552725207283 16.48490264647531 0.030010954223189282 0.026173244489126384 1.1553847221987545e-07 6.9372733794886035 0.09441556823866382 SASSEEASES(ph)PTAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASSEEASESPTAR 14 0 A0A075B6Q3;Q5H9F3-3 A0A075B6Q3 BCORL1 BCL-6 corepressor-like protein 1 1 SASSEEAS(0.003)ES(0.976)PT(0.022)AR 128.73 2.478e-05 7867700.0 6666.1 4796.8 8277.9 8669.2 9893.8 8004.5 5867.3 9326.1 7682.6 7475.2 True False 7794.539068523549 5272.9946030531955 8475.276530110572 8183.49282992562 7955.180913237569 7584.729928883089 5311.506868426566 9081.29975681975 7794.943490948741 8830.394586349354 0.88269431137006 0.5971414472468266 0.9597845766951628 0.9267414666357311 0.9008862328230778 0.8589344286616704 0.6015027773093479 1.028413811865017 0.8827401102775989 1.0 13.108262190831452 -14.522878744035658 0.10732567927798214 1.5110576364954644 0.7520332605866364 0.12240380325524547 0.13276296867535678 386.59650045566184 2.765841032536663 43.18515945223266 1.8413478928509428 3.0000000085979392e-15 14.522878744035658 -0.759024375908828 SASSEEASES(ph)PTAR ddPTM_PC-9_Lapatinib_30min_R1 2 SASSEEASESPTAR 14 0 A0A075B6Q3;Q5H9F3-3 A0A075B6Q3 BCORL1 BCL-6 corepressor-like protein 1 1 SAS(0.002)S(0.002)EEAS(0.007)ES(0.978)PT(0.011)AR;SASSEEASES(1)PTAR 221.85 3.1358e-16 15147000.0 28761.0 24436.0 27883.0 23851.0 31196.0 28817.0 20139.8 21449.5 29937.0 18862.8 True False 28350.86286587856 24379.419943343375 25590.567371492583 25605.08210460357 29361.112613695776 27584.56408570799 21182.540299201773 22446.12207524955 26565.17980941431 22123.209846898888 1.2814986189652144 1.101983849181847 1.156729405388691 1.1573854916081607 1.3271633192871177 1.2468608432774344 0.9574804219547295 1.0145960839582202 1.2007832495038269 1.0 14.4332731003049 -7.251008842245466 24.906057976345434 1.0444312770818085 1.2071875784935067 0.48480011716573823 0.08512053597891164 637.6849923232977 1522667.3654685323 0.03411909931318101 0.026130697337282745 5.6103655319928463e-08 7.251008842245466 0.16275630141169817 SASSGAEGDVS(ph)SEREP ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SASSGAEGDVSSEREP 16 1 Q8TEA8 Q8TEA8 DTD1 D-tyrosyl-tRNA(Tyr) deacylase 1 1 SASSGAEGDVS(0.581)S(0.419)EREP;SASSGAEGDVS(0.642)S(0.357)EREP 132.81 2.5376e-05 21084000.0 60244.0 58045.0 66207.0 60857.0 65892.0 75806.0 64574.0 69462.0 59396.8 44060.0 True False 70442.1193267626 63807.32399395901 67785.62597144567 57447.37959105604 52980.9356096798 71830.5999111639 58457.08324472532 67638.69610107246 60265.36583229431 52047.72922123194 1.3534138833866165 1.2259386710752016 1.302374320372727 1.1037442065315197 1.0179298194640003 1.380090947019873 1.1231437782088445 1.2995513370731353 1.157886554015312 1.0 15.667547601427044 -14.522878745280336 0.20578032098397966 0.011631400396362963 1.2472050715536542 0.2766148367424406 0.10991095849842711 209.53174965035282 2.0772429904956673 85.62497187778077 0.2487006412734914 3.0000000000000132e-15 14.522878745280336 1.2355736711572913 SASSGAEGDVS(ph)SEREP ddPTM_PC-9_Lapatinib_30min_R1 1 SASSGAEGDVSSEREP 16 1 Q8TEA8 Q8TEA8 DTD1 D-tyrosyl-tRNA(Tyr) deacylase 1 1 SASSGAEGDVS(0.5)S(0.5)EREP 98.421 0.020655 0.0 15106.0 9749.8 12535.0 12295.0 14246.0 12544.0 9805.1 11185.0 13363.0 10001.0 True False 14890.585669898883 9727.224937125924 11504.420686499272 13199.215314917661 13408.078288713625 12007.522361492202 10312.760101277243 11704.695932850005 11857.918221371661 11729.659524505163 1.269481491665639 0.8292845087961992 0.9807974956531917 1.1252854601058417 1.1430918570741095 1.0236889089923316 0.8792037040574121 0.997871754793649 1.0109345626442563 1.0 13.517873516578538 -7.008612505377704 24.621972237147595 0.9689138834143372 1.0572985329214621 0.13875319324443613 0.11245696392432132 778.1186298472238 2224534.8657539566 0.041512976845639475 0.034819587891080646 9.80364314905294e-08 7.008612505377704 0.08838464950712499 SASSGAEGDVSS(ph)EREP ddPTM_PC-9_AZD4547_30min_R2 2 SASSGAEGDVSSEREP 16 1 Q8TEA8 Q8TEA8 DTD1 D-tyrosyl-tRNA(Tyr) deacylase 1 1 SASSGAEGDVS(0.021)S(0.979)EREP;SASSGAEGDVS(0.11)S(0.89)EREP 194.77 4.369899999999999e-11 67923000.0 119385.0 112275.0 158801.0 193086.0 165208.0 154536.0 126780.0 175181.0 131207.0 155878.0 True False 157346.94663773707 148565.6980927096 156695.19498126974 148573.00584896255 142271.72089765887 144872.83949048904 138063.1743945963 148110.80170890747 138142.3341556007 150420.75866557081 1.0460454263999903 0.9876675228251869 1.0417125692714317 0.9877161049246111 0.9458250454245506 0.9631173301856799 0.9178465500333699 0.9846433632089368 0.9183728055961435 1.0 17.198644152870436 -6.023427052421174 3.797386447522749 0.9530967293690515 1.0212708951266698 0.550270810273157 0.028308736162625865 0.15983778875175003 5.014848414931762 0.007804516606031369 0.01105075483690085 9.474863185282906e-07 6.023427052421174 0.06817416575761825 SASSGAEGDVSS(ph)EREP ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASSGAEGDVSSEREP 16 1 Q8TEA8 Q8TEA8 DTD1 D-tyrosyl-tRNA(Tyr) deacylase 1 1 SASSGAEGDVS(0.14)S(0.86)EREP 107.13 0.0045463000000000005 26298000.0 53682.0 57244.0 66001.0 76062.0 82753.0 62599.0 71477.0 66463.0 59946.0 50260.0 True False 62769.30233217038 62926.80600758359 67574.71415018645 71800.49273633116 66538.14369738103 59316.198240758626 64706.18111133327 64718.41667336945 60822.59684330994 59371.740142058945 1.0572252418740309 1.0598780810031578 1.1381629372576958 1.2093378527315166 1.1207039500303513 0.999064506090483 1.0898481492459307 1.0900542331842977 1.0244368229359544 1.0 15.857488777606816 -6.7299653175500955 24.11557063330128 1.049382104183045 1.1201835817756074 0.3638154584959614 0.04975637023583045 176.9763000992732 135599.26491654775 0.01783349384539136 0.01783141689184897 1.8622358475613963e-07 6.7299653175500955 0.0708014775925625 SASSGAEGDVSS(ph)EREP ddPTM_PC-9_Lapatinib_30min_R1 2 SASSGAEGDVSSEREP 16 1 Q8TEA8 Q8TEA8 DTD1 D-tyrosyl-tRNA(Tyr) deacylase 1 1 SASSGAEGDVS(0.027)S(0.973)EREP;SASSGAEGDVS(0.08)S(0.92)EREP 195.6 3.9284999999999997e-11 65442000.0 358734.0 278359.0 363960.0 288354.0 337203.0 309742.0 274046.0 278733.0 314213.0 247048.0 True False 353618.38737624115 277714.47683782584 334036.613726229 309560.5150807454 317369.3825066056 296495.05670386786 288234.7609626235 291683.9527448443 278823.02313042426 289749.9176292325 1.2204261877607694 0.9584626601799163 1.152844551119653 1.0683713652573414 1.09532173504434 1.0232791751239305 0.9947708124336802 1.006674842676182 0.962288532855459 1.0 18.14444872553598 -6.899982844747 2.355415544494632 0.9909786277409919 1.0939430185118222 0.3988923657858354 0.06308030192848338 0.31923641764345867 3.6033044292880554 0.023882264811887162 0.020208601582278666 1.2589751421301787e-07 6.899982844747 0.1029643907708303 SASSS(ph)WLEGTSTQAK ddPTM_PC-9_Lapatinib_30min_R1 1 SASSSWLEGTSTQAK 15 0 Q9BZL4-3;K7EL81;Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-3;Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 SAS(0.076)S(0.05)S(0.789)WLEGT(0.08)S(0.003)T(0.001)QAK 90.853 0.0040893 12313000.0 50131.0 44959.0 50006.0 29248.0 41957.0 47915.0 40088.0 36192.0 42616.0 30365.0 True False 49416.122747100526 44854.90019777274 45894.69970874215 31398.995488467815 39489.17175063579 45865.78714532039 42163.56048790952 37873.61244539177 37816.137313625295 35613.54979118078 1.3875652114672872 1.2594897296331986 1.2886864684325108 0.8816586853199159 1.1088243655063768 1.2878746267713654 1.183919062691997 1.0634607520862933 1.0618468963458945 1.0 15.120138623475428 -5.559917427649584 24.99827537440037 1.0991220685566299 1.311167903240492 0.49278163577879763 0.1054495380867172 151.58500370267578 102307.58797306322 0.030295795629948098 0.052473997732147074 2.7547524142496132e-06 5.559917427649584 0.21204583468386207 SASSSAAGS(ph)PGGLTSLQQQK ddPTM_PC-9_AZD4547_30min_R2 2 SASSSAAGSPGGLTSLQQQK 20 0 E5RJ10;E5RHB8;E5RJX6;E5RG91;Q8NEZ2-3;Q8NEZ2-2;Q8NEZ2 E5RJ10 VPS37A Vacuolar protein sorting-associated protein 37A 1 SAS(0.117)S(0.012)S(0.4)AAGS(0.47)PGGLTSLQQQK;SAS(0.002)S(0.08)S(0.273)AAGS(0.645)PGGLTSLQQQK 276.05 4.538199999999998e-202 8706500.0 34143.0 32539.0 43076.0 49289.0 48179.0 42532.0 37209.0 45358.0 39035.0 46012.0 True False 44999.763781482245 43056.59541517411 42504.784094641625 37926.18255745889 41490.177480075436 39872.46731641481 40520.52891661573 38348.96332314942 41098.310408468045 44401.13388496281 1.0134823110164348 0.9697183753623903 0.9572905098497178 0.8541714870552716 0.9344395930872113 0.8980056099404771 0.9126012191850508 0.8636933332041987 0.9256139835290711 1.0 15.438308899127646 -5.36152366934572 2.3845814276611432 0.9074510797930787 0.9983552549455399 0.3799343214307952 0.03985677750888425 0.27508958738774497 2.9740247960066064 0.010330905593911461 0.03004794300787282 4.3498705289334696e-06 5.36152366934572 0.09090417515246119 SASSSAAGS(ph)PGGLTSLQQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASSSAAGSPGGLTSLQQQK 20 0 E5RJ10;E5RHB8;E5RJX6;E5RG91;Q8NEZ2-3;Q8NEZ2-2;Q8NEZ2 E5RJ10 VPS37A Vacuolar protein sorting-associated protein 37A 1 SAS(0.004)S(0.104)S(0.104)AAGS(0.788)PGGLTSLQQQK 227.46 6.291799999999998e-102 0.0 13667.0 13277.0 10609.0 11720.0 13172.0 13439.0 13550.0 10882.0 8614.0 6662.4 True False 15980.553164445675 14595.052815363837 10861.958794856553 11063.366396752666 10591.041155993173 12734.235181992608 12266.44590649531 10596.359030432071 8739.963453913055 7870.24038047062 2.030503820963354 1.8544608690199995 1.380130500436765 1.405721536054418 1.3457074554258857 1.6180236646381991 1.5585859279385579 1.3463831494557776 1.1105078156952592 1.0 12.942191985250853 -1.5228787452803376 0.43153638743774014 1.2961599913043693 16.525519884039383 0.6618332395371529 0.17295301526581455 56.109061686641304 0.7030133241861533 0.1211226884614789 743.7250413008904 0.029999999999999995 1.5228787452803376 15.229359892735014 SASSSAAGSPGGLT(ph)SLQQQK ddPTM_PC-9_Lapatinib_30min_R1 1 SASSSAAGSPGGLTSLQQQK 20 0 E5RJ10;E5RHB8;E5RJX6;E5RG91;Q8NEZ2-3;Q8NEZ2-2;Q8NEZ2 E5RJ10 VPS37A Vacuolar protein sorting-associated protein 37A 1 SASSSAAGS(0.211)PGGLT(0.609)S(0.179)LQQQK 123.26 1.7504e-05 8487100.0 32504.0 31444.0 34034.0 31545.0 30424.0 32228.0 30070.0 26271.0 32335.0 23354.0 True False 32040.486999496443 31371.1933499136 31235.85589503922 33864.92453103516 28634.520135885406 30849.68356713733 31626.877466360012 27491.646567000666 28693.091797354846 27390.707782751077 1.1697575416314543 1.1453224793873045 1.1403814805658135 1.2363654418729966 1.0454100114169962 1.126282818677818 1.1546571821804694 1.0036851469867147 1.0475483884875705 1.0 14.74139892567569 -7.697425822601076 0.6959644283686485 0.9953929041211733 1.1610080173244886 0.5625669700809335 0.04920589259653909 0.5160683961795169 0.48673495396551675 0.04533508814695027 0.02319858475004706 2.007123877045963e-08 7.697425822601076 0.16561511320331523 SAST(ph)DLGTADVVLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SASTDLGTADVVLGR 15 0 Q9Y2K5-2;H7C0E9;A0A0U1RRA6;B5MCU0;B5MCG9;Q9Y2K5;Q9Y2K5-3 Q9Y2K5-2 R3HDM2 R3H domain-containing protein 2 1 S(0.103)AS(0.238)T(0.66)DLGTADVVLGR 194.77 3.2009e-09 8672700.0 15446.0 15432.0 14839.0 19327.0 17098.0 16002.0 13290.0 11919.0 9293.8 12671.0 True False 18060.702727594045 16963.98697346499 15192.818037220883 18244.170848979426 13747.76963901999 15162.826950088978 12031.074988732307 11606.138879224382 9429.70424285781 14968.151996419188 1.2066087204295282 1.1333387700447766 1.0150096044491959 1.218865953081179 0.9184680675549561 1.0130059444690542 0.803778248083697 0.7753888978412902 0.6299845328343583 1.0 13.869608493385547 -6.860209008804889 1.1176124363955982 0.7736546149783502 1.1364147469101855 0.6223318046549046 0.11216473906937376 0.30043517239367673 0.7894781195471502 0.060215005505468495 0.04938024140024727 1.3797200999317881e-07 6.860209008804889 0.3627601319318353 SAST(ph)DLGTADVVLGR ddPTM_PC-9_Lapatinib_30min_R1 1 SASTDLGTADVVLGR 15 0 Q9Y2K5-2;H7C0E9;A0A0U1RRA6;B5MCU0;B5MCG9;Q9Y2K5;Q9Y2K5-3 Q9Y2K5-2 R3HDM2 R3H domain-containing protein 2 1 S(0.019)AS(0.301)T(0.68)DLGTADVVLGR 125.47 6.4386e-05 16192000.0 34787.0 29589.0 30388.0 37221.0 34615.0 32852.0 29028.0 35827.0 45907.0 79154.0 True False 34290.9310008455 29520.488488442756 27889.615941072214 39958.356505616124 32579.01375570842 31446.996541752407 30530.927804905154 37491.65321289378 40736.47023785894 92835.66343392468 0.36937239130360605 0.31798650859487654 0.30041920216278206 0.43042032584876483 0.35093209388110175 0.33873831864340204 0.3288706804646836 0.40384968261231075 0.43880195100725405 1.0 16.502391512222225 -9.285364520913772 0.9694338337178577 1.0043383669497663 0.3474850947399547 0.968514956703349 0.03474570559134505 0.6038577246701953 0.6396944277820434 0.040332779897092816 0.011095282311427273 5.183647717794923e-10 9.285364520913772 -0.6568532722098116 SASVVSSDSISTS(ph)ADNFSPDLR ddPTM_PC-9_AZD4547_30min_R2 1 SASVVSSDSISTSADNFSPDLR 22 0 Q13614 Q13614 MTMR2 Myotubularin-related protein 2 1 SASVVSS(0.003)DS(0.014)IS(0.092)T(0.092)S(0.415)ADNFS(0.384)PDLR 130.09 1.1273e-05 12767000.0 26110.0 28487.0 44585.0 54722.0 45433.0 41561.0 37541.0 57654.0 39191.0 52122.0 True False 34412.436878262066 37694.86565635281 43993.77376867851 42106.68834647212 39125.41218066518 38962.18409991339 40882.07627344651 48744.89905712017 41262.55624998775 50297.224644702066 0.68418162475863 0.7494422589442677 0.8746759702836305 0.8371572913597594 0.7778841170073657 0.7746388468775559 0.8128097834867857 0.9691369534095078 0.820374415118629 1.0 15.618191175170882 -11.561628563007535 0.03156898034288063 1.9905165545332342 5.929932509487305e-12 0.5809401252616397 0.059410877758429674 552.1376999712743 2.390719848563374 97.16894847352701 57.527119884741325 2.743919948122193e-12 11.561628563007535 -1.9905165545273042 SASVVSSDSISTSADNFS(ph)PDLR ddPTM_PC-9_AZD4547_30min_R2 1 SASVVSSDSISTSADNFSPDLR 22 0 Q13614 Q13614 MTMR2 Myotubularin-related protein 2 1 SASVVSSDSISTSADNFS(1)PDLR 298.96 1.9646999999999994e-132 12658000.0 15384.0 17440.0 29046.0 35425.0 39663.0 33874.0 33238.0 38238.0 28453.0 36687.0 True False 20275.79199292163 23077.138942211997 28660.83106168075 27258.31356079411 34156.47708321535 31755.85342509722 36196.11760946207 32329.19572182611 29956.96749204923 35402.599296653716 0.5727204328422889 0.651848717345262 0.8095685523404434 0.7699523227767796 0.9648013920391391 0.8969921434017081 1.0224141257583692 0.9131870643430945 0.8461798875564707 1.0 15.111567667957285 -5.242565269881024 0.777747043907326 0.9441431960040806 0.47459929862238787 0.8290951644973094 0.057808607363222866 0.6057267773931936 0.4332405139042675 0.024466658567674705 0.22053565521573743 5.720509749622699e-06 5.242565269881024 -0.4695438973816927 SASVVSSDSISTSADNFS(ph)PDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SASVVSSDSISTSADNFSPDLR 22 0 Q13614 Q13614 MTMR2 Myotubularin-related protein 2 1 SASVVSSDSISTS(0.008)ADNFS(0.991)PDLR;SASVVSSDSIS(0.013)T(0.013)S(0.009)ADNFS(0.965)PDLR 189.98 9.3493e-16 13997800.0 34642.0 39926.0 52228.0 56464.0 51167.0 44202.0 57803.0 50292.0 45749.0 39653.0 True False 40506.206389312 43889.5894182584 53473.313595793006 53300.505138757864 41141.193655382835 41883.9693068262 52327.48138252015 48971.88828877868 46417.99257639523 46841.775007024735 0.8647453343353746 0.9369753689239231 1.1415731702689267 1.1378839749510887 0.878301337838137 0.8941584579266044 1.1171114112279634 1.045474649101886 0.9909528955602994 1.0 15.515508125442219 -5.01404179690979 15.189127496675267 1.0255959430378834 0.8827850863799854 0.2636965814878288 0.08716754188213297 4.986023936879497 5408.438904802556 0.02380105366449468 0.07061181274059575 9.681846727729151e-06 5.01404179690979 -0.14281085665789794 SASVVSSDSISTSADNFS(ph)PDLR ddPTM_PC-9_Lapatinib_30min_R1 2 SASVVSSDSISTSADNFSPDLR 22 0 Q13614 Q13614 MTMR2 Myotubularin-related protein 2 1 SASVVS(0.001)S(0.17)DS(0.001)IS(0.021)T(0.021)S(0.154)ADNFS(0.632)PDLR;SASVVSS(0.001)DSIS(0.021)T(0.021)S(0.283)ADNFS(0.673)PDLR 163.15 1.5180999999999998e-07 27454000.0 101999.0 93578.0 101036.0 91640.0 88870.0 91700.0 86521.0 87337.0 101550.0 76754.0 True False 100544.47555567414 93361.325890415 92729.21009023854 98379.51130207836 83642.84132514245 87778.20476314057 91000.63402949562 91394.99585939368 90112.36963109266 90020.82663172355 1.1169023804569467 1.0371080713617247 1.0300861873841152 1.092852787328318 0.929149891805887 0.975087744108843 1.010884230176873 1.0152650145425999 1.001016909117527 1.0 16.457971192129087 -1.5228800039577721 0.5268568667937251 0.9952845142145059 5.444597594265437 0.4759200843637452 0.03707061059739151 113.59794950084543 1.1174390025984897 0.020125114873062754 566.5050294432926 0.02999991305376906 1.5228800039577721 4.449313080050931 SAT(ph)ASPQQPQAQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SATASPQQPQAQQR 14 0 Q9BX66-4;Q9BX66-9;Q9BX66-8;Q9BX66-10;Q9BX66-6;Q9BX66-5;Q9BX66-12;A0A0U1RQI5 Q9BX66-4 SORBS1 Sorbin and SH3 domain-containing protein 1 1 S(0.087)AT(0.909)AS(0.005)PQQPQAQQR 230.67 1.4189e-20 1986000.0 3045.5 2584.7 3861.4 4262.5 3321.3 3546.1 3633.0 3790.8 1076.9 2661.9 True False 3561.0429986331537 2841.29193431279 3953.470420441048 4023.6859442114524 2670.515107151542 3360.1362734477243 3288.8559393577475 3691.2955166846064 1092.6476252053596 3144.4813984111934 1.1324738637132457 0.9035804555079908 1.2572726372108962 1.2796024000156252 0.8492704420197457 1.068582016463985 1.0459136253817567 1.1738964391869835 0.3474810268419587 1.0 11.618606385825839 -8.238497657694118 24.89227661789759 0.6737403809221508 1.0845332568641843 0.4197317912141256 0.1951676159340761 588.1354839697409 638142.1882610848 0.1250590496638722 0.04719992782915369 5.7743398701415056e-09 8.238497657694118 0.4107928759420335 SAT(ph)FPNAGPR ddPTM_PC-9_AZD4547_30min_R2 2 SATFPNAGPR 10 0 Q86X27;Q86X27-3 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 S(0.036)AT(0.964)FPNAGPR;S(0.229)AT(0.771)FPNAGPR 150.09 0.00038930000000000003 112263000.0 77455.0 86536.0 79164.0 120282.0 121475.0 82525.0 87962.0 97278.0 85772.0 95217.0 True False 102084.07883591657 114507.0696962877 78114.23363516132 92552.84323837503 104610.29306112979 77364.69870420212 95790.44759502682 82245.92032605782 90305.73281299154 91883.48181179941 1.111016657433711 1.2462204026054118 0.8501444666099942 1.00728489401334 1.138510328498414 0.8419870163678013 1.0425208721544734 0.8951110548304889 0.9828288070097354 1.0 16.487517906459466 -5.252219010324343 24.989485713557325 0.9714491591188545 1.1786185382749959 0.46074513992553745 0.09035059461036259 555.0677153889819 1504362.8482987948 0.02225480280500042 0.0571467752105363 5.5947539254926715e-06 5.252219010324343 0.2071693791561413 SAT(ph)FPNAGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SATFPNAGPR 10 0 Q86X27;Q86X27-3 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 S(0.298)AT(0.702)FPNAGPR 120.86 0.0016409000000000003 59624000.0 48444.0 46771.0 46850.0 44705.0 74445.0 58804.0 53163.0 48876.0 48275.0 47834.0 True False 56644.61238738611 51414.115781229346 47967.08167961443 42200.32378556554 59858.03665790396 55720.214721474294 48127.01577321111 47593.056788402646 48980.93054767269 56505.925546264356 1.00245437694863 0.9098889237578087 0.8488858684447398 0.7468300603449797 1.0593231785734587 0.9860950720266185 0.8517162635236725 0.8422666530687251 0.8668282144599054 1.0 15.786114544563254 -10.974166014765848 3.2310520276749823 1.0016813180980588 0.8996432897911907 0.10223904826664709 0.08731596462090221 62888695.108642206 75812501.1100463 952190.0528146748 0.022943058824289504 1.0612897876974702e-11 10.974166014765848 -0.10203802830686814 SAT(ph)FPNAGPR ddPTM_PC-9_Lapatinib_30min_R1 1 SATFPNAGPR 10 0 Q86X27;Q86X27-3 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 S(0.053)AT(0.947)FPNAGPR 102.05 0.0082321 69648000.0 50680.0 45925.0 49144.0 41098.0 52812.0 63392.0 42396.0 36933.0 40448.0 35535.0 True False 49957.29390642623 45818.66348412357 45103.57002132595 44120.48401890898 49705.70199238689 60680.87193396953 44591.057434778806 38649.042010545294 35892.320303677385 41677.17740258882 1.1986726793864664 1.0993705989618552 1.08221268407021 1.0586245702946377 1.1926359962490973 1.4559736459072268 1.0699154840560048 0.9273430788560207 0.8611984433822981 1.0 15.346969953586743 -7.620318521884101 4.36572651824177 0.9229501839910147 1.1744764242063963 0.5131086786556593 0.10911065181827108 0.19221263934508934 6.5396438740991245 0.05912629865841196 0.032735519282068165 2.3970742030241615e-08 7.620318521884101 0.2515262402153816 SAT(ph)PEPVTDNR ddPTM_PC-9_AZD4547_30min_R2 2 SATPEPVTDNR 11 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 S(0.01)AT(0.983)PEPVT(0.007)DNR;S(0.008)AT(0.976)PEPVT(0.016)DNR 116.74 0.0030107 11062700.0 61763.0 93066.0 78481.0 65961.0 87116.0 115259.0 96090.0 119606.0 99423.0 72581.0 True False 81402.34924979323 123147.7644951778 77440.29066142565 50754.7105372912 75021.44713161873 108051.83650951408 104641.8238490046 101123.64097245506 104678.29680392265 70039.9612819371 1.1622272165759524 1.7582500367106415 1.105658673192286 0.7246536064316835 1.071123480917262 1.5427169651702823 1.494030292617982 1.4437992129292376 1.494551037550596 1.0 16.095890665799892 -6.759398367368964 24.998334861463718 1.4289451314469301 1.169683402044891 0.14261645184963434 0.27641091755191594 107.75508254701192 1319788.6099970615 0.10024155237030406 0.09551355172137377 1.7402098904486578e-07 6.759398367368964 -0.2592617294020392 SAT(ph)PEPVTDNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SATPEPVTDNR 11 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 S(0.01)AT(0.974)PEPVT(0.016)DNR;S(0.09)AT(0.848)PEPVT(0.062)DNR 99.539 0.011052 7785400.0 29971.0 50897.0 36558.0 25356.0 39191.0 23771.1 30107.0 21689.8 21218.8 20620.5 True False 35044.498345767264 55949.717793445285 37429.68136698705 23935.385525261147 31511.804884947484 22524.50166937008 27255.047004195883 21120.46573224273 21529.08480797428 24358.833418211823 1.4386772036285749 2.2968964413383857 1.5365958100030703 0.9826162490756193 1.293650001374358 0.9246954188097404 1.1188978772611793 0.8670557152565469 0.8838307006885687 1.0 14.572157421576076 -5.607349845875501 3.7822269459996307 1.0177809622580982 1.8818293932033066 0.7051746248931529 0.227202326241324 0.10770478113606753 2.9776696958250994 0.05984933270013229 0.11153543933284207 2.4697338496325334e-06 5.607349845875501 0.8640484309452083 SAT(ph)PEPVTDNR ddPTM_PC-9_Lapatinib_30min_R1 1 SATPEPVTDNR 11 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 S(0.002)AT(0.991)PEPVT(0.008)DNR 105.36 0.0062794 4319800.0 17230.0 26838.0 29074.0 23136.0 33506.0 28563.0 33987.0 33572.0 34753.0 26415.0 True False 16984.29704040497 26775.858259921813 26683.647948885508 24837.49861943349 31535.242955330512 27341.427073605057 35746.680560331835 35131.877680611535 30838.75117468604 30980.797554224962 0.5482201357365882 0.8642727229038135 0.8612963530774747 0.8017062367733109 1.0178964211665344 0.8825281862337468 1.153833451116462 1.133988807716168 0.995415018632419 1.0 14.919086664177721 -4.124415090315842 0.4042237663222922 1.0749551016370382 6.780151731842796e-11 0.7006843164507492 0.0918667678726244 5.433586464788927 0.46554048936152953 0.0726290354065637 3.1362026287629488 7.509048505079306e-05 4.124415090315842 -1.0749551015692367 SAT(ph)PTPTVIAR ddPTM_PC-9_AZD4547_30min_R2 1 SATPTPTVIAR 11 0 Q92618;A0A087WUJ4 Q92618 ZNF516 Zinc finger protein 516 1 SAT(0.932)PT(0.056)PT(0.012)VIAR 92.943 0.013481 0.0 18629.0 20028.0 28923.0 36518.0 25162.0 27494.0 21928.0 36296.0 26018.0 24605.0 True False 24552.6344927286 26501.65933111364 28539.462122047524 28099.339297475763 21668.690627735283 25774.79583366663 23879.549519835236 30687.287199105587 27393.25836320026 23743.58643917913 1.0340743828074122 1.11616075351546 1.2019861529829694 1.1834496599515074 0.9126123672698377 1.0855477077858726 1.005726307649621 1.2924453210854745 1.1537119058811955 1.0 14.535250248279267 -11.235158515718469 7.78312936359766 0.9993635338112808 1.110443292559658 0.09293649407266258 0.10261303429289494 0.0011887151634614413 4.394339458529515e-05 0.10421534361936452 0.025134356713010286 5.818907912351091e-12 11.235158515718469 0.11107975874837706 SAT(ph)PTPTVIAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SATPTPTVIAR 11 0 Q92618;A0A087WUJ4 Q92618 ZNF516 Zinc finger protein 516 1 S(0.28)AT(0.697)PT(0.018)PT(0.006)VIAR 92.11200000000001 0.014438 0.0 34377.0 36925.0 39450.0 46503.0 48400.0 45429.0 38508.0 34478.0 42826.0 34889.0 True False 40196.347123300584 40590.66997117647 40390.63761495815 43897.587674760194 38916.36744230714 43046.62326681613 34860.24346622301 33572.989032460646 43452.24923116793 41214.09951882794 0.9753057228616043 0.9848733915109156 0.9800198982027107 1.0651109253207474 0.944248883189329 1.0444635153838806 0.8458329521502154 0.8145996012147109 1.0543054376650285 1.0 15.330850353513076 -7.252667095958982 24.987397959086245 0.9132344631838524 0.9980145491243654 0.1726573999330724 0.07229346376371981 925.5575465215123 2636407.621191972 0.027214790198132152 0.020736560291925058 5.588984485299787e-08 7.252667095958982 0.084780085940513 SAT(ph)PTPTVIAR ddPTM_PC-9_Lapatinib_30min_R1 2 SATPTPTVIAR 11 0 Q92618;A0A087WUJ4 Q92618 ZNF516 Zinc finger protein 516 1 S(0.008)AT(0.935)PT(0.056)PT(0.001)VIAR;S(0.084)AT(0.894)PT(0.009)PT(0.013)VIAR 92.943 0.013481 4836700.0 73872.0 74911.0 80960.0 60730.0 69197.0 69142.0 65885.0 71532.0 76881.0 58471.0 True False 72818.57173353447 74737.54818201804 74303.7813146377 65196.28678934114 65126.96850653628 66184.95783787419 69296.20292221915 74855.63786040465 68221.85218717913 68577.63444228999 1.0618414053755871 1.0898239460988086 1.0834987517273789 0.9506931424443585 0.949682342299842 0.9651099571474822 1.010478175366837 1.091545931398345 0.9948119783074428 1.0 16.065450519500487 -5.742543327945708 24.92832125691681 0.9959908757368472 1.0795316763223852 0.49624002975768755 0.0386558258615879 226.87495426206362 299299.0051547159 0.011939544317888314 0.020634403312419513 1.8090754165223967e-06 5.742543327945708 0.08354080058553803 SAT(ph)PVNCEQPDILVSSTPINEGQTVLDK ddPTM_PC-9_AZD4547_30min_R2 1 SATPVNCEQPDILVSSTPINEGQTVLDK 28 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 S(0.313)AT(0.687)PVNCEQPDILVSSTPINEGQTVLDK 130.38 6.6725e-12 14061000.0 26940.0 25486.0 33201.0 41038.0 41339.0 38357.0 31811.0 41311.0 35884.0 39823.0 True False 35506.35961318959 33723.85109410635 32760.733046851987 31577.323130779656 35599.79341308117 35958.53072641124 34642.11737392734 34927.33418234105 37780.75498136206 38428.808891177854 0.9239516039577491 0.8775669105333206 0.8525045139864563 0.8217096506998138 0.9263829517561201 0.9357180657937666 0.901462167927879 0.9088841207971804 0.9831362478173356 1.0 15.229900640014131 -8.065413616436764 0.5734219775030782 1.0033785429117703 0.874411304903175 0.588421731068129 0.03315127997495613 0.5950339819239281 0.4547012958095091 0.0359900951017319 0.018845565860432636 8.601741432466158e-09 8.065413616436764 -0.12896723800859533 SAT(ph)TSGAPGVEK ddPTM_PC-9_AZD4547_30min_R2 1 SATTSGAPGVEK 12 0 H7C1F9;Q2PPJ7-3;Q2PPJ7-2;Q2PPJ7;A0A3B3IS41 H7C1F9 RALGAPA2 Ral GTPase-activating protein subunit alpha-2 1 S(0.001)AT(0.949)T(0.048)S(0.003)GAPGVEK 83.53 0.027339 0.0 23674.0 18624.0 21462.0 37604.0 37056.0 30846.0 24462.0 25465.0 25765.0 30007.0 True False 31201.839550209734 24643.843787830046 21177.399856978307 28934.97877600853 31911.414033119712 28917.194743772485 26639.070610826773 21529.96937748578 27126.88529971 28956.464063419953 1.0775431517422844 0.8510653695097413 0.7313531034243659 0.9992580141220155 1.1020480250360638 0.9986438496233013 0.9199697363767322 0.7435289519580571 0.9368162231513198 1.0 14.821597822107988 -10.187224595858572 4.202499717054179 0.9999997061654684 0.9243101856960196 0.02983821426062061 0.11902440315464288 91254420.35228369 237517745.9456509 297.65052920451933 0.03280920617732223 6.497935619963174e-11 10.187224595858572 -0.07568952046944877 SAT(ph)TTGSPGTEK ddPTM_PC-9_Lapatinib_30min_R1 1 SATTTGSPGTEK 12 0 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 S(0.016)AT(0.941)T(0.032)T(0.009)GS(0.002)PGTEK 222.72 3.3817e-12 29382000.0 132050.0 129510.0 116910.0 116720.0 118690.0 97114.0 96990.0 98761.0 102580.0 60951.0 True False 130166.9427849956 129210.12755207063 107298.1110856504 125303.97816650593 111708.88755351816 92960.66060379108 102011.66762428531 103349.79660475648 91026.36018471196 71486.29913789757 1.8208655973909442 1.8074810013989309 1.5009604970411405 1.7528390709497168 1.5626615015841139 1.3003982822564268 1.427010054437202 1.4457287319545526 1.273339944611225 1.0 16.125379145078885 -1.5228787452817398 0.07982001293674171 0.5345213553892324 4.036800461926826 0.8452296196952227 0.09745590380967165 73.92620669298044 0.4319578053103187 2.8702029225573478 28.57170624497728 0.029999999999903135 1.5228787452817398 3.5022791065375936 SATAS(ph)PQQPQAQQR ddPTM_PC-9_Lapatinib_30min_R1 2 SATASPQQPQAQQR 14 0 Q9BX66-4;Q9BX66-9;Q9BX66-8;Q9BX66-10;Q9BX66-6;Q9BX66-5;Q9BX66-12;A0A0U1RQI5 Q9BX66-4 SORBS1 Sorbin and SH3 domain-containing protein 1 1 S(0.011)AT(0.223)AS(0.766)PQQPQAQQR;SAT(0.037)AS(0.962)PQQPQAQQR 193.98 1.5460000000000002e-07 3496800.0 7605.8 8430.3 7755.4 5967.3 6914.0 7063.200000000001 7261.7 7034.2 9185.0 4673.0 True False 7497.339897267101 8410.78015830609 7117.780948709729 6406.155148329251 6507.332113447006 6761.123401123389 7637.675294229014 7361.0346116096125 8150.488577662108 5480.7218236188955 1.3679475329248953 1.5346117589950024 1.2986940731120507 1.1688524531061304 1.1873129713323498 1.2336191506722103 1.3935528092877905 1.3430775814761484 1.4871195510303017 1.0 12.420150196602792 -5.3808109790103416 6.31829061888587 1.2721182354730738 1.449756190680937 0.24442842968506828 0.13170158407849622 0.3322968691025626 15.723991346372449 0.03488350613072357 0.0735849290774352 4.160916695431711e-06 5.3808109790103416 0.1776379552078633 SATDGNTS(ph)TTPPTSAK ddPTM_PC-9_AZD4547_30min_R2 1 SATDGNTSTTPPTSAK 16 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 SAT(0.002)DGNT(0.214)S(0.337)T(0.337)T(0.108)PPT(0.001)SAK 112.57 0.00033174 97382000.0 275850.0 230870.0 320670.0 391550.0 363290.0 370410.0 322760.0 408230.0 304040.0 327950.0 True False 363564.5619635611 305494.21259108296 316417.70627794426 301284.1968871968 312853.4543418626 347248.20414448425 351485.0147310295 345147.4336921665 320110.93369003764 316468.57032021193 1.1488172793768938 0.9653224403357819 0.9998392761650353 0.952019331911377 0.9885766982335987 1.0972596861455424 1.1106474629546528 1.0906215215714359 1.0115094000207991 1.0 18.271702701753284 -6.755809416750499 24.983088956856072 1.0707114513558424 1.0044947796195627 0.13968060283045303 0.06049238848739059 214.3952534002259 951383.0895258284 0.020167742970452172 0.019631248098479916 1.7546503334015515e-07 6.755809416750499 -0.06621667173627976 SATDGNTS(ph)TTPPTSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SATDGNTSTTPPTSAK 16 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 SATDGNT(0.115)S(0.345)T(0.345)T(0.195)PPTSAK;SATDGNT(0.087)S(0.345)T(0.345)T(0.218)PPT(0.004)S(0.001)AK;SATDGNT(0.158)S(0.39)T(0.39)T(0.061)PPTSAK 136.34 1.0105e-05 171571300.0 278849.0 315965.0 322040.0 347219.0 328467.0 326321.0 353468.0 356334.0 342576.0 271835.0 True False 326052.6281812034 347331.9170600617 329718.6549435018 327765.44512918557 264106.24927008885 309208.15230471076 319984.9521532899 346980.610067081 347585.52590988076 321116.5336553235 1.0153716610904193 1.08163822368884 1.026788160641431 1.0207056030350614 0.8224623200298129 0.9629157016144337 0.9964761032726887 1.080544206545027 1.0824279956975627 1.0 18.29273742292765 -10.12764644804605 10.4450030464622 1.0000027845158397 1.0076329484021478 0.0007739858394775201 0.07307332244833951 0.0 0.0 0.07805753734151916 0.018931733607922253 7.453384947329476e-11 10.12764644804605 0.007630163886308106 SATDGNTS(ph)TTPPTSAK ddPTM_PC-9_Lapatinib_30min_R1 1 SATDGNTSTTPPTSAK 16 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 SATDGNT(0.094)S(0.302)T(0.302)T(0.302)PPTSAK 113.43 0.00023530000000000003 102670000.0 383390.0 317930.0 361700.0 301460.0 361480.0 321390.0 261210.0 311800.0 330770.0 213480.0 True False 377922.78829488513 317193.8526185613 331962.422202377 323630.37404107954 340218.457097024 307644.89889668213 274734.175689654 326287.36628186295 293515.1994374844 250379.73355578003 1.5093984761777488 1.2668511469116022 1.3258358313909693 1.29255818530129 1.35880988555022 1.2287132609642484 1.0972700217705451 1.3031700355618923 1.1722801812635308 1.0 17.93375826561367 -1.522878750004949 0.04077382967221422 0.29464141771008684 2.851018489239921 0.6820760678444546 0.0760293711129403 450.25759768459136 1.4023683027551812 23.839420584996127 78.97130167971656 0.029999999673635407 1.522878750004949 2.556377071529834 SATDGNTST(ph)TPPT(ph)SAK ddPTM_PC-9_Lapatinib_30min_R1 1 SATDGNTSTTPPTSAK 16 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 2 SATDGNT(0.197)S(0.157)T(0.309)T(0.244)PPT(0.598)S(0.494)AK 82.663 0.031484 3301700.0 22502.0 20832.0 17930.0 20487.0 19879.0 20705.0 13509.0 17389.0 17011.0 12588.0 True False 22181.117353638587 20783.764783914256 16455.86461180152 21993.682322628556 18709.75630361772 19819.495415712387 14208.429919955355 18196.956421665494 15095.042046228646 14763.819027544338 1.5023969958082022 1.4077499016439254 1.1146075809450382 1.4897014303410057 1.2672707697589347 1.3424368978470849 0.9623817450923224 1.2325372173497977 1.0224347791087358 1.0 13.849778338036417 -7.183744144255191 0.5335086802708077 0.9960387446944731 1.4122610361867605 0.5414536358923681 0.12990605405377662 0.7442836116604514 0.4493461856705931 0.12083293726366258 0.10722306751183705 6.550219532561466e-08 7.183744144255191 0.4162222914922874 SATDGNTST(ph)TPPTSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SATDGNTSTTPPTSAK 16 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 SATDGNT(0.074)S(0.345)T(0.578)T(0.004)PPTSAK 168.1 9.986200000000001e-05 8489500.0 50804.0 46871.0 54487.0 58118.0 61350.0 57747.0 62214.0 57090.0 57446.0 44167.0 True False 59404.11377526142 51524.04312035237 55786.17672309823 54861.83688109824 49328.90790465999 54718.64566221646 56320.6395296457 55591.44799185502 58286.03907284527 52174.1274742204 1.1385741679075212 0.9875401010934157 1.0692306594041763 1.0515142185790431 0.9454668490437861 1.0487697314967717 1.0794744877616615 1.0654983740614186 1.1171444908521913 1.0 15.671046948453663 -7.006286935590855 24.968722092114735 1.0700067673238003 1.0339749862622134 0.04650860221985764 0.054510861913061676 748.9188129377472 2974363.0730822403 0.019136955318069464 0.01630742316770356 9.856280722892987e-08 7.006286935590855 -0.03603178106158689 SATDGNTST(ph)TPPTSAKK ddPTM_PC-9_AZD4547_30min_R2 1 SATDGNTSTTPPTSAKK 17 1 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 SATDGNT(0.005)S(0.161)T(0.416)T(0.416)PPTSAKK 60.669 0.029494 10265000.0 17912.0 12338.0 18688.0 29753.0 29833.0 19832.0 18692.0 21280.0 15869.0 20997.0 True False 23607.643407255087 16326.017217259847 18440.18490947772 22893.905529267668 25691.20290506424 18591.9019048984 20355.551788797897 17991.6649657529 16707.80294279441 20261.901420989412 1.1651247786054177 0.8057495137325877 0.9100915321982287 1.1298991665980445 1.2679561691308292 0.9175793287415243 1.0046219930628757 0.8879554091165027 0.8245920555850058 1.0 14.306481945688278 -7.51597094959441 2.008463630506955 0.8939674224247808 1.033147543833259 0.15403320995578085 0.13364996134496823 0.6856755111117029 5.45639216637769 0.0848220582086804 0.043718260328468615 3.048098873284704e-08 7.51597094959441 0.13918012140847813 SATDGNTST(ph)TPPTSAKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SATDGNTSTTPPTSAKK 17 1 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 S(0.001)AT(0.002)DGNT(0.039)S(0.193)T(0.711)T(0.052)PPT(0.001)S(0.001)AKK 63.827 0.020531 7320300.0 22043.0 11842.0 16952.0 23582.0 26726.0 29905.0 25287.0 25821.0 25961.0 22395.0 True False 25774.444530904795 13017.595498948454 17356.19997081801 22260.776993875552 21489.232154196277 28336.729155256242 22891.63229797394 25143.226109610936 26340.630511613283 26455.036221277533 0.9742736436011626 0.49206492820745135 0.6560641167014764 0.8414570597325972 0.8122926755591698 1.07112796664649 0.865303381424306 0.9504135960845322 0.995675465771155 1.0 14.691254772581857 -6.248494636777532 1.7295516559646356 0.9633225207053576 0.6938314416873448 0.42927210447654685 0.12710818476347796 0.3269427906092196 1.9320593371404504 0.04391787860587659 0.05913546527295451 5.642939099233732e-07 6.248494636777532 -0.26949107901801284 SATDGNTST(ph)TPPTSAKK ddPTM_PC-9_Lapatinib_30min_R1 1 SATDGNTSTTPPTSAKK 17 1 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 SATDGNTS(0.013)T(0.959)T(0.028)PPTSAKK 112.58 0.00021274 14206000.0 121770.0 59441.0 73199.0 56566.0 58157.0 54338.0 39318.0 36320.0 66468.0 34211.0 True False 120033.53747011692 59303.36801654417 67180.86077631134 60726.05233864434 54736.319601061216 52014.090408064694 41353.69365554849 38007.559792678774 58981.673900930306 40124.32576670794 2.9915402982225676 1.477990393193087 1.6743174992376526 1.5134472960796794 1.364167959339947 1.2963231011154326 1.0306389668947558 0.9472448213501075 1.4699729596420716 1.0 15.292189529511509 -2.033072884711155 0.8336187168956528 1.215066444648194 199.9999998030497 0.8379631252959332 0.22365059617139751 89.78763858284071 0.7026468923455877 0.079166247327946 33229.68257267967 0.009266742928379222 2.033072884711155 198.7849333584015 up SATDGNTSTT(ph)PPTSAK ddPTM_PC-9_AZD4547_30min_R2 3 SATDGNTSTTPPTSAK 16 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 SATDGNT(0.077)S(0.086)T(0.303)T(0.532)PPTS(0.002)AK;SAT(0.003)DGNT(0.153)S(0.14)T(0.162)T(0.525)PPT(0.016)S(0.002)AK;SATDGNT(0.041)S(0.138)T(0.138)T(0.472)PPT(0.074)S(0.138)AK 125.41 7.7932e-05 94136000.0 506036.0 388042.0 530392.0 639304.0 548680.0 571197.0 521776.0 608440.0 522109.0 554503.0 True False 666944.9217973279 513468.98792510503 523358.65552802396 491922.3399483397 472505.25290620053 535479.9612934772 568213.0531859533 514419.5785602777 549706.6158333513 535090.0187475767 1.2464163008653548 0.9595936570204064 0.9780759072146197 0.919326324007548 0.8830388090813932 1.0007287419541355 1.0619017983476944 0.9613701630322316 1.0273161460196658 1.0 19.029422092447895 -4.759554573545479 24.98090112531132 0.9743279981083719 1.2464166470131544 0.734786358259554 0.0485704915245238 26.717253855765165 354008.8262192587 0.013042195598299928 0.08208794022449083 1.7395840877627066e-05 4.759554573545479 0.27208864890478246 SATDGNTSTT(ph)PPTSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SATDGNTSTTPPTSAK 16 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 SATDGNT(0.011)S(0.026)T(0.117)T(0.406)PPT(0.406)S(0.034)AK;SATDGNT(0.007)S(0.024)T(0.081)T(0.886)PPT(0.001)SAK 163.34 0.00015941 64029000.0 760495.0 804843.0 745248.0 922705.0 923267.0 903994.0 938112.0 891719.0 797565.0 744985.0 True False 889231.7830390788 884742.4940179152 763017.5386887774 871008.8302999712 742359.4590776154 856586.9632495139 849247.240017278 868312.3211043789 809227.879280262 880044.8832019855 1.0104391264723538 1.0053379218555738 0.8670211636395045 0.9897322817568835 0.8435472704262416 0.9733446323020236 0.9650044630989134 0.9866682230400359 0.9195302361578873 1.0 19.747217579006822 SATDGNTSTT(ph)PPTSAK ddPTM_PC-9_Lapatinib_30min_R1 3 SATDGNTSTTPPTSAK 16 0 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 SATDGNT(0.014)S(0.021)T(0.218)T(0.705)PPT(0.032)S(0.01)AK;SATDGNT(0.034)S(0.058)T(0.069)T(0.826)PPT(0.011)S(0.002)AK;SATDGNT(0.004)S(0.043)T(0.043)T(0.909)PPT(0.001)SAK 147.49 7.3662e-05 121835600.0 743548.0 611543.0 708407.0 663361.0 760515.0 629346.0 600711.0 574375.0 663977.0 559261.0 True False 732944.8691699948 610127.0097565899 650164.5109900985 712146.7808474241 715783.0029300178 602430.338657181 631812.8762785023 601062.5593590279 589192.9182722206 655928.5186815601 1.1174157675644907 0.9301730179120237 0.9912124453697372 1.0857079095735382 1.0912515351044156 0.9184390089762947 0.9632343438100068 0.9163537523375036 0.8982578154347056 1.0 19.32317907683717 -6.775136102689063 24.999298778806768 0.935527659633602 1.0363541917476728 0.4523579492613353 0.05683816016119758 236.279966143077 431256.01566040044 0.02058620201808138 0.018251661861472115 1.6782779834811778e-07 6.775136102689063 0.10082653211407089 SATDGNTSTT(ph)PPTSAKK ddPTM_PC-9_AZD4547_30min_R2 1 SATDGNTSTTPPTSAKK 17 1 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 SATDGNT(0.001)S(0.032)T(0.22)T(0.745)PPT(0.001)S(0.001)AKK 58.848 0.034661000000000004 7065500.0 16551.0 12127.0 21351.0 30239.0 26041.0 19753.0 13712.0 22167.0 15741.0 19917.0 True False 21813.873717813683 16046.815593589728 21067.871789504417 23267.865737892826 22425.656650379715 18517.84178738695 14932.341436336235 18741.599496985174 16573.03712411159 19219.711892262996 1.1349740225083698 0.8349144713271932 1.0961596046601203 1.2106251055334205 1.166805037249663 0.963481757228703 0.7769284742685104 0.9751238521181845 0.8622937334863567 1.0 14.23029908950509 -6.964324661719054 7.454757984779635 0.8970412223612252 1.0807516844727538 0.3912986269172197 0.1096541091742993 0.22710823160809152 38.014909449867964 0.04095465360990984 0.03585467269044519 1.0856137574342688e-07 6.964324661719054 0.18371046211152864 SATDGNTSTT(ph)PPTSAKK ddPTM_PC-9_Lapatinib_30min_R1 2 SATDGNTSTTPPTSAKK 17 1 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 SATDGNTS(0.001)T(0.051)T(0.947)PPTSAKK;SATDGNTS(0.005)T(0.253)T(0.741)PPTSAKK 79.293 0.0055037 15178400.0 111224.0 60913.0 69610.0 61124.0 59139.0 64748.0 44984.0 40650.0 65437.0 43551.0 True False 109637.92536401631 60771.95969098353 63886.93450237061 65619.26286368663 55660.56029174753 61978.87897495995 47313.05141159756 42538.74740012091 58066.795977841655 51078.732321940195 2.1464496157224087 1.1897703198260412 1.2507541122928147 1.2846689782765173 1.0897012858684294 1.2133989266671314 0.9262769309424476 0.832807422314374 1.136809653220384 1.0 15.640435100057104 -2.4215118662239266 1.0824461808285437 1.0658768991332763 199.99999999411787 0.836853551477778 0.13823126409490885 121.88449055660446 1.0109695198337953 0.045372267448256634 59198.65073311502 0.0037886818179534956 2.4215118662239266 198.93412309498459 up SATLSGS(ph)ATNLASLTAALAK ddPTM_PC-9_AZD4547_30min_R2 2 SATLSGSATNLASLTAALAK 20 0 Q9NQT8;H0YBA8;Q9NQT8-2 Q9NQT8 KIF13B Kinesin-like protein KIF13B 1 SATLS(0.003)GS(0.972)AT(0.001)NLAS(0.024)LTAALAK;SATLS(0.006)GS(0.673)AT(0.308)NLAS(0.014)LTAALAK 183.18 2.0313e-11 45849000.0 126188.0 151583.0 216694.0 292950.0 208827.0 216863.0 220598.0 273910.0 204550.0 215820.0 True False 166313.15912654635 200579.24038287412 213820.4959746557 225414.90353238204 179834.97566640517 203302.52232765092 240230.79464504862 231583.5033256287 215362.09540289844 208264.20749049526 0.798568131944307 0.9630999142856947 1.026679036936359 1.082350665284958 0.8634943941320904 0.9761760063208615 1.1534905471263575 1.111969772031988 1.0340811702497037 1.0 17.668055392005662 -7.125672299557627 6.674026312339082 1.0836050917155602 0.956000177469535 0.34319913921339074 0.08339168006334016 0.2974720360389654 14.901058849045178 0.03306882063711144 0.025587278387109388 7.487342509497496e-08 7.125672299557627 -0.12760491424602516 SATLSGSATNLAS(ph)LTAALAK ddPTM_PC-9_Lapatinib_30min_R1 1 SATLSGSATNLASLTAALAK 20 0 Q9NQT8;H0YBA8;Q9NQT8-2 Q9NQT8 KIF13B Kinesin-like protein KIF13B 1 SATLS(0.071)GS(0.071)AT(0.003)NLAS(0.82)LT(0.035)AALAK 117.2 1.6666e-05 37284000.0 21339.0 15680.0 16474.0 15531.0 16249.0 20226.0 17035.0 14403.0 18179.0 13597.0 True False 21034.701946906673 15643.693923376333 15119.571311478992 16673.201549897196 15293.265766763143 19360.98112910884 17916.98894710484 15072.215960736572 16131.489586643384 15947.223333136339 1.3190197131809893 0.9809666295241938 0.9481005561678196 1.0455238007015533 0.9589923867803147 1.2140659677650052 1.1235177794165316 0.9451310517122056 1.0115547546841062 1.0 13.961017629104585 -4.755670925375368 24.993803676287865 1.0287153164342135 1.3190201814111324 0.5425500725189605 0.08085187996819336 158.3209345068703 685909.7767802626 0.02146315558636008 0.18597804407610632 1.755209959870077e-05 4.755670925375368 0.2903048649769189 SATRPSPS(ph)PER ddPTM_PC-9_AZD4547_30min_R2 1 SATRPSPSPER 11 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SAT(0.003)RPS(0.197)PS(0.8)PER 99.844 0.021206 44392000.0 21768.0 16182.0 23907.0 32714.0 25360.0 20005.0 16358.0 21575.0 19303.0 20193.0 True False 28689.771197472564 21412.51504374281 23589.9775594437 25172.292726261636 21839.20174546406 18754.084187550026 17813.830310355013 18241.079494178503 20323.317172144463 19486.049216270858 1.472323654685045 1.0988638490075942 1.210608538325258 1.2918110001099024 1.1207608840086638 0.9624364579706778 0.9141837892660385 0.9361096901544924 1.0429675583070213 1.0 14.250153994318287 -6.565057805928162 2.944084316322551 0.9629297608356401 1.2513837459267023 0.6905720180845383 0.09331233382824392 0.15312172389358614 2.7099792030499956 0.031945674036918774 0.033152808599380676 2.722338932296473e-07 6.565057805928162 0.28845398509106224 SATT(ph)TGSPGTEK ddPTM_PC-9_AZD4547_30min_R2 1 SATTTGSPGTEK 12 0 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 SAT(0.159)T(0.62)T(0.186)GS(0.034)PGTEK 202.61 2.0466e-06 28542000.0 110900.0 98050.0 120010.0 164040.0 142340.0 133170.0 117010.0 126500.0 110290.0 118660.0 True False 146163.89313670134 129742.74502774574 118418.58898685912 126223.1123927357 122578.54796724574 124842.8588480897 127423.6633215945 106952.33168081507 116119.70423850248 114505.74951729289 1.2764764542642235 1.1330675147290463 1.0341715545818535 1.1023299085402976 1.0705012497973623 1.0902758977114566 1.1128145430142853 0.9340345976658833 1.0140949666546295 1.0 16.805060514609117 -1.5228787452803438 0.6980585525181372 1.0378503463294042 29.935707409272112 0.6666516369669545 0.05074104181884782 187.14206590647711 1.0014317613943946 0.021553468253648823 8437.703959100349 0.029999999999999565 1.5228787452803438 28.89785706294271 SATT(ph)TGSPGTEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SATTTGSPGTEK 12 0 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 SAT(0.09)T(0.658)T(0.192)GS(0.059)PGTEK 199.4 1.672e-05 25158000.0 60353.0 53745.0 58417.0 66506.0 68118.0 57390.0 67962.0 57421.0 51966.0 44925.0 True False 70569.57087391456 59080.44841166904 59809.88282770623 62779.884435361215 54770.76688915445 54380.36737067906 61524.14735772953 55913.75959257856 52725.90443998676 53069.54687389569 1.3297564239921358 1.1132646101549821 1.1270094875659478 1.182973817065733 1.0320564262457566 1.0247000506693256 1.1593117141912619 1.0535940645101287 0.9935246774440059 1.0 15.695596610123465 -1.5228787452803376 0.4595428558198799 1.0464148935506148 6.9424798302200506 0.6423890408061308 0.05915323851561153 64.0001698075942 0.7542537816994227 0.03690577994096123 356.1847315253784 0.029999999999999995 1.5228787452803376 5.896064936669436 SATT(ph)TPSGSPR ddPTM_PC-9_AZD4547_30min_R2 1 SATTTPSGSPR 11 0 A0A096LNZ0;A0A096LP60;A0A096LP25;Q2M2I8;Q2M2I8-2 A0A096LNZ0;A0A096LP25;Q2M2I8 AAK1 AP2-associated protein kinase 1 1 SATT(0.496)T(0.496)PS(0.007)GSPR 103.08 0.0074621999999999996 3586300.0 9171.4 10644.0 13443.0 21699.0 18550.0 13529.0 10847.0 13614.0 12543.0 11710.0 True False 12087.714423029209 14084.464845235347 13264.737036499844 16696.630796208094 15974.652696307505 12683.0294912954 11812.361986576661 11510.269118597747 13205.997372957981 11300.036464246601 1.0697057891162411 1.2464087960953665 1.1738667462241887 1.4775731785500301 1.4136815174757553 1.1223883685176237 1.0453383954955422 1.0186045996414546 1.1686685626848954 1.0 13.464039807650343 -6.943802094990788 7.462346401830395 1.0629690199200104 1.2798019983901716 0.4528903996048167 0.11444385513060311 0.2275505502208224 25.447317504952306 0.043407446982661295 0.038192557855021195 1.138145812890937e-07 6.943802094990788 0.21683297847016125 SATT(ph)TPSGSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SATTTPSGSPR 11 0 A0A096LNZ0;A0A096LP60;A0A096LP25;Q2M2I8;Q2M2I8-2 A0A096LNZ0;A0A096LP25;Q2M2I8 AAK1 AP2-associated protein kinase 1 1 S(0.001)ATT(0.486)T(0.486)PS(0.025)GS(0.002)PR 97.779 0.012835 3883100.0 13487.0 15274.0 14484.0 15936.0 19167.0 17696.0 16313.0 15521.0 16652.0 12640.0 True False 15770.08271960772 16790.301777650628 14829.353490875894 15043.157585209092 15411.36394146076 16767.99060797241 14767.714544107595 15113.590195858853 16895.50399751105 14931.53194181506 1.056159728356093 1.1244862109982279 0.9931568675379504 1.0074758332787963 1.0321354835870493 1.1229919792097443 0.9890287615265584 1.012192871753095 1.131531852414686 1.0 13.866074569903263 -7.836815622420684 0.004223881446404112 2.666657496624709e-08 2.083230833524165 0.03456863130732679 0.054238720652849674 25567.797978609782 108.29436543652047 26674.283826260245 26729.134104534547 1.4560771197362846e-08 7.836815622420684 2.08323080685759 SATT(ph)TPSGSPR ddPTM_PC-9_Lapatinib_30min_R1 1 SATTTPSGSPR 11 0 A0A096LNZ0;A0A096LP60;A0A096LP25;Q2M2I8;Q2M2I8-2 A0A096LNZ0;A0A096LP25;Q2M2I8 AAK1 AP2-associated protein kinase 1 1 S(0.209)AT(0.062)T(0.361)T(0.361)PS(0.008)GSPR 83.081 0.032347 3180200.0 11250.0 12592.0 11110.0 9542.5 14394.0 12825.0 11450.0 11553.0 15318.0 10028.0 True False 11089.572937002664 12562.843997650178 10196.5786858402 10244.287282846828 13547.37321969282 12276.5046465352 12042.824974719726 12089.794556300043 13592.725534309002 11761.326438529915 0.9428845458003275 1.0681485683871934 0.8669582244088025 0.8710146203651579 1.1518575979076513 1.043802730134041 1.023934250754883 1.0279278123506608 1.155713652312162 1.0 13.521763155571932 -6.256911358609209 24.990393518002595 1.0652686459050498 0.9415803353871738 0.44676163388526846 0.07076072862937827 404.1416600862887 2230479.3070843373 0.021757782412896328 0.027166144914625923 5.534630619040412e-07 6.256911358609209 -0.12368831051787599 SATTT(ph)GSPGTEK ddPTM_PC-9_Lapatinib_30min_R1 1 SATTTGSPGTEK 12 0 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 SAT(0.007)T(0.014)T(0.763)GS(0.216)PGTEK 213.99 2.5907e-10 28243000.0 122720.0 129710.0 115410.0 99890.0 105470.0 94197.0 87606.0 95929.0 97875.0 72876.0 True False 120969.99029590833 129409.66446435874 105921.43529548327 107236.24382327178 99266.46196199828 90168.41389393178 92141.81002054979 100386.21154603202 86851.2868305584 85472.5194988337 1.415308581111371 1.514049956911877 1.2392455015547845 1.2546283232558162 1.1613845308883495 1.05494039982245 1.0780284769984707 1.1744852279381073 1.0161311183969897 1.0 16.38317302930922 -5.646747802806456 0.8055090073490322 1.0679792071643153 1.522528282553355 0.8441703532934317 0.0637175519441792 0.35458703654360024 0.38020368661870374 0.027979222809115918 0.11694083745363257 2.2555486414171087e-06 5.646747802806456 0.45454907538903977 SATTTGS(ph)PGTEK ddPTM_PC-9_AZD4547_30min_R2 1 SATTTGSPGTEK 12 0 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 SAT(0.002)T(0.072)T(0.364)GS(0.554)PGT(0.008)EK 162.67 0.00069232 26599000.0 36663.0 34050.0 32653.0 44145.0 42705.0 33659.0 32691.0 38399.0 28000.0 34179.0 True False 48321.071362226074 45055.99661595862 32219.999884908822 33968.052283451114 36776.147891957524 31554.297409085077 35600.435669141465 32465.31687123804 29480.022836867058 32982.40361327793 1.46505609260003 1.3660616474240266 0.9768845309969411 1.0298840764223862 1.115023280994364 0.9567009663414 1.0793766302347225 0.9843223450873143 0.8938106264941559 1.0 15.009408919458805 -5.189033876131046 4.085886110397558 1.009141557904199 1.44109140177465 0.8817050841074587 0.060502577535595 0.0689869389254923 2.2106135298717806 0.015973408533134715 0.046871286552708565 6.470921388625572e-06 5.189033876131046 0.431949843870451 SATTTGS(ph)PGTEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SATTTGSPGTEK 12 0 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 SATT(0.001)T(0.018)GS(0.978)PGT(0.004)EK 90.689 0.0068118 6015100.0 46560.0 54883.0 46093.0 59970.0 63120.0 49989.0 63410.0 63284.0 59645.0 50174.0 True False 54441.68839808229 60331.42153088902 47192.03192867591 56610.07532536323 50752.0891107113 47367.48883939494 57403.345751355555 61622.8620549405 60517.19528774603 59270.149022834514 0.9185346974091122 1.017905683139849 0.7962192217619468 0.9551195038087983 0.8562841488918556 0.7991795131330961 0.9685034827437374 1.0396947379227877 1.021040039302602 1.0 15.855018064425213 -7.505055130459081 9.523974557926373 1.019181508521026 0.8925851772293315 0.4620048326378997 0.06356943937096746 0.28703237319420816 147.33565778543309 0.02817676059440785 0.018063986085656694 3.125682559751314e-08 7.505055130459081 -0.12659633129169456 SATTTGS(ph)PGTEK ddPTM_PC-9_Lapatinib_30min_R1 3 SATTTGSPGTEK 12 0 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 SAT(0.001)T(0.001)T(0.064)GS(0.904)PGT(0.031)EK;SATT(0.01)T(0.006)GS(0.983)PGTEK;SATTTGS(0.999)PGTEK 167.73 0.00013971 9785800.0 72674.0 61378.0 63034.0 61683.0 64042.0 61823.0 57150.0 54432.0 66385.0 43100.4 True False 71637.65543322073 61235.883012053055 57851.587838276464 66219.37358845597 60275.175471416405 59178.974406451875 60108.94736290238 56961.1094337855 58908.022234959106 50550.24671232699 1.4171573848273908 1.2113864322074674 1.1444372995348606 1.3099713234892674 1.192381430192267 1.1706960550208496 1.189093056359791 1.126821591157441 1.165335998658816 1.0 15.625430512820808 -1.5228787500292336 0.0500833071474367 0.6253431947293688 2.2432176572567015 0.6374812705024966 0.06301365739647344 333.9949885458966 1.2673946925015216 9.644351368895702 41.79044840128838 0.029999999671957888 1.5228787500292336 1.6178744625273327 SATYS(ph)VGMQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SATYSVGMQK 10 0 Q8IUC4-2;A8MT19;Q8IUC4 Q8IUC4-2 RHPN2;RHPN2P1 Rhophilin-2;Putative rhophilin-2-like protein RHPN2P1 1 S(0.001)AT(0.292)Y(0.285)S(0.422)VGMQK 102.95 0.0026565 6767000.0 82617.0 99731.0 85309.0 129050.0 72647.0 95317.0 93288.0 103770.0 84753.0 58756.0 True False 96602.42633987038 109631.63458078267 87343.09009618427 121819.74688574474 58412.341850852994 90318.40872401146 84451.08529336788 101046.14745340314 85992.35228807697 69407.99768775995 1.3918054051126465 1.5795245250262582 1.2584009481026588 1.7551255034580482 0.841579411548908 1.3012680344175818 1.2167342108510466 1.4558285906470192 1.2389401099700885 1.0 16.082814289610706 -1.5228787452805497 0.03387654878023161 0.008544092340667614 3.2947034610282917 0.2224016403817486 0.2213994637136009 1708.4850835807154 4.443633217801789 129.72294987622902 351.60155439704187 0.029999999999985347 1.5228787452805497 3.286159368687624 SAVCIADPLPT(ph)PSQEK ddPTM_PC-9_AZD4547_30min_R2 1 SAVCIADPLPTPSQEK 16 0 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 SAVCIADPLPT(0.611)PS(0.389)QEK 189.52 7.5754e-08 5688600.0 43473.0 43503.0 43217.0 40498.0 37872.0 41014.0 46578.0 46948.0 44193.0 40481.0 True False 57296.509705426535 57564.49400246839 42643.91434251384 31161.811787862807 32614.126518304998 38449.38809638474 50723.3517664578 39693.2653577146 46528.951758202384 39063.77251145745 1.4667428674130591 1.473603041938273 1.0916486453018928 0.7977163951260214 0.8348944411024111 0.9842722713252411 1.2984755057023891 1.016114491913768 1.1911023633100308 1.0 15.253543661102858 -5.302243308856102 4.3997208875428795 1.0166058983635462 1.476022707209758 0.6213869772235596 0.13916718893966581 0.1353650849073114 6.017524724649103 0.040696244776864995 0.09535584462354234 4.986050710188501e-06 5.302243308856102 0.45941680884621183 SAVCIADPLPT(ph)PSQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAVCIADPLPTPSQEK 16 0 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 SAVCIADPLPT(0.71)PS(0.29)QEK 189.52 7.5754e-08 4501100.0 41967.0 46053.0 42304.0 39628.0 40584.0 29888.0 39596.0 31198.0 28292.0 24323.0 True False 49071.18421396736 50624.83748632607 43312.68779881344 37407.77163570944 32631.85653468167 28320.620665183036 35845.18022978514 30379.085557013383 28705.71697679456 28732.567359237946 1.707859363921068 1.7619322649930005 1.5074423130130683 1.3019293113632007 1.1357097375494376 0.9856627258920369 1.2475453300646446 1.0573049451930043 0.9990655070217819 1.0 14.810399288220674 -5.7562874649927736 1.337379503533442 1.0689790329024957 1.762705051110751 0.9277987414487208 0.07514295182615655 0.11152409982363615 0.3969885236899261 0.025847425456536944 0.06408500979343103 1.752719970353797e-06 5.7562874649927736 0.6937260182082552 SAVCIADPLPTPS(ph)QEK ddPTM_PC-9_AZD4547_30min_R2 1 SAVCIADPLPTPSQEK 16 0 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 SAVCIADPLPT(0.113)PS(0.887)QEK 184.22 7.707399999999999e-08 4741700.0 58233.0 60725.0 59671.0 54409.0 59062.0 68924.0 65848.0 76962.0 65378.0 61688.0 True False 76749.88267835451 80353.16870790282 58879.723551661205 41865.84566067036 50862.260784329614 64614.171384288886 71708.34443552145 65069.29131082118 68833.74760816757 59528.321896365844 1.2893002899018395 1.3498309065018061 0.9891043737830575 0.7032928919709097 0.8544212093342197 1.085435794692434 1.2046088676976325 1.0930812298741048 1.156319301726693 1.0 15.861288604909685 -5.262802641415337 24.97266349904342 1.0071296722041143 1.3195656196997665 0.44179178412639364 0.13878742418191217 116.23504287919403 2129278.2448214088 0.04172578568413305 0.09528934465299381 5.460059288904808e-06 5.262802641415337 0.3124359474956522 SAVCIADPLPTPS(ph)QEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAVCIADPLPTPSQEK 16 0 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 SAVCIADPLPT(0.257)PS(0.743)QEK 174.52 1.2729000000000001e-05 3299900.0 34028.0 41654.0 29606.0 31824.0 37806.0 25944.0 36710.0 25666.0 25688.0 23521.0 True False 39788.26831636479 45789.133838304224 30311.919321380246 30041.004454800073 30398.18569264179 24583.450968198227 33232.56304261573 24992.294695374876 26063.638403078556 27785.171107866463 1.4319965193628066 1.6479701946244458 1.0909387314443573 1.0811883913968392 1.0940434944464148 0.8847687449093385 1.196053927960408 0.899483202689334 0.9380413135443851 1.0 14.762027504333453 -5.34076746449715 4.962622187983903 1.0205111047541113 1.5387461529838498 0.8021945903400796 0.10296375029419728 0.08046014335249115 3.5050948583890578 0.02672902939927482 0.05848350576379075 4.562811584479909e-06 5.34076746449715 0.5182350482297384 SAVCIADPLPTPS(ph)QEK ddPTM_PC-9_Lapatinib_30min_R1 2 SAVCIADPLPTPSQEK 16 0 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 SAVCIADPLPT(0.011)PS(0.989)QEK;SAVCIADPLPT(0.25)PS(0.75)QEK 180.02 4.6674e-06 11754600.0 47682.0 67787.0 58269.0 55207.0 73261.0 69093.0 62300.0 61908.0 62200.0 55045.0 True False 47002.045936192095 67630.04336632094 53478.34774484453 59267.10694515324 68951.93201666781 66138.05345364964 65525.58916375881 64784.471686265344 55194.38100496276 64559.45490714794 0.7280427941002966 1.0475621806842894 0.8283581052807723 0.918023657888587 1.068037704404991 1.0244518568004037 1.0149650311948948 1.003485419439198 0.8549387705386544 1.0 15.978340777154077 -4.750509764773231 24.97047036932379 0.9730246843976992 0.7280422631819962 0.48047958485572373 0.0765117113247487 433.2934550023379 989863.8725359394 0.019628398769772085 0.28607736209181456 1.776193331515569e-05 4.750509764773231 -0.24498242121570302 SAVEDEGLK ddPTM_PC-9_Lapatinib_30min_R1 3 SAVEDEGLK 9 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 ;; 133.57 0.0053641999999999995 27654500.0 210813.0 175074.0 280809.0 172656.0 244361.0 211291.0 200862.0 206271.0 239826.0 191985.0 False True 207806.7679616301 174668.6269095149 257721.96797408632 185353.69820353214 229988.16641221067 202254.5764733775 211261.65153468575 215855.10368930685 212814.27040026055 225169.35144606786 0.9228910001608438 0.7757211440534402 1.144569482120729 0.8231746328404188 1.0214008475629375 0.8982331528446097 0.9382344896316263 0.958634478018684 0.9451298279874178 1.0 17.780650945168183 SAVENCQDSWR ddPTM_PC-9_AZD4547_30min_R2 2 SAVENCQDSWR 11 0 P52209-2;P52209 P52209-2 PGD 6-phosphogluconate dehydrogenase, decarboxylating 0 ; 149.94 0.0014879000000000001 13906500.0 31875.0 35695.0 34167.0 41926.0 41946.0 41945.0 34383.0 41030.0 30397.0 35776.0 False True 42010.58695881286 47232.710696230366 33713.92325567877 32260.608450242868 36122.52194066387 39322.17251920949 37443.02039130312 34689.75627560344 32003.72336329456 34523.49312936691 1.2168695329116963 1.3681324343176777 0.9765501749589908 0.9344537741113124 1.0463171210776692 1.1389975044489533 1.0845663922534177 1.0048159421647602 0.9270128965041217 1.0 15.075290825104956 -5.265614321289401 24.99438992588593 1.0195461432450315 1.2925009916741257 0.7168051327484057 0.06993139028058504 179.259912177982 1073193.3542972992 0.01963044745662227 0.043314189369367394 5.4248243244229115e-06 5.265614321289401 0.27295484842909423 SAVENCQDSWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAVENCQDSWR 11 0 P52209-2;P52209 P52209-2 PGD 6-phosphogluconate dehydrogenase, decarboxylating 0 183.85 0.006077300000000001 7805900.0 15601.0 22642.0 18517.0 16991.0 21216.0 20113.0 15603.0 14292.0 19397.0 12923.0 False True 18241.941166204506 24889.748124235004 18958.515506113563 16039.049355565236 17058.87710033033 19058.238873087073 14124.970884062464 13916.850143625714 19680.644429481268 15265.837601588286 1.194951868497971 1.6304213875329991 1.2418916014238932 1.0506498086876348 1.117454380528422 1.2484240544458707 0.9252666805909737 0.9116335773267874 1.289195191453737 1.0 13.898019128642513 -5.53362919506839 4.897627904649785 1.0789146612374982 1.4204220175685698 0.4418620734110693 0.15125089692912258 0.14913328100891432 9.919472371301042 0.04015418696292313 0.07630255829823268 2.9266501142601593e-06 5.53362919506839 0.34150735633107154 SAVENCQDSWR ddPTM_PC-9_Lapatinib_30min_R1 2 SAVENCQDSWR 11 0 P52209-2;P52209 P52209-2 PGD 6-phosphogluconate dehydrogenase, decarboxylating 0 ; 166.29 0.004993600000000001 26650000.0 44619.0 56106.0 52037.0 48225.0 56001.0 49004.0 56193.0 52358.0 46089.0 49414.0 False True 43982.72487787754 55976.09000414235 47758.718728628875 51771.62737388403 52707.13128220215 46908.213153903365 59102.39858553935 54790.743822276294 40897.97148131396 57955.14405998377 0.7589097670494144 0.965851969002215 0.8240634977837072 0.8933051278468089 0.9094469893414481 0.8093882590534708 1.0197955598966015 0.9453991480992211 0.7056831993892452 1.0 15.82264909911534 SAVGHEYQSK ddPTM_PC-9_AZD4547_30min_R2 2 SAVGHEYQSK 10 0 Q14247-3;Q14247;Q14247-2 Q14247-3 CTTN Src substrate cortactin 0 ; 112.83 0.0011700999999999999 6411000.0 26614.1 20911.7 68791.0 107654.0 89265.0 74015.0 45319.0 81121.0 54986.0 65031.0 False True 35076.83019233069 27670.998074418276 67878.78639275901 82836.03353772002 76872.0955760586 69386.8303494883 49352.30320546395 68585.61342513349 57892.44770385616 62754.28448389587 0.5589551451476142 0.4409419739542925 1.0816597934469032 1.3200060237955158 1.2249696767044753 1.1056907256634323 0.786437190884215 1.0929232002116773 0.9225258192325121 1.0 15.93742634048787 -5.264719056977761 24.66613020153706 1.076166593451502 0.49994852211685076 0.7165286646543048 0.14251182411892868 118.36582983789606 890226.9208763513 0.040587845501288626 0.09052806192874305 5.436018712248431e-06 5.264719056977761 -0.5762180713346512 SAVGHEYQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SAVGHEYQSK 10 0 Q14247-3;Q14247;Q14247-2 Q14247-3 CTTN Src substrate cortactin 0 ; 124.67 0.00033996 4117200.0 31377.0 33736.0 59201.0 65377.0 73917.0 68484.0 56391.0 54603.0 55628.0 45608.0 False True 36688.50637600145 37085.08712654321 60612.57636104273 61714.138645093786 59433.494467624245 64892.578480808224 51049.23624451494 53169.72910666071 56441.45426216337 53876.36936727065 0.6809758490944149 0.6883367896180477 1.1250308265549953 1.1454769385886738 1.103145872032897 1.2044720021581448 0.9475255449474819 0.9868840408344364 1.047610574450679 1.0 15.71736501297186 -5.256483802093723 24.87003047478702 1.0738550676915766 0.6846562604788232 0.810957547339814 0.07440493109932829 159.25899504552376 799249.0379942812 0.02077623777396543 0.05147713538243676 5.540082064292143e-06 5.256483802093723 -0.38919880721275335 SAVGHEYQSK ddPTM_PC-9_Lapatinib_30min_R1 2 SAVGHEYQSK 10 0 Q14247-3;Q14247;Q14247-2 Q14247-3 CTTN Src substrate cortactin 0 ; 130.01 0.00019088 7008400.0 57956.0 46235.0 87600.0 63374.0 83677.0 82410.0 67387.0 75264.0 97263.0 54522.0 False True 57129.53681217124 46127.945698169926 80397.86614577881 68034.73536946649 78755.28337531158 78885.5164070929 70875.96913287677 78761.04020474064 86308.2167152041 63946.0550540016 0.8934020521504586 0.7213571761262753 1.257276403960868 1.063939523900451 1.231589396856519 1.233626004613969 1.1083712525037384 1.2316794231986317 1.3497035374945014 1.0 15.964567738975678 -5.263074071481291 24.99998121693177 1.1892057995420195 0.8073795959276776 0.6764050197243598 0.10430297973714746 71.4511305365998 1092749.304240094 0.025813611017835865 0.05870631379331679 5.456647868117013e-06 5.263074071481291 -0.38182620361434194 SAVPPGADK ddPTM_PC-9_Lapatinib_30min_R1 1 SAVPPGADK 9 0 P46783;F6U211;A0A2R8Y7H1;S4R435;A0A2R8YFH6;A0A1W2PQS6 P46783 RPS10;RPS10-NUDT3 40S ribosomal protein S10 0 89.355 0.043356 2529600.0 30682.0 29836.0 28721.0 29320.0 29771.0 25845.0 32644.0 29058.0 24384.0 26467.0 False True 30244.46905361029 29766.91657511838 26359.670246266112 31476.29060865277 28019.928312038002 24739.66959763759 34334.14659168128 30408.140761444378 21637.617145096654 31041.785684939303 0.974314730491943 0.9589305485592777 0.8491673292833526 1.0139974203843651 0.9026519478108687 0.7969795890202495 1.1060622265792959 0.9795873558974297 0.6970480810836435 1.0 14.921923930782832 -5.021588349189887 23.690891049629514 0.9214619422378091 0.970468779098408 0.029600214373207367 0.11119326668600611 1569.9682401804052 1722893.0609048547 0.027905228565742027 0.07563423881827898 9.515062620504356e-06 5.021588349189887 0.049006836860598924 SAVQKPPS(ph)TGSAPAIESVD ddPTM_PC-9_Lapatinib_30min_R1 2 SAVQKPPSTGSAPAIESVD 19 1 Q9NUQ3;Q9NUQ3-2 Q9NUQ3 TXLNG Gamma-taxilin 1 SAVQKPPS(0.673)T(0.222)GS(0.1)APAIES(0.004)VD;SAVQKPPS(0.633)T(0.215)GS(0.097)APAIES(0.054)VD 108.97 0.00083696 3353300.0 48642.0 37804.0 79614.0 41062.0 41569.0 44235.0 40283.0 36776.0 59838.0 35745.0 True False 47948.35616014967 37716.46716067084 73068.44423892732 44081.83645881648 39123.99314779845 42343.17216682139 42368.65663376721 38484.74721738862 53098.41431792545 41923.475622781414 1.1437113800291479 0.8996502937885126 1.7429004430925947 1.051483346835447 0.9332239888655197 1.0100110150173691 1.0106188956037767 0.9179760658125355 1.2665556356942773 1.0 15.355470706536783 -5.970010051260835 24.99940943329013 1.0153845551204523 1.2544016266261184 0.20281031455282528 0.21362253806963488 323.53231536566625 269692.25013404223 0.05956361101521342 0.08834580065284951 1.0714945064067552e-06 5.970010051260835 0.2390170715056661 SAVRPAS(ph)LNLNR ddPTM_PC-9_AZD4547_30min_R2 2 SAVRPASLNLNR 12 1 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 SAVRPAS(1)LNLNR;SAVRPAS(1)LNLNR 72.815 0.011387999999999999 65427000.0 42305.0 43404.0 56519.0 85392.0 67416.0 67964.0 52550.0 54194.0 40005.0 78217.0 True False 55757.11000133579 57433.4941885189 55769.52113114143 65706.19369324858 58056.45208486618 63714.200336048445 57226.8481971608 45819.56255422991 42119.58262817383 75478.64663740205 0.7387136956653695 0.7609237413122718 0.7388781279963474 0.8705269188105592 0.7691771735623221 0.8441354366372018 0.7581859339910725 0.6070533136920988 0.5580330928628793 1.0 16.203780934615352 -7.539186850372421 23.642596205193833 0.6860497453001443 0.7878705307763593 0.03365491659751241 0.1170826635718412 258.25599604382046 374396.6581608619 0.05217331601166393 0.030136528977286886 2.8894364669862127e-08 7.539186850372421 0.10182078547621498 SAVRPAS(ph)LNLNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAVRPASLNLNR 12 1 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 S(0.007)AVRPAS(0.993)LNLNR 52.008 0.046402 20909000.0 28744.0 22687.0 21101.0 28361.0 31759.0 27803.0 34269.0 28454.0 23173.0 22703.0 True False 33609.791480121945 24939.21542684036 21604.127865988128 26772.025117602578 25536.051933889103 26344.961735615772 31022.792233925302 27707.11264950505 23511.861285991097 26818.87418315087 1.2532141077434753 0.929912838865868 0.8055568521799121 0.99825313079034 0.9521671849272588 0.9823291446054496 1.1567522194281954 1.0331199013160746 0.876690838154667 1.0 14.710961055849417 -7.029749649297284 24.865047077554344 1.026563567984299 0.9742765282123164 0.005562736615419395 0.12225541647869449 2742.593715653879 2292278.5049682083 0.047704528916067745 0.03701276342706285 9.337924338709314e-08 7.029749649297284 -0.05228703977198268 SAVRPAS(ph)LNLNR ddPTM_PC-9_Lapatinib_30min_R1 2 SAVRPASLNLNR 12 1 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 S(0.001)AVRPAS(0.999)LNLNR;SAVRPAS(1)LNLNR 71.031 0.013384 57253000.0 43646.0 39864.0 41879.0 37758.0 50390.0 43681.0 52251.0 52599.0 52685.0 29969.0 True False 43023.60003630388 39771.69735723687 38435.87027761494 40534.84927699559 47426.159270551696 41812.86545538432 54956.301113893474 55042.94156209005 46751.06050235473 35149.1017188176 1.2240312819508143 1.1315139054021544 1.093509318818174 1.1532257524320928 1.3492851012224132 1.1895856056258525 1.5635193625580421 1.5659843031670417 1.3300783865360022 1.0 15.10120019936314 -6.548442202247902 1.5112385016751668 1.3935719237476074 1.1437614112918293 0.19355018210306052 0.1626675120975527 0.49377687719781516 2.3131311822636134 0.06555069378576327 0.07087215384281197 2.8285105161792607e-07 6.548442202247902 -0.24981051245577812 SAVS(ph)PDLHITPIYEGR ddPTM_PC-9_AZD4547_30min_R2 3 SAVSPDLHITPIYEGR 16 0 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 S(0.08)AVS(0.92)PDLHITPIYEGR;S(0.03)AVS(0.97)PDLHITPIYEGR;S(0.053)AVS(0.947)PDLHITPIYEGR 77.795 0.0058456 7820200.0 18703.8 18286.699999999997 34591.0 60909.0 50764.0 39628.0 29839.9 57853.0 34466.0 45976.0 True False 24651.219336791954 24197.518159091047 34132.30073864211 46867.37108466927 43716.294850423415 37150.05489548776 32495.59329245402 48913.148179685275 36287.80239626644 44366.394234005274 0.5556281902642803 0.5454019551704858 0.7693278060555325 1.0563709738833607 0.9853470313554672 0.8373467246300028 0.7324371036568776 1.1024819353517594 0.8179119133475381 1.0 15.437179686097174 -5.438637894290957 3.4529060619560745 0.9272159293331272 0.5521424442894517 0.6645473964688373 0.10791356765859067 0.14387684198897852 3.2283900540395343 0.029790402372198516 0.06704214094598937 3.642185874475149e-06 5.438637894290957 -0.37507348504367555 SAVS(ph)PDLHITPIYEGR ddPTM_PC-9_Lapatinib_30min_R1 2 SAVSPDLHITPIYEGR 16 0 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 S(0.021)AVS(0.979)PDLHITPIYEGR;S(0.143)AVS(0.857)PDLHITPIYEGR 68.525 0.013082 4310100.0 21127.8 17381.8 21612.1 15149.099999999999 25005.0 26830.0 22677.0 21787.0 30552.0 21795.5 True False 20826.513697636005 17341.553510034602 19835.23656311856 16263.215349916156 23534.25506172148 25682.543443784747 23851.10410058684 22799.303557353873 27110.9120331772 25562.82313432178 0.814718843384454 0.6783896058315665 0.7759407659667641 0.6362057611735552 0.9206438169234659 1.0046833758866884 0.9330387326649883 0.891893021265813 1.0605601693803877 1.0 14.641759554526558 -6.394478236270209 5.285676243422983 0.9677602390248322 0.7274534703248509 0.7848408528609525 0.0625121700823638 0.10206157216110474 3.967340425702689 0.0187991233516326 0.021313408100484068 4.032011514919005e-07 6.394478236270209 -0.24030676869998135 SAYLPGQTS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 SAYLPGQTSPK 11 0 H0YJ41;Q9P203-5;Q9P203 H0YJ41 BTBD7 BTB/POZ domain-containing protein 7 1 SAYLPGQT(0.078)S(0.922)PK;SAYLPGQT(0.371)S(0.629)PK;SAYLPGQT(0.295)S(0.705)PK;SAYLPGQT(0.003)S(0.997)PK 150.51 0.00033797 29893400.0 296580.0 274737.0 273183.0 325740.0 307130.0 292246.0 317242.0 277513.0 279630.0 305974.0 True False 390886.27075277566 363540.36247514316 269560.4149253985 250645.67563283182 264490.30094969895 273971.81142088206 345475.923420812 234629.74246433246 294410.6709240408 295261.94339123706 1.3238626904071802 1.231246933823211 0.9129534671124794 0.84889258925155 0.8957818874721551 0.9278940871084612 1.1700658725362343 0.7946494552243604 0.9971168906584473 1.0 18.1716358924769 -5.180430609969369 4.02878273016278 0.938198947767991 1.301375989511291 0.6585372155200928 0.09688258073349104 0.13187201205820984 3.9758959156321096 0.025266407550016988 0.0751148603513763 6.600386844770666e-06 5.180430609969369 0.3631770417433001 SAYLPGQTS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 SAYLPGQTSPK 11 0 H0YJ41;Q9P203-5;Q9P203 H0YJ41 BTBD7 BTB/POZ domain-containing protein 7 1 SAYLPGQT(0.25)S(0.75)PK;SAYLPGQT(0.045)S(0.955)PK;SAYLPGQT(0.066)S(0.934)PK 140.45 0.00012132 30921200.0 259408.0 231230.0 195265.0 215177.0 198651.0 185235.0 194358.0 187858.0 189983.0 172686.0 True False 255708.79435039873 230694.60114172855 179211.06544469768 231001.83438942922 186966.73874289278 177312.9308538749 204420.9062390023 196586.56848934633 168585.113930319 202534.5450103689 1.2625440975380646 1.1390382866780477 0.8848419682455793 1.140555229122039 0.9231350569519925 0.8754700628714831 1.0093137752304766 0.9706322863553077 0.8323770837300283 1.0 17.627808474605132 -1.5228860961328041 0.6407859593669495 0.9406428072704064 29.109544856814132 0.579950940460481 0.08489946237261695 145.63503736245505 0.9731581816806503 0.035353508669938465 5806.972345594646 0.02999949222539799 1.5228860961328041 28.168902049543725 SAYPPPAPAYALS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 3 SAYPPPAPAYALSSPR 16 0 O14497-2;O14497 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 SAYPPPAPAY(0.001)ALS(0.499)S(0.499)PR;SAYPPPAPAYALS(0.5)S(0.5)PR;SAYPPPAPAYALS(0.5)S(0.5)PR 194.67 9.171e-12 23619200.0 80023.6 89739.4 97866.0 138214.0 115247.0 104686.0 98515.0 129317.0 96743.0 100056.0 True False 105469.44020571791 118745.9061003865 96568.23289549166 106350.89768501336 99246.94335802451 98139.96787092529 107282.64415115687 109334.0290590352 101856.6374752511 96553.06989467614 1.092346833930481 1.2298511712773004 1.0001570431766909 1.1014760877207226 1.0279004434171481 1.0164354999585223 1.11112618447228 1.1323723748846206 1.054929041472843 1.0 16.55903450979131 -5.26402382901732 24.99119240266654 1.0615178800471472 1.1610990005839639 0.3745693813911334 0.05411774049719122 223.1728980132625 2158070.31010431 0.013846465983515986 0.03114819386642267 5.444727777053081e-06 5.26402382901732 0.09958112053681667 SAYPPPAPAYALS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAYPPPAPAYALSSPR 16 0 O14497-2;O14497 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 SAYPPPAPAYALS(0.5)S(0.5)PR 108.66 0.00077062 4902600.0 19412.0 17055.0 22739.0 19690.0 25836.0 27076.0 25644.0 21220.0 21612.0 16999.0 True False 22698.068195523476 18748.107687431664 23281.183998137727 18586.8331358413 20773.621265277823 25656.086895426128 23214.81467351777 20662.99748444849 21928.034614112963 20080.784135990038 1.1303377418834246 0.9336342425906632 1.1593762395170482 0.9256029550424187 1.0345024937570062 1.277643677740835 1.1560711233338108 1.0289935564525576 1.091990953421593 1.0 14.293527985840944 -6.579497630447947 24.99999354241455 1.1200727585648385 1.03124477906018 0.12049339733548203 0.09826039491674025 157.48203115246199 69534.64774051751 0.03197422660916704 0.03197423252199336 2.63331231123907e-07 6.579497630447947 -0.08882797950465848 SAYPPPAPAYALS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 3 SAYPPPAPAYALSSPR 16 0 O14497-2;O14497 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 SAYPPPAPAY(0.235)ALS(0.382)S(0.382)PR;SAYPPPAPAYALS(0.5)S(0.5)PR;SAYPPPAPAYALS(0.5)S(0.5)PR 142.57 2.6725e-05 20443300.0 94147.0 95408.0 99722.0 73973.0 92641.0 85386.0 93899.0 88933.0 98590.0 76079.0 True False 92804.44651555488 95187.08863785019 91523.24209805201 79413.22118669421 87192.03851921366 81734.23982448762 98760.63076866438 93065.15184587848 87485.75600127457 89229.1537811045 1.0400686612272625 1.0667711684385308 1.0257100759083218 0.8899918672490095 0.9771698466749079 0.9160037539411919 1.1068202104767502 1.0429904117905724 0.9804615677056985 1.0 16.44522753749272 -10.248438438013343 15.185651820029223 0.9999999999524593 1.0048064713156744 0.0005691544376567048 0.0630948460439198 0.0 0.0 0.06522622651868945 0.015819683617471787 5.643669356550651e-11 10.248438438013343 0.0048064713632151035 SAYPPPAPAYALSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SAYPPPAPAYALSSPR 16 0 O14497-2;O14497 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 SAYPPPAPAYALS(0.441)S(0.559)PR 133.87 3.5042000000000003e-06 4143200.0 34244.0 24186.0 38112.0 37217.0 38689.0 39959.0 38893.0 39633.0 33988.0 30784.0 True False 40040.832850170314 26587.026240294475 39020.734620564865 35131.85214914196 31108.16818131033 37863.479696200804 35208.77347906436 38592.675744634624 34485.01020102123 36364.89551399008 1.1010847765193235 0.7311179054554434 1.073033046542181 0.9660924815699319 0.8554450038043582 1.0412096380597107 0.9682077448983473 1.06126183505154 0.9483049439191807 1.0 15.15025881060884 -6.798828429738957 24.998881582890505 1.0054013632755934 0.9416976342051373 0.07514658132884067 0.10203279308256076 440.53380000792805 294544.4347425062 0.034022345641786245 0.030005579847241688 1.5891744361102967e-07 6.798828429738957 -0.06370372907045607 SAYPPPAPAYALSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 SAYPPPAPAYALSSPR 16 0 O14497-2;O14497 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 SAYPPPAPAYALS(0.233)S(0.767)PR 142.57 2.6725e-05 8098200.0 30276.0 28105.0 32025.0 30592.0 30046.0 23893.0 25592.0 27575.0 31378.0 29390.0 True False 29844.25868806157 28039.924599266058 29392.02812007495 32841.83773192036 28278.753352708783 22871.15208730336 26917.028537382288 28856.23516748671 27843.879215011595 34470.0223402866 0.8658032882439214 0.8134582659232741 0.8526837560451249 0.9527652000833398 0.8203868588636852 0.6635084788028366 0.7808822481070224 0.8371400193077677 0.8077708491203747 1.0 15.073054613276687 SAYQEYDS(ph)DSDVPEELKR ddPTM_PC-9_AZD4547_30min_R2 3 SAYQEYDSDSDVPEELKR 18 1 Q96JG6;H0Y7Q2;Q96JG6-3 Q96JG6 CCDC132 Coiled-coil domain-containing protein 132 1 S(0.001)AYQEY(0.001)DS(0.975)DS(0.023)DVPEELKR;SAYQEYDS(0.999)DS(0.001)DVPEELKR;SAY(0.001)QEY(0.006)DS(0.972)DS(0.021)DVPEELKR 109.56 0.00011279 12621300.0 53323.9 69505.2 62515.3 64327.3 67118.0 71021.0 73384.0 77272.0 69651.0 71281.3 True False 70279.79099397777 91971.39665173354 61686.30627522859 49497.63483187784 57799.824241011695 66580.04564278891 79915.03383635503 65331.387933912556 73332.60966466536 68785.76338333914 1.02172001206576 1.337070232675651 0.896788859221556 0.719591270013685 0.8402876031032259 0.9679335136798891 1.1617961320134385 0.9497806627488373 1.0661015602311033 1.0 16.06982238020936 -5.279099110992792 24.969180560831525 0.9445081348740865 1.1793951402638718 0.3185379065398587 0.133829922492697 853.7957846869318 1207185.2554318968 0.03758313525259159 0.07850428976881808 5.258972369007568e-06 5.279099110992792 0.23488700538978535 SAYQEYDS(ph)DSDVPEELKR ddPTM_PC-9_Lapatinib_30min_R1 2 SAYQEYDSDSDVPEELKR 18 1 Q96JG6;H0Y7Q2;Q96JG6-3 Q96JG6 CCDC132 Coiled-coil domain-containing protein 132 1 SAYQEY(0.002)DS(0.931)DS(0.067)DVPEELKR;SAYQEYDS(0.992)DS(0.008)DVPEELKR 96.54 0.00037966 15460100.0 57514.0 78641.0 68002.0 64926.0 77715.0 71516.0 71229.0 70512.0 75453.0 56003.0 True False 56693.839813224135 78458.91159618845 62411.138055311065 69700.8746267868 73143.95649356864 68457.42739193847 74916.88909382632 73788.24493671172 66954.68858468579 65683.0439306932 0.8631426989444307 1.1945078501382485 0.9501864457007421 1.0611699832354466 1.1135896285614895 1.042238959938774 1.1405818703054689 1.123398681318285 1.0193603185524471 1.0 16.0032333666219 -5.9874832479232625 24.797386200393568 1.081749438691097 1.0191145934806431 0.10144132130895955 0.08842357095473963 502.83929987425125 996182.4241192878 0.023370053753815023 0.03464069133127264 1.0292402273966102e-06 5.9874832479232625 -0.06263484521045393 SCAS(ph)SYQR ddPTM_PC-9_AZD4547_30min_R2 2 SCASSYQR 8 0 J3KNG8;Q8TF40;Q8TF40-2;Q8TF40-3;A0A087WX11 J3KNG8 FNIP1 Folliculin-interacting protein 1 1 S(0.001)CAS(0.572)S(0.413)Y(0.014)QR;S(0.014)CAS(0.493)S(0.493)Y(0.001)QR 82.749 0.016028 8981400.0 24745.2 23171.5 31183.0 48323.0 38392.0 34222.0 27666.0 48063.0 31034.0 34596.0 True False 32613.65886786557 30661.234231620718 30769.49304538977 37182.878932907646 33061.933494158366 32082.092930084356 30128.220403856343 40635.96772786569 32674.393882833283 33384.80457020283 0.9769012964950666 0.918418862304409 0.9216616194558369 1.1137665597148572 0.9903288013753226 0.9609789047175914 0.9024531007962494 1.2171995089087562 0.9787205377861156 1.0 15.026903974477827 -5.423802824585671 0.496218006890001 1.034294879231181 0.9072663252213901 0.07914829714073046 0.08846673293108175 6.379552053873635 1.9065563960956495 0.0651347346095585 0.4415991265094858 3.7687486630020693e-06 5.423802824585671 -0.12702855400979096 SCAS(ph)SYQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SCASSYQR 8 0 J3KNG8;Q8TF40;Q8TF40-2;Q8TF40-3;A0A087WX11 J3KNG8 FNIP1 Folliculin-interacting protein 1 1 S(0.012)CAS(0.494)S(0.494)YQR;S(0.189)CAS(0.442)S(0.369)YQR 92.051 0.0082649 5396100.0 19841.6 20786.5 23481.2 24948.0 36669.0 30218.0 30175.0 38996.0 34384.0 28745.0 True False 23200.390990536707 22850.04634680728 24041.08086094691 23550.2444425073 29483.97268061902 28633.314884251246 27316.605551918517 37972.39631967734 34886.80095186285 33956.240954705194 0.6832437966700762 0.6729262634602972 0.7080018336839968 0.6935468644459607 0.8682931871036076 0.843241597986235 0.8044649461745957 1.1182744394566337 1.0274046823498204 1.0 15.051389137139664 -7.074339087901528 0.7191288885899915 1.0585052440119531 0.6747701184821094 0.8037193250851247 0.06741593362171186 0.2971031861582348 0.316740510582551 0.05550194563856708 0.04148336143466968 8.426765568966384e-08 7.074339087901528 -0.3837351255298437 SCAS(ph)SYQR ddPTM_PC-9_Lapatinib_30min_R1 1 SCASSYQR 8 0 J3KNG8;Q8TF40;Q8TF40-2;Q8TF40-3;A0A087WX11 J3KNG8 FNIP1 Folliculin-interacting protein 1 1 S(0.01)CAS(0.605)S(0.385)YQR 81.95 0.017159 3451800.0 13394.0 10614.0 12200.0 11518.0 14233.0 15444.0 13816.0 11133.0 16283.0 11264.0 True False 13202.99910384122 10589.42393512221 11196.963093361876 12365.072142921641 13395.84292315464 14783.496121722383 14531.324877792813 11650.279823014671 14449.037072408502 13210.967391663433 0.9993968429725109 0.8015630968708994 0.8475505813773743 0.9359702265804107 1.0139940949069233 1.119032065059162 1.0999440424750855 0.8818642479101411 1.0937152930622123 1.0 13.68944849337529 -6.1428367490621465 2.8640951268678307 1.0374266332250641 0.8762017155538067 0.43840235178871434 0.07842818467840641 0.2509336115298668 3.971456957308546 0.0248809974927551 0.033727055365920695 7.19719469117155e-07 6.1428367490621465 -0.16122491767125746 SCDDEDWQPGLVT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 SCDDEDWQPGLVTPR 15 0 A0A590UJJ7;V9GYX6;A0A590UJ71;Q92698 A0A590UJJ7 RAD54L DNA repair and recombination protein RAD54-like 1 SCDDEDWQPGLVT(1)PR;SCDDEDWQPGLVT(1)PR 161.91 9.246299999999999e-15 2499700.0 9903.2 10281.4 15914.5 19816.4 19291.0 17255.1 12315.6 17782.1 14866.5 15255.599999999999 True False 13052.211600643619 13604.66148626482 15703.46333165043 15248.035140328027 16612.77763689855 16176.135869262424 13411.66454152148 15034.28503700727 15652.312839438724 14721.50608744324 0.8866084436684469 0.9241351669764932 1.0667022272296416 1.03576597732306 1.128469977067664 1.0988098482029576 0.9110253028364406 1.021246396102829 1.0632276851611955 1.0 13.845637653779702 -5.160502773250974 4.348477684116479 1.0417402245477043 0.8956126646290482 0.4854318012116664 0.056083288467656124 0.19827393267243903 6.287878752546397 0.01551416572811028 0.04567932894451284 6.910305167143539e-06 5.160502773250974 -0.1461275599186561 SCDDEDWQPGLVT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SCDDEDWQPGLVTPR 15 0 A0A590UJJ7;V9GYX6;A0A590UJ71;Q92698 A0A590UJJ7 RAD54L DNA repair and recombination protein RAD54-like 1 SCDDEDWQPGLVT(1)PR 161.14 0.0007251 1979900.0 4659.5 7873.8 6949.6 7581.3 8737.9 7980.9 7555.9 7482.0 8092.2 5460.6 True False 5448.261320680079 8655.458827868624 7115.30482050477 7156.544339906225 7025.771220539986 7562.367554428509 6840.150452021251 7285.60542783429 8210.533116061672 6450.563553914184 0.844617881080187 1.3418143632762933 1.1030516575853628 1.1094448229354557 1.0891716920263141 1.1723576539044693 1.0603957925305094 1.1294525458032896 1.2728396592696996 1.0 12.655209491852357 -8.009890914228071 24.593844104448518 1.1579952382253111 1.1131517877406008 0.002415654852466864 0.1302029560535764 1969.9694700193957 4898309.437143439 0.07227994882034526 0.031417988109274146 9.774827135198664e-09 8.009890914228071 -0.04484345048471039 SCDDEDWQPGLVT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 SCDDEDWQPGLVTPR 15 0 A0A590UJJ7;V9GYX6;A0A590UJ71;Q92698 A0A590UJJ7 RAD54L DNA repair and recombination protein RAD54-like 1 SCDDEDWQPGLVT(1)PR;SCDDEDWQPGLVT(1)PR 160.03 0.0001509 3601200.0 12294.3 14815.7 14271.9 11786.5 13749.7 12461.4 12413.3 8839.3 11326.099999999999 8762.7 True False 12118.981027501506 14781.395156923898 13098.519473127166 12653.31852861138 12940.969678950287 11928.454970942197 13055.999935256623 9250.006147451135 10050.435348879566 10277.321019436195 1.1791965050602597 1.4382537169919787 1.2745071841538858 1.2311884103534143 1.2591773337114478 1.1606580108165758 1.2703699641731017 0.9000405971515116 0.9779236563567929 1.0 13.327176626992996 -7.75625789512769 24.998783112170557 0.954236565801054 1.261686112606462 0.7742965851032415 0.07413240349866061 55.81041355924365 269268.7889910715 0.03690257361060721 0.02047636966843082 1.7528393120899963e-08 7.75625789512769 0.30744954680540804 SCDELSPVS(ph)PTQGGYPSEPTR ddPTM_PC-9_AZD4547_30min_R2 2 SCDELSPVSPTQGGYPSEPTR 21 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 SCDELS(0.437)PVS(0.52)PT(0.043)QGGYPSEPTR;SCDELSPVS(0.995)PT(0.005)QGGYPSEPTR 273.01 9.528299999999996e-101 29189600.0 96643.0 100161.0 121564.0 149547.0 128250.0 118139.0 110381.0 156696.0 123261.0 126053.0 True False 127373.46370072335 132536.08449489094 119951.98193149353 115071.24962811804 110444.70125614229 110751.74965423538 120204.69516366911 132482.23371586562 129776.32481768106 121639.92283754713 1.0471353543263382 1.0895771832402088 0.9861234628674675 0.9459990350519895 0.9079642495633912 0.9104884898862263 0.988201014597857 1.0891344767852134 1.0668892399002938 1.0 16.89225728074286 -10.058516543291299 9.557551210524231 1.0000023289658324 1.0003536891366167 0.0 0.06509573082320746 0.0 0.0 0.0723923718245563 0.017557729148331383 8.739437013994621e-11 10.058516543291299 0.0003513601707842984 SCDELSPVS(ph)PTQGGYPSEPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SCDELSPVSPTQGGYPSEPTR 21 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 S(0.002)CDELS(0.104)PVS(0.68)PT(0.213)QGGY(0.001)PSEPTR;SCDELS(0.029)PVS(0.966)PT(0.005)QGGYPSEPTR;SCDELS(0.008)PVS(0.918)PT(0.073)QGGYPSEPTR 235.21 4.7056000000000005e-51 25796100.0 84998.0 93249.0 94568.0 101274.0 155781.0 144482.0 174388.0 196036.0 158966.0 135365.0 True False 99386.48261297669 102506.14445882814 96822.85977113727 95599.94611473818 125256.83133326557 136905.10957397555 157868.7061802143 190890.2627173114 161290.57701587412 159905.60295124975 0.6215322088699827 0.6410416055907627 0.6055001074643742 0.5978523850967475 0.7833173386141603 0.8561620546574198 0.9872618799251429 1.1937684433453397 1.008661197850876 1.0 17.28686096490211 -6.8858479456535715 1.3041659611668257 1.0770924800448278 0.6154722339923084 0.9125169698941422 0.05946457350566822 0.11231153839622107 0.3967796369461994 0.030360287706500146 0.024464839061094066 1.3006248705968852e-07 6.8858479456535715 -0.4616202460525194 SCDELSPVS(ph)PTQGGYPSEPTR ddPTM_PC-9_Lapatinib_30min_R1 2 SCDELSPVSPTQGGYPSEPTR 21 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 SCDELS(0.013)PVS(0.932)PT(0.055)QGGYPSEPTR;SCDELSPVS(0.993)PT(0.007)QGGYPSEPTR 229.37 2.2346e-41 22124300.0 45752.0 45062.0 46848.0 39426.0 63228.0 68138.0 64286.0 66110.0 74352.0 67544.0 True False 45099.56809011075 44957.66170760104 42996.33827850963 42325.519561280504 59509.053351030845 65223.89657743592 67614.4145261863 69181.71194642066 65977.69479872979 79218.89040327723 0.5693032035733363 0.5675118835764603 0.5427536040915174 0.5342856905192089 0.7511977641707666 0.8233376691519231 0.853513779124949 0.8732981690887035 0.8328530538973611 1.0 16.273556873509726 -6.4966691583653216 2.0007929518083083 0.873369725990701 0.5502580855622939 0.9127213149629876 0.04706429660343348 0.08780951894203315 0.7045358380384098 0.01660451023948153 0.0183033645434337 3.186624138962083e-07 6.4966691583653216 -0.323111640428407 SCDEPLT(ph)PPPHSPTSMLQLIHDPVSPR ddPTM_PC-9_AZD4547_30min_R2 1 SCDEPLTPPPHSPTSMLQLIHDPVSPR 27 0 I3VM54;Q9Y2K7;Q9Y2K7-3;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 1 S(0.073)CDEPLT(0.859)PPPHS(0.025)PT(0.025)S(0.019)MLQLIHDPVSPR 43.099 0.03863 8844700.0 7861.3 8564.3 19978.0 30108.0 22063.0 18215.0 13407.0 24118.0 18374.0 21171.0 True False 10361.029874802047 11332.542490985452 19713.078666606703 23167.065763962994 18999.933285101488 17076.01317051856 14600.197027199529 20391.117276505098 19345.212128735562 20429.809733950886 0.5071525388503139 0.5547062179513441 0.964917389017427 1.1339834323304172 0.9300102904789571 0.835838091146836 0.7146516398014453 0.9981060784241428 0.9469110275945005 1.0 14.318388147636071 -5.244255835126924 7.532138406677855 0.9353504357029516 0.5286385325206349 0.7124444292088778 0.10406406898944282 0.10453558210606735 32.55310142322067 0.0295765430185516 0.07436245739238766 5.698284975948001e-06 5.244255835126924 -0.40671190318231676 SCDEPLT(ph)PPPHSPTSMLQLIHDPVSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SCDEPLTPPPHSPTSMLQLIHDPVSPR 27 0 I3VM54;Q9Y2K7;Q9Y2K7-3;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 1 S(0.005)CDEPLT(0.501)PPPHS(0.39)PT(0.052)S(0.052)MLQLIHDPVSPR 69.98100000000001 0.00021635 8675500.0 19000.0 20190.0 29692.0 32751.0 32871.0 29943.0 32631.0 26524.0 28907.0 22044.0 True False 22216.324732894398 22194.329768938467 30399.969887537052 30916.06765017464 26430.163516447894 28372.736368361097 29539.955452018356 25827.77310450103 29329.710188328834 26040.402699792023 0.8531482784278076 0.8523036308158064 1.167415505743306 1.1872346217757053 1.0149675418291049 1.0895659600758671 1.1343893484509855 0.9918346272236147 1.1263155384522177 1.0 14.668464138671304 -5.249856516994674 24.69567041555183 1.0911843394804952 0.8527258989637778 0.6793155767464618 0.06491121112515201 348.3005146706159 742603.0627666807 0.016569210037122216 0.042981583838177975 5.625271432397419e-06 5.249856516994674 -0.23845844051671738 SCDEPLT(ph)PPPHSPTSMLQLIHDPVSPR ddPTM_PC-9_Lapatinib_30min_R1 1 SCDEPLTPPPHSPTSMLQLIHDPVSPR 27 0 I3VM54;Q9Y2K7;Q9Y2K7-3;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 1 S(0.051)CDEPLT(0.93)PPPHS(0.007)PT(0.007)S(0.004)MLQLIHDPVSPR 53.659 0.0045475 4593200.0 18030.0 12136.0 23731.0 12676.0 21551.0 26037.0 22061.0 18675.0 24683.0 14091.0 True False 17772.888893702948 12107.899837633613 21779.92878430908 13608.235325896392 20283.412550896213 24923.45820521147 23203.210634697974 19542.708676439306 21902.940616487085 16526.61057492273 1.075410400283244 0.7326305525711355 1.3178702726472944 0.8234135646994282 1.2273183578049576 1.5080804434897261 1.4039908866677255 1.1824994960608053 1.325313530998445 1.0 14.012503253716938 -6.451849809230521 6.9103553180518205 1.3098859025206577 0.9947887774007184 0.3475168207034748 0.19228699853630812 0.2677468660444219 22.171056609128062 0.057729151513341646 0.06517959515585735 3.533053311996607e-07 6.451849809230521 -0.31509712511993937 SCDEPLTPPPHS(ph)PTSMLQLIHDPVSPR ddPTM_PC-9_AZD4547_30min_R2 1 SCDEPLTPPPHSPTSMLQLIHDPVSPR 27 0 I3VM54;Q9Y2K7;Q9Y2K7-3;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 1 SCDEPLT(0.002)PPPHS(0.533)PT(0.185)S(0.28)MLQLIHDPVSPR 89.62200000000001 3.0109e-07 10508000.0 16699.0 15129.0 36583.0 62234.0 42442.0 31449.0 25243.0 44215.0 23821.0 34536.0 True False 22008.93463922246 20019.15338628012 36097.88551709241 47886.91280571523 36549.66090224708 29482.489058448442 27489.578097829293 37382.58770962238 25080.12942846466 33326.90515194028 0.6603953934180747 0.6006904420020714 1.0831454451746716 1.4368844807939591 1.0967013209181584 0.8846452715616765 0.8248464108053808 1.1216939448530214 0.7525490084999539 1.0 15.02439972972322 -5.25981652470305 24.905477298265804 1.034506043433247 0.6305428797679119 0.4333979486545446 0.18017557820969995 127.8841048558243 1962554.3961112304 0.05025053940405301 0.11935357088311352 5.497730860553858e-06 5.25981652470305 -0.403963163665335 SCDEPLTPPPHS(ph)PTSMLQLIHDPVSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SCDEPLTPPPHSPTSMLQLIHDPVSPR 27 0 I3VM54;Q9Y2K7;Q9Y2K7-3;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 1 SCDEPLT(0.001)PPPHS(0.533)PT(0.186)S(0.28)MLQLIHDPVSPR 87.80799999999999 4.2906999999999996e-07 7010500.0 45128.0 59664.0 85420.0 87182.0 92875.0 75963.0 84088.0 73432.0 78707.0 56873.0 True False 52767.27908137151 65587.04761436074 87456.73675715418 82297.4751878576 74676.81045876595 71979.36655478123 76122.57589559973 71504.4878076354 79857.94097598495 67183.62469357961 0.785418758247115 0.9762356216042114 1.3017567473627538 1.2249633085921063 1.1115329189123435 1.071382600791111 1.1330525294339229 1.0643142303465016 1.1886518677759963 1.0 16.03582201356162 -4.966734627270646 4.125714100773815 1.1397045027763224 0.8041357211271729 0.6404183202466774 0.08259999536431466 0.1298786751772132 4.873116182950404 0.021557361148758933 0.09610611138104301 1.0796062068517751e-05 4.966734627270646 -0.3355687816491495 SCDEPLTPPPHS(ph)PTSMLQLIHDPVSPR ddPTM_PC-9_Lapatinib_30min_R1 3 SCDEPLTPPPHSPTSMLQLIHDPVSPR 27 0 I3VM54;Q9Y2K7;Q9Y2K7-3;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 1 SCDEPLT(0.021)PPPHS(0.808)PT(0.086)S(0.086)MLQLIHDPVSPR;S(0.005)CDEPLT(0.043)PPPHS(0.543)PT(0.203)S(0.203)MLQLIHDPVS(0.002)PR;SCDEPLT(0.007)PPPHS(0.533)PT(0.179)S(0.281)MLQLIHDPVSPR 100.92 1.0572999999999999e-09 31864400.0 89413.0 65457.0 123864.0 83955.0 94301.0 102099.0 68763.0 69707.0 115861.0 69567.0 True False 88137.95422366388 65305.43833816607 113680.38004886702 90129.33076566989 88754.4005828994 97732.46377439363 72323.21168005696 72945.84169791457 102811.51410958183 81591.56325779908 1.0802336749595132 0.8003944982868524 1.3932859662178452 1.104640322687465 1.0877889458064238 1.1978256068656914 0.8864055153783785 0.8940365741912895 1.2600753068639656 1.0 16.316132361704554 -7.253080148946325 24.9698691194387 1.001299061481778 1.1081189397866789 0.07950755690513744 0.16641438127191566 1671.6216580676912 4993311.122210946 0.06483305812227781 0.049322200769220524 5.5836713870115955e-08 7.253080148946325 0.1068198783049008 SCDEPLTPPPHSPT(ph)SMLQLIHDPVSPR ddPTM_PC-9_AZD4547_30min_R2 1 SCDEPLTPPPHSPTSMLQLIHDPVSPR 27 0 I3VM54;Q9Y2K7;Q9Y2K7-3;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 1 S(0.001)CDEPLT(0.023)PPPHS(0.135)PT(0.604)S(0.237)MLQLIHDPVSPR 73.127 9.5139e-05 13148000.0 20658.0 20345.0 41471.0 72999.0 57565.0 40257.0 33686.0 54072.0 33067.0 46276.0 True False 27226.814286906858 26921.123381840767 40921.06744332999 56170.20837330722 49573.09339422864 37739.723426053584 36683.98874157106 45716.41485094881 34814.85411238155 44655.89132531818 0.6097026277800505 0.6028571501511497 0.9163643637794618 1.2578454198597726 1.110113177074188 0.8451230578093198 0.8214815033995894 1.023748793141418 0.7796251083368895 1.0 15.446562898124306 -5.300320615686188 4.6912445814446135 0.9784926785752656 0.6024153404732319 0.5400715680669411 0.13459884241762032 0.15003733204992026 8.007056951760188 0.0385897438099302 0.08898514231866925 5.008173712496086e-06 5.300320615686188 -0.3760773381020337 SCDEPLTPPPHSPT(ph)SMLQLIHDPVSPR ddPTM_PC-9_Lapatinib_30min_R1 1 SCDEPLTPPPHSPTSMLQLIHDPVSPR 27 0 I3VM54;Q9Y2K7;Q9Y2K7-3;Q9Y2K7-4;Q9Y2K7-2;Q9Y2K7-5 I3VM54;Q9Y2K7-5 KDM2A Lysine-specific demethylase 2A 1 SCDEPLT(0.012)PPPHS(0.096)PT(0.445)S(0.445)MLQLIHDPVS(0.001)PR 58.802 0.0026109 7103900.0 13090.0 15292.0 21389.0 12202.0 17765.0 21418.0 12034.0 14155.0 17519.0 10219.0 True False 12903.334199587993 15256.592313537685 19630.478983927635 13099.375784678748 16720.097627333813 20502.002067796555 12657.061637185778 14812.692975368056 15545.825736751498 11985.34053403841 1.0765930398842216 1.2729377417528445 1.637874111976794 1.0929498204474435 1.3950456876755963 1.710589866810275 1.0560452246842447 1.235900885193871 1.297070007531392 1.0 13.548983279757943 -8.896065379541144 0.7218347818600761 1.001143517889216 1.339046977914603 0.16524882073655045 0.21110162747588235 2.4075065294133853 2.318804719753353 0.22491692238484565 0.07879417572202442 1.2703828448931662e-09 8.896065379541144 0.33790346002538696 SCDS(ph)PLNLK ddPTM_PC-9_AZD4547_30min_R2 1 SCDSPLNLK 9 0 Q8N1G0 Q8N1G0 ZNF687 Zinc finger protein 687 1 S(0.133)CDS(0.867)PLNLK 73.632 0.029071 6532300.0 30170.0 27631.0 33229.0 45464.0 37151.0 34306.0 26132.0 36499.0 30026.0 32769.0 True False 39763.43242501595 36562.18039634518 32788.361748557116 34982.977211797974 31993.224922939076 32160.84039680538 28457.697375608102 30858.91821358152 31613.11306070607 31621.767284107344 1.257470275704688 1.1562345667732752 1.0368921336359365 1.106294183291265 1.0117468968604555 1.0170475327281585 0.8999401304781135 0.9758758242804089 0.9997263206915818 1.0 14.948630379148593 -2.726163187381994 0.4281796634319918 0.9661775543702859 2.9490689039877904 0.8307203214080625 0.03970074717297695 11.051815060446641 0.37806561067863653 0.0277046226603186 16.15256028118719 0.0018786107908389143 2.726163187381994 1.9828913496175047 SCDS(ph)PLNLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SCDSPLNLK 9 0 Q8N1G0 Q8N1G0 ZNF687 Zinc finger protein 687 1 S(0.008)CDS(0.992)PLNLK 99.34299999999999 0.006702199999999999 0.0 28517.0 33229.0 33808.0 31541.0 35728.0 29843.0 33709.0 28988.0 20515.0 20664.0 True False 33344.36486357628 36527.755517189515 34614.110937553996 29773.860027301707 28727.354875593974 28277.980544401005 30515.839487974194 28227.095715324816 20814.993064433052 24410.219623865996 1.3660001989894153 1.4964124075916196 1.4180171858720847 1.2197292972403924 1.176857698056395 1.1584484277541476 1.2501255604492267 1.1563638570349872 0.8527163370575382 1.0 14.575197654956797 -6.333321053326254 0.35921658064587386 0.9580885666771012 1.561652467148876 0.7321132580933307 0.09398356943378466 1.2232740890861553 0.2746320756647745 0.10784838009012448 0.2906249267373655 4.641720079925958e-07 6.333321053326254 0.6035639004717749 SCDS(ph)PLNLK ddPTM_PC-9_Lapatinib_30min_R1 2 SCDSPLNLK 9 0 Q8N1G0 Q8N1G0 ZNF687 Zinc finger protein 687 1 S(0.004)CDS(0.996)PLNLK;S(0.017)CDS(0.983)PLNLK 101.39 0.0035126999999999997 10998700.0 116048.0 109578.0 130733.0 118939.0 103193.0 99703.0 92796.0 92147.0 110283.0 74236.0 True False 114393.1342394033 109324.27887345217 119984.63738397353 127686.17082887309 97123.39062524389 95438.93510904475 97600.52282568485 96428.48601916217 97861.76720852594 87067.5936867476 1.3138428363021921 1.255625362368229 1.378063092172446 1.4665177412420893 1.1154941409621943 1.0961476143743631 1.1209741614869098 1.1075129326083508 1.1239746392970695 1.0 16.40984823124495 -6.32650029110115 8.434096938502156 1.1002525039147628 1.3480648497230403 0.817689363205304 0.059967327291367334 0.1596764071728429 19.415976417662318 0.019348655443461284 0.021961901828377407 4.715195552837777e-07 6.32650029110115 0.2478123458082775 SCFES(ph)SPDPELK ddPTM_PC-9_AZD4547_30min_R2 1 SCFESSPDPELK 12 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SCFES(0.933)S(0.067)PDPELK 215.77 8.4667e-11 508200000.0 126060.0 115970.0 132200.0 175740.0 164920.0 151510.0 134860.0 152830.0 128360.0 141920.0 True False 166144.45778911238 153455.0345830463 130446.94162205445 135225.8581559338 142023.70472641662 142036.0557488482 146862.2787415623 129213.63518402354 135144.84754786635 136951.4239970858 1.21316341911602 1.120507038950626 0.9525051862537058 0.9874001613799304 1.0370370791430306 1.0371272645684253 1.0723676647910385 0.9434997564302295 0.9868086333351459 1.0 17.06330474145019 -5.025049262487794 3.6463599002023863 1.0049312095189613 1.2036029451168773 0.7671055926178274 0.03783020560802955 0.10858325688556741 3.0140451174519445 0.010545513084265077 0.04187321429390595 9.439537965237452e-06 5.025049262487794 0.19867173559791595 SCFES(ph)SPDPELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SCFESSPDPELK 12 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SCFES(0.5)S(0.5)PDPELK;SCFES(0.601)S(0.399)PDPELK;SCFES(0.5)S(0.5)PDPELK;SCFES(0.568)S(0.432)PDPELK 241.35 2.3538e-22 407387000.0 263078.0 265739.0 219621.0 318717.0 323878.0 258273.0 321232.0 296385.0 274245.0 227864.0 True False 307611.909372653 292119.8117121317 224857.59755728013 300860.31978445564 260416.43087767702 244728.70921636844 290802.57944172 288605.20779586537 278255.3143044334 269173.9394295681 1.1427997451185 1.0852455194258046 0.8353616922715366 1.1177171178682346 0.9674652435876595 0.9091842610580955 1.08035190946786 1.0721885202091848 1.0337379424401578 1.0 18.03817921397011 -10.476842225771566 12.02990021512165 1.0000071234093006 1.0235197093596875 0.006432561961892791 0.0917780235411483 0.0 0.0 0.0889318978078977 0.021569153420505763 3.3354756477865257e-11 10.476842225771566 0.023512585950386855 SCFES(ph)SPDPELK ddPTM_PC-9_Lapatinib_30min_R1 3 SCFESSPDPELK 12 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.05)CFES(0.513)S(0.437)PDPELK;SCFES(0.5)S(0.5)PDPELK;SCFES(0.668)S(0.332)PDPELK 283.47 3.8440999999999993e-78 1193762900.0 235073.6 231462.2 237603.2 220790.2 245179.0 235080.0 209530.9 234106.5 220317.6 189111.7 True False 231721.40735678113 230926.2634968948 218068.38207087544 237027.84784251542 230758.0532604606 225026.1763982455 220379.38475943264 244983.9426377965 195503.11184081965 221799.40536949973 1.0447341234786096 1.041149155076365 0.9831783890835564 1.068658626237732 1.0403907660439238 1.0145481500429194 0.9935977258022787 1.104529303086603 0.881441099966555 1.0 17.758895972165362 -8.265736652244318 24.999979457581244 0.940720556958471 1.033796050721286 0.44733184629905076 0.04244106523494717 337.74879605544356 1964861.5155194947 0.03381933877300766 0.009955218928691936 5.423296489020107e-09 8.265736652244318 0.09307549376281499 SCFESS(ph)PDPELK ddPTM_PC-9_AZD4547_30min_R2 3 SCFESSPDPELK 12 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SCFES(0.042)S(0.958)PDPELK;SCFES(0.254)S(0.746)PDPELK;SCFES(0.023)S(0.977)PDPELK 239.48 5.6809e-22 1845440000.0 296932.0 290364.0 329101.0 413210.0 411920.0 350820.0 345929.0 361460.0 321271.0 369060.0 True False 391350.1994307199 384218.4846225021 324736.90570922685 317950.81853086094 354732.0182567653 328883.16994133027 376716.0108467303 305604.662524485 338252.72917225416 356139.32173312065 1.0988682674135746 1.0788431975237576 0.9118254736065742 0.8927708880434243 0.9960484468002387 0.9234677270143866 1.0577770772782826 0.8581042414448559 0.9497764176282951 1.0 18.44208220847389 -5.229453423776838 9.127022348697345 0.9463483128922655 1.0893138933513793 0.5083265791513202 0.055089666020506245 0.3232506619256232 87.46464983408707 0.013679908018136563 0.03574088444557898 5.895852041630492e-06 5.229453423776838 0.14296558045911378 SCFESS(ph)PDPELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SCFESSPDPELK 12 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SCFES(0.017)S(0.983)PDPELK;SCFES(0.031)S(0.969)PDPELK;SCFES(0.312)S(0.688)PDPELK;SCFES(0.097)S(0.903)PDPELK;SCFES(0.106)S(0.894)PDPELK 222.72 1.3831e-12 1262447700.0 432449.0 422703.0 400059.0 510124.0 543746.0 487353.0 514332.0 479104.0 448243.0 364108.0 True False 505654.0744429179 464666.1602931947 409597.92379220674 481543.406124322 437202.87461332127 461795.3507440766 465610.74951878656 466528.0276526497 454797.70588255755 430117.89812265855 1.1756173752590933 1.0803227727126201 0.9522922100660874 1.1195614231031097 1.016472173145053 1.0736483014533482 1.0825188897068552 1.084651509943927 1.0573791694500956 1.0 18.714372640584635 -4.805731085168608 4.271985989571443 1.0527821851814274 1.1819874116351208 0.40478157993824904 0.04600080536864321 0.19334245426547975 6.700608100600017 0.011088224479448187 0.07010426660471272 1.5641158422623335e-05 4.805731085168608 0.12920522645369337 SCFESS(ph)PDPELK ddPTM_PC-9_Lapatinib_30min_R1 2 SCFESSPDPELK 12 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SCFES(0.012)S(0.988)PDPELK;SCFES(0.019)S(0.981)PDPELK 263.44 7.9667e-51 1255830000.0 151153.0 149030.0 152536.0 147243.0 143606.0 145947.0 135698.0 130895.0 147835.0 111601.0 True False 148997.53050193435 148684.9301913757 139995.0788859875 158071.7414082491 135159.3774202588 139705.18702907383 142723.7784645867 136976.85955569084 131184.26552843518 130891.08415101518 1.1383321596605382 1.1359439121142194 1.0695539714872297 1.207658584490555 1.0326095035191174 1.0673392151591425 1.0904010719318329 1.0464949575759814 1.0022398880666443 1.0 16.99800730365891 -7.275723180475182 0.4635921969238332 0.9940821829088419 1.141818351899456 0.5439765576795395 0.0421791215065951 0.8221816096345961 0.3946036933889007 0.042298951592188105 0.04138989950780492 5.300011592601498e-08 7.275723180475182 0.14773616899061415 SCGETFNSIT(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 SCGETFNSITK 11 0 Q5JSP0-2;Q5JSP0-3;Q5JSP0 Q5JSP0-2 FGD3 FYVE, RhoGEF and PH domain-containing protein 3 1 SCGETFNSIT(1)K 113.07 0.0039347 11056000.0 27318.0 33632.0 47049.0 62424.0 48800.0 44334.0 41387.0 55138.0 44779.0 40604.0 True False 36004.555750301144 44502.88629039412 46425.09951872953 48033.111241185965 42024.96234931568 41561.78797154928 45070.36282275726 46617.689045191866 47145.926521859656 39182.46631889572 0.9188945753763839 1.1357857345731355 1.1848437293581249 1.2258827928353766 1.0725451023752726 1.0607241421019518 1.1502686547585217 1.1897589259895698 1.203240401922417 1.0 15.257920589662733 -4.762026731104229 6.580067924858866 1.142676198695449 0.9129333572530443 0.4739249080668463 0.06829037234583997 0.10296309026428348 21.743944413702184 0.017193762770227133 0.10618811257581143 1.729709891184068e-05 4.762026731104229 -0.22974284144240475 SCGETFNSIT(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SCGETFNSITK 11 0 Q5JSP0-2;Q5JSP0-3;Q5JSP0 Q5JSP0-2 FGD3 FYVE, RhoGEF and PH domain-containing protein 3 1 SCGETFNS(0.474)IT(0.526)K 108.68 0.0052679 6230200.0 16643.0 20555.0 15668.0 19897.0 24901.0 15454.0 18451.0 17664.0 12672.0 16101.0 True False 19460.33118576639 22595.564556737492 16041.584541220896 18782.235596944352 20021.82780332418 14643.565034787836 16703.187706328055 17200.338716555038 12857.30402693131 19019.983844554125 1.0231518251966523 1.1879907333994473 0.8434068436821509 0.9875000815167441 1.0526732286924054 0.7699041783876509 0.8781914770716578 0.9043298278867837 0.6759892191292614 1.0 14.215228400333018 -5.767526896277124 0.6165562800769654 0.8423113414561056 1.122008537473904 0.3045118045288818 0.11777193052372587 1.5882305011754672 0.9906263317129198 0.07029032045324238 0.27235340623952736 1.7079419422886223e-06 5.767526896277124 0.2796971960177983 SCGETFNSIT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 SCGETFNSITK 11 0 Q5JSP0-2;Q5JSP0-3;Q5JSP0 Q5JSP0-2 FGD3 FYVE, RhoGEF and PH domain-containing protein 3 1 SCGETFNS(0.006)IT(0.994)K 111.72 0.0043457 9740800.0 35085.0 31312.0 31438.0 27103.0 32598.0 39508.0 38004.0 31935.0 34670.0 29999.0 True False 34584.68146619899 31239.49898780354 28853.28899418943 29096.24503295757 30680.649730133842 37818.334937646214 39971.66116499986 33418.816684449244 30765.099508714764 35184.28717884512 0.9829581395354614 0.8878821056970732 0.8200617749487258 0.8269670175512879 0.8719986161487695 1.0748643206955415 1.1360656807346998 0.9498221895068721 0.8743988290094609 1.0 15.102643664372387 -6.744485094247715 24.676674155666745 1.011958798869155 0.8724729385968721 0.4099123333948076 0.07716781343768604 217.45888283447712 316506.9289308189 0.027823109976483833 0.027751702751574524 1.801004947046133e-07 6.744485094247715 -0.13948586027228282 SCGTDSQSENEAS(ph)PVKRPR ddPTM_PC-9_AZD4547_30min_R2 2 SCGTDSQSENEASPVKRPR 19 2 H0Y398;C9JQ48;Q9H8U3 H0Y398 ZFAND3 AN1-type zinc finger protein 3 1 SCGTDSQS(0.003)ENEAS(0.997)PVKRPR;SCGTDSQSENEAS(1)PVKRPR 97.62100000000001 0.00019043 5728200.0 43291.0 29198.7 47347.0 75253.0 66593.0 52586.0 43010.0 51644.0 44841.0 49983.0 True False 57056.6374912617 38636.60876330079 46719.14784401978 57904.583497260166 57347.711428852 49297.78910704856 46837.80667858963 43663.60646105934 47211.20371528415 48233.110383641164 1.1829350634333784 0.8010391296764652 0.9686115507049103 1.2005152277490112 1.18896979632278 1.0220736070085268 0.9710716623092843 0.9052620930676777 0.978813170864809 1.0 15.557736226977996 -7.196281444075733 3.87165207058067 0.9549658731134318 1.0588489949684703 0.14862076057438667 0.11520527209765143 0.512959278544419 15.30077294012988 0.050981170076094484 0.03779465876293238 6.363829799376712e-08 7.196281444075733 0.10388312185503845 SCGTDSQSENEAS(ph)PVKRPR ddPTM_PC-9_Lapatinib_30min_R1 1 SCGTDSQSENEASPVKRPR 19 2 H0Y398;C9JQ48;Q9H8U3 H0Y398 ZFAND3 AN1-type zinc finger protein 3 1 SCGTDSQSENEAS(1)PVKRPR 69.111 0.0025475000000000003 2824500.0 19988.0 15146.0 18848.0 15187.0 13752.0 13916.0 13944.0 11697.0 16396.0 13963.0 True False 19702.967454649715 15110.930367567464 17298.39019538399 16303.902642346844 12943.134397472262 13320.84511978042 14665.952091484005 12240.48532199789 14549.309822465753 16376.485945471999 1.2031254763844785 0.9227211758298822 1.0562943877570323 0.9955678340660608 0.790348701215169 0.8134129119112733 0.8955493956589053 0.747442727502985 0.8884268499914996 1.0 13.999338197277497 -6.1186967098677245 4.408725902760926 0.8436518677646309 1.0442961507749162 0.5111015948589108 0.09093009710355893 0.17980726049278453 5.659566676482389 0.025760372085863726 0.034070916473014703 7.608574372592385e-07 6.1186967098677245 0.20064428301028536 SCLQCRPPS(ph)PPESSVPQQQVK ddPTM_PC-9_AZD4547_30min_R2 2 SCLQCRPPSPPESSVPQQQVK 21 1 P41002 P41002 CCNF Cyclin-F 1 SCLQCRPPS(1)PPESSVPQQQVK;S(0.001)CLQCRPPS(0.987)PPES(0.011)S(0.002)VPQQQVK 102.16 6.9912e-05 18132500.0 28060.0 25610.3 34458.0 31128.0 32376.0 28075.0 28560.0 34883.0 28475.0 34987.0 True False 36982.4963157424 33888.32863828738 34001.06440554278 23951.920522805904 27881.151250439467 26319.46581182042 31101.78467194887 29492.63388159579 29980.13036713534 33762.11577921398 1.0953844408800673 1.003738298271908 1.0070774186040767 0.709431857868107 0.8258117303064522 0.7795561742615755 0.9212036613859677 0.8735422292388814 0.8879813860952678 1.0 15.04311769616961 -5.601598136125862 8.824521536626001 0.8498054924735875 1.0386197348853132 0.5325032119943067 0.07703728176807075 0.20505610777924588 20.69651227848693 0.020838259967954135 0.036161077109134 2.5026600664463296e-06 5.601598136125862 0.18881424241172573 SCLQCRPPS(ph)PPESSVPQQQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SCLQCRPPSPPESSVPQQQVK 21 1 P41002 P41002 CCNF Cyclin-F 1 S(0.001)CLQCRPPS(0.999)PPES(0.001)SVPQQQVK;S(0.005)CLQCRPPS(0.993)PPES(0.001)SVPQQQVK 71.592 0.0011184 14741600.0 26516.1 32649.9 25423.1 27952.0 34503.6 28064.5 28713.7 27861.4 25721.9 18933.5 True False 31004.7520131527 35891.16629632809 26029.283121643643 26385.940061606707 27742.867266165045 26592.748215271346 25993.730466814362 27130.067771593443 26098.034126446033 22365.99367249648 1.3862452286785418 1.6047203992757788 1.1637883611516855 1.1797347548235053 1.240403966503868 1.1889812992289504 1.1621987758486636 1.2130052511351355 1.1668622690588906 1.0 14.449019235121442 -1.522878745532037 0.2990932937518112 1.1058718957926987 4.511203919474761 0.5666217975948649 0.10098168776055595 39.420171648816265 0.5616009870877343 0.1031582888138255 71.74719605778064 0.029999999982613223 1.522878745532037 3.4053320236820626 SCLQCRPPS(ph)PPESSVPQQQVK ddPTM_PC-9_Lapatinib_30min_R1 2 SCLQCRPPSPPESSVPQQQVK 21 1 P41002 P41002 CCNF Cyclin-F 1 S(0.024)CLQCRPPS(0.951)PPES(0.012)S(0.012)VPQQQVK;SCLQCRPPS(0.999)PPESSVPQQQVK 107.18 3.1634e-05 17367200.0 17690.4 19172.9 22671.0 19994.1 20724.7 16720.9 23026.0 17181.8 20095.7 17004.6 True False 17438.13165197796 19128.50632802947 20807.07789259076 21464.53281236235 19505.713892327905 16005.786085321683 24218.173612916715 17980.129153244725 17832.310648897594 19943.82245279476 0.8743625597977748 0.9591193650718126 1.043284352427387 1.0762496940176325 0.9780328689997206 0.8025435506762028 1.2143195553529902 0.9015387695012869 0.894127025604298 1.0 14.28365432414951 -6.521048989187111 24.995730780235107 0.9630012138912335 0.9947333930280144 0.010563373377513119 0.11115636102406044 455.16192739175534 6217961.212246676 0.03701838047234533 0.03759024932253448 3.0126661709360504e-07 6.521048989187111 0.03173217913678095 SCLVRPLMNDEGLK ddPTM_PC-9_Lapatinib_30min_R1 1 SCLVRPLMNDEGLK 14 1 P30838;A8MYB8;I3L3I9 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 0 73.415 0.026617000000000002 4392500.0 15848.0 19928.0 13462.0 15782.0 16753.0 14781.0 13545.0 9660.5 15386.0 10213.0 False True 15622.004613832736 19881.85794037267 12355.206324822751 16942.660927208657 15767.621477665256 14148.851086193894 14246.293823806001 10109.362097389134 13653.066658237256 11978.303442032911 1.3041917571576755 1.6598225313449229 1.0314654645888544 1.414445794364783 1.3163484757228054 1.1812066003057111 1.1893415367834574 0.8439727834840534 1.1398163958952197 1.0 13.548135964713488 -7.151647773035426 1.1968726575307431 0.9947014543479559 1.3602161092150207 0.444777740821928 0.16332087412496785 0.43015675772145 1.2254282043924556 0.09938334619197617 0.0624829325942259 7.052648298164518e-08 7.151647773035426 0.3655146548670648 SCMLT(ph)GTPESVQSAK ddPTM_PC-9_AZD4547_30min_R2 1 SCMLTGTPESVQSAK 15 0 Q96AE4;E9PEB5;Q96AE4-2;C9JSZ1 Q96AE4 FUBP1 Far upstream element-binding protein 1 1 SCMLT(0.946)GT(0.054)PESVQSAK 146.27 0.00044366 18081000.0 59747.0 62423.0 78548.0 91477.0 83432.0 85630.0 68101.0 85467.0 69488.0 75439.0 True False 78745.30318519824 82600.01400170289 77506.4021976486 70388.39095556138 71848.9069411498 80275.54256335448 74161.85707088202 72260.03898627816 73160.99381743633 72797.90357184452 1.0816974022814299 1.1346482515143397 1.0646790414940623 0.9669013460819625 0.9869639565958359 1.1027177792850895 1.018736164533796 0.9926115374320423 1.0049876470032337 1.0 16.151609283956212 -5.534927949996604 6.826458187829838 1.0133229008141573 1.106427031768506 0.5484933970960757 0.03600215337466282 0.10799599576832261 24.407291253631183 0.010274440780973122 0.01868260947715832 2.9179110589804742e-06 5.534927949996604 0.09310413095434877 SCMLT(ph)GTPESVQSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SCMLTGTPESVQSAK 15 0 Q96AE4;E9PEB5;Q96AE4-2;C9JSZ1 Q96AE4 FUBP1 Far upstream element-binding protein 1 1 SCMLT(0.984)GT(0.016)PESVQSAK;SCMLT(0.787)GT(0.213)PESVQSAK 198.38 2.8067e-09 36745000.0 109766.0 142084.0 112506.0 129884.0 144730.0 114998.0 130020.0 114955.0 108010.0 100065.0 True False 128347.21582267826 156189.16051955707 115188.56972138124 122607.0205696097 116371.19545299842 108967.3024375911 117703.56433671762 111937.55305489025 109589.4419151556 118205.99238589584 1.0857928031573505 1.3213303096315219 0.9744731836042296 1.037231853435537 0.9844779702292289 0.9218424568684804 0.9957495551702829 0.9469702068018547 0.9271056373977167 1.0 16.850943648414862 -5.281448406631186 24.825606638969802 0.9732080054241651 1.203561541718972 0.6866887563703872 0.062164967468177006 329.0397882018912 408246.0081779435 0.015375464875491374 0.03207614563063519 5.230601010489905e-06 5.281448406631186 0.23035353629480693 SCMLT(ph)GTPESVQSAK ddPTM_PC-9_Lapatinib_30min_R1 1 SCMLTGTPESVQSAK 15 0 Q96AE4;E9PEB5;Q96AE4-2;C9JSZ1 Q96AE4 FUBP1 Far upstream element-binding protein 1 1 SCMLT(0.996)GT(0.004)PESVQSAK 159.18 0.0009969 17715000.0 48195.0 70302.0 76196.0 65758.0 78879.0 86951.0 68086.0 65946.0 77485.0 58317.0 True False 47507.73046211944 70139.22003834203 69931.45900506589 70594.06268225738 74239.49230208073 83232.30842268081 71611.15993264336 69010.09190770914 68757.82334677721 68397.01574748187 0.6945877673598428 1.025471934291582 1.0224343597569974 1.0321219706849039 1.0854200507251512 1.2168997069984757 1.0469924623177704 1.0089634928297269 1.005275195055694 1.0 16.061645759335597 -4.747601511103073 3.7730293220388536 1.0573090790492792 0.6424813369330269 0.7562899398247883 0.06050430639751323 0.15745681162165412 3.7794217431950896 0.01665830118321683 0.1915885723634977 1.7881275269908525e-05 4.747601511103073 -0.4148277421162523 SCMLTGT(ph)PESVQSAK ddPTM_PC-9_AZD4547_30min_R2 3 SCMLTGTPESVQSAK 15 0 Q96AE4;E9PEB5;Q96AE4-2;C9JSZ1 Q96AE4 FUBP1 Far upstream element-binding protein 1 1 S(0.002)CMLT(0.082)GT(0.915)PES(0.001)VQSAK;SCMLTGT(1)PESVQSAK;SCMLT(0.371)GT(0.629)PESVQSAK 155.06 0.00023577 40860000.0 121909.0 130665.0 156042.0 194018.0 166553.0 162892.0 124710.0 156414.0 136867.0 144245.0 True False 160673.52613527616 172899.90595665903 153972.78112396834 149290.14764821882 143429.99086404903 152706.3374895474 135808.9484047176 132243.81033615014 144101.51020048172 139195.02645476098 1.1543050799124335 1.2421414066317398 1.1061658239205134 1.072525013648665 1.0304246819527307 1.0970674842263684 0.9756738574912813 0.9500613183124756 1.035248987486743 1.0 17.08674813794213 -5.7504839376849395 0.6913811338263164 0.9933409495304274 1.2305812091908253 0.7333108623823341 0.0430865849964098 0.5728667024793291 0.4612376277135838 0.02344868206254445 0.08916016738903858 1.7762989632193392e-06 5.7504839376849395 0.23724025966039786 SCMLTGT(ph)PESVQSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SCMLTGTPESVQSAK 15 0 Q96AE4;E9PEB5;Q96AE4-2;C9JSZ1 Q96AE4 FUBP1 Far upstream element-binding protein 1 1 SCMLT(0.119)GT(0.872)PES(0.008)VQSAK;SCMLT(0.123)GT(0.877)PESVQSAK;SCMLT(0.119)GT(0.881)PESVQSAK;SCMLT(0.073)GT(0.927)PESVQSAK 167.92 1.4452000000000002e-06 41178200.0 155460.0 170875.0 142331.0 172283.0 192815.0 155568.0 173587.0 155697.0 148078.0 126539.0 True False 181776.30752504026 187838.34072646662 145724.71083332365 162630.54205902247 155034.28488405855 147409.74021818765 157143.58269895226 151610.11872460746 150243.36061394642 149479.51901782706 1.2160616298434936 1.2566159027048036 0.9748807849451563 1.087978762091327 1.0371607154125846 0.9861534288226298 1.05127166404791 1.0142534557294522 1.0051100083886961 1.0 17.189588301097167 -5.256857379437623 24.99998345178032 1.0231158728987937 1.2363387890196904 0.8757513236738047 0.03263353509399126 114.04305742790123 622228.0530095337 0.008145771828847195 0.020154751774546495 5.53531857008614e-06 5.256857379437623 0.21322291612089672 SCMLTGT(ph)PESVQSAK ddPTM_PC-9_Lapatinib_30min_R1 3 SCMLTGTPESVQSAK 15 0 Q96AE4;E9PEB5;Q96AE4-2;C9JSZ1 Q96AE4 FUBP1 Far upstream element-binding protein 1 1 SCMLT(0.235)GT(0.765)PES(0.001)VQSAK;SCMLT(0.055)GT(0.945)PESVQSAK;SCMLT(0.027)GT(0.972)PESVQSAK 156.29 5.941e-05 51546000.0 116052.0 154060.0 153197.0 141055.0 138784.0 147584.0 135633.0 125446.0 144395.0 115644.0 True False 114397.07719866966 153703.28353541807 140601.73401752132 151428.6552456861 130620.99797984232 141272.17635510725 142655.4130826342 131274.67912313816 128131.71455324108 135632.9113140561 0.843431554261818 1.1332299959227468 1.0366343437984602 1.1164595213550725 0.9630479557973302 1.0415774090994294 1.051775794683914 0.9678674434641713 0.9446948628607837 1.0 17.049347765215515 -7.772731410450621 23.968424390182257 0.9672108022175909 1.032669957908729 0.0942511306152446 0.07735246167832831 280.13329501885244 594594.3829093479 0.039684648763448814 0.019368758262993814 1.6875963972042123e-08 7.772731410450621 0.06545915569113814 SCMTDAKKLY(ph)T(ph)LFY(ph)VHGS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 SCMTDAKKLYTLFYVHGSK 19 2 Q9H3C7-3;Q9H3C7;A0A087X1D7;Q9H3C7-2 Q9H3C7-3 GGNBP2 Gametogenetin-binding protein 2 4 S(0.001)CMT(0.003)DAKKLY(0.999)T(0.998)LFY(0.999)VHGS(1)K 51.888000000000005 0.017956 12288000.0 11707.0 6285.7 13166.0 25798.0 21683.0 17046.0 18250.0 11925.0 10738.0 13806.0 True False 15429.582479272838 8317.429601437036 12991.41023748842 19850.66967512679 18672.68972582403 15980.110925317562 19874.214645065367 10082.265259238877 11305.588757938516 13322.656142219346 1.15814611700265 0.6243071586212599 0.9751366468371715 1.4899933964534475 1.4015740950222748 1.1994688412528167 1.4917606844241973 0.7567759125215499 0.8485987056373266 1.0 13.70159412120701 -7.788620153429718 24.997828682783833 0.8520153241382076 1.1812171112777872 0.2582879846816113 0.24996051901668284 351.35191594599286 323129.12938593165 0.15198592252929113 0.07304042685386425 1.626971129849215e-08 7.788620153429718 0.3292017871395796 SCNCLLLK ddPTM_PC-9_Lapatinib_30min_R1 2 SCNCLLLK 8 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 ; 115.49 0.016732 104015000.0 337940.0 296150.0 307480.0 290180.0 300610.0 258600.0 288040.0 238650.0 234150.0 229460.0 False True 333120.91362939327 295464.2828704025 282200.1813071238 311520.80521210283 282928.710821999 247540.2808260433 302953.3018094558 249738.55023465824 207777.56129119027 269121.8552637687 1.2378069900822382 1.0978828998515018 1.0485962986192143 1.1575455471900584 1.0513033604970436 0.9198074254631862 1.1257105132265404 0.9279757305102081 0.7720575539565364 1.0 18.037900030782417 -6.626764877362723 0.5447643582828849 0.9041143524519488 1.1735127883098284 0.4886478381193011 0.09153581029676099 0.9002138958595665 0.5746928029996776 0.07857739175352238 0.11031494025957603 2.3617565182011497e-07 6.626764877362723 0.2693984358578796 SCPETLTHAVGMS(ph)ESPIGPK ddPTM_PC-9_AZD4547_30min_R2 2 SCPETLTHAVGMSESPIGPK 20 0 Q68CZ2;Q68CZ2-2;E9PCX8 Q68CZ2 TNS3 Tensin-3 1 SCPETLTHAVGMS(0.628)ES(0.372)PIGPK;SCPETLTHAVGMS(0.719)ES(0.281)PIGPK 94.456 0.00040046 45457000.0 105711.0 107027.0 153001.0 236250.0 203518.0 203734.0 139979.0 198071.0 149107.0 183141.0 True False 139324.8990746061 141621.38472294298 150972.10677092266 181786.21252611466 175263.038676394 190994.48077312234 152436.85982474507 167463.67816878055 156988.4916120264 176729.28933378222 0.7883520586758441 0.8013464279566461 0.8542562884739897 1.0286139508136742 0.9917034088525136 1.0807177547825588 0.8625444056239205 0.9475717284897692 0.8882992298776685 1.0 17.43118163189792 -5.588001068525687 4.784137016384169 0.9696522043987279 0.8013240102484057 0.5969624968904537 0.06015323470302385 0.1424156966632019 6.373147795710714 0.01742923793133614 0.03149307568666309 2.5822538373235043e-06 5.588001068525687 -0.16832819415032219 SCPETLTHAVGMSES(ph)PIGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SCPETLTHAVGMSESPIGPK 20 0 Q68CZ2;Q68CZ2-2;E9PCX8 Q68CZ2 TNS3 Tensin-3 1 SCPETLTHAVGMS(0.259)ES(0.741)PIGPK;SCPETLTHAVGMS(0.026)ES(0.974)PIGPK 112.88 2.3691e-05 24735000.0 48108.0 50314.0 57666.0 68562.0 96214.0 92817.0 93431.0 84643.0 83309.0 59724.0 True False 56251.734223688625 55308.84140635807 59040.97613952287 64720.69342100305 77361.55737797804 87949.51312500994 84580.53929813755 82421.2109366715 84527.23651985645 70551.48842507624 0.797314634735544 0.7839500291350274 0.8368494762831656 0.9173540468920747 1.0965262265180118 1.246600391973444 1.1988484039987304 1.1682419857690258 1.1980928879994088 1.0 16.106388899236975 -6.171334327946415 1.9469886549560702 1.1762769988883621 0.8006184896978956 0.8655414363197187 0.06271085386484285 0.10510164398329715 0.7845261276505351 0.02033581887179131 0.02843696055182632 6.740089633310045e-07 6.171334327946415 -0.3756585091904665 SCPETLTHAVGMSES(ph)PIGPK ddPTM_PC-9_Lapatinib_30min_R1 3 SCPETLTHAVGMSESPIGPK 20 0 Q68CZ2;Q68CZ2-2;E9PCX8 Q68CZ2 TNS3 Tensin-3 1 SCPETLTHAVGMS(0.174)ES(0.826)PIGPK;SCPETLTHAVGMS(0.463)ES(0.537)PIGPK;SCPETLTHAVGMS(0.234)ES(0.766)PIGPK 90.084 0.00047141 24941000.0 136108.0 110693.0 161426.0 101095.0 173085.0 176408.0 146703.0 142153.0 177910.0 120630.0 True False 134167.0749608495 110436.69715945788 148154.1774023799 108529.86354303361 162904.48059820273 168863.44106713292 154298.56351670792 148757.94733504023 157871.90232464529 141480.7347706284 0.948306320138668 0.7805776336863123 1.0471685607412955 0.7670999427518139 1.1514251806954987 1.1935437099679893 1.0905976970423574 1.05143606708157 1.1158544135396993 1.0 17.11024609114687 -6.2745866940843635 24.974672507909442 1.1072074414403303 0.8898002519742099 0.5809869674411653 0.08918318536203447 523.7159699480281 994849.9874827049 0.02642875489183274 0.030145075972830008 5.313899125950405e-07 6.2745866940843635 -0.21740718946612048 SCPS(ph)FSASSEGTR ddPTM_PC-9_AZD4547_30min_R2 1 SCPSFSASSEGTR 13 0 D6RCP9;D6RFG8;P27707;D6RG38 D6RCP9 DCK Deoxycytidine kinase 1 SCPS(0.98)FS(0.019)ASSEGTR 125.61 0.0001394 8396400.0 16361.0 18097.0 19801.0 27155.0 22552.0 21979.0 22577.0 24921.0 19905.0 23154.0 True False 21563.457670059208 23946.501343876746 19538.425802256425 20894.834290567796 19421.04407585589 20604.649655494235 24586.309262555653 21070.032077609387 20957.137663137113 22343.38550752911 0.9650935693157562 1.0717490120647755 0.8744612939553189 0.9351686781542935 0.8692077603598403 0.9221811819229916 1.1003842391866148 0.9430098259061663 0.9379571263305254 1.0 14.447560181524176 SCPS(ph)FSASSEGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SCPSFSASSEGTR 13 0 D6RCP9;D6RFG8;P27707;D6RG38 D6RCP9 DCK Deoxycytidine kinase 1 S(0.07)CPS(0.825)FS(0.051)AS(0.038)S(0.015)EGT(0.001)R;SCPS(0.999)FS(0.001)ASSEGTR 139.74 6.977e-05 10306800.0 19903.8 21026.9 23292.3 24931.0 31992.0 27981.0 30541.0 27234.0 22731.0 12443.7 True False 23273.12022203071 23114.311670059036 23847.67676853965 23534.19689739254 25723.397256493576 26513.627102264694 27647.935382308006 26519.13635680821 23063.397872172947 14699.644305725002 1.5832437668554087 1.5724402025875424 1.6223301919796664 1.601004514662085 1.7499333127724188 1.8036917459246653 1.88085744166885 1.8040665342140234 1.568976595113295 1.0 13.843493625456318 -8.640251835405312 5.36246553753475 1.0000094307385996 1.7021887466965746 0.8113483671101067 0.10125974175679714 0.6757218545137594 30.588791416259753 0.11428255329536112 0.029676113691541453 2.2895396268090165e-09 8.640251835405312 0.702179315957975 SCPS(ph)FSASSEGTR ddPTM_PC-9_Lapatinib_30min_R1 2 SCPSFSASSEGTR 13 0 D6RCP9;D6RFG8;P27707;D6RG38 D6RCP9 DCK Deoxycytidine kinase 1 SCPS(0.803)FS(0.039)AS(0.134)S(0.024)EGTR;S(0.119)CPS(0.858)FS(0.023)ASSEGTR 120.6 0.00021005 10365700.0 17498.199999999997 14849.900000000001 20519.2 20440.7 19398.2 22055.0 22356.0 21703.1 28215.0 19404.199999999997 True False 17248.67245922313 14815.51596892513 18832.19058240254 21943.977266176284 18257.23601432857 21111.759062716086 23513.484291251898 22711.505257061868 25037.129582878206 22758.190115528738 0.7579105531530707 0.6509971088964569 0.8274906961759079 0.9642233039965297 0.8022270629451766 0.9276554486778265 1.0331877962126608 0.9979486568031166 1.1001371135305906 1.0 14.474098208934933 -5.902154626343237 0.4725866803313746 1.0545252998208872 0.6274927853408274 0.7379016604208543 0.06847670979500342 0.9457208962299867 0.338525419006188 0.057375363985899874 0.2036759355454167 1.252695085582964e-06 5.902154626343237 -0.42703251448005974 SCQGACGPS(ph)PPDQK ddPTM_PC-9_AZD4547_30min_R2 4 SCQGACGPSPPDQK 14 0 P18754-2 P18754-2 RCC1 Regulator of chromosome condensation 1 SCQGACGPS(1)PPDQK;SCQGACGPS(1)PPDQK;SCQGACGPS(1)PPDQK;SCQGACGPS(1)PPDQK 184.92 6.220599999999999e-06 28759200.0 80278.0 76236.0 91102.0 110057.0 104180.0 101853.0 84530.0 96163.0 85543.0 89058.0 True False 105804.73411386923 100877.79612376561 89893.92795501076 84685.05901369984 89716.40527769894 95484.11580877435 92053.00624369166 81303.2179559066 90064.62834050419 85940.10652714562 1.2311450193565798 1.173815116134417 1.0460067084815197 0.9853962536915246 1.0439410527069863 1.1110541942208798 1.071129766573133 0.9460451149222816 1.047992979995385 1.0 16.3910439449565 -5.178381382821379 2.9149001504804533 1.0313588141351522 1.2230456318705505 0.7188430348401634 0.04353308692067956 0.15216420853671536 2.447333215644745 0.012436096054212272 0.04338623836483967 6.631604493962966e-06 5.178381382821379 0.1916868177353983 SCQGACGPS(ph)PPDQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SCQGACGPSPPDQK 14 0 P18754-2 P18754-2 RCC1 Regulator of chromosome condensation 1 SCQGACGPS(1)PPDQK;SCQGACGPS(1)PPDQK 171.26 3.4483e-05 11067600.0 48895.0 56290.0 48311.0 64444.0 64621.0 62069.0 63625.0 56099.0 51785.0 48798.0 True False 57171.95777973007 61878.09919234994 49462.91746048777 60833.411610266965 51958.978935729945 58813.99237377032 57597.979394890346 54626.46069180378 52542.25765740509 57644.69111524454 0.9917991869438703 1.0734396870761589 0.8580654437301158 1.0553168111985798 0.9013662477929217 1.0202846304820696 0.999189661364291 0.9476407911110731 0.9114847636595268 1.0 15.814900126118822 -5.193797895132988 24.999988743878937 0.9644209301830728 1.0326193690898342 0.18353187805957283 0.05963338630445367 298.68207643107155 110389.64132061752 0.014138062044335644 0.03740579292472192 6.400326141055814e-06 5.193797895132988 0.06819843890676136 SCQGACGPS(ph)PPDQK ddPTM_PC-9_Lapatinib_30min_R1 3 SCQGACGPSPPDQK 14 0 P18754-2 P18754-2 RCC1 Regulator of chromosome condensation 1 SCQGACGPS(1)PPDQK;SCQGACGPS(1)PPDQK;SCQGACGPS(1)PPDQK 162.26 4.3879e-05 21539300.0 65479.0 67103.0 61850.0 61156.0 69900.0 62695.0 59053.0 62804.0 64212.0 51644.0 True False 64545.257452622034 66947.6271262961 56764.93174790427 65653.61625043543 65788.61942868751 60013.68099918322 62110.475391451844 65722.10311727418 56979.768377663524 60570.59658869557 1.0656203023872521 1.1052826106518931 0.9371697646197271 1.0839189301082188 1.0861477867788707 0.99080551256092 1.0254228766015434 1.0850496250443082 0.9407166444898083 1.0 15.886330000801538 -8.266013950676857 24.98849357634963 0.9703583208415757 1.0455666570309128 0.27048516475888174 0.05055341312952858 563.0529773967687 3075610.7246784098 0.04304559575183447 0.012525404518697 5.419834801923059e-09 8.266013950676857 0.07520833618933709 SCQSQPSQTKPS(ph)PCK ddPTM_PC-9_AZD4547_30min_R2 1 SCQSQPSQTKPSPCK 15 1 Q9BX69 Q9BX69 CARD6 Caspase recruitment domain-containing protein 6 1 SCQSQPS(0.002)QT(0.008)KPS(0.99)PCK 52.81399999999999 0.039501 4360500.0 8542.7 7951.3 7075.0 16253.0 9374.5 15377.0 10850.0 13152.0 9333.1 11792.0 True False 11259.100900801584 10521.402228853804 6981.180877277125 12506.121956346842 8073.012490648775 14415.473759158062 11815.628980764885 11119.660602893899 9826.42861209872 11379.165669205464 0.9894487195376018 0.9246198301978362 0.6135055135166669 1.0990368116522964 0.7094555721687162 1.2668304670323518 1.0383563544329604 0.9771947193796604 0.8635456146570751 1.0 13.474107161356836 -6.742590083903917 24.999987592860034 1.0283334270429518 0.8691868233675184 0.20855567592002688 0.1577365607460447 410.9782488526611 545083.0465767412 0.05140866135890186 0.0513262023034206 1.8088806627203964e-07 6.742590083903917 -0.15914660367543343 SCQSQPSQTKPS(ph)PCK ddPTM_PC-9_Lapatinib_30min_R1 2 SCQSQPSQTKPSPCK 15 1 Q9BX69 Q9BX69 CARD6 Caspase recruitment domain-containing protein 6 1 S(0.001)CQSQPS(0.001)QTKPS(0.998)PCK;SCQSQPSQT(0.006)KPS(0.994)PCK 67.32600000000001 0.014183000000000001 10191900.0 28269.0 31774.0 31123.1 32700.0 34358.0 31837.0 25004.9 25813.7 30880.7 26310.4 True False 27865.878876100316 31700.42925518873 28564.27885664024 35104.86708400221 32337.129990426984 30475.405725671815 26299.531372084646 27013.098739544937 27402.59037781278 30858.117583595675 0.903032364194307 1.0272962752608354 0.9256649819697735 1.1376217939704827 1.047929443616404 0.9875976926691306 0.8522727059043163 0.8753968438407025 0.8880188593350921 1.0 14.913362436414568 -7.127904391337434 5.274508196819201 0.8941936546748609 1.0123943673641569 0.3260932212773112 0.07077957086764299 0.24874564701551297 9.637285615010281 0.027578783192026283 0.021276657626682877 7.448959425242549e-08 7.127904391337434 0.118200712689296 SCS(ph)ASCVPHGAK ddPTM_PC-9_AZD4547_30min_R2 3 SCSASCVPHGAK 12 0 P00519-2;P00519 P00519-2 ABL1 Tyrosine-protein kinase ABL1 1 S(0.002)CS(0.996)AS(0.001)CVPHGAK;S(0.087)CS(0.912)AS(0.001)CVPHGAK;SCS(1)ASCVPHGAK 122.45 0.00040038 2743300.0 19907.7 20822.300000000003 41585.0 63524.0 44934.0 39922.0 32073.9 59197.0 33488.0 39453.0 True False 26237.934494116344 27552.701272730574 41033.5557288437 48879.523236016525 38695.6897172982 37425.671029011384 34928.41496462256 50049.46386173283 35258.10731289299 38071.76247855859 0.6891704713931521 0.7237043803330045 1.0777950128248763 1.283878655829099 1.0163881889915394 0.9830296417217073 0.9174362490912705 1.314608534078765 0.9260960096803976 1.0 15.21643373852815 -5.251385098894495 6.485867013708345 1.0744307342560364 0.7031984341455988 0.5527526758027851 0.1288039869883694 0.1036115578759297 22.520670084489367 0.03327873010098477 0.08200856248501909 5.605507024072791e-06 5.251385098894495 -0.3712323001104376 SCS(ph)ASCVPHGAK ddPTM_PC-9_Lapatinib_30min_R1 1 SCSASCVPHGAK 12 0 P00519-2;P00519 P00519-2 ABL1 Tyrosine-protein kinase ABL1 1 S(0.012)CS(0.891)AS(0.097)CVPHGAK 114.87 0.00074897 2017700.0 10109.0 9211.9 14431.0 8203.7 14135.0 13814.0 14574.0 13633.0 15960.0 12080.0 True False 9964.843806236442 9190.570411527448 13244.53888527093 8807.027464740948 13303.607090479221 13223.207422006808 15328.570408870319 14266.438949713372 14162.416733749295 14168.011904411795 0.7033339521075274 0.6486845489355909 0.9348198586102752 0.6216134997739885 0.9389889830863705 0.9333142512316225 1.0819139983992487 1.0069471317476044 0.9996050842771556 1.0 13.790349708950435 -6.441713505699781 4.11441127477851 1.0046484642884492 0.7366968769914118 0.7008343548605651 0.08577337815208941 0.1324601679910312 4.1435710164454695 0.02735081765179931 0.03062355200853975 3.61648355251507e-07 6.441713505699781 -0.2679515872970374 SCS(ph)FSSESR ddPTM_PC-9_AZD4547_30min_R2 2 SCSFSSESR 9 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 S(0.013)CS(0.977)FS(0.009)S(0.001)ESR;S(0.047)CS(0.929)FS(0.024)S(0.001)ESR 85.963 0.012029999999999999 37075200.0 48094.0 57236.0 72273.0 66886.0 55932.0 49033.0 64353.0 68799.0 51003.0 47658.0 True False 63386.89158265553 75736.41768901634 71314.61279766071 51466.466078398735 48166.80725659686 45966.95875871739 70080.29233172015 58167.69539374219 53698.91445531185 45989.5079259662 1.378290276223342 1.6468194834990764 1.5506713599211106 1.119091471064429 1.0473433926306772 0.9995096888776216 1.523832184604698 1.2648036044956257 1.167634029521608 1.0 15.489017140942742 -5.757321265730979 24.997817819425965 1.175088818163957 1.5374163814957336 0.5281307318612669 0.15752170407142738 87.20579487674405 529348.2493061761 0.04569395296328364 0.07560987813893238 1.7485527327457055e-06 5.757321265730979 0.3623275633317766 SCS(ph)FSSESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SCSFSSESR 9 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 S(0.014)CS(0.981)FS(0.002)S(0.003)ESR 101.3 0.0035443000000000007 11485000.0 36154.0 40865.0 37312.0 34300.0 52500.0 31215.0 33059.0 30671.0 32678.0 29117.0 True False 42274.15812595074 44921.80713262356 38201.659586548005 32378.282202100367 42213.00187440341 29578.030449133046 29927.412193566666 29865.918748610722 33155.85392929774 34395.68160995482 1.22905423434655 1.3060304384147532 1.1106527854209365 0.9413473054341048 1.2272762131332815 0.8599344180628928 0.8700921392674205 0.8683043146895192 0.9639539726318942 1.0 15.069939824971494 -5.637350966597169 0.6893770244893072 0.9104311102704713 1.33822710409235 0.5872114764229468 0.1024781423186081 0.868373547895343 0.6428896983841416 0.05428535551369355 0.24803471396071333 2.3048837891017876e-06 5.637350966597169 0.4277959938218786 SCS(ph)FSSESR ddPTM_PC-9_Lapatinib_30min_R1 2 SCSFSSESR 9 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 S(0.007)CS(0.762)FS(0.226)S(0.005)ESR;S(0.015)CS(0.93)FS(0.051)S(0.004)ESR 97.81299999999999 0.0046629 52032000.0 60307.0 120090.0 65962.0 46489.0 60092.0 59211.0 63520.0 63857.0 69152.0 43476.0 True False 59447.0111210507 119811.93898330789 60538.858980683384 49907.95614275779 56557.50670541757 56678.68355758249 66808.75479425295 66824.02934143976 61363.37355715729 50990.76867187144 1.165838693344587 2.3496790125739166 1.1872513507347666 0.9787645380268414 1.109171486889488 1.1115479337507759 1.310212741136953 1.3105122962835936 1.2034212300668414 1.0 15.637948465912437 -5.470869159162704 24.524012252048134 1.1568595687760452 1.7604365019533128 0.4208127245948773 0.28472753581325094 229.49359000720065 108212.01369316144 0.06904534637982009 0.1437267131192379 3.3816670107367083e-06 5.470869159162704 0.6035769331772676 SCS(ph)IDRSPGAGSLGSPASQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SCSIDRSPGAGSLGSPASQR 20 1 E9PC47;P53667-4;P53667-2;P53667 E9PC47 LIMK1 LIM domain kinase 1 1 S(0.155)CS(0.843)IDRS(0.002)PGAGSLGSPASQR 51.938 0.018690000000000002 12460000.0 12117.0 4128.0 9569.6 11336.0 12554.0 8860.1 8758.2 7442.7 8787.9 9848.8 True False 14168.168778341122 4537.800558998412 9797.775556910103 10700.880671807863 10094.13381964305 8395.460758685367 7928.5598921230485 7247.337011192497 8916.406412426575 11634.30947694209 1.21779198038533 0.39003608834644027 0.8421450002106448 0.9197692989872601 0.8676177851077885 0.7216122946810242 0.6814809170958168 0.6229279894570378 0.7663889661950203 1.0 13.506097965560912 -6.774527966641878 24.141944246894408 0.7301024277578989 0.8257794909942292 0.029432283326304987 0.21035265160804953 564.5347605725918 1041277.3052211034 0.07138821169306805 0.06337208973379418 1.68062969711223e-07 6.774527966641878 0.0956770632363303 SCS(ph)LGSLGALGPACCR ddPTM_PC-9_AZD4547_30min_R2 1 SCSLGSLGALGPACCR 16 0 Q15633-2;Q15633 Q15633-2 TARBP2 RISC-loading complex subunit TARBP2 1 S(0.005)CS(0.995)LGSLGALGPACCR 103.13 0.0014057 3167800.0 5822.6 6000.6 8351.0 10060.0 9583.3 6176.2 6645.1 7007.1 7855.0 7307.8 True False 7674.065682396347 7940.176601871403 8240.260283553527 7740.82242545064 8252.824214799126 5790.001237647913 7236.501026735552 5924.313702139431 8270.199263699675 7051.956146321201 1.0882180097503418 1.1259537690139438 1.1685070230977301 1.0976844246952386 1.170288646662158 0.8210489568441781 1.0261693176453774 0.8400950855643043 1.1727525089636293 1.0 12.783807787726074 -6.7355209369247815 24.999707438769757 0.9654037909560208 1.1302278654699918 0.4080992993230219 0.09504516531096731 207.57772049262337 200219.1467350612 0.029229363496279515 0.029220104165930533 1.838565316238571e-07 6.7355209369247815 0.16482407451397096 SCS(ph)LGSLGALGPACCR ddPTM_PC-9_Lapatinib_30min_R1 1 SCSLGSLGALGPACCR 16 0 Q15633-2;Q15633 Q15633-2 TARBP2 RISC-loading complex subunit TARBP2 1 S(0.014)CS(0.961)LGS(0.025)LGALGPACCR 83.869 0.0051489 2692100.0 7953.1 6865.3 8561.5 6570.1 9952.5 8449.6 7969.4 7560.0 8108.9 7602.0 True False 7839.687335580081 6849.403819652777 7857.606518345721 7053.287071211104 9367.11351736785 8088.2303049796365 8382.016537426322 7911.265199136883 7195.590291497469 8915.995570971721 0.8792834488505317 0.7682152559555708 0.8812932280864009 0.7910823883958471 1.0505964749315104 0.907159524766131 0.9401099934051219 0.8873114770148617 0.8070428292858884 1.0 13.122180184599959 -6.209947221370969 24.999986146423613 0.9255625081603787 0.8292236603360803 0.3419436777513909 0.06901364646447612 433.58675410467185 210510.6101029533 0.020152685404049516 0.0260169866003695 6.16669939531048e-07 6.209947221370969 -0.09633884782429836 SCS(ph)MNQLSSGIPVPKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SCSMNQLSSGIPVPKPR 17 1 A0A1X7SBY3;H0Y860;Q9P246;Q9P246-2 A0A1X7SBY3 STIM2 Stromal interaction molecule 2 1 S(0.154)CS(0.845)MNQLS(0.001)SGIPVPKPR 91.59200000000001 0.0035792000000000003 0.0 36412.0 48554.0 46626.0 34647.0 66288.0 41911.0 38742.0 41148.0 38262.0 31117.0 True False 42575.83243021847 53374.120237792886 47737.74067008969 32705.840917089565 53299.34225238952 39713.11337990118 35072.07729220971 40067.908599909795 38821.50936540763 36758.26577796355 1.1582655364482002 1.4520304238561355 1.2986940395514606 0.8897547320280981 1.44999610630005 1.0803859360445958 0.9541276376872844 1.0900380567989245 1.0561300579278414 1.0 15.165781082722892 -6.433560773271878 0.5363780604357337 1.007528227422944 1.3253443625399801 0.2643677793216612 0.16017160384193163 1.4844509278397588 0.8925338733849951 0.13224473990830013 0.2307920114309199 3.685014717587553e-07 6.433560773271878 0.3178161351170361 SCS(ph)PELQQK ddPTM_PC-9_Lapatinib_30min_R1 1 SCSPELQQK 9 0 P16152 P16152 CBR1 Carbonyl reductase [NADPH] 1 1 S(0.005)CS(0.995)PELQQK 90.913 0.008206399999999999 4508300.0 29599.0 35305.0 40043.0 34896.0 36523.0 37841.0 26047.0 27852.0 38945.0 33331.0 True False 29176.912832208163 35223.253441632725 36750.81911045 37462.36824964347 34374.78894698074 36222.62864167943 27395.586211050195 29146.10559872491 34558.60399096904 39092.21893923419 0.7463611333386166 0.9010297802840133 0.940105732232194 0.9583075421703691 0.8793256018650073 0.9265943357675523 0.7007938396547533 0.7455730677255814 0.8840276896199649 1.0 15.254593856266018 -7.199167376247517 24.99882903256102 0.8113945377798487 0.8969973437936042 0.0696160562796333 0.09323395477642595 415.97350968063233 166990.46699675682 0.03516706896619649 0.0272402884602746 6.321681680409082e-08 7.199167376247517 0.08560280601375547 SCS(ph)PLAFSAFGDLTIK ddPTM_PC-9_AZD4547_30min_R2 2 SCSPLAFSAFGDLTIK 16 0 E9PLZ8;Q96EY5;Q96EY5-2 E9PLZ8 MVB12A Multivesicular body subunit 12A 1 S(0.007)CS(0.993)PLAFSAFGDLTIK;S(0.002)CS(0.998)PLAFSAFGDLTIK 176.42 9.9529e-06 7935600.0 32783.0 30752.0 40514.0 62993.0 56594.0 41845.0 44119.0 50983.0 39523.0 42267.0 True False 43207.31207123958 40691.98261186371 39976.75788862264 48470.9370821483 48736.899983548625 39228.42553501781 48045.50553017199 43104.7488227904 41612.10509219631 40787.24519507352 1.0593339134474904 0.9976644026152245 0.9801289029799743 1.1883846739422073 1.1949054110042054 0.9617816880595801 1.1779541692601283 1.0568193222325495 1.020223476559344 1.0 15.315830449131019 -5.720793598519113 24.999974268902392 1.0913197412918836 1.010904570113672 0.15051648325736056 0.0790502238144539 271.5096256536558 166995.15667351 0.02147047949916042 0.03718743041580807 1.9019819953636933e-06 5.720793598519113 -0.08041517117821151 SCS(ph)PLAFSAFGDLTIK ddPTM_PC-9_Lapatinib_30min_R1 2 SCSPLAFSAFGDLTIK 16 0 E9PLZ8;Q96EY5;Q96EY5-2 E9PLZ8 MVB12A Multivesicular body subunit 12A 1 SCS(1)PLAFSAFGDLTIK;S(0.076)CS(0.923)PLAFS(0.001)AFGDLTIK 233.47 6.9868e-37 14916200.0 52818.0 64886.0 63924.0 73667.0 71853.0 81622.0 73203.0 67889.0 83048.0 59954.0 True False 52064.80563436506 64735.76045358397 58668.4154737758 79084.71692590814 67626.74780843331 78131.2173301751 76993.09315497003 71043.37078097915 73694.25970579016 70316.96901631658 0.7404301744331979 0.9206278563935609 0.834342212050724 1.1246889340118893 0.9617415078391814 1.1111289127386204 1.0949432865501398 1.0103303907267962 1.048029525969612 1.0 16.10158526460171 -5.74997596254155 24.99963277695948 1.051280488910051 0.8406827724600382 0.7155482825320515 0.06300277459255377 114.31913452119025 249307.05828241652 0.016351014698621637 0.028005902457153203 1.7783778374935076e-06 5.74997596254155 -0.2105977164500129 SCS(ph)SPAVSAVSQLPLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 SCSSPAVSAVSQLPLSPK 18 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 2 S(0.063)CS(0.467)S(0.467)PAVS(0.002)AVSQLPLS(1)PK 103.4 0.0049001 6263300.0 42177.0 42131.0 35081.0 40201.0 43261.0 39174.0 33277.0 38525.0 37427.0 32503.0 True False 41575.54824568549 42033.44825802092 32196.775596576077 43157.5156466047 40716.47303439843 37498.6193390542 34999.9202343885 40315.01214242701 33211.577136217704 38121.10024247484 1.0906177413883158 1.1026294621787154 0.8445919816527795 1.1321162131233098 1.068082315972397 0.9836709617649739 0.9181246084652956 1.0575511169928853 0.8712124499285332 1.0 15.218302138132447 -6.889642416028944 5.551148005865901 0.9645385278089367 1.0437363427757316 0.18418529076204393 0.08634371832212995 0.4051943168452085 18.262523185504374 0.030608644314588825 0.026973566452423485 1.2893106913272659e-07 6.889642416028944 0.0791978149667949 SCS(ph)SPAVSAVSQLPLSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SCSSPAVSAVSQLPLSPK 18 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 S(0.001)CS(0.791)S(0.209)PAVSAVSQLPLSPK 225.01 7.2289e-35 4919500.0 48669.0 42344.0 40284.0 48790.0 54069.0 38604.0 37988.0 33860.0 41399.0 31002.0 True False 56907.700443433554 46547.632478253116 41244.52333792078 46056.454479314234 43474.56758756415 36579.53828154198 34389.501630696956 32971.21087763551 42004.38205578672 36622.41718830305 1.5539034507424454 1.2710147513998642 1.126209750870677 1.2576028021990955 1.18710262525898 0.9988291622985834 0.9390287225956436 0.9003013293225847 1.146958209771108 1.0 15.160439395984815 -1.5228787452803987 0.3691537001633272 0.9805816676180058 8.178672171713405 0.7546261691414947 0.09162093810803576 33.86597143089041 0.46831266952559836 0.07800723200142906 172.72421001737868 0.029999999999995777 1.5228787452803987 7.198090504095399 SCSPSPVS(ph)PQVQPQAADTISDSVAVPASLLGMR ddPTM_PC-9_Lapatinib_30min_R1 1 SCSPSPVSPQVQPQAADTISDSVAVPASLLGMR 33 0 Q9NQW6;Q9NQW6-2;C9JJT6 Q9NQW6 ANLN Actin-binding protein anillin 1 S(0.138)CS(0.138)PS(0.334)PVS(0.387)PQVQPQAADT(0.003)IS(0.001)DSVAVPASLLGMR 47.674 0.007459100000000001 3055100.0 5327.2 5848.3 7399.1 7006.6 7294.0 6302.8 4561.7 6382.2 8546.4 4963.1 True False 5251.233151111165 5834.758620668482 6790.774559351962 7521.888737332412 6864.981260555751 6033.243936544412 4797.882505430477 6678.740311366586 7583.814434418227 5820.965222084946 0.902124123880315 1.002369606767483 1.166606275809298 1.2922064383401748 1.1793544538815954 1.0364679578661753 0.824241740395071 1.1473595970007193 1.3028448281472238 1.0 12.507042682753763 -5.016127618315667 3.6379565876823423 1.1182591171750398 0.9121198003364941 0.21433031299064254 0.13374863753662716 0.37876933230340676 10.57078359338802 0.037699307205094096 0.1540897888199485 9.63545842116371e-06 5.016127618315667 -0.2061393168385457 SCSS(ph)PAVSAVSQLPLSPK ddPTM_PC-9_AZD4547_30min_R2 1 SCSSPAVSAVSQLPLSPK 18 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 S(0.005)CS(0.179)S(0.816)PAVSAVSQLPLSPK 130.64 4.1221000000000004e-05 8411400.0 48335.0 46895.0 51255.0 75320.0 74911.0 71739.0 50495.0 76027.0 49774.0 62548.0 True False 63704.52456954411 62052.8916682931 50575.32521057794 57956.13768239979 64510.90070798339 67253.14898928526 54988.95717822331 64278.77407665864 52404.952024365026 60358.2135581295 1.0554408557534902 1.028077009080653 0.8379195179769543 0.9602029991590734 1.0688006967909105 1.1142335901727014 0.9110434841691397 1.0649548799974564 0.8682323239055959 1.0 15.881262486126976 -3.1134182106281925 19.59113920547894 0.9919985624545754 86.34571552496868 0.0 0.08841736950352774 0.0 0.0 0.020341191484253566 0.0 0.0007701614728907359 3.1134182106281925 85.35371696251411 SCSS(ph)PAVSAVSQLPLSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SCSSPAVSAVSQLPLSPK 18 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 S(0.033)CS(0.209)S(0.758)PAVSAVSQLPLSPK 152.68 3.2899e-05 5031800.0 46278.0 35358.0 40527.0 48321.0 52431.0 41403.0 44631.0 33362.0 36927.0 34404.0 True False 54111.95136783616 38868.10856711867 41493.3173795034 45613.73102879568 42157.52192908275 39231.753794184086 40403.228579541865 32486.282849960888 37466.987515979505 40641.17285808586 1.331456440905105 0.9563727086036979 1.0209675179501616 1.1223527231380206 1.03731066217729 0.9653204136400467 0.9941452408527955 0.7993441272819345 0.921897299736151 1.0 15.310654416800478 -6.830191409108239 1.06993971860373 0.9023745638330156 1.1000030519062058 0.38068381442553223 0.10379108979205695 0.5461152989706718 1.3244058590264662 0.05806721022502538 0.04908862421807451 1.478456635845497e-07 6.830191409108239 0.19762848807319022 SCSS(ph)PAVSAVSQLPLSPK ddPTM_PC-9_Lapatinib_30min_R1 2 SCSSPAVSAVSQLPLSPK 18 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 S(0.004)CS(0.046)S(0.949)PAVSAVSQLPLSPK;S(0.006)CS(0.181)S(0.804)PAVS(0.009)AVS(0.001)QLPLSPK 271.27 7.013999999999999e-79 11064200.0 124166.0 98020.0 93595.0 80629.0 102477.0 100990.0 82276.0 80991.0 98659.0 67210.0 True False 122395.3700707444 97793.0407123308 85899.98038714797 86558.72563045936 96449.50433753377 96670.89311918842 86535.84870044021 84754.137532182 87546.98449467238 78827.15894830438 1.5527055865480637 1.2406008540338798 1.0897256926826706 1.0980825236543843 1.2235567743953109 1.2263653087203883 1.0977923073085922 1.0751895496800106 1.1106195588259948 1.0 16.266405158081383 -4.786293253477856 2.6174289379291356 1.1249273190636448 1.638451968349968 0.8076385106818147 0.06441712584976793 0.2109476421774751 1.907914748925043 0.01750593595707516 0.24137634842891384 1.635711648731048e-05 4.786293253477856 0.5135246492863232 SCSSISTALPQVNEDLVSLPHQLPEASEPPQS(ph)PSEKR ddPTM_PC-9_Lapatinib_30min_R1 1 SCSSISTALPQVNEDLVSLPHQLPEASEPPQSPSEKR 37 1 A0A075B784;Q9P275 A0A075B784 USP36 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 36 1 SCSSISTALPQVNEDLVSLPHQLPEAS(0.003)EPPQS(0.699)PS(0.298)EKR 75.851 1.9579e-09 7875600.0 26678.0 20018.0 24378.0 16946.0 26236.0 25911.0 16150.0 17239.0 23977.0 20157.0 True False 26297.56682785397 19971.649550902253 22373.73494180132 18192.26537019882 24692.850061960584 24802.846931491127 16986.167977443103 18039.98687406358 21276.457770996654 23641.11059248579 1.1123659662677827 0.8447847436257983 0.9463910273704611 0.7695182211947835 1.044487735267779 1.0491405145481867 0.7185012696840931 0.7630769630508601 0.8999770838921277 1.0 14.529010190387933 -7.259137686537314 24.999671593574917 0.8256452456158121 0.9502384678100123 0.17578796675466934 0.1183488075225526 344.08511707544176 3737280.026909959 0.046652228787316015 0.0343655551412313 5.5063309878305844e-08 7.259137686537314 0.12459322219420021 SCSSPAVSAVSQLPLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 SCSSPAVSAVSQLPLSPK 18 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 SCSSPAVSAVSQLPLS(1)PK;SCSSPAVSAVSQLPLS(1)PK 239.8 1.1102e-43 37743000.0 201999.0 158465.0 172075.0 224877.0 203537.0 179950.0 188009.0 186177.0 171972.0 187415.0 True False 266230.4801597876 209685.71229802896 169793.17306819244 173035.08196501632 175279.40085435825 168697.69805296825 204741.436778306 157407.6225718507 181062.0888322039 180853.65789468598 1.4720768341595718 1.1594220141244385 0.9388429022932219 0.9567684943689525 0.9691780796406467 0.932785656739128 1.1320834710323098 0.8703590759746297 1.0011524839472106 1.0 17.464463252265475 -4.844945626931915 2.3393424780888386 0.973865358932663 1.5541560752936843 0.8478921166546998 0.06466206683298704 0.1698356494490214 1.2698894303333423 0.016531358978491336 0.19383032674351816 1.4290728652563698e-05 4.844945626931915 0.5802907163610213 SCSSPAVSAVSQLPLS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SCSSPAVSAVSQLPLSPK 18 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 SCSSPAVSAVSQLPLS(1)PK;SCSSPAVSAVSQLPLS(1)PK 220.1 6.8625e-28 27323000.0 189269.0 176662.0 157892.0 211387.0 209738.0 195057.0 235990.0 218117.0 202981.0 163884.0 True False 221308.5034668524 194199.83584151627 161656.74408874448 199543.671715901 168641.34451683093 184827.86754177627 213635.31878035676 212391.65986406477 205949.21312267543 193594.87189497004 1.1431527152584788 1.0031248965461979 0.8350259617230317 1.0307280857323449 0.8711043989239704 0.9547146870814321 1.1035174469717315 1.0970934187724375 1.0638154363634587 1.0 17.562681212226586 -7.255522647395873 24.615989320323347 1.0741976949404755 0.9660697951567606 0.22396639057820378 0.0838027094383663 538.6936661645406 2241188.4285821933 0.03313647297921029 0.02495839295718377 5.552356621817452e-08 7.255522647395873 -0.10812789978371484 SCSSPAVSAVSQLPLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 SCSSPAVSAVSQLPLSPK 18 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 SCSSPAVSAVSQLPLS(1)PK;SCSSPAVSAVSQLPLS(1)PK 159.18 8.4079e-06 29595000.0 135343.0 103478.0 96497.0 113251.0 108106.0 101767.0 104975.0 104117.0 102000.0 88865.0 True False 133412.98400113333 103238.40304866947 88563.38914919183 121579.85633426109 101747.41762457351 97414.66264046376 110410.0918533802 108954.65591779583 90511.68589238265 104225.19684483038 1.280045402070648 0.9905320994727403 0.8497310806814237 1.1665111701853457 0.9762266774708446 0.9346555879908187 1.059341648620322 1.045377310056863 0.8684242259300858 1.0 16.669344571330463 -4.761410407890242 23.32500760890872 0.9907575658378271 1.280045793268099 0.49961588471706575 0.08767804188885453 0.255555501005358 196619.1746098629 0.021256862489768068 0.11854994533968591 1.7321663284736792e-05 4.761410407890242 0.28928822743027194 SCT(ph)PSPDQISHR ddPTM_PC-9_AZD4547_30min_R2 3 SCTPSPDQISHR 12 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 S(0.191)CT(0.802)PS(0.008)PDQISHR;S(0.12)CT(0.631)PS(0.25)PDQISHR;S(0.022)CT(0.871)PS(0.108)PDQISHR 82.529 0.025193 20482600.0 24443.0 22158.2 47782.0 57160.0 43926.0 48619.0 36882.6 53842.0 42802.0 46235.0 True False 32215.365554016054 29320.404822782213 47148.37945979583 43982.64511319664 37827.63311795166 45578.8462441637 40165.07994893632 45521.95606607458 45064.426337985176 44616.32672283873 0.7220532912568366 0.6571676105234665 1.056751707792676 0.9857970914195024 0.8478428390786372 1.0215732578637469 0.9002327824620342 1.02029816010766 1.010043399985169 1.0 15.44528412045356 -5.255393194490867 24.999569192897717 0.9751200674033285 0.6896104196083147 0.786127705995235 0.06060365007439091 205.9807643390235 851676.6442362145 0.015455353443915748 0.03873575141469372 5.554011894584874e-06 5.255393194490867 -0.28550964779501375 SCT(ph)PSPDQISHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SCTPSPDQISHR 12 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 S(0.15)CT(0.596)PS(0.254)PDQISHR;S(0.181)CT(0.74)PS(0.078)PDQISHR 153.2 0.00044133 22134000.0 14249.2 22796.0 29925.0 28123.0 37002.0 30769.0 26913.0 22286.2 22935.4 16819.6 True False 16661.308125471518 25059.03622648444 30638.525491194476 26547.35948599618 29751.723721079514 29155.419474271177 24363.605806753378 21701.21086418078 23270.786835486142 19868.860336119647 0.8385638553804159 1.2612216202924111 1.5420373877960494 1.3361289493658413 1.497404643133647 1.4673926426101789 1.2262205981921732 1.0922222259889813 1.1712190051073097 1.0 14.278221502535509 -7.565533585030671 4.09994872768511 1.1017566049103833 1.3403169856113417 0.23422626515036693 0.18855739896840037 0.3362528379124385 12.242490267012297 0.09774570354915876 0.05536190076717808 2.7193581834971867e-08 7.565533585030671 0.23856038070095842 SCT(ph)PSPDQISHR ddPTM_PC-9_Lapatinib_30min_R1 2 SCTPSPDQISHR 12 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 S(0.156)CT(0.81)PS(0.034)PDQISHR;S(0.157)CT(0.693)PS(0.15)PDQISHR 153.41 0.00044939 22016400.0 38538.0 36600.0 48239.0 28985.0 31707.0 31143.0 32796.0 34477.0 41687.0 30740.0 True False 37988.44105299635 36515.25494869732 44272.97562792491 31116.653591125516 29842.056598360436 29811.0864878788 34494.016407939576 36078.927284476464 36991.771076429 36053.368041524685 1.0536724615920192 1.0128111999589235 1.227984458398817 0.8630720313088841 0.8277189682802912 0.82685996086534 0.9567487944041978 1.0007089280236547 1.0260281656300045 1.0 15.137846419316126 -5.7794081458280875 24.99999955314948 0.9214769571844765 1.0896216179858482 0.4528896406345081 0.08491715889880103 227.0627857656322 315912.36850056716 0.0259094250077417 0.03851689817620064 1.6618501253026764e-06 5.7794081458280875 0.1681446608013717 SCTPS(ph)PDQISHR ddPTM_PC-9_AZD4547_30min_R2 3 SCTPSPDQISHR 12 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 SCT(0.059)PS(0.936)PDQIS(0.004)HR;S(0.002)CT(0.02)PS(0.979)PDQISHR;SCT(0.1)PS(0.899)PDQIS(0.001)HR 147.56 0.0001375 41805400.0 79110.0 80630.0 104453.0 136414.0 120454.0 98514.0 75001.0 106946.0 80167.0 85407.0 True False 104265.33440977854 106692.07069441256 103067.88497162223 104965.85987529064 103731.04128738672 92353.90400661364 81675.94370381092 90419.9530745961 84404.46395582576 82416.92692586775 1.265096119193609 1.2945407536291638 1.2505669504558157 1.2735958957764242 1.258613311082207 1.120569614172632 0.9910093320669026 1.0971041562363384 1.0241156410957395 1.0 16.33065305050266 -6.8842808690191175 2.8876116243717096 1.0365008089968006 1.271354422463814 0.9371265671008209 0.029461184912781293 0.05848347193459864 0.9828087095537833 0.010835251547111286 0.009387775161127432 1.3053264280999545e-07 6.8842808690191175 0.2348536134670134 SCTPS(ph)PDQISHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SCTPSPDQISHR 12 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 S(0.01)CT(0.029)PS(0.962)PDQISHR;SCT(0.312)PS(0.688)PDQISHR;S(0.068)CT(0.292)PS(0.64)PDQISHR;S(0.014)CT(0.011)PS(0.975)PDQISHR;S(0.001)CT(0.296)PS(0.703)PDQISHR 150.22 0.00017183 44776400.0 120125.0 114572.0 140404.0 140698.0 161689.0 138034.0 146944.0 139407.0 136656.0 111568.0 True False 140459.7899231024 125945.95098003084 143751.76384513508 132815.1472090705 130007.20114419826 130795.25404503061 133024.40053756785 135747.71396392598 138654.3354722477 131794.3952281978 1.0657493414640338 0.9556244843489697 1.0907274440330599 1.0077450333081714 0.9864395289275765 0.992418940263452 1.0093327588570087 1.0299961066544836 1.0520503184689467 1.0 17.007929493125594 -10.908701727172364 2.8585244910176475 0.9996697049107383 1.0188981222149907 0.02394821057977148 0.03814560258032051 13651878.34136363 16359527.279752318 37417.07448333053 0.009184826601266804 1.2339520187503891e-11 10.908701727172364 0.0192284173042524 SCTPS(ph)PDQISHR ddPTM_PC-9_Lapatinib_30min_R1 4 SCTPSPDQISHR 12 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 S(0.011)CT(0.231)PS(0.759)PDQISHR;SCT(0.151)PS(0.849)PDQISHR;SCTPS(1)PDQISHR;S(0.011)CT(0.007)PS(0.982)PDQISHR 162.88 3.1817e-05 65718500.0 185093.0 169410.0 234871.0 187275.0 180238.0 217406.0 174673.0 173660.0 218356.0 175318.0 True False 182453.53987810074 169017.7415535196 215560.8130082788 201047.82823108573 169636.75520154176 208108.0521781389 183716.71325844698 181728.87757699893 193762.44788938362 205621.48270344935 0.8873272261208145 0.8219848399657721 1.0483379954961425 0.9777569230012809 0.8249952921806066 1.0120929459412358 0.8934704236298413 0.8838029722754761 0.9423258958249561 1.0 17.649631475207165 -5.78022763059133 0.008432650774979168 1.8341678214322492 2.0289171692147564e-06 0.07980422085393613 0.07181860889726525 21714.8902641877 41.33812248483153 4308.467562430539 4685.6285425849655 1.6587172814592043e-06 5.78022763059133 -1.83416579251508 SCTPSPDQIS(ph)HRASLEDAPVDDLTR ddPTM_PC-9_AZD4547_30min_R2 1 SCTPSPDQISHRASLEDAPVDDLTR 25 1 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 S(0.001)CT(0.001)PS(0.002)PDQIS(0.498)HRAS(0.498)LEDAPVDDLT(0.001)R 58.92 0.0017280999999999998 29135000.0 28934.0 27268.0 38781.0 61539.0 57276.0 44215.0 31307.0 40040.0 36400.0 38244.0 True False 38134.41013541305 36081.84774519708 38266.73860094476 47352.13431807226 49324.21605572551 41450.22906036115 34093.26235030474 33852.738027666644 38324.0296879272 36905.08920056762 1.0333103363648426 0.9776930100101783 1.0368959791148857 1.283078712009832 1.3365152916353573 1.1231575362165394 0.9238092384770707 0.9172918630188805 1.038448368994533 1.0 15.171532156760774 -7.230791819561524 9.172069105152469 0.9630161536848475 1.136787287752079 0.3461958996384823 0.10869918518306328 0.5230868823752441 151.41051034942677 0.04838725581752539 0.03709705261482616 5.877710349230526e-08 7.230791819561524 0.17377113406723155 SCTPSPDQIS(ph)HRASLEDAPVDDLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SCTPSPDQISHRASLEDAPVDDLTR 25 1 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 S(0.002)CT(0.005)PS(0.021)PDQIS(0.527)HRAS(0.445)LEDAPVDDLT(0.001)R 48.115 0.014542 17172000.0 9374.0 8432.9 10193.0 16595.0 20712.0 18363.0 22119.0 20217.0 17322.0 15667.0 True False 10960.833055060642 9270.062580905458 10436.039777167767 15665.235951715913 16653.63228233606 17400.01195378602 20023.728192307724 19686.32517168214 17575.30147999559 18507.303080096233 0.592243667682112 0.5008867332418082 0.5638876573211391 0.8464353711569766 0.8998411173287743 0.9401700441432196 1.0819365796112312 1.0637057753084451 0.949641414739516 1.0 14.175807057769989 -5.978482052721881 1.3385162756606221 1.014377371317122 0.5201438108832482 0.9261404547596742 0.055185208307691115 0.10726326496189534 0.39006615990680793 0.020571026937744742 0.03868214196479671 1.050794878208567e-06 5.978482052721881 -0.4942335604338738 SCTPSPDQIS(ph)HRASLEDAPVDDLTR ddPTM_PC-9_Lapatinib_30min_R1 3 SCTPSPDQISHRASLEDAPVDDLTR 25 1 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 S(0.001)CT(0.001)PS(0.005)PDQIS(0.497)HRAS(0.497)LEDAPVDDLTR;S(0.005)CT(0.014)PS(0.132)PDQIS(0.601)HRAS(0.247)LEDAPVDDLTR;SCTPS(0.012)PDQIS(0.961)HRAS(0.027)LEDAPVDDLTR 77.57600000000001 5.3636999999999995e-05 30015100.0 45644.1 31782.4 45401.0 31020.1 41389.4 42782.6 39523.3 33407.6 51947.4 32431.1 True False 44993.20676389723 31708.80980550484 41668.30503292809 33301.421634020095 38954.95686669127 40952.88792911163 41569.62308500786 34959.839056439865 46096.53678162708 38036.77242327559 1.1828870826160012 0.8336356579534986 1.0954742576273446 0.8755059778321825 1.0241393889365287 1.0766656926982479 1.0928798748331872 0.9191063497029817 1.2118940132107405 1.0 15.215107212328196 -6.520316811121693 24.27723475017426 1.0563571900344813 0.9869540223967447 0.05947844935416935 0.11577804811517416 194.16872570881512 1840005.0174502905 0.0350606917816828 0.03568637789408017 3.01774951556648e-07 6.520316811121693 -0.06940316763773657 SCTPSPDQISHRAS(ph)LEDAPVDDLTR ddPTM_PC-9_AZD4547_30min_R2 2 SCTPSPDQISHRASLEDAPVDDLTR 25 1 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 SCT(0.002)PS(0.051)PDQIS(0.204)HRAS(0.742)LEDAPVDDLTR;S(0.001)CT(0.001)PS(0.003)PDQIS(0.021)HRAS(0.974)LEDAPVDDLT(0.001)R 66.711 0.00035671 31771400.0 16738.2 14463.2 29637.1 42675.0 31849.0 25547.2 18208.0 28878.4 21046.5 25165.4 True False 22060.599423811815 19138.146556708743 29244.092689462854 32836.93807217753 27427.3161037573 23949.72954542257 19828.47672643014 24415.906839614578 22158.97502271867 24284.36700575162 0.9084280194985885 0.7880850487960414 1.2042353289479009 1.3521842288250823 1.1294227309800289 0.9862200459970897 0.8165119857451452 1.005416646595392 0.9124790041869503 1.0 14.567740261234746 -6.951200880180151 5.969465131376277 0.9295233807391801 1.081655418962697 0.16549113339689958 0.15184026597600236 0.3871683368909224 31.610766602822622 0.06151846272235572 0.0537387292018145 1.1189202142488776e-07 6.951200880180151 0.15213203822351695 SCTPSPDQISHRAS(ph)LEDAPVDDLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SCTPSPDQISHRASLEDAPVDDLTR 25 1 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 SCTPS(0.004)PDQIS(0.246)HRAS(0.749)LEDAPVDDLTR 70.959 0.0002019 16341000.0 7368.0 6393.2 10902.0 12396.0 13310.0 14917.0 13959.0 15973.0 11853.0 8558.3 True False 8615.256875366635 7027.874644813142 11161.945026065241 11701.492308374238 10702.001046634463 14134.726260122301 12636.702465591747 15553.72567479244 12026.327701327076 10109.852042534481 0.8521644865938948 0.6951510877948808 1.1040661108693146 1.1574345756142976 1.058571480730744 1.3981140575207476 1.249939406870271 1.538472136818059 1.1895651539438499 1.0 13.303474263134222 -5.54153147806918 0.9684771613657381 1.29047223897121 0.7086573882158133 0.5471206490594123 0.15725782086923507 0.5462878532699023 0.8429067528897016 0.058194472602254244 0.2599810043136129 2.8738792846144516e-06 5.54153147806918 -0.5818148507553967 SCTPSPDQISHRAS(ph)LEDAPVDDLTR ddPTM_PC-9_Lapatinib_30min_R1 3 SCTPSPDQISHRASLEDAPVDDLTR 25 1 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 SCTPS(0.001)PDQIS(0.047)HRAS(0.951)LEDAPVDDLTR;SCTPSPDQIS(0.14)HRAS(0.86)LEDAPVDDLTR;SCT(0.001)PS(0.018)PDQIS(0.314)HRAS(0.667)LEDAPVDDLTR 80.683 2.978e-05 44897700.0 40742.3 33529.5 50353.1 32985.9 45462.5 47922.1 37175.1 38461.6 49930.6 31192.1 True False 40161.30733077724 33451.864502796336 46213.262486586915 35411.793123736665 42788.48513271395 45872.58349487133 39099.844778838706 40248.66634697392 44306.89003547257 36583.6129241393 1.0977949994730356 0.9143947748453102 1.2632230332858567 0.9679687240614384 1.16960796686323 1.2539106946597613 1.0687802995269255 1.1001829269961545 1.2111130228539333 1.0 15.158909939336732 -5.2496954555561075 24.99417238338064 1.1308860966123286 1.0060949048219143 0.1865929305789611 0.10289545856384637 1166.6858411175413 2483003.8406959358 0.02484686190812495 0.06456277491350991 5.62735799432472e-06 5.2496954555561075 -0.12479119179041431 SCTVNIMFGT(ph)PQEHR ddPTM_PC-9_AZD4547_30min_R2 1 SCTVNIMFGTPQEHR 15 0 Q9HCD5 Q9HCD5 NCOA5 Nuclear receptor coactivator 5 1 SCTVNIMFGT(1)PQEHR 83.395 0.006809100000000001 4964500.0 27470.0 20119.0 35439.0 50689.0 47398.0 32263.0 28357.0 31834.0 25938.0 37575.0 True False 36204.88858850472 26622.073301511653 34969.05570456875 39003.43418724326 40817.605849034146 30245.589509768914 30880.718065211986 26914.786772545936 27309.02972652351 36259.51068693988 0.9984935787218211 0.7342093921609515 0.964410579240499 1.0756745871171312 1.125707575081426 0.8341422412151555 0.8516584333371808 0.7422821285406984 0.7531549436037978 1.0 15.146071835952855 -6.961382975901736 24.97670863040181 0.8192405490658206 0.9714817115751081 0.2687454940898264 0.116505095077714 222.0891577354573 143642.12931477439 0.0436835553598855 0.03852520348090997 1.0929921029177773e-07 6.961382975901736 0.15224116250928754 SCTVNIMFGT(ph)PQEHR ddPTM_PC-9_Lapatinib_30min_R1 1 SCTVNIMFGTPQEHR 15 0 Q9HCD5 Q9HCD5 NCOA5 Nuclear receptor coactivator 5 1 SCTVNIMFGT(1)PQEHR 69.03 0.026563999999999997 4102200.0 32227.0 22801.0 24583.0 22115.0 19033.0 27710.0 28930.0 23700.0 25468.0 20327.0 True False 31767.437070291995 22748.205685389254 22561.8806331242 23741.41087347735 17913.516360317728 26524.907895164954 30427.85384442285 24801.188521103708 22599.52565007062 23840.494865975048 1.3324990629968094 0.9541834518651414 0.9463679659319625 0.9958438785329449 0.7513902903871239 1.1125988803622142 1.276309657810385 1.0402967161768002 0.9479470026574185 1.0 14.541126562215224 SCWPSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 SCWPSSPR 8 0 D6RC00 D6RC00 IRX4 1 S(0.042)CWPS(0.083)S(0.875)PR 69.598 0.040429 2130600.0 16603.0 13942.0 10636.0 10424.0 8325.6 8598.0 10108.0 11652.0 17684.0 20883.0 True False 21882.408636146498 18448.478849330248 10494.959690561058 8020.907849194576 7169.734150316862 8060.365700802563 11007.592418209359 9851.451136322961 18618.740137398465 20151.892526290503 1.0858736273825564 0.9154712801917759 0.5207927581426486 0.3980225598528953 0.3557846560050429 0.3999805819868716 0.5462311990721798 0.48885984894324885 0.923920178370748 1.0 14.298627712599606 -10.738889723487857 13.137214652870021 0.9999880185980456 0.60382215557591 0.16803616031947588 0.24511546986213156 1.7879940874416026e-10 0.0 0.25771241622256436 0.06250444194816325 1.8243588866405126e-11 10.738889723487857 -0.39616586302213563 SCWPSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SCWPSSPR 8 0 D6RC00 D6RC00 IRX4 1 S(0.064)CWPS(0.029)S(0.907)PR 75.043 0.026929 2763000.0 17571.0 29961.0 31529.0 15015.0 59646.0 54362.0 21862.0 34155.0 51544.0 67533.0 True False 20545.423256930928 32935.33007464908 32280.770934398366 14173.758229286803 47958.79447239362 51511.16102116836 19791.0730928266 33258.46744021384 52297.73348833233 79776.19830906604 0.2575382594359109 0.4128465729471367 0.4046416301932236 0.177669010678791 0.6011667074757487 0.6456958605824471 0.2480824295004977 0.4168971215119214 0.6555555992493194 1.0 16.28367075377247 -14.522878745041824 0.16722012169069506 3.278308565311001 0.2785399321177386 0.63135873526255 0.1426712752990759 91.49744824938443 0.8545169198604807 68.73701833219886 0.5613944341447614 3.000000001647592e-15 14.522878745041824 -2.9997686331932627 SDAEEDGGTVS(ph)QEEEDRKPK ddPTM_PC-9_AZD4547_30min_R2 2 SDAEEDGGTVSQEEEDRKPK 20 2 P27824;P27824-2;P27824-3 P27824 CANX Calnexin 1 SDAEEDGGT(0.019)VS(0.981)QEEEDRKPK;SDAEEDGGT(0.005)VS(0.995)QEEEDRKPK 72.058 0.0011075999999999998 28678900.0 112427.0 115191.0 142168.0 91746.0 108026.0 84154.0 139431.0 106968.0 117369.0 94036.0 True False 148176.44737312818 152424.2380672213 140282.75942907896 70595.37716157004 93028.45456449137 78891.83707668495 151840.0888863624 90438.55348010588 123572.88572643753 90743.82826233076 1.6329093692715477 1.6797201637402714 1.5459206660703846 0.777963399973454 1.0251766576957277 0.8693906636671427 1.6732828203743935 0.9966358617652502 1.361777303126351 1.0 16.469511904331526 -5.6103229432348645 7.4148277167358145 1.1124200849060497 1.6455427904755018 0.49515204179056305 0.2414784202381043 0.18825675973299952 13.537449074666718 0.06636094465657828 0.11547789684931398 2.452884262127073e-06 5.6103229432348645 0.5331227055694521 SDAEEDGGTVS(ph)QEEEDRKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SDAEEDGGTVSQEEEDRKPK 20 2 P27824;P27824-2;P27824-3 P27824 CANX Calnexin 1 SDAEEDGGT(0.012)VS(0.988)QEEEDRKPK;S(0.001)DAEEDGGT(0.097)VS(0.902)QEEEDRKPK 46.131 0.024938 16073700.0 60047.0 69891.0 46969.0 45486.0 71247.0 33300.0 56447.0 33289.0 38636.0 37822.0 True False 70211.77111769012 76829.31658647221 48088.91909092443 42937.56688760171 57286.66180086885 31553.689378700325 51099.931519109996 32415.199022611007 39200.97840786914 44678.82920121276 1.5714774172234642 1.7195910895620954 1.0763245132130523 0.9610271275066495 1.2821880703918238 0.7062335773526455 1.1437168885733233 0.7255158562152101 0.8773949342165186 1.0 15.447303760363171 -5.338868146681817 4.142006891585777 0.9603318510113376 1.6486950531853926 0.7233966022899163 0.16760639545355008 0.10526908695141421 3.382029623387524 0.04392907215483219 0.1005988533381529 4.5828100130469224e-06 5.338868146681817 0.688363202174055 SDAEEDGGTVS(ph)QEEEDRKPK ddPTM_PC-9_Lapatinib_30min_R1 2 SDAEEDGGTVSQEEEDRKPK 20 2 P27824;P27824-2;P27824-3 P27824 CANX Calnexin 1 SDAEEDGGT(0.055)VS(0.945)QEEEDRKPK;SDAEEDGGT(0.231)VS(0.768)QEEEDRKPK 58.516000000000005 0.0054533 28362000.0 43285.0 85380.0 42145.0 26193.0 30677.0 30917.0 43521.0 38505.0 49655.0 15995.9 True False 42667.74796250319 85182.30785573141 38680.00078440461 28119.320597286547 28872.639173302538 29594.751981047066 45774.304430111544 40294.08286941345 44062.33100966926 18760.770001803012 2.2743068625862684 4.540448384983395 2.0617491062833375 1.4988361668835621 1.538990093185286 1.5774806672755355 2.4398947604875696 2.1477840656615355 2.3486419270336256 1.0 14.19543142142115 -5.422646679070455 7.999345245834591 1.8432032740991484 3.4003254013771222 0.48648243036047645 0.6531732637649469 0.22732746555170358 16.251697082977095 0.16364323319127813 0.3418056652584055 3.7787949033474457e-06 5.422646679070455 1.5571221272779738 SDAEEVDFAGWLCSTIGLNQPST(ph)PTHAAGV ddPTM_PC-9_Lapatinib_30min_R1 1 SDAEEVDFAGWLCSTIGLNQPSTPTHAAGV 30 0 H3BRW9;Q02750-2;Q02750 H3BRW9 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 1 SDAEEVDFAGWLCSTIGLNQPS(0.165)T(0.669)PT(0.165)HAAGV 87.35700000000001 1.9509e-08 778330.0 978.44 1052.2 1072.9 0.0 2083.9 2197.6 2454.1 891.53 927.4 952.64 True False 964.4872661760788 1049.7636955469748 984.6903035137677 0.0 1961.329099105035 2103.61377085581 2581.1612899964784 932.9537384902782 822.9464460450558 1117.30255468699 0.8632283727716686 0.9395518618867419 0.8813103481980551 0.0 1.7554144943797225 1.8827610856444634 2.310172190306667 0.8350054643450119 0.7365475381693748 1.0 10.125804191201304 -6.283155550492118 24.98642026442149 1.4793820680093155 0.7052237489955387 0.32565898110559044 0.5228933882119207 1007.1606447167901 1158826.311940407 0.1752157526572905 0.19884452256961846 5.210080691370426e-07 6.283155550492118 -0.7741583190137767 SDAGLES(ph)DTAMK ddPTM_PC-9_AZD4547_30min_R2 2 SDAGLESDTAMK 12 0 Q9NR30 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 SDAGLES(0.639)DT(0.361)AMK;SDAGLES(0.761)DT(0.239)AMK 109.44 0.0011551999999999999 36049000.0 132089.0 134356.0 163238.0 169944.0 146479.0 140224.0 129013.0 145574.0 133386.0 156117.0 True False 174090.55437812212 177783.94952522012 161073.35746218573 130766.0364086265 126142.91926158624 131455.77111297284 140494.9070687024 123078.88325773111 140436.51164708403 150651.39134831683 1.1555854401345174 1.1801016103075401 1.069179355202718 0.8680041733321004 0.8373166562394021 0.8725825227132331 0.932582871032821 0.8169780720654872 0.9321952515020903 1.0 17.200854471511555 -5.6132564756487495 3.3064511342335177 0.8846230767590552 1.162967150552476 0.8284587666745565 0.051220362579459285 0.0829958559169529 1.7924230722704821 0.013777880453366627 0.02637813189741375 2.4363715771306428e-06 5.6132564756487495 0.27834407379342074 SDAGLES(ph)DTAMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDAGLESDTAMK 12 0 Q9NR30 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 SDAGLES(0.975)DT(0.025)AMK 88.28200000000001 0.0071503 11902000.0 55474.0 70142.0 52114.0 59878.0 67194.0 60316.0 66714.0 73307.0 62112.0 56736.0 True False 64864.65253855702 77105.23420767134 53356.59540344558 56523.22978709523 54027.818056165 57152.9227797504 60394.36695246704 71382.76892518673 63020.27049564056 67021.78767807108 0.9678144195455435 1.1504502771253216 0.7961082097621125 0.8433560450311461 0.8061232015427486 0.8527513926407893 0.9011154289491972 1.0650681128958086 0.9402952782809794 1.0 16.032342547737485 -9.683075262907133 9.773840992047074 1.0000010083319377 0.9230652872139975 0.041923765786389344 0.10758301344994851 0.0 0.0 0.1127445640887374 0.027344573320710833 2.074553967658383e-10 9.683075262907133 -0.07693572111794023 SDAGLES(ph)DTAMK ddPTM_PC-9_Lapatinib_30min_R1 5 SDAGLESDTAMK 12 0 Q9NR30 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 SDAGLES(0.722)DT(0.278)AMK;SDAGLES(0.936)DT(0.064)AMK;SDAGLES(0.935)DT(0.065)AMK;SDAGLES(0.978)DT(0.022)AMK;SDAGLES(0.5)DT(0.5)AMK 157.52 6.9748e-05 58449200.0 202226.0 235033.0 227670.0 206904.0 238544.0 229264.0 229399.0 217429.0 213874.0 186926.0 True False 199342.2201562938 234488.79552888463 208951.85143161504 222120.41037151043 224513.31091554824 219458.913160487 241276.15776207234 227531.5451035892 189785.25792693577 219235.91003676143 0.9092589809893286 1.0695729339667284 0.9530913589684191 1.0131570614242225 1.024071790419288 1.0010171833788004 1.1005321059018809 1.0378388516070964 0.8656668421478608 1.0 17.742124600238924 -4.737251522209802 24.285881411128262 1.0101422661822486 0.9092583472460303 0.18792232408543508 0.06081664305726823 2593.641402222362 2603958.4902169565 0.014855173163252704 0.8989003945444155 1.831253542342929e-05 4.737251522209802 -0.10088391893621829 SDAGLESDT(ph)AMK ddPTM_PC-9_AZD4547_30min_R2 1 SDAGLESDTAMK 12 0 Q9NR30 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 SDAGLES(0.362)DT(0.638)AMK 108.59 0.0034554000000000004 5749100.0 13643.0 14789.0 17922.0 20235.0 18563.0 17435.0 14632.0 19115.0 15902.0 18032.0 True False 17981.190207971256 19569.255035342492 17684.342569973236 15570.133377633563 15985.84787070385 16344.786693823295 15934.219654060065 16161.215969002189 16742.547255423575 17400.705168513643 1.0333598571917644 1.1246242520534635 1.0163003394812316 0.8947989881356948 0.9186896574530807 0.9393174894658282 0.9157226388096521 0.928767875352874 0.9621763654566714 1.0 14.086858152433987 -5.554910942458551 4.776544375900872 0.9330751065503852 1.0781680018415234 0.7401168148338394 0.034117531989645795 0.0794829968454413 4.40471654397751 0.008792364249879515 0.016309777508996808 2.7866925563727013e-06 5.554910942458551 0.14509289529113822 SDAGLESDT(ph)AMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDAGLESDTAMK 12 0 Q9NR30 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 SDAGLES(0.111)DT(0.889)AMK 107.39 0.0059507 12393000.0 50935.0 53501.0 43712.0 56240.0 59956.0 42863.0 54436.0 63412.0 49081.0 41855.0 True False 59557.28948789347 58812.22570420883 44754.25985868313 53089.05513254011 48208.05219774722 40615.18882400095 49279.4279974892 61747.50219056773 49798.716772870524 49442.98017600232 1.204565122811918 1.1894959708103108 0.9051691402777758 1.0737430256744 0.9750231888559484 0.8214551121195152 0.9966921051698153 1.2488628713472563 1.0071948858180046 1.0 15.593478083867003 -5.21467136530684 12.286713786792298 1.0071596442438004 1.1971909395869533 0.35419960434653774 0.1044265332238918 1.899377880801921 495.78350446981983 0.028503653051717686 0.07538174289850164 6.099983140639383e-06 5.21467136530684 0.19003129534315288 SDAGLESDT(ph)AMKK ddPTM_PC-9_Lapatinib_30min_R1 1 SDAGLESDTAMKK 13 1 Q9NR30 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 SDAGLES(0.229)DT(0.771)AMKK 59.68 0.027922000000000002 6005400.0 68865.0 69964.0 62586.0 62628.0 62065.0 62498.0 56029.0 71534.0 62849.0 57455.0 True False 67882.97247170567 69802.00265657548 57440.42066894645 67233.87204088364 58414.458724484866 59825.10622995373 58929.907467997495 74857.73078770596 55770.28379068981 67386.02019602475 1.0073747087932376 1.0358528735414658 0.8524085634060785 0.9977421406591677 0.8668631647121796 0.8877969949245191 0.8745123587440159 1.110879238304119 0.8276239437861894 1.0 16.040161702621326 -5.233649888621925 24.779065110779964 0.9282597478448296 1.0216138245350221 0.17340219300014303 0.08240532571892138 1130.945193226737 1008426.1536495216 0.020024554965363348 0.05295355255104035 5.839156447427634e-06 5.233649888621925 0.09335407669019258 SDAPTSSSFFT(ph)GLKSPAPEQFQSR ddPTM_PC-9_AZD4547_30min_R2 1 SDAPTSSSFFTGLKSPAPEQFQSR 24 1 Q9P0V3;Q9P0V3-2 Q9P0V3 SH3BP4 SH3 domain-binding protein 4 1 SDAPT(0.021)S(0.019)S(0.028)S(0.081)FFT(0.776)GLKS(0.072)PAPEQFQS(0.003)R 59.996 0.0032139000000000004 12539000.0 10474.0 10533.0 14427.0 17979.0 18751.0 16306.0 19853.0 20346.0 20334.0 24050.0 True False 13804.514127266062 13937.586265958656 14235.68855356565 13834.219322781006 16147.747315820052 15286.383242298964 21619.87853964289 17201.993204568076 21408.813727316243 23208.016820250286 0.5948166202301636 0.6005505069178223 0.6133953048993062 0.5960965742971144 0.6957831615207312 0.6586682248937679 0.9315694101349643 0.7412090976062367 0.9224749315346868 1.0 14.502335625806532 -7.468994998330422 0.5149443338079266 0.992357242754725 0.5714834099294193 0.8271593448603791 0.06211431565732636 0.34687275854619 0.2003202741586518 0.05878054042203477 0.04524028972546339 3.396291839990178e-08 7.468994998330422 -0.42087383282530577 SDAPTSSSFFTGLKS(ph)PAPEQFQSR ddPTM_PC-9_Lapatinib_30min_R1 1 SDAPTSSSFFTGLKSPAPEQFQSR 24 1 Q9P0V3;Q9P0V3-2 Q9P0V3 SH3BP4 SH3 domain-binding protein 4 1 SDAPTSSS(0.001)FFT(0.001)GLKS(0.984)PAPEQFQS(0.013)R 59.302 0.0023434000000000003 8055400.0 17726.0 12233.0 12864.0 10332.0 13151.0 11923.0 12226.0 12101.0 17560.0 15151.0 True False 17473.223989449718 12204.67524009328 11806.371576476 11091.849746541617 12377.484035860793 11413.081083870498 12859.002457722561 12663.256636872402 15582.207885002344 17769.830162561502 0.9833084407448817 0.6868200274534301 0.6644054258520906 0.6241955969793432 0.696544869738732 0.6422729412415112 0.7236423950080652 0.7126267680122277 0.8768912106898936 1.0 14.117142272238427 -8.450134669012558 2.3573090828899423 0.9991149256503429 0.7063045493834091 0.4851044074580443 0.09506211283326624 0.22943361897695247 2.742378078714959 0.09085413377895034 0.025012372272830808 3.5470338332011267e-09 8.450134669012558 -0.29281037626693374 SDAS(ph)DMNSDTSPSCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDASDMNSDTSPSCR 15 0 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 S(0.319)DAS(0.573)DMNS(0.089)DT(0.014)S(0.004)PSCR 65.241 0.030212 3960400.0 6774.9 7017.2 7628.1 6293.7 7488.1 7128.6 6885.7 5164.5 6157.0 4860.0 True False 7921.756759625594 7713.821240940809 7809.982833730344 5941.084393450701 6020.860558775622 6754.763666816911 6233.436647849058 5028.937347240068 6247.034477100382 5741.079528261171 1.3798374888607223 1.343618600468531 1.360368341055849 1.0348375012408348 1.0487331745078943 1.1765668170186034 1.0857603726205496 0.875956746894814 1.0881288869712717 1.0 12.487106325331942 -5.760234847862687 24.99481803446683 1.0465402936059527 1.3595092638970752 0.8015041457389229 0.07228258981409523 14.107063191191807 292716.30585925916 0.021184891038518665 0.034227004593983194 1.7368613544969803e-06 5.760234847862687 0.3129689702911225 SDASDMNSDT(ph)SPSCR ddPTM_PC-9_AZD4547_30min_R2 1 SDASDMNSDTSPSCR 15 0 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 SDASDMNS(0.001)DT(0.497)S(0.497)PS(0.006)CR 81.128 0.022345 6128200.0 14558.0 12644.0 17788.0 29559.0 21306.0 17818.0 17068.0 25437.0 19174.0 21579.0 True False 19187.141174788943 16730.92573310369 17552.119497527277 22744.629231997566 18348.02966833035 16703.83764327752 18587.018934902768 21506.29613410979 20187.498495503183 20823.525778136413 0.9214165448837879 0.8034626754067875 0.8428985410317048 1.0922563966510517 0.8811202225703199 0.8021618347079175 0.8925971102558503 1.032788412646731 0.9694563116059326 1.0 14.345926741749814 -7.749785492015933 24.227477869094784 1.0008417580262299 0.8896014945547631 0.29220511302766294 0.07836786088119994 196.1889095319074 407863.4843590859 0.03959915664591652 0.022595158161780943 1.7791579598881053e-08 7.749785492015933 -0.11124026347146676 SDASDMNSDTS(ph)PSCR ddPTM_PC-9_AZD4547_30min_R2 2 SDASDMNSDTSPSCR 15 0 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 SDASDMNS(0.001)DT(0.191)S(0.794)PS(0.015)CR;SDASDMNSDT(0.003)S(0.963)PS(0.034)CR 199.33 9.4151e-50 5025800.0 12475.0 14658.8 25728.8 30818.0 24155.7 23074.8 20849.9 27445.0 19336.5 21918.2 True False 16441.79050388048 19396.97043154228 25387.619301100734 23713.38623335365 20802.098012732906 21631.929108266908 22705.500708391693 23204.00587335941 20358.58791375287 21150.850489380864 0.7773583625932845 0.9170775634427017 1.200311983380858 1.1211552105320468 0.9835111842512879 1.0227451193571424 1.0735029647999907 1.0970720011949102 0.9625422828256592 1.0 14.368428055761937 -5.004731363792256 4.942677186776292 1.0605803969085401 0.801091774658299 0.6323900679962446 0.06801899389577636 0.103143404789663 7.518462193423767 0.017825812662798316 0.06400639971502566 9.891647609685324e-06 5.004731363792256 -0.25948862225024116 SDASDMNSDTS(ph)PSCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SDASDMNSDTSPSCR 15 0 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 SDASDMNS(0.003)DT(0.221)S(0.774)PS(0.002)CR;SDASDMNS(0.001)DT(0.008)S(0.987)PS(0.004)CR 120.21 7.498e-05 14995800.0 16039.699999999999 15289.3 18703.0 17664.9 24517.5 20859.1 21251.6 21390.1 17999.4 14309.8 True False 18754.904411484546 16807.12066053644 19148.950451522483 16675.192923378512 19713.471875346382 19765.21207565309 19238.494599739897 20828.63253968434 18262.60717348069 16904.05346368553 1.1094915460232744 0.9942657065444492 1.1328022886735183 0.9864612034741447 1.1661979132813465 1.1692587294588308 1.1380994884492868 1.2321679285048326 1.080368517096429 1.0 14.04508161485922 -6.283358709332322 24.94867784018492 1.144890198036033 1.056866437086439 0.19515455729434206 0.07160934707001272 1020.10352567866 1161082.5661934032 0.020639086382838793 0.02342073636252857 5.207644034997194e-07 6.283358709332322 -0.08802376094959419 SDASDMNSDTS(ph)PSCR ddPTM_PC-9_Lapatinib_30min_R1 4 SDASDMNSDTSPSCR 15 0 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 SDASDMNS(0.009)DT(0.036)S(0.945)PS(0.01)CR;SDASDMNS(0.024)DT(0.22)S(0.754)PS(0.001)CR;SDASDMNSDT(0.031)S(0.969)PSCR;SDASDMNSDT(0.086)S(0.901)PS(0.013)CR 211.45 1.5118e-13 20275700.0 48937.0 60720.9 68118.0 54918.2 62164.0 54942.7 53672.5 51307.2 59276.7 44194.5 True False 48239.1494060533 60580.30448673094 62517.60098308396 58957.06762974465 58507.63573912635 52592.92879868927 56451.399428440585 53691.119818142295 52600.33383467649 51833.46043953039 0.9306565488200376 1.1687489890319929 1.2061243924861593 1.1374325991320753 1.128761908678317 1.0146520867547495 1.0890918520537047 1.0358389998055229 1.0147949488350434 1.0 15.66159609185781 -6.7544933152898246 24.886105219693082 1.0367540302595717 1.123748864851644 0.2464764362586933 0.07167245056222588 221.6931890586361 794272.5991568632 0.02424837784804271 0.023741952439989812 1.7599757533404214e-07 6.7544933152898246 0.08699483459207236 SDATNYASHS(ph)PPVNR ddPTM_PC-9_AZD4547_30min_R2 1 SDATNYASHSPPVNR 15 0 Q96FJ0;Q96FJ0-2 Q96FJ0 STAMBPL1 AMSH-like protease 1 SDATNYAS(0.009)HS(0.991)PPVNR 62.556000000000004 0.024163999999999998 9083400.0 13382.0 10537.0 22659.0 26468.0 26170.0 26667.0 23230.0 34171.0 26596.0 22341.0 True False 17637.197637108504 13942.879187734401 22358.52685487242 20366.211526523613 22536.747227081803 24999.50827440123 25297.424997527025 28890.657121463453 28001.81026318986 21558.848390071173 0.8180955363659977 0.6467358058956307 1.0370928191679076 0.9446799364247664 1.0453595117567132 1.1595938624400104 1.1734126303878845 1.3400835053308744 1.2988546399392076 1.0 14.395992495195216 -5.897216404830123 0.7144422269447142 1.234167148345407 0.6953621124019026 0.6769643153249503 0.11415035944336838 0.5209652219854212 0.49370522642772824 0.06070152891762149 0.18149988430125052 1.2670203642789765e-06 5.897216404830123 -0.5388050359435045 SDATNYASHS(ph)PPVNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDATNYASHSPPVNR 15 0 Q96FJ0;Q96FJ0-2 Q96FJ0 STAMBPL1 AMSH-like protease 1 S(0.018)DAT(0.004)NYAS(0.016)HS(0.962)PPVNR 120.59 0.0013085999999999998 0.0 3438.9 5171.3 5872.2 5166.6 8700.0 5377.2 6482.3 3932.0 5815.7 5122.4 True False 4021.037848628976 5684.672488068914 6012.215518442513 4877.1321523432025 6995.297453472558 5095.210165980401 5868.249616212143 3828.789166298372 5900.743610276546 6051.050571103913 0.6645189626791377 0.9394521531873168 0.9935820974878556 0.8059975858792816 1.1560467676270607 0.8420372803215335 0.9697902120063722 0.6327478379675603 0.9751601876300389 1.0 12.56296992657688 -4.758319191283787 24.79424874231571 0.9170201402288879 0.6645185777284006 0.25534447751232303 0.1324040973849069 114.1473940265916 906887.443052924 0.03201076873983311 0.2208745610052589 1.744539505989605e-05 4.758319191283787 -0.2525015625004873 SDATNYASHS(ph)PPVNR ddPTM_PC-9_Lapatinib_30min_R1 2 SDATNYASHSPPVNR 15 0 Q96FJ0;Q96FJ0-2 Q96FJ0 STAMBPL1 AMSH-like protease 1 SDATNYAS(0.001)HS(0.999)PPVNR;SDATNYAS(0.002)HS(0.998)PPVNR 101.61 0.0016407 10460600.0 26677.1 29457.8 37216.8 29869.0 29966.0 28696.0 31329.8 32191.0 37625.5 27642.1 True False 26296.67966201902 29389.592273981827 34156.978365002506 32065.665900063057 28203.45879542273 27468.73897364321 32951.90374611128 33686.711379023196 33387.71997592003 32420.00015421698 0.8111252170552048 0.9065265926644057 1.0535773659013876 0.9890705042421836 0.8699401191012706 0.8472775707272863 1.0164066498878506 1.0390719068100143 1.0298494699907388 1.0 14.984596477267583 -7.389529332860092 7.828762684412261 1.0260928447923268 0.9206576201117166 0.3908751462001493 0.06586354332093876 0.3441023577727253 20.2735588725999 0.030619221965128847 0.020561434955273038 4.07822015968527e-08 7.389529332860092 -0.10543522468061017 SDDDGFEIVPIEDPAK ddPTM_PC-9_Lapatinib_30min_R1 1 SDDDGFEIVPIEDPAK 16 0 Q8IY81 Q8IY81 FTSJ3 pre-rRNA processing protein FTSJ3 0 115.14 0.0029583 0.0 9173.1 10681.0 9718.9 7869.3 8903.6 8210.2 8987.6 8987.6 6676.8 9622.6 False True 9042.28991185948 10656.268800738686 8919.849558038914 8448.03457321525 8379.907753151101 7859.068884910977 9452.933951335455 9405.196706846906 5924.7884741790285 11285.853588691467 0.8012056722869363 0.9442146947056241 0.7903566609243174 0.7485507858865244 0.7425143067200384 0.6963645968955188 0.837591403879932 0.8333615736669668 0.5249747772836362 1.0 13.462227918291944 -5.459939494221925 7.09876263796418 0.7614105920670752 0.8724038449874458 0.10509338228435094 0.1178116364132913 0.5092702760620132 49.172296430828524 0.029175090418126253 0.06073058384769275 3.4678516109266327e-06 5.459939494221925 0.11099325292037066 SDDY(ph)MPMSPASVSAPK ddPTM_PC-9_Lapatinib_30min_R1 1 SDDYMPMSPASVSAPK 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 S(0.002)DDY(0.829)MPMS(0.166)PAS(0.002)VS(0.001)APK 85.006 0.0027795000000000003 4916700.0 35894.0 28118.0 38797.0 38050.0 60013.0 73628.0 71115.0 63445.0 80905.0 69629.0 True False 35382.144977846576 28052.89449856478 35607.260420750885 40848.32393107907 56483.15333009764 70479.10207525101 74796.98673163264 66392.88631735976 71792.62693258066 81664.27987518947 0.4332634173952481 0.3435148701664798 0.43602001358697795 0.5001981771407165 0.6916506631347624 0.8630346362322281 0.9159082385340033 0.8129978788624654 0.8791190841614471 1.0 16.317417558095983 -6.371414417244458 1.4577533957342006 0.893778136777678 0.39089775442025065 0.9528899683612196 0.04922790607380682 0.07794198422015772 0.3340145096311215 0.018964880390032697 0.023857596846139136 4.2519248765155117e-07 6.371414417244458 -0.5028803823574274 down SDDYMPMS(ph)PASVSAPK ddPTM_PC-9_AZD4547_30min_R2 4 SDDYMPMSPASVSAPK 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 SDDY(0.002)MPMS(0.992)PAS(0.006)VSAPK;SDDYMPMS(0.999)PASVSAPK;SDDY(0.001)MPMS(0.989)PAS(0.007)VS(0.004)APK;SDDYMPMS(0.929)PAS(0.06)VS(0.011)APK 129.29 1.0699e-05 93002600.0 154980.0 150061.0 194533.0 251409.0 235136.0 209053.0 183230.0 243410.0 178665.0 192132.0 True False 204260.41621574352 198565.28364720603 191953.3653143959 193450.53928032986 202491.42514280102 195980.88286227977 199537.11503645594 205796.577505353 188108.86714817333 185405.51716042956 1.1016954583881071 1.0709782895801825 1.035316360884237 1.0433914925678238 1.0921542586437014 1.0570391100751304 1.0762199426018075 1.1099808714283257 1.014580741874065 1.0 17.500324649692395 -8.422246494455884 6.2014821676053105 1.0003881654026099 1.07105416094341 0.575889223436727 0.02275675343580159 0.1630086865895571 7.7652342972399815 0.022790535285535467 0.005906379110957731 3.782278513159356e-09 8.422246494455884 0.07066599554080022 SDDYMPMS(ph)PASVSAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SDDYMPMSPASVSAPK 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 SDDY(0.005)MPMS(0.621)PAS(0.334)VS(0.04)APK;SDDY(0.003)MPMS(0.991)PAS(0.005)VS(0.001)APK;SDDYMPMS(0.987)PAS(0.013)VSAPK;SDDY(0.001)MPMS(0.993)PAS(0.003)VS(0.003)APK 111.22 0.00028881 67912800.0 240545.0 219855.8 199355.3 269927.0 443189.0 499387.0 535320.0 542959.0 517637.0 447000.0 True False 281264.5175196883 241681.63084763667 204108.6864111857 254803.86530514088 356349.29690885585 473198.2665994301 484610.61421882425 528706.9015626127 525206.461852008 528037.5615499477 0.5326600567847731 0.4576978011530638 0.3865419835135702 0.48254875004955244 0.6748559626380828 0.8961450871230677 0.9177578443403677 1.0012675992418045 0.9946384501707992 1.0 19.010281032684205 -6.61992074342029 1.6460153541061628 0.981331093281972 0.4507015238559215 0.9726318584118155 0.039652585183592985 0.0578338925573385 0.322370457231642 0.01741588709670664 0.017710156637846926 2.3992707340268463e-07 6.61992074342029 -0.5306295694260506 SDDYMPMS(ph)PASVSAPK ddPTM_PC-9_Lapatinib_30min_R1 5 SDDYMPMSPASVSAPK 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 SDDYMPMS(0.798)PAS(0.2)VS(0.003)APK;SDDYMPMS(0.928)PAS(0.067)VS(0.005)APK;SDDYMPMS(0.99)PAS(0.009)VS(0.002)APK;SDDY(0.001)MPMS(0.991)PAS(0.008)VSAPK;SDDYMPMS(0.998)PAS(0.002)VSAPK 138.39 1.3708e-05 33340600.0 184761.0 177220.0 183384.0 163826.0 278416.0 338788.0 310998.0 276782.0 386683.0 313508.0 True False 182126.27425898184 176809.6579783644 168306.87540271104 175874.31054751505 262040.11826691678 324298.82699340134 327099.9547150989 289642.30216236843 343130.6885874925 367697.44007684855 0.49531558941753184 0.4808563745818064 0.4577319748746007 0.47831257816414885 0.7126514620611732 0.8819719466244396 0.8895899700763084 0.7877191152101395 0.933187591721548 1.0 18.488159606916852 -6.465986552184979 2.3483047644624664 0.8865943834967716 0.4728360875861036 0.9362544472368771 0.05159911356630133 0.06935349350140997 0.7588281253900115 0.017830962485633997 0.019867008091431288 3.4199003198163417e-07 6.465986552184979 -0.41375829591066793 SDEGHPFR ddPTM_PC-9_AZD4547_30min_R2 3 SDEGHPFR 8 0 Q9NQC3-5;Q9NQC3;Q9NQC3-2;Q9NQC3-4;A0A0U1RQR6;H7C106;F8W914;Q9NQC3-3;Q9NQC3-6 Q9NQC3-5 RTN4 Reticulon-4;Reticulon 0 ;; 69.598 0.032673 20304000.0 211313.0 206722.0 517660.0 574340.0 498350.0 446910.0 368070.0 645790.0 399610.0 455150.0 False True 278506.1384165534 273540.84383096034 510795.4901669644 441934.7864645442 429162.7046471614 418964.6470511368 400827.5169539286 545997.9942778922 420732.56878001586 439215.3370368786 0.6340993014849312 0.6227943807162466 1.1629727996590329 1.0061916085308225 0.977112291985211 0.9538934816749319 0.9125990901366753 1.2431214218551925 0.9579186638117994 1.0 18.744568907379012 -5.249445046214093 24.79103744353975 1.0262266403168396 0.6284467533170509 0.7337011039998821 0.09597787455911463 331.85179944111024 685899.7131359115 0.02453402951292467 0.06381676430150678 5.6306036016200414e-06 5.249445046214093 -0.3977798869997887 SDEGHPFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SDEGHPFR 8 0 Q9NQC3-5;Q9NQC3;Q9NQC3-2;Q9NQC3-4;A0A0U1RQR6;H7C106;F8W914;Q9NQC3-3;Q9NQC3-6 Q9NQC3-5 RTN4 Reticulon-4;Reticulon 0 ; 76.827 0.020484 16572000.0 193055.0 197894.0 303110.0 264790.0 372710.0 269520.0 263220.0 235710.0 261650.0 188320.0 False True 225735.39848994408 217539.6084841159 310337.2919510756 249954.67476076246 299680.151021121 255385.89673715646 238285.896052228 229522.8622553886 265476.13625683164 222460.92525970022 1.0147193185788528 0.977877837333279 1.3950193346934467 1.123589117814583 1.347113659044955 1.1480033917822634 1.071135956905932 1.0317446175657334 1.193360748396221 1.0 17.763192426764604 -7.171164693058971 4.924584035384031 1.0769511150982793 1.177054956290544 0.11170041149510646 0.12929822531197321 0.5399580497633537 21.864505563921266 0.052306117121752205 0.039994283567021366 6.742722818209765e-08 7.171164693058971 0.10010384119226456 SDEGHPFR ddPTM_PC-9_Lapatinib_30min_R1 1 SDEGHPFR 8 0 Q9NQC3-5;Q9NQC3;Q9NQC3-2;Q9NQC3-4;A0A0U1RQR6;H7C106;F8W914;Q9NQC3-3;Q9NQC3-6 Q9NQC3-5 RTN4 Reticulon-4;Reticulon 0 79.47399999999999 0.017341 12973000.0 122270.0 96636.0 119110.0 80639.0 112140.0 101370.0 75965.0 80152.0 156140.0 58482.0 False True 120526.4073784281 96412.24527929837 109317.23557789647 86569.46106381841 105544.14567572268 97034.64140501164 79898.0960004004 83876.15452926198 138553.8689729081 68590.53577763333 1.7571871397705359 1.405620238801771 1.5937655878982608 1.262119621640976 1.5387566882097392 1.4146943205049822 1.164855983330201 1.222853176146397 2.020014385397017 1.0 16.06572190450979 -1.522881343290877 0.9205378654647616 1.3902555738893032 199.3572195342846 0.13631526334462418 0.26617320146555623 2095.1643357332077 4.180908135074617 0.08354680680185135 872279.84343176 0.029999820536326605 1.522881343290877 197.9669639603953 SDEGQLS(ph)PATR ddPTM_PC-9_AZD4547_30min_R2 1 SDEGQLSPATR 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 SDEGQLS(0.63)PAT(0.37)R 115.37 0.0013659 179140000.0 37702.0 40473.0 53134.0 52157.0 46738.0 42480.0 46463.0 69171.0 43550.0 43680.0 True False 49690.45174968352 53555.10575734782 52429.40844286114 40133.00946761717 40249.23545660487 39823.71888463513 50598.11698924232 58482.21134145184 45851.9640909129 42150.776495157246 1.1788739349888966 1.2705603599853215 1.2438539168758804 0.9521297780179234 0.9548871646819875 0.9447920583197447 1.2004077076742725 1.3874527637271625 1.0878082897519312 1.0 15.36327158806898 -5.718733780991592 24.985852216556726 1.086248774501219 1.235042831008609 0.22650734679007078 0.1307460442502624 256.08249794981225 149824.74587185797 0.040385532769083396 0.069949167035672 1.911024342078264e-06 5.718733780991592 0.14879405650738997 SDEGQLS(ph)PATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDEGQLSPATR 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 SDEGQLS(0.961)PAT(0.039)R 110.15 0.0019722000000000003 7256100.0 16038.0 18410.0 22387.0 24430.0 25799.0 18694.0 21693.0 20866.0 18787.0 14405.0 True False 18752.91663506108 20237.623132548644 22920.790983170275 23061.266303128632 20743.871149671115 17713.65373109381 19638.08199628065 20318.289609354488 19061.724333487877 17016.51247008275 1.102042305556509 1.189293233153916 1.3469734778773275 1.3552287135024492 1.2190436310696182 1.040968515859917 1.1540603299769538 1.1940337154911556 1.1201898371949526 1.0 14.054647766886031 -6.5852517715743 7.522768961745621 1.1179000478372405 1.2556154272162987 0.3992049633987429 0.08555723867845659 0.27275315706825143 27.95858241996878 0.030105495622862497 0.03012145422982663 2.598652621279005e-07 6.5852517715743 0.1377153793790582 SDEGQLSPATR ddPTM_PC-9_Lapatinib_30min_R1 1 SDEGQLSPATR 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 99.568 0.020771 2163400.0 9917.9 11633.0 6477.9 8502.6 12108.0 11951.0 13244.0 9993.9 11497.0 9327.5 False True 9776.468927279893 11606.064503229392 5945.312067417125 9127.90956784212 11395.831245243902 11439.883589141695 13929.709516610314 10458.25307852567 10202.086791222786 10939.745946887491 0.8936650791293224 1.060908046638092 0.5434597929679207 0.8343803971461637 1.041690666361971 1.0457174823512698 1.2733119749068311 0.9559868327199305 0.9325707233745607 1.0 13.417291614442135 -6.2643820078512125 6.500012409401923 1.0516509623173977 0.8281039498127749 0.3255987875957259 0.14653392543682012 0.17686666648680424 41.54337774953548 0.04676285643400691 0.056417198339405596 5.440239158494243e-07 6.2643820078512125 -0.22354701250462283 SDGAPASDSKPGSSEAAPSSK ddPTM_PC-9_Lapatinib_30min_R1 1 SDGAPASDSKPGSSEAAPSSK 21 1 P80723;P80723-2 P80723 BASP1 Brain acid soluble protein 1 0 108.12 7.5096e-05 4179600.0 25276.0 19572.0 21464.0 19234.0 19526.0 17767.0 30612.0 20989.0 22397.0 21917.0 False True 24915.55960494929 19526.682236500106 19699.312773436024 20648.532522743095 18377.519069593036 17007.146826899876 32196.939574333654 21964.22556411165 19874.414009134274 25705.324247433207 0.969276223288147 0.7596357100397181 0.7663514602583972 0.8032784307245198 0.7149304514775033 0.661619618690401 1.2525397176247899 0.8544621088101962 0.7731633267033706 1.0 14.649779589934267 SDGEAKPEPSPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 SDGEAKPEPSPSPR 14 1 P26358;K7EJL0;K7ERQ1;K7ENQ6 P26358 DNMT1 DNA (cytosine-5)-methyltransferase 1 1 SDGEAKPEPS(0.008)PS(0.992)PR 60.541000000000004 0.026151 4357300.0 31344.0 29738.0 27844.0 29140.0 35271.0 29495.0 22557.0 23360.0 33495.0 27383.0 True False 30897.028812214387 29669.14348809727 25554.773800948224 31283.05280819035 33196.42912545402 28233.567606203185 23724.891087751344 24445.390879872684 29722.440382013323 32116.115064446032 0.962041291426894 0.923808606008587 0.7956994097719651 0.974060926902771 1.0336377565854453 0.8791090562961335 0.7387223218046025 0.761156535615194 0.9254681122660875 1.0 14.971009766917877 -6.997251596534604 24.993061326234997 0.8325020529197618 0.9337029912273802 0.13538903364504928 0.09063373443963353 137.3751622442134 1249228.7422126564 0.03253138334397298 0.02853323473760379 1.0063484996883305e-07 6.997251596534604 0.10120093830761845 SDGS(ph)ENLCTPQQSR ddPTM_PC-9_AZD4547_30min_R2 1 SDGSENLCTPQQSR 14 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 S(0.001)DGS(0.999)ENLCTPQQSR 169.94 6.5666e-19 0.0 7809.7 8297.8 11319.0 16170.0 12085.0 10355.0 10515.0 11677.0 9980.5 11217.0 True False 10293.022148148728 10979.901577676983 11168.90266429678 12442.256324009617 10407.206352284436 9707.500213050766 11450.814629745873 9872.58796076582 10508.048854405422 10824.296244189087 0.9509183706676941 1.0143755612353489 1.0318363810758313 1.1494748520661668 0.9614672508498129 0.8968250677970994 1.0578807500666039 0.9120766595856815 0.9707835611064841 1.0 13.401985608841091 -6.415072848564892 20.697135056793236 0.9631532748636563 1.0373136697135905 0.23598830769433 0.06164606592976792 11.048339182623568 2107.2339837023196 0.0192469549201235 0.021823947227454316 3.845272760225806e-07 6.415072848564892 0.0741603948499342 SDGS(ph)ENLCTPQQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDGSENLCTPQQSR 14 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 S(0.001)DGS(0.999)ENLCTPQQSR 106.52 0.0032486999999999993 0.0 3144.2 5870.1 4352.5 5578.1 6093.5 5716.6 5688.1 5972.9 4587.9 3121.9 True False 3676.4509592192953 6452.844733860606 4456.280106948172 5265.577141444201 4899.5224175557505 5416.811432500848 5149.281989722213 5816.117703810665 4654.9893580459375 3687.8757570531966 0.9969020654201675 1.7497456961556541 1.2083596087599682 1.4278076291950976 1.328548666040399 1.468816139519071 1.3962731742993306 1.5770915526877847 1.2622413727314703 1.0 11.848574337473122 -8.535421016958301 21.67126136565981 0.99999998819909 1.402484943502596 0.28437136467719404 0.19073694976859218 355.3520740339615 614000.0144131104 0.16616164621134055 0.042902752569866934 2.9146001508383962e-09 8.535421016958301 0.4024849553035059 SDGS(ph)ENLCTPQQSR ddPTM_PC-9_Lapatinib_30min_R1 1 SDGSENLCTPQQSR 14 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 S(0.001)DGS(0.999)ENLCTPQQSR 147.75 0.00020773 3948600.0 7797.6 9627.4 10236.0 10101.0 9210.0 10384.0 9630.1 9162.6 10422.0 8027.8 True False 7686.40479409529 9605.108346805697 9394.435592102645 10843.861235948207 8668.285907556683 9939.900526286281 10128.699457558818 9588.327845715816 9248.164611474636 9415.39453362889 0.8163656622823205 1.0201493216773028 0.9977739709736659 1.1517160749044846 0.9206503112106704 1.0557072771389469 1.0757594300889062 1.0183670807919158 0.9822386707687117 1.0 13.20080583407241 -4.759647228737312 5.535242449182725 1.0283573312416876 0.8059530339519193 0.5359187163772472 0.058121885811705326 0.11517617553499171 11.306747639292531 0.013965237059992126 0.09824958847923193 1.7392129932368767e-05 4.759647228737312 -0.2224042972897683 SDGSDTTEQESTNLPS(ph)PNK ddPTM_PC-9_AZD4547_30min_R2 5 SDGSDTTEQESTNLPSPNK 19 0 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 SDGSDTTEQESTNLPS(1)PNK;SDGSDTTEQESTNLPS(1)PNK;SDGSDTTEQESTNLPS(1)PNK;SDGSDTTEQESTNLPS(1)PNK;SDGSDTTEQESTNLPS(1)PNK 281.61 8.920699999999999e-93 45450000.0 139692.0 132443.0 131107.0 175603.0 157247.0 143968.0 141804.0 143242.0 140830.0 147347.0 True False 184111.1502258979 175252.60968597367 129368.43551620796 135120.441389305 135415.9683307962 134965.6582011097 154424.28128925228 121107.24027370196 148273.98628985678 142188.42637893633 1.2948392138136213 1.2325377961418627 0.9098380143221874 0.9502914184393957 0.9523698361349655 0.9492028404718558 1.0860538035473226 0.8517376790636082 1.0427992633852086 1.0 17.117444514040827 -5.192147615962221 5.144134295264272 0.964975648909692 1.2751759139684853 0.7798558613390043 0.06301898833439884 0.08702688476182248 4.393379453747839 0.015288781942255202 0.04246757778039142 6.424693059663397e-06 5.192147615962221 0.3102002650587933 SDGSDTTEQESTNLPS(ph)PNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SDGSDTTEQESTNLPSPNK 19 0 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 SDGSDTTEQESTNLPS(1)PNK;SDGSDTTEQESTNLPS(1)PNK;SDGSDTTEQESTNLPS(1)PNK;SDGSDTTEQESTNLPS(1)PNK;SDGSDTTEQESTNLPS(1)PNK 291.7 2.6706999999999997e-118 38645400.0 162639.0 169466.0 165807.0 211913.0 209167.0 192015.0 214566.0 226779.0 185372.0 159602.0 True False 190170.57043332653 186289.46451822293 169760.46770654953 200040.20164121524 168182.2278678733 181945.3953769113 194240.7551566846 220826.2915422126 188082.71481063004 188536.579191263 1.0086667067423871 0.9880812801278183 0.9004113071041464 1.0610153345271118 0.8920403063919972 0.9650402916896821 1.030255009345613 1.1712649740939287 0.99759269854911 1.0 17.524484931607816 -7.4091736330738645 4.3954019926167955 1.0693200406177004 0.9680663012272979 0.2683451286923385 0.06456054915166752 0.25854632045862447 8.149481573887902 0.027212003837464197 0.017682545156143356 3.897861171096056e-08 7.4091736330738645 -0.1012537393904025 SDGSDTTEQESTNLPS(ph)PNK ddPTM_PC-9_Lapatinib_30min_R1 4 SDGSDTTEQESTNLPSPNK 19 0 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 SDGSDTTEQESTNLPS(1)PNK;SDGSDTTEQESTNLPS(1)PNK;SDGSDTTEQESTNLPS(1)PNK;SDGSDTTEQESTNLPS(1)PNK 294.39 3.7746999999999985e-121 43913000.0 306727.0 281212.0 257957.0 267010.0 307845.0 288239.0 279838.0 266993.0 301735.0 271255.0 True False 302353.0167331574 280560.87089161354 236748.77120281622 286646.8061192488 289738.1623465569 275911.6898879264 294326.64238214976 279398.4694858668 267750.42688958906 318141.065325432 0.9503740625997944 0.8818756880839101 0.7441628793209761 0.9010053632216036 0.9107222987707629 0.8672621046443393 0.9251450833015786 0.8782219585518306 0.841609135292555 1.0 18.2793070799438 SDGSENLCT(ph)PQQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDGSENLCTPQQSR 14 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 SDGSENLCT(0.998)PQQS(0.002)R 93.71600000000001 0.011339 0.0 6752.5 7186.3 8665.7 4494.3 9941.5 7860.4 6060.3 7417.1 3159.5 4338.0 True False 7895.564882045756 7899.708371397838 8872.323152850266 4242.498941717195 7993.53444065488 7448.1867865566355 5486.224511227569 7222.408984067051 3205.701710313246 5124.4450604108915 1.5407648611638485 1.5415734344441228 1.7313724799966652 0.8278943166925122 1.5598829427227652 1.4534621210202652 1.070598756851082 1.409403144911059 0.6255705100790376 1.0 12.323180064511071 -7.870806392173279 1.155940601463229 0.8639301197300431 1.437306672720576 0.3779781065994482 0.27548612198756994 0.5379343768016263 1.296075991320978 0.24081971849796796 0.08938155739213664 1.3464604703327306e-08 7.870806392173279 0.573376552990533 SDGSGESAQPPEDS(ph)SPPASSESSSTR ddPTM_PC-9_Lapatinib_30min_R1 1 SDGSGESAQPPEDSSPPASSESSSTR 26 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 SDGSGESAQPPEDS(0.944)S(0.055)PPASSESSSTR 183.79 9.101699999999998e-24 4537900.0 23548.0 21207.0 24778.0 21573.0 23210.0 20023.0 19903.0 21464.0 24573.0 14773.0 True False 23212.201201825665 21157.896494454195 22740.848485845956 23159.550385418344 21844.83343261571 19166.66296589273 20933.479953873084 22461.295798184397 21805.329974838416 17326.493366214843 1.3396941153186508 1.2211297489491009 1.3124899542678747 1.3366553690879803 1.2607763712426219 1.1062055408895408 1.2081775297182493 1.2963555477406625 1.2584964259044427 1.0 14.080692082802733 -6.5335528236335305 24.69133019183667 1.1932899863464874 1.2975599458506206 0.3389318198771507 0.08331204511958785 260.7215542863507 603097.4708932745 0.027266777525672577 0.027291618005496045 2.927164815992628e-07 6.5335528236335305 0.1042699595041332 SDGSGESAQPPEDSS(ph)PPASSESSSTR ddPTM_PC-9_AZD4547_30min_R2 1 SDGSGESAQPPEDSSPPASSESSSTR 26 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 SDGSGESAQPPEDS(0.061)S(0.932)PPAS(0.004)S(0.001)ESSSTR 170.93 1.4377999999999998e-35 0.0 7817.4 8987.7 10948.0 16157.0 15352.0 12289.0 9775.8 11298.0 10145.0 10097.0 True False 10303.170587978771 11892.798260947175 10802.82236670388 12432.253273161617 13220.639794809324 11520.566887318297 10645.827261766019 9552.153702212232 10681.243988572012 9743.507103287606 1.0574396342875685 1.2205870160380308 1.1087201201976695 1.275952605296176 1.3568666451065121 1.1823839984096778 1.0926073280301665 0.9803609317418357 1.0962422334528807 1.0 13.250225437854136 -7.3675943941307835 3.124500267037452 1.029952678846144 1.2084122737062313 0.4793148648574481 0.0825140861886829 0.2392257750312585 4.455897431371167 0.040349523975714716 0.025628257884030635 4.2894894683014533e-08 7.3675943941307835 0.17845959486008733 SDGSLEDGDDVHR ddPTM_PC-9_Lapatinib_30min_R1 1 SDGSLEDGDDVHR 13 0 Q9NRX5 Q9NRX5 SERINC1 Serine incorporator 1 0 161.25 8.5034e-13 0.0 19646.0 17053.0 18356.0 15848.0 17345.0 18530.0 15090.0 18491.0 18735.0 11477.0 False True 19365.844437364853 17013.51482623319 16846.840536209085 17013.5147873782 16324.801201582053 17737.515095539744 15871.286364062942 19350.159364714284 16624.867011703813 13460.784157858787 1.438686202100531 1.2639319245231504 1.2515497120109027 1.263931921636618 1.2127674740294512 1.3177178155095877 1.1790759125126329 1.4375209599818977 1.2350593261684346 1.0 13.716474836132267 -8.550384427281823 23.15630049334996 0.999999997855637 1.2892843997754566 0.5425729293758714 0.08112557480452058 2595.4296578620965 2185019.789456309 0.07515026013367061 0.0194037136990969 2.8158892686740875e-09 8.550384427281823 0.28928440191981963 SDHTLT(ph)SPGGGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDHTLTSPGGGGK 13 0 Q9Y618;Q9Y618-4;C9J0Q5;A0A384DVL6;C9J7T7;H7C2R5 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 S(0.001)DHTLT(0.632)S(0.367)PGGGGK 92.265 0.0098639 10924000.0 30091.0 36285.0 107090.0 98649.0 133690.0 139230.0 98750.0 83381.0 101250.0 63658.0 True False 35184.81197565925 39887.135000789116 109643.43174108655 93122.01635437325 107494.40420169508 131928.5336995929 89395.68511191235 81192.33709947222 102730.58970381893 75198.6914835493 0.4678912795092504 0.5304232588876224 1.458049729031156 1.2383462333881823 1.4294717378853714 1.7543993265953837 1.188793093979153 1.079704121144636 1.3661220385236703 1.0 16.198419937640942 -5.254369703590457 23.884249419705302 1.3298347695525357 0.49915699989553847 0.7215880477794453 0.20236423006322632 150.04311430622903 506900.01595053513 0.053353575271388905 0.13453579484404285 5.567116330338422e-06 5.254369703590457 -0.8306777696569971 SDHTLT(ph)SPGGGGK ddPTM_PC-9_Lapatinib_30min_R1 1 SDHTLTSPGGGGK 13 0 Q9Y618;Q9Y618-4;C9J0Q5;A0A384DVL6;C9J7T7;H7C2R5 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 SDHTLT(0.626)S(0.374)PGGGGK 80.74600000000001 0.026025 11559000.0 114030.0 85385.0 248130.0 116350.0 174210.0 200640.0 114860.0 126820.0 251230.0 112380.0 True False 112403.91128945914 85187.29627853875 227729.70920949834 124906.76713222176 163963.31031003804 192059.094914684 120806.88878570385 132712.52017917152 222933.8318308166 131804.7332630628 0.8528063333288457 0.6463143937973568 1.7277809648533897 0.947665262391801 1.2439865113401614 1.4571486938284863 0.9165595634914804 1.0068873620365129 1.6913947345568656 1.0 17.00804265458956 -5.222594490593847 24.99918551254595 1.233804344396331 0.7495601218499053 0.32808324281420154 0.28519880840628226 622.9110172578597 400881.504351987 0.06948805301106697 0.18384077007324084 5.989706048218617e-06 5.222594490593847 -0.48424422254642563 SDHTLTS(ph)PGGGGK ddPTM_PC-9_AZD4547_30min_R2 2 SDHTLTSPGGGGK 13 0 Q9Y618;Q9Y618-4;C9J0Q5;A0A384DVL6;C9J7T7;H7C2R5 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 SDHTLT(0.03)S(0.97)PGGGGK;SDHTLT(0.01)S(0.99)PGGGGK 98.654 0.0015328 37349000.0 43024.0 34150.1 204263.0 377670.0 302782.0 220281.0 103701.0 264478.0 158541.0 233413.0 True False 56704.7370452067 45188.45198339646 201554.33915692693 290604.0164433345 260745.94569775587 206506.79424732347 112930.18810454391 223609.00219983002 166921.15359213363 225241.28191538824 0.2517510847168229 0.2006224240917412 0.8948374713683289 1.2901898531748712 1.1576294695201785 0.9168248044552403 0.50137429135644 0.9927531947000222 0.7410770893003418 1.0 17.781111741270998 -5.275967095504609 6.574607079365968 0.9421902137121005 0.22324171206632867 0.662586502274037 0.2029052175378012 0.08944742428859515 19.591109374462448 0.05819156902624687 0.1318116571193103 5.297035755749338e-06 5.275967095504609 -0.7189485016457718 SDHTLTS(ph)PGGGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDHTLTSPGGGGK 13 0 Q9Y618;Q9Y618-4;C9J0Q5;A0A384DVL6;C9J7T7;H7C2R5 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 SDHTLT(0.185)S(0.815)PGGGGK 94.71700000000001 0.0020954999999999997 9453800.0 27101.0 34143.0 121460.0 106100.0 137250.0 153120.0 93807.0 113470.0 121480.0 67497.0 True False 31688.664030851098 37532.49139677392 124356.06703961495 100155.56098084121 110356.847757369 145090.11764764556 84920.92185613346 110491.53273140277 123256.41518241884 79733.6717940421 0.39743139025009705 0.47072322837110886 1.5596430496871607 1.2561262855114756 1.384068302315599 1.819684386571635 1.0650572078944314 1.3857574879633097 1.5458514879485192 1.0 16.282901487347196 -5.253579030071257 24.02096787542642 1.391402086414222 0.43407701102041296 0.7334725324951819 0.2272340266110396 159.41634616718443 487165.53315363516 0.05582352017081942 0.14171139535324642 5.577261015556254e-06 5.253579030071257 -0.9573250753938091 SDHTLTS(ph)PGGGGK ddPTM_PC-9_Lapatinib_30min_R1 1 SDHTLTSPGGGGK 13 0 Q9Y618;Q9Y618-4;C9J0Q5;A0A384DVL6;C9J7T7;H7C2R5 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 SDHTLT(0.214)S(0.785)PGGGGK 76.01 0.010042 13884000.0 111610.0 63471.0 215940.0 109490.0 154250.0 188500.0 103040.0 146120.0 242130.0 94586.0 True False 110018.42093323296 63324.036799146605 198186.2467525052 117542.25984793295 145177.31826716804 180438.29441496194 108374.9070214079 152909.26863728568 214858.76965806464 110935.06407207734 0.9917371198501421 0.570820752922659 1.7865068038698615 1.0595591288572452 1.3086693506828702 1.62652174877482 0.9769220212555514 1.3783673351280226 1.9367976343211506 1.0 16.759355915386294 -5.249408649706677 24.99497674885819 1.3775025657218822 0.7812789158031195 0.35861428022382724 0.3224114225434008 794.2621302155715 1650147.6322582804 0.07885330404379023 0.20518017688256682 5.631075500071185e-06 5.249408649706677 -0.5962236499187628 SDHYTIQR ddPTM_PC-9_AZD4547_30min_R2 2 SDHYTIQR 8 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;Q8WX93-4;Q8WX93-7;F8WA26 Q8WX93-3 PALLD Palladin 0 ; 109.01 0.0031766 1651400.0 10330.2 10540.0 45533.0 85658.0 62682.0 43520.0 21673.0 61267.0 32544.0 40316.0 False True 13614.98871849187 13946.848879066201 44929.2026692663 65910.87150290768 53979.68627007801 40798.68752022884 23601.855013835706 51799.59292560069 34264.209400107204 38904.54911123537 0.349958784500087 0.3584888964832764 1.1548573032116454 1.6941687542620323 1.387490345042684 1.0486868104698446 0.6066605462089689 1.3314533675096962 0.8807250098732524 1.0 15.24765123904112 -5.261065519568878 9.76532967734014 1.1566073920871889 0.3534585216039463 0.5544637663535439 0.2806413757538777 0.06826111688233798 169.58381888016345 0.07855835183473923 0.183527256288086 5.481942556941434e-06 5.261065519568878 -0.8031488704832426 SDHYTIQR ddPTM_PC-9_Lapatinib_30min_R1 2 SDHYTIQR 8 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;Q8WX93-4;Q8WX93-7;F8WA26 Q8WX93-3 PALLD Palladin 0 ; 96.492 0.0051225 1145300.0 14701.4 19489.3 38944.0 24149.0 35522.0 41925.0 26863.0 21197.8 41013.0 19898.1 False True 14491.75534009342 19444.173723269018 35742.17464818733 25924.99801870243 33432.665798939044 40131.96548194843 28253.83469833154 22182.727174373522 36393.68405396365 23337.460072448364 0.6209654047657925 0.8331743755707304 1.5315366169767406 1.1108748740531902 1.4325751686409454 1.7196372423290076 1.210664511503003 0.9505201982353645 1.5594535112640275 1.0 14.510359933727546 -5.102819235492051 4.551054817907931 1.318994270404287 0.6636909244657725 0.49761553964199035 0.23965968814288388 0.168966292945933 5.601874097562237 0.0616987474809437 0.1850397674430417 7.891885297847639e-06 5.102819235492051 -0.6553033459385145 SDIS(ph)PLTPR ddPTM_PC-9_AZD4547_30min_R2 3 SDISPLTPR 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.046)DIS(0.947)PLT(0.006)PR;S(0.076)DIS(0.924)PLTPR;S(0.003)DIS(0.996)PLT(0.001)PR 117.71 0.001842 134346800.0 87689.0 85420.0 92276.0 150161.0 140735.0 120941.0 102283.0 121157.0 106415.0 121695.0 True False 115572.27795549305 113030.34452085728 91052.3599479327 115543.70141432338 121196.37451292899 113378.54015128681 111385.9888515738 102434.9695608892 112039.87964947171 117434.49509107508 0.9841425031534575 0.9624969599707291 0.7753459482013185 0.9838991628883378 1.0320338535873674 0.9654619800030416 0.9484946375014393 0.8722732573716679 0.9540627697388264 1.0 16.84149672093436 SDIS(ph)PLTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDISPLTPR 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.225)DIS(0.772)PLT(0.003)PR 97.59700000000001 0.004732500000000001 14759000.0 35468.0 40176.0 39660.0 52929.0 53301.0 36958.0 55825.0 34006.0 45877.0 36209.0 True False 41472.03187506833 44164.407766065924 40605.64481138758 49963.55972813326 42857.051674430004 35019.85741915938 50536.851862000054 33113.37853233532 46547.864334243 42773.405069713735 0.969575178957009 1.0325202703428702 0.9493199043940258 1.1680987203777846 1.0019555750724063 0.8187297074451443 1.1815017247196746 0.774158112461841 1.0882431328152975 1.0 15.384426440204203 -6.526681529649936 24.999086068660493 0.9646801871287157 1.0319023017519224 0.04447307826588309 0.12263011141950646 341.481630095767 2244835.067184623 0.03796732043075491 0.03812983506844748 2.9738459687187434e-07 6.526681529649936 0.06722211462320671 SDIS(ph)PLTPR ddPTM_PC-9_Lapatinib_30min_R1 1 SDISPLTPR 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.007)DIS(0.993)PLTPR 103.26 0.0029146000000000003 15404000.0 45101.0 34250.0 46290.0 42111.0 41457.0 29731.0 28046.0 36321.0 39861.0 32573.0 True False 44457.85146948955 34170.69622931374 42484.21488456735 45207.98341817789 39018.58076759796 28459.474436346038 29498.08464986807 38008.60625632945 35371.43442506143 38203.19964920572 1.1637206275316228 0.8944459245058072 1.1120590755400415 1.1833559448761461 1.0213432677335756 0.7449500224502199 0.7721364943441684 0.9949063587693414 0.9258762289508081 1.0 15.221405853536348 -6.552620803784963 12.946281737991479 0.8803406738570627 1.0794976374534968 0.4461731065986386 0.10617930375723716 1.1588787137754601 502.44582534692466 0.03628373909579391 0.036321722361080395 2.8014262657626485e-07 6.552620803784963 0.1991569635964341 SDISPLT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 SDISPLTPR 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 SDISPLT(1)PR 100.88 0.0089935 214410000.0 55209.0 44854.0 61813.0 92224.0 74810.0 59171.0 70645.0 87860.0 76933.0 72270.0 True False 72764.31358146189 59352.178332223484 60993.3192321033 70963.18164659632 64423.922814596466 55471.028016072145 76932.26814250102 74283.2558219477 80999.52131816768 69739.8492972761 1.043367806421456 0.8510511412094729 0.8745834676543469 1.0175413678355625 0.9237749072267172 0.795399310079076 1.1031321248568549 1.0651479257619942 1.161452485692873 1.0 16.089695626108757 -7.28714161304813 24.870810296054444 1.087862159212343 0.9174593086259912 0.5164011982972587 0.07806452102303589 577.3608427546174 558681.6278123361 0.032167212986051054 0.021696432975981943 5.162480056908705e-08 7.28714161304813 -0.17040285058635174 SDISPLT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SDISPLTPR 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 SDIS(0.004)PLT(0.996)PR;S(0.006)DIS(0.006)PLT(0.988)PR;SDISPLT(1)PR 126.03 0.0034419000000000003 352648000.0 131509.0 116907.0 123542.0 153249.0 164345.0 154603.0 152745.0 191029.0 147358.0 126536.0 True False 153770.87627885328 128512.7543485533 126487.70981564412 144662.95536996133 132142.77701045378 146495.3465169731 138275.8878219653 186014.69116195597 149512.83197605328 149475.9751415749 1.028733053142557 0.8597552498107709 0.8462076243078017 0.9678007133450379 0.8840402404820967 0.9800594803159591 0.9250709867655887 1.2444454099448006 1.0002465736346158 1.0 17.18955409712504 -7.6671332086342465 14.542516966483156 1.0917330505973442 0.9234688720285037 0.4215293599923271 0.08242469709778365 0.7185574589243209 107.46250796085188 0.036717954452218544 0.02119594796168075 2.1521215256919274e-08 7.6671332086342465 -0.16826417856884046 SDISPLT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 SDISPLTPR 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 SDISPLT(1)PR;SDISPLT(1)PR;SDISPLT(1)PR 119.03 0.004308600000000001 496451000.0 175492.0 138038.0 158851.0 138526.0 168904.0 153857.0 155232.0 140228.0 189734.0 143383.0 True False 172989.45189870903 137718.3814920293 145790.88396259214 148713.6641491897 158969.3987980405 147276.89476818446 163269.1534039908 146743.5048074822 168364.15893240506 168166.56050416204 1.0286792533550546 0.8189403474695008 0.8669433657054779 0.8843236354679984 0.9453092120184385 0.8757799072933969 0.9708776400879647 0.8726081116694444 1.0011750161723627 1.0 17.35953133228316 -8.274049103679745 23.914807000512624 1.0005875624992402 0.9050852852476965 0.2964601286809553 0.056958874459045405 574.8435056264474 1090192.4094197026 0.05089050987949138 0.01354770541733097 5.320480996341391e-09 8.274049103679745 -0.0955022772515437 SDKNQQGFS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 SDKNQQGFSPK 11 1 D6RCT7;C9JKA9;Q9NS87-4;Q9NS87-2;Q9NS87 D6RCT7 KIF15 Kinesin-like protein;Kinesin-like protein KIF15 1 SDKNQQGFS(1)PK 62.035 0.026795 38685000.0 66295.0 48689.0 39851.0 62140.0 58569.0 50036.0 54752.0 52660.0 50403.0 58378.0 True False 87375.43097833711 64426.767084710984 39322.54970181917 47814.583053429706 50437.705324530136 46907.24101016013 59624.821931321574 44522.60700641673 53067.19968023609 56334.20398888028 1.5510191818026577 1.143652745984093 0.698022638423736 0.8487664627846299 0.8953300437951685 0.8326600482261021 1.0584124334674334 0.7903299213246179 0.9420067369854189 1.0 15.781723517514239 -4.894743662246146 3.136195665068844 0.8798815149771269 1.5778396733492632 0.8095249288724982 0.09973889039427071 0.1124185479506052 1.8900732053881097 0.02487935578276906 0.16893014228540623 1.2742549747035725e-05 4.894743662246146 0.6979581583721364 SDKNQQGFS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDKNQQGFSPK 11 1 D6RCT7;C9JKA9;Q9NS87-4;Q9NS87-2;Q9NS87 D6RCT7 KIF15 Kinesin-like protein;Kinesin-like protein KIF15 1 S(0.002)DKNQQGFS(0.998)PK 56.648 0.037599 9408100.0 50620.0 40884.0 33506.0 48398.0 42320.0 53883.0 57535.0 51512.0 48592.0 38416.0 True False 59188.966209427075 44942.69332705695 34304.910112212594 45686.41696843308 34027.699796661924 51057.280624399675 52084.86828267214 50159.864581475544 49302.566072967624 45380.51669911133 1.3042814519250758 0.9903521730491237 0.7559391696587795 1.0067407841860854 0.7498305940912364 1.1250925361411654 1.147736343065748 1.1053171764008982 1.0864258421705697 1.0 15.469785415069214 SDKNQQGFS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 SDKNQQGFSPK 11 1 D6RCT7;C9JKA9;Q9NS87-4;Q9NS87-2;Q9NS87 D6RCT7 KIF15 Kinesin-like protein;Kinesin-like protein KIF15 1 S(0.001)DKNQQGFS(0.999)PK;SDKNQQGFS(1)PK 64.842 0.021789 61943800.0 129397.0 89623.0 86010.0 87078.0 98065.0 89372.0 85635.0 85325.0 90154.0 68265.0 True False 127551.77505149666 89415.4834499206 78938.58980820126 93482.00660369263 92297.00950320812 85549.76789630762 90068.76128472689 89289.51099422696 79999.90715629289 80064.5142926051 1.593112456603981 1.1167929293012544 0.9859372845217168 1.1675835097438014 1.1527829815578214 1.06851042127922 1.1249523222680162 1.1152195424293467 0.9991930615344008 1.0 16.2888753413147 -4.763263248103536 5.381116026556971 1.0859715854552374 1.6187918581718916 0.8592263342286116 0.0622547025243444 0.05252859398320643 4.618920952421173 0.01526564437336851 0.10463529096016726 1.724792090340756e-05 4.763263248103536 0.5328202727166542 SDKS(ph)PDLAPTPAPQSTPR ddPTM_PC-9_AZD4547_30min_R2 6 SDKSPDLAPTPAPQSTPR 18 1 F8WAE5;Q9BY44-3;Q9BY44;Q9BY44-2;Q9BY44-4 F8WAE5 EIF2A Eukaryotic translation initiation factor 2A;Eukaryotic translation initiation factor 2A, N-terminally processed 1 S(0.003)DKS(0.997)PDLAPTPAPQSTPR;S(0.012)DKS(0.988)PDLAPTPAPQSTPR;S(0.423)DKS(0.577)PDLAPTPAPQSTPR;S(0.071)DKS(0.929)PDLAPTPAPQSTPR;S(0.002)DKS(0.997)PDLAPT(0.001)PAPQSTPR;S(0.056)DKS(0.944)PDLAPTPAPQSTPR 149.18 1.9853e-05 1264221000.0 445885.0 420233.0 464109.0 613037.0 562297.0 525108.0 515898.0 547686.0 498940.0 528308.0 True False 587667.15501585 556065.0991457894 457954.6114165665 471710.7909772347 484231.76750272966 492272.9137493639 561811.922573148 463053.7132722434 525312.9497938014 509812.0977244395 1.1527132401112463 1.0907255862067642 0.8982811774390205 0.9252640199844785 0.9498240031260765 0.9655967678025644 1.101998020605653 0.9082831014389351 1.0304050298895424 1.0 18.959606083026372 -5.073513254221874 5.066252528034409 0.9714193788692073 1.1400890213559765 0.5257555573305692 0.05797493859832362 0.14788062093790488 6.885955688493501 0.015057932305882012 0.044444824591667015 8.442804749422082e-06 5.073513254221874 0.1686696424867692 SDKS(ph)PDLAPTPAPQSTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 SDKSPDLAPTPAPQSTPR 18 1 F8WAE5;Q9BY44-3;Q9BY44;Q9BY44-2;Q9BY44-4 F8WAE5 EIF2A Eukaryotic translation initiation factor 2A;Eukaryotic translation initiation factor 2A, N-terminally processed 1 S(0.07)DKS(0.93)PDLAPTPAPQSTPR;S(0.182)DKS(0.818)PDLAPTPAPQSTPR;S(0.024)DKS(0.976)PDLAPTPAPQSTPR;S(0.001)DKS(0.999)PDLAPTPAPQSTPR;S(0.24)DKS(0.76)PDLAPTPAPQSTPR;S(0.001)DKS(0.999)PDLAPTPAPQSTPR;S(0.076)DKS(0.457)PDLAPT(0.112)PAPQS(0.177)T(0.177)PR 186.89 5.1651000000000006e-11 788242000.0 386141.0 380791.0 343114.0 447406.0 448229.0 374925.0 440097.0 394848.0 377593.0 309512.0 True False 451507.0446676086 418593.41391995235 351295.1390270906 422339.2923298224 360401.74508879863 355263.27298225847 398407.8261336426 384483.6583760376 383114.58328922617 365624.0755043565 1.2348941848120416 1.1448737705320085 0.9608096472927831 1.1551189339685322 0.9857166670210271 0.9716626906808423 1.0896651857076505 1.051581895545761 1.0478374072077792 1.0 18.480001546110564 -5.019160493772393 4.306707426247562 1.037254547095673 1.221884875846429 0.5761707266437368 0.05619959074661385 0.13051351230797537 5.847818222805766 0.014062028317308507 0.05101734932298297 9.568404050350819e-06 5.019160493772393 0.1846303287507558 SDKS(ph)PDLAPTPAPQSTPR ddPTM_PC-9_Lapatinib_30min_R1 5 SDKSPDLAPTPAPQSTPR 18 1 F8WAE5;Q9BY44-3;Q9BY44;Q9BY44-2;Q9BY44-4 F8WAE5 EIF2A Eukaryotic translation initiation factor 2A;Eukaryotic translation initiation factor 2A, N-terminally processed 1 S(0.008)DKS(0.992)PDLAPTPAPQSTPR;S(0.186)DKS(0.814)PDLAPTPAPQSTPR;S(0.189)DKS(0.811)PDLAPTPAPQSTPR;S(0.005)DKS(0.995)PDLAPTPAPQSTPR;S(0.227)DKS(0.773)PDLAPTPAPQSTPR 147.17 2.6696e-05 1118868600.0 674323.0 535986.0 538368.0 556745.0 561457.0 542698.2 507596.0 511585.0 548726.0 493599.3 True False 664707.030364306 534744.9573478806 494105.46120057727 597689.884546876 528433.2031269325 519488.2630772935 533876.8371936966 535355.1067328631 486922.69953905494 578917.281325275 1.148189995024226 0.9236983842039164 0.8534992427060669 1.03242709075574 0.9127956966791995 0.8973445427092196 0.9221988260076286 0.9247523333684425 0.8410920095948367 1.0 19.14299769769932 -4.761697252132469 8.204747731224632 0.9206669826765402 1.150684863889992 0.6009484848658417 0.055002670833667056 0.059402594967057 38.78813894915893 0.013155960209907478 0.07616291693089752 1.7310226393175455e-05 4.761697252132469 0.2300178812134518 SDLDYIRS(ph)PLPFQNR ddPTM_PC-9_AZD4547_30min_R2 1 SDLDYIRSPLPFQNR 15 1 H7BYL6;A0A0A0MRF6;Q99996-5;Q99996-3;Q99996;Q99996-1;Q99996-6 H7BYL6 AKAP9 A-kinase anchor protein 9 1 SDLDYIRS(1)PLPFQNR 105.58 0.0076208 0.0 3967.7 2023.8 6215.9 4088.4 6844.8 6925.5 3881.9 7026.0 3993.5 5277.8 True False 5229.346066713151 2677.953772433981 6133.473104603087 3145.8825451503376 5894.51766984828 6492.447390196343 4227.381579763248 5940.2931414182285 4204.588257108167 5093.025828437293 1.026766060661759 0.525808009352991 1.2042886313979362 0.617684388636921 1.1573704647119198 1.274772131322263 0.830033406891311 1.1663583381513902 0.8255580079000449 1.0 12.314307318305135 -5.26994135877443 24.982379539584574 1.0098005223071045 0.7762870240666883 0.14827132365894047 0.2235877897945491 1010.2121107803032 2968432.22642288 0.055747238494987736 0.11905093691734105 5.371043147425942e-06 5.26994135877443 -0.23351349824041623 SDLNGLPS(ph)PVEER ddPTM_PC-9_AZD4547_30min_R2 2 SDLNGLPSPVEER 13 0 E7EWN3;Q9C0A6 E7EWN3 SETD5 SET domain-containing protein 5 1 SDLNGLPS(1)PVEER;SDLNGLPS(1)PVEER 187.0 3.6824e-05 10478600.0 37791.0 33068.0 43541.0 55988.0 48153.0 46872.0 41272.0 43437.0 37022.0 45054.0 True False 49807.75189836849 43756.58432001525 42963.61789081598 43080.83160597715 41467.78713128275 43941.086430334704 44945.128045541795 36724.809732960945 38978.907338089026 43476.673173370305 1.1456201282870007 1.0064381914763523 0.9881992975748527 0.990895311473933 0.9537939337244872 1.0106818949810736 1.0337756954474364 0.8447014698322199 0.8965476080162411 1.0 15.40795392939241 -1.5228787452803376 0.6929183858211013 0.9537422443133577 22.579502672972588 0.5151948691213728 0.05302967410890665 245.8107393956201 1.3427037839708538 0.022710223305765956 8225.397618365785 0.029999999999999995 1.5228787452803376 21.62576042865923 SDLNGLPS(ph)PVEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SDLNGLPSPVEER 13 0 E7EWN3;Q9C0A6 E7EWN3 SETD5 SET domain-containing protein 5 1 SDLNGLPS(1)PVEER;SDLNGLPS(1)PVEER 167.18 0.00028702 9761700.0 33833.0 34313.0 36297.0 42077.0 43646.0 39622.0 39161.0 38086.0 35494.0 34989.0 True False 39560.25866779034 37719.36787328306 37162.458137139045 39719.562105474586 35093.87961543258 37544.152569455386 35451.386578912396 37086.282855452635 36013.03260194914 41332.228727228394 0.957128610916867 0.9125897401326125 0.8991157574006544 0.9609828293461603 0.8490681653543115 0.9083505469116515 0.857717758528664 0.8972727577843229 0.8713063319090961 1.0 15.334979538738027 -1.5228996353765478 0.6883208174846167 0.8964115690315737 7.5854118629053495 0.09198669130517245 0.043807624071107165 540.8955837296156 3.0075603293034208 0.01642811214455252 5556.627966156817 0.02999855699798161 1.5228996353765478 6.689000293873776 SDLNGLPS(ph)PVEER ddPTM_PC-9_Lapatinib_30min_R1 4 SDLNGLPSPVEER 13 0 E7EWN3;Q9C0A6 E7EWN3 SETD5 SET domain-containing protein 5 1 S(0.007)DLNGLPS(0.993)PVEER;SDLNGLPS(1)PVEER;SDLNGLPS(1)PVEER;SDLNGLPS(1)PVEER 177.66 8.198899999999999e-05 14761400.0 71659.0 63453.0 77990.0 66762.0 77114.0 71329.0 73003.0 71543.0 75025.0 63329.0 True False 70637.12951934886 63306.078477040704 71577.96325010585 71671.9001915032 72578.30613195714 68278.42494602021 76782.73813357767 74867.14896056206 66574.89445172556 74275.3332694118 0.9510173352320557 0.8523163167429574 0.9636841748050858 0.9649488872912166 0.9771522110671763 0.9192611051418702 1.033758244544942 1.007967863153217 0.8963257587851517 1.0 16.18059555291945 -5.406096337101139 7.635520106025524 0.9717374037014506 0.9019500315143149 0.28201364978809285 0.043989396391362894 0.3152428663708876 18.70687381781805 0.011216572562518854 0.023460704976847158 3.925578468425387e-06 5.406096337101139 -0.06978737218713571 SDLPGSDKDTEESGLHLS(ph)PTAAEAK ddPTM_PC-9_Lapatinib_30min_R1 1 SDLPGSDKDTEESGLHLSPTAAEAK 25 1 Q15599-2 Q15599-2 SLC9A3R2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 1 SDLPGS(0.003)DKDT(0.003)EES(0.013)GLHLS(0.78)PT(0.201)AAEAK 48.641000000000005 0.013534000000000001 7321800.0 33852.0 30179.0 31960.0 26956.0 36867.0 29034.0 30058.0 29604.0 30833.0 20856.0 True False 33369.264272303495 30109.12237969225 29332.37216916767 28938.434162579935 34698.55554331079 27792.283501559683 31614.256165076447 30979.50991471536 27360.26285411603 24460.93181112684 1.3641861450725443 1.2309065988236862 1.1991518718769698 1.1830470885584317 1.4185295887839822 1.136190710810022 1.292438751278301 1.2664893616449777 1.1185290513614177 1.0 14.57819174227355 -8.482568000608124 2.791392153274458 1.0011984929571973 1.2579656382503688 0.5317097700707851 0.07958195166792416 0.18770289609448532 3.287800075727939 0.0737046640734455 0.019842842444904637 3.2917890739085153e-09 8.482568000608124 0.25676714529317146 SDLYSSGR ddPTM_PC-9_AZD4547_30min_R2 1 SDLYSSGR 8 0 P38159;P38159-2;H3BUY5 P38159 RBMX RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed 0 93.195 0.034125 5521800.0 32926.0 28783.0 47894.0 62149.0 58680.0 43292.0 38213.0 46722.0 36660.0 45126.0 False True 43395.783096654806 38086.54186775735 47258.894266616306 47821.50824247828 50533.29489052964 40584.944396271734 41613.882971609986 39502.18846475127 38597.772757126666 43546.152475285395 0.9965468963368019 0.8746247303794141 1.0852599272332515 1.0981798740915025 1.1604537259453587 0.9319983991537647 0.95562709002197 0.9071338389119619 0.8863647087772638 1.0 15.410257634538016 -6.91150508286698 24.999910753118666 0.9315512930957185 1.0397872764590066 0.3318010604856164 0.07555739587166689 27.426496408842837 7741.293107729878 0.029214959697685616 0.02576517399072284 1.226012553669468e-07 6.91150508286698 0.1082359833632881 SDLYSSGR ddPTM_PC-9_Lapatinib_30min_R1 1 SDLYSSGR 8 0 P38159;P38159-2;H3BUY5 P38159 RBMX RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed 0 116.9 0.016447999999999997 13013000.0 57331.0 43669.0 48242.0 47801.0 55792.0 55219.0 45729.0 39525.0 47951.0 48192.0 False True 56513.44942678224 43567.88711351536 44275.728979505264 51316.44499946148 52510.424251292316 52857.41209177602 48096.62386628457 41361.4757931065 42550.25343358472 56521.92298819642 0.9998500836318688 0.7708139569599167 0.7833372723138143 0.9079033813159185 0.9290275609033714 0.9351665565733553 0.8509375004160541 0.7317775759636503 0.7528097273419125 1.0 15.786522929409921 -10.752133772363308 5.213541838673449 1.0000143980760487 0.8498186661972035 0.21303796629724936 0.08570226166554207 1.520708432208585e-05 2.248193176664722e-06 0.08798153069326452 0.02133661054859481 1.769563809337347e-11 10.752133772363308 -0.15019573187884527 SDPDGGDS(ph)PLPASGGPLTCK ddPTM_PC-9_AZD4547_30min_R2 2 SDPDGGDSPLPASGGPLTCK 20 0 Q8N1G0 Q8N1G0 ZNF687 Zinc finger protein 687 1 SDPDGGDS(0.997)PLPAS(0.003)GGPLTCK;SDPDGGDS(0.949)PLPAS(0.051)GGPLTCK 156.67 1.6935e-05 16135600.0 61515.0 71428.0 78749.0 83384.0 76265.0 74551.0 76154.0 89016.0 74566.0 74433.0 True False 81075.49040851353 94515.7041493301 77704.73680631752 64161.10706995777 65676.92117972461 69889.31418475593 82931.55847015374 75260.62258418517 78507.40653049383 71827.1233256421 1.1287587008175475 1.3158776207815668 1.08182999970677 0.8932712894413303 0.9143749344097444 0.9730212063192238 1.1545994692585355 1.0478022660461654 1.093005022275017 1.0 16.132241116330505 -5.477943534515645 6.976242654113593 1.0112494885964192 1.2182760144741582 0.4963054773329484 0.08428426287917555 0.20222015591210407 25.63708777540672 0.02394067630293051 0.04924356110700654 3.3270280736408695e-06 5.477943534515645 0.20702652587773906 SDPDGGDS(ph)PLPASGGPLTCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDPDGGDSPLPASGGPLTCK 20 0 Q8N1G0 Q8N1G0 ZNF687 Zinc finger protein 687 1 S(0.035)DPDGGDS(0.964)PLPASGGPLTCK 118.52 0.00036261 0.0 9655.3 12050.0 9095.3 11669.0 12098.0 10578.0 10465.0 8177.8 8633.5 9672.0 True False 11289.751589132382 13246.244364324339 9312.166446117337 11015.223761408439 9727.483746219667 10023.271058495258 9473.679439961143 7963.141415095324 8759.748604522678 11425.457036490128 0.9881225366368859 1.159362318900597 0.8150366691132394 0.9640948039302494 0.8513868386317022 0.8772752832979347 0.8291729083313268 0.696964803216448 0.7666869322204068 1.0 13.479964256087921 -5.513646616333619 0.751244180942411 0.8107644022321348 1.1074427544360905 0.3676383420180719 0.1015207798966482 1.1784974593843225 0.9734697114064599 0.04602595715555436 0.25101455044167803 3.064455954913132e-06 5.513646616333619 0.2966783522039558 SDPDGGDS(ph)PLPASGGPLTCK ddPTM_PC-9_Lapatinib_30min_R1 2 SDPDGGDSPLPASGGPLTCK 20 0 Q8N1G0 Q8N1G0 ZNF687 Zinc finger protein 687 1 SDPDGGDS(0.989)PLPAS(0.011)GGPLTCK;SDPDGGDS(1)PLPASGGPLTCK 279.5 7.180299999999999e-93 18728000.0 27560.0 62804.0 63087.0 59672.0 66932.0 65998.0 61085.0 70397.0 62154.0 51930.0 True False 27166.989346114977 62658.58119666629 57900.23038286239 64060.47793995661 62995.19135337494 63175.419388852264 64247.68240879954 73667.9016168835 55153.56200936423 60906.03130762453 0.4460476042003097 1.0287746525494326 0.9506485505584755 1.0517920239524323 1.0343013655773838 1.0372604819671387 1.0548656845542437 1.209533769238735 0.9055517298573322 1.0 15.89429747971315 -4.761204841954866 7.60619477155894 1.036711228026925 0.43694840431653215 0.8447867269065594 0.0750926555979033 0.035184405154861854 15.154448178241902 0.018222887715531693 0.10840968389585606 1.7329864141311502e-05 4.761204841954866 -0.5997628237103929 SDPES(ph)PIKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDPESPIKK 9 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1;H7C0Q4 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 S(0.022)DPES(0.978)PIKK 99.215 0.0061882 19439000.0 31612.0 23971.0 23474.0 35803.0 38604.0 34288.0 36895.0 41504.0 26520.0 25674.0 True False 36963.28723453988 26350.68246117997 24033.709185640735 33797.073984892115 31039.823321132742 32489.876919425744 33400.038503331714 40414.563977123 26907.804829089175 30328.492964727822 1.2187643902230274 0.8688424608445245 0.7924465357903556 1.1143670746910592 1.023454193956561 1.071265788155436 1.1012759038893265 1.3325609031785828 0.8872120635991732 1.0 14.888386191183443 -5.830024440440577 24.999999755188576 1.0882905881394611 0.9508850744728267 0.10987435828522274 0.14725198962668987 91.69653490302787 33422.9131537278 0.04100915149995003 0.06082643008065747 1.4790251519195335e-06 5.830024440440577 -0.13740551366663445 SDPGPPTETPS(ph)QRPSPLKR ddPTM_PC-9_Lapatinib_30min_R1 1 SDPGPPTETPSQRPSPLKR 19 2 P98174 P98174 FGD1 FYVE, RhoGEF and PH domain-containing protein 1 1 SDPGPPTET(0.001)PS(0.5)QRPS(0.5)PLKR 51.888000000000005 0.015719999999999998 4605000.0 52890.0 50648.0 49843.0 41910.0 51838.0 49340.0 38598.0 38481.0 48885.0 33955.0 True False 52135.778901161866 50530.72766780384 45745.10093954393 44992.201207661565 48788.99075742926 47229.84321715767 40596.41557853554 40268.96774179714 43379.05651812869 39824.07650780645 1.3091522383687173 1.2688486990501495 1.1486795162865062 1.1297738743255488 1.2251129225272928 1.185962045043267 1.019393772271849 1.0111714137025496 1.0892671047783211 1.0 15.281353286609374 -1.5228787452803376 0.17016391729103778 0.9634290345662017 2.3780411539811004 0.7398213431942742 0.05302143322072252 33.11388512218103 0.35866655638418576 0.15236115563684108 11.92526138922929 0.029999999999999995 1.5228787452803376 1.4146121194148988 SDPGPPTETPSQRPS(ph)PLKR ddPTM_PC-9_Lapatinib_30min_R1 1 SDPGPPTETPSQRPSPLKR 19 2 P98174 P98174 FGD1 FYVE, RhoGEF and PH domain-containing protein 1 1 SDPGPPTET(0.004)PS(0.239)QRPS(0.757)PLKR 54.236999999999995 0.010745999999999999 4443700.0 43178.0 37215.0 47547.0 40582.0 39551.0 40685.0 35714.0 34393.0 39661.0 32860.0 True False 42562.273802124575 37128.83095398278 43637.86919672764 43566.535657583416 37224.68794025781 38944.99739136724 37563.09617005592 35991.024337819406 35193.96053115482 38539.80721680227 1.1043717360259298 0.9633891198551626 1.1322804224537677 1.1304295170057217 0.9658763400359952 1.0105135495952433 0.9746570853026859 0.9338662265577793 0.9131846543282979 1.0 15.23406173457543 -6.280090877731282 23.945635584625364 0.9656665037485602 1.077648704809582 0.5489312629004841 0.05155224275541835 395.67711105391567 507986.6084740944 0.016749315685359194 0.01903154569179801 5.246976538311297e-07 6.280090877731282 0.11198220106102175 SDPVVSYR ddPTM_PC-9_Lapatinib_30min_R1 1 SDPVVSYR 8 0 P13639 P13639 EEF2 Elongation factor 2 0 104.21 0.017793 18352000.0 191400.0 180700.0 175910.0 173290.0 187720.0 174790.0 194470.0 166280.0 179900.0 159030.0 False True 188670.60090153856 180281.6002521745 161447.35883223682 186034.3246784937 176678.67867172003 167314.63915539076 204538.70505098207 174005.97583498404 159637.76756901623 186518.12360584494 1.0115403117621014 0.9665634457761884 0.8655853689232456 0.9974061559381027 0.9472467085562265 0.8970422601342726 1.0966157127079978 0.9329172547473086 0.8558834095198545 1.0 17.508956295619285 SDS(ph)ASSEPVGIYQGFEK ddPTM_PC-9_AZD4547_30min_R2 4 SDSASSEPVGIYQGFEK 17 0 Q05655;Q05655-2 Q05655 PRKCD Protein kinase C delta type;Protein kinase C delta type regulatory subunit;Protein kinase C delta type catalytic subunit 1 S(0.415)DS(0.585)AS(0.001)SEPVGIYQGFEK;S(0.001)DS(0.999)AS(0.001)SEPVGIYQGFEK;S(0.019)DS(0.975)AS(0.007)SEPVGIYQGFEK;S(0.102)DS(0.883)AS(0.014)SEPVGIYQGFEK 252.47 1.2490999999999996e-131 12033200.0 50802.2 70284.9 72625.9 76265.2 62716.0 70223.3 61064.9 87700.0 61181.0 59805.9 True False 66956.2428485962 93003.11942886912 71662.83311307996 58683.4364255942 54008.96595696073 65832.22594989162 66499.55780161382 74147.98014551375 64414.90275651298 57712.1136444992 1.160176583741845 1.611500836752557 1.241729484290175 1.016830483580592 0.9358341350942458 1.140700310430692 1.1522634262062275 1.2847905831738866 1.1161418060912183 1.0 15.816586548690571 -5.518541628343411 11.069473027606733 1.1042394146253525 1.3960933121274668 0.42887783522514944 0.13612506195448282 0.153427316674004 337.43336596823775 0.03669787963922538 0.06777675146859503 3.030109839346508e-06 5.518541628343411 0.2918538975021143 SDS(ph)ASSEPVGIYQGFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDSASSEPVGIYQGFEK 17 0 Q05655;Q05655-2 Q05655 PRKCD Protein kinase C delta type;Protein kinase C delta type regulatory subunit;Protein kinase C delta type catalytic subunit 1 S(0.005)DS(0.955)AS(0.04)SEPVGIYQGFEK 151.59 4.2374e-05 5428400.0 10379.0 11345.0 12458.0 10529.0 10672.0 9331.0 8178.6 7683.9 7007.9 6963.8 True False 12135.959705405847 12471.256623507024 12755.045967228096 9939.094265478563 8580.898209593008 8841.665933713291 7403.863800063661 7482.205766765022 7110.377279855738 8226.281814589527 1.4752667096673497 1.516025940345117 1.550523827740339 1.208212226312417 1.0431077372494775 1.0748070796738771 0.9000255482291786 0.9095489232444157 0.8643488565204874 1.0 13.006024780952915 -6.090351218110183 1.3657309618757831 0.9341793166105107 1.5349885191282915 0.9354215034482837 0.06453356215673602 0.09874997537821631 0.3724736769866801 0.024643121585629923 0.04079397371986866 8.121734380632705e-07 6.090351218110183 0.6008092025177808 SDS(ph)ASSEPVGIYQGFEK ddPTM_PC-9_Lapatinib_30min_R1 3 SDSASSEPVGIYQGFEK 17 0 Q05655;Q05655-2 Q05655 PRKCD Protein kinase C delta type;Protein kinase C delta type regulatory subunit;Protein kinase C delta type catalytic subunit 1 S(0.07)DS(0.93)AS(0.001)SEPVGIYQGFEK;S(0.016)DS(0.967)AS(0.017)SEPVGIYQGFEK;S(0.006)DS(0.991)AS(0.002)SEPVGIYQGFEK 224.64 6.476199999999999e-29 15666600.0 51999.4 75850.0 71996.3 59604.0 69213.0 74088.0 82318.0 83626.0 80817.0 69186.0 True False 51257.879020477936 75674.3739852102 66077.04212775492 63987.47699311529 65142.0274179935 70919.42894756328 86580.02325493262 87511.5692517223 71714.53841926168 81144.70791544992 0.6316848052973083 0.932585450477687 0.8143111710575752 0.7885600754122882 0.802788365272931 0.8739871122767361 1.0669829922260132 1.0784630507624287 0.8837857731151837 1.0 16.308209387901307 -7.06737850058739 3.8392987888758503 1.0128209955375216 0.8041539516471526 0.5850777872677135 0.08431387685026004 0.16913484270325604 4.853556526095639 0.032398565897016 0.025329509617834676 8.562912365928704e-08 7.06737850058739 -0.20866704389036894 SDS(ph)DSSTLAK ddPTM_PC-9_Lapatinib_30min_R1 1 SDSDSSTLAK 10 0 Q6AWC2-2;Q6AWC2-4;Q6AWC2;Q6AWC2-6;Q6AWC2-3;Q6AWC2-7 Q6AWC2-2 WWC2 Protein WWC2 1 S(0.006)DS(0.986)DS(0.004)S(0.004)T(0.001)LAK 110.08 0.0017916 3855200.0 16982.0 22853.0 16254.0 17608.0 19360.0 17582.0 22127.0 19055.0 18927.0 15695.0 True False 16739.833565882618 22800.08528258412 14917.65886225442 18902.9510585661 18221.282863224464 16830.058845643813 23272.62779175751 19940.36486369753 16795.241949854186 18407.859837727065 0.9093851057891145 1.2386059804657548 0.8103961565200835 1.0268956426876057 0.9898642766651118 0.9142865598721295 1.26427667294924 1.0832527539583707 0.912395145221184 1.0 14.16803428320747 SDS(ph)DSSTLPR ddPTM_PC-9_Lapatinib_30min_R1 1 SDSDSSTLPR 10 0 Q9ULE0 Q9ULE0 WWC3 Protein WWC3 1 SDS(1)DSSTLPR 125.23 0.00038651 10657000.0 19378.0 22227.0 27242.0 14505.0 20654.0 21557.0 16864.0 21288.0 25812.0 14061.0 True False 19101.66616651001 22175.53474712282 25002.26791716102 15571.746087261532 19439.172327326356 20635.05736182139 17737.135403814264 22277.118195664796 22904.78074759003 16491.425114895213 1.1582786832204819 1.3446706147362404 1.5160768546666554 0.9442328955062217 1.1787442378020265 1.251259804295725 1.0755368490133648 1.3508303885480393 1.3888903225775322 1.0 14.009428454938174 -5.746210724476118 24.99998496169546 1.184368891093954 1.3401747759067444 0.19640937218821486 0.15543300619800582 445.4187974977884 731211.7457715296 0.04297321652531214 0.07407310227589757 1.7938630135002063e-06 5.746210724476118 0.15580588481279034 SDS(ph)DSSTLSK ddPTM_PC-9_AZD4547_30min_R2 1 SDSDSSTLSK 10 0 H0YBE8;H3BLZ3;Q8IX03;Q8IX03-2;H0YAU4 H0YBE8 WWC1 Protein KIBRA 1 S(0.002)DS(0.998)DSSTLSK 84.289 0.032099 0.0 18063.0 19949.0 31905.0 38620.0 30724.0 33411.0 22349.0 30725.0 25951.0 31802.0 True False 23806.658266259958 26397.124126042836 31481.918853643318 29716.75567305204 26458.50293484377 31321.804888289655 24338.01770425019 25977.157240261186 27322.71687998347 30688.621659775436 0.7757486970313858 0.8601599778149175 1.025849880214975 0.9683313901322179 0.862160028826703 1.0206325078895333 0.7930632393357312 0.8464752027071415 0.8903207574094549 1.0 14.905416230004809 -4.942223507513146 4.593920987499775 0.9197483988429077 0.7848759866346625 0.2774850353557493 0.07493994400362998 0.2900953218779772 12.334946867705446 0.01945773471037891 0.08769651643938392 1.1422903094166708e-05 4.942223507513146 -0.1348724122082452 SDS(ph)DSSTLSK ddPTM_PC-9_Lapatinib_30min_R1 1 SDSDSSTLSK 10 0 H0YBE8;H3BLZ3;Q8IX03;Q8IX03-2;H0YAU4 H0YBE8 WWC1 Protein KIBRA 1 SDS(0.99)DS(0.002)S(0.002)T(0.002)LS(0.004)K 80.737 0.017245 6267400.0 41287.0 62275.0 56606.0 42517.0 63847.0 47842.0 44864.0 46183.0 56792.0 46004.0 True False 40698.23980889147 62130.80606366461 51952.07318547889 45643.84201255422 60091.64498803161 45795.90918514908 47186.83839876208 48328.83077933051 50395.48691372741 53955.73010352319 0.7542894838195131 1.1515145091069319 0.9628647983411597 0.8459498541670883 1.1137212835918564 0.8487682234543373 0.8745473058788409 0.8957126645604364 0.9340154755951805 1.0 15.719488561745672 SDS(ph)FENPVLQQHFR ddPTM_PC-9_AZD4547_30min_R2 4 SDSFENPVLQQHFR 14 0 P12956;B1AHC9;P12956-2 P12956 XRCC6 X-ray repair cross-complementing protein 6 1 S(0.138)DS(0.862)FENPVLQQHFR;S(0.479)DS(0.521)FENPVLQQHFR;S(0.207)DS(0.793)FENPVLQQHFR;S(0.204)DS(0.796)FENPVLQQHFR 215.15 1.3812e-15 24290200.0 37754.5 46456.9 63647.0 103599.0 120312.0 97480.0 52685.1 91843.0 79350.0 57668.3 True False 49759.64565761566 61473.1844108055 62802.999193788964 79715.85113859457 103608.75553628818 91384.56019007113 57373.97183543742 77650.77469218252 83544.27900376428 55649.35036986444 0.8941639988049491 1.1046523275156652 1.1285486492902244 1.4324668771293108 1.861814286198658 1.6421496312661041 1.030990864297796 1.3953581520015805 1.5012624307112428 1.0 15.76407722572144 -5.647589285566312 3.2436271898430973 1.439130909917391 1.0180840306819665 0.3197730129557991 0.24666582368898787 0.2923905610390384 6.044409772934143 0.0731535977723819 0.1373072718025228 2.2511825539168567e-06 5.647589285566312 -0.4210468792354245 SDS(ph)FENPVLQQHFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SDSFENPVLQQHFR 14 0 P12956;B1AHC9;P12956-2 P12956 XRCC6 X-ray repair cross-complementing protein 6 1 S(0.148)DS(0.852)FENPVLQQHFR;S(0.06)DS(0.94)FENPVLQQHFR;S(0.126)DS(0.874)FENPVLQQHFR 185.63 3.2268e-06 12981600.0 46271.7 51268.0 71026.0 80215.0 117742.0 102792.0 79385.0 101902.0 74133.0 68636.0 True False 54104.584902266826 56357.54822159169 72719.52920760504 75720.813610539 94671.30031801907 97401.40656502594 71865.07810237118 99227.18047409362 75217.05487914287 81079.16347772299 0.6673056625347695 0.6950928673194351 0.8968954055327074 0.9339121219639096 1.1676403191311984 1.2013124258711376 0.8863569259951302 1.2238308366533273 0.9276989506657802 1.0 16.307043583638347 -5.523581819638139 1.511038278427974 1.0728516475999221 0.6549770173938438 0.6492303666514068 0.10913117969101753 0.26060273131660533 1.1193112869645687 0.03301176110972477 0.10569093392519614 2.995147263472984e-06 5.523581819638139 -0.4178746302060783 SDS(ph)FENPVLQQHFR ddPTM_PC-9_Lapatinib_30min_R1 4 SDSFENPVLQQHFR 14 0 P12956;B1AHC9;P12956-2 P12956 XRCC6 X-ray repair cross-complementing protein 6 1 S(0.166)DS(0.834)FENPVLQQHFR;S(0.125)DS(0.875)FENPVLQQHFR;S(0.183)DS(0.817)FENPVLQQHFR;S(0.171)DS(0.829)FENPVLQQHFR 152.94 0.00014626 20647300.0 56213.4 37696.7 79402.4 43792.3 83460.6 54160.0 59579.4 71985.2 79515.2 72098.9 True False 55411.78660772498 37609.41560722835 72874.24117412776 47012.931828830304 78551.61159785294 51843.7030531264 62664.12980775687 75329.89518689258 70559.36084382348 84561.09879925457 0.655286974679348 0.4447602519512186 0.8617939242621356 0.5559640602641357 0.928933194024974 0.6130916436670454 0.7410515082889305 0.8908339207573853 0.8344186847823397 1.0 16.367706502981683 -4.632560393966411 0.10222421773898227 1.1935887666119476 1.4143685346591873e-16 0.4351988118240704 0.12853693132318883 52.47149819066724 0.8311796497083146 2.1410146477420953 9.492416499256013 2.3304490152720863e-05 4.632560393966411 -1.1935887666119473 SDS(ph)FPGSHR ddPTM_PC-9_AZD4547_30min_R2 1 SDSFPGSHR 9 0 A0A2R8YF49;A0A2R8YFR7;Q12774 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 S(0.173)DS(0.827)FPGSHR 75.566 0.014613999999999999 10343000.0 63502.0 61673.0 98410.0 168070.0 102130.0 99967.0 105490.0 188870.0 139800.0 125070.0 True False 83694.31507634616 81607.5911687523 97105.01910004832 129324.0581556151 87951.01239212339 93716.04768691894 114878.40563879126 159684.4813008338 147189.5425926434 120691.33736834514 0.6934575165151617 0.6761677594116734 0.8045732296733749 1.071527260990764 0.7287268026842757 0.7764935722014689 0.9518363798404765 1.3230815465527832 1.2195534973933284 1.0 16.880962604678672 -7.563750640230434 4.31169670384101 1.2009918093694008 0.8002678627544464 0.6480357942782922 0.12774559990503384 0.13052254780248052 5.379407880978358 0.0653058857427111 0.03717747729488769 2.730545135602289e-08 7.563750640230434 -0.40072394661495436 SDS(ph)FPGSHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDSFPGSHR 9 0 A0A2R8YF49;A0A2R8YFR7;Q12774 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 S(0.123)DS(0.877)FPGSHR 75.695 0.014506999999999999 8335700.0 58339.0 56903.0 42412.0 59732.0 79819.0 73567.0 73066.0 98893.0 78580.0 68090.0 True False 68214.64045222763 62551.95378117411 43423.2629284057 56385.40969375682 64179.0399354858 69709.01701269804 66144.65952796942 96297.16353579452 79729.08384124536 80434.17799985655 0.8480802831397032 0.7776787845247286 0.5398608403567342 0.7010130655385995 0.7979075752548905 0.8666591584092818 0.8223451917179707 1.1972169782846076 0.9912338986218963 1.0 16.29552103957772 -7.293423372817084 1.3012364381708854 1.0647719197870142 0.7199498448827094 0.6175935994333313 0.10534502305751815 0.2949887154136698 0.969412947753709 0.069881402835752 0.039306713102427795 5.0883459080995286e-08 7.293423372817084 -0.34482207490430483 SDS(ph)FPGSHR ddPTM_PC-9_Lapatinib_30min_R1 1 SDSFPGSHR 9 0 A0A2R8YF49;A0A2R8YFR7;Q12774 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 S(0.028)DS(0.971)FPGSHR 71.555 0.019645 10281000.0 31345.0 36425.0 36399.0 25698.0 44514.0 38723.0 47033.0 42839.0 47901.0 44383.0 True False 30898.014552031014 36340.66015044534 33406.41472420323 27587.916646014957 41895.7740378912 37066.90755772185 49468.13860576355 44829.456331458285 42505.88496010807 52054.54241336987 0.5935699963831602 0.69812658925826 0.641757917280683 0.5299809654830273 0.8048437676234484 0.7120782517569774 0.9503135809538492 0.861201621473559 0.8165643763144619 1.0 15.667736441850403 -6.826980238969641 1.3704085697980193 0.8962447967396272 0.6277143586726868 0.7057643395269424 0.07860219256261484 0.23831838167625138 0.9328001163388927 0.03715123143580182 0.03167081300630758 1.4894288473471692e-07 6.826980238969641 -0.26853043806694044 SDS(ph)GGSSSEPFDR ddPTM_PC-9_AZD4547_30min_R2 1 SDSGGSSSEPFDR 13 0 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 S(0.12)DS(0.87)GGS(0.008)SS(0.001)EPFDR 103.14 0.0015742 18246000.0 12104.0 8516.0 13466.0 25205.0 18859.0 16355.0 14859.0 15023.0 9938.2 13178.0 True False 15952.82022115987 11268.630460543432 13287.432041471908 19394.37666336812 16240.753380035749 15332.319264552896 16181.422214302804 12701.540544196692 10463.512962762587 12716.642231071019 1.2544836861244537 0.8861325384314416 1.0448852613786883 1.5251177402774734 1.2771259177484875 1.2056892838497022 1.2724602863141157 0.9988124469808998 0.8228204248128266 1.0 13.634430163687847 -7.907826983010697 4.701211968548263 0.9105938881993962 1.2044997231237733 0.37629006420377387 0.16077903021750675 0.2391839117982489 9.053792872665602 0.10186085528087949 0.046479553262533314 1.2364399161121225e-08 7.907826983010697 0.29390583492437705 SDS(ph)GGSSSEPFDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDSGGSSSEPFDR 13 0 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 S(0.326)DS(0.511)GGS(0.055)S(0.018)S(0.09)EPFDR 84.734 0.008440799999999998 10977000.0 5773.1 10705.0 12084.0 11616.0 20784.0 16121.0 15637.0 14051.0 15491.0 12346.0 True False 6750.371806077505 11767.721653119668 12372.128388825195 10965.193179580117 16711.524399192374 15275.586380601451 14155.750157923778 13682.176138265113 15717.52656890727 14584.232069117781 0.46285411354441264 0.8068797587250347 0.8483222380301577 0.751852626015119 1.1458624849078718 1.047404231378601 0.9706201938392549 0.9381485479264432 1.077706833957288 1.0 13.832121802861788 -4.478761341754786 0.6853674032566701 1.0168660857790155 5.861939487948914e-19 0.7502233799989929 0.09407731143337532 2.3569692015859993 0.6275225051183648 0.04160244780437289 2.0468508365357816 3.3207689394109245e-05 4.478761341754786 -1.0168660857790155 down SDS(ph)GGSSSEPFDR ddPTM_PC-9_Lapatinib_30min_R1 1 SDSGGSSSEPFDR 13 0 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 S(0.132)DS(0.868)GGSSSEPFDR 176.99 0.00014412 12277000.0 19472.0 16988.0 29011.0 20211.0 34901.0 27308.0 24770.0 30394.0 34937.0 30298.0 True False 19194.325709272543 16948.66532973961 26625.827565698473 21697.38436191954 32848.19179800605 26140.100498057163 26052.469399459176 31806.216198752158 31002.027157080138 35534.96893045269 0.5401531586207023 0.4769573701586939 0.7492852355607583 0.6105924675039003 0.9243906154046436 0.7356162474552121 0.733150194965635 0.8950680739584079 0.8724371538851151 1.0 15.116951817447275 -4.3559570963512195 0.22908808959052027 0.9876947203090207 5.254042389982832e-14 0.7171715027094221 0.08695149529496156 7.695807480196612 0.30268680880279414 0.14281660289895454 2.228245716334122 4.405983877638935e-05 4.3559570963512195 -0.9876947203089682 SDS(ph)LGTQGR ddPTM_PC-9_AZD4547_30min_R2 2 SDSLGTQGR 9 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 S(0.015)DS(0.985)LGTQGR;S(0.001)DS(0.994)LGT(0.004)QGR 119.03 0.00041230000000000005 0.0 172600.0 176504.0 208618.0 359890.0 271870.0 262520.0 228149.0 253120.0 198588.0 232062.0 True False 227483.209696976 233555.46627615724 205851.58901142047 276922.9207450722 234125.54331779605 246104.5829000565 248453.81901682256 214006.12011895538 209084.95625456295 223937.58001417492 1.0158331160074903 1.042948960426265 0.9192364631179383 1.2366076329285303 1.0454946566046497 1.0989874182103712 1.1094780027590536 0.9556507670816533 0.9336751618077153 1.0 17.772737128356084 -7.774658295033536 24.904524471769864 0.9584971588788366 1.0672705318096092 0.27527913132821447 0.07709398929912505 299.2456010225081 563771.9847362008 0.04207771294562574 0.020407040374214924 1.680125428896429e-08 7.774658295033536 0.1087733729307726 SDS(ph)LGTQGR ddPTM_PC-9_Lapatinib_30min_R1 1 SDSLGTQGR 9 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 S(0.011)DS(0.95)LGT(0.039)QGR 94.82 0.010158 0.0 117900.0 121930.0 146690.0 106170.0 95537.0 134930.0 122820.0 96718.0 146450.0 101430.0 True False 116218.72437978801 121647.67857635708 134629.7144397752 113978.09597273752 89917.70149296871 129159.35843719267 129179.01863712452 101211.87136641816 129955.25881313182 118962.04035302045 0.9769395685792573 1.02257558978786 1.1317031385832057 0.958104750343109 0.755852045124121 1.085719092022225 1.085884356503849 0.850791320206609 1.0924094646282876 1.0 16.86014177123989 -4.4190180485932 16.774520993452757 0.9946085680225198 0.0010571649233145392 0.002340929435463046 0.11172473421671851 16781653.73068581 20965468.395499956 0.028294309228584242 627663129.7457814 3.8104998722867265e-05 4.4190180485932 -0.9935514030992053 SDS(ph)LLSFR ddPTM_PC-9_AZD4547_30min_R2 2 SDSLLSFR 8 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 S(0.128)DS(0.872)LLSFR;S(0.129)DS(0.871)LLSFR 163.88 8.3336e-05 37233000.0 53520.0 53624.0 65592.0 71117.0 76740.0 80156.0 66583.0 85467.0 75264.0 72233.0 True False 70538.2467148444 70956.90932552618 64722.20722294856 54722.07439669713 66085.97562882135 75143.8326487008 72508.75801163753 72260.03898627816 79242.30138549872 69704.14465601409 1.011966319405346 1.0179725994156361 0.9285273858871506 0.7850619883042449 0.9480924836672454 1.0780396634881793 1.0402359625738762 1.0366677525831105 1.1368377271761225 1.0 16.08895682182539 -6.719224526539517 6.599509304260298 1.0595228739648854 0.9328820504560085 0.437180924631939 0.06802486692529841 0.19910445083565975 22.116844976527823 0.02466808653457962 0.024320993998330688 1.9088661359251922e-07 6.719224526539517 -0.12664082350887695 SDS(ph)LLSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SDSLLSFR 8 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 SDS(0.999)LLSFR;S(0.143)DS(0.857)LLSFR;S(0.006)DS(0.994)LLSFR 139.38 0.0027427 33894300.0 26097.9 32516.1 35798.0 39880.0 44736.0 37560.5 33714.2 30603.6 32000.9 28981.7 True False 30515.759012979208 35744.08351658145 36651.560084671015 37645.65289270445 35970.30194006304 35590.76125851874 30520.546906329444 29800.287927194513 32468.85262274512 34235.85279098905 0.8913392401608592 1.0440541304696045 1.0705607454392896 1.099597346750272 1.050661777279592 1.0395757183500423 0.8914790904335972 0.8704409412298331 0.9483874352705183 1.0 15.063220328944812 -7.254110610811841 24.09832345401612 0.9167802773081615 1.0387382302605006 0.4086823745191127 0.061095105357382704 308.98307781594923 1015994.8103767165 0.024160457773373036 0.01830331844178974 5.570438569142446e-08 7.254110610811841 0.12195795295233913 SDS(ph)LLSFR ddPTM_PC-9_Lapatinib_30min_R1 2 SDSLLSFR 8 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 S(0.486)DS(0.514)LLSFR;S(0.366)DS(0.634)LLSFR 130.98 0.0037311999999999996 32218000.0 31143.0 30975.0 40759.0 33977.0 40556.0 40151.0 35398.1 38950.0 41805.0 37740.0 True False 30698.89510907325 30903.279290598315 37407.95235428992 36475.781923949355 38170.5758161638 38433.8353265524 37230.84041376649 40759.759193965816 37096.48067383389 44263.308714611 0.6935517474982562 0.6981692103012029 0.8451232734425437 0.8240636089617259 0.8623525200583112 0.8683000987195896 0.8411219471597445 0.9208475456899433 0.8380864818085461 1.0 15.433823677225801 -2.550995758210856 0.2268995530647138 0.9492868771563923 2.0085642130687865e-33 0.7714016876611505 0.04148304491931764 15.415102135027626 0.3003652298182624 0.06302837684817442 4.913119367002843 0.0028119282945946937 2.550995758210856 -0.9492868771563923 SDS(ph)PEIPFQAAAGPSDGLDASSPGNSFVGLR ddPTM_PC-9_AZD4547_30min_R2 1 SDSPEIPFQAAAGPSDGLDASSPGNSFVGLR 31 0 Q12888;Q12888-3;Q12888-2;A6NNK5 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 S(0.265)DS(0.735)PEIPFQAAAGPSDGLDASSPGNSFVGLR 87.73899999999999 3.1559e-09 1670300.0 4150.9 3136.4 7403.5 6795.5 5467.3 6779.6 6323.6 8325.7 6771.0 5515.3 True False 5470.799855916427 4150.179964355141 7305.324752639033 5228.902464428408 4708.259767467496 6355.670540260647 6886.388149563583 7039.154370553048 7128.901236729531 5322.211025726669 1.0279186280798536 0.7797849322948438 1.3726108786980313 0.9824680831242462 0.8846435710099739 1.1941786053838168 1.2938961112732936 1.3225996369792488 1.339462340420105 1.0 12.377809999030797 -6.936414564849341 6.503656463175032 1.2630612271253712 1.0160378694528491 0.3000666821042405 0.16767865083076555 0.24795103088905227 19.60847549285048 0.05923793890508923 0.05205871861176618 1.1576717488525719e-07 6.936414564849341 -0.24702335767252204 SDS(ph)PESDAEREK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDSPESDAEREK 12 1 O75400-2;O75400-3;O75400 O75400-2 PRPF40A Pre-mRNA-processing factor 40 homolog A 1 S(0.019)DS(0.665)PES(0.317)DAEREK 126.32 0.001289 13205000.0 46187.0 41295.0 40463.0 44628.0 44065.0 36863.0 45113.0 41644.0 36118.0 32099.0 True False 54005.5468651681 45394.49469085259 41427.79137678202 42127.63784592817 35430.77957324926 34929.83938639731 40839.57005016408 40550.88912546528 36646.15742145715 37918.29460445582 1.4242609650177107 1.1971660425233954 1.09255418285383 1.1110108797186704 0.9343980245642627 0.9211869824518075 1.0770413193995538 1.0694280834217713 0.9664505696717389 1.0 15.210606459265009 -4.201028162701369 0.8187967348223008 1.003415479628138 2.1868959595261988 0.8456191529004017 0.055454256771048184 2.236511622363353 0.590707008609689 0.02170926482530093 3.0023654344093584 6.29465362583016e-05 4.201028162701369 1.1834804798980607 SDS(ph)QASLTVPLSPQVVR ddPTM_PC-9_AZD4547_30min_R2 1 SDSQASLTVPLSPQVVR 17 0 Q8TEV9-2;Q8TEV9 Q8TEV9-2 SMCR8 Smith-Magenis syndrome chromosomal region candidate gene 8 protein 1 S(0.03)DS(0.963)QAS(0.004)LT(0.001)VPLS(0.003)PQVVR 73.735 0.010262 3323300.0 10357.0 8511.0 10803.0 12693.0 10403.0 6675.7 6860.1 9191.2 6278.4 8408.7 True False 13650.310561017244 11262.014308323756 10659.7451614452 9766.82495489512 8958.723018851046 6258.26742368547 7470.635610225368 7770.91123276448 6610.26340639236 8114.313972409084 1.68225072476023 1.387919465110387 1.313696413238542 1.2036538132619752 1.1040641327551763 0.7712626655765741 0.9206737175351605 0.9576793872147086 0.814642301107535 1.0 12.986253411420469 -5.459407332021646 0.6732903224692982 0.8795469442157795 1.7764241958521743 0.8886820002700618 0.09001093424333478 0.4828323026981439 0.29609123743695054 0.04696923499366152 0.29276893844257096 3.472103543079102e-06 5.459407332021646 0.8968772516363948 SDS(ph)QASLTVPLSPQVVR ddPTM_PC-9_Lapatinib_30min_R1 1 SDSQASLTVPLSPQVVR 17 0 Q8TEV9-2;Q8TEV9 Q8TEV9-2 SMCR8 Smith-Magenis syndrome chromosomal region candidate gene 8 protein 1 S(0.003)DS(0.968)QAS(0.027)LT(0.001)VPLSPQVVR 96.012 0.0015937999999999998 2478700.0 8079.0 7714.5 10877.0 6553.8 7666.7 7269.1 6341.0 7065.1 9258.2 6445.1 True False 7963.7919784928545 7696.637549227469 9982.735046434202 7035.788314835892 7215.7597793121395 6958.217538099733 6669.305953248717 7393.370338415608 8215.44402283194 7559.126947444073 1.0535333027031129 1.0181913338325257 1.3206201080945743 0.9307673179393905 0.9545758166889848 0.9205054481129568 0.8822852162184911 0.9780719902998174 1.0868244547222194 1.0 12.884003902530818 SDS(ph)RAQAVSEDAGGNEGR ddPTM_PC-9_AZD4547_30min_R2 2 SDSRAQAVSEDAGGNEGR 18 1 P55884;P55884-2;C9JZG1 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 1 S(0.221)DS(0.778)RAQAVS(0.001)EDAGGNEGR;SDS(1)RAQAVSEDAGGNEGR 139.81 0.00068659 37179000.0 12384.599999999999 5377.299999999999 18384.0 48433.0 29975.0 21073.8 16756.7 18494.9 13142.5 19611.9 True False 16322.64518431728 7115.407066167238 18140.216148107786 37267.52013239072 25813.488656162674 19756.05195459094 18248.01383797079 15636.938175521771 13837.185719054472 18925.293350397784 0.8624777900192602 0.37597340946990826 0.958517039194349 1.9691911476557062 1.3639676901293638 1.0438967359084923 0.964212997923609 0.8262454846013314 0.7311477535836259 1.0 14.2080280423435 -7.443599383453614 2.5980591465792138 0.8374791737064621 1.1091945126918188 0.07518401012792997 0.38305662766933146 0.894431717375332 11.8288590243551 0.22531905393595705 0.13148650872536022 3.600813403627814e-08 7.443599383453614 0.2717153389853567 SDS(ph)RAQAVSEDAGGNEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SDSRAQAVSEDAGGNEGR 18 1 P55884;P55884-2;C9JZG1 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 1 S(0.081)DS(0.916)RAQAVS(0.002)EDAGGNEGR;S(0.075)DS(0.924)RAQAVSEDAGGNEGR 137.89 0.00053429 21100100.0 12613.3 4918.5 4031.0 25266.0 16693.9 22779.4 12951.9 40492.0 25147.0 13890.2 True False 14748.482565969305 5406.776174765916 4127.11432765263 23850.4279334772 13422.850133163867 21584.80816315816 11725.002268364331 39429.12790482038 25514.72730155 16408.383305237305 0.8988382518624985 0.3295130345376656 0.25152473896287625 1.4535513639460451 0.8180483039349464 1.3154743987647228 0.714573888862158 2.402986764225285 1.5549811841247083 1.0 14.002145478704737 -6.541028475668326 0.7454246519680721 1.5838868268754531 0.5089132414975289 0.3253938774962002 0.496998036911505 0.7525400442115154 0.9312835946969676 0.3254854785726698 0.41026006218814015 2.8772097566702275e-07 6.541028475668326 -1.0749735853779243 SDS(ph)RAQAVSEDAGGNEGR ddPTM_PC-9_Lapatinib_30min_R1 1 SDSRAQAVSEDAGGNEGR 18 1 P55884;P55884-2;C9JZG1 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 1 SDS(0.998)RAQAVS(0.002)EDAGGNEGR 83.792 0.032407 0.0 12810.0 2839.6 7098.4 7765.7 4015.3 6354.8 4136.5 4107.1 7460.1 4379.7 True False 12627.327050933702 2833.025080664504 6514.796952616391 8336.815483615783 3779.1279483835324 6083.020017762331 4350.667729950056 4297.930859705699 6619.86497966435 5136.725309416579 2.458244560554065 0.5515235699816454 1.2682782434703193 1.6229825387650842 0.7357076192989498 1.1842213961901014 0.8469730164419086 0.8367063840900324 1.2887325252780986 1.0 12.32663321111348 -4.7487013153560085 24.99545489305329 1.046882678843852 2.4582478831673087 0.6719546457835178 0.2977931405714736 369.0001440746213 724032.7495812745 0.07345048715506486 1.3036337117479635 1.7836050143827794e-05 4.7487013153560085 1.4113652043234566 SDS(ph)SADCQWLDTLR ddPTM_PC-9_Lapatinib_30min_R1 1 SDSSADCQWLDTLR 14 0 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 S(0.084)DS(0.535)S(0.381)ADCQWLDTLR 85.619 0.029186 0.0 4441.6 4723.8 5644.9 4581.1 5225.9 4412.4 3930.2 5707.5 5455.5 5547.4 True False 4378.261969510318 4712.862331329409 5180.798111944135 4918.009376101607 4918.522836514706 4223.691937806777 4133.686525383706 5972.691286253138 4841.044141038176 6506.260698554133 0.6729306082806189 0.7243580529099817 0.7962788999671421 0.7558887668295433 0.7559676847267639 0.6491734858926564 0.635339823733519 0.9179913875231638 0.7440593553396941 1.0 12.667612915368213 -8.849753209523762 0.8414488046304487 0.9982100492185794 0.7242503735888104 0.5348902096978287 0.07488498100513526 0.9097984602640368 1.1950581540080394 0.07522068304961782 0.02564527389342394 1.4133404557669216e-09 8.849753209523762 -0.273959675629769 SDS(ph)VSASER ddPTM_PC-9_AZD4547_30min_R2 1 SDSVSASER 9 0 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 S(0.019)DS(0.917)VS(0.061)AS(0.003)ER 70.41199999999999 0.037743 103800000.0 22071.0 21089.0 28329.0 40224.0 31485.0 32338.0 37739.0 33738.0 32270.0 38619.0 True False 29089.11889468105 27905.60683212778 27953.33895016023 30950.978254605016 27113.85122065993 30315.899747912677 41097.697889869676 28524.567322113307 33975.72631948929 37266.96056470874 0.7805605408622461 0.7488028647700875 0.7500836807343937 0.8305205948004017 0.7275573540155122 0.8134792665818148 1.1027917830462566 0.7654116914789572 0.9116849296173566 1.0 15.185609539452463 -7.017078614845458 24.596272545818994 0.9300962948097116 0.7691509270019917 0.5053704610800057 0.08280960140248127 532.3690881675831 766705.76447152 0.03017657581285754 0.02397022021995214 9.614382256106433e-08 7.017078614845458 -0.16094536780771984 SDS(ph)VSASER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SDSVSASER 9 0 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 S(0.48)DS(0.518)VS(0.003)ASER;S(0.019)DS(0.955)VS(0.027)ASER;SDS(0.507)VS(0.491)AS(0.002)ER 131.42 0.0012343 118319400.0 239185.4 245094.8 218712.0 230563.7 268774.0 277314.0 299434.0 323933.0 248474.8 218946.5 True False 279674.7640930131 269426.1919688968 223926.92354987905 217645.96338660142 216109.66411030313 262771.16565660393 271069.4438055729 315430.1019853844 252108.27388186217 258639.7672704591 1.0813293216451039 1.041704432432304 0.8657869047481748 0.8415023168459994 0.8355623978130079 1.0159735621081991 1.0480578708614292 1.2195730970308978 0.9747467550812983 1.0 17.980584588846476 -6.9930872643908355 4.96427792907339 1.0740551397204274 0.9293993834744315 0.2756434793767788 0.09680351194320182 0.23804287496334578 16.76219144562628 0.038655925830103764 0.03234205669518227 1.0160445147892799e-07 6.9930872643908355 -0.14465575624599591 SDS(ph)VSASER ddPTM_PC-9_Lapatinib_30min_R1 1 SDSVSASER 9 0 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 S(0.076)DS(0.903)VS(0.022)ASER 129.0 0.001312 87138000.0 75911.0 89566.0 73192.0 68736.0 115930.0 79193.0 131050.0 89120.0 126800.0 89177.0 True False 74828.49521962757 89358.61542991863 67174.43628929036 73791.07473657413 109111.22532714947 75806.09999789955 137835.12776742532 93260.84054855557 112518.44873680508 104591.1256291165 0.7154382818765315 0.8543613513328765 0.6422575135819177 0.7055194625043013 1.0432168567920512 0.7247852008659934 1.317847254615015 0.8916706841769876 1.075793458192611 1.0 16.674400921107654 -6.594491005370926 1.3267795773151025 1.0427203178854718 0.7343757278463914 0.43191768071221204 0.152073564303071 0.40625695914517895 1.4911783873027264 0.0647812839655462 0.06794390268349763 2.5439524801266274e-07 6.594491005370926 -0.30834459003908044 SDS(ph)YSQSLK ddPTM_PC-9_AZD4547_30min_R2 2 SDSYSQSLK 9 0 Q9H8W4 Q9H8W4 PLEKHF2 Pleckstrin homology domain-containing family F member 2 1 S(0.351)DS(0.643)YS(0.006)QSLK;S(0.004)DS(0.989)YS(0.006)QS(0.001)LK 90.61399999999999 0.008437700000000001 32299000.0 66080.0 60669.0 89444.0 114164.0 117113.0 110139.0 85477.0 110027.0 81680.0 94688.0 True False 87092.06545061478 80279.06780304245 88257.9141183285 87845.25361621745 100853.88146752909 103251.99091889875 93084.28740910949 93024.85531893285 85997.43804697515 91373.00194078391 0.9531487813769819 0.8785863011819278 0.9659080061255488 0.9613917869651181 1.1037601843582796 1.1300054581309833 1.018728567869912 1.0180781340556093 0.9411690129509753 1.0 16.479480333455683 -6.059648536671539 4.909210036555789 1.040212377702305 0.9317500304687977 0.4341145585320638 0.05388469411582014 0.2070372268318703 10.248676718969321 0.017350300954573586 0.02322984766666627 8.716687236214937e-07 6.059648536671539 -0.10846234723350723 SDS(ph)YSQSLK ddPTM_PC-9_Lapatinib_30min_R1 2 SDSYSQSLK 9 0 Q9H8W4 Q9H8W4 PLEKHF2 Pleckstrin homology domain-containing family F member 2 1 S(0.006)DS(0.994)YSQSLK;S(0.062)DS(0.899)YS(0.039)QSLK 112.94 0.0021347 32485000.0 70632.0 84398.0 92207.0 91157.0 136060.0 168661.0 176776.0 161460.0 215910.0 181809.0 True False 69624.7747276774 84202.58161639747 84626.09638931291 97860.98987083766 128057.21830425218 161447.76219799384 185928.59630838915 168962.02103870874 191591.94216690527 213234.44340473553 0.32651748758770727 0.39488264781208177 0.3968687939813082 0.45893612827403263 0.6005465920962386 0.7571373537039392 0.871944482043561 0.7923767771326029 0.8985037272015614 1.0 17.702080967485628 -6.594808273346552 0.7769826429036119 0.9213619679299269 0.3315298265938912 0.9660215468643759 0.042756179183532854 0.11230074228878817 0.1506584848573243 0.02811514972859896 0.03273915609939376 2.5420947086248117e-07 6.594808273346552 -0.5898321413360357 down SDS(ph)YVELSQYR ddPTM_PC-9_AZD4547_30min_R2 1 SDSYVELSQYR 11 0 P52298-3;P52298;F8WE41 P52298-3 NCBP2 Nuclear cap-binding protein subunit 2 1 S(0.122)DS(0.876)YVELS(0.001)QYR 129.76 0.00024321 6495100.0 11919.0 14387.0 14951.0 16156.0 20590.0 17959.0 13583.0 26485.0 22511.0 19509.0 True False 15708.994069398903 19037.316396880953 14752.739971190138 12431.483807711771 17731.433909270698 16836.020890987813 14791.860686242342 22392.351814754013 23700.885502882662 18825.995848077448 0.8344309749225373 1.0112249333585763 0.7836366315090163 0.660336053828531 0.9418590151809404 0.8942964306829562 0.785714647214953 1.1894378387978222 1.2589445835505721 1.0 14.200438561423178 -7.765807035735005 24.99845982530938 1.1681435098073432 0.8471480328385866 0.6221381078006342 0.10860623587322603 70.88054107709232 405676.3539336399 0.05782125537715163 0.029291245907633927 1.7147190164679526e-08 7.765807035735005 -0.3209954769687565 SDSAS(ph)SEPVGIYQGFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDSASSEPVGIYQGFEK 17 0 Q05655;Q05655-2 Q05655 PRKCD Protein kinase C delta type;Protein kinase C delta type regulatory subunit;Protein kinase C delta type catalytic subunit 1 SDS(0.005)AS(0.987)S(0.008)EPVGIYQGFEK 160.03 2.9506999999999997e-05 4799000.0 20460.0 22959.0 19726.0 18395.0 18546.0 17840.0 18440.0 11261.0 15428.0 17827.0 True False 23923.47389657997 25238.217789254984 20196.342651271603 17364.387787394648 14912.044433574953 16904.438994474884 16693.22970596115 10965.41068201576 15653.605313091552 21058.893981545658 1.1360270827871872 1.1984588464793904 0.9590409956463086 0.8245631419490225 0.7081114728362603 0.8027220712202926 0.7926926134197632 0.5207021171968943 0.7433251398107198 1.0 14.362142047193213 -5.580396261656258 1.8190726260633774 0.7412132879246539 1.1785525663530534 0.6604057354462487 0.11364227209017573 0.20155742586802539 1.3158657302026935 0.033731459534168694 0.08646014866298447 2.6278691610567128e-06 5.580396261656258 0.4373392784283995 SDSDLLTCS(ph)PTEDATMGSR ddPTM_PC-9_AZD4547_30min_R2 2 SDSDLLTCSPTEDATMGSR 19 0 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 SDSDLLT(0.055)CS(0.935)PT(0.01)EDATMGSR;SDSDLLT(0.157)CS(0.796)PT(0.042)EDAT(0.005)MGSR 119.08 4.6013e-05 6298600.0 36351.0 34929.0 34133.0 44147.0 35673.0 37537.0 21242.3 32018.0 20643.9 27630.0 True False 47909.86185222922 46219.11617617679 33680.374117893974 33969.591214350825 30720.41971080204 35189.805456039256 23132.82354821216 27070.353800445322 21735.094408642854 26662.682109917474 1.7968883120880261 1.7334758740938927 1.2632027782893678 1.2740500402139012 1.152187900082837 1.319814912504621 0.867610522184025 1.0152899730359914 0.8151878464079294 1.0 14.70253429396162 -3.560908858031206 0.3440253939389256 0.8983142636709571 3.8633680552243748 0.8494833590852608 0.1223179807244886 5.423865538113354 0.26639272867294256 0.11117187485606637 7.883449891557662 0.0002748470892562035 3.560908858031206 2.9650537915534176 SDSDYDLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 SDSDYDLSPK 10 0 A0A1B0GW84;A0A1W2PQN6;E9PMG3;A0A087WSZ7;Q08499-2;Q08499-10;Q08499-9;Q07343-3;Q07343;Q08499-11;Q08499;Q08499-7;Q08499-12;Q08499-6 A0A1B0GW84;Q08499-7 PDE4B;PDE4D cAMP-specific 3,5-cyclic phosphodiesterase 4D;cAMP-specific 3,5-cyclic phosphodiesterase 4B 1 SDS(0.002)DYDLS(0.998)PK 104.43 0.0026051 6372700.0 49776.0 47044.0 38665.0 43301.0 36267.0 37450.0 39864.0 38771.0 32083.0 36023.0 True False 49066.18511219955 46935.07250837477 35486.11295121615 46485.499987901516 34133.846363665376 35848.35080021389 41927.96286394998 40572.442200494195 28469.474691032472 42249.52755236968 1.1613428114996174 1.1109017124557714 0.8399173909632468 1.1002608237519629 0.8079107232940144 0.8484911637361787 0.9923889163489199 0.9603052282703829 0.673841255520399 1.0 15.366647588360502 -4.56555740285406 0.8109120881552365 0.8913583357311169 1.4430462853767023 0.37432637934109003 0.11636226010995315 3.599139791622388 1.4353993671865575 0.042325669747410415 1.9394047600668907 2.719209051008465e-05 4.56555740285406 0.5516879496455854 SDSFENPVLQQHFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SDSFENPVLQQHFR 14 0 P12956;B1AHC9;P12956-2 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 ; 171.99 1.5597000000000004e-19 10142000.0 64804.0 68834.0 83004.0 87531.0 84549.0 88106.0 75396.0 75785.0 84978.0 64924.0 False True 75774.03726265735 75667.38461194206 84983.13015442314 82626.92184933083 67982.23039007476 83485.56625825136 68253.94506023015 73795.72405084489 86220.6424874188 76694.2072618988 0.9880020925687488 0.9866114705840782 1.1080775613759062 1.0773554457271164 0.8864063247687796 1.088551133635962 0.8899491564878366 0.9622072733452209 1.124213230250737 1.0 16.226829994172924 SDSFENPVLQQHFR ddPTM_PC-9_Lapatinib_30min_R1 3 SDSFENPVLQQHFR 14 0 P12956;B1AHC9;P12956-2 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 ;; 137.09 5.519e-05 23942100.0 204750.0 169001.0 219799.0 186304.0 185961.0 226913.0 190215.0 162248.0 214542.0 147914.0 False True 201830.22745344858 168609.68856789044 201727.9746686766 200005.4176519255 175023.139593393 217208.45995003846 200063.401970857 169786.63439544442 190378.0207325841 173480.73781698427 1.1634157774125446 0.9719216708990908 1.1628263587482093 1.1528969738584105 1.0088909108631754 1.252060964711744 1.1532312145335493 0.9787059735390508 1.0974014932621847 1.0 17.40441595857385 -7.754763283733556 24.999920503384324 1.02854029623514 1.120935713904888 0.23526030851296476 0.08100422627168616 241.05221088246907 902675.5050832814 0.03900548758562467 0.021850824105640897 1.7588820478326495e-08 7.754763283733556 0.09239541766974813 SDSLLS(ph)FR ddPTM_PC-9_AZD4547_30min_R2 2 SDSLLSFR 8 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 S(0.001)DS(0.005)LLS(0.994)FR;SDSLLS(1)FR 102.06 0.010971 0.0 10523.3 11782.4 13409.7 15116.1 13169.7 14335.400000000001 14615.2 16637.0 12879.5 13237.2 True False 13869.490501762355 15590.830382610013 13231.878616257667 11631.316686416938 11341.314480569321 13439.005171817285 15915.92448660598 14066.133930227013 13560.284075979618 12773.7696570901 1.0857789731681966 1.2205347991347486 1.035863255050422 0.910562582437124 0.8878596361939489 1.052078245700786 1.245984929575728 1.1011732877474885 1.061572616385247 1.0 13.640896720020011 -10.044611281395138 15.431889730216351 0.9999991482523637 1.0664200503535681 0.033778135539568654 0.10719875538957341 0.0 0.0 0.11672194897435263 0.028309230849953588 9.023784570079581e-11 10.044611281395138 0.06642090210120444 SDSLLS(ph)FR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SDSLLSFR 8 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 S(0.048)DS(0.006)LLS(0.946)FR;S(0.039)DS(0.012)LLS(0.949)FR;S(0.192)DS(0.004)LLS(0.804)FR 129.42 0.0037852 4961870.0 13250.300000000001 16200.9 19860.0 19821.5 20983.8 20948.899999999998 15272.5 18579.800000000003 17637.800000000003 12585.500000000002 True False 15493.314084645825 17809.21828398193 20333.537719469434 18710.965617170044 16872.175023468677 19850.30280556922 13825.77823667525 18092.099936925355 17895.719457560677 14867.151523236824 1.042117184346331 1.1978904133819286 1.3676821472955896 1.2585440854574919 1.1348626532189487 1.3351786167339392 0.9299547539463802 1.2169177067071693 1.2037086882171282 1.0 13.859840639787523 -7.239796934638731 24.98492089617409 1.1057217078275858 1.2258092873257525 0.23254644426206628 0.11831812986138239 1377.5734026444106 1590328.926887864 0.0456676844651957 0.035342234536997176 5.7570906173644484e-08 7.239796934638731 0.12008757949816662 SDSLLS(ph)FR ddPTM_PC-9_Lapatinib_30min_R1 1 SDSLLSFR 8 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 SDS(0.004)LLS(0.996)FR 104.42 0.0038583 2736200.0 5561.4 6028.3 9008.1 7361.0 8306.4 6371.7 5618.0 5666.6 8360.4 4263.8 True False 5482.093416164147 6014.341841727646 8267.488790271573 7902.352495576155 7817.833883010732 6099.1972441581565 5908.872550914879 5929.8909229403525 7418.763713085063 5000.792148843623 1.09624500539016 1.2026778283753294 1.653235836283125 1.5802201452030924 1.5633191003186402 1.2196462205629817 1.1815873115784745 1.1857903201019009 1.4835177092494372 1.0 12.287940927287213 -6.788181949117463 24.296768896529773 1.2236874686205927 1.4290681848339504 0.2178442992516646 0.19336960453866864 281.79644553435594 256021.63167340876 0.07298026823092517 0.06438293339081294 1.62861357661713e-07 6.788181949117463 0.20538071621335763 SDSLS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 2 SDSLSPPR 8 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 SDS(0.007)LS(0.993)PPR;SDS(0.011)LS(0.989)PPR 128.28 7.491899999999999e-05 32421000.0 239850.0 226330.0 264360.0 271790.0 289340.0 294610.0 250810.0 278660.0 246570.0 283380.0 True False 316117.3108100789 299486.74637562153 260854.41367024434 209133.01461364093 249170.1353719474 276187.99012717354 273131.604116649 235599.49996976994 259603.18681736832 273458.9524541597 1.1559954719824728 1.0951798933180839 0.9539070172294752 0.7647693108482093 0.911179294500209 1.0099796976786537 0.9988029342810946 0.8615534355536004 0.9493314608556689 1.0 18.060964768020852 -5.223411097733301 3.43342333651827 0.9234715822161219 1.1401087540332686 0.5556176425432138 0.07042821596514634 0.1803033146561325 4.382428771760474 0.019795359960792028 0.05879726833098369 5.9784541412929845e-06 5.223411097733301 0.2166371718171467 SDSLS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SDSLSPPR 8 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 SDS(0.077)LS(0.923)PPR;S(0.004)DS(0.009)LS(0.987)PPR 99.788 0.0050921000000000004 27924000.0 362260.0 405540.0 452490.0 390130.0 469290.0 435280.0 422090.0 340780.0 342150.0 331900.0 True False 423583.46303885867 445799.3310795106 463279.07767788036 368272.2809185254 377335.9933264524 412453.15053335327 382106.57953303296 331834.8860862559 347153.29646579374 392070.84268104594 1.0803748122209857 1.1370377047960525 1.181620837984025 0.9393003529673821 0.9624178904663397 1.0519862882761943 0.9745855542843337 0.8463646105818874 0.885435127212984 1.0 18.580754830691824 -5.7685446548944475 24.994960533276508 0.9506509695952633 1.1334137841484437 0.6717787921179549 0.05815779448782165 100.72888473156281 354345.42889884213 0.01809063227385391 0.027488853046529527 1.7039441078877857e-06 5.7685446548944475 0.18276281455318044 SDSLS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 2 SDSLSPPR 8 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 S(0.001)DS(0.03)LS(0.969)PPR;SDS(0.031)LS(0.969)PPR 94.40899999999999 0.0067423000000000005 57037000.0 225340.0 279940.0 279150.0 243004.0 335620.0 292880.0 264110.0 282630.0 297780.0 266899.0 True False 222126.6102777052 279291.81612946186 256199.36455016173 260875.32479757993 315879.4914543075 280354.205136626 277784.3234998452 295762.02159154223 264240.8806375853 313032.1365294372 0.7095968252346405 0.8922145158192011 0.8184442894286319 0.8333819258619394 1.0090960466757142 0.8956083814425291 0.8873987398853621 0.9448295784280573 0.8441333965490038 1.0 18.25595124926786 -3.461314524882675 0.5866185590072612 0.9207722844762417 1.8653499407950452e-13 0.4875089036694872 0.06069495711211328 14.136407383182279 1.1094194045855104 0.028297437171771016 12.46917358136437 0.00034568893220382723 3.461314524882675 -0.9207722844760552 SDSPES(ph)DAEREK ddPTM_PC-9_AZD4547_30min_R2 1 SDSPESDAEREK 12 1 O75400-2;O75400-3;O75400 O75400-2 PRPF40A Pre-mRNA-processing factor 40 homolog A 1 SDS(0.003)PES(0.997)DAEREK 101.45 0.013109 23268000.0 13573.0 13214.0 21159.0 23370.0 21674.0 23451.0 22801.0 19668.0 15689.0 19947.0 True False 17888.931664061696 17485.167086146186 20878.41783495501 17982.407562900724 18664.939220472726 21984.60526279608 24830.244828610143 16628.762525678 16518.288510271686 19248.661601394284 0.9293597671625078 0.9083835254748123 1.0846685482507872 0.9342159956512592 0.9696746509960321 1.1421368258250026 1.2899725364184051 0.8638918834997593 0.8581525745704407 1.0 14.232470515322735 -6.577733650800437 24.999791909349565 1.0404521945769272 0.9666754706384865 0.060966893815564416 0.1258608901742218 286.9424750388481 130769.99232181524 0.045141926730960395 0.04514193132877459 2.64402982171328e-07 6.577733650800437 -0.0737767239384407 SDSPES(ph)DAEREK ddPTM_PC-9_Lapatinib_30min_R1 1 SDSPESDAEREK 12 1 O75400-2;O75400-3;O75400 O75400-2 PRPF40A Pre-mRNA-processing factor 40 homolog A 1 SDS(0.019)PES(0.981)DAEREK 146.84 0.00061889 35748000.0 50338.0 79200.0 82844.0 75894.0 111870.0 73840.0 77710.0 71589.0 80221.0 77616.0 True False 49620.17088914135 79016.61726603347 76032.88610708802 81475.49793496229 105290.02654488219 70682.03532944716 81733.44356204974 74915.28628849333 71185.66621541987 91031.82218318112 0.5450859897025008 0.8680109369559829 0.8352341443203114 0.8950221579769229 1.156628792215206 0.776454141357463 0.8978557344219642 0.8229571208378441 0.7819866120242511 1.0 16.474083338932815 -4.746034494088028 3.9213111263123377 0.8926045744224803 0.4980996566159488 0.48666538567534134 0.10734958843440649 0.25896793354646996 6.999698769850182 0.027440854689621996 0.3077301478345823 1.7945910847468486e-05 4.746034494088028 -0.3945049178065315 SDSQAS(ph)LTVPLSPQVVR ddPTM_PC-9_Lapatinib_30min_R1 1 SDSQASLTVPLSPQVVR 17 0 Q8TEV9-2;Q8TEV9 Q8TEV9-2 SMCR8 Smith-Magenis syndrome chromosomal region candidate gene 8 protein 1 SDS(0.396)QAS(0.603)LTVPLSPQVVR 171.25 2.0884999999999997e-24 0.0 8756.1 8039.5 7570.0 6354.1 6401.9 9204.4 6448.5 7425.9 8115.9 5002.7 True False 8631.236408327917 8020.88503169541 6947.623821045037 6821.401710656221 6025.352828619663 8810.749268504373 6782.371777247176 7770.934423580761 7201.801877784199 5867.4100293212605 1.4710470829880582 1.3670230973483308 1.1841040231252997 1.1625916164998815 1.0269186572114637 1.5016419893060715 1.1559396298117175 1.3244232778597373 1.2274243391538293 1.0 12.518508099340279 -14.442529870278003 0.18337837145253824 2.5624851892778385e-17 1.3133966338621508 0.26279821932963165 0.13961269994228723 206.70224717936387 2.049865987996615 76.2812042207939 0.43089362270561526 3.609691856846585e-15 14.442529870278003 1.3133966338621508 SDSQASLT(ph)VPLSPQVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDSQASLTVPLSPQVVR 17 0 Q8TEV9-2;Q8TEV9 Q8TEV9-2 SMCR8 Smith-Magenis syndrome chromosomal region candidate gene 8 protein 1 SDS(0.003)QAS(0.302)LT(0.465)VPLS(0.23)PQVVR 142.84 0.00027529 9286000.0 9475.6 10002.0 14225.0 14574.0 21701.0 12725.0 15166.0 14624.0 14004.0 14375.0 True False 11079.631928369172 10994.932459084821 14564.17794861292 13757.466029545501 17448.84483193195 12057.678598917773 13729.366687668477 14240.135495408802 14208.782007034884 16981.073707562617 0.6524694562414387 0.6474815814613752 0.8576712049796169 0.8101646731218496 1.0275466164522336 0.7100657359226831 0.8085099284124788 0.8385886393665953 0.8367422609270534 1.0 14.05164006244526 -5.260932137100181 24.849192183135813 0.8522408169610696 0.649975498741766 0.4789791436664691 0.08770972718823462 33.826077820449214 1656979.3117476315 0.022080209671954915 0.05166466512087562 5.483626454290849e-06 5.260932137100181 -0.2022653182193036 SDSQASLTVPLS(ph)PQVVR ddPTM_PC-9_AZD4547_30min_R2 4 SDSQASLTVPLSPQVVR 17 0 Q8TEV9-2;Q8TEV9 Q8TEV9-2 SMCR8 Smith-Magenis syndrome chromosomal region candidate gene 8 protein 1 SDSQASLTVPLS(1)PQVVR;SDSQAS(0.035)LT(0.073)VPLS(0.892)PQVVR;SDSQASLT(0.014)VPLS(0.986)PQVVR;SDS(0.001)QAS(0.023)LT(0.016)VPLS(0.96)PQVVR 231.4 1.0865e-29 32150500.0 41803.399999999994 40980.2 73432.0 99877.0 97786.0 67976.0 70326.0 113256.0 69592.0 74130.0 True False 55096.01163526386 54226.248238511245 72458.24370038355 76851.90073426778 84210.101809225 63725.449974151576 76584.87776048573 95754.88756397148 73270.49104511614 71534.73126341599 0.7701994634240116 0.7580408464642324 1.0129099868086016 1.074329900692184 1.1771918384530424 0.890832311083858 1.0705971268484022 1.3385789793683347 1.0242645740194154 1.0 16.12635624319907 -5.352739407491109 2.837543218140092 1.0908607102445902 0.7542939526660374 0.5592877794567614 0.11092638374274534 0.1961107854571105 3.0184015305072807 0.03132372910211624 0.08295538095946334 4.438749051520479e-06 5.352739407491109 -0.3365667575785528 SDSQASLTVPLS(ph)PQVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SDSQASLTVPLSPQVVR 17 0 Q8TEV9-2;Q8TEV9 Q8TEV9-2 SMCR8 Smith-Magenis syndrome chromosomal region candidate gene 8 protein 1 SDSQASLTVPLS(1)PQVVR;SDSQASLT(0.001)VPLS(0.999)PQVVR;SDSQASLTVPLS(1)PQVVR 206.45 2.5651999999999996e-17 26000100.0 25985.4 26436.4 34278.3 36439.1 42657.6 37706.8 39591.9 41566.4 34725.2 29867.1 True False 30384.21498495549 29060.831079919015 35095.62467317669 34397.53536415617 34299.14950014382 35729.38902897232 35841.46861146655 40475.32604324124 35232.99035637587 35281.768802166494 0.8611874068822121 0.8236784057758045 0.9947240703822543 0.9749379504477669 0.9721493752897578 1.0126870120745857 1.0158637117214397 1.1472022922148912 0.9986174603074994 1.0 15.10663526975742 -5.114050115588653 0.584281197770123 1.0476832784370707 0.7379155090718676 0.6423858186124063 0.05000248134756398 1.6304738896137019 0.5533580524529625 0.027939362854495334 0.32399775013895027 7.690416912868524e-06 5.114050115588653 -0.309767769365203 SDSQASLTVPLS(ph)PQVVR ddPTM_PC-9_Lapatinib_30min_R1 4 SDSQASLTVPLSPQVVR 17 0 Q8TEV9-2;Q8TEV9 Q8TEV9-2 SMCR8 Smith-Magenis syndrome chromosomal region candidate gene 8 protein 1 SDSQASLTVPLS(1)PQVVR;SDSQASLTVPLS(1)PQVVR;SDSQASLTVPLS(1)PQVVR;SDSQAS(0.001)LT(0.001)VPLS(0.998)PQVVR 192.72 1.4809e-09 33590800.0 124109.0 99217.0 119492.0 106967.0 104950.0 112114.0 87660.0 97481.0 103611.0 86318.0 True False 122339.18290119687 98987.26913237423 109667.82901245895 114833.71001145142 98777.04733963877 107319.14557049883 92198.60587632576 102010.32313188669 91941.23810780069 101237.9512884945 1.2084320291366908 0.9777683948808232 1.0832679604503463 1.1342950795617497 0.975691883157108 1.0600683262018504 0.9107118891964772 1.0076292717657944 0.9081696827882138 1.0 16.627390692056963 -6.682315889548647 1.201442450475295 0.9590189051220063 1.0909924587305813 0.41772573443745786 0.06930578277625163 0.46930585064696484 1.4322839916780725 0.03230665901495501 0.03140844818038109 2.0781845435903473e-07 6.682315889548647 0.131973553608575 SDSSPLPS(ph)EK ddPTM_PC-9_AZD4547_30min_R2 1 SDSSPLPSEK 10 0 O14646;O14646-2;A0A087WVF4 O14646 CHD1 Chromodomain-helicase-DNA-binding protein 1 1 SDSSPLPS(1)EK 79.07 0.019530000000000002 2134800.0 12959.0 11915.0 7593.8 14102.0 10871.0 12359.0 9577.6 11979.0 9072.4 11008.0 True False 17079.692436055077 15766.290739475693 7493.101250299224 10851.001773728116 9361.749297119079 11586.189776252477 10429.987845730297 10127.920800035436 9551.948542328313 10622.613270574431 1.6078616439296836 1.4842195924753938 0.7053915133158214 1.0215002181983166 0.8813037864281423 1.0907099299517227 0.9818664748553236 0.9534302475352899 0.8992089139485147 1.0 13.374851106963863 -5.154776439173383 5.738059367204875 0.9484642011637144 1.5726725982827856 0.8555192499689093 0.09963354025726157 0.0725197749689705 3.245716419749533 0.024651513045432914 0.06815586498835566 7.002023448856695e-06 5.154776439173383 0.6242083971190712 SDSVLPASHGHLPQAGS(ph)LER ddPTM_PC-9_AZD4547_30min_R2 4 SDSVLPASHGHLPQAGSLER 20 0 Q8N4C8;Q8N4C8-4;Q8N4C8-3;Q8N4C8-2;Q8N4C8-5 Q8N4C8;Q8N4C8-3 MINK1 Misshapen-like kinase 1 1 SDSVLPASHGHLPQAGS(1)LER;SDSVLPASHGHLPQAGS(1)LER;SDSVLPASHGHLPQAGS(1)LER;SDSVLPASHGHLPQAGS(1)LER 113.67 1.9417e-05 66735500.0 81734.0 77089.0 290929.0 571890.0 429455.0 349519.0 205920.0 433137.0 265375.0 341107.0 True False 107723.7118271875 102006.51169244148 287071.09137036855 440049.5961124221 369832.5861828976 327663.5216769959 224246.48108010224 366205.6291480887 279402.18072619993 329164.94775489054 0.3272636183224555 0.3098948183522859 0.872119262176522 1.336866513624351 1.123547901152251 0.9954386817668913 0.6812586899352515 1.1125292399626345 0.8488211841263671 1.0 18.328451188104495 -5.318842309791304 4.109686112431891 1.0137783485128191 0.31000649644580425 0.7352120137778062 0.1641174849056219 0.10662884445785797 3.691974482290254 0.04617002791772086 0.1081743668496301 4.799076691400328e-06 5.318842309791304 -0.7037718520670149 down SDSVLPASHGHLPQAGS(ph)LER ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SDSVLPASHGHLPQAGSLER 20 0 Q8N4C8;Q8N4C8-4;Q8N4C8-3;Q8N4C8-2;Q8N4C8-5 Q8N4C8;Q8N4C8-3 MINK1 Misshapen-like kinase 1 1 SDSVLPASHGHLPQAGS(1)LER;SDSVLPAS(0.001)HGHLPQAGS(0.999)LER;SDSVLPAS(0.005)HGHLPQAGS(0.995)LER;SDSVLPASHGHLPQAGS(1)LER;SDSVLPAS(0.011)HGHLPQAGS(0.989)LER;SDSVLPASHGHLPQAGS(1)LER 139.47 7.0595e-05 70504000.0 83758.9 96034.5 237539.0 255901.0 357562.0 299778.0 233367.0 207365.5 234027.0 162304.3 True False 97937.62745631719 105568.17049010028 243202.83063167374 241563.69661223562 287500.2928802939 284057.113950992 211260.788329232 201922.37534690875 237449.20213941418 191728.78478986796 0.510813374025478 0.5506120043779629 1.2684732284629072 1.2599239956430435 1.4995155432471456 1.4815569517238352 1.1018730889092674 1.0531667196879844 1.2384640230190533 1.0 17.548707423629132 -5.255673217744329 8.056693363846946 1.2540738259361284 0.5284252169235852 0.7678463745607264 0.1553360841584452 0.0597607976574492 37.9384217784153 0.04356731682480272 0.10480039803202616 5.5504319476658604e-06 5.255673217744329 -0.7256486090125431 SDSVLPASHGHLPQAGS(ph)LER ddPTM_PC-9_Lapatinib_30min_R1 4 SDSVLPASHGHLPQAGSLER 20 0 Q8N4C8;Q8N4C8-4;Q8N4C8-3;Q8N4C8-2;Q8N4C8-5 Q8N4C8;Q8N4C8-3 MINK1 Misshapen-like kinase 1 1 SDSVLPASHGHLPQAGS(1)LER;SDSVLPASHGHLPQAGS(1)LER;SDSVLPASHGHLPQAGS(1)LER;SDSVLPASHGHLPQAGS(1)LER 103.03 0.00017294 44812800.0 115067.0 84678.0 175061.0 101419.0 152433.0 161755.0 116533.0 108289.0 189971.0 95896.0 True False 113426.12347929651 84481.93329360102 160668.16033500235 108877.691583866 143467.1906348088 154837.11571932165 122566.50853965184 113320.50226843027 168574.46549668457 112471.49582661188 1.008487729674693 0.7511408350417951 1.4285233707809073 0.9680469774467466 1.2755871128092797 1.376678727186321 1.0897561879020674 1.0075486365285586 1.498819449832534 1.0 16.779199893300223 -5.250516845494399 24.982167521286552 1.2018749685865668 0.87981427914887 0.32382059403194996 0.18825820428205733 805.1366281911453 1841510.927958237 0.04554029359832316 0.11799465952388925 5.61672491676993e-06 5.250516845494399 -0.32206068943769683 SDT(ph)SSPEVR ddPTM_PC-9_AZD4547_30min_R2 1 SDTSSPEVR 9 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.001)DT(0.445)S(0.277)S(0.277)PEVR 102.07 0.0080596 68345000.0 51721.0 57015.0 63884.0 77131.0 70389.0 64385.0 62948.0 86498.0 73106.0 67790.0 True False 68167.20213636894 75443.98376090689 63036.856418935946 59349.6396120709 60616.70235258162 60358.995771827496 68550.2500535657 73131.72162630144 76970.23391114296 65416.69273367014 1.0420459868537975 1.153283368635903 0.9636203510864851 0.9072552758620811 0.9266243801008003 0.9226849180157431 1.047901494082759 1.117936700408279 1.176614571826652 1.0 15.997371202599856 -7.540412026172151 4.545586926701848 1.1080689180796848 0.9858524156891889 0.29027249960275747 0.07871054315551892 0.26128833407740587 13.588275526758075 0.04157177345949933 0.02426876194610351 2.8812966469291782e-08 7.540412026172151 -0.12221650239049586 SDT(ph)SSPEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDTSSPEVR 9 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.002)DT(0.416)S(0.291)S(0.291)PEVR 86.898 0.027647 49913000.0 48308.0 40790.0 43209.0 48942.0 50124.0 41655.0 49346.0 36717.0 39223.0 37434.0 True False 56485.5902735086 44839.36162828131 44239.26643104502 46199.93841210486 40302.56201814469 39470.53847056342 44671.589645897984 35753.21765487724 39796.56217237426 44220.48787261905 1.2773624396958314 1.0139951815422068 1.0004246574230493 1.0447631999264184 0.9114002119162437 0.8925848711633786 1.0102011939483428 0.8085215558423391 0.8999575555794795 1.0 15.432427321653506 -1.5228787452965078 0.6379528032874978 0.9187625113077721 28.32815904606738 0.7036413184497006 0.06517036604064304 113.43447051549344 0.7660752312521141 0.027837987952946747 4378.61964306753 0.029999999998883 1.5228787452965078 27.40939653475961 SDTPEVHPPLPISQS(ph)PENESNDRR ddPTM_PC-9_Lapatinib_30min_R1 1 SDTPEVHPPLPISQSPENESNDRR 24 1 Q03164-2;Q03164;Q03164-3;E9PR05;A0A3B3ITZ1 Q03164-2 KMT2A Histone-lysine N-methyltransferase 2A;MLL cleavage product N320;MLL cleavage product C180 1 SDTPEVHPPLPIS(0.161)QS(0.821)PENES(0.018)NDRR 83.77600000000001 1.0571e-05 2668500.0 6695.6 7634.2 6486.2 4779.9 6969.8 6001.8 7901.0 6214.2 6429.7 5947.6 True False 6600.119516177338 7616.523478943848 5952.929673456054 5131.429791278971 6559.850067154024 5745.117004879139 8310.075120110094 6502.934418052437 5705.5194782573835 6975.634735321156 0.9461675914247064 1.0918753300509771 0.8533889601921628 0.7356219162818194 0.9403947190551988 0.8235977402584908 1.1913002092887681 0.9322355118631429 0.8179211920841356 1.0 12.76810878301413 SDTS(ph)SPEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SDTSSPEVR 9 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SDT(0.012)S(0.494)S(0.494)PEVR 125.57 0.0014222999999999998 62615000.0 66453.0 72153.0 77719.0 77266.0 95357.0 69290.0 79582.0 57238.0 66015.0 57452.0 True False 77702.18039342288 79315.87299743504 79572.11571094871 72937.03651975191 76672.480375952 65656.31042192625 72043.41683621476 55735.56314867398 66980.34448688992 67867.59281021827 1.1449084485831933 1.1686855200423891 1.1724611470081223 1.0746960883629628 1.1297362585167166 0.9674176982455301 1.0615289839095012 0.8212397234204295 0.9869267748185883 1.0 16.05043522275587 -6.766717058665345 1.0430053537069839 0.9394118312474986 1.1581593410043385 0.6425728147132348 0.06291507950566678 0.2945577167601638 0.6847165428851956 0.033430767346530554 0.030160147165532038 1.7111297470667815e-07 6.766717058665345 0.21874750975683988 SDTS(ph)SPEVR ddPTM_PC-9_Lapatinib_30min_R1 1 SDTSSPEVR 9 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.003)DT(0.071)S(0.463)S(0.463)PEVR 68.557 0.042736 49503000.0 38821.0 41948.0 45376.0 44309.0 47022.0 43494.0 41049.0 46264.0 55047.0 38323.0 True False 38267.40542110053 41850.87198327743 41645.36043642531 47567.63167049096 44256.25840880894 41633.863009466055 43174.31636570045 48413.59433503556 48847.02718939206 44947.07948781234 0.8513880291482999 0.931114378513192 0.9265420781725694 1.0583030580082338 0.9846303455780543 0.9262862789729267 0.9605588807479118 1.0771243623996345 1.0867675440989935 1.0 15.45593975679454 -2.634150945222849 0.3825478409280769 1.0286445268591238 1.5423215101423226e-10 0.5153698482590453 0.05041049566061617 27.212632197706384 0.8281861361072893 0.04318791244168732 18.049154495858367 0.0023219296364323182 2.634150945222849 -1.0286445267048916 SDTSGDYEITLLK ddPTM_PC-9_Lapatinib_30min_R1 1 SDTSGDYEITLLK 13 0 P12429;D6RA82 P12429 ANXA3 Annexin A3;Annexin 0 158.31 0.0011264 1805600.0 22910.0 22978.0 22076.0 20108.0 22596.0 19130.0 20125.0 17973.0 24125.0 20396.0 False True 22583.29919882054 22924.795852764117 20260.99649582434 21586.80939832161 21266.947705445258 18311.85449420807 21166.974027618737 18808.09119366233 21407.78845248756 23921.421424038304 0.9440617594791795 0.9583375271223351 0.8469812949937977 0.9024049622999963 0.8890336125291617 0.7655002672962712 0.8848543592960717 0.7862447159917655 0.8949212537585735 1.0 14.546015497366552 -5.2582884194457025 24.637189596364585 0.8620664032717947 0.9511996536626081 0.1993297817288704 0.06195340706818861 290.1420737196314 2268569.111986755 0.015110205624698987 0.036647616996161536 5.517109206758516e-06 5.2582884194457025 0.08913325039081332 SDTSGHFER ddPTM_PC-9_AZD4547_30min_R2 5 SDTSGHFER 9 0 P20073-2;P20073 P20073-2 ANXA7 Annexin A7 0 ;;;; 156.83 7.9546e-05 14117520.0 27525.8 22920.8 86065.0 170991.0 127532.0 104862.0 65071.3 130088.0 76796.1 109207.0 False True 36278.43182779262 30329.500359326405 84923.72186612789 131571.66673461546 109826.38316256029 98304.96256310295 70862.51964018868 109985.88872485256 80855.38506365451 105383.69617002402 0.3442508959759933 0.28780068892623933 0.805852564984185 1.248501158303845 1.0421572515863224 0.9328289492190482 0.6724239347788719 1.0436708212189052 0.7672475724632394 1.0 16.685292160443694 -5.340742821551303 4.090249356326863 0.9544955656924603 0.3118992028827268 0.7378607327594515 0.1503345761222106 0.10825451726529575 3.37397046863298 0.041844604485496296 0.09604423547230849 4.563070497069463e-06 5.340742821551303 -0.6425963628097335 down SDTSGHFER ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SDTSGHFER 9 0 P20073-2;P20073 P20073-2 ANXA7 Annexin A7 0 ;;;; 121.5 0.0013536 4091960.0 25152.600000000002 25628.15 69837.09999999999 70403.09999999999 92076.6 75537.6 62937.7 64001.50000000001 66163.8 41571.299999999996 False True 29410.438393505236 28172.343361457162 71502.28132267653 66458.64255692979 74034.85120740357 71576.27527965508 56975.78542651143 62321.528440194605 67131.32040538795 49107.84761177024 0.5988948777803103 0.573683122587209 1.4560255600683008 1.3533202082552869 1.5075971521435363 1.4575323244771896 1.1602175252505955 1.2690747298250005 1.3670181787665607 1.0 15.583665970401238 -5.256523083797334 24.97936293688913 1.337860683702809 0.5862888998991412 0.8049581422951524 0.14454762837913696 153.92294429468677 782065.2469901238 0.036807299882319844 0.0911137826367273 5.539580989493791e-06 5.256523083797334 -0.7515717838036678 SDTSGHFER ddPTM_PC-9_Lapatinib_30min_R1 4 SDTSGHFER 9 0 P20073-2;P20073 P20073-2 ANXA7 Annexin A7 0 ;;; 120.45 0.0014068 10578690.0 40250.3 30366.600000000002 69866.9 42666.9 65907.1 71788.0 51067.5 55803.4 78489.0 38300.8 False True 39676.323340999 30296.28800341836 64122.71317603327 45804.76615860595 62030.57395634402 68717.79458600142 53711.525274803425 58396.22968432735 69648.7422941885 44921.042247391946 0.8832458321534726 0.674434218079108 1.42745381602886 1.0196728274100832 1.3808801143732463 1.5297462202135588 1.195687423702237 1.299974950775274 1.550470309896521 1.0 15.45510378074522 -5.260483905202968 24.9995838318703 1.3084863814164358 0.7788399922321395 0.5611586714689223 0.18441274918582984 55.47276858269375 1451368.903497179 0.046129869357221444 0.1086094136384393 5.489288983372994e-06 5.260483905202968 -0.5296463891842963 SDTSGHFQR ddPTM_PC-9_AZD4547_30min_R2 2 SDTSGHFQR 9 0 P50995;P50995-2 P50995 ANXA11 Annexin A11 0 ; 128.27 0.0011209000000000002 6839400.0 8749.1 6028.3 29991.0 56898.0 42683.0 35513.0 17286.0 45423.0 24631.0 30980.0 False True 11531.131807414888 7976.830085168379 29593.299744228727 43781.04516533699 36757.202212209886 33292.3664959992 18824.420512580808 38403.919066700866 25932.944374816885 29895.399629578107 0.385715927878286 0.2668246681431283 0.989894770128763 1.4644743240702698 1.2295270398674585 1.1136284146896027 0.6296761624138377 1.2846096570893317 0.8674560198606336 1.0 14.867635875938696 -5.304845868334491 5.213376025628009 1.0923849727843002 0.3230496951727652 0.6502871495145816 0.21912630618664458 0.10933355502992076 7.409259413293118 0.059613878675082305 0.13305783015219025 4.956260579152691e-06 5.304845868334491 -0.769335277611535 SDTSGHFQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SDTSGHFQR 9 0 P50995;P50995-2 P50995 ANXA11 Annexin A11 0 ; 120.99 0.0013796 3394200.0 5653.1 9347.8 20147.2 18716.0 27983.0 21379.9 18614.7 17571.1 22061.2 14226.8 False True 6610.058176185548 10275.787806542 20627.585656681476 17667.403198090688 22499.932027646275 20258.7004068371 16851.38085724268 17109.877243119365 22383.803314310047 16806.006220713174 0.3933152284591411 0.6114354399010773 1.2273936702021602 1.051255305160833 1.3388030286407615 1.2054440621275342 1.0026999059701396 1.018081096627923 1.331893075626874 1.0 14.036689302806753 -5.1392353054011135 3.5641613073256546 1.1484821895662751 0.42965874701404516 0.8134553900392657 0.1250009687524342 0.09416295391912298 2.123383252064555 0.03277478297264618 0.1071724744009705 7.257126520097839e-06 5.1392353054011135 -0.71882344255223 down SDTSGHFQR ddPTM_PC-9_Lapatinib_30min_R1 2 SDTSGHFQR 9 0 P50995;P50995-2 P50995 ANXA11 Annexin A11 0 ; 125.57 0.0011937999999999999 5168600.0 7973.9 8813.5 19779.0 9914.0 18576.3 19448.8 13806.0 16393.9 25126.0 10244.8 False True 7860.190723765832 8793.09288224983 18152.846969147915 10643.108632134503 17483.678556410992 18617.02016136715 14520.807126723184 17155.620442874355 22296.04529149026 12015.60002966208 0.654165476910177 0.7318063900714845 1.5107732384845731 0.8857742106811642 1.4550816033531613 1.5494041175978395 1.2084962124968102 1.4277789207799412 1.8555915007531505 1.0 13.552621074476075 -4.698971973555107 0.7255780248340613 1.4257839360104119 2.5319783112712e-14 0.46008676759945066 0.2762633387621749 2.7931256173344305 1.0284258668295596 0.11142031364606263 3.3595798659092777 1.999990931431525e-05 4.698971973555107 -1.4257839360103866 SDVEAIFSK ddPTM_PC-9_Lapatinib_30min_R1 1 SDVEAIFSK 9 0 B4DY08;B2R5W2;G3V4W0;G3V576;G3V555;G3V575;G3V5X6;G3V3K6;G3V251;B4DSU6;B7ZW38;P0DMR1;A0A0G2JPF8;G3V4M8;G3V2H6;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;A0A0G2JNQ3;B2RXH8;O60812 B4DY08;P07910-2;A0A0G2JNQ3 HNRNPC;HNRNPCL3;HNRNPCL4;HNRNPCL2;HNRNPCL1 Heterogeneous nuclear ribonucleoprotein C-like 3;Heterogeneous nuclear ribonucleoprotein C-like 4;Heterogeneous nuclear ribonucleoproteins C1/C2;Heterogeneous nuclear ribonucleoprotein C-like 2;Heterogeneous nuclear ribonucleoprotein C-like 1 0 139.96 0.0036933 5746100.0 49298.0 43017.0 54599.0 43507.0 45823.0 40104.0 40444.0 36435.0 47131.0 44171.0 False True 48595.001479854014 42917.396779456605 50110.08097823485 46706.64991509743 43127.78123148425 38388.84540699006 42537.99242598816 38127.903112506916 41822.61046856754 51805.89849584213 0.9380206287466317 0.8284268399070638 0.9672659375313531 0.9015701159752308 0.8324878533849892 0.7410130220996186 0.8211032654785864 0.7359760996243895 0.8072943754063867 1.0 15.660828748624077 -6.337319206974327 3.864155774778984 0.8033306149267189 0.907718435053952 0.21567348476505277 0.07640700607076535 0.2944320449976589 8.462182527224394 0.022961612522759044 0.026691089507012485 4.599184087289676e-07 6.337319206974327 0.10438782012723313 SDVLELTDDNFESR ddPTM_PC-9_AZD4547_30min_R2 3 SDVLELTDDNFESR 14 0 H7BZJ3 H7BZJ3 PDIA3 0 ;; 188.15 6.256e-08 25543000.0 52566.5 54033.2 58927.4 97170.0 74819.0 62301.0 53233.4 79373.0 59751.4 64782.6 False True 69281.55354887647 71498.37522318414 58145.984173520854 74768.95776153465 64431.67331994774 58405.30862127244 57971.069473239586 67107.72666008947 62909.73701909922 62514.58089228881 1.1082463092609867 1.1437071832309682 0.9301187553941224 1.1960242985610006 1.0306663245645369 0.9342669788013687 0.927320772942914 1.0734731914097695 1.0063210233703919 1.0 15.93190510256601 -6.517052221657679 24.742737110510568 0.9883262772756668 1.0896753899682132 0.3150229921120813 0.07374746552143333 297.32913666769326 1262635.5003007816 0.02392092492122171 0.024684495993009953 3.040519397015517e-07 6.517052221657679 0.10134911269254643 SDVLELTDDNFESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SDVLELTDDNFESR 14 0 H7BZJ3 H7BZJ3 PDIA3 0 ;; 109.72 0.0025943000000000003 18723940.0 27129.5 31830.9 32844.5 36443.1 38081.7 30184.7 39235.7 28764.9 27251.7 25536.3 False True 31721.988517950467 34990.861388910496 33627.637443459884 34401.31125712434 30619.8642567708 28601.761194872546 35519.01045413123 28009.851853930817 27650.20455734877 30165.829044760416 1.0515868292855801 1.1599502648175404 1.1147592659748484 1.1404066238683268 1.0150513089276174 0.9481510073014374 1.1774584547776792 0.9285291583523021 0.9166068174795087 1.0 14.880627611916482 -6.860336309329973 0.6554655878873453 0.9625040695300192 1.1256196485770311 0.3477695247371887 0.0753815597845184 0.8812573954895024 0.8184888799864798 0.061591043723820134 0.05937569055205721 1.379315735240702e-07 6.860336309329973 0.1631155790470119 SDVLELTDDNFESR ddPTM_PC-9_Lapatinib_30min_R1 2 SDVLELTDDNFESR 14 0 H7BZJ3 H7BZJ3 PDIA3 0 ; 147.87 6.9576e-08 16636000.0 41014.4 31026.2 40050.0 37144.7 36217.4 37071.0 37871.1 31058.0 42627.0 31974.0 False True 40429.527134880205 30954.360740144064 36757.243597470755 39876.44514908678 34087.16373814802 35485.55974672177 39831.88025328453 32501.06806280334 37825.898377790145 37500.663297323066 1.078101654211706 0.8254350195014737 0.9801758253191917 1.0633530621292586 0.9089749551331612 0.9462648557806937 1.0621646859277787 0.8666798185706593 1.0086727820755719 1.0 15.194628493219184 SDYDMVDYLNELR ddPTM_PC-9_Lapatinib_30min_R1 2 SDYDMVDYLNELR 13 0 Q14974;Q14974-2;J3KTM9 Q14974 KPNB1 Importin subunit beta-1 0 ; 114.76 0.0015862 1540000.0 8668.4 9630.2 12182.0 9228.3 10574.400000000001 10375.0 8979.2 12905.0 12508.5 8983.7 False True 8544.78702641013 9607.901863577723 11180.442983879877 9906.979966706349 9952.434582070291 9931.285435306258 9444.099040436975 13504.613412018716 11099.661009655581 10536.520574972203 0.8109685702799163 0.9118666636877962 1.0611133821953718 0.9402515656106414 0.9445655718369389 0.9425583488060012 0.896320466821837 1.2816957282935257 1.0534465273119693 1.0 13.363110910854228 -7.736568277057957 24.999750153507204 1.1256784834241662 0.9355110883420967 0.4657492095687781 0.08881996335537198 177.73545737373826 178655.0206247034 0.0408466134737433 0.02357015706311682 1.834136792952861e-08 7.736568277057957 -0.19016739508206948 SEAAGSPDQGSTYS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 2 SEAAGSPDQGSTYSPAR 17 0 Q96S66-4;Q96S66-3;Q96S66-2;Q96S66 Q96S66-4 CLCC1 Chloride channel CLIC-like protein 1 1 SEAAGS(0.001)PDQGS(0.004)T(0.065)Y(0.001)S(0.929)PAR;SEAAGSPDQGSTYS(1)PAR 269.59 1.1593999999999999e-69 7983000.0 30932.0 28888.0 57011.0 49562.0 52070.0 27641.0 39330.0 50202.0 33484.0 36075.0 True False 40767.73257443134 38225.481064370426 56254.99688967432 38136.24662526686 44840.97929362433 25912.603900428425 42830.29380769428 42444.4344271958 35253.89588105916 34812.025230375424 1.1710818978396935 1.0980539285320456 1.615964498399499 1.0954906062744914 1.2880887853228973 0.744357839825367 1.2303304253129885 1.2192463422139739 1.0126930463757728 1.0 15.087298126527688 SEAAGSPDQGSTYS(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SEAAGSPDQGSTYSPAR 17 0 Q96S66-4;Q96S66-3;Q96S66-2;Q96S66 Q96S66-4 CLCC1 Chloride channel CLIC-like protein 1 1 SEAAGSPDQGSTYS(1)PAR;SEAAGSPDQGS(0.016)T(0.065)YS(0.92)PAR;SEAAGSPDQGSTYS(1)PAR 217.65 1.81e-22 6838000.0 49238.0 45460.0 53723.0 38882.0 68307.0 45433.0 44198.0 38865.0 38008.0 38092.0 True False 57573.020905171325 49972.96836532651 55003.960065612075 36703.56759714481 54922.733695902316 43050.41349977455 40011.2454741904 37844.83493087138 38563.795095928435 44997.77806389392 1.2794636398139787 1.1105652437853295 1.222370579887523 0.8156751105583063 1.2205654603192984 0.9567230950525103 0.8891826929182377 0.841037859183495 0.8570155406600377 1.0 15.457566144206343 -5.242089954775921 0.45634150663694656 0.8831939160198697 1.4075285871244294 0.47360266623643155 0.12109123497597958 2.9334641405238453 0.646160886515727 0.09082946038553641 0.7962463724754448 5.726774008744507e-06 5.242089954775921 0.5243346711045597 SEAAGSPDQGSTYS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 2 SEAAGSPDQGSTYSPAR 17 0 Q96S66-4;Q96S66-3;Q96S66-2;Q96S66 Q96S66-4 CLCC1 Chloride channel CLIC-like protein 1 1 SEAAGSPDQGS(0.107)T(0.346)YS(0.547)PAR;SEAAGSPDQGSTYS(1)PAR 247.91 1.9121999999999996e-47 6692100.0 61880.0 66399.0 33067.0 19024.8 27076.0 29800.0 27348.0 21774.3 41218.0 9518.2 True False 60997.579852597766 66245.25719504243 30348.35890231126 20423.94725687234 25483.442913464136 28525.52346719289 28763.945625208285 22786.013468990237 36575.59479521792 11163.408187795712 5.46406427378359 5.9341426991323685 2.718556769740742 1.8295440705286241 2.2827654856626727 2.5552701278430487 2.5766275980711866 2.041134130874192 3.2763824613350456 1.0 13.446489928668049 -5.303660952069218 4.896482297977147 2.3030351511006484 5.720692826850143 0.8514376825193779 0.5717864813081822 0.05933011528988641 3.454117476989412 0.14084625086128336 0.31953867927934215 4.969801558454722e-06 5.303660952069218 3.4176576757494943 SEAAPASLEGGSLKS(ph)PPPFFYR ddPTM_PC-9_AZD4547_30min_R2 2 SEAAPASLEGGSLKSPPPFFYR 22 1 Q8WYL5-4;Q8WYL5 Q8WYL5-4 SSH1 Protein phosphatase Slingshot homolog 1 1 SEAAPAS(0.002)LEGGS(0.165)LKS(0.831)PPPFFY(0.001)R;SEAAPASLEGGS(0.021)LKS(0.978)PPPFFYR 69.528 0.00095312 28222000.0 26621.0 22509.0 41150.0 47941.0 38901.0 33654.0 32323.0 41637.0 26880.0 28970.0 True False 35085.924248801784 29784.59406251433 40604.32411306762 36888.94313106647 33500.26763013791 31549.610059875482 35199.684382051935 35202.95837307582 28300.821923392396 27955.769117781718 1.2550512955297237 1.0654185165511816 1.4524488287907837 1.3195467087901604 1.1983311025712229 1.128554536523477 1.259120585584698 1.2592376988363525 1.0123428121099771 1.0 14.77085841641953 -8.265277125918228 23.37139026000512 1.0061712809553567 1.2412182759542296 0.4786116706441953 0.09854156122035762 124.7284624859337 759539.226591568 0.0861319007417666 0.02564917767358746 5.42903790768572e-09 8.265277125918228 0.23504699499887294 SEAAPASLEGGSLKS(ph)PPPFFYR ddPTM_PC-9_Lapatinib_30min_R1 1 SEAAPASLEGGSLKSPPPFFYR 22 1 Q8WYL5-4;Q8WYL5 Q8WYL5-4 SSH1 Protein phosphatase Slingshot homolog 1 1 SEAAPAS(0.01)LEGGS(0.286)LKS(0.701)PPPFFY(0.003)R 54.833999999999996 0.006509100000000001 9747700.0 7467.8 8213.1 10183.0 8063.0 9170.8 10936.0 13818.0 12103.0 12600.0 10778.0 True False 7361.3078025732075 8194.083071561365 9345.793047516723 8655.979917379509 8631.391574486519 10468.292773061134 14533.428428006731 12665.349564173759 11180.85531611786 12640.962939217734 0.5823375828225275 0.6482166834094399 0.7393260380917684 0.6847563717258371 0.6828112396175302 0.8281246312797866 1.1497089658350117 1.0019291746264336 0.8844939558702456 1.0 13.62581874612774 -6.979538818970501 3.604819868235579 1.0093975916939883 0.6726983205372544 0.8358514952421683 0.07110907110638567 0.09317638577592531 2.6011747332818755 0.028354204995291416 0.02356083700269623 1.0482410934295511e-07 6.979538818970501 -0.3366992711567339 SEAEDLAEPLSSTEGVAPLSQAPS(ph)PLAIPAIK ddPTM_PC-9_AZD4547_30min_R2 1 SEAEDLAEPLSSTEGVAPLSQAPSPLAIPAIK 32 0 Q6P4R8-3;Q6P4R8;Q6P4R8-2;E9PQ59 Q6P4R8-3 NFRKB Nuclear factor related to kappa-B-binding protein 1 SEAEDLAEPLSSTEGVAPLS(0.035)QAPS(0.965)PLAIPAIK 74.766 4.4206000000000003e-07 1117600.0 10331.0 13560.0 15730.0 10690.0 13168.0 16563.0 15768.0 20888.0 16677.0 14186.0 True False 13616.043101850835 17943.004819747395 15521.409922200583 8225.58565885361 11339.850496225192 15527.312991671635 17171.321453336473 17660.239558489036 17558.512173229716 13689.35245788234 0.9946447900836031 1.3107270687165191 1.1338308345814665 0.6008747078549586 0.8283701169295044 1.1342620507028436 1.2543560045054734 1.2900712150427727 1.2826400830317952 1.0 13.740766584516573 -6.972651302340677 7.902095260117323 1.2260015375859814 0.9801903042465347 0.25341712195285826 0.18952968554641722 0.30577981351694583 72.03793424675622 0.07477939881502675 0.065305966718894 1.0649977681689238e-07 6.972651302340677 -0.24581123333944666 SEAEDLAEPLSSTEGVAPLSQAPS(ph)PLAIPAIK ddPTM_PC-9_Lapatinib_30min_R1 2 SEAEDLAEPLSSTEGVAPLSQAPSPLAIPAIK 32 0 Q6P4R8-3;Q6P4R8;Q6P4R8-2;E9PQ59 Q6P4R8-3 NFRKB Nuclear factor related to kappa-B-binding protein 1 SEAEDLAEPLSSTEGVAPLS(0.005)QAPS(0.995)PLAIPAIK;SEAEDLAEPLSSTEGVAPLS(0.016)QAPS(0.984)PLAIPAIK 104.83 9.711199999999999e-16 3384800.0 26191.0 45308.0 42409.0 35144.0 51005.0 52409.0 50890.0 50797.0 55741.0 46036.0 True False 25817.511537158825 45203.09210971521 38922.295723474075 37728.60699694723 48004.986179688196 50167.58924134608 53524.835193317645 53157.214063565596 49462.861601248085 53993.261260885825 0.4781617360065214 0.8371987735895766 0.7208732129627894 0.6987651072723561 0.8890921766650962 0.929145379808514 0.9913243605474241 0.984515712187108 0.9160932391590932 1.0 15.720491739563329 -4.09511268201674 0.3224918927287473 1.0130524460808323 1.28614012106685e-18 0.7531434856022751 0.07862119450023906 5.852384726378724 0.34933308365409554 0.0817685580928884 2.5203606609321403 8.033176663967309e-05 4.09511268201674 -1.0130524460808323 down SEAEEGEVRT(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 1 SEAEEGEVRTPTK 13 1 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 SEAEEGEVRT(0.997)PT(0.003)K 71.545 0.01849 108730000.0 160590.0 206940.0 213190.0 194780.0 197390.0 219060.0 178080.0 271800.0 227560.0 179340.0 True False 211654.27952049446 273829.3080677379 210362.96130412864 149876.48032100167 169985.8056994147 205362.14357034268 193928.775013328 229799.55534265243 239588.3570270523 173061.3611868477 1.223001356680533 1.5822671576707115 1.215539736088218 0.8660308649669396 0.9822285259613066 1.1866435243660256 1.1205781214441655 1.3278501553824409 1.3844127619473532 1.0 17.40092412954838 -5.50983029343178 24.736451942111422 1.127003957918425 1.4017016114399885 0.30271076682854814 0.16731145821330318 657.604318986489 1246643.6412470494 0.047267848207110545 0.09156098675434093 3.091503244112864e-06 5.50983029343178 0.2746976535215635 SEAEEGEVRT(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 2 SEAEEGEVRTPTK 13 1 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 SEAEEGEVRT(0.986)PT(0.014)K;SEAEEGEVRT(0.942)PT(0.057)K 77.279 0.011748 183667000.0 335140.0 389150.0 391480.0 327210.0 422080.0 493880.0 457720.0 435660.0 497710.0 420850.0 True False 330360.8421428516 388248.94708430493 359294.02555649995 351274.1149405623 397254.08424120746 472757.90369051107 481418.5019588396 455902.3540550227 441652.65868135105 493593.36175262416 0.6692975792255886 0.7865765165595662 0.7279150276266652 0.711667016131006 0.8048205568054227 0.9577882125721228 0.9753342310955019 0.9236395571371335 0.8947702560527863 1.0 18.91296346651132 -6.613998257303172 3.2622393677297903 0.9476062636408356 0.7300633317164871 0.8869434668894137 0.03830462942269758 0.07980994167362308 1.6959794113134201 0.013382453417487722 0.013472511991299755 2.432213768817243e-07 6.613998257303172 -0.21754293192434848 SEAGAGPGPK ddPTM_PC-9_Lapatinib_30min_R1 1 SEAGAGPGPK 10 0 Q9GZP8;Q9GZP8-2;K7EQZ3 Q9GZP8 IMUP Immortalization up-regulated protein 0 88.37 0.046221 1430400.0 11883.0 9082.8 11865.0 9064.1 8858.1 6516.9 9173.7 15049.0 12577.0 10123.0 False True 11713.546240924681 9061.769334645567 10889.505500224492 9730.70415095121 8337.083973694658 6238.18737863589 9648.66929874117 15748.231479075512 11160.445818318602 11872.747061950378 0.9865910711147968 0.7632411679759106 0.9171849988384773 0.8195832102021309 0.7022034521743695 0.5254207258089368 0.8126737012416525 1.3264185109733564 0.9400053551284226 1.0 13.535366157336941 -7.635032026053561 8.69028499375494 1.0987067721614916 0.7786766395180802 0.45940487603695057 0.14872886410392977 0.222273849169272 16.098205188698202 0.07142598253379308 0.041091009338068175 2.317223765299528e-08 7.635032026053561 -0.3200301326434114 SEALSS(ph)VLDQEEAMEIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEALSSVLDQEEAMEIK 17 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 S(0.002)EALS(0.195)S(0.803)VLDQEEAMEIK 80.488 0.040072 0.0 6193.8 7318.0 6942.7 5920.4 6510.6 5716.4 6197.1 4868.3 5247.0 5471.1 True False 7242.288006873752 8044.482677022866 7108.240298336369 5588.699182195775 5234.894666733158 5416.621920852926 5610.065824881334 4740.512283390226 5323.727448651244 6462.967120796228 1.120582523709561 1.2447042552851169 1.099841630860818 0.8647265377867581 0.8099831809276212 0.838101419922682 0.8680325491413272 0.733488534722145 0.8237280724391753 1.0 12.657980936840389 -5.7093718412187595 3.2070990283851004 0.8326614010161598 1.181928731829866 0.8077895254017808 0.06916764487822175 0.08856751068465357 1.8458348318059916 0.01869839201489484 0.0336945355244229 1.9526668741893714e-06 5.7093718412187595 0.3492673308137061 SEANDAVNS(ph)STKEEK ddPTM_PC-9_AZD4547_30min_R2 1 SEANDAVNSSTKEEK 15 1 O15234;J3KSY7;K7EQ38 O15234 CASC3 Protein CASC3 1 SEANDAVNS(0.932)S(0.063)T(0.005)KEEK 81.643 0.0040628999999999995 11888000.0 24518.0 24869.0 21683.0 19922.0 17976.0 25869.0 24001.0 22030.0 27713.0 22100.0 True False 32314.21399391916 32907.41791019897 21395.469252579485 15329.290691831764 15480.342688346303 24251.40734055146 26137.042503902117 18625.76969903837 29177.852602789186 21326.285726716484 1.5152293469198699 1.5430449695689032 1.0032440494678514 0.7187979608013978 0.7258808630212301 1.1371603874823142 1.2255787453489364 0.8733714786398531 1.3681638226499357 1.0 14.380345101427922 -5.263116508205936 22.197688600885037 0.9941921340585407 1.5291373043219139 0.5363140097165886 0.19410501195026794 22.42706090813293 296868.5214350929 0.05312992980625486 0.12104133869209964 5.456114702351326e-06 5.263116508205936 0.5349451702633732 SEANDAVNS(ph)STKEEK ddPTM_PC-9_Lapatinib_30min_R1 1 SEANDAVNSSTKEEK 15 1 O15234;J3KSY7;K7EQ38 O15234 CASC3 Protein CASC3 1 S(0.001)EANDAVNS(0.96)S(0.028)T(0.01)KEEK 68.08800000000001 0.01345 10174000.0 21473.0 26431.0 19957.0 21893.0 29585.0 20421.0 26087.0 26497.0 24834.0 24049.0 True False 21166.79108233407 26369.800643415794 18316.212496247805 23503.08425290705 27844.868466347943 19547.641433676057 27437.65721532867 27728.147352054213 22036.93340638659 28205.837606721776 0.7504400818534736 0.9349057812462044 0.6493766556992032 0.8332702109617902 0.9872023250857898 0.6930353108541485 0.972765198392476 0.9830641351152882 0.7812898065163267 1.0 14.7837061597158 -7.583323907617551 0.13809105498097052 1.081703149998772 0.6793634610794618 0.19598148914470692 0.11355660948599826 10.586642661156278 1.268442199839889 1.4444346773362697 1.7946683886595747 2.6102138658774414e-08 7.583323907617551 -0.40233968891931016 SEAPAEVTHFS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 SEAPAEVTHFSPK 13 0 Q6PID6 Q6PID6 TTC33 Tetratricopeptide repeat protein 33 1 SEAPAEVT(0.002)HFS(0.998)PK;SEAPAEVTHFS(1)PK 154.81 5.6726000000000005e-05 108797000.0 278040.0 268070.0 299580.0 355680.0 330610.0 316320.0 289590.0 310320.0 308130.0 284850.0 True False 366450.9364087318 354718.3851054343 295607.37345790525 273683.47120122117 284710.508244002 296540.4603951923 315362.94898983435 262367.17444419325 324417.12274013733 274877.48820159194 1.33314277137159 1.290459933355066 1.0754149981213095 0.9956561848400801 1.0357723730187707 1.0788095537955185 1.1472854727141235 0.9544876743481308 1.1802244151118464 1.0 18.068429232907143 -5.244815407669176 3.9361592364573283 1.0561821080176164 1.3223989762054282 0.7119681125298778 0.06478354007910442 0.10512000179944883 3.7734985228341626 0.016249193245874188 0.044193452158994694 5.690947672285226e-06 5.244815407669176 0.2662168681878119 SEAPAEVTHFS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SEAPAEVTHFSPK 13 0 Q6PID6 Q6PID6 TTC33 Tetratricopeptide repeat protein 33 1 SEAPAEVT(0.349)HFS(0.651)PK;SEAPAEVT(0.005)HFS(0.995)PK;SEAPAEVT(0.002)HFS(0.998)PK;SEAPAEVT(0.022)HFS(0.978)PK;SEAPAEVT(0.002)HFS(0.998)PK;SEAPAEVT(0.025)HFS(0.975)PK 145.79 5.664e-05 107813500.0 616296.0 596650.0 518687.0 728946.0 635152.0 598537.0 657203.0 595633.0 593889.0 506722.0 True False 720622.7403991531 655881.4688775206 531054.4652114006 688105.5188948174 510698.5250767823 567148.6660558303 594947.9741023205 579998.2648753298 602573.5030973959 598586.687390854 1.2038736503483485 1.0957167653300237 0.8871805477769381 1.1495503214315743 0.8531738774593158 0.9474795848333061 0.9939211590147551 0.9689461478060125 1.0066603815128596 1.0 19.19120066799256 -5.006240219019149 4.142113550051104 0.9761950640206853 1.1902252557129562 0.4874754044294428 0.07510125552854051 0.15583562183154698 6.347356547094453 0.018361841239561152 0.0712661298758691 9.857341009013022e-06 5.006240219019149 0.2140301916922709 SEAPAEVTHFS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 SEAPAEVTHFSPK 13 0 Q6PID6 Q6PID6 TTC33 Tetratricopeptide repeat protein 33 1 SEAPAEVT(0.017)HFS(0.983)PK;SEAPAEVTHFS(1)PK 149.19 6.814e-05 108290000.0 868650.0 754820.0 815800.0 737650.0 768020.0 738210.0 720980.0 706410.0 738750.0 656210.0 True False 856262.8917090982 753072.2606660012 748728.073079069 791899.2417282652 722846.573585417 706638.4791515593 758308.8166177672 739232.387476493 655544.1956176247 769635.0241551357 1.1125570755424727 0.978479717048589 0.9728352395357562 1.0289282801254658 0.9392069629093601 0.9181475075504384 0.985283664098055 0.960497332210138 0.8517598277667341 1.0 19.55381492846314 -1.5228787452813117 0.6906911117855554 0.9473421096677194 18.663213855305713 0.5050890771302857 0.045856613747940055 233.9340552005849 1.289120737382323 0.01824020538614193 6389.526876472726 0.029999999999932705 1.5228787452813117 17.715871745637994 SECDS(ph)SPEPK ddPTM_PC-9_AZD4547_30min_R2 3 SECDSSPEPK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SECDS(0.5)S(0.5)PEPK;SECDS(0.5)S(0.5)PEPK;SECDS(0.5)S(0.5)PEPK 135.8 0.00011411 51214000.0 313847.0 300588.0 319989.0 385236.0 396963.0 351042.0 344882.0 366305.0 351657.0 358968.0 True False 413643.8175768647 397747.1926812853 315745.73678290175 296425.79203686863 341851.5395301512 329091.2882462357 375575.82987503713 309700.97910150967 370244.871098006 346400.6395813557 1.1941196704393389 1.1482288057030865 0.9115044855705172 0.8557310760023873 0.9868675183258832 0.9500308332108183 1.0842238349471331 0.8940542935365259 1.06883425950214 1.0 18.402082068242784 -5.174218347659631 5.283474517509035 0.965416818463902 1.1801772551196372 0.5815329996240444 0.06881066454343414 0.14853034969296874 6.7560602838791874 0.017617764701863065 0.049146260167798564 6.695479001561921e-06 5.174218347659631 0.2147604366557352 SECDS(ph)SPEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SECDSSPEPK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SECDS(0.623)S(0.377)PEPK;SECDS(0.5)S(0.5)PEPK;SECDS(0.5)S(0.5)PEPK;SECDS(0.5)S(0.5)PEPK 126.03 0.00035989 59417000.0 478420.0 530829.0 449384.0 555137.0 588186.0 464217.0 556025.0 527084.0 454052.0 404778.0 True False 559407.0567742807 583526.194993356 460099.018858311 524034.4736684369 472935.17562853073 439872.643312677 503354.28672760434 513248.60349165986 460691.65151801 478161.04717911617 1.1699134843259833 1.2203549378098353 0.9622260566238905 1.095937188442991 0.9890708965495723 0.9199257152118111 1.0526877705683353 1.0733802063541995 0.9634654563265539 1.0 18.867137081837946 -5.257024063826396 24.99977640732539 1.0107529147067693 1.1951342280502728 0.6714241973513253 0.0525694995820254 214.3268387919561 1213520.546730129 0.013640728076765257 0.03353001643571493 5.5331944948456205e-06 5.257024063826396 0.1843813133435035 SECDS(ph)SPEPK ddPTM_PC-9_Lapatinib_30min_R1 3 SECDSSPEPK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SECDS(0.5)S(0.5)PEPK;SECDS(0.5)S(0.5)PEPK;SECDS(0.5)S(0.5)PEPK 139.32 0.00011605 81555000.0 167619.0 207194.0 207614.0 214181.0 221387.0 196187.0 185713.0 198751.0 197025.0 171781.0 True False 165228.72232244036 206714.25502296156 190544.778333216 229932.5852268715 208365.45192358852 187796.53934423407 195328.31043931204 207985.6970361976 174833.96973477147 201473.11696620556 0.8201030728588732 1.0260140813607164 0.945757832123962 1.1412569016115417 1.0342097003370383 0.9321171090817761 0.9695006131864023 1.0323248092254633 0.867778155058263 1.0 17.62022782382556 -4.755646180888364 24.878000168922977 0.9969388968300819 0.8201027690898581 0.35942049278199684 0.0696996625172351 200.2409045361617 859811.1058127302 0.017409194122673697 0.15101241177924882 1.755309968065355e-05 4.755646180888364 -0.17683612774022373 SECDSS(ph)PEPK ddPTM_PC-9_Lapatinib_30min_R1 1 SECDSSPEPK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SECDS(0.308)S(0.692)PEPK 139.31 0.00012086 20611000.0 143590.0 172580.0 162160.0 181360.0 181230.0 183580.0 156510.0 159320.0 168830.0 147400.0 True False 141542.38026881873 172180.40161328335 148827.83075570155 194697.81939922503 170570.4077118891 175728.7113458816 164613.32199068862 166722.58882625485 149814.58754128395 172877.8936018455 0.8187419300399651 0.9959654067155136 0.8608841052776037 1.1262158240291436 0.9866525103824392 1.0164903544614083 0.9521941675770819 0.9643950730348039 0.8665919304079527 1.0 17.399393873607785 -4.116101060353886 1.7659907095221268 0.9776189182932966 5.0021022480334354e-14 0.2829844086702169 0.07234378266279218 11.808987728058142 6.545189776314681 0.019414298942066237 34.62627114030787 7.654184732582218e-05 4.116101060353886 -0.9776189182932465 SECNMCNT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 SECNMCNTPK 10 0 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 SECNMCNT(1)PK 88.021 0.021095 0.0 9214.9 9968.5 10264.0 10891.0 11132.0 10631.0 9321.9 11420.0 10256.0 11058.0 True False 12145.046518172996 13190.622680357817 10127.892653621531 8380.248214272653 9586.513952307014 9966.241889419873 10151.531041086842 9655.301405493332 10798.111221961026 10670.862785793252 1.1381503784625937 1.2361345980307488 0.9491165669476503 0.7853393284589669 0.8983822718693473 0.9339677671320559 0.9513317943327108 0.9048285597250865 1.0119248498197528 1.0 13.381389208613635 -5.309846157609353 6.274029875121129 0.9196510910492862 1.1869670660541614 0.7241295971710255 0.06349178815213362 0.09367706820593703 9.223134053664419 0.016849572546718847 0.03625101415501904 4.899523469971971e-06 5.309846157609353 0.26731597500487514 SECQDMSLS(ph)SPTSVLGGSR ddPTM_PC-9_Lapatinib_30min_R1 1 SECQDMSLSSPTSVLGGSR 19 0 O95613-2;O95613 O95613-2 PCNT Pericentrin 1 SECQDMS(0.018)LS(0.774)S(0.204)PT(0.003)SVLGGSR 141.22 0.00018955 3459300.0 15137.0 14733.0 16316.0 15143.0 25645.0 26796.0 17517.0 17690.0 24542.0 18733.0 True False 14921.143604214169 14698.886643692831 14974.561461581356 16256.666735567147 24136.611520009898 25649.99754452687 18423.94454866073 18511.941980520034 21777.821521282905 21970.974089846517 0.6791298166024283 0.6690138809314627 0.6815611087767645 0.7399156118016573 1.098568111787278 1.1674492646359518 0.838558384954585 0.8425635524769468 0.9912087389583298 1.0 14.423311213053832 -6.124637684264558 5.202655132874153 0.9822615814409407 0.6811768167159356 0.7060870218821192 0.09441662028614024 0.14580169018290154 5.576796221794376 0.031710520126047796 0.041507822571979394 7.505200792174606e-07 6.124637684264558 -0.3010847647250051 SECQDMSLSS(ph)PTSVLGGSR ddPTM_PC-9_AZD4547_30min_R2 2 SECQDMSLSSPTSVLGGSR 19 0 O95613-2;O95613 O95613-2 PCNT Pericentrin 1 SECQDMS(0.016)LS(0.23)S(0.686)PT(0.052)S(0.016)VLGGSR;SECQDMS(0.005)LS(0.259)S(0.676)PT(0.044)S(0.015)VLGGSR 109.42 0.0001452 18465900.0 151084.0 171230.0 208741.0 261270.0 221610.0 207945.0 189432.0 242700.0 198675.0 223210.0 True False 199125.56925757715 226576.74891484866 205972.95795105337 201038.23808126125 190843.2767670458 194942.16627743543 206291.08102159004 205196.29169117566 209176.55489694895 215395.48583983642 0.9244649138359509 1.0519103872182651 0.9562547569089287 0.9333447137826699 0.8860133536361708 0.9050429516540117 0.9577316823388944 0.9526489883996703 0.9711278492274823 1.0 17.716628489292354 -10.853371555812606 24.059906070722015 1.000000000000059 0.9487813419101615 0.11635652962703824 0.04238906803262322 0.0 0.0 0.04430058265596446 0.010744469503938075 1.401614056148972e-11 10.853371555812606 -0.05121865808989756 SECQDMSLSS(ph)PTSVLGGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SECQDMSLSSPTSVLGGSR 19 0 O95613-2;O95613 O95613-2 PCNT Pericentrin 1 SECQDMS(0.098)LS(0.304)S(0.592)PT(0.006)S(0.001)VLGGSR;SECQDMS(0.003)LS(0.086)S(0.84)PT(0.053)S(0.018)VLGGSR 93.115 0.00073781 15405200.0 142978.0 140931.0 167321.0 185870.0 217240.0 204570.0 213230.0 205885.0 202055.0 166681.0 True False 167181.35145577745 154921.69829946858 171310.56720842596 175456.30649867086 174673.3814703884 193841.9890750971 193031.31074848716 200480.73690318904 205009.67212449532 196898.9458539296 0.8490718461225369 0.7868081651102286 0.8700430896949215 0.8910982521401306 0.8871219737253986 0.9844744888522649 0.9803572584471242 1.0181910118092588 1.0411923295749015 1.0 17.58709586188055 -6.5510355883254014 0.7676891957546778 1.0264918424445826 0.8178144746028927 0.9020707389088668 0.025139866274807698 0.18313288336944042 0.24013040019668677 0.015722098966653827 0.01933896188347738 2.8116704182111954e-07 6.5510355883254014 -0.2086773678416899 SECQDMSLSS(ph)PTSVLGGSR ddPTM_PC-9_Lapatinib_30min_R1 4 SECQDMSLSSPTSVLGGSR 19 0 O95613-2;O95613 O95613-2 PCNT Pericentrin 1 SECQDMS(0.128)LS(0.201)S(0.515)PT(0.113)S(0.042)VLGGS(0.001)R;SECQDMS(0.073)LS(0.212)S(0.626)PT(0.064)S(0.025)VLGGSR;SECQDMSLS(0.214)S(0.786)PTSVLGGSR;SECQDMS(0.001)LS(0.01)S(0.989)PTSVLGGSR 240.82 1.3845999999999998e-118 11397000.0 67615.0 71116.0 85997.0 71712.0 89141.0 98741.0 86465.0 82633.0 100556.0 86162.0 True False 66650.79770092745 70951.33527135402 78926.65861801973 76985.93970421911 83897.90163794902 94518.07760651316 90941.73462350584 86472.43084659748 89230.3243783768 101054.98689635153 0.6595498129081822 0.7021062240513302 0.781026855200842 0.7618222719001569 0.8302203009931621 0.9353133428581507 0.8999232736211376 0.8556968191514303 0.8829878377986149 1.0 16.62478099252371 -3.088554242757717 0.22254387252472577 0.9772616151220049 8.32097507065878e-15 0.8753386275736297 0.03544791363485576 9.341566557371598 0.21868524396245506 0.06298816101540454 2.85228506579591 0.0008155409208804662 3.088554242757717 -0.9772616151219966 SECS(ph)SDFGGK ddPTM_PC-9_AZD4547_30min_R2 1 SECSSDFGGK 10 0 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 SECS(0.5)S(0.5)DFGGK 101.97 0.010386 0.0 10079.0 9615.6 7896.6 8536.7 9827.0 11256.0 16415.0 15960.0 13514.0 13703.0 True False 13283.912343776465 12723.65465669344 7791.885924453219 6568.695705700245 8462.690676367325 10552.160540618012 17875.903199931392 13493.748724314677 14228.3224506222 13223.262140868592 1.0045866294006547 0.9622175315854145 0.5892559522336895 0.49675304291205474 0.639985094919357 0.7979997997623357 1.3518527432563765 1.020455359696009 1.0760069867062008 1.0 13.690790509034528 -7.098768286792676 6.854913781984335 1.1123361425698943 0.7282519598561303 0.5226449732945626 0.17082073574175038 0.22237081706840325 13.2932216214373 0.07186013438226713 0.05566796006593415 7.96584246120376e-08 7.098768286792676 -0.384084182713764 SECS(ph)SDFGGK ddPTM_PC-9_Lapatinib_30min_R1 1 SECSSDFGGK 10 0 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 SECS(0.873)S(0.127)DFGGK 94.82 0.0061551999999999996 5614400.0 11115.0 22617.0 21959.0 22150.0 23094.0 24676.0 25030.0 24124.0 26972.0 17988.0 True False 10956.498061758633 22564.631726084328 20153.615784191286 23778.98489023393 21735.656324550935 23620.665002565514 26325.930927269394 25244.889108991825 23934.129332248474 21097.20183249662 0.5193341822649689 1.0695556645491908 0.9552743507979385 1.12711558049402 1.0302625199836164 1.1196112731017216 1.2478399332900543 1.1965989285890228 1.134469372871148 1.0 14.364764043407009 -4.544072634512489 1.8853432895914972 1.1155158369910303 1.8355828440734493e-28 0.8000022037153108 0.08618675024476613 0.8146794606787748 1.751698317784583 0.02434233497413495 1.9797788447582776 2.8571126594764803e-05 4.544072634512489 -1.1155158369910303 SEDADRCTLPEHES(ph)PSQDISDACEAESTER ddPTM_PC-9_AZD4547_30min_R2 5 SEDADRCTLPEHESPSQDISDACEAESTER 30 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 SEDADRCTLPEHES(0.988)PS(0.011)QDIS(0.001)DACEAESTER;SEDADRCT(0.008)LPEHES(0.889)PS(0.102)QDISDACEAESTER;SEDADRCT(0.004)LPEHES(0.809)PS(0.186)QDIS(0.002)DACEAESTER;S(0.027)EDADRCT(0.025)LPEHES(0.679)PS(0.269)QDISDACEAESTER;S(0.001)EDADRCT(0.007)LPEHES(0.794)PS(0.199)QDISDACEAESTER 100.79 6.1263e-13 153930200.0 47197.4 18636.7 88329.8 227659.0 133039.0 70461.2 42600.1 69993.5 41934.5 83493.4 True False 62205.19143309403 24660.648814468026 87158.48913833401 175175.73484648773 114568.83127029958 66055.25002528359 46391.42637267119 59177.61286562151 44151.0720590215 80570.32147941289 0.7720608567881727 0.30607608808870457 1.0817691618694176 2.1741967964127853 1.421973118222867 0.8198459285304186 0.5757880261719571 0.7344840107252447 0.5479818281512363 1.0 16.297960891510478 -6.939979850371236 7.164533117521504 0.6929771700125612 1.1560367543421695 0.17178345480235646 0.45975684051362975 0.44136675453021046 43.31603953847784 0.18602476964148565 0.16366275619696233 1.1482068927377002e-07 6.939979850371236 0.46305958432960825 SEDADRCTLPEHES(ph)PSQDISDACEAESTER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SEDADRCTLPEHESPSQDISDACEAESTER 30 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 S(0.001)EDADRCT(0.028)LPEHES(0.64)PS(0.283)QDIS(0.034)DACEAES(0.007)T(0.007)ER;SEDADRCT(0.001)LPEHES(0.861)PS(0.137)QDISDACEAESTER 103.86 2.8363000000000004e-15 72852000.0 34410.0 3459.6 28750.0 77742.0 57543.0 92610.0 45001.0 83292.0 57372.0 49404.0 True False 40234.93337152087 3803.0462243001225 29435.509034982177 73386.3677829647 46267.86222588177 87753.36856941263 40738.179500973834 81105.67325516893 58210.95696283958 58360.55411815115 0.6894200025939627 0.06516466955746927 0.5043733645055851 1.2574652330132736 0.7927934017249445 1.5036417987354203 0.6980430552201277 1.3897344615846212 0.9974366734933888 1.0 15.832705960881222 -5.666212513651407 5.237227824928013 1.0948284948250677 0.35878059662036593 0.5596060710104529 0.2736628611455381 0.13211903204396613 5.764934535166781 0.06894931253174026 0.12100682778566839 2.1566888167165506e-06 5.666212513651407 -0.7360478982047018 SEDADRCTLPEHES(ph)PSQDISDACEAESTER ddPTM_PC-9_Lapatinib_30min_R1 3 SEDADRCTLPEHESPSQDISDACEAESTER 30 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 S(0.001)EDADRCT(0.052)LPEHES(0.869)PS(0.078)QDISDACEAESTER;SEDADRCTLPEHES(0.892)PS(0.108)QDIS(0.001)DACEAESTER;SEDADRCT(0.003)LPEHES(0.888)PS(0.11)QDISDACEAESTER 117.24 7.9252e-09 68917000.0 56742.1 25894.7 54343.3 38669.0 26238.5 36156.5 16780.5 17044.3 47398.9 22221.7 True False 55932.94724877326 25834.742413115626 49875.40364520433 41512.84725600253 24695.20301687578 34610.170779918124 17649.31218238292 17836.240401276285 42060.336749455484 26062.691236445964 2.146092540533836 0.9912538263503818 1.9136705105671805 1.5928073919684522 0.9475308130244856 1.327958439361757 0.6771868654033009 0.684359118537005 1.6138140289456553 1.0 14.66969844400066 -6.243811656116722 9.50782414305498 1.0220501898313996 1.6316716178744426 0.3885838847361881 0.3792825233883478 0.3720879467293744 190.86425641227208 0.10931855272891158 0.1379491764097603 5.704115935032355e-07 6.243811656116722 0.609621428043043 SEDADRCTLPEHESPS(ph)QDISDACEAESTER ddPTM_PC-9_Lapatinib_30min_R1 1 SEDADRCTLPEHESPSQDISDACEAESTER 30 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 SEDADRCTLPEHES(0.102)PS(0.888)QDIS(0.008)DACEAES(0.001)TER 69.149 4.3903e-05 19906000.0 16262.0 6521.1 14149.0 10456.0 7817.7 12059.0 2365.9 4775.5 11377.0 5501.7 True False 16030.10089791443 6506.000793605191 12985.723836719455 11224.969120193491 7357.878256189558 11543.264680901992 2488.3947255623916 4997.387163819866 10095.602454878803 6452.661514445557 2.484261860323509 1.008266244717815 2.0124601000142883 1.739587470234442 1.1402857936554542 1.7889152646640636 0.3856385028087447 0.7744691322537574 1.564564084490997 1.0 12.65567863305779 -6.73307148052382 1.3269860315984874 0.9578346525659335 1.7604624316879323 0.33188766561506977 0.4934493513416152 0.513662214879511 1.896637453582205 0.22742204426925358 0.21057493763896176 1.848964272924031e-07 6.73307148052382 0.8026277791219988 SEDARS(ph)SPSQR ddPTM_PC-9_Lapatinib_30min_R1 1 SEDARSSPSQR 11 1 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;E5RFR3;E5RG53 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 SEDARS(0.706)S(0.293)PSQR 120.53 0.0041386 8681000.0 25803.0 7526.3 10858.0 10122.0 6116.5 5453.3 4115.7 5169.9 12723.0 5402.4 True False 25435.044488309333 7508.873314764494 9965.297153092071 10866.405646002162 5756.739495501677 5220.0750712631925 4328.790807725235 5410.112427647853 11290.00176087044 6336.197641754493 4.014244177090784 1.1850756146371229 1.5727566778255802 1.7149726476955751 0.9085479685112279 0.8238497860078989 0.6831843090245829 0.8538421200746814 1.7818260097303782 1.0 12.629401622025943 -3.2790846526657127 1.4697691612810637 1.1083470765651169 199.99999999999503 0.8189564419023942 0.3962316461262514 40.952216179824774 1.6609765164910775 0.11758149398060376 26269.431784372067 0.0005259147451149922 3.2790846526657127 198.89165292342992 SEDARSS(ph)PSQR ddPTM_PC-9_AZD4547_30min_R2 1 SEDARSSPSQR 11 1 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;E5RFR3;E5RG53 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 SEDARS(0.041)S(0.958)PSQR 106.54 0.011684 11357000.0 14840.0 4291.3 10242.0 41219.0 25175.0 8352.1 5549.2 9438.1 9352.0 21788.0 True False 19558.811308824555 5678.378804054719 10106.18438799608 31716.596377201753 21679.885802131615 7829.84186667516 6043.068049775163 7979.658510962053 9846.327627513596 21025.208751751074 0.9302552730752607 0.270074788369547 0.48066987145392276 1.5085032805945506 1.0311377193972457 0.3724025744107324 0.2874201212994791 0.37952814667285867 0.46831057630728873 1.0 14.35983250410221 -6.7733492716799635 24.991555092236503 0.44937072894317753 0.8289539397342203 0.17797209666484592 0.35876968252266117 391.53337487880657 821583.4113281341 0.13483048465726452 0.11982807070645932 1.6851971978909255e-07 6.7733492716799635 0.37958321079104274 SEDARSS(ph)PSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEDARSSPSQR 11 1 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;E5RFR3;E5RG53 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 SEDARS(0.074)S(0.907)PS(0.019)QR 106.29 0.011834 9786800.0 3208.9 0.0 1071.9 3501.3 6625.4 13123.0 3196.8 11121.0 10410.0 5702.5 True False 3752.1033913360457 0.0 1097.4581612033871 3305.133512367758 5327.200430831853 12434.806778278817 2893.975961172266 10829.085533673493 10562.226556214879 6736.318109034838 0.5569961706980072 0.0 0.1629166175705779 0.4906439183646731 0.7908178243077538 1.8459352092652945 0.429607971941056 1.6075674216081604 1.5679524608626605 1.0 12.717744553038298 -6.353153130803729 2.4748629088409206 1.2765681659200427 0.2416771247309116 0.5770983674901835 0.3952106569206401 0.20660325739260066 2.476822849441316 0.1306627686796199 0.1557957724497257 4.4345225655731093e-07 6.353153130803729 -1.0348910411891312 SEDARSS(ph)PSQR ddPTM_PC-9_Lapatinib_30min_R1 1 SEDARSSPSQR 11 1 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;E5RFR3;E5RG53 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 SEDARS(0.408)S(0.591)PS(0.001)QR 106.54 0.011684 7558200.0 31351.0 9577.9 14236.0 12825.0 7478.3 6508.5 6330.4 5015.8 17042.0 6512.1 True False 30903.928990930734 9555.722961014426 13065.571032549158 13768.193282945827 7038.441096903492 6230.14662705453 6658.157137114912 5248.852379078144 15122.550499784173 7637.707808172182 4.046230854480214 1.2511244474147085 1.7106665194195148 1.8026603830293375 0.921538408339281 0.8157089513673733 0.8717480825845194 0.6872287485863213 1.9799854720291041 1.0 12.898924013242013 -3.1815688420131942 1.3674271424840987 1.1533130722926628 199.9999999998637 0.7727761960635027 0.45269580148467065 47.627466138538885 1.6618826184482869 0.13317253292042167 28429.32109071004 0.0006583110697607721 3.1815688420131942 198.84668692757103 SEDDESGAGELTR ddPTM_PC-9_Lapatinib_30min_R1 1 SEDDESGAGELTR 13 0 P33993;P33993-2;P33993-3 P33993 MCM7 DNA replication licensing factor MCM7 0 123.01 0.0016224 0.0 5625.8 6974.1 7686.3 9234.9 7743.2 8835.2 5536.9 5327.7 6071.2 6209.8 False True 5545.575060354635 6957.951899937426 7054.362083976022 9914.065352723306 7287.760199716927 8457.339091857137 5823.573589740228 5575.244391725072 5387.397523429742 7283.155655961612 0.7614247617810167 0.9553485094393127 0.9685859285736519 1.3612321116064805 1.0006322182269365 1.1612190500053914 0.7995948274115704 0.7654984535668227 0.7397064923389217 1.0 12.830347963489212 -7.280359131150509 24.024315627690584 0.8066580921686818 1.0414148377732488 0.28847412404400385 0.15906379110370067 625.190915873979 793863.5248578539 0.06883714896745839 0.046511280870307904 5.2437366058474475e-08 7.280359131150509 0.23475674560456705 SEDDSAKFDS(ph)NEEDSASVFSPSFGLK ddPTM_PC-9_AZD4547_30min_R2 2 SEDDSAKFDSNEEDSASVFSPSFGLK 26 1 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 SEDDS(0.01)AKFDS(0.986)NEEDS(0.004)ASVFSPSFGLK;SEDDS(0.007)AKFDS(0.722)NEEDS(0.206)AS(0.061)VFS(0.004)PSFGLK 90.912 2.1361000000000002e-07 31967000.0 98721.0 95259.0 84688.0 121395.0 109020.0 114148.0 97978.0 107146.0 101161.0 113807.0 True False 130112.2244756378 126049.60885872554 83564.98178584373 93409.25828405358 93884.4548221805 107010.30751514416 106697.8521914638 90589.04767013906 106508.16393572543 109822.65157015502 1.1847485251484913 1.1477560144157026 0.7609084336527987 0.8505463758938973 0.854873320575463 0.9743919490669525 0.9715468591040611 0.8248666953034777 0.9698196356849726 1.0 16.74481612383957 -5.17092152790993 7.032925314178278 0.896605634433487 1.1721893802021957 0.669671965003326 0.07457586417798748 0.14625637083843288 9.749448990694717 0.019224590680846417 0.051833377376035064 6.746499182784161e-06 5.17092152790993 0.2755837457687087 SEDDSAKFDS(ph)NEEDSASVFSPSFGLK ddPTM_PC-9_Lapatinib_30min_R1 1 SEDDSAKFDSNEEDSASVFSPSFGLK 26 1 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 SEDDS(0.002)AKFDS(0.995)NEEDS(0.002)AS(0.001)VFSPSFGLK 113.42 2.077e-11 25176000.0 94270.0 77221.0 71408.0 66588.0 73532.0 68446.0 68302.0 76707.0 69873.0 63604.0 True False 92925.69251299919 77042.19951894427 65537.1098828514 71485.10365105626 69206.99232947433 65518.724135419005 71838.34335574735 80271.08725267115 62003.16694469067 74597.86665299737 1.245688337781244 1.0327667931486173 0.8785386610009455 0.9582727611176795 0.9277342025262001 0.8782921962123756 0.9630080132172366 1.0760507083408104 0.8311654170099428 1.0 16.18684675248104 -4.825246830387333 2.9745459552775357 0.9409872111455092 1.2807654931928107 0.6665286178618408 0.06565816447607124 0.1989231295513761 2.7040331490549216 0.016381797650239994 0.15532707468795548 1.4953855152069037e-05 4.825246830387333 0.33977828204730154 SEDES(ph)ETEDEEEKSQEDQEQK ddPTM_PC-9_Lapatinib_30min_R1 1 SEDESETEDEEEKSQEDQEQK 21 1 P25205;J3KQ69;A0A499FHX9;P25205-2;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 1 S(0.001)EDES(0.895)ET(0.104)EDEEEKSQEDQEQK 130.19 1.1387000000000001e-05 17661000.0 42758.0 43725.0 32682.0 34698.0 39138.0 38710.0 36245.0 40122.0 31169.0 43055.0 True False 42148.26307914313 43623.75744895597 29995.012116168295 37249.80666913486 36835.979788268574 37054.46353741735 38121.588751852956 41986.21459256217 27658.41899587916 50496.999382818634 0.8346686653521016 0.8638881118112287 0.5939959301101355 0.7376637646673503 0.7294686860305177 0.7337953539874086 0.7549278020036899 0.8314595937525703 0.5477240100188965 1.0 15.623910042579384 -10.245004817088633 5.831242201515016 1.0000000092246832 0.7390580881034051 0.4063026040995571 0.09554431413419705 1.1175309547921809e-08 2.540881448166386e-09 0.09039255773289555 0.0219234148350123 5.688466213006528e-11 10.245004817088633 -0.2609419211212781 SEDES(ph)ETEDEEEKSQEDQEQKR ddPTM_PC-9_Lapatinib_30min_R1 1 SEDESETEDEEEKSQEDQEQKR 22 2 P25205;J3KQ69;A0A499FHX9;P25205-2;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 1 S(0.022)EDES(0.755)ET(0.223)EDEEEKSQEDQEQKR 54.071999999999996 0.0048283 23294000.0 24604.0 19955.0 18417.0 18993.0 18219.0 15694.0 21061.0 24649.0 21265.0 24011.0 True False 24253.142448178995 19908.795423531556 16902.82535167589 20389.80857879065 17147.394239932164 15022.804204500859 22151.435527735553 25794.28252559854 18869.911769622726 28161.269357353583 0.8612233397727123 0.7069566066393556 0.6002153218729878 0.7240372697712357 0.6088999051264203 0.5334562165457944 0.7865922251814719 0.9159488586356295 0.6700660943287821 1.0 14.781424743861523 -8.76065048753354 0.6530900848446592 0.9949788997034701 0.6796471483809237 0.3755217347516182 0.11204781063698999 1.178793442967601 1.0456587962468447 0.12375785628767275 0.047119098123849484 1.735199893962164e-09 8.76065048753354 -0.3153317513225464 SEDESET(ph)EDEEEKSQEDQEQK ddPTM_PC-9_AZD4547_30min_R2 1 SEDESETEDEEEKSQEDQEQK 21 1 P25205;J3KQ69;A0A499FHX9;P25205-2;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 1 S(0.001)EDES(0.435)ET(0.557)EDEEEKS(0.008)QEDQEQK 65.753 0.0030343 18754000.0 12180.0 16719.0 14792.0 16429.0 21069.0 15872.0 13627.0 12248.0 17232.0 12752.0 True False 16052.986640261655 22123.08979213546 14595.848415078895 12641.547875519736 18143.933027412546 14879.521330906979 14839.776601003055 10355.353031040486 18142.848340174758 12305.55636140672 1.3045315602801844 1.7978130482193362 1.1861185294193686 1.0273040490202272 1.4744504429166994 1.2091709544781617 1.2059411346523332 0.8415184756308495 1.474362296781252 1.0 13.587022266252237 -1.522878745305935 0.21946175642611804 1.0505454161657717 3.608908908138332 0.1991526825337937 0.23513658619004885 74.47828619921755 0.95087419940633 0.36341890190178205 67.42674405286552 0.0299999999982318 1.522878745305935 2.5583634919725604 SEDFGVNEDLADSDAR ddPTM_PC-9_AZD4547_30min_R2 3 SEDFGVNEDLADSDAR 16 0 P04083 P04083 ANXA1 Annexin A1 0 ;; 308.74 4.032299999999998e-273 58253000.0 57543.0 62336.0 80728.0 106036.0 91513.0 71031.0 73934.0 88337.0 77152.0 79212.0 False True 75840.47703124609 82484.89295308065 79657.49397326175 81591.03843986924 78807.9995793631 66589.42034120817 80513.98277086364 74686.54643231745 81230.09721107021 76438.81199025646 0.9921723671073454 1.0790970032814595 1.0421079540510856 1.0674032774118667 1.0309945631992374 0.8711467199371992 1.0533128482050014 0.9770762324490029 1.0626813145843303 1.0 16.222017735715625 -6.538432114238902 24.99991235630887 0.990287883808629 1.0476215705184824 0.1812251772750344 0.05306927334988914 377.9319479879238 607469.2289868791 0.016993307904001883 0.016997963681317507 2.8944622230310486e-07 6.538432114238902 0.05733368670985339 SEDFGVNEDLADSDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SEDFGVNEDLADSDAR 16 0 P04083 P04083 ANXA1 Annexin A1 0 ;;; 305.69 7.071199999999998e-128 58026300.0 113187.0 172291.0 153492.0 148891.0 193154.0 137230.0 146173.0 102898.0 109767.0 94771.0 False True 132347.32355484812 189394.91184844883 157151.83140165132 140549.11998113515 155306.860267591 130033.41722039165 132326.43523912452 100197.03652944298 111372.1347162382 111952.2320931769 1.1821767291311935 1.691747527559942 1.403740045762153 1.2554383003650815 1.3872600605080423 1.1615080359645347 1.1819901467349962 0.8949981135351534 0.9948183491647054 1.0 16.772523767233437 -7.07903124539268 0.898250416566526 0.9481538719673372 1.4295415706584376 0.6334167429049613 0.13489058731391135 0.35499141202366286 0.583283068970693 0.09431602593334956 0.06406301812686159 8.336212074381313e-08 7.07903124539268 0.4813876986911003 SEDFGVNEDLADSDAR ddPTM_PC-9_Lapatinib_30min_R1 4 SEDFGVNEDLADSDAR 16 0 P04083 P04083 ANXA1 Annexin A1 0 ;;; 361.58 1.896699999999999e-239 115372600.0 103870.0 106286.0 114016.0 93611.0 110092.0 106645.0 113539.0 98853.0 110716.0 98304.0 False True 102388.79475257474 106039.90129719223 104642.04459448755 100495.46521714168 103616.60500919985 102084.04195163719 119417.49386940624 103446.07126061866 98245.99818883384 115295.71541815394 0.8880537700922498 0.9197210920857487 0.9075969927847908 0.8716322618985902 0.8987029971877416 0.8854105426329095 1.0357496237939412 0.8972238984375174 0.852121848869368 1.0 16.814979375459153 SEDLLDYGPFR ddPTM_PC-9_Lapatinib_30min_R1 1 SEDLLDYGPFR 11 0 B7Z4L4;P04843 B7Z4L4 RPN1 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 0 100.02 0.019913999999999998 1220300.0 14726.0 12246.0 13189.0 7326.6 10022.0 10680.0 10093.0 9489.1 9672.5 6156.1 False True 14516.004539582344 12217.645139391992 12104.65133101229 7865.42260482112 9432.5256640101 10223.24129629598 10615.566154571721 9929.998227662672 8583.081194059521 7220.173682512366 2.0104785809711 1.6921539116134783 1.6765041761156496 1.0893675070270927 1.3064125710516028 1.4159273371854197 1.4702646530904333 1.3753129307281957 1.1887638125448683 1.0 12.817817826467815 -5.597871196286108 4.833575751349641 1.2969443692645874 1.8163638136507616 0.7052379937152229 0.15782951496891023 0.1175665390563825 5.053803341240278 0.04399106560962082 0.07900713468001822 2.5242293012168e-06 5.597871196286108 0.5194194443861742 SEDMPFS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 SEDMPFSPK 9 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 S(0.001)EDMPFS(0.999)PK;SEDMPFS(1)PK;SEDMPFS(1)PK;SEDMPFS(1)PK 152.64 9.258399999999999e-05 242936000.0 1702510.0 1755020.0 1710970.0 2093290.0 1974570.0 1935040.0 1738720.0 1901240.0 1850370.0 1845800.0 True False 2243872.7655921048 2322295.893713353 1688281.4198720632 1610714.3315081075 1700435.0390591898 1814041.642903111 1893462.7116530398 1607447.0441488717 1948176.780594777 1781179.1038177952 1.2597681843350665 1.3037969560364386 0.9478448384294346 0.9042966695801046 0.9546681944642524 1.0184498790800307 1.063038920451388 0.9024623299832427 1.0937568133485496 1.0 20.76440116111361 -5.260029505855371 24.999935740737882 0.9820167432582532 1.2817825977437514 0.7959936657072465 0.0599628719533204 48.75665377413008 864534.5769809766 0.01554138735019055 0.03680050871575115 5.49503539460292e-06 5.260029505855371 0.2997658544854982 SEDMPFS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SEDMPFSPK 9 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SEDMPFS(1)PK;SEDMPFS(1)PK;SEDMPFS(1)PK;SEDMPFS(1)PK 81.676 0.014868000000000001 133146600.0 1050095.0 1055851.0 797925.0 1150926.0 1156703.0 932801.0 1133356.0 1004410.0 905228.0 858613.0 True False 1227855.3431783544 1160668.9094038347 816950.558147415 1086443.3475724391 930055.3506119646 883883.2734576898 1025996.3148931287 978045.3017603649 918465.2469768766 1014272.7401232328 1.210577090959944 1.1443360976681825 0.8054545151712907 1.0711550301947754 0.9169677088028256 0.8714453602985516 1.01155860184951 0.9642823503681403 0.9055406998962471 1.0 19.95201421763641 -5.097148570828774 6.165030690673855 0.9459348504189892 1.1950622867851508 0.6350439842479155 0.07170052720601554 0.12269718542013479 6.320486780440473 0.01736673034715642 0.04796010076080506 7.995606809245188e-06 5.097148570828774 0.24912743636616164 SEDMPFS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 SEDMPFSPK 9 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 S(0.004)EDMPFS(0.996)PK;SEDMPFS(1)PK;SEDMPFS(1)PK;SEDMPFS(1)PK 158.06 0.00011045 188787000.0 1654070.0 1483920.0 1357830.0 1377230.0 1358390.0 1358530.0 1345120.0 1327000.0 1321730.0 1178710.0 True False 1630482.6584807122 1480484.0744117717 1246194.4587753715 1478516.0885046006 1278492.1708974936 1300428.8387881075 1414763.7318772918 1388657.264451675 1172862.8489660686 1382448.4529676521 1.1794166031873479 1.0709144859858393 0.901440090659591 1.0694909349644999 0.9248027788327302 0.9406707613557119 1.0233753951840083 1.0044911703367272 0.8483953571276573 1.0 20.398794257354233 -4.970354046966175 3.4346332773628654 0.9679691266133748 1.1751700936918135 0.5537584427934852 0.0613519931513131 0.17693443595768632 4.169858302838044 0.015220871538948024 0.07530735952007091 1.0706461337326568e-05 4.970354046966175 0.2072009670784387 SEDPPGQEAGS(ph)EEEGSSASGLAK ddPTM_PC-9_AZD4547_30min_R2 2 SEDPPGQEAGSEEEGSSASGLAK 23 0 K7EIG1;I3L2B0;A0A494C0R8;O75153 K7EIG1 CLUH Clustered mitochondria protein homolog 1 SEDPPGQEAGS(1)EEEGSSASGLAK;SEDPPGQEAGS(0.991)EEEGS(0.007)S(0.002)ASGLAK 95.654 5.3336e-06 8499200.0 60809.0 59679.0 80600.0 103707.0 87813.0 77008.0 69326.0 88592.0 61730.0 73176.0 True False 80144.99709422585 78969.06966354759 79531.19133689548 79798.95340717777 75621.68071271418 72192.6775863462 75495.87969774268 74902.14204163449 64992.92177570729 70614.13051304099 1.1349710958973673 1.1183182330477555 1.1262787031302142 1.1300706080695921 1.0709142796674158 1.0223545494625 1.0691327521734497 1.060724553250735 0.9203954124125967 1.0 16.10766928799267 -7.035815902704711 0.5674779394545565 0.9789064706854242 1.1393084857382427 0.7106940582419861 0.035168546148383766 0.4975372650827196 0.3393841310610246 0.031794522414810754 0.02961019342159306 9.208398327491792e-08 7.035815902704711 0.16040201505281848 SEDPPGQEAGS(ph)EEEGSSASGLAK ddPTM_PC-9_Lapatinib_30min_R1 1 SEDPPGQEAGSEEEGSSASGLAK 23 0 K7EIG1;I3L2B0;A0A494C0R8;O75153 K7EIG1 CLUH Clustered mitochondria protein homolog 1 SEDPPGQEAGS(1)EEEGSSASGLAK 99.971 3.3675999999999997e-06 5539700.0 56850.0 50377.0 54581.0 46139.0 46242.0 50942.0 37343.0 39792.0 50529.0 38472.0 True False 56039.308574986804 50260.35515165363 50093.56086875285 49532.21597519201 43522.13647526993 48763.32941160207 39276.4378192977 41640.881587837925 44837.89192604122 45121.83393928228 1.2419554721644406 1.1138810363799918 1.1101845048266594 1.0977438559311334 0.9645471532437053 1.0807036229338534 0.8704530465705278 0.9228543689928813 0.9937072147017972 1.0 15.461538085613697 -5.527281268552131 0.5873342361537586 0.9464440234593968 1.268300572066637 0.7031694213851628 0.05663662802142855 0.9910550200496289 0.4672363571506487 0.03410414503444517 0.1949280147710338 2.969742070847597e-06 5.527281268552131 0.3218565486072401 SEDPPTT(ph)PIR ddPTM_PC-9_AZD4547_30min_R2 3 SEDPPTTPIR 10 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0;H7C151 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SEDPPT(0.026)T(0.974)PIR;S(0.014)EDPPT(0.053)T(0.933)PIR;S(0.003)EDPPT(0.165)T(0.832)PIR 139.31 0.00029551 498147900.0 520523.0 569774.0 696969.0 833180.0 779652.0 772793.0 614005.0 766211.0 643690.0 632226.0 True False 686038.4864490099 753942.3029621493 687726.7356685447 641103.2235026794 671410.777573128 724470.1315445828 668650.2555147029 647810.6957271844 677714.13928082 610091.9601746184 1.1244837356202075 1.2357846885023014 1.1272509401233641 1.050830473686598 1.1005074995267257 1.187476935997038 1.0959827356573002 1.0618246723686873 1.1108393218078911 1.0 19.218667193323085 -14.522878642028477 0.048951698727530905 0.485673137946759 1.3801993510140498 0.4243722088745545 0.04830640971599207 589.9792324419828 2.130173888522353 39.82520243167372 9.147527114867547 3.0000007132386697e-15 14.522878642028477 0.8945262130672909 SEDPPTT(ph)PIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SEDPPTTPIR 10 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0;H7C151 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SEDPPT(0.017)T(0.983)PIR;S(0.135)EDPPT(0.249)T(0.616)PIR;SEDPPT(0.005)T(0.994)PIR 113.67 0.0031138999999999997 402636000.0 358731.0 410143.0 457700.0 457440.0 580720.0 523350.0 615240.0 492700.0 473000.0 445450.0 True False 419457.0730397868 450859.28649934207 468613.30383691634 431811.1198404893 466932.0847333998 495904.60469497956 556960.0132481317 479767.14705880155 479916.7301719141 526206.5588197401 0.797133874538949 0.8568104652868659 0.8905501004928501 0.8206114359521175 0.8873551211157639 0.9424143359354422 1.058443692715215 0.9117468017405556 0.9120310686517246 1.0 19.005269705300442 -6.684048728544141 2.9255034409130802 0.9669897407170591 0.8465368669551945 0.621116250108015 0.0458936119551863 0.18881342438808538 3.272534134828249 0.017060000695311443 0.016574026096530522 2.069909088609667e-07 6.684048728544141 -0.12045287376186464 SEDPPTT(ph)PIR ddPTM_PC-9_Lapatinib_30min_R1 1 SEDPPTTPIR 10 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0;H7C151 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 S(0.001)EDPPT(0.232)T(0.767)PIR 94.363 0.015481 219670000.0 138450.0 152760.0 157080.0 147540.0 163920.0 196170.0 189800.0 217670.0 235180.0 174570.0 True False 136475.67761137956 152406.2936055461 144165.4887463351 158390.58377901194 154278.54787911964 187780.266394605 199626.9153014675 227783.7428434026 208691.55184480958 204744.19190009657 0.6665667843607104 0.7443741978278515 0.7041249249047298 0.7736023293705809 0.753518556240163 0.9171457546704475 0.9750064871138029 1.1125284714037116 1.0192794721456084 1.0 17.643463001097835 -6.946336941208028 1.4086279802567936 1.0494990984118122 0.7171812845963909 0.9260220946761671 0.04022132158803561 0.09574858925223431 0.38979661146913147 0.019541155251812662 0.015044801669463759 1.1315221472104017e-07 6.946336941208028 -0.33231781381542136 SEEAHAEDSVMDHHFR ddPTM_PC-9_AZD4547_30min_R2 4 SEEAHAEDSVMDHHFR 16 0 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 ;;; 84.17299999999999 0.0011172 92034900.0 58985.5 61517.1 148324.0 219467.0 174683.0 175658.0 126467.0 202083.0 149219.0 171735.0 False True 77741.66202538206 81401.29954254298 146357.12684682012 168872.2738813493 150431.28069806355 164674.07749146063 137722.318000958 170855.71575536896 157106.411703374 165722.60992206598 0.469107154792828 0.4911900650178235 0.8831451961542675 1.0190056381610482 0.9077293724061343 0.9936729669470059 0.8310412083524655 1.0309740827501868 0.948008312065904 1.0 17.33841092067258 -5.292888546899039 3.6933739701399864 0.9561656593818125 0.4670802498624026 0.9198603452559693 0.05605822139616746 0.05054864478478614 1.4839013125843898 0.014207007040083399 0.0360218341607155 5.094615975388439e-06 5.292888546899039 -0.48908540951940993 SEEAHAEDSVMDHHFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SEEAHAEDSVMDHHFR 16 0 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 ;;; 79.61399999999999 0.001945 61449200.0 108237.0 139207.0 238349.0 193535.0 245436.0 184595.0 193207.0 162746.0 176424.0 140703.0 False True 126559.38632180498 153026.5509729876 244032.14410361566 182691.86139893593 197344.5776770678 174914.51323907453 174905.03426245277 158474.08994364087 179003.86723858296 166211.3400956646 0.761436531640756 0.9206745513567945 1.4682039382099952 1.099154012558865 1.1873111519556014 1.0523620899657071 1.0523050603032527 0.9534493245312233 1.0769654292875293 1.0 17.342659290610406 -7.226749938905181 2.700377191931532 1.0131532282607556 1.1000761325332216 0.02741077228778399 0.17313420321424522 1.128089819380763 16.303770921368017 0.08309757409913261 0.057430411544932454 5.932668215490977e-08 7.226749938905181 0.08692290427246596 SEEAHAEDSVMDHHFR ddPTM_PC-9_Lapatinib_30min_R1 7 SEEAHAEDSVMDHHFR 16 0 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 ;;;;;; 103.14 0.00039662 48583700.0 91847.0 102006.3 175467.0 111653.09999999999 168299.0 167270.0 120144.0 149474.0 199163.0 110843.09999999999 False True 90537.24493732302 101770.11067959819 161040.7805822073 119864.441437823 158399.98370856472 160116.25202541446 126364.46845089314 156419.10772166454 176731.16566063365 130002.18214585286 0.6964286556032337 0.7828338647840514 1.2387544418410719 0.9220186881428185 1.2184409607128872 1.2316428030859963 0.9720180566593992 1.2032037088898542 1.3594476857500308 1.0 16.9881763141873 -5.177392367537298 5.062413770835503 1.141992748931145 0.7212470147208223 0.6008893610840695 0.1319163555114323 0.14329111189036609 6.243500848458233 0.03345468671944685 0.09394176245041082 6.646723801832781e-06 5.177392367537298 -0.4207457342103227 SEEDNEIES(ph)EEEVQPK ddPTM_PC-9_AZD4547_30min_R2 2 SEEDNEIESEEEVQPK 16 0 P52701-2;P52701;P52701-3;A0A087WWJ1;A0A494C0M1;C9J7Y7 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 SEEDNEIES(1)EEEVQPK;SEEDNEIES(1)EEEVQPK 292.76 1.6015999999999994e-111 42314000.0 95062.0 109616.0 112755.0 73584.0 78024.0 122865.0 112907.0 137279.0 133212.0 94288.0 True False 125289.73858756619 145047.2283422884 111259.79502719187 56620.34566146715 67191.7143922749 115182.23212713514 122955.50427015885 116065.68490759372 140253.31436231203 90987.0058190336 1.377006941373125 1.5941532204145346 1.2228097190985638 0.6222904595199101 0.7384759371674922 1.2659195792883222 1.3513523515072936 1.275629238074278 1.5414653235349391 1.0 16.473372903113372 -6.979112392848489 24.996051489929677 1.3141603195757174 1.105392899111492 0.08210421337021823 0.2911521485509672 651.0828995466741 779143.7183329283 0.11596546917807238 0.10226272965110658 1.0492708484099204e-07 6.979112392848489 -0.20876742046422536 SEEDNEIES(ph)EEEVQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEEDNEIESEEEVQPK 16 0 P52701-2;P52701;P52701-3;A0A087WWJ1;A0A494C0M1;C9J7Y7 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 SEEDNEIES(1)EEEVQPK 255.23 2.3176999999999994e-147 0.0 41039.0 65515.0 46831.0 34468.0 42317.0 29253.0 50313.0 27432.0 31469.0 29327.0 True False 47986.09214280279 72018.89622644892 47947.62864755651 32536.869706763726 34025.287625126235 27718.92118303666 45546.98840542426 26711.939066606534 31929.174591501058 34643.75294759575 1.385129729316263 2.078842218260507 1.3840194715649026 0.9391843243998702 0.9821478543792573 0.8001131177954648 1.314724431683871 0.7710463444019082 0.9216430633193543 1.0 15.080307604810582 -5.577182633914171 3.7560463753434092 0.9622278191330702 1.7380792011008608 0.6887523767034818 0.209685211525183 0.10975759998822653 3.1764278969656647 0.054796214115450166 0.1046117519703822 2.647386598658716e-06 5.577182633914171 0.7758513819677906 SEEDNEIES(ph)EEEVQPK ddPTM_PC-9_Lapatinib_30min_R1 2 SEEDNEIESEEEVQPK 16 0 P52701-2;P52701;P52701-3;A0A087WWJ1;A0A494C0M1;C9J7Y7 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 SEEDNEIES(1)EEEVQPK;SEEDNEIES(1)EEEVQPK 198.61 4.8244e-12 35182000.0 79486.0 98552.0 78004.0 80689.0 90880.0 85007.0 101473.0 113229.0 89739.0 84591.0 True False 78352.51506405264 98323.80889901699 71590.81222414742 86623.13823061345 85534.61707695446 81371.44877099556 106726.77542879774 118490.03270278686 79631.64882643647 99212.44163957781 0.7897448522504286 0.9910431320318769 0.7215910730654614 0.8731076143181801 0.8621359948753947 0.8201738353200136 1.0757398332813766 1.1943061852387558 0.8026377288014434 1.0 16.59823343127252 -7.258624745004274 24.893537979786913 1.0343631225848238 0.8464212375842659 0.3700085142040853 0.11114388103268022 235.66514470542188 2084311.1077590308 0.04213305146701442 0.031129084714734877 5.512838310823796e-08 7.258624745004274 -0.18794188500055786 SEEEFIHINNK ddPTM_PC-9_Lapatinib_30min_R1 1 SEEEFIHINNK 11 0 Q15046;Q15046-2;J3KRL2;H3BVA8 Q15046 KARS Lysine--tRNA ligase 0 90.05 0.007510500000000001 4255700.0 61922.0 71509.0 77378.0 76867.0 80980.0 70029.0 80823.0 65439.0 74906.0 79791.0 False True 61038.98092489596 71343.42530399995 71016.27952771758 82520.05560079498 76216.91561280559 67034.02291557218 85007.61947002372 68479.53483681449 66469.29748485108 93582.76803517561 0.6522459444879084 0.7623564337954141 0.7588606430301804 0.8817868645408905 0.8144332254006144 0.716307332247061 0.9083682953048718 0.7317536793854463 0.7102728299281209 1.0 16.513955281591983 -12.088562242904377 2.217716986991654 5.025908779237176 0.7759712417936871 0.4574543791059571 0.07471452230708506 4537269.179407092 366053.3181164076 91672062.14906757 0.019921489742178496 8.155258979244923e-13 12.088562242904377 -4.249937537443489 SEEEIDFLR ddPTM_PC-9_Lapatinib_30min_R1 2 SEEEIDFLR 9 0 B0QY90;B0QY89;Q9Y262-2;Q9Y262 B0QY90 EIF3L Eukaryotic translation initiation factor 3 subunit L 0 ; 119.21 0.008068200000000001 2430980.0 15157.8 16034.4 14836.7 15217.6 18483.0 15087.3 14171.4 12796.7 15319.3 12708.0 False True 14941.64699239991 15997.273331950599 13616.883797318213 16336.753068425445 17395.866278976122 14442.051349214076 14905.125750807263 13391.281398650117 13593.879114619387 14904.560867654387 1.0024882400142365 1.073313965704793 0.9136051654409578 1.0960908686601547 1.167150540927933 0.9689685913897644 1.0000379000198591 0.8984686981091565 0.9120616994574179 1.0 13.863466249451486 -6.975052916815333 24.97582482147997 0.9499413774197989 1.0488537992405762 0.32724634094250193 0.06809225475879842 278.6842696754808 279004.535802164 0.02513298049457164 0.022164462595055032 1.059124667771822e-07 6.975052916815333 0.09891242182077731 SEEEQS(ph)S(ph)SSMKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEEEQSSSSMKK 12 1 A0A0G2JNQ3;B2RXH8;O60812 A0A0G2JNQ3 HNRNPCL2;HNRNPCL1 Heterogeneous nuclear ribonucleoprotein C-like 2;Heterogeneous nuclear ribonucleoprotein C-like 1 2 SEEEQS(0.624)S(0.504)S(0.479)S(0.392)MKK 79.089 0.011773 0.0 3538.6 3124.7 5357.4 4390.0 5234.9 6545.7 3757.7 5141.7 4569.6 3634.0 True False 4137.615089464219 3434.899565577118 5485.140734052645 4144.042532572029 4209.15892404408 6202.431968953716 3401.743452607929 5006.735823081471 4636.421755166136 4292.8154332718295 0.9638464904396501 0.8001507679446542 1.2777490249265313 0.9653437463100035 0.9805124374601892 1.444840120747154 0.7924271391316823 1.1663058663729964 1.0800421837918204 1.0 12.067708431072914 -5.241183447654658 24.826405305678964 1.08825325909978 0.8819986236117491 0.18284256274027555 0.17453859683539533 1225.5447651619202 1502066.519830686 0.04218900560588884 0.11133339274149197 5.738740044231318e-06 5.241183447654658 -0.2062546354880309 SEEEQS(ph)SSSVKKDETNVK ddPTM_PC-9_AZD4547_30min_R2 1 SEEEQSSSSVKKDETNVK 18 2 B4DY08;B2R5W2;G3V4W0;G3V5V7;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 S(0.002)EEEQS(0.249)S(0.249)S(0.249)S(0.249)VKKDETNVK 76.158 0.015493999999999999 6035400.0 15073.0 16908.0 13491.0 13131.0 14241.0 16808.0 15576.0 17615.0 23247.0 18638.0 True False 19865.90046212347 22373.180346039004 13312.100525137192 10103.850821927665 12263.882967553374 15756.993102941315 16962.23382528976 14893.006502431272 24475.78896030887 17985.48929296569 1.1045515714656275 1.243957280316493 0.7401578188002754 0.5617779231549395 0.6818765265591026 0.8760947698600581 0.9431066093889292 0.828056788438671 1.3608631136814056 1.0 14.134545787893083 -8.244090905454089 24.445101833558688 1.1804315702718757 0.8661902768913786 0.26754805800592396 0.20362371093653545 766.3443927500563 1079832.917703275 0.1521530906154301 0.05717893774588568 5.700449393855772e-09 8.244090905454089 -0.3142412933804971 SEEEQSS(ph)S(ph)SMKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEEEQSSSSMKK 12 1 A0A0G2JNQ3;B2RXH8;O60812 A0A0G2JNQ3 HNRNPCL2;HNRNPCL1 Heterogeneous nuclear ribonucleoprotein C-like 2;Heterogeneous nuclear ribonucleoprotein C-like 1 2 SEEEQS(0.098)S(0.609)S(0.709)S(0.584)MKK 96.334 0.013986000000000002 3454800.0 14946.0 13309.0 11847.0 17004.0 16313.0 15789.0 15497.0 17184.0 15376.0 12938.0 True False 17476.062603044193 14630.229563883202 12129.477409997702 16051.321007711793 13116.584753850326 14960.99704505404 14029.011971435997 16732.938207953004 15600.844911465882 15283.556982848348 1.1434551932286665 0.9572529209202852 0.7936292201880593 1.0502346427422002 0.8582154513226299 0.9788949694003632 0.9179153771062432 1.0948327164109242 1.0207600841200517 1.0 13.899692724252903 -7.754553257120866 24.98916672316017 1.0433473036851828 0.9514238646536853 0.13525998715390086 0.09336913478416249 280.4545040761722 1017756.7692771525 0.04430059045825445 0.02485234425452538 1.75973285619661e-08 7.754553257120866 -0.09192343903149747 SEEEQSS(ph)S(ph)SMKK ddPTM_PC-9_Lapatinib_30min_R1 1 SEEEQSSSSMKK 12 1 A0A0G2JNQ3;B2RXH8;O60812 A0A0G2JNQ3 HNRNPCL2;HNRNPCL1 Heterogeneous nuclear ribonucleoprotein C-like 2;Heterogeneous nuclear ribonucleoprotein C-like 1 2 SEEEQS(0.295)S(0.576)S(0.616)S(0.513)MKK 81.676 0.041943 5433200.0 21153.0 16588.0 19616.0 20226.0 18332.0 19830.0 15899.0 16916.0 17732.0 12218.0 True False 20851.35434101488 16549.591505163684 18003.24819994973 21713.48751195807 17253.7478020987 18981.917125987762 16722.172425595527 17701.979114894108 15734.83543376205 14329.865020538351 1.4550977494295705 1.1549021209511672 1.256344576459477 1.5152611333628825 1.2040411949009764 1.324640329743639 1.166945564499623 1.2353207158282828 1.098044916069343 1.0 13.806737399818239 -8.177174231559327 0.6714408627294609 0.9989612895965946 1.3216168834374702 0.5039988721524389 0.1047215602682934 0.5945601809567806 0.5990702812291014 0.10060218017858036 0.04464448984052321 6.650063134569116e-09 8.177174231559327 0.3226555938408756 SEEEQSS(ph)SSVKKDETNVK ddPTM_PC-9_Lapatinib_30min_R1 1 SEEEQSSSSVKKDETNVK 18 2 B4DY08;B2R5W2;G3V4W0;G3V5V7;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 SEEEQS(0.099)S(0.3)S(0.3)S(0.3)VKKDETNVK 116.39 0.00034001 5487400.0 13322.0 11239.0 10723.0 9978.3 10561.0 10099.0 9471.5 8553.4 7619.0 9207.2 True False 13132.025837044413 11212.976786022109 9841.39633197701 10712.137468633007 9939.822743724872 9667.089311918833 9961.88792559457 8950.822189721875 6760.8679883731775 10798.65225217717 1.2160800746590206 1.0383681707836647 0.9113541303261097 0.9919883721112772 0.9204688244054581 0.8952125771037588 0.9225121517906186 0.8288832699392886 0.6260844252124227 1.0 13.398563644675967 -1.5228787452803538 0.4198998556139672 0.8401993369652045 7.557975099560303 0.5629343654987492 0.09497048328016894 58.6180847391618 0.7512500919446339 0.0650722410005008 330.73900547675294 0.029999999999998875 1.5228787452803538 6.717775762595099 SEEEQSSSS(ph)VKKDETNVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEEEQSSSSVKKDETNVK 18 2 B4DY08;B2R5W2;G3V4W0;G3V5V7;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 SEEEQS(0.183)S(0.183)S(0.183)S(0.451)VKKDETNVK 76.015 0.015676 4741200.0 5723.2 6501.5 4345.7 7044.4 7783.9 4959.4 6986.2 4238.2 4519.1 6024.4 True False 6692.0247216474345 7146.925953083372 4449.317969159027 6649.72510625294 6258.700672193689 4699.320333475266 6324.416560292073 4126.951740744089 4585.183288202749 7116.576030875837 0.9403433185584679 1.004264680385042 0.6252048667582982 0.9343995029916877 0.8794539178728383 0.6603344520014803 0.8886881181136944 0.5799069275504086 0.6442962554337315 1.0 12.79696757481383 -6.741598262172519 24.862394476666264 0.7367670223984913 0.8730482671651653 0.14017887416716202 0.14776577161498405 418.72181271350206 524688.3212132901 0.04806896286449138 0.04800688273926431 1.8130164217798348e-07 6.741598262172519 0.13628124476667391 SEEEQSSSS(ph)VKKDETNVK ddPTM_PC-9_Lapatinib_30min_R1 1 SEEEQSSSSVKKDETNVK 18 2 B4DY08;B2R5W2;G3V4W0;G3V5V7;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 SEEEQS(0.148)S(0.148)S(0.148)S(0.554)VKKDETNVK 67.685 0.035794 3837500.0 22857.0 18789.0 12987.0 16983.0 19959.0 15757.0 16969.0 15021.0 16208.0 13424.0 True False 22531.05498853957 18745.495224892726 11919.258991269731 18231.986473627217 18785.050860903768 15083.109841361023 17847.57179004533 15718.930496856488 14382.484362193507 15744.320513644363 1.4310592171325323 1.1906195131538055 0.7570513431138707 1.1580040216932188 1.1931318880750836 0.9580032258800677 1.133587935698987 0.9983873539181402 0.913503021596222 1.0 13.942543875177817 -4.927449755222084 4.208861864098912 1.0245194749825473 1.4147246263299085 0.52550430352104 0.12259567701936488 0.17362023655932624 5.732422120130895 0.03100059777755272 0.15037710910690777 1.1818170324480058e-05 4.927449755222084 0.3902051513473612 SEEHS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 2 SEEHSPPR 8 0 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 1 S(0.001)EEHS(0.999)PPR;S(0.011)EEHS(0.989)PPR 67.207 0.026611000000000003 20526500.0 10389.3 11461.0 16299.599999999999 20765.5 20828.5 16688.0 13058.4 15008.8 13671.6 16446.4 True False 13692.881289135506 15165.544117929565 16083.456654030555 15978.33479877686 17936.822301080363 15644.496721911273 14220.5723025272 12689.534827913161 14394.252864875425 15870.61654189457 0.8627819374874082 0.9555737219090522 1.0134109542357186 1.0067872761337242 1.1301906421676506 0.985752297688852 0.8960314972634079 0.7995615541725096 0.9069750268918726 1.0 13.954070554644805 -7.261950863797959 4.9917620918721575 0.8828629717564079 0.999165647806372 0.24165545999558335 0.07700840444005014 0.22984865623822348 17.9830979283512 0.032983178633375736 0.023484790791636286 5.4707785593788145e-08 7.261950863797959 0.11630267604996403 SEEHS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SEEHSPPR 8 0 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 1 SEEHS(1)PPR;SEEHS(1)PPR 105.2 0.0021796 14389000.0 73728.0 82219.0 126784.0 129708.0 149576.0 121702.0 105010.0 82762.0 101227.0 89570.0 True False 86208.69420562296 90381.15895355861 129807.01139099734 122440.88127900969 120267.65654030039 115319.73287587336 95062.69259343723 80589.58519358744 102707.2533723308 105808.33196427012 0.8147628131472135 0.8541969925778525 1.2268127564361493 1.1571950810107858 1.1366558219716851 1.0898927403450145 0.8984424083496417 0.7616563241995093 0.9706915463615237 1.0 16.691093712571544 -7.27416072793803 18.96609448307321 0.8878349456474856 1.0551549116947547 0.19621503774116023 0.1346773763598619 49.45744281514346 73730.04435213604 0.060942818269411 0.04167193001343733 5.3191136788793695e-08 7.27416072793803 0.16731996604726918 SEEHS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 1 SEEHSPPR 8 0 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 1 SEEHS(1)PPR 101.38 0.0026089000000000004 8187200.0 33837.0 28253.0 46702.0 33916.0 49024.0 47800.0 36426.0 43167.0 60474.0 34358.0 True False 33354.47817505419 28187.58191435915 42862.34183493332 36410.2957804593 46140.50470489237 45755.7054272423 38311.96004621315 45172.69640888119 53662.78130054856 40296.734520842736 0.8277216149562244 0.6995003999587026 1.0636678714689294 0.9035544992268978 1.1450184550568745 1.1354693121244355 0.9507460220231245 1.12100141478006 1.3316905684452542 1.0 15.298375313055429 -5.481776048984584 0.9499585791433905 1.1155035374600464 0.7182695384139796 0.5179838582429643 0.11957278123216268 0.6987029180794705 0.9855606337388122 0.04529890892675231 0.22909526007351233 3.2977972461925246e-06 5.481776048984584 -0.3972339990460668 SEEIS(ph)ESESEETNAPK ddPTM_PC-9_AZD4547_30min_R2 1 SEEISESESEETNAPK 16 0 P54259 P54259 ATN1 Atrophin-1 1 S(0.001)EEIS(0.967)ES(0.023)ES(0.008)EET(0.001)NAPK 79.317 0.009020100000000001 14471000.0 20076.0 18779.0 22092.0 29976.0 26328.0 20702.0 22273.0 22924.0 18387.0 22777.0 True False 26459.750393258884 24848.944506639848 21799.045645343616 23065.496324583328 22672.811654360332 19407.500667366206 24255.2538514817 19381.622541114637 19358.899282195533 21979.58416277924 1.203833075152826 1.1305466164696443 0.9917860812971452 1.049405491649064 1.0315396090502487 0.8829785187761349 1.1035356115861434 0.8818011477185245 0.8807673129220689 1.0 14.423876471388402 -1.5228787452816428 0.3982023069596911 0.9428103550825402 5.308240205416085 0.5672762019698288 0.06969602178211598 52.262243092177044 0.6952152950552491 0.05010420422875946 178.7282052649287 0.02999999999990984 1.5228787452816428 4.365429850333545 SEEIS(ph)ESESEETNAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEEISESESEETNAPK 16 0 P54259 P54259 ATN1 Atrophin-1 1 SEEIS(0.96)ES(0.038)ES(0.001)EETNAPK 141.06 2.2698000000000002e-05 5957800.0 13212.0 19390.0 15870.0 18175.0 18788.0 17916.0 17584.0 16005.0 16684.0 16087.0 True False 15448.53065110531 21314.91105595426 16248.400987310153 17156.71367414503 15106.626270786484 16976.45342068454 15918.316222864476 15584.885708699243 16927.97193697299 19003.445755378063 0.8129331306525451 1.121634009449157 0.8550239359991743 0.9028211985865564 0.7949414261627389 0.8933355371027975 0.8376542037572065 0.8201084113542223 0.890784342738595 1.0 14.2139734151307 SEEIS(ph)ESESEETNAPK ddPTM_PC-9_Lapatinib_30min_R1 2 SEEISESESEETNAPK 16 0 P54259 P54259 ATN1 Atrophin-1 1 SEEIS(0.905)ES(0.092)ES(0.002)EETNAPK;S(0.001)EEIS(0.999)ESESEETNAPK 228.11 7.720399999999999e-29 27001000.0 131609.0 117758.0 140307.0 118329.0 134878.0 136819.0 127371.0 132405.0 132993.0 112022.0 True False 129732.23152586517 117485.33858602984 128771.5000606827 127031.30939397264 126944.74122035057 130967.57031066665 133965.64714891056 138557.01966821696 118013.927861624 131384.8534400679 0.9874215187601012 0.8942076313204671 0.9801091730822891 0.9668641861515554 0.9662052960941747 0.9968239632006622 1.0196430078602623 1.0545889883069413 0.8982308445125059 1.0 17.003439440154615 -6.218107924454498 1.205614794464934 0.9979467327370479 0.9464481325675436 0.12952327838324373 0.04391384156993419 0.8188397171760665 2.4390441821782263 0.017432886965833682 0.026566152652463454 6.051904630643136e-07 6.218107924454498 -0.05149860016950436 SEEIS(ph)ESESEETNAPKK ddPTM_PC-9_Lapatinib_30min_R1 2 SEEISESESEETNAPKK 17 1 P54259 P54259 ATN1 Atrophin-1 1 S(0.039)EEIS(0.949)ES(0.012)ESEETNAPKK;S(0.022)EEIS(0.972)ES(0.005)ES(0.001)EETNAPKK 103.73 0.00038331 8898900.0 28479.0 20018.9 20492.5 16503.1 18584.1 20003.3 17108.2 22213.0 23172.0 17431.6 True False 28072.884237591017 19972.547467007556 18807.685753337566 17716.793026727737 17491.019775746383 19147.805488969785 17993.97888493449 23245.097072543333 20562.12534802247 20444.62883385303 1.3731178230590726 0.9769092718345769 0.919932854060674 0.866574451935834 0.8555312946931106 0.9365689954353237 0.880132333590686 1.1369781893057984 1.0057470602731062 1.0 14.319434250952721 -4.761652908122709 4.788613009177817 0.9457857268279868 1.4038177887597378 0.7178435436748165 0.07910664513304595 0.10676014327578907 5.971195339925248 0.021590161552083154 0.16667335692966323 1.7311993958893938e-05 4.761652908122709 0.45803206193175106 SEEISES(ph)ESEETNAPK ddPTM_PC-9_AZD4547_30min_R2 1 SEEISESESEETNAPK 16 0 P54259 P54259 ATN1 Atrophin-1 1 SEEIS(0.245)ES(0.754)ES(0.001)EETNAPK 245.39 6.1158999999999995e-47 8909200.0 30819.0 26132.0 33844.0 37175.0 38977.0 30982.0 29866.0 33590.0 27198.0 26043.0 True False 40618.800924977375 34578.65796088783 33395.20644672323 28604.87809802458 33565.716341993415 29044.690642273206 32524.016141891603 28399.437321411653 28635.63075418253 25131.24249687225 1.6162671197030012 1.3759231349262326 1.3288322871771852 1.1382198115188553 1.3356170649410146 1.1557204402403904 1.2941666591271574 1.130045095261253 1.1394434938004527 1.0 14.617194379847334 -1.5228787452803376 0.3876270996425895 1.1359077248527227 7.889726382327486 0.7444209110417629 0.08398477364173604 35.854980141045225 0.4844869486095142 0.06103132225287483 183.07602368066088 0.029999999999999995 1.5228787452803376 6.753818657474763 SEEISES(ph)ESEETNAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEEISESESEETNAPK 16 0 P54259 P54259 ATN1 Atrophin-1 1 S(0.001)EEIS(0.191)ES(0.404)ES(0.404)EETNAPK 138.81 1.6693e-05 12179000.0 32137.0 34503.0 30325.0 35424.0 46256.0 36841.0 37943.0 35693.0 36409.0 31368.0 True False 37577.15936531724 37928.22981761683 31048.063008202927 33439.30812615754 37192.468851474354 34908.99310512609 34348.76435646877 34756.09656985954 36941.41274593923 37054.77009104861 1.0140977605038446 1.023572126460966 0.8378965226855709 0.9024292430905013 1.0037160872969229 0.9420917474147038 0.9269728100341517 0.9379655165707164 0.996940816396085 1.0 15.177371653355387 -8.269313218863676 22.3116986538963 0.9984704698968423 0.9467634665373228 0.12376967038531339 0.052905757758941546 334.36724581588896 947424.9081581046 0.049957972247571585 0.0140006811283863 5.378817152615659e-09 8.269313218863676 -0.0517070033595195 SEEKISDS(ph)EGFK ddPTM_PC-9_Lapatinib_30min_R1 1 SEEKISDSEGFK 12 1 P23246;P23246-2 P23246 SFPQ Splicing factor, proline- and glutamine-rich 1 SEEKIS(0.122)DS(0.878)EGFK 104.41 0.0068241 0.0 12721.0 14180.0 10814.0 15032.0 15988.0 13415.0 13756.0 13723.0 12730.0 15511.0 True False 12539.596207254312 14147.1670812166 9924.91466324716 16137.503425281993 15047.617273617401 12841.271721892374 14468.218371375067 14360.620678274516 11296.213347157176 18192.055682891652 0.6892896781888657 0.7776563203091453 0.5455631203119526 0.8870632163059053 0.8271532110452271 0.7058724943310659 0.7953042044050804 0.78938966154219 0.6209421048430755 1.0 14.151020954751345 -11.830509168217372 2.3045837079200338 2.317966352889257 0.7424324786838175 0.4016463262642468 0.09592446125125978 7569454.877769978 656849.4686299246 52423897.77078544 0.023614821596006117 1.4773752929805902e-12 11.830509168217372 -1.5755338742054397 SEEPAGQILSHLS(ph)SELK ddPTM_PC-9_AZD4547_30min_R2 2 SEEPAGQILSHLSSELK 17 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SEEPAGQILS(0.001)HLS(0.759)S(0.241)ELK;SEEPAGQILS(0.006)HLS(0.91)S(0.084)ELK 108.69 0.00028759 9626800.0 32128.0 33081.0 32852.0 38292.0 35665.0 48098.0 46006.0 50923.0 44825.0 39011.0 True False 42344.03569608593 43773.7863157864 32416.361014884544 29464.371005502555 30713.530372711964 45090.424456524954 50100.44487456862 43054.020444127564 47194.35798794877 37645.23676402426 1.1248178876258812 1.1627974766151266 0.8611012654292375 0.7826852355902895 0.8158676372587835 1.1977723699593172 1.330857478427316 1.1436777702849308 1.2536608093019128 1.0 15.200179712397475 -6.782867384565087 24.145168689711678 1.2032777284901865 0.9471329566803267 0.4150312659932075 0.13909621651422246 165.76793086405652 186786.24137776517 0.053309809807218854 0.04706523662034764 1.6486657484784992e-07 6.782867384565087 -0.25614477180985984 SEEPAGQILSHLS(ph)SELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEEPAGQILSHLSSELK 17 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SEEPAGQILS(0.001)HLS(0.923)S(0.077)ELK 115.02 9.0122e-05 3646000.0 12019.0 17384.0 12720.0 17004.0 16539.0 15107.0 17056.0 14757.0 13229.0 12969.0 True False 14053.57931392936 19109.76863314641 13023.293040868639 16051.321007711793 13298.301676204906 14314.762325646423 15440.33220525344 14369.644386333946 13422.44909819083 15320.177037452493 0.9173248637775697 1.2473595172190037 0.8500745787095819 1.0477242507362616 0.8680253265804432 0.9343731662272452 1.0078429359861318 0.9379555047702892 0.8761288505594693 1.0 13.903145348455858 -5.2815817114482435 24.99954901739228 0.941510541059905 1.0823422592206964 0.26047137756110494 0.09574067983270394 878.8216189425088 1090743.9651954388 0.023039844049763645 0.04805575736560647 5.228995746459004e-06 5.2815817114482435 0.14083171816079143 SEEPAGQILSHLS(ph)SELK ddPTM_PC-9_Lapatinib_30min_R1 1 SEEPAGQILSHLSSELK 17 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SEEPAGQILSHLS(0.687)S(0.313)ELK 146.34 5.1951000000000005e-05 3389500.0 16050.0 15873.0 18737.0 17110.0 21757.0 20060.0 19622.0 19604.0 17981.0 18125.0 True False 15821.124056790477 15836.247043734222 17196.516186911613 18368.326477286784 20477.296035907795 19202.08056214395 20637.931148816628 20514.873407920553 15955.79043167582 21257.882099955597 0.7442474270201886 0.7449588331175898 0.8089477637542986 0.8640713308559158 0.9632801583724357 0.9032922692794527 0.9708366549299723 0.9650478496144921 0.7505823184384462 1.0 14.375710249415015 -5.716648473256775 1.798315302483892 0.9249474401388093 0.7434993737607948 0.5528352810630764 0.065300727372204 0.2631781488484139 1.7259021663599023 0.019844341258223142 0.04322741941282384 1.920222378668618e-06 5.716648473256775 -0.18144806637801447 SEEPAGQILSHLSS(ph)ELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEEPAGQILSHLSSELK 17 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SEEPAGQILSHLS(0.384)S(0.616)ELK 98.292 0.00077652 4101100.0 12033.0 14484.0 14124.0 16355.0 20911.0 12773.0 15218.0 13558.0 14168.0 12140.0 True False 14069.949237416757 15921.875798578738 14460.769725568287 15438.682373625408 16813.6396608695 12103.161394418605 13776.440871221088 13202.116865888429 14375.180196777359 14340.885899812882 0.9811073971099888 1.1102435309653 1.008359582984826 1.0765501156261796 1.1724268485455895 0.8439619057687731 0.9606408535333819 0.9205928391118912 1.0023913653036542 1.0 13.807846527981843 -6.763057705707439 24.999938542155625 0.941499673361865 1.0689564181923445 0.48237848837444786 0.06426903262544578 37.12091043271783 573436.5332307309 0.0214783277175766 0.019943907029679363 1.7256085911712835e-07 6.763057705707439 0.12745674483047953 SEEPAGQILSHLSS(ph)ELK ddPTM_PC-9_Lapatinib_30min_R1 1 SEEPAGQILSHLSSELK 17 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SEEPAGQILSHLS(0.317)S(0.683)ELK 136.57 2.9075e-05 3320700.0 17131.0 18270.0 16119.0 14616.0 15730.0 18893.0 16811.0 18382.0 15955.0 15877.0 True False 16886.70879855936 18227.696937505447 14793.758041139363 15690.909397546684 14804.79232636988 18084.99043173407 17681.39132314527 19236.094826790242 14157.979886401616 18621.318295227302 0.906848190382282 0.9788617888657893 0.7944527775421274 0.8426315016358594 0.7950453395216595 0.9711981796889915 0.9495241444681746 1.0330146621101746 0.7603102885594489 1.0 14.184667591579501 -6.782844446812236 24.97795546545176 0.945292548961818 0.8649702426203099 0.18134723396110108 0.08407247438946236 431.0985642239487 503053.152483089 0.029645504064747922 0.02616910548024937 1.6487528269188922e-07 6.782844446812236 -0.08032230634150817 SEES(ph)PVYSNSSVR ddPTM_PC-9_AZD4547_30min_R2 3 SEESPVYSNSSVR 13 0 H0Y8J2;Q03188 H0Y8J2 CENPC Centromere protein C 1 S(0.018)EES(0.975)PVYS(0.007)NSSVR;S(0.007)EES(0.993)PVYSNSSVR;S(0.217)EES(0.783)PVYSNSSVR 219.84 8.4151e-15 32952300.0 52794.0 58616.0 75963.0 104787.0 81999.0 77904.0 66348.0 80835.0 67244.0 74816.0 True False 69581.39381658233 77562.47570164558 74955.6809866576 80629.97609301144 70614.8542557692 73032.65056470355 72252.84346689298 68343.80815350743 70798.38055865312 72196.71461221795 0.9637750719034378 1.0743214025492454 1.0382145695861449 1.1168094909316872 0.9780895797690349 1.0115785871556007 1.0007774433362586 0.9466332162148208 0.9806316109939969 1.0 16.13964556679342 -6.321274102181404 24.999988783737848 0.9856059837428482 1.0494215593492067 0.375399008641608 0.03915879992126687 259.7270342961914 108517.76637940317 0.012026898587211307 0.013637221716158122 4.77227979204344e-07 6.321274102181404 0.06381557560635842 SEES(ph)PVYSNSSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SEESPVYSNSSVR 13 0 H0Y8J2;Q03188 H0Y8J2 CENPC Centromere protein C 1 S(0.316)EES(0.662)PVYS(0.021)NSS(0.001)VR;S(0.007)EES(0.992)PVYS(0.001)NSSVR 175.6 0.00016326 15971800.0 33845.0 34017.0 33777.0 33636.0 46297.0 37085.0 33883.0 30879.0 36194.0 29756.0 True False 39574.290030779506 37393.98294947891 34582.37177998585 31751.48396938335 37225.435195795304 35140.19731558863 30673.356948323304 30068.458969004947 36723.26877767926 35150.527251633626 1.1258519608390878 1.0638242402961684 0.9838365021502951 0.9033003613881124 1.0590292125437535 0.9997061228706173 0.8726286444792305 0.8554198562585575 1.0447430422533004 1.0 15.101258709177621 -5.127557648520379 2.1779248588345177 0.956969539995346 1.1263187164198958 0.4051329275344513 0.06512491890332972 0.3762283828754566 3.102508129652215 0.01871788330434243 0.0924873839303589 7.454909085315588e-06 5.127557648520379 0.16934917642454983 SEES(ph)PVYSNSSVR ddPTM_PC-9_Lapatinib_30min_R1 1 SEESPVYSNSSVR 13 0 H0Y8J2;Q03188 H0Y8J2 CENPC Centromere protein C 1 S(0.007)EES(0.993)PVYSNSSVR 211.82 1.2437e-10 14665000.0 28939.0 26964.0 29628.0 28438.0 30646.0 30668.0 28513.0 26552.0 26559.0 22203.0 True False 28526.32455323735 26901.566514663235 27192.100207387364 30529.425386387025 28843.46253235418 29356.401130599745 29989.263624819512 27785.702852841605 23567.645741331282 26040.758966362147 1.0954490454785095 1.0330561620501548 1.0442130447316242 1.1723707986323695 1.1076275683674348 1.1273250971110536 1.1516278639788418 1.067008180857304 0.9050291418838644 1.0 14.668483876480428 -8.11279829555323 5.051022836080927 0.955249660601869 1.1034595926924389 0.6314191034282997 0.04569286830311337 0.15040912048242477 5.554576933948477 0.03439682772905347 0.012445301303773288 7.712615919025286e-09 8.11279829555323 0.14820993209056987 SEETLDEGPPK ddPTM_PC-9_Lapatinib_30min_R1 2 SEETLDEGPPK 11 0 Q00688 Q00688 FKBP3 Peptidyl-prolyl cis-trans isomerase FKBP3 0 ; 147.95 0.00099246 7580800.0 49890.0 58633.0 74014.0 64186.0 60637.0 55229.0 67509.0 58623.0 61578.0 62376.0 False True 49178.55945129448 58497.23889090078 67928.85462230229 68906.45255821914 57070.45087692884 52866.98441508712 71004.2856959261 61346.838593783265 54642.43719491313 73157.6084892044 0.6722275436129324 0.7996056746378335 0.9285275451879527 0.941890446957235 0.780102740583032 0.7226450605324053 0.9705659761472921 0.8385571898900439 0.7469139344949544 1.0 16.15872029393135 -12.039308600022135 2.2376019485429524 3.4476505352209306 0.8289706790038482 0.24008759203915986 0.09415987271464751 4765510.992292821 504138.11772955937 59142589.13011627 0.024849067049303477 9.134639236071794e-13 12.039308600022135 -2.6186798562170823 SEETLLT(ph)PER ddPTM_PC-9_AZD4547_30min_R2 1 SEETLLTPER 10 0 Q6P4F7-3;Q6P4F7;H3BQ41 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 1 SEETLLT(1)PER 141.71 0.00030681 15855000.0 28740.0 23450.0 40540.0 53085.0 40053.0 32769.0 29537.0 45192.0 25562.0 39338.0 True False 37878.72217086374 31029.75391025638 40002.413111634574 40847.07340507426 34492.33231510537 30719.94924977892 32165.73577924907 38208.61480884893 26913.1551341427 37960.7885935553 0.997838126505478 0.817415945766848 1.0537824579973527 1.0760333206568047 0.908630552552884 0.8092547701971167 0.8473410846030193 1.0065284791089852 0.7089724984984063 1.0 15.212222342619594 -6.511028291618209 24.356527380221483 0.8715580698055199 0.9806919979625378 0.20652836546920095 0.10344168136581748 680.6195450681266 1398897.7542539716 0.03258140155096634 0.03499616164375535 3.0829871060322267e-07 6.511028291618209 0.10913392815701795 SEETLLT(ph)PER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SEETLLTPER 10 0 Q6P4F7-3;Q6P4F7;H3BQ41 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 1 SEET(0.001)LLT(0.999)PER;SEETLLT(1)PER 106.67 0.005582500000000001 19854000.0 62859.0 65384.0 69962.0 63857.0 63966.0 60634.0 62054.0 59009.0 61605.0 54833.0 True False 73499.78717815837 71874.89141219773 71630.15941236257 60279.29931718732 51432.32148377307 57454.24629994339 56175.795887945394 57460.0762752036 62505.856579790314 64773.78884221081 1.1347149594291006 1.1096292604912341 1.1058510038196763 0.9306125269903219 0.7940298445265013 0.88699838818912 0.8672612316193181 0.8870883933496088 0.9649868827660338 1.0 15.983122514305693 -5.793999276979332 4.037632464075128 0.8899253264161296 1.119515343974931 0.772079770753309 0.05290603463052256 0.0901366072092051 3.171404470781217 0.014875723371464575 0.024153945327291784 1.606943928277596e-06 5.793999276979332 0.22959001755880137 SEEVPAFGVAS(ph)PPPLTDTPDTTANAEGDLPTTMGGPLPPHLALK ddPTM_PC-9_AZD4547_30min_R2 5 SEEVPAFGVASPPPLTDTPDTTANAEGDLPTTMGGPLPPHLALK 44 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 1 SEEVPAFGVAS(0.993)PPPLT(0.003)DT(0.003)PDT(0.001)TANAEGDLPTTMGGPLPPHLALK;SEEVPAFGVAS(0.849)PPPLT(0.069)DT(0.061)PDT(0.016)T(0.004)ANAEGDLPTTMGGPLPPHLALK;SEEVPAFGVAS(0.88)PPPLT(0.062)DT(0.053)PDT(0.004)T(0.001)ANAEGDLPTTMGGPLPPHLALK;SEEVPAFGVAS(0.93)PPPLT(0.029)DT(0.029)PDT(0.009)T(0.003)ANAEGDLPTTMGGPLPPHLALK;SEEVPAFGVAS(0.914)PPPLT(0.033)DT(0.038)PDT(0.012)T(0.004)ANAEGDLPTTMGGPLPPHLALK 104.93 2.5896e-31 32263200.0 194520.0 173034.0 254245.0 300504.0 259232.0 259908.0 222092.0 272791.0 227049.0 256154.0 True False 256373.31373265208 228963.85663570568 250873.54517926788 231227.44554051885 223242.1114700372 243655.91167297008 241857.7577507865 230637.41906356646 239050.34661027964 247186.12642721014 1.0371670831135715 0.9262811790658063 1.0149175797418533 0.9354386060522264 0.9031336616530385 0.9857183944533408 0.9784439007421692 0.9330516335894893 0.9670864221446251 1.0 17.915238247224636 -4.746035743791112 24.95093400914041 0.9588411867137571 1.0371673011277474 0.3164698180950182 0.033748349581180684 1019.1242437615034 1650691.6198538672 0.008221248721243588 0.1954199753348999 1.7945859207328442e-05 4.746035743791112 0.07832611441399029 SEEVPAFGVAS(ph)PPPLTDTPDTTANAEGDLPTTMGGPLPPHLALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SEEVPAFGVASPPPLTDTPDTTANAEGDLPTTMGGPLPPHLALK 44 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 1 S(0.002)EEVPAFGVAS(0.542)PPPLT(0.122)DT(0.127)PDT(0.127)T(0.026)ANAEGDLPT(0.026)T(0.026)MGGPLPPHLALK;SEEVPAFGVAS(0.953)PPPLT(0.038)DT(0.005)PDT(0.002)T(0.002)ANAEGDLPTTMGGPLPPHLALK;SEEVPAFGVAS(0.979)PPPLT(0.007)DT(0.008)PDT(0.003)T(0.003)ANAEGDLPTTMGGPLPPHLALK;SEEVPAFGVAS(0.783)PPPLT(0.087)DT(0.079)PDT(0.025)T(0.025)ANAEGDLPTTMGGPLPPHLALK;SEEVPAFGVAS(0.947)PPPLT(0.016)DT(0.016)PDT(0.016)T(0.006)ANAEGDLPTTMGGPLPPHLALK 89.645 3.1577e-17 53396400.0 199606.0 212771.0 219386.0 253511.0 281378.0 239385.0 256173.0 214679.0 220615.0 191621.0 True False 233395.35340179573 233893.4987254486 224616.9942660383 239307.60056375133 226244.0007888738 226831.2291867921 231906.4389080904 209043.9037212028 223841.07701242523 226360.37042899907 1.0310786864302437 1.033279360173217 0.9922982271160949 1.057197424223218 0.9994859098352563 1.002080128941743 1.0245010576214397 0.9235004489744472 0.9888704307569418 1.0 17.788261877880373 -7.728619856802236 24.9999970201355 0.9671390324160966 1.0193886164821397 0.4303785308749041 0.025828804809682537 152.95503768434313 116512.25446038983 0.011566348218284762 0.00667725061715164 1.868014070679137e-08 7.728619856802236 0.052249584066043187 SEEVPAFGVAS(ph)PPPLTDTPDTTANAEGDLPTTMGGPLPPHLALK ddPTM_PC-9_Lapatinib_30min_R1 2 SEEVPAFGVASPPPLTDTPDTTANAEGDLPTTMGGPLPPHLALK 44 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 1 SEEVPAFGVAS(0.947)PPPLT(0.008)DT(0.028)PDT(0.008)T(0.008)ANAEGDLPTTMGGPLPPHLALK;SEEVPAFGVAS(0.845)PPPLT(0.039)DT(0.039)PDT(0.039)T(0.039)ANAEGDLPTTMGGPLPPHLALK 81.986 5.872399999999999e-13 6709400.0 67495.0 67141.0 85744.0 61828.0 75591.0 77554.0 73139.0 65476.0 78907.0 56245.0 True False 66532.50892293274 66985.53913963072 78694.45930141161 66375.03737216174 71144.88599762393 74237.1962072039 76925.77954812454 68518.25399188974 70019.66273245339 65966.8733082484 1.0085745403157318 1.015442081461438 1.192939051903977 1.0061874095806556 1.0784941354606856 1.1253708487942145 1.1661274165393232 1.0386766956760147 1.0614367366673152 1.0 16.009454105358053 -5.04587839785238 24.998000500927745 1.087697829078359 1.0102909417039683 0.18305526249572923 0.060134349421325055 558.904164236016 304532.8477722 0.014955664540918609 0.039571716647107125 8.997494754797854e-06 5.04587839785238 -0.07740688737439072 SEFVILR ddPTM_PC-9_Lapatinib_30min_R1 1 SEFVILR 7 0 P54577;A0A0C4DGZ5 P54577 YARS Tyrosine--tRNA ligase, cytoplasmic;Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed;Tyrosine--tRNA ligase 0 97.473 0.019500999999999998 0.0 15473.0 15099.0 16486.0 14518.0 15186.0 18464.0 18884.0 17426.0 21175.0 15545.0 False True 15252.352182599308 15064.039193179802 15130.584717800326 15585.702150628264 14292.789336824733 17674.337761686227 19861.721119878366 18235.67557674065 18790.048517364743 18231.93253758951 0.8365735311466801 0.8262447857418113 0.8298947292946038 0.8548573837959631 0.7839426406036065 0.9694165840755682 1.0893919818389333 1.0002053012835268 1.030612003342188 1.0 14.15417987096642 -6.907228699444613 4.63389181733872 1.0301951246346082 0.8287895250642238 0.9177790793448966 0.029070454238518614 0.05282690430895375 1.9895718922743755 0.01005206264426863 0.008804572797452523 1.2381444080658504e-07 6.907228699444613 -0.2014055995703844 SEGDNYSATLLEPAASSLS(ph)PDHK ddPTM_PC-9_AZD4547_30min_R2 3 SEGDNYSATLLEPAASSLSPDHK 23 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 SEGDNYSATLLEPAAS(0.002)S(0.036)LS(0.961)PDHK;SEGDNYSATLLEPAAS(0.036)S(0.104)LS(0.86)PDHK;SEGDNYSATLLEPAAS(0.195)S(0.136)LS(0.669)PDHK 173.99 2.5656e-14 17036900.0 52044.3 52286.2 73540.0 78485.0 71944.0 87174.0 69201.0 89566.0 79904.0 74217.0 True False 68593.30481131113 69186.69163763091 72564.81154981753 60391.495831162414 61955.81744383536 81722.99599927453 75359.75493989953 75725.632721928 84127.56231275083 71618.6854198966 0.9577571049950466 0.966042468274766 1.0132106045283271 0.8432365866127008 0.8650789536360748 1.1410848372898341 1.052235942311273 1.0573446339869628 1.1746594037507856 1.0 16.128048417398034 -6.764003204799917 24.99999911040038 1.086597195832402 0.931025930796799 0.5972236227701184 0.06403935155454404 50.253710689902114 490022.3896587486 0.022791647982422447 0.021020886390309766 1.7218558688059007e-07 6.764003204799917 -0.15557126503560315 SEGDNYSATLLEPAASSLS(ph)PDHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SEGDNYSATLLEPAASSLSPDHK 23 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 SEGDNYSATLLEPAAS(0.002)S(0.086)LS(0.912)PDHK;SEGDNYSATLLEPAASS(0.003)LS(0.997)PDHK;SEGDNYSATLLEPAAS(0.023)S(0.283)LS(0.694)PDHK 203.73 2.8562e-30 13799500.0 50240.0 46694.3 62952.0 54835.0 70220.0 54341.0 60717.0 58994.0 49445.0 45510.0 True False 58744.63971476921 51329.801512122 64453.01442678949 51762.77272746865 56460.89507848771 51491.26229813679 54965.44620698715 57445.47000930979 50168.039584250204 53760.602743038246 1.092707981633937 0.9547847102359539 1.198889356483933 0.9628383999874647 1.0502280889289162 0.9577880393985105 1.022411271497601 1.0685421494227707 0.9331747976123043 1.0 15.71426169269435 SEGDNYSATLLEPAASSLS(ph)PDHK ddPTM_PC-9_Lapatinib_30min_R1 2 SEGDNYSATLLEPAASSLSPDHK 23 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 SEGDNYSATLLEPAAS(0.022)S(0.106)LS(0.871)PDHK;SEGDNYSATLLEPAASS(0.009)LS(0.991)PDHK 144.23 3.6908999999999997e-06 12865800.0 28195.0 36498.0 46631.0 43282.0 47402.0 48242.0 36638.0 42397.0 48111.0 41066.0 True False 27792.93412967024 36413.49112343043 42797.17918086542 46465.10266451943 44613.90755591766 46178.802117594656 38534.9363688892 44366.91939785795 42692.23254871002 48164.20338299457 0.5770454440752392 0.7560280989986645 0.8885681932814009 0.9647227484494211 0.9262876664055775 0.9587784884634695 0.8000741974795083 0.9211596223248792 0.8863892590359638 1.0 15.55567368392232 -4.915453174943733 1.8562836087622754 0.9166945462640579 0.5207548868240962 0.8186532282470161 0.05106819964395652 0.25160847310853884 1.1317661216751291 0.014223021377353857 0.16001968883334683 1.2149176042180403e-05 4.915453174943733 -0.3959396594399617 SEGFDTYR ddPTM_PC-9_AZD4547_30min_R2 2 SEGFDTYR 8 0 P12004 P12004 PCNA Proliferating cell nuclear antigen 0 ; 113.5 0.017107 22243000.0 120707.0 99928.0 161012.0 202458.0 174423.0 154379.0 155649.0 218700.0 139598.0 166798.0 False True 159089.31513842914 132227.77180145428 158876.87567662803 155784.436044919 150207.37721013714 144725.6567253078 169501.45946793348 184904.94022604148 146976.86528503476 160958.4527893601 0.9883874526715473 0.8215025027265607 0.9870676123144887 0.967854954773875 0.9332058963483424 0.8991491544386582 1.0530758498887491 1.1487743391023968 0.9131354255584049 1.0 17.296328816875757 -7.2682220493047005 24.660310372449825 1.0411442723883637 0.9318697126035033 0.2976794135189177 0.0711302010291895 505.5862935748042 1838192.7742015137 0.028440285853088717 0.01965923672213932 5.392348480274863e-08 7.2682220493047005 -0.10927455978486045 SEGFDTYR ddPTM_PC-9_Lapatinib_30min_R1 4 SEGFDTYR 8 0 P12004 P12004 PCNA Proliferating cell nuclear antigen 0 ;;; 110.81 0.017306000000000002 58501000.0 373071.0 386158.0 430314.0 377665.0 350956.0 374862.0 310445.0 311204.0 396405.0 323244.0 False True 367750.93912715756 385263.8748764767 394935.24398007634 405439.7439535087 330313.4580860438 358830.02610600204 326518.32308094855 325663.6739460569 351757.6945702933 379116.2947044431 0.9700214532162331 1.0162155524779706 1.0417258490246788 1.069433705743477 0.8712721207184048 0.9464906444755795 0.8612616435690278 0.8590073243882659 0.9278358632527827 1.0 18.53228094039956 -6.265011664963984 24.99967491466911 0.9032181180934945 1.0250093642486744 0.5815496941807781 0.04683453232145033 206.11177097725857 1442415.4051168696 0.014116700539843 0.016654379042792173 5.432357402169016e-07 6.265011664963984 0.12179124615517989 SEGS(ph)PVLPHEPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SEGSPVLPHEPAK 13 0 Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5;Q9UKE5-8;Q9UKE5-5;Q9UKE5-7;Q9UKE5-3 Q9UKE5-6 TNIK TRAF2 and NCK-interacting protein kinase 1 S(0.103)EGS(0.897)PVLPHEPAK;SEGS(1)PVLPHEPAK;S(0.015)EGS(0.985)PVLPHEPAK 132.31 5.7685e-05 117066000.0 195709.0 209528.0 201086.0 218014.0 213551.0 160523.0 176808.0 139638.0 152828.0 127544.0 True False 228838.66827105425 230328.55511768837 205880.65286290203 205799.38239092438 171707.2145386806 152104.89129540863 160059.46626093145 135972.65045869062 155062.82037782928 150666.71756225172 1.518840205545089 1.5287288317177439 1.3664640485569568 1.3659246429517071 1.1396492690413558 1.009545397659325 1.0623412313658382 0.9024730388946725 1.029177663698429 1.0 17.201001233702108 -6.183241845202125 0.999345275917155 0.9774629051224216 1.5293184055290283 0.9509491516282287 0.04857006658365848 0.10339816405600694 0.21591107982791857 0.02095295815091649 0.03577142521821101 6.557799809589526e-07 6.183241845202125 0.5518555004066067 SEGS(ph)PVLPHEPAK ddPTM_PC-9_Lapatinib_30min_R1 1 SEGSPVLPHEPAK 13 0 Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5;Q9UKE5-8;Q9UKE5-5;Q9UKE5-7;Q9UKE5-3 Q9UKE5-6 TNIK TRAF2 and NCK-interacting protein kinase 1 S(0.06)EGS(0.94)PVLPHEPAK 75.968 0.010069 24820000.0 416410.0 371500.0 370700.0 345570.0 328360.0 260300.0 222050.0 227670.0 261200.0 197190.0 True False 410471.9170397578 370639.81457489176 340222.4769433807 370984.37058772653 309046.5103805988 249167.5757889368 233546.66250100548 238248.3793501979 231780.90544206253 231274.0287608414 1.7748292760715623 1.6026002424948778 1.4710794755739824 1.6040900596381207 1.3362784919537216 1.0773694613440534 1.009826584300627 1.0301562204226944 1.0021916714295027 1.0 17.819243740057892 -6.547858955521957 1.5242415615283482 1.0036975503852938 1.6240081732142466 0.9428117808057139 0.0686677769762972 0.08814586710150686 0.4197493010192344 0.029147323839882215 0.031508946702465845 2.8323116875708327e-07 6.547858955521957 0.6203106228289528 SEHPPLCGR ddPTM_PC-9_AZD4547_30min_R2 1 SEHPPLCGR 9 0 Q15393;Q15393-3 Q15393 SF3B3 Splicing factor 3B subunit 3 0 68.37100000000001 0.036289999999999996 1793400.0 7368.8 6675.5 14718.0 29177.0 25486.0 16938.0 10257.0 21694.0 14668.0 19633.0 False True 9711.925119438438 8833.22482848258 14522.829703429645 22450.693430156378 21947.708820382373 15878.86418239052 11169.853129558105 18341.69077852648 15443.320534684513 18945.65464582012 0.5126201918591992 0.46624014812976694 0.7665520128455282 1.185004891615585 1.1584560803352648 0.8381269731364913 0.5895733527488559 0.9681212458168139 0.8151378679380548 1.0 14.209579370964335 -5.415521653287646 4.033670366925741 0.9287362138103737 0.49390040497983656 0.5391831857631544 0.16306994225357718 0.19133535644560937 5.345798029695567 0.04849043455629727 0.10700738067856976 3.841301065360383e-06 5.415521653287646 -0.4348358088305372 SEHSHSTT(ph)LPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEHSHSTTLPR 11 0 P16144-4;P16144-2;P16144-3;P16144;J3QRK0 P16144-4 ITGB4 Integrin beta-4 1 SEHSHS(0.115)T(0.203)T(0.682)LPR 77.204 0.041442 3570200.0 8058.2 9696.1 20007.0 15419.0 32323.0 20126.0 14913.0 14450.0 19033.0 12987.0 True False 9422.294103295248 10658.66472870749 20484.042756970022 14555.12341907247 25989.54018259697 19070.55713020189 13500.332679229858 14070.702811040557 19311.321618101596 15341.440294964561 0.6141727192581701 0.6947629768637777 1.335209886629314 0.9487455635993851 1.6940743295873844 1.2430747546213974 0.8799912146228539 0.9171696099263189 1.2587684889299506 1.0 13.905146312772308 -5.1907671400865425 6.4989399791593625 1.1608202861283352 0.6437073021983309 0.4296176056427372 0.23299235537868987 0.23587616028754696 17.666813852504877 0.06207743213232296 0.1678623012687642 6.445147486531497e-06 5.1907671400865425 -0.5171129839300043 SEIDLFNIR ddPTM_PC-9_AZD4547_30min_R2 1 SEIDLFNIR 9 0 D6RBE9;P08758;D6RBL5 D6RBE9 ANXA5 Annexin;Annexin A5 0 98.58200000000001 0.010577 0.0 14453.0 16832.0 13901.0 22282.0 18650.0 17810.0 15895.0 19805.0 18166.0 16836.0 False True 19048.75335892461 22272.614832300016 13716.663657247958 17145.229153468306 16060.769422433154 16696.337884542176 17309.62420730487 16744.592323624824 19126.217673375973 16246.576764479567 1.1724779709022477 1.3709112482695665 0.8442802355285797 1.0553133378197856 0.9885632927637624 1.0276834391996925 1.065432088139914 1.0306535688326715 1.1772460100759357 1.0 13.98784814660282 -5.249245843762501 24.996889002179756 1.0262557695862347 1.2716946136628016 0.551199535423913 0.08950512018885869 538.1386101169214 1103185.5236716159 0.02187616992815405 0.05693190376294452 5.633186842629159e-06 5.249245843762501 0.2454388440765669 SEIDLFNIR ddPTM_PC-9_Lapatinib_30min_R1 4 SEIDLFNIR 9 0 D6RBE9;P08758;D6RBL5 D6RBE9 ANXA5 Annexin;Annexin A5 0 ;;; 150.36 0.0010101 12453100.0 78692.0 86302.0 89486.0 85293.0 91494.0 91157.0 84423.0 95001.0 82584.0 88953.0 False True 77569.83764965464 86102.17302137896 82128.80650594922 91565.73174910707 86112.50280412503 87258.42760734566 88794.00985508855 99415.09327820127 73282.52027192681 104328.40752757779 0.7435159750631688 0.8252994084915849 0.7872142252745457 0.8776682585220418 0.8253984206685258 0.8363822440621466 0.8511009796791642 0.952905307712305 0.7024215360764093 1.0 16.670772516464957 -14.522878745280336 0.1670838771536018 1.6179818952261973 0.7890704112645821 0.3690135659606876 0.06710000711118301 141.56476296284126 1.3216629198557277 29.35590958482998 0.24064458065569178 3.0000000000000132e-15 14.522878745280336 -0.8289114839616152 SEIDLLDIR ddPTM_PC-9_AZD4547_30min_R2 2 SEIDLLDIR 9 0 P12429;D6RA82 P12429 ANXA3 Annexin A3;Annexin 0 ; 140.14 0.0036474000000000003 3507600.0 28403.0 22217.5 39047.0 41866.0 38779.0 38617.0 42480.0 54486.0 37603.0 44483.0 False True 37434.56318089916 29398.872388107502 38529.21126714344 32214.440523252106 33395.20522426461 36202.27288530968 46260.637705335714 46066.440663722395 39590.61781195403 42925.66370957142 0.8720788438863936 0.6848786913818234 0.897579861031999 0.7504704118545531 0.7779776091573457 0.8433713018451807 1.0776918446346742 1.0731678134414182 0.9223064803334945 1.0 15.389552820663397 -7.1407928234803135 4.549580391791513 1.023514759802456 0.7949930938552473 0.7000023541853252 0.06897091749269557 0.12104982718861236 3.9628268557745474 0.026018846129866147 0.019946416786197026 7.231146770939837e-08 7.1407928234803135 -0.2285216659472088 SEIDLLDIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEIDLLDIR 9 0 P12429;D6RA82 P12429 ANXA3 Annexin A3;Annexin 0 95.815 0.024442 850020.0 5977.7 8680.9 8734.5 7712.9 11415.0 6891.6 8537.7 9188.4 8061.8 6270.7 False True 6989.606545043305 9542.68238193055 8942.763605775712 7280.771218559183 9178.312693263133 6530.192364031564 7728.947248404799 8947.21423591454 8179.6885735728165 7407.528271166114 0.9435814875321403 1.2882411018362963 1.207253388500118 0.9828880771065924 1.2390519964655171 0.8815615850499565 1.043390853935693 1.2078542137654298 1.104239939982726 1.0 12.854776511969916 -5.742645275744798 24.989154924520168 1.0728674174820216 1.1605468910903227 0.07233324973007471 0.12777207954764075 636.0369077161785 845685.2993739914 0.03421132947092438 0.059121261933926354 1.8086507976993122e-06 5.742645275744798 0.08767947360830108 SEIDLLDIR ddPTM_PC-9_Lapatinib_30min_R1 1 SEIDLLDIR 9 0 P12429;D6RA82 P12429 ANXA3 Annexin A3;Annexin 0 134.77 0.0050525 2339800.0 22997.0 19359.0 24588.0 22553.0 25554.0 24844.0 22600.0 20714.0 28327.0 23965.0 False True 22669.0585628667 19314.175424913425 22566.46955242474 24211.622854602527 24050.963961096997 23781.48003419262 23770.11741735073 21676.448060174782 25136.51496346591 28107.318318644746 0.8065180144855504 0.6871582413503153 0.8028681105965014 0.8613992477020462 0.8556833379989509 0.8460956596637461 0.845691401359447 0.7712029946946557 0.8943049877081949 1.0 14.778658194244318 -14.522878745276602 0.09161619270799899 1.572622440035009 0.6754656043946888 0.6080361428500703 0.04842699269027802 155.77837844461058 0.9847303410599287 17.4639482670034 1.1619974474613632 3.0000000000258062e-15 14.522878745276602 -0.8971568356403202 SEIDMNDIK ddPTM_PC-9_Lapatinib_30min_R1 2 SEIDMNDIK 9 0 P04083 P04083 ANXA1 Annexin A1 0 ; 142.92 0.0029195999999999996 10243200.0 76568.0 72741.0 81856.0 83430.0 75849.0 77891.0 77418.0 75434.0 77392.0 71720.0 False True 75476.12627914867 72572.57268369375 75126.11565329757 89565.72051432144 71387.71094487156 74559.78350278937 81426.32523081682 78938.939025356 68675.29798611067 84116.70643910716 0.8972786676305082 0.8627605116259478 0.8931176556191254 1.0647792133796734 0.8486745851913469 0.8863849603617548 0.968016089523929 0.938445433339697 0.8164287558717641 1.0 16.360104742493732 SEIPS(ph)PQSQLLEDAEANLVGR ddPTM_PC-9_AZD4547_30min_R2 1 SEIPSPQSQLLEDAEANLVGR 21 0 Q9ULJ8-3;Q9ULJ8;Q9ULJ8-4;Q9ULJ8-5 Q9ULJ8-3 PPP1R9A Neurabin-1 1 S(0.004)EIPS(0.994)PQS(0.001)QLLEDAEANLVGR 168.62 1.5126e-08 12906000.0 16063.0 10277.0 18743.0 25094.0 21890.0 16963.0 15145.0 22528.0 14486.0 19238.0 True False 21170.69986884426 13598.839272311501 18494.455573541352 19308.965998435207 18850.951348904106 15902.300928438455 16492.875660247384 19046.815241939898 15251.700386244866 18564.483475591464 1.1403872290160642 0.7325191293467024 0.9962278561565053 1.0401025174668925 1.0154309638449832 0.856598081457357 0.8884101559804869 1.0259814266840552 0.8215526387414852 1.0 14.18025755482455 -6.74789727327373 24.879085878372248 0.9182511405731137 0.9746029094990125 0.07755771477462625 0.11173390460917239 741.0182275783086 1361370.6574736636 0.03631339100319025 0.03612152056617562 1.7869101952952898e-07 6.74789727327373 0.05635176892589877 SEIPS(ph)PQSQLLEDAEANLVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEIPSPQSQLLEDAEANLVGR 21 0 Q9ULJ8-3;Q9ULJ8;Q9ULJ8-4;Q9ULJ8-5 Q9ULJ8-3 PPP1R9A Neurabin-1 1 S(0.006)EIPS(0.986)PQS(0.008)QLLEDAEANLVGR 153.32 1.976e-05 6604600.0 36650.0 41594.0 38524.0 39906.0 45842.0 36788.0 38430.0 41959.0 34083.0 29788.0 True False 42854.121129504194 45723.17743483042 39442.55826308357 37670.19619699759 36859.58917955047 34858.772518427264 34789.632190894066 40857.62070923534 34581.3993962989 35188.328598321765 1.21785043042789 1.2993847464812833 1.1208988842102805 1.0705309884708247 1.0474947418022127 0.9906345060131609 0.9886696406646972 1.1611128557888926 0.9827519741289499 1.0 15.102809369051093 -5.51147147823464 2.283356153721832 1.0359885843880645 1.2608595572176546 0.7255761298689556 0.05446225447957297 0.1561961689511517 1.601343341548214 0.015464766282746487 0.03780579628496494 3.0798425998022903e-06 5.51147147823464 0.22487097282959012 SEIPS(ph)PQSQLLEDAEANLVGR ddPTM_PC-9_Lapatinib_30min_R1 3 SEIPSPQSQLLEDAEANLVGR 21 0 Q9ULJ8-3;Q9ULJ8;Q9ULJ8-4;Q9ULJ8-5 Q9ULJ8-3 PPP1R9A Neurabin-1 1 S(0.059)EIPS(0.894)PQS(0.047)QLLEDAEANLVGR;S(0.003)EIPS(0.982)PQS(0.015)QLLEDAEANLVGR;S(0.069)EIPS(0.929)PQS(0.003)QLLEDAEANLVGR 171.3 6.3494e-09 20377800.0 247266.9 203076.3 269119.6 214038.8 249310.8 251645.4 200447.6 198972.2 246666.3 191254.0 True False 243740.82866280412 202606.08930432054 246993.6253196976 229779.92736450594 234646.8289078918 240883.1128560785 210825.79593036082 208217.17479572783 218884.1437827081 224311.99907006396 1.0866152041499642 0.9032333987672074 1.1011164197353036 1.024376441372332 1.0460734596484949 1.0738752891272594 0.9398774778183367 0.9282480458421267 0.975802207149603 1.0 17.77514727067848 -7.271872998373673 24.770778343575046 0.9550025984683954 1.0354850166478606 0.328797525715119 0.05433559055430313 745.8433779256552 1770722.5902875098 0.021898802127585243 0.014938920135090536 5.347207060085508e-08 7.271872998373673 0.08048241817946522 SEIS(ph)PEGEK ddPTM_PC-9_AZD4547_30min_R2 2 SEISPEGEK 9 0 Q96PY6-4;Q96PY6-2;Q96PY6-6;Q96PY6;Q96PY6-3 Q96PY6-4 NEK1 Serine/threonine-protein kinase Nek1 1 S(0.002)EIS(0.998)PEGEK;S(0.001)EIS(0.999)PEGEK 115.57 0.0019706 18042900.0 98394.0 121544.0 99346.0 100400.0 98332.0 113877.0 106898.0 120165.0 121134.0 112788.0 True False 129681.24527766088 160830.72107753545 98028.60712847684 77254.3311645372 84680.29913387097 106756.25318798462 116411.71491113432 101596.26036699729 127536.89594003774 108839.3264499952 1.1914925377385648 1.4776894191037373 0.9006726734340348 0.7098016285504182 0.7780303489178263 0.9808610239519663 1.0695740106827851 0.9334517557279661 1.1717905659645265 1.0 16.73184040807513 -5.271349086689238 24.939789898601877 0.9322951577608805 1.3345909800170621 0.5519390942776015 0.14085553050645958 436.1990808350131 1097785.0544038522 0.03917767231077058 0.0831511709735224 5.3536615623398595e-06 5.271349086689238 0.40229582225618166 SEIS(ph)PEGEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SEISPEGEK 9 0 Q96PY6-4;Q96PY6-2;Q96PY6-6;Q96PY6;Q96PY6-3 Q96PY6-4 NEK1 Serine/threonine-protein kinase Nek1 1 S(0.011)EIS(0.989)PEGEK;SEIS(1)PEGEK;SEIS(1)PEGEK 103.31 0.0028964000000000004 11395000.0 133264.0 171262.0 132015.0 154436.0 170887.0 133161.0 167301.0 117630.0 120318.0 126979.0 True False 155822.96311602302 188263.7595288728 135162.73826967546 145783.45160826712 137402.91907259382 126177.80274345676 151453.03812565136 114542.33713928702 122077.42313070732 149999.2875347893 1.0388246882831562 1.2550976916154273 0.9010892017625564 0.9718942936609322 0.9160238113846108 0.8411893470773478 1.0096917166391532 0.7636192079427127 0.8138533531527203 1.0 17.194596122674852 -5.278518409784706 24.39071737090283 0.8983750214264661 1.1469611720631787 0.5435894663790866 0.08966784766078084 366.26491532031326 523066.2068335387 0.02309911021888794 0.048293775615404884 5.266008917584957e-06 5.278518409784706 0.24858615063671263 SEIS(ph)PEGEK ddPTM_PC-9_Lapatinib_30min_R1 1 SEISPEGEK 9 0 Q96PY6-4;Q96PY6-2;Q96PY6-6;Q96PY6;Q96PY6-3 Q96PY6-4 NEK1 Serine/threonine-protein kinase Nek1 1 SEIS(1)PEGEK 96.229 0.005171800000000001 8303200.0 37172.0 56199.0 45301.0 46598.0 51593.0 49002.0 50496.0 46579.0 43108.0 44273.0 True False 36641.92046349008 56068.87466835624 41576.52664691696 50024.972366371134 48558.40117574069 46906.29868924119 53110.43580117441 48743.23038499957 38252.72309263563 51925.5290599357 0.7056629200868744 1.0797939988948024 0.8006952918847822 0.9633984144606245 0.9351546735266104 0.9033379060057143 1.022819348453263 0.9387141790839931 0.7366843205098967 1.0 15.664156390056197 -4.7324272757747465 24.844059210362595 0.9283098067126109 0.7056615276553365 0.3317833797087558 0.09593472452764258 3828.801303262412 3278541.763692476 0.022573693218462035 2.4965785882206255 1.8517089437904506e-05 4.7324272757747465 -0.22264827905727436 SELCS(ph)SPLGK ddPTM_PC-9_AZD4547_30min_R2 3 SELCSSPLGK 10 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 SELCS(0.653)S(0.347)PLGK;SELCS(0.89)S(0.11)PLGK;SELCS(0.879)S(0.121)PLGK 202.31 0.00017587 233380600.0 1039164.0 1037735.0 1274595.0 1269304.0 1207601.0 1247398.0 1279726.0 1498710.0 1160933.0 1190727.0 True False 1369596.5360460496 1373162.544736029 1257693.03749442 976685.5733513115 1039946.4458605739 1169398.0058676118 1393619.1348422393 1267118.8064296758 1222297.548288307 1149040.0101590918 1.1919485169680213 1.1950519847832854 1.0945598294007923 0.8500013617594423 0.9050567749303933 1.0177173949806164 1.2128551856512673 1.1027629980040776 1.0637554284285298 1.0 20.13199760355984 -5.433072274545658 4.583726963669042 1.0254160386176125 1.1893495545698967 0.3406326755841842 0.0944984948548525 0.2924310113349514 10.475397425310687 0.029113908567477042 0.0625267386993047 3.689161990577609e-06 5.433072274545658 0.16393351595228411 SELCS(ph)SPLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SELCSSPLGK 10 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 SELCS(0.58)S(0.42)PLGK;SELCS(0.5)S(0.5)PLGK 96.015 0.0056941000000000005 27070400.0 67552.0 71757.0 74129.0 86782.0 85898.0 73305.0 84819.0 80761.0 77362.0 64276.0 True False 78987.21938718313 78880.56073450804 75896.51649579788 81919.88589104012 69066.90352395251 69460.7567539228 76784.33028361798 78641.10932335256 78493.27289547486 75928.72999146397 1.0402810556170634 1.0388763349969887 0.9995757403598123 1.0789049928827952 0.9096280621540374 0.9148152058085482 1.011268465734251 1.0357227011724484 1.0337756591516702 1.0 16.212358256936376 -6.237045841323301 24.969584634767834 0.9838718144264538 1.036526167254429 0.27034439236319796 0.04432999021655004 1270.7742290654078 1300782.5165459376 0.014566305679234726 0.018796937372599562 5.793675389001017e-07 6.237045841323301 0.05265435282797526 SELCS(ph)SPLGK ddPTM_PC-9_Lapatinib_30min_R1 1 SELCSSPLGK 10 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 SELCS(0.749)S(0.251)PLGK 157.38 0.00037561 13319000.0 39434.0 77580.0 75001.0 71810.0 88865.0 90100.0 68921.0 82186.0 80579.0 67640.0 True False 38871.663928690075 77400.36827650109 68834.70729223243 77091.14695113746 83638.13541531206 86246.63303335839 72489.39214695696 86004.66159474407 71503.34448551277 79331.48387536533 0.4899903799828056 0.9756576392558326 0.8676846055265526 0.9717598005887854 1.0542867891732965 1.0871677777874065 0.9137531356509389 1.0841176465306348 0.901323673686086 1.0 16.27560591403534 -4.528008352356469 2.13206190680835 0.9924752017310092 3.1980250017955407e-13 0.7965309370115501 0.07425617239485065 0.8027596773559412 2.1015495437985385 0.01946138848955687 1.9802051376179866 2.9647743704012696e-05 4.528008352356469 -0.9924752017306894 down SELCSS(ph)PLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SELCSSPLGK 10 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 SELCS(0.357)S(0.643)PLGK;SELCS(0.398)S(0.602)PLGK;SELCS(0.041)S(0.959)PLGK;SELCS(0.216)S(0.783)PLGK 206.36 5.908e-05 136967500.0 781138.0 760861.0 858063.0 879168.0 1016033.0 745008.0 1016511.0 798643.0 786822.0 707435.0 True False 913369.2352212446 836394.2517248271 878522.4761420486 829911.0672611138 816948.6273039196 705938.4689683713 920219.7191776719 777679.4674822057 798327.7832290201 835687.3654476216 1.0929556590005571 1.0008458740749622 1.0512573391264366 0.9930879675518203 0.9775768559888842 0.8447399089134816 1.1011530833480676 0.9305866040772977 0.9552947863480137 1.0 19.672603798710426 -5.931746100468244 2.6646218268008175 0.965674385975791 1.0446081805542629 0.2404851131155431 0.06326532623778716 0.4137466544278843 5.955698891451128 0.018800254727391767 0.02973962121595138 1.1701833098238574e-06 5.931746100468244 0.07893379457847183 SELCSS(ph)PLGK ddPTM_PC-9_Lapatinib_30min_R1 2 SELCSSPLGK 10 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 SELCS(0.089)S(0.911)PLGK;SELCS(0.383)S(0.617)PLGK 199.8 0.00049071 213860000.0 319430.0 650820.0 672320.0 667180.0 683140.0 683600.0 684790.0 665080.0 698920.0 536550.0 True False 314874.86962371226 649313.0662762631 617044.4448302514 716246.6428472339 642959.0483049151 654364.0215494316 720245.0754967971 695982.0447939087 620200.2696461191 629291.952592065 0.5003637315346827 1.0318153022642842 0.9805376380368986 1.1381786147065778 1.0217182114860281 1.0398417123468595 1.1445324742038963 1.105976394465472 0.985552519925772 1.0 19.2633699682291 -4.758777821695633 5.175493168746372 1.0575129589099226 0.46668113976017206 0.8933185351632345 0.056971224155083815 0.04964890020210355 3.716960903311967 0.014258052841772952 0.10652864754890619 1.7426981826763177e-05 4.758777821695633 -0.5908318191497506 SELDTEKVPLS(ph)PLPGPK ddPTM_PC-9_AZD4547_30min_R2 1 SELDTEKVPLSPLPGPK 17 1 Q8NHU6-2;Q8NHU6 Q8NHU6-2 TDRD7 Tudor domain-containing protein 7 1 SELDTEKVPLS(1)PLPGPK 92.575 0.00095443 2928000.0 45945.0 51629.0 57768.0 78701.0 60037.0 56119.0 64642.0 87673.0 71958.0 69150.0 True False 60554.554284632315 68317.06458987744 57001.95857505931 60557.700368329104 51701.898864054674 52609.87005854142 70395.01277185288 74125.15237511545 75761.5529748315 66729.07954762195 0.9074687481852178 1.023797496579017 0.8542296546197559 0.907515895301859 0.7748031175397383 0.7884099468357839 1.0549375661867881 1.1108373272587284 1.1353603779408261 1.0 16.026027983186985 -7.387997787316255 5.69397212139077 1.0901696951696982 0.8791325428577497 0.6420815819385042 0.07289167160437578 0.15751196464002631 6.643297452979945 0.03373903848463407 0.022436314785510895 4.0926274487443195e-08 7.387997787316255 -0.21103715231194853 SELDTEKVPLS(ph)PLPGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SELDTEKVPLSPLPGPK 17 1 Q8NHU6-2;Q8NHU6 Q8NHU6-2 TDRD7 Tudor domain-containing protein 7 1 SELDTEKVPLS(1)PLPGPK;S(0.001)ELDT(0.002)EKVPLS(0.997)PLPGPK 98.76 0.00062482 12711300.0 64171.0 53688.0 61647.0 69567.0 99478.0 93587.0 102501.0 119384.0 83814.0 82557.0 True False 75033.8828649771 59017.789828368856 63116.89827754942 65669.38652925692 79986.00000879806 88679.13296950242 92791.36323702423 116250.29649780368 85039.62118949044 97523.93057914774 0.7693894454354633 0.6051621328005401 0.6471939543733369 0.6733668971223576 0.8201679273363949 0.9093063870875556 0.9514727583884379 1.1920181621828514 0.8719872208234535 1.0 16.57346865268527 -6.697988925453605 1.4029997591346994 1.0213472496280294 0.6616784658844834 0.7527238615181525 0.08512997928882986 0.18644734050887868 0.766356873023825 0.03710757148170707 0.035454390906812544 2.004523142224837e-07 6.697988925453605 -0.35966878374354594 SELDTEKVPLS(ph)PLPGPK ddPTM_PC-9_Lapatinib_30min_R1 1 SELDTEKVPLSPLPGPK 17 1 Q8NHU6-2;Q8NHU6 Q8NHU6-2 TDRD7 Tudor domain-containing protein 7 1 SELDT(0.014)EKVPLS(0.985)PLPGPK 62.19 0.013993 3554700.0 34790.0 25781.0 28248.0 20344.0 26034.0 31519.0 35653.0 32573.0 35795.0 41019.0 True False 34293.88822029536 25721.305678479916 25925.558480433323 21840.165625594545 24502.731304813315 30171.005844377603 37498.93788853119 34086.46049358275 31763.39016193958 48109.07949561814 0.7128360920607285 0.534645558554548 0.5388911771382919 0.453971804378086 0.509316153243902 0.6271374584734183 0.7794565658223965 0.7085244791825087 0.6602369135920101 1.0 15.554021575148932 -7.0857529263625825 3.234883860626242 0.7629766179394775 0.5437816549278476 0.5303321447938001 0.10417548351504732 0.22204634563198714 4.458336944364258 0.04180196509546105 0.032184433983128306 8.208183817284168e-08 7.0857529263625825 -0.21919496301162988 SELGNQS(ph)PSTSSR ddPTM_PC-9_AZD4547_30min_R2 1 SELGNQSPSTSSR 13 0 H0YD16;A0A0A0MSK5;J3KN66;Q5JTV8;Q5JTV8-3 H0YD16 TOR1AIP1 Torsin-1A-interacting protein 1 1 S(0.43)ELGNQS(0.568)PS(0.001)TSSR 95.755 0.0034357 11019000.0 19317.0 18170.0 24239.0 24641.0 20730.0 14607.0 23332.0 20307.0 17377.0 14891.0 True False 25459.404181439626 24043.09716628394 23917.575022518737 18960.398149654993 17851.997325846605 13693.62198088195 25408.50279992686 17169.019758437218 18295.512744151387 14369.670622467645 1.7717458423599959 1.673183596059011 1.6644483823534897 1.3194733997597365 1.2423386586143583 0.9529530871411441 1.7682035634275075 1.1948095547571327 1.2732033478586144 1.0 13.810739372675348 -1.5228787481260397 0.298546256146986 1.173266130838205 6.863046002461955 0.4680927534069971 0.2145928540042853 51.4176400431838 0.7323891754950033 0.22630631068155055 155.97951060147332 0.02999999980342586 1.5228787481260397 5.68977987162375 SELGNQS(ph)PSTSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SELGNQSPSTSSR 13 0 H0YD16;A0A0A0MSK5;J3KN66;Q5JTV8;Q5JTV8-3 H0YD16 TOR1AIP1 Torsin-1A-interacting protein 1 1 SELGNQS(0.956)PS(0.037)T(0.004)S(0.002)S(0.001)R;SELGNQS(1)PSTSSR;SELGNQS(0.995)PS(0.004)T(0.001)SSR 158.89 0.00025629 23203300.0 66598.0 61708.0 62062.0 52712.0 84137.0 49986.0 58141.0 45310.0 47313.0 38271.0 True False 77871.726029542 67833.96242603536 63541.793451445716 49758.71753460974 67650.9588325081 47364.646164676116 52633.4635756121 44120.66050991333 48004.8631175979 45209.22934693072 1.72247408669506 1.5004450066044015 1.4055049017498815 1.1006318456076025 1.4963970810774496 1.0476764777653023 1.164219437843291 0.9759215352099053 1.0618376780814773 1.0 15.464329704708279 -1.5228787545485258 0.26466146169068605 0.9736571897406491 6.150453797129983 0.7634752463527577 0.12055043660377804 23.419846138537437 0.3250831083108073 0.13982088039088877 55.0069536528652 0.029999999359776243 1.5228787545485258 5.176796607389334 SELGNQS(ph)PSTSSR ddPTM_PC-9_Lapatinib_30min_R1 2 SELGNQSPSTSSR 13 0 H0YD16;A0A0A0MSK5;J3KN66;Q5JTV8;Q5JTV8-3 H0YD16 TOR1AIP1 Torsin-1A-interacting protein 1 1 S(0.002)ELGNQS(0.998)PSTSSR;SELGNQS(0.999)PS(0.001)TSSR 142.95 8.377700000000001e-05 19545400.0 63948.0 64721.0 44004.0 29845.0 30947.0 44703.0 35187.0 26767.0 49952.0 15513.8 True False 63036.089793373074 64571.142500946364 40386.16098035217 32039.900860001406 29126.758304142943 42791.15689778272 37008.81068868671 28010.69253773769 44325.879742120575 18195.33965916089 3.464408522961318 3.54877368109127 2.2195881877928434 1.7608850101278615 1.6007812357313351 2.3517646660824196 2.033971961059475 1.53944323450071 2.4361116952166166 1.0 14.151281362304365 -5.337831902315295 3.399654288935265 1.8677676441232232 3.5374363773425213 0.73934837856792 0.39390025607649426 0.11184158491692373 2.484406015754366 0.10072585608828034 0.2485255604324885 4.593757840646833e-06 5.337831902315295 1.669668733219298 SELISS(ph)TFK ddPTM_PC-9_Lapatinib_30min_R1 1 SELISSTFK 9 0 H0YHG7;Q92730 H0YHG7 RND1 Rho-related GTP-binding protein Rho6 1 SELIS(0.072)S(0.464)T(0.464)FK 75.109 0.026451 2659800.0 3911.1 7870.9 14516.0 21642.0 22530.0 55636.0 8988.3 15246.0 37103.0 4507.8 True False 3855.3269967920996 7852.675414636657 13322.550513380422 23233.624875595604 21204.829695684253 53256.57797385046 9453.670193910331 15954.38481825937 32924.06942808897 5286.967223734064 0.729213334155904 1.4852892182468445 2.5198852101017963 4.394508967503344 4.010773813859162 10.073181035579895 1.7881083414838008 3.0176818094573234 6.227401842078275 1.0 12.368224667499176 -5.540724143195332 1.9197672531076393 4.5988381406119325 0.9681673064610323 0.2340945746109192 2.37764395677486 0.5008043744131581 3.6167750354066053 0.7078803485420662 1.8476516711059003 2.879226672075906e-06 5.540724143195332 -3.6306708341509 SELISST(ph)FK ddPTM_PC-9_Lapatinib_30min_R1 1 SELISSTFK 9 0 H0YHG7;Q92730 H0YHG7 RND1 Rho-related GTP-binding protein Rho6 1 SELIS(0.01)S(0.339)T(0.651)FK 91.65799999999999 0.018658 2593400.0 5819.3 10843.0 20277.0 23821.0 22887.0 70261.0 5132.8 12615.0 41416.0 6393.3 True False 5736.315714871077 10817.893699691933 18609.903331483514 25572.87580452652 21540.83165757327 67256.10081639062 5398.551269016716 13201.138953321664 36751.293950185485 7498.373386463234 0.7650080116344715 1.4426987217282894 2.4818587141952486 3.410456439885092 2.872733931396481 8.969425414024812 0.7199629827400549 1.7605336881667693 4.901235515496249 1.0 12.872361952030767 -5.35768444327189 1.6984984474733047 3.5259089582472094 0.7981166701981588 0.14241388270897148 2.2220829596351814 0.8473242456096223 4.37290738956298 0.666716476776328 2.5665549915964037 4.388494483089699e-06 5.35768444327189 -2.7277922880490504 SELS(ph)PVAR ddPTM_PC-9_Lapatinib_30min_R1 1 SELSPVAR 8 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 S(0.023)ELS(0.977)PVAR 81.525 0.017759999999999998 15162000.0 52695.0 50982.0 47471.0 47601.0 48377.0 45527.0 32819.0 32040.0 48326.0 34961.0 True False 51943.5596369205 50863.95431132472 43568.11762335918 51101.736332281034 45531.55997284143 43579.91633862053 34518.207235399685 33528.69536777059 42883.01698465967 41003.96226739571 1.2667936649191438 1.2404643721899329 1.0625343311761448 1.2462633732573343 1.1104185414063226 1.0628220769111645 0.8418261389057717 0.8176940352525619 1.0458261741880024 1.0 15.323475705556381 -6.886411070726112 2.1651743736750126 0.9131959319953282 1.1926104670744224 0.6693807492625972 0.0856334664863017 0.18080338160194634 1.7297270331188557 0.035330983944062096 0.029949152910869983 1.2989395168333167e-07 6.886411070726112 0.2794145350790942 SELSQDAEPAGS(ph)QETK ddPTM_PC-9_AZD4547_30min_R2 2 SELSQDAEPAGSQETK 16 0 Q9BVJ6-3;Q9BVJ6;Q9BVJ6-2;X6RJY0 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 1 SELSQDAEPAGS(0.994)QET(0.006)K;SELSQDAEPAGS(1)QETK 154.48 2.932e-05 37209000.0 269189.0 273524.0 276003.0 307586.0 287555.0 306128.0 303391.0 322239.0 320011.0 295543.0 True False 354785.5025209677 361935.2839466509 272343.01988284313 236676.7998563279 247632.95181060428 286985.76776637405 330392.2112537553 272444.3668655665 336926.1281445953 285196.12952628866 1.2440053205149282 1.2690750205755812 0.9549323840236031 0.8298738143797693 0.868290015793423 1.006275114052417 1.1584736854687945 0.9552877429230795 1.1813839434084548 1.0 18.121594877147366 -5.258677770479377 24.900081943868408 0.9886339422927412 1.2565402005605284 0.5024570691714059 0.10425351530339162 188.90451930868835 1703237.353365143 0.02902597439149801 0.06994977805498061 5.512165258234024e-06 5.258677770479377 0.26790625826778725 SELSQDAEPAGS(ph)QETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SELSQDAEPAGSQETK 16 0 Q9BVJ6-3;Q9BVJ6;Q9BVJ6-2;X6RJY0 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 1 SELSQDAEPAGS(0.608)QET(0.392)K;SELSQDAEPAGS(1)QETK 202.81 2.0628e-13 18109500.0 122295.0 136687.0 111105.0 122042.0 143827.0 92477.0 125590.0 120731.0 112971.0 98772.0 True False 142997.12806364815 150256.38202708715 113754.16456805915 115204.38240550269 115645.13182075841 87627.34332354563 113693.20600714008 117561.93917506849 114622.98715486546 116678.581721278 1.225564503391376 1.2877803261786287 0.9749361270073997 0.9873652962349433 0.9911427625766973 0.7510148137802188 0.9744136784138379 1.0075708621133281 0.9823824172689813 1.0 16.832180229308726 -5.285237946980223 6.982658136871463 0.9536597841024077 1.2571695663843918 0.7309482162686796 0.07229532179876462 0.08455573132806242 18.183883407480163 0.019928524045418467 0.04375660637578035 5.185158697855272e-06 5.285237946980223 0.3035097822819841 SELSQDAEPAGS(ph)QETK ddPTM_PC-9_Lapatinib_30min_R1 2 SELSQDAEPAGSQETK 16 0 Q9BVJ6-3;Q9BVJ6;Q9BVJ6-2;X6RJY0 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 1 SELSQDAEPAGS(0.999)QET(0.001)K;SELS(0.008)QDAEPAGS(0.992)QETK 189.84 2.8178e-08 39137000.0 199481.0 268618.0 250415.0 257613.0 280042.0 277213.0 263902.0 271424.0 290046.0 255707.0 True False 196636.36435966505 267996.03152484115 229826.84532985406 276558.7193917762 263570.4801437558 265357.24620506563 277565.5542775968 284035.34992202726 257377.96516021583 299905.6142418394 0.6556608313477601 0.8936012491874633 0.7663305867442852 0.9221525248565817 0.8788447685784785 0.8848025298755678 0.9255096973735614 0.9470824700633494 0.8581965556425699 1.0 18.19414900418947 -3.5423313998355774 0.5353418469618629 0.9224712022716857 1.8427311645047255e-30 0.6071953991007796 0.05819644992775306 9.825953041321721 0.7710236060580266 0.02875336639864451 7.584058361580531 0.00028685907929334846 3.5423313998355774 -0.9224712022716857 SEMEVQDAELK ddPTM_PC-9_Lapatinib_30min_R1 2 SEMEVQDAELK 11 0 Q9UQ80;Q9UQ80-2 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 0 ; 144.65 0.00084119 4827600.0 36162.0 41612.0 41347.0 38974.0 45444.0 38438.0 44794.0 42077.0 34950.0 44399.0 False True 35646.3232487014 41515.64997063363 37947.60926403556 41840.2779734527 42771.07326634157 36794.09634335437 47113.21414127472 44032.05102964056 31013.562960184066 52073.3079920512 0.6845411713452635 0.7972539400986556 0.7287343694360289 0.803487997725043 0.8213627079898672 0.7065826574522759 0.9047478633096706 0.8455781421906573 0.5955750490235453 1.0 15.668256437365352 -11.96182082271641 2.4162116336385973 3.613790606366712 0.7726864546752119 0.40496530112144224 0.08492033471561218 2737565.8716592253 938338.2615056172 38633490.57167866 0.021241684796072167 1.091890725919133e-12 11.96182082271641 -2.8411041516915 SEMIEKPLFDFSLITTGIQEPQT(ph)DETRNSPTQK ddPTM_PC-9_AZD4547_30min_R2 1 SEMIEKPLFDFSLITTGIQEPQTDETRNSPTQK 33 2 H3BSS6;Q9H2Y7;H3BNX5 H3BSS6 ZNF106 Zinc finger protein 106 1 SEMIEKPLFDFSLITTGIQEPQT(0.33)DET(0.33)RNS(0.33)PT(0.009)QK 92.198 2.068e-12 2510000.0 6584.8 6113.6 7381.9 9221.6 9152.1 8838.0 10026.0 7005.0 7733.2 8660.7 True False 8678.629427651475 8089.701642035967 7284.011182752225 7095.702592299758 7881.48889174533 8285.35846286265 10918.294577064398 5922.538208886235 8141.961164359296 8357.491529111921 1.0384251539377483 0.9679581024828857 0.871554719185726 0.8490230073919988 0.9430447957131017 0.9913690530229068 1.3064080937482674 0.7086502197765999 0.9742111177735734 1.0 13.028854272235616 -6.7197909408264085 5.140741352494205 0.9974427818953594 0.9267552198192809 0.04502783773670482 0.1424019412308364 0.7154610332909628 43.64227542953606 0.04999034628803856 0.048694739656835864 1.9063781828497308e-07 6.7197909408264085 -0.07068756207607851 SENFEELLK ddPTM_PC-9_AZD4547_30min_R2 2 SENFEELLK 9 0 P29373;Q5SYZ4 P29373 CRABP2 Cellular retinoic acid-binding protein 2 0 ; 105.2 0.008329999999999999 2476600.0 20346.2 16571.5 23121.0 31799.0 26988.0 24212.0 24462.0 28158.0 21300.9 30942.0 False True 26815.868372749745 21927.913301655168 22814.40043300697 24468.231839652566 23241.18204678959 22698.019812494957 26639.070610826773 23806.828106469457 22426.82208735078 29858.729998011822 0.8980913915138156 0.7343886797300241 0.7640780580596057 0.8194665962444421 0.7783714192913472 0.760180349733774 0.892170250127871 0.7973154956039544 0.7510976551529184 1.0 14.86586518318214 -11.471661573965097 2.441707077666663 1.1514378408038353 0.7979838380675248 0.5588062725012775 0.053442091478981706 14930922.278490497 6975602.419619777 12838507.358775102 0.013623357525623731 3.3755024382734475e-12 11.471661573965097 -0.35345400273631045 SENFEELLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SENFEELLK 9 0 P29373;Q5SYZ4 P29373 CRABP2 Cellular retinoic acid-binding protein 2 0 ; 110.53 0.0090559 1888100.0 18825.9 21225.0 20742.4 26066.0 25524.0 23355.0 26966.0 25690.0 18384.199999999997 20553.2 False True 22012.75304152614 23332.077728861757 21236.977481990052 24605.606527112202 20522.755425567088 22130.222685872257 24411.585263066616 25015.66472080497 18653.034145510617 24279.332460958318 0.9066457274689538 0.9609851410198461 0.8746936315543091 1.0134383458309053 0.8452767578584837 0.9114839842264248 1.0054471350199172 1.030327533140818 0.7682679981216572 1.0 14.567441136048147 SENFEELLK ddPTM_PC-9_Lapatinib_30min_R1 2 SENFEELLK 9 0 P29373;Q5SYZ4 P29373 CRABP2 Cellular retinoic acid-binding protein 2 0 ; 134.68 1.9625e-06 0.0 24822.0 21281.0 21366.0 19877.5 19082.6 22992.0 18173.9 15879.400000000001 22564.0 17873.800000000003 False True 24468.0337282027 21231.725152000738 19609.36995514509 21339.357659396148 17960.198985835093 22008.685756969764 19114.855616424342 16617.214894599758 20022.604710546308 20963.262514658563 1.1671863437808607 1.0128063385722739 0.935415942124144 1.0179406781017315 0.8567463663290207 1.0498693007150097 0.9118263725914932 0.7926826696455368 0.9551282724502209 1.0 14.355575640672846 -1.5228787960199222 0.7567670140107718 0.9252035394596365 45.458817207261355 0.4793352200028578 0.07192635721558796 331.0830667970115 1.3895196522164588 0.026635733034163316 25156.70487774635 0.029999996495033873 1.5228787960199222 44.53361366780172 SENSSTQS(ph)SPEMPTTK ddPTM_PC-9_AZD4547_30min_R2 1 SENSSTQSSPEMPTTK 16 0 J3KPC5;P47736-3;F2Z357;P47736;A0A0A0MQY8;X6R8W7;P47736-2;P47736-4 J3KPC5;P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 SENSSTQS(0.5)S(0.5)PEMPTTK 137.73 9.3389e-07 0.0 5541.3 7238.4 9530.4 14336.0 11326.0 10490.0 7484.4 12540.0 6951.2 11534.0 True False 7303.318133799833 9578.071245373125 9404.020668947256 11031.056688992077 9753.580400990768 9834.058641709566 8150.497100796014 10602.231140532956 7318.626240843943 11130.198170676367 0.6561714375437774 0.8605481320725737 0.844910443169206 0.9910925681498207 0.8763168679860133 0.8835474886348733 0.7322867909278851 0.9525644537458108 0.657546804523715 1.0 13.442191659318885 -12.059214364395727 2.2550638633029503 3.6177574667008265 0.8384182907739077 0.17889311252326612 0.10841398533410884 5011298.428258364 624690.4587538036 66918657.36813172 0.02609145160436162 8.725405828006297e-13 12.059214364395727 -2.7793391759269186 SENSSTQS(ph)SPEMPTTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SENSSTQSSPEMPTTK 16 0 J3KPC5;P47736-3;F2Z357;P47736;A0A0A0MQY8;X6R8W7;P47736-2;P47736-4 J3KPC5;P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 SENSSTQS(0.5)S(0.5)PEMPTTK 139.0 7.7798e-07 0.0 7676.7 6934.1 7809.0 11775.0 13249.0 11718.0 10973.0 11074.0 10643.0 8897.9 True False 8976.21368826371 7622.471622129579 7995.196175797419 11115.284925065069 10652.953558742302 11103.48745163996 9933.558002359632 10783.319233872877 10798.633740422174 10511.018834262355 0.8539813152084076 0.7251886560494886 0.760649020029894 1.0574888220001102 1.0135034221437496 1.0563664309539964 0.9450613835815423 1.0259061851095648 1.0273631805531822 1.0 13.359614896223308 -5.757669121876259 24.999824662765906 1.0174127474004233 0.7744645022381 0.8698304630091511 0.04217791301885391 29.802620595889636 197611.5302644966 0.011352606708538536 0.018738937915274978 1.7471527580479799e-06 5.757669121876259 -0.24294824516232327 SEPAVVS(ph)LEYGVAR ddPTM_PC-9_AZD4547_30min_R2 2 SEPAVVSLEYGVAR 14 0 Q9Y217 Q9Y217 MTMR6 Myotubularin-related protein 6 1 SEPAVVS(0.998)LEY(0.002)GVAR;SEPAVVS(1)LEYGVAR 100.11 0.0091095 1690800.0 16110.7 12728.9 16767.4 24928.3 21630.9 19258.2 17635.5 21490.7 12603.6 18142.0 True False 21233.567476622633 16843.2679977937 16545.053320375475 19181.46557339574 18627.822911512565 18053.981709606396 19205.02533550959 18169.806122157217 13269.800565240626 17506.854101995028 1.2128716760256155 0.9620956397799816 0.9450614727228492 1.0956546197074823 1.0640302822532688 1.0312521943933388 1.097000364749772 1.0378681410320683 0.7579774463150658 1.0 14.095632241207483 -8.137592113002682 8.106283853392336 0.8800099026749519 1.0519291634542265 0.387008381578844 0.08901413211555777 0.27376223216144413 16.55442310747578 0.057920240777863015 0.021746462349062284 7.284636524235826e-09 8.137592113002682 0.17191926077927455 SEPAVVS(ph)LEYGVAR ddPTM_PC-9_Lapatinib_30min_R1 1 SEPAVVSLEYGVAR 14 0 Q9Y217 Q9Y217 MTMR6 Myotubularin-related protein 6 1 SEPAVVS(0.999)LEY(0.001)GVAR 106.55 0.0032448999999999998 0.0 11417.0 11195.0 12907.0 9138.5 7953.5 10346.0 12695.0 10234.0 9947.4 8273.0 True False 11254.191486378626 11169.07866531875 11845.836282460807 9810.575775142337 7485.690767182631 9903.525697703948 13352.284982887933 10709.509001053808 8827.019061234194 9702.977026920424 1.1598699507537156 1.1510981252795611 1.2208455456088505 1.0110892510539173 0.7714839215236682 1.0206687772450778 1.3761018856215663 1.1037343457931326 0.9097227620702463 1.0 13.244211741552492 -5.766986731068517 24.775155992621322 1.0354329781113814 1.1746539052338816 0.18085608364487582 0.14531543949231718 246.1910525386317 1099527.3014216218 0.04527792734965854 0.06939166718957042 1.7100675617192986e-06 5.766986731068517 0.13922092712250023 SEPAVVSLEY(ph)GVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEPAVVSLEYGVAR 14 0 Q9Y217 Q9Y217 MTMR6 Myotubularin-related protein 6 1 S(0.03)EPAVVS(0.464)LEY(0.506)GVAR 76.282 0.023906 1245000.0 5776.8 4497.1 4623.0 4837.0 6874.6 5551.4 4223.0 5693.0 4118.6 4999.9 True False 6754.698142999178 4943.542367701496 4733.229852825135 4565.998571765584 5527.571479729021 5260.274811318831 3822.966868127654 5543.564782232105 4178.82673337431 5906.342290813379 1.1436347252520933 0.8369888036104164 0.8013808918909284 0.7730670433488858 0.9358704943881273 0.8906146227760233 0.6472646995203494 0.9385783128171337 0.7075151638051833 1.0 12.528049252198887 -4.761604579532961 7.0920038821554225 0.8302385224606162 1.1499847580221167 0.43862063591057643 0.10392393619881848 0.09489391298176435 28.727196097534833 0.02421691519865511 0.1461733149582646 1.7313920556727063e-05 4.761604579532961 0.3197462355615005 SEPHS(ph)PGIPEIFR ddPTM_PC-9_AZD4547_30min_R2 4 SEPHSPGIPEIFR 13 0 Q8ND82;Q9UJJ2 Q8ND82 ZNF280C Zinc finger protein 280C 1 SEPHS(1)PGIPEIFR;SEPHS(1)PGIPEIFR;SEPHS(1)PGIPEIFR;SEPHS(1)PGIPEIFR 160.8 3.5918000000000004e-05 30208500.0 75864.0 82307.0 121806.0 159053.0 124042.0 122739.0 86462.0 122407.0 86401.0 96817.0 True False 99987.17393077258 108911.12814889003 120190.77285337332 122385.78819435403 106820.90942077474 115064.11092705339 94156.95050091199 103491.81078303164 90967.98046886257 93427.4662988013 1.070211768464232 1.165729227854351 1.2864607980374547 1.3099551239347296 1.143356591509592 1.2315876207008911 1.0078080272430554 1.10772361579455 0.9736749167308812 1.0 16.511559122930272 -7.26190246293158 24.99994841836242 1.0312786015615323 1.2057911455170813 0.5921810147397528 0.07252532806888232 32.856822610384775 1773732.8253530208 0.03045362878462643 0.02197547635421857 5.471388295833426e-08 7.26190246293158 0.17451254395554905 SEPHS(ph)PGIPEIFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SEPHSPGIPEIFR 13 0 Q8ND82;Q9UJJ2 Q8ND82 ZNF280C Zinc finger protein 280C 1 SEPHS(1)PGIPEIFR;SEPHS(1)PGIPEIFR;SEPHS(1)PGIPEIFR;S(0.002)EPHS(0.998)PGIPEIFR;S(0.004)EPHS(0.996)PGIPEIFR;S(0.002)EPHS(0.998)PGIPEIFR 134.88 2.7496999999999998e-05 18674500.0 64574.399999999994 77643.8 95868.4 117646.0 122949.4 113761.0 120984.2 117967.6 121541.6 94729.0 True False 75505.57051746402 85351.76333400235 98154.26623893174 111054.67603347798 98858.34766965255 107795.17289520502 109523.70072624431 114871.0754970038 123318.9159658831 111902.61782564872 0.6747435581454083 0.7627324989571356 0.8771400360969412 0.9924225026308868 0.8834319481576386 0.9632944696893208 0.9787411845618222 1.026527151277016 1.1020199380681308 1.0 16.77188426124178 -3.8523146670845567 0.41823583453165486 1.033348807673161 1.6814600626389017e-17 0.8611100302952656 0.04551184921722123 4.209602450196406 0.31708617610159984 0.035228577939480095 2.5414095842023174 0.00014050291445534264 3.8523146670845567 -1.033348807673161 SEPHS(ph)PGIPEIFR ddPTM_PC-9_Lapatinib_30min_R1 4 SEPHSPGIPEIFR 13 0 Q8ND82;Q9UJJ2 Q8ND82 ZNF280C Zinc finger protein 280C 1 SEPHS(1)PGIPEIFR;SEPHS(1)PGIPEIFR;SEPHS(1)PGIPEIFR;SEPHS(1)PGIPEIFR 135.72 2.956e-05 24750600.0 62763.0 54234.0 73946.0 65038.0 78277.0 85304.0 86793.0 88534.0 90161.0 72454.0 True False 61867.988110675455 54108.424505127055 67866.44531981474 69821.11148040778 73672.90075850324 81655.74677333645 91286.71685858941 92647.61284925729 80006.11874257955 84977.57736111351 0.7280507403472624 0.6367376687522225 0.7986394461613708 0.8216415865058367 0.8669687115864592 0.9609093281906486 1.0742447560097543 1.0902595217035884 0.9414968186559654 1.0 16.374794593771036 -6.272703387788715 0.9119643518805383 1.0370231064154796 0.685074888439083 0.856413449546513 0.05328134051352807 0.20626668818986793 0.3666855812109906 0.027033607160407945 0.043139632230419805 5.336992742277175e-07 6.272703387788715 -0.3519482179763965 SEPIPESNDGPVK ddPTM_PC-9_Lapatinib_30min_R1 1 SEPIPESNDGPVK 13 0 P30101 P30101 PDIA3 Protein disulfide-isomerase A3 0 212.09 4.3101e-10 9129800.0 33872.0 35008.0 32036.0 33154.0 33782.0 31197.0 35553.0 33323.0 32675.0 29558.0 False True 33388.979068635934 34926.941126885125 29402.123742536154 35592.255758501844 31795.009177967422 29862.777033758968 37393.76037783496 34871.308231592375 28994.797416996124 34667.06091644071 0.9631326736672203 1.0074964592778954 0.8481285394630129 1.0266880092399864 0.9171532958794547 0.8614164640532498 1.078653897657102 1.0058916824718418 0.8363788752350062 1.0 15.081277909167397 -7.243245632384246 24.9700898764861 0.9807221122225793 0.9396142216442571 0.06898687689273819 0.07691731139908128 2617.163248146977 3591942.045280991 0.02937855224455288 0.022713316844858656 5.7115550576307045e-08 7.243245632384246 -0.041107890578322204 SEPIS(ph)PPRDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEPISPPRDR 10 1 Q02078-3;Q02078-5;Q02078;Q02078-8;Q02078-7;Q02078-4;Q02078-6;Q02078-2 Q02078-3 MEF2A Myocyte-specific enhancer factor 2A 1 S(0.124)EPIS(0.876)PPRDR 62.528 0.027892 13981000.0 44026.0 36191.0 48738.0 63224.0 55818.0 63886.0 49650.0 61288.0 54942.0 44140.0 True False 51478.73224686361 39783.80330201346 49900.098759894296 59681.76425497359 44880.86359286571 60535.70569512463 44946.792565128584 59679.25494000371 55745.422809947886 52142.23258795223 0.9872751835094624 0.762986188497148 0.9569996581125297 1.1445954899285116 0.8607392005542106 1.1609726452164182 0.8620036069478506 1.1445473655033511 1.069103105930838 1.0 15.670164736005773 -5.520780087813125 24.980300756505507 1.0329131699117657 0.8713462307506773 0.24335594253303128 0.11303217548536533 94.7820876046121 1128188.6606049873 0.028385466287459506 0.050185172864013645 3.0145320959143777e-06 5.520780087813125 -0.16156693916108844 SEPQPEEGS(ph)PAGGQK ddPTM_PC-9_AZD4547_30min_R2 4 SEPQPEEGSPAGGQK 15 0 F8WE91;Q9Y6K1-3;Q9Y6K1 F8WE91 DNMT3A DNA (cytosine-5)-methyltransferase 3A 1 SEPQPEEGS(1)PAGGQK;SEPQPEEGS(1)PAGGQK;SEPQPEEGS(1)PAGGQK;S(0.027)EPQPEEGS(0.973)PAGGQK 215.49 1.3177e-49 28673900.0 47421.6 40742.2 59648.3 67397.0 64527.4 62296.0 50308.0 58817.5 49140.0 61279.0 True False 62500.682369444396 53911.31939285494 58857.32456849317 51859.662923270036 55568.88433400067 58400.621272062854 54785.31454049033 49728.606866690345 51737.44007870167 59133.64086187593 1.056939526443724 0.9116861165166666 0.9953272572201637 0.8769908662381128 0.9397169449416822 0.9876040172881413 0.9264661154292462 0.8409529016291452 0.874923974316916 1.0 15.851691486208347 -2.509630201636907 1.5001045683295657 0.923536398317399 138.4694810246789 0.336477828687069 0.05253250642257618 1549.5601774249178 4.526053747660214 0.01520331118358291 732746.9093372236 0.0030929279155750685 2.509630201636907 137.54594462636152 SEPQPEEGS(ph)PAGGQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SEPQPEEGSPAGGQK 15 0 F8WE91;Q9Y6K1-3;Q9Y6K1 F8WE91 DNMT3A DNA (cytosine-5)-methyltransferase 3A 1 SEPQPEEGS(1)PAGGQK;SEPQPEEGS(1)PAGGQK 215.49 1.0622000000000001e-17 15521100.0 39396.0 35444.0 34079.0 45849.0 49440.0 35674.0 40378.0 40256.0 36254.0 30406.0 True False 46064.96469353201 38962.646078764454 34891.5726053272 43280.229174463566 39752.58690800957 33803.19263951218 36553.10352859542 39199.32265475767 36784.14616417041 35918.36710623644 1.2824905029030076 1.0847554946894968 0.9714131074535691 1.2049609339548428 1.1067481656510885 0.9411116195658848 1.0176716391500096 1.0913447857698289 1.024104076206283 1.0 15.132434144403502 -6.588265700462303 10.408608414693017 1.0209030146472693 1.1249058384551915 0.327446726924877 0.08258393413692329 0.6290222309041104 96.34841513954669 0.027979820307459064 0.027975891275313684 2.5806808523787054e-07 6.588265700462303 0.10400282380792225 SEPQPEEGS(ph)PAGGQK ddPTM_PC-9_Lapatinib_30min_R1 4 SEPQPEEGSPAGGQK 15 0 F8WE91;Q9Y6K1-3;Q9Y6K1 F8WE91 DNMT3A DNA (cytosine-5)-methyltransferase 3A 1 SEPQPEEGS(1)PAGGQK;SEPQPEEGS(1)PAGGQK;SEPQPEEGS(1)PAGGQK;SEPQPEEGS(1)PAGGQK 255.93 1.3153999999999998e-62 23308000.0 85252.0 70177.0 76260.0 74154.0 78520.0 74105.0 73534.0 68647.0 72914.0 61091.0 True False 84036.29084669775 70014.50946816214 69990.19717211301 79607.53253049246 73901.60797625955 70935.7018971922 77341.23071537462 71836.5902281944 64701.65750154116 71650.49795135918 1.1728640169918543 0.977167102393236 0.9768277844995119 1.1110534442417275 1.031417925754383 0.9900238508509426 1.0794234921839436 1.0025972223802484 0.9030175553764423 1.0 16.128689110407564 -8.012312283105794 8.675618446631416 0.9517331431824475 1.0423595908050454 0.2749454738891104 0.06263451047761776 0.24126658178191512 131.81830573741408 0.03729797682085783 0.015728041134251323 9.720480131078826e-09 8.012312283105794 0.09062644762259786 SEPSDHS(ph)RHSPQQPSNGSLR ddPTM_PC-9_AZD4547_30min_R2 1 SEPSDHSRHSPQQPSNGSLR 20 1 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 S(0.021)EPS(0.206)DHS(0.691)RHS(0.082)PQQPSNGSLR 49.066 0.024694 6886000.0 0.0 815.64 12879.0 59119.0 28778.0 17249.0 7439.9 23107.0 6627.6 16448.0 True False 0.0 1079.2796792904699 12708.216045010899 45490.027929444936 24782.671444438685 16170.41730322673 8102.036687003932 19536.344096036282 6977.921405486433 15872.16052638157 0.0 0.06799828400781156 0.8006607559121022 2.866026200644497 1.5613924395010181 1.0187911895390307 0.5104558181312056 1.2308560049883799 0.4396327389638122 1.0 13.954210901455644 -3.497280694076741 10.319642341484668 0.9873228035984781 0.7323780191201302 0.0 0.7938334164877874 0.0 0.0 0.19834754292594972 0.0 0.00031821401697532277 3.497280694076741 -0.2549447844783479 SEPSGEINIDS(ph)SGETVGSGER ddPTM_PC-9_AZD4547_30min_R2 1 SEPSGEINIDSSGETVGSGER 21 0 P42695;E9PKK4;G3V1A9 P42695 NCAPD3 Condensin-2 complex subunit D3 1 SEPSGEINIDS(0.605)S(0.395)GETVGSGER 104.84 0.0012946 0.0 4393.5 4936.2 8024.2 8006.6 7728.6 5087.4 5514.6 7696.2 5307.1 5556.8 True False 5790.541609522954 6531.73011734787 7917.7938650808555 6160.802070736883 6655.61729534675 4769.284073768661 6005.388716804242 6506.929131082113 5587.622471340617 5362.258123358283 1.0798699869182062 1.2180931926598804 1.476578277832341 1.1489193412566434 1.2411967388057141 0.889417100790692 1.119936522757912 1.2134680915000309 1.0420278813137762 1.0 12.388624952756494 -6.625026790742454 24.998027056649118 1.0699134113459077 1.2410283502605162 0.342831275727177 0.1232156475236826 14.273001139855818 3466.6168200427255 0.0418161923995526 0.041816190505508874 2.371227424957311e-07 6.625026790742454 0.1711149389146085 SEPSLEPESFRS(ph)PTFGK ddPTM_PC-9_AZD4547_30min_R2 3 SEPSLEPESFRSPTFGK 17 1 Q9C0B5;Q9C0B5-2;H0YEF4 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5;Palmitoyltransferase 1 SEPSLEPES(0.111)FRS(0.857)PT(0.032)FGK;SEPS(0.009)LEPES(0.077)FRS(0.814)PT(0.1)FGK;SEPSLEPES(0.236)FRS(0.695)PT(0.069)FGK 88.574 0.0012751 43167300.0 58244.0 91512.0 92549.0 110729.0 98607.0 69064.0 92670.0 93825.0 59061.0 70407.0 True False 76764.38044954032 121091.4643853041 91321.73978955756 85202.13979599632 84917.1201307168 64745.417162157166 100917.45047442208 79326.50213401171 62182.84388457875 67942.07236022278 1.1298504414546329 1.782275108467225 1.3441117795962696 1.2540409327561015 1.2498458934324792 0.9529502841609359 1.485345485774511 1.167560826131851 0.9152332527464114 1.0 16.052017603333518 -6.546454523340811 0.3417365816728747 0.9853448018087624 1.5429903899466006 0.28950668794886536 0.21103525601472226 2.780496668740457 0.6124891057463353 0.24820560107342135 0.583013281560791 2.8414857123922303e-07 6.546454523340811 0.5576455881378383 SEPSLEPESFRS(ph)PTFGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SEPSLEPESFRSPTFGK 17 1 Q9C0B5;Q9C0B5-2;H0YEF4 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5;Palmitoyltransferase 1 SEPSLEPES(0.002)FRS(0.963)PT(0.036)FGK;SEPSLEPES(0.002)FRS(0.938)PT(0.06)FGK;S(0.002)EPS(0.007)LEPES(0.153)FRS(0.56)PT(0.278)FGK 90.853 0.0010925000000000002 41214900.0 36394.0 37349.0 42830.0 42087.0 110949.0 73989.0 70793.0 81098.0 76166.0 61001.0 True False 42554.78538573466 41056.76188905805 43851.229633679504 39729.001837895026 89209.33990406054 70108.88658980955 64086.97454306445 78969.26343043377 77279.78365808472 72059.99841634968 0.5905465767548423 0.5697580181981059 0.608537754612691 0.5513322607689777 1.2379869811906608 0.97292378754622 0.8893557584164998 1.095882114431416 1.072436654960441 1.0 16.13691099960829 -6.247878338289685 24.999588855247563 1.0381958766890105 0.581344220903844 0.8747912508359318 0.08610954710954015 269.2580457991327 496373.2686885793 0.026027560835216797 0.033417452349273284 5.650952564147539e-07 6.247878338289685 -0.4568516557851665 SEPSLEPESFRS(ph)PTFGK ddPTM_PC-9_Lapatinib_30min_R1 3 SEPSLEPESFRSPTFGK 17 1 Q9C0B5;Q9C0B5-2;H0YEF4 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5;Palmitoyltransferase 1 SEPSLEPES(0.261)FRS(0.729)PT(0.01)FGK;SEPSLEPES(0.022)FRS(0.847)PT(0.131)FGK;SEPS(0.016)LEPES(0.034)FRS(0.475)PT(0.475)FGK 117.27 6.057100000000001e-05 33757300.0 78646.0 86505.0 39535.1 19626.1 72448.0 59596.0 54038.0 53313.0 125045.0 39895.0 True False 77524.49361809007 86304.7029873513 36284.67668789928 21069.468864750343 68186.75107824817 57047.21800506137 56835.82323003531 55790.11660867518 110961.11531777449 46790.79759325398 1.6568320611244955 1.8444802701930048 0.7754660863727313 0.45029086804427576 1.4572684071553192 1.2191973836600318 1.2146795129269086 1.1923309598962397 2.3714303030767785 1.0 15.513937200554253 SEPSLEPESFRSPT(ph)FGK ddPTM_PC-9_AZD4547_30min_R2 1 SEPSLEPESFRSPTFGK 17 1 Q9C0B5;Q9C0B5-2;H0YEF4 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5;Palmitoyltransferase 1 SEPSLEPES(0.012)FRS(0.262)PT(0.727)FGK 114.31 0.00012156 31600000.0 36528.0 65438.0 61849.0 62010.0 53614.0 39392.0 52086.0 61856.0 48705.0 35979.0 True False 48143.14417040049 86589.55379016447 61028.84184858134 47714.55254494968 46170.621545004346 36928.81201279536 56721.553096047886 52297.57650947419 51279.446866771796 34719.38616115528 1.3866358105220182 2.4939828540817506 1.7577742177038138 1.3742913634323881 1.3298225184827988 1.0636366622780915 1.6337141685848426 1.5062932353333403 1.476968706438256 1.0 15.08345382070495 -5.649206334789589 4.017036169942834 1.3615574309085536 1.978396211656134 0.39394806681887107 0.3085499314469433 0.20189428210556035 5.937976789815797 0.08208535440387534 0.14820123370509652 2.2428161010356857e-06 5.649206334789589 0.6168387807475804 SEPSLEPESFRSPT(ph)FGK ddPTM_PC-9_Lapatinib_30min_R1 1 SEPSLEPESFRSPTFGK 17 1 Q9C0B5;Q9C0B5-2;H0YEF4 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5;Palmitoyltransferase 1 SEPSLEPES(0.049)FRS(0.438)PT(0.513)FGK 63.037 0.019336000000000002 5507100.0 16867.0 13304.0 8112.0 4337.7 8857.2 8221.9 6432.6 6511.4 23030.0 6987.1 True False 16626.47348697103 13273.195405395323 7445.062673225544 4656.708928143013 8336.23690992519 7870.268503185013 6765.648553046469 6813.943415034372 20436.118883348765 8194.810925274465 2.0289026358975044 1.6197073399775566 0.9085093897973234 0.5682509298391223 1.0172579923979135 0.9603965942535053 0.8256015440429298 0.8314948907507779 2.4937877236825092 1.0 13.000494947798208 -8.227620706553145 24.992550335562647 1.7468954715902285 1.072669569907294 0.19754894345324436 0.5239850967719337 859.1957223739138 634961.5203911347 0.3604076903839162 0.13620518203280652 5.920785034171922e-09 8.227620706553145 -0.6742259016829346 SEPVINNDNPLES(ph)NDEKEGQEATCSR ddPTM_PC-9_AZD4547_30min_R2 1 SEPVINNDNPLESNDEKEGQEATCSR 26 1 P23497;P23497-5;P23497-2;P23497-3;P23497-4;E9PHV6;P23497-7;P23497-6;H7C4B4 P23497 SP100 Nuclear autoantigen Sp-100 1 SEPVINNDNPLES(0.994)NDEKEGQEAT(0.003)CS(0.003)R 54.261 0.02742 0.0 2722.2 4505.9 3074.7 3697.9 3327.4 3666.6 3344.5 4029.4 3525.7 2157.4 True False 3587.8029747225196 5962.344057322993 3033.92746902671 2845.4062869854783 2865.4479451047764 3437.3269223729526 3642.15402084499 3406.7488164005995 3712.0613041407937 2081.8700826614545 1.7233558446336317 2.8639366629932814 1.4573087409701133 1.3667549722160963 1.376381729565756 1.6510765734135953 1.7494626831799585 1.6363887664140047 1.783041763775821 1.0 11.023664325946793 -5.288622786524659 24.860976934389214 1.5300467359696577 2.293646358986753 0.4693906252512674 0.3354231223276614 492.1331828607013 450086.65867643495 0.082942369503926 0.17272706552935205 5.144903264403071e-06 5.288622786524659 0.7635996230170954 SEPVINNDNPLES(ph)NDEKEGQEATCSR ddPTM_PC-9_Lapatinib_30min_R1 1 SEPVINNDNPLESNDEKEGQEATCSR 26 1 P23497;P23497-5;P23497-2;P23497-3;P23497-4;E9PHV6;P23497-7;P23497-6;H7C4B4 P23497 SP100 Nuclear autoantigen Sp-100 1 S(0.001)EPVINNDNPLES(0.969)NDEKEGQEAT(0.025)CS(0.005)R 46.66 0.017187 2434600.0 1138.8 2854.5 2581.8 2598.1 3144.9 3010.0 3524.6 2297.2 3539.7 2549.6 True False 1122.5605031696566 2847.890580629957 2369.534370036207 2789.1729410075286 2959.9231651112946 2881.2693166527074 3707.086541999751 2403.9362983409037 3141.0217113065373 2990.294962871548 0.37540126211886266 0.9523778142257775 0.7924082404769758 0.9327417447572183 0.9898432100721303 0.9635401699255299 1.2397059781821242 0.8039127671981997 1.0504053112841578 1.0 11.546072083628484 -4.605355350088292 2.3290258095505103 0.9732947919217881 2.692781987300525e-23 0.6828587790316348 0.12064522851778421 0.7381041005934302 2.973126962973804 0.03141794536098302 1.7672422357106563 2.481102177640278e-05 4.605355350088292 -0.9732947919217881 SEPVINNDNPLES(ph)NDEKEGQEATCSRPQIVPEPMDFR ddPTM_PC-9_Lapatinib_30min_R1 1 SEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFR 37 2 P23497;P23497-5;P23497-2;P23497-3;P23497-4;E9PHV6;P23497-7;P23497-6;H7C4B4 P23497 SP100 Nuclear autoantigen Sp-100 1 SEPVINNDNPLES(0.773)NDEKEGQEAT(0.114)CS(0.114)RPQIVPEPMDFR 45.408 0.019444 16122000.0 9876.1 11677.0 11036.0 11652.0 14649.0 12985.0 12635.0 11304.0 9555.3 11769.0 True False 9735.265002945072 11649.962623932748 10128.662680191948 12508.92694993253 13787.374621042112 12429.661819513418 13289.178476470195 11829.225107280865 8479.081492230234 13803.255968793244 0.7052875803328439 0.8440010567268537 0.7337879340273837 0.9062301661443526 0.9988494491598912 0.9004876709969529 0.9627567949558213 0.8569880276091874 0.6142812617110021 1.0 13.752720995536245 -5.767834994355262 24.9907486176889 0.8932442653700644 0.7693230713078585 0.23149396344266493 0.10847917290696335 236.5857231960205 924458.1528601204 0.031133552423984714 0.04746404194804046 1.7067307203130582e-06 5.767834994355262 -0.12392119406220592 SEPVINNDNPLES(ph)NDEKEGQEATCSRPQIVPEPMDFRK ddPTM_PC-9_AZD4547_30min_R2 1 SEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRK 38 3 P23497;P23497-5;P23497-2;P23497-3;P23497-4;E9PHV6;P23497-7;P23497-6;H7C4B4 P23497 SP100 Nuclear autoantigen Sp-100 1 SEPVINNDNPLES(0.673)NDEKEGQEAT(0.239)CS(0.088)RPQIVPEPMDFRK 46.803999999999995 0.0037134 17716000.0 20728.0 17361.0 22328.0 35634.0 27357.0 24118.0 19577.0 22326.0 20554.0 25799.0 True False 27319.072830816385 22972.60373714119 22031.916131143964 27419.131839811922 23558.952766193248 22609.897647354755 21319.31507432573 18876.0297004417 21640.442478177334 24895.784862604458 1.0973372794465261 0.9227507332636038 0.8849657182022703 1.1013563939089843 0.9463028740090358 0.9081817573591224 0.8563423564263328 0.7582018323429148 0.869241222865927 1.0 14.60361387796359 -6.861496649512549 2.3547744488714675 0.8527567772807509 0.989697957031645 0.30977691690503073 0.08452893314415343 0.3407924271198339 3.8567962097673933 0.033543414319309156 0.029091939121423598 1.3756354229623999e-07 6.861496649512549 0.13694117975089404 SEPVINNDNPLESNDEKEGQEAT(ph)CSRPQIVPEPMDFR ddPTM_PC-9_Lapatinib_30min_R1 1 SEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFR 37 2 P23497;P23497-5;P23497-2;P23497-3;P23497-4;E9PHV6;P23497-7;P23497-6;H7C4B4 P23497 SP100 Nuclear autoantigen Sp-100 1 SEPVINNDNPLES(0.102)NDEKEGQEAT(0.449)CS(0.449)RPQIVPEPMDFR 44.288999999999994 0.0042033999999999995 14627000.0 13996.0 17045.0 14703.0 14664.0 15285.0 15162.0 16435.0 18543.0 14671.0 15057.0 True False 13796.414473447949 17005.533349741683 13494.176095221288 15742.439477669996 14385.966351466213 14513.556604348289 17285.923882927393 19404.575474549638 13018.597487521043 17659.582387808638 0.7812423969307654 0.9629635048154661 0.764127701260764 0.8914389441359526 0.8146266449311748 0.8218516319144545 0.97884103391147 1.09881281722413 0.7371973584442452 1.0 14.108163606218659 -7.262630831419857 24.902579657552298 0.961947208052418 0.8428140559666216 0.23866561998593083 0.09949620281933284 143.582709564821 3000980.8382592164 0.037938746248237176 0.027212558252860383 5.462219754633498e-08 7.262630831419857 -0.11913315208579633 SEPVKEES(ph)SELEQPFAQDTSSVGPDR ddPTM_PC-9_AZD4547_30min_R2 2 SEPVKEESSELEQPFAQDTSSVGPDR 26 1 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 1 SEPVKEES(0.798)S(0.202)ELEQPFAQDTSSVGPDR;SEPVKEES(0.769)S(0.231)ELEQPFAQDTSSVGPDR 129.29 1.2963e-10 47763000.0 88404.0 92536.0 82512.0 98956.0 102726.0 99532.0 97200.0 98787.0 92464.0 81683.0 True False 116514.6330825693 122446.45235989282 81417.83696761688 76143.2230549595 88464.2680798321 93308.24830568509 105850.61169864936 83521.7390494283 97351.45827100278 78823.30303237011 1.4781749634967798 1.5534296032939414 1.0329158235627514 0.9659988877107828 1.1223111018768492 1.1837647588476023 1.3428847514190065 1.0596071952875243 1.235059360948421 1.0 16.26633458536339 -5.256555698590627 24.987283697219677 1.1250782949836107 1.5158023258251216 0.679107523098283 0.1093389808077746 238.5208104600046 1220378.0470254116 0.029633212410716724 0.07332667078598898 5.539164991795215e-06 5.256555698590627 0.39072403084151097 SEPVKEES(ph)SELEQPFAQDTSSVGPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SEPVKEESSELEQPFAQDTSSVGPDR 26 1 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 1 SEPVKEES(0.74)S(0.26)ELEQPFAQDTSSVGPDR;SEPVKEES(0.794)S(0.205)ELEQPFAQDTSSVGPDR;SEPVKEES(0.5)S(0.5)ELEQPFAQDTSSVGPDR 121.38 1.9911e-12 46348000.0 88958.0 115796.0 90558.0 117608.0 104418.0 82021.0 109622.0 93742.0 76421.0 75113.0 True False 104016.83239941153 127291.46161089667 92717.2461631276 111018.80505028037 83958.04247088471 77719.67437028169 99237.81056544863 91281.37182785921 77538.51255067196 88730.39230581932 1.1722796405644842 1.434586935806305 1.0449322239393142 1.251192541419647 0.9462151613340538 0.8759081567273145 1.11841960783194 1.0287497829745602 0.8738664457092303 1.0 16.437140726677022 -5.948447008741549 1.4079019296875852 0.9786609302081748 1.2748854741164461 0.5007367616547703 0.11760769907843446 0.3455204212788645 1.3902576734412 0.04043956187335675 0.07672001887616042 1.1260378561409482e-06 5.948447008741549 0.29622454390827135 SEPVKEES(ph)SELEQPFAQDTSSVGPDR ddPTM_PC-9_Lapatinib_30min_R1 2 SEPVKEESSELEQPFAQDTSSVGPDR 26 1 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 1 SEPVKEES(0.816)S(0.184)ELEQPFAQDTSSVGPDR;SEPVKEES(0.938)S(0.062)ELEQPFAQDTSSVGPDR 120.63 2.407e-12 43204000.0 120220.0 124969.0 108271.0 98378.0 117701.0 110093.0 123629.0 118280.0 105832.0 100894.0 True False 118505.64075435199 124679.64195857273 99369.37631814604 105613.04629938744 110778.05858906939 105384.5790293177 130029.90469865734 123775.72060236937 93912.08569963387 118333.3934671957 1.0014556101376746 1.0536302416877474 0.8397407815883616 0.8925041630675911 0.9361521320672613 0.8905734547241928 1.0988437066558405 1.0459914735453133 0.7936228561354333 1.0 16.852497731472155 SEPVKEES(ph)SELEQPFAQDTSSVGPDRK ddPTM_PC-9_AZD4547_30min_R2 1 SEPVKEESSELEQPFAQDTSSVGPDRK 27 2 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 1 S(0.01)EPVKEES(0.747)S(0.243)ELEQPFAQDTSSVGPDRK 47.54600000000001 0.009173700000000002 20041000.0 13484.0 10089.0 24967.0 42891.0 29698.0 15432.0 12424.0 32193.0 14267.0 17026.0 True False 17771.6315153767 13350.07194885189 24635.921266851998 33003.14260934424 25574.94532479462 14467.03460046349 13529.711931522856 27218.311571545244 15021.12449334222 16429.92492231106 1.08166236908628 0.8125461322542701 1.4994542813398728 2.008721449757055 1.5566075588127035 0.8805295622999435 0.823479839104447 1.656630307213642 0.9142539947303255 1.0 14.004038267356792 -6.756571993058586 24.986883132255294 1.081549454557724 1.3998720603307186 0.17446802141509576 0.3638343871801662 267.0415636181825 1370866.2102625945 0.1352293482622807 0.1311458524111494 1.7515720517904888e-07 6.756571993058586 0.31832260577299465 SEPVKEES(ph)SELEQPFAQDTSSVGPDRK ddPTM_PC-9_Lapatinib_30min_R1 2 SEPVKEESSELEQPFAQDTSSVGPDRK 27 2 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 1 S(0.01)EPVKEES(0.819)S(0.17)ELEQPFAQDTSSVGPDRK;S(0.006)EPVKEES(0.73)S(0.264)ELEQPFAQDTSSVGPDRK 95.59100000000001 9.503500000000001e-10 49674000.0 113193.0 95426.0 88478.0 84451.0 95019.0 91026.0 84620.0 80468.0 80607.0 76349.0 True False 111578.84706294582 95205.04695995618 81203.68037495665 90661.80826027734 89430.16923454154 87133.03017196979 89001.20955116005 84206.83704287665 71528.19083065979 89545.82292135243 1.246053064484592 1.0631991962771308 0.9068394004964069 1.0124627291649893 0.9987084412981221 0.9730552171986651 0.9939180482972308 0.9403770527279092 0.7987886927286667 1.0 16.450338515376515 -4.857711563325809 2.6715307456613595 0.9569768322063146 1.2787053086906615 0.6875894164278803 0.06064724145819514 0.22531420722608037 2.437606973274127 0.016085522421553092 0.151926343638035 1.387677148649979e-05 4.857711563325809 0.3217284764843469 SEPVKEESS(ph)ELEQPFAQDTSSVGPDR ddPTM_PC-9_AZD4547_30min_R2 2 SEPVKEESSELEQPFAQDTSSVGPDR 26 1 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 1 SEPVKEES(0.144)S(0.678)ELEQPFAQDT(0.165)S(0.009)S(0.003)VGPDR;SEPVKEES(0.062)S(0.938)ELEQPFAQDTSSVGPDR 112.37 7.675399999999999e-11 29295000.0 27974.0 32657.0 37081.0 47391.0 44574.0 41906.0 38741.0 43631.0 35171.0 47834.0 True False 36869.15010465351 43212.73660755831 36589.28171170503 36465.73713365118 38385.669503245874 39285.61119537474 42188.87394873846 36888.831490637436 37030.067256980416 46159.34621953647 0.7987364017094554 0.9361643989071268 0.7926733090560757 0.7899968288159469 0.8315904068632483 0.8510868201757049 0.9139833512391138 0.79916278092831 0.8022225245752683 1.0 15.494335169986222 -6.906189102328271 4.79757311718755 0.8646376575550854 0.8316919898309801 0.09207229409536344 0.06650587284681547 0.7628845066784523 30.055946942969214 0.023895418106382 0.02095600944474281 1.2411117798150374e-07 6.906189102328271 -0.03294566772410523 SEPVKEESS(ph)ELEQPFAQDTSSVGPDR ddPTM_PC-9_Lapatinib_30min_R1 1 SEPVKEESSELEQPFAQDTSSVGPDR 26 1 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 1 SEPVKEES(0.118)S(0.617)ELEQPFAQDT(0.249)S(0.014)S(0.001)VGPDR 92.565 0.00018659 0.0 8178.8 6915.1 7758.6 7003.4 6912.1 7615.6 6469.1 5155.9 6573.6 5090.0 True False 8062.168812191768 6899.088510812481 7120.717857062087 7518.453398657525 6505.54386771146 7289.898540830677 6804.038344450598 5395.461936538337 5833.211944923205 5969.799718001322 1.3504923436344305 1.1556649865503836 1.1927900756184984 1.259414679522061 1.0897423992457664 1.2211294993446316 1.1397431515053535 0.9037927889387767 0.9771202084608885 1.0 12.54346681570105 -7.632637579368732 4.4730541348801385 0.9565755346718807 1.2031810651651746 0.730811541219737 0.0679292323985241 0.1085632200968447 3.739689269440694 0.032945370084223595 0.01821895644185088 2.3300348707943184e-08 7.632637579368732 0.24660553049329392 SEPVKEESSELEQPFAQDT(ph)SSVGPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SEPVKEESSELEQPFAQDTSSVGPDR 26 1 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 1 SEPVKEESSELEQPFAQDT(0.333)S(0.333)S(0.333)VGPDR;SEPVKEES(0.016)S(0.068)ELEQPFAQDT(0.646)S(0.204)S(0.066)VGPDR 112.62 9.676700000000002e-11 23285000.0 35777.9 42567.0 50146.2 48643.0 50382.7 38921.5 43465.9 33965.2 30872.5 29070.8 True False 41834.39182426435 46792.77044449745 51341.87558852252 45917.69041273381 40510.57161023814 36880.388022615174 39348.495286135374 33073.64948910412 31323.951907468178 34341.10591567383 1.2182016481062268 1.3625877558922903 1.495055975034551 1.337105756741988 1.1796525047770368 1.0739429333806743 1.1458132822733613 0.9630921488177462 0.9121416178146852 1.0 15.067648879966008 -6.747496083948172 1.080332011046004 0.9781271170301189 1.3707119650311625 0.7890242672785139 0.0823057388416251 0.23397739492630007 0.5823897673762449 0.047772941405954734 0.043823139266645675 1.7885616565716438e-07 6.747496083948172 0.39258484800104365 SEPVKEESSELEQPFAQDT(ph)SSVGPDR ddPTM_PC-9_Lapatinib_30min_R1 2 SEPVKEESSELEQPFAQDTSSVGPDR 26 1 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 1 SEPVKEESSELEQPFAQDT(0.768)S(0.218)S(0.014)VGPDR;SEPVKEESSELEQPFAQDT(0.756)S(0.205)S(0.038)VGPDR 131.09 2.6042e-10 27036000.0 37513.2 41268.9 50190.0 39984.5 44737.1 40781.1 38075.3 41185.5 44846.3 35129.8 True False 36978.25488892166 41173.34439760365 46063.57193900269 42925.09351438185 42105.75173452268 39036.98741838727 40046.65273012629 43099.12868505981 39795.23744152512 41201.939122483884 0.8974882172170058 0.9993059859441269 1.1179952429439375 1.0418221673202182 1.0219361668719515 0.9474551016237194 0.9719603878612803 1.0460461231432827 0.9658583622295794 1.0 15.330424617359839 -6.6159496644150115 24.998946981916013 0.987852490406835 1.0219490943547467 0.05854164023794717 0.056147443486001536 51.02608066359487 13680.668916939361 0.01966625161915128 0.01966624959943891 2.4213096650282043e-07 6.6159496644150115 0.0340966039479117 SEPVKEESSELEQPFAQDT(ph)SSVGPDRK ddPTM_PC-9_AZD4547_30min_R2 2 SEPVKEESSELEQPFAQDTSSVGPDRK 27 2 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 1 SEPVKEESSELEQPFAQDT(0.451)S(0.451)S(0.098)VGPDRK;SEPVKEES(0.007)S(0.021)ELEQPFAQDT(0.673)S(0.221)S(0.077)VGPDRK 56.29 0.0017203 76223000.0 72191.0 77129.0 89579.0 92511.0 100020.0 105206.0 75329.0 101305.0 100955.0 108732.0 True False 95146.23633391874 102059.44091019886 88391.12393012118 71184.01823070226 86133.94947087186 98627.4521887221 82033.1350683906 85650.6400073119 106291.27519628276 104925.32577544505 0.9067995322458666 0.9726864334795625 0.842419342297689 0.6784255155237361 0.8209071435738081 0.9399775646138924 0.7818239730220429 0.816300920433798 1.0130183004984044 1.0 16.679003416992437 -8.266158874120196 23.88434255578664 1.0065092074304274 0.8438087061262965 0.40102292547209883 0.07898563334115645 248.507179528773 1257597.6192450817 0.07372450847576924 0.021582897838706597 5.418026512581384e-09 8.266158874120196 -0.16270050130413083 SEPVKEESSELEQPFAQDT(ph)SSVGPDRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEPVKEESSELEQPFAQDTSSVGPDRK 27 2 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 1 SEPVKEESS(0.001)ELEQPFAQDT(0.601)S(0.199)S(0.199)VGPDRK 53.443999999999996 0.0033765 3212400.0 6041.2 5386.5 5361.2 9378.7 8509.2 8035.6 5926.2 6257.7 4816.4 5676.7 True False 7063.855840861136 5921.236121861667 5489.031340464224 8853.241845155648 6841.883343803298 7614.198990134663 5364.827434027494 6093.442005581213 4886.830738266409 6705.840773267528 1.0533885428686014 0.8829968265077744 0.8185448366662613 1.3202284612018553 1.0202871757823562 1.1354577669795347 0.8000230866521747 0.9086768105011367 0.7287424356610875 1.0 12.7112025121504 -7.271377171205526 24.867770090282114 0.8517503114167448 1.0333985526235412 0.27199771545978935 0.14320162111662849 939.6122096261389 2351222.452172894 0.06112349540686625 0.04174151702247088 5.353315368362689e-08 7.271377171205526 0.18164824120679635 SEPVKEESSELEQPFAQDTSS(ph)VGPDRK ddPTM_PC-9_Lapatinib_30min_R1 1 SEPVKEESSELEQPFAQDTSSVGPDRK 27 2 Q14151;Q15424-2;Q15424;Q15424-4;Q15424-3 Q14151;Q15424-2 SAFB2;SAFB Scaffold attachment factor B2;Scaffold attachment factor B1 1 SEPVKEES(0.002)S(0.001)ELEQPFAQDT(0.311)S(0.311)S(0.374)VGPDRK 41.083999999999996 0.024805 41770000.0 40591.0 35907.0 37194.0 40460.0 40665.0 33791.0 27354.0 32182.0 36709.0 22907.0 True False 40012.16489652226 35823.85954761951 34136.05289299196 43435.56337060337 38273.164650466046 32345.837700668293 28770.25627585006 33677.293206167065 32574.44585709291 26866.444428341132 1.4892988539381804 1.3334053057586324 1.2705831984593463 1.6167216873991574 1.4245712622133238 1.203949327457228 1.0708620693217081 1.2535076346254899 1.2124583862958236 1.0 14.713517783705994 -6.8127759101890435 4.555881466010202 1.1540877381148444 1.424412233806998 0.6251271381724299 0.10843333814649204 0.15242503913939434 6.618945614741348 0.039727909748673434 0.03574135028702209 1.5389485111406056e-07 6.8127759101890435 0.27032449569215355 SEPVS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 1 SEPVSPSR 8 0 Q14814-6;Q14814-3;Q14814-5;Q14814-4;Q14814-2;Q14814 Q14814-6 MEF2D Myocyte-specific enhancer factor 2D 1 S(0.034)EPVS(0.586)PS(0.38)R 77.533 0.023407 13164000.0 19737.0 24104.0 31614.0 41002.0 37521.0 37916.0 38882.0 46837.0 39463.0 36402.0 True False 26012.9554448969 31895.146620589316 31194.777703779364 31549.622374585208 32311.856809603978 35545.10652612582 42342.42267558528 39599.41785718836 41548.93361468877 35127.577059906456 0.7405280301722629 0.9079802619518971 0.8880423961658355 0.8981439944115868 0.919843026875991 1.0118860878308604 1.2053897882958067 1.1273028535288854 1.1828010096976331 1.0 15.100316449015837 -6.875406467897997 2.086586117639287 1.1396985948008147 0.867362540305847 0.7576381988945081 0.06886637838034282 0.14728048186676546 1.3111402065938358 0.027548881602743026 0.023452250709713133 1.3322739374259725e-07 6.875406467897997 -0.27233605449496767 SEPVS(ph)PSRER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEPVSPSRER 10 1 Q14814-6;Q14814-3;Q14814-5;Q14814-4;Q14814-2;Q14814 Q14814-6 MEF2D Myocyte-specific enhancer factor 2D 1 SEPVS(0.562)PS(0.438)RER 58.04 0.037105 19751000.0 50165.0 41349.0 80767.0 64660.0 112700.0 76437.0 67724.0 75421.0 72032.0 77020.0 True False 58656.943696086724 45453.85545397902 82692.79159055311 61037.30983054839 90617.24402371944 72428.50916035195 61308.69244070021 73441.27866515517 73085.33172884436 90983.1163100156 0.6447014135701753 0.49958560771978494 0.9088806247170732 0.670864137282021 0.995978679329366 0.7960653811148792 0.6738469171774372 0.8071967815974953 0.803284550946943 1.0 16.473311229523148 -5.258890438128772 24.999515602507596 0.8182965409803814 0.5721435002109783 0.4566691307426034 0.11259071178137348 192.42670035771803 1887255.3217482914 0.027842062480796646 0.06699268964164504 5.5094666923872595e-06 5.258890438128772 -0.24615304076940314 SEPVSPS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 SEPVSPSR 8 0 Q14814-6;Q14814-3;Q14814-5;Q14814-4;Q14814-2;Q14814 Q14814-6 MEF2D Myocyte-specific enhancer factor 2D 1 S(0.01)EPVS(0.04)PS(0.951)R 69.27600000000001 0.04131 11216000.0 11324.0 18786.0 23682.0 30620.0 31100.0 24157.0 24814.0 31088.0 23166.0 21494.0 True False 14924.796446167738 24858.207119747403 23367.96120645609 23561.03207428414 26782.30182507619 22646.458971189506 27022.39792891244 26284.063931171342 24390.507465673643 20741.50160226443 0.7195620033864057 1.198476735022576 1.1266282284935878 1.1359366610039405 1.2912421838422856 1.0918427896617235 1.302817821346276 1.267220880878837 1.1759277574681881 1.0 14.340232722867448 -4.7605907870740785 24.99952444883529 1.1870615197972176 0.7195614586749696 0.6971909623526036 0.09014293470255602 10.974258254743871 323113.2796304008 0.021446013257660816 0.12597098365944126 1.7354384402844052e-05 4.7605907870740785 -0.46750006112224807 SEQLVNFT(ph)GKAEMGGPFSYV ddPTM_PC-9_AZD4547_30min_R2 1 SEQLVNFTGKAEMGGPFSYV 20 1 A0A087WTK1 A0A087WTK1 TMEM106C 1 S(0.415)EQLVNFT(0.585)GKAEMGGPFSYV 54.869 0.015272999999999998 78579000.0 51914.0 44247.0 71287.0 111040.0 95130.0 77196.0 54697.0 58979.0 39175.0 61062.0 True False 68421.57212171951 58548.977452755425 70341.68780190173 85441.44355089853 81922.84156332775 72368.9219166263 59564.9270378707 49865.15075259119 41245.710522652415 58924.23796582628 1.1611787353347074 0.9936314744827334 1.1937649128818113 1.4500220367796897 1.39030803607235 1.2281689914869567 1.0108730989854462 0.8462587294130303 0.6999786835864266 1.0 15.84657357557844 -7.482853525906315 2.5704623270749027 0.8298394618452 1.2404241547264383 0.6273511197926092 0.13503902639946821 0.20556908034456342 2.693383333283386 0.07997526457893683 0.04512941244400437 3.2896256106353875e-08 7.482853525906315 0.41058469288123833 SES(ph)ELIDELSEDFDR ddPTM_PC-9_Lapatinib_30min_R1 1 SESELIDELSEDFDR 15 0 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;P20810-2;E9PCH5;P20810-3;H0Y7F0;H0Y9H6;E7EQ12;E7EQA0;H0YD33;A0A0A0MR45;D6RC54 P20810-6 CAST Calpastatin 1 S(0.196)ES(0.804)ELIDELSEDFDR 169.92 9.9999e-21 0.0 0.0 0.0 549.13 0.0 1062.9 1090.3 2084.9 846.48 913.08 886.3 True False 0.0 0.0 503.98265110309916 0.0 1000.3823117418021 1043.6704106134366 2192.8459205059526 885.8105510271673 810.239315241341 1039.4957740794844 0.0 0.0 0.48483376620688645 0.0 0.9623726586360404 1.0040160206881543 2.109528460996204 0.8521540665344104 0.7794541694590733 1.0 10.021668177801166 -6.383015731121771 3.131049568839173 1.190221446864628 0.13334282559502017 0.6311707730702645 0.37339118876035715 0.1768298590867721 3.2885689265295026 0.12781149064115072 0.14726761140313 4.139846790930555e-07 6.383015731121771 -1.0568786212696077 SES(ph)ELIDELSEDFDRSECK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SESELIDELSEDFDRSECK 19 1 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;P20810-2;E9PCH5;P20810-3;H0Y7F0;H0Y9H6;E7EQ12;E7EQA0;H0YD33;A0A0A0MR45;D6RC54 P20810-6 CAST Calpastatin 1 S(0.2)ES(0.8)ELIDELSEDFDRSECK 65.887 0.0048419 3804900.0 9251.9 6855.9 8373.9 14116.0 17349.0 18888.0 16263.0 17677.0 17797.0 17567.0 True False 10818.063936645565 7536.50844293537 8573.565534192598 13325.126284689466 13949.587990838565 17897.480029576334 14722.45090607625 17212.99748032968 18057.247456383862 20751.758039704506 0.5213083111294607 0.36317445628055744 0.4131488772078359 0.6421203571858536 0.6722123477032022 0.8624560866280795 0.7094555978297196 0.8294717704107726 0.8701550693601373 1.0 14.340945942887327 -6.215198390415762 1.05325497167172 0.8509483196619311 0.4081115839757054 0.8244160916270109 0.08302959329375775 0.2096371399510209 0.48502894101657396 0.03579412028193736 0.05759581694435533 6.092585177822371e-07 6.215198390415762 -0.44283673568622567 SES(ph)ELIDELSEDFDRSECK ddPTM_PC-9_Lapatinib_30min_R1 1 SESELIDELSEDFDRSECK 19 1 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;P20810-2;E9PCH5;P20810-3;H0Y7F0;H0Y9H6;E7EQ12;E7EQA0;H0YD33;A0A0A0MR45;D6RC54 P20810-6 CAST Calpastatin 1 S(0.225)ES(0.761)ELIDELS(0.014)EDFDRSECK 47.916000000000004 0.035868000000000004 6525800.0 2410.0 5098.3 3196.1 4728.7 6711.9 7615.8 6605.3 7756.9 8493.5 8618.1 True False 2375.6329580601287 5086.4951995886195 2933.3289953027784 5076.464372480773 6317.119238103115 7290.089987296904 6947.290114018881 8117.3138919556695 7536.872589479926 10107.727102103576 0.23503137095635698 0.5032283863827349 0.2902065880560138 0.5022359944229481 0.6249792039585659 0.7212392967930171 0.6873246619977543 0.8030800406420084 0.7456545386856938 1.0 13.303170998236757 -5.986628910104147 0.25606539320540667 1.010728905198471 4.014858472600254e-15 0.8762171485350255 0.07805707317987835 1.6984946440359228 0.16200090006068218 0.125100871317261 0.5363339963553161 1.031266926668575e-06 5.986628910104147 -1.010728905198467 down SES(ph)ENWR ddPTM_PC-9_AZD4547_30min_R2 1 SESENWR 7 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1;C9IYH5;C9JH78 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 SES(1)ENWR 109.44 0.009612299999999999 92082000.0 73470.0 70902.0 74071.0 139690.0 90952.0 62669.0 89615.0 146060.0 106590.0 106020.0 True False 96831.93172906591 93819.68493582087 73088.77014286836 107486.62868898599 78324.88474579847 58750.29752309787 97590.56139274158 123489.78312489993 112224.12979220213 102308.27206997664 0.9464721646636254 0.9170293177432441 0.7143974642918144 1.0506152289960236 0.7655772418111602 0.5742477742456049 0.9538872998069184 1.2070361528580562 1.096921368346865 1.0 16.642563272421903 -7.530873381212851 11.341161177861249 1.1074599946550159 0.8283669509208474 0.4630779615543299 0.1320178263280983 0.26385571235641797 353.0823140415137 0.06266226689027243 0.03697485449475286 2.9452802066444883e-08 7.530873381212851 -0.27909304373416843 SES(ph)ENWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SESENWR 7 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1;C9IYH5;C9JH78 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 S(0.01)ES(0.99)ENWR;S(0.001)ES(0.999)ENWR 87.258 0.018062 93292000.0 43214.0 40613.0 31095.0 49787.0 59989.0 56273.0 62367.0 84142.0 75878.0 52532.0 True False 50529.276684594646 44644.79023803357 31836.422728444177 46997.595801631825 48234.58608463968 53321.944817045136 56459.1462620216 81933.3616558183 76987.57220292717 62055.63575691681 0.8142576587649024 0.7194316792259662 0.5130303209389914 0.7573461334878582 0.7772797022591681 0.8592603099888764 0.9098149680261487 1.3203210418593752 1.2406217624536386 1.0 15.921274618258654 -7.372049660359872 1.6045090955070853 1.2075509593802376 0.7096409845853868 0.7362063792311632 0.1181049232279526 0.18985472186409671 0.9485685747632233 0.07215641576531961 0.03971024229623047 4.2457101266216615e-08 7.372049660359872 -0.4979099747948508 SES(ph)ENWR ddPTM_PC-9_Lapatinib_30min_R1 1 SESENWR 7 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1;C9IYH5;C9JH78 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 S(0.006)ES(0.994)ENWR 98.044 0.012289 82261000.0 62928.0 71986.0 73362.0 46194.0 94217.0 84479.0 108140.0 75992.0 88886.0 109240.0 True False 62030.63518041816 71819.32083980658 67330.45954550947 49591.26085866663 88675.34129774888 80866.03010016748 113738.96006691614 79522.86574243497 78874.72266892475 128121.98844684985 0.4841529227916328 0.5605542164185199 0.5255183779280856 0.38706284112378636 0.6921164928261707 0.6311643386155684 0.8877395788631522 0.6206808581918337 0.6156220616388978 1.0 16.967158568390644 -6.399634853862084 5.380818725140806 0.7284806197648711 0.49767992349954976 0.5026094409649435 0.12264570781707142 0.21278309822126684 8.478335194706641 0.03758467699848151 0.04258733906829881 3.9844203187445836e-07 6.399634853862084 -0.23080069626532135 SES(ph)ETSTMAAK ddPTM_PC-9_Lapatinib_30min_R1 1 SESETSTMAAK 11 0 A0A087WVF1;Q96B23-2;Q96B23 A0A087WVF1 C18orf25 Uncharacterized protein C18orf25 1 S(0.207)ES(0.634)ET(0.082)S(0.066)T(0.011)MAAK 69.815 0.029743000000000002 8068400.0 24710.0 23177.0 22228.0 22397.0 34263.0 36842.0 33544.0 34792.0 33467.0 29124.0 True False 24357.630868740966 23123.335080490637 20400.499642561295 24044.15009420178 32247.71770364978 35266.353542896664 35280.74418794745 36408.56333444054 29697.594036866394 34158.04459470933 0.7130862190077961 0.6769513698706325 0.5972385095404754 0.7039088560100402 0.9440738802901077 1.032446498660494 1.0328677945871647 1.0658854675797158 0.8694172745903082 1.0 15.059937768610283 -6.285073799864315 3.171000531856839 1.00504686048765 0.6612320211238747 0.8879100665858708 0.055735307391056504 0.07641534296052122 1.5783211241365356 0.017899206194900225 0.021872828821743483 5.187118864859448e-07 6.285073799864315 -0.3438148393637752 SES(ph)FSSEDLIPSR ddPTM_PC-9_AZD4547_30min_R2 1 SESFSSEDLIPSR 13 0 Q9P219-3;Q9P219-2;Q9P219;A0A0A0MR69 Q9P219-3 CCDC88C Protein Daple 1 SES(0.971)FS(0.025)S(0.005)EDLIPSR 144.51 9.225700000000001e-05 2254700.0 6230.0 6231.8 5698.5 11718.0 8357.6 6990.3 5031.3 10117.0 6435.6 7734.8 True False 8211.010407949929 8246.107480508992 5622.934166666246 9016.59614129529 7197.291502677072 6553.195435952565 5479.075953080405 8553.650115532047 6775.7726774622 7464.007006289888 1.100080747650765 1.104782923376148 0.7533398832460665 1.208010139017426 0.964266445169725 0.8779728409191222 0.734066292872342 1.14598634598332 0.9077929149520203 1.0 12.865734625076696 -6.511245588696973 24.81454036792421 0.9288748268029235 1.033065026683982 0.10935667684825678 0.1454883286910238 1274.1064949521826 2717787.305363596 0.04648153127479366 0.04982210616990145 3.0814449346455903e-07 6.511245588696973 0.10419019988105849 SES(ph)FSSEDLIPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SESFSSEDLIPSR 13 0 Q9P219-3;Q9P219-2;Q9P219;A0A0A0MR69 Q9P219-3 CCDC88C Protein Daple 1 S(0.045)ES(0.952)FS(0.003)S(0.001)EDLIPSR 135.81 5.2592e-05 1771400.0 11056.0 12270.0 11277.0 10320.0 13840.0 8843.3 12926.0 11165.0 8027.3 9976.0 True False 12927.562434046344 13488.084510394987 11545.886448260653 9741.803857891422 11128.151351271295 8379.541780260073 11701.555703864087 10871.930580295357 8144.684076340405 11784.569830027456 1.0969906089492132 1.144554676576053 0.9797461099378757 0.8266575698901625 0.9442984777362355 0.7110604715420953 0.9929556931342673 0.922556422262723 0.6911312159725587 1.0 13.524611476668468 -5.479549264956896 3.286389700743423 0.8685527039009642 1.1192774019708513 0.49601039509035194 0.10069392907790889 0.1918228717924029 4.142231959002329 0.02665572006451702 0.05849887302914967 3.314749662344182e-06 5.479549264956896 0.2507246980698872 SES(ph)FSSEDLIPSR ddPTM_PC-9_Lapatinib_30min_R1 2 SESFSSEDLIPSR 13 0 Q9P219-3;Q9P219-2;Q9P219;A0A0A0MR69 Q9P219-3 CCDC88C Protein Daple 1 S(0.001)ES(0.998)FSSEDLIPSR;S(0.005)ES(0.971)FS(0.009)S(0.016)EDLIPSR 142.38 8.130399999999999e-05 4011200.0 30111.0 33249.0 32823.0 26970.1 30803.3 25400.2 31187.0 30951.4 31503.0 34642.0 True False 29681.611618318868 33172.01398331248 30124.41964044403 28953.57112361617 28991.51045561787 24313.89265675816 32801.71026083705 32389.515037640915 27954.800398703264 40629.82354243653 0.7305375468174847 0.8164449434210658 0.7414361425660649 0.7126186775922152 0.7135524579706132 0.5984247662646895 0.8073308570138565 0.7971857176246685 0.6880364707837184 1.0 15.310251478427961 -11.245515906939639 2.8793994200568895 1.0420436276251979 0.7354028321961749 0.6286331349174354 0.06133659709769366 41121990.20064681 35629867.69181407 12423950.516626747 0.015658680313963023 5.68177580491902e-12 11.245515906939639 -0.306640795429023 SES(ph)GGSEYGTGPGR ddPTM_PC-9_AZD4547_30min_R2 1 SESGGSEYGTGPGR 14 0 Q12873;Q12873-3;Q12873-2;A0A5F9ZHX5 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 S(0.055)ES(0.944)GGS(0.001)EYGTGPGR 101.61 0.0075731999999999996 0.0 10135.0 8479.6 12023.0 15127.0 13639.0 12221.0 11725.0 10707.0 12066.0 13146.0 True False 13357.719178904103 11220.464872384231 11863.567164311355 11639.70385982026 11745.460276276981 11456.818938067925 12768.502285665278 9052.479172383286 12703.784126772785 12685.762541330978 1.0529693532717366 0.8844927402532785 0.9351875479033396 0.9175407329198702 0.9258773556583267 0.9031241835672802 1.0065222523332538 0.7135936166934991 1.0014206150700908 1.0 13.630922621973143 -4.753758622641744 24.93685854667129 0.9145350873444482 1.052969609589192 0.1903214395460352 0.08080186991593931 418.70259611973904 1359273.044737888 0.018688669902303206 0.19442580399998874 1.762955610630105e-05 4.753758622641744 0.13843452224474384 SES(ph)GGSEYGTGPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SESGGSEYGTGPGR 14 0 Q12873;Q12873-3;Q12873-2;A0A5F9ZHX5 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 S(0.025)ES(0.975)GGSEYGTGPGR 88.78 0.023898 0.0 10219.0 10203.0 12738.0 11418.0 13960.0 12211.0 12877.0 9114.1 13678.0 10269.0 True False 11948.874865549886 11215.88641072209 13041.722229134015 10778.286477655456 11224.6382126985 11570.633663763061 11657.197338593372 8874.864532187183 13878.014873766293 12130.688410640734 0.9850120999784838 0.9245877918093913 1.0751015760733038 0.8885139996012934 0.925309251439723 0.9538315775725962 0.9609675019241259 0.7316043600957036 1.1440418221931121 1.0 13.566373804569793 -4.729815956623206 21.192463917852233 0.9483500810950767 0.9850135326862577 0.0021238887623582503 0.10434210701678971 3847.27377851628 2577299.948628375 0.024402175414992146 2.1384398290639703 1.862876410862781e-05 4.729815956623206 0.03666345159118101 SES(ph)LDPDSSMDTTLILK ddPTM_PC-9_AZD4547_30min_R2 1 SESLDPDSSMDTTLILK 17 0 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 S(0.146)ES(0.854)LDPDSSMDTTLILK 79.652 0.043472000000000004 0.0 9318.2 8624.9 9083.8 11677.0 10358.0 11251.0 8840.1 14363.0 8580.8 8139.2 True False 12281.193769399526 11412.730255887855 8963.342876750514 8985.048057851604 8919.970492094513 10547.47319140842 9626.851774457118 12143.528378905496 9034.3635699496 7854.2490853796735 1.5636369098938316 1.4530644663577237 1.1412093987998633 1.143972894184991 1.135687243316313 1.3429002666903016 1.2256870987676038 1.5461094048456039 1.1502517263893064 1.0 12.939257636237032 -5.092169735221329 4.3292776842259855 1.2311625647773248 1.5428120637189955 0.4200619385676583 0.14062645884965394 0.2129094935997241 6.8047866117037135 0.036601157832682786 0.11334950869857845 8.087797421835123e-06 5.092169735221329 0.3116494989416707 SES(ph)LDPDSSMDTTLILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SESLDPDSSMDTTLILK 17 0 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 S(0.074)ES(0.926)LDPDSSMDTTLILK 96.435 0.011362 0.0 5396.4 7046.3 7153.3 6950.8 7359.7 6460.4 8043.7 6519.5 7209.7 7713.3 True False 6309.9039362416515 7745.810096625605 7323.861801041318 6561.3692107976485 5917.6196170485055 6121.605251115782 7281.742504655083 6348.370032981238 7315.128223087646 9111.660231550797 0.6925086950007695 0.8500986537891652 0.8037900464814416 0.7201068788844542 0.6494556937667255 0.6718430116521026 0.7991674754772695 0.6967303292322996 0.8028315408159833 1.0 13.153498235461853 -8.630680482406438 4.486551987847599 0.9999833566121059 0.7385126762973185 0.6314544106271587 0.060828181123018944 0.49530486653333977 19.567184908108615 0.06297630541297305 0.0164269368415819 2.340558592821402e-09 8.630680482406438 -0.2614706803147874 SES(ph)LELPQAAPPQIYHEK ddPTM_PC-9_AZD4547_30min_R2 2 SESLELPQAAPPQIYHEK 18 0 B0QY58;B0QY55;B0QY57;B0QY56;H0YGT9;Q15040 B0QY58 JOSD1 Josephin-1 1 S(0.176)ES(0.824)LELPQAAPPQIYHEK;S(0.146)ES(0.854)LELPQAAPPQIYHEK 135.76 4.3001000000000004e-05 16956600.0 66021.0 69725.0 89394.0 102786.0 86165.0 94366.0 80128.0 99475.0 74957.0 82263.0 True False 87014.30467789124 92262.24270331021 88208.57715099806 79090.27572786972 74202.47706616374 88465.27910234188 87259.23677149584 84103.42445809541 78919.07399225167 79382.99740890844 1.0961327679486994 1.1622418617939017 1.111177204567224 0.9963125393271448 0.9347401772188142 1.114410919086991 1.09921821573474 1.0594639557999008 0.9941558843606387 1.0 16.276542417388903 -5.637769965651839 5.915071511869399 1.0337156846181697 1.130746014479788 0.40558882769240834 0.052548544544158124 0.2255696474951046 10.751209278191798 0.015533181492501718 0.02719802938475122 2.3026611534179803e-06 5.637769965651839 0.09703032986161841 SES(ph)LELPQAAPPQIYHEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SESLELPQAAPPQIYHEK 18 0 B0QY58;B0QY55;B0QY57;B0QY56;H0YGT9;Q15040 B0QY58 JOSD1 Josephin-1 1 S(0.181)ES(0.819)LELPQAAPPQIYHEK;S(0.19)ES(0.81)LELPQAAPPQIYHEK 109.56 0.00013943 16194300.0 69818.0 85912.0 84059.0 90898.0 107649.0 75317.0 78449.0 92538.0 79427.0 68045.0 True False 81636.80843164306 94440.77558737199 86063.2853555328 85805.27975529195 86555.95121481233 71367.24393199912 71017.74279842427 90108.9755521158 80588.46961387889 80381.01985607651 1.0156229490222326 1.1749138758934596 1.0706916322986506 1.0674818496820226 1.0768207640285248 0.8878618865471389 0.8835138310708506 1.1210230439158066 1.0025808301284782 1.0 16.294567261648396 -6.6082469161135915 11.949442624056218 0.9806156895637841 1.0860038499919176 0.3333052303381756 0.07213936683624006 0.6790301732658972 91.48532725548345 0.025014295653937393 0.02501080769829944 2.4646376804961936e-07 6.6082469161135915 0.10538816042813348 SES(ph)LELPQAAPPQIYHEK ddPTM_PC-9_Lapatinib_30min_R1 1 SESLELPQAAPPQIYHEK 18 0 B0QY58;B0QY55;B0QY57;B0QY56;H0YGT9;Q15040 B0QY58 JOSD1 Josephin-1 1 S(0.191)ES(0.809)LELPQAAPPQIYHEK 131.64 2.3021999999999997e-05 10080000.0 64599.0 73907.0 71284.0 65773.0 74996.0 73258.0 53322.0 64835.0 77736.0 59378.0 True False 63677.8064139943 73735.87288233243 65423.30468419746 70610.16583229587 70584.88272780893 70124.92611273885 56082.75225345022 67847.47079180414 68980.55308363006 69641.40818378828 0.9143670134576308 1.0587935368529393 0.9394310998356183 1.0139106556540467 1.013547608651605 1.0069429659962437 0.8053075564676138 0.9742403630430645 0.9905106011295151 1.0 16.08765775484214 SES(ph)LIDASEDSQLEAAIR ddPTM_PC-9_AZD4547_30min_R2 2 SESLIDASEDSQLEAAIR 18 0 C9JAT7;O94888 C9JAT7 UBXN7 UBX domain-containing protein 7 1 S(0.008)ES(0.991)LIDASEDSQLEAAIR;S(0.001)ES(0.999)LIDASEDSQLEAAIR 173.34 4.2158e-19 1081300.0 1964.69 2815.9 4037.17 3534.9300000000003 5492.0 3236.9 3837.63 6463.2 4993.3 4945.9 True False 2589.4205519093343 3726.0846070742423 3983.634487959983 2720.0065026240786 4729.530598820528 3034.496131301211 4179.171635525597 5464.460949560812 5257.2356439760115 4772.745546414793 0.5425431812208098 0.7807004523577031 0.8346630779326634 0.5699039423267185 0.9909454742193982 0.6357967550942819 0.8756326091310107 1.1449302914683193 1.1015118222519025 1.0 12.220603707431614 -7.582979414223682 4.101547270576175 1.089617618995459 0.7385144725816314 0.6055295634216412 0.1282728544581175 0.14385387272534042 4.940289915267324 0.06119563595735344 0.034249075874484614 2.6122851750924262e-08 7.582979414223682 -0.35110314641382756 SES(ph)LIDASEDSQLEAAIR ddPTM_PC-9_Lapatinib_30min_R1 1 SESLIDASEDSQLEAAIR 18 0 C9JAT7;O94888 C9JAT7 UBXN7 UBX domain-containing protein 7 1 S(0.009)ES(0.991)LIDASEDSQLEAAIR 101.9 0.00049742 1005000.0 1378.4 1194.4 2234.9 581.79 2728.9 2780.7 2923.7 2097.2 3277.6 3723.5 True False 1358.7437632323988 1191.634440183718 2051.1551489634803 624.5767773945462 2568.3914672238266 2661.775943128299 3075.0748802260323 2194.643568205008 2908.4421733418963 4367.102013748122 0.31113167472500586 0.2728661790890894 0.4696833603854951 0.14301859114541157 0.5881226175020059 0.6095062434421574 0.7041454196731277 0.5025400279856129 0.6659890618963783 1.0 12.092460516950288 -7.746813694681902 0.1649516026964088 1.2155988974075476 7.000451669729223e-16 0.7385042797509289 0.11965082331057435 2.160026758560503 0.35038550580967337 0.9968894191873997 1.1467099179336375 1.7913741598087665e-08 7.746813694681902 -1.215598897407547 down SES(ph)LSNCSIGK ddPTM_PC-9_AZD4547_30min_R2 2 SESLSNCSIGK 11 0 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 S(0.001)ES(0.965)LS(0.03)NCS(0.005)IGK;S(0.037)ES(0.962)LS(0.001)NCSIGK 161.48 9.3249e-05 70266000.0 48655.0 56508.0 69562.0 78640.0 75172.0 70398.0 65412.0 79936.0 81443.0 64802.0 True False 64126.277913130645 74773.10592583222 68639.56242899655 60510.76297588852 64735.665363171276 65996.00193127464 71233.54128016533 67583.72794654263 85747.91071082023 62533.301704193735 1.0254740460766376 1.1957325758927204 1.0976481420042035 0.9676566137852022 1.0352190528719492 1.0553736990165783 1.1391297011171269 1.0807637867298183 1.3712359394749443 1.0 15.932337071858694 -8.054801335884243 24.999945350308252 1.199078755912734 1.0757220115040782 0.156423027456837 0.1021918805428556 493.20011723683064 224990.99148335715 0.06583011313046207 0.02488177764640847 8.814519931080538e-09 8.054801335884243 -0.12335674440865585 SES(ph)LSNCSIGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SESLSNCSIGK 11 0 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 S(0.009)ES(0.99)LS(0.001)NCSIGK;S(0.016)ES(0.983)LS(0.001)NCSIGK;S(0.02)ES(0.936)LS(0.043)NCS(0.001)IGK;SES(0.5)LS(0.5)NCSIGK 146.67 0.00023624 104610000.0 86177.0 112403.0 126217.0 119448.0 141305.0 113226.0 125271.0 103293.0 98225.0 75558.0 True False 100765.06402666555 123561.62699445245 129226.49196063809 112755.71581564116 113617.29961643009 107288.2292370187 113404.42399649971 100581.66819798012 99661.35480155666 89256.06728320131 1.1289435787815663 1.3843498907744025 1.44781745257288 1.2632834859044106 1.2729364296987544 1.2020272963248875 1.2705514308251773 1.1268888632393328 1.116577929490668 1.0 16.445662620869044 -7.984269484554847 0.6104531713322108 1.000378980027185 1.3196249461512324 0.578143585140044 0.08279722255851114 0.5260634386387448 0.4317209120370128 0.0826605431719415 0.04215065448350761 1.0368848176005196e-08 7.984269484554847 0.31924596612404743 SES(ph)LSNCSIGK ddPTM_PC-9_Lapatinib_30min_R1 2 SESLSNCSIGK 11 0 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 S(0.023)ES(0.922)LS(0.047)NCS(0.008)IGK;S(0.138)ES(0.817)LS(0.045)NCSIGK 137.09 8.7963e-05 64295000.0 44670.0 50592.0 57640.0 49409.0 47831.0 48489.0 42260.0 47097.0 56769.0 34571.0 True False 44032.997608525264 50474.85733236319 52901.061696834346 53042.70268359224 45017.6746193641 46415.238503379755 44448.01602023191 49285.298556051566 50375.077415928165 40546.551287038055 1.0859862605035353 1.2448619113137502 1.3046994138252588 1.3081927068985755 1.1102713594720786 1.1447394915240992 1.0962218637430967 1.215523811313815 1.2424010382365638 1.0 15.307291589856947 -6.273819252867456 24.60190555836358 1.1441978919604339 1.241484445869459 0.25000858054340547 0.08462535286137578 949.3699089157662 1886631.4978236342 0.026789792929858225 0.0305827719668754 5.323297611799039e-07 6.273819252867456 0.09728655390902508 SES(ph)LSNCSIGKK ddPTM_PC-9_AZD4547_30min_R2 3 SESLSNCSIGKK 12 1 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 S(0.227)ES(0.773)LSNCSIGKK;S(0.15)ES(0.811)LS(0.022)NCS(0.017)IGKK;S(0.009)ES(0.864)LS(0.125)NCS(0.002)IGKK 149.82 0.00024498 69842000.0 84141.0 62933.9 113911.0 174477.0 154555.0 103694.0 91653.0 116312.0 97826.0 119677.0 True False 110896.08775847749 83276.05243550896 112400.46571187483 134254.0232927784 133097.70606349382 97209.99778774388 99809.93944461239 98338.6529838651 102996.88264426275 115487.14465684377 0.9602461649562117 0.721085040962384 0.9732725321580975 1.1625018844452184 1.1524893654525594 0.8417386894151012 0.8642515125054454 0.8515116836256247 0.8918471657629571 1.0 16.817372742770644 SES(ph)LSNCSIGKK ddPTM_PC-9_Lapatinib_30min_R1 3 SESLSNCSIGKK 12 1 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 S(0.007)ES(0.993)LSNCSIGKK;S(0.001)ES(0.999)LSNCSIGKK;S(0.002)ES(0.975)LS(0.023)NCSIGKK 154.23 0.00010139 43253000.0 107910.0 67201.0 73884.0 69519.0 71186.0 61211.2 49879.0 50678.0 69470.0 45955.3 True False 106371.18361172953 67045.40021331716 67809.54272048756 74631.65916858558 66998.97943706073 58593.33966627642 52461.490560178594 53032.68488913476 61645.55704846886 53898.612373411815 1.9735421549405683 1.2439170001042672 1.2580944060433363 1.3846675430442321 1.243055739039978 1.0871029343082033 0.9733365712037857 0.9839341414157776 1.1437318018761946 1.0 15.717960510639159 -1.5228787452803376 0.5929139676434934 1.0708904396209846 48.81814641952387 0.795861193698955 0.12659829075779672 79.66596602867988 0.6327608285955394 0.0624167201395547 4917.276851917036 0.029999999999999995 1.5228787452803376 47.74725597990289 SES(ph)LTAESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SESLTAESR 9 0 Q15751;H0YNB1 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 S(0.017)ES(0.982)LT(0.001)AESR 86.189 0.011855 7301800.0 25821.0 32746.0 28547.0 9410.4 20936.0 30862.0 32951.0 42180.0 29380.0 27983.0 True False 30191.985312003475 35996.806469225296 29227.668745100385 8883.165796928437 16833.74109033352 29243.542390554037 29829.64273541897 41072.819693404206 29809.626918500766 33056.09638669387 0.9133560405564618 1.0889612024399578 0.8841839158257493 0.26873003070332874 0.5092477010416038 0.8846641190919776 0.9023945957341276 1.2425187539668878 0.9017890851292438 1.0 15.01262874555681 -7.27629638316647 2.594916040587482 1.0492880882031506 0.7375565527133287 0.24148606501820602 0.23018737694173202 0.45585968552884937 6.075698425155403 0.12136853523816743 0.08022318448365223 5.293020997324531e-08 7.27629638316647 -0.3117315354898219 SES(ph)LTAESR ddPTM_PC-9_Lapatinib_30min_R1 1 SESLTAESR 9 0 Q15751;H0YNB1 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 S(0.018)ES(0.969)LT(0.013)AESR 82.494 0.015693000000000002 9833600.0 24536.0 14902.0 25607.0 19345.0 22596.0 26678.0 24550.0 28065.0 30448.0 28163.0 True False 24186.112140648667 14867.495334576151 23501.691305878503 20767.695833028218 21266.947705445258 25537.044129455437 25821.07887592744 29369.00235631963 27018.625608345767 33030.93702516134 0.7322260377362252 0.4501081917007327 0.7115054377045396 0.6287346864307364 0.6438493612592686 0.7731250285150122 0.7817240805569098 0.8891362159646808 0.8179793866508935 1.0 15.011530276280931 -7.493632010000634 0.4719073708170521 0.9878786417757103 0.583778381773085 0.6980297157961518 0.07872019278802724 0.5014557954184261 0.25591319409226176 0.07615569329135015 0.06388063591292657 3.208987238519673e-08 7.493632010000634 -0.4041002600026252 SES(ph)MPVQLNK ddPTM_PC-9_AZD4547_30min_R2 2 SESMPVQLNK 10 0 Q92609;Q92609-2;C9J3F6 Q92609 TBC1D5 TBC1 domain family member 5 1 S(0.004)ES(0.996)MPVQLNK;S(0.001)ES(0.999)MPVQLNK 90.913 0.0074029 43892000.0 211976.0 313750.0 343660.0 539360.0 389700.0 355940.0 296230.0 410950.0 333950.0 285440.0 True False 279379.95862529665 415163.5517843469 339102.843856545 415018.8850289322 335596.8817116457 333683.0155319447 322593.8961264502 347447.1201915484 351601.91522756295 275446.83248117473 1.0142790755976137 1.507236616390283 1.2311009017673884 1.5067114088425628 1.2183726299868847 1.2114244063951982 1.1711657499219843 1.2613945023865705 1.2764783390696388 1.0 18.071414347069435 -6.490365088946068 24.802931591386187 1.2013191768162719 1.3275878596272728 0.1403925986368374 0.1492078245482033 1140.771161171924 870234.2026240716 0.04337371559640984 0.04913834445089192 3.2332174275917465e-07 6.490365088946068 0.1262686828110009 SES(ph)MPVQLNK ddPTM_PC-9_Lapatinib_30min_R1 2 SESMPVQLNK 10 0 Q92609;Q92609-2;C9J3F6 Q92609 TBC1D5 TBC1 domain family member 5 1 S(0.006)ES(0.994)MPVQLNK;S(0.055)ES(0.945)MPVQLNK 120.57 0.00069465 13279900.0 75405.0 68719.0 82811.0 53083.0 65153.0 73549.0 70089.0 78941.0 64227.0 62940.0 True False 74329.71087241669 68559.88537758282 76002.59923970411 56986.90089969695 61320.82863572645 70403.48072109299 73717.86547188916 82608.88704828876 56993.0789197065 73819.09513772157 1.0069171226461457 0.928755429061724 1.0295791230969285 0.771980485447276 0.8306906027677857 0.953729933830045 0.9986286791291122 1.1190720625086017 0.7720641768010921 1.0 16.171706432923777 -6.992417605111085 24.818723815808962 0.9814803998073062 0.9109251913830506 0.06244830251127187 0.10619698840004306 445.3115632709963 1457585.8071055429 0.037899699189373665 0.03336258218967106 1.0176124105590926e-07 6.992417605111085 -0.07055520842425556 SES(ph)PFRETEPLVSPHQDK ddPTM_PC-9_AZD4547_30min_R2 1 SESPFRETEPLVSPHQDK 18 1 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 S(0.222)ES(0.713)PFRET(0.064)EPLVS(0.001)PHQDK 46.368 0.045798 6960900.0 6806.4 4616.7 9704.9 15767.0 15321.0 12595.0 10745.0 13536.0 11831.0 13887.0 True False 8970.69361808514 6108.957990510903 9576.20668493099 12132.161747721684 13193.943609710363 11807.4326589449 11701.284184176839 11444.322226336053 12456.362506534791 13400.820356873837 0.6694137656642565 0.4558644790262683 0.7145985417242726 0.9053297801651818 0.9845623818800496 0.8810977495783217 0.8731767065420561 0.8540016149433557 0.9295223855564488 1.0 13.710033700274813 -5.593073277539463 3.3054832513311547 0.9117719957455228 0.5633601603107843 0.8280675096203077 0.06587516270325987 0.08615315662568397 1.8870591831878936 0.017837132765933173 0.0347062756030154 2.5522706273973855e-06 5.593073277539463 -0.3484118354347385 SES(ph)PFRETEPLVSPHQDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SESPFRETEPLVSPHQDK 18 1 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 S(0.211)ES(0.631)PFRET(0.157)EPLVS(0.001)PHQDK 51.568000000000005 0.028837 5196100.0 10270.0 9796.2 15179.0 14790.0 16310.0 14476.0 15165.0 12943.0 13794.0 8775.7 True False 12008.508158253966 10768.70199516963 15540.924926678068 13961.364249826953 13114.172582314655 13716.853076458445 13728.461414907846 12603.259964242068 13995.711154315843 10366.664941597026 1.1583771855178728 1.0387817158013277 1.4991248404604005 1.3467556179814324 1.2650329354904726 1.3231693272364322 1.3242891028358945 1.21574875191254 1.3500688247535613 1.0 13.33966421911186 -10.719065169772161 4.257139025511546 0.9999009199013944 1.2816749175878834 0.33758991483855705 0.11771070513981569 87474968.79668443 18.006421598475136 91412.99609301543 0.029493243480281792 1.9095666895011122e-11 10.719065169772161 0.28177399768648903 SES(ph)PFRETEPLVSPHQDK ddPTM_PC-9_Lapatinib_30min_R1 2 SESPFRETEPLVSPHQDK 18 1 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 S(0.168)ES(0.696)PFRET(0.136)EPLVSPHQDK;S(0.076)ES(0.905)PFRET(0.019)EPLVSPHQDK 132.67 1.8879e-05 12477700.0 38499.0 24707.0 35598.0 27229.0 30114.0 29154.0 19166.5 21976.1 31626.0 19954.0 True False 37949.997200148064 24649.792459493554 32671.269852253798 29231.511493281236 28342.753726401952 27907.15138129335 20158.847587595257 22997.189833697357 28063.94684345582 23403.022312966277 1.6215853103349878 1.0532738947070317 1.3960278042444336 1.2490485674188212 1.2110723712252691 1.1924592904323983 0.8613779587103325 0.9826589713994303 1.1991590858718786 1.0 14.514407233903812 -6.83163066260834 1.8838939576630562 1.012231937617044 1.3089693964297104 0.43883632498538383 0.15654988725457383 0.32957892729112753 2.407106098728709 0.06362373816074163 0.05539311228143791 1.473565134854344e-07 6.83163066260834 0.29673745881266633 SES(ph)PGVR ddPTM_PC-9_AZD4547_30min_R2 2 SESPGVR 7 0 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 S(0.082)ES(0.918)PGVR;S(0.003)ES(0.997)PGVR 90.709 0.015746 22643300.0 37745.0 33183.0 45527.0 55744.0 62337.0 62522.0 47387.0 55552.0 52106.0 51710.0 True False 49747.124855227914 43908.755821067694 44923.28223318666 42893.08203621474 53682.58356494454 58612.48945633607 51604.351199217126 46967.71485796544 54860.21678349266 49899.64863929903 0.9969433896183592 0.8799411823210086 0.9002725161035869 0.8595868549349627 1.075810852957915 1.1746072578590292 1.0341626164993785 0.9412433982746622 1.0994108832318887 1.0 15.606742036632516 -6.267877209938811 24.906820692721528 1.0562859199421581 0.9064603934065948 0.5325263850632751 0.06652752572770515 397.3587200685551 1537307.714336965 0.02150317820745609 0.024963045019046774 5.396631823819647e-07 6.267877209938811 -0.14982552653556336 SES(ph)PGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SESPGVR 7 0 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 S(0.014)ES(0.986)PGVR;S(0.016)ES(0.984)PGVR 90.601 0.015819 22945000.0 25629.0 35910.0 44124.0 37099.0 60733.0 51226.0 39767.0 37213.0 39333.0 39116.0 True False 29967.48350417634 39474.90747907777 45176.08350120183 35020.4633065808 48832.804625488425 48539.61838178087 35999.98187185235 36236.19818043268 39908.17071427471 46207.42115791438 0.6485426529596215 0.8542979999721653 0.9776802593421532 0.7578969444518008 1.056817355346488 1.0504723519604389 0.7790952398927872 0.7842073258448046 0.8636744859205211 1.0 15.495836954305865 -4.78496628233886 3.7055056256345136 0.9022044546212251 0.6224632932591412 0.34838790362133376 0.10616122053681752 0.31492875712458446 7.527935329604381 0.028012390999708203 0.24189217958502768 1.640717149898398e-05 4.78496628233886 -0.27974116136208393 SES(ph)PGVR ddPTM_PC-9_Lapatinib_30min_R1 2 SESPGVR 7 0 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 S(0.031)ES(0.969)PGVR;S(0.046)ES(0.954)PGVR 80.455 0.025381 20132600.0 37151.0 40134.0 43056.0 32952.0 42144.0 42684.0 40041.0 44359.0 43702.0 34549.0 True False 36621.21992734098 40041.07218882559 39516.101880966315 35375.400004649564 39665.17277829194 40858.5048212638 42114.1270578823 46420.0810804911 38779.8205575383 40520.748616351215 0.9037646434933665 0.9881622022320667 0.9752066097076129 0.8730194088856156 0.9788854878728962 1.008335389064759 1.0393225321826387 1.1455879435988343 0.957036132888463 1.0 15.306373207566109 -6.807124455265461 2.3187292196683362 1.0455730715091602 0.9410747555741171 0.3941026025293328 0.05478465237468731 0.28838258240635745 3.1783773271122184 0.02118243778692928 0.01899984879931453 1.5591056477073016e-07 6.807124455265461 -0.1044983159350431 SES(ph)PGVRR ddPTM_PC-9_AZD4547_30min_R2 1 SESPGVRR 8 1 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 S(0.027)ES(0.973)PGVRR 77.192 0.010952 3103300.0 7729.4 7304.9 12125.0 21878.0 18431.0 14965.0 12380.0 15572.0 12631.0 17101.0 True False 10187.188418492482 9666.066069894747 11964.214577665733 16834.365111730513 15872.173792217996 14029.23618428824 13481.79601676215 13165.705208961654 13298.64887330243 16502.299195139294 0.6173193382345831 0.5857405659413726 0.7250028881545039 1.020122403106655 0.9618159024103199 0.8501382757876861 0.8169647063927417 0.7978103568040734 0.8058664260080505 1.0 14.010379422586626 -5.542105869791316 5.702755735545977 0.882914771002821 0.6124031327002285 0.7070839239165737 0.07637011036948287 0.09540702210047712 10.036736564441359 0.022765016736180164 0.04175169452483716 2.870080845067885e-06 5.542105869791316 -0.2705116383025925 SES(ph)PGVRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SESPGVRR 8 1 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 S(0.108)ES(0.892)PGVRR;S(0.024)ES(0.976)PGVRR 66.568 0.022325 7554000.0 17088.6 16678.7 25708.0 32066.0 33162.0 35881.0 30267.0 38765.0 32803.0 23826.0 True False 19981.36246476523 18334.451110311733 26320.976218132924 30269.445979374654 26664.14415540886 33999.33719510949 27399.89064589622 37747.45982491259 33282.68181782098 28145.46519348778 0.7099318603335241 0.6514175901613418 0.9351764498183884 1.0754644050572777 0.9473691044757837 1.2079863296406328 0.9735099582662406 1.3411560109387175 1.1825237774191004 1.0 14.780614873084422 -5.399175307642577 0.7986296586731301 1.1501985527302692 0.553177272903257 0.6705152286419215 0.11649928633703788 0.7041127499499059 0.6132928769051357 0.048926552363753484 0.3206679544044506 3.988638641695925e-06 5.399175307642577 -0.5970212798270121 SES(ph)PGVRR ddPTM_PC-9_Lapatinib_30min_R1 2 SESPGVRR 8 1 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 S(0.028)ES(0.972)PGVRR;S(0.348)ES(0.652)PGVRR 64.84100000000001 0.024485 6414600.0 49369.0 28538.0 37124.0 38154.0 26316.0 25566.0 17551.6 21638.0 32044.0 19062.1 True False 48664.98900683421 28471.922014369495 34071.80802278415 40959.97243801289 24768.14461924664 24472.60177725685 18460.33596736163 22643.380473402627 28434.867281720708 22356.95858634833 2.1767267143640083 1.2735149955394693 1.5239911945620892 1.8320905448661513 1.1078494654622044 1.094630187855712 0.8257087338630189 1.0128113082084964 1.2718575816964517 1.0 14.448436318587586 -6.3352870964641985 5.810613716934431 1.0381998677108102 1.6573182015789156 0.6367359104728668 0.2394635883548698 0.15380793798671705 9.281007212043503 0.07416001919789125 0.08455688161695318 4.620754589431324e-07 6.3352870964641985 0.6191183338681054 SES(ph)PIPVAEQGTLMR ddPTM_PC-9_AZD4547_30min_R2 2 SESPIPVAEQGTLMR 15 0 P86452 P86452 ZBED6 Zinc finger BED domain-containing protein 6 1 S(0.001)ES(0.999)PIPVAEQGTLMR;S(0.003)ES(0.975)PIPVAEQGT(0.022)LMR 130.47 1.0780999999999999e-05 25783000.0 57222.0 55193.0 77387.0 108493.0 92040.0 80679.0 66646.0 89008.0 66894.0 78037.0 True False 75417.40570846082 73033.05789205883 76360.79781623253 83481.61505014074 79261.83472604559 75634.12937602354 72577.36488959032 75253.8588003636 70429.8802731923 75304.94838261434 1.0014933590456114 0.9698307941330451 1.0140209834319727 1.1085807353054922 1.0525448383992888 1.004371306275076 0.9637794918978559 0.9993215640758272 0.9352623139099376 1.0 16.200457048862276 -7.024736585325628 4.878231283431886 0.9752261341172354 1.0296376202833457 0.3166723647928549 0.037827153361312926 0.27301351736101664 17.09830311100082 0.015969797668356718 0.012873505118466688 9.446336556563722e-08 7.024736585325628 0.05441148616611036 SES(ph)PIPVAEQGTLMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SESPIPVAEQGTLMR 15 0 P86452 P86452 ZBED6 Zinc finger BED domain-containing protein 6 1 S(0.008)ES(0.992)PIPVAEQGTLMR 97.223 0.0021944000000000004 11319000.0 24807.0 30764.0 34598.0 35270.0 41074.0 35771.0 37429.0 31640.0 33170.0 23554.0 True False 29006.335139416373 33818.04660780696 35422.94753364568 33293.936246882804 33025.84455217607 33895.105788753426 33883.454157506516 30809.483525351072 33655.04849852521 27824.1537466386 1.0424875956171926 1.215420490978723 1.2731006253128214 1.196583966220536 1.1869487515380728 1.218189997704719 1.2177712381135737 1.107292743056853 1.209562339432912 1.0 14.764050189161829 -10.729527684771243 3.1535387871187726 0.9994127616471433 1.188746502716907 0.4471226486372285 0.061693447644246384 8365504.726613504 12105008.60752538 49230.016628934325 0.015371076317386526 1.8641133436861428e-11 10.729527684771243 0.18933374106976375 SES(ph)PIPVAEQGTLMR ddPTM_PC-9_Lapatinib_30min_R1 2 SESPIPVAEQGTLMR 15 0 P86452 P86452 ZBED6 Zinc finger BED domain-containing protein 6 1 SES(1)PIPVAEQGTLMR;SES(1)PIPVAEQGTLMR 110.57 0.00045137 16633200.0 123715.0 119657.0 128288.0 99365.0 122955.0 110150.0 103548.0 103749.0 129201.0 96761.0 True False 121950.80141344781 119379.9415682043 117740.65584600091 106672.63357192272 115723.02863883077 105439.14127219123 108909.20877574469 108569.55729434539 114649.02283315423 113486.00992407175 1.0745888545648883 1.0519353147412258 1.03749048825292 0.9399628521902608 1.019711845682615 0.9290937388911258 0.9596707898058167 0.9566778968348986 1.010248072955077 1.0 16.792154933563793 -5.615855336352991 5.051869274777838 0.9714924822609533 1.059190063035448 0.6340562593561986 0.02853640644678218 0.12139862041368128 5.0997586874107 0.007607413339372396 0.013514568808774826 2.4218356267047802e-06 5.615855336352991 0.08769758077449474 SES(ph)PKEPEQLR ddPTM_PC-9_AZD4547_30min_R2 2 SESPKEPEQLR 11 1 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8W646 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 S(0.001)ES(0.999)PKEPEQLR;S(0.285)ES(0.715)PKEPEQLR 121.24 0.0038006999999999997 95373000.0 90074.0 91269.0 77194.0 92116.0 93388.0 93814.0 94373.0 101055.0 78595.0 89212.0 True False 118715.65834441116 120769.91938742819 76170.35712233638 70880.07937801302 80422.68819421936 87947.79574960352 102772.01417527396 85439.27176288357 82749.3712451274 86088.71503401958 1.3789921048014067 1.4028542456430402 0.8847891049626682 0.8233376389693285 0.934183860944362 1.0215949409263374 1.1937919404960529 0.9924561161021004 0.9612104352170598 1.0 16.393536513437603 -5.254448331672156 24.986611587408884 0.9785520201282785 1.390923235016777 0.7653493120033344 0.09179936217018128 277.382911320155 991384.4495927317 0.026904442727074956 0.06797990169153612 5.566108507137589e-06 5.254448331672156 0.4123712148884986 SES(ph)PKEPEQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SESPKEPEQLR 11 1 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8W646 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 SES(1)PKEPEQLR;S(0.002)ES(0.998)PKEPEQLR 107.93 0.010853 231746000.0 108450.0 135805.0 82909.4 116903.0 120889.0 92349.0 126460.0 90469.0 87396.3 87710.0 True False 126808.44301486318 149286.8228960221 84886.27453165043 110353.30391463947 97201.6682589476 87506.05586887684 114480.79330888558 88094.28460982897 88674.30554994436 103611.12868802193 1.2238882504280932 1.4408377245414619 0.8192775776745669 1.0650719214430968 0.9381392664066663 0.8445623262377708 1.104908273449976 0.850239599986263 0.8558376563674636 1.0 16.660819443105623 -5.2606231615409875 24.997475948538696 0.9370368273320088 1.3323630049701214 0.6995538070436609 0.10422034914767683 35.3869613643005 1083717.1744346782 0.025776148410381214 0.060497034159004086 5.487529127395304e-06 5.2606231615409875 0.3953261776381126 SES(ph)PKEPEQLR ddPTM_PC-9_Lapatinib_30min_R1 3 SESPKEPEQLR 11 1 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8W646 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 S(0.001)ES(0.999)PKEPEQLR;S(0.044)ES(0.956)PKEPEQLR;S(0.001)ES(0.999)PKEPEQLR 119.88 0.0044469999999999996 83115900.0 91471.0 122507.0 105383.0 113750.0 114082.0 95413.0 107879.0 110796.0 90854.0 100613.0 True False 90166.60676627292 122223.34256830765 96718.81653014387 122115.5544588762 107371.92105384168 91332.40840856633 113464.44676399896 115943.98664068387 80621.06578496606 118003.82299160476 0.7640990306957065 1.035757482001266 0.8196244331594649 1.0348440530402474 0.909902055134947 0.7739783855567465 0.9615319562322252 0.982544325270992 0.6832072363511625 1.0 16.848474074038222 -6.537908979304825 24.97338222458566 0.8795412603231557 0.9226939656104935 0.016081884335540808 0.11944440791284446 1090.950751866271 1812650.009027524 0.03755291205047598 0.03756456138229301 2.897950884998089e-07 6.537908979304825 0.043152705287337834 SES(ph)PPAELPSLR ddPTM_PC-9_AZD4547_30min_R2 4 SESPPAELPSLR 12 0 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 S(0.001)ES(0.999)PPAELPSLR;S(0.01)ES(0.989)PPAELPS(0.001)LR;S(0.063)ES(0.937)PPAELPSLR;S(0.008)ES(0.992)PPAELPSLR 132.79 7.6777e-05 116342000.0 195971.7 195775.0 219611.0 249311.0 241402.0 228978.0 214901.0 233529.0 184254.9 223756.0 True False 258286.62413541647 259055.44016121322 216698.81464872195 191836.20076655303 207887.49920183409 214659.96946247548 234026.77268159966 197442.45901256154 193994.2378501665 215922.37054602566 1.1962013175488018 1.1997619306703258 1.003595940989036 0.8884498640943808 0.9627881477779586 0.9941534493144095 1.0838468107301318 0.9144140948122604 0.898444368499627 1.0 17.720153195351166 -5.304620754875885 4.175696317819956 0.9648930735385679 1.2014786879831933 0.7442682143247062 0.05421539815074994 0.1031462367654428 3.965161005836571 0.015367051860312782 0.036497173168868066 4.9588302875422994e-06 5.304620754875885 0.23658561444462545 SES(ph)PPAELPSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SESPPAELPSLR 12 0 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 S(0.011)ES(0.988)PPAELPSLR;S(0.008)ES(0.992)PPAELPSLR;SES(1)PPAELPSLR;S(0.031)ES(0.967)PPAELPS(0.003)LR;SES(1)PPAELPSLR;S(0.003)ES(0.997)PPAELPSLR 158.34 7.0787e-05 187948900.0 102916.4 134201.0 129419.3 126857.0 135753.0 118299.0 132436.1 116238.5 105612.8 86038.2 True False 120338.11382844472 147523.58837648877 132505.14693742833 119749.6135659433 109153.17416106442 112095.19218651268 119890.79385366819 113187.36253987098 107157.18740021205 101636.24458198358 1.1840078736023694 1.4514860223656803 1.3037194308231719 1.1782176137898208 1.0739591433154283 1.102905687312094 1.1796066880153153 1.113651562052451 1.0543206101419367 1.0 16.633055448928886 -5.870208564595961 2.8907828679684133 1.099457479171316 1.330674871401146 0.6431283928462777 0.07468913859778346 0.1558623381150928 2.620469151666563 0.021403641075952065 0.034857842691619456 1.3483152152492165e-06 5.870208564595961 0.23121739222982995 SES(ph)PPAELPSLR ddPTM_PC-9_Lapatinib_30min_R1 3 SESPPAELPSLR 12 0 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 S(0.002)ES(0.998)PPAELPSLR;S(0.279)ES(0.721)PPAELPSLR;S(0.002)ES(0.998)PPAELPSLR 143.55 8.5614e-05 195782100.0 260410.0 258121.0 256243.0 221702.0 264757.0 241802.0 264544.0 229098.0 227102.0 215685.0 True False 256696.50564665455 257523.33668340748 235175.68966658405 238006.70465619134 249184.5137922894 231460.69212799263 278240.793896267 239742.72944336748 201523.38126992038 252965.86486780268 1.0147476054953164 1.0180161533572385 0.9296736134319324 0.9408649059452 0.985051931502737 0.9149878472692415 1.0999143858467733 0.9477275899206975 0.7966425880236229 1.0 17.94858319568663 -8.008292497505654 24.999639315662783 0.8896092124401176 0.9837859183507586 0.2089575780555567 0.06778658235912714 511.7747598535179 1542854.3611424689 0.038255974559465944 0.016962848393983626 9.81086958003158e-09 8.008292497505654 0.09417670591064098 SES(ph)PPAELPSLRR ddPTM_PC-9_AZD4547_30min_R2 1 SESPPAELPSLRR 13 1 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 S(0.237)ES(0.763)PPAELPSLRR 80.387 0.0058738 23572000.0 15928.0 16639.0 20473.0 35662.0 27644.0 20611.0 14920.0 24295.0 12522.0 21950.0 True False 20992.77267701869 22017.231356620723 20201.51464317945 27440.676872407617 23806.107770173843 19322.190911751753 16247.851096130153 20540.765993560453 13183.887355830342 21181.537181060034 0.9910882528294437 1.039453896495668 0.9537322277649946 1.2954997853953838 1.1239084097947636 0.9122185395037874 0.7670761077084881 0.9697485984127469 0.6224235400450079 1.0 14.370519671571849 -6.901930194941868 4.477827107419549 0.8374179102639738 1.0824311411150664 0.43728575232145184 0.1302174501640373 0.2050484558499201 7.254078902480326 0.04691398991095678 0.041102108860303015 1.2533426111250506e-07 6.901930194941868 0.2450132308510926 SES(ph)PPAELPSLRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SESPPAELPSLRR 13 1 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 S(0.413)ES(0.587)PPAELPSLRR;S(0.177)ES(0.823)PPAELPSLRR;S(0.057)ES(0.943)PPAELPSLRR 124.16 7.2005e-05 32203900.0 79246.0 64666.0 82358.0 110167.0 108098.0 143851.0 108977.0 128190.0 111142.0 88358.0 True False 92660.78262015505 71085.61311729449 84321.72706445427 103994.70015623287 86916.97288798599 136307.20032478753 98653.90963484441 124825.14832853226 112767.2414899934 104376.60595845703 0.8877543178309035 0.6810492874771891 0.8078604040642516 0.9963410785518724 0.832724652136896 1.305917155220004 0.9451726153474438 1.195911164022846 1.080388085572316 1.0 16.67143886977658 -6.196319709903225 1.2725440566334607 1.1003694255079899 0.7795449112532067 0.4846289741580392 0.12712045096476543 0.3502334628908136 1.1536524831971882 0.04721249618742089 0.07216921193295961 6.363269104973339e-07 6.196319709903225 -0.3208245142547832 SES(ph)PPAELPSLRR ddPTM_PC-9_Lapatinib_30min_R1 3 SESPPAELPSLRR 13 1 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 S(0.034)ES(0.892)PPAELPS(0.074)LRR;S(0.081)ES(0.919)PPAELPSLRR;S(0.199)ES(0.801)PPAELPSLRR 77.24 0.0074911000000000005 39607700.0 109624.0 59387.0 76499.0 50069.0 42773.2 56115.0 35671.0 40310.9 66553.0 42005.0 True False 108060.74165742054 59249.493050226396 70209.54751467954 53751.24128528767 40257.36447134673 53715.09226045401 37517.86984045653 42183.89157617549 59057.100305840635 49265.50828185572 2.193436045340039 1.2026566885548147 1.4251258124243775 1.091052201831926 0.8171511037910746 1.0903184425326848 0.7615443572775277 0.8562560916825381 1.198751466603484 1.0 15.588290321366102 -1.522878745395815 0.7391299288162396 0.9530416153399868 194.53242365738146 0.8037134196961075 0.17415868558326414 145.8207438218054 0.6586100850738679 0.06459137159897037 46932.214435522736 0.0299999999920231 1.522878745395815 193.57938204204146 up SES(ph)PPPLSDPK ddPTM_PC-9_AZD4547_30min_R2 5 SESPPPLSDPK 11 0 Q15059;Q15059-2 Q15059 BRD3 Bromodomain-containing protein 3 1 S(0.034)ES(0.966)PPPLSDPK;S(0.001)ES(0.999)PPPLSDPK;SES(1)PPPLSDPK;SES(1)PPPLSDPK;S(0.36)ES(0.64)PPPLSDPK 216.84 9.713500000000001e-09 271484000.0 289417.0 291248.0 356102.0 476697.0 438868.0 373460.0 346314.0 413626.0 350581.0 380247.0 True False 381445.58575243026 385388.2203349404 351379.85480708693 366801.8715452331 377938.7536131049 350107.4871623304 377135.27510088513 349709.60587991046 369111.9959347029 366934.6682681792 1.0395463245616399 1.0502911108232331 0.9576087657933597 0.999638091642927 1.0299892223235863 0.9541412067023594 1.0277995177747847 0.9530568684895167 1.0059338292475881 1.0 18.485163692394053 -5.241222808715032 24.808219839502335 0.991040264359969 1.0449187323625106 0.3915084093942882 0.026877410424219244 716.3669574432149 879066.9507698851 0.006423279371543543 0.016945857082160537 5.738219953217165e-06 5.241222808715032 0.0538784680025417 SES(ph)PPPLSDPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SESPPPLSDPK 11 0 Q15059;Q15059-2 Q15059 BRD3 Bromodomain-containing protein 3 1 S(0.007)ES(0.993)PPPLSDPK;S(0.026)ES(0.974)PPPLSDPK;S(0.061)ES(0.939)PPPLSDPK 158.01 0.00093107 221342000.0 187992.0 202235.0 188473.0 224886.0 248762.0 219500.0 227655.0 196852.0 184342.0 179618.0 True False 219815.33258875163 222311.55427544663 192966.9111078325 212286.36651024895 200018.87185295884 207989.03359233425 206089.8703205309 191684.84358193493 187037.65300919945 212181.3215446939 1.0359787138117607 1.0477432822880166 0.9094434406526493 1.0004950716905254 0.9426789803966172 0.9802419556922376 0.9712912937867629 0.9034011202609953 0.8814991425614334 1.0 17.694938134926524 -3.044150037889494 0.492151704979747 0.9390343601234771 1.642232714735944 0.35578252461072746 0.043178998456634046 24.171169464579705 1.1445297055523864 0.0248979433547241 14.214720517479604 0.0009033373393337991 3.044150037889494 0.7031983546124668 SES(ph)PPPLSDPK ddPTM_PC-9_Lapatinib_30min_R1 6 SESPPPLSDPK 11 0 Q15059;Q15059-2 Q15059 BRD3 Bromodomain-containing protein 3 1 S(0.001)ES(0.999)PPPLSDPK;SES(1)PPPLSDPK;S(0.001)ES(0.999)PPPLSDPK;S(0.003)ES(0.997)PPPLSDPK;S(0.004)ES(0.996)PPPLSDPK;S(0.41)ES(0.59)PPPLSDPK 182.71 7.9854e-05 324188500.0 482023.0 400211.0 427051.0 365100.0 441847.0 444089.0 391973.0 410383.0 420564.0 315868.0 True False 475149.263627809 399284.33601839107 391940.51524453226 391950.67193789623 415858.42816462525 425096.3486920212 412267.4440013814 429450.8923567971 373195.6535847455 370465.36293234647 1.2825740573068896 1.0777912754324281 1.05796804360387 1.0579954596442889 1.1225298496814353 1.1474658395247908 1.1128366785444088 1.1592200926898055 1.007369894531537 1.0 18.498979136909362 -14.522878745184693 0.11411341120332937 0.6346240714411953 1.172416373788933 0.2789831521206335 0.06702405303032029 259.5981294504166 1.9424043918553229 21.97704014034898 0.7744378238486499 3.000000000660689e-15 14.522878745184693 0.5377923023477378 SES(ph)PSLTQER ddPTM_PC-9_AZD4547_30min_R2 1 SESPSLTQER 10 0 H7BZJ7;Q9BXW9-3;Q9BXW9;Q9BXW9-1 H7BZJ7 FANCD2 Fanconi anemia group D2 protein 1 S(0.054)ES(0.824)PS(0.041)LT(0.081)QER 111.94 0.0015236 6685500.0 29177.0 40741.0 36877.0 36858.0 33215.0 35051.0 24719.0 39281.0 34761.0 31475.0 True False 38454.67908069904 53909.73151632221 36387.98688499624 28360.957550423424 28603.67058263363 32859.255429033554 26918.943112951823 33211.024037581745 36598.39549401201 30373.0698302444 1.2660781177412388 1.7749187624966658 1.1980345446926937 0.9337534107988852 0.9417444710890281 1.0818549330931806 0.8862766675677582 1.0934365285826793 1.204962017292327 1.0 14.890505109755507 -5.480799852323138 5.781336533166604 1.0204381452539921 1.5184181853836232 0.6567141513710223 0.14327015344745173 0.10706405346527334 9.250644009276328 0.0363412149687468 0.07457397302721092 3.305218292601218e-06 5.480799852323138 0.49798004012963104 SES(ph)PSLTQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SESPSLTQER 10 0 H7BZJ7;Q9BXW9-3;Q9BXW9;Q9BXW9-1 H7BZJ7 FANCD2 Fanconi anemia group D2 protein 1 S(0.273)ES(0.648)PS(0.005)LT(0.074)QER 91.31299999999999 0.008151 7889300.0 23549.0 29430.0 30384.0 31761.0 36065.0 23821.0 37494.0 20602.0 25334.0 20671.0 True False 27535.38058604897 32351.615903905822 31108.46979196168 29981.53414055133 28998.322144768747 22571.78482552615 33942.29688694724 20061.21932962337 25704.46182278076 24418.488668454036 1.12764475147971 1.3248819918040424 1.273971956837376 1.2278210395258462 1.1875559760678942 0.9243727215061585 1.3900244748069484 0.8215585985688061 1.0526639126518937 1.0 14.575686290030356 -7.070860955055066 0.6708357846902012 0.9781693266249117 1.2588655005676916 0.28881331229482876 0.1459242315478539 0.9050148814977181 0.8447115801555537 0.11764905693027963 0.09235337812569715 8.494523945766751e-08 7.070860955055066 0.2806961739427799 SES(ph)PVCSSR ddPTM_PC-9_AZD4547_30min_R2 1 SESPVCSSR 9 0 O00472;D6RC27 O00472 ELL2 RNA polymerase II elongation factor ELL2 1 SES(0.999)PVCSSR 96.756 0.0050028 19559000.0 14386.0 12459.0 18495.0 25328.0 25199.0 21922.0 15367.0 18580.0 18734.0 21479.0 True False 18960.448752611184 16486.12810097587 18249.74421558167 19489.02091369917 21700.553816401774 20551.21387450496 16734.6332301764 15708.887925925224 19724.240993780986 20727.026747698794 0.9147693484168566 0.7953928125656631 0.8804805647104131 0.9402709395288895 1.0469689686105639 0.9915176993143334 0.8073822373985383 0.7578939380521278 0.9516194114030783 1.0 14.339225558997473 -5.54761322210306 6.717155306361255 0.9199204301687502 0.8508166918324491 0.10313260165270266 0.08670943613782058 0.42073703964884224 69.38651618254154 0.026100684421632846 0.04665014827707743 2.8339147256125662e-06 5.54761322210306 -0.06910373833630112 SES(ph)PVCSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SESPVCSSR 9 0 O00472;D6RC27 O00472 ELL2 RNA polymerase II elongation factor ELL2 1 S(0.001)ES(0.999)PVCSSR 96.756 0.0080993 0.0 12011.0 14762.0 17163.0 15568.0 19589.0 17024.0 16536.0 14736.0 17436.0 12010.0 True False 14044.22507193656 16227.473801340742 17572.231011039974 14695.775432136996 15750.676070813111 16131.231470960785 14969.590369727413 14349.195614082615 17690.968514328775 14187.317928892311 0.9899140304268262 1.1438013782924874 1.2385872438408057 1.0358388742532665 1.1101940585074956 1.1370176908568261 1.055138853217775 1.0114100273217 1.2469565144727828 1.0 13.792314257431794 -7.26087209974534 24.99192642518351 1.0793271861723672 1.1133855163902093 0.027141007017590035 0.08832789077120672 235.19365462521432 10362038.470134817 0.03484909060395357 0.025229548220437447 5.484384569344252e-08 7.26087209974534 0.0340583302178421 SES(ph)PVCSSR ddPTM_PC-9_Lapatinib_30min_R1 2 SESPVCSSR 9 0 O00472;D6RC27 O00472 ELL2 RNA polymerase II elongation factor ELL2 1 S(0.021)ES(0.968)PVCS(0.009)S(0.002)R;S(0.12)ES(0.88)PVCSSR 84.31 0.013306 25970000.0 33353.0 31922.0 39451.0 28200.0 31201.0 29388.0 23917.0 26533.0 37080.0 20849.0 True False 32877.38010380889 31848.086570281852 36207.49106526389 30273.922072442303 29365.818523526174 28131.143746774007 25155.305233220235 27765.820043478685 32903.65993028969 24452.721870453748 1.3445284446446295 1.3024352355949351 1.4807141412348634 1.238059396120737 1.2009222809264815 1.1504299560518414 1.028732317264665 1.1354899544752994 1.3456031645314388 1.0 14.577707442291242 -6.127127829360151 2.3360559589296868 1.1402753900593754 1.3675345786563124 0.518452821747557 0.09902489764190602 0.252430279318815 2.702107478988791 0.031942843643982616 0.04480631779229767 7.462290825220559e-07 6.127127829360151 0.22725918859693706 SES(ph)PVPQNEK ddPTM_PC-9_AZD4547_30min_R2 1 SESPVPQNEK 10 0 Q9UIF8-4;Q9UIF8-2;Q9UIF8-5;Q9UIF8-3;Q9UIF8 Q9UIF8-4 BAZ2B Bromodomain adjacent to zinc finger domain protein 2B 1 S(0.044)ES(0.956)PVPQNEK 87.641 0.025144999999999997 0.0 32110.0 27710.0 38822.0 48033.0 40509.0 37611.0 33631.0 45069.0 34789.0 37559.0 True False 42320.312070509186 36666.71560141598 38307.1949141558 36959.73395245232 34885.0245862383 35259.178224341136 36624.093848120174 38104.62163259012 36627.87551684886 36244.07084206985 1.167647868665636 1.0116610730949005 1.0569230780139411 1.019745660290228 0.9625029356731625 0.9728261038330851 1.0104851082458766 1.0513339353801465 1.0105894472078316 1.0 15.145457383880473 SES(ph)QERPGSR ddPTM_PC-9_Lapatinib_30min_R1 2 SESQERPGSR 10 1 A0A3B3ISF0;Q659C4;H0Y9K3;D6R9W6;Q659C4-9;G3V0E9;A0A3B3IT29;A0A3B3ISF8;Q659C4-3 A0A3B3ISF0 LARP1B La-related protein 1B 1 SES(0.997)QERPGS(0.003)R;SES(0.936)QERPGS(0.064)R 95.094 0.029197000000000004 9453600.0 29006.0 31684.0 31069.0 27593.0 28105.0 23398.8 23365.0 19798.3 21598.4 18290.4 True False 28592.369120951054 31610.637644659153 28514.626749808227 29622.28126754964 26451.91915655598 22398.087869266878 24574.725374176985 20718.20129524759 19165.760750765072 21451.87126957394 1.3328613043424686 1.4735608491877257 1.329237267531606 1.3808716682709223 1.2330821318172747 1.0441088139958676 1.1455749041824763 0.9657992552208279 0.8934307179974853 1.0 14.388815880588185 -6.746528399403899 0.8807859963184003 0.95535789809026 1.4107646031953702 0.8784910842963072 0.06568132249432944 0.18399245439708867 0.31053371681755265 0.04057697801672112 0.03841425748347562 1.792551329937302e-07 6.746528399403899 0.4554067051051103 SES(ph)SDFEVVPK ddPTM_PC-9_AZD4547_30min_R2 1 SESSDFEVVPK 11 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3 E7EPN9 PRRC2C Protein PRRC2C 1 S(0.09)ES(0.455)S(0.455)DFEVVPK 118.9 0.0019224 0.0 8952.4 6992.5 10749.0 13009.0 12564.0 14003.0 10262.0 11098.0 12732.0 12136.0 True False 11799.076978512187 9252.68887920971 10606.461236728164 10009.976037046454 10819.705470426285 13127.39019636407 11175.298119871826 9383.059106669436 13404.987527106845 11711.122333910906 1.0075103514499715 0.7900770409013219 0.9056741902538181 0.8547409677432378 0.9238828834616969 1.1209335725536909 0.954246553083342 0.8012092128437346 1.1446373067328617 1.0 13.515591722508798 -6.532417867469253 24.955585679071092 0.9924084594100581 0.8842739053738984 0.22066735356149947 0.10156469792819627 328.0799442513123 858293.3556705039 0.03287932652391408 0.03291857447324429 2.9348244770911427e-07 6.532417867469253 -0.10813455403615968 SES(ph)SDFEVVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SESSDFEVVPK 11 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3 E7EPN9 PRRC2C Protein PRRC2C 1 S(0.045)ES(0.714)S(0.241)DFEVVPK;S(0.04)ES(0.48)S(0.48)DFEVVPK 164.65 6.6377e-13 2201900.0 29832.0 31673.0 32769.0 37941.0 40592.0 29824.0 37308.0 26704.0 27488.0 27025.0 True False 34881.96839114239 34817.28612043526 33550.33723712456 35815.28877638165 32638.288992110127 28259.976937848598 33773.91615347065 26003.048295226785 27889.95999781309 31924.418570217713 1.0926422454466806 1.090616138986359 1.0509302515042094 1.1218775589477368 1.0223612661988584 0.8852150862416122 1.0579336340671317 0.814519087889827 0.8736246812598689 1.0 14.962372724348173 -6.572114633490944 4.248745308806967 0.9234533688502626 1.085621463522641 0.5810513399240965 0.06525427879144566 0.15465733770338003 5.951944912185104 0.022029695640651326 0.022451265575863424 2.678461242640315e-07 6.572114633490944 0.16216809467237847 SES(ph)TENQSYAK ddPTM_PC-9_AZD4547_30min_R2 4 SESTENQSYAK 11 0 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 S(0.25)ES(0.743)T(0.008)ENQSYAK;S(0.001)ES(0.984)T(0.015)ENQSYAK;SES(0.993)T(0.007)ENQSYAK;S(0.023)ES(0.456)T(0.456)ENQS(0.065)YAK 201.0 4.5150000000000004e-26 22152100.0 45639.9 65469.0 74390.7 84557.0 86255.0 57900.2 83037.0 120702.0 85970.0 70161.0 True False 60152.43883110661 86630.57393392645 73404.23071198014 65063.69004262724 74279.98211967692 54279.69134096395 90427.13213601611 102050.27935602945 90514.19868876653 67704.68474534639 0.8884531263583075 1.2795358882441428 1.0841824459868785 0.9609924377810404 1.0971173176429638 0.8017124892483133 1.33561115417839 1.507285348715013 1.336897129485385 1.0 16.046968042375497 -7.301083065995695 22.571197707680337 1.3372226906466067 1.0344459162117123 0.3757560482383515 0.17029029458216813 165.83114203411162 94414.91100504022 0.06926700353960354 0.04670159665859281 4.9993890425565144e-08 7.301083065995695 -0.30277677443489437 SES(ph)TENQSYAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SESTENQSYAK 11 0 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 SES(0.993)T(0.007)ENQSYAK;SES(0.5)T(0.5)ENQSYAK;S(0.018)ES(0.904)T(0.078)ENQSYAK;S(0.37)ES(0.564)T(0.066)ENQSYAK 187.62 1.887e-35 19898300.0 46607.7 36619.200000000004 38268.9 45840.0 84346.0 50318.8 50082.8 68216.0 52116.0 44025.1 True False 54497.46306596433 40254.51216813822 39181.37571161146 43271.733415285176 67819.0067828272 47679.99354681519 45338.59461592795 66425.40228082634 52878.09790621466 52006.50212750016 1.047897105872594 0.7740284487783752 0.7533937894064405 0.8320446798978971 1.3040486094711925 0.9168083142742801 0.8717870412583211 1.2772518735825862 1.0167593616770778 1.0 15.666404387431449 SES(ph)TENQSYAK ddPTM_PC-9_Lapatinib_30min_R1 3 SESTENQSYAK 11 0 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 SES(0.95)T(0.05)ENQSYAK;SES(0.5)T(0.5)ENQSYAK;S(0.056)ES(0.886)T(0.056)ENQS(0.002)YAK 185.57 0.00036947 18518800.0 80667.0 78543.0 33572.0 26014.8 40221.0 28467.1 33789.0 27184.200000000004 57777.0 32530.0 True False 79516.67378748383 78361.13850916765 30811.839751667616 27928.01517482877 37855.27985752849 27249.62849305123 35538.42908915324 28447.277172801147 51269.545841217565 38152.7671564996 2.0841653099842743 2.0538782465695484 0.8075912194069677 0.7320049699218484 0.9922027333495671 0.7142241709828132 0.931477104750422 0.7456150442800831 1.3437962607250475 1.0 15.219500076666487 -5.258553863236815 24.925612161192333 0.8898663602311728 2.0690219311030984 0.8726344631201606 0.17725481346512875 68.23998052616814 589461.011804617 0.04364878264460307 0.10548546748512541 5.5137381417666305e-06 5.258553863236815 1.1791555708719255 SES(ph)VEGFLSPSR ddPTM_PC-9_Lapatinib_30min_R1 1 SESVEGFLSPSR 12 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 S(0.308)ES(0.692)VEGFLSPSR 67.118 0.037644 2647400.0 11170.0 9112.3 9368.9 10130.0 10954.0 11515.0 7747.9 7778.9 11301.0 12781.0 True False 11010.71375167288 9091.201029208043 8598.62520699985 10874.993992689377 10309.707256392609 11022.530292776055 8149.048351234142 8140.336092270619 10028.162375194277 14990.178820387993 0.7345285125416461 0.6064771566862959 0.5736172536717804 0.7254746006030566 0.6877641274279183 0.7353167980747782 0.5436258265412219 0.5430446287404543 0.6689821712837123 1.0 13.87172997309194 -8.573009994288078 21.616294352849636 1.0000000006374876 0.6416827921330649 0.6858448484258215 0.07193693180509016 4398.558678895477 1896628.530088277 0.0733651221106433 0.018942793059487387 2.6729448962798726e-09 8.573009994288078 -0.3583172085044227 SES(ph)VVSGLDSPAK ddPTM_PC-9_AZD4547_30min_R2 1 SESVVSGLDSPAK 13 0 H7BYJ3;O14578;O14578-4;O14578-2 H7BYJ3 CIT Citron Rho-interacting kinase 1 S(0.005)ES(0.481)VVS(0.392)GLDS(0.122)PAK 139.43 6.8409e-05 7279800.0 45767.0 45472.0 43340.0 57807.0 51259.0 56608.0 50384.0 55925.0 46320.0 55613.0 True False 60319.953987262335 60169.93474657476 42765.28328214705 44480.48925924701 44142.57264474537 53068.29281123878 54868.0783932588 47283.076278652756 48768.38063584582 53666.005797279795 1.1239881390673538 1.121192715065533 0.7968784456158413 0.8288391990130487 0.8225425385949415 0.988862353790613 1.0223991440786513 0.8810619604757212 0.9087387800028481 1.0 15.711720896114102 -5.242142690690907 24.21799444501696 0.903274020570446 1.1225905302266663 0.5775119179249051 0.07401172821098942 409.23112362720406 513595.7357153954 0.020452497354342198 0.05390884740554681 5.726078654913358e-06 5.242142690690907 0.2193165096562203 SES(ph)VVYADIR ddPTM_PC-9_Lapatinib_30min_R1 1 SESVVYADIR 10 0 O95297-4;O95297-2;O95297;O95297-5 O95297-4 MPZL1 Myelin protein zero-like protein 1 1 S(0.011)ES(0.989)VVYADIR 115.0 0.0023654 0.0 11392.0 9551.3 4968.9 4042.9 6515.1 7526.0 3231.9 5620.4 7944.1 3929.5 True False 11229.547990963067 9529.184551680122 4560.376222508676 4340.22835271904 6131.894627179427 7204.130523962882 3399.231968191848 5881.5443022789605 7049.351802918404 4608.708839270374 2.4365930638267157 2.0676473355146325 0.989512764106541 0.9417449667760227 1.3305016309405642 1.5631559239709754 0.7375670902069822 1.276180489460058 1.5295719579530695 1.0 12.170146911219437 -5.132377121705393 3.954176563380557 1.1781026205051954 2.363466902274886 0.7491256590147408 0.25340128095030745 0.11060922590811242 2.912524546697459 0.06741093168859552 0.21030566507997633 7.372637455604985e-06 5.132377121705393 1.1853642817696908 SESAPTLHPY(ph)SPLSPK ddPTM_PC-9_Lapatinib_30min_R1 1 SESAPTLHPYSPLSPK 16 0 Q8WUF5;K7EN03 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 SESAPT(0.002)LHPY(0.817)S(0.174)PLS(0.006)PK 78.69 0.016621 5688200.0 42392.0 27503.0 31531.0 26644.0 34516.0 39255.0 30714.0 34111.0 30918.0 34753.0 True False 41787.48230625932 27439.318493279272 28938.642893179785 28603.488641778466 32485.836741066938 37576.155157874404 32304.220635243815 35695.9215883278 27435.689259026363 40760.00974453832 1.0252078585888629 0.6731921475302403 0.7099763487435733 0.7017537243256233 0.7970026735682983 0.9218877864205972 0.7925469311148153 0.8757584164491254 0.6731031084383545 1.0 15.314866775959835 -6.5284650614950825 24.39612104170147 0.8431713702877877 0.7632696883011854 0.07401297387585459 0.12111540721312716 288.6835816625289 1260698.7941273176 0.038672728132012155 0.03879505182852136 2.961658217898994e-07 6.5284650614950825 -0.0799016819866023 SESAPTLHPYS(ph)PLSPK ddPTM_PC-9_AZD4547_30min_R2 1 SESAPTLHPYSPLSPK 16 0 Q8WUF5;K7EN03 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 S(0.001)ES(0.001)APT(0.003)LHPY(0.062)S(0.895)PLS(0.039)PK 70.414 0.011219 6965600.0 20477.0 18668.0 28636.0 34066.0 39902.0 38266.0 31728.0 32533.0 29681.0 32043.0 True False 26988.260051940735 24702.06592736317 28256.267929569993 26212.610014453418 34362.29605865564 35873.22097079681 34551.730534719674 27505.772383967982 31249.877065037534 30921.18432313013 0.8728080971902673 0.7988719212441406 0.9138158368802618 0.8477233517490294 1.1112865438647326 1.160150290361368 1.1174129093391085 0.8895445949459542 1.0106300178697079 1.0 14.916307957039411 -6.25233410816319 24.814516807034845 1.0517090435187295 0.8580246560340741 0.6017008191036763 0.07564454772429718 457.8851033081144 1247869.4933088191 0.024868791613171404 0.03165381332645704 5.593271385902115e-07 6.25233410816319 -0.19368438748465544 SESAPTLHPYS(ph)PLSPK ddPTM_PC-9_Lapatinib_30min_R1 1 SESAPTLHPYSPLSPK 16 0 Q8WUF5;K7EN03 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 SESAPTLHPYS(0.984)PLS(0.016)PK 166.3 5.0067e-05 16390000.0 55167.0 40246.0 53257.0 49319.0 79234.0 101150.0 73949.0 91435.0 95248.0 93649.0 True False 54380.30846361123 40152.81285970686 48878.415037965075 52946.08378336104 74573.61190003752 96824.05029216649 77777.71738476417 95683.40389987822 84520.1672340947 109836.10487055102 0.49510412380065694 0.36557025494512535 0.44501227620527384 0.48204626198062506 0.6789535370716884 0.8815320827908083 0.7081252332867253 0.8711470969645848 0.7695116950269422 1.0 16.744992843494217 -6.378712691215171 2.124224088469321 0.8313236996586807 0.4292867152034424 0.849774289261854 0.07893455236053415 0.11274782103626602 1.0009203318431923 0.02602704795876743 0.03094844342306766 4.181068750002156e-07 6.378712691215171 -0.4020369844552383 SESAPTLHPYSPLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 SESAPTLHPYSPLSPK 16 0 Q8WUF5;K7EN03 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 S(0.001)ESAPTLHPY(0.048)S(0.385)PLS(0.566)PK;SES(0.001)APTLHPYS(0.245)PLS(0.754)PK;SESAPTLHPYS(0.033)PLS(0.967)PK 183.73 8.137600000000001e-08 48268100.0 134464.0 138613.0 196129.0 275264.0 259070.0 228461.0 191949.0 237007.0 195532.0 226109.0 True False 177220.75497505264 183416.9415250478 193528.20131158788 211806.13758640623 223102.60237371334 214175.2975542052 209032.08914551465 200383.01402905065 205867.42233351033 218192.99273222344 0.8122201944062711 0.8406179283224992 0.886958828916631 0.9707284131087772 1.0225012250852399 0.9815865068455752 0.9580146755769032 0.9183751115003495 0.9435106955343904 1.0 17.73524524469228 -5.529693889251437 2.3814397899396877 0.9696411448219929 0.8245517126847804 0.8159641786249002 0.02795829974952825 0.13708554329542436 1.539930679425683 0.009149589163716056 0.021417438276687992 2.9532901080864095e-06 5.529693889251437 -0.14508943213721248 SESAPTLHPYSPLS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SESAPTLHPYSPLSPK 16 0 Q8WUF5;K7EN03 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 SESAPTLHPYS(0.008)PLS(0.992)PK;SESAPTLHPYS(0.044)PLS(0.956)PK 243.09 8.072100000000001e-47 28524000.0 57077.0 54333.0 68619.0 97442.0 139021.0 148562.0 156291.0 158496.0 142143.0 122421.0 True False 66739.0087778639 59726.82116571236 70255.13719900681 91982.64065122632 111780.83302059898 140771.14719154584 141485.98503114795 154335.64794039298 144221.5724668636 144614.95821589747 0.46149450652420343 0.413005832194381 0.48580823218938424 0.6360520501199073 0.7729548478223116 0.9734203773124689 0.9783634195013338 1.0672177335209223 0.9972797713743653 1.0 17.141857259283164 -6.311715679161066 1.1120679416800543 1.0267086953418376 0.4248728386015648 0.9846088276376852 0.030345400571474935 0.05042164956924979 0.13006841839768377 0.012701879647437065 0.018051990601569087 4.878477663055369e-07 6.311715679161066 -0.6018358567402728 down SESAPTLHPYSPLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 SESAPTLHPYSPLSPK 16 0 Q8WUF5;K7EN03 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 SESAPTLHPYS(0.306)PLS(0.694)PK 187.56 4.8058e-08 15022000.0 86795.0 54391.0 74896.0 70235.0 102140.0 136400.0 138360.0 147620.0 155060.0 134660.0 True False 85557.28738374631 54265.06098127308 68738.33998692068 75400.31619709182 96132.32601496633 130566.48996392988 145523.60379932067 154478.96411330524 137595.50994581226 157935.8015768289 0.5417219308702873 0.3435893599772278 0.4352296268524174 0.4774111724149691 0.6086797613662164 0.8267060961501813 0.9214098535380514 0.9781123885210912 0.8712116478471666 1.0 17.268978719116248 -6.685975279844053 1.5064246674690227 0.9475782948328083 0.43055851368292813 0.9445338699851203 0.05481949781636292 0.0784316158030743 0.36986436321800115 0.022894419328471596 0.022101862326685786 2.0607472082039423e-07 6.685975279844053 -0.5170197811498802 SESDLEDVGPTAEWNGDGS(ph)GSLRR ddPTM_PC-9_AZD4547_30min_R2 1 SESDLEDVGPTAEWNGDGSGSLRR 24 1 Q9H0B6;Q9H0B6-2;A8MZ87 Q9H0B6 KLC2 Kinesin light chain 2 1 SESDLEDVGPT(0.002)AEWNGDGS(0.499)GS(0.499)LRR 56.533 0.0032061999999999998 2763000.0 9286.3 8522.6 13333.0 14379.0 17272.0 14741.0 10941.0 12803.0 12015.0 12616.0 True False 12239.15023296074 11277.363781473394 13156.195708372565 11064.143703335463 14874.080936421733 13819.242939698832 11914.727804474533 10824.59053367173 12650.088370891348 12174.317680011542 1.005325354130987 0.9263240928885226 1.0806515859178805 0.9088101685978819 1.2217588966684194 1.1351143696856225 0.9786772546634611 0.8891332408258191 1.0390798649571098 1.0 13.571553297052276 -7.494607067068848 24.577350315240114 0.9652449654171031 1.0452204147165653 0.11438928441274165 0.0934292954802509 1215.356732704638 1056546.4443181385 0.040991156445737253 0.02756322283552725 3.2017906565527436e-08 7.494607067068848 0.07997544929946221 SESDLEDVGPTAEWNGDGS(ph)GSLRR ddPTM_PC-9_Lapatinib_30min_R1 2 SESDLEDVGPTAEWNGDGSGSLRR 24 1 Q9H0B6;Q9H0B6-2;A8MZ87 Q9H0B6 KLC2 Kinesin light chain 2 1 SESDLEDVGPT(0.105)AEWNGDGS(0.447)GS(0.447)LRR;SESDLEDVGPTAEWNGDGS(0.707)GS(0.293)LRR 71.289 0.00028937 3638800.0 15315.3 13379.3 17820.3 12018.0 14050.9 14103.099999999999 11982.099999999999 10762.1 12840.5 10162.8 True False 15096.901013517949 13348.321052871739 16355.183722347278 12901.84381087274 13224.45368713226 13499.943288931825 12602.474509134427 11262.14645497765 11394.267673540584 11919.426438920205 1.266579486091916 1.1198794775297074 1.372145195589538 1.082421530682439 1.1094874199609792 1.132600075860261 1.0573054478514068 0.9448564083757961 0.9559409365819119 1.0 13.541027194742636 -6.887826021287723 0.7065479837296849 0.9555142435324022 1.2352543820034232 0.6400893644269479 0.07591943190048979 0.45282021800546307 0.4858793777047486 0.05781482335025902 0.05174671307660043 1.2947144011864773e-07 6.887826021287723 0.27974013847102097 SESDLEDVGPTAEWNGDGSGS(ph)LRR ddPTM_PC-9_AZD4547_30min_R2 1 SESDLEDVGPTAEWNGDGSGSLRR 24 1 Q9H0B6;Q9H0B6-2;A8MZ87 Q9H0B6 KLC2 Kinesin light chain 2 1 SESDLEDVGPTAEWNGDGS(0.23)GS(0.77)LRR 93.236 3.6305000000000002e-06 2582200.0 6063.8 5768.9 8018.7 11477.0 9424.8 8542.0 6422.6 11127.0 6044.3 9083.1 True False 7991.962265124689 7633.584108011862 7912.366798674494 8831.154967882405 8116.329203889976 8007.867389655209 6994.198957775166 9407.577823023146 6363.789358316989 8765.103433680466 0.9117932635472465 0.8709063350786405 0.9027123134988598 1.0075357392758346 0.9259821364688597 0.9136078598781243 0.7979596602248311 1.073299122389581 0.7260369950528734 1.0 13.097555400447517 -5.598741484740706 0.00384131116920681 1.8171734660495673 2.1597739709505932e-07 0.01155361353825246 0.09558834826443771 308050.3615237728 247.13264617447095 57247.74881114735 59672.10184345641 2.5191760295942543e-06 5.598741484740706 -1.8171732500721702 SESDLEDVGPTAEWNGDGSGS(ph)LRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SESDLEDVGPTAEWNGDGSGSLRR 24 1 Q9H0B6;Q9H0B6-2;A8MZ87 Q9H0B6 KLC2 Kinesin light chain 2 1 SESDLEDVGPT(0.01)AEWNGDGS(0.44)GS(0.549)LRR 48.607 0.016662 2834900.0 1213.3 1350.2 3897.6 6011.4 3861.5 4888.5 4422.5 4227.6 4828.2 3503.1 True False 1418.687726232672 1484.2389328390639 3990.5335657303153 5674.600747221756 3104.8667950096883 4632.138454287585 4003.568783872733 4116.629979512461 4898.803290943002 4138.184299475656 0.3428285507758637 0.3586691228390021 0.9643199231691906 1.3712779172113667 0.7502968863429069 1.1193649482635457 0.9674699080898886 0.9947913581408334 1.1838050063559815 1.0 12.014782183610286 -5.283194999811721 4.678198081103852 1.0491032034315915 0.3403243345334045 0.7711245015272467 0.15159273340271165 0.07724218440098607 4.571222803692018 0.03836057897553247 0.09131927750773008 5.209607453021084e-06 5.283194999811721 -0.708778868898187 down SESELIDELS(ph)EDFDRSECK ddPTM_PC-9_Lapatinib_30min_R1 1 SESELIDELSEDFDRSECK 19 1 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;P20810-2;E9PCH5;P20810-3;H0Y7F0;H0Y9H6;E7EQ12;E7EQA0;H0YD33;A0A0A0MR45;D6RC54 P20810-6 CAST Calpastatin 1 S(0.005)ES(0.005)ELIDELS(0.974)EDFDRS(0.016)ECK 49.66 0.030307999999999998 1052300.0 3997.4 3294.1 3402.7 2893.9 4576.9 4180.0 2317.6 3189.4 4135.3 3353.5 True False 3940.3963429666205 3286.4727138389003 3122.943140801842 3106.7270597674024 4307.695740531617 4001.2311440559174 2437.593987896109 3337.5911674771405 3669.5389673604905 3933.14800674213 1.0018428841762541 0.8355832804169305 0.794006006244502 0.7898830795184691 1.0952284869899236 1.017310087796615 0.6197564860812841 0.8485801098143022 0.9329775948096116 1.0 11.941468761452759 -4.750249694992901 23.979671383527428 0.8738981164806217 1.0018433569795697 0.06894577582205985 0.1300324876370209 875.3022048008864 1875578.691097278 0.03381615933525796 0.4839425531952664 1.7772572928761096e-05 4.750249694992901 0.12794524049894807 SESELIDELSEDFDR ddPTM_PC-9_AZD4547_30min_R2 1 SESELIDELSEDFDR 15 0 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;P20810-2;E9PCH5;P20810-3;H0Y7F0;H0Y9H6;E7EQ12;E7EQA0;H0YD33;A0A0A0MR45;D6RC54 P20810-6 CAST Calpastatin 0 145.29 0.00051003 907540.0 2978.2 855.65 2853.0 3923.0 2620.5 3035.1 2530.2 4694.1 2551.2 2678.5 False True 3925.205649591732 1132.2221293522764 2815.1673558829157 3018.6129597458116 2256.6888081225784 2845.3147172023546 2755.3828983531157 3968.7347046870605 2686.0512236219724 2584.7265302719497 1.5186154525905473 0.4380432962991836 1.0891548188607483 1.1678655070051882 0.8730861008669815 1.1008184749444219 1.0660249222045206 1.53545632708366 1.03920132058975 1.0 11.335795932981405 -7.542583416446728 24.97544021414571 1.2325454576523456 1.0124059361479423 0.05110814376370476 0.28751342913205247 545.3913231730576 691268.5600670464 0.12792255072175665 0.07386785237798711 2.8669266621513815e-08 7.542583416446728 -0.2201395215044033 SESELIDELSEDFDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SESELIDELSEDFDR 15 0 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;P20810-2;E9PCH5;P20810-3;H0Y7F0;H0Y9H6;E7EQ12;E7EQA0;H0YD33;A0A0A0MR45;D6RC54 P20810-6 CAST Calpastatin 0 ; 133.32 0.00013312 0.0 1954.07 3150.69 1321.82 2977.1 967.25 2231.1 3153.5 1136.0500000000002 898.79 1619.51 False True 2284.855456358262 3463.4696810151904 1353.337201830265 2810.302738888425 777.7243059622224 2114.097188372921 2854.7776506371206 1106.229891244473 911.9331034063749 1913.114342965893 1.1943120204807312 1.81038299866896 0.7074000604334982 1.468967471401435 0.40652264660591053 1.1050553230892857 1.492214859573616 0.5782351145459971 0.47667464663539605 1.0 10.901707387880892 -5.267197696203393 24.974340565652376 0.9198644896388388 1.5023475149240038 0.27792534749279196 0.38488662315867106 550.6962543451457 2388427.980364382 0.10017757091738157 0.2180209820572958 5.405082209283886e-06 5.267197696203393 0.5824830252851649 SESELIDELSEDFDR ddPTM_PC-9_Lapatinib_30min_R1 3 SESELIDELSEDFDR 15 0 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;P20810-2;E9PCH5;P20810-3;H0Y7F0;H0Y9H6;E7EQ12;E7EQA0;H0YD33;A0A0A0MR45;D6RC54 P20810-6 CAST Calpastatin 0 ;; 300.55 4.6016e-104 2706490.0 5130.2 6991.599999999999 7461.2 5566.79 8922.0 6346.9 7968.6 7968.9 5072.8 6886.3099999999995 False True 5057.042407236542 6975.411379762625 6847.768937064891 5976.190306867061 8397.225501326899 6075.457882346533 8381.175117340748 8339.164185899715 4501.447845047831 8076.599508068698 0.6261350958636054 0.8636569601840525 0.8478529770138808 0.7399389187116084 1.0396981418897753 0.7522296823405715 1.0377108718796535 1.0325093100838676 0.5573444418719521 1.0 12.97953228735931 -4.240127186443993 1.429811631576215 0.8837347356240565 7.656038747366161e-31 0.1908074422975018 0.15177004047573084 8.310767553530512 5.280982217593109 0.041368204615535274 15.418579977409317 5.752714400464889e-05 4.240127186443993 -0.8837347356240565 SESGGLGVSMVEYVLS(ph)SSPADKLDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SESGGLGVSMVEYVLSSSPADKLDSR 26 1 Q8TB72-4;A0A0A0MR59;Q8TB72-3;Q8TB72;C9JW01;Q8TB72-2 Q8TB72-4 PUM2 Pumilio homolog 2 1 S(0.001)ES(0.001)GGLGVS(0.02)MVEY(0.023)VLS(0.318)S(0.318)S(0.318)PADKLDS(0.002)R 52.577 0.018304 2925000.0 6555.3 10136.0 5990.7 10617.0 11768.0 14772.0 8176.0 9818.6 8948.1 8068.5 True False 7664.982816923299 11142.235093509667 6133.5410078562645 10022.163910778423 9462.144877294833 13997.330315380219 7401.510090886027 9560.872153666627 9078.94903435796 9531.255179789145 0.8041944814547362 1.1690207515518602 0.6435187068396121 1.051505150342658 0.9927490869575228 1.468571562857881 0.7765514563686005 1.0031073529476249 0.9525449547935416 1.0 13.218450501149485 SESGLLAR ddPTM_PC-9_Lapatinib_30min_R1 1 SESGLLAR 8 0 E7ESL9 E7ESL9 AGAP3 0 94.006 0.031633999999999995 7467200.0 28238.0 25074.0 29779.0 31846.0 34143.0 32060.0 23676.0 24228.0 29812.0 21869.0 False True 27835.320941785023 25015.942693541972 27330.685570264224 34188.06107514175 32134.775867720706 30688.868535510228 24901.827432442285 25353.72132866247 26454.258625722665 25649.027511389177 1.0852388430487294 0.9753173948772097 1.0655642034821136 1.3329184141566734 1.2528652734865524 1.1964924799539929 0.9708682881401602 0.9884866518781041 1.0313942161735346 1.0 14.646616506313809 -7.265546757490941 24.94708510299885 0.9967278371950721 1.152357051737256 0.38653575093357195 0.09485896975265015 436.7183262868759 2652489.72272047 0.045115322060947156 0.03166419126797009 5.4256683375620085e-08 7.265546757490941 0.15562921454218404 SESLIDASEDS(ph)QLEAAIR ddPTM_PC-9_AZD4547_30min_R2 5 SESLIDASEDSQLEAAIR 18 0 C9JAT7;O94888 C9JAT7 UBXN7 UBX domain-containing protein 7 1 SESLIDAS(0.089)EDS(0.911)QLEAAIR;SESLIDASEDS(1)QLEAAIR;SESLIDASEDS(1)QLEAAIR;SESLIDAS(0.001)EDS(0.999)QLEAAIR;S(0.118)ES(0.004)LIDASEDS(0.878)QLEAAIR 219.95 9.2961e-69 18219500.0 40287.1 41269.17 48506.25 60898.2 43983.7 46305.40000000001 43386.5 55959.6 46140.90000000001 42381.2 True False 53097.55977626315 54608.622139894884 47863.02543157928 46859.06085781091 37877.322468926155 43409.916017904485 47247.8144492125 47312.32964368165 48579.813775485716 40897.447087833316 1.2983098837985727 1.3352574800724062 1.1703181699529155 1.145769826590255 0.9261537129097326 1.0614333927659414 1.1552753976975831 1.1568528847796153 1.1878446513092462 1.0 15.31972316920368 -5.469405672992353 2.293652425429625 1.0909944616313232 1.3206259993179617 0.5802230885520627 0.07619693089717886 0.2379496839925392 2.4316794461765086 0.023474760640819926 0.06036129143379057 3.3930817790475057e-06 5.469405672992353 0.22963153768663846 SESLIDASEDS(ph)QLEAAIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 SESLIDASEDSQLEAAIR 18 0 C9JAT7;O94888 C9JAT7 UBXN7 UBX domain-containing protein 7 1 SESLIDAS(0.011)EDS(0.989)QLEAAIR;SESLIDASEDS(1)QLEAAIR;SESLIDASEDS(1)QLEAAIR;SESLIDAS(0.04)EDS(0.96)QLEAAIR;SESLIDAS(0.001)EDS(0.999)QLEAAIR;SESLIDASEDS(1)QLEAAIR;SESLIDAS(0.001)EDS(0.999)QLEAAIR 295.52 5.906899999999999e-121 20057000.0 63716.73 62188.11 66565.27 63979.73 66932.15 47593.240000000005 53215.200000000004 49455.09999999999 47888.71 32566.54 True False 74502.71392621865 68361.73457389906 68152.43848699231 60395.153153183324 53817.27568395896 45097.36671128936 48174.27101131585 48156.95602700984 48588.99178721157 38470.5959054112 1.9366145018756842 1.7769866300481043 1.771546212971609 1.5699042796654017 1.3989197312222845 1.1722554759009087 1.2522361527688148 1.2517860691686393 1.2630163542742818 1.0 15.231468556548759 -6.072426105652956 1.0071340746816924 1.1890765205750289 1.8952881469967715 0.9264515889807704 0.0793437363177418 0.13841944657446165 0.2888483711136028 0.03331488718242674 0.0648331139835871 8.463965692582793e-07 6.072426105652956 0.7062116264217426 SESLIDASEDS(ph)QLEAAIR ddPTM_PC-9_Lapatinib_30min_R1 12 SESLIDASEDSQLEAAIR 18 0 C9JAT7;O94888 C9JAT7 UBXN7 UBX domain-containing protein 7 1 SESLIDAS(0.285)EDS(0.715)QLEAAIR;SESLIDASEDS(1)QLEAAIR;SESLIDAS(0.015)EDS(0.985)QLEAAIR;SESLIDASEDS(1)QLEAAIR;SESLIDASEDS(1)QLEAAIR;SESLIDAS(0.001)EDS(0.999)QLEAAIR;SESLIDASEDS(1)QLEAAIR;SESLIDASEDS(1)QLEAAIR;SESLIDAS(0.001)EDS(0.999)QLEAAIR;SESLIDAS(0.001)EDS(0.999)QLEAAIR;SESLIDASEDS(1)QLEAAIR;SESLIDASEDS(1)QLEAAIR 257.88 1.4080999999999998e-151 15612620.0 102999.7 101930.46999999999 120191.50000000001 89969.99999999999 70638.40000000001 71122.40000000001 69442.81 66572.62000000001 74427.3 43513.420000000006 True False 101530.90539016825 101694.45625930458 110309.8188226072 96586.69393112192 66483.58819243782 68080.6607464121 73038.21891552114 69665.82696049778 66044.51371978561 51034.65666901243 1.9894501504860025 1.9926548525416476 2.161468813987062 1.892570661492626 1.302714518559812 1.3340084011528146 1.4311494126278501 1.3650689846376092 1.2941110615893878 1.0 15.639189666319567 -6.19178931343032 3.707766309026994 1.312423525321945 2.0401849315482257 0.9007078197536691 0.11779627069197787 0.06846777957603593 1.8507803361990611 0.034906894629441576 0.045368595606814534 6.429995760344249e-07 6.19178931343032 0.7277614062262807 SESLS(ph)NCSIGK ddPTM_PC-9_AZD4547_30min_R2 1 SESLSNCSIGK 11 0 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 S(0.007)ES(0.147)LS(0.843)NCS(0.003)IGK 179.59 0.0019111 35921000.0 38226.0 34719.0 51489.0 55178.0 56549.0 63234.0 50493.0 68174.0 54474.0 53699.0 True False 50381.07284980641 45941.23778295061 50806.22221768507 42457.56459160191 48698.14745679208 59279.96798378101 54986.77918209782 57639.27478267092 57353.38442912485 51819.01435470352 0.9722506974938904 0.8865710464595242 0.9804552026002301 0.8193433456873175 0.9397737117007097 1.143981002378913 1.0611313215205291 1.112319010703821 1.1068019170827588 1.0 15.661193953942313 -6.677482935850812 6.166741487016157 1.0899699514339185 0.9134194356062523 0.691792503842594 0.05516020164169898 0.10997819545241466 6.4273333510357284 0.017389398161014022 0.017296269261061915 2.1014403364944795e-07 6.677482935850812 -0.17655051582766623 SESPFRET(ph)EPLVSPHQDK ddPTM_PC-9_AZD4547_30min_R2 1 SESPFRETEPLVSPHQDK 18 1 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 SES(0.001)PFRET(0.999)EPLVSPHQDK 82.449 0.0019222999999999998 6137800.0 19758.0 16137.0 29031.0 43134.0 40443.0 30574.0 27199.0 33524.0 24617.0 29896.0 True False 26040.633008069777 21352.969673765772 28646.029971481577 33190.12271365682 34828.1875469954 28662.20294677103 29619.658308555223 28343.636104882524 25918.204363398436 28849.350139634196 0.9026419271848446 0.740154269348007 0.9929523484179531 1.1504634438215344 1.2072433998832883 0.9935129494440135 1.026701057916128 0.982470522479572 0.898398204394599 1.0 14.81625120064251 -5.407012889051378 5.465065059635846 1.0431573604175781 0.8241833487888739 0.4688604272577196 0.0901202727046425 0.19366113503027985 7.895610951164157 0.025627884458046955 0.05447514451084034 3.9173025111098365e-06 5.407012889051378 -0.21897401162870422 SESPFRET(ph)EPLVSPHQDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SESPFRETEPLVSPHQDK 18 1 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 S(0.006)ES(0.139)PFRET(0.855)EPLVSPHQDK 99.39200000000001 0.00047001 5926200.0 11382.0 14498.0 22718.0 18897.0 25291.0 26332.0 23658.0 21459.0 23517.0 16573.0 True False 13308.747795252852 15937.265626055962 23259.683278494787 17838.26235490061 20335.4101029626 24951.10356516327 21416.94297091262 20895.72398768992 23860.891635207026 19577.55370820419 0.6797962602281445 0.8140580719938098 1.1880791453912631 0.9111589027297772 1.0387104745594862 1.274475041011239 1.0939539888447665 1.0673306940761111 1.218788209744911 1.0 14.25691288537307 -5.103772405657619 3.872734393668898 1.0982559668926468 0.7018259277953026 0.6611959104721269 0.10252275199036494 0.13261338329045524 3.4502702360194832 0.026962269674036154 0.08750184017771745 7.874583533376741e-06 5.103772405657619 -0.3964300390973442 SESPKEPEQLR ddPTM_PC-9_AZD4547_30min_R2 1 SESPKEPEQLR 11 1 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8W646 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 0 84.198 0.015736 14628000.0 41547.0 41739.0 53088.0 72254.0 52906.0 53968.0 50977.0 57212.0 49476.0 48059.0 False True 54758.08176871524 55230.3154993685 52384.01843291703 55596.956613171984 45560.91512403479 50593.372428577844 55513.85424446559 48371.20000097062 52091.20035274413 46376.46903802112 1.1807298594427826 1.1909124744725321 1.129538740648209 1.1988182318837506 0.9824144888366187 1.090927650983941 1.1970263238228274 1.0430117040888591 1.1232248041574244 1.0 15.50110536134328 -1.5228787452811987 0.08384066198897594 0.9320558515865829 1.619480299385977 0.3482139066284121 0.06288065621693424 215.90961367770117 1.3179509247355448 1.5442118015852353 17.130675102578888 0.029999999999940515 1.5228787452811987 0.687424447799394 SESPKEPEQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SESPKEPEQLR 11 1 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8W646 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 0 69.672 0.044246 9480300.0 22808.0 30162.0 34260.0 27656.0 29714.0 28949.0 36253.0 30112.0 37370.0 26971.0 False True 26668.943921466067 33156.284026286354 35076.88833177354 26106.523981961767 23891.755003733768 27430.863478198073 32818.853391009194 29321.591906301255 37916.46555290583 31860.62879768148 0.8370501439509187 1.0406663420496949 1.1009477733322737 0.8193976379983298 0.7498833483623019 0.8609642845527969 1.0300755079070332 0.9203080106327032 1.190072731887358 1.0 14.959487119555952 -8.23924910944367 23.51830498244371 1.09503633223965 0.9226604417332874 0.2784955010886332 0.11268087487844715 459.103866025793 486582.6857331137 0.08182726871696684 0.030855848690451795 5.764357274972477e-09 8.23924910944367 -0.17237589050636248 SESPKEPEQLR ddPTM_PC-9_Lapatinib_30min_R1 1 SESPKEPEQLR 11 1 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8W646 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 0 84.68700000000001 0.015390000000000001 26690000.0 50511.0 49714.0 58130.0 43602.0 52692.0 48125.0 56553.0 47372.0 47705.0 40079.0 False True 49790.70387741707 49598.890287419075 53350.775788289015 46808.63653200813 49592.760156457836 46066.80593485431 59481.03762404582 49573.07605998837 42331.960544079564 47006.60174808939 1.059227896205895 1.0551473291607396 1.1349634690505463 0.9957885656754732 1.0550169191601595 0.9800071526490791 1.2653762538038278 1.0545981674159906 0.9005535173748264 1.0 15.52057576698626 -8.145463835248894 6.30267173265172 0.9522284537874733 1.07724448230857 0.29175383021688905 0.07824180514734573 0.28835233412236877 13.577240283300739 0.05402710632925965 0.019967143395097506 7.153789629302454e-09 8.145463835248894 0.12501602852109672 SESQESLVT(ph)SPSKPK ddPTM_PC-9_AZD4547_30min_R2 1 SESQESLVTSPSKPK 15 1 E7EWD6;Q76L83;A0A5F9ZHN2;Q76L83-2 E7EWD6 ASXL2 Putative Polycomb group protein ASXL2 1 SESQESLVT(0.491)S(0.491)PS(0.018)KPK 71.263 0.015884 30004000.0 47994.0 47421.0 56155.0 58711.0 63421.0 75777.0 60231.0 61362.0 63674.0 64527.0 True False 63255.09366278476 62748.91088180249 55410.34800897483 45176.08602590777 54616.08887614653 71038.65221094606 65591.44231709212 51879.91285848354 67039.67764695252 62267.929370490194 1.0158534947648734 1.0077243858303122 0.8898697703481804 0.7255112942187775 0.877114261358914 1.1408545768122564 1.0533743932101425 0.8331722827942677 1.076632518933956 1.0 15.926201684835075 -6.70125487656694 24.99988608796528 1.012418445836944 0.8984066759688422 0.2354382007072744 0.10523470271040863 125.17615272290075 51995.658317528665 0.03768495879218858 0.03768494155933991 1.9895054053530726e-07 6.70125487656694 -0.11401176986810191 SESS(ph)DFEVVPK ddPTM_PC-9_AZD4547_30min_R2 1 SESSDFEVVPK 11 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3 E7EPN9 PRRC2C Protein PRRC2C 1 S(0.003)ES(0.109)S(0.889)DFEVVPK 144.1 0.00016813 5129200.0 46493.0 41629.0 58905.0 58433.0 58967.0 55561.0 60416.0 55618.0 50165.0 54703.0 True False 61276.806885524275 55084.7601505357 58123.8812121567 44962.17463085059 50780.44989451023 52086.76188675171 65792.90695869963 47023.516074494575 52816.61948612273 52787.86462029733 1.160812382283084 1.0435118098972163 1.1010841531522688 0.8517521016290985 0.961972041486686 0.9867184865576842 1.2463642435993094 0.8908016342910313 1.0005447249293418 1.0 15.687918686701824 -4.784794538853697 1.4648586490987727 1.000344623458846 1.2154336722167087 0.17934539049212928 0.10259473851992999 2.191243246630443 4.3514636420689525 0.030312288799516966 0.694485057398957 1.6413661063474926e-05 4.784794538853697 0.21508904875786272 SESS(ph)DFEVVPK ddPTM_PC-9_Lapatinib_30min_R1 2 SESSDFEVVPK 11 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3 E7EPN9 PRRC2C Protein PRRC2C 1 S(0.004)ES(0.093)S(0.904)DFEVVPK;SES(0.114)S(0.885)DFEVVPK 164.9 3.7213e-13 5426900.0 83515.0 74081.0 66321.0 66471.0 73531.0 76363.0 76737.0 71392.0 74241.0 54329.0 True False 82324.06078522486 73909.46999602312 60868.343386463435 71359.49908075557 69206.05114750816 73097.13250084735 80710.06638297538 74709.13294930955 65879.19678761152 63719.69526115792 1.2919719789590354 1.1599156225261589 0.9552516398107666 1.1198970551928347 1.0861014143878776 1.1471670132955847 1.266642378815242 1.1724653208574045 1.0338906442914204 1.0 15.959451746753734 -8.37590927791662 4.579132897331395 1.0034768021313905 1.1442083400390521 0.2675496779648331 0.08817877511245296 0.33682411556152986 10.491550469410555 0.0905893384541156 0.023756912649765507 4.208145253870819e-09 8.37590927791662 0.14073153790766169 SESSTSAFS(ph)TPTR ddPTM_PC-9_Lapatinib_30min_R1 2 SESSTSAFSTPTR 13 0 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 SESSTSAFS(0.5)T(0.5)PTR;SESST(0.002)S(0.004)AFS(0.484)T(0.484)PT(0.026)R 145.14 9.601399999999999e-05 27500000.0 113322.0 98901.0 115605.0 101228.0 94459.0 103572.0 83803.0 86435.0 109092.0 78262.0 True False 111706.00749929032 98672.0008109592 106100.40314820489 108672.64480670863 88903.10733353932 99142.46699812438 88141.90928877187 90451.08564648117 96804.910170312 91789.48242244004 1.2169804704333014 1.0749815578743973 1.1559102453579826 1.1839335176395016 0.9685544028278007 1.080107049104427 0.9602615350102853 0.9854188438518565 1.0546405493909379 1.0 16.48604123333797 -6.259490096329596 24.999632972703832 1.0086367268019159 1.1518792306366241 0.7003074928538695 0.047937385776801046 101.77918310612402 1305320.0248514237 0.014057087169696047 0.017219947636648303 5.501864668439696e-07 6.259490096329596 0.14324250383470827 SESSTSAFST(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 2 SESSTSAFSTPTR 13 0 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 SESSTSAFS(0.007)T(0.947)PT(0.045)R;SESSTSAFS(0.036)T(0.964)PTR 128.57 0.00025273 33175000.0 112821.0 113718.0 176026.0 234800.0 220170.0 164902.0 140515.0 197724.0 147590.0 176283.0 True False 148695.73117741884 150475.1196233065 173691.78022665487 180670.48762383798 189603.19591083677 154590.65187180048 153020.5627863755 167170.29904551315 155391.30608904315 170111.38582636946 0.8741080466488628 0.8845681839127132 1.021047353079234 1.0620716934740986 1.1145826306086435 0.9087613455197479 0.8995315748151135 0.9827108175824384 0.9134679923638332 1.0 17.37612018054986 -5.246926009474452 21.713959864901415 0.9883635022112301 0.8793379311449632 0.3068414319156504 0.06518544505576958 190.86690979920598 285553.0429203324 0.018512185337684235 0.04826222306178189 5.663357671503633e-06 5.246926009474452 -0.10902557106626698 SESSTSAFST(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SESSTSAFSTPTR 13 0 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 SESSTSAFS(0.005)T(0.991)PT(0.004)R;SESSTS(0.002)AFS(0.34)T(0.655)PT(0.002)R;S(0.027)ESST(0.001)S(0.002)AFS(0.046)T(0.902)PT(0.023)R 114.87 0.000729 32684200.0 186125.0 191901.0 203669.0 255050.0 244012.0 231341.0 247267.0 206354.0 232398.0 194630.0 True False 217632.2863636822 210951.6630504736 208525.2413789833 240760.37538325635 196199.60025479863 219209.07070744495 223844.0797019467 200937.4261501358 235796.38109617878 229914.87830976828 0.9465776550157075 0.9175207128885969 0.9069671476329325 1.0471717931141271 0.8533575630127578 0.9534357772710159 0.973595451271134 0.8739644325210192 1.0255812187086313 1.0 17.81074030356026 -8.287486103895304 24.949526032874445 1.0127906409445726 0.9356606642033009 0.27284190819180953 0.051350481135627894 1119.4645631099947 1072297.1031173537 0.0468657919019272 0.012115630030572961 5.158386700793595e-09 8.287486103895304 -0.07712997674127176 SEST(ph)ENQSYAK ddPTM_PC-9_Lapatinib_30min_R1 1 SESTENQSYAK 11 0 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 S(0.142)ES(0.251)T(0.607)ENQSYAK 120.55 0.0020913 8949400.0 27427.0 28627.0 15355.0 6696.9 17289.0 12759.0 12264.0 11809.0 16576.0 9588.7 True False 27035.88595050421 28560.715940337628 14092.571172014068 7189.412366203506 16272.095011481806 12213.327312681691 12898.969911787133 12357.689250874 14709.036326981728 11246.09401886037 2.404024535555493 2.539612054855633 1.2531080700890447 0.6392808342297719 1.4469108104727322 1.0860061539765906 1.1469733304874377 1.0988427831164684 1.3079240047534546 1.0 13.457136392716032 -5.289867359608735 5.4573363319971175 1.1139244311297594 2.4800823956910345 0.8773116737546118 0.20214016567126342 0.04903089899798129 4.50230160096636 0.05124708520057393 0.11597621169072592 5.130180438768983e-06 5.289867359608735 1.3661579645612751 up SESVEGFLS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 1 SESVEGFLSPSR 12 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 SESVEGFLS(0.5)PS(0.5)R 122.52 0.00039703 9215500.0 10540.0 10747.0 17721.0 24468.0 18622.0 17679.0 15043.0 15868.0 15133.0 16522.0 True False 13891.500754380784 14220.757580960571 17486.0079613043 18827.280626831624 16036.656739117974 16573.529335251038 16381.797857847578 13415.965210364991 15932.899485368187 15943.569808905404 0.8712917446268262 0.8919431313944169 1.096743588223094 1.180869833574881 1.0058385249557207 1.0395118241332482 1.0274861937567707 0.841465579613883 0.9993307443900514 1.0 13.960687068413334 SESVEGFLS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SESVEGFLSPSR 12 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 SESVEGFLS(0.507)PS(0.492)R;SESVEGFLS(0.977)PS(0.023)R 106.55 0.0016579000000000001 12925100.0 19563.5 17258.1 21959.8 27845.4 30391.0 25384.0 29447.0 24942.0 27366.0 19498.8 True False 22875.214153262088 18971.370113190518 22483.40491500526 26285.312514004832 24436.10171361891 24052.818354021885 26657.5669821821 24287.298928233457 27766.175978614443 23033.77808758414 0.9931160257896413 0.8236325817264265 0.9761058229142379 1.1411637471741276 1.0608811815718004 1.0442411254707291 1.1573249894489208 1.0544209827794164 1.2054546967082747 1.0 14.491463446398006 -5.583422373163816 4.848120845457408 1.095386456218788 0.905763904796424 0.5558842705817072 0.06874616239921605 0.12622629018717518 5.96539984504075 0.017605231719587326 0.03182838465128926 2.6096221314413557e-06 5.583422373163816 -0.18962255142236406 SESVEGFLS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 1 SESVEGFLSPSR 12 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 SESVEGFLS(0.996)PS(0.004)R 109.6 0.0012929999999999999 9319200.0 6539.6 7615.3 8738.7 6409.5 7206.2 6118.5 5036.0 4699.3 8063.9 5629.3 True False 6446.344104784234 7597.66724073264 8020.237818357499 6880.87601146521 6782.345483934302 5856.826017920128 5296.739438662754 4917.6466336380845 7155.658665368479 6602.317004429245 0.9763760359370243 1.150757716667596 1.214761092655355 1.0421910984960416 1.0272674697964794 0.8870864597975233 0.8022546380474267 0.7448364915436537 1.0838102230729028 1.0 12.688756694615815 -6.541729479910579 2.1338309373271014 0.8801761804435824 1.1106461952125426 0.4108309594667079 0.1073005977500508 0.2792195015417159 2.564535275192556 0.03950842398687326 0.042086088480158906 2.8725693354486425e-07 6.541729479910579 0.23047001476896023 SESVVSGLDS(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 3 SESVVSGLDSPAK 13 0 H7BYJ3;O14578;O14578-4;O14578-2 H7BYJ3 CIT Citron Rho-interacting kinase 1 SESVVS(0.01)GLDS(0.989)PAK;S(0.002)ESVVS(0.013)GLDS(0.985)PAK;SES(0.001)VVS(0.002)GLDS(0.998)PAK 157.68 7.8822e-05 84838100.0 462226.0 443970.0 452498.0 519093.0 498706.0 509674.0 462958.0 481291.0 477296.0 483243.0 True False 609204.2531019355 587474.6201934547 446497.58086305886 399424.12875690317 429469.2801921682 477804.0042092158 504160.3651315169 406918.53491692594 502524.89214090345 466324.8096577224 1.3063946856035498 1.2597970513828225 0.9574819345142358 0.8565363036336762 0.9209659689935739 1.024616306732466 1.0811356262635166 0.8726075183853073 1.0776284721152871 1.0 18.830975661176623 -5.236386436550533 5.5003238523086955 0.9684622108896891 1.2892093228085526 0.7406627548003235 0.0732146587126503 0.08704744713579819 8.415628851323957 0.01944056252968181 0.050544792555733846 5.802478814184809e-06 5.236386436550533 0.3207471119188635 SESVVSGLDS(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SESVVSGLDSPAK 13 0 H7BYJ3;O14578;O14578-4;O14578-2 H7BYJ3 CIT Citron Rho-interacting kinase 1 SESVVS(0.003)GLDS(0.996)PAK;SESVVSGLDS(1)PAK;SESVVSGLDS(1)PAK;SESVVS(0.019)GLDS(0.981)PAK;SESVVS(0.027)GLDS(0.973)PAK 172.82 8.049899999999998e-19 49043700.0 335235.0 310123.0 309606.0 378253.0 374955.0 324980.0 402817.0 334870.0 283137.0 278499.0 True False 391983.66430694016 340909.96190849406 316988.1812272929 357060.7107227716 301485.2593869893 307937.4767054067 364659.2576174709 326080.0173240943 287277.34298242163 328988.66410312924 1.1914807623403816 1.036236196277048 0.9635231113249711 1.0853283097038338 0.9164001446945954 0.9360124232392287 1.1084249927321506 0.9911588237030466 0.8732135004273819 1.0 18.327678348598077 -4.7660788099663485 2.6779061484136553 0.9877379149446075 1.2369028420215107 0.4581246834575661 0.06768553133404728 0.46453911328713204 4.279481759689243 0.01763031282867245 0.26703854168348057 1.713646309629984e-05 4.7660788099663485 0.2491649270769032 SESVVSGLDS(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 4 SESVVSGLDSPAK 13 0 H7BYJ3;O14578;O14578-4;O14578-2 H7BYJ3 CIT Citron Rho-interacting kinase 1 SESVVSGLDS(1)PAK;S(0.003)ES(0.025)VVS(0.003)GLDS(0.969)PAK;SESVVS(0.003)GLDS(0.997)PAK;SESVVS(0.008)GLDS(0.992)PAK 184.02 5.4214e-05 98459000.0 491269.0 597061.0 520412.0 582903.0 527385.0 514094.0 477845.0 476915.0 489910.0 429654.0 True False 484263.4139722996 595678.5419378172 477625.73420841456 625771.631127406 496365.25117880385 492107.398031647 502585.4759864588 499074.2119638058 434731.17681899184 503919.1214220319 0.9609943210841753 1.1820915631398257 0.9478222077792586 1.2418096566002756 0.9850097566809701 0.9765602794411674 0.9973534534037732 0.990385541543742 0.862700299191276 1.0 18.94283267545046 -6.491474091948189 24.738063258601397 0.968350385451212 1.0846804150946865 0.2796275864645906 0.09042384436805538 744.138261069135 586172.8097317935 0.026163234748376403 0.029633799944968963 3.2249717008576043e-07 6.491474091948189 0.1163300296434745 SESVVY(ph)ADIR ddPTM_PC-9_AZD4547_30min_R2 1 SESVVYADIR 10 0 O95297-4;O95297-2;O95297;O95297-5 O95297-4 MPZL1 Myelin protein zero-like protein 1 1 SESVVY(1)ADIR 104.2 0.0038260999999999994 3596800.0 18777.0 28744.0 36207.0 29890.0 28617.0 26280.0 27032.0 33380.0 24791.0 20927.0 True False 24747.695414137383 38034.93588044392 35726.871522766465 22999.322295896585 24644.023515376386 24636.707445579344 29437.795632077094 28221.887996091704 26101.401648170402 20194.35209968306 1.2254760782608016 1.8834442270143867 1.769151659157571 1.1388987466578613 1.2203423706652694 1.219980087698184 1.457724193713504 1.3975139116512993 1.2925099809753269 1.0 14.301664239996562 -1.5228822153479589 0.04500623089641759 0.1873241636216404 3.446930617643688 0.2692404409335043 0.22497215862920714 847.686308727993 2.903992600215312 53.49219926975927 200.2821487670293 0.029999760297178334 1.5228822153479589 3.2596064540220473 SESVVY(ph)ADIR ddPTM_PC-9_Lapatinib_30min_R1 1 SESVVYADIR 10 0 O95297-4;O95297-2;O95297;O95297-5 O95297-4 MPZL1 Myelin protein zero-like protein 1 1 SESVVY(1)ADIR 117.31 0.0014027 3731300.0 39480.0 46736.0 25075.0 8536.4 24615.0 14012.0 13800.0 11740.0 23735.0 8713.8 True False 38917.00796025468 46627.7856634513 23013.43029229911 9164.195332595618 23167.194094951978 13412.739423567346 14514.496476081411 12285.483258977107 21061.714359369646 10219.968719591348 3.807938069874132 4.562419606438457 2.251810247538538 0.8966950471216368 2.2668556754524323 1.3124051346512988 1.4202094814886852 1.2021057594262725 2.0608394151926337 1.0 13.3191031601538 -5.3982590456375315 3.9266800724898916 1.4893900675404765 4.173623360832992 0.8519316221971666 0.4483297056663013 0.07310932547306317 1.9275977988896098 0.11302565122676111 0.2530713544996291 3.99706263999532e-06 5.3982590456375315 2.6842332932925155 SET(ph)PPHWR ddPTM_PC-9_AZD4547_30min_R2 1 SETPPHWR 8 0 Q13427;E9PG73;C9JM79 Q13427 PPIG Peptidyl-prolyl cis-trans isomerase G 1 SET(1)PPHWR 95.523 0.013422 12332000.0 39286.0 37062.0 47885.0 59657.0 57822.0 51161.0 44463.0 53123.0 45184.0 45994.0 True False 51778.13080043673 49041.56671308835 47250.01361249684 45904.00034146208 49794.41338037155 47961.89458231679 48420.1208637557 44914.06099509829 47572.33399503578 44383.764059484034 1.1666007130680178 1.104943840440433 1.0645787849171917 1.0342520810073836 1.1219060491047144 1.0806180052245518 1.0909421922589093 1.0119479937506775 1.0718409085646354 1.0 15.437744403093316 -1.5228787452803378 0.09759495628953276 0.9647187926747163 1.4287575538457402 0.4962610559987104 0.034150633261138506 128.8445839821119 0.897788078480231 0.5027515122262406 8.000042330912617 0.02999999999999998 1.5228787452803378 0.46403876117102394 SET(ph)PPHWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SETPPHWR 8 0 Q13427;E9PG73;C9JM79 Q13427 PPIG Peptidyl-prolyl cis-trans isomerase G 1 SET(1)PPHWR;S(0.001)ET(0.999)PPHWR 96.34200000000001 0.012896000000000001 22369000.0 156869.0 182725.0 166696.0 185557.0 203318.0 173766.0 180537.0 162038.0 139842.0 129201.0 True False 183423.82339602124 200864.73041254494 170670.66483810026 175160.84287391108 163479.2974304755 164653.4050624398 163435.2283853098 157784.6741934527 141886.92469492817 152624.11854544652 1.2018010334415368 1.316074630450586 1.1182417724317935 1.14766161825042 1.0711236139378368 1.0788164192634557 1.0708348715975982 1.0338121896931352 0.9296494292458688 1.0 17.219623437634517 -5.721264140978137 0.4058666021194216 0.9770021937705199 1.3484112003871522 0.7739100616696054 0.048743350021410996 1.2144690750050238 0.2732696835905484 0.04365524316066292 0.20462101232958987 1.8999223822044925e-06 5.721264140978137 0.37140900661663234 SET(ph)PPHWR ddPTM_PC-9_Lapatinib_30min_R1 2 SETPPHWR 8 0 Q13427;E9PG73;C9JM79 Q13427 PPIG Peptidyl-prolyl cis-trans isomerase G 1 SET(1)PPHWR;SET(1)PPHWR 96.14299999999999 0.013024 24043600.0 180555.0 133348.0 190041.0 133384.0 160767.0 169733.0 133088.0 145906.0 175926.0 127718.0 True False 177980.2525902682 133039.24089887692 174416.56255947458 143193.50431598016 151311.00114008322 162473.9152569482 139978.64543541466 152685.3254160401 156111.3612970913 149793.8861264621 1.1881676695403312 0.8881486710783361 1.1643770454838525 0.9559369078327427 1.0101280169228022 1.0846498442518615 0.9344750246831768 1.0193027857434511 1.0421744527363135 1.0 17.19261921548958 -4.729110018985136 24.855190082847106 1.0145765062047414 1.1881689720351962 0.34164228462536084 0.07362443730522611 4895.706064181177 3763644.880222159 0.0169309692314492 2.6865957716696074 1.865906944342656e-05 4.729110018985136 0.17359246583045485 SET(ph)SPVAPR ddPTM_PC-9_AZD4547_30min_R2 1 SETSPVAPR 9 0 A0A2R8Y661;H0Y8T6;H0Y8H7;A0A2R8YGD3;Q9Y4G8 A0A2R8Y661 RAPGEF2 Rap guanine nucleotide exchange factor 2 1 S(0.004)ET(0.909)S(0.087)PVAPR 106.88 0.0062098 22814000.0 70165.0 67243.0 83469.0 97758.0 107210.0 74824.0 70424.0 108130.0 71441.0 62630.0 True False 92476.01047733657 88977.98474146573 82362.1465223243 75221.40344604399 92325.74207930597 70145.24345159934 76691.59957063486 91420.99308020975 75217.2254103079 60437.34276308835 1.530113771544165 1.4722352220258161 1.3627691549110652 1.2446179796638062 1.527627421364614 1.1606275233933683 1.2689439353954137 1.512657388637616 1.2445488496268942 1.0 15.883152610753898 -13.994651626206977 0.12633334930096926 5.063972521674547e-18 1.5295347210479087 0.4991621531810302 0.12043762222091567 117.5847242857047 1.072776785679743 31.088706080724307 1.0544369251652463 1.012391228684116e-14 13.994651626206977 1.5295347210479087 SET(ph)SPVAPR ddPTM_PC-9_Lapatinib_30min_R1 1 SETSPVAPR 9 0 A0A2R8Y661;H0Y8T6;H0Y8H7;A0A2R8YGD3;Q9Y4G8 A0A2R8Y661 RAPGEF2 Rap guanine nucleotide exchange factor 2 1 S(0.184)ET(0.728)S(0.087)PVAPR 114.4 0.004991399999999999 18832000.0 84435.0 100520.0 113410.0 85694.0 103110.0 104350.0 81574.0 106530.0 106850.0 81973.0 True False 83230.94141651754 100287.25211593056 104085.86757525988 91996.22262680368 97045.27252205966 99887.19375173083 85797.5025753526 111479.77270688505 94815.42781961856 96141.92382784346 0.8657091319033207 1.0431167603376643 1.0826272601081006 0.9568793608866899 1.0093959914494095 1.0389556374032396 0.8924046779944397 1.1595334092388905 0.9862027307608261 1.0 16.552878052061246 -4.756243597368658 24.952703421169563 1.020223248216197 0.8657088853705691 0.3131889339193039 0.06797811606659115 192.56863207310968 924704.8712060925 0.01621283779253714 0.13365085519892397 1.7528970196771116e-05 4.756243597368658 -0.15451436284562792 SETAPAAPAAPAPAEKT(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 2 SETAPAAPAAPAPAEKTPVK 20 1 P10412 P10412 HIST1H1E Histone H1.4 1 SETAPAAPAAPAPAEKT(1)PVK;SETAPAAPAAPAPAEKT(1)PVK 152.37 7.8301e-06 133175000.0 119614.0 133762.0 131512.0 133073.0 142238.0 130786.0 161730.0 140664.0 149573.0 161273.0 True False 157648.76387424115 176997.95064152303 129768.0649515857 102395.07580735521 122490.70890659768 122607.93074495996 176123.65668747545 118927.61093715523 157479.12342066853 155626.88135768077 1.0129918591114953 1.1373224798788113 0.8338409394283036 0.6579523724569042 0.7870793775342353 0.787832601124785 1.1317045946753022 0.7641842456755348 1.011901813149688 1.0 17.24773175231787 -10.066702541053596 15.479933470011446 0.999999974581907 0.8963043370587742 0.03248099766645196 0.15567499594849551 0.0 0.0 0.1589567217031235 0.0385526678519935 8.576250525520444e-11 10.066702541053596 -0.10369563752313282 SETAPAAPAAPAPAEKT(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SETAPAAPAAPAPAEKTPVK 20 1 P10412 P10412 HIST1H1E Histone H1.4 1 SETAPAAPAAPAPAEKT(1)PVK;SETAPAAPAAPAPAEKT(1)PVK 133.68 5.9113e-06 93786000.0 96378.0 113450.0 104476.0 136701.0 246940.0 136327.0 170486.0 199491.0 135740.0 87801.0 True False 112692.89184773114 124712.56623507004 106967.10406743655 129042.08616062145 198553.87967362208 129177.77213003239 154336.33186824794 194254.57262818632 137724.94070514938 103718.62626766623 1.0865251103201565 1.202412437600406 1.0313201005129684 1.2441553730918404 1.9143512290763947 1.245463585264462 1.4880290784989074 1.8728995901553338 1.3278708527215082 1.0 16.662315477661693 -6.013711853482532 24.57409282491772 1.5141246467734768 1.1198883355506124 0.2864153819908076 0.2601043664625529 576.9980008934826 1034086.3259349007 0.07179182310601398 0.09696252987951047 9.689205042386083e-07 6.013711853482532 -0.3942363112228644 SETAPAAPAAPAPAEKT(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 4 SETAPAAPAAPAPAEKTPVK 20 1 P10412 P10412 HIST1H1E Histone H1.4 1 SETAPAAPAAPAPAEKT(1)PVK;SETAPAAPAAPAPAEKT(1)PVK;SETAPAAPAAPAPAEKT(1)PVK;SETAPAAPAAPAPAEKT(1)PVK 117.3 1.1903e-05 153711000.0 239625.0 331536.0 290464.0 277952.0 248205.0 237072.0 258624.0 265109.0 258221.0 241188.0 True False 236207.90355815642 330768.3487615108 266583.17114346416 298393.5173006909 233606.06988980508 226932.98320182375 272014.2852630494 277426.93196798605 229137.43179232304 282877.0244371908 0.8350197547082986 1.1693008628735546 0.9423995168001194 1.0548524324107678 0.8258219993461303 0.802231936840142 0.9615990757971462 0.9807333505432327 0.8100248942034529 1.0 18.10981547875459 -6.254661981515554 24.960345478383754 0.8942899061629374 1.0083155777358273 0.19407131221134466 0.10290726486414684 818.7777901698283 3015460.2252592747 0.02967452277153237 0.03741706005730667 5.563370950486121e-07 6.254661981515554 0.1140256715728899 SETAPAETATPAPVEKS(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 4 SETAPAETATPAPVEKSPAK 20 1 P16401 P16401 HIST1H1B Histone H1.5 1 SETAPAETATPAPVEKS(1)PAK;SETAPAETATPAPVEKS(1)PAK;SETAPAETATPAPVEKS(1)PAK;SETAPAET(0.001)AT(0.122)PAPVEKS(0.878)PAK 160.98 2.8236e-06 450518000.0 405821.0 463237.0 423868.0 528815.0 536208.0 449952.0 498805.0 441830.0 407165.0 438058.0 True False 534863.6363988211 612969.3011567349 418247.23336956894 406904.87186030624 461764.7748238086 421816.4303102472 543197.678686676 373555.3257433545 428686.91065617756 422721.72275447793 1.26528542917932 1.4500539436738509 0.9894150474317881 0.9625833023410574 1.0923611207271866 0.9978584198646527 1.2850006267649794 0.883690867148363 1.0141113824547037 1.0 18.689348725686322 -5.266797569321705 24.97536696556698 1.0320198728790935 1.3576696951179485 0.5997842303776949 0.10763881632672988 257.1231092584567 1198496.0911251623 0.02764697140611245 0.06029319440667673 5.410064347834009e-06 5.266797569321705 0.3256498222388551 SETAPAETATPAPVEKS(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SETAPAETATPAPVEKSPAK 20 1 P16401 P16401 HIST1H1B Histone H1.5 1 SETAPAETATPAPVEKS(1)PAK;SETAPAETATPAPVEKS(1)PAK;SETAPAETATPAPVEKS(1)PAK;SETAPAETAT(0.001)PAPVEKS(0.999)PAK;SETAPAET(0.001)AT(0.002)PAPVEKS(0.997)PAK;SETAPAETATPAPVEKS(1)PAK 123.29 3.3536e-06 470991700.0 357343.5 336968.3 362965.8 464922.0 696339.0 484338.2 502953.0 653106.0 479557.0 335200.2 True False 417834.6966941605 370420.2858780876 371620.2812274627 438873.9276374619 559896.3716613358 458938.65216332814 455309.6507756106 635962.6595230063 486569.61389228905 395969.3428166761 1.0552198150542367 0.9354771842768216 0.9385077101777387 1.1083532995650363 1.4139891934021616 1.1590257187557202 1.149860864320518 1.6060906508548596 1.2288062768474444 1.0 18.59502921110918 -6.014158658840822 4.738406312883565 1.2793561313996278 0.9766946539175096 0.39434236900523 0.15701538139351875 0.18040702942162792 10.839303649737053 0.0457332878624786 0.06411619700318422 9.679241842935686e-07 6.014158658840822 -0.30266147748211814 SETAPAETATPAPVEKS(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 4 SETAPAETATPAPVEKSPAK 20 1 P16401 P16401 HIST1H1B Histone H1.5 1 SETAPAETATPAPVEKS(1)PAK;SETAPAETATPAPVEKS(1)PAK;SETAPAET(0.001)AT(0.012)PAPVEKS(0.987)PAK;SETAPAETATPAPVEKS(1)PAK 127.22 9.7431e-06 388583000.0 505505.0 462016.0 461999.0 388095.0 322327.0 320452.0 364286.0 357337.0 309652.0 317741.0 True False 498296.40600173565 460946.23033817846 424015.22558771266 416636.80094696797 303368.35957926436 306747.0149700972 383146.9466149126 373940.1815428544 274775.7309798828 372662.10848673084 1.3371265676168904 1.2369012567710278 1.1378007474640002 1.11800151251976 0.814057433451317 0.8231237037103261 1.0281349723768738 1.003429576087876 0.7373320891025512 1.0 18.507508610709507 -5.783837084646011 1.5190473678718934 0.9055612952921251 1.2868516832749033 0.7091160270567601 0.09838751995733822 0.22973262816973825 1.073283550277977 0.03326148892537555 0.07343980369513894 1.6449886862798052e-06 5.783837084646011 0.38129038798277815 SETAPAETATPAPVEKS(ph)PAKK ddPTM_PC-9_AZD4547_30min_R2 2 SETAPAETATPAPVEKSPAKK 21 2 P16401 P16401 HIST1H1B Histone H1.5 1 SETAPAETATPAPVEKS(1)PAKK;SETAPAETATPAPVEKS(1)PAKK 78.441 0.00035180000000000004 18937900.0 158986.0 198865.0 168488.0 190766.0 193784.0 179768.0 202739.0 161983.0 169160.0 196063.0 True False 209540.24088576686 263144.22223296924 166253.73903189666 146787.84600531982 166880.4365553238 168527.07854173935 220782.3782425153 136952.2493490389 178101.4522530156 189198.89404693287 1.1075130324693552 1.3908338289107198 0.8787246874215638 0.7758388163141561 0.8820370615587598 0.890740294179174 1.16693271044041 0.7238533292645273 0.9413451022014726 1.0 17.529544129934052 -5.274024308085302 24.718203194966062 0.9006363493092376 1.2491734283767404 0.5226411785614455 0.13051057452132497 421.81318097465373 828488.8423169053 0.03344174712271832 0.07040678473380889 5.320784772375038e-06 5.274024308085302 0.34853707906750275 SETAPAETATPAPVEKS(ph)PAKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SETAPAETATPAPVEKSPAKK 21 2 P16401 P16401 HIST1H1B Histone H1.5 1 SETAPAETATPAPVEKS(1)PAKK 53.453 0.0075241 6401200.0 26029.0 24561.0 29117.0 33467.0 54783.0 33961.0 38877.0 56980.0 35841.0 28699.0 True False 30435.195603816235 26999.25376200582 29811.25970683742 31591.952491477954 44048.664413056016 32180.02537507635 35194.28911489433 55484.33537530039 36365.10682048963 33901.90151884101 0.8977430244407337 0.7963934927662084 0.8793388680652554 0.9318637325968485 1.299297751442524 0.9492100423096408 1.038121389602146 1.6366142572995477 1.0726568478844671 1.0 15.049078574293548 -6.108214929701896 4.675364089100957 1.1798194580133063 0.8586430338541994 0.36980001457853506 0.18620145400414015 0.24557252577111585 8.523596049947983 0.057065933541717934 0.07536166103356133 7.794442728192228e-07 6.108214929701896 -0.32117642415910697 SETAPAETATPAPVEKS(ph)PAKK ddPTM_PC-9_Lapatinib_30min_R1 2 SETAPAETATPAPVEKSPAKK 21 2 P16401 P16401 HIST1H1B Histone H1.5 1 SETAPAETAT(0.004)PAPVEKS(0.996)PAKK;SETAPAETATPAPVEKS(1)PAKK 83.404 0.00016977 15104700.0 145994.0 145627.0 121868.0 116349.0 88751.0 87398.0 103365.0 115071.0 90627.0 90271.0 True False 143912.09878797905 145289.80962879627 111848.48346408416 124905.693588886 83530.84067117958 83660.19127468877 108716.73393117054 120417.61874733849 80419.63291538198 105874.22207145352 1.3592742026558091 1.372286915418765 1.0564279130060448 1.179755479143812 0.7889629698039755 0.7901847082118563 1.0268480070417767 1.1373648503983318 0.7595770844116099 1.0 16.69199184359023 -5.484699876302828 1.3157409438849608 0.9329182017382209 1.4037943646100062 0.6109111328257701 0.13187528841233143 0.37926952995486607 1.1658328229806199 0.044051497786632615 0.16972749460888534 3.275669852355322e-06 5.484699876302828 0.47087616287178524 SETDLLDIR ddPTM_PC-9_AZD4547_30min_R2 1 SETDLLDIR 9 0 P50995;P50995-2;H0Y6E1 P50995 ANXA11 Annexin A11 0 93.162 0.029806 1329000.0 17498.0 13005.0 25554.0 29653.0 26316.0 23807.0 22757.0 25850.0 16910.0 22222.0 False True 23062.000018990027 17208.61192336394 25215.137263313005 22816.958984283065 22662.47764722524 22318.344526518544 24782.32891384946 21855.476473905655 17803.82807755079 21444.01454385037 1.0754516124688815 0.8024902188055527 1.1758589890783346 1.0640245993876376 1.0568206620492289 1.0407726818539633 1.1556758116896744 1.0191877285483972 0.8302469689686206 1.0 14.38828739823372 -8.021735510552494 23.036436883241077 0.9183212914427168 1.051004069641397 0.22179161089733745 0.10180289156712256 433.9157122853004 459880.1869564982 0.06641419329750002 0.02571421325403097 9.511838972893625e-09 8.021735510552494 0.13268277819868013 SETDLLDIR ddPTM_PC-9_Lapatinib_30min_R1 2 SETDLLDIR 9 0 P50995;P50995-2;H0Y6E1 P50995 ANXA11 Annexin A11 0 ; 133.86 0.0052887 5311600.0 51367.0 58870.0 69931.0 59387.0 51458.0 63931.0 57901.0 53537.0 71957.0 54718.0 False True 50634.49716044588 58733.69013196203 64181.543121466326 63754.51808922447 48431.34161032048 61196.82016043993 60898.830468231165 56024.52446642739 63852.44491919788 64175.93339284805 0.7889951027356422 0.9151980661103635 1.0000874117184075 0.9934334370948075 0.7546651688546817 0.9535789652770346 0.9489356406465279 0.8729833989866196 0.994959349143082 1.0 15.969744753465692 -8.278950543121146 22.48013460807696 0.9974798354356431 0.9083176802201864 0.19248411988395453 0.07649856677757451 454.53761100672585 583497.2535499205 0.07371932862430455 0.01929196599978742 5.260771719493669e-09 8.278950543121146 -0.08916215521545667 SETIQDTDTQSLVGS(ph)PSTR ddPTM_PC-9_AZD4547_30min_R2 4 SETIQDTDTQSLVGSPSTR 19 0 Q9NZN5-2;Q9NZN5;E9PMR6 Q9NZN5-2 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 SETIQDTDTQS(0.001)LVGS(0.976)PS(0.019)T(0.004)R;SETIQDTDTQSLVGS(0.919)PS(0.04)T(0.04)R;SETIQDTDTQSLVGS(0.997)PS(0.002)TR;SETIQDTDTQSLVGS(0.912)PS(0.08)T(0.007)R 340.33 1.2103999999999996e-199 29328300.0 143921.0 168553.1 165288.0 180036.5 175361.0 191199.0 159148.0 233559.0 174815.0 146913.4 True False 189684.88425723338 223034.59333948107 163096.17312273936 138531.86646119726 151015.1521011958 179243.29630469237 173311.86368947223 197467.8232018926 184055.36400810417 141770.00658295883 1.3379761264681642 1.573214241257505 1.1504279152819339 0.977159201725319 1.065212281081662 1.2643245255110114 1.2224861087810996 1.3928744729678868 1.298267302402934 1.0 17.1131928170916 -1.5228799095454186 0.0181954817580544 5.3020492224337065e-09 2.776501862856824 0.13586683036722136 0.1642401627786367 10668.592650060087 15.026957396120116 874.1147704730508 1495.776006073241 0.029999919575525204 1.5228799095454186 2.776501857554775 SETIQDTDTQSLVGS(ph)PSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SETIQDTDTQSLVGSPSTR 19 0 Q9NZN5-2;Q9NZN5;E9PMR6 Q9NZN5-2 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 SETIQDTDTQSLVGS(0.967)PS(0.032)T(0.001)R;SET(0.001)IQDT(0.001)DT(0.024)QS(0.068)LVGS(0.75)PS(0.121)T(0.036)R;SETIQDTDTQSLVGS(0.999)PS(0.001)TR 293.09 4.402999999999999e-121 15344500.0 42938.5 65168.0 63492.1 51249.7 76091.0 67332.0 82964.0 63937.0 70891.0 65927.0 True False 50207.13997596773 71637.44835969199 65005.992459130095 48378.34546276918 61181.51477381385 63800.99138878838 75105.04931265509 62258.72149685125 71927.64676240414 77879.0432221551 0.6446810065802755 0.9198552703753877 0.8347045593985563 0.6211985081116979 0.7855966411822696 0.8192318337398143 0.9643807397378135 0.7994284331312872 0.9235815411499829 1.0 16.248947539581835 -7.016040743451558 3.6056905634504455 0.9051690267587119 0.767412549468793 0.3860105306665841 0.09427651832894664 0.29663392537367494 8.24843735224076 0.03713820939987726 0.03000980035977386 9.637386059908234e-08 7.016040743451558 -0.1377564772899189 SETIQDTDTQSLVGS(ph)PSTR ddPTM_PC-9_Lapatinib_30min_R1 2 SETIQDTDTQSLVGSPSTR 19 0 Q9NZN5-2;Q9NZN5;E9PMR6 Q9NZN5-2 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 SETIQDTDTQSLVGS(0.492)PS(0.492)T(0.016)R;SETIQDTDTQSLVGS(1)PSTR 267.69 1.5537999999999997e-78 12476600.0 24675.9 29995.0 25579.0 25728.0 41527.0 54704.0 62797.0 56692.0 55103.0 41731.0 True False 24324.017140994165 29925.54842038729 23475.993357795367 27620.12294609202 39084.46350522328 52364.437441252376 66048.32139191915 59326.11728432116 48896.71987968591 48944.14774693774 0.496974985993418 0.6114224028399723 0.47964862886521864 0.5643192131753916 0.7985523357625254 1.0698814843400482 1.3494631009496239 1.212118711128911 0.9990309798119879 1.0 15.578848746605862 -6.594361771919168 2.1677320255958477 1.163475894964089 0.5371482208865326 0.8809935939288606 0.1021000826266069 0.09816156520840552 0.9376130382418799 0.03885424294192289 0.03993972561717287 2.5447095993025596e-07 6.594361771919168 -0.6263276740775565 SETITEEELVGLMNK ddPTM_PC-9_Lapatinib_30min_R1 1 SETITEEELVGLMNK 15 0 P16152 P16152 CBR1 Carbonyl reductase [NADPH] 1 0 222.25 2.641099999999999e-77 0.0 3860.0 4024.2 2924.6 3613.2 3394.0 2771.2 3168.1 4146.9 3697.1 3661.5 False True 3804.9556921626954 4014.8822121461126 2684.150677282472 3878.9267812818603 3194.3715928607344 2652.6822359827174 3332.1287163676466 4339.580113002743 3280.6936658110594 4294.385396357925 0.8860303258737989 0.9349142756379389 0.6250372124399697 0.9032553958877525 0.7438483736391909 0.6177094021958209 0.7759267994888466 1.0105241408195798 0.7639495208309485 1.0 12.068235955240302 -11.346676787679826 8.65518193420129 1.005798916375347 0.8057294688415462 0.18388120934346797 0.12208741792202076 0.014195496152805452 0.0002889911480474481 0.12283187300518683 0.02931341960999803 4.50114716388185e-12 11.346676787679826 -0.20006944753380074 SETSGPQIK ddPTM_PC-9_Lapatinib_30min_R1 2 SETSGPQIK 9 0 Q9Y266;A0A0A0MSS4;A0A0A0MSU9 Q9Y266 NUDC Nuclear migration protein nudC 0 ; 104.17 0.012537999999999999 5183800.0 28281.0 26099.0 26314.0 24658.0 30234.0 25755.0 27179.0 23689.0 25417.0 27430.0 False True 27877.707753899766 26038.569369017794 24150.564494977414 26471.431576676678 28455.695562331028 24653.518687837353 28586.19563213165 24789.677420946235 22554.269807124412 32171.238951822466 0.8665413164736239 0.8093741558418514 0.7506880456529421 0.82282909950464 0.8845072956296277 0.7663217050719384 0.8885637160241313 0.7705540174585638 0.7010693570396902 1.0 14.973483876473633 -10.72038249602466 4.9324461628685485 1.00002112934953 0.8080642400373195 0.4981761021881207 0.058182798574004456 1.351948776012419e-05 2.1995327468390753e-06 0.05633718311940144 0.01366227061512133 1.9037832610239416e-11 10.72038249602466 -0.19195688931221055 SETSWES(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 SETSWESPK 9 0 Q86UE4;E5RJU9 Q86UE4 MTDH Protein LYRIC 1 SETSWES(1)PK 128.81 0.0013181 14382000.0 87040.0 67884.0 71408.0 57115.0 51699.0 49667.0 91546.0 51448.0 62380.0 61218.0 True False 114716.90945553167 89826.17545602751 70461.08326284173 43948.01916795358 44521.486239698206 46561.31463849278 99693.41665189892 43497.893757427395 65677.27944870602 59074.77645330898 1.9418932468783974 1.5205504082952148 1.192743967783478 0.7439388146087839 0.753646292252781 0.7881758922150729 1.6875800914912265 0.7363192274084506 1.1117651795198153 1.0 15.850254644411919 -5.080793014101715 1.8957563688155998 0.9781396552449377 1.9772712401644705 0.5639304723964689 0.2725244901047561 0.35264543523283975 2.0042462156484984 0.07824326630295854 0.50403175712164 8.302463708495304e-06 5.080793014101715 0.9991315849195328 SETSWES(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SETSWESPK 9 0 Q86UE4;E5RJU9 Q86UE4 MTDH Protein LYRIC 1 S(0.001)ETSWES(0.998)PK;SETS(0.001)WES(0.999)PK 126.71 0.0013858 24169000.0 129926.0 137639.0 85293.0 99985.0 139940.0 72610.0 106268.0 101730.0 74367.0 66776.0 True False 151919.905644528 151302.89029553844 87326.708595504 94383.16460574351 112519.76156769533 68802.2037774003 96201.52572630568 99059.69529184484 75454.47668645853 78881.9602014748 1.9259144328627835 1.918092424542838 1.1070555089206735 1.1965113996239016 1.4264321180699011 0.8722172167333382 1.2195630722232873 1.255796572991258 0.956549209651205 1.0 16.26740778240383 -5.259533801706659 24.862846841093138 1.1454605468285668 1.9220035245778158 0.81205450242984 0.1523910008515269 58.49702483467332 763218.5166693085 0.03846346153309495 0.09176215446022387 5.501311014223804e-06 5.259533801706659 0.776542977749249 SETSWES(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 SETSWESPK 9 0 Q86UE4;E5RJU9 Q86UE4 MTDH Protein LYRIC 1 SET(0.004)S(0.163)WES(0.832)PK;SETS(0.002)WES(0.997)PK 134.57 0.0011079 23461000.0 330550.0 424940.0 110428.0 122657.0 137880.0 103379.0 152858.0 105353.0 150133.0 64430.0 True False 325836.2963845537 423956.07753823535 101349.03610440691 131677.60495175747 129770.16948250972 98957.72115821921 160772.23930006177 110248.08499003534 133223.44056942244 75566.63965242136 4.311906654620086 5.610360332129055 1.3411875474491792 1.7425361979495957 1.7172944315031684 1.3095424331872925 2.127555757931737 1.4589518006508668 1.762992785999233 1.0 16.205461849046785 -5.265514467438015 24.999997531962915 1.5977164747976977 4.961133629189599 0.9154065529259521 0.41372480825241975 71.75298476345135 440195.5150874552 0.09846310689008268 0.2175490094378525 5.426071754225516e-06 5.265514467438015 3.3634171543919016 SEVPEDLAGFIELFQT(ph)PSHTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEVPEDLAGFIELFQTPSHTK 21 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 SEVPEDLAGFIELFQT(0.992)PS(0.006)HT(0.002)K 148.49 0.00021878 1809300.0 13986.0 18705.0 16681.0 16277.0 16802.0 10436.0 10126.0 11025.0 10980.0 9571.5 True False 16353.553563908485 20561.908782961553 17078.738303044775 15365.052460745997 13509.768714166212 9888.717788471968 9166.791974108595 10735.605431953087 11140.561727880813 11306.737182047687 1.4463547971977184 1.818553704034865 1.5104921984179134 1.3589289477022526 1.194842375536631 0.8745863310746105 0.8107371584318067 0.949487483356258 0.985302970123802 1.0 13.464895046241782 -6.222511571540274 1.4154150008968245 0.9122699030467207 1.6284528945744565 0.8766447240044617 0.10944332347567144 0.12838215202892786 0.516939453738651 0.0412109178155414 0.059435432314508305 5.990849761053304e-07 6.222511571540274 0.7161829915277358 SEVQQPVHPKPLS(ph)PDSR ddPTM_PC-9_AZD4547_30min_R2 8 SEVQQPVHPKPLSPDSR 17 1 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VRN8;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 S(0.001)EVQQPVHPKPLS(0.871)PDS(0.128)R;S(0.004)EVQQPVHPKPLS(0.757)PDS(0.239)R;SEVQQPVHPKPLS(0.862)PDS(0.138)R;SEVQQPVHPKPLS(0.998)PDS(0.002)R;SEVQQPVHPKPLS(0.983)PDS(0.017)R;SEVQQPVHPKPLS(0.743)PDS(0.257)R;SEVQQPVHPKPLS(0.978)PDS(0.022)R;S(0.002)EVQQPVHPKPLS(0.972)PDS(0.026)R 112.14 0.0001319 1236769000.0 873578.5 789699.3 1077484.2000000002 1387639.0 1173453.0 1063903.9 873221.9 1113956.2 929386.4 1040573.7 True False 1151358.291438407 1044954.1553135061 1063196.0554923313 1067740.2673588379 1010539.3062231883 997377.8209479057 950936.9574450317 941819.8654569166 978511.8677240589 1004143.5314889854 1.146607288034934 1.0406422214999533 1.0588088476911068 1.0633343081696185 1.006369382995197 0.9932622077134259 0.9470129793446393 0.9379335084301617 0.9744741035906304 1.0 19.937534071050408 -6.1895454382470705 0.7991116159822368 0.9577872653237954 1.1004108425951218 0.7561751542919638 0.029285831449215392 0.34064520904655393 0.46090746217255846 0.01569594906414644 0.029492114569672725 6.463303678689987e-07 6.1895454382470705 0.14262357727132635 SEVQQPVHPKPLS(ph)PDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 9 SEVQQPVHPKPLSPDSR 17 1 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VRN8;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 SEVQQPVHPKPLS(0.975)PDS(0.025)R;SEVQQPVHPKPLS(0.984)PDS(0.016)R;SEVQQPVHPKPLS(0.88)PDS(0.12)R;SEVQQPVHPKPLS(0.999)PDS(0.001)R;S(0.001)EVQQPVHPKPLS(0.907)PDS(0.092)R;SEVQQPVHPKPLS(0.893)PDS(0.107)R;SEVQQPVHPKPLS(1)PDSR;SEVQQPVHPKPLS(0.971)PDS(0.029)R;SEVQQPVHPKPLS(0.986)PDS(0.014)R 185.59 1.513e-07 1327377000.0 951269.0 914485.0 987405.0 1203033.0 1274181.0 1110789.0 1136963.0 1247661.0 1057064.0 803095.0 True False 1112300.0532808255 1005269.0271791827 1010948.4799543172 1135630.9612956094 1024514.3798348391 1052537.269407723 1029261.6337407092 1214911.2207561026 1072521.5612313831 948689.766203478 1.172459209433757 1.0596393710476366 1.065625999108212 1.197051978161674 1.0799256156570556 1.1094641334857318 1.0849296265307766 1.2806201395193764 1.1305292830589524 1.0 19.85557685890889 SEVQQPVHPKPLS(ph)PDSR ddPTM_PC-9_Lapatinib_30min_R1 7 SEVQQPVHPKPLSPDSR 17 1 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VRN8;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 SEVQQPVHPKPLS(0.914)PDS(0.086)R;SEVQQPVHPKPLS(0.971)PDS(0.029)R;SEVQQPVHPKPLS(0.936)PDS(0.064)R;SEVQQPVHPKPLS(0.903)PDS(0.097)R;SEVQQPVHPKPLS(0.946)PDS(0.054)R;SEVQQPVHPKPLS(0.733)PDS(0.267)R;SEVQQPVHPKPLS(0.959)PDS(0.041)R 130.09 0.0001393 1189044000.0 582699.0 500165.0 520670.0 502865.0 574853.0 520083.0 454177.0 465200.0 544017.0 421366.0 True False 574389.6054060913 499006.8986725469 477862.5224443213 539847.3696084644 541041.2767444826 497840.26246268785 477692.0627548715 486814.8902960943 482744.07670702355 494198.55166509695 1.1622648497669765 1.0097295853888062 0.9669444008572367 1.0923693883552743 1.0947852334280606 1.0073689224408306 0.9665994793901959 0.9850593221203806 0.976822119531755 1.0 18.914731257040692 -6.952580248474089 6.150801733556708 0.9815899306852455 1.0579775473443576 0.3855671352411498 0.049638970715786525 0.23158799325688414 20.55718437889915 0.018463833432226986 0.016138743451455495 1.1153720350459293e-07 6.952580248474089 0.07638761665911209 SEVQQPVHPKPLSPDS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SEVQQPVHPKPLSPDSR 17 1 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VRN8;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 SEVQQPVHPKPLS(0.201)PDS(0.799)R;SEVQQPVHPKPLS(0.45)PDS(0.549)R 86.439 0.0014462 359410000.0 53307.7 63162.0 64184.0 77579.0 81100.0 71484.0 76438.0 85109.0 64104.0 68131.0 True False 62331.64073493239 69432.30593688416 65714.38997917555 73232.50014451146 65209.03718122118 67735.25319960996 69197.23927680374 82874.97893043938 65041.39972714683 80482.61097530082 0.7744733921972443 0.8626994712956334 0.8165042011291425 0.9099170523553922 0.8102251702698 0.8416135159978485 0.8597787576503895 1.0297252776239174 0.808142267490642 1.0 16.29638948861954 -14.522878730178164 0.04586403040024217 1.6427231460635807 0.5245877878477654 0.38559337571428376 0.06287290552736345 662.3825562355556 2.2480853792674322 53.69449453285592 13.514468197239529 3.0000001043221234e-15 14.522878730178164 -1.1181353582158153 SEVS(ph)SPIQR ddPTM_PC-9_AZD4547_30min_R2 1 SEVSSPIQR 9 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;Q9HAU0-3;H0YG48 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 SEVS(0.5)S(0.5)PIQR 96.665 0.0050318 16252000.0 49022.0 46109.0 72954.0 88406.0 90660.0 75851.0 59028.0 81345.0 62559.0 62104.0 True False 64609.97627905644 61012.83253936086 71986.58229270313 68025.36255908445 78073.42390551143 71108.02497924805 64281.37764761195 68774.99937214136 65865.74102327036 59929.75786298645 1.0780950663403326 1.018072402008541 1.2011825987563878 1.1350848891231373 1.3027488628271398 1.186522814622708 1.0726120034486761 1.1475934798431393 1.0990490095730898 1.0 15.87098492448108 -8.802772489577379 1.064555203370429 1.0001654874242256 1.1479808930717703 0.25321206374697025 0.07457134129430094 1.518479887803032 3.1599773952760173 0.07756935994668743 0.02462683306182473 1.5748076304599342e-09 8.802772489577379 0.1478154056475447 SEVS(ph)SPIQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SEVSSPIQR 9 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;Q9HAU0-3;H0YG48 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 SEVS(0.5)S(0.5)PIQR;SEVS(0.5)S(0.5)PIQR 94.309 0.0057887 29092000.0 137779.0 156602.0 159655.0 174120.0 192509.0 162697.0 167828.0 158578.0 156708.0 118412.0 True False 161102.26344070863 172148.4116134373 163461.78069495916 164364.62090465683 154788.24338741944 154164.88290830047 151930.11687050163 154415.49552727985 158999.55803759114 139879.15825112388 1.1517245703715424 1.2306937914537681 1.1685928249689463 1.1750472547852655 1.1065854650735703 1.102129043638721 1.0861526389638603 1.1039206802349997 1.136692270853822 1.0 17.093821493925205 -1.5228789249496033 0.04389080653053374 0.6955233651956765 1.8728445847579405 0.7173816254611639 0.031385527240275275 338.18626862797726 1.1309203216414723 7.846500527995778 28.4471612251272 0.029999987588889377 1.5228789249496033 1.177321219562264 SEVS(ph)SPIQR ddPTM_PC-9_Lapatinib_30min_R1 1 SEVSSPIQR 9 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;Q9HAU0-3;H0YG48 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 SEVS(0.5)S(0.5)PIQR 95.775 0.0053178999999999995 14388000.0 97716.0 92396.0 104030.0 84440.0 81954.0 80937.0 80934.0 79615.0 91505.0 76532.0 True False 96322.55192108022 92182.06273879354 95477.05496741262 90649.99928358271 77133.6268477634 77475.51318336223 85124.3665068966 83314.203548847 81198.74330963222 89760.45422752027 1.073106779037979 1.0269785679240782 1.0636872973637388 1.009910211169472 0.8593275013097524 0.8631363761482446 0.9483504427364822 0.9281838451671196 0.9046160027645777 1.0 16.453792356188366 -6.078260873761711 4.885292108506346 0.9129874455331513 1.0500911516354645 0.7132863033336186 0.03980310073488036 0.11616251866812084 4.968608902232776 0.011900950083904635 0.01580050519379143 8.351012355602153e-07 6.078260873761711 0.13710370610231326 SEWLDPS(ph)QKSPLHVGETR ddPTM_PC-9_AZD4547_30min_R2 1 SEWLDPSQKSPLHVGETR 18 1 O15164-2;O15164 O15164-2 TRIM24 Transcription intermediary factor 1-alpha 1 SEWLDPS(0.591)QKS(0.407)PLHVGET(0.002)R 67.646 0.006025 15990000.0 36662.0 36185.0 44539.0 61371.0 59100.0 45859.0 45110.0 57225.0 42863.0 43447.0 True False 48319.753383027324 47881.09361375809 43948.38375873439 47222.864122498126 50894.98514025733 42991.42948047276 49124.702610350585 48382.19114968092 45128.65067345116 41925.933754237594 1.1525027365226777 1.142040005463649 1.0482386395101428 1.1263401883738642 1.2139260973552726 1.0254137625766646 1.1717020519640875 1.1539919762619661 1.076389876919315 1.0 15.355555294707148 -8.56229205979707 4.2273322970402 1.0000852030520369 1.1273641288345695 0.3680169443327761 0.05263117689762932 0.23922772381462126 14.015698795433375 0.04982432159961047 0.013026369510289123 2.7397311035574444e-09 8.56229205979707 0.12727892578253264 SEWLDPS(ph)QKSPLHVGETR ddPTM_PC-9_Lapatinib_30min_R1 2 SEWLDPSQKSPLHVGETR 18 1 O15164-2;O15164 O15164-2 TRIM24 Transcription intermediary factor 1-alpha 1 SEWLDPS(0.475)QKS(0.475)PLHVGET(0.05)R;SEWLDPS(0.5)QKS(0.5)PLHVGETR 65.107 0.0072086 26438000.0 51206.0 31783.0 42315.0 34588.0 42903.0 38010.0 33069.0 34708.0 29073.0 31831.0 True False 50475.79304996969 31709.40841624171 38836.02404062358 37131.71690218562 40379.52989054336 36384.40090563764 34781.151012140304 36320.660387783464 25798.492587737663 37332.945937858596 1.3520442006903932 0.8493679676129129 1.040261438389215 0.9946098806130133 1.0816057740997953 0.974592280132411 0.9316476409344764 0.9728849271161162 0.6910382221290479 1.0 15.188161735558445 -7.36819676639802 1.226163859011174 0.8661242450802131 1.048175407490909 0.2362681055172129 0.1396058730163378 0.734570591977571 2.1160306661145536 0.09254836481883989 0.04844280135054351 4.28354401308321e-08 7.36819676639802 0.18205116241069597 SEWLDPSQKS(ph)PLHVGETR ddPTM_PC-9_AZD4547_30min_R2 2 SEWLDPSQKSPLHVGETR 18 1 O15164-2;O15164 O15164-2 TRIM24 Transcription intermediary factor 1-alpha 1 SEWLDPS(0.011)QKS(0.989)PLHVGETR;SEWLDPS(0.007)QKS(0.993)PLHVGETR 83.395 0.0010565 28495000.0 71023.0 56272.0 69009.0 99537.0 92819.0 83454.0 72182.0 88014.0 70461.0 83003.0 True False 93606.83662982806 74460.82354106382 68093.89557032034 76590.28248132009 79932.68402256412 78235.60818734334 78606.05816493742 74413.45866051584 74185.42461101749 80097.0902341471 1.1686671308057266 0.9296320668253137 0.8501419386305055 0.9562180381013144 0.9979474134315945 0.9767596795169201 0.9813846911935133 0.929040723489251 0.9261937530333738 1.0 16.2894622129323 -4.758554167300862 24.998791480211978 0.9479202218350844 1.1686674286076235 0.7059833574740346 0.04237805280470368 47.05929016220099 407668.4527030589 0.011374535401347984 0.07725363174028284 1.74359587422266e-05 4.758554167300862 0.22074720677253912 SEWLDPSQKS(ph)PLHVGETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SEWLDPSQKSPLHVGETR 18 1 O15164-2;O15164 O15164-2 TRIM24 Transcription intermediary factor 1-alpha 1 S(0.002)EWLDPS(0.222)QKS(0.775)PLHVGET(0.001)R;S(0.001)EWLDPS(0.243)QKS(0.756)PLHVGET(0.001)R 52.568999999999996 0.022837 46912000.0 62136.0 61813.0 68367.0 77269.0 88540.0 73314.0 87013.0 76474.0 79419.0 63517.0 True False 72654.3975580593 67949.38613211448 69997.12856329138 72939.86843947785 71191.22258970814 69469.28477807924 78770.49872043372 74466.6385309008 80580.35262901339 75032.12929970461 0.9683104856034697 0.9056038628558817 0.9328954038302488 0.972115134146473 0.9488098399199821 0.9258605003810377 1.0498235816525578 0.9924633517123705 1.073944633866743 1.0 16.195220879899786 -7.2592594494776845 24.99973331914702 1.0284298396459173 0.9418277220522444 0.6946589473405904 0.028187683674453217 107.98413093339151 1238384.8845512406 0.010744830917642355 0.007899157156824377 5.504787396789984e-08 7.2592594494776845 -0.08660211759367287 SEWLDPSQKS(ph)PLHVGETR ddPTM_PC-9_Lapatinib_30min_R1 2 SEWLDPSQKSPLHVGETR 18 1 O15164-2;O15164 O15164-2 TRIM24 Transcription intermediary factor 1-alpha 1 SEWLDPS(0.028)QKS(0.972)PLHVGETR;SEWLDPS(0.077)QKS(0.923)PLHVGETR 99.74700000000001 0.00026554 42629000.0 124896.0 101787.0 109060.0 99476.0 116805.0 114010.0 103417.0 100458.0 107575.0 89696.0 True False 123114.96013687845 101551.31845527468 100093.50778377413 106791.79688220799 109934.75954746558 109134.05807029076 108771.42623673283 105125.64541995942 95458.77068503012 105199.83408759248 1.1702961435696686 0.9653182377713644 0.9514607000276571 1.0151327500506322 1.045008868131205 1.0373976253557826 1.0339505492581533 0.9992947834159958 0.907404194245671 1.0 16.682772903770484 -8.034383745477344 6.780614166958118 0.9529748620945732 1.0252250059824692 0.20927286647104182 0.05923293267508086 0.34786595445790314 50.5811648263791 0.03871118861468159 0.015114382918152362 9.238814653919394e-09 8.034383745477344 0.07225014388789608 SEYQWIT(ph)SPSVK ddPTM_PC-9_AZD4547_30min_R2 1 SEYQWITSPSVK 12 0 A0A2R8Y589;A0A2R8Y4C1;A0A2R8Y7U5;A8MST6;A0A2U3TZI9;A0A2R8Y5W6;A0A2R8Y432;A0A2R8YCP0;A0A2R8Y7A4;Q5JTW2;Q5JTW2-3;Q5JTW2-5;Q5JTW2-2 A0A2R8Y589 CEP78 Centrosomal protein of 78 kDa 1 SEYQWIT(0.475)S(0.311)PS(0.214)VK 89.01299999999999 0.018882 2495800.0 19418.0 22480.0 26618.0 24753.0 24789.0 25077.0 27348.0 27372.0 22560.0 24589.0 True False 25592.5200805091 29746.220379640232 26265.027928107756 19046.578280037727 21347.475239286618 23508.93122575318 29781.919019903962 23142.2863459863 23752.47554284717 23728.14659430911 1.0785722339833799 1.2536259526807914 1.1069144327693543 0.8026997896500607 0.89966888709321 0.9907613783619953 1.2551304376654 0.9753094812528121 1.0010253202221826 1.0 14.53431179556275 -5.533336017163498 24.97024673730001 0.9924719225499717 1.169641910402893 0.29481513986591956 0.11374958224708874 255.04637293355745 609006.890792342 0.03319761181180905 0.05757337489604708 2.928626466397728e-06 5.533336017163498 0.17716998785292126 SEYQWIT(ph)SPSVKEPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SEYQWITSPSVKEPSK 16 1 A0A2R8Y589;A0A2R8Y4C1;A0A2R8Y7U5;A8MST6;A0A2U3TZI9;A0A2R8Y5W6;A0A2R8Y432;A0A2R8YCP0;A0A2R8Y7A4;Q5JTW2;Q5JTW2-3;Q5JTW2-5;Q5JTW2-2 A0A2R8Y589 CEP78 Centrosomal protein of 78 kDa 1 SEYQWIT(0.5)S(0.5)PSVKEPSK 104.89 0.0032734 0.0 19280.0 15512.0 20947.0 20549.0 23080.0 25642.0 28481.0 24975.0 22214.0 22558.0 True False 22543.72320264233 17051.928844763417 21446.45592193987 19397.706150756876 18557.6396811663 24297.28837983887 25783.073495416447 24319.43271319985 22538.837725240854 26647.58683097024 0.8459949242548922 0.6399051798921395 0.8048179393495574 0.7279348135273758 0.6964097649397026 0.9118007020283047 0.9675575375347294 0.9126317091097881 0.8458115876761444 1.0 14.701717269958825 -6.785583688791169 11.495346473242831 0.9246948458364518 0.739887960280927 0.6718345940363515 0.06445640331354009 0.3620586348954587 170.24012659565344 0.02154090012371589 0.019177294163136075 1.638386312898264e-07 6.785583688791169 -0.18480688555552482 SEYQWITS(ph)PSVK ddPTM_PC-9_Lapatinib_30min_R1 2 SEYQWITSPSVK 12 0 A0A2R8Y589;A0A2R8Y4C1;A0A2R8Y7U5;A8MST6;A0A2U3TZI9;A0A2R8Y5W6;A0A2R8Y432;A0A2R8YCP0;A0A2R8Y7A4;Q5JTW2;Q5JTW2-3;Q5JTW2-5;Q5JTW2-2 A0A2R8Y589 CEP78 Centrosomal protein of 78 kDa 1 SEYQWIT(0.061)S(0.932)PS(0.007)VK;SEYQWIT(0.034)S(0.738)PS(0.228)VK 94.54700000000001 0.0048749 2631200.0 46809.0 57216.0 60606.0 46127.0 61145.0 52908.0 57121.0 59281.0 50267.0 48786.0 True False 46141.49507628072 57083.519867340576 55623.2086259254 49519.3334551612 57548.57131569523 50645.2481745719 60078.44588480048 62035.41167593033 44605.40112502351 57218.59509674115 0.8064073401010274 0.9976393123743742 0.972117692366994 0.8654412673264245 1.005766940247243 0.8851186941752851 1.0499811430746264 1.0841827131729684 0.7795612781056204 1.0 15.80419645477351 -6.706006558739811 1.550346167211967 0.977298582032387 0.9242707098763293 0.04859773285321389 0.09611936630468823 1.3390641587716101 6.683798261734599 0.04086966988983624 0.038819802843113156 1.9678565708012852e-07 6.706006558739811 -0.05302787215605764 SEYQWITS(ph)PSVKEPSK ddPTM_PC-9_Lapatinib_30min_R1 1 SEYQWITSPSVKEPSK 16 1 A0A2R8Y589;A0A2R8Y4C1;A0A2R8Y7U5;A8MST6;A0A2U3TZI9;A0A2R8Y5W6;A0A2R8Y432;A0A2R8YCP0;A0A2R8Y7A4;Q5JTW2;Q5JTW2-3;Q5JTW2-5;Q5JTW2-2 A0A2R8Y589 CEP78 Centrosomal protein of 78 kDa 1 SEYQWIT(0.361)S(0.59)PS(0.048)VKEPSK 71.07300000000001 0.008798700000000001 6265000.0 36496.0 24935.0 23540.0 26067.0 24142.0 23296.0 20689.0 19412.0 26806.0 18119.0 True False 35975.560347453305 24877.26453950184 21604.63206702776 27984.05413696287 22722.01502499821 22299.684385628385 21760.17518794554 20313.95238699009 23786.826000305977 21250.84500795011 1.6929002274495233 1.1706482509375538 1.0166481407654753 1.3168443008498634 1.0692287773261593 1.0493551845719968 1.02396752598802 0.9559126886196987 1.1193355366060567 1.0 14.375232588542904 -4.761955119808509 3.394055447660054 1.0741404486957586 1.7883551071652484 0.799221603461717 0.09331637270124303 0.14685357145839883 2.6300649371693856 0.024520073235119188 0.28257003118353957 1.72999512847009e-05 4.761955119808509 0.7142146584694897 SFAPS(ph)TPLTGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFAPSTPLTGR 11 0 P28749;P28749-2;H0YE05 P28749 RBL1 Retinoblastoma-like protein 1 1 S(0.142)FAPS(0.459)T(0.319)PLT(0.08)GR;S(0.001)FAPS(0.499)T(0.499)PLT(0.002)GR 95.618 0.0061442 63067000.0 160465.0 185540.0 223174.0 212047.0 232229.0 181020.0 210491.0 194151.0 182970.0 149601.0 True False 187628.5551717845 203959.185008858 228495.31455210762 200166.69405565 186725.39451982535 171526.99253250248 190551.76865712967 189054.74196998883 185645.59010476808 176722.4770591355 1.0617130219887059 1.1541213568470323 1.292961248362582 1.132661206353901 1.056602406367033 0.9706008844313874 1.0782542878989103 1.0697832280085495 1.0504922361553743 1.0 17.431126020152355 -6.204283442739757 3.786215780015864 1.038979926476695 1.173178577272972 0.5013366229056554 0.06049800921025583 0.20167738976853317 5.896013050614371 0.019354155196918247 0.024963285976212293 6.247648062937611e-07 6.204283442739757 0.1341986507962769 SFATASHR ddPTM_PC-9_AZD4547_30min_R2 2 SFATASHR 8 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 0 ; 107.01 0.0032034999999999998 1418640.0 9161.599999999999 9067.7 18544.1 27523.0 19317.6 18181.6 12936.0 18939.9 14734.2 17187.0 False True 12074.798226881865 11998.656696461905 18298.193117500316 21177.997576111127 16635.68468604798 17044.701677798534 14087.278939647427 16013.173650604474 15513.019731534529 16585.288361315655 0.7280427065136666 0.7234517986704508 1.1032785634393867 1.276914643552881 1.003038616129815 1.0277000499764861 0.8493840223185563 0.9655046871511979 0.9353482070120566 1.0 14.01761647541512 -5.251744330427542 24.62379275321278 1.0216445852023956 0.7257471883083947 0.5510576136033813 0.10628323090810989 451.99495306572663 1147983.616837592 0.030492238531268118 0.07847600186718981 5.600872283410929e-06 5.251744330427542 -0.29589739689400096 SFATASHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFATASHR 8 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 0 ; 122.52 0.0027908 2212300.0 10913.5 11405.900000000001 18742.7 21461.9 22921.0 23420.1 19474.6 18388.4 19589.4 14744.1 False True 12760.939998549635 12538.20237303294 19189.597050085566 20259.459323418614 18429.794589775236 22191.908727270253 17629.824904105804 17905.7239841203 19875.857915496228 17417.088615768625 0.7326678000016874 0.7198793466366952 1.1017683536795118 1.1631943644747056 1.0581443889014697 1.2741457092420558 1.0122142278213235 1.0280549395557008 1.1411699368344228 1.0 14.088215867399981 -5.262119078438508 24.410634513615218 1.1025653464850997 0.7262735308816836 0.7832697885480384 0.07803615789501477 16.949645469378048 608771.2090471975 0.019977010977585134 0.04600723323838065 5.468659981115018e-06 5.262119078438508 -0.3762918156034162 SFATASHR ddPTM_PC-9_Lapatinib_30min_R1 2 SFATASHR 8 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 0 ; 136.27 0.0029298 2156880.0 19557.8 18741.9 22611.0 18330.0 21887.0 21582.0 17801.1 19016.6 22708.0 15532.2 False True 19278.902185538733 18698.5042820489 20752.010860984068 19678.049347087486 20599.649691497623 20658.988170099226 18722.753856548752 19900.180659511436 20150.385914159076 18216.920074644444 1.0582964686973857 1.026436093776069 1.139161327817875 1.080207261515998 1.1307976105230668 1.1340549382358998 1.0277672504370463 1.0924009425286918 1.1061357151259483 1.0 14.152991443594095 -10.204672401838893 10.669219585105727 1.0000000010598986 1.0887234779648338 0.31498477714970563 0.039089089406468935 0.0 0.0 0.038809909204783916 0.009412785586585601 6.24205510289602e-11 10.204672401838893 0.0887234769049352 SFCPIELNINGS(ph)PGAESDLATFCTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFCPIELNINGSPGAESDLATFCTSK 26 0 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 SFCPIELNINGS(0.999)PGAES(0.001)DLATFCTSK 98.289 0.0003047 0.0 7866.9 7569.8 7634.8 8784.3 11912.0 8151.4 7014.7 9600.2 8387.1 6851.2 True False 9198.610791642472 8321.279716934636 7816.842587140235 8292.144150084847 9577.929111007492 7723.926234280419 6350.216833969937 9348.20492225271 8509.745470665688 8093.268325930636 1.1365755367544588 1.0281729681781904 0.9658449803394336 1.0245729927817935 1.1834439098380118 0.9543642843933823 0.7846294696079699 1.1550593092658608 1.051459698104988 1.0 12.982506712336944 SFDTVIGAGT(ph)PPGLAEPLLVVRPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFDTVIGAGTPPGLAEPLLVVRPK 24 1 Q9H6A9;Q9H6A9-2 Q9H6A9 PCNXL3 Pecanex-like protein 3 1 SFDTVIGAGT(1)PPGLAEPLLVVRPK 107.87 7.7559e-07 1592800.0 12525.0 11273.0 12847.0 10315.0 20997.0 10833.0 12881.0 9504.4 9203.3 8813.4 True False 14645.235119973811 12392.108939338443 13153.321202518817 9737.083991681213 16882.788578225685 10264.898409593414 11660.818429635874 9254.919570744216 9337.880851566988 10411.199653163983 1.4066808444618673 1.1902671500082564 1.2633819003289883 0.9352509140214302 1.6215987725386645 0.9859477055051856 1.120026396390557 0.8889388234843454 0.8969072885591228 1.0 13.345848695444499 -6.9350586977247515 24.999982165513956 0.9794551016916871 1.2624001681921693 0.43674620516236984 0.17241260055259597 60.306713587908405 23215.209207982327 0.05906716082921421 0.05209233833914334 1.1612916471115675e-07 6.9350586977247515 0.2829450665004821 SFDYNY(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFDYNYR 7 0 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 1 S(0.375)FDY(0.021)NY(0.605)R 98.41799999999999 0.017644 76760000.0 33147.0 40717.0 35979.0 35835.0 36747.0 33648.0 44904.0 19533.0 30011.0 28351.0 True False 38758.13241690794 44759.11467072151 36836.87581111732 33827.28112863753 29546.689140546707 31883.439646081344 40650.36804319302 19020.27944692423 30449.85409976606 33490.8118736075 1.1572765856850238 1.336459529247603 1.099909908130555 1.0100466138683006 0.8822326927174625 0.9520055759295329 1.2137767276769909 0.5679253019815026 0.9092002372078095 1.0 15.031477729372229 -5.689527922465267 1.986996769218903 0.9165960157684476 1.2476875505945544 0.4027756855071477 0.15517187420791406 0.3265533036040253 2.612973187757829 0.0476790696815166 0.1018088332078274 2.0439585178107185e-06 5.689527922465267 0.33109153482610676 SFDYNY(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 SFDYNYR 7 0 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 1 S(0.273)FDY(0.024)NY(0.703)R 98.41799999999999 0.017644 297090000.0 27486.0 49443.0 33380.0 40307.0 36475.0 41729.0 39353.0 44251.0 39368.0 33975.0 True False 27094.04459968492 49328.51777126887 30635.625250526184 43271.31124021034 34329.612212609136 39944.34794505008 41390.505784292145 46307.06300621774 34933.9612765816 39847.53348115815 0.679942827891626 1.237931522024915 0.7688211182509501 1.0859219494895744 0.8615241449973772 1.002429622499413 1.0387219024199725 1.1621061320674708 0.8766906813215948 1.0 15.282202805280109 -6.986881171991432 24.11828770307448 1.0311295763933492 0.9429526327352741 0.06664617069532208 0.15987877765730682 444.8615099153683 817848.9265961209 0.052108878746976846 0.04592466395848413 1.0306680846104166e-07 6.986881171991432 -0.08817694365807516 SFELPPY(ph)TPPPILS(ph)PVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFELPPYTPPPILSPVR 17 0 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 2 S(0.07)FELPPY(0.577)T(0.354)PPPILS(1)PVR 137.91 3.3457999999999997e-07 0.0 9750.8 10773.0 10818.0 10580.0 10265.0 12450.0 12325.0 16354.0 13877.0 9599.5 True False 11401.417852921402 11842.472243723334 11075.942147493468 9987.236900822798 8253.646937919062 11797.100083027595 11157.486774727278 15924.72482849531 14079.92487229527 11339.813360399812 1.0054325843436474 1.044326909742525 0.9767305506254786 0.8807232168123333 0.727846806257141 1.040325771517959 0.9839215532145138 1.4043198351135688 1.2416363854333181 1.0 13.469109275011117 -7.643983238998485 7.003429195380608 1.240719326011723 0.9450511151374715 0.4761057665495694 0.12646082244856974 0.17518227899680408 9.987196949503113 0.061369963148174736 0.03509001886276887 2.2699524559035977e-08 7.643983238998485 -0.29566821087425155 SFENVSVES(ph)VDSSSEK ddPTM_PC-9_Lapatinib_30min_R1 2 SFENVSVESVDSSSEK 16 0 Q52LW3;F8VWZ8;Q52LW3-2 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 S(0.001)FENVS(0.285)VES(0.707)VDS(0.003)S(0.003)S(0.001)EK;SFENVSVES(0.999)VDSSSEK 137.81 1.4035999999999999e-05 5712600.0 35898.0 20029.3 31221.0 33627.0 28616.0 27181.0 22625.8 24530.0 35391.0 39946.0 True False 35386.08793711307 19982.923386446517 28654.129896545175 36100.04175638355 26932.863141220623 26018.5319920057 23797.25321511036 25669.75335116769 31404.892896248195 46850.612875300736 0.7552961586926931 0.4265242685220315 0.611606297932794 0.770535101695867 0.5748668264576622 0.5553509419664916 0.5079389949166723 0.547906457904643 0.6703197881282061 1.0 15.515780300141996 -8.673965154140273 4.044265349902562 0.9999771283701487 0.5904636320748424 0.6029562992489901 0.09853132686311665 0.7520371391083771 19.350044714806607 0.09531609739538695 0.024950254981698297 2.1185311099533713e-09 8.673965154140273 -0.4095134962953063 SFENVSVESVDS(ph)SSEK ddPTM_PC-9_AZD4547_30min_R2 1 SFENVSVESVDSSSEK 16 0 Q52LW3;F8VWZ8;Q52LW3-2 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 SFENVSVES(0.004)VDS(0.952)S(0.043)S(0.002)EK 185.85 1.3802e-38 0.0 14604.0 14355.0 12530.0 15023.0 14766.0 17133.0 14550.0 13346.0 16486.0 11218.0 True False 19247.768217929504 18994.97302267508 12363.844013043446 11559.679453036268 12715.995779713032 16061.670801564343 15844.921812915121 11283.682360570401 17357.416303163944 10825.261234493459 1.7780419152009643 1.7546895738783437 1.1421289283668712 1.0678430019039789 1.1746594843545173 1.4837213119980572 1.4636987939309112 1.0423473499758358 1.6034177769176154 1.0 13.40211421994355 -5.2524167815867955 24.156934602906002 1.2559185668004091 1.7663658956306258 0.5298241673741108 0.1954803368221134 316.91511182266663 848494.569623967 0.0498043561723066 0.12748156485118303 5.592206737596787e-06 5.2524167815867955 0.5104473288302167 SFENVSVESVDS(ph)SSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFENVSVESVDSSSEK 16 0 Q52LW3;F8VWZ8;Q52LW3-2 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 SFENVSVES(0.015)VDS(0.629)S(0.178)S(0.178)EK 90.42200000000001 0.01931 0.0 4882.6 5112.3 5484.1 4906.5 6057.6 4070.0 5432.0 3887.2 1859.1 3586.7 True False 5709.127744254225 5619.815357986331 5614.861742565068 4631.604712087624 4870.65676484545 3856.562035174484 4917.4416357256505 3785.16511882885 1886.2858204283446 4236.9403176984215 1.3474647543195797 1.3263853008529303 1.3252161516438723 1.0931484431679677 1.1495693589309925 0.9102233560064482 1.1606114948527029 0.8933723005295993 0.44519999787323117 1.0 12.0488070914458 -6.659158206722529 0.5896159926860527 0.779227805515852 1.3750825608857553 0.5895240754510078 0.16641704941401755 0.631263096068439 0.47976272607032755 0.13491466310076364 0.17187638966223207 2.1920062761089589e-07 6.659158206722529 0.5958547553699033 SFENVSVESVDS(ph)SSEK ddPTM_PC-9_Lapatinib_30min_R1 2 SFENVSVESVDSSSEK 16 0 Q52LW3;F8VWZ8;Q52LW3-2 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 SFENVSVESVDS(0.945)S(0.052)S(0.003)EK;SFENVS(0.001)VES(0.051)VDS(0.71)S(0.222)S(0.017)EK 228.08 1.3580999999999998e-92 3148800.0 24876.0 32552.0 25761.4 24651.0 30349.0 30811.0 31594.0 30267.0 27229.0 14597.9 True False 24521.263678300304 32476.627843988925 23643.39713387975 26463.916773325338 28563.931488429713 29493.285353949013 33229.782729370716 31673.31531511588 24162.183285918505 17121.127564520935 1.4322224740100773 1.8968743572291495 1.3809485996047663 1.5456877284277055 1.6683440609145976 1.7226251742359624 1.9408641518582432 1.8499549866534815 1.4112495333536512 1.0 14.063490097537034 -8.560622075721062 4.7146446874971195 1.000275237884494 1.6808342141473567 0.5845072291679114 0.17757536865061116 0.1550808452207504 12.455817242709372 0.1772426872638051 0.04617356423504171 2.750286419045969e-09 8.560622075721062 0.6805589762628628 SFENVSVESVDSS(ph)SEK ddPTM_PC-9_AZD4547_30min_R2 1 SFENVSVESVDSSSEK 16 0 Q52LW3;F8VWZ8;Q52LW3-2 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 SFENVSVESVDS(0.083)S(0.866)S(0.05)EK 104.78 0.0012050999999999997 3633500.0 5903.2 9547.2 7142.2 5754.0 6795.4 8962.9 7359.6 7254.1 9072.6 6486.7 True False 7780.294805812203 12633.145694328352 7047.489761369426 4427.504198413813 5851.976007142209 8402.448446118082 8014.590142565643 6133.145527634777 9552.159113920006 6259.602607397814 1.2429374983992088 2.0182025100759695 1.1258685580200347 0.7073139424507934 0.9348797957599005 1.3423293734633857 1.2803672445745558 0.9797979060821552 1.5260008842463795 1.0 12.611855354833615 -5.360443779481967 9.502321987019878 1.1037200036084964 1.6296029173426263 0.3556106411596298 0.27909665386711224 0.37469800701907746 33.20725187769257 0.07273097186036681 0.1516548331234856 4.360700107114589e-06 5.360443779481967 0.5258829137341299 SFETFSHR ddPTM_PC-9_AZD4547_30min_R2 4 SFETFSHR 8 0 P30838;A8MYB8;I3L3I9 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 0 ;;; 195.06 0.0012795 61686200.0 184098.0 215757.0 340783.0 446032.0 406178.0 347789.0 281593.0 410307.0 293667.0 314805.0 False True 242637.33452371813 285496.2308919056 336263.99475634325 343206.2135257054 349787.1958426304 326041.6988504795 306654.2314820761 346903.4810668781 309189.6380869375 303783.7727691851 0.7987172333529283 0.9398007941287425 1.1069188840835045 1.1297713844197776 1.1514347611595395 1.0732689764117387 1.0094490192373509 1.1419421054147465 1.0177951088976032 1.0 18.212685281832158 -4.982082554078876 2.628830407066928 1.0854974130500807 0.791287584633713 0.734756546432408 0.05343343616696129 0.16015376358512512 1.9361391027400947 0.014144767985672758 0.08594140699234899 1.042119316405254e-05 4.982082554078876 -0.2942098284163678 SFETFSHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SFETFSHR 8 0 P30838;A8MYB8;I3L3I9 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 0 ;;;;; 225.24 1.5438e-11 65424900.0 286918.0 298352.0 363568.0 408513.0 463238.0 380974.0 390667.0 289301.0 316785.0 321213.0 False True 335487.5505111894 327970.41482032335 372236.8399593179 385625.3410270146 372469.8392818077 360995.0527736028 353660.19357585226 281707.1552897473 321417.38132666046 379446.3741792919 0.8841501022030281 0.8643393036227942 0.9809998600314271 1.0162841636346829 0.9816139107599228 0.9513730459393698 0.9320426222039602 0.7424162528869971 0.8470693178235188 1.0 18.533536483470826 -7.55207175020683 24.93887535313015 0.8442914535437613 0.9484556068355174 0.1974724298026913 0.07253275189519881 263.0248682600487 224692.71550273278 0.0345182954589602 0.019929490791484903 2.8049701878610968e-08 7.55207175020683 0.1041641532917561 SFETFSHR ddPTM_PC-9_Lapatinib_30min_R1 4 SFETFSHR 8 0 P30838;A8MYB8;I3L3I9 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 0 ;;; 209.11 0.00016326 62277000.0 187742.0 222467.0 291801.0 225027.0 242607.0 287234.0 230565.0 251239.0 283818.0 206989.0 False True 185064.7646523336 221951.89132983136 267810.2481644332 241576.23624806688 228337.33324371354 274949.6713951576 242502.52753679047 262912.48113306204 251851.42810396326 242766.7728544946 0.7623150502694804 0.9142597593570232 1.10315857897468 0.9950959655951711 0.9405625430485517 1.1325671473169527 0.9989115260107588 1.0829837956887207 1.0374213288855376 1.0 17.88921144990848 -4.9319797934956755 3.0529708688977477 1.036249539500487 0.7562538732132402 0.7073100560085412 0.055118863310944115 0.15066191916406582 2.513940396395325 0.013968244537360763 0.0864162855730898 1.1695538058127108e-05 4.9319797934956755 -0.2799956662872467 SFEVEEVET(ph)PNSTPPRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFEVEEVETPNSTPPRR 17 1 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 SEPT9 Septin-9 1 S(0.031)FEVEEVET(0.878)PNS(0.037)T(0.053)PPRR 118.16 0.00039659 4716800.0 5557.5 4622.1 5682.9 7110.8 8217.9 7911.5 5485.2 6646.5 5123.0 5388.2 True False 6498.274984371609 5080.9515416052745 5818.401888518268 6712.404929524644 6607.661487688751 7496.607012600228 4965.602146591 6472.036417548862 5197.914183236198 6365.038007032268 1.0209326287120575 0.7982594190312298 0.9141189545278344 1.05457421025744 1.0381181511231237 1.1777788293357827 0.7801370771242633 1.016810333323757 0.8166352152953997 1.0 12.63595341346166 -4.388894350484916 21.336869537498675 0.9585301760660255 46.10618190922698 0.024917332754053167 0.12180408329804998 2651.309609798082 422318.32817663654 0.029708894847059415 1368.8127698468677 4.0841872904715237e-05 4.388894350484916 45.147651733160956 SFEVEEVETPNS(ph)TPPRR ddPTM_PC-9_AZD4547_30min_R2 1 SFEVEEVETPNSTPPRR 17 1 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 SEPT9 Septin-9 1 SFEVEEVET(0.014)PNS(0.743)T(0.243)PPRR 87.228 0.0013437000000000002 26410000.0 35201.0 35071.0 40268.0 51341.0 48522.0 52301.0 30751.0 61695.0 44047.0 49972.0 True False 46394.18577371515 46407.0148992154 39734.020009356194 39505.12566054285 41785.55785068641 49030.610202102194 33487.779427419446 52161.45536006225 46375.2344962673 48222.495490293004 0.9620859580577723 0.9623519983232088 0.8239727041366927 0.8192260740320889 0.86651587450711 1.0167580442196704 0.6944431035129736 1.0816830367180426 0.9616929614437405 1.0 15.557418691176608 SFEVEEVETPNS(ph)TPPRR ddPTM_PC-9_Lapatinib_30min_R1 1 SFEVEEVETPNSTPPRR 17 1 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 SEPT9 Septin-9 1 SFEVEEVET(0.112)PNS(0.444)T(0.444)PPRR 97.384 0.00066898 29577000.0 52847.0 39392.0 63307.0 48575.0 53434.0 46238.0 39000.0 51810.0 47708.0 49242.0 True False 52093.39208904713 39300.79024423727 58102.14283208692 52147.36754144982 50291.11717528598 44260.50852604244 41019.22917153444 54217.28174170391 42334.62265248818 57753.41408915939 0.9019967548347123 0.6804929347304894 1.006038235980113 0.9029313394519848 0.8707903760918244 0.7663704254386298 0.7102476938975276 0.9387718907492392 0.7330237237080431 1.0 15.817618613418604 -4.472895306318658 23.190480103467465 0.8412835142735582 1.777863126639284 0.02105832791911455 0.1126349340944789 367.83000603365747 1027746.4030402617 0.026364161242758973 120804.32623202018 3.365927006890986e-05 4.472895306318658 0.9365796123657257 SFEVEEVETPNST(ph)PPRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFEVEEVETPNSTPPRR 17 1 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 SEPT9 Septin-9 1 S(0.001)FEVEEVET(0.025)PNS(0.217)T(0.757)PPRR;S(0.025)FEVEEVET(0.077)PNS(0.38)T(0.518)PPRR 112.03 0.00097828 17192100.0 26051.2 25113.8 30631.9 38729.0 35467.8 35162.9 29672.2 32084.7 22222.5 24409.3 True False 30461.153625346244 27606.932092677893 31362.280668127652 36559.13969111212 28518.139197732664 33318.8956232523 26861.43440787529 31242.510621549678 22547.462021660434 28834.512866087527 1.056412978669455 0.957426685891635 1.087664661226618 1.2678951734298096 0.9890279516833124 1.1555213635129202 0.9315723325247229 1.0835109567012735 0.7819609135196683 1.0 14.815509029077612 -7.737693171605406 1.4756909327034933 0.9178921039231627 1.0812240011238572 0.2544547296743035 0.10863037554913407 0.5931131348943333 2.4171979104066597 0.08436182147858734 0.03341817881625043 1.8293922225269838e-08 7.737693171605406 0.16333189720069452 SFGDKDLILPNGGTPAGT(ph)SSPASSSSLLNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFGDKDLILPNGGTPAGTSSPASSSSLLNR 30 1 Q5VWJ9 Q5VWJ9 SNX30 Sorting nexin-30 1 SFGDKDLILPNGGTPAGT(0.383)S(0.383)S(0.146)PAS(0.056)S(0.022)S(0.008)S(0.001)LLNR 120.18 2.6173e-17 7645400.0 26342.0 25253.0 27677.0 33981.0 38091.0 36562.0 36385.0 33508.0 29736.0 27429.0 True False 30801.18032178445 27759.950948737143 28336.924645606996 32077.154737888417 30627.341988531407 34644.624356277505 32938.34939541197 32628.45050466071 30170.832745014948 32401.66057215547 0.9506049930124136 0.8567446994550889 0.8745516169612145 0.9899849011273849 0.94523988733007 1.0692237294174218 1.0165636209311355 1.006999330543575 0.9311508179596945 1.0 14.983780132098342 -5.770234332735868 20.927232804482127 0.996479894870068 0.8902448603744296 0.5417721451670994 0.0421492204337684 18.06462829078063 42985.339870543816 0.012054730858595432 0.018291750141588455 1.6973275764928274e-06 5.770234332735868 -0.10623503449563843 SFGDKDLILPNGGTPAGT(ph)SSPASSSSLLNR ddPTM_PC-9_Lapatinib_30min_R1 1 SFGDKDLILPNGGTPAGTSSPASSSSLLNR 30 1 Q5VWJ9 Q5VWJ9 SNX30 Sorting nexin-30 1 SFGDKDLILPNGGT(0.001)PAGT(0.401)S(0.401)S(0.143)PAS(0.035)S(0.013)S(0.005)S(0.002)LLNR 119.55 2.9472e-17 5792300.0 87219.0 64481.0 74758.0 61417.0 70263.0 71532.0 53770.0 58411.0 70326.0 52583.0 True False 85975.24106599418 64331.698206200854 68611.6858142251 65933.81106110597 66130.26848237297 68472.7431092364 56553.947501369425 61124.988299839206 62405.14531438925 61671.90148755669 1.3940747567730027 1.0431281775733932 1.1125274907904148 1.0691061807849265 1.0722917063894295 1.1102745570939123 0.9170131962410807 0.9911318903013256 1.011889431153351 1.0 15.912325708180562 -2.422225296254544 1.3058589481095004 1.0303852574572858 199.9999985099876 0.7662872409225683 0.05862162342183468 409.1000210360667 1.6820993559270432 0.01794771633018373 242767.7208223724 0.0037824631331846515 2.422225296254544 198.9696132525303 SFGDKDLILPNGGTPAGTS(ph)SPASSSSLLNR ddPTM_PC-9_AZD4547_30min_R2 1 SFGDKDLILPNGGTPAGTSSPASSSSLLNR 30 1 Q5VWJ9 Q5VWJ9 SNX30 Sorting nexin-30 1 SFGDKDLILPNGGT(0.001)PAGT(0.081)S(0.62)S(0.247)PAS(0.028)S(0.011)S(0.005)S(0.007)LLNR 107.21 2.1077e-15 7127500.0 38442.0 35940.0 52142.0 64567.0 66198.0 55709.0 43586.0 67956.0 41147.0 50792.0 True False 50665.75635672733 47556.9021549942 51450.5630110224 49682.07570020587 57007.55036065583 52225.507423355426 47465.06956272982 57454.96167352936 43321.94641673459 49013.787539881574 1.0337041657003467 0.9702760088943966 1.0497161226146432 1.0136346973753154 1.1630921261547045 1.0655268659019779 0.9684024015509597 1.1722204007755852 0.8838726528017112 1.0 15.580900014847892 -5.291286989301744 22.499715295410084 1.0475811710931373 1.0019900825547532 0.02510215236542468 0.08228121247714694 599.5003555370741 451914.36910192197 0.020421159609070465 0.04252832701339618 5.113438190332805e-06 5.291286989301744 -0.04559108853838412 SFGDKDLILPNGGTPAGTS(ph)SPASSSSLLNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFGDKDLILPNGGTPAGTSSPASSSSLLNR 30 1 Q5VWJ9 Q5VWJ9 SNX30 Sorting nexin-30 1 SFGDKDLILPNGGTPAGT(0.02)S(0.432)S(0.432)PAS(0.059)S(0.02)S(0.028)S(0.009)LLNR 123.19 6.827899999999999e-18 5735900.0 35242.0 31778.0 35425.0 41905.0 48971.0 45845.0 43233.0 39008.0 40154.0 34732.0 True False 41207.774538771795 34932.70982651442 36269.66635006063 39557.198707843025 39375.484091264916 43440.807494489985 39137.65726018535 37984.08133239241 40741.17628609528 41028.636661639284 1.0043661669435875 0.8514226323092915 0.8840085681904178 0.9641363185930081 0.959707348211255 1.0587923711124922 0.9539107424638861 0.9257943822419658 0.9929936649390846 1.0 15.324343595340453 -5.888524468785045 5.069442824147623 0.9790640415126024 0.9074688263225573 0.2783454154798273 0.04894973632894706 0.26513953382914734 10.71017118278802 0.014087603551383245 0.021324951035308487 1.2926338698760115e-06 5.888524468785045 -0.07159521519004508 SFGDKDLILPNGGTPAGTS(ph)SPASSSSLLNR ddPTM_PC-9_Lapatinib_30min_R1 1 SFGDKDLILPNGGTPAGTSSPASSSSLLNR 30 1 Q5VWJ9 Q5VWJ9 SNX30 Sorting nexin-30 1 SFGDKDLILPNGGTPAGT(0.204)S(0.574)S(0.204)PAS(0.01)S(0.004)S(0.004)S(0.001)LLNR 163.27 7.525499999999999e-18 6667700.0 56614.0 45271.0 57053.0 46356.0 50057.0 53419.0 42065.0 48156.0 53328.0 37429.0 True False 55806.67397826395 45166.17778094193 52362.322570948796 49765.17487908278 47112.745675848535 51134.39389577107 44242.91987437424 50393.503562121085 47321.639071264544 43898.552778992474 1.2712645507751241 1.0288762367254183 1.19280293440577 1.1336404443587433 1.073218652857144 1.1648309718365315 1.0078446115778688 1.1479536424771786 1.0779772014240565 1.0 15.421885758194216 -1.52288001428134 0.03508599411625254 0.6452899283398278 1.825702548942719 0.3269480740903553 0.06832646242743151 1259.563668355602 3.3901080898441474 33.70207862036817 94.62744580168729 0.02999991234064434 1.52288001428134 1.1804126206028913 SFGDKDLILPNGGTPAGTSS(ph)PASSSSLLNR ddPTM_PC-9_AZD4547_30min_R2 1 SFGDKDLILPNGGTPAGTSSPASSSSLLNR 30 1 Q5VWJ9 Q5VWJ9 SNX30 Sorting nexin-30 1 SFGDKDLILPNGGT(0.001)PAGT(0.054)S(0.283)S(0.384)PAS(0.137)S(0.05)S(0.067)S(0.024)LLNR 90.833 2.0422000000000002e-09 7604400.0 39025.0 42746.0 61997.0 78713.0 82711.0 67843.0 48808.0 75204.0 59319.0 66261.0 True False 51434.138229574004 56562.808556410186 61174.87927187983 60566.93395372727 71228.00534578368 63600.7664851766 53151.81744637534 63582.949816000015 62454.481237861306 63941.22255827873 0.8043971662051779 0.8846063039357194 0.9567361527396894 0.9472282751322749 1.1139606422267492 0.9946754838353017 0.8312605752561351 0.9943968424758821 0.9767483125762517 1.0 15.964458708308234 -4.975369791309359 1.5961274658616162 0.9788554552586362 0.7757830357319829 0.43113820747348663 0.06474633933283556 0.7415962364762863 2.4145923070757074 0.019812231913542748 0.21064093250004665 1.0583521799750223e-05 4.975369791309359 -0.20307241952665323 SFGPVQS(ph)MTFVLETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFGPVQSMTFVLETR 15 0 H3BQP3;Q96IC2-2;Q96IC2 H3BQP3 LOC81691;44M2.3 Putative RNA exonuclease NEF-sp 1 SFGPVQS(0.951)MT(0.042)FVLET(0.007)R 57.106 0.024998 12813000.0 69014.0 42447.0 42972.0 46613.0 41292.0 30714.0 34669.0 49626.0 29854.0 37790.0 True False 80696.70711136698 46660.85763754983 43996.61545221753 44001.424731385 33201.129017102205 29103.303771093157 31384.901338176103 48323.37008309335 30290.558271780857 44641.02785452461 1.8076803109090582 1.0452460411442004 0.985564570681323 0.985672302949118 0.7437357653434292 0.6519407184336007 0.7030505982176903 1.082487845946753 0.6785363090314853 1.0 15.446082624986122 -2.1127225538794665 0.9572702835226597 0.8207763778041314 199.99993160627966 0.7999710470038952 0.1435343280109128 148.48492283277702 0.9016731991413174 0.046947968032072115 63935.17753021024 0.0077139611292591235 2.1127225538794665 199.17915522847554 SFGPVQS(ph)MTFVLETR ddPTM_PC-9_Lapatinib_30min_R1 2 SFGPVQSMTFVLETR 15 0 H3BQP3;Q96IC2-2;Q96IC2 H3BQP3 LOC81691;44M2.3 Putative RNA exonuclease NEF-sp 1 S(0.007)FGPVQS(0.992)MT(0.001)FVLETR;S(0.011)FGPVQS(0.984)MT(0.005)FVLETR 53.376999999999995 0.031389 24332000.0 126957.0 133186.0 86750.0 102990.0 103769.0 78465.0 94060.0 85366.0 72117.0 84447.0 True False 125146.56989893752 132877.61599992347 79617.74986468395 110564.22816456822 97665.51143770358 75109.23486084864 98929.96656088532 89332.41600390474 63994.42403432318 99043.55143144564 1.2635509136156073 1.341607950032936 0.803866064110115 1.1163193016265858 0.9860865248284651 0.7583455336093893 0.9988531825755569 0.9019508560911955 0.6461240849043848 1.0 16.595775426135894 -4.642780384166004 0.6208539728969946 0.8646974830259776 1.7156981256772712 0.4921199555248954 0.1474748340356024 3.3758105028481795 0.8728795424445509 0.06989786688160586 2.133563638909056 2.276248202411345e-05 4.642780384166004 0.8510006426512936 SFGT(ph)RPLSSGFSPEEAQQQDEEFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFGTRPLSSGFSPEEAQQQDEEFEK 25 1 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 S(0.076)FGT(0.326)RPLS(0.264)S(0.264)GFS(0.069)PEEAQQQDEEFEK 51.857 0.01261 5804800.0 4508.3 4291.7 6450.9 5249.3 7096.1 9274.1 6745.5 8572.1 8025.5 6148.0 True False 5271.466147016202 4717.7516131428 6604.713921174485 4955.19873946022 5705.670144780075 8787.749869880025 6106.517406809159 8347.091457890709 8142.85775474567 7262.583732458779 0.7258389494989718 0.6495968634492542 0.9094165608936023 0.6822914436516405 0.7856253855332 1.2100032431440062 0.840818864437625 1.1493280856212262 1.1212067295489714 1.0 12.82626717652957 -6.6594589625919065 6.937832011858859 1.0588049670908155 0.7462069824505317 0.6605591130624651 0.1126352594473379 0.13622179811425195 8.12115822548603 0.036248088178189614 0.03616001051968056 2.1904888022293948e-07 6.6594589625919065 -0.31259798464028377 SFGTRPLS(ph)SGFSPEEAQQQDEEFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFGTRPLSSGFSPEEAQQQDEEFEK 25 1 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 S(0.01)FGT(0.01)RPLS(0.404)S(0.404)GFS(0.17)PEEAQQQDEEFEK 54.985 0.003064 5313700.0 6004.4 6311.0 10252.0 9046.1 11183.0 12167.0 10846.0 9130.7 11929.0 9657.2 True False 7020.82632769427 6937.514372054017 10496.446560926515 8539.276344851902 8991.771427837202 11528.941101220626 9818.588361760008 8891.028799776335 12103.43905754921 11407.973913646867 0.6154314851032012 0.6081285269906664 0.9200973494837738 0.748535753104829 0.7882005600556935 1.0106037398480594 0.8606776659976804 0.7793696643310501 1.0609630727740698 1.0 13.477754967469894 -3.792682464205813 0.33179601351092075 0.9610752986578226 8.285973488028548e-13 0.5764250484711146 0.09854968367017973 10.42157723494025 0.5539923144729191 0.09553016386120672 4.562169431584396 0.0001611823694484676 3.792682464205813 -0.961075298656994 SFGTRPLS(ph)SGFSPEEAQQQDEEFEK ddPTM_PC-9_Lapatinib_30min_R1 1 SFGTRPLSSGFSPEEAQQQDEEFEK 25 1 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 S(0.001)FGT(0.005)RPLS(0.475)S(0.475)GFS(0.044)PEEAQQQDEEFEK 79.82 4.0765e-05 84728000.0 149840.0 147410.0 170770.0 122460.0 162660.0 181210.0 160480.0 165510.0 159880.0 92430.0 True False 147703.254122709 147068.68120184354 156729.94979126338 131466.1169145847 153092.65860186418 173460.07072114188 168788.8691653294 173200.19882396108 141872.63078896218 108406.40234476673 1.3624956730227595 1.356642025017291 1.4457628553414443 1.212715430740712 1.4122104902529742 1.6000906493463722 1.5570009290459368 1.5976934487054513 1.3087108115419441 1.0 16.726090437385864 -8.53975177145578 21.72385043411802 0.9999999938451161 1.4413956804965053 0.5828397761500627 0.11382071779051484 410.86861994900875 528990.0858222422 0.122092173126915 0.031524063564931024 2.88568039253819e-09 8.53975177145578 0.4413956866513893 SFGTRPLS(ph)SGFSPEEAQQQDEEFEKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFGTRPLSSGFSPEEAQQQDEEFEKK 26 2 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 S(0.014)FGT(0.017)RPLS(0.323)S(0.323)GFS(0.323)PEEAQQQDEEFEKK 40.402 0.029102999999999997 9718800.0 0.0 3556.9 0.0 7986.3 2472.1 5550.3 5914.4 6698.0 6515.1 2346.0 True False 0.0 3910.0055252668253 0.0 7538.853502933947 1987.7097511183358 5259.2324972552715 5354.14521545209 6522.184597117627 6610.371012141739 2771.311229074219 0.0 1.4108864728892239 0.0 2.7203200506109764 0.7172452268316134 1.8977415607745234 1.931989867930023 2.3534652220553447 2.385286409837841 1.0 11.436353024867307 -5.411779680579936 0.6726352095907618 1.9844539251628135 2.840614586171685e-15 0.3327586415977002 0.761151065608156 1.849480174672112 1.0898664842304402 0.36823222095861996 2.4975852740004867 3.874541521964155e-06 5.411779680579936 -1.9844539251628106 SFGTRPLSS(ph)GFSPEEAQQQDEEFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFGTRPLSSGFSPEEAQQQDEEFEK 25 1 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 S(0.037)FGT(0.007)RPLS(0.164)S(0.569)GFS(0.223)PEEAQQQDEEFEK 70.461 0.00022006 113820000.0 26020.0 29457.0 35913.0 53889.0 62327.0 51568.0 47261.0 56387.0 50381.0 46215.0 True False 30424.672081574332 32381.296285469067 36769.302120810935 50869.774040495235 50114.47176811312 48863.683299724275 42784.09593999076 54906.90099696497 51117.726813512156 54593.41366226132 0.5572956523619246 0.5931355838232409 0.6735116867445198 0.9317932444231799 0.9179582005650555 0.8950472231323789 0.7836860359139995 1.0057422189541585 0.9363350518754646 1.0 15.736439289486668 -5.6463906100731 3.1851550525344794 0.9185058285525232 0.5822576806238456 0.8588479415130843 0.05946606774010415 0.08822601644067089 1.7649007368474086 0.017444637997730775 0.03290643573161125 2.257404518075517e-06 5.6463906100731 -0.3362481479286775 SFGTRPLSS(ph)GFSPEEAQQQDEEFEK ddPTM_PC-9_Lapatinib_30min_R1 1 SFGTRPLSSGFSPEEAQQQDEEFEK 25 1 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 S(0.116)FGT(0.037)RPLS(0.1)S(0.374)GFS(0.374)PEEAQQQDEEFEK 73.389 0.00011334 156290000.0 32353.0 32840.0 27156.0 26831.0 31296.0 28889.0 24503.0 20240.0 32845.0 23081.0 True False 31891.640287186445 32763.96099768358 24923.338505191416 28804.24124559215 29455.230810303347 27653.48481354817 25771.645445900194 21180.4242897527 29145.650226816746 27070.52009650069 1.178094849064572 1.210318859072045 0.9206819232266308 1.0640446191248305 1.08809253406664 1.02153503940705 0.9520188512828611 0.782416599838088 1.0766564559128768 1.0 14.724434985367353 -2.592902254881631 0.3839766704495619 0.949752468583767 2.614793496659224 0.370732994424506 0.09434651719557821 31.12708158744375 0.9224018381222062 0.07426595937675172 33.79180355360611 0.002553275894745927 2.592902254881631 1.665041028075457 SFGTRPLSSGFS(ph)PEEAQQQDEEFEK ddPTM_PC-9_AZD4547_30min_R2 4 SFGTRPLSSGFSPEEAQQQDEEFEK 25 1 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 S(0.007)FGT(0.006)RPLS(0.029)S(0.029)GFS(0.929)PEEAQQQDEEFEK;S(0.036)FGT(0.033)RPLS(0.261)S(0.261)GFS(0.409)PEEAQQQDEEFEK;S(0.07)FGT(0.015)RPLS(0.281)S(0.281)GFS(0.353)PEEAQQQDEEFEK;S(0.011)FGT(0.01)RPLS(0.185)S(0.185)GFS(0.61)PEEAQQQDEEFEK 87.61 3.9225999999999995e-06 273056100.0 47218.5 50528.899999999994 74458.0 95013.0 90762.0 78419.0 62789.0 83039.0 62284.3 74459.0 True False 62233.000794186766 66861.37877850559 73470.63827000705 73109.22078621684 78161.2629661595 73515.4475332911 68377.09936158957 70207.23059638872 65576.52094208144 71852.21307355569 0.8661250382152926 0.9305402842645788 1.022524361146602 1.0174943492885091 1.0878059230568888 1.023147992088048 0.9516352584935887 0.9771060290727165 0.9126583321094122 1.0 16.132744972433507 -4.998451980789145 3.0548830010434367 1.0010133397968761 0.8676103898677074 0.47729872246685523 0.0444780722562644 0.25269307751227693 4.503672033206768 0.01283301765706854 0.0639240904534186 1.003570806150687e-05 4.998451980789145 -0.13340294992916868 SFGTRPLSSGFS(ph)PEEAQQQDEEFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SFGTRPLSSGFSPEEAQQQDEEFEK 25 1 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 S(0.033)FGT(0.099)RPLS(0.268)S(0.268)GFS(0.333)PEEAQQQDEEFEK;S(0.01)FGT(0.008)RPLS(0.268)S(0.268)GFS(0.445)PEEAQQQDEEFEK;S(0.002)FGT(0.003)RPLS(0.187)S(0.187)GFS(0.62)PEEAQQQDEEFEK;S(0.008)FGT(0.008)RPLS(0.093)S(0.403)GFS(0.489)PEEAQQQDEEFEK;S(0.008)FGT(0.007)RPLS(0.086)S(0.086)GFS(0.813)PEEAQQQDEEFEK 73.685 0.00010256 321640800.0 177574.0 195202.0 248547.0 324653.0 397731.0 362535.0 382040.0 342040.0 310107.0 275559.0 True False 207633.77095363123 214580.36451492485 254473.30309974676 306463.7449492266 319798.46568587364 343523.02639360755 345850.4054699235 333061.8124213366 314641.72821019473 325515.66537615645 0.6378610710292412 0.6592013452469699 0.7817543982274548 0.9414715712532176 0.9824364837136911 1.0553194912958868 1.0624693133286498 1.023182131761493 0.9665947346853612 1.0 18.312367448908113 -5.647739181322953 1.4371075826640913 1.0238578873446813 0.6265702718225902 0.9677588359672442 0.02711931235605557 0.07332473138858019 0.2959993317963455 0.009473808154070716 0.026055228730267 2.250405697430717e-06 5.647739181322953 -0.39728761552209113 SFGTRPLSSGFS(ph)PEEAQQQDEEFEK ddPTM_PC-9_Lapatinib_30min_R1 1 SFGTRPLSSGFSPEEAQQQDEEFEK 25 1 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 SFGTRPLS(0.009)S(0.009)GFS(0.981)PEEAQQQDEEFEK 82.26700000000001 1.9726e-05 154580000.0 46978.0 35845.0 57683.0 48387.0 54466.0 48673.0 42859.0 44600.0 50651.0 34323.0 True False 46308.08510528993 35762.00310481025 52940.52640281913 51945.54139430015 51262.41696427601 46591.36925230468 45078.02930930242 46672.27882030489 44946.15100132428 40255.684817477275 1.1503489585447313 0.8883714999995214 1.31510683876963 1.2903902052548772 1.2734205664790998 1.1573860800916427 1.1197928817678813 1.1593959718216447 1.116516864763672 1.0 15.296904911319805 -8.789351265198729 0.928230912638814 1.0002480227225157 1.175593463676007 0.17486382088485242 0.11317965254918798 1.9266514539931516 3.1795025896327913 0.11814489020217145 0.039322342597505236 1.6242345142030076e-09 8.789351265198729 0.17534544095349136 SFHFDPLS(ph)SGSR ddPTM_PC-9_AZD4547_30min_R2 1 SFHFDPLSSGSR 12 0 Q9C0B5;Q9C0B5-2;H0YEF4 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5;Palmitoyltransferase 1 SFHFDPLS(0.552)S(0.175)GS(0.273)R 64.22399999999999 0.044506 2141200.0 10588.0 13423.0 23899.0 28520.0 21959.0 18227.0 16098.0 32534.0 16652.0 18986.0 True False 13954.763755918764 17761.72224892841 23582.083644670813 21945.154629607572 18910.37188993082 17087.262808621563 17530.69081404177 27506.6178569457 17532.19072426822 18321.305918888633 0.7616686178211721 0.969457217054418 1.287139887793615 1.1977942362166922 1.0321519641476473 0.9326443695809471 0.9568472297582364 1.5013459181742788 0.9569290967514024 1.0 14.161234720078017 -4.924117366370114 3.826926735670211 1.115907618571769 0.7689751276281155 0.28060747981602596 0.1705693199003287 0.30034388430273573 8.138075553565876 0.04387923200991668 0.2286196472898092 1.1909201230710862e-05 4.924117366370114 -0.3469324909436534 SFIS(ph)PASIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFISPASIR 9 0 C9IYV0;Q8N8L2 C9IYV0 ZNF491 Zinc finger protein 491 1 SFIS(0.838)PAS(0.162)IR 78.516 0.016915 0.0 21820.0 23581.0 22391.0 24138.0 23685.0 16771.0 22574.0 16647.0 19401.0 16414.0 True False 25513.69503535558 25921.965838600172 22924.886358340376 22785.626116451866 19044.094274195126 15891.49923634184 20435.627298392992 16210.033888954471 19684.70292191401 19389.7282668475 1.315835615859497 1.3368916511801494 1.182321177627707 1.1751390118968639 0.9821743766650232 0.8195833906302379 1.053940881334256 0.8360114007719406 1.0152129339311502 1.0 14.243004964798253 -5.982008798651602 1.4472505209819768 0.9360571605365076 1.3147693304301173 0.7953390752136893 0.07685908092096613 0.16703108783288748 0.7091419747671297 0.025881577853642392 0.04675292581638416 1.042296312627141e-06 5.982008798651602 0.3787121698936098 SFLEDIR ddPTM_PC-9_Lapatinib_30min_R1 1 SFLEDIR 7 0 P52209-2;P52209;K7ELN9 P52209-2 PGD 6-phosphogluconate dehydrogenase, decarboxylating 0 108.09 0.045207 2159000.0 28464.0 29444.0 30505.0 30062.0 30500.0 31931.0 29746.0 31608.0 29939.0 29414.0 False True 28058.098140341688 29375.824227033954 27996.99665270528 32272.85976389222 28706.04996530715 30565.385564796525 31286.102331704198 33076.623070677044 26566.954548353384 34498.17070830862 0.8133213316607569 0.8515183160120142 0.811550180136433 0.9354948132400407 0.8321035398666375 0.8860001831179728 0.9068916319139547 0.9587935357601669 0.7700974864141111 1.0 15.074232243468643 -14.522878745280336 0.10261276843843657 1.3792680636678167 0.7886197152651212 0.32852355429073243 0.05715261309950494 212.69429944234588 1.4707955294999107 17.623681871012238 0.85827530509197 3.0000000000000132e-15 14.522878745280336 -0.5906483484026955 SFLEDIRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFLEDIRK 8 1 P52209-2;P52209;K7ELN9 P52209-2 PGD 6-phosphogluconate dehydrogenase, decarboxylating 0 86.833 0.0077068 5439700.0 34688.0 34749.0 41086.0 46778.0 47599.0 35653.0 41680.0 42709.0 41118.0 38509.0 False True 40559.993280770555 38198.65107185948 42065.64605952268 44157.1803163222 38272.31764228053 33783.29391648055 37731.76866293172 41587.93400392601 41719.27296238645 45490.376862923746 0.8916169985355381 0.8397083890283776 0.9247152686001961 0.9706927785931765 0.84132777702868 0.742647044193101 0.8294450665165721 0.9142138815258231 0.9171010626730842 1.0 15.473273766168884 -8.502908293312176 1.6492746381108205 0.9971157176730441 0.8650404473958678 0.3273050364059872 0.05876546325091029 0.5102771727557619 3.0870788897828407 0.06278885456778015 0.01820513015856789 3.141171921415434e-09 8.502908293312176 -0.13207527027717625 SFLEDIRK ddPTM_PC-9_Lapatinib_30min_R1 1 SFLEDIRK 8 1 P52209-2;P52209;K7ELN9 P52209-2 PGD 6-phosphogluconate dehydrogenase, decarboxylating 0 79.71300000000001 0.012861000000000001 11074000.0 67320.0 80515.0 83491.0 88305.0 89811.0 80634.0 71410.0 53054.0 73260.0 68986.0 False True 66360.00445502413 80328.57246432701 76626.69226457996 94799.24427684468 84528.49355521973 77185.47178703456 75107.2603881866 55519.08252314922 65008.687337999625 80910.13818193317 0.8201692142189665 0.9928122021458119 0.9470592188617757 1.171660887090326 1.044720667330346 0.9539653932301613 0.9282799668355735 0.6861820257717265 0.8034677581667478 1.0 16.304032865744993 -7.557188863963681 6.57326151884311 0.8069917344613151 0.9933205513550877 0.2878001914108169 0.10956707575993736 0.20495083337815828 26.227913819293168 0.05247210964261708 0.030375604519675973 2.7721143183103258e-08 7.557188863963681 0.18632881689377256 SFLSEPSS(ph)PGR ddPTM_PC-9_AZD4547_30min_R2 6 SFLSEPSSPGR 11 0 H0YC41;Q69YN4-3;Q69YN4 H0YC41 KIAA1429 Protein virilizer homolog 1 SFLSEPS(0.002)S(0.998)PGR;SFLSEPS(0.013)S(0.987)PGR;SFLSEPS(0.024)S(0.976)PGR;SFLSEPS(0.002)S(0.998)PGR;SFLSEPS(0.001)S(0.999)PGR;SFLSEPS(0.002)S(0.998)PGR 202.65 1.4019e-05 288628700.0 589325.0 528129.0 785246.0 1002814.0 819451.0 780572.0 623306.0 822744.0 609891.0 692061.0 True False 776718.091278507 698836.3711245119 774833.1249693783 771630.725621855 705684.3734038754 731762.7094448557 678779.0264962806 695607.8195762872 642128.5931428467 667832.1550369732 1.1630438657681967 1.0464251621514424 1.1602213507172041 1.1554261348484114 1.0566792390594109 1.095728475973642 1.0163916507714448 1.0415907864421057 0.9615119432326473 1.0 19.34912603294051 -7.225025579831705 0.9340175444398062 0.9886540084682918 1.124921657700693 0.658295903809884 0.03957722063493227 0.36342078367570835 0.6219278940960695 0.02903005720604801 0.017235462662710217 5.956270602173352e-08 7.225025579831705 0.1362676492324013 SFLSEPSS(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SFLSEPSSPGR 11 0 H0YC41;Q69YN4-3;Q69YN4 H0YC41 KIAA1429 Protein virilizer homolog 1 SFLSEPS(0.004)S(0.996)PGR;SFLSEPS(0.167)S(0.833)PGR;SFLSEPS(0.041)S(0.959)PGR;SFLSEPS(0.004)S(0.996)PGR;SFLSEPS(0.004)S(0.996)PGR;SFLSEPS(0.025)S(0.975)PGR 174.23 6.476399999999999e-05 171308600.0 336033.0 317064.0 368552.0 395624.0 416370.0 367339.0 405503.0 357417.0 352302.0 300665.0 True False 392916.74994572107 348540.01851702377 377339.6774212436 373458.4699103129 334785.2874370543 348075.0961766485 367090.82025251474 348035.1824646154 357453.7502600972 355173.18443716917 1.1062680606599364 0.9813241364754022 1.062410378810554 1.0514827308883687 0.9425973077544612 0.9800151346679824 1.0335544358007518 0.9799027564992973 1.006420996637294 1.0 18.43816313681205 -6.224751538067548 24.935962414314073 0.9910472019082938 1.0462993325278502 0.40031583639633417 0.035806602762468547 627.0801016430653 426213.16303981026 0.010323588308767152 0.013327239725185786 5.960030221657027e-07 6.224751538067548 0.05525213061955647 SFLSEPSS(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 6 SFLSEPSSPGR 11 0 H0YC41;Q69YN4-3;Q69YN4 H0YC41 KIAA1429 Protein virilizer homolog 1 SFLSEPS(0.002)S(0.998)PGR;SFLSEPS(0.002)S(0.998)PGR;SFLSEPSS(1)PGR;SFLSEPS(0.002)S(0.998)PGR;SFLSEPSS(1)PGR;SFLSEPSS(1)PGR 202.65 1.4019e-05 284660300.0 1348916.0 1162811.0 1317992.0 1153572.0 1147122.0 1176480.0 977946.0 1107140.0 1332478.0 927935.0 True False 1329680.2104791047 1160118.5825723931 1209631.785356247 1238409.5330833818 1079650.5392886256 1126164.6929088295 1028579.2587534727 1158581.766213279 1182400.2960246096 1088327.328354332 1.221764974412362 1.0659647629418783 1.1114595341323834 1.1379017146945951 0.9920274086300612 1.0347665298561526 0.9451010113922208 1.0645526727378787 1.0864381195063126 1.0 20.053681100150534 -1.5228787458046666 0.43895669876044036 1.0212070983626915 4.7660675037108104 0.5274086350343737 0.05205566121406801 72.61367487231873 0.8959810650135054 0.03494326606437921 241.96633513256404 0.02999999996378063 1.5228787458046666 3.7448604053481187 SFLVASVLPGPDGNINS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 2 SFLVASVLPGPDGNINSPTR 20 0 Q7Z3K3-5;Q7Z3K3-7;Q7Z3K3-2;Q7Z3K3-3;Q7Z3K3-6;Q7Z3K3 Q7Z3K3-5 POGZ Pogo transposable element with ZNF domain 1 SFLVASVLPGPDGNINS(0.936)PT(0.064)R;SFLVAS(0.238)VLPGPDGNINS(0.661)PT(0.102)R 160.47 7.2775999999999996e-06 14271100.0 35259.0 37337.0 52052.0 72665.0 55172.0 51765.0 45038.0 62721.0 44543.0 53298.0 True False 46470.628567240194 49405.45508517024 51361.75646982737 55913.20691305868 47512.32013804191 48528.126366834644 49046.29474983309 53028.91063519677 46897.452043663216 51432.0532426486 0.9035343844430794 0.9605965924028508 0.998633210840532 1.087127644880687 0.9237881271021013 0.9435385777403504 0.9536133919919575 1.0310479028518351 0.9118331679742236 1.0 15.65038012888163 -5.895518466521793 0.002395877518238965 1.9418328602816979 1.2161285361275827e-05 0.014754905934325047 0.0544938661322182 628499.6688758467 360.34697437701215 144395.34955399166 147664.84968460834 1.2719836632519622e-06 5.895518466521793 -1.9418206989963367 SFLVASVLPGPDGNINS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFLVASVLPGPDGNINSPTR 20 0 Q7Z3K3-5;Q7Z3K3-7;Q7Z3K3-2;Q7Z3K3-3;Q7Z3K3-6;Q7Z3K3 Q7Z3K3-5 POGZ Pogo transposable element with ZNF domain 1 SFLVASVLPGPDGNINS(0.979)PT(0.021)R;SFLVASVLPGPDGNINS(0.909)PT(0.091)R 184.88 1.6830999999999997e-11 10702600.0 50367.0 51775.0 59292.0 63039.0 63467.0 59922.0 64116.0 63028.0 56554.0 43184.0 True False 58893.13830640484 56914.87983094548 60705.74614616218 59507.12920519553 51031.09695167164 56779.58483334776 58042.46832035822 61373.5817836861 57380.99526034354 51012.91735564408 1.1544750106296144 1.1156954509022685 1.190007341139561 1.166510999367725 1.0003563724046758 1.113043279558009 1.1377994305972854 1.2030988417269124 1.1248326548411938 1.0 15.638574988305649 -11.912853825051036 2.0896871907753733 0.1272434477453277 1.133646178122551 0.3648557947280898 0.0530301776729534 756596.0477271833 141484.5950416543 3094447.3266694793 0.014189196902956192 1.2222109630245982e-12 11.912853825051036 1.0064027303772234 SFLVASVLPGPDGNINS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 2 SFLVASVLPGPDGNINSPTR 20 0 Q7Z3K3-5;Q7Z3K3-7;Q7Z3K3-2;Q7Z3K3-3;Q7Z3K3-6;Q7Z3K3 Q7Z3K3-5 POGZ Pogo transposable element with ZNF domain 1 SFLVASVLPGPDGNINS(0.963)PT(0.037)R;SFLVASVLPGPDGNINS(0.676)PT(0.324)R 216.31 1.8960999999999998e-28 9665600.0 46615.0 42145.0 45273.0 37804.0 43849.0 42068.0 36917.0 37406.0 44572.0 33242.0 True False 45950.26155185596 42047.41584188106 41550.82869883383 40584.23227044711 41269.88803045091 40268.84970529769 38828.38162373171 39144.01931731668 39551.83199603217 38987.83540781926 1.1785794484666452 1.078475257783821 1.0657382812922347 1.0409460244696653 1.0585324268136715 1.0328567688890344 0.9959101657627402 1.0040059651392212 1.0144659630962687 1.0 15.25073643854012 -1.5228787452803405 0.4275708155650558 1.006796179397515 4.125607362438489 0.9054775770640641 0.015901399026687826 24.11438189075094 0.30453356157019107 0.011232990972712128 64.67679051399676 0.029999999999999798 1.5228787452803405 3.1188111830409735 SFLVIVDGS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 SFLVIVDGSPK 11 0 Q9H116-4;Q9H116 Q9H116-4 GZF1 GDNF-inducible zinc finger protein 1 1 SFLVIVDGS(1)PK 86.911 0.029918 0.0 14001.0 13094.0 14479.0 13526.0 13659.0 14590.0 13215.0 10543.0 8830.0 12401.0 True False 18453.026761108667 17326.379432874084 14286.99899958947 10407.789674616834 11762.683621502112 13677.684993569355 14391.109399152809 8913.8216040382 9296.735773197726 11966.844764570638 1.5420127129701886 1.4478653123479155 1.1938818695039768 0.8697187838042668 0.9829394341545258 1.1429650223310222 1.202581773414452 0.7448765133503443 0.7768744356676115 1.0 13.546755194106497 -5.393608040741788 2.4155315574661738 0.9682534870304476 1.519765753567674 0.7052871318055248 0.13775508870442021 0.1817527210202649 2.024450726262976 0.04274726512205986 0.11779499958795592 4.040098552664503e-06 5.393608040741788 0.5515122665372265 SFMALSQDIQK ddPTM_PC-9_Lapatinib_30min_R1 1 SFMALSQDIQK 11 0 G3V153;Q14444-2;Q14444;E9PLA9 G3V153 CAPRIN1 Caprin-1 0 113.63 0.0039585 0.0 12118.0 10320.0 11313.0 11584.0 11791.0 10852.0 13762.0 8884.4 9993.4 8987.4 False True 11945.19509783096 10296.104674058904 10382.888809442866 12435.926003091188 11097.476561997923 10387.885257247564 14474.529022016837 9297.201658096783 8867.838056832712 10540.860115042253 1.1332277411389475 0.9767803159977361 0.9850134330713719 1.1797828514339732 1.0528056003856228 0.985487440671337 1.3731829152500632 0.8820154671087308 0.8412822065798912 1.0 13.363704972623035 SFPIKPVPS(ph)PSWSGSCR ddPTM_PC-9_AZD4547_30min_R2 1 SFPIKPVPSPSWSGSCR 17 1 Q9P0U3;Q9P0U3-2 Q9P0U3 SENP1 Sentrin-specific protease 1 1 SFPIKPVPS(0.865)PS(0.1)WS(0.01)GS(0.025)CR 78.418 0.0033249000000000004 20869000.0 38182.0 40713.0 52756.0 59277.0 58434.0 49382.0 35374.0 57851.0 47330.0 49486.0 True False 50323.081765063274 53872.68106389202 52056.42096984198 45611.60347052062 50321.44774426055 46294.1357335464 38522.217471481745 48911.457233729845 49831.76717388991 47753.51020236611 1.0538090614031939 1.1281407552155762 1.090106690570836 0.9551466117827007 1.05377484358767 0.9694394304704452 0.806688708499863 1.0242484170578599 1.043520506926438 1.0 15.543319164329606 -5.753935796746573 24.404196120629997 0.9755252874597373 1.0944310905096657 0.3644492752140084 0.06744079618097586 139.07066218121125 452297.4240688268 0.019442431644321086 0.03282138053495533 1.762236544671603e-06 5.753935796746573 0.11890580304992837 SFPIKPVPS(ph)PSWSGSCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFPIKPVPSPSWSGSCR 17 1 Q9P0U3;Q9P0U3-2 Q9P0U3 SENP1 Sentrin-specific protease 1 1 SFPIKPVPS(0.642)PS(0.236)WS(0.034)GS(0.088)CR 57.537 0.021333 15238000.0 24307.0 20800.0 25807.0 30034.0 28785.0 24681.0 30572.0 27661.0 29029.0 27194.0 True False 28421.69501486655 22864.88653758889 26422.3367535925 28351.292351541775 23144.785884851455 23386.684911582655 27675.998837887437 26934.928059252103 29453.494207527525 32124.05693241443 0.8847479966388662 0.7117683356648931 0.8225093365132014 0.8825564097084578 0.7204814115958517 0.728011563445605 0.8615349828359092 0.8384659545312194 0.9168672023429206 1.0 14.97136648120539 -8.355214358407592 1.1903999189095196 0.998321634129986 0.7936210306255584 0.5365144024832097 0.060607910616243356 0.3510840739813244 1.0438706974126284 0.057660582445870495 0.01845392316394989 4.413525514645817e-09 8.355214358407592 -0.20470060350442754 SFPIKPVPS(ph)PSWSGSCR ddPTM_PC-9_Lapatinib_30min_R1 1 SFPIKPVPSPSWSGSCR 17 1 Q9P0U3;Q9P0U3-2 Q9P0U3 SENP1 Sentrin-specific protease 1 1 SFPIKPVPS(0.951)PS(0.049)WSGSCR 110.26 0.0019496 3677800.0 5693.1 7914.9 5842.6 6094.7 5705.5 8031.4 5830.5 8015.0 8010.7 5844.2 True False 5611.915350013326 7896.573535340006 5362.24398108821 6542.924569323193 5369.913707444584 7687.915744107823 6132.374761144398 8387.406160196047 7108.450609589309 6854.362183092996 0.8187363317123371 1.1520508144168007 0.7823111527889126 0.954563589514135 0.7834301083024239 1.1216092086687328 0.8946674537086097 1.223659610646847 1.0370695944727066 1.0 12.742806710243569 -6.777043587542384 24.996307962211645 1.0593340439492338 0.9090111714696113 0.2725097520257407 0.1277218896270308 341.22278212535434 546599.7893057314 0.043169837669707736 0.03820215944605454 1.670922905346074e-07 6.777043587542384 -0.1503228724796225 SFPIKPVPSPS(ph)WSGSCR ddPTM_PC-9_AZD4547_30min_R2 1 SFPIKPVPSPSWSGSCR 17 1 Q9P0U3;Q9P0U3-2 Q9P0U3 SENP1 Sentrin-specific protease 1 1 SFPIKPVPS(0.032)PS(0.842)WS(0.032)GS(0.093)CR 107.18 0.00028643 16535000.0 27478.0 29603.0 38950.0 42614.0 37676.0 47357.0 34614.0 38776.0 30974.0 36205.0 True False 36215.43242209439 39171.590831783345 38433.497550522115 32790.00067973693 32445.33773509872 44395.75930366441 37694.57894379685 32784.06018383618 32611.222405325734 34937.47396994433 1.0365784444876995 1.1211912705961942 1.1000651502047718 0.9385338135191225 0.9286686771633942 1.2707203543638204 1.078915406884435 0.9383637813094139 0.933416721351412 1.0 15.092487682630251 -7.76047922034308 24.998046708944088 0.9519176661468646 1.068584570831025 0.23113226301077494 0.09223668001612706 39.141753345661016 1019165.2465987032 0.04926209012118892 0.026329651158354016 1.7358843176168926e-08 7.76047922034308 0.11666690468416052 SFPIKPVPSPS(ph)WSGSCR ddPTM_PC-9_Lapatinib_30min_R1 1 SFPIKPVPSPSWSGSCR 17 1 Q9P0U3;Q9P0U3-2 Q9P0U3 SENP1 Sentrin-specific protease 1 1 SFPIKPVPS(0.221)PS(0.603)WS(0.047)GS(0.129)CR 88.471 0.0012834 11632000.0 32636.0 27623.0 37811.0 31003.0 37770.0 43571.0 33883.0 39729.0 37667.0 34994.0 True False 32170.604655290572 27559.04064065206 34702.32553468082 33283.06404297617 35548.44285867706 41707.56989896182 35637.295949207735 41574.954377845104 33424.545808905656 41042.66627342598 0.783833205205778 0.6714729607734037 0.845518302916632 0.8109381544864704 0.8661338574315216 1.0162003029020155 0.8682987531022546 1.0129691404762309 0.8143853419812335 1.0 15.324836835993972 -5.981658180095811 1.1255698145068078 0.9387639211464285 0.7330427092744333 0.5431263730000595 0.07176915002723024 0.37353483034916735 0.9606204874432446 0.02646960508063938 0.054336675219261464 1.0431381284948272e-06 5.981658180095811 -0.2057212118719952 SFPSS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 2 SFPSSPSK 8 0 A0A0G2JIS2;A2ABF8;A0A0G2JIR1;A2ABF9;A0A0G2JK64;Q96KQ7-2;Q96KQ7;Q96KQ7-3 A0A0G2JIS2 EHMT2 Histone-lysine N-methyltransferase EHMT2 1 SFPS(0.027)S(0.956)PS(0.017)K;SFPS(0.059)S(0.711)PS(0.23)K 117.01 0.0035650999999999994 18069100.0 183171.0 198975.0 188011.0 186919.0 202776.0 224678.0 221680.0 220427.0 222272.0 206715.0 True False 241415.56780651637 263289.7775818021 185517.8512957949 143827.71241976213 174624.05256854143 210628.8491422333 241409.09054893677 186365.07205855314 234020.84414271856 199477.97076914893 1.2102367337890199 1.3198940041680143 0.9300167360860627 0.7210205310651094 0.8754051983546076 1.0559002998180136 1.2102042627469562 0.934263925685453 1.1731663563669659 1.0 17.605869906513895 -5.2617854784351685 24.99962428112491 0.9820259301001617 1.2650653850733413 0.3995787974770242 0.13596721807111461 31.120285232434394 2248108.619589031 0.038621769430698547 0.08940300077916835 5.472862304473518e-06 5.2617854784351685 0.2830394549731796 SFPSS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SFPSSPSK 8 0 A0A0G2JIS2;A2ABF8;A0A0G2JIR1;A2ABF9;A0A0G2JK64;Q96KQ7-2;Q96KQ7;Q96KQ7-3 A0A0G2JIS2 EHMT2 Histone-lysine N-methyltransferase EHMT2 1 SFPS(0.019)S(0.979)PS(0.002)K;SFPS(0.059)S(0.882)PS(0.059)K;SFPS(0.103)S(0.548)PS(0.349)K;S(0.001)FPS(0.37)S(0.588)PS(0.041)K 128.28 0.0036853000000000003 19154300.0 186932.0 232292.0 215947.0 211892.0 250133.0 190819.0 254995.0 223196.0 182082.0 184768.0 True False 218575.8955247062 255352.41459565397 221095.99546355766 200020.37820313254 201121.23424476423 180812.11572234897 230840.02759607212 217337.34149570976 184744.60478469875 218264.9757773171 1.0014245059074725 1.1699193317033834 1.0129705633080082 0.9164107868923577 0.921454454744752 0.8284064590684532 1.0576136953442525 0.9957499627308334 0.8464235002741933 1.0 17.735721119074782 -5.535722620770452 4.990692736722194 0.9385476970410235 1.0880536354357546 0.38322745230045596 0.07546524015416152 0.17080703967226987 11.99013534091911 0.02046528533838322 0.038646523829045785 2.912576755686392e-06 5.535722620770452 0.14950593839473114 SFPSS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 1 SFPSSPSK 8 0 A0A0G2JIS2;A2ABF8;A0A0G2JIR1;A2ABF9;A0A0G2JK64;Q96KQ7-2;Q96KQ7;Q96KQ7-3 A0A0G2JIS2 EHMT2 Histone-lysine N-methyltransferase EHMT2 1 SFPS(0.147)S(0.85)PS(0.003)K 96.665 0.0060501999999999995 8969400.0 57872.0 89750.0 79860.0 74464.0 102310.0 89415.0 85955.0 104260.0 91471.0 77021.0 True False 57046.73466757499 89542.18938922355 73294.21906851458 79940.330964622 96292.32694919905 85590.92888654546 90405.329318955 109104.30021984255 81168.57274766803 90333.97722596861 0.6315091665329174 0.9912348834728663 0.8113693354292435 0.8849420054278456 1.0659591208779144 0.9474943040805287 1.0007898699379516 1.2077880723320789 0.8985386810172931 1.0 16.462981108734667 -3.720527518020314 0.4557056376150446 1.038113500889576 1.4039068913227652e-12 0.4774438536906743 0.10571334764584567 11.066706339703813 0.8461386921286415 0.06730078067481692 7.600347159605579 0.00019031476454045397 3.720527518020314 -1.0381135008881721 SFPSSPS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 SFPSSPSK 8 0 A0A0G2JIS2;A2ABF8;A0A0G2JIR1;A2ABF9;A0A0G2JK64;Q96KQ7-2;Q96KQ7;Q96KQ7-3 A0A0G2JIS2 EHMT2 Histone-lysine N-methyltransferase EHMT2 1 SFPS(0.001)S(0.49)PS(0.509)K 110.54 0.0037603000000000003 7794500.0 31888.0 44731.0 40010.0 45973.0 58908.0 50589.0 56961.0 51305.0 44851.0 48913.0 True False 31433.27127245698 44627.42811776443 36720.532243066285 49354.007781432236 55443.14725758403 48425.426398718875 59910.16186768647 53688.81759811082 39799.4080780319 57367.5468775243 0.5479277567779709 0.7779211513617772 0.640092425800637 0.8603123275743269 0.9664549083116849 0.8441257999423224 1.044321487122161 0.9358743840438688 0.6937617214659858 1.0 15.807947207051305 -5.849974879510261 4.346795510362723 0.9137797493486574 0.667143571607715 0.5513559991199621 0.10434248745300584 0.16428403255701635 5.643444902270546 0.029262918188718477 0.04538433624249511 1.4126192510745237e-06 5.849974879510261 -0.24663617774094238 SFPVFS(ph)PPGPPR ddPTM_PC-9_AZD4547_30min_R2 1 SFPVFSPPGPPR 12 0 H3BSV5;A0A0A0MTL6;Q6ZS17-2;Q6ZS17;Q6ZS17-3;Q6ZS17-4;H3BS40;H3BUP6;H3BQI5;H3BU12 H3BSV5 FAM65A Protein FAM65A 1 S(0.019)FPVFS(0.981)PPGPPR 71.888 0.026333999999999996 3911100.0 14284.0 15863.0 23061.0 28506.0 25708.0 22303.0 21060.0 30961.0 21922.0 23936.0 True False 18826.014874342996 20990.4045321278 22755.196072210278 21934.382113309734 22138.887952381312 20908.38988427536 22934.299201374048 26176.688863001673 23080.752165349983 23098.00792555139 0.8150492862857388 0.9087538890705754 0.9851583801319123 0.9496222437886328 0.9584760739427627 0.9052031652108908 0.9929124310327972 1.1332877253905778 0.9992529329690671 1.0 14.495480812149403 -2.351715690969687 0.3016350996401669 1.0338986930440515 1.0187437971939371e-15 0.5342943308978991 0.05347693229343139 28.723381366642684 0.6452176448779073 0.06020517183942126 14.598763028772076 0.004449224387286191 2.351715690969687 -1.0338986930440504 SFPVFS(ph)PPGPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SFPVFSPPGPPR 12 0 H3BSV5;A0A0A0MTL6;Q6ZS17-2;Q6ZS17;Q6ZS17-3;Q6ZS17-4;H3BS40;H3BUP6;H3BQI5;H3BU12 H3BSV5 FAM65A Protein FAM65A 1 S(0.001)FPVFS(0.999)PPGPPR;S(0.004)FPVFS(0.996)PPGPPR;S(0.013)FPVFS(0.987)PPGPPR;S(0.002)FPVFS(0.998)PPGPPR 90.79299999999999 0.01426 7386600.0 38323.8 39931.600000000006 45876.9 49382.1 54051.600000000006 45376.799999999996 58160.100000000006 51489.799999999996 47298.4 38668.8 True False 44811.26241044729 43895.74534924928 46970.779285112105 46615.3810359283 43460.576992657196 42997.16072670898 52650.75428534006 50138.24730795264 47990.04962021841 45679.147337947616 0.9810004131408264 0.9609580718417485 1.0282761833886396 1.0204958663316142 0.951431441377905 0.9412864125637784 1.1526212145733472 1.097617845994701 1.0505898734311756 1.0 15.479248100679376 -7.2514649605778905 24.999472759161637 1.0833420560178648 0.982341214729882 0.5186022822808694 0.044370887460654214 540.0103716194058 1353462.1100721671 0.017348121587887982 0.01327970289526176 5.6044763315629904e-08 7.2514649605778905 -0.10100084128798281 SFPVFS(ph)PPGPPR ddPTM_PC-9_Lapatinib_30min_R1 1 SFPVFSPPGPPR 12 0 H3BSV5;A0A0A0MTL6;Q6ZS17-2;Q6ZS17;Q6ZS17-3;Q6ZS17-4;H3BS40;H3BUP6;H3BQI5;H3BU12 H3BSV5 FAM65A Protein FAM65A 1 S(0.003)FPVFS(0.997)PPGPPR 83.137 0.011351 2973900.0 18903.0 13472.0 16898.0 14870.0 16747.0 14473.0 12621.0 14776.0 16419.0 11597.0 True False 18633.439753614348 13440.806411717205 15508.711668166323 15963.589404865843 15761.974385868807 13854.023528210839 13274.45362497272 15462.546902440026 14569.719320265009 13601.52599796883 1.3699521477514327 0.9881837092194194 1.1402185071353244 1.1736616470276753 1.1588386765001666 1.0185639118933945 0.9759532589913108 1.13682441990326 1.0711826983561081 1.0 13.731480900598449 -6.753974797715901 24.50270152924412 1.0450219067711508 1.1552571329975725 0.29837817704260017 0.09549594936791184 195.94674903516167 643199.5241551496 0.03111557843385751 0.030505074111412435 1.7620782975596793e-07 6.753974797715901 0.11023522622642168 SFQS(ph)LACSPGLPAADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFQSLACSPGLPAADR 16 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;A0A087WXJ0 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 S(0.01)FQS(0.57)LACS(0.42)PGLPAADR 168.68 3.7902e-05 8509100.0 39000.0 40490.0 43419.0 48030.0 52664.0 53789.0 50445.0 56912.0 47808.0 36281.0 True False 45601.929714888516 44509.57961091225 44454.273627474475 45339.034815360996 42344.86725168723 50968.21014987724 45666.48440982701 55418.12030324843 48507.10155614993 42858.458099762 1.0640123732109195 1.0385249863004153 1.0372345529556355 1.0578783471357027 0.988016581303992 1.1892217408110692 1.0655186032014672 1.2930497913445975 1.1317976359121351 1.0 15.3872923272811 -6.764867907155082 24.99948214560371 1.1498332362745378 1.0383687986251073 0.2966742766113115 0.0745127966150356 99.01205430228887 721950.6418646515 0.024511268134321248 0.022488331705176938 1.7184309770800251e-07 6.764867907155082 -0.11146443764943048 SFQSLACS(ph)PGLPAADR ddPTM_PC-9_AZD4547_30min_R2 4 SFQSLACSPGLPAADR 16 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;A0A087WXJ0 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 SFQS(0.01)LACS(0.99)PGLPAADR;SFQS(0.01)LACS(0.99)PGLPAADR;SFQSLACS(1)PGLPAADR;SFQS(0.001)LACS(0.999)PGLPAADR 194.67 9.1648e-12 48898300.0 113080.0 94096.0 149234.0 208827.0 165329.0 140210.0 110108.0 170816.0 128664.0 148192.0 True False 149037.08778988424 124510.69185243004 147255.0596522367 160685.16149498828 142375.92213627105 131442.64653518592 119907.39869254029 144420.31216118665 135464.91636723815 143003.84318613444 1.0421893878467092 0.870680738911096 1.0297279875238656 1.1236422596408109 0.9956090617155926 0.9191546437259003 0.8384907427730336 1.0099051112438182 0.9472816488639149 1.0 17.12569439396546 -6.65760089715558 5.76327669638065 0.9373716128886783 1.0130530041646473 0.18574456826495467 0.0728654681913291 0.37949050422232605 18.148023151067704 0.02568703062350754 0.025571203018747737 2.1998805645817422e-07 6.65760089715558 0.07568139127596896 SFQSLACS(ph)PGLPAADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFQSLACSPGLPAADR 16 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;A0A087WXJ0 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 SFQSLACS(1)PGLPAADR 145.48 2.9616999999999998e-05 7956600.0 20853.0 19983.0 20752.0 26337.0 32944.0 26082.0 25248.0 27871.0 27431.0 18392.0 True False 24383.001034476143 21966.78017695381 21246.80638239826 24861.423275706067 26488.859690482765 24714.21400526313 22856.326660309485 27139.4157817655 27832.126480646508 21726.324009008105 1.1222791772950884 1.0110675035429835 0.9779291873576482 1.1442995725092793 1.2192057745019373 1.1375239545822935 1.0520107612697325 1.2491489941194394 1.281032468682085 1.0 14.407156477556978 -5.870457515323038 6.541157896355054 1.1642615697639231 1.0351652019107525 0.27510494754598236 0.08700427254164728 0.26179480540967426 14.134031579954723 0.02482163149365174 0.03716725557281235 1.3475425416852269e-06 5.870457515323038 -0.1290963678531707 SFQSLACS(ph)PGLPAADR ddPTM_PC-9_Lapatinib_30min_R1 4 SFQSLACSPGLPAADR 16 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;A0A087WXJ0 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 SFQS(0.015)LACS(0.985)PGLPAADR;SFQS(0.002)LACS(0.998)PGLPAADR;SFQS(0.002)LACS(0.998)PGLPAADR;SFQSLACS(1)PGLPAADR 187.04 5.2571e-08 37946200.0 111937.0 103110.0 141944.0 128858.0 136085.0 139222.0 128380.0 139363.0 162290.0 107281.0 True False 110340.75785326822 102871.25513005964 130273.91223968525 138334.6471776869 128080.74785340393 133267.79960233325 135026.8882318355 145838.3137496443 144011.1912105371 125824.37790705277 0.8769426059453885 0.8175780944933522 1.035363054494252 1.0994264345171294 1.0179326930431394 1.0591572302529402 1.073137737518406 1.1590624660777258 1.144541253499533 1.0 16.9410519394075 -5.3538073387585 4.1320949177282875 1.081060276411218 0.8469004721714709 0.7765409562907482 0.04887590690648796 0.09791914319609629 2.960607500767569 0.013708937478438085 0.031064151257916756 4.427847564873452e-06 5.3538073387585 -0.23415980423974714 SFREPAPAEALPQQYPEPAPAALCGPPPRAPS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 SFREPAPAEALPQQYPEPAPAALCGPPPRAPSR 33 2 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 SFREPAPAEALPQQY(0.06)PEPAPAALCGPPPRAPS(0.94)R;SFREPAPAEALPQQYPEPAPAALCGPPPRAPS(1)R 70.605 4.6541e-06 11683600.0 21567.1 10884.5 30867.0 59520.0 51658.0 35794.0 21046.0 33473.0 17892.6 33879.0 True False 28424.989176452138 14402.701767001521 30457.683411860464 45798.58357483322 44486.17838198668 33555.79552157792 22919.053228495657 28300.516983019126 18838.366307533128 32692.906521965044 0.8694543312432174 0.44054516099157254 0.9316297219213953 1.4008721905488275 1.3607287670216233 1.0263937682944506 0.701040551811974 0.8656470162420448 0.5762218264343181 1.0 14.996690023354628 -11.00355676787327 3.4278901090624223 1.0013432516652983 0.9189546230238183 0.007741033646530782 0.2895224809787938 74074550.47861405 79268518.40351489 658621.6438452668 0.07828090395491076 9.918436840420876e-12 11.00355676787327 -0.08238862864148 SFS(ph)ADNFIGIQR ddPTM_PC-9_AZD4547_30min_R2 1 SFSADNFIGIQR 12 0 Q8N7R7-3;Q8N7R7-2;Q8N7R7 Q8N7R7-3 CCNYL1 Cyclin-Y-like protein 1 1 S(0.002)FS(0.998)ADNFIGIQR 149.35 0.00016057 14136000.0 12299.0 32124.0 29014.0 31278.0 28530.0 19000.0 24497.0 28989.0 22899.0 19392.0 True False 16209.826164907885 42507.454780941436 28629.255402589184 24067.3403402828 24569.101963647063 17811.926996423423 26677.185543022813 24509.41615094974 24109.394390764974 18713.09198246543 0.8662291715392005 2.271535608373637 1.5299051289554613 1.2861231250738476 1.3129365252235623 0.9518430739887124 1.4255893984820847 1.3097470035371808 1.2883704314260838 1.0 14.191760335734717 -5.726453839555182 4.086198477223319 1.235557920522111 1.6403137204341927 0.15510825768538639 0.3447355029463588 0.3230685162549609 11.61172443378808 0.09165420294728954 0.15831981874206397 1.8773539486285171e-06 5.726453839555182 0.40475579991208166 SFS(ph)ADNFIGIQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFSADNFIGIQR 12 0 Q8N7R7-3;Q8N7R7-2;Q8N7R7 Q8N7R7-3 CCNYL1 Cyclin-Y-like protein 1 1 S(0.123)FS(0.877)ADNFIGIQR;S(0.017)FS(0.983)ADNFIGIQR 141.65 5.6421e-05 18517800.0 23000.6 29295.4 27963.5 22862.1 58383.0 25646.8 23396.6 25870.0 21684.0 13079.6 True False 26894.147297442694 32203.653705446257 28630.255892164292 21581.210656928244 46943.270255872245 24301.836659388948 21180.304671284746 25190.939911530753 22001.08747790233 15450.827941943362 1.7406282303121694 2.0842671879106933 1.8529916972567917 1.3967672630890626 3.0382365548475487 1.5728501249708648 1.3708200460758446 1.6303941773337944 1.4239423000871947 1.0 13.915396527435224 -7.971860768795343 0.7918344304234818 1.077696928558734 1.9662412954492796 0.32375563879255576 0.4312309177218813 0.7648446008016268 0.9444441259729759 0.40934051002454935 0.17211736883878298 1.0669381179077719e-08 7.971860768795343 0.8885443668905457 SFS(ph)ADNFIGIQR ddPTM_PC-9_Lapatinib_30min_R1 1 SFSADNFIGIQR 12 0 Q8N7R7-3;Q8N7R7-2;Q8N7R7 Q8N7R7-3 CCNYL1 Cyclin-Y-like protein 1 1 S(0.035)FS(0.965)ADNFIGIQR 144.88 0.0001028 9218800.0 58833.0 41699.0 21509.0 17017.0 19181.0 11038.0 12037.0 8129.8 27872.0 7611.3 True False 57994.030631349175 41602.44852747892 19740.61304714104 18268.486947047895 18052.81129129692 10565.93047083474 12660.216962506673 8507.540187294047 24732.761854828335 8926.903063580248 6.496545354900485 4.66034505260929 2.2113618694570896 2.04645293187726 2.022292743935836 1.1836053775403201 1.4182093019646986 0.9530225798018233 2.770587030986415 1.0 13.12394404458452 -4.934883570441015 1.221432439975835 1.5425520870718707 8.086804220406322 0.906863036489507 0.5176488228181484 0.3013707340145901 0.4677900712193648 0.15444547622726604 2.33940194169675 1.1617600271407065e-05 4.934883570441015 6.544252133334451 SFS(ph)ASQSTDREGASPVTEVR ddPTM_PC-9_AZD4547_30min_R2 1 SFSASQSTDREGASPVTEVR 20 1 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 S(0.17)FS(0.562)AS(0.08)QS(0.17)T(0.017)DREGASPVTEVR 67.655 0.026262 5775000.0 9258.9 6512.4 11849.0 23316.0 18762.0 11084.0 9897.5 12388.0 10239.0 11637.0 True False 12203.037602916153 8617.405943076914 11691.87451800093 17940.85642860905 16157.220155693887 10390.915727808273 10778.358326001888 10473.719247920431 10780.212636667216 11229.592172027134 1.0866857331928639 0.7673836957804073 1.0411664412110475 1.5976409609335276 1.4388073857162376 0.9253155028810396 0.9598174324487697 0.9326891918666842 0.9599825596089482 1.0 13.455017913514332 -6.863914313974114 20.46432921878896 0.9515844699722872 1.178439599703251 0.23042635662274435 0.2105468957278513 6.161090318780186 1211.2585766353943 0.0855452818873598 0.07544397350287238 1.3679987042484082e-07 6.863914313974114 0.2268551297309639 SFS(ph)ASQSTDREGASPVTEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFSASQSTDREGASPVTEVR 20 1 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 S(0.096)FS(0.786)AS(0.053)QS(0.046)T(0.018)DREGAS(0.001)PVTEVR 54.355 0.011576999999999999 6978700.0 5290.3 4352.4 7282.9 8076.3 10030.0 10355.0 8389.8 8539.1 10722.0 8263.9 True False 6185.8433018121705 4784.477507990478 7456.551956552055 7623.811094717879 8064.693500957449 9811.96557106432 7595.057407108066 8314.957672924318 10878.788965968864 9762.079653003597 0.6336604004156953 0.49010842751302386 0.7638282232472692 0.7809617792221338 0.8261245336669737 1.005110173224757 0.7780163322854284 0.8517608919904656 1.1143925631278453 1.0 13.252972808010613 -5.075373682113264 0.3697936921077408 0.999640828369173 0.26705781632718695 0.6870419084597699 0.09756799114422943 2.940344647635967 0.37751336346068476 0.09194485891448835 0.9437768571812547 8.40671487304686e-06 5.075373682113264 -0.7325830120419861 SFS(ph)ASQSTDREGASPVTEVR ddPTM_PC-9_Lapatinib_30min_R1 1 SFSASQSTDREGASPVTEVR 20 1 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 S(0.164)FS(0.576)AS(0.207)QS(0.014)T(0.008)DREGAS(0.012)PVT(0.019)EVR 87.49600000000001 0.0035323999999999998 2137100.0 8761.5 4836.4 6275.6 4672.7 7661.9 6981.8 6512.5 5830.5 8311.4 5733.2 True False 8636.55940333768 4825.201612947531 5759.644392516543 5016.345945670249 7211.242105874974 6683.204689370716 6849.685384092768 6101.4063152867175 7375.282609077937 6724.1759809911955 1.2844041303726534 0.7175900253931574 0.8565576523872487 0.7460164576077619 1.0724350650935792 0.9939068680331533 1.0186653953519924 0.9073834968827397 1.0968306941887567 1.0 12.715141767056062 -6.286013833733421 24.97083664914385 1.0093810139907033 0.8848465675316916 0.11463993419547647 0.15170217085998156 1560.868405580053 1586040.3992460042 0.04567444802479013 0.05181358695763028 5.175903447024272e-07 6.286013833733421 -0.1245344464590118 SFS(ph)DHIR ddPTM_PC-9_AZD4547_30min_R2 2 SFSDHIR 7 0 Q96QB1-6 Q96QB1-6 1 SFS(1)DHIR;SFS(1)DHIR 112.41 0.005199199999999999 4962600.0 20313.5 17333.9 27677.0 38769.0 34213.0 26332.0 27517.0 36516.0 29260.0 29530.0 True False 26772.770452951976 22936.744192110582 27309.984896169444 29831.406025079094 29463.115509367573 24685.455877359032 29965.959692507575 30873.29125420266 30806.623864526075 28496.16368823246 0.9395219211211872 0.804906388209103 0.9583740883495538 1.0468569155994154 1.0339327016686957 0.8662729533503113 1.051578732504336 1.0834192136168785 1.0810796920445724 1.0 14.798480088283082 -5.501634636139705 5.126250531522402 1.0210444422504943 0.8725801115631313 0.45878367974656253 0.06542027321997432 0.16448681520067335 12.274366993589522 0.01842522876385641 0.036819248409209006 3.15039757037007e-06 5.501634636139705 -0.14846433068736298 SFS(ph)DHIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFSDHIR 7 0 Q96QB1-6 Q96QB1-6 1 SFS(1)DHIR 88.37 0.0098137 2033900.0 4976.9 4282.3 7276.4 7197.3 6630.8 5828.3 6303.7 8435.3 6432.0 4672.2 True False 5819.390871744324 4707.418443265241 7449.896971900666 6794.058614961427 5331.542339596074 5522.6536878642355 5706.567901164166 8213.882312939131 6526.055831851493 5519.232874885147 1.0543840065573284 0.8529117270419941 1.3498066018922414 1.230978791613827 0.9659933654651276 1.0006197986308305 1.0339422217771375 1.488228980211323 1.1824208145932413 1.0 12.430252043602469 SFS(ph)DHIR ddPTM_PC-9_Lapatinib_30min_R1 1 SFSDHIR 7 0 Q96QB1-6 Q96QB1-6 1 SFS(1)DHIR 78.113 0.020161000000000002 0.0 17433.0 15513.0 18085.0 16959.0 18341.0 18308.0 15490.0 15088.0 20613.0 12652.0 True False 17184.402223179346 15477.080601615882 16598.121110118816 18206.221433565555 17262.218439793378 17525.00951803247 16291.996406847902 15789.04356145201 18291.346875487092 14838.881342269702 1.1580658829199102 1.0430085829669802 1.118556091073913 1.2269268156827782 1.1633099585897093 1.1810195872455105 1.0979261866889447 1.0640319305253623 1.2326634638813894 1.0 13.857094715255387 -9.637727241026862 7.37380520030337 1.0000000013846042 1.1397442543798106 0.3359916214921994 0.06009766334327664 4329568.884727168 628760.210694483 0.05968047686724119 0.01492011921388095 2.3028876936520184e-10 9.637727241026862 0.13974425299520643 SFS(ph)EDTLMDGPAR ddPTM_PC-9_AZD4547_30min_R2 2 SFSEDTLMDGPAR 13 0 Q9BRG2;M0QZQ6 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 S(0.001)FS(0.691)EDT(0.308)LMDGPAR;S(0.003)FS(0.738)EDT(0.26)LMDGPAR 78.28699999999999 0.013355 30066300.0 26934.0 26549.0 37402.0 52240.0 47680.0 37905.0 35520.0 41930.0 33390.0 35971.0 True False 35498.45173799732 35130.44505600839 36906.02504196734 40196.875099954406 41060.45501670846 35534.79435786474 38681.21118864229 35450.681955546024 35154.92723296398 34711.6662387203 1.0226663132177554 1.012064497693889 1.0632167522053224 1.1580220558561214 1.182900720879431 1.0237132989665085 1.1143576606960466 1.0212901251050104 1.012769798810442 1.0 15.083132999012813 -7.869658171514018 6.231777627171258 1.010143087300886 1.0833549855527196 0.2671426130408665 0.05414497749760253 0.3269271478446069 16.6552590180562 0.0332788830621178 0.015780723100815935 1.3500250546328358e-08 7.869658171514018 0.0732118982518335 SFS(ph)EDTLMDGPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFSEDTLMDGPAR 13 0 Q9BRG2;M0QZQ6 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 S(0.035)FS(0.576)EDT(0.389)LMDGPAR;S(0.028)FS(0.597)EDT(0.376)LMDGPAR 90.229 0.0050317 83998000.0 40462.0 43602.0 43939.0 50629.0 53464.0 53279.0 54438.0 48133.0 47234.0 40773.0 True False 47311.4174390723 47930.518404420756 44986.67239958543 47792.42127143266 42988.11299453528 50484.95544768094 49281.23854301048 46869.55975112908 47924.70789205126 48164.82214110957 0.9822815768002415 0.9951353762710392 0.9340151255575482 0.9922681979685114 0.8925209537490252 1.0481707022559748 1.023179082829998 0.9731077094775575 0.9950147381764466 1.0 15.555692217884626 -6.786551577940597 24.999753901309912 1.0071689419111078 0.961671165545196 0.34196837028439553 0.03365145303735566 292.76131403722036 291448.22278030653 0.011892319700635446 0.01049223937279146 1.634738993752186e-07 6.786551577940597 -0.04549777636591179 SFS(ph)EDTLMDGPAR ddPTM_PC-9_Lapatinib_30min_R1 1 SFSEDTLMDGPAR 13 0 Q9BRG2;M0QZQ6 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 S(0.009)FS(0.991)EDTLMDGPAR 159.58 0.00027006 10371000.0 16097.0 14656.0 19058.0 14219.0 12665.0 15778.0 15224.0 14134.0 22207.0 14814.0 True False 15867.45382817174 14622.064932461954 17491.124806007432 15264.712693193513 11920.069600348028 15103.211720314415 16012.224228395902 14790.717238703795 19705.81380992296 17374.580161585778 0.913256820055646 0.8415780293091927 1.0067077675165543 0.8785658445401137 0.6860637488497496 0.8692705999139345 0.921589130757705 0.8512848714126193 1.134174962885803 1.0 14.084690496601931 -8.252773462522313 24.99390836583894 1.0670874845773888 0.870290846737584 0.4775099757791895 0.08202647546299022 493.7385554193299 1424032.5062596682 0.059509351644782375 0.021694529303573504 5.587615809658375e-09 8.252773462522313 -0.19679663783980483 SFS(ph)EGGER ddPTM_PC-9_AZD4547_30min_R2 1 SFSEGGER 8 0 G3V2D5;G3V515;G3V2P5;Q07352 G3V2D5 ZFP36L1 Zinc finger protein 36, C3H1 type-like 1 1 S(0.123)FS(0.877)EGGER 80.755 0.01885 47546000.0 56466.0 52203.0 60517.0 82372.0 60532.0 66767.0 55090.0 60190.0 54889.0 63106.0 True False 74421.01343423763 69076.59886469567 59714.505038894655 63382.408034713735 52128.1766583766 62592.04893527389 59992.90327652879 50889.01852860274 57790.32048188559 60896.678147971485 1.222086584976009 1.1343245800181083 0.9805872316022839 1.0408188092083157 0.8560101838676898 1.0278401193441595 0.9851588806002418 0.835661649802123 0.9489897025493275 1.0 15.894075912276188 -4.80914043445288 0.9071915447233526 0.940885990118988 1.384765421572234 0.6758056061243882 0.06254045997260747 1.2087380842796076 0.7996264459273933 0.021882730687595386 0.5301253783622054 1.5518851077111014e-05 4.80914043445288 0.44387943145324604 SFS(ph)EGGER ddPTM_PC-9_Lapatinib_30min_R1 1 SFSEGGER 8 0 G3V2D5;G3V515;G3V2P5;Q07352 G3V2D5 ZFP36L1 Zinc finger protein 36, C3H1 type-like 1 1 S(0.226)FS(0.774)EGGER 92.23899999999999 0.0081241 34879000.0 41808.0 47144.0 36195.0 46686.0 60869.0 78769.0 78166.0 69093.0 96502.0 76770.0 True False 41211.81025335179 47034.84096451873 33219.18681674045 50119.444179930506 57288.805093058356 75400.23348950734 82213.05301082469 72303.31301639751 85632.92854888937 90039.59221040513 0.45770765106363154 0.5223795422641119 0.36893977417305074 0.5566378406380501 0.6362623784344279 0.8374119833118698 0.9130766920701803 0.8030168866984497 0.9510586004074936 1.0 16.45827190238596 -6.583297566553668 1.4328096398539851 0.9087863306480212 0.4569646407136912 0.9158837348891908 0.06167316296511669 0.10709564211984769 0.45474890932809836 0.025599800671061317 0.026979907369085367 2.610372186782274e-07 6.583297566553668 -0.45182168993433 SFS(ph)EHDLAQLR ddPTM_PC-9_AZD4547_30min_R2 1 SFSEHDLAQLR 11 0 Q8WWL2-4;Q8WWL2-3;Q8WWL2-2;Q8WWL2 Q8WWL2-4 SPIRE2 Protein spire homolog 2 1 S(0.086)FS(0.914)EHDLAQLR 60.345 0.036255 3462200.0 13435.0 10979.0 16155.0 24576.0 19472.0 17203.0 13991.0 21628.0 17366.0 20065.0 True False 17707.050534640024 14527.747043953299 15940.774144510506 18910.382895414994 16768.64891118598 16127.293690498545 15236.171895841615 18285.889561997345 18283.93130660834 19362.530457310684 0.9145008486199384 0.7503020886646599 0.8232794871339644 0.976648322754479 0.8660360249997523 0.8329125021161367 0.7868894992539012 0.9443956512973833 0.9442945149612355 1.0 14.240979887929123 -7.894833199064849 6.837510460263175 0.962938084131032 0.850226649622999 0.42117392017731725 0.06094918173613985 0.2285242536480637 12.987156923132948 0.03533621706211519 0.016807333420252545 1.27399229354785e-08 7.894833199064849 -0.112711434508033 SFS(ph)EHDLAQLR ddPTM_PC-9_Lapatinib_30min_R1 1 SFSEHDLAQLR 11 0 Q8WWL2-4;Q8WWL2-3;Q8WWL2-2;Q8WWL2 Q8WWL2-4 SPIRE2 Protein spire homolog 2 1 S(0.035)FS(0.965)EHDLAQLR 75.589 0.012217 1797800.0 21806.0 19408.0 19987.0 16375.0 23324.0 22505.0 16795.0 20283.0 24283.0 20577.0 True False 21495.042441269365 19363.061968423957 18343.746012051135 17579.272125398667 21952.128176748327 21542.513611717335 17664.56292143387 21225.422226731927 21547.992828673825 24133.707032870985 0.8906647624416894 0.8023243980732327 0.7600882030707626 0.7284115988254544 0.9096044858275909 0.8926317694325058 0.731945693107739 0.8794928270995472 0.8928588052935538 1.0 14.558761915789907 -8.52357169979727 1.4434012800691547 0.9982445363073398 0.8171020080234522 0.43006824879117456 0.06374370415893789 0.43397611115458407 1.9960994115949604 0.063202010098008 0.01882170366147592 2.9952170565928506e-09 8.52357169979727 -0.18114252828388755 SFS(ph)EPFGR ddPTM_PC-9_AZD4547_30min_R2 1 SFSEPFGR 8 0 A0A494C127;A0A494C1S3;A0A494C175;A0A0S2Z4A4;A0A494C1P6;P58340-2;P58340-5;P58340-4;P58340;P58340-3 A0A494C127 MLF1 Myeloid leukemia factor 1 1 S(0.33)FS(0.67)EPFGR 96.665 0.0060501999999999995 7062500.0 23939.0 21744.0 27658.0 40137.0 34969.0 27624.0 32441.0 45410.0 32125.0 35986.0 True False 31551.104037867306 28772.32277290467 27291.236848583834 30884.034760468414 30114.15795887747 25896.666913115823 35328.18615345562 38392.92791799056 33823.06191551268 34726.141093285914 0.9085692519969493 0.8285493828874531 0.7858989219467414 0.8893598248507851 0.8671898751427886 0.7457398402992375 1.017336941025276 1.105591543121778 0.9739942547792089 1.0 15.083734481173735 -7.346155563477157 7.18072960315148 1.034875304089346 0.8387268680469714 0.7359317665923162 0.05467419362275134 0.13373028201363107 9.85316203364362 0.02257907048526669 0.015156171096623886 4.506552517525984e-08 7.346155563477157 -0.19614843604237453 SFS(ph)EPFGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFSEPFGR 8 0 A0A494C127;A0A494C1S3;A0A494C175;A0A0S2Z4A4;A0A494C1P6;P58340-2;P58340-5;P58340-4;P58340;P58340-3 A0A494C127 MLF1 Myeloid leukemia factor 1 1 S(0.405)FS(0.595)EPFGR;S(0.256)FS(0.744)EPFGR 68.626 0.043082999999999996 11192500.0 40877.0 36131.0 36410.0 38716.0 44826.0 48340.0 46164.0 54217.0 43165.0 41092.0 True False 47796.66874244866 39717.84689853965 37278.15248569394 36546.868038965535 36042.66708613347 45804.96530229352 41791.011721582996 52793.86119765995 43796.20646484292 48541.654315906955 0.9846526538092426 0.8182219468676869 0.7679621350168531 0.752897043869171 0.74251006880749 0.9436218428856342 0.8609309326297148 1.0875991340154956 0.9022396760485156 1.0 15.566935656408608 -7.230084883186159 1.7169689479044883 0.9873447795250125 0.8119595134230754 0.4013781522435924 0.0863005557023208 0.36287359332192515 2.0917575174481255 0.04640257426241785 0.029264006480232998 5.887285766626369e-08 7.230084883186159 -0.17538526610193717 SFS(ph)EPFGR ddPTM_PC-9_Lapatinib_30min_R1 1 SFSEPFGR 8 0 A0A494C127;A0A494C1S3;A0A494C175;A0A0S2Z4A4;A0A494C1P6;P58340-2;P58340-5;P58340-4;P58340;P58340-3 A0A494C127 MLF1 Myeloid leukemia factor 1 1 S(0.453)FS(0.547)EPFGR 94.40899999999999 0.0067423000000000005 5744000.0 20861.0 13487.0 16275.0 16009.0 30489.0 26287.0 28597.0 21225.0 20500.0 26938.0 True False 20563.518314561123 13455.771680138805 14936.93232331677 17186.355264458467 28695.69696368031 25162.766287989933 30077.612733804373 22211.190985672 18191.074125429855 31594.197407371248 0.6508637661978856 0.42589376481516306 0.47277454561424725 0.543971889611879 0.9082584562501124 0.7964363190982405 0.9519979996955694 0.7030148827420413 0.5757726297293342 1.0 14.9473719968029 -6.185180140334438 6.107213072903761 0.8124948332955724 0.5093574070584296 0.5704769023825507 0.12692343129164071 0.1784038417876255 11.38206642279349 0.03822242422776438 0.04951266278226549 6.528596978163362e-07 6.185180140334438 -0.3031374262371428 SFS(ph)GNPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFSGNPR 7 0 Q9NQS3-3 Q9NQS3-3 1 S(0.104)FS(0.896)GNPR 72.87899999999999 0.037712999999999997 19901000.0 37280.0 36123.0 52953.0 48109.0 50899.0 40832.0 51317.0 44824.0 41864.0 36599.0 True False 43590.76768643704 39709.05271140978 54215.60034537081 45413.60870148245 40925.70633152874 38690.698039372124 46455.8822570937 43647.417494953756 42476.18180109315 43234.108982475394 1.008249475063918 0.9184658512912925 1.254000640266385 1.0504115794288833 0.9466069104862934 0.8949114241039429 1.0745192476598564 1.009559778661008 0.982469230910033 1.0 15.399882336461767 -6.143457099775924 7.045611711386312 0.9853944220059387 1.062944158418216 0.1399142392326267 0.08880013038160531 0.5466615987348872 29.68553861684267 0.027456701966654416 0.0355926474870098 7.186921483025535e-07 6.143457099775924 0.07754973641227725 SFS(ph)LASSSNSPISQR ddPTM_PC-9_AZD4547_30min_R2 3 SFSLASSSNSPISQR 15 0 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 SFS(0.999)LASSSNSPISQR;S(0.013)FS(0.949)LAS(0.032)S(0.003)S(0.003)NSPISQR;S(0.141)FS(0.526)LAS(0.218)S(0.09)S(0.016)NS(0.01)PISQR 170.35 0.00015333 45266500.0 37586.1 38133.8 49568.0 63433.0 56399.0 49995.0 43042.0 67967.0 40101.6 48051.0 True False 49537.69796055327 50459.805102897 48910.69593284416 48809.50188008055 48568.972367603645 46868.804746641516 46872.65461659747 57464.26187628415 42221.28870696102 46368.74911558611 1.0683423405938282 1.0882287330441645 1.0548202585953221 1.0526378824326321 1.0474505630189184 1.0107843243691756 1.0108673516241562 1.239288593553378 0.9105548351479901 1.0 15.50086518736859 -5.428695343057136 3.930816289141642 1.0471019171211424 1.0781148863121484 0.03155052201122588 0.07789307129957755 1.1160639742640703 30.788718876333316 0.02010461332954983 0.04427101761851736 3.7265303013944026e-06 5.428695343057136 0.031012969191005935 SFS(ph)LASSSNSPISQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFSLASSSNSPISQR 15 0 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 S(0.054)FS(0.944)LAS(0.002)S(0.001)SNSPISQR 102.72 0.0014254 7944300.0 14585.0 12152.0 5945.1 7296.5 12146.0 9496.5 5248.8 10298.0 7054.9 4828.5 True False 17053.95243311921 13358.37025022983 6086.853730917305 6887.7007605721665 9766.078490790547 8998.486822367197 4751.595665978788 10027.688411632924 7158.064565940474 5703.868827615031 2.9898921150769193 2.341984125854344 1.067144759965038 1.207548940681396 1.7121849723311495 1.5776111082361182 0.8330478504298953 1.7580503189491858 1.2549490148309543 1.0 12.477725089037632 -5.065103824170687 3.4017007637506933 1.3349928938569184 2.9192728413249904 0.782885548343175 0.2953951704126638 0.1044877543105631 2.294636237749523 0.07673737648551983 0.29056613445232304 8.607879441864253e-06 5.065103824170687 1.584279947468072 up SFS(ph)LASSSNSPISQR ddPTM_PC-9_Lapatinib_30min_R1 2 SFSLASSSNSPISQR 15 0 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 S(0.003)FS(0.972)LAS(0.015)S(0.005)S(0.005)NSPISQR;SFS(0.876)LAS(0.122)S(0.001)SNSPISQR 137.39 4.1232e-05 22439700.0 31724.6 32234.0 33087.0 26766.0 24294.0 22550.0 20267.0 21348.7 22938.0 22894.3 True False 31272.201386420886 32159.36415345106 30366.714579513475 28734.460928758526 22865.074683841685 21585.589066617445 21316.32609280738 22340.638539261054 20354.48089215171 26851.54925026281 1.1646330383009393 1.197672575750403 1.1309110806415112 1.0701230182641057 0.8515365154812395 0.8038861693019882 0.7938583317533808 0.8320055699967626 0.7580374861220527 1.0 14.712717709145277 -6.142974828295632 2.1293715482110187 0.8216792005659188 1.1706863292604759 0.850498259456674 0.06261061202800873 0.103942540903757 0.9267936732611174 0.01937602572579363 0.02725422904809261 7.194906784686323e-07 6.142974828295632 0.3490071286945571 SFS(ph)LEGLTGGAGVGNKPSSSLEVSSANAEELR ddPTM_PC-9_AZD4547_30min_R2 1 SFSLEGLTGGAGVGNKPSSSLEVSSANAEELR 32 1 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36;H0YMW2;H0YLH1 Q12802-2 AKAP13 A-kinase anchor protein 13 1 S(0.039)FS(0.957)LEGLT(0.004)GGAGVGNKPSSSLEVSSANAEELR 72.943 4.6358e-06 13619000.0 15355.0 18312.0 15485.0 20746.0 23173.0 22443.0 19795.0 25941.0 25689.0 20252.0 True False 20237.57059615909 24230.9958893226 15279.658782280745 15963.330222504866 19955.82894509617 21039.63566214374 21556.716652003775 21932.414514877637 27046.868094867066 19542.98364422904 1.0355414999354593 1.2398821147495516 0.781848824132479 0.816831785417718 1.0211249883018267 1.076582575371323 1.1030412266844107 1.122265408094643 1.3839682101383681 1.0 14.254363121171576 -7.208418590695002 1.5008669566508024 1.1833610597047768 0.9752059230661385 0.239503619825009 0.14734794019562283 0.6087754219142608 2.69155715021205 0.0879189536441183 0.05474741630787062 6.18844320195371e-08 7.208418590695002 -0.20815513663863827 SFS(ph)LEGLTGGAGVGNKPSSSLEVSSANAEELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFSLEGLTGGAGVGNKPSSSLEVSSANAEELR 32 1 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36;H0YMW2;H0YLH1 Q12802-2 AKAP13 A-kinase anchor protein 13 1 S(0.069)FS(0.88)LEGLT(0.051)GGAGVGNKPSSSLEVSSANAEELR;S(0.282)FS(0.714)LEGLT(0.003)GGAGVGNKPSSSLEVSSANAEELR 94.88600000000001 5.1332e-13 12047800.0 27437.1 33595.6 32193.5 30739.5 35956.6 21727.2 27241.2 20174.8 23690.9 24927.6 True False 32081.659122573517 36930.74914241448 32961.11513452866 29017.26547380363 28911.16234661282 20587.787383450384 24660.716326791142 19645.232876967548 24037.33459372056 29446.776553226966 1.089479490720617 1.2541525241535265 1.119345442614043 0.9854139865310226 0.9818107694862291 0.6991524979393455 0.8374674315273624 0.667143748024763 0.8162976531666042 1.0 14.845822094922676 -6.184537284373088 1.337075498564602 0.7871599232099555 1.1732532075214654 0.6779145621023948 0.10130483361347346 0.22224481046593814 0.8035538507786444 0.03677155377620443 0.05591402625608297 6.538267962759845e-07 6.184537284373088 0.3860932843115099 SFS(ph)LEGLTGGAGVGNKPSSSLEVSSANAEELR ddPTM_PC-9_Lapatinib_30min_R1 1 SFSLEGLTGGAGVGNKPSSSLEVSSANAEELR 32 1 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36;H0YMW2;H0YLH1 Q12802-2 AKAP13 A-kinase anchor protein 13 1 S(0.221)FS(0.741)LEGLT(0.038)GGAGVGNKPSSSLEVSSANAEELR 80.667 1.3232e-07 7233000.0 9604.3 14409.0 16477.0 12342.0 13633.0 16089.0 16568.0 13364.0 12056.0 12676.0 True False 9467.340920787088 14375.636845786317 15122.324663059317 13249.671851705058 12831.133743509256 15400.91097529083 17425.809972153398 13984.940227680585 10698.126324691817 14867.0297102917 0.6368011031977237 0.9669474754486288 1.0171718869029291 0.8912117692569737 0.8630596691837445 1.0359104189204351 1.1721110613030108 0.9406680756142911 0.7195873374280028 1.0 13.859828819120226 -4.760760284099483 24.96031194704125 0.9606292691106458 0.6368007229110827 0.41735629786925554 0.11314465268633382 16.925220733261416 621630.6157707126 0.029511962153833726 0.17134798847216035 1.7347612632255803e-05 4.760760284099483 -0.32382854619956314 SFS(ph)LPADPILQAAK ddPTM_PC-9_AZD4547_30min_R2 1 SFSLPADPILQAAK 14 0 B7ZBB8 B7ZBB8 PPP1R3G Protein phosphatase 1 regulatory subunit 3G 1 S(0.001)FS(0.999)LPADPILQAAK 145.86 0.00018933 35316000.0 138570.0 127820.0 161920.0 210290.0 181590.0 148950.0 130010.0 193550.0 146360.0 162610.0 True False 182632.377564947 169135.315343666 159772.83500335162 161810.88944811272 156379.36297156263 139636.1329535405 141580.63813725716 163641.2948365351 154096.29080013797 156917.0733946322 1.1638783059995208 1.0778643246697956 1.0181991770999796 1.031187275849665 0.9965732828720475 0.8898721466871122 0.9022640753769012 1.042852070182268 0.982023736911023 1.0 17.259642808015542 -4.68050955275331 0.7767113113474807 0.966291028711352 1.303149208089184 0.6495287489875027 0.04468683287891266 2.0730088468355894 0.8588449445743415 0.01922218555263022 0.6300147840208739 2.086846221082906e-05 4.68050955275331 0.336858179377832 SFS(ph)LPADPILQAAK ddPTM_PC-9_Lapatinib_30min_R1 2 SFSLPADPILQAAK 14 0 B7ZBB8 B7ZBB8 PPP1R3G Protein phosphatase 1 regulatory subunit 3G 1 S(0.153)FS(0.847)LPADPILQAAK;S(0.003)FS(0.997)LPADPILQAAK 174.24 2.9224e-05 47018000.0 267986.0 200399.0 247852.0 190600.0 190799.0 211225.0 187944.0 155691.0 209345.0 175400.0 True False 264164.4704973867 199934.98842797833 227474.56529638747 204617.35982296147 179576.57794526673 202191.39913952406 197674.82070294544 162924.97223793936 185766.36159941996 205717.65629419097 1.284111802827525 0.9718902695549719 1.105761019224731 0.9946514242333386 0.872927395636179 0.9828587530200903 0.9609035231290809 0.7919834163624001 0.9030161287359836 1.0 17.65030609695745 -1.5228787453225163 0.5029677249022223 0.907323731515511 11.691407812667487 0.623514678154714 0.07800739893433194 72.01832990154162 0.7590111512849089 0.0425704871701522 821.8123329436186 0.029999999997086396 1.5228787453225163 10.784084081151976 SFS(ph)LSSNFTTPEEVPTGTK ddPTM_PC-9_Lapatinib_30min_R1 1 SFSLSSNFTTPEEVPTGTK 19 0 P17029;E9PC66;B3KRF7 P17029 ZKSCAN1 Zinc finger protein with KRAB and SCAN domains 1 1 S(0.006)FS(0.593)LS(0.102)S(0.298)NFTTPEEVPTGTK 230.99 9.0177e-36 3145800.0 27921.0 22927.0 22740.0 17217.0 27441.0 29767.0 31489.0 24824.0 31197.0 28471.0 True False 27522.84141991568 22873.913940130682 20870.40497893846 18483.19561422832 25826.974331081736 28493.934800266135 33119.34634313967 25977.41366446745 27683.265341026112 33392.17441477716 0.8242302845584053 0.685008219470973 0.6250088634450413 0.5535187791199631 0.7734439216289081 0.8533117504218776 0.9918295805403808 0.7779491488572117 0.829034521596633 1.0 15.027222420697596 -6.603131687144466 3.3339063143843575 0.8833278166542157 0.6686939381589009 0.5654437600127545 0.08993048700401599 0.19275555740768377 4.296358998098983 0.032149007454479656 0.03252656870591131 2.4938384284635414e-07 6.603131687144466 -0.2146338784953148 SFS(ph)MHDLTTIQGDEPVGQRPYQPLPEAK ddPTM_PC-9_AZD4547_30min_R2 1 SFSMHDLTTIQGDEPVGQRPYQPLPEAK 28 1 Q6NUK4 Q6NUK4 REEP3 Receptor expression-enhancing protein 3 1 S(0.022)FS(0.349)MHDLT(0.315)T(0.315)IQGDEPVGQRPY(0.001)QPLPEAK 50.945 0.021169999999999998 10208000.0 15727.0 13755.0 25709.0 24188.0 19501.0 18561.0 21639.0 18592.0 12849.0 15895.0 True False 20727.85885807841 18201.034756314573 25368.081862037798 18611.83030087476 16793.622761762417 17400.377735821858 23564.829079702424 15719.033601657797 13528.171908246602 15338.52088806146 1.3513596916774206 1.1866225491456035 1.6538805825653449 1.2134045020834467 1.0948658533844366 1.1344234468764989 1.536316914236744 1.0248076536436121 0.8819736927030611 1.0 13.904871748287103 -7.93378738838059 8.148054957397576 0.9449426814756278 1.2994492256500227 0.4693132059741988 0.16754600532691707 0.22383087331136725 24.238704568885936 0.09467314937931133 0.04522171120505935 1.164696074218236e-08 7.93378738838059 0.354506544174395 SFS(ph)MHDLTTIQGDEPVGQRPYQPLPEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFSMHDLTTIQGDEPVGQRPYQPLPEAK 28 1 Q6NUK4 Q6NUK4 REEP3 Receptor expression-enhancing protein 3 1 S(0.019)FS(0.327)MHDLT(0.327)T(0.327)IQGDEPVGQRPYQPLPEAK;S(0.008)FS(0.567)MHDLT(0.212)T(0.212)IQGDEPVGQRPYQPLPEAK 73.831 5.9121000000000005e-05 28026000.0 37905.0 44845.0 39139.0 46767.0 60258.0 43163.0 45509.0 38767.0 42624.0 31309.0 True False 44321.567842124336 49296.91522971991 40072.22219548405 44146.796610659694 48450.87746567239 40899.456295881144 41198.05806337235 37749.4073270318 43247.29536331436 36985.07385809235 1.1983636429166344 1.3328867590981903 1.083470114166508 1.1936381898288506 1.3100116455512043 1.1058368154896174 1.1139103904846792 1.0206659981773218 1.1693175341287534 1.0 15.174655536356996 -6.909495465411158 7.5295115369033265 1.0822156178375006 1.2200568085008892 0.45865302522613405 0.0773409550252259 0.22722646700217977 16.29136401234613 0.026991476700321444 0.023799740243736035 1.2316988461776422e-07 6.909495465411158 0.1378411906633885 SFS(ph)MHDLTTIQGDEPVGQRPYQPLPEAK ddPTM_PC-9_Lapatinib_30min_R1 1 SFSMHDLTTIQGDEPVGQRPYQPLPEAK 28 1 Q6NUK4 Q6NUK4 REEP3 Receptor expression-enhancing protein 3 1 S(0.034)FS(0.438)MHDLT(0.264)T(0.264)IQGDEPVGQRPYQPLPEAK 50.055 0.025502 9037100.0 42029.0 47954.0 36517.0 23464.0 26304.0 27706.0 28963.0 26685.0 33808.0 13451.0 True False 41429.658752825366 47842.965459284955 33514.71321969637 25189.620833609424 24756.85043565375 26521.0789658405 30462.562422952615 27924.88251838195 30000.1870259772 15775.987427669112 2.626121435680338 3.032644750678133 2.124413027923422 1.596706447003753 1.5692742244604814 1.6811042153422258 1.9309448972762926 1.77008777716222 1.9016360886140553 1.0 13.945442686653859 -5.468905413733788 3.461248709263245 1.6828928288812788 2.821813322862425 0.7608492228405959 0.26480857484341674 0.10740718008013805 2.549730063314842 0.06922332714946583 0.15160895357259402 3.396992486279034e-06 5.468905413733788 1.1389204939811461 SFS(ph)MQDLR ddPTM_PC-9_AZD4547_30min_R2 3 SFSMQDLR 8 0 E5RGS2;Q9H6H4 E5RGS2 REEP4 Receptor expression-enhancing protein;Receptor expression-enhancing protein 4 1 S(0.004)FS(0.996)MQDLR;S(0.011)FS(0.989)MQDLR;S(0.002)FS(0.998)MQDLR 95.48299999999999 0.0064128 97050000.0 131304.0 145887.0 244493.0 225015.0 164715.0 135287.0 167600.0 199633.0 146015.0 131054.0 True False 173055.94070713624 193042.11977422482 241250.86307111176 173141.26819709508 141847.1654378595 126827.48250342814 182516.07531577867 168784.30695996896 153733.05480446958 126465.83934973284 1.3684006811401581 1.5264368683813478 1.9076365942896927 1.3690753889537273 1.1216243545863056 1.0028596113824477 1.4432045543227103 1.3346237041388485 1.2156093344648675 1.0 16.948388214642627 -5.993410686705132 24.912967103171376 1.2102341769293354 1.6008810194105891 0.5177641626605534 0.1784710580923677 138.60612865640522 524036.32514449995 0.05205273377021154 0.07699428927549741 1.0152881405944388e-06 5.993410686705132 0.3906468424812537 SFS(ph)MQDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SFSMQDLR 8 0 E5RGS2;Q9H6H4 E5RGS2 REEP4 Receptor expression-enhancing protein;Receptor expression-enhancing protein 4 1 S(0.007)FS(0.993)MQDLR;S(0.002)FS(0.998)MQDLR;S(0.004)FS(0.996)MQDLR;S(0.058)FS(0.942)MQDLR;S(0.102)FS(0.898)MQDLR;S(0.037)FS(0.963)MQDLR 80.24 0.017241 163544000.0 401902.0 442803.0 399645.0 415712.0 572192.0 386693.0 460900.0 355315.0 368242.0 293935.0 True False 469936.0706736694 486761.5554569229 409174.0524621024 392421.00439648866 460075.0851146412 366414.13834587845 417240.2153729665 345988.3577373614 373626.84260458004 347223.08871182083 1.3534125061127333 1.4018697813638556 1.1784183303596438 1.130169672334722 1.3250129385735703 1.055270085020139 1.201648821571473 0.9964439836675602 1.0760426214475418 1.0 18.405503357883205 -1.522878747996445 0.18455363004828634 0.9690031146524152 2.8518950701716896 0.6481560760861012 0.08284595015113118 33.60867861891119 0.38523341248889403 0.17569855496808504 17.86963516114783 0.02999999981237795 1.522878747996445 1.8828919555192745 SFS(ph)MQDLR ddPTM_PC-9_Lapatinib_30min_R1 8 SFSMQDLR 8 0 E5RGS2;Q9H6H4 E5RGS2 REEP4 Receptor expression-enhancing protein;Receptor expression-enhancing protein 4 1 S(0.004)FS(0.996)MQDLR;S(0.009)FS(0.991)MQDLR;S(0.009)FS(0.991)MQDLR;S(0.003)FS(0.997)MQDLR;S(0.052)FS(0.948)MQDLR;S(0.02)FS(0.98)MQDLR;S(0.001)FS(0.999)MQDLR;S(0.001)FS(0.999)MQDLR 126.03 0.0033788000000000004 158367410.0 673904.0 895778.0 578394.3 316271.1 427447.7 490024.5 528180.2 472657.8 566805.8 219730.9 True False 664294.0053811434 893703.8810774363 530840.9533205633 339530.73174346087 402306.06668051163 469067.2944379012 555526.7863504337 494619.2069101333 502966.16207432 257711.0932919799 2.5776694239099585 3.4678518090212487 2.0598296586291474 1.3174859002238661 1.5610739201851487 1.8201284564279903 2.155618445656262 1.9192779037638972 1.9516667119349518 1.0 17.975395114439415 -5.419691563106917 5.129759815895036 1.731183737420288 3.006345711194652 0.6642885612952871 0.37607453872412766 0.1269295644909036 5.025123806129383 0.09828998587802538 0.2095867428479379 3.8045950356728354e-06 5.419691563106917 1.275161973774364 SFS(ph)PEER ddPTM_PC-9_AZD4547_30min_R2 3 SFSPEER 7 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(0.014)FS(0.986)PEER;S(0.002)FS(0.998)PEER;S(0.009)FS(0.991)PEER 99.13600000000001 0.011939 144361000.0 616801.0 608762.0 906694.0 1108410.0 949678.0 897546.0 650737.0 980965.0 758857.0 840919.0 True False 812930.8877422023 805532.4115102555 894670.6451366638 852883.1992637923 817831.6023355223 841422.3067332562 708651.3323553922 829379.399583166 798968.6317827291 811478.6817658227 1.0017895799470906 0.992672302564218 1.1025189758402658 1.0510235431051262 1.007828820044755 1.0369000759234668 0.8732839793318138 1.0220593814964927 0.9845836369282418 1.0 19.630193668883855 SFS(ph)PEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFSPEER 7 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(0.015)FS(0.985)PEER;SFS(1)PEER 134.77 0.0039603 58346000.0 315550.0 328990.0 347080.0 362960.0 453100.0 381960.0 412770.0 352860.0 381240.0 325990.0 True False 368966.3826034122 361649.9529808352 355355.70350823045 342624.52793219703 364318.3076055646 361929.34519784915 373669.4374039898 343597.7988860739 386814.9137647797 385089.4064645808 0.9581317387845321 0.939132437583942 0.9227875333436752 0.8897272222514655 0.9460616196905779 0.9398579631692314 0.9703446294058432 0.8922546118330494 1.0044807965922522 1.0 18.554833910604096 -8.283378196356182 24.524240547241906 1.002240441840691 0.9327601562693633 0.5691245981448096 0.024343888652616254 529.523988036567 591919.5851716552 0.02339780672111943 0.006061830220854578 5.207410370488294e-09 8.283378196356182 -0.06948028557132768 SFS(ph)PEER ddPTM_PC-9_Lapatinib_30min_R1 2 SFSPEER 7 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(0.001)FS(0.999)PEER;S(0.004)FS(0.996)PEER 106.68 0.010019 40878000.0 112106.0 124923.0 134655.0 108586.0 129477.0 126930.0 115157.0 119263.0 139985.0 101019.0 True False 110507.34788227765 124633.74846874595 123584.18568333138 116571.77667227713 121861.41742157616 121501.4997882818 121119.26599247142 124804.39437098714 124218.41519259996 118479.99955064352 0.9327088816795782 1.0519391369129103 1.0430805718437406 0.983894134996593 1.0285399888905913 1.025502196565647 1.0222760504037627 1.053379429813724 1.0484336230901452 1.0 16.854284014704533 -4.752997412035793 24.999916232645706 1.0289939933630974 0.9327087022234156 0.6410223292723745 0.021516601431927653 211.0772271806934 625033.6970516973 0.005485855949335444 0.0620711251869662 1.7660483445506775e-05 4.752997412035793 -0.09628529113968176 SFS(ph)PLQPGQAPTGR ddPTM_PC-9_AZD4547_30min_R2 3 SFSPLQPGQAPTGR 14 0 Q7Z3C6;H7C152;Q7Z3C6-2;H7C1G6 Q7Z3C6 ATG9A Autophagy-related protein 9A 1 S(0.23)FS(0.77)PLQPGQAPTGR;S(0.003)FS(0.979)PLQPGQAPT(0.018)GR;S(0.017)FS(0.983)PLQPGQAPTGR 127.57 2.8379e-05 18381300.0 45760.0 46438.0 71987.0 87846.0 70200.0 61088.0 59416.0 73573.0 58787.0 66464.0 True False 60310.72813287142 61448.17535541521 71032.4053445298 67594.46190717057 60453.94174020411 57268.15770302707 64703.908895956374 62203.983389348585 61894.36080396084 64137.1155900671 0.9403405123228169 0.9580751299787431 1.1075085727043605 1.0539055472840582 0.9425734410414708 0.8929019831365191 1.0088372122861269 0.9698593835576557 0.9650318732691248 1.0 15.968871853106412 -6.2734175364419 24.41621445036348 0.9604605117566457 1.0175052149739656 0.18608683361759193 0.05273417485289716 958.8244255982619 1954458.2898284253 0.0176558990413149 0.02017160868361227 5.328223866918988e-07 6.2734175364419 0.057044703217319914 SFS(ph)PLQPGQAPTGR ddPTM_PC-9_Lapatinib_30min_R1 1 SFSPLQPGQAPTGR 14 0 Q7Z3C6;H7C152;Q7Z3C6-2;H7C1G6 Q7Z3C6 ATG9A Autophagy-related protein 9A 1 S(0.007)FS(0.993)PLQPGQAPTGR 75.998 0.016821 5293100.0 14847.0 16606.0 15772.0 11091.0 12854.0 11720.0 11687.0 9835.3 15371.0 8381.7 True False 14635.279057393656 16567.549827269606 14475.28704168062 11906.669138491403 12097.952991936327 11218.76292065439 12292.095675069824 10292.283943527898 13639.756116194252 9830.465677086773 1.4887676268995198 1.6853270609433983 1.4724925061709107 1.2112009267520178 1.2306591965561409 1.1412239551177634 1.2504082796118918 1.046978269556197 1.3874984730363609 1.0 13.263044044474222 -5.684779921102426 3.027934907390244 1.18259154440618 1.5883398949799084 0.7046557357116876 0.11073335895619366 0.12380292749147728 2.2764493375528465 0.029084414925410945 0.0539751859251192 2.066427053243018e-06 5.684779921102426 0.40574835057372827 SFS(ph)QPGLR ddPTM_PC-9_AZD4547_30min_R2 1 SFSQPGLR 8 0 C9JIE2;Q86TI0-2;Q86TI0 C9JIE2 TBC1D1 TBC1 domain family member 1 1 S(0.075)FS(0.925)QPGLR 99.973 0.0050353 19623000.0 46778.0 46067.0 79410.0 93347.0 68838.0 60258.0 61462.0 79977.0 56248.0 68023.0 True False 61652.430957155986 60957.2568607156 78356.97151442764 71827.29134677336 59281.03193037281 56490.05773423597 66931.99893232917 67618.3923386286 59221.1544474321 65641.5354745898 0.9392289578756424 0.9286384972562456 1.1937102163729865 1.0942353926894064 0.9031024564213741 0.8605840391424663 1.019659251545676 1.0301159448776769 0.9021902674771668 1.0 16.00232136604987 -6.26235210196244 24.9996383134267 0.9528657560858048 1.0421277070535768 0.19149910204728526 0.08681666471778983 154.46015832180964 4230693.540807698 0.028680865740229534 0.03444552657255901 5.465726523150088e-07 6.26235210196244 0.08926195096777201 SFS(ph)QPGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SFSQPGLR 8 0 C9JIE2;Q86TI0-2;Q86TI0 C9JIE2 TBC1D1 TBC1 domain family member 1 1 S(0.005)FS(0.995)QPGLR;S(0.003)FS(0.997)QPGLR 106.88 0.003819 36240000.0 71486.0 73025.0 70515.0 82930.0 83134.0 63491.0 79678.0 68968.0 81762.0 58744.0 True False 83587.16788714149 80274.43939458801 72196.34502962683 78283.70096268757 66844.48948241255 60161.42019048234 72130.32302123481 67157.66307763621 82957.61457149265 69393.82218275194 1.2045332748354844 1.156795185357876 1.0403857686278515 1.1281076398490302 0.9632628291661813 0.8669564277933037 1.0394343581662957 0.9677758187288388 1.1954610938279175 1.0 16.08251961147367 -5.219647502997932 1.0801011076554887 1.0066867740261134 1.235411810436383 0.36616570072514454 0.08449762949033571 1.0384024901253137 1.6055709697830263 0.029183725897815503 0.2300574899999138 6.030488547105275e-06 5.219647502997932 0.22872503641026953 SFS(ph)QPGLR ddPTM_PC-9_Lapatinib_30min_R1 2 SFSQPGLR 8 0 C9JIE2;Q86TI0-2;Q86TI0 C9JIE2 TBC1D1 TBC1 domain family member 1 1 S(0.419)FS(0.581)QPGLR;S(0.06)FS(0.94)QPGLR 82.831 0.015913999999999998 38443000.0 111166.0 107363.0 120599.0 93023.0 85562.0 103062.0 89605.0 79347.0 118446.0 79678.0 True False 109580.7524546521 107114.40756986318 110683.8157456025 99864.22173563125 80529.4113813643 98654.27850925621 94244.30845936769 83033.75129046485 105105.3641883252 93450.23613573867 1.172610760399615 1.1462186934902656 1.1844145111076192 1.068635306502341 0.8617357720144595 1.055687846159731 1.0084972746615173 0.8885344192159811 1.1247201562514746 1.0 16.511910689014037 -5.967479570176022 5.023009621791628 0.9863626282280239 1.1625559922720923 0.5545591732416062 0.07127471383281161 0.13449285863805857 8.560552291472503 0.01965310683617671 0.028963971686729872 1.0777559516594629e-06 5.967479570176022 0.17619336404406838 SFS(ph)SPENFQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFSSPENFQR 10 0 G3V1T9;J3KPD3;Q9Y580;I3L521;F5GXV8;F5GY08 G3V1T9 RBM7 RNA-binding protein 7 1 S(0.001)FS(0.798)S(0.201)PENFQR 143.0 0.00012795 5425100.0 27967.0 32903.0 40210.0 31684.0 46276.0 34731.0 31334.0 31486.0 33679.0 24358.0 True False 32701.260726571472 36169.39239164842 41168.75889727417 29908.848200913944 37208.54999504556 32909.64521956881 28365.816681485165 30659.525862174585 34171.4916605918 28773.912582178098 1.1364898893460142 1.2570203057491358 1.4307668023838078 1.0394432149432051 1.2931348800333704 1.1437320220383338 0.9858171564424054 1.06553204311757 1.1875858579537368 1.0 14.812473786901124 -6.990033930252725 6.304740955156581 1.0647425249943374 1.2324066545777146 0.3614183743154774 0.10752833758051276 0.17316069009143029 29.161682625072856 0.038931414055667905 0.033083085832449656 1.0232130482911134e-07 6.990033930252725 0.16766412958337717 SFS(ph)SSAEEHS ddPTM_PC-9_AZD4547_30min_R2 2 SFSSSAEEHS 10 0 Q96EQ0 Q96EQ0 SGTB Small glutamine-rich tetratricopeptide repeat-containing protein beta 1 S(0.003)FS(0.946)S(0.026)S(0.026)AEEHS;S(0.013)FS(0.984)S(0.002)S(0.002)AEEHS 156.83 0.00012603 24513000.0 81972.0 66262.0 152739.0 202786.0 141439.0 142893.0 92971.0 143302.0 109076.0 113760.0 True False 108037.39087648019 87679.89567596621 150713.58106211032 156036.8207124684 121802.63626485395 133957.87812104935 101245.23889130792 121157.96865236497 114841.53467693257 109777.29702584929 0.9841505830758486 0.7987070009140433 1.372903005861237 1.421394267666532 1.1095430436420115 1.2202694159021445 0.9222784822937267 1.1036705396730244 1.0461319215200826 1.0 16.744220196768545 -7.250215016191929 24.632626321192454 1.0266594422935922 1.1556113267545276 0.12354434554991878 0.17287414467596923 1538.7236930545887 3376838.2200281196 0.07336397530975446 0.05631500190130565 5.620629828009922e-08 7.250215016191929 0.12895188446093542 SFS(ph)SSAEEHS ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFSSSAEEHS 10 0 Q96EQ0 Q96EQ0 SGTB Small glutamine-rich tetratricopeptide repeat-containing protein beta 1 S(0.155)FS(0.823)S(0.011)S(0.011)AEEHS 125.97 0.00036178 6687800.0 5882.7 10766.0 17803.0 14307.0 38775.0 44875.0 49932.0 55884.0 54754.0 38690.0 True False 6878.5249213788375 11834.777329984716 18227.491038253473 13505.425173919824 31177.3170986665 42521.676002077395 45202.07948362538 54417.104213992454 55554.673665608956 45704.190730128495 0.15050096744945687 0.25894293588669004 0.39881443576765474 0.29549642949955923 0.6821544501851164 0.9303671134482386 0.9890138904445774 1.190637080422482 1.2155269085420424 1.0 15.480038835169376 -6.587409763423872 1.072846770823592 1.145145754691097 0.22783509123055393 0.9528072648462426 0.08365766221327665 0.09575788070293731 0.23571447455568706 0.0421200973142417 0.045455541059719926 2.5857720487307386e-07 6.587409763423872 -0.9173106634605431 down SFS(ph)SSAEEHS ddPTM_PC-9_Lapatinib_30min_R1 2 SFSSSAEEHS 10 0 Q96EQ0 Q96EQ0 SGTB Small glutamine-rich tetratricopeptide repeat-containing protein beta 1 S(0.118)FS(0.823)S(0.03)S(0.03)AEEHS;S(0.012)FS(0.953)S(0.012)S(0.023)AEEHS 175.93 0.00049493 14516600.0 24820.0 25805.8 31347.0 28038.0 83058.0 155184.0 142669.0 125689.0 187922.0 141477.0 True False 24466.062248569437 25746.04825560363 28769.770662919243 30100.008052026118 78172.69173831075 148547.14207157277 150055.70273522154 131528.96979025306 166756.24545361125 165931.11094374734 0.1474471068711384 0.15516106719933825 0.17338382476492034 0.1814006299411229 0.4711153399365369 0.8952338185810861 0.9043253063380757 0.7926721459415949 1.0049727534828814 1.0 17.340224881504035 -6.571384660470503 2.208447669624386 0.9156942488204665 0.15910178254358073 0.97385313554963 0.058523373068798894 0.04497531137246815 0.44440850037920476 0.021485618082793947 0.022410208085404285 2.682967052923965e-07 6.571384660470503 -0.7565924662768857 down SFS(ph)TTSASSQK ddPTM_PC-9_Lapatinib_30min_R1 1 SFSTTSASSQK 11 0 B5MCH3;Q8N3C7;Q8N3C7-3;Q8N3C7-2 B5MCH3 CLIP4 CAP-Gly domain-containing linker protein 4 1 S(0.074)FS(0.9)T(0.025)T(0.001)SASSQK 127.56 0.00035422 41356000.0 66317.0 50235.0 60576.0 53461.0 78764.0 68192.0 79638.0 72748.0 63382.0 65295.0 True False 65371.30741895168 50118.6839439292 55595.675110122094 57392.700280667974 74131.25637598209 65275.58712331613 83761.26596827323 76128.13765963088 56243.251717950996 76581.15374988147 0.8536213443905297 0.6544519309231062 0.7259707171780255 0.7494363491586441 0.9680091347030251 0.8523714246524676 1.093758214218637 0.9940844964058629 0.7344268003802181 1.0 16.224701775134413 -6.253543500672601 19.514226433139495 0.9434082192226284 0.7379184437482734 0.47132732169398217 0.10078254072338426 26.16094794162099 64652.34089721337 0.029906445896369142 0.037624981393322855 5.577717306953121e-07 6.253543500672601 -0.20548977547435499 SFSAS(ph)QSTDREGASPVTEVR ddPTM_PC-9_AZD4547_30min_R2 1 SFSASQSTDREGASPVTEVR 20 1 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 SFS(0.01)AS(0.519)QS(0.169)T(0.289)DREGAS(0.009)PVT(0.003)EVR 68.033 0.025443 4064800.0 11630.0 3937.9 11462.0 28134.0 18907.0 9342.7 9729.7 14430.0 7269.4 17481.0 True False 15328.09808097235 5210.749165168382 11310.006390862245 21648.14096596703 16282.089408576061 8758.499492078168 10595.62445107356 12200.17506841232 7653.645643225765 16868.995510802295 0.9086550572117225 0.30889504723808875 0.6704611654926178 1.2833094271739147 0.9652079993826307 0.5192069371569601 0.6281123522908346 0.7232306784716238 0.45371081154919074 1.0 14.042086448330243 -5.5273489001043155 24.999772605261306 0.7887639347386243 0.5790007336885125 0.07578780651949224 0.26776530602362575 299.6865806461397 1676021.2941223541 0.07611496256464259 0.13249539938135252 2.9692796366324976e-06 5.5273489001043155 -0.2097632010501118 SFSEDT(ph)LMDGPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFSEDTLMDGPAR 13 0 Q9BRG2;M0QZQ6 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 S(0.047)FS(0.103)EDT(0.85)LMDGPAR 122.52 0.00068987 40743000.0 100240.0 106550.0 93357.0 109770.0 118810.0 108040.0 110970.0 97971.0 73924.0 72500.0 True False 117208.65216975452 117127.57983558178 95582.98493839399 103619.94277914162 95530.03338472142 102374.19220645002 100458.11824677399 95399.36505885495 75004.99864953208 85643.67609031578 1.3685616676023085 1.3676150438949464 1.1160542062393104 1.2098960192912425 1.115435928789184 1.195350280136166 1.17297765384143 1.1139102081308523 0.8757797665111355 1.0 16.38605910151582 -1.5228787452986898 0.1830037510311175 0.954687751862758 2.8039152746742584 0.6734267497591649 0.08132448687492372 35.51760029063749 0.40478463979730844 0.18545375273043058 18.346975632630098 0.02999999999873227 1.5228787452986898 1.8492275228115003 SFSEDT(ph)LMDGPAR ddPTM_PC-9_Lapatinib_30min_R1 6 SFSEDTLMDGPAR 13 0 Q9BRG2;M0QZQ6 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 SFS(0.003)EDT(0.997)LMDGPAR;S(0.005)FS(0.11)EDT(0.885)LMDGPAR;SFS(0.023)EDT(0.977)LMDGPAR;S(0.005)FS(0.258)EDT(0.737)LMDGPAR;SFSEDT(1)LMDGPAR;S(0.261)FS(0.082)EDT(0.656)LMDGPAR 151.7 0.00015642 123364200.0 413749.0 414285.0 441833.0 361064.0 415135.0 418299.0 369588.0 364329.0 443225.0 336139.0 True False 407848.86338772596 413325.7485360943 405507.19626470114 387617.851034195 390717.57548681204 400409.3268725943 388723.4582320275 381257.05538840534 393304.33313383645 394240.17827293684 1.034518767656826 1.0484110228104258 1.0285790708626457 0.9832023025462485 0.9910648305772476 1.0156481985846366 0.9860067026524879 0.9670679864710716 0.9976262055704214 1.0 18.588715287960063 -5.6497828092892295 4.403931440836561 0.9909471270410967 1.0408060107757666 0.7463172373924887 0.012309603233624669 0.1057077788218976 3.54492469732478 0.0035913769570800162 0.006411549187003341 2.23984100321671e-06 5.6497828092892295 0.049858883734669956 SFSKEELMS(ph)SDLEETAGSTSIPK ddPTM_PC-9_AZD4547_30min_R2 5 SFSKEELMSSDLEETAGSTSIPK 23 1 O00567 O00567 NOP56 Nucleolar protein 56 1 SFS(0.001)KEELMS(0.499)S(0.499)DLEET(0.001)AGSTSIPK;SFSKEELMS(0.499)S(0.499)DLEET(0.002)AGSTSIPK;SFSKEELMS(0.497)S(0.497)DLEET(0.005)AGSTSIPK;SFSKEELMS(0.5)S(0.5)DLEETAGSTSIPK;SFSKEELMS(0.5)S(0.5)DLEETAGSTSIPK 96.44 1.0320999999999998e-05 32938000.0 141123.0 135261.2 169530.0 266376.0 213263.0 188842.0 135596.0 181803.0 131565.0 199673.0 True False 185997.17845924848 178981.73772306924 167281.92143106597 204967.1286681748 183655.1136373382 177033.679887294 147663.78131574148 153709.5237673294 138519.257304729 192682.50904573122 0.9653039052709447 0.9288945769363516 0.8681738797129911 1.0637557590633613 0.9531488589540296 0.9187843814369102 0.7663579950616846 0.7977347011339158 0.7188989700764841 1.0 17.555866089878045 -7.121984424730804 4.305630264830991 0.8044978464176405 0.9540311260732143 0.37082908124501757 0.08212085810946737 0.22510445523259584 6.841170244777425 0.03128946732878606 0.02403617460112135 7.551193083125453e-08 7.121984424730804 0.14953327965557373 SFSKEELMS(ph)SDLEETAGSTSIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SFSKEELMSSDLEETAGSTSIPK 23 1 O00567 O00567 NOP56 Nucleolar protein 56 1 S(0.001)FS(0.001)KEELMS(0.495)S(0.495)DLEET(0.006)AGS(0.001)T(0.001)SIPK;S(0.001)FS(0.001)KEELMS(0.418)S(0.418)DLEET(0.118)AGS(0.024)T(0.016)S(0.004)IPK;S(0.005)FS(0.022)KEELMS(0.484)S(0.484)DLEET(0.003)AGS(0.001)TSIPK 67.979 0.0047989 43437000.0 67737.0 47444.0 66446.0 98858.0 96166.0 99684.0 93395.0 106714.0 89805.0 62463.0 True False 79203.53623326673 52153.92677352727 68030.32463785826 93319.30676196041 77322.96263340718 94456.39555634721 84547.94947875474 103912.87057282942 91118.22823063159 73787.04744316396 1.0734070406364333 0.7068168273530655 0.9219819330792448 1.264711219592322 1.047920540430444 1.280121631497781 1.1458372764390607 1.4082806423833467 1.2348810717872583 1.0 16.171079967792608 -5.702577653968774 5.772767210561242 1.20940997800796 0.8747709738880453 0.4891632700404783 0.1382038819967471 0.14661070931484482 9.769425624092209 0.03642584722416717 0.06313999107927028 1.983454973717383e-06 5.702577653968774 -0.33463900411991465 SFSKEELMS(ph)SDLEETAGSTSIPK ddPTM_PC-9_Lapatinib_30min_R1 4 SFSKEELMSSDLEETAGSTSIPK 23 1 O00567 O00567 NOP56 Nucleolar protein 56 1 S(0.007)FS(0.007)KEELMS(0.493)S(0.493)DLEETAGSTSIPK;S(0.007)FS(0.006)KEELMS(0.493)S(0.493)DLEET(0.001)AGSTSIPK;SFS(0.001)KEELMS(0.918)S(0.077)DLEET(0.004)AGSTSIPK;S(0.001)FS(0.001)KEELMS(0.322)S(0.322)DLEET(0.238)AGS(0.09)T(0.022)S(0.006)IPK 88.071 0.00021803 23079600.0 140784.0 103659.2 139091.1 98327.0 102377.7 121928.8 100929.7 92761.2 131399.9 83868.1 True False 138776.39434337633 103419.18349120226 127655.56666517281 105558.29558925646 96356.04496830257 116714.18945391508 106155.3460131851 97071.22399340954 116600.25955971064 98364.58933778117 1.4108369208640945 1.0513863188719648 1.2977796941418345 1.073133088847373 0.9795806155141733 1.1865468075419083 1.0792028587508324 0.9868513115026561 1.1853885666040722 1.0 16.58585142701292 -1.522884785686331 0.9031861298507872 1.081727095674978 150.83857447287662 0.4497746960351787 0.10090650343385543 878.7247446881514 1.909526603520558 0.03255107766119545 271280.487071386 0.029999582746437818 1.522884785686331 149.75684737720164 SFSKEELMSS(ph)DLEETAGSTSIPK ddPTM_PC-9_AZD4547_30min_R2 2 SFSKEELMSSDLEETAGSTSIPK 23 1 O00567 O00567 NOP56 Nucleolar protein 56 1 SFSKEELMS(0.223)S(0.775)DLEET(0.001)AGSTSIPK;SFSKEELMS(0.056)S(0.943)DLEET(0.001)AGSTSIPK 103.04 0.00014155 11542000.0 103845.0 85029.0 113726.0 171412.0 146688.0 127529.0 94069.0 110374.0 89951.0 142388.0 True False 136865.5498898169 112512.96141727881 112217.91893275158 131895.6116890004 126322.90321918906 119554.59146983617 102440.95876420004 93318.23444219989 94705.62622139389 137403.0394595341 0.9960882264917037 0.8188535119735431 0.8167062342591069 0.9599177151233567 0.9193603264969389 0.8701015053240188 0.7455508929580078 0.6791569881515073 0.6892542304297801 1.0 17.068054392455245 -7.199398807536968 4.355791339881219 0.7513634117289001 0.8955061560606075 0.2410472011264645 0.09900473565345679 0.26788987853236434 10.32112154077435 0.03852488961688631 0.028865282336244 6.318313815390155e-08 7.199398807536968 0.14414274433170737 SFSKEELMSS(ph)DLEETAGSTSIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SFSKEELMSSDLEETAGSTSIPK 23 1 O00567 O00567 NOP56 Nucleolar protein 56 1 S(0.012)FS(0.039)KEELMS(0.41)S(0.536)DLEET(0.001)AGS(0.001)TSIPK;S(0.002)FS(0.009)KEELMS(0.071)S(0.756)DLEET(0.146)AGS(0.01)T(0.004)S(0.002)IPK;S(0.002)FS(0.002)KEELMS(0.258)S(0.73)DLEET(0.004)AGS(0.003)T(0.001)SIPK 59.538999999999994 0.0089968 11315900.0 40289.0 33121.0 32845.0 52030.0 51869.0 56016.0 52666.0 54890.0 50218.0 42550.0 True False 47109.13195597806 36409.03399093664 33628.14936535614 49114.927783535924 41705.64179473197 53078.422349467815 47677.09521117949 53449.195660762365 50952.34324687785 50263.9781743853 0.9372344503361463 0.7243563942475768 0.6690307967405008 0.9771396846691507 0.8297322120035718 1.0559932635120546 0.9485340584417948 1.0633697849248283 1.0136949978392944 1.0 15.617237238299484 -6.3924084875298135 1.26707454101475 1.0185432555193288 0.7853948507460712 0.5031404050468504 0.09135719732326235 0.3506369080503424 1.1580380636681384 0.037673524634397985 0.047797922789756295 4.051273026438396e-07 6.3924084875298135 -0.2331484047732576 SFSKEELMSS(ph)DLEETAGSTSIPK ddPTM_PC-9_Lapatinib_30min_R1 3 SFSKEELMSSDLEETAGSTSIPK 23 1 O00567 O00567 NOP56 Nucleolar protein 56 1 SFSKEELMS(0.145)S(0.851)DLEET(0.002)AGST(0.001)SIPK;S(0.001)FS(0.001)KEELMS(0.267)S(0.71)DLEET(0.016)AGS(0.002)T(0.002)S(0.001)IPK;SFSKEELMS(0.411)S(0.587)DLEET(0.001)AGSTSIPK 78.354 0.00012638 24690100.0 228388.0 172878.0 205236.0 169041.0 169316.0 183586.0 158614.0 166158.0 206955.0 125027.0 True False 225131.14523877052 172477.71161259295 188362.28831387064 181472.8390442456 159357.1657680638 175734.4547398684 166826.25681573758 173878.30726960103 183645.54856723573 146637.75036199472 1.535287773325794 1.1762162961911844 1.2845415852935098 1.2375588045796928 1.0867403883015767 1.198425741707334 1.1376760513844821 1.185767695155984 1.2523756543856024 1.0 17.161897032540658 -2.26718766031215 1.218912373619358 1.1711358612944958 199.9999999999677 0.6380625064899318 0.08078358455930681 527.411572118864 1.8589037354864517 0.022802053370493448 291973.9052453996 0.0054052071140345435 2.26718766031215 198.82886413867323 SFSKEELMSSDLEET(ph)AGSTSIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFSKEELMSSDLEETAGSTSIPK 23 1 O00567 O00567 NOP56 Nucleolar protein 56 1 S(0.027)FS(0.057)KEELMS(0.121)S(0.121)DLEET(0.553)AGS(0.078)T(0.031)S(0.013)IPK 43.681000000000004 0.045656 2683000.0 9901.1 9753.6 9270.4 12088.0 11783.0 11356.0 10847.0 12598.0 10251.0 7328.1 True False 11577.160674361096 10721.872948703227 9491.441494187786 11410.748549824757 9474.205734973239 10760.471368904527 9819.49363452064 12267.315848684359 10400.901482013327 8656.626520792319 1.3373755523071207 1.2385740476328049 1.0964365242499867 1.3181518831172077 1.0944454762160731 1.2430328769595167 1.1343325960679065 1.417101202092933 1.201495924195348 1.0 13.07958920223374 -4.824825377233409 4.0820673337179185 1.202420210637307 1.3431336180052926 0.12747540784397915 0.11395556381874514 0.4558926817083609 13.327814070102983 0.027123606710141135 0.16750963197113394 1.4968373891471284e-05 4.824825377233409 0.14071340736798565 SFSLASSSNS(ph)PISQR ddPTM_PC-9_AZD4547_30min_R2 4 SFSLASSSNSPISQR 15 0 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 SFSLASSSNS(0.97)PIS(0.03)QR;SFSLAS(0.006)S(0.018)S(0.018)NS(0.954)PIS(0.005)QR;SFSLAS(0.001)S(0.009)S(0.002)NS(0.988)PISQR;SFSLASSSNS(1)PISQR 265.6 1.4420999999999996e-61 213363000.0 219854.0 217572.0 358547.0 570441.0 469692.0 401929.0 348915.0 499992.0 333657.0 425383.0 True False 289762.99875271646 287897.8941476462 353792.43250955205 438934.6406755948 404483.3732740728 376796.31609186775 379967.75906208047 422729.7250731534 351293.42784573446 410490.4706465086 0.7058945809298558 0.7013509806798115 0.8618773340885135 1.0692931311761942 0.9853660491485348 0.917917328259597 0.9256433126538701 1.029816171876946 0.855789483474389 1.0 18.646989205305665 -5.423167998970459 3.484970898479657 0.9673562262654244 0.70410882127427 0.7671509216052752 0.057914227001494074 0.10767944048448544 2.405357747009935 0.015593611790541832 0.03542831448224992 3.7742616219407627e-06 5.423167998970459 -0.2632474049911544 SFSLASSSNS(ph)PISQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SFSLASSSNSPISQR 15 0 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 SFS(0.006)LAS(0.009)S(0.006)S(0.006)NS(0.972)PISQR;SFS(0.003)LAS(0.012)S(0.026)S(0.005)NS(0.955)PISQR;SFSLASS(0.011)S(0.011)NS(0.856)PIS(0.123)QR;SFSLASS(0.005)S(0.001)NS(0.994)PISQR 223.68 3.323e-24 184777000.0 113198.0 109474.0 174323.0 175670.0 222386.0 191001.0 216664.0 143024.0 166949.0 135669.0 True False 132360.1856375887 120341.85523153884 178479.52144365868 165827.77942982456 178811.05971125892 180984.57132195632 196140.01740848014 139269.77154645458 169390.31328852198 160264.7157447871 0.8258847558708128 0.7508942606130269 1.1136544972748568 1.0347117184165249 1.1157231888521606 1.1292851984348475 1.2238502810613818 0.8689983375269835 1.0569407776460722 1.0 17.29009730776942 -5.260867798567461 24.999854421743308 1.071502172550426 0.7883894869490098 0.6072452361782534 0.08987706989277136 32.14459708624354 1405860.88813971 0.02383213888884314 0.05588888662535284 5.484438886015045e-06 5.260867798567461 -0.2831126856014161 SFSLASSSNS(ph)PISQR ddPTM_PC-9_Lapatinib_30min_R1 4 SFSLASSSNSPISQR 15 0 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 SFSLASS(0.001)SNS(0.976)PIS(0.023)QR;SFSLASS(0.059)S(0.012)NS(0.926)PIS(0.002)QR;SFSLASSSNS(0.978)PIS(0.022)QR;SFSLAS(0.002)S(0.009)S(0.002)NS(0.988)PISQR 311.7 4.0519999999999996e-122 202027000.0 483215.0 447225.0 504043.0 433818.0 398785.0 431996.0 325262.0 328475.0 488116.0 233418.0 True False 476324.2654892225 446189.4779899218 462602.5302022468 465722.4228944239 375329.250341476 413520.538111861 342102.47484081105 343737.14765694266 433139.23599065014 273763.99029006535 1.739908396953651 1.6298326069734879 1.689785898109165 1.7011821839715657 1.3709956884533925 1.5105001124279247 1.2496255423452076 1.2555966447330695 1.5821629262918016 1.0 18.06257316775833 -1.5228793650028707 0.05978454510493331 0.30634840465590757 3.907777205909271 0.7029352320068474 0.12659835735143252 187.9883565540622 0.8430964658310798 10.339937444833959 59.06705472207259 0.029999957191114545 1.5228793650028707 3.601428801253363 SFSLEGLT(ph)GGAGVGNKPSSSLEVSSANAEELR ddPTM_PC-9_AZD4547_30min_R2 1 SFSLEGLTGGAGVGNKPSSSLEVSSANAEELR 32 1 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36;H0YMW2;H0YLH1 Q12802-2 AKAP13 A-kinase anchor protein 13 1 S(0.108)FS(0.367)LEGLT(0.523)GGAGVGNKPS(0.003)SSLEVSSANAEELR 89.87899999999999 1.1636e-09 11402000.0 18392.0 19336.0 23274.0 22489.0 21387.0 27291.0 21051.0 26145.0 29470.0 21947.0 True False 24240.273422634844 25585.983863911177 22965.371553038556 17304.508501586424 18417.784216492102 25584.48945575746 22924.49821880937 22104.891002331264 31027.724035802585 21178.642210146892 1.1445622047961646 1.20810312625484 1.0843646785833903 0.8170735559853628 0.8696395186121971 1.2080325642169678 1.0824347468236666 1.0437350413210436 1.4650478405521625 1.0 14.370322478819295 SFSLSS(ph)NFTTPEEVPTGTK ddPTM_PC-9_AZD4547_30min_R2 3 SFSLSSNFTTPEEVPTGTK 19 0 P17029;E9PC66;B3KRF7 P17029 ZKSCAN1 Zinc finger protein with KRAB and SCAN domains 1 1 S(0.002)FS(0.059)LS(0.036)S(0.865)NFT(0.032)T(0.006)PEEVPTGTK;S(0.003)FS(0.146)LS(0.03)S(0.795)NFT(0.01)T(0.016)PEEVPTGTK;SFS(0.003)LS(0.02)S(0.975)NFT(0.002)TPEEVPTGTK 261.06 3.537999999999999e-157 8414700.0 40825.0 50708.0 68391.0 95868.0 66173.0 71541.0 67995.0 100900.0 83265.0 76384.0 True False 53806.500787248166 67098.36935101409 67484.09065411451 73767.11374583513 56986.02117912431 67067.52996058574 74046.42327623101 85308.22345133792 87666.21791113343 73709.81940948014 0.7299773791106029 0.9103043514224683 0.9155373218216715 1.0007772958448955 0.7731130212455125 0.9098859622488763 1.0045666082137705 1.1573522243681695 1.1893424595727375 1.0 16.169569203343542 -7.466696896840352 2.5865716425846164 1.1288756495397057 0.8772306348742269 0.6187859344719928 0.08545970455824667 0.18764426995355957 2.477233793391772 0.04436518613448278 0.02540021537503937 3.414311203733317e-08 7.466696896840352 -0.25164501466547873 SFSLSS(ph)NFTTPEEVPTGTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFSLSSNFTTPEEVPTGTK 19 0 P17029;E9PC66;B3KRF7 P17029 ZKSCAN1 Zinc finger protein with KRAB and SCAN domains 1 1 S(0.003)FS(0.177)LS(0.047)S(0.771)NFT(0.002)TPEEVPTGTK 263.19 3.0243999999999994e-78 4211900.0 21382.0 15511.0 15082.0 15816.0 22406.0 19501.0 22715.0 25481.0 20436.0 17318.0 True False 25001.550286249905 17050.829571372178 15441.612078803508 14929.880796163832 18015.705142816798 18478.333230451513 20563.270757641392 24812.15074935117 20734.837838886375 20457.616310787434 1.2221145370228899 0.8334709827547779 0.7548099370042953 0.729795718589717 0.8806355964999206 0.9032495746196867 1.0051645531546236 1.2128563940397867 1.0135510180603378 1.0 14.320350433872772 -7.34008175916505 2.9289649167227547 1.0876094444785933 0.868815376171109 0.270756551355532 0.1375844862541003 0.3297753941931923 5.527054658505917 0.06612894297426372 0.04239377338749268 4.570021474641767e-08 7.34008175916505 -0.21879406830748427 SFSLSSNFT(ph)TPEEVPTGTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFSLSSNFTTPEEVPTGTK 19 0 P17029;E9PC66;B3KRF7 P17029 ZKSCAN1 Zinc finger protein with KRAB and SCAN domains 1 1 SFSLSSNFT(0.498)T(0.498)PEEVPT(0.003)GTK 111.72 0.00096166 0.0 4982.6 4507.5 4407.3 6827.0 5560.8 7971.2 6619.3 6432.8 7319.3 6011.4 True False 5826.0557691641925 4954.974810970287 4512.386746778329 6444.50532343263 4471.201158536806 7553.176239504389 5992.271984418038 6263.945816114994 7426.330915744811 7101.219233783783 0.8204303482769482 0.6977639540259764 0.6354383097075527 0.9075209638329624 0.6296385185892072 1.0636449869862399 0.8438370633468165 0.882094413634564 1.045782515826905 1.0 12.79385103202897 -6.761166775508247 24.999999948129126 0.9520005246735602 0.7396166405725155 0.5659994215479676 0.09978600848290618 5.871545269277422 538484.737887359 0.0331534014237773 0.031206399457798267 1.7331383191835382e-07 6.761166775508247 -0.2123838841010447 SFSPKS(ph)PLELGEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFSPKSPLELGEK 13 1 Q15742-2;Q15742-3;Q15742 Q15742-2 NAB2 NGFI-A-binding protein 2 1 S(0.136)FS(0.136)PKS(0.729)PLELGEK 52.52 0.043497 2745100.0 17598.0 11640.0 13587.0 29990.0 21793.0 27316.0 26487.0 30033.0 29341.0 23937.0 True False 20576.993823656612 12795.542273919944 13910.96560898444 28309.757528891838 17522.818092359495 25883.500872930283 23977.959610726295 29244.665572593833 29770.056617281523 28276.58861481226 0.7277042540017599 0.4525136482417541 0.4919605330926444 1.0011730168207844 0.6196934973683649 0.9153685837255349 0.8479792218699892 1.0342359883283254 1.0528164137058222 1.0 14.787320458488852 -6.543882467303254 0.5745759687668328 1.0440229131143406 0.5338236316433299 0.5675932872054847 0.14197859681319133 0.6762199600127625 0.48366934470282547 0.11283188518926701 0.1656564534902787 2.8583639950019734e-07 6.543882467303254 -0.5101992814710107 SFSS(ph)PENFQR ddPTM_PC-9_AZD4547_30min_R2 2 SFSSPENFQR 10 0 G3V1T9;J3KPD3;Q9Y580;I3L521;F5GXV8;F5GY08 G3V1T9 RBM7 RNA-binding protein 7 1 S(0.001)FS(0.077)S(0.922)PENFQR;SFS(0.049)S(0.951)PENFQR 158.08 0.00041098 14214100.0 83140.0 83241.0 111512.0 129910.0 135091.0 117725.0 87019.0 133309.0 104661.0 117171.0 True False 109576.79058057116 110147.02538352451 110033.27801935363 99961.25658949216 116335.9464903977 110363.63713968154 94763.52242185977 112709.15718606906 110193.16679033384 113068.8789540765 0.9691153887275767 0.9741586403121701 0.9731526396758936 0.884074004395957 1.0288944895053584 0.9760743907658825 0.8381043776010945 0.9968185607628289 0.97456672260003 1.0 16.7868423714309 SFSS(ph)PENFQR ddPTM_PC-9_Lapatinib_30min_R1 3 SFSSPENFQR 10 0 G3V1T9;J3KPD3;Q9Y580;I3L521;F5GXV8;F5GY08 G3V1T9 RBM7 RNA-binding protein 7 1 S(0.024)FS(0.141)S(0.834)PENFQR;SFS(0.364)S(0.636)PENFQR;SFS(0.019)S(0.981)PENFQR 142.19 0.00011124 18688400.0 107802.0 107740.0 109604.0 83174.0 107418.0 115205.0 104929.0 90495.0 113976.0 97555.0 True False 106264.72371153462 107490.53464952584 100592.78220367487 89290.89342033047 101099.88443191341 110277.95070597179 110361.71019845986 94699.7280682395 101138.82265951192 114417.25176613356 0.9287473879265818 0.9394609028823225 0.879174955270595 0.7803971170609758 0.8836069986942129 0.9638227540316874 0.9645548070323945 0.8276700113528661 0.8839473164959208 1.0 16.80394507166654 -6.559336062185063 24.936615864563233 0.9199799903196484 0.8791237814265043 0.11931891104108261 0.059984845909142194 457.81787801412645 313142.1330481485 0.02138650532915627 0.021386579887342234 2.7584425148447974e-07 6.559336062185063 -0.04085620889314412 SFSSPPS(ph)PSNKR ddPTM_PC-9_Lapatinib_30min_R1 1 SFSSPPSPSNKR 12 1 Q5T0Z8 Q5T0Z8 C6orf132 Uncharacterized protein C6orf132 1 SFS(0.002)S(0.026)PPS(0.971)PS(0.001)NKR 115.37 0.00066363 0.0 43774.0 31092.0 34823.0 30302.0 34809.0 34127.0 31049.0 29792.0 34414.0 29801.0 True False 43149.774732831545 31020.00838428677 31959.987360667263 32530.510164508727 32761.603057127093 32667.46776392257 32656.56529607623 31176.24508104313 30537.9329245143 34952.06314266355 1.2345415650202811 0.887501497627555 0.9143948736363986 0.9307178815662243 0.9373295912005059 0.934636322628053 0.9343243963248233 0.8919715255088463 0.8737090225509112 1.0 15.09308999674787 -4.757770663326164 24.999970681711435 0.9205352987500558 1.2345420098134918 0.8862365716760876 0.03350655824147802 31.316386759579242 213369.74460475336 0.008078529648569883 0.058533204507498104 1.7467443078062078e-05 4.757770663326164 0.31400671106343603 SFSTGSDLGHWVT(ph)TPPDIPGSR ddPTM_PC-9_AZD4547_30min_R2 2 SFSTGSDLGHWVTTPPDIPGSR 22 0 Q96AG3-3;Q96AG3 Q96AG3-3 SLC25A46 Solute carrier family 25 member 46 1 SFSTGSDLGHWVT(0.602)T(0.398)PPDIPGSR;SFSTGSDLGHWVT(0.532)T(0.468)PPDIPGSR 114.15 3.6645999999999996e-06 6330300.0 17151.300000000003 10196.2 41022.0 81132.0 70021.0 52200.0 43582.0 77489.0 42219.0 53481.0 True False 22605.05663079803 13491.922252441633 40478.02147670134 62428.27087690469 60299.79280043928 48935.92574806855 47460.713570478845 65514.85557007646 44450.61014820323 51608.646468349514 0.438009096879943 0.26142755479386465 0.7843263531727314 1.2096475135264517 1.168404849319578 0.9482117648266538 0.9196271713807781 1.2694550245617338 0.861301607192195 1.0 15.655325173337337 -5.4528399524518525 3.6710656550000977 1.058494306712862 0.3561856247530355 0.8164816442651159 0.13212696697612036 0.0879052005708488 2.2752912324907375 0.03548657661963963 0.07785849331528885 3.5250075177827277e-06 5.4528399524518525 -0.7023086819598265 down SFSTGSDLGHWVT(ph)TPPDIPGSR ddPTM_PC-9_Lapatinib_30min_R1 2 SFSTGSDLGHWVTTPPDIPGSR 22 0 Q96AG3-3;Q96AG3 Q96AG3-3 SLC25A46 Solute carrier family 25 member 46 1 SFSTGSDLGHWVT(0.563)T(0.434)PPDIPGS(0.003)R;SFSTGSDLGHWVT(0.792)T(0.207)PPDIPGS(0.001)R 86.08 0.00047185 4677400.0 44489.0 23486.4 31612.0 15506.0 27001.4 40387.0 23024.6 22914.8 69955.0 15015.3 True False 43854.578701716615 23432.018683800106 29012.983385848835 16646.362966499648 25413.230738794904 38659.7421566953 24216.701127766963 23979.505262590184 62075.93124119243 17610.674598370395 2.4902270754451794 1.330557699701543 1.6474657585538235 0.945242777243753 1.443058333560176 2.1952448181782134 1.375114905025152 1.3616460362517362 3.5249036539995258 1.0 14.104162553970289 SFSTGSDLGHWVTT(ph)PPDIPGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFSTGSDLGHWVTTPPDIPGSR 22 0 Q96AG3-3;Q96AG3 Q96AG3-3 SLC25A46 Solute carrier family 25 member 46 1 SFSTGSDLGHWVT(0.214)T(0.773)PPDIPGS(0.013)R 66.613 0.0056472 2187300.0 2352.3 4760.4 9774.0 9935.6 20391.0 21473.0 16423.0 13930.0 20805.0 12646.0 True False 2750.4979299572387 5232.98105161241 10007.049228101416 9378.940543649805 16395.52992801828 20346.918078943905 14867.29454777656 13564.352260055013 21109.23376580695 14938.619694319075 0.18411995125648792 0.3502988334057685 0.6698777686874873 0.6278318034440941 1.097526429048411 1.3620346789256252 0.9952254526855893 0.9080057286158323 1.413064539947721 1.0 13.866759231012793 -5.7083919810368915 1.0360986406525199 1.139286719112727 0.18881250210542355 0.7991625777709329 0.17130661872247996 0.28514632174292753 0.5683196565340991 0.06703238050363071 0.21435364919421615 1.9570774773006296e-06 5.7083919810368915 -0.9504742170073034 down SFT(ph)FGAYGGVDK ddPTM_PC-9_AZD4547_30min_R2 1 SFTFGAYGGVDK 12 0 P47736-4 P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 S(0.151)FT(0.849)FGAYGGVDK 171.73 0.0027364 14005000.0 37224.0 29796.0 39248.0 51627.0 50187.0 41285.0 37511.0 38206.0 36886.0 41874.0 True False 49060.45769270112 39426.97430746264 38727.54587581234 39725.19277919879 43219.40134067841 38703.442423544286 40849.40633156421 32302.14058653925 38835.71865573852 40408.00400545363 1.2141272230640179 0.9757218966356619 0.9584127409655155 0.9831020798215452 1.0695752587741116 0.9578162390382042 1.0109236359719973 0.7993995591115963 0.961089754655961 1.0 15.30235346943872 -7.569377659348606 24.90565503110562 0.9091787834451873 1.0179925057648915 0.22974942818773247 0.08619710309112916 167.28931427815758 89601.2478412738 0.03944126732948416 0.022771437020730426 2.6953945174034364e-08 7.569377659348606 0.10881372231970421 SFT(ph)FGAYGGVDK ddPTM_PC-9_Lapatinib_30min_R1 3 SFTFGAYGGVDK 12 0 P47736-4 P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 S(0.034)FT(0.966)FGAYGGVDK;S(0.005)FT(0.995)FGAYGGVDK;S(0.33)FT(0.67)FGAYGGVDK 145.81 0.000281 9043000.0 37007.6 28066.800000000003 37506.9 35150.5 39518.0 53374.1 50033.5 37712.3 60808.1 41863.700000000004 True False 36479.86483763734 28001.81304901906 34423.22746282089 37735.5850286306 37193.6289353773 51091.41416410403 52623.98981420427 39464.551133519795 53959.25144031955 49099.78476512611 0.7429740275266488 0.5703041914128264 0.7010871356664383 0.768548888944069 0.7575110382519367 1.04056289469506 1.0717763848851183 0.8037622022642777 1.0989712418993118 1.0 15.583429079874229 -6.652954936644498 4.003803432175504 0.9950058283630429 0.6944914882327949 0.7328534639262274 0.0893534161199002 0.12270199433178944 3.6281191606494088 0.03109508371222007 0.03079298378656491 2.2235405981697017e-07 6.652954936644498 -0.3005143401302479 SFT(ph)PDHVVYAR ddPTM_PC-9_AZD4547_30min_R2 2 SFTPDHVVYAR 11 0 Q6NZI2;Q6NZI2-3;Q6NZI2-2 Q6NZI2 PTRF Polymerase I and transcript release factor 1 S(0.235)FT(0.765)PDHVVYAR;S(0.226)FT(0.774)PDHVVYAR 138.2 0.00020762 49217000.0 146181.0 117471.0 187041.0 247971.0 181568.0 192423.0 130077.0 201321.0 150063.0 176798.0 True False 192663.51724631278 155441.20347939132 184560.7141295817 190805.11706375927 156360.41729181446 180390.75939119916 141653.60100746134 170211.4653463509 157995.02382031354 170608.35583312268 1.1292736296853065 0.9110995925160499 1.081780040774241 1.1183808444317445 0.9164874517913731 1.0573383613616496 0.8302852478457569 0.9976736749801398 0.9260684979278118 1.0 17.38032878125596 -6.272651901543976 24.951485666833577 0.9534428488668516 1.0510344274069945 0.2937870439597354 0.07961471759084057 978.4679122219419 2177402.211243659 0.023918979726904134 0.027359957119094863 5.337625488062531e-07 6.272651901543976 0.09759157854014289 SFT(ph)PDHVVYAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SFTPDHVVYAR 11 0 Q6NZI2;Q6NZI2-3;Q6NZI2-2 Q6NZI2 PTRF Polymerase I and transcript release factor 1 S(0.036)FT(0.964)PDHVVYAR;S(0.234)FT(0.766)PDHVVYAR;S(0.09)FT(0.91)PDHVVYAR 160.56 0.0025497 14695200.0 92755.0 88815.0 97687.0 83628.0 106133.0 73653.0 78029.0 75075.0 71459.0 59339.0 True False 108456.58950524312 97631.96624211324 100016.22856001035 78942.59428563403 85337.00053211521 69790.5070213038 70637.52823896108 73104.36079853779 72503.9526878538 70096.69097273445 1.5472426444128375 1.3928184752699555 1.4268323821293323 1.126195733210008 1.2174183880564176 0.995631977099322 1.0077155891201341 1.042907443761835 1.034342016459175 1.0 16.097058720648334 -5.7413696997368255 0.7995754806528232 1.0110984812169814 1.5651864186371212 0.9026565679346419 0.060936250832716574 0.24799138535008672 0.27772657945331475 0.027034417702230914 0.09704101070463768 1.8139708352678126e-06 5.7413696997368255 0.5540879374201397 SFT(ph)PDHVVYAR ddPTM_PC-9_Lapatinib_30min_R1 2 SFTPDHVVYAR 11 0 Q6NZI2;Q6NZI2-3;Q6NZI2-2 Q6NZI2 PTRF Polymerase I and transcript release factor 1 S(0.296)FT(0.704)PDHVVYAR;S(0.108)FT(0.892)PDHVVYAR 119.69 0.0019718 38130000.0 211390.0 200781.0 248046.0 220215.0 250360.0 189347.0 180287.0 186211.0 233100.0 169864.0 True False 208375.53983582213 200316.103930448 227652.61536524905 236410.3457157051 235634.31702669797 181249.0701994153 189621.37870893386 194863.04285667656 206845.82334818033 199224.76607044777 1.0459319086972276 1.005477922657539 1.1426923462153742 1.186651390681559 1.1827561486174638 0.9097717807600482 0.9517962171524494 0.9781065210927197 1.0382535636911612 1.0 17.604037477596293 -6.763249890698668 24.999999241393155 0.9727304352838799 1.1125194901701556 0.5613341195624727 0.060579548706333954 41.22569833760568 569247.8069798304 0.023446621695938856 0.021742536654473513 1.7248451398302716e-07 6.763249890698668 0.1397890548862757 SFTPDHVVY(ph)AR ddPTM_PC-9_AZD4547_30min_R2 1 SFTPDHVVYAR 11 0 Q6NZI2;Q6NZI2-3;Q6NZI2-2 Q6NZI2 PTRF Polymerase I and transcript release factor 1 SFTPDHVVY(1)AR 110.54 0.0033465000000000005 4009600.0 12122.0 18145.0 24677.0 43579.0 35602.0 32450.0 30337.0 36043.0 31800.0 29774.0 True False 15976.543846736598 24010.01640518559 24349.766856334634 33532.5348388383 30659.27683525283 30420.896370207363 33036.93422944372 30473.38253574398 33480.88307901331 28731.621322500276 0.5560613397833232 0.8356652113601014 0.847490177564949 1.167095113166424 1.0670917763782084 1.0587949781443133 1.1498458043358617 1.0606217516823422 1.1652973810006955 1.0 14.810351785852978 -4.871590488299275 0.9669906821119545 1.1013993615942927 0.3409609509201662 0.8469875066771689 0.07168421706653715 0.607167698155265 0.4979791630580426 0.023196250084857886 0.46972641144597166 1.3440316990704739e-05 4.871590488299275 -0.7604384106741265 SFTPDHVVY(ph)AR ddPTM_PC-9_Lapatinib_30min_R1 2 SFTPDHVVYAR 11 0 Q6NZI2;Q6NZI2-3;Q6NZI2-2 Q6NZI2 PTRF Polymerase I and transcript release factor 1 SFTPDHVVY(1)AR;SFTPDHVVY(1)AR 82.171 0.024775 5285900.0 65588.0 62427.0 72823.0 56577.0 70387.0 60100.0 61948.0 52316.0 80565.0 57618.0 True False 64652.703092633805 62282.45411700344 66835.77404490908 60737.86131533923 66246.9750461663 57529.663099942714 65155.36432610808 54746.79234894775 71490.92131293929 67577.19452884099 0.9567236927102818 0.9216490052782847 0.9890285400407458 0.8987922884164297 0.9803155562768003 0.8513177189590175 0.9641620191601871 0.8101370992189175 1.0579149047453869 1.0 16.04424883772589 -8.300587296560007 24.997899509951242 1.0289575133237538 0.9240547141937896 0.37534833601262085 0.0553639731401852 624.4307452965681 398724.9414267085 0.04941551626441203 0.012759747086458086 5.005099360368418e-09 8.300587296560007 -0.10490279912996425 SFTSSSPSS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 1 SFTSSSPSSPSR 12 0 H7BZX1;H7C1R7;H7BZK1;H7BXR3;O94875-9;O94875-5;O94875-3;O94875-8;O94875-2;O94875-4;O94875-12;O94875-10;O94875-7;O94875;O94875-11 H7BZX1 SORBS2 Sorbin and SH3 domain-containing protein 2 1 SFTS(0.01)S(0.01)S(0.01)PS(0.422)S(0.502)PS(0.047)R 67.252 0.037328 4905800.0 18777.0 22656.0 30774.0 38439.0 38801.0 29373.0 24563.0 37136.0 26637.0 32206.0 True False 24747.695414137383 29979.108937772635 30365.916652625587 29577.48242662993 33414.15090401227 27536.301666628715 26749.05941516387 31397.48450038531 28044.977439486713 31078.477742743467 0.7962968977756878 0.964626040758141 0.977072201025539 0.9517030618893808 1.0751540400595765 0.8860247884263953 0.860694002987631 1.010264555435516 0.9023922494413341 1.0 14.923628220271294 -4.759918133099625 24.712571335029512 0.9576470559264385 0.7962966666918189 0.39441049637736325 0.06034432694641993 35.98338975169309 584321.1244767434 0.01509802788775113 0.09260336299827124 1.7381284446488968e-05 4.759918133099625 -0.16135038923461964 SFTSSSPSS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SFTSSSPSSPSR 12 0 H7BZX1;H7C1R7;H7BZK1;H7BXR3;O94875-9;O94875-5;O94875-3;O94875-8;O94875-2;O94875-4;O94875-12;O94875-10;O94875-7;O94875;O94875-11 H7BZX1 SORBS2 Sorbin and SH3 domain-containing protein 2 1 SFTS(0.002)S(0.002)S(0.002)PS(0.034)S(0.959)PS(0.002)R 90.79299999999999 0.023829 0.0 21910.0 19503.0 26849.0 28962.0 33942.0 32765.0 29473.0 27594.0 29218.0 24894.0 True False 25618.930257774555 21439.128949163285 27489.181985399522 27339.353036070872 27291.30875468572 31046.745720514005 26681.104073958384 26869.686738259727 29645.257974974666 29407.085139204435 0.8711822384470315 0.7290463793904358 0.9347809160708677 0.9296859211531666 0.928052155645374 1.055757331049572 0.9073018950248872 0.913714725926306 1.0080991650360038 1.0 14.843876169431605 -5.386116198962509 5.725765629070566 0.9576651361611191 0.801309505582674 0.5753353223697433 0.05506970915170727 0.14908270292155 6.266217655338088 0.014127588435937628 0.029993743591828773 4.110397294231306e-06 5.386116198962509 -0.15635563057844515 SFTSSSPSS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 1 SFTSSSPSSPSR 12 0 H7BZX1;H7C1R7;H7BZK1;H7BXR3;O94875-9;O94875-5;O94875-3;O94875-8;O94875-2;O94875-4;O94875-12;O94875-10;O94875-7;O94875;O94875-11 H7BZX1 SORBS2 Sorbin and SH3 domain-containing protein 2 1 SFTS(0.001)S(0.001)S(0.001)PS(0.069)S(0.922)PS(0.007)R 94.402 0.00492 3629100.0 28981.0 24623.0 28405.0 22379.0 26079.0 25762.0 30558.0 25135.0 29617.0 20919.0 True False 28567.7256255355 24565.986956332596 26069.650546470853 24024.82631415553 24545.084493286726 24660.21931415515 32140.143718557672 26302.86385982875 26281.221579163695 24534.821277184616 1.164374718804296 1.0012702631413484 1.0625571815643713 0.9792134225365913 1.0004183122422683 1.0051110230457292 1.309980755736965 1.0720625825095482 1.0711804778298137 1.0 14.582543141745948 SFVEY(ph)NS(ph)WHVLS(ph)S(ph)VNICCSKLVK ddPTM_PC-9_AZD4547_30min_R2 1 SFVEYNSWHVLSSVNICCSKLVK 23 1 Q13202 Q13202 DUSP8 Dual specificity protein phosphatase 8 4 S(0.126)FVEY(0.894)NS(0.982)WHVLS(0.984)S(0.985)VNICCS(0.031)KLVK 46.027 0.046339 0.0 704.11 2197.1 2557.9 2383.0 2545.4 2219.4 1258.1 749.4 2122.5 2123.6 True False 928.0023336021874 2907.2696083677724 2523.9805746978304 1833.6361669829882 2192.015146802216 2080.620567150641 1370.0684627373557 633.5974494988358 2234.6910168303684 2049.253410373533 0.4528489882727746 1.4186969721025582 1.2316585942573912 0.8947825377285855 1.0696652428177054 1.0153066266076827 0.6685695657754807 0.30918452851731265 1.0904903246802622 1.0 11.000882683498133 -7.238833485166298 8.138954537392767 0.7094084546354437 1.0396682389909786 0.12070112003349331 0.3064058368120574 0.38406513905392087 121.98904672947953 0.1157345686189187 0.08760445833557626 5.769876464597165e-08 7.238833485166298 0.33025978435553494 SFVT(ph)PPQSHFVR ddPTM_PC-9_AZD4547_30min_R2 1 SFVTPPQSHFVR 12 0 H0YNU5;A0A3B3IT82;P54132;H0YLV8 H0YNU5 BLM Bloom syndrome protein 1 S(0.051)FVT(0.948)PPQSHFVR 78.505 0.034393 2733500.0 12437.0 9816.0 17236.0 22403.0 19459.0 15762.0 15525.0 19359.0 13144.0 19754.0 True False 16391.707294329575 12988.830037657857 17007.439378197672 17238.334472899656 16757.45373678964 14776.399648296112 16906.694924089843 16367.511375564402 13838.765005992162 19062.418472649646 0.8598965193135409 0.6813841620513135 0.8921973569408093 0.9043099383025744 0.8790832999932763 0.7751587066193608 0.8869123793681903 0.8586272197857874 0.7259711051799502 1.0 14.218443546916633 -12.132968100127274 2.208576248545889 4.752383272823723 0.8314204475583694 0.3319521497086153 0.07259803807011528 3809666.4611166823 524765.049891442 70245879.58106881 0.0191802961349803 7.362611754907021e-13 12.132968100127274 -3.9209628252653532 SFYPEEVSSMVLTK ddPTM_PC-9_Lapatinib_30min_R1 3 SFYPEEVSSMVLTK 14 0 P11142;E9PKE3;P11142-2;E9PN89;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65;E9PPY6;E9PN25 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 ;; 184.98 2.8448000000000003e-05 29234400.0 76882.0 61146.0 82869.0 78052.0 78098.0 75649.0 83037.0 63492.0 77159.0 70046.0 False True 75785.64858156789 61004.42019379908 76055.83070359073 83792.20445383927 73504.42918657558 72413.66861643216 87336.24955683855 66442.07010894167 68468.54089970942 82153.35776957193 0.9224899704542263 0.7425675815333987 0.9257787237000846 1.0199486269187445 0.8947221535697261 0.8814450265020431 1.0630880091572625 0.8087565975733079 0.8334235235004465 1.0 16.326031921718247 -5.3850190160770275 14.297857963979578 0.9268373343364236 0.8325431661317385 0.1646071990011555 0.08633300181497962 1.5601551665076137 172.99601916021334 0.022534932316300615 0.0469133153213505 4.120794753345598e-06 5.3850190160770275 -0.09429416820468506 SGAAQPGAGGAQPGAAQPSR ddPTM_PC-9_AZD4547_30min_R2 1 SGAAQPGAGGAQPGAAQPSR 20 0 Q5T8A7 Q5T8A7 PPP1R26 Protein phosphatase 1 regulatory subunit 26 0 71.929 0.0029564 7854600.0 13644.0 12504.0 25576.0 34272.0 35902.0 26631.0 20219.0 29094.0 22544.0 29314.0 False True 17982.508187169962 16545.673470952905 25236.845528938476 26371.11989712171 30917.62701362976 24965.759360092226 22018.451830606937 24598.19081360971 23735.629815511813 28287.72578248718 0.6357000320719618 0.58490645724501 0.8921482668133932 0.9322460242967981 1.092969694749047 0.8825650938524167 0.7783747622524846 0.869571170293172 0.8390787579751797 1.0 14.78788857416224 -5.273604721328283 10.072595394374337 0.9078124529288902 0.6102002891683901 0.6783869123082927 0.08275940757457732 0.1793720867559051 145.19648547315268 0.023499931460956656 0.05164988987465375 5.325927848628853e-06 5.273604721328283 -0.29761216376050015 SGAASMPSS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 SGAASMPSSPK 11 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 SGAASMPS(0.062)S(0.938)PK;SGAAS(0.001)MPS(0.224)S(0.776)PK;SGAAS(0.003)MPS(0.23)S(0.768)PK 91.09299999999999 0.00838 59953000.0 139151.0 122861.0 106392.0 128472.0 136404.0 118848.0 123448.0 106796.0 119754.0 107876.0 True False 183398.12347939692 162573.41557219668 104981.1725647022 98854.76527261376 117466.65910442735 111416.41577215449 134434.6328495358 90293.13212793901 126083.95195736359 104099.29407489872 1.7617614519791387 1.5617148705660409 1.008471512680662 0.9496199388392437 1.1284097567454292 1.0702898301307515 1.2914077280179346 0.8673750665684028 1.2111893080336076 1.0 16.66760075980713 -5.146318463273174 3.6645778083892173 1.0671479809702968 1.7239789160024521 0.8036670141158531 0.11927514867132136 0.09323358800411644 2.2129336007512355 0.03021400239055225 0.09659129273425436 7.139725859821742e-06 5.146318463273174 0.6568309350321553 SGAHS(ph)SASPPR ddPTM_PC-9_AZD4547_30min_R2 2 SGAHSSASPPR 11 0 P18615;P18615-3;A0A0A0MT02;P18615-4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 1 SGAHS(0.933)S(0.059)AS(0.009)PPR;S(0.287)GAHS(0.31)S(0.263)AS(0.141)PPR 105.66 0.0014343 42971010.0 0.0 0.0 8736.0 25527.29 11487.34 8824.73 1543.5 13538.0 5885.1 10503.11 True False 0.0 0.0 8620.154931999 19642.36768319899 9892.521126921894 8272.918238060405 1680.8685098442957 11446.01317229148 6196.1743713302285 10135.399315797875 0.0 0.0 0.8504997843116957 1.937996429265768 0.9760366433222408 0.8162399901862325 0.16584137017910625 1.129310529921675 0.6113399362245507 1.0 13.307115308963313 -5.27996028919807 5.7046942389090765 0.9491013755648927 8.170587742095036e-09 0.44351329148671004 0.4199242824779018 0.1513665692994935 18.167057946291635 0.11790454331180363 0.27022783431880376 5.248554495261868e-06 5.27996028919807 -0.949101367394305 SGAHSSAS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 3 SGAHSSASPPR 11 0 P18615;P18615-3;A0A0A0MT02;P18615-4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 1 SGAHSSAS(1)PPR;SGAHS(0.001)S(0.001)AS(0.998)PPR;SGAHS(0.03)S(0.03)AS(0.939)PPR 155.88 0.00069335 65691830.0 5319.09 9866.5 35028.31 96501.5 43633.6 39894.8 17200.190000000002 61974.2 20370.170000000002 37129.75 True False 7010.449976054956 13055.653175076537 34563.81172230882 74254.57010831263 37575.827810760304 37400.17184931123 18730.973588816818 52397.51141544001 21446.89559967374 35829.84875391634 0.19565949117462259 0.36437924326011856 0.9646652979111686 2.0724220919351866 1.0487297356133305 1.04382723204276 0.5227756811775391 1.4623983421005302 0.5985762247274212 1.0 15.128874333161303 -5.2703076416294765 4.116909385106603 1.1235887449517732 0.25368419062162534 0.3855329746747671 0.4115566482315777 0.20375975072693772 8.424955637838536 0.11080806060954566 0.2816767264072304 5.366515133101594e-06 5.2703076416294765 -0.8699045543301478 SGAHSSAS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SGAHSSASPPR 11 0 P18615;P18615-3;A0A0A0MT02;P18615-4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 1 SGAHSS(0.001)AS(0.999)PPR;SGAHS(0.015)S(0.01)AS(0.975)PPR;SGAHS(0.047)S(0.047)AS(0.905)PPR;SGAHS(0.025)S(0.025)AS(0.95)PPR 132.56 0.00010194 30338890.0 8407.369999999999 11740.7 74987.4 41216.5 70390.5 72787.8 39589.5 33236.3 55127.2 26055.76 True False 9830.571687873387 12906.239104416833 76775.38400729831 38907.27313069591 56597.986827432156 68970.67963240124 35839.29595684105 32363.88234177075 55933.331009583875 30779.46303071731 0.3193873680662547 0.419313328875707 2.494370481079477 1.264066013493062 1.8388230740396108 2.240801912741942 1.164389902483813 1.0514765091734128 1.8172289410560376 1.0 14.909680442610028 -5.157894459558381 8.61977351164585 1.6125950986846829 0.3511587989097009 0.5189670697409495 0.47755126359703476 0.24802373897392357 18.782641503348554 0.1203349875097707 0.32092191914599616 6.951932400370084e-06 5.157894459558381 -1.261436299774982 SGAHSSAS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 2 SGAHSSASPPR 11 0 P18615;P18615-3;A0A0A0MT02;P18615-4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 1 SGAHS(0.003)S(0.002)AS(0.995)PPR;SGAHS(0.001)S(0.003)AS(0.997)PPR 132.86 8.6964e-05 25245000.0 29998.0 14167.7 125587.0 26071.7 65312.0 92009.0 38694.0 43364.0 134446.0 33681.4 True False 29570.223019040535 14134.895561110896 115261.72163983922 27989.0997906416 61470.476568332444 88073.98955345484 40697.38598880392 45378.84974806503 119303.27570085564 39503.18511235555 0.748552880861036 0.3578166044309646 2.9177829917261127 0.7085276721619936 1.556089120244284 2.2295414737559383 1.0302304959220834 1.148739009753209 3.0200925662457716 1.0 15.269681360954214 -5.194702975627628 24.99999526764367 1.6609422909082678 0.5531815175558767 0.2640817097545147 0.7643080813198248 250.12281434732122 93696.43348184174 0.1849560745051274 0.48934782730583504 6.387001591467092e-06 5.194702975627628 -1.107760773352391 SGAMS(ph)PMSWNSDASTSEAS ddPTM_PC-9_AZD4547_30min_R2 2 SGAMSPMSWNSDASTSEAS 19 0 Q13158 Q13158 FADD FAS-associated death domain protein 1 S(0.033)GAMS(0.963)PMS(0.004)WNSDASTSEAS;S(0.033)GAMS(0.963)PMS(0.004)WNSDASTSEAS 103.04 0.0020886999999999998 0.0 17379.0 14925.7 22885.9 27534.4 21973.4 20691.0 13788.8 24393.3 19641.4 22362.2 True False 22905.160494343796 19750.140637028293 22582.41801261858 21186.769482239364 18922.77269849291 19397.18849910511 15015.976487554914 20623.87598726973 20679.604305287183 21579.30618452394 1.0614410073466922 0.9152352011758621 1.0464848971286222 0.9818095772436793 0.8768943976550915 0.8988791545585565 0.6958507543826382 0.9557247026811541 0.9583071915499305 1.0 14.397360859748972 -6.2050744175865775 4.713098945721262 0.8852049677308786 1.0002901320277644 0.2559673843312239 0.08534856859495464 0.29238809541443206 13.84667778875708 0.026017780419871128 0.033503824653110185 6.236279659124532e-07 6.2050744175865775 0.11508516429688576 SGAMS(ph)PMSWNSDASTSEAS ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGAMSPMSWNSDASTSEAS 19 0 Q13158 Q13158 FADD FAS-associated death domain protein 1 S(0.108)GAMS(0.837)PMS(0.055)WNSDASTSEAS 77.137 0.024369 0.0 16755.0 17615.0 17225.0 20112.0 22184.0 17398.0 17813.0 17982.0 19306.0 16259.0 True False 19591.290573665574 19363.70078652061 17635.709326176282 18985.189843983757 17837.20444917647 16485.618252571414 16125.623685048053 17509.991553503907 19588.31372663635 19206.627993826827 1.0200275956801153 1.0081780514905723 0.9182095541104117 0.9884707430208862 0.9287004702183796 0.8583296483833618 0.8395864016437953 0.911664013023617 1.0198726050680107 1.0 14.229316634440424 -5.228138776095288 5.358086640503893 0.9256506487980035 1.0160894614813096 0.24734061949836506 0.055329925134234154 0.2567230673010811 20.834541550246662 0.015177411813935084 0.040236784228944514 5.913726345401592e-06 5.228138776095288 0.09043881268330611 SGAQAS(ph)STPLSPTR ddPTM_PC-9_AZD4547_30min_R2 1 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 S(0.004)GAQAS(0.575)S(0.331)T(0.09)PLSPTR 78.40100000000001 0.013994 6939400.0 25469.0 19376.0 36082.0 44292.0 36205.0 33187.0 28306.0 39634.0 35724.0 39152.0 True False 33567.61221189033 25638.91308166857 35603.52910444001 34081.1637045785 31178.560693790467 31111.811643700217 30825.17916401208 33509.47599871477 37612.29770800854 37781.300396941304 0.8884715946571256 0.678613833094645 0.9423584876745639 0.9020643372915148 0.8252378919258856 0.8234711700452472 0.8158845471212955 0.8869328383791583 0.995526816516182 1.0 15.205384738341154 -8.159564417416801 2.9441616929504333 1.0025056092101579 0.8387167800792632 0.46956294777455154 0.06632493473584246 0.23934315958107358 3.72281139038188 0.05648935496134261 0.017662232365947148 6.9252520192164455e-09 8.159564417416801 -0.16378882913089465 SGAQAS(ph)STPLSPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 SGAQAS(0.589)S(0.314)T(0.097)PLS(0.001)PTR;SGAQAS(0.432)S(0.432)T(0.136)PLSPTR;S(0.029)GAQAS(0.436)S(0.257)T(0.257)PLS(0.021)PT(0.001)R;SGAQAS(0.428)S(0.428)T(0.144)PLS(0.001)PTR 130.64 1.8840999999999998e-05 23806300.0 44165.9 53694.0 56964.0 72080.0 66687.0 56013.5 67095.0 63404.3 57634.1 52333.6 True False 51642.3145537127 59024.38546871628 58322.23779717298 68041.59128651292 53620.161066635046 53076.053453868815 60739.275874265964 61740.00430740895 58476.889679495056 61821.267407450316 0.8353486869389075 0.9547585797570212 0.9434008755075174 1.1006178640445177 0.8673416659874734 0.8585403645003955 0.9824980693771096 0.9986855154633796 0.9459024722687549 1.0 15.915815610964936 -4.7595192102907955 5.4086352699086895 0.9599746537202124 0.8287789020313769 0.25059379029436 0.065369439624537 0.24530992288370865 21.91183595080483 0.016910102391391943 0.1210964300725431 1.7397257424747845e-05 4.7595192102907955 -0.13119575168883546 SGAQAS(ph)STPLSPTR ddPTM_PC-9_Lapatinib_30min_R1 4 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 S(0.013)GAQAS(0.595)S(0.312)T(0.08)PLSPTR;SGAQAS(0.901)S(0.075)T(0.022)PLS(0.002)PT(0.001)R;S(0.015)GAQAS(0.527)S(0.172)T(0.275)PLS(0.003)PT(0.007)R;S(0.011)GAQAS(0.469)S(0.469)T(0.051)PLSPTR 123.92 0.00018834 28973800.0 91250.0 83606.0 88523.0 72820.0 84487.0 81460.0 72732.0 66149.0 87936.0 69588.0 True False 89948.75826679931 83412.41544373748 81244.98064866164 78175.42572039865 79517.6407678329 77976.14569253476 76497.7070795909 69222.52402879692 78031.72167286825 81616.19307981835 1.1020945093436538 1.0220081615686545 0.9954517306290718 0.9578420993484134 0.9742875496541095 0.9554004266809686 0.9372859011541776 0.8481469352668684 0.9560813697418529 1.0 16.31656779839154 -3.0732378690487225 0.4918961543852218 0.9295985210580066 1.9648662749968613 0.6345439353350601 0.037244554697607395 13.389240740977938 0.6502580550293486 0.02151571613283578 11.518800210722107 0.0008448160010993676 3.0732378690487225 1.0352677539388546 SGAQASS(ph)TPLSPTR ddPTM_PC-9_AZD4547_30min_R2 5 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 SGAQAS(0.196)S(0.608)T(0.196)PLSPTR;S(0.004)GAQAS(0.289)S(0.53)T(0.175)PLS(0.002)PTR;SGAQAS(0.191)S(0.617)T(0.191)PLS(0.001)PTR;SGAQAS(0.114)S(0.771)T(0.114)PLSPTR;S(0.001)GAQAS(0.19)S(0.613)T(0.19)PLS(0.006)PTR 137.19 3.0001e-05 118792500.0 121591.8 118535.0 161535.0 228091.0 193122.0 170716.0 140744.0 185669.0 152932.0 167082.0 True False 160255.4631334454 156849.12067173753 159392.94035490582 175508.1439208214 166310.34382837225 160041.10153270615 153269.94334274423 156978.12229917172 161015.67330313398 161232.51003580252 0.9939401371216005 0.9728132411813745 0.9885905784107174 1.0885406664068487 1.031493858102452 0.9926106186473694 0.9506143848328718 0.9736133380564125 0.9986551302053142 1.0 17.29878314472066 -6.977176953086278 8.184585601940716 0.9775324489064079 1.0150850194296006 0.20342503637130405 0.03208150479436497 0.3330660145941084 97.99235376449973 0.012667962881184807 0.011041610609884801 1.0539573744469944e-07 6.977176953086278 0.03755257052319272 SGAQASS(ph)TPLSPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 S(0.012)GAQAS(0.181)S(0.623)T(0.181)PLS(0.003)PTR;S(0.002)GAQAS(0.194)S(0.611)T(0.194)PLSPTR;S(0.055)GAQAS(0.177)S(0.584)T(0.177)PLS(0.005)PT(0.002)R;S(0.006)GAQAS(0.084)S(0.718)T(0.193)PLSPTR 168.47 0.00015692 141116000.0 184345.0 206624.0 222462.0 245331.0 269353.0 231092.0 261721.0 227099.0 224349.0 182158.0 True False 215550.96752028514 227136.2651895566 227766.3377718336 231585.8994438332 216575.21321668953 218973.1287057845 236928.8921840492 221137.89188127997 227629.67969839156 215181.80343806502 1.0017155915431593 1.0555551703744894 1.058483264535845 1.0762336579751257 1.0064755000486163 1.0176191722866135 1.101063790704048 1.0276793313749193 1.057848182613217 1.0 17.715196557909323 -10.35195771110999 6.494315308431157 0.9999999999629047 1.0456214962255221 0.1663967466708428 0.02998455635553595 4.55289996135909e-10 1.3195156104160407e-10 0.028753967771593433 0.0069738612859614035 4.4467456499886396e-11 10.35195771110999 0.04562149626261747 SGAQASS(ph)TPLSPTR ddPTM_PC-9_Lapatinib_30min_R1 4 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 S(0.019)GAQAS(0.199)S(0.583)T(0.199)PLSPTR;S(0.031)GAQAS(0.16)S(0.51)T(0.16)PLS(0.069)PT(0.069)R;S(0.047)GAQAS(0.11)S(0.421)T(0.421)PLSPTR;SGAQAS(0.229)S(0.738)T(0.034)PLSPTR 138.98 1.8840999999999998e-05 142336200.0 212903.0 188733.0 212955.0 168226.0 206199.0 200867.0 176186.0 189953.0 228656.0 167164.0 True False 209866.96417837188 188296.00033422103 195446.66193007198 180597.90122548462 194070.78022283156 192276.38665384706 185308.04899528122 198778.90983751984 202902.3534255751 196058.07466797088 1.0704326487638252 0.9604093106244407 0.9968814712735787 0.9211449287734339 0.9898637459920747 0.9807113885998922 0.9451691765774244 1.0138777001363333 1.0349094459342987 1.0 17.58092153502912 -7.927446562713787 10.760231071609194 1.0197624216217978 0.9785912225014176 0.1556226365977863 0.037773994519373265 0.7129946406866463 101.3059802635839 0.020057573642397165 0.009626816613663845 1.1818257200429586e-08 7.927446562713787 -0.04117119912038014 SGAQASST(ph)PLSPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 S(0.002)GAQAS(0.048)S(0.189)T(0.761)PLSPTR 79.346 0.038024 0.0 10500.0 11363.0 11567.0 13473.0 15601.0 13036.0 13530.0 12569.0 13380.0 9254.8 True False 12277.442615546901 12491.043544549162 11842.80114809179 12718.151490055341 12544.096042715568 12352.36921143356 12248.340451282775 12239.07706795632 13575.657187526891 10932.621979043508 1.123009890864355 1.1425478323949148 1.0832535114442796 1.1633212521602296 1.147400510761376 1.129863379078828 1.1203479343529243 1.119500618554005 1.241756754559863 1.0 13.41635182470577 -5.781002955951957 24.99194587800452 1.13682014526926 1.1188981082988727 0.009046689706339817 0.05745620105215776 1245.0869761751985 1590554.7931609051 0.015269042062239708 0.022679939199433966 1.6557586937895968e-06 5.781002955951957 -0.01792203697038719 SGAQASSTPLS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 7 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 SGAQASS(0.006)T(0.006)PLS(0.986)PT(0.002)R;S(0.018)GAQAS(0.26)S(0.086)T(0.029)PLS(0.596)PT(0.011)R;SGAQASSTPLS(0.798)PT(0.202)R;SGAQAS(0.015)S(0.015)T(0.006)PLS(0.926)PT(0.038)R;SGAQASSTPLS(0.912)PT(0.087)R;SGAQASSTPLS(0.947)PT(0.053)R;SGAQASS(0.003)T(0.003)PLS(0.949)PT(0.045)R 133.9 1.4136e-05 2382141800.0 221075.4 174246.2 241130.7 356785.0 310521.3 268600.6 231512.1 289104.6 226897.9 269669.2 True False 291372.77854601754 230567.87657984268 237933.1493659997 274533.7305233008 267410.7774827991 251804.96202081733 252116.2284016353 244430.12703280096 238891.2597727566 260228.16338891615 1.1196819542954508 0.8860219953797023 0.9143251301758754 1.054973170267527 1.0276012173330693 0.9676314767071919 0.968827605430403 0.9392915964575874 0.9180069392248251 1.0 17.989417581699186 -7.266478701118619 2.367491867073042 0.9485818484887755 0.9919348526181975 0.08086601708402308 0.06552992205573624 0.9021780730895632 9.933393742920387 0.03215572443502977 0.021087597542174277 5.414037990202622e-08 7.266478701118619 0.043353004129422 SGAQASSTPLS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 SGAQASSTPLS(0.983)PT(0.017)R;S(0.008)GAQAS(0.001)S(0.001)TPLS(0.985)PT(0.005)R;SGAQASSTPLS(0.5)PT(0.5)R 154.81 2.2944000000000003e-05 550876200.0 390482.4 417204.6 487272.8 501692.7 512382.6 380590.3 486320.8 567446.6 472215.0 388434.4 True False 456583.35794105066 458621.9154788536 498891.2315443843 473584.4845286796 411984.90769927023 360631.47467706865 440252.973166311 552551.7280093695 479120.2510319889 458854.4818749804 0.9950504484021832 0.9994931587130272 1.0872536964350985 1.0321016863418424 0.8978552547112741 0.7859386557660919 0.9594609850324235 1.2041981713930776 1.044166004599537 1.0 18.807677173690195 -7.7206561206832 24.92302876428013 1.0931366846856896 0.964388512512168 0.2600095380052345 0.09030834155848287 191.28905937918432 116898.37685937161 0.046739023738524205 0.026984391179791237 1.9025841714684215e-08 7.7206561206832 -0.12874817217352164 SGAQASSTPLS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 1 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 SGAQASSTPLS(0.974)PT(0.026)R 91.845 0.0043793 45052000.0 38200.0 38904.0 47986.0 36813.0 44798.0 47667.0 34917.0 37509.0 48637.0 42518.0 True False 37655.26099497795 38813.92017825466 44040.77631131666 39520.35082456801 42163.06971625671 45628.393527204156 36724.831409806866 39251.80507333666 43158.9888896845 49867.17964832622 0.7551111023428781 0.7783460073735579 0.8831615628134861 0.7925122516106543 0.8455074061456752 0.9149984789391565 0.7364529469843303 0.7871270312487813 0.8654788418765752 1.0 15.605802989963058 -8.621839212790075 4.218519483250764 0.999968852250464 0.8147037189404165 0.5367569780314704 0.05288574445784143 0.43990416739920385 17.03133757552005 0.05233316931536968 0.013679414974485661 2.388695476954706e-09 8.621839212790075 -0.18526513331004746 SGAQASSTPLSPT(ph)R ddPTM_PC-9_AZD4547_30min_R2 5 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 SGAQASSTPLS(0.319)PT(0.681)R;SGAQASSTPLS(0.061)PT(0.939)R;SGAQASSTPLS(0.133)PT(0.867)R;SGAQAS(0.001)S(0.007)T(0.007)PLS(0.238)PT(0.747)R;SGAQASSTPLS(0.088)PT(0.912)R 135.61 3.7709e-05 2757788000.0 836212.0 847777.0 1077390.0 1498864.0 1262499.0 960155.0 1025694.0 1336575.0 836193.0 988189.0 True False 1102110.0217098917 1121804.3360671832 1063103.1046458802 1153324.0620179574 1087222.806169032 900116.3560658387 1116978.7789674315 1130038.045188025 880392.4548581572 953592.8038913223 1.1557449020300026 1.1763976526347941 1.114839688709562 1.2094513059574197 1.1401331907417989 0.9439210870643502 1.1713372567508695 1.1850320604105686 0.9232373097464067 1.0 19.86301382325128 -7.664698971674394 0.3245975326671855 0.9808632294929198 1.184837415295825 0.302159811482257 0.08380344025055911 2.0295071039493573 0.6718003177731463 0.13143865665381493 0.14480649027828693 2.1642181173140702e-08 7.664698971674394 0.20397418580290516 SGAQASSTPLSPT(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 10 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 SGAQASS(0.001)T(0.001)PLS(0.325)PT(0.674)R;SGAQASSTPLS(0.076)PT(0.924)R;SGAQASSTPLS(0.218)PT(0.782)R;SGAQASSTPLS(0.122)PT(0.877)R;SGAQASSTPLS(0.045)PT(0.955)R;SGAQASSTPLS(0.093)PT(0.905)R;S(0.001)GAQASSTPLS(0.147)PT(0.852)R;SGAQASSTPLS(0.044)PT(0.956)R;SGAQAS(0.011)S(0.011)T(0.011)PLS(0.459)PT(0.506)R;SGAQASSTPLS(0.047)PT(0.953)R 135.55 3.7709e-05 4436139300.0 615297.4 614962.3 735242.2 873746.0 973815.0 823168.4 832883.0 983730.0 743450.4 624513.3 True False 719455.0971424014 676011.6929997453 752773.1624695705 824792.844342751 783002.9413394687 779999.9999988503 753986.2926892663 957908.1298480934 754321.9556300275 737732.6176454363 0.9752247358109638 0.9163369991113027 1.0203875285765973 1.1180105428646736 1.0613641346623905 1.0572936336857592 1.022031932240851 1.2984489324945048 1.0224869249207633 1.0 19.492738497912242 -5.517587767796608 3.9381974033678118 1.090373890645293 0.947646359966638 0.31123138354894453 0.08084842734937192 0.23591701992417582 8.263328510138942 0.021881862908769905 0.04420403732017875 3.0367723200465405e-06 5.517587767796608 -0.14272753067865507 SGAQASSTPLSPT(ph)R ddPTM_PC-9_Lapatinib_30min_R1 7 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 SGAQASSTPLS(0.128)PT(0.872)R;SGAQASSTPLS(0.132)PT(0.868)R;SGAQASSTPLS(0.011)PT(0.989)R;SGAQASSTPLS(0.242)PT(0.758)R;SGAQASSTPLS(0.209)PT(0.79)R;SGAQASSTPLS(0.134)PT(0.866)R;SGAQASSTPLS(0.128)PT(0.872)R 184.92 1.521e-05 4209003600.0 807928.1 606115.8999999999 844079.5 700379.2 803105.9 826430.8 714599.1 735206.7 914186.2 694930.7999999999 True False 796406.897138134 604712.4758732002 774682.5417510963 751887.4227645198 755868.7899289505 791086.281188289 751597.5448377504 769367.0872860156 811220.9233485395 815048.6628429126 0.9771280335093666 0.7419341978477041 0.9504739742152104 0.9225061729957514 0.927390994413093 0.9706000601595467 0.9221505157939368 0.9439523335974096 0.9953036675368292 1.0 19.63652667310111 -6.263501329867841 0.3269510890939975 0.997643256611602 0.83976390964999 0.24916639394118956 0.06057900597075281 3.654308237627227 0.6464627209276825 0.06958964372390608 0.21399159193162717 5.45128226430751e-07 6.263501329867841 -0.157879346961612 SGAQASSTPLSPTR ddPTM_PC-9_AZD4547_30min_R2 1 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 132.06 0.00040401 0.0 12422.0 10460.0 11368.0 19864.0 16336.0 13594.0 13064.0 13493.0 12574.0 11500.0 False True 16371.937606348953 13840.990443551462 11217.25289228075 15284.661695740697 14068.028379885685 12743.96503102001 14226.670691678572 11407.966888294353 13238.635969670238 11097.38850032757 1.475296427250942 1.2472295119831938 1.0108011350553008 1.3773205917130438 1.2676881934403241 1.1483751362443368 1.281983656898975 1.0279866193706397 1.1929505729460101 1.0 13.437932592980864 -1.5228787695848027 0.05600900844080304 0.6596958038929943 2.2780798417240637 0.35734655821798567 0.12125337175757349 480.41424929684126 2.026678658744487 12.617283025404799 64.7576026027864 0.02999999832110707 1.5228787695848027 1.6183840378310694 SGASSLWDPAS(ph)PAPTSGPRPR ddPTM_PC-9_AZD4547_30min_R2 1 SGASSLWDPASPAPTSGPRPR 21 1 A0A087WVG4;A2AB22;A2AB23;E9PQZ5;A0A140TA01;E9PQT8;O43189-2;O43189 A0A087WVG4 PHF1 PHD finger protein 1 1 SGASSLWDPAS(0.977)PAPT(0.018)S(0.005)GPRPR 66.711 0.0018437999999999998 2697000.0 12444.0 12117.0 11880.0 17940.0 16622.0 15152.0 10826.0 12356.0 12792.0 12222.0 True False 16400.933148720535 16033.583289150378 11722.463437745895 13804.210170237027 14314.322216605036 14204.543044726723 11789.493027259045 10446.664112633585 13468.159004614416 11794.111500087276 1.3906035353828194 1.3594566482631378 0.993925098779942 1.1704323950248288 1.2136838130196677 1.2043758484580724 0.9996084085835378 0.8857525310453679 1.141939263887301 1.0 13.52577911794881 -1.5228787452981345 0.3212523459106473 1.0121110562327444 4.829681989824761 0.5244282354716227 0.10829282736189642 48.580973969027475 0.6932022483059799 0.10870512901235342 109.10633417856585 0.02999999999877063 1.5228787452981345 3.817570933592016 SGAVQGAGSLGPGS(ph)PVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGAVQGAGSLGPGSPVR 17 0 Q9P270 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 SGAVQGAGSLGPGS(1)PVR 101.54 0.0078697 0.0 51228.0 27070.0 31705.0 67845.0 62165.0 63239.0 50885.0 51434.0 56297.0 41066.0 True False 59899.8886008797 29757.330700602462 32460.96744188208 64043.86460645775 49984.21450518643 59922.63551410299 46064.80442450284 50083.911998827694 57120.237121539714 48510.940721722865 1.234770707591266 0.6134148350431253 0.6691473502460091 1.3201942418275832 1.0303699281346619 1.235239610335366 0.9495755748944967 1.032425082954544 1.1774712316795304 1.0 15.566022536023125 -5.752876127862438 24.99992779206536 1.1034765581535535 0.8165413687404312 0.2964359439589094 0.18774729518600014 218.1575292553803 636891.802707892 0.04992239450308535 0.08475562459641363 1.7665416126761467e-06 5.752876127862438 -0.28693518941312235 SGAYLIPLLER ddPTM_PC-9_Lapatinib_30min_R1 1 SGAYLIPLLER 11 0 Q8IV96;P26196 Q8IV96 DDX6 Probable ATP-dependent RNA helicase DDX6 0 94.40899999999999 0.025692000000000003 0.0 7860.3 8560.5 7791.1 7176.8 10290.0 10496.0 9278.0 7921.8 9140.4 6314.0 False True 7748.2106805975245 8540.678688205555 7150.545832515717 7704.605813102975 9684.762430918376 10047.11054737103 9758.369442397347 8289.875747952716 8110.911899320931 7405.366487123846 1.0462967219880073 1.15330938759827 0.9655897307646825 1.0404084425125257 1.3078032596709226 1.3567337369245052 1.31774294484477 1.1194416592840906 1.0952748811856725 1.0 12.854355420050979 -6.243650375223301 24.182934142918366 1.2192453886100219 1.0525508294193746 0.2824895299743939 0.11302495481611344 675.7728844962891 918665.6915568347 0.035058748326979715 0.04514677878162792 5.706234625907149e-07 6.243650375223301 -0.16669455919064724 SGCIVNNLAEFTVDPK ddPTM_PC-9_Lapatinib_30min_R1 2 SGCIVNNLAEFTVDPK 16 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 167.32 3.723e-05 8437500.0 40952.0 47929.0 46033.0 50283.0 46487.0 33772.8 45847.0 44109.0 40473.4 44525.0 False True 40368.01697032298 47818.02334524896 42248.344432518665 53980.97955917079 43752.72605695846 32328.416072242035 48220.73332890616 46158.46516782124 35914.85948820354 52221.086924166775 0.7730213855744459 0.9156841835691442 0.8090284389114669 1.0337008043811813 0.8378363728907883 0.6190682342400873 0.9233958189903293 0.883904719081213 0.6877463033344664 1.0 15.672344865614336 -4.714938751129159 21.901521399230205 0.8511883766072817 0.7730165709068595 0.03902748309671278 0.1218394363010755 10417.134868947363 4904713.995917297 0.030010588573821637 13.095867601716977 1.9277967726197718e-05 4.714938751129159 -0.07817180570042226 SGCNSASST(ph)PDSTR ddPTM_PC-9_AZD4547_30min_R2 2 SGCNSASSTPDSTR 14 0 Q92547;A0A2R8YD63 Q92547 TOPBP1 DNA topoisomerase 2-binding protein 1 1 S(0.036)GCNS(0.019)AS(0.034)S(0.115)T(0.796)PDSTR;S(0.001)GCNS(0.014)AS(0.21)S(0.11)T(0.653)PDS(0.012)T(0.001)R 104.16 0.0033781999999999996 0.0 7676.3 7220.5 8757.400000000001 16527.0 14187.8 10619.8 11629.5 13615.5 9173.6 11766.0 True False 10117.2037230411 9554.385420426699 8641.271154016495 12716.95548960464 12218.068869254534 9955.74222719039 12664.502970673291 11511.537328064314 9658.497767724417 11354.07592129168 0.891063596295746 0.8414938817266389 0.7610721659709875 1.1200343892149978 1.0760953999208913 0.8768430206214254 1.1154146809010004 1.0138682714352258 0.8506634828478081 1.0 13.470922673175071 -5.753728163053758 24.9999556673165 1.0100407992897524 0.8322382750433193 0.45102787873025674 0.08912601714472167 160.96642099833127 521851.2921270806 0.024534399455952902 0.04149134522319765 1.7630792612564123e-06 5.753728163053758 -0.17780252424643317 SGCNSASST(ph)PDSTR ddPTM_PC-9_Lapatinib_30min_R1 1 SGCNSASSTPDSTR 14 0 Q92547;A0A2R8YD63 Q92547 TOPBP1 DNA topoisomerase 2-binding protein 1 1 SGCNSAS(0.007)S(0.079)T(0.907)PDS(0.005)T(0.002)R 98.421 0.0074077 0.0 958.2 1101.5 2282.3 2084.1 2249.8 3626.8 2456.2 2305.5 4529.0 2357.0 True False 944.5358922876412 1098.949544425958 2094.6581039327725 2237.3716663537944 2117.471187276985 3471.690218483734 2583.3700177210985 2412.6219466415446 4018.8963275156975 2764.404309494916 0.3416779119622402 0.3975357514280344 0.7577249452036512 0.809350375655645 0.7659773861602277 1.2558547266619065 0.9345123681250177 0.8727456900406708 1.4538019325581175 1.0 11.43275291798816 -5.236990665457897 0.5553698797418006 1.1129342185241398 1.2024724564683363e-19 0.7068473252227253 0.17452392943282266 1.4284481515316156 0.4783070796143207 0.10426337216659746 0.9635893140343559 5.794411505563123e-06 5.236990665457897 -1.1129342185241398 down SGCS(ph)DLEEAVDSGADKK ddPTM_PC-9_AZD4547_30min_R2 1 SGCSDLEEAVDSGADKK 17 1 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 S(0.194)GCS(0.806)DLEEAVDSGADKK 113.81 8.0435e-05 4527100.0 14431.0 19590.0 18650.0 24034.0 22930.0 15494.0 23030.0 17539.0 21222.0 21096.0 True False 19019.75781655304 25922.084396670474 18402.688814306475 18493.332621598467 19746.565300610855 14525.157730662348 25079.625384978382 14828.750556124998 22343.751594428308 20357.43546112266 0.9342904636920386 1.2733472468167628 0.9039787378646374 0.908431352117798 0.9699927743021264 0.713506264499847 1.2319638901900911 0.7284193819228364 1.097572021637941 1.0 14.313268208126326 -5.301612501453629 24.954317951179668 0.9362109411475004 1.1038191790181249 0.12936102534742644 0.16455472412605485 783.9927787506449 486991.00617712486 0.039531677625789324 0.08229293618020989 4.99329814975807e-06 5.301612501453629 0.1676082378706245 SGCS(ph)DLEEAVDSGADKK ddPTM_PC-9_Lapatinib_30min_R1 2 SGCSDLEEAVDSGADKK 17 1 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 S(0.193)GCS(0.807)DLEEAVDSGADKK;S(0.196)GCS(0.803)DLEEAVDS(0.001)GADKK 115.2 7.1784e-05 11076500.0 73392.0 82420.0 83780.0 75104.0 87672.0 89445.0 87990.0 81544.0 83597.0 64920.0 True False 72345.41662155539 82229.16155386952 76891.93180015223 80627.39869959943 82515.3053297838 85619.64585647892 92545.69166162351 85332.83193100776 74181.42554456387 76141.3354995376 0.9501464105787156 1.0799542852038482 1.0098579345330656 1.0589175796645842 1.0837123461051574 1.124483111502541 1.2154461312565963 1.1207162492116518 0.974259580001908 1.0 16.21639225417333 -6.071551869953916 2.0131717845179744 1.1020078641463005 1.018496634270767 0.15789242756963662 0.07017132110842986 0.5521882621367454 4.444357985301168 0.023513182506865897 0.03526996488455063 8.48102083345576e-07 6.071551869953916 -0.08351122987553339 SGCSEAQPPES(ph)PETR ddPTM_PC-9_AZD4547_30min_R2 1 SGCSEAQPPESPETR 15 0 A0A494BZT8;Q9Y6A5;H0Y8F2;A0A494C117 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 SGCSEAQPPES(0.669)PET(0.331)R 142.35 1.1106e-06 0.0 8241.4 5350.4 9072.2 10253.0 9198.5 8208.4 8599.4 12641.0 10052.0 7293.9 True False 10861.993768230912 7079.812167225403 8951.896700329828 7889.32925727091 7921.447052667634 7695.127450391683 9364.729940754802 10687.623911282066 10583.328198435272 7038.5427810903775 1.5432162744556372 1.005863342373353 1.2718394955813628 1.1208753718832596 1.1254385032579828 1.0932841768135975 1.3304927215778124 1.5184427009515726 1.5036249018572783 1.0 12.781061057259647 -7.4473407268963925 6.000657401230388 1.3911650058353848 1.1831209142251686 0.10270352792386506 0.191372497604029 0.35636257059314846 22.13501998393315 0.07757435585038337 0.05130895966810319 3.569926487180319e-08 7.4473407268963925 -0.2080440916102162 SGCSEAQPPESPET(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 SGCSEAQPPESPETR 15 0 A0A494BZT8;Q9Y6A5;H0Y8F2;A0A494C117 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 SGCSEAQPPES(0.376)PET(0.624)R 84.859 0.014605000000000002 34536000.0 8550.8 9345.9 14305.0 20993.0 16319.0 11373.0 9812.4 16977.0 11460.0 15579.0 True False 11269.776532311116 12366.779405964397 14115.306353279046 16153.388188616816 14053.388536444316 10661.844512122294 10685.684590862431 14353.594742649759 12065.752203946307 15033.58395187854 0.7496400438102377 0.8226101936537289 0.9389182511942038 1.0744868449414786 0.934799618070331 0.7092017809093374 0.7107875690232327 0.9547686558703913 0.8025865450692227 1.0 13.875901363070716 SGCSEAQPPESPET(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGCSEAQPPESPETR 15 0 A0A494BZT8;Q9Y6A5;H0Y8F2;A0A494C117 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 SGCSEAQPPES(0.008)PET(0.992)R 113.33 0.0018657 0.0 5932.6 5491.0 5941.6 7432.9 7871.3 6102.2 5820.7 6902.7 6200.9 4197.7 True False 6936.872005808909 6036.1101912452195 6083.270277643477 7016.458710786939 6328.975269599835 5782.189889690845 5269.321157781346 6721.511439015205 6291.576431549737 4958.709781025085 1.3989267999416757 1.2172743430847468 1.2267848989512586 1.4149766815626115 1.2763350849485453 1.166067413708476 1.0626395555442347 1.3554960334108737 1.2687930347577463 1.0 12.275749075706509 -6.657359686003206 5.188092303033489 1.1864835629384958 1.306069641039229 0.2752535279841001 0.10987011043556434 0.35062822494875295 14.78507574507191 0.03750673971153291 0.037275273650114855 2.2011027378661222e-07 6.657359686003206 0.11958607810073318 SGDAAIVDMVPGKPMCVESFSDYPPLGR ddPTM_PC-9_AZD4547_30min_R2 1 SGDAAIVDMVPGKPMCVESFSDYPPLGR 28 1 Q5VTE0;P68104;A0A087WVQ9 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1 0 75.956 7.2862e-05 4753300.0 9699.0 9226.2 14129.0 17668.0 15632.0 11428.0 12555.0 12859.0 12678.0 14324.0 False True 12783.080248267474 12208.388721825471 13941.6402282754 13594.915567878912 13461.766627961124 10713.405353427726 13672.37067774223 10871.93702042371 13348.133197350024 13822.521119886282 0.9248009199911167 0.8832244578206085 1.0086177555712137 0.9835337164592994 0.9739009628709379 0.7750688358880125 0.9891372607904334 0.7865379206968542 0.9656800725119702 1.0 13.75473315558229 SGDAAIVDMVPGKPMCVESFSDYPPLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGDAAIVDMVPGKPMCVESFSDYPPLGR 28 1 Q5VTE0;P68104;A0A087WVQ9 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1 0 ; 62.1 0.0027063 28254000.0 118845.0 106922.0 96638.0 116251.0 144881.0 129354.0 106259.0 111435.0 104200.0 89258.0 False True 138963.11120425432 117536.50953711908 98942.2164216559 109737.83336082692 116492.60808696055 122570.44852529744 96193.37827146018 108509.9493251423 105723.72787296757 105439.76883406087 1.3179383143655394 1.1147265480266353 0.9383766439906494 1.0407632203132982 1.104826095268612 1.1624688661656353 0.9123064222840579 1.029117860604505 1.0026930923886375 1.0 16.686059586937148 -4.831945888195415 3.2987956771818623 1.0290066130136548 1.3415056922043813 0.6239240965140307 0.06905426558851802 0.19560537456948898 3.4665740007504393 0.018308106599325795 0.1459892217566651 1.472495959633389e-05 4.831945888195415 0.3124990791907265 SGDAAIVDMVPGKPMCVESFSDYPPLGR ddPTM_PC-9_Lapatinib_30min_R1 2 SGDAAIVDMVPGKPMCVESFSDYPPLGR 28 1 Q5VTE0;P68104;A0A087WVQ9 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1 0 ; 83.31200000000001 3.3364999999999997e-06 17886100.0 111820.0 97843.0 82008.0 78889.0 75018.0 85288.0 72496.0 70229.0 90315.0 63783.0 False True 110225.42629472319 97616.45054495621 75265.61880003466 84690.76022598927 70605.58873106264 81640.43105603861 76249.48815434771 73492.09572356945 80142.77364088771 74807.80656449481 1.4734481781616393 1.3048965746749595 1.0061198457295384 1.1321112610483235 0.9438264797964733 1.091335714884958 1.0192718067279511 0.982412118449282 1.0713156463395757 1.0 16.19090120987913 -5.058644355642497 2.374336029996206 1.0301435268508592 1.4849805308679975 0.8799592326774548 0.054436614439116585 0.10160895471358689 0.9942631755202397 0.01377800306450961 0.07420512490092351 8.736865386473433e-06 5.058644355642497 0.45483700401713834 SGDDLFPK ddPTM_PC-9_Lapatinib_30min_R1 3 SGDDLFPK 8 0 O60218 O60218 AKR1B10 Aldo-keto reductase family 1 member B10 0 ;; 98.62899999999999 0.025099 92618500.0 763920.0 532686.0 998880.0 609725.0 682470.0 792130.0 695490.0 699908.0 853050.0 578380.0 False True 753026.3607142284 531452.5982951303 916755.9421883043 654566.2104829737 642328.4563876451 758252.4464452193 731499.0691412941 732428.2808197747 756970.5259852656 678352.2123570945 1.1100816758563534 0.783446399398438 1.3514453487264675 0.9649356168656534 0.9468952038288836 1.1177857647290523 1.078346994107277 1.079716801209773 1.1158960082919067 1.0 19.3716750148807 SGDEMIFDPT(ph)MSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGDEMIFDPTMSK 13 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 SGDEMIFDPT(0.5)MS(0.5)K 59.067 0.044735000000000004 0.0 1130.0 1512.3 2959.0 1332.9 776.35 1810.5 1510.0 1307.5 923.32 969.46 True False 1321.2866814826666 1662.4311495574862 3029.553782069991 1258.2219343201048 624.229790575106 1715.5541927969061 1366.9618685467108 1273.1795104107632 936.8218082501742 1145.2154237588625 1.153745098145725 1.451631819715632 2.6454007859292474 1.0986770770082093 0.5450763040950314 1.4980187632873994 1.1936285874146062 1.1117380049177934 0.8180310785330744 1.0 10.16140329045654 -5.957387586102689 24.9984084803596 1.0430263467427525 1.7456711522928587 0.37496544562578493 0.4220423918292284 153.30514226771692 89934.90677410409 0.120720367998643 0.17905713500425954 1.103093724507589e-06 5.957387586102689 0.7026448055501062 SGDET(ph)PGSEVPGDK ddPTM_PC-9_AZD4547_30min_R2 2 SGDETPGSEVPGDK 14 0 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 S(0.003)GDET(0.996)PGS(0.002)EVPGDK;S(0.001)GDET(0.975)PGS(0.024)EVPGDK 132.24 3.3883e-05 40924000.0 164179.0 189826.0 191807.0 213938.0 186301.0 239166.0 209765.0 226653.0 223245.0 209030.0 True False 216384.50686465684 251183.54225024828 189263.51385553263 164617.89940915088 160436.32193934152 224210.91221192712 228433.67863134967 191628.9868178005 235045.27493629948 201711.92332378015 1.0727402887201904 1.24525877355826 0.9382861991342683 0.8161039600267587 0.795373517319625 1.1115402030649049 1.1324748426729183 0.9500131854387461 1.1652522620540082 1.0 17.621936839556135 -9.52677731774354 15.790077053484653 0.9999999998648347 1.0197111875642506 0.0014978248369439395 0.1411684621717794 0.0 0.0 0.1480179410245687 0.03589962384298485 2.973190128877559e-10 9.52677731774354 0.019711187699415933 SGDET(ph)PGSEVPGDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGDETPGSEVPGDK 14 0 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 S(0.004)GDET(0.881)PGS(0.115)EVPGDK;SGDET(0.83)PGS(0.17)EVPGDK 86.214 0.016112 7929700.0 43719.0 68973.0 51614.0 50914.0 59742.0 39913.0 57296.0 37918.0 38006.0 40231.0 True False 51119.76321039 75820.18361332318 52844.673507185 48061.45364541512 48035.98396153539 37819.89201717918 51868.50809288233 36922.69267744193 38561.76584971204 47524.56183157925 1.0756493324767868 1.595389430038721 1.1119444655683417 1.0112971439008431 1.0107612171526916 0.7957967535020705 1.091404235912736 0.7769181083308261 0.8114070780151499 1.0 15.536385705080367 -5.651845501644299 2.380995749113728 0.9152283204465873 1.3391346337980075 0.5186350044584669 0.15521717067261293 0.20770117357892176 2.37677874821136 0.043282994213398894 0.08882920668691552 2.229228046319911e-06 5.651845501644299 0.42390631335142015 SGDET(ph)PGSEVPGDK ddPTM_PC-9_Lapatinib_30min_R1 3 SGDETPGSEVPGDK 14 0 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 S(0.001)GDET(0.996)PGS(0.003)EVPGDK;S(0.001)GDET(0.955)PGS(0.043)EVPGDK;SGDET(0.758)PGS(0.242)EVPGDK 155.09 0.00048722 31575700.0 64810.0 94702.0 92408.0 86218.0 107012.0 95327.0 91285.0 96449.0 87323.0 75443.0 True False 63885.7975153016 94482.72333747352 84810.57094519539 92558.75933481644 100717.76455368682 91250.0864280905 96011.29063906461 100930.37264438513 77487.76418804447 88483.22202852134 0.7220102981185393 1.0678038296008063 0.9584932487862826 1.046060001126331 1.138269631741279 1.0312699327187396 1.0850790515756388 1.1406724385765656 0.8757339799749535 1.0 16.43311630038354 -4.758945852682941 24.998413019448083 1.0446872223455612 0.7220098738851628 0.605768877654126 0.07634800308077912 43.98661194674055 440888.0842304037 0.018401206089802384 0.12117479855214727 1.742024053329865e-05 4.758945852682941 -0.3226773484603984 SGDETPGS(ph)EVPGDK ddPTM_PC-9_Lapatinib_30min_R1 1 SGDETPGSEVPGDK 14 0 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 SGDET(0.231)PGS(0.769)EVPGDK 160.65 0.00048858 26595000.0 68090.0 104500.0 94492.0 76079.0 99733.0 90200.0 111830.0 105280.0 89417.0 73007.0 True False 67119.02411382325 104258.03667046104 86723.23250966817 81674.1034521042 93866.90102262225 86342.35626646978 117620.01021160767 110171.69314353589 79345.9158572468 85626.16267428717 0.7838611706697273 1.2175955737622803 1.0128123204534358 0.9538451905498068 1.0962408928645089 1.0083641911515635 1.3736457005439062 1.2866592371144472 0.9266550476992673 1.0 16.385764052268108 SGDETPGS(ph)EVPGDKAAEEQGDDQDSEK ddPTM_PC-9_Lapatinib_30min_R1 2 SGDETPGSEVPGDKAAEEQGDDQDSEK 27 1 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 S(0.022)GDET(0.435)PGS(0.543)EVPGDKAAEEQGDDQDSEK;S(0.002)GDET(0.059)PGS(0.94)EVPGDKAAEEQGDDQDSEK 119.43 2.0422e-12 9868900.0 71865.0 47991.0 51296.0 50451.0 50801.0 51616.0 41953.0 38741.0 52793.0 41998.0 True False 70840.19192157303 47879.87978805828 47078.640888286136 54161.334839602314 47812.985058608814 49408.50400277278 44125.121062394435 40541.04829097378 46846.896405064304 49257.298341182664 1.4381664099986886 0.9720362545346348 0.9557698548993497 1.0995595914427065 0.9706781871679248 1.0030697108181368 0.8958087948055942 0.8230465262257092 0.9510650803577855 1.0 15.588049880779229 -4.761401652571619 6.765725436159798 0.9605441536253069 1.4497905322284552 0.8151633017335662 0.06782487339411995 0.05101998478190471 12.2609008412368 0.01862978948691945 0.11482810925534823 1.7322012490669992e-05 4.761401652571619 0.48924637860314835 SGDNLAEENSRDENR ddPTM_PC-9_Lapatinib_30min_R1 1 SGDNLAEENSRDENR 15 1 Q9H4L5-5;Q9H4L5;Q9H4L5-6;Q9H4L5-2 Q9H4L5-5;Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 0 100.11 0.0025033 4041700.0 14820.0 11199.0 14668.0 10624.0 14142.0 13456.0 7800.4 11591.0 15208.0 11305.0 False True 14608.664082344845 11173.069403564516 13462.053660117392 11405.324400625072 13310.19536424176 12880.518247468039 8204.266544349668 12129.560175025874 13495.114892660353 13259.054187034377 1.1017877954394524 0.8426746920221744 1.015310252919965 0.8601914012673686 1.0038570758129484 0.9714507585362689 0.6187671027374162 0.9148133798930393 1.0178037363974886 1.0 13.694690246376885 SGEHDFGAAFDGDGDR ddPTM_PC-9_AZD4547_30min_R2 2 SGEHDFGAAFDGDGDR 16 0 A0A3B3ITK7;P36871;P36871-2;P36871-3 A0A3B3ITK7 PGM1 Phosphoglucomutase-1 0 ; 134.02 1.0389000000000002e-05 8116100.0 39536.0 47787.0 84655.0 92025.0 81943.0 80629.0 58474.0 116942.0 87602.0 83987.0 False True 52107.62560011371 63233.21322428235 83532.41938740572 70810.05802207698 70566.62888913896 75587.25588392775 63678.072720852164 98871.3009598249 92232.46287697236 81046.64069365336 0.642933811372569 0.7802077011840177 1.0306709651686652 0.8736951638715114 0.8706915954218559 0.9326389747557652 0.7856966331466801 1.2199308955141848 1.1380170983964664 1.0 16.30646476819114 -7.7594307831752705 24.999999324500617 1.1342305241443258 0.85528879223866 0.5694014029242485 0.10875187076402801 38.31455982458645 476903.7398603621 0.05554967489924888 0.03000381346968895 1.7400800057646294e-08 7.7594307831752705 -0.27894173190566585 SGEHDFGAAFDGDGDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGEHDFGAAFDGDGDR 16 0 A0A3B3ITK7;P36871;P36871-2;P36871-3 A0A3B3ITK7 PGM1 Phosphoglucomutase-1 0 ; 139.21 1.4904000000000002e-05 12236500.0 46980.0 85752.0 109843.0 89434.0 99103.0 75295.0 80720.0 69819.0 67103.0 55751.0 False True 54932.78610270414 94264.89184477534 112462.07370189714 84423.30292894009 79684.47856683808 71346.39765072802 73073.61723780842 67986.32522934531 68084.25442859612 65858.21497532687 0.8341068175516777 1.4313308048220066 1.7076392632875024 1.2818947941508654 1.209939847241397 1.0833333043942541 1.109559639069852 1.0323135125180012 1.0338004826596532 1.0 16.007075789127057 -6.554392340706661 2.0907631343121187 1.05209724380142 1.3493730388425738 0.26873037245264897 0.20268954940068581 0.42997599211573306 3.800507963229677 0.07816585171930705 0.08263200312357524 2.79002220229325e-07 6.554392340706661 0.29727579504115376 SGEHDFGAAFDGDGDR ddPTM_PC-9_Lapatinib_30min_R1 2 SGEHDFGAAFDGDGDR 16 0 A0A3B3ITK7;P36871;P36871-2;P36871-3 A0A3B3ITK7 PGM1 Phosphoglucomutase-1 0 ; 153.94 2.4756999999999997e-05 17523000.0 50341.0 74666.0 110300.0 69486.0 97898.0 103528.0 93257.0 102138.0 98139.0 71438.0 False True 49623.12810859123 74493.11546446518 101231.55977031252 74596.23223850102 92139.8321148733 99100.34877555519 98085.39114999441 106883.70435310104 87085.55237051524 83785.96311484832 0.5922606396559659 0.8890882517200989 1.2082162215113637 0.8903189683008046 1.0997048752494978 1.1827798486927328 1.1706661534169556 1.2756755473060786 1.0393811699836173 1.0 16.354420945182305 -4.893293474185595 2.4605293230133953 1.1155431519958385 0.5361895919103095 0.6903189134561432 0.10730943411631003 0.2313756930674707 2.1334766389100777 0.02885772656060302 0.2596195046826466 1.2785170551967848e-05 4.893293474185595 -0.5793535600855291 SGEISLPIKEEPS(ph)PISK ddPTM_PC-9_AZD4547_30min_R2 2 SGEISLPIKEEPSPISK 17 1 Q9ULH7-4;Q9ULH7;Q9ULH7-5;I3L2A0 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2 1 SGEISLPIKEEPS(0.989)PIS(0.011)K;SGEIS(0.003)LPIKEEPS(0.867)PIS(0.129)K 82.635 0.0020418 41454000.0 176859.0 167152.0 172323.0 235960.0 203804.0 202474.0 138686.0 189028.0 173381.0 191677.0 True False 233096.48310427237 221180.61516448506 170037.88442615213 181563.06754565935 175509.33251311365 189813.26877230752 151028.78532961837 159818.06603131277 182545.56569567314 184966.4465719383 1.2602095538101559 1.1957877726675261 0.9192904311973142 0.9816000194124113 0.9488711913209269 1.0262037914994717 0.8165199047108219 0.8640381485036279 0.9869117836173406 1.0 17.496904060018295 -5.199174181620171 4.098461249294236 0.9375040939966452 1.2445336228401005 0.7765082451997108 0.061369520371484076 0.0992609566951238 3.348825528104307 0.016605090864428337 0.04813393477317159 6.3215826207517365e-06 5.199174181620171 0.30702952884345525 SGEISLPIKEEPS(ph)PISK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGEISLPIKEEPSPISK 17 1 Q9ULH7-4;Q9ULH7;Q9ULH7-5;I3L2A0 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2 1 SGEISLPIKEEPS(0.989)PIS(0.011)K;SGEISLPIKEEPS(0.897)PIS(0.103)K 68.134 0.0084166 10440600.0 47799.0 49331.0 41147.0 55791.0 62798.0 59956.0 69382.0 64668.0 65085.0 47342.0 True False 55890.42662671682 54228.25566277876 42128.10053086646 52665.211146862464 50493.18269921495 56811.801813494196 62809.634677819726 62970.533521409736 66036.74499627702 55924.729840934204 0.9993866181505936 0.9696650447310037 0.7533000275672449 0.9417159688863453 0.9028775434916161 1.0158618910647057 1.1231102028828417 1.1259872636044161 1.180814734091774 1.0 15.77119876153414 -6.997285736296309 2.5409345826939544 1.118546288272332 0.9082428985438921 0.5981458545815463 0.0746222177094839 0.19345040938431501 2.5136448563857807 0.03128777259719123 0.025009909577838 1.006269394037531e-07 6.997285736296309 -0.21030338972843998 SGEISLPIKEEPS(ph)PISK ddPTM_PC-9_Lapatinib_30min_R1 2 SGEISLPIKEEPSPISK 17 1 Q9ULH7-4;Q9ULH7;Q9ULH7-5;I3L2A0 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2 1 SGEISLPIKEEPS(0.971)PIS(0.029)K;SGEISLPIKEEPS(0.958)PIS(0.042)K 81.574 0.0023647 28983000.0 154027.0 134568.0 150354.0 140567.0 173994.0 172809.0 176575.0 160665.0 174026.0 144160.0 True False 151830.54673490732 134256.41606383296 137992.47450322408 150904.76609776585 163760.0150053658 165418.36190745435 185717.18951188942 168130.08243641868 154425.3593049782 169077.86391887427 0.8979918672722147 0.7940508174875626 0.8161474914861394 0.8925163980671763 0.9685479293962452 0.9783561140021512 1.0984122061123207 0.994394408230102 0.9133387170012597 1.0 17.367328265438893 -6.194594721963261 2.0202469389502813 1.0016569174949743 0.8319306881013706 0.678143778817106 0.049163212568007326 0.19208558720821123 1.5406487481584976 0.017215937794901676 0.023509656975681248 6.388593834829411e-07 6.194594721963261 -0.1697262293936037 SGELTALEFS(ph)ASPGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGELTALEFSASPGLR 16 0 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895;Q12774-2 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 SGELTALEFS(0.858)AS(0.141)PGLR;SGELTALEFS(0.5)AS(0.5)PGLR 103.04 0.0014185 5252100.0 21580.3 23068.0 19303.3 19793.3 26298.0 22574.0 24801.0 17547.5 17643.0 17777.3 True False 25233.418559646376 25358.038588899068 19763.563880172922 18684.345571744423 21145.095681772564 21390.17970074417 22451.66973630923 17086.8967181131 17900.995497723245 21000.183764970632 1.2015808452941728 1.2075150804726555 0.9411138541149123 0.8897229558015037 1.0069005070824024 1.0185710725267114 1.06911777475775 0.8136546284235335 0.852420897743905 1.0 14.358114331995697 -5.2607618593708825 24.75915678459131 0.9490168524870743 1.2045479910881556 0.6493080255132259 0.07514077655332074 32.63046484398453 1192368.5012099808 0.021150800546235405 0.049590653642835464 5.4857768903972244e-06 5.2607618593708825 0.25553113860108123 SGELTALEFS(ph)ASPGLR ddPTM_PC-9_Lapatinib_30min_R1 1 SGELTALEFSASPGLR 16 0 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895;Q12774-2 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 SGELTALEFS(0.985)AS(0.015)PGLR 98.421 0.0020529 2332200.0 16733.0 18243.0 19642.0 13979.0 17868.0 20387.0 16624.0 18004.0 16677.0 15952.0 True False 16494.38435154362 18200.75945434659 18027.110580312623 15007.062292576984 16817.03936983961 19515.095534418175 17484.709378143292 18840.53156683338 14798.66064340457 18709.281945296094 0.8816150400518526 0.9728197751021996 0.9635383459943537 0.8021185599990424 0.8988607590077912 1.0430702573983432 0.9345473241178727 1.0070152142621531 0.7909796157155707 1.0 14.191466569136189 SGELTALEFSAS(ph)PGLR ddPTM_PC-9_AZD4547_30min_R2 1 SGELTALEFSASPGLR 16 0 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895;Q12774-2 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 SGELTALEFS(0.38)AS(0.62)PGLR 182.7 7.5361e-07 4349800.0 17758.0 21455.0 19763.0 24685.0 22079.0 24481.0 21435.0 30198.0 19504.0 14545.0 True False 23404.674610654067 28389.90917460772 19500.929707085197 18994.254629448198 19013.711961281584 22950.19919997062 23342.67347490281 25531.59298100593 20534.94162179484 14035.783977153444 1.6675003440314204 2.0226806867944824 1.3893723171308114 1.3532735086523018 1.3546597747750246 1.6351205773277426 1.663082982247271 1.8190357604936522 1.4630420114202605 1.0 13.776822028249434 -8.546731795100321 21.30739701960374 0.9999999897995183 1.6067014418747634 0.4588451900681726 0.20019747620315095 797.6761248782537 712546.9158637387 0.2104915572953859 0.05434868639690031 2.8396721680649374e-09 8.546731795100321 0.6067014520752451 SGELTALEFSAS(ph)PGLR ddPTM_PC-9_Lapatinib_30min_R1 1 SGELTALEFSASPGLR 16 0 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895;Q12774-2 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 SGELTALEFS(0.413)AS(0.587)PGLR 84.195 0.005031100000000001 3214800.0 16546.0 15373.0 21629.0 18707.0 15927.0 18577.0 16687.0 16508.0 17503.0 16590.0 True False 16310.05100583522 15337.404763014307 19850.74711035443 20082.77518472263 14990.205173686787 17782.505015102102 17550.97120988193 17275.02194541688 15531.627825238957 19457.559395214532 0.8382372462317436 0.7882491555845615 1.0202074529057636 1.0321322822050265 0.7704052121446195 0.9139124107967828 0.9020129839201972 0.8878308730572636 0.798231037601708 1.0 14.248043140581219 -6.269103348611657 24.992708384530662 0.8760467012053196 0.9174953593405479 0.04640797988058776 0.09027988823466247 2250.370970220624 7338595.569444181 0.02905957111637093 0.03359279233852456 5.381417062488634e-07 6.269103348611657 0.041448658135228356 SGELTALEFSAS(ph)PGLRR ddPTM_PC-9_AZD4547_30min_R2 3 SGELTALEFSASPGLRR 17 1 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895;Q12774-2 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 SGELTALEFS(0.01)AS(0.99)PGLRR;SGELTALEFS(0.02)AS(0.98)PGLRR;SGELTALEFS(0.07)AS(0.93)PGLRR 90.755 0.0010689999999999999 11457100.0 38521.9 42165.8 60587.0 79445.0 68460.0 66233.0 53555.6 61741.0 42340.8 57680.0 True False 50771.062894704046 55795.0702528396 59783.57679315742 61130.182663014464 58955.510705617904 62091.4400396901 58321.94464905546 52200.34711703709 44578.84824754363 55660.64075642558 0.9121537626000636 1.002415162574256 1.0740727375880215 1.0982658811012245 1.0591956884508549 1.1155358471600443 1.0478130301136115 0.937832306772555 0.8009043309907883 1.0 15.76436989638995 -7.851770214831563 4.056159941935584 0.8921123698731384 1.0493717328038243 0.4282053834484125 0.06982869392046771 0.19578342392674383 5.9447037542848165 0.0419581467968471 0.019112792972813326 1.4067916605830567e-08 7.851770214831563 0.157259362930686 SGELTALEFSAS(ph)PGLRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SGELTALEFSASPGLRR 17 1 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895;Q12774-2 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 SGELTALEFS(0.004)AS(0.996)PGLRR;SGELTALEFS(0.251)AS(0.748)PGLRR;SGELTALEFS(0.163)AS(0.837)PGLRR 140.8 4.2481e-05 12816700.0 43775.0 35517.9 44955.0 60533.0 61808.0 59617.0 57039.0 50839.0 59896.0 43414.0 True False 51185.24290433962 39043.882382376374 46026.8976927869 57141.53226063386 49697.166092440464 56490.57957026956 51635.8529934012 49504.53011837305 60771.8656879007 51284.61453496511 0.9980623500531969 0.761317653187328 0.8974796458966543 1.1142041873333295 0.9690463025427958 1.101511244308078 1.0068488076125952 0.9652900887969348 1.1849921509396804 1.0 15.646238459509025 -5.6549653000011775 6.321790630788242 1.0441209641260054 0.8682719233281563 0.4363426077839365 0.0846949527555841 0.1766498069306963 9.248869426016839 0.0216889288191175 0.03782923262892919 2.2132715422733858e-06 5.6549653000011775 -0.17584904079784913 SGELTALEFSAS(ph)PGLRR ddPTM_PC-9_Lapatinib_30min_R1 3 SGELTALEFSASPGLRR 17 1 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895;Q12774-2 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 SGELTALEFS(0.059)AS(0.941)PGLRR;SGELTALEFS(0.008)AS(0.992)PGLRR;SGELTALEFS(0.012)AS(0.988)PGLRR 128.72 1.4529000000000001e-05 12086600.0 50957.0 40124.0 50555.0 42433.0 48084.0 47135.0 35584.0 35941.2 53052.0 34093.1 True False 50230.34383563065 40031.09534321122 46398.56304794341 45553.66437233842 45255.79365678129 45119.14592705161 37426.365406150784 37611.15936180139 47076.72509767338 39986.04690879981 1.2561967916007308 1.001126603850442 1.1603688445064166 1.1392390069525309 1.1317896405213728 1.1283722552009048 0.9359856324760697 0.9406070934589991 1.177328811848943 1.0 15.287209040368136 -7.232415501325531 21.408455903027747 1.0085310385630852 1.1310821027538682 0.3328485735964265 0.08480340686078332 139.4614184240768 102868.42216770232 0.03131113408578381 0.024243017290129322 5.8557765838200315e-08 7.232415501325531 0.12255106419078299 SGEQAEGS(ph)PGGPGDSQGR ddPTM_PC-9_AZD4547_30min_R2 1 SGEQAEGSPGGPGDSQGR 18 0 P38936 P38936 CDKN1A Cyclin-dependent kinase inhibitor 1 1 S(0.001)GEQAEGS(0.991)PGGPGDS(0.008)QGR 96.633 0.00082244 6857200.0 3456.5 3438.6 4097.9 5286.8 6213.1 3563.3 3695.5 5922.0 4393.1 4172.8 True False 4555.595100333696 4550.060204512054 4043.559168479705 4068.0099402457695 5350.518310912573 3340.4862877029273 4024.3923408678943 5006.890974022022 4625.310297308596 4026.711542101471 1.1313437907589003 1.1299692458569943 1.0041839665449295 1.0102561104048555 1.3287562952970378 0.8295817201645354 0.9994240458475041 1.2434193315493896 1.148656974543234 1.0 11.97538641160548 -7.746718294818236 24.99908716914892 1.147028668833421 1.0616651218799424 0.04945190062478011 0.13245873586064985 636.8101359038503 1081423.2817548008 0.06284398219502862 0.03608425153084732 1.7917677075724525e-08 7.746718294818236 -0.08536354695347859 SGEQAEGS(ph)PGGPGDSQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGEQAEGSPGGPGDSQGR 18 0 P38936 P38936 CDKN1A Cyclin-dependent kinase inhibitor 1 1 SGEQAEGS(1)PGGPGDSQGR;SGEQAEGS(0.772)PGGPGDS(0.228)QGR 173.19 2.9854e-08 10475700.0 5163.200000000001 7872.9 6871.3 7946.5 8916.099999999999 9640.4 7760.4 7508.8 6005.700000000001 6215.3 True False 6037.227782151603 8654.469481816526 7035.137851550362 7501.2833679006 7169.054209759388 9134.840453045721 7025.2787315694595 7311.701956231237 6093.522000831861 7342.084689712272 0.8222770558082727 1.1787482503359255 0.9581935034620339 1.0216830348485897 0.976433058556879 1.2441753043036208 0.956850680490417 0.9958618383245283 0.8299443902315787 1.0 12.841974040440222 -7.82316852845421 2.590265997047003 0.9200755652438434 1.0350785089610357 0.10472098871739888 0.11844573363365776 0.5665165881755485 7.527670341384519 0.075489924699073 0.031588687969079314 1.5025587833466632e-08 7.82316852845421 0.11500294371719233 SGEQAEGS(ph)PGGPGDSQGR ddPTM_PC-9_Lapatinib_30min_R1 2 SGEQAEGSPGGPGDSQGR 18 0 P38936 P38936 CDKN1A Cyclin-dependent kinase inhibitor 1 1 SGEQAEGS(1)PGGPGDSQGR;S(0.004)GEQAEGS(0.995)PGGPGDS(0.001)QGR 208.89 2.0725e-20 10921000.0 16740.2 15235.8 16774.0 14548.2 15799.8 14056.0 14234.699999999999 14878.4 16758.4 12784.3 True False 16501.481678223292 15200.52244118477 15394.906469512476 15618.123159372508 14870.486827601966 13454.857646136354 14971.703115077973 15569.70478026959 14870.892518224577 14994.049220991032 1.1005353814046388 1.0137703442979689 1.0267344226108222 1.0416214412253495 0.9917592378437652 0.8973465037916593 0.9985096683635148 1.0383922682121562 0.9917862946191986 1.0 13.872102422753112 -1.5228787565079875 0.6601106431308721 0.990373609239837 10.842586886666759 0.4099758421688643 0.03753967569311874 259.88204431904796 1.6142333524667132 0.017022340922479017 3749.994194316061 0.029999999224421425 1.5228787565079875 9.852213277426921 SGEQAEGSPGGPGDS(ph)QGR ddPTM_PC-9_AZD4547_30min_R2 1 SGEQAEGSPGGPGDSQGR 18 0 P38936 P38936 CDKN1A Cyclin-dependent kinase inhibitor 1 1 SGEQAEGS(0.002)PGGPGDS(0.998)QGR 148.97 0.00010103 5308800.0 5240.0 5746.6 5652.1 6895.8 10871.0 6205.5 6499.7 7004.9 8157.8 7876.2 True False 6906.2110012291505 7604.076069112122 5577.149460983467 5306.079849047962 9361.749297119079 5817.469104016085 7078.1607084126745 5922.453661588464 8589.004653521222 7600.456635328699 0.9086573784432198 1.0004762126747226 0.7337913665686313 0.6981264552427103 1.2317351109673436 0.7654104724412384 0.9312809806073663 0.7792234000861888 1.1300642929264961 1.0 12.891870382920139 -8.269108001000948 24.928807941398247 1.0650321516808192 0.8835641570905127 0.19179364954889722 0.1509710907350116 1043.9076946184503 3393440.453296748 0.13347820244254463 0.03703546747301015 5.381359414247517e-09 8.269108001000948 -0.1814679945903065 SGESPTHFK ddPTM_PC-9_AZD4547_30min_R2 1 SGESPTHFK 9 0 G3V2F4;E7EPD8;Q9NUW8-2;Q9NUW8 G3V2F4 TDP1 Tyrosyl-DNA phosphodiesterase 1 0 83.005 0.012546 5995900.0 143000.0 112210.0 46642.0 98921.0 71628.0 67655.0 70415.0 40140.0 36700.0 56050.0 False True 188471.02541522327 148479.68811385368 46023.49660465856 76116.29176421493 61683.688589278456 63424.52215489617 76681.79858806993 33937.28532543801 38639.88707546503 54087.706560292216 3.4845445924968614 2.7451651688788394 0.8509049381370167 1.4072752683526557 1.1404382347127051 1.172623617978627 1.4177306353818462 0.6274491466486513 0.7143931501771605 1.0 15.723013104841916 -5.129980236332158 3.288683732325475 1.0592507547449812 3.386566442842741 0.9107262948605637 0.26339419189401636 0.06936615041026313 1.3593839795048728 0.07363660690611505 0.25596984703918224 7.413439772643204e-06 5.129980236332158 2.3273156880977597 up SGETSVRFT(ph)AGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGETSVRFTAGR 12 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 SGETSVRFT(0.999)AGR;SGET(0.008)S(0.008)VRFT(0.984)AGR 111.06 0.011521 23411000.0 13902.4 11430.2 8994.1 22536.3 25142.4 9927.599999999999 18896.8 10018.599999999999 23452.7 10003.8 True False 16255.801735083749 12564.914716439846 9208.553454314193 21273.66417467039 20215.92720622856 9406.979179459013 17106.75830301554 9755.622365584148 23795.65136935067 11817.409749962773 1.3755807811551053 1.0632545525875015 0.7792361988923335 1.800196881109027 1.7106902133347999 0.7960271648775356 1.447589502688559 0.8255296695297275 2.0136097395984454 1.0 13.528626226367583 -5.740943161145496 24.999428600295975 1.3566988101376862 1.0717471833123147 0.1000510608969103 0.40785674696589946 620.3578565075015 756650.4184393721 0.1087540147137222 0.18809185669335698 1.8157532862933133e-06 5.740943161145496 -0.28495162682537156 SGEVAEGEARS(ph)PSHK ddPTM_PC-9_AZD4547_30min_R2 1 SGEVAEGEARSPSHK 15 1 O00257 O00257 CBX4 E3 SUMO-protein ligase CBX4 1 SGEVAEGEARS(0.794)PS(0.206)HK 55.196000000000005 0.03007 4562200.0 19064.0 18210.0 28382.0 40841.0 32976.0 25634.0 19975.0 27670.0 19401.0 27041.0 True False 25125.955444166517 24096.02638404132 28005.636135530654 31425.738437159984 28397.851607193326 24031.101927700944 21752.736303297574 23394.237293345046 20426.497252073506 26094.302820639812 0.9628904675810169 0.9234209685411516 1.0732471500782552 1.2043141621052686 1.0882778437265423 0.9209328983755436 0.83362013742294 0.8965266270628586 0.7827952864836365 1.0 14.6714472365513 -6.8942336717247175 4.600016204882482 0.8705375512081884 1.0525785683562598 0.47077689913077325 0.0873288935755539 0.200857250187186 7.260406238777179 0.034225265766875866 0.030060132458629003 1.2757522068777392e-07 6.8942336717247175 0.18204101714807142 SGEVAEGEARS(ph)PSHK ddPTM_PC-9_Lapatinib_30min_R1 1 SGEVAEGEARSPSHK 15 1 O00257 O00257 CBX4 E3 SUMO-protein ligase CBX4 1 SGEVAEGEARS(0.5)PS(0.5)HK 56.138999999999996 0.028519 3013200.0 29086.0 21291.0 27424.0 25857.0 26792.0 25834.0 24232.0 24372.0 27866.0 19827.0 True False 28671.228306280846 21241.70199761514 25169.304579701336 27758.61003642342 25216.14723509867 24729.14004199536 25486.614391913394 25504.412094360316 24727.437638011128 23254.070532183145 1.23295524826935 0.9134616654842028 1.0823612384278076 1.1937097205414462 1.0843756236225417 1.0634327442918328 1.09600658330508 1.0967719418870234 1.0633595354322536 1.0 14.505195655881188 -8.646064404344823 2.8466483375153295 1.0000430287616204 1.0906465609426617 0.11611115083899837 0.07949940292143057 1.1758241435526497 19.922432829434236 0.07423055279145123 0.01983566077160032 2.259100728683075e-09 8.646064404344823 0.09060353218104122 SGFGEIS(ph)SPVIR ddPTM_PC-9_Lapatinib_30min_R1 2 SGFGEISSPVIR 12 0 G3V1T4;P57740 G3V1T4 NUP107 Nuclear pore complex protein Nup107 1 SGFGEIS(0.579)S(0.421)PVIR;SGFGEIS(0.86)S(0.14)PVIR 155.47 0.00032067 31770000.0 135596.0 122008.0 134254.0 105437.0 117256.0 132241.0 122127.0 105818.0 125222.0 101281.0 True False 133662.3761747393 121725.4979721489 123216.15435542684 113191.18870752107 110359.23261416572 126585.36069882731 128450.13848799952 110734.69058760119 111118.17971388194 118787.28590155058 1.125224599251447 1.0247350720095876 1.037284027665611 0.9528897629779378 0.9290491972821913 1.0656473858973399 1.0813458487001495 0.9322099562016823 0.9354383246534927 1.0 16.858020903602657 -4.345409086011951 1.1963311779194066 0.98965978152308 1.3431518335769044 0.3783902186933785 0.052253008245864783 4.52399017807415 2.7252212384015464 0.01707242733726314 2.561255393440262 4.5143051664781006e-05 4.345409086011951 0.3534920520538244 SGFGEISS(ph)PVIR ddPTM_PC-9_AZD4547_30min_R2 4 SGFGEISSPVIR 12 0 G3V1T4;P57740 G3V1T4 NUP107 Nuclear pore complex protein Nup107 1 SGFGEIS(0.257)S(0.743)PVIR;SGFGEIS(0.094)S(0.906)PVIR;SGFGEIS(0.046)S(0.954)PVIR;SGFGEIS(0.165)S(0.835)PVIR 147.58 6.3216e-05 79138000.0 158866.0 152239.0 197555.0 282011.0 222124.0 192847.0 152653.0 230109.0 160199.0 193442.0 True False 209382.0833819219 201447.27955409468 194935.29161985603 216997.72097651692 191285.91673933214 180788.2466041722 166238.8212719543 194550.94142877965 168666.79208725956 186669.65445916276 1.1216717788896313 1.079164581612084 1.0442794903362373 1.1624691844275576 1.0247295806784669 0.968492962222324 0.8905508597720255 1.0422205044116641 0.9035576380956892 1.0 17.510127892522974 -6.557281792166869 3.632842805218891 0.9598489512272053 1.0965565623476663 0.6384433939599292 0.049755779503761824 0.14687829515830228 4.119601824008835 0.0162195849546614 0.01679265602001192 2.7715212183412393e-07 6.557281792166869 0.13670761112046104 SGFGEISS(ph)PVIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SGFGEISSPVIR 12 0 G3V1T4;P57740 G3V1T4 NUP107 Nuclear pore complex protein Nup107 1 SGFGEIS(0.19)S(0.81)PVIR;S(0.001)GFGEIS(0.146)S(0.854)PVIR;SGFGEIS(0.187)S(0.813)PVIR;SGFGEIS(0.205)S(0.795)PVIR;SGFGEIS(0.099)S(0.901)PVIR;SGFGEIS(0.104)S(0.896)PVIR 182.71 7.4667e-05 56628900.0 295995.0 286721.0 312063.0 317969.0 361769.0 329954.0 332841.0 269646.0 283481.0 220986.2 True False 346101.10733226687 315184.7660069247 319503.7654255178 300154.2277994076 290882.9614304955 312650.63138917985 301311.89091983787 262568.07821355265 287626.3733316372 261049.24873420337 1.3258077125694474 1.207376644580354 1.223921413199821 1.1497992400086177 1.1142838481280917 1.1976691482744555 1.154233894105665 1.00581817219055 1.1018088530279366 1.0 17.993962481239876 -1.5228787493626323 0.14580819777170123 0.9657544148450943 2.148563846694778 0.7647294092834033 0.045708924124723695 35.3616920855725 0.34153712040698364 0.18083979944404452 8.787679975040364 0.029999999718005068 1.5228787493626323 1.1828094318496838 SGFGEISS(ph)PVIR ddPTM_PC-9_Lapatinib_30min_R1 1 SGFGEISSPVIR 12 0 G3V1T4;P57740 G3V1T4 NUP107 Nuclear pore complex protein Nup107 1 SGFGEIS(0.085)S(0.915)PVIR 155.47 0.00032067 22541000.0 77833.0 67338.0 75727.0 68087.0 70647.0 71289.0 67082.0 58474.0 70595.0 49764.0 True False 76723.08714717581 67182.08299823449 69501.01837467325 73094.34511157377 66491.68235734596 68240.13565277573 70555.17772525313 61190.915509832004 62643.847701693754 58365.6410936381 1.314524876443766 1.1510553424822636 1.1907865153604715 1.2523523042316262 1.1392264543221748 1.1691833478415088 1.2088478153107052 1.0484064659147874 1.0733000876524592 1.0 15.832831707365111 -7.932348922838669 0.6645214973310742 0.995183489131904 1.2176064238715907 0.6688708200430273 0.05199140221289059 0.41665947788611046 0.3834357347668938 0.04861103837296797 0.02349361204009159 1.1685601638744875e-08 7.932348922838669 0.22242293473968666 SGGDFKPTS(ph)PSLPASK ddPTM_PC-9_AZD4547_30min_R2 1 SGGDFKPTSPSLPASK 16 1 Q5T5P2;Q5T5P2-2;Q5T5P2-7;Q5T5P2-10;Q5T5P2-9 Q5T5P2;Q5T5P2-9 KIAA1217 Sickle tail protein homolog 1 SGGDFKPT(0.265)S(0.641)PS(0.06)LPAS(0.034)K 59.857 0.022563999999999997 14217000.0 63819.0 62743.0 87897.0 95235.0 100320.0 87740.0 91273.0 108270.0 107720.0 97580.0 True False 84112.11448233665 83023.44774376201 86731.4283491205 73280.0421160826 86392.2996492489 82253.6039297995 99396.1201807701 91539.35929708958 113413.85928526145 94163.75390104023 0.8932536246455598 0.8816922043168974 0.9210702075479 0.7782192094114577 0.9174687294225908 0.8735166188918351 1.055566670432752 0.9721294606977043 1.2044322213879854 1.0 16.522884215075152 -7.347236383010657 1.7605865908504448 1.0736334547465805 0.8725957567994649 0.6135874195302302 0.0692232214925763 0.23746318622791596 1.4327108204790628 0.03707195375717769 0.021334793667189912 4.495351099304533e-08 7.347236383010657 -0.20103769794711557 SGGGGGGGGSSWGGR ddPTM_PC-9_Lapatinib_30min_R1 2 SGGGGGGGGSSWGGR 15 0 Q13151 Q13151 HNRNPA0 Heterogeneous nuclear ribonucleoprotein A0 0 ; 113.99 0.00084211 5941500.0 9279.599999999999 6645.4 6849.5 7680.9 8188.2 7486.4 7685.2 5966.9 6957.1 7573.5 False True 9147.27120232978 6630.012984592156 6286.360549834605 8245.779008731271 7706.586174620584 7166.224123650771 8083.102052027596 6244.143957239401 6173.5181364891705 8882.569383945585 1.0298001408086515 0.74640711465483 0.707718710443919 0.9283101152730365 0.8676077654456061 0.8067737851395849 0.90999593728331 0.7029659648395326 0.6950149072460079 1.0 13.116761337510255 -7.757065967341994 24.999800475332304 0.7742428336848189 0.8479483847364636 0.0315225725235887 0.11737059846609375 306.1483763832966 1750073.1454083803 0.05600068423113676 0.030901028924024306 1.7495809151153283e-08 7.757065967341994 0.07370555105164467 SGGGLHSVAEGVRLS(ph)PEPGR ddPTM_PC-9_AZD4547_30min_R2 2 SGGGLHSVAEGVRLSPEPGR 20 1 Q9NWK9-2;Q9NWK9 Q9NWK9-2 ZNHIT6 Box C/D snoRNA protein 1 1 S(0.001)GGGLHS(0.002)VAEGVRLS(0.998)PEPGR;S(0.001)GGGLHS(0.02)VAEGVRLS(0.979)PEPGR 47.754 0.028349 28730000.0 58509.0 47239.0 126801.0 171504.0 148608.0 132523.0 75911.0 158061.0 90992.0 121002.0 True False 77113.64493719782 62508.082941006476 125119.53588969853 131966.40251038637 127976.34436080154 124236.31586036933 82666.93194090704 133636.30433044521 95801.65135615031 116765.75681014216 0.6604131814311146 0.5353288896387908 1.0715430560103283 1.1301806806678778 1.09600920558317 1.0639790230827184 0.7079723901873145 1.1444819781173867 0.8204601586398408 1.0 16.833257720200393 -5.261422694510423 24.999999999756813 1.0088036757921734 0.5978710079019104 0.592617105491769 0.13475891428641362 0.9384713787557835 1402870.3635374801 0.0349090403413897 0.0811225196430316 5.477435919959697e-06 5.261422694510423 -0.41093266789026306 SGGGLHSVAEGVRLS(ph)PEPGR ddPTM_PC-9_Lapatinib_30min_R1 2 SGGGLHSVAEGVRLSPEPGR 20 1 Q9NWK9-2;Q9NWK9 Q9NWK9-2 ZNHIT6 Box C/D snoRNA protein 1 1 S(0.003)GGGLHS(0.022)VAEGVRLS(0.975)PEPGR;S(0.002)GGGLHS(0.057)VAEGVRLS(0.94)PEPGR 44.106 0.038706 24751000.0 91851.0 55339.0 127745.0 93112.0 115971.0 135640.0 87064.0 89587.0 125859.0 82317.0 True False 90541.18789658956 55210.865945517995 117242.29920996034 99959.76709252648 109149.8137877584 129838.99339228327 91571.74791257628 93749.53907342286 111683.43406597438 96545.38376949217 0.937809601676679 0.571864379112493 1.2143749875176144 1.0353655782361004 1.1305544555953089 1.3448493166931894 0.9484839599499574 0.9710411354027598 1.15679724607678 1.0 16.55891965921139 -5.268547512045814 24.97746845103443 1.1012390915591603 0.7548369848864823 0.49085435142761624 0.1406854988621244 392.10806218465177 1377843.1313332077 0.03622423354894294 0.07800335798728364 5.388308937641659e-06 5.268547512045814 -0.346402106672678 SGGGPGPSGSET(ph)PPPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGGGPGPSGSETPPPPR 17 0 P27987-2;P27987 P27987-2 ITPKB Inositol-trisphosphate 3-kinase B 1 SGGGPGPS(0.012)GS(0.012)ET(0.976)PPPPR;SGGGPGPSGS(0.001)ET(0.999)PPPPR 160.03 1.457e-17 2423000.0 12187.599999999999 15655.1 54223.0 28294.0 47076.0 44715.0 24591.0 27662.0 38822.0 18204.5 True False 14250.719963927566 17209.234867048453 55515.88196187262 26708.778910385656 37851.79573789362 42370.06668374128 22261.562456577583 26935.901810311698 39389.6983059917 21504.8317432573 0.6626752598701818 0.8002496867916346 2.581553886339021 1.2419896714030334 1.7601530758203587 1.9702579954863464 1.0351888692901563 1.2525511537079232 1.8316673562601615 1.0 14.392373223032992 -5.03533877822005 24.991747485271414 1.5887344452076384 0.6970678900793605 0.35731463963661814 0.4590322817140533 516.6077584601533 365347.85514334356 0.1132626512930131 0.29995711431841393 9.218520414682421e-06 5.03533877822005 -0.8916665551282779 SGGGPGPSGSET(ph)PPPPR ddPTM_PC-9_Lapatinib_30min_R1 2 SGGGPGPSGSETPPPPR 17 0 P27987-2;P27987 P27987-2 ITPKB Inositol-trisphosphate 3-kinase B 1 SGGGPGPS(0.021)GS(0.1)ET(0.879)PPPPR;SGGGPGPS(0.002)GS(0.011)ET(0.987)PPPPR 104.09 0.0019836 7508100.0 25006.0 18208.0 83936.0 25918.0 50826.0 53612.0 29797.0 27016.0 81192.0 23700.0 True False 24649.40985446122 18165.840494696182 77035.10608232986 27824.096179913446 47836.514607760655 51319.13973567602 31339.74286215928 28271.261986756876 72047.30197033654 27796.51342173504 0.8867806361349985 0.6535294631769067 2.7713945599412297 1.0009923099980171 1.7209537715027114 1.846243770110673 1.127470283292928 1.0170794285534608 2.5919546411169794 1.0 14.762616313410977 SGGGPGPSGSET(ph)PPPPRR ddPTM_PC-9_AZD4547_30min_R2 1 SGGGPGPSGSETPPPPRR 18 1 P27987-2;P27987 P27987-2 ITPKB Inositol-trisphosphate 3-kinase B 1 SGGGPGPS(0.005)GS(0.086)ET(0.909)PPPPRR 80.382 0.0030575 4037500.0 5488.1 4626.3 7303.2 12004.0 7281.8 9062.1 7509.8 8197.0 5540.7 8448.7 True False 7233.2016404285705 6121.661002772669 7206.354796173891 9236.66325995124 6270.847763017356 8495.44545443625 8178.1576515896895 6930.341998321265 5833.5700904367595 8152.913584584138 0.8871922369084597 0.7508556222584961 0.8838993227893353 1.1329278992256584 0.7691542045624684 1.0420134306954738 1.0030963246137288 0.8500448246410264 0.7155196764831546 1.0 12.993100008160395 -5.517362666505128 24.849295342597305 0.9315155688720841 0.8186122900984849 0.11509830867202042 0.12310065866667022 449.74066311758895 2026026.620649024 0.03327502120230591 0.0600033310617988 3.038346732307058e-06 5.517362666505128 -0.11290327877359918 SGGGPGPSGSET(ph)PPPPRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SGGGPGPSGSETPPPPRR 18 1 P27987-2;P27987 P27987-2 ITPKB Inositol-trisphosphate 3-kinase B 1 S(0.008)GGGPGPS(0.097)GS(0.013)ET(0.881)PPPPRR;SGGGPGPS(0.002)GS(0.017)ET(0.981)PPPPRR;SGGGPGPS(0.001)GS(0.027)ET(0.972)PPPPRR;S(0.003)GGGPGPS(0.006)GS(0.072)ET(0.919)PPPPRR 95.307 0.00076768 11282200.0 23546.0 30103.100000000002 45843.5 39723.4 48945.0 50996.5 40130.600000000006 39158.2 36641.200000000004 31640.199999999997 True False 27531.872745301658 33091.53682354291 46936.58290244192 37497.826683000436 39354.57860462235 48322.15376579253 36329.1390476163 38130.33874154242 37177.00823165998 37376.31779631462 0.7366127636044542 0.885361072855759 1.2557840276890508 1.0032509592664527 1.0529281888892434 1.2928548507407327 0.9719828273505964 1.020173762148987 0.9946674906356266 1.0 15.18983682560781 -5.029953742670084 5.904351311186852 1.0759871665276581 0.7678829748928042 0.5168190554955624 0.10614377012717163 0.11851687324451823 13.502708129711552 0.0270013550131282 0.08224518925743517 9.333537083488002e-06 5.029953742670084 -0.3081041916348539 SGGGPGPSGSET(ph)PPPPRR ddPTM_PC-9_Lapatinib_30min_R1 1 SGGGPGPSGSETPPPPRR 18 1 P27987-2;P27987 P27987-2 ITPKB Inositol-trisphosphate 3-kinase B 1 S(0.002)GGGPGPS(0.002)GS(0.021)ET(0.975)PPPPRR 83.065 0.0020276 1847900.0 8512.2 4213.1 5077.8 6067.9 6008.7 4104.2 6266.3 6086.6 5945.3 3540.0 True False 8390.814467053702 4203.3448258020935 4660.322884874834 6514.153607921009 5655.2800795587245 3928.6729333574845 6590.738352758618 6369.405656225735 5275.677707215515 4151.884283246502 2.020965396581967 1.0123945030845978 1.1224597235717675 1.5689631896068568 1.3620996380796686 0.9462385426323875 1.5874089697907217 1.534099994531947 1.2706706996877766 1.0 12.019550519708353 -4.747400886690403 24.96909951539423 1.291696134302548 2.020967264223077 0.4839477011924711 0.23228422285688602 668.9203841673952 1189684.0879152177 0.05884480698898941 1.201691957158999 1.7889537518771783e-05 4.747400886690403 0.729271129920529 SGGGYGGDRS(ph)SGGGYSGDR ddPTM_PC-9_AZD4547_30min_R2 1 SGGGYGGDRSSGGGYSGDR 19 1 Q92804-2;Q92804;A0A075B7F4 Q92804-2 TAF15 TATA-binding protein-associated factor 2N 1 S(0.001)GGGY(0.002)GGDRS(0.494)S(0.494)GGGY(0.003)S(0.005)GDR 54.763999999999996 0.015303 6617400.0 9415.4 11050.0 12670.0 23566.0 20538.0 15567.0 13637.0 17667.0 12989.0 15944.0 True False 12409.30134751393 14621.696405472632 12501.987521569059 18133.222791070544 17686.653211685378 14593.59302912229 14850.666581630494 14936.971097272388 13675.572022430939 15385.805412975895 0.806542200062424 0.9503367560557578 0.812566335398034 1.1785683169876544 1.1495435394476665 0.9485101778821746 0.9652186663628228 0.9708280259852387 0.8888434277803487 1.0 13.909312347100823 -5.727652446966453 24.99999917263764 1.0141100886678025 0.8658672109781826 0.38499349233211133 0.09129199731757556 226.0077271750217 167228.5310576088 0.02672106090745824 0.04627907236400262 1.8721797911571734e-06 5.727652446966453 -0.14824287768961986 SGGIVIS(ph)PFR ddPTM_PC-9_AZD4547_30min_R2 3 SGGIVISPFR 10 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 SGGIVIS(1)PFR;SGGIVIS(1)PFR;SGGIVIS(1)PFR 89.266 0.009459 43424800.0 65604.0 85760.0 98028.0 86561.0 87081.1 116602.0 101269.0 117484.0 87839.0 96873.0 True False 86464.70735203024 113480.24287179484 96728.08466964254 66605.69880411858 74991.39239420088 109310.85850720847 110281.74481595185 99329.54731374598 92481.99021312728 93481.50575584629 0.9249391807814646 1.2139325522652682 1.034729638633289 0.7125013473582511 0.802205653277156 1.1693313840355233 1.1797172491421373 1.0625582730040048 0.9893078793004305 1.0 16.51239335210618 -6.778185002738979 24.997051890644432 1.090313727760764 0.9458937714583662 0.2092668777962523 0.1373535479000837 449.55966165353976 671076.5604099133 0.05420579857617278 0.0479327295605238 1.666537142249484e-07 6.778185002738979 -0.1444199563023978 SGGIVIS(ph)PFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SGGIVISPFR 10 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 SGGIVIS(1)PFR;SGGIVIS(1)PFR;SGGIVIS(1)PFR 96.334 0.005571 51888000.0 95237.0 134051.0 107062.0 105307.0 129018.0 92070.0 107986.0 81649.0 87469.0 83609.0 True False 111358.74308350861 147358.69736780412 109614.7641148959 99406.99019990036 103737.84906346236 87241.6871200283 97756.78432906282 79505.80026426638 88748.06864990946 98766.64985151996 1.12749337201291 1.4919884150098703 1.1098358026690625 1.0064833660890904 1.0503327714305974 0.8833111910870965 0.9897752376538507 0.8049863023985401 0.898563116024773 1.0 16.59173635439422 -5.641368212038102 2.167387832023247 0.9342733561004789 1.3121540728496748 0.6370118674239059 0.1080830012374612 0.17916704845582074 1.6963830403173126 0.03099082670668717 0.06691738996738204 2.283661803563066e-06 5.641368212038102 0.3778807167491959 SGGIVIS(ph)PFR ddPTM_PC-9_Lapatinib_30min_R1 3 SGGIVISPFR 10 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 SGGIVIS(1)PFR;SGGIVIS(1)PFR;SGGIVIS(1)PFR 116.84 0.0010071 79628600.0 175626.0 212530.0 196460.0 164921.0 240953.0 192974.0 195174.0 210125.0 176139.0 175440.0 True False 173121.54103413614 212037.8998428043 180307.81715753058 177049.840500328 226780.61827182493 184720.9518643651 205279.15472628357 219888.17459902554 156300.37099410183 205764.57024089395 0.8413573864123364 1.030487899809797 0.8762821361638669 0.8604486199594572 1.1021363785141773 0.8977296317247788 0.9976409178993152 1.0686396318938518 0.7596077925909057 1.0 17.650635066298946 -4.733225692940623 24.10060029089053 0.9556811255516299 0.841356408757645 0.10304751393763534 0.10035246339387867 4735.579354115109 4044868.944915527 0.02377879455656147 2.1661755115301435 1.8483078459064284e-05 4.733225692940623 -0.11432471679398493 SGGIVIS(ph)PFRLEELTNR ddPTM_PC-9_AZD4547_30min_R2 2 SGGIVISPFRLEELTNR 17 1 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 SGGIVIS(1)PFRLEELTNR;S(0.002)GGIVIS(0.91)PFRLEELT(0.088)NR 109.42 0.00021669999999999998 291210000.0 130901.0 114670.0 178065.0 267189.0 203637.0 181798.0 129778.0 183147.0 128310.0 171228.0 True False 172524.79509005698 151734.83500593159 175703.74175439586 205592.70407889967 175365.51758048323 170430.14232083055 141327.99058670082 154845.839449377 135092.20464994328 165233.35983774695 1.0441281062097265 0.9183062981647869 1.0633672396841076 1.2442566336530596 1.0613202912092672 1.0314511699585764 0.8553235903783575 0.9371342421495871 0.817584323060421 1.0 17.33414546394078 -7.13820588258867 4.43606842131975 0.8978041343788347 1.066027590171841 0.44786730672116815 0.08637769003910303 0.23047203639237132 7.28467227265913 0.03632471327973538 0.027832177087979068 7.274348734222901e-08 7.13820588258867 0.16822345579300635 SGGIVIS(ph)PFRLEELTNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGGIVISPFRLEELTNR 17 1 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 SGGIVIS(1)PFRLEELTNR;SGGIVIS(0.924)PFRLEELT(0.076)NR 119.96 0.00044353 91486300.0 62668.0 44125.0 55431.0 66212.0 81877.0 77062.0 76317.0 69848.0 73733.0 49610.0 True False 73276.4546505804 48505.438388034156 56752.68526323815 62502.35630220031 65833.7896089623 73020.73306010221 69087.70127276784 68014.56401007358 74811.2056358686 58603.90028745606 1.250368222783031 0.827682767701667 0.9684114023957863 1.066522125585875 1.1233687397262493 1.2460046635450988 1.178892546978751 1.1605808431940123 1.2765567695821374 1.0 15.838709063618838 -6.227054323249547 2.373593704358632 1.1819069202383905 0.9998124869337188 0.24049976202134704 0.1192275857709076 0.35891635849942644 3.9777108361521196 0.03768073738108272 0.04920830902811105 5.928511638035157e-07 6.227054323249547 -0.18209443330467168 SGGIVIS(ph)PFRLEELTNR ddPTM_PC-9_Lapatinib_30min_R1 1 SGGIVISPFRLEELTNR 17 1 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 S(0.001)GGIVIS(0.98)PFRLEELT(0.02)NR 67.846 0.008600499999999999 64006000.0 93991.0 67297.0 85709.0 77932.0 66879.0 71020.0 54330.0 75753.0 81324.0 58240.0 True False 92650.6711041614 67141.17793121535 78662.33686630776 83663.37925353074 62945.30870917293 67982.64015570597 57142.94156126832 79272.7609299228 72164.43474031506 68306.7064000779 1.3563920145922266 0.9829368369478106 1.1516048864305664 1.224819401531492 0.9215099369672015 0.9952557184872324 0.8365641468141868 1.160541403732978 1.0564765678737622 1.0 16.05973960982405 SGGLQT(ph)PECLSR ddPTM_PC-9_AZD4547_30min_R2 1 SGGLQTPECLSR 12 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 SGGLQT(0.981)PECLS(0.019)R 144.88 0.00025135 17280000.0 76506.0 89263.0 110400.0 137230.0 117370.0 105310.0 77618.0 113630.0 97407.0 98984.0 True False 100833.31657634287 118115.51911689619 108936.02386592142 105593.74368236479 101075.20145367198 98724.94905228156 84525.85163400986 96071.09445763651 102555.7351596682 95518.6002883848 1.0556406424708085 1.2365708747855177 1.140469223135886 1.105478339962705 1.058172975195522 1.0335677946935604 0.8849150990363531 1.0057841526946967 1.073672927053341 1.0 16.5434940753251 -6.381462994178846 1.5606887793703004 0.9915594007292541 1.1514529100428268 0.53170851213064 0.06036742232561048 0.2924949910848029 1.4280515767110646 0.023404975748523595 0.028867045811454016 4.154674513213597e-07 6.381462994178846 0.1598935093135727 SGGLQT(ph)PECLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGGLQTPECLSR 12 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 S(0.006)GGLQT(0.99)PECLS(0.005)R;S(0.063)GGLQT(0.936)PECLS(0.001)R 90.49799999999999 0.016909 25118000.0 185507.0 222220.0 206134.0 253053.0 293915.0 230704.0 230609.0 240297.0 222612.0 202585.0 True False 216909.6711697392 244280.53299918302 211049.016327548 238875.2608188958 236324.46563648095 218605.47610881907 208764.04605542248 233989.4583657166 225867.27935947187 239312.05683802275 0.906388395284879 1.0207614953747322 0.8818988024092557 0.9981747847354695 0.9875159185833919 0.9134745611951394 0.872350724045314 0.9777587533924013 0.9438190551023891 1.0 17.86853355790847 -6.768549141742833 24.961851090425636 0.935769928759642 0.9602807376116032 0.022770174444019187 0.05035492221013877 560.1384741887827 1966594.3528868272 0.017165177513418683 0.015459840336786008 1.7039265039354113e-07 6.768549141742833 0.024510808851961108 SGGLQT(ph)PECLSR ddPTM_PC-9_Lapatinib_30min_R1 2 SGGLQTPECLSR 12 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 S(0.022)GGLQT(0.978)PECLSR;S(0.002)GGLQT(0.998)PECLSR 112.02 0.0024529 28045000.0 139400.0 147552.0 172402.0 151120.0 175037.0 177491.0 148788.0 161469.0 185946.0 158051.0 True False 137412.13043717106 147210.35240956768 158227.7730509651 162233.86892154146 164741.66779598236 169900.12368172937 156491.51461472473 168971.4392115654 165002.80338181378 185369.9047602806 0.7412860820901415 0.7941437559669643 0.8535785420809513 0.8751899027587109 0.888718522076307 0.9165464259230393 0.8442120894278861 0.9115365270866292 0.8901272490547727 1.0 17.500047512480975 -1.9278933888193472 0.23857700628578704 0.9464301545332339 8.667629197356941e-113 0.7711845009777429 0.03201953554304083 21.438270576239898 0.33892823341834893 0.04584223173913428 7.709892697998654 0.01180610417880472 1.9278933888193472 -0.9464301545332339 SGGLQTPECLS(ph)R ddPTM_PC-9_AZD4547_30min_R2 4 SGGLQTPECLSR 12 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 SGGLQTPECLS(1)R;SGGLQTPECLS(1)R;SGGLQTPECLS(1)R;SGGLQTPECLS(1)R 168.0 9.284799999999999e-05 209012100.0 180868.0 198311.0 210432.0 211993.0 228603.0 257482.0 246493.0 253696.0 231937.0 203363.0 True False 238380.26171189154 262411.1525670303 207641.5341861738 163121.28910920036 196865.41942501307 241381.60983647927 268430.3994797861 214493.11255411894 244196.71631123 196243.32326888017 1.2147178193944361 1.3371723847516135 1.0580820316708381 0.8312195614711534 1.003170024568329 1.2300118333491197 1.3678447501217648 1.092995720726937 1.2443568129787892 1.0 17.58228404487045 -6.780307806656367 24.6938937626223 1.2041542661713345 1.0866421736820546 0.08764259926585738 0.15339732757461777 523.8764818130777 685613.7859248314 0.05913234711641241 0.052240347311323494 1.6584110902566987e-07 6.780307806656367 -0.11751209248927985 SGGLQTPECLS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SGGLQTPECLSR 12 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 SGGLQTPECLS(1)R;SGGLQTPECLS(1)R;SGGLQTPECLS(1)R;SGGLQTPECLS(1)R;SGGLQTPECLS(1)R 143.58 8.6004e-05 145199300.0 72705.0 89608.0 102836.0 97483.9 122848.0 111334.0 130720.0 97910.0 103367.0 102487.2 True False 85012.5205107942 98503.69004135874 105288.00024770186 92022.19313006809 98776.81627174692 105495.44904769427 118337.25526915617 95339.96624422004 104878.54682384853 121067.31807177133 0.7021921511501307 0.8136274232403796 0.8696649262956734 0.7600911178648175 0.8158834097009557 0.8713784258866153 0.9774500431157093 0.7874954840223721 0.8662828952870193 1.0 16.88544993881463 -6.755851606143133 3.5038083088386336 0.8939067819870817 0.7940404216481945 0.391943842065679 0.06800095975476121 0.29005842316213437 7.534620046618932 0.024470777167842978 0.022901541657092676 1.7544798867591075e-07 6.755851606143133 -0.09986636033888718 SGGLQTPECLS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 4 SGGLQTPECLSR 12 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 SGGLQTPECLS(1)R;SGGLQTPECLS(1)R;SGGLQTPECLS(1)R;SGGLQTPECLS(1)R 159.12 0.0001028 206144700.0 139854.0 187673.0 166845.0 142961.0 211323.0 223072.0 210458.0 227693.0 241669.0 171175.0 True False 137859.6563139174 187238.45469909496 153127.64814032498 153474.82884391598 198893.39661700354 213531.7305662302 221354.48546109747 238272.44801416364 214449.69233261008 200762.3706736492 0.6866807552198924 0.9326371972537716 0.7627308226462558 0.764460134281828 0.9906906157245783 1.0636043490108928 1.1025695936860695 1.1868381869304045 1.068176728602246 1.0 17.61512936160485 -6.468643898871705 2.558621197083804 1.0980170469967416 0.794479462044786 0.7857274228309701 0.07307153565071287 0.126543158734752 1.6423170858968335 0.024851356556402318 0.027528116426342925 3.3990386360253636e-07 6.468643898871705 -0.3035375849519556 SGGS(ph)GGCSGAGGASNCGTGSGR ddPTM_PC-9_AZD4547_30min_R2 1 SGGSGGCSGAGGASNCGTGSGR 22 0 E9PL01;A0A087WUC6;E9PI68;Q15005 E9PL01 SPCS2 Signal peptidase complex subunit 2 1 S(0.072)GGS(0.927)GGCS(0.001)GAGGASNCGTGSGR 137.39 4.5913e-05 2096300.0 717.14 545.84 1108.5 1060.5 1210.3 1019.3 472.69 616.58 2133.1 1125.1 True False 945.1756025613498 722.2721055170294 1093.8005657189665 816.0181095616701 1042.2707362987048 955.5630098660205 514.7584942781342 521.3017285988683 2245.851311190041 1085.7105914537879 0.870559438216165 0.6652528870975578 1.0074513174402637 0.7515981846221154 0.9599894709538421 0.8801268196034662 0.4741212790315165 0.48014796272811067 2.068554298786753 1.0 10.084423872226157 -8.249816724419244 24.999801746330476 1.5342772095970922 0.7668760635484977 0.5241077607332554 0.2946402527134265 483.23335062073744 1039418.464439859 0.19313878885784097 0.07166603056919396 5.62578687595559e-09 8.249816724419244 -0.7674011460485946 SGGS(ph)GGCSGAGGASNCGTGSGR ddPTM_PC-9_Lapatinib_30min_R1 1 SGGSGGCSGAGGASNCGTGSGR 22 0 E9PL01;A0A087WUC6;E9PI68;Q15005 E9PL01 SPCS2 Signal peptidase complex subunit 2 1 S(0.118)GGS(0.781)GGCS(0.101)GAGGASNCGTGSGR 215.32 2.938e-32 1551700.0 2649.7 2848.2 818.36 489.55 853.5 701.68 921.29 673.34 3055.8 0.0 True False 2611.9147921045314 2841.605167892886 751.0775997609528 525.5531400909261 803.2988080455619 671.6707820959705 968.989888293409 704.6258345485221 2711.6236249994427 0.0 0.0 SGGSGHAVAEPAS(ph)PEQELDQNK ddPTM_PC-9_AZD4547_30min_R2 4 SGGSGHAVAEPASPEQELDQNK 22 0 P46013 P46013 MKI67 Antigen KI-67 1 SGGSGHAVAEPAS(1)PEQELDQNK;SGGSGHAVAEPAS(1)PEQELDQNK;SGGSGHAVAEPAS(1)PEQELDQNK;SGGSGHAVAEPAS(1)PEQELDQNK 153.65 9.342200000000001e-07 33462300.0 21796.5 50193.9 195276.0 296874.0 202050.0 168249.0 81219.0 253553.0 107572.0 161465.0 True False 28727.333604635733 66418.09657978764 192686.5126489283 228434.285957578 173998.84513686982 157728.36343269714 88447.33365794847 214372.20991830592 113258.03630740955 155812.15949612102 0.18437157727315182 0.4262703039003906 1.236659021170458 1.466087670540661 1.1167218636822858 1.0122981668617705 0.567653602542813 1.3758374866991223 0.7268883036707359 1.0 17.249448299365497 -5.139801551626187 4.339613868453789 1.0717356254449892 0.23949762364250504 0.5833667394681532 0.2586310051848311 0.15404070609536485 4.638474700408336 0.06852355520710256 0.20442105231008922 7.2476706257588515e-06 5.139801551626187 -0.8322380018024842 SGGSGHAVAEPAS(ph)PEQELDQNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SGGSGHAVAEPASPEQELDQNK 22 0 P46013 P46013 MKI67 Antigen KI-67 1 SGGSGHAVAEPAS(1)PEQELDQNK;SGGSGHAVAEPAS(1)PEQELDQNK;SGGSGHAVAEPAS(1)PEQELDQNK 155.87 1.1280999999999999e-23 8851600.0 11408.3 31156.7 60460.0 64668.0 90972.0 53632.0 72673.0 49951.0 52819.0 25606.300000000003 True False 13339.49986580417 34249.731268543066 61901.595695826836 61044.861616484755 73146.68964796631 50819.44350625995 65788.88733304321 48639.8391774593 53591.37795126927 30248.51949064074 0.44099678564207323 1.1322779377397412 2.046433899516303 2.0181107255637016 2.418190737255712 1.6800638299664254 2.1749456978679267 1.608007267678309 1.7717025115179965 1.0 14.884576911167063 -4.996542375416004 2.7696921354575026 1.89374001255119 0.4281050159260137 0.5918717618660205 0.36830496032491855 0.1898626606637015 2.6421408524127656 0.09263926987313305 0.5095670605388988 1.0079932516390927e-05 4.996542375416004 -1.4656349966251763 SGGSGHAVAEPAS(ph)PEQELDQNK ddPTM_PC-9_Lapatinib_30min_R1 3 SGGSGHAVAEPASPEQELDQNK 22 0 P46013 P46013 MKI67 Antigen KI-67 1 SGGSGHAVAEPAS(1)PEQELDQNK;SGGSGHAVAEPAS(1)PEQELDQNK;SGGSGHAVAEPAS(1)PEQELDQNK 164.31 7.969899999999999e-09 14089800.0 27567.9 34770.9 112513.0 32438.0 59572.0 91136.0 93742.0 100564.0 95379.0 34075.2 True False 27174.776690666302 34690.39011736772 103262.61545273982 34823.598729995865 56068.09208305827 87238.3257283923 98595.50207687129 105236.57056693162 84636.41263460352 39965.05291765004 0.6799634857649574 0.8680181204526108 2.5838228130341157 0.8713512478452513 1.4029280080922033 2.182865262512004 2.4670429507508014 2.6332148435728775 2.1177605546776332 1.0 15.286451379055606 -6.7432074531296795 5.128598983714598 2.211292131271435 1.2997992446327225 0.26899299967434565 0.6422059822494262 0.2282136585525222 16.24173712976798 0.22001266048762513 0.2102082702395755 1.806311083959e-07 6.7432074531296795 -0.9114928866387124 SGGSGHAVAEPAS(ph)PEQELDQNKGK ddPTM_PC-9_AZD4547_30min_R2 4 SGGSGHAVAEPASPEQELDQNKGK 24 1 P46013 P46013 MKI67 Antigen KI-67 1 SGGSGHAVAEPAS(1)PEQELDQNKGK;SGGSGHAVAEPAS(1)PEQELDQNKGK;SGGSGHAVAEPAS(1)PEQELDQNKGK;SGGSGHAVAEPAS(1)PEQELDQNKGK 135.36 6.679600000000001e-07 42420100.0 21062.4 30255.200000000004 158535.0 391317.0 245729.0 160684.0 75646.0 168121.0 89827.0 174069.0 True False 27759.805074864318 40034.60172731724 156432.72231507103 301104.9114373822 211613.7699412907 150636.40407859508 82378.34745428035 142141.76248624732 94575.07183454502 167974.89729247987 0.16526162850707757 0.2383368132537597 0.9312863102555647 1.792558985245842 1.2597940129877043 0.8967792599170649 0.49042058534997757 0.8462083607573124 0.5630309847421414 1.0 17.357886122574172 -5.262706670707328 5.412147600438168 0.9889003016318946 0.19093096126020484 0.4466261904442077 0.3435052888800796 0.15833844166203961 17.125652020387925 0.10134578026037949 0.24575506618078022 5.461265990070526e-06 5.262706670707328 -0.7979693403716898 SGIET(ph)FSPPPPPPK ddPTM_PC-9_AZD4547_30min_R2 2 SGIETFSPPPPPPK 14 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 S(0.001)GIET(0.887)FS(0.112)PPPPPPK;SGIET(0.5)FS(0.5)PPPPPPK 99.844 0.0051464 13257300.0 109694.0 107803.0 154525.0 209561.0 170766.0 153197.0 131904.0 186372.0 143115.0 152650.0 True False 144574.41022305918 142648.21154743573 152475.89753515858 161249.94913517492 147058.08853572237 143617.56737216207 143643.2004680932 157572.48980250437 150679.76672493696 147305.76996304403 0.9814578903414979 0.9683816973579732 1.035097929791967 1.0946614594637345 0.9983185897783651 0.9749622666389289 0.9751362794826726 1.0696966577890061 1.0229047155636835 1.0 17.16845441624327 -5.256694278895006 24.21157131779223 1.0223253199516913 0.9749197873407027 0.20591562193130386 0.03642847454630478 427.6804996291958 2182183.192343158 0.01016479390534572 0.025049354601669082 5.537397765305708e-06 5.256694278895006 -0.047405532610988566 SGIET(ph)FSPPPPPPK ddPTM_PC-9_Lapatinib_30min_R1 1 SGIETFSPPPPPPK 14 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 S(0.001)GIET(0.943)FS(0.056)PPPPPPK 112.75 0.00067156 4063800.0 80732.0 76455.0 73030.0 66250.0 74909.0 75689.0 63292.0 74917.0 94621.0 68815.0 True False 79580.74687556454 76277.97314488122 67025.75530395238 71122.24600352118 70502.99989676035 72451.9579096766 66568.95006986563 78397.91731795478 83963.78657669754 80709.58105977638 0.9860136285012335 0.9450919227097344 0.8304559932520369 0.8812119338204163 0.8735394109472991 0.8976872009286743 0.8247961294776429 0.9713582487795408 1.04031994063395 1.0 16.30045232600113 -7.961363537761734 6.56505765419045 1.0159519319089712 0.8903078209920668 0.5691108105938653 0.046178710303869976 0.13055417185362017 15.44268752436663 0.02729371835769513 0.012726430248920286 1.0930410241218624e-08 7.961363537761734 -0.1256441109169043 SGIETFS(ph)PPPPPPK ddPTM_PC-9_AZD4547_30min_R2 2 SGIETFSPPPPPPK 14 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 S(0.002)GIET(0.175)FS(0.823)PPPPPPK;S(0.081)GIET(0.166)FS(0.752)PPPPPPK 138.21 8.3436e-05 11376400.0 93599.0 106080.0 138632.0 184515.0 164604.0 143905.0 125223.0 166908.0 135651.0 145756.0 True False 123361.53501985643 140368.28549253714 136793.6490994602 141977.91747833235 141751.57587186003 134906.59760106905 136367.604410905 141116.20376428057 142821.2349229948 140653.12680467387 0.8770621586761422 0.9979748668329834 0.97256031349681 1.0094188497885173 1.0078096313401663 0.9591439640614242 0.969531268226122 1.0032923332038666 1.0154145746175398 1.0 17.101782099435354 -4.7594631935452725 24.998282608939444 0.9914748108254404 0.8770620135069374 0.7848044827543197 0.01816885512818854 24.780147689803577 313381.52252248867 0.004770581254909685 0.0303011405349467 1.739950152554772e-05 4.7594631935452725 -0.11441279731850307 SGIETFS(ph)PPPPPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SGIETFSPPPPPPK 14 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 SGIET(0.027)FS(0.973)PPPPPPK;SGIET(0.012)FS(0.988)PPPPPPK;S(0.003)GIET(0.136)FS(0.861)PPPPPPK;SGIET(0.005)FS(0.995)PPPPPPK 150.21 3.4729e-05 18291700.0 208264.0 206105.0 241877.0 295461.0 341256.0 314686.0 339301.0 329220.0 305278.0 258648.0 True False 243518.98179850075 226565.7422995075 247644.26500363022 278907.2780674859 274389.33652669314 298183.312186958 307159.9529534875 320578.3238374237 309742.11322076473 305538.83494355786 0.7970148274064277 0.7415284618119361 0.8105164930977677 0.9128374077848677 0.8980506081244338 0.9759260626952424 1.0053057674656287 1.0492228390431746 1.013756936259783 1.0 18.220996237196793 -6.150701526406052 0.7715110498521812 1.0271217758966218 0.7484940377809385 0.9250307446066008 0.02762436500523991 0.17941325063754315 0.2235593812973571 0.015218850870811491 0.030615493656118962 7.068031455091293e-07 6.150701526406052 -0.2786277381156833 SGIETFS(ph)PPPPPPK ddPTM_PC-9_Lapatinib_30min_R1 3 SGIETFSPPPPPPK 14 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 S(0.003)GIET(0.147)FS(0.85)PPPPPPK;S(0.001)GIET(0.067)FS(0.933)PPPPPPK;SGIET(0.01)FS(0.99)PPPPPPK 114.74 0.00016909 17203200.0 230072.0 210714.0 240192.0 202987.0 223251.0 246361.0 216197.0 219693.0 255649.0 188937.0 True False 226791.13108996282 210226.10467922947 220444.34092793212 217915.3411247818 210119.8151083534 235824.71432554084 227390.62279995435 229900.73880872768 226855.11751668353 221594.50870727224 1.023451043137334 0.948697266487499 0.9948095835675265 0.9833968467722697 0.9482176085235172 1.0642173206424839 1.0261563976765273 1.0374839166814736 1.02373979770573 1.0 17.75756260510665 -6.76078931778253 24.999970520788704 1.0324020371592533 0.9790344869065283 0.5025783971439353 0.02512512826767896 13.633093472465294 524302.3797252971 0.008073723102758796 0.007626774277250649 1.7346452939299736e-07 6.76078931778253 -0.05336755025272499 SGIIPTS(ph)PTPYTYNK ddPTM_PC-9_AZD4547_30min_R2 2 SGIIPTSPTPYTYNK 15 0 F8VRP2;R4GN33;Q8IW41-2;Q8IW41 F8VRP2 MAPKAPK5 MAP kinase-activated protein kinase 5 1 SGIIPT(0.007)S(0.989)PT(0.004)PYTYNK;SGIIPT(0.038)S(0.96)PT(0.002)PYTYNK 136.83 3.5673e-05 3687400.0 29073.9 32841.0 36681.0 49483.0 47991.0 48619.0 33735.0 46630.0 38651.0 41599.0 True False 38318.795425312295 43456.21100924223 36194.58597306037 38075.458854729 41328.27803495925 45578.8462441637 36737.349646645496 39424.40495080159 40694.01295241961 40142.631671750176 0.9545661016609088 1.082545144637937 0.9016495547433631 0.9485043025099941 1.0295358404228254 1.1354224759568812 0.9151704339428972 0.982108130657163 1.0137355538913873 1.0 15.292847579591495 -4.458635487846448 16.052834332088278 0.999280119657647 0.47412734260715883 0.03984552499103278 0.06787629889184953 1973245.5318670825 11049326.329935696 0.0172201420983073 34257204.18838417 3.478279780281081e-05 4.458635487846448 -0.5251527770504881 SGLCS(ph)PSYVAVTPFSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGLCSPSYVAVTPFSLR 17 0 H0YBT0;A0A087WUS5;P01106;P01106-2;H0YBG3;A0A0B4J1R1 H0YBT0 MYC Myc proto-oncogene protein 1 S(0.009)GLCS(0.497)PS(0.406)Y(0.068)VAVT(0.02)PFSLR 64.53699999999999 0.022704 8307100.0 14963.0 7632.0 13592.0 16219.0 21475.0 28946.0 26990.0 37129.0 26408.0 25521.0 True False 17495.940367278894 8389.654521869154 13916.084827947043 15310.302012707474 17267.127909577383 27428.02080347928 24433.311809321673 36154.40309142731 26794.16704097237 30147.755275875166 0.5803397369780129 0.2782845503785392 0.46159605252875896 0.5078421883356299 0.5727500356683233 0.9097865015982709 0.810452107818246 1.1992403003336962 0.8887615942143989 1.0 14.879762966320797 -6.747268959671103 1.2449243050640921 1.0144076433566938 0.42367261100124753 0.8148395067892066 0.11616802024306926 0.1683495513154389 0.5495560478637314 0.05408046946586962 0.04940863247013365 1.7894972706106066e-07 6.747268959671103 -0.5907350323554462 SGLCS(ph)PSYVAVTPFSLR ddPTM_PC-9_Lapatinib_30min_R1 1 SGLCSPSYVAVTPFSLR 17 0 H0YBT0;A0A087WUS5;P01106;P01106-2;H0YBG3;A0A0B4J1R1 H0YBT0 MYC Myc proto-oncogene protein 1 S(0.251)GLCS(0.708)PS(0.041)YVAVTPFSLR 172.42 9.0351e-06 8509700.0 19428.0 15076.0 21603.0 18773.0 19211.0 27623.0 26373.0 23755.0 33903.0 25848.0 True False 19150.953157341155 15041.092448266678 19826.88472999154 20153.62904489217 18081.046750279194 26441.628682358038 27738.464895919933 24858.74402189108 30084.487125582826 30315.79235970495 0.6317154085933165 0.49614709949850927 0.6540117604296887 0.6647897836798721 0.5964233603312347 0.8722064186421741 0.9149839980032737 0.8199932143265617 0.992370140573018 1.0 14.887781910003357 -6.803772419581101 4.596980024255811 0.9133003454038588 0.6068088144417583 0.8538539770476166 0.0645102789868633 0.07667684350090313 3.554287225185856 0.022985904486699665 0.020779708476784613 1.571185926649884e-07 6.803772419581101 -0.3064915309621006 SGLEPAS(ph)SPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGLEPASSPSK 11 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 SGLEPAS(0.459)S(0.459)PS(0.082)K 124.21 0.00052314 20600000.0 177300.0 290510.0 213610.0 218490.0 233660.0 186470.0 224090.0 180380.0 175270.0 169390.0 True False 207313.38816537795 319349.9128862952 218703.27252043656 206248.71365413733 187876.00034234478 176691.18493832604 202862.57292889553 175645.2161284081 177832.9921717373 200099.06610949826 1.0360537517548025 1.5959590371678218 1.0929749787075853 1.030733014722187 0.938914928466159 0.8830185386354429 1.0138106932387432 0.8777912838048503 0.8887247483425209 1.0 17.61035490843539 -5.585016107820923 3.0690271486112586 0.9404684618749752 1.32227174979082 0.5221815802325144 0.13793131624904817 0.1669771540523222 3.16980857397208 0.03604017298717824 0.07215378655615015 2.6000631260018734e-06 5.585016107820923 0.38180328791584484 SGLEPAS(ph)SPSK ddPTM_PC-9_Lapatinib_30min_R1 1 SGLEPASSPSK 11 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 SGLEPAS(0.587)S(0.412)PS(0.001)K 87.21600000000001 0.010494 95047000.0 143940.0 211540.0 198340.0 194200.0 233040.0 197680.0 211120.0 212850.0 193420.0 183330.0 True False 141887.38920463712 211050.1921269786 182033.25081454063 208482.11583220918 219333.04537426785 189225.68721458717 222050.7605819064 222739.78804712783 171635.00279710442 215018.3462281307 0.6598850362940523 0.9815450440822294 0.8465940418935534 0.9696015223324865 1.0200666558078693 0.8800443800912786 1.032706113116108 1.035910618579518 0.798234224232209 1.0 17.71410023603356 -4.757974982423017 24.997915686034744 0.952469733849714 0.6598846262457697 0.5542212945775573 0.07849286674808352 72.99644143315498 526635.8876234988 0.018875668697733664 0.13399145525749892 1.745922724076577e-05 4.757974982423017 -0.2925851076039443 SGLEPAS(ph)SPSKGSEPR ddPTM_PC-9_Lapatinib_30min_R1 1 SGLEPASSPSKGSEPR 16 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 SGLEPAS(0.644)S(0.335)PS(0.021)KGSEPR 106.6 0.0048303999999999995 5699100.0 11201.0 19687.0 19082.0 19226.0 23314.0 22927.0 21014.0 24595.0 19721.0 20081.0 True False 11041.271685988175 19641.415961065668 17513.151618650125 20639.944176055877 21942.71635708757 21946.46565544737 22102.002097708326 25737.77348846184 17499.81330866352 23551.974093749417 0.46880451048553407 0.8339604944741514 0.7435959104293526 0.8763572893676722 0.9316720657785992 0.9318312583093346 0.9384352245688863 1.0928074812757427 0.7430295753130898 1.0 14.523560369149752 -4.3511142815596 0.7264424238692091 0.9450748308309104 6.173814053188658e-16 0.6508404403923707 0.09732841289965999 3.0573347182337263 0.7908838029807747 0.037080241685146814 2.7270792029862614 4.455389924966189e-05 4.3511142815596 -0.9450748308309097 SGLEPASS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 2 SGLEPASSPSK 11 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 SGLEPAS(0.045)S(0.93)PS(0.026)K;SGLEPAS(0.125)S(0.867)PS(0.008)K 167.84 0.0002602 166679000.0 871230.0 1013110.0 941640.0 860280.0 964760.0 1124130.0 1123800.0 1180230.0 1259360.0 957390.0 True False 1148263.0172902409 1340577.9950541507 929153.2383433538 661955.7371935056 830819.7269697901 1053837.973394182 1223816.0229109272 997852.5724873377 1325927.1985656023 923872.0675068353 1.2428809763552522 1.4510428902476071 1.0057163443102792 0.7165015162541518 0.8992800585603192 1.1406752195009784 1.324659621124299 1.080076568588275 1.4351848542664079 1.0 19.81733356379265 -6.9990422711942415 24.993529406506365 1.2189410502938585 1.057974064270824 0.09414241705710902 0.21409534152860166 84.4668614241185 2204225.8033297663 0.08345626673404766 0.07300008032535284 1.0022076854280124e-07 6.9990422711942415 -0.1609669860230345 SGLEPASS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SGLEPASSPSK 11 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 SGLEPAS(0.141)S(0.851)PS(0.008)K;SGLEPAS(0.049)S(0.951)PSK;SGLEPAS(0.208)S(0.792)PS(0.001)K 147.58 6.8179e-05 147712000.0 1507370.0 2176980.0 1798530.0 1884180.0 1929410.0 1518560.0 1989110.0 1540670.0 1543000.0 1373200.0 True False 1762537.9690854202 2393096.187240397 1841413.7761630067 1778615.5031939838 1551355.9608855715 1438924.040327902 1800687.1008906898 1500229.0449747979 1565563.4559307916 1622150.2897547828 1.0865441878088 1.475261695759495 1.1351684167570992 1.0964554359897525 0.9563577251033176 0.8870473034563408 1.1100618187251294 0.9248397355349759 0.9651161583600584 1.0 20.62947605857078 -5.768628075880951 2.08153115542613 0.9755890678494519 1.2806979262670064 0.5442803903792817 0.10759315340973075 0.2147150158105543 1.8988101061258091 0.03100967948776785 0.059839116065278836 1.7036168390566863e-06 5.768628075880951 0.30510885841755453 SGLEPASS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 1 SGLEPASSPSK 11 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 SGLEPAS(0.007)S(0.967)PS(0.026)K 150.09 0.00032673 96194000.0 264200.0 413400.0 368380.0 346290.0 438570.0 369850.0 442790.0 415970.0 331910.0 336480.0 True False 260432.45955165438 412442.79769921995 338093.2183879228 371757.3217895758 412774.1748617956 354032.37766245974 465715.49961189006 435297.4847731443 294526.80063275225 394640.119668583 0.6599239321393993 1.0451111712757122 0.8567127403869935 0.9420160375528366 1.0459508658380743 0.897101840430655 1.1801017595549987 1.1030239022294672 0.7463174318923644 1.0 18.590178104357136 -4.754733941785267 24.939865375034415 0.9835598298501219 0.6599233660462025 0.39199962297650415 0.11934275154548231 233.5351367182145 868518.0182871964 0.029463264936580188 0.2793221447242819 1.7590008860212442e-05 4.754733941785267 -0.3236364638039194 SGLEPASS(ph)PSKGSEPR ddPTM_PC-9_AZD4547_30min_R2 2 SGLEPASSPSKGSEPR 16 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 SGLEPAS(0.097)S(0.851)PS(0.05)KGS(0.001)EPR;SGLEPAS(0.026)S(0.946)PS(0.028)KGSEPR 132.23 3.5487e-05 13263700.0 26918.0 30589.0 34769.0 31955.0 34115.0 38395.0 35292.0 44044.0 44009.0 38353.0 True False 35477.364070818 40476.29604950244 34307.94034233899 24588.26844982855 29378.721117764442 35994.154580404065 38432.91963033682 37238.0118304333 46335.225893845825 37010.27314374466 0.9585815250005595 1.093650292509219 0.9269842513479961 0.6643633337784315 0.7937990893409531 0.9725449590876004 1.0384392322927942 1.0061533911355944 1.25195579383821 1.0 15.175638162625349 -7.322038357417982 1.9300054529573507 1.094362418365658 0.8906799949528372 0.33731457064871506 0.12295275516357036 0.45409742134709474 3.2977756178353617 0.0729906177607036 0.04387681215600142 4.7638890969814024e-08 7.322038357417982 -0.20368242341282072 SGLEPASS(ph)PSKGSEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGLEPASSPSKGSEPR 16 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 SGLEPAS(0.215)S(0.676)PS(0.105)KGS(0.004)EPR;SGLEPAS(0.033)S(0.965)PS(0.003)KGSEPR 180.56 1.8708e-05 11560700.0 30540.0 32568.0 32987.0 41614.0 40155.0 26467.0 37927.0 33380.0 32176.0 25550.0 True False 35709.818807504984 35801.135805586324 33773.53518389414 39282.5024944083 32286.916005079394 25079.02392750936 34334.279992298725 32503.81036903347 32646.51312898845 30182.012746311295 1.183149020168288 1.1861745638538228 1.118995458247621 1.3015203069652543 1.0697403210468577 0.8309261591765248 1.137574232735519 1.076926533768227 1.0816546067815955 1.0 14.881401397551144 -6.504226604728125 24.47666946723544 1.0275784502199212 1.1903718202076303 0.4718619985754672 0.08626099215478521 549.305234127726 720838.3618665686 0.027429957135783684 0.03055693284570061 3.131651275373123e-07 6.504226604728125 0.1627933699877091 SGLEPASS(ph)PSKGSEPR ddPTM_PC-9_Lapatinib_30min_R1 1 SGLEPASSPSKGSEPR 16 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 SGLEPAS(0.047)S(0.907)PS(0.047)KGSEPR 142.19 0.00012411 6128600.0 16103.0 30755.0 28444.0 31186.0 33206.0 31494.0 29991.0 30253.0 30289.0 27818.0 True False 15873.368267071466 30683.788687081553 26105.444117015184 33479.52247344626 31252.88836550784 30147.07503609979 31543.787232909992 31658.664824006366 26877.533862689983 32626.30423484494 0.48652057409918603 0.9404616736918434 0.8001348828573275 1.0261512377393356 0.9579046446863482 0.9240113381859129 0.9668207286322421 0.9703417400918755 0.8237995229010565 1.0 14.993747954045267 -4.760903536886889 24.99236130108766 0.9335700867284958 0.48652006468381287 0.7968417252709279 0.0678435949569708 5.4279341822147185 252933.86590065126 0.016419839627153283 0.09450362129964544 1.734189143579409e-05 4.760903536886889 -0.44705002204468297 SGLLSS(ph)FSLSMTDLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGLLSSFSLSMTDLSK 16 0 A0A1B0GTU3;Q96L93-5;Q96L93-6;Q96L93-4;Q96L93;Q96L93-2 A0A1B0GTU3 KIF16B Kinesin-like protein KIF16B 1 SGLLS(0.067)S(0.792)FS(0.019)LS(0.019)MT(0.102)DLSK 86.539 0.021936 0.0 11186.0 15818.0 12507.0 15591.0 16902.0 16035.0 18468.0 14464.0 17170.0 12822.0 True False 13079.5688664293 17388.30650247987 12805.214313061631 14717.486816703999 13590.174432022206 15194.09637199579 16718.577343258694 14084.335325874785 17421.07876755133 15146.527101103846 0.8635358309612828 1.1480061657970855 0.8454224673145315 0.9716740159948231 0.8972468963549924 1.0031406058018724 1.1037894846562075 0.9298722559872058 1.15016984760036 1.0 13.886699420219765 -6.9950265609571645 23.652114736635497 1.0420212258032793 0.952157290247144 0.1979361355971656 0.09531712255686205 124.3060767358235 591149.747667517 0.0318188415984189 0.02794427642541511 1.0115175891014282e-07 6.9950265609571645 -0.08986393555613525 SGLLSSFS(ph)LSMTDLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGLLSSFSLSMTDLSK 16 0 A0A1B0GTU3;Q96L93-5;Q96L93-6;Q96L93-4;Q96L93;Q96L93-2 A0A1B0GTU3 KIF16B Kinesin-like protein KIF16B 1 SGLLS(0.015)S(0.073)FS(0.443)LS(0.443)MT(0.025)DLS(0.001)K 66.498 0.023437 2630800.0 11536.0 15376.0 15025.0 19255.0 20616.0 15207.0 18132.0 16759.0 18117.0 14681.0 True False 13488.8169536142 16902.427663556096 15383.252982629807 18176.204775552273 16576.44279319428 14409.518149606482 16414.405695688052 16319.094007628286 18381.92685100334 17342.549085267947 0.7777874456225472 0.9746218725085967 0.8870237533706904 1.0480699628517987 0.9558250469232085 0.8308765959813255 0.9464817204773934 0.9409858912546449 1.0599322372175564 1.0 14.082028347451185 -4.757440600333999 24.984211602872204 0.9543973250162623 0.7777871876079818 0.41163639502228233 0.06514748934322992 123.46694711644312 771309.8999400524 0.01628797223774552 0.12092475168978514 1.7480723347909672e-05 4.757440600333999 -0.17661013740828047 SGLLSTFGGS(ph)TGR ddPTM_PC-9_AZD4547_30min_R2 1 SGLLSTFGGSTGR 13 0 Q9P212;Q9P212-2 Q9P212 PLCE1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 1 SGLLSTFGGS(0.943)T(0.057)GR 90.689 0.0054859999999999996 3008400.0 2908.3 4318.7 8011.8 12533.0 11334.0 12410.0 10533.0 12803.0 6696.7 14004.0 True False 3833.078903602051 5714.635318218515 7905.558297182876 9643.710482919767 9760.46973908082 11634.000738190245 11470.416594875258 10824.59053367173 7050.6738904159865 13513.724222485864 0.28364341616680944 0.4228764198628364 0.5850021923659354 0.713623448588164 0.72226349882441 0.8609026310328359 0.8487975931748933 0.8010072098156621 0.5217417326516234 1.0 13.72213769869027 -5.231281748631729 0.9836964400321988 0.7943221470357831 0.1915618961061788 0.7085500790435104 0.11302297983691958 0.596345392441121 0.7403261929768593 0.03977175401727699 0.3270458250627779 5.871083422987778e-06 5.231281748631729 -0.6027602509296043 down SGLLSTFGGS(ph)TGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGLLSTFGGSTGR 13 0 Q9P212;Q9P212-2 Q9P212 PLCE1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 1 SGLLS(0.005)T(0.005)FGGS(0.956)T(0.034)GR 91.307 0.005179100000000001 1759200.0 12582.0 9932.2 12300.0 16524.0 17777.0 14684.0 17046.0 16449.0 13467.0 12649.0 True False 14711.884094172485 10918.203176376945 12593.278648009767 15598.213851530798 14293.724463262273 13913.94519029536 15431.27947764716 16017.231179156126 13663.92939793906 14942.163570571087 0.9845886122641474 0.7306976078002908 0.8428015520331006 1.0439059763909837 0.9566033992168358 0.9311867805877306 1.032733941424614 1.0719485905443042 0.9144545455820376 1.0 13.867101439761 -5.748956815901806 24.966757354653353 0.9935405137877912 0.8404960176229138 0.42816126567823354 0.07388705823145024 191.7612235635015 383544.02959679515 0.01955311987414224 0.03356759789606048 1.7825560072008962e-06 5.748956815901806 -0.15304449616487736 SGLLSTFGGST(ph)GR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGLLSTFGGSTGR 13 0 Q9P212;Q9P212-2 Q9P212 PLCE1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 1 SGLLSTFGGS(0.32)T(0.679)GR 91.09299999999999 0.015316999999999999 0.0 11226.0 10768.0 11450.0 13060.0 17306.0 12541.0 11315.0 12822.0 12710.0 8282.3 True False 13126.34007639329 11836.975876767174 11723.011424366814 12328.290541091283 13915.013532160474 11883.32788283125 10243.16128649405 12485.436086031974 12895.85970504236 9783.815427349267 1.3416381547530496 1.209852737376728 1.1982044746670915 1.2600698196563782 1.4222481643779816 1.2145903580328277 1.0469495630365988 1.2761316051742666 1.318080844922096 1.0 13.256181472198728 -6.990910364298182 24.99683240008346 1.1757969532214858 1.280050281240906 0.23204459324325444 0.10670375866638972 369.70547432058623 1016697.7415706146 0.03841872961888092 0.03383565103341437 1.0211502210654402e-07 6.990910364298182 0.10425332801942022 SGLMST(ph) ddPTM_PC-9_Lapatinib_30min_R1 1 SGLMST 6 0 E7EVX8;Q8WWY3 E7EVX8 PRPF31 U4/U6 small nuclear ribonucleoprotein Prp31 1 SGLMS(0.094)T(0.906) 50.126999999999995 0.034095 8342100.0 131310.0 109080.0 117520.0 90266.0 100190.0 109810.0 88988.0 93865.0 101600.0 88067.0 True False 129437.49532069528 108827.43196185521 107857.95924031899 96904.46275854875 94297.02118111882 105113.68227961262 93595.36321837183 98226.31057102964 90156.73810456943 103289.26360809871 1.2531553696791613 1.0536180447056867 1.044232047674915 0.9381852418488019 0.9129411701384729 1.0176631975849508 0.9061480346446501 0.9509827753610579 0.8728568193364524 1.0 16.656330775645166 -1.522886658375011 0.6823445210743212 0.9365902954316756 36.074322702625466 0.8140411056764023 0.04476390697056512 99.77065836829387 0.5682066343695812 0.017264357369939826 5331.37145881469 0.02999945338776478 1.522886658375011 35.13773240719379 SGLNGS(ph)ILAER ddPTM_PC-9_AZD4547_30min_R2 3 SGLNGSILAER 11 0 Q96H22-5;Q96H22-4;Q96H22;Q96H22-3 Q96H22-5 CENPN Centromere protein N 1 S(0.118)GLNGS(0.882)ILAER;S(0.096)GLNGS(0.904)ILAER;S(0.015)GLNGS(0.985)ILAER 96.464 0.0057938 22054800.0 35364.0 41346.1 37401.2 50188.0 43939.2 56351.0 48665.0 56241.0 57332.0 47090.3 True False 46609.01638310456 54710.41825794674 36905.23565049005 38617.931996870415 37839.00052580028 52827.36306186612 52996.09072340303 47550.24573961035 60362.4524744022 45441.68293017178 1.0256886052113556 1.2039698957016582 0.8121450014780635 0.8498349864421368 0.8326936434978827 1.1625309551814704 1.1662440144402173 1.0464015123004733 1.328349844946511 1.0 15.471728645511165 -6.779930360776976 24.9549034167569 1.1452015963196926 0.9466081244680179 0.34975557085385856 0.133432400552776 291.8707008894782 393897.7933547133 0.04926099718486745 0.04352230628435538 1.6598530439281519e-07 6.779930360776976 -0.19859347185167475 SGLNGS(ph)ILAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGLNGSILAER 11 0 Q96H22-5;Q96H22-4;Q96H22;Q96H22-3 Q96H22-5 CENPN Centromere protein N 1 S(0.209)GLNGS(0.791)ILAER 84.75299999999999 0.011836 2830900.0 14919.0 18194.0 22856.0 18397.0 23124.0 14319.0 19776.0 14091.0 13455.0 15249.0 True False 17444.492036318512 20000.180080042905 23400.97372186268 17366.275733878738 18593.018197022935 13568.086432841134 17902.674114158766 13721.126180648624 13651.753920640844 18013.52298898241 0.9684109014648642 1.1102869823007742 1.299078127925081 0.964068813440905 1.032170009630818 0.7532167050909345 0.9938463522714883 0.761712530582766 0.7578614093972983 1.0 14.136792743008398 -6.407631734377516 1.8477976244607748 0.8481099352457315 1.114416796958223 0.44404336131215405 0.12214911074254717 0.3037955286466976 2.0594277197670348 0.04408044024544401 0.052113071119891594 3.9117245493964174e-07 6.407631734377516 0.2663068617124915 SGLNGS(ph)ILAER ddPTM_PC-9_Lapatinib_30min_R1 3 SGLNGSILAER 11 0 Q96H22-5;Q96H22-4;Q96H22;Q96H22-3 Q96H22-5 CENPN Centromere protein N 1 S(0.035)GLNGS(0.965)ILAER;S(0.009)GLNGS(0.991)ILAER;S(0.273)GLNGS(0.727)ILAER 87.083 0.010565999999999999 17370500.0 45667.0 50695.1 41431.0 49345.2 50942.4 58688.7 50768.9 48863.0 58256.0 38797.0 True False 45015.78020569786 50577.71861064765 38024.703108284935 52974.21061876168 47946.06818861191 56178.72111104176 53397.46522786449 51133.35336315148 51694.595817124005 45503.00975624701 0.9892923665234636 1.1115246855446512 0.8356524834725818 1.1641913557484835 1.0536900404050635 1.2346154993259344 1.1734930395573155 1.1237356306113684 1.136069813712201 1.0 15.473674353801542 -5.810902784759776 24.999996639689325 1.13512181098701 0.9920914865351759 0.37081557952179967 0.08716731547812671 109.71140988131641 55450.22406441958 0.023556033414336222 0.034939317044282256 1.545600377841611e-06 5.810902784759776 -0.14303032445183417 SGLQLS(ph)LEQGTGENSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGLQLSLEQGTGENSFR 17 0 P23497;P23497-5;P23497-2;P23497-3;P23497-4;E9PHV6;P23497-7;P23497-6;C9JBL0 P23497 SP100 Nuclear autoantigen Sp-100 1 SGLQLS(1)LEQGTGENSFR 134.08 2.7016e-05 3252600.0 8340.3 7169.1 11616.0 11108.0 13842.0 12846.0 14092.0 13101.0 11747.0 10589.0 True False 9752.14806156627 7880.800869068681 11892.969493925317 10485.654772621898 11129.759465628415 12172.333145909444 12757.103742755122 12757.112631656913 11918.777651859375 12508.701877522117 0.7796291059658782 0.630025477162448 0.9507756768347594 0.8382688208010143 0.8897613497071479 0.9731092214918704 1.019858324841795 1.0198590354592418 0.9528388931610222 1.0 13.610644457459658 -5.586589190759571 0.6235794285440543 1.0050239664164244 0.6509833723793154 0.677098558903768 0.067342397351184 0.8667445764077717 0.4899118708732848 0.03781149303561399 0.1939144319960975 2.5906623241754956e-06 5.586589190759571 -0.3540405940371091 SGLS(ph)DIILGK ddPTM_PC-9_AZD4547_30min_R2 1 SGLSDIILGK 10 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;K7EJR2;M0R330;M0QX30;M0R1V5 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 S(0.022)GLS(0.978)DIILGK 92.611 0.007321899999999999 4971800.0 12199.0 9087.7 13306.0 15851.0 13957.0 15601.0 14708.0 11843.0 10548.0 12142.0 True False 16078.028245037114 12025.121305340603 13129.55374601404 12196.796845508752 12019.311465356544 14625.46700374747 16016.98350682856 10012.936475066326 11105.54574583121 11716.912275737166 1.3722069318834744 1.0263046289287034 1.1205643122550388 1.0409565727282357 1.0258087781578404 1.2482355982158544 1.366996963866989 0.8545712589997492 0.9478218735859323 1.0 13.51630481011252 -1.522878747896217 0.10186786062137221 0.9039447076721929 1.759650560608935 0.16222374127323014 0.15194947869624656 292.0571164843842 2.110757103086359 1.970174650183934 34.94875549631069 0.029999999819301456 1.522878747896217 0.8557058529367421 SGLS(ph)DIILGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGLSDIILGK 10 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;K7EJR2;M0R330;M0QX30;M0R1V5 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 S(0.022)GLS(0.978)DIILGK;S(0.186)GLS(0.814)DIILGK 94.465 0.0062919 15663200.0 39607.0 41100.0 34061.0 43237.0 39002.0 34009.0 41943.0 39336.0 34117.0 27661.0 True False 46311.68282609202 45180.13637956265 34873.14341706183 40814.57106624531 31359.838078199653 32225.508170577177 37969.85539897661 38303.47167993711 34615.89658197723 32675.72033564448 1.4173117639145871 1.3826821846763593 1.0672494151267502 1.249079458601025 0.95972905129778 0.986221813614429 1.162020454605158 1.1722303681903399 1.0593766939612437 1.0 14.995931420105954 -5.240790327575335 6.455912916731967 1.0889508888204564 1.4033086407675845 0.6828370890581115 0.08659751644434242 0.09996127343314104 17.487538846254324 0.0230224611322145 0.05862694939128759 5.743937060097232e-06 5.240790327575335 0.3143577519471281 SGLS(ph)DIILGK ddPTM_PC-9_Lapatinib_30min_R1 1 SGLSDIILGK 10 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;K7EJR2;M0R330;M0QX30;M0R1V5 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 S(0.001)GLS(0.999)DIILGK 92.866 0.0071589 4162500.0 18227.0 15691.0 16276.0 13315.0 14571.0 14264.0 13670.0 13595.0 14624.0 10942.0 True False 17967.07963757756 15654.66845355216 14937.850107176888 14294.229517537919 13713.962427688215 13653.961971008031 14377.765712176302 14226.673330987545 12976.89112245299 12833.310120701472 1.4000347119013965 1.2198465015116826 1.1639904254382953 1.1138380809858115 1.0686223818098308 1.0639470130923403 1.1203474066276526 1.1085739530316838 1.0111881502434752 1.0 13.647605715120573 -1.52287874528079 0.5555930874624986 1.0612806460298196 16.794281297756715 0.8999947904185182 0.03493208858733224 40.46443824224891 0.3640736154126411 0.017240973870093438 761.3500993708917 0.029999999999968753 1.52287874528079 15.733000651726895 SGLS(ph)LEELR ddPTM_PC-9_AZD4547_30min_R2 2 SGLSLEELR 9 0 A0A087WWA3;Q4R9M9;O60333-2;O60333;O60333-4 A0A087WWA3 KIF1B;KIF1Bbeta Kinesin-like protein;Kinesin-like protein KIF1B 1 S(0.004)GLS(0.996)LEELR;S(0.005)GLS(0.995)LEELR 84.31 0.013306 21205000.0 188326.0 203774.0 269950.0 250240.0 252480.0 266080.0 312330.0 386650.0 297630.0 263580.0 True False 248209.7505758552 269639.96048224246 266370.2866178037 192551.03416945974 217427.51012203377 249441.97553728122 340126.76493661717 326902.12683310005 313362.1141763123 254352.14442750794 0.9758508273422347 1.0601049229962032 1.0472500132339988 0.7570254011533922 0.8548286888298756 0.9806953902382917 1.337227825234851 1.2852344043290318 1.232001070333506 1.0 17.956467731963045 -7.170078812829157 5.881511629925072 1.2364507271322698 0.9402209883395741 0.5544093477523886 0.11709417673651179 0.17055825505458777 8.850931918596782 0.04724962663781711 0.036392442862694906 6.759602955520648e-08 7.170078812829157 -0.29622973879269565 SGLS(ph)LEELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGLSLEELR 9 0 A0A087WWA3;Q4R9M9;O60333-2;O60333;O60333-4 A0A087WWA3 KIF1B;KIF1Bbeta Kinesin-like protein;Kinesin-like protein KIF1B 1 S(0.001)GLS(0.999)LEELR;S(0.03)GLS(0.97)LEELR 106.16 0.0025881 18804700.0 102893.0 134400.0 165333.0 148961.0 177208.0 138808.0 168028.0 143350.0 139423.0 123787.0 True False 120310.75267061585 147742.3437813433 169275.16574889413 140615.19810807824 142485.36449827204 131528.66412248142 152111.17142262723 139587.21439187962 141461.79761259787 146228.60320264703 0.8227579969692139 1.0103518774408211 1.1576063919198396 0.9616121266863938 0.9744014602998873 0.8994728886263511 1.040228574240212 0.9545821496936299 0.9674016882767922 1.0 17.157866013240422 SGLS(ph)LEELR ddPTM_PC-9_Lapatinib_30min_R1 3 SGLSLEELR 9 0 A0A087WWA3;Q4R9M9;O60333-2;O60333;O60333-4 A0A087WWA3 KIF1B;KIF1Bbeta Kinesin-like protein;Kinesin-like protein KIF1B 1 S(0.004)GLS(0.996)LEELR;S(0.003)GLS(0.997)LEELR;S(0.041)GLS(0.959)LEELR 84.68700000000001 0.013015 21460360.0 129864.1 164768.3 169036.6 168017.8 149646.4 171262.8 154360.6 172382.5 183327.0 170904.9 True False 128012.21411984085 164386.7891246838 155139.0632481459 180374.3895029502 140844.4929681421 163938.28927708624 162352.6365757836 180392.02026325566 162678.78274110614 200445.58424853504 0.6386382349092653 0.8201068122351776 0.7739709698757293 0.8998671144548721 0.7026570003832422 0.8178692980026792 0.8099586587773393 0.8999550722932629 0.8115857645404583 1.0 17.612851110169892 -14.522878744967173 0.07334986649026032 1.6773794788354552 0.5730364146643696 0.5271720345688882 0.06669019044662113 237.3835637023274 1.2422507159954514 26.691395965518023 3.0014915715704293 3.0000000021632655e-15 14.522878744967173 -1.1043430641710856 SGLTVPT(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 3 SGLTVPTSPK 10 0 Q53EL6;Q53EL6-2;Q5VZS7 Q53EL6 PDCD4 Programmed cell death protein 4 1 SGLTVPT(0.938)S(0.062)PK;SGLTVPT(0.636)S(0.364)PK;SGLTVPT(0.854)S(0.146)PK 136.81 0.00027236 608922000.0 6286470.0 6952540.0 5401620.0 7428410.0 7268900.0 7041990.0 6483640.0 6409500.0 6290900.0 6394280.0 True False 8285436.693300982 9199812.590670103 5329990.989444192 5715904.842290429 6259738.705347151 6601653.252081264 7060671.399525006 5419059.050657563 6623424.130873112 6170418.203467353 1.342767446239727 1.4909544681267206 0.8637973657035274 0.9263399422552075 1.0144755993734111 1.0698874913164858 1.1442776108039794 0.8782320536414245 1.0734157576468966 1.0 22.55693684145772 -5.256416939367225 24.999178647623708 0.9980175033749626 1.4168609922528799 0.7774562755371148 0.08999890423461457 182.3406678528177 907592.1749716965 0.023621334014056156 0.05857989448683206 5.540935065017518e-06 5.256416939367225 0.4188434888779172 SGLTVPT(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SGLTVPTSPK 10 0 Q53EL6;Q53EL6-2;Q5VZS7 Q53EL6 PDCD4 Programmed cell death protein 4 1 SGLTVPT(0.961)S(0.039)PK;SGLTVPT(0.759)S(0.241)PK;SGLTVPT(0.5)S(0.5)PK;SGLTVPT(0.928)S(0.072)PK 163.84 0.00027236 532745000.0 6939400.0 7650520.0 4896290.0 7679170.0 7898260.0 6192800.0 7956470.0 5251020.0 5332610.0 6056240.0 True False 8114103.360602494 8410013.065074742 5013036.122883223 7248931.00110504 6350652.651133828 5868038.666198663 7202775.561745598 5113186.288915573 5410589.332943046 7154188.370830538 1.1341752467248103 1.1755369902426003 0.7007134650413537 1.013242959978632 0.8876831754985749 0.8202242325801992 1.0067914329895427 0.7147122809574522 0.7562827608794043 1.0 22.77035667452973 -5.242900642645221 24.571992310655915 0.862200178972421 1.1548562075098765 0.5224780304073127 0.11181469804368153 502.7214861935483 666324.126126793 0.027833168145440148 0.07332953243734233 5.7160939380467054e-06 5.242900642645221 0.29265602853745554 SGLTVPT(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 5 SGLTVPTSPK 10 0 Q53EL6;Q53EL6-2;Q5VZS7 Q53EL6 PDCD4 Programmed cell death protein 4 1 SGLTVPT(0.954)S(0.046)PK;SGLTVPT(0.931)S(0.069)PK;SGLT(0.002)VPT(0.926)S(0.072)PK;SGLTVPT(0.951)S(0.049)PK;SGLTVPT(0.956)S(0.044)PK 177.57 0.00035779 696612000.0 7163330.0 6767860.0 5471020.0 5383520.0 5586960.0 6138330.0 5863870.0 6322350.0 5269460.0 4414770.0 True False 7061179.600606156 6752189.435986074 5021213.854347937 5779442.019696261 5258345.997185984 5875807.9350461215 6167472.496463736 6616109.461873428 4675957.924926225 5177857.11218874 1.363726238019209 1.3040509403187925 0.9697474738203836 1.1161841461579507 1.015544825446761 1.134795303874724 1.191124506303086 1.2777698029362425 0.9030681657705389 1.0 22.303923722592124 -5.123387560650619 5.7777588885724285 1.0919326730369883 1.3489504558290248 0.4847998882880593 0.10593656113925715 0.1878715068293405 7.902207529541907 0.026988113625823415 0.07494155871584234 7.526835756078168e-06 5.123387560650619 0.2570177827920366 SGLTVPTS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 SGLTVPTSPK 10 0 Q53EL6;Q53EL6-2;Q5VZS7 Q53EL6 PDCD4 Programmed cell death protein 4 1 SGLT(0.021)VPT(0.207)S(0.772)PK;SGLTVPT(0.054)S(0.946)PK 96.756 0.0054084 16656900.0 172240.0 222346.0 181905.0 256260.0 225041.0 228621.0 190332.0 215513.0 176095.0 225890.0 True False 227008.7371854409 294214.9962869878 179492.82084538456 197183.2161775328 193797.94164041668 214325.29272891168 207271.17927805922 182210.4178460665 185403.02219493242 217981.65985556477 1.0414120955673862 1.3497236257487693 0.8234308380086517 0.904586267983219 0.8890561791704299 0.9832262625714667 0.9508652214842187 0.8358979281412923 0.8505441343908517 1.0 17.733847231693673 -5.270522248550848 24.999408719604123 0.902730437004979 1.1955678666321776 0.6300806138609459 0.08913741738077162 333.6841733683316 918423.178535081 0.022156575744657573 0.04719277948970891 5.363863921005828e-06 5.270522248550848 0.2928374296271986 SGLTVPTS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGLTVPTSPK 10 0 Q53EL6;Q53EL6-2;Q5VZS7 Q53EL6 PDCD4 Programmed cell death protein 4 1 SGLTVPT(0.225)S(0.775)PK;SGLTVPT(0.029)S(0.971)PK 115.91 0.0010842 74321000.0 567230.0 568140.0 389276.0 623400.0 619560.0 451480.0 564190.0 447510.0 428444.0 476860.0 True False 663250.8356968269 624541.1844935463 398557.81617745047 588472.9190900702 498161.66554867296 427803.5940148833 510745.8388181252 435763.33667603944 434709.18296358606 563310.9431783177 1.1774151447416012 1.1086970563180518 0.7075272032329146 1.0446680047963977 0.8843457979671778 0.7594448487031448 0.9066854549929223 0.7735751310233241 0.771703777865323 1.0 19.103571972848535 -5.125657618050132 5.82860507488422 0.854586725720237 1.1602778161893887 0.5579371332405461 0.10282627672487687 0.15040134158836765 6.371280988216269 0.025597979158811967 0.0709387059989802 7.487595626536306e-06 5.125657618050132 0.30569109046915177 SGMS(ph)PEQSR ddPTM_PC-9_AZD4547_30min_R2 3 SGMSPEQSR 9 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.013)GMS(0.987)PEQSR;S(0.007)GMS(0.993)PEQSR;S(0.001)GMS(0.999)PEQSR 87.713 0.0094027 1856777000.0 150070.0 136875.0 206792.0 281826.0 219131.0 207329.0 161235.0 235634.0 182261.0 204563.0 True False 197789.13835008763 181117.16701349025 204049.80296450757 216855.36986829538 188708.44312639165 194364.68485481446 175584.60264641748 199222.17963064954 191894.94436679364 197401.3116341309 1.0019646612919957 0.9175074142829297 1.033680076770205 1.098550805327075 0.955963471388423 0.9846169878296219 0.8894804253978357 1.0092241940108964 0.9721057209713839 1.0 17.590772050258323 SGMS(ph)PEQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGMSPEQSR 9 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.001)GMS(0.999)PEQSR;S(0.004)GMS(0.996)PEQSR 82.494 0.013819 1343230000.0 240240.0 240689.0 272974.0 285262.0 319314.0 293586.0 296966.0 244580.0 274311.0 215090.0 True False 280907.88704371295 264583.0132618148 279482.73541966 269279.6949718824 256746.71391472823 278189.83333138487 268835.2306323456 238160.03415393038 278322.27942957357 254084.11434849637 1.1055704437248906 1.0413205640196708 1.0999614680212846 1.059805315504865 1.010479205176046 1.0948729874148118 1.058056035190051 0.9373275254322871 1.095394256123516 1.0 17.95494665357831 -3.0173172990852253 0.13534916402965902 0.9842231395911326 1.2509005754275566 0.20820684289445535 0.04593702130956547 82.90203823832277 1.1110973146621175 0.24457238853782695 4.020766652957253 0.0009609099732082142 3.0173172990852253 0.266677435836424 SGMS(ph)PEQSR ddPTM_PC-9_Lapatinib_30min_R1 6 SGMSPEQSR 9 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.001)GMS(0.999)PEQSR;S(0.007)GMS(0.993)PEQSR;S(0.003)GMS(0.997)PEQSR;S(0.069)GMS(0.93)PEQS(0.001)R;S(0.032)GMS(0.968)PEQSR;S(0.005)GMS(0.988)PEQS(0.007)R 83.081 0.013066 1480385500.0 212751.90000000002 174890.9 217180.3 185500.0 211408.2 192003.0 166589.5 176779.4 213600.90000000002 168849.2 True False 209718.0188920797 174485.95086631502 199324.57407420164 199142.2888098596 198973.5853205132 183791.4792708536 175214.68918131612 184993.216288928 189542.9173248065 198034.55924258355 1.0589970745216466 0.8810883894895207 1.0065140894425295 1.0055936174550177 1.0047417283201534 0.9280778060849328 0.8847682437421738 0.9341461257896887 0.957120403881753 1.0 17.59539269311145 -6.769844539841493 24.97389657304969 0.9332032469163549 0.98688893368757 0.19447669840806248 0.049853807216172656 289.7257997772769 860845.0747448058 0.01710174699700137 0.015327290270067451 1.6988516649888203e-07 6.769844539841493 0.0536856867712151 SGMS(ph)PPPCK ddPTM_PC-9_AZD4547_30min_R2 1 SGMSPPPCK 9 0 Q9H6T0-2;Q9H6T0 Q9H6T0-2 ESRP2 Epithelial splicing regulatory protein 2 1 SGMS(1)PPPCK 68.847 0.036947 10609000.0 43450.0 48251.0 59707.0 62834.0 62593.0 66052.0 51003.0 64447.0 58198.0 59947.0 True False 57266.19618385628 63847.192150267845 58915.24616813921 48348.59207562277 53903.04238382616 61921.75799830323 55542.16819409694 54488.196994731035 61274.22746642816 57848.27377644667 0.9899378571806685 1.103700905527516 1.0184443255094495 0.8357827972959884 0.9318003609257769 1.070416694499795 0.9601352740228408 0.9419156949315276 1.059223092865675 1.0 15.819986288729801 -5.530972999253627 24.998425515117606 0.967550653025306 1.0503827204263096 0.17255359914719182 0.06774040101766494 277.732892172354 857751.006194836 0.018801586108395392 0.032630404676857565 2.944604698646419e-06 5.530972999253627 0.08283206740100368 SGMS(ph)PPPCK ddPTM_PC-9_Lapatinib_30min_R1 2 SGMSPPPCK 9 0 Q9H6T0-2;Q9H6T0 Q9H6T0-2 ESRP2 Epithelial splicing regulatory protein 2 1 S(0.012)GMS(0.988)PPPCK;S(0.001)GMS(0.999)PPPCK 74.533 0.02729 13977400.0 104371.0 140901.0 128092.0 104112.0 132637.0 120274.0 115281.0 126330.0 135041.0 92410.0 True False 102882.65040070289 140574.75239143195 117560.77020941873 111768.74378745083 124835.55243437519 115130.16139238782 121249.68610573499 132199.75299033863 119831.26053522783 108382.94537141526 0.9492512871664123 1.297019119656688 1.084679603479608 1.0312392176133693 1.1518007008074824 1.0622534846036031 1.1187155478219102 1.2197468202889858 1.1056283820722954 1.0 16.725778233307416 -7.5193461008965095 24.972931253366955 1.1314587765566333 1.103101577384704 0.0 0.09826548837747956 900.3566792264348 6364968.147229655 0.04342564188180499 0.02572067545701325 3.0245021607045684e-08 7.5193461008965095 -0.02835719917192936 SGNFGGS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 SGNFGGSR 8 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 SGNFGGS(1)R 68.786 0.042647000000000004 7112300.0 22571.0 25963.0 25131.0 18107.0 29851.0 14491.0 25990.0 25300.0 28495.0 28226.0 True False 22249.133400985524 25902.884268661972 23064.826188465373 19438.649183181304 28095.222869324043 13871.253710170886 27335.63502995334 26475.530362190897 25285.593034347505 33104.82649121913 0.6720812570000022 0.7824503860647802 0.6967209507829074 0.5871847474668775 0.8486745241445728 0.41901001093753376 0.8257295967765899 0.7997483499638152 0.7638038230182045 1.0 15.014753948464973 -8.702543474972666 0.7889459644631458 0.9970870903778636 0.6848200148541318 0.3822880059544499 0.11804101835536665 0.9236017781213615 1.2040956338389166 0.11239403776254463 0.04038998261493579 1.9836110778595227e-09 8.702543474972666 -0.3122670755237318 SGNLTEDDKHNNAK ddPTM_PC-9_AZD4547_30min_R2 1 SGNLTEDDKHNNAK 14 1 A0A0A0MSQ0;P13797-3;P13797-2;P13797 A0A0A0MSQ0 PLS3 Plastin-3 0 75.483 0.0078523 6741600.0 24794.0 21794.0 26309.0 34895.0 37922.0 29393.0 29513.0 33293.0 28851.0 32156.0 False True 32677.976252762517 28838.484295101396 25960.125470004787 26850.496872375756 32657.184881367826 27555.05106346703 32139.599825743226 28148.331847030604 30376.004959516147 31030.228227524654 1.0531013827277063 0.9293674569083858 0.8366076227237494 0.8653013015404971 1.0524313466827813 0.8880067159488357 1.0357513193291479 0.9071261622904297 0.9789165821401148 1.0 14.921386687486244 -6.239175263003124 24.97193852311215 0.9708790457590638 0.915650607791584 0.1241096650076281 0.07111103648690761 1803.39540837133 2022729.439582384 0.021117750660679262 0.027241263918887204 5.765337516438061e-07 6.239175263003124 -0.05522843796747978 SGNLTEDDKHNNAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SGNLTEDDKHNNAK 14 1 A0A0A0MSQ0;P13797-3;P13797-2;P13797 A0A0A0MSQ0 PLS3 Plastin-3 0 ;;; 89.44 0.0023984 23785900.0 166365.0 179956.0 166955.0 216245.0 240826.0 198216.0 203428.0 193123.0 211397.0 173872.0 False True 194527.30864147295 197820.84239222796 170935.84038036308 204129.49372574966 193637.8740839064 187821.2040206745 184157.82714882088 188053.725880733 214488.28120116726 205393.6172300055 0.9470951983071404 0.9631304276154924 0.8322354057815943 0.9938453613052628 0.9427648078618982 0.9144451836122398 0.8966092989277062 0.9155772629007511 1.044279194718 1.0 17.648031823893817 -8.256935015333985 24.794928336348192 1.0221396028267553 0.9253379752251835 0.458252565839396 0.04193599621921082 275.89247265407505 1518714.7890261724 0.030195847283703458 0.010539951063553876 5.5343291469453345e-09 8.256935015333985 -0.09680162760157185 SGNLTEDDKHNNAK ddPTM_PC-9_Lapatinib_30min_R1 3 SGNLTEDDKHNNAK 14 1 A0A0A0MSQ0;P13797-3;P13797-2;P13797 A0A0A0MSQ0 PLS3 Plastin-3 0 ;; 88.163 0.0026244 24802800.0 162734.0 140461.0 137538.0 139641.0 136658.0 133868.0 127428.0 130757.0 134225.0 112521.0 False True 160413.38331823927 140135.77118439812 126230.15655203312 149910.66496872046 128620.04511996542 128142.77770154952 134025.5983300075 136832.44757189677 119107.16704808889 131970.1049251917 1.2155281941252594 1.0618751213680946 0.9565056921307116 1.1359441219941329 0.9746150099136066 0.9709985286000058 1.0155754472270895 1.0368442735531758 0.9025314264590888 1.0 17.009851628559588 SGNTPNS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 SGNTPNSPR 9 0 Q96EA4-2;Q96EA4-3;Q96EA4 Q96EA4-2 SPDL1 Protein Spindly 1 SGNTPNS(1)PR;SGNT(0.006)PNS(0.994)PR 96.604 0.005051300000000001 26831600.0 31821.6 17351.1 22760.6 29534.5 26608.0 24753.5 24264.0 21982.2 30757.3 34673.0 True False 41940.20686960185 22959.503755746235 22458.779572488136 22725.777328476324 22913.938487512136 23205.659731893014 26423.448994403614 18585.35609070363 32383.068085727547 33459.10882363981 1.2534765074188077 0.6861959138470745 0.6712306562277705 0.6792104789240506 0.6848340943056674 0.6935528335260847 0.7897236335157467 0.5554647671181411 0.9678401255818262 1.0 15.030111399556995 -10.864825897267515 15.548889599396297 0.9999799194234433 0.7560235383402266 0.10381697027782799 0.18990043249188449 0.0 8.455951314197192e-11 0.17647037730709073 0.04280035326057277 1.3651302890162947e-11 10.864825897267515 -0.2439563810832167 SGNTPNS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SGNTPNSPR 9 0 Q96EA4-2;Q96EA4-3;Q96EA4 Q96EA4-2 SPDL1 Protein Spindly 1 SGNTPNS(1)PR;SGNTPNS(1)PR;S(0.019)GNT(0.242)PNS(0.739)PR 109.72 0.0023498 46654200.0 25331.9 38165.7 43752.0 30476.5 80840.7 80087.3 42372.9 53205.8 74700.6 80925.5 True False 29620.090342168824 41954.53846767578 44795.21361038399 28769.00051114614 65000.54515482062 75887.38100236602 38359.03215877012 51809.204126204946 75792.9549553491 95596.65254409458 0.3098444302587516 0.4388703720386441 0.4685855876566588 0.3009415052255752 0.6799458289069138 0.7938288526092738 0.40125915644459165 0.5419562583774323 0.7928410978657343 1.0 16.544672480573603 -10.66123712659195 0.0954978769168792 1.8110051824658846 1.494882145840581e-10 0.635489837951327 0.13411877654973833 44.975148180031326 0.8078008661405036 12.691633206404505 3.9972006172053565 2.1815384575393018e-11 10.66123712659195 -1.8110051823163964 SGNTPNS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 SGNTPNSPR 9 0 Q96EA4-2;Q96EA4-3;Q96EA4 Q96EA4-2 SPDL1 Protein Spindly 1 S(0.005)GNT(0.138)PNS(0.858)PR;SGNTPNS(1)PR;SGNT(0.003)PNS(0.997)PR;SGNTPNS(1)PR 106.79 0.0025461 62491400.0 27093.7 36950.4 27416.699999999997 30529.3 47165.6 29334.1 52411.899999999994 52767.1 50226.0 34759.5 True False 26707.33886962394 36864.8436190258 25162.60475752251 32774.52656475931 44391.412139137414 28079.548924126942 55125.531728603746 55218.85210176923 44569.01897677265 40767.63326087762 0.6551113403792674 0.9042674462636243 0.6172201510081192 0.8039349832998807 1.088888625323691 0.6887706417599004 1.352188668295949 1.3544777482768326 1.0932451901627314 1.0 15.315136584060339 -7.260834952746409 24.999953167544838 1.2295177222947065 0.8040404842921502 0.598804370693598 0.16231592582869214 36.85980822049833 1524621.9015247663 0.06413996328733611 0.046654051744073693 5.4848536914476624e-08 7.260834952746409 -0.4254772380025562 SGPEAEGLGSETSPTVDDEEEMLYGDSGSLFS(ph)PSKEEARR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGPEAEGLGSETSPTVDDEEEMLYGDSGSLFSPSKEEARR 40 2 Q10570 Q10570 CPSF1 Cleavage and polyadenylation specificity factor subunit 1 1 SGPEAEGLGSET(0.001)S(0.011)PT(0.042)VDDEEEMLY(0.009)GDS(0.042)GS(0.181)LFS(0.679)PS(0.035)KEEARR 68.741 3.1977e-06 3284700.0 9804.3 1886.3 6780.4 18389.0 16589.0 21106.0 13286.0 23767.0 17867.0 13340.0 True False 11463.974346248242 2073.5593978775923 6942.070450810197 17358.723947942388 13338.504535132904 19999.16420501048 12027.453897689798 23143.14143321805 18128.27107395689 15758.436400618097 0.7274817154954909 0.1315840826565928 0.4405304101451275 1.101551163239871 0.8464357881731036 1.2691084125723315 0.7632390417375446 1.468619147538667 1.1503851405743428 1.0 13.943836772910744 -5.749498804091501 6.546027907524593 1.0905162735211376 0.3981399678300001 0.6252320216088343 0.2310756334520564 0.08937063725747565 15.903641544547982 0.061981871740287096 0.10255920160348783 1.780332811315762e-06 5.749498804091501 -0.6923763056911374 SGPIS(ph)PGIHSCDLTVEGLATVTR ddPTM_PC-9_AZD4547_30min_R2 2 SGPISPGIHSCDLTVEGLATVTR 23 0 Q9BUB4-2;Q9BUB4 Q9BUB4-2 ADAT1 tRNA-specific adenosine deaminase 1 1 S(0.066)GPIS(0.933)PGIHS(0.001)CDLTVEGLATVTR;S(0.015)GPIS(0.985)PGIHSCDLTVEGLATVTR 100.47 3.1423000000000004e-06 37840000.0 37371.3 38170.0 55890.0 67908.0 56263.0 53665.0 44793.0 60490.0 49544.0 48760.0 True False 49254.596028670836 50507.706044967425 55148.86208212273 52252.85976814139 48451.85362007275 50309.319066476986 48779.490224460984 51142.66042191696 52162.79469391933 47052.92724138892 1.046791324501173 1.0734232492243245 1.1720601738378653 1.1105124129701005 1.0297309107148025 1.0692069976514376 1.0366940610137712 1.0869177205394058 1.1085982903107385 1.0 15.52199685776934 -6.241311578924192 24.549038142775277 1.0593131347318143 1.1038460691693506 0.22046212661123032 0.04131840240703787 1113.6356073546704 1358252.840110279 0.012647780665535431 0.016303470083977825 5.737047175410782e-07 6.241311578924192 0.04453293443753625 SGPIS(ph)PGIHSCDLTVEGLATVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SGPISPGIHSCDLTVEGLATVTR 23 0 Q9BUB4-2;Q9BUB4 Q9BUB4-2 ADAT1 tRNA-specific adenosine deaminase 1 1 S(0.234)GPIS(0.761)PGIHS(0.004)CDLTVEGLATVTR;S(0.084)GPIS(0.912)PGIHS(0.003)CDLTVEGLATVTR;S(0.064)GPIS(0.936)PGIHS(0.001)CDLTVEGLATVTR 107.58 1.0169e-06 22661100.0 32672.7 38461.5 38917.6 42823.0 56594.0 56609.0 64342.0 55696.0 55486.0 50876.0 True False 38203.54279475994 42279.703536801695 39845.54317981988 40423.76614403921 45504.81196342829 53640.32438555095 58247.059964259905 54234.03901478998 56297.37778080102 60099.41606580559 0.6356724456844828 0.7034960787390633 0.6629938489949915 0.6726149568537801 0.7571589699574285 0.892526548457937 0.9691784675658502 0.9024054236301841 0.9367375170360799 1.0 15.875063353130518 -6.688022114727908 2.019213011824024 0.945325792542734 0.6697321535670566 0.9542222482087154 0.02852565248289169 0.06194518681603948 0.5189596929708717 0.010848172481552983 0.01047992274144659 2.0510577341676708e-07 6.688022114727908 -0.27559363897567735 SGPIS(ph)PGIHSCDLTVEGLATVTR ddPTM_PC-9_Lapatinib_30min_R1 2 SGPISPGIHSCDLTVEGLATVTR 23 0 Q9BUB4-2;Q9BUB4 Q9BUB4-2 ADAT1 tRNA-specific adenosine deaminase 1 1 S(0.011)GPIS(0.989)PGIHSCDLTVEGLATVTR;S(0.023)GPIS(0.977)PGIHSCDLTVEGLATVTR 125.16 1.0620999999999998e-07 21436100.0 34203.9 37247.0 41767.0 32639.8 42012.0 45872.0 50036.0 44081.0 53750.0 36819.0 True False 33716.146113772964 37160.75685994888 38333.078485282414 35040.2397751809 39540.93675876997 43910.161492854815 52626.6192519717 46129.16418560225 47696.10898740752 43183.11509176637 0.7807715131741746 0.8605390505289009 0.8876867359805476 0.8114338139043134 0.915657350673832 1.0168363583670015 1.2186851073651679 1.0682222458378783 1.1045082988119501 1.0 15.398179698068352 -6.768977496604885 2.478168780414995 1.1045311467895413 0.8426885842266049 0.8006816886810687 0.05909561930091721 0.11639573764500977 1.465837322086575 0.02180799774240929 0.02008568129094397 1.7022467096949096e-07 6.768977496604885 -0.2618425625629365 SGPKPFSAPKPQT(ph)SPSPK ddPTM_PC-9_AZD4547_30min_R2 1 SGPKPFSAPKPQTSPSPK 18 2 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 1 SGPKPFS(0.004)APKPQT(0.727)S(0.229)PS(0.04)PK 86.016 0.014818000000000001 208090000.0 54466.0 61622.0 65029.0 88261.0 78262.0 75109.0 71653.0 71382.0 72695.0 78766.0 True False 71785.05503682194 81540.10641611178 64166.67297080625 67913.79006885672 67396.67220045367 70412.42235654568 78029.97818974637 60351.55209517733 76537.50929021613 76008.42631450442 0.9444354858735373 1.072777195500912 0.8442047294243421 0.8935034358933566 0.8867000077278616 0.926376531796569 1.0265964179665719 0.7940113356045191 1.006960846334622 1.0 16.21387174453043 -5.64834174163341 0.0013605983380378553 1.8650418939388287 2.3721913670069275e-06 0.004034929678665589 0.0828432188911907 5605697.9922596235 1650.48800982277 1123231.4554082125 1139196.3108512305 2.247285545195683e-06 5.64834174163341 -1.8650395217474616 SGPKPFSAPKPQT(ph)SPSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGPKPFSAPKPQTSPSPK 18 2 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 1 SGPKPFSAPKPQT(0.948)S(0.043)PS(0.009)PK 99.39200000000001 0.0054095 203610000.0 24257.0 26856.0 19873.0 36088.0 35136.0 25017.0 30902.0 36119.0 31090.0 30612.0 True False 28363.23100241156 29522.08619487919 20346.847688772206 34066.1063588746 28251.35302588643 23705.06448008848 27974.73884889431 35170.91452124386 31544.632433498606 36161.71327554135 0.784344225791856 0.816390693934488 0.5626627127353 0.9420490146388015 0.7812504017887549 0.655529352258922 0.7736010358728094 0.9726008901528559 0.8723212916693969 1.0 15.142175411162427 -7.728947665914387 7.666395903879669 0.9418669224173721 0.7574661420898542 0.4365818659362283 0.09826374294256084 0.18954368366429677 36.317428766607236 0.0469829790275818 0.02643618451075009 1.86660461001727e-08 7.728947665914387 -0.18440078032751794 SGPKPFSAPKPQT(ph)SPSPK ddPTM_PC-9_Lapatinib_30min_R1 1 SGPKPFSAPKPQTSPSPK 18 2 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 1 SGPKPFSAPKPQT(0.428)S(0.428)PS(0.144)PK 94.564 0.0078829 208120000.0 96351.0 86528.0 84329.0 72389.0 76913.0 76893.0 74297.0 66000.0 71009.0 57259.0 True False 94977.0170713908 86327.64973226463 77395.79513935372 77712.72854262497 72389.12855677593 73604.46563633773 78143.735121987 69066.60094484565 63011.21866208042 67156.14185717836 1.4142714939369117 1.2854766123381316 1.1524753060405426 1.1571946570113782 1.077922682198251 1.0960198665503014 1.1636126340934843 1.0284480173344426 0.938279313247134 1.0 16.03523172889228 -1.5228787452803392 0.3249214186306236 1.0092381139862947 5.0407886151613015 0.8585900702188071 0.04977100380605757 22.058114275523707 0.3144993700349473 0.04980676482885129 53.119786153695436 0.029999999999999888 1.5228787452803392 4.031550501175007 SGPKPFSAPKPQTS(ph)PSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGPKPFSAPKPQTSPSPK 18 2 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 1 SGPKPFSAPKPQT(0.154)S(0.766)PS(0.08)PK 76.76100000000001 0.020329 218920000.0 74742.0 95402.0 64370.0 106590.0 125240.0 100260.0 116620.0 106680.0 98686.0 91509.0 True False 87394.34437821005 104872.8800701469 65904.82492458445 100618.1078694424 100700.12104286248 95002.18910235725 105572.90934431621 103879.76303680312 100129.09605443059 108098.85731515448 0.8084668658746141 0.9701571568365198 0.609671800067633 0.9307971459503731 0.9315558327252108 0.8788454518569532 0.9766329817578547 0.9609700381378603 0.9262733995652829 1.0 16.72199174723673 -5.956526689472552 24.99999983122167 0.9409839210209168 0.8062926657748414 0.37770889699083243 0.08650765231086222 151.74555570284582 87262.64054369646 0.023580393725292952 0.03497535759114778 1.1052825423983537e-06 5.956526689472552 -0.1346912552460754 SGPKPFSAPKPQTSPS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 SGPKPFSAPKPQTSPSPK 18 2 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 1 SGPKPFSAPKPQT(0.184)S(0.319)PS(0.497)PK 80.41 0.011845 248670000.0 212010.0 169130.0 157820.0 161650.0 149210.0 155730.0 144000.0 141390.0 165200.0 123470.0 True False 208986.6985221276 168738.38987631586 144844.64880281713 173538.2802485921 140433.76115814675 149069.79092436074 151455.61540258882 147959.49556957174 146593.43636687877 144811.6249865663 1.4431624432190069 1.1652268241031696 1.0002280467210687 1.1983725772339802 0.9697685608539668 1.029404862615066 1.0458802283079058 1.0217376925595403 1.01230433938213 1.0 17.14381789617616 SGPPPEHLPS(ph)SPLPPHPPSQPCTPELPAGPR ddPTM_PC-9_Lapatinib_30min_R1 1 SGPPPEHLPSSPLPPHPPSQPCTPELPAGPR 31 0 A0A494BYR6;Q86Y91-6 A0A494BYR6 KIF18B Kinesin-like protein KIF18B 1 SGPPPEHLPS(0.5)S(0.5)PLPPHPPSQPCTPELPAGPR 87.53200000000001 4.9681999999999994e-09 6916900.0 32946.0 19200.0 43744.0 27093.0 37151.0 43401.0 29971.0 37188.0 43736.0 31859.0 True False 32476.183998443572 19155.54357964449 40147.537176723155 29085.509599598532 34965.85122167623 41544.84040267246 31522.751730770724 38915.890241468565 38809.99111950244 37365.785700550914 0.869142275200833 0.5126492918724325 1.0744464869135946 0.7783995185512639 0.9357718716767329 1.1118417456978547 0.8436260910821944 1.041484596452492 1.0386504764151188 1.0 15.189430238109782 -5.587874305240505 0.9261736122326855 0.9981024322908925 0.6929103801133066 0.3088246436930764 0.14170969970415534 0.9490394987341139 1.3590146712238467 0.05386548075462476 0.22859027919247032 2.583007663977263e-06 5.587874305240505 -0.3051920521775858 SGPPS(ph)PPSTATSFGGPR ddPTM_PC-9_AZD4547_30min_R2 1 SGPPSPPSTATSFGGPR 17 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2;A0A087X0E3 A0A0A0MS59 SRCAP Helicase SRCAP 1 SGPPS(0.856)PPS(0.093)T(0.023)AT(0.01)S(0.019)FGGPR 99.915 0.0012109000000000002 8579600.0 23311.0 38020.0 19854.0 22251.0 19726.0 28661.0 25235.0 30962.0 33335.0 24135.0 True False 30723.41310107879 50309.22147837728 19590.722987626847 17121.375724523074 16987.385395545123 26868.823139183776 27480.866113327374 26177.53433597939 35097.02004524872 23290.040996122276 1.3191652649385266 2.1601173431491003 0.8411630958867202 0.7351372085336274 0.7293840916112373 1.1536614788980988 1.179940650078841 1.1239797448333335 1.506953983081965 1.0 14.50742555859373 -5.273353564148585 24.996028030079163 1.0261701286095515 1.7396413279126635 0.4862118538856681 0.29015759227658916 547.9937255298577 1149694.6654250338 0.07802078755926309 0.16447037188335006 5.329008780888712e-06 5.273353564148585 0.713471199303112 SGPPS(ph)PPSTATSFGGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGPPSPPSTATSFGGPR 17 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2;A0A087X0E3 A0A0A0MS59 SRCAP Helicase SRCAP 1 S(0.138)GPPS(0.833)PPS(0.022)T(0.005)AT(0.001)SFGGPR 80.411 0.0057617 4774200.0 15979.0 22253.0 10586.0 17999.0 18114.0 13320.0 17876.0 13764.0 13288.0 8819.1 True False 18683.92910036418 24462.13077504643 10838.41038762857 16990.57438354533 14564.691732437008 12621.475751480135 16182.65586896755 13402.709584163484 13482.311861573802 10417.93301804281 1.7934391657160302 2.3480790990574123 1.040360920813902 1.6308968731243871 1.3980404469113432 1.2115143886624162 1.5533461235487713 1.2865037201670755 1.2941446098975484 1.0 13.34678144599258 -5.260716598185534 24.99996759627206 1.3330258115508804 2.0707591507792613 0.6476952057230287 0.22589999839139938 35.6299183744527 1232328.7424627524 0.05435443516466966 0.12751183778118955 5.486348635408191e-06 5.260716598185534 0.7377333392283809 SGPPS(ph)PPSTATSFGGPRPR ddPTM_PC-9_AZD4547_30min_R2 1 SGPPSPPSTATSFGGPRPR 19 1 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2;A0A087X0E3 A0A0A0MS59 SRCAP Helicase SRCAP 1 S(0.036)GPPS(0.936)PPS(0.027)T(0.001)ATSFGGPRPR 117.55 2.8898e-05 101430000.0 31044.0 36295.0 38271.0 47069.0 49281.0 48706.0 41592.0 48102.0 38249.0 42641.0 True False 40915.346244686596 48026.64896259082 37763.50153417284 36217.969258800775 42439.18380198006 45660.406120410495 45293.60742561966 40668.9411739965 40270.764053118844 41148.15156891027 0.9943422653181931 1.1671641891899136 0.917744785471853 0.8801845982837654 1.0313752181773639 1.1096587423603612 1.100744643408029 0.988354023774039 0.9786773528739906 1.0 15.328540003823031 -6.500341159535886 24.518504339551306 1.0423576225396862 0.9921735253634573 0.06576006008083346 0.08087756890290061 1843.8668154684647 2005935.0208524428 0.027427052022022287 0.03084422939231812 3.159794511996969e-07 6.500341159535886 -0.05018409717622896 SGPPS(ph)PPSTATSFGGPRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGPPSPPSTATSFGGPRPR 19 1 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2;A0A087X0E3 A0A0A0MS59 SRCAP Helicase SRCAP 1 SGPPS(0.803)PPS(0.025)T(0.033)AT(0.033)S(0.106)FGGPRPR 97.12899999999999 0.0050638 0.0 6943.2 6357.6 8405.4 7757.7 8248.4 8047.0 8080.6 5826.5 7495.0 5561.4 True False 8118.546625549071 6988.7405120853455 8605.816613657016 7323.061219802742 6632.185231634834 7625.001154066111 7315.147069522214 5673.560548687043 7604.600195853068 6569.637795981823 1.2357677664535183 1.0637938847039419 1.3099377592659032 1.114682642668936 1.0095206825087475 1.1606425484719687 1.1134779871724991 0.863603249505955 1.1575372085968358 1.0 12.681598117257572 -6.552352396793659 0.6667970951629024 1.016387790982189 1.1974281861198566 0.27389527727868923 0.10267540504426102 1.0681650881788791 1.0546138990337295 0.07275495957277915 0.09587106259461312 2.8031581661893065e-07 6.552352396793659 0.18104039513766756 SGPPS(ph)PPSTATSFGGPRPR ddPTM_PC-9_Lapatinib_30min_R1 2 SGPPSPPSTATSFGGPRPR 19 1 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2;A0A087X0E3 A0A0A0MS59 SRCAP Helicase SRCAP 1 SGPPS(0.997)PPS(0.002)T(0.001)AT(0.001)SFGGPRPR;SGPPS(0.935)PPS(0.025)T(0.007)AT(0.007)S(0.025)FGGPRPR 114.28 0.00038866 23625800.0 25616.0 21370.0 21763.0 17478.0 20356.3 19844.1 17478.6 14860.8 18797.1 16065.8 True False 25250.71114260092 21320.51907796888 19973.730147609404 18763.390424898815 19158.982456025642 18995.414101856466 18383.55638455338 15551.287020017642 16679.97265576182 18842.752123667124 1.3400755355097618 1.131497083761432 1.0600219127503 0.9957882108596744 1.0167825979073049 1.0081018938840465 0.9756301130482432 0.8253193014456051 0.8852195553117328 1.0 14.201722076198324 -1.5228787453053778 0.44592479344340685 0.9213726718444814 9.943023862313074 0.8419421575805016 0.05266903958936804 34.054248971440536 0.4139440643630611 0.03599878743292713 278.99546136510753 0.029999999998270282 1.5228787453053778 9.021651190468592 SGPPSPPS(ph)TATSFGGPR ddPTM_PC-9_AZD4547_30min_R2 1 SGPPSPPSTATSFGGPR 17 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2;A0A087X0E3 A0A0A0MS59 SRCAP Helicase SRCAP 1 S(0.064)GPPS(0.109)PPS(0.408)T(0.408)AT(0.009)S(0.003)FGGPR 75.877 0.008685799999999999 10526000.0 26537.0 32110.0 24439.0 20630.0 22260.0 38041.0 35389.0 28996.0 23741.0 21009.0 True False 34975.2139961103 42488.92955472633 24114.922891841077 15874.072230322736 19169.58323556901 35662.29025636544 38538.552442422915 24515.33446179376 24995.90079178788 20273.481304641926 1.7251706044241246 2.095788528682434 1.1894811024054164 0.7829968613574089 0.945549654127722 1.7590609979845944 1.9009341248954081 1.2092316111580006 1.2329357951002073 1.0 14.307306225122721 -5.267019611908572 24.960523373753635 1.2735122612151346 1.9104795815221827 0.3780101633716392 0.33673552858815764 480.13082167346477 2147646.5267564207 0.09835575361519279 0.2143715257587129 5.407299040654632e-06 5.267019611908572 0.6369673203070481 SGPPSPPS(ph)TATSFGGPRPR ddPTM_PC-9_Lapatinib_30min_R1 1 SGPPSPPSTATSFGGPRPR 19 1 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2;A0A087X0E3 A0A0A0MS59 SRCAP Helicase SRCAP 1 S(0.002)GPPS(0.076)PPS(0.702)T(0.194)AT(0.013)S(0.013)FGGPRPR 51.468999999999994 0.024537 50369000.0 28323.0 28800.0 33873.0 31369.0 28789.0 28807.0 30530.0 19803.0 22284.0 20464.0 True False 27919.108826197924 28733.315369466734 31088.092693561222 33675.98090391638 27095.68762135173 27574.99176239685 32110.69401556273 20723.11967440578 19774.141259077027 24001.17513343401 1.163239244369588 1.1971628559736969 1.2952737739184705 1.4030971698967027 1.128931707331572 1.148901735398133 1.3378800761647722 0.8634210433112566 0.8238822119810016 1.0 14.55081742361963 -7.7694159191233885 24.996131413364086 0.8827385789135549 1.2383395013394203 0.7437025253171226 0.09229692477127635 90.00492058824118 282043.6633188941 0.05082123020913348 0.025100673595804784 1.700529149954043e-08 7.7694159191233885 0.3556009224258654 SGPQILT(ph)PLGDR ddPTM_PC-9_AZD4547_30min_R2 1 SGPQILTPLGDR 12 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 SGPQILT(1)PLGDR 97.2 0.0098909 5709400.0 16723.0 20346.0 25087.0 27381.0 21901.0 24612.0 22936.0 32542.0 26946.0 22600.0 True False 22040.566139991446 26922.446612284723 24754.329988445385 21068.733482233 18860.424188777943 23073.00774926176 24977.259567080513 27513.381640767435 28370.310548650697 21808.780878904636 1.0106280705177342 1.2344773768774242 1.1350625294415215 0.966066539859297 0.8648087343122145 1.0579687089056864 1.1452845395517137 1.261573574127694 1.3008664127618865 1.0 14.412621504451678 -7.411944580671691 3.4303555113866167 1.2099560382096755 1.046018597240745 0.22849530138261487 0.11809543192105386 0.360999064866228 7.863347943649165 0.058618920650870536 0.03681292334056204 3.873070651395726e-08 7.411944580671691 -0.16393744096893048 SGPQPTEVPGT(ph)PGPLNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGPQPTEVPGTPGPLNR 17 0 C9JXU1;A6NN40;Q2M3G4-2;Q2M3G4 C9JXU1 SHROOM1 Protein Shroom1 1 S(0.009)GPQPT(0.419)EVPGT(0.572)PGPLNR 80.859 0.026955 0.0 4490.3 4669.5 5141.2 5545.5 6036.8 6079.5 8171.9 5311.7 3733.1 5174.2 True False 5250.419102532407 5133.057100349588 5263.785706109576 5234.803613753578 4853.932375531399 5760.680317651913 7397.798472567458 5172.27350321136 3787.6895251686574 6112.241501055334 0.8590005976736806 0.8397994580978712 0.8611874555677709 0.856445808440282 0.7941329501940202 0.9424824455410146 1.2103249636471596 0.8462155008630335 0.6196891147895054 1.0 12.577485831552067 -6.778301013942484 24.656506889001253 0.9320423101716544 0.8438406386782603 0.078900761081791 0.1379405893793415 596.2458177947137 871874.6034159317 0.051503959410087785 0.045543697342853816 1.666092026855949e-07 6.778301013942484 -0.08820167149339408 SGPS(ph)PLSSPNGK ddPTM_PC-9_AZD4547_30min_R2 2 SGPSPLSSPNGK 12 0 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 SGPS(0.994)PLS(0.004)S(0.001)PNGK;S(0.02)GPS(0.98)PLSSPNGK 133.98 5.5997e-05 53150000.0 194231.0 147815.0 228191.0 267463.0 246929.0 216985.0 192602.0 230627.0 167934.0 185132.0 True False 255992.4177442248 195593.30807013004 225165.0382426491 205803.53761215758 212647.1706547992 203416.89364836537 209743.20488048703 194988.8964312352 176810.64839594407 178650.58502979562 1.4329223590369435 1.0948372099509704 1.2603655241604483 1.1519891612884074 1.1902965255855926 1.1386298769435275 1.1740415227048135 1.0914540044675176 0.9897009201870529 1.0 17.446781112783185 -1.5228787453607573 0.1341255148114799 0.9394406252469083 2.184161049261817 0.5949337791573337 0.07773225019878087 58.893597178790614 0.5331022348898447 0.36741053439813404 13.93290966773277 0.029999999994444804 1.5228787453607573 1.2447204240149086 SGPS(ph)PLSSPNGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGPSPLSSPNGK 12 0 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 S(0.005)GPS(0.995)PLSSPNGK 117.03 0.00064957 20309000.0 102000.0 92546.0 91641.0 124970.0 111340.0 130080.0 109590.0 122620.0 109070.0 85279.0 True False 119266.58540817005 101733.35526479362 93826.06899042804 117968.33605820652 89523.72626087768 123258.37580724728 99208.84183710835 119401.35492662902 110664.94240983225 100739.40763180742 1.1839119189987461 1.0098665225094332 0.9313740391779258 1.1710247144729016 0.8886663954594418 1.2235368333487175 0.9848066826013795 1.1852497223631606 1.0985268328587128 1.0 16.620268627230416 -6.777045165542617 24.9993646750367 1.102900966513495 1.037044165969429 0.07260020299853753 0.10923830367323628 657.3948079712784 1053093.528723211 0.03628048012108586 0.03210091750152049 1.6709168340924554e-07 6.777045165542617 -0.06585680054406606 SGPS(ph)PLSSPNGK ddPTM_PC-9_Lapatinib_30min_R1 2 SGPSPLSSPNGK 12 0 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 SGPS(0.99)PLS(0.008)S(0.002)PNGK;S(0.003)GPS(0.895)PLS(0.085)S(0.017)PNGK 98.0 0.0037954 54855000.0 173609.0 145853.0 148696.0 142400.0 134272.0 135521.0 133468.0 117521.0 144340.0 106471.0 True False 171133.30382400824 145515.28633968192 136470.7888631589 152872.57103247487 126374.38494890876 129725.08274488086 140378.3199760604 122981.45469150314 128082.90923241682 124874.37048631039 1.370443776073082 1.165293452715618 1.0928646793708545 1.2242109444646516 1.012012188383867 1.038844738433354 1.1241563775606753 0.9848414387401074 1.0256941335008225 1.0 16.930117879593105 -1.5228787452803376 0.4217628729757111 1.0242600542449332 6.964158960586776 0.7287744148882105 0.060192385291460246 42.711829460967 0.5454743493423163 0.04090725372795777 214.32215983973472 0.029999999999999995 1.5228787452803376 5.939898906341843 SGQGFHGNSEVNAILS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 SGQGFHGNSEVNAILSPR 18 0 Q8TB72-4;A0A0A0MR59;Q8TB72-3;Q8TB72;C9JW01;Q8TB72-2 Q8TB72-4 PUM2 Pumilio homolog 2 1 SGQGFHGNS(0.016)EVNAILS(0.984)PR;SGQGFHGNSEVNAILS(1)PR;SGQGFHGNSEVNAILS(1)PR;SGQGFHGNSEVNAILS(1)PR 149.8 4.8655e-05 59326600.0 59104.3 59635.6 129919.4 191349.0 180659.3 162802.4 80600.5 169049.0 120869.1 138943.6 True False 77898.23795418856 78911.64146228075 128196.5838681719 147236.44436257996 155577.8746015107 152622.34019171164 87773.78835614205 142926.36140956578 127257.99386684185 134079.22685514024 0.5809866284383497 0.5885448724099314 0.9561256197179302 1.09813017136245 1.1603428678000784 1.1382996737936553 0.6546412178448285 1.065984379250516 0.9491253555954042 1.0 17.032726209557246 -5.287325810011327 4.276331608034453 1.0099333322087414 0.5768928762714121 0.6094543502410581 0.13435645643821215 0.13337745493786454 5.903244544352802 0.03746549578423941 0.09088399246509432 5.160290962729144e-06 5.287325810011327 -0.4330404559373293 SGQGFHGNSEVNAILS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SGQGFHGNSEVNAILSPR 18 0 Q8TB72-4;A0A0A0MR59;Q8TB72-3;Q8TB72;C9JW01;Q8TB72-2 Q8TB72-4 PUM2 Pumilio homolog 2 1 SGQGFHGNSEVNAILS(1)PR;SGQGFHGNSEVNAILS(1)PR;SGQGFHGNSEVNAILS(1)PR;SGQGFHGNSEVNAILS(1)PR 157.53 6.6321e-06 49241000.0 124168.0 108344.0 169497.0 173380.0 227169.0 202628.0 202803.0 170504.0 177468.0 160217.0 True False 145187.18997021217 119099.6762994488 173538.45130095223 163666.08070554418 182656.86519631103 192001.8309737925 183592.03167342918 166028.45066392072 180063.1337635295 189263.073822926 0.7671184190216043 0.6292811053617259 0.916916584918801 0.8647544256766627 0.965095100205359 1.0144706365354124 0.970036193352737 0.8772363637042928 0.9513907289279052 1.0 17.53003343587916 -5.339304423467578 5.565200325371599 0.9435709375506478 0.6991527225574734 0.7649307552959239 0.05478660342370325 0.09441509495856541 5.0390205518592746 0.014812768949744233 0.03184331286994092 4.57820859674553e-06 5.339304423467578 -0.2444182149931744 SGQGFHGNSEVNAILS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 5 SGQGFHGNSEVNAILSPR 18 0 Q8TB72-4;A0A0A0MR59;Q8TB72-3;Q8TB72;C9JW01;Q8TB72-2 Q8TB72-4 PUM2 Pumilio homolog 2 1 SGQGFHGNSEVNAILS(1)PR;SGQGFHGNSEVNAILS(1)PR;SGQGFHGNSEVNAILS(1)PR;SGQGFHGNSEVNAILS(1)PR;SGQGFHGNSEVNAILS(1)PR 147.75 3.0525e-05 50457600.0 268314.7 180025.0 255086.0 186093.0 259505.0 263349.0 205096.0 220086.0 309706.0 156087.3 True False 264488.48317511054 179608.16317320315 234113.8137404355 199778.90000804965 244241.42610646 252086.17716650266 215714.86733756456 230311.99902344437 274823.64893123804 183066.78183174605 1.4447650225161983 0.9811073389506477 1.2788437716439787 1.0912897359591074 1.334165727187681 1.3770175814757661 1.1783397576509804 1.258076406429216 1.5012207358505072 1.0 17.482010506782807 SGQLER ddPTM_PC-9_Lapatinib_30min_R1 1 SGQLER 6 0 A0PK00 A0PK00 TMEM120B Transmembrane protein 120B 0 118.01 0.0012493 0.0 16249.0 14275.0 14643.0 11180.0 15651.0 12423.0 12907.0 15980.0 16213.0 11869.0 False True 16017.286280298349 14241.947114553383 13439.10906361459 12002.214495386692 14730.438951049899 11891.697249427436 13575.261305563974 16722.489137858105 14386.921209541184 13920.540835551616 1.1506224125568356 1.0230886344717964 0.9654157279071012 0.8621945538735307 1.0581800754055393 0.8542554050096441 0.9751963997615787 1.2012815691148009 1.0335030355141432 1.0 13.764927642863308 -10.040371135111604 5.664638656196821 0.9999995433830215 1.00914193546963 0.0 0.10429512351518187 0.0 1.3893453694668744e-10 0.10563121119319573 0.025619331661460625 9.112317950143349e-11 10.040371135111604 0.009142392086608497 SGRES(ph)VSTASDQPSHSLER ddPTM_PC-9_AZD4547_30min_R2 1 SGRESVSTASDQPSHSLER 19 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.099)GRES(0.549)VS(0.33)T(0.018)AS(0.004)DQPSHSLER 89.04299999999999 0.00050968 4393100.0 9204.5 8914.4 13505.0 20810.0 16301.0 14990.0 10706.0 14996.0 11256.0 13987.0 True False 12131.339534506436 11795.805469406809 13325.914875989749 16012.576011295001 14037.887525741708 14052.67293033616 11658.813259729854 12678.712773798428 11850.969180420569 13497.319387311463 0.8987962117804551 0.8739369004260052 0.9873008479385286 1.1863523083219085 1.0400500368197867 1.0411454694883173 0.8637873139973298 0.939350430257834 0.8780239127749624 1.0 13.720385291222824 -7.254540678728047 24.88020610857153 0.915236283154347 1.0077447919309357 0.18178754604201508 0.08720683482875814 934.1960466728266 3369191.543966701 0.03767172538431058 0.028496977156773975 5.5649250726028856e-08 7.254540678728047 0.09250850877658867 SGRES(ph)VSTASDQPSHSLER ddPTM_PC-9_Lapatinib_30min_R1 1 SGRESVSTASDQPSHSLER 19 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.176)GRES(0.47)VS(0.326)T(0.023)AS(0.006)DQPSHSLER 84.156 0.0006469 1975000.0 5357.4 3868.3 6105.2 3793.1 3449.4 6267.1 6587.7 4937.3 4792.6 6010.5 True False 5281.002493573167 3859.3431890176425 5603.254022753519 4072.057227410668 3246.5130737813247 5999.070742323646 6928.7788721363395 5166.704982499804 4252.806919684638 7049.406916512175 0.7491413896399162 0.5474706219579568 0.7948546720474796 0.5776453644451262 0.4605370511633903 0.8510036111366654 0.9828881995599825 0.7329276127325797 0.603285775676118 1.0 12.783286169889948 -6.793180507371063 24.993919177995778 0.8266333356972201 0.6282731265348379 0.35832999305696434 0.13903834711675958 243.3609052855869 191628.04736108525 0.05000852103989202 0.044107178962369556 1.6099763358652054e-07 6.793180507371063 -0.19836020916238217 SGRESVS(ph)TASDQPSHSLER ddPTM_PC-9_Lapatinib_30min_R1 1 SGRESVSTASDQPSHSLER 19 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 SGRES(0.016)VS(0.835)T(0.148)AS(0.001)DQPSHSLER 130.17 1.7888e-05 3223300.0 4968.2 3430.8 5890.5 3548.1 5752.6 5437.8 5867.7 5194.2 9796.1 4922.6 True False 4897.3525569437015 3422.856193387723 5406.205827987555 3809.039110114629 5414.243378046749 5205.237970130924 6171.500795123399 5435.541494359363 8692.760060493822 5773.464851047803 0.8482519047561017 0.5928599691338768 0.9363884543276303 0.6597492508200412 0.9377806079592119 0.9015795721327109 1.0689422997012545 0.94146957409343 1.505640076585243 1.0 12.495221673406787 -7.2042754629634125 0.9063351998668824 1.1929472866537283 0.7579487474872441 0.4960769082715003 0.16634882888425373 0.4702142385219554 0.7620342507046951 0.11746969496974055 0.07142060211319483 6.24776285899034e-08 7.2042754629634125 -0.43499853916648423 SGRESVST(ph)ASDQPSHSLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGRESVSTASDQPSHSLER 19 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.028)GRES(0.11)VS(0.268)T(0.419)AS(0.174)DQPSHSLER 91.565 0.0026857 0.0 7222.5 4000.0 5851.1 6568.9 10111.0 7213.2 7174.4 9324.4 6932.4 6033.5 True False 8445.126599122625 4397.093564920942 5990.612414420317 6200.865829661144 8129.822132420811 6834.927093887122 6494.788893842063 9079.644380018444 7033.773235187706 7127.325788840278 1.184894145339296 0.6169345551463019 0.8405133414555305 0.8700129632589894 1.1406553275774496 0.9589749783276382 0.9112518616745962 1.2739202120148683 0.9868741016723196 1.0 12.799145155879287 -6.182698676343786 7.51187473934927 1.0477577437766843 0.8555187205197343 0.2013923526676179 0.16064338976545825 0.4184555718299247 35.43058206832493 0.046259083410897094 0.05984517184394584 6.566006731832377e-07 6.182698676343786 -0.19223902325694997 SGRS(ph)PTGNTPPVIDSVSEK ddPTM_PC-9_AZD4547_30min_R2 1 SGRSPTGNTPPVIDSVSEK 19 1 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 S(0.267)GRS(0.329)PT(0.329)GNT(0.074)PPVIDSVSEK 50.883 0.026407 9783900.0 26509.0 17810.0 26698.0 38472.0 31023.0 31329.0 18582.0 28639.0 27104.0 30993.0 True False 34938.310578546494 23566.73420646765 26343.967075836703 29602.874786474826 26715.991945959442 29369.992677418406 20235.762001896128 24213.500608749873 28536.662106087315 29907.944503534993 1.168194978241214 0.787975723429678 0.8808350929206438 0.9897997096716523 0.8932740911967963 0.9820130792989467 0.6766015631567173 0.8096009609048171 0.954149894945619 1.0 14.86824114067678 SGRS(ph)PTGNTPPVIDSVSEK ddPTM_PC-9_Lapatinib_30min_R1 1 SGRSPTGNTPPVIDSVSEK 19 1 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 S(0.006)GRS(0.986)PT(0.008)GNTPPVIDSVSEK 197.28 1.0219999999999998e-58 0.0 12028.0 8070.5 7847.3 9369.0 8059.8 7238.5 8876.5 7505.1 9156.3 7192.7 True False 11856.47851433495 8051.813253100041 7202.12528545399 10058.02751406779 7585.738410176479 6928.926228767649 9336.08173695193 7853.814344714573 8125.021073886502 8435.948611329692 1.405470689853587 0.9544644738928653 0.8537421951316008 1.1922817429873394 0.8992158155146466 0.821357093079245 1.106702063643837 0.9309936210572338 0.9631425519797967 1.0 13.04233459145732 -4.760378020579784 24.967415786551722 0.9678121995348066 1.4054712172299288 0.6059545502938389 0.10556284387389701 17.510772913962334 411728.05390758713 0.025748428864753672 0.15316790592797244 1.736288862363588e-05 4.760378020579784 0.4376590176951223 SGS(ph)AAQAEGLCK ddPTM_PC-9_AZD4547_30min_R2 4 SGSAAQAEGLCK 12 0 F8WF93;H7BZZ2;F8WE30;H7C0X4;Q92685 F8WF93 ALG3 Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase 1 S(0.08)GS(0.92)AAQAEGLCK;S(0.085)GS(0.915)AAQAEGLCK;S(0.001)GS(0.999)AAQAEGLCK;S(0.008)GS(0.992)AAQAEGLCK 128.71 0.00019685 231982000.0 251417.0 261190.0 344578.0 325881.0 286803.0 182407.0 309740.0 277350.0 262467.0 220753.0 True False 331362.37620153243 345614.5596511668 340008.6705767344 250754.17026126044 246985.35403013873 171001.06145455845 337306.25995411153 234491.9303689649 276340.46978299937 213024.50466198355 1.5555129524996263 1.6224169148970462 1.5961012143473488 1.17711420411067 1.159422266569954 0.8027295344537674 1.5834152999878204 1.1007744425508454 1.2972238579851758 1.0 17.700659870713714 -5.764545112484908 8.040237239859247 1.166540085930079 1.5953732641213678 0.5217586439510791 0.18913235126636282 0.09242227095658874 47.53857591170967 0.05175144249369619 0.08240891733752355 1.7197086966426113e-06 5.764545112484908 0.42883317819128886 SGS(ph)AAQAEGLCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SGSAAQAEGLCK 12 0 F8WF93;H7BZZ2;F8WE30;H7C0X4;Q92685 F8WF93 ALG3 Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase 1 S(0.188)GS(0.812)AAQAEGLCK;S(0.025)GS(0.975)AAQAEGLCK;S(0.235)GS(0.765)AAQAEGLCK 90.853 0.006722499999999999 156333000.0 149581.0 162786.0 123232.0 152426.0 188505.0 119377.0 147152.0 146872.0 127680.0 125132.0 True False 174902.10894058328 178946.3182648055 126170.31823996277 143886.06539175933 151568.79844446474 113116.6599688021 133212.69727177816 143016.76562374723 129547.0784531715 147817.44105563304 1.1832305287625469 1.2105900155412426 0.8535550158284563 0.9734038443921236 1.0253783136958772 0.7652456919899536 0.9011974251512161 0.9675229431817927 0.8763991415898936 1.0 17.173456978291412 -5.2549508155771 24.993824424232834 0.9186019752637159 1.1969103093330293 0.6952696210067038 0.07323309784514295 272.98411055305434 1051521.9979996919 0.018835318953261997 0.04736652486261278 5.559672177258743e-06 5.2549508155771 0.27830833406931343 SGS(ph)AAQAEGLCK ddPTM_PC-9_Lapatinib_30min_R1 4 SGSAAQAEGLCK 12 0 F8WF93;H7BZZ2;F8WE30;H7C0X4;Q92685 F8WF93 ALG3 Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase 1 S(0.055)GS(0.945)AAQAEGLCK;S(0.179)GS(0.821)AAQAEGLCK;S(0.311)GS(0.689)AAQAEGLCK;S(0.198)GS(0.802)AAQAEGLCK 122.96 0.00037689 228705000.0 428104.0 510035.0 261956.0 161543.0 175820.0 196003.0 203242.0 167698.0 312689.0 90387.0 True False 421999.15845534235 508854.04529395705 240418.98885940207 173423.41111165055 165478.61327541986 187620.4085953089 213764.87628925664 175489.86129164757 277470.6720588554 106010.27251689322 3.9807383608800255 4.80004468635687 2.267883886640233 1.635911379097858 1.5609677189448794 1.7698323392708073 2.0164543606393637 1.6554043030469756 2.617394196535427 1.0 16.693844544801827 -5.353347069809137 4.387693984602463 1.7949610263768658 4.387917270007163 0.8523640809780741 0.43167403611817734 0.06845230726479865 2.2789847205698197 0.10860000148332728 0.24232725959705564 4.432542722556498e-06 5.353347069809137 2.5929562436302973 SGS(ph)DAGEARPPTPASPR ddPTM_PC-9_AZD4547_30min_R2 1 SGSDAGEARPPTPASPR 17 1 Q96FS4;F6RY50;E9PIB3 Q96FS4 SIPA1 Signal-induced proliferation-associated protein 1 1 S(0.018)GS(0.982)DAGEARPPTPASPR 164.82 0.00013395 5518000.0 9986.3 10723.0 14465.0 15881.0 16107.0 15361.0 14205.0 14456.0 12961.0 12675.0 True False 13161.735672056238 14189.000050306155 14273.1846487369 12219.880809004131 13870.821077057946 14400.474241687378 15469.217481268674 12222.157365832887 13646.091999594077 12231.252107969738 1.0760742690832288 1.1600611225289659 1.1669438682763038 0.99907030785849 1.1340475165269372 1.1773507826156409 1.2647288556164349 0.9992564340873226 1.1156741664005474 1.0 13.57828447903983 SGS(ph)DAGEARPPTPASPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSDAGEARPPTPASPR 17 1 Q96FS4;F6RY50;E9PIB3 Q96FS4 SIPA1 Signal-induced proliferation-associated protein 1 1 S(0.145)GS(0.855)DAGEARPPTPASPR 111.11 0.0016795000000000002 2941800.0 6082.0 6031.4 6014.2 6966.9 8835.9 7278.5 8611.4 5335.9 6646.5 4814.7 True False 7111.56247502441 6630.1575318660425 6157.601336980513 6576.567179994555 7104.568824038878 6896.802646933042 7795.665850863006 5195.838278853375 6743.692488557363 5687.56699685577 1.2503698820525295 1.1657282517342407 1.0826424269612278 1.156305883276671 1.2491402436167278 1.2126103570728515 1.3706503774237113 0.9135432218602023 1.1856902067765434 1.0 12.47359591922778 -7.770333722295814 24.999998273033267 1.0372125900369873 1.2049526772671135 0.4297033713326823 0.09440291225260605 203.70021577109122 572545.6524315041 0.05059673455994224 0.024869211181942238 1.6969391825664602e-08 7.770333722295814 0.16774008723012623 SGS(ph)DAGEARPPTPASPR ddPTM_PC-9_Lapatinib_30min_R1 2 SGSDAGEARPPTPASPR 17 1 Q96FS4;F6RY50;E9PIB3 Q96FS4 SIPA1 Signal-induced proliferation-associated protein 1 1 S(0.209)GS(0.791)DAGEARPPTPASPR;S(0.001)GS(0.999)DAGEARPPTPASPR 101.67 0.012996 9335000.0 34390.7 25890.4 32478.7 31756.1 35301.1 38000.0 33418.8 36517.6 32059.5 30220.7 True False 33900.28231151801 25830.452369501425 29808.426657407592 34091.54952924411 33224.75870263292 36374.82858232651 35149.06194455579 38214.341010053016 28448.621508498443 35444.30772844846 0.9564379863542607 0.7287616552535818 0.8409933376546843 0.9618342609603687 0.937379253029279 1.0262530407141002 0.9916701495158361 1.078151710644958 0.8026287810853445 1.0 15.113266332223427 -5.772321063791541 4.323698978824232 0.9775114527027954 0.828469330700508 0.32497831834276236 0.08469544880090252 0.2038941817346183 8.92826326119544 0.022967638165464942 0.03772949229679575 1.689191689873826e-06 5.772321063791541 -0.1490421220022874 SGS(ph)ESSVDQK ddPTM_PC-9_AZD4547_30min_R2 2 SGSESSVDQK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.006)GS(0.994)ESSVDQK;S(0.032)GS(0.967)ES(0.001)SVDQK 146.16 0.00014122 11265100.0 101882.0 66642.0 64586.0 81077.0 63129.0 69461.0 50732.0 57419.0 87402.0 115478.0 True False 134278.35672275367 88182.72324466116 63729.54744025728 62385.95027716321 54364.62803585967 65117.59268939834 55247.04971909349 48546.2129073574 92021.89128528052 111435.15036876764 1.204991030912526 0.7913366918144031 0.5718980701274219 0.5598408587479984 0.4878588834488319 0.5843541510367908 0.4957775848667746 0.4356454201991514 0.8257887298644669 1.0 16.76584485310984 -4.793512846971443 2.1776674663274607 0.5871319967855257 1.3606782555122814 0.5293045721961698 0.16451769994977894 0.438005950417704 2.456383788511771 0.04078713292538422 0.6643315281344692 1.608744788511298e-05 4.793512846971443 0.7735462587267556 SGS(ph)ESSVDQK ddPTM_PC-9_Lapatinib_30min_R1 2 SGSESSVDQK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.009)GS(0.99)ES(0.001)SVDQK;S(0.336)GS(0.664)ESSVDQK 139.76 0.00012173 11988600.0 34375.0 58118.0 33994.0 55033.0 89712.0 57115.0 148221.0 124192.0 98899.0 106658.0 True False 33884.80619639704 57983.43134175927 31199.144540634723 59080.31040470625 84435.31654057819 54672.324591567856 155895.1581290772 129962.4137051864 87759.95316736025 125093.69318714828 0.2708754161227231 0.46352002138918624 0.24940621501963955 0.47228848153294406 0.6749766066484062 0.43705100711811673 1.2462271610755622 1.0389205913902806 0.7015537788629013 1.0 16.932649529831934 -7.244804858385013 24.6504915370096 0.9999187512895017 0.43475197681573885 0.7401409825782723 0.16503605745301425 357.30267390684617 529483.1120086074 0.06557044502142036 0.05063978351226158 5.6910859106368654e-08 7.244804858385013 -0.5651667744737628 SGS(ph)FDSR ddPTM_PC-9_AZD4547_30min_R2 1 SGSFDSR 7 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 S(0.145)GS(0.855)FDSR 82.75 0.022022999999999997 19920000.0 96864.0 80591.0 150090.0 212330.0 172720.0 128040.0 107160.0 122190.0 114690.0 144570.0 True False 127664.73710363744 106640.46470709915 148099.70853293632 163380.59896579868 148740.80936421728 120033.63855905566 116697.03240357262 103308.3431468676 120752.2792557244 139508.64830368318 0.915102673962808 0.7644003866696752 1.0615808434366885 1.171114486108065 1.0661762634273215 0.8604028497055307 0.8364860087350706 0.740515691342557 0.8655540765678568 1.0 17.089995033610272 -6.860047374838036 6.779605755370285 0.8407503950982376 0.9958559601940878 0.24372706366103092 0.11672306242459331 0.3211566560423168 19.018850972487186 0.04557754544327069 0.04024605118229053 1.380233694155878e-07 6.860047374838036 0.15510556509585027 SGS(ph)FDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSFDSR 7 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 S(0.132)GS(0.849)FDS(0.02)R 76.47800000000001 0.031198000000000004 15027000.0 74765.0 81571.0 142640.0 99250.0 126290.0 119340.0 83235.0 104370.0 101680.0 78868.0 True False 87421.23782393934 89668.82979604148 146041.07856521246 93689.34427284144 101544.38108035034 113081.6003139368 75350.37823078498 101630.39808915576 103166.87764033875 93166.14408125564 0.9383369751537015 0.9624615323548869 1.5675337860697713 1.0056157759532205 1.089927914069166 1.2137628043864488 0.8087742492065305 1.0908511787341757 1.1073430016633605 1.0 16.50751816447469 SGS(ph)FDSR ddPTM_PC-9_Lapatinib_30min_R1 1 SGSFDSR 7 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 S(0.004)GS(0.996)FDSR 90.709 0.015746 20104000.0 118530.0 160550.0 128470.0 113470.0 141080.0 112870.0 145170.0 148250.0 130380.0 100710.0 True False 116839.74046426035 160178.25633916273 117907.69250854118 121814.96232482378 132781.951773952 108042.81321282081 152686.1922777346 155138.23621323353 115695.23143773392 118117.58931236005 0.989181553267901 1.3560914785991265 0.9982229843578689 1.0313024760663383 1.1241505397033822 0.9147055391310378 1.2926626183841126 1.313421964640448 0.9794919800791037 1.0 16.84986429204406 -7.279696190559535 24.957131937235467 1.1725126098950898 1.0795786697209095 0.04675432877898311 0.14968606097056952 2283.2142484199167 3121149.675273816 0.06175946340762204 0.041735903094680095 5.251747162221784e-08 7.279696190559535 -0.09293394017418022 SGS(ph)GEIGSETSDKK ddPTM_PC-9_AZD4547_30min_R2 2 SGSGEIGSETSDKK 14 1 A0A0C4DGH6;A0JNW5 A0A0C4DGH6 UHRF1BP1L UHRF1-binding protein 1-like 1 S(0.142)GS(0.855)GEIGS(0.002)ETSDKK;S(0.012)GS(0.988)GEIGSETSDKK 148.18 0.00031123 10234000.0 27286.0 31992.0 31984.0 36178.0 36534.0 43578.0 38988.0 35343.0 39174.0 42410.0 True False 35962.38041594251 42332.788362342086 31559.871262025645 27837.72104452816 31461.88472274386 40853.06077106002 42457.856470236096 29881.551451344203 41244.65766469396 40925.23880859933 0.8787335508079184 1.0343931909676969 0.7711591228490081 0.6802091290101114 0.768764841419398 0.9982363441328499 1.0374492050933306 0.7301497149740616 1.0078049356679015 1.0 15.320703214745562 -6.762339395154098 24.999781924501896 0.9430324700848168 0.8269744971019718 0.22553782988172444 0.11767207096059083 46.181255807304325 1282749.1245971269 0.043476333836436 0.040579094053667324 1.7284650596427604e-07 6.762339395154098 -0.11605797298284504 SGS(ph)GNFGGGR ddPTM_PC-9_AZD4547_30min_R2 3 SGSGNFGGGR 10 0 F8VZ49;F8W6I7;P09651-2;P09651;A0A2R8Y4L2;H0YH80 F8VZ49;F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 S(0.211)GS(0.789)GNFGGGR;S(0.091)GS(0.909)GNFGGGR;S(0.062)GS(0.938)GNFGGGR 110.98 0.0016618 68665800.0 101535.0 68980.0 126622.0 167790.0 125837.0 105130.0 97478.0 144410.0 128781.0 112354.0 True False 133821.01794080168 91276.43602257942 124942.90954665505 129108.60782965834 108366.70465473054 98556.20448073668 106153.35316009203 122094.75271167154 135588.10074837765 108420.52065789593 1.2342775807455588 0.8418741716855244 1.1523917131969228 1.1908133907329264 0.9995036363703214 0.9090179966181442 0.9790891292160678 1.1261221766027347 1.2505759972893395 1.0 16.726278314611477 -9.860943951881362 0.00406696622172658 0.9033274733178507 1.2171263229186664 0.0 0.13427462955151234 1895365.649062352 1946.1650865013542 76432.42979601625 73733.88212752249 1.3773872169060266e-10 9.860943951881362 0.3137988496008157 SGS(ph)GNFGGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSGNFGGGR 10 0 F8VZ49;F8W6I7;P09651-2;P09651;A0A2R8Y4L2;H0YH80 F8VZ49;F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 SGS(1)GNFGGGR 100.02 0.0041482 7979100.0 21529.0 21334.0 21313.0 19520.0 26642.0 23297.0 22866.0 26582.0 18769.0 18822.0 True False 25173.434482867557 23451.898528505848 21821.182750002616 18426.35768469386 21421.691351197234 22075.264307975427 20699.966944496067 25884.250665957094 19043.461117540523 22234.279605129967 1.1321902454199353 1.0547631380463052 0.9814207223052084 0.8287364381458291 0.9634533581315021 0.992848192071946 0.9309933720416155 1.1641596276402404 0.8564910334736796 1.0 14.440498041403556 -5.042764071459071 2.6007009382339863 0.9655297872240597 1.1302693727456397 0.286222384614483 0.08571836240028817 0.41766727541365833 5.054643759068772 0.022702000996798682 0.11618268343541613 9.062247697674665e-06 5.042764071459071 0.16473958552157997 SGS(ph)GNFGGGR ddPTM_PC-9_Lapatinib_30min_R1 4 SGSGNFGGGR 10 0 F8VZ49;F8W6I7;P09651-2;P09651;A0A2R8Y4L2;H0YH80 F8VZ49;F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 1 S(0.219)GS(0.781)GNFGGGR;S(0.444)GS(0.556)GNFGGGR;S(0.002)GS(0.998)GNFGGGR;S(0.084)GS(0.916)GNFGGGR 97.779 0.0050136 61336000.0 91822.0 71092.0 94838.0 79537.0 101541.0 107634.0 99031.0 89561.0 108421.0 117812.0 True False 90512.60144190743 70927.39084187936 87040.78572526693 85386.41630765393 95568.55801728691 103030.74472710867 104158.34061759565 93722.33101850488 96209.48525625507 138175.64722537744 0.6550546587581594 0.5133132521260431 0.6299285545107326 0.6179556095610732 0.6916454522655908 0.7456505310161917 0.753811128872106 0.6782840022861262 0.696283948642038 1.0 17.076143844699438 -14.522878745217009 0.11306543934995887 2.0824839153399104 0.4818142067361977 0.8081515873076957 0.05256342449217743 71.3557991192565 0.5303877410701218 17.796178526209246 0.6457996910022822 3.0000000004374615e-15 14.522878745217009 -1.6006697086037127 SGS(ph)GSESEPSSR ddPTM_PC-9_AZD4547_30min_R2 1 SGSGSESEPSSR 12 0 O14641;I3L2N2;I3L0Z8 O14641 DVL2 Segment polarity protein dishevelled homolog DVL-2 1 S(0.494)GS(0.505)GS(0.001)ESEPSSR 124.47 0.00032148 7744900.0 3514.4 3175.2 4875.5 7364.9 4618.2 5478.1 3682.9 4886.6 4669.5 4726.0 True False 4631.906095938884 4201.5213055797885 4810.847684404892 5667.036091570718 3977.042645934628 5135.553541005644 4010.6709652773284 4131.488252897 4916.320237026815 4560.544178482448 1.0156476759490976 0.9212763085167335 1.0548845699386984 1.242622781357742 0.8720544062919299 1.1260834979378567 0.8794281577625034 0.9059200155082767 1.0780117557512083 1.0 12.154990266235613 -7.266693362793169 24.968064751376495 0.957999991617392 1.0358429894404728 0.09652303144749275 0.10801693281846476 1067.9192792348365 5074955.826029128 0.044307045933944196 0.030908440261865976 5.411362618223706e-08 7.266693362793169 0.0778429978230808 SGS(ph)GSESTGAEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SGSGSESTGAEER 13 0 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 S(0.011)GS(0.856)GS(0.132)EST(0.001)GAEER;S(0.003)GS(0.99)GS(0.003)ES(0.003)T(0.001)GAEER;S(0.269)GS(0.674)GS(0.004)ES(0.005)T(0.047)GAEER 135.91 5.3018e-05 10549600.0 5182.28 6885.3 6113.2 7990.9 8716.5 8461.98 9261.8 10471.3 8430.2 5901.49 True False 6059.53764930442 7568.827080637545 6258.961872440107 7543.195779847344 7008.564396918806 8018.218872335576 8384.455254374785 10196.439470259445 8553.47572662849 6971.383420830865 0.8692016036871818 1.0856994406621627 0.8978077226018003 1.0820227958353106 1.0053333712756125 1.1501617954876373 1.2026960429864733 1.462613495019072 1.2269409398814946 1.0 12.767229261606229 -6.936553772473334 1.7958634077065732 1.2641403092425754 0.9860203932617577 0.43990874486841436 0.12394282756146976 0.29018136460942245 1.9054454477333929 0.05344585067240878 0.04282966571918141 1.1573007312260176e-07 6.936553772473334 -0.27811991598081764 SGS(ph)GSESTGAEER ddPTM_PC-9_Lapatinib_30min_R1 3 SGSGSESTGAEER 13 0 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 S(0.087)GS(0.763)GS(0.008)ES(0.025)T(0.116)GAEER;S(0.195)GS(0.748)GS(0.039)ES(0.001)T(0.018)GAEER;S(0.051)GS(0.536)GS(0.013)ES(0.018)T(0.382)GAEER 98.337 0.0027844000000000002 1466100.0 4846.8 5482.780000000001 5838.95 4258.820000000001 5435.0 7304.1 7288.1 7606.599999999999 4340.1 5995.98 True False 4777.683743205736 5470.084959770998 5358.8940699988 4572.027829807048 5115.323985621128 6991.720669688712 7665.442157052819 7960.030405258546 3851.272234720885 7032.377153858853 0.6793838894980333 0.7778429455777149 0.7620316647917883 0.6501397365040716 0.7273961384187441 0.9942186712571537 1.0900214805525024 1.1319117605759619 0.5476487040527384 1.0 12.779796730486229 -6.75695420216014 24.209111794921558 0.9695834670057598 0.7211331260777954 0.36730488090433433 0.15235740276862872 80.72418483915652 435714.97023837274 0.05075261013013893 0.049074579208697955 1.7500312256781776e-07 6.75695420216014 -0.24845034092796436 SGS(ph)ISVK ddPTM_PC-9_AZD4547_30min_R2 1 SGSISVK 7 0 Q8TF01 Q8TF01 PNISR Arginine/serine-rich protein PNISR 1 S(0.001)GS(0.994)IS(0.004)VK 98.58200000000001 0.012116 44087000.0 268960.0 226550.0 356450.0 455740.0 454490.0 383000.0 343110.0 371560.0 348270.0 436230.0 True False 354483.6852844647 299777.85707328696 351723.24009970744 350676.18411281036 391391.90856845275 359050.9494542205 373646.1253078557 314143.9395993957 366678.8411927037 420957.7204780772 0.8420885709896978 0.712132935186062 0.8355310355164863 0.8330437168714976 0.9297653648541073 0.8529382690652404 0.8876096271224336 0.7462600739157979 0.8710585965171762 1.0 18.683315815757837 -14.522878745280336 0.2030910813257039 1.7456784944442272 0.8085378356030481 0.4163025086997493 0.05969335614972343 153.21217665461887 1.5157406755695015 46.64017006651168 0.14549844307746704 3.0000000000000132e-15 14.522878745280336 -0.937140658841179 SGS(ph)ISVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGSISVK 7 0 Q8TF01 Q8TF01 PNISR Arginine/serine-rich protein PNISR 1 S(0.077)GS(0.922)IS(0.001)VK;S(0.002)GS(0.997)IS(0.001)VK 78.264 0.028586 51823000.0 238560.0 202179.0 159236.0 263300.0 236200.0 235564.0 222176.0 252940.0 213628.0 153408.0 True False 278943.4962252257 222249.99496553736 163032.7901458933 248548.1546301175 189918.3055758873 223210.60915327846 201129.88086505546 246300.59301208315 216751.90535552992 181219.65602293995 1.539256294526435 1.226412188628167 0.8996418695621823 1.3715297781972098 1.0480005852778256 1.2317130164126513 1.1098679099114677 1.3591273618845454 1.1960728218581989 1.0 17.46737992048793 -4.7856580381300535 4.50233005861056 1.1642468236504375 1.562128347696283 0.3974879704822393 0.14163907077967006 0.18340211496248118 7.964587735161036 0.03368013834908047 0.22444621844222393 1.6381058522478355e-05 4.7856580381300535 0.39788152404584554 SGS(ph)ISVK ddPTM_PC-9_Lapatinib_30min_R1 2 SGSISVK 7 0 Q8TF01 Q8TF01 PNISR Arginine/serine-rich protein PNISR 1 S(0.001)GS(0.956)IS(0.043)VK;S(0.032)GS(0.959)IS(0.009)VK 83.647 0.020712 78590000.0 473960.0 389840.0 389480.0 417520.0 480440.0 461520.0 463580.0 416850.0 452160.0 398460.0 True False 467201.2434863806 388937.3494316982 357458.45783627685 448225.8136058891 452181.4637813822 441781.8654556666 487581.9040856396 436218.3727857428 401232.9793441153 467333.2800854243 0.9997174680155037 0.8322483461066671 0.76488979721482 0.9591138331170369 0.9675781354555522 0.9453250694555989 1.0433280163495182 0.9334203048967666 0.8585585414990636 1.0 18.83409225357103 -5.87913819875559 24.999134890373405 0.9588252169728364 0.8622166847561963 0.26791331281934805 0.07005069859815699 8.732801340841167 1832.8676298431437 0.020084372352392174 0.02978994074859874 1.3208752457867653e-06 5.87913819875559 -0.09660853221664012 SGS(ph)LKGPDDPR ddPTM_PC-9_AZD4547_30min_R2 1 SGSLKGPDDPR 11 1 A8MVZ6;Q96G01-4;Q96G01-3;Q96G01 A8MVZ6 BICD1 Protein bicaudal D homolog 1 1 S(0.201)GS(0.799)LKGPDDPR 58.781000000000006 0.033319999999999995 29582000.0 293320.0 236140.0 235590.0 307380.0 302040.0 249860.0 264190.0 236410.0 271240.0 271740.0 True False 386589.65856498753 312467.63703061576 232465.9226682285 236518.28997365944 260106.9595899043 234236.2147013877 287702.39819615416 199878.26666135524 285577.19265256537 262226.4653112192 1.4742587408413177 1.1915945885163368 0.8865082416160021 0.9019619346695291 0.9919172699872248 0.8932592460619422 1.0971524092913323 0.7622352931620878 1.0890479430199111 1.0 18.000453771920398 -4.939600975024793 2.6402826983598766 0.9473898591263862 1.5006737249924733 0.7426409732886228 0.09641344792722868 0.1546492977983527 1.8159496738888712 0.023431777098143414 0.16380410571425547 1.149209017136976e-05 4.939600975024793 0.5532838658660871 SGS(ph)LKGPDDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSLKGPDDPR 11 1 A8MVZ6;Q96G01-4;Q96G01-3;Q96G01 A8MVZ6 BICD1 Protein bicaudal D homolog 1 1 S(0.293)GS(0.707)LKGPDDPR 53.448 0.044442 16836000.0 225700.0 217090.0 159230.0 235250.0 207470.0 172240.0 213800.0 213600.0 171460.0 146320.0 True False 263906.5522218032 238641.26050217132 163026.64708313753 222069.70519079044 166817.74283585622 163207.43118880905 193547.31622204455 207993.22632790715 173967.2781295484 172846.65773151693 1.5268247340468095 1.3806530229404452 0.9431865748678067 1.2847787056185476 0.9651198641918467 0.9442324967736402 1.1197631401278352 1.203339590465113 1.006483321186182 1.0 17.399133181474873 -5.09797165957495 4.264650089223913 1.0692706801189182 1.4998656118116942 0.6809949222323278 0.10980114197862834 0.12032079740164676 3.6835455207522108 0.02819867448486481 0.08745429601377797 7.980467631001254e-06 5.09797165957495 0.43059493169277596 SGS(ph)LRRSS(ph)MS(ph)LYTAASVIDT(ph)ASK ddPTM_PC-9_AZD4547_30min_R2 1 SGSLRRSSMSLYTAASVIDTASK 23 2 Q96PE2;A0A2R8Y4D7 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 4 S(0.373)GS(0.403)LRRS(0.407)S(0.699)MS(0.547)LY(0.273)T(0.288)AAS(0.334)VIDT(0.582)AS(0.095)K 40.158 0.03683 11615000.0 15875.0 28556.0 27230.0 12480.0 18256.0 24113.0 28314.0 32775.0 27538.0 20096.0 True False 20922.919779487172 37786.16855698427 26868.912408234064 9602.928814077926 15721.469521498097 22605.210298145168 30833.891148514016 27710.376844574763 28993.602460058755 19392.44515674636 1.0789211783439483 1.9484994414868304 1.3855350468214034 0.49518916962037673 0.8107007339416824 1.1656709669889738 1.5899950160636314 1.4289263999766793 1.4950978190582784 1.0 14.243207101153393 -7.162894899614049 8.597397801300021 1.4138533225703829 1.1487334506713707 0.0783204147708888 0.38094760609492895 0.9323260554434605 74.08206961962692 0.1614388879708471 0.12499416786068171 6.872347324714888e-08 7.162894899614049 -0.2651198718990122 SGS(ph)MDNTSAR ddPTM_PC-9_AZD4547_30min_R2 1 SGSMDNTSAR 10 0 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 S(0.217)GS(0.622)MDNT(0.156)S(0.005)AR 90.697 0.0085448 11205000.0 10750.0 11576.0 10332.0 18539.0 13862.0 15503.0 14372.0 17283.0 15089.0 12314.0 True False 14168.276386109428 15317.715618982003 10194.990929191123 14265.119974694773 11937.500575537179 14533.594959239597 15651.080157746821 14612.30947383023 15886.57373519597 11882.890608089894 1.1923257440797814 1.2890563520422946 0.8579554643253514 1.2004755783060943 1.0045956803986822 1.2230689853649834 1.3171105140942336 1.2296931744774409 1.3369283837705583 1.0 13.536598205476853 -6.929827131956625 10.393787653248566 1.2443470076523462 1.1101800936957735 0.13086592410895215 0.1398037850972337 0.7466113545437297 105.84724881630939 0.04778710540489982 0.04214466349299291 1.1753653082200079e-07 6.929827131956625 -0.13416691395657265 SGS(ph)MDNTSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGSMDNTSAR 10 0 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 S(0.158)GS(0.814)MDNT(0.004)S(0.024)AR;S(0.017)GS(0.983)MDNTSAR 72.29 0.030945999999999998 21838000.0 35574.0 41247.0 37658.0 37706.0 47264.0 39703.0 40172.0 44972.0 40547.0 29587.0 True False 41595.9755814729 45341.729568073504 38555.90953876028 35593.45506450139 38002.95848746289 37620.90478686302 36366.61733990627 43791.53265177271 41139.923167612345 34950.88888943686 1.1901264003057839 1.2972983236994882 1.1031453208737407 1.018384830700507 1.0873245200624484 1.0763933617217134 1.0405062215999115 1.252944747422654 1.177078022185753 1.0 15.093041526997801 -5.277909503037848 22.544532659637007 1.0979601347947798 1.2437123295175598 0.3888444857567567 0.07473772950131621 211.42123754554328 289397.4685662359 0.020575051463909394 0.043114272641694894 5.2733973542367225e-06 5.277909503037848 0.14575219472278 SGS(ph)MDNTSAR ddPTM_PC-9_Lapatinib_30min_R1 1 SGSMDNTSAR 10 0 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 S(0.308)GS(0.681)MDNT(0.009)S(0.002)AR 91.09299999999999 0.0082915 12374000.0 14546.0 14025.0 16085.0 13156.0 14592.0 14902.0 15067.0 13933.0 17788.0 12983.0 True False 14338.571372590293 13992.525974193424 14762.553389895564 14123.536127129466 13733.727248975794 14264.67619825868 15847.095536602808 14580.37804491721 15784.52812405592 15227.094251239929 0.9416485598637913 0.9189229240538802 0.9694924813835353 0.9275266767314715 0.9019269876691982 0.9367956855653612 1.0407169795584863 0.9575285871583767 1.0366080266936417 1.0 13.894353041710458 -7.192166119057599 8.229492660325894 1.0050902251134706 0.9319395631980969 0.6584292692807656 0.02676497133686437 0.21084508048186038 23.217240788598186 0.009883469996648417 0.007643362226148534 6.424419341757515e-08 7.192166119057599 -0.07315066191537367 SGS(ph)MDPSGAHPSVR ddPTM_PC-9_AZD4547_30min_R2 7 SGSMDPSGAHPSVR 14 0 Q07666;Q07666-3;Q07666-2 Q07666 KHDRBS1 KH domain-containing, RNA-binding, signal transduction-associated protein 1 1 S(0.425)GS(0.575)MDPSGAHPS(0.001)VR;S(0.169)GS(0.831)MDPSGAHPSVR;S(0.201)GS(0.754)MDPS(0.043)GAHPS(0.002)VR;S(0.466)GS(0.533)MDPSGAHPSVR;S(0.002)GS(0.997)MDPS(0.001)GAHPSVR;S(0.455)GS(0.545)MDPSGAHPSVR;S(0.053)GS(0.947)MDPSGAHPSVR 114.06 0.00010139 59008900.0 36717.75 45952.29 213392.5 620105.0 355268.0 257893.1 115264.0 388993.0 146928.6 260979.0 True False 48393.23072335533 60805.469096491914 210562.77602181755 477149.3727767458 305945.17057206266 241767.0036884907 125522.27270404482 328883.0700198836 154694.9458353181 251842.20464582523 0.19215695316602105 0.24144272871977449 0.8360901077638657 1.8946362602240485 1.2148288290373108 0.9599939931771815 0.4984163511456363 1.3059092715710765 0.6142534610228304 1.0 17.94216054991231 -5.33135927034908 4.089825350715688 1.0774612248917275 0.20736383321468208 0.45741008395097016 0.3640549345707004 0.19270943389728198 6.2432384719648955 0.10169659415861164 0.23543003259284595 4.6627349571882115e-06 5.33135927034908 -0.8700973916770454 SGS(ph)MDPSGAHPSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSMDPSGAHPSVR 14 0 Q07666;Q07666-3;Q07666-2 Q07666 KHDRBS1 KH domain-containing, RNA-binding, signal transduction-associated protein 1 1 S(0.064)GS(0.936)MDPS(0.001)GAHPSVR 104.9 0.00089997 6365700.0 2637.5 2416.5 8843.6 9628.1 15528.0 15503.0 9429.7 8488.2 12190.0 5406.6 True False 3083.9766570004713 2656.3941499078637 9054.46496353977 9088.668771721364 12485.399868680683 14689.995388528261 8536.450550884048 8265.393743991313 12368.255688785715 6386.773781377945 0.48286924863261776 0.41592112713513824 1.417689943855546 1.423045356361516 1.9548836855760625 2.3000650862819345 1.3365825756619034 1.2941422425342355 1.9365420026067162 1.0 12.640871636024551 -5.340917001126831 2.6484123498039365 1.6478005508758145 0.40333941009937596 0.6105105620118603 0.3624187204587072 0.18427581325750103 2.4761262164741304 0.1024036446587684 0.28690970621990036 4.561240783924546e-06 5.340917001126831 -1.2444611407764385 SGS(ph)MDPSGAHPSVR ddPTM_PC-9_Lapatinib_30min_R1 2 SGSMDPSGAHPSVR 14 0 Q07666;Q07666-3;Q07666-2 Q07666 KHDRBS1 KH domain-containing, RNA-binding, signal transduction-associated protein 1 1 S(0.001)GS(0.999)MDPSGAHPSVR;S(0.285)GS(0.713)MDPS(0.001)GAHPSVR 113.52 0.00017688 7251000.0 8525.7 6367.5 30148.0 8520.9 17375.6 27876.0 15551.4 14443.7 36834.0 10085.7 True False 8404.121954578106 6352.75644496803 27669.34781464543 9147.555410889132 16353.601369743968 26683.808462129844 16356.575398415393 15114.807031319226 32685.367040784557 11828.999806649497 0.7104676719881129 0.5370493320489297 2.339111359110135 0.7733160504193236 1.3825007724280318 2.2557958321319727 1.3827521908674634 1.2777755751439492 2.763155598532596 1.0 13.530040472247451 -5.235684598292948 24.511664550881747 1.6284058276426632 0.6237580491071998 0.318870679897335 0.5975988608808931 695.628010314016 662048.57109145 0.14631981423516324 0.38679525493094563 5.81186344638809e-06 5.235684598292948 -1.0046477785354635 SGS(ph)NGSVVSLEQQQK ddPTM_PC-9_AZD4547_30min_R2 3 SGSNGSVVSLEQQQK 15 0 Q2M1P5 Q2M1P5 KIF7 Kinesin-like protein KIF7 1 S(0.037)GS(0.963)NGSVVSLEQQQK;S(0.053)GS(0.891)NGS(0.039)VVS(0.016)LEQQQK;S(0.007)GS(0.992)NGSVVSLEQQQK 226.74 2.2035000000000003e-24 55530000.0 104247.0 101702.0 119098.0 137209.0 134361.0 123531.0 115486.0 120536.0 115558.0 118889.0 True False 137395.37752769754 134575.18260899355 117518.68270274908 105577.58490791825 115707.29438968076 115806.58704185174 125764.03027397377 101909.93084172907 121666.1599636673 114726.73229699506 1.1975881712731062 1.1730063248085587 1.0243356569986362 0.9202526978159523 1.008546936472899 1.0094124074070308 1.0962051106659803 0.8882840886456443 1.0604865799603533 1.0 16.80784206508254 -5.272930840733492 3.841400843800482 0.9964066670907447 1.1915808847845648 0.6323397617400084 0.056615990146697694 0.12673840205167367 4.275954857629454 0.01457765582037295 0.037755599890941176 5.334198332170869e-06 5.272930840733492 0.19517421769382015 SGS(ph)NGSVVSLEQQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SGSNGSVVSLEQQQK 15 0 Q2M1P5 Q2M1P5 KIF7 Kinesin-like protein KIF7 1 S(0.286)GS(0.711)NGS(0.003)VVSLEQQQK;S(0.243)GS(0.757)NGSVVSLEQQQK;S(0.01)GS(0.989)NGS(0.001)VVSLEQQQK 149.19 9.8165e-10 35825000.0 95958.0 109321.0 87288.0 107533.0 111333.0 98088.0 113059.0 94809.0 84134.0 77171.0 True False 112201.79414310963 120173.66640268039 89369.27696158325 101508.27463668986 89518.09786062768 92944.0926059448 102349.23304372333 92320.36420843926 85364.30058410951 91161.49141470021 1.2308025285884756 1.3182503328735782 0.9803402245256821 1.1134994948132364 0.9819727219402695 1.019554322374295 1.1227244251427313 1.0127123062134564 0.9364074595465002 1.0 16.4761369070376 -5.261047056778834 24.999999807700096 1.0268605731324074 1.2745264468401436 0.7519599718441058 0.058185587594980166 15.753956685839084 1003801.7444446157 0.014904341827883541 0.03481784696824199 5.482175611032795e-06 5.261047056778834 0.24766587370773618 SGS(ph)NGSVVSLEQQQK ddPTM_PC-9_Lapatinib_30min_R1 3 SGSNGSVVSLEQQQK 15 0 Q2M1P5 Q2M1P5 KIF7 Kinesin-like protein KIF7 1 S(0.02)GS(0.98)NGS(0.001)VVSLEQQQK;S(0.014)GS(0.985)NGSVVSLEQQQK;S(0.002)GS(0.998)NGSVVSLEQQQK 185.63 4.1738999999999995e-07 58907000.0 106811.0 98986.0 87462.0 90756.0 97529.0 94224.0 87351.0 84849.0 88820.0 72710.0 True False 105287.85555326143 98756.80399868182 80271.21197308335 97430.49899314107 91792.5359693915 90194.25916687206 91873.60736827456 88791.39429650344 78816.15628393556 85277.82662001484 1.2346451560311014 1.1580595790594814 0.9412905459089593 1.142506825687253 1.076393942101799 1.057651944728424 1.0773446159416038 1.0412014214684966 0.9242280133982365 1.0 16.379883049770342 -5.043690904816954 5.980352893237579 1.0420099340707347 1.2181565880755694 0.5353646175962103 0.06235964474960253 0.13257453821835644 12.61487192848642 0.015823709975779317 0.046219102266792836 9.042928462057341e-06 5.043690904816954 0.17614665400483465 SGS(ph)NTGLDYIK ddPTM_PC-9_AZD4547_30min_R2 2 SGSNTGLDYIK 11 0 P35367 P35367 HRH1 Histamine H1 receptor 1 S(0.112)GS(0.882)NT(0.006)GLDYIK;S(0.005)GS(0.995)NTGLDYIK 119.87 0.00092273 8052200.0 36655.0 54246.0 49592.0 64417.0 55470.0 38378.0 46212.0 65474.0 41217.0 40662.0 True False 48310.52752863641 71779.9586616532 48934.37767716284 49566.65588272902 47768.94798189633 35978.217593091504 50324.778475493695 55356.49774284327 43395.646473826804 39238.435756549545 1.2312042158962104 1.829327731283782 1.2471031715120011 1.2632169179795993 1.2174019443148394 0.9169126367909848 1.2825378358028368 1.4107722868030832 1.105947411947566 1.0 15.259979909097162 -5.482049059471666 17.016211375747318 1.1895488544444726 1.5322676093821934 0.35535118249550013 0.18971607663839038 13.12947234563485 5470.158165169001 0.048019870550057894 0.0997935504614646 3.2957248037805505e-06 5.482049059471666 0.34271875493772086 SGS(ph)NTGLDYIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSNTGLDYIK 11 0 P35367 P35367 HRH1 Histamine H1 receptor 1 S(0.119)GS(0.88)NTGLDYIK 93.243 0.0072079 2939600.0 22027.0 20399.0 17980.0 17779.0 23001.0 16167.0 15579.0 12971.0 13490.0 12973.0 True False 25755.7360469192 22424.077907705578 18408.711389529715 16782.900270295704 18494.119164060052 15319.174059623068 14103.244337807408 12630.524993910523 13687.265729427345 15324.9022057885 1.6806460296491015 1.463244437490478 1.201228637046467 1.0951391431363582 1.206801773721889 0.9996262197246996 0.920282827806911 0.8241830730338847 0.8931388628540423 1.0 13.90359024709199 -3.0581072797903874 0.38324155948435806 0.8818062006774341 4.593109912888049 0.9135121137167941 0.07520448102126875 5.877038255429965 0.2380576980085467 0.06305932389816855 13.18289831036028 0.0008747676626881832 3.0581072797903874 3.711303712210615 SGS(ph)NTGLDYIK ddPTM_PC-9_Lapatinib_30min_R1 1 SGSNTGLDYIK 11 0 P35367 P35367 HRH1 Histamine H1 receptor 1 S(0.146)GS(0.674)NT(0.18)GLDYIK 96.59100000000001 0.005741 3555600.0 34602.0 36428.0 20159.0 14522.0 19773.0 15797.0 12107.0 14135.0 23885.0 13070.0 True False 34108.56913477034 36343.65320412965 18501.60483599035 15589.996323971876 18609.9910152137 15121.399134605572 12733.841219994036 14791.763702354465 21194.819779799607 15329.132085319714 2.225081560060088 2.3708878625251697 1.2069571018772045 1.0170175478429067 1.2140277030449738 0.9864484858269906 0.8306955115997 0.9649446309175017 1.3826496935268306 1.0 13.90398839542079 -5.30369521838713 4.625503956160598 1.0555359003002176 2.3086636814659465 0.9157599514709069 0.14863106148965075 0.04778783698921579 2.396659411290647 0.040354385390042415 0.09295368696384977 4.969409451050344e-06 5.30369521838713 1.2531277811657289 up SGS(ph)PAPETTNESVPFAQHSSLDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSPAPETTNESVPFAQHSSLDSR 24 0 O15047 O15047 SETD1A Histone-lysine N-methyltransferase SETD1A 1 S(0.449)GS(0.544)PAPET(0.006)TNESVPFAQHSSLDSR 143.04 2.41e-06 7423500.0 8042.3 10954.0 24978.0 21694.0 27578.0 27296.0 20118.0 17874.0 24032.0 10130.0 True False 9403.702547334564 12041.440727536004 25573.5702495925 20478.555512896965 22174.288870329474 25864.549708138275 18212.277398293176 17404.82643906843 24383.422535922753 11966.488810964125 0.7858364049710684 1.006263484448605 2.137098914609027 1.7113253383176006 1.8530321818387192 2.1614151082011834 1.5219399513085605 1.454463937919827 2.0376421957276047 1.0 13.546712280527299 -5.130343427413305 5.440735392721581 1.760047228749631 0.840676270769367 0.5018536667172666 0.335777098193017 0.15988290426234714 6.268093774126839 0.08203425451778842 0.23016452929417242 7.407242664933549e-06 5.130343427413305 -0.9193709579802639 SGS(ph)PAPETTNESVPFAQHSSLDSR ddPTM_PC-9_Lapatinib_30min_R1 1 SGSPAPETTNESVPFAQHSSLDSR 24 0 O15047 O15047 SETD1A Histone-lysine N-methyltransferase SETD1A 1 S(0.047)GS(0.952)PAPETTNESVPFAQHSSLDSR 171.36 9.3618e-11 5391400.0 24864.0 15620.0 51130.0 22485.0 30782.0 40844.0 21168.0 26214.0 60205.0 24933.0 True False 24509.434800500847 15583.832849689936 46926.28876750762 24138.62190776115 28971.463279740492 39097.19733201431 22263.975464180545 27431.998138911935 53424.078913244135 29242.63582886582 0.8381404105955195 0.5329147803532441 1.604721579892125 0.825459854201432 0.99072680894047 1.3369929291196423 0.7613532375971205 0.9380822679408886 1.82692419472353 1.0 14.835785736183414 -5.230169601619857 24.963972007913867 1.132335739675268 0.6855275255870921 0.24360698405583137 0.33183862823175575 971.1437405014234 775301.6889114159 0.08171522066610751 0.21615517525003305 5.886137437541467e-06 5.230169601619857 -0.44680821408817595 SGS(ph)PISSEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGSPISSEER 10 0 H8Y6P7;P0CAP2-3;P0CAP2;P0CAP2-2;P0CAP1-11 H8Y6P7 GCOM1;POLR2M;MYZAP DNA-directed RNA polymerase II subunit GRINL1A;Myocardial zonula adherens protein 1 S(0.008)GS(0.776)PIS(0.164)S(0.051)EER;S(0.017)GS(0.954)PIS(0.027)S(0.002)EER 92.943 0.007109699999999999 51450000.0 32653.0 39877.0 40013.0 43886.0 49252.0 42718.0 40174.0 41594.0 38200.0 32208.0 True False 38180.50797385269 43835.72502208808 40967.06167014751 41427.20970033169 39601.424158440284 40477.79287925887 36368.42788542751 40502.20157248588 38758.6027327001 38047.05544161227 1.003507565321191 1.152145008681663 1.0767472329893264 1.0888414154390125 1.0408538505486549 1.0638876625124607 0.955880224193412 1.0645292021255448 1.0187017702902077 1.0 15.215497183760137 -6.644773967576302 1.5976604011745477 1.0167199201160184 1.085161934018454 0.30101540460165244 0.043861402016123104 0.4508807451232008 2.3771905996607354 0.01749637557680986 0.01745869222710568 2.2658232686279051e-07 6.644773967576302 0.06844201390243554 SGS(ph)PISSEER ddPTM_PC-9_Lapatinib_30min_R1 2 SGSPISSEER 10 0 H8Y6P7;P0CAP2-3;P0CAP2;P0CAP2-2;P0CAP1-11 H8Y6P7 GCOM1;POLR2M;MYZAP DNA-directed RNA polymerase II subunit GRINL1A;Myocardial zonula adherens protein 1 S(0.186)GS(0.795)PIS(0.019)S(0.001)EER;S(0.006)GS(0.766)PIS(0.114)S(0.114)EER 91.31299999999999 0.008151 50000000.0 65603.0 52260.0 63211.0 58184.0 67003.0 59569.0 52188.0 54242.0 56555.0 55160.0 True False 64667.48918988315 52138.99518084481 58014.035581516255 62463.0454561341 63062.01527296641 57021.37273212127 54890.03928215487 56762.28134015645 50185.180349448055 64694.33250392005 0.9995850747198717 0.8059283273026355 0.8967406160037432 0.9655103165698364 0.9747687754432781 0.8813967240278142 0.8484520537997496 0.8773918694766196 0.7757276164246252 1.0 15.981351711139336 -6.983416211616102 24.35215819436749 0.8651396523068227 0.9225972215871073 0.10722616514909578 0.07168064420660616 380.8860837407183 559302.0700972981 0.024894181879056766 0.02194797078795448 1.0389240225793624e-07 6.983416211616102 0.05745756928028467 SGS(ph)PISSEERR ddPTM_PC-9_AZD4547_30min_R2 2 SGSPISSEERR 11 1 H8Y6P7;P0CAP2-3;P0CAP2;P0CAP2-2;P0CAP1-11 H8Y6P7 GCOM1;POLR2M;MYZAP DNA-directed RNA polymerase II subunit GRINL1A;Myocardial zonula adherens protein 1 S(0.177)GS(0.82)PIS(0.001)S(0.001)EERR;S(0.137)GS(0.862)PISSEERR 66.023 0.019819999999999997 18812800.0 25664.0 31651.0 40447.0 83006.0 54384.0 43242.0 34115.0 47329.0 36214.0 38871.0 True False 33824.618155638345 41881.566780960544 39910.646352399686 63870.24912991602 46833.720336171806 40538.0709041759 37151.168910487926 40015.39056222362 38128.198107653734 37510.138121411605 0.9017460305306239 1.1165399243639051 1.0639962514458943 1.7027463061634927 1.2485616604391574 1.0807230507380052 0.990430074937027 1.066788675442972 1.016477145038539 1.0 15.1949929549111 -6.890943091035126 4.533578657670082 1.0255623925264992 1.2205287872149428 0.17410224070250557 0.1934610525010185 0.4159584084077627 14.679756327964876 0.07555989130727263 0.06639204764640652 1.28545509203054e-07 6.890943091035126 0.19496639468844368 SGS(ph)PISSEERR ddPTM_PC-9_Lapatinib_30min_R1 1 SGSPISSEERR 11 1 H8Y6P7;P0CAP2-3;P0CAP2;P0CAP2-2;P0CAP1-11 H8Y6P7 GCOM1;POLR2M;MYZAP DNA-directed RNA polymerase II subunit GRINL1A;Myocardial zonula adherens protein 1 S(0.159)GS(0.841)PISSEERR 84.89200000000001 0.019825 0.0 21958.0 25620.0 27171.0 20914.0 21715.0 21568.0 17597.0 19149.0 22442.0 14920.0 True False 21644.87489339597 25560.678464088094 24937.105263093086 22452.0853270588 20437.76639333261 20645.586917463646 18508.086557217724 20038.732446861388 19914.345635263267 17498.902120349663 1.2369275937731492 1.4607018365091204 1.4250668465705318 1.2830567982290173 1.1679456375474728 1.1798218411345172 1.0576713001722817 1.145142267157328 1.1380340034078287 1.0 14.094976789880594 -6.249439792059917 1.6924577468585391 1.1084884409963793 1.383346021478613 0.7343758048251027 0.07188376710778194 0.1863532611772427 1.0559712401421484 0.02527714733877822 0.03415295621887752 5.630671721846328e-07 6.249439792059917 0.27485758048223374 SGS(ph)PKLDPSEVYLK ddPTM_PC-9_AZD4547_30min_R2 1 SGSPKLDPSEVYLK 14 1 Q5TCQ9-3;Q5TCQ9-2;Q5TCQ9;Q5TCQ9-1 Q5TCQ9-3 MAGI3 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 1 S(0.171)GS(0.823)PKLDPS(0.006)EVYLK 60.196000000000005 0.026764999999999997 13129000.0 187420.0 131180.0 175620.0 309700.0 284440.0 202620.0 180880.0 179560.0 170210.0 216380.0 True False 247015.66142182617 173581.3696352848 173291.16405193048 238303.4498173024 244950.41579178965 189950.1393692268 196977.96958900924 151813.12787831688 179206.95310939813 208804.60206094664 1.182999124462431 0.8313100761285867 0.8299202332779506 1.1412748927236074 1.173108319328578 0.9097028393741219 0.9433602882541574 0.7270583424880891 0.8582519319046932 1.0 17.67179398374566 -7.239999547691318 2.49447414364356 0.8503231782703228 1.0139211471275291 0.19375739986696672 0.13632465804464358 0.48934371177218805 6.001117169084782 0.06625795044425938 0.04475646361626025 5.754405366462109e-08 7.239999547691318 0.16359796885720634 SGS(ph)PLEK ddPTM_PC-9_AZD4547_30min_R2 1 SGSPLEK 7 0 Q9NRA8;Q9NRA8-3;B1AKL4;B1AKL5 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 S(0.001)GS(0.999)PLEK 78.149 0.028754000000000002 4898100.0 49086.0 48160.0 34410.0 40487.0 36791.0 45285.0 55918.0 45108.0 61225.0 43239.0 True False 64694.32694777373 63726.77817986986 33953.700916905414 31153.347667914495 31683.20470888677 42453.321791212344 60894.59367248028 38137.59507872093 64461.2285066852 41725.215770927294 1.550485138362077 1.5272965520353883 0.8137453645132062 0.7466311939271284 0.7593299189350758 1.0174500240881288 1.4594195032278192 0.9140179235524506 1.5448986258232744 1.0 15.34863188967278 SGS(ph)PRPTEPTDFLMLFEGS(ph)PSGK ddPTM_PC-9_Lapatinib_30min_R1 1 SGSPRPTEPTDFLMLFEGSPSGK 23 1 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 2 S(0.385)GS(0.439)PRPT(0.14)EPT(0.037)DFLMLFEGS(0.781)PS(0.218)GK 51.659 0.041306 3466700.0 18013.0 18864.0 17076.0 17167.0 20064.0 17612.0 17240.0 17298.0 18300.0 16830.0 True False 17756.13131682037 18820.3215670007 15672.077195266187 18429.518447433227 18883.87496734173 16858.775815577235 18132.602844032146 18101.72822945366 16238.861292456902 19739.04307543463 0.8995436733667193 0.9534566338944118 0.7939633717487647 0.9336581503471607 0.9566763137997726 0.8540827309181007 0.9186161038676839 0.9170519644886626 0.8226772306235185 1.0 14.268764430955304 -10.720157147838862 5.386482843567677 1.0000049161659539 0.8963730525950264 0.2708005248420594 0.05188921743293864 2.9663987655461213e-06 4.419980148554793e-07 0.0486498753897159 0.011798768159775314 1.904771358836149e-11 10.720157147838862 -0.10363186357092746 SGS(ph)PRPTEPTDFLMLFEGSPSGK ddPTM_PC-9_AZD4547_30min_R2 2 SGSPRPTEPTDFLMLFEGSPSGK 23 1 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 S(0.171)GS(0.717)PRPT(0.056)EPT(0.056)DFLMLFEGSPSGK;S(0.082)GS(0.452)PRPT(0.432)EPT(0.034)DFLMLFEGSPSGK 81.346 0.00021976 37355000.0 118928.0 107915.0 146868.0 207090.0 170240.0 170740.0 131667.0 165459.0 128161.0 147055.0 True False 156744.6301439275 142796.41335715645 144920.43435815355 159348.6000086057 146605.1145563016 160063.60080891268 143385.10792722297 139891.1134195727 134935.32881413272 141906.64921005862 1.1045615622415608 1.0062700666392366 1.0212378007998324 1.1229114413992571 1.0331095503445227 1.127949970631588 1.0104185302478381 0.9857967487661385 0.9508738988995045 1.0 17.114582664664262 -7.490351470916295 6.755225137538555 0.9801279423685268 1.0655640101755497 0.507193505946476 0.04065280184053952 0.17020507318506664 26.24698327894905 0.01761023652254559 0.011413761689133821 3.2333188121207976e-08 7.490351470916295 0.08543606780702284 SGS(ph)PRPTEPTDFLMLFEGSPSGK ddPTM_PC-9_Lapatinib_30min_R1 1 SGSPRPTEPTDFLMLFEGSPSGK 23 1 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 S(0.026)GS(0.474)PRPT(0.25)EPT(0.25)DFLMLFEGSPSGK 99.414 9.7313e-06 10208000.0 57100.0 46917.0 51490.0 44823.0 51050.0 51674.0 44520.0 46842.0 54614.0 39144.0 True False 56285.743529142426 46808.36656907188 47256.69095714782 48119.43294514469 48047.33936816165 49464.0234779774 46825.027761967 49018.450325128266 48462.79620908421 45909.98824389862 1.2260021333510738 1.0195682543066793 1.0293335451556813 1.0481255775869145 1.0465552531381248 1.0774131157515838 1.0199311642862376 1.067707751627289 1.0556046312106138 1.0 15.486520442171035 -4.756926746901145 24.999992474208575 1.0431807534581363 1.2260024061764785 0.8579566742035357 0.022623092037216505 46.69557026409921 258661.43947108393 0.00544734114731198 0.04212465914859341 1.7501418627719475e-05 4.756926746901145 0.18282165271834216 SGS(ph)PSDNSGAEEMEVSLAKPK ddPTM_PC-9_AZD4547_30min_R2 1 SGSPSDNSGAEEMEVSLAKPK 21 1 P31749-2;P31749 P31749-2 AKT1 RAC-alpha serine/threonine-protein kinase 1 S(0.022)GS(0.341)PS(0.318)DNS(0.318)GAEEMEVSLAKPK 85.79799999999999 0.0006951 34592000.0 61279.0 60629.0 89750.0 93749.0 82737.0 80017.0 71237.0 76597.0 72337.0 77912.0 True False 80764.44731761844 80226.13858528511 88559.85635839186 72136.61645761142 71250.39569457663 75013.52434067437 77576.9549956449 64760.6936739555 76160.58614108764 75184.32459456698 1.0742192305795442 1.0670593773091162 1.1779031977204386 0.9594635164525267 0.947676208821398 0.9977282464820473 1.0318235272309786 0.8613589870385733 1.0129849081146258 1.0 16.19814428098647 -5.780129114507396 24.994541773668455 0.9696538515367961 1.1024604807913867 0.5751420917812164 0.05244880625612591 161.40854182397956 215857.6685729705 0.014589897171903869 0.021682417345881316 1.6590935903308817e-06 5.780129114507396 0.13280662925459064 SGS(ph)PVATFK ddPTM_PC-9_AZD4547_30min_R2 1 SGSPVATFK 9 0 Q9BQ67 Q9BQ67 GRWD1 Glutamate-rich WD repeat-containing protein 1 1 S(0.018)GS(0.974)PVAT(0.008)FK 70.942 0.036316 15343000.0 138400.0 120290.0 146060.0 211600.0 171050.0 176440.0 166280.0 200200.0 139330.0 175580.0 True False 182408.32110116715 159171.39010084193 144123.1489660913 162818.8891874111 147302.66003791895 165407.1789078392 181078.59787295703 169263.69013833316 146694.6993521673 169432.9976423929 1.0765808528404845 0.9394356017756988 0.8506203099249838 0.960963280193262 0.8693859052698667 0.9762394646227611 1.0687327757438576 0.9990007406679006 0.8657976981661076 1.0 17.37035534614985 -6.979190538555423 24.95979039776848 0.9888976356745881 0.9343801109319553 0.07415961084980827 0.07344780754945245 559.5480333049578 671144.5257491659 0.026454572803821703 0.023328884601203054 1.0490820625998078e-07 6.979190538555423 -0.05451752474263283 SGS(ph)PVATFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGSPVATFK 9 0 Q9BQ67 Q9BQ67 GRWD1 Glutamate-rich WD repeat-containing protein 1 1 S(0.02)GS(0.951)PVAT(0.029)FK;S(0.071)GS(0.927)PVAT(0.002)FK 73.9 0.028347000000000004 20434100.0 218870.0 205236.0 213610.0 250670.0 269900.0 231360.0 217410.0 233910.0 227830.0 162130.0 True False 255920.36812045303 225610.47372252832 218703.27252043656 236625.7725831046 217015.03249336118 219227.07431399706 196815.35088790776 227770.11034813133 231161.58273798553 191522.8855796259 1.3362390992905848 1.177981801181303 1.1419171753733335 1.2354960707018332 1.133102353990677 1.1446521059377686 1.0276335921540902 1.1892579294573942 1.206965851827038 1.0 17.547157268359975 -1.5228787452803376 0.7253074858891441 1.1306583625410482 29.665305359082964 0.4388602214799582 0.06887880260917592 333.35373574068444 1.5952460896203524 0.02622596203469848 15488.474625350877 0.029999999999999995 1.5228787452803376 28.534646996541916 SGS(ph)PVATFK ddPTM_PC-9_Lapatinib_30min_R1 1 SGSPVATFK 9 0 Q9BQ67 Q9BQ67 GRWD1 Glutamate-rich WD repeat-containing protein 1 1 S(0.041)GS(0.957)PVAT(0.002)FK 72.289 0.032687 17524000.0 185570.0 157270.0 170950.0 143750.0 175220.0 176560.0 115900.0 142140.0 178690.0 136370.0 True False 182923.7377706302 156905.85097763967 156895.15088608337 154321.8545359427 164913.9040957743 169008.9403814625 121900.73489694469 148744.34330758118 158564.05051088103 159941.3727983968 1.1436924328591467 0.9810210343474833 0.9809541342617264 0.964865136742715 1.0310897125013758 1.0566930708697568 0.7621588633642551 0.9299929136851334 0.9913885803065361 1.0 17.287183650343714 SGS(ph)QPACLDHMQDR ddPTM_PC-9_AZD4547_30min_R2 1 SGSQPACLDHMQDR 14 0 O75815;O75815-3 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 SGS(1)QPACLDHMQDR 151.49 0.00021486 3419800.0 6032.4 10634.0 10900.0 16850.0 14387.0 15998.0 12485.0 14963.0 16452.0 13903.0 True False 7950.577718285259 14071.232540796016 10755.458878066514 12965.4928299049 12389.613387696818 14997.642530988533 13596.140813350188 12650.812165533864 17321.619132576325 13416.260201743851 0.5926075969555092 1.0488192930968223 0.8016733960383771 0.9664014140259176 0.923477422276471 1.1178705768571136 1.0134076567464723 0.9429462439830666 1.291091471997901 1.0 13.711694954193833 -3.7029610144788228 0.4023276100223688 1.0770063496343105 3.909636153628235e-13 0.46131429314534345 0.128730667640096 12.765754924953773 0.829137573145967 0.09377329484756865 7.892618793053106 0.0001981704910476579 3.7029610144788228 -1.0770063496339195 SGS(ph)QPACLDHMQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGSQPACLDHMQDR 14 0 O75815;O75815-3 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 S(0.002)GS(0.998)QPACLDHMQDR;S(0.086)GS(0.914)QPACLDHMQDR 105.53 0.0034592 0.0 19233.8 24416.0 27814.0 27344.0 31899.0 24158.0 24703.0 18303.9 20572.0 15556.3 True False 22489.7024551339 26839.859120277433 28477.191245182385 25812.00433044412 25648.619938887503 22891.111952271538 22362.95300576781 17823.44201958515 20872.82658159966 18376.534046396966 1.2238272134643033 1.4605506703555913 1.5496497420723265 1.4046176643143982 1.3957267390101973 1.2456708046509855 1.216929860076223 0.9699022663677833 1.1358413141945085 1.0 14.165577068614157 -7.2188119419578864 1.2707938617501617 1.0345293844763404 1.4239628736588243 0.7459679187954283 0.09211141213745581 0.22463759233836458 0.7120696328425146 0.05787082774218263 0.034580305710218154 6.042102076272746e-08 7.2188119419578864 0.389433489182484 SGS(ph)SFSR ddPTM_PC-9_Lapatinib_30min_R1 1 SGSSFSR 7 0 A6PW57;Q99755-4;Q99755-3;Q99755 A6PW57 PIP5K1A Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha 1 S(0.003)GS(0.436)S(0.436)FS(0.125)R 77.318 0.02997 29479000.0 74774.0 92177.0 104880.0 89583.0 109190.0 74014.0 78694.0 83969.0 104490.0 81911.0 True False 73707.70904812786 91963.56981983797 96257.17124850785 96171.23266012741 102767.65887579955 70848.59375506097 82768.39026730081 87870.50628390556 92721.23587152018 96069.20721045308 0.7672355293477209 0.9572637527691767 1.001956548237595 1.0010619994963716 1.069725272643008 0.7374745333315511 0.861549633546835 0.9146583888364238 0.9651504219078367 1.0 16.55178646170706 -6.7375954886928975 24.999741319577527 0.8882939881178261 0.9640005678428898 0.09286518830623358 0.09761959532157183 530.1666591314907 555865.6474858613 0.03314100768372508 0.03312424397844689 1.829803741591352e-07 6.7375954886928975 0.07570657972506367 SGS(ph)SGGQQPSGMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSSGGQQPSGMK 13 0 J3QTB2;J3QTA6;Q9BRQ6;H0Y922 J3QTB2 CHCHD6 MICOS complex subunit MIC25 1 S(0.002)GS(0.681)S(0.305)GGQQPS(0.012)GMK 83.292 0.008415100000000002 1661400.0 11564.0 9810.0 7203.9 11140.0 12711.0 11675.0 10558.0 12153.0 11112.0 8424.6 True False 13521.556800588996 10783.87196796861 7375.66829694289 10515.86191636729 10220.370796676978 11062.742447337127 9557.869806699442 11833.996627167875 11274.491978161346 9951.913290903094 1.3586891691418639 1.0835978623151787 0.7411306832511178 1.0566673572186058 1.0269754667194777 1.1116196578450324 0.9604052534738379 1.1891177385945642 1.1328969263093562 1.0 13.280758200262328 -7.766250752721527 24.998732155036922 1.1207554714964953 1.039894131740137 0.027060448816220273 0.1497043355371969 427.96721700706905 2223558.474822998 0.08086710175337786 0.040775250095923234 1.7129679893653262e-08 7.766250752721527 -0.08086133975635845 SGS(ph)SPGLR ddPTM_PC-9_AZD4547_30min_R2 1 SGSSPGLR 8 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.036)GS(0.838)S(0.126)PGLR 109.48 0.0037773000000000004 369970000.0 27542.0 30541.0 43723.0 46738.0 45034.0 38604.0 40518.0 50415.0 33772.0 43213.0 True False 36299.78309081173 40412.780988193634 43143.204451899284 35963.27619490178 38781.806443423826 36190.08577736475 44124.02350623333 42624.52017144887 35557.11897309554 41700.12602301352 0.8704957647077267 0.9691285097289771 1.0346060927511191 0.8624260793613505 0.9300165285356901 0.8678651416399106 1.058126862299699 1.0221676583884949 0.8526861274585171 1.0 15.347764123231425 -7.253066701354902 24.930353838034303 0.9850924683274869 0.9272632569559109 0.15192626468246462 0.06978508375717166 1290.308316812675 3842007.311053179 0.027466654514139918 0.0208987422272396 5.5838442837374365e-08 7.253066701354902 -0.05782921137157593 SGS(ph)SPGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SGSSPGLR 8 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.035)GS(0.845)S(0.121)PGLR;S(0.023)GS(0.53)S(0.447)PGLR;S(0.036)GS(0.838)S(0.126)PGLR;S(0.041)GS(0.816)S(0.143)PGLR 120.87 0.0033970999999999997 797561000.0 268692.0 330344.0 345651.0 363460.0 372565.0 350518.0 302556.0 310840.0 301350.0 232132.0 True False 314176.24869109725 363138.36915256025 353892.63072871725 343096.5145532196 299563.5627302306 332136.2190283267 273895.7053642511 302680.7793622042 305756.67365181167 274215.6940440993 1.1457267235790358 1.3242800358981657 1.2905630072063063 1.251192116298212 1.0924377022784657 1.2112225020020648 0.9988330767100561 1.1038054565670743 1.1150225180132831 1.0 18.064951616931268 -6.538428780849325 1.196936968896946 1.0697011279508541 1.2650316768032213 0.5682407863068728 0.07078551926538335 0.3354679792952711 1.0097437043174875 0.03179563889993763 0.03548422056062204 2.894484439309713e-07 6.538428780849325 0.19533054885236711 SGS(ph)SPGLR ddPTM_PC-9_Lapatinib_30min_R1 1 SGSSPGLR 8 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.299)GS(0.599)S(0.101)PGLR 88.177 0.011170999999999999 12197000.0 73652.0 77195.0 77646.0 75161.0 81183.0 67771.0 60974.0 65628.0 72737.0 50830.0 True False 72601.7089738775 77016.25972034657 71262.24560222754 80688.5906697458 76407.97555191898 64872.592311917055 64130.93537192668 68677.31646679308 64544.593105433756 59615.8977732824 1.2178246354685418 1.291874526711604 1.1953564110237151 1.3534743865906753 1.2816711381668089 1.0881760526131086 1.075735462641439 1.151996682629372 1.0826741777989328 1.0 15.8634094850738 -6.763516157954912 24.986835791405856 1.0889674257004696 1.2700727165025714 0.7591916553358834 0.0528973342879669 27.421750136497064 329922.0986802216 0.01781125932969122 0.01648336401710212 1.7237879561890208e-07 6.763516157954912 0.1811052908021018 SGS(ph)SQELDVKPSASPQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGSSQELDVKPSASPQER 18 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.181)GS(0.639)S(0.181)QELDVKPSASPQER;S(0.007)GS(0.982)S(0.008)QELDVKPS(0.003)ASPQER 184.66 7.1865e-10 16821500.0 36394.0 44532.0 39046.0 47648.0 54236.0 47890.0 56518.0 58273.0 47051.0 41163.0 True False 42554.78538573466 48952.84265826486 39977.004722779595 44978.43703690027 43608.84513638368 45378.564094473244 51164.20588511451 56743.39549534714 47739.0318632532 48625.52605387127 0.8751532135321076 1.0067313740530224 0.8221403029859226 0.9249964100556884 0.8968303003667312 0.9332251551211851 1.0522087890304916 1.1669466656768348 0.981768954239468 1.0 15.569426237487992 -7.233103879708568 3.91770737426411 1.0658723236672634 0.9083457716298047 0.5380602704045685 0.06352704851973907 0.15882994600268813 5.473345542472998 0.0252474016036134 0.018222528668607303 5.846502238390153e-08 7.233103879708568 -0.1575265520374587 SGS(ph)SQELDVKPSASPQER ddPTM_PC-9_Lapatinib_30min_R1 1 SGSSQELDVKPSASPQER 18 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.292)GS(0.627)S(0.081)QELDVKPSASPQER 175.16 1.1396e-07 16317000.0 34557.0 35058.0 37646.0 37055.0 35875.0 33654.0 27974.0 32138.0 37125.0 32543.0 True False 34064.21084302233 34976.82535495709 34550.891197762394 39780.14831185635 33764.903032963724 32214.696871305707 29422.35684216678 33631.24880553718 32943.59155641871 38168.01418917819 0.8924805643328593 0.9163910173999594 0.9052315644851819 1.0422378307314517 0.8846387151715406 0.8440233938196231 0.7708642293082392 0.8811369813175315 0.8631203969149444 1.0 15.22007650731456 -6.50984645203988 24.512612202991065 0.8587832268513735 0.9385951291782614 0.18077387087613894 0.06548495545429016 688.8033621756449 1295582.3257158508 0.020497756547152742 0.02218794900367362 3.091388222020396e-07 6.50984645203988 0.07981190232688784 SGS(ph)SSPDSEITELK ddPTM_PC-9_Lapatinib_30min_R1 1 SGSSSPDSEITELK 14 0 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 1 S(0.029)GS(0.537)S(0.231)S(0.197)PDS(0.006)EITELK 84.17299999999999 0.0073905 1994000.0 5861.3 12079.0 10216.0 10373.0 13310.0 15362.0 12141.0 13482.0 12176.0 10567.0 True False 5777.716787169223 12051.031817631541 9376.079914900407 11135.865023313614 12527.131968466825 14705.003070571054 12769.601573630762 14108.422938460777 10804.6106610358 12393.491870357566 0.4661895814034636 0.9723677510496367 0.7565325424810964 0.8985252211241683 1.0107830867609553 1.1865100832269961 1.0303473554674907 1.1383735178142118 0.8717971314346031 1.0 13.597295104097718 -4.368390473810892 0.6606774785123656 1.0477754842730551 7.277688657758885e-14 0.6071283995460999 0.12250557904994346 3.7044688313116767 0.8309779985096565 0.05362413679297066 3.302555134689496 4.281633859387859e-05 4.368390473810892 -1.0477754842729823 SGS(ph)SSPDSEITELKFPSINHD ddPTM_PC-9_AZD4547_30min_R2 1 SGSSSPDSEITELKFPSINHD 21 1 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 1 S(0.105)GS(0.31)S(0.31)S(0.265)PDS(0.009)EITELKFPSINHD 52.91 0.012707 4128800.0 6670.1 2771.7 17476.0 18891.0 15636.0 7504.9 6426.5 11876.0 5684.0 9481.6 True False 8791.053053301257 3667.5978214523507 17244.256821384453 14535.971813040554 13465.211297006153 7035.617416603064 6998.44605021987 10040.837083330898 5984.444635884014 9149.65206997443 0.9608073603312245 0.4008456052102755 1.8846898974413837 1.588691209444118 1.471663752241869 0.7689491756403722 0.7648865767460191 1.097400972904859 0.6540625359430458 1.0 13.159501168335686 -6.771656081716016 24.99185761050427 0.85738653168312 1.266351130328542 0.21330502848873922 0.38813913378095266 372.2454593085125 910572.5650989573 0.14796357108693367 0.13193611825068657 1.6917801238839587e-07 6.771656081716016 0.408964598645422 SGS(ph)TESLNPR ddPTM_PC-9_AZD4547_30min_R2 2 SGSTESLNPR 10 0 Q96JB2 Q96JB2 COG3 Conserved oligomeric Golgi complex subunit 3 1 S(0.018)GS(0.925)T(0.057)ESLNPR;S(0.09)GS(0.871)T(0.036)ES(0.003)LNPR 91.12299999999999 0.0082726 9817700.0 22663.0 31586.0 33097.0 34070.0 30635.0 30052.0 31491.0 43205.0 32221.0 30039.0 True False 29869.36258031611 41795.556802104824 32658.112154804356 26215.687876252796 26381.859048591945 28172.843689290366 34293.6379938495 36528.6600021313 33924.136279524755 28987.34375316002 1.0304277216521411 1.4418553544613253 1.12663348642437 0.9043839304315326 0.9101164726663152 0.9719015281011782 1.183055552998402 1.2601589270541276 1.1703085514976361 1.0 14.823135518063722 -5.512289699048901 24.55360025369902 1.059847103139204 1.2481672786417144 0.1929920476019008 0.14502986781249874 621.4787724374756 1441065.3361045262 0.0416519326653073 0.07866005657135913 3.0740455679403835e-06 5.512289699048901 0.18832017550251035 SGS(ph)TESLNPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSTESLNPR 10 0 Q96JB2 Q96JB2 COG3 Conserved oligomeric Golgi complex subunit 3 1 S(0.044)GS(0.936)T(0.02)ESLNPR 103.21 0.0029170000000000003 5224400.0 13181.0 20592.0 22286.0 18912.0 26960.0 18786.0 19300.0 14886.0 12996.0 13393.0 True False 15412.282963383219 22636.237672213003 22817.382760125656 17852.421953531255 21677.381533979333 17800.829089137074 17471.76428010033 14495.25827302075 13186.041913983518 15821.044881070338 0.9741634057194163 1.4307675531150885 1.4422171817125897 1.1283971499816319 1.370161180688895 1.125136122357855 1.1043369392754239 0.9162010715464265 0.8334494980012626 1.0 13.949557263491554 -7.395086499379956 1.4755192254336646 0.8995745089540989 1.2785101950938438 0.5213173388436609 0.14197287223692667 0.3147958068866633 1.3236572477172324 0.08949887723092936 0.04731755695966069 4.0263683228193876e-08 7.395086499379956 0.37893568613974493 SGS(ph)TGSSLSVSVR ddPTM_PC-9_AZD4547_30min_R2 2 SGSTGSSLSVSVR 13 0 Q5TH69 Q5TH69 ARFGEF3 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 1 S(0.018)GS(0.489)T(0.489)GS(0.001)S(0.001)LS(0.002)VSVR;S(0.027)GS(0.486)T(0.486)GSSLSVSVR 139.48 4.9217e-05 23123000.0 30046.0 32534.0 40293.0 42854.0 40040.0 40963.0 37111.0 31096.0 35879.0 31151.0 True False 39600.00300437615 43049.9792629544 39758.68849302147 32974.67238769996 34481.13714070905 38401.577134447 40413.80710646689 26290.827714993055 37775.49069156975 30060.412971626443 1.3173472713682934 1.4321153639369029 1.322626157217104 1.096946752488871 1.1470613252471036 1.2774800256634415 1.3444195575294609 0.8745996849680195 1.2566524194868995 1.0 14.875577208764637 -1.522878745371125 0.13326525648519785 0.9530756954229999 2.430216968807179 0.35270564437022434 0.13258739879428105 89.89600160191628 0.8096210797673058 0.6730499549701485 25.04745736018625 0.029999999993728627 1.522878745371125 1.4771412733841793 SGS(ph)TGSSLSVSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSTGSSLSVSVR 13 0 Q5TH69 Q5TH69 ARFGEF3 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 1 S(0.02)GS(0.669)T(0.308)GS(0.001)S(0.001)LSVSVR 113.52 0.00033546 5523500.0 9919.0 13873.0 9721.4 10735.0 12972.0 14234.0 16012.0 13013.0 14544.0 15260.0 True False 11598.090790819982 15250.219756537053 9953.195044614808 10133.552753339574 10430.229720281153 13487.543982475085 14495.227443158894 12671.4225384132 14756.678485455252 18026.51720190646 0.6433905485410895 0.845988139901157 0.5521418770544413 0.562147010420175 0.5786048188597444 0.7482057588500046 0.8041058225948327 0.7029323743730758 0.8186095139828011 1.0 14.13783306856069 -8.579410504556046 0.5861130292479145 1.0025314661006122 0.6482605156786496 0.5774368256129697 0.08979098787856066 0.7661038834214136 0.610120106871452 0.10476919099954562 0.044941849465118616 2.6338406456028798e-09 8.579410504556046 -0.35427095042196255 SGS(ph)TGSSLSVSVR ddPTM_PC-9_Lapatinib_30min_R1 1 SGSTGSSLSVSVR 13 0 Q5TH69 Q5TH69 ARFGEF3 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 1 S(0.003)GS(0.734)T(0.258)GS(0.003)S(0.003)LSVSVR 116.63 0.000271 8124600.0 12841.0 17414.0 21255.0 17708.0 22084.0 29343.0 21174.0 22865.0 30494.0 21388.0 True False 12657.884985248997 17373.678952912975 19507.495946672694 19010.305392156304 20785.062538814513 28088.06829187386 22270.286114822295 23927.391372786344 27059.4446039443 25084.88730228139 0.504602027217312 0.692595455724168 0.7776593018577584 0.7578389794251688 0.8285890340405946 1.119720728795913 0.8877969371142793 0.9538568415497815 1.0787150158527254 1.0 14.61453083613661 -4.424970980274365 0.3881764637115402 1.03260116145273 1.3727204511336616e-15 0.8074445055142846 0.07812917114116741 3.390813967908075 0.3276431140741297 0.06700218182222063 1.7237208139851568 3.758625187285612e-05 4.424970980274365 -1.0326011614527286 SGS(ph)VSNYR ddPTM_PC-9_AZD4547_30min_R2 4 SGSVSNYR 8 0 Q13131;Q13131-2 Q13131 PRKAA1 5-AMP-activated protein kinase catalytic subunit alpha-1 1 S(0.067)GS(0.932)VS(0.001)NYR;S(0.04)GS(0.96)VSNYR;S(0.047)GS(0.953)VSNYR;S(0.211)GS(0.788)VSNYR 112.85 0.0037234 219799000.0 118139.0 106874.0 151366.0 207244.0 194000.0 158834.0 144728.0 196578.0 138302.0 137159.0 True False 155704.74455614714 141418.9304650208 149358.78793921237 159467.09768788196 167066.44868375538 148902.08487104863 157608.5116247131 166201.38701305294 145612.36137087105 132357.10515795034 1.1763988368462317 1.0684649705526301 1.1284531175033847 1.2048246106439053 1.2622401229188576 1.125002580657488 1.1907824021734883 1.255704307031451 1.1001476739545062 1.0 17.01407611770987 -4.43289280574964 22.532736575567714 1.1593744279053497 2.993023057434815 0.0 0.07888160411114294 7687.143805128746 1935435.6324829897 0.018714148397967003 3970.483122172853 3.6906868229410156e-05 4.43289280574964 1.8336486295294654 SGS(ph)VSNYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SGSVSNYR 8 0 Q13131;Q13131-2 Q13131 PRKAA1 5-AMP-activated protein kinase catalytic subunit alpha-1 1 S(0.018)GS(0.973)VS(0.009)NYR;S(0.035)GS(0.965)VSNYR;S(0.05)GS(0.95)VSNYR;S(0.046)GS(0.954)VSNYR 134.84 0.0038329 131260600.0 241048.0 217167.0 213808.0 206498.0 309737.0 289792.0 255794.0 334468.0 256407.0 231091.0 True False 281852.66548498557 238725.9045532968 218905.99359135507 194928.58653554873 249046.25831565887 274594.7973703398 231563.34053181257 325688.56939813914 260156.46730061388 272985.9689846502 1.0324804111116566 0.8744988082765535 0.8018946702849185 0.7140608261317248 0.9123042449469722 1.0058934471675358 0.848260961517891 1.193059740797346 0.9530030728987476 1.0 18.058467275411722 -7.122658766934567 1.3290025768401497 1.0346576383493837 0.8567019489728815 0.26311750395945976 0.10989146213349585 0.5633105427728821 1.9842554985243128 0.06476643964503201 0.04238988423356432 7.539477214924808e-08 7.122658766934567 -0.1779556893765022 SGS(ph)VSNYR ddPTM_PC-9_Lapatinib_30min_R1 3 SGSVSNYR 8 0 Q13131;Q13131-2 Q13131 PRKAA1 5-AMP-activated protein kinase catalytic subunit alpha-1 1 S(0.096)GS(0.904)VSNYR;S(0.029)GS(0.969)VS(0.002)NYR;S(0.05)GS(0.95)VS(0.001)NYR 103.31 0.004011 136375000.0 131105.0 117746.0 124776.0 133003.0 133889.0 153175.0 151459.0 125003.0 189629.0 161832.0 True False 129235.41865828763 117473.36637129249 114517.39892928858 142784.4843050018 126013.91225590197 146624.06231836483 159300.80592542145 130811.0957258874 168270.98513810436 189804.4455724147 0.6808872061375474 0.6189178868651617 0.6033441344533609 0.7522715491430694 0.663914440338147 0.7725006749772066 0.8392891190983437 0.6891887876039237 0.8865492303440552 1.0 17.53415425778723 -8.487575224827907 0.20645815233902187 1.1029252922655453 0.558979763514123 0.7583480884874135 0.05903082576041709 1.769653466900971 0.29469613984441984 0.3584370655111507 0.2354158042000399 3.2540541463442033e-09 8.487575224827907 -0.5439455287514222 SGS(ph)VYEPLK ddPTM_PC-9_AZD4547_30min_R2 1 SGSVYEPLK 9 0 Q93100-4;Q93100-2;I3L3F2;H3BV13;H3BQ89;Q93100-3;Q93100 Q93100-4;Q93100-3 PHKB Phosphorylase b kinase regulatory subunit beta 1 S(0.046)GS(0.947)VY(0.008)EPLK 92.866 0.0066979 36537000.0 133780.0 132950.0 139080.0 194430.0 214430.0 139200.0 164390.0 200120.0 172410.0 145640.0 True False 176319.25720313675 175923.48752104834 137235.7083267423 149607.16741355555 184660.09583122496 130495.8019948498 179020.391534372 169196.05230011584 181523.24061800886 140541.18792936593 1.2545735510059328 1.251757510470632 0.9764803496304234 1.0645076337959094 1.3139215524777874 0.928523544716551 1.2737930721372954 1.2038894418990642 1.291601723967496 1.0 17.100633472593643 SGS(ph)VYEPLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SGSVYEPLK 9 0 Q93100-4;Q93100-2;I3L3F2;H3BV13;H3BQ89;Q93100-3;Q93100 Q93100-4;Q93100-3 PHKB Phosphorylase b kinase regulatory subunit beta 1 S(0.055)GS(0.94)VY(0.005)EPLK;S(0.477)GS(0.52)VY(0.003)EPLK;S(0.003)GS(0.997)VYEPLK 96.229 0.005171800000000001 53036000.0 220875.0 212446.0 152214.0 162519.0 216984.0 158737.0 145847.0 185115.0 136162.0 115338.0 True False 258264.7750198973 233536.23487329896 155843.35903480987 153413.58732370735 174467.54283267682 150412.55227948222 132031.31631916008 180255.92739555487 138153.11165680405 136247.86638489424 1.8955509680445979 1.7140542532502443 1.14382238173594 1.1259889156012228 1.2805157795265114 1.1039626254004842 0.9690523589277897 1.3230000012355407 1.013983670515086 1.0 17.05587411217934 -5.192130194817069 3.2020662156213904 1.1274884297070165 1.8673771013069576 0.8646764389093452 0.10930983639565259 0.08181164999792966 1.6221476631905571 0.028154546187086727 0.09089403278191235 6.424950782844133e-06 5.192130194817069 0.7398886715999411 SGS(ph)VYEPLK ddPTM_PC-9_Lapatinib_30min_R1 3 SGSVYEPLK 9 0 Q93100-4;Q93100-2;I3L3F2;H3BV13;H3BQ89;Q93100-3;Q93100 Q93100-4;Q93100-3 PHKB Phosphorylase b kinase regulatory subunit beta 1 S(0.013)GS(0.987)VYEPLK;S(0.009)GS(0.988)VY(0.003)EPLK;S(0.492)GS(0.507)VYEPLK 103.34 0.0028868 78168400.0 439154.0 353083.0 351926.0 354834.0 287268.0 293848.0 311315.0 241801.0 316314.0 239982.0 True False 432891.5834290199 352265.45800685574 322992.0027536456 380929.67605152493 270371.461030618 281280.80603314453 327433.36742400617 253035.95719794897 280687.38638591295 281462.56894408533 1.5380076471732094 1.251553481261787 1.147548691697653 1.3533937300458574 0.9605947321696241 0.9993542199532155 1.1633282842986248 0.8990039355755916 0.9972458769168472 1.0 18.10258354882275 -1.522878745280351 0.34725387641293176 0.9718197690386536 7.120899024168683 0.7022405969168055 0.10442314935723919 34.49562776745219 0.4865588664978258 0.08977283322667695 138.5110907479739 0.029999999999999076 1.522878745280351 6.1490792551300295 SGS(ph)YSYLEER ddPTM_PC-9_AZD4547_30min_R2 2 SGSYSYLEER 10 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;A0A0U1RQZ1;H0YIM2;H0YIS3 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 S(0.012)GS(0.948)YS(0.04)YLEER;S(0.001)GS(0.999)YSYLEER 206.36 5.908e-05 43907000.0 41794.0 52290.0 57244.0 86530.0 81062.0 65156.0 61543.0 90051.0 68664.0 71985.0 True False 55083.622630796024 69191.71991331794 56484.907157434835 66581.84537517329 69807.94053197186 61081.78501994552 67020.2077754113 76135.68711611922 72293.43885966577 69464.8270605287 0.7929714211020564 0.9960684110395498 0.8131439974393989 0.9584972451908172 1.0049393842317378 0.8793196154756342 0.9648078115419871 1.0960321984214807 1.0407200581766702 1.0 16.083995045586477 -6.880459038132654 0.5997555408898216 1.0487377076482045 0.8755624891546211 0.4092136799261944 0.07113621300262053 0.8626944371958772 0.6680921847275233 0.05979549279971251 0.06054124921279338 1.3168641110974703e-07 6.880459038132654 -0.17317521849358342 SGS(ph)YSYLEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGSYSYLEER 10 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;A0A0U1RQZ1;H0YIM2;H0YIS3 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 S(0.013)GS(0.985)YS(0.002)YLEER;S(0.052)GS(0.947)YS(0.001)YLEER 152.67 0.00017102 25250700.0 14696.8 16633.1 20086.3 20743.4 33610.0 28128.0 23087.6 23717.4 28994.0 20744.6 True False 17184.677964968552 18284.324243671625 20565.233569716955 19581.214549010176 27024.361771403765 26652.91816348598 20900.575388251007 23094.84338066253 29417.982398741016 24505.431765836747 0.7012599544940837 0.7461335273905263 0.8392112314620442 0.7990560923847313 1.1027906804351304 1.0876330773589171 0.8528956187333412 0.9424377256988088 1.2004678260659296 1.0 14.580813945637821 -6.178096312713296 5.77129694653581 1.0216963820338687 0.7709487701018054 0.6455449533187401 0.09419062959905325 0.1634808346805134 8.87564523969967 0.029519059303652888 0.03829973122368353 6.635958896046561e-07 6.178096312713296 -0.2507476119320633 SGS(ph)YSYLEER ddPTM_PC-9_Lapatinib_30min_R1 2 SGSYSYLEER 10 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;A0A0U1RQZ1;H0YIM2;H0YIS3 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 S(0.362)GS(0.638)YSYLEER;S(0.053)GS(0.82)YS(0.127)YLEER 171.67 0.00040998 25867600.0 43662.0 40830.0 51816.0 39872.0 42403.0 34673.0 55056.0 50505.0 48694.0 41884.0 True False 43039.37187336982 40735.460643587736 47555.888495544175 42804.31988909288 39908.93890750553 33190.11661671071 57906.5302889231 52851.64667756724 43209.56894944784 49123.59359307807 0.8761446125031543 0.8292443134560845 0.9680865143841024 0.8713597022984161 0.8124189618148995 0.675645126690965 1.1787926341179287 1.0758912940158858 0.8796092832169436 1.0 15.584128483198825 -7.266816680392018 24.999314031464362 1.0398975691482892 0.8445366907076188 0.4892934131154645 0.09728537036967552 414.47203621358506 1926889.022663998 0.041394187830832846 0.028817760468901093 5.4098262839174443e-08 7.266816680392018 -0.1953608784406704 SGSALLQS(ph)QSSTEDPKDEPAELKPDSEDLSSQSSASK ddPTM_PC-9_Lapatinib_30min_R1 1 SGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASK 37 2 Q5VTR2 Q5VTR2 RNF20 E3 ubiquitin-protein ligase BRE1A 1 S(0.002)GS(0.004)ALLQS(0.278)QS(0.234)S(0.234)T(0.234)EDPKDEPAELKPDS(0.002)EDLS(0.002)S(0.002)QS(0.007)S(0.002)AS(0.001)K 40.318000000000005 0.015291999999999998 7508500.0 23347.0 20699.0 16708.0 15198.0 21912.0 24161.0 26515.0 23131.0 20608.0 32269.0 True False 23014.067498684562 20651.072737242772 15334.332734745114 16315.71161904177 20623.179240649508 23127.690352041875 27887.816961108616 24205.75070386709 18286.910028139442 37846.65365426028 0.6080872488470045 0.5456512199439367 0.4051701076356318 0.4311005080684369 0.5449142063931991 0.6110894390642768 0.7368634811381632 0.6395743973824837 0.4831843310427246 1.0 15.207878124414906 -6.828302376343135 2.4962554635394283 0.6842573293787235 0.49483069809310704 0.3475837957174085 0.1318847956294222 0.3647824465502017 4.643332157378891 0.05046225392959093 0.04483164043148774 1.4849014237449573e-07 6.828302376343135 -0.1894266312856165 SGSALLQSQS(ph)STEDPKDEPAELKPDSEDLSSQSSASK ddPTM_PC-9_AZD4547_30min_R2 1 SGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASK 37 2 Q5VTR2 Q5VTR2 RNF20 E3 ubiquitin-protein ligase BRE1A 1 S(0.004)GS(0.007)ALLQS(0.096)QS(0.33)S(0.33)T(0.131)EDPKDEPAELKPDS(0.01)EDLS(0.007)S(0.007)QS(0.035)S(0.035)AS(0.008)K 40.12 0.015927 7398800.0 13108.0 18581.0 19331.0 18784.0 18718.0 22802.0 20663.0 22284.0 24553.0 20684.0 True False 17276.071336662557 24586.9448787409 19074.658309348968 14453.639009907032 16119.328796198595 21376.18733539194 22501.966970464953 18840.519835377712 25850.82145405705 19959.85945571962 0.8655407306343529 1.2318195392751305 0.9556509328968751 0.7241353097686895 0.8075872894776072 1.070958810246856 1.1273609927156514 0.9439204658316793 1.295140454841697 1.0 14.284813941745155 -6.892580107217533 8.75545655423258 1.088587482058226 0.9261122455586376 0.2431946317818986 0.15026916946237284 0.4499051370304014 33.619705457372305 0.055968310507281495 0.0493705785175126 1.2806188578822563e-07 6.892580107217533 -0.1624752364995884 SGSALLQSQS(ph)STEDPKDEPAELKPDSEDLSSQSSASK ddPTM_PC-9_Lapatinib_30min_R1 1 SGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASK 37 2 Q5VTR2 Q5VTR2 RNF20 E3 ubiquitin-protein ligase BRE1A 1 S(0.001)GS(0.002)ALLQS(0.146)QS(0.282)S(0.282)T(0.282)EDPKDEPAELKPDS(0.002)EDLS(0.001)SQSSASK 54.745 0.00010582 14761000.0 118640.0 92660.0 80753.0 100650.0 128710.0 115470.0 143440.0 127560.0 122210.0 172480.0 True False 116948.17184408856 92445.45146301364 74113.80005559449 108052.13675855732 121139.53085359602 110531.61727371694 150866.6213426897 133486.90328067483 108445.42287164781 202292.93818484637 0.5781129726694981 0.456988030786033 0.3663686964093258 0.5341369685373003 0.5988322278600949 0.5463938497582057 0.7457829358572786 0.6598693186150689 0.5360811101203897 1.0 17.62608643237786 -14.522878741969155 0.12505105544181427 2.4893304971532735 0.35664547053929024 0.7236738354784813 0.08663145864658221 79.82431650518706 0.636087104241039 29.747628499119806 0.7725347111837235 3.000000022872839e-15 14.522878741969155 -2.1326850266139834 SGSARCRSESDMENERNS(ph)NT(ph)SK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSARCRSESDMENERNSNTSK 22 3 A0A2R8YFN7;A0A2R8Y6Z0;O15034-2;O15034 A0A2R8YFN7 RIMBP2 RIMS-binding protein 2 2 SGSARCRSES(0.001)DMENERNS(0.928)NT(0.579)S(0.49)K 47.236999999999995 0.024636 2757000.0 7421.3 6830.7 8662.9 10256.0 10473.0 8284.1 9607.4 11578.0 10244.0 7231.5 True False 8677.57951264364 7508.806753476372 8869.456390231198 9681.38957040063 8420.890831059553 7849.667212675422 8697.31752044746 11274.089767905027 10393.799120256017 8542.513705477499 1.0158110143949242 0.8789926492785948 1.0382724214471044 1.133318587969356 0.9857626363139504 0.9188943071454694 1.018121576424361 1.319762561302773 1.21671436284515 1.0 13.060444941956204 -7.6529838251649664 7.664973507805674 1.2002239028631505 0.9955195486622582 0.4131863006913755 0.09774803399074915 0.2009607245532884 12.856363902891918 0.046449749376949685 0.026634969143126287 2.2233926970003062e-08 7.6529838251649664 -0.20470435420089228 SGSAT(ph)PPAR ddPTM_PC-9_AZD4547_30min_R2 1 SGSATPPAR 9 0 H3BN50;Q15599-3 H3BN50 SLC9A3R2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 1 S(0.003)GS(0.032)AT(0.965)PPAR 97.59700000000001 0.011571 57797000.0 236580.0 176410.0 297630.0 374250.0 285420.0 319360.0 290430.0 345090.0 304420.0 336290.0 True False 311807.5188303046 233431.08261442743 293683.23173201265 287972.4446048608 245794.35970782148 299390.3687146197 316277.70736253826 291764.2698793082 320511.0197142522 324516.5894587093 0.9608369154575325 0.7193194129267424 0.9049868058267024 0.8873889778183488 0.7574169324218655 0.9225733858906878 0.9746118307544357 0.8990735122847443 0.9876568105466093 1.0 18.307932705875565 -6.984479504291689 24.110810457606547 0.9557346668920541 0.8440765901725719 0.3940801820583335 0.06988455991063396 163.09394582689254 253361.88833551735 0.023400423072527272 0.02062914599931613 1.0363835134406172e-07 6.984479504291689 -0.11165807671948225 SGSAT(ph)PPAR ddPTM_PC-9_Lapatinib_30min_R1 1 SGSATPPAR 9 0 H3BN50;Q15599-3 H3BN50 SLC9A3R2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 1 S(0.034)GS(0.023)AT(0.943)PPAR 84.81700000000001 0.031577 51712000.0 226560.0 255470.0 290070.0 287150.0 288870.0 258260.0 214380.0 243590.0 311180.0 236650.0 True False 223329.21285398453 254878.47491102942 266221.56430258055 308267.96890431986 271879.2345402711 247214.82183346432 225479.54743060394 254908.08066901506 276131.6315293297 277554.63718369586 0.804631531723165 0.9183001858561689 0.9591681371418966 1.1106568855496974 0.9795521245798227 0.8906888544248982 0.8123789597554923 0.9184068522707027 0.9948730611428251 1.0 18.08241227125108 -5.7147769261106784 0.006517806119894284 1.860272133162007 9.748440096159889e-08 0.05468061797790802 0.08455678962002788 61473.706782737936 87.87109638940669 12123.40716378183 12961.605029650258 1.9285152341482336e-06 5.7147769261106784 -1.860272035677606 SGSDAGEARPPTPAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 SGSDAGEARPPTPASPR 17 1 Q96FS4;F6RY50;E9PIB3 Q96FS4 SIPA1 Signal-induced proliferation-associated protein 1 1 SGSDAGEARPPT(0.049)PAS(0.951)PR 134.4 0.00014533 3330000.0 18241.0 16938.0 37653.0 51907.0 42041.0 35016.0 24489.0 45595.0 28831.0 36675.0 True False 24041.25856362996 22412.877259357032 37153.69661796685 39940.64310515568 36204.332830483254 32826.44398456646 26668.473558520855 38549.34041886764 30354.947800346952 35391.0194130012 0.6793039297081731 0.6332927853195284 1.0498057765557924 1.1285530557642862 1.0229807852661987 0.9275359831117884 0.7535378748859649 1.0892407468971126 0.857701990612788 1.0 15.11109569770988 -5.256236659038286 24.95765716169305 0.9789256122495474 0.6562983190009548 0.599329608051552 0.1054329208329851 288.87538130482574 1385735.1661065281 0.0284600871182181 0.07065873804392814 5.5432356444585335e-06 5.256236659038286 -0.32262729324859263 SGSDAGEARPPTPAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 SGSDAGEARPPTPASPR 17 1 Q96FS4;F6RY50;E9PIB3 Q96FS4 SIPA1 Signal-induced proliferation-associated protein 1 1 SGSDAGEARPPT(0.285)PAS(0.715)PR;SGSDAGEARPPT(0.052)PAS(0.948)PR 107.65 0.0027799 12600800.0 49103.0 49246.0 57022.0 44069.0 48354.0 44406.0 38751.0 38633.0 44049.0 26289.0 True False 48402.782215612635 49131.97391266519 52333.87127128533 47309.98126987441 45509.91278762167 42506.85889544186 40757.337169900806 40428.030216700405 39087.737763466306 30833.0186221094 1.5698359868308354 1.5934856886647542 1.697332068348259 1.5343934322392259 1.47601223692668 1.3786149003575507 1.3218730760495498 1.3111927415277698 1.2677233534130097 1.0 14.912188519009485 -7.665830835714633 0.3227082008425171 0.9744870869154663 1.7004659733171166 0.9324745129267893 0.049863226638892644 0.36561479937169816 0.12024089841221704 0.08419997040528274 0.09306111542349756 2.158585047025188e-08 7.665830835714633 0.7259788864016503 SGSGS(ph)ESEPSSR ddPTM_PC-9_Lapatinib_30min_R1 1 SGSGSESEPSSR 12 0 O14641;I3L2N2;I3L0Z8 O14641 DVL2 Segment polarity protein dishevelled homolog DVL-2 1 S(0.11)GS(0.22)GS(0.67)ESEPSSR 158.34 0.00046864 5855700.0 2865.5 4270.4 5353.4 3725.0 5914.7 4276.7 4430.8 4572.0 4687.8 4286.5 True False 2824.6374445316587 4260.512151172592 4913.264116721595 3998.9489262357256 5566.80897474761 4093.7955104746266 4660.205143929099 4784.431810906587 4159.810599277564 5027.415813597774 0.5618467915249407 0.8474556927734286 0.9772941604377681 0.7954283223240995 1.1072903418274904 0.8142941945247573 0.9269583652349839 0.951668210527965 0.8274252127756018 1.0 12.295601302799495 -4.777411226187319 3.1816985819289214 0.9213493938873463 0.5070133084285063 0.5927116309227629 0.09011242615518761 0.22706424493429858 3.4637813170399894 0.021227617314635724 0.23878368536133723 1.669509035437467e-05 4.777411226187319 -0.41433608545883993 SGSIGAADS(ph)PENWEK ddPTM_PC-9_AZD4547_30min_R2 2 SGSIGAADSPENWEK 15 0 D6R9T3;E7EMP6;Q96FZ2;D6RAI0;D6RGK7;D6RAZ3 D6R9T3 HMCES Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein 1 SGSIGAADS(0.999)PENWEK;S(0.001)GSIGAADS(0.999)PENWEK 93.51 0.0032542 13032500.0 35983.0 36383.0 40515.0 61397.0 58382.0 51622.0 42475.0 53235.0 42709.0 42811.0 True False 47424.8455071047 48143.093241657036 39977.744627969296 47242.87022419413 50276.66704667517 48394.06817944056 46255.192715021985 45008.75396860222 44966.51054784839 41312.19992065427 1.1479622387137602 1.1653480892840962 0.9676982756849556 1.143557358720439 1.216993216125948 1.1714231697268116 1.119649711316788 1.0894785088919905 1.0884559678306343 1.0 15.334280266906692 -8.601698253930447 1.1393823937018497 1.00172661992528 1.1322353695584173 0.29532851827762086 0.0617823975483354 0.8350726972825638 2.327420583925096 0.06326553688060854 0.019969049581306367 2.5020831953064232e-09 8.601698253930447 0.1305087496331374 SGSIGAADS(ph)PENWEK ddPTM_PC-9_Lapatinib_30min_R1 2 SGSIGAADSPENWEK 15 0 D6R9T3;E7EMP6;Q96FZ2;D6RAI0;D6RGK7;D6RAZ3 D6R9T3 HMCES Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein 1 SGSIGAADS(1)PENWEK;S(0.038)GS(0.005)IGAADS(0.956)PENWEK 174.35 6.9816e-05 13896300.0 45217.0 36767.0 54060.0 44339.0 43812.0 55723.0 54607.0 45908.0 53502.0 38293.0 True False 44572.19728821776 36681.86827045776 49615.39547763471 47599.837970568056 41235.06429770613 53339.85718665741 57434.28326589691 48041.05327539366 47476.04135896334 44911.894027784794 0.992436374663761 0.8167517550643596 1.1047273011229517 1.0598492671255495 0.9181323831988918 1.1876554828362094 1.2788212234016478 1.0696732862273188 1.0570928344636776 1.0 15.454809944394032 -6.763308192821918 24.999495660660703 1.1330139425885224 0.9809455281892959 0.31572550024760637 0.10212693833636757 60.690645344493866 811861.2408866757 0.03651747107864726 0.03383501268409489 1.724613602501547e-07 6.763308192821918 -0.15206841439922647 SGSIVELIAGGGSSCS(ph)PVLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSIVELIAGGGSSCSPVLSR 21 0 P42858 P42858 HTT Huntingtin 1 SGSIVELIAGGGS(0.021)S(0.112)CS(0.859)PVLS(0.008)R 112.57 1.4870999999999999e-05 43323000.0 89076.0 104480.0 113490.0 146540.0 154580.0 131180.0 158070.0 104790.0 125860.0 117740.0 True False 104154.80746880543 114852.08391573474 116196.03201322198 138329.83888909023 124291.15866181497 124300.68987080797 143096.4652723034 102039.37353418273 127700.4643962733 139085.32997067284 0.748855450756505 0.8257670592574511 0.8354298187862282 0.9945681468941266 0.8936324103197848 0.8937009381005004 1.0288393844446164 0.7336458385345059 0.9181447419594854 1.0 17.08561073403891 -5.267345102863657 1.960469529255048 0.9132013544300284 0.7645806386499248 0.31928449071659915 0.08021591628316987 0.489585347203503 3.37150790645997 0.02246580709352731 0.09019643039294803 5.4032479471616585e-06 5.267345102863657 -0.1486207157801036 SGSLDDS(ph)FSDFQELPASSK ddPTM_PC-9_AZD4547_30min_R2 1 SGSLDDSFSDFQELPASSK 19 0 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 SGSLDDS(0.985)FS(0.015)DFQELPASSK 124.99 4.3791e-05 0.0 4556.4 3657.1 5494.5 8285.3 5906.8 5590.3 5040.9 6797.2 5569.4 5722.2 True False 6005.240420992467 4839.186056511667 5421.639339957476 6375.252091608964 5086.742778789714 5240.737657268729 5489.530334482741 5746.848924117275 5863.787113844553 5521.867519702129 1.0875379388523274 0.8763676490327517 0.9818488619317582 1.1545463683911181 0.9211997137997459 0.9490879016147483 0.9941437955358384 1.0407437164351385 1.0619210064208255 1.0 12.430940559954692 -7.749329968453482 8.170271324488022 1.0385766065568636 0.9913742780850918 0.050641234440300886 0.07612273951839235 0.4253806014840986 183.87114834523328 0.03809487968116943 0.020780363353804548 1.7810250652434356e-08 7.749329968453482 -0.04720232847177175 SGSLDSELSVS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 SGSLDSELSVSPK 13 0 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7 Q12802-2 AKAP13 A-kinase anchor protein 13 1 SGSLDSELS(0.018)VS(0.981)PK;SGSLDSELS(0.006)VS(0.994)PK;SGSLDSELS(0.03)VS(0.969)PK 160.65 0.00014223 56628000.0 172079.0 180436.0 167618.0 184050.0 163285.0 185512.0 197257.0 197770.0 171605.0 173244.0 True False 226796.54253444835 238758.40838170666 165395.2758003444 141620.11604415395 140615.69625426232 173911.905313711 214812.49086255618 167209.1908024883 180675.68996144904 167178.78029136924 1.3566108218948223 1.4281621624800955 0.9893317531811366 0.8471177729454055 0.8411097150558751 1.0402749978831456 1.2849267741286785 1.0001819041332043 1.0807333900065341 1.0 17.351032214731255 -5.262861959132337 24.97649194924308 1.0094514236629961 1.392386518963184 0.6254684948339948 0.11821543439086729 81.82139104535308 1436585.1158030608 0.034515867204798524 0.07873572436774601 5.459313582597455e-06 5.262861959132337 0.382935095300188 SGSLDSELSVS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SGSLDSELSVSPK 13 0 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7 Q12802-2 AKAP13 A-kinase anchor protein 13 1 SGSLDSELS(0.038)VS(0.962)PK;SGSLDSELS(0.065)VS(0.935)PK;SGSLDSELS(0.001)VS(0.999)PK;SGSLDSELS(0.006)VS(0.994)PK 201.76 1.8739e-07 53739000.0 263797.0 282302.0 187805.0 249477.0 280824.0 209158.0 279616.0 243255.0 206736.0 231999.0 True False 308452.6218717546 310327.0768910772 192282.98345442893 235499.61250534738 225798.5531119521 198189.38627838448 253128.74823546852 236869.813999977 209759.1228939133 274058.5821969269 1.1254988601309832 1.1323384745094 0.7016127059880305 0.8593039145773853 0.823906156493588 0.7231643128620362 0.9236300728345042 0.8643035810123705 0.7653806029806769 1.0 18.06412478810195 -5.24631459148988 24.855974767891485 0.8277932904899482 1.1289187434307943 0.6608574475947817 0.08483417854814111 409.7032885099869 673300.8123142332 0.020475531263522858 0.05370916281629888 5.671336399012793e-06 5.24631459148988 0.30112545294084614 SGSLDSELSVS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 SGSLDSELSVSPK 13 0 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7 Q12802-2 AKAP13 A-kinase anchor protein 13 1 SGSLDSELS(0.064)VS(0.936)PK;SGSLDSELS(0.004)VS(0.996)PK;SGSLDSELSVS(1)PK;SGSLDSELS(0.004)VS(0.996)PK 192.39 5.4416e-06 79380000.0 271934.0 283853.0 217043.0 235017.0 240627.0 212039.0 233410.0 219734.0 206266.0 194321.0 True False 268056.1712934117 283195.75581837696 199198.56235020852 252300.934173729 226473.79295088374 202970.58625705083 245494.8277160985 229943.64381840485 183034.15100272762 227909.12593354276 1.1761537419593089 1.2425819047761848 0.8740262661017527 1.10702427180252 0.9937021697714836 0.8905768271703 1.0771610250819164 1.0089268820479587 0.8031014565695782 1.0 17.79809916856818 -5.250756530463919 24.917133383761303 0.9764624234586672 1.2093678543378772 0.536752319351115 0.08900655364930841 517.4742759575312 1206972.9203275533 0.022165727634058295 0.05734958306136418 5.613625929396038e-06 5.250756530463919 0.23290543087921 SGSLDSELSVS(ph)PKR ddPTM_PC-9_AZD4547_30min_R2 2 SGSLDSELSVSPKR 14 1 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7 Q12802-2 AKAP13 A-kinase anchor protein 13 1 SGSLDSELS(0.318)VS(0.682)PKR;SGSLDSELS(0.05)VS(0.95)PKR 56.25 0.032827999999999996 52728000.0 81313.0 67528.0 92057.0 139186.0 121423.0 82259.0 79490.0 103612.0 84760.0 93773.0 True False 107168.84258453173 89355.1054179869 90836.2640310248 107098.81810226366 104565.51236354411 77115.33172625223 86564.45600746531 87601.14616689782 89240.24055903041 90490.03581227972 1.1843165009554417 0.9874579517611506 1.0038261474386343 1.1835426645695954 1.1555472536276123 0.8521969411773345 0.9566186512185942 0.968075052469038 0.9861885870413182 1.0 16.465471320080773 -6.751930899006954 24.99989236367728 0.9508707056981373 1.0954943528075973 0.5144158312803988 0.07283528336014927 183.73200776590204 483071.46090118407 0.02545918208106708 0.025140615300502458 1.7703906243835606e-07 6.751930899006954 0.14462364710946007 SGSLDSELSVS(ph)PKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SGSLDSELSVSPKR 14 1 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7 Q12802-2 AKAP13 A-kinase anchor protein 13 1 SGSLDSELS(0.022)VS(0.977)PKR;SGSLDSELS(0.074)VS(0.925)PKR;SGSLDSELS(0.022)VS(0.978)PKR 66.738 0.016472999999999998 36162800.0 82677.0 65799.0 83798.0 125038.0 125858.0 137580.0 122635.0 121977.0 112311.0 101978.0 True False 96672.58315481614 72331.08986955837 85796.06212568474 118032.52623866565 101197.02837921285 130365.06260425206 111018.12499948726 118775.23299531451 113953.3359034626 120465.80414259588 0.8024898338816914 0.6004283986179162 0.7122026265987282 0.9798010902658323 0.8400477554561915 1.0821748423306783 0.9215737676733112 0.9859663814199071 0.9459392789058675 1.0 16.87826415039143 -5.742411248792387 7.077104273032235 0.9625647020040525 0.6928812487684912 0.7225027961168968 0.07374198687538959 0.07668067946959753 16.07887859377167 0.019248633130744066 0.032268115398168616 1.8096256825210633e-06 5.742411248792387 -0.2696834532355613 SGSMDPSGAHPSVR ddPTM_PC-9_Lapatinib_30min_R1 1 SGSMDPSGAHPSVR 14 0 Q07666;Q07666-3;Q07666-2 Q07666 KHDRBS1 KH domain-containing, RNA-binding, signal transduction-associated protein 1 0 76.311 0.018680000000000002 0.0 1221.1 1047.5 3501.9 3233.1 4289.2 8073.7 3346.1 2708.5 6781.9 745.15 False True 1203.6868900776851 1045.0745781082078 3213.9872997249167 3470.872959305429 4036.917688891651 7728.406671713939 3519.344685406956 2834.3467978653775 6018.051005426959 873.9481846500362 1.3772977748785982 1.1958083974128253 3.6775490311384145 3.971485976248472 4.619172806575706 8.84309482810895 4.0269489052331435 3.2431519941887212 6.8860501241693495 1.0 9.771403936360528 -5.462464034334956 1.6007795266789888 4.977149356680963 1.0341607530346733 0.3051370162086753 1.9806040873014525 0.49936767748610156 2.3710978767682764 0.5961692004558405 2.0109503751453417 3.4477515760226682e-06 5.462464034334956 -3.9429886036462896 SGSPAPET(ph)TNESVPFAQHSSLDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSPAPETTNESVPFAQHSSLDSR 24 0 O15047 O15047 SETD1A Histone-lysine N-methyltransferase SETD1A 1 S(0.28)GS(0.28)PAPET(0.433)T(0.005)NESVPFAQHSSLDSR 121.26 1.6719e-08 7831300.0 7570.8 7264.9 21108.0 17104.0 19053.0 26086.0 14045.0 12109.0 16049.0 9726.7 True False 8852.386909884053 7986.11125994854 21611.294772535774 16145.718331916169 15319.701423104918 24718.004238221525 12714.55592300566 11791.151580546022 16283.686263274969 11490.073713485164 0.77043778226545 0.6950443886687822 1.8808665036823897 1.4051884030097188 1.333298793821067 2.1512485345687193 1.1065686992141226 1.0262033016121996 1.4171959788355273 1.0 13.48810043303725 -5.237006340456405 24.481760786271863 1.4280078014579665 0.7327407632900576 0.38484627485176026 0.3447562091025405 614.9116432001441 616134.7556790935 0.0889678149838156 0.23511122827215453 5.79420237153911e-06 5.237006340456405 -0.6952670381679089 SGSPKLDPS(ph)EVYLK ddPTM_PC-9_Lapatinib_30min_R1 1 SGSPKLDPSEVYLK 14 1 Q5TCQ9-3;Q5TCQ9-2;Q5TCQ9;Q5TCQ9-1 Q5TCQ9-3 MAGI3 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 1 SGS(0.003)PKLDPS(0.94)EVY(0.056)LK 64.313 0.019593 10443000.0 197030.0 101810.0 117850.0 111130.0 101600.0 93272.0 67980.0 76710.0 114090.0 76352.0 True False 194220.3160691236 101574.26520018779 108160.82791415574 119302.87091881262 95624.08775328545 89282.9739876515 71499.67177130534 80274.22664362291 101239.98277903875 89549.341467355 2.168863700018678 1.1342826595460387 1.2078349895357468 1.3322584953045602 1.0678368616272291 0.9970254669064137 0.798438833828503 0.8964245334276042 1.1305497184024023 1.0 16.45039520243322 -2.482525934013659 1.1026431606473963 1.0221787394486002 199.99999997798008 0.8317653467637856 0.14847526597561067 119.0169706964071 1.0846353844885466 0.049715822837721926 58835.06718252691 0.003292107938339145 2.482525934013659 198.97782123853148 up SGSPRPT(ph)EPTDFLMLFEGSPSGK ddPTM_PC-9_AZD4547_30min_R2 1 SGSPRPTEPTDFLMLFEGSPSGK 23 1 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 S(0.024)GS(0.029)PRPT(0.924)EPT(0.023)DFLMLFEGSPSGK 90.758 1.3826e-05 1111100.0 6799.5 7108.3 6189.4 10544.0 10550.0 9723.9 9823.0 9615.2 6691.1 8944.0 True False 8961.599561614057 9405.91896461729 6107.324511917882 8113.243703176093 9085.314606255748 9115.862995816933 10697.227970327516 8129.3917753151945 7044.777885848616 8630.873282341727 1.0383189821531706 1.0897992192587584 0.7076137387410285 0.9400258163649935 1.052652994551986 1.0561924266073361 1.239414323486064 0.9418967825593576 0.8162300216203879 1.0 13.075290825104956 -3.626230532268047 14.160345611504855 0.990945227559162 1.0517359670962185 0.0 0.14060618139335987 0.0 0.0 0.033958902682678246 0.0 0.00023646641528679422 3.626230532268047 0.06079073953705649 SGSPRPT(ph)EPTDFLMLFEGSPSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SGSPRPTEPTDFLMLFEGSPSGK 23 1 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 S(0.092)GS(0.271)PRPT(0.577)EPT(0.06)DFLMLFEGSPSGK;S(0.01)GS(0.108)PRPT(0.702)EPT(0.18)DFLMLFEGSPSGK;S(0.206)GS(0.206)PRPT(0.564)EPT(0.024)DFLMLFEGSPSGK 65.915 0.0011022 42879900.0 95891.0 101277.0 90387.0 120053.0 136511.0 117161.0 120137.0 112665.0 101203.0 93319.0 True False 112123.45236641969 111331.11124362453 92542.16887460652 113326.81962707765 109762.64950241294 111016.870909847 108756.75364344133 109707.6631284347 102682.90241773413 110236.99598720254 1.0171127339086432 1.0099251185740676 0.839483769000289 1.0280289172632553 0.995697030016632 1.0070745298859105 0.9865721817752269 0.995198228561768 0.9314740618444886 1.0 16.75024895397214 -5.033066540360913 24.99898281473148 0.9737522062189251 1.0153161611464974 0.0936328194748518 0.050665399073901114 1356.4840956968176 1025531.614082183 0.012940641744684199 0.03429256626272418 9.266878301713716e-06 5.033066540360913 0.041563954927572255 SGSPRPT(ph)EPTDFLMLFEGSPSGK ddPTM_PC-9_Lapatinib_30min_R1 1 SGSPRPTEPTDFLMLFEGSPSGK 23 1 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 S(0.056)GS(0.236)PRPT(0.599)EPT(0.109)DFLMLFEGSPSGK 101.62 2.9852e-06 9863100.0 73173.0 57920.0 74352.0 57708.0 63865.0 63210.0 61501.0 69086.0 77425.0 60551.0 True False 72129.53960171524 57785.88979859418 68239.06556701998 61952.03882824462 60108.58626342101 60506.65564970684 64685.220853295876 72295.98777084249 68704.58117860518 71017.15967086412 1.0156635373198049 0.8136891149464224 0.9608813684365936 0.8723530920606699 0.8463952450647148 0.852000501429947 0.9108393119787637 1.018007311273856 0.9674363421041223 1.0 16.115880040517993 -7.660678492227549 5.192936439264015 0.9940150440912411 0.889315094274096 0.3944943162329173 0.05635397867934421 0.19809998647006213 8.371056655571785 0.026362560323300133 0.01472862489264611 2.1843463828851432e-08 7.660678492227549 -0.10469994981714503 SGSPRPTEPTDFLMLFEGSPSGK ddPTM_PC-9_AZD4547_30min_R2 1 SGSPRPTEPTDFLMLFEGSPSGK 23 1 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 0 111.45 4.1309e-06 2264300.0 11840.0 11088.0 13757.0 21051.0 13851.0 16235.0 12145.0 15825.0 12898.0 13585.0 False True 15604.873712700997 14671.979162342126 13574.57319133589 16198.017184707893 11928.027735663365 15219.82288352286 13225.881472017474 13379.60987232328 13579.76194821112 13109.393284952188 1.1903581938161305 1.1191958959064547 1.0354844725665273 1.23560387827414 0.9098840408850293 1.1609860618792451 1.0088858564643872 1.020612440369858 1.0358802770681121 1.0 13.678313297371103 -1.5228787482189678 0.22255525467944884 0.9984495989801713 1.9463807432495759 0.27972852475449883 0.08124723629109488 67.63530325329245 0.8701525855438702 0.11825482779156864 23.10990106522556 0.029999999797006613 1.5228787482189678 0.9479311442694046 SGSPRPTEPTDFLMLFEGSPSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSPRPTEPTDFLMLFEGSPSGK 23 1 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 0 63.606 0.014531 3920500.0 18979.0 17673.0 15293.0 18423.0 24268.0 16664.0 17157.0 18807.0 20052.0 13792.0 False True 22191.769847663298 19427.458643211958 15657.643119025466 17390.819038171874 19512.85960929564 15790.11050470457 15531.764754076748 18313.33617766365 20345.222565342996 16292.380422588081 1.3620949960692168 1.1924260383876957 0.9610408493357666 1.0674203883712963 1.1976678117730801 0.969171483549012 0.9533146385744344 1.1240430006332085 1.2487569058439105 1.0 13.991909785927897 -4.926038040633458 3.473240072665904 1.0669025757509092 1.3614257731885868 0.4791330187077175 0.09626371135512764 0.2262663434353976 5.027567947511328 0.025517848286486677 0.14295795760852645 1.185664889102095e-05 4.926038040633458 0.29452319743767763 SGSPRPTEPTDFLMLFEGSPSGK ddPTM_PC-9_Lapatinib_30min_R1 1 SGSPRPTEPTDFLMLFEGSPSGK 23 1 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 0 72.99 0.0036624 1527000.0 11534.0 8899.8 12974.0 9778.6 11063.0 11445.0 8925.1 9590.0 10180.0 7704.8 False True 11369.523044923446 8879.193059902083 11907.327801088284 10497.750864453341 10412.296090694845 10955.524029598075 9387.198007150302 10035.586410016225 9033.421199847602 9036.564413999333 1.258168760166189 0.9825850459436275 1.3176830547062333 1.1616971211083669 1.1522405655145052 1.2123549977274453 1.0388016481803386 1.1105532977189008 0.9996521671281553 1.0 13.141558667372708 -7.687300543487585 1.1070789233985185 1.0050188884068125 1.1770169543798394 0.3810499679471713 0.08754046232687014 0.5644973217581529 1.2589049048253895 0.07072399485509866 0.029267665638414483 2.054468356447415e-08 7.687300543487585 0.17199806597302691 SGSPS(ph)DNSGAEEMEVSLAKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSPSDNSGAEEMEVSLAKPK 21 1 P31749-2;P31749 P31749-2 AKT1 RAC-alpha serine/threonine-protein kinase 1 S(0.01)GS(0.313)PS(0.339)DNS(0.339)GAEEMEVSLAKPK 65.808 0.013447 0.0 11327.0 12272.0 12025.0 16252.0 18506.0 18813.0 16801.0 16563.0 15361.0 10445.0 True False 13244.43738155236 13490.28305717745 12311.72160506646 15341.453129694917 14879.882146432547 17826.413161606284 15209.487651293559 16128.23879994911 15585.625564843094 12338.595817425501 1.0734152878926109 1.0933402193242645 0.9978219391609304 1.2433710737188224 1.2059623612451953 1.4447683857534641 1.2326757336368508 1.3071372981657756 1.2631603948669663 1.0 13.590890598793269 -5.819927366072795 7.060393925854404 1.2627254892459925 1.0590695320243873 0.38462869001478606 0.1066183637867589 0.19026486655668212 18.58561220648612 0.028683264885902057 0.043074461225062935 1.5138144063642764e-06 5.819927366072795 -0.20365595722160523 SGSPSDNS(ph)GAEEMEVSLAKPK ddPTM_PC-9_AZD4547_30min_R2 3 SGSPSDNSGAEEMEVSLAKPK 21 1 P31749-2;P31749 P31749-2 AKT1 RAC-alpha serine/threonine-protein kinase 1 S(0.003)GS(0.065)PS(0.119)DNS(0.812)GAEEMEVSLAKPK;SGS(0.001)PS(0.022)DNS(0.977)GAEEMEVSLAKPK;SGSPS(0.001)DNS(0.999)GAEEMEVSLAKPK 100.02 0.00032265 99279000.0 162072.0 152216.0 181747.0 223787.0 206212.0 216014.0 182977.0 198249.0 164548.0 195303.0 True False 213607.5246929793 201416.84525388444 179336.91602862 172196.36462468386 177583.02327821925 202506.6104318634 199261.5985265823 167614.1723588136 173245.67134860018 188465.50141560685 1.1334038489194311 1.0687199712467117 0.9515636266668436 0.9136757832668482 0.9422574526603179 1.074502277131839 1.0572842086741792 0.8893626212745877 0.9192434161547494 1.0 17.52394093696722 -5.0713894699913356 3.253002020552845 0.9687870709291853 1.12665739004828 0.47470557159210713 0.05752499894011707 0.23844411699820126 4.727758357244041 0.016712304998439766 0.06475269953629491 8.484192817149698e-06 5.0713894699913356 0.15787031911909466 SGSPSDNS(ph)GAEEMEVSLAKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSPSDNSGAEEMEVSLAKPK 21 1 P31749-2;P31749 P31749-2 AKT1 RAC-alpha serine/threonine-protein kinase 1 S(0.002)GS(0.062)PS(0.082)DNS(0.854)GAEEMEVSLAKPK 111.66 3.6061e-05 17708000.0 39141.0 36763.0 33593.0 40792.0 47394.0 43600.0 42945.0 37847.0 39342.0 34016.0 True False 45766.798230011584 40412.587681797144 34393.98452216193 38506.55648944835 38107.485920675674 41313.539246586595 38876.93870512479 36853.5563522112 39917.30232224837 40182.83152949218 1.1389639925305177 1.005717769095897 0.8559373048889917 0.9582837999155552 0.9483524298855519 1.0281390751735486 0.9675012244119997 0.917146824886209 0.9933919737077531 1.0 15.294291608369903 -4.824067351262597 3.8122484700996524 0.9566855629997106 1.149285733386101 0.5871652645174779 0.0453336053759795 0.15825698978520691 3.9602059452838154 0.011544123947718195 0.07803387916810635 1.4994522793919437e-05 4.824067351262597 0.19260017038639043 SGSPSDNS(ph)GAEEMEVSLAKPK ddPTM_PC-9_Lapatinib_30min_R1 4 SGSPSDNSGAEEMEVSLAKPK 21 1 P31749-2;P31749 P31749-2 AKT1 RAC-alpha serine/threonine-protein kinase 1 S(0.001)GS(0.026)PS(0.026)DNS(0.947)GAEEMEVSLAKPK;S(0.009)GS(0.008)PS(0.031)DNS(0.952)GAEEMEVSLAKPK;SGS(0.002)PS(0.036)DNS(0.963)GAEEMEVSLAKPK;S(0.019)GS(0.017)PS(0.102)DNS(0.862)GAEEMEVSLAKPK 114.03 5.8287e-06 132629000.0 336408.0 282680.0 304527.0 297023.0 294473.0 295222.0 266688.0 276667.0 301805.0 196646.0 True False 331610.76023032825 282025.4718278077 279489.9655682148 318867.0622596812 277152.6770961931 282596.04325609474 280495.79972559406 289521.9588425399 267812.5427524566 230635.999085675 1.4378100623708092 1.2228163554079123 1.2118228146352463 1.3825554706281162 1.2016887137954488 1.22529025987447 1.2161839471616809 1.2553198979791111 1.1611914177065288 1.0 17.815258189720282 -14.522878744597051 0.10094855638865428 0.16312550727638772 1.4287492798403971 0.6372023104660719 0.06764025734437205 123.76428051939746 0.8451079658610006 21.600374184978225 1.1026222504456338 3.000000004719976e-15 14.522878744597051 1.2656237725640094 SGSS(ph)FSR ddPTM_PC-9_AZD4547_30min_R2 1 SGSSFSR 7 0 A6PW57;Q99755-4;Q99755-3;Q99755 A6PW57 PIP5K1A Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha 1 SGS(0.079)S(0.92)FSR 101.25 0.009629700000000001 0.0 94502.0 63426.0 86817.0 112960.0 112290.0 117450.0 96753.0 125040.0 121300.0 112830.0 True False 124551.67023628934 83927.21413696895 85665.74985477999 86918.81721460276 96700.47176648871 110105.83293315409 105363.82956460318 105717.94113335271 127711.67036114211 108879.85604277918 1.1439367644585483 0.7708240733161305 0.7867915422401155 0.7983002584100785 0.8881392323709065 1.011259905504405 0.9677072820816869 0.9709595968956448 1.1729595813477551 1.0 16.73237753891059 -6.731295523712728 3.6919746194930267 1.0213003854283573 0.8591617640993284 0.2952874747259219 0.11259464503288621 0.28717983598267754 8.266775848618165 0.039949106876127176 0.038036898958047925 1.8565407077080146e-07 6.731295523712728 -0.1621386213290289 SGSS(ph)FSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSSFSR 7 0 A6PW57;Q99755-4;Q99755-3;Q99755 A6PW57 PIP5K1A Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha 1 S(0.164)GS(0.117)S(0.715)FS(0.004)R 85.161 0.023932 0.0 81108.0 85456.0 86541.0 81225.0 128830.0 98921.0 74983.0 101000.0 74167.0 64319.0 True False 94837.9824439789 93939.50692097099 88604.46564856995 76674.22658500301 103586.68631389333 93733.40861953195 67880.06741009123 98348.85701834557 75251.55206482126 75979.52555107612 1.2482044571366198 1.2363792250561179 1.1661623971185093 1.009143266279807 1.3633500020246732 1.2336666745374851 0.8933994641024686 1.294412623730218 0.9904188203206732 1.0 16.21332308277051 -8.054775245340704 0.4184933730345076 0.988510715297043 1.2168638795593412 0.20786988843270837 0.13319659552189592 1.8611598037541783 0.9145468914419513 0.1642937735240036 0.1152001528534338 8.81504948541229e-09 8.054775245340704 0.22835316426229813 SGSS(ph)PEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSSPEVK 8 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.005)GS(0.147)S(0.848)PEVK 72.325 0.032987999999999996 9599100.0 20145.0 31815.0 33744.0 18348.0 112780.0 137840.0 34244.0 64019.0 94104.0 170590.0 True False 23555.150618113566 34973.382941989934 34548.58493483266 17320.021045018595 90681.56859800394 130611.42774654808 31000.160414909627 62338.56908373743 95480.09297272288 201516.61661030323 0.11688937128030974 0.1735508640938635 0.17144285923400246 0.08594835173573993 0.4499954898179227 0.6481422224308531 0.15383426407390682 0.30934704111417755 0.47380754291525323 1.0 17.620539279507106 -14.522878745201275 0.13255812388266286 3.4233055794393676 3.325510785634105e-13 0.7084532971126782 0.1491713160275869 86.4078015830633 0.7147172862782505 55.37279576237913 1.1677695184276877 3.000000000546143e-15 14.522878745201275 -3.423305579439035 SGSS(ph)PGLR ddPTM_PC-9_AZD4547_30min_R2 2 SGSSPGLR 8 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.114)GS(0.114)S(0.771)PGLR;SGS(0.393)S(0.606)PGLR 128.12 0.0036713 396601000.0 91406.0 103422.0 122354.0 146237.0 130331.0 121680.0 106596.0 145354.0 113310.0 123129.0 True False 120471.20663709026 136851.13897256006 120731.50601531654 112524.31898912774 112236.79032681718 114071.33036446344 116082.8374961857 122892.87920263405 119299.33527305034 118818.29118755097 1.0139112878414505 1.1517682808326606 1.016102022749558 0.947028591847964 0.9446086894959203 0.9600485684851787 0.976977840162274 1.0342925990128193 1.0040485692959518 1.0 16.858397419786797 -5.504429886190847 14.560383457691003 0.9800012445223426 1.0831208728922395 0.5013948122211831 0.04021851389117859 2.6311902050350167 2074.052195561483 0.01072275435873104 0.021258103922052983 3.130185777392822e-06 5.504429886190847 0.10311962836989685 SGSS(ph)PGLR ddPTM_PC-9_Lapatinib_30min_R1 2 SGSSPGLR 8 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SGS(0.367)S(0.633)PGLR;S(0.005)GS(0.432)S(0.563)PGLR 137.13 0.0032836999999999996 725690000.0 254638.0 292910.0 309930.0 273298.0 306398.0 286781.0 237742.0 259913.0 309960.0 220748.0 True False 251006.81542511014 292231.7848913369 284448.75176439784 293397.24661540135 288376.27204164513 274516.04514916235 250051.11747945982 271989.5068390565 275049.0407764995 258903.997671779 0.9694976426873084 1.1287264295617738 1.09866496586508 1.1332279503360567 1.1138347597368081 1.0603005269048615 0.9658063209841113 1.0505419355627965 1.0623591881543215 1.0 17.982057716139586 -7.004095740757079 14.669867921938057 1.022339893932891 1.0933331215858073 0.2978794685366213 0.0497194836805071 1.0652692335037275 3806.837081608576 0.017927916013010994 0.015200939802966523 9.906135388366698e-08 7.004095740757079 0.07099322765291638 SGSS(ph)PLGVVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSSPLGVVTK 11 0 Q92618;A0A087WUJ4 Q92618 ZNF516 Zinc finger protein 516 1 S(0.058)GS(0.201)S(0.74)PLGVVTK 101.72 0.003617 3572700.0 49172.0 39299.0 40780.0 50583.0 54936.0 52020.0 50623.0 50542.0 47496.0 45616.0 True False 57495.84840873071 43200.34500195705 41752.34985901125 47748.99850229866 44171.6851613757 49291.97962402377 45827.622961218614 49215.326053675584 48190.5391463959 53885.81970394266 1.0669940389627943 0.8017015467020207 0.7748300032996688 0.8861143574439309 0.8197274422855962 0.9147486276508703 0.8504579351859716 0.9133261092449272 0.8943083618503431 1.0 15.71761805077675 -8.965506728697633 0.7275079096856388 1.0011756709080684 0.8657433726444531 0.17997097633496695 0.07690839185845309 2.436414109729554 2.2436038523410837 0.08140567770765195 0.027552856375256535 1.0826629408685747e-09 8.965506728697633 -0.13543229826361525 SGSS(ph)QELDVKPSASPQER ddPTM_PC-9_AZD4547_30min_R2 2 SGSSQELDVKPSASPQER 18 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.013)GS(0.176)S(0.811)QELDVKPSASPQER;S(0.01)GS(0.045)S(0.945)QELDVKPSASPQER 140.75 0.00019312 31361000.0 32269.0 30836.0 42712.0 48540.0 50219.0 47625.0 42273.0 49464.0 40260.0 49562.0 True False 42529.87076310376 40803.13396915421 42145.61097247498 37349.852935524264 43246.95869303864 44647.00122129818 46035.21510634786 41820.475369642896 42388.06140758102 47826.849465498744 0.8892467565479907 0.8531428355653806 0.8812123617483504 0.7809390196706902 0.9042401742192127 0.9335133240065407 0.9625391515608125 0.8744141802568719 0.8862816991146125 1.0 15.545533138253878 -6.505996266301825 24.053383353267133 0.9247195613638725 0.852072324178904 0.4335579027143891 0.042982635964283346 463.60454267644155 660523.4931841104 0.013434598753646736 0.014855826749522457 3.1189163977949884e-07 6.505996266301825 -0.07264723718496846 SGSS(ph)QELDVKPSASPQER ddPTM_PC-9_Lapatinib_30min_R1 1 SGSSQELDVKPSASPQER 18 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.016)GS(0.293)S(0.683)QELDVKPS(0.007)AS(0.001)PQER 93.34200000000001 0.0050473 10937000.0 14471.0 13131.0 14520.0 14719.0 19720.0 17444.0 17276.0 16605.0 21529.0 16130.0 True False 14264.640886343615 13100.595976266235 13326.221648820858 15801.484361144612 18560.1083710117 16697.9607839501 18170.466747882783 17376.5289195328 19104.177309579478 18918.049008125996 0.7540228318584241 0.6924919145012812 0.7044183912990583 0.8352597223084313 0.9810794106220705 0.8826470835749349 0.9604831206472666 0.9185159057400129 1.0098386626112204 1.0 14.207475692780998 -5.9874422627184005 2.9537507965291114 0.9507377829244416 0.714284223202633 0.8839140998010344 0.03928242466039756 0.07923610535796359 1.4141759702813732 0.011549448725505186 0.01729189341262458 1.0293373633581922e-06 5.9874422627184005 -0.2364535597218086 SGSS(ph)SPDSEITELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSSSPDSEITELK 14 0 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 1 SGSS(0.653)S(0.347)PDSEITELK 292.12 2.6711999999999993e-85 10927000.0 54902.0 87401.0 58425.0 51521.0 66189.0 46334.0 74271.0 50977.0 44853.0 44576.0 True False 64195.82423607199 96077.59366691402 59818.07357804638 48634.44540333568 53219.740591712114 43904.1634736547 67235.51320452495 49638.907764596166 45508.89027146067 52657.27593657817 1.2191254312773634 1.8245834399529601 1.1359887596557952 0.9236035198993642 1.0106816132268481 0.8337720228166389 1.2768513374202115 0.9426789913018402 0.8642469528099553 1.0 15.684345269440051 -5.4583249523436965 6.239625178177641 0.9869809917210739 1.51907460201552 0.5944774433353557 0.17693419515815084 0.13990897345289155 10.550759869310188 0.04398942845042423 0.09179420850565873 3.4807677594339263e-06 5.4583249523436965 0.532093610294446 SGSS(ph)SPDSEITELK ddPTM_PC-9_Lapatinib_30min_R1 1 SGSSSPDSEITELK 14 0 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 1 S(0.002)GS(0.216)S(0.47)S(0.311)PDS(0.001)EITELK 116.9 0.00013785 1684700.0 7099.1 15503.0 10905.0 11566.0 14143.0 13700.0 14867.0 14801.0 14048.0 13333.0 True False 6997.8655321845 15467.103756001477 10008.432994517316 12416.602223044953 13311.136546207834 13114.082936259818 15636.740515210324 15488.708493707001 12465.766308001881 15637.591284894239 0.44750277742227285 0.9890975837782989 0.6400239533172455 0.79402268526095 0.8512267844643223 0.8386255080683618 0.9999455945824126 0.9904791736479865 0.7971666531560836 1.0 13.932730685739415 -3.586723070682836 0.3057094038982424 0.9665403362887005 1.0291856524501173e-12 0.4236005836750284 0.13015703402261852 16.893468671877702 0.7237232963580584 0.13281716895459128 6.970152438289108 0.0002589863824002687 3.586723070682836 -0.9665403362876713 SGSS(ph)SPDSEITELKFPSINHD ddPTM_PC-9_AZD4547_30min_R2 2 SGSSSPDSEITELKFPSINHD 21 1 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 1 S(0.126)GS(0.126)S(0.346)S(0.346)PDS(0.054)EIT(0.001)ELKFPSINHD;S(0.017)GS(0.087)S(0.447)S(0.447)PDS(0.001)EITELKFPSINHD 132.62 1.5401e-05 235339300.0 29210.2 23262.2 67031.0 127046.0 95034.0 90176.0 48536.2 96090.0 64341.0 73485.0 True False 38498.43599009616 30781.251232885534 66142.12514272262 97757.50754113347 81840.16950624713 84537.28046470929 52855.82777292175 81241.49842853379 67741.93390524502 70912.31251709336 0.5429019957685929 0.43407484737528107 0.9327311829913756 1.3785688841774704 1.1541038023054122 1.192138254472122 0.7453688350690988 1.145661388619227 0.9552915636324211 1.0 16.113748524153138 -5.363892912452795 4.223435933074437 1.0853662099342718 0.48906535453215483 0.678790309980323 0.1601833624974646 0.12339850073676309 3.742042821218742 0.044041974642866896 0.0986188101461454 4.32620492662221e-06 5.363892912452795 -0.596300855402117 SGSS(ph)SPDSEITELKFPSINHD ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SGSSSPDSEITELKFPSINHD 21 1 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 1 S(0.107)GS(0.107)S(0.387)S(0.387)PDS(0.011)EITELKFPSINHD;S(0.109)GS(0.082)S(0.405)S(0.405)PDSEITELKFPSINHD;S(0.087)GS(0.087)S(0.47)S(0.339)PDS(0.016)EITELKFPSINHD 159.59 3.3056e-06 192070000.0 27593.1 33936.0 73402.5 83981.9 111071.0 110108.0 94152.0 106383.7 97103.1 64645.4 True False 32264.066841433065 37304.94180478928 75152.69398053135 79276.66641599346 89307.43487984475 104333.74264594405 85233.24095854971 103591.24059784759 98523.04913648314 76365.09928729529 0.4224975432828485 0.48850773655702734 0.9841235679901008 1.0381269343701693 1.1694797193133832 1.3662490276274917 1.1161282019406709 1.356525972789272 1.2901580703225017 1.0 16.2206258216164 -5.325907405615573 1.1757997677603622 1.2367694984422384 0.2916395903524852 0.8679050192313256 0.11372613007952573 0.22638275479216058 0.47457442302649194 0.0358780943769216 0.2084911586525864 4.72163698878498e-06 5.325907405615573 -0.9451299080897532 down SGSS(ph)SPDSEITELKFPSINHD ddPTM_PC-9_Lapatinib_30min_R1 2 SGSSSPDSEITELKFPSINHD 21 1 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 1 S(0.089)GS(0.089)S(0.367)S(0.367)PDS(0.089)EITELKFPSINHD;S(0.021)GS(0.093)S(0.407)S(0.407)PDS(0.071)EITELKFPSINHD 144.43 8.2714e-05 161095300.0 79826.0 55367.0 113299.0 66305.0 108803.0 111787.0 69355.0 82864.0 138877.0 72926.0 True False 78687.6666017046 55238.80111323834 103983.99356678737 71181.2908869958 102403.42145492835 107006.13059822467 72945.86254337874 86714.16394990459 123235.20982035718 85531.16193221294 0.9199882805762407 0.6458324646287095 1.215743960653768 0.8322263988814975 1.1972644722877421 1.2510777146115653 0.8528571446415216 1.013831239877569 1.440822351016654 1.0 16.384162518546297 -5.262872520816116 24.999877111162963 1.0913831016684856 0.7829103694135439 0.3144837184428003 0.18716019614917184 143.04394222418472 2495327.9827929675 0.047639643269115045 0.10860582647728638 5.459180818206005e-06 5.262872520816116 -0.30847273225494176 SGSSGPETFNVGSMPS(ph)PQQQVMVGQMHR ddPTM_PC-9_AZD4547_30min_R2 3 SGSSGPETFNVGSMPSPQQQVMVGQMHR 28 0 Q9Y4G6 Q9Y4G6 TLN2 Talin-2 1 SGSSGPETFNVGSMPS(1)PQQQVMVGQMHR;SGSSGPETFNVGS(0.003)MPS(0.997)PQQQVMVGQMHR;SGSSGPETFNVGS(0.001)MPS(0.999)PQQQVMVGQMHR 124.1 4.4699e-12 9649400.0 30408.0 25730.0 34581.0 57676.0 43362.0 34482.1 27742.1 32638.8 26820.8 33405.2 True False 40077.11147430842 34046.719322426296 34122.433345176 44379.68928531721 37341.934782603006 32325.928835966977 30211.093156431114 27595.223425010146 28238.492732251576 32235.69411575154 1.2432526295354465 1.0561807417632065 1.058529505294646 1.3767251024891587 1.1584033105822398 1.0027992175348055 0.937193815276615 0.8560455787277778 0.8760007658235353 1.0 14.976371428231623 -6.9209386549243 2.643082164453625 0.9072275368097453 1.1772903018745018 0.6424505354945966 0.09280458465448475 0.1876138477920175 2.6580750697323645 0.03885579862599924 0.032750363476838094 1.1996687470999093e-07 6.9209386549243 0.27006276506475646 SGSSQELDVKPS(ph)ASPQER ddPTM_PC-9_Lapatinib_30min_R1 1 SGSSQELDVKPSASPQER 18 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.001)GSS(0.001)QELDVKPS(0.862)AS(0.136)PQER 52.91 0.024459 28063000.0 136220.0 114010.0 120450.0 110210.0 119680.0 112900.0 112340.0 96305.0 134020.0 71046.0 True False 134277.4778203116 113746.01684975345 110547.06595044579 118315.21104978236 112640.65769993294 108071.53018275437 118156.4155161584 100779.68187868735 118925.25630683453 83326.20643715552 1.6114675509868968 1.3650689466529415 1.3266782525833598 1.4199039666952256 1.3518035023577646 1.2969692825781256 1.417998257310223 1.209459618861867 1.427225135906406 1.0 16.346482680073407 -13.826427676665675 0.14209536424496852 1.510506478170104e-13 1.504932526900082 0.6244810391174521 0.09276085945305587 72.45162402368949 0.7516114110811127 21.35029352428338 0.5422118759200498 1.49132508608316e-14 13.826427676665675 1.504932526899931 SGSSS(ph)PDSEITELK ddPTM_PC-9_AZD4547_30min_R2 4 SGSSSPDSEITELK 14 0 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 1 SGSS(0.021)S(0.979)PDSEITELK;SGSS(0.022)S(0.978)PDSEITELK;SGSS(0.015)S(0.985)PDSEITELK;SGSS(0.013)S(0.987)PDSEITELK 294.52 1.4984999999999997e-98 171648000.0 228268.0 252308.0 228626.0 207457.0 227993.0 271977.0 278216.0 298597.0 291480.0 247274.0 True False 300852.47573064483 333861.62684814323 225594.26985842528 159630.99382869925 196340.10739564587 254970.23519506594 302976.68502419186 252455.69472645302 306887.0377317862 238617.0125243475 1.2608173765478985 1.3991526560331795 0.9454240813420903 0.6689841270743895 0.8228252684858844 1.0685333476340033 1.26971954689642 1.0579953711418355 1.286107115688043 1.0 17.864337380041384 -5.2620653595192195 24.996914850265945 1.0088152462993154 1.3299845518266664 0.33495548762272065 0.1773946815978953 66.34648269976528 2649508.2021241994 0.05194682070264571 0.11959933615647775 5.469336454535063e-06 5.2620653595192195 0.321169305527351 SGSSS(ph)PDSEITELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SGSSSPDSEITELK 14 0 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 1 SGSS(0.079)S(0.92)PDSEITELK;SGS(0.024)S(0.23)S(0.744)PDS(0.002)EITELK;SGSS(0.019)S(0.981)PDSEITELK;SGSS(0.085)S(0.915)PDSEITELK;SGSS(0.027)S(0.971)PDS(0.001)EIT(0.001)ELK 318.07 4.726299999999998e-134 160629000.0 643748.0 1049346.0 688265.0 635750.0 765523.0 558416.0 758701.0 618982.0 498126.0 515372.0 True False 752721.8217974384 1153518.1359938825 704675.8478595467 600130.9886293098 615524.2635028367 529131.6819248146 686831.3487604341 602734.378365642 505410.15038819355 608804.8639174915 1.236392588840176 1.8947255588125747 1.1574740768744056 0.9857526182817139 1.0110370333477754 0.8691318241447646 1.1281633729744924 0.9900288484674916 0.8301677275309834 1.0 19.215620359430723 -5.464736794587173 5.714592404463126 0.982500563363995 1.5648458264624059 0.664265176060497 0.1661650638008245 0.1107408000723809 7.621632007471128 0.04085332180179943 0.08511631799195057 3.4297558490582716e-06 5.464736794587173 0.5823452630984108 SGSSS(ph)PDSEITELK ddPTM_PC-9_Lapatinib_30min_R1 4 SGSSSPDSEITELK 14 0 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 1 SGSS(0.207)S(0.793)PDSEITELK;SGSS(0.001)S(0.999)PDSEITELK;S(0.003)GS(0.009)S(0.087)S(0.901)PDSEITELK;S(0.002)GS(0.015)S(0.111)S(0.869)PDS(0.002)EITELK 307.15 1.7393999999999996e-115 176585000.0 192150.0 412012.0 369103.0 364724.0 498342.0 467351.0 544260.0 565710.0 437596.0 486930.0 True False 189409.9057640052 411058.0115279415 338756.7761187832 391547.01964359655 469030.5033380683 447363.48717839207 572439.119715367 591994.9518258905 388309.33038983395 571095.201706558 0.3316608250218296 0.7197714326781416 0.5931704120547739 0.6856072656074994 0.8212825146079009 0.7833431025888007 1.0023532293824096 1.036595912654982 0.6799380019819469 1.0 19.123371737680635 -4.654022094632944 0.39011822070943775 0.9539891510864202 6.542190000231041e-20 0.6548239331093879 0.12065160874249424 4.122204446043038 0.46066226910710567 0.10135807790321072 1.8883944357594409 2.2180835724326762e-05 4.654022094632944 -0.9539891510864202 SGSSS(ph)PDSEITELKFPSINHD ddPTM_PC-9_AZD4547_30min_R2 2 SGSSSPDSEITELKFPSINHD 21 1 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 1 S(0.01)GS(0.04)S(0.154)S(0.79)PDS(0.006)EITELKFPSINHD;S(0.02)GS(0.02)S(0.126)S(0.815)PDS(0.02)EITELKFPSINHD 170.89 3.6288999999999997e-09 257365000.0 29013.1 26213.8 79987.0 147934.0 113813.0 102518.0 50716.0 108104.0 65094.0 96939.0 True False 38238.66229003083 34686.898211201646 78926.32011742266 113830.10185751642 98012.02950538234 96107.53325364932 55229.62575008959 91399.01078278928 68534.7359479652 93545.19511593538 0.40877206191766113 0.37080363313382786 0.843723934934394 1.216846057314231 1.0477505486402694 1.027391445755587 0.5904057999092381 0.9770572467085432 0.7326376930747386 1.0 16.51337593188844 -5.311965114772304 4.504286862098847 0.9394709610273351 0.3849702687825351 0.6361072289733559 0.16423138250525046 0.12658773352861286 5.610946510182555 0.04593495742311146 0.10544066452893604 4.875676529898333e-06 5.311965114772304 -0.5545006922447999 SGSSS(ph)PDSEITELKFPSINHD ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSSSPDSEITELKFPSINHD 21 1 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 1 S(0.024)GS(0.037)S(0.168)S(0.77)PDS(0.002)EITELKFPSINHD 158.89 3.9272e-06 125370000.0 52432.0 43714.0 114350.0 137880.0 180010.0 190890.0 161240.0 144370.0 143990.0 91445.0 True False 61307.70202079578 48053.63702423854 117076.53767478993 130155.03061299103 144738.33271259718 180879.39235736048 145966.179923491 140580.440472659 146095.58134768266 108023.25462177825 0.5675417041955679 0.4448452992134768 1.0838086492090053 1.2048797369483335 1.3398812433431062 1.6744486452539629 1.35124775155648 1.3013905289640937 1.3524456549583423 1.0 16.720982395308013 -5.44123797175371 1.9821094474963494 1.3566052393604833 0.47107916169948494 0.7878190003013368 0.16471518161079682 0.14491133482833407 1.0844526897438758 0.04752565267696682 0.13979413298367716 3.6204456166038332e-06 5.44123797175371 -0.8855260776609983 SGSSS(ph)PDSEITELKFPSINHD ddPTM_PC-9_Lapatinib_30min_R1 2 SGSSSPDSEITELKFPSINHD 21 1 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 1 S(0.046)GS(0.046)S(0.18)S(0.72)PDS(0.008)EITELKFPSINHD;S(0.042)GS(0.049)S(0.184)S(0.705)PDS(0.019)EITELKFPSINHD 125.08 2.9171e-06 155730600.0 63596.0 40001.0 88698.0 53947.0 73522.0 83270.1 50817.6 64755.2 105347.0 53150.1 True False 62689.1093779219 39908.38014215413 81405.5928241812 57914.44234191647 69197.58050981346 79708.83193508378 53448.686675573525 67763.96299247995 93481.7115069101 62337.02396694347 1.0056480946405966 0.6402034874702558 1.3058947579427205 0.9290536932373891 1.1100558882391958 1.2786756066082392 0.8574147958028392 1.0870580383884596 1.4996178123049677 1.0 15.927801660425166 -5.261508422023642 24.999999996710024 1.123770348637425 0.8229257967041613 0.2820177265397238 0.19771596685079199 7.516049732863933 2722785.5339885647 0.049615605028291605 0.11513492614500336 5.476354808783323e-06 5.261508422023642 -0.30084455193326376 SGSSSPDS(ph)EITELKFPSINHD ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGSSSPDSEITELKFPSINHD 21 1 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 1 S(0.063)GS(0.063)S(0.063)S(0.063)PDS(0.592)EIT(0.154)ELKFPSINHD 66.777 0.015535 0.0 2798.8 967.74 4857.4 3768.9 5612.6 5786.2 3654.0 5605.8 3463.9 2872.3 True False 3272.581561180255 1063.8108316291484 4973.218837792086 3557.7407519386625 4512.851320386219 5482.761485977054 3307.866667330913 5458.6536898360655 3514.552984445023 3393.0252528857104 0.9645025654898913 0.313528710322564 1.4657181916233744 1.0485453207024806 1.3300376460647076 1.615891741835419 0.9749018709830198 1.6087866381759384 1.035816925163158 1.0 11.72835645213432 -5.269119931406537 24.944033876224236 1.279187801152474 0.6390156270570662 0.44874015769184017 0.27463229881888335 400.3996425455134 1300376.0627357394 0.06614831740023416 0.14196835399886543 5.381211586169386e-06 5.269119931406537 -0.6401721740954078 SGST(ph)SPLGFAR ddPTM_PC-9_Lapatinib_30min_R1 1 SGSTSPLGFAR 11 0 O75385 O75385 ULK1 Serine/threonine-protein kinase ULK1 1 S(0.001)GS(0.004)T(0.617)S(0.378)PLGFAR 116.84 0.0029866 10156000.0 79802.0 92931.0 94120.0 74168.0 91522.0 85146.0 86733.0 83645.0 84832.0 64928.0 True False 78664.00884610545 92715.82397916379 86381.81691370648 79622.56213719492 86138.85589917515 81504.5040650203 91223.61035217176 87531.45206108526 75277.32683943736 76150.71828887811 1.033004160875977 1.2175305244980865 1.134353278008707 1.0455917413036915 1.1311627498037116 1.070305125105092 1.197934995256572 1.1494501171877891 0.9885307523150664 1.0 16.21657002449465 -8.266650054104268 24.781453257685044 0.994265348478156 1.124495883909114 0.44740069284493267 0.056931615152069626 366.76350096971413 1744255.9160818127 0.04896471209538022 0.014081911468835267 5.4119022767173905e-09 8.266650054104268 0.13023053543095797 SGSTS(ph)PLGFAR ddPTM_PC-9_AZD4547_30min_R2 3 SGSTSPLGFAR 11 0 O75385 O75385 ULK1 Serine/threonine-protein kinase ULK1 1 SGS(0.001)T(0.137)S(0.862)PLGFAR;S(0.219)GS(0.003)T(0.071)S(0.706)PLGFAR;SGST(0.224)S(0.775)PLGFAR 158.08 2.6155e-07 24122000.0 200590.0 213474.0 252288.0 423747.0 311527.0 254610.0 236892.0 282644.0 229067.0 248756.0 True False 264373.4474688089 282475.2957884037 248942.4962779492 326058.6759758878 268276.8533974438 238689.19645049315 257974.92907938754 238967.86431298166 241175.01397045088 240047.1281554337 1.1013397639884432 1.1767493240139795 1.0370567571079443 1.3583110886657244 1.1176007622292026 0.9943430620671235 1.0746845049208227 0.9955039502003407 1.0046986015774655 1.0 17.87295815060954 -6.620017497846958 5.162188460312851 1.0183667661931246 1.1683492151961203 0.46022360632986326 0.0793819263943579 0.19603233114069732 8.416386570132513 0.026301964398165505 0.026271311597549044 2.39873627131275e-07 6.620017497846958 0.14998244900299573 SGSTS(ph)PLGFAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SGSTSPLGFAR 11 0 O75385 O75385 ULK1 Serine/threonine-protein kinase ULK1 1 S(0.202)GS(0.19)T(0.19)S(0.418)PLGFAR;S(0.013)GS(0.351)T(0.232)S(0.404)PLGFAR;S(0.002)GS(0.037)T(0.216)S(0.744)PLGFAR;S(0.002)GS(0.024)T(0.403)S(0.571)PLGFAR 126.66 0.00039959 23404600.0 199013.0 226551.0 220117.0 251254.0 290224.0 241269.0 250970.0 216693.0 231712.0 187187.0 True False 232701.97021407966 249041.48605660154 225365.42407837065 237177.05295645833 233356.69059041672 228616.42891019996 227196.30473454832 211005.03835521208 235100.34964396388 221122.5213285233 1.0523666644898315 1.1262601591205577 1.0191880172329604 1.0726046878060091 1.055327558624013 1.0338902954644902 1.0274679547317624 0.9542449004627638 1.0632130469183356 1.0 17.754486445562428 -6.909701368816608 1.3147459484010349 1.0057479586681632 1.069973892315273 0.3494035150136362 0.03516790979962427 0.46080346370118713 1.6485525433710513 0.0175419958694516 0.01384456103819169 1.231115023708754e-07 6.909701368816608 0.06422593364710982 SGSTS(ph)PLGFAR ddPTM_PC-9_Lapatinib_30min_R1 1 SGSTSPLGFAR 11 0 O75385 O75385 ULK1 Serine/threonine-protein kinase ULK1 1 SGS(0.001)T(0.205)S(0.794)PLGFAR 142.89 0.00014554 15152000.0 98292.0 85629.0 92485.0 80263.0 90082.0 87373.0 80414.0 80540.0 98669.0 59871.0 True False 96890.33805545475 85430.73131152993 84881.24030242425 86165.808769519 84783.55386802617 83636.26046641084 84577.44345127624 84282.1824257256 87555.85818936763 70219.62257690707 1.3798185535579737 1.2166219096088575 1.2087965897204767 1.2270901723396062 1.2074054339322053 1.191066790124219 1.2044702085751595 1.2002653864084316 1.2468859127443086 1.0 16.099586621454705 -14.522878745280336 0.17484985216369828 0.12535520169177194 1.2747345175669347 0.6765463820815614 0.04928493401048102 81.91672483691086 0.7783949237004498 25.001995734254546 0.1661393881955367 3.0000000000000132e-15 14.522878745280336 1.1493793158751626 SGSYS(ph)YLEER ddPTM_PC-9_Lapatinib_30min_R1 1 SGSYSYLEER 10 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;A0A0U1RQZ1;H0YIM2;H0YIS3 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 SGS(0.217)YS(0.783)YLEER 166.29 0.00097968 17524000.0 41590.0 34967.0 41204.0 38933.0 31478.0 39489.0 50740.0 46499.0 40786.0 20913.0 True False 40996.91897332811 34886.03605986608 37816.366172039605 41796.26269668071 29626.525928129136 37800.14752335507 53367.06892727328 48659.51329294519 36192.2511843796 24527.784185179098 1.6714481285309286 1.4223068743790541 1.541776700517861 1.7040374450920064 1.2078761662470494 1.5411154647306375 2.1757802712370693 1.9838527983439969 1.4755613842300828 1.0 14.582129287744001 -7.0304610534722976 24.751603831118747 1.7575951404675128 1.5029723285412848 0.010779981576266029 0.32302793748026454 1311.1305465488438 1065375.644676284 0.11911129320308189 0.09239822431185364 9.322640698851353e-08 7.0304610534722976 -0.25462281192622793 SGT(ph)PDPR ddPTM_PC-9_AZD4547_30min_R2 1 SGTPDPR 7 0 Q2YD98 Q2YD98 UVSSA UV-stimulated scaffold protein A 1 S(0.023)GT(0.977)PDPR 87.696 0.043445 21642000.0 123900.0 103520.0 84081.0 114950.0 113180.0 113030.0 95000.0 86363.0 126340.0 137620.0 True False 163297.62271990324 136980.81555606585 82966.03100245049 88450.05345979631 97466.91062900727 105962.21623188091 103454.81596061414 73017.58277431014 133018.07447177803 132801.96568826798 1.2296325726323891 1.0314667772132762 0.6247349621104282 0.6660297007005084 0.7339267165502333 0.7978964443991046 0.7790156977303956 0.549823057180551 1.0016273010899353 1.0 17.018916975547313 -5.046173493782258 3.8921097882146514 0.7504635263356083 1.2027032489205745 0.5342834456215417 0.13947846917671713 0.14239916374489203 4.426191175123758 0.03403031207523084 0.12167038172289885 8.991383182259788e-06 5.046173493782258 0.45223972258496614 SGT(ph)PDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGTPDPR 7 0 Q2YD98 Q2YD98 UVSSA UV-stimulated scaffold protein A 1 S(0.007)GT(0.993)PDPR 128.61 0.010903 7097400.0 72228.0 98919.0 75553.0 69020.0 125660.0 108250.0 74330.0 90768.0 99580.0 116820.0 True False 84454.77383197361 108739.02458710388 77354.47005634804 65153.03316585918 101037.82505785783 102573.17943676605 67288.92429740203 88385.43617664563 101036.16911314885 137998.5412533886 0.6119975839230097 0.7879722756448613 0.5605455634078927 0.4721284194318201 0.7321658920461728 0.7432917660225435 0.487606055007844 0.6404809454786559 0.7321538923199876 1.0 17.07429349116761 -8.680835283619485 2.418573447266909 0.99963464132374 0.6301722267285461 0.559164645420015 0.09939075206411364 0.4802455787689417 5.374065247922099 0.09868903626180886 0.026757416221093865 2.0852816251577063e-09 8.680835283619485 -0.3694624145951939 SGT(ph)PDPR ddPTM_PC-9_Lapatinib_30min_R1 2 SGTPDPR 7 0 Q2YD98 Q2YD98 UVSSA UV-stimulated scaffold protein A 1 S(0.096)GT(0.904)PDPR;S(0.13)GT(0.87)PDPR 103.83 0.025524 64149000.0 183578.0 272420.0 187594.0 197149.0 264080.0 164081.0 323100.0 330020.0 234340.0 196335.0 True False 180960.1440559176 271789.22822743485 172170.745453781 211647.9951297845 248547.33360125596 157063.63812149258 339828.537059558 345353.9339972429 207946.16149040154 230271.24315005643 0.7858564603222938 1.1803003471446203 0.7476866980806015 0.9191247340939743 1.0793676631141036 0.6820809927149346 1.475774970468668 1.4997701374817034 0.9030487639088015 1.0 17.812974729444164 -7.263193844054947 24.999687732955596 1.2612959738133316 0.9140786444156836 0.32473350709269533 0.22263376717580138 175.77357926501966 2504600.8903325996 0.08720396838152365 0.06225575169103365 5.455143205559382e-08 7.263193844054947 -0.34721732939764793 SGT(ph)PPRQGSIT(ph)SPQANEQSVTPQR ddPTM_PC-9_Lapatinib_30min_R1 1 SGTPPRQGSITSPQANEQSVTPQR 24 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 S(0.461)GT(0.537)PPRQGS(0.077)IT(0.528)S(0.397)PQANEQS(0.001)VTPQR 68.32600000000001 0.0015948 6092000.0 9849.0 13853.0 11833.0 11642.0 13390.0 12784.0 9596.0 11208.0 13337.0 12818.0 True False 9708.551453914608 13820.92422962579 10860.136416700918 12498.191516573514 12602.426525752873 12237.258120959532 10092.833926411395 11728.764596815623 11834.846615163797 15033.574221088607 0.6457913009333315 0.9193372132515399 0.7223921774681281 0.8313519681195612 0.8382854496487336 0.813995257614354 0.6713529183401706 0.7801713966571499 0.7872277371380028 1.0 13.875900429256998 -8.87063451812033 4.6733062852549745 0.9999999780241994 0.7822311363056856 0.42326579436482614 0.07736719757747541 29.399951155103214 394.783102283193 0.07112699808980429 0.01852768276603117 1.346993443757324e-09 8.87063451812033 -0.21776884171851374 SGT(ph)PPRQGSITSPQANEQSVTPQR ddPTM_PC-9_AZD4547_30min_R2 2 SGTPPRQGSITSPQANEQSVTPQR 24 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.197)GT(0.758)PPRQGS(0.041)IT(0.003)S(0.001)PQANEQSVTPQR;S(0.059)GT(0.813)PPRQGS(0.12)IT(0.008)S(0.001)PQANEQSVTPQR 85.01299999999999 2.9649e-05 16307000.0 9210.7 6092.7 11693.2 18704.6 12945.199999999999 15311.1 11641.5 11890.099999999999 8179.4 11457.900000000001 True False 12139.511005538434 8062.046125757739 11538.140527798845 14392.54345318927 11147.982430417243 14353.694496575721 12677.570947426208 10052.758252316657 8611.74638542394 11056.762408513341 1.0979263691323793 0.7291507068606475 1.043536986823092 1.3016960048004185 1.0082501566492617 1.2981824123781345 1.1465897953694744 0.9091954661679594 0.7788669112391507 1.0 13.432641383479647 -7.844918902830741 6.074997826680578 0.8768969586001926 1.0864830520121254 0.23366496021994132 0.1599042703457737 0.32381105954642786 18.468703566447797 0.09464837023778684 0.04495248636547822 1.4291608052705201e-08 7.844918902830741 0.2095860934119328 SGT(ph)PPRQGSITSPQANEQSVTPQR ddPTM_PC-9_Lapatinib_30min_R1 2 SGTPPRQGSITSPQANEQSVTPQR 24 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.174)GT(0.823)PPRQGS(0.003)ITSPQANEQSVTPQR;S(0.161)GT(0.798)PPRQGS(0.04)IT(0.001)SPQANEQSVTPQR 92.01 7.2560000000000005e-06 21482400.0 9920.0 11930.0 9090.5 8419.400000000001 9788.1 14106.1 4841.4 6509.2 15886.0 8310.5 True False 9778.538980894806 11902.376817977021 8343.114180344766 9038.59076229506 9212.383202145014 13502.81498592516 5092.064002847865 6811.641195002879 14096.751393003831 9746.958851954814 1.00323999817991 1.221137484907913 0.8559710066562456 0.9273241940979686 0.9451546212588569 1.3853362049658275 0.5224259258903734 0.6988478456166624 1.4462717661085271 1.0 13.25073643854012 -7.255002087723241 24.99896036980007 0.8917903741700824 1.0438216944337237 0.058069957448909304 0.26478870497777374 1588.441426002805 6168659.313446193 0.1033280352093659 0.0780788177790314 5.5590158495588735e-08 7.255002087723241 0.1520313202636413 SGT(ph)PTQDEMMDKPTSSSVDTMSLLSK ddPTM_PC-9_AZD4547_30min_R2 3 SGTPTQDEMMDKPTSSSVDTMSLLSK 26 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 S(0.174)GT(0.772)PT(0.052)QDEMMDKPT(0.001)SSSVDTMSLLSK;S(0.074)GT(0.62)PT(0.138)QDEMMDKPT(0.041)S(0.049)S(0.049)S(0.019)VDT(0.009)MS(0.002)LLS(0.001)K;S(0.226)GT(0.691)PT(0.079)QDEMMDKPT(0.001)S(0.001)S(0.001)S(0.001)VDT(0.001)MS(0.001)LLSK 74.28 5.6732e-05 31411700.0 75883.0 76918.0 67544.0 93517.0 92445.0 91345.0 87960.0 87247.0 79467.0 80582.0 True False 100012.21553554804 101780.2392865289 66648.32242753444 71958.10047324726 79610.6074668542 85633.18270991051 95788.26959890123 73764.98088660918 83667.46338490413 77760.84870725196 1.286151285617603 1.3088879684132986 0.8570935571761427 0.925376994586949 1.023787790261473 1.1012377582489576 1.2318315860918327 0.9486133718050568 1.075958721848432 1.0 16.24675634462305 -5.2380207129707665 24.51848527893104 1.0258052451794353 1.2975197476337503 0.560550952296339 0.09802490428283898 491.7741671619874 514867.0193582113 0.02695288723289049 0.07120433131665971 5.780684767100466e-06 5.2380207129707665 0.27171450245431505 SGT(ph)PTQDEMMDKPTSSSVDTMSLLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGTPTQDEMMDKPTSSSVDTMSLLSK 26 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 S(0.122)GT(0.601)PT(0.272)QDEMMDKPT(0.002)S(0.002)S(0.001)SVDTMSLLSK 58.498000000000005 0.00073755 20289000.0 29961.0 31184.0 23817.0 33131.0 36942.0 28328.0 33623.0 38944.0 28921.0 27113.0 True False 35032.80554327626 34279.74143212364 24384.887606475502 31274.777482151232 29703.480290365904 26842.4298114061 30437.986030560292 37921.76126457881 29343.91491184344 32028.372273610075 1.0938053686899882 1.0702929621049957 0.7613526968577027 0.9764710243461304 0.9274114849364425 0.8380828592255074 0.950344456175808 1.1840052607301752 0.916185020617532 1.0 14.967062859758146 -11.284294127573158 6.259258348713091 1.0010749085234751 0.9665239454538118 0.006101617122337255 0.11716806649735792 0.0018735856680733678 7.141546906304443e-05 0.12093805772525529 0.028425273409580003 5.196439465139315e-12 11.284294127573158 -0.03455096306966332 SGT(ph)PTQDEMMDKPTSSSVDTMSLLSK ddPTM_PC-9_Lapatinib_30min_R1 1 SGTPTQDEMMDKPTSSSVDTMSLLSK 26 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 S(0.126)GT(0.428)PT(0.428)QDEMMDKPT(0.011)S(0.004)S(0.001)SVDTMSLLSK 68.192 0.00023222 8622700.0 52192.0 42952.0 44013.0 44794.0 46410.0 49908.0 43756.0 44507.0 43359.0 37547.0 True False 51447.73250915938 42852.547282963 40394.42103509316 48088.30018840356 43680.255045570666 47773.55118123029 46021.471580247686 46574.957700791674 38475.45282948843 44036.94892176735 1.1682855821950213 0.9731043664966784 0.9172847352993229 1.0919989092303723 0.9919001228529625 1.0848515247071522 1.0450649444857292 1.0576336199751977 0.8737084146733453 1.0 15.426426895501697 -8.245591492611391 24.638519613580804 0.9368541976391278 1.0364858702192632 0.2510114857256991 0.07176470459540932 830.7874380210498 1291621.7137440392 0.04778527901294497 0.01793247443298184 5.6807870208363e-09 8.245591492611391 0.09963167258013539 SGTAETEPVEQDS(ph)SQPSLPLVR ddPTM_PC-9_AZD4547_30min_R2 1 SGTAETEPVEQDSSQPSLPLVR 22 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0;H7C3N7 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SGTAETEPVEQDS(0.709)S(0.291)QPSLPLVR 149.07 2.5428e-05 2474900.0 13990.0 13643.0 17657.0 16721.0 23068.0 18750.0 17145.0 21196.0 14369.0 15600.0 True False 18438.528989922877 18052.832946593946 17422.856643121144 12866.231786874754 19865.40638266423 17577.559535944176 18670.871785734013 17920.645235624932 15128.516005105099 15053.848748270442 1.2248381990712711 1.1992171070981472 1.1573689183719797 0.854680553924987 1.3196230887431093 1.1676455523019444 1.2402723116159338 1.1904361160586165 1.0049600110963806 1.0 13.877844760898737 -8.267440245775902 23.285035291707647 1.0024799091813552 1.1667017698420363 0.25299143595324514 0.11456679349677408 295.869591546496 1148009.8849648265 0.10193926708859026 0.029237763211575472 5.402064362152468e-09 8.267440245775902 0.16422186066068112 SGTAETEPVEQDS(ph)SQPSLPLVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGTAETEPVEQDSSQPSLPLVR 22 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0;H7C3N7 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SGTAETEPVEQDS(0.582)S(0.396)QPS(0.022)LPLVR;SGTAETEPVEQDS(0.609)S(0.364)QPS(0.027)LPLVR 144.27 6.966700000000001e-07 5287300.0 36299.0 38956.2 40736.0 43835.0 46890.0 42363.0 41836.0 40981.0 35232.0 31492.0 True False 42443.70376207019 42823.514083443326 41707.300732140284 41379.06706498749 37702.24110268144 40141.40970420067 37872.99121358951 39905.29217295868 35747.20134760447 37201.25030946517 1.1409214316453007 1.1511310433710793 1.1211263165939516 1.11230312746933 1.0134670418076996 1.0790338865032025 1.018056944283763 1.0726868543664383 0.9609139760151892 1.0 15.183063489725555 -5.955873821705173 0.4327113226998628 0.9980612626541272 1.193398028527013 0.7357443390305465 0.03198169337175389 1.0415463599941597 0.30881165999184673 0.027481660914370872 0.09538792136590943 1.1069453450242065e-06 5.955873821705173 0.19533676587288573 SGTAETEPVEQDS(ph)SQPSLPLVR ddPTM_PC-9_Lapatinib_30min_R1 1 SGTAETEPVEQDSSQPSLPLVR 22 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0;H7C3N7 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SGTAETEPVEQDS(0.493)S(0.493)QPS(0.014)LPLVR 110.36 9.6926e-06 2821700.0 14950.0 13972.0 16041.0 12145.0 15620.0 13286.0 13482.0 11566.0 14452.0 11166.0 True False 14736.810258505775 13939.648692437115 14722.170900050645 13038.183814532329 14701.262310101556 12717.788751178692 14180.031992067372 12103.39858375889 12824.263573693273 13096.028222240227 1.1252885232393668 1.0644180400256176 1.1241706760412165 0.9955830571890747 1.1225741164130398 0.9711180012258073 1.0827734753951006 0.9242037645585085 0.9792483152956687 1.0 13.6768417155183 -6.871375661400902 0.6642658047687185 0.9695436993656203 1.0992412369477915 0.41519464683340745 0.05353570063754433 0.7082319916839859 0.674318550367172 0.03991060662373631 0.03772460319500224 1.3446966985057776e-07 6.871375661400902 0.12969753758217117 SGTAETEPVEQDSS(ph)QPSLPLVR ddPTM_PC-9_AZD4547_30min_R2 1 SGTAETEPVEQDSSQPSLPLVR 22 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0;H7C3N7 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SGTAETEPVEQDS(0.214)S(0.786)QPSLPLVR 176.23 3.8976e-13 2579000.0 11935.0 10226.0 12593.0 17613.0 18052.0 16743.0 11094.0 16707.0 13393.0 14487.0 True False 15730.081736578231 13531.35451967087 12426.00859187997 13552.594968137379 15545.791400201782 15696.057563216717 12081.344508074251 14125.31703866699 14100.926637648596 13979.814539499625 1.125199600619398 0.9679208891819242 0.8888536079481303 0.9694402547218958 1.1120169982425394 1.1227657934136315 0.8641991976316071 1.0104080421636676 1.0086633551401396 1.0 13.771057601155578 -4.754465530945237 24.811268695244447 0.9937652583882544 1.1251998499226954 0.20510590926488947 0.07759889224375133 398.02070274915684 1415925.419267764 0.02065491709422771 0.19980634223050914 1.760088352830098e-05 4.754465530945237 0.13143459153444104 SGTAETEPVEQDSS(ph)QPSLPLVR ddPTM_PC-9_Lapatinib_30min_R1 1 SGTAETEPVEQDSSQPSLPLVR 22 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0;H7C3N7 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SGTAETEPVEQDS(0.008)S(0.992)QPSLPLVR 212.18 4.2086e-26 2811400.0 18083.0 16841.0 21311.0 14544.0 23460.0 17097.0 18366.0 15279.0 17110.0 11664.0 True False 17825.133103983942 16802.00569920795 19558.891842838933 15613.61427736173 22080.12892413461 16365.801165053585 19316.901614471833 15988.9181187318 15182.891623712423 13680.106858696938 1.3029966277384641 1.2282071969727568 1.4297323876826766 1.1413371575701978 1.614031904297405 1.1963211496881878 1.412043181679636 1.1687714346008247 1.10985182941463 1.0 13.73979187906493 -8.149901550824925 1.8232962365808165 1.0193826283286829 1.3306410488039804 0.4276030213598555 0.1303246639946948 0.32072662387740486 1.9046297306966078 0.11069438695163215 0.03402294493911417 7.081062851080899e-09 8.149901550824925 0.3112584204752975 SGTLKS(ph)PPKGFDTTAINK ddPTM_PC-9_Lapatinib_30min_R1 1 SGTLKSPPKGFDTTAINK 18 2 B1ALK7;A0A2R8YG42;Q14155-1;Q14155-5;Q14155-6;Q14155-2;Q14155-3;Q14155;E7EUY6;E7EU80 B1ALK7 ARHGEF7 Rho guanine nucleotide exchange factor 7 1 S(0.029)GT(0.082)LKS(0.839)PPKGFDT(0.025)T(0.025)AINK 46.873000000000005 0.029916 26081000.0 130650.0 92352.0 93292.0 105670.0 111370.0 89117.0 85483.0 78602.0 108940.0 87587.0 True False 128786.90704172455 92138.16461808984 85621.89187753433 113441.32430478667 104819.43556184437 85305.6736518734 89908.89146846862 82254.13587070878 96670.03001094285 102726.29624765857 1.2536897731739256 0.8969287123518769 0.8334953658906583 1.10430657434875 1.0203758861230579 0.830417106114811 0.875227617003839 0.8007115887095325 0.9410446355223894 1.0 16.648446009646882 -6.7522499513487055 24.968354422481013 0.8761338772885677 1.008951111226834 0.23117809329342975 0.11823262725883023 298.98985104742445 812376.1925385026 0.039407596678381555 0.03888139061795821 1.7690904930954788e-07 6.7522499513487055 0.13281723393826617 SGTNS(ph)PPPPFSDWGR ddPTM_PC-9_AZD4547_30min_R2 3 SGTNSPPPPFSDWGR 15 0 D6RAU6;D6REP2;D6RAJ6;Q9UKT5-2;Q9UKT5 D6RAU6 FBXO4 F-box only protein 4 1 S(0.397)GT(0.138)NS(0.465)PPPPFSDWGR;S(0.085)GT(0.089)NS(0.825)PPPPFS(0.001)DWGR;S(0.022)GT(0.101)NS(0.876)PPPPFS(0.001)DWGR 175.27 6.2535e-05 76975000.0 235439.0 228686.0 309537.0 439945.0 355266.0 341129.0 269226.0 336811.0 251120.0 314980.0 True False 310303.70456457854 302604.27730153064 305432.3371321174 338522.4773324929 305943.4482375411 319798.1497033127 293186.5924401301 284764.59909681446 264393.69052835915 303952.64607245015 1.020894894563986 0.9955638854001024 1.004868163112864 1.1137342665271703 1.006549711577824 1.0521314877024812 0.9645798325119569 0.9368715909416296 0.8698515836093043 1.0 18.213487052717944 -7.464692822883056 3.1202899139011016 0.9286219120736628 1.031858013757823 0.5111787907305867 0.04323047544972759 0.20371801382485347 3.919648113743881 0.02106549055938936 0.012562111316594219 3.430103124583733e-08 7.464692822883056 0.1032361016841602 SGTNS(ph)PPPPFSDWGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGTNSPPPPFSDWGR 15 0 D6RAU6;D6REP2;D6RAJ6;Q9UKT5-2;Q9UKT5 D6RAU6 FBXO4 F-box only protein 4 1 S(0.048)GT(0.189)NS(0.763)PPPPFSDWGR;S(0.018)GT(0.013)NS(0.969)PPPPFSDWGR 97.2 0.0024964 18317700.0 48866.0 56425.0 52230.0 63042.0 73663.0 64687.0 58682.0 52223.0 57378.0 48850.0 True False 57138.04865250621 62026.50110016606 53475.361283378064 59509.96112492165 59229.26394427005 61294.6998450447 53123.2161391113 50852.2015848423 58217.04470148867 57706.11830361276 0.9901558159202853 1.0748687127736127 0.9266844288854234 1.0312591259702866 1.0263948725964112 1.0621871934367706 0.9205820405318348 0.8812272091720063 1.0088539380726969 1.0 15.816436668581908 -7.27199230505185 24.94473072147603 0.942768062289699 1.0179026183293267 0.27492001580782044 0.05144876488753649 836.5854671985628 1977491.581535401 0.02090900534157296 0.014266250330698086 5.345738310380857e-08 7.27199230505185 0.07513455603962771 SGTNS(ph)PPPPFSDWGR ddPTM_PC-9_Lapatinib_30min_R1 1 SGTNSPPPPFSDWGR 15 0 D6RAU6;D6REP2;D6RAJ6;Q9UKT5-2;Q9UKT5 D6RAU6 FBXO4 F-box only protein 4 1 S(0.012)GT(0.314)NS(0.675)PPPPFSDWGR 125.41 2.651e-05 6078600.0 18542.0 20709.0 18403.0 15092.0 15116.0 14200.0 16327.0 15744.0 16916.0 10628.0 True False 18277.587679813645 20661.049582857162 16889.976377634317 16201.916025436132 14226.906599199427 13592.69910181675 17172.33217137546 16475.523716297757 15010.741946622995 12465.03563908017 1.4663084975473364 1.6575202976621253 1.3549882139671665 1.2997889853311095 1.1413450399287643 1.0904661242364322 1.3776400379905094 1.321738998053401 1.2042277600524116 1.0 13.6055993872285 -5.565998469777568 2.3080084327258965 1.214146028383127 1.5618215542194125 0.6019367744361453 0.11504826082362882 0.20991909821685875 2.228925281262463 0.0335291564249383 0.07639696258482599 2.7164488401410438e-06 5.565998469777568 0.3476755258362856 SGTPPRQGS(ph)ITSPQANEQSVTPQR ddPTM_PC-9_Lapatinib_30min_R1 1 SGTPPRQGSITSPQANEQSVTPQR 24 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.152)GT(0.13)PPRQGS(0.666)IT(0.023)S(0.029)PQANEQSVTPQR 62.735 0.0011574000000000003 14906000.0 4625.3 5551.6 3902.8 4913.4 4783.3 6792.1 3911.9 2910.1 4155.7 3035.3 True False 4559.342373823862 5538.74561128929 3581.926849243667 5274.74782662191 4501.955698329627 6501.617716158419 4114.439040926298 3045.31386984236 3687.6413045389686 3559.947560716977 1.2807330153216092 1.5558503367880454 1.006174048395888 1.481692563347638 1.2646129252035747 1.8263240132809673 1.1557583281079695 0.8554378450532655 1.0358695575269299 1.0 11.797640274603545 -7.518224381542627 23.771386114335794 0.9685116252156544 1.3973572048835938 0.48470903739762705 0.20464746375179144 91.70896670495802 468403.5278200901 0.09123923262613422 0.054561319405039964 3.0323241061272114e-08 7.518224381542627 0.42884557966793946 SGTPPRQGSITSPQANEQS(ph)VTPQRR ddPTM_PC-9_Lapatinib_30min_R1 1 SGTPPRQGSITSPQANEQSVTPQRR 25 2 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SGT(0.001)PPRQGS(0.006)IT(0.006)S(0.005)PQANEQS(0.936)VT(0.046)PQRR 52.273 0.043862 7666300.0 9073.8 2984.4 2515.5 3705.3 2208.5 3138.4 1094.2 842.76 3567.7 832.73 True False 8944.40594806888 2977.4898051609903 2308.6853001108047 3977.8001225184535 2078.60037207806 3004.1779479677243 1150.852322038282 881.9177062466401 3165.8680564534657 976.6662709570221 9.158098537901157 3.0486256090766686 2.363842561951643 4.072834540114363 2.128260628926263 3.0759513636361895 1.178347564834585 0.9029877783968734 3.241504442813689 1.0 9.931721864061023 -4.753707951419149 3.7324353076870374 2.3093800816270313 10.106976672719938 0.8157946480482208 0.9788691419030612 0.12306190779779824 2.8993232317508832 0.252870043054735 2.7757143039718764 1.7631613151265727e-05 4.753707951419149 7.797596591092907 SGTPT(ph)QDEMMDKPTSSSVDTMSLLSK ddPTM_PC-9_AZD4547_30min_R2 1 SGTPTQDEMMDKPTSSSVDTMSLLSK 26 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 S(0.104)GT(0.317)PT(0.346)QDEMMDKPT(0.017)S(0.062)S(0.062)S(0.062)VDT(0.022)MS(0.008)LLS(0.001)K 43.903 0.015776 7828900.0 32521.0 27199.0 39005.0 38616.0 39827.0 41593.0 27157.0 35219.0 29481.0 35768.0 True False 42862.00152117809 35990.54484456561 38487.76821458572 29713.677811252655 34297.70851406142 38992.183134854706 29573.920389920004 29776.71280210766 31039.305473345637 34515.77320693187 1.2418091075117514 1.0427274692295623 1.115077677206899 0.8608724374537609 0.9936821727398922 1.129691718075834 0.8568233489256041 0.8626987036792657 0.8992788684540305 1.0 15.074968182804406 -1.522878757344289 0.47023596552338226 0.9272089476161038 8.693400486551205 0.49677139008348414 0.08952096092489012 83.50853970418031 0.9591529120459088 0.055018355810205234 630.415042092929 0.029999999166651768 1.522878757344289 7.766191538935101 SGTPT(ph)QDEMMDKPTSSSVDTMSLLSK ddPTM_PC-9_Lapatinib_30min_R1 1 SGTPTQDEMMDKPTSSSVDTMSLLSK 26 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 S(0.179)GT(0.355)PT(0.418)QDEMMDKPT(0.009)S(0.009)S(0.009)S(0.01)VDT(0.009)MS(0.002)LLSK 50.908 0.012228 7936000.0 24199.0 24729.0 20387.0 23548.0 23611.0 22864.0 24201.0 19951.0 22676.0 19227.0 True False 23853.917822446907 24671.74151984523 18710.85955609579 25279.798473825198 22222.247401012042 21886.160018587198 25454.00936359755 20877.996294706332 20121.990091134012 22550.36133163291 1.0578064569185155 1.0940730020692182 0.8297365741030858 1.1210374016652018 0.9854497262462664 0.9705458682777738 1.128762816225543 0.9258386589761363 0.8923134221759694 1.0 14.460862929978154 SGTPTQDEMMDKPT(ph)SSSVDTMSLLSK ddPTM_PC-9_Lapatinib_30min_R1 1 SGTPTQDEMMDKPTSSSVDTMSLLSK 26 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2;Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 S(0.004)GT(0.015)PT(0.006)QDEMMDKPT(0.235)S(0.235)S(0.235)S(0.235)VDT(0.025)MS(0.01)LLS(0.001)K 44.167 0.010519 27817000.0 76975.0 75670.0 64475.0 71786.0 75539.0 71421.0 56364.0 62178.0 69256.0 59386.0 True False 75877.32238451368 75494.79076415095 59174.11438069734 77065.38191107604 71095.94453538812 68366.49032048274 59282.25212882995 65067.01687194877 61455.65998198876 69650.79097312906 1.0893964206922904 1.0839042846372913 0.8495828052193468 1.1064537937667858 1.0207485592348347 0.9815608604769214 0.8511353755006279 0.934189202489478 0.8823397282838907 1.0 16.087852116102198 -7.021894801606925 4.508580340653727 0.9111254078871963 1.0258298333533975 0.32641725548651634 0.07614059195771425 0.2443459091273663 12.226809747802733 0.02892152131559995 0.023375995996123788 9.508350848839018e-08 7.021894801606925 0.11470442546620119 SGTSEFLNK ddPTM_PC-9_Lapatinib_30min_R1 1 SGTSEFLNK 9 0 P14625;Q96GW1;A0A1W2PRR1 P14625 HSP90B1 Endoplasmin 0 84.615 0.041507 0.0 41444.0 40004.0 26845.0 31819.0 34699.0 28137.0 31733.0 29206.0 26771.0 21175.0 False True 40853.000960101235 39911.37319583846 24637.90772469671 34159.075405072384 32658.073040858777 26933.646100550573 33375.97946923851 30563.017381744954 23755.768068872334 24835.070536086063 1.6449722138191902 1.6070569696126331 0.9920611132912681 1.3754370198159203 1.3149981995583895 1.0845004873819553 1.3439051610802661 1.2306394434167611 0.9565411958204237 1.0 14.600091223844917 -1.5228787452804835 0.5083589688536797 1.1472395745912318 19.6483802513694 0.5202245785572157 0.1631698239113753 93.03383955472518 0.965775214597092 0.08778236671805957 1845.6950235179802 0.02999999999998992 1.5228787452804835 18.501140676778167 SGTSSPQS(ph)PVFR ddPTM_PC-9_AZD4547_30min_R2 4 SGTSSPQSPVFR 12 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 SGTSS(0.008)PQS(0.991)PVFR;SGTSS(0.001)PQS(0.999)PVFR;S(0.001)GTS(0.001)S(0.015)PQS(0.983)PVFR;SGTSS(0.001)PQS(0.999)PVFR 157.37 6.7901e-05 678300000.0 162060.0 156733.0 225104.0 311449.0 259183.0 231682.0 226819.0 262364.0 209582.0 217933.0 True False 213591.70894259494 207393.87716913506 222118.97387965943 239649.2448890833 223199.9142742355 217194.8879150194 247005.45159337443 221821.67232494376 220660.076649867 210303.23200364262 1.0156368350006877 0.9861659052655112 1.0561843095013022 1.139541425996403 1.0613242228743753 1.0327700903391603 1.1745204733187176 1.054770629112831 1.0492471967622685 1.0 17.682111496450382 -5.402098161301407 4.832710535129515 1.0787970329909797 1.0019716888969332 0.2499030261983547 0.04843327792481728 0.2705505298325453 9.419859626252936 0.012591983856228575 0.027133156319376486 3.961884757336845e-06 5.402098161301407 -0.07682534409404651 SGTSSPQS(ph)PVFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SGTSSPQSPVFR 12 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 SGTSS(0.003)PQS(0.997)PVFR;SGTSS(0.013)PQS(0.987)PVFR;SGTSSPQS(0.999)PVFR;SGTSS(0.002)PQS(0.997)PVFR;SGTS(0.001)S(0.023)PQS(0.976)PVFR;SGTS(0.003)S(0.226)PQS(0.771)PVFR 161.21 9.068100000000001e-05 605228000.0 238386.0 244669.0 272359.0 296136.0 347744.0 292152.0 302380.0 314003.0 284726.0 237552.0 True False 278740.04146188195 268958.121358911 278853.07148725906 279544.4600058655 279606.0595011913 276831.03481579776 273736.37735837983 305760.7539636788 288889.5791013295 280618.29713940265 0.9933067241278724 0.958448269769454 0.993709513349136 0.9961733174761455 0.9963928309432065 0.9865038653494377 0.9754758693528666 1.0895966409908977 1.0294752054525436 1.0 18.098249554426957 -7.7379940681465245 24.999992909358525 1.044651969760582 0.9858176409447461 0.5263828817061603 0.023319757625548693 150.1054885329076 160059.35397938685 0.010444355506984446 0.0060253963327226295 1.8281251855981007e-08 7.7379940681465245 -0.058834328815835946 SGTSSPQS(ph)PVFR ddPTM_PC-9_Lapatinib_30min_R1 4 SGTSSPQSPVFR 12 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 SGTSS(0.002)PQS(0.998)PVFR;SGTSS(0.009)PQS(0.99)PVFR;SGTS(0.001)S(0.048)PQS(0.95)PVFR;SGTSS(0.008)PQS(0.992)PVFR 156.2 6.389899999999999e-05 670480000.0 286292.0 240133.0 293278.0 250621.0 255800.0 262193.0 219586.0 237008.0 292056.0 211232.0 True False 282209.423580477 239576.98679222737 269165.81492581905 269052.50438714796 240754.34692214988 250979.61659173525 230955.08863745 248020.25692024318 259161.57779397792 247743.16975105173 1.1391209043787531 0.9670377069647157 1.0864711838324108 1.0860138128429906 0.9717900483959874 1.0130637177361366 0.9322359476934462 1.0011184452409723 1.0460896986762547 1.0 17.91848575747069 -6.262559919635354 24.99424867731942 0.9919655833454708 1.0635314091264454 0.3650968470680134 0.04853252447926583 117.96722727940583 2631316.4044226776 0.014467858687405091 0.017349225310586327 5.463111700974478e-07 6.262559919635354 0.07156582578097459 SGTSTPTTPGSTAITPGT(ph)PPSYSSR ddPTM_PC-9_AZD4547_30min_R2 3 SGTSTPTTPGSTAITPGTPPSYSSR 25 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 SGTSTPTTPGSTAIT(0.001)PGT(0.988)PPS(0.008)YS(0.001)S(0.001)R;SGTSTPTTPGSTAIT(0.036)PGT(0.9)PPS(0.031)Y(0.014)S(0.011)S(0.008)R;SGTSTPTTPGST(0.001)AIT(0.129)PGT(0.745)PPS(0.068)Y(0.007)S(0.029)S(0.022)R 129.72 4.1938999999999995e-07 47851100.0 88006.0 82700.0 120355.0 160424.0 140220.0 96037.0 92020.0 117593.0 97819.0 114576.0 True False 115990.07736148346 109431.15771335617 118759.01406143993 123440.72532609265 120752.87337338206 90031.79120818526 100209.60173363933 99421.70386831652 102989.51263855367 110564.72911422008 1.0490694301042303 0.9897474410696302 1.074113010657808 1.1164566341818727 1.0921464226501836 0.8142903431272096 0.9063433025745192 0.899217179518505 0.9314861390575945 1.0 16.754531704064696 -6.747505061478639 24.99999990966244 0.9037232049437196 1.0636064653603838 0.6828554950957504 0.0523927300610539 136.4503690266062 244809.52883266416 0.017747942641305397 0.01766181020194547 1.7885246846517252e-07 6.747505061478639 0.15988326041666423 SGTSTPTTPGSTAITPGT(ph)PPSYSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SGTSTPTTPGSTAITPGTPPSYSSR 25 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 SGTSTPTTPGSTAIT(0.019)PGT(0.95)PPS(0.009)Y(0.002)S(0.011)S(0.009)R;SGTSTPTTPGS(0.001)T(0.002)AIT(0.026)PGT(0.948)PPS(0.01)Y(0.005)S(0.004)S(0.004)R;SGTSTPTTPGSTAIT(0.316)PGT(0.672)PPS(0.008)YS(0.003)S(0.002)R;SGTSTPTTPGS(0.003)T(0.003)AIT(0.042)PGT(0.94)PPS(0.006)Y(0.002)S(0.002)S(0.002)R 107.13 1.1058e-06 56860000.0 88620.0 86584.0 98519.0 105246.0 116579.0 103237.0 98897.0 99854.0 93586.0 78700.0 True False 103621.61567521597 95179.48730627882 100868.06659538795 99349.40783213556 93736.18181935379 97823.06998164827 89528.76020772435 97232.93830405832 94954.51820268235 92967.68701114286 1.114598190044205 1.0237910651135256 1.0849798444840106 1.068644504624793 1.008266257157918 1.0522265652357625 0.9630094400110618 1.045878857805769 1.0213712017090557 1.0 16.50444174212101 -6.254350615171008 23.336989148301146 1.0166685906334787 1.07034370462411 0.45162745305889473 0.031161163740471988 217.46932392819545 715930.2670934349 0.008841804585120107 0.011132793210232273 5.567361025565893e-07 6.254350615171008 0.053675113990631296 SGTSTPTTPGSTAITPGT(ph)PPSYSSR ddPTM_PC-9_Lapatinib_30min_R1 4 SGTSTPTTPGSTAITPGTPPSYSSR 25 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 SGTSTPTTPGSTAIT(0.03)PGT(0.93)PPS(0.011)Y(0.005)S(0.014)S(0.011)R;SGTSTPTTPGS(0.003)T(0.014)AIT(0.04)PGT(0.931)PPS(0.007)Y(0.003)S(0.001)S(0.001)R;SGTSTPTTPGS(0.001)T(0.093)AIT(0.117)PGT(0.783)PPS(0.002)YS(0.002)S(0.002)R;SGTSTPTTPGSTAIT(0.019)PGT(0.977)PPS(0.003)YSSR 123.3 3.3757e-09 59298500.0 104736.0 86546.0 108466.0 94104.0 89341.0 105988.0 88301.0 86534.0 109718.0 80092.0 True False 103242.44543376987 86345.60805437039 99548.34417086825 101024.72208174154 84086.13803116417 101455.14031009545 92872.79371988882 90554.68554789806 97360.40345823964 93935.79548411815 1.0990745849512202 0.9191981353792756 1.0597487747649832 1.0754656578047708 0.8951447911609023 1.0800477047884116 0.9886837412857269 0.9640061606036887 1.0364569007636764 1.0 16.519387400333123 SGTTPLPPGAATS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 2 SGTTPLPPGAATSPSK 16 0 C9JKK0;A0A2U3TZT0;Q569K4-4;Q569K4-3;Q569K4-2;Q569K4-5;Q569K4 C9JKK0 ZNF385B Zinc finger protein 385B 1 SGTTPLPPGAAT(0.008)S(0.99)PS(0.002)K;SGTTPLPPGAAT(0.055)S(0.714)PS(0.231)K 127.18 0.00014726 0.0 20499.3 22270.0 21515.0 23428.0 26199.0 21404.0 20628.7 17226.8 21931.9 19377.3 True False 20206.9762228888 22218.435183264733 19746.119750301707 25150.973273516956 24658.026329215783 20488.60081516098 21696.753148995707 18027.220017525295 19461.698468854403 22726.64048637074 0.8891316882056108 0.9776383445933956 0.86885343929929 1.1066736101448913 1.084983341202731 0.9015235149888554 0.9546836965193928 0.7932197470337199 0.8563385547690459 1.0 14.47209681637282 -7.2971196130577445 2.2311040046474484 0.8741625036662185 0.9822723364781194 0.14866519945154033 0.08830605187045584 0.511873815543711 4.985585497315462 0.045214815704073215 0.028624796569933983 5.045223232696098e-08 7.2971196130577445 0.1081098328119009 SGVGLSSYLSTEKDAS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 SGVGLSSYLSTEKDASPK 18 1 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 SGVGLSSYLSTEKDAS(0.999)PK;SGVGLS(0.004)S(0.017)Y(0.012)LS(0.003)T(0.006)EKDAS(0.957)PK 84.689 0.00090598 101507000.0 311342.0 229080.0 233909.0 343538.0 333625.0 264162.0 300496.0 211039.0 287507.0 298869.0 True False 410342.2796841013 303125.63009644044 230807.21382657444 264340.62170919083 287306.92753668973 247643.90838048502 327239.56186211295 178427.77174377514 302704.0330628264 288405.68727864296 1.4227953808956944 1.0510390171452333 0.800286624041433 0.9165582835882092 0.9961902285897307 0.8586651349258034 1.134650169176278 0.6186693938923169 1.0495771977283135 1.0 18.137740088834526 -4.810660435933908 3.1669900599483185 0.9159939950231125 1.4805324783847116 0.5498107106915303 0.13617430678071682 0.2209933571778241 3.4753996432654755 0.03237020215096208 0.30185920681569234 1.5464631080478348e-05 4.810660435933908 0.5645384833615991 SGVGLSSYLSTEKDAS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGVGLSSYLSTEKDASPK 18 1 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 SGVGLSSYLST(0.001)EKDAS(0.999)PK;SGVGLSSYLSTEKDAS(1)PK 75.868 0.0026620000000000003 66664000.0 162630.0 109673.0 105741.0 238200.0 213359.0 194002.0 237941.0 275840.0 206864.0 206857.0 True False 190160.0469110847 120560.61063639345 108262.26646497565 224854.42625481926 171552.83556039678 183828.19359899766 215401.50593633985 268599.4922766383 209888.99465176067 244358.53662088845 0.7782009564335772 0.49337589062189363 0.44304679493534455 0.9201824064107531 0.7020537851172086 0.7522888135649586 0.8814977733743996 1.099202409668047 0.8589386626479689 1.0 17.898639980189785 -6.8188985768184684 0.7105351322752724 1.0013369198117656 0.5885354948209671 0.5185573646987749 0.13656076660802344 0.5649064479178727 0.6207369061121409 0.10426180052616071 0.09956978406654461 1.517404693956643e-07 6.8188985768184684 -0.4128014249907985 SGVGNIFIK ddPTM_PC-9_Lapatinib_30min_R1 1 SGVGNIFIK 9 0 A0A087WTT1;P11940;E7EQV3;P11940-2;E5RGH3;Q4VXU2;E5RH24;E5RJB9;Q4VXU2-2;Q96DU9-2;Q96DU9 A0A087WTT1;Q96DU9-2 PABPC1;PABPC1L;PABPC5 Polyadenylate-binding protein;Polyadenylate-binding protein 1;Polyadenylate-binding protein 1-like;Polyadenylate-binding protein 5 0 96.331 0.023678 3241500.0 69585.0 61468.0 69273.0 63427.0 59792.0 56481.0 55009.0 52892.0 55086.0 58689.0 False True 68592.70513967382 61325.67462258265 63577.641341512914 68091.63316626938 56275.152115594916 54065.43929364169 57857.096858895835 55349.555411739166 48881.63459870385 68833.31545182306 0.9965044497628821 0.8909301291102989 0.9236463611288834 0.9892249518901529 0.8175569017154536 0.7854545279238 0.8405391557724753 0.8041099727424683 0.7101449970533014 1.0 16.070819380577284 -6.275908317729782 23.310371947972186 0.8151759917275798 0.9439638627959971 0.39530466830768896 0.07408148579520832 308.57055266881116 497125.13870522863 0.02177693198425537 0.024824695366349406 5.297752709470542e-07 6.275908317729782 0.12878787106841727 SGVGTGPPS(ph)PIALPPLR ddPTM_PC-9_AZD4547_30min_R2 3 SGVGTGPPSPIALPPLR 17 0 Q92630 Q92630 DYRK2 Dual specificity tyrosine-phosphorylation-regulated kinase 2 1 S(0.001)GVGT(0.05)GPPS(0.949)PIALPPLR;SGVGTGPPS(1)PIALPPLR;SGVGT(0.009)GPPS(0.991)PIALPPLR 91.59200000000001 0.0021898000000000004 9417600.0 34537.0 35238.5 42078.0 65421.0 49096.0 41859.0 44411.0 45906.0 36334.0 42597.0 True False 45519.047585773136 46628.65599857438 41520.01822672321 50339.19919437439 42279.867858647594 39241.55011280466 48363.492964493045 38812.28251493668 38254.54106266887 41105.69199551771 1.1073660453334948 1.1343600784937258 1.0100795342710853 1.2246284334506163 1.0285647998155079 0.9546500303919876 1.1765643787183233 0.9442070095588926 0.9306385370386238 1.0 15.32705056044244 -7.311977099440209 0.7040750890253327 0.9605141151794311 1.1101606905861556 0.2819009363339756 0.08302555891507521 0.9546245882578512 0.9311345861697043 0.07197830508880249 0.04542079081612864 4.875541983961862e-08 7.311977099440209 0.14964657540672455 SGVGTGPPS(ph)PIALPPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGVGTGPPSPIALPPLR 17 0 Q92630 Q92630 DYRK2 Dual specificity tyrosine-phosphorylation-regulated kinase 2 1 S(0.019)GVGT(0.04)GPPS(0.941)PIALPPLR;S(0.022)GVGT(0.007)GPPS(0.97)PIALPPLR 127.49 3.4224e-05 6735500.0 26588.4 33484.4 34382.9 33646.3 38954.5 39405.5 43986.3 39251.8 34369.3 27255.7 True False 31089.290975162596 36808.509941309705 35202.7187338744 31761.2068937764 31321.64536221803 37339.00621058186 39819.59923076565 38221.48184071985 34871.88599217253 32196.942653997536 0.9655976130796563 1.1432299748727726 1.0933559472456205 0.986466548550782 0.9728142730449337 1.1597065787221847 1.2367509442956905 1.1871152566088232 1.0830806628729042 1.0 14.974636079462949 -6.781448693780887 24.983334768070524 1.1514891992560838 1.0393025289396842 0.27400365782241654 0.07912171195508982 299.1504736255252 373512.49540750263 0.028326978981335443 0.0250138094881038 1.6540601788298142e-07 6.781448693780887 -0.11218667031639962 SGVGTGPPS(ph)PIALPPLR ddPTM_PC-9_Lapatinib_30min_R1 1 SGVGTGPPSPIALPPLR 17 0 Q92630 Q92630 DYRK2 Dual specificity tyrosine-phosphorylation-regulated kinase 2 1 SGVGTGPPS(1)PIALPPLR 134.82 3.4262e-05 2715300.0 10750.0 9791.2 8449.9 7390.2 8856.8 10619.0 8075.3 6345.4 8300.4 5919.4 True False 10596.70302869144 9768.529077969539 7755.181839557262 7933.6999609845 8335.860437138763 10164.85012409803 8493.399521253641 6640.230449021577 7365.521544913072 6942.560402895291 1.5263393350200083 1.4070499226619215 1.117049242570951 1.1427628282032474 1.2006896524317479 1.4641356407729533 1.2233814368704081 0.956452672165786 1.0609229329630883 1.0 12.761252108752071 -1.5228787452803376 0.17691788264598743 0.9797738769070452 2.964097250774788 0.49259341599173945 0.13279091651644248 59.79182627431749 0.6656948969770085 0.3580570325213144 31.737561333832502 0.029999999999999995 1.5228787452803376 1.9843233738677426 SGVTNMS(ph)SPHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGVTNMSSPHK 11 0 Q9NVG8 Q9NVG8 TBC1D13 TBC1 domain family member 13 1 SGVT(0.002)NMS(0.778)S(0.22)PHK 83.137 0.011595000000000001 5832600.0 50173.0 45240.0 58676.0 77367.0 78128.0 72611.0 64538.0 59058.0 65185.0 57871.0 True False 58666.29793807951 49731.12821925587 60075.05836996917 73032.37781719812 62819.379246540746 68803.15133564001 58424.49342534279 57507.790077123434 66138.2073070958 68362.55419341596 0.8581642191439608 0.727461529283315 0.8787714133676275 1.0683096715574727 0.9189150403714863 1.0064450070279336 0.8546271290572945 0.8412176922825105 0.9674624959151339 1.0 16.060918680210882 -5.518560415187846 24.978568563630347 0.9438160438937184 0.7953887524224714 0.4392421894085292 0.07126910487308002 161.86678323235975 936286.4678250708 0.01962536661523107 0.035098406130614844 3.0299787647570385e-06 5.518560415187846 -0.148427291471247 SGVTNMSS(ph)PHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGVTNMSSPHK 11 0 Q9NVG8 Q9NVG8 TBC1D13 TBC1 domain family member 13 1 SGVT(0.01)NMS(0.286)S(0.704)PHK 89.43 0.0081778 4493800.0 49301.0 45200.0 62454.0 75115.0 82391.0 66518.0 71732.0 69195.0 59425.0 50355.0 True False 57646.68556086457 49687.15728360667 63943.140218113964 70906.55007611567 66247.07499874239 63029.67898175334 64937.02566529312 67378.70456816258 60293.9782039451 59483.96289003933 0.9691130644309777 0.8353034140556034 1.0749643620133005 1.1920280127803837 1.1136963944585399 1.0596079332889865 1.0916728225611698 1.132720506411405 1.013617373062436 1.0 15.860213144144867 -5.331285827279459 6.812594176919807 1.0944803280606057 0.9028855420601426 0.5859691042873021 0.06102805072390709 0.13900579665594695 11.410585823853562 0.015495025022975525 0.032731519813508 4.66352353392424e-06 5.331285827279459 -0.1915947860004631 SGWS(ph)SGR ddPTM_PC-9_Lapatinib_30min_R1 1 SGWSSGR 7 0 A0A087WVC1;Q9BQ39 A0A087WVC1 DDX50 ATP-dependent RNA helicase DDX50 1 SGWS(0.5)S(0.5)GR 75.043 0.033296 16394000.0 39412.0 42120.0 56042.0 27716.0 39441.0 39325.0 38060.0 36217.0 38798.0 27158.0 True False 38849.97765272435 42022.47372784507 51434.443088375956 29754.327097865604 37121.15792398948 37643.16142105236 40030.560570989735 37899.7740366588 34428.16067894768 31852.224114239674 1.2196943457821616 1.3192948026840845 1.6147834105368475 0.9341365611126604 1.1654180816652708 1.181806372014814 1.256758725149554 1.1898627204407852 1.0808714818616518 1.0 14.959106493210156 -1.5228811780625815 0.06746972299485698 0.7439711855489389 2.25170923686032 0.2372203449498933 0.15531573336249424 414.6795768768906 2.080416846093984 8.440125513991605 59.826144660998565 0.0299998319498268 1.5228811780625815 1.5077380513113812 SGYHDDS(ph)DEDLLE ddPTM_PC-9_Lapatinib_30min_R1 1 SGYHDDSDEDLLE 13 0 Q99523-2;Q99523 Q99523-2 SORT1 Sortilin 1 S(0.036)GYHDDS(0.964)DEDLLE 69.03 0.031456 3916400.0 35053.0 22205.0 30812.0 25702.0 29447.0 32343.0 18457.0 23600.0 37591.0 15366.0 True False 34553.13779206708 22153.585686771126 28278.756297759526 27592.210819358563 27714.98535502949 30959.765285215428 19412.613149205423 24696.542156035764 33357.105729221155 18021.992626092007 1.9172762140653357 1.2292528438113692 1.5691248401033029 1.5310299694280707 1.5378424533868742 1.717888023125272 1.0771624177173447 1.3703558018484832 1.850911074113257 1.0 14.137470913056617 -11.509617825308023 2.981101619770899 0.5318723485910906 1.5127996253894325 0.29101057865284163 0.24790779142438546 12805263.804780776 44970486.74520355 40587254.26019151 0.05986683925509786 3.0930160577001195e-12 11.509617825308023 0.9809272767983419 SGYIDEHELDALLK ddPTM_PC-9_Lapatinib_30min_R1 1 SGYIDEHELDALLK 14 0 P22676;H3BMN5 P22676 CALB2 Calretinin 0 139.19 8.6391e-06 0.0 11345.0 17708.0 16864.0 13009.0 19459.0 17043.0 19191.0 18922.0 16305.0 16635.0 False True 11183.218219581806 17666.99821397627 15477.507016922516 13965.725256751834 18314.45987786596 16314.110619173438 20184.61607771583 19801.185198157153 14468.559200738237 19510.337585255806 0.5731945011568174 0.9055198628304325 0.7932977555764619 0.7158115637786759 0.9387054323297007 0.8361777723160569 1.034560062813551 1.0149073593232514 0.7415842569362971 1.0 14.251951120508222 -6.269207663800391 24.572985302807773 0.9291725013059771 0.7615920465114949 0.37949349076745686 0.11256631199915175 541.1937312980475 1711925.1989195643 0.034083504831025506 0.03937957071036598 5.380124630401486e-07 6.269207663800391 -0.16758045479448214 SGYIS(ph)ESENSEISQQVR ddPTM_PC-9_AZD4547_30min_R2 1 SGYISESENSEISQQVR 17 0 A0A075B754;Q96QE3;Q96QE3-2 A0A075B754 ATAD5 ATPase family AAA domain-containing protein 5 1 SGYIS(0.974)ES(0.026)ENSEISQQVR 110.34 0.0032196 0.0 2206.2 4001.3 4367.8 6212.6 5163.3 3952.9 3261.2 4727.1 2116.5 4140.3 True False 2907.7257081892667 5294.641975313811 4309.880118130179 4780.381053713186 4446.464920045531 3705.724538113796 3551.4404822184747 3996.635312951623 2228.3738690796126 3995.349357209238 0.7277775854425709 1.3252012532421276 1.0787242197865374 1.1964863711073053 1.1129101669225236 0.9275095133863974 0.8888936022103372 1.0003218631532345 0.5577419318935698 1.0 11.964105943979746 -6.873665509942942 3.1566089423518857 0.8648590888309216 1.107931863732852 0.25661771077018325 0.18233038892077866 0.33077556167574984 6.5624558643120645 0.06572031083224873 0.05750675849948953 1.337625348011758e-07 6.873665509942942 0.24307277490193036 SGYIS(ph)ESENSEISQQVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGYISESENSEISQQVR 17 0 A0A075B754;Q96QE3;Q96QE3-2 A0A075B754 ATAD5 ATPase family AAA domain-containing protein 5 1 S(0.001)GYIS(0.975)ES(0.023)ENSEISQQVR 96.15299999999999 0.011840999999999999 0.0 12420.0 11569.0 7955.7 10334.0 16558.0 11154.0 11251.0 12571.0 13169.0 8815.8 True False 14522.460693818342 12717.4938631426 8145.394060160262 9755.019483280044 13313.57876259754 10569.064604505209 10185.223829813931 12241.024570075497 13361.571711699677 10414.0347541656 1.3945085681617664 1.2211879606082185 0.7821554519877241 0.9367185450747656 1.2784265730697824 1.014886626941359 0.9780285998891886 1.1754353484540758 1.2830350605806329 1.0 13.34624150602235 -10.48030092194185 10.411273688401463 0.9999967024246244 1.1052937444214015 0.033370220558671226 0.17910033440651335 0.0 0.0 0.18180038900018702 0.044093070978008846 3.309017607368101e-11 10.48030092194185 0.10529704199677714 SGYIS(ph)ESENSEISQQVR ddPTM_PC-9_Lapatinib_30min_R1 1 SGYISESENSEISQQVR 17 0 A0A075B754;Q96QE3;Q96QE3-2 A0A075B754 ATAD5 ATPase family AAA domain-containing protein 5 1 SGYIS(0.971)ES(0.028)ENSEISQQVR 144.17 1.6465000000000002e-08 0.0 13752.0 12102.0 10314.0 7615.3 11607.0 11197.0 9865.9 10483.0 13035.0 8321.3 True False 13555.893958192071 12073.97856254467 9466.022733191352 8175.354565896093 10924.299080239998 10718.130411481847 10376.708027780554 10970.078450073006 11566.861035364784 9759.625617564716 1.3889768408529 1.2371354225734579 0.9699165832913758 0.8376709195875958 1.1193358749929077 1.0982112256634187 1.0632280821413125 1.1240265641265788 1.1851746663875637 1.0 13.252610091257397 -5.0242042988223385 3.7414627008475376 1.052045691188471 1.371865700593637 0.5838161045677399 0.09294189203822818 0.16342474111489397 4.861203084706837 0.0262740095250592 0.10264528708926424 9.457921414917416e-06 5.0242042988223385 0.319820009405166 SGYISES(ph)ENSEISQQVR ddPTM_PC-9_AZD4547_30min_R2 1 SGYISESENSEISQQVR 17 0 A0A075B754;Q96QE3;Q96QE3-2 A0A075B754 ATAD5 ATPase family AAA domain-containing protein 5 1 SGYIS(0.41)ES(0.54)ENS(0.049)EISQQVR 87.419 0.0028986999999999997 2632900.0 2575.1 5081.8 6500.9 8190.5 5924.4 5455.6 4470.4 6365.5 5215.4 5303.5 True False 3393.928234592593 6724.392469984687 6414.693818387396 6302.306766963563 5101.8993225878285 5114.460469562508 4868.25693968768 5381.8582396381635 5491.075396549875 5117.826079259767 0.6631581812337564 1.3139157849141467 1.2534020732715494 1.231442153242362 0.9968879839945163 0.9993423751325005 0.9512353222428801 1.0515906864143743 1.0729312234354191 1.0 12.321315405299929 -6.286891849777671 23.970319596467714 1.010906536587754 1.1395051842537118 0.07503426662892587 0.1697829677635914 1029.4208899863897 969472.0197688641 0.052438071898114655 0.05948599033288347 5.165449859184926e-07 6.286891849777671 0.12859864766595774 SGYLLPDTK ddPTM_PC-9_Lapatinib_30min_R1 2 SGYLLPDTK 9 0 P14625;H0YIV0 P14625 HSP90B1 Endoplasmin 0 ; 105.4 0.012159 14759300.0 192758.0 146813.0 161608.0 145473.0 163931.0 146295.0 155782.0 130410.0 142511.0 149272.0 False True 190009.2355725119 146473.06351866398 148321.2140649204 156171.5697037022 154288.9008807465 140038.30388030136 163847.62971281997 136469.32468511097 126459.91047264062 175073.46630756257 1.08531143856323 0.8366377076315239 0.847194136228246 0.8920344869927107 0.8812808938717047 0.7998830824214519 0.9358792806728263 0.7794974736226832 0.7223248224861244 1.0 17.417600923558588 -4.759365337047436 24.987800532092265 0.8506238950149533 1.085311740068781 0.4569884574698968 0.07519177028146358 48.02564803307921 578463.0906059096 0.01808236639756193 0.11551819238817732 1.740342247364231e-05 4.759365337047436 0.23468784505382778 SGYLSSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SGYLSSER 8 0 P15311;E7EQR4 P15311 EZR Ezrin 0 96.19 0.028547000000000003 4716300.0 12331.0 14544.0 17159.0 16133.0 19439.0 16073.0 15945.0 11962.0 10784.0 7356.4 False True 14418.394751648468 15987.832202052552 17568.135635869887 15229.12031389171 15630.067494029094 15230.10358510061 14434.574168196881 11648.010174786652 10941.69559867639 8690.05708676964 1.6591829728713814 1.8397844850056926 2.021636389778942 1.7524764408139049 1.7986150537290966 1.7525895898069532 1.661044803741635 1.3403836198637187 1.2591051461945864 1.0 13.085149939092895 -7.970077201444458 0.9551631260291864 1.0161144592376183 1.8342106837180792 0.9046225189198361 0.0911643921908349 0.15006329746636043 0.2560854493486847 0.08517775918565919 0.03243682420048024 1.0713288457924924e-08 7.970077201444458 0.8180962244804608 SGYLSSER ddPTM_PC-9_Lapatinib_30min_R1 1 SGYLSSER 8 0 P15311;E7EQR4 P15311 EZR Ezrin 0 91.626 0.039549 7340500.0 44924.0 42378.0 41896.0 47681.0 45266.0 36821.0 38949.0 41428.0 49063.0 42901.0 False True 44283.37552194735 42279.87634469656 38451.47260323684 51187.61979915321 42603.5428763801 35246.251663943294 40965.58864107937 43352.896120349564 43537.00828370558 50316.380688010795 0.8800985865125834 0.8402805560848071 0.7641939280501334 1.0173152182098426 0.8467131835365003 0.7004925867480298 0.8141600822819217 0.8616060123473772 0.8652651023065223 1.0 15.618740530875353 -8.873603002027812 1.6765714869526898 0.9998447898338045 0.8383396692618477 0.2765416282326053 0.07705030515567104 2.173894649026356 8.578103151355995 0.07729220109694518 0.021938854479977475 1.3378178860076198e-09 8.873603002027812 -0.16150512057195687 SGYSSPGS(ph)PGTPGSR ddPTM_PC-9_AZD4547_30min_R2 2 SGYSSPGSPGTPGSR 15 0 I3L170;A0A0G2JQJ7;A0A0G2JPD5;A0A0G2JS76;A0A0G2JMX7;P10636-3;P10636-2;P10636-4;P10636-6;P10636-5;P10636-7;P10636-8;P10636;P10636-9 I3L170 MAPT Microtubule-associated protein;Microtubule-associated protein tau 1 SGYS(0.003)S(0.051)PGS(0.927)PGT(0.019)PGSR;SGYS(0.001)S(0.003)PGS(0.992)PGT(0.004)PGSR 114.21 0.00017931 7122100.0 18147.2 17958.699999999997 20346.7 31114.0 29860.0 25810.0 21710.0 29172.0 20561.0 23332.0 True False 23917.632114791162 23763.498573480658 20076.88946370239 23941.14800650806 25714.454421118167 24196.096619878364 23642.147942157197 24664.13770587139 21647.812483886573 22515.153781708097 1.0622904176751604 1.0554446486964149 0.8917056333860524 1.0633348649814012 1.1420954380515609 1.0746582881230822 1.0500549172959546 1.0954461135375049 0.9614774428711131 1.0 14.45860871107553 -5.018854503089007 24.906836920375977 1.0403019433131118 1.0605790873064884 0.01539465607355539 0.0671789624605491 4400.047869222868 5812529.838628732 0.017988760918288712 0.04942823754671798 9.575148032356102e-06 5.018854503089007 0.020277143993376656 SGYSSPGS(ph)PGTPGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SGYSSPGSPGTPGSR 15 0 I3L170;A0A0G2JQJ7;A0A0G2JPD5;A0A0G2JS76;A0A0G2JMX7;P10636-3;P10636-2;P10636-4;P10636-6;P10636-5;P10636-7;P10636-8;P10636;P10636-9 I3L170 MAPT Microtubule-associated protein;Microtubule-associated protein tau 1 S(0.001)GYS(0.028)S(0.453)PGS(0.498)PGT(0.02)PGS(0.001)R;SGYS(0.002)S(0.002)PGS(0.495)PGT(0.495)PGS(0.006)R 103.66 0.001243 2601100.0 16698.5 16239.5 19973.2 21604.1 28240.0 24604.0 22975.6 20939.6 23020.0 18307.4 True False 19525.226239591437 17851.65023688341 20449.436836782814 20393.69231843723 22706.574722536217 23313.722927133418 20799.184839060785 20389.95768734012 23356.62395043867 21626.386698701335 0.9028427407507666 0.8254569052885475 0.9455780626548587 0.9430004467487799 1.049947688390301 1.078022105677663 0.961750343635064 0.9428277581184904 1.0800058408204285 1.0 14.40050502185714 -5.720721471132032 1.811040116510096 1.0141881167551723 0.8666224690814263 0.5862225093311044 0.04920364157061432 0.25326324967904235 1.685767891430904 0.01565145969454376 0.03380963790430745 1.902297901712384e-06 5.720721471132032 -0.14756564767374603 SGYSSPGS(ph)PGTPGSR ddPTM_PC-9_Lapatinib_30min_R1 2 SGYSSPGSPGTPGSR 15 0 I3L170;A0A0G2JQJ7;A0A0G2JPD5;A0A0G2JS76;A0A0G2JMX7;P10636-3;P10636-2;P10636-4;P10636-6;P10636-5;P10636-7;P10636-8;P10636;P10636-9 I3L170 MAPT Microtubule-associated protein;Microtubule-associated protein tau 1 SGYS(0.003)S(0.021)PGS(0.932)PGT(0.038)PGS(0.007)R;SGYS(0.029)S(0.469)PGS(0.502)PGTPGSR 130.95 1.0872e-05 6131100.0 32468.0 30353.7 36255.0 32645.0 34446.0 29186.1 31534.0 26602.2 30666.0 29305.0 True False 32005.000366098033 30283.41787257576 33274.25384834714 35045.822200527604 32419.954003441635 27937.878539122095 33166.67622295298 27838.23532810569 27212.072152704004 34370.330203542006 0.9311810557700079 0.8810918514089494 0.9681098101559145 1.0196533461559816 0.9432540744138858 0.8128487091533086 0.964979854035124 0.8099496037206195 0.7917314728009126 1.0 15.068876091624052 -6.644643767982375 8.750284319674778 0.8697286925271422 0.950660175869456 0.209795321426687 0.07016248537883857 0.39694151992829574 28.70556576170472 0.023224447480765784 0.02320608542501508 2.2665026544074765e-07 6.644643767982375 0.0809314833423137 SHALNTS(ph)Q ddPTM_PC-9_AZD4547_30min_R2 1 SHALNTSQ 8 0 Q86YJ6-4;Q86YJ6 Q86YJ6-4 THNSL2 Threonine synthase-like 2 1 SHALNT(0.122)S(0.878)Q 73.84100000000001 0.028852 1810400.0 20414.0 21252.0 29898.0 41081.0 46478.0 38043.0 20941.0 35791.0 25497.0 42818.0 True False 26905.227362422134 28121.293394489065 29501.532984993843 31610.410145123016 40025.331968678205 35664.1651960493 22804.708431907595 30260.323345360055 26844.719366842826 41318.95485278489 0.651159436589881 0.6805906271027979 0.713995140731529 0.7650341170958365 0.9686917810792716 0.8631429648479007 0.551918810946656 0.7323593603268626 0.6496950240510136 1.0 15.33451614179274 -5.563737039978865 2.7252811918091955 0.7792824334013279 0.6676679339548283 0.13495157203295882 0.12761386083489015 0.6618621549439058 9.879871916889316 0.03818116778831172 0.08125991910977506 2.7306306459732216e-06 5.563737039978865 -0.1116144994464996 SHEAEVLK ddPTM_PC-9_AZD4547_30min_R2 4 SHEAEVLK 8 0 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 0 ;;; 112.84 0.0031250999999999996 20488700.0 218087.0 211269.0 249863.0 384394.0 320502.0 278747.0 231374.0 290865.0 264883.0 268516.0 False True 287434.12950860016 279557.57265952893 246549.6533624158 295777.9021280985 276005.8295672206 261316.90602484488 251965.83776916962 245918.49766276835 278884.1746106381 259115.33656990933 1.1092903002715566 1.0788924204959374 0.9515054439701089 1.141491298984912 1.0651852307196576 1.0084964845542501 0.9724080446360968 0.9490696340794151 1.0762935853293083 1.0 17.983234883002062 -6.806746446263936 4.506621505006289 0.9949301845267018 1.067555349922534 0.27669411905699126 0.05485534554327048 0.2809879511745611 12.261932229760177 0.019708468898540558 0.017795810570498657 1.5604632807311085e-07 6.806746446263936 0.0726251653958323 SHEAEVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SHEAEVLK 8 0 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 0 ;; 124.08 0.0027843000000000004 11409900.0 133155.0 131245.0 141419.0 157973.0 172027.0 149206.0 152126.0 147308.0 124061.0 123220.0 False True 155695.51156887156 144274.136232012 144790.96529454444 149122.28496537625 138319.54425615244 141381.3746978486 137715.52398313725 143441.3210857275 125875.1574246467 145558.81059101675 1.0696398997538965 0.9911741903235638 0.9947248449382445 1.0244813375424726 0.950265694632496 0.9713007005470409 0.9461160298299143 0.9854526874966102 0.8647718191262492 1.0 17.15124264204084 -3.1171927639991703 0.3692502718437494 0.9457091975056161 1.4006523469402452 0.4281964134769508 0.03868371787091934 19.649208781288753 0.8006795074872033 0.030490772425910556 5.107670212432335 0.0007634968260853249 3.1171927639991703 0.4549431494346291 SHEAEVLK ddPTM_PC-9_Lapatinib_30min_R1 4 SHEAEVLK 8 0 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 0 ;;; 125.31 0.002875 20349400.0 316785.0 277041.0 308883.0 275177.0 306472.0 300996.0 283934.0 257631.0 287855.0 260014.0 False True 312267.58780874574 276399.5285858484 283487.83206285984 295414.4345435618 288445.9195071347 288123.10273594613 298634.7132202679 269601.47678820597 255433.73865246857 304957.073453123 1.02397227345096 0.9063555255698492 0.9295991362090399 0.9687082552258685 0.945857448856564 0.9447988842279977 0.9792680321814967 0.8840636937370407 0.8376055546445065 1.0 18.218246653916253 -7.770146384692861 24.996870933011433 0.895625953398866 0.9534999206510136 0.16867499105939843 0.04814934777383747 281.61745174407366 808479.0540682026 0.024414115868082707 0.012015323336237784 1.6976713334613833e-08 7.770146384692861 0.05787396725214766 SHEGETAYIR ddPTM_PC-9_AZD4547_30min_R2 2 SHEGETAYIR 10 0 J3KTL2;Q07955;J3KSR8 J3KTL2 SRSF1 Serine/arginine-rich splicing factor 1 0 ; 194.94 0.00016068 22040000.0 15690.099999999999 14929.0 21082.0 25962.0 24885.0 20400.0 17717.6 22605.0 20635.2 17330.0 False True 20679.2254256461 19754.50729749329 20802.43890526591 19976.86200890153 21430.14729636724 19124.38477510726 19294.43207646083 19111.91666122389 21725.93454440425 16723.281974841466 1.2365530555997297 1.1812578013820494 1.2439208366253187 1.194553918241333 1.281455836755416 1.143578443745553 1.1537467409499766 1.1428328894995547 1.2991429898203464 1.0 14.029570386309297 -6.78877724825759 24.915415771168988 1.157155151063772 1.224053192515326 0.22894072958901102 0.07197711937162922 371.44641573028184 338529.3034330784 0.02403187186880894 0.02119902713152058 1.6263827214316565e-07 6.78877724825759 0.06689804145155387 SHEGETAYIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SHEGETAYIR 10 0 J3KTL2;Q07955;J3KSR8 J3KTL2 SRSF1 Serine/arginine-rich splicing factor 1 0 ; 143.4 9.7646e-05 16797000.0 14132.5 21914.4 30329.0 22305.9 28362.0 24534.0 19779.0 21339.5 20093.3 19279.0 False True 16524.853120401578 24089.91680477586 31052.15838337301 21056.172739703525 22804.66969832055 23247.39385036139 17905.389932440637 20779.360736069193 20387.12649971108 22774.130087519978 0.7255975555113322 1.0577754984361367 1.3634838417116675 0.9245654020059418 1.0013409781485927 1.0207807613736586 0.7862161963434394 0.9124107334161624 0.895187935669299 1.0 14.475108327434521 -7.139384107540458 8.710998263498308 0.8913282972555328 1.0292724709816299 0.11663691271070153 0.1548556814179018 0.645753248108841 43.163179398115204 0.06100848616192262 0.047246606938891135 7.25464043975587e-08 7.139384107540458 0.13794417372609713 SHEGETAYIR ddPTM_PC-9_Lapatinib_30min_R1 3 SHEGETAYIR 10 0 J3KTL2;Q07955;J3KSR8 J3KTL2 SRSF1 Serine/arginine-rich splicing factor 1 0 ;; 134.84 2.3864e-05 24683000.0 8397.2 6244.4 6293.6 9047.3 6653.8 3501.48 4457.9 11603.7 5416.6 6084.9 False True 8277.45438814212 6229.9414754547915 5776.164501998554 9712.668622908057 6262.436565874121 3351.7298627485457 4688.708249327778 12142.850263389499 4806.525468673334 7136.666857380399 1.1598487856529232 0.8729483384827028 0.809364457866647 1.3609530635248415 0.8775015971773726 0.4696491975497423 0.6569885274214446 1.7014736019002967 0.6734972452444877 1.0 12.801034713104974 -10.328854455020188 8.7894154738508 0.9999999958464585 0.9557515655407183 0.0015761628871928668 0.34663760160003265 0.0 0.0 0.33796950524306674 0.08196964519734742 4.689705217633953e-11 10.328854455020188 -0.044248430305740216 SHESNAPGS(ph)AGGQASEKPR ddPTM_PC-9_AZD4547_30min_R2 2 SHESNAPGSAGGQASEKPR 19 1 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 SHESNAPGS(0.994)AGGQAS(0.006)EKPR;SHESNAPGS(0.998)AGGQAS(0.002)EKPR 98.29899999999999 0.00026421 6930900.0 1434.92 938.4 8593.3 25750.0 17179.2 13098.2 4472.7 17171.4 7584.400000000001 11338.3 True False 1891.1947118098747 1241.7194485878285 8479.34722723753 19813.735333534187 14794.16461457714 12279.167483397543 4870.761635231989 14517.954689517352 7985.295900140522 10941.349568109921 0.17284839498429186 0.11348869176129715 0.7749818406270248 1.810904149455572 1.3521334386113375 1.1222717459998608 0.44517009578311056 1.3268888448488971 0.7298273261842189 1.0 13.417503078844145 -5.394959238218237 4.044753424487922 1.1190809745072883 0.14883810353078133 0.5439230909762602 0.349110991193219 0.17378477648994226 4.774736738820506 0.0981836027573048 0.2187057723507201 4.027548341017179e-06 5.394959238218237 -0.970242870976507 SHESNAPGS(ph)AGGQASEKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SHESNAPGSAGGQASEKPR 19 1 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 SHESNAPGS(1)AGGQASEKPR;SHESNAPGS(0.999)AGGQAS(0.001)EKPR 156.2 7.689099999999999e-06 4023800.0 3650.2 4891.200000000001 16134.4 13598.3 16977.7 20700.7 12692.3 11300.2 16657.0 9064.0 True False 4268.106765263747 5376.76601118533 16519.105286052745 12836.43133728342 13651.041560439213 19615.118850500363 11489.993459705573 11003.581723551599 16900.577113051975 10707.231449415474 0.39861908145235336 0.5021621169381612 1.5427989358495235 1.1988562494354396 1.274936628103285 1.8319505787437877 1.0731059204228588 1.0276775817853738 1.5784264301090274 1.0 13.386297872659313 -5.248684254227973 22.139284483013068 1.3210636822127149 0.4503895126097257 0.6485594515863222 0.25484718168141074 98.41400602110436 170814.10798805935 0.06427342662583908 0.1667787721478736 5.640475871591893e-06 5.248684254227973 -0.8706741696029892 SHESNAPGS(ph)AGGQASEKPR ddPTM_PC-9_Lapatinib_30min_R1 1 SHESNAPGSAGGQASEKPR 19 1 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 SHESNAPGS(1)AGGQASEKPR 96.777 0.00030201 1156700.0 2907.3 1326.1 8886.2 2764.9 4823.3 7405.7 1895.9 3371.5 9185.0 3019.3 True False 2865.8413688664778 1323.0294969253412 8155.610937723963 2968.239969436018 4539.602976972653 7088.975474529882 1994.0604252900557 3528.1521982658696 8150.488577662108 3541.1819820356377 0.8092894924363807 0.3736123993731612 2.3030759162046044 0.8382059957646498 1.2819456893212464 2.001867034931316 0.5631058882050948 0.9963204986821158 2.3016294048172083 1.0 11.790015270676745 -5.2097467370781265 24.997894124542213 1.3764266238295462 0.5914503172213655 0.23596971425886637 0.5871150163783277 507.4652788650847 245401.73181400902 0.1445346944659832 0.3824021143277497 6.169546799150232e-06 5.2097467370781265 -0.7849763066081806 SHGLEPAAPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 SHGLEPAAPSPR 12 0 Q9ULL5;Q9ULL5-2;A0A3Q5ADB5 Q9ULL5 PRR12 Proline-rich protein 12 1 SHGLEPAAPS(1)PR 86.288 0.0092037 4728800.0 22254.0 19660.0 27262.0 33095.0 23376.0 26876.0 19769.0 25454.0 25517.0 24553.0 True False 29330.309088044592 26014.710527745854 26900.488067325645 25465.45906265298 20130.64589913122 25195.439471361897 21528.402702372456 21520.669174730938 26865.77652601204 23693.406943351576 1.237910156110949 1.097972553712696 1.135357533496211 1.0747909375607396 0.8496306988379283 1.0633945355178984 0.9086241904275136 0.9082977904437541 1.1338925039461512 1.0 14.532198042326707 -6.0059714548805845 4.895947398153239 0.9721671836721804 1.1465182992413516 0.4838974996966495 0.08335689418257043 0.156498810429474 10.659885583304241 0.02360713881567552 0.033371339708969223 9.863443135121006e-07 6.0059714548805845 0.17435111556917127 SHGLEPAAPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHGLEPAAPSPR 12 0 Q9ULL5;Q9ULL5-2;A0A3Q5ADB5 Q9ULL5 PRR12 Proline-rich protein 12 1 SHGLEPAAPS(1)PR 104.81 0.0036387 0.0 19591.0 16165.0 18898.0 13394.0 24683.0 17024.0 16288.0 16600.0 17356.0 11406.0 True False 22907.36936011233 17769.75436923675 19348.599991064108 12643.577603933889 19846.543338398078 16131.231470960785 14745.08272509193 16164.267589153853 17609.798665673905 13473.817510153678 1.7001394996517996 1.3188359094106563 1.4360146986170235 0.9383812415750672 1.472971065805367 1.1972279911617119 1.0943507817276168 1.1996798663016395 1.306964314486478 1.0 13.717871044208506 -1.5228791460297944 0.7754844496985658 1.190461352616897 106.61667396063866 0.4851324059676315 0.15742963148809197 370.1568422694374 1.434149727961321 0.05476881293431813 68380.514695435 0.029999972317221017 1.5228791460297944 105.42621260802177 SHGRS(ph)LMTNFGK ddPTM_PC-9_Lapatinib_30min_R1 1 SHGRSLMTNFGK 12 1 A0A2U3TZV8;Q4KWH8-2;Q4KWH8;Q4KWH8-3;Q4KWH8-4 A0A2U3TZV8 PLCH1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 1 SHGRS(1)LMTNFGK 76.92699999999999 0.027598 1782700.0 8036.8 21167.0 17840.0 21190.0 26585.0 21670.0 25594.0 23710.0 20506.0 28954.0 True False 7922.193758231383 21117.989111996605 16373.264064391467 22748.383287767796 25021.322568121002 20743.22461523725 26919.13208759622 24811.653157610508 18196.398342247045 33958.66032122012 0.23328934897001677 0.6218734458968151 0.48215282668733916 0.6698845912231927 0.7368171279856306 0.6108375424420145 0.7927030051528553 0.7306428735089463 0.5358396995088897 1.0 15.051491924834531 -4.784052453208434 0.18183309510886628 0.9365240503404922 2.857772532413712e-45 0.5610606464486856 0.12808150916011335 14.615248092912372 0.4844118700720812 0.36269348888243996 3.2031424454802164 1.64417313131971e-05 4.784052453208434 -0.9365240503404922 SHGS(ph)PTHVR ddPTM_PC-9_AZD4547_30min_R2 2 SHGSPTHVR 9 0 Q5VT52-5 Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 S(0.15)HGS(0.748)PT(0.101)HVR;S(0.001)HGS(0.872)PT(0.127)HVR 87.713 0.006051300000000001 7586300.0 17773.9 11123.2 16096.1 12649.599999999999 11002.6 13226.8 10090.0 11909.599999999999 22952.0 31397.0 True False 23425.630479913532 14718.556873968615 15882.655196995089 9733.430154371805 9475.07890870043 12399.726105068064 10987.990453079972 10069.244975382084 24165.195862563305 30297.800586503028 0.7731792416096736 0.48579621586543126 0.5242180913973817 0.3212586381173762 0.31273157540423446 0.4092615920969477 0.3626662741312935 0.33234244006040825 0.7975891119082863 1.0 14.886925447237305 -8.442820564133818 3.8208359449433362 0.9955720969875946 0.43374681761139317 0.6731521407244476 0.13112108786095694 0.12356692986515237 3.323863919811676 0.13240476860272699 0.034862901823817335 3.6072765276447687e-09 8.442820564133818 -0.5618252793762015 SHGS(ph)PTHVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SHGSPTHVR 9 0 Q5VT52-5 Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 S(0.48)HGS(0.518)PT(0.002)HVR;SHGS(0.981)PT(0.019)HVR;SHGS(0.84)PT(0.159)HVR;SHGS(0.891)PT(0.109)HVR 102.05 0.0018716999999999998 9588860.0 8640.72 14233.2 16377.240000000002 13526.8 30581.0 25391.23 8002.299999999999 16809.83 27905.6 33734.5 True False 10103.423234000804 15646.178032058186 16767.73551262858 12768.9372504773 24588.87257754532 24059.66920009421 7244.264212365124 16368.58977398712 28313.666607791518 39850.29780784495 0.253534447414138 0.3926238671415417 0.4207681356230084 0.3204226305170447 0.6170310870977918 0.6037513023392715 0.18178695294314748 0.41075200624384767 0.7105007532018411 1.0 15.282302885303356 -14.522878745278422 0.1845411495563621 3.4358258983884182 0.31890748497999705 0.6200536146276054 0.14297342440926716 96.68730244193067 0.9352858645588026 85.98400938978317 0.4402184663053676 3.000000000013229e-15 14.522878745278422 -3.1169184134084214 SHGS(ph)PTHVR ddPTM_PC-9_Lapatinib_30min_R1 2 SHGSPTHVR 9 0 Q5VT52-5 Q5VT52-5 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 S(0.002)HGS(0.893)PT(0.105)HVR;SHGS(0.884)PT(0.116)HVR 98.182 0.0025754000000000003 11059200.0 9619.5 9273.6 6419.0 8890.3 11443.8 7541.5 15795.5 16464.9 9280.0 11740.0 True False 9482.324165999747 9252.127548968281 5891.254598056547 9544.122319171407 10770.69818337646 7218.967625095144 16613.31370202492 17229.919362072604 8234.788677267758 13769.243357433303 0.6886597846991157 0.6719416099195847 0.4278560880308767 0.6931479146251729 0.7822287618703403 0.5242820856382059 1.2065524060228225 1.2513337817339876 0.598056731477712 1.0 13.749161662735407 -7.256000482954389 24.98949847396868 1.034930215690692 0.6336146805222443 0.4977298741220961 0.18782512831966222 367.61568204743577 1689048.1906020918 0.07285922065110957 0.054793953682280704 5.546250961902925e-08 7.256000482954389 -0.40131553516844776 SHHAPMS(ph)PGSSGGGGQPLAR ddPTM_PC-9_AZD4547_30min_R2 7 SHHAPMSPGSSGGGGQPLAR 20 0 O14497-2;O14497 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 S(0.001)HHAPMS(0.997)PGS(0.002)SGGGGQPLAR;SHHAPMS(0.988)PGS(0.009)S(0.003)GGGGQPLAR;SHHAPMS(0.994)PGS(0.004)S(0.002)GGGGQPLAR;SHHAPMS(0.997)PGS(0.002)S(0.001)GGGGQPLAR;S(0.002)HHAPMS(0.969)PGS(0.025)S(0.003)GGGGQPLAR;SHHAPMS(1)PGSSGGGGQPLAR;S(0.002)HHAPMS(0.993)PGS(0.003)S(0.001)GGGGQPLAR 85.06200000000001 0.00054145 57934900.0 18164.4 22249.149999999998 75988.0 176527.0 109629.5 84548.3 48105.899999999994 122142.0 57151.100000000006 80676.6 True False 23940.301357008946 29440.752631658033 74980.34947032278 135831.42746496256 94409.3362679159 79261.48143535313 52387.23190652327 103267.76044393747 60171.990469716875 77852.13679004576 0.3075098814766247 0.3781624223244487 0.9631122864685434 1.744736022227332 1.2126749522947862 1.0181028383216781 0.6729067957094474 1.326460193667303 0.7729009498093894 1.0 16.248449016722695 -5.2955412602224845 4.182531649482298 1.118059168646684 0.3275288130078923 0.5322138946153483 0.2817091071406042 0.15538409126764338 6.2501944949389205 0.07795869847874679 0.18774128129142725 5.06359240491226e-06 5.2955412602224845 -0.7905303556387917 SHHAPMS(ph)PGSSGGGGQPLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 SHHAPMSPGSSGGGGQPLAR 20 0 O14497-2;O14497 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 SHHAPMS(0.999)PGS(0.001)SGGGGQPLAR;S(0.004)HHAPMS(0.996)PGSSGGGGQPLAR;S(0.008)HHAPMS(0.98)PGS(0.008)S(0.004)GGGGQPLAR;S(0.256)HHAPMS(0.741)PGS(0.002)SGGGGQPLAR;SHHAPMS(0.998)PGS(0.002)SGGGGQPLAR;S(0.007)HHAPMS(0.987)PGS(0.004)S(0.002)GGGGQPLAR;S(0.174)HHAPMS(0.77)PGS(0.042)S(0.014)GGGGQPLAR 104.88 0.00010511 30430700.0 20858.08 31627.98 53413.4 46153.299999999996 65078.799999999996 59338.7 47463.6 44740.1 51508.299999999996 33730.399999999994 True False 24388.940978141596 34767.796832362044 54686.978027447556 43567.48023201748 52327.07631207473 56226.87411218875 42967.50420129376 43565.71978105435 52261.51144337009 39845.4545103005 0.6120884120379849 0.8725662000762013 1.3724772047288445 1.0934115513917602 1.3132508326275356 1.4111239237502855 1.07835397360535 1.0933673694145494 1.3116053533749978 1.0 15.28212753338925 -5.0316513651670345 3.682402754567364 1.2137421609602908 0.640503455068307 0.6762749257919388 0.1345379150352113 0.12069800566087568 3.3967331931278735 0.034374215666794335 0.13292205720625475 9.2971242451368e-06 5.0316513651670345 -0.5732387058919838 SHHAPMS(ph)PGSSGGGGQPLAR ddPTM_PC-9_Lapatinib_30min_R1 2 SHHAPMSPGSSGGGGQPLAR 20 0 O14497-2;O14497 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 SHHAPMS(0.989)PGS(0.009)S(0.001)GGGGQPLAR;SHHAPMS(0.96)PGS(0.028)S(0.012)GGGGQPLAR 60.938 0.0088089 14166100.0 3402.46 1880.24 12052.9 3536.6000000000004 9157.8 9022.7 5856.0 7229.5 11363.3 2946.33 True False 3353.9402964652522 1875.886419801601 11061.957087539457 3796.693361751754 8619.156208927528 8636.820153940986 6159.19502637194 7565.408962587311 10083.445493146202 3455.5992147620527 0.9705813921178933 0.542854163118211 3.2011690013944993 1.098707670013517 2.4942580644500554 2.49936975244269 1.7823811858910996 2.189318984177467 2.9180020212038777 1.0 11.754720186074115 -5.238122934015098 24.912508362874657 2.1647734601082975 0.7567174177119839 0.40249949834282894 0.6777521533088611 690.8459081375788 738133.2663092521 0.16013279213935827 0.42310352149761155 5.779324312104673e-06 5.238122934015098 -1.4080560423963138 SHHLDEDEERER ddPTM_PC-9_AZD4547_30min_R2 1 SHHLDEDEERER 12 1 F5GWA4;Q9H3F6-2;Q9H3F6;F5GWK6;F5H268;B3KVY5;Q9H3F6-3 F5GWA4 KCTD10 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 0 56.548 0.034291 3531800.0 1863.7 5635.6 10926.0 20349.0 14636.0 11849.0 7847.1 15019.0 11158.0 9267.5 False True 2456.3178326318284 7457.197489835434 10781.114101078416 15657.852438916012 12604.044035749688 11108.080156874796 8545.476698153008 12698.158652285845 11747.789100491525 8943.047645807465 0.27466227732593596 0.8338541608163518 1.2055302093948526 1.7508407714071024 1.4093678726690575 1.2420911300950417 0.955544131776952 1.4198916471432188 1.3136225552816925 1.0 13.126550846968284 -4.941087239779993 2.117628274533012 1.311534223180394 0.17221978387003112 0.6918010449185037 0.21249104750077083 0.2772769335604496 1.8332538604815805 0.060757508091023135 0.5390356636176583 1.145282857333085e-05 4.941087239779993 -1.139314439310363 SHHLDEDEERER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SHHLDEDEERER 12 1 F5GWA4;Q9H3F6-2;Q9H3F6;F5GWK6;F5H268;B3KVY5;Q9H3F6-3 F5GWA4 KCTD10 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 0 ; 113.67 0.00036317 3934900.0 6881.2 8694.9 19249.9 18088.4 25874.1 20572.7 16276.0 17356.9 21591.8 10578.900000000001 False True 8046.05125010489 9558.072209407776 19708.890621652285 17074.965591384043 20804.255843780975 19493.831395831487 14734.219451964407 16901.299766155695 21907.539227327597 12496.770827473676 0.6438504283375311 0.7648433616462516 1.5771186727952982 1.3663502217585186 1.6647705340041612 1.5599094890157574 1.1790421425966926 1.352453365712591 1.7530560118110436 1.0 13.609267729393224 -5.216472745000009 6.227736041169291 1.445711324042142 0.6914183626513234 0.6456722156039718 0.2154009433441106 0.1225943345968047 12.356094420337417 0.05334517895222404 0.14233876012632393 6.0747338484826356e-06 5.216472745000009 -0.7542929613908186 SHIAS(ph)PSPCPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SHIASPSPCPDR 12 0 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 1 SHIAS(0.936)PS(0.064)PCPDR;S(0.006)HIAS(0.973)PS(0.021)PCPDR 77.279 0.017738 7563400.0 45509.0 35994.0 48103.0 55841.0 66697.0 52372.0 54899.0 50443.0 47906.0 36977.0 True False 53212.77485627851 39567.24644394109 49249.95795164341 52712.40980896463 53628.20163842062 49625.520124363175 49698.56928565951 49118.92469877641 48606.53462075216 43680.63739022906 1.218223405965722 0.905830336001276 1.1275008995784515 1.206768329364074 1.2277339535896228 1.1360988092051956 1.1377711557106676 1.124501097819691 1.112770726913087 1.0 15.414706287845068 -8.977625894391688 1.482056489201425 1.0000220949750673 1.1335954219124675 0.18267827135737846 0.08564961299469767 4.183039557438235 11.586866330000875 0.08569690599634794 0.024824075882811204 1.052868434701942e-09 8.977625894391688 0.1335733269374002 SHIAS(ph)PSPCPDR ddPTM_PC-9_Lapatinib_30min_R1 1 SHIASPSPCPDR 12 0 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 1 S(0.001)HIAS(0.832)PS(0.167)PCPDR 79.46600000000001 0.015353 2438900.0 22324.0 25447.0 33569.0 25678.0 26640.0 30935.0 28435.0 23432.0 35489.0 20232.0 True False 22005.655666279778 25388.079034959013 30809.08640008731 27566.4457792969 25073.087576255162 29611.98216300712 29907.225166476444 24520.736262721606 31491.85510426245 23729.07424255458 0.9273710150401019 1.0699144338901032 1.2983686630654887 1.1617160238750723 1.0566399396774735 1.247919824444833 1.2603620714727364 1.0333625329026659 1.3271421709232327 1.0 14.534368196401232 -4.936265043507233 3.90342948300667 1.176368101883825 0.9349722022845879 0.33177434940538997 0.10805265281927107 0.24484051692000763 7.188378363120415 0.0258804056905634 0.12928458863129638 1.1580703871995527e-05 4.936265043507233 -0.24139589959923713 SHIEIIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SHIEIIR 7 0 P00390-5;P00390-4;P00390-2;P00390-3;P00390 P00390-5 GSR Glutathione reductase, mitochondrial 0 ; 113.7 0.00071062 3631200.0 30680.0 27650.0 32967.0 32735.0 40365.0 35475.0 37214.0 30757.0 34030.0 30516.0 False True 35873.51804237894 30394.909267516003 33753.05830804373 30900.964078301924 32455.76801257702 33614.62854983165 33688.82051397172 29949.661339735238 34527.62437156505 36048.30923547693 0.9951511958034922 0.8431715637193564 0.9363284720944878 0.8572098035569099 0.9003409230809551 0.9324883541763958 0.9345464802220703 0.8308201403870639 0.9578153623245302 1.0 15.13764397425006 -8.518095147567164 24.452178010900653 1.0000000066019124 0.9025903695177222 0.30713953257157367 0.04729361973330266 275.1866457451698 1406659.440628316 0.042274358751573565 0.01091519252475748 3.0332265758279292e-09 8.518095147567164 -0.09740963708419015 SHIEIIR ddPTM_PC-9_Lapatinib_30min_R1 3 SHIEIIR 7 0 P00390-5;P00390-4;P00390-2;P00390-3;P00390 P00390-5 GSR Glutathione reductase, mitochondrial 0 ;; 108.09 0.0082348 14443600.0 122253.0 113315.0 130475.0 116819.0 109414.0 123600.0 106084.0 98168.0 130032.0 99853.0 False True 120509.64980154527 113052.626079553 119747.84914806513 125410.25895676023 102978.48363620054 118313.91612567248 111576.51044700162 102729.24365990348 115386.4268623364 117112.45800424082 1.0290079454841723 0.9653339021836531 1.0225030811301807 1.0708532729474343 0.879312802336294 1.010259012080407 0.9527296442105354 0.8771845917210918 0.9852617631691932 1.0 16.83753502717557 -6.253649456272687 24.99421673959951 0.947720833818486 1.017923681142888 0.3389899013054407 0.04841965332995463 706.5169309666571 2266880.812385536 0.0141956946109259 0.017997545145470147 5.576356667289557e-07 6.253649456272687 0.07020284732440196 SHILEDDENS(ph)VDISMLK ddPTM_PC-9_AZD4547_30min_R2 2 SHILEDDENSVDISMLK 17 0 O75717-2;O75717 O75717-2 WDHD1 WD repeat and HMG-box DNA-binding protein 1 1 SHILEDDENS(0.948)VDIS(0.052)MLK;SHILEDDENS(0.97)VDIS(0.03)MLK 147.49 7.1211e-05 25405000.0 148584.0 145844.0 198180.0 248256.0 171024.0 186774.0 164886.0 202935.0 160443.0 169116.0 True False 195830.6212608082 192985.22086513572 195552.0037114885 191024.4147169656 147280.2696891262 175094.99225420973 179560.53457349335 171576.05873238077 168923.68942912354 163195.30031490437 1.199977088083604 1.1825415345463273 1.1982698235436198 1.1705264449917474 0.9024786216571907 1.072916878833787 1.1002800584760122 1.0513541652321161 1.0351014343131546 1.0 17.316239985729013 -6.070558657716257 11.55487574407766 1.035546616583745 1.191152375600228 0.7125772352511157 0.05001061147402767 0.533878313887481 86.50920133130361 0.015033502741348128 0.01942109151598909 8.50043874782167e-07 6.070558657716257 0.155605759016483 SHILEDDENS(ph)VDISMLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SHILEDDENSVDISMLK 17 0 O75717-2;O75717 O75717-2 WDHD1 WD repeat and HMG-box DNA-binding protein 1 1 SHILEDDENS(0.996)VDIS(0.004)MLK;SHILEDDENS(0.999)VDIS(0.001)MLK;SHILEDDENS(1)VDISMLK;SHILEDDENS(1)VDISMLK;SHILEDDENS(0.863)VDIS(0.137)MLK;SHILEDDENS(1)VDISMLK 136.61 3.5893000000000003e-05 63279800.0 436256.0 466799.0 463515.0 474404.0 463214.0 378702.0 417184.0 409295.0 363777.0 284070.0 True False 510105.5243512404 513139.7197528828 474566.9554904259 447824.6819185192 372450.54190952226 358842.20045323076 377665.3113693984 398551.4399338994 369096.55042653054 335569.64230311743 1.5201182110819969 1.5291601356757047 1.4142130147212582 1.3345208429611242 1.1099053518467281 1.0693523943059529 1.125445403157942 1.1876862197620695 1.0999104325805744 1.0 18.356252681037688 -5.956668595833082 1.6148078626464943 1.1033526561912126 1.5185945192517862 0.9269860252124175 0.04985993566377332 0.09536835475358077 0.5040200985315804 0.017174229884838067 0.03041396485430289 1.104921448699626e-06 5.956668595833082 0.41524186306057365 SHILEDDENS(ph)VDISMLK ddPTM_PC-9_Lapatinib_30min_R1 5 SHILEDDENSVDISMLK 17 0 O75717-2;O75717 O75717-2 WDHD1 WD repeat and HMG-box DNA-binding protein 1 1 SHILEDDENS(1)VDISMLK;SHILEDDENS(0.998)VDIS(0.002)MLK;SHILEDDENS(1)VDISMLK;SHILEDDENS(0.997)VDIS(0.003)MLK;SHILEDDENS(0.999)VDIS(0.001)MLK 135.36 2.6161999999999998e-05 44265600.0 325994.0 302496.0 323726.0 316025.0 234439.0 241155.0 203004.0 218777.0 243143.0 175975.0 True False 321345.26578002254 301795.58909729915 297110.49789849704 339266.53272849566 220649.75894480787 230841.36280976215 213514.55381379937 228942.17810470454 215757.67493070176 206392.04427805133 1.5569653709476623 1.4622442941197877 1.4395443338805727 1.643796561612791 1.0690807376642315 1.1184605667201626 1.0345096128131401 1.1092587357498804 1.0453778666004832 1.0 17.65502783520858 -6.2717607156986785 24.951030029649196 1.0696145484573303 1.5149600210154526 0.9320117432326059 0.061199375214546915 159.05459575422842 384501.41210718587 0.01839575416898169 0.02109009074812052 5.34858970793813e-07 6.2717607156986785 0.4453454725581223 SHILEDDENSVDIS(ph)MLK ddPTM_PC-9_Lapatinib_30min_R1 1 SHILEDDENSVDISMLK 17 0 O75717-2;O75717 O75717-2 WDHD1 WD repeat and HMG-box DNA-binding protein 1 1 SHILEDDENS(0.24)VDIS(0.76)MLK 78.096 0.006388399999999999 5809900.0 41334.0 35970.0 38443.0 31741.0 27086.0 30556.0 26161.0 24602.0 34827.0 20273.0 True False 40744.56958027273 35886.713674990235 35282.36493427137 34075.339024872 25492.854733124896 29249.19110951499 27515.488573243907 25745.098734016603 30904.416515431494 23777.161037925507 1.7136011113893512 1.5092934609707827 1.4838762658836608 1.433112177291498 1.0721572139105586 1.2301380750570423 1.1572234603347145 1.0827658816354129 1.299752164109825 1.0 14.537288849006003 -5.832045710811444 1.0982984638714492 1.139391212116813 1.6458762556872037 0.8006522662942896 0.0978945684107302 0.23736948569751268 0.5637207324192657 0.035906668380990076 0.09140158780086295 1.4721575452312848e-06 5.832045710811444 0.5064850435703907 SHILYDR ddPTM_PC-9_AZD4547_30min_R2 1 SHILYDR 7 0 Q96S55-2;Q96S55;Q96S55-4;Q96S55-3 Q96S55-2 WRNIP1 ATPase WRNIP1 0 77.282 0.025196 1611300.0 7174.3 7553.6 10463.0 13662.0 11349.0 10800.0 10474.0 13114.0 8612.9 8859.1 False True 9455.578165289757 9995.153481301182 10324.253783597245 10512.436975795885 9773.387247999668 10124.674292703845 11406.165709173403 11087.532629740765 9068.160310416157 8548.945605500177 1.1060519743167245 1.1691679819404337 1.207663992733195 1.2296764374114681 1.1432272117524898 1.1843184832279063 1.334219006123394 1.2969473829155405 1.060734355893191 1.0 13.061530779102748 -8.443994904250332 5.298496501911697 1.0010725466450627 1.208889659318889 0.5615331602797118 0.06413528151002156 0.15316850160351753 6.928818804618646 0.06723630648643072 0.01747510005120398 3.597535562623568e-09 8.443994904250332 0.2078171126738262 SHILYDR ddPTM_PC-9_Lapatinib_30min_R1 2 SHILYDR 7 0 Q96S55-2;Q96S55;Q96S55-4;Q96S55-3 Q96S55-2 WRNIP1 ATPase WRNIP1 0 ; 69.19800000000001 0.039589 3148800.0 17467.2 14680.7 16817.2 13018.5 15834.3 16404.699999999997 14812.5 15013.4 17031.2 15158.0 False True 17218.11452490782 14646.707741129523 15434.5547322693 13975.92391844291 14902.957605431562 15703.109222223471 15579.418771880855 15710.977373111331 15112.966909513214 17778.04010323458 0.96850465095841 0.8238651536433798 0.8681808929804978 0.7861341203691006 0.8382789958224969 0.8832868601396848 0.8763293749712207 0.8837294370965468 0.8500918448689698 1.0 14.117808666079581 -11.54594281465399 0.4609553502398976 1.1445703317803837 0.8588314304137679 0.44259092529026844 0.045390086767152595 59.24208580754739 4.2102776605701875 9.081121636197288 0.023707272605165225 2.8448356740358945e-12 11.54594281465399 -0.28573890136661584 SHISDQS(ph)PLSSK ddPTM_PC-9_AZD4547_30min_R2 1 SHISDQSPLSSK 12 0 P42166 P42166 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin 1 S(0.403)HIS(0.075)DQS(0.518)PLS(0.004)SK 186.29 0.000384 22319000.0 7053.5 7064.8 49551.0 121780.0 68201.0 56626.0 24592.0 78910.0 28779.0 57306.0 True False 9296.366278085845 9348.358440306149 48893.92136395174 93705.50248224438 58732.468384952415 53085.1672683933 26780.640358983423 66716.27267140783 30300.19918650704 55299.7343825889 0.1681086967573718 0.16904888503857762 0.884161956831134 1.6945018548180861 1.0620750540791803 0.9599533860529201 0.4842815369365553 1.2064483386092615 0.5479266677282097 1.0 15.7549849304282 -5.289362912372735 4.946834135007237 1.0020618525867422 0.15956676928097394 0.5127554291554582 0.31713689381600974 0.14202132576439006 9.622533341492389 0.0866528901704287 0.20076312897454499 5.136142773085493e-06 5.289362912372735 -0.8424950833057683 SHISDQS(ph)PLSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHISDQSPLSSK 12 0 P42166 P42166 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin 1 SHIS(0.006)DQS(0.973)PLS(0.02)S(0.001)K 115.91 0.00070105 9166200.0 10672.0 9064.4 27890.0 22019.0 33220.0 29769.0 21330.0 23046.0 21911.0 11353.0 True False 12478.558818392055 9964.253727467347 28555.00337341399 20785.346816561178 26710.779471765345 28207.861234670563 19309.467984173065 22441.066919255423 22231.40692346052 13411.209029701444 0.9304574099737113 0.7429795259621845 2.129189345283784 1.5498488443904221 1.9916757253286934 2.1033048677564694 1.4398006877238962 1.6733067741734393 1.6576735829130111 1.0 13.711151682603099 -5.248958266789033 24.99716186399968 1.7282977287498407 0.8367183263084758 0.5275973790222768 0.32276779508693515 535.7685812020553 1073032.3724728005 0.07824124353998806 0.20390485844268438 5.636918207771581e-06 5.248958266789033 -0.8915794024413649 SHISDQSPLS(ph)SK ddPTM_PC-9_Lapatinib_30min_R1 1 SHISDQSPLSSK 12 0 P42166 P42166 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin 1 SHISDQS(0.265)PLS(0.735)SK 159.58 0.00053266 7470000.0 13421.0 9051.3 32874.0 11607.0 24474.0 25680.0 13498.0 16426.0 34563.0 12600.0 True False 13229.614078890028 9030.342270960211 30171.22661730972 12460.617499816935 23034.48743773532 24581.726263003828 14196.860393778754 17189.211926061173 30670.150975474742 14777.89321155534 0.8952300500145272 0.6110710195076439 2.0416460036209902 0.8431930939975634 1.5587125382475944 1.6634120920418165 0.9606822968972156 1.1631706685104708 2.0754075385720547 1.0 13.851152988012634 -5.224990291276353 24.99429798768998 1.3967088792349716 0.7531502685228845 0.2874678705814855 0.41505928875910464 728.18868639378 499340.0093673141 0.10045657098894298 0.2657651693014124 5.956754598017726e-06 5.224990291276353 -0.6435586107120871 SHLDS(ph)PEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHLDSPEAR 9 0 K7ER08;K7EP90;Q9BTD8-4;Q9BTD8-2;Q9BTD8-3;Q9BTD8 K7ER08 RBM42 RNA-binding protein 42 1 SHLDS(1)PEAR 83.869 0.02992 0.0 22773.0 36608.0 25238.0 31860.0 37616.0 23398.0 30718.0 27681.0 26533.0 17388.0 True False 26628.019112747592 40242.200306156454 25839.769635648012 30074.987491513653 30245.414828715406 22170.96769017509 27808.16866093896 26954.403080443848 26920.994929495602 20540.306756667742 1.2963788432275323 1.959182050340759 1.2580031029604741 1.464193687455558 1.4724909022547688 1.0793883437489562 1.3538341462165333 1.3122687698757944 1.3106423019099547 1.0 14.326170107116884 -1.5228787809664182 0.07573723095676937 0.6677546690124065 3.107807119235047 0.3357941479896511 0.2011551517966309 232.82369783129204 1.2977591500629537 6.719583991888132 59.852719109863536 0.029999997534892985 1.5228787809664182 2.44005245022264 SHLEPSGNPLPATPTTSAPSAPPAS(ph)SQGPDTAPRPSPPQEEAR ddPTM_PC-9_AZD4547_30min_R2 2 SHLEPSGNPLPATPTTSAPSAPPASSQGPDTAPRPSPPQEEAR 43 1 Q8N1F8 Q8N1F8 STK11IP Serine/threonine-protein kinase 11-interacting protein 1 SHLEPSGNPLPAT(0.001)PT(0.015)T(0.015)S(0.013)APS(0.057)APPAS(0.297)S(0.297)QGPDT(0.253)APRPS(0.052)PPQEEAR;SHLEPSGNPLPAT(0.001)PT(0.013)T(0.013)S(0.031)APS(0.124)APPAS(0.405)S(0.405)QGPDT(0.005)APRPS(0.002)PPQEEAR 72.444 1.3745e-09 17760100.0 35371.0 39021.0 57271.0 62551.0 54345.0 58921.0 53908.0 71935.0 50356.0 53140.0 True False 46618.24223749552 51633.775152755436 56511.549119793395 48130.83335331638 46800.134812982826 55236.66055559287 58705.70756636623 60819.09865185307 53017.71535618851 51279.58477455714 0.9090994484929139 1.0069070445822728 1.1020282119724212 0.9385963939629434 0.912646524318254 1.0771666892084328 1.1448163596576866 1.1860294680472736 1.0338951765946 1.0 15.646096959639634 -6.923024701121669 6.7965302901577465 1.1073002669345338 0.9812627248684539 0.3801693902557044 0.07177769913105582 0.22325573425481923 16.071815531785976 0.026029612637850072 0.022922523964032902 1.1939201966092105e-07 6.923024701121669 -0.12603754206607987 SHLEPSGNPLPATPTTSAPSAPPAS(ph)SQGPDTAPRPSPPQEEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHLEPSGNPLPATPTTSAPSAPPASSQGPDTAPRPSPPQEEAR 43 1 Q8N1F8 Q8N1F8 STK11IP Serine/threonine-protein kinase 11-interacting protein 1 SHLEPSGNPLPATPTT(0.001)S(0.001)APS(0.019)APPAS(0.608)S(0.235)QGPDT(0.064)APRPS(0.072)PPQEEAR 74.699 4.0137e-12 7939000.0 7871.8 9670.0 12212.0 13833.0 12940.0 10434.0 10855.0 7399.9 9332.8 7092.0 True False 9204.340264863056 10629.973693196374 12503.180394267898 13057.981857191095 10404.499890567233 9886.822671992766 9826.735816605651 7205.660465842143 9469.274544077054 8377.723459758894 1.0986684281326173 1.2688379777938263 1.4924317392815605 1.55865515493715 1.2419244846817452 1.1801323736075318 1.172960156038435 0.8600976745596133 1.1302920882458412 1.0 13.032342547737487 -7.1128015817705625 1.5007470482240173 1.0064078376207768 1.3529951157876319 0.5063820759264107 0.13918014689498168 0.34469548199011163 1.5447456016120371 0.07971245262361247 0.05380679577193087 7.712557559462178e-08 7.1128015817705625 0.3465872781668551 SHLEPSGNPLPATPTTSAPSAPPAS(ph)SQGPDTAPRPSPPQEEAR ddPTM_PC-9_Lapatinib_30min_R1 1 SHLEPSGNPLPATPTTSAPSAPPASSQGPDTAPRPSPPQEEAR 43 1 Q8N1F8 Q8N1F8 STK11IP Serine/threonine-protein kinase 11-interacting protein 1 SHLEPSGNPLPAT(0.002)PT(0.006)T(0.016)S(0.045)APS(0.127)APPAS(0.373)S(0.373)QGPDT(0.044)APRPS(0.012)PPQEEAR 62.242 1.4833e-06 8581300.0 9401.5 12747.0 12312.0 9955.2 12682.0 13721.0 10721.0 11236.0 13764.0 7275.2 True False 9267.432885976052 12717.485104673351 11299.75488569438 10687.338617573672 11936.069693771324 13134.18481521321 11276.080921744124 11758.065579034648 12213.75337865447 8532.708626405349 1.0861068028617575 1.4904393975575094 1.3242869738603427 1.2525141881091073 1.3988605748043386 1.5392749700333277 1.3215124780950713 1.3779991903916768 1.431404014061578 1.0 13.05878806859517 -10.520044533189456 4.337756290106536 0.9999852057921139 1.3638848098017238 0.44129095153822917 0.12070069367619242 13278117.639252523 6440490.70393163 1913.7198279744189 0.02817384768329719 3.019642066025438e-11 10.520044533189456 0.36389960400960986 SHLEPSGNPLPATPTTSAPSAPPASS(ph)QGPDTAPRPSPPQEEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHLEPSGNPLPATPTTSAPSAPPASSQGPDTAPRPSPPQEEAR 43 1 Q8N1F8 Q8N1F8 STK11IP Serine/threonine-protein kinase 11-interacting protein 1 SHLEPSGNPLPATPTTSAPS(0.007)APPAS(0.143)S(0.419)QGPDT(0.335)APRPS(0.094)PPQEEAR 68.25 5.0436e-09 11531000.0 18721.0 21535.0 29308.0 28886.0 31412.0 21415.0 25093.0 20678.0 22281.0 19384.0 True False 21890.09554339559 23672.85248014311 30006.813871208964 27267.611069675564 25257.044092928754 20291.959701047064 22716.00938241232 20135.224410152015 22606.817473489304 22898.16575634042 0.9559759404455487 1.033831824437212 1.310446181170655 1.1908207565544966 1.1030160390002055 0.8861827587839998 0.9920449360063848 0.8793378746756886 0.9872763484223429 1.0 14.482944416290144 -6.67339034669948 6.035526849053487 0.9445784514146599 1.1313010812557118 0.44090147495555165 0.0953862270158739 0.2029222037165909 11.159745043800603 0.033985090179482196 0.03380444305842282 2.1213369334730374e-07 6.67339034669948 0.18672262984105192 SHLEPSGNPLPATPTTSAPSAPPASSQGPDTAPRPS(ph)PPQEEAR ddPTM_PC-9_Lapatinib_30min_R1 1 SHLEPSGNPLPATPTTSAPSAPPASSQGPDTAPRPSPPQEEAR 43 1 Q8N1F8 Q8N1F8 STK11IP Serine/threonine-protein kinase 11-interacting protein 1 SHLEPSGNPLPATPTT(0.001)SAPS(0.002)APPAS(0.049)S(0.049)QGPDT(0.164)APRPS(0.736)PPQEEAR 72.73100000000001 1.1232e-09 9264500.0 9277.2 12530.0 14172.0 11489.0 16646.0 16403.0 14292.0 14033.0 18143.0 12050.0 True False 9144.90542676988 12500.987554840913 13006.832865502012 12333.93938618048 15666.915007295174 15701.481927260567 15031.969828706917 14685.024409985173 16099.544285740183 14132.826444384273 0.6470684022588871 0.884535560104343 0.920327785576842 0.8727156902914783 1.1085478951395795 1.1109937554988942 1.063620917433676 1.0390720120829275 1.1391595551742866 1.0 13.78676240074268 -4.098499692972845 0.5399902180817635 1.083893405403824 5.5032266612078517e-14 0.8029033426127793 0.0635501709947376 3.516301135176771 0.45193916874100887 0.035169929670952595 2.8125541154590725 7.970770540886237e-05 4.098499692972845 -1.083893405403769 SHLGNVHDQDN ddPTM_PC-9_AZD4547_30min_R2 2 SHLGNVHDQDN 11 0 Q8WW12;Q8WW12-3 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 0 ; 128.51 0.00025691 20680300.0 9434.3 9885.3 15880.4 36462.0 22950.9 19028.7 13181.400000000001 20250.5 15863.3 16973.5 False True 12434.211154369506 13080.529907422497 15669.81551993097 28056.249232284394 19764.563696371108 17838.83238088645 14354.51906424463 17121.250535196385 16701.801652431186 16379.262931331306 0.7591435100894893 0.7986030850265685 0.9566862431859946 1.7129128062665504 1.2066821186785017 1.0891108138183183 0.8763837008066085 1.0453004269469144 1.0196918947117521 1.0 13.999582816550438 -5.526356267329677 24.9992510289523 1.1437431089929355 0.8035660272802468 0.3133114659022632 0.21216053866911216 124.93044138348029 898098.7730676043 0.06281226858692397 0.10947168997240676 2.9760740475685024e-06 5.526356267329677 -0.3401770817126887 SHLGNVHDQDN ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SHLGNVHDQDN 11 0 Q8WW12;Q8WW12-3 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 0 ;;; 127.51 0.00029917 18432200.0 29292.199999999997 28700.6 44783.0 51815.0 50079.0 44246.9 44942.3 42431.9 43544.0 33294.9 False True 34250.79091267838 31549.80589234251 45850.79656047327 48911.97353649655 40266.37944510945 41926.51467178428 40685.03998992505 41318.107585314334 44180.748622845385 39331.001807716624 0.8708344394614042 0.8021612580982499 1.1657673197502303 1.2435984665638538 1.0237821971066425 1.0659915269068592 1.0344267402297076 1.0505226331968958 1.123305956935408 1.0 15.26337931346866 -5.255828404154155 24.995983795498063 1.0907323615087459 0.8364978237326511 0.6676355972191826 0.07108536293880235 270.86070199571634 1206631.2602333948 0.019292109339540217 0.04816280311614462 5.548448966606219e-06 5.255828404154155 -0.2542345377760947 SHLGNVHDQDN ddPTM_PC-9_Lapatinib_30min_R1 3 SHLGNVHDQDN 11 0 Q8WW12;Q8WW12-3 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 0 ;; 136.49 6.880100000000001e-05 16506000.0 23013.3 18766.4 20988.5 17574.2 22987.8 22418.800000000003 20923.5 18878.6 26208.0 15940.4 False True 22685.126121877656 18722.947553804184 19262.906547952938 18866.665293812606 21635.70279975368 21460.00018477531 22006.81645052823 19755.768675717653 23256.17905752515 18695.676900752132 1.2133888621580227 1.0014586609084453 1.0303401503038376 1.0091458786952825 1.1572569912610797 1.1478589568432243 1.1771072300486156 1.0567025083174642 1.2439335136664427 1.0 14.190417086299382 -6.273772724257715 24.70599137166619 1.1365123168695683 1.0567713891137926 0.1297690511940245 0.08325076604367768 1104.9410139575632 2213400.958878796 0.02455647628864585 0.028058888188694203 5.323867959606679e-07 6.273772724257715 -0.07974092775577568 SHLIVTS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 1 SHLIVTSPPR 10 0 Q9H8N7 Q9H8N7 ZNF395 Zinc finger protein 395 1 S(0.001)HLIVT(0.248)S(0.751)PPR 67.118 0.025179 5527300.0 24577.0 26746.0 28921.0 26397.0 29270.0 25381.0 22085.0 23837.0 28583.0 19790.0 True False 24226.527473130183 26684.071280269356 26543.22701828843 28338.3234378106 27548.396147034102 24295.51379600077 23228.453237265065 24944.55404124679 25363.68154766643 23210.675131482563 1.0437666003204593 1.1496464936547899 1.1435784124299622 1.2209176716007275 1.1868847412227113 1.0467387811157096 1.0007659452248499 1.074701786998536 1.0927593188904516 1.0 14.502500866672868 -6.773580019840887 24.80518599480963 1.0450227915310377 1.152695792787974 0.528840678508675 0.04992934003162071 173.8628374075146 355226.22299227485 0.018448501291030504 0.016389783050490662 1.684302061328747e-07 6.773580019840887 0.10767300125693624 SHMS(ph)GSPGPGGSNTAPSTPVIGGSDKPGMEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHMSGSPGPGGSNTAPSTPVIGGSDKPGMEEK 32 1 A0A499FIX8;H7BXI1;A0A087WXU3;A0FGR8-5;A0FGR8-2;A0FGR8;A0FGR8-6 A0A499FIX8 ESYT2 Extended synaptotagmin-2 1 S(0.053)HMS(0.736)GS(0.211)PGPGGSNTAPSTPVIGGSDKPGMEEK 81.15100000000001 6.6145e-08 16589000.0 13476.0 15612.0 14878.0 17538.0 20301.0 15191.0 16074.0 10919.0 13925.0 12858.0 True False 15757.22063686763 17161.856183886444 15232.747945129217 16555.402718963167 16323.164781947873 14394.357217772875 14551.354354317757 10632.38781963681 14128.626781488198 15189.053616128009 1.0374063476961022 1.1298831788745336 1.0028766985821165 1.0899561708956207 1.074666348179563 0.94767966336551 0.9580158660357133 0.7000033108282105 0.9301847987741757 1.0 13.890744362236502 -7.058781946386615 1.8948603156209751 0.8661423042161672 1.0688016291589544 0.48677701947982366 0.08156978149727684 0.2564871755705364 1.8338972992322795 0.03651816300409625 0.026895292847650812 8.734097860159347e-08 7.058781946386615 0.20265932494278716 SHMS(ph)GSPGPGGSNTAPSTPVIGGSDKPGMEEK ddPTM_PC-9_Lapatinib_30min_R1 1 SHMSGSPGPGGSNTAPSTPVIGGSDKPGMEEK 32 1 A0A499FIX8;H7BXI1;A0A087WXU3;A0FGR8-5;A0FGR8-2;A0FGR8;A0FGR8-6 A0A499FIX8 ESYT2 Extended synaptotagmin-2 1 S(0.129)HMS(0.403)GS(0.155)PGPGGS(0.136)NT(0.136)APS(0.021)T(0.021)PVIGGSDKPGMEEK 47.085 0.00386 6218900.0 26755.0 29291.0 17923.0 11371.0 17703.0 25056.0 15521.0 17239.0 26474.0 8591.1 True False 26373.468793733908 29223.17848913367 16449.44012478074 12207.26127254401 16661.744345437124 23984.413288388776 16324.601435163735 18039.98687406358 23492.219336420967 10076.060188078822 2.6174385922125456 2.900258428756526 1.6325269815520143 1.2115113491468275 1.653597143569066 2.3803364450685986 1.620137348373294 1.7903810157274598 2.33148858759449 1.0 13.298644024517438 -5.262836077841202 24.99830088498699 1.7327106922736277 2.7588485743869824 0.5173626174274661 0.4072782616134144 93.41473892567427 1671987.7519257378 0.10625670907217592 0.24230062967683302 5.459638933943906e-06 5.262836077841202 1.0261378821133547 SHNVAAGSY(ph)EAPLPPGSFHGDFAYGTYR ddPTM_PC-9_AZD4547_30min_R2 1 SHNVAAGSYEAPLPPGSFHGDFAYGTYR 28 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0;X6RGP5 O15027 SEC16A Protein transport protein Sec16A 1 SHNVAAGS(0.006)Y(0.554)EAPLPPGS(0.44)FHGDFAYGT(0.001)YR 104.14 1.4711000000000002e-10 8862600.0 8447.2 7757.2 9799.8 15714.0 17988.0 11925.0 11162.0 12430.0 8009.5 10271.0 True False 11133.233887324977 10264.563199686174 9669.848248924427 12091.380078879856 15490.67669548137 11179.327864860494 12155.396376340792 10509.229112984425 8432.86581828167 9911.41541624909 1.1232738634961057 1.035630408837281 0.9756273794226574 1.2199448384593852 1.5629126663468733 1.1279244583505952 1.2264036836164538 1.0603156735571047 0.8508235669808131 1.0 13.274875383263538 -8.003233096326145 4.253865217405551 0.9288981084887461 1.1813383107579851 0.313780449360881 0.15182407108353524 0.27256945691498835 11.792833226352814 0.1108007489063654 0.04414576161524189 9.925831620972794e-09 8.003233096326145 0.252440202269239 SHNVAAGSY(ph)EAPLPPGSFHGDFAYGTYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHNVAAGSYEAPLPPGSFHGDFAYGTYR 28 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0;X6RGP5 O15027 SEC16A Protein transport protein Sec16A 1 SHNVAAGS(0.147)Y(0.569)EAPLPPGS(0.281)FHGDFAY(0.001)GT(0.001)YR 81.055 3.9586000000000005e-06 6913300.0 9159.3 12989.0 16389.0 20788.0 15937.0 16117.0 15612.0 16262.0 13788.0 12128.0 True False 10709.788585578932 14278.462078689528 16779.775915628627 19623.315755605334 12814.259254711755 15271.796147643041 14133.118338908107 15835.139731013249 13989.623415666729 14326.710394804832 0.7475399648940017 0.996632282304471 1.1712232224442345 1.369701432837029 0.8944313733987724 1.0659666962473757 0.9864873337589818 1.105287905921195 0.9764714320420452 1.0 13.80641976500989 -4.807046879841583 3.501313999720619 1.0764945821331737 0.7172443490379249 0.37901279029211066 0.12390303175926713 0.2894108169356316 5.914353916124833 0.0323364786624845 0.26598885521634347 1.559384166291599e-05 4.807046879841583 -0.35925023309524884 SHNVAAGSYEAPLPPGS(ph)FHGDFAYGTYR ddPTM_PC-9_AZD4547_30min_R2 3 SHNVAAGSYEAPLPPGSFHGDFAYGTYR 28 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0;X6RGP5 O15027 SEC16A Protein transport protein Sec16A 1 SHNVAAGSYEAPLPPGS(0.993)FHGDFAYGT(0.006)Y(0.001)R;SHNVAAGS(0.015)Y(0.037)EAPLPPGS(0.94)FHGDFAY(0.003)GT(0.003)Y(0.003)R;SHNVAAGSYEAPLPPGS(0.991)FHGDFAY(0.003)GT(0.003)Y(0.003)R 109.02 1.0445e-10 24893500.0 11505.899999999998 5008.8 18779.4 27603.3 29079.9 23664.6 21670.0 22437.800000000003 15156.400000000001 27375.0 True False 15164.5368624127 6627.79664757749 18530.372885758028 21239.785651733753 25042.657840612006 22184.84882102958 23598.588019647468 18970.5535793501 15957.536361596141 26416.609582301517 0.5740531090928704 0.2508950524831147 0.7014667354652857 0.8040314782092207 0.9479890961249613 0.8398068174461301 0.8933238743649354 0.71812976302833 0.60407208244798 1.0 14.689157696525026 -5.451785447109964 4.483249727165752 0.8223365804880627 0.41527511616350293 0.6206404932983478 0.12848899312339027 0.13655209970288795 5.1798830086909975 0.03434375331226104 0.07322208870153323 3.533576946680857e-06 5.451785447109964 -0.40706146432455975 SHNVAAGSYEAPLPPGS(ph)FHGDFAYGTYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SHNVAAGSYEAPLPPGSFHGDFAYGTYR 28 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0;X6RGP5 O15027 SEC16A Protein transport protein Sec16A 1 SHNVAAGSYEAPLPPGS(0.99)FHGDFAY(0.002)GT(0.006)Y(0.002)R;S(0.001)HNVAAGS(0.006)Y(0.107)EAPLPPGS(0.792)FHGDFAY(0.019)GT(0.055)Y(0.019)R 136.12 2.2359999999999998e-10 8775300.0 19026.9 11796.0 21300.4 26909.0 25684.6 26092.0 21003.8 23255.0 17420.6 20952.7 True False 22247.77837159519 12967.028922951857 21808.282318216843 25401.375970155077 20651.887008443842 24723.689587659115 19014.168009656558 22644.58089070922 17675.343318462703 24751.25864851806 0.8988544254466524 0.5238937181777717 0.8810979121468869 1.0262660307853047 0.8343772452832551 0.9988861551951582 0.7682101455796067 0.9148860351820947 0.71411896944162 1.0 14.595214270390377 -5.474519614105942 24.70756266889291 0.8920753200859602 0.7091542795051428 0.2442971948177658 0.12737012976897388 424.19574125202786 216728.14539177043 0.031166735972173936 0.06487635124959548 3.353361592719856e-06 5.474519614105942 -0.18292104058081748 SHNVAAGSYEAPLPPGS(ph)FHGDFAYGTYR ddPTM_PC-9_Lapatinib_30min_R1 4 SHNVAAGSYEAPLPPGSFHGDFAYGTYR 28 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0;X6RGP5 O15027 SEC16A Protein transport protein Sec16A 1 SHNVAAGSY(0.007)EAPLPPGS(0.974)FHGDFAY(0.002)GT(0.015)Y(0.003)R;SHNVAAGSYEAPLPPGS(0.596)FHGDFAY(0.107)GT(0.189)Y(0.107)R;SHNVAAGSYEAPLPPGS(0.984)FHGDFAY(0.005)GT(0.006)Y(0.005)R;SHNVAAGS(0.006)Y(0.428)EAPLPPGS(0.513)FHGDFAY(0.025)GT(0.015)Y(0.013)R 116.49 2.9419999999999998e-12 26898200.0 22534.0 18782.4 24808.7 20928.0 20163.300000000003 22698.6 21237.899999999998 19423.8 26362.100000000002 19744.6 True False 22212.6610277705 18738.910506787222 22769.0244503514 22467.114933761433 18977.334336573043 21727.83379102097 22337.494544157205 20326.30065806811 23392.92269278021 23157.427801974256 0.9592024303267735 0.8091965423374724 0.9832276989074865 0.9701904341831104 0.8194923244003445 0.9382662866023744 0.9645930772265153 0.8777443173691 1.01016930260216 1.0 14.499187395250468 -8.274789361543945 24.330271543786836 1.0050846876651998 0.9150235237169737 0.27289501664189 0.0586611871824973 812.7908417050832 1481285.1806455336 0.053946757335664876 0.014286553213536711 5.311419925235222e-09 8.274789361543945 -0.09006116394822605 SHPAMS(ph)PGTPGPTMGR ddPTM_PC-9_AZD4547_30min_R2 4 SHPAMSPGTPGPTMGR 16 0 A0A1B0GUC6;A0A1B0GUG2;A0A1B0GU09;A0A6I8PTU7;A0A3F2YNW7;Q8NFD5;Q8NFD5-2;Q8NFD5-3 A0A1B0GUC6 ARID1B AT-rich interactive domain-containing protein 1B 1 SHPAMS(0.998)PGT(0.002)PGPTMGR;S(0.004)HPAMS(0.993)PGT(0.003)PGPTMGR;S(0.001)HPAMS(0.957)PGT(0.041)PGPTMGR;SHPAMS(1)PGTPGPTMGR 86.573 0.0022635999999999997 15700900.0 29441.2 30028.5 45824.6 60020.0 46392.4 42002.9 37819.7 49522.0 38062.1 45400.0 True False 38802.88918499768 39734.62538567734 45216.93586273825 46183.316299756174 39951.61605111464 39376.452023056525 41185.58003353304 41869.512802350306 40073.98490068279 43810.55981868451 0.885697177703008 0.9069645663083071 1.0321013027424029 1.054159464998658 0.9119174969792535 0.8987890633221969 0.9400834000748843 0.9556945397555414 0.9147106329280886 1.0 15.418991029327405 SHPAMS(ph)PGTPGPTMGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SHPAMSPGTPGPTMGR 16 0 A0A1B0GUC6;A0A1B0GUG2;A0A1B0GU09;A0A6I8PTU7;A0A3F2YNW7;Q8NFD5;Q8NFD5-2;Q8NFD5-3 A0A1B0GUC6 ARID1B AT-rich interactive domain-containing protein 1B 1 SHPAMS(0.992)PGT(0.007)PGPTMGR;SHPAMS(1)PGTPGPTMGR;S(0.003)HPAMS(0.99)PGT(0.007)PGPTMGR;S(0.001)HPAMS(0.993)PGT(0.006)PGPTMGR 107.63 0.00045044 12970300.0 32461.8 31660.5 38584.6 37647.3 42470.9 37533.700000000004 39414.0 38756.8 35236.6 31253.699999999997 True False 37956.9415902248 34803.545203044894 39504.603196910364 35538.043835193384 34149.03202490663 35565.36669769746 35680.42058735101 37739.47506622399 35751.8686139021 36919.74840584691 1.0280931812691776 0.942680996101618 1.0700127953920209 0.962575460822081 0.9249529993952642 0.9633155217294231 0.9664318455025106 1.022202931920502 0.9683670706770078 1.0 15.172105101144357 -1.5228818373238437 0.6980583837029991 0.977107295212191 5.505919201584092 0.07664307606193299 0.04040884978115298 906.2213541904628 4.8467344830727175 0.016333998765784445 6403.400620436418 0.029999786409961822 1.5228818373238437 4.528811906371901 SHPAMS(ph)PGTPGPTMGR ddPTM_PC-9_Lapatinib_30min_R1 1 SHPAMSPGTPGPTMGR 16 0 A0A1B0GUC6;A0A1B0GUG2;A0A1B0GU09;A0A6I8PTU7;A0A3F2YNW7;Q8NFD5;Q8NFD5-2;Q8NFD5-3 A0A1B0GUC6 ARID1B AT-rich interactive domain-containing protein 1B 1 S(0.026)HPAMS(0.968)PGT(0.005)PGPTMGR 55.536 0.033144 1308800.0 4587.6 4215.8 4729.3 4125.7 4529.8 3587.3 4414.3 4013.4 5306.7 4305.5 True False 4522.179982737199 4206.038574117978 4340.47520962593 4429.117740931744 4263.366069929451 3433.879541404735 4642.850854664219 4199.8772156370305 4709.003563971636 5049.699938281866 0.8955343957082422 0.8329284166435166 0.859551114457457 0.8771051339812339 0.8442810705659551 0.6800165521464815 0.9194310377665578 0.8317082731585071 0.9325313625612872 1.0 12.301981947692022 -8.475149971013733 1.9765837213617032 1.000788648413263 0.8395338265664672 0.4151623284375492 0.060982777072743924 0.31811761081122175 2.7578038039770867 0.058273766228066855 0.0164086573744639 3.3484978851995806e-09 8.475149971013733 -0.16125482184679585 SHPAMSPGT(ph)PGPTMGR ddPTM_PC-9_AZD4547_30min_R2 3 SHPAMSPGTPGPTMGR 16 0 A0A1B0GUC6;A0A1B0GUG2;A0A1B0GU09;A0A6I8PTU7;A0A3F2YNW7;Q8NFD5;Q8NFD5-2;Q8NFD5-3 A0A1B0GUC6 ARID1B AT-rich interactive domain-containing protein 1B 1 SHPAMSPGT(0.983)PGPT(0.017)MGR;SHPAMSPGT(0.999)PGPT(0.001)MGR;SHPAMS(0.153)PGT(0.838)PGPT(0.009)MGR 94.911 0.0031191 2235800.0 4432.07 4656.1 9193.8 13838.300000000001 9813.1 8321.4 5984.5 12064.2 7831.799999999999 9875.2 True False 5841.376067217118 6161.093270001909 9071.884204877795 10648.093734603739 8450.720451435865 7801.061542528307 6517.108906487326 10199.955097736663 8245.772959063408 9529.472253776945 0.6129800173248762 0.6465303750226042 0.9519818058426281 1.117385459659997 0.8867983689323905 0.8186247186392097 0.6838898034363143 1.0703588641746637 0.8652916698293811 1.0 13.218180603945138 -5.248025354744467 11.123841396811882 0.9200102625784711 0.6295542637780193 0.498172566143426 0.11818358052308399 0.5085901246328195 411.37103235028405 0.032005358042487116 0.08024970752727792 5.649039939315451e-06 5.248025354744467 -0.2904559988004518 SHPAMSPGT(ph)PGPTMGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHPAMSPGTPGPTMGR 16 0 A0A1B0GUC6;A0A1B0GUG2;A0A1B0GU09;A0A6I8PTU7;A0A3F2YNW7;Q8NFD5;Q8NFD5-2;Q8NFD5-3 A0A1B0GUC6 ARID1B AT-rich interactive domain-containing protein 1B 1 SHPAMS(0.014)PGT(0.969)PGPT(0.016)MGR 75.319 0.015283000000000001 695380.0 2383.6 2388.1 2311.5 3090.0 3944.1 3967.9 3197.9 3254.3 2642.7 3370.1 True False 2787.096401754059 2625.1747855969256 2366.6149264125675 2916.8773179151644 3171.2819179587523 3759.81633891126 2894.9717612089576 3168.8780732158675 2681.3444880027896 3981.072452303078 0.7000868321654645 0.659413968735546 0.594466680716515 0.73268631828786 0.7965898525971673 0.9444229875133723 0.7271838922535048 0.7959860342111206 0.6735231574224713 1.0 11.958941412214735 -6.061946285959539 3.268379703985321 0.8135657596902076 0.6524869683727832 0.4067690427068408 0.09261682776935751 0.264111502251062 5.5637836283536 0.027741969346802137 0.038854863991377275 8.670691092302615e-07 6.061946285959539 -0.16107879131742442 SHPLDLS(ph)PNVQSR ddPTM_PC-9_AZD4547_30min_R2 3 SHPLDLSPNVQSR 13 0 H0YBF7;A0A0A0MRE5;Q9ULH1;Q9ULH1-2;H0YBM4 H0YBF7 ASAP1 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 1 SHPLDLS(1)PNVQSR;SHPLDLS(0.995)PNVQS(0.005)R;SHPLDLS(1)PNVQSR 169.15 7.8081e-05 30184600.0 93748.0 88433.0 139269.0 191860.0 169415.0 153255.0 106355.0 154077.0 120362.0 150601.0 True False 123557.91392046398 117017.23784843084 137422.20206325204 147629.64120745115 145894.65156576512 143671.94062299308 115820.3889630647 130267.9399872326 126724.089596107 145328.5048293769 0.8501973791413273 0.8051912320010108 0.9455970267126379 1.01583403325298 1.0038956344940926 0.9886012437248376 0.7969557596360312 0.8963688172542188 0.8719837154100468 1.0 17.14895817632496 -5.266250951233552 24.305083994840015 0.9378344390254213 0.8276943002692879 0.3143559766373303 0.06623095850561149 333.3790539899641 1684038.233140235 0.019127753916937492 0.042000943191793066 5.41687792934773e-06 5.266250951233552 -0.11014013875613338 SHPLDLS(ph)PNVQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SHPLDLSPNVQSR 13 0 H0YBF7;A0A0A0MRE5;Q9ULH1;Q9ULH1-2;H0YBM4 H0YBF7 ASAP1 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 1 SHPLDLS(0.987)PNVQS(0.013)R;SHPLDLS(0.921)PNVQS(0.079)R;SHPLDLS(0.999)PNVQS(0.001)R 136.14 5.4000000000000005e-05 17504100.0 91270.0 100281.0 96606.0 103576.0 118811.0 98799.0 120401.0 87429.0 94766.0 88205.0 True False 106720.20833533011 110236.23494595916 98909.45342029506 97772.97251792268 95530.8374418997 93617.80651430062 108995.74565224687 85134.08138868252 96151.7734703417 104195.86826960395 1.0242268729811292 1.057971268694896 0.9492646403633738 0.9383574813632514 0.9168390170204856 0.8984790670592343 1.0460659089688986 0.8170581310230116 0.9227983322865704 1.0 16.668938545286103 -5.352722249926087 4.183911654492506 0.9300016171487046 1.041191803726147 0.34677268146130236 0.057545796832126524 0.22368962412379376 6.925379776199604 0.014960624048143117 0.03380788904198161 4.438924415548901e-06 5.352722249926087 0.1111901865774424 SHPLDLS(ph)PNVQSR ddPTM_PC-9_Lapatinib_30min_R1 2 SHPLDLSPNVQSR 13 0 H0YBF7;A0A0A0MRE5;Q9ULH1;Q9ULH1-2;H0YBM4 H0YBF7 ASAP1 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 1 SHPLDLS(0.998)PNVQS(0.002)R;SHPLDLS(1)PNVQSR 175.7 6.598300000000001e-05 24468000.0 181448.0 185962.0 187063.0 174666.0 188765.0 195009.0 179453.0 175773.0 211584.0 140758.0 True False 178860.518246512 185531.4164144711 171683.4022240619 187511.52030869562 177662.21382626903 186668.9196581817 188744.19826972726 183940.05527088422 187753.18184170467 165087.8327517545 1.0834264116572887 1.123834587455382 1.0399518811433262 1.1358288323444163 1.0761678245144985 1.1307248786703685 1.1432956331406037 1.114195105750029 1.1372926684671696 1.0 17.332874269578625 -4.697436834818192 21.308298716285787 1.1045011830768627 1.0834228883639527 0.0038964783713351103 0.04539497383420004 28328.298836610993 9424366.282451203 0.010576997209851745 20.81447250393763 2.0070729839201938e-05 4.697436834818192 -0.021078294712910006 SHPLDPIDTVDFER ddPTM_PC-9_Lapatinib_30min_R1 2 SHPLDPIDTVDFER 14 0 A0A1B0GVU9;A0A0U1RQL2;C9J165;A0A0U1RQT0;P47897-2;P47897;A0A0U1RQM8;A0A0U1RQU2;A0A0U1RRI9;A0A0U1RQE9 A0A1B0GVU9 QARS Glutamine--tRNA ligase 0 ; 123.95 3.327e-05 5610500.0 30379.0 30128.0 47413.0 29918.0 37350.0 45804.0 34526.0 29126.0 40620.0 29695.0 False True 29945.789889173695 30058.240467058815 43514.886159472684 32118.269523522275 35153.146432925285 43845.069694339065 36313.58734298457 30479.300289690564 36044.94785243713 34827.74118389965 0.859825784596596 0.8630545491981058 1.2494317656061191 0.9222036351404287 1.0093432774553885 1.258912240757319 1.0426627196762277 0.8751443318919774 1.0349493428847512 1.0 15.087949286913904 -5.075014469117474 24.999990368101606 1.0466233915105025 0.8606250805894137 0.2945770523421908 0.11610309762907077 143.00833237184816 47659.48857475551 0.030097943102299216 0.07963175867559717 8.41367109876763e-06 5.075014469117474 -0.18599831092108887 SHQDFSR ddPTM_PC-9_AZD4547_30min_R2 2 SHQDFSR 7 0 Q07065 Q07065 CKAP4 Cytoskeleton-associated protein 4 0 ; 101.72 0.0093225 2562900.0 5549.2 4770.9 8951.7 6651.9 6137.200000000001 4792.2 7777.5 6445.5 7789.8 7247.3 False True 7313.730169469624 6313.00012496555 8832.994609063126 5118.407225830523 5285.155715783204 4492.542976434754 8469.68243298607 5449.496077855274 8201.552924808107 6993.574232906437 1.0457785855845751 0.9026857962358327 1.2630157791850949 0.7318728672024664 0.7557159672253544 0.6423815386553368 1.211066351899747 0.7792147328921016 1.172726942143238 1.0 12.771814252448955 -10.299804806901104 18.457347877448914 0.9999999999934314 0.9352743740108924 0.00430213740800689 0.20901836786058234 0.0 0.0 0.20032630185099345 0.04858626483064781 5.014125422163283e-11 10.299804806901104 -0.06472562598253895 SHQDFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SHQDFSR 7 0 Q07065 Q07065 CKAP4 Cytoskeleton-associated protein 4 0 ; 98.523 0.010185 1508440.0 2773.17 2792.46 5430.4 3106.7 7115.2 5032.3 3089.71 2853.01 2489.5 2814.7799999999997 False True 3242.612908395828 3069.676974074784 5559.8813309066845 2932.6416710572958 5721.027636890569 4768.397329142151 2797.030301236724 2778.121510513966 2525.904227828716 3325.077332213781 0.9751992463396183 0.9231896486542899 1.6721058716565271 0.8819769822029347 1.7205697989230235 1.4340711065409812 0.8411925563771799 0.835505834285165 0.7596527766008411 1.0 11.699172178810935 -7.275435512982748 23.740163040858707 0.8453798498314582 1.2735990943771103 0.3387564190448423 0.27944775052105075 484.7388283379264 822206.194521748 0.11796691865828864 0.08005102209193869 5.303523371278839e-08 7.275435512982748 0.4282192445456521 SHQDFSR ddPTM_PC-9_Lapatinib_30min_R1 2 SHQDFSR 7 0 Q07065 Q07065 CKAP4 Cytoskeleton-associated protein 4 0 ; 98.62899999999999 0.010156 2246600.0 11378.6 13822.1 4598.200000000001 4526.7 5575.1 6593.5 6862.700000000001 5793.3 10396.099999999999 1619.78 False True 11216.339077420322 13790.095776677292 4220.153745565296 4859.608618628531 5247.183579068323 6311.511375199208 7218.0170265510105 6062.477867481439 9225.181742213723 1899.7568147788188 5.904092034393463 7.2588742250585465 2.221417874506549 2.558016152817073 2.762029086169764 3.3222733173530066 3.7994426288668826 3.1911862720109623 4.85598033940348 1.0 10.891599037656698 -5.259816875629209 24.99993621154291 3.0629994106068357 6.581483360242954 0.6744790374045667 1.00341027588399 77.83942059635098 1199342.260698078 0.25249324869773265 0.5998886143442468 5.497726418183816e-06 5.259816875629209 3.5184839496361184 SHRGEGEEDHES(ph)PSSGR ddPTM_PC-9_AZD4547_30min_R2 1 SHRGEGEEDHESPSSGR 17 1 Q9NTX7-2;Q9NTX7 Q9NTX7-2 RNF146 E3 ubiquitin-protein ligase RNF146 1 SHRGEGEEDHES(0.924)PS(0.063)S(0.013)GR 62.617 0.011895999999999999 10551000.0 3909.7 3073.0 4763.9 5927.3 5182.0 5934.8 2718.2 5568.9 6746.7 5526.1 True False 5152.903273188095 4066.287154209716 4700.727573323039 4560.852560872125 4462.568747831023 5563.696017809143 2960.1145341488586 4708.354465591226 7103.3167883389615 5332.632921013932 0.9662962648117802 0.7625289822942779 0.8815021853087266 0.8552721757575875 0.8368415403666154 1.0433300210642058 0.555094374203809 0.8829324154372868 1.3320468319406384 1.0 12.380632306240152 -8.145674586327626 6.825331227950614 1.162352270616683 0.8407208086447978 0.4461273784450712 0.14213402480122447 0.20056666954612418 10.338071015956244 0.09250500519857502 0.034413663860285194 7.150318935594822e-09 8.145674586327626 -0.3216314619718851 SHS(ph)APSEVGFSDAR ddPTM_PC-9_AZD4547_30min_R2 2 SHSAPSEVGFSDAR 14 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 S(0.204)HS(0.796)APSEVGFSDAR;S(0.173)HS(0.826)APSEVGFSDAR 96.096 0.0017197 14796100.0 35959.0 32962.0 61596.0 79497.0 83776.0 65009.0 53777.0 69880.0 50940.0 65094.0 True False 47393.214006335715 43616.32189295825 60779.19679388856 61170.1948664065 72145.14847902191 60943.97695318375 58563.04882014685 59081.65168265103 53632.584403928835 62815.0788730716 0.754487853180948 0.6943606961171273 0.9675892776749212 0.9738138670495206 1.1485323233423503 0.9702125356927638 0.9323087683847903 0.940564793399932 0.8538170351151269 1.0 15.93882330178935 -5.267031873664078 23.89992755408146 0.9759267333337627 0.724424258821725 0.6630819063769207 0.07095791282118931 136.77345285015406 584516.5942562625 0.019900086736200074 0.04344620170134424 5.4071463745592376e-06 5.267031873664078 -0.25150247451203767 SHS(ph)APSEVGFSDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SHSAPSEVGFSDAR 14 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 S(0.182)HS(0.815)APS(0.003)EVGFSDAR;S(0.228)HS(0.77)APS(0.003)EVGFSDAR 79.317 0.0073196 12122000.0 42611.0 51803.0 64656.0 74836.0 87526.0 80252.0 73253.0 72061.0 79139.0 51608.0 True False 49824.20069438756 56945.659485899894 66197.64424924542 70643.18154158554 70375.90861064813 76043.44384442824 66313.94553420674 70169.47510494059 80296.25815872125 60964.1218712968 0.8172708662903886 0.9340847983691063 1.085845940486066 1.1587664904076285 1.1543823883696847 1.2473474809489729 1.0877536409727038 1.1509962409214636 1.3171067784464625 1.0 15.895672828349277 -5.12558979222422 1.4415862460608548 1.1687112346274156 0.7767858065971494 0.6730757995207373 0.0799371183574173 0.3689865969648494 1.0816675394313917 0.022811467174168293 0.17366608219005378 7.488765091122083e-06 5.12558979222422 -0.3919254280302662 SHS(ph)APSEVGFSDAR ddPTM_PC-9_Lapatinib_30min_R1 1 SHSAPSEVGFSDAR 14 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 S(0.087)HS(0.913)APSEVGFSDAR 104.78 0.00058592 5508300.0 26119.0 28046.0 42319.0 31356.0 41305.0 28727.0 29139.0 27229.0 41357.0 26043.0 True False 25746.53827036202 27981.061210141106 38839.69517606404 33662.02484054965 38875.521108754496 27498.41317590772 30647.674841778004 28494.158744351596 36698.93915148303 30544.497849883774 0.842919022499497 0.9160753385980964 1.2715774659956254 1.102065092246319 1.272750375528024 0.9002738663786007 1.0033779239849125 0.9328737006707747 1.20149099624575 1.0 14.898624902323562 -5.021220760082754 22.61375933841384 1.0817407798873384 0.861207812260682 0.31087220693672435 0.12470936015688835 234.4375176994658 249833.0642457398 0.03253489914078253 0.08857712896042803 9.523119628235371e-06 5.021220760082754 -0.22053296762665642 SHS(ph)DNDRPNCSWNTQYSSAYYTSR ddPTM_PC-9_AZD4547_30min_R2 1 SHSDNDRPNCSWNTQYSSAYYTSR 24 1 O75494-6;O75494-3 O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 1 S(0.197)HS(0.762)DNDRPNCS(0.04)WNTQYSSAYYTSR 65.111 0.00056652 13439000.0 2719.5 3365.5 6271.3 10482.0 7759.7 8701.9 6916.8 10825.0 5698.9 7178.2 True False 3584.2444308860095 4453.332059060461 6188.13846440537 8065.5368452856455 6682.399597171821 8157.768817377733 7532.3818003829065 9152.24498375353 6000.132219465062 6926.893402874034 0.5174389473640337 0.6429046615922703 0.8933497463434116 1.1643801017551645 0.9647036858397777 1.1776951575424848 1.087411248057845 1.3212625706000003 0.8662082510141631 1.0 12.757992757206358 -5.32976275587461 1.922721442431925 1.0976390244017773 0.5219417595167563 0.7309080454867662 0.12132908948348357 0.17678286481063518 1.1930372354562975 0.03292645117171697 0.11936177117030368 4.679907230042229e-06 5.32976275587461 -0.575697264885021 SHS(ph)DTSIASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SHSDTSIASR 10 0 E9PEM3;H7C357;H0Y6E6;Q92622-3;Q92622-2;Q92622;H7C3H3 E9PEM3 KIAA0226 Run domain Beclin-1 interacting and cysteine-rich containing protein 1 S(0.007)HS(0.983)DT(0.008)S(0.002)IASR;S(0.31)HS(0.69)DTSIASR 89.44 0.0052976 22152000.0 16859.8 18941.7 23390.8 23812.3 25281.0 24903.0 24824.0 19906.3 23558.0 22379.8 True False 19713.831143771215 20822.10679466576 23948.52538210299 22478.17403151822 20327.369531177003 23597.042840774007 22472.491009803663 19383.780717468282 23902.49118264264 26437.08058160067 0.7456886581301033 0.7876099151869763 0.9058687591537763 0.8502517500802371 0.7688961520707464 0.8925737003350047 0.8500367860377054 0.7332042831899809 0.9041274852140059 1.0 14.690275249927868 -14.52287873998337 0.2865748449938335 2.325189474375273 0.8163195674837982 0.4407144004280199 0.060282286368976985 237.702308369271 2.250935692037943 187.90741905390547 0.06666423371915532 3.0000000365901616e-15 14.52287873998337 -1.5088699068914746 SHS(ph)FCK ddPTM_PC-9_Lapatinib_30min_R1 1 SHSFCK 6 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 S(0.002)HS(0.998)FCK 64.207 0.045862 19258000.0 29435.0 51866.0 44209.0 54596.0 62897.0 34431.0 57808.0 62841.0 62622.0 44625.0 True False 29015.251502282103 51745.90746363753 40574.30667167502 58611.17196691701 59197.52212025982 32958.466392581184 60801.01538328362 65760.82227234927 55568.850921105775 52338.37179092519 0.5543781839104321 0.9886801154293763 0.7752305867243292 1.1198508849501398 1.1310539494185012 0.6297189856084855 1.1616909984545172 1.256455254952187 1.0617229581211525 1.0 15.67558142342918 -4.27293540952195 0.7513105074070117 1.0560876426591908 2.3797498496985091e-29 0.37046074834338494 0.17799855259037434 6.453974690560193 1.620865010705538 0.0712930844138068 6.849766464594093 5.334142216570519e-05 4.27293540952195 -1.0560876426591908 SHS(ph)GPAGSFNKPAIR ddPTM_PC-9_AZD4547_30min_R2 1 SHSGPAGSFNKPAIR 15 1 Q9UJM3 Q9UJM3 ERRFI1 ERBB receptor feedback inhibitor 1 1 S(0.008)HS(0.992)GPAGSFNKPAIR 68.123 0.041469 0.0 16180.0 16025.0 17462.0 32825.0 29403.0 19581.0 16030.0 19538.0 20591.0 21361.0 True False 21324.903435093063 21204.76786404513 17230.442470531885 25257.703391194547 25320.900982723964 18356.596974577216 17456.638945775223 16518.851038575194 21679.39822264035 20613.157891782368 1.0345286999229963 1.0287005986840383 0.835895332534224 1.2253194548741981 1.2283853408418506 0.8905281311552583 0.8468687348838714 0.8013741089695233 1.051726200151169 1.0 14.331277919158357 -6.8238244930643495 24.999935443308562 0.9012327045444873 1.0638018899661272 0.2700128152686506 0.12355210770391235 92.0279289026603 36877.772953089705 0.04588288788445775 0.0404649174372707 1.5002910100941082e-07 6.8238244930643495 0.1625691854216399 SHS(ph)GSSSPSPSR ddPTM_PC-9_AZD4547_30min_R2 1 SHSGSSSPSPSR 12 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.04)HS(0.872)GS(0.07)S(0.018)SPSPSR 85.976 0.0053118 1199100.0 624.78 692.24 2962.8 5055.6 2390.5 3363.0 2529.0 1162.4 2549.0 3312.8 True False 823.4470437686931 915.9930425089922 2923.5113361408717 3890.109528241375 2058.6203380335915 3152.7110783669486 2754.0761006778253 982.7777892946983 2683.734936113361 3196.8198803378423 0.2575831840990899 0.2865325782484152 0.9145061171954151 1.2168685361873641 0.6439588137871675 0.9862022873912333 0.8615049342056683 0.3074235728260166 0.839501453497512 1.0 11.642421744744281 -5.2551059295233244 23.675215849462493 0.8330662655235005 0.2720576890073646 0.503604765777771 0.2277246680121166 207.48252246729152 775582.2952260532 0.06120830030799004 0.15325936911827365 5.557686822298527e-06 5.2551059295233244 -0.5610085765161359 SHS(ph)GSSSPSPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHSGSSSPSPSR 12 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.068)HS(0.868)GS(0.059)S(0.005)SPSPSR 79.346 0.008775100000000001 767980.0 0.0 783.18 2222.5 1258.1 2663.8 2938.8 2650.0 2317.2 2333.0 2381.6 True False 0.0 860.9289345436962 2275.4928288781875 1187.6127358152335 2141.847512248301 2784.684154538273 2398.972815661445 2256.375955276343 2367.115711397626 2813.3652272647746 0.0 0.306013924605414 0.8088152959402571 0.4221324427791627 0.7613115750103515 0.9898054214758366 0.8527057889294337 0.8020202757215598 0.8413823020408183 1.0 11.458081138189472 -5.2860239025945726 0.8560046535376986 0.8684147866885318 3.9407399653977726e-23 0.7686565640403917 0.1491106308240551 0.6767652589211566 0.6309521701778104 0.060644085634277124 0.48121221944171133 5.175783448149804e-06 5.2860239025945726 -0.8684147866885318 down SHS(ph)ITNMEIGGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHSITNMEIGGLK 13 0 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 S(0.004)HS(0.642)IT(0.354)NMEIGGLK 106.42 0.0018983000000000001 0.0 20236.0 23856.0 29089.0 20595.0 60188.0 30221.0 26951.0 32517.0 25731.0 19921.0 True False 23661.555120781624 26224.26602118851 29782.59208064683 19441.12891989089 48394.59346317319 28636.15755897005 24398.006171657216 31663.46320460942 26107.26719673055 23532.519605450754 1.0054832851515392 1.1143841144453683 1.2655929998141124 0.8261388600049359 2.056498593204772 1.2168759673459344 1.0367783212642472 1.3455194656366216 1.1094123210964377 1.0 14.522368176426262 SHS(ph)ITNMEIGGLK ddPTM_PC-9_Lapatinib_30min_R1 2 SHSITNMEIGGLK 13 0 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 S(0.001)HS(0.95)IT(0.049)NMEIGGLK;S(0.001)HS(0.999)ITNMEIGGLK 104.81 0.0028871 0.0 97557.0 105502.0 51300.0 32136.0 50131.0 39547.0 39715.0 34125.0 66394.0 27284.0 True False 96165.8192902373 105257.71660102368 47082.3120237266 34499.38864255339 47182.393141338114 37855.666998559675 41771.248373012575 35710.572079437305 58916.0085601848 32000.00304635522 3.0051815667308355 3.2893033306449158 1.47132211067365 1.0781057924456308 1.474449645301273 1.1829894810860466 1.3053513873890175 1.1159552712450356 1.8411250922332425 1.0 14.96578442200463 -5.292321085296109 5.664483642889757 1.2984331463041037 3.1551321099859857 0.9048072871142905 0.23874556682855935 0.04108271857060368 4.103478575736081 0.05836467736927793 0.13052140034397186 5.101277097327904e-06 5.292321085296109 1.856698963681882 SHS(ph)LSGAR ddPTM_PC-9_AZD4547_30min_R2 2 SHSLSGAR 8 0 A0A0J9YYJ3;Q9Y519 A0A0J9YYJ3 TMEM184B Transmembrane protein 184B 1 S(0.039)HS(0.949)LS(0.012)GAR;S(0.01)HS(0.872)LS(0.118)GAR 79.48899999999999 0.014773 30563000.0 27004.5 30018.0 36130.0 51061.0 38640.0 32058.0 39729.0 32050.0 46948.0 43957.0 True False 35591.369271506235 39720.731466016055 35650.892593077384 39289.675334585976 33275.50297494997 30053.408192175924 43264.80403472885 27097.408935732146 49429.57543375837 42418.07880946952 0.8390613217390865 0.936410431137883 0.8404645753338217 0.9262483459249655 0.7844651127273936 0.7085046997806681 1.0199614232663055 0.6388174499238011 1.1652950067772418 1.0 15.372391659663146 -8.280934525344051 24.998879145829637 1.0826475256182606 0.8432618119678253 0.4376400043419527 0.11130451202461256 845.9013618137988 1084699.695956368 0.09934650173954669 0.025807829100389215 5.2367938104448605e-09 8.280934525344051 -0.23938571365043526 SHS(ph)LSGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SHSLSGAR 8 0 A0A0J9YYJ3;Q9Y519 A0A0J9YYJ3 TMEM184B Transmembrane protein 184B 1 S(0.036)HS(0.961)LS(0.003)GAR;S(0.001)HS(0.981)LS(0.018)GAR;S(0.078)HS(0.919)LS(0.003)GAR 92.23899999999999 0.0081241 39188000.0 49584.8 61082.0 69587.0 52507.1 107572.0 75753.0 60910.0 82621.0 77727.0 73476.0 True False 57978.52729555905 67145.81728312536 71246.2179901671 49565.29741731501 86494.03881206326 71780.379324465 55140.16384978814 80452.28629418554 78863.61032996286 86796.61716430388 0.6679814166698123 0.7735994728460438 0.8208409534590473 0.5710510275243689 0.9965139384214957 0.8269951257269219 0.635280102511474 0.9269057818450611 0.9086023500279505 1.0 16.405351195313827 -9.604481817955545 0.08277023674450554 1.3797011052004582 0.46339710031123743 0.3305627375890363 0.11678203700121255 62.411038094629355 1.5529693359371803 11.074465323494282 5.983957594988193 2.486097644278908e-10 9.604481817955545 -0.9163040048892208 SHS(ph)LSGAR ddPTM_PC-9_Lapatinib_30min_R1 3 SHSLSGAR 8 0 A0A0J9YYJ3;Q9Y519 A0A0J9YYJ3 TMEM184B Transmembrane protein 184B 1 S(0.233)HS(0.757)LS(0.01)GAR;S(0.002)HS(0.996)LS(0.002)GAR;SHS(0.999)LS(0.001)GAR 91.265 0.0088545 40739000.0 49719.9 62165.6 60734.4 42186.7 59505.3 50870.9 65523.5 63683.2 78410.9 50517.3 True False 49010.88510848704 62021.65937264311 55741.05207356378 45289.25064870571 56005.31524592104 48695.270192859854 68915.98622105221 66642.15395895155 69579.43873861793 59249.147994928935 0.8271998293153823 1.0467941138655947 0.9407907786004718 0.7643865301249896 0.9452509806675105 0.821872918696276 1.1631557339347842 1.1247782662571852 1.1743534058004201 1.0 15.85450678769826 -7.267270109491622 24.988900036127937 1.1259700507332076 0.897095810333649 0.6179797900702133 0.08624792734297135 321.9636428152053 1379840.5255504106 0.03521250430737841 0.02446594109743617 5.4041810531249146e-08 7.267270109491622 -0.2288742403995585 SHS(ph)LSQHTATSSK ddPTM_PC-9_AZD4547_30min_R2 1 SHSLSQHTATSSK 13 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 S(0.145)HS(0.748)LS(0.107)QHTATSSK 75.445 0.010401 3268000.0 4464.1 5180.7 19436.0 42003.0 25768.0 20083.0 11964.0 29471.0 14165.0 22073.0 True False 5883.590940951733 6855.259960889774 19178.2659407432 32319.857289881027 22190.557988056695 18827.206835219575 13028.772822660929 24916.934126207892 14913.732981579362 21300.2309884983 0.2762219313081043 0.3218397004516748 0.9003783081553942 1.517347737089476 1.0417989363607913 0.8838968387425419 0.6116728419375455 1.1697964280135056 0.7001676643615968 1.0 14.378581455266012 -5.279699318793024 4.680956490913358 0.9932875234676334 0.28748984319856596 0.5728582465986152 0.2354116341808622 0.13092997387669408 7.898046531431553 0.06495299292667552 0.1557527792948071 5.251709333898224e-06 5.279699318793024 -0.7057976802690674 SHS(ph)LSQHTATSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHSLSQHTATSSK 13 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 S(0.019)HS(0.936)LS(0.045)QHTATSSK 89.484 0.0034476999999999997 1678100.0 5521.7 5022.3 13973.0 14701.0 17902.0 22163.0 13976.0 14032.0 15980.0 12481.0 True False 6456.414751453846 5520.880752775615 14306.169312897593 13877.350631285062 14394.231610582285 21000.73326426832 12652.0921025224 13663.67486813294 16213.677268810143 14743.70650045837 0.4379098804804017 0.3744567726306798 0.9703237996804146 0.941238936820509 0.9762966734406155 1.424386280587953 0.8581351034171127 0.9267462606982951 1.0997015756048911 1.0 13.847811636521397 -5.293571719333286 4.7992337209664955 1.029537132315547 0.40032971711305354 0.7393018844900838 0.1470551204292771 0.0904429795859554 5.413551870893535 0.04001817210823812 0.09273239593211528 5.086608125291324e-06 5.293571719333286 -0.6292074152024936 down SHS(ph)LSRPGPTEGDAEGEAEGPVGSTLGSYATLTR ddPTM_PC-9_AZD4547_30min_R2 1 SHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTR 34 1 Q8WXE0-2;Q8WXE0 Q8WXE0-2 CASKIN2 Caskin-2 1 S(0.193)HS(0.574)LS(0.166)RPGPT(0.067)EGDAEGEAEGPVGSTLGSYATLTR 74.476 2.6440999999999998e-08 3724700.0 3139.7 3002.8 4300.2 6929.7 3791.7 3847.1 3855.9 4048.6 3272.2 3519.3 True False 4138.05929018305 3973.396377045539 4243.176538299233 5332.164727797743 3265.287904506154 3606.5402288389782 4199.067630131918 3422.981897572704 3445.1618116712993 3396.09037819155 1.2184773752654383 1.1699913531634014 1.249429804797705 1.570089171371573 0.9614843955492582 1.0619682715156404 1.2364416615932232 1.0079183756574446 1.0144493897438267 1.0 11.7296591376737 -6.29968132849795 24.99998517583612 1.0576557219824299 1.2888134757923686 0.509895692635961 0.12191381498275225 520.4404614237358 340227.2408872802 0.03936710683965611 0.04463904655179252 5.015551238632852e-07 6.29968132849795 0.23115775380993875 SHS(ph)LSRPGPTEGDAEGEAEGPVGSTLGSYATLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTR 34 1 Q8WXE0-2;Q8WXE0 Q8WXE0-2 CASKIN2 Caskin-2 1 S(0.242)HS(0.73)LS(0.021)RPGPT(0.006)EGDAEGEAEGPVGSTLGSYATLTR 80.583 9.369299999999999e-09 7810300.0 11087.0 5996.2 13740.0 17602.0 16149.0 15810.0 14571.0 17864.0 14722.0 13328.0 True False 12963.810121768442 6591.463108494739 14067.61370924018 16615.817006453966 12984.71937656648 14980.895768085657 13190.729395095444 17395.088928472556 14937.281398712323 15744.26089561006 0.8233990917530536 0.41865814801967766 0.893507405810496 1.055357067354424 0.8247271474132509 0.9515147054164194 0.8378119165170459 1.1048526852932674 0.9487445296893711 1.0 13.942538412204346 -5.425416804434927 6.867444539507611 0.9552065485788545 0.6237085283233083 0.5482328829035841 0.12140634727542444 0.16692371420225402 10.080380144992091 0.029942126252081706 0.06275869935513516 3.7547687576118785e-06 5.425416804434927 -0.3314980202555462 SHS(ph)LSRPGPTEGDAEGEAEGPVGSTLGSYATLTR ddPTM_PC-9_Lapatinib_30min_R1 2 SHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTR 34 1 Q8WXE0-2;Q8WXE0 Q8WXE0-2 CASKIN2 Caskin-2 1 S(0.084)HS(0.896)LS(0.018)RPGPT(0.003)EGDAEGEAEGPVGSTLGSYATLTR;S(0.14)HS(0.458)LS(0.392)RPGPT(0.011)EGDAEGEAEGPVGSTLGSYATLTR 79.73100000000001 1.2429e-06 5266200.0 7897.1 3952.5 9615.4 6247.6 8230.4 6669.1 6384.5 4917.1 9768.0 7231.799999999999 True False 7784.485905849221 3943.3482290908773 8824.858928517358 6707.069345382643 7746.304053588983 6383.878139431413 6715.05817040158 5145.566416756077 8667.824978399944 8481.806994232216 0.9177862584167281 0.46491841087311064 1.0404456190194404 0.7907594867395088 0.9132846407441966 0.7526554357783155 0.7917013644578264 0.6066592201703194 1.0219314096977474 1.0 13.050155939061643 -8.296369788913333 24.22859603508955 1.0109660283932804 0.7862798642252403 0.2583168581873384 0.15329113214237763 651.349983592819 451785.05949711654 0.1404142770040397 0.03626283905878758 5.053941505657927e-09 8.296369788913333 -0.2246861641680401 SHS(ph)METMVGGQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SHSMETMVGGQK 12 0 A0A1B0GV05;Q684P5-3;Q684P5-2;Q684P5 A0A1B0GV05 RAP1GAP2 Rap1 GTPase-activating protein 2 1 S(0.157)HS(0.837)MET(0.006)MVGGQK;S(0.439)HS(0.553)MET(0.007)MVGGQK;S(0.144)HS(0.716)MET(0.141)MVGGQK 58.268 0.035066 6569000.0 30784.7 41544.0 36968.0 40547.0 45796.0 39977.0 39704.0 46786.0 38538.0 31786.6 True False 35995.94168445971 45668.21376526888 37849.45732192074 38275.28304514765 36822.60254933674 37880.53574451359 35942.94968793282 45557.91707386459 39101.54534326693 37549.25895741285 0.9586325451931058 1.2162214390719213 1.0079947879889817 1.0193352441005088 0.9806479161439575 1.0088224587195305 0.9572212790856445 1.213284052437224 1.0413400005474045 1.0 15.196496815677413 -10.408809485572128 9.45828900024758 0.9999999883113779 1.047471363159194 0.021271222048188987 0.08964072454792739 0.0 0.0 0.08629805309446305 0.02093035224668425 3.9011308226833424e-11 10.408809485572128 0.04747137484781616 SHS(ph)PSASQSGSQLR ddPTM_PC-9_AZD4547_30min_R2 3 SHSPSASQSGSQLR 14 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.22)HS(0.775)PS(0.005)ASQSGSQLR;S(0.049)HS(0.815)PS(0.136)ASQSGSQLR;S(0.281)HS(0.697)PS(0.023)ASQSGSQLR 90.45299999999999 0.0027914000000000003 39107600.0 7030.4 11230.3 27592.8 47305.2 37003.5 27123.3 20247.8 34831.1 23307.5 24752.9 True False 9265.920958595698 14860.274854513955 27226.901443184746 36399.716998054406 31866.202751903784 25427.27576326799 22049.81497481395 29448.753834052437 24539.486866795683 23886.308505196386 0.38791766239559067 0.6221252166813952 1.139853880613726 1.5238736864733942 1.334078170554123 1.0645125745460573 0.9231152218442246 1.2328717025339415 1.027345303752449 1.0 14.543896290155999 -5.170296171831674 3.246612582189982 1.1744696398920929 0.43161598930067274 0.7118363933949923 0.16818118261210305 0.14145947533631248 2.7992210294162168 0.04847572854078282 0.16049816634628328 6.756220704525031e-06 5.170296171831674 -0.7428536505914201 down SHS(ph)PSASQSGSQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHSPSASQSGSQLR 14 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.234)HS(0.482)PS(0.284)ASQSGSQLR 73.593 0.011404000000000001 9182400.0 2899.3 2477.0 4876.5 3750.1 5169.1 4732.1 4470.8 2876.5 4369.8 3088.4 True False 3390.0942262147764 2722.9001900772946 4992.774254229239 3539.9940549882417 4156.251961694828 4483.940345614049 4047.293458211016 2800.994922903679 4433.700058150604 3648.302472239052 0.9292250990730473 0.7463471603017018 1.368519823183699 0.970312654152182 1.1392289957647168 1.2290484080565134 1.1093634612283376 0.7677529328275898 1.2152775412367425 1.0 11.833009629600422 -5.2299887824751465 24.998999662898786 1.0933649893250654 0.8377860945226963 0.29821637835150494 0.16060718263451418 841.8667523249181 669168.6200962735 0.03999841831583224 0.10580339254626736 5.8885886497468565e-06 5.2299887824751465 -0.25557889480236917 SHS(ph)PSIDGTPK ddPTM_PC-9_AZD4547_30min_R2 3 SHSPSIDGTPK 11 0 A0A0C4DH56;Q9BWT3-2;Q9BWT3 A0A0C4DH56 PAPOLG Poly(A) polymerase gamma 1 S(0.042)HS(0.94)PS(0.017)IDGTPK;S(0.024)HS(0.864)PS(0.109)IDGT(0.003)PK;S(0.001)HS(0.492)PS(0.492)IDGT(0.015)PK 95.477 0.009082600000000001 8332200.0 36520.3 47025.0 59590.0 73099.0 53991.0 60462.0 54385.0 73517.0 52186.0 54562.0 True False 48132.99573057044 62224.911626004505 58799.79766458566 56247.15491829181 46495.28160249803 56681.30158198705 59225.159642294784 62156.63690259656 54944.44542016946 52651.8009873803 0.9141756754361937 1.1818192437694335 1.116767072766968 1.0682854881217312 0.8830710579803741 1.0765311066106276 1.12484584632708 1.1805225222494173 1.0435435139880336 1.0 15.684195259919605 -6.994218787874636 24.999723779971852 1.1020453864862452 1.0409414952748788 0.06105872737623297 0.09372867864975645 427.31634892918424 1847834.413915647 0.03401036928872804 0.029911178543074488 1.0134007284318045e-07 6.994218787874636 -0.06110389121136639 SHS(ph)PSIDGTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SHSPSIDGTPK 11 0 A0A0C4DH56;Q9BWT3-2;Q9BWT3 A0A0C4DH56 PAPOLG Poly(A) polymerase gamma 1 S(0.001)HS(0.67)PS(0.32)IDGT(0.009)PK;S(0.001)HS(0.999)PSIDGTPK 122.18 0.00069485 6828100.0 37307.0 43936.0 39889.0 53027.0 54126.0 44933.0 51002.0 42365.0 45749.0 39302.0 True False 43622.33825316269 48297.67571709161 40840.10503987493 50056.06910585352 43520.39884674207 42576.634379974246 46170.72133749622 41252.963639427915 46417.99257639523 46427.1414855392 0.9395869928100112 1.0402896704750826 0.8796601240805557 1.0781639253289939 0.9373913072011444 0.9170634464591303 0.994476934400046 0.8885527370294184 0.9998029405030929 1.0 15.502680836598966 SHS(ph)PSIDGTPK ddPTM_PC-9_Lapatinib_30min_R1 1 SHSPSIDGTPK 11 0 A0A0C4DH56;Q9BWT3-2;Q9BWT3 A0A0C4DH56 PAPOLG Poly(A) polymerase gamma 1 S(0.008)HS(0.937)PS(0.054)IDGTPK 85.845 0.031715 0.0 10133.0 11380.0 13319.0 9611.8 10719.0 11872.0 8130.9 11508.0 11768.0 8496.0 True False 9988.501561835377 11353.65030918511 12223.963232826794 10318.683836024851 10088.529494364835 11364.26223498369 8551.878217200756 12042.703692019473 10442.563917466263 9964.522279791596 1.0024064657963998 1.1394073885720257 1.2267485474559503 1.0355422514285013 1.0124448730296616 1.1404723594256811 0.8582326354515025 1.2085580576644905 1.047974365880455 1.0 13.282584925542146 SHS(ph)QASLAGPGPVDPSNR ddPTM_PC-9_AZD4547_30min_R2 2 SHSQASLAGPGPVDPSNR 18 0 Q9P2M7-2;Q9P2M7;A6PVU7;A2A3M4 Q9P2M7-2 CGN Cingulin 1 S(0.066)HS(0.932)QAS(0.002)LAGPGPVDPSNR;SHS(0.999)QAS(0.001)LAGPGPVDPSNR 266.83 3.3551999999999995e-78 44447000.0 19106.0 17248.4 29169.2 49299.0 38702.0 42121.0 25174.1 38655.0 28128.2 36811.0 True False 25181.31057051225 22823.607989154214 28782.39734918331 37933.87721195735 33328.89534514788 39487.167211386906 27414.5461313063 32681.75795353282 29614.999227141587 35522.25809439639 0.7088882273079532 0.6425156849123457 0.8102637302138095 1.0678903664049832 0.9382538479558395 1.1116175978017562 0.7717568533637483 0.9200360480092435 0.8337026083320229 1.0 15.116435674020142 -5.51776314861695 5.129112559735751 0.94506290522768 0.6840907787389117 0.569300281024675 0.09572307768634869 0.1254028154476479 9.981455783527913 0.02630147006967632 0.05103623997889567 3.035546230102267e-06 5.51776314861695 -0.26097212648876833 SHS(ph)QASLAGPGPVDPSNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SHSQASLAGPGPVDPSNR 18 0 Q9P2M7-2;Q9P2M7;A6PVU7;A2A3M4 Q9P2M7-2 CGN Cingulin 1 SHS(0.999)QASLAGPGPVDPSNR;S(0.007)HS(0.933)QAS(0.06)LAGPGPVDPSNR 174.81 1.7755e-12 10794000.0 49925.4 45054.2 46796.7 65944.0 64861.0 60836.0 60640.0 59412.8 45812.5 45741.3 True False 58376.78414840246 49526.88322316528 47912.510805473066 62249.371473332656 52151.95265858435 57645.65306434276 54895.74020441887 57853.276953065106 46482.42114376505 54033.83560206843 1.0803746115363275 0.9165901822684854 0.8867131172831078 1.152044284469595 0.9651721384847971 1.0668436253327178 1.0159512015526333 1.070686104520229 0.8602465589539916 1.0 15.721575475130866 -4.420469068152621 14.68553176433756 0.9987371857682401 3.6857449163782507 0.08257593600798885 0.08556863163783522 329465.3567586906 608331.5654874748 0.02091579802399356 28652058.54455716 3.797789870869012e-05 4.420469068152621 2.6870077306100106 SHS(ph)SLPPNNSYADFER ddPTM_PC-9_Lapatinib_30min_R1 1 SHSSLPPNNSYADFER 16 0 O43293 O43293 DAPK3 Death-associated protein kinase 3 1 SHS(0.5)S(0.5)LPPNNSYADFER 125.36 0.00020575 0.0 8285.6 14495.0 12139.0 7403.2 11078.0 10106.0 9642.0 10590.0 9033.9 11906.0 True False 8167.445824607055 14461.437718070145 11140.978277895068 7947.656024351228 10426.413820185982 9673.789938236621 10141.215581331668 11082.050060695707 8016.40705081565 13963.936236252219 0.5848956688446693 1.0356275962164843 0.7978393834950077 0.569155851894974 0.7466672465259214 0.692769558279863 0.7262433320916875 0.7936193543998894 0.5740793222761932 1.0 13.769418053766106 -9.990054142705922 16.292501468060806 0.9999999975939889 0.7330768901464088 0.2783326451094743 0.13242378347074554 0.0 0.0 0.1273449411958252 0.030885684908144542 1.0231654281498322e-10 9.990054142705922 -0.2669231074475802 SHS(ph)SPASLQLGTGAGAAGSPAQQHAHLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHSSPASLQLGTGAGAAGSPAQQHAHLR 28 0 Q9GZV5;C9JR84;C9J038 Q9GZV5 WWTR1 WW domain-containing transcription regulator protein 1 1 S(0.116)HS(0.384)S(0.384)PAS(0.116)LQLGT(0.001)GAGAAGSPAQQHAHLR 54.958 0.002886 5021400.0 7133.5 7830.3 13532.0 12378.0 14218.0 12575.0 9514.5 9429.6 10725.0 8192.6 True False 8341.060656952743 8607.640435350113 13854.654200395786 11684.500790017446 11432.084964767 11915.544862977677 8613.21768098521 9182.082991487063 10881.832835293422 9677.853527414089 0.8618709338104091 0.8894162751035213 1.431583373436086 1.2073442480731087 1.181262449610729 1.2312177312071282 0.8899925646308735 0.9487726762424462 1.1244056137519407 1.0 13.240471389110068 -7.259864822911163 24.99396275919045 0.9865237717228823 1.1417132431239538 0.1526877778100746 0.16425871047087806 286.5971861217494 4549386.125162774 0.07040800914043491 0.05160948738522816 5.49711948786565e-08 7.259864822911163 0.15518947140107153 SHS(ph)SPSQIPK ddPTM_PC-9_Lapatinib_30min_R1 2 SHSSPSQIPK 10 0 Q9H792;H0YN99 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 SHS(0.544)S(0.454)PS(0.002)QIPK;S(0.001)HS(0.635)S(0.354)PS(0.01)QIPK 152.64 0.00017087 7081100.0 104715.0 99807.0 112645.0 102662.0 100199.0 98272.0 89018.0 90390.0 113075.0 71668.0 True False 103221.74489762071 99575.90302362389 103383.76292227455 110212.10595039239 94305.49181881346 94069.13564322072 93626.91647158083 94589.84938491846 100339.30276746258 84055.71830839287 1.2280157373578013 1.1846416285241756 1.2299432448244487 1.3111791579251526 1.121940228656605 1.1191283298310477 1.113867305589753 1.1253231938114765 1.1937236964572322 1.0 16.359058348856678 -6.325952918706454 11.689969097959667 1.1189533312387798 1.2339741208267456 0.5723799545304338 0.05316166297187883 0.8288594703079584 148.9914578347509 0.016122332870705438 0.01828231326950682 4.721142197710261e-07 6.325952918706454 0.1150207895879658 SHS(ph)SSEAYEPR ddPTM_PC-9_AZD4547_30min_R2 2 SHSSSEAYEPR 11 0 Q8IVF2-3;Q8IVF2 Q8IVF2-3 AHNAK2 Protein AHNAK2 1 S(0.006)HS(0.761)S(0.23)S(0.003)EAYEPR;S(0.046)HS(0.442)S(0.404)S(0.107)EAYEPR 113.52 0.00087998 23966000.0 8736.7 7245.5 25022.2 43884.0 33278.2 20233.7 12641.9 29734.0 17782.2 28145.9 True False 11514.788865350914 9587.46618152506 24690.38927878495 33767.221801041334 28658.096353545054 18968.48354039646 13767.004609394613 25139.29351934666 18722.130788919203 27160.5206079452 0.4239531720162434 0.3529927249892427 0.9090543452824071 1.2432464858999608 1.0551379617208725 0.6983843871846719 0.5068755790110807 0.9255821669336015 0.6893141357328204 1.0 14.72922351271466 -5.261571711470039 24.999740832745612 0.8754290003254835 0.3884729094148913 0.4954641412627043 0.19775788877888936 10.233068004999819 1933668.738652227 0.05707451563062423 0.13233975782531354 5.475556801382288e-06 5.261571711470039 -0.4869560909105922 SHS(ph)SSEAYEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHSSSEAYEPR 11 0 Q8IVF2-3;Q8IVF2 Q8IVF2-3 AHNAK2 Protein AHNAK2 1 S(0.279)HS(0.686)S(0.034)S(0.002)EAYEPR 109.16 0.0020956 9328300.0 1463.8 1696.0 7694.6 7304.1 8935.9 7946.8 5242.1 6961.0 8668.1 2699.6 True False 1711.5924286321479 1864.367671526479 7878.068445932999 6894.874957211701 7184.974541894877 7530.055818458129 4745.530338482591 6778.281125789159 8794.854564065918 3189.016109978158 0.5367148893593613 0.5846215908703102 2.4703758696242386 2.1620696539093136 2.2530380199126956 2.361247343623392 1.4880860349479683 2.1255085869840853 2.7578583051203696 1.0 11.638895670344732 -5.252713019247833 24.717466548551265 2.115875040111543 0.5606679203132451 0.618824408696756 0.4753425295587506 320.4667705260509 907718.1650536678 0.11550503664296571 0.29544277072271635 5.588393524580905e-06 5.252713019247833 -1.5552071197982977 SHS(ph)SSEAYEPR ddPTM_PC-9_Lapatinib_30min_R1 2 SHSSSEAYEPR 11 0 Q8IVF2-3;Q8IVF2 Q8IVF2-3 AHNAK2 Protein AHNAK2 1 S(0.061)HS(0.936)S(0.003)S(0.001)EAYEPR;S(0.002)HS(0.985)S(0.013)SEAYEPR 138.63 0.00010319 19331500.0 14936.0 12216.3 19244.5 12183.400000000001 17802.5 19329.2 15060.0 15347.400000000001 19708.7 14283.099999999999 True False 14723.00990107306 12188.013907917237 17662.291495918253 13079.407878630967 16755.39195106166 18502.53517456594 15839.733110854057 16060.496232438274 17488.89866418827 16751.914803965567 0.8788851945204367 0.7275594492058932 1.05434463478391 0.7807709167393072 1.0002075671430273 1.1045027025917038 0.9455476162703755 0.9587259976176803 1.04399400718348 1.0 14.032038389764564 -5.793546467859599 0.9137326679989 1.0071644593663633 0.8145673710331836 0.33145561572959703 0.09389873989854237 0.8461609269966919 1.3210699709122744 0.039194612045780196 0.11944511644480942 1.6086202524250108e-06 5.793546467859599 -0.1925970883331798 SHS(ph)TEPNLSSFLNDPNPMK ddPTM_PC-9_AZD4547_30min_R2 3 SHSTEPNLSSFLNDPNPMK 19 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 S(0.083)HS(0.459)T(0.459)EPNLSSFLNDPNPMK;S(0.03)HS(0.757)T(0.214)EPNLSSFLNDPNPMK;S(0.198)HS(0.593)T(0.198)EPNLS(0.009)S(0.001)FLNDPNPMK 127.96 2.3373e-05 33477500.0 70571.0 75174.0 141426.0 263473.0 173492.0 146470.0 160862.0 275943.0 210325.0 194096.0 True False 93011.11003201174 99472.52539230749 139550.59883389305 202733.37046727203 149405.63048990746 137311.20774558646 175178.40636901424 233302.34988932102 221442.35011300218 187300.75811822445 0.496586938389769 0.5310844782033414 0.7450615802943443 1.0823948205233986 0.7976776602025415 0.7331054562999445 0.9352786829535491 1.2456028060605089 1.18228218795157 1.0 17.51499721347954 -4.797425783463224 0.367909364020404 1.1178194554746494 5.2449181698639637e-17 0.6453885151664946 0.14568419941983796 4.374156419090006 0.4763349368402626 0.1499356017246741 2.1874772636232667 1.594315309803752e-05 4.797425783463224 -1.1178194554746494 SHS(ph)TEPNLSSFLNDPNPMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SHSTEPNLSSFLNDPNPMK 19 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 S(0.062)HS(0.672)T(0.266)EPNLSSFLNDPNPMK;S(0.035)HS(0.744)T(0.221)EPNLSSFLNDPNPMK;S(0.139)HS(0.641)T(0.219)EPNLSSFLNDPNPMK 107.56 0.00013876 40262700.0 83311.0 81327.0 89787.0 125207.0 179085.0 161652.0 165260.0 260477.0 176006.0 128104.0 True False 97413.90683274556 89400.60708858116 91927.86259909358 118192.05771657091 143994.57982242934 153174.68454791806 149605.37642121137 253639.75474819422 178579.75477936168 151328.24112929386 0.6437258908567883 0.5907727891464613 0.6074732773808625 0.7810310675294797 0.9515380523018259 1.0122015785344827 0.9886150483530005 1.6760900203121112 1.180082140958635 1.0 17.207321725277318 -6.645251509432852 0.9201730512167937 1.2859332155268088 0.5993059810220649 0.6581525259381016 0.1808025185506313 0.32369399622023626 0.5981094926087419 0.10420672286843226 0.10879911584051775 2.2633331822322045e-07 6.645251509432852 -0.6866272345047439 SHS(ph)TEPNLSSFLNDPNPMK ddPTM_PC-9_Lapatinib_30min_R1 2 SHSTEPNLSSFLNDPNPMK 19 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 S(0.025)HS(0.571)T(0.404)EPNLSSFLNDPNPMK;S(0.015)HS(0.715)T(0.27)EPNLSSFLNDPNPMK 135.76 5.3200000000000006e-05 22763000.0 77737.0 73997.0 103186.0 81598.0 143422.0 126100.0 150675.0 135417.0 150581.0 136403.0 True False 76628.4561247802 73825.66449286221 94702.4453894786 87598.98912294854 134986.1999385011 120706.99695345723 158476.214241563 141708.968184063 133620.9820917733 159980.07680442746 0.47898749428941084 0.4614678650461748 0.5919639950245211 0.5475618644066323 0.8437688156852124 0.7545126828574985 0.9905996884555637 0.8857913498647677 0.8352351415302942 1.0 17.287532724017296 -6.265914889292979 0.9938980899342913 0.9182560997878739 0.46614329845914537 0.8692054992004552 0.07016001236826717 0.17841058760842737 0.37234647749701927 0.03120056916728962 0.048494559410345396 5.421071192425799e-07 6.265914889292979 -0.45211280132872855 SHS(ph)VPENMVEPPLSGR ddPTM_PC-9_AZD4547_30min_R2 4 SHSVPENMVEPPLSGR 16 0 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 S(0.015)HS(0.985)VPENMVEPPLSGR;S(0.013)HS(0.987)VPENMVEPPLSGR;S(0.22)HS(0.78)VPENMVEPPLSGR;S(0.134)HS(0.866)VPENMVEPPLSGR 106.35 0.00090586 56691300.0 90069.3 87137.3 113264.0 187348.0 139151.0 120516.0 121412.0 188269.0 133647.0 148421.0 True False 118709.46384217753 115302.72816222542 111762.04535461716 144157.81309774608 119832.2855710989 112980.11546847194 132217.43279379068 159176.35204122812 140711.3075742418 143224.82596583673 0.8288330116071719 0.8050470816402211 0.7803259288391501 1.006514143938509 0.8366725863551223 0.7888305306471167 0.9231460530825037 1.1113740300804855 0.9824505397395666 1.0 17.12792205917235 -7.548834391573431 5.751252379753669 1.0338894918032357 0.8445916648427559 0.6158960110646139 0.0672463560136426 0.11797045707466501 11.842235654726277 0.032510758971275984 0.01894304201211851 2.8259573847281547e-08 7.548834391573431 -0.1892978269604798 SHS(ph)VPENMVEPPLSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SHSVPENMVEPPLSGR 16 0 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 S(0.009)HS(0.991)VPENMVEPPLSGR;S(0.208)HS(0.792)VPENMVEPPLSGR;S(0.23)HS(0.77)VPENMVEPPLSGR 93.10600000000001 0.0025204 35474300.0 73180.0 72396.6 74561.0 86781.0 116790.0 94760.0 104020.0 126052.0 94907.0 75190.0 True False 85567.92862911632 79583.6559955388 76338.81701416727 81918.94191779796 93905.83788402997 89790.6187845539 94166.47256041628 122743.2685631341 96294.8353285959 88821.35179628759 0.9633711590583194 0.8959969014890077 0.8594647060680961 0.9222888445300814 1.0572439620081857 1.0109125448854834 1.0601783316289506 1.3819117372210983 1.0841406191323095 1.0 16.438618907789397 -6.819390408597379 1.160699185805088 1.1646781536613469 0.9058047880846408 0.45695321160078983 0.10220449508843274 0.38268292500688633 1.0867104001295247 0.05442308830872295 0.04642299979366296 1.5156872293111706e-07 6.819390408597379 -0.25887336557670604 SHS(ph)VPENMVEPPLSGR ddPTM_PC-9_Lapatinib_30min_R1 4 SHSVPENMVEPPLSGR 16 0 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 S(0.002)HS(0.998)VPENMVEPPLSGR;S(0.075)HS(0.925)VPENMVEPPLSGR;S(0.212)HS(0.788)VPENMVEPPLSGR;S(0.268)HS(0.732)VPENMVEPPLSGR 130.47 1.9884e-05 23874900.0 107876.0 112203.0 116851.0 104585.0 141683.0 133527.0 148264.0 117201.0 156424.0 155053.0 True False 106337.66845796425 111943.20084723152 107243.96183790424 112276.52978533233 133349.4844994954 127816.36147663997 155940.38445867633 122646.58632328565 138805.88190225544 181853.70445486438 0.5847429326596808 0.6155673384977183 0.5897265725731857 0.6174002895453751 0.7332789007473444 0.7028526686315795 0.857504579992652 0.6744244594353381 0.7632832243827439 1.0 17.472418788980562 -14.52287874526827 0.051376297982612826 2.329718074222978 0.042310423760563695 0.8123554586117636 0.05445881843822959 225.0497803282951 0.8504939285493878 40.074425241787985 8.568233307951719 3.0000000000833556e-15 14.52287874526827 -2.2874076504624146 SHSESASPSALSSSPNNLS(ph)PTGWSQPK ddPTM_PC-9_AZD4547_30min_R2 3 SHSESASPSALSSSPNNLSPTGWSQPK 27 0 P04049;P04049-2;H7C155 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 SHSESASPSALSSSPNNLS(0.958)PT(0.039)GWS(0.002)QPK;S(0.001)HS(0.001)ES(0.002)AS(0.002)PS(0.006)ALS(0.023)S(0.092)S(0.39)PNNLS(0.434)PT(0.039)GWS(0.01)QPK;SHSESASPSALSSSPNNLS(0.982)PT(0.018)GWS(0.001)QPK 191.98 7.1292e-25 34138000.0 30952.699999999997 26788.1 116355.1 210222.8 157453.2 139082.7 76864.5 155329.5 86973.4 124629.4 True False 40795.01474384458 35446.82945515304 114812.15534892809 161759.18136988304 135593.54102006694 130385.83678239277 83705.29159373316 131326.894891819 91570.63636428477 120266.16264023687 0.3392060896287048 0.29473651338812873 0.9546505253715972 1.3450099164947003 1.1274454762947768 1.0841439846420293 0.6960003525191738 1.0919687799856816 0.7613998347831913 1.0 16.87587126609536 -5.28375995560812 5.576420019926942 1.0214450961759558 0.3121203990798453 0.7165461790398304 0.1738152308390399 0.0847389592993657 8.978061477759992 0.04780690112240485 0.10907939030828517 5.202834895373044e-06 5.28375995560812 -0.7093246970961105 down SHSESASPSALSSSPNNLS(ph)PTGWSQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SHSESASPSALSSSPNNLSPTGWSQPK 27 0 P04049;P04049-2;H7C155 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 SHSESASPSALSSSPNNLS(0.987)PT(0.013)GWSQPK;SHSESASPS(0.001)ALS(0.081)S(0.247)S(0.247)PNNLS(0.259)PT(0.14)GWS(0.024)QPK 180.21 2.4158000000000003e-18 17549000.0 19335.9 23468.3 51226.0 51726.5 67630.0 71316.0 47242.7 45894.1 62107.0 37193.5 True False 22609.085968566982 25798.077727408527 52447.42211568684 48828.43190457568 54378.38698601716 67576.06341535712 42767.529448471294 44689.42850381844 63015.197380099664 43936.38712641601 0.5145868253462663 0.587168846022341 1.1937126729328573 1.1113438108619178 1.2376617774592367 1.5380432446783534 0.9733965909718152 1.0171393559337443 1.4342371210174638 1.0 15.42312862188463 -5.244357663443264 4.921507007873865 1.1944451491825314 0.5360145200805454 0.6818426607406629 0.17427677806644815 0.10094236489791797 7.213183884463302 0.04577206292709215 0.11839120887102274 5.696949065016909e-06 5.244357663443264 -0.658430629101986 SHSESASPSALSSSPNNLS(ph)PTGWSQPK ddPTM_PC-9_Lapatinib_30min_R1 1 SHSESASPSALSSSPNNLSPTGWSQPK 27 0 P04049;P04049-2;H7C155 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 SHSESASPSALS(0.001)S(0.004)S(0.013)PNNLS(0.893)PT(0.079)GWS(0.011)QPK 111.88 8.211599999999999e-11 6891800.0 22778.0 15957.0 44244.0 19119.0 37726.0 50513.0 37522.0 38756.0 56033.0 27495.0 True False 22453.181543026374 15920.052546895166 40606.42910677894 20525.075039114337 35507.03085216975 48352.6767415542 39464.70556344395 40556.74524573396 49721.97348635173 32247.474115215402 0.6962772173350543 0.49368370651342175 1.25921270489894 0.6364862862058999 1.1010794434723303 1.4994252439368527 1.2238076514905465 1.2576719993891856 1.5418873834490898 1.0 14.976898540886397 -6.48081861585564 4.800164104188047 1.3159445388211803 0.7902813566284105 0.5388497359536346 0.23201933697461224 0.160851580755751 8.61293691622978 0.0731636542728073 0.08056634809416713 3.305075494951836e-07 6.48081861585564 -0.5256631821927699 SHSGS(ph)SSPSPSR ddPTM_PC-9_Lapatinib_30min_R1 1 SHSGSSSPSPSR 12 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SHS(0.027)GS(0.728)S(0.197)S(0.045)PS(0.002)PSR 65.374 0.023677 908930.0 2508.8 1233.4 2629.6 2269.6 2986.1 2250.9 2392.8 2373.4 2756.4 3165.8 True False 2473.0240519424265 1230.5441380798695 2413.4044385495404 2436.5139551636544 2810.463468898481 2154.6342541041795 2516.6874759396824 2483.676828522682 2445.9452058212114 3713.0043118366584 0.6660439483085683 0.33141468060164303 0.6499869743904866 0.656210914540635 0.7569243752125538 0.5802940350043325 0.6778035425158957 0.6689129933420728 0.6587509737125273 1.0 11.858371275228226 -14.52287874488419 0.13351628419819714 2.250162180837392 0.4796112037314183 0.5693462016281008 0.10159045231242526 105.60071727259157 0.8773592050709011 35.30382453467713 0.7250629896410151 3.0000000027364885e-15 14.52287874488419 -1.770550977105974 SHSGT(ph)SPDNTAPPPPPPRPQPSHSR ddPTM_PC-9_Lapatinib_30min_R1 1 SHSGTSPDNTAPPPPPPRPQPSHSR 25 1 H0YDT0;Q96D71-4;E9PMG1;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 S(0.135)HS(0.1)GT(0.382)S(0.382)PDNTAPPPPPPRPQPSHSR 81.94 2.9794e-05 10966000.0 5001.5 3899.5 5510.7 4210.2 3872.3 4240.0 3174.9 6209.3 5284.1 5056.8 True False 4930.17769283723 3890.470947334564 5057.631517917157 4519.832152815477 3644.5389272347147 4058.6650839227505 3339.2807870949914 6497.806746164105 4688.94901396019 5930.861142237542 0.8312751849349852 0.6559706683449349 0.8527651207172016 0.7620869962081552 0.6145041739857251 0.684329810896826 0.563034727505891 1.0955924595652684 0.7906017189590088 1.0 12.534025879389093 -7.762670131296964 24.999995598217307 0.9573228053317622 0.7100598801960624 0.5263261276056137 0.10992526487870083 26.316594199321393 534518.820159981 0.05515129458043787 0.02880816646778002 1.7271492514286725e-08 7.762670131296964 -0.2472629251356998 SHSGTSPDNTAPPPPPPRPQPS(ph)HSR ddPTM_PC-9_AZD4547_30min_R2 1 SHSGTSPDNTAPPPPPPRPQPSHSR 25 1 H0YDT0;Q96D71-4;E9PMG1;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 SHSGTSPDNTAPPPPPPRPQPS(0.5)HS(0.5)R 107.78 2.0061e-07 6127800.0 1373.5 1209.7 6067.0 7740.5 7191.6 4876.9 1220.7 6013.0 4281.1 5696.0 True False 1810.2444294252368 1600.7118680271715 5986.547615892619 5956.047314532871 6193.170476052024 4571.946672045127 1329.3399351907563 5083.829014993996 4507.390205961126 5496.58477372747 0.3293398544634166 0.29121935418484596 1.089139504316766 1.0835905493537616 1.1267306392969847 0.8317795249694101 0.24184834582097672 0.9249068693152227 0.8200346927251104 1.0 12.424319783228164 -5.249018278354101 24.76982641859037 0.8772480807738015 0.3102794808583508 0.4816496652847021 0.24017834114197348 640.4815915796065 1277224.729069683 0.06740004116562932 0.17554192101887792 5.636139342446544e-06 5.249018278354101 -0.5669685999154507 SHSGTSPDNTAPPPPPPRPQPS(ph)HSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SHSGTSPDNTAPPPPPPRPQPSHSR 25 1 H0YDT0;Q96D71-4;E9PMG1;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 SHSGTSPDNTAPPPPPPRPQPS(0.771)HS(0.229)R;SHSGTSPDNTAPPPPPPRPQPS(0.851)HS(0.149)R 99.603 7.210500000000001e-07 9292300.0 13193.8 12357.4 18838.3 21588.0 24444.8 23828.0 20236.5 19477.8 19072.8 17421.9 True False 15427.249750571696 13584.161004788517 19287.47651665059 20378.494349240325 19655.01691846506 22578.41773320335 18319.552220427475 18966.528388435006 19351.703617807398 20580.352558315473 0.7496105670132619 0.6600548249257202 0.9371791110963015 0.9901917030574101 0.9550379111714229 1.0970860518169578 0.8901476380697607 0.9215842311103459 0.9402999080299215 1.0 14.328980076542102 -5.316951332635642 5.57922214730299 0.9675052357890117 0.704919979019795 0.7746911133285119 0.05651790715386962 0.08470743698341542 5.834884957340604 0.015157212556762804 0.03297845410368358 4.820018080818443e-06 5.316951332635642 -0.26258525676921673 SHSLS(ph)RPGPTEGDAEGEAEGPVGSTLGSYATLTR ddPTM_PC-9_AZD4547_30min_R2 1 SHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTR 34 1 Q8WXE0-2;Q8WXE0 Q8WXE0-2 CASKIN2 Caskin-2 1 S(0.056)HS(0.232)LS(0.613)RPGPT(0.099)EGDAEGEAEGPVGSTLGSYATLTR 56.708999999999996 0.00038318 9737300.0 3618.6 1165.0 4134.0 6253.9 4422.4 3841.7 891.23 6549.0 1435.6 3827.3 True False 4769.239528444238 1541.5634671833136 4079.1804588923846 4812.159976791825 3808.426096180612 3601.477891692626 970.5477434587175 5537.0025310486735 1511.482885164512 3693.3073919394533 1.2913194116614768 0.417393762173096 1.1044790010696346 1.3029405533084624 1.0311695431830024 0.9751362422615452 0.26278553081633893 1.4991989410719067 0.409249143048121 1.0 11.850697626916187 -7.02607511452041 24.874970222412852 0.8036301552773792 1.0136514231895979 0.07718252870098519 0.3866902877869709 2204.2469103590934 2102786.869929005 0.14225149756902436 0.11060647677910929 9.417267036695267e-08 7.02607511452041 0.21002126791221865 SHSQAS(ph)LAGPGPVDPSNR ddPTM_PC-9_AZD4547_30min_R2 1 SHSQASLAGPGPVDPSNR 18 0 Q9P2M7-2;Q9P2M7;A6PVU7;A2A3M4 Q9P2M7-2 CGN Cingulin 1 S(0.001)HS(0.041)QAS(0.958)LAGPGPVDPSNR 269.34 1.8556999999999997e-78 25881000.0 4326.2 4692.6 9079.5 13406.0 11920.0 8465.3 8174.3 9965.0 7268.2 8673.4 True False 5701.841609449917 6209.391181205508 8959.09989756009 10315.453820635315 10265.113754177115 7935.963452780165 8901.796864282622 8425.138222919535 7652.382213675619 8369.74690597749 0.6812442088753946 0.7418851789617313 1.070414673012597 1.232469026425189 1.226454499698909 0.9481724527551094 1.063568225453168 1.0066180396569084 0.9142907545042318 1.0 13.030968282227214 -5.2332602362782294 4.939403523956286 1.0672590072268575 0.7018150808460689 0.6587765184322318 0.09969999691614893 0.11828945570317109 7.926561343460947 0.028320847889127216 0.07505272211516334 5.844397734335399e-06 5.2332602362782294 -0.3654439263807886 SHSS(ph)PASLQLGTGAGAAGSPAQQHAHLR ddPTM_PC-9_AZD4547_30min_R2 3 SHSSPASLQLGTGAGAAGSPAQQHAHLR 28 0 Q9GZV5;C9JR84;C9J038 Q9GZV5 WWTR1 WW domain-containing transcription regulator protein 1 1 S(0.163)HS(0.163)S(0.539)PAS(0.136)LQLGTGAGAAGSPAQQHAHLR;S(0.138)HS(0.138)S(0.422)PAS(0.303)LQLGTGAGAAGSPAQQHAHLR;S(0.092)HS(0.198)S(0.661)PAS(0.049)LQLGTGAGAAGSPAQQHAHLR 97.38799999999999 1.1045e-09 31901000.0 22953.4 34262.4 77494.8 143969.0 90557.0 72300.0 43886.2 93453.0 58096.1 72157.0 True False 30252.10373962084 45337.05076225023 76467.16831779713 110779.1713488769 77984.72367760199 67779.06957060088 47791.98678116536 79011.98618630209 61166.94124046119 69630.80539288164 0.4344643662948859 0.6511062238393273 1.0981801500979675 1.5909505961308594 1.119974460119836 0.9734063707602891 0.6863626883461431 1.134727449158293 0.8784465567407366 1.0 16.087438090150997 -5.122921107935165 3.518680941022961 1.0691661123230916 0.4728074112171587 0.48141163423870004 0.21938831785640417 0.22011230370471307 4.837364207206196 0.06287988990000644 0.21125877305787438 7.53492427490969e-06 5.122921107935165 -0.5963587011059328 SHSS(ph)PSQIPK ddPTM_PC-9_AZD4547_30min_R2 1 SHSSPSQIPK 10 0 Q9H792;H0YN99 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 S(0.259)HS(0.259)S(0.481)PSQIPK 98.105 0.00277 3263300.0 46959.0 46730.0 77932.0 107980.0 98255.0 90187.0 79514.0 92845.0 82111.0 87222.0 True False 61890.98519212207 61834.55864504399 76898.5707601357 83086.87927436968 84613.9892547544 84547.59263297051 86590.59196097116 78497.938615852 86451.21982707111 84168.38432831054 0.7353234315477369 0.7346530308084525 0.9136277400809083 0.9871506972294692 1.005294207914289 1.0045053532592574 1.0287781172466428 0.9326297426556251 1.0271222444980772 1.0 16.36099080359969 -5.388937362000751 2.336709771488226 0.9974193212939634 0.7237466480204602 0.9416759569998132 0.025834510810078783 0.06335195415299165 0.6590366979433891 0.00716700552210371 0.020303307071013934 4.083782822086382e-06 5.388937362000751 -0.2736726732735032 SHSS(ph)PSQIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHSSPSQIPK 10 0 Q9H792;H0YN99 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 SHS(0.399)S(0.464)PS(0.137)QIPK 102.05 0.0033668 3849100.0 33543.0 36892.0 41609.0 38776.0 48103.0 39406.0 39872.0 43483.0 33103.0 31095.0 True False 39221.167395551405 40554.39394926586 42601.11636301122 36603.50643348815 38677.56246027481 37339.47998970165 36095.03551171817 42341.61732404682 33587.06875027673 36732.27735211542 1.0677575751586947 1.1040533523285705 1.1597733501420873 0.9964943388237851 1.0529584672769372 1.0165304925628647 0.9826517197861527 1.1527087449046596 0.9143747998064825 1.0 15.16476072355673 -5.771028311798253 24.999064031138335 1.023000208895136 1.1098806233261038 0.3321207774315833 0.0605972905353321 228.8306803769346 596579.3153238787 0.0161731734500304 0.024337379429296938 1.6942273496163137e-06 5.771028311798253 0.08688041443096783 SHSS(ph)PSQIPK ddPTM_PC-9_Lapatinib_30min_R1 1 SHSSPSQIPK 10 0 Q9H792;H0YN99 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 SHS(0.118)S(0.813)PS(0.068)QIPK 150.09 0.00013209 6763600.0 109160.0 102110.0 110110.0 95938.0 101520.0 105940.0 85557.0 83573.0 109350.0 75161.0 True False 107603.3583825077 101873.57056861975 101057.18083689151 102993.60055978628 95548.79319599933 101409.19315820199 89986.72282638379 87456.10667823644 97033.85149345142 88152.47870426286 1.2206503998996938 1.1556517986339205 1.1463906894316813 1.1683573970201446 1.0839036474124555 1.1503839103425921 1.020807629565069 0.9921003693116488 1.1007501197894176 1.0 16.427713515902298 -6.654765807333423 0.523184145094721 1.0106627494286067 1.2025192394407582 0.6935696745104017 0.041067532231350894 0.5883714977534653 0.3437983810051619 0.03542294777697811 0.05009812516283972 2.214288439532837e-07 6.654765807333423 0.19185649001215155 SHST(ph)EPNLSSFLNDPNPMK ddPTM_PC-9_AZD4547_30min_R2 2 SHSTEPNLSSFLNDPNPMK 19 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 S(0.01)HS(0.39)T(0.599)EPNLSSFLNDPNPMK;S(0.002)HS(0.351)T(0.647)EPNLSSFLNDPNPMK 201.13 2.2954e-15 25497200.0 45284.0 42760.0 111353.0 206314.0 123709.0 119355.0 115830.0 218401.0 157903.0 143385.0 True False 59683.37003428648 56581.3337826253 109876.38646324242 158751.49481952493 106534.14072277666 111891.71298200624 126138.64560755718 184652.14380570452 166249.43021463652 138365.13479299756 0.4313468860748507 0.4089276815815944 0.7941045743035196 1.1473374058936636 0.7699493147761396 0.8086698513278137 0.9116360548216721 1.3345279797685672 1.2015268908844379 1.0 17.078120933321983 -4.990109788117059 0.528246539502197 1.1029974626223615 1.5640854298383962e-22 0.6430316633651684 0.17363776927533517 2.4969185883898337 0.6245968803736525 0.11935206015935863 1.6578665848973095 1.0230343401070858e-05 4.990109788117059 -1.1029974626223615 SHTFPELAYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SHTFPELAYR 10 0 Q9NSD9-2;Q9NSD9 Q9NSD9-2 FARSB Phenylalanine--tRNA ligase beta subunit 0 70.399 0.030112 1322100.0 8797.4 10268.0 7762.2 9466.7 13161.0 7491.6 9235.8 9773.2 10211.0 6931.2 False True 10286.626063429741 11287.339181152054 7947.280286307431 8936.311490455497 10582.196527029006 7098.727307791936 8360.918162598475 9516.66385556136 10360.316557685881 8187.771692650989 1.25634011909035 1.3785605662750844 0.9706279784816896 1.0914216744070144 1.2924391304812706 0.866991359097551 1.0211469587144075 1.1623020539401618 1.2653401861442815 1.0 12.999255159559763 -5.252853537215244 24.928574690546725 1.0873253276928956 1.3174503566589786 0.3514309145605927 0.12690106882210456 692.6009923123943 2010921.2854015592 0.03307167666086818 0.0845989546886703 5.586585666763728e-06 5.252853537215244 0.230125028966083 SHTPS(ph)PTSPK ddPTM_PC-9_AZD4547_30min_R2 2 SHTPSPTSPK 10 0 B7Z385;A0A087X0J3;A0A087WZ15;E9PDI2;P40123-2;P40123 B7Z385 CAP2 Adenylyl cyclase-associated protein;Adenylyl cyclase-associated protein 2 1 SHTPS(0.932)PT(0.065)S(0.003)PK;SHT(0.46)PS(0.521)PT(0.016)S(0.003)PK 113.38 0.0013155999999999999 8185800.0 73037.0 66923.0 90580.0 127155.0 122478.0 112931.0 79850.0 116159.0 95040.0 107185.0 True False 96261.24673602563 88554.5509994067 89378.85001607935 97841.37927516665 105474.04382417006 105869.40671753128 86956.49531005304 98209.29561827502 100063.6203719945 103432.48577457505 0.9306674398778474 0.8561580081562197 0.8641274484195927 0.9459443862579704 1.0197380739165882 1.0235604986644848 0.8407077782078016 0.9495014538499669 0.96742932960228 1.0 16.65832984872769 -5.854013500872458 5.417264036364867 0.9625202009548832 0.8812346738415883 0.33719099162962407 0.05184306593831638 0.2535400132840346 11.719102137216357 0.0156129960705631 0.02366539581769572 1.399543814407023e-06 5.854013500872458 -0.08128552711329495 SHTPS(ph)PTSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SHTPSPTSPK 10 0 B7Z385;A0A087X0J3;A0A087WZ15;E9PDI2;P40123-2;P40123 B7Z385 CAP2 Adenylyl cyclase-associated protein;Adenylyl cyclase-associated protein 2 1 SHTPS(0.981)PT(0.017)S(0.002)PK;SHT(0.024)PS(0.975)PT(0.001)SPK 129.0 0.00026087 7373600.0 84433.0 103699.0 93459.0 123051.0 124717.0 109940.0 104675.0 107560.0 104630.0 85463.0 True False 98725.83927223535 113993.55139718416 95687.41700523131 116156.85140672486 100279.59913847543 104174.55286169122 94759.42621862702 104736.66396924012 106160.01580948716 100956.76537526432 0.9779021634188017 1.1291323664487571 0.9478058914581264 1.1505603510072913 0.9932925125495868 1.0318729257466415 0.9386139291051838 1.0374407656577112 1.0515393932727732 1.0 16.62337806709037 SHTPS(ph)PTSPK ddPTM_PC-9_Lapatinib_30min_R1 1 SHTPSPTSPK 10 0 B7Z385;A0A087X0J3;A0A087WZ15;E9PDI2;P40123-2;P40123 B7Z385 CAP2 Adenylyl cyclase-associated protein;Adenylyl cyclase-associated protein 2 1 SHTPS(0.984)PT(0.012)S(0.004)PK 71.806 0.018254 7164600.0 94969.0 72966.0 83796.0 74009.0 88909.0 89288.0 74925.0 80860.0 87787.0 74736.0 True False 93614.72464481845 72797.05171001755 76906.61634191414 79451.86874678673 83679.54742181949 85469.36038049386 78804.24988915949 84617.0507939428 77899.50362190786 87654.01802053949 1.0680026627288464 0.8305044463901178 0.8773883739578604 0.9064258609134063 0.954657291377234 0.9750763548622071 0.8990375075640425 0.965352789350911 0.8887157186981901 1.0 16.419532604538183 -6.255140022897884 23.455021000246624 0.9443992815356355 0.9110612015717282 0.029690216792667368 0.06481551365454283 723.9599986884217 2695586.5378061477 0.018737468298309676 0.023544961109426568 5.557250544912483e-07 6.255140022897884 -0.03333807996390725 SHTPSPT(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 1 SHTPSPTSPK 10 0 B7Z385;A0A087X0J3;A0A087WZ15;E9PDI2;P40123-2;P40123 B7Z385 CAP2 Adenylyl cyclase-associated protein;Adenylyl cyclase-associated protein 2 1 SHTPSPT(0.899)S(0.101)PK 116.84 0.0024625 8057400.0 35671.0 37214.0 38928.0 35532.0 37752.0 38154.0 36658.0 35595.0 42295.0 32309.0 True False 35162.32499873976 37127.83326942137 35727.49010642552 38145.14181127727 35531.501583287725 36522.24236131807 38555.97187102844 37248.87364593616 37531.29171390517 37893.5676009636 0.9279233185171409 0.9797924983045735 0.9428378579354718 1.0066389687284887 0.9376657789905268 0.9638111340139255 1.0174806520473412 0.9829867179090562 0.9904396468848392 1.0 15.209665352542617 -7.159012641638021 7.700015959227873 0.9962295540981105 0.9608498832080475 0.40417920370916016 0.022537995013848604 0.3036298306594528 20.252499029199534 0.008240267499657422 0.006376949900776308 6.934056217618354e-08 7.159012641638021 -0.035379670890063 SHTPSPTS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 SHTPSPTSPK 10 0 B7Z385;A0A087X0J3;A0A087WZ15;E9PDI2;P40123-2;P40123 B7Z385 CAP2 Adenylyl cyclase-associated protein;Adenylyl cyclase-associated protein 2 1 SHTPSPT(0.017)S(0.983)PK;SHTPSPT(0.226)S(0.774)PK 129.76 0.0001335 70856000.0 150131.0 138113.0 138516.0 185843.0 171014.0 169537.0 171116.0 173361.0 145795.0 171485.0 True False 197869.53508120897 182755.3263030807 136679.18733525326 142999.76759572787 147271.65801651368 158935.8245890866 186344.99250438367 146572.04088946854 153501.42605360824 165481.36234597192 1.1957209698789106 1.1043861599410458 0.8259491304494947 0.8641442490469605 0.8899591828873924 0.9604454685162638 1.1260784287888093 0.8857314129613602 0.9276055253441942 1.0 17.3363092143384 -5.068577252921306 5.146665696208319 0.9349669832280384 1.177108765435688 0.5502036747967218 0.07963243712471071 0.14778930201858387 7.405308331364546 0.021935259865542896 0.06473129355786346 8.539309354561462e-06 5.068577252921306 0.2421417822076496 SHTPSPTS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SHTPSPTSPK 10 0 B7Z385;A0A087X0J3;A0A087WZ15;E9PDI2;P40123-2;P40123 B7Z385 CAP2 Adenylyl cyclase-associated protein;Adenylyl cyclase-associated protein 2 1 SHTPSPT(0.072)S(0.928)PK;SHTPSPT(0.119)S(0.881)PK;SHTPSPT(0.05)S(0.95)PK;SHTPSPT(0.213)S(0.787)PK 143.31 7.285399999999999e-05 69354500.0 219577.0 209382.0 186659.0 256076.0 260709.0 224930.0 268776.0 243321.0 219618.0 189319.0 True False 256747.04925656551 230168.06120256972 191109.65846819992 241728.891929593 209624.94296521563 213134.27483336523 243315.59151027168 236934.0815699098 222829.4977735639 223641.03605162085 1.1480319255778404 1.0291852750558816 0.854537529615486 1.0808789665676433 0.9373277224347591 0.9530195289569735 1.0879738164605424 1.0594392055813078 0.9963712461166133 1.0 17.770825408039578 -7.258220142461888 24.952249035291718 1.040899332751673 0.9959487444695949 0.04250110715380373 0.07933398974410222 861.6115884807523 6678394.713467384 0.03171027556045598 0.0234323542968179 5.517976639350395e-08 7.258220142461888 -0.044950588282077986 SHTPSPTS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 SHTPSPTSPK 10 0 B7Z385;A0A087X0J3;A0A087WZ15;E9PDI2;P40123-2;P40123 B7Z385 CAP2 Adenylyl cyclase-associated protein;Adenylyl cyclase-associated protein 2 1 SHTPSPT(0.005)S(0.995)PK;SHTPS(0.033)PT(0.049)S(0.918)PK;SHTPSPT(0.033)S(0.967)PK 151.7 9.4401e-05 69209000.0 209176.0 193514.0 174075.0 186059.0 209978.0 196288.0 176827.0 176879.0 177673.0 167306.0 True False 206193.11188181982 193065.93022246475 159763.22544893174 199742.39953462954 197627.5068726315 187893.21980967675 185982.23683884402 185097.44406853596 157661.5957603658 196224.6191787677 1.0508014373770829 0.9839026877997136 0.8141854274839065 1.017927313965925 1.0071493969499603 0.9575415184702143 0.9478027661218571 0.9432936847741084 0.8034751012396177 1.0 17.58214653403121 -8.016291328325966 23.225754682480904 0.8922864903377955 0.9646333951681386 0.10937580576257011 0.07409582180986729 571.3994122809703 814606.2041987078 0.04674214467719773 0.018810092796086253 9.631826959583834e-09 8.016291328325966 0.07234690483034312 SHVEDGDIAGAPAS(ph)SPEAPPAEQDPVQLK ddPTM_PC-9_AZD4547_30min_R2 3 SHVEDGDIAGAPASSPEAPPAEQDPVQLK 29 0 Q9P2E9;A0A087WVV2;Q9P2E9-3;F8W7S5;A0A087WU26 Q9P2E9 RRBP1 Ribosome-binding protein 1 1 SHVEDGDIAGAPAS(0.5)S(0.5)PEAPPAEQDPVQLK;SHVEDGDIAGAPAS(0.5)S(0.5)PEAPPAEQDPVQLK;SHVEDGDIAGAPAS(0.554)S(0.446)PEAPPAEQDPVQLK 136.42 2.2005e-13 121902000.0 238740.0 226316.0 299644.0 435809.0 389552.0 319481.0 262357.0 375640.0 316959.0 306220.0 True False 314654.35389951366 299468.22114940675 295670.5247760885 335339.96823193005 335469.42895698 299503.80256549164 285706.26474714605 317593.4693484684 333712.8056553769 295499.33100611425 1.064822559253114 1.0134311307229673 1.0005793372505831 1.1348247966929963 1.135262905045422 1.0135515418791068 0.9668592608124532 1.0747688269449822 1.129318311886371 1.0 18.172795338662787 -10.735621289611199 5.119156891292712 0.9999946774198343 1.0570451120827369 0.08658710950735227 0.05734237364530313 3.7500781382356547e-06 5.768363152155642e-07 0.05977324986477963 0.014495790043227257 1.8381405269282505e-11 10.735621289611199 0.057050434662902605 SHVEDGDIAGAPAS(ph)SPEAPPAEQDPVQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SHVEDGDIAGAPASSPEAPPAEQDPVQLK 29 0 Q9P2E9;A0A087WVV2;Q9P2E9-3;F8W7S5;A0A087WU26 Q9P2E9 RRBP1 Ribosome-binding protein 1 1 SHVEDGDIAGAPAS(0.551)S(0.449)PEAPPAEQDPVQLK;SHVEDGDIAGAPAS(0.5)S(0.5)PEAPPAEQDPVQLK;SHVEDGDIAGAPAS(0.708)S(0.292)PEAPPAEQDPVQLK;SHVEDGDIAGAPAS(0.701)S(0.299)PEAPPAEQDPVQLK 114.62 2.0998000000000003e-13 107012300.0 122950.0 126441.0 133613.0 147572.0 171437.0 156475.0 158249.0 140203.0 141606.0 129739.0 True False 143763.00662680896 138993.22686054197 136798.84065012436 139304.0192748791 137845.1505208016 148269.17554150565 143258.50909645617 136522.81980735788 143676.71985776818 153259.6536866413 0.9380355701491441 0.9069133559751554 0.8925952614366912 0.9089412374616462 0.8994223019885155 0.967437756610495 0.9347437870985031 0.8907942600894558 0.9374725598136439 1.0 17.22561842526771 -6.733695618626737 24.998031931515268 0.9385552206970043 0.9081207175671037 0.2773213499793187 0.028495973672300598 348.3670787000686 313889.2424073771 0.009395265112825825 0.00939353236810113 1.8463089773408095e-07 6.733695618626737 -0.030434503129900592 SHVEDGDIAGAPAS(ph)SPEAPPAEQDPVQLK ddPTM_PC-9_Lapatinib_30min_R1 3 SHVEDGDIAGAPASSPEAPPAEQDPVQLK 29 0 Q9P2E9;A0A087WVV2;Q9P2E9-3;F8W7S5;A0A087WU26 Q9P2E9 RRBP1 Ribosome-binding protein 1 1 SHVEDGDIAGAPAS(0.5)S(0.5)PEAPPAEQDPVQLK;SHVEDGDIAGAPAS(0.773)S(0.227)PEAPPAEQDPVQLK;SHVEDGDIAGAPAS(0.5)S(0.5)PEAPPAEQDPVQLK 144.06 3.0346e-12 105980000.0 198478.0 158870.0 202383.0 139483.0 163712.0 188184.0 159593.0 170962.0 191097.0 134021.0 True False 195647.66732359224 158502.14627594338 185743.85096097228 149741.04512164785 154082.78203017567 180135.80899832965 167855.9446454537 178905.51864746521 169573.6435193791 157186.35127824268 1.2446861049485616 1.008370923982907 1.181679258093972 0.9526338890364879 0.9802554787815309 1.1460015932265206 1.0678786248325358 1.1381746391630176 1.0788064112462863 1.0 17.262116426142327 -4.749668356760382 24.98588329738051 1.0665008128144602 1.2446865055787235 0.36084408814878244 0.07285760044183527 624.439805489464 1325390.6421631656 0.018080714945689098 0.28802670306306255 1.7796378882270163e-05 4.749668356760382 0.17818569276426333 SHVEDGDIAGAPASS(ph)PEAPPAEQDPVQLK ddPTM_PC-9_AZD4547_30min_R2 1 SHVEDGDIAGAPASSPEAPPAEQDPVQLK 29 0 Q9P2E9;A0A087WVV2;Q9P2E9-3;F8W7S5;A0A087WU26 Q9P2E9 RRBP1 Ribosome-binding protein 1 1 SHVEDGDIAGAPAS(0.451)S(0.549)PEAPPAEQDPVQLK 98.085 6.1397e-11 86204000.0 30950.0 22322.0 38850.0 47711.0 43487.0 36666.0 31629.0 44689.0 34222.0 36552.0 True False 40791.45620000807 29537.14996949864 38334.82361586093 36711.966077601945 37449.5806902601 34373.269223729556 34443.91972650809 37783.34190105878 36030.90505440232 35272.32560556292 1.156471979085346 0.8374029628724067 1.0868243859093605 1.0408150142448214 1.0617270068621107 0.9745109978886233 0.9765139988692955 1.0711894169830367 1.0215063632980232 1.0 15.106249079470214 -7.30225406626611 0.002400275806264389 0.49752648064377336 1.5415435683906147 0.005246445271363309 0.08072959113490144 652155.0261564857 962.0961880467318 208466.37118897762 209987.30548752967 4.985927207980296e-08 7.30225406626611 1.0440170877468413 SHVEDGDIAGAPASS(ph)PEAPPAEQDPVQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SHVEDGDIAGAPASSPEAPPAEQDPVQLK 29 0 Q9P2E9;A0A087WVV2;Q9P2E9-3;F8W7S5;A0A087WU26 Q9P2E9 RRBP1 Ribosome-binding protein 1 1 SHVEDGDIAGAPAS(0.258)S(0.742)PEAPPAEQDPVQLK;SHVEDGDIAGAPAS(0.207)S(0.793)PEAPPAEQDPVQLK 160.84 1.3204e-12 98245000.0 108913.0 154299.0 131045.0 148168.0 161075.0 132457.0 139598.0 123984.0 118233.0 106158.0 True False 127349.81977019616 169616.78499343406 134169.6097909301 139866.6273271376 129513.51003656216 125510.72174277817 126374.26683800238 120729.551371907 119961.93395013943 125403.60505373451 1.0155196073958777 1.352567056750518 1.0699023344140657 1.1153317902400477 1.032773419720004 1.0008541755159093 1.0077403020738673 0.9627279161565991 0.9566067410800242 1.0 16.936219297205042 -6.172057253325544 1.1206967570774764 0.9788805696096672 1.1776402271986728 0.4434148099041777 0.0819690992607007 0.41794650471185796 1.0828451205589187 0.0322434169520873 0.053069664092946715 6.728879431793271e-07 6.172057253325544 0.1987596575890056 SHVEDGDIAGAPASS(ph)PEAPPAEQDPVQLK ddPTM_PC-9_Lapatinib_30min_R1 1 SHVEDGDIAGAPASSPEAPPAEQDPVQLK 29 0 Q9P2E9;A0A087WVV2;Q9P2E9-3;F8W7S5;A0A087WU26 Q9P2E9 RRBP1 Ribosome-binding protein 1 1 SHVEDGDIAGAPAS(0.116)S(0.884)PEAPPAEQDPVQLK 146.38 3.9018999999999996e-11 93129000.0 73805.0 57860.0 74273.0 52347.0 63676.0 69372.0 57458.0 59940.0 65169.0 44309.0 True False 72752.52716582055 57726.02872490781 68166.560642071 56196.77300447295 59930.70287183274 66405.1212740304 60432.89409584684 62725.03122172813 57828.98096000674 51967.751611968684 1.3999552589661186 1.1108048151849028 1.3117088680506155 1.0813778018352882 1.1532287045882146 1.2778140137726615 1.1628922210659687 1.2069991345802604 1.1127858944485902 1.0 15.665329021614106 -14.522878745239195 0.09797583208813543 0.3684392195043752 1.3379704289504402 0.3893883493212439 0.08855715079826833 214.3230096154987 1.4296764923462506 27.781032765513302 1.5427048622082309 3.0000000002842016e-15 14.522878745239195 0.969531209446065 SHVSSEPYEPIS(ph)PPQVPVVHEK ddPTM_PC-9_AZD4547_30min_R2 6 SHVSSEPYEPISPPQVPVVHEK 22 0 O75376-2;O75376;A0A088AWL3;E7EVK1;J3KS29;J3QKP0 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 SHVSSEPYEPIS(1)PPQVPVVHEK;SHVSSEPYEPIS(1)PPQVPVVHEK;SHVSSEPY(0.001)EPIS(0.999)PPQVPVVHEK;SHVSSEPY(0.001)EPIS(0.999)PPQVPVVHEK;SHVSSEPY(0.001)EPIS(0.999)PPQVPVVHEK;SHVSSEPYEPIS(1)PPQVPVVHEK 106.72 2.9112e-05 52332100.0 37825.200000000004 41098.7 173020.0 418198.0 263111.0 195801.0 93560.6 274844.0 127330.0 193768.0 True False 49852.82678696434 54383.05104611741 170725.6417507405 321788.9121946922 226582.57927645132 183557.53251719516 101887.31214910137 232373.17508681386 134060.40385065298 186984.24129838857 0.26661512457303516 0.29084296445780794 0.9130482898732483 1.7209413475715472 1.2117736644708572 0.981673809742474 0.5448978557851305 1.2427420272064202 0.7169609744637251 1.0 17.51255716188303 -5.303288264233178 4.408128071992942 1.0675735794936467 0.26808740031134143 0.5134341504064603 0.29889432010184486 0.16039078352516709 7.121433960540657 0.08390777869737062 0.19617925529421015 4.974068201515717e-06 5.303288264233178 -0.7994861791823054 SHVSSEPYEPIS(ph)PPQVPVVHEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SHVSSEPYEPISPPQVPVVHEK 22 0 O75376-2;O75376;A0A088AWL3;E7EVK1;J3KS29;J3QKP0 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 SHVSSEPYEPIS(1)PPQVPVVHEK;SHVSSEPYEPIS(1)PPQVPVVHEK;SHVSSEPYEPIS(1)PPQVPVVHEK;SHVSSEPYEPIS(1)PPQVPVVHEK 120.56 5.0648e-07 21343200.0 41753.3 51691.3 138717.0 145589.0 176169.0 180542.0 129884.0 123784.0 141542.0 88272.0 True False 48821.309024734735 56822.870648099495 142024.53936715235 137432.12033590637 141649.94908974777 171074.0596939735 117580.447241272 120534.80115998945 143611.7839788439 104275.01483923246 0.4681975744621634 0.5449327505319178 1.3620188842564134 1.3179774709003336 1.3584265541284137 1.640604510656071 1.12759942947554 1.1559317574380186 1.3772405997760775 1.0 16.67003399197189 -5.249472408914973 8.876104990870934 1.3080010126439918 0.5046731016614435 0.782333240902903 0.16565899916108895 0.08699568353978783 53.67309506003349 0.042756749913088886 0.10567044532809118 5.630248856913147e-06 5.249472408914973 -0.8033279109825483 SHVSSEPYEPIS(ph)PPQVPVVHEK ddPTM_PC-9_Lapatinib_30min_R1 2 SHVSSEPYEPISPPQVPVVHEK 22 0 O75376-2;O75376;A0A088AWL3;E7EVK1;J3KS29;J3QKP0 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 SHVSSEPY(0.001)EPIS(0.999)PPQVPVVHEK;SHVSSEPYEPIS(1)PPQVPVVHEK 99.34299999999999 9.439e-05 14139800.0 43802.0 16906.8 82379.0 31386.0 54042.0 77119.0 35610.0 40899.0 86266.0 35052.0 True False 43177.375447696984 16867.6533433507 75606.11661213609 33694.23114062671 50863.35581065994 73820.80014316946 37453.71155893183 42799.316849140116 76549.81465874796 41110.691496145875 1.0502712038240676 0.4102984583689632 1.8390864726569767 0.8195977716352824 1.2372293911774355 1.795659412590765 0.9110455260146405 1.0410750899958117 1.8620415243057757 1.0 15.327226018288329 -5.247058619853401 24.971707220308033 1.2972076185448225 0.7302848792814601 0.25283126138424306 0.4000841240632543 1083.612196996488 1881648.968522503 0.09738512088115668 0.25516674958427066 5.661628648020335e-06 5.247058619853401 -0.5669227392633623 SHWDDS(ph)TSDSELEK ddPTM_PC-9_Lapatinib_30min_R1 2 SHWDDSTSDSELEK 14 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 SHWDDS(0.333)T(0.333)S(0.333)DS(0.001)ELEK;SHWDDS(0.331)T(0.331)S(0.331)DS(0.006)ELEK 151.3 6.1565e-05 17238800.0 65621.0 56607.0 64845.0 60131.0 61012.0 66865.0 59138.0 57544.0 68915.0 46313.0 True False 64685.2325065824 56475.92996942373 59513.69440893862 64553.234331135754 57423.3941142072 64005.33981992797 62199.87627554366 60217.70431470009 61153.06699287804 54318.140341806575 1.1908587462593352 1.0397250276618248 1.0956504408000365 1.188428652470851 1.0571678955291963 1.1783418838929862 1.1451031991180085 1.1086113025182647 1.1258313817089738 1.0 15.729146467276799 -9.909054678246164 1.451289637201705 0.9994377343917203 1.1237159943056552 0.364730309164783 0.04964209637009797 123.59206635495894 124.56160117577113 0.4945680045032861 0.013328850458705164 1.2329495934821026e-10 9.909054678246164 0.12427825991393482 SHWDDST(ph)SDSELEK ddPTM_PC-9_AZD4547_30min_R2 1 SHWDDSTSDSELEK 14 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 SHWDDS(0.245)T(0.376)S(0.376)DS(0.003)ELEK 129.17 0.00032277 0.0 10565.0 10076.0 13686.0 20164.0 12672.0 11542.0 12029.0 15871.0 12906.0 14926.0 True False 13924.450234348473 13332.869953080744 13504.514697726463 15515.5013306945 10912.711534641985 10820.276915406272 13099.557696739244 13418.501629298135 13588.184811878804 14403.445283120813 0.9667444115378654 0.9256722743068522 0.937589197048029 1.0772076420408172 0.75764591874629 0.7512283833984079 0.9094739098353382 0.9316174960599934 0.9433982317968465 1.0 13.814126323047462 -6.258154159825823 24.99387770358439 0.8736205828566957 0.9703501384793043 0.23361140762414245 0.08271679663550038 463.64880834163614 3527428.925713594 0.02641896690524716 0.03268954480389979 5.518815052729439e-07 6.258154159825823 0.09672955562260854 SICEVLDLER ddPTM_PC-9_AZD4547_30min_R2 1 SICEVLDLER 10 0 H0Y8X0;B4DFG0;H0Y993;P35659;A0A494C028;P35659-2;D6RDA2 H0Y8X0 DEK Protein DEK 0 118.71 0.003918 1321300.0 7032.0 4556.9 7402.3 11983.0 9316.3 9248.8 8000.2 8137.4 8326.4 7185.1 False True 9268.02972531363 6029.828809963636 7304.140665423099 9220.504485504474 8022.8925560436455 8670.471073922163 8712.202301559004 6879.951808849509 8766.516505317493 6933.551835974229 1.3366929309199267 0.869659440444118 1.0534486275167219 1.3298385450390027 1.157111498671929 1.250509303029373 1.25652804041305 0.9922694704831339 1.264361572929052 1.0 12.759378872729656 -4.447853507619701 22.848687353911764 1.1402128298131855 11.512011318536306 0.15790202647333906 0.14128869949049122 1199.1157223893822 363700.8875314151 0.03429769675223769 2613.346633036366 3.565713886560809e-05 4.447853507619701 10.37179848872312 SICEVLDLER ddPTM_PC-9_Lapatinib_30min_R1 1 SICEVLDLER 10 0 H0Y8X0;B4DFG0;H0Y993;P35659;A0A494C028;P35659-2;D6RDA2 H0Y8X0 DEK Protein DEK 0 132.78 0.00062265 1842300.0 8995.1 8254.4 10197.0 10324.0 10397.0 9135.7 9758.2 8603.2 9989.7 8180.7 False True 8866.828224500689 8235.28744394883 9358.642021558293 11083.2613998544 9785.46890128847 8744.987407356857 10263.431848760694 9002.936079525718 8864.55478979545 9594.723094902445 0.9241359168782601 0.8583142382008015 0.9753946965421463 1.1551413511602848 1.0198802825781774 0.9114371848837366 1.0696954719009584 0.9383216160046207 0.9238989705190216 1.0 13.228025455295807 -5.400816340597086 5.666834232855423 1.0042696815946663 0.8930847711177204 0.2805078177009611 0.07004355180744282 0.28887036061399946 12.081926255904392 0.019343647989007094 0.04103236210180515 3.973595538824963e-06 5.400816340597086 -0.1111849104769459 SIDAVIATASAPPSS(ph)SPGR ddPTM_PC-9_AZD4547_30min_R2 1 SIDAVIATASAPPSSSPGR 19 0 Q9NR48-2;Q9NR48 Q9NR48-2 ASH1L Histone-lysine N-methyltransferase ASH1L 1 SIDAVIATAS(0.007)APPS(0.116)S(0.439)S(0.439)PGR 235.72 1.4669999999999999e-43 7327000.0 22992.0 19350.0 29596.0 42229.0 31948.0 30713.0 23118.0 36182.0 25921.0 26440.0 True False 30302.977736690966 25604.509090126274 29203.537702317142 32493.756481546236 27512.571662621696 28792.511254797508 25175.45721449979 30590.903279646223 27291.131141229678 25514.343647709666 1.1876840006194382 1.003533911891349 1.14459294370046 1.2735485940851583 1.0783178294728113 1.1284833210821048 0.9867178071327618 1.1989688506994873 1.0696387693939173 1.0 14.63902090865682 SIDDLEEK ddPTM_PC-9_Lapatinib_30min_R1 2 SIDDLEEK 8 0 P09493-3;P09493-9;P09493-8;Q6ZN40;H7BYY1;P09493-2;P09493-7 P09493-3 TPM1 Tropomyosin alpha-1 chain 0 ; 122.52 0.015321000000000001 14782900.0 65210.0 55592.0 62031.0 57659.0 57167.0 51866.0 73148.0 59029.0 48376.0 60311.0 False True 64280.093441950594 55463.280139562274 56931.05062658448 61899.435204785455 53804.54945464632 49647.81208555123 76935.24552408718 61771.702835959135 42927.38545813634 70735.67599064394 0.908736539825431 0.7840920350700866 0.8048421087276332 0.8750808462334164 0.7606423307775123 0.7018779617249723 1.0876441688952438 0.8732750761317323 0.6068703643097192 1.0 16.110150410610906 SIEAVHEDIR ddPTM_PC-9_AZD4547_30min_R2 3 SIEAVHEDIR 10 0 P23919-2;P23919;H7C312;H7BZ20 P23919-2 DTYMK Thymidylate kinase 0 ;; 131.09 0.00016068 22825100.0 131900.0 117670.0 188124.0 248522.0 221880.0 182683.0 147767.0 200490.0 169843.0 171420.0 False True 173841.4563095663 155704.52633773437 185629.35284196216 191229.09252662447 191075.7919275858 171259.80313092718 160917.97673739056 169508.8773018701 178820.55423864356 165418.63797618705 1.0509181942036772 0.9412755916908766 1.122179187986571 1.156031115152532 1.1551043719456342 1.0353114088364155 0.9727922966005537 1.0247265929385287 1.081018175620487 1.0 17.335762268806654 -6.980559630720275 24.816019084867467 1.019174373863685 1.0843213665432565 0.2003464562252485 0.06287928023335569 413.5387130749284 527888.3730484468 0.024758635019149232 0.021832607834686008 1.0457800899708413e-07 6.980559630720275 0.06514699267957158 SIEAVHEDIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SIEAVHEDIR 10 0 P23919-2;P23919;H7C312;H7BZ20 P23919-2 DTYMK Thymidylate kinase 0 ;;; 152.04 0.00014111 15095100.0 136382.0 147298.0 187134.0 170236.0 198463.0 190326.0 171972.0 160337.0 161403.0 137497.0 False True 159468.77893271603 161920.77198143105 191595.98426964678 160698.22883255832 159575.59982856625 180344.9695102257 155681.56719053962 156128.32364109386 163763.21353052376 162424.11767434666 0.9818048034741 0.9969010409283873 1.1796030479524504 0.9893741836711178 0.9824624699424775 1.1103336874626561 0.9584879968544723 0.9612385517409698 1.0082444397750212 1.0 17.309406342586804 -7.302884680702113 24.9897013128964 0.9787626174219447 1.0395354477711214 0.1764446559445607 0.061313690126790554 913.4854541940252 550788.6205424815 0.0261370556788525 0.01762180436221858 4.9786926789823975e-08 7.302884680702113 0.06077283034917669 SIEAVHEDIR ddPTM_PC-9_Lapatinib_30min_R1 4 SIEAVHEDIR 10 0 P23919-2;P23919;H7C312;H7BZ20 P23919-2 DTYMK Thymidylate kinase 0 ;;; 131.09 9.203e-05 18430300.0 304808.0 261645.0 315683.0 253540.0 294606.0 297013.0 235349.0 261776.0 315133.0 222377.0 False True 300461.38202505896 261039.17707792096 289728.7623116193 272186.1773846455 277277.85429768125 284310.4463611199 247534.21964849895 273939.0686202714 279639.4030423947 260814.56815127275 1.1520115005646119 1.0008611824417644 1.1108611162532005 1.0436003606469453 1.063122571193415 1.090086525367017 0.949081262611561 1.0503211939502797 1.0721770836060183 1.0 17.992664929943714 SIFAS(ph)PESVTGK ddPTM_PC-9_AZD4547_30min_R2 2 SIFASPESVTGK 12 0 O75940 O75940 SMNDC1 Survival of motor neuron-related-splicing factor 30 1 SIFAS(0.996)PES(0.004)VTGK;S(0.005)IFAS(0.95)PES(0.044)VT(0.001)GK 126.32 0.00026707 6379200.0 75555.0 62000.0 74964.0 113914.0 104286.0 88115.0 67111.0 91952.0 84377.0 83152.0 True False 99579.91835837181 82040.28752391879 73969.92837939247 87652.8872537558 89807.68900739223 82605.15512051829 73083.74898876622 77742.9312467535 88836.9959609405 80240.87378949912 1.241012387522175 1.0224251512906026 0.9218484905017658 1.0923720432519353 1.119226209362953 1.0294648004110913 0.9108045007148273 0.968869449885371 1.1071289701305114 1.0 16.29204969592967 -6.999754616992814 24.99563415258092 0.9906819645698659 1.0687994835791983 0.1597613931325671 0.0877518680747259 17.917508456026628 1824853.2423302515 0.03226293225655947 0.02817295540339992 1.0005651749056055e-07 6.999754616992814 0.07811751900933239 SIFAS(ph)PESVTGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SIFASPESVTGK 12 0 O75940 O75940 SMNDC1 Survival of motor neuron-related-splicing factor 30 1 SIFAS(0.577)PES(0.412)VT(0.01)GK;S(0.05)IFAS(0.788)PES(0.162)VT(0.001)GK 106.54 0.0016587 15528100.0 141209.0 143076.0 145005.0 158850.0 166125.0 127953.0 140778.0 123909.0 117945.0 94498.0 True False 165112.89469512022 157279.6397236569 148462.46913452502 149950.14949864827 133573.9987882905 121242.91943161699 127442.48869554236 120656.52004243793 119669.72249498195 111629.73935424339 1.4791120686142119 1.4089403113676466 1.3299544547300022 1.3432813725632713 1.1965807638805792 1.0861166579173616 1.1416535542658497 1.0808635829521123 1.0720236666971394 1.0 16.76836190217047 -5.8964103225126125 0.4604064862622973 1.0224439575410302 1.573136440379561 0.9542197888827544 0.033423146419677835 0.39024976236173003 0.13065151063812325 0.02939675380933434 0.10632259492267551 1.269374230527966e-06 5.8964103225126125 0.5506924828385307 SIFAS(ph)PESVTGK ddPTM_PC-9_Lapatinib_30min_R1 2 SIFASPESVTGK 12 0 O75940 O75940 SMNDC1 Survival of motor neuron-related-splicing factor 30 1 SIFAS(0.893)PES(0.104)VT(0.002)GK;S(0.016)IFAS(0.824)PES(0.157)VT(0.003)GK 133.04 6.9446e-05 11985600.0 124862.0 131687.0 137437.0 124338.0 105835.0 101948.0 105540.0 95455.0 98169.0 77379.0 True False 123081.44498311362 131382.0868423253 126137.46038216198 133482.23129940854 99609.99337961576 97587.9216923954 111004.344788814 99890.1877756101 87112.17345460124 90753.85704896334 1.3562117246070209 1.4476749651691643 1.3898853942274711 1.4708160693092358 1.0975841316129888 1.0753032969138154 1.2231363866874017 1.100671541945788 0.959872960634639 1.0 16.469671338659637 -6.268454460290812 24.24572321252652 1.088440783823457 1.4165232057456272 0.8439012908593866 0.07152995912714498 140.53824718307908 485731.4429412614 0.022356472505720516 0.025921148780326933 5.389463558162639e-07 6.268454460290812 0.3280824219221701 SIFNSAMQEMEVY(ph)VENIRRK ddPTM_PC-9_AZD4547_30min_R2 2 SIFNSAMQEMEVYVENIRRK 20 2 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;A0A087WYS3;Q9ULU4-18;Q9ULU4-8;Q9ULU4-15;Q9ULU4-17;A0A087WV57 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 S(0.002)IFNS(0.002)AMQEMEVY(0.996)VENIRRK;S(0.03)IFNS(0.03)AMQEMEVY(0.941)VENIRRK 45.70399999999999 0.019609 97411700.0 118013.0 91386.0 62728.0 62565.0 72057.0 75932.0 80025.0 63407.0 73736.0 67468.0 True False 155538.67917711014 120924.73734936854 61896.18573425292 48141.605869614235 62053.12934435746 71183.96003644333 87147.06997103323 53608.905097908566 77633.53442497243 65105.965855660885 2.3890080906247126 1.8573526367377329 0.9506991397912135 0.7394346314797569 0.9531097270245322 1.0933554106893566 1.3385420034200428 0.8234100269207102 1.1924181356449732 1.0 15.990502127487611 -5.081646186689837 2.8922850736798815 1.0065142288266686 2.3524015433068373 0.8817749603091738 0.16781808454574768 0.08918684388026994 1.3728125633237376 0.04728022068762029 0.198387086205249 8.286169508162433e-06 5.081646186689837 1.3458873144801686 up SIGAAS(ph)PRPQSLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SIGAASPRPQSLEK 14 1 Q96L73-2;Q96L73-3;Q96L73 Q96L73-2 NSD1 Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific 1 S(0.035)IGAAS(0.964)PRPQS(0.002)LEK 57.196999999999996 0.032102 4033200.0 30568.0 28219.0 30919.0 35580.0 36890.0 28396.0 37610.0 38633.0 32541.0 25790.0 True False 35742.55865447978 31020.395827126013 31656.226220960467 33586.56795191635 29661.669317080785 26906.863771698925 34047.30852717999 37618.924685047044 33016.8505634763 30465.522846472315 1.17321336760247 1.018213144853936 1.0390836349826842 1.1024451515627092 0.9736143202451354 0.8831906121320529 1.1175684953367677 1.234803186363271 1.0837447540244467 1.0 14.894889879515373 -7.489677997065992 24.821202662448332 1.1308016248519737 1.0293081620079723 0.13504024517231272 0.08992678580990278 896.2815966527679 670070.9308989351 0.038001577292504786 0.025599342809163154 3.2383367090431144e-08 7.489677997065992 -0.1014934628440014 SIGS(ph)PESTPK ddPTM_PC-9_AZD4547_30min_R2 3 SIGSPESTPK 10 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 SIGS(0.97)PES(0.014)T(0.015)PK;SIGS(0.989)PES(0.005)T(0.005)PK;S(0.011)IGS(0.923)PES(0.014)T(0.053)PK 140.78 0.00011448 88085000.0 552941.0 594250.0 819562.0 1069723.0 1023709.0 952800.0 837077.0 861681.0 827165.0 883117.0 True False 728764.7361127208 786329.6913078822 808694.0723877022 823114.8894055997 881584.6758536 893221.2653785401 911575.2313669806 728528.0009095363 870887.2532091845 852199.3426298957 0.8551575900818529 0.9227062871009275 0.9489494205570075 0.9658713029107239 1.0344817600222747 1.0481365341377176 1.0696737086816452 0.8548797968574954 1.0219290366050011 1.0 19.7008314130863 -5.079859399540833 1.1072677498008856 1.000883656255912 0.8315208030173776 0.4114474830261562 0.055790604545665125 1.1817426351113351 1.691171301180112 0.01918762025999839 0.2079184598788391 8.320330936601182e-06 5.079859399540833 -0.1693628532385344 SIGS(ph)PESTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SIGSPESTPK 10 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 SIGS(0.994)PES(0.003)T(0.003)PK;S(0.001)IGS(0.991)PES(0.003)T(0.005)PK;SIGS(1)PESTPK;SIGS(0.945)PES(0.027)T(0.027)PK 159.94 0.00011546 73194200.0 561159.0 657212.0 644591.0 844440.0 938100.0 851780.0 908120.0 850350.0 743300.0 682534.0 True False 656152.1353045432 722455.6639972052 659960.4940649819 797128.7645114202 754286.0392071953 807111.1573270088 822096.2993805564 828029.2135202993 754169.3563145553 806272.011263827 0.8138098881493211 0.8960445778897371 0.8185333049456813 0.9886598485068645 0.9355230352407446 1.0010407729047501 1.019626488202071 1.0269849405070728 0.935378316224073 1.0 19.620907116040158 -5.768667974745495 24.999942900966012 0.987700663364076 0.8481207835250807 0.7736824849959185 0.035640076747864714 73.99318638459502 255904.6509329219 0.010033483872767713 0.015232393448144551 1.703460334062737e-06 5.768667974745495 -0.13957987983899534 SIGS(ph)PESTPK ddPTM_PC-9_Lapatinib_30min_R1 1 SIGSPESTPK 10 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 SIGS(0.69)PES(0.187)T(0.124)PK 110.93 0.0016683 3027900.0 49113.0 52235.0 58323.0 60464.0 66181.0 52621.0 53075.0 59343.0 60198.0 47179.0 True False 48412.63961377888 52114.05306680881 53527.90807329057 64910.72426199112 62288.36369685223 50370.52249554221 55822.96380203054 62100.29242227245 53417.86732695741 55333.82728793411 0.874919411626088 0.9418118286961981 0.9673631971046158 1.1730749063176642 1.1256832709714732 0.9103025213389825 1.0088397376084466 1.1222844228563567 0.9653745266705148 1.0 15.755874094010847 -5.531970655614763 24.792233355279492 1.0470856332308447 0.9199210593350337 0.3363595037922936 0.07699105639970724 201.36921082243205 549101.0311149715 0.02187823742891477 0.037961237636098974 2.9378481496147004e-06 5.531970655614763 -0.12716457389581104 SIGVSNFNHR ddPTM_PC-9_AZD4547_30min_R2 2 SIGVSNFNHR 10 0 B4DK69;P52895;S4R3P0 B4DK69 AKR1C2 Aldo-keto reductase family 1 member C2 0 ; 129.89 0.00019415 12668400.0 46410.0 47443.0 74770.0 172270.0 130870.0 101062.0 68860.0 132683.0 81157.0 99320.0 False True 61167.414612031534 62778.02195156902 73778.50094614993 132555.81304496826 112700.95948063416 94742.57716381818 74988.40660050417 112179.89110202016 85446.79333470082 95842.83703065502 0.6382053840128641 0.6550100549662327 0.769786279621002 1.383053936545834 1.1758933997810095 0.9885201659203292 0.7824101302063854 1.1704567036777072 0.8915303008754941 1.0 16.548382993325966 -5.540232016862494 24.652128214131867 1.0556044971657847 0.6630552597389319 0.5461223382281215 0.15643321196564564 149.1405609767382 211868.77288274872 0.04461892083105711 0.07730434480534852 2.8824911537573643e-06 5.540232016862494 -0.3925492374268529 SIGVSNFNHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SIGVSNFNHR 10 0 B4DK69;P52895;S4R3P0 B4DK69 AKR1C2 Aldo-keto reductase family 1 member C2 0 70.41199999999999 0.030083 5149000.0 24684.0 22947.0 32182.0 39509.0 55651.0 41777.0 34664.0 31335.0 36248.0 30596.0 False True 28862.51366877712 25225.02650856023 32949.34093091464 37295.43881990622 44746.58604404613 39586.14057579472 31380.37497437296 30512.48945217689 36778.05842552131 36142.812602197286 0.7985685559795763 0.6979264947141022 0.9116429674018092 1.0318908832689702 1.2380493609212302 1.095270061339612 0.8682327886254543 0.8442201161268201 1.0175759930560968 1.0 15.14142115939207 -5.468803679146328 3.6308104549770674 1.0126642275081208 0.750593780371391 0.4939559235573896 0.10638845948767352 0.21882242097270455 5.74790778109754 0.03330267686812544 0.07220545971463146 3.3977883336236795e-06 5.468803679146328 -0.2620704471367298 SIGVSNFNHR ddPTM_PC-9_Lapatinib_30min_R1 2 SIGVSNFNHR 10 0 B4DK69;P52895;S4R3P0 B4DK69 AKR1C2 Aldo-keto reductase family 1 member C2 0 ; 185.96 0.0012478 50131000.0 254890.0 326870.0 323270.0 393400.0 391940.0 461510.0 362950.0 291940.0 346420.0 283890.0 False True 251255.2218588988 326113.15259783267 296691.98845828715 422331.94834392914 368886.859783688 441772.2931323551 381741.7750720104 305504.59817936854 307402.53163567884 332960.0082403523 0.7546108110302734 0.9794364023514285 0.8910739461662779 1.268416440088091 1.1079014015322863 1.3268028658067996 1.1465093873869807 0.9175414182439452 0.9232416026785282 1.0 18.344989380327632 -5.683976228396951 11.231741359050773 1.1070247431625075 0.884779853845899 0.3628817618279525 0.13526879444177534 0.598233315567143 83.52029720775836 0.0394963048417667 0.06842084854780381 2.0702546634364573e-06 5.683976228396951 -0.22224488931660857 SIKY(ph)DEQIRFPWMLNMEPYTVSGMAR ddPTM_PC-9_Lapatinib_30min_R1 1 SIKYDEQIRFPWMLNMEPYTVSGMAR 26 2 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 S(0.202)IKY(0.797)DEQIRFPWMLNMEPYTVSGMAR 43.841 0.012391 38423000.0 33034.0 22989.0 82180.0 32581.0 72693.0 75126.0 53843.0 73349.0 94568.0 57814.0 True False 32562.929102306323 22935.770382939954 75423.47762397377 34977.11542702988 68417.34065993676 71913.03610725958 56630.72708417768 76757.06231368938 83916.75599481219 67807.07286768738 0.48022909300106037 0.3382504127216161 1.112324635678469 0.5158328467486138 1.0090000610030785 1.0605536128595936 0.8351743363805392 1.131991974693646 1.2375811614602477 1.0 16.049148146405706 -4.97284796216481 0.46994483561807 1.101286315186125 1.5868092161214166e-18 0.5488882288060156 0.20107894174892216 3.0914181426295504 0.6038950327245521 0.13898259832083223 1.8596659392303216 1.0645156186845968e-05 4.97284796216481 -1.101286315186125 SILAKPSS(ph)SPDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SILAKPSSSPDPR 13 1 Q9BTC0;Q9BTC0-1 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 SILAKPS(0.134)S(0.433)S(0.433)PDPR 57.567 0.032494999999999996 5963300.0 218650.0 179160.0 209530.0 266210.0 258860.0 244400.0 255920.0 228100.0 205060.0 189930.0 True False 255663.12646565 196945.82077280892 214525.9898469502 251295.11676446474 208138.24124205866 231583.23375838913 231677.40489965217 222112.6166919279 208058.61456459368 224362.80551494687 1.139507619718269 0.8778006689691199 0.9561566559777157 1.1200391089231752 0.9276860340748087 1.0321819306318187 1.032601657694185 0.9899707582196859 0.9273311326584075 1.0 17.775474002670748 -8.009495709706364 22.86170405735388 0.9619940038195204 1.0069413563527034 0.05660263622276873 0.07735905434817686 463.63652866447273 1116224.5795163237 0.044575672685130775 0.019438433372879954 9.78372619851195e-09 8.009495709706364 0.04494735253318305 SILAKPSSS(ph)PDPR ddPTM_PC-9_AZD4547_30min_R2 1 SILAKPSSSPDPR 13 1 Q9BTC0;Q9BTC0-1 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 SILAKPS(0.092)S(0.107)S(0.801)PDPR 87.719 0.0032836 13365000.0 89538.0 72447.0 104970.0 149530.0 129260.0 108300.0 98427.0 119100.0 100430.0 107880.0 True False 118009.22149390404 95864.07597169919 103578.02921382053 115058.16871547051 111314.48019001144 101527.9838796134 107186.8123216354 100695.8316457318 105738.52476809142 104103.15403611652 1.1335796939731824 0.920856595165609 0.9949557261049572 1.1052323032936482 1.0692709670582419 0.975263283996086 1.0296211802040989 0.9672697487224775 1.015709137221794 1.0 16.667654253384732 -6.768787067350302 24.95275350350795 0.9975300640996533 1.0384850274579103 0.14018465551056258 0.05740656479156583 415.69275166562 1411681.9906351129 0.020537278175524053 0.018465862510113198 1.7029932737526572e-07 6.768787067350302 0.04095496335825699 SILAKPSSS(ph)PDPR ddPTM_PC-9_Lapatinib_30min_R1 1 SILAKPSSSPDPR 13 1 Q9BTC0;Q9BTC0-1 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 SILAKPS(0.006)S(0.117)S(0.877)PDPR 88.10799999999999 0.0031927 10430000.0 170020.0 142520.0 174960.0 122680.0 138050.0 134070.0 129050.0 132340.0 137430.0 122750.0 True False 167595.4836221502 142190.00369640297 160575.46416513098 131702.2964484829 129930.17041674264 128336.1386324348 135731.5775535003 138488.9995309229 121951.18619794275 143967.17394590628 1.1641228971065443 0.9876557259492288 1.1153616464366038 0.914807819301699 0.9024985825280014 0.891426393357248 0.9427953180806314 0.9619484479354876 0.8470763359136595 1.0 17.135380373714774 -5.768362280858069 24.999999999812697 0.9200136220144922 1.0789076605580668 0.6423064239146213 0.05662487670841572 94.08307618622084 339754.36032082787 0.014933262025100397 0.02270684318037107 1.704659798357692e-06 5.768362280858069 0.15889403854357453 SILFVPTSAPR ddPTM_PC-9_Lapatinib_30min_R1 2 SILFVPTSAPR 11 0 P14625 P14625 HSP90B1 Endoplasmin 0 ; 140.17 0.00054597 10538400.0 50287.0 34809.0 45961.0 39562.0 37051.0 34337.0 38186.0 32435.0 48293.0 39784.0 False True 49569.89815849362 34728.40189915858 42182.26399459059 42471.52145496317 34871.733025068694 32868.48655345645 40163.08423446702 33942.04850978897 42853.733792165076 46660.61139115222 1.0623499495742368 0.7442766149811697 0.90402295934316 0.9102221378740146 0.7473483948322432 0.7044161140093628 0.860749206601325 0.7274239984824772 0.9184134651156971 1.0 15.509917590540756 -4.749098538357741 24.998131347417164 0.8251500494842929 1.062350496237843 0.33414169957285655 0.09524534666394718 648.548143904449 1313647.2410729614 0.022895878306154416 0.388487580769341 1.781974404140398e-05 4.749098538357741 0.23720044675355 SILKPS(ph)TPIPPQEGEEVGESSEEQDNAPK ddPTM_PC-9_AZD4547_30min_R2 1 SILKPSTPIPPQEGEEVGESSEEQDNAPK 29 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(0.015)ILKPS(0.492)T(0.492)PIPPQEGEEVGESSEEQDNAPK 70.217 4.6043e-05 4000300.0 10318.0 8046.8 10012.0 14570.0 11994.0 11358.0 12950.0 13206.0 13658.0 12774.0 True False 13598.909372267637 10647.770736249508 9879.234338275412 11211.111604256037 10328.840131510093 10647.782464493543 14102.524912525829 11165.316143690454 14379.933996640375 12326.786148103001 1.1031999102507677 0.8637913084821479 0.8014444494760502 0.9094918553431173 0.8379183355184289 0.8637922599259301 1.144055290899656 0.9057767377110465 1.166559865959331 1.0 13.589509087435216 -7.243857678855875 24.738440742938657 1.0462460392744872 0.8887072780900809 0.36207416554070815 0.10187608555668787 776.719278705606 1092888.909175419 0.0377379565962197 0.02916204802214178 5.703511494631964e-08 7.243857678855875 -0.15753876118440635 SILKPS(ph)TPIPPQEGEEVGESSEEQDNAPK ddPTM_PC-9_Lapatinib_30min_R1 1 SILKPSTPIPPQEGEEVGESSEEQDNAPK 29 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(0.005)ILKPS(0.566)T(0.429)PIPPQEGEEVGESSEEQDNAPK 79.884 1.2305e-06 4268900.0 36982.0 25616.0 23714.0 25406.0 25410.0 25191.0 21148.0 19281.0 26660.0 29113.0 True False 36454.62989833178 25556.687725842345 21764.326458687196 27274.441991931526 23915.43375798213 24113.639653089147 22242.93996204129 20176.865648751078 23657.270057754155 34145.14325936594 1.0676373392673453 0.7484721189105628 0.6374062130407752 0.7987795448610456 0.7004051374545683 0.7062099423605384 0.6514232432145411 0.5909146579203942 0.6928443637812243 1.0 15.059392766441954 -4.767470819270704 4.201998954330681 0.7056305474294443 1.1012535728488173 0.4717689538027058 0.10785912493304027 0.1745260093778116 6.17707816271459 0.025291782885928968 0.21201363432828077 1.7081624895415467e-05 4.767470819270704 0.395623025419373 SILKPSTPIPPQEGEEVGES(ph)SEEQDNAPK ddPTM_PC-9_AZD4547_30min_R2 1 SILKPSTPIPPQEGEEVGESSEEQDNAPK 29 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 SILKPSTPIPPQEGEEVGES(0.5)S(0.5)EEQDNAPK 120.26 7.9504e-14 19535000.0 116710.0 124720.0 134010.0 155880.0 160270.0 158250.0 146190.0 164760.0 143100.0 162570.0 True False 153821.35228119374 165033.3009674704 132232.93983942145 119944.27432199262 138019.2769615744 148354.60248336865 159200.6267924443 139300.12780815092 150663.97385556006 156878.47378245686 0.9805128044176257 1.0519818110693875 0.8429004735397201 0.7645680852831291 0.8797846743012397 0.9456657685814291 1.014802241212568 0.8879492797802088 0.9603865350225523 1.0 17.259287879656313 -6.896676670474012 6.067675111571306 0.9596046767821202 0.9013337264925576 0.1212482165708777 0.07834795529568318 0.5669661240208795 28.837473673295783 0.031332061494614934 0.027613228654162075 1.26859597614342e-07 6.896676670474012 -0.05827095028956264 SILKPSTPIPPQEGEEVGES(ph)SEEQDNAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SILKPSTPIPPQEGEEVGESSEEQDNAPK 29 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 SILKPSTPIPPQEGEEVGES(0.5)S(0.5)EEQDNAPK;SILKPSTPIPPQEGEEVGES(0.5)S(0.5)EEQDNAPK;SILKPSTPIPPQEGEEVGES(0.5)S(0.5)EEQDNAPK 103.14 2.0137e-11 29981000.0 160407.0 165891.0 143137.0 198116.0 187812.0 169218.0 185007.0 175560.0 157949.0 126696.0 True False 187560.73691733676 182359.5621445753 146549.92893009528 187016.20282073843 151011.58681972296 160343.91018873593 167481.7976253118 170951.73602119624 160258.70531484953 149664.98187501577 1.253203886223482 1.218451770480703 0.979186494356296 1.249565532817252 1.0089974617164068 1.0713522173318943 1.1190446524436473 1.1422293570579982 1.070782913324912 1.0 17.19137717823058 -5.0896305882399115 7.690329818575675 1.0899309398469779 1.244767679787889 0.4043141862647919 0.07534396931940476 0.241508662011817 18.14077612834383 0.01801443384099685 0.04848907683189739 8.135222055710241e-06 5.0896305882399115 0.15483673994091118 SILKPSTPIPPQEGEEVGES(ph)SEEQDNAPK ddPTM_PC-9_Lapatinib_30min_R1 3 SILKPSTPIPPQEGEEVGESSEEQDNAPK 29 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 SILKPSTPIPPQEGEEVGES(0.5)S(0.5)EEQDNAPK;SILKPSTPIPPQEGEEVGES(0.5)S(0.5)EEQDNAPK;SILKPSTPIPPQEGEEVGES(0.5)S(0.5)EEQDNAPK 104.38 1.5247e-11 50713000.0 260113.0 218006.0 188287.0 204734.0 210203.0 197337.0 184382.0 196364.0 203700.0 154067.0 True False 256403.74092111763 217501.22050124846 172806.7696688383 219790.8213326027 197839.2728149986 188897.35652501485 193928.39777194505 205487.78830202617 180757.16094390556 180697.27566862656 1.4189684928694004 1.2036773642349494 0.9563330107186655 1.21634828482787 1.0948658306161076 1.0453802129890772 1.073222587636476 1.1371936159063178 1.0003314121646683 1.0 17.463215229621113 -4.880293452645323 3.262694197232859 1.0760342532760716 1.4335166116519613 0.6939675470905999 0.07203742564303733 0.1505796920512881 2.7111553098040893 0.017557514682507797 0.11942447195753988 1.3173662937617929e-05 4.880293452645323 0.3574823583758897 SILKPSTPIPPQEGEEVGESS(ph)EEQDNAPK ddPTM_PC-9_AZD4547_30min_R2 2 SILKPSTPIPPQEGEEVGESSEEQDNAPK 29 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 SILKPSTPIPPQEGEEVGES(0.425)S(0.575)EEQDNAPK;SILKPSTPIPPQEGEEVGES(0.422)S(0.578)EEQDNAPK 97.59299999999999 5.4135e-11 32638900.0 143146.0 126743.0 148861.0 169776.0 158931.0 174941.0 155047.0 160617.0 152827.0 160705.0 True False 188663.45037823432 167710.19615554909 146887.00587595042 130636.76621305237 136866.17399875209 164001.9116148056 168845.88263416162 135797.33326148195 160905.12321749586 155078.76686479533 1.216565324785692 1.0814517006171864 0.9471767724592055 0.8423897665303685 0.8825590812059926 1.0575394358003238 1.0887749886570164 0.8756668369685723 1.0375703035979142 1.0 17.24264164284903 -4.954114396008137 2.693011508394372 0.9627482902843995 1.2249728099495543 0.5030270868399835 0.07816271082151281 0.2879436039139042 3.6120618961006854 0.022058558919017174 0.14357221669177153 1.1114389284347852e-05 4.954114396008137 0.2622245196651548 SILKPSTPIPPQEGEEVGESS(ph)EEQDNAPK ddPTM_PC-9_Lapatinib_30min_R1 1 SILKPSTPIPPQEGEEVGESSEEQDNAPK 29 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 SILKPSTPIPPQEGEEVGES(0.421)S(0.579)EEQDNAPK 101.39 3.0879e-11 11842000.0 67281.0 64759.0 61608.0 60055.0 61926.0 57582.0 51741.0 51669.0 53858.0 53448.0 True False 66321.56060217583 64609.054514281066 56542.82805375725 64471.64503760712 58283.63443120035 55119.352090198045 54419.89580934265 54069.73036695813 47791.94489011712 62686.41558501663 1.0579893583519564 1.0306707427968491 0.901994914305998 1.0284787291780837 0.9297649879526907 0.8792870285499739 0.868129008517599 0.8625430224771368 0.7623971548556749 1.0 15.935865218246938 -6.265795742830558 0.8070178205973587 0.8565140231770251 1.0305737541079198 0.45134333463316834 0.06662062443822168 0.5919712095095055 0.8308265736654209 0.035706754971512794 0.060580260660753366 5.422558639515294e-07 6.265795742830558 0.17405973093089477 SILPYPVS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 SILPYPVSPK 10 0 Q8IWI9-3;Q8IWI9;H3BP52;H3BTF4 Q8IWI9-3 MGA MAX gene-associated protein 1 SILPYPVS(1)PK;SILPYPVS(1)PK;SILPYPVS(1)PK 122.64 0.00052199 274378000.0 501638.0 478780.0 451846.0 581240.0 551262.0 518551.0 498985.0 459269.0 460204.0 515332.0 True False 661148.4492814115 633536.2719468042 445854.2268090681 447244.0980684823 474728.7867747635 486125.92399591405 543393.6983379702 388299.5290017081 484529.44391491316 497290.383534852 1.329501778381113 1.2739765193999646 0.8965671598952626 0.8993620485668163 0.9546309409811716 0.977549415977887 1.0927090414968523 0.7808305606908937 0.9743390581389666 1.0 18.923729007405917 -5.226144291457349 6.369472823478916 0.9439553438473484 1.3068434005910765 0.7715054810419304 0.07723852525298486 0.08919720273358571 11.222845992138861 0.01983364965861275 0.052167445002306835 5.940947417897536e-06 5.226144291457349 0.36288805674372815 SILPYPVS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SILPYPVSPK 10 0 Q8IWI9-3;Q8IWI9;H3BP52;H3BTF4 Q8IWI9-3 MGA MAX gene-associated protein 1 SILPYPVS(1)PK;SILPYPVS(1)PK;SILPYPVS(1)PK 128.28 0.00021322 84102000.0 430072.0 419040.0 369826.0 487594.0 459923.0 436990.0 547347.0 488856.0 407820.0 414183.0 True False 502874.6952908088 460639.5218611185 378644.0544129157 460275.6889810765 369804.3897348804 414073.47512307065 495498.3297108852 476024.0479857479 413783.5959803607 489271.09922917635 1.0278038005577363 0.9414811596001367 0.7738941764789534 0.9407375373411985 0.7558271688589207 0.8463068343407653 1.012727566560787 0.972924925947397 0.8457143629212053 1.0 18.90027454112323 -7.248852880151842 24.874392445486965 0.9555854603421206 0.8759132754866338 0.15742601870745698 0.08653748671581374 1400.300741124478 2767384.775082277 0.03418962659037141 0.026304087739324498 5.63828623790303e-08 7.248852880151842 -0.07967218485548677 SILPYPVS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 SILPYPVSPK 10 0 Q8IWI9-3;Q8IWI9;H3BP52;H3BTF4 Q8IWI9-3 MGA MAX gene-associated protein 1 SILPYPVS(1)PK;SILPYPVS(1)PK 107.99 0.0020919 73384000.0 583820.0 455280.0 410140.0 428980.0 464400.0 441060.0 463490.0 436670.0 421190.0 404290.0 True False 575494.6197405253 454225.8271323192 376419.87238618295 460528.62023532996 437084.9050455286 422196.8919610777 487487.24432601273 456959.28234221 373751.14687267336 474170.98781743745 1.2136858528385943 0.9579367755565902 0.7938483839317262 0.9712290124604587 0.9217875329264398 0.8903895489355191 1.0280832375887625 0.9637014791764228 0.7882201916085445 1.0 18.855047868567667 -4.774174575750863 4.521044189841077 0.9204021433585274 1.2345014782728843 0.5741352332519969 0.07544340479450073 0.13430652225029552 6.079952223346332 0.018540376001100863 0.13443571610910549 1.6819978032158512e-05 4.774174575750863 0.3140993349143568 SILS(ph)PGGSCGPIK ddPTM_PC-9_AZD4547_30min_R2 2 SILSPGGSCGPIK 13 0 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347;P78347-5 A0A494C1K3 GTF2I General transcription factor II-I 1 S(0.025)ILS(0.972)PGGS(0.003)CGPIK;S(0.021)ILS(0.979)PGGSCGPIK 149.82 0.00011129 141674000.0 93616.0 97400.0 141297.0 175096.0 142066.0 132185.0 110166.0 162489.0 120935.0 133891.0 True False 123383.94066623453 128882.64523918841 139423.30945818036 134730.3224062329 122342.58813766173 123919.45105380166 119970.56058017936 137380.05867576212 127327.37720630426 129203.51684324844 0.9549580667833191 0.9975165412529032 1.0790984089646005 1.0427759684722024 0.9468982820807387 0.9591027712050789 0.9285394353911385 1.0632842048907507 0.9854791906382832 1.0 16.979285814308135 -3.5719019202522286 12.115592029269356 0.9969492839250155 0.4028910811328038 0.0 0.04875521325390216 0.0 0.0 0.011871804994000491 0.0 0.00026797734483896795 3.5719019202522286 -0.5940582027922117 SILS(ph)PGGSCGPIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SILSPGGSCGPIK 13 0 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347;P78347-5 A0A494C1K3 GTF2I General transcription factor II-I 1 S(0.001)ILS(0.996)PGGS(0.003)CGPIK;SILS(0.981)PGGS(0.019)CGPIK;S(0.001)ILS(0.979)PGGS(0.021)CGPIK;S(0.118)ILS(0.882)PGGSCGPIK 162.48 0.00010587 120167100.0 171414.0 171501.0 177910.0 202649.0 222125.0 193142.0 207147.0 175671.0 165831.0 146195.0 True False 200431.0046191764 188526.48586937657 182152.04912743266 191295.2335269229 178601.20078765452 183013.293512941 187524.53654559253 171059.8223888103 168255.9646535706 172698.99622101712 1.1605800207585941 1.0916478381154209 1.0547371618438228 1.1076800543884264 1.0341762528780647 1.0597241299464406 1.0858461290973687 0.9905084924170084 0.9742729739913463 1.0 17.39790017194656 -1.5228787452803465 0.17491699158889784 0.9738142741589565 1.6688904329485996 0.6701803623029662 0.03164669489924573 37.7110173158321 0.41652192948530076 0.08086819932158655 6.910670206571817 0.02999999999999938 1.5228787452803465 0.6950761587896431 SILS(ph)PGGSCGPIK ddPTM_PC-9_Lapatinib_30min_R1 3 SILSPGGSCGPIK 13 0 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347;P78347-5 A0A494C1K3 GTF2I General transcription factor II-I 1 SILS(0.688)PGGS(0.312)CGPIK;S(0.118)ILS(0.882)PGGSCGPIK;S(0.048)ILS(0.928)PGGS(0.024)CGPIK 166.86 0.00029175 152081000.0 233849.0 234827.0 286561.0 259583.0 261983.0 267734.0 245440.0 253216.0 279864.0 242960.0 True False 230514.27037734585 234283.27250922815 263001.0607374485 278673.59976350307 246573.67501839553 256283.64093843702 258147.68225285655 264981.3397704555 248342.7692214293 284955.31227614975 0.8089488437188875 0.8221754865274615 0.9229554579511562 0.9779554468998315 0.8653064687540949 0.899381867603412 0.9059233891477202 0.9299048951004026 0.871514790293717 1.0 18.120376162792816 -5.242002490518951 6.456870591468209 0.9178359678432007 0.814467433177184 0.5279938047888921 0.039997804128797845 0.12931955279259824 23.20144513267907 0.009979273679897947 0.02532700852581999 5.7279274622090745e-06 5.242002490518951 -0.1033685346660167 SILSPGGS(ph)CGPIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SILSPGGSCGPIK 13 0 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347;P78347-5 A0A494C1K3 GTF2I General transcription factor II-I 1 S(0.004)ILS(0.463)PGGS(0.533)CGPIK 121.45 0.00019705 58077000.0 67727.0 63057.0 62711.0 69420.0 81122.0 68457.0 81590.0 72952.0 59047.0 53005.0 True False 79191.8434307757 69316.88223080499 64206.26807279185 65530.622462676576 65226.726439149585 64866.99440833901 73861.20453955352 71037.08729903323 59910.45066905086 62614.38691265083 1.2647547526297906 1.1070440141417397 1.0254235685859505 1.0465745285359735 1.0417210749047667 1.0359758772186118 1.1796203425674738 1.134517014406487 0.956816054952801 1.0 15.934206562950264 -4.789582606434567 3.1922785101759676 1.0607906561012472 1.2925088677575833 0.5235854126378687 0.06050029586732023 0.28398468694625456 4.453415108773735 0.01588716394697799 0.1646806152090397 1.6233695426807186e-05 4.789582606434567 0.2317182116563361 SILVS(ph)PTGPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SILVSPTGPSR 11 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 SILVS(0.979)PT(0.021)GPSR;SILVS(0.851)PT(0.149)GPSR 107.09 0.0023526 17222600.0 63556.0 53371.0 75340.0 69200.0 110026.0 84798.0 79248.0 67040.0 68401.0 60989.0 True False 74314.77551178096 58669.32016334893 77136.39132854104 65322.94834942699 88467.19512824953 80351.04360165252 71741.05573416535 65280.27103475155 69401.23522302156 72045.82291134166 1.0314931873737 0.8143334032778885 1.0706573707050824 0.9066861298789283 1.2279295530722958 1.1152769217520233 0.9957698147531557 0.9060937663948169 0.9632929768659249 1.0 16.136627167481944 -4.408422240278158 22.766205221428894 1.0020105983772387 12.925126519705632 0.006877449829365667 0.11119018844611865 8897.475254675332 1769534.0315753156 0.02808140543580379 750.46400414838 3.904610876730452e-05 4.408422240278158 11.923115921328392 SILVS(ph)PTGPSR ddPTM_PC-9_Lapatinib_30min_R1 1 SILVSPTGPSR 11 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 S(0.001)ILVS(0.87)PT(0.129)GPSR 76.165 0.020918 19241000.0 36690.0 28375.0 41734.0 30995.0 29563.0 30612.0 30829.0 22470.0 32548.0 21606.0 True False 36166.793871878035 28309.299430854822 38302.79161789875 33274.47569628895 27824.162463094253 29302.796120057363 32425.174772544484 23514.038230767954 28882.101494365397 25340.568311814674 1.4272289960843456 1.1171532967418107 1.5115206236333945 1.3130911385588464 1.0980086208296143 1.1563590744882923 1.2795756738189141 0.9279207135936598 1.1397574489637445 1.0 14.62916125964943 -6.907606346567294 0.5780101904964946 1.0168480671049347 1.355582841975701 0.4443068954617564 0.1300887979444819 0.8461957667165271 0.6064746205609814 0.11182630355029854 0.11407837996833853 1.2370682294466985e-07 6.907606346567294 0.3387347748707663 SILVSPT(ph)GPSR ddPTM_PC-9_AZD4547_30min_R2 1 SILVSPTGPSR 11 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 S(0.002)ILVS(0.173)PT(0.824)GPSR 91.12299999999999 0.02045 22549000.0 54483.0 37589.0 55430.0 77625.0 74842.0 62904.0 54086.0 70321.0 45990.0 55553.0 True False 71807.46068319996 49738.90915704168 54694.96198268139 59729.755544294756 64451.48016695664 58970.602935948365 58899.54922153455 59454.50526582274 48420.937509554125 53608.10637901722 1.3394888484870295 0.9278244003878864 1.020274090563467 1.11419260217842 1.2022711586056625 1.1000314489569452 1.098706020412399 1.109058112321122 0.9032390953564179 1.0 15.710163554645328 -8.250184048592374 23.58277846973642 0.951619554965777 1.1066280052919144 0.2794283796248569 0.10375464161870371 399.35171328928885 836752.2879181243 0.07021859769926328 0.025934167855721245 5.62103062430551e-09 8.250184048592374 0.15500845032613741 SILYDER ddPTM_PC-9_AZD4547_30min_R2 2 SILYDER 7 0 P25787;A0A024RA52 P25787 PSMA2 Proteasome subunit alpha type-2;Proteasome subunit alpha type 0 ; 110.63 0.0048145 7807300.0 75733.0 86322.0 126405.0 184915.0 157517.0 121597.0 106483.0 164242.0 113401.0 132596.0 False True 99814.51865574178 114223.89838128585 124728.78710844008 142285.70365827068 135648.48349133533 113993.5203675842 115959.78071509587 138862.17280569463 119395.14534727021 127953.85439908104 0.7800821563719822 0.8926960341892303 0.974795075101199 1.1120079526052367 1.0601359695523915 0.890895556862591 0.9062625058048168 1.0852519719538196 0.9331109712012529 1.0 16.965264081280253 -4.977497006764669 2.2475020476463 0.9981991040219631 0.7679352790093206 0.4882719596642564 0.07001784876338916 0.37479707797083267 3.0171732938162297 0.020130291050829155 0.14713444020538163 1.053180945816355e-05 4.977497006764669 -0.23026382501264253 SILYDER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SILYDER 7 0 P25787;A0A024RA52 P25787 PSMA2 Proteasome subunit alpha type-2;Proteasome subunit alpha type 0 110.63 0.043476999999999995 3474600.0 29503.0 30204.0 40733.0 44427.0 55140.0 34709.0 41096.0 36479.0 31181.0 31058.0 False True 34497.27518918861 33202.45350871804 41704.22920076271 41937.899224277346 44335.71282580196 32888.798938297594 37203.08937072557 35521.464902695385 31636.963136343515 36688.56954500728 0.9402731045937747 0.9049808678963979 1.1367090545626894 1.1430780688473152 1.2084339448397854 0.896431759160074 1.014023981640579 0.9681888758055786 0.8623111647221141 1.0 15.163043035824245 -6.796697773204726 24.999986261363617 0.9503175117978692 1.0658444191981638 0.2794441347980603 0.09510993212999651 280.5941223168678 198953.60148255923 0.036904706650679055 0.0325480620318488 1.5969901107014118e-07 6.796697773204726 0.11552690740029459 SILYDER ddPTM_PC-9_Lapatinib_30min_R1 2 SILYDER 7 0 P25787;A0A024RA52 P25787 PSMA2 Proteasome subunit alpha type-2;Proteasome subunit alpha type 0 ; 128.57 0.020554 13473000.0 177193.0 170603.0 167946.0 143697.0 169647.0 159348.0 131663.0 145642.0 186054.0 118749.0 False True 174666.19532678352 170207.97923531735 154138.12817030813 154264.95673913945 159668.69699883496 152533.0574983305 138479.86590799334 152409.05901226093 165098.63928452303 139274.60642690325 1.254113724015118 1.2221034659656291 1.1067209746609898 1.1076316113670277 1.1464307894679662 1.0951964712848485 0.994293715564531 1.0943061547422226 1.1854180996818917 1.0 17.087572713556362 -4.235133657202023 0.6151781719947296 1.0789097552063005 1.5442173724532926 0.5374101125838027 0.05491579984384493 5.247110549991995 0.9241241032702632 0.026456585304701474 2.0033517149633497 5.81924098947716e-05 4.235133657202023 0.4653076172469921 SIMVQS(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 1 SIMVQSPEK 9 0 Q14191 Q14191 WRN Werner syndrome ATP-dependent helicase 1 SIMVQS(1)PEK 87.184 0.021925 0.0 80020.0 80093.0 82242.0 80935.0 92320.0 94822.0 99435.0 90346.0 87631.0 99195.0 True False 105464.69548060228 105981.49594601993 81151.41734403188 62276.686183285085 79502.9615591974 88892.76535025577 108284.52236888095 76385.10164454479 92262.9957577678 95722.21324260838 1.101778698046832 1.1071776587259776 0.8477804116203754 0.6505980594644687 0.8305591655898802 0.9286534686045824 1.1312371360912157 0.7979872075350619 0.9638619149342778 1.0 16.54656613410682 -5.255733202054734 24.467282006748867 0.8853952527596147 1.1044782200437337 0.3212296257765118 0.12198652012274175 410.4973898647018 1760135.719909131 0.03351313615467206 0.08360464837778837 5.549665380612454e-06 5.255733202054734 0.21908296728411902 SIMVQS(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SIMVQSPEK 9 0 Q14191 Q14191 WRN Werner syndrome ATP-dependent helicase 1 SIMVQS(1)PEK;SIMVQS(1)PEK 76.92699999999999 0.02096 19035200.0 182560.0 198114.0 168044.0 255150.0 245880.0 182194.0 226100.0 204368.0 166617.0 162761.0 True False 213463.80227564226 217781.4486301866 172050.80627041883 240854.7727074612 197701.5790643487 172639.4259057938 204682.1711777554 199003.55654579503 169053.4584166049 192268.28088463313 1.1102393036099756 1.1326956668472121 0.8948475821326691 1.2527015459818953 1.0282589419051171 0.8979090316482454 1.0645654615311768 1.0350306125907647 0.8792581784097927 1.0 17.552761250713665 -6.517583178813728 24.98618729199462 0.9808918759228208 1.092497252155709 0.25928022581658616 0.09704352312776318 353.3352526585874 1667159.9067147865 0.03087706663797039 0.03176118076274724 3.036804408342372e-07 6.517583178813728 0.11160537623288824 SIMVQS(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 1 SIMVQSPEK 9 0 Q14191 Q14191 WRN Werner syndrome ATP-dependent helicase 1 SIMVQS(1)PEK 84.821 0.012912 2932800.0 17436.0 19918.0 22460.0 22635.0 21873.0 21488.0 16674.0 19389.0 21480.0 18765.0 True False 17187.359442629207 19871.881094758282 20613.425498107197 24299.653408146503 20586.473143972555 20569.008330974542 17537.298133491422 20289.88372302446 19060.696205572345 22008.505247209207 0.7809416972926253 0.9029182523551045 0.936611790149678 1.1041028518385103 0.9353871565895202 0.9345936082407413 0.7968418543878732 0.9219110291734748 0.8660604612386996 1.0 14.425773544512332 -9.92348486167743 15.239926067415572 0.999997906874186 0.9138374307803997 0.09221257496469526 0.08451692293644716 0.0 0.0 0.08673558500312077 0.021036469321623893 1.192655837864847e-10 9.92348486167743 -0.0861604760937863 SINEENGEVS(ph)EDQSQNK ddPTM_PC-9_AZD4547_30min_R2 1 SINEENGEVSEDQSQNK 17 0 Q13523 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 S(0.07)INEENGEVS(0.905)EDQS(0.024)QNK 74.14699999999999 0.009801700000000002 7671800.0 13280.0 16906.0 13855.0 14475.0 13459.0 15936.0 17300.0 16930.0 19974.0 16575.0 True False 17502.7637588403 22370.53388515116 13671.273647303824 11138.012386520671 11590.45016925082 14939.519400789677 18839.666485459216 14313.857512697203 21029.784862270808 15994.71429503736 1.0942842389045262 1.3986204112499845 0.8547369709220487 0.6963558198708454 0.7246425259904117 0.9340285249999698 1.1778682718518174 0.8949117345058378 1.3147959053445342 1.0 13.965307602149078 -9.581985535784613 15.05283552415427 1.0000130806855092 0.9985852197150248 0.0 0.22434646287052207 0.0 0.0 0.23277172925539194 0.056455436845744576 2.6182702084832544e-10 9.581985535784613 -0.001427860970484418 SINHQIES(ph)PSER ddPTM_PC-9_AZD4547_30min_R2 3 SINHQIESPSER 12 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 SINHQIES(0.9)PS(0.1)ER;SINHQIES(0.681)PS(0.319)ER;SINHQIES(0.915)PS(0.085)ER 149.32 0.00014082 27383600.0 19688.3 18717.600000000002 66560.0 128156.0 85005.0 77986.0 40530.5 87901.0 49449.0 71618.0 True False 25948.76985791983 24767.698157382296 65677.37091046866 98611.61419046251 73203.5230431062 73109.52309174079 44137.635982017644 74317.92021403424 52062.77318786571 69110.67561882272 0.3754668815718034 0.35837731197981026 0.9503216445561852 1.4268651450370864 1.0592216381569965 1.0578615016726731 0.6386514903349677 1.075346457672211 0.7533246162288434 1.0 16.076620962416456 -5.278332856270689 5.702490830418673 1.0071642866810127 0.3621076455195243 0.6196720672984042 0.19697677270224864 0.1017137101790375 12.411895776190343 0.05423746839174502 0.12481791168459384 5.268259315114617e-06 5.278332856270689 -0.6450566411614884 SINHQIES(ph)PSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SINHQIESPSER 12 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 SINHQIES(0.5)PS(0.5)ER;SINHQIES(0.978)PS(0.022)ER;SINHQIES(0.999)PS(0.001)ER 124.42 0.00032302 12966800.0 9750.5 10251.300000000001 43381.1 26400.6 46925.1 43071.7 29474.8 29197.8 27758.6 25586.9 True False 11401.067068846683 11268.981315518518 44415.46994773788 24921.45997390003 37730.463509648886 40812.9442286056 26682.73356492754 28431.388687626295 28164.5170108882 30225.602424211036 0.3771990019862865 0.37282900626297993 1.469465168117232 0.8245149136858119 1.2482948389285493 1.3502772800291314 0.8827858313769912 0.9406392729116441 0.931809947593571 1.0 14.88348347355687 -5.239293262217472 24.43885735906345 1.0782097701247348 0.37501366939667524 0.6631212247167496 0.20126275818026565 350.99076880870376 387326.0761788799 0.051017035849470385 0.13471931431538814 5.763771268388567e-06 5.239293262217472 -0.7031961007280596 SINHQIES(ph)PSER ddPTM_PC-9_Lapatinib_30min_R1 2 SINHQIESPSER 12 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 SINHQIES(0.5)PS(0.5)ER;SINHQIES(0.5)PS(0.5)ER 134.06 5.6244e-05 16234500.0 53859.0 42158.0 73863.0 38438.0 59653.0 59680.0 49219.0 39667.0 73904.0 41452.0 True False 53090.96078346903 42060.385741179816 67790.26925942532 41264.85874540908 56144.32782231041 57127.625520874935 51767.31898958344 41510.073631502986 65580.15327637886 48616.92296868188 1.0920263468271993 0.8651387865142007 1.39437597280878 0.8487756160954724 1.1548309599617719 1.1750563802171414 1.064800399295755 0.8538194335795996 1.348916164822368 1.0 15.569170965670052 SINKLDS(ph)PDPFK ddPTM_PC-9_Lapatinib_30min_R1 1 SINKLDSPDPFK 12 1 P42566;B1AUU8;P42566-2 P42566 EPS15 Epidermal growth factor receptor substrate 15 1 SINKLDS(1)PDPFK 86.189 0.044680000000000004 5420100.0 17008.0 21226.0 17969.0 20865.0 40471.0 30881.0 46003.0 42309.0 32373.0 47360.0 True False 16765.4628011148 21176.852501121557 16491.658182345884 22399.481703599577 38090.57534904738 29560.291617126997 48384.81024559229 44274.83059659817 28726.811837197092 55546.11289676676 0.3018296317561168 0.3812481449508274 0.2969003107921497 0.40325921176931556 0.6857469112166185 0.5321757018725184 0.8710746391114019 0.7970824291320542 0.5171705154343793 1.0 15.761398335254306 -6.407127666376556 1.063371613279125 0.7720071643779606 0.31044596617323167 0.6807927280657509 0.1329709365155902 0.3031233367247344 0.7259102672183162 0.06064408544674705 0.07899984736986829 3.916267365339809e-07 6.407127666376556 -0.4615611982047289 SINYCETPKFKLDT(ph)VLQNFS(ph)S(ph)DK ddPTM_PC-9_AZD4547_30min_R2 1 SINYCETPKFKLDTVLQNFSSDK 23 2 A0A087X1N7;P20929-4;P20929;P20929-3;P20929-2 A0A087X1N7 NEB Nebulin 3 S(0.002)INY(0.004)CET(0.012)PKFKLDT(0.983)VLQNFS(1)S(1)DK 50.232 0.025227 4900600.0 9748.5 9189.3 15180.0 13704.0 14941.0 16448.0 13885.0 15315.0 12368.0 13535.0 True False 12848.320218603518 12159.561518444307 14978.703281564194 10544.75452468942 12866.700050432906 15419.503959851194 15120.738101190822 12948.418653689168 13021.747230227575 13061.143769733362 0.9837055961650908 0.9309721822848092 1.146814057454478 0.8073377577486606 0.985112810736297 1.1805630679590917 1.1576886655386311 0.9913694299648235 0.9969836838028625 1.0 13.67299361936409 -6.550445356530133 24.946051966234457 1.0719194097536195 0.9672953138816532 0.1893095413406739 0.09789685377268569 348.88886708439856 315720.0479921431 0.03298093061793736 0.03298153073742646 2.815494241822523e-07 6.550445356530133 -0.1046240958719663 SIPAGAEPGEKGS(ph)AR ddPTM_PC-9_AZD4547_30min_R2 4 SIPAGAEPGEKGSAR 15 1 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 SIPAGAEPGEKGS(1)AR;SIPAGAEPGEKGS(1)AR;SIPAGAEPGEKGS(1)AR;SIPAGAEPGEKGS(1)AR 138.98 0.00027398 64799100.0 129440.0 149865.0 186051.0 241270.0 213070.0 233519.0 171901.0 266553.0 199002.0 213751.0 True False 170599.2274807449 198305.93048019483 183583.84217643607 185648.92908434157 183488.90835591586 218917.02001462143 187199.8559836372 225363.35862858748 209520.83944936472 206267.6425507408 0.8270770217329573 0.9614010613972697 0.8900273446004764 0.9000390307882288 0.8895670987793373 1.0613250692520468 0.9075580331878131 1.0925773710394213 1.0157717267642872 1.0 17.654157996131808 -6.749436423757888 24.993669074051788 1.0144894996299083 0.8975445368577712 0.559841077550618 0.05395083050350716 170.7420528342495 355534.36922002106 0.017135245839018064 0.01700782602749219 1.780588549612401e-07 6.749436423757888 -0.11694496277213706 SIPAGAEPGEKGS(ph)AR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SIPAGAEPGEKGSAR 15 1 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 SIPAGAEPGEKGS(1)AR;SIPAGAEPGEKGS(1)AR;SIPAGAEPGEKGS(1)AR;SIPAGAEPGEKGS(1)AR 87.419 0.0024388 53472000.0 237340.0 210398.0 223942.0 209874.0 257062.0 200543.0 204180.0 191653.0 169439.0 139981.0 True False 277516.9743213246 231284.9229680595 229281.62658476408 198115.44020068858 206692.54643500687 190026.17204422542 184838.5922648123 186622.31182313862 171916.72482790472 165358.44721101393 1.6782751592193241 1.39868828517068 1.3865734134052297 1.19809688311764 1.2499666628536157 1.1491772887884766 1.1178055635037485 1.128592551337821 1.0396609772739447 1.0 17.33523722083163 -1.52287874528034 0.2984202660421645 1.0306299460978852 6.301499890909044 0.9440856548568041 0.04570826148215484 10.812612629272888 0.15400781565518776 0.04415315963584251 30.36873614983141 0.02999999999999983 1.52287874528034 5.2708699448111584 SIPAGAEPGEKGS(ph)AR ddPTM_PC-9_Lapatinib_30min_R1 3 SIPAGAEPGEKGSAR 15 1 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 SIPAGAEPGEKGS(1)AR;SIPAGAEPGEKGS(1)AR;SIPAGAEPGEKGS(1)AR 92.679 0.0016585999999999999 65714000.0 231478.0 195001.0 233388.0 200230.0 182079.0 161918.0 145505.0 114805.0 165727.0 112016.0 True False 228177.08127213374 194549.48716532602 214199.73954373284 214955.5821476994 171369.47120108703 154993.14458929334 153038.53693856703 120139.25941625806 147061.08007732258 131377.816348062 1.736800683820314 1.4808397077471738 1.630410258732334 1.6361634568366783 1.3044018843110794 1.1797512616488217 1.1648735014221794 0.9144562054370777 1.1193752808899682 1.0 17.003362166029262 -6.616429341892099 1.2883218634800269 1.0338652675203168 1.6277889280431566 0.8940279990639516 0.08896602042555812 0.12922026580074839 0.4492394017269395 0.039698307858873884 0.04089548430868936 2.4186368091956775e-07 6.616429341892099 0.5939236605228397 SIPLDEGEDEAQR ddPTM_PC-9_AZD4547_30min_R2 1 SIPLDEGEDEAQR 13 0 Q14204;A0A2R8YFZ7;A0A2R8YGC7 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 113.38 0.0018027000000000002 0.0 4822.5 4432.2 6177.2 7439.8 7952.1 6900.6 4747.9 8286.0 7900.6 5700.7 False True 6355.954685768622 5864.821973605048 6095.2862918892215 5724.669053764182 6848.088178237574 6469.104391132603 5170.453902098951 7005.58909333781 8318.209586605431 5501.120228158035 1.1553927967680166 1.0661141240988279 1.1080081945291593 1.040636964169932 1.2448533924390432 1.1759612811259503 0.9398910926602667 1.2734840910182257 1.5120937630171836 1.0 12.42550971839827 -7.967819226042283 23.855923697419293 1.3016275938041106 1.1086256497589542 0.1971073088510461 0.13980553926465264 138.63892281393174 102774.05138720633 0.07229513629235393 0.034728897170599494 1.0769133827661394e-08 7.967819226042283 -0.19300194404515647 SIPLDEGEDEAQR ddPTM_PC-9_Lapatinib_30min_R1 1 SIPLDEGEDEAQR 13 0 Q14204;A0A2R8YFZ7;A0A2R8YGC7 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 174.57 0.0008179 3799900.0 11194.0 9946.2 10415.0 9474.5 7169.4 9517.5 7580.6 8133.7 11466.0 5222.5 False True 11034.371507271813 9923.170184992701 9558.718903062629 10171.286336005474 6747.709987582722 9110.458711376117 7973.086375839335 8511.621395531698 10174.57833766725 6125.202166456175 1.8014705812813865 1.6200559451466883 1.5605556589478196 1.660563367476607 1.1016305754829816 1.4873727370613639 1.301685423462893 1.3896066063165096 1.6611008193961212 1.0 12.580541746692464 -1.5228787452803376 0.07144464945978594 0.6857200034654437 3.302860334713984 0.46525454017309453 0.17968394642776167 236.37275868867022 1.2496474530313637 7.835855364117793 62.02269294297019 0.029999999999999995 1.5228787452803376 2.61714033124854 SIPLECPLS(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 3 SIPLECPLSSPK 12 0 Q92667-2;Q92667;I3L2A2;I3L2N7 Q92667-2 AKAP1 A-kinase anchor protein 1, mitochondrial 1 SIPLECPLS(0.69)S(0.31)PK;SIPLECPLS(0.95)S(0.05)PK;SIPLECPLS(0.739)S(0.261)PK 221.09 2.0915e-11 20837900.0 162805.0 167109.0 190529.0 208417.0 214035.0 138115.0 198804.0 202376.0 171968.0 164861.0 True False 214573.60344563244 221123.7162553957 188002.46097056297 160369.68066055106 184319.93476302878 129478.64721636983 216497.1708656204 171103.4393378389 181057.87740037002 159089.2665697832 1.3487622897017473 1.389934852445885 1.1817419554706239 1.0080484002370218 1.1585944088954507 0.8138741852805957 1.3608534097468836 1.0755184370831565 1.138089836632382 1.0 17.27947697768021 -5.408836801536254 3.5830243177814856 1.0864537080089105 1.3690522081327083 0.4303058902421414 0.13157358572402095 0.21979923333832432 5.070767528855348 0.034458575570089384 0.07848958056496981 3.900885459680022e-06 5.408836801536254 0.28259850012379784 SIPLECPLS(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 2 SIPLECPLSSPK 12 0 Q92667-2;Q92667;I3L2A2;I3L2N7 Q92667-2 AKAP1 A-kinase anchor protein 1, mitochondrial 1 SIPLECPLS(0.738)S(0.262)PK;SIPLECPLS(0.795)S(0.205)PK 228.61 1.2805e-15 11006600.0 143319.0 135256.0 60147.0 47140.0 81009.0 100146.0 106806.0 81616.0 126743.0 57057.0 True False 141275.24477851443 134942.82304210382 55201.945834134174 50606.83285443011 76244.20988982177 95862.98903172814 112335.89207422838 85408.17731385675 112467.86867704178 66919.22642632654 2.1111308710964964 2.016503032811752 0.8249041237036372 0.7562375651509473 1.1393468508450466 1.4325178898663256 1.678678880095879 1.2762875764543584 1.680651057747375 1.0 16.03013314773873 -6.9695562029415 24.748384465087078 1.4495957948603775 1.3356938427169531 0.0 0.4514498096094418 1365.382156002514 1109942.3052677696 0.17608142179639094 0.1552873004759979 1.0726148295637268e-07 6.9695562029415 -0.11390195214342436 SIPLECPLSS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SIPLECPLSSPK 12 0 Q92667-2;Q92667;I3L2A2;I3L2N7 Q92667-2 AKAP1 A-kinase anchor protein 1, mitochondrial 1 SIPLECPLS(0.328)S(0.672)PK;SIPLECPLS(0.458)S(0.542)PK 180.09 0.00074934 10038800.0 48661.0 40604.0 29252.2 46175.0 80355.0 53873.0 76909.0 70713.0 51704.0 65362.0 True False 56898.346201440785 44634.89677751247 29949.683387586294 43587.964451369815 64610.01458319397 51047.80504200372 69623.62274705892 68856.85867661652 52460.073185642046 77211.61319469268 0.7369143558491513 0.5780852766922963 0.3878909162546154 0.5645260168500914 0.8367914088296123 0.6611415424423823 0.9017247518388162 0.8917940686330533 0.6794324197496241 1.0 16.23653023531151 -6.2571421394097895 21.5921406527984 0.818365664794226 0.5548731647598169 0.5186704663107509 0.12302313954669471 46.407615546255485 233178.1571671106 0.03713360896801605 0.046083253367303414 5.531690339510484e-07 6.2571421394097895 -0.26349250003440916 SIPTDNQIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SIPTDNQIK 9 0 B4DLR8;P15559-3;P15559-2;P15559;H3BNV2 B4DLR8 NQO1 NAD(P)H dehydrogenase [quinone] 1 0 105.52 0.012121 3899700.0 29679.0 26593.0 26129.0 29613.0 33967.0 25405.0 25389.0 23875.0 31170.0 21799.0 False True 34703.068513030164 29232.977292985655 26752.014454784316 27953.87961664136 27311.410184149725 24072.71707705351 22983.97011955789 23248.3065476535 31625.80228215345 25750.986139210934 1.3476403709521605 1.135217779037701 1.0388733973200786 1.0855459851332097 1.0605966713858286 0.9348269983493203 0.8925471822828672 0.9028122815169936 1.2281394627445725 1.0 14.652340061200942 -1.522878745370287 0.692034411449712 0.9934802454336225 43.01260005361147 0.5478321606451408 0.09261861730126254 207.5503862847395 1.1368668824688288 0.03765200121641087 13475.334288497203 0.029999999993786514 1.522878745370287 42.01911980817785 SIPTDNQIK ddPTM_PC-9_Lapatinib_30min_R1 3 SIPTDNQIK 9 0 B4DLR8;P15559-3;P15559-2;P15559;H3BNV2 B4DLR8 NQO1 NAD(P)H dehydrogenase [quinone] 1 0 ;; 129.38 0.0059886 69507000.0 238602.0 240284.0 221824.0 230497.0 228789.0 208506.0 236648.0 176925.0 196187.0 216442.0 False True 235199.49172575196 239727.63716100444 203586.48698540244 247448.51829545147 215332.08083648048 199588.68443122567 248900.47551244302 185145.58139646708 174090.35411930282 253853.71130916342 0.9265158681856226 0.9443534858115384 0.8019834964613083 0.974768172658657 0.8482526401760256 0.7862350461685808 0.980487833834787 0.7293396674866097 0.6857900687033156 1.0 17.95363782667762 -6.630958285697242 0.9170973547673156 0.8159671664356221 0.9120826534907981 0.07987390891595136 0.10268317544739441 1.3198052268063538 2.4245693772944836 0.05896649635685477 0.06257150675439094 2.3390618964765428e-07 6.630958285697242 0.09611548705517603 SIQADGLVWGSSK ddPTM_PC-9_Lapatinib_30min_R1 1 SIQADGLVWGSSK 13 0 P24534 P24534 EEF1B2 Elongation factor 1-beta 0 149.82 0.00057136 6994900.0 46243.0 51692.0 39817.0 51615.0 52916.0 43795.0 52435.0 49426.0 44694.0 55610.0 False True 45583.56634007241 51572.31034994701 36543.39995806476 55410.93928259251 49803.584916858774 41921.98994113131 55149.82773357453 51722.51239848407 39660.0910713152 65222.11440433272 0.6988974024590083 0.7907181608715379 0.5602915558903925 0.8495728755293396 0.7635996681755891 0.6427572967236772 0.8455694550422442 0.7930210921688262 0.6080773589376393 1.0 15.993073591430052 -10.797018217666205 3.9347463408722354 1.000368102694355 0.7324424912700772 0.42771029219356715 0.09424710338685277 22306228.47465781 15302371.21245477 65785.27345352847 0.0219606404789197 1.595812205138571e-11 10.797018217666205 -0.26792561142427773 SIQCLTVHK ddPTM_PC-9_Lapatinib_30min_R1 1 SIQCLTVHK 9 0 O75083;O75083-3 O75083 WDR1 WD repeat-containing protein 1 0 72.096 0.029064999999999997 0.0 36764.0 32927.0 50832.0 47356.0 42006.0 45282.0 39297.0 38269.0 46126.0 28694.0 False True 36239.738618308125 32850.75955452886 46652.78917719437 50838.71821498502 39535.28966697351 43345.39441749764 41331.606378302284 40047.11744785307 40930.80415168671 33653.71966764834 1.0768419947690284 0.9761405241070163 1.386259517162442 1.5106418760555846 1.1747673082621883 1.2879822749330738 1.228143776868587 1.189975962340673 1.216234180230422 1.0 15.038478350937618 -9.264646966856613 0.9228767177902124 0.9983300517444189 1.2383758896221926 0.1900137212149169 0.1410965419052686 6.356610632111694 6.413178092364429 0.1762838192828331 0.04887698110832143 5.436921131668245e-10 9.264646966856613 0.24004583787777367 SIQEELQQLR ddPTM_PC-9_Lapatinib_30min_R1 2 SIQEELQQLR 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 115.23 0.0052586 7723300.0 28614.0 25577.0 34776.0 28654.0 31891.0 33414.0 32449.0 30386.0 39710.0 27057.0 False True 28205.95911283505 25517.778027946206 31916.851519242042 30761.310746941883 30015.234080118375 31984.96111183837 34129.05044582362 31797.844489546726 35237.44163516192 31733.766398813706 0.8888311194567017 0.8041206866922714 1.0057694103538615 0.9693558073236407 0.945845308839244 1.007915691754574 1.0754806100513632 1.0020192400085044 1.1104084271723633 1.0 14.953731140717323 -5.329148260660881 0.5314599320632881 1.0490589605072855 0.7749107601804431 0.6085080422744562 0.05196145125224034 1.645288627015884 0.535805430492997 0.033150366011856065 0.2615122212131472 4.6865336464115845e-06 5.329148260660881 -0.2741482003268424 SIQEIQELDKDDESLR ddPTM_PC-9_AZD4547_30min_R2 1 SIQEIQELDKDDESLR 16 1 J3KTF8;J3QQX2;P52565;J3KRE2;J3KRY1;P52565-2;J3KS60 J3KTF8 ARHGDIA Rho GDP-dissociation inhibitor 1 0 155.37 4.9758999999999996e-05 9179100.0 14556.0 17256.0 18814.0 19829.0 20948.0 21402.0 18649.0 22304.0 16930.0 19340.0 False True 19184.50521639151 22833.664540528098 18564.514067150776 15257.730404996084 18039.731788800524 20063.729556708124 20308.72487209994 18857.429294931982 17824.885236719972 18662.912486637848 1.0279480884951429 1.2234780909397929 0.9947275957298989 0.8175428361420124 0.9666086041884671 1.075058867209136 1.0881862563863198 1.0104226394692364 0.9550966522230718 1.0 14.187886526625968 -5.357646734554221 9.355314456376735 0.9883164817769748 1.125440532380188 0.30729994293390017 0.08246028259427172 0.4507033897609336 40.4993607681833 0.02316986109395686 0.04832248280903163 4.388875541774221e-06 5.357646734554221 0.1371240506032131 SIQEIQELDKDDESLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SIQEIQELDKDDESLR 16 1 J3KTF8;J3QQX2;P52565;J3KRE2;J3KRY1;P52565-2;J3KS60 J3KTF8 ARHGDIA Rho GDP-dissociation inhibitor 1 0 ; 125.33 0.00018913 5996600.0 31829.0 33809.0 28351.0 29437.0 33168.0 33430.0 32266.0 34185.0 30552.0 22868.8 False True 37217.021048594535 37165.33408410302 29026.995361766254 27787.74032604167 26668.968498480222 31676.871949848424 29209.53089438951 33287.6799720015 30998.765201294584 27014.732410678793 1.377656475837711 1.3757431877952544 1.0744876136656465 1.0286143095408677 0.9872009129336446 1.1725776686696594 1.0812445020866883 1.2322046898692596 1.1474763003405106 1.0 14.721458771242773 -5.258639260036214 24.25189261924604 1.0954735683586743 1.376699884777638 0.7106161177356866 0.07300532031651842 87.8004815457519 760424.4049413506 0.020117240091287663 0.04846944747757602 5.512654063290582e-06 5.258639260036214 0.2812263164189637 SIQEIQELDKDDESLR ddPTM_PC-9_Lapatinib_30min_R1 3 SIQEIQELDKDDESLR 16 1 J3KTF8;J3QQX2;P52565;J3KRE2;J3KRY1;P52565-2;J3KS60 J3KTF8 ARHGDIA Rho GDP-dissociation inhibitor 1 0 ;; 197.47 7.8851e-12 25730800.0 74838.2 76010.7 82185.9 80030.9 79237.8 70624.4 77627.9 68846.1 75279.8 72192.0 False True 73770.99354435486 75834.70189423338 75428.8925487483 85916.63936125608 74577.18839150868 67603.95904551743 81647.09282576815 72044.94114104463 66800.99619256271 84670.29101020671 0.8712736505826113 0.8956471152920895 0.8908542966936964 1.0147200196926112 0.880795229374122 0.7984377783391344 0.964294463283773 0.850888077523672 0.7889543710734392 1.0 16.36956822713679 -6.496769696597099 24.965512976110467 0.8723410749493076 0.918718866234498 0.057072674502344656 0.07099542758784164 1919.4351552768433 1835369.046296091 0.021756560695087152 0.024586814533871227 3.1858865277578787e-07 6.496769696597099 0.046377791285190484 SIQFVDWCPTGFK ddPTM_PC-9_AZD4547_30min_R2 1 SIQFVDWCPTGFK 13 0 P68363;P68363-2;P68366-2;P68366 P68363;P68366-2 TUBA1B;TUBA4A Tubulin alpha-1B chain;Tubulin alpha-4A chain 0 93.839 0.018073 3792000.0 17022.0 14749.0 19198.0 25529.0 23374.0 20421.0 17838.0 23137.0 17051.0 18261.0 False True 22434.64192040509 19516.325817585144 18943.421976249643 19643.683469118227 20128.923564608725 19144.071641787526 19425.54744321511 19561.708285367717 17952.28104969359 17621.687948215815 1.2731267280599294 1.1075173885122147 1.0750060965736061 1.1147447126997354 1.1422812402399152 1.0863926144899105 1.1023658743873022 1.110092764260323 1.0187605808506697 1.0 14.105064503460737 -1.5228787452803376 0.1206453144455486 0.9751169255868803 1.6401823417323267 0.5687694693724386 0.04618292201343493 81.78969672566313 0.6802412614241513 0.3268325548596729 9.144962018641756 0.029999999999999995 1.5228787452803376 0.6650654161454463 SIQFVDWCPTGFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SIQFVDWCPTGFK 13 0 P68363;P68363-2;P68366-2;P68366 P68363;P68366-2 TUBA1B;TUBA4A Tubulin alpha-1B chain;Tubulin alpha-4A chain 0 ; 178.32 0.00057954 8404200.0 34090.0 41368.0 41181.0 44393.0 46125.0 42069.0 41065.0 41973.0 35388.0 29403.0 False True 39860.76369180896 45474.7416484124 42162.91121981221 41905.80413404785 37087.137361082976 39862.82758175808 37175.02591514613 40871.25322406957 35905.482552481444 34733.53114598006 1.1476162191595172 1.309246141928057 1.213896480683393 1.206494207511576 1.067761789183226 1.147675639836915 1.070292155407546 1.176708842308418 1.033741211095867 1.0 15.084041467719173 -6.578835728394349 0.2503196541803136 0.9905706898257116 1.3153599288072408 0.5635680054437616 0.059415865479737186 2.882197028483371 0.35922735855835597 0.10944785194964521 0.30134348530461563 2.6373287650765744e-07 6.578835728394349 0.3247892389815292 SIQFVDWCPTGFK ddPTM_PC-9_Lapatinib_30min_R1 2 SIQFVDWCPTGFK 13 0 P68363;P68363-2;P68366-2;P68366 P68363;P68366-2 TUBA1B;TUBA4A Tubulin alpha-1B chain;Tubulin alpha-4A chain 0 ; 168.02 0.00036386 19526300.0 83212.0 65108.0 86712.0 74870.0 77139.0 82598.0 80714.0 69295.0 75238.0 77036.0 False True 82025.3816207882 64957.24642622358 79582.87407799959 80376.18955899827 72601.83568110914 79065.47608534232 84892.97598336484 72514.69867383482 66763.9041487362 90351.56995598238 0.9078467774356268 0.7189387683896312 0.8808134060843756 0.8895937236968441 0.8035481366453223 0.8750869091025376 0.9395849571260703 0.8025837150274494 0.7389346325831675 1.0 16.463262049239567 SIQPQVS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 SIQPQVSPR 9 0 A0A2R8YCL1;Q13322-3;Q13322-2;Q13322-4;Q13322 A0A2R8YCL1 GRB10 Growth factor receptor-bound protein 10 1 SIQPQVS(1)PR;SIQPQVS(1)PR;SIQPQVS(1)PR;SIQPQVS(1)PR 122.55 0.0015497 52596000.0 139895.0 117105.0 205702.0 294153.0 244933.0 213812.0 184997.0 229079.0 169173.0 224032.0 True False 184378.7000032356 154956.90113691156 202974.25707670077 226340.5704685466 210928.28080133113 200442.30183996196 201461.37461332354 193680.10426173435 178115.1394064753 216188.70787003348 0.8528599935667261 0.7167668592111076 0.9388753884348258 1.0469583388444883 0.9756674290691225 0.927163605420419 0.9318774167170489 0.8958844620976658 0.8238873397289236 1.0 17.721931643553035 -5.27978523453523 23.278774415349258 0.9428033551874045 0.7848134543920109 0.49148667414307223 0.06417339536300745 246.9974280454525 313411.4995561431 0.017587035718575665 0.036756486852128366 5.250670499889269e-06 5.27978523453523 -0.15798990079539366 SIQPQVS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SIQPQVSPR 9 0 A0A2R8YCL1;Q13322-3;Q13322-2;Q13322-4;Q13322 A0A2R8YCL1 GRB10 Growth factor receptor-bound protein 10 1 SIQPQVS(1)PR;SIQPQVS(1)PR 87.641 0.010734 25394000.0 47163.0 54716.0 61407.0 63734.0 87480.0 75707.0 72503.0 71995.0 67548.0 54150.0 True False 55146.764388289404 60147.842874553535 62871.17576734435 60163.190608415876 70338.92198043437 71736.79164544345 65634.9909637366 70105.20753500798 68535.76171173893 63966.96634883585 0.8621131739709746 0.9402953791265447 0.9828694302069018 0.9405353113093318 1.099613222187994 1.121466215143545 1.026076343933592 1.0959595481314215 1.0714242932514217 1.0 15.96503944422185 -6.253433566467224 23.88942162264804 1.0743560495027626 0.9357574579731764 0.705495179362387 0.04344973117357925 183.5020100723271 547570.620298349 0.012920540758513463 0.016363967591009006 5.579129389215983e-07 6.253433566467224 -0.1385985915295862 SIQPQVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 SIQPQVSPR 9 0 A0A2R8YCL1;Q13322-3;Q13322-2;Q13322-4;Q13322 A0A2R8YCL1 GRB10 Growth factor receptor-bound protein 10 1 SIQPQVS(1)PR;SIQPQVS(1)PR;SIQPQVS(1)PR;SIQPQVS(1)PR 125.23 0.0014334 48405000.0 246093.0 211799.0 263511.0 216850.0 227964.0 211524.0 190012.0 165737.0 208851.0 173043.0 True False 242583.66869207047 211308.59242839133 241846.142761876 232797.8723903943 214555.60571446826 202477.61160652706 199849.8916241438 173437.7460726654 185328.00108147084 202953.2519846959 1.1952686952282143 1.0411687931185527 1.191634725715619 1.147051698427325 1.0571676167605693 0.99765640425311 0.9847089892366637 0.8545699286737413 0.9131561050100634 1.0 17.630787931420464 -6.815325951978486 1.3445323500990791 0.920456262740628 1.1410422863948595 0.7413786101960245 0.054713356919352536 0.20791924927763714 0.7848991028033113 0.026334369527337594 0.022657489296301195 1.5299387624138136e-07 6.815325951978486 0.22058602365423152 SIRDT(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 1 SIRDTPAK 8 1 P06748;P06748-3 P06748 NPM1 Nucleophosmin 1 SIRDT(1)PAK 73.666 0.021141999999999998 1208800000.0 476350.0 425900.0 588510.0 775030.0 793840.0 755180.0 687450.0 723740.0 811410.0 1005400.0 True False 627819.3913044853 563563.8460715641 580705.9728743974 596358.807594136 683629.0186758359 707958.4752188965 748631.7182328885 611902.6128906951 854299.4760736529 970201.2520199408 0.6471022274990649 0.5808731383290165 0.5985417681799302 0.6146753638510857 0.704625991001901 0.7297027021403449 0.7716251825837694 0.6306965813708499 0.8805384184930883 1.0 19.887924515731854 -8.962337855199731 0.2337242984803593 1.1143947854298197 0.5491928355199286 0.8011974882433637 0.05735765824388504 2.0078203574823332 0.272981137082573 0.3529343630839382 0.14751209461917494 1.090591591154653e-09 8.962337855199731 -0.5652019499098911 SIRDT(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SIRDTPAK 8 1 P06748;P06748-3 P06748 NPM1 Nucleophosmin 1 SIRDT(1)PAK;S(0.001)IRDT(0.999)PAK 70.685 0.027006 1229210000.0 205049.0 259450.0 215724.0 231940.0 287550.0 218726.0 215751.0 234022.0 215886.0 192808.0 True False 239759.7457976457 285206.48135468445 220867.6782978262 218945.15375962562 231206.64169494703 207255.62351488305 195313.5033780278 227879.17046680563 219042.92433381363 227762.56413271156 1.0526740718371246 1.2522096528053739 0.9697277475728282 0.9612868321593524 1.015121350496514 0.9099635153129044 0.8575311931605384 1.000511964442173 0.9617160974978434 1.0 17.797171114466316 -5.344357637320239 7.55080435782948 0.9554859761332019 1.151739162147677 0.6020053111937123 0.0627264496742078 0.15998542906755067 12.821455275976579 0.016122088052858634 0.03380563771364515 4.5252477663248805e-06 5.344357637320239 0.19625318601447506 SIS(ph)ADDDLQESSR ddPTM_PC-9_AZD4547_30min_R2 2 SISADDDLQESSR 13 0 P18615;P18615-3;A0A0A0MT02;P18615-4;A2ABK4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 1 S(0.002)IS(0.998)ADDDLQESSR;S(0.23)IS(0.77)ADDDLQESSR 158.65 0.00025147 119765100.0 24814.0 22936.0 35134.0 45424.0 37386.0 34666.0 30275.0 38970.0 32301.0 29895.0 True False 32704.335836736696 30349.61346207423 34668.1002038522 34952.19859380413 32195.599229334344 32498.329539895494 32969.41634955362 32948.08194151272 34008.36491620154 28848.385149329824 1.133662618113529 1.0520385562302188 1.2017345173533074 1.211582499778713 1.116027779810832 1.126521618859157 1.1428513651246621 1.14211182951702 1.1788654630115956 1.0 14.816202942709342 -10.689885664647386 6.970349876776647 0.9999997746278002 1.144384026766794 0.502163307642192 0.04332086311815699 1.5861054102718906e-07 1.901404935035246e-08 0.04381394541535523 0.01062642601039631 2.0422755374070757e-11 10.689885664647386 0.14438425213899375 SIS(ph)ADDDLQESSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SISADDDLQESSR 13 0 P18615;P18615-3;A0A0A0MT02;P18615-4;A2ABK4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 1 S(0.013)IS(0.987)ADDDLQESSR 149.35 0.00012115 26214000.0 13410.0 19391.0 9570.0 14465.0 20826.0 16377.0 22693.0 23191.0 15527.0 18988.0 True False 15680.048140427045 21316.010329345485 9798.185094427114 13654.572946162742 16745.294800691896 15518.161289939195 20543.354756907618 22582.260822895605 15754.053000801945 22430.374091074693 0.699054241215991 0.9503189845517277 0.43682664652150965 0.6087536877771492 0.7465454982025932 0.6918369362423631 0.9158721416546529 1.006771475642992 0.7023535558005101 1.0 14.45316606126823 -7.259151367792653 21.885731714048706 0.9068136181520813 0.6882932689224477 0.35916946729234933 0.14223305294412816 42.05085244413367 402244.62803586625 0.05708885104217901 0.041969917565919466 5.506157528722097e-08 7.259151367792653 -0.2185203492296336 SIS(ph)ADDDLQESSR ddPTM_PC-9_Lapatinib_30min_R1 2 SISADDDLQESSR 13 0 P18615;P18615-3;A0A0A0MT02;P18615-4;A2ABK4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 1 S(0.044)IS(0.955)ADDDLQESSR;S(0.066)IS(0.934)ADDDLQESSR 156.96 0.00021732 248970000.0 59763.0 50969.0 55372.0 52521.0 76212.0 69734.0 88226.0 75111.0 78266.0 78856.0 True False 58910.76866080802 50850.984412025995 50819.52790210117 56383.569544919905 71729.35999855693 66751.63937789369 92793.91058686656 78600.93126618663 69450.85890248253 92486.15453098473 0.6369685166342571 0.5498226698893605 0.5494825486021867 0.6096433550605704 0.7755686282158715 0.7217473763116677 1.0033275905722594 0.849867006199871 0.7509324963793915 1.0 16.49694978534535 -6.545754073639012 1.3214723491430158 0.8826202165124868 0.5715485581067773 0.7246635859769384 0.08306223107234484 0.22936959418931277 0.8318779359868674 0.0359932611556844 0.03945060354576666 2.846072286256897e-07 6.545754073639012 -0.3110716584057095 SIS(ph)ADSFDQR ddPTM_PC-9_AZD4547_30min_R2 1 SISADSFDQR 10 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 SIS(1)ADSFDQR 143.0 0.00012795 5041100.0 15717.0 21390.0 25995.0 22812.0 18111.0 27003.0 22325.0 23805.0 19966.0 18003.0 True False 20714.679066091347 28303.899195751987 25650.289315168728 17553.045841886673 15596.600268615912 25314.498141285367 24311.88175074435 20126.48423448062 21021.361998603137 17372.720449686727 1.1923681801064658 1.6292151409287412 1.4764693525953367 1.010379801639138 0.8977638426742288 1.4571407060050776 1.3994285938782116 1.1585107981659575 1.210021312406613 1.0 14.084536067504441 -1.5228787469838363 0.028721593595720348 6.013093513204301e-09 3.0406136786866194 0.155481828743824 0.20898079982625692 3114.334075777435 6.889728025426411 237.2830711702788 553.1646464518675 0.029999999882326475 1.5228787469838363 3.040613672673526 SIS(ph)ADSFDQR ddPTM_PC-9_Lapatinib_30min_R1 1 SISADSFDQR 10 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 SIS(1)ADSFDQR 101.35 0.0036361999999999996 3152000.0 19842.0 27949.0 26541.0 18418.0 26066.0 33351.0 33419.0 35801.0 29822.0 27268.0 True False 19559.049441422852 27884.285807681452 24358.90143122276 19772.52116064688 24532.84912772774 31924.65547497822 35149.27229957715 37464.44515797613 26463.132320417997 31981.23746767391 0.6115788815611906 0.8718951490187462 0.7616622544966974 0.6182537864781689 0.7671013090886531 0.9982307753803185 1.0990591697743226 1.1714507669018297 0.8274580477746204 1.0 14.964938142443254 -6.7633257710459285 3.9453598473722993 1.0397066401312651 0.7261908514222837 0.6523354117293025 0.1072591606615454 0.13319548612476034 4.604594175678959 0.03787964375035227 0.03533470354404982 1.7245437995637023e-07 6.7633257710459285 -0.31351578870898145 SIS(ph)CGPSSR ddPTM_PC-9_AZD4547_30min_R2 2 SISCGPSSR 9 0 Q5VU43-13;Q5VU43-2 Q5VU43-13 1 S(0.041)IS(0.958)CGPS(0.001)SR;S(0.001)IS(0.996)CGPS(0.003)SR 96.171 0.0051903999999999995 71251000.0 19494.1 19749.4 25447.0 37748.0 30252.0 25429.0 29942.0 40597.0 28588.0 26170.9 True False 25692.81829753078 26133.007329433596 25109.556153225567 29045.781800786346 26052.031987530707 23838.92061010797 32606.77999466012 34323.66647625331 30099.10331644127 25254.66475680199 1.017349410295014 1.0347794192118522 0.994254186108832 1.150115516499314 1.031573067328639 0.943941281330503 1.29111909853715 1.35910204339611 1.1918235148353928 1.0 14.624262270381745 -7.267952386390733 24.986692353554847 1.2404363411925716 1.0330345822325528 0.43018161785091824 0.10011185439818748 436.29174742052203 1673794.3074602385 0.040006816736819405 0.02771325326765924 5.39569774673961e-08 7.267952386390733 -0.20740175896001878 SIS(ph)CGPSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SISCGPSSR 9 0 Q5VU43-13;Q5VU43-2 Q5VU43-13 1 S(0.054)IS(0.946)CGPSSR;S(0.086)IS(0.914)CGPSSR;S(0.02)IS(0.979)CGPS(0.001)SR 91.469 0.007776899999999999 62287000.0 46151.0 40272.0 50103.0 44894.0 59960.0 47133.0 52279.0 58263.0 48631.0 42296.0 True False 53963.45277620053 44269.938011624065 51297.645536685624 42378.73472831181 48211.26842646144 44661.26250709557 47326.75465281685 56733.65798475126 49342.136374186906 49963.929985048235 1.0800482026203535 0.8860379482733223 1.026693567780527 0.8481865766162449 0.964921463161299 0.8938700882909032 0.9472184167054001 1.135492304182815 0.9875551500643084 1.0 15.60859933821974 -7.652573672920577 12.265625292846014 1.0460864748024121 0.9444433643379391 0.2415236072392365 0.07372358499541615 0.5452574727544739 57.74766951833095 0.03234225558123873 0.018663282752578864 2.225493484130506e-08 7.652573672920577 -0.10164311046447305 SIS(ph)CGPSSR ddPTM_PC-9_Lapatinib_30min_R1 3 SISCGPSSR 9 0 Q5VU43-13;Q5VU43-2 Q5VU43-13 1 S(0.118)IS(0.866)CGPS(0.016)SR;S(0.008)IS(0.992)CGPSSR;S(0.021)IS(0.946)CGPS(0.026)S(0.007)R 93.345 0.0063279 75439300.0 39697.4 43585.0 53633.0 30635.8 57960.0 53196.0 51768.0 43916.0 58691.0 43291.5 True False 39131.307796388406 43484.0816103544 49223.50176936702 32888.858930032904 54550.906753744326 50920.93108593264 54448.29373723066 45956.497683240115 52080.60153637093 50774.37809270224 0.7706900461674531 0.856417808426182 0.9694555328574646 0.6477451849825807 1.0743786295943798 1.002886357228499 1.0723576690160677 0.9051119759524028 1.025726035310247 1.0 15.631813043404819 -6.286511943498088 24.99712126909063 1.0110869055246499 0.8256284652639638 0.5626455197703213 0.08700002352155506 606.6844911849837 604857.0973180014 0.026393112297415332 0.029938531464097865 5.169970398785782e-07 6.286511943498088 -0.18545844026068603 SIS(ph)ESSR ddPTM_PC-9_Lapatinib_30min_R1 1 SISESSR 7 0 Q9H307 Q9H307 PNN Pinin 1 S(0.343)IS(0.653)ES(0.004)SR 109.48 0.0096065 86853000.0 201900.0 197100.0 199410.0 161220.0 206620.0 238120.0 246320.0 218050.0 219790.0 263350.0 True False 199020.86897607413 196643.62705978798 183015.27954486027 173076.65661415376 194467.01783054942 227936.16268483107 259073.24434698356 228181.39903066074 195034.93570869416 308869.69660818274 0.6443522014674765 0.6366556163301466 0.5925323252964653 0.5603549280320319 0.6296086018345818 0.7379686812525993 0.8387784466782167 0.7387626612011754 0.6314472991376234 1.0 18.236638808666676 -6.807251212328271 3.382374481671915 0.7812564262911892 0.6078983432756766 0.4980069200351057 0.08962258289721882 0.22089726867968762 5.180626029245244 0.03205774665464536 0.02905930728502792 1.5586506596223292e-07 6.807251212328271 -0.1733580830155126 SIS(ph)GTSTSEKPNSMDTANTSPFK ddPTM_PC-9_AZD4547_30min_R2 2 SISGTSTSEKPNSMDTANTSPFK 23 1 Q9UJF2-2;Q9UJF2 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 S(0.149)IS(0.524)GT(0.23)S(0.031)T(0.015)S(0.041)EKPNS(0.009)MDT(0.001)ANTSPFK;S(0.236)IS(0.596)GT(0.13)S(0.03)T(0.007)S(0.002)EKPNSMDTANTSPFK 93.06200000000001 6.1271e-06 77233000.0 46128.0 41176.0 59148.0 62094.0 61659.0 49602.0 55393.0 67126.0 54670.0 55219.0 True False 60795.74447799585 54485.33675943352 58363.658873383385 47779.18764273679 53098.71216181263 46500.37909876813 60322.869689540006 56753.219102026735 57559.74458898292 53285.79961735554 1.1409370773183307 1.0225113848472172 1.0952947932186787 0.8966589219987007 0.9964889809876857 0.8726598724742163 1.1320627657409208 1.0650721113236674 1.0802079541325929 1.0 15.701463493186958 -10.350890611545593 13.789554412018452 1.0000081755313242 1.0290126593148234 0.010986844910267024 0.08632770434118935 0.0 0.0 0.08554625583699094 0.02074801462894265 4.457685127485255e-11 10.350890611545593 0.02900448378349929 SIS(ph)GTSTSEKPNSMDTANTSPFK ddPTM_PC-9_Lapatinib_30min_R1 1 SISGTSTSEKPNSMDTANTSPFK 23 1 Q9UJF2-2;Q9UJF2 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 S(0.368)IS(0.436)GT(0.101)S(0.031)T(0.031)S(0.031)EKPNSMDTANTSPFK 61.976000000000006 0.0057993 19487000.0 36017.0 45937.0 46961.0 40499.0 44655.0 43474.0 43817.0 39677.0 48504.0 41063.0 True False 35503.39097529114 45830.63569886085 43100.04785470225 43477.431560703524 42028.480695107864 41614.718362843756 46085.62986177242 41520.53826800977 43040.96875023657 48160.68483699182 0.7371861736488697 0.9516192689946702 0.8949218226564225 0.9027577516362241 0.872671990387191 0.8640807020019747 0.9569139230008297 0.8621251630566139 0.8936951145091931 1.0 15.55556828667836 -14.522878745280336 0.15282813439231452 1.3963169209906379 0.8530794909330341 0.31489794097918344 0.05586071927111502 177.5874894551354 1.5914859554884158 21.52001307292888 0.2599838643374573 3.0000000000000132e-15 14.522878745280336 -0.5432374300576037 SIS(ph)LGDSEGPIVATLAQPLR ddPTM_PC-9_AZD4547_30min_R2 3 SISLGDSEGPIVATLAQPLR 20 0 O43379;O43379-4 O43379 WDR62 WD repeat-containing protein 62 1 S(0.001)IS(0.998)LGDS(0.001)EGPIVATLAQPLR;S(0.001)IS(0.999)LGDSEGPIVATLAQPLR;S(0.004)IS(0.969)LGDS(0.027)EGPIVATLAQPLR 205.15 4.6462e-21 125857000.0 165192.9 155226.06 197504.31 269043.8 260537.28 243355.0 202437.94 229857.42 195752.5 209298.3 True False 217720.80597422685 205399.84828395266 194885.2738023765 207019.9085952739 224366.17587281045 228137.97337971744 220454.52448574646 194338.2373370468 206099.5775133508 201970.8302224442 1.077981437886036 1.0169777886129985 0.9649179219976276 1.024999047472691 1.1108840599689604 1.1295590216094749 1.091516652394531 0.9622094295646995 1.020442294990615 1.0 17.623787420224687 -7.762861179751927 24.999102160510258 0.9934943971388296 1.0576094471916846 0.28304299621939566 0.04757415394575671 60.05661722161527 1055877.6638923676 0.028257312306976718 0.01471429794577509 1.7263896363684768e-08 7.762861179751927 0.064115050052855 SIS(ph)LGDSEGPIVATLAQPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SISLGDSEGPIVATLAQPLR 20 0 O43379;O43379-4 O43379 WDR62 WD repeat-containing protein 62 1 S(0.008)IS(0.935)LGDS(0.057)EGPIVATLAQPLR;SIS(0.999)LGDS(0.001)EGPIVATLAQPLR 261.66 1.3770999999999995e-157 1531800.0 5729.5 9721.9 8832.4 10286.099999999999 11464.800000000001 7411.09 11134.05 10350.5 7021.200000000001 6084.86 True False 6699.391187216765 10687.025982201225 9042.997913063535 9709.80316498614 9218.354740755432 7022.439393921688 10079.35218045861 10078.81034226126 7123.871767194606 7187.996950274743 0.9320247676177293 1.4867877735803354 1.2580692473329291 1.3508357379888716 1.2824650322650852 0.9769674976911715 1.4022476985154193 1.402172317543349 0.9910788522138027 1.0 12.811374081403036 -8.280570067497163 23.597082070811442 0.9955391708616317 1.2677361014581843 0.2810031065797003 0.169898303783914 568.8867256060653 701690.0997474963 0.1569784711774702 0.04086618826661939 5.241190347219846e-09 8.280570067497163 0.2721969305965526 SIS(ph)LGDSEGPIVATLAQPLR ddPTM_PC-9_Lapatinib_30min_R1 5 SISLGDSEGPIVATLAQPLR 20 0 O43379;O43379-4 O43379 WDR62 WD repeat-containing protein 62 1 S(0.002)IS(0.997)LGDS(0.001)EGPIVATLAQPLR;S(0.022)IS(0.944)LGDS(0.034)EGPIVATLAQPLR;S(0.057)IS(0.942)LGDS(0.001)EGPIVATLAQPLR;S(0.003)IS(0.995)LGDS(0.002)EGPIVATLAQPLR;S(0.018)IS(0.982)LGDSEGPIVATLAQPLR 218.36 1.2990999999999999e-28 216347800.0 182818.82 198356.89 218094.44 175589.59000000003 212699.01 234692.3 201853.91 168324.1 219400.2 186532.63 True False 180211.79010193486 197897.60680821602 200163.55701208388 188503.03419830117 200188.47241414327 224655.05742347223 212304.9177810328 176145.0521833377 194689.03908947002 218774.546556394 0.823732892781845 0.9045732692546274 0.9149307365173183 0.8616314702300633 0.9150446227186683 1.0268793191879038 0.9704278725418658 0.8051441767606745 0.8899071768355128 1.0 17.739085371191706 -3.470432950986438 0.9019362642021386 0.9228486228152392 1.1019385130054174e-16 0.19126265162672407 0.061427039290153855 38.592140286844035 3.7911296954506857 0.02213078129621549 59.50161210265443 0.0003385065285212835 3.470432950986438 -0.922848622815239 SIS(ph)LMTISHPGLDNSR ddPTM_PC-9_AZD4547_30min_R2 1 SISLMTISHPGLDNSR 16 0 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36;H0YMW2 Q12802-2 AKAP13 A-kinase anchor protein 13 1 S(0.146)IS(0.81)LMT(0.041)IS(0.003)HPGLDNSR 57.413999999999994 0.022548 4600400.0 9808.8 11309.0 19954.0 33429.0 25790.0 25767.0 16399.0 25636.0 16426.0 22123.0 True False 12927.794364285603 14964.413090451573 19689.396922288004 25722.460522901525 22209.503667804336 24155.785416675917 17858.4792309275 21674.545256674883 17294.244825656384 21348.480503717135 0.6055603986445149 0.7009591660561515 0.9222856361538116 1.20488484032495 1.040331824269052 1.1314990503642628 0.8365222633909721 1.0152734407913 0.8100925413705748 1.0 14.381845768001076 -5.26418471908598 3.091609643498517 1.0087373849734675 0.6299204995967287 0.6050469761885411 0.11264886914024891 0.16921847048990316 3.282949451140573 0.031157962910019585 0.09030603086204743 5.442711080044237e-06 5.26418471908598 -0.37881688537673885 SIS(ph)LTRPGSSSLSSGPNSILCR ddPTM_PC-9_AZD4547_30min_R2 1 SISLTRPGSSSLSSGPNSILCR 22 1 A0A087WZ32;A0A087X038;A8K727;Q9HB19 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 S(0.331)IS(0.355)LT(0.314)RPGSSSLSSGPNSILCR 60.86 0.0032768999999999997 44388000.0 5169.3 3747.5 4669.4 18013.0 12535.0 4836.7 11911.0 10371.0 4361.7 10369.0 True False 6813.029871880505 4958.806088643315 4607.480705068241 13860.381148075783 10794.731619849837 4534.260384400061 12971.05592533554 8768.400251871399 4592.2505574129655 10005.984466077967 0.6808955075812745 0.4955840282837269 0.4604725022998391 1.3852091410960004 1.0788275413024937 0.45315484945754164 1.2963298083571568 0.8763155970907016 0.45895039843220786 1.0 13.288575497263572 -5.695620469822166 24.999998930614083 0.9313053818017457 0.5406418196509416 0.27321352196122883 0.29131695267594393 78.94798610065554 29985.456668695253 0.07978214728253202 0.13818670045624276 2.015484813718056e-06 5.695620469822166 -0.3906635621508041 SIS(ph)LTRPGSSSLSSGPNSILCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SISLTRPGSSSLSSGPNSILCR 22 1 A0A087WZ32;A0A087X038;A8K727;Q9HB19 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 S(0.204)IS(0.757)LT(0.037)RPGS(0.001)S(0.001)SLSSGPNSILCR 63.372 0.0019297000000000001 35250000.0 5079.7 3338.7 2497.4 4561.6 13254.0 5023.1 8039.8 11682.0 3084.4 2782.3 True False 5939.592881351772 3670.144071300388 2556.947487442243 4306.028340906737 10656.973844635098 4759.679793337828 7278.211940888638 11375.359878102132 3129.5035148884876 3286.7089653253183 1.8071551037874969 1.1166623239295899 0.7779658967124753 1.310133749697709 3.242445241445426 1.4481597986168866 2.2144376084629207 3.461018300711088 0.9521693426173892 1.0 11.6824279975844 -6.034761319774471 24.77994355242583 2.165040409820909 1.192508989767042 0.17805528582884234 0.8210043653530937 760.7133843301698 542280.7234947382 0.2315043859614896 0.2990308935180746 9.230785947227808e-07 6.034761319774471 -0.9725314200538671 SIS(ph)LTRPGSSSLSSGPNSILCR ddPTM_PC-9_Lapatinib_30min_R1 1 SISLTRPGSSSLSSGPNSILCR 22 1 A0A087WZ32;A0A087X038;A8K727;Q9HB19 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 S(0.201)IS(0.641)LT(0.153)RPGS(0.001)S(0.001)S(0.001)LS(0.001)SGPNSILCR 57.693999999999996 0.0049753 36629000.0 2461.3 3611.7 3298.3 9765.6 8519.9 2314.1 10736.0 8581.3 2472.9 7700.1 True False 2426.2014106528595 3603.337330552186 3027.126505806187 10483.794801086615 8018.776232767878 2215.131337430573 11291.857548348551 8980.018525575835 2194.375961208561 9031.052025261686 0.2686510280160364 0.39899419474862063 0.33519090548240665 1.160860857822689 0.8879116420033605 0.2452794349134963 1.2503368950552973 0.9943491079950486 0.2429812113882686 1.0 13.140678341385188 -5.731138963050949 24.48887504593645 0.8217930792433392 0.340749510884313 0.3278040181967967 0.322573175422797 199.53735733844763 161264.69825458794 0.08744575598473027 0.15143332719036062 1.8572101005994295e-06 5.731138963050949 -0.48104356835902623 SIS(ph)NEGLTLNNSHVSK ddPTM_PC-9_AZD4547_30min_R2 2 SISNEGLTLNNSHVSK 16 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 S(0.036)IS(0.964)NEGLTLNNSHVSK;S(0.015)IS(0.985)NEGLTLNNSHVSK 142.55 2.6684e-05 24747000.0 8921.8 8554.3 26748.0 69819.0 43091.0 33759.0 17298.3 57031.0 26408.6 39727.0 True False 11758.746815031735 11319.310186546101 26393.304043167285 53723.30824279703 37108.5584548025 31648.044393276756 18837.81518875255 48218.1693920044 27804.504681774557 38336.16982195768 0.30672722052417234 0.29526450449055497 0.6884700314544746 1.401373911173205 0.9679777251390397 0.8255400719544448 0.4913849055928085 1.257772219184678 0.7252812372990132 1.0 15.226418583668208 -5.4189817138107115 4.014574282959797 0.9457625387495693 0.3083217496733967 0.5302249694276103 0.2424475146801517 0.17852520530317734 4.984699186507669 0.06629377295716575 0.14617309267752454 3.810818687012109e-06 5.4189817138107115 -0.6374407890761726 SIS(ph)NEGLTLNNSHVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SISNEGLTLNNSHVSK 16 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 S(0.014)IS(0.985)NEGLT(0.001)LNNSHVSK;S(0.037)IS(0.958)NEGLT(0.005)LNNSHVSK 199.01 4.3835e-12 10744000.0 10854.7 12230.800000000001 23278.0 24548.0 30152.0 36590.0 26035.0 26983.0 29837.0 18252.2 True False 12692.186319902574 13444.99299345876 23833.03580230661 23172.655145689787 24243.932047943064 34671.155986986334 23568.776322922895 26274.724840851723 30273.309678941707 21561.1793756643 0.5886591869008803 0.6235740985780153 1.1053679108669963 1.0747396857077463 1.1244251358210366 1.6080361553004388 1.093111648128327 1.2186125992025982 1.4040655731991465 1.0 14.396148473821999 -5.289398135567515 1.2360108795201712 1.2553913979192837 0.47100050145046035 0.6689213373189005 0.16891979621675998 0.40148195150299365 0.9236494181443958 0.05329469529674337 0.3199241529562746 5.135726226183115e-06 5.289398135567515 -0.7843908964688233 SIS(ph)NEGLTLNNSHVSK ddPTM_PC-9_Lapatinib_30min_R1 3 SISNEGLTLNNSHVSK 16 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 S(0.002)IS(0.998)NEGLTLNNSHVSK;S(0.054)IS(0.946)NEGLTLNNSHVSK;S(0.026)IS(0.971)NEGLT(0.003)LNNSHVSK 182.77 1.7363e-07 20941500.0 79515.0 44669.8 157325.0 68503.1 116321.0 163274.0 86446.0 82623.0 209334.0 78968.1 True False 78381.1015187349 44566.36982260432 144390.3457920622 73541.04649364259 109479.227475885 156291.15163028365 90921.75089647352 86461.96621009061 185756.6005352554 92617.63086662113 0.8462870490782873 0.48118667477884913 1.5589941617055514 0.7940285861938018 1.1820560130019553 1.6874881182758703 0.9816894477403568 0.9335367942482214 2.0056289369219984 1.0 16.498999233322955 -5.253849897611342 24.996801667685414 1.2503237569873416 0.663736834599111 0.2977704114527533 0.3703473291204556 713.3703548845316 2349550.1315289936 0.09160565343027727 0.2327171532194672 5.573783587165068e-06 5.253849897611342 -0.5865869223882305 SIS(ph)NPPGSNLR ddPTM_PC-9_AZD4547_30min_R2 1 SISNPPGSNLR 11 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 S(0.005)IS(0.994)NPPGS(0.001)NLR 93.649 0.0069867 9036800.0 43534.0 28895.0 47692.0 65986.0 49678.0 47518.0 39609.0 62563.0 39599.0 52746.0 True False 57376.9064365477 38234.74367747797 47059.57291860075 50773.94717353736 42781.0672046989 44546.69194821307 43134.12426719964 52895.32590471799 41692.122297039255 50899.378594632886 1.127261432669 0.7511829168285692 0.9245608535496537 0.997535698380633 0.8405027406210804 0.87519127302097 0.8474391133676421 1.039213588951272 0.8191086698538891 1.0 15.635360422806924 -11.107795785445099 8.970287439661877 1.0000170059058493 0.9100475013661161 0.05429710004654431 0.1073357629539017 3.392229325251117e-05 1.5697537886859775e-06 0.09657475968799975 0.02341839523968103 7.80196889548619e-12 11.107795785445099 -0.08996950453973318 SIS(ph)NPPGSNLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SISNPPGSNLR 11 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 S(0.01)IS(0.673)NPPGS(0.317)NLR 100.02 0.00432 9541400.0 50880.0 51648.0 50774.0 81609.0 63071.0 65845.0 61417.0 66455.0 47303.0 43576.0 True False 59492.979074193034 56775.27211025924 51984.644721467266 77036.71230994782 50712.69030896184 62391.972286502234 55599.13713942603 64710.62666489279 47994.71688651603 51475.98385257382 1.1557424379605783 1.1029468086100593 1.009881518153208 1.496556385023731 0.985171851288981 1.212059830953238 1.0800985814794881 1.257103251299144 0.9323710455728622 1.0 15.651611878679242 -8.27341337914362 24.85844470133427 0.9661854862315976 1.159513232906295 0.24425083755144483 0.13801272714968585 1107.4177877869267 2299011.5880470127 0.12241074297779843 0.032589995858864004 5.3282748717621654e-09 8.27341337914362 0.19332774667469732 SIS(ph)NPPGSNLR ddPTM_PC-9_Lapatinib_30min_R1 1 SISNPPGSNLR 11 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 S(0.002)IS(0.836)NPPGS(0.162)NLR 88.803 0.0096288 9004300.0 71034.0 68894.0 57805.0 57685.0 54084.0 44353.0 51031.0 44719.0 49176.0 57787.0 True False 70021.04213395965 68734.48017583459 53052.49603375274 61927.34733151888 50902.88545323516 42456.125581892826 53673.135483399295 46796.80799473574 43637.28103376283 67775.40595366256 1.0331334965641137 1.0141507706029491 0.7827691370823253 0.9137141483720225 0.7510524612429029 0.6264237740002576 0.7919264330204845 0.6904688704739047 0.6438512675762835 1.0 16.04847422893419 -5.258562090289244 0.8900036305303128 0.7344245307636953 1.1140385496539171 0.4433972822316169 0.10971968290912945 1.0305241166913095 1.0290548464770457 0.040183663554644505 0.330947154162479 5.513633693322067e-06 5.258562090289244 0.37961401889022184 SIS(ph)PEVSASR ddPTM_PC-9_AZD4547_30min_R2 4 SISPEVSASR 10 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 S(0.002)IS(0.993)PEVS(0.005)ASR;S(0.168)IS(0.542)PEVS(0.026)AS(0.264)R;S(0.003)IS(0.996)PEVS(0.001)ASR;S(0.001)IS(0.975)PEVS(0.023)ASR 158.08 0.00033883 132913000.0 533624.0 537560.0 601253.0 637170.0 566480.0 674610.0 520951.0 636600.0 480782.0 493240.0 True False 703305.3319312786 711315.7574412546 593279.9923682685 490280.3006783677 487834.03015656443 632426.5300556411 567314.6297841874 538228.0976127029 506195.1549840936 475971.817730572 1.477619694553829 1.4944493159969001 1.246460337078402 1.0300616179672535 1.0249220898887488 1.3287058319356875 1.1919080261708284 1.1307982480537777 1.0634981654956508 1.0 18.860516628591853 -5.393824723998875 3.353049770640834 1.1247057692175824 1.4885916417133158 0.7178051395373849 0.09284991258196068 0.13690352225984362 2.818663097976098 0.026647649660143487 0.06267529409571371 4.038083322450139e-06 5.393824723998875 0.36388587249573345 SIS(ph)PEVSASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SISPEVSASR 10 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 S(0.001)IS(0.976)PEVS(0.02)AS(0.003)R;S(0.034)IS(0.962)PEVS(0.004)ASR;S(0.044)IS(0.923)PEVS(0.032)ASR;S(0.208)IS(0.713)PEVS(0.078)AS(0.002)R 131.42 0.00018045 101442000.0 469121.0 602350.0 639050.0 566343.0 585290.0 534636.0 586790.0 519902.0 486293.0 464845.0 True False 548533.9197379026 662147.3272075336 654287.3756106226 534612.6378187797 470606.6260394195 506598.7469871115 531205.003208294 506255.12338170246 493404.11514902976 549117.7187890057 0.9989368417169445 1.2058385744095044 1.191524791903551 0.9735847515497866 0.8570232027428831 0.9225685670903806 0.9673790974725505 0.9219427930647912 0.8985397816649522 1.0 19.06675593898178 -5.876632010014322 5.1452964785632656 0.9250423918679306 1.1382824795415596 0.6754044617145786 0.06324977379834762 0.11187013316823849 4.5755341655536155 0.017759597175784462 0.026910641367932645 1.3285196732059385e-06 5.876632010014322 0.213240087673629 SIS(ph)PEVSASR ddPTM_PC-9_Lapatinib_30min_R1 3 SISPEVSASR 10 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 S(0.013)IS(0.905)PEVS(0.081)ASR;S(0.001)IS(0.985)PEVS(0.015)ASR;S(0.011)IS(0.975)PEVS(0.014)AS(0.001)R 147.28 0.00014633 92674000.0 232806.0 252647.0 287155.0 235192.0 269706.0 263098.0 257954.0 263212.0 268959.0 216957.0 True False 229486.14374860804 252062.011394086 263546.22435035545 252488.8042575118 253842.42334239747 251845.91185139338 271309.5959413845 275441.7904226477 238666.00515617008 254457.7283729698 0.9018635245074583 0.9905850099574406 1.0357171151196642 0.9922622742565238 0.997581896865516 0.9897357547822317 1.0662265896821737 1.0824658075188058 0.937939698991366 1.0 17.957066483853858 -4.7853232238985495 3.1955711752066285 1.015516581384888 0.885816697618884 0.4168925420918086 0.0390871452069138 0.32631949617315553 5.101854581037745 0.010032071825247423 0.10659128161489845 1.6393692176464024e-05 4.7853232238985495 -0.12969988376600405 SIS(ph)PEWK ddPTM_PC-9_AZD4547_30min_R2 1 SISPEWK 7 0 F5H6E2;O00159-2;O00159-3;O00159 F5H6E2 MYO1C Unconventional myosin-Ic 1 S(0.06)IS(0.94)PEWK 96.66799999999999 0.012731000000000001 4253300.0 31972.0 36045.0 45818.0 52659.0 48702.0 42580.0 41219.0 54341.0 42644.0 43375.0 True False 42138.43094108751 47695.8413516073 45210.42338305061 40519.28112343989 41940.567957712585 39917.465868826825 44887.41114821637 45943.84708195388 44898.07478054853 41856.454452322476 1.0067367504595073 1.1395098312958234 1.0801302684284582 0.968053354103231 1.0020095707219043 0.9536752787863506 1.072413125658944 1.097652624502327 1.072667892396158 1.0 15.353162489502113 -10.509459203208745 17.77883937679519 1.0000000000067528 1.0438820616066358 0.05082829407859846 0.056579906432740974 0.0 0.0 0.059629965578821435 0.014462390972554482 3.094145959941335e-11 10.509459203208745 0.04388206159988295 SIS(ph)PEWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SISPEWK 7 0 F5H6E2;O00159-2;O00159-3;O00159 F5H6E2 MYO1C Unconventional myosin-Ic 1 S(0.289)IS(0.711)PEWK;S(0.002)IS(0.998)PEWK 75.378 0.032806 9850400.0 81861.0 84801.0 93192.0 100334.0 116285.0 95398.0 100473.0 99299.0 82153.0 83341.0 True False 95718.45047155113 93219.48284971516 95414.05071262807 94712.61126721685 93499.7890088572 90395.16094141897 90955.47007847276 96692.50646598713 83354.33220679335 98450.06357300695 0.972253820847661 0.9468707227455168 0.9691619004580176 0.9620370757504028 0.9497179139912002 0.9181828600281731 0.923874162976274 0.9821477300955069 0.8466661084985572 1.0 16.587104517280466 -6.545045388815407 5.250860574331572 0.9323903184336888 0.9613626937737789 0.10539734661519684 0.03881244221345429 0.40517586224246704 31.735287567287177 0.012021907300002362 0.012362980053652255 2.8507203185651903e-07 6.545045388815407 0.028972375340090117 SIS(ph)SPNVNR ddPTM_PC-9_AZD4547_30min_R2 1 SISSPNVNR 9 0 Q9NQT8 Q9NQT8 KIF13B Kinesin-like protein KIF13B 1 S(0.203)IS(0.613)S(0.184)PNVNR 92.943 0.0066384 26286000.0 46752.0 54430.0 73299.0 94097.0 83004.0 57028.0 72412.0 73749.0 75320.0 58896.0 True False 61618.16349798956 72023.43306333716 72327.00736728412 72404.39043415796 71480.32735333197 53462.03014484398 78856.52771936824 62352.78663342626 79301.2614311724 56834.06896654722 1.084176526833901 1.2672580790534365 1.2725994932697169 1.2739610545353617 1.2577020905437126 0.9406687065870994 1.3874869273530908 1.0971022797985375 1.3953120526677314 1.0 15.794468386645827 SIS(ph)SPNVNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SISSPNVNR 9 0 Q9NQT8 Q9NQT8 KIF13B Kinesin-like protein KIF13B 1 S(0.197)IS(0.774)S(0.03)PNVNR 67.385 0.045893 78254000.0 103230.0 87665.0 95636.0 103930.0 97036.0 116110.0 109430.0 101090.0 82435.0 90468.0 True False 120704.80011456273 96367.80184219845 97916.32494154954 98107.13904560631 78022.49237875447 110020.98720002678 99063.99819540823 98436.4946137086 83640.455923302 106869.13225570599 1.1294636492954029 0.9017365427055121 0.9162264432658155 0.9180119364201925 0.7300750996281123 1.0294926596463734 0.9269654960646411 0.9210937951491867 0.7826437265643301 1.0 16.705485684161765 -4.761414928998697 9.515477684595238 0.9005668241029812 1.1306936684904376 0.39340005384141297 0.08435041059545484 0.07827405473662515 121.72010325200345 0.02033242107424007 0.11567265350727729 1.7321482963056543e-05 4.761414928998697 0.23012684438745645 SIS(ph)SPNVNR ddPTM_PC-9_Lapatinib_30min_R1 1 SISSPNVNR 9 0 Q9NQT8 Q9NQT8 KIF13B Kinesin-like protein KIF13B 1 S(0.051)IS(0.915)S(0.034)PNVNR 74.962 0.026666000000000002 71927000.0 115530.0 123270.0 156920.0 128780.0 147940.0 143740.0 150200.0 153020.0 159260.0 136890.0 True False 113882.52101439278 122984.57588868642 144018.6433287166 138250.91079748663 139238.4600612309 137592.57527430556 157976.62106575558 160129.86782697463 141322.46171785163 160551.2541055407 0.7093219025217359 0.7660144205902043 0.8970259630238943 0.8611014069476243 0.8672523976032008 0.8570009374318378 0.9839637936549992 0.997375378467682 0.880232686472516 1.0 17.292674408792166 -2.932753441080659 0.2865077693382214 0.9798185155241547 5.844731511320015e-14 0.7476544885485045 0.04560254944455228 12.534592847454686 0.36196651509947075 0.05325178096360132 5.26705103454458 0.001167472229663804 2.932753441080659 -0.9798185155240963 SIS(ph)SSNPDLAVAPGSVDDEVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SISSSNPDLAVAPGSVDDEVSR 22 0 Q96HP0;K7ESB7;K7EKT0;K7EP20 Q96HP0 DOCK6 Dedicator of cytokinesis protein 6 1 S(0.007)IS(0.714)S(0.214)S(0.064)NPDLAVAPGSVDDEVSR 235.85 1.9605e-51 7111400.0 9984.3 10527.0 10748.0 12406.0 16620.0 14004.0 14755.0 11768.0 11408.0 9291.9 True False 11674.444791086189 11572.050989480695 11004.273082016984 11710.932040794667 13363.430307668272 13269.605587366954 13357.299583050806 11459.102469226656 11574.820418184374 10976.447915360073 1.0635904147779323 1.054261914119517 1.002534988265008 1.0669145547902414 1.217464011191447 1.2089161894348273 1.2169054767124663 1.0439718347491243 1.054514220578313 1.0 13.422123639358281 -6.017324021799041 23.804125817245293 1.135431250190036 1.0404061034841188 0.20367636291076063 0.07361059080789857 571.9227957873727 785854.8532429937 0.022850110317940462 0.030236178454085973 9.608950988015075e-07 6.017324021799041 -0.09502514670591733 SIS(ph)TVNLSENSSVVIPPPDYLECLSMGAAADRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SISTVNLSENSSVVIPPPDYLECLSMGAAADRR 33 1 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 S(0.221)IS(0.557)T(0.221)VNLSENSSVVIPPPDYLECLSMGAAADRR;S(0.208)IS(0.554)T(0.235)VNLS(0.002)ENSSVVIPPPDYLECLSMGAAADRR 59.005 0.000264 16265400.0 6553.8 8193.0 10556.0 9573.0 14123.400000000001 13460.4 12787.8 12817.3 11061.3 8263.3 True False 7663.2288965496455 9006.346894349317 10807.695073852936 9036.655846084748 11356.021155675213 12754.512928320053 11576.447008345438 12480.859456051909 11223.050586576323 9761.370877753194 0.7850566270373609 0.9226518495343081 1.1071902921427137 0.9257568387940142 1.163363353149129 1.3066313213637264 1.1859447974391508 1.278596993430155 1.1497412327764733 1.0 13.252868057414636 -5.052087591925815 0.6838101228167531 1.1997071709820977 0.639346540834178 0.5917731972972096 0.102319659824067 1.5603390594896769 0.7047271648345937 0.04760899619338911 0.6419371366992402 8.869771014807073e-06 5.052087591925815 -0.5603606301479197 SIS(ph)TVNLSENSSVVIPPPDYLECLSMGAAADRR ddPTM_PC-9_Lapatinib_30min_R1 1 SISTVNLSENSSVVIPPPDYLECLSMGAAADRR 33 1 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 S(0.097)IS(0.642)T(0.259)VNLS(0.002)ENSSVVIPPPDYLECLSMGAAADRR 54.051 0.00056275 4850700.0 5570.8 5958.9 6272.2 5808.1 5121.6 4553.8 5182.0 4984.9 6385.6 5170.6 True False 5491.359370440396 5945.102533163726 5756.523927392161 6235.247049253617 4820.3575574530205 4359.0445894262775 5450.2986042792645 5216.516652272148 5666.3864846509705 6064.331320608578 0.9055177034570924 0.980339334851367 0.9492429788309246 1.0281837715667368 0.7948704156502584 0.7188005336405056 0.8987468388736233 0.860196512440658 0.9343794369207268 1.0 12.566132860984622 -6.26220632313756 24.99999313612084 0.8549362552794906 0.9656738339078564 0.27050631174730466 0.07710635293848957 86.4034049604776 2816495.4300625464 0.02379092256719591 0.028609558340536842 5.467561501409937e-07 6.26220632313756 0.11073757862836586 SIS(ph)VGENLGLVAEPQAHAPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SISVGENLGLVAEPQAHAPIR 21 0 O60336-4;O60336-3;O60336-6;O60336 O60336-4 MAPKBP1 Mitogen-activated protein kinase-binding protein 1 1 S(0.208)IS(0.792)VGENLGLVAEPQAHAPIR 84.291 0.00026511 3122300.0 7215.1 7099.8 7749.3 9253.5 9205.8 6725.0 9195.7 7712.1 5010.0 5646.0 True False 8436.47392527929 7804.621223056422 7934.0727013839105 8735.056395251777 7401.989574388242 6372.329161314105 8324.616724897343 7509.665546645387 5083.261772011195 6669.575106288589 1.2649192476031543 1.170182672610977 1.1895919267635289 1.3096870874151627 1.1098142619923532 0.955432551513781 1.2481479842768775 1.125958614599706 0.762156762762639 1.0 12.70337914028849 -7.494211035812331 0.613351327863776 0.9298329147371703 1.2243614593370014 0.41875205440357355 0.12055229455834675 0.835550376863884 0.6339558343402543 0.11502270934413521 0.07273403807554481 3.204711687216252e-08 7.494211035812331 0.294528544599831 SIS(ph)VSEHVVR ddPTM_PC-9_AZD4547_30min_R2 2 SISVSEHVVR 10 0 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9 P49815 TSC2 Tuberin 1 S(0.007)IS(0.99)VS(0.003)EHVVR;S(0.031)IS(0.963)VS(0.006)EHVVR 90.697 0.0048425 24321000.0 31186.0 32819.0 86116.0 154856.0 104546.0 82350.0 67126.0 106668.0 79906.0 95651.0 True False 41102.499290903106 43427.099939475636 84974.04557280517 119156.3417013502 90031.59249531898 77200.64148186665 73100.08395970734 90184.9115867919 84129.66802866792 92302.28760389841 0.4453031485772963 0.47048779685544306 0.9206060627387557 1.290935953967815 0.9753993625995081 0.8363892541121165 0.7919639464777462 0.9770604166801053 0.9114581037221734 1.0 16.494078783367435 -5.27102749924645 5.1706070781463165 0.9656432646683706 0.45108377846077097 0.7223837760788352 0.1255165005597814 0.09119005440972591 8.095597500266226 0.03624007360499722 0.08662496815313163 5.357627322886799e-06 5.27102749924645 -0.5145594862075996 down SISADS(ph)FDQR ddPTM_PC-9_AZD4547_30min_R2 1 SISADSFDQR 10 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 SIS(0.044)ADS(0.956)FDQR 144.77 0.00013483 6600200.0 17295.0 19798.0 21897.0 19945.0 17807.0 20412.0 13774.0 24152.0 18885.0 13498.0 True False 22794.45024165234 26197.316329008794 21606.63147275436 15346.988397178218 15334.805421193954 19135.634413210275 14999.85931622632 20419.863357747367 19883.222545508364 13025.439128471438 1.749994761545311 2.011242467192206 1.658802537069623 1.1782319387322813 1.1772966170234236 1.4690970664768581 1.151581852118838 1.567690974280702 1.5264915331757956 1.0 13.669044390655062 -5.571538005122271 4.543617535211798 1.3175340176940586 1.8744720363788256 0.6333636708088775 0.18249970797456297 0.12390868681778633 5.50574306425198 0.050021541742578786 0.09217063884970808 2.682019893702743e-06 5.571538005122271 0.556938018684767 SISADS(ph)FDQR ddPTM_PC-9_Lapatinib_30min_R1 1 SISADSFDQR 10 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 SIS(0.322)ADS(0.678)FDQR 108.43 0.0020288 3855600.0 5481.6 10184.0 10452.0 10237.0 14926.0 20059.0 21858.0 25137.0 17826.0 18508.0 True False 5403.431378797673 10160.41957370309 9592.676905886754 10989.863129630905 14048.082025645059 19201.12332981283 22989.700287984604 26304.956787130133 15818.248163898177 21707.083139640185 0.24892480228862474 0.46806931674522106 0.4419145973771657 0.5062800496471067 0.6471658092095887 0.8845556635266616 1.0590874941646204 1.2118144394579475 0.728713667430141 1.0 14.40587825830329 -6.576611663554889 1.4005198512086163 1.0213775939367251 0.3956711107333718 0.8201264485739308 0.12553435658719636 0.1622705403314041 0.6591921333689048 0.05309682272269414 0.056364185008989355 2.6508694275192615e-07 6.576611663554889 -0.6257064832033533 down SISAS(ph)KASPPGDLQNPK ddPTM_PC-9_AZD4547_30min_R2 2 SISASKASPPGDLQNPK 17 1 O00273 O00273 DFFA DNA fragmentation factor subunit alpha 1 S(0.009)IS(0.137)AS(0.853)KAS(0.001)PPGDLQNPK;S(0.005)IS(0.028)AS(0.844)KAS(0.123)PPGDLQNPK 81.656 0.0023398000000000004 272780000.0 119085.0 108430.0 143940.0 183545.0 167705.0 157186.0 139334.0 145181.0 131395.0 171318.0 True False 156951.5528781246 143477.87703578244 142031.26155127486 141231.5359919818 144422.05554901628 147357.13457156936 151734.45607427592 122746.61237748942 138340.2714517911 165320.20896514083 0.9493791101559712 0.8678786334345607 0.8591282483874876 0.854290814632116 0.8735898439341369 0.8913437473493689 0.9178215840887936 0.7424779653125867 0.8368019392049119 1.0 17.33490356683305 SISASKAS(ph)PPGDLQNPK ddPTM_PC-9_AZD4547_30min_R2 1 SISASKASPPGDLQNPK 17 1 O00273 O00273 DFFA DNA fragmentation factor subunit alpha 1 SISAS(0.003)KAS(0.997)PPGDLQNPK 142.35 0.00052043 13093000.0 29831.0 31273.0 31790.0 42528.0 44097.0 43134.0 30238.0 39094.0 31165.0 43553.0 True False 39316.63747665397 41381.38567315345 31368.44382878299 32723.826651050156 37974.89271962654 40436.82416124883 32929.123421232136 33052.92059074926 32812.318275391495 42028.22272650148 0.935481800705846 0.9846094597538105 0.7463661747705354 0.7786155237636468 0.9035569494991028 0.9621350021006438 0.7835002597068712 0.7864458320267557 0.7807210523489786 1.0 15.35907082919004 -7.297821128648713 24.998261881469126 0.8198706123907505 0.8793383720275015 0.04382519490286074 0.09269407681295544 1689.802137064521 1161073.5263204721 0.04020247674923316 0.02710544706297463 5.0370802653621713e-08 7.297821128648713 0.059467759636750994 SISASKAS(ph)PPGDLQNPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SISASKASPPGDLQNPK 17 1 O00273 O00273 DFFA DNA fragmentation factor subunit alpha 1 SISASKAS(1)PPGDLQNPK;SIS(0.003)AS(0.024)KAS(0.972)PPGDLQNPK 127.37 1.6272999999999998e-05 186503000.0 206651.0 162000.0 194005.0 260344.0 247912.0 238523.0 258159.0 247019.0 203227.0 182864.0 True False 241632.93275670314 178082.28937929854 198630.8149680596 245757.76972663577 199335.42325118306 226014.4339842565 233704.31061069568 240535.0129882651 206198.81040728922 216015.7956493721 1.118589184787726 0.8243947570776461 0.919519863679177 1.1376842558566393 0.9227817005323817 1.0462866074438082 1.081885284861459 1.1135065945764984 0.9545543176017673 1.0 17.720777284380304 -5.724357529480387 24.99990504541318 1.0389399835216309 0.9411905219299223 0.13937912045061251 0.09215209564727297 280.9209247514408 189389.73040492728 0.0241249103001408 0.04178428702915972 1.8864377148204773e-06 5.724357529480387 -0.09774946159170861 SISASKAS(ph)PPGDLQNPK ddPTM_PC-9_Lapatinib_30min_R1 2 SISASKASPPGDLQNPK 17 1 O00273 O00273 DFFA DNA fragmentation factor subunit alpha 1 S(0.001)IS(0.007)AS(0.023)KAS(0.969)PPGDLQNPK;SIS(0.001)AS(0.078)KAS(0.921)PPGDLQNPK 148.52 0.00034379 102756600.0 78534.0 81884.0 83806.0 81536.0 91305.0 80316.0 73299.0 64310.0 83109.0 65027.0 True False 77414.0907586281 81694.40262893798 76915.79418051516 87532.4294361227 85934.61941253665 76881.07190574035 77094.06356523842 67298.07737519735 73748.38924343161 76266.83030696897 1.0150427184011905 1.0711655683096228 1.0085091234411363 1.1477129583570003 1.1267626970552658 1.0080538498361489 1.0108465666521067 0.8824029673755552 0.9669785534104302 1.0 16.218768121323208 -7.258031310119215 2.1909874191248773 0.9468919312630483 1.0722540513960226 0.48860349083666155 0.05192070043819942 0.25958413487401444 2.438941527299608 0.02594866666153888 0.016879791036818186 5.520376391265335e-08 7.258031310119215 0.12536212013297432 SISASKAS(ph)PPGDLQNPKR ddPTM_PC-9_Lapatinib_30min_R1 1 SISASKASPPGDLQNPKR 18 2 O00273 O00273 DFFA DNA fragmentation factor subunit alpha 1 S(0.03)IS(0.288)AS(0.288)KAS(0.393)PPGDLQNPKR 42.123000000000005 0.04133 20987000.0 155110.0 34791.0 43506.0 37565.0 31321.0 38049.0 14309.0 11901.0 42472.0 24940.0 True False 152898.1029563096 34710.44357705267 39929.10461801658 40327.65541316647 29478.76035945525 36421.732966551106 15049.850005525293 12453.963906736511 37688.35611001254 29250.845769538904 5.2271344275294025 1.1866475195462298 1.365058122852562 1.3786833970853134 1.007791726492698 1.2451514480473513 0.5145099093578288 0.4257642327629978 1.2884535512904807 1.0 14.836190719455026 -4.760455943944179 5.699670943012297 1.0250110281228038 5.413529990410549 0.9414781768369543 0.31296427758096457 0.034207310503701675 3.7993103193875726 0.08649113657875952 0.59038756706603 1.735977356373543e-05 4.760455943944179 4.388518962287745 up SISES(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 1 SISESSR 7 0 Q9H307 Q9H307 PNN Pinin 1 S(0.011)IS(0.149)ES(0.84)SR 105.14 0.010247 41180000.0 26836.0 23521.0 33238.0 22716.0 27218.0 30897.0 25447.0 26180.0 28754.0 22702.0 True False 26453.313718880338 23466.538569625944 30505.29994239036 24386.61041835458 25617.090752646873 29575.607334424818 26764.52114687273 27396.41837478882 25515.421726956596 26626.010451486465 0.9935139838947789 0.8813388927486079 1.1456954844200973 0.9158942704836629 0.9621077404488412 1.110778777328005 1.0052020822135046 1.028934410759962 0.9582893304066938 1.0 14.700548655899649 SISGT(ph)STSEKPNSMDTANTSPFK ddPTM_PC-9_AZD4547_30min_R2 1 SISGTSTSEKPNSMDTANTSPFK 23 1 Q9UJF2-2;Q9UJF2 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 S(0.14)IS(0.052)GT(0.202)S(0.202)T(0.202)S(0.202)EKPNSMDTANTSPFK 69.08800000000001 0.00087324 35523000.0 24697.0 25595.0 25554.0 35971.0 29740.0 31522.0 29320.0 45042.0 34661.0 29977.0 True False 32550.13227048786 33868.083212495185 25215.137263313005 27678.441696410042 25611.1143497674 29550.924356908396 31929.423199633784 38081.79386219181 36493.10969816607 28927.514354288673 1.1252308743790187 1.1707913371918885 0.871666225949853 0.9568206019162013 0.8853548229583853 1.0215507628821658 1.1037734804511492 1.3164557934631518 1.26153630938414 1.0 14.820154742125482 -7.471496370317671 3.5015093379573323 1.2170908135129972 1.0000063856765324 0.3327411953258832 0.11702665464442731 0.2542536481317548 6.26855711583681 0.05804425571537177 0.035185872555947746 3.376786708312007e-08 7.471496370317671 -0.21708442783646476 SISGT(ph)STSEKPNSMDTANTSPFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SISGTSTSEKPNSMDTANTSPFK 23 1 Q9UJF2-2;Q9UJF2 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 S(0.052)IS(0.057)GT(0.232)S(0.232)T(0.203)S(0.203)EKPNS(0.017)MDT(0.002)ANT(0.001)SPFK;S(0.013)IS(0.045)GT(0.444)S(0.165)T(0.165)S(0.165)EKPNS(0.001)MDT(0.001)ANTSPFK 62.403999999999996 0.0022241 75040000.0 130303.0 111063.0 106046.0 125794.0 132362.0 121371.0 125348.0 134553.0 107152.0 98590.0 True False 152360.72429843887 122088.60065020366 108574.53882169479 118746.1700096508 106426.61626856719 115006.09109856575 113474.12999906843 131021.126320688 108718.89528833225 116463.5865619895 1.3082262773810642 1.048298478986135 0.9322616796100844 1.01959911690034 0.9138188116155946 0.9874853977414823 0.9743314056249686 1.1249964919374178 0.9335011783315206 1.0 16.829519427615693 -4.777792087510137 3.434600649154179 0.9883602257874591 1.3499734056279746 0.7446312709000121 0.05643456876702851 0.14763848784774944 2.8091417245499706 0.014060292701961387 0.1418092804417929 1.6680455752330477e-05 4.777792087510137 0.36161317984051555 SISGT(ph)STSEKPNSMDTANTSPFK ddPTM_PC-9_Lapatinib_30min_R1 2 SISGTSTSEKPNSMDTANTSPFK 23 1 Q9UJF2-2;Q9UJF2 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 S(0.032)IS(0.035)GT(0.229)S(0.229)T(0.229)S(0.229)EKPNS(0.014)MDT(0.002)ANTSPFK;S(0.038)IS(0.056)GT(0.275)S(0.275)T(0.275)S(0.081)EKPNS(0.001)MDT(0.001)ANTSPFK 51.688 0.016248 49960000.0 84684.0 89584.0 108674.0 98319.0 102757.0 109996.0 98316.0 87824.0 116262.0 98195.0 True False 83476.39063085639 89376.57375202462 99739.24321377148 105549.70724256901 96713.03528803495 105291.72749319971 103406.32141611748 91904.6236572746 103167.34926686475 115167.87491338697 0.7248235733587648 0.776054727233971 0.8660335470180488 0.9164856720847598 0.8397570534384597 0.9142456398747072 0.8978747024192739 0.7980057262182904 0.8957997127623712 1.0 16.81337881997962 -5.161191190935342 2.4107425461953667 0.8855740977408885 0.7273868850137246 0.5681024121701993 0.05003869139008326 0.2375035663811037 2.514629214282621 0.013053270396361803 0.054392893625399744 6.899360041025172e-06 5.161191190935342 -0.15818721272716385 SISLYYTGEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SISLYYTGEK 10 0 P19338;H7BY16 P19338 NCL Nucleolin 0 ;; 137.98 0.0003385 3484400.0 53138.0 53530.0 54717.0 69504.0 73094.0 63957.0 70692.0 62724.0 51964.0 51552.0 False True 62133.21387666011 58844.1046325545 56021.66079537807 65609.91621500839 58771.75540966935 60602.98233013621 63995.541994241015 61077.56146157152 52723.87519377041 60897.96951459253 1.0202838349441452 0.9662736722027181 0.9199265795217362 1.077374446766846 0.9650856322161334 0.9951560423638487 1.0508649550114513 1.002949062972222 0.8657739431055509 1.0 15.894106505545366 -8.195820393444743 24.99974526812302 0.9328858609054569 0.9989475159717913 0.2105131895486101 0.051767431563173996 257.4710290987827 98092.08564106673 0.03389140235199009 0.012809741708960232 6.370589281301618e-09 8.195820393444743 0.06606165506633443 SISLYYTGEK ddPTM_PC-9_Lapatinib_30min_R1 2 SISLYYTGEK 10 0 P19338;H7BY16 P19338 NCL Nucleolin 0 ; 177.06 0.0017968 18554300.0 105582.0 96681.0 114277.0 103795.0 98292.0 107510.0 103949.0 85159.0 98394.0 98161.0 False True 104076.38131863237 96457.1410845629 104881.58618197692 111428.4305499698 92510.65780950726 102912.04791805056 109330.97059363684 89115.79802821398 87311.8315852462 115127.99805868916 0.9040058289346525 0.8378252268001015 0.9109998258504513 0.9678656141763758 0.8035461344715454 0.8938924471316592 0.9496471096275195 0.774058435227764 0.7583892107698856 1.0 16.81287920059564 -7.764528448393262 24.999998253596154 0.8246678810625389 0.8929798369812337 0.06955470689023802 0.07615914195140679 160.4884767230536 1298793.0108342925 0.03807894453066537 0.019522325092970312 1.7197746839722323e-08 7.764528448393262 0.06831195591869488 SISNEGLT(ph)LNNSHVSK ddPTM_PC-9_Lapatinib_30min_R1 1 SISNEGLTLNNSHVSK 16 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 SIS(0.423)NEGLT(0.577)LNNSHVSK 195.45 2.0327999999999998e-11 7886400.0 11301.0 8722.2 38018.0 12284.0 19309.0 25626.0 14842.0 17127.0 39145.0 12110.0 True False 11139.84566765041 8702.004281790369 34892.30679372394 13187.406338222734 18173.282582954613 24530.035717123676 15610.44613753626 17922.78294518748 34736.07788487567 14203.197364439298 0.7843195712777579 0.6126792480950572 2.456651548128465 0.9284815242545449 1.279520527431046 1.7270784238019388 1.0990797168404 1.2618836790975634 2.445651989026412 1.0 13.793928119319684 SISQDSLDELS(ph)MEDYWIELENIK ddPTM_PC-9_AZD4547_30min_R2 1 SISQDSLDELSMEDYWIELENIK 23 0 Q8N392-2;Q8N392 Q8N392-2 ARHGAP18 Rho GTPase-activating protein 18 1 S(0.016)IS(0.018)QDS(0.063)LDELS(0.867)MEDY(0.035)WIELENIK 60.352 0.022802 0.0 13052.0 19325.0 17885.0 16138.0 22386.0 19773.0 20885.0 22004.0 23926.0 18046.0 True False 17202.264501534915 25571.42832902791 17647.833214148606 12417.633429614556 19278.090310487325 18536.59118422528 22743.724540393974 18603.787401617807 25190.679514102918 17414.21503277491 0.9878288782560058 1.4684226811774452 1.013415372495057 0.7130745431960959 1.1070318285495186 1.0644517223049084 1.3060436257154577 1.0683104214920986 1.446558427508337 1.0 14.08797782268102 -7.226335725740669 19.40369418256191 1.2109203852843553 1.062027590121463 0.10707166816778813 0.2064518836438594 103.4832115809295 57199.61115112523 0.08105764072944965 0.06277239920896839 5.9383292626185276e-08 7.226335725740669 -0.14889279516289222 SISREPS(ph)PALGPNLDGSGLLPR ddPTM_PC-9_AZD4547_30min_R2 2 SISREPSPALGPNLDGSGLLPR 22 1 Q9BRZ2 Q9BRZ2 TRIM56 E3 ubiquitin-protein ligase TRIM56 1 S(0.108)IS(0.033)REPS(0.859)PALGPNLDGSGLLPR;S(0.007)IS(0.025)REPS(0.965)PALGPNLDGS(0.002)GLLPR 69.07 0.0010031 10802800.0 10741.3 6437.700000000001 11819.8 27478.8 22232.1 12988.400000000001 10758.2 9717.7 12769.8 18768.6 True False 14156.80996708066 8518.560628915035 11663.061729079873 21143.98720322792 19145.55666897995 12176.233294755051 11715.658958605058 8216.052755530867 13444.785557936615 18111.517026717225 0.7816468353367212 0.47033943188463284 0.6439583007803871 1.1674332510102463 1.057092933780056 0.672292292069917 0.6468623772002472 0.4536369175155757 0.7423334852681597 1.0 14.144619771517268 -6.812224211548127 0.014038839167560636 1.5015533063983268 6.37546854154138e-06 0.02623281044779202 0.22593976686800943 11022.259246677371 62.97337037492122 3241.879228962965 3487.293593015379 1.5409047305838452e-07 6.812224211548127 -1.5015469309297853 SISREPS(ph)PALGPNLDGSGLLPR ddPTM_PC-9_Lapatinib_30min_R1 1 SISREPSPALGPNLDGSGLLPR 22 1 Q9BRZ2 Q9BRZ2 TRIM56 E3 ubiquitin-protein ligase TRIM56 1 S(0.017)IS(0.017)REPS(0.967)PALGPNLDGSGLLPR 62.717 0.0022811999999999997 3037700.0 10030.0 7790.8 11340.0 9477.2 10166.0 11456.0 6675.6 7579.1 11684.0 6170.6 True False 9886.970360723271 7772.760881265327 10407.668973665883 10174.18490301242 9568.055867124993 10966.053585240332 7021.22990403834 7931.252654864859 10368.02488202549 7237.179988192337 1.3661357568630519 1.074004086390943 1.4380834787370615 1.4058217316153376 1.3220696297087464 1.51523847729803 0.9701610178955994 1.0959037453545333 1.4326056418302728 1.0 12.821211936447208 -10.573236870399167 4.030795048121483 0.9999593821528524 1.2847456724448776 0.20181559492737933 0.17326731286072067 125989160.9686077 239707503.56824765 71608.0170956371 0.04439000917150908 2.6715489103837287e-11 10.573236870399167 0.2847862902920252 SISS(ph)PSVSSETMDKPVDLSTR ddPTM_PC-9_AZD4547_30min_R2 2 SISSPSVSSETMDKPVDLSTR 21 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 S(0.002)IS(0.155)S(0.672)PS(0.123)VS(0.037)S(0.011)ET(0.001)MDKPVDLSTR;S(0.005)IS(0.187)S(0.719)PS(0.024)VS(0.028)S(0.028)ET(0.009)MDKPVDLSTR 87.24 0.00067852 43554000.0 118134.0 127255.0 153739.0 191190.0 162637.0 150897.0 132326.0 182972.0 138456.0 142447.0 True False 155698.1546601535 168387.6901428435 151700.320408722 147114.09935605442 140057.65986896813 141461.38673575263 144102.7576505707 154697.88167827736 145774.50149647365 137459.97388749244 1.1326799377074563 1.2249943411211806 1.1035963133012445 1.0702322661319843 1.018897762803315 1.0291096581433608 1.0483252220643897 1.1254031068338026 1.0604868993776069 1.0 17.068652064852458 -5.527292085996569 3.1379420415278956 1.0534151739259217 1.1786363909209703 0.6365302678173286 0.038415002096614935 0.1559343594089581 3.1439798694439016 0.010897616644504806 0.022995963499659395 2.9696681011770116e-06 5.527292085996569 0.12522121699504862 SISS(ph)SNPDLAVAPGSVDDEVSR ddPTM_PC-9_AZD4547_30min_R2 2 SISSSNPDLAVAPGSVDDEVSR 22 0 Q96HP0;K7ESB7;K7EKT0;K7EP20 Q96HP0 DOCK6 Dedicator of cytokinesis protein 6 1 S(0.006)IS(0.206)S(0.728)S(0.06)NPDLAVAPGSVDDEVSR;S(0.001)IS(0.08)S(0.655)S(0.264)NPDLAVAPGSVDDEVSR 241.08 4.593199999999999e-52 15448300.0 23003.0 21648.0 33749.0 48088.0 35906.0 34507.0 32553.0 35247.0 27213.0 32607.0 True False 30317.47550787677 28645.292650286985 33301.46620879515 37002.05455219384 30921.07168267478 32349.2718350307 35450.153936482886 29800.38604548367 28651.423623559396 31465.438854798376 0.9635166904164585 0.9103732124148864 1.0583506037360348 1.1759586358526555 0.9826995207460588 1.0280890085249055 1.1266378358831266 0.9470831213574257 0.9105680602700429 1.0 14.941480444157365 -10.002075577446998 8.209302716594962 0.9999999999998896 1.0158535884152913 0.0 0.08404840861722905 0.0 0.0 0.08621348339566183 0.020909840926135903 9.952322084857126e-11 10.002075577446998 0.01585358841540163 SISS(ph)SNPDLAVAPGSVDDEVSR ddPTM_PC-9_Lapatinib_30min_R1 1 SISSSNPDLAVAPGSVDDEVSR 22 0 Q96HP0;K7ESB7;K7EKT0;K7EP20 Q96HP0 DOCK6 Dedicator of cytokinesis protein 6 1 S(0.017)IS(0.123)S(0.693)S(0.167)NPDLAVAPGSVDDEVSR 127.67 7.2292999999999995e-06 7246600.0 23169.0 17810.0 22173.0 19579.0 15648.0 18817.0 9629.3 12688.0 16992.0 16211.0 True False 22838.60581132576 17768.76203924314 20350.02153025517 21018.904973629342 14727.615405151673 18012.240774569414 10127.858037473237 13277.53079982127 15078.182026307508 19013.049750200276 1.2012068611499418 0.934556121858145 1.0703186389148753 1.1054988678714175 0.7746056313241666 0.9473619966928073 0.5326793002982888 0.6983377719127575 0.7930438422246636 1.0 14.214702342708755 -6.408078014446102 1.8775613316080033 0.7519983338806981 1.0714420960409996 0.47944779624039613 0.14024175199657288 0.2845888100316738 1.9902643777288758 0.04989739633449268 0.05886839005016604 3.9077069343250913e-07 6.408078014446102 0.31944376216030146 SISSPSVS(ph)SETMDKPVDLSTR ddPTM_PC-9_Lapatinib_30min_R1 1 SISSPSVSSETMDKPVDLSTR 21 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 SIS(0.002)S(0.01)PS(0.21)VS(0.694)S(0.066)ET(0.018)MDKPVDLSTR 67.655 0.0054984 11881000.0 36184.0 42131.0 44038.0 43275.0 46319.0 53259.0 52957.0 61874.0 56607.0 46366.0 True False 35668.00952466706 42033.44825802092 40417.36563159595 46457.58786116809 43594.60748665776 50981.23672279283 55698.854339408965 64748.891922142255 50231.32356186381 54380.3013211885 0.6558994462719083 0.7729535739376862 0.7432354115303129 0.8543091290865386 0.8016617493377469 0.9374945611588351 1.02424688694593 1.190668134398766 0.9237043992305335 1.0 15.73079652490587 -6.764654569410039 1.178794226025399 1.0564838173568851 0.7410902677874853 0.7406713740225448 0.07605198738850029 0.22623912696977355 0.6645759237866987 0.03844206528859211 0.03455864944634738 1.7192753263945063e-07 6.764654569410039 -0.3153935495693998 SISSPSVSSET(ph)MDKPVDLSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SISSPSVSSETMDKPVDLSTR 21 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 S(0.001)IS(0.023)S(0.133)PS(0.133)VS(0.108)S(0.108)ET(0.494)MDKPVDLSTR 66.711 0.0025278 14622000.0 47717.0 54005.0 53077.0 57740.0 71066.0 52556.0 70000.0 48169.0 49190.0 42742.0 True False 55794.54564629063 59366.259493388876 54342.55697564346 54505.01499560571 57141.12745154953 49799.870840449665 63369.093243887175 46904.614789274216 49909.31069166277 50490.78625451419 1.1050441037903673 1.175784017189496 1.0762866060693381 1.0795041836119679 1.1317139559584648 0.9863160100026616 1.2550625162471416 0.928973744889557 0.9884835312343857 1.0 15.623732523103183 -7.794152979282893 24.999967337654585 0.9690463787639472 1.1107208596834528 0.481616632294506 0.06791116450831149 164.4017092848783 125634.779780351 0.03491841667625503 0.016776019384548133 1.6063753111472823e-08 7.794152979282893 0.14167448091950563 SISSPSVSSET(ph)MDKPVDLSTR ddPTM_PC-9_Lapatinib_30min_R1 1 SISSPSVSSETMDKPVDLSTR 21 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 SIS(0.005)S(0.019)PS(0.004)VS(0.005)S(0.005)ET(0.962)MDKPVDLSTR 91.37799999999999 0.00026798 7970300.0 41681.0 48456.0 63426.0 42461.0 54361.0 60557.0 54851.0 51825.0 66118.0 49792.0 True False 41086.62129664076 48343.803109127744 58211.35911144024 45583.723585743704 51163.59285783807 57967.118275261775 57690.916391995794 54232.97869646415 58671.09458659369 58398.48085633047 0.7035563373252871 0.8278263817865601 0.9967957771821054 0.7805635166758345 0.876111708859493 0.9926134622897141 0.9878838549571967 0.9286710527605314 1.0046681647581535 1.0 15.833643219724186 -3.0397301985183596 0.3340970393313979 0.9910506482748075 2.4747810321908057e-15 0.5958714469406245 0.0651746756883358 17.08055822458261 0.6060612407969815 0.06350878893227106 8.643726050371908 0.0009125775937902017 3.0397301985183596 -0.991050648274805 SISSS(ph)NPDLAVAPGSVDDEVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SISSSNPDLAVAPGSVDDEVSR 22 0 Q96HP0;K7ESB7;K7EKT0;K7EP20 Q96HP0 DOCK6 Dedicator of cytokinesis protein 6 1 SIS(0.008)S(0.04)S(0.952)NPDLAVAPGSVDDEVSR 187.57 2.238e-52 0.0 1194.3 2506.3 2690.2 2362.0 3119.7 2939.5 2291.7 3852.9 2425.7 1143.0 True False 1396.471401499778 2755.1089004403398 2754.344570640314 2229.6647977073203 2508.417179953832 2785.347445305994 2074.613585528804 3751.7654574849935 2461.171273526456 1350.2168520169778 1.034257126485797 2.040493640947163 2.0399275616548747 1.651338297530954 1.8577883813305354 2.062888965683692 1.5365039937323473 2.7786391881278476 1.822797034305945 1.0 10.398975415053275 -4.756475215150388 24.970059928182632 1.9155693220641006 1.0342557528095715 0.24362359265804723 0.43143771121327834 199.14689024038353 1001604.9653717445 0.10071340662663777 0.812690301585085 1.751962414493298e-05 4.756475215150388 -0.8813135692545291 SISSS(ph)NPDLAVAPGSVDDEVSR ddPTM_PC-9_Lapatinib_30min_R1 1 SISSSNPDLAVAPGSVDDEVSR 22 0 Q96HP0;K7ESB7;K7EKT0;K7EP20 Q96HP0 DOCK6 Dedicator of cytokinesis protein 6 1 S(0.004)IS(0.061)S(0.206)S(0.723)NPDLAVAPGS(0.006)VDDEVSR 71.89399999999999 0.001474 8065300.0 25338.0 18717.0 22840.0 20780.0 21928.0 22027.0 19153.0 15288.0 14474.0 14917.0 True False 24976.675473579882 18673.661936469052 20962.183364949626 22308.230520047888 20638.23815210671 21084.956557444893 20144.64862365125 15998.33629158791 12843.785702023013 17495.3835743469 1.4276151973142583 1.0673479582265253 1.1981551176554952 1.275092393673378 1.1796390781833508 1.205172579831934 1.1514265199185978 0.9144318684756316 0.7341242704078564 1.0 14.0946866745783 -7.749703001570001 3.0996704073460126 0.8530595703000682 1.2151201006478303 0.6855656260607645 0.10410799572097396 0.1344247318931824 2.6368878187113096 0.05818878531905459 0.027425798229351327 1.779495927508508e-08 7.749703001570001 0.3620605303477621 SIT(ph)SPTTLYDR ddPTM_PC-9_AZD4547_30min_R2 1 SITSPTTLYDR 11 0 Q08999;F5H837 Q08999 RBL2 Retinoblastoma-like protein 2 1 S(0.408)IT(0.421)S(0.171)PTTLYDR 155.47 0.0015831 19212000.0 71347.0 92298.0 118720.0 154040.0 133580.0 112830.0 114860.0 140460.0 102560.0 123350.0 True False 94033.86189020934 122131.52351423653 117145.6952297299 118528.45789427598 115034.72275863917 105774.72226349742 125082.3174866966 118755.13444970145 107981.11221961021 119031.55404481768 0.7899910460280455 1.0260432579772223 0.984156647955905 0.9957734219755522 0.9664220859901264 0.8886275837722087 1.0508332726597915 0.9976777620242432 0.9071637607869358 1.0 16.86098454233661 -4.752648701596543 24.999325103789438 0.9791745054702192 0.7899906861506047 0.5958268828218904 0.04685616776464576 239.49627248910588 681039.7971634294 0.011598893099351209 0.13518165269231258 1.767466936831964e-05 4.752648701596543 -0.18918381931961448 SIT(ph)SPTTLYDR ddPTM_PC-9_Lapatinib_30min_R1 2 SITSPTTLYDR 11 0 Q08999;F5H837 Q08999 RBL2 Retinoblastoma-like protein 2 1 S(0.006)IT(0.471)S(0.471)PT(0.012)T(0.039)LYDR;S(0.05)IT(0.571)S(0.376)PT(0.002)T(0.002)LYDR 174.23 0.0024881 42643000.0 143285.0 158274.0 163838.0 138740.0 141226.0 143520.0 137183.0 142631.0 162250.0 110985.0 True False 141241.7296247493 157907.52627732564 150367.87207296884 148943.40242307266 132919.36434099908 137381.98416146048 144285.6644984257 149258.15696006487 143975.69643175564 130168.6093717836 1.0850675159426417 1.2130998943555968 1.1551776791552923 1.144234413672386 1.0211322451894593 1.0554156245848356 1.1084520699327853 1.1466524662160158 1.1060707886994219 1.0 16.990022053786802 -14.522878745221309 0.07623764431415561 0.6574562549474997 1.228934931838555 0.3216883241757911 0.05102568023540857 367.37662175177223 1.988629778365977 22.10352440743143 2.2864231827847354 3.0000000004077545e-15 14.522878745221309 0.5714786768910552 SITNNS(ph)SDPFLNGGPYHSR ddPTM_PC-9_Lapatinib_30min_R1 1 SITNNSSDPFLNGGPYHSR 19 0 Q9GZV5;C9J337 Q9GZV5 WWTR1 WW domain-containing transcription regulator protein 1 1 SIT(0.001)NNS(0.5)S(0.5)DPFLNGGPYHSR 102.84 0.00018195 3406500.0 22043.0 27792.0 23418.0 20183.0 20120.0 27312.0 21795.0 20685.0 22096.0 16473.0 True False 21728.66277780887 27727.649331535373 21492.66243609415 21667.32514851429 18936.581157441964 26143.929427381623 22923.438456245964 21646.100614305076 19607.31579880477 19320.33610110724 1.1246524213708482 1.4351535701258484 1.1124372952736787 1.1214776510680136 0.9801372532208027 1.353181916223669 1.1864927367869254 1.120379091803923 1.014853763215904 1.0 14.237832571403414 -2.722623525909747 0.023246997555651742 2.3211828068694213e-07 2.5949953297882242 0.20497776535629508 0.12515621250349962 3056.2031904283103 6.762203225226674 284.35118962987315 496.6235885246136 0.0018939847337085857 2.722623525909747 2.5949950976699436 SITS(ph)PPSTSTTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SITSPPSTSTTK 12 0 K7EN08;Q14938-6;Q14938-5;Q14938-3;Q14938-4;Q14938;C9JWJ8;Q14938-2 K7EN08 NFIX Nuclear factor 1;Nuclear factor 1 X-type 1 SIT(0.022)S(0.839)PPS(0.045)T(0.045)S(0.022)T(0.022)T(0.005)K 86.911 0.031654 0.0 35014.0 32432.0 29913.0 31862.0 39066.0 23423.0 29004.0 23038.0 20536.0 16734.0 True False 40941.17864197709 35651.63462437898 30626.239365684236 30076.87543799775 31411.297737627472 22194.65664616511 26256.531149224338 22433.27691077871 20836.30014970495 19767.741733728883 2.0711105594889903 1.8035259214029524 1.549303900173278 1.5215129701274284 1.5890180153472802 1.1227714801785011 1.3282514261314888 1.134842675149976 1.0540556645452743 1.0 14.270860446588266 -1.5228787452810024 0.21651584507323793 0.9374001991920848 6.868687740140455 0.9103195882038164 0.09999483583882147 13.755005472658311 0.17428662624255625 0.16063529241501487 28.36153669430111 0.029999999999954074 1.5228787452810024 5.93128754094837 up SITS(ph)PPSTSTTK ddPTM_PC-9_Lapatinib_30min_R1 1 SITSPPSTSTTK 12 0 K7EN08;Q14938-6;Q14938-5;Q14938-3;Q14938-4;Q14938;C9JWJ8;Q14938-2 K7EN08 NFIX Nuclear factor 1;Nuclear factor 1 X-type 1 SIT(0.227)S(0.766)PPS(0.003)T(0.003)S(0.001)T(0.001)TK 101.89 0.0069191999999999995 0.0 31864.0 26501.0 30156.0 26753.0 22721.0 19803.0 19224.0 16330.0 19612.0 18464.0 True False 31409.61351685804 26439.63856271658 27676.690085526294 28720.504865391795 21384.595451204714 18956.071853047695 20219.324656245593 17088.75141559593 17403.090036484395 21655.477798266485 1.450423482199611 1.2209215058202532 1.2780456909494653 1.3262466491360843 0.9874912782075187 0.8753476616694702 0.9336817614739558 0.7891191122536155 0.8036345445066794 1.0 14.402444383383475 -6.378137665545243 2.8852404347104623 0.8718036949210525 1.3129297160077622 0.8737662997493973 0.07899565446220289 0.09004374277864652 1.4449142240934283 0.02620814309514235 0.030420789966348838 4.186608341941606e-07 6.378137665545243 0.44112602108670973 SITS(ph)PTTLYDR ddPTM_PC-9_AZD4547_30min_R2 2 SITSPTTLYDR 11 0 Q08999;F5H837 Q08999 RBL2 Retinoblastoma-like protein 2 1 SIT(0.017)S(0.979)PT(0.004)T(0.001)LYDR;SIT(0.075)S(0.308)PT(0.308)T(0.308)LYDR 133.05 7.7503e-05 31150000.0 66583.0 91114.0 124360.0 142880.0 114257.0 119612.0 101066.0 128274.0 104054.0 105769.0 True False 87755.00898756512 120564.81866861833 122710.90514461936 109941.22347399482 98394.38776938051 112132.64273137899 110060.67820921495 108452.20074327974 109554.08200954873 102066.0595035782 0.85978639142514 1.1812430033550145 1.2022694492317243 1.0771575194410297 0.9640265162380549 1.098628116699733 1.07832788631716 1.0625687057065003 1.0733644714255675 1.0 16.639143674380442 -6.003278683035253 24.9954613534412 1.0505207180875082 1.0992138648258143 0.01864699793273028 0.09405471250937653 478.86888377157277 3650789.857931217 0.026732715706807967 0.03878301107998286 9.924789788137395e-07 6.003278683035253 0.04869314673830605 SITS(ph)PTTLYDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SITSPTTLYDR 11 0 Q08999;F5H837 Q08999 RBL2 Retinoblastoma-like protein 2 1 SIT(0.05)S(0.942)PT(0.006)T(0.002)LYDR;S(0.001)IT(0.45)S(0.548)PT(0.001)T(0.001)LYDR 125.36 0.00046509 33210000.0 195611.0 234910.0 205470.0 249470.0 236460.0 209110.0 220360.0 167025.0 188938.0 178202.0 True False 228724.0788066429 258230.3123338952 210369.18404931395 235493.004692652 190127.36044231273 198143.9034828837 199485.9055317569 162640.77072761566 191700.8608144214 210508.61195374376 1.0865307442001553 1.2266971404981646 0.9993376617558029 1.1186858461847546 0.903180913491988 0.9412626953543496 0.947637741184627 0.7726086321036292 0.9106556688357478 1.0 17.683519729908113 -6.131023348792893 1.0648698226561293 0.8907503016199584 1.1452991629571534 0.5814936745131233 0.0785279004552448 0.3410181336418063 0.7990343483269268 0.03191686190373801 0.05629282485576514 7.395655130375172e-07 6.131023348792893 0.254548861337195 SITS(ph)PTTLYDR ddPTM_PC-9_Lapatinib_30min_R1 2 SITSPTTLYDR 11 0 Q08999;F5H837 Q08999 RBL2 Retinoblastoma-like protein 2 1 S(0.027)IT(0.019)S(0.954)PT(0.001)TLYDR;SIT(0.001)S(0.793)PT(0.159)T(0.047)LYDR 150.51 0.00033797 15378500.0 69789.0 67335.0 75449.0 62369.0 65879.0 74916.0 56935.0 65909.0 69651.0 52473.0 True False 68793.79606226485 67179.08994455 69245.87446156236 66955.82431688484 62004.12674309738 71712.01731772562 59882.81571490545 68971.37275263388 61806.17092245443 61542.888134122455 1.117818778870765 1.0915816917487586 1.1251645244638588 1.0879538862551559 1.0074945882937723 1.1652364634146068 0.973025763503345 1.120704192535168 1.0042780375818274 1.0 15.909304528762105 -4.985134727405391 0.09305242026836845 0.9293434840053366 1.2830929631480743 0.2797400467623766 0.05386588364433913 83.05992664077908 1.3373464995981652 1.2946872778620686 4.397496006694015 1.034821093319378e-05 4.985134727405391 0.3537494791427377 SITS(ph)TPLSGK ddPTM_PC-9_AZD4547_30min_R2 1 SITSTPLSGK 10 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 SITS(0.498)T(0.498)PLS(0.003)GK 169.82 0.001341 46088000.0 312210.0 272790.0 371560.0 481240.0 493240.0 456260.0 318330.0 426710.0 362900.0 378690.0 True False 411486.2856285792 360964.03280080296 366632.8716270089 370297.55308388313 424762.1399421403 427729.99007306 346660.75331307674 360771.77432032116 382082.1531249662 365432.1783642658 1.1260264147247763 0.9877729827092321 1.0032856801722212 1.0133140292718488 1.1623556027371347 1.1704770827452835 0.9486322602043065 0.9872468700900796 1.0455624210085395 1.0 18.47924415143057 -7.292071662501972 24.996357306611213 0.9942976337379621 1.0707465691741938 0.2788188656046644 0.06397185597459942 1133.7109702175833 925118.4061086819 0.029590778706649657 0.019952217767304836 5.10420769001015e-08 7.292071662501972 0.07644893543623166 SITS(ph)TPLSGK ddPTM_PC-9_Lapatinib_30min_R1 2 SITSTPLSGK 10 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 S(0.028)IT(0.189)S(0.65)T(0.133)PLSGK;SIT(0.023)S(0.952)T(0.025)PLSGK 179.94 0.0012411 51371000.0 271220.0 199787.0 269280.0 282440.0 657180.0 736850.0 631930.0 622930.0 883020.0 734610.0 True False 267352.3530643431 199324.40547637688 247140.83785085962 303211.5797922205 618525.9644655924 705336.6431812443 664648.2433427627 651873.6019177693 783564.9889871747 861586.3596937021 0.3103024439237735 0.23134582300866233 0.2868439536794888 0.3519224467527708 0.7178920110637328 0.8186488043195052 0.7714238228876421 0.7565969384073273 0.9094445149592847 1.0 19.716635884302654 -6.290010485760227 2.2331208641901377 0.8327926302186506 0.26911115321687923 0.9369636256555165 0.0686862714781854 0.07055140198228083 0.6910534389116303 0.022698512831505084 0.02854471196671883 5.128490014334327e-07 6.290010485760227 -0.5636814770017713 down SITST(ph)PLSGK ddPTM_PC-9_AZD4547_30min_R2 1 SITSTPLSGK 10 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 SIT(0.005)S(0.224)T(0.771)PLSGK 177.04 0.0039963 42963000.0 331870.0 248570.0 403120.0 452790.0 537320.0 397630.0 296980.0 403800.0 348160.0 432110.0 True False 437397.75667517516 328915.3914487177 397774.36540607107 348406.26103576465 462722.3928183271 372766.1332414651 323410.64467350795 341401.9884008938 366563.02681727253 416981.96042404714 1.0489608620727053 0.788800050520721 0.9539366283413243 0.8355427670814707 1.1096940317220547 0.8939622540562258 0.7755986478278762 0.8187452235432613 0.8790860555322312 1.0 18.66962544522972 -6.999091865844077 24.99390206787595 0.8506139803677777 0.9396369256089177 0.10782218465590165 0.10219233843646325 60.93898655527225 1677117.287716568 0.03511587392760619 0.03071379327858689 1.0020932439524788e-07 6.999091865844077 0.08902294524113996 SITST(ph)PLSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SITSTPLSGK 10 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 S(0.006)IT(0.002)S(0.069)T(0.923)PLSGK;S(0.012)IT(0.012)S(0.029)T(0.947)PLSGK;SITS(0.034)T(0.96)PLS(0.006)GK;SIT(0.018)S(0.039)T(0.931)PLS(0.011)GK 119.74 0.0018682000000000002 62768300.0 280939.0 303021.0 281554.0 433719.0 943890.0 1000700.0 956220.0 950410.0 836510.0 831790.0 True False 328496.4239018218 333102.9222839768 288267.31515949144 409419.1305659695 758941.5302710587 948221.5303683302 865639.9191667108 925462.7445426347 848742.376228558 982586.9425539845 0.33431792106658675 0.3390060541799595 0.2933758863212796 0.4166747112492547 0.7723912230080968 0.9650255761629295 0.8809804829246971 0.94186346720335 0.8637834877211663 1.0 19.906225541901705 -6.306511744167744 2.4221424414418333 0.9234594881890731 0.32347872470462585 0.9793109608713966 0.04041543111263267 0.03564578884628132 0.41131005822735517 0.012759579122856845 0.01572658776359589 4.937285666881263e-07 6.306511744167744 -0.5999807634844472 down SIVECQPDASATPGVGTADS(ph)PAAPTDSRDDQK ddPTM_PC-9_AZD4547_30min_R2 2 SIVECQPDASATPGVGTADSPAAPTDSRDDQK 32 1 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 SIVECQPDASAT(0.001)PGVGT(0.176)ADS(0.814)PAAPT(0.008)DSRDDQK;SIVECQPDASATPGVGT(0.031)ADS(0.968)PAAPTDSRDDQK 121.75 3.3201999999999995e-18 7551900.0 13882.599999999999 17191.9 17726.7 22703.0 20745.4 20300.1 17293.800000000003 19901.8 16683.0 17924.9 True False 18296.97802398164 22748.84546907193 17491.632375579982 17469.17410785345 17865.259301669954 19030.731537899755 18832.91469747021 16826.434107867528 17564.829320980476 17297.35470691494 1.05779053121152 1.3151632636623711 1.011231640441956 1.0099332761482784 1.0328318754154926 1.1002105154432584 1.0887742673127585 0.9727749932271926 1.015463324802989 1.0 14.078263802208046 -5.291487369636986 24.98297797865866 1.032078008759193 1.1864769484100306 0.4590287069348673 0.068355176272538 501.4507838294024 416923.3586417052 0.01719674924242731 0.03580503626388255 5.111079431106408e-06 5.291487369636986 0.15439893965083762 SIVLLSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SIVLLSTR 8 0 B4E1B9;Q9UHN6-2;Q9UHN6 B4E1B9 TMEM2 Transmembrane protein 2 0 64.567 0.039566000000000004 0.0 32740.0 35095.0 32470.0 34327.0 40480.0 30933.0 33209.0 29152.0 30344.0 25932.0 False True 38282.23535552437 38578.999665225136 33244.20794316073 32403.769479635575 32548.234588111405 29310.819025565695 30063.20310766071 28386.790889097196 30787.723594791958 30633.266322400963 1.2496948563245442 1.2593825046013378 1.085232230650196 1.0577967474509864 1.0625127025488006 0.9568297000092278 0.9813907139793516 0.9266654946403478 1.00504214179335 1.0 14.902811584419462 -5.3601747744326556 0.7727175391667641 0.9702689320215863 1.3412088706286827 0.8942188315391348 0.035267713310125286 0.38946570101623945 0.3037430613413968 0.015191877610880745 0.10878831168217148 4.363401992054582e-06 5.3601747744326556 0.3709399386070964 SIVNYKPK ddPTM_PC-9_Lapatinib_30min_R1 1 SIVNYKPK 8 1 P12814-4;P12814-3;P12814;P12814-2;H9KV75;H7C5W8;H0YJ11;H0YJW3 P12814-4 ACTN1 Alpha-actinin-1 0 80.219 0.025417 3951300.0 33126.0 29802.0 31164.0 30545.0 34434.0 30331.0 34358.0 28752.0 30353.0 31971.0 False True 32653.61716543558 29732.99530002944 28601.816216518837 32791.38119513297 32408.659819848708 29033.813835014364 36136.88912501488 30087.92288433645 26934.325508740127 37497.14475132031 0.8708294293337046 0.792940249110101 0.7627731766299817 0.8745034165295573 0.8642967360523516 0.7742939903175443 0.9637237545598046 0.8024057053911292 0.7183033718265107 1.0 15.194493124226273 -5.778998551108831 24.97992523485699 0.8498875427216332 0.807256853898671 0.06204187423217411 0.08234958775453864 781.3430809949965 1111547.0520219547 0.022789490543839986 0.03388925299262075 1.6634181998487377e-06 5.778998551108831 -0.04263068882296228 SIVPS(ph)SPQPQR ddPTM_PC-9_AZD4547_30min_R2 2 SIVPSSPQPQR 11 0 A0A1X7SBY3;H0Y860;Q9P246;Q9P246-2;H7C5K2;H7C5C6;H7C5A5;Q9P246-3 A0A1X7SBY3 STIM2 Stromal interaction molecule 2 1 SIVPS(0.5)S(0.5)PQPQR;SIVPS(0.5)S(0.5)PQPQR 112.02 0.0017392 32649000.0 41488.0 56914.0 106878.0 100594.0 89996.0 78013.0 76660.0 88718.0 79989.0 74217.0 True False 54680.32099599141 75310.33748606952 105460.72788715543 77403.60746180722 77501.60884403723 73134.8347774727 83482.5914899021 75008.67163682645 84217.05523921992 71618.6854198966 0.7634923857566437 1.0515459344796536 1.4725309082238065 1.0807739210513838 1.0821422983352647 1.0211697456981652 1.165653781557816 1.0473338235274012 1.175908978857399 1.0 16.128048417398034 -4.805098450384389 4.381790683472426 1.1336565040118722 0.745747706991007 0.4242676120354488 0.1274573632744051 0.1798737252186636 6.687183995849231 0.03224421280815853 0.19826255051959824 1.5663959429544355e-05 4.805098450384389 -0.3879087970208652 SIVPS(ph)SPQPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SIVPSSPQPQR 11 0 A0A1X7SBY3;H0Y860;Q9P246;Q9P246-2;H7C5K2;H7C5C6;H7C5A5;Q9P246-3 A0A1X7SBY3 STIM2 Stromal interaction molecule 2 1 SIVPS(0.5)S(0.5)PQPQR;SIVPS(0.857)S(0.143)PQPQR 161.25 0.00066113 21039700.0 81175.0 113780.0 114541.0 81340.0 155471.0 103760.0 113377.0 108651.0 88968.0 85384.0 True False 94916.32422066842 125075.32645417594 117272.09183916138 76782.78350783819 125007.57360791162 98318.64294095931 102637.10978160273 105799.02637525051 90268.98868908004 100863.44330062771 0.9410379133871759 1.240046168971088 1.1626818201082727 0.7612548312373582 1.2393744405029017 0.9747698444907982 1.01758482977513 1.0489333192791375 0.8949623940561849 1.0 16.622043856757692 -6.7127629511036195 0.4709835185098663 0.9713151514154443 1.0978683525196962 0.0541305177435798 0.14038580748936824 3.638745368366964 1.6936685479591513 0.1303910084616743 0.1932584335315114 1.9374792004660396e-07 6.7127629511036195 0.12655320110425183 SIVPSS(ph)PQPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SIVPSSPQPQR 11 0 A0A1X7SBY3;H0Y860;Q9P246;Q9P246-2;H7C5K2;H7C5C6;H7C5A5;Q9P246-3 A0A1X7SBY3 STIM2 Stromal interaction molecule 2 1 SIVPS(0.105)S(0.895)PQPQR;SIVPS(0.078)S(0.922)PQPQR 123.95 0.0012337 6495100.0 54506.0 57663.0 78359.0 62452.0 86498.0 59504.0 75609.0 60504.0 56799.0 51968.0 True False 63732.789257428514 63387.40155850908 80227.37573816223 58953.0169121158 69549.33783108831 56383.505489194744 68446.76815824387 58915.83410928704 57629.57792184904 61389.387021538365 1.0381727583477576 1.0325465790409296 1.30686067463118 0.9603128451410051 1.1329211970578408 0.9184568901040286 1.1149609318338596 0.9597071573400222 0.9387547378772458 1.0 15.905701644023974 -6.557445739481139 1.4871681426782941 0.9913794548181855 1.1033436918875617 0.18313549059504242 0.10102694454237436 0.6916127925733142 3.145002046437545 0.04106161885236444 0.044117492376860204 2.7704751592167666e-07 6.557445739481139 0.1119642370693762 SIVPSS(ph)PQPQR ddPTM_PC-9_Lapatinib_30min_R1 2 SIVPSSPQPQR 11 0 A0A1X7SBY3;H0Y860;Q9P246;Q9P246-2;H7C5K2;H7C5C6;H7C5A5;Q9P246-3 A0A1X7SBY3 STIM2 Stromal interaction molecule 2 1 SIVPS(0.074)S(0.926)PQPQR;SIVPS(0.152)S(0.847)PQPQR 182.23 7.726e-05 30857000.0 326780.0 331030.0 151593.0 105852.0 128836.0 142923.0 133377.0 118469.0 223110.0 56464.0 True False 322120.05727588705 330263.5203734231 139129.60870590215 113636.70919192061 121258.1197813218 136810.5164597855 140282.6084413269 123973.5022323473 197981.00234754413 66223.72716644923 4.864118512482063 4.9870874761145085 2.10090272261796 1.7159515789001394 1.831037378439106 2.0658836690952285 2.1183133967790018 1.8720405440295982 2.9895780684456366 1.0 16.015060589517716 -5.2690136394341565 7.128180094032064 1.9851640852383585 4.936142452626876 0.8683759423529495 0.46155057716695197 0.037755885235141035 13.44734061667893 0.11379024182253969 0.2611323169312928 5.382528779036863e-06 5.2690136394341565 2.950978367388517 SIYDDIS(ph)SPGLGSTPLTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SIYDDISSPGLGSTPLTSR 19 0 Q8NFH5-2;Q8NFH5;C9IYQ7;F8WCF5;F8WEL4 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 SIYDDIS(0.499)S(0.499)PGLGS(0.001)T(0.001)PLTSR 103.67 0.00027744 5015800.0 29674.0 27977.0 24605.0 29181.0 30512.0 33639.0 30408.0 27133.0 24172.0 18415.0 True False 34697.22211178467 30754.37166644829 25191.67651498213 27546.083176078453 24533.392632224673 31874.911621924955 27527.534105144605 26420.787499789865 24525.46977106877 21753.493726940203 1.595018370259052 1.4137670046242328 1.158051981497757 1.2662831783183648 1.1277909167225748 1.4652778087985965 1.2654304844400075 1.2145537554305377 1.1274267057477605 1.0 14.408959503625898 -1.5228787452803376 0.11213090001713721 0.9391375110001049 2.50792378400156 0.5109520420807891 0.11972269090202456 105.87980337481832 0.8293122946596916 1.125887594559207 25.738252936702157 0.029999999999999995 1.5228787452803376 1.568786273001455 SIYDDIS(ph)SPGLGSTPLTSR ddPTM_PC-9_Lapatinib_30min_R1 2 SIYDDISSPGLGSTPLTSR 19 0 Q8NFH5-2;Q8NFH5;C9IYQ7;F8WCF5;F8WEL4 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 SIYDDIS(0.499)S(0.499)PGLGS(0.001)T(0.001)PLTSR;SIYDDIS(0.499)S(0.499)PGLGS(0.001)TPLTSR 138.98 4.9714e-05 8570300.0 63422.0 61807.0 78824.0 53236.0 56766.0 64603.0 60282.0 59720.0 63109.0 58964.0 True False 62517.59064982962 61663.88968891074 72343.39498943897 57151.153030089976 53427.135486250016 61840.0802869484 63403.106997908704 62494.809218578615 56000.99985276842 69155.84883540876 0.9040101698212363 0.8916655746019557 1.0460922135684658 0.8264109831998445 0.7725613434867504 0.8942133070209012 0.9168148184950834 0.9036807482085362 0.809779661385562 1.0 16.07756365159051 -5.805056356472586 24.999994259730418 0.8690688849013266 0.9416983275766896 0.174331382755061 0.07122029875566398 228.49846566620315 130967.63582192229 0.020174041074910738 0.029923142866698837 1.5665477729475093e-06 5.805056356472586 0.07262944267536298 SIYDDISS(ph)PGLGSTPLTSR ddPTM_PC-9_AZD4547_30min_R2 2 SIYDDISSPGLGSTPLTSR 19 0 Q8NFH5-2;Q8NFH5;C9IYQ7;F8WCF5;F8WEL4 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 SIYDDIS(0.274)S(0.68)PGLGS(0.032)T(0.009)PLT(0.005)SR;SIYDDIS(0.094)S(0.905)PGLGSTPLTSR 209.23 1.0375999999999999e-20 13632200.0 113730.0 108532.0 137393.0 182736.0 135957.0 105431.0 84564.0 122349.0 90850.0 95511.0 True False 149893.77426904393 143612.84654106383 135571.07904900864 140609.0384430564 117081.71733864564 98838.38290315369 92090.03217782517 103442.77335032454 95652.14552604897 92167.18896128568 1.6263246818996073 1.5581775701262586 1.4709256143849037 1.5255867085424344 1.2703188483683188 1.072381440912451 0.9991628606195974 1.12233837785565 1.0378112493614962 1.0 16.49196562968799 -6.464129567495965 1.842669939410354 1.0438097238182225 1.5548787295033368 0.9605680670450694 0.04768697256100608 0.06434367389975752 0.4371218322436409 0.018306891698766373 0.02077979949470491 3.4345546604621533e-07 6.464129567495965 0.5110690056851144 SIYDDISS(ph)PGLGSTPLTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SIYDDISSPGLGSTPLTSR 19 0 Q8NFH5-2;Q8NFH5;C9IYQ7;F8WCF5;F8WEL4 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 SIYDDIS(0.212)S(0.788)PGLGSTPLTSR 191.4 1.6158e-11 5123400.0 21083.0 23714.0 23163.0 24825.0 25954.0 22954.0 24206.0 20371.0 18709.0 14327.0 True False 24651.935491769098 26068.16919963382 23715.293766166666 23434.13573373592 20868.500012347904 21750.251831792422 21913.032443736192 19836.282834858634 18982.58373104938 16924.371687530398 1.4565938367999944 1.540273971815475 1.4012510599515908 1.3846384472282542 1.2330442983430503 1.2851438288735797 1.2947619473449261 1.1720543132170564 1.1216123163399585 1.0 14.046814654702164 -5.758967087606168 0.1832936990182279 0.9230452193455081 1.8619426212663703 0.909618196221997 0.04670685586825476 3.151016555063465 0.15759661831571278 0.15914240304118196 0.7265607600222646 1.7419388787669172e-06 5.758967087606168 0.9388974019208622 SIYDDISSPGLGS(ph)TPLTSR ddPTM_PC-9_AZD4547_30min_R2 1 SIYDDISSPGLGSTPLTSR 19 0 Q8NFH5-2;Q8NFH5;C9IYQ7;F8WCF5;F8WEL4 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 SIYDDIS(0.274)S(0.195)PGLGS(0.309)T(0.222)PLT(0.001)SR 111.11 0.00013297 11387000.0 33937.0 37679.0 58220.0 88773.0 65560.0 80921.0 61070.0 76438.0 60558.0 74136.0 True False 44728.26006654842 49857.999896995774 57447.9647597278 68307.75637917782 56458.1256479741 75860.99707776724 66505.1116917338 64626.26347049912 63758.97224839272 71540.52120524223 0.6252157422536487 0.6969197184621904 0.8030129469551338 0.9548121152655578 0.7891768846078389 1.0603920100068887 0.9296145816569833 0.9033518680286543 0.8912287913792931 1.0 16.12647300861056 -5.26785129345084 1.1462098626289807 0.935792601682425 0.5823101812269499 0.7239795667051533 0.06771871088642151 0.4239284165304513 0.7939671759163186 0.02190486651469063 0.1475325222328994 5.396953876995027e-06 5.26785129345084 -0.35348242045547507 SIYDDISSPGLGS(ph)TPLTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SIYDDISSPGLGSTPLTSR 19 0 Q8NFH5-2;Q8NFH5;C9IYQ7;F8WCF5;F8WEL4 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 SIYDDIS(0.002)S(0.01)PGLGS(0.935)T(0.053)PLTSR 242.9 1.515e-53 2695500.0 9457.5 10294.0 13033.0 14106.0 16155.0 13651.0 12791.0 13950.0 12131.0 9597.6 True False 11058.46795586047 11315.920289324038 13343.756147927745 13315.686552269044 12989.543719637835 12935.117528787927 11579.343881179444 13583.827281246768 12308.39292540275 11337.568905440203 0.975382645794037 0.9980905416058131 1.1769503902661969 1.1744745865120754 1.1457080285884702 1.1409075117136585 1.0213251163239438 1.1981252237178222 1.0856289410948328 1.0 13.468823698482721 -5.18361055613825 6.463569885593538 1.1252144437518259 0.9834474233604459 0.40850489836710246 0.06270520643198223 0.21290405857046468 14.47205688055574 0.015374464570894716 0.04167057525455631 6.552234676944237e-06 5.18361055613825 -0.14176702039138 SIYDDISSPGLGST(ph)PLTSR ddPTM_PC-9_AZD4547_30min_R2 1 SIYDDISSPGLGSTPLTSR 19 0 Q8NFH5-2;Q8NFH5;C9IYQ7;F8WCF5;F8WEL4 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 SIYDDISSPGLGS(0.039)T(0.961)PLTSR 264.01 6.736799999999998e-78 10438000.0 13666.0 20719.0 28735.0 37920.0 37350.0 37163.0 28630.0 38976.0 31277.0 37971.0 True False 18011.503729541524 27416.011567872145 28353.955124884524 29178.129858159864 32164.597207929113 34839.19173516231 31178.01453634088 32953.154779378994 32930.23836673899 36641.6468474729 0.4915582480371988 0.7482199608002328 0.7738177064724382 0.7963105473839318 0.8778152723817173 0.9508085670981544 0.8508900996214686 0.8993360728722735 0.898710653039606 1.0 15.161196725923428 -4.2563704656813135 0.6110892683840332 0.9136164369756581 2.402640641086666e-20 0.8703047781838256 0.048484628357855324 2.175949727357769 0.3867803617425087 0.022605195403389282 1.6100176956556227 5.5415280300792136e-05 4.2563704656813135 -0.9136164369756581 down SIYDDISSPGLGST(ph)PLTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SIYDDISSPGLGSTPLTSR 19 0 Q8NFH5-2;Q8NFH5;C9IYQ7;F8WCF5;F8WEL4 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 SIYDDIS(0.001)S(0.005)PGLGS(0.385)T(0.608)PLTSR;SIYDDIS(0.005)S(0.013)PGLGS(0.282)T(0.7)PLTSR;SIYDDIS(0.001)S(0.002)PGLGS(0.057)T(0.939)PLTSR 185.71 4.653e-11 10651500.0 39671.7 42580.5 67711.0 61692.0 74869.0 66019.0 64744.0 59260.0 57012.0 50739.2 True False 46387.3352582088 46807.610635279016 69325.48703539744 58235.5972481626 60198.95690161349 62556.847420192746 58610.97961403188 57704.487791160136 57845.692643892646 59937.815308713805 0.7739243584252723 0.78093621521227 1.1566235218673184 0.9716002651784384 1.004356875397521 1.0436958220447214 0.9778631288469897 0.9627392572443496 0.9650951130927021 1.0 15.871178879137924 -5.232324755403051 23.885186689524836 1.0073634639482065 0.7774300624499781 0.7453086895359562 0.05441843545448423 195.41817366419 160316.74968257884 0.013696169585035695 0.03622000576461774 5.857000277398341e-06 5.232324755403051 -0.22993340149822838 SIYDDISSPGLGST(ph)PLTSR ddPTM_PC-9_Lapatinib_30min_R1 3 SIYDDISSPGLGSTPLTSR 19 0 Q8NFH5-2;Q8NFH5;C9IYQ7;F8WCF5;F8WEL4 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 SIYDDIS(0.001)S(0.001)PGLGS(0.217)T(0.77)PLT(0.008)S(0.002)R;SIYDDISS(0.003)PGLGS(0.266)T(0.731)PLTSR;SIYDDIS(0.006)S(0.103)PGLGS(0.209)T(0.679)PLT(0.003)SR 207.92 3.4392e-20 19569400.0 83270.0 79924.3 81285.5 72468.6 69970.1 69429.5 60072.3 57389.8 63056.0 45943.2 True False 82082.55453015238 79739.24019388431 74602.51996110387 77798.18259216266 65854.59628450948 66460.16213306943 63182.54975797869 60056.33961976532 55953.96927088315 53884.42090453408 1.5233077233135037 1.4798199341356322 1.3844914487115974 1.4437973218640707 1.2221453841210006 1.2333836203012283 1.1725569041545034 1.1145399470129946 1.0384071746825607 1.0 15.717580599974772 -6.5125010725800205 0.4156611074237303 0.98851030087338 1.5937486655766329 0.9557980375153614 0.03728862329805014 0.2865818289227989 0.09611985994743354 0.03619459925236217 0.07284942486215443 3.072549776961102e-07 6.5125010725800205 0.6052383647032529 SIYGEKFEDENFILK ddPTM_PC-9_Lapatinib_30min_R1 1 SIYGEKFEDENFILK 15 1 P62937;F8WE65;C9J5S7;P62937-2 P62937 PPIA Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase 0 70.27199999999999 0.031180000000000003 5796800.0 37610.0 16038.0 36148.0 24164.0 25311.0 20736.0 19383.0 22099.0 20501.0 20506.0 False True 37073.67450317072 16000.864996371787 33176.050975315185 25941.101168740974 23822.256743340637 19849.169617976906 20386.556898252602 23125.800216365868 18191.9614948994 24050.434777472514 1.5414970600821225 0.6653046044456306 1.3794366414693853 1.0786125659998216 0.9905125193684396 0.8253143779574897 0.8476585594763641 0.961554351525789 0.7564088409719474 1.0 14.553775354444301 -6.378051821897578 2.5545325243366364 0.8754870439835899 1.1499909110983413 0.27471880850932806 0.2204081097153197 0.40881388811371605 5.204626361360565 0.07011380682018739 0.08208257238725622 4.1874359583816734e-07 6.378051821897578 0.2745038671147514 SIYYITGESK ddPTM_PC-9_AZD4547_30min_R2 2 SIYYITGESK 10 0 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 0 ; 150.35 0.00073901 10173900.0 46258.0 49122.0 64384.0 66271.0 63893.0 58996.0 55405.0 73444.0 61952.0 63496.0 False True 60967.08177382792 64999.72586693452 63530.2260922417 50993.2448267434 55022.559823459625 55306.970793736684 60335.93766629296 62094.91737522356 65226.656242485304 61273.02436667822 0.9950068958401753 1.0608212429331785 1.0368384252106706 0.8322299307699064 0.8979899456926799 0.902631645253241 0.9847063742965024 1.013413619076918 1.064524836445925 1.0 15.902964442405812 -9.801434680403393 9.21002598634076 1.0000051288234524 0.973327056758547 0.007708545160110214 0.0726596991638941 0.0 0.0 0.07831831354678323 0.018994981127860577 1.5796661778727047e-10 9.801434680403393 -0.026678072064905356 SIYYITGESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SIYYITGESK 10 0 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 0 99.53 0.019986 6830000.0 43513.0 29452.0 35942.0 50834.0 52832.0 38839.0 46903.0 44950.0 35068.0 35629.0 False True 50878.89147907548 32375.799918512905 36798.993590794045 47985.93578605162 42479.94885768533 36802.21446784811 42460.008291686325 43770.110128461834 35580.80315786196 42088.25566099119 1.2088619658864062 0.769235964048752 0.8743292638972584 1.1401265039959019 1.0093064725668157 0.8744057906385899 1.0088326927513815 1.0399601846419462 0.8453855499371395 1.0 15.361130098271282 -4.727196800191324 24.51693237075528 0.9572408994005493 1.2088644341181687 0.35252247049729035 0.10444328179084521 5286.687256450464 3784865.401499247 0.026631075033407784 5.123079701075291 1.8741450483112912e-05 4.727196800191324 0.25162353471761933 SIYYITGESK ddPTM_PC-9_Lapatinib_30min_R1 2 SIYYITGESK 10 0 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 0 ; 173.32 0.0077777 56050000.0 246240.0 206084.0 247237.0 213845.0 245042.0 190698.0 231195.0 208557.0 226328.0 201543.0 False True 242728.57244511394 205606.8251597635 226910.12822241915 229571.8746660077 230629.11133110782 182542.29107875013 243165.1458541768 218247.31959476013 200836.55730050188 236379.4390108328 1.0268599225924644 0.8698168758677058 0.9599402095713592 0.9712006916789699 0.9756733170034241 0.7722426783083471 1.028706840458459 0.923292315558623 0.8496363226045982 1.0 17.85074502548877 -4.738041907725162 24.69510964160557 0.9275807494196745 1.0268604094486016 0.1398133752225863 0.07368451185943817 3583.5040998950076 3782018.638220612 0.01768056643944206 1.006624690687677 1.8279238201064575e-05 4.738041907725162 0.09927966002892707 SKDHFGLEGDEESTMLEDSVS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 SKDHFGLEGDEESTMLEDSVSPK 23 1 Q9Y490 Q9Y490 TLN1 Talin-1 1 SKDHFGLEGDEEST(0.001)MLEDS(0.088)VS(0.91)PK 49.485 0.016953 10213000.0 20599.0 15891.0 39370.0 51282.0 48178.0 43548.0 29520.0 47027.0 39614.0 45220.0 True False 27149.05351418307 21027.454984557964 38847.92807609899 39459.727199001936 41489.316312814204 40824.93667580251 32147.22281218242 39760.057722954 41707.91516641614 43636.86156389679 0.6221587103469649 0.4818736781463484 0.8902548598554588 0.9042750964393179 0.9507859829025979 0.93556078995331 0.7366987830944196 0.9111575924114972 0.9557954828017106 1.0 15.413259723900657 -5.2700864440834 24.244781918717166 0.9032880216881299 0.5520161915169484 0.7940727381976855 0.0729606212737754 155.39123109868274 435690.08054083015 0.019145841378472594 0.0409220231177947 5.369249135902887e-06 5.2700864440834 -0.3512718301711816 SKDHFGLEGDEESTMLEDSVS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 SKDHFGLEGDEESTMLEDSVSPK 23 1 Q9Y490 Q9Y490 TLN1 Talin-1 1 SKDHFGLEGDEES(0.004)T(0.016)MLEDS(0.097)VS(0.884)PK 78.08800000000001 0.00042466 3853900.0 14599.0 13153.0 17097.0 10738.0 12159.0 13984.0 13997.0 14778.0 13966.0 11032.0 True False 14390.815582871295 13122.545036617918 15691.350656328525 11527.708340917914 11443.83152551376 13385.936918296167 14721.69617215301 15464.63982974138 12393.002011500166 12938.866500784015 1.1122160957452727 1.014195875335971 1.2127299292699036 0.8909364927924255 0.8844539453916103 1.03455251798796 1.1377887059319274 1.1952082378162197 0.9578120317378054 1.0 13.659423616251974 -10.136920434819261 15.325106465963549 0.9999825928033749 1.049692564722156 0.017289809424197 0.11039233473940059 0.0 0.0 0.11218264198545311 0.027208287192169046 7.295911631973556e-11 10.136920434819261 0.049709971918781126 SKDYDVYS(ph)DNDICSQESEDNFAK ddPTM_PC-9_AZD4547_30min_R2 1 SKDYDVYSDNDICSQESEDNFAK 23 1 A0A0C4DGZ1;Q8N5P1 A0A0C4DGZ1 ZC3H8 Zinc finger CCCH domain-containing protein 8 1 S(0.005)KDY(0.013)DVY(0.136)S(0.844)DNDICS(0.001)QESEDNFAK 78.27199999999999 0.00012798 9695500.0 72499.0 65187.0 95279.0 108150.0 93798.0 101470.0 89804.0 98614.0 85357.0 102070.0 True False 95552.17392712056 86257.42294873699 94015.53820580723 83217.68840084359 80775.76677133444 95125.06485932009 97796.38202659978 83375.47222428357 89868.79676023089 98496.56036769004 0.9701067079948984 0.8757404586184121 0.9545058005563337 0.8448791317198281 0.8200871834488084 0.9657704239032909 0.9928913422105657 0.8464810538869675 0.9124054324815862 1.0 16.587785724147693 SKDYDVYS(ph)DNDICSQESEDNFAK ddPTM_PC-9_Lapatinib_30min_R1 3 SKDYDVYSDNDICSQESEDNFAK 23 1 A0A0C4DGZ1;Q8N5P1 A0A0C4DGZ1 ZC3H8 Zinc finger CCCH domain-containing protein 8 1 S(0.001)KDY(0.002)DVY(0.085)S(0.798)DNDICS(0.114)QES(0.001)EDNFAK;S(0.002)KDYDVY(0.005)S(0.993)DNDICSQESEDNFAK;S(0.008)KDY(0.007)DVY(0.085)S(0.882)DNDICS(0.018)QESEDNFAK 111.15 3.6321e-07 26341000.0 196006.0 214030.0 256705.0 238080.0 260145.0 235485.0 219642.0 235971.0 254659.0 208425.0 True False 193210.91849690158 213534.42668496387 235599.70580995633 255589.197411598 244843.7825647486 225413.85549234634 231013.98804344013 246935.074114488 225976.6217418461 244450.98354114452 0.7903871594134186 0.8735265597694887 0.9637911960796083 1.045564201498002 1.0016068621116345 0.9221229230783848 0.9450319434061808 1.010161916869217 0.9244250870596765 1.0 17.899185684434435 -5.04535036403943 2.375243785717624 0.9778268411498917 0.78813044478923 0.7258863850250821 0.0373275993254947 0.1922011075590476 1.870371846783402 0.01063987922048779 0.059408834097829225 9.008440946966141e-06 5.04535036403943 -0.1896963963606617 SKEFVS(ph)SDESSSGENK ddPTM_PC-9_Lapatinib_30min_R1 1 SKEFVSSDESSSGENK 16 1 Q08945 Q08945 SSRP1 FACT complex subunit SSRP1 1 S(0.023)KEFVS(0.769)S(0.162)DES(0.008)S(0.024)S(0.014)GENK 73.405 0.006882899999999999 5172400.0 26714.0 20387.0 24233.0 20896.0 27323.0 24944.0 20449.0 18668.0 21477.0 25435.0 True False 26333.0534612524 20339.795154073545 22240.656282085132 22432.761547012567 25715.91485908482 23877.203267304027 21507.749162274544 19535.383430884565 19058.034097163756 29831.405859992854 0.882729214467491 0.6818248945267247 0.7455450268239708 0.7519847255035784 0.8620416677570214 0.8004048947396724 0.7209767204139301 0.6548596309060858 0.638858060750085 1.0 14.864544348487984 -7.270710450471103 23.17292842831054 0.7249118952716103 0.7824994348486553 0.0 0.10822534580794987 803.8864755199412 2009287.3491129219 0.043187963872862924 0.029625374837117788 5.3615399891301965e-08 7.270710450471103 0.05758753957704499 SKENMAQESSIQEQGVTSNTS(ph)DSESSSK ddPTM_PC-9_Lapatinib_30min_R1 1 SKENMAQESSIQEQGVTSNTSDSESSSK 28 1 Q92796-2;Q92796-3 Q92796-2 DLG3 Disks large homolog 3 1 SKENMAQESSIQEQGVTS(0.001)NT(0.318)S(0.601)DS(0.069)ES(0.008)S(0.003)S(0.001)K 141.78 1.274e-16 0.0 3254.9 3037.1 2916.6 3938.5 2863.0 3032.9 4161.3 4939.4 3807.6 3516.7 True False 3208.4845291244437 3030.0677815488693 2676.8084064015798 4228.150428450848 2694.603968874569 2903.189937035214 4376.751752602722 5168.902556166232 3378.747992194473 4124.5569092917995 0.7778979899383547 0.7346407985601398 0.648992962218867 1.0251162782905658 0.6533075014201324 0.7038792289409098 1.061144711748983 1.2532019001899892 0.8191784151608702 1.0 12.010023427268449 -7.267282868748631 24.475986721513458 1.0544814424981066 0.7587982617484673 0.4803524900276025 0.13998044373610288 298.5012815135095 1250291.9005298545 0.056283329796367486 0.03910512141534784 5.40402228453594e-08 7.267282868748631 -0.2956831807496393 SKESVPEFPLS(ph)PPK ddPTM_PC-9_AZD4547_30min_R2 8 SKESVPEFPLSPPK 14 1 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 SKESVPEFPLS(1)PPK;SKESVPEFPLS(1)PPK;SKESVPEFPLS(1)PPK;SKESVPEFPLS(1)PPK;S(0.001)KES(0.007)VPEFPLS(0.993)PPK;SKESVPEFPLS(1)PPK;SKESVPEFPLS(1)PPK;SKESVPEFPLS(1)PPK 152.94 3.1791999999999996e-05 2824803500.0 746640.0 785007.0 554597.0 592500.0 649368.0 676122.0 680252.0 622635.0 708806.0 713679.0 True False 984055.9889232315 1038745.161101435 547242.681412758 455908.27903374785 559214.4621075914 633843.984456621 740793.1101772608 526421.067478927 746272.0381038712 688693.3154369819 1.428874023989676 1.5082840762616407 0.7946101249226265 0.6619902775511479 0.8119934513271194 0.920357393122716 1.0756502111643427 0.7643766182700761 1.0836057521922586 1.0 19.393502148515005 -5.258887144951095 24.95602231175857 0.8775756870964427 1.4685791111583295 0.7570162694971031 0.1311976842298097 98.4573745012662 962712.0530393843 0.03503642063277414 0.08426277406106272 5.5095084698499515e-06 5.258887144951095 0.5910034240618868 SKESVPEFPLS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 SKESVPEFPLSPPK 14 1 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 SKESVPEFPLS(0.999)PPK;SKESVPEFPLS(1)PPK;SKESVPEFPLS(1)PPK;SKESVPEFPLS(1)PPK;SKESVPEFPLS(1)PPK;SKESVPEFPLS(1)PPK;SKESVPEFPLS(1)PPK;SKESVPEFPLS(1)PPK 151.11 4.7258e-05 1488414700.0 679324.0 756079.0 538363.8 715206.0 728012.0 601920.0 853632.0 715474.0 638818.0 605355.0 True False 794320.1359394082 831137.5263679671 551200.4347480804 675135.3265491358 585363.2746778688 570354.2555804001 772769.7971995142 696693.5656073662 648159.5047250792 715101.0695124561 1.1107802376536262 1.1622658136067714 0.7708007416684185 0.9441117561318035 0.818574184313498 0.7975855160855208 1.0806441636653903 0.9742588779546367 0.9063886663838769 1.0 19.44778763546021 -5.242002428367093 24.772164342380037 0.9104380773542219 1.1365230829222377 0.4901944083429355 0.0917679250676828 623.7688219906502 794982.59918146 0.024105518941995703 0.06356943880420708 5.727928281932497e-06 5.242002428367093 0.2260850055680158 SKESVPEFPLS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 7 SKESVPEFPLSPPK 14 1 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 SKESVPEFPLS(1)PPK;SKESVPEFPLS(1)PPK;SKESVPEFPLS(1)PPK;SKESVPEFPLS(1)PPK;SKESVPEFPLS(1)PPK;SKESVPEFPLS(1)PPK;SKESVPEFPLS(1)PPK 157.84 0.000933 2606163200.0 530576.0 740519.0 497899.0 619189.0 712654.0 642807.0 737158.0 665991.0 604221.0 720030.0 True False 523009.8889442772 738804.3737528505 456963.6661657207 664726.2246139525 670737.0928516727 615315.6430663037 775324.4342982039 696935.3731796795 536167.2682507979 844486.2261203321 0.6193231727970809 0.8748566298671366 0.541114410195966 0.7871368461126738 0.7942546273763598 0.7286272102899005 0.9181019302826696 0.8252773717594917 0.6349035089820383 1.0 19.68771436677082 -5.97297100426071 24.991827870245505 0.8071315166486304 0.6924158329997864 0.20249070810354686 0.1213888320769123 393.6928455581438 364017.714843893 0.03264444849714343 0.04841846085262319 1.0642140682718577e-06 5.97297100426071 -0.11471568364884399 SKESVPEFPLS(ph)PPKK ddPTM_PC-9_AZD4547_30min_R2 2 SKESVPEFPLSPPKK 15 2 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 SKESVPEFPLS(1)PPKK;SKESVPEFPLS(1)PPKK 60.333999999999996 0.016403 37658000.0 251300.0 248162.0 222260.0 226115.0 234998.0 275440.0 254570.0 266550.0 261250.0 275440.0 True False 331208.17263528414 328375.51342759264 219312.6871778959 173987.68019192564 202372.58406074773 258216.69325762472 277226.23683256435 225360.8222096534 275059.1416475543 265796.92943741044 1.2460948037899613 1.2354375730473521 0.8251136972955114 0.654588751496078 0.7613804436683765 0.9714810995152195 1.0430001483438704 0.8478684185203167 1.03484694962334 1.0 18.01996491271904 -5.255127887339603 24.061656993612885 0.8818984745891785 1.2407662839991158 0.5767546385952826 0.11914430920107631 219.4586839948639 836643.68177881 0.033515037077578705 0.0839733252304717 5.557405834198766e-06 5.255127887339603 0.35886780940993734 SKESVPEFPLS(ph)PPKK ddPTM_PC-9_Lapatinib_30min_R1 3 SKESVPEFPLSPPKK 15 2 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 SKESVPEFPLS(1)PPKK;SKESVPEFPLS(1)PPKK;SKESVPEFPLS(1)PPKK 78.08800000000001 0.024531999999999998 25239000.0 108434.0 164598.0 147326.0 158431.0 195548.0 172575.0 207234.0 208047.0 185605.0 215949.0 True False 106887.71127563958 164216.88344387105 135213.42497480614 170082.5442503232 184046.25110216005 165194.3695419735 217963.5625162504 217713.6231329145 164700.21039270287 253275.49691604424 0.42202152429719925 0.6483725644344729 0.5338590847563383 0.6715317759566065 0.7266642582609075 0.652231943292691 0.8605789552097926 0.859592127086349 0.6502808696385568 1.0 17.950347985014105 -4.690011907425571 0.15157383127100443 1.0493864457216167 2.6311653850969734e-13 0.7013640652086925 0.08726649205300148 14.339412468465625 0.3632225235859622 0.4055618134938885 3.0273060077935514 2.0416819653505674e-05 4.690011907425571 -1.0493864457213535 down SKESVPEFPLS(ph)PPKKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKESVPEFPLSPPKKK 16 3 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 SKESVPEFPLS(1)PPKKK 65.219 0.023805 14750000.0 117080.0 37249.0 52580.0 123730.0 131040.0 170380.0 137600.0 217590.0 154290.0 130540.0 True False 136899.3315645932 40946.834549935054 53833.70661076042 116797.80923807231 105363.65267851093 161444.9728631522 124565.53186226962 211878.49305566176 156546.19936199774 154205.8686459289 0.8877699193078499 0.26553356827134006 0.3491028394928837 0.7574148134806141 0.6832661662211815 1.0469444145076279 0.8077872324579536 1.3739975976021679 1.0151766643942877 1.0 17.234498145690196 -6.611423425716039 1.128866325488984 1.1016793271225858 0.4938287365606165 0.5496260603609101 0.21066805574656053 0.3390131705407383 0.918416742218934 0.10172851796682064 0.1064690803979587 2.446676633121556e-07 6.611423425716039 -0.6078505905619693 SKESVPEFPLS(ph)PPKKK ddPTM_PC-9_Lapatinib_30min_R1 2 SKESVPEFPLSPPKKK 16 3 P16949;A2A2D0;P16949-2 P16949 STMN1 Stathmin 1 SKESVPEFPLS(1)PPKKK;SKESVPEFPLS(1)PPKKK 72.321 0.013597999999999999 80370000.0 2543500.0 663140.0 874380.0 872360.0 787570.0 915660.0 524620.0 546130.0 1072950.0 725920.0 True False 2507229.22357922 661604.5400732018 802491.8516044081 936516.2645076512 741246.6810221944 876499.3563077127 551782.2566146249 571505.1935455854 952103.072335607 851394.3047724013 2.944850828253384 0.7770835867290243 0.9425619211992896 1.0999794798463034 0.8706267787642153 1.0294869855184463 0.6480924919531026 0.6712579475127718 1.1182868701360735 1.0 19.6994679139761 -4.75938552155009 24.999987958461276 0.8979415803985333 2.9448534356014933 0.9377432406599882 0.15755815306604207 12.10963100535821 147364.12057633398 0.03997241431811354 0.2549287849441938 1.740261364166597e-05 4.75938552155009 2.0469118552029597 SKETSSPGTDDVFTPAPS(ph)DSPSSQR ddPTM_PC-9_AZD4547_30min_R2 1 SKETSSPGTDDVFTPAPSDSPSSQR 25 1 P19634 P19634 SLC9A1 Sodium/hydrogen exchanger 1 1 SKETSSPGTDDVFT(0.001)PAPS(0.548)DS(0.385)PS(0.055)S(0.012)QR 115.66 4.0503e-09 27091000.0 34303.0 66862.0 81701.0 76284.0 72612.0 50440.0 54741.0 79785.0 56904.0 49574.0 True False 45210.64045327553 88473.83394232679 80617.59135751486 58697.90237605132 62531.07717435478 47285.978826294646 59612.84295263139 67456.06152690758 59911.82926818158 47838.42934915123 0.9450694989023021 1.8494301578464456 1.6852056485618128 1.227003126453874 1.3071306484159106 0.9884517420330735 1.246128766426339 1.410081025749739 1.2523786855733081 1.0 15.545882402710285 -5.783322808649307 23.482919440426436 1.2185545291752464 1.528854461752827 0.21642644257597432 0.2480396497478337 159.29154448618945 170933.6576406611 0.06890948201598783 0.1023384980734741 1.6469377768573092e-06 5.783322808649307 0.3102999325775806 SKETSSPGTDDVFTPAPS(ph)DSPSSQR ddPTM_PC-9_Lapatinib_30min_R1 1 SKETSSPGTDDVFTPAPSDSPSSQR 25 1 P19634 P19634 SLC9A1 Sodium/hydrogen exchanger 1 1 SKETSSPGTDDVFTPAPS(0.748)DS(0.224)PS(0.024)S(0.005)QR 184.31 5.0732e-21 43068000.0 283780.0 267680.0 107410.0 56134.0 86643.0 71887.0 40176.0 38485.0 124550.0 25751.0 True False 279733.24516112194 267060.2034062099 98579.16441459037 60262.28161753458 81546.82908669196 68812.56058678184 42256.11669732221 40273.153596399825 110521.86743035541 30202.02603894934 9.262068869166939 8.842459875433585 3.263991769540892 1.9953059288081776 2.7000449897476075 2.2784087563542696 1.3991152991798494 1.3334586740790995 3.659418983608035 1.0 14.882357712487304 -5.297051313282494 3.179111549953727 2.0936460305430673 9.325689669224799 0.9362778551898667 0.7207574312688477 0.052156197998800856 1.0629662285620627 0.1918657490350794 0.517812769479154 5.046016737390788e-06 5.297051313282494 7.2320436386817315 SKETSSPGTDDVFTPAPSDS(ph)PSSQR ddPTM_PC-9_AZD4547_30min_R2 1 SKETSSPGTDDVFTPAPSDSPSSQR 25 1 P19634 P19634 SLC9A1 Sodium/hydrogen exchanger 1 1 SKETSSPGTDDVFTPAPS(0.013)DS(0.446)PS(0.446)S(0.096)QR 139.57 6.102899999999999e-07 30501000.0 23559.0 41467.0 38404.0 43952.0 39412.0 23402.0 36947.0 39973.0 28120.0 24189.0 True False 31050.271942358337 54870.39681861842 37894.73786727215 33819.545451630845 33940.32410063995 21938.66924054216 40235.211424176996 33796.091338159786 29606.365791882217 23342.150472558584 1.3302232790788298 2.3507001586304126 1.6234467304896278 1.4488615987369997 1.4540358713110324 0.9398735247780028 1.7237148510150413 1.4478568021353058 1.268364961775392 1.0 14.51064985975403 -1.5228787452812442 0.11825054765124404 0.8717870394974441 3.9546372190844186 0.28090548679031724 0.32017769820088704 122.86712259793335 1.005337210831252 2.353285998225287 62.25668835781868 0.02999999999993737 1.5228787452812442 3.0828501795869743 SKETSSPGTDDVFTPAPSDS(ph)PSSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SKETSSPGTDDVFTPAPSDSPSSQR 25 1 P19634 P19634 SLC9A1 Sodium/hydrogen exchanger 1 1 SKETSSPGTDDVFTPAPS(0.08)DS(0.703)PS(0.161)S(0.057)QR;SKETSSPGTDDVFTPAPS(0.093)DS(0.847)PS(0.045)S(0.015)QR;SKETSSPGTDDVFTPAPS(0.063)DS(0.81)PS(0.106)S(0.021)QR 198.69 1.0651e-25 35068600.0 185973.0 168798.0 180826.0 135680.0 361531.0 149933.0 137336.0 144742.0 141626.0 146107.0 True False 217454.55576581907 185555.14989288125 185137.5776264237 128078.28948049525 290691.5958219982 142070.2495380382 124326.53985346398 140942.67586682586 143697.01231993188 172595.04251762433 1.2599119452901666 1.0750896850002718 1.0726703092153913 0.7420739762407527 1.6842407034507645 0.8231421219617641 0.72033667966314 0.8166090625252673 0.8325674377655339 1.0 17.397031500726833 -6.926275152436801 24.999999932646492 0.8191078073134781 1.1449596618350588 0.338074964333421 0.22784379893084872 47.59916992334289 16139.4883157972 0.07840585766194155 0.06914746496196064 1.1850177282009045e-07 6.926275152436801 0.3258518545215807 SKETSSPGTDDVFTPAPSDS(ph)PSSQR ddPTM_PC-9_Lapatinib_30min_R1 1 SKETSSPGTDDVFTPAPSDSPSSQR 25 1 P19634 P19634 SLC9A1 Sodium/hydrogen exchanger 1 1 SKETSSPGTDDVFTPAPS(0.223)DS(0.642)PS(0.13)S(0.006)QR 160.1 2.8373e-08 37094000.0 411450.0 379180.0 140270.0 74683.0 120400.0 92501.0 62938.0 68378.0 185320.0 41206.0 True False 405582.6475493114 378302.0320067501 128737.54205785839 80175.4369551847 113318.30871550742 88544.94786036272 66196.6216820009 71555.09150616163 164447.31009388604 48328.4021964563 8.392221325683531 7.827737206559029 2.6638071239048355 1.658971398004621 2.344755952304513 1.8321513610242077 1.3697250203495202 1.4806012252440746 3.402705295850733 1.0 15.560583677618336 -5.2742882420543085 3.553545175943892 1.8980299320621372 8.34340877862578 0.9412617065019261 0.6170763918037351 0.04508286914338053 1.2318417940075768 0.16029823052532127 0.42709300953174684 5.317552151977298e-06 5.2742882420543085 6.445378846563642 SKETSSPGTDDVFTPAPSDSPS(ph)SQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKETSSPGTDDVFTPAPSDSPSSQR 25 1 P19634 P19634 SLC9A1 Sodium/hydrogen exchanger 1 1 SKETSSPGTDDVFTPAPS(0.107)DS(0.252)PS(0.596)S(0.045)QR 84.93799999999999 5.0002e-06 5626900.0 17962.0 17777.0 20284.0 17195.0 38391.0 17398.0 15429.0 17538.0 16785.0 16649.0 True False 21002.611834328916 19541.783075899904 20767.647487498372 16231.619896942151 30868.559142099446 16485.618252571414 13967.453423713374 17077.646083047017 17030.448870899778 19667.33190658852 1.0678932930039728 0.9936163770823151 1.0559463574487828 0.825308688236689 1.5695346622872897 0.838223422011237 0.710185473558531 0.8683255138093255 0.8659257367388309 1.0 14.263513632731824 SKGHYEVT(ph)GSDDETGKLQGSGVSLASK ddPTM_PC-9_AZD4547_30min_R2 1 SKGHYEVTGSDDETGKLQGSGVSLASK 27 2 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(0.003)KGHY(0.012)EVT(0.376)GS(0.376)DDET(0.063)GKLQGS(0.131)GVS(0.039)LASK 55.881 0.0017994 80803000.0 26212.0 24632.0 130490.0 264550.0 186130.0 150860.0 91108.0 164720.0 94025.0 165220.0 True False 34546.87075653028 32593.812294986583 128759.61733934852 203562.084756756 160289.06233766658 141426.7003516017 99216.43550041717 139266.30888904192 98994.96954415806 159435.69808905417 0.21668215569410204 0.2044323365823696 0.8075959078338198 1.2767660392031819 1.0053524038771777 0.8870453859875634 0.6222974947868888 0.8734951491933352 0.6209084334981465 1.0 17.282615163300697 -5.288996060364514 4.907883346992733 0.894828542161605 0.20312044311430144 0.6958922032212054 0.17933554158777518 0.10261019323560809 6.803074469438645 0.05116172649026698 0.1188569969833983 5.140483146713687e-06 5.288996060364514 -0.6917080990473036 SKGHYEVTGS(ph)DDETGK ddPTM_PC-9_Lapatinib_30min_R1 1 SKGHYEVTGSDDETGK 16 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 SKGHYEVT(0.003)GS(0.994)DDET(0.003)GK 86.539 0.0021046 9760700.0 11843.0 9759.7 26441.0 11146.0 22099.0 23941.0 12574.0 17916.0 24594.0 13426.0 True False 11674.116648259782 9737.102014284184 24267.123045211596 11965.714021966021 20799.180268305663 22917.09923919682 13225.020194945493 18748.442765573593 21823.96473369863 15746.666210979522 0.7413706807425616 0.6183595869641849 1.5410959196106602 0.7598887194054325 1.3208624600045962 1.4553619751727285 0.839861594686259 1.1906293379420878 1.3859419156596875 1.0 13.942758801813728 -5.237415176087361 24.956727544268194 1.180268935329214 0.679864988534433 0.40606062127643405 0.24509326439750437 736.6608825786684 765252.5075675442 0.059958464700360155 0.15845869208904492 5.788750398682266e-06 5.237415176087361 -0.500403946794781 SKGHYEVTGS(ph)DDETGKLQGSGVSLASK ddPTM_PC-9_AZD4547_30min_R2 1 SKGHYEVTGSDDETGKLQGSGVSLASK 27 2 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(0.001)KGHY(0.002)EVT(0.175)GS(0.811)DDET(0.009)GKLQGS(0.001)GVSLASK 62.1 0.00040265 72197000.0 51277.0 64961.0 255910.0 526490.0 397180.0 330690.0 159100.0 335860.0 190920.0 342530.0 True False 67582.0193721426 85958.37286840798 252516.46619137673 405115.86468941416 342038.4128258443 310011.90202354 173259.59178246043 283960.5542950084 201011.64142909483 330538.12895801826 0.2044605854858161 0.2600558463236342 0.7639556349744114 1.225625212941373 1.0347926089618746 0.9379005774638323 0.5241742982228419 0.8590856225578573 0.6081345049745391 1.0 18.334457176686563 -5.2907689119849755 4.021616856128121 0.8790228472816829 0.2171395358315523 0.6438924936987533 0.19108403289095724 0.13470309243180173 4.963121975241621 0.05493516002768215 0.13525621001322335 5.119541738013058e-06 5.2907689119849755 -0.6618833114501306 SKGHYEVTGS(ph)DDETGKLQGSGVSLASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SKGHYEVTGSDDETGKLQGSGVSLASK 27 2 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(0.001)KGHY(0.003)EVT(0.043)GS(0.798)DDET(0.11)GKLQGS(0.034)GVS(0.011)LASK;S(0.002)KGHY(0.004)EVT(0.156)GS(0.601)DDET(0.086)GKLQGS(0.124)GVS(0.025)LASK 61.903999999999996 0.00042841 49893000.0 36842.0 23200.0 82522.0 119590.0 172495.0 168890.0 126345.0 141908.0 168015.0 100615.0 True False 43078.62293733133 25503.142676541454 84489.63744642762 112889.76001601144 138695.843015718 160033.111086147 114376.68694141322 138183.0653639545 170471.90152184817 118855.70303209845 0.3624447278368916 0.2145723093291873 0.7108589263370068 0.9498051598375904 1.1669262768002095 1.346448735765991 0.962315513884297 1.1626119894864149 1.4342761615385853 1.0 16.858851603958037 -5.624521407336703 1.611713688184002 1.1832913474626134 0.26065577448462934 0.8552887580087805 0.14366539085267419 0.13572705878731703 0.6956634774270221 0.04449808455605589 0.1165387558066363 2.3739884007056813e-06 5.624521407336703 -0.922635572977984 down SKGHYEVTGS(ph)DDETGKLQGSGVSLASK ddPTM_PC-9_Lapatinib_30min_R1 1 SKGHYEVTGSDDETGKLQGSGVSLASK 27 2 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(0.011)KGHY(0.023)EVT(0.197)GS(0.673)DDET(0.061)GKLQGS(0.027)GVS(0.007)LAS(0.002)K 48.961000000000006 0.0075218 30841000.0 31239.0 18531.0 56344.0 22877.0 38309.0 43137.0 18880.0 25744.0 60885.0 19503.0 True False 30793.526131468996 18488.092608041243 51711.61381412967 24559.45089543483 36055.73993839184 41292.131067258415 19857.514019450522 26940.160223092567 54027.49015252667 22874.067563886016 1.3462199517188784 0.8082555739771693 2.2607091488954456 1.07368096324983 1.5762714627684882 1.8051940675584592 0.8681234312170135 1.1777599304474458 2.361953771520122 1.0 14.481425314273979 SKIETEIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKIETEIK 8 1 Q9HB71;B2ZWH1;Q9HB71-2 Q9HB71 CACYBP Calcyclin-binding protein 0 77.192 0.030968 5491000.0 18095.0 20423.0 17971.0 21991.0 24010.0 21571.0 24245.0 24395.0 18933.0 18009.0 False True 21158.12610745917 22450.4604690951 18399.496795397023 20758.91556578396 19305.412857227144 20439.77878642477 21948.338081400638 23754.65709863907 19209.859307283015 21273.889140834435 0.9945584452091056 1.0553058879113117 0.8648863719083633 0.9757931626116259 0.9074698438740627 0.9607918256559577 1.0317031331742545 1.1166109281373895 0.9029782556500404 1.0 14.376796180186851 -7.2535697968490345 20.423054391760814 1.022540664311178 0.9581759491462402 0.12116241209971723 0.06788637003071585 90.22396126677586 234150.71078880937 0.026180913518089932 0.01978143688369269 5.577379590946707e-08 7.2535697968490345 -0.06436471516493791 SKLS(ph)NPEK ddPTM_PC-9_AZD4547_30min_R2 1 SKLSNPEK 8 1 Q9Y2I1;C9J715;Q9Y2I1-4;Q9Y2I1-3 Q9Y2I1 NISCH Nischarin 1 S(0.005)KLS(0.995)NPEK 57.174 0.038985 9338700.0 31694.0 38773.0 46804.0 54324.0 53403.0 43765.0 47719.0 45325.0 45059.0 47545.0 True False 41772.0327238467 51305.61400265971 46183.348378809664 41800.44109743347 45988.91525287924 41028.3676314985 51965.898556047905 38321.06271488485 47440.72675022834 45880.46402157169 0.9104535800729189 1.1182453163188861 1.0066015975142615 0.9110727624241134 1.0023637779961545 0.894244827432611 1.1326367259846155 0.8352370345876924 1.034007126168625 1.0 15.485592361971955 -5.533829909966528 24.80706618491381 0.9696478224447416 1.026367959149976 0.033928083917380114 0.09042101101486508 515.3934367813059 1167488.3816040664 0.02278992333054646 0.039517310442587564 2.9252978369863537e-06 5.533829909966528 0.05672013670523435 SKPELPPGLSPEAT(ph)APVTPSRPEGGEPGLSK ddPTM_PC-9_AZD4547_30min_R2 1 SKPELPPGLSPEATAPVTPSRPEGGEPGLSK 31 2 Q9BRP8-2;Q9BRP8 Q9BRP8-2 WIBG Partner of Y14 and mago 1 SKPELPPGLS(0.175)PEAT(0.64)APVT(0.146)PS(0.036)RPEGGEPGLS(0.003)K 54.732 0.00088689 5747500.0 25435.0 21641.0 24175.0 28626.0 29061.0 26990.0 22057.0 24999.0 20697.0 24088.0 True False 33522.80091913425 28636.03003717948 23854.42370433562 22026.717967291257 25026.381779374242 25302.311033340455 24020.030269929124 21135.978969871096 21791.001166237067 23244.686451816568 1.442170492969349 1.2319387528215757 1.0262312530557451 0.9476022837713896 1.0766495745705547 1.0885202123844129 1.03335574432117 0.9092821713763888 0.937461609190005 1.0 14.504613344986442 -4.972113497120708 1.959789010766448 1.0011959713969336 1.489775632280922 0.8686397217318161 0.05516351425136725 0.1919744640149289 1.0722491985825617 0.017221226918006906 0.1492069289561958 1.0663174168556892e-05 4.972113497120708 0.4885796608839883 SKPIPIMPAS(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 4 SKPIPIMPASPQK 13 1 O00429-4;O00429-5;O00429-3;O00429-9;O00429-2;O00429;O00429-8;O00429-6;O00429-7 O00429-4 DNM1L Dynamin-1-like protein 1 SKPIPIMPAS(1)PQK;SKPIPIMPAS(1)PQK;SKPIPIMPAS(1)PQK;SKPIPIMPAS(1)PQK 147.09 0.0005197 191846000.0 737261.0 825089.0 781647.0 635392.0 675861.0 864012.0 871295.0 928364.0 875696.0 875478.0 True False 971694.6620185504 1091782.883755203 771281.8500609224 488912.1911085413 582029.3663600599 809985.1930544107 948838.5670779286 784906.6754824371 921983.5027911841 844827.7816947629 1.1501689256351002 1.2923141347992098 0.9129456520874539 0.5787122555649877 0.6889325599502453 0.9587577617648223 1.1231147787002405 0.929072992732174 1.0913271589407765 1.0 19.68829775214246 -5.272029015824537 22.485213929910437 0.897399217300416 1.2212415169098585 0.37161461898457293 0.16100144150861984 179.5728592869422 381294.83164535067 0.047161605555795086 0.10024156558470863 5.34528645594094e-06 5.272029015824537 0.32384229960944244 SKPIPIMPAS(ph)PQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SKPIPIMPASPQK 13 1 O00429-4;O00429-5;O00429-3;O00429-9;O00429-2;O00429;O00429-8;O00429-6;O00429-7 O00429-4 DNM1L Dynamin-1-like protein 1 SKPIPIMPAS(1)PQK;SKPIPIMPAS(1)PQK 96.15299999999999 0.005079600000000001 434660000.0 866600.0 1221170.0 1049560.0 1029400.0 1104870.0 836840.0 1158030.0 860930.0 827850.0 853700.0 True False 1013298.2638698029 1342399.6871686247 1074585.490878467 971726.0553598311 888378.654875658 792954.6372273759 1048333.0149888393 838331.4997307349 839955.7401116702 1008469.0521145171 1.0047886563748885 1.3311263090859708 1.0655611975650812 0.9635655683457566 0.8809181134641084 0.7862954599992342 1.0395291881200885 0.8312912508053225 0.8329018509298675 1.0 19.943735380547245 -5.728341251872559 2.5497111377345494 0.8913574149519834 1.1725315273864303 0.5185483201080971 0.10433871683746117 0.19567266784378082 2.5880165979694625 0.02920898980494916 0.05464452936817837 1.8692128077565518e-06 5.728341251872559 0.2811741124344469 SKPIPIMPAS(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 6 SKPIPIMPASPQK 13 1 O00429-4;O00429-5;O00429-3;O00429-9;O00429-2;O00429;O00429-8;O00429-6;O00429-7 O00429-4 DNM1L Dynamin-1-like protein 1 SKPIPIMPAS(1)PQK;SKPIPIMPAS(1)PQK;SKPIPIMPAS(1)PQK;SKPIPIMPAS(1)PQK;SKPIPIMPAS(1)PQK;S(0.001)KPIPIMPAS(0.999)PQK 106.93 0.0016206 231969000.0 655209.0 887270.0 823533.0 857536.0 938242.0 913417.0 973517.0 941658.0 835043.0 775170.0 True False 645865.5995093843 885215.580828708 755825.2956693112 920602.0580962386 883056.4502147451 874352.2841890241 1023920.9468047349 985410.8683715397 740991.6639473807 909157.1016509002 0.7104004339146491 0.9736662445041481 0.8313472933300964 1.0125885354957422 0.9712913737474415 0.9617174882111403 1.1262310385580665 1.0838730364446074 0.8150314864195034 1.0 19.794170086996004 -3.826093866909976 0.6887178161169502 1.004220911970214 1.51459844541097e-12 0.41387904830920685 0.0925792258498497 10.045596285432296 1.3536501727118169 0.03761819996262542 10.6692733287057 0.0001492471797014418 3.826093866909976 -1.0042209119686993 SKPIPIMPAS(ph)PQKGHAVNLLDVPVPVAR ddPTM_PC-9_AZD4547_30min_R2 2 SKPIPIMPASPQKGHAVNLLDVPVPVAR 28 2 O00429-4;O00429-5;O00429-3;O00429-9;O00429-2;O00429;O00429-8;O00429-6;O00429-7 O00429-4 DNM1L Dynamin-1-like protein 1 S(0.409)KPIPIMPAS(0.591)PQKGHAVNLLDVPVPVAR;S(0.035)KPIPIMPAS(0.965)PQKGHAVNLLDVPVPVAR 50.986000000000004 0.0032146 4187500.0 9806.6 6137.6 10224.9 15590.099999999999 16131.5 12187.0 9785.599999999999 12342.8 9239.1 11221.2 True False 12924.894810048436 8121.459172690392 10089.311145169027 11996.043309643928 13891.919674958745 11424.944963442747 10656.499442780903 10435.50386932777 9727.459964003521 10828.349203467462 1.1936163645248545 0.7500182179283369 0.9317497021557285 1.107836761101364 1.28292128503856 1.0550957259287725 0.9841296436365823 0.9637206626090433 0.8983326803764868 1.0 13.402525698442084 -7.46389518359443 3.3760876072008257 0.9504489337642337 1.0465116925780824 0.09881512549220184 0.13705791406877244 0.725647833164635 16.3712502726522 0.07175983434647577 0.04346660496352596 3.4364087516834974e-08 7.46389518359443 0.09606275881384874 SKPIPIMPAS(ph)PQKGHAVNLLDVPVPVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SKPIPIMPASPQKGHAVNLLDVPVPVAR 28 2 O00429-4;O00429-5;O00429-3;O00429-9;O00429-2;O00429;O00429-8;O00429-6;O00429-7 O00429-4 DNM1L Dynamin-1-like protein 1 S(0.014)KPIPIMPAS(0.986)PQKGHAVNLLDVPVPVAR;SKPIPIMPAS(1)PQKGHAVNLLDVPVPVAR 83.31200000000001 6.0089e-07 3219300.0 16038.5 13684.3 16371.400000000001 22439.0 22700.0 27521.0 23539.0 27524.0 27458.0 16606.2 True False 18753.501275185637 15042.786867611907 16761.756264880245 21181.81557821954 18252.09795331346 26077.750312048396 21309.215512398005 26801.524164088594 27859.52130456753 19616.77260539313 0.955993202981302 0.7668329123352471 0.8544604457652748 1.0797808591815017 0.930433273631133 1.3293598716069628 1.0862752982383852 1.366255535669522 1.4201888284573512 1.0 14.259800085265978 -6.456294741838441 1.0611400412313379 1.2689328646948768 0.8523764151916576 0.5345695288937882 0.14519836945316242 0.3620411048449319 0.8669777133515664 0.06713521518469381 0.08311024800476496 3.4970775095701e-07 6.456294741838441 -0.41655644950321913 SKPLAAS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 SKPLAASPK 9 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 SKPLAAS(1)PK 55.898999999999994 0.041988 43913000.0 89049.0 133980.0 69804.0 101750.0 113510.0 91996.0 130160.0 124150.0 90846.0 88849.0 True False 87779.14493041331 133669.77754170672 64064.98457123227 109233.0344280499 106833.56496924648 88061.54553315023 136899.04792222867 129918.46223185764 80613.96682920984 104206.43126614943 0.8423582293708931 1.2827401909610179 0.614789162173748 1.0482369763634092 1.0252108595522975 0.8450682406370467 1.313729356805055 1.2467413062063142 0.773598767846842 1.0 16.66908479302694 -7.232864842388821 24.932935501318067 1.1040792664634327 0.9520994744497154 0.09203525456168549 0.21107903169361697 1615.6889043957938 1409784.003637445 0.07865903987318616 0.06091754100055722 5.849721061003112e-08 7.232864842388821 -0.15197979201371725 SKPPPTYES(ph)EEEDK ddPTM_PC-9_AZD4547_30min_R2 1 SKPPPTYESEEEDK 14 1 O60885;O60885-2;O60885-3 O60885 BRD4 Bromodomain-containing protein 4 1 SKPPPT(0.005)Y(0.013)ES(0.982)EEEDK 84.895 0.0097742 0.0 29960.0 32393.0 39326.0 32484.0 37590.0 42133.0 38289.0 33960.0 33678.0 41585.0 True False 39486.65679328731 42863.40377035971 38804.51154484809 24995.315672797064 32371.2773506307 39498.41684948989 41696.64682437849 28712.262323165793 35458.150325000315 40129.1218074889 0.9839900554693501 1.0681370994358652 0.9669912970187747 0.6228722321088133 0.8066779409209391 0.9842831108783122 1.0390620314197123 0.7154969017489815 0.8836014527081706 1.0 15.292361963829734 -5.534257157549045 24.999289383577285 0.8573601727315991 1.0239388032721888 0.2259064483396106 0.12303966237945922 298.2787782269369 655340.3045674806 0.034896303774227144 0.06050724208673716 2.9224214203859137e-06 5.534257157549045 0.16657863054058963 SKPPPTYES(ph)EEEDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKPPPTYESEEEDK 14 1 O60885;O60885-2;O60885-3 O60885 BRD4 Bromodomain-containing protein 4 1 SKPPPT(0.002)Y(0.008)ES(0.99)EEEDK 84.94 0.0033450000000000003 4723200.0 19375.0 33283.0 14493.0 17758.0 20108.0 14790.0 19014.0 15277.0 15958.0 16133.0 True False 22654.804826306805 36587.11628031593 14838.568085008572 16763.076832212784 16167.981746485775 14014.386363693025 17212.856270561013 14875.994937319494 16191.355560430062 19057.785191242274 1.1887427945571287 1.9197989647364166 0.7786092631491837 0.8795920755742389 0.8483662495007832 0.735362804389942 0.9031928997956661 0.7805731247383111 0.8495927201378344 1.0 14.218092845110247 -5.277312820552764 24.97423877167481 0.8383197745752037 1.5542708799224358 0.7161980490577202 0.17804557758351613 311.8400768860639 490628.717955196 0.041958130117664985 0.08778962217458686 5.2806475185770595e-06 5.277312820552764 0.7159511053472322 SKPPPTYES(ph)EEEDK ddPTM_PC-9_Lapatinib_30min_R1 5 SKPPPTYESEEEDK 14 1 O60885;O60885-2;O60885-3 O60885 BRD4 Bromodomain-containing protein 4 1 SKPPPTYES(1)EEEDK;S(0.001)KPPPT(0.008)YES(0.99)EEEDK;SKPPPT(0.001)Y(0.001)ES(0.998)EEEDK;SKPPPTYES(0.999)EEEDK;SKPPPTYES(1)EEEDK 97.713 0.0012425000000000001 41830000.0 298131.0 244551.0 179904.0 212772.0 222897.0 210222.0 226877.0 214980.0 178399.0 189118.0 True False 293879.5972694707 243984.75718466882 165112.98756952237 228419.96266658444 209786.6366923628 201231.29511141687 238623.58094231313 224968.75562307448 158305.825995247 221806.79431610525 1.3249350551933579 1.099987752570631 0.7444000445460368 1.0298149944904507 0.9458079827500141 0.9072368397544871 1.0758172745702355 1.0142554754317534 0.7137104455404525 1.0 17.758944032794965 -4.929278958691342 3.8500777761974443 0.9367718724542565 1.3155234613968252 0.5421616812349033 0.11305739996590607 0.17311837737506683 4.824987221902941 0.02800345715964863 0.14355664764990003 1.1768498093179559e-05 4.929278958691342 0.37875158894256866 SKPS(ph)PQKDQALGDGIAPPQK ddPTM_PC-9_AZD4547_30min_R2 1 SKPSPQKDQALGDGIAPPQK 20 2 Q9H9J4-2;Q9H9J4;B4DP25;E5RJP3 Q9H9J4-2 USP42 Ubiquitin carboxyl-terminal hydrolase 42 1 S(0.309)KPS(0.691)PQKDQALGDGIAPPQK 46.131 0.024938 18576000.0 143070.0 119090.0 145970.0 187380.0 167510.0 152120.0 166810.0 165040.0 125370.0 162470.0 True False 188563.2839591323 157583.51356812086 144034.3424248965 144182.43599214105 144254.127933071 142607.91235241765 181655.7668462114 139536.86024191088 131996.8022520724 156781.9747520191 1.2027102239105067 1.0051124424052544 0.9186919775230191 0.9196365603902703 0.9200938319678438 0.9095938010602274 1.158652116313339 0.890005757757646 0.8419131246487409 1.0 17.258400176551213 -4.780729150154538 2.9327283001633955 0.9457984495201367 1.2469208749587577 0.4769445293029809 0.08103658934440432 0.36266368313885033 4.428094608400958 0.021347767263760586 0.2627374071816256 1.656802914451377e-05 4.780729150154538 0.301122425438621 SKPS(ph)PQKDQALGDGIAPPQK ddPTM_PC-9_Lapatinib_30min_R1 1 SKPSPQKDQALGDGIAPPQK 20 2 Q9H9J4-2;Q9H9J4;B4DP25;E5RJP3 Q9H9J4-2 USP42 Ubiquitin carboxyl-terminal hydrolase 42 1 S(0.212)KPS(0.788)PQKDQALGDGIAPPQK 48.907 0.01907 16827000.0 168330.0 113040.0 123950.0 138040.0 124570.0 115010.0 101740.0 96486.0 121350.0 105300.0 True False 165929.58333205894 112778.26282515677 113759.30946083633 148191.9220879412 117243.03751404306 110091.29040140456 107007.59938235671 100969.09179946064 107682.28512784929 123500.96469656983 1.3435488843324601 0.9131771812652821 0.9211208166699926 1.1999252188194214 0.9493289206452604 0.8914204894827213 0.8664515264740178 0.8175571101613023 0.8719145262744664 1.0 16.914162785538437 -6.491596778855629 5.9305765213306945 0.8805085340441862 1.0705384978626322 0.3679812512816557 0.12533538387715074 0.2218291612608839 23.957835218413045 0.03973892417273861 0.04364650288730454 3.224060784556194e-07 6.491596778855629 0.19002996381844606 SKPYEGSQRNST(ph)ELAPPLPVR ddPTM_PC-9_AZD4547_30min_R2 1 SKPYEGSQRNSTELAPPLPVR 21 2 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 S(0.006)KPY(0.015)EGS(0.017)QRNS(0.333)T(0.628)ELAPPLPVR 47.222 0.0295 11041000.0 10206.0 10842.0 17072.0 19350.0 11958.0 13334.0 11236.0 17172.0 15680.0 16979.0 True False 13451.295702012363 14346.464473134312 16845.61412535336 14889.156454519867 10297.838110104856 12500.222872121574 12235.982232983795 14518.461973303974 16508.812788645562 16384.57037800539 0.820973354301029 0.8756082181070171 1.028138897554914 0.9087303549018922 0.6285082777592174 0.7629264963152068 0.7467990890630463 0.8861057469528482 1.0075828909622773 1.0 14.000050223827918 -8.135884149273734 3.6972581717241586 1.003796688218199 0.827081278997573 0.3325857469272445 0.10001369165376024 0.32621415783197016 7.614662325635638 0.08817333706314245 0.029607864762868738 7.313341453501469e-09 8.135884149273734 -0.176715409220626 SKQIS(ph)SSLDK ddPTM_PC-9_Lapatinib_30min_R1 2 SKQISSSLDK 10 1 O94964-2;H0YDM2;O94964-3;O94964 O94964-2 SOGA1 Protein SOGA1;N-terminal form;C-terminal 80 kDa form 1 SKQIS(0.731)S(0.134)S(0.134)LDK;S(0.001)KQIS(0.667)S(0.166)S(0.166)LDK 66.056 0.022269999999999998 12390500.0 101304.0 112089.0 76999.0 92158.0 93042.0 89752.0 102741.0 94353.0 83721.0 80997.0 True False 99859.38638312182 111829.46480722787 70668.43944473537 98935.6067500756 87569.45248761015 85913.51618213084 108060.42626442623 98736.98483256096 74291.459358786 94997.22352828179 1.0511821574805553 1.1771866656074945 0.7439000511809332 1.0414578771412337 0.9218106512506621 0.9043792333209968 1.137511416133708 1.0393670590084751 0.7820382175345215 1.0 16.535597728145518 -5.201920753355367 24.999992631247856 0.9555673267621807 1.1141845023344457 0.24601978623524046 0.11665820367417731 372.1195906784749 156301.96676823864 0.029143540471240233 0.07710652750841447 6.281729724243073e-06 5.201920753355367 0.15861717557226496 SKQPPPAS(ph)SPTK ddPTM_PC-9_AZD4547_30min_R2 1 SKQPPPASSPTK 12 1 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 SKQPPPAS(0.482)S(0.482)PT(0.036)K 88.311 0.0038236999999999993 23688000.0 73928.0 51354.0 72398.0 98128.0 83444.0 78196.0 69232.0 84300.0 70986.0 84312.0 True False 97435.56620207401 67953.17621779557 71437.95521598718 75506.10566248713 71859.24094828471 73306.39175854363 75393.51387984466 71273.37202128602 74738.17503920874 81360.26254257545 1.1975817574468424 0.835213335038539 0.878044797097404 0.928046484891505 0.8832228252788774 0.9010097739075353 0.9266626178890657 0.8760219030019598 0.9186078400386011 1.0 16.31203671420529 -4.753593650921423 24.994813582062175 0.901046782765354 1.1975822938892704 0.8161822256529652 0.04158411422733025 107.08436432454158 341120.46755537076 0.009648019843749522 0.10213031126458719 1.7636254166674498e-05 4.753593650921423 0.2965355111239164 SKQPPPAS(ph)SPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKQPPPASSPTK 12 1 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 SKQPPPAS(0.784)S(0.215)PT(0.001)K 109.44 0.006331600000000001 7954200.0 48460.0 42030.0 47028.0 59995.0 64067.0 59590.0 58734.0 62161.0 55306.0 48617.0 True False 56663.32087137174 46202.46063340681 48149.325874683156 56633.67465641434 51513.53125880767 56464.995497800366 53170.290322663895 60529.339615023666 56114.745621327515 57430.87724803978 0.9866351270701817 0.8044881577180467 0.8383874351549554 0.9861189201728126 0.8969657739394172 0.9831818388204686 0.9258136540910785 1.0539511586006574 0.9770832052411808 1.0 15.809538978392156 -6.720413543883182 0.7737233563285364 1.006091155270354 0.8785117740799693 0.3430487707989599 0.05988642122131475 0.6991156215890936 0.9217919227721956 0.04023798532401879 0.04087568727301684 1.9036471637834339e-07 6.720413543883182 -0.1275793811903847 SKQPPPASS(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 2 SKQPPPASSPTK 12 1 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 SKQPPPAS(0.138)S(0.789)PT(0.073)K;SKQPPPAS(0.331)S(0.517)PT(0.152)K 89.23200000000001 0.0035876 131443000.0 152753.0 117572.0 155693.0 191549.0 161729.0 159182.0 150331.0 152407.0 139117.0 177625.0 True False 201325.2765402212 155574.84975422866 153628.40909200098 147390.337452549 139275.71999574758 149228.3243760353 163710.16777026418 128856.00011445 146470.44060701545 171406.40281484264 1.174549335579358 0.9076373297576543 0.8962816240765178 0.8598881665567861 0.8125467760162763 0.8706111436060844 0.9550994891778218 0.7517572155903848 0.8545214076118054 1.0 17.387061476166636 -4.620981408763957 2.1761194597121167 0.8656955880136894 1.3663760344323304 0.6457268833926004 0.06573303079389888 0.7187740337067512 2.6099074495508767 0.016783785524367833 0.8231208051925499 2.3934182114269962e-05 4.620981408763957 0.500680446418641 SKQPPPASS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SKQPPPASSPTK 12 1 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 SKQPPPAS(0.142)S(0.845)PT(0.013)K;SKQPPPAS(0.118)S(0.677)PT(0.205)K;SKQPPPAS(0.105)S(0.895)PTK 149.35 7.5763e-05 75134300.0 412497.0 418781.0 375911.0 483439.0 508599.0 462372.0 539722.0 542189.0 489419.0 368323.0 True False 482324.594912882 460354.81005278876 384874.1438904069 456353.4801603848 408942.67695846997 438124.3983606138 488595.6249111041 527957.1132467322 496575.8269852176 435097.0442567358 1.1085448666672137 1.0580508788314111 0.8845708077559494 1.048854470937537 0.9398884280104807 1.0069578824858476 1.1229578121951125 1.2134238101953245 1.1412990125766178 1.0 18.73097769069325 -7.280297884338274 5.095901506225026 1.138693877256074 1.002860750167557 0.3246262694710239 0.07693622216140825 0.19206691907359508 15.150954683735696 0.03197100081462029 0.022205364443682922 5.2444761611765236e-08 7.280297884338274 -0.13583312708851691 SKQPPPASS(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 4 SKQPPPASSPTK 12 1 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 SKQPPPAS(0.052)S(0.916)PT(0.032)K;SKQPPPAS(0.193)S(0.807)PTK;SKQPPPAS(0.064)S(0.917)PT(0.018)K;SKQPPPAS(0.207)S(0.792)PTK 132.31 0.00019611 120486800.0 301680.0 229864.0 236165.0 212459.0 230244.0 226289.0 211246.0 187702.0 229958.0 196585.0 True False 297377.9878786642 229331.7640308019 216748.4253232633 228083.94360244772 216701.50059712067 216611.14697542327 222183.2842453836 196423.32015983976 204057.70847490703 230564.45531695336 1.2897824492065064 0.9946535935712341 0.9400773637259161 0.9892415692995882 0.9398738426494426 0.9394819625499139 0.9636493358872326 0.8519236839426081 0.885035415343584 1.0 17.8148105932785 -4.716761180503985 2.629846856060226 0.9362486368285 1.4005701125400045 0.862300323444152 0.04185076920313171 0.22440194749958062 1.7309729339050717 0.011442802916065533 0.24931804384426798 1.9197241110024506e-05 4.716761180503985 0.4643214757115045 SKQPPPASSPT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 SKQPPPASSPTK 12 1 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 SKQPPPAS(0.013)S(0.104)PT(0.884)K 162.79 0.00050357 32757000.0 271320.0 210540.0 210960.0 221320.0 220790.0 211890.0 203870.0 197910.0 242790.0 183890.0 True False 267450.92704600573 210052.50756553878 193615.6831291496 237596.6111018768 207803.56628984158 202827.95863971507 214425.39105642872 207105.62110597643 215444.43350795656 215675.1414819773 1.240063760748037 0.97393007892424 0.897719050043275 1.1016411509887956 0.9635026311421545 0.9404327139697933 0.9942054034741272 0.9602665364347658 0.9989302987241113 1.0 17.718500376816593 -4.760672426588746 24.999349123960243 0.979676580407346 1.2400640622702823 0.7085820973520889 0.04979827296122399 9.999220094904453 325720.5965635388 0.012119678710728065 0.07078201318715661 1.7351122398787703e-05 4.760672426588746 0.26038748186293637 SKS(ph)ATLLYDQPLQVFTGSSSSSDLISGTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKSATLLYDQPLQVFTGSSSSSDLISGTK 29 1 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 S(0.218)KS(0.526)AT(0.252)LLY(0.004)DQPLQVFTGSSSSSDLISGTK 94.523 7.2958e-11 13473000.0 55489.0 51798.0 49817.0 39894.0 97431.0 51685.0 39244.0 55675.0 41867.0 45347.0 True False 64882.19174229359 56940.16311894374 51004.826212024585 37658.8685180931 78340.09496428576 48974.54761375755 35526.524218044426 54213.59024253862 42479.22567041767 53568.052133345525 1.2112105846369787 1.0629500392734854 0.9521501003071687 0.7030098541636325 1.4624406123499851 0.9142491776973057 0.6632035850325338 1.0120508042290988 0.7929955258532692 1.0 15.709085216606542 -6.983434927483143 24.999278757915615 0.8567322496320441 1.0635041416778306 0.19959478199075575 0.2023583152465705 410.4343545127056 619407.3245854772 0.07120531776177119 0.06278257940301012 1.0388792512416818e-07 6.983434927483143 0.2067718920457865 SKS(ph)CDDGLNTFRDEGR ddPTM_PC-9_AZD4547_30min_R2 1 SKSCDDGLNTFRDEGR 16 2 Q9P227;Q9P227-2;A0A087X0Z0 Q9P227 ARHGAP23 Rho GTPase-activating protein 23 1 S(0.179)KS(0.821)CDDGLNTFRDEGR 81.639 0.019809 14587000.0 19394.0 11130.0 26684.0 41451.0 47416.0 37313.0 23368.0 28410.0 25707.0 34793.0 True False 25560.888579740127 14727.55484098736 26330.152724984142 31895.112361566044 40833.10685973677 34979.81221144986 25447.706730185622 24019.887296853358 27065.81953811936 33574.90766016498 0.7613092741299449 0.4386476647994151 0.7842211508514023 0.9499687291592485 1.2161792751014262 1.0418438842931423 0.7579382492353988 0.7154118647168106 0.8061323596797753 1.0 15.035095811416456 -5.508785409415128 4.842529386435386 0.9223522150109359 0.5987396602664214 0.4110194229873676 0.15600633807552508 0.19462602680109137 12.45951387627839 0.047026646408098866 0.09332114837870858 3.0989501527884563e-06 5.508785409415128 -0.32361255474451445 SKS(ph)CDDGLNTFRDEGR ddPTM_PC-9_Lapatinib_30min_R1 1 SKSCDDGLNTFRDEGR 16 2 Q9P227;Q9P227-2;A0A087X0Z0 Q9P227 ARHGAP23 Rho GTPase-activating protein 23 1 S(0.159)KS(0.841)CDDGLNTFRDEGR 81.854 0.019295 30333000.0 41127.0 38139.0 48841.0 47764.0 38085.0 47253.0 38980.0 37461.0 54154.0 34936.0 True False 40540.521438231895 38050.69148875318 44825.48151171212 51276.72389603312 35844.915177990886 45232.099342123016 40998.193669395194 39201.57481810405 48054.606253098966 40974.64105070615 0.9894051637465955 0.9286400200959765 1.093981066392761 1.2514258229273598 0.8748073017560489 1.103904712335326 1.0005748096404286 0.9567277177508905 1.1727889499661839 1.0 15.322443690518249 -5.258460811857604 24.999998116680246 1.0553596970637014 0.9590225879937165 0.1256095194132678 0.10311134940312253 533.0296526052497 4473805.216294925 0.026228610825476176 0.06314538462033482 5.514919634803959e-06 5.258460811857604 -0.09633710906998483 SKS(ph)DATASISLSSNLK ddPTM_PC-9_AZD4547_30min_R2 1 SKSDATASISLSSNLK 16 1 Q9UBF8-2;A0A0B4J1S8;Q9UBF8 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 S(0.089)KS(0.729)DAT(0.051)AS(0.123)IS(0.008)LSSNLK 85.046 0.023282 7601200.0 22377.0 22278.0 31457.0 24932.0 25470.0 27162.0 31246.0 33595.0 23072.0 24718.0 True False 29492.420529485647 29478.92782996552 31039.85962636132 19184.31259556017 21933.930144202262 25463.555846150182 34026.833468477394 28403.664686300202 24291.538817578457 23852.630343573644 1.2364431135969651 1.2358774443468332 1.3013181011596087 0.8042849916017246 0.9195602257807883 1.0675365978247573 1.4265442837269675 1.190798007480659 1.0184008416548938 1.0 14.541860747431699 -1.5231373281153306 0.012972403230932902 0.018125690821713954 2.423242948229447 0.05532202012951526 0.17553544898459802 35562.6300995254 35.77423146538809 2734.375905535526 4011.2009739555933 0.029982143047187805 1.5231373281153306 2.405117257407733 SKS(ph)DATASISLSSNLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SKSDATASISLSSNLK 16 1 Q9UBF8-2;A0A0B4J1S8;Q9UBF8 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 S(0.013)KS(0.986)DAT(0.001)ASISLSSNLK;S(0.004)KS(0.987)DAT(0.008)AS(0.001)ISLSSNLK 144.72 0.00014202 13260300.0 30809.0 48199.0 40614.0 40002.0 39956.0 30527.0 39363.0 34680.0 35117.0 28522.0 True False 36024.35519451284 52983.87818390613 41582.39178945272 37760.81762823379 32126.90862654596 28926.110380287828 35634.25167655903 33769.68674649735 35630.51969016306 33692.81281997225 1.0691999919092097 1.5725572829733772 1.2341620752068443 1.1207380585882734 0.9535240883035428 0.8585246513802837 1.057621750578092 1.0022816120142848 1.0575109855192082 1.0 15.040153255383084 -5.8447796262974725 2.4950829740920475 0.9876739300794957 1.3320645701830134 0.5350430380652964 0.12666384671821845 0.19560781403300237 2.4761779230975542 0.03662041165744861 0.06261007463441645 1.429619205022749e-06 5.8447796262974725 0.3443906401035177 SKS(ph)DATASISLSSNLK ddPTM_PC-9_Lapatinib_30min_R1 1 SKSDATASISLSSNLK 16 1 Q9UBF8-2;A0A0B4J1S8;Q9UBF8 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 S(0.015)KS(0.894)DAT(0.078)AS(0.007)ISLS(0.004)S(0.001)NLK 102.5 0.007201999999999999 6688600.0 17939.0 25795.0 27355.0 22360.0 27432.0 28080.0 29012.0 26660.0 26730.0 22424.0 True False 17683.186570390313 25735.27326234007 25105.97749335362 24004.428990773384 25818.503693387054 26879.083857677062 30514.09940319376 27898.72092711499 23719.38592062146 26299.958521898185 0.6723655687771039 0.978529043721193 0.9546014102056314 0.9127173706675822 0.9816937038851123 1.0220200094725123 1.1602337462922896 1.0607895409373223 0.9018792140250693 1.0 14.682772903770488 -4.312769062409706 1.5035916092311352 1.0086936485178883 1.8946675839077172e-31 0.6450528138614758 0.07166349906884659 2.793974535548939 2.2579775128750934 0.021997726563705803 5.942758551077598 4.866659231834294e-05 4.312769062409706 -1.0086936485178883 SKS(ph)DSYTLDPDTLR ddPTM_PC-9_Lapatinib_30min_R1 1 SKSDSYTLDPDTLR 14 1 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 S(0.392)KS(0.572)DS(0.025)Y(0.003)T(0.008)LDPDTLR 121.92 0.0003147 14673000.0 45198.0 31823.0 41929.0 34477.0 40097.0 45238.0 42600.0 42675.0 47147.0 41478.0 True False 44553.468231701954 31749.31579869929 38481.75947062054 37012.55359190043 37738.573293735106 43303.276194928614 44805.61955659914 44657.83629274688 41836.80838008006 48647.41703403906 0.9158444774267761 0.6526413473604157 0.7910339709032134 0.7608328632536111 0.7757569793958241 0.8901454349493807 0.9210277192157647 0.9179898752178222 0.8600006111487162 1.0 15.570075585766329 -6.809904645223879 3.6766984110772425 0.9165840700272426 0.7706210572050578 0.5136400650829509 0.0676449061460115 0.18231589165448087 5.0659200328011975 0.023215886036372053 0.021009818742833686 1.549156718274917e-07 6.809904645223879 -0.14596301282218482 SKS(ph)EDMDNVQSK ddPTM_PC-9_Lapatinib_30min_R1 3 SKSEDMDNVQSK 12 1 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 S(0.001)KS(0.572)EDMDNVQS(0.428)K;S(0.293)KS(0.654)EDMDNVQS(0.053)K;S(0.003)KS(0.997)EDMDNVQSK 187.08 3.6726999999999994e-35 17162100.0 48412.0 47848.6 53770.4 46754.5 62263.0 79923.0 68931.0 71297.0 67443.0 60106.0 True False 47721.63600232649 47737.80950650919 49349.60527174637 50192.98189843984 58600.812753767845 76504.87959961264 72499.90989802658 74609.71890249518 59846.85913372508 70495.24201378928 0.6769483250088264 0.6771777518995027 0.700041646244626 0.7120052426888868 0.8312733041232085 1.0852488396968387 1.0284369246345049 1.058365313334212 0.8489489137723463 1.0 16.105238267489888 -6.5087979144559105 3.0542902245734056 1.0088279733486072 0.6919702492493458 0.8529187556312492 0.06104841414354796 0.09213131857160403 1.7544505539221356 0.020969817873090078 0.02253884427511381 3.098860923148787e-07 6.5087979144559105 -0.3168577240992614 SKS(ph)EEAHAEDSVMDHHFR ddPTM_PC-9_Lapatinib_30min_R1 1 SKSEEAHAEDSVMDHHFR 18 1 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 S(0.396)KS(0.604)EEAHAEDSVMDHHFR 53.861000000000004 0.018777000000000002 15355000.0 30204.0 23052.0 23764.0 16288.0 20254.0 18165.0 19758.0 20849.0 29934.0 33635.0 True False 29773.28542126478 22998.624510310652 21810.215651692757 17485.873855175178 19062.699540896097 17388.12529468319 20780.97256336352 21817.720653016506 26562.517701005712 39448.76493417968 0.754733018155107 0.5829998619395028 0.552874486389704 0.4432552928932093 0.4832267771298351 0.44077743178259954 0.5267838574423459 0.5530647331904917 0.6733421881603977 1.0 15.26769251245671 -8.709954097630868 1.7963598642642253 0.9996175309481827 0.5329572174844454 0.728708134730529 0.08445902523488154 0.3771803661465648 2.2879293413097996 0.08660092811111494 0.024413933281839266 1.9500506977408805e-09 8.709954097630868 -0.4666603134637374 SKS(ph)ISSSNPDLAVAPGSVDDEVSR ddPTM_PC-9_Lapatinib_30min_R1 2 SKSISSSNPDLAVAPGSVDDEVSR 24 1 Q96HP0;K7ESB7;K7EKT0;K7EP20 Q96HP0 DOCK6 Dedicator of cytokinesis protein 6 1 S(0.059)KS(0.235)IS(0.235)S(0.235)S(0.235)NPDLAVAPGSVDDEVSR;S(0.052)KS(0.237)IS(0.237)S(0.237)S(0.237)NPDLAVAPGSVDDEVSR 132.67 3.2068000000000004e-07 8820400.0 95934.0 66029.0 70815.0 56939.0 74400.0 79184.0 73637.0 70892.0 89113.0 63455.0 True False 94565.96356785917 65876.11390730982 64992.86405380503 61126.48400293583 70023.93827602784 75797.48490691956 77449.56355139175 74185.90112396967 79076.1555385088 74423.1122015272 1.2706531717161733 0.8851566665060536 0.8732887154438477 0.8213373802134747 0.9408896807004385 1.0184670146777894 1.04066547689741 0.9968126692026101 1.062521482901465 1.0 16.183463101427115 -6.77567381082048 6.561458825510988 1.0249506605924132 0.9417181858582403 0.06535597691394213 0.11561383817971699 0.3869809134448673 67.49475785426874 0.041044469742070065 0.03764903734894364 1.6762013618967194e-07 6.77567381082048 -0.08323247473417295 SKS(ph)LCHDEIENLLDSDHR ddPTM_PC-9_AZD4547_30min_R2 2 SKSLCHDEIENLLDSDHR 18 1 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4;P30305-3 G8JLH2 CDC25B M-phase inducer phosphatase 2 1 S(0.195)KS(0.805)LCHDEIENLLDSDHR;S(0.137)KS(0.863)LCHDEIENLLDSDHR 83.37 0.00094844 13336900.0 48433.0 50803.0 111957.0 150733.0 122120.0 130441.0 91570.0 144176.0 98897.0 128753.0 True False 63833.686531017476 67224.07624318785 110472.3770285958 115983.83565163538 105165.74594463994 122284.50364949807 99719.5526054045 121896.91203488692 104124.49351777289 124245.39665936294 0.5137710389868764 0.5410588887046862 0.8891466404302454 0.9335060997843014 0.8464357535351377 0.9842175801873695 0.8026015875566026 0.981098014995962 0.8380551418194231 1.0 16.92283287479792 -5.25988830028143 4.877305566309619 0.9076404419036782 0.5202005611826428 0.8536531235747666 0.06334801904104412 0.05363354769779252 3.903155930197226 0.014978963453342797 0.03731042119956808 5.4968223290788965e-06 5.25988830028143 -0.3874398807210354 SKS(ph)LCHDEIENLLDSDHR ddPTM_PC-9_Lapatinib_30min_R1 1 SKSLCHDEIENLLDSDHR 18 1 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4;P30305-3 G8JLH2 CDC25B M-phase inducer phosphatase 2 1 S(0.139)KS(0.861)LCHDEIENLLDSDHR 102.39 0.00019678 5322800.0 55148.0 44617.0 89185.0 57773.0 67185.0 77263.0 57472.0 60526.0 83820.0 57660.0 True False 54361.57940709539 44513.692077760315 81852.55356405585 62021.8191450783 63233.31039079211 73958.64159884989 60447.61894734425 63338.25892102632 74379.30893626985 67626.45417287937 0.8038508017605976 0.6582289818710013 1.2103629351142537 0.917123630148145 0.9350380877451199 1.093634769165673 0.8938457543968926 0.9365899734903923 1.0998552244973183 1.0 16.04530009112026 -5.242151485815397 24.996492812814576 1.0012708422744172 0.7310398607848657 0.5551527176156409 0.09988257707033404 595.120873625839 771254.9479961926 0.024472511608536546 0.06453659650363304 5.725962694276608e-06 5.242151485815397 -0.2702309814895515 SKS(ph)MDLGIADETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SKSMDLGIADETK 13 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-8 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.186)KS(0.814)MDLGIADETK;S(0.017)KS(0.983)MDLGIADETK 103.88 0.0030424 6641700.0 58761.0 74268.0 66276.0 83358.0 94625.0 72365.0 80992.0 77387.0 64414.0 59006.0 True False 68708.07671734781 81640.83621988731 67856.27119312964 78687.72151028221 76083.91052124625 68570.05200869826 73319.8514286986 75355.67324830436 65355.93289068438 69703.3207087611 0.9857217133804618 1.1712617905394251 0.9735012694251839 1.1288948748806433 1.0915392516110523 0.9837415393048786 1.0518846259139982 1.081091581894072 0.9376301189976121 1.0 16.088939768153082 -8.257523503513665 24.924250920067447 0.9688150568003903 1.0601244441451974 0.2457315025905581 0.06276462401321554 403.3947041429279 2567622.013402826 0.04347030252443042 0.01502829812697909 5.52683496545227e-09 8.257523503513665 0.09130938734480709 SKS(ph)MDLGIADETK ddPTM_PC-9_Lapatinib_30min_R1 1 SKSMDLGIADETK 13 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-8 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.139)KS(0.861)MDLGIADETK 93.42399999999999 0.008961499999999999 4762100.0 28593.0 34341.0 30972.0 35216.0 34662.0 28358.0 29909.0 30652.0 30175.0 34124.0 True False 28185.25857668599 34261.48552440474 28425.601715377386 37805.9021171322 32623.249308113973 27145.19444572672 31457.54167413904 32076.203820627474 26776.373743163203 40022.287932628155 0.7042390635970606 0.8560601428403867 0.7102442959589881 0.9446212115802344 0.8151270452861312 0.6782519403044075 0.7860005836521228 0.8014585241759096 0.6690365575360767 1.0 15.288516022922726 -10.692838937460936 4.9116008900115125 1.0000185146809693 0.779025936473973 0.40307784988308204 0.08233363410574647 1.6383785465753466e-05 2.7687456585800296e-06 0.07824524815232792 0.01897567095798713 2.0284348458014318e-11 10.692838937460936 -0.22099257820699625 SKS(ph)MSDVSAEDVQNLR ddPTM_PC-9_AZD4547_30min_R2 1 SKSMSDVSAEDVQNLR 16 1 E9PMS6;E9PJ10 E9PMS6 LMO7 1 S(0.004)KS(0.949)MS(0.035)DVS(0.012)AEDVQNLR 95.073 0.005454100000000001 12697000.0 15367.0 19399.0 25808.0 37539.0 34801.0 21996.0 23793.0 29870.0 28582.0 34340.0 True False 20253.386346543586 25669.34738187904 25465.76905735236 28884.96352176855 29969.481858986383 20620.586642806833 25910.530906851527 25254.277844315748 30092.786168690523 33137.767052282514 0.6111874199184626 0.7746251381808463 0.7684817452296712 0.8716629420502541 0.9043905043964662 0.6222684410290251 0.7819033450857342 0.7620995646589966 0.9081114645175752 1.0 15.016188771151262 -14.522878745027784 0.14445597986775469 1.7907204054675867 0.7040467381059702 0.4090400352403648 0.09042370466160392 155.66669619771093 1.3541766636424915 35.162154171105435 0.5342554462241543 3.000000001744579e-15 14.522878745027784 -1.0866736673616164 SKS(ph)MSDVSAEDVQNLR ddPTM_PC-9_Lapatinib_30min_R1 2 SKSMSDVSAEDVQNLR 16 1 E9PMS6;E9PJ10 E9PMS6 LMO7 1 S(0.025)KS(0.913)MS(0.025)DVS(0.037)AEDVQNLR;S(0.002)KS(0.902)MS(0.087)DVS(0.009)AEDVQNLR 133.9 6.6675e-05 4089300.0 43521.0 25950.0 34610.0 30003.0 31418.0 33435.0 27443.0 31849.0 34797.0 23991.5 True False 42900.38255922608 25889.91436936324 31764.49939846349 32209.52070707399 29570.055010164593 32005.062990791772 28863.864260369744 33328.82081049081 30877.795431345487 28138.3988083357 1.5246206030215657 0.9200919549727055 1.1288666286531412 1.144682074003879 1.050879092715282 1.1374159279209097 1.0257820445639263 1.1844604605084177 1.0973543889852848 1.0 14.780252615124693 -4.747655724183865 24.99993016808041 1.0856463813190413 1.5246216932288525 0.7578903957362767 0.07580945438632382 332.4921121236573 603018.6961884465 0.01792778622772195 0.3562506965532248 1.787904328548638e-05 4.747655724183865 0.4389753119098112 SKS(ph)NPDFLK ddPTM_PC-9_AZD4547_30min_R2 1 SKSNPDFLK 9 1 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;H0Y2S9;K7EL39;J3QRL2;H7C3G6;J3QL44;Q6WCQ1;H0Y7E2 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 S(0.007)KS(0.993)NPDFLK 56.122 0.041549 30212000.0 254840.0 259580.0 261060.0 273580.0 273850.0 284590.0 257600.0 311530.0 308550.0 245890.0 True False 335873.81899870886 343484.1586364326 257598.17382642598 210510.3577688654 235830.6544950846 266794.5423111659 280525.9009626756 263390.1967472272 324859.3230826901 237281.46594309103 1.4155080240412201 1.4475810711604966 1.0856228184640753 0.8871757300224774 0.9938856941807904 1.12438003217307 1.1822495273607092 1.110032744025604 1.3690884865006843 1.0 17.856239890450112 -5.262514633702692 24.714327384571007 1.0912510207191546 1.4315445792246166 0.5535585871568489 0.12121228147081628 58.82160436424509 1352041.1456817538 0.03357870607774954 0.07680249629394317 5.463681395083586e-06 5.262514633702692 0.34029355850546206 SKS(ph)NPDFLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKSNPDFLK 9 1 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;H0Y2S9;K7EL39;J3QRL2;H7C3G6;J3QL44;Q6WCQ1;H0Y7E2 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 S(0.097)KS(0.903)NPDFLK 64.297 0.025577000000000003 4175400.0 37833.0 49099.0 40644.0 51467.0 44953.0 29880.0 40146.0 36508.0 34764.0 35006.0 True False 44237.379664189175 53973.22423601336 41613.10710322836 48583.47084826529 36144.782347810564 28313.040199266237 36343.08024812995 35549.70368342345 35272.35773297347 41352.31069265646 1.0697680231940476 1.3052045540371262 1.0063066949876205 1.1748671364304917 0.8740692295637382 0.6846785518153452 0.878864557732778 0.8596787721885767 0.8529718688546539 1.0 15.335680326399356 -6.299329930932805 5.930701386682139 0.8420820367655731 1.1416986694299147 0.6445633866590008 0.10175106678670527 0.11584170568161192 11.754837964372786 0.03058857608237908 0.03537639441021086 5.019611077703293e-07 6.299329930932805 0.2996166326643416 SKS(ph)NT(ph)KQNSVPPSQT(ph)KSETSWESPK ddPTM_PC-9_Lapatinib_30min_R1 1 SKSNTKQNSVPPSQTKSETSWESPK 25 3 Q86UE4;E5RJU9 Q86UE4 MTDH Protein LYRIC 3 S(0.613)KS(0.645)NT(0.675)KQNS(0.047)VPPS(0.036)QT(0.611)KS(0.104)ET(0.096)S(0.092)WES(0.082)PK 41.208999999999996 0.043907 4503700.0 7842.1 6688.3 5921.5 5745.0 6364.3 6366.6 6503.7 7677.9 5206.4 6322.7 True False 7730.270215934987 6672.813652277924 5434.657127651012 6167.506464758186 5989.964386695225 6094.315359269474 6840.429763151496 8034.643263551988 4620.000406177464 7415.570270531825 1.0424377268264484 0.8998382334524581 0.7328710981604997 0.8316968540190056 0.8077550570181085 0.8218269312998373 0.9224414999253886 1.0834828570744248 0.6230135023514691 1.0 12.856341927420598 -7.272710206443442 23.274291085914925 0.9141913781797493 0.8491563166144471 0.03172374080998963 0.13307507362001433 1056.7824175695694 2182241.4443406635 0.054519891384716426 0.03719134996910362 5.33690894930575e-08 7.272710206443442 -0.06503506156530214 SKS(ph)PASTSSVNGTPGSQLSTPR ddPTM_PC-9_AZD4547_30min_R2 1 SKSPASTSSVNGTPGSQLSTPR 22 1 Q5VZY9;O15075-2;O15075 Q5VZY9 DCLK1 Serine/threonine-protein kinase DCLK1 1 S(0.075)KS(0.912)PAS(0.007)T(0.007)SSVNGTPGSQLSTPR 85.925 0.00010652 4890800.0 9948.1 13543.0 13649.0 15565.0 19492.0 12344.0 10323.0 17017.0 13756.0 14777.0 True False 13111.3888666656 17920.50990220052 13468.005341901833 11976.729726852802 16785.87225641111 11572.12772862372 11241.727001699168 14387.413661758326 14483.114076569405 14259.661727768747 0.9194740462274051 1.2567275608861583 0.9444828074480006 0.8399027940143736 1.177157816003651 0.8115289092790033 0.788358603192349 1.008958973671921 1.015670241908019 1.0 13.799652137666525 -6.777394227079452 24.999573511023634 0.9169292812292295 1.0252416209129038 0.12529321426632167 0.13471571449296166 534.8605106110684 838064.9344787494 0.0486020937991788 0.04299636207427763 1.669574384459375e-07 6.777394227079452 0.10831233968367437 SKS(ph)PCQTLGGR ddPTM_PC-9_Lapatinib_30min_R1 1 SKSPCQTLGGR 11 1 B4DFJ1;Q9BSI4-2;Q9BSI4 B4DFJ1 TINF2 TERF1-interacting nuclear factor 2 1 S(0.269)KS(0.727)PCQT(0.003)LGGR 55.105 0.040694 5256800.0 12213.0 6431.3 14889.0 8537.4 9913.2 10536.0 10459.0 10200.0 9936.9 6675.5 True False 12038.840380410102 6416.408719987894 13664.883893202052 9165.268875931515 9330.125066101074 10085.399840615584 11000.515843719964 10673.929236930713 8817.701681804088 7829.351280455372 1.5376549025796038 0.8195326138968058 1.7453405018770944 1.1706294107419897 1.1916855856745279 1.2881526807708896 1.4050354173251696 1.363322305332798 1.1262365636621725 1.0 12.93467705919728 -8.473743312609738 3.8442863786531207 1.0015979715717318 1.3053785226840338 0.16993224395573603 0.22996124980124355 0.3436368124963836 10.939340250757525 0.20644124325630098 0.05427294556988295 3.3593610878667702e-09 8.473743312609738 0.30378055111230196 SKS(ph)PEILSSTK ddPTM_PC-9_AZD4547_30min_R2 1 SKSPEILSSTK 11 1 Q4KMZ1;Q4KMZ1-3 Q4KMZ1 IQCC IQ domain-containing protein C 1 S(0.023)KS(0.973)PEILS(0.004)STK 62.69 0.025481 10095000.0 34783.0 32598.0 47803.0 65046.0 53803.0 51165.0 48608.0 42461.0 43277.0 48655.0 True False 45843.27046865527 43134.66601136621 47169.10098607466 50050.64965068211 46333.38215738181 47965.644461684446 52934.017833826714 35899.62810671213 45564.533868253435 46951.60325942942 0.9763941438879072 0.918704858128638 1.0046323812510398 1.0660051239172605 0.9868328010306346 1.0215975841474885 1.1274166196485702 0.7646092063853497 0.9704574648172974 1.0 15.51888680207038 -7.755025485276225 24.999971035261215 0.900650003138921 1.0116354920310144 0.2654910708903694 0.0776231325525774 184.87067768451183 720594.0742764372 0.03697564078074639 0.020681736266846044 1.7578204584817854e-08 7.755025485276225 0.11098548889209348 SKS(ph)PEILSSTK ddPTM_PC-9_Lapatinib_30min_R1 1 SKSPEILSSTK 11 1 Q4KMZ1;Q4KMZ1-3 Q4KMZ1 IQCC IQ domain-containing protein C 1 S(0.225)KS(0.774)PEILSSTK 65.038 0.021558 7572000.0 71022.0 43319.0 47358.0 45255.0 40349.0 36109.0 54610.0 37485.0 48105.0 32966.0 True False 70009.21325616032 43218.69751701143 43464.40804716657 48583.20366625445 37975.75114918616 34564.7022441902 57437.438591217855 39226.68994572036 42686.90833189284 38664.129175566144 1.810701928349721 1.1177982910403568 1.124153290762177 1.256544624234203 0.9821959516208371 0.8939733800091227 1.4855484868262734 1.0145499402715044 1.1040442198519473 1.0 15.238708099431795 -4.761436066803731 10.197942832105376 1.1152576777044472 1.8132692285849772 0.641716853512172 0.1572834074616002 0.04524857810915952 110.00525806402639 0.03851402689662791 0.2175538747670574 1.7320639919373245e-05 4.761436066803731 0.69801155088053 SKS(ph)PLPPEEEAK ddPTM_PC-9_Lapatinib_30min_R1 1 SKSPLPPEEEAK 12 1 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 S(0.24)KS(0.76)PLPPEEEAK 54.236999999999995 0.040431 6044300.0 90866.0 46702.0 49077.0 30417.0 39845.0 37463.0 38026.0 43973.0 34449.0 30869.0 True False 89570.23417721633 46593.86438836232 45042.07850269842 32653.967648137463 37501.39543828403 35860.7948205184 39994.80021735304 46016.14611132884 30568.99085594797 36204.66551964298 2.47399700816514 1.2869574603052925 1.2440959709532649 0.9019270632515837 1.0358166523576224 0.9905020335310649 1.104686361365601 1.2710004484466955 0.84433844139128 1.0 15.143888001950273 -4.366256920189903 1.547160596793294 1.0438712331896831 4.998424000128559 0.9189428211674281 0.1263828393438206 0.8637361206089976 0.8283662768219683 0.034710207277772805 7.128693634509895 4.302719946217658e-05 4.366256920189903 3.9545527669388765 up SKS(ph)PLPPEEEAKDEEEDQTLVNLDTYTSDLHFQVSK ddPTM_PC-9_AZD4547_30min_R2 2 SKSPLPPEEEAKDEEEDQTLVNLDTYTSDLHFQVSK 36 2 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 S(0.283)KS(0.7)PLPPEEEAKDEEEDQT(0.014)LVNLDT(0.001)Y(0.001)T(0.001)S(0.001)DLHFQVSK;S(0.292)KS(0.708)PLPPEEEAKDEEEDQTLVNLDTYTSDLHFQVSK 65.891 4.9938e-06 38079000.0 101699.0 90052.0 132521.0 180182.0 169139.0 156858.0 139044.0 147814.0 141646.0 159260.0 True False 134037.16652938997 119159.54793716039 130763.68495231676 138643.82368414974 145656.9694016581 147049.64446342018 151418.64663608067 124972.74272781021 149133.11838395955 153684.3558749711 0.8721588203709884 0.7753524895800185 0.850858789158076 0.9021336159741757 0.947767055224257 0.9568289734255804 0.9852573853337832 0.8131780363479609 0.9703858114568655 1.0 17.229610789431092 -5.807767447204511 2.4947459263047596 0.9382143273844837 0.8219624176240757 0.473940457446276 0.05302995553897713 0.2502003826339992 3.173281055417892 0.015650685241486877 0.027558878927296134 1.5567990316792332e-06 5.807767447204511 -0.116251909760408 SKS(ph)PLPPEEEAKDEEEDQTLVNLDTYTSDLHFQVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKSPLPPEEEAKDEEEDQTLVNLDTYTSDLHFQVSK 36 2 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 S(0.276)KS(0.714)PLPPEEEAKDEEEDQT(0.01)LVNLDTYTSDLHFQVSK 64.14399999999999 6.065900000000001e-06 8876400.0 26242.0 26044.0 23477.0 37978.0 38338.0 29001.0 37111.0 28642.0 31702.0 25104.0 True False 30684.252296874467 28629.476201200247 24036.78071701832 35850.21578633725 30825.94411163575 27480.136506657313 33595.57741962713 27890.177848707528 32165.581775708346 29655.156476845354 1.0347020869990224 0.965413088396753 0.8105430411667581 1.2089032750283741 1.0394800693668416 0.9266562639153063 1.1328747311064922 0.940483246833787 1.0846539218507623 1.0 14.855995363806896 -5.748669791482171 24.999996686890956 1.0432770607602098 0.9397388640092853 0.2220767419080607 0.09465460803875421 376.5778713081869 737248.5351372021 0.02533405980306855 0.04350653580515956 1.7837344845521421e-06 5.748669791482171 -0.10353819675092446 SKS(ph)PPKVPIVIQDDSLPAGPPPQIR ddPTM_PC-9_Lapatinib_30min_R1 2 SKSPPKVPIVIQDDSLPAGPPPQIR 25 2 Q7Z422-4;Q7Z422-5;Q7Z422;Q7Z422-2;Q7Z422-3 Q7Z422-4 SZRD1 SUZ domain-containing protein 1 1 S(0.186)KS(0.814)PPKVPIVIQDDSLPAGPPPQIR;S(0.184)KS(0.816)PPKVPIVIQDDSLPAGPPPQIR 88.684 2.9777e-06 115048000.0 115369.0 125461.0 124429.0 121599.0 135000.0 126856.0 125944.0 140481.0 122940.0 116242.0 True False 113723.81690391657 125170.50276280082 114198.9279298298 130541.79610237242 127059.56542021186 121430.66459577944 132464.76407127528 147008.26011110423 109093.20258440703 136334.27481727127 0.8341542657291463 0.9181147068891279 0.8376391636137761 0.9575126744711665 0.9319708165133801 0.8906833205262057 0.9716174765943318 1.078292749993641 0.8001891140773263 1.0 17.056788779739783 -1.522878745359337 0.2308630464334601 0.9789580574432066 0.22254250658702382 0.19877010427176567 0.07216711625506889 79.50953433197463 1.0426650379157378 0.10132921469688888 22.75336330904012 0.029999999994542906 1.522878745359337 -0.7564155508561828 SKS(ph)PRDPDANWDSPSR ddPTM_PC-9_AZD4547_30min_R2 1 SKSPRDPDANWDSPSR 16 2 Q9UHB7;Q9UHB7-2;Q9UHB7-3 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 S(0.469)KS(0.531)PRDPDANWDSPSR 52.42 0.026099 6841100.0 16648.0 12113.0 20513.0 32058.0 26308.0 26146.0 22475.0 28877.0 15638.0 26063.0 True False 21941.717700088353 16028.290367374648 20240.98421704391 24667.52339116269 22655.588309135204 24511.08648676247 24475.23146015585 24414.723177445798 16464.592754390247 25150.5423029598 0.8724152917174346 0.6372940262798383 0.8047931521008151 0.9807948907829209 0.9007991969409351 0.9745748696590898 0.9731492532181115 0.9707434091619007 0.6546416596533046 1.0 14.61830188770573 -5.591575159171427 5.577194869586035 0.923519758391795 0.7467330097013521 0.2947706468212048 0.1082498422777596 0.2171250877474859 12.393666885568864 0.028678513594917365 0.050802755813033354 2.5610900025047e-06 5.591575159171427 -0.17678674869044286 SKS(ph)PVGNPQLIQFSR ddPTM_PC-9_Lapatinib_30min_R1 1 SKSPVGNPQLIQFSR 15 1 G8JLP4;Q9Y4F3-3;Q9Y4F3-4;Q9Y4F3-5;Q9Y4F3 G8JLP4 KIAA0430 Meiosis arrest female protein 1 1 S(0.008)KS(0.992)PVGNPQLIQFSR 139.12 0.00028042 6876000.0 10632.0 9466.6 10153.0 7232.8 6966.5 9461.7 9013.9 8896.0 8203.2 5419.4 True False 10480.385730329986 9444.68066932617 9318.25953171338 7764.724239913498 6556.7441666659715 9057.045147299974 9480.595636648564 9309.340636444664 7279.269232474446 6356.136069103416 1.6488611345616346 1.4859154314263159 1.4660258103989576 1.2216107640705016 1.0315613283575997 1.4249293987467362 1.4915658717145555 1.4646226158839644 1.1452349593109394 1.0 12.633934294200547 -1.5228787937026234 0.033432258704201315 7.14339195469445e-09 3.380395805448022 0.4039574565450682 0.16211512686406404 1441.7634523044867 3.701849221837265 113.40359390327635 303.4092301199409 0.029999996655107185 1.5228787937026234 3.38039579830463 SKS(ph)QSSGSSATHPISVPGAR ddPTM_PC-9_AZD4547_30min_R2 3 SKSQSSGSSATHPISVPGAR 20 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 S(0.143)KS(0.683)QS(0.08)S(0.063)GS(0.009)S(0.003)AT(0.018)HPISVPGAR;S(0.064)KS(0.453)QS(0.169)S(0.169)GS(0.018)S(0.121)AT(0.005)HPISVPGAR;S(0.155)KS(0.436)QS(0.155)S(0.155)GS(0.022)S(0.028)AT(0.049)HPISVPGAR 65.53399999999999 0.0026941999999999995 53158000.0 50041.0 54154.0 184225.0 324615.0 233343.0 192493.0 95143.0 252770.0 136001.0 187550.0 True False 65952.99708253982 71658.22146081123 181782.05612952338 249780.02700175502 200947.35224336822 180456.38228013387 103610.54268358651 213710.20457675605 143189.7352084555 180983.9315857767 0.36441355044429247 0.39593692563170485 1.004409919359987 1.3801226706326282 1.1103049341600246 0.997085104180131 0.5724847602533192 1.1808241908783423 0.7911737464968884 1.0 17.465502089697956 -5.258922882230652 6.840121009717067 1.0131903656739152 0.37638086180287394 0.5996077738644292 0.2040456565768157 0.08787726264514148 26.8503082876344 0.05554014288727964 0.13277688416784644 5.509055121369184e-06 5.258922882230652 -0.6368095038710413 SKS(ph)QSSSNCSNPISVPLR ddPTM_PC-9_AZD4547_30min_R2 1 SKSQSSSNCSNPISVPLR 18 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 S(0.018)KS(0.981)QS(0.001)SSNCSNPISVPLR 97.083 0.0038354 4368900.0 4853.6 5337.3 6481.0 9341.0 6112.9 8029.1 6457.4 8534.2 7811.6 8413.2 True False 6396.94383884844 7062.4778484098715 6395.057705389829 7187.576767011375 5264.229351334672 7527.039107735961 7032.096090358635 7215.435486406412 8224.505228302527 8118.65642877878 0.7879313399902892 0.8699072205315899 0.7876990191038029 0.8853160409070964 0.6484113963332878 0.9271286663953815 0.8661650055089735 0.8887474854619224 1.0130377237234154 1.0 12.98702527759954 -7.900793719337752 1.0765183335890272 1.0115147808654572 0.8118475282804626 0.514020523103971 0.07101368205500362 0.41386204526604986 0.8697907825892262 0.0618352234342916 0.023091396327753755 1.2566266929776461e-08 7.900793719337752 -0.19966725258499463 SKS(ph)QSSSNCSNPISVPLRR ddPTM_PC-9_AZD4547_30min_R2 1 SKSQSSSNCSNPISVPLRR 19 2 P35568 P35568 IRS1 Insulin receptor substrate 1 1 S(0.133)KS(0.843)QS(0.011)S(0.011)S(0.003)NCSNPISVPLRR 70.501 0.019625 25491000.0 18698.0 8839.0 22623.0 34654.0 26023.0 28318.0 20649.0 20005.0 16238.0 24267.0 True False 24643.575057439444 11696.03389393417 22323.004238394406 26665.05569896285 22410.155639677112 26547.270983406244 22486.72099758656 16913.686919167598 17096.307529465976 23417.419716299937 1.05236082181531 0.49945869509239843 0.9532648989015748 1.1386846211925885 0.9569865472444982 1.1336548306783665 0.9602561370984202 0.722269452573148 0.7300679467074639 1.0 14.515294498617497 -10.797596636573632 4.009799249873152 1.000114081022039 0.9060466775450761 0.021644361955697744 0.19108981629031077 290616354.8377983 60.52031901454137 311405.2636957321 0.048636084652577224 1.5936882234196117e-11 10.797596636573632 -0.09406740347696296 SKS(ph)QSSSNCSNPISVPLRR ddPTM_PC-9_Lapatinib_30min_R1 1 SKSQSSSNCSNPISVPLRR 19 2 P35568 P35568 IRS1 Insulin receptor substrate 1 1 S(0.13)KS(0.44)QS(0.181)S(0.181)S(0.065)NCS(0.002)NPIS(0.001)VPLRR 71.428 0.017769999999999998 22138000.0 20532.0 15061.0 17580.0 17519.0 24329.0 30853.0 20680.0 18622.0 32153.0 22358.0 True False 20239.20991489234 15026.127179845087 16134.640260762448 18807.405701670803 22898.016052654333 29533.4891118558 21750.70921198288 19487.246102953308 28531.5905538998 26222.550509837638 0.7718246136011602 0.5730230998776376 0.6152963745730754 0.7172225941414443 0.8732184935276958 1.1262630269613183 0.8294658143121089 0.7431483865630265 1.0880555094439004 1.0 14.67852039420683 -6.239955697407191 3.0520415374626055 0.9382825816922863 0.6491795451505227 0.5773592785315387 0.11643525422396007 0.19887455396682477 3.770751751394802 0.03778103263464521 0.04789049812150971 5.754986412411617e-07 6.239955697407191 -0.2891030365417636 SKS(ph)SEVTDAYTK ddPTM_PC-9_Lapatinib_30min_R1 1 SKSSEVTDAYTK 12 1 Q6UB98-2;Q6UB98 Q6UB98-2 ANKRD12 Ankyrin repeat domain-containing protein 12 1 S(0.151)KS(0.607)S(0.241)EVT(0.001)DAYTK 87.38799999999999 0.0040604 4900300.0 40588.0 34347.0 33368.0 27102.0 28031.0 33737.0 43929.0 31787.0 30687.0 29983.0 True False 40009.20767707238 34267.471631773406 30624.611844204843 29095.171489621654 26382.271691066384 32294.14715478817 46203.42867375218 33263.940064148686 27230.7069115642 35165.5216001638 1.1377396340649195 0.9744622025345926 0.8708703994898855 0.8273777884041433 0.7502312063229427 0.918346883119679 1.3138843552241515 0.9459248306441655 0.774358111936476 1.0 15.101873996098515 -9.2601563192495 15.942811858881655 0.9999990913630932 0.9453142323812461 0.009968793463029924 0.1616115580130403 0.0 0.0 0.16702119663573897 0.04050859032036523 5.49343108603023e-10 9.2601563192495 -0.05468485898184705 SKS(ph)TAALSGEAASCSPIIMPYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKSTAALSGEAASCSPIIMPYK 22 1 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 S(0.196)KS(0.604)T(0.196)AALS(0.005)GEAASCSPIIMPYK 95.646 7.6077e-05 3988700.0 34980.0 32081.0 25647.0 38403.0 37900.0 43939.0 43159.0 38627.0 40427.0 33423.0 True False 40901.42311350769 35265.78966405716 26258.52174678915 36251.40441420584 30473.767067426434 41634.761489811215 39070.66707589898 37613.08217868955 41018.16839463002 39482.32532367759 1.0359426092104829 0.8932044750390685 0.6650702949109708 0.9181679173406191 0.7718331384385632 1.0545164487777219 0.9895736068125719 0.9526562042720655 1.0388995090426292 1.0 15.268919339813547 -6.768018100985291 24.99921820903816 1.0030729521413622 0.8516165523939607 0.39002804719803186 0.0937886859386193 171.8982052259431 653211.2306310382 0.03327695701941198 0.030024656181859757 1.70601128257658e-07 6.768018100985291 -0.15145639974740144 SKS(ph)VKEDSNLTLQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKSVKEDSNLTLQEK 15 2 P46940;H0YLE8 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 1 S(0.196)KS(0.8)VKEDS(0.003)NLTLQEK 50.023999999999994 0.032264 16988000.0 226780.0 148830.0 103770.0 176420.0 175740.0 134050.0 132770.0 141750.0 98487.0 106450.0 True False 265169.37489083066 163604.8588167963 106244.27034991627 166535.75936135685 141305.0085601458 127020.18201846186 120193.06442844175 138029.21269653947 99927.1860559017 125748.54234226391 2.108727226189942 1.3010477558578342 0.8448946474523683 1.3243553862284765 1.1237109069267786 1.010112559974944 0.9558207370809818 1.0976605384486278 0.7946588023574751 1.0 16.94018215106582 -4.79334123954232 3.0089704080469364 1.0345495392228312 2.268395797838374 0.842201698007947 0.14181811785296647 0.13327013324279005 1.7854892854408684 0.03592104122778687 0.39577140658469384 1.609380594674432e-05 4.79334123954232 1.2338462586155428 up SKS(ph)YNTPLLNPVQEHEAEGAAAGGTSIR ddPTM_PC-9_AZD4547_30min_R2 3 SKSYNTPLLNPVQEHEAEGAAAGGTSIR 28 1 P85299;P85299-5;P85299-2;P85299-4;P85299-3 P85299 PRR5 Proline-rich protein 5 1 S(0.095)KS(0.421)Y(0.349)NT(0.136)PLLNPVQEHEAEGAAAGGTSIR;S(0.146)KS(0.356)Y(0.189)NT(0.309)PLLNPVQEHEAEGAAAGGTSIR;S(0.197)KS(0.487)Y(0.031)NT(0.285)PLLNPVQEHEAEGAAAGGTSIR 97.734 1.7813000000000002e-08 30358000.0 25614.8 25475.2 33632.5 47838.0 43124.1 35284.9 32367.5 38121.1 31370.6 35751.0 True False 33759.77357906193 33709.560205311886 33186.5110749149 36809.68818973238 37137.0630911501 33078.529625057956 35248.144795844026 32230.359930731334 33028.78587165078 34499.36837175749 0.978562077290058 0.9771065905342148 0.9619454686040761 1.0669670178618749 1.0764563191699454 0.9588155142033647 1.021704061825651 0.9342304352770803 0.9573736398805903 1.0 15.074282328243884 -9.716590109331417 8.29723483010095 0.9999999999986571 0.9940208465335919 0.0014925381820686257 0.04538097993568031 0.0 0.0 0.04710504261105533 0.011424650952035405 1.9204804506707486e-10 9.716590109331417 -0.005979153465065168 SKS(ph)YNTPLLNPVQEHEAEGAAAGGTSIR ddPTM_PC-9_Lapatinib_30min_R1 1 SKSYNTPLLNPVQEHEAEGAAAGGTSIR 28 1 P85299;P85299-5;P85299-2;P85299-4;P85299-3 P85299 PRR5 Proline-rich protein 5 1 S(0.09)KS(0.426)Y(0.359)NT(0.125)PLLNPVQEHEAEGAAAGGTSIR 87.792 1.3686e-07 30255000.0 38635.0 32341.0 33628.0 33161.0 35695.0 35363.0 33860.0 29861.0 39496.0 25348.0 True False 38084.05781520871 32266.116401525127 30863.23564783389 35599.770561853125 33595.49027907013 33850.606925179294 35613.105121747576 31248.451072939988 35047.54456868182 29729.368025913074 1.2810248028822349 1.0853280289510676 1.038139647668679 1.197461396785267 1.1300438761357867 1.1386251768175502 1.1979099283478225 1.0510970514308555 1.178886296477384 1.0 14.859601174931843 -13.803434298225968 0.37115916683741174 4.5293693974824576e-08 1.1428920600748984 0.2724567021844113 0.07033437849063716 419.86934199394983 5.525603664152639 330.4240846171361 0.047963803251077367 1.5724096547751346e-14 13.803434298225968 1.1428920147812045 SKSDS(ph)YTLDPDTLR ddPTM_PC-9_Lapatinib_30min_R1 1 SKSDSYTLDPDTLR 14 1 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 S(0.004)KS(0.041)DS(0.76)YT(0.068)LDPDT(0.127)LR 167.18 0.0019586 19104000.0 46337.0 43474.0 37641.0 36208.0 43832.0 54754.0 49974.0 57158.0 57225.0 45126.0 True False 45676.2258828349 43373.338624034586 34546.30227846183 38870.857106347175 41253.88793702764 52412.29905780807 52561.409195340064 59813.769345537825 50779.717894035304 52925.96897338461 0.8630210607160456 0.8195095803696321 0.6527287633757723 0.7344382702921233 0.7794640086376762 0.9902945581244842 0.9931118922314323 1.1301402790682387 0.959448053177286 1.0 15.691688157014244 -6.787557364039347 3.6135613951887295 1.0271663568147404 0.7611446852790019 0.7759055148915631 0.06587461222347629 0.10852120617476416 2.989119524334261 0.024983333509392868 0.022913553187379226 1.6309574690335712e-07 6.787557364039347 -0.2660216715357385 SKSDSYT(ph)LDPDTLR ddPTM_PC-9_AZD4547_30min_R2 1 SKSDSYTLDPDTLR 14 1 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 S(0.003)KS(0.03)DS(0.073)YT(0.893)LDPDTLR 105.19 0.010248 16650000.0 11026.0 15518.0 15216.0 18144.0 16862.0 17247.0 17645.0 14658.0 12166.0 14786.0 True False 14532.038644952796 20533.8900289705 15014.22589804222 13961.181122005593 14521.002359306594 16168.54236354289 19215.370817105664 12392.94290733111 12809.069922618739 14268.346640508136 1.0184809082010968 1.439121893119302 1.0522751007055378 0.978472241651987 1.0177074278586113 1.1331756068807621 1.3467132037956537 0.8685619448119717 0.8977262920045354 1.0 13.800530550261264 -6.220215929839308 0.2697131274955335 0.947558555573022 1.2643091196652212 0.11959832891888356 0.16407468633114441 9.05567532761638 1.0659378115050997 0.26511419165963906 0.9360767738042689 6.022600698242385e-07 6.220215929839308 0.31675056409219915 SKSEEAHAEDSVMDHHFR ddPTM_PC-9_AZD4547_30min_R2 1 SKSEEAHAEDSVMDHHFR 18 1 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 42.58 0.032455 4239800.0 10761.0 8191.1 25936.0 51959.0 35462.0 26031.0 15532.0 30808.0 20273.0 25816.0 False True 14182.774157295216 10838.712889309212 25592.07169371863 39980.65530854766 30538.713418676914 24403.277454942025 16914.317910529047 26047.33149741142 21344.589391850215 24912.18969777885 0.5693106197950853 0.4350766841774484 1.027291137559072 1.6048631530817343 1.2258542420058611 0.9795717578819577 0.6789574949341813 1.0455657175625062 0.8567929857146713 1.0 14.604564214748708 -5.278748704478526 9.604021890624772 1.0641995059196454 0.5020370649367166 0.4760292429830474 0.23062082771832706 0.28639919862154317 154.97981108508387 0.06721181229822314 0.14569714896473715 5.263217234801554e-06 5.278748704478526 -0.5621624409829288 SKSEEAHAEDSVMDHHFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKSEEAHAEDSVMDHHFR 18 1 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 42.095 0.025802 7179100.0 27715.0 20548.0 65441.0 91759.0 96638.0 110060.0 85534.0 94427.0 98190.0 58346.0 False True 32406.60210379833 22587.869642998885 67001.36162637464 86618.04071669179 77702.47762168752 104288.25985044328 77431.60030746629 91948.39130367653 99625.84299277028 68923.66793331804 0.47018104339935773 0.32772297703093944 0.9721096342579565 1.2567241894394336 1.1273700305222114 1.5130979383067602 1.12343992461892 1.3340612022075544 1.4454518452087584 1.0 16.07271185952787 -5.433257417621998 2.6746535626693486 1.2710763297715395 0.38617673518855106 0.832838065439622 0.1514194896844532 0.0968835260797684 1.3332493426191978 0.04043637201931451 0.1003040335235201 3.687589607643319e-06 5.433257417621998 -0.8848995945829885 down SKSISS(ph)SNPDLAVAPGSVDDEVSR ddPTM_PC-9_AZD4547_30min_R2 1 SKSISSSNPDLAVAPGSVDDEVSR 24 1 Q96HP0;K7ESB7;K7EKT0;K7EP20 Q96HP0 DOCK6 Dedicator of cytokinesis protein 6 1 S(0.123)KS(0.123)IS(0.123)S(0.314)S(0.314)NPDLAVAPGS(0.002)VDDEVSR 68.406 0.00045486 8558300.0 41195.0 43801.0 51953.0 73155.0 53658.0 49395.0 48714.0 60256.0 47990.0 50666.0 True False 54294.15309077002 57958.816674760776 51264.069274512825 56290.244983483215 46208.512904499636 46306.32284149131 53049.451628477465 50944.81974513191 50526.6534264732 48892.198761530184 1.1104870401838065 1.1854409935100827 1.0485122488467198 1.1513134285090494 0.9451101418015556 0.9471106641644124 1.0850289611073562 1.041982586907439 1.0334297639775827 1.0 15.577316666691909 -6.249040766724863 24.998779833309978 1.0116054271449793 1.122943888032737 0.5508350380428262 0.05090377105542191 656.5996784654363 1323873.973587631 0.01581551904279161 0.02026398772091791 5.63584750288847e-07 6.249040766724863 0.11133846088775767 SKSPLPPEEEAKDEEEDQT(ph)LVNLDTYTSDLHFQVSK ddPTM_PC-9_AZD4547_30min_R2 1 SKSPLPPEEEAKDEEEDQTLVNLDTYTSDLHFQVSK 36 2 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 S(0.024)KS(0.062)PLPPEEEAKDEEEDQT(0.716)LVNLDT(0.074)Y(0.082)T(0.031)S(0.011)DLHFQVSK 57.025 0.00019573 8079200.0 4651.4 4568.3 5149.2 6791.0 7638.8 7428.3 6678.9 7603.1 5357.9 6192.2 True False 6130.4484448697085 6044.913637024485 5080.918243572489 5225.439869904102 6578.284475285918 6963.807226712217 7273.30916125628 6428.215596856948 5641.107655630355 5975.412962758989 1.0259455677920435 1.0116311081256895 0.8503041170942784 0.8744901653611223 1.100892024749461 1.1654102017907835 1.2172061088641515 1.0757776302525022 0.9440531877525202 1.0 12.54482270633066 -6.276204126996382 24.298232746303672 1.0984205861302425 0.9392177243063047 0.3825274396609304 0.08803012789087038 571.7106921302337 940857.7364710163 0.02946530413638905 0.033564334397028 5.294145500939294e-07 6.276204126996382 -0.15920286182393784 SKSQS(ph)SGSSATHPISVPGAR ddPTM_PC-9_Lapatinib_30min_R1 1 SKSQSSGSSATHPISVPGAR 20 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 S(0.084)KS(0.23)QS(0.305)S(0.305)GS(0.014)S(0.046)AT(0.016)HPISVPGAR 44.254 0.038102 11391000.0 18878.0 10376.0 29663.0 14838.0 35192.0 40311.0 17214.0 19319.0 55893.0 21153.0 True False 18608.7962581988 10351.97500949954 27224.222642491284 15929.236018116966 33122.07575013407 38586.992499530636 18105.25669125111 20216.631267476914 49597.74176061712 24809.267865399208 0.7500743818463086 0.417262414419619 1.0973408320710725 0.642067960430748 1.3350686497415147 1.5553458775519464 0.7297779519121564 0.814882219707599 1.9991618466818888 1.0 14.598591540715187 -6.259594134823899 24.990489534085107 1.2201357906627304 0.7310599865873485 0.3055990116445868 0.3776916405587518 227.92724820080795 3086856.8018077677 0.11462065531903975 0.1405206302636116 5.500546813428302e-07 6.259594134823899 -0.48907580407538187 SKSQSS(ph)GSSATHPISVPGAR ddPTM_PC-9_AZD4547_30min_R2 1 SKSQSSGSSATHPISVPGAR 20 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 S(0.09)KS(0.219)QS(0.155)S(0.486)GS(0.042)S(0.005)AT(0.002)HPISVPGAR 61.437 0.0049759999999999995 14695000.0 19044.0 21767.0 90062.0 186130.0 138180.0 106190.0 50464.0 134480.0 76417.0 108550.0 True False 25099.59586019237 28802.757073115165 88867.71903453468 143220.6041798338 118996.092160419 99549.92251316864 54955.19823827828 113699.20604297209 80456.24661160249 104749.6975400486 0.23961497216348646 0.27496744858955896 0.8483816289833026 1.3672650856588562 1.1360041599635513 0.9503599996086677 0.5246334789393301 1.0854370820450518 0.7680809443945356 1.0 16.676586552651635 -5.296111661147791 4.179925578069086 0.9745246327620363 0.2439844735083124 0.6443692497247141 0.21032193919369493 0.12887126740282218 5.162496894938342 0.059701229391750356 0.14366581537798423 5.0569462649857565e-06 5.296111661147791 -0.7305401592537238 SKSQSSSNCS(ph)NPISVPLRR ddPTM_PC-9_Lapatinib_30min_R1 1 SKSQSSSNCSNPISVPLRR 19 2 P35568 P35568 IRS1 Insulin receptor substrate 1 1 S(0.187)KS(0.187)QS(0.064)S(0.187)S(0.064)NCS(0.31)NPISVPLRR 63.54600000000001 0.035865 18378000.0 34462.0 24335.0 24887.0 26199.0 36042.0 41905.0 33799.0 32891.0 48690.0 28415.0 True False 33970.56556044322 24278.653802637942 22840.88692659812 28125.76185730195 33922.08042129838 40112.82083532611 35548.94684022287 34419.235934498836 43206.01947156973 33326.494889392474 1.0193260849419765 0.7285090701322334 0.6853672131559256 0.8439459940401391 1.0178712322997843 1.2036315540670213 1.066687239633406 1.0327889581167498 1.2964465544596417 1.0 15.024381969676686 -6.340522703711772 2.978544170506231 1.1180470315925015 0.7987480202958988 0.6035289623566027 0.11464368980416703 0.17531462387687968 3.0382756463499088 0.03720796393477356 0.0440316353083524 4.565383830171172e-07 6.340522703711772 -0.31929901129660276 SKST(ph)AALSGEAASCSPIIMPYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKSTAALSGEAASCSPIIMPYK 22 1 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 S(0.097)KS(0.377)T(0.523)AALS(0.003)GEAASCSPIIMPYK 73.21300000000001 0.00075653 16468000.0 56687.0 51403.0 43829.0 67513.0 67737.0 74980.0 69882.0 72281.0 57808.0 52262.0 True False 66282.98948071488 56505.950129407815 44874.04958240809 63730.465490099275 54464.421104123154 71047.91680525377 63262.27105813322 70383.70033805017 58653.33263800856 61736.68689423565 1.0736402099819147 0.9152734455318459 0.7268619655486886 1.0322948751571213 0.8822051173142641 1.1508216650331378 1.0247111440643248 1.140062803477423 0.9500563698614188 1.0 15.913840442199472 -6.747685178834021 24.998411055865922 1.060108128780465 0.9202920485711634 0.272749045147077 0.10322322729596349 295.18101364051597 536493.6852062101 0.033690503926269155 0.033520924442264156 1.7877830737021575e-07 6.747685178834021 -0.13981608020930159 SKSVIEQVS(ph)WDT ddPTM_PC-9_Lapatinib_30min_R1 1 SKSVIEQVSWDT 12 1 Q6WCQ1;H0Y7E2 Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 S(0.015)KS(0.015)VIEQVS(0.97)WDT 103.43 0.010125 19605000.0 201640.0 169110.0 172140.0 138420.0 194390.0 166470.0 189240.0 156550.0 192430.0 166310.0 True False 198764.5766237532 168718.43618508746 157987.3136796156 148599.86855558367 182956.36238544458 159350.46616052365 199037.92124156855 163823.88451387314 170756.50702226665 195056.46190585423 1.0190104684647092 0.8649722984646412 0.8099568306322997 0.7618300214391602 0.9379661693738202 0.8169453326669874 1.0204118299738052 0.8398792991177304 0.8754209184040457 1.0 17.573532267749854 SKSYNT(ph)PLLNPVQEHEAEGAAAGGTSIR ddPTM_PC-9_AZD4547_30min_R2 1 SKSYNTPLLNPVQEHEAEGAAAGGTSIR 28 1 P85299;P85299-5;P85299-2;P85299-4;P85299-3 P85299 PRR5 Proline-rich protein 5 1 S(0.246)KS(0.246)Y(0.232)NT(0.276)PLLNPVQEHEAEGAAAGGTSIR 44.301 0.021919 31655000.0 26326.0 24322.0 35438.0 51265.0 35390.0 32792.0 27720.0 33559.0 23644.0 29081.0 True False 34697.12038518298 32183.61085736697 34968.068965222126 39446.646286354575 30476.709375866456 30741.511056143012 30187.026299244477 28373.227659102504 24893.77356981732 28062.883041567493 1.2364061217013476 1.1468390760028377 1.2460611731669369 1.4056519505827376 1.0860149091140614 1.0954509203707925 1.0756922677734375 1.0110589000095007 0.8870711370939328 1.0 14.776375611461976 -7.055203523488073 1.063294420375244 0.9626944421065619 1.2436208712228152 0.6792066555234726 0.07929295781042905 0.3245396961143919 0.7471074824283348 0.05344017305086676 0.036421482766635406 8.80636083673072e-08 7.055203523488073 0.2809264291162533 SKSYNT(ph)PLLNPVQEHEAEGAAAGGTSIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKSYNTPLLNPVQEHEAEGAAAGGTSIR 28 1 P85299;P85299-5;P85299-2;P85299-4;P85299-3 P85299 PRR5 Proline-rich protein 5 1 S(0.054)KS(0.235)Y(0.195)NT(0.516)PLLNPVQEHEAEGAAAGGTSIR 92.499 5.3310000000000006e-08 11097000.0 23017.0 16753.0 22277.0 25318.0 30115.0 25919.0 25450.0 22836.0 22951.0 18928.0 True False 26913.323493527936 18416.127123280126 22808.16816599297 23899.514542063476 24214.181932336334 24559.762012208234 23039.19175795615 22236.57919674202 23286.61495597383 22359.49656603445 1.2036641081808188 0.8236378251581674 1.0200662657423192 1.0688753421384458 1.0829484403114547 1.0984040691468937 1.0303985015903354 0.994502677243675 1.0414641889275689 1.0 14.448600085178587 -4.480003341853079 20.7091686136604 1.023628964241014 2.594410829317751 0.36768683848715056 0.07275787950742832 9.157407555947971 56822.05793639557 0.018037371252964705 8409.005449639091 3.3112857347116916e-05 4.480003341853079 1.570781865076737 SKSYNT(ph)PLLNPVQEHEAEGAAAGGTSIR ddPTM_PC-9_Lapatinib_30min_R1 1 SKSYNTPLLNPVQEHEAEGAAAGGTSIR 28 1 P85299;P85299-5;P85299-2;P85299-4;P85299-3 P85299 PRR5 Proline-rich protein 5 1 S(0.064)KS(0.284)Y(0.236)NT(0.416)PLLNPVQEHEAEGAAAGGTSIR 94.837 1.18e-09 11303000.0 8811.5 5939.5 9262.9 9422.0 10676.0 8672.6 7282.4 8904.9 8854.3 6159.2 True False 8685.8463941688 5925.747452671796 8501.34011782801 10114.925310870605 10048.05866982358 8301.693114818025 7659.44703894314 9318.654162935709 7857.035494087489 7223.809513381881 1.2023913944683262 0.8203078225823279 1.1768499850500687 1.4002203812452452 1.3909639576195727 1.1492126279685806 1.0603057880685052 1.2899916789988985 1.0876581780752352 1.0 12.818544135160453 -5.496770163134043 24.51702361327689 1.2154847007460337 1.0081568529348512 0.1800042970610034 0.15320953139568247 819.9854589525396 769997.9800549878 0.039989498841576473 0.08275196233554971 3.185883105349746e-06 5.496770163134043 -0.2073278478111824 SKT(ph)FSPGPQSQYVCR ddPTM_PC-9_AZD4547_30min_R2 1 SKTFSPGPQSQYVCR 15 1 H0YBE8;H3BLZ3;Q8IX03;Q8IX03-2;H0YAU4 H0YBE8 WWC1 Protein KIBRA 1 S(0.081)KT(0.915)FS(0.004)PGPQSQYVCR 70.615 0.016835 34393000.0 23615.0 17084.0 25044.0 29702.0 23072.0 20569.0 21782.0 21598.0 15190.0 18560.0 True False 31124.07877748597 22606.06890417144 24711.900196541108 22854.66279132554 19868.851051709258 19282.817178391244 23720.555802674724 18260.525372665925 15992.912389000385 17910.220049224332 1.7377831591094222 1.2621882278409235 1.3797653031968944 1.2760682296762371 1.1093582880110817 1.076637647409941 1.3244145374809078 1.0195589625632078 0.8929489612660017 1.0 14.1284954422767 -1.5228787452919768 0.30229299903013035 1.0006308312878207 6.5255469013482506 0.7311081758779421 0.12008751889786769 30.326946021137207 0.43245257950724664 0.12387436172920803 90.84157242349112 0.029999999999195993 1.5228787452919768 5.52491607006043 SKT(ph)FSPGPQSQYVCR ddPTM_PC-9_Lapatinib_30min_R1 2 SKTFSPGPQSQYVCR 15 1 H0YBE8;H3BLZ3;Q8IX03;Q8IX03-2;H0YAU4 H0YBE8 WWC1 Protein KIBRA 1 S(0.001)KT(0.986)FS(0.013)PGPQSQYVCR;S(0.28)KT(0.697)FS(0.023)PGPQSQYVCR 110.57 0.0052807999999999996 4568600.0 21622.0 20620.0 20976.0 19687.6 21035.8 25441.0 16513.5 14211.5 19760.5 15817.1 True False 21313.666315010814 20572.25565688903 19251.434249701553 21135.49177990832 19798.51560197404 24352.947735867612 17368.48822882394 14871.81817163146 17534.864402710078 18551.064660039054 1.148918765882084 1.1089528301415408 1.0377536061944288 1.139314220894092 1.0672441697980886 1.3127520270211999 0.9362529076963163 0.8016692542540117 0.9452214589323287 1.0 14.179214366162762 -7.490109693575635 21.2410563948949 0.8978594686324514 1.1269617967872954 0.6145044389104217 0.08302392624250435 62.92167406907437 40786.3504593759 0.033695138443716965 0.02267542134039243 3.235119343557738e-08 7.490109693575635 0.229102328154844 SKT(ph)PPPPPQTAQTK ddPTM_PC-9_AZD4547_30min_R2 1 SKTPPPPPQTAQTK 14 1 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 S(0.157)KT(0.843)PPPPPQTAQTK 79.514 0.0091432 13535000.0 18860.0 18468.0 25262.0 29012.0 33881.0 28702.0 19380.0 28449.0 27717.0 28112.0 True False 24857.087687630134 24437.419838576316 24927.009374102436 22323.73163093179 29177.207978630457 26907.259402702377 21104.782455965305 24052.860742984205 29182.064034623003 27127.807436626845 0.916295492943861 0.9008254683193424 0.9188729842002276 0.8229095433931461 1.0755461180116088 0.9918700383567788 0.7779759755840238 0.8866496416702304 1.0757251245901498 1.0 14.727484828270141 SKT(ph)SEDISQTSK ddPTM_PC-9_AZD4547_30min_R2 1 SKTSEDISQTSK 12 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 S(0.003)KT(0.899)S(0.074)EDIS(0.024)QTSK 108.06 0.0070191 0.0 4191.3 5360.8 5611.3 7255.4 7931.5 7986.9 4557.9 8260.0 5018.0 8597.4 True False 5524.046215544226 7093.573763842323 5536.890495641709 5582.779624812582 6830.348132655686 7487.4778804070675 4963.544270177723 6983.606795917244 5283.241235549961 8296.407642844897 0.6658359199970544 0.8550175050716151 0.6673840936946862 0.672915298421644 0.82328984142268 0.90249638189663 0.5982763243870317 0.841762735940313 0.6368107092840848 1.0 13.018271067176574 -10.66083162181385 3.879575258600126 1.000103664200944 0.745662018186239 0.36922270788766676 0.1015775281707326 102516222.3694948 197950998.66669008 150496.4220702857 0.025133337176010063 2.1835763314348265e-11 10.66083162181385 -0.254441646014705 SKT(ph)SEDISQTSK ddPTM_PC-9_Lapatinib_30min_R1 1 SKTSEDISQTSK 12 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 S(0.002)KT(0.499)S(0.499)EDISQTSK 189.09 0.0024009 4361500.0 16432.0 10031.0 13749.0 14776.0 14537.0 11371.0 10022.0 10133.0 13202.0 10313.0 True False 16197.676666740253 10007.773835802805 12618.610292674792 15862.676331291046 13681.96224084163 10884.68883709565 10540.89012197738 10603.81617233518 11715.051736776832 12095.588308791284 1.3391392178061732 0.8273904154400643 1.0432407230248872 1.3114431416090588 1.131153102399934 0.899889162826786 0.8714656826006617 0.8766680794375369 0.9685392258483309 1.0 13.562193320800688 -6.7614116936409845 24.999993392719922 0.9123637392140217 1.1188430261212337 0.3576835952014993 0.13797657188131116 0.8895203523992044 802512.4011744583 0.04805101121255875 0.045143570762018644 1.7321612003153932e-07 6.7614116936409845 0.20647928690721196 SKTDNSSLS(ph)SPLNPK ddPTM_PC-9_AZD4547_30min_R2 1 SKTDNSSLSSPLNPK 15 1 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 SKTDNSS(0.002)LS(0.592)S(0.405)PLNPK 63.614 0.018169 10571000.0 39813.0 44488.0 67794.0 95250.0 82387.0 65490.0 48898.0 65727.0 63493.0 82666.0 True False 52472.70583815581 58867.87598974355 66895.00726418733 73291.58409783039 70948.9871531367 61394.8999471458 53249.82727202225 55570.402406204914 66849.11035647147 79771.88850157207 0.6577844253633499 0.7379526434125154 0.8385787088752327 0.9187645607310152 0.8893983643340535 0.7696307696907023 0.6675262209816288 0.696616357592058 0.8380033569739805 1.0 16.28359281190523 -4.975292245877271 3.1579159561909727 0.8137643634011829 0.659384979783317 0.23938188218522938 0.0948360273512523 0.45063552737619095 8.623972013069055 0.026413806223339737 0.13763841277209288 1.0585411708740321e-05 4.975292245877271 -0.15437938361786585 SKTDNSSLSS(ph)PLNPK ddPTM_PC-9_AZD4547_30min_R2 1 SKTDNSSLSSPLNPK 15 1 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 SKTDNSSLS(0.028)S(0.972)PLNPK 107.62 0.00038666 10794000.0 70183.0 70538.0 86272.0 125080.0 111720.0 82250.0 68967.0 90438.0 73993.0 99649.0 True False 92499.73410291335 93338.02905422881 85127.9769108765 96244.73846673605 96209.60642757289 77106.8944976751 75104.92939321778 76462.88515849425 77904.11892029668 96160.31884079505 0.9619324812769992 0.9706501619317748 0.8852713669951124 1.0008779050127814 1.0005125563992714 0.8018577249658959 0.7810386893325822 0.7951604786698735 0.8101483008732147 1.0 16.55315405918082 -6.766200764334652 24.999833043045463 0.821300903339937 0.9619184967591508 0.46816732592168386 0.06610486437262704 94.28549642936915 495045.94704249006 0.02201797292769154 0.020045965739224132 1.7131651676357e-07 6.766200764334652 0.14061759341921376 SKTDNSSLSS(ph)PLNPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SKTDNSSLSSPLNPK 15 1 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 SKT(0.001)DNS(0.001)S(0.002)LS(0.11)S(0.885)PLNPK;S(0.002)KT(0.022)DNS(0.018)S(0.015)LS(0.261)S(0.681)PLNPK 64.2 0.017189 10218600.0 93560.0 67706.0 68295.0 97254.0 117253.0 96665.0 103618.0 101134.0 86297.0 66658.0 True False 109397.86010576856 74427.40422663423 69923.41181022968 91805.1736817222 94278.11635770329 91595.71723099302 93802.55291064458 98479.3396603306 87558.93036711589 78742.56773556246 1.389310296219376 0.945199100905375 0.8880001480908045 1.1658900175827043 1.1972954282404549 1.1632300020821609 1.1912559573324732 1.2506493310079654 1.1119643781640574 1.0 16.26485613800731 -5.936598122278202 24.99999149978493 1.1687090024024274 1.0555511079156399 0.05440723990952778 0.138346866029316 136.2987140203443 53742.161477939524 0.03841526116428874 0.056979036931797525 1.1571825546358405e-06 5.936598122278202 -0.11315789448678748 SKTDNSSLSS(ph)PLNPK ddPTM_PC-9_Lapatinib_30min_R1 1 SKTDNSSLSSPLNPK 15 1 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 SKTDNSSLS(0.007)S(0.993)PLNPK 140.75 3.4913e-05 8469500.0 127540.0 79833.0 76934.0 67703.0 58084.0 70469.0 55624.0 55593.0 71190.0 49060.0 True False 125721.25621202846 79648.15159342492 70608.78349382806 72682.10447058713 54667.61331753771 67455.20514126227 58503.938549677725 58176.0537322244 63171.832536065944 57539.95563165914 2.184938358604767 1.384223375201937 1.2271261372849982 1.2631588549678445 0.9500809084298105 1.1723193805201275 1.0167532787857798 1.0110548938312922 1.0978776720034187 1.0 15.812276488182958 -1.8722882095030422 0.8489905742969394 1.0580921390104638 199.99999526404005 0.9401001259254996 0.08415237996425823 69.99266872895329 0.3831047993214435 0.02806439740334417 26634.187753489394 0.013418741617939708 1.8722882095030422 198.9419031250296 up SKTPS(ph)SPCPASK ddPTM_PC-9_AZD4547_30min_R2 1 SKTPSSPCPASK 12 1 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 SKT(0.027)PS(0.512)S(0.461)PCPASK 142.1 0.00038823 4705400.0 26478.0 19513.0 23406.0 45931.0 41047.0 37722.0 26174.0 39622.0 28429.0 35312.0 True False 34897.45322338657 25820.19565248753 23095.621146791294 35342.31757687607 35348.3325727943 35363.23737679394 28503.435294243347 33499.330322982205 29931.698901046188 34075.73762813629 1.0241143890769893 0.7577296178958671 0.6777731827504527 1.0371695533802316 1.0373460718164245 1.037783474057347 0.8364730238651709 0.9830845244952777 0.8783874094725869 1.0 15.05645726654138 -5.778115180472831 24.999754514361566 0.9718924714987729 0.8136580605994442 0.3147831803509249 0.1033288185836568 277.0805894370636 415388.35576342855 0.029834445378066905 0.04438559720964729 1.6668050958133749e-06 5.778115180472831 -0.15823441089932866 SKTPS(ph)SPCPASK ddPTM_PC-9_Lapatinib_30min_R1 3 SKTPSSPCPASK 12 1 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 S(0.106)KT(0.4)PS(0.451)S(0.043)PCPASK;S(0.001)KT(0.003)PS(0.498)S(0.498)PCPASK;SKT(0.005)PS(0.712)S(0.282)PCPASK 147.33 4.9102e-07 13616900.0 80549.0 58879.0 62292.0 58406.0 62481.8 55867.0 55860.0 53900.0 56427.0 42231.8 True False 79400.35648912258 58742.669293014995 57170.59221407366 62701.3720767044 58806.74336794516 53477.6986423378 58752.15747492085 56404.39077162408 50071.597057347855 49531.510359663735 1.6030271621554006 1.1859656381658092 1.1542267094005445 1.2658885550109455 1.1872592404497877 1.0796702594776448 1.1861571966673967 1.1387577395087334 1.010903901249172 1.0 15.596058993156031 -2.4635170397783686 1.274757993143334 1.1329856026117826 199.9641446731992 0.7645589826736237 0.0782195908714892 301.6705063049784 1.552727032367326 0.023076667864632177 174251.0227511628 0.003439402164358984 2.4635170397783686 198.8311590705874 SKTPSS(ph)PCPASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKTPSSPCPASK 12 1 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 SKT(0.009)PS(0.183)S(0.807)PCPASK 179.5 0.0037982 2720500.0 15519.0 10634.0 12719.0 18727.0 21313.0 22392.0 17974.0 17365.0 19741.0 16716.0 True False 18146.06018577832 11689.673242342333 13022.269197076112 17677.786903753167 17136.870646650663 21217.72410113688 16271.372599508992 16909.18714973836 20029.674778697194 19746.478476216813 0.9189517111941716 0.5919877438613517 0.6594729897161401 0.8952374432253714 0.8678443939910991 1.0745067342864234 0.8240138928622979 0.8563140597501595 1.014341610471025 1.0 14.269307770161207 -5.846573226004895 5.336328398747244 0.9285113784275564 0.710979869485136 0.44741626252540445 0.10682395356100796 0.18057437385602387 8.50451533144773 0.029940730082107674 0.04551161116768078 1.4237271730398415e-06 5.846573226004895 -0.21753150894242035 SKTPSS(ph)PCPASK ddPTM_PC-9_Lapatinib_30min_R1 1 SKTPSSPCPASK 12 1 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 S(0.001)KT(0.001)PS(0.344)S(0.655)PCPASK 71.545 0.012809000000000001 22905000.0 163160.0 91269.0 137160.0 123340.0 127670.0 107950.0 101890.0 93280.0 127180.0 93208.0 True False 160833.3084801205 91057.67223805057 125883.23425291086 132410.8350501784 120160.70160887743 103333.23014374073 107165.36564840098 97614.1293353819 112855.64913522762 109318.87860814693 1.4712308663229783 0.8329546863030531 1.151523285416591 1.2112348455823856 1.0991761271133504 0.9452459763527055 0.9803006307129695 0.8929302109407776 1.0323527882110668 1.0 16.73818304033663 -6.664047506465844 4.437572465095519 0.9641499984195512 1.1430823260015555 0.27732946108149437 0.14851524662622043 0.3102009090017271 10.805153175019685 0.048499128624911146 0.047972753540636084 2.1674669976651185e-07 6.664047506465844 0.17893232758200428 SKTS(ph)EDISQTSK ddPTM_PC-9_Lapatinib_30min_R1 1 SKTSEDISQTSK 12 1 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 S(0.003)KT(0.011)S(0.979)EDIS(0.007)QTS(0.001)K 202.32 6.6578e-06 3691900.0 15074.0 9226.4 13766.0 13048.0 12544.0 7236.9 7421.5 10043.0 10540.0 9530.6 True False 14859.041995766964 9205.036837668325 12634.212618296697 14007.593446852012 11806.186582452872 6927.394657037859 7805.748956321611 10509.634443774039 9352.874208879548 11177.951511273757 1.3293170918464412 0.8234994424858967 1.1302797838722236 1.253144946345881 1.0562030592587108 0.6197374044833788 0.6983165876546306 0.9402111319926846 0.8367252442852798 1.0 13.448368201423698 -6.607824611669614 7.496103267563741 0.808694599914665 1.1168336219319188 0.47348995299583463 0.15895538217124663 0.21322010072593706 16.10982031497255 0.05283410435242846 0.05280038127624378 2.4670354398480184e-07 6.607824611669614 0.30813902201725385 SKVGS(ph)TENIK ddPTM_PC-9_AZD4547_30min_R2 1 SKVGSTENIK 10 1 E7EVA0;H7C4C5;H0Y2V1;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 S(0.008)KVGS(0.864)T(0.127)ENIK 76.358 0.010968 221160000.0 154430.0 134100.0 208260.0 223820.0 216470.0 247530.0 169170.0 207510.0 194050.0 181690.0 True False 203535.52765645372 177445.20253157264 205498.3363253334 172221.75698452903 186416.87704418768 232051.90996972067 184225.80227428526 175444.09760542205 204307.08683907328 175329.08840213218 1.1608771226234158 1.0120693842004527 1.1720721199097635 0.9822771483846637 1.0632398693400191 1.3235220241235148 1.0507429426185557 1.0006559619076218 1.1652777568230868 1.0 17.41970584424847 -10.829503195488996 3.8723909888348693 0.9997937864575596 1.0999053658981073 0.08819266111963053 0.09918006794624003 71410304.3218902 43.21226712324967 131378.17343252405 0.023831314761559516 1.4808013596608277e-11 10.829503195488996 0.10011157944054772 SKVGS(ph)TENIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKVGSTENIK 10 1 E7EVA0;H7C4C5;H0Y2V1;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 S(0.004)KVGS(0.498)T(0.498)ENIK 58.07899999999999 0.037025999999999996 109480000.0 102340.0 92955.0 102770.0 142350.0 145470.0 140080.0 146890.0 134550.0 132030.0 121340.0 True False 119664.14069286358 102182.95808180644 105220.42655739555 134374.5910049271 116966.19776513266 132733.9582032536 132975.5158084942 131018.2050675093 133960.68897377985 143337.98147308838 0.8348390249609483 0.7128812407686321 0.7340721940970727 0.9374667455475214 0.8160167777100517 0.9260208413648849 0.9277060723326865 0.9140508588235414 0.934579150599598 1.0 17.129061417759075 -6.192462902517066 0.7302014773769023 0.9474112616304776 0.7469141566936844 0.6112073306946808 0.05618804276841268 0.5349794792837161 0.602084002968514 0.03263515233750892 0.06382827311851914 6.420030591385806e-07 6.192462902517066 -0.20049710493679318 SKVGS(ph)TENIK ddPTM_PC-9_Lapatinib_30min_R1 4 SKVGSTENIK 10 1 E7EVA0;H7C4C5;H0Y2V1;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 S(0.064)KVGS(0.871)T(0.064)ENIK;S(0.263)KVGS(0.704)T(0.033)ENIK;S(0.001)KVGS(0.958)T(0.041)ENIK;S(0.001)KVGS(0.99)T(0.008)ENIK 77.633 0.010144 707640000.0 1105480.0 1160590.0 1008960.0 1124660.0 1147440.0 1113827.0 943990.0 1195223.0 1190080.0 970981.0 True False 1089715.6524797948 1157902.7251614344 926007.2034982289 1207371.2481557808 1079949.8351538358 1066191.2156675523 992865.1832214552 1250757.4239560806 1056040.6583020284 1138813.7720991452 0.9568866123485237 1.0167621375241214 0.8131331269302657 1.0602007788598002 0.9483111827522009 0.9362296468388069 0.871841566678047 1.0982984703904595 0.9273163744371099 1.0 20.11910041467101 -7.753166141268028 24.99989662178768 1.0096055754343283 0.9455666311937275 0.13670051708707465 0.07492455766558528 358.2840015016366 1082664.3596962173 0.034417098368382894 0.01944440617139516 1.7653623443462335e-08 7.753166141268028 -0.06403894424060075 SKVGST(ph)ENIK ddPTM_PC-9_AZD4547_30min_R2 1 SKVGSTENIK 10 1 E7EVA0;H7C4C5;H0Y2V1;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 S(0.002)KVGS(0.349)T(0.65)ENIK 109.0 0.020061000000000002 71021000.0 28510.0 35354.0 41105.0 64364.0 64546.0 62300.0 45090.0 44188.0 47078.0 49841.0 True False 37575.58695516093 46781.48911484878 40559.92084247009 49525.87421388714 55584.90204506008 58404.37115143047 49102.92264909575 37359.75993922411 49566.4469683581 48096.0817604197 0.7812608757265435 0.9726673650440116 0.8433102938511836 1.029727836470955 1.1557054132173246 1.214327009887402 1.0209339482931565 0.7767734620321823 1.0305714135979456 1.0 15.553631746412451 -5.770633150295243 23.578738298097882 1.0354941047842021 0.8764382990398085 0.3017564419771679 0.11589387290340845 136.17291682160584 349236.5359338327 0.03621164255148219 0.05465835323202983 1.6957696167412996e-06 5.770633150295243 -0.1590558057443936 SKVS(ph)SPIEK ddPTM_PC-9_AZD4547_30min_R2 2 SKVSSPIEK 9 1 Q06190 Q06190 PPP2R3A Serine/threonine-protein phosphatase 2A regulatory subunit B subunit alpha 1 S(0.001)KVS(0.595)S(0.404)PIEK;SKVS(0.708)S(0.292)PIEK 110.64 0.011045000000000001 83739000.0 374232.0 337813.0 388890.0 550890.0 489520.0 394000.0 358441.0 432200.0 335170.0 422980.0 True False 493229.9914908366 447004.4459567357 383733.0645037881 423890.82166565617 421558.5977302665 369363.11771530623 390341.5546077736 365413.4209679708 352886.4019368838 408171.59894509224 1.2083888069762212 1.0951385326955767 0.9401268130745382 1.0385113093639777 1.0327974773839548 0.9049211622511576 0.9563172832617461 0.8952446027905206 0.8645540327864765 1.0 18.63881627589968 -1.5228787452816046 0.4660383244503554 0.9248084556322793 8.081379660591734 0.7115685844904447 0.05329573169685679 51.466678239374886 0.5972232276645437 0.033042539218485 353.9609039597018 0.029999999999912475 1.5228787452816046 7.156571204959455 SKYDEIFYNLAPADGKLS(ph)GSK ddPTM_PC-9_AZD4547_30min_R2 2 SKYDEIFYNLAPADGKLSGSK 21 2 Q9NZN4;Q9NZN4-2 Q9NZN4 EHD2 EH domain-containing protein 2 1 SKYDEIFY(0.002)NLAPADGKLS(0.767)GS(0.232)K;SKYDEIFYNLAPADGKLS(0.724)GS(0.276)K 71.376 0.00077956 14172400.0 86948.0 103480.0 151561.0 185828.0 189455.0 195070.0 186764.0 203467.0 190621.0 204690.0 True False 114595.65536925073 136927.88633830825 149551.20211180195 142988.2256139801 163152.44348134447 182872.2420627534 203385.63419019108 172025.850356525 200696.83689951568 197523.865402787 0.5801610612245229 0.6932219864120593 0.757129786858109 0.7239035410855349 0.8259885110523078 0.9258235286649728 1.0296762559574808 0.8709117250502014 1.0160637373628671 1.0 17.59166744883121 -6.064813578039493 0.5710396720627813 0.9984119174722115 0.5764271689435522 0.8729277480758515 0.05171259667066131 0.4209499492382578 0.25938653550831825 0.03780039157410052 0.09929931439549346 8.61363415176283e-07 6.064813578039493 -0.4219847485286593 SKYDEIFYNLAPADGKLS(ph)GSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKYDEIFYNLAPADGKLSGSK 21 2 Q9NZN4;Q9NZN4-2 Q9NZN4 EHD2 EH domain-containing protein 2 1 SKYDEIFYNLAPADGKLS(0.777)GS(0.223)K 68.168 0.0011026 8288700.0 72075.0 93964.0 100530.0 154820.0 147010.0 131920.0 152710.0 134430.0 142650.0 108760.0 True False 84275.87395386136 103292.12493355761 102927.01646214825 146145.93733321223 118204.44582011488 125001.88296811239 138244.203275343 130901.35494035833 144735.9863827136 128477.3270563135 0.6559591165600916 0.8039716212984658 0.8011298088185927 1.137523177682194 0.9200412907742401 0.9729489695354747 1.0760202320736991 1.0188673592421669 1.1265488604014442 1.0 16.971154257750918 -5.63879470620176 5.508417487347917 1.0303885615327117 0.7473376498463441 0.7667263536123126 0.07177023042452367 0.09792755904196558 4.309599512374567 0.019706026936764282 0.03463068148254716 2.2972343089436173e-06 5.63879470620176 -0.28305091168636765 SKYDEIFYNLAPADGKLSGS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SKYDEIFYNLAPADGKLSGSK 21 2 Q9NZN4;Q9NZN4-2 Q9NZN4 EHD2 EH domain-containing protein 2 1 SKYDEIFYNLAPADGKLS(0.446)GS(0.554)K 51.818999999999996 0.010789 8258700.0 40441.0 41420.0 44167.0 65562.0 61049.0 58104.0 62972.0 54187.0 58149.0 46521.0 True False 47286.862553841194 45531.90386475634 45220.10878428028 61888.77369487183 49086.8866939134 55056.923953753896 57006.83628220091 52764.64866587229 58999.31911789993 54954.889039966605 0.8604668916618365 0.8285323591799579 0.822858704189056 1.1261741180090905 0.8932214685796995 1.0018567031172256 1.0373387568982624 0.9601447585036259 1.0735954552649896 1.0 15.745960215227214 -5.736331516848042 24.9993104334625 1.0070648209614181 0.8364104915184384 0.645157748107653 0.05966000042697971 137.96369690508908 137366.11643459817 0.01536445178825064 0.026598048312381887 1.8351369645411986e-06 5.736331516848042 -0.17065432944297976 SKYDEIFYNLAPADGKLSGS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 SKYDEIFYNLAPADGKLSGSK 21 2 Q9NZN4;Q9NZN4-2 Q9NZN4 EHD2 EH domain-containing protein 2 1 SKY(0.001)DEIFY(0.012)NLAPADGKLS(0.38)GS(0.607)K 46.131 0.022155 1467200.0 26498.0 21649.0 25175.0 23905.0 26533.0 21268.0 17650.0 22216.0 18448.0 18020.0 True False 26120.13366086195 21598.87307061058 23105.208678310275 25663.053444742305 24972.381105885066 20358.417218129496 18563.830637886724 23248.236463495366 16370.191973947796 21134.73298985931 1.235886617228365 1.0219610099154777 1.09323399966285 1.2142596481846133 1.1815801561281662 0.9632682479545732 0.8783565255730397 1.100001427728003 0.7745634629877939 1.0 14.367328265438895 -6.80129301404573 7.340834128011429 0.9444439689901172 1.1427457804787315 0.532476450608818 0.09650836087272799 0.17388301618602525 25.471703330145033 0.03294376048207925 0.029354415938244713 1.5801815472046485e-07 6.80129301404573 0.19830181148861437 SLAALDALNT(ph)DDENDEEEYEAWK ddPTM_PC-9_AZD4547_30min_R2 2 SLAALDALNTDDENDEEEYEAWK 23 0 P55081 P55081 MFAP1 Microfibrillar-associated protein 1 1 SLAALDALNT(1)DDENDEEEYEAWK;SLAALDALNT(1)DDENDEEEYEAWK 125.74 1.1786e-06 0.0 16922.5 19169.5 18720.5 25204.2 25468.3 24029.2 17228.1 23675.3 19165.1 19772.1 True False 22303.502990133646 25365.665994996154 18472.253938242604 19393.761091008248 21932.46615985813 22526.650325392515 18761.367524747973 20016.826389271115 20178.128059672898 19079.88479715885 1.1689537556041647 1.3294454481597975 0.9681533266381813 1.0164506388369878 1.1495072634361005 1.1806491792207736 0.9833061218242624 1.0491062499628814 1.0575602669612336 1.0 14.219764840040181 -5.25990219277263 24.99712026532206 1.056900663672699 1.249199604336717 0.5331011461863503 0.07415916158430262 105.180052713183 1710357.054476075 0.019772550294992905 0.04698431290030909 5.4966464960033425e-06 5.25990219277263 0.1922989406640181 SLAALDALNT(ph)DDENDEEEYEAWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLAALDALNTDDENDEEEYEAWK 23 0 P55081 P55081 MFAP1 Microfibrillar-associated protein 1 1 SLAALDALNT(0.998)DDENDEEEY(0.002)EAWK;SLAALDALNT(0.999)DDENDEEEY(0.001)EAWK;SLAALDALNT(0.996)DDENDEEEY(0.004)EAWK;SLAALDALNT(0.999)DDENDEEEYEAWK 75.797 0.01385 0.0 18451.4 20758.2 17499.1 23667.199999999997 25371.500000000004 22805.7 24475.0 24737.100000000002 20820.8 19047.9 True False 21574.8575882383 22818.936909835487 17916.3449097063 22341.20351409768 20400.136705836678 21609.728944859642 22156.55081634486 24087.77733612397 21125.2648109163 22501.13348690658 0.9588342560961527 1.0141238850528946 0.7962418835536365 0.9928923592715023 0.9066270691522064 0.9603840160956493 0.9846859861187779 1.0705139521144862 0.9388533614632836 1.0 14.457710058091767 -7.205422718297622 2.833205549862128 1.0061254285183066 0.9340719253073597 0.1887336682711389 0.06272315748491261 0.43693903773178566 6.929088734781366 0.026887499202158074 0.019016576211836136 6.231280217595519e-08 7.205422718297622 -0.07205350321094683 SLAALDALNT(ph)DDENDEEEYEAWK ddPTM_PC-9_Lapatinib_30min_R1 9 SLAALDALNTDDENDEEEYEAWK 23 0 P55081 P55081 MFAP1 Microfibrillar-associated protein 1 1 SLAALDALNT(1)DDENDEEEYEAWK;SLAALDALNT(1)DDENDEEEYEAWK;S(0.001)LAALDALNT(0.863)DDENDEEEY(0.136)EAWK;SLAALDALNT(0.993)DDENDEEEY(0.007)EAWK;SLAALDALNT(1)DDENDEEEYEAWK;SLAALDALNT(1)DDENDEEEYEAWK;SLAALDALNT(1)DDENDEEEYEAWK;SLAALDALNT(1)DDENDEEEYEAWK;SLAALDALNT(1)DDENDEEEYEAWK 133.84 1.9561e-07 1519400.0 92285.8 76455.59999999999 86444.3 79242.79999999999 81395.29999999999 79118.3 75456.5 68968.50000000001 80339.29999999999 59765.5 True False 90969.78756885712 76278.57175561792 79337.18333864793 85070.57985823172 76607.78848331684 75734.59474276537 79363.26835850997 72173.02829188782 71290.64202366573 70095.88704247694 1.2977906608661782 1.088203245211725 1.1318379249637132 1.2136315474070591 1.0928999077634012 1.0804427754351902 1.132210058350744 1.0296328548942133 1.017044580382652 1.0 16.097042174462906 -1.5228787452803376 0.13796181521950263 0.9537889091282041 1.885611816268306 0.615267139818807 0.053998682116580494 55.42538788892592 0.5129168480076809 0.24636486761764143 10.150835150096185 0.029999999999999995 1.5228787452803376 0.9318229071401019 SLAASS(ph)PPPCSQPSQCPEEKPQESSPMK ddPTM_PC-9_AZD4547_30min_R2 1 SLAASSPPPCSQPSQCPEEKPQESSPMK 28 1 Q7Z6J9 Q7Z6J9 TSEN54 tRNA-splicing endonuclease subunit Sen54 1 S(0.008)LAAS(0.183)S(0.696)PPPCS(0.102)QPS(0.011)QCPEEKPQESSPMK 56.68 0.0042313 4575200.0 12675.0 15380.0 14937.0 19355.0 17119.0 18039.0 14522.0 19491.0 14867.0 16104.0 True False 16705.38634362204 20351.284227707594 14738.925620337583 14893.00378176909 14742.322345449507 16911.018478341175 15814.429867158313 16479.113808622627 15652.83926841796 15540.203861676106 1.0749785840853354 1.309589269796914 0.94843837001942 0.9583531795549295 0.948656946631552 1.088210851599293 1.0176462296069666 1.0604181229090552 1.0072480005889515 1.0 13.923717809183104 -5.273031188604783 24.99493155072743 1.0057214417082112 1.1922839339031746 0.5515468587653501 0.06802650977810262 463.0746348422061 998509.0412637441 0.017517442637520395 0.036937511363037516 5.33296595728586e-06 5.273031188604783 0.18656249219496335 SLAASS(ph)PPPCSQPSQCPEEKPQESSPMK ddPTM_PC-9_Lapatinib_30min_R1 1 SLAASSPPPCSQPSQCPEEKPQESSPMK 28 1 Q7Z6J9 Q7Z6J9 TSEN54 tRNA-splicing endonuclease subunit Sen54 1 S(0.003)LAAS(0.2)S(0.387)PPPCS(0.34)QPS(0.069)QCPEEKPQESSPMK 51.096000000000004 0.020437 4243100.0 7237.4 13781.0 13885.0 12453.0 14078.0 16913.0 14810.0 15311.0 13313.0 13534.0 True False 7134.19334882339 13749.090941202112 12743.428897649976 13368.835161990202 13249.959718412923 16189.670416128634 15576.789334113466 16022.404955553546 11813.549747895013 15873.333867078574 0.44944517695931324 0.8661753766622298 0.8028199371576221 0.8422197424900938 0.8347307395766084 1.019928803343962 0.981318068690022 1.0093912904323235 0.7442387243171652 1.0 13.95431754794756 -4.508459910612632 1.638857811115352 0.9116643897923605 8.393703441961982e-41 0.6770187691563325 0.09306901073337241 1.3569133561752658 2.0187982244411935 0.026422568808886857 2.436620498409451 3.1012736514893663e-05 4.508459910612632 -0.9116643897923605 SLAASSPPPCS(ph)QPSQCPEEKPQESSPMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLAASSPPPCSQPSQCPEEKPQESSPMK 28 1 Q7Z6J9 Q7Z6J9 TSEN54 tRNA-splicing endonuclease subunit Sen54 1 SLAAS(0.096)S(0.381)PPPCS(0.428)QPS(0.095)QCPEEKPQESSPMK 72.399 0.00012714 4240400.0 20632.0 25799.0 20963.0 26688.0 26322.0 20845.0 25201.0 19305.0 17256.0 18393.0 True False 24124.59009942512 28360.154220348864 21462.837422620207 25192.757883663395 21164.39305405801 19751.851504474715 22813.77884056004 18798.264205338273 17508.336354855306 21727.505301092126 1.110324897640803 1.3052650926714238 0.9878187635992147 1.1594869054017485 0.9740829773491847 0.9090713006744449 1.0499953181193478 0.8651828152766984 0.8058143865221037 1.0 14.407234916868722 -6.105968201998156 0.731960879661093 0.9022250014875812 1.2086157166336553 0.5263389625800659 0.09622323850985537 0.619132367568789 0.6805476581687794 0.05312216230977466 0.11652628853144698 7.834870057083303e-07 6.105968201998156 0.3063907151460741 SLAPDRS(ph)DDEHDPLDNTSRPR ddPTM_PC-9_AZD4547_30min_R2 3 SLAPDRSDDEHDPLDNTSRPR 21 2 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614;Q92614-5;Q92614-2 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 S(0.034)LAPDRS(0.958)DDEHDPLDNT(0.004)S(0.004)RPR;S(0.075)LAPDRS(0.924)DDEHDPLDNTSRPR;S(0.331)LAPDRS(0.669)DDEHDPLDNTSRPR 55.718 0.005381800000000001 115036000.0 146646.0 145038.3 182425.0 301522.0 251725.0 207353.0 177677.0 251330.0 181104.0 232520.0 True False 193276.37757371197 191919.09409645808 180005.92530562234 232010.761368462 216777.32883978455 194387.1841310203 193489.90879404248 212492.72348884773 190676.78770885637 224379.54557357973 0.8613814466895413 0.8553323949643304 0.802238567893854 1.0340103006063883 0.9661189405016322 0.8663320162901205 0.8623330985871537 0.9470235931963147 0.8497957655695877 1.0 17.775581640381013 -13.575793164459697 0.01218974118785431 1.9928289336449139 1.2276408373789517e-06 0.1617200431914415 0.06631437543549942 16277.05809247635 17.526546695258986 1675.9366516914067 1221.7444862415111 2.6558701360552e-14 13.575793164459697 -1.9928277060040764 SLAPDRS(ph)DDEHDPLDNTSRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLAPDRSDDEHDPLDNTSRPR 21 2 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614;Q92614-5;Q92614-2 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 S(0.017)LAPDRS(0.983)DDEHDPLDNTSRPR;S(0.064)LAPDRS(0.936)DDEHDPLDNTSRPR;S(0.011)LAPDRS(0.986)DDEHDPLDNT(0.001)S(0.001)RPR;S(0.044)LAPDRS(0.955)DDEHDPLDNTSRPR 74.993 0.00060246 63480100.0 94584.8 104037.3 120023.0 130880.0 157357.0 124405.0 130973.0 121131.0 117790.0 106182.2 True False 110596.13850504607 114365.43558543714 122884.80350976242 123547.2179186852 126524.0254466761 117880.98279751385 118566.28927759481 117951.43959890334 119512.45591321315 125432.19232216751 0.8817205253096778 0.9117710012728961 0.9796911082773534 0.9849721640945187 1.0087045686142857 0.9397984729051161 0.9452620342715696 0.9403601851743916 0.9528052862717272 1.0 16.936548139507543 -5.093870817143504 3.6194773684747363 0.9668082035475746 0.8861977520896079 0.6103825218200849 0.023520111330798718 0.16939612484015237 3.999620026772558 0.006695437607369846 0.022975757191595753 8.056180402895702e-06 5.093870817143504 -0.08061045145796664 SLAPDRS(ph)DDEHDPLDNTSRPR ddPTM_PC-9_Lapatinib_30min_R1 4 SLAPDRSDDEHDPLDNTSRPR 21 2 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614;Q92614-5;Q92614-2 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 SLAPDRS(1)DDEHDPLDNTSRPR;SLAPDRS(0.956)DDEHDPLDNT(0.022)S(0.022)RPR;S(0.02)LAPDRS(0.98)DDEHDPLDNTSRPR;S(0.211)LAPDRS(0.786)DDEHDPLDNT(0.002)S(0.002)RPR 110.91 8.699100000000001e-05 143809800.0 140074.0 118377.0 150214.0 112854.0 132272.0 123806.0 105078.0 116388.0 128120.0 105509.0 True False 138076.51907357454 118102.90532956138 137863.9847628084 121153.6596299078 124492.02101675769 118511.1059858821 110518.42468939738 121795.81137528333 113689.77643658884 123746.09006809455 1.1158051054186382 0.9543970663200118 1.1140876021775323 0.9790504052551462 1.006027915292133 0.9576957617058304 0.893106397370468 0.9842396742253592 0.9187342919200764 1.0 16.91702341636858 -6.313422498908605 1.3934846677209878 0.9464285028504529 1.0493305975964062 0.4022088739087204 0.05382246598816553 0.4151870489912021 1.6277473303382837 0.019764253670907787 0.026383771403467118 4.859342395542826e-07 6.313422498908605 0.10290209474595335 SLAQVEEPAIENVKPPGS(ph)PVAK ddPTM_PC-9_AZD4547_30min_R2 4 SLAQVEEPAIENVKPPGSPVAK 22 1 Q9NXL9-4;Q9NXL9 Q9NXL9-4 MCM9 DNA helicase MCM9 1 SLAQVEEPAIENVKPPGS(1)PVAK;SLAQVEEPAIENVKPPGS(1)PVAK;SLAQVEEPAIENVKPPGS(1)PVAK;SLAQVEEPAIENVKPPGS(1)PVAK 100.53 4.3731000000000005e-05 55987000.0 137111.0 129344.0 154419.0 186204.0 187491.0 170005.0 153309.0 170885.0 150028.0 172419.0 True False 180709.44591403287 171151.91854022184 152371.30316441794 143277.5446231222 161461.11098023696 159374.5604751032 166953.20400111412 144478.6497966485 157958.17379176768 166382.66329025896 1.0861074245384597 1.0286643761774794 0.915788340871802 0.8611326552284521 0.9704202817006468 0.9578796091096947 1.0034290874996985 0.8683515874764047 0.9493667829815025 1.0 17.344145590078078 -5.073369905222208 3.5413374246571534 0.9374487711332119 1.0785149250201906 0.520421255032409 0.0460873129459092 0.17912532922631674 4.212074002880935 0.012190771007465809 0.04400094829818764 8.445591953556874e-06 5.073369905222208 0.14106615388697874 SLAQVEEPAIENVKPPGS(ph)PVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLAQVEEPAIENVKPPGSPVAK 22 1 Q9NXL9-4;Q9NXL9 Q9NXL9-4 MCM9 DNA helicase MCM9 1 SLAQVEEPAIENVKPPGS(1)PVAK;SLAQVEEPAIENVKPPGS(1)PVAK 74.3 0.00045464 29423000.0 24894.0 21603.0 26865.0 29451.0 43877.0 35794.0 38120.0 38863.0 36615.0 31876.0 True False 29108.06252108807 23747.603070746783 27505.563486079856 27800.955951430256 35279.616823679935 33916.89962826427 34508.99763509974 37842.88742875221 37150.42510622552 37654.86646972285 0.77302259309545 0.6306649125908206 0.730465038514909 0.7383097739513741 0.936920513369692 0.9007308432639333 0.9164551854897 1.004993271166704 0.9866035545789829 1.0 15.200548708670672 -6.271426931066894 1.5349227379280204 0.9670068197815294 0.6952105910616849 0.8636660378038006 0.04657754599411877 0.13362334783211421 0.6278785379670432 0.017256318156617267 0.023371128415420446 5.352702040351777e-07 6.271426931066894 -0.27179622871984443 SLAQVEEPAIENVKPPGS(ph)PVAK ddPTM_PC-9_Lapatinib_30min_R1 3 SLAQVEEPAIENVKPPGSPVAK 22 1 Q9NXL9-4;Q9NXL9 Q9NXL9-4 MCM9 DNA helicase MCM9 1 S(0.001)LAQVEEPAIENVKPPGS(0.999)PVAK;SLAQVEEPAIENVKPPGS(1)PVAK;SLAQVEEPAIENVKPPGS(1)PVAK 94.40299999999999 8.4299e-05 31923600.0 84000.0 60835.0 59898.0 63143.0 76893.0 82681.0 74907.0 74686.0 80022.0 67789.0 True False 82802.14459628677 60694.1402951913 54973.4176529664 67786.74685887311 72370.30491745452 79144.92636882467 78785.3179372341 78156.18421464786 71009.07969098278 79506.23832683523 1.0414546875668131 0.7633884028783889 0.691435273632001 0.8525965796572404 0.9102468742132381 0.9954555520973679 0.9909325305187052 0.9830195197182194 0.8931258877960969 1.0 16.27878044309228 -6.389906247031531 2.73821928280561 0.9715903812433684 0.8201081304205414 0.33706162624659497 0.0882069978225338 0.3093190547819716 4.4953995604272645 0.0303114938388608 0.03506556091686269 4.07468230183619e-07 6.389906247031531 -0.15148225082282696 SLAS(ph)ETN ddPTM_PC-9_AZD4547_30min_R2 1 SLASETN 7 0 Q9Y3L3;A0A2R8Y5V0 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 SLAS(0.677)ET(0.323)N 85.67 0.025702999999999997 3805300.0 33547.0 35136.0 50414.0 52234.0 40410.0 33572.0 27809.0 28315.0 25556.0 29607.0 True False 44214.24817905238 46493.02487807115 49745.477420077594 40192.25830725532 34799.769027373935 31472.737532838266 30283.947126828636 23939.567363970556 26906.837986391965 28570.46794166944 1.5475507180814077 1.6273105842366 1.7411502507288246 1.4067763394465 1.2180328687098325 1.1015828511137518 1.0599737879217623 0.8379130300856987 0.9417709937872208 1.0 14.802237045211111 -6.416594640977271 1.1245672439341636 0.9426577942451726 1.6506955919519328 0.9292662595656832 0.07903725183649526 0.119362304433855 0.31698626606532143 0.037625952236295855 0.04787049267311873 3.8318222864988127e-07 6.416594640977271 0.7080377977067602 SLAS(ph)IEAK ddPTM_PC-9_AZD4547_30min_R2 2 SLASIEAK 8 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 S(0.02)LAS(0.98)IEAK;SLAS(1)IEAK 101.38 0.0046034 189550000.0 692590.0 716590.0 712280.0 940270.0 924670.0 828120.0 699790.0 897420.0 760960.0 698430.0 True False 912819.2132330732 948213.7038187911 702834.7018045165 723505.2785266868 796295.5314660213 776337.5254883261 762069.9543271409 758744.3596600564 801182.7920693691 673978.1782855473 1.3543750267331878 1.4068908079944649 1.042815219318189 1.073484723744507 1.1814856283501975 1.151873384778063 1.1307041961887843 1.1257699197177804 1.1887369916150734 1.0 19.362342355771432 -5.254633183765738 24.99908121663245 1.11956885756884 1.3806329478927097 0.7744987133170382 0.057891705969011886 237.3934369860991 871937.596848729 0.01468312790096189 0.03703923399265591 5.563739865780576e-06 5.254633183765738 0.2610640903238697 SLAS(ph)IEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLASIEAK 8 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 S(0.011)LAS(0.989)IEAK;S(0.006)LAS(0.994)IEAK;SLAS(1)IEAK 101.66 0.0045165 94169000.0 249882.0 229261.0 204342.0 294879.0 234104.0 259554.0 222542.0 211800.0 197931.0 215949.0 True False 292182.0872055329 252020.5169468348 209214.2882513508 278357.88564061624 188233.00172962566 245942.53132129676 201461.21069544475 206240.4744206497 200825.36642633635 255098.84424865607 1.14536813393294 0.9879328057683371 0.8201302866249776 1.0911765847488064 0.7378826128516155 0.9641068035634287 0.7897378417719197 0.8084727903338442 0.7872453010041199 1.0 17.96069683711491 -1.5228788159890796 0.5966360241421964 0.8501077043083484 18.68964411975414 0.3827159610092604 0.10621487213136382 165.1407058414024 1.294812531779293 0.045967685629903804 3836.677293877841 0.029999995115613538 1.5228788159890796 17.83953641544579 SLAS(ph)IEAK ddPTM_PC-9_Lapatinib_30min_R1 2 SLASIEAK 8 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 S(0.014)LAS(0.986)IEAK;S(0.174)LAS(0.826)IEAK 98.04 0.0056283 10753300.0 79480.0 48336.0 65316.0 68039.0 66141.0 59380.0 63040.0 64143.0 81785.0 106236.0 True False 78346.60062515303 48224.08096175496 59945.970607051204 73042.81503145039 62250.71641820916 56840.45582154076 66303.90274291106 67123.31794553406 72573.51206576983 124598.75104942797 0.6287912195369691 0.38703502688100466 0.4811121307569994 0.5862242953179724 0.49960947356137203 0.4561880062424728 0.532139384901286 0.5387158168134962 0.5824577811135533 1.0 16.926930081612312 -9.298379596495499 0.8958418765576088 1.004979542860273 0.5034426693134358 0.842168983632174 0.06287395144702587 1.2894244111690851 1.2063540998391262 0.07482489387128315 0.019676484629513123 5.030607147269541e-10 9.298379596495499 -0.5015368735468372 SLAS(ph)PAGLQDGSAQHHPK ddPTM_PC-9_AZD4547_30min_R2 2 SLASPAGLQDGSAQHHPK 18 0 F1LLU8;Q9NQG7-2;Q9NQG7-3;Q9NQG7;Q9NQG7-4 F1LLU8 HPS4 Hermansky-Pudlak syndrome 4 protein 1 S(0.098)LAS(0.899)PAGLQDGS(0.004)AQHHPK;S(0.146)LAS(0.818)PAGLQDGS(0.036)AQHHPK 84.70700000000001 0.0010872 12365800.0 37459.0 36172.0 71922.0 118267.0 114883.0 97877.0 59781.0 113884.0 72114.0 88366.0 True False 49370.18280439752 47863.89161798692 70968.26728699995 91002.37035693534 98933.47847492705 91756.73571731243 65101.39318885763 96285.8445939756 75925.79881635113 85272.33323651715 0.57897070398509 0.5613062267831744 0.8322543150092719 1.0671969078707506 1.1602060682509814 1.0760434508436598 0.7634527016903357 1.1291569133790513 0.8903919470076909 1.0 16.379790111984306 -5.444017846699816 2.927297748817189 1.0152290605394332 0.5669094509189058 0.7161784653383623 0.11046273106648011 0.13840534194339807 2.2835372693086256 0.03127153947221288 0.07378105535823745 3.5973455208401214e-06 5.444017846699816 -0.4483196096205274 SLAS(ph)PAGLQDGSAQHHPK ddPTM_PC-9_Lapatinib_30min_R1 1 SLASPAGLQDGSAQHHPK 18 0 F1LLU8;Q9NQG7-2;Q9NQG7-3;Q9NQG7;Q9NQG7-4 F1LLU8 HPS4 Hermansky-Pudlak syndrome 4 protein 1 S(0.197)LAS(0.802)PAGLQDGS(0.001)AQHHPK 54.728 0.023593 5425000.0 16188.0 12877.0 24169.0 10410.0 26713.0 31952.0 26056.0 23880.0 33990.0 19834.0 True False 15957.156151484383 12847.184097660527 22181.918115037974 11175.586126741999 25141.79385977868 30585.487443749906 27405.052187012865 24989.55197822602 30161.688269432238 23262.28047285625 0.6859669743086495 0.5522753503316818 0.9535573324774024 0.4804166186450338 1.0807966093055903 1.3148103634739847 1.1780896640374805 1.0742520281872299 1.2965920647645275 1.0 14.505704915122816 -6.397911028923511 5.483504639498093 1.1794875748013274 0.6823691037751869 0.7356230327782698 0.14427564364744525 0.11336633140579022 4.603547929644064 0.043012872343669406 0.048744733823225625 4.000266922253362e-07 6.397911028923511 -0.4971184710261405 SLASEAPSQPSLNGGS(ph)PEGVESQDGVDHFR ddPTM_PC-9_AZD4547_30min_R2 1 SLASEAPSQPSLNGGSPEGVESQDGVDHFR 30 0 P38935 P38935 IGHMBP2 DNA-binding protein SMUBP-2 1 SLASEAPS(0.002)QPS(0.061)LNGGS(0.933)PEGVES(0.003)QDGVDHFR 55.18600000000001 0.0011926999999999999 10731000.0 13263.0 12384.0 17330.0 27077.0 19241.0 20998.0 15290.0 22138.0 13648.0 16574.0 True False 17480.35811246226 16386.88581768081 17100.192876779154 20834.81598547982 16569.71927383573 19684.991740573638 16650.780379345168 18717.08078063146 14369.405417055781 15993.74930473297 1.09294936286699 1.024580634937894 1.0691797495987234 1.3026849169953072 1.0360121918962626 1.2307928157125942 1.0410804910151845 1.1702747382124206 0.8984388302749936 1.0 13.965220559098528 -8.261289230290426 24.99998309650834 0.9492194054486086 1.1202331848594917 0.37381041336658016 0.08890003618145567 13.897130835020274 2315012.172769923 0.0678321851935651 0.021821746032530606 5.479119464383637e-09 8.261289230290426 0.17101377941088314 SLASEAPSQPSLNGGS(ph)PEGVESQDGVDHFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLASEAPSQPSLNGGSPEGVESQDGVDHFR 30 0 P38935 P38935 IGHMBP2 DNA-binding protein SMUBP-2 1 SLASEAPSQPS(0.001)LNGGS(0.999)PEGVESQDGVDHFR;SLASEAPSQPS(0.002)LNGGS(0.998)PEGVESQDGVDHFR 139.15 1.8718e-15 19871400.0 31083.0 31330.0 48113.0 44544.0 52829.0 45275.0 49779.0 36966.0 44048.0 31577.0 True False 36344.73798276616 34440.235347243266 49260.1963895686 42048.3440935965 42477.536686149666 42900.69929791766 45063.57275124948 35995.68166871453 44692.11866937103 37301.66013660553 0.9743463923499665 0.9232896128782686 1.320589920372678 1.1272512788869915 1.1387572706037512 1.1501016078321291 1.2080849105969653 0.9649887307131032 1.1981267993354796 1.0 15.186952219615755 -5.221924305593541 24.997018247945924 1.1397459520356 0.9488178733163987 0.3837296906651614 0.09613524640571901 520.2116807352083 329081.59271679877 0.023401917811543663 0.06191343300920781 5.998956246395149e-06 5.221924305593541 -0.19092807871920126 SLASEAPSQPSLNGGS(ph)PEGVESQDGVDHFR ddPTM_PC-9_Lapatinib_30min_R1 3 SLASEAPSQPSLNGGSPEGVESQDGVDHFR 30 0 P38935 P38935 IGHMBP2 DNA-binding protein SMUBP-2 1 SLASEAPSQPS(0.014)LNGGS(0.986)PEGVESQDGVDHFR;SLASEAPSQPSLNGGS(1)PEGVESQDGVDHFR;SLASEAPS(0.003)QPS(0.292)LNGGS(0.704)PEGVESQDGVDHFR 155.74 1.1892e-15 17528500.0 63202.0 52455.0 72646.0 47596.0 54674.0 63678.0 47450.0 56586.0 67631.0 45192.0 True False 62300.72789017271 52333.54367032562 66673.32630166937 51096.368615601525 51458.18281321973 60954.64038066811 49906.728825366874 59215.19213734911 60013.68459399744 53003.37698544517 1.1754105386017313 0.9873624407874335 1.2579071390107464 0.9640210024661766 0.970847250494063 1.1500142792299135 0.9415763987843899 1.1171965920890234 1.132261527609407 1.0 15.693796660073378 -1.5228794184078518 0.8209149286946951 1.0552241072854938 27.51127201774739 0.08516667876555817 0.09949579524969339 1699.1691606633628 5.385983141423421 0.0342053579596757 83758.76750710713 0.029999953502034635 1.5228794184078518 26.456047910461898 SLATMDS(ph)PPHQK ddPTM_PC-9_AZD4547_30min_R2 3 SLATMDSPPHQK 12 0 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 S(0.002)LAT(0.107)MDS(0.891)PPHQK;S(0.001)LAT(0.123)MDS(0.876)PPHQK;SLAT(0.008)MDS(0.992)PPHQK 84.71799999999999 0.008856200000000002 50006400.0 198956.0 184504.0 265723.0 296502.0 257187.0 261231.0 196988.0 273134.0 243689.0 264839.0 True False 262219.8694581196 244141.3098276309 262199.33939967596 228148.04481023506 221481.02442076767 244896.18427382526 214519.550383679 230927.41629492285 256569.90303904668 255567.06722071808 1.0260315318000497 0.9552925284257403 1.025951200407328 0.8927130059883543 0.8666258404471484 0.958246251901944 0.8393865168801706 0.9035883175647376 1.0039239634012098 1.0 17.963342414718376 -5.763922808788344 24.999993261840366 0.9150541051446535 0.9977118362386966 0.30090261372636506 0.053925468545339465 73.62966816561242 741222.0085673196 0.014673964801714479 0.022963295091069428 1.7221746459581224e-06 5.763922808788344 0.08265773109404317 SLATMDS(ph)PPHQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLATMDSPPHQK 12 0 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 S(0.001)LAT(0.044)MDS(0.956)PPHQK;SLATMDS(1)PPHQK 126.56 0.00022885 8950000.0 36855.0 36597.0 37209.0 43354.0 42790.0 38734.0 42811.0 41850.0 32490.0 29678.0 True False 43093.82358056967 40230.10829885294 38096.20367591832 40925.01593556443 34405.60667058515 36702.72085269004 38755.632155200816 40751.4818437403 32965.10478495882 35058.38646908126 1.2292015668939877 1.1475173945707036 1.0866502287410225 1.1673388326544085 0.981380209865853 1.0469027399495112 1.1054596648188653 1.162388973025895 0.9402915566017691 1.0 15.097471978424363 -1.5228787452839905 0.4186987260237543 1.0456938387303472 4.363560348164539 0.4348498018309669 0.06648644868160739 81.89284626020515 1.0518863956062845 0.04561506850538062 227.3563934805107 0.029999999999747666 1.5228787452839905 3.3178665094341913 SLATMDS(ph)PPHQK ddPTM_PC-9_Lapatinib_30min_R1 3 SLATMDSPPHQK 12 0 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 SLAT(0.096)MDS(0.904)PPHQK;SLAT(0.005)MDS(0.995)PPHQK;SLAT(0.004)MDS(0.996)PPHQK 90.15 0.006256 17801600.0 92675.0 125959.0 139881.0 106270.0 123656.0 121958.0 114762.0 110861.0 123662.0 104015.0 True False 91353.43750548655 125667.34967439799 128380.52413627473 114085.4503063279 116382.79719704993 116742.14063798361 120703.81482522147 116012.00677797789 109733.88334140995 121993.85415872459 0.7488363912712177 1.0301121359023042 1.0523523912052204 0.9351737519325591 0.954005412810598 0.956950999237158 0.9894253743977574 0.950965993967501 0.8995033733308946 1.0 16.896448943552286 -4.752441899726713 24.999366467008002 0.9732606949606002 0.7488359594136821 0.7121078473343023 0.042998220951037454 204.40146560591506 567884.9892470352 0.011335384656585318 0.13502671764557958 1.7683087677136046e-05 4.752441899726713 -0.2244247355469181 SLDDVIKR ddPTM_PC-9_Lapatinib_30min_R1 1 SLDDVIKR 8 1 P00352 P00352 ALDH1A1 Retinal dehydrogenase 1 0 77.318 0.015004 48204000.0 89323.0 108030.0 114760.0 109240.0 103020.0 94369.0 108630.0 95919.0 106050.0 102230.0 False True 88049.23764016785 107779.8631723433 105324.87578641053 117273.8740139572 96960.56614511296 90333.05785488355 114254.32986932796 100375.74690952526 94105.53224399194 119900.3192870874 0.7343536544664586 0.8989122282008017 0.8784369917666552 0.9780947599743961 0.8086764632623882 0.7534013119564054 0.9529109726201748 0.8371599634291813 0.7848647343354204 1.0 16.87147597500116 -10.674216349265686 4.030213648238757 1.0000555576208683 0.8525889979875737 0.25917754834299733 0.07694211498730985 110329119.0590096 169209284.6865507 75430.36523005049 0.019252378232131134 2.1173061097791647e-11 10.674216349265686 -0.14746655963329458 SLDGSGS(ph)EPAVCEMCGIVGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLDGSGSEPAVCEMCGIVGTR 21 0 H7C228;Q969R5-2;Q969R5-3;Q969R5 H7C228 L3MBTL2 Lethal(3)malignant brain tumor-like protein 2 1 S(0.284)LDGS(0.07)GS(0.646)EPAVCEMCGIVGTR 109.07 4.2915e-05 4291000.0 21713.0 20919.0 24587.0 24879.0 27033.0 25052.0 32549.0 24053.0 23422.0 20942.0 True False 25388.58204870191 22995.7000711453 25173.247326716755 23485.110288806278 21736.07770801423 23738.229018474503 29465.723085646914 23421.6342362601 23764.502439929376 24738.618823219203 1.0262732220471686 0.9295466426590464 1.0175688265623632 0.9493298901054086 0.8786293957370471 0.9595616144986335 1.1910819798068493 0.9467640212103108 0.9606236552553394 1.0 14.59447733529963 -7.056570071285202 24.999909224096665 1.0280582997575047 0.9569330889116499 0.15468648587582545 0.07344672948777842 527.1191552812564 232946.90508250322 0.02846761448752272 0.0220510051955952 8.778694357404142e-08 7.056570071285202 -0.07112521084585488 SLDGSGS(ph)EPAVCEMCGIVGTR ddPTM_PC-9_Lapatinib_30min_R1 1 SLDGSGSEPAVCEMCGIVGTR 21 0 H7C228;Q969R5-2;Q969R5-3;Q969R5 H7C228 L3MBTL2 Lethal(3)malignant brain tumor-like protein 2 1 S(0.43)LDGS(0.001)GS(0.569)EPAVCEMCGIVGTR 184.2 5.1808e-15 4089900.0 10718.0 13279.0 13038.0 14171.0 14004.0 12274.0 12269.0 11453.0 15626.0 7678.5 True False 10565.159354559526 13248.253291359331 11966.065968135425 15213.182613070194 13180.312252923324 11749.06963209146 12904.228787321952 11985.148191232098 13866.035330925208 9005.718494041881 1.1731611821476942 1.4710934280395596 1.3287186331720326 1.6892802748759166 1.4635492172715951 1.3046232390968648 1.4328927554041688 1.3308375338582241 1.5396922899709642 1.0 13.13662566645053 -11.197433424439184 2.709849902411054 0.9451074968635765 1.4183100230988877 0.4597511354769217 0.1348719984496834 26981056.25496998 23729708.03847979 10218532.42521063 0.03424786300331217 6.346971899971841e-12 11.197433424439184 0.4732025262353111 SLDLFNCEVTNLNDYR ddPTM_PC-9_AZD4547_30min_R2 1 SLDLFNCEVTNLNDYR 16 0 P39687;H0YN26;Q92688;Q92688-2 P39687;Q92688 ANP32A;ANP32B Acidic leucine-rich nuclear phosphoprotein 32 family member A;Acidic leucine-rich nuclear phosphoprotein 32 family member B 0 201.48 7.7054e-12 4695500.0 4799.2 6941.4 11940.0 12089.0 11922.0 10378.0 9581.1 9611.2 7568.7 11355.0 False True 6325.245770438734 9185.071803524672 11781.667798542592 9302.067823188145 10266.836088699625 9729.062019414861 10433.799338949902 8126.009883404333 7968.766030192706 10957.46490619301 0.5772544858312794 0.8382478869116335 1.0752183921559952 0.8489251759255686 0.9369718430854338 0.8878935139382584 0.9522092407572176 0.7415957936412484 0.7272454074380715 1.0 13.419626437856015 -4.786376730587319 4.318366509961943 0.8922545293373708 0.5558150815925412 0.46757232006096006 0.10144537183554854 0.18153732046839471 6.8933454702723305 0.02620968821789917 0.18282695239700425 1.6353972736605394e-05 4.786376730587319 -0.3364394477448296 SLDLFNCEVTNLNDYR ddPTM_PC-9_Lapatinib_30min_R1 2 SLDLFNCEVTNLNDYR 16 0 P39687;H0YN26;Q92688;Q92688-2 P39687;Q92688 ANP32A;ANP32B Acidic leucine-rich nuclear phosphoprotein 32 family member A;Acidic leucine-rich nuclear phosphoprotein 32 family member B 0 ; 244.23 3.2717e-46 18404200.0 44503.0 55155.0 53199.0 49813.0 51907.0 52151.0 55234.0 50740.0 54624.0 53214.0 False True 43868.37905914933 55027.29198621312 48825.18357407858 53476.4141912967 48853.932313088444 49920.62329991866 58093.74625796241 53097.56563547691 48471.66990377952 62411.96899680203 0.7028840743895955 0.8816785124826408 0.7823048104215454 0.8568294679829251 0.7827654390392923 0.7998565676156857 0.9308109837223548 0.8507593413404023 0.7766406136980423 1.0 15.929535106657562 -14.522878745279572 0.17726805144668906 1.6970173134210786 0.786148967059017 0.4595857700348348 0.0601226215172175 123.89226889625144 1.1830083644505436 30.51664256872835 0.18998593587899051 3.00000000000529e-15 14.522878745279572 -0.9108683463620616 SLDLLAALPT(ph)PPHNQTEDVR ddPTM_PC-9_AZD4547_30min_R2 2 SLDLLAALPTPPHNQTEDVR 20 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 SLDLLAALPT(1)PPHNQTEDVR;SLDLLAALPT(1)PPHNQTEDVR 116.94 3.581e-05 6362400.0 34041.0 38240.0 44389.0 39432.0 42981.0 49288.0 45575.0 53562.0 46321.0 40780.0 True False 44865.329903214064 50600.33217604284 43800.37285674262 30341.56161832697 37013.8300560643 46206.01356840619 49631.08670952625 45285.22363231467 48769.43349380428 39352.30461246598 1.140094089661058 1.2858289412613897 1.1130319631360952 0.7710237536816434 0.9405759185026001 1.174162835529818 1.2611989869026416 1.150764207541971 1.2393031100484813 1.0 15.264160507165725 -6.885553171498536 10.956896789453538 1.1813792627664446 1.051265514829897 0.13641436359798087 0.14180215260347828 0.7520257711438271 68.94658206925267 0.05548373334859802 0.04893859866965525 1.3015079597320974e-07 6.885553171498536 -0.1301137479365475 SLDLLAALPT(ph)PPHNQTEDVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLDLLAALPTPPHNQTEDVR 20 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 SLDLLAALPT(1)PPHNQTEDVR;SLDLLAALPT(1)PPHNQTEDVR 121.39 2.115e-05 7326200.0 36282.0 43668.0 40282.0 37259.0 44281.0 37465.0 46354.0 21463.0 26687.0 31452.0 True False 42423.82599783553 48003.07044824195 41242.475650335735 35171.49902530783 35604.455923818205 35500.26944663688 41963.01354610212 20899.618991928277 27077.246888156213 37153.99862610498 1.1418374217204144 1.2920028051708612 1.1100413730800467 0.9466410164691071 0.9582940528721977 0.9554898734827921 1.1294346530071262 0.5625133165947818 0.728784192534564 1.0 15.18122986588837 -5.998710028306671 0.5579890358879492 0.8058506812363868 1.2838510520193194 0.443485138567811 0.1497034999647325 1.2158096757434658 0.6860416406915412 0.11178471700970055 0.32435469132274825 1.0029746852129468e-06 5.998710028306671 0.47800037078293256 SLDLLAALPT(ph)PPHNQTEDVR ddPTM_PC-9_Lapatinib_30min_R1 2 SLDLLAALPTPPHNQTEDVR 20 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 SLDLLAALPT(1)PPHNQTEDVR;SLDLLAALPT(1)PPHNQTEDVR 97.352 0.00094415 8704700.0 49777.0 49229.0 47457.0 42341.0 55280.0 52445.0 47992.0 48859.0 49210.0 45873.0 True False 49067.1708520162 49115.01327512071 43555.2686493176 45454.89838543541 52028.539084661585 50202.049605266184 50476.79093334052 51129.16750854876 43667.451595726976 53802.08692806972 0.9119938213106151 0.9128830511869297 0.8095460815032784 0.8448538148010127 0.9670357054034118 0.9330874036983625 0.9381939217492635 0.9503194100426903 0.8116311854985817 1.0 15.715374514085683 -6.254571708875827 24.950681216991097 0.9311201808827806 0.8685899598940792 0.25226044399901915 0.053506870667956175 805.3539998057473 2925899.056936756 0.016051718169979225 0.02026747741548139 5.564527475383119e-07 6.254571708875827 -0.06253022098870142 SLDNNY(ph)STPNER ddPTM_PC-9_AZD4547_30min_R2 3 SLDNNYSTPNER 12 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-25;O60716-27;O60716-29;O60716-26;H0YC95 O60716 CTNND1 Catenin delta-1 1 SLDNNY(0.922)S(0.077)TPNER;SLDNNY(0.655)S(0.336)T(0.009)PNER;SLDNNY(0.959)S(0.04)T(0.001)PNER 196.67 1.7344000000000002e-05 21817700.0 58956.0 59391.0 69907.0 101649.0 94187.0 82164.0 64165.0 76333.0 65239.0 74441.0 True False 77702.78163902018 78587.97929569449 68979.98750357766 78215.39351139482 81110.760835963 77026.27209127022 69875.56069592429 64537.488807839094 68687.40035194179 71834.8432480768 1.0816865204351995 1.0940091986321483 0.9602580639782274 1.0888224985928239 1.1291283890723118 1.072268952063627 0.9727251781508556 0.8984148344970033 0.956185010590675 1.0 16.132396167720778 -7.335307468132713 4.093350766034202 0.9444177313273642 1.0707016516850718 0.5860295418197023 0.047031688890150365 0.16553557287057216 5.338610198383776 0.021489915483961612 0.014226000598788256 4.620537846467779e-08 7.335307468132713 0.12628392035770764 SLDNNY(ph)STPNER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLDNNYSTPNER 12 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-25;O60716-27;O60716-29;O60716-26;H0YC95 O60716 CTNND1 Catenin delta-1 1 SLDNNY(0.888)S(0.11)T(0.002)PNER;SLDNNY(0.999)S(0.001)TPNER;SLDNNY(0.696)S(0.296)T(0.008)PNER 165.63 9.1215e-05 15688500.0 40727.0 38057.0 61518.0 45080.0 71330.0 55794.0 52000.0 45805.0 47071.0 39233.0 True False 47621.2767050837 41835.04745004906 62984.82242831416 42554.313751331916 57353.39854668944 52868.064420276474 47074.18355260195 44602.6672844092 47759.32432541696 46345.6323317429 1.0275245866581282 0.9026750816688186 1.359023909253576 0.9181946951705685 1.2375146407789357 1.1407345581530939 1.0157199542697803 0.9623920322230687 1.0305032410293773 1.0 15.500145763486719 -7.3954918106799585 5.6609220229050985 0.9959834317567318 1.098516997848139 0.11640525875493957 0.12933561176356173 0.518430692659369 21.69394758497496 0.05416824060833552 0.0359868788402839 4.022612412090017e-08 7.3954918106799585 0.10253356609140729 SLDNNY(ph)STPNER ddPTM_PC-9_Lapatinib_30min_R1 2 SLDNNYSTPNER 12 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-25;O60716-27;O60716-29;O60716-26;H0YC95 O60716 CTNND1 Catenin delta-1 1 SLDNNY(0.974)S(0.022)T(0.005)PNER;SLDNNY(0.692)S(0.289)T(0.02)PNER 126.34 0.00038618 10678000.0 54146.0 45158.0 53887.0 34674.0 37498.0 40747.0 38934.0 33192.0 48600.0 31382.0 True False 53373.86811083971 45053.439425499244 49456.618869835365 37224.0416290732 35292.44136390451 39004.34579589627 40949.8120144749 34734.22149335336 43126.15621931175 36806.33688611345 1.4501271418557538 1.224067463298618 1.3436984784132295 1.0113487181365595 0.9588686174640727 1.0597182196257107 1.1125750476387322 0.9437022108673392 1.1717046538141829 1.0 15.167666553634106 -5.760478314846954 24.999999999278895 1.0353590004177704 1.3277747324159228 0.7404198243194605 0.08197757352271884 12.367422462529493 321692.3877232521 0.021663052042514605 0.03492785694029921 1.7358879369080168e-06 5.760478314846954 0.2924157319981524 SLDNNYS(ph)TPNER ddPTM_PC-9_AZD4547_30min_R2 1 SLDNNYSTPNER 12 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-25;O60716-27;O60716-29;O60716-26;H0YC95 O60716 CTNND1 Catenin delta-1 1 SLDNNY(0.001)S(0.66)T(0.339)PNER 76.165 0.018953 26391000.0 36736.0 30221.0 46544.0 51990.0 55840.0 43111.0 35072.0 41728.0 41696.0 36038.0 True False 48417.28384373171 39989.34724613468 45926.79614869067 40004.5087374929 48087.57986856125 40415.26235488478 38193.34005653329 35279.89641404778 43899.9654359289 34776.32058911351 1.3922486054746233 1.1499016160626572 1.3206341375593296 1.150337587755504 1.3827679022379022 1.1621488895388348 1.0982570729029184 1.014480422782044 1.262352218183527 1.0 15.085817679973058 -6.977040928433964 9.806456009737888 1.0999336953506549 1.267785429483379 0.42702633822954117 0.1014242401608221 0.3203032256418979 130.0711620605425 0.0335762428319603 0.029410823163875464 1.0542875343849198e-07 6.977040928433964 0.16785173413272414 SLDNNYS(ph)TPNER ddPTM_PC-9_Lapatinib_30min_R1 1 SLDNNYSTPNER 12 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-25;O60716-27;O60716-29;O60716-26;H0YC95 O60716 CTNND1 Catenin delta-1 1 SLDNNY(0.225)S(0.436)T(0.339)PNER 175.49 0.001044 6523000.0 17019.0 16617.0 18170.0 13832.0 18846.0 13773.0 13109.0 11472.0 17572.0 14803.0 True False 16776.305939097638 16578.524357445433 16676.13273822831 14849.25142219935 17737.51533266159 13183.96089643114 13787.719877170377 12005.031000595005 15592.856318636752 17361.678826242358 0.9662836242391535 0.9548917776538304 0.960513836543397 0.8552889136363099 1.0216474748888427 0.7593713158950646 0.794146696017098 0.6914671743869191 0.8981191551054376 1.0 14.083618838690631 -6.768181871862367 24.999864614718803 0.8071829240397045 0.947031747626587 0.3185621482609844 0.08711620022952286 163.66014443627688 606816.71412564 0.02877943648319289 0.025952753878842376 1.7053680731808904e-07 6.768181871862367 0.13984882358688255 SLDNNYST(ph)PNER ddPTM_PC-9_AZD4547_30min_R2 1 SLDNNYSTPNER 12 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-25;O60716-27;O60716-29;O60716-26;H0YC95 O60716 CTNND1 Catenin delta-1 1 SLDNNYS(0.23)T(0.77)PNER 125.84 0.00068751 33504000.0 50216.0 54583.0 67957.0 67506.0 70687.0 61493.0 53480.0 81934.0 45271.0 53512.0 True False 66183.6434423135 72225.88732125897 67055.84577768504 51943.53465730325 60873.33019643603 57647.83298900348 58239.61639551208 69272.98295601505 47663.93263742173 51638.56116778513 1.2816709440696494 1.3986812507533093 1.298561467656036 1.0059059253902756 1.1788347471310265 1.1163717904860457 1.1278318969089527 1.3414971561839568 0.9230298358343303 1.0 15.656161182188738 -1.522878745280338 0.22391244082775058 1.0445588725448134 2.7811587235987316 0.37219341810492 0.12073331012578606 59.091773438332346 0.7627247559088953 0.18650794308463453 37.28690185458729 0.029999999999999964 1.522878745280338 1.7365998510539182 SLDNNYST(ph)PNER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLDNNYSTPNER 12 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-25;O60716-27;O60716-29;O60716-26;H0YC95 O60716 CTNND1 Catenin delta-1 1 SLDNNYS(0.003)T(0.997)PNER 179.83 0.001872 23022000.0 60697.0 72701.0 90032.0 61187.0 84394.0 55139.0 63449.0 44880.0 43107.0 43328.0 True False 70971.80327960491 79918.2748158293 92178.70432826123 57758.890760930466 67857.60152739804 52247.41377333804 57438.65138901998 43701.94755429067 43737.358324568144 51183.02341574071 1.386627802408765 1.5614215316411224 1.800962471082019 1.1284775088758714 1.325783375011201 1.020795769506457 1.1222207590682387 0.853836773168243 0.8545286191733108 1.0 15.643377750413794 -6.47105977434723 0.9181212756976591 0.9192342830183295 1.5716734783462838 0.7122093672093277 0.15774083316550655 0.30514837465199 0.5603185084207336 0.08463731979378779 0.10710279408117616 3.380183096780855e-07 6.47105977434723 0.6524391953279542 SLDNNYST(ph)PNER ddPTM_PC-9_Lapatinib_30min_R1 2 SLDNNYSTPNER 12 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-25;O60716-27;O60716-29;O60716-26;H0YC95 O60716 CTNND1 Catenin delta-1 1 SLDNNYS(0.003)T(0.997)PNER;SLDNNY(0.001)S(0.107)T(0.892)PNER 159.66 0.0013125 46830000.0 64404.0 82142.0 70469.0 60588.0 57812.0 44527.0 40567.0 45388.0 61617.0 39568.0 True False 63485.58714975288 81951.80524578932 64675.3108382064 65043.84363564303 54411.611822765124 42622.684007506665 42667.36076414455 47496.892177040325 54677.04460422491 46407.276078954084 1.36800934064182 1.765925780827176 1.3936459172516906 1.4015871891507272 1.1724801888866097 0.918448303989905 0.9194110141597902 1.0234794237057232 1.1781998260617843 1.0 15.50206339912793 -6.2234624592332315 1.6978834341089832 1.0033871308517064 1.540611093678468 0.7739018578366934 0.1216972946678892 0.16407663767298544 0.9357236547441495 0.043171856841225396 0.059518171308180476 5.977747145859642e-07 6.2234624592332315 0.5372239628267617 SLDQEIAR ddPTM_PC-9_AZD4547_30min_R2 1 SLDQEIAR 8 0 P48681 P48681 NES Nestin 0 111.04 0.017289 22238000.0 47100.0 50344.0 54483.0 98014.0 73358.0 49695.0 45638.0 66847.0 61200.0 60351.0 False True 62076.8202591399 66616.71346942206 53760.51982144017 75418.38660120455 63173.50795125203 46587.56379406641 49699.69358747908 56517.33214124449 64434.90705772373 58238.12985941476 1.0659136962157205 1.1438676624787398 0.9231154906796729 1.295000144806546 1.084744790118624 0.7999495160048494 0.8533875264788339 0.9704523870817242 1.1064041241239686 1.0 15.829676408062237 -6.592775390597982 11.465180200562127 0.9386180848429339 1.1081274781383113 0.3178466258985112 0.11473352337889248 0.685676664641138 109.59456379630846 0.038645454167139597 0.03864028559369828 2.55402185594612e-07 6.592775390597982 0.1695093932953774 SLDQEIAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLDQEIAR 8 0 P48681 P48681 NES Nestin 0 117.93 0.016241 23146000.0 68528.0 83104.0 73823.0 83534.0 87271.0 77932.0 82044.0 80341.0 76891.0 67255.0 False True 80128.4369103046 91354.01590479742 75583.22029528639 78853.86080088187 70170.87403011534 73845.1087285547 74272.19837287838 78232.13387832607 78015.38541151951 79447.79910971307 1.0085671070592102 1.149862134993098 0.9513570060123389 0.992524169133861 0.8832324471721765 0.9294796024063376 0.9348553289728332 0.9846985662912042 0.981970379113769 1.0 16.27771963364203 -5.282732091879938 24.92107019344502 0.9535407984808576 1.0792146157391829 0.5263163909389488 0.046168684093229176 481.0894093039318 563068.3327255282 0.011836361393310582 0.024681895076269496 5.215163255353533e-06 5.282732091879938 0.12567381725832527 SLDQEIAR ddPTM_PC-9_Lapatinib_30min_R1 3 SLDQEIAR 8 0 P48681 P48681 NES Nestin 0 ;; 125.25 0.015758 47901300.0 164946.0 164419.0 180099.0 149581.0 159875.0 165211.0 160191.0 141386.0 173117.0 128459.0 False True 162593.83979260846 164038.2979073729 165291.95542224456 160581.6857275885 150471.46682634362 158145.31065565106 168484.90615941744 147955.30971496901 153618.7404571726 150662.9669891415 1.0791891533924645 1.0887765001946057 1.09709744023664 1.0658338205908413 0.9987289500092501 1.049662792496638 1.118290111541215 0.9820283821015708 1.0196184472342438 1.0 17.200965319993607 -6.357167851114733 0.2368954222948233 0.9893160715772006 1.127948294618783 0.36765795974883186 0.03570435929550074 5.811910887062215 0.5841546189309027 0.07529365702319586 0.2458047741336158 4.393717691748948e-07 6.357167851114733 0.13863222304158251 SLDQTS(ph)PCPLVLVR ddPTM_PC-9_AZD4547_30min_R2 1 SLDQTSPCPLVLVR 14 0 Q6XZF7 Q6XZF7 DNMBP Dynamin-binding protein 1 SLDQT(0.041)S(0.959)PCPLVLVR 105.58 0.0034850000000000003 0.0 7076.0 6704.2 10021.0 12267.0 12764.0 11329.0 8347.1 13391.0 8642.0 8363.8 True False 9326.020810056769 8871.201542223489 9888.114992394914 9439.032673260735 10991.938922677573 10620.595839077941 9089.975729524664 11321.728644567536 9098.798477007324 8070.985907742585 1.1554995779524548 1.0991471975825466 1.225143384640176 1.1695018156587 1.361907832366909 1.3158982013448304 1.126253450746897 1.4027689769234362 1.1273465944574066 1.0 12.978529200709545 -5.45174018400423 2.1624252206816834 1.2391430782287822 1.1266471445700472 0.052616749331208856 0.11727203634182314 0.6996219212419628 6.300696555834676 0.031802099500977996 0.08677432610311796 3.5339452428683377e-06 5.45174018400423 -0.112495933658735 SLDSEPSVPSAAKPPS(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 4 SLDSEPSVPSAAKPPSPEK 19 1 Q7Z3K3-5;Q7Z3K3-7;Q7Z3K3-2;Q7Z3K3-3;Q7Z3K3-6;Q7Z3K3 Q7Z3K3-5 POGZ Pogo transposable element with ZNF domain 1 SLDSEPSVPSAAKPPS(0.999)PEK;SLDSEPSVPSAAKPPS(1)PEK;SLDSEPSVPSAAKPPS(1)PEK;SLDSEPSVPSAAKPPS(1)PEK 94.973 0.00034679999999999997 221447000.0 453092.0 498963.0 366392.0 343680.0 403809.0 427380.0 511068.0 392284.0 433460.0 451269.0 True False 597165.8311009392 660243.0319967276 361533.40268371964 264449.88580306893 347747.0906007134 400655.86103849637 556552.061930096 331665.52158953913 456371.8106738712 435470.209665593 1.3713127048564717 1.5161611916088187 0.8302138577087718 0.6072743437631376 0.7985554071948019 0.9200534322340183 1.2780485313966354 0.7616262013519416 1.0479977746912446 1.0 18.73221450247393 -5.261840597231522 24.999971818543948 0.8963166539861674 1.4437369861949385 0.6019145141351507 0.1749698436422375 23.257634485652055 1449308.6955372384 0.04807596004216865 0.11110460479009868 5.4721677562955715e-06 5.261840597231522 0.5474203322087711 SLDSEPSVPSAAKPPS(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLDSEPSVPSAAKPPSPEK 19 1 Q7Z3K3-5;Q7Z3K3-7;Q7Z3K3-2;Q7Z3K3-3;Q7Z3K3-6;Q7Z3K3 Q7Z3K3-5 POGZ Pogo transposable element with ZNF domain 1 SLDSEPSVPSAAKPPS(1)PEK;SLDSEPSVPSAAKPPS(1)PEK;SLDSEPSVPSAAKPPS(1)PEK 106.19 0.00010663 178850000.0 254731.0 285333.0 158790.0 237839.0 238797.0 179098.0 260953.0 188630.0 167458.0 170464.0 True False 297851.92713341693 313658.9745398963 162576.15581442826 224513.65191444228 192006.4420686082 169705.78559599008 236233.64270388693 183678.662370006 169906.75645058855 201367.7738077182 1.4791439638093702 1.557642360586469 0.8073593541818106 1.1149433083012856 0.9535112716295462 0.8427653660115373 1.1731452269490819 0.912155201881493 0.8437633948956942 1.0 17.619473292399945 -5.254112949373672 24.982553376516485 0.9621232031755973 1.5183932363586734 0.7990904004054826 0.11277328394777068 222.05395108519667 757182.0231324285 0.028079741331325715 0.07114942004235215 5.570408573873127e-06 5.254112949373672 0.5562700331830761 SLDSEPSVPSAAKPPS(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 4 SLDSEPSVPSAAKPPSPEK 19 1 Q7Z3K3-5;Q7Z3K3-7;Q7Z3K3-2;Q7Z3K3-3;Q7Z3K3-6;Q7Z3K3 Q7Z3K3-5 POGZ Pogo transposable element with ZNF domain 1 SLDSEPSVPS(0.001)AAKPPS(0.999)PEK;SLDSEPS(0.001)VPS(0.059)AAKPPS(0.94)PEK;SLDSEPSVPS(0.001)AAKPPS(0.999)PEK;SLDSEPSVPSAAKPPS(1)PEK 96.805 0.00030131 270800000.0 326026.0 389938.0 298933.0 348838.0 378341.0 345758.0 368823.0 380792.0 258683.0 287608.0 True False 321376.8094541535 389035.1225187196 274355.88265475 374492.7102094543 356087.7262270249 330970.7363412648 387918.85027520085 398484.98646954086 229547.39648724734 337320.6595864291 0.9527338463294142 1.1533095037691876 0.8133385099837146 1.1101979661388066 1.0556356870154504 0.9811754096148466 1.1500002719987787 1.181323986968667 0.6805020385311804 1.0 18.36376115499307 -8.256913129621843 24.99985340591415 0.840251022009931 1.0485600942773385 0.30121604171292127 0.12760492140369098 423.94374415583644 2341602.9143567192 0.08885952230183447 0.031028899490210614 5.534608049375875e-09 8.256913129621843 0.20830907226740758 SLDSES(ph)ISPGDFHR ddPTM_PC-9_Lapatinib_30min_R1 1 SLDSESISPGDFHR 14 0 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 SLDS(0.002)ES(0.769)IS(0.229)PGDFHR 94.61 0.0019287 11587000.0 21806.0 19324.0 20535.0 18115.0 23462.0 18436.0 18329.0 20710.0 25505.0 15293.0 True False 21495.042441269365 19279.256465263017 18846.691567392314 19447.23752986851 22082.011288066748 17647.535256415038 19277.98593551422 21672.262205572057 22632.35832044335 17936.37467335839 1.1984050753130624 1.0748691871328526 1.0507525578948824 1.0842345727062819 1.231130130263505 0.9838964438353098 1.074798351762164 1.2082855426611225 1.2618134228685627 1.0 14.130600699611314 -7.757081429475072 24.999143708119163 1.176287116406574 1.0968900676272775 0.06275578675178795 0.09152641676120198 220.63254793521344 1265668.2163975202 0.04367599808784757 0.024083207934549187 1.749518626109817e-08 7.757081429475072 -0.07939704877929654 SLDSESIS(ph)PGDFHR ddPTM_PC-9_AZD4547_30min_R2 5 SLDSESISPGDFHR 14 0 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 SLDSES(0.008)IS(0.992)PGDFHR;SLDSES(0.002)IS(0.998)PGDFHR;SLDSES(0.006)IS(0.994)PGDFHR;SLDS(0.027)ES(0.039)IS(0.933)PGDFHR;SLDSESIS(1)PGDFHR 147.49 1.1107e-05 41031400.0 165252.4 160546.2 302396.0 421921.0 361168.0 304643.0 262887.0 425795.0 311155.0 316622.0 True False 217799.22573654974 212439.61949794463 298386.03145796363 324653.6320644687 311026.0574134759 285593.62505112786 286283.43372039986 359998.16654571204 327602.0180644772 305537.16015223676 0.7128403812748316 0.6952987957081704 0.9765948970308227 1.0625667657011244 1.017964745298098 0.9347263190795783 0.9369840106445856 1.1782467519379298 1.0722166099247843 1.0 18.220988329135757 -5.310447110215475 4.016911385810425 1.027416822541876 0.6992764119285636 0.7868573080271247 0.06662942633272628 0.09688953532521496 3.305677651930128 0.01940150517092073 0.04632297302521764 4.892748469772481e-06 5.310447110215475 -0.32814041061331245 SLDSESIS(ph)PGDFHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SLDSESISPGDFHR 14 0 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 SLDSES(0.01)IS(0.99)PGDFHR;SLDSES(0.003)IS(0.997)PGDFHR;SLDSES(0.003)IS(0.997)PGDFHR;SLDS(0.002)ES(0.137)IS(0.861)PGDFHR;SLDSES(0.003)IS(0.997)PGDFHR;SLDSES(0.006)IS(0.994)PGDFHR 136.36 3.074e-05 29581400.0 83823.8 106607.6 160733.0 171249.3 189301.1 165461.8 185503.0 196903.0 174948.0 133591.8 True False 98013.5137444838 117190.89798291618 164565.48430329698 161654.75691872186 152208.90836431662 156784.69192914845 167930.8129145827 191734.50488597402 177506.2835309012 157810.93582789332 0.6210818865644149 0.7426031495733803 1.0428015234810475 1.024357127537857 0.9645016523462848 0.9934970039093863 1.0641265894128273 1.214963360302719 1.1248034402665692 1.0 17.26783765772231 -4.386890354964 0.7261092728433207 1.0834135208992 2.999838000331699e-14 0.8029011921643092 0.07364370646184473 2.152200867870464 0.5777596395086789 0.03254976168512202 2.1733354056083227 4.1030767907052364e-05 4.386890354964 -1.08341352089917 SLDSESIS(ph)PGDFHR ddPTM_PC-9_Lapatinib_30min_R1 2 SLDSESISPGDFHR 14 0 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 SLDSES(0.025)IS(0.975)PGDFHR;SLDSES(0.043)IS(0.957)PGDFHR 108.77 0.00037067 14847800.0 93483.0 80428.0 90089.0 77014.0 86991.0 86858.0 96440.0 77334.0 108765.0 70747.0 True False 92149.91527731752 80241.77390748159 82682.23017359665 82677.86647117273 81874.36041088628 83143.28581588723 101433.19131545603 80927.21996164718 96514.74035377442 82975.52468554811 1.1105674308964908 0.9670535282732275 0.9964652888539969 0.9964126986180153 0.9867290471637883 1.0020218146372064 1.2224471216043145 0.9753143504465518 1.163171196802139 1.0 16.34039822658692 SLDSFRSQVLPQEGPVKES(ph)HS(ph)T(ph)T(ph)TEK ddPTM_PC-9_AZD4547_30min_R2 1 SLDSFRSQVLPQEGPVKESHSTTTEK 26 2 A0A1B0GUL6;E9PEZ5;Q9UPP5-2;Q9UPP5 A0A1B0GUL6 KIAA1107 Uncharacterized protein KIAA1107 4 S(0.001)LDS(0.004)FRS(0.001)QVLPQEGPVKES(0.799)HS(0.799)T(0.799)T(0.799)T(0.799)EK 52.483000000000004 0.026035000000000003 13476000.0 13182.0 12632.0 16900.0 22234.0 21564.0 17345.0 22627.0 26096.0 22391.0 22842.0 True False 17373.601797366922 16715.046967776492 16675.89495773616 17108.2948118757 18570.210821734505 16260.414408050763 24640.75916569283 22063.462826423278 23574.54254786752 22042.30853256369 0.7881933859922357 0.7583165321854972 0.7565403112428273 0.7761571246768986 0.8424803052865465 0.7376910809513813 1.117884686592168 1.0009597131728891 1.0695133185818637 1.0 14.427987707545183 -7.257474759598855 24.999936550583566 1.0471694102792823 0.7778013797354221 0.9136714265642398 0.04073671048313457 87.38874507433052 551054.5496475259 0.015274847329049606 0.01138410156103562 5.5274553157049666e-08 7.257474759598855 -0.26936803054386027 SLEAASEK ddPTM_PC-9_Lapatinib_30min_R1 1 SLEAASEK 8 0 A0A2R8YGX3;A0A2R8Y5V9;P67936;A0A2R8YH90;A0A2R8YEU4;A0A2R8YE05;K7ENT6;A0A2R8YHD2;P67936-2;A0A5F9UN72;K7EPB9 A0A2R8YGX3 TPM4 Tropomyosin alpha-4 chain 0 108.74 0.017458 11177000.0 61411.0 57479.0 56329.0 45457.0 65178.0 47173.0 60760.0 60820.0 56659.0 53224.0 False True 60535.26787860184 57345.91090699922 51697.84705622796 48800.05942010669 61344.35818487834 45155.5207556339 63905.85549903672 63645.91923432606 50277.466774279506 62423.69748347786 0.9697481936987816 0.9186561068763571 0.8281766242685514 0.7817553491287978 0.9827094622377152 0.7233714530861545 1.0237435152884231 1.0195794513961896 0.8054227609248366 1.0 15.929806193120129 -7.314444569295252 24.999966199765478 0.9638180236627186 0.8692969807665221 0.19454246453113044 0.09441213227841065 575.641547314542 271499.8360570151 0.03878761665695954 0.026150624077223922 4.847919845744866e-08 7.314444569295252 -0.09452104289619656 SLEATDSAFDNPDY(ph)WHSR ddPTM_PC-9_AZD4547_30min_R2 2 SLEATDSAFDNPDYWHSR 18 0 B3KWG5;F8VW56;F8VYK4;P21860-5;P21860-4;P21860 B3KWG5 ERBB3 Receptor tyrosine-protein kinase erbB-3 1 SLEATDSAFDNPDY(0.969)WHS(0.031)R;SLEATDSAFDNPDY(0.995)WHS(0.005)R 100.45 0.0010207 2632300.0 8744.9 16188.4 15986.8 17245.1 14523.3 12014.400000000001 14040.5 18066.699999999997 13837.4 10542.5 True False 11525.596294780307 21420.98371858399 15774.804586410437 13269.50862913904 12506.990485406088 11263.137668727879 15290.077299947401 15274.906646464655 14568.816714388015 10173.41028388726 1.132913740148144 2.105585356417871 1.550591605589201 1.3043323977757397 1.2293803293488295 1.1071152498947712 1.5029451160702685 1.5014539097727329 1.4320484781255935 1.0 13.312515753428261 -5.655304044387739 4.621980525724545 1.3159693612400503 1.6644484663495478 0.20350418485280986 0.2671502154649257 0.29689646034899525 10.686289813429438 0.0715317627228171 0.12690942377586273 2.211545890609118e-06 5.655304044387739 0.34847910510949753 SLEATDSAFDNPDY(ph)WHSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLEATDSAFDNPDYWHSR 18 0 B3KWG5;F8VW56;F8VYK4;P21860-5;P21860-4;P21860 B3KWG5 ERBB3 Receptor tyrosine-protein kinase erbB-3 1 SLEATDSAFDNPDY(0.996)WHS(0.004)R 113.33 0.004307899999999999 0.0 3682.0 4807.6 4469.1 6288.3 9356.6 7976.5 9023.2 4771.2 7447.9 6547.9 True False 4305.289877185113 5284.866755678483 4575.660293156134 5935.9869379436705 7523.241396915102 7558.198298174265 8168.457173689187 4645.961055504269 7556.811447457519 7734.982436852123 0.5565998258345395 0.683242243770271 0.5915540636984656 0.7674208682960393 0.9726255306116516 0.9771448558388965 1.0560408172062343 0.6006427413938665 0.9769655599286514 1.0 12.91718230053871 -5.994419046178251 3.4049755912559196 0.9182408853422822 0.6189522036696783 0.5845329861809774 0.1209080124729412 0.1842024127058355 4.520153066843192 0.036940031594191014 0.05417106286750403 1.0129335451334887e-06 5.994419046178251 -0.2992886816726039 SLEDDIR ddPTM_PC-9_AZD4547_30min_R2 1 SLEDDIR 7 0 P09525-2;P09525;Q6P452;B4E1S2 P09525-2 ANXA4 Annexin A4;Annexin 0 94.40700000000001 0.023150999999999998 0.0 33036.0 29778.0 44729.0 54536.0 45969.0 44649.0 37827.0 51246.0 41768.0 43571.0 False True 43540.760808512634 39403.15615947183 44135.864234590576 41963.567772800816 39586.99783269863 41857.09097175314 41193.52971939111 43327.1082159292 43975.77120893799 42045.59255198025 1.035560641812431 0.9371530704617466 1.0497144065701098 0.9980491467904031 0.9415255067164984 0.995516733888479 0.9797347883363579 1.0304791914245146 1.0459068011604664 1.0 15.359666956803682 -7.768911505733244 24.851332738614023 1.028644763669847 0.9897585283655479 0.1680885793756346 0.03480019046129037 256.94121514209286 854535.5714158583 0.017993052583257046 0.008914010593156512 1.7025053850492874e-08 7.768911505733244 -0.03888623530429913 SLEDDIR ddPTM_PC-9_Lapatinib_30min_R1 1 SLEDDIR 7 0 P09525-2;P09525;Q6P452;B4E1S2 P09525-2 ANXA4 Annexin A4;Annexin 0 127.12 0.02084 6840200.0 72824.0 85454.0 85050.0 68093.0 76568.0 85012.0 75479.0 71328.0 80476.0 73697.0 False True 71785.51640571382 85256.1365132779 78057.51730249409 73100.78637158925 72064.42077848 81376.23493265104 79386.93329841668 74642.15927566618 71411.9454301508 86435.42825492016 0.8305103341884301 0.9863563845815141 0.9030731828190002 0.8457271265666244 0.8337370709374357 0.9414685225212484 0.9184536352881174 0.8635597784687014 0.8261883682642114 1.0 16.399335146698512 -7.7692509302336905 24.870935745699718 0.8836555781091854 0.8957054256447997 0.0 0.062220797778033715 1594.9953644233212 5078170.0031631235 0.032943775166122694 0.016287859812346803 1.7011753053368483e-08 7.7692509302336905 0.012049847535614333 SLEEAIQFINQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLEEAIQFINQR 12 0 P30838;A8MYB8;I3L3I9;C9JMC5;E9PNN6 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 0 ; 199.68 2.9133e-05 6553100.0 16375.8 18085.0 19922.1 25103.0 23034.0 23135.0 19826.4 17716.9 16185.699999999999 12742.9 False True 19147.89950320695 19880.359280398803 20397.118418984974 23696.56029502406 18520.653050952522 21921.75987316012 17948.299861294363 17251.850147607223 16422.385242163986 15053.086897259109 1.2720247769707242 1.3206832203977148 1.3550123345596918 1.5741993955630968 1.2303558185347878 1.4562966402028592 1.192333505001052 1.1460672661597715 1.0909646210276114 1.0 13.87777174658143 -7.696320700467676 1.4134746008714625 1.0425328127374878 1.3708765536574103 0.6520682436953759 0.09594484542317443 0.2713913312822122 1.014480104981687 0.07475053333873753 0.030459576530841453 2.0122377839939127e-08 7.696320700467676 0.3283437409199226 SLEEAIQFINQR ddPTM_PC-9_Lapatinib_30min_R1 2 SLEEAIQFINQR 12 0 P30838;A8MYB8;I3L3I9;C9JMC5;E9PNN6 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 0 ; 195.83 6.234e-05 9948000.0 27985.0 28164.0 29392.0 21992.4 26635.0 27249.0 21128.7 21634.9 26181.0 19859.7 False True 27585.92876817952 28098.787988391014 26975.50321640103 23609.794460495723 25068.381666424764 26083.62379052146 22222.640702476907 22640.13643608551 23232.22008184776 23292.42268361315 1.1843305929523154 1.206348878777615 1.1581235487100716 1.0136255374201952 1.076246211351001 1.1198330094220725 0.9540716740517996 0.9719957749184013 0.9974153568058104 1.0 14.50757308401268 -5.619149206993505 0.4883022088215355 0.9782790084602754 1.275121632922578 0.7273903049595837 0.04620366744600744 1.2042257230784372 0.3945245321296609 0.03700936957612538 0.18937934524072145 2.403536894680761e-06 5.619149206993505 0.2968426244623027 SLEEIYLFSLPIK ddPTM_PC-9_Lapatinib_30min_R1 2 SLEEIYLFSLPIK 13 0 H0YEN5;P15880;E9PQD7;E9PMM9;E9PPT0;H3BNG3;H0YE27 H0YEN5 RPS2 40S ribosomal protein S2 0 ; 203.83 4.7495e-09 7626300.0 55819.0 51131.0 62825.0 53185.0 64645.0 51119.0 63863.0 59203.0 56894.0 58518.0 False True 55023.01082404905 51012.60931097925 57659.77101151314 57096.402319958994 60842.70819696 48932.75953420921 67169.51365594113 61953.78751117736 50485.9985996198 68632.75832966634 0.8017018718635048 0.7432691116091887 0.8401202634834196 0.831911811641107 0.8864966187824174 0.7129650727305556 0.9786800835441183 0.9026853796782053 0.7355962346306771 1.0 16.066609716870662 -14.522878744770283 0.11001207041346513 1.5106193674546013 0.7375219377824201 0.30226286765336596 0.07868698608147233 212.19044146717917 1.5461295277807972 24.800081576204704 0.9804847949337165 3.0000000035233307e-15 14.522878744770283 -0.7730974296721812 SLENETLNKEEDCHS(ph)PTSKPPKPDQPLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLENETLNKEEDCHSPTSKPPKPDQPLK 28 3 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 S(0.002)LENET(0.009)LNKEEDCHS(0.33)PT(0.33)S(0.33)KPPKPDQPLK 45.54600000000001 0.042719 13914000.0 31882.0 30176.0 31943.0 41691.0 41905.0 44842.0 49561.0 43233.0 34854.0 35779.0 True False 37278.99290179682 33171.673853763576 32704.642264502116 39355.18843404567 33694.01606755949 42490.40658017056 44866.22328943277 42098.1795591499 35363.67381271021 42265.44947359183 0.8820205005767031 0.7848413838468653 0.7737914223516429 0.9311432606113762 0.7971999940190411 1.0053224822965454 1.0615342755899462 0.9960423959398222 0.8367040751525908 1.0 15.367191171944588 -6.764981728060131 24.99985308051072 0.9847741662146852 0.8331536456587996 0.5273287831755757 0.06909302710196888 74.72926415811342 527391.7362272241 0.024450203317133632 0.022418285196668417 1.7179806657160059e-07 6.764981728060131 -0.1516205205558856 SLENETLNKEEDCHS(ph)PTSKPPKPDQPLK ddPTM_PC-9_Lapatinib_30min_R1 1 SLENETLNKEEDCHSPTSKPPKPDQPLK 28 3 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 SLENET(0.013)LNKEEDCHS(0.329)PT(0.329)S(0.329)KPPKPDQPLK 52.79 0.010971999999999999 47524000.0 161620.0 161090.0 187440.0 158040.0 216890.0 202410.0 173590.0 178400.0 191980.0 158320.0 True False 159315.26916252167 160717.00600233994 172029.4067393236 169662.78880598518 204132.95662214642 193753.3961407554 182577.64081760676 186689.11528121933 170357.19076097672 185685.4010518605 0.857984894127601 0.8655338819956714 0.9264562844726663 0.9137109748256389 1.099348443473667 1.0434498083489157 0.9832633033256838 1.0054054558068273 0.9174506439167895 1.0 17.502500866672868 -6.071448999141093 7.455341586082574 1.0091100258045689 0.8876676821402457 0.6112110038486 0.046232951249362546 0.20193922689980218 18.700535511528486 0.014548086101890064 0.018907177149899125 8.483029960624682e-07 6.071448999141093 -0.12144234366432316 SLENPT(ph)PPFTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLENPTPPFTPK 12 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 SLENPT(1)PPFTPK;SLENPT(1)PPFTPK;S(0.086)LENPT(0.913)PPFT(0.001)PK 154.47 0.00065737 9082400.0 82449.0 80713.0 79049.0 95491.0 114647.0 83874.9 92455.0 92205.0 78115.0 69353.0 True False 96405.98725802168 88725.6532263662 80933.82795500204 90140.94885599907 92182.74335037578 79476.35259067717 83696.99308376544 89784.71644927289 79257.28409593897 81926.14990195421 1.1767425586750546 1.0829955189222165 0.9878876042858142 1.1002707800119496 1.125193158236976 0.9700974925074735 1.0216151153682982 1.0959225663200758 0.9674235172871027 1.0 16.322036396889708 -4.844612350919131 3.3629873297543877 1.0396293050998375 1.1857052388466351 0.3931977331201496 0.053817052028131675 0.29314677910396086 5.471630184977517 0.013665581419521908 0.10097902087769414 1.4301699514945018e-05 4.844612350919131 0.14607593374679761 SLENPT(ph)PPFTPK ddPTM_PC-9_Lapatinib_30min_R1 1 SLENPTPPFTPK 12 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 S(0.005)LENPT(0.979)PPFT(0.016)PK 76.868 0.039615 0.0 33698.0 34376.0 31664.0 28980.0 27851.0 35716.0 26504.0 34506.0 29362.0 22752.0 True False 33217.46034054362 34296.40448405513 29060.70814657463 31111.285874446006 26212.858937172765 34188.509938062474 27876.24743493201 36109.2747303462 26054.94236443275 26684.65288486566 1.244815155882469 1.285248289795312 1.089042014972455 1.1658868492192729 0.9823196520588628 1.2812049714707987 1.044654676798969 1.353185101794064 0.976401772091626 1.0 14.70372262435741 -7.350137127428521 0.020387811491348263 1.3419965248556406e-06 2.274009625045467 0.18874485460871004 0.12117748638292443 679.8894405737992 9.060166184300451 489.804329809669 517.7463418754076 4.465425751550113e-08 7.350137127428521 2.274008283048942 SLENPTPPFT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLENPTPPFTPK 12 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 SLENPT(0.131)PPFT(0.869)PK;SLENPT(0.008)PPFT(0.992)PK 108.32 0.0035347 8488500.0 85728.0 92019.0 72741.0 100485.0 115887.0 92119.0 118421.0 97727.0 83145.0 81875.0 True False 100240.05719481941 101154.03818761512 74475.42131177874 94855.1512267654 93179.77425179 87288.1174737687 107203.30558620507 95161.76980031563 84360.83833011388 96718.2893778568 1.0364126354965177 1.0458625647567943 0.770024178372509 0.9807364443366805 0.9634142089481897 0.9024985660442513 1.1084077921124684 0.9839066676266348 0.8722325309180655 1.0 16.5615011079257 SLENPTPPFT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 SLENPTPPFTPK 12 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 SLENPTPPFT(1)PK 92.26899999999999 0.014555000000000002 6421300.0 51374.0 39395.0 35477.0 32177.0 46028.0 31304.0 37160.0 36111.0 39403.0 27884.0 True False 50641.397339162264 39303.78329792157 32560.218005180268 34543.40391932537 43320.723534529745 29965.200893188143 39083.96297472357 37788.84888968677 34965.019208015234 32703.712246905467 1.5484907938533528 1.2018141243779021 0.9956122950005843 1.0562532980516297 1.324642389447054 0.9162629816137631 1.195092553397262 1.1554911138035249 1.0691452684037035 1.0 14.997166787022845 -4.795469947616731 3.3510446019870628 1.0991705789982043 1.6006331747651306 0.6110780853935782 0.10983773093512215 0.1960207940578234 3.539069019917616 0.026841404948272567 0.2506404101663021 1.601511466172367e-05 4.795469947616731 0.5014625957669263 SLEPEES(ph)PGKR ddPTM_PC-9_Lapatinib_30min_R1 1 SLEPEESPGKR 11 1 Q5JWZ0;Q5JXL1;Q9BVI0 Q5JWZ0 PHF20 PHD finger protein 20 1 SLEPEES(1)PGKR 61.423 0.027226 8758800.0 48994.0 42090.0 36708.0 38306.0 38860.0 43937.0 27371.0 32804.0 37982.0 36449.0 True False 48295.336575600806 41992.54319100191 33690.00993697771 41123.151025069994 36574.33120169952 42057.91693214947 28788.136452668434 34328.19359688972 33704.067191808615 42749.161084760344 1.1297376451398393 0.9823009884975693 0.7880858730813285 0.9619639305560547 0.8555567003802071 0.9838302288262378 0.6734199156701375 0.8030144387822241 0.788414704208635 1.0 15.383608488185846 -1.5228793105185292 0.7659441128040237 0.840876841726123 59.463734417475315 0.41481928673348056 0.09915230687782023 387.61978208026346 1.5654607175712936 0.036339771469275896 39284.01189548622 0.029999960954754386 1.5228793105185292 58.622857575749194 SLEPEPQQS(ph)LEDGSPAKGEPSQAWR ddPTM_PC-9_AZD4547_30min_R2 1 SLEPEPQQSLEDGSPAKGEPSQAWR 25 1 Q8IV36-3;Q8IV36-2;Q8IV36 Q8IV36-3 HID1 Protein HID1 1 S(0.001)LEPEPQQS(0.616)LEDGS(0.384)PAKGEPSQAWR 80.314 0.00037185 0.0 11405.0 9094.3 14157.0 14337.0 13930.0 12927.0 11502.0 14150.0 10463.0 11041.0 True False 15031.552761263074 12033.854626270562 13969.268929980528 11031.826154441931 11996.059949302617 12118.672646461357 12525.655717673528 11963.442634652425 11016.052819362143 10654.457950618855 1.4108228528312865 1.1294666215817752 1.311119626613115 1.035418808312173 1.1259193104803455 1.1374274226458845 1.1756258061862253 1.1228579332801758 1.03393836368018 1.0 13.379169576907858 -1.5228787452803376 0.5705161855345084 1.0981488411938765 15.201102086186294 0.5518118532956016 0.080784053169174 118.36023178843966 1.0142244460841334 0.0369868445818914 2061.0458040205995 0.029999999999999995 1.5228787452803376 14.102953244992417 SLEPEPQQSLEDGS(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLEPEPQQSLEDGSPAK 17 0 Q8IV36-3;Q8IV36-2;Q8IV36 Q8IV36-3 HID1 Protein HID1 1 SLEPEPQQS(0.113)LEDGS(0.887)PAK;S(0.028)LEPEPQQS(0.289)LEDGS(0.683)PAK 127.01 4.9513000000000005e-05 0.0 21030.4 31139.0 25838.0 22623.0 24468.3 21058.9 25293.0 17662.0 16130.3 16693.1 True False 24590.43135066644 34230.27412951832 26454.07591116068 21355.50665475561 19673.912262161215 19954.53421192529 22897.063934537717 17198.391214435876 16366.175121970493 19719.426887493097 1.247015518806114 1.7358655667233729 1.3415235677026183 1.0829679166943835 0.9976918890395974 1.0119226246165047 1.1611424644932258 0.872154718925621 0.8299518649981973 1.0 14.26733000233086 -5.72555008734649 2.7440853977279174 0.9871892647933028 1.5013315243277545 0.6942412649789531 0.13917675128831034 0.1397168556873195 2.139905472254985 0.039862713128397335 0.07329970269499166 1.8812647267355582e-06 5.72555008734649 0.5141422595344517 SLEPEPQQSLEDGS(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 2 SLEPEPQQSLEDGSPAK 17 0 Q8IV36-3;Q8IV36-2;Q8IV36 Q8IV36-3 HID1 Protein HID1 1 SLEPEPQQSLEDGS(1)PAK;SLEPEPQQS(0.2)LEDGS(0.8)PAK 154.48 1.2928e-12 3271800.0 27439.0 33625.0 25224.0 22322.0 23848.0 31774.0 28494.0 31138.0 29605.0 24181.0 True False 27047.71482830368 33547.143378413864 23150.18008745576 23963.634344009108 22445.307526971963 30415.100088811643 29969.27989778725 32584.785154857676 26270.573145529306 28360.653630842815 0.9537056225985114 1.1828762416790928 0.8162780868449183 0.8449605801027147 0.7914241970277516 1.072440024997681 1.0567203523544684 1.148943376940404 0.9263035149852646 1.0 14.791603162448064 -6.806218831139437 24.999740671494262 1.0511804964101756 0.9228800760975304 0.2204188409534248 0.11468143853534513 215.9784184689963 120576.2209540761 0.042981616787230816 0.037906389946768336 1.5623602063990112e-07 6.806218831139437 -0.1283004203126452 SLEPEPQQSLEDGS(ph)PAKGEPSQAWR ddPTM_PC-9_AZD4547_30min_R2 3 SLEPEPQQSLEDGSPAKGEPSQAWR 25 1 Q8IV36-3;Q8IV36-2;Q8IV36 Q8IV36-3 HID1 Protein HID1 1 SLEPEPQQS(0.135)LEDGS(0.851)PAKGEPS(0.013)QAWR;SLEPEPQQS(0.016)LEDGS(0.983)PAKGEPS(0.001)QAWR;SLEPEPQQS(0.001)LEDGS(0.949)PAKGEPS(0.05)QAWR 82.26700000000001 1.9726e-05 56257700.0 98101.0 82961.0 98525.0 112225.0 108206.0 99546.0 94001.0 101391.0 91346.0 98442.0 True False 129295.07737243909 109776.5208592231 97218.49412490851 86353.26010896607 93183.46467151758 93321.37288347207 102366.90689593373 85723.35068339539 96174.36307344487 94995.575543413 1.3610642035991583 1.1555961446757614 1.0234002327874696 0.9090240215398518 0.9809242602981306 0.9823759932990161 1.0775965755284258 0.9023930871835162 1.0124088677108247 1.0 16.53557270046437 -4.897943274168781 1.7777177640015116 0.980067977220602 1.4351184993729298 0.8595485698537574 0.047904968553197855 0.2330411426258458 0.9110786902122779 0.013341115529235307 0.16758741239095626 1.2649015531304111e-05 4.897943274168781 0.4550505221523278 SLEPEPQQSLEDGS(ph)PAKGEPSQAWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLEPEPQQSLEDGSPAKGEPSQAWR 25 1 Q8IV36-3;Q8IV36-2;Q8IV36 Q8IV36-3 HID1 Protein HID1 1 SLEPEPQQS(0.031)LEDGS(0.969)PAKGEPS(0.001)QAWR;SLEPEPQQSLEDGS(0.998)PAKGEPS(0.002)QAWR 92.79799999999999 1.831e-06 18789000.0 50023.8 46512.0 47208.0 63014.0 63962.0 50387.0 55347.0 55968.0 47258.0 43322.0 True False 58491.84132491382 51129.40397290069 48333.617757336986 59483.52987414438 51429.10525505885 47744.61701875595 50104.131482420395 54498.8993029978 47949.058846647684 51175.93566323666 1.1429559727020817 0.9990907505699129 0.9444598741759496 1.1623339974783433 1.0049470437333705 0.932950544039673 0.979056481001749 1.06493215212767 0.9369454261115332 1.0 15.643177954216236 -6.507670326676456 24.943160810973062 0.9846411069899669 1.0535845905903627 0.23020821095074817 0.06808229403858505 1196.929165739511 1963072.3225691486 0.021612575588887427 0.02371256193097214 3.1069171567478034e-07 6.507670326676456 0.06894348360039582 SLEPEPQQSLEDGS(ph)PAKGEPSQAWR ddPTM_PC-9_Lapatinib_30min_R1 3 SLEPEPQQSLEDGSPAKGEPSQAWR 25 1 Q8IV36-3;Q8IV36-2;Q8IV36 Q8IV36-3 HID1 Protein HID1 1 SLEPEPQQSLEDGS(1)PAKGEPSQAWR;SLEPEPQQS(0.001)LEDGS(0.998)PAKGEPS(0.001)QAWR;SLEPEPQQS(0.03)LEDGS(0.657)PAKGEPS(0.313)QAWR 132.78 1.2818e-07 48505400.0 108243.0 98163.0 93551.0 88389.0 80693.0 77930.0 76330.0 72894.0 91059.0 64779.0 True False 106699.43497066488 97935.70960461657 85859.59789730328 94889.42191706016 75946.79638854194 74597.11556370273 80281.99391444163 76280.92135263007 80802.97652622027 75975.96383740816 1.4043840917767925 1.2890354351305529 1.1300889592009193 1.2489400216116722 0.9996160963626782 0.9818515198220292 1.0566762152073328 1.00401386833176 1.0635334182682057 1.0 16.213255451562617 -4.872331599375851 0.5982635549871905 1.0100985493279107 1.6314279187164105 0.8321738022592116 0.05717082778711389 1.32322768013888 0.3874063400589027 0.03033240794086346 0.56122318046734 1.3417401033539166e-05 4.872331599375851 0.6213293693884998 SLES(ph)LIYMSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLESLIYMSTR 11 0 O95171-2;O95171;O95171-3;F2Z2X8 O95171-2 SCEL Sciellin 1 S(0.06)LES(0.94)LIYMSTR;S(0.462)LES(0.538)LIYMSTR 87.568 0.009071899999999999 10086600.0 27921.0 30250.0 36740.0 45667.0 52671.0 47969.0 46707.0 40742.0 39847.0 33505.0 True False 32647.473835112854 33253.020084714626 37616.02093722591 43108.4260444116 42350.49565193714 45453.42119540171 42282.57483060346 39672.56566971727 40429.68699188222 39579.191274565914 0.8248646014172738 0.84016421290759 0.9503989274636453 1.0891689460091019 1.0700192269757696 1.1484171285887452 1.0683031529695448 1.0023591789560227 1.0214884561793167 1.0 15.272454513509073 -5.472746361529774 2.623469837762588 1.0619733315338427 0.8293707240253716 0.8161275357517384 0.04259449742641869 0.11755118341234538 1.581672140431977 0.013025114492878298 0.03115405853272593 3.3670815766287835e-06 5.472746361529774 -0.23260260750847106 SLESLADGGS(ph)ASPIKDQPVMAVK ddPTM_PC-9_AZD4547_30min_R2 1 SLESLADGGSASPIKDQPVMAVK 23 1 A0A3B3ITU7;Q9HB96 A0A3B3ITU7 FANCE Fanconi anemia group E protein 1 SLES(0.001)LADGGS(0.54)AS(0.459)PIKDQPVMAVK 67.928 0.00065657 4942800.0 15462.0 11975.0 7819.7 14257.0 16329.0 12354.0 12633.0 14707.0 14025.0 17048.0 True False 20378.594370420848 15845.684566111739 7716.005668698781 10970.26891845425 14062.000209056889 11581.502427042895 13757.3125266362 12434.371083239088 14766.332867395015 16451.154709007347 1.2387333734855186 0.9631958878507111 0.4690251721038225 0.6668388397349276 0.8547728386116054 0.7039932838697203 0.836252091113324 0.7558357637005877 0.8975864082847718 1.0 14.005901230044469 -4.942742934103375 4.294979957703877 0.7601976237491175 1.2141700871823953 0.5179423782169289 0.13824903156823992 0.1597928870503453 5.911475417343476 0.034669537047244674 0.16127803119331494 1.1409249195611807e-05 4.942742934103375 0.4539724634332778 SLESLADGGS(ph)ASPIKDQPVMAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLESLADGGSASPIKDQPVMAVK 23 1 A0A3B3ITU7;Q9HB96 A0A3B3ITU7 FANCE Fanconi anemia group E protein 1 SLES(0.012)LADGGS(0.6)AS(0.388)PIKDQPVMAVK 94.45 1.5805999999999997e-05 9491300.0 51215.0 50027.0 40558.0 63238.0 58830.0 59265.0 60798.0 62951.0 41400.0 45588.0 True False 59884.68795764138 54993.34994307496 41525.056537071534 59694.97988036218 47302.6838146886 56157.039069930215 55038.77330059796 61298.602952097855 42005.396678894875 53852.74352559058 1.1120081176399945 1.0211800985950208 0.7710852561734207 1.1084853987428773 0.8783709188782662 1.0427888236231575 1.0220235720106587 1.1382633258595087 0.7800047672396505 1.0 15.716732224224977 SLESLADGGS(ph)ASPIKDQPVMAVK ddPTM_PC-9_Lapatinib_30min_R1 1 SLESLADGGSASPIKDQPVMAVK 23 1 A0A3B3ITU7;Q9HB96 A0A3B3ITU7 FANCE Fanconi anemia group E protein 1 SLESLADGGS(0.968)AS(0.032)PIKDQPVMAVK 109.13 6.3657e-07 7157000.0 30204.0 27204.0 30228.0 24656.0 26331.0 22321.0 24454.0 20777.0 24864.0 20362.0 True False 29773.28542126478 27141.010809408785 27742.770523454354 26469.284490004873 24782.26234873777 21366.38286279236 25720.108465659054 21742.3752701676 22063.55449047259 23881.54456934045 1.2467068591320618 1.1364847332468142 1.1616824214574049 1.1083573096853463 1.0377160604826907 0.8946817824431215 1.0769868084110013 0.910425839796009 0.9238746860116481 1.0 14.5436085273107 -6.155855282528265 1.2667314503009053 0.9589780867866562 1.1914402068583052 0.7511463704499481 0.0557605007040295 0.22286083569748563 0.7273713060240857 0.02129173536073133 0.03395453709962847 6.9846511084607e-07 6.155855282528265 0.23246212007164901 SLESLADGGSAS(ph)PIKDQPVMAVK ddPTM_PC-9_AZD4547_30min_R2 2 SLESLADGGSASPIKDQPVMAVK 23 1 A0A3B3ITU7;Q9HB96 A0A3B3ITU7 FANCE Fanconi anemia group E protein 1 SLESLADGGS(0.176)AS(0.824)PIKDQPVMAVK;SLES(0.001)LADGGS(0.079)AS(0.92)PIKDQPVMAVK 105.79 1.089e-06 15307900.0 63467.0 50806.0 65394.0 79469.0 71973.0 73038.0 57881.0 73881.0 59442.0 77680.0 True False 83648.18580439131 67228.04593451975 64526.83283231946 61148.649833810814 61980.791294411894 68470.92231393562 63032.296869645405 62464.38906648456 62583.98276675185 74960.44684395177 1.115897641038949 0.8968469208097322 0.8608117420464103 0.815745535256833 0.826846609164962 0.9134273499793076 0.8408740812453042 0.8332979817545544 0.8348934058122077 1.0 16.19384193256832 -4.744430886008944 3.063891329687486 0.8579443659510018 1.1703804427770554 0.6674058615888452 0.05241253992493872 0.23455978189553955 2.9857012062513397 0.012548448589214495 0.18872249158118048 1.8012297608614557e-05 4.744430886008944 0.3124360768260537 SLESLADGGSAS(ph)PIKDQPVMAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLESLADGGSASPIKDQPVMAVK 23 1 A0A3B3ITU7;Q9HB96 A0A3B3ITU7 FANCE Fanconi anemia group E protein 1 S(0.001)LES(0.002)LADGGS(0.453)AS(0.545)PIKDQPVMAVK 54.058 0.016941 10530000.0 50352.0 34920.0 37744.0 45500.0 50669.0 46806.0 51141.0 53112.0 47369.0 39072.0 True False 58875.59910266838 38386.62682175983 38643.96010491711 42950.7825129903 40740.77318045993 44351.410962746166 46296.55425122339 51717.86627681562 48061.682011656325 46155.44430621819 1.2755938110368594 0.8316814494750359 0.8372568108874404 0.9305680653409689 0.882686187791095 0.9609139643093203 1.0030572762785903 1.1205149696684438 1.0413003868577497 1.0 15.494213211826201 -7.398938697310605 2.9693746530011325 1.0606982152397983 0.9374412815499857 0.11194060293174235 0.12132900542811961 0.49629881398664166 8.370856998004525 0.057662671310711816 0.03564670836403717 3.990812305614726e-08 7.398938697310605 -0.12325693368981261 SLESLADGGSAS(ph)PIKDQPVMAVK ddPTM_PC-9_Lapatinib_30min_R1 1 SLESLADGGSASPIKDQPVMAVK 23 1 A0A3B3ITU7;Q9HB96 A0A3B3ITU7 FANCE Fanconi anemia group E protein 1 SLES(0.001)LADGGS(0.445)AS(0.554)PIKDQPVMAVK 76.161 0.00016911 3940700.0 45337.0 42853.0 37373.0 36200.0 42345.0 38732.0 34470.0 36942.0 38542.0 38272.0 True False 44690.48606621244 42753.77651138045 34300.336203951934 38862.26875965998 39854.35035347316 37075.522648701866 36254.68793699464 38658.4601834014 34200.994094747206 44887.26420576555 0.9956161699084385 0.9524700885176455 0.7641440575820664 0.8657749463525628 0.8878765738713491 0.825969755669353 0.8076831720196016 0.8612344919527511 0.761930910691462 1.0 15.454018548936098 -5.087458368775651 5.943777614112988 0.8421136871490306 0.9858061660525566 0.38646585732620575 0.0648519222835578 0.18346183031265192 9.783631309093513 0.015382034312085032 0.042923891667833385 8.176014089977089e-06 5.087458368775651 0.143692478903526 SLESVLSLGPRPTGGGS(ph)SPPEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLESVLSLGPRPTGGGSSPPEIR 23 1 Q13470-2;Q13470 Q13470-2 TNK1 Non-receptor tyrosine-protein kinase TNK1 1 SLESVLSLGPRPT(0.034)GGGS(0.482)S(0.482)PPEIR 44.106 0.031025 4503500.0 14255.0 9979.5 10275.0 9196.2 10736.0 10470.0 9760.7 11331.0 9609.5 7699.7 True False 16668.089950916306 10970.19880778213 10519.994968154491 8680.966728482672 8632.35786902085 9920.934768618392 8836.095834651573 11033.573256186888 9750.020758112081 9095.594659208338 1.832545377782596 1.2061002297058117 1.1566033186740678 0.9544144229969727 0.9490702029340645 1.0907406431721849 0.9714698341032546 1.21306782784307 1.07194978705886 1.0 13.15095224731572 -4.458629187438373 1.5672339614746909 1.0455098309169752 2.8337511642919258 0.8916996735810605 0.08163476316321489 0.8022751090230059 0.9768981909594437 0.02364316085257978 2.816521444950393 3.478330240836963e-05 4.458629187438373 1.7882413333749505 SLETENAGLR ddPTM_PC-9_Lapatinib_30min_R1 2 SLETENAGLR 10 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ; 163.16 0.0030737 12465000.0 81127.0 76727.0 90608.0 68898.0 88600.0 81939.0 67381.0 55763.0 66658.0 70800.0 False True 79970.1141031302 76549.34334559277 83158.5599969946 73964.98875699034 83388.72219430197 78434.65997913825 70869.6584822349 58353.952552839895 59150.27410014164 83037.68566493 0.9630580797473338 0.9218626787658956 1.0014556563215449 0.8907400075605502 1.004227436332805 0.9445670282242007 0.8534637967657842 0.7027405940515633 0.712330475331673 1.0 16.341478614595715 -7.416549134519571 3.407227213130178 0.7800697574218487 0.9543726611502849 0.38974049918626263 0.0833997967827883 0.2128437308281988 4.5983951242591345 0.03678716928010443 0.02301931760764789 3.83222381541981e-08 7.416549134519571 0.17430290372843615 SLETENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLETENR 7 0 P05783;F8VZY9;CON__P05784 P05783 KRT18 Keratin, type I cytoskeletal 18 0 129.68 0.020334 65545000.0 204580.0 243530.0 287750.0 251620.0 287060.0 230130.0 261640.0 253820.0 246600.0 173910.0 False True 239211.35336081803 267706.04896629945 294611.05129795225 237522.5471630462 230812.65367745244 218061.5776792887 236855.56509043838 247157.49394451964 250206.05847863457 205438.50632919744 1.1643939475372866 1.3030957718185687 1.4340595468790234 1.1561734526167011 1.1235121292577699 1.0614445245715711 1.152926826244043 1.203072872563 1.2179121769786478 1.0 17.648347092721828 -5.916607188866087 10.069320186281814 1.1351713896122944 1.3005738913622245 0.4580399035156575 0.08484654364169167 0.33798783230716084 38.13131543065193 0.024350033887482015 0.03615666383243427 1.2116935919711516e-06 5.916607188866087 0.1654025017499301 SLETENR ddPTM_PC-9_Lapatinib_30min_R1 3 SLETENR 7 0 P05783;F8VZY9;CON__P05784 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ;; 121.99 0.024794 213237000.0 851420.0 821140.0 797120.0 749880.0 851320.0 763410.0 790140.0 831970.0 808960.0 785800.0 False True 839278.594668693 819238.700780691 731583.870572181 805028.6767263477 801247.031359517 730760.7338956291 831049.583015287 870626.3634558091 717846.4060735482 921624.4829873177 0.9106513663225265 0.8889072674428554 0.7937982161681008 0.8734888141393109 0.86938557530762 0.7929050794386122 0.9017225544199468 0.9446649687883667 0.7788925091776521 1.0 19.813819516971407 -10.907225332181445 3.2599020670483783 1.001348238207192 0.8625918096427672 0.3806978345454448 0.05294215246203469 55078975.828821674 80393238.8818209 712942.069716662 0.012793575289377366 1.2381540079442695e-11 10.907225332181445 -0.13875642856442494 SLETENRR ddPTM_PC-9_AZD4547_30min_R2 4 SLETENRR 8 1 P05783;F8VZY9;CON__P05784 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ;;; 87.181 0.0075415000000000005 66022600.0 49523.3 41462.5 75280.0 107104.0 87972.0 74372.0 56042.0 74776.0 58578.0 61884.0 False True 65270.67925136866 54864.442281620686 74281.73801292175 82412.82754030461 75758.60630725401 69721.50708305271 61029.629432260444 63221.08738153846 61674.313490642846 59717.459996023645 1.0929915514778221 0.9187336883597176 1.243886428154645 1.3800457612529429 1.2686173576756026 1.1675229838592465 1.0219729612800708 1.0586700671084823 1.032768531929347 1.0 15.86586518318214 -7.228774444200719 5.773952302842617 1.032964804568769 1.183781162179394 0.2939338541609987 0.11395379314320143 0.295913248613116 30.18974537452831 0.051635608731756 0.038797920908355446 5.905076874566603e-08 7.228774444200719 0.15081635761062517 SLETENRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SLETENRR 8 1 P05783;F8VZY9;CON__P05784 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ;;;;; 110.31 0.0023818000000000003 125609300.0 164698.1 140171.9 209034.7 187434.0 221232.0 196364.5 185204.30000000002 163512.2 184052.6 142520.19999999998 False True 192578.23539424848 154087.23986818542 214018.8800165143 176932.6806492268 177883.1777271999 186066.79994005404 167660.4079409839 159220.17800549683 186744.02108168998 168357.98407071744 1.1438616140316666 0.9152357146511227 1.2712131307453607 1.050931333169846 1.0565770237096772 1.1051854829878347 0.9958565901487598 0.9457239517587573 1.1092079898227436 1.0 17.361172614409035 -7.263851910502374 24.849826821232398 1.0081741256483407 1.087407732795685 0.1469350384960062 0.09139922485663801 395.89476621847746 4077810.249737069 0.03559695822293838 0.02538606432242784 5.446883537367931e-08 7.263851910502374 0.07923360714734429 SLETENRR ddPTM_PC-9_Lapatinib_30min_R1 5 SLETENRR 8 1 P05783;F8VZY9;CON__P05784 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ;;;; 118.74 0.0022081999999999996 80670400.0 99363.8 74971.6 97060.8 72500.2 83282.5 72377.7 71461.3 72929.0 84955.9 64796.8 False True 97946.85399091098 74798.00786644133 89080.83568952284 77832.10656157724 78383.98708969484 69282.27449165932 75161.21645117362 76317.54758040379 75387.27191671246 75996.84054369113 1.2888279735076702 0.9842252300401807 1.1721649880735454 1.02414924100471 1.031411128790694 0.9116467736817091 0.9890044890479743 1.0042200048636005 0.9919790267250884 1.0 16.213651821438617 -1.5228787452819752 0.5828378067224085 0.9872173349774203 15.140151312384655 0.5930894005530283 0.0660089377499794 113.32385865804939 0.9316749261623567 0.03012729938221371 2031.5739757423066 0.029999999999886878 1.5228787452819752 14.152933977407233 SLFFS(ph)SK ddPTM_PC-9_Lapatinib_30min_R1 1 SLFFSSK 7 0 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 SLFFS(0.5)S(0.5)K 88.37 0.017315999999999998 3455400.0 70892.0 38636.0 27819.0 33326.0 30854.0 24807.0 29832.0 32029.0 31281.0 30020.0 True False 69881.06707999946 38546.54071578875 25531.829204445417 35776.90521227702 29039.228381297915 23746.062437941408 31376.554990902936 33517.18426761312 27757.804376466876 35208.91700086439 1.984754801696509 1.0947948417397337 0.7251523585294771 1.0161319421270096 0.8247691452873995 0.6744331964927643 0.8911536526423869 0.9519515827990467 0.7883742739313854 1.0 15.103653231246044 -4.773642562287199 3.028715676604839 0.856886694094733 2.1788339058548303 0.9084769887758077 0.10695694401320842 0.10098414527685697 1.3307182570968743 0.02677925109180342 0.3302884243106563 1.6840595236244942e-05 4.773642562287199 1.3219472117600972 SLFFSS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLFFSSK 7 0 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 SLFFS(0.263)S(0.737)K 118.18 0.007037699999999999 2796200.0 30226.0 52616.0 35897.0 45319.0 44343.0 35123.0 56656.0 38147.0 40554.0 52399.0 True False 35342.664809287715 57839.36875297009 36752.920620130615 42779.92335618038 35654.30746888892 33281.08804949226 51289.13352608107 37145.68167008749 41147.02552936964 61898.52390974422 0.5709775060358747 0.9344224239871555 0.5937608572656913 0.6911299438829729 0.5760122409522617 0.5376717560829115 0.8286002684145914 0.6001060982366968 0.6647497053300842 1.0 15.917617385540147 -10.481396038949457 6.8883752896617505 1.0000000221403182 0.6692351768870446 0.4128635096991582 0.1193106158292078 3.94303587425077e-08 5.9511677453948104e-09 0.11228785073488325 0.02723380243871362 3.300684099551804e-11 10.481396038949457 -0.33076484525327365 SLFS(ph)PQNTLAAPTGHPPTSGVEK ddPTM_PC-9_Lapatinib_30min_R1 1 SLFSPQNTLAAPTGHPPTSGVEK 23 0 Q5VT52-2;Q5VT52-3;Q5VT52 Q5VT52-2 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 S(0.008)LFS(0.793)PQNT(0.199)LAAPTGHPPTSGVEK 93.546 6.6223e-06 9321700.0 45130.0 28794.0 58814.0 33836.0 38665.0 43356.0 41869.0 32577.0 52516.0 31181.0 True False 44486.43792417158 28727.32926209808 53978.53994860539 36324.41231358712 36390.800718314764 41501.76494777231 44036.771953409596 34090.646348185466 46601.09506200362 36570.59430392914 1.2164537867352068 0.7855308290412886 1.4760093724483427 0.9932683076382063 0.9950836569917307 1.1348397732577555 1.204157952354586 0.9321873761434272 1.2742777619284356 1.0 15.158396451467029 SLGDDISSETSGDFRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLGDDISSETSGDFRK 16 1 P12429;D6RFG5;D6RA82 P12429 ANXA3 Annexin A3;Annexin 0 60.657 0.028223 3277700.0 9113.1 10778.0 13133.0 10789.0 9228.5 11715.0 16304.0 11720.0 12222.0 10180.0 False True 10655.767838070527 11847.968610679478 13446.140527179856 10184.527308409943 7420.24167234156 11100.644776921148 14759.567089261962 11412.36241836646 12400.723628247668 12025.553415164335 0.886093759696207 0.9852327125119313 1.1181307057539778 0.8469071615088548 0.6170395171156585 0.923088060373432 1.2273503413697378 0.9490093324083834 1.0311977503347363 1.0 13.553815667801855 -7.0251340829848 24.816010370674128 1.051580021247157 0.8925304906390391 0.24518973501640262 0.13490709483426436 1125.9276283183392 1111675.7186147287 0.05588592367492494 0.04349234997037242 9.437694542968615e-08 7.0251340829848 -0.159049530608118 SLGEKS(ph)PAASGAR ddPTM_PC-9_Lapatinib_30min_R1 1 SLGEKSPAASGAR 13 1 O75683 O75683 SURF6 Surfeit locus protein 6 1 SLGEKS(1)PAASGAR 150.37 0.00061422 6194700.0 13454.0 11863.0 15474.0 12311.0 11584.0 11397.0 11267.0 9139.4 13350.0 8989.8 True False 13262.143492838579 11835.53195236054 14201.787451367356 13216.392008292094 10902.651895020263 10909.576877704618 11850.350130145598 9564.04988902005 11846.382418267729 10543.674951844458 1.257829319796943 1.1225243576282755 1.346948527551389 1.2534900846862778 1.0340466625550713 1.0347034527839034 1.1239297668288377 0.9070888407221775 1.1235534547843191 1.0 13.364090179231262 -6.262637627990403 24.696054891679776 1.0367844222081604 1.2437035615460643 0.6377975978569093 0.07677778111818168 57.994781072355764 1195280.942934288 0.022705134239065228 0.027214684274750052 5.462134273300085e-07 6.262637627990403 0.20691913933790396 SLGEQDQMT(ph)LRPPEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLGEQDQMTLRPPEK 15 1 P48681 P48681 NES Nestin 1 S(0.041)LGEQDQMT(0.959)LRPPEK 88.134 0.026930000000000003 0.0 28283.0 37614.0 33472.0 27569.0 27200.0 20346.0 25351.0 19452.0 19776.0 17584.0 True False 33070.75328528697 41348.069337734065 34270.0994232669 26024.39830990394 21870.355256833758 19279.019942914034 22949.569754654083 18941.405611097653 20065.186587483702 20771.840005132595 1.5920955137876753 1.9905828914298016 1.6498345555713394 1.2528691874900573 1.0528848311670862 0.9281325071900374 1.104840483509568 0.9118790442453507 0.965980220458357 1.0 14.34234139778803 -5.856142001399774 2.0494767584757936 0.9899406345729873 1.805909459250618 0.9117053776544788 0.10489340919453118 0.07909693677551319 0.6776370802085431 0.031280800315351645 0.055942238955024176 1.3927013565015046e-06 5.856142001399774 0.8159688246776307 SLGEQDQMT(ph)LRPPEK ddPTM_PC-9_Lapatinib_30min_R1 1 SLGEQDQMTLRPPEK 15 1 P48681 P48681 NES Nestin 1 S(0.035)LGEQDQMT(0.965)LRPPEK 111.5 0.0038108000000000005 0.0 10698.0 22488.0 29222.0 20314.0 28311.0 24221.0 26529.0 25534.0 25259.0 22523.0 True False 10545.444558227067 22435.930417658594 26819.47996018204 21807.959325517462 26645.802641567556 23185.1242919087 27902.541812606083 26720.40285644988 22414.06543093819 26416.070539988978 0.39920564802638764 0.8493288350246795 1.0152713636792565 0.8255565222126546 1.0086966795924779 0.8776901264255321 1.056271475743028 1.011520726218542 0.8485011196880133 1.0 14.689128257410093 -4.767971621996318 3.1643870862650267 0.9536981381464473 0.30680834465220685 0.8305162811276873 0.07510823095540321 0.13378796055117095 1.9749669441091198 0.01832113123802758 0.22150904598377996 1.7061938727915697e-05 4.767971621996318 -0.6468897934942405 down SLGGEAAVR ddPTM_PC-9_AZD4547_30min_R2 1 SLGGEAAVR 9 0 Q9UG01-2;Q9UG01 Q9UG01-2 IFT172 Intraflagellar transport protein 172 homolog 0 99.375 0.019173 13117000.0 35535.0 57162.0 49861.0 72384.0 67790.0 56771.0 51900.0 56232.0 58734.0 55141.0 False True 46834.3908260836 75638.4986361652 49199.81056140133 55696.98712165202 58378.52864057608 53221.100395471316 56518.99945637764 47542.63648281094 61838.55933216252 53210.53037361416 0.8801714716474179 1.4214949203677274 0.924625449435444 1.0467286593570742 1.0971235999843483 1.0001986453016525 1.062176961205485 0.8934817253087598 1.1621488998130114 1.0 15.699424163141163 SLGGEAAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLGGEAAVR 9 0 Q9UG01-2;Q9UG01 Q9UG01-2 IFT172 Intraflagellar transport protein 172 homolog 0 99.375 0.019173 9532000.0 34517.0 35787.0 46906.0 46402.0 44492.0 51761.0 52057.0 43560.0 34590.0 33859.0 False True 40360.04635817452 39339.696851956454 48024.4169319956 43802.24637731374 35774.1119884944 49046.562039967204 47125.78409995767 42416.596155635045 35095.81331214914 39997.36867230346 1.0090675386384154 0.9835571228263719 1.200689408482277 1.095128200461972 0.8944116369651712 1.2262447172913638 1.1782221097106906 1.0604846659577083 0.8774530544668443 1.0 15.287617471342264 -8.137255167968087 6.036363064190276 0.9408852210417197 1.0854379195134032 0.2424594070588536 0.10107645650221485 0.3313610659789324 14.568014863247988 0.07242407940043112 0.02667584402300016 7.290290463252231e-09 8.137255167968087 0.1445526984716835 SLGGEAAVR ddPTM_PC-9_Lapatinib_30min_R1 1 SLGGEAAVR 9 0 Q9UG01-2;Q9UG01 Q9UG01-2 IFT172 Intraflagellar transport protein 172 homolog 0 88.94200000000001 0.044824 13529000.0 33810.0 31802.0 29009.0 29143.0 28492.0 31020.0 30547.0 27047.0 32683.0 21317.0 False True 33327.86320000535 31728.36442290905 26623.991997978257 31286.273438198088 26816.15657742725 29693.346911151817 32128.57419238107 28303.702359927953 29001.89637275237 25001.61504688296 1.333028411864955 1.2690525937389288 1.0648908859708872 1.251370096672961 1.072576972613236 1.1876571515668461 1.2850599504125497 1.1320749602316862 1.1600009166755065 1.0 14.609733672231622 -14.522878745280336 0.10896457018652937 0.4178643767610011 1.2984377169744143 0.3808505944699935 0.08148031187360029 203.29031231202922 1.470875351012708 26.781820735212722 1.0904733715840211 3.0000000000000132e-15 14.522878745280336 0.8805733402134133 SLGGES(ph)SGGTTPVGSFHTEAAR ddPTM_PC-9_AZD4547_30min_R2 2 SLGGESSGGTTPVGSFHTEAAR 22 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 S(0.056)LGGES(0.528)S(0.413)GGT(0.002)TPVGSFHTEAAR;S(0.004)LGGES(0.79)S(0.206)GGTTPVGSFHTEAAR 123.03 3.1993000000000003e-07 8037200.0 8681.9 8614.0 24292.0 54292.0 33053.0 28208.0 13389.2 37040.0 21399.2 30311.0 True False 11442.563605261716 11398.307044048974 23969.872207889173 41775.81820303836 28464.1614863101 26444.149300795372 14580.812861682687 31316.31909452479 22530.31802466734 29249.821115950377 0.3912011482019598 0.38968809412079797 0.8194878222628867 1.4282418356486073 0.9731396774521863 0.9040790094396499 0.4984923772313789 1.0706499356143933 0.770271993642423 1.0 14.8361401811371 -5.318269597083479 4.373290136527615 0.9438631935394743 0.3850628065826739 0.49563786450390945 0.22122869376016033 0.17333804758468824 6.900667581982296 0.06180169503295912 0.1420392699475111 4.80540950326864e-06 5.318269597083479 -0.5588003869568005 SLGGIS(ph)PSEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLGGISPSEDR 11 0 H3BV44;H3BRD5;B2RTY4-5;B2RTY4-2;B2RTY4;B2RTY4-4;H3BMM1 H3BV44 MYO9A Unconventional myosin-IXa 1 SLGGIS(0.861)PS(0.139)EDR;S(0.001)LGGIS(0.834)PS(0.164)EDR 112.5 0.0023526 3142800.0 30951.0 34609.0 34826.0 36696.0 42418.0 31939.0 41102.0 34919.0 31506.0 31052.0 True False 36190.392989884975 38044.75279708723 35656.38391834049 34640.04209003719 34106.4974001608 30264.062614603896 37208.52100728933 34002.41324973876 31966.71564650392 36681.48179250327 0.9866120783943177 1.0371651017888426 0.9720540767692684 0.9443468583408401 0.929801516555181 0.8250501652522957 1.0143679913959684 0.9269640044009335 0.8714674021984868 1.0 15.162764299058113 -5.658783290956315 2.24198800187084 0.92461150825553 1.0118375014105776 0.276052313253757 0.05300749028789968 0.37370000757836097 3.7961512547384433 0.015424839687966013 0.03221513093356874 2.193899398348453e-06 5.658783290956315 0.08722599315504764 SLGGIS(ph)PSEDR ddPTM_PC-9_Lapatinib_30min_R1 3 SLGGISPSEDR 11 0 H3BV44;H3BRD5;B2RTY4-5;B2RTY4-2;B2RTY4;B2RTY4-4;H3BMM1 H3BV44 MYO9A Unconventional myosin-IXa 1 SLGGIS(0.727)PS(0.273)EDR;SLGGIS(0.88)PS(0.12)EDR;SLGGIS(0.932)PS(0.068)EDR 127.52 0.00035618 5741400.0 42084.0 49690.0 54435.0 41487.0 56236.0 57840.0 58984.0 53301.0 67330.0 43423.0 True False 41483.874442739616 49574.94585794448 49959.564425176555 44538.09237657493 52928.309044229936 55366.31803162544 62037.90290907143 55777.55904486705 59746.5863836679 50928.60769248952 0.8145495493067892 0.9734204036615621 0.9809725160137086 0.8745201252211535 1.039264795217155 1.0871359053428502 1.218134673613318 1.0952107581981396 1.173143918334111 1.0 15.63618865632549 -6.551277842321613 2.4290162060088414 1.129365589861384 0.9201526460508289 0.6460954760622585 0.07048858667034812 0.17784657138845106 2.1206098448329724 0.024356715007074366 0.025652528213724768 2.810102476444766e-07 6.551277842321613 -0.209212943810555 SLGGIS(ph)PSEDRR ddPTM_PC-9_Lapatinib_30min_R1 1 SLGGISPSEDRR 12 1 H3BV44;H3BRD5;B2RTY4-5;B2RTY4-2;B2RTY4;B2RTY4-4;H3BMM1 H3BV44 MYO9A Unconventional myosin-IXa 1 SLGGIS(0.673)PS(0.326)EDRR 60.937 0.026543999999999998 6343100.0 20995.0 17256.0 24515.0 16515.0 18506.0 20358.0 19845.0 17507.0 23933.0 13579.0 True False 20695.60744998853 17216.04479220547 22499.47133063661 17729.568192424973 17417.513464195858 19487.335796815885 20872.47699766925 18320.439132445685 21237.4135143372 15926.112057119837 1.2994764431998624 1.0809948297776144 1.4127409910178375 1.1132389455026404 1.0936450404045275 1.2236091098017854 1.3105820757011515 1.150339710454031 1.3334964263825408 1.0 13.959106493210156 -11.84724089187786 2.034533919163456 3.910272222511239e-05 1.2188094620063736 0.2790924455953604 0.10779946244540156 2725263.2664949317 289918.1490887896 12556185.76546257 0.02745806602201787 1.4215400770170602e-12 11.84724089187786 1.2187703592841486 SLGGISPS(ph)EDR ddPTM_PC-9_AZD4547_30min_R2 1 SLGGISPSEDR 11 0 H3BV44;H3BRD5;B2RTY4-5;B2RTY4-2;B2RTY4;B2RTY4-4;H3BMM1 H3BV44 MYO9A Unconventional myosin-IXa 1 SLGGIS(0.215)PS(0.785)EDR 89.805 0.009082600000000001 4254600.0 10406.0 10800.0 22569.0 27388.0 19990.0 18749.0 16247.0 25959.0 17001.0 17232.0 True False 13714.891541753928 14290.888794489083 22269.720313677353 21074.11974038191 17214.733552516816 17576.62206610226 17692.95152539051 21947.633028476474 17899.638151770596 16628.712925012587 0.8247716827875629 0.8594103980827648 1.3392329529112066 1.2673331866041555 1.0352414904356637 1.057004360190971 1.064000058523899 1.3198636074511376 1.0764295608739693 1.0 14.021388886805973 -5.161312903609319 7.659723483785999 1.1504633978338503 0.8359807151997944 0.5189679289784448 0.1166023976319463 0.21808322251247778 14.748220936257045 0.030555552671369102 0.08195269367435583 6.8974267401539815e-06 5.161312903609319 -0.3144826826340559 SLGGISPS(ph)EDRR ddPTM_PC-9_AZD4547_30min_R2 1 SLGGISPSEDRR 12 1 H3BV44;H3BRD5;B2RTY4-5;B2RTY4-2;B2RTY4;B2RTY4-4;H3BMM1 H3BV44 MYO9A Unconventional myosin-IXa 1 S(0.001)LGGIS(0.23)PS(0.769)EDRR 58.723 0.030751999999999998 7004700.0 15780.0 14800.0 32776.0 40951.0 27969.0 24911.0 17647.0 27555.0 19704.0 24141.0 True False 20797.711755609944 19583.810570225778 32341.36882454202 31510.379636643054 24085.9871300822 23353.311231994947 19217.54881323114 23297.007900907945 20745.51321348674 23295.830937948514 0.8927653969934519 0.8406573099877748 1.388289986765764 1.3526188321238706 1.0339183519247874 1.0024674069020993 0.8249351081066646 1.000050522471706 0.8905247152911232 1.0 14.507784170338278 -6.742954642173443 3.0238044756518585 0.930478722985571 1.122768638213513 0.1904293072626312 0.16849092630839693 0.45383267126468296 8.544338518206942 0.06801333252744109 0.06394865963118244 1.8073628775944428e-07 6.742954642173443 0.19228991522794192 SLGGLQPEGDPPS(ph)RPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLGGLQPEGDPPSRPR 16 1 A0A1B0GUA9 A0A1B0GUA9 1 SLGGLQPEGDPPS(1)RPR 53.376999999999995 0.03569 2037300.0 673.24 1097.8 787.06 2186.6 2566.0 751.41 933.14 2357.3 665.24 440.7 True False 787.2062349038853 1206.7823288925522 805.8264953416722 2064.091891052849 2063.2107201851245 712.0047368182949 844.7462238514419 2295.423372765807 674.9678764895663 520.5954214207193 1.5121266966881455 2.3180809496925847 1.5478939348766254 3.9648675461260976 3.9631749248861343 1.3676738356154081 1.6226539633139803 4.409226970343944 1.296530566188155 1.0 9.02401881322887 -8.496996422866571 24.60385736470156 0.9999980709918158 2.5814750695950783 0.22114819147740905 1.0879967813138154 764.1010344492299 726358.7779419224 1.0721648215975979 0.2768318112418821 3.184223748967737e-09 8.496996422866571 1.5814769986032626 SLGGQQGS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 SLGGQQGSPK 10 0 A0A0C4DGT3;A0A3B3IU98;Q6DN90-2;A0A2R8Y7T6;A0A3B3IRZ4;Q6DN90;Q6DN90-3;A0A2R8Y695 A0A0C4DGT3;A0A2R8Y7T6 IQSEC1 IQ motif and SEC7 domain-containing protein 1 1 SLGGQQGS(1)PK;SLGGQQGS(1)PK 87.21600000000001 0.010768999999999999 29315000.0 135477.0 174911.0 207840.0 245700.0 213430.0 192589.0 226130.0 216010.0 182492.0 219070.0 True False 178555.86790334378 231447.56017897016 205083.9057997563 189057.66102715922 183798.92856996832 180546.37938495714 246255.1319281441 182630.61791599114 192138.1545551979 211400.42597971848 0.8446334347522755 1.0948301504424356 0.970120589158282 0.8943106909599946 0.8694349962549356 0.8540492695236033 1.1648752872038657 0.8639084669276519 0.9088825325906932 1.0 17.689618758244485 -10.206801570985053 18.341429743213524 0.9999999999987447 0.9443136971682431 0.028026120591836623 0.1028979707994725 0.0 0.0 0.09916493366766273 0.024051029168773084 6.211527739158236e-11 10.206801570985053 -0.05568630283050158 SLGGQQGS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLGGQQGSPK 10 0 A0A0C4DGT3;A0A3B3IU98;Q6DN90-2;A0A2R8Y7T6;A0A3B3IRZ4;Q6DN90;Q6DN90-3;A0A2R8Y695 A0A0C4DGT3;A0A2R8Y7T6 IQSEC1 IQ motif and SEC7 domain-containing protein 1 1 SLGGQQGS(1)PK;SLGGQQGS(1)PK 105.65 0.0024295000000000002 23937000.0 160457.0 179359.0 183690.0 237570.0 247490.0 233250.0 233210.0 215680.0 189717.0 179283.0 True False 187619.20092979108 197164.57617766366 188069.86624820394 224259.7231123322 198996.11112183076 221017.9593868422 211118.66050581343 210018.62853185012 192491.25221569848 211785.58869655273 0.8858921992025277 0.9309631377239831 0.8880201311415539 1.0588998264355582 0.9396111999242461 1.0435930071876498 0.99685092741747 0.9916568441904972 0.9088968394893986 1.0 17.69224489651785 -5.737927475401805 24.999991635157677 0.9912599283310904 0.9045589120124292 0.4813437786628052 0.04265226617730596 201.90745340395114 214684.70734420686 0.011135630472388454 0.01927340921666472 1.8284055235090572e-06 5.737927475401805 -0.08670101631866123 SLGGQQGS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 SLGGQQGSPK 10 0 A0A0C4DGT3;A0A3B3IU98;Q6DN90-2;A0A2R8Y7T6;A0A3B3IRZ4;Q6DN90;Q6DN90-3;A0A2R8Y695 A0A0C4DGT3;A0A2R8Y7T6 IQSEC1 IQ motif and SEC7 domain-containing protein 1 1 SLGGQQGS(1)PK;S(0.01)LGGQQGS(0.99)PK 96.06700000000001 0.0056738 40981000.0 287250.0 253880.0 180261.0 195646.0 190351.0 186266.0 156052.0 170483.0 170643.0 124589.0 True False 283153.7623248011 253292.15645834038 165440.63640758247 210034.45949592316 179154.928424465 178299.83738725347 164131.60899169964 178404.2625587904 151423.38838954776 146124.04264559288 1.9377629936748884 1.7334050705993092 1.1321931245006667 1.43737098764327 1.2260468926320685 1.220195076450898 1.1232347943574355 1.2209097101938897 1.036266076738705 1.0 17.156834047183615 -1.5228787452803723 0.47414210840140214 1.11209550715622 24.519338511250776 0.8345030867104205 0.11860902370737504 35.79934089516281 0.40721313191718944 0.06748666316332835 823.1541429363064 0.029999999999997605 1.5228787452803723 23.407243004094557 SLGLDINMDS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 SLGLDINMDSR 11 0 Q96H22-5;Q96H22-4;Q96H22;Q96H22-3 Q96H22-5 CENPN Centromere protein N 1 SLGLDINMDS(1)R 66.267 0.037537 1014500.0 0.0 0.0 2227.6 2457.2 1092.3 367.14 0.0 2519.8 937.31 2735.9 True False 0.0 0.0 2198.0605685120167 1890.7305033615603 940.6529994704412 344.18267776141573 0.0 2130.422809243615 986.8542930437097 2640.116973743148 0.0 0.0 0.8325618108487121 0.7161540652045011 0.3562921676673996 0.13036645011733508 0.0 0.80694258263228 0.3737918822757885 1.0 11.3663861361021 -8.872649679927735 0.9558913684600396 0.9952181950850318 0.33490714427298424 0.2835453576114668 0.3125281935592095 1.7234731164014296 2.766062642447631 0.32620247224880666 0.10642182989016974 1.3407577625701492e-09 8.872649679927735 -0.6603110508120476 SLGLSLS(ph)GGDQEDAGR ddPTM_PC-9_AZD4547_30min_R2 3 SLGLSLSGGDQEDAGR 16 0 H0YE82;H7C1L7;H0YEB7;C9JEV6;H7C3G9;Q9UJ70;Q9UJ70-2 H0YE82 NAGK N-acetyl-D-glucosamine kinase 1 S(0.004)LGLS(0.001)LS(0.995)GGDQEDAGR;SLGLS(0.042)LS(0.958)GGDQEDAGR;SLGLS(0.013)LS(0.987)GGDQEDAGR 99.891 0.0018512000000000001 11210700.0 38166.0 32316.7 43510.9 64460.0 68185.0 54828.0 45718.2 49949.9 48430.1 46107.4 True False 50301.99409788397 42762.44128748752 42933.917036483 49599.74289707234 58718.68970877238 51399.5964926265 49787.03123211108 42231.29068951411 50990.01621399125 44493.19396000033 1.1305548022267358 0.9611007320789609 0.9649547091422762 1.1147714623873222 1.3197229617087247 1.1552237975730641 1.1189808328183843 0.9491629377625782 1.1460183384414164 1.0 15.441297046165174 -4.407229021797749 20.896007339853085 1.0854199845710846 12.91100315863362 0.01649070392151264 0.11011819712841463 2497.9675061767816 452917.51706979255 0.028902579915628508 4938.805414921032 3.915353495534355e-05 4.407229021797749 11.825583174062535 SLGLSLS(ph)GGDQEDAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLGLSLSGGDQEDAGR 16 0 H0YE82;H7C1L7;H0YEB7;C9JEV6;H7C3G9;Q9UJ70;Q9UJ70-2 H0YE82 NAGK N-acetyl-D-glucosamine kinase 1 SLGLS(0.013)LS(0.987)GGDQEDAGR 94.92200000000001 0.0025336 3841300.0 11871.0 12329.0 12042.0 9434.0 13491.0 10496.0 12135.0 13211.0 12837.0 9641.8 True False 13880.525837062609 13552.94164047758 12329.126949539312 8905.443565440672 10847.535395953828 9945.571282848008 10985.484950208169 12864.225248211544 13024.71683978197 11389.782015553199 1.2186823082398066 1.1899210732892431 1.082472599800716 0.7818800705123184 0.9523918351677924 0.8732011964115675 0.9645035291463044 1.129453156403251 1.1435439960129352 1.0 13.47545251570085 -5.466254368841021 4.4863738473015955 0.9743100442747179 1.196497353818915 0.44070071042887604 0.10142979992066757 0.2141996495497841 8.83399317033593 0.030185919103099534 0.06367110349553909 3.4177920178286484e-06 5.466254368841021 0.22218730954419708 SLGLSLS(ph)GGDQEDAGR ddPTM_PC-9_Lapatinib_30min_R1 2 SLGLSLSGGDQEDAGR 16 0 H0YE82;H7C1L7;H0YEB7;C9JEV6;H7C3G9;Q9UJ70;Q9UJ70-2 H0YE82 NAGK N-acetyl-D-glucosamine kinase 1 SLGLS(0.014)LS(0.986)GGDQEDAGR;SLGLS(0.014)LS(0.986)GGDQEDAGR 105.89 0.0010812 18135700.0 39096.0 31654.0 36803.0 32253.0 38631.0 33170.0 29520.0 29067.0 37596.0 27132.0 True False 38538.48387067168 31580.70710781597 33777.199403688326 34624.99321285392 36358.800531468216 31751.396423046604 31048.40115753066 30417.558934300505 33361.54257656881 31821.730048882513 1.211074439116645 0.9924258379196763 1.0614507555623767 1.0880927328484409 1.1425777440640765 0.9977897610931943 0.9756980877480919 0.9558738285936996 1.0483887119060131 1.0 14.957724652210679 -6.83466757024065 8.630025302786846 0.9910669243914149 1.0903868643973211 0.44700157606583213 0.057096090269424124 0.28125038864588237 29.942814639681806 0.01982627814983232 0.01750400613933567 1.4632968232320043e-07 6.83466757024065 0.09931994000590627 SLGNILQAKPT(ph)SSPAKGPPQK ddPTM_PC-9_AZD4547_30min_R2 1 SLGNILQAKPTSSPAKGPPQK 21 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 SLGNILQAKPT(0.571)S(0.204)S(0.225)PAKGPPQK 43.696000000000005 0.040988 313250000.0 91907.0 102470.0 81432.0 121180.0 96170.0 85326.0 80692.0 93993.0 82286.0 103130.0 True False 121131.5142156426 135591.42358993477 80352.15847327645 93243.82321233682 82818.45551503447 79990.55173141172 87873.43167888286 79468.5415942674 86635.4699698016 99519.45009032887 1.2171642237341296 1.3624615436165006 0.807401552162364 0.9369406998099771 0.8321836127497113 0.8037680238265812 0.8829774641954362 0.7985227161337582 0.8705380696051565 1.0 16.602690893211822 -5.263140030726122 24.99998980016815 0.8589781685118081 1.2898129078431675 0.8581391441485946 0.06878351146307599 42.114623746128395 619106.2393555688 0.016543307480160804 0.03757225528745092 5.455819192972376e-06 5.263140030726122 0.4308347393313594 SLGNILQAKPT(ph)SSPAKGPPQK ddPTM_PC-9_Lapatinib_30min_R1 1 SLGNILQAKPTSSPAKGPPQK 21 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 SLGNILQAKPT(0.333)S(0.333)S(0.333)PAKGPPQK 92.428 0.0033713000000000003 50508000.0 67372.0 45815.0 56227.0 52182.0 58628.0 53326.0 35228.0 42342.0 52038.0 41090.0 True False 66411.26292548819 45708.91818236519 51604.23310249662 56019.63835404907 55179.61630708286 51045.3712889775 37051.93346807216 44309.363897070616 46176.93245556678 48192.351751016606 1.378045696308798 0.9484683050646303 1.0707971540610288 1.1624176102355774 1.1449870010943979 1.059200670527574 0.76883430921776 0.9194273009541586 0.9581796857339026 1.0 15.556516584793012 -7.053247666602304 6.634492343188596 0.904964998493919 1.1253793753503623 0.4701094870956234 0.11424901983173731 0.213844099736616 21.442824860370283 0.04256489635621061 0.033274335906985406 8.846109958168279e-08 7.053247666602304 0.22041437685644327 SLGNILQAKPTS(ph)SPAK ddPTM_PC-9_AZD4547_30min_R2 1 SLGNILQAKPTSSPAK 16 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 SLGNILQAKPT(0.165)S(0.417)S(0.417)PAK 60.45399999999999 0.02143 259920000.0 197800.0 192600.0 179140.0 156760.0 142370.0 208160.0 228480.0 196720.0 203750.0 178190.0 True False 260696.28550441313 254854.18350172223 176764.48655200354 120621.40391785694 122604.38298508352 195143.72229344764 248814.27737559035 166321.4441758889 214519.80903613073 171951.62233681447 1.5161025058185718 1.4821272404311507 1.0279896412129323 0.7014845354676956 0.7130167271404347 1.1348757263319393 1.447001627517182 0.9672571966207023 1.247559087380605 1.0 17.391643201969067 -5.256170890318552 6.598131334363298 1.0237749472675073 1.5026486605184128 0.44123288458988175 0.21120260241134206 0.1363511488270363 34.144020262264654 0.06092229406650305 0.1474866893088432 5.544075164952361e-06 5.256170890318552 0.47887371325090555 SLGNILQAKPTS(ph)SPAKGPPQK ddPTM_PC-9_AZD4547_30min_R2 2 SLGNILQAKPTSSPAKGPPQK 21 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 SLGNILQAKPT(0.039)S(0.576)S(0.385)PAKGPPQK;SLGNILQAKPT(0.111)S(0.445)S(0.445)PAKGPPQK 128.38 4.9977e-05 122621000.0 65196.0 62293.0 80820.0 103228.0 93818.0 82055.0 70758.0 70426.0 80880.0 79646.0 True False 85926.97183895724 82427.99404399144 79748.27399315011 79430.37945670167 80792.99011655939 76924.08787850138 77055.3249235911 59543.279928482836 85155.1516802074 76857.6177823556 1.1180020187756028 1.0724765667003882 1.037610536134235 1.0334743874267815 1.0512034128529448 1.0008648472079111 1.0025723818528356 0.774721903261388 1.1079598111061502 1.0 16.22990064001413 -6.968711149586728 1.7503350767893715 0.9521813640580926 1.063061812111738 0.2187753917238029 0.08042313045043999 0.4865211106789608 3.0216904293874194 0.03580007726257649 0.027892558138328024 1.0747039631500723e-07 6.968711149586728 0.11088044805364528 SLGNILQAKPTS(ph)SPAKGPPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLGNILQAKPTSSPAKGPPQK 21 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 SLGNILQAKPT(0.194)S(0.612)S(0.194)PAKGPPQK;SLGNILQAKPT(0.123)S(0.438)S(0.438)PAKGPPQK 132.36 6.581699999999999e-06 85055000.0 82601.0 62697.0 74710.0 104775.0 93249.0 111635.0 103628.0 110908.0 103059.0 79750.0 True False 96583.71785588484 68921.1438099621 76491.36973925262 98904.79643513335 74977.52784354739 105780.66407781423 93811.60563825059 107996.78251673945 104566.042906527 94208.04369934734 1.0252173175797934 0.731584492189594 0.8119409631662114 1.0498551137605094 0.7958718268561904 1.1228411070226594 0.9957918873428481 1.146364771795889 1.1099481403120508 1.0 16.523562625265754 -6.768559868828108 24.999713580062366 1.079187170599514 0.8798216462016986 0.46905354174231806 0.10211320281446061 145.56889277739978 511082.51880958537 0.03509952739659821 0.031598418618224544 1.7038844174251325e-07 6.768559868828108 -0.1993655243978154 SLGNILQAKPTS(ph)SPAKGPPQK ddPTM_PC-9_Lapatinib_30min_R1 1 SLGNILQAKPTSSPAKGPPQK 21 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 S(0.001)LGNILQAKPT(0.13)S(0.435)S(0.435)PAKGPPQK 42.638999999999996 0.031285 268280000.0 108870.0 72816.0 80493.0 72045.0 84346.0 66025.0 54119.0 50511.0 73617.0 63090.0 True False 107317.49383568743 72647.39902580177 73875.17625196555 77343.42963507448 79384.93411061636 63201.26466179231 56921.01701369928 52857.92545947131 65325.47823862285 73995.02243785921 1.450333958960717 0.9817876477679405 0.9983803480025388 1.045251789740685 1.0728415438657861 0.8541285964859128 0.769254676035829 0.7143443399028797 0.8828361163547586 1.0 16.17514060507829 -6.77312280065763 3.6157154514023935 0.8163593043592239 1.0967514657673356 0.46296353109910127 0.14191303886492954 0.2094924694789364 5.839063748602546 0.050756579848039024 0.04698732918880511 1.6860762048189326e-07 6.77312280065763 0.28039216140811174 SLGNILQAKPTSS(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 1 SLGNILQAKPTSSPAK 16 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 SLGNILQAKPTS(0.007)S(0.992)PAK 185.14 3.3330999999999996e-07 21071000.0 74208.0 71844.0 82104.0 63653.0 71190.0 79932.0 81029.0 80836.0 77953.0 80578.0 True False 97804.60037771259 95066.16801400678 81015.2473141994 48978.78427904667 61306.49732884808 74933.83940411129 88240.42402602729 68344.65362648501 82073.43643579628 77756.98874603452 1.2578239198171168 1.2226060904249587 1.0419030960523281 0.6298955896944313 0.7884371336586078 0.963692661104148 1.1348230615544177 0.8789519081006141 1.05551202225513 1.0 16.246684729083654 -5.379825887254989 3.8357506935901946 0.9171507291619478 1.240891696017115 0.4651419606049164 0.1341921788012382 0.2106174866619761 5.392302053994428 0.03899118388048233 0.08875891801995027 4.170365438352371e-06 5.379825887254989 0.3237409668551672 SLGNILQAKPTSS(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLGNILQAKPTSSPAK 16 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 SLGNILQAKPTS(0.029)S(0.97)PAK 123.43 1.9554e-05 181090000.0 146310.0 192280.0 172070.0 187650.0 187830.0 141190.0 171570.0 149050.0 117470.0 103050.0 True False 171077.39324577764 211368.2876657496 176172.80137910935 177136.5788695083 151026.05984893712 133785.74784921034 155317.64754076742 145137.59543152878 119187.77651859356 121732.14925664899 1.4053591782487438 1.7363390768704818 1.4472167168237755 1.4551339145097129 1.2406423510237012 1.0990173809151158 1.275896700166772 1.1922700479520318 0.9790985967668154 1.0 16.89335070615278 -6.235315250728734 1.2319616951172399 1.117000322030941 1.5714767316636027 0.7387490430799588 0.11354116577413133 0.23496653484945282 0.7292274576096238 0.045007051840619414 0.06690932125247079 5.816808272415684e-07 6.235315250728734 0.45447640963266167 SLGNILQAKPTSS(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 2 SLGNILQAKPTSSPAK 16 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 SLGNILQAKPTS(0.071)S(0.929)PAK;SLGNILQAKPT(0.021)S(0.257)S(0.723)PAK 291.06 1.4440999999999997e-96 253578000.0 309630.0 483750.0 466760.0 481970.0 536860.0 455100.0 488930.0 506300.0 431840.0 468660.0 True False 305214.6194208121 482629.9065965105 428384.7945457042 517415.6816047887 505282.95030737005 435636.4338899163 514244.4030471363 529824.5463390208 383201.6317232016 549667.256549804 0.555271604382273 0.8780401249037846 0.7793529438784923 0.9413252753175537 0.9192524100470729 0.7925457241611122 0.9355558238542119 0.9639005053069133 0.6971520081594684 1.0 19.068199015627677 -4.761287858775991 24.49456404099979 0.876665872131146 0.5552711963391848 0.537065709813675 0.09003154383494899 2.100006986115455 338044.08896399714 0.02121962208740778 0.11918918280704109 1.732655179727545e-05 4.761287858775991 -0.32139467579196124 SLGNILQAKPTSS(ph)PAKGPPQK ddPTM_PC-9_Lapatinib_30min_R1 1 SLGNILQAKPTSSPAKGPPQK 21 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 SLGNILQAKPT(0.068)S(0.266)S(0.666)PAKGPPQK 128.29 4.907e-05 52842000.0 64253.0 38948.0 42928.0 40113.0 39158.0 37369.0 34314.0 30784.0 41787.0 33081.0 True False 63336.74043744289 38857.81829895798 39398.62554687205 43063.04383304529 36854.803427590065 35770.81498139366 36090.611020308505 32214.337022517157 37080.50802338229 38799.00677233825 1.6324320055171828 1.001515799797784 1.0154544877411988 1.109900675698407 0.9498903836338844 0.9219518218929372 0.9301941988380822 0.8302876723505295 0.9557076613058774 1.0 15.243732100442191 -2.730061219443763 1.373653224278157 0.9512816908555382 199.99999999615906 0.8806745787585238 0.07282578699966444 139.60362232561283 1.1981544514052 0.022614599573254124 86652.63388712384 0.001861824669813142 2.730061219443763 199.0487183053035 SLGPPGPPFNIT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLGPPGPPFNITPR 14 0 Q9NZM1-5;Q9NZM1-2;Q9NZM1-6;Q9NZM1 Q9NZM1-5 MYOF Myoferlin 1 SLGPPGPPFNIT(1)PR;SLGPPGPPFNIT(1)PR 104.94 0.0024909000000000003 5818500.0 21925.3 26307.1 20416.8 21016.5 28007.1 26319.0 22146.1 20911.7 21536.7 18683.3 True False 25636.820245585764 28918.69503043291 20903.61394314517 19839.013641412315 22519.309805649595 24938.78530804846 20048.26108412072 20362.79003277764 21851.633494066555 22070.434393078573 1.1615911036905386 1.3102911576358458 0.9471319671759916 0.8988954765491138 1.020338313445783 1.129963500667183 0.9083763702633774 0.9226275147155029 0.9900862441076087 1.0 14.429827404752515 -5.2675669611198925 24.986057815569747 0.9761592558456981 1.2359411367574744 0.6744933094411613 0.071901450746519 255.25792519524893 1040852.4493170325 0.019580118032715765 0.0424568628100514 5.400488416292424e-06 5.2675669611198925 0.25978188091177634 SLGS(ph)PLLHER ddPTM_PC-9_AZD4547_30min_R2 3 SLGSPLLHER 10 0 H7C3L4;E7EQA9;Q92844;E7EV32;E7EMT6;E7ENY2;E7EVA2;E7EW82 H7C3L4 TANK TRAF family member-associated NF-kappa-B activator 1 S(0.043)LGS(0.957)PLLHER;S(0.018)LGS(0.982)PLLHER;S(0.161)LGS(0.839)PLLHER 98.368 0.0027125 9250300.0 45590.2 48630.9 51711.0 71123.0 62194.0 58170.4 54363.7 64962.0 54496.2 60414.0 True False 60086.93526493077 64349.8873959184 51025.27835263285 54726.6911893962 53559.43664658483 54532.99569224994 59201.96398355831 54923.615578253775 57376.75787580271 58298.92424859044 1.0306697085647092 1.1037920206130434 0.8752353325604725 0.9387255750387091 0.9187036868502731 0.9354031209858636 1.0154898181502843 0.9421034141909013 0.9841821031061302 1.0 15.831181642125435 -5.249992387054168 24.982190985674386 0.9492840978244269 1.0672308711354679 0.5495747276815934 0.0419770437779259 525.4356850054917 1146718.0636958962 0.010647842892159544 0.02767131370194726 5.623511828140326e-06 5.249992387054168 0.11794677331104098 SLGS(ph)PLLHER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLGSPLLHER 10 0 H7C3L4;E7EQA9;Q92844;E7EV32;E7EMT6;E7ENY2;E7EVA2;E7EW82 H7C3L4 TANK TRAF family member-associated NF-kappa-B activator 1 S(0.156)LGS(0.844)PLLHER;S(0.051)LGS(0.949)PLLHER;S(0.001)LGS(0.999)PLLHER 98.94200000000001 0.002587 6677800.0 24363.1 34444.5 36962.7 36418.6 42340.5 38212.6 39124.1 35215.0 30904.2 32617.6 True False 28487.29163684102 37863.922324229825 37844.030949820364 34378.18391269425 34044.18296882242 36208.66398656227 35417.98201404525 34290.64356337669 31356.11545999768 38530.91267922045 0.7393360202496343 0.9826894742789125 0.9821732297099073 0.8922234518268822 0.8835550627167545 0.939730244336762 0.9192095268780387 0.8899515007302041 0.8137911427389545 1.0 15.233728738975167 -4.748641037181785 24.989153029631677 0.9192754321222762 0.7393355935813635 0.5103198739922887 0.053765163311530945 540.1745723343117 1054644.0855612573 0.013654480523714825 0.2437101638692705 1.783852588136897e-05 4.748641037181785 -0.17993983854091278 SLGS(ph)PLLHER ddPTM_PC-9_Lapatinib_30min_R1 4 SLGSPLLHER 10 0 H7C3L4;E7EQA9;Q92844;E7EV32;E7EMT6;E7ENY2;E7EVA2;E7EW82 H7C3L4 TANK TRAF family member-associated NF-kappa-B activator 1 S(0.005)LGS(0.995)PLLHER;S(0.067)LGS(0.933)PLLHER;SLGS(1)PLLHER;SLGS(1)PLLHER 110.92 0.00094625 12413900.0 93488.2 98920.3 84876.0 81174.6 87153.4 80328.1 86463.29999999999 80912.9 80732.3 63363.6 True False 92155.04112436395 98691.25612299524 77897.82291083453 87144.45087452725 82027.20836217694 76892.65441694687 90939.94660582392 84672.4087210637 71639.37822519225 74315.91383331016 1.2400445122839607 1.3279962666456437 1.048198412597853 1.1726216684893545 1.103763704583693 1.0346727968577 1.2236941176529337 1.1393577008416131 0.9639843544934219 1.0 16.181383558685464 -1.5228787452803376 0.2383973826778203 1.0345998193576929 2.4820162859264143 0.4311839255328065 0.08354769768493496 52.41959613342666 0.6981829924171069 0.11766281661034769 29.952065137177534 0.029999999999999995 1.5228787452803376 1.4474164665687215 SLGS(ph)SPVK ddPTM_PC-9_Lapatinib_30min_R1 1 SLGSSPVK 8 0 Q9HCM1 Q9HCM1 KIAA1551 Uncharacterized protein KIAA1551 1 SLGS(0.5)S(0.5)PVK 87.806 0.011448999999999999 3091700.0 36143.0 34602.0 30667.0 26639.0 30178.0 30819.0 27088.0 28442.0 31891.0 28031.0 True False 35627.59419218557 34521.881194940535 28145.677638043355 28598.12092509893 28402.98937223079 29500.94321259794 28490.48409739807 29763.519152625795 28299.099752882128 32876.1210010403 1.0836921482025876 1.0500594396111438 0.8561130930608493 0.869875157236281 0.8639397990818939 0.8973364957400065 0.8666011448399447 0.9053233242353618 0.8607797663229996 1.0 15.00475246741656 -5.208770402724155 5.52231245637892 0.8843827191971879 1.0718072859668577 0.7492897375976969 0.04087653068518764 0.08688673133086874 6.025151183196024 0.009579118075735102 0.026014373792568404 6.1834321155788755e-06 5.208770402724155 0.1874245667696698 SLGS(ph)VQAPSYGAR ddPTM_PC-9_AZD4547_30min_R2 1 SLGSVQAPSYGAR 13 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.124)LGS(0.875)VQAPSYGAR 172.09 0.00021313 6070800.0 12129.0 11848.0 13066.0 20434.0 11676.0 17776.0 14510.0 18330.0 14957.0 15967.0 True False 15985.769701127552 15677.63429973209 12892.736302827258 15723.257002152917 10054.98894243054 16664.46390991699 15801.361890405384 15497.519681496738 15747.596484679314 15408.00018997656 1.0374980207702005 1.0174996174994169 0.8367559802611134 1.0204605924383 0.6525823480305809 1.081546190579476 1.025529705060928 1.0058099357746904 1.022040257691824 1.0 13.911392005631507 SLGS(ph)VQAPSYGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLGSVQAPSYGAR 13 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.022)LGS(0.974)VQAPS(0.003)YGAR;S(0.029)LGS(0.967)VQAPS(0.005)YGAR;S(0.001)LGS(0.998)VQAPS(0.001)YGAR 162.76 0.0003343 128134100.0 106216.2 90776.0 111876.0 122057.0 105961.0 89506.2 102332.0 114678.0 101886.0 72426.8 True False 124196.50479442396 99787.64136231577 114543.54813209247 115218.54200413314 85198.7026974029 84812.33730534025 92638.37214047792 111667.82401138482 103375.89000062532 85557.20550976653 1.4516194638947935 1.1663265620675842 1.3387948735541286 1.3466842601700064 0.9958097881969427 0.9912939161583386 1.082765286553253 1.30518316190958 1.20826632175153 1.0 16.384601741165994 -6.247446052018415 24.817975598859867 1.1064598883588668 1.315385508249221 0.49005239935361744 0.11382581591935341 749.8729737269166 1329942.8926398878 0.03614747129173713 0.04642562699674484 5.656580186613617e-07 6.247446052018415 0.2089256198903542 SLGS(ph)VQAPSYGAR ddPTM_PC-9_Lapatinib_30min_R1 1 SLGSVQAPSYGAR 13 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.001)LGS(0.864)VQAPS(0.135)YGAR 147.83 0.00011209 5437700.0 13572.0 14150.0 11804.0 12608.0 10874.0 10526.0 7547.8 8959.7 9901.9 7573.0 True False 13378.460791200014 14117.236544373414 10833.520684757674 13535.234379055042 10234.412699106553 10075.827517304448 7938.588152330965 9376.000370992952 8786.643750370438 8881.98295961179 1.5062470680291367 1.5894239618075605 1.219718697279642 1.523897809824962 1.152266644244257 1.1344119396672245 0.8937855643755864 1.055620171039233 0.9892659995324378 1.0 13.11666608810997 -6.465038809548459 1.1728645301254284 0.983890600869962 1.4855677884011742 0.795983783216043 0.10649737077276357 0.20028774174105107 0.577061516035692 0.04661905104777973 0.05603208960119809 3.427371574014439e-07 6.465038809548459 0.5016771875312122 SLGSAGPSGT(ph)LPR ddPTM_PC-9_AZD4547_30min_R2 2 SLGSAGPSGTLPR 13 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 SLGS(0.008)AGPS(0.026)GT(0.965)LPR;SLGSAGPS(0.002)GT(0.998)LPR 135.04 0.00012034 73870000.0 68961.0 88431.0 148904.0 163916.0 134151.0 155940.0 119574.0 141642.0 139380.0 146003.0 True False 90889.16352209252 117014.59138754304 146929.43566785494 126127.69867695501 115526.44926481675 146189.04714854035 130215.85435446828 119754.48350935928 146747.34225009053 140891.47940985434 0.6451004979349765 0.8305299360733288 1.042855368424631 0.8952116849454652 0.8199676073295353 1.0376003414888941 0.9242280292598065 0.8499767623348792 1.041562931021552 1.0 17.104224839917954 -4.883481488266275 3.2865187729215743 0.9416509018813616 0.6338299374034172 0.5978554253134216 0.07713223821176943 0.18880010817947018 3.4671687525962502 0.019267713031227665 0.12869226282775348 1.3077312795715707e-05 4.883481488266275 -0.3078209644779444 SLGSAGPSGT(ph)LPR ddPTM_PC-9_Lapatinib_30min_R1 1 SLGSAGPSGTLPR 13 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 SLGSAGPS(0.007)GT(0.993)LPR 159.66 0.00066425 43050000.0 114570.0 89870.0 81861.0 69567.0 94041.0 83158.0 71979.0 58461.0 80261.0 54565.0 True False 112936.21079043536 89661.91153659645 75130.70457259823 74683.189248709 88509.69327171959 79601.526190766 75705.72042404821 61177.31148237318 71221.1609942012 63996.487546707685 1.7647251453919113 1.4010442599862518 1.1739816895070103 1.166988878791225 1.3830398614786632 1.2438421113763316 1.1829668053077846 0.9559479563268697 1.112891718349708 1.0 15.965705104380744 -1.5228787452803376 0.6497373099970993 1.1296786113989252 56.30386198850065 0.7523815831630564 0.11005114118744022 120.77868079299812 0.7802885986578222 0.05089856377469387 9584.575824730959 0.029999999999999995 1.5228787452803376 55.17418337710173 SLGSASPGPGQPPLS(ph)SPTR ddPTM_PC-9_AZD4547_30min_R2 1 SLGSASPGPGQPPLSSPTR 19 0 Q9C0B5;Q9C0B5-2 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5 1 SLGSASPGPGQPPLS(0.499)S(0.499)PT(0.002)R 259.34 8.737399999999999e-66 32283000.0 48948.0 84542.0 91311.0 99085.0 92688.0 65282.0 88057.0 104090.0 65256.0 72654.0 True False 64512.44581835205 111868.54819108303 90100.15647845244 76242.48409798976 79819.87111133966 61199.90622002709 95893.9024109876 88005.28225024512 68705.2989372357 70110.40557415654 0.9201550795497329 1.5956054921513534 1.2851181752636207 1.0874631728859028 1.138488223790309 0.8729076050672006 1.3677556366374115 1.255238527427444 0.9799586576997527 1.0 16.097340960107104 -6.842146280763742 0.09359405570660526 0.8226650736961937 1.5118945720510244 0.07484593309225895 0.20637875502901384 66.32937888352507 2.719503925089654 7.443253181292892 11.791760279067846 1.438314038105728e-07 6.842146280763742 0.6892294983548307 SLGSASPGPGQPPLS(ph)SPTR ddPTM_PC-9_Lapatinib_30min_R1 3 SLGSASPGPGQPPLSSPTR 19 0 Q9C0B5;Q9C0B5-2 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5 1 SLGSASPGPGQPPLS(0.438)S(0.438)PT(0.123)R;SLGSASPGPGQPPLS(0.433)S(0.433)PT(0.135)R;SLGSASPGPGQPPLS(0.485)S(0.257)PT(0.257)R 111.73 0.00072393 8007300.0 172234.0 87590.0 73316.0 48150.0 54700.0 47527.0 39004.0 39875.0 66998.0 37338.8 True False 169777.91157615292 87387.19073651376 67288.24148794425 51691.11162369135 51482.653544337714 45494.38100084822 41023.43627196228 41727.738070844316 59451.979719782845 43792.76182917637 3.8768486956454193 1.995471102676451 1.5365151380590552 1.180357425853256 1.175597322341932 1.038856173956541 0.9367629388615297 0.9528455463396633 1.3575754813475527 1.0 15.418404817045234 -2.3547311369626724 0.8489393776802047 1.0557695166493488 199.9999999998366 0.9767952866913557 0.12928344498720878 17.490876490585237 0.2390310455075283 0.04472199525783732 6486.143590914294 0.004418438994311151 2.3547311369626724 198.94423048318725 up SLGSASPGPGQPPLSS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 2 SLGSASPGPGQPPLSSPTR 19 0 Q9C0B5;Q9C0B5-2 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5 1 SLGSASPGPGQPPLS(0.109)S(0.882)PT(0.008)R;SLGSASPGPGQPPLS(0.114)S(0.773)PT(0.114)R 180.32 6.2198e-37 34080000.0 54175.0 115110.0 120231.0 135925.0 144210.0 93777.0 94557.0 130231.0 97162.0 92343.0 True False 71401.52308999802 152317.0564012629 118636.65838246005 104589.59127031593 124188.93074579554 87913.10936545258 102972.38981881873 110106.79136066542 102297.78495984557 89110.09967702157 0.8012730694813712 1.70931305153214 1.3313491827801462 1.1737119770867677 1.3936571858399525 0.9865672879291183 1.1555636251338608 1.2356263965560144 1.1479931604904785 1.0 16.443301334621033 -6.752498422082533 24.99834405704326 1.1230275809671488 1.3023493049329622 0.13164889454777884 0.22148142702422888 396.9891093320138 1109954.9330722226 0.0709982983720837 0.07001145204188304 1.768078641663751e-07 6.752498422082533 0.17932172396581336 SLGSASPGPGQPPLSS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLGSASPGPGQPPLSSPTR 19 0 Q9C0B5;Q9C0B5-2 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5 1 SLGSASPGPGQPPLS(0.072)S(0.923)PT(0.005)R;SLGSASPGPGQPPLS(0.031)S(0.901)PT(0.068)R;SLGSASPGPGQPPLS(0.214)S(0.785)PT(0.002)R;SLGSASPGPGQPPLS(0.025)S(0.974)PT(0.001)R 269.99 8.038399999999999e-79 67321600.0 164260.0 168212.0 201462.0 151922.0 354536.0 171834.0 151485.0 179017.0 188883.0 168537.0 True False 192065.97371711762 184910.97568562033 206265.61812889014 143410.3028777693 285067.2158579713 162822.7225435315 137135.24414357523 174317.9934341903 191645.05654347074 199091.42396184232 0.9647124416264601 0.928774188289799 1.0360346720329994 0.7203238593805789 1.4318407603162606 0.8178289114790699 0.6888053810387054 0.8755675657209622 0.9625982512446205 1.0 17.603071551476155 SLGSASPGPGQPPLSS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 2 SLGSASPGPGQPPLSSPTR 19 0 Q9C0B5;Q9C0B5-2 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5 1 SLGSASPGPGQPPLS(0.08)S(0.916)PT(0.004)R;SLGSASPGPGQPPLS(0.227)S(0.773)PTR 282.97 7.412099999999999e-106 62377000.0 259096.0 302060.0 127982.0 72872.0 128641.0 95949.0 73780.0 64716.0 178215.0 47283.0 True False 255401.24352761323 301360.598628511 117459.81398480645 78231.2499738659 121074.58929793692 91845.48493804343 77599.96739168736 67722.94161737333 158142.5500128526 55455.80354936281 4.605491710173728 5.43424816413058 2.118079740387353 1.4106954541598158 2.183262734443383 1.6561924822942853 1.399311928148573 1.2212056679891257 2.851686205792426 1.0 15.759050828462282 -5.31490775456381 5.1354926252907 1.705853974702605 5.026491096011436 0.8573152190406566 0.5379634641330538 0.059427178402916 3.4872925252909894 0.13490214309262386 0.2986605995854809 4.842752181536551e-06 5.31490775456381 3.320637121308831 SLGSVQAPS(ph)YGAR ddPTM_PC-9_AZD4547_30min_R2 2 SLGSVQAPSYGAR 13 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 SLGS(0.002)VQAPS(0.998)YGAR;SLGSVQAPS(1)YGAR 113.67 0.00031869 802390000.0 14580.4 24000.0 34361.0 22325.4 21106.7 27062.6 31976.0 33880.0 24878.0 19820.0 True False 19216.66390884 31757.530654420178 33905.35068892144 17178.62395399162 18176.399033161913 25370.37134386361 34821.80205428001 28644.624484948672 26193.000290556378 19126.107832738493 1.0047346839667244 1.6604282968676072 1.7727261074459206 0.8981766757890317 0.9503448998676591 1.3264785269293893 1.8206423574939237 1.4976713890484905 1.369489313749521 1.0 14.223255694335617 -7.018619583876828 24.629176481095453 1.479157243951629 1.2733693175800433 0.04093744450386827 0.32787563068821174 1882.052656606565 2489492.1906489893 0.13056309875684985 0.10302292833671704 9.580328836640714e-08 7.018619583876828 -0.2057879263715856 SLGSVQAPS(ph)YGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLGSVQAPSYGAR 13 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.092)LGS(0.198)VQAPS(0.71)YGAR;SLGS(0.003)VQAPS(0.951)Y(0.046)GAR;S(0.019)LGS(0.005)VQAPS(0.975)Y(0.001)GAR 155.14 0.00018071 642096000.0 152594.0 126035.0 153377.0 166795.0 161024.0 131929.5 119417.0 119871.7 115578.0 119574.4 True False 178425.15033112076 138546.9218637029 157034.08936551138 157450.0169066861 129472.5031204556 125010.88477138877 108104.9572557895 116725.19488956494 117268.10959790609 141252.29216957014 1.2631664066514792 0.9808472466937422 1.1117277245808908 1.1146722965576443 0.9166046166884628 0.8850184506833777 0.7653324105070944 0.8263596512079182 0.8302032327880982 1.0 17.10791475346793 -6.39957510216973 2.407397427932456 0.8442155455049118 1.11086035669648 0.666699162932083 0.08565304507303496 0.1735509432353212 1.9707922858065523 0.028344706865701383 0.03288714157942176 3.984968546376765e-07 6.39957510216973 0.26664481119156824 SLGSVQAPS(ph)YGAR ddPTM_PC-9_Lapatinib_30min_R1 2 SLGSVQAPSYGAR 13 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 SLGS(0.002)VQAPS(0.98)Y(0.019)GAR;SLGSVQAPS(1)YGAR 119.77 0.00022279 729930000.0 11793.3 26484.7 22276.4 17042.3 26473.0 19124.9 29780.0 26387.0 21973.6 17333.2 True False 11625.125379373647 26423.37630436511 20444.92038139072 18295.647593446207 24915.910187920537 18306.972609319375 31321.862685340904 27613.036350479473 19498.70177573392 20329.220524962773 0.5718431439660392 1.2997732142223144 1.0056913080501968 0.8999679830803404 1.2256205375570426 0.9005250637544008 1.5407311188778725 1.3582929220809383 0.9591465522148752 1.0 14.311267279123172 -7.223251088556648 24.999521583885407 1.2444007959151402 1.0064234874187998 0.1708761398238905 0.24236217044391892 934.8448725545248 611986.1981091618 0.08947447959577232 0.06930518560109067 5.980657217339414e-08 7.223251088556648 -0.23797730849634036 SLGSVQAPSYGAR ddPTM_PC-9_Lapatinib_30min_R1 2 SLGSVQAPSYGAR 13 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ; 163.45 0.0012992000000000001 267800000.0 211056.0 235660.0 252246.0 210471.0 240628.0 239993.0 269218.0 244788.0 213729.0 212464.0 False True 208046.30273706978 235114.3437489068 231507.30757771825 225949.73945067386 226474.73413285016 229729.05884100744 283156.79074620904 256161.7441225289 189656.5893538533 249188.11930951572 0.834896556519439 0.9435214824863783 0.9290463294125343 0.906743628375085 0.9088504490518935 0.9219101595917651 1.136317379539676 1.0279853824184582 0.7610980406264133 1.0 17.926875760207075 -7.029001569091402 24.893788595328896 0.990172521654015 0.9089623314779026 0.13560625743738008 0.090800994040558 1336.2973927984515 1147020.4242126471 0.034950847970904794 0.027123851397372584 9.354022945643196e-08 7.029001569091402 -0.08121019017611242 SLGSVQAPSYGARPVS(ph)SAASVYAGAGGSGSR ddPTM_PC-9_AZD4547_30min_R2 2 SLGSVQAPSYGARPVSSAASVYAGAGGSGSR 31 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 SLGSVQAPS(0.001)YGARPVS(0.415)S(0.415)AAS(0.152)VY(0.017)AGAGGSGSR;SLGSVQAPS(0.01)Y(0.009)GARPVS(0.808)S(0.139)AAS(0.025)VY(0.009)AGAGGSGSR 114.03 2.4244e-17 274138000.0 83106.0 27463.0 135962.0 261810.0 152771.0 70648.0 87095.0 80665.0 55766.0 94198.0 True False 109531.97928781483 36339.877681764236 134159.05504400723 201453.74942417827 131561.3836694123 66230.36939175375 94846.28627462823 68200.07774729584 58713.676911454626 90900.1566916398 1.2049701922888834 0.3997779432332536 1.4758946510853044 2.2162090446947076 1.4473174575012824 0.72860566804551 1.0434116917573077 0.7502745894998912 0.6459139241159811 1.0 16.471995160856146 -6.761000106795966 24.99601882127669 0.8311439554808933 1.3513550105928869 0.26667306112305456 0.4271478834509667 19.005443293740193 1081498.401905479 0.16327061856389702 0.15385370380144886 1.733803571399999e-07 6.761000106795966 0.5202110551119936 SLGSVQAPSYGARPVS(ph)SAASVYAGAGGSGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLGSVQAPSYGARPVSSAASVYAGAGGSGSR 31 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 SLGSVQAPS(0.018)Y(0.017)GARPVS(0.658)S(0.134)AAS(0.134)VY(0.036)AGAGGS(0.001)GS(0.001)R;SLGS(0.001)VQAPS(0.01)Y(0.008)GARPVS(0.792)S(0.108)AAS(0.059)VY(0.022)AGAGGS(0.001)GS(0.001)R;SLGSVQAPS(0.023)Y(0.021)GARPVS(0.397)S(0.122)AAS(0.285)VY(0.143)AGAGGS(0.006)GS(0.003)R 66.738 4.6865e-05 97203000.0 77000.0 38963.3 63212.4 90627.0 102383.0 108410.0 97090.0 133573.0 107054.0 64355.7 True False 90034.57918067735 42831.31892452102 64719.623350362 85549.46300669815 82321.78611251489 102724.78875510214 87892.93232927141 130066.85028229178 108619.4622237296 76022.87897055918 1.184308992238302 0.5634003803132475 0.8513177115460926 1.1253120661193095 1.082855414412746 1.3512351826991926 1.1561379090011714 1.7108908797397928 1.4287733336933197 1.0 16.214146040343934 -6.3699679614629945 1.1108050056627172 1.3846345325165035 0.8402811833657847 0.4042465054169153 0.23087784105769243 0.4316253323199355 1.1163331453305687 0.10150313912729725 0.13584905724291652 4.2661098935532404e-07 6.3699679614629945 -0.5443533491507188 SLGSVQAPSYGARPVS(ph)SAASVYAGAGGSGSR ddPTM_PC-9_Lapatinib_30min_R1 2 SLGSVQAPSYGARPVSSAASVYAGAGGSGSR 31 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 SLGSVQAPS(0.02)Y(0.017)GARPVS(0.7)S(0.206)AAS(0.037)VY(0.019)AGAGGSGSR;SLGSVQAPS(0.05)Y(0.044)GARPVS(0.512)S(0.215)AAS(0.119)VY(0.045)AGAGGS(0.007)GS(0.008)R 72.051 1.3240999999999999e-05 204728000.0 69024.0 33717.0 50077.0 35753.0 40628.4 41414.0 23414.7 22770.9 32119.9 19873.1 True False 68039.70510254853 33638.930358066325 45959.8623628101 38382.39488851165 38238.717390507714 39642.81976074924 24626.998596993002 23828.919143257408 28502.218624458248 23308.138855758767 2.9191393411378224 1.4432267872711388 1.9718375047973744 1.6467378680914486 1.6405736050890238 1.700814466829669 1.056583657296532 1.0223432806334931 1.2228440374773284 1.0 14.50854619007522 -1.522878745280344 0.2523389921624357 0.9823730254275601 10.64195951126446 0.6923901595169495 0.3055011406067189 30.282148050626315 0.41327663295382877 0.388195488321926 124.53593412623367 0.02999999999999955 1.522878745280344 9.6595864858369 SLGSVQAPSYGARPVSS(ph)AASVYAGAGGSGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLGSVQAPSYGARPVSSAASVYAGAGGSGSR 31 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 SLGSVQAPS(0.014)Y(0.011)GARPVS(0.177)S(0.452)AAS(0.245)VY(0.1)AGAGGS(0.001)GSR 89.583 1.8357000000000002e-09 147930000.0 13195.0 2973.2 10004.0 28559.0 13652.0 37210.0 21863.0 42361.0 27441.0 16422.0 True False 15428.652886870614 3268.359646805735 10242.533300381278 26958.931819527254 10976.988601701994 35258.64209553872 19791.978365587245 41249.068635189564 27842.272711728358 19399.178603519533 0.7953250600039036 0.16847928015945823 0.5279879890648054 1.3896945004999428 0.5658481127500148 1.8175327325014605 1.0202482677280185 2.126330680192092 1.4352294641319 1.0 14.24370794692491 -6.169403193804256 0.915004724286748 1.5265394442731397 0.42396108651164205 0.41765025502427866 0.4417917137927243 0.5290363152887273 0.9308417487759025 0.20159426518788498 0.3644321272935246 6.770126852781202e-07 6.169403193804256 -1.1025783577614976 SLGSVQAPSYGARPVSS(ph)AASVYAGAGGSGSR ddPTM_PC-9_Lapatinib_30min_R1 1 SLGSVQAPSYGARPVSSAASVYAGAGGSGSR 31 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 SLGSVQAPS(0.158)Y(0.145)GARPVS(0.158)S(0.188)AAS(0.162)VY(0.054)AGAGGS(0.06)GS(0.074)R 48.305 0.006648 48060000.0 8157.4 4427.6 6257.8 2412.4 4043.6 4018.6 1812.4 4227.4 5429.7 4162.3 True False 8041.073980116051 4417.3481642309325 5743.3078398065545 2589.815943530488 3805.7633980234755 3846.7338458141408 1906.2372038586914 4423.820436882442 4818.150008724219 4881.748009083875 1.6471710471645309 0.9048701727355047 1.1764859286303806 0.5305099605123823 0.7795903006344806 0.7879828779888275 0.390482507559095 0.9061959832114789 0.9869722893845987 1.0 12.25318211123797 -2.026371140242162 0.9464390999669426 0.7675795146284106 199.9999999585944 0.5683389464169295 0.21534440350201647 283.77313116468764 1.4882470804052093 0.06950525532668242 121077.07917759291 0.009410850184759345 2.026371140242162 199.232420443966 SLGSVQAPSYGARPVSSAAS(ph)VYAGAGGSGSR ddPTM_PC-9_AZD4547_30min_R2 2 SLGSVQAPSYGARPVSSAASVYAGAGGSGSR 31 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 SLGSVQAPS(0.001)Y(0.001)GARPVS(0.312)S(0.082)AAS(0.536)VY(0.068)AGAGGSGSR;SLGSVQAPS(0.006)Y(0.006)GARPVS(0.046)S(0.132)AAS(0.399)VY(0.343)AGAGGS(0.034)GS(0.034)R 93.679 7.63e-11 296547000.0 84323.0 25254.0 67382.0 257722.0 149997.0 70916.0 102424.0 73447.0 52280.5 82129.0 True False 111135.95997264214 33416.86163111362 66488.47065338325 198308.17466520745 129172.50568668645 66481.61130938755 111539.5375784207 62097.45379415661 55043.94049724387 79253.68870812196 1.402281228599179 0.4216442436412306 0.8389321902510952 2.502194887048642 1.6298611180409168 0.8388456410430077 1.4073734534830562 0.783527616270974 0.6945284363982284 1.0 16.274190463786596 -7.769273699152603 24.41671557788754 0.804270762256494 1.2828798623645918 0.13831408234691833 0.5313799892370951 301.0382901826538 938203.0545372013 0.3086113823388613 0.15270052725355088 1.7010861195220264e-08 7.769273699152603 0.4786091001080979 SLGSVQAPSYGARPVSSAAS(ph)VYAGAGGSGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLGSVQAPSYGARPVSSAASVYAGAGGSGSR 31 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 SLGSVQAPS(0.007)Y(0.006)GARPVS(0.062)S(0.062)AAS(0.583)VY(0.278)AGAGGS(0.001)GSR;SLGS(0.001)VQAPS(0.015)Y(0.014)GARPVS(0.203)S(0.145)AAS(0.489)VY(0.094)AGAGGS(0.018)GS(0.021)R 89.583 1.8357000000000002e-09 186267000.0 20701.6 0.0 11614.4 26856.6 14829.0 47542.0 18586.8 55843.0 38425.0 6676.8 True False 24205.97200476247 0.0 11891.331343857286 25351.91177227198 11923.363900867198 45048.81382709223 16826.123747221176 54377.180420549346 38986.89293204195 7887.250986480284 3.068999838632557 0.0 1.507664884031266 3.2142899745080085 1.5117261922189755 5.711598870672611 2.1333318511181165 6.8943134323680715 4.9430267908134615 1.0 12.945306837214831 -6.519486421689749 1.4411640025152803 4.399122251037265 1.5599286063097564 0.22426266770060332 1.8587488875192104 0.5055641481865668 2.155116964023849 0.7389090403023462 0.8216760531067486 3.023525100195212e-07 6.519486421689749 -2.8391936447275086 SLGSVQAPSYGARPVSSAAS(ph)VYAGAGGSGSR ddPTM_PC-9_Lapatinib_30min_R1 2 SLGSVQAPSYGARPVSSAASVYAGAGGSGSR 31 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 SLGSVQAPS(0.003)Y(0.002)GARPVS(0.035)S(0.129)AAS(0.639)VY(0.192)AGAGGSGSR;SLGS(0.003)VQAPS(0.021)Y(0.02)GARPVS(0.133)S(0.133)AAS(0.497)VY(0.114)AGAGGS(0.057)GS(0.023)R 90.12700000000001 1.6019e-09 207732000.0 147420.8 37974.5 51866.7 47714.6 26631.2 41475.9 18930.7 7056.62 40704.2 11943.8 True False 145318.55235833643 37886.57237839633 47602.42013725184 51223.690855239554 25064.805174953697 39702.072442045195 19910.83901737351 7384.49632665784 36119.6643617718 14008.26991588687 10.373768725967345 2.7045861199054224 3.398165542431876 3.6566750328780024 1.7892862805654206 2.8341881388949264 1.4213631759616865 0.5271526299106383 2.578452912362022 1.0 13.773991167017211 -3.4576241053447236 1.2784174535035595 2.0400857433964044 199.99999999988995 0.8576248415952746 0.993447549750274 13.292481266152913 1.1274678251303198 0.2997833804336713 6926.425665268766 0.0003486389417482325 3.4576241053447236 197.95991425649353 SLGTADVHFER ddPTM_PC-9_AZD4547_30min_R2 2 SLGTADVHFER 11 0 E9PB61;Q86V81 E9PB61 ALYREF THO complex subunit 4 0 ; 131.17 0.00014445 24669000.0 124515.0 129784.0 190892.0 259520.0 190538.0 173890.0 132146.0 188857.0 137944.0 175011.0 False True 164108.17992710878 171734.13993555287 188360.64735338296 199691.67354403067 164085.0876252855 163016.6308109511 143906.7379992773 159673.49015212394 145235.43822174246 168883.91815920244 0.9717217702896276 1.0168768098669028 1.115326132922972 1.1824197100625446 0.9715850355307768 0.9652584602950743 0.8521044488298773 0.945462965879344 0.8599719843356122 1.0 17.365672429594525 -6.570090550912819 3.1803902180090606 0.9162723954727264 1.0714179100136108 0.5044421718938152 0.06778086473816847 0.20768360359271837 4.3116924081887 0.024286442280488433 0.02506479998819169 2.690973674239e-07 6.570090550912819 0.15514551454088432 SLGTADVHFER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLGTADVHFER 11 0 E9PB61;Q86V81 E9PB61 ALYREF THO complex subunit 4 0 ; 120.57 0.00071594 15156100.0 99155.0 85602.0 106899.0 119075.0 135737.0 118680.0 114374.0 110750.0 106024.0 83280.0 False True 115939.9830994813 94100.0008360908 109447.87757671534 112403.61379635849 109140.30924620738 112456.21187580033 103539.666723948 107842.92984932466 107574.40042229829 98378.00475588255 1.1785152929984446 0.9565146301715786 1.1125238598638165 1.142568545431262 1.1093974666088287 1.1431031982692856 1.0524676423441777 1.0962097688088774 1.0934802010798643 1.0 16.586048175025574 -9.9126406935894 0.7406810464850998 0.9937669545247908 1.0976251033754219 0.21020909122453557 0.05735844006025646 20.778838171699935 8.895077435216887 0.4320915883158517 0.019779027343473653 1.2228109143222822e-10 9.9126406935894 0.10385814885063105 SLGTADVHFER ddPTM_PC-9_Lapatinib_30min_R1 2 SLGTADVHFER 11 0 E9PB61;Q86V81 E9PB61 ALYREF THO complex subunit 4 0 ; 162.68 0.00029894 21575000.0 200773.0 182243.0 204140.0 156278.0 189140.0 210760.0 180028.0 185362.0 191680.0 142187.0 False True 197909.94020274113 181821.02753047695 187356.3972031885 167771.2054481254 178015.1570635475 201746.286105556 189348.9689562306 193974.59521724962 170090.97992011672 166763.83349773148 1.1867677544449908 1.0902905247314927 1.1234833912938151 1.0060407099624968 1.0674686071303887 1.2097724181202658 1.1354318558454484 1.163169442371258 1.019951246937667 1.0 17.34744691615125 -8.369003092950226 5.6816442617562 1.0026235712586267 1.119143759531176 0.3932792665489123 0.05604134044648928 0.2603375669961916 11.071627611254764 0.0571462451058818 0.01486563122684526 4.27559841153154e-09 8.369003092950226 0.11652018827254929 SLGVLPFTLNS(ph)GSPEK ddPTM_PC-9_Lapatinib_30min_R1 2 SLGVLPFTLNSGSPEK 16 0 P42695 P42695 NCAPD3 Condensin-2 complex subunit D3 1 SLGVLPFTLNS(0.703)GS(0.297)PEK;SLGVLPFT(0.001)LNS(0.653)GS(0.345)PEK 177.07 1.0932e-06 144870000.0 398249.43 474282.1 445598.9 426298.4 410255.2 479363.3 559420.3 430997.5 417628.7 328922.1 True False 392570.3200981994 473183.92893725616 408963.4785034961 457649.8064257739 386124.7957287568 458862.0491094308 588384.3458694504 451023.2172837305 370590.95798082434 385775.846723852 1.0176124903413435 1.2265773841356458 1.0601064892386651 1.1863101599343286 1.0009045382386383 1.1894525098091373 1.5251974711901304 1.1691328555532514 0.9606380521953792 1.0 18.557403294074376 -5.788367518526815 24.608413990744687 1.1658164215373725 1.1139465321836053 0.006246736157308863 0.1586815348985293 1010.6983229477298 923627.7457363778 0.047168516607061596 0.0699838143148074 1.627917836023168e-06 5.788367518526815 -0.05186988935376724 SLGVLPFTLNSGS(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 2 SLGVLPFTLNSGSPEK 16 0 P42695 P42695 NCAPD3 Condensin-2 complex subunit D3 1 SLGVLPFTLNS(0.013)GS(0.987)PEK;SLGVLPFTLNS(0.001)GS(0.999)PEK 243.37 7.829e-47 171670000.0 89941.0 84166.0 94797.0 85487.0 89461.0 94782.0 102735.0 92585.0 89212.0 105388.0 True False 118540.3671109833 111371.01354416378 93539.92984074063 65779.29291098403 77040.88435926517 88855.26655657907 111878.21597593377 78278.11564164622 93927.56419009234 101698.39819761047 1.1656070224493325 1.0951107934636142 0.919777808682718 0.6468075611492728 0.7575427511608077 0.8737135307079678 1.1000981132322543 0.7697084421088302 0.9235894159078238 1.0 16.63393743061784 -5.263570161577155 3.450222572252974 0.8586616353759234 1.1446369818854127 0.42146100540824716 0.12153739168911264 0.223207355777193 5.678573605626853 0.03403779573218266 0.09370871907508581 5.450418354313598e-06 5.263570161577155 0.2859753465094893 SLGVLPFTLNSGS(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLGVLPFTLNSGSPEK 16 0 P42695 P42695 NCAPD3 Condensin-2 complex subunit D3 1 SLGVLPFTLNS(0.094)GS(0.906)PEK 112.57 0.00033174 1268200.0 6953.8 7638.4 8085.3 9703.6 10652.0 6531.1 9059.0 9116.6 8481.0 7252.1 True False 8130.940996189528 8396.689871573026 8278.084215670999 9159.938751495662 8564.817066021806 6188.5976186555445 8200.865938519632 8877.298909836145 8605.018580524335 8566.848322407988 0.9491169552893479 0.980137566998836 0.9662928423768541 1.069230877770574 0.9997628933874235 0.7223890730583217 0.9572792268387582 1.036238599744567 1.0044555776733557 1.0 13.064548830199808 -7.697800529152492 7.4650905681350626 1.0150684010231406 0.9485815666472343 0.11017381925922265 0.08395431202412366 0.5610015412232885 55.497429768314596 0.0434672725397712 0.024807066102513695 2.0053928900202644e-08 7.697800529152492 -0.0664868343759063 SLGVLPFTLNSGS(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 1 SLGVLPFTLNSGSPEK 16 0 P42695 P42695 NCAPD3 Condensin-2 complex subunit D3 1 SLGVLPFTLNS(0.083)GS(0.917)PEK 170.47 2.8748000000000003e-05 68450000.0 29326.0 43120.0 31369.0 36217.0 35947.0 34761.0 38249.0 43061.0 34360.0 28389.0 True False 28907.805862270263 43020.15828928489 28789.96190784171 38880.51899637031 33832.6681345212 33274.35306184875 40229.34606620563 45061.77126190915 30490.014973159512 33296.00082403529 0.8682065457363476 1.2920518147702005 0.864667263194539 1.1677233912219194 1.016118071155816 0.999349838970123 1.2082335737199221 1.3533688775434116 0.9157260397215563 1.0 15.023061285440273 -7.256407768194947 24.746107209378785 1.1487795280153996 1.0438596065047772 0.04761041365159391 0.16263366333732943 938.660985145547 4616461.089511882 0.05992699473004259 0.04498140514508549 5.5410520764204757e-08 7.256407768194947 -0.10491992151062246 SLGVSNFNR ddPTM_PC-9_AZD4547_30min_R2 1 SLGVSNFNR 9 0 P51857-2;P51857 P51857-2 AKR1D1 3-oxo-5-beta-steroid 4-dehydrogenase 0 122.28 0.007214399999999999 17806000.0 21228.0 31779.0 38499.0 38991.0 33047.0 34719.0 29619.0 43219.0 32545.0 28913.0 False True 27978.062430170306 42050.940277784124 37988.478105200265 30002.227354944913 28458.99448274254 32548.015441517116 32255.033620394028 36540.49662381931 34265.262258065675 27900.764670432287 1.0027704530915575 1.507160852919111 1.3615568803911093 1.0753191788589092 1.0200076886387932 1.1665635628979636 1.156062710158484 1.309659324948285 1.2281119411174468 1.0 14.768017041787534 -5.756808605723468 24.99955100606141 1.1466444350039149 1.3121625582619092 0.18317392382753417 0.14577814789594587 187.70652516388196 1013330.5763085956 0.04029406335555457 0.06694342093557681 1.7506180188248796e-06 5.756808605723468 0.1655181232579943 SLGVSNFNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLGVSNFNR 9 0 P51857-2;P51857 P51857-2 AKR1D1 3-oxo-5-beta-steroid 4-dehydrogenase 0 ; 107.69 0.011451000000000001 17751200.0 38463.0 42269.0 52850.0 51655.0 51236.0 46250.0 48363.0 39743.0 35690.0 32738.0 False True 44974.02622112199 46465.18697391082 54110.14443474113 48760.93781776956 41196.673600703456 43824.568581528256 43781.706522201705 38699.78836118927 36211.89873115358 38673.1402461346 1.1629266704199737 1.2014847172529528 1.399166038505225 1.2608476453536313 1.0652528690069611 1.1332042937968696 1.1320959778169994 1.000689060026806 0.9363578571764153 1.0 15.239044295084376 -7.113057839706902 0.7845626957078072 0.9681984128650268 1.256233202038813 0.6494008182059208 0.07744816654914442 0.442163518752902 0.5527725337112069 0.0660967584770282 0.04563224102522164 7.708008063240528e-08 7.113057839706902 0.2880347891737861 SLGVSNFNR ddPTM_PC-9_Lapatinib_30min_R1 2 SLGVSNFNR 9 0 P51857-2;P51857 P51857-2 AKR1D1 3-oxo-5-beta-steroid 4-dehydrogenase 0 ; 126.24 0.006453699999999999 84391000.0 85448.0 97429.0 108546.0 81980.0 74927.0 84921.0 94925.0 76974.0 84740.0 84092.0 False True 84229.49585075583 97203.40913651977 99621.76687967712 88009.08267726307 70519.94117214982 81289.12679051967 99839.75202840775 80550.49304740259 75195.68884824033 98627.1901544532 0.8540190156370658 0.9855640111443533 1.0100842042003466 0.892340971485025 0.7150152109343623 0.8242060497031134 1.0122943974380254 0.8167169004942557 0.7624235135410588 1.0 16.58969781208883 -5.994371877985078 24.003685956219623 0.8478428108391428 0.9530826221414609 0.1627576145916373 0.09527911633628196 154.6720333718593 659651.2145049816 0.027338408474046266 0.040391514973543326 1.0130435645829225e-06 5.994371877985078 0.10523981130231808 SLGVSNFNRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLGVSNFNRR 10 1 P51857-2;P51857 P51857-2 AKR1D1 3-oxo-5-beta-steroid 4-dehydrogenase 0 72.096 0.019903 5600100.0 20763.0 9702.9 16591.0 28280.0 30098.0 31900.0 22831.0 29343.0 28179.0 21568.0 False True 24277.765812057183 10666.139787767854 16986.592361717892 26695.563284997046 24200.512960300814 30227.107843259484 20668.282397874136 28572.777341478402 28591.064565569544 25478.107667805947 0.9528873230539994 0.4186394031628005 0.6667132654903604 1.0477843815194121 0.94985519630567 1.1863953256408581 0.8112173269442028 1.121463874555443 1.122181636813519 1.0 14.636970508020656 -5.754893117806203 10.315066257675348 1.0328107336948271 0.6529935159441828 0.5202066756700201 0.15548710096034213 0.11519206671938452 146.04423930443113 0.04087915778884134 0.06696237136566935 1.7583563015993863e-06 5.754893117806203 -0.37981721775064436 SLGVSNFNRR ddPTM_PC-9_Lapatinib_30min_R1 1 SLGVSNFNRR 10 1 P51857-2;P51857 P51857-2 AKR1D1 3-oxo-5-beta-steroid 4-dehydrogenase 0 80.916 0.010757 5124900.0 39081.0 16919.0 17416.0 16646.0 26651.0 18694.0 14481.0 12254.0 20528.0 12039.0 False True 38523.69777342236 16879.82509500027 15984.123707704146 17870.20236942817 25083.440577881982 17894.50119784242 15230.755323922818 12823.365575426373 18215.920470576773 14119.925109040845 2.728321678473778 1.1954613756550514 1.1320260967580964 1.2656017812719178 1.7764570551313554 1.2673226705986387 1.0786711123680621 0.9081751833949673 1.2900861959185113 1.0 13.785444816239144 -4.760778801187269 24.995811297341724 1.2240517297071891 2.7283234086866286 0.8072142650266476 0.22215082377120138 7.279722211668 275254.5065176202 0.05960539253400608 0.3457211393518003 1.7346872994909818e-05 4.760778801187269 1.5042716789794395 SLGYAYVNFQQPADAER ddPTM_PC-9_Lapatinib_30min_R1 2 SLGYAYVNFQQPADAER 17 0 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YBN4;Q13310-3;E5RGH3;Q13310-2;Q13310;B1ANR0;E5RH24;E5RJB9;B1ANR1;E5RHG7 A0A087WTT1 PABPC1;PABPC4 Polyadenylate-binding protein;Polyadenylate-binding protein 1;Polyadenylate-binding protein 4 0 ; 204.67 1.5053e-16 11350800.0 40489.0 30786.0 38470.0 36497.0 36669.0 41443.0 36413.0 38749.0 35773.0 33257.0 False True 39911.619435226756 30714.71690848621 35307.14509849438 39181.11113042291 34512.20151402781 39670.57949835154 38298.286969822635 40549.420000179205 31743.868033609855 39005.42813783301 1.0232324407308528 0.7874472445206853 0.9051854263393789 1.0045040652282828 0.8848050941031196 1.017052789631435 0.9818706984701832 1.039584025507686 0.8138320625897741 1.0 15.251387288206441 -5.619368684996495 7.324559495874358 0.9642826189207565 0.8909694299795599 0.08723968681702321 0.08296686986257112 0.4376000092322564 28.55778067622483 0.021399731356328684 0.03723571477451081 2.4023225338593274e-06 5.619368684996495 -0.07331318894119665 SLHDALCVIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLHDALCVIR 10 0 E7ENZ3;B7ZAR1;E9PCA1;P48643-2;P48643 E7ENZ3 CCT5 T-complex protein 1 subunit epsilon 0 ; 101.38 0.0030416 2245500.0 7583.6 9004.900000000001 11983.4 12113.900000000001 9122.8 9519.1 9249.7 9778.8 10303.2 6677.2 False True 8867.35369707253 9898.846960689152 12269.12970329758 11435.197456793694 7335.252828567754 9019.901638582172 8373.5014539712 9522.116861495044 10453.86480826062 7887.723503313883 1.1241968222323049 1.2549688077339847 1.5554715753085069 1.4497462356520743 0.9299581590919079 1.1435367422289366 1.0615865845770616 1.2072072325423806 1.3253335774090735 1.0 12.945393264954314 -6.246334493143309 24.974397580341222 1.1207598638091423 1.3545421945689446 0.37764185745225154 0.14722172668692526 947.8479620213036 1567170.2995921818 0.04615549238592707 0.05934589143299814 5.67107651455625e-07 6.246334493143309 0.23378233075980237 SLHDALCVIR ddPTM_PC-9_Lapatinib_30min_R1 2 SLHDALCVIR 10 0 E7ENZ3;B7ZAR1;E9PCA1;P48643-2;P48643 E7ENZ3 CCT5 T-complex protein 1 subunit epsilon 0 ; 150.81 5.280699999999999e-09 0.0 10851.400000000001 9392.4 11872.5 6980.5 9467.2 11995.4 7728.5 7267.8 12488.8 6963.4 False True 10696.657046096956 9370.652474867335 10896.388879175327 7493.8692562653705 8910.35790923134 11482.384704643138 8128.64391415907 7605.488520408337 11082.179831105772 8167.014411852732 1.309738970286739 1.1473779771060242 1.3341948880807009 0.9175775722140969 1.0910177771083394 1.405946423699073 0.9953017717664394 0.9312446552525416 1.356943831888221 1.0 12.995593058208117 -1.5228790102173733 0.5461126536612579 1.1077911499816062 9.42976238072557 0.10457614114746616 0.1691568663865324 330.30312664572665 3.0626463839188873 0.08453092756084284 3219.3347822596907 0.029999981698803514 1.5228790102173733 8.321971230743964 SLHLLK ddPTM_PC-9_AZD4547_30min_R2 1 SLHLLK 6 0 Q16236-3;Q16236-2;Q16236 Q16236-3 NFE2L2 Nuclear factor erythroid 2-related factor 2 0 71.359 0.037674 0.0 35741.0 25407.0 28874.0 43079.0 42925.0 33169.0 24781.0 21673.0 14251.0 20586.0 False True 47105.8945410174 33619.31588903555 28491.111894063557 33147.80211391531 36965.60468943393 31094.937186545718 26986.460992841916 18323.93584599448 15004.278766006875 19865.290405890744 2.371266343382973 1.6923646824244896 1.4342157256163222 1.6686291232916406 1.8608137074337636 1.5652898372593131 1.3584730170790504 0.9224096638708489 0.7553012545720242 1.0 14.277962263540577 -7.501258619691598 1.6072790635679393 0.8442368018654064 1.7684167742432755 0.7376514017703266 0.23515251809440754 0.2118655571911719 1.0605717033681246 0.1595493512461443 0.07848931798331894 3.153126396827006e-08 7.501258619691598 0.9241799723778691 SLHLS(ph)PQEQSASYQDR ddPTM_PC-9_AZD4547_30min_R2 2 SLHLSPQEQSASYQDR 16 0 Q5JW53;Q9H410-4;Q9H410 Q5JW53 DSN1 Kinetochore-associated protein DSN1 homolog 1 S(0.012)LHLS(0.988)PQEQSASYQDR;S(0.002)LHLS(0.998)PQEQSASYQDR 78.902 0.005312300000000001 23860000.0 20538.7 18153.4 67143.0 93043.0 66430.0 73387.0 46099.0 98972.0 57049.0 67197.0 True False 27069.579368501007 24021.13154091465 66252.6399495431 71593.37385002023 57207.341165267324 68798.09928876467 50201.72169440374 83678.15155030524 60064.49367215816 64844.45348317498 0.41745404447775447 0.37044234704125234 1.0217163749669584 1.104078606639755 0.8822241239200322 1.0609712256517905 0.7741868270572972 1.2904442408789365 0.9262857568495498 1.0 15.984695557348962 -5.262127440389902 24.99431866019146 1.0104152448871067 0.3939481443014946 0.7794514666729958 0.1305376673033791 23.43137730316635 851201.170120366 0.03217459054118465 0.07406064225720722 5.468554687977237e-06 5.262127440389902 -0.616467100585612 SLHLS(ph)PQEQSASYQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLHLSPQEQSASYQDR 16 0 Q5JW53;Q9H410-4;Q9H410 Q5JW53 DSN1 Kinetochore-associated protein DSN1 homolog 1 S(0.001)LHLS(0.999)PQEQSASYQDR;S(0.008)LHLS(0.992)PQEQSASYQDR;S(0.002)LHLS(0.998)PQEQSASYQDR;SLHLS(1)PQEQSASYQDR 99.273 0.0010972000000000002 29735200.0 62701.0 95040.0 206704.0 151938.0 202405.0 150284.0 152306.0 117652.0 138488.0 94885.0 True False 73315.04089880064 104474.94310252146 211632.60728928517 143425.40644964197 162745.19322645004 142402.84248013815 137878.47308005014 114563.75966259843 140513.1250064444 112086.89939075308 0.6540910784159756 0.9320887960180332 1.888111888540155 1.2795911674712117 1.4519555283538885 1.2704682104168015 1.2301033736278444 1.0220976785450244 1.2536088139666786 1.0 16.774258141621473 -7.604221138178505 6.103340548134832 1.1044515262508057 1.2701934353354483 0.044872550218183704 0.30804072245028336 0.7624746205255236 44.93177101509813 0.15615737279949338 0.08899040646251836 2.4875903409284728e-08 7.604221138178505 0.1657419090846426 SLHLS(ph)PQEQSASYQDR ddPTM_PC-9_Lapatinib_30min_R1 3 SLHLSPQEQSASYQDR 16 0 Q5JW53;Q9H410-4;Q9H410 Q5JW53 DSN1 Kinetochore-associated protein DSN1 homolog 1 S(0.003)LHLS(0.997)PQEQSASYQDR;S(0.004)LHLS(0.925)PQEQS(0.063)AS(0.008)YQDR;S(0.197)LHLS(0.802)PQEQS(0.001)ASYQDR 126.25 0.00016363 7752600.0 28664.5 33025.4 83175.0 44548.8 73454.4 75740.0 54768.1 68847.0 94558.0 52335.0 True False 28255.738973574495 32948.93171537455 76336.6725647847 47825.06736244035 69133.95660890671 72500.77675856341 57603.72423562858 72045.88295833021 83907.88230011697 61381.03501799596 0.4603333743930899 0.536793354913524 1.2436524171090304 0.7791505527467693 1.1263080948152424 1.1811592414058727 0.9384612725859065 1.1737482585167796 1.3670001210555751 1.0 15.905505352540887 -5.2480478452974495 21.211457104712995 1.0938309256420675 0.4985620407063602 0.701528488129336 0.15717075360368238 55.959135431775145 88632.0382285899 0.03997917215606341 0.10376979116139483 5.648747403380332e-06 5.2480478452974495 -0.5952688849357073 SLHLS(ph)PQEQSASYQDRR ddPTM_PC-9_AZD4547_30min_R2 1 SLHLSPQEQSASYQDRR 17 1 Q5JW53;Q9H410-4;Q9H410 Q5JW53 DSN1 Kinetochore-associated protein DSN1 homolog 1 S(0.046)LHLS(0.947)PQEQS(0.005)AS(0.002)Y(0.001)QDRR 58.07899999999999 0.015918 11251000.0 3574.5 0.0 25347.0 48413.0 27940.0 25303.0 12995.0 33878.0 15165.0 23550.0 True False 4711.116645781221 0.0 25010.882218564417 37252.13082339381 24061.013279505754 23720.799410026422 14151.529825349287 28642.93353899327 15966.590940038888 22725.521668062116 0.20730510456893528 0.0 1.1005636123070428 1.6392200525696636 1.0587661586365475 1.043795594948346 0.6227152904145429 1.2603861841925212 0.7025841330840796 1.0 14.472025791649273 -5.26401886754156 24.924155110829727 1.068177750521228 0.10365249550167639 0.6660248653531602 0.268885995221113 116.64614419617739 1127099.9630401947 0.07233180906803917 0.16256493714315737 5.4447899791770275e-06 5.26401886754156 -0.9645252550195516 SLHLS(ph)PQEQSASYQDRR ddPTM_PC-9_Lapatinib_30min_R1 2 SLHLSPQEQSASYQDRR 17 1 Q5JW53;Q9H410-4;Q9H410 Q5JW53 DSN1 Kinetochore-associated protein DSN1 homolog 1 S(0.002)LHLS(0.99)PQEQS(0.005)AS(0.002)Y(0.001)QDRR;S(0.025)LHLS(0.92)PQEQS(0.033)AS(0.014)Y(0.008)QDRR 74.85300000000001 0.0034278 11377500.0 34154.0 23021.0 70250.0 37850.0 41658.0 52234.0 26234.0 29210.0 63969.0 23668.0 True False 33666.9576969235 22967.696288906016 64474.316172842 40633.61526389859 39207.75834277916 50000.073583401136 27592.268156052145 30567.203236347657 56764.13759656694 27758.982264372356 1.212831125301514 0.8273969149936818 2.3226469745467737 1.463800613326172 1.4124350082207766 1.801221424734091 0.993994228364266 1.1011644067217676 2.0448926065067465 1.0 14.760667054488007 -7.260637346423931 24.999876799850938 1.293443195121043 1.5066943387287386 0.05334488968119555 0.4569984897180592 282.0741684697622 8792646.382621799 0.18458336736618322 0.13438819026940774 5.487349897194646e-08 7.260637346423931 0.2132511436076956 SLHPWYGITPT(ph)SSPK ddPTM_PC-9_AZD4547_30min_R2 1 SLHPWYGITPTSSPK 15 0 H0Y6J8;Q8N3F8 H0Y6J8;Q8N3F8 MICALL1 MICAL-like protein 1 1 SLHPWYGITPT(0.348)S(0.326)S(0.326)PK 126.25 5.0616000000000005e-05 22973000.0 27484.0 25282.0 103990.0 178380.0 153870.0 131300.0 78380.0 145400.0 100270.0 147500.0 True False 36223.34029728664 33453.91208354379 102611.02465414116 137257.2469435272 132507.806489533 123089.79024370507 85355.66815782027 122931.77095960849 105570.06749473787 142336.0698955059 0.25449164308020805 0.23503467608810283 0.720906687457871 0.964318089183527 0.930950296624122 0.8647828363820201 0.5996770054174109 0.8636726519838378 0.7416958159111792 1.0 17.118941781173056 -5.323430427933596 3.765702692654347 0.8396975294454685 0.2352101244639341 0.8252827626771735 0.10987495413355812 0.08682772601168542 2.4505642547701894 0.03043749302900653 0.07321676299667576 4.748643560306412e-06 5.323430427933596 -0.6044874049815344 down SLHPWYGITPTS(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLHPWYGITPTSSPK 15 0 H0Y6J8;Q8N3F8 H0Y6J8;Q8N3F8 MICALL1 MICAL-like protein 1 1 SLHPWYGITPT(0.017)S(0.491)S(0.491)PK;SLHPWYGIT(0.002)PT(0.025)S(0.487)S(0.487)PK 139.46 8.277700000000001e-07 21263000.0 54065.0 72663.0 151575.0 192673.0 232495.0 193385.0 171618.0 159038.0 166934.0 127390.0 True False 63217.136667575585 79876.5024269627 155189.12285138847 181878.15646429398 186939.27372932248 183243.55016516402 155361.10063327762 154863.42101468975 169375.09394189925 150484.79858131454 0.42008985135741916 0.5307944933972942 1.0312611261364846 1.2086148114556303 1.2422468946476992 1.2176881113087863 1.0324039510829937 1.0290967757185736 1.1255295919499626 1.0 17.199258233056277 -5.261349673349261 3.1461032438571994 1.1291026239676842 0.43742729356369475 0.911309138676353 0.08002394685731828 0.06938928900625682 1.4038503813782983 0.023622080568946064 0.06819801605275316 5.478356959425953e-06 5.261349673349261 -0.6916753304039895 down SLHPWYGITPTS(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 2 SLHPWYGITPTSSPK 15 0 H0Y6J8;Q8N3F8 H0Y6J8;Q8N3F8 MICALL1 MICAL-like protein 1 1 SLHPWYGIT(0.001)PT(0.095)S(0.521)S(0.383)PK;SLHPWYGITPT(0.211)S(0.394)S(0.394)PK 124.84 1.592e-05 32929000.0 155486.0 99893.0 201379.0 130688.0 155994.0 176251.0 132469.0 128251.0 199324.0 91289.0 True False 153268.74112735942 99661.70389590749 184822.39596541948 140299.23148238752 146818.73961600414 168713.1555911483 139327.59664420513 134210.00966329433 176874.03214522832 107068.18201505349 1.4315059641697312 0.9308246578978554 1.7262121433932067 1.3103727815483206 1.371263963325368 1.5757543690003786 1.3012978647999838 1.2535004063525126 1.6519756739715663 1.0 16.708170285345467 -10.808381826580277 4.408032609930768 0.9997380771952696 1.3860985194003685 0.23185309893807315 0.21503517550153287 0.0005528030429696268 8.960380752230521e-05 0.1990445321140958 0.048241581457807235 1.5545982461774757e-11 10.808381826580277 0.3863604422050989 SLHPWYGITPTSS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 SLHPWYGITPTSSPK 15 0 H0Y6J8;Q8N3F8 H0Y6J8;Q8N3F8 MICALL1 MICAL-like protein 1 1 SLHPWYGITPT(0.007)S(0.187)S(0.806)PK;SLHPWYGITPT(0.012)S(0.228)S(0.76)PK 169.3 0.00018066 28075000.0 21383.4 24110.9 77185.0 169812.0 126487.0 126042.0 73064.0 122195.0 84844.0 120418.0 True False 28182.876397649532 31904.276910652483 76161.47646821696 130664.46696924689 108926.46337454721 118160.57381490519 79566.55445627707 103312.5705117562 89328.6806275411 116202.20247238675 0.2425330656219417 0.2745582805819359 0.6554219700466977 1.124457748555126 0.9373872530551348 1.0168531344574454 0.6847250117757842 0.8890758377519262 0.7687348322745292 1.0 16.82627788798026 -5.4037665442485645 3.188426908357746 0.9079573599585435 0.25191197499695045 0.8241942106566412 0.12040550713685023 0.09936133484181661 1.8792919314748928 0.03397023692475516 0.08067773689152036 3.946694002834267e-06 5.4037665442485645 -0.656045384961593 down SLHRSGS(ph)GSDHK ddPTM_PC-9_AZD4547_30min_R2 1 SLHRSGSGSDHK 12 1 C9JNA8;Q92551 C9JNA8 IP6K1 Inositol hexakisphosphate kinase 1 1 SLHRSGS(0.5)GS(0.5)DHK 69.721 0.01485 13597000.0 0.0 2465.2 33786.0 79395.0 37446.0 17045.0 5933.2 41557.0 8311.6 16020.0 True False 0.0 3262.0276903865247 33337.97556461975 61091.7093905222 32247.26926500976 15979.173455475651 6461.243305868594 35135.32053485869 8750.934207532291 15459.1446761085 0.0 0.21100958421249916 2.1565213511548462 3.9518169129329017 2.0859672343222613 1.033638910189568 0.41795606686146036 2.2727855435080406 0.5660684592114928 1.0 13.916172879557838 -6.7774564945135385 23.79394526298702 1.0976302179311885 1.751960728809158 0.06874180389729012 1.1268374304892785 457.28688048058007 679307.6730594294 0.44336426571577187 0.3924552453075834 1.6693350246127082e-07 6.7774564945135385 0.6543305108779696 SLIEEGGDWDRR ddPTM_PC-9_AZD4547_30min_R2 3 SLIEEGGDWDRR 12 1 Q15008;Q15008-4;C9J0E9;Q15008-3;Q15008-2;H7C531 Q15008 PSMD6 26S proteasome non-ATPase regulatory subunit 6 0 ;; 194.48 1.0158e-05 30500800.0 44594.9 51566.4 74812.0 96771.0 84577.0 77951.0 59896.0 84733.0 54055.8 67963.0 False True 58775.15056845684 68234.23036408731 73819.94399870765 74461.94104704607 72834.94345528827 73076.71164727368 65226.627966073174 71639.4618206364 56913.07923089709 65583.63605632735 0.8961862150792775 1.0404154826896677 1.1255848019055614 1.1353737841417253 1.1105658032246497 1.1142522135325161 0.9945564456056148 1.092337450749268 0.8677938988014718 1.0 16.00104826870058 -8.250170533949582 24.95530544066203 0.9338969462273682 1.068285507181822 0.32020195812279273 0.0753878078977247 733.834186218364 1625114.4286282063 0.053363002001200456 0.019750597107045437 5.621205545715215e-09 8.250170533949582 0.13438856095445384 SLIEEGGDWDRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLIEEGGDWDRR 12 1 Q15008;Q15008-4;C9J0E9;Q15008-3;Q15008-2;H7C531 Q15008 PSMD6 26S proteasome non-ATPase regulatory subunit 6 0 ;; 175.49 0.00066064 19464200.0 50595.0 47483.0 47732.0 57950.0 63180.0 55614.0 61410.0 47578.0 49548.0 46446.0 False True 59159.73420319961 52196.798435785306 48870.111904618076 54703.24937643493 50800.332541424854 52697.50393714833 55592.8002301016 46329.127913057986 50272.545764393304 54866.2921336663 1.0782528197654317 0.9513454692477209 0.8907128585536596 0.9970283620253731 0.9258933047209409 0.9604713912280727 1.0132414287203038 0.8444005620097325 0.9162737959751022 1.0 15.743632461259887 -4.765750906949726 5.269206283428044 0.9410244726804489 1.0853782160623848 0.39289018122229613 0.04992404722318831 0.15852399658053468 12.80605431610876 0.012368292602520288 0.08372595676185136 1.714940643311463e-05 4.765750906949726 0.14435374338193596 SLIEEGGDWDRR ddPTM_PC-9_Lapatinib_30min_R1 3 SLIEEGGDWDRR 12 1 Q15008;Q15008-4;C9J0E9;Q15008-3;Q15008-2;H7C531 Q15008 PSMD6 26S proteasome non-ATPase regulatory subunit 6 0 ;; 182.92 4.1198999999999996e-05 28856100.0 60391.0 58745.0 63583.0 54401.0 67199.0 62232.0 55714.0 59829.0 61756.0 52003.0 False True 59529.813265646975 58608.979561782035 58355.45117747777 58401.83101641605 63246.48693831727 59570.482429877506 58598.59830930436 62608.87375650268 54800.388960490076 60991.64926035813 0.9760321943669544 0.9609344930417429 0.9567777209691922 0.9575381502984648 1.0369696131405433 0.9766989932603065 0.9607642852738999 1.026515506889165 0.8984900330627377 1.0 15.896324107546535 SLIGS(ph)PGR ddPTM_PC-9_AZD4547_30min_R2 3 SLIGSPGR 8 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 SLIGS(1)PGR;SLIGS(1)PGR;SLIGS(1)PGR 87.258 0.011859999999999999 173061000.0 327371.0 332758.0 537610.0 789615.0 726172.0 589203.0 500450.0 766631.0 510728.0 577775.0 True False 431468.16826018976 440315.5160626475 530480.9401318659 607581.4611801403 625355.5524411334 552360.0432670349 544989.0804998891 648165.7943778262 537724.0394081225 557547.2731110243 0.7738683140761619 0.7897366506803227 0.9514546401991484 1.0897398130743843 1.1216188879406581 0.990696340751439 0.9774760038892084 1.1625306510085953 0.9644456449543888 1.0 19.088734607346836 -5.391265437905182 2.804738743371995 1.0483198559470501 0.7751044487203241 0.7350049181088769 0.06212347094737237 0.1304182353076308 1.9484480567546356 0.017022006950017335 0.0432859941195792 4.061949895992305e-06 5.391265437905182 -0.273215407226726 SLIGS(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SLIGSPGR 8 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 SLIGS(1)PGR;SLIGS(1)PGR;SLIGS(1)PGR;SLIGS(1)PGR;SLIGS(1)PGR;SLIGS(1)PGR 94.40899999999999 0.0067423000000000005 210676000.0 374407.0 416345.0 521281.0 579791.0 640353.0 564130.0 548409.0 533472.0 539537.0 444958.0 True False 437786.71022467344 457676.98007175175 533710.3160092022 547307.189977784 514880.4264624728 534546.0297058919 496459.7293826709 519468.92526030616 547426.707921278 525625.3631144102 0.8328873394364393 0.8707284925520832 1.0153815882226218 1.041249582658846 0.9795578040826036 1.0169715299479183 0.9445125068567306 0.9882874033748558 1.0414769650339768 1.0 19.003675366452732 -5.187638752241879 4.280175280436499 1.0020024960793799 0.8429190924865119 0.8258789145127556 0.027987190191747422 0.08681306663337449 3.0175515737099157 0.007525486871884306 0.021816952358943546 6.49174194528249e-06 5.187638752241879 -0.159083403592868 SLIGS(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 2 SLIGSPGR 8 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 SLIGS(1)PGR;SLIGS(1)PGR 94.40899999999999 0.0067423000000000005 135339000.0 576410.0 439790.0 451380.0 375880.0 455590.0 453030.0 415030.0 392800.0 486870.0 342960.0 True False 568190.2876993528 438771.69327561714 414269.27877718804 403523.46909892245 428793.091924403 433654.96296451 436518.2226426132 411050.9219868998 432033.5736316118 402240.1790345256 1.4125647245462847 1.0908201521011056 1.0299052664791848 1.0031903577297452 1.0660125822179447 1.0780995672918294 1.085217850912764 1.0219041841457066 1.0740686687953394 1.0 18.61769767144233 -4.760226702752167 3.8388513639121316 1.0479277410887924 1.4573455175226124 0.9329780458113084 0.0293787857501569 0.06324763498519777 1.651088092657829 0.007572293464729606 0.07566366812613512 1.736893929307259e-05 4.760226702752167 0.40941777643382005 SLIPDIKPLAGQEAVVDLHADDS(ph)RISEDETER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLIPDIKPLAGQEAVVDLHADDSRISEDETER 32 2 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-3;Q9UKV3-2;G3V3B0 S4R3H4 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 SLIPDIKPLAGQEAVVDLHADDS(0.523)RIS(0.428)EDET(0.049)ER 47.286 0.0043560000000000005 5744100.0 15637.0 20999.0 18758.0 15746.0 21257.0 12909.0 17957.0 14099.0 15804.0 13110.0 True False 18284.035255172093 23083.64194244373 19205.26186011116 14863.802669220777 17091.84344465129 12232.029315004282 16255.982962578335 13728.91618912531 16035.103601769435 15486.739221297103 1.1806252429193227 1.490542431985908 1.2401101087632707 0.9597761321363458 1.103643781974896 0.7898389157468992 1.0496711238104521 0.8864949550028928 1.0354086404269165 1.0 13.918745791947915 -5.668583979224729 3.825186151230322 0.9699689750774253 1.3422595139444575 0.6613031584768803 0.10885551034338249 0.11760293554104562 3.2581715619978406 0.0284115150379507 0.05117366587889619 2.144944309308392e-06 5.668583979224729 0.37229053886703223 SLIPDIKPLAGQEAVVDLHADDSRIS(ph)EDETER ddPTM_PC-9_AZD4547_30min_R2 2 SLIPDIKPLAGQEAVVDLHADDSRISEDETER 32 2 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-3;Q9UKV3-2;G3V3B0 S4R3H4 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 SLIPDIKPLAGQEAVVDLHADDS(0.089)RIS(0.853)EDET(0.058)ER;SLIPDIKPLAGQEAVVDLHADDS(0.155)RIS(0.817)EDET(0.027)ER 71.794 6.2323000000000005e-06 25826700.0 50021.0 61678.0 64858.0 61407.0 63756.0 70509.0 63608.0 80581.0 57682.0 57120.0 True False 65926.63749856551 81614.20732097213 63997.94054253566 47250.56487869257 54904.57990866745 66100.0610837272 69268.98877497621 68129.0580171681 60730.952759863096 55120.246185974895 1.1960512163920678 1.4806575254690808 1.1610604990153266 0.8572270290533511 0.9960873491642293 1.1991974937975889 1.2566886682846747 1.2360078688201368 1.101790303239172 1.0 15.750294711178228 -5.503642257224221 24.1839098856066 1.1018179013257872 1.333980627612057 0.3505827699708908 0.1316753021491187 586.8321462966094 737756.984103624 0.037605403469251654 0.07629845393246791 3.1358677790534647e-06 5.503642257224221 0.23216272628626977 SLIPDIKPLAGQEAVVDLHADDSRISEDET(ph)ER ddPTM_PC-9_AZD4547_30min_R2 1 SLIPDIKPLAGQEAVVDLHADDSRISEDETER 32 2 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-3;Q9UKV3-2;G3V3B0 S4R3H4 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 SLIPDIKPLAGQEAVVDLHADDS(0.122)RIS(0.343)EDET(0.535)ER 41.916000000000004 0.021182 15901000.0 10563.0 11846.0 14616.0 9608.7 13499.0 15440.0 12799.0 15418.0 15662.0 17221.0 True False 13921.814275951067 15674.98783884422 14422.182290075252 7393.562667935147 11624.896859701086 14474.534359198833 13938.086205051597 13035.502370393715 16489.861345393274 16618.098031664456 0.8377501594601358 0.943248006419073 0.8678599838919555 0.4449102811794289 0.699532331410657 0.8710102883987545 0.8387293286207416 0.7844160231547321 0.9922833114820458 1.0 14.020467652313243 -8.265461133245566 6.483830382533105 0.9984653878407364 0.7839934351083871 0.29616040367332575 0.12960788455234187 0.19604346218386492 45.90269900824565 0.11719895056681937 0.03614284814918246 5.426738152113989e-09 8.265461133245566 -0.2144719527323492 SLKESEQES(ph)EEEILAQK ddPTM_PC-9_AZD4547_30min_R2 2 SLKESEQESEEEILAQK 17 1 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 S(0.001)LKES(0.002)EQES(0.997)EEEILAQK;SLKES(0.001)EQES(0.999)EEEILAQK 87.06200000000001 0.0013962999999999998 19712600.0 118874.0 107008.0 126226.0 158922.0 138756.0 143669.0 120877.0 140070.0 127400.0 143813.0 True False 156673.45926719744 141596.243344508 124552.16076539668 122284.9882204242 119492.12450290272 134685.35471837685 131634.81883022303 118425.3999883933 134134.1039077452 138778.15064327052 1.1289490351397378 1.0203064581000318 0.8974911409906177 0.8811544731905095 0.8610298087200876 0.9705083551991249 0.9485269707087434 0.8533432636150773 0.9665361822880688 1.0 17.08242092102811 -4.965405295598883 2.6495070158331044 0.9162769779986943 1.1359579727066642 0.6523424245880718 0.04747836786626557 0.19227504480449548 2.3391613429290445 0.012364955450375343 0.07876530827401527 1.0829158353606946e-05 4.965405295598883 0.21968099470796987 SLKESEQES(ph)EEEILAQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLKESEQESEEEILAQK 17 1 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 SLKESEQES(1)EEEILAQK 102.07 0.0022677 0.0 14139.0 14036.0 10368.0 15147.0 16546.0 15225.0 13655.0 12268.0 14251.0 10334.0 True False 16532.453442020746 15429.401319307593 10615.212440858957 14298.362697236575 13303.93007645483 14426.574197919303 12361.499546361149 11945.977999020453 14459.393914756787 12207.472396101017 1.3542896437186374 1.263930879273226 0.8695667781521573 1.1712795436509342 1.0898185672493526 1.1817822502328206 1.0126174481712797 0.9785791531124753 1.1844707442774982 1.0 13.575476895263659 -5.046997911849279 9.71624412307318 1.0675915139502956 1.3320582506623855 0.5219394683043823 0.09652472834616238 0.345836658493328 70.76512576533399 0.023769793819574912 0.06389197323015611 8.974331094786439e-06 5.046997911849279 0.26446673671208987 SLKESEQES(ph)EEEILAQK ddPTM_PC-9_Lapatinib_30min_R1 1 SLKESEQESEEEILAQK 17 1 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 SLKESEQES(1)EEEILAQK 92.289 0.00097735 7913100.0 42756.0 44724.0 42824.0 47087.0 47747.0 38838.0 36051.0 42082.0 38293.0 37318.0 True False 42146.291599509874 44620.44432583436 39303.17602542044 50549.9350576273 44938.615334213755 37176.98927579992 37917.54438110224 44037.283347893965 33980.03909683342 43768.36657689064 0.9629395587671482 1.019467890067289 0.8979813298806589 1.1549422336523125 1.0267373184984472 0.8494031690784888 0.866323039825809 1.0061440897167342 0.7763606859108746 1.0 15.417600923558588 -6.7502021267969745 24.838159849195744 0.8979475044733469 1.0143664922375493 0.2936458470957001 0.08740256080570631 255.13306399855787 563930.0124129304 0.02835028631423998 0.028102226700522034 1.7774519662065037e-07 6.7502021267969745 0.11641898776420234 SLKESEQES(ph)EEEILAQKK ddPTM_PC-9_AZD4547_30min_R2 1 SLKESEQESEEEILAQKK 18 2 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 SLKESEQES(0.999)EEEILAQKK 48.354 0.026639999999999997 8045000.0 33513.0 23937.0 35765.0 50889.0 48443.0 36525.0 25889.0 33246.0 29274.0 32490.0 True False 44169.436886296324 31674.167136452324 35290.73273156412 39157.32727721247 41717.525637047125 34241.08597601925 28193.070846361497 28108.594617078055 30821.363875944502 31352.53498918635 1.4087995405006513 1.0102585691197508 1.1256101857070273 1.2489365625688011 1.3305949790482878 1.0921313376359894 0.8992277930982433 0.8965333944056789 0.9830581127355394 1.0 14.936294475478611 -7.049471277092494 4.39233616060773 0.9391947559425952 1.2096927814490168 0.6053355508685846 0.10603132060493445 0.1583182929716476 6.506054354956111 0.04195964287514154 0.033152663224997624 8.923366340495087e-08 7.049471277092494 0.27049802550642166 SLKPGEELS(ph)PTDENGK ddPTM_PC-9_AZD4547_30min_R2 1 SLKPGEELSPTDENGK 16 1 P42330-2 P42330-2 AKR1C3 Aldo-keto reductase family 1 member C3 1 SLKPGEELS(0.979)PT(0.021)DENGK 76.118 0.020404 0.0 9960.9 17717.0 9347.0 7948.5 8243.9 12067.0 11329.0 13848.0 14802.0 12747.0 True False 13128.259000409058 23443.673775181764 9223.052672778693 6116.096128100835 7099.376785072211 11312.448582412708 12337.259052818923 11708.109795382801 15584.403501118077 12300.731409884842 1.067274665460886 1.9058764063690128 0.7497970946156151 0.4972140212073855 0.5771507846571763 0.9196565802031941 1.0029695504858132 0.9518222457872861 1.2669493367357394 1.0 13.586456481296208 -8.223970806839876 21.475647363205045 1.1334746603805537 0.9555981198811883 0.034761759871099085 0.367474355443739 421.56084502716425 241624.47009349318 0.27388436253166604 0.10350052835628608 5.970754204866568e-09 8.223970806839876 -0.1778765404993654 SLKPGEELS(ph)PTDENGK ddPTM_PC-9_Lapatinib_30min_R1 2 SLKPGEELSPTDENGK 16 1 P42330-2 P42330-2 AKR1C3 Aldo-keto reductase family 1 member C3 1 SLKPGEELS(0.988)PT(0.012)DENGK;SLKPGEELS(0.899)PT(0.101)DENGK 116.69 7.3172e-05 9531400.0 42999.0 88012.0 58873.0 57102.0 86536.0 87336.0 104871.0 116369.0 74295.0 97823.0 True False 42385.82637494916 87808.21362144135 54032.68919635195 61301.47156668795 81446.12261632193 83600.84287015966 110300.70724225609 121775.92856592065 65927.11473896635 114731.57520904596 0.36943471139239853 0.7653360765024879 0.4709487261715184 0.5343034073662284 0.7098841140106681 0.7286646480520751 0.9613805706169671 1.0613985587144565 0.5746204967450701 1.0 16.807902963685656 -6.747134969585628 1.6613104662026752 0.8994394306915487 0.5488757409077476 0.507778286408211 0.15623996629599232 0.3065833027521123 1.7533715601767792 0.06457161411745149 0.05946510963971259 1.7900494578801814e-07 6.747134969585628 -0.35056368978380115 SLKQPLEQNQTIS(ph)PLSTYEESK ddPTM_PC-9_AZD4547_30min_R2 2 SLKQPLEQNQTISPLSTYEESK 22 1 Q9UQR1 Q9UQR1 ZNF148 Zinc finger protein 148 1 SLKQPLEQNQT(0.033)IS(0.966)PLS(0.001)TYEESK;SLKQPLEQNQT(0.013)IS(0.986)PLS(0.001)TYEESK 131.62 7.9458e-07 94455000.0 58031.0 56089.0 72418.0 118592.0 103535.0 80051.0 71004.0 80952.0 52326.0 80131.0 True False 76483.65088021541 74218.67236982401 71457.69000291942 91252.44662813528 89160.95239418867 75045.39831529972 77323.21844702569 68442.72849189972 55091.845534353815 77325.63807997823 0.9891111509627383 0.9598197210226617 0.9241138098208829 1.1801059634807345 1.1530580879522665 0.9705112066153266 0.9999687085291163 0.8851233587120111 0.7124654500409306 1.0 16.238659212823862 -7.763071951851045 3.000006859292226 0.839993154367878 1.0308710047264245 0.346831463365034 0.10061993179663249 0.2795691175935961 5.113043491665542 0.0634520920495208 0.029278744910900715 1.7255519870337118e-08 7.763071951851045 0.19087785035854643 SLKQPLEQNQTIS(ph)PLSTYEESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLKQPLEQNQTISPLSTYEESK 22 1 Q9UQR1 Q9UQR1 ZNF148 Zinc finger protein 148 1 SLKQPLEQNQT(0.026)IS(0.954)PLS(0.01)T(0.004)Y(0.005)EESK;SLKQPLEQNQT(0.003)IS(0.994)PLS(0.002)T(0.001)YEESK 108.5 1.2087e-05 46273000.0 129225.0 91052.0 102628.0 142744.0 183723.0 193413.0 198423.0 192473.0 189385.0 173845.0 True False 151100.24018990927 100091.04081829556 105075.04073885758 134746.51646229177 147723.79701659092 183270.08179587283 179626.93698188371 187420.7876920009 192154.3973437808 205361.72234373743 0.7357760660820496 0.48738898211401693 0.511658353561047 0.6561423176844567 0.7193346224927384 0.8924257145112598 0.8746855788500913 0.9126373968479542 0.9356875037410817 1.0 17.647807775221004 -6.560432603367246 1.4250544353312828 0.9296985555090561 0.5709777406804989 0.8314507184422132 0.06990045233954008 0.15693450077492183 0.6578907634824883 0.029408600141553977 0.03161561961959675 2.7514865653803344e-07 6.560432603367246 -0.3587208148285572 SLKQPLEQNQTIS(ph)PLSTYEESK ddPTM_PC-9_Lapatinib_30min_R1 2 SLKQPLEQNQTISPLSTYEESK 22 1 Q9UQR1 Q9UQR1 ZNF148 Zinc finger protein 148 1 SLKQPLEQNQT(0.002)IS(0.986)PLS(0.009)T(0.002)Y(0.001)EESK;SLKQPLEQNQT(0.026)IS(0.966)PLS(0.006)T(0.001)Y(0.001)EESK 113.5 1.2841e-06 54415000.0 235896.0 127310.0 154173.0 128408.0 147708.0 169719.0 152850.0 157823.0 198278.0 136367.0 True False 232532.07978197164 127015.22151690292 141497.49106499043 137851.5526765311 139020.10584510106 162460.51400431263 160763.82509920615 165156.03274118816 175945.8436800968 159937.85425239446 1.4538902054732947 0.7941535924101054 0.8847029474441761 0.861906978312905 0.8692132734613061 1.0157727497577729 1.005164323672295 1.0326262879615666 1.1000888095099768 1.0 17.28715191218481 -6.976477707828977 24.095265408567993 1.033371579668983 0.9508674857703583 0.020288997484931404 0.17404346731627418 553.1551437279131 566625.8924198003 0.06065358215980098 0.05348788417117959 1.055655688231324e-07 6.976477707828977 -0.08250409389862479 SLLELAR ddPTM_PC-9_AZD4547_30min_R2 1 SLLELAR 7 0 P49321;P49321-3;E9PPR5;P49321-2;E9PI86;E9PPQ8 P49321 NASP Nuclear autoantigenic sperm protein 0 111.65 0.004111699999999999 0.0 18008.0 14086.0 15653.0 22085.0 21400.0 17613.0 17572.0 17571.0 14009.0 16622.0 False True 23734.169410331033 18639.02403325678 15445.430992511481 16993.644459848634 18428.979390888446 16511.656325684515 19135.8739585254 14855.805691411853 14749.48714005967 16040.068839343043 1.4796800218285795 1.162028930171361 0.9629279741385501 1.0594495965108743 1.1489339338548155 1.0294005899266943 1.193004478359156 0.9261684497870464 0.9195401396209824 1.0 13.96939271298603 -4.809193729457419 2.920145940098547 1.0387120977029882 1.5405922313002225 0.7208063597086662 0.08451503918915151 0.2038999027545873 2.5822933809171187 0.022555998063011607 0.23751680127161304 1.551694677823729e-05 4.809193729457419 0.5018801335972343 SLLELAR ddPTM_PC-9_Lapatinib_30min_R1 1 SLLELAR 7 0 P49321;P49321-3;E9PPR5;P49321-2;E9PI86;E9PPQ8 P49321 NASP Nuclear autoantigenic sperm protein 0 124.59 0.021338 2352500.0 27054.0 24014.0 25152.0 23876.0 24446.0 24156.0 24916.0 15874.0 24552.0 21423.0 False True 26668.20499890401 23958.39705841575 23084.099649527707 25631.920688001133 23008.134342685207 23122.90419038629 26206.02856507568 16611.563990886083 21786.695215978238 25125.937005646836 1.0613815115794711 0.9535324813172662 0.9187358721921398 1.0201379030059887 0.9157124901457139 0.9202802739332514 1.0429871156321893 0.6611321196559865 0.8670998104899279 1.0 14.61688977835618 -7.737015946828439 24.999991723723774 0.8230867006683564 0.9702577631018715 0.2998393393081721 0.09162595938163562 230.8116525163045 236260.67450429584 0.04073757119326658 0.02350597217962504 1.8322471429824372e-08 7.737015946828439 0.14717106243351508 SLLFGAMSEMIS(ph)PSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLLFGAMSEMISPSEK 16 0 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 SLLFGAMS(0.323)EMIS(0.369)PS(0.308)EK 76.158 0.0069979 5033100.0 32789.0 33300.0 38354.0 38746.0 38654.0 34052.0 41811.0 37532.0 40468.0 33745.0 True False 38339.530087730214 36605.80392796684 39268.50481835497 36575.18723622686 31080.026180060748 32266.25317487997 37850.359394573854 36546.82476844112 41059.767942065635 39862.70137472699 0.9617895618092138 0.9182971215085531 0.9850939214885036 0.9175290678974302 0.779676868556769 0.8094346861132904 0.9495181733612023 0.9168175639900776 1.0300297402347547 1.0 15.282751860119458 -8.13986902706685 2.6003254605703785 1.0164470563637482 0.8993333621340887 0.3349765838909431 0.06147673357779521 0.3759997897103545 4.55385734487597 0.05927194134975646 0.018452526705418644 7.246544657548245e-09 8.13986902706685 -0.11711369422965956 SLLFGAMSEMISPS(ph)EK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLLFGAMSEMISPSEK 16 0 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 SLLFGAMS(0.001)EMIS(0.358)PS(0.641)EK 97.76700000000001 0.01006 0.0 15029.0 17265.0 15830.0 17047.0 21859.0 25336.0 20713.0 21335.0 18624.0 15841.0 True False 17573.112863719467 18978.955099590028 16207.447235609317 16091.911857119692 17575.885866144454 24007.335558521067 18750.914690866226 20774.97885630107 18896.340766853573 18712.847902712994 0.9390934482597763 1.0142205610958048 0.8661133420135134 0.8599392214793069 0.9392416353470332 1.2829332917861465 1.0020342594751552 1.1101986701494595 1.0098057155754456 1.0 14.191741518163294 -6.558046547153746 24.99930722827341 1.0860736397951496 0.9198507082149789 0.45134872851114627 0.08681985245298748 157.4446086944953 111919.72549604219 0.02803711675482625 0.028037186870804472 2.766645103866922e-07 6.558046547153746 -0.16622293158017065 SLLGDSAPTLHLNKGT(ph)PS(ph)QSPVVGR ddPTM_PC-9_AZD4547_30min_R2 1 SLLGDSAPTLHLNKGTPSQSPVVGR 25 1 P52594-2;P52594-3;P52594;P52594-4;C9J2I0;B8ZZY2 P52594-2 AGFG1 Arf-GAP domain and FG repeat-containing protein 1 2 SLLGDSAPTLHLNKGT(0.996)PS(0.502)QS(0.502)PVVGR 77.51 0.00016237 8128200.0 15377.0 13341.0 32303.0 43820.0 35115.0 33727.0 26515.0 35781.0 24193.0 36688.0 True False 20266.566138530678 17653.217352525822 31874.64111359474 33717.976012251194 30239.888379020937 31618.04535833543 28874.783633638814 30251.868615582916 25471.792589011602 35403.564286958084 0.572444231158851 0.4986282513658911 0.9003229407988357 0.9523893057477316 0.8541481341798307 0.8930752028824069 0.8155897355305456 0.854486524870239 0.7194697229508856 1.0 15.111606991842558 -5.262043764953343 24.999994261790654 0.8692190632052695 0.5355362173264876 0.771863470809906 0.07350311025607305 22.378178035918346 925705.732492051 0.018872009506966617 0.043439266389823504 5.469608414893069e-06 5.262043764953343 -0.33368284587878194 SLLGDSAPTLHLNKGT(ph)PS(ph)QSPVVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLLGDSAPTLHLNKGTPSQSPVVGR 25 1 P52594-2;P52594-3;P52594;P52594-4;C9J2I0;B8ZZY2 P52594-2 AGFG1 Arf-GAP domain and FG repeat-containing protein 1 2 SLLGDS(0.002)APT(0.049)LHLNKGT(0.939)PS(0.505)QS(0.505)PVVGR 50.873000000000005 0.027760000000000003 4460500.0 6320.0 4659.7 9919.6 12465.0 12388.0 11839.0 8929.3 10861.0 7952.1 7471.6 True False 7389.85117431014 5122.2842211155275 10156.120884292488 11766.626462075252 9960.660328002075 11218.141998631632 8083.452061466314 10575.91025818072 8068.3844186048345 8826.14193484694 0.8372685629645148 0.5803537104804508 1.1506863314983176 1.3331562701953426 1.1285406921313925 1.2710130973920455 0.9158533956440951 1.1982483780852684 0.9141462349194311 1.0 13.107567232412576 -5.270424833047892 24.914254173125677 1.1279194795962642 0.7088111351973627 0.5564483025044871 0.14425666731989711 370.2082835008652 1026490.1504141756 0.036818977971285125 0.07846707424823397 5.365067210779876e-06 5.270424833047892 -0.41910834439890143 SLLGDSAPTLHLNKGT(ph)PS(ph)QSPVVGR ddPTM_PC-9_Lapatinib_30min_R1 1 SLLGDSAPTLHLNKGTPSQSPVVGR 25 1 P52594-2;P52594-3;P52594;P52594-4;C9J2I0;B8ZZY2 P52594-2 AGFG1 Arf-GAP domain and FG repeat-containing protein 1 2 SLLGDSAPT(0.007)LHLNKGT(0.976)PS(0.592)QS(0.425)PVVGR 59.996 0.004355899999999999 9663000.0 36417.0 27157.0 32979.0 30597.0 29797.0 25202.0 19057.0 20393.0 27861.0 19873.0 True False 35897.6869019401 27094.119635021107 30267.59392262143 32847.20544859987 28044.399043155976 24124.169208731397 20043.67821338287 21340.533228306664 24723.00079066346 23308.02157089202 1.5401430272730892 1.1624375562127212 1.2985912952998464 1.4092661339227848 1.203208043971391 1.0350157406263352 0.8599476430215 0.9155875012127828 1.0607078217886379 1.0 14.50853893051999 -6.6979556542264795 2.514271458215239 0.9521770158067948 1.3341488654051377 0.7521592114335289 0.10290248796702182 0.14031784685721854 1.8127605154069237 0.037693113704518666 0.03626084099432952 2.0046767142877e-07 6.6979556542264795 0.38197184959834285 SLLGLDSGELQSGPESSS(ph)SPGVHVR ddPTM_PC-9_AZD4547_30min_R2 1 SLLGLDSGELQSGPESSSSPGVHVR 25 0 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7 P49815 TSC2 Tuberin 1 SLLGLDSGELQSGPES(0.008)S(0.089)S(0.751)S(0.152)PGVHVR 151.06 3.3555999999999997e-07 3457000.0 4778.6 4539.2 14708.0 26955.0 18941.0 16175.0 9686.2 23281.0 15573.0 17776.0 True False 6298.095398945354 6006.407631106006 14512.962309963514 20740.941200598587 16311.369095458791 15163.574693007848 10548.253035344223 19683.456394158515 16396.15698709039 17153.667650593303 0.3671573640828653 0.35015296748495994 0.846055934251562 1.209125746346217 0.9508968826788842 0.8839844050775565 0.614926979477732 1.147478008499116 0.9558397260030446 1.0 14.066229453650857 -5.312832231406626 4.1819529321085875 0.9574270588958901 0.35101953409921965 0.7152037530057838 0.1507274260545315 0.1102197599769991 4.085453886165674 0.04181204490969989 0.09812396845698028 4.8659514180389375e-06 5.312832231406626 -0.6064075247966705 down SLLLEPPRGT(ph)PDR ddPTM_PC-9_AZD4547_30min_R2 2 SLLLEPPRGTPDR 13 1 Q53GT1-3;Q53GT1 Q53GT1-3 KLHL22 Kelch-like protein 22 1 SLLLEPPRGT(1)PDR;SLLLEPPRGT(1)PDR 86.911 0.005305699999999999 23965000.0 29810.0 32902.0 46093.0 54923.0 58652.0 48365.0 41940.0 47689.0 36985.0 43706.0 True False 39288.959913481114 43536.928066322216 45481.77670336879 42261.35090189117 50509.182207214464 45340.72890431681 45672.57875145433 40319.76083420064 38939.95159362601 42175.86624307106 0.93155075196436 1.032271105361701 1.0783839374215782 1.002026861957676 1.1975849391241005 1.0750396599563785 1.0829079001775745 0.9559912913661767 0.9232756802007197 1.0 15.364130079639025 -7.769231279387693 24.77447457540693 0.9547250588579451 1.0609462303352946 0.3108295339758087 0.06613061686868794 190.328991570352 605141.1353261907 0.03640997548483861 0.01800775255432505 1.7012522814248485e-08 7.769231279387693 0.10622117147734944 SLLLEPPRGT(ph)PDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLLLEPPRGTPDR 13 1 Q53GT1-3;Q53GT1 Q53GT1-3 KLHL22 Kelch-like protein 22 1 SLLLEPPRGT(1)PDR;SLLLEPPRGT(1)PDR;SLLLEPPRGT(1)PDR 95.06700000000001 0.0026016999999999998 21839200.0 49467.4 54693.2 55906.0 55850.0 64855.0 55864.0 53670.0 44962.0 44202.6 48597.6 True False 57841.253794314805 60122.77944123351 57239.01106468567 52720.90556814305 52147.12831551296 52934.39349704852 48585.98906284893 43781.79514117686 44848.9794018966 57407.960181610084 1.0075476225132194 1.047289944652886 0.9970570437202446 0.9183553186937919 0.9083605853708356 0.9220741048730972 0.8463284344043431 0.7626432815705897 0.7812327638887856 1.0 15.80896317426058 -6.161822351757208 0.8183725585616032 0.8346891553838945 1.0391766152305402 0.5118828980231191 0.06470917126434486 0.5169096089938109 0.7285519234208113 0.03385233954554835 0.06519284979284992 6.889340473220476e-07 6.161822351757208 0.20448745984664563 SLLLEPPRGT(ph)PDR ddPTM_PC-9_Lapatinib_30min_R1 1 SLLLEPPRGTPDR 13 1 Q53GT1-3;Q53GT1 Q53GT1-3 KLHL22 Kelch-like protein 22 1 SLLLEPPRGT(1)PDR 97.76700000000001 0.0021108 11579000.0 17454.0 22003.0 23831.0 19484.0 26360.0 22665.0 22271.0 20531.0 25565.0 16278.0 True False 17205.102759328416 21952.053405360282 21871.70717032026 20916.918356718645 24809.55662575399 21695.670784695543 23424.083407160095 21484.945212100425 22685.600488615324 19091.630610928398 0.9011856090217826 1.1498260076745108 1.1456175544167766 1.0956066971432716 1.2994990910599615 1.1363969493667316 1.2269294270627529 1.1253593603367777 1.1882484503775006 1.0 14.220652707741015 -4.760393794157455 5.493960947708737 1.1611814572537258 0.8882692354976164 0.4970844627466735 0.07523784661263974 0.11781938723710118 11.235721859794475 0.01750618656939036 0.1225655438543986 1.7362258014889518e-05 4.760393794157455 -0.2729122217561094 SLLS(ph)PLHR ddPTM_PC-9_AZD4547_30min_R2 2 SLLSPLHR 8 0 Q9BY84 Q9BY84 DUSP16 Dual specificity protein phosphatase 16 1 S(0.001)LLS(0.999)PLHR;SLLS(1)PLHR 82.26100000000001 0.015226 0.0 11286.4 12744.0 21128.0 32365.0 30200.0 22726.0 16652.2 24484.0 21100.0 21945.0 True False 14875.240428296314 16863.248777497105 20847.82891521005 24903.749284265406 26007.25128994538 21304.939627406246 18134.213540414105 20700.56038634841 22215.30292349624 21176.712229538138 0.7024338937537115 0.7963109945827928 0.9844695762607877 1.1759969637557168 1.2281061860806424 1.006055113583177 0.8563280902084398 0.9775153084185764 1.0490440009148085 1.0 14.37019100200877 -5.222855470219233 2.9200845457646074 1.0416572326030584 0.7214214653737379 0.5862218567433205 0.09794963744987692 0.2123808221014046 3.5514480561938235 0.030280525554927933 0.09760187230227005 5.9861077486378276e-06 5.222855470219233 -0.32023576722932057 SLLS(ph)PLHR ddPTM_PC-9_Lapatinib_30min_R1 2 SLLSPLHR 8 0 Q9BY84 Q9BY84 DUSP16 Dual specificity protein phosphatase 16 1 S(0.001)LLS(0.999)PLHR;SLLS(1)PLHR 87.568 0.011616 0.0 7385.1 6396.9 9203.7 6119.799999999999 14193.8 18541.3 19406.9 18487.8 23794.6 15572.3 True False 7279.787119738526 6382.088371074367 8447.007313309403 6569.870507054333 13358.948590084474 17748.331820881343 20411.69432330901 19346.810681032126 21114.601579753802 18263.951306214534 0.39858774247068257 0.3494363439801103 0.4624961582346754 0.3597179162878546 0.7314380314592126 0.9717684592622766 1.1175946530455148 1.0592894361500589 1.1560806982971588 1.0 14.156711297839657 -6.574857329227571 1.8686420937960586 1.0871657674301916 0.3861686161086902 0.9715576492069963 0.054007096499371965 0.047331841772772644 0.3362321845140128 0.019472662921579956 0.020390007631214516 2.66159928241714e-07 6.574857329227571 -0.7009971513215014 down SLLS(ph)SPTK ddPTM_PC-9_AZD4547_30min_R2 1 SLLSSPTK 8 0 Q92667-2;Q92667;I3NI36 Q92667-2 AKAP1 A-kinase anchor protein 1, mitochondrial 1 S(0.002)LLS(0.499)S(0.499)PTK 87.806 0.011448999999999999 4770000.0 97811.0 111070.0 120830.0 84680.0 92036.0 86317.0 144670.0 123180.0 119000.0 96610.0 True False 128912.86340481385 146971.20540776872 119227.7152510805 65158.33429295818 79258.39005700043 80919.58434475161 157545.34973707463 104145.36139480483 125290.09705668496 93227.71330579523 1.382774057559131 1.5764754942094314 1.2788870500341776 0.6989159337120392 0.8501591130635784 0.867977787670584 1.6898982518246672 1.1171073246556926 1.3439147289360434 1.0 16.508471260455323 -7.222838319885698 24.9979588595076 1.2974900105860383 1.1077276204422228 0.0785452206410906 0.29879710958427924 1629.4867809336167 1055252.8890599299 0.1261235814483245 0.09769306426310635 5.986344145313066e-08 7.222838319885698 -0.18976239014381546 SLLS(ph)SPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLLSSPTK 8 0 Q92667-2;Q92667;I3NI36 Q92667-2 AKAP1 A-kinase anchor protein 1, mitochondrial 1 SLLS(0.499)S(0.499)PT(0.001)K;SLLS(0.498)S(0.498)PT(0.004)K 103.26 0.0040284 26918000.0 310260.0 370550.0 287150.0 239743.0 346650.0 204174.0 257130.0 221137.0 201557.0 199711.0 True False 362780.8900856754 407335.75512036314 293996.74502243917 226310.97696729304 278726.42094784696 193466.75601221484 232772.78494001032 215332.38806401947 204504.38981661887 235917.02338859424 1.5377478270744178 1.7266060298218242 1.246187073741508 0.9592820972250127 1.1814595527883487 0.8200627204995851 0.9866722697522134 0.9127462909250577 0.8668488050553538 1.0 17.847919999297332 -5.497109164776043 2.702085517614169 0.9600992377900863 1.6351370622563823 0.8695669332390131 0.10323301314239317 0.08641262863972154 1.2483931273016151 0.028809637796886087 0.06619098425350103 3.1833972386448845e-06 5.497109164776043 0.675037824466296 SLLSS(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 1 SLLSSPTK 8 0 Q92667-2;Q92667;I3NI36 Q92667-2 AKAP1 A-kinase anchor protein 1, mitochondrial 1 S(0.002)LLS(0.056)S(0.925)PT(0.017)K 79.07 0.021233000000000002 7326900.0 95179.0 121420.0 118440.0 82923.0 92224.0 86676.0 149320.0 133930.0 131490.0 95101.0 True False 125443.94215381457 160666.64050248754 116869.4082126787 63806.383497578776 79420.28950211668 81256.1360179997 162609.1907288309 113234.19590522943 138440.29295784468 91771.5429364914 1.3669154744475143 1.7507239756628432 1.2734820018614676 0.695274171664899 0.8654130350306722 0.8854175642903959 1.771891215138022 1.2338704600792296 1.5085318229164941 1.0 16.48575924311215 -7.244131568219537 24.989366415881424 1.3980626442832813 1.140753290299612 0.10820038954038669 0.3343134790389412 2017.0679801969293 2912287.1685969867 0.1410997735688963 0.10903025738219793 5.699915688742819e-08 7.244131568219537 -0.2573093539836693 SLLSS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLLSSPTK 8 0 Q92667-2;Q92667;I3NI36 Q92667-2 AKAP1 A-kinase anchor protein 1, mitochondrial 1 SLLS(0.149)S(0.851)PTK 120.27 0.003423 13345000.0 250780.0 297790.0 245820.0 188560.0 287130.0 147020.0 204810.0 161170.0 164040.0 149370.0 True False 293232.1008692243 327352.62317445176 251681.28107754086 177995.5945197681 230868.93767995146 139310.01238608174 185408.91410400803 156939.4582737309 166438.7746668092 176449.59858773035 1.6618462338038698 1.8552188601987256 1.4263635796961334 1.00876168574149 1.3084129379028535 0.7895173097649022 1.0507754938973304 0.8894293868041925 0.9432652496744344 1.0 17.428896622513363 -5.590660683336333 2.1216938188775507 0.9886508393579269 1.771674049610405 0.8366219969963211 0.1361663329534934 0.11520484622793334 1.035336096340423 0.03945943448370536 0.0911675994139642 2.5664884649119678e-06 5.590660683336333 0.7830232102524782 SLLSS(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 1 SLLSSPTK 8 0 Q92667-2;Q92667;I3NI36 Q92667-2 AKAP1 A-kinase anchor protein 1, mitochondrial 1 SLLS(0.227)S(0.773)PT(0.001)K 101.66 0.0045165 9159700.0 153190.0 256450.0 111890.0 95296.0 118550.0 109940.0 122510.0 101630.0 155930.0 57481.0 True False 151005.48250839426 255856.2057812407 102690.83610789028 102304.3857381368 111577.12207826757 105238.12248265742 128852.96835396627 106352.10081855554 138367.52138430622 67416.51426138198 2.2398886113115806 3.795156254879261 1.523229689831567 1.517497409336388 1.6550413989911963 1.561013998360053 1.9112968056222506 1.5775378182000865 2.052427701139199 1.0 16.040814414943018 -5.279828922614141 24.936305845904027 1.6291614228393907 3.017522435903188 0.6286499601150557 0.435396054438933 393.0582408434215 532988.39384911 0.10397610440699669 0.21709131099765416 5.250142332530044e-06 5.279828922614141 1.3883610130637971 SLLVQTK ddPTM_PC-9_Lapatinib_30min_R1 1 SLLVQTK 7 0 P39023;G5E9G0 P39023 RPL3 60S ribosomal protein L3 0 119.41 0.029965 4719300.0 52785.0 48331.0 39637.0 44647.0 49791.0 43409.0 40163.0 39383.0 38668.0 46110.0 False True 52032.27622041653 48219.09253894777 36378.19886324467 47930.489318025924 46862.3912728724 41552.49826132135 42242.44362093172 41212.87795471003 34312.802647908386 54080.052062287024 0.9621343589035019 0.8916243735011783 0.6726731479723033 0.8862877806186594 0.8665374659569182 0.7683516689936432 0.7811095220891935 0.7620717137484049 0.6344816866741994 1.0 15.722808920037282 -6.766917418699413 24.776301499157324 0.7738265498490413 0.8493531509670115 0.07594063977887466 0.108708033038132 298.444284054665 1349805.2763070955 0.03727203701018484 0.033796344076082216 1.7103405062256952e-07 6.766917418699413 0.07552660111797016 SLMS(ph)SPEDLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLMSSPEDLTK 11 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 SLMS(0.492)S(0.492)PEDLT(0.017)K 84.507 0.010541 5072900.0 27056.0 40455.0 34314.0 33230.0 34512.0 28031.0 30038.0 18754.0 24225.0 27379.0 True False 31636.04641964164 44471.10504221916 35132.17589656966 31368.230833113572 27749.621346464934 26561.005014244718 27192.583183712635 18261.7273715055 24579.24479580262 32342.59596795526 0.9781542103480604 1.3750011002914149 1.086250959303894 0.9698736262294133 0.8579899205975611 0.8212391188561707 0.8407668701255394 0.5646339393906119 0.759965119069462 1.0 14.981147860457131 -6.04505893687854 1.34422622569075 0.7702815208353564 1.1878454412233526 0.5549449351792206 0.13646201521544346 0.29108554656389707 1.0661928938701062 0.04894900899831822 0.08545743383985 9.014487962326366e-07 6.04505893687854 0.41756392038799617 SLMS(ph)SPEDLTK ddPTM_PC-9_Lapatinib_30min_R1 2 SLMSSPEDLTK 11 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 SLMS(0.964)S(0.036)PEDLTK;S(0.012)LMS(0.565)S(0.423)PEDLTK 135.1 6.0038000000000004e-05 27833000.0 108196.0 127284.0 103034.0 103725.0 140678.0 127221.0 136826.0 159727.0 123764.0 127971.0 True False 106653.10519928353 126989.28171830537 94562.9422427417 111353.28251645682 132403.59662358934 121780.05439663572 143910.1807852402 167148.49953208168 109824.39502730237 150090.61683936065 0.7105914243355563 0.8460840816865971 0.6300390006655163 0.7419070216470379 0.8821577218601119 0.8113768665963628 0.958821969125923 1.1136505602543947 0.7317205921329878 1.0 17.195474261772105 -6.720689705441625 1.3262982933166452 0.9547062746844963 0.7347414199127134 0.4256683282508501 0.10699988027382251 0.4081691838916423 1.5056735751017403 0.04924218499708663 0.04610590648184132 1.902437046966863e-07 6.720689705441625 -0.21996485477178296 SLMS(ph)SPEDLTKDFEELKAEEVDVTK ddPTM_PC-9_AZD4547_30min_R2 1 SLMSSPEDLTKDFEELKAEEVDVTK 25 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.002)LMS(0.498)S(0.498)PEDLT(0.003)KDFEELKAEEVDVTK 74.65 0.00016286 4376500.0 13061.0 9070.3 9271.0 11736.0 11887.0 10132.0 9585.2 9630.3 11858.0 10722.0 True False 17214.12631432328 12002.097095616136 9148.06048243621 9030.446519392508 10236.695234555656 9498.444438303273 10438.264231007146 8142.1584172786725 12484.789671413197 10346.626043522807 1.663742967215836 1.1600010520463033 0.8841588015218814 0.8727914279888125 0.9893752022635467 0.9180233632053889 1.0088568183578748 0.7869385037237163 1.2066532238525158 1.0 13.336872772024412 -4.803660860748472 2.6188580228449556 0.9501067182848486 1.7902473357456212 0.8004142098744698 0.10635147050757018 0.17499046895866008 1.6403628138917037 0.02572298432936992 0.3220816082342533 1.5715895748411942e-05 4.803660860748472 0.8401406174607726 SLMS(ph)SPEDLTKDFEELKAEEVDVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLMSSPEDLTKDFEELKAEEVDVTK 25 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.005)LMS(0.336)S(0.336)PEDLT(0.322)KDFEELKAEEVDVTK 59.538999999999994 0.0096838 11228000.0 20140.0 13725.0 9904.8 21075.0 19588.0 19573.0 23440.0 23553.0 21830.0 20381.0 True False 23549.304216868073 15087.52729463499 10140.967996163181 19894.23607607187 15749.872013634546 18546.557423702747 21219.593509095947 22934.75870646632 22149.22245169747 24075.91396409278 0.9781271129307864 0.6266647786304927 0.42120801774286076 0.8263128081344063 0.654175456729251 0.7703365883165804 0.8813619096971024 0.9526017886868845 0.9199743147749735 1.0 14.55530294590214 -7.262819484579288 1.611054649380345 0.9580697587278444 0.6856329914778214 0.4113988875541815 0.13558051596850293 0.39424126431271533 1.9965146498764148 0.07795892807283353 0.04713004765763681 5.4598475365240646e-08 7.262819484579288 -0.27243676725002297 SLMS(ph)SPEDLTKDFEELKAEEVDVTK ddPTM_PC-9_Lapatinib_30min_R1 2 SLMSSPEDLTKDFEELKAEEVDVTK 25 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.008)LMS(0.53)S(0.453)PEDLT(0.009)KDFEELKAEEVDVTK;S(0.006)LMS(0.495)S(0.495)PEDLT(0.005)KDFEELKAEEVDVTK 109.75 2.8919e-07 18471800.0 65014.0 43761.0 47776.0 51077.0 51203.0 46251.0 47516.0 50453.0 48787.0 54410.0 True False 64086.88843789256 43659.67409316782 43848.041700693226 54833.37296787713 48191.340208971196 44272.952546346954 49976.14598242644 52797.23056773186 43292.094310114466 63814.69600323223 1.0042653565982127 0.6841633170352555 0.6871151074428422 0.8592593305639159 0.7551762090432945 0.6937736182916944 0.7831447787496337 0.8273522225203057 0.6784032052416533 1.0 15.961601082685206 -10.656831321093872 4.658622608693253 1.0000157526354394 0.7708218829576787 0.32421058955596616 0.09741844595158304 132796691.6016709 1.2722291560778791 30146.406997025893 0.022517741150362567 2.2037822404411043e-11 10.656831321093872 -0.22919386967776068 SLMSS(ph)PEDLTK ddPTM_PC-9_AZD4547_30min_R2 3 SLMSSPEDLTK 11 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 SLMS(0.344)S(0.656)PEDLTK;SLMS(0.003)S(0.997)PEDLTK;SLMS(0.15)S(0.85)PEDLTK 150.09 0.00010683 35081000.0 191316.0 224106.0 198857.0 169530.0 189007.0 221650.0 226035.0 238815.0 219864.0 192580.0 True False 252150.50837999175 296543.88186831214 196220.02624914417 130447.47771239045 162766.64054830125 207790.19046090802 246151.67711218388 201911.6291727577 231485.56217874805 185837.83281678986 1.3568308700014649 1.5957131945283873 1.0558669527888311 0.7019425255620229 0.8758530923505033 1.118126418670412 1.3245509452042257 1.086493670919066 1.2456320581770908 1.0 17.503684709531832 -5.2727149024771265 23.66701698598484 1.0475843756141245 1.4762720129926818 0.4889639593813261 0.17385300811852397 283.543188832119 595151.6015911001 0.05067764750378115 0.10722702428280724 5.336851241529707e-06 5.2727149024771265 0.4286876373785573 SLMSS(ph)PEDLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLMSSPEDLTK 11 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 SLMS(0.042)S(0.958)PEDLTK;SLMS(0.189)S(0.811)PEDLTK 117.86 0.00098683 25545000.0 141974.0 231536.0 184184.0 189235.0 205905.0 138821.0 190464.0 136832.0 139740.0 157335.0 True False 166007.39408568162 254521.36391188356 188575.6450817098 178632.7764581473 165559.39335140985 131540.98237959627 172421.87108005353 133240.3049854881 141783.4331378928 185858.59003682487 0.8931919372292125 1.3694355685225754 1.0146189371411167 0.9611219821626437 0.8907814985500909 0.7077476610230045 0.9277046115861038 0.7168907552730744 0.7628564981032123 1.0 17.50384584284707 -5.948122844652174 1.685728915436306 0.8147894528139786 1.1338198012857568 0.4116299084379217 0.13965200797281174 0.3103127312248072 1.7875897098487452 0.043948798607784806 0.07719923672853708 1.1268786618937624e-06 5.948122844652174 0.31903034847177814 SLMSS(ph)PEDLTK ddPTM_PC-9_Lapatinib_30min_R1 3 SLMSSPEDLTK 11 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 SLMS(0.005)S(0.995)PEDLTK;SLMS(0.005)S(0.995)PEDLTK;S(0.001)LMS(0.057)S(0.942)PEDLTK 152.96 0.00035472 31679700.0 139219.0 182984.0 147027.0 146102.0 182375.0 174377.0 202880.0 211115.0 171782.0 181820.0 True False 137233.711530362 182560.31179050318 134939.00760063287 156846.82846198446 171648.0610630454 166919.30220264097 213384.13370053598 220924.17361319906 152434.10221534604 213247.3447400789 0.6435424164255468 0.8560965296567736 0.6327816543981177 0.7355159739651651 0.8049247284755753 0.7827497332081398 1.000641456805119 1.0359996457750844 0.7148229789268589 1.0 17.702168252303146 -7.10244593447346 3.7936915516416247 0.9401136766500454 0.7391408394886281 0.46547225776962087 0.10313314713139718 0.2208875717046624 5.724191589214808 0.0401509631098608 0.030895462130404557 7.898671742195728e-08 7.10244593447346 -0.20097283716141734 SLMSS(ph)PEDLTKDFEELKAEEVDVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLMSSPEDLTKDFEELKAEEVDVTK 25 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.019)LMS(0.446)S(0.534)PEDLT(0.001)KDFEELKAEEVDVTK 92.792 0.00044606 0.0 16573.0 16991.0 9034.8 16782.0 18129.0 15902.0 20060.0 21975.0 14382.0 17633.0 True False 19378.48156832942 18677.754190392934 9250.223896669808 15841.758947978095 14576.752590115408 15068.071126128909 18159.771578176827 21398.1795344371 14592.309541929133 20829.723317248805 0.9303283232899386 0.8966875798549924 0.44408769889947725 0.7605362158056009 0.6998053871433136 0.7233927641108535 0.8718201054134489 1.027290627366018 0.7005522502473878 1.0 14.346356055630643 -7.3278653194882555 4.7250471903895015 0.9060164330466626 0.7346961385624525 0.21575698191657533 0.1473583227855691 0.35362829081464614 15.63722625601305 0.06464889890152234 0.04317908257565525 4.70039851633312e-08 7.3278653194882555 -0.17132029448421005 SLMSVSGAET(ph)VNGEVPATPVKR ddPTM_PC-9_AZD4547_30min_R2 1 SLMSVSGAETVNGEVPATPVKR 22 1 Q8IUW5 Q8IUW5 RELL1 RELT-like protein 1 1 S(0.327)LMS(0.097)VS(0.073)GAET(0.502)VNGEVPATPVKR 54.958 0.006307699999999999 5165000.0 14386.0 18932.0 18225.0 19425.0 21713.0 11928.0 18332.0 23742.0 20537.0 10686.0 True False 18960.448752611184 25051.39876456178 17983.32459199654 14946.866363258307 18698.524743661725 11182.140274386249 19963.512486210308 20073.219436884658 21622.543892883525 10311.886392565253 1.838698374943448 2.429371097670698 1.7439413030153537 1.4494793478363783 1.8132981718207386 1.0843932767188396 1.9359709490790902 1.9466098318690952 2.0968562947389646 1.0 13.33202065408454 -5.430022994712911 7.080191232604864 1.6522171958075076 2.129816670439995 0.2304839458847565 0.3680404625577032 0.381551881707797 25.096322573425585 0.09531743321855807 0.1995412488421436 3.7151555783696545e-06 5.430022994712911 0.4775994746324874 SLNDDGS(ph)SDPR ddPTM_PC-9_Lapatinib_30min_R1 1 SLNDDGSSDPR 11 0 P54259 P54259 ATN1 Atrophin-1 1 S(0.068)LNDDGS(0.466)S(0.466)DPR 115.92 0.0013119000000000002 4172500.0 24842.0 39994.0 28823.0 21086.0 33477.0 27048.0 33686.0 31091.0 29949.0 32459.0 True False 24487.74852453514 39901.39635022405 26453.284199997488 22636.734780833984 31507.948678314322 25891.220091967574 35430.09625313613 32535.601363275753 26575.828243048716 38069.49490110119 0.6432380725867423 1.0481199305081894 0.6948682736327112 0.5946161050899363 0.8276429398437574 0.680104113785304 0.9306689344100356 0.8546370643424175 0.6980872300010471 1.0 15.216347808170124 -7.262764513109711 24.99104023774219 0.8587347258769624 0.7559552538955834 0.1565497669894379 0.13772241893748358 285.253837860889 5379602.666524427 0.055528834154683994 0.03979837100037538 5.460538668581066e-08 7.262764513109711 -0.10277947198137904 SLNIFGS(ph)S(ph)WSVRPMFT(ph)YNWTEETLR ddPTM_PC-9_AZD4547_30min_R2 1 SLNIFGSSWSVRPMFTYNWTEETLR 25 1 F5H1T6;B7Z641;B7Z2A9;Q93050-1;Q93050;Q93050-3 F5H1T6 ATP6V0A1 V-type proton ATPase subunit a;V-type proton ATPase 116 kDa subunit a isoform 1 3 S(0.227)LNIFGS(0.785)S(0.675)WS(0.309)VRPMFT(0.487)Y(0.428)NWT(0.061)EET(0.029)LR 43.216 0.022775999999999998 9469100.0 12636.0 11900.0 12764.0 19553.0 12734.0 15819.0 10835.0 15820.0 11843.0 11954.0 True False 16653.98515487244 15746.442282816672 12594.741020150554 15045.357940838601 10966.103904839885 14829.835429285378 11799.294009823734 13375.382507434711 12468.996802036301 11535.494098514415 1.4437166724412094 1.3650427236441098 1.0918250152607294 1.3042664503444374 0.9506401556091248 1.2855830277088194 1.0228685402685345 1.1594980148407552 1.0809243796190842 1.0 13.49379217968737 -1.5228787477939345 0.4660244382705936 1.0846177913404773 10.854207796038635 0.5409401070205273 0.10865377393225595 68.54295694686716 0.7953988320693832 0.060083713378167834 643.4977033240798 0.029999999826366874 1.5228787477939345 9.769590004698157 SLNS(ph)TPPPPPAPAPAPPPALAR ddPTM_PC-9_AZD4547_30min_R2 1 SLNSTPPPPPAPAPAPPPALAR 22 0 B4DKV7;Q8TE68-2;Q8TE68;K7ELW3;Q8TE68-4 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 SLNS(0.889)T(0.111)PPPPPAPAPAPPPALAR 164.97 1.3015000000000001e-08 7725200.0 13022.0 17690.0 20170.0 20475.0 17998.0 20003.0 17251.0 20052.0 20432.0 19468.0 True False 17162.72512557367 23407.946553195547 19902.532621156122 15754.805085596605 15499.28836809394 18752.2092478662 18786.305580384796 16953.42414912016 21511.993807245275 18786.43124559803 0.9135702732042404 1.246002832958517 1.0594099731325828 0.8386268195183806 0.8250256882464401 0.9981783662216396 0.9999933108523067 0.9024292015596431 1.1450814434107004 1.0 14.197403411540268 -3.1342816097280624 11.002711182332588 0.990406108951619 1.0738476173508282 0.0 0.12581389470027998 0.0 0.0 0.030106685367933376 0.0 0.0007340377414479709 3.1342816097280624 0.08344150839920927 SLNS(ph)TPPPPPAPAPAPPPALARPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLNSTPPPPPAPAPAPPPALARPR 24 1 B4DKV7;Q8TE68-2;Q8TE68;K7ELW3;Q8TE68-4 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 S(0.138)LNS(0.431)T(0.431)PPPPPAPAPAPPPALARPR 99.40899999999999 1.8993e-06 4999000.0 32204.0 29787.0 41955.0 55979.0 53505.0 44933.0 48243.0 37335.0 48515.0 38180.0 True False 37655.501142006906 32744.056504575045 42955.36631522353 52842.6781163667 43021.07933885625 42576.634379974246 43673.07379092642 36354.995809702385 49224.44009363735 45101.73176728628 0.8349014476051592 0.7260044176025487 0.9524105756484594 1.1716330181958816 0.9538675712239683 0.9440132942047347 0.9683236558691055 0.8060665164097274 1.0914090915094619 1.0 15.460895209130097 -5.34260472544917 5.896104460861568 0.9837535125947576 0.7814845791773833 0.43660354589658257 0.09371494691596512 0.1971794049253745 11.169662228730049 0.025061678350986754 0.053450482630376626 4.5435496118023844e-06 5.34260472544917 -0.20226893341737429 SLNS(ph)TPPPPPAPAPAPPPALARPR ddPTM_PC-9_Lapatinib_30min_R1 1 SLNSTPPPPPAPAPAPPPALARPR 24 1 B4DKV7;Q8TE68-2;Q8TE68;K7ELW3;Q8TE68-4 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 S(0.146)LNS(0.427)T(0.427)PPPPPAPAPAPPPALARPR 84.113 0.00019432 0.0 35039.0 22012.0 31939.0 15480.0 23630.0 23774.0 20924.0 20197.0 27371.0 18332.0 True False 34539.33743463435 21961.03256641325 29313.09870810534 16618.45083976618 22240.129858367472 22757.241439900816 22007.342338081697 21135.426352773495 24288.18975059222 21500.66177414543 1.6064313646460846 1.0214119359256848 1.3633579754905207 0.7729274109948507 1.0343928057652279 1.0584437669386728 1.0235658124972484 0.9830128288511041 1.1296484734157717 1.0 14.392093445112305 -2.367266038906205 1.1818652057865824 1.025335990777209 199.9999999890972 0.5811447669263279 0.1411136762903865 368.11668131418173 1.9539932658518746 0.039769627466886906 196935.40763124003 0.004292733831103707 2.367266038906205 198.97466399831998 SLNST(ph)PPPPPAPAPAPPPALAR ddPTM_PC-9_AZD4547_30min_R2 2 SLNSTPPPPPAPAPAPPPALAR 22 0 B4DKV7;Q8TE68-2;Q8TE68;K7ELW3;Q8TE68-4 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 S(0.009)LNS(0.057)T(0.934)PPPPPAPAPAPPPALAR;SLNS(0.149)T(0.85)PPPPPAPAPAPPPALAR 165.17 3.1065e-08 11326900.0 33137.0 38367.0 49409.0 59579.0 57419.0 47608.0 46798.0 60053.0 44169.0 53046.0 True False 43673.876707582145 50768.382442422444 48753.80437673291 45843.9820363741 49447.36297408521 44631.0642339856 50962.931340261326 50773.18873065596 46503.68316719935 51188.8756859458 0.8531907787061058 0.9917854565491305 0.9524296778043622 0.8955848594455618 0.9659786879761704 0.8718899103744002 0.9955860654750324 0.9918793497665359 0.9084724472658656 1.0 15.643542698828078 -7.292712931032503 24.99755841814569 0.9733077439307829 0.9271980158515556 0.22735121619989285 0.04648105891819303 1179.4089884535947 942719.4681632367 0.018778474303034493 0.012661814791375167 5.096676504257818e-08 7.292712931032503 -0.04610972807922731 SLNST(ph)PPPPPAPAPAPPPALAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLNSTPPPPPAPAPAPPPALAR 22 0 B4DKV7;Q8TE68-2;Q8TE68;K7ELW3;Q8TE68-4 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 S(0.007)LNS(0.024)T(0.969)PPPPPAPAPAPPPALAR 93.115 0.00046465 6412200.0 19347.0 21730.0 22070.0 22784.0 20595.0 17478.0 22982.0 13073.0 15399.0 15833.0 True False 22622.064979331997 23887.210791433034 22596.232500941085 21507.48634672465 16559.557592444533 16561.42291173948 20804.978584728804 12729.847601988457 15624.18124295416 18703.397566040952 1.209516340518047 1.277158906935932 1.2081351755024554 1.149924032293201 0.8853769767751231 0.8854767083500072 1.1123635965747534 0.6806168535443826 0.8353659375408024 1.0 14.191012746263784 -6.150592941636566 2.8190616305750615 0.891448834815451 1.2338911737902354 0.6776419809017744 0.10599912309971674 0.16384280755044445 2.5208588406899586 0.034320459392704734 0.046376834234877796 7.069798865342115e-07 6.150592941636566 0.3424423389747844 SLNST(ph)PPPPPAPAPAPPPALAR ddPTM_PC-9_Lapatinib_30min_R1 2 SLNSTPPPPPAPAPAPPPALAR 22 0 B4DKV7;Q8TE68-2;Q8TE68;K7ELW3;Q8TE68-4 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 SLNS(0.008)T(0.992)PPPPPAPAPAPPPALAR;S(0.001)LNS(0.042)T(0.956)PPPPPAPAPAPPPALAR 187.04 1.6365999999999997e-52 4699400.0 19293.7 30390.0 32575.0 27445.0 32761.0 26167.0 33440.0 27514.0 29087.0 19058.2 True False 19018.568299968756 30319.63382215604 29896.809243136348 29463.39685383612 30834.062390604187 25047.898408256257 35171.35957682337 28792.400884795272 25810.915760311123 22352.384476544757 0.850851877567053 1.3564384530863647 1.3375221455459596 1.3181321610118701 1.379452935903084 1.1205917844935072 1.5734947478972579 1.2881131726688166 1.1547276214488678 1.0 14.44814112098006 -4.757055540073585 24.98649200502472 1.3000852015871194 0.8508512071428153 0.41556013779910284 0.1514912992120083 118.44257668311278 674998.7608735943 0.03537716522037548 0.2718284555276845 1.7496229224849242e-05 4.757055540073585 -0.4492339944443041 SLNST(ph)PPPPPAPAPAPPPALARPR ddPTM_PC-9_AZD4547_30min_R2 1 SLNSTPPPPPAPAPAPPPALARPR 24 1 B4DKV7;Q8TE68-2;Q8TE68;K7ELW3;Q8TE68-4 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 S(0.08)LNS(0.233)T(0.687)PPPPPAPAPAPPPALARPR 109.37 5.8035e-07 17291000.0 36104.0 31977.0 48067.0 71646.0 59610.0 54058.0 40243.0 52409.0 43601.0 50879.0 True False 47584.32099014835 42312.93990568309 47429.600173580155 55129.12161966559 51334.18044349817 50677.74471435039 43824.54903897893 44310.39328901051 45905.6598467943 49097.74169636235 0.9691753499463678 0.8618103082492297 0.9660240682127792 1.1228443450740242 1.0455507457138609 1.0321807676564705 0.8925980610270287 0.9024935110669962 0.9349851594130539 1.0 15.583369047299472 -9.990872443628867 10.129050548751518 1.0000005903081788 0.9707790810611713 0.014223648721591431 0.07512694909957826 0.0 0.0 0.08185208237493398 0.01985204595933003 1.0212393872696285e-10 9.990872443628867 -0.029221509247007504 SLNST(ph)PPPPPAPAPAPPPALARPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLNSTPPPPPAPAPAPPPALARPR 24 1 B4DKV7;Q8TE68-2;Q8TE68;K7ELW3;Q8TE68-4 B4DKV7 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 S(0.034)LNS(0.074)T(0.892)PPPPPAPAPAPPPALARPR 87.49600000000001 1.2958e-05 7060300.0 19687.0 14820.0 24767.0 22880.0 22470.0 35482.0 26072.0 18904.0 24927.0 23464.0 True False 23019.620264025893 16291.231658032086 25357.539209370556 21598.10777796085 18067.164802244653 33621.261457508845 23602.271415066112 18407.79003044366 25291.51021774911 27717.837459078197 0.8304984217477783 0.5877526225515963 0.9148455122737364 0.779213306588137 0.6518244732807343 1.2129828492986254 0.8515192229520725 0.6641134993889902 0.9124633281758995 1.0 14.758527082595753 SLPAPVAQRPDS(ph)PGGGLQAPGQK ddPTM_PC-9_AZD4547_30min_R2 2 SLPAPVAQRPDSPGGGLQAPGQK 23 1 Q5JVS0-2;Q5JVS0 Q5JVS0-2 HABP4 Intracellular hyaluronan-binding protein 4 1 SLPAPVAQRPDS(1)PGGGLQAPGQK;SLPAPVAQRPDS(1)PGGGLQAPGQK 85.79799999999999 1.5342e-05 45218000.0 123648.0 96390.0 147328.0 160141.0 160811.0 151537.0 149332.0 159267.0 120837.0 161736.0 True False 162965.49196182878 127546.18249081504 145374.33445759505 123222.96660378629 138485.1684499138 142061.3674345798 162622.2587055836 134655.94474156824 127224.19712637507 156073.67186860737 1.0441574803149591 0.8172177982599874 0.9314468783689558 0.7895179573113595 0.8873064033919783 0.9102199348149891 1.0419583057063542 0.8627716842269852 0.8151547637930913 1.0 17.251867663462185 -6.876426175941293 5.2067351139382545 0.9258971739881049 0.886184820374102 0.031051585020376082 0.08740069671606863 0.8274895901184165 34.4300894099438 0.03120924176345366 0.027533446812821976 1.329149474962678e-07 6.876426175941293 -0.03971235361400294 SLPAPVAQRPDS(ph)PGGGLQAPGQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLPAPVAQRPDSPGGGLQAPGQK 23 1 Q5JVS0-2;Q5JVS0 Q5JVS0-2 HABP4 Intracellular hyaluronan-binding protein 4 1 SLPAPVAQRPDS(1)PGGGLQAPGQK;SLPAPVAQRPDS(1)PGGGLQAPGQK;SLPAPVAQRPDS(1)PGGGLQAPGQK;SLPAPVAQRPDS(1)PGGGLQAPGQK 136.85 2.7901e-08 50963000.0 189530.0 224942.0 229616.0 240190.0 255945.0 210650.0 221035.0 216555.0 194574.0 173908.0 True False 221613.68561186717 247272.75517011152 235090.91626352977 226732.93300648668 205794.41456655532 199603.1431718688 200096.96464518 210870.66070898925 197419.2766521567 205436.1437450298 1.0787473010928184 1.2036477645190118 1.1443503172221972 1.1036662238359023 1.001743952232525 0.971606746179969 0.974010517319307 1.02645355809786 0.960976355247288 1.0 17.64833050134311 -6.173086265951933 2.5667161294404175 0.986730912600409 1.1474345945063764 0.8246680388771107 0.032790115093797624 0.10770538828345427 1.3882580006367684 0.010196651930810343 0.01370728274177982 6.71295497105553e-07 6.173086265951933 0.1607036819059674 SLPAPVAQRPDS(ph)PGGGLQAPGQK ddPTM_PC-9_Lapatinib_30min_R1 4 SLPAPVAQRPDSPGGGLQAPGQK 23 1 Q5JVS0-2;Q5JVS0 Q5JVS0-2 HABP4 Intracellular hyaluronan-binding protein 4 1 SLPAPVAQRPDS(1)PGGGLQAPGQK;SLPAPVAQRPDS(1)PGGGLQAPGQK;SLPAPVAQRPDS(1)PGGGLQAPGQK;SLPAPVAQRPDS(1)PGGGLQAPGQK 119.5 8.741e-09 53217400.0 196218.0 240072.0 221785.0 219031.0 224739.0 215426.0 181988.0 188023.0 202741.0 174123.0 True False 193419.89533802582 239516.1280339802 203550.69341485776 235139.2704059962 211520.29387387433 206212.73216253344 191410.4481658773 196759.23499170798 179906.17362262312 204219.92854568647 0.9471156743390763 1.1728342563806036 0.9967229685388955 1.1514021774490666 1.0357475657746824 1.0097581251302865 0.9372760510150528 0.9634673579257989 0.8809432796485184 1.0 17.639764131108855 -6.9666753353145445 2.0282035282193522 0.9412554856542429 1.0704343685142852 0.389546200385976 0.06789390174467207 0.3048105655132845 2.5336719198363262 0.027502494691741364 0.021892257803582074 1.0797536099073036e-07 6.9666753353145445 0.1291788828600423 SLPAT(ph)PQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLPATPQGK 9 0 Q13111;Q13111-3;Q13111-2;K7EPA1 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 SLPAT(1)PQGK;S(0.001)LPAT(0.999)PQGK 87.568 0.026382999999999997 22218700.0 104385.0 110736.0 124188.0 129562.0 178790.0 185362.0 188471.0 187715.0 171584.0 137339.0 True False 122055.31880227289 121729.13825127107 127149.11290561248 122303.06118567163 143757.382954754 175641.29040884817 170617.66246812418 182787.68015048286 174093.0913949637 162237.4735250743 0.7523250710842021 0.750314558075619 0.783722219922028 0.7538521065958864 0.8860923424854483 1.0826185010931044 1.051653842734149 1.126667447285121 1.0730757057065308 1.0 17.307747565413713 -6.5805528547202625 2.6008039355424977 1.0761278800096559 0.7610157886022026 0.9509199741738003 0.03287402806469921 0.05276515018959128 0.7243166141206683 0.01137952233935644 0.011741050514428548 2.626921804086605e-07 6.5805528547202625 -0.3151120914074532 SLPAT(ph)PQGK ddPTM_PC-9_Lapatinib_30min_R1 1 SLPATPQGK 9 0 Q13111;Q13111-3;Q13111-2;K7EPA1 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 S(0.07)LPAT(0.93)PQGK 92.24700000000001 0.017547 24426000.0 172610.0 143590.0 167220.0 155610.0 190950.0 184040.0 179900.0 160450.0 214220.0 166250.0 True False 170148.54974720237 143257.52617714304 153471.81708786648 167054.07849974238 179718.69642214442 176169.0382181941 189214.34174253972 167905.09275152299 190092.28776339407 194986.0909857992 0.8726189077742691 0.7347063857369008 0.7870911012778025 0.8567486924588323 0.9217000839061557 0.9034954099932412 0.9703991745560977 0.8611131794203284 0.9749017830058373 1.0 17.57301168978863 -6.078686543230187 2.1565504634057895 0.9336483676340424 0.7913858085000459 0.6296862679510231 0.04863639471079807 0.19899282906713853 1.8319509424017488 0.014983958474219983 0.02205085351019379 8.342831202903244e-07 6.078686543230187 -0.14226255913399644 SLPGS(ph)PEFLHQEACPFVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLPGSPEFLHQEACPFVGR 19 0 Q96S53-3;Q96S53-2;Q96S53 Q96S53-3 TESK2 Dual specificity testis-specific protein kinase 2 1 S(0.286)LPGS(0.714)PEFLHQEACPFVGR 66.068 0.033941000000000006 0.0 2326.3 3502.3 2423.1 2380.4 2953.5 2050.3 2683.6 2800.4 2534.0 1116.4 True False 2720.0966434806433 3849.985198105654 2480.875893657923 2247.033905360926 2374.782876877152 1942.7786586531315 2429.38998041851 2726.8924672690628 2571.054956142986 1318.794482582463 2.0625629538229115 2.919321584183924 1.8811694516645783 1.7038544936590763 1.8007224842394343 1.4731473965896362 1.8421293177245321 2.0677160113145625 1.9495493726273005 1.0 10.365004041017503 -5.421355474484584 6.34179962680823 1.7411887314300178 2.485478982627686 0.4581479457667804 0.33982860002160176 0.19873274789602832 10.465736049056186 0.08479067637824916 0.17830554048468952 3.7900463879891633e-06 5.421355474484584 0.7442902511976681 SLPRQPVPS(ph)VQDT(ph)VRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLPRQPVPSVQDTVRK 16 2 M0QZ13;Q8TCG5-3;Q8TCG5-2;Q8TCG5 M0QZ13 CPT1C Carnitine O-palmitoyltransferase 1, brain isoform 2 SLPRQPVPS(1)VQDT(1)VRK;SLPRQPVPS(1)VQDT(1)VRK 113.67 0.0025859999999999998 11410100.0 30621.0 32312.0 37051.0 34179.0 39713.0 26424.0 29884.0 20631.5 21528.0 22970.6 True False 35804.53050768208 35519.72181743135 37934.43635669998 32264.061439813086 31931.52273215583 25038.278923206537 27053.171178576064 20089.944985881204 21842.806273025333 27134.987944830442 1.3194968275083865 1.3090008327863771 1.3979897995100077 1.189020666064449 1.1767656870560428 0.9227304236918463 0.9969848239320863 0.7403705145079525 0.8049683426222661 1.0 14.727866647288643 -6.628124641587703 1.123938369162592 0.8466094455814069 1.339038191320775 0.8474092431086974 0.08385824236171673 0.1657002338644783 0.44543983526285236 0.04056261387036555 0.04177498434361029 2.3543734867678754e-07 6.628124641587703 0.492428745739368 SLPS(ph)FSEIK ddPTM_PC-9_AZD4547_30min_R2 1 SLPSFSEIK 9 0 P35367 P35367 HRH1 Histamine H1 receptor 1 S(0.005)LPS(0.951)FS(0.044)EIK 93.561 0.012184 0.0 20733.0 29601.0 28272.0 30418.0 29104.0 19861.0 25522.0 33831.0 18630.0 23851.0 True False 27325.662726809936 39168.9443708955 27897.094807403348 23405.600053415263 25063.41197160827 18619.08853031398 27793.408557334682 28603.196309040693 19614.743766101194 23015.98374967938 1.1872472201928188 1.7018149124927644 1.2120748394164105 1.0169280752008398 1.08895679820583 0.8089634026863332 1.2075698722945898 1.2427535846448077 0.8522226979055124 1.0 14.490348487132003 -5.50464681096714 5.65941446775663 1.0456103293706254 1.450672876689809 0.47783716769288465 0.17210772344743044 0.13585909061864027 14.521737961131834 0.04462214132452009 0.08808592054855657 3.1286226783293246e-06 5.50464681096714 0.40506254731918356 SLPS(ph)PGVLCGSAR ddPTM_PC-9_AZD4547_30min_R2 2 SLPSPGVLCGSAR 13 0 P18848 P18848 ATF4 Cyclic AMP-dependent transcription factor ATF-4 1 S(0.001)LPS(0.991)PGVLCGS(0.007)AR;S(0.003)LPS(0.993)PGVLCGS(0.005)AR 99.669 0.0024486 8218000.0 29927.0 34941.0 36497.0 43758.0 38127.0 30662.0 29199.0 30515.0 20804.8 30669.0 True False 39443.16347972996 46234.99494150397 36013.02593328383 33670.26915436075 32833.72416992539 28744.700292859736 31797.65443404183 25799.607914941258 21904.499254158996 29595.28764491707 1.3327514823632487 1.5622417830915976 1.2168500054929858 1.137690214683335 1.1094240597984022 0.9712593652657598 1.0744161305525615 0.8717471586856596 0.7401346970155585 1.0 14.853079858358727 -5.896164766263202 0.6083922438274544 0.8831278911335465 1.5337757956290532 0.773364972895702 0.10557503365957424 0.5593832951138058 0.3661044697221442 0.06745641817080442 0.2172531813648194 1.2700921556348482e-06 5.896164766263202 0.6506479044955067 SLPS(ph)QSPPR ddPTM_PC-9_AZD4547_30min_R2 1 SLPSQSPPR 9 0 H7BYJ1 H7BYJ1 RNF34 1 S(0.007)LPS(0.921)QS(0.072)PPR 69.721 0.033682 0.0 1081.5 0.0 9115.3 12403.0 5501.3 3504.8 1948.4 9776.9 2017.0 3731.8 True False 1425.3945034025437 0.0 8994.425166168781 9543.679974439787 4737.539454350215 3285.6443019507797 2121.8038254490593 8266.104755811539 2123.6145022128894 3601.150817871518 0.3958163863420282 0.0 2.497653006236765 2.6501750293481563 1.3155626337111774 0.9123873084251383 0.5892016004770287 2.295406433629256 0.5897044055122536 1.0 11.814242306194998 -6.530100175532252 23.59860374144461 1.1262586122206315 1.443395115598938 0.024607067322158227 0.8805394690135495 476.1914571218743 1556099.8327242227 0.3166179813514577 0.31742572119489965 2.9505285713194515e-07 6.530100175532252 0.31713650337830646 SLPSSSQLKGS(ph)PQAISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLPSSSQLKGSPQAISR 17 1 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 SLPS(0.002)S(0.002)S(0.008)QLKGS(0.988)PQAISR 76.158 0.041047 8523400.0 13537.0 17429.0 12415.0 20666.0 24609.0 23027.0 20541.0 16966.0 19607.0 10669.0 True False 15828.54673206272 19159.23593575177 12711.020684149698 19508.151020075984 19787.04310718464 21819.423583283256 18595.207776038387 16520.660476962905 19893.715282200297 12603.205244242465 1.255914382517391 1.5201875685158983 1.008554604786468 1.5478721993349995 1.5700008627744895 1.7312598787717948 1.4754348132617499 1.3108300751120479 1.5784647553278848 1.0 13.62150306580735 SLPSTSS(ph)TSSTKR ddPTM_PC-9_AZD4547_30min_R2 1 SLPSTSSTSSTKR 13 1 A0A590UJA3;S4R3W2;A0A590UJU2;A0A590UK38;B1AKN5;A0A590UK09;B1AKN8;Q12857-2;Q12857-3;Q12857;Q12857-4;A0A590UK73;B1AKN7 A0A590UJA3 NFIA Nuclear factor 1;Nuclear factor 1 A-type 1 SLPS(0.022)T(0.022)S(0.072)S(0.385)T(0.242)S(0.193)S(0.058)T(0.006)KR 55.413999999999994 0.035508 4274600.0 13839.0 13506.0 16089.0 28407.0 21066.0 13248.0 13101.0 18777.0 13562.0 17099.0 True False 18239.514130918 17871.550375774958 15875.649347634155 21858.205033774964 18141.349525628782 12419.600465716707 14266.963620000075 15875.446102534881 14278.859632628259 16500.369214530532 1.105400363699495 1.0831000290609822 0.9621390370861376 1.3247100564589926 1.0994511268058882 0.7526862159411424 0.8646451139672876 0.9621267194769598 0.8653660682970675 1.0 14.01021068632434 -6.6748606364422765 8.405339852932116 0.8854386461478453 1.1177318148752937 0.5464906130907845 0.10296729399568456 0.2071219043239808 17.844621166001083 0.0345254372233818 0.034478220625911146 2.1141673597971583e-07 6.6748606364422765 0.23229316872744843 SLPTPAVLLS(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 2 SLPTPAVLLSPTK 13 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;A0A3B3ISX8 Q8WX93-3 PALLD Palladin 1 SLPTPAVLLS(0.858)PT(0.142)K;SLPTPAVLLS(0.889)PT(0.111)K 130.47 8.0153e-05 11817200.0 49335.0 55603.0 51210.0 56280.0 68510.0 69571.0 64261.0 77852.0 87740.0 63793.0 True False 65022.50376825197 73575.58237407194 50530.921939980435 43305.5155173322 58998.569068680685 65220.714372009206 69980.10450994768 65821.76226098661 92377.75727523991 61559.626487077985 1.056252408904737 1.1951921506462717 0.8208451679054195 0.7034726815053448 0.9583971254449555 1.0594722238235108 1.1367857231011178 1.069235893996259 1.5006224460220041 1.0 15.909696857692586 -7.273691492899886 1.5482134629256241 1.2125531390929163 0.9435990812128731 0.2844155147913896 0.17246364501729344 0.5414144041105469 2.5297667086069184 0.1049328705704535 0.062265426462100745 5.3248638402553956e-08 7.273691492899886 -0.26895405788004323 SLPTPAVLLS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLPTPAVLLSPTK 13 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;A0A3B3ISX8 Q8WX93-3 PALLD Palladin 1 SLPTPAVLLS(1)PTK;SLPTPAVLLS(0.999)PT(0.001)K 151.07 0.00013144 7710500.0 42216.0 68611.0 51862.0 52277.0 63192.0 47309.0 61100.0 48928.0 44820.0 47946.0 True False 49362.33499599315 75422.24664569761 53098.58676773026 49348.08917432077 50809.98122756757 44828.03275726526 55312.16567430725 47643.69184350121 45475.40770889054 56638.23025967284 0.8715373833129771 1.3316490698933303 0.9375043415778679 0.8712858602408919 0.8970969077708797 0.7914801107262598 0.9765871112270652 0.8411931591977043 0.802910110368855 1.0 15.78948856666029 -5.503141698491059 23.81158520325897 0.8791079414245304 1.109839168324789 0.33776711840762497 0.1205866975642822 378.25946192181505 456345.938806567 0.029082650437861422 0.059107748758939684 3.139484198348556e-06 5.503141698491059 0.2307312269002586 SLPTPAVLLS(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 1 SLPTPAVLLSPTK 13 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;A0A3B3ISX8 Q8WX93-3 PALLD Palladin 1 SLPTPAVLLS(1)PTK 134.06 4.4916e-05 2890900.0 19895.0 22593.0 18248.0 17435.0 29266.0 28576.0 27059.0 30230.0 24404.0 30920.0 True False 19611.29365170383 22540.68729660977 16747.719879317025 18717.228061455018 27544.63141916981 27353.871093909544 28459.982619296145 31634.59616004072 21655.36453448732 36264.48080168977 0.5407851765187832 0.6215637670334292 0.46182158158835823 0.5161311467220254 0.7595484840882196 0.7542882316030557 0.7847894686519276 0.872330044735307 0.5971508223958433 1.0 15.146269573550203 -6.305934319618642 4.936272620420894 0.7881859065655701 0.5355138427582451 0.6105448316990191 0.10162035288482785 0.14121833984600732 8.214733316367528 0.03033361078943097 0.03528654660600724 4.943854495521878e-07 6.305934319618642 -0.252672063807325 SLPTPAVLLS(ph)PTKEPPPLLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLPTPAVLLSPTKEPPPLLAK 21 1 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;A0A3B3ISX8 Q8WX93-3 PALLD Palladin 1 S(0.001)LPT(0.012)PAVLLS(0.92)PT(0.067)KEPPPLLAK;SLPT(0.019)PAVLLS(0.546)PT(0.434)KEPPPLLAK 76.52600000000001 0.00062286 26285000.0 36856.0 67141.0 52194.0 53656.0 59326.0 54580.0 64937.0 52393.0 53503.0 47085.0 True False 43094.99286081876 73806.31476058922 53438.50290684725 50649.82827509907 47701.49617525441 51717.72871740132 58785.6972568329 51017.739264972166 54285.380157268424 55621.137775345065 0.7747952412422834 1.3269472310813644 0.9607588957041202 0.9106219380062807 0.8576145343865806 0.9298214812917043 1.0568949073690215 0.9172365274337587 0.9759847124402274 1.0 15.763345636029431 -5.488282706711886 24.999081968912353 0.9452872450162405 1.0741166812290774 0.0760843111831564 0.13409806935231694 1138.5340043384952 822702.5995199016 0.0328048762769376 0.06823059117761687 3.248757486359609e-06 5.488282706711886 0.12882943621283693 SLPTPAVLLS(ph)PTKEPPPLLAKPK ddPTM_PC-9_AZD4547_30min_R2 2 SLPTPAVLLSPTKEPPPLLAKPK 23 2 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;A0A3B3ISX8 Q8WX93-3 PALLD Palladin 1 S(0.001)LPT(0.012)PAVLLS(0.8)PT(0.187)KEPPPLLAKPK;SLPT(0.002)PAVLLS(0.79)PT(0.208)KEPPPLLAKPK 60.669 0.0015772 55961000.0 94724.0 73357.0 103698.0 141286.0 133658.0 137497.0 99300.0 126031.0 114876.0 138818.0 True False 124844.26161840245 97068.21567567922 102322.89676493056 108714.69554694036 115101.89380501746 128899.290854065 108137.50763041058 106555.80485426683 120948.110835998 133958.02407291092 0.9319655353415185 0.7246166576990323 0.7638429834500848 0.8115579212169398 0.8592385159575778 0.9622364300021883 0.8072491989845513 0.7954417482021864 0.9028806723079772 1.0 17.03142147550124 -6.277071272146944 3.879261366322395 0.8783344187449998 0.7977380221117727 0.1990761519317964 0.0768686504404136 0.38938679661124953 13.402434888190575 0.0241308957191287 0.02926454197387988 5.283585356438481e-07 6.277071272146944 -0.08059639663322715 SLPTPAVLLS(ph)PTKEPPPLLAKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLPTPAVLLSPTKEPPPLLAKPK 23 2 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;A0A3B3ISX8 Q8WX93-3 PALLD Palladin 1 S(0.001)LPT(0.011)PAVLLS(0.742)PT(0.245)KEPPPLLAKPK;SLPTPAVLLS(0.832)PT(0.168)KEPPPLLAKPK 61.684 0.0012978 15367580.0 31845.4 26676.1 30157.9 35535.0 47863.2 44250.2 51522.5 49194.4 53457.7 46963.2 True False 37236.19724467974 29324.326911796903 30876.97871047265 33544.08915602441 38484.74954885608 41929.64161397493 46641.91580940258 47903.09912577531 54239.41773046762 55477.25639951332 0.6711975260010586 0.528582861066903 0.5565700381452808 0.6046457833902306 0.6937031866124096 0.7557987603428558 0.8407394099217161 0.8634727496400768 0.9776874569980256 1.0 15.759608821199977 -7.21142892569125 0.7001006094004802 0.9952168143274878 0.5665711917059555 0.9336693741791185 0.04091898103612954 0.16568189771798036 0.16287823274927044 0.034971551096417294 0.023821543323134107 6.145696006453484e-08 7.21142892569125 -0.4286456226215323 SLPTPAVLLS(ph)PTKEPPPLLAKPK ddPTM_PC-9_Lapatinib_30min_R1 1 SLPTPAVLLSPTKEPPPLLAKPK 23 2 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;A0A3B3ISX8 Q8WX93-3 PALLD Palladin 1 S(0.001)LPT(0.017)PAVLLS(0.792)PT(0.19)KEPPPLLAKPK 50.498000000000005 0.0097091 9467800.0 20706.0 15433.0 16110.0 13250.0 19874.0 17191.0 15299.0 16909.0 17423.0 18245.0 True False 20410.728642984646 15397.2658367007 14785.497986398346 14224.44920070426 18705.050393787355 16455.781004178298 16091.107361418086 17694.653869339352 15460.6382676763 21398.623940065652 0.953833699781446 0.7195446716492678 0.6909555505910248 0.6647366316892533 0.8741239832139396 0.7690111780210018 0.7519692577656804 0.826906156157491 0.7225061906307264 1.0 14.385230405209837 -11.389124037179085 2.7215500936184913 1.0989832239777564 0.7711179228744862 0.39311311504563473 0.08381206752217525 17221827.522864696 11702283.869634947 11033188.319841785 0.02149142648226339 4.082027844527965e-12 11.389124037179085 -0.32786530110327017 SLPTPAVLLSPT(ph)KEPPPLLAKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLPTPAVLLSPTKEPPPLLAKPK 23 2 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;A0A3B3ISX8 Q8WX93-3 PALLD Palladin 1 SLPTPAVLLS(0.206)PT(0.794)KEPPPLLAKPK 73.44800000000001 0.00025231 10099000.0 56959.0 49069.0 49212.0 79201.0 76807.0 79596.0 92798.0 92629.0 82614.0 69734.0 True False 66601.03370847007 53940.24603427644 50385.40071754933 74763.62474310654 61757.219713662926 75421.84563925011 84007.50164066085 90197.58689853825 83822.07345966728 82376.22218595972 0.8084982770649759 0.6548035901975372 0.6116498108374903 0.907587441608233 0.7496971586564076 0.9155778650420446 1.0198027951684723 1.094946873078523 1.0175518036071578 1.0 16.32994034456899 -6.829630956941185 1.1166771556787412 1.054078657214247 0.7133149583353423 0.7443978116663394 0.07927500162791179 0.23669191476884927 0.6232549039207563 0.04397421179322813 0.03714843453043614 1.480365799195033e-07 6.829630956941185 -0.3407636988789048 SLPTPAVLLSPT(ph)KEPPPLLAKPK ddPTM_PC-9_Lapatinib_30min_R1 1 SLPTPAVLLSPTKEPPPLLAKPK 23 2 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;A0A3B3ISX8 Q8WX93-3 PALLD Palladin 1 SLPTPAVLLS(0.16)PT(0.84)KEPPPLLAKPK 85.087 1.6254e-05 915900.0 4640.1 3026.9 3948.5 4061.9 5140.5 3402.6 3387.4 3834.6 5130.7 3361.4 True False 4573.931323109873 3019.8913990221827 3623.86957165077 4360.62567610118 4838.145896611847 3257.078729848005 3562.7829973245075 4012.7695148955395 4552.8265373338045 3942.4135112160425 1.1601855843120419 0.7660006720326741 0.9192007792538694 1.1060802383350548 1.2272040674697047 0.8261636483797852 0.9037060641123773 1.0178459219154299 1.1548323189287872 1.0 11.944863390138652 -5.732544196547547 24.833278773177916 1.0284340415769626 0.9302160860320071 0.0660358997674928 0.1410248166630917 529.8703377414024 455380.2503582735 0.03944867551990879 0.06831176236755512 1.851210493755185e-06 5.732544196547547 -0.0982179555449555 SLPTPAVLLSPTKEPPPLLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLPTPAVLLSPTKEPPPLLAK 21 1 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;A0A3B3ISX8 Q8WX93-3 PALLD Palladin 0 180.62 6.9977e-13 1060300.0 9327.1 12645.0 11730.0 14236.0 13804.0 9657.0 15722.0 13310.0 12001.0 12468.0 False True 10905.993811377864 13900.312032106325 12009.687686272726 13438.403073734722 11099.205292843131 9150.569919823094 14232.698342577069 12960.626603110719 12176.49192133859 14728.349703366304 0.7404762944272837 0.9437793311581457 0.8154129911464417 0.9124174360596047 0.753594633233505 0.6212895608889327 0.9663471216550521 0.879978196073688 0.8267383764357209 1.0 13.846308166464166 -9.160336803936504 0.6908182051936821 1.0025233607039243 0.822043196676321 0.21894376368690394 0.09873038918592682 3.745176957020022 2.662783962892983 0.13324991903482514 0.038135246528479765 6.912946503461623e-10 9.160336803936504 -0.18048016402760336 SLPTPAVLLSPTKEPPPLLAKPK ddPTM_PC-9_AZD4547_30min_R2 3 SLPTPAVLLSPTKEPPPLLAKPK 23 2 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;A0A3B3ISX8 Q8WX93-3 PALLD Palladin 0 ;; 115.57 1.2806e-07 3981800.0 17707.5 14037.100000000002 17523.9 26743.9 25319.9 21573.899999999998 20503.6 20111.5 18190.5 24411.899999999998 False True 23338.11666111932 18574.31806454841 17291.521636087138 20578.507044136117 21804.66893828767 20224.880622533652 22328.38067926369 17003.729791294154 19152.012693358225 23557.246811404057 0.9906979728132467 0.7884757592112415 0.7340213300187659 0.8735531451907218 0.9256034507280382 0.8585417805591269 0.9478349001486255 0.7218046288440911 0.8129987704712055 1.0 14.523883317544906 -4.747047187706742 24.91670127422128 0.845308144856712 0.9906983625286383 0.1883542699248194 0.08589135491242184 1250.3536205019318 2164565.8783569485 0.02151687627920542 0.4567588742647613 1.790411308635128e-05 4.747047187706742 0.14539021767192628 SLPTPAVLLSPTKEPPPLLAKPK ddPTM_PC-9_Lapatinib_30min_R1 2 SLPTPAVLLSPTKEPPPLLAKPK 23 2 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;A0A3B3ISX8 Q8WX93-3 PALLD Palladin 0 ; 118.15 9.3213e-08 2162300.0 8460.1 5622.299999999999 5317.2 5703.3 7778.8 9440.9 6528.200000000001 6359.9 6496.700000000001 5756.7 False True 8339.457422607667 5609.28190978308 4880.040340985559 6122.739707651069 7321.266277709217 9037.134714812799 6866.198253272077 6655.40417195643 5764.973232716106 6751.737924679412 1.2351571574075344 0.8307908233937297 0.7227828442729839 0.9068390651347432 1.0843528524630712 1.3384901510734961 1.0169527208949094 0.9857320065148181 0.8538502674464873 1.0 12.721043190172926 -4.738782977928255 24.73042742138217 0.9773288212335496 1.2351583489592668 0.19942859314737882 0.1582811179782312 3312.213669826766 3615209.158796781 0.044525849857832527 2.350615234044494 1.824807352262942e-05 4.738782977928255 0.2578295277257172 SLPTT(ph)VPESPNYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLPTTVPESPNYR 13 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YC33 Q6PKG0 LARP1 La-related protein 1 1 S(0.236)LPT(0.072)T(0.353)VPES(0.34)PNYR 103.14 0.003849 164620000.0 13182.0 13478.0 19018.0 16191.0 16617.0 16550.0 21495.0 16148.0 17642.0 11758.0 True False 15413.452243632311 14816.006767001114 19471.461246166644 15283.870761930242 13361.018136132589 15682.088865390107 19458.83798967651 15724.132110220267 17899.980874615063 13889.63232372321 1.1097091617973536 1.0666953898913274 1.4018701713874588 1.1003797944907225 0.9619418156456339 1.1290499633028743 1.4009613455671688 1.1320769149060748 1.288729640743784 1.0 13.761720789397057 SLPTTVPES(ph)PNYR ddPTM_PC-9_AZD4547_30min_R2 6 SLPTTVPESPNYR 13 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YC33 Q6PKG0 LARP1 La-related protein 1 1 SLPTTVPES(1)PNYR;SLPTTVPES(1)PNYR;SLPTTVPES(1)PNYR;SLPTTVPES(1)PNYR;SLPTTVPES(1)PNYR;SLPTTVPES(1)PNYR 297.45 8.289499999999998e-98 1606429700.0 561066.0 624580.0 809809.0 1109505.0 774125.0 735041.0 585400.0 817308.0 565772.0 608079.0 True False 739473.3171022217 826463.2706724063 799070.4035401995 853725.7639313717 666651.1061201649 689078.770072531 637499.4659299336 691011.8284694342 595677.5528735693 586790.3392948431 1.2602002241394439 1.4084473027718598 1.36176475655761 1.4549076676301622 1.1360976169466115 1.174318532409054 1.0864177939535073 1.1776128238577273 1.0151454667597393 1.0 19.162485593631224 -6.33799248151302 5.898858047783218 1.1080780774567378 1.3728173071140823 0.7768110866981935 0.07164351382291487 0.10577572011035312 6.3570152048596285 0.021577480973123907 0.02458069670018916 4.592059625214931e-07 6.33799248151302 0.26473922965734453 SLPTTVPES(ph)PNYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 SLPTTVPESPNYR 13 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YC33 Q6PKG0 LARP1 La-related protein 1 1 SLPT(0.003)T(0.011)VPES(0.941)PNY(0.044)R;SLPTTVPES(1)PNYR;SLPTTVPES(1)PNYR;SLPTTVPES(1)PNYR;SLPTTVPES(1)PNYR;SLPTTVPES(1)PNYR;SLPTTVPES(1)PNYR;SLPTTVPES(1)PNYR 236.05 6.1816e-26 1365703600.0 950194.8 866951.2 985120.5 983486.2 922016.9 606697.0 673282.6 531924.8 552712.6 488432.4 True False 1111044.0124372453 953016.3856551215 1008609.5088102988 928384.656719282 741354.3071986967 574880.7412909721 609504.3979840983 517962.33762091195 560794.9761454915 576981.3276912482 1.925615196046314 1.6517282967692426 1.748079981801459 1.6090376103402697 1.284884400271974 0.99635935116188 1.056367630514126 0.8977107451527128 0.971946489827452 1.0 19.13816510546853 -6.370265978595366 1.4079052523214375 0.9626560484549382 1.7826105621449084 0.9607340874576007 0.07201057554639449 0.07012679402653833 0.28142751922603537 0.02739782399626221 0.034722919011879724 4.263183451300384e-07 6.370265978595366 0.8199545136899702 SLPTTVPES(ph)PNYR ddPTM_PC-9_Lapatinib_30min_R1 7 SLPTTVPESPNYR 13 0 Q6PKG0;Q6PKG0-3;A0A0B4J210;E5RH50;H0YC33 Q6PKG0 LARP1 La-related protein 1 1 SLPTTVPES(1)PNYR;SLPTTVPES(1)PNYR;SLPTTVPES(1)PNYR;SLPTTVPES(1)PNYR;S(0.001)LPT(0.004)T(0.022)VPES(0.971)PNY(0.003)R;SLPTTVPES(1)PNYR;SLPTTVPES(1)PNYR 241.76 8.5488e-27 2104670000.0 740992.0 663277.0 756757.0 577553.0 569348.0 509770.0 475088.0 429507.0 494822.0 351592.4 True False 730425.3181987099 661741.2228581164 694539.360626495 620028.1742803286 535860.0700212354 487968.3254319101 499685.7320165626 449463.4632123915 439089.9356533387 412364.6778725758 1.7713091285292322 1.604747589614356 1.684284318942355 1.503591863103082 1.299481014682884 1.1833417157584396 1.2117568715984197 1.089965962970474 1.0648097647903325 1.0 18.65356123478464 -6.284764907804627 0.673293110412202 1.0447539305160483 1.7763252644554353 0.9622224321109433 0.05134578681008026 0.1495932462979041 0.14543065725272364 0.03403599478883042 0.061545247880027326 5.190809516792112e-07 6.284764907804627 0.731571333939387 SLPVSVPVWGFK ddPTM_PC-9_Lapatinib_30min_R1 1 SLPVSVPVWGFK 12 0 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 0 119.68 0.0025309 0.0 6456.9 4541.4 5282.0 4413.5 5356.7 5344.3 5505.1 5912.3 5336.6 4689.0 False True 6364.82342194956 4530.884667322784 4847.734349109631 4738.083513004396 5041.629437677403 5115.73674717178 5790.127141338828 6187.007041912299 4735.535911110684 5499.487402300234 1.157348486567564 0.8238739969524579 0.881488399642847 0.8615500257392407 0.916745338041628 0.930220650206791 1.0528485143755453 1.1250152222049825 0.8610867822208271 1.0 12.425081438458813 -7.174773904990597 5.819127750944341 1.0198441920277346 0.9171174743904063 0.11939655220208178 0.10420742484096295 0.4066086755445035 21.641432548627822 0.03941233746593305 0.030328085570151108 6.686919500014673e-08 7.174773904990597 -0.10272671763732832 SLQMEGQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLQMEGQK 8 0 A0A0C4DGG5;Q9P2F6-4;Q9P2F6-2;Q9P2F6-3;Q9P2F6 A0A0C4DGG5 ARHGAP20 Rho GTPase-activating protein 20 0 74.301 0.023483 5319300.0 25729.0 11490.0 24163.0 40998.0 40810.0 43433.0 33850.0 37496.0 38430.0 34488.0 False True 30084.411529086312 12630.6512652354 24739.1375586878 38701.01497730935 32813.573457036226 41155.297020573315 30643.482947222612 36511.76973029598 38991.966047582835 40740.4013931422 0.7384417065206038 0.31002765886743344 0.6072384343972643 0.9499419164737012 0.8054307845518603 1.0101838865903012 0.7521644829051882 0.8962054491795453 0.957083502229468 1.0 15.31417257401729 -5.659869719280682 4.639786287390748 0.8987197678650071 0.5104548327147218 0.6393436089149381 0.1236391781350335 0.11845367515923018 4.320313603139927 0.03186076790414284 0.0564378805751918 2.188418012472065e-06 5.659869719280682 -0.38826493515028526 SLQS(ph)VAEER ddPTM_PC-9_Lapatinib_30min_R1 1 SLQSVAEER 9 0 P61313;A0A2R8YEM3;E7EQV9;E7EX53;A0A2R8Y738;P61313-2 P61313 RPL15 60S ribosomal protein L15;Ribosomal protein L15 1 S(0.001)LQS(0.999)VAEER 74.46 0.027395999999999997 1400900.0 10844.0 12407.0 11654.0 10944.0 10153.0 11776.0 9376.0 9610.6 12756.0 7677.5 True False 10689.362571453952 12378.272353783812 10695.853105740935 11748.858268113769 9555.820501566019 11272.36793119676 9861.443402879666 10057.143561220222 11319.28495336504 9004.545645374292 1.187107378032468 1.3746692882991416 1.1878281844498708 1.3047696941987577 1.0612218403795777 1.251853050130016 1.0951627979081398 1.116896282977549 1.2570634209822513 1.0 13.13643776660123 -10.201610120697916 0.029661033676243762 1.5237642103357212e-10 2.136367106518146 0.36240109856643765 0.08828042224538386 513.2719137771808 3.3079372350070675 137.94817542040076 101.42416699420583 6.286224389707836e-11 10.201610120697916 2.13636710636577 SLQSVAEER ddPTM_PC-9_AZD4547_30min_R2 2 SLQSVAEER 9 0 P61313;A0A2R8YEM3;E7EQV9;E7EX53;A0A2R8Y738;P61313-2 P61313 RPL15 60S ribosomal protein L15;Ribosomal protein L15 0 ; 120.31 0.007763600000000001 12255800.0 108408.0 99324.0 129512.0 146694.0 143579.0 146847.0 129281.0 151371.0 121788.0 133992.0 False True 142879.4889735208 131428.54061331795 127794.58625836264 112875.96469970733 123645.53420394282 137664.63387598918 140786.75854951752 127980.09010953839 128225.46504487025 129300.98086399044 1.1050147339857646 1.0164543202620053 0.9883497047310698 0.8729706762119592 0.9562613785119195 1.0646836006665434 1.0888297800123325 0.9897843717377406 0.9916820753258515 1.0 16.980373693763227 -6.755738062848816 24.99808891578348 1.0302221022687832 0.9830515102639064 0.08919782485829653 0.06124600233795634 345.0455083542271 1512891.9587573814 0.022523573716486736 0.021929624235526635 1.7549386433809196e-07 6.755738062848816 -0.04717059200487683 SLQSVAEER ddPTM_PC-9_Lapatinib_30min_R1 3 SLQSVAEER 9 0 P61313;A0A2R8YEM3;E7EQV9;E7EX53;A0A2R8Y738;P61313-2 P61313 RPL15 60S ribosomal protein L15;Ribosomal protein L15 0 ;; 109.44 0.010912999999999999 32182900.0 187771.0 224418.0 220733.0 221736.0 240114.0 229492.0 189170.0 207580.0 243598.0 194793.0 False True 185093.35110701568 223898.37390920133 202585.18479402064 238043.20512961206 225990.96660228694 219677.16213198088 198964.29698408127 217224.92460804677 216161.42803933952 228462.71050464327 0.8101687610121121 0.9800215248021878 0.886731950026056 1.0419346098267275 0.9891809744491931 0.9615449350432012 0.870883027451596 0.9508112905087498 0.9461562789037569 1.0 17.801599183439322 -4.755578396353445 24.983520748987512 0.9557150203608458 0.8101685234044594 0.4597330688215284 0.04817706283157954 182.43661399196267 777591.3011219933 0.01222341888579524 0.10665035737456048 1.755583957629277e-05 4.755578396353445 -0.14554649695638633 SLQTLPT(ph)DSSTFDTDTFCPPRPK ddPTM_PC-9_AZD4547_30min_R2 1 SLQTLPTDSSTFDTDTFCPPRPK 23 1 B0QY95;Q9NQG6 B0QY95 MIEF1 Mitochondrial dynamics protein MID51 1 S(0.094)LQT(0.001)LPT(0.841)DS(0.046)S(0.009)T(0.009)FDTDTFCPPRPK 102.67 2.7194e-06 9123900.0 23705.0 30750.0 34505.0 28497.0 26886.0 28165.0 29992.0 37665.0 31345.0 27633.0 True False 31242.696905369663 40689.336150975854 34047.44115483349 21927.456924261114 23153.342986141448 26403.838097592925 32661.229897797293 31844.739705596006 33001.83270791424 26665.5770808306 1.171649006907466 1.5259124536339654 1.2768312139514721 0.822313233941761 0.8682858396785257 0.9901843870678563 1.224846167731238 1.1942265344217362 1.2376192950138198 1.0 14.702690929870887 -5.540440528461153 23.867177863985148 1.053427330354283 1.3619285265543877 0.40452130699582556 0.15517015953612787 135.32507872050147 183911.23365379995 0.04596302145851776 0.07963774048082772 2.881107556672743e-06 5.540440528461153 0.30850119620010474 SLQTTS(ph)PPVVAPGNENGLAVPVPLRK ddPTM_PC-9_AZD4547_30min_R2 2 SLQTTSPPVVAPGNENGLAVPVPLRK 26 1 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 S(0.003)LQT(0.011)T(0.047)S(0.938)PPVVAPGNENGLAVPVPLRK;S(0.006)LQT(0.067)T(0.183)S(0.745)PPVVAPGNENGLAVPVPLRK 136.27 5.468999999999999e-10 21511100.0 39325.0 35866.0 49580.0 69793.0 54709.0 57492.0 34983.0 61196.0 38101.0 49064.0 True False 51829.53198918633 47458.983102143095 48922.536805003496 53703.30214110106 47113.59969608019 53897.01615149346 38096.419228949126 51739.56434418301 40114.94107526685 47346.28429391934 1.0946905921367682 1.0023803094562633 1.0332920003035293 1.1342664570617245 0.9950854728874884 1.1383578871133384 0.8046337700431083 1.092790387160918 0.8472669328439526 1.0 15.530963587902457 -7.240831892242944 24.98413755551084 0.9439052730198911 1.0617837400428305 0.3494281103184652 0.08662467724136741 939.7931759874783 1139389.4387281088 0.030567986656760204 0.0236509904145096 5.743387356105346e-08 7.240831892242944 0.11787846702293936 SLQTTS(ph)PPVVAPGNENGLAVPVPLRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLQTTSPPVVAPGNENGLAVPVPLRK 26 1 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 SLQT(0.021)T(0.06)S(0.919)PPVVAPGNENGLAVPVPLRK;S(0.043)LQT(0.052)T(0.152)S(0.753)PPVVAPGNENGLAVPVPLRK 140.42 2.7822e-12 10534200.0 64716.0 47039.0 58479.0 63620.0 66326.0 65973.0 64831.0 70147.0 62700.0 38417.0 True False 75671.14060073654 51708.72105007905 59873.361142842514 60055.57765882291 53329.89642517481 62513.2597411711 58689.738344206446 68305.71557689007 63616.86888325382 45381.69799119532 1.667437402087022 1.1394179446549415 1.3193283590767975 1.3233435573625856 1.175141054341368 1.3774993556499262 1.293246858140766 1.5051379432770966 1.4018177304779644 1.0 15.469822969116068 -11.730562039974572 2.222865610404178 0.00011686518125590819 1.3453007606414211 0.35109482882405163 0.14448502612104255 1921755.6713821662 376840.5664862815 9681241.684779089 0.03576486645166764 1.8596788848023376e-12 11.730562039974572 1.3451838954601651 SLQTTS(ph)PPVVAPGNENGLAVPVPLRK ddPTM_PC-9_Lapatinib_30min_R1 2 SLQTTSPPVVAPGNENGLAVPVPLRK 26 1 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 S(0.002)LQT(0.022)T(0.09)S(0.885)PPVVAPGNENGLAVPVPLRK;S(0.007)LQT(0.019)T(0.194)S(0.781)PPVVAPGNENGLAVPVPLRK 98.446 1.5145e-09 11240700.0 50289.0 39595.0 44727.0 35569.0 35858.0 33174.0 32087.0 25243.0 40824.0 24787.9 True False 49571.86963812684 39503.32021020954 41049.718711212874 38184.86291470565 33748.90293954043 31755.225352371064 33748.307857103224 26415.881934102137 36225.97122422189 29072.4554871994 1.7051146457151969 1.358788569737525 1.411979759648684 1.313437832298632 1.1608549183057506 1.0922787504603073 1.1608344493626486 0.908622319354244 1.2460581886580644 1.0 14.827365307562955 -1.5228787498300753 0.30393847477643215 1.0175236055248242 6.762157125059358 0.7940132538785539 0.09808328713980138 22.525691496852648 0.3213315933413247 0.09377776235233036 70.6700842242812 0.02999999968571525 1.5228787498300753 5.744633519534533 SLS(ph)AASCPPISLPAAASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSAASCPPISLPAAASR 18 0 P41250;F8WCK4 P41250 GARS Glycine--tRNA ligase 1 SLS(1)AASCPPISLPAAASR 125.45 4.4313e-05 4450200.0 10443.0 13657.0 16013.0 16674.0 14405.0 16037.0 16945.0 13320.0 15872.0 8187.0 True False 12210.793641348228 15012.776704031327 16394.810649640684 15739.809837837376 11582.443657157735 15195.991488474985 15339.846928823834 12970.364113706593 16104.097973126074 9671.238291743663 1.2625884372813545 1.5523117362176606 1.6952131831594859 1.6274865082452217 1.197617441299701 1.5712560305176024 1.5861305932167407 1.3411275497967405 1.6651536739482622 1.0 13.239484906834095 -11.133719439574488 5.015569466118865 0.9943915473341766 1.5019940736323985 0.45442464068420674 0.16430133958429227 0.010286806397822814 0.000798155008281106 0.15881853027008977 0.038254194424133386 7.349885278872822e-12 11.133719439574488 0.5076025262982219 SLS(ph)AASCPPISLPAAASR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSAASCPPISLPAAASR 18 0 P41250;F8WCK4 P41250 GARS Glycine--tRNA ligase 1 S(0.043)LS(0.737)AAS(0.22)CPPISLPAAASR 170.48 8.8201e-25 0.0 4434.0 6175.2 5618.5 4497.3 4296.3 6277.9 7024.5 5505.0 6391.8 6120.8 True False 4370.770346903985 6160.901703803153 5156.568618037193 4828.046444553003 4043.600080850792 6009.408851499675 7388.194238857525 5760.782396990545 5671.8881753620735 7178.772124546657 0.6088465089954365 0.8582110696531152 0.7183078844925493 0.6725448810450849 0.5632718256962568 0.8371081777274232 1.0291724142621526 0.8024746150239921 0.7900916865668383 1.0 12.809521387580139 -6.968342850182527 12.23081196036108 0.8952807961805234 0.6955876101444568 0.5218887073999925 0.10054654349680632 0.8155792468275599 313.150491176612 0.03629434084245072 0.03197088381139203 1.0756157424288147e-07 6.968342850182527 -0.19969318603606656 SLS(ph)AIDR ddPTM_PC-9_AZD4547_30min_R2 2 SLSAIDR 7 0 O95831-3;O95831;O95831-6;O95831-4 O95831-3 AIFM1 Apoptosis-inducing factor 1, mitochondrial 1 S(0.074)LS(0.926)AIDR;S(0.003)LS(0.997)AIDR 104.2 0.010385 35349000.0 74054.0 56750.0 103283.0 107834.0 85373.0 72226.0 87993.0 109700.0 83261.0 82763.0 True False 97601.63158111127 75093.32769326442 101913.3999360866 82974.53731869225 73520.43259524847 67709.69680229877 95824.20653497173 92748.3856552207 87662.00647929966 79865.49256109654 1.2220751221993242 0.9402474746627093 1.2760629987741396 1.0389285116499758 0.920553173061643 0.8477966469749288 1.199819890444761 1.1613073767030089 1.097620557617407 1.0 16.285284672884913 -4.728112894342517 24.167435435018355 1.0591087193845017 1.2220768949541976 0.13591726473533938 0.1267580526070684 7690.542499209663 5576474.963670015 0.033138237749230096 5.47683935459556 1.8701959219305012e-05 4.728112894342517 0.1629681755696959 SLS(ph)AIDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSAIDR 7 0 O95831-3;O95831;O95831-6;O95831-4 O95831-3 AIFM1 Apoptosis-inducing factor 1, mitochondrial 1 S(0.014)LS(0.986)AIDR 85.86200000000001 0.019 14754000.0 51463.0 48682.0 52412.0 49442.0 57979.0 42940.0 53044.0 43954.0 41133.0 39217.0 True False 60174.66945941816 53514.82723187034 53661.700853616865 46671.925033126725 46618.43115573396 40688.15080845019 48019.28831469647 42800.25407311259 41734.492309009256 46326.7316583988 1.2989189460445953 1.155160861044001 1.1583312470498504 1.0074512783952319 1.0062965697534219 0.8782866684503878 1.0365352053923884 0.9238781269680423 0.9008727966554706 1.0 15.499557283665832 -5.359130968530084 0.824380108948768 0.9438495927100803 1.3356078331451835 0.8299299226744761 0.05167056225818942 0.4678874959105564 0.4249360848869255 0.020627443066991494 0.14392937485976479 4.373901831787401e-06 5.359130968530084 0.3917582404351032 SLS(ph)AIDR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSAIDR 7 0 O95831-3;O95831;O95831-6;O95831-4 O95831-3 AIFM1 Apoptosis-inducing factor 1, mitochondrial 1 S(0.001)LS(0.999)AIDR 88.177 0.017446 10405000.0 54964.0 46379.0 24702.0 20441.0 23235.0 21205.0 18900.0 14878.0 31572.0 18150.0 True False 54180.20328083686 46271.612275017294 22671.096912477464 21944.29932917704 21868.362981767583 20298.111581269306 19878.54952158976 15569.286194809334 28016.028892101054 21287.203316645202 2.5452006294538223 2.1736820749410475 1.0650105875932583 1.0308681231046462 1.0273008932398344 0.953535853410932 0.9338262629382618 0.7313918114661483 1.3160972099230315 1.0 14.377698802508469 -5.194839214634769 2.8516518247672904 0.9820238490319505 2.5080457609361195 0.9400974643639284 0.13798731909448048 0.055482719395102874 0.862902091529442 0.03595060836419341 0.12360759618548045 6.384998291124304e-06 5.194839214634769 1.5260219119041691 up SLS(ph)APGNLLTK ddPTM_PC-9_AZD4547_30min_R2 1 SLSAPGNLLTK 11 0 F5GZ00;Q96RR4-6;Q96RR4-5;Q96RR4-2;Q96RR4-3;Q96RR4-4;Q96RR4-7;Q96RR4 F5GZ00 CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 1 S(0.063)LS(0.937)APGNLLTK 89.23100000000001 0.0093955 9995900.0 23589.0 27004.0 31740.0 41023.0 34673.0 24638.0 27704.0 33323.0 27604.0 28351.0 True False 31089.81131831955 35732.51490799842 31319.10686145241 31565.781149031947 29859.25244954555 23097.38196515161 30169.602330240585 28173.696036362027 29063.091085317083 27358.4401193728 1.1363883022082288 1.3060874359827206 1.1447694651010099 1.1537858522379674 1.0914091709637312 0.8442506906231145 1.1027530151061928 1.0297990643264758 1.0623080467492443 1.0 14.739698354795197 -6.257259290516591 2.3822312271192216 1.0135102540661927 1.2006637162793972 0.531005650410024 0.07774615476583811 0.23588221488000738 2.6365856632980287 0.025736639088027136 0.03288799392308316 5.530198365111546e-07 6.257259290516591 0.1871534622132045 SLS(ph)APGNLLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSAPGNLLTK 11 0 F5GZ00;Q96RR4-6;Q96RR4-5;Q96RR4-2;Q96RR4-3;Q96RR4-4;Q96RR4-7;Q96RR4 F5GZ00 CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 1 S(0.059)LS(0.941)APGNLLTK;S(0.003)LS(0.996)APGNLLTK 111.72 0.0017772999999999999 14703300.0 51688.0 49787.0 54903.0 62561.0 57488.0 57472.0 48787.0 63596.0 51257.0 40860.0 True False 60437.75751546554 54729.52432917974 56212.095740787 59055.90999549862 46223.639081061 54458.06714632626 44165.54217270753 61926.67238553182 52006.53665628298 48267.59455241797 1.2521394131176546 1.1338771868928375 1.1645928549379316 1.2235105259153671 0.9576536703287076 1.1282531821051394 0.9150143607165743 1.282986503880575 1.0774627809514015 1.0 15.558767310459388 -6.234113018837523 24.981193232784054 1.0705182562685094 1.1872021492261795 0.2964829975682032 0.09965284590226317 1086.0111684612891 992809.1554811514 0.028890321332105152 0.037287825212010205 5.832932909053191e-07 6.234113018837523 0.11668389295767012 SLS(ph)APGNLLTK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSAPGNLLTK 11 0 F5GZ00;Q96RR4-6;Q96RR4-5;Q96RR4-2;Q96RR4-3;Q96RR4-4;Q96RR4-7;Q96RR4 F5GZ00 CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 1 SLS(1)APGNLLTK 128.76 0.00029352 8840400.0 49245.0 39318.0 39554.0 36201.0 41384.0 42942.0 36923.0 32939.0 44879.0 37407.0 True False 48542.75726957302 39226.96158669073 36302.02280285538 38863.34230299584 38949.87448407444 41105.47076269121 38834.692274373505 34469.46618973144 39824.25442317887 43872.75010830559 1.1064443680813012 0.8941076520130121 0.827438961843949 0.8858196080039803 0.8877919525883745 0.936924871616596 0.885166582411748 0.7856691478113198 0.9077218620867741 1.0 15.421037522269957 -4.763270441989491 5.6401394449127125 0.8818434907586877 1.1162928616240655 0.5819030543955652 0.054718522946301876 0.09577124781647128 10.218129809011783 0.013204015816346983 0.08744138098466463 1.7247635201991937e-05 4.763270441989491 0.23444937086537776 SLS(ph)APLHPEFEEVYR ddPTM_PC-9_AZD4547_30min_R2 2 SLSAPLHPEFEEVYR 15 0 Q53HC0-2;Q53HC0 Q53HC0-2 CCDC92 Coiled-coil domain-containing protein 92 1 S(0.266)LS(0.734)APLHPEFEEVYR;S(0.17)LS(0.83)APLHPEFEEVYR 89.344 0.0025864 4462900.0 24528.0 32459.0 36954.0 52807.0 46007.0 43275.0 30643.0 48006.0 33075.0 36651.0 True False 32327.393785906235 42950.73697965938 36463.96581468534 40633.16201001706 39619.72218862637 40569.00740895915 33370.16763664317 40587.775768135994 34823.27697604921 35367.85964569616 0.9140330828540847 1.2144002325819556 1.030991588972859 1.148872519204357 1.120218259898224 1.147058595441353 0.9435167400836458 1.1475892568770425 0.9846023289194651 1.0 15.110151293754454 -8.284304099399455 24.106426554694057 0.9923010961898399 1.0868366264198885 0.1380277690968167 0.0906596369662508 1070.5731601833818 1128695.411719852 0.0807859423581964 0.02092745984025365 5.196320151173853e-09 8.284304099399455 0.09453553023004868 SLS(ph)APLHPEFEEVYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSAPLHPEFEEVYR 15 0 Q53HC0-2;Q53HC0 Q53HC0-2 CCDC92 Coiled-coil domain-containing protein 92 1 S(0.331)LS(0.669)APLHPEFEEVYR 86.45299999999999 0.0031013 2852300.0 21467.0 26032.0 20106.0 27724.0 26431.0 20150.0 23104.0 19047.0 19173.0 18236.0 True False 25100.939107423383 28616.284920505488 20585.403292429608 26170.714162420725 21252.035286521063 19093.298527952313 20915.421861525283 18547.03643196467 19453.368853247615 21542.04244390342 1.1652070212370766 1.3283923748188573 0.9555919939362783 1.21486689252287 0.9865376201844578 0.8863272170070334 0.9709117376400176 0.8609692641847726 0.9030419888877845 1.0 14.394867420703562 -6.0506002985901235 0.8575248154464384 0.9077790254041199 1.2307270001815966 0.5714169369139597 0.09678472408839665 0.4653287178967928 0.6990747785759964 0.04492007648623165 0.09795711677792496 8.90019867710697e-07 6.0506002985901235 0.3229479747774767 SLS(ph)APLHPEFEEVYR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSAPLHPEFEEVYR 15 0 Q53HC0-2;Q53HC0 Q53HC0-2 CCDC92 Coiled-coil domain-containing protein 92 1 S(0.49)LS(0.51)APLHPEFEEVYR 58.848 0.032364 4256300.0 14414.0 10927.0 11647.0 8934.5 8281.2 13087.0 11818.0 14007.0 13630.0 11626.0 True False 14208.453716796137 10901.699202852873 10689.428618720149 9591.57293461828 7794.116097465625 12527.299517287038 12429.878214081898 14657.816355067493 12094.845869737022 13635.538609328762 1.0420163166180627 0.7995063132595635 0.7839388618948261 0.7034245737866343 0.5716030969347464 0.9187242159042018 0.9115795547363263 1.0749715706161647 0.8870090295855513 1.0 13.73508406796988 -6.980603713381405 24.99521793981997 0.9661397484308919 0.7739331859957752 0.36609557129089254 0.11864272426307147 268.5934073014122 346124.4878257614 0.0436328916210549 0.03847571559772608 1.0456739444138172e-07 6.980603713381405 -0.1922065624351167 SLS(ph)ASPALGSTK ddPTM_PC-9_AZD4547_30min_R2 2 SLSASPALGSTK 12 0 O95544;O95544-2 O95544 NADK NAD kinase 1 S(0.45)LS(0.545)AS(0.005)PALGSTK;S(0.001)LS(0.998)AS(0.001)PALGSTK 135.02 5.913100000000001e-05 17914500.0 81890.0 76697.0 81994.0 109675.0 91990.0 93045.0 78916.0 92986.0 92017.0 86341.0 True False 107929.31658218602 101487.80535841935 80906.70598607218 84391.12321185872 79218.77636298264 87226.88144116949 85939.37111945079 78617.15030570957 96880.83076357143 83318.22787015518 1.2953866079627288 1.2180744592477413 0.9710564909296778 1.0128770782712224 0.9507976632248922 1.0469123464448336 1.0314594215011443 0.9435768416513627 1.162780741262914 1.0 16.346344533976882 -5.1441957493762205 4.007607479807163 1.0124291463428194 1.2793764677848218 0.7284173827704599 0.05965737296092805 0.10650211392448845 2.8893528969180577 0.014702884851376993 0.045149240198508 7.174708330422729e-06 5.1441957493762205 0.2669473214420024 SLS(ph)ASPALGSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSASPALGSTK 12 0 O95544;O95544-2 O95544 NADK NAD kinase 1 S(0.045)LS(0.909)AS(0.045)PALGSTK;S(0.172)LS(0.828)ASPALGSTK 108.72 0.0013987000000000001 10143300.0 54833.0 63085.0 57372.0 61026.0 71321.0 74072.0 61572.0 44835.0 59282.0 56495.0 True False 64115.14389888412 69347.66188575947 58739.966064521665 57606.911068961446 57346.16203208242 70187.53392369639 55739.45441732321 43658.12875660926 60148.88709947455 66737.09628582606 0.9607122195470946 1.0391171588999424 0.8801696407788892 0.8631917520390571 0.8592846441277049 1.0517019443443054 0.8352094639928381 0.6541808257528516 0.9012811531665225 1.0 16.026201296139018 -7.493739039545944 24.546637024144125 0.8155776317805565 0.9371336295816064 0.142256702010794 0.10308291962827933 809.9172865462751 682258.4237422768 0.042762151565525 0.028767842081148326 3.2081964982700696e-08 7.493739039545944 0.12155599780104986 SLS(ph)ASPALGSTK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSASPALGSTK 12 0 O95544;O95544-2 O95544 NADK NAD kinase 1 SLS(1)ASPALGSTK 97.463 0.0039631 4674800.0 45115.0 44327.0 38672.0 38034.0 40283.0 45185.0 35681.0 36830.0 38328.0 31471.0 True False 44471.65182692226 44224.363554942785 35492.53743823693 40831.14723770461 37913.63313942516 43252.5428813796 37528.38759152614 38541.256254525295 34011.0970282671 36910.72041752843 1.2048437777389802 1.1981441449715298 0.9615780195225335 1.106213771387524 1.027171312576724 1.171815190603528 1.0167340861140275 1.0441751290289785 0.9214422434333106 1.0 15.171752275698474 -1.5228787452803376 0.44255861387109535 1.0205671091892679 5.310232742774609 0.42112498716939506 0.07222575520018136 88.43323538255925 1.0828338279090026 0.046478675022014616 341.13817957026913 0.029999999999999995 1.5228787452803376 4.289665633585341 SLS(ph)CLSDLDGGVALEPR ddPTM_PC-9_AZD4547_30min_R2 1 SLSCLSDLDGGVALEPR 17 0 O95685 O95685 PPP1R3D Protein phosphatase 1 regulatory subunit 3D 1 S(0.015)LS(0.984)CLS(0.001)DLDGGVALEPR 105.5 0.00071817 5876600.0 4916.5 4437.3 6397.8 6953.6 6965.2 5297.2 8886.2 11289.0 6169.1 6199.3 True False 6479.844730447167 5871.570448869113 6312.960991751743 5350.554952049061 5998.202208103564 4965.965246602852 9677.054585149577 9544.544445412806 6495.186031532736 5982.264393920064 1.083175918642581 0.9814963134756376 1.055279502217885 0.8944029550895433 1.0026641774976877 0.8301146388063182 1.617624021262689 1.5954735225532966 1.0857403825437684 1.0 12.546475958303585 -7.2527614055273 24.952109164374182 1.3743322799182816 0.9761474275831101 0.42941543747921385 0.19441214420964836 516.4194948739122 1484883.458046126 0.07337379933425683 0.05591988130121175 5.587770936637735e-08 7.2527614055273 -0.3981848523351714 SLS(ph)CLSDLDGGVALEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSCLSDLDGGVALEPR 17 0 O95685 O95685 PPP1R3D Protein phosphatase 1 regulatory subunit 3D 1 S(0.013)LS(0.882)CLS(0.105)DLDGGVALEPR 105.0 0.00075129 4169100.0 4415.8 3732.8 3683.3 5881.9 6171.0 5638.5 6455.0 4342.0 5569.8 4163.6 True False 5163.307723974481 4103.367714784223 3771.123840993039 5552.356212377091 4961.836848894157 5342.80713398804 5843.535669847027 4228.027100729281 5651.247787973638 4918.427720960537 1.0497882691190834 0.8342844395775448 0.766733609791985 1.1288884430922879 1.0088258139381872 1.0862835517982612 1.1880901786853588 0.8596298127368994 1.148994782192303 1.0 12.263981486061459 -5.769620501249686 24.999809085163974 1.0585402991739652 0.87867033087038 0.35263936227114556 0.109512085862169 186.91379074685153 571170.9016929755 0.030068819802050503 0.04547011649840451 1.699728274154435e-06 5.769620501249686 -0.17986996830358515 SLS(ph)CLSDLDGGVALEPR ddPTM_PC-9_Lapatinib_30min_R1 2 SLSCLSDLDGGVALEPR 17 0 O95685 O95685 PPP1R3D Protein phosphatase 1 regulatory subunit 3D 1 S(0.04)LS(0.96)CLSDLDGGVALEPR;S(0.011)LS(0.978)CLS(0.011)DLDGGVALEPR 228.99 3.0084e-29 6682600.0 12296.2 11446.4 13793.5 12280.8 12329.5 10713.9 12809.1 9568.0 13486.3 9271.0 True False 12120.853933153096 11419.896564064722 12659.451674449758 13183.970999547844 11604.303050729653 10255.691472320734 13472.29252259236 10012.564209701277 11967.33087696511 10873.479997169012 1.1147170856348516 1.0502522253260203 1.1642502379868944 1.2124886423647614 1.0672115140461855 0.9431839185790452 1.2390046724783572 0.9208242634656172 1.1005980495739074 1.0 13.408526120390176 -6.505063663331806 24.564878453621077 1.0433920630714297 1.1324579596639024 0.19484689446176395 0.09108919102452076 1053.5921682115581 1452779.440418459 0.027810271272681396 0.030870774344909896 3.125621147989107e-07 6.505063663331806 0.08906589659247266 SLS(ph)DPIPQR ddPTM_PC-9_AZD4547_30min_R2 2 SLSDPIPQR 9 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 S(0.003)LS(0.997)DPIPQR;S(0.198)LS(0.802)DPIPQR 89.561 0.0092508 4499600.0 42025.0 36445.0 57130.0 78860.0 69936.0 55396.0 45166.0 72854.0 49408.0 57820.0 True False 55388.07582569759 48225.133529180974 56372.4188719211 60680.045374854555 60226.59358323251 51932.07936283535 49185.68650186421 61596.08831837233 52019.60601156883 55795.73939903829 0.9926936433187992 0.8643156995247596 1.010335546747728 1.0875390491894878 1.07941205245988 0.9307534934061733 0.8815312249937132 1.103956842974179 0.9323221911181528 1.0 15.767867340626177 -5.298311528581872 24.126921134918245 1.0057408705673692 0.9285046356759483 0.13587434042664248 0.07516696601061555 652.0646337162613 426670.8759758485 0.02025268977733956 0.04216178601373859 5.031395667001678e-06 5.298311528581872 -0.07723623489142084 SLS(ph)DPIPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSDPIPQR 9 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 S(0.03)LS(0.97)DPIPQR 83.883 0.013669999999999998 1895400.0 32759.0 33785.0 37957.0 37060.0 39452.0 37015.0 34671.0 33365.0 29432.0 25654.0 True False 38304.45168025725 37138.9515227135 38862.0388327241 34983.6483501411 31721.663808551682 35073.8682388166 31386.71188369733 32489.20410313965 29862.38732012644 30304.86712304775 1.2639702898128062 1.225511115819024 1.282369550571907 1.154390422109292 1.046751456779245 1.1573674979799493 1.0356987132217719 1.0720787512851575 0.9853990515409721 1.0 14.887261896362759 -6.16407694553128 0.4992549141889139 1.002829449832417 1.3123780341293696 0.8155497946238566 0.044639437709542734 0.5918130014722459 0.2750623358253594 0.03701060991409699 0.09257446643739066 6.853667867712712e-07 6.16407694553128 0.30954858429695253 SLS(ph)DPIPQR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSDPIPQR 9 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 S(0.004)LS(0.996)DPIPQR 118.03 0.00047284 0.0 18269.0 17642.0 19218.0 14200.0 20664.0 15905.0 16516.0 16127.0 17845.0 16234.0 True False 18008.48070987572 17601.15103292125 17637.970223625296 15244.315369811362 19448.5841469871 15224.780226365874 17371.117666591344 16876.319294508 15835.108183819304 19040.02526955472 0.9458223114163374 0.9244289744229357 0.9263627528808309 0.8006457530383243 1.0214578957563503 0.7996197489669575 0.9123474060913153 0.8863601311230129 0.8316747462063443 1.0 14.21674777291364 -5.55390895958494 24.998911503165406 0.8885811873169789 0.9326934438968988 0.0585408062002204 0.07054496969001944 507.8819430744828 409163.51940413855 0.01784415902285996 0.03090721993184973 2.7931292988247435e-06 5.55390895958494 0.044112256579919906 SLS(ph)DSESDDSK ddPTM_PC-9_AZD4547_30min_R2 4 SLSDSESDDSK 11 0 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 S(0.05)LS(0.941)DS(0.009)ESDDSK;S(0.039)LS(0.956)DS(0.004)ESDDSK;SLS(0.682)DS(0.318)ESDDSK;SLS(0.996)DS(0.003)ES(0.001)DDSK 241.35 5.652999999999999e-20 791240000.0 552654.0 643596.0 570201.0 630624.0 659174.0 598813.0 550441.0 636721.0 590301.0 595440.0 True False 728386.4760826885 851625.8207942585 562639.7621772852 485243.37984367675 567659.0682714733 561369.1284478572 599429.1826544893 538330.399843006 621503.1057366233 574593.8268378313 1.2676545449352041 1.4821353467735991 0.979195626367354 0.8444980735594083 0.987931024938917 0.9769842664987306 1.0432224549876121 0.9368885892937726 1.0816390234419127 1.0 19.132182967762716 -5.271285751243202 24.99887141618118 0.9764500410615705 1.3748949448376702 0.8097462566249177 0.07628562435989542 223.6861758880784 567915.5830448797 0.019342140055944833 0.0410551186293304 5.354442371866498e-06 5.271285751243202 0.39844490377609965 SLS(ph)DSESDDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SLSDSESDDSK 11 0 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 S(0.009)LS(0.895)DS(0.086)ES(0.008)DDS(0.003)K;SLS(0.627)DS(0.373)ESDDSK;S(0.01)LS(0.989)DS(0.001)ESDDSK;SLS(1)DSESDDSK;S(0.018)LS(0.982)DSESDDSK;S(0.002)LS(0.956)DS(0.026)ES(0.015)DDSK 168.98 0.00021334 112429800.0 174517.0 196076.0 159068.0 195118.0 217480.0 164147.0 214606.0 160607.0 162486.0 132177.0 True False 204059.2812321336 215541.12945885936 162860.78438874945 184186.17104109086 174866.35519324275 155538.84235572146 194276.9660671097 156391.236427183 164862.050356689 156139.64378744402 1.30690243862682 1.3804382041006815 1.0430457021565585 1.179624639670801 1.1199356611271112 0.9961521531806461 1.2442513723906197 1.001611330944763 1.0558628568483157 1.0 17.252477357903693 -1.5228787456035315 0.36068673729314876 1.0432612100777148 5.1470702993496005 0.5231101870960475 0.0910691225616194 49.28873172580904 0.6875288329495167 0.07215274698489715 138.95485986875613 0.029999999977674552 1.5228787456035315 4.103809089271886 SLS(ph)DSESDDSK ddPTM_PC-9_Lapatinib_30min_R1 2 SLSDSESDDSK 11 0 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 S(0.46)LS(0.463)DS(0.075)ES(0.001)DDSK;S(0.004)LS(0.633)DS(0.361)ES(0.002)DDSK 171.26 0.00021400000000000002 78154000.0 47303.0 57187.0 59951.0 53678.0 62571.0 57716.0 56410.0 54219.0 58127.0 46416.0 True False 46628.45054569218 57054.58701505884 55022.0601975523 57625.659184558775 58890.69679931913 55247.62122256728 59330.63378375017 56738.212676190815 51580.12515555422 54438.94375456768 0.8565274659977187 1.0480472815983264 1.0107113842181352 1.0585374221138102 1.0817751546543908 1.0148547604385096 1.0898564463564202 1.0422357371955846 0.9474857812836681 1.0 15.73235145493599 -4.7592742928986524 24.99759956892204 1.036827596468049 0.8565272342806605 0.6347975515493129 0.03995232848098102 35.66415645862833 411672.4565416222 0.009788485029948914 0.06286653549978181 1.740707125562179e-05 4.7592742928986524 -0.18030036218738843 SLS(ph)DSESDDSKSK ddPTM_PC-9_AZD4547_30min_R2 4 SLSDSESDDSKSK 13 1 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 SLS(0.989)DS(0.011)ESDDSKSK;SLS(0.927)DS(0.062)ES(0.011)DDSKSK;S(0.002)LS(0.604)DS(0.368)ES(0.026)DDSKSK;S(0.101)LS(0.871)DS(0.016)ES(0.009)DDS(0.001)KS(0.001)K 185.32 4.3457e-12 95228000.0 463611.0 408946.0 451295.0 770580.0 697460.0 594561.0 561326.0 556223.0 534504.0 540682.0 True False 611029.6542921464 541129.7971251053 445310.5334290851 592934.6863423213 600629.7180359369 557383.0066800265 611282.9265674498 470271.51608298667 562756.7902284564 521752.88775079284 1.1711092906954743 1.037138097036403 0.8534893507705524 1.1364281832696388 1.1511766051265602 1.0682892606168992 1.1715947164233418 0.9013299727199681 1.0785887408394152 1.0 18.993007154742322 -7.762660363879426 24.99998795493751 0.9924695484261552 1.0774691468916024 0.1530610172275294 0.09705387639377375 70.72764096781259 1448043.9535058276 0.051450900465609434 0.026881075172898835 1.7271880959876025e-08 7.762660363879426 0.08499959846544725 SLS(ph)DSESDDSKSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLSDSESDDSKSK 13 1 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 S(0.019)LS(0.98)DS(0.001)ESDDSKSK;SLS(0.998)DS(0.002)ESDDSKSK;SLS(0.996)DS(0.004)ES(0.001)DDSKSK;S(0.003)LS(0.952)DS(0.045)ESDDSKSK 215.09 1.2523e-35 55553800.0 211513.7 125649.0 136843.6 289856.0 260785.0 293787.0 252160.0 306834.0 263593.8 224037.0 True False 247318.79182399999 138122.60233468807 140106.47040624294 273616.30804583075 209686.05131078602 278380.29253754445 228273.57931969408 298779.9326174962 267448.3606545234 264653.1346240833 0.9345016531744269 0.5219004964021272 0.5293966028600113 1.0338676261457431 0.792305186970964 1.0518684879095024 0.8625387326091444 1.1289491546808506 1.010561847432529 1.0 18.013743216185297 -5.768132174715235 24.996035851898288 0.9781639735465879 0.6479296615569993 0.5279072020774345 0.13884077286297047 113.53919098093942 424044.07436687936 0.03844741156546813 0.05852887052669017 1.7055632328730517e-06 5.768132174715235 -0.33023431198958864 SLS(ph)DSESDDSKSK ddPTM_PC-9_Lapatinib_30min_R1 3 SLSDSESDDSKSK 13 1 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 SLS(0.999)DSESDDSKSK;S(0.001)LS(0.874)DS(0.074)ES(0.051)DDSKSK;S(0.032)LS(0.457)DS(0.457)ES(0.053)DDSKSK 137.84 0.00029648 91618000.0 188306.2 127561.7 145502.6 141718.8 124636.3 108608.9 101524.9 111481.8 117774.2 104918.1 True False 185620.91905687234 127266.33872101732 133539.93788427822 152141.27331205798 117305.43787839377 103963.95052671168 106781.36255684916 116661.65141232009 104509.22937869273 123053.05379041933 1.5084625154692781 1.0342395804152407 1.0852224611322516 1.236387628145994 0.9532915621759802 0.8448709505721028 0.867766863703491 0.9480597824984912 0.849302200632014 1.0 16.908920935838132 -1.522878745281074 0.45654035573202656 0.9018912814691404 13.349212220430068 0.6880074141822684 0.10906375845550452 55.484567924613366 0.6584874884081172 0.07029522361173773 646.4451033972903 0.029999999999949133 1.522878745281074 12.447320938960928 SLS(ph)ELCLAVPAPGIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSELCLAVPAPGIR 15 0 A0A5F9ZHW8;O94827-5;O94827-3;O94827;O94827-7;O94827-2;O94827-6 A0A5F9ZHW8 PLEKHG5 Pleckstrin homology domain-containing family G member 5 1 S(0.001)LS(0.999)ELCLAVPAPGIR;S(0.001)LS(0.999)ELCLAVPAPGIR 121.18 6.9804e-05 5638100.0 16818.9 15607.8 20287.7 22842.4 23382.4 22078.4 23105.0 21911.9 21621.3 17209.199999999997 True False 19666.007581583028 17157.23923564328 20771.43570953071 21562.61438406 18800.78657196285 20920.569837198116 20916.327134285915 21336.735842577127 21937.470609019092 20329.091732047757 0.9673824999559911 0.8439747068776212 1.0217591608771002 1.0606777060318766 0.9248217687130796 1.0290951564854187 1.0288864554294088 1.0495666074909227 1.079117104599209 1.0 14.311258139102867 -5.284089878562595 23.211617581429042 1.0241007247547842 0.9056786323082573 0.4931209010677059 0.048081617230949676 223.4187322560012 228953.41488767383 0.012508683701161316 0.02608182324125533 5.198883929169036e-06 5.284089878562595 -0.1184220924465269 SLS(ph)ELESLK ddPTM_PC-9_AZD4547_30min_R2 2 SLSELESLK 9 0 P22059 P22059 OSBP Oxysterol-binding protein 1 1 S(0.033)LS(0.967)ELESLK;S(0.002)LS(0.998)ELESLK 104.43 0.0039533 0.0 12724.1 13237.5 14378.3 16891.7 15585.4 15282.4 13309.5 14854.8 13144.7 12778.6 True False 16770.09912227861 17516.26300157864 14187.63434738568 12997.579539163473 13421.636233586578 14326.789112112712 14494.019716082059 12559.331989345214 13839.502006563096 12331.225103503122 1.3599702366567348 1.4204803541054916 1.1505454022857127 1.0540379751457987 1.088426828715801 1.1618301500345396 1.1753917063734827 1.0184983149628246 1.1223136298624128 1.0 13.590028517728788 -5.33981058368177 4.26066170829914 1.096741734249966 1.3912353326727185 0.8181669174555912 0.05581465689668857 0.08205734175997968 2.762112319452776 0.014826726061513681 0.033646464298704486 4.572875908256673e-06 5.33981058368177 0.2944935984227526 SLS(ph)ELESLK ddPTM_PC-9_Lapatinib_30min_R1 2 SLSELESLK 9 0 P22059 P22059 OSBP Oxysterol-binding protein 1 1 S(0.007)LS(0.993)ELESLK;SLS(1)ELESLK 115.57 0.00063029 0.0 8721.7 12745.8 11335.7 12575.6 14253.4 12531.900000000001 13821.5 14555.5 14782.199999999999 10773.8 True False 8597.326958636106 12716.287883199619 10403.722503067407 13500.451574971814 13415.043035262579 11995.939850285731 14537.109640881112 15231.80166746519 13117.272972533126 12636.036974813878 0.6803815924068819 1.006350955489106 0.8233374533331996 1.0684086792307497 1.0616495553155958 0.9493435223556256 1.1504484887038908 1.2054255379139192 1.0380844087967174 1.0 13.62525644328079 -3.8575198071212085 0.5037811269635171 1.0957837261070251 1.216263437209096e-15 0.5690602848854602 0.09529071874692718 7.758634177506592 0.7451226551700452 0.054608137252387584 6.139826214882108 0.00013882899919354777 3.8575198071212085 -1.095783726107024 SLS(ph)EQPVMDTATATEQAK ddPTM_PC-9_AZD4547_30min_R2 5 SLSEQPVMDTATATEQAK 18 0 P18615;P18615-3;A0A0A0MT02;P18615-4;A2ABK4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 1 S(0.318)LS(0.594)EQPVMDT(0.085)AT(0.003)ATEQAK;S(0.405)LS(0.575)EQPVMDT(0.02)AT(0.001)ATEQAK;S(0.177)LS(0.793)EQPVMDT(0.028)AT(0.002)ATEQAK;S(0.149)LS(0.833)EQPVMDT(0.018)ATATEQAK;S(0.186)LS(0.669)EQPVMDT(0.145)ATATEQAK 161.95 2.5412e-06 51984500.0 131835.0 138382.0 154419.0 219497.0 176461.0 159627.0 175655.0 257593.0 196082.0 173790.0 True False 173755.7876616495 183111.27529249885 152371.30316441794 168895.35784484484 151962.4360885775 149645.4984556883 191287.95471117532 217787.92074827044 206446.49421066302 167705.66499755924 1.0360758395619987 1.0918610012080618 0.908563841100034 1.0070939335728635 0.9061258371372793 0.8923103370292602 1.1406171324860093 1.2986318664395748 1.2310048930885407 1.0 17.35557189754209 -7.42719353524348 5.283957014768646 1.2025675186963363 0.9754752331364819 0.5086584367105168 0.09263098315952908 0.16700777863441224 7.201122587267346 0.04006373644032577 0.026372946600517318 3.739439100006314e-08 7.42719353524348 -0.2270922855598544 SLS(ph)EQPVMDTATATEQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLSEQPVMDTATATEQAK 18 0 P18615;P18615-3;A0A0A0MT02;P18615-4;A2ABK4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 1 S(0.163)LS(0.818)EQPVMDT(0.018)ATATEQAK;S(0.235)LS(0.722)EQPVMDT(0.041)AT(0.002)ATEQAK;S(0.169)LS(0.723)EQPVMDT(0.042)AT(0.063)AT(0.003)EQAK 135.38 3.7454000000000004e-05 22975800.0 104839.0 103745.0 79547.0 99999.0 124955.0 125430.0 138720.0 194610.0 126467.0 104018.0 True False 122586.17203536372 114044.11797318094 81443.70216367753 94396.38023113206 100470.96474697275 118852.22999310463 125579.43735417181 189501.693706339 128316.34062294214 122875.63999396506 0.9976442201349628 0.9281263395965395 0.6628140628010367 0.7682269670031282 0.8176638164562748 0.9672562437838937 1.022004340000504 1.542223452228987 1.0442781061343347 1.0 16.906839405254672 -7.292032737942107 2.365940057637803 1.2207779513479895 0.8339974980153383 0.445852160450703 0.1659746222358431 0.2474969164341716 2.7184918214574236 0.07961491462453754 0.05117495769391338 5.1046651859025754e-08 7.292032737942107 -0.3867804533326512 SLS(ph)EQPVMDTATATEQAK ddPTM_PC-9_Lapatinib_30min_R1 4 SLSEQPVMDTATATEQAK 18 0 P18615;P18615-3;A0A0A0MT02;P18615-4;A2ABK4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 1 S(0.086)LS(0.717)EQPVMDT(0.19)AT(0.007)ATEQAK;S(0.056)LS(0.761)EQPVMDT(0.008)AT(0.174)AT(0.001)EQAK;S(0.151)LS(0.836)EQPVMDT(0.012)ATATEQAK;S(0.046)LS(0.935)EQPVMDT(0.019)ATATEQAK 145.99 7.5116e-05 50452000.0 228560.0 182378.0 201981.0 143623.0 282785.0 252121.0 316578.0 261668.0 267859.0 301066.0 True False 225300.69248722942 181955.71494627054 185374.9018492067 154185.51453228312 266152.142276701 241338.3725527562 332968.8598119498 273826.0505459987 237689.8987396838 353104.856954771 0.6380560562951647 0.5153022150855805 0.5249854206138866 0.4366564534455913 0.753748177161982 0.68347508622253 0.9429744543406254 0.7754808384894941 0.6731425355900141 1.0 18.42973713993073 -6.510996019944054 2.258345813897681 0.814159096240135 0.5287995962980231 0.6102557345873172 0.10744983238903676 0.21244066135012157 2.1720545614060605 0.03770772521761277 0.040886222579093065 3.0832162060004057e-07 6.510996019944054 -0.28535949994211196 SLS(ph)ESAATR ddPTM_PC-9_AZD4547_30min_R2 2 SLSESAATR 9 0 O14924-5;O14924-4;O14924;E9PBG5 O14924-5 RGS12 Regulator of G-protein signaling 12 1 SLS(0.987)ES(0.012)AATR;S(0.004)LS(0.991)ES(0.005)AATR 155.53 7.8345e-05 45632000.0 45215.0 37197.0 65192.0 67183.0 68657.0 61573.0 48825.0 50557.0 46617.0 47741.0 True False 59592.429469575625 49220.20282301948 64327.511484303875 51694.99731700299 59125.1606560854 57722.83057635684 53170.330413441974 42744.57733428427 49081.07944950831 46069.60212122943 1.2935303698252414 1.0683878426711702 1.3963114184279222 1.12210644192174 1.283387698910467 1.2529483199021914 1.1541304453536934 0.9278260580980154 1.065367990814298 1.0 15.491527517751875 -7.5869290837686165 4.623874101187312 0.9991379318166389 1.2310737166310688 0.5776742320367982 0.09091874550627879 0.1427063634864218 6.073221923158981 0.04159819544940445 0.023452344608432832 2.588635580648795e-08 7.5869290837686165 0.2319357848144299 SLS(ph)ESAATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSESAATR 9 0 O14924-5;O14924-4;O14924;E9PBG5 O14924-5 RGS12 Regulator of G-protein signaling 12 1 SLS(0.995)ES(0.005)AATR;S(0.049)LS(0.947)ES(0.004)AATR 120.63 0.0016654 19222400.0 17963.3 21709.0 28728.0 42967.0 63446.0 75429.0 80361.0 75554.0 75562.0 57801.0 True False 21004.131898652744 23864.12605021717 29412.98447154672 40559.69829089349 51014.21175092186 71473.37045483444 72748.62431674324 73570.78755608032 76666.9513007404 68279.86374753564 0.30761824564142937 0.34950459389395716 0.43077098953069154 0.5940213712327065 0.7471340590184331 1.0467708418269077 1.0654477077712226 1.0774887868568082 1.1228339819806314 1.0 16.059172559020098 -6.2937185939662585 1.0773876435148904 1.0917204002548724 0.3215063652094235 0.9795458829022176 0.04460784096792486 0.06139742021235598 0.14918324173508982 0.019319344092516327 0.02827561083717065 5.084888169324735e-07 6.2937185939662585 -0.7702140350454489 down SLS(ph)ESAATR ddPTM_PC-9_Lapatinib_30min_R1 2 SLSESAATR 9 0 O14924-5;O14924-4;O14924;E9PBG5 O14924-5 RGS12 Regulator of G-protein signaling 12 1 SLS(0.997)ES(0.002)AATR;S(0.001)LS(0.999)ESAATR 177.57 0.0013598 26664000.0 31287.0 31577.0 36671.0 31572.4 64487.0 91139.0 79127.0 82888.0 92782.0 69192.0 True False 30840.84164266691 31503.885396585094 33656.05193415356 33894.33961843889 60694.001446320064 87241.19742538568 83223.80888861557 86739.2790775208 82331.914122226 81151.74500745517 0.3800391678556469 0.3882095867894267 0.4147298610900071 0.4176661834606898 0.7479075334824197 1.0750378493693644 1.0255332017933816 1.0688529133853168 1.014542744763682 1.0 16.308334496954053 -6.46719996536487 2.3697049624606517 1.0425950113640905 0.39325196945281726 0.9897596834551299 0.030463260141959297 0.02649362022597233 0.2952085694670811 0.010739755465827963 0.011950934671109857 3.4103584985107135e-07 6.46719996536487 -0.6493430419112732 down SLS(ph)ESSVIMDR ddPTM_PC-9_AZD4547_30min_R2 7 SLSESSVIMDR 11 0 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2;H3BNX5 H3BSS6 ZNF106 Zinc finger protein 106 1 S(0.002)LS(0.996)ES(0.001)S(0.001)VIMDR;SLS(1)ESSVIMDR;S(0.008)LS(0.98)ES(0.011)S(0.001)VIMDR;S(0.083)LS(0.916)ES(0.001)S(0.001)VIMDR;S(0.011)LS(0.988)ES(0.001)S(0.001)VIMDR;SLS(0.999)ESSVIMDR;S(0.001)LS(0.999)ESSVIMDR 180.24 0.0010863 104036700.0 242152.0 229269.0 313691.0 388307.0 351515.0 307134.0 259826.0 354941.0 265919.0 290185.0 True False 319151.2989255038 303375.7206503444 309531.2523779418 298788.8204333456 302713.20984056825 287928.8624273427 282950.0106503429 300093.024182768 279974.9354556018 280025.7114754395 1.1397214107372993 1.0833852329197737 1.105367256267431 1.0670049505777324 1.0810193401369812 1.0282229474938638 1.0104429666815073 1.071662393433785 0.9998186737226015 1.0 18.095199773446744 -1.998161986274977 0.18524916305053396 0.9906120463824793 1.5276391410506975 0.7561485628300944 0.022225482566407422 22.993655651932364 0.30819200845856326 0.047677630943959166 3.3796283341428675 0.01004241151337859 1.998161986274977 0.5370270946682182 SLS(ph)ESSVIMDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SLSESSVIMDR 11 0 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2;H3BNX5 H3BSS6 ZNF106 Zinc finger protein 106 1 S(0.005)LS(0.992)ES(0.001)S(0.002)VIMDR;S(0.01)LS(0.986)ES(0.002)S(0.002)VIMDR;S(0.287)LS(0.712)ES(0.001)S(0.001)VIMDR;S(0.001)LS(0.998)ESSVIMDR;SLS(0.991)ES(0.004)S(0.004)VIMDR 123.95 0.00047214 88253200.0 184580.0 195098.0 228852.0 258307.0 286279.0 293270.0 289107.0 295685.0 270487.0 211704.0 True False 215825.74837882322 214466.04008223675 234308.69960604364 243834.89623259316 230184.68502099643 277890.4049276707 261720.69200657896 287923.5820541539 274442.36066387023 250084.25935205747 0.863012126145026 0.8575751254313092 0.9369190216653912 0.975010969760129 0.9204285212407258 1.1111871080877145 1.0465300482512185 1.1513062949268946 1.0973995779459373 1.0 17.932054729599123 -6.317648855284963 0.859826940079996 1.0963334312359776 0.8645901597222305 0.7151215996793966 0.05249370476260152 0.31393665072227633 0.5023661099718209 0.027154774584592447 0.042050435980813455 4.812282837922701e-07 6.317648855284963 -0.23174327151374707 SLS(ph)ESSVIMDR ddPTM_PC-9_Lapatinib_30min_R1 11 SLSESSVIMDR 11 0 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2;H3BNX5 H3BSS6 ZNF106 Zinc finger protein 106 1 S(0.153)LS(0.846)ESSVIMDR;S(0.044)LS(0.939)ES(0.008)S(0.008)VIMDR;S(0.004)LS(0.996)ESSVIMDR;S(0.001)LS(0.993)ES(0.003)S(0.003)VIMDR;S(0.028)LS(0.97)ES(0.001)S(0.001)VIMDR;SLS(0.996)ES(0.002)S(0.002)VIMDR;S(0.001)LS(0.992)ES(0.003)S(0.003)VIMDR;S(0.017)LS(0.982)ESSVIMDR;S(0.003)LS(0.996)ESSVIMDR;SLS(0.974)ES(0.013)S(0.013)VIMDR;S(0.002)LS(0.995)ES(0.002)S(0.002)VIMDR 165.58 0.00035618 90451400.0 344419.0 345219.0 398948.0 357869.0 430923.0 440174.0 369622.0 376865.0 454715.0 359875.0 True False 339507.5219012913 344419.66661569243 366148.03542381426 384187.88007598725 405576.95636721456 421348.7841157108 388759.2185856643 394375.52371332364 403500.2083387727 422078.91424670536 0.8043697764604487 0.8160077535035994 0.8674871524375665 0.9102276069906425 0.9609031455434294 0.9982701572944064 0.9210581373852623 0.9343644290243102 0.9559828617805025 1.0 18.687153232963517 -5.669966088638595 1.483089936967266 0.9584060289209133 0.8041188249357885 0.8671470447720452 0.023801277850462932 0.15268060114484183 0.6639458780551574 0.008049767369697198 0.02096469126222368 2.138129036214123e-06 5.669966088638595 -0.15428720398512485 SLS(ph)FEMQQDELIEKPMSPMQYAR ddPTM_PC-9_AZD4547_30min_R2 1 SLSFEMQQDELIEKPMSPMQYAR 23 1 Q9Y6Y0 Q9Y6Y0 IVNS1ABP Influenza virus NS1A-binding protein 1 S(0.031)LS(0.969)FEMQQDELIEKPMSPMQYAR 54.56 0.004978 5704500.0 13145.0 11649.0 14045.0 25195.0 22369.0 15548.0 14682.0 16665.0 14415.0 15276.0 True False 17324.836567014732 15414.311441389189 13858.754123160028 19386.68200886966 19263.45046704596 14575.781102125868 15988.669557197249 14089.807173603002 15176.947471194246 14741.191889652519 1.1752670134614953 1.04566249166115 0.9401379635311639 1.3151366696798792 1.3067769968158283 0.9887790085927339 1.0846252919630188 0.9558119369908784 1.029560403582264 1.0 13.847565556884279 -6.853604662253098 24.64441878348047 1.013545351816514 1.1473418395294137 0.30757568131038193 0.10819754940940246 24.40821055137447 6515.6397658370415 0.041705301987988 0.03678062880332704 1.4008619452923994e-07 6.853604662253098 0.13379648771289965 SLS(ph)FSEPQQPAPAMK ddPTM_PC-9_AZD4547_30min_R2 4 SLSFSEPQQPAPAMK 15 0 Q9H8N7 Q9H8N7 ZNF395 Zinc finger protein 395 1 S(0.006)LS(0.981)FS(0.013)EPQQPAPAMK;S(0.034)LS(0.961)FS(0.005)EPQQPAPAMK;S(0.008)LS(0.928)FS(0.064)EPQQPAPAMK;SLS(0.853)FS(0.146)EPQQPAPAMK 141.82 6.8891e-06 70144000.0 185977.0 162591.0 239724.0 328974.0 271252.0 271981.0 202857.0 256099.0 204492.0 235843.0 True False 245113.81743809028 215145.36110970133 236545.10312712076 253134.12689763375 233593.34195033976 254973.9850744333 220910.88001391955 216524.7841195658 215301.02964130792 227586.20835502178 1.077015251538118 0.9453356715451166 1.0393648404130167 1.1122560049981527 1.0263949807799742 1.1203402302686467 0.9706690120225163 0.9513967726102244 0.9460196696341561 1.0 17.7960536079131 -7.4195708834472045 9.070624847066773 0.961438190324541 1.0492830392172234 0.4356208506426872 0.047998579184593826 0.35082516158418914 28.2367818203375 0.02061885573436659 0.013870324683738396 3.8056523851228386e-08 7.4195708834472045 0.0878448488926824 SLS(ph)FSEPQQPAPAMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLSFSEPQQPAPAMK 15 0 Q9H8N7 Q9H8N7 ZNF395 Zinc finger protein 395 1 S(0.002)LS(0.982)FS(0.017)EPQQPAPAMK;SLS(0.987)FS(0.013)EPQQPAPAMK;S(0.005)LS(0.843)FS(0.153)EPQQPAPAMK 160.79 2.3658000000000003e-05 52259600.0 125917.0 124458.0 129500.0 120952.0 181535.0 160261.0 167496.0 154784.0 148619.0 126670.0 True False 147232.2611258875 136813.36772573265 132587.77113148497 114175.45157167494 145964.51990990117 151856.63103663342 151629.56631397366 150721.08400720425 150792.2717154756 149634.2682808319 0.9839474795276418 0.9143184198218745 0.8860789219929606 0.7630301058938702 0.9754752142467568 1.0148519639340277 1.0133344992164295 1.0072631472647204 1.0077388919526802 1.0 17.19108108427011 -6.505047992106744 24.70826482929259 1.0078050330554273 0.8863142059798748 0.5652246593883399 0.05065270730760117 497.6687446002211 689625.9443478663 0.016621750187652634 0.01846185683925919 3.1257339359665485e-07 6.505047992106744 -0.12149082707555259 SLS(ph)FSEPQQPAPAMK ddPTM_PC-9_Lapatinib_30min_R1 6 SLSFSEPQQPAPAMK 15 0 Q9H8N7 Q9H8N7 ZNF395 Zinc finger protein 395 1 S(0.001)LS(0.998)FS(0.001)EPQQPAPAMK;S(0.021)LS(0.975)FS(0.004)EPQQPAPAMK;S(0.007)LS(0.851)FS(0.142)EPQQPAPAMK;SLS(0.997)FS(0.003)EPQQPAPAMK;S(0.012)LS(0.987)FS(0.001)EPQQPAPAMK;S(0.007)LS(0.76)FS(0.232)EPQQPAPAMK 172.1 2.1816999999999998e-05 70848400.0 264851.0 228067.0 267437.0 236061.0 303197.0 303712.0 283066.0 273706.0 329894.0 244010.0 True False 261074.1761722748 227538.92487389475 245449.3621966737 253421.71341641116 285363.54856823717 290722.9457472513 297721.772427425 286423.37997287884 292737.86378217355 286186.80337711284 0.9122509252400897 0.7950713386810612 0.8576543687559248 0.8855115275265624 0.997123365580939 1.0158502849069566 1.0403057335774926 1.0008266509600523 1.0228908542523825 1.0 18.126597622597323 -6.216906822527218 2.4514409047419754 1.0177356195489269 0.8495550170311386 0.871586945484647 0.028476183020152396 0.09106075689980517 1.0769706710255968 0.008941188038528135 0.011720119082607942 6.068665182630136e-07 6.216906822527218 -0.16818060251778832 SLS(ph)FSGPR ddPTM_PC-9_AZD4547_30min_R2 1 SLSFSGPR 8 0 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 S(0.075)LS(0.917)FS(0.007)GPR 101.46 0.011576000000000001 0.0 12080.0 15995.0 21514.0 23919.0 21690.0 15623.0 16220.0 26573.0 19757.0 18033.0 True False 15921.188720390883 21165.07095072711 21228.71030300211 18404.84409486619 18678.717896652826 14646.091340269646 17663.54857769644 22466.753436792835 20801.3146852851 17401.670158818004 0.9149230260707526 1.2162666432337856 1.2199237262433007 1.0576481410630487 1.0733865040642492 0.8416486007722647 1.0150490393444065 1.2910688015430625 1.1953631171858743 1.0 14.08693815770454 -10.80171116069818 3.8245391066784045 0.9998373216531057 1.0938477722129534 0.03936884757070147 0.13551377414459453 17401306.970115498 24792141.05032868 18356.46481043552 0.035005749269664085 1.57866085176901e-11 10.80171116069818 0.09401045055984769 SLS(ph)FSGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSFSGPR 8 0 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 S(0.155)LS(0.72)FS(0.125)GPR 74.165 0.028172000000000003 1670600.0 19651.0 25907.0 24643.0 21036.0 29832.0 21610.0 22169.0 25427.0 17277.0 14156.0 True False 22977.52617505832 28478.875746601698 25230.58257909793 19857.42111963218 23986.63375080383 20476.733557769196 20068.991830339077 24759.568192133458 17529.64344012722 16722.370741165665 1.374059128978301 1.703040566879366 1.5087922023512788 1.1874764306444257 1.434403896557301 1.2245113970210797 1.2001283873544912 1.4806254792080722 1.0482750150356541 1.0 14.029491773264029 -1.522878745280339 0.08214307328606452 0.707418773504147 3.013539981585754 0.49506171790296893 0.14927607568983448 155.59245664586794 0.9326863605200852 3.834349838326552 40.640513078023 0.029999999999999905 1.522878745280339 2.306121208081607 SLS(ph)FSGPR ddPTM_PC-9_Lapatinib_30min_R1 2 SLSFSGPR 8 0 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 S(0.45)LS(0.548)FS(0.002)GPR;S(0.035)LS(0.958)FS(0.007)GPR 89.029 0.010532 4517400.0 37869.0 28081.0 33041.0 31933.0 26305.0 24999.0 25094.0 20851.5 33346.0 38845.0 True False 37328.98111567591 28015.980169791485 30324.496521948342 34281.459345365234 24757.791617619816 23929.851045515294 26393.244534114987 21820.336812143218 29590.222331052864 45559.306492291034 0.8193491953612648 0.6149342983201904 0.6656048754183619 0.7524578836854311 0.5434189746020172 0.5252461656668194 0.5793162048807946 0.47894356811237626 0.649487988498239 1.0 15.475458165933764 -10.850652380426633 8.72542133267807 1.000000519366994 0.6190058657153669 0.5654542854363386 0.09836720584521944 1.037643038057148e-06 8.000114443058855e-08 0.09945829206956446 0.0241221463249834 1.4104172780731763e-11 10.850652380426633 -0.3809946536516272 SLS(ph)GSPLK ddPTM_PC-9_AZD4547_30min_R2 2 SLSGSPLK 8 0 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 S(0.043)LS(0.887)GS(0.07)PLK;SLS(0.649)GS(0.351)PLK 123.86 0.0032984999999999998 115996000.0 429720.0 428270.0 495390.0 568870.0 605510.0 463860.0 433050.0 520860.0 460220.0 567150.0 True False 566362.0212687395 566699.9022236888 488820.80491792376 437725.8104538875 521445.38836340356 434854.7608716306 471590.61107099015 440373.05517208966 484546.2896422481 547294.2511270258 1.0348400702226417 1.0354574363913043 0.8931590344888705 0.7997997595488945 0.9527697162716536 0.7945538619785388 0.8616765297641231 0.804636727437285 0.8853487655761726 1.0 19.061957176744883 -5.3078462684759655 4.055854065521974 0.8620536194783042 1.0379415490112065 0.5090141635758089 0.06302871707296188 0.14388020616429312 5.077359304804967 0.015574962624994328 0.03719407218091092 4.9221373862509875e-06 5.3078462684759655 0.17588792953290233 SLS(ph)GSPLK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSGSPLK 8 0 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 S(0.106)LS(0.555)GS(0.338)PLK 106.2 0.0038299 72910000.0 447590.0 555630.0 512600.0 432930.0 418590.0 416550.0 488870.0 432520.0 424970.0 377790.0 True False 441207.28452204744 554343.4728728057 470456.00669322227 464769.11641214247 393969.35917960387 398735.12752547686 514181.2965407187 452616.45819189 377105.4034675082 443090.4981264685 0.9957498217353251 1.2510840905339904 1.0617605403015051 1.0489259381037017 0.8891397149012112 0.8998954597570008 1.160443066856196 1.021498903961381 0.851079869828022 1.0 18.7572418636556 -5.799626617823923 2.651100347978802 0.9779608885234627 1.1251491954021244 0.25401988220687544 0.10099653868322926 0.3705695539776045 5.306997152865471 0.0303694520277512 0.05302667910071303 1.5862563811555002e-06 5.799626617823923 0.1471883068786617 SLS(ph)GSSPCPK ddPTM_PC-9_AZD4547_30min_R2 2 SLSGSSPCPK 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.034)LS(0.966)GSSPCPK;SLS(0.786)GS(0.211)S(0.002)PCPK 124.1 0.00042386 8161400.0 41087.0 36251.0 51287.0 66786.0 54636.0 50492.0 44726.0 60325.0 42408.0 52281.0 True False 54151.81133730957 47968.42682305777 50606.9008696695 51389.51953341412 47050.73448600845 47334.727258074294 48706.527354257174 51003.157380594144 44649.60030235207 50450.658103097914 1.0733618425085398 0.9507988324955523 1.0030969420904738 1.0186094981833063 0.9326089342552958 0.9382380535323029 0.9654289792359787 1.0109512798894946 0.8850152204379346 1.0 15.622585468224655 -6.253863960158698 24.86831737322991 0.9555672854961333 1.0065355103074598 0.2852878345691433 0.043213227086824665 795.0497110748962 2609960.119695375 0.012391290960875528 0.015691352579131165 5.573603109793332e-07 6.253863960158698 0.05096822481132646 SLS(ph)GSSPCPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSGSSPCPK 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.093)LS(0.906)GS(0.001)S(0.001)PCPK 73.499 0.027795 10029000.0 30803.0 38057.0 43852.0 43193.0 41950.0 41471.0 44634.0 35317.0 33793.0 30302.0 True False 36017.33951301821 41835.04745004906 44897.59798963609 40773.03624359541 33730.198640594695 39296.18775447694 40405.94439782376 34389.96617145462 34287.15869492498 35795.51272949998 1.006197055625227 1.1687232354007253 1.2542800637867342 1.1390543991284507 0.9423024303489526 1.0977964766542363 1.1287991515351088 0.9607340012513073 0.9578619240357488 1.0 15.127491124339231 -7.1374220804586725 0.6610177558850167 0.9729230827818937 1.1413116693698657 0.2932195089959091 0.0850313781803395 0.9959499105990547 0.8920406071366231 0.07797177669896994 0.0586325078167476 7.287489122722545e-08 7.1374220804586725 0.16838858658797207 SLS(ph)GSSPCPK ddPTM_PC-9_Lapatinib_30min_R1 2 SLSGSSPCPK 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SLS(0.989)GS(0.01)SPCPK;S(0.012)LS(0.815)GS(0.169)S(0.005)PCPK 107.06 0.0022272 12933900.0 43256.0 35853.0 39788.0 37616.0 48927.0 46189.0 40259.0 34206.0 42883.0 35262.0 True False 42639.161507821096 35769.98458130177 36516.78422612151 40382.40612329751 46049.21005418303 44213.60414181791 42343.41403120012 35795.33563514234 38053.06496199064 41356.98971633846 1.0310025415359498 0.8649078384728399 0.882965236991009 0.9764348517693024 1.113456525004064 1.069072107159456 1.0238514534454126 0.8655208195919798 0.920112059001176 1.0 15.335843558447893 -4.450142349578686 22.354809208781163 0.9698874614029735 3.614219577634206 0.050178161346777994 0.08139876943217549 1710.0014439880188 569146.7157270194 0.022196866324020934 18860.28568919134 3.546971103905337e-05 4.450142349578686 2.6443321162312325 SLS(ph)IEIGHEVK ddPTM_PC-9_AZD4547_30min_R2 3 SLSIEIGHEVK 11 0 A0A3B3IU16;C9JTT8;Q68DU7;H7C1N3;O15155-2;O15155 A0A3B3IU16 BET1;DKFZp781C0425 BET1 homolog 1 S(0.307)LS(0.693)IEIGHEVK;S(0.001)LS(0.999)IEIGHEVK;S(0.003)LS(0.997)IEIGHEVK 115.34 0.0013689 14238800.0 65148.0 82817.0 125980.0 156578.0 125750.0 116755.0 110142.0 121593.0 109263.0 77641.0 True False 85863.70883741933 109585.97567529645 124309.42288613041 120481.36120598513 108291.78310300098 109454.29139302204 119944.42462667359 102803.59577917233 115038.41911516448 74922.81222208102 1.146028910165679 1.4626516600907782 1.6591665368574395 1.6080731306356015 1.445377981568684 1.4608940607913274 1.6009066006644628 1.372126762600008 1.5354258029473793 1.0 16.193117431595788 -10.760431971919232 12.692912062868677 1.000001311233555 1.4847397343216029 0.5154968040987784 0.13846017659568136 5.640566584497877e-10 0.0 0.135772267257537 0.03292961170190679 1.736073180849266e-11 10.760431971919232 0.4847384230880478 SLS(ph)IEIGHEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSIEIGHEVK 11 0 A0A3B3IU16;C9JTT8;Q68DU7;H7C1N3;O15155-2;O15155 A0A3B3IU16 BET1;DKFZp781C0425 BET1 homolog 1 S(0.238)LS(0.762)IEIGHEVK;S(0.182)LS(0.818)IEIGHEVK 66.24600000000001 0.024187 10184100.0 139872.0 135507.0 126820.0 151494.0 193228.0 130401.0 149972.0 104015.0 111889.0 119462.0 True False 163549.56700207398 148959.23942543584 129843.86976752832 143006.28233017476 155366.36049880448 123562.54200215913 135765.5664567467 101284.7164630024 113525.16495180836 141119.51493932848 1.1589436590140552 1.0555537941685662 0.9200986116154956 1.0133699962875968 1.1009558852693133 0.8755879160673304 0.9620608922523323 0.7177229634508576 0.8044611335336309 1.0 17.10655798157422 -7.06414052424845 1.7105968777197595 0.8357533924279179 1.0404123858268177 0.42723932907018813 0.09710507192618932 0.34179120885478836 1.9965219803510093 0.047653558703272654 0.03432522605834106 8.626993597977277e-08 7.06414052424845 0.2046589933988998 SLS(ph)IEIGHEVK ddPTM_PC-9_Lapatinib_30min_R1 2 SLSIEIGHEVK 11 0 A0A3B3IU16;C9JTT8;Q68DU7;H7C1N3;O15155-2;O15155 A0A3B3IU16 BET1;DKFZp781C0425 BET1 homolog 1 S(0.085)LS(0.915)IEIGHEVK;S(0.225)LS(0.775)IEIGHEVK 87.083 0.0059882 9807000.0 189318.0 200275.0 146231.0 86353.0 116390.0 167632.0 167385.0 159782.0 172359.0 93058.0 True False 186618.29060333036 199811.2755423595 134208.4516479838 92703.68768516363 109544.16903154431 160462.77012927804 176051.37627890497 167206.055032869 152946.11439926657 109142.95130800942 1.7098519727277655 1.8307300026959819 1.229657527486477 0.849378604611369 1.0036760754471685 1.4702073583885442 1.6130347784171153 1.5319913290689862 1.4013375354643052 1.0 16.73585943535329 SLS(ph)KSDSDLLTCSPTEDATMGSR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSKSDSDLLTCSPTEDATMGSR 23 1 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 S(0.061)LS(0.713)KS(0.196)DS(0.029)DLLT(0.001)CSPTEDATMGSR 67.138 0.002306 51319000.0 55086.0 50175.0 55119.0 53884.0 65761.0 60501.0 64965.0 66249.0 75410.0 62091.0 True False 54300.46353846481 50058.822870242824 50587.32858549291 57846.809111754614 61893.067271100415 57913.51326471935 68328.56982381381 69327.17039386509 66916.53169749588 72823.346618943 0.7456463628703934 0.6874007470733484 0.6946581135607135 0.7943442837699435 0.8499069343100009 0.7952602558594133 0.9382783543490708 0.9519909975660404 0.9188884444935599 1.0 16.152113421342747 -6.770183834473608 0.5655194942554738 0.9851240075684484 0.6863967442036876 0.8774677064235616 0.03695695294799508 0.29642938234337346 0.20532274935072028 0.032082303957539304 0.03786599322281904 1.697524947355264e-07 6.770183834473608 -0.29872726336476085 SLS(ph)LDPGQSLEPHPEGPQR ddPTM_PC-9_AZD4547_30min_R2 3 SLSLDPGQSLEPHPEGPQR 19 0 P98174 P98174 FGD1 FYVE, RhoGEF and PH domain-containing protein 1 1 S(0.028)LS(0.972)LDPGQSLEPHPEGPQR;S(0.024)LS(0.929)LDPGQS(0.047)LEPHPEGPQR;S(0.009)LS(0.941)LDPGQS(0.05)LEPHPEGPQR 171.84 1.6962e-08 14393200.0 41147.6 33481.7 66346.0 120069.0 87759.0 78657.0 56634.6 89990.0 55102.9 69066.0 True False 54231.68087675131 44304.00475467082 65466.20869029374 92388.9470975578 75575.17768060659 73738.56535566735 61674.96968424213 76084.11326447842 58015.52679920008 66648.0203620542 0.813702801405755 0.6647459971653583 0.9822678653418291 1.3862219252075354 1.1339448234179665 1.1063879310307336 0.9253833699666276 1.1415809929711975 0.8704763695011563 1.0 16.02427440330687 -5.418182173002401 5.041080150641048 1.089971086765669 0.7455872492360136 0.4875241053468812 0.13736046762043258 0.1780244867497644 6.841652804725273 0.03722863192036441 0.07954106181959762 3.81784090717571e-06 5.418182173002401 -0.3443838375296553 SLS(ph)LDPGQSLEPHPEGPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSLDPGQSLEPHPEGPQR 19 0 P98174 P98174 FGD1 FYVE, RhoGEF and PH domain-containing protein 1 1 S(0.228)LS(0.733)LDPGQS(0.039)LEPHPEGPQR;S(0.036)LS(0.964)LDPGQSLEPHPEGPQR 109.89 0.0017550999999999999 7405500.0 23143.1 27431.7 43944.7 39337.2 54775.0 42296.5 42745.4 37534.5 36768.9 31089.2 True False 27060.76973293938 30154.93788621047 44992.5083092028 37133.26421692311 44042.23195562753 40078.39708126723 38696.24626210368 36549.25914609008 37306.57560257531 36725.42585802822 0.736840189070915 0.8210915784280435 1.2251051487635067 1.0111050682018365 1.199229986491766 1.0912983619632022 1.0536636501287742 0.9952031403905524 1.0158241798691097 1.0 15.164491599526466 -5.1103637381247 5.589896625420445 1.0752322579104134 0.7565763473249179 0.7057761260541011 0.07690327350410026 0.10824281469849525 4.547022514963597 0.0196450394813942 0.05508950844940009 7.755972523647787e-06 5.1103637381247 -0.3186559105854956 SLS(ph)LDPGQSLEPHPEGPQR ddPTM_PC-9_Lapatinib_30min_R1 2 SLSLDPGQSLEPHPEGPQR 19 0 P98174 P98174 FGD1 FYVE, RhoGEF and PH domain-containing protein 1 1 S(0.162)LS(0.838)LDPGQSLEPHPEGPQR;S(0.272)LS(0.728)LDPGQSLEPHPEGPQR 130.49 2.1821e-05 8349500.0 80279.0 78738.0 151546.0 105140.0 127257.0 142876.0 100576.0 105895.0 148672.0 83868.0 True False 79134.20673863444 78555.68699864813 139086.47286447696 112872.34633675817 119771.9934568883 136765.52654022322 105783.33315785241 110815.26828870371 131926.9937744345 98364.47205291443 0.8044998878870085 0.7986184987237027 1.4139909457314674 1.1474909993522797 1.217634690220854 1.3903955735832267 1.0754221615803221 1.1265781839309976 1.3412057323244246 1.0 16.58584970681668 -5.243856579955607 24.857289968035683 1.217702727313469 0.8015590723218808 0.6233079106987399 0.1282551375846844 460.3553095776494 650814.3269813653 0.03126799050262692 0.08230998128496071 5.703525926310234e-06 5.243856579955607 -0.41614365499158823 SLS(ph)LESTDR ddPTM_PC-9_AZD4547_30min_R2 1 SLSLESTDR 9 0 H0Y7V8;A0A0A0MRJ1;H0Y5V1;A0A0A0MRJ0;Q5VT25-3;Q5VT25-4;Q5VT25-5;Q5VT25;Q5VT25-2;Q5VT25-6 H0Y7V8 CDC42BPA Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase MRCK alpha 1 S(0.005)LS(0.99)LES(0.001)T(0.004)DR 83.397 0.014378 2914300.0 10989.0 13759.0 12986.0 15525.0 18122.0 14084.0 12144.0 21525.0 11685.0 18046.0 True False 14483.273414600606 18206.327678090303 12813.79715509833 11945.951108858955 15606.073108489742 13203.325253559353 13224.792473954727 18198.805845292816 12302.645244599695 17414.21503277491 0.8316925791568529 1.0454865547384464 0.7358239881029242 0.6859884919518763 0.8961686231115151 0.7581923864331332 0.7594251276365105 1.0450546183701788 0.7064714212753866 1.0 14.08797782268102 -10.820503613218966 6.190524381691144 1.000007496717953 0.8329132694907042 0.14635630683508027 0.12336067465178135 1.2627699881198028e-05 1.4328267895139302e-06 0.11817063874552643 0.028659304142466195 1.5118071214600723e-11 10.820503613218966 -0.16709422722724887 SLS(ph)LESTDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSLESTDR 9 0 H0Y7V8;A0A0A0MRJ1;H0Y5V1;A0A0A0MRJ0;Q5VT25-3;Q5VT25-4;Q5VT25-5;Q5VT25;Q5VT25-2;Q5VT25-6 H0Y7V8 CDC42BPA Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase MRCK alpha 1 S(0.003)LS(0.91)LES(0.073)T(0.015)DR 76.143 0.024945 2299700.0 9241.8 14340.0 18616.0 18413.0 19780.0 16958.0 12728.0 13754.0 12560.0 12525.0 True False 10806.254206129654 15763.580430241582 19059.876041573156 17381.37930575144 15904.250991918081 16068.69262714715 11522.311697259946 13392.97207356761 12743.666238814489 14795.683352154556 0.7303653335184441 1.0654175312521865 1.2882051871431572 1.1747601575442175 1.074925071953645 1.0860392348696228 0.7787617119814922 0.9051945594400219 0.8613097438962661 1.0 13.852888709808731 -7.2421559261562525 23.348773533179696 0.8784160657429555 1.0846566547335819 0.2828652566849452 0.14186723217555106 432.67543927920485 523891.8756105706 0.05668974361633605 0.043819927712709206 5.7259041508293076e-08 7.2421559261562525 0.20624058899062636 SLS(ph)LESTDR ddPTM_PC-9_Lapatinib_30min_R1 2 SLSLESTDR 9 0 H0Y7V8;A0A0A0MRJ1;H0Y5V1;A0A0A0MRJ0;Q5VT25-3;Q5VT25-4;Q5VT25-5;Q5VT25;Q5VT25-2;Q5VT25-6 H0Y7V8 CDC42BPA Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase MRCK alpha 1 S(0.006)LS(0.989)LES(0.005)T(0.001)DR;S(0.003)LS(0.996)LESTDR 102.52 0.0031496 7481300.0 23246.0 25486.0 36301.0 28595.0 30839.0 28173.0 25613.0 25317.0 32420.0 26742.0 True False 22914.507777205705 25426.988732855163 33316.47190591228 30697.97169012367 29025.110651806797 26968.10646447066 26939.115814628494 26493.320244252427 28768.518202265168 31364.319068524826 0.7305915912646483 0.8106979359986176 1.0622411994063186 0.9787546040153042 0.9254181666878429 0.8598339535301464 0.8589096340899944 0.8446961716710562 0.9172371362315137 1.0 14.936836621071803 -5.014846018895334 18.222623328627144 0.9227277551992733 0.7506148122456305 0.5013252444801538 0.0656731560526044 15.536618779284682 19079.69036966711 0.018204116969732613 0.05314831286683054 9.663934574969328e-06 5.014846018895334 -0.17211294295364277 SLS(ph)LGDK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSLGDK 7 0 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 S(0.003)LS(0.997)LGDK 81.525 0.023815 10919000.0 48414.0 85569.0 71694.0 68946.0 90227.0 75884.0 94768.0 89263.0 73968.0 74754.0 True False 47723.60748195978 85370.87023784358 65799.5960668433 74016.51883711379 84920.0252531072 72638.61821424389 99674.62333661469 93410.48485060244 65636.94492242899 87675.12929655614 0.544323206191546 0.9737182131671739 0.7504932880598316 0.8442133981548761 0.9685759910985707 0.8284974176490564 1.1368631462118628 1.0654159919701605 0.7486381308936055 1.0 16.4198800326051 -3.8733969357982803 0.5184445696528301 0.9705756053658193 1.1718916341286456e-12 0.37634600206030133 0.13253563495319157 11.9603027059299 1.2062988434314013 0.07380420248888264 8.635587950551123 0.00013384528111844406 3.8733969357982803 -0.9705756053646475 SLS(ph)LGDKEISR ddPTM_PC-9_AZD4547_30min_R2 2 SLSLGDKEISR 11 1 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 S(0.001)LS(0.998)LGDKEISR;S(0.009)LS(0.991)LGDKEISR 62.732 0.025394999999999997 22761000.0 82337.0 82322.0 103351.0 141154.0 121072.0 118195.0 91969.0 103065.0 87375.0 105452.0 True False 108518.45328400879 108930.9766055492 101980.4982116563 108613.12610756054 104263.24265484307 110804.24796538254 100154.0628324391 87138.67244808849 91993.4641204021 101760.15757709062 1.0664139666037593 1.0704678451684408 1.0021652937634138 1.0673443191681216 1.0245978891675378 1.0888765367864173 0.9842168606761955 0.8563142444239504 0.9040224220438187 1.0 16.634813284207794 -7.52866881794326 5.394602806853939 0.9106723735612826 1.050378746021746 0.6841735499560702 0.04056888422075635 0.08677704682571283 8.288994791635364 0.01796617266814577 0.010737675550366768 2.9602690328055636e-08 7.52866881794326 0.13970637246046336 SLS(ph)LGDKEISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSLGDKEISR 11 1 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 S(0.051)LS(0.949)LGDKEISR 60.901 0.029069 37025000.0 72630.0 70760.0 79003.0 102890.0 109940.0 103300.0 95812.0 86443.0 78489.0 68587.0 True False 84924.8244921117 77784.5851634513 80886.73114054608 97125.40687388073 88398.04621089347 97882.76615074313 86735.99374119037 84173.96284392937 79636.75313840063 81021.28016560683 1.0481792477053689 0.9600512976894495 0.9983393372113384 1.198764160173194 1.0910472659801054 1.2081118189032753 1.0705334890278542 1.0389117855442236 0.9829115631797444 1.0 16.306013259858688 -5.609180629301759 24.999917265022937 1.09140665161431 0.9978472927134137 0.2078989080611493 0.07240544641527337 31.525222712654692 9126.152416291228 0.02030002172571466 0.03516067063209221 2.4593445147588435e-06 5.609180629301759 -0.09355935890089628 SLS(ph)LGDKEISR ddPTM_PC-9_Lapatinib_30min_R1 3 SLSLGDKEISR 11 1 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 S(0.017)LS(0.983)LGDKEISR;S(0.006)LS(0.992)LGDKEIS(0.002)R;S(0.003)LS(0.997)LGDKEISR 70.563 0.015056 102387000.0 349895.0 242666.0 276924.0 230551.0 266886.0 268553.0 242071.0 237299.0 289847.0 225610.0 True False 344905.43313711544 242104.12178635426 254156.37767755348 247506.48963559064 251188.29019806447 257067.61421761944 254604.2519175004 248324.77784259012 257201.37863577876 264606.38789357187 1.3034660118479109 0.9149594751421182 0.9605073396027706 0.93537609430329 0.9492903485727475 0.9715094796615997 0.9621999451498712 0.9384685676691584 0.9720150019175974 1.0 18.013488364742507 -4.757533509512917 24.999997655661197 0.9540728170408951 1.3034665142270232 0.9560832303268519 0.02233501265040993 19.464952528141136 124570.34626864658 0.0051868262819229965 0.03823645883557994 1.7476984074195206e-05 4.757533509512917 0.3493936971861281 SLS(ph)MDSQVPVYSPSIDLK ddPTM_PC-9_AZD4547_30min_R2 2 SLSMDSQVPVYSPSIDLK 18 0 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 S(0.133)LS(0.867)MDSQVPVYSPSIDLK;S(0.042)LS(0.957)MDSQVPVYSPSIDLK 132.79 3.5171e-05 4390200.0 24807.5 25207.0 33663.0 43764.0 41313.0 39293.0 31841.0 40419.0 37983.0 37574.0 True False 32695.7689719451 33354.66980024874 33216.606624986554 33674.885947059825 35577.40306428854 36836.00249844558 34674.78731580967 34173.1722862202 39990.70383616865 36258.545696635505 0.9017396683667597 0.919911958943896 0.916104217276116 0.9287434258617984 0.9812142870250262 1.0159260883390493 0.9563204108053127 0.9424860161832467 1.1029318211149175 1.0 15.14603344036433 -6.202817939866086 0.49583930677829297 1.0178467312160924 0.8849406492299244 0.5156263754996382 0.040225150682999124 1.220070264340605 0.5662492746385663 0.03372804989128644 0.08096141931382997 6.268766018798845e-07 6.202817939866086 -0.13290608198616793 SLS(ph)MDSQVPVYSPSIDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLSMDSQVPVYSPSIDLK 18 0 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 S(0.036)LS(0.962)MDS(0.001)QVPVYSPSIDLK;S(0.025)LS(0.975)MDSQVPVYSPSIDLK;S(0.034)LS(0.962)MDS(0.003)QVPVYSPSIDLK 142.94 3.8754e-05 11914600.0 87082.0 99909.0 82848.0 106359.0 112644.0 106754.0 109937.0 107694.0 94104.9 84856.0 True False 101823.26265210037 109827.30524442135 84823.41052278978 100400.05005053036 90572.21682172001 101155.63231032365 99522.97148504623 104867.14661122496 95481.00613352019 100239.7210802735 1.015797545671129 1.0956465566825546 0.8462055720891511 1.0015994554706358 0.903556153644805 1.009137208485613 0.992849644956082 1.046163591449399 0.9525266541499805 1.0 16.61309477987696 SLS(ph)MVDLQDAR ddPTM_PC-9_AZD4547_30min_R2 2 SLSMVDLQDAR 11 0 A0A3B3ITG3;Q5VWQ8-2;Q5VWQ8;H0Y3A3;Q5VWQ8-3;Q5VWQ8-4;Q5VWQ8-5 A0A3B3ITG3 DAB2IP Disabled homolog 2-interacting protein 1 S(0.021)LS(0.979)MVDLQDAR;SLS(1)MVDLQDAR 119.21 0.00086932 18235500.0 95236.0 112168.0 139853.0 211610.0 180298.0 161629.0 137612.0 179811.0 133404.0 149978.0 True False 125519.06696814141 148424.11243520855 137998.4578416732 162826.5838419094 155266.73487001905 151522.31307920677 149859.201410232 152025.34159572312 140455.4630903361 144727.31586975028 0.8672797268008781 1.025543184734976 0.9535066480875467 1.1250577188099573 1.0728225970123975 1.0469503436073655 1.0354589975613189 1.0504260421200708 0.9704834380867071 1.0 17.142977716628565 -3.9603056286652163 1.2560731093977517 1.040860046001058 1.3619388282193575e-17 0.514644326833172 0.0472869925632362 7.575749818146841 2.229311781933515 0.013811902163524434 16.745912197588215 0.00010957068364026501 3.9603056286652163 -1.040860046001058 SLS(ph)MVDLQDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSMVDLQDAR 11 0 A0A3B3ITG3;Q5VWQ8-2;Q5VWQ8;H0Y3A3;Q5VWQ8-3;Q5VWQ8-4;Q5VWQ8-5 A0A3B3ITG3 DAB2IP Disabled homolog 2-interacting protein 1 S(0.001)LS(0.999)MVDLQDAR;S(0.001)LS(0.999)MVDLQDAR 92.792 0.006563899999999999 12104500.0 72977.0 80634.0 96210.0 105649.0 127547.0 121533.0 119942.0 103923.0 113089.0 100526.0 True False 85330.56473854912 88638.81062845861 98504.01127845662 99729.82904867917 102555.08095380077 115159.59553338107 108580.2254551188 101195.13136552018 114742.7126816316 118750.5680366218 0.7185697394915518 0.7464285189871518 0.8295034954955222 0.8398261220773547 0.8636176032621043 0.969760376201878 0.9143554195179382 0.8521654509838837 0.9662498005588133 1.0 16.857574888946985 -2.843522939712216 0.26004570438990937 0.9743687248758437 6.9756318344033755e-12 0.8270380772086277 0.03701015159401693 10.96556969950669 0.2755340703004281 0.04909326812730509 4.11399568076684 0.0014337619818310542 2.843522939712216 -0.974368724868868 SLS(ph)MVDLQDAR ddPTM_PC-9_Lapatinib_30min_R1 3 SLSMVDLQDAR 11 0 A0A3B3ITG3;Q5VWQ8-2;Q5VWQ8;H0Y3A3;Q5VWQ8-3;Q5VWQ8-4;Q5VWQ8-5 A0A3B3ITG3 DAB2IP Disabled homolog 2-interacting protein 1 S(0.018)LS(0.982)MVDLQDAR;SLS(1)MVDLQDAR;S(0.007)LS(0.993)MVDLQDAR 148.13 0.00024202 16458500.0 132670.0 111329.0 121103.0 101057.0 127720.0 130501.0 112391.0 110781.0 141336.0 93516.0 True False 130778.1014713014 111071.22454053357 111146.37881109872 108489.06889626963 120207.7607071812 124919.77644268915 118210.05604661343 115928.28968592378 125417.2513459392 109680.1159977626 1.1923592556555027 1.0126833248681042 1.0133685381347157 0.9891407198956895 1.095984988834561 1.1389464289519664 1.077771070638044 1.0569672417951186 1.1434821180212613 1.0 16.742942476462616 SLS(ph)NPDIASETLTLLSFLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSNPDIASETLTLLSFLR 19 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 S(0.02)LS(0.979)NPDIAS(0.001)ETLTLLSFLR 77.39 0.0034279000000000002 9863500.0 2293.7 0.0 2240.7 2452.6 2370.6 2140.0 2441.3 873.5 822.09 1203.6 True False 2681.9781073599943 0.0 2294.126785902072 2315.1887734364823 1906.0979474944893 2027.7746327453074 2210.0423905185994 850.571550549753 834.1115110085188 1421.803152307642 1.8863216775170593 0.0 1.613533337704741 1.6283469126361414 1.3406201444980748 1.4261992804377666 1.554394071311218 0.5982343963503262 0.5866575198224334 1.0 10.473506023284772 -7.769150246429424 24.988768585199782 0.6943342844268001 1.3214210066186975 0.2486261857867591 0.49241083730678564 255.29478936613611 827323.4501839514 0.26107661175300284 0.12912750045967158 1.7015697396767052e-08 7.769150246429424 0.6270867221918974 SLS(ph)NPTPDYCHDK ddPTM_PC-9_AZD4547_30min_R2 2 SLSNPTPDYCHDK 13 0 Q8NG31-2;Q8NG31;Q8NG31-4;E9PPJ1;Q8NG31-3 Q8NG31-2 CASC5 Protein CASC5 1 S(0.364)LS(0.525)NPT(0.111)PDYCHDK;S(0.106)LS(0.676)NPT(0.218)PDYCHDK 114.96 0.00016814 7217100.0 53610.0 58883.0 71571.0 95131.0 78210.0 70403.0 61279.0 74207.0 54119.0 61554.0 True False 70656.8648427281 77915.77823017586 70621.92177633943 73200.01770929864 67351.89150286836 66000.68928048412 66732.71228684719 62740.01325721928 56979.61985387174 59399.013195579435 1.1895292706308207 1.3117352299040292 1.1889409937469335 1.2323440032291024 1.1338890644715423 1.1111411744024728 1.123464998772295 1.0562467267030033 0.9592687956996607 1.0 15.858151343072636 -7.098085782064837 0.569919464600473 0.9783184077821558 1.255809353195191 0.8272070787542232 0.042067852782784305 0.326836939476434 0.22337000479887056 0.03687318406942556 0.03256204174921436 7.978370825209624e-08 7.098085782064837 0.2774909454130352 SLS(ph)NSNPDISGTPTSPDDEVR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSNSNPDISGTPTSPDDEVR 21 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 S(0.013)LS(0.983)NS(0.004)NPDISGTPTSPDDEVR 254.54 7.817599999999997e-164 0.0 2641.1 5021.5 5205.5 3559.9 4405.6 5024.1 5155.3 5309.5 6225.1 3791.6 True False 2603.437429681578 5009.873025270043 4777.52388381109 3821.7069214782737 4146.471269742856 4809.230954749123 5422.216208923372 5556.198753282704 5523.963684790898 4446.9730080105755 0.5854403489726302 1.1265804888506148 1.0743316577827378 0.859395124412499 0.9324255538033603 1.0814616922760703 1.2193049517404395 1.2494338830647318 1.2421851166715607 1.0 12.118607932587967 -6.953798803869307 2.932511293287836 1.1970593799170608 0.9325675173193805 0.3987032400375028 0.15108292713629606 0.27440355617574846 4.809414332611536 0.05877294106133686 0.048936295294974355 1.1122468799040077e-07 6.953798803869307 -0.2644918625976803 SLS(ph)PDEER ddPTM_PC-9_AZD4547_30min_R2 2 SLSPDEER 8 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 S(0.002)LS(0.998)PDEER;S(0.371)LS(0.629)PDEER 90.82700000000001 0.0091832 33915000.0 142974.0 120853.0 188058.0 211758.0 151795.0 151302.0 123851.0 197563.0 144766.0 140469.0 True False 188436.75795605636 159916.36884077694 185564.22804508553 162940.4647284866 130720.8844224255 141841.06202172962 134873.4990688215 167034.17789610176 152418.03521435364 135551.2230654361 1.3901516614504488 1.1797486236149917 1.3689601897247812 1.202058240742163 0.9643652153497811 1.0464019343688045 0.9950002369488954 1.232258729347411 1.1244312796851361 1.0 17.0484786049675 -6.0238804032444 5.923973630987541 1.0686000012583565 1.2983964916727868 0.6210896535616477 0.08885118331990424 0.12517339007108869 14.971806620544173 0.026601989727139303 0.036256944647744364 9.464977736524341e-07 6.0238804032444 0.2297964904144303 SLS(ph)PDEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSPDEER 8 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 S(0.005)LS(0.995)PDEER;S(0.008)LS(0.992)PDEER 99.53 0.0051711000000000005 26066000.0 119100.0 159540.0 160803.0 179347.0 172535.0 157815.0 165523.0 142061.0 141847.0 134244.0 True False 139261.27766777508 175378.0768368717 164637.1533687731 169298.76904081955 138728.00530286087 149538.90358257038 149843.46315725608 138332.04927607122 143921.24402684078 158581.374525081 0.8781691928502595 1.1059185062690586 1.0381872011251507 1.0675829336694487 0.8748064248927282 0.9429789849558879 0.9448995104627314 0.8723095615128045 0.9075545249740437 1.0 17.274863810054754 -6.259369336658977 24.982553546920478 0.9193917533691449 1.0295485162391445 0.35279237530213703 0.06505284077308926 187.4641860721899 2262432.152096538 0.018876255071784934 0.023161038906972756 5.503394726437696e-07 6.259369336658977 0.11015676286999954 SLS(ph)PDEER ddPTM_PC-9_Lapatinib_30min_R1 2 SLSPDEER 8 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 S(0.015)LS(0.985)PDEER;S(0.003)LS(0.997)PDEER 99.788 0.0050921000000000004 36622000.0 221729.0 188739.0 208999.0 155443.0 179227.0 222125.0 215180.0 200300.0 191766.0 146138.0 True False 218567.10379988118 188301.98644158995 191815.90897947078 166874.79676264737 168685.22023383953 212625.2315486652 226320.9675161737 209606.66923110018 170167.2936944965 171397.75858335523 1.275203979365846 1.0986257229846663 1.1191272894399356 0.9736113129011065 0.9841740150400128 1.2405368267710455 1.320442982374871 1.2229253810758731 0.992820997783 1.0 17.386988717482197 -6.777552269790508 24.99435897273623 1.179596665664452 1.0857550408912082 0.04736721984830172 0.12354517398979395 573.4057298099277 889462.5079385064 0.04512591163106343 0.0399196912022375 1.6689669255394857e-07 6.777552269790508 -0.09384162477324387 SLS(ph)PFR ddPTM_PC-9_AZD4547_30min_R2 1 SLSPFR 6 0 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36;H0YMW2;H0YLH1 Q12802-2 AKAP13 A-kinase anchor protein 13 1 S(0.036)LS(0.964)PFR 86.47200000000001 0.040562 11333000.0 12342.0 11417.0 18210.0 24808.0 21100.0 18009.0 16967.0 19121.0 15624.0 18076.0 True False 16266.499270452328 15107.321978396472 17968.523501797376 19088.898879779255 18170.629212511496 16882.894383083654 18477.030130565694 16166.288806868472 16449.852742971812 17443.164741906203 0.9325428906471884 0.8660883619416836 1.030118316696799 1.0943483686718425 1.041704844354167 0.9678802346298702 1.0592705167873402 0.9267979203355163 0.9430543703719076 1.0 14.09037419393277 -5.26557147757586 24.9831042946522 1.009983058908283 0.8993156236490278 0.4159531222129791 0.051417983954736894 319.96777899148 1934570.947803532 0.014429377485597875 0.031895471416333636 5.425359516772052e-06 5.26557147757586 -0.11066743525925515 SLS(ph)PFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLSPFR 6 0 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36;H0YMW2;H0YLH1 Q12802-2 AKAP13 A-kinase anchor protein 13 1 S(0.036)LS(0.964)PFR;S(0.003)LS(0.997)PFR;S(0.015)LS(0.985)PFR 99.375 0.0351 46427300.0 64178.0 89099.0 86448.0 85089.0 105556.0 87309.0 90999.0 86271.0 74230.0 62058.3 True False 75042.06782672097 97944.15988522275 88509.24817586552 80321.73919226014 84873.05954008603 82730.36234128976 82378.91594429294 84006.47766168026 75315.47332063701 73308.9785367674 1.023640887167516 1.3360458956074501 1.2073452657845256 1.0956603242258458 1.1577444023110863 1.128516097108039 1.123722054086139 1.1459234508300729 1.0273703825086482 1.0 16.16170228319104 -8.174521406399506 0.43602440777927887 0.9901403664552513 1.1884741045203422 0.32094374883639354 0.07779931796000737 1.1988580488379301 0.6270541588266992 0.09338773254220765 0.05919809854514599 6.690808402007283e-09 8.174521406399506 0.19833373806509091 SLS(ph)PFR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSPFR 6 0 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36;H0YMW2;H0YLH1 Q12802-2 AKAP13 A-kinase anchor protein 13 1 SLS(1)PFR 96.19 0.034612000000000004 41122000.0 32432.0 24761.0 34759.0 30164.0 36756.0 36979.0 23479.0 29105.0 29811.0 24516.0 True False 31969.513732699594 24703.667425811294 31901.249193620144 32382.361184154208 34594.08434507637 35397.494372259265 24694.627736370676 30457.324553026294 26453.371256253144 28753.557934483404 1.1118454907578368 0.8591516737546007 1.1094713658152822 1.1262036252327186 1.2031236073080394 1.231064846058858 0.8588372886805442 1.059254114653394 0.9200034067619957 1.0 14.811452864192377 -7.267749529464178 24.98958683838 0.9644615529780199 1.1009332772228304 0.3198822600656963 0.10490359417689434 751.8577112351875 2977508.2807166344 0.046308424880152514 0.03210122215109724 5.398218640689774e-08 7.267749529464178 0.13647172424481047 SLS(ph)PGAASSSSGDGDGKEGLEEPK ddPTM_PC-9_AZD4547_30min_R2 1 SLSPGAASSSSGDGDGKEGLEEPK 24 1 Q6ZN18-2;Q6ZN18 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 S(0.044)LS(0.949)PGAAS(0.001)S(0.001)S(0.001)S(0.004)GDGDGKEGLEEPK 112.28 1.3215e-07 17290000.0 47368.0 53708.0 47092.0 40350.0 55476.0 47994.0 56346.0 52129.0 65228.0 54078.0 True False 62430.03868439365 71068.06068281662 46467.5293106338 31047.9309012856 47774.114985463915 44992.92759296559 61360.6848433344 44073.66085525061 68675.81891439873 52184.74568006215 1.1963273533446737 1.3618550738663286 0.8904427664651303 0.5949618130101927 0.9154804601015163 0.8621854338202843 1.175835659323296 0.8445698121336158 1.3160132912296092 1.0 15.671340528338169 -5.265297833973721 24.85468356588528 0.935410739103871 1.279091224446995 0.3275136545912175 0.18774258511279873 311.74227166132897 2008139.7801728032 0.04974592675761216 0.11017840107862821 5.428779046146679e-06 5.265297833973721 0.343680485343124 SLS(ph)PGAASSSSGDGDGKEGLEEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSPGAASSSSGDGDGKEGLEEPK 24 1 Q6ZN18-2;Q6ZN18 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 S(0.051)LS(0.914)PGAAS(0.019)S(0.004)S(0.004)S(0.007)GDGDGKEGLEEPK 97.085 2.4541e-06 8206000.0 39337.0 56231.0 35316.0 45941.0 45321.0 30670.0 43848.0 35308.0 27023.0 29878.0 True False 45995.977158835085 61813.24206226741 36158.06737667584 43367.074712731606 36440.675389520686 29061.61120855071 39694.40000797095 34381.202411918326 27418.160252506677 35294.64488588213 1.3031998850690658 1.7513490293535359 1.0244632717962003 1.2287154284438897 1.032470379213164 0.823400017269344 1.1246578662659594 0.9741195165182358 0.7768362691042104 1.0 15.107161685350336 -5.580696603086714 1.2613111491627818 0.95880944711304 1.5358579583723684 0.5701520822788938 0.17341598597240085 0.36596751140816564 1.0751513354060334 0.05578179672743971 0.18875834754519694 2.6260524556451483e-06 5.580696603086714 0.5770485112593284 SLS(ph)PGGAALGYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSPGGAALGYR 12 0 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 S(0.284)LS(0.716)PGGAALGYR;S(0.009)LS(0.969)PGGAALGY(0.023)R 76.165 0.018953 5825800.0 24854.0 29366.0 29276.0 32191.0 41054.0 29488.0 30925.0 25976.0 27889.0 25321.0 True False 29061.291311124063 32281.26240686709 29974.050869848288 30387.44263463013 33009.76340860491 27941.597369342817 27995.560122388735 25294.157523847036 28296.823864195627 29911.496859074276 0.9715759611778745 1.079225909654665 1.0020913032560266 1.0159118006630774 1.103581126819827 0.934142396851201 0.9359464775128998 0.8456332908720189 0.9460183152155154 1.0 14.868412488506491 -6.8782553828338315 7.688231638508045 0.9214153740526491 1.0339160146861972 0.5070701050872577 0.04989435702558008 0.17565309163403853 11.108250030256906 0.01698332679528355 0.014984607321299566 1.32356299739147e-07 6.8782553828338315 0.11250064063354814 SLS(ph)PGGAALGYR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSPGGAALGYR 12 0 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 S(0.077)LS(0.923)PGGAALGYR 106.26 0.0016928000000000002 25952000.0 47217.0 37617.0 44341.0 35610.0 49963.0 32517.0 36311.0 41170.0 42108.0 50041.0 True False 46543.6769214627 37529.900147681576 40695.4541412098 38228.87819147766 47024.274571037386 31126.323710829267 38191.005908912455 43082.908498474266 37365.35362310247 58690.52017455881 0.7930356858830239 0.6394542088919848 0.6933905853990109 0.6513637650130955 0.8012243618079481 0.5303467002550425 0.6507184771122119 0.734069290412421 0.6366505785256205 1.0 15.84083987433925 -10.78410608529458 4.065383866901874 1.0003178104291133 0.6791567161278382 0.6111613915240521 0.07628603210923965 34065189.465308554 54.971442168036496 101514.00258138492 0.018050627817901368 1.6439701009011653e-11 10.78410608529458 -0.32116109430127504 SLS(ph)PGVSR ddPTM_PC-9_AZD4547_30min_R2 3 SLSPGVSR 8 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 S(0.031)LS(0.969)PGVSR;S(0.03)LS(0.97)PGVS(0.001)R;S(0.009)LS(0.988)PGVS(0.002)R 97.565 0.0057740000000000005 71019000.0 242537.0 229175.0 378375.0 456420.0 412910.0 318135.0 283480.0 473082.0 272995.0 315951.0 True False 319658.72091700643 303251.3369886143 373357.5002741666 351199.42061870586 355584.5738454092 298241.9681582717 308709.17082647287 399978.04724287207 287424.9583696617 304889.6516579991 1.048440703640457 0.9946265323848298 1.2245659970544664 1.1518902616368671 1.166273016849636 0.9781964279089923 1.0125275461062817 1.311878068238064 0.9427179860209625 1.0 18.217927658713478 -6.725952661942023 24.999801988798733 1.0662724812193312 1.1182484155077868 0.07451074045555939 0.11203698615917387 672.6928786069132 473898.70488336193 0.037734737486457275 0.037733287750540544 1.8795216733252932e-07 6.725952661942023 0.051975934288455594 SLS(ph)PGVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLSPGVSR 8 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 S(0.129)LS(0.87)PGVS(0.001)R;S(0.224)LS(0.776)PGVSR;S(0.223)LS(0.777)PGVSR;S(0.004)LS(0.996)PGVSR 120.27 0.003423 62458000.0 312613.0 346590.0 535325.0 359634.0 436226.0 347753.0 353907.0 345629.0 329718.0 251512.0 True False 365532.2065118066 380997.1646664869 548089.1782313689 339484.8729291589 350750.64677454357 329516.22049583093 320382.36689520604 336556.60497419594 334539.501984827 297109.1346321033 1.2302960895646256 1.2823475290931674 1.8447402464082523 1.1426268443396315 1.1805448095995503 1.1090746869962642 1.0783322676763907 1.1327709778796893 1.125981880022208 1.0 18.180633436008144 -5.958613711135961 24.999948769581884 1.1147023172508115 1.445155965908776 0.4952303128737111 0.15863132161866367 125.82604814751747 76006.14047314908 0.04468599815165157 0.06627997331408454 1.0999837993064938e-06 5.958613711135961 0.33045364865796456 SLS(ph)PGVSR ddPTM_PC-9_Lapatinib_30min_R1 3 SLSPGVSR 8 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 S(0.046)LS(0.954)PGVSR;S(0.046)LS(0.954)PGVSR;S(0.315)LS(0.685)PGVSR 104.42 0.0038583 59309000.0 225082.0 272987.0 332944.0 275012.0 301043.0 312228.0 289679.0 272934.0 325104.0 262438.0 True False 221872.28940501646 272354.91537377157 305570.6295210064 295237.29989313893 283336.2426133098 298874.73627901665 304677.1612097671 285615.5100345536 288487.36402310955 307800.0586233468 0.7208325118499095 0.8848436111152622 0.9927568918852335 0.9591853270386123 0.9205204309594587 0.9710028569057162 0.9898541363911787 0.9279254569085696 0.9372557150033877 1.0 18.231633980877476 -4.821372958021279 2.7224532820612306 0.9591726620843681 0.6863695130065878 0.8831356067162728 0.02667541089505191 0.12605916837696837 1.3522933527407075 0.00695621566097878 0.07568463637876868 1.5087839029533052e-05 4.821372958021279 -0.27280314907778036 SLS(ph)PIIGK ddPTM_PC-9_AZD4547_30min_R2 1 SLSPIIGK 8 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 S(0.34)LS(0.66)PIIGK 101.46 0.0045792 167180000.0 117800.0 152950.0 190950.0 193520.0 183810.0 205150.0 185100.0 244950.0 161620.0 184530.0 True False 155257.949607785 202388.09639973182 188417.87823548663 148906.95385419542 158291.15429155165 192321.93806927704 201573.54141378574 207098.60589103264 170162.90324623047 178069.66086656033 0.8718944532843824 1.1365669784219725 1.0581133098056548 0.8362286597815307 0.888928262800309 1.0800376500598656 1.1319926170064336 1.163020162352225 0.9555973904715025 1.0 17.44208220847389 -6.7930662276272615 23.383052355398966 1.080434971702338 0.9670058077171838 0.21517847431262782 0.10041383304982526 157.69290622641714 116587.10101433066 0.0372636301144025 0.032868087587209396 1.6104000389057283e-07 6.7930662276272615 -0.11342916398515424 SLS(ph)PIIGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSPIIGK 8 0 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 S(0.009)LS(0.991)PIIGK;S(0.101)LS(0.899)PIIGK 106.18 0.0038301999999999998 10083300.0 71620.0 88131.0 100211.0 102971.0 126910.0 86633.0 100746.0 91603.0 88659.0 77952.0 True False 83743.85144052088 96880.06324251187 102600.41029233404 97201.8687064864 102042.89653105763 82089.81297131971 91202.60954212361 89198.51831140133 89955.47014865075 92084.08053230765 0.9094281113133273 1.0520826475377745 1.1142035593908846 1.05557733915129 1.1081491604323066 0.8914658483506119 0.9904275420345346 0.9686638319650277 0.9768840567082594 1.0 16.490664144745132 -6.754280669539053 24.999994094369974 0.9650884488064373 1.0522325481402852 0.32658606387469 0.05899534671462681 197.5348721561824 689840.1957783321 0.019970709563393738 0.01956745079890309 1.7608377099602603e-07 6.754280669539053 0.08714409933384792 SLS(ph)PIIGKDVLTSTYGATAETLSTSTTTHVTK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSPIIGKDVLTSTYGATAETLSTSTTTHVTK 32 1 A0A0C4DH22;A0A1B0GTW6;Q9H4G0-3;Q9H4G0-2;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15 A0A0C4DH22 EPB41L1 Band 4.1-like protein 1 1 S(0.044)LS(0.641)PIIGKDVLT(0.173)S(0.044)T(0.044)Y(0.04)GAT(0.012)AET(0.002)LSTSTTTHVTK 62.052 0.00017138 1458000.0 10810.0 1214.1 4961.8 2573.6 2706.7 2822.3 602.93 1087.7 6279.4 1885.7 True False 10655.847417688794 1211.2888260440811 4553.859957101886 2762.8711292779235 2547.4972275769464 2701.596808102634 634.1467652408525 1138.2385128440717 5572.147846986549 2211.640732462691 4.818073415487952 0.5476878808861939 2.059041457439203 1.2492404795789007 1.1518585230342882 1.2215351112178017 0.28673136460763304 0.5146579623611056 2.5194633853491606 1.0 11.110901332264282 -4.755563539118601 24.999957167637636 1.1604284671970682 4.8180793280231 0.737945011585293 0.651746439793703 96.70798861232257 411422.7563698105 0.16011416358601932 1.4035484555107476 1.75564401726713e-05 4.755563539118601 3.657650860826032 SLS(ph)PILPGR ddPTM_PC-9_AZD4547_30min_R2 2 SLSPILPGR 9 0 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 SLS(1)PILPGR;S(0.36)LS(0.64)PILPGR 110.53 0.0022954 94588000.0 524280.0 457830.0 431740.0 504510.0 480770.0 422910.0 398660.0 466320.0 328330.0 338860.0 True False 690990.1342985552 605814.5941463826 426014.8455060955 388203.01410179946 414023.3841942732 396465.3708451285 434139.9676932472 394260.95896756946 345684.85350101977 326996.61454095744 2.11314155428972 1.8526631995772613 1.302811180795071 1.187177471689621 1.2661396656215698 1.2124448792893232 1.3276589065079438 1.2057034887686489 1.0571511695504774 1.0 18.31891617373737 -5.171209004331393 2.1915910850323455 1.1968461522514482 2.122282680456898 0.9264353491684425 0.09074052966061652 0.08552985373337697 0.7316808648385222 0.02486753283728054 0.11045683262371854 6.742034890091015e-06 5.171209004331393 0.92543652820545 SLS(ph)PILPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSPILPGR 9 0 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 S(0.013)LS(0.987)PILPGR;S(0.221)LS(0.779)PILPGR 90.82700000000001 0.0082729 63873000.0 58160.0 64475.0 65807.0 73332.0 67960.0 66319.0 76100.0 57336.0 65948.0 52928.0 True False 68005.33928763882 70875.65189956946 67376.0884544372 69223.4457855516 54643.72585494194 62841.11489207283 68891.25708371162 55830.99075251362 66912.36473864163 62523.42742218257 1.0876777248380876 1.1335855186087196 1.077613483974376 1.1071601260456803 0.8739720150970962 1.0050810949269482 1.1018470983449289 0.8929611355999567 1.0701966846254802 1.0 15.932109246010073 -6.1449941623370234 19.94195011634795 0.9914624281185945 1.1021118948447193 0.40129313487011453 0.06631346996386676 4.689213649007899 788.7331139589484 0.019054577352755245 0.024599461442259135 7.161530364737533e-07 6.1449941623370234 0.11064946672612475 SLS(ph)PILPGR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSPILPGR 9 0 M0QZS0;A0A590UK10;A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-2;Q6ZSZ5-1;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 M0QZS0 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 S(0.002)LS(0.998)PILPGR 107.45 0.0025013 38158000.0 122010.0 109200.0 111260.0 106330.0 99878.0 102680.0 96297.0 81501.0 95689.0 65099.0 True False 120270.11502610637 108947.15410922818 102112.6322760201 114149.86290648184 94003.37240770327 98288.61575877074 101282.78747516031 85287.83399402854 84911.4971701588 76351.27541103502 1.5752207723922813 1.4269198978368618 1.337405717537782 1.4950616383545545 1.2311958366332278 1.2873212036031703 1.3265369429640457 1.1170453084756449 1.1121162903047794 1.0 16.220364636293997 -6.132765137812928 0.1995005530621585 0.9198552685632485 1.7962511223632014 0.8260529737459346 0.07161507552623246 3.231857667054672 0.21970590063819379 0.20622075996071468 0.7635218152900525 7.366053387295454e-07 6.132765137812928 0.8763958537999529 SLS(ph)PLIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSPLIK 7 0 Q5VY60;Q7Z4H7-3;Q7Z4H7 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 S(0.002)LS(0.998)PLIK 97.635 0.012421 8533900.0 75887.0 82993.0 78030.0 101670.0 101390.0 99224.0 97570.0 102290.0 96436.0 80411.0 True False 88733.17026342954 91231.99655837096 79890.53113042282 95973.75951858728 81523.35733420486 94020.51876613087 88327.46325437252 99604.99588521363 97846.19406101215 94988.87776687401 0.9341427370181432 0.9604492515668691 0.8410514263206033 1.0103683902249105 0.8582410830695691 0.9898055538342108 0.9298716368788961 1.0485964065147575 1.0300805353354179 1.0 16.53547097794094 -7.755323467147559 24.977340181457123 1.0295038599762867 0.9319886782437614 0.4244003166179263 0.05024831058864377 122.65564852924723 500930.8444975132 0.022749011911313583 0.01269701098262308 1.7566147812374676e-08 7.755323467147559 -0.09751518173252527 SLS(ph)PLIK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSPLIK 7 0 Q5VY60;Q7Z4H7-3;Q7Z4H7 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 S(0.086)LS(0.914)PLIK 69.598 0.046141 7718900.0 49743.0 40526.0 38791.0 36057.0 37064.0 34834.0 39730.0 35329.0 35027.0 29356.0 True False 49033.65569825101 40432.16453691002 35601.75371759022 38708.75206262594 34883.96839062768 33344.23102202005 41787.02499961702 36970.51431485542 31081.890409338135 34430.14548558878 1.4241489545484127 1.1743245335351102 1.0340285588538054 1.1242691983055382 1.0131809755270669 0.9684603579725433 1.2136755279499927 1.0737832731589807 0.9027522239877812 1.0 15.071384656620333 -4.699496234495778 1.7388303186750347 1.0472600097485112 1.6121486017935205 0.6763030565628241 0.08093907553889475 0.7000697802551042 1.8158429867641268 0.022516113703236553 0.7054193277044852 1.9975780881564707e-05 4.699496234495778 0.5648885920450093 SLS(ph)PNHNTLQTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSPNHNTLQTLK 13 0 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 S(0.021)LS(0.979)PNHNTLQTLK;S(0.164)LS(0.836)PNHNTLQTLK 122.08 0.00010618 37804000.0 117512.0 177029.0 435820.0 421710.0 557960.0 493200.0 404510.0 354100.0 408940.0 307320.0 True False 137404.46063220463 194603.26917609776 446211.6016565529 398082.95590226655 448631.7433493747 467335.72377102135 366191.88440121163 344805.25019996334 414919.97386152827 363034.6832562183 0.3784885218121954 0.536045943133078 1.2291156251361002 1.0965424910140398 1.2357820451902792 1.2873032394020345 1.0086966928797958 0.9497859739109576 1.1429210293075247 1.0 18.469747860044784 -5.181398168464355 4.6163722411120185 1.1223625626261364 0.4216789065613622 0.8578001834995761 0.1081591202914775 0.0770995754104371 2.9632917783479096 0.02982397756548439 0.0852291134647816 6.585698305131199e-06 5.181398168464355 -0.7006836560647742 down SLS(ph)PPQSQSK ddPTM_PC-9_AZD4547_30min_R2 1 SLSPPQSQSK 10 0 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L0Y9;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 S(0.314)LS(0.686)PPQSQSK 99.73200000000001 0.0042602 142360000.0 174960.0 159560.0 215600.0 333210.0 304350.0 269590.0 221410.0 231180.0 201620.0 265890.0 True False 230593.6406059259 211134.64963413696 212741.00312946265 256393.58254318187 262096.2559634063 252732.4946824096 241115.06107199623 195456.44298791137 212277.22158461192 256581.2720306172 0.8987157900534913 0.8228763072347026 0.8291369102889037 0.9992684988816607 1.0214941016121044 0.9849997729072435 0.9397219803447875 0.7617720554623646 0.82732936782417 1.0 17.969056345820817 -5.735999412879873 24.963066592278636 0.9296560763898687 0.8475062940537155 0.18493879056905604 0.0797589663523646 449.2795549862188 440853.7988177501 0.024612014571064957 0.04260880003301124 1.8365408261552876e-06 5.735999412879873 -0.08214978233615322 SLS(ph)PPQSQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSPPQSQSK 10 0 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L0Y9;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 S(0.021)LS(0.979)PPQSQSK 101.35 0.0036361999999999996 92209000.0 30365.0 24452.0 37632.0 40583.0 43604.0 40629.0 33881.0 50798.0 37984.0 25634.0 True False 35505.19476391255 26879.432962361716 38529.28960015473 38309.26608186122 35060.109213933065 38498.3437167332 30671.546402802058 49464.60632492997 38539.444141331944 30281.24128136764 1.1725145093625757 0.8876595484512357 1.2723814470532355 1.265115446421059 1.1578161175151664 1.271359498080471 1.0128893369267058 1.6335065615479263 1.2727167880348969 1.0 14.886136724693738 -5.283121767098951 24.526875409987266 1.2499301066332849 1.0300870161746007 0.17261833473384147 0.17791952446496637 862.9092160306076 976112.4663457242 0.045559694871788355 0.09497502920228677 5.210485994817602e-06 5.283121767098951 -0.2198430904586841 SLS(ph)PQDR ddPTM_PC-9_AZD4547_30min_R2 1 SLSPQDR 7 0 E9PKP7;P17480-2;P17480 E9PKP7 UBTF Nucleolar transcription factor 1 1 SLS(1)PQDR 73.233 0.036802999999999995 7920000.0 45798.0 39347.0 44587.0 76359.0 64974.0 58372.0 36289.0 74350.0 48696.0 59359.0 True False 60360.81134242232 52065.14827747797 43995.74724737175 58755.61228478978 55953.48163287782 54721.98961238041 39518.65069889188 62860.91589303237 51269.971145145675 57280.85947747345 1.0537693025741017 0.9089449556523042 0.7680706548174915 1.0257459964946283 0.9768268518191903 0.9553276628801396 0.6899102258483599 1.097415724318057 0.8950628816124582 1.0 15.80576551940347 SLS(ph)PQEDALTGSR ddPTM_PC-9_AZD4547_30min_R2 2 SLSPQEDALTGSR 13 0 Q96EN8 Q96EN8 MOCOS Molybdenum cofactor sulfurase 1 SLS(1)PQEDALTGSR;SLS(1)PQEDALTGSR 197.73 7.9429e-07 72809000.0 89459.0 87643.0 104757.0 145450.0 123308.0 121937.0 93027.0 126958.0 108247.0 105029.0 True False 117905.10113720583 115971.88579772289 103367.85373299211 111918.74968009902 106188.81265101283 114312.26011383571 101306.22278282142 107339.55830460772 113968.71542936965 101351.9666783396 1.1633232684216268 1.1442489928763049 1.0198899648494275 1.104258292641673 1.0477232571916826 1.1278741188775168 0.9995486629710566 1.0590772120413896 1.124484498569937 1.0 16.629014558205206 -5.138264687869485 5.938536133238525 1.063986681068691 1.1582725402432414 0.41230214556943834 0.04462591583732934 0.20923288842860654 9.126819337327506 0.010800467290343762 0.02977718580380767 7.2733638238032e-06 5.138264687869485 0.09428585917455035 SLS(ph)PQEDALTGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSPQEDALTGSR 13 0 Q96EN8 Q96EN8 MOCOS Molybdenum cofactor sulfurase 1 S(0.198)LS(0.802)PQEDALTGSR;S(0.081)LS(0.919)PQEDALTGSR 178.47 0.00012374 21693400.0 58657.0 72047.0 67716.0 70838.0 80296.0 56636.0 68704.0 64599.0 50256.0 51095.0 True False 68586.47157144149 79199.35001796487 69330.60625435993 66869.17651989475 64562.575209659 53665.908458020174 62195.85974611467 62903.34469829823 50990.898924988935 60358.11903220258 1.1363255295422456 1.3121573582455415 1.148654188798864 1.107873763995501 1.069658502366736 0.8891249316332747 1.030447282708257 1.042168737311673 0.8448059638469516 1.0 15.881260226746111 -6.10064436381137 1.3233540002656583 0.9682871320736581 1.2221818416505597 0.6604895468015217 0.07368399522265509 0.2591716127304285 0.9197579218852865 0.026973230636670894 0.044740859390881765 7.931505618055887e-07 6.10064436381137 0.2538947095769015 SLS(ph)PQEDALTGSR ddPTM_PC-9_Lapatinib_30min_R1 2 SLSPQEDALTGSR 13 0 Q96EN8 Q96EN8 MOCOS Molybdenum cofactor sulfurase 1 S(0.215)LS(0.785)PQEDALTGSR;S(0.372)LS(0.628)PQEDALTGSR 212.35 6.4727e-11 33784400.0 77332.7 69223.0 74251.0 59063.6 73717.4 70844.4 61825.5 79763.0 60867.8 60083.4 True False 76229.92151691962 69062.71839654831 68146.36939714855 63407.33417439373 69381.48746598467 67814.5501583625 65026.52187550521 83469.08016914749 54012.22739765073 70468.73563390195 1.0817552043639338 0.9800476448923654 0.9670440200769528 0.899793839126141 0.9845711980194205 0.9623352760388887 0.9227712302563503 1.1844838625001692 0.7664707889503537 1.0 16.104695708690056 -4.7531757325153166 3.4730923738570443 0.9651849866493736 1.1003375117468595 0.11892900984704646 0.09759929564068098 0.739441004820218 13.924730908841008 0.02294873377638923 0.2761578397015891 1.765323357344241e-05 4.7531757325153166 0.13515252509748588 SLS(ph)PSHLTEDR ddPTM_PC-9_AZD4547_30min_R2 4 SLSPSHLTEDR 11 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 S(0.001)LS(0.453)PS(0.255)HLT(0.29)EDR;S(0.01)LS(0.749)PS(0.041)HLT(0.2)EDR;S(0.069)LS(0.928)PS(0.003)HLTEDR;S(0.012)LS(0.905)PS(0.064)HLT(0.019)EDR 115.24 0.00078145 159013100.0 34903.2 28691.8 65097.0 109435.0 88016.5 65474.3 53991.9 79380.0 56679.5 74643.9 True False 46001.691568339964 37965.86325127052 64233.771246375814 84206.45150389575 75796.92825037993 61380.18167062768 58797.074503830416 67113.64497093367 59675.46265650741 72030.63978083503 0.638640607778962 0.5270793563237514 0.891756222654936 1.1690365622200165 1.0522873110804576 0.8521398929314927 0.8162786653392238 0.9317374547156305 0.8284733113308411 1.0 16.136323098007182 -5.32437888216239 5.388781427480767 0.9469915956146501 0.583159735050914 0.6520908430673173 0.10549402119899234 0.12608447284515886 7.411239326455445 0.030619442069504066 0.06664878530743157 4.738284329790789e-06 5.32437888216239 -0.36383186056373606 SLS(ph)PSHLTEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SLSPSHLTEDR 11 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 S(0.182)LS(0.612)PS(0.073)HLT(0.133)EDR;S(0.001)LS(0.991)PS(0.006)HLT(0.003)EDR;S(0.311)LS(0.688)PS(0.001)HLTEDR;S(0.352)LS(0.635)PS(0.013)HLTEDR;S(0.036)LS(0.914)PS(0.05)HLTEDR 120.6 0.00048182 83395700.0 59788.4 69994.8 113514.0 108067.0 117398.0 117112.0 102972.0 101183.0 104402.0 87010.0 True False 69909.3952452729 76943.42116448213 116220.60426424237 102012.35634794123 94394.70464859452 110970.4405561066 93217.74670727926 98527.05346225035 105928.68174082105 102784.22422921911 0.6801568603501638 0.748591739067764 1.1307241469766682 0.9924904051466445 0.9183773614721737 1.0796446768779555 0.9069265970174019 0.9585814768862306 1.030592802885679 1.0 16.64925932483625 -5.128777979657026 5.686999547595554 0.9961305267766525 0.6973778215076868 0.7589109129477093 0.06519296661183295 0.09925856100221801 4.08677485213971 0.01651653115337318 0.04594888103977458 7.433990817936451e-06 5.128777979657026 -0.2987527052689657 SLS(ph)PSHLTEDR ddPTM_PC-9_Lapatinib_30min_R1 3 SLSPSHLTEDR 11 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 S(0.019)LS(0.946)PS(0.018)HLT(0.018)EDR;S(0.072)LS(0.904)PS(0.024)HLTEDR;S(0.06)LS(0.938)PS(0.002)HLTEDR 123.68 0.00031162 102133700.0 66016.0 44779.4 93541.0 55183.0 68337.0 76991.0 53046.1 60241.2 78685.0 46131.6 True False 65074.59973414836 44675.716050538125 85850.42005870212 59241.34190509161 64317.55201571129 73698.27440478685 55792.56750143928 63040.22607331281 69822.66671021702 54105.38559350685 1.202737934871273 0.8257166187888628 1.586725962988146 1.0949250477608854 1.1887458394424602 1.3621245574050826 1.0311832526360352 1.1651377285605784 1.2904938379848898 1.0 15.723484585104949 -9.762521131033955 8.737953493977088 0.9999987984791742 1.1911156279088926 0.08492816711180562 0.19099491962757717 0.0 0.0 0.17693377866437396 0.04291274459840414 1.727741913445618e-10 9.762521131033955 0.19111682942971842 SLS(ph)PSLLGYQQPALMAAPLSLADAHR ddPTM_PC-9_AZD4547_30min_R2 1 SLSPSLLGYQQPALMAAPLSLADAHR 26 0 Q13469-3;Q13469-4;Q13469-2;Q13469;Q13469-5 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 S(0.156)LS(0.689)PS(0.156)LLGYQQPALMAAPLSLADAHR 106.37 5.804500000000001e-10 9545200.0 5384.7 2292.2 5811.8 6888.0 8000.8 9923.8 4552.3 6315.9 5044.2 8763.9 True False 7096.922591282178 3033.1088235859143 5734.731734637341 5300.078018539162 6890.027023860759 9303.263217216145 4957.445881026361 5339.9227799435475 5310.826114061599 8457.078528523554 0.8391695273191658 0.3586473524345336 0.6780984373380906 0.6267031813247754 0.8147053383295978 1.1000563830451173 0.5861889379773605 0.6314145909764654 0.6279740806650365 1.0 13.045943659553314 -6.2043017865828025 5.921921076345241 0.7798030870838835 0.6086095354409244 0.15529008022671842 0.18855149960334916 0.44680475605931586 34.132957942267545 0.057552844683525714 0.07421834924227846 6.24738417873023e-07 6.2043017865828025 -0.17119355164295902 SLS(ph)PSLLGYQQPALMAAPLSLADAHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSPSLLGYQQPALMAAPLSLADAHR 26 0 Q13469-3;Q13469-4;Q13469-2;Q13469;Q13469-5 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 S(0.202)LS(0.742)PS(0.057)LLGYQQPALMAAPLSLADAHR 106.32 5.845800000000001e-10 5644700.0 4440.9 4489.8 8530.1 11130.0 10614.0 13235.0 11927.0 11464.0 11615.0 7739.3 True False 5192.656658226883 4935.517671945509 8733.489934584393 10506.42218394686 8534.26289323652 12540.933301114082 10797.188215997758 11163.082147112043 11784.847401578838 9142.373825734905 0.5679768468458436 0.5398507833985634 0.9552759601669817 1.1492006763464746 0.9334843505538342 1.371737093687042 1.1810048923622778 1.2210266567408388 1.2890358266039859 1.0 13.158353095674435 -5.414385377415234 1.5693007225061202 1.18626516522255 0.49372276968240986 0.790651158517821 0.12328832089846835 0.18980875160842922 0.8417553086735502 0.03684320397205267 0.137467326810947 3.8513644965694925e-06 5.414385377415234 -0.6925423955401402 SLS(ph)PSPLGSSAASTALER ddPTM_PC-9_AZD4547_30min_R2 1 SLSPSPLGSSAASTALER 18 0 A0A0C3SFZ9;M0QZI3;O14526-3;O14526-2;O14526 A0A0C3SFZ9 FCHO1 F-BAR domain only protein 1 1 S(0.06)LS(0.635)PS(0.301)PLGS(0.002)S(0.002)AASTALER 91.37100000000001 0.0091541 0.0 7914.6 6429.8 7757.1 11771.0 9196.0 11802.0 10165.0 9245.8 13828.0 6910.4 True False 10431.278166093181 8508.107108407956 7654.235785600904 9057.37781013712 7919.294134514492 11064.0190743047 11069.665307785725 7817.0740573476605 14558.9198495785 6668.468999362059 1.5642688249868288 1.275871134622038 1.147825053446773 1.3582394716093902 1.1875730599140664 1.6591543089370504 1.6600010150522868 1.172244192496881 2.1832477366200975 1.0 12.703139858581425 -6.762238974856289 24.99963082177794 1.5535116896271084 1.2990704575939511 0.11558186857265418 0.3131268497165288 43.377605794765756 1356181.995525146 0.10055887733586151 0.09391021138992839 1.7288647724002062e-07 6.762238974856289 -0.25444123203315727 SLS(ph)PSSNSAFSR ddPTM_PC-9_AZD4547_30min_R2 2 SLSPSSNSAFSR 12 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 S(0.353)LS(0.589)PS(0.002)S(0.002)NS(0.053)AFSR;S(0.007)LS(0.966)PS(0.004)S(0.004)NS(0.019)AFSR 130.19 0.00015337 115969000.0 147313.0 130577.0 193397.0 272223.0 224393.0 167924.0 177997.0 234144.0 162975.0 186078.0 True False 194155.4696992497 172783.46167759286 190832.42941664485 209466.19315342413 193239.9052551229 157423.68573407442 193838.38817412086 197962.42489385518 171589.52577994321 179563.46585773485 1.081263768060012 0.9622417391658409 1.0627575520726371 1.1665301299061621 1.0761649332845005 0.8767022009855757 1.0794979215187115 1.102464935994817 0.95559263662181 1.0 17.454134322358435 SLS(ph)PSSNSAFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSPSSNSAFSR 12 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 S(0.015)LS(0.59)PS(0.141)S(0.241)NS(0.013)AFSR 81.789 0.012819999999999998 43696000.0 65689.0 64381.0 65645.0 82225.0 73756.0 62268.0 78117.0 74567.0 65532.0 52763.0 True False 76808.85028311053 70772.32020079372 67210.22576004874 77618.19982704663 59304.04126187615 59002.55646345082 70717.19224189618 72609.69526026714 66490.2815256362 62328.514228321816 1.2323228177996406 1.1354726015374048 1.0783222830219286 1.2453080389934474 0.9514752917843281 0.9466382633045392 1.1345881273993625 1.1649514858365355 1.0667714825042836 1.0 15.92760470210123 -3.2531118109560073 0.6234201765103269 1.0662296134254758 2.2165922229148647 0.26193484752901597 0.08687423525144684 31.75702150873357 2.06631491038444 0.041012771841606094 39.833886572504454 0.0005583264327238469 3.2531118109560073 1.1503626094893888 SLS(ph)PSSNSAFSR ddPTM_PC-9_Lapatinib_30min_R1 2 SLSPSSNSAFSR 12 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 S(0.002)LS(0.853)PS(0.062)S(0.062)NS(0.02)AFSR;SLS(0.755)PS(0.016)S(0.016)NS(0.212)AFSR 95.18299999999999 0.0046758 108752000.0 100865.0 88292.0 91043.0 64398.0 86923.0 69894.0 75095.0 63705.0 87538.0 46258.0 True False 99426.64660362447 88087.56529864449 83557.79597614308 69134.04374543035 81810.36003719318 66904.7965508718 78983.0516573431 66664.96686653634 77678.54862399404 54253.63366508946 1.8326264968239805 1.6236251721389516 1.5401327124363644 1.2742749024369213 1.5079240690533808 1.2331855404170464 1.4558112760688 1.228765012829605 1.4317667477077722 1.0 15.727432145586732 -1.5228787452803376 0.25773605473562206 1.1931035888557737 5.201972863339869 0.6796261215538846 0.1270572111612007 29.941035144410307 0.41187772131012507 0.14983908479122598 52.56405755711895 0.029999999999999995 1.5228787452803376 4.008869274484096 SLS(ph)PSVR ddPTM_PC-9_AZD4547_30min_R2 1 SLSPSVR 7 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 S(0.029)LS(0.97)PS(0.001)VR 93.14299999999999 0.014112999999999999 16455000.0 15790.0 15116.0 24884.0 37103.0 28110.0 29495.0 19441.0 29251.0 25750.0 28931.0 True False 20810.89154759701 20001.951390508966 24554.02190108324 28549.47658563569 24207.411713919366 27650.67298734259 21171.21133779264 24730.9300711108 27111.092430333105 27918.13449591105 0.7454255781540495 0.7164501408014384 0.8795008099369775 1.0226140500117264 0.8670855754156795 0.9904197929626124 0.758331877113545 0.8858374858367756 0.9710925504103383 1.0 14.76891492269391 -5.335018584108384 4.502257667239706 0.9181156459870972 0.7304060839036901 0.5153400433869925 0.07464255283486276 0.16690537068720437 6.367193225738605 0.01977106697471762 0.04436706325327625 4.623612358493061e-06 5.335018584108384 -0.18770956208340706 SLS(ph)PSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSPSVR 7 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 S(0.04)LS(0.959)PS(0.001)VR 74.301 0.034381999999999996 11957000.0 12613.0 14593.0 15724.0 22585.0 23449.0 19708.0 19876.0 20224.0 13423.0 16778.0 True False 14748.131781894577 16041.69659822282 16098.919793602068 21319.635671557946 18854.336780054953 18674.477786048825 17993.201390221464 19693.141429099247 13619.285981178882 19819.718585425075 0.7441140860970642 0.8093806442852061 0.8122678293444999 1.0756780213436468 0.9512918510316267 0.9422171008917134 0.9078434344397409 0.99361357449248 0.6871583934190753 1.0 14.274648857800694 -5.549898685271125 24.567884762573886 0.93678156353788 0.7852665220835361 0.3369444987612561 0.09601193880553478 190.64433298202712 173342.4194187071 0.02542105832604291 0.04403201912012165 2.8190404966346818e-06 5.549898685271125 -0.1515150414543439 SLS(ph)PSVR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSPSVR 7 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 S(0.002)LS(0.995)PS(0.003)VR 105.14 0.010247 16001000.0 27445.0 25491.0 32100.0 21711.0 27951.0 28783.0 26462.0 25736.0 33444.0 20333.0 True False 27053.629267203403 25431.97715566236 29460.861909583313 23307.69936577286 26306.977133780336 27552.01818645012 27832.072880439606 26931.78851388715 29677.184539067126 23847.53195798053 1.1344414723868295 1.0664406363087648 1.2353841043800047 0.9773631672594524 1.1031320633151205 1.1553404450824059 1.1670839955044345 1.1293323167085423 1.244455174286315 1.0 14.541552345309574 -6.754874172571065 21.844976403298972 1.1490657587969089 1.1016372974004716 0.03865458284005063 0.08229374259459617 93.58782432819476 311398.8125187379 0.026353950918445578 0.025662833079977947 1.7584330080775576e-07 6.754874172571065 -0.047428461396437305 SLS(ph)PVAAPPLREPR ddPTM_PC-9_AZD4547_30min_R2 2 SLSPVAAPPLREPR 14 1 Q8NDT2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 S(0.003)LS(0.997)PVAAPPLREPR;S(0.259)LS(0.741)PVAAPPLREPR 82.837 0.0041398 67511000.0 135438.0 122001.0 200867.0 232096.0 224591.0 209742.0 181243.0 215270.0 175326.0 193441.0 True False 178504.46671459413 161435.43739041316 198203.37233583393 178589.85304745432 193410.41637285167 196626.7995833599 197373.27588578506 182004.96791248268 184593.37442487717 186668.68946885786 0.9562635663351257 0.8648233286994047 1.0617922743219366 0.9567209881614809 1.0361160027596301 1.0533464403850297 1.0573453772423524 0.9750160481136648 0.9888823613114458 1.0 17.510120434479887 -5.261628622302458 24.999986617717827 1.0166501193665285 0.9105434460546694 0.5276482026970342 0.039966604084785855 12.233820596011086 1616414.222468829 0.010306756649820609 0.02394660679091724 5.474839320290909e-06 5.261628622302458 -0.10610667331185908 SLS(ph)PVAAPPLREPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLSPVAAPPLREPR 14 1 Q8NDT2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 S(0.067)LS(0.933)PVAAPPLREPR;S(0.234)LS(0.766)PVAAPPLREPR;S(0.094)LS(0.906)PVAAPPLREPR;S(0.45)LS(0.55)PVAAPPLREPR 74.33800000000001 0.0088588 65334500.0 138949.0 125990.0 166827.0 183922.0 200411.0 174654.0 178390.0 170991.0 155752.0 142933.0 True False 162470.32133215494 138497.45456109737 170804.78837492105 173617.4466231697 161141.90321240114 165494.83677920516 161491.6077682431 166502.6674299402 158029.57834616507 168845.6214429944 0.9622418392828038 0.8202608594612377 1.0116033031545808 1.028261468312854 0.9543741900751973 0.9801547435156882 0.9564453397612436 0.9861236910200527 0.9359412284168647 1.0 17.365345241852182 -5.2782430943034795 24.998575015232042 0.9808596912699462 0.891251337477236 0.4347332774476176 0.04120821736856165 623.4201674812642 927449.9813872823 0.010331007486906681 0.021593173917154602 5.2693482955470885e-06 5.2782430943034795 -0.08960835379271026 SLS(ph)PVAAPPLREPR ddPTM_PC-9_Lapatinib_30min_R1 2 SLSPVAAPPLREPR 14 1 Q8NDT2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 S(0.455)LS(0.545)PVAAPPLREPR;S(0.44)LS(0.56)PVAAPPLREPR 68.46300000000001 0.015077000000000002 65630000.0 101776.0 83471.0 99003.0 88502.0 94985.0 83697.0 76523.0 61813.0 90497.0 66650.0 True False 100324.65557656725 83277.72802794313 90863.35550263172 95010.73231401728 89398.16904769496 80117.4744172364 80484.98651008544 64685.05763945081 80304.27488434273 78170.36369445724 1.2834103723593253 1.065336325585601 1.1623760106552312 1.2154316268168281 1.1436325075462563 1.0249085539679692 1.0296099788492135 0.8274882523546118 1.0272982123791345 1.0 16.254334129601688 -6.9321426301421685 1.762879077826486 0.9525130506869359 1.17425205146708 0.6370463145503009 0.07359819148035764 0.2219199092908717 1.4058630276281192 0.032329619056134004 0.02593381116783607 1.1691153693863308e-07 6.9321426301421685 0.22173900078014408 SLS(ph)QGSTNATVLDVAQTGGHK ddPTM_PC-9_AZD4547_30min_R2 2 SLSQGSTNATVLDVAQTGGHK 21 0 A0A2R8Y661;H0Y8T6 A0A2R8Y661 RAPGEF2 1 S(0.115)LS(0.466)QGS(0.394)T(0.023)NAT(0.002)VLDVAQTGGHK;S(0.11)LS(0.427)QGS(0.346)T(0.117)NATVLDVAQTGGHK 168.45 8.897799999999999e-09 23028000.0 72741.0 76872.0 118000.0 160190.0 133644.0 124289.0 108752.0 131866.0 112357.0 124431.0 True False 95871.12489320803 101719.37068610794 116435.24290016961 123260.67041082888 115089.8374633598 116517.18918202478 118430.71731945993 111489.13967922816 118295.96163863823 120074.70856384847 0.7984289617678277 0.8471340210000987 0.9696899896138943 1.0265331632704844 0.9584852533884101 0.9703724504154677 0.9863085968389891 0.9284981076589078 0.985186331522392 1.0 16.873572781417295 -5.182767195815032 3.2225615390005515 0.9773889145488776 0.8072231149260463 0.8676011271218735 0.024603339909561546 0.08442049162434162 1.6739860686065249 0.006656788315802739 0.021728302307612135 6.564970882105201e-06 5.182767195815032 -0.1701657996228313 SLS(ph)QGSTNATVLDVAQTGGHK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSQGSTNATVLDVAQTGGHK 21 0 A0A2R8Y661;H0Y8T6 A0A2R8Y661 RAPGEF2 1 S(0.162)LS(0.53)QGS(0.244)T(0.047)NAT(0.016)VLDVAQTGGHK 114.85 2.0346e-06 6732700.0 48416.0 45747.0 39923.0 38366.0 54777.0 45737.0 49474.0 50492.0 45948.0 52178.0 True False 47725.57896159302 45641.075632187276 36640.685047236606 41187.56362522415 51555.12455572558 43780.93512815443 52035.52164185881 52838.04265010837 40772.85238610981 61196.89777718526 0.7798692531010213 0.7458070145706417 0.5987343538334811 0.6730335216531064 0.8424466995604112 0.7154110211200337 0.8502967230678499 0.8634104761729745 0.6662568507077214 1.0 15.901170900524447 -6.259085246441098 24.898178289959795 0.8121291777184151 0.6954909824803678 0.2841561444990791 0.09510617794237805 281.26103516148294 2974714.093280927 0.027997348778611854 0.03442346203797292 5.506995905237195e-07 6.259085246441098 -0.1166381952380473 SLS(ph)QGSTNSNMLDVQGGAHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSQGSTNSNMLDVQGGAHK 20 0 E9PCH4;Q8TEU7;A0A5F9ZHG7;B7Z7Y1;Q8TEU7-2 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 1 S(0.17)LS(0.828)QGS(0.001)T(0.001)NSNMLDVQGGAHK 161.58 3.0812000000000002e-06 4615400.0 7004.8 10633.0 11158.0 12979.0 19976.0 23449.0 23210.0 26634.0 24397.0 18683.0 True False 8190.574288893619 11688.573968951097 11424.049036950644 12251.828708485731 16061.84619891585 22219.293160394715 21011.38077415176 25934.88572105566 24753.759970410596 22070.08000545338 0.37111665598265975 0.5296117624432228 0.5176260817417895 0.5551329540019058 0.727765653543035 1.0067608796571859 0.9520301135727636 1.175115165629092 1.1215981076776385 1.0 14.429804239038369 -6.579443471727215 1.1357415775156134 1.0984375014991774 0.4593264667779533 0.9384688156383894 0.06801300667495874 0.10337460731281384 0.28287101151959126 0.032153758604996995 0.03470975242871233 2.633640719093412e-07 6.579443471727215 -0.6391110347212241 down SLS(ph)QGSTNSNMLDVQGGAHK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSQGSTNSNMLDVQGGAHK 20 0 E9PCH4;Q8TEU7;A0A5F9ZHG7;B7Z7Y1;Q8TEU7-2 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 1 S(0.167)LS(0.669)QGS(0.062)T(0.079)NS(0.023)NMLDVQGGAHK 64.845 0.004647699999999999 2764600.0 20174.0 20805.0 18581.0 14732.0 28194.0 29902.0 26681.0 28252.0 37509.0 24579.0 True False 19886.315060541507 20756.82730075538 17053.341904734196 15815.440424511342 26535.68435153672 28623.16116496651 28062.41162886437 29564.691058996716 33284.341432719426 28827.447400541154 0.689839609599572 0.7200369499370148 0.5915661441607233 0.5486243788693705 0.9205006597649221 0.9929134816296358 0.973461549992719 1.0255743648826057 1.1546059201930798 1.0 14.815155474945591 -6.423266719957339 3.8144351859750047 1.0230920636021814 0.6412684317699411 0.8896239547147152 0.06523319166213205 0.08139069264706283 2.1399185508540874 0.023101070171299566 0.02603052846149336 3.7734037789277194e-07 6.423266719957339 -0.38182363183224033 SLS(ph)QIHEAAVR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSQIHEAAVR 11 0 Q9NZM1-5;Q9NZM1-2;Q9NZM1-6;Q9NZM1;Q9NZM1-3;H0YD14 Q9NZM1-5 MYOF Myoferlin 1 S(0.051)LS(0.949)QIHEAAVR 59.708999999999996 0.037787 3798900.0 26105.0 30970.0 22328.0 17235.0 17647.0 18108.0 11302.0 12357.0 20487.0 9500.8 True False 25732.7379129293 30898.29086779114 20492.278028572462 18502.519394274557 16609.038155336882 17333.56305180969 11887.16225888929 12931.151331446346 18179.538322325927 11143.000620979756 2.3093185388934074 2.7728878350429804 1.8390269125526322 1.6604611292436338 1.4905355137525356 1.5555561415992838 1.0667828768230028 1.1604729974707089 1.6314760216469844 1.0 13.443850157837286 -5.621295008218514 1.046533331834386 1.2847505359546585 2.6549294826695364 0.7938479012590389 0.23889443358339052 0.28237936417668236 0.5504891515198694 0.08679120461729076 0.31809091268219863 2.3916905732664858e-06 5.621295008218514 1.370178946714878 SLS(ph)RPSSLIEQEK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSRPSSLIEQEK 13 1 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7 Q12802-2 AKAP13 A-kinase anchor protein 13 1 S(0.031)LS(0.956)RPS(0.005)S(0.008)LIEQEK 109.35 0.0038436 16565000.0 35009.0 27323.0 24880.0 18235.0 29538.0 25095.0 26913.0 25668.0 28911.0 26350.0 True False 34509.765240135675 27259.735272220114 22834.462439577346 19576.062730176778 27800.632913942383 24021.74534930221 28306.42345367964 26860.628985640942 25654.738733673283 30904.562390832 1.116656007087587 0.8820618434094655 0.7388702726414048 0.6334360112468093 0.899564037256505 0.7772879953941165 0.9159302466640618 0.8691476891324398 0.8301278759178902 1.0 14.915532216149932 -9.433133315809481 10.393544807729034 1.0 0.8442807068296909 0.11821623705233841 0.1202826503546027 78637527.11557616 0.0 0.12051178435527544 0.030127946088818875 3.688643505321941e-10 9.433133315809481 -0.15571929317030908 SLS(ph)SGSNFCSEQK ddPTM_PC-9_AZD4547_30min_R2 2 SLSSGSNFCSEQK 13 0 O95243-3;O95243-5;O95243-2;O95243 O95243-3 MBD4 Methyl-CpG-binding domain protein 4 1 SLS(0.783)S(0.212)GS(0.004)NFCSEQK;S(0.308)LS(0.536)S(0.156)GSNFCSEQK 201.72 1.9235e-07 43001000.0 104813.0 144582.0 158111.0 188201.0 145722.0 131271.0 120286.0 151377.0 117445.0 128567.0 True False 138141.3537541666 191315.30404489062 156014.34483210795 144814.1671264647 125491.01564481508 123062.60361828953 130991.22097514152 127985.16294740493 123652.90293128045 124065.9084627494 1.1134513539280884 1.542045727270298 1.2575118077578178 1.1672357775056708 1.0114866944491328 0.9919131302314116 1.0558196252153462 1.031590100239602 0.9966710796173878 1.0 16.92074721239826 -5.928813791245728 2.181138943216747 1.0170284170742336 1.3366349774576283 0.6325694358078777 0.09940457016011907 0.17873115313416052 1.7235071127459927 0.02937306157004773 0.048498872265193546 1.1781109938854166e-06 5.928813791245728 0.31960656038339463 SLS(ph)SGSNFCSEQK ddPTM_PC-9_Lapatinib_30min_R1 2 SLSSGSNFCSEQK 13 0 O95243-3;O95243-5;O95243-2;O95243 O95243-3 MBD4 Methyl-CpG-binding domain protein 4 1 S(0.007)LS(0.797)S(0.179)GS(0.017)NFCSEQK;S(0.048)LS(0.903)S(0.049)GS(0.001)NFCSEQK 177.39 4.127e-26 14973000.0 24699.5 32078.3 33031.0 25501.6 53829.0 84486.0 113431.0 102893.0 96853.0 92064.0 True False 24347.280600666443 32004.024667234877 30315.31868334724 27377.072734843772 50662.88405188583 80872.73072648514 119303.90215785439 107673.78440936378 85944.39523269553 107977.13973243102 0.22548551166477804 0.2963962996847419 0.2807568227725707 0.25354508188200364 0.46920009344041913 0.7489801167810981 1.104899633880757 0.9971905597442295 0.7959499153771533 1.0 16.72036638047728 -6.762846778894733 2.0556759758722247 0.9741536213761052 0.26923337685947135 0.9430083923256656 0.07924208642234366 0.069177129377204 0.6017640571396802 0.032092467162094476 0.029474249687818595 1.7264468830152758e-07 6.762846778894733 -0.7049202445166338 down SLS(ph)SPGGPSKPK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSSPGGPSKPK 12 1 J3KRY8;Q9BZE9-3;Q9BZE9;Q9BZE9-2;J3QL04;J3QR12;Q9BZE9-4 J3KRY8 ASPSCR1 Tether containing UBX domain for GLUT4 1 S(0.002)LS(0.499)S(0.499)PGGPSKPK 80.014 0.006962 68586000.0 242320.0 227440.0 228460.0 221620.0 250400.0 216140.0 205120.0 231610.0 217600.0 163370.0 True False 238864.47236395432 226913.37665387153 209676.9006811031 237918.67410264752 235671.96430534104 206896.19604694875 215740.10994013184 242371.44613387497 193091.59657041618 191608.28682315798 1.2466291324049608 1.1842565914870784 1.0942997516314172 1.2416930292906958 1.2299674936442127 1.0797873071006607 1.1259435252883712 1.2649319617244326 1.0077413653232399 1.0 17.547800431649442 -8.282479244246113 23.573115738112648 1.003870481103549 1.178615796387044 0.5723801419847943 0.061971323109272496 334.3998701292021 374655.4013701078 0.06022321481647515 0.015637397235089924 5.218200424088784e-09 8.282479244246113 0.17474531528349502 SLS(ph)SPNCFGPQPGGPEMR ddPTM_PC-9_AZD4547_30min_R2 1 SLSSPNCFGPQPGGPEMR 18 0 Q5T0Z8 Q5T0Z8 C6orf132 Uncharacterized protein C6orf132 1 S(0.006)LS(0.497)S(0.497)PNCFGPQPGGPEMR 89.669 0.0098979 0.0 14519.0 12598.0 15153.0 21964.0 18379.0 13959.0 13945.0 21582.0 19684.0 13657.0 True False 19135.739986039338 16670.05713268273 14952.06131920568 16900.539140417266 15827.39309463265 13086.141523319726 15186.077984955415 18246.997805022504 20724.456054317554 13178.87258686728 1.4520012891776544 1.2649076787717342 1.1345478318157034 1.2823964287551137 1.200967153321189 0.9929636573283241 1.1523047882023165 1.3845643991736896 1.5725515151401823 1.0 13.685939336928396 -14.499837443206365 21.5982668541231 0.006288728393640142 1.2423424222000303 0.0 0.17823957771376128 0.0 0.0 0.0 0.04181179747447265 3.1634615249308185e-15 14.499837443206365 1.2360536938063902 SLS(ph)SPNCFGPQPGGPEMR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSSPNCFGPQPGGPEMR 18 0 Q5T0Z8 Q5T0Z8 C6orf132 Uncharacterized protein C6orf132 1 S(0.03)LS(0.796)S(0.174)PNCFGPQPGGPEMR 68.41 0.010579 3884600.0 14603.0 14999.0 13414.0 9478.7 14450.0 13801.0 14732.0 14499.0 14059.0 17085.0 True False 14394.758542137784 14964.27073703581 12311.1526995374 10175.795218016263 13600.079409793056 13210.763401702328 15494.750875770393 15172.676471201798 12475.52737216675 20038.119485668496 0.7183687347723966 0.7467901739850606 0.6143866298602763 0.5078218654846386 0.6787103659861893 0.659281596317001 0.7732637230181417 0.7571906376770274 0.6225897285965082 1.0 14.290459502054624 -7.236325323430255 5.123225210491366 0.7685266135433195 0.6503518932722141 0.27135119007362507 0.10555666080532158 0.3060477748308137 23.487834042726035 0.0424980614665486 0.03137987784649206 5.8032953857773433e-08 7.236325323430255 -0.11817472027110543 SLS(ph)SPPSSK ddPTM_PC-9_AZD4547_30min_R2 3 SLSSPPSSK 9 0 Q5VW31;A0A1B0GWB8;A0A2R8Y7V8;Q5VW30;Q5VW27;A0A1B0GWI9;A0A1B0GU97;A0A0A0MRX8;A0A1B0GWJ4;A0A1B0GVN4;U3KQE8;A0A1B0GW37;Q5VW26;O00712-4;O00712;O00712-5;O00712-6 Q5VW31 NFIB Nuclear factor 1;Nuclear factor 1 B-type 1 S(0.013)LS(0.91)S(0.075)PPS(0.002)SK;SLS(0.5)S(0.5)PPSSK;S(0.001)LS(0.602)S(0.396)PPS(0.001)SK 102.53 0.0031473000000000004 98803900.0 274668.0 264211.0 343979.0 502360.0 399385.0 355904.0 358112.0 473400.0 366409.0 353942.0 True False 362006.71055068827 349612.03882229194 339417.6137081138 386548.6633846304 343937.2866369142 333649.2666176356 389983.27424513205 400246.9076497849 385776.63170120114 341550.5983115594 1.0598918940275694 1.023602478082556 0.9937549967296502 1.131746409742852 1.006987803087312 0.9768662923356489 1.1418023454592012 1.1718524564980655 1.129486036939391 1.0 18.381739793877017 -7.277627928908891 24.958428000670974 1.1251062544797845 1.033392785606692 0.29144603098751964 0.058369373732394834 907.6495043473328 1399348.8958453506 0.023933130846459247 0.016196746235986933 5.276817461521964e-08 7.277627928908891 -0.09171346887309251 SLS(ph)SPPSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSSPPSSK 9 0 Q5VW31;A0A1B0GWB8;A0A2R8Y7V8;Q5VW30;Q5VW27;A0A1B0GWI9;A0A1B0GU97;A0A0A0MRX8;A0A1B0GWJ4;A0A1B0GVN4;U3KQE8;A0A1B0GW37;Q5VW26;O00712-4;O00712;O00712-5;O00712-6 Q5VW31 NFIB Nuclear factor 1;Nuclear factor 1 B-type 1 S(0.062)LS(0.899)S(0.032)PPS(0.006)S(0.001)K;S(0.007)LS(0.977)S(0.017)PPSSK 111.27 0.0022465 33616800.0 174154.0 185011.0 144594.0 177610.0 182200.0 174346.0 193258.0 204442.0 168476.0 156778.0 True False 203634.83250170999 203377.66938489687 148041.66933579894 167659.0875193894 146499.2179336435 165202.98884140817 174951.2031732452 199075.6141242047 170939.64277472204 185200.61034603484 1.0995365086607007 1.0981479434916517 0.7993584311584777 0.9052836662154067 0.7910298873201314 0.8920218380098075 0.9446578110426347 1.0749187799772655 0.922997189130926 1.0 17.49872932758003 -10.370282082759278 18.32395612885949 0.9999345277681272 0.9438023425654497 0.020181103434948278 0.10680317476583136 0.0 0.0 0.11153252828685382 0.02705061145993459 4.263025370240051e-11 10.370282082759278 -0.05613218520267749 SLS(ph)SPPSSK ddPTM_PC-9_Lapatinib_30min_R1 3 SLSSPPSSK 9 0 Q5VW31;A0A1B0GWB8;A0A2R8Y7V8;Q5VW30;Q5VW27;A0A1B0GWI9;A0A1B0GU97;A0A0A0MRX8;A0A1B0GWJ4;A0A1B0GVN4;U3KQE8;A0A1B0GW37;Q5VW26;O00712-4;O00712;O00712-5;O00712-6 Q5VW31 NFIB Nuclear factor 1;Nuclear factor 1 B-type 1 S(0.001)LS(0.979)S(0.02)PPSSK;S(0.074)LS(0.462)S(0.462)PPS(0.001)SK;S(0.002)LS(0.885)S(0.105)PPS(0.007)S(0.001)K 111.27 0.0022465 79869100.0 277858.0 238728.0 228025.0 179558.0 271740.0 224276.0 271098.0 254046.0 259877.0 225798.0 True False 273895.69396708347 238175.2399834042 209277.66470195464 192763.29430792865 255756.78746139567 214684.23829289127 285134.1279472986 265849.9046005201 230606.9156338702 264826.8834430771 1.0342442972786623 0.8993620167515904 0.7902432788585739 0.7278841626717324 0.9657508487667152 0.8106587801877612 1.076681204869393 1.003862980767445 0.8707836328234317 1.0 18.01469005670795 -7.251823872254634 24.756611365188785 0.9881538721407173 0.8667122942327524 0.26661507407098384 0.09444805411125654 836.0911663624648 2152650.052162363 0.037739050180460865 0.028841237722577635 5.599846567362524e-08 7.251823872254634 -0.12144157790796484 SLS(ph)SPTDNLELSLR ddPTM_PC-9_AZD4547_30min_R2 3 SLSSPTDNLELSLR 14 0 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 S(0.054)LS(0.558)S(0.387)PT(0.001)DNLELSLR;S(0.209)LS(0.712)S(0.076)PT(0.003)DNLELSLR;S(0.01)LS(0.495)S(0.495)PTDNLELSLR 178.67 7.0648e-05 44193000.0 94735.0 105074.0 112877.0 164423.0 141542.0 125527.0 110872.0 127760.0 101048.0 125021.0 True False 124858.75938958858 139037.1156659395 111380.17722747843 126517.81766002672 121891.33649276313 117677.77684631823 120739.39321247628 108017.62763273447 106389.19098641931 120644.05284343073 1.0349350543754328 1.1524572690406785 0.92321315972388 1.048686733230181 1.010338542347803 0.9754129944477075 1.0007902616564885 0.8953415032642963 0.8818436423425606 1.0 16.880397273995776 -6.214792126570597 0.5335739436519505 0.9278728183596904 1.086443143824723 0.3494483735036932 0.06130129985621228 1.305774985165741 0.7283188203104544 0.04775518577937277 0.10779105160010893 6.098287196305034e-07 6.214792126570597 0.1585703254650327 SLS(ph)SPTDNLELSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSSPTDNLELSLR 14 0 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 SLS(0.598)S(0.399)PT(0.002)DNLELSLR;SLS(0.668)S(0.332)PTDNLELSLR 209.53 4.3579e-11 24199000.0 67608.0 67953.0 70271.0 79281.0 92869.0 85216.0 84720.0 77197.0 77033.0 61238.0 True False 79052.69908113305 74698.92475426829 71946.52714425148 74839.14260247002 74671.98611569456 80747.1229458056 76694.70828031625 75170.66054698257 78159.46189288187 72339.96464025874 1.0927942731829665 1.0326093622763086 0.994561270551295 1.0345476801742923 1.032236972841123 1.1162173405441245 1.0601983103214567 1.039130457428348 1.0804465039700124 1.0 16.14250527235464 SLS(ph)SPTDNLELSLR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSSPTDNLELSLR 14 0 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 S(0.019)LS(0.604)S(0.37)PT(0.006)DNLELSLR 178.68 7.041899999999999e-05 10531000.0 35589.0 30572.0 29828.0 29612.0 36796.0 27459.0 30258.0 27828.0 30616.0 26761.0 True False 35081.49433377673 30501.21241233809 27375.656979409676 31789.76526273622 34631.73162371942 26284.64258005536 31824.611186468945 29120.990471108624 27167.70367922735 31386.603193208928 1.1177219184192337 0.9717908059237704 0.8722083371332424 1.0128450366879624 1.1033921514390774 0.8374478250562178 1.013955253155741 0.927815931269985 0.8655827937795315 1.0 14.937861281630246 -6.764232456069257 24.999999999684615 0.9297610574977863 1.0050399313438179 0.21656740839282562 0.08114654326006361 141.37439450467724 1265389.7576532157 0.028606054237129138 0.02635224544771595 1.7209471916452926e-07 6.764232456069257 0.0752788738460316 SLS(ph)SPTVTLSAPLEGAK ddPTM_PC-9_AZD4547_30min_R2 1 SLSSPTVTLSAPLEGAK 17 0 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 S(0.186)LS(0.627)S(0.186)PT(0.001)VTLSAPLEGAK 186.96 2.5611999999999998e-08 405770000.0 145870.0 113780.0 173500.0 188250.0 187590.0 159250.0 138940.0 161440.0 137720.0 162140.0 True False 192253.62571551482 150557.1599108302 171199.27663711383 144851.87093350737 161546.36653910106 149292.072325286 151305.3908375549 136493.15752214074 144999.5980390474 156463.52795157477 1.2287440289280518 0.9622508317556755 1.0941800870685963 0.9257868132587347 1.03248577258912 0.954165320696921 0.9670329745113744 0.8723640538412579 0.9267309764606905 1.0 17.255466874881492 -1.5228787452803376 0.6996925311506841 0.9505079360036457 31.536757708473967 0.6007217147170307 0.06122995311719801 196.42823395294465 1.0436000632634435 0.023399825549159033 9398.571195931865 0.029999999999999995 1.5228787452803376 30.58624977247032 SLS(ph)SPTVTLSAPLEGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSSPTVTLSAPLEGAK 17 0 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 SLS(0.76)S(0.24)PTVTLSAPLEGAK;S(0.057)LS(0.732)S(0.205)PT(0.006)VTLSAPLEGAK 278.89 6.316599999999999e-83 335860000.0 254094.0 212353.0 254966.0 231910.0 290574.0 231672.0 239974.0 248990.0 260797.0 180176.0 True False 297107.0956147399 233434.00244791392 261045.35640393922 218916.83456236424 233638.11060291206 219522.71248475238 217241.9254586937 242454.2763267114 264610.66274554963 212840.48252756827 1.3959144054104322 1.096755653228132 1.226483577296566 1.0285488548167003 1.097714625659383 1.0313954839691672 1.0206795383982243 1.1391360959506724 1.24323464973951 1.0 17.699413053787012 -2.1759916856712165 1.203514746208679 1.0907251264544917 199.9994059021416 0.5413270354592523 0.08124175685037666 802.7736232370287 2.3371171187366357 0.02401087016749511 439449.84877029556 0.0066681953498434815 2.1759916856712165 198.90868077568712 SLS(ph)SPTVTLSAPLEGAK ddPTM_PC-9_Lapatinib_30min_R1 3 SLSSPTVTLSAPLEGAK 17 0 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 S(0.241)LS(0.587)S(0.152)PT(0.017)VT(0.001)LS(0.002)APLEGAK;SLS(0.5)S(0.5)PTVTLSAPLEGAK;S(0.061)LS(0.467)S(0.467)PT(0.001)VT(0.001)LS(0.003)APLEGAK 298.1 3.344599999999999e-112 338956100.0 177655.0 146862.0 162213.0 126799.0 134433.0 130714.0 114975.1 103947.8 163380.0 113419.0 True False 175121.60712206343 146521.9500621741 148876.4733002876 136124.22144906427 126525.91524544706 125123.6669292165 120927.94810051503 108777.59426810066 144978.42393232824 133023.32302868212 1.3164729547787961 1.1014756414601177 1.1191757197960486 1.023310937885032 0.9511558752608059 0.9406145033847763 0.9090732763790669 0.8177332500154603 1.089872216626767 1.0 17.02131969059851 -4.389143709982073 0.6161962115052664 0.9336739627434875 1.7186877502928346 0.6975271466813162 0.07243136266256461 2.898277167063437 0.5895463160963819 0.033718705193515254 1.7918976729664113 4.081842939782198e-05 4.389143709982073 0.7850137875493471 SLS(ph)SSLDDTEVKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSSSLDDTEVKK 13 1 O95292 O95292 VAPB Vesicle-associated membrane protein-associated protein B/C 1 S(0.003)LS(0.709)S(0.125)S(0.163)LDDTEVKK 74.649 0.032478 0.0 14816.0 10603.0 14999.0 18358.0 20777.0 19576.0 16072.0 21332.0 15633.0 13419.0 True False 17324.056170661228 11655.595767214187 15356.633044024258 17329.46077743903 16705.89599894247 18549.400098421538 14549.5438087965 20772.057603122306 15861.603050269663 15851.758475254452 1.0928791400465205 0.7352872418166901 0.9687652677775078 1.09322008687499 1.0538828247365348 1.1701793291500289 0.9178504600299842 1.3103945303953968 1.0006210399326094 1.0 13.952355270564553 -5.632723935106321 4.285606984011049 1.0868504093018532 0.9008618853090293 0.2129332671151778 0.12903722414811267 0.26454751512262603 8.566416523864163 0.03326737258470239 0.059928604155498465 2.329571609378496e-06 5.632723935106321 -0.18598852399282384 SLS(ph)SSLDDTEVKK ddPTM_PC-9_Lapatinib_30min_R1 2 SLSSSLDDTEVKK 13 1 O95292 O95292 VAPB Vesicle-associated membrane protein-associated protein B/C 1 S(0.022)LS(0.87)S(0.059)S(0.049)LDDTEVKK;S(0.001)LS(0.985)S(0.013)S(0.002)LDDTEVKK 198.29 1.0422e-06 9350100.0 93753.0 86240.0 41771.0 25450.7 37239.0 62201.0 56439.0 48211.0 65925.0 24452.0 True False 92416.0650278056 86040.31657856978 38336.74962072286 27322.429379046356 35048.67523469089 59540.80822761295 59361.13526185208 50451.05906290846 58499.83227897377 28678.495619758025 3.2224865018420155 3.0001684090881104 1.3367768703429057 0.9527148753305802 1.2221239112188345 2.076148240725443 2.0698831643370887 1.7591947545585427 2.0398501042247963 1.0 14.807681726502839 -5.2312517418194115 7.659968523337966 1.587460709608156 3.1216467038409856 0.6974305275847719 0.4091381892302735 0.14963032701571016 32.0849684976393 0.11529133851800434 0.29966713227697517 5.871489089170565e-06 5.2312517418194115 1.5341859942328295 SLS(ph)SSPVKK ddPTM_PC-9_AZD4547_30min_R2 1 SLSSSPVKK 9 1 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 SLS(0.496)S(0.327)S(0.177)PVKK 96.171 0.0023794000000000003 167690000.0 1075100.0 753480.0 927320.0 1155700.0 1053000.0 863450.0 771060.0 793330.0 724130.0 871490.0 True False 1416959.4365308103 997027.6748955206 915023.1308998766 889271.2203870082 906809.1261030611 809458.335003254 839682.846258853 670739.0774098105 762406.0334593044 840979.4003609098 1.6848919675353717 1.1855554065505554 1.0880446423624535 1.0574233090672303 1.0782774533049209 0.9625186237092985 0.9984582807836906 0.7975689738915841 0.9065692133863382 1.0 19.681710936794595 -1.5228787452808688 0.6778619898998626 0.9448209440505669 77.75092932991937 0.8988032095893129 0.07213166577625867 78.03987287696873 0.4522534607945791 0.03135333398355122 9047.752047312795 0.029999999999963306 1.5228787452808688 76.80610838586881 SLS(ph)SSPVKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSSSPVKK 9 1 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 S(0.004)LS(0.472)S(0.472)S(0.052)PVKK 64.10300000000001 0.02509 119510000.0 257830.0 229980.0 207810.0 269110.0 300080.0 285970.0 318260.0 286520.0 267730.0 220400.0 True False 301475.5266253773 252810.8945151291 212764.97852381342 254032.63916639137 241281.47814230373 270973.22977858625 288112.1087971357 278999.153593034 271645.0447546025 260356.77531456013 1.1579323267510053 0.971017152173919 0.8172054607250115 0.9757097308471115 0.9267340089413466 1.0407765630496824 1.1066049978881551 1.0716032000932196 1.0433569259966597 1.0 17.99013042518468 -6.886859166053531 5.687171285583939 1.0628959591493752 0.9620280113171152 0.19883026573661933 0.0820149110190481 0.31532628590912715 14.538209973815322 0.03028797739199116 0.026702105008388224 1.297599991273695e-07 6.886859166053531 -0.10086794783225994 SLS(ph)SSPVKK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSSSPVKK 9 1 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 SLS(0.333)S(0.333)S(0.333)PVKK 123.51 0.0021909000000000004 29237000.0 196650.0 157590.0 171520.0 142290.0 175690.0 169870.0 152800.0 179530.0 205150.0 167320.0 True False 193845.73493880706 157225.11003730062 157418.287686347 152754.4812655253 165356.2596198301 162605.05608631085 160711.23634385795 187871.61920648697 182043.84667472861 196241.03906011407 0.9877940713482807 0.8011836402330617 0.802168029889637 0.7784023260228069 0.842618141504932 0.8285986298538728 0.8189481523007409 0.9573513272569694 0.9276543150536598 1.0 17.58226725226939 -7.764953061304361 24.992311771651362 0.9568771595223344 0.8320042151529702 0.5026613035579363 0.05656168644164128 75.44368650597421 536602.3824516676 0.02920880521217762 0.014910750330230682 1.7180940693157585e-08 7.764953061304361 -0.12487294436936425 SLS(ph)TDTSRQESDTVSYKPPDSK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSTDTSRQESDTVSYKPPDSK 22 2 A0A087WVA8;Q8IWB9;Q8IWB9-2 A0A087WVA8 TEX2 Testis-expressed sequence 2 protein 1 S(0.157)LS(0.64)T(0.157)DT(0.034)S(0.01)RQES(0.001)DTVSYKPPDSK 89.29700000000001 0.00072215 0.0 19712.0 11217.0 11049.0 7418.6 7567.9 9028.6 6696.1 4376.7 10751.0 7832.3 True False 19430.90326526193 11191.027725670432 10140.593870373397 7964.18859172413 7122.771001063869 8642.467824694559 7042.791293731069 4580.057459928885 9540.109166951039 9186.102619116258 2.11524996736116 1.218256336738709 1.1039060078940164 0.8669823234012944 0.775385524895117 0.9408198648586402 0.766678926389853 0.4985854883003153 1.0385371862816004 1.0 13.16523718484006 -1.841751946728932 0.8143064798907076 0.8078511600258597 199.99999999998394 0.8611555604348659 0.15230381106761456 96.61100947916907 0.567583916897059 0.05220932383249996 35197.75034581073 0.014396206026006823 1.841751946728932 199.1921488399581 up SLS(ph)TEVEPK ddPTM_PC-9_AZD4547_30min_R2 1 SLSTEVEPK 9 0 A0A087WVA8;Q8IWB9;Q8IWB9-2 A0A087WVA8 TEX2 Testis-expressed sequence 2 protein 1 S(0.008)LS(0.981)T(0.011)EVEPK 133.07 0.0011812 7765700.0 42775.0 39895.0 52613.0 72332.0 66584.0 61133.0 48556.0 69751.0 55058.0 49010.0 True False 56376.56022472847 52790.27856075386 51915.31724327649 55656.974918260006 57339.960923500774 57310.34384591336 52877.38993456402 58972.585668525935 57968.25347686528 47294.17481748297 1.1920402553231157 1.1162110083214556 1.097710604818191 1.1768251615140901 1.2124106434838193 1.2117844125007922 1.118052913252588 1.2469312742237735 1.2256954202198382 1.0 15.529374878558883 -5.895127916015916 8.881324027150738 1.1822777275234988 1.1335436863259263 0.03024312645177607 0.0708533293212963 0.6639779638305028 51.271458072835486 0.019019767525571694 0.02827409952817152 1.2731280418226813e-06 5.895127916015916 -0.04873404119757252 SLS(ph)TEVEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSTEVEPK 9 0 A0A087WVA8;Q8IWB9;Q8IWB9-2 A0A087WVA8 TEX2 Testis-expressed sequence 2 protein 1 S(0.004)LS(0.983)T(0.013)EVEPK;SLS(0.967)T(0.033)EVEPK 127.83 0.0013495999999999998 20929600.0 79792.0 94948.0 69236.0 91406.0 104505.0 87397.0 74033.0 80899.0 67227.0 65299.0 True False 93299.20963616387 104373.80995052832 70886.84881899212 86284.81816225048 84027.9954454197 82813.74746637457 67020.05828749583 78775.48696957585 68210.0676940112 77137.1917934005 1.2095230260138419 1.3530932034715069 0.918971084776473 1.1185890509645517 1.0893317930276112 1.0735903854029039 0.8688423408904776 1.0212387194566697 0.88426952172048 1.0 16.23513900465172 -4.206013804286839 0.39916097619279556 0.9469821579006608 1.7109508008318042 0.484006946830698 0.10278880989194229 7.4821498734272796 0.6618513705701016 0.08035323891597258 2.9895788584711114 6.222805053297403e-05 4.206013804286839 0.7639686429311434 SLS(ph)TEVEPK ddPTM_PC-9_Lapatinib_30min_R1 2 SLSTEVEPK 9 0 A0A087WVA8;Q8IWB9;Q8IWB9-2 A0A087WVA8 TEX2 Testis-expressed sequence 2 protein 1 S(0.001)LS(0.97)T(0.029)EVEPK;SLS(0.975)T(0.024)EVEPK 112.13 0.002189 28560000.0 238880.0 256060.0 152436.0 192317.0 164737.0 186865.0 163552.0 166043.0 194383.0 243580.0 True False 235473.52739477335 255467.10880227917 139903.3004999764 206460.63373070498 155047.4935454035 178873.21955359058 172019.9222939178 173757.96394977288 172489.5395962651 285682.47845005116 0.8242491057635641 0.8942344318359907 0.4897160695994072 0.7226926721262069 0.542726646683416 0.6261259721774111 0.6021367611594487 0.6082205842391304 0.6037806047192469 1.0 18.12405302968768 -10.660712106138375 4.939381331336154 1.0000169982308917 0.6537500495162805 0.4322114490459382 0.11784990152227943 2.5710818163300258e-05 4.487881582276375e-06 0.11841619473350401 0.028718563758542315 2.1841773234423588e-11 10.660712106138375 -0.3462669487146113 SLS(ph)TSGESLYHVLGLDK ddPTM_PC-9_AZD4547_30min_R2 1 SLSTSGESLYHVLGLDK 17 0 Q9H3Z4-2;Q9H3Z4 Q9H3Z4-2 DNAJC5 DnaJ homolog subfamily C member 5 1 S(0.196)LS(0.754)T(0.03)S(0.008)GES(0.012)LYHVLGLDK 101.23 0.00061333 2030500.0 8738.3 9016.2 25465.0 29788.0 27158.0 18533.0 21296.0 32891.0 15530.0 20792.0 True False 11516.897632068834 11930.5103285993 25127.317461464576 22920.836820012293 23387.580481203193 17374.128580248187 23191.302744181463 27808.451709989604 16350.884094876623 20064.07840859225 0.5740058126535647 0.5946203999825964 1.2523534323263033 1.1423817408028403 1.165644392178396 0.8659320516215627 1.1558618478210296 1.38598200942441 0.8149332235401608 1.0 14.292327270733965 -5.250661331860682 24.211711119828486 1.1094667168510066 0.5843129421426518 0.6167938931507846 0.16171695720855242 286.3001264537869 643136.8393161799 0.04031682023935815 0.1042187001220323 5.6148565872702674e-06 5.250661331860682 -0.5251537747083548 SLS(ph)TSGESLYHVLGLDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSTSGESLYHVLGLDK 17 0 Q9H3Z4-2;Q9H3Z4 Q9H3Z4-2 DNAJC5 DnaJ homolog subfamily C member 5 1 S(0.209)LS(0.776)T(0.01)S(0.003)GES(0.002)LYHVLGLDK;S(0.007)LS(0.935)T(0.026)S(0.026)GES(0.006)LYHVLGLDK 147.49 4.5852e-05 325780000.0 417790.0 540680.0 1009310.0 850610.0 1755860.0 934790.0 869270.0 773180.0 833060.0 537260.0 True False 488513.595271367 594355.1371703636 1033375.7782294889 802953.0794148287 1411811.8375464745 885767.966796254 786926.4526301982 752884.8442519268 845241.9265053174 634660.985052181 0.7697236899337716 0.9364923182122129 1.6282327141072428 1.2651684888883015 2.2245133556309553 1.3956552989048594 1.2399162248259175 1.1862787566656954 1.3318006721900872 1.0 19.27562663200665 -3.555035252026253 10.913091003535051 1.3280444920921493 1.2404959808278053 0.0 0.3876623067582626 0.0 0.0 0.0927685464127982 0.0 0.00027858950261512713 3.555035252026253 -0.08754851126434393 SLS(ph)TSGESLYHVLGLDK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSTSGESLYHVLGLDK 17 0 Q9H3Z4-2;Q9H3Z4 Q9H3Z4-2 DNAJC5 DnaJ homolog subfamily C member 5 1 SLS(0.333)T(0.333)S(0.333)GES(0.001)LYHVLGLDK 227.41 4.2657999999999997e-29 14927000.0 38696.0 46201.0 65859.0 36271.0 54079.0 53784.0 32490.0 35850.0 77262.0 30763.0 True False 38144.18794402269 46094.024423080984 60444.32724309187 38938.49033650901 50898.17954340472 51483.78369662763 34172.17322520908 37515.7218768594 68559.93995507131 36080.343560879126 1.057201350637396 1.2775384010771837 1.6752702795388543 1.0792161740590764 1.4106899912835682 1.4269205505141034 0.9471132991721559 1.0397828339289046 1.9002019711754872 1.0 15.138925455704182 SLS(ph)VEHLETK ddPTM_PC-9_AZD4547_30min_R2 2 SLSVEHLETK 10 0 J3KN34;P26045-2;P26045 J3KN34 PTPN3 Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 3 1 S(0.027)LS(0.973)VEHLETK;S(0.005)LS(0.994)VEHLET(0.001)K 84.352 0.012598999999999999 19155900.0 145278.0 155040.0 197803.0 288571.0 262994.0 223193.0 197346.0 256700.0 208542.0 232293.0 True False 191473.38202987943 205153.64802755442 195180.00297781598 222045.41432750627 226481.82270688386 209236.70642698568 214909.41169014055 217032.91337917172 219565.10437306872 224160.49277448622 0.854179876480325 0.9152087662206676 0.870715443930498 0.9905644459431672 1.0103556603738062 0.9334236547984643 0.9587301001624198 0.968203231055148 0.9794995614769609 1.0 17.774172506814104 -5.760288800115072 24.999999999999932 0.9747101135910894 0.8835520871980286 0.7607440477021454 0.024932731919461864 15.396601969904 334523.5031463516 0.007011941007535478 0.01132751908810222 1.7366455982171505e-06 5.760288800115072 -0.09115802639306081 SLS(ph)VEHLETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSVEHLETK 10 0 J3KN34;P26045-2;P26045 J3KN34 PTPN3 Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 3 1 S(0.012)LS(0.988)VEHLETK;S(0.44)LS(0.56)VEHLETK 66.393 0.039337000000000004 11855500.0 86629.0 89883.0 98865.0 100758.0 109832.0 96404.0 108142.0 77498.0 89882.0 79261.0 True False 101293.5786992583 98805.99022394734 101222.31654760022 95112.85592184331 88311.2080356088 91348.40453045728 97898.00687972075 75463.75961591829 91196.35420996227 93630.39187026913 1.081845079102168 1.0552769058240121 1.0810839784570183 1.0158331501338607 0.943189559197505 0.9756277070486505 1.0455793778516347 0.8059750483633362 0.9740037651056788 1.0 16.514689275636357 -6.025670137039538 2.8432913456826543 0.9529001374968565 1.0711101929967721 0.4385455946076682 0.058403926246388314 0.2530312652822444 4.115449476620826 0.018137629316730495 0.02653293627380941 9.426052687812549e-07 6.025670137039538 0.11821005549991559 SLS(ph)VEHLETK ddPTM_PC-9_Lapatinib_30min_R1 2 SLSVEHLETK 10 0 J3KN34;P26045-2;P26045 J3KN34 PTPN3 Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 3 1 S(0.431)LS(0.569)VEHLETK;S(0.005)LS(0.987)VEHLET(0.008)K 101.89 0.0034281999999999997 19841700.0 234935.0 202326.0 208562.0 176416.0 207694.0 196543.0 177789.0 179628.0 202306.0 150228.0 True False 231584.78381819787 201857.52657787217 191414.83743260152 189390.22114652384 195477.84726211466 188137.3140541106 186994.0444917418 187974.17264425347 179520.167903376 176194.70963377284 1.3143685431847263 1.1456503262637137 1.0863824335615087 1.0748916442507175 1.1094422055487507 1.0677807208012142 1.0612920494628686 1.066854805317167 1.018873769118921 1.0 17.426811081443702 -1.52287875798741 0.7937915573752996 1.0565400836920487 62.656055962547214 0.8924658177150182 0.02721229786972965 144.13110215176232 0.5152117245941633 0.009747227341926882 15955.735355236948 0.02999999912222655 1.52287875798741 61.599515878855165 SLS(ph)VPAASTAKPPPLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSVPAASTAKPPPLPR 17 1 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7 P49815 TSC2 Tuberin 1 S(0.019)LS(0.981)VPAASTAKPPPLPR 98.804 0.00062278 6158500.0 26424.0 25113.0 24483.0 20886.0 21532.0 22701.0 24255.0 25698.0 19977.0 20364.0 True False 30897.06130221062 27606.052673964892 25066.76757229455 19715.82513332562 17312.959168755307 21510.519597173472 21957.390809006913 25023.454729281675 20269.12583222907 24055.831998664686 1.284389635907238 1.147582535307749 1.0420245524530591 0.8195860835085655 0.7196990388740797 0.8941914625263221 0.912767881411283 1.0402240392546265 0.8425867720290942 1.0 14.554099077102617 -5.3147483322512095 2.0474367470550012 0.8872703993581773 1.255895933739703 0.6828463607260041 0.08938636457598582 0.21548348509451914 1.664741625438117 0.027146340022707945 0.09581169698191894 4.844530201989735e-06 5.3147483322512095 0.3686255343815258 SLS(ph)VPDSGR ddPTM_PC-9_AZD4547_30min_R2 2 SLSVPDSGR 9 0 O75420 O75420 GIGYF1 PERQ amino acid-rich with GYF domain-containing protein 1 1 SLS(1)VPDSGR;S(0.32)LS(0.68)VPDSGR 146.11 0.00045592 38370000.0 197161.0 183777.0 260200.0 341300.0 274820.0 260180.0 240870.0 362830.0 267820.0 255130.0 True False 259854.09679643894 243179.3212948908 256749.5779883401 262618.5580324359 236665.98673850278 243910.9034699705 262306.9633729801 306762.9605039527 281976.4184346332 246197.97635552872 1.055468045038639 0.9877389119710767 1.0428581980607918 1.0666966557564006 0.9612832332818974 0.9907104318263953 1.0654310293525273 1.2460011452773418 1.1453238674368211 1.0 17.90945937795763 -7.532679114819034 24.737543459839 1.1485407698060588 1.0178743651749926 0.3763002117452853 0.0639084558530777 160.84682784864438 405994.0448742544 0.028745721756333286 0.01662144874413978 2.9330595811775402e-08 7.532679114819034 -0.13066640463106616 SLS(ph)VPDSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLSVPDSGR 9 0 O75420 O75420 GIGYF1 PERQ amino acid-rich with GYF domain-containing protein 1 1 S(0.003)LS(0.997)VPDSGR;SLS(1)VPDSGR;S(0.001)LS(0.999)VPDSGR 150.15 0.00023091 36890600.0 270894.0 234993.0 233452.0 274046.0 321747.0 276591.0 316208.0 320984.0 306161.0 280510.0 True False 316751.0037996154 258321.55202536684 239018.38105164052 258692.09108911906 258702.98503016515 262086.08104937247 286254.48909232987 312558.51011065976 310638.0254252936 331364.2424840625 0.9558997718797316 0.7795697872796014 0.7213161542713423 0.7806880101179332 0.7807208861487458 0.7909304850899171 0.8638665625066583 0.9432475506939852 0.9374518599128396 1.0 18.33805840417118 -7.6421278275036215 1.8244221724395828 0.9677351836166991 0.7940835286936174 0.5969208742644304 0.05838686335269246 0.25517544796850095 1.6642970894952291 0.040780369484124994 0.018267603178440908 2.279670989237247e-08 7.6421278275036215 -0.17365165492308166 SLS(ph)VPDSGR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSVPDSGR 9 0 O75420 O75420 GIGYF1 PERQ amino acid-rich with GYF domain-containing protein 1 1 SLS(1)VPDSGR 123.51 0.0014914000000000001 19894000.0 96210.0 103240.0 92468.0 87867.0 109890.0 91868.0 117580.0 125890.0 120500.0 120410.0 True False 94838.02775724661 103000.9541230465 84865.63797680204 94329.03229571941 103426.48625205248 87939.01979476772 123667.71707664157 131739.30898404008 106928.02107874617 141222.70806376025 0.6715494204687568 0.7293512179113778 0.6009347869075439 0.667945216382135 0.7323644169559242 0.6226974471772937 0.8756928596837781 0.9328479165302613 0.7571588347567272 1.0 17.107612561466077 -7.272201157382815 23.546049984659845 0.8858289478292193 0.6729601454174208 0.715642284815356 0.06808414285639344 179.95245720690002 393721.17657231406 0.026887501543911268 0.018360114324657843 5.3431681614587366e-08 7.272201157382815 -0.2128688024117985 SLS(ph)VPVDLSR ddPTM_PC-9_AZD4547_30min_R2 3 SLSVPVDLSR 10 0 Q9NYF3;D6RHW3 Q9NYF3 FAM53C Protein FAM53C 1 S(0.006)LS(0.994)VPVDLSR;S(0.092)LS(0.908)VPVDLSR;S(0.009)LS(0.991)VPVDLSR 151.79 0.00011643 175353000.0 183198.0 159756.0 251049.0 328265.0 243035.0 223172.0 211858.0 283319.0 214308.0 224534.0 True False 241451.1532448808 211394.00280114776 247719.92622749764 252588.57589369314 209293.78533946615 209217.01956030607 230712.9515766716 239538.5585729388 225635.88336154647 216673.1330028306 1.1143566804922072 0.9756355108336672 1.1432886154106676 1.165758635568321 0.9659424887567022 0.9655881957343224 1.0647972287992788 1.1055295839092771 1.0413653055849743 1.0 17.725160747911715 -4.447976517143259 21.019357523853706 1.052488604834209 3.4363985514729514 0.07350291957053634 0.06918575016652387 740.8519480285421 215055.04355614012 0.017548398025516436 2864.8375534636516 3.564704077149032e-05 4.447976517143259 2.3839099466387426 SLS(ph)VPVDLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLSVPVDLSR 10 0 Q9NYF3;D6RHW3 Q9NYF3 FAM53C Protein FAM53C 1 S(0.001)LS(0.999)VPVDLSR;S(0.005)LS(0.99)VPVDLS(0.006)R;S(0.098)LS(0.89)VPVDLS(0.013)R;S(0.293)LS(0.707)VPVDLSR 139.31 0.00012086 90872600.0 132894.0 153821.0 157470.0 163985.0 181004.0 147189.0 149751.0 154468.0 148610.0 125888.0 True False 155390.32942385646 169091.332312426 161224.6820083004 154797.45209654325 145537.5655480861 139470.14972857418 135565.50117664825 150413.3786723745 150783.1401075014 148710.49787114013 1.0449183591497655 1.1370504082297281 1.084151316257471 1.0409315704845366 0.9786636964540094 0.9378635114881206 0.9116068005778434 1.011450979087636 1.0139374305515219 1.0 17.182146969117326 -6.049613724161811 2.3465103971081147 0.9704808457728568 1.094042020156276 0.6620251361116392 0.036507041760966474 0.18054505219926098 1.9745676546914872 0.012261605330490446 0.018159905664276513 8.92043998752491e-07 6.049613724161811 0.12356117438341918 SLS(ph)VPVDLSR ddPTM_PC-9_Lapatinib_30min_R1 3 SLSVPVDLSR 10 0 Q9NYF3;D6RHW3 Q9NYF3 FAM53C Protein FAM53C 1 S(0.062)LS(0.938)VPVDLSR;S(0.005)LS(0.995)VPVDLSR;S(0.005)LS(0.994)VPVDLS(0.001)R 145.23 0.00013692 89496000.0 203175.0 193922.0 222327.0 192227.0 199677.0 196807.0 173378.0 164243.0 195638.0 149654.0 True False 200277.68724226797 193472.9855235319 204048.13226703834 206364.0148304739 187932.39144008618 188390.02338952478 182354.66449493048 171874.3293785505 173603.18828052926 175521.49449857956 1.1410436528837142 1.1022751719168937 1.1625250391694313 1.1757193352301587 1.0707087013870376 1.0733159715150977 1.0389306735102248 0.9792209772914247 0.9890708187989715 1.0 17.421288189340864 -7.024614631841874 1.1003729677468737 0.9873852523021307 1.1419728558506657 0.8627275794196411 0.02523390430792959 0.1810451788110876 0.44865899248249064 0.01641523358868968 0.011512605344456322 9.448989538497459e-08 7.024614631841874 0.15458760354853496 SLS(ph)YEEPR ddPTM_PC-9_AZD4547_30min_R2 2 SLSYEEPR 8 0 Q8IZD4;Q8IZD4-2;F5GZK9 Q8IZD4 DCP1B mRNA-decapping enzyme 1B 1 S(0.047)LS(0.953)YEEPR;S(0.02)LS(0.98)YEEPR 123.86 0.0032984999999999998 47136000.0 113512.0 128890.0 157817.0 216763.0 183329.0 149035.0 136693.0 210464.0 146121.0 156140.0 True False 149606.45480372614 170551.17191867557 155724.24346420402 166791.63930496588 157876.93283888738 139715.81789010356 148858.41219057102 177941.624781589 153844.65774806598 150673.5861253173 0.9929175952532011 1.1319248204315375 1.0335205225332993 1.1069733162536066 1.047807627725665 0.9272747897159626 0.9879529386574992 1.1809742461003916 1.0210459690002418 1.0 17.201067001485264 -4.415872387075972 11.548095587161384 1.0506451332949927 7.284780797851126e-05 0.05254413805928004 0.07046833158494405 283761.97500766406 733960.5926967156 0.018026923126407062 7312040.092178982 3.83820010448752e-05 4.415872387075972 -1.050572285487014 SLS(ph)YEEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLSYEEPR 8 0 Q8IZD4;Q8IZD4-2;F5GZK9 Q8IZD4 DCP1B mRNA-decapping enzyme 1B 1 S(0.033)LS(0.964)Y(0.002)EEPR;S(0.05)LS(0.944)Y(0.006)EEPR;S(0.222)LS(0.769)Y(0.009)EEPR 102.06 0.0043946 64342000.0 105515.0 104971.0 121244.0 126505.0 150339.0 127913.0 132092.0 128509.0 114718.0 109002.0 True False 123376.60548375516 115391.82715082917 124134.9167804303 119417.33498474391 120881.15216754182 121205.0171020328 119579.28949673648 125135.77491654066 116395.53372486647 128763.19974064249 0.9581666635518757 0.8961553253045418 0.9640558562575753 0.9274182004274263 0.9387864887718164 0.9413016867099175 0.9286759706002613 0.9718287147926716 0.9039503053614136 1.0 16.974360807503594 -11.886625085085484 2.3954706152051974 1.4682267816462686 0.9370364670160389 0.4031497838026066 0.02310120965075029 2813908.336862319 637850.0922338085 7328911.713162584 0.005195774370852576 1.2982995749594506e-12 11.886625085085484 -0.5311903146302297 SLS(ph)YEEPR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSYEEPR 8 0 Q8IZD4;Q8IZD4-2;F5GZK9 Q8IZD4 DCP1B mRNA-decapping enzyme 1B 1 S(0.001)LS(0.999)YEEPR 134.23 0.0039811 36050000.0 116220.0 105190.0 121060.0 79085.0 124070.0 117260.0 111500.0 127800.0 138810.0 97573.0 True False 114562.68148786241 104946.43901785459 111106.91410511374 84901.1747198262 116772.44653100529 112245.06314641066 117272.92442630997 133738.05455683803 123175.75606589841 114438.36304215 1.0010863354071802 0.9170564505471007 0.9708887050769048 0.7418943478644077 1.0203959880830837 0.9808342251895764 1.0247693282987274 1.168647042841565 1.0763502097677704 1.0 16.8042112406511 -7.057806325208907 1.5614452806002703 1.0875558576793907 0.918058398515606 0.4018924348461552 0.08076222651731176 0.3671442582427776 1.7948264099308924 0.041131413228836615 0.029285944057466155 8.753740636115655e-08 7.057806325208907 -0.16949745916378467 SLS(ph)YSPVER ddPTM_PC-9_AZD4547_30min_R2 1 SLSYSPVER 9 0 Q9UQ35;Q9UQ35-2;I3L4U6 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.005)LS(0.981)YS(0.013)PVER 84.31 0.013306 25391000.0 19219.0 17478.0 35617.0 33842.0 27620.0 27632.0 33940.0 29179.0 17779.0 22631.0 True False 25330.242219966232 23127.421699081508 35144.69530826562 26040.249753687927 23785.43975590369 25904.166671851166 36960.59424950787 24670.0560167154 18718.76164345213 21838.69557834029 1.1598789006926253 1.0590111307755663 1.6092854622289015 1.1923903449395923 1.0891419622834155 1.1861590624278415 1.6924359844168324 1.1296487891512745 0.8571373494494551 1.0 14.414599066445454 -8.002736634862654 24.999884651218125 0.950176720522702 1.2829636109061986 0.3309907731126418 0.201429463311872 123.9956254761878 1132723.699456815 0.11592235003688783 0.05408639140873648 9.937184771340256e-09 8.002736634862654 0.3327868903834966 SLS(ph)YSPVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSYSPVER 9 0 Q9UQ35;Q9UQ35-2;I3L4U6 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SLS(0.963)YS(0.037)PVER;S(0.001)LS(0.659)YS(0.34)PVER 79.20100000000001 0.02049 13084000.0 31187.0 29604.0 36808.0 41942.0 43979.0 39941.0 41097.0 30826.0 34858.0 30078.0 True False 36466.343128672524 32542.88947397988 37685.64231511733 39592.12571779865 35361.63065589306 37846.42364788796 37203.99464348617 30016.850162846793 35367.732305142934 35530.90330268299 1.0263274991356297 0.9159038034229352 1.0606440819722034 1.1143011304981087 0.9952359036484966 1.065169194418711 1.0470883424085884 0.8448096550525969 0.9954076316002994 1.0 15.116786746342298 -7.714854621532362 24.999927211413773 0.9400806173050718 1.031740995325401 0.2773674586283482 0.06285916458087147 144.60904953022634 77604.90742909028 0.029793996410286332 0.01720149909816135 1.928170253015714e-08 7.714854621532362 0.09166037802032934 SLSCLS(ph)DLDGGVALEPR ddPTM_PC-9_AZD4547_30min_R2 1 SLSCLSDLDGGVALEPR 17 0 O95685 O95685 PPP1R3D Protein phosphatase 1 regulatory subunit 3D 1 S(0.104)LS(0.241)CLS(0.655)DLDGGVALEPR 207.85 2.0075e-17 5393300.0 3651.6 3989.3 5068.1 6479.1 4888.1 5090.1 6247.5 6976.0 5075.9 6262.0 True False 4812.7328420016 5278.7632099866 5000.893682562285 4985.443596097138 4209.47168974775 4771.815242341837 6803.515396988813 5898.01949253253 5344.201711344768 6042.769286004461 0.7964449103076425 0.8735668962594086 0.8275830907767332 0.8250263017063758 0.6966130081281152 0.7896735778732682 1.1258936217780648 0.9760457851986535 0.8843961201236606 1.0 12.560994145400436 -7.236324100141011 24.922118250941175 0.9945877010677603 0.8022505555930146 0.6585550209399609 0.06881439133460088 476.937310912688 473269.85126210895 0.02758334501038584 0.021356856094967198 5.803311732102521e-08 7.236324100141011 -0.19233714547474567 SLSDNGQPGT(ph)PDPADSGGTSAK ddPTM_PC-9_AZD4547_30min_R2 1 SLSDNGQPGTPDPADSGGTSAK 22 0 O75691 O75691 UTP20 Small subunit processome component 20 homolog 1 SLSDNGQPGT(0.901)PDPADS(0.098)GGT(0.001)SAK 254.36 9.569599999999997e-146 0.0 35872.0 35340.0 43752.0 55096.0 45395.0 41296.0 39406.0 46763.0 34648.0 41226.0 True False 47278.54981604811 46762.96388863373 43171.81989295103 42394.46842471455 39092.68782473745 38713.75459180535 42913.05766046277 39536.85285683754 36479.42254470607 39782.690288217775 1.1884201262791507 1.1754600694383723 1.085191061242457 1.0656511190564277 0.9826557113538226 0.9731306332309807 1.0786866687387429 0.9938204925408717 0.9169672106240131 1.0 15.279853220684226 -5.528387428351994 1.0930183308750265 0.9922571702173859 1.2086269919339012 0.7857194028859406 0.03896230021291401 0.3211210885470291 0.6553165508234718 0.01446122109367309 0.06029457192122327 2.962187682115473e-06 5.528387428351994 0.2163698217165153 SLSDNGQPGT(ph)PDPADSGGTSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSDNGQPGTPDPADSGGTSAK 22 0 O75691 O75691 UTP20 Small subunit processome component 20 homolog 1 SLSDNGQPGT(0.999)PDPADS(0.001)GGTSAK;SLSDNGQPGT(0.98)PDPADS(0.02)GGTSAK 259.32 1.6681999999999995e-164 0.0 76102.0 85148.0 75107.0 88122.0 104141.0 89634.0 99500.0 86771.0 90366.0 70402.0 True False 88984.56551698595 93600.9307164721 76897.83572488352 83184.81003537883 83735.31863242385 84933.4352483612 90074.63968238259 84493.35319147409 91687.43179432384 83165.32529807462 1.0699719528307556 1.1254802452944783 0.9246381884429881 1.000234289197263 1.0068537378084714 1.021260181980284 1.0830792684276067 1.015968528814619 1.1024718711278403 1.0 16.34369452032322 SLSDNGQPGT(ph)PDPADSGGTSAK ddPTM_PC-9_Lapatinib_30min_R1 2 SLSDNGQPGTPDPADSGGTSAK 22 0 O75691 O75691 UTP20 Small subunit processome component 20 homolog 1 SLSDNGQPGT(1)PDPADSGGTSAK;SLSDNGQPGT(1)PDPADSGGTSAK 250.28 2.613899999999999e-144 0.0 103195.0 89156.0 87102.0 70272.0 69805.0 73538.0 71189.0 68631.0 81791.0 49003.0 True False 101723.42037635464 88949.56475972837 79940.80978344334 75440.03730052002 65699.20714191033 70392.95116545065 74874.81808954787 71819.84680978359 72578.83628258706 57473.103257606825 1.7699308826323221 1.5476729064208916 1.3909255852277789 1.312614649715042 1.1431296279136405 1.2247981608011365 1.3027801501154865 1.249625350624823 1.2628313449035993 1.0 15.810599329079281 -4.84533178053788 0.8814434010465014 1.2120918595761383 2.0475824484281846 0.8373337732167017 0.0817275766156483 0.7989697391723628 0.5159253781697916 0.028920981972124202 0.6357860874444495 1.4278027676604612e-05 4.84533178053788 0.8354905888520463 SLSDS(ph)ESDDSK ddPTM_PC-9_Lapatinib_30min_R1 2 SLSDSESDDSK 11 0 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 S(0.079)LS(0.048)DS(0.863)ES(0.009)DDSK;S(0.004)LS(0.377)DS(0.604)ES(0.015)DDSK 187.62 0.00029219 677140000.0 1979192.0 2546007.0 2433407.0 2365194.0 2631248.0 2247569.0 2237310.0 2260485.0 2312290.0 2146713.0 True False 1950968.3591406385 2540111.877217708 2233341.6696826606 2539138.2568158894 2476483.165872604 2151445.7132092356 2353146.964558097 2365515.3854062106 2051855.5507068401 2517769.4817347294 0.7748796596725892 1.0088738844620457 0.8870318295159811 1.0084871848817696 0.9836020270474963 0.8545046434222807 0.9346157309591312 0.9395281826104205 0.8149497265703304 1.0 21.26371477025956 -9.043426849029881 0.00433151795920994 1.8674259453426199 6.72335237798897e-07 0.03463804658392611 0.07874740178066388 89250.77967172638 160.45471033592486 34964.88470114012 34204.81048341053 9.048428333123693e-10 9.043426849029881 -1.8674252730073821 SLSDSESDDSK ddPTM_PC-9_AZD4547_30min_R2 2 SLSDSESDDSK 11 0 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 0 ; 106.29 0.011299 7013400.0 34194.0 32117.0 38346.0 40660.0 45976.0 41208.0 37584.0 36808.0 35211.0 45727.0 False True 45066.98072061633 42498.19216783386 37837.50698516868 31286.465190737872 39593.02600352744 38631.257245716675 40928.903190144476 31120.16936369513 37072.18157531878 44126.111648215585 1.0213222746636184 0.9631075701081504 0.8574856376836183 0.7090238414878113 0.8972697689561446 0.8754738589634803 0.9275438433469947 0.7052551924763486 0.8401415894259502 1.0 15.429345003523435 -5.171828857652515 3.1697915257689653 0.8404956416878715 1.009810127302817 0.3055256591581095 0.08568579418752105 0.2910310750804538 5.508255058738667 0.02235759275799762 0.07487073348024434 6.732419083333255e-06 5.171828857652515 0.16931448561494555 SLSDSESDDSK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSDSESDDSK 11 0 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 0 107.55 0.010574 4858900.0 24748.0 30534.0 22252.0 24310.0 27311.0 21396.0 20291.0 22648.0 22228.0 24201.0 False True 24395.088981772635 30463.300399003354 20422.526455203977 26097.838495782704 25704.620675491922 20480.942956512048 21341.56869537448 23700.3087605889 19724.44856878315 28384.1106041945 0.8594628636406039 1.073251891658765 0.7195055973388862 0.919452395733198 0.90559894702825 0.7215636678601953 0.7518843550525308 0.8349850763717979 0.6949116300959011 1.0 14.792795916053178 -6.74114329099412 24.6918871457717 0.7873064739681489 0.8968903172976038 0.14591812683658234 0.11232982449172793 353.5572464552794 430130.8382765454 0.03542256487362773 0.035379067085868104 1.814916750875111e-07 6.74114329099412 0.10958384332945492 SLSEQPVMDT(ph)ATATEQAK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSEQPVMDTATATEQAK 18 0 P18615;P18615-3;A0A0A0MT02;P18615-4;A2ABK4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 1 S(0.356)LS(0.066)EQPVMDT(0.572)AT(0.005)ATEQAK 108.72 0.0010149 4088800.0 21582.0 16270.0 20588.0 15920.0 27528.0 26737.0 33269.0 29742.0 25823.0 32899.0 True False 21274.236722345915 16232.32781462581 18895.33411197822 17090.809907563165 25908.85716213034 25593.52083699115 34991.50603353278 31123.92189850915 22914.54181175489 38585.548314838044 0.5513524532231391 0.4206841297725885 0.48969976940076376 0.4429329283624799 0.6714653100359625 0.6632929154760561 0.9068552233084847 0.8066212159162313 0.5938633196238168 1.0 15.235772986668422 -6.61038869013841 1.6132817436855391 0.8055434383954782 0.47059795633316953 0.66137729101087 0.1084709702445412 0.2298141783903208 1.2305914938426905 0.043155272604686504 0.044240126137418095 2.452512953383348e-07 6.61038869013841 -0.3349454820623086 SLSFPILNPALSQPS(ph)QPSSPLPGSHGR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSFPILNPALSQPSQPSSPLPGSHGR 27 0 Q8ND24;E9PN76;Q8ND24-2 Q8ND24 RNF214 RING finger protein 214 1 SLSFPILNPALSQPS(0.592)QPS(0.046)S(0.316)PLPGS(0.046)HGR 119.18 2.5633e-12 9105900.0 10858.0 7888.4 11790.0 7570.3 12375.0 9726.0 12259.0 12757.0 14637.0 16790.0 True False 10703.162928886662 7870.134894461855 10820.67171071612 8127.045115780487 11647.1268301861 9310.041652413367 12893.711036252322 13349.736791718138 12988.426925556909 19692.129128731292 0.5435249209934587 0.39965891158915556 0.5494922179302846 0.41270525206555403 0.5914610225256273 0.47277983967867604 0.6547647007575268 0.6779224686395413 0.6595745356253265 1.0 14.265331484562386 -8.871289763339966 0.36947775663403765 1.0538862872518378 0.452733288436488 0.8477475409880819 0.06407873020968433 0.731217226831806 0.21852872606450316 0.13829775274281494 0.053389095830047896 1.3449626891352336e-09 8.871289763339966 -0.6011529988153497 SLSFPILNPALSQPSQPS(ph)SPLPGSHGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSFPILNPALSQPSQPSSPLPGSHGR 27 0 Q8ND24;E9PN76;Q8ND24-2 Q8ND24 RNF214 RING finger protein 214 1 SLSFPILNPALSQPS(0.012)QPS(0.69)S(0.281)PLPGS(0.017)HGR 151.64 2.9860000000000003e-10 9402500.0 7830.5 5598.9 7124.4 9997.6 13031.0 11587.0 12189.0 14146.0 11303.0 11082.0 True False 9156.048990575246 6154.721790158969 7294.272715437458 9437.46688465653 10477.6690938162 10979.357322252275 11034.369679282023 13774.68248892594 11468.284991824856 13091.078874936275 0.699411337907764 0.47014626135532545 0.5571941613920621 0.7209082593433285 0.8003671197701192 0.8386900290756762 0.8428923074024132 1.0522190432523075 0.8760381861102094 1.0 13.676296378542393 -6.4476205457748685 0.8257504036410694 0.9638469317130541 0.5493156289302578 0.7913076845360842 0.07844221127422822 0.2708508367975274 0.4070472216142536 0.04492613588961304 0.060540824595285106 3.567627100181394e-07 6.4476205457748685 -0.4145313027827964 SLSFPILNPALSQPSQPSS(ph)PLPGSHGR ddPTM_PC-9_AZD4547_30min_R2 2 SLSFPILNPALSQPSQPSSPLPGSHGR 27 0 Q8ND24;E9PN76;Q8ND24-2 Q8ND24 RNF214 RING finger protein 214 1 SLSFPILNPALSQPS(0.026)QPS(0.365)S(0.601)PLPGS(0.008)HGR;SLSFPILNPALSQPSQPS(0.351)S(0.639)PLPGS(0.01)HGR 208.41 2.0424999999999997e-38 25077000.0 40401.0 44840.0 71130.0 99401.0 77126.0 66136.0 81222.0 144437.0 97652.0 85514.0 True False 53247.67760699603 59333.65310600838 70186.76972448354 76485.63518014103 66418.38619166653 62000.50546502425 88450.60065213696 122117.5804820703 102813.68535949083 82520.18088843572 0.64526855168901 0.7190199108533866 0.8505406673717003 0.9268718797835264 0.804874461938732 0.751337488569574 1.071866296218121 1.4798511002680523 1.245921715785999 1.0 16.332459363238257 -7.452677901264843 3.9232892198058757 1.2751204637246483 0.7926576219954731 0.7142660518905393 0.13124362219005306 0.11672678452806375 3.4652062281702545 0.060105949188250525 0.037683650135748245 3.526323072695974e-08 7.452677901264843 -0.4824628417291752 SLSFPILNPALSQPSQPSS(ph)PLPGSHGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSFPILNPALSQPSQPSSPLPGSHGR 27 0 Q8ND24;E9PN76;Q8ND24-2 Q8ND24 RNF214 RING finger protein 214 1 SLSFPILNPALSQPS(0.018)QPS(0.339)S(0.635)PLPGS(0.008)HGR 170.76 5.6347000000000005e-14 7385500.0 22555.0 17886.0 22787.0 26703.0 37744.0 33505.0 33839.0 49089.0 38374.0 33895.0 True False 26373.116018443845 19661.603875543995 23330.32850017874 25206.917482294077 30348.334147571073 31747.93881781844 30633.524946855723 47800.46576409483 38935.14715352447 40039.895187327646 0.6586709554322399 0.49105033326277936 0.5826770622407281 0.6295450416231833 0.7579523873772805 0.792907640474205 0.7650750533570584 1.193820951340136 0.9724088180392435 1.0 15.289150577176889 -7.0778897470226365 0.8385165798093881 1.0635179057129802 0.5699225737066254 0.7830774307376879 0.09512418665293111 0.26679151537075585 0.38312939490812903 0.07025062437144265 0.04870166269793804 8.35815177076388e-08 7.0778897470226365 -0.49359533200635486 SLSFPILNPALSQPSQPSS(ph)PLPGSHGR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSFPILNPALSQPSQPSSPLPGSHGR 27 0 Q8ND24;E9PN76;Q8ND24-2 Q8ND24 RNF214 RING finger protein 214 1 SLSFPILNPALSQPS(0.004)QPS(0.222)S(0.551)PLPGS(0.222)HGR 158.35 5.7774999999999996e-11 9783100.0 19249.0 18313.0 18674.0 11041.0 22268.0 19604.0 22189.0 22053.0 25357.0 27415.0 True False 18974.50573016573 18270.597373647357 17138.695803724564 11852.991971696292 20958.240020572444 18765.582619156026 23337.837848389176 23077.662888434614 22501.027638952422 32153.646221808714 0.5901198762738135 0.568227853463631 0.5330249541683386 0.3686360137798871 0.6518153454819438 0.5836222271559353 0.7258224366653608 0.7177308206116241 0.6997970769389988 1.0 14.972694727922155 -8.529635374212683 0.41940268344738096 1.0180262509756084 0.5128520775105707 0.7674310809913316 0.07509426315223584 0.642981349063597 0.2929156084969334 0.11536449191991428 0.059405979598242564 2.9536880489648444e-09 8.529635374212683 -0.5051741734650377 SLSGS(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 1 SLSGSPLK 8 0 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 SLS(0.018)GS(0.982)PLK 105.2 0.003846 34323000.0 135640.0 146410.0 187400.0 216000.0 185590.0 133390.0 183760.0 178800.0 112150.0 179480.0 True False 178770.6985127329 193734.1692964024 184914.95355501524 166204.53716673332 159824.0320165881 125049.10221331139 200114.28400971022 151170.56841525453 118078.02004123718 173196.45982946022 1.0321844839597842 1.1185804229899667 1.0676601227132112 0.9596301063566105 0.9227904090762628 0.7220072646775941 1.1554178659699796 0.8728271268599039 0.6817576996521983 1.0 17.402049915825472 -5.920758105576604 2.357156233755066 0.8912950420022212 1.0809548016665154 0.2902623129411007 0.12618045952146115 0.38492720643241174 4.337214022925309 0.03915607889720221 0.06391728661157155 1.2001675893566498e-06 5.920758105576604 0.18965975966429416 SLSGS(ph)PLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SLSGSPLK 8 0 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 SLS(0.037)GS(0.963)PLK;S(0.099)LS(0.165)GS(0.735)PLK;S(0.059)LS(0.034)GS(0.907)PLK;S(0.002)LS(0.024)GS(0.974)PLK;S(0.004)LS(0.024)GS(0.972)PLK 108.57 0.0037919000000000004 132624800.0 663672.0 667134.0 660536.0 870481.0 953975.0 693188.0 814319.0 897372.0 717208.0 569889.0 True False 776018.5614804982 733362.6545849927 676285.68333673 821710.7717074796 767050.4469168391 656836.0009922675 737180.8091609874 873816.9358442277 727695.8101757694 673205.3644611585 1.1527218920806321 1.0893594931050272 1.004575600608942 1.2205945096191955 1.1394003782646553 0.9756844429158802 1.0950310976072444 1.297994612006161 1.0809417877384646 1.0 19.360687147317797 SLSGS(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 2 SLSGSPLK 8 0 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 S(0.023)LS(0.032)GS(0.946)PLK;S(0.362)LS(0.199)GS(0.439)PLK 120.45 0.0034152 84189000.0 312000.0 375360.0 348820.0 268180.0 267890.0 302880.0 317800.0 294870.0 295660.0 252510.0 True False 307550.8227862075 374490.87698205013 320141.36608413915 287902.85182225454 252133.23689200456 289926.5284477646 334254.12899265735 308570.7366758592 262359.6573621753 296156.01705157425 1.0384756853771737 1.2645053803409108 1.0809888965665957 0.9721323736337173 0.8513527410388446 0.97896551734512 1.1286420324002686 1.0419195252147215 0.8858832583384133 1.0 18.175997872345114 -5.581394386059305 4.358471111713813 0.9832331270991873 1.1567101949718999 0.3858425415431713 0.08822881949667559 0.20812962151427625 8.063265751656296 0.025340196593357955 0.046702390983601204 2.621836552661262e-06 5.581394386059305 0.17347706787271255 SLSGS(ph)SPCPK ddPTM_PC-9_AZD4547_30min_R2 3 SLSGSSPCPK 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SLSGS(0.989)S(0.011)PCPK;SLS(0.007)GS(0.551)S(0.442)PCPK;S(0.02)LS(0.23)GS(0.739)S(0.011)PCPK 175.74 0.0016530999999999998 132490600.0 300474.0 253424.0 360487.0 446800.0 403639.0 332675.0 331397.0 332463.0 306400.0 379596.0 True False 396018.48175254394 335338.3520235743 355706.70684197877 343797.16299118736 347600.69216630067 311872.7796597455 360890.6909989438 281088.4825897142 322595.67847200215 366306.45958002965 1.0811124712531117 0.9154584726898884 0.9710631563794876 0.9385506425012292 0.9489341044239975 0.8513985257516552 0.9852151977136985 0.7673587927223072 0.8806715525624584 1.0 18.482691616711527 -1.5228787453423198 0.5324044562723775 0.8944431099991588 7.197610482843273 0.3165378336966346 0.06818215662968588 146.5607092621223 1.4177396584877593 0.03414460533264061 1048.8408538255342 0.029999999995718417 1.5228787453423198 6.303167372844114 SLSGS(ph)SPCPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLSGSSPCPK 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SLSGS(0.78)S(0.22)PCPK;SLS(0.003)GS(0.575)S(0.423)PCPK;SLSGS(0.5)S(0.5)PCPK;SLSGS(0.705)S(0.295)PCPK 187.31 0.00011139 174657000.0 1034334.0 918953.0 1077857.0 1251454.0 1226733.0 899852.0 827769.0 915277.0 747325.0 669264.0 True False 1209426.3171722929 1010180.5806912003 1103557.1986754336 1181339.0896486088 986363.4748265219 852662.1770210878 749356.7277914182 891251.9485661448 758253.2143250011 790596.2653090907 1.5297647740588007 1.2777451969068703 1.3958543027571577 1.494238135803429 1.2476196993428679 1.078505192138407 0.947837424324855 1.1273161633488136 0.9590903063886284 1.0 19.59258161447572 -6.635603979203847 2.566412356754539 1.01950975577295 1.4111403616915605 0.8514528830787704 0.07929906623586097 0.10294650881307771 1.3780412450625523 0.02798537139202666 0.027939341472479336 2.3141740578973845e-07 6.635603979203847 0.39163060591861054 SLSGS(ph)SPCPK ddPTM_PC-9_Lapatinib_30min_R1 3 SLSGSSPCPK 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SLSGS(0.633)S(0.367)PCPK;SLSGS(0.64)S(0.36)PCPK;SLSGS(0.5)S(0.5)PCPK 144.7 0.00011411 162549000.0 710927.0 706270.0 713271.0 715446.0 619731.0 480477.0 379362.0 373898.0 460957.0 348090.0 True False 700789.0506119544 704634.6752080998 654628.6116856823 768062.285497892 583279.6410180257 459928.11875659163 399003.50812747807 391270.6660617569 409039.1685675987 408256.89269923087 1.7165394219767318 1.7259590414979593 1.6034722827520203 1.8813210486656382 1.4287073934296972 1.1265654713524402 0.9773344069941523 0.9583932887815614 1.0019161363405176 1.0 18.63911771779648 -6.669504654975421 2.2529497770155444 0.9868459204834792 1.7228193996781664 0.9568478488710838 0.07236750363228472 0.053917598724388366 0.5599346393942445 0.02627844103031032 0.025711339722682365 2.1404019847992046e-07 6.669504654975421 0.7359734791946873 SLSGSS(ph)PCPK ddPTM_PC-9_AZD4547_30min_R2 2 SLSGSSPCPK 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SLSGS(0.019)S(0.981)PCPK;SLS(0.002)GS(0.161)S(0.837)PCPK 167.11 0.00012025 129671600.0 320975.0 275837.0 358051.0 455150.0 447743.0 324512.0 334395.0 347978.0 307840.0 386372.0 True False 423038.3733052538 364995.915963471 353303.0097936326 350222.1994974015 385581.61305675603 304220.2133401766 364155.50719104824 294205.995838945 324111.79393218446 372845.2338824837 1.1346219151042987 0.9789475170775908 0.9475862306583472 0.9393232571340507 1.0341599624102658 0.8159423420068799 0.9766934751962678 0.789083429538153 0.869293112740555 1.0 18.50821737396538 -1.5228787452916335 0.5349854839306882 0.8967157953997709 9.80930202799113 0.43645365747995524 0.07343687103041102 115.67520811850228 1.110194288101184 0.0368037320764578 1177.4783973589742 0.029999999999219706 1.5228787452916335 8.912586232591359 SLSGSS(ph)PCPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSGSSPCPK 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SLSGS(0.184)S(0.816)PCPK;SLS(0.001)GS(0.166)S(0.833)PCPK 134.3 0.00011124 118375000.0 483842.0 421426.0 473625.0 557656.0 564787.0 465397.0 396515.0 439889.0 386193.0 274536.0 True False 565746.8942849005 463262.38817259326 484918.016232814 526412.3422651464 454121.0417074036 440990.76203540515 358954.2286799987 428342.3798509212 391840.3420196252 324307.2035742204 1.744478346610098 1.4284677708880178 1.4952428157268374 1.623190408549382 1.4002804646412186 1.3597932983763672 1.1068339670655791 1.3207920611386958 1.2082381695537923 1.0 18.30700154400723 -6.544472582283983 0.24080186684732818 0.9566624543313665 1.84655993606721 0.777228922261701 0.10114098702502818 2.1250888195925834 0.24350731102012638 0.209463711361937 0.5951487794734364 2.8544827162283696e-07 6.544472582283983 0.8898974817358435 SLSGSS(ph)PCPK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSGSSPCPK 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SLSGS(0.301)S(0.699)PCPK 128.88 0.00026489 136090000.0 333950.0 320220.0 361750.0 360740.0 299580.0 247620.0 180710.0 183900.0 243530.0 152240.0 True False 329187.811761071 319478.55026425875 332008.3113953817 387270.0229933632 281959.2933969414 237029.8698304131 190066.27957917936 192444.66535995624 216101.08691541123 178554.48115295134 1.8436267162574642 1.7892496911941997 1.8594230133657663 2.1689179711016284 1.579121910445992 1.3274932575193743 1.0644721899551035 1.0777924144906028 1.2102809490975315 1.0 17.44600481589938 -6.721580158707762 2.190790665894048 1.1035654439134592 1.9012771243151638 0.9062185870226491 0.11922226263328548 0.08813259874561141 0.8687616415742596 0.04686676015125864 0.044327420667511795 1.8985403918972366e-07 6.721580158707762 0.7977116804017046 SLSKS(ph)DSDLLTCSPTEDATMGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSKSDSDLLTCSPTEDATMGSR 23 1 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 S(0.017)LS(0.263)KS(0.702)DS(0.017)DLLTCSPTEDATMGSR 75.703 0.00057465 19296000.0 130770.0 79424.0 53221.0 79527.0 81244.0 74255.0 84295.0 71004.0 77768.0 75049.0 True False 152906.7781747686 87308.68982507002 54489.99048176645 75071.36002001262 65324.82141493383 70360.93708154325 76309.96735704978 69140.22023495672 78905.20987739864 88654.78961244297 1.7247435682065808 0.9848163895796553 0.6146310957362942 0.846782901952498 0.7368448078271148 0.7936507140688976 0.8607540290901491 0.7798813864113291 0.8900276028214053 1.0 16.435910954987676 -4.782585503613138 3.480366380392309 0.8057550348859082 1.8361331843710595 0.8875816001537917 0.09661155396682837 0.07956065094602241 1.5813785089743593 0.02273702526193709 0.21788538215810926 1.6497361703683655e-05 4.782585503613138 1.0303781494851514 SLSKS(ph)DSDLLTCSPTEDATMGSR ddPTM_PC-9_Lapatinib_30min_R1 2 SLSKSDSDLLTCSPTEDATMGSR 23 1 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 S(0.074)LS(0.237)KS(0.629)DS(0.06)DLLTCSPTEDATMGSR;S(0.062)LS(0.191)KS(0.729)DS(0.018)DLLTCSPTEDATMGSR 77.1 0.0004868 31639600.0 47154.0 45741.0 47103.0 52408.0 58858.0 48797.0 42673.0 44088.0 56872.0 42034.0 True False 46481.575313015455 45635.08952481867 43230.37316283811 56262.25914796294 55396.088159280276 46710.06606136284 44882.39913940741 46136.489431156995 50466.47647129009 49299.520893215675 0.9428403049533893 0.9256700409658285 0.8768923587812641 1.1412333858138048 1.1236638238182874 0.9474750507725689 0.910402339134778 0.9358405233002182 1.0236707285777091 1.0 15.589286005699483 SLSKSDS(ph)DLLTCSPTEDATMGSR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSKSDSDLLTCSPTEDATMGSR 23 1 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 S(0.007)LS(0.091)KS(0.362)DS(0.535)DLLT(0.004)CS(0.001)PTEDATMGSR 63.674 0.0035705999999999997 25311000.0 28204.0 30995.0 30193.0 32859.0 32860.0 30375.0 27167.0 31706.0 32167.0 28895.0 True False 27801.805788019843 30923.232981827117 27710.648088350423 35275.56047441069 30927.239405245673 29075.93205758336 28573.574330848107 33179.176508443634 28544.013726473273 33889.462249832664 0.820367274731753 0.9124734040883109 0.8176774209064722 1.0409005670954508 0.9125916244185427 0.8579638072518229 0.843140387422028 0.9790411032151288 0.8422681220506594 1.0 15.048549124200958 SLSLEAT(ph)SPLSAEK ddPTM_PC-9_AZD4547_30min_R2 4 SLSLEATSPLSAEK 14 0 Q86YC2;H3BN63 Q86YC2 PALB2 Partner and localizer of BRCA2 1 SLSLEAT(0.729)S(0.21)PLS(0.062)AEK;SLSLEAT(0.485)S(0.485)PLS(0.031)AEK;SLSLEAT(0.499)S(0.499)PLS(0.001)AEK;SLSLEAT(0.497)S(0.497)PLS(0.007)AEK 187.16 1.1134e-05 34959800.0 255376.0 251384.0 328680.0 386298.0 374109.0 313993.0 301281.0 345326.0 276926.0 332849.0 True False 336580.25584921625 332638.96191794856 324321.4884443033 297242.9643446052 322170.42294139636 294358.96807305166 328094.42534136685 291963.8015020484 291563.74300436635 321196.05782135 1.0478965966525746 1.0356259169997757 1.009730600817933 0.9254253192295793 1.003033552549354 0.9164463912467282 1.0214771238688545 0.9089893676853261 0.907743840263864 1.0 18.293094660578184 -5.573644874117022 4.305383215126905 0.9542538675669661 1.0385376410315845 0.45061797993335884 0.03954446720160301 0.1798839456245455 7.029787801113371 0.010632695383499056 0.019760449034880688 2.669040266859135e-06 5.573644874117022 0.08428377346461846 SLSLEAT(ph)SPLSAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSLEATSPLSAEK 14 0 Q86YC2;H3BN63 Q86YC2 PALB2 Partner and localizer of BRCA2 1 SLS(0.001)LEAT(0.499)S(0.499)PLS(0.001)AEK;SLSLEAT(0.5)S(0.5)PLSAEK 173.44 0.00035252 13019900.0 90414.0 92329.0 86661.0 114564.0 119352.0 110106.0 127152.0 117537.0 100968.0 76340.0 True False 105719.30444210095 101494.81293889626 88727.32690367287 108145.3505014991 95965.83237550098 104331.84752946477 115107.24205923906 114451.77829074542 102444.46598731035 90179.8376928924 1.172316419576272 1.1254712309921984 0.9838931758319853 1.1992187307964368 1.0641606242662889 1.1569309748013417 1.2764188204822122 1.2691504134273468 1.136001889204826 1.0 16.460517292941717 -6.9960059663003475 23.28172840953214 1.1962295378984424 1.10824273099177 0.067548721101785 0.0916330244357776 87.50925116826373 510090.0666792315 0.0313454461121814 0.027494678195198238 1.0092390211423262e-07 6.9960059663003475 -0.08798680690667249 SLSLEAT(ph)SPLSAEK ddPTM_PC-9_Lapatinib_30min_R1 3 SLSLEATSPLSAEK 14 0 Q86YC2;H3BN63 Q86YC2 PALB2 Partner and localizer of BRCA2 1 SLS(0.001)LEAT(0.642)S(0.358)PLSAEK;SLS(0.001)LEAT(0.645)S(0.355)PLSAEK;SLSLEAT(0.499)S(0.499)PLS(0.001)AEK 263.56 7.2051e-56 21539500.0 171869.0 140364.0 136222.0 149454.0 153773.0 151446.0 128159.0 136542.0 159945.0 118292.0 True False 169418.11654308537 140038.9957819382 125022.35299212634 160445.34572392874 144728.3744693499 144969.00761786915 134794.4459331969 142886.23979107745 141930.30980448175 138738.6145858181 1.221131673030295 1.0093728858400537 0.9011359480946276 1.156457747563017 1.0431729832492074 1.0449074185341325 0.971571226479406 1.0298952473876246 1.0230050965132664 1.0 17.08200985775875 -7.058668878608239 7.226222248755164 1.0083498024635944 1.0575406520581694 0.10451317954214678 0.08101794263226147 0.8051801016344876 86.17596213257326 0.03142265741141979 0.024470268182180302 8.736372062679189e-08 7.058668878608239 0.04919084959457498 SLSNS(ph)NPDISGTPTSPDDEVR ddPTM_PC-9_AZD4547_30min_R2 3 SLSNSNPDISGTPTSPDDEVR 21 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 SLS(0.002)NS(0.998)NPDISGTPTSPDDEVR;S(0.001)LS(0.033)NS(0.945)NPDIS(0.006)GT(0.016)PTSPDDEVR;SLSNS(0.916)NPDIS(0.066)GT(0.017)PTSPDDEVR 289.72 1.8097999999999997e-116 63764200.0 39046.5 41966.8 52801.0 69750.0 47050.9 38030.5 41471.2 45315.9 35546.8 45918.1 True False 51462.47478234624 55531.74739449668 52100.8242404395 53670.21512675763 40518.69469265201 35652.446823025326 45162.056459640255 38313.36891078768 37425.731277769504 44310.52129538191 1.161405311377136 1.2532406699598964 1.1758115841862034 1.2112296032127972 0.9144260439309008 0.8046045449422655 1.0192174485734857 0.8646562439512699 0.8446240347361939 1.0 15.435361679197465 -6.2704717918037 7.4944805183312635 0.9011243178686414 1.2027798191516086 0.8274512667987121 0.06539330845315797 0.05360583750539742 22.244052867023264 0.01939635566048549 0.02304565844949958 5.364487136034515e-07 6.2704717918037 0.30165550128296714 SLSNS(ph)NPDISGTPTSPDDEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLSNSNPDISGTPTSPDDEVR 21 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 SLSNS(0.969)NPDIS(0.025)GT(0.006)PTSPDDEVR;SLS(0.227)NS(0.773)NPDISGTPTSPDDEVR;S(0.008)LS(0.008)NS(0.952)NPDIS(0.024)GT(0.007)PTSPDDEVR;SLSNS(0.999)NPDISGTPTSPDDEVR 320.27 7.724599999999998e-168 106578300.0 102780.0 97338.0 127464.0 120078.0 112017.0 88456.0 97698.0 85997.0 89498.0 71314.3 True False 120178.62400246771 107001.07335556866 130503.22516991176 113350.41895812846 90068.07297076253 83817.21164211165 88443.33816773286 83739.6698713534 90806.73893641884 84243.01806631197 1.4265707326376769 1.2701476729067644 1.5491280840293022 1.3455170714432925 1.0691458477884228 0.9949454989389727 1.049859563413488 0.994025045558525 1.077914122983346 1.0 16.36226950241955 -6.24959359526551 3.615318314182133 1.0255125700134193 1.406931400719921 0.8769314673534655 0.06778940521284595 0.07406879195436271 2.1222541443804075 0.02053851695719653 0.025624554742291295 5.628678000840996e-07 6.24959359526551 0.3814188307065016 SLSNS(ph)NPDISGTPTSPDDEVR ddPTM_PC-9_Lapatinib_30min_R1 2 SLSNSNPDISGTPTSPDDEVR 21 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 SLSNS(0.706)NPDIS(0.032)GT(0.242)PT(0.017)S(0.004)PDDEVR;SLSNS(1)NPDISGTPTSPDDEVR 315.59 2.7953999999999993e-167 51259000.0 61184.0 52386.0 60343.0 42508.0 44001.0 34055.0 23771.8 30643.4 29589.2 18950.0 True False 60311.50494022854 52264.703435586234 55381.83147071607 45634.18012253107 41412.94768929444 32598.547036082353 25002.587487689278 32067.204233231645 26256.5527079107 22225.48225071219 2.7136196308314493 2.351566676755078 2.491816863453724 2.053236893029341 1.8633092961556506 1.4667194470004254 1.1249514051326421 1.4428125280478037 1.1813715631330943 1.0 14.439927102683809 -6.353105387912251 0.7827192199285563 1.1471887194405797 2.6398048702581223 0.947449124886381 0.13353247060154608 0.14061644545304955 0.18865771727646505 0.07646408047057081 0.11798589125267889 4.4350100886158653e-07 6.353105387912251 1.4926161508175426 up SLSNSNPDIS(ph)GTPTSPDDEVR ddPTM_PC-9_AZD4547_30min_R2 2 SLSNSNPDISGTPTSPDDEVR 21 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 SLSNS(0.01)NPDIS(0.903)GT(0.085)PT(0.001)SPDDEVR;SLSNS(0.008)NPDIS(0.785)GT(0.204)PT(0.002)S(0.001)PDDEVR 183.06 2.4787999999999998e-14 60579100.0 36783.0 32168.0 48312.0 60190.0 43882.0 36813.0 35641.0 40074.0 37189.0 38835.0 True False 48479.22886607098 42565.676920474514 47671.35131349995 46314.12542622998 37789.741758456374 34511.077290491354 38812.979954234244 33881.48410890892 39154.73461715177 37475.39847045403 1.2936281092325805 1.1358298686012296 1.272070565202516 1.235854115407058 1.0083879905439879 0.9208995420742551 1.035692255142658 0.9040993689665878 1.0448116955453255 1.0 15.193656197770395 -6.294137628136605 4.865870362514063 0.9779260137163187 1.2309822475522958 0.8227167143921661 0.056592706965987775 0.07495406296831564 4.623170234538755 0.016543696435000206 0.019445826527359666 5.079984320948022e-07 6.294137628136605 0.2530562338359771 SLSNSNPDIS(ph)GTPTSPDDEVR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSNSNPDISGTPTSPDDEVR 21 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 SLSNSNPDIS(0.382)GT(0.273)PT(0.273)S(0.071)PDDEVR 184.51 5.6768e-15 48596000.0 41131.0 34152.0 41095.0 37554.0 27531.0 23796.0 14889.0 21456.0 29272.0 15276.0 True False 40544.4643974984 34072.923142292624 37716.32773128743 40315.84643647156 25911.680708028558 22778.300551185323 15659.879567563486 22452.924088978958 25975.07911217477 17916.436246009464 2.2629759535202703 1.901769005534329 2.1051244350945075 2.2502157171714954 1.4462519416382194 1.271363358115303 0.8740510307149626 1.2532025778273794 1.4497905027268028 1.0 14.128996079360506 -6.427187941759829 3.120357998153164 1.1733099446448703 2.112499702655248 0.8688066839418362 0.17620407831949134 0.09276306692062591 1.7312605683893805 0.060353171561718405 0.06803589166805009 3.739487262317918e-07 6.427187941759829 0.9391897580103776 SLSNSNPDISGT(ph)PTSPDDEVR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSNSNPDISGTPTSPDDEVR 21 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 SLSNS(0.045)NPDIS(0.269)GT(0.622)PT(0.054)S(0.011)PDDEVR 160.84 1.1374000000000002e-05 10809000.0 19138.0 17680.0 20898.0 16416.0 12858.0 11936.0 9438.0 9267.5 14707.0 10867.0 True False 18865.088610520637 17639.063046255957 19179.84710861283 17623.287402170652 12101.717719800634 11425.525104174978 9926.653459511335 9698.1018826721 13050.542788424234 12745.346470632685 1.4801550239523749 1.383961047029924 1.504850978575299 1.3827232898515174 0.9495008823561545 0.8964468035844466 0.7788453207124602 0.7609131619150625 1.0239457058695713 1.0 13.63768297179301 -6.270304719140374 3.1299374328960456 0.8730040302768627 1.45120889203392 0.9093078436243266 0.08326025494933173 0.06840559301966133 1.3794128979722107 0.026652830799931696 0.03296723630783172 5.366551246005203e-07 6.270304719140374 0.5782048617570572 SLSPGAASSSS(ph)GDGDGKEGLEEPK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSPGAASSSSGDGDGKEGLEEPK 24 1 Q6ZN18-2;Q6ZN18 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 SLS(0.001)PGAAS(0.263)S(0.263)S(0.084)S(0.388)GDGDGKEGLEEPK 72.585 0.00022722 19735000.0 19613.0 34064.0 34578.0 34159.0 48587.0 39057.0 37827.0 44411.0 33873.0 36413.0 True False 19333.315023416304 33985.12690088594 31735.13031493992 36671.16681108355 45729.20818571729 37386.62315631388 39785.49697106753 46474.49719032647 30057.86604149684 42706.93853272734 0.4526972826347814 0.7957753018246047 0.7430907343222586 0.8586699976862441 1.0707676493990295 0.8754226933795224 0.9315932805761518 1.0882188887108346 0.7038169223594144 1.0 15.382182860953591 -4.458997671957882 0.828938609505848 0.9426284152259929 2.256193254991833e-16 0.6093072136528179 0.11335977985457549 2.5761200433452927 0.9486036253992155 0.03970918854875521 2.521601412804562 3.4753802442103193e-05 4.458997671957882 -0.9426284152259927 SLSPS(ph)LLGYQQPALMAAPLSLADAHR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSPSLLGYQQPALMAAPLSLADAHR 26 0 Q13469-3;Q13469-4;Q13469-2;Q13469;Q13469-5 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 S(0.111)LS(0.41)PS(0.479)LLGYQQPALMAAPLSLADAHR 89.35600000000001 4.78e-07 7048800.0 1518.4 0.0 0.0 0.0 1381.0 1387.2 1448.3 859.82 1580.3 1919.2 True False 1496.7473375595423 0.0 0.0 0.0 1299.7722951504636 1327.8726897211407 1523.2858874136741 899.7703761272321 1402.309972703259 2250.931162826748 0.6649458509783605 0.0 0.0 0.0 0.5774376029865761 0.5899215007772967 0.6767358827182935 0.39973251558581163 0.6229910518197369 1.0 11.136306222144066 -6.309752803304125 7.730000767603482 0.6145656702875122 0.14277971880760246 0.5033082006656571 0.23115614584320981 0.24881367977782015 36.065265457783845 0.07076791171944016 0.08064085172433923 4.900576766275888e-07 6.309752803304125 -0.47178595147990976 SLSPSHLT(ph)EDR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSPSHLTEDR 11 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 SLS(0.003)PS(0.008)HLT(0.989)EDR 110.31 0.0047748999999999995 2737500.0 15842.0 10862.0 11544.0 11772.0 12687.0 13507.0 7332.1 13695.0 15444.0 8759.1 True False 15616.090174933002 10836.849706359293 10594.896881128652 12637.752150240804 11940.775603601694 12929.337096354855 7711.720261759174 14331.31969605549 13704.534087470172 10273.098764232882 1.5200953999685503 1.0548764258053454 1.0313243476268477 1.2301791738088577 1.1623343528220564 1.2585625226703756 0.7506712861175366 1.3950337697474329 1.3340214478599461 1.0 13.326583799518616 -4.753526671366521 24.997526721781984 1.139972354018651 1.5200960888991173 0.2966486640073266 0.17765293871013194 387.8018783081781 1225031.057449165 0.0439946375895431 0.47074925404441165 1.7638974347564084e-05 4.753526671366521 0.38012373488046625 SLSQGST(ph)NATVLDVAQTGGHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSQGSTNATVLDVAQTGGHK 21 0 A0A2R8Y661;H0Y8T6 A0A2R8Y661 RAPGEF2 1 S(0.085)LS(0.07)QGS(0.335)T(0.508)NAT(0.002)VLDVAQTGGHK 110.89 0.0017563 0.0 10304.0 11216.0 11656.0 15844.0 21153.0 20481.0 20244.0 18630.0 19157.0 19046.0 True False 12048.26368672337 12329.450356038324 11933.923245626162 14956.312046941053 17008.22149808104 19406.940305260094 18326.34176613219 18140.98224011665 19437.13488351665 22498.88903194696 0.5355048273546138 0.5480026297534649 0.5304227790394791 0.6647578031832622 0.7559582819369645 0.862573270960335 0.8145442977255444 0.8063056897768434 0.8639153184816006 1.0 14.457566144206343 -6.203636566359814 1.3083176122965197 0.8599696058913485 0.5279215626976215 0.886740309504327 0.051746356914359255 0.13640313772850926 0.47341700190978603 0.01936554347276226 0.0291171568371168 6.256960793067685e-07 6.203636566359814 -0.33204804319372705 SLSRPTTETQFS(ph)NMGMEDVPLATSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSRPTTETQFSNMGMEDVPLATSK 25 1 F8VS10;Q86XZ4 F8VS10 SPATS2 Spermatogenesis-associated serine-rich protein 2 1 S(0.008)LS(0.022)RPT(0.06)T(0.06)ET(0.209)QFS(0.641)NMGMEDVPLAT(0.001)S(0.001)K 40.533 0.04635 5692800.0 15635.0 13139.0 8265.5 15731.0 21627.0 15942.0 13748.0 28397.0 21193.0 18205.0 True False 18281.696694673894 14443.353087374058 8462.580867083307 14849.643070590115 17389.34460071852 15105.97345571293 12445.689913099455 27651.60883910855 21502.907531783065 21505.422389299296 0.8500970761574314 0.671614480567506 0.3935091677759434 0.6905069243363955 0.8086027926320173 0.7024262617240843 0.5787233418531785 1.2857970579953586 0.9998830593758771 1.0 14.392412847170675 -7.754229078097763 24.999995589284755 1.1071300649012692 0.6674268816236034 0.6620334172437805 0.13887921269437367 94.25104796930131 326796.14098598645 0.06856757567090778 0.03853134151624214 1.7610468987830278e-08 7.754229078097763 -0.4397031832776658 SLSRT(ph)PETLLPFAEAEAFLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSRTPETLLPFAEAEAFLK 20 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.287)LS(0.287)RT(0.341)PET(0.085)LLPFAEAEAFLK 52.707 0.024886000000000002 4630500.0 8613.8 4736.6 9512.2 13538.0 18112.0 16333.0 13416.0 21580.0 15090.0 9994.6 True False 10071.946209695037 5206.818344901132 9739.006923219393 12779.50975078819 14563.083618079889 15476.468727396763 12145.139356571302 21013.547865900025 15310.662702524734 11806.54186278993 0.8530818191089696 0.4410112974156466 0.8248822590392296 1.0824092184913783 1.233475795650004 1.3108384239226858 1.0286788034732264 1.7798224162595264 1.2967948515711074 1.0 13.527298840645475 -5.850772108281687 1.6888698477646453 1.310503101131317 0.6346410931983094 0.5709263524995697 0.2218686996750385 0.24680804980261284 1.435322515642003 0.07111350387922277 0.13773956482656755 1.4100285027886958e-06 5.850772108281687 -0.6758620079330077 SLSS(ph)DRGR ddPTM_PC-9_AZD4547_30min_R2 1 SLSSDRGR 8 1 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 SLS(0.059)S(0.941)DRGR 68.626 0.020328 2694100.0 6340.6 1144.6 5647.6 10525.0 6625.3 6412.5 1515.6 3657.7 5352.4 6130.0 True False 8356.778907327018 1514.569566127055 5572.70913392371 8098.6238596290195 5705.491456002486 6011.525361292906 1650.4854638937563 3092.4865105843205 5635.316936858833 5915.390565826783 1.4127180300831086 0.25603881083976515 0.9420695171198427 1.3690767785334035 0.9645164410551547 1.016251639582599 0.27901546745342776 0.5227865305208447 0.9526534003374291 1.0 12.530257710839908 -7.15869189938725 20.74716780728475 0.6483386810098709 0.9733616988338823 0.14768788776580577 0.35150019613937555 17.359873927713117 3492.456521609944 0.13518426112425524 0.10471338524478545 6.939179161524089e-08 7.15869189938725 0.32502301782401144 SLSS(ph)GSNFCSEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSSGSNFCSEQK 13 0 O95243-3;O95243-5;O95243-2;O95243 O95243-3 MBD4 Methyl-CpG-binding domain protein 4 1 SLS(0.297)S(0.703)GS(0.001)NFCSEQK 134.4 4.6408e-05 8273100.0 19987.0 27982.0 20150.0 23500.0 39148.0 29571.0 41947.0 33904.0 27234.0 29733.0 True False 23370.404338755805 30759.86803340445 20630.452419300556 22183.37118802796 31477.230426269423 28020.24470322964 37973.47649001909 33014.05592425738 27632.2457283339 35123.357533701506 0.6653807033206172 0.8757667316938534 0.5873713069573505 0.6315845848946134 0.8961908153588802 0.797766690623005 1.0811459711271294 0.9399459004618163 0.7867199399095104 1.0 15.10014314201079 -6.336435175159238 5.714901081363216 0.9182283023362229 0.6963572255046421 0.517748981879188 0.10727780987407425 0.19836268559827738 11.499441646991968 0.03441870118491998 0.039252841994650706 4.6085555302800045e-07 6.336435175159238 -0.2218710768315808 SLSS(ph)PGGPSKPK ddPTM_PC-9_AZD4547_30min_R2 1 SLSSPGGPSKPK 12 1 J3KRY8;Q9BZE9-3;Q9BZE9;Q9BZE9-2;J3QL04;J3QR12;Q9BZE9-4 J3KRY8 ASPSCR1 Tether containing UBX domain for GLUT4 1 SLS(0.292)S(0.708)PGGPSKPK 94.538 0.023541 12733000.0 41276.0 42156.0 46699.0 52638.0 53258.0 55175.0 51072.0 55992.0 58446.0 58252.0 True False 54400.90940586541 55782.102594489064 46079.74074741543 40503.12234899309 45864.04599999707 51724.89852777174 55617.30906042617 47339.72296815957 61535.33624012618 56212.61521052884 0.9677704764690597 0.9923413523027276 0.8197402055541532 0.7205343888965106 0.8159030820435225 0.9201653104743552 0.9894097410719441 0.8421547866232819 1.0946890837521532 1.0 15.77860631532145 -8.259876788990866 24.998108573879644 1.0473445510561177 0.8820717353132796 0.370619899286293 0.08538760896010136 157.35801625111037 2517500.533108463 0.0723940044692406 0.024021210976823776 5.496968028276644e-09 8.259876788990866 -0.16527281574283803 SLSS(ph)PPSSK ddPTM_PC-9_AZD4547_30min_R2 1 SLSSPPSSK 9 0 Q5VW31;A0A1B0GWB8;A0A2R8Y7V8;Q5VW30;Q5VW27;A0A1B0GWI9;A0A1B0GU97;A0A0A0MRX8;A0A1B0GWJ4;A0A1B0GVN4;U3KQE8;A0A1B0GW37;Q5VW26;O00712-4;O00712;O00712-5;O00712-6 Q5VW31 NFIB Nuclear factor 1;Nuclear factor 1 B-type 1 SLS(0.096)S(0.869)PPS(0.028)S(0.006)K 67.334 0.046031 3012400.0 27288.0 28164.0 30284.0 54687.0 41001.0 34811.0 30709.0 40125.0 32939.0 34253.0 True False 35965.016374339924 37267.462222962095 29882.414372785912 42079.75705572755 35308.718878776504 32634.26266697348 33442.04150878421 33924.60323077231 34680.088293698725 33053.8128958018 1.0880746644181518 1.127478464903378 0.9040534738605394 1.2730681688184948 1.0682192396406136 0.9873070550090272 1.011745350353566 1.0263446258897746 1.0492008411563158 1.0 15.0125290817992 -6.536643082384647 17.888491288219292 1.0176327105369893 1.0969272150833336 0.17892217689555967 0.08460220178301703 15.16417949731351 19703.194697054514 0.02746022507760416 0.02752341932677516 2.906410257610283e-07 6.536643082384647 0.07929450454634424 SLSS(ph)PPSSK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSSPPSSK 9 0 Q5VW31;A0A1B0GWB8;A0A2R8Y7V8;Q5VW30;Q5VW27;A0A1B0GWI9;A0A1B0GU97;A0A0A0MRX8;A0A1B0GWJ4;A0A1B0GVN4;U3KQE8;A0A1B0GW37;Q5VW26;O00712-4;O00712;O00712-5;O00712-6 Q5VW31 NFIB Nuclear factor 1;Nuclear factor 1 B-type 1 SLS(0.003)S(0.937)PPS(0.049)S(0.011)K 99.973 0.0063619 0.0 106730.0 89265.0 96544.0 91003.0 95392.0 102570.0 80890.0 87829.0 104860.0 72786.0 True False 105208.01062811488 89058.3123769253 88606.52499061698 97695.66419710878 89781.23010788785 98183.32020234816 85078.08840219023 91909.85597552833 93049.56257524742 85366.96311875124 1.2324206787321623 1.0432409578988904 1.0379486601550916 1.1444200499578212 1.0517093126880486 1.1501325174912043 0.996616083013763 1.0766443202117368 1.0899949954387993 1.0 16.38139023667692 -1.5228787452803376 0.0909466470665604 0.9667901693912481 1.421115264839946 0.2526914198794802 0.06090130983653777 255.5669437083453 1.67552865930679 1.0812241556778304 14.480768300735473 0.029999999999999995 1.5228787452803376 0.45432509544869804 SLSS(ph)PTDNLELSLR ddPTM_PC-9_AZD4547_30min_R2 1 SLSSPTDNLELSLR 14 0 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 S(0.023)LS(0.126)S(0.71)PT(0.141)DNLELSLR 175.27 1.7963e-05 10322000.0 65156.0 59255.0 81049.0 101350.0 96137.0 83956.0 68663.0 89243.0 82320.0 86523.0 True False 85874.25267100893 78408.01995531944 79974.23730352415 77985.32334189094 82790.0369954131 78706.21804798559 74773.87398214376 75452.54495012606 86671.26714038927 83493.85610555168 1.0285098410408544 0.9390873007014696 0.9578457749324922 0.9340246933056136 0.9915704083753323 0.9426587981334383 0.895561391818049 0.9036897859255666 1.0380556268813452 1.0 16.34938242034375 SLSS(ph)PTDNLELSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSSPTDNLELSLR 14 0 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 SLS(0.008)S(0.992)PTDNLELSLR;S(0.004)LS(0.025)S(0.911)PT(0.06)DNLELSLR 244.0 6.458599999999999e-35 23060000.0 180197.0 168432.0 188450.0 199883.0 238240.0 193327.0 212230.0 186846.0 191855.0 158368.0 True False 210700.79304701957 185152.81583169088 192943.36270060443 188684.20353942955 191558.58222014998 183188.59178726742 192126.0379878601 181941.49047970166 194660.51642099986 187078.86475960203 1.1262672206065176 0.9897046150542653 1.0313477310680623 1.008581080400987 1.023945609603225 0.9792051711595875 1.026978853195115 0.9725389915824968 1.0405265002604134 1.0 17.513287053705803 -4.755965577750274 24.998814171408544 1.0081588439659572 1.126267407318955 0.7276977925801176 0.021686863465672952 82.86241763407303 378391.65059668286 0.004906786579786223 0.04133007361274143 1.754019520198591e-05 4.755965577750274 0.11810856335299769 SLSS(ph)PTDNLELSLR ddPTM_PC-9_Lapatinib_30min_R1 2 SLSSPTDNLELSLR 14 0 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 SLS(0.026)S(0.686)PT(0.288)DNLELSLR;SLS(0.011)S(0.877)PT(0.111)DNLELSLR 155.06 0.00021187 15597400.0 83341.0 78014.0 83646.0 63021.0 87079.0 84859.0 69707.0 76462.0 86072.0 64996.0 True False 82152.54205713236 77833.36337616597 76768.94876289729 67655.77457189301 81957.18442390104 81229.77838599069 73316.08738102955 80014.70365825434 76377.66498165845 76230.47199827389 1.0776863884430963 1.0210269113633244 1.0070637994296505 0.8875161441139308 1.075123664795842 1.0655814696756698 0.9617687711902094 1.049641981228532 1.0019308942936611 1.0 16.218080188463407 -4.774241239032334 3.10284343366584 1.0069270400134442 1.0892015677179718 0.14871866837717096 0.05127396673457708 0.768724600567255 10.85858874667179 0.01334784089481941 0.15871382065309664 1.6817396399362436e-05 4.774241239032334 0.08227452770452759 SLSS(ph)PTVTLSAPLEGAK ddPTM_PC-9_AZD4547_30min_R2 2 SLSSPTVTLSAPLEGAK 17 0 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 SLS(0.072)S(0.761)PT(0.167)VTLSAPLEGAK;S(0.109)LS(0.204)S(0.687)PTVTLSAPLEGAK 252.01 2.3986999999999997e-48 459687000.0 57874.0 53154.0 96026.0 142865.0 117536.0 77635.0 77343.0 127134.0 71921.0 75616.0 True False 76276.72814601823 70334.9910168772 94752.63249772624 109929.68149224704 101218.15521904014 72780.47117722797 84226.37716675561 107488.36154868569 75722.59723036835 72968.70685571925 1.0453347939526996 0.9639062284048738 1.2985379155078116 1.5065318576853852 1.387144703265448 0.9974203232234404 1.1542807978397658 1.473074776578157 1.037740704108877 1.0 16.154990266235615 -8.493830989187042 24.187778255544668 0.9999996437199448 1.228041633525322 0.17695153236182937 0.18156478453603042 713.3568419188325 594005.7190297572 0.18894290997259602 0.04878484957469711 3.207517324799303e-09 8.493830989187042 0.22804198980537715 SLSS(ph)PTVTLSAPLEGAK ddPTM_PC-9_Lapatinib_30min_R1 2 SLSSPTVTLSAPLEGAK 17 0 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 SLS(0.008)S(0.991)PT(0.001)VTLSAPLEGAK;S(0.011)LS(0.3)S(0.689)PTVTLSAPLEGAK 178.01 3.6668e-06 330726000.0 207865.0 173760.0 182764.0 157045.0 184601.0 152206.0 137075.0 133523.0 172148.0 128978.0 True False 204900.80698222766 173357.66939578275 167737.84940944216 168594.61318676206 173743.13211952994 145696.50418951554 144172.0727868739 139726.9660296763 152758.87944119496 151271.67544761786 1.3545219643791175 1.1460021770950293 1.1088516664676342 1.1145154087034803 1.148550325799052 0.963144645277411 0.9530672041561251 0.9236822796879826 1.0098313447588678 1.0 17.206782352825982 -1.5228787452803376 0.32717519972161596 0.9531338934319046 4.743791521709973 0.7965945187974202 0.055486746646567726 26.590836102492624 0.3788889151791871 0.054893961776318896 60.77016487210267 0.029999999999999995 1.5228787452803376 3.790657628278068 SLSS(ph)SLDDTEVKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSSSLDDTEVKK 13 1 O95292 O95292 VAPB Vesicle-associated membrane protein-associated protein B/C 1 SLS(0.288)S(0.696)S(0.015)LDDTEVKK 84.734 0.0124 4400000.0 11880.0 17955.0 15658.0 11831.0 25696.0 9729.0 16747.0 12933.0 12716.0 13962.0 True False 13891.0493593045 19737.453739538883 16031.346103295677 11168.147426619518 20661.053260279412 9218.794113074335 15160.6029222197 12593.52245364619 12901.947443691484 16493.200076868816 0.8422288758132662 1.1967024984569266 0.9719973097142698 0.6771364789470108 1.2527013050218119 0.5589451452785926 0.9192032383989545 0.7635584601503865 0.7822585904227314 1.0 14.009583722965303 -6.76770859729788 24.999312117424093 0.7971661982407858 0.9815630899797169 0.1944416879465718 0.1860424079526738 254.54168389890668 1015010.7762029063 0.06223256411069057 0.05622952670325054 1.7072275194786797e-07 6.76770859729788 0.18439689173893103 SLSS(ph)SLDDTEVKK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSSSLDDTEVKK 13 1 O95292 O95292 VAPB Vesicle-associated membrane protein-associated protein B/C 1 S(0.001)LS(0.035)S(0.482)S(0.482)LDDTEVKK 66.436 0.017165 11167000.0 89418.0 81242.0 39310.0 32379.0 37085.0 46626.0 36771.0 38702.0 52236.0 17585.0 True False 88142.8829227469 81053.88914049376 36078.08354098818 34760.259673177614 34903.73321191525 44631.91467051464 38674.82245811517 40500.23620859729 46352.63161053432 20624.543819460378 4.273688848311849 3.9299724566036227 1.749279104391465 1.6853832005912985 1.692339647240182 2.1640194838346924 1.8751843820964116 1.9636912487917972 2.2474500292606763 1.0 14.332074589250663 -5.232342711053087 5.153780664957619 1.8360131249796565 4.156894901301513 0.8869982713686322 0.32919094775492225 0.052904426105362314 4.000616989064226 0.08151294745220035 0.21523556713589825 5.856758128170959e-06 5.232342711053087 2.3208817763218565 SLSS(ph)SPVK ddPTM_PC-9_AZD4547_30min_R2 1 SLSSSPVK 8 0 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 SLS(0.001)S(0.499)S(0.499)PVK 82.645 0.016176 7518400.0 62505.0 58315.0 63433.0 75503.0 65768.0 63431.0 63062.0 63514.0 53435.0 48619.0 True False 82380.28981523452 77164.18333802144 62591.836973614096 58096.949859721564 56637.24843831547 59464.64954263865 68674.39583271835 53699.37070652393 56259.46501028543 46916.863608471846 1.7558780250681332 1.6447003785668186 1.334101049378582 1.2382956871232738 1.2071831764152368 1.2674472453845151 1.463746519925465 1.1445643757147346 1.199130987948789 1.0 15.517818952000614 -5.245192383191124 2.1336309372573288 1.2343867909821153 1.760571174775168 0.7551236431945892 0.10908390360249855 0.17327996838506413 1.4374090787821292 0.030329325520058487 0.11801547207637746 5.686009969350282e-06 5.245192383191124 0.5261843837930527 SLSS(ph)SPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSSSPVK 8 0 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 SLS(0.007)S(0.496)S(0.496)PVK;SLS(0.001)S(0.5)S(0.5)PVK 83.78299999999999 0.014566999999999998 8917100.0 97975.0 101474.0 86835.0 100198.0 117112.0 119097.0 107405.0 105521.0 95717.0 82200.0 True False 114560.23240554391 111547.66810169688 88905.47572357123 94584.23090629897 94164.74429552631 112851.34366171378 97230.82085513868 102751.1855587413 97116.68004622663 97102.20930515786 1.1797901739343712 1.1487655008048485 0.9155865387591008 0.9740687836365723 0.9697487314588267 1.1621913082024937 1.0013244966402015 1.0581755687538552 1.0001490258684362 1.0 16.567216500295203 -5.113292125455159 6.876179519207894 1.0148331126436252 1.1720591179781266 0.5022350936077336 0.061533496534830985 0.19605311009263482 10.333731981843238 0.01636046158917155 0.044381837276430844 7.703851000468996e-06 5.113292125455159 0.15722600533450137 SLSS(ph)SPVK ddPTM_PC-9_Lapatinib_30min_R1 2 SLSSSPVK 8 0 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 SLS(0.002)S(0.499)S(0.499)PVK;SLS(0.114)S(0.747)S(0.138)PVK 76.17 0.025336 12550300.0 148761.0 123354.0 142447.0 116689.0 143475.0 132594.0 129226.0 128727.0 133865.0 132383.0 True False 146639.640860574 123068.38139184697 130735.55752132107 125270.69832309299 135036.08258270318 126923.26371171046 135916.6899723259 134708.12636101776 118787.71403905697 155265.22516074026 0.9444461289304381 0.7926332587637631 0.8420144136330299 0.8068174840400028 0.8697123418518563 0.8174609838121291 0.8753839749474903 0.8676001095645177 0.7650632259482476 1.0 17.244375219126788 -11.230781753985699 3.0243619072392196 1.0206983762035347 0.8416181862210388 0.4904696397634297 0.04820068254388683 33810954.06767725 31374284.917343087 5306864.020902656 0.011215211502005818 5.877846577590015e-12 11.230781753985699 -0.17908018998249586 SLSS(ph)SPVKK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSSSPVKK 9 1 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 SLS(0.109)S(0.532)S(0.358)PVKK 77.288 0.010671 114010000.0 620720.0 471070.0 548910.0 535380.0 529990.0 602500.0 507810.0 426850.0 624540.0 552570.0 True False 611868.4189738918 469979.26635745517 503780.7386538741 574753.6311753249 498817.0302004305 576732.4794960977 534101.9170665874 446683.00929253723 554197.7285022425 648080.9882467554 0.9441233890060113 0.7251860105152654 0.7773422578198832 0.8868546394644256 0.7696831711571624 0.8899080361180229 0.8241283524015817 0.6892394891893722 0.8551365316262493 1.0 19.305814586992774 -11.550788810744201 1.665687274949391 1.2079425892052489 0.8131510550164116 0.34343142853085096 0.07524915569418213 295556.6757440403 76636.26474429552 234704.27053781474 0.019782979259850963 2.8132685375177777e-12 11.550788810744201 -0.3947915341888373 SLSSPT(ph)VTLSAPLEGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSSPTVTLSAPLEGAK 17 0 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 SLS(0.029)S(0.113)PT(0.685)VT(0.167)LS(0.006)APLEGAK 117.93 0.0007472000000000001 0.0 12349.0 11783.0 15049.0 13681.0 19196.0 14086.0 14616.0 19351.0 15355.0 11701.0 True False 14439.441796132252 12952.738368865863 15407.825233650314 12914.497924400452 15434.681599638996 13347.305363014202 13231.466669323652 18843.056754079298 15579.537826193979 13822.298674934964 1.044648371136445 0.9370900364317882 1.114707878624451 0.9343234600927343 1.1166508525552186 0.9656357221695618 0.957255155636109 1.363236115585381 1.1271307466713587 1.0 13.754709938196138 -7.729403635390732 24.999975987076127 1.1838880982220488 1.0107439068060653 0.3073772588895295 0.10418116541430875 186.48105188053265 145525.6862027511 0.045650112637340194 0.026353356639323665 1.8646458743619923e-08 7.729403635390732 -0.17314419141598347 SLSSS(ph)PQAQPPRPAELSDEEVAELFQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSSSPQAQPPRPAELSDEEVAELFQR 27 1 A0A087WXA6;A0A087WT45;Q4V328-4;Q4V328 A0A087WXA6 GRIPAP1 GRIP1-associated protein 1 1 S(0.013)LS(0.052)S(0.197)S(0.51)PQAQPPRPAELS(0.228)DEEVAELFQR;S(0.012)LS(0.073)S(0.206)S(0.686)PQAQPPRPAELS(0.022)DEEVAELFQR 57.896 0.014658000000000001 2368400.0 3587.2000000000003 3715.1 4548.5 6214.299999999999 5000.5 6565.7 6012.700000000001 6797.299999999999 7049.2 5900.9 True False 4194.442109570462 4083.9105757594475 4656.95349028231 5866.132918032429 4020.687921389605 6221.383133745726 5443.133527821723 6618.878077334667 7152.281214223814 6970.686458501303 0.6017258321029499 0.5858692110270999 0.6680767407925495 0.8415430751268718 0.5767994221696858 0.8925065229634963 0.7808604733875804 0.9495303104993946 1.0260512012415997 1.0 12.76708502131679 -7.130094801489796 0.5139254644337771 1.0395531359681074 0.5973717788576984 0.7303744912849932 0.08624968162780385 0.4894804032679645 0.276766503981792 0.08021122154610676 0.07704380686039265 7.41148439462769e-08 7.130094801489796 -0.44218135711040896 SLSSS(ph)PQAQPPRPAELSDEEVAELFQR ddPTM_PC-9_Lapatinib_30min_R1 1 SLSSSPQAQPPRPAELSDEEVAELFQR 27 1 A0A087WXA6;A0A087WT45;Q4V328-4;Q4V328 A0A087WXA6 GRIPAP1 GRIP1-associated protein 1 1 S(0.03)LS(0.195)S(0.195)S(0.557)PQAQPPRPAELS(0.023)DEEVAELFQR 46.902 0.014649 10629000.0 5509.3 4182.3 5805.6 6314.1 7979.4 12506.0 11948.0 11729.0 10016.0 11487.0 True False 5430.736371718119 4172.616141309748 5328.285978264077 6778.459977220136 7510.067380103993 11971.147532909883 12566.608977987016 12273.972158819637 8887.892606844165 13472.512644534621 0.4030975152894883 0.3097132844779662 0.3954931139311713 0.5031325749001948 0.5574362836579406 0.8885608682480031 0.9327591155080414 0.9110380878951192 0.6597056422470463 1.0 13.71773132030931 -6.513495690579594 1.7201293200407568 0.8824949583741286 0.3775697251813543 0.8519206968655676 0.09417219656168174 0.13107863574517756 0.7847447065304147 0.03651827954324522 0.0401939792390831 3.0655210978496473e-07 6.513495690579594 -0.5049252331927743 down SLSSS(ph)PVKK ddPTM_PC-9_AZD4547_30min_R2 1 SLSSSPVKK 9 1 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 SLS(0.174)S(0.174)S(0.651)PVKK 71.221 0.016303 151880000.0 666650.0 570480.0 669190.0 839960.0 694630.0 658910.0 525630.0 517550.0 547490.0 522110.0 True False 878630.8328185903 754876.5036555685 660316.1033590212 646320.199252636 598192.6146865814 617708.2535375461 572410.0517197656 437574.53961585666 576429.2036770122 503831.0878179168 1.7438996006060767 1.498272976613898 1.3105902341573208 1.282811273222216 1.1872880200333462 1.2260225072907454 1.1361149908372328 0.8684945216679343 1.1440921721871442 1.0 18.942580617662237 -1.5228787452813748 0.30540864504327914 0.9932157319209425 7.6270014081631405 0.8815422544659519 0.08042373774986028 17.308731823050408 0.2469815274878138 0.08173925312088764 63.11539187962758 0.02999999999992835 1.5228787452813748 6.633785676242198 SLSSS(ph)PVKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSSSPVKK 9 1 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 SLS(0.002)S(0.12)S(0.878)PVKK 86.014 0.0099819 0.0 20428.0 13373.0 18830.0 23315.0 23361.0 21808.0 25789.0 24571.0 20605.0 18458.0 True False 23886.056928608774 14700.583060921947 19278.97861317267 22008.73613824987 18783.57974834167 20664.350089210126 23346.079223808665 23926.037285126476 20906.309144169787 21804.289286552394 1.0954751432022274 0.6742060182621226 0.8841828486041419 1.0093764510739438 0.8614626003850665 0.9477194976474048 1.070710396335053 1.097308743737988 0.9588163534898416 1.0 14.412324345915918 -7.0721977032651795 4.237332741078665 1.0387774615627645 0.8970016350583744 0.2333428462722481 0.10751949683653692 0.3091197346536817 10.554238388653298 0.041402885797665705 0.03231156324982242 8.468418197718481e-08 7.0721977032651795 -0.14177582650439013 SLST(ph)DTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLSTDTSR 8 0 A0A087WVA8;Q8IWB9;Q8IWB9-2 A0A087WVA8 TEX2 Testis-expressed sequence 2 protein 1 SLS(0.245)T(0.652)DT(0.102)SR 92.051 0.020208 13489000.0 87674.0 105150.0 96965.0 92664.0 95691.0 97762.0 123170.0 83350.0 72381.0 68038.0 True False 102515.47655956772 115588.59708785932 99277.01334181007 87472.33650074156 76941.03547359126 92635.18861983478 111502.44592642243 81162.15081662503 73439.43519360111 80372.75081148853 1.275500409336669 1.4381565383890906 1.2352073599503994 1.088333242517789 0.9573025023624457 1.1525695921134684 1.3873165320414067 1.009821736809631 0.9137354943325348 1.0 16.29441883950463 -1.5228787452805783 0.23552370977842726 1.0001265078135062 3.2287036340724984 0.3802325848859398 0.1366059182158275 59.19631421050479 0.783938814737924 0.21117719937104484 51.24834069767965 0.02999999999998337 1.5228787452805783 2.228577126258992 SLST(ph)SGESLYHVLGLDK ddPTM_PC-9_AZD4547_30min_R2 1 SLSTSGESLYHVLGLDK 17 0 Q9H3Z4-2;Q9H3Z4 Q9H3Z4-2 DNAJC5 DnaJ homolog subfamily C member 5 1 S(0.005)LS(0.325)T(0.62)S(0.048)GES(0.002)LYHVLGLDK 109.67 0.0010831 67799000.0 28077.0 36324.0 81008.0 100510.0 87248.0 62969.0 67162.0 98311.0 74063.0 77555.0 True False 37004.90196212041 48065.02264546495 79933.78099031314 77338.9723640203 75135.12121010432 59031.53847567297 73139.28788996606 83119.29391203634 77977.81897738874 74839.82305590474 0.4944546960577132 0.6422385928085476 1.0680648046241807 1.0333933086165732 1.003945735600938 0.7887717536635127 0.9772776698754566 1.110629214742356 1.0419294941296153 1.0 16.19151852716248 -5.134045695861404 3.839922422598354 0.9992328735239397 0.5225298096029484 0.8196068880947042 0.08257876728057037 0.09820293279612519 2.4790087290015426 0.02369235321657609 0.07487093792870184 7.344365876951536e-06 5.134045695861404 -0.4767030639209914 SLST(ph)SGESLYHVLGLDK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSTSGESLYHVLGLDK 17 0 Q9H3Z4-2;Q9H3Z4 Q9H3Z4-2 DNAJC5 DnaJ homolog subfamily C member 5 1 SLS(0.087)T(0.647)S(0.262)GES(0.004)LYHVLGLDK 150.59 0.00012651 26064000.0 22244.0 26835.0 42414.0 25332.0 34638.0 36799.0 19418.0 23668.0 50318.0 16180.0 True False 21926.796480949997 26772.86520623747 38926.884642774654 27194.999785074757 32600.660940928137 35225.192552658766 20423.369026996294 24767.70168428196 44650.65696796971 18976.69144150518 1.1554593986279635 1.4108289260413838 2.0512998676700347 1.4330738247445374 1.717931760729643 1.8562346687903357 1.0762344473982957 1.3051643781334232 2.3529210613769744 1.0 14.211940862055332 -11.033119367061833 7.257017397915019 0.9998363947981365 1.5861239080601597 0.177681966071777 0.38382936036478094 0.0010022580699730309 6.763989277997856e-05 0.366613135790745 0.08889260064311555 9.265751165963979e-12 11.033119367061833 0.5862875132620232 SLST(ph)TNSSSSSGAPGPCGLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLSTTNSSSSSGAPGPCGLAR 21 0 W0Z7M9;A0A499FIJ6;Q969V6;E7ER32;A0A087X287;A0A087WU73;A0A494BZX7;B0QY83 W0Z7M9 mkl1;MKL1 MKL/myocardin-like protein 1 1 SLS(0.116)T(0.861)T(0.023)NSSSSSGAPGPCGLAR;SLS(0.322)T(0.675)T(0.003)NSSSSSGAPGPCGLAR 175.77 2.0985999999999997e-41 0.0 10383.3 10715.7 9175.099999999999 12404.0 13182.7 12146.4 12025.8 15500.4 14621.3 8954.9 True False 12140.987610476974 11779.483878405836 9393.869180760514 11709.04409431058 10599.644567803769 11509.421401484851 10886.629164747697 15093.530924031347 14835.108851718016 10578.352483050605 1.147720084949914 1.113546168676055 0.8880276201622176 1.106887307174879 1.0020127978139584 1.0880164392258693 1.029142220604866 1.4268319143472752 1.402402583529703 1.0 13.368827333124782 -7.748273572289491 24.99864045529019 1.3109629357228685 1.0509441245114968 0.3777965046092211 0.12871861465569373 187.91973527640394 356814.9088676358 0.05834452005152449 0.03342685166364828 1.785362578757642e-08 7.748273572289491 -0.2600188112113717 SLST(ph)VNSGTGVALTDTYSR ddPTM_PC-9_AZD4547_30min_R2 1 SLSTVNSGTGVALTDTYSR 19 0 Q8IZF6;Q8IZF6-3;Q8IZF6-2 Q8IZF6 GPR112 Probable G-protein coupled receptor 112 1 S(0.03)LS(0.171)T(0.775)VNS(0.024)GTGVALTDTYSR 66.538 0.023961 4960600.0 8205.5 9663.3 15419.0 25003.0 20050.0 15013.0 11727.0 21219.0 12969.0 15827.0 True False 10814.6783149973 12786.772748869103 15214.53398540437 19238.94464249923 17266.40358819221 14074.234736700251 12770.680281790765 17940.091114112354 13654.514863261755 15272.901547363877 0.7080958573234519 0.8372196147022317 0.9961783580036512 1.2596784299850279 1.1305254299352445 0.9215167591471499 0.8361659532857396 1.1746354193718245 0.8940354143524576 1.0 13.898686551070899 -5.117550887566964 2.732583162240837 1.0352883513517759 0.7222947286860979 0.41861692058970223 0.12413832892424302 0.29316345968435126 4.00575171203723 0.03499695543983938 0.1432514816311624 7.628674984868034e-06 5.117550887566964 -0.312993622665678 SLSVLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 SLSVLSPR 8 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6 A0A087WVP4 SMTN Smoothelin 1 SLSVLS(1)PR;SLSVLS(1)PR 112.11 0.0037351999999999997 27855000.0 61965.0 62047.0 92928.0 107516.0 99559.0 85481.0 78779.0 100554.0 79278.0 91725.0 True False 81668.58104793218 82102.47935478367 91695.71400192345 82729.84730564129 85736.95136343285 80135.85955690886 85790.17838485521 85015.68980104862 83468.47323075519 88513.73566891729 0.9226656228069597 0.9275676677107527 1.0359489779632423 0.9346554710456415 0.968628775133038 0.9053494234686287 0.9692301170718921 0.9604801916738325 0.9430002315456018 1.0 16.433613731285035 -10.901003129605781 3.1185097962785666 1.0005364456654984 0.9530717663716392 0.14991358217258433 0.03423396004852116 29851664.045448184 39496758.33879451 146092.49200664545 0.008455268078599767 1.2560209125449372e-11 10.901003129605781 -0.047464679293859224 SLSVLS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLSVLSPR 8 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6 A0A087WVP4 SMTN Smoothelin 1 SLS(0.008)VLS(0.991)PR;S(0.005)LS(0.011)VLS(0.984)PR;SLSVLS(1)PR;SLSVLS(1)PR 97.965 0.0056512 22543600.0 103484.0 112893.0 116814.0 131557.0 128687.0 112682.0 129018.0 124002.0 101525.0 93042.0 True False 121001.7972978341 124100.27095615504 119599.28877956209 124186.28780354866 103471.706137359 106772.75755467593 116796.48103056938 120747.07889097928 103009.61105857026 109909.77807993321 1.1009193122911602 1.129110376930264 1.088158768663713 1.1298929901690156 0.9414240292807065 0.9714582216427019 1.062657782327863 1.0986017895802183 0.9372197165538382 1.0 16.745960215227214 -6.243569847315429 24.827496258119517 1.0083401184641643 1.11153668549932 0.5525452496053688 0.04834080418648601 652.2217980503482 906180.7335462081 0.015010350058092313 0.019335104484536385 5.70729278749992e-07 6.243569847315429 0.10319656703515578 SLSVLS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 SLSVLSPR 8 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6 A0A087WVP4 SMTN Smoothelin 1 SLSVLS(1)PR;SLSVLS(1)PR;SLSVLS(1)PR 99.01299999999999 0.0053299 25398300.0 135860.0 111395.1 143507.0 127291.6 123071.0 105706.0 92882.0 96017.2 129415.0 96217.0 True False 133922.6114863271 111137.17149004442 131708.40841303935 136653.0488963294 115832.20574689563 101185.20079272117 97690.9754848835 100478.50964002198 114838.9198996343 112847.98024890656 1.1867524008044863 0.9848397042189976 1.1671312869094574 1.2109481144005985 1.0264446513921368 0.8966505255082011 0.8656865215434821 0.8903881967439604 1.0176426697787269 1.0 16.78402107186809 -6.535788724053042 4.440534149357999 0.9245155204106714 1.1286299962282713 0.6342767594731307 0.07237057388740208 0.13111570808519543 6.416049694314572 0.024530721946216937 0.025617331291009526 2.91213347067887e-07 6.535788724053042 0.2041144758175999 SLSVS(ph)SDFLGK ddPTM_PC-9_Lapatinib_30min_R1 1 SLSVSSDFLGK 11 0 A0A2R8Y4C6;A0A2R8YCU9;A0A2U3TZV9;A0A2R8Y7B1;H7C2C6;A0A2R8Y820;A0A2R8Y4Z5;A0A2R8Y885;A0A2R8Y7D4;A0A2R8YDS8;H0Y470;H0Y7U8;A0A2R8Y5D7;H0Y7K3;Q3V6T2-5;Q3V6T2-4;Q3V6T2-2;Q3V6T2-3;Q3V6T2 A0A2R8Y4C6 CCDC88A Girdin 1 SLS(0.012)VS(0.762)S(0.226)DFLGK 95.094 0.016123 0.0 14359.0 13473.0 13216.0 10563.0 10348.0 8723.9 12716.0 12109.0 12223.0 9218.8 True False 14154.238026881894 13441.804096278645 12129.431495235305 11339.838257135038 9739.35098495076 8350.79913340417 13374.372260134152 12671.628346077834 10846.317026103865 10812.257296721138 1.3090918610653324 1.2432005387399474 1.1218223135435008 1.0487947101086736 0.9007694432044508 0.772345580042438 1.236963928354719 1.1719688126475272 1.0031501034842238 1.0 13.400380128414726 -5.358748989652325 1.8894217282934942 1.0200357047532382 1.3020014727595484 0.4194399602090312 0.12143654037701451 0.423739910725942 2.7800819327157984 0.03905717618251108 0.13647404334059104 4.377750540757462e-06 5.358748989652325 0.2819657680063101 SLSYS(ph)PVER ddPTM_PC-9_AZD4547_30min_R2 2 SLSYSPVER 9 0 Q9UQ35;Q9UQ35-2;I3L4U6 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.001)LS(0.348)YS(0.652)PVER;SLS(0.03)YS(0.969)PVER 98.898 0.0043143 81689000.0 75190.0 82472.0 126450.0 171374.0 151427.0 132402.0 104121.0 150982.0 102430.0 114589.0 True False 99098.85595084364 109129.46117213918 124773.19037903781 131866.3720019064 130403.97487028339 124122.88200949792 113387.56729089594 127651.20112120791 107844.24068501043 110577.273988177 0.8961955054294373 0.9869067778231483 1.1283800538651247 1.1925268841046457 1.1793017694054049 1.1224990229255356 1.0254147457371703 1.1544071988504299 0.9752839511719308 1.0 16.754695385565377 -5.043383955290567 3.1195444113132718 1.1070843542338737 0.9026262270969093 0.4473818263595445 0.07171521514777034 0.2228015503923012 4.133835452228969 0.01893908367354428 0.08127625854527246 9.049322058716807e-06 5.043383955290567 -0.20445812713696443 SLSYS(ph)PVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLSYSPVER 9 0 Q9UQ35;Q9UQ35-2;I3L4U6 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.004)LS(0.459)YS(0.537)PVER;SLS(0.258)YS(0.742)PVER;SLS(0.48)YS(0.52)PVER;S(0.006)LS(0.111)YS(0.883)PVER 126.03 0.0014077 153106000.0 491634.0 476590.0 601692.0 520358.0 663850.0 612302.0 579130.0 569742.0 578038.0 414242.0 True False 574857.9259858832 523902.7055264182 616038.6192096173 491204.0282833981 533773.3579870984 580191.8052239328 524270.61386189255 554786.8761915478 586490.7122095409 489340.7954621321 1.1747598633034244 1.070629529327605 1.2589153099892931 1.0038076384363301 1.0908008548173556 1.1856599952513693 1.071381374133691 1.1337433570557074 1.1985322246751586 1.0 18.900480037112743 -11.957064725456107 2.0498987025107596 2.3118174493057378e-05 1.128812606521254 0.234492951259212 0.07135081885350064 1673764.6824952678 165655.6631522091 7762871.921448216 0.017444661204870312 1.1039140848451182e-12 11.957064725456107 1.128789488346761 SLSYS(ph)PVER ddPTM_PC-9_Lapatinib_30min_R1 4 SLSYSPVER 9 0 Q9UQ35;Q9UQ35-2;I3L4U6 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.001)LS(0.183)YS(0.816)PVER;SLS(0.189)YS(0.811)PVER;SLS(0.33)YS(0.669)PVER;SLS(0.328)YS(0.672)PVER 130.01 0.0012797000000000002 174262000.0 212869.0 183845.0 253495.0 198209.0 225165.0 213793.0 181147.0 186591.0 257879.0 170378.0 True False 209833.44902460664 183419.31819790354 232653.6196189978 212785.95106584087 211921.23739142242 204649.57176582448 190525.90530092182 195260.69904393508 228833.95143374277 199827.61028558528 1.0500723534886967 0.9178877630361906 1.164271640372914 1.064847599196808 1.060520300916142 1.0241306067432216 0.9534513525364695 0.9771457445989402 1.1451568234574934 1.0 17.608396409269226 -6.896443568108899 5.771649074297692 1.0133023451098562 1.0508684388301321 0.04245030995450483 0.07300831210418644 0.7398512130990936 35.499458400544164 0.026528391508870385 0.023370930625366965 1.2692770626160078e-07 6.896443568108899 0.03756609372027597 SLT(ph)AHSLLPLAEK ddPTM_PC-9_AZD4547_30min_R2 1 SLTAHSLLPLAEK 13 0 F2Z2E2;Q86VI3 F2Z2E2 IQGAP3 Ras GTPase-activating-like protein IQGAP3 1 S(0.414)LT(0.583)AHS(0.003)LLPLAEK 109.55 0.0016236 3999200.0 48243.0 49539.0 59501.0 81351.0 73471.0 61788.0 42890.0 54616.0 40496.0 48838.0 True False 63583.27048326296 65551.51296205503 58711.97786273727 62596.78381042097 63270.8198517741 57924.38659236901 46707.12691106043 46176.35215082518 42636.53588577746 47128.19648513029 1.349155605887115 1.3909191917144037 1.2457930122843095 1.3282236215037695 1.3425258034590197 1.2290813337328768 0.9910654426548507 0.979803081694301 0.9046927119146174 1.0 15.524302852505864 -7.18304206916376 2.399676133457257 0.9563969330852119 1.3299691417916704 0.9460147503320221 0.04104348401166537 0.06411979083277929 0.7226242168156062 0.019061029940545635 0.013345977715048626 6.560817100135503e-08 7.18304206916376 0.37357220870645846 SLT(ph)AHSLLPLAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLTAHSLLPLAEK 13 0 F2Z2E2;Q86VI3 F2Z2E2 IQGAP3 Ras GTPase-activating-like protein IQGAP3 1 S(0.1)LT(0.9)AHS(0.001)LLPLAEK 106.76 0.0022714000000000002 2271600.0 48269.0 38951.0 43728.0 45699.0 53039.0 48318.0 43672.0 37091.0 39770.0 33058.0 True False 56439.98834379368 42817.79786180888 44770.6413593635 43138.63318815703 42646.38869364727 45784.11902102229 39535.0720021006 36117.400551163024 40351.56101255194 39051.15371301597 1.4452835057977278 1.0964541067460822 1.1464614256567072 1.104669877494008 1.0920647570889304 1.172413992106005 1.0123919076153527 0.9248740976153258 1.0333000993797152 1.0 15.253077551001454 -1.5228787452803376 0.7586370157169998 1.0429762297319103 69.92238838108682 0.7247206322760025 0.07028154148837909 232.15536355210045 0.9663188781910922 0.02813096821333223 27357.16199007333 0.029999999999999995 1.5228787452803376 68.87941215135491 SLT(ph)AHSLLPLAEK ddPTM_PC-9_Lapatinib_30min_R1 1 SLTAHSLLPLAEK 13 0 F2Z2E2;Q86VI3 F2Z2E2 IQGAP3 Ras GTPase-activating-like protein IQGAP3 1 S(0.42)LT(0.566)AHS(0.014)LLPLAEK 83.292 0.020040000000000002 3410800.0 36041.0 32868.0 42106.0 31572.0 40749.0 47097.0 34278.0 36244.0 43088.0 28164.0 True False 35527.04873089009 32791.896165403894 38644.20721386026 33893.910201104554 38352.22393561641 45082.77109846929 36052.747116457875 37928.02855522713 38234.97570324497 33032.10987382895 1.0755307144045878 0.9927278726868314 1.1698982402718914 1.0260897753902907 1.1610588630913503 1.3648165760730886 1.0914454830214206 1.1482169531434374 1.1575093401326508 1.0 15.01158150198232 -6.318821733501149 8.62532566469333 1.1688773695757402 1.0683088086793107 0.15781904484363585 0.09559466115853057 0.6385034789171036 91.10844107582838 0.029403428805633215 0.033393196271437726 4.79930407060472e-07 6.318821733501149 -0.10056856089642952 SLT(ph)FTGGAK ddPTM_PC-9_Lapatinib_30min_R1 2 SLTFTGGAK 9 0 F5H8C5;F5H0S5;F5H7J1;Q8NHQ8-2;Q8NHQ8 F5H8C5 RASSF8 Ras association domain-containing protein 8 1 SLT(0.957)FT(0.043)GGAK;S(0.037)LT(0.961)FT(0.002)GGAK 113.44 0.0051365000000000004 21059000.0 192864.0 147272.0 181899.0 179224.0 183446.0 159791.0 124570.0 116853.0 169107.0 127238.0 True False 190113.72399307418 146931.00073236445 166943.96637044527 192404.73083373785 172656.06694871263 152957.11142101412 131019.6250743089 122282.41697284924 150060.38888434452 149230.91876602176 1.273956667727499 0.9845881935682288 1.118695560885715 1.2893087600392519 1.1569724851685663 1.0249693072039223 0.8779656800192578 0.8194174369761477 1.0055582993469556 1.0 17.187186949233407 -6.958692368439384 3.154323791990294 0.9124067272013717 1.1588759652318414 0.5872637503307395 0.09430333628894769 0.18139669782272486 3.708349559548481 0.03749641796425464 0.03129921310149929 1.0997845936330627e-07 6.958692368439384 0.24646923803046972 SLT(ph)LDAAPDHNPPCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLTLDAAPDHNPPCR 15 0 B7Z5R6;Q14596-2;Q14596 B7Z5R6 NBR1 Next to BRCA1 gene 1 protein 1 S(0.061)LT(0.939)LDAAPDHNPPCR 89.344 0.0095706 5265100.0 12796.0 15190.0 17320.0 19476.0 17648.0 14686.0 16705.0 12991.0 16488.0 13999.0 True False 14962.11006747983 16697.96281278728 17732.974486465788 18384.82286204394 14190.001087228016 13915.840306774566 15122.581466273377 12650.000015102283 16729.105807768567 16536.90788397697 0.9047707208901489 1.009739119909252 1.072327100742196 1.1117448915499772 0.8580806754675744 0.84150195456177 0.914474554274202 0.7649555832235837 1.0116223616373785 1.0 14.013401880232191 -6.276590325662326 24.89277144369573 0.8846418682280763 1.0269865537683514 0.3408105161245466 0.08466807125624792 772.9973311608026 1270019.9695945317 0.025826936062591767 0.029388301540179334 5.289439746659082e-07 6.276590325662326 0.14234468554027502 SLT(ph)NDWEDHLAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLTNDWEDHLAVK 13 0 P07900;P07900-2;P08238 P07900;P08238 HSP90AA1;HSP90AB1 Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta 1 S(0.353)LT(0.647)NDWEDHLAVK 97.073 0.0065077 3068200.0 14955.0 24101.0 16667.0 19704.0 15814.0 12564.0 20149.0 16291.0 17052.0 12594.0 True False 17486.586125286085 26493.588002039913 17064.404489949484 18600.048761229915 12715.360221748862 11905.121722342074 18240.340853872633 15863.3785117413 17301.353240785396 14877.192505950854 1.1753955672948022 1.7808190618923911 1.1470177913691544 1.2502391666834938 0.8546881554878542 0.8002263678163769 1.2260606862871826 1.0662884482671025 1.16294477159349 1.0 13.860814678852108 -5.6220287379436 2.238659254314029 1.0327853183886964 1.4718650620546898 0.40413829855897576 0.19733314997160045 0.27857066702823874 2.806854537707701 0.05672057182507857 0.12320282307378472 2.3876532829419313e-06 5.6220287379436 0.43907974366599345 SLT(ph)PAVPVESKPDKPSGK ddPTM_PC-9_AZD4547_30min_R2 1 SLTPAVPVESKPDKPSGK 18 2 H0Y944;P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;F8W7E0;P20810-2;E9PCH5;E9PSG1;P20810-3;H0YA91;E7EQK6 H0Y944;P20810-6 CAST Calpastatin 1 S(0.172)LT(0.827)PAVPVES(0.001)KPDKPSGK 54.511 0.019931 20124000.0 30932.0 40573.0 46838.0 58242.0 55672.0 60467.0 51490.0 66337.0 57644.0 77590.0 True False 40767.73257443134 53687.428801741225 46216.89751659446 44815.20672993003 47942.903768670185 56685.98893119658 56072.51025065291 56086.140922610466 60690.944157441576 74873.5977165578 0.5444874270468751 0.7170408587147217 0.6172656173348793 0.5985448555521922 0.640317885486995 0.7570891563911167 0.7488956315805945 0.7490776806923409 0.8105787087618495 1.0 16.192169457934178 -8.59532417458938 0.30008042585597755 1.0534542030377823 0.5828259822295776 0.8571607480215709 0.04661115689022338 0.8170853533134176 0.21144457856044976 0.13418907010422976 0.07212602362587132 2.5390767306611042e-09 8.59532417458938 -0.47062822080820466 SLT(ph)PAVPVESKPDKPSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLTPAVPVESKPDKPSGK 18 2 H0Y944;P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;F8W7E0;P20810-2;E9PCH5;E9PSG1;P20810-3;H0YA91;E7EQK6 H0Y944;P20810-6 CAST Calpastatin 1 S(0.05)LT(0.95)PAVPVESKPDKPSGK 62.077 0.010259 8043800.0 31709.0 51685.0 32177.0 46558.0 54340.0 47995.0 40509.0 33002.0 35005.0 39661.0 True False 37076.70741870255 56815.94522573472 32944.22171195204 43949.50620307258 43692.467082953925 45478.05770963129 36671.69426023751 32135.732468509384 35516.88190204626 46851.22534369677 0.7913711359032948 1.212688564897451 0.7031667041849154 0.9380652454799759 0.9325789616478447 0.9706908917751449 0.7827264706785565 0.6859101812762477 0.7580779721660919 1.0 15.515799160073337 -7.273005378612302 23.080605639248127 0.7805044586322674 0.9287356335353132 0.1273516271035665 0.14487095311502188 445.51562411971423 889044.1717130542 0.057394959374766776 0.03913907383731435 5.3332829032917176e-08 7.273005378612302 0.14823117490304583 SLT(ph)PPPSSTESK ddPTM_PC-9_AZD4547_30min_R2 3 SLTPPPSSTESK 12 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 S(0.001)LT(0.997)PPPS(0.002)S(0.001)TESK;S(0.092)LT(0.893)PPPS(0.005)S(0.005)T(0.005)ESK;S(0.002)LT(0.833)PPPS(0.018)S(0.141)T(0.005)ES(0.001)K 118.87 0.0013817 90857700.0 99354.0 83138.0 114038.0 154879.0 140223.0 126425.0 104197.0 133923.0 100712.0 111197.0 True False 130946.5053084204 110010.73264779925 112525.78160889448 119174.03940669679 120755.45687516585 118519.62476435928 113470.33114366463 113228.27759438544 106035.43071237703 107304.0268757329 1.2203316978967385 1.0252246430155034 1.0486631758862957 1.1106203828185344 1.125358109952489 1.1045216867920062 1.0574657302942865 1.0552099570830955 0.9881775530677426 1.0 16.71134469260617 -7.89628019174949 1.4275403535006395 0.9933302993905887 1.099999862200347 0.42526913334229766 0.04960277547307001 0.4463515145708216 1.6471599140703128 0.042723580984456035 0.01517416704527083 1.2697546392008601e-08 7.89628019174949 0.10666956280975837 SLT(ph)PPPSSTESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLTPPPSSTESK 12 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 S(0.002)LT(0.998)PPPSSTESK;S(0.04)LT(0.96)PPPSSTESK 136.38 0.00015457 62145000.0 123859.0 131391.0 127194.0 171025.0 182550.0 152598.0 146065.0 128330.0 137542.0 120876.0 True False 144825.88237324017 144434.63014713174 130226.78734593137 161443.02372053103 146780.63794614008 144595.4922465741 132228.66578097688 124961.47347687432 139553.29154610075 142789.86194611082 1.014258858432805 1.0115188023757713 0.912017040783184 1.1306336564808779 1.0279485948486693 1.0126453676462321 0.9260367926602537 0.8751424770200775 0.9773333319613996 1.0 17.12353402635786 -7.240347487745255 7.568202727639765 0.9341751896850661 1.0187376298377882 0.270407862963695 0.05817842713834253 0.24495216699003353 69.60895342581746 0.022894003522562545 0.017236539171093652 5.749797004226292e-08 7.240347487745255 0.08456244015272207 SLT(ph)PPPSSTESK ddPTM_PC-9_Lapatinib_30min_R1 5 SLTPPPSSTESK 12 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 S(0.068)LT(0.929)PPPS(0.001)S(0.002)TESK;S(0.006)LT(0.938)PPPS(0.024)S(0.024)T(0.006)ES(0.002)K;S(0.005)LT(0.995)PPPSSTESK;S(0.454)LT(0.546)PPPSSTESK;S(0.001)LT(0.999)PPPSSTESK 130.15 0.00037728 166618100.0 295695.0 250735.0 267334.0 244345.0 272086.0 256507.0 226395.0 245306.0 251880.0 204739.0 True False 291478.3350761782 250154.43851261248 245354.83045908282 262314.94641102495 256082.43642165774 245536.79355702194 238116.62534075728 256703.81229358073 223510.62198601343 240127.86335243046 1.2138463692086485 1.0417551508608822 1.0217674327072193 1.092396953643114 1.0664419898902406 1.0225252085662917 0.9916243038871281 1.0690296773965882 0.9307983624456431 1.0 17.87344329153312 -4.761229783913398 4.922692419178576 1.0295870926785424 1.2262133141680356 0.6248053501418591 0.043642213528263134 0.11875114006224884 7.361962910486035 0.010757375400663691 0.08135081487643127 1.732886889877671e-05 4.761229783913398 0.19662622148949316 SLT(ph)QPITTEEVVIAATLQASAHQK ddPTM_PC-9_AZD4547_30min_R2 3 SLTQPITTEEVVIAATLQASAHQK 24 0 O95425-2;O95425-4 O95425-2 SVIL Supervillin 1 S(0.172)LT(0.823)QPIT(0.005)TEEVVIAATLQASAHQK;S(0.148)LT(0.805)QPIT(0.044)T(0.002)EEVVIAATLQASAHQK;S(0.208)LT(0.712)QPIT(0.078)T(0.001)EEVVIAATLQASAHQK 197.61 1.3617e-24 95711800.0 16153.58 16476.02 43327.1 75865.2 46145.0 46495.5 33502.7 48641.1 35502.3 48625.4 True False 21290.08242466322 21801.57125886833 42752.554344575765 58375.65024565581 39738.563270679755 43588.1290348529 36484.37539667022 41124.73565628212 37378.87909861805 46923.039546419895 0.4537234294807655 0.4646240198762174 0.9111207363768844 1.2440722257113397 0.8468880885554589 0.928928080026277 0.7775364884573827 0.876429490796272 0.7965996972902826 1.0 15.518008849789588 -5.262463928126082 7.1231427352448575 0.9225632697261723 0.45705274869473683 0.6904342314378595 0.12417712125923279 0.0690396119004025 26.319499821700624 0.034065373878867995 0.08011513916234728 5.464319338461689e-06 5.262463928126082 -0.4655105210314355 SLT(ph)QPITTEEVVIAATLQASAHQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLTQPITTEEVVIAATLQASAHQK 24 0 O95425-2;O95425-4 O95425-2 SVIL Supervillin 1 S(0.203)LT(0.788)QPIT(0.008)T(0.001)EEVVIAATLQASAHQK;S(0.238)LT(0.741)QPIT(0.015)T(0.006)EEVVIAATLQASAHQK 177.44 3.7295e-14 35942700.0 9675.8 11357.5 20143.3 20240.0 25044.3 21602.1 17874.4 15614.9 20180.8 12806.0 True False 11313.721834238924 12484.997540897395 20623.59266589065 19106.018418965352 20137.049197011816 20469.247847676357 16181.207432550544 15205.025420354139 20475.90602167734 15127.626427759777 0.7478847979401322 0.8253110691566883 1.363306581133281 1.2629885137766936 1.3311440028727544 1.3531037367577043 1.0696461543271194 1.0051164003132926 1.3535438701806692 1.0 13.884898021464242 -5.1852034339921484 6.081577758640664 1.2223840303819504 0.7746266858531715 0.6104282049385135 0.13778117140464008 0.15223790504867865 9.569370957223382 0.03625696323545127 0.0988216024665263 6.528246822148422e-06 5.1852034339921484 -0.4477573445287789 SLT(ph)QPITTEEVVIAATLQASAHQK ddPTM_PC-9_Lapatinib_30min_R1 2 SLTQPITTEEVVIAATLQASAHQK 24 0 O95425-2;O95425-4 O95425-2 SVIL Supervillin 1 S(0.139)LT(0.858)QPIT(0.003)TEEVVIAATLQASAHQK;S(0.199)LT(0.787)QPIT(0.014)T(0.001)EEVVIAATLQASAHQK 213.71 2.4873e-37 33251300.0 44239.8 24649.9 59837.0 34524.8 35014.9 50451.4 31197.6 30242.6 51246.0 24149.0 True False 43608.9323394143 24592.82467103535 54917.432837499575 37063.868963356595 32955.39242394207 48293.71122995757 32812.85907697082 31647.781602039297 45474.135835696514 28323.122473480144 1.539693668318059 0.8682949662087013 1.938961104621164 1.3086081521576831 1.1635508215875303 1.7050984147378712 1.1585184192772022 1.1173832133682344 1.6055481127928397 1.0 14.789692703186537 -12.707449103356899 0.3608718028778307 5.5462885410826734e-08 1.3793969068933363 0.11726968684802541 0.3051921134342132 256.7222268068265 7.072105434952288 195.46724409694232 0.2162459664369828 1.961331017944152e-13 12.707449103356899 1.3793968514304509 SLTDPSQESHTEAIS(ph)DAETSSSDISFSGIATR ddPTM_PC-9_AZD4547_30min_R2 1 SLTDPSQESHTEAISDAETSSSDISFSGIATR 32 0 Q5QJE6;J3KP30 Q5QJE6 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 SLTDPSQESHT(0.046)EAIS(0.949)DAET(0.003)S(0.001)S(0.001)SDISFSGIATR 124.57 8.4552e-18 7247400.0 35840.0 32724.0 62641.0 82365.0 66877.0 60287.0 43154.0 67747.0 47807.0 55146.0 True False 47236.374481689505 43301.39304730193 61810.33941109768 63377.02177656479 57592.282931048954 56517.2443596515 46994.6223996247 57278.25782118707 50333.98042007515 53215.35532513607 0.8876455713409017 0.8137010977891316 1.161513233040498 1.190953652180706 1.0822493353501195 1.0620476742914051 0.8831026705073407 1.076348310957005 0.9458544458181996 1.0 15.699554975933413 -5.2487550744429186 24.990578170138065 1.0536039155759536 0.8506733099551262 0.4486749513170183 0.08843440848645041 728.3151124009497 1434918.1782294675 0.024217175103794224 0.06311215365905323 5.639556156600856e-06 5.2487550744429186 -0.20293060562082732 SLTDPSQESHTEAIS(ph)DAETSSSDISFSGIATR ddPTM_PC-9_Lapatinib_30min_R1 3 SLTDPSQESHTEAISDAETSSSDISFSGIATR 32 0 Q5QJE6;J3KP30 Q5QJE6 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 SLTDPSQESHT(0.002)EAIS(0.746)DAET(0.158)S(0.062)S(0.024)S(0.005)DIS(0.001)FSGIATR;SLTDPS(0.001)QES(0.004)HT(0.024)EAIS(0.694)DAET(0.055)S(0.063)S(0.072)S(0.072)DIS(0.009)FS(0.003)GIAT(0.003)R;SLTDPSQESHT(0.001)EAIS(0.99)DAET(0.006)S(0.002)S(0.001)S(0.001)DISFSGIATR 127.92 2.5613000000000003e-16 16675300.0 87024.9 60899.0 87275.1 69547.0 83673.8 80228.6 69796.1 79915.5 99602.0 65009.6 True False 85783.90896758805 60757.99210712338 80099.67816962853 74661.71838199084 78752.27159302015 76797.40980000113 73409.80054305981 83628.66587587624 88383.77390444209 76246.42274015304 1.1250876550620434 0.7968635107536249 1.0505368683670229 0.979216016945964 1.0328651333769063 1.0072263988269436 0.9627966520244444 1.0968208457579944 1.159185844110392 1.0 16.218382031655203 -7.770217373755982 24.70481085368216 1.0960025666983109 0.989634024174299 0.18619692466988214 0.08685263783832109 238.0291711394544 669896.6426408483 0.04378868927814836 0.021542334735981127 1.6973938575704234e-08 7.770217373755982 -0.10636854252401184 SLTDPSQESHTEAISDAET(ph)SSSDISFSGIATR ddPTM_PC-9_AZD4547_30min_R2 1 SLTDPSQESHTEAISDAETSSSDISFSGIATR 32 0 Q5QJE6;J3KP30 Q5QJE6 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 SLTDPS(0.001)QES(0.002)HT(0.007)EAIS(0.246)DAET(0.466)S(0.181)S(0.072)S(0.021)DIS(0.004)FS(0.001)GIATR 73.87 4.2448e-06 9324100.0 8977.4 9798.8 18552.0 21242.0 17425.0 12755.0 11552.0 22207.0 16636.0 15611.0 True False 11832.026458479893 12966.070474022179 18305.98835833855 16344.985085628474 15005.839527393982 11957.427833651622 12580.105620810684 18775.41841609373 17515.34499693287 15064.463641618582 0.7854263344492108 0.8607057498018599 1.215176908639788 1.085002790306599 0.9961084499508739 0.7937506517402216 0.8350848672803481 1.2463383272553359 1.1626929052119213 1.0 13.878861687373817 -7.764946509709584 24.99995726492076 1.1533867133087612 0.9486350688955192 0.2916050067285796 0.13978558590039916 125.70506251651264 896037.6128613672 0.07955573065458729 0.040620992021769206 1.718119987998827e-08 7.764946509709584 -0.204751644413242 SLTEISTDFDRS(ph)SPPLQPPPVNSLTTENR ddPTM_PC-9_Lapatinib_30min_R1 1 SLTEISTDFDRSSPPLQPPPVNSLTTENR 29 1 J3KRR7;Q9NQC7-2;Q9NQC7 J3KRR7 CYLD Ubiquitin carboxyl-terminal hydrolase CYLD 1 SLTEIS(0.003)T(0.012)DFDRS(0.603)S(0.381)PPLQPPPVNSLTTENR 108.49 8.6123e-12 15040000.0 15020.0 9921.1 13353.0 10269.0 11822.0 14736.0 9440.0 10141.0 12686.0 9909.1 True False 14805.81204566934 9898.128302500569 12255.167884070588 11024.216516379787 11126.653202946265 14105.775631293787 9928.757009725261 10612.187881540629 11257.16909049771 11621.874731954204 1.273960732424773 0.8516808630956747 1.054491479793286 0.948574715408766 0.9573888429853462 1.213726352815534 0.8543162991101826 0.9131218608270271 0.968619035235878 1.0 13.504555189112533 SLTEISTDFDRSS(ph)PPLQPPPVNSLTTENR ddPTM_PC-9_AZD4547_30min_R2 2 SLTEISTDFDRSSPPLQPPPVNSLTTENR 29 1 J3KRR7;Q9NQC7-2;Q9NQC7 J3KRR7 CYLD Ubiquitin carboxyl-terminal hydrolase CYLD 1 SLTEIST(0.001)DFDRS(0.188)S(0.81)PPLQPPPVNSLTTENR;SLTEISTDFDRS(0.19)S(0.81)PPLQPPPVNSLTTENR 102.72 2.2728e-11 33029000.0 49262.3 40593.4 65701.5 88276.4 76180.0 66043.5 55637.1 72649.3 52937.4 59078.9 True False 64926.686680505896 53714.422702797514 64830.25518140253 67925.6398367844 65603.7219625177 61913.78950464694 60588.69411665569 61423.019999834265 55735.562890155954 57010.56569321764 1.1388535772454194 0.9421836470075184 1.1371621100948865 1.1914570397757915 1.150729187911257 1.0860055281298957 1.0627625490105201 1.0773971324957674 0.9776356752900389 1.0 15.798941696381776 -8.01553218261514 1.4349829884419771 0.9876791845229055 1.1053872044980795 0.32032059119972756 0.0639874386342158 0.5637134683985665 2.081777544639681 0.06141758686502916 0.020504985936933926 9.648678093545575e-09 8.01553218261514 0.117708019975174 SLTEISTDFDRSS(ph)PPLQPPPVNSLTTENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLTEISTDFDRSSPPLQPPPVNSLTTENR 29 1 J3KRR7;Q9NQC7-2;Q9NQC7 J3KRR7 CYLD Ubiquitin carboxyl-terminal hydrolase CYLD 1 SLTEIS(0.005)T(0.005)DFDRS(0.197)S(0.792)PPLQPPPVNSLTTENR;SLTEISTDFDRS(0.176)S(0.823)PPLQPPPVNSLTTENR 117.53 1.2569000000000002e-13 26877000.0 27561.0 26031.0 27774.0 37024.0 39880.0 36563.0 31869.0 27843.0 32111.0 28767.0 True False 32226.532945436993 28615.185647114275 28436.237493481574 34949.665313427526 32065.80028097536 34645.571914517124 28850.137608420595 27112.150752097048 32580.562626956384 33982.2293805533 0.9483348659837774 0.8420632244772507 0.8367972911675572 1.0284688777195958 0.9436049625197741 1.0195202770994016 0.8489771899700731 0.7978331983013531 0.9587529488456977 1.0 15.052492882182356 -5.689134903109899 24.999999962883518 0.9334052400515079 0.8723650845033482 0.1369240145530205 0.07422745659413478 102.49894948011827 35437.0760585197 0.02139907165332245 0.037064270996594144 2.045809056757266e-06 5.689134903109899 -0.06104015554815978 SLTEISTDFDRSS(ph)PPLQPPPVNSLTTENR ddPTM_PC-9_Lapatinib_30min_R1 1 SLTEISTDFDRSSPPLQPPPVNSLTTENR 29 1 J3KRR7;Q9NQC7-2;Q9NQC7 J3KRR7 CYLD Ubiquitin carboxyl-terminal hydrolase CYLD 1 SLTEIST(0.001)DFDRS(0.392)S(0.607)PPLQPPPVNSLTTENR 101.76 2.8571e-11 14456000.0 20066.0 16195.0 19341.0 12457.0 10846.0 14718.0 13497.0 8660.4 15361.0 13210.0 True False 19779.855160346284 16157.50147251784 17750.857638419035 13373.129335333813 10208.059604056432 14088.545449333738 14195.808618671796 9062.793800344576 13630.882421498922 15493.330898781434 1.276668993231274 1.0428681590857034 1.1457095801016655 0.8631539223360694 0.658867978147895 0.9093296684473328 0.9162528517214016 0.584948056654323 0.8797903117509098 1.0 13.919359720872183 -5.8004589969718445 4.4643344331381245 0.8090131566812894 1.147092242651385 0.5733780523152807 0.12807294410470096 0.13776243776778271 6.040106384989518 0.03550998359750516 0.05650571776595005 1.5832190360481423e-06 5.8004589969718445 0.3380790859700956 SLTGTARYMSINT(ph)HLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLTGTARYMSINTHLGK 17 1 Q9Y6M4-6;Q9Y6M4-4;Q9Y6M4-3;Q9Y6M4-5;A0A087WWF5;A0A0U1RQY7;Q8IXA3;A0A0U1RQT7;U3KQA5;K7ESB6;Q9HCP0-2;U3KQB3;A0A087WXD7;P78368;Q9HCP0;Q9Y6M4;Q9Y6M4-2 Q9Y6M4-6 CSNK1G3;CSNK1G2;hCG_2004507;CSNK1G1 Casein kinase I isoform gamma-3;Casein kinase I isoform gamma-1;Casein kinase I isoform gamma-2 1 SLT(0.001)GT(0.001)ARY(0.001)MS(0.192)INT(0.804)HLGK 52.527 0.043537 11295000.0 8814.2 6062.9 9676.7 17691.0 13241.0 21423.0 17427.0 18194.0 19411.0 14260.0 True False 10306.26997161462 6664.784643689795 9907.429227089116 16699.83062499585 10646.521101313818 20299.540166963885 15776.188399446039 17716.426778136465 19694.84915299585 16845.22511790211 0.611821444918639 0.3956482977842104 0.588144661632339 0.9913688008388951 0.6320201141152648 1.2050619700766558 0.9365377006852842 1.0517180182595773 1.1691650907096116 1.0 14.040052088170048 -5.969573115164985 0.8354639663452343 1.069987525220061 0.44850943363552626 0.6632604426381477 0.15322180654437945 0.4229330715597386 0.585072127402009 0.07097379744449137 0.17572703416905397 1.0725730607887071e-06 5.969573115164985 -0.6214780915845348 SLTIAEFK ddPTM_PC-9_Lapatinib_30min_R1 2 SLTIAEFK 8 0 K7EK42;A0A494C0X0;Q99426;K7EL99 K7EK42 TBCB Tubulin-folding cofactor B 0 ; 124.98 0.015649 5131700.0 50147.0 53017.0 56531.0 52561.0 52370.0 48631.0 55150.0 49686.0 51413.0 48857.0 False True 49431.894584166505 52894.242393854765 51883.239395970544 56426.51127835601 49289.69956338146 46551.16549439794 58005.39714897755 51994.59294766072 45622.32653710852 57301.86735213962 0.8626576561700959 0.9230806051886845 0.9054371487953482 0.9847237775271049 0.8601761485446776 0.8123847903302185 1.0122776068101673 0.9073804284271596 0.796175214618115 1.0 15.806294533815654 -11.04168281007509 5.433589393515247 1.0002429913284545 0.8999511951428845 0.1864901491268336 0.06467925792135462 0.00019056869227569985 1.68765938668996e-05 0.06268416657992482 0.015166447403022872 9.08483805253241e-12 11.04168281007509 -0.10029179618557005 SLTLGPSLS(ph)LGSISGVSVK ddPTM_PC-9_AZD4547_30min_R2 2 SLTLGPSLSLGSISGVSVK 19 0 O75128-3;O75128;O75128-7;A0A0J9YWK3;A0A3B3IU00;H7C1N2;J3KR05;O75128-5;O75128-4;O75128-2 O75128-3 COBL Protein cordon-bleu 1 SLTLGPS(0.003)LS(0.973)LGS(0.022)IS(0.001)GVS(0.001)VK;SLTLGPSLS(0.496)LGS(0.496)IS(0.006)GVS(0.002)VK 106.44 0.0002214 15803800.0 38730.0 40370.0 56616.0 67415.0 72584.0 63889.0 47623.0 73803.0 60824.0 61362.0 True False 51045.33436595516 53418.81302162264 55865.23484776275 51873.51330136725 62506.964491039515 59894.01073023667 51861.35474202455 62398.442174222735 64039.032465342934 59213.735057139216 0.8620522640008804 0.9021355091023278 0.9434506165479128 0.876038528076486 1.0556159720497693 1.0114884776723003 0.875833194646143 1.0537832500180977 1.0814894956980416 1.0 15.853644237844025 -5.314217563303651 0.40380746718463245 1.0304726284371901 0.7928095259884876 0.43694691328948654 0.05998960911361614 3.850341570217564 0.6811892104575219 0.054822895070153366 0.42491874822853243 4.8504545187963905e-06 5.314217563303651 -0.23766310244870248 SLTLGPSLS(ph)LGSISGVSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLTLGPSLSLGSISGVSVK 19 0 O75128-3;O75128;O75128-7;A0A0J9YWK3;A0A3B3IU00;H7C1N2;J3KR05;O75128-5;O75128-4;O75128-2 O75128-3 COBL Protein cordon-bleu 1 SLTLGPS(0.426)LS(0.568)LGS(0.006)ISGVSVK 193.85 1.1295999999999999e-14 954340.0 4032.4 3693.9 3797.4 4418.8 4277.4 2969.6 2823.6 2550.1 2583.2 943.32 True False 4715.005676469653 4060.605979865367 3887.944417719698 4171.228961942893 3439.2741755728202 2813.868948317972 2556.128166906284 2483.1625770542933 2620.974413065731 1114.336448682988 4.231222699429982 3.6439676586586716 3.489022029490987 3.7432401738925303 3.08638758037362 2.5251520325334664 2.293856734137451 2.228377775840585 2.352049433690703 1.0 10.121969172243434 -5.8413444349552615 0.15556212916911188 0.33166612310101806 6.469614071227748 0.9433809125183267 0.21640273238363927 3.552934364062511 0.14779806635335693 1.2951290455686553 4.900318839835913 1.440972076536782e-06 5.8413444349552615 6.13794794812673 SLTNDWEDHLAVK ddPTM_PC-9_AZD4547_30min_R2 3 SLTNDWEDHLAVK 13 0 P07900;P07900-2;P08238 P07900;P08238 HSP90AA1;HSP90AB1 Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta 0 ;; 186.16 3.5035e-05 42036600.0 109249.0 109382.0 146172.0 193573.0 177417.0 163662.0 130390.0 166546.0 130073.0 161313.0 False True 143987.909479634 144737.59241840773 144233.66377291206 148947.73552303723 152785.71199033924 153428.18926782382 141994.45740109993 140810.14254634755 136948.39323070747 155665.48096985585 0.9249829093934886 0.9297988964325091 0.9265616427886313 0.9568449896215624 0.9815002724973158 0.9856275669590147 0.9121769098480911 0.9045688335592847 0.8797608331498177 1.0 17.248089534750655 -10.259807465710292 9.703203819976256 0.9999985559918748 0.9353690497091157 0.28474972380662167 0.03148093966078574 0.0 0.0 0.034132013333861996 0.008278229187676673 5.497845539476942e-11 10.259807465710292 -0.0646295062827591 SLTNDWEDHLAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLTNDWEDHLAVK 13 0 P07900;P07900-2;P08238 P07900;P08238 HSP90AA1;HSP90AB1 Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta 0 ;;; 161.25 6.5532e-05 45407900.0 201627.0 214877.0 240478.0 275576.0 251581.0 224073.0 261385.0 279531.0 237830.0 192235.0 False True 235758.46878522614 236208.56848737903 246211.90753789328 260136.37014944587 202285.5090393195 212322.21742202743 236624.72053647772 272193.6074375763 241307.81381984524 227085.68376857758 1.0381916855026712 1.0401737554186752 1.0842247007909454 1.1455428005516637 0.8907893517649845 0.9349872431342015 1.0420063326300277 1.1986383417942281 1.0626289152853925 1.0 17.792877231088788 -10.905561240630847 5.651829337197678 0.9999842791517933 1.048467997255976 0.028878555600440614 0.08450462129453204 1.8215644582670155e-05 1.989598057876678e-06 0.08903407027180624 0.02158693291326253 1.2429073589280926e-11 10.905561240630847 0.04848371810418273 SLTNDWEDHLAVK ddPTM_PC-9_Lapatinib_30min_R1 4 SLTNDWEDHLAVK 13 0 P07900;P07900-2;P08238 P07900;P08238 HSP90AA1;HSP90AB1 Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta 0 ;;; 138.31 4.1219e-05 58245000.0 279071.0 290777.0 320826.0 337581.0 392455.0 340771.0 360899.0 321565.0 322514.0 346819.0 False True 275091.3963646459 290103.7237217853 294448.9247041731 362407.8328772038 369371.5684962173 326197.01870599936 379584.58432763116 336506.0838307476 286189.07709701854 406766.20204273146 0.6762887255213674 0.7131952513874529 0.7238775572441507 0.890948734327569 0.9080684841593949 0.8019275374106225 0.9331763121454107 0.8272714943888014 0.7035714266814967 1.0 18.633840285955202 -5.69402796177552 5.5483539626546845 0.8609637860229294 0.701608087082522 0.486973917574138 0.07620211384951055 0.17707356373400082 10.090674030237137 0.020619159148626186 0.03587403473572433 2.022888932061009e-06 5.69402796177552 -0.15935569894040746 SLTNPT(ph)PIQQQLR ddPTM_PC-9_AZD4547_30min_R2 2 SLTNPTPIQQQLR 13 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 S(0.018)LT(0.175)NPT(0.807)PIQQQLR;S(0.486)LT(0.001)NPT(0.513)PIQQQLR 115.09 0.0007206000000000001 40758000.0 44671.0 48629.0 83791.0 126353.0 120510.0 102763.0 104504.0 126128.0 110056.0 138429.0 True False 58875.44878547856 64347.37325807495 82679.87659193325 97224.26798439001 103779.26665401699 96337.21336491895 113804.65354892673 106637.8157331051 115873.33547622284 133582.64284450855 0.4407417575501193 0.481704597901809 0.6189417639249241 0.7278211144359524 0.7768918509481583 0.7211806213256042 0.8519419224352105 0.7982909565371642 0.8674280805411261 1.0 17.02737303682253 -4.687817755376806 0.29036958065823787 0.9483628344760335 1.1384457040041744e-13 0.930371702573465 0.04345748409190389 2.2381567697021767 0.1492337775525922 0.054705318594852455 0.7666314687975723 2.0520230963303357e-05 4.687817755376806 -0.9483628344759197 down SLTNPT(ph)PIQQQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLTNPTPIQQQLR 13 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 S(0.002)LT(0.03)NPT(0.969)PIQQQLR;S(0.042)LT(0.02)NPT(0.938)PIQQQLR;SLT(0.003)NPT(0.997)PIQQQLR;S(0.016)LT(0.349)NPT(0.634)PIQQQLR 132.65 0.00013098 40039400.0 90902.0 102355.0 142854.0 165971.0 217253.0 173626.0 170036.0 208540.0 162934.0 136178.0 True False 106289.91320366136 112516.12795937074 146260.18113681203 156672.1829552417 174683.83421370995 164520.7469088958 153928.95912596586 203066.0459663939 165316.6015091558 160865.99341554526 0.6607357524538809 0.6994401089403757 0.9092050969342921 0.9739297885696064 1.0858965932126547 1.0227192423690796 0.9568769374913204 1.2623304755395905 1.0276665564866394 1.0 17.295499851361612 -5.3817096443060155 1.1649181615398332 1.0689249611758616 0.6061588628813165 0.7783881555043549 0.0784343981980512 0.3132087521692692 0.6710447485869755 0.026287922250133846 0.13733432666744083 4.152315606757503e-06 5.3817096443060155 -0.46276609829454507 SLTNPT(ph)PIQQQLR ddPTM_PC-9_Lapatinib_30min_R1 2 SLTNPTPIQQQLR 13 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 S(0.004)LT(0.043)NPT(0.953)PIQQQLR;S(0.053)LT(0.003)NPT(0.944)PIQQQLR 135.61 0.00012646 35421000.0 82078.0 83255.0 107664.0 108097.0 104059.0 101212.0 80559.0 73984.0 109279.0 67761.0 True False 80907.55266873841 83062.22816267186 98812.28151505832 116046.81398102127 97938.45420786536 96883.39869669545 84729.95084178574 77421.56673187081 96970.84826111449 79473.39856414305 1.018045712534086 1.0451576208312303 1.2433378124040693 1.460196947376798 1.232342594847245 1.2190670142098023 1.0661422862569558 0.97418215567293 1.2201673769223451 1.0 16.278184420049577 -7.2646104190443 21.428242879426406 1.0629713886319994 1.210703570091463 0.2153469715525108 0.12842982699170513 65.1796192538326 440431.52442298474 0.05707599566603591 0.04044264783562372 5.4373786920164904e-08 7.2646104190443 0.14773218145946365 SLTQPIT(ph)TEEVVIAATLQASAHQK ddPTM_PC-9_Lapatinib_30min_R1 1 SLTQPITTEEVVIAATLQASAHQK 24 0 O95425-2;O95425-4 O95425-2 SVIL Supervillin 1 S(0.118)LT(0.101)QPIT(0.754)T(0.028)EEVVIAATLQASAHQK 109.41 0.0023807 0.0 1057.9 551.34 2656.7 1158.3 1055.4 1124.7 2058.7 790.13 2410.2 467.42 True False 1042.8141520049003 550.0634061042283 2438.2763811585673 1243.4852459755282 993.3234469962349 1076.599202803753 2165.289412703535 826.8423243113789 2138.7378954688297 548.212924202 1.9022064347039265 1.003375480256913 4.447681317816097 2.2682523360528095 1.8119300059227081 1.9638340419844948 3.9497233959878173 1.5082503308636197 3.901290540681907 1.0 9.098592530091539 SLTQPITTEEVVIAATLQASAHQK ddPTM_PC-9_AZD4547_30min_R2 3 SLTQPITTEEVVIAATLQASAHQK 24 0 O95425-2;O95425-4 O95425-2 SVIL Supervillin 0 ;; 155.31 1.8337e-08 26663400.0 29057.8 22826.49 71573.5 127346.2 85534.6 80032.0 59241.0 102909.8 63029.2 74848.9 False True 38297.57596021306 30204.70649615898 70624.38862470587 97988.50106917719 73659.59722466762 75027.58638830308 64513.334234976246 87007.45504194718 66360.7948353379 72228.4627932321 0.5302283127615114 0.4181828787167432 0.9777916612579973 1.3566466359624483 1.0198139954263241 1.0387537473015869 0.8931843727542438 1.2046145200545495 0.9187623863089607 1.0 16.140279846007985 -5.3145461522868835 5.064781820190133 1.0663895120523144 0.472477254080705 0.7563772738351124 0.13128138142984874 0.0845952942065768 4.8271529728187605 0.03427780342528371 0.07614223297357545 4.846786033017901e-06 5.3145461522868835 -0.5939122579716094 SLTQPITTEEVVIAATLQASAHQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLTQPITTEEVVIAATLQASAHQK 24 0 O95425-2;O95425-4 O95425-2 SVIL Supervillin 0 200.19 2.8415999999999996e-25 4178100.0 7498.7 10341.0 14332.0 18940.0 20248.0 18145.0 13560.0 12907.0 14907.0 11155.0 False True 8768.081803923964 11367.586138711864 14673.729234412673 17878.85320430848 16280.549751484192 17193.444257553077 12275.498634101576 12568.204926096922 15124.986673726715 13177.313197068584 0.6653922292652575 0.8626634252907254 1.1135600266127832 1.3567904880856743 1.2354984288531559 1.3047761710162522 0.9315630926061903 0.9537759889392957 1.1478050530886226 1.0 13.6857686199703 -5.076152628128811 2.6278396944644977 1.14074180490084 0.6741895073499633 0.560408997406884 0.1351212985540054 0.24584565411794995 3.0661256378529242 0.04010231845111129 0.186415145032809 8.391650191624184e-06 5.076152628128811 -0.4665522975508767 SLTQPITTEEVVIAATLQASAHQK ddPTM_PC-9_Lapatinib_30min_R1 3 SLTQPITTEEVVIAATLQASAHQK 24 0 O95425-2;O95425-4 O95425-2 SVIL Supervillin 0 ;; 158.35 1.3873e-07 17401100.0 66785.0 42760.0 99594.0 55175.0 59701.0 80718.0 56040.0 56228.0 97571.0 38390.0 False True 65832.63365313096 42660.99184716658 91405.76576395743 59232.75355840439 56189.50455668205 77265.87930284828 58941.47699417411 58840.55815040588 86581.52651182035 45025.66034854041 1.4621136734814162 0.9474817585556968 2.030081625819409 1.315533255923131 1.2479440417247214 1.7160410020583516 1.3090641322728498 1.306822769392505 1.9229374059502728 1.0 15.458459814472304 SLTS(ph)SLENIFSR ddPTM_PC-9_AZD4547_30min_R2 4 SLTSSLENIFSR 12 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 S(0.001)LT(0.001)S(0.994)S(0.003)LENIFSR;S(0.168)LT(0.042)S(0.573)S(0.216)LENIFSR;SLT(0.002)S(0.948)S(0.05)LENIFSR;SLT(0.001)S(0.5)S(0.5)LENIFSR 248.67 5.5562e-30 118686000.0 108806.8 126605.6 205271.7 334549.0 289812.0 251424.6 221439.3 302825.0 240083.0 264813.5 True False 143405.09907796583 167528.38429255236 202549.66313585412 257423.89678052507 249576.60631925965 235702.9800160506 241146.9687152336 256030.3544762272 252773.29724084103 255542.45996795586 0.561179144538048 0.6555794458328367 0.7926262553833643 1.0073625213313089 0.9766541589626855 0.9223632739764928 0.9436669301276688 1.001909250260534 0.9891635905537496 1.0 17.96320349826439 -5.406104368919482 1.925398559758312 0.9748810568451746 0.5777283372866447 0.9526536345672268 0.03314125210373968 0.07242735001997876 0.5035607015900487 0.010041122625308948 0.031894627922462074 3.92550586966369e-06 5.406104368919482 -0.3971527195585298 SLTS(ph)SLENIFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SLTSSLENIFSR 12 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 S(0.001)LT(0.003)S(0.986)S(0.01)LENIFSR;SLT(0.215)S(0.685)S(0.099)LENIFSR 182.72 0.00058043 70513000.0 13636.4 15368.6 18603.6 22506.0 29920.0 32234.0 29379.0 36138.0 29985.0 28633.0 True False 15944.773188823227 16894.29304046099 19047.18037854589 21245.061785436472 24057.39078251713 30543.592295286082 26596.00843445947 35189.41579137603 30423.473898953198 33823.9362412967 0.47140501552139735 0.49947743869722117 0.5631272552864676 0.6281073153011006 0.7112534333938553 0.9030170846287977 0.7863073133985976 1.0403702141683961 0.8994658008433751 1.0 15.045756941880207 -6.402156260294459 0.6235729531086716 0.9880566325873343 0.43693534795173244 0.9123905838604013 0.058118225346366355 0.2220855753202814 0.18729350637918596 0.03928632536903565 0.0641725195036681 3.9613547802621494e-07 6.402156260294459 -0.551121284635602 down SLTS(ph)SLENIFSR ddPTM_PC-9_Lapatinib_30min_R1 3 SLTSSLENIFSR 12 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 S(0.001)LT(0.001)S(0.959)S(0.04)LENIFSR;SLT(0.006)S(0.924)S(0.07)LENIFSR;S(0.014)LT(0.152)S(0.505)S(0.33)LENIFSR 245.5 1.0027999999999999e-29 56089800.0 81408.0 69062.2 67278.5 63555.3 120682.1 102804.0 103095.0 110279.5 129086.0 103181.9 True False 80247.10699160126 68902.29071906884 61747.121432520325 68229.36877626562 113583.81614813759 98407.31256782882 108432.7546522909 115403.48816510799 114546.97534415788 121016.75393376045 0.6631074159824614 0.5693615840727565 0.5102361402481357 0.5638010156313691 0.9385792665560064 0.8131709814468573 0.8960144040191533 0.9536157962745808 0.9465381579054429 1.0 16.884847266927864 -6.25985368570797 24.999292901140542 0.9153278574789521 0.5713654268244853 0.8973697481297814 0.05759662275214939 44.07147889147165 694809.2503515182 0.018118228670584068 0.022164880785184356 5.497260459773593e-07 6.25985368570797 -0.34396243065446674 SLTSS(ph)LENIFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLTSSLENIFSR 12 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 SLTS(0.272)S(0.728)LENIFSR 185.95 0.00040249 4906500.0 5649.9 4317.3 5450.6 6067.2 10497.0 12262.0 10690.0 12217.0 10494.0 7737.7 True False 6606.316479388425 4745.893011958298 5580.562975515611 5727.274454127796 8440.188203344998 11618.959133982678 9677.365811102207 11896.316694981484 10647.454897302488 9140.483758400498 0.7227534837329519 0.5192168311219434 0.6105325629386774 0.6265832975048158 0.9233852853343897 1.2711536326843045 1.0587367219167465 1.3014974928485876 1.1648677661635818 1.0 13.15805480633236 -6.44709637613081 2.7645544155518134 1.171481015878135 0.6085984828585147 0.8713563084151528 0.09729565344033601 0.08385199755929171 1.2574212531541258 0.031324576671064905 0.03504881825604034 3.5719356301728497e-07 6.44709637613081 -0.5628825330196203 SLTSS(ph)LENIFSR ddPTM_PC-9_Lapatinib_30min_R1 1 SLTSSLENIFSR 12 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 SLT(0.015)S(0.312)S(0.667)LENIFS(0.006)R 103.13 0.0055173 0.0 8045.7 7248.1 9381.9 7810.4 8955.6 8280.4 8585.4 10244.0 12076.0 9666.8 True False 7930.966842599327 7231.317469771932 8610.556397181295 8384.80287073061 8428.84921538704 7926.266594555171 9029.910003315168 10719.973637560606 10715.873714082483 11337.69349979866 0.6995220714636684 0.6378120443898355 0.7594627952620351 0.7395510269244367 0.7434359744807639 0.69910750318801 0.7964503541637923 0.9455162672858441 0.9451546484540954 1.0 13.468839552911204 -7.667076383085372 2.221767040644249 0.9719734739485051 0.7137729110606635 0.9154282870474967 0.03406586319999602 0.08866798294174684 0.8735613910673435 0.023025882079271236 0.010656057868260077 2.152403139880696e-08 7.667076383085372 -0.25820056288784154 SLTTECHLLDS(ph)PGLNCSNPFTQLER ddPTM_PC-9_AZD4547_30min_R2 2 SLTTECHLLDSPGLNCSNPFTQLER 25 0 Q15398-1;Q15398 Q15398-1 DLGAP5 Disks large-associated protein 5 1 SLTTECHLLDS(1)PGLNCSNPFTQLER;SLTTECHLLDS(1)PGLNCSNPFTQLER 162.02 1.381e-08 36244000.0 23516.0 22632.0 39217.0 74895.0 61683.0 53947.0 37490.0 75738.0 51151.0 49771.0 True False 30993.598836813886 29947.351407118214 38696.95695606739 57629.11486621524 53119.38017608283 50573.68556189762 40826.5373722466 64034.43238609935 53854.73743316385 48028.532439113354 0.6453163830501178 0.6235325104943196 0.805707669813235 1.199893312152994 1.105996320904105 1.052992523267514 0.8500475717013246 1.3332581516471895 1.121307162600408 1.0 15.55160410577707 -5.581056682797073 3.983555773391736 1.0963362558188838 0.6462946469048872 0.7161694230156468 0.11920906043726374 0.11344805698648297 3.6701598582073034 0.034048678950117914 0.06392631879306036 2.6238760606988004e-06 5.581056682797073 -0.4500416089139966 SLTTECHLLDS(ph)PGLNCSNPFTQLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SLTTECHLLDSPGLNCSNPFTQLER 25 0 Q15398-1;Q15398 Q15398-1 DLGAP5 Disks large-associated protein 5 1 SLTTECHLLDS(0.992)PGLNCS(0.008)NPFTQLER;SLTTECHLLDS(0.991)PGLNCS(0.008)NPFT(0.001)QLER;SLTTECHLLDS(0.999)PGLNCSNPFTQLER;SLTTECHLLDS(1)PGLNCSNPFTQLER 170.37 6.2357e-11 18089900.0 26757.5 25460.7 34230.4 36546.3 55755.8 57623.7 53182.2 68178.6 57965.1 41232.6 True False 31287.01626528535 27988.27003209565 35046.58255551492 34498.72929570325 44830.85123635922 54601.81173127368 48144.39701021513 66388.98399119776 58812.72992830457 48707.743982918015 0.6423417244752256 0.5746164314633673 0.71952793723737 0.7082801722001758 0.9204050027872687 1.1210088430788898 0.9884341394891857 1.3630067533918349 1.207461588632198 1.0 15.571863542361749 -6.471906791127712 1.084082825643553 1.1846834095040848 0.6142653824320892 0.8242578585659297 0.10367207588460851 0.18741132285824652 0.46731365915132084 0.04837415957630206 0.058647304419361834 3.373597054883933e-07 6.471906791127712 -0.5704180270719956 SLTTECHLLDS(ph)PGLNCSNPFTQLER ddPTM_PC-9_Lapatinib_30min_R1 3 SLTTECHLLDSPGLNCSNPFTQLER 25 0 Q15398-1;Q15398 Q15398-1 DLGAP5 Disks large-associated protein 5 1 SLTTECHLLDS(1)PGLNCSNPFTQLER;SLTTECHLLDS(0.999)PGLNCSNPFTQLER;SLTTECHLLDS(1)PGLNCSNPFTQLER 153.48 1.041e-07 21776500.0 63945.7 56387.2 82752.5 58354.1 100331.2 107896.5 100383.3 93354.6 120330.0 97779.2 True False 63033.82259179483 56256.63890281924 75948.90888388749 62645.655177571054 94429.91607472856 103282.0182140262 105580.65609474077 97692.19552372278 106777.16826892568 114680.20443740566 0.5496486765176611 0.4905523074256904 0.6622669470853765 0.5462638951935604 0.8234194954393368 0.9006089474700861 0.9206528416363997 0.8518662484338767 0.9310863090343235 1.0 16.807256855984953 -6.3724614647758555 2.6742146330287433 0.9114408881310648 0.559453664979123 0.9079411556405883 0.05397098452904304 0.07941329468587831 1.1047421104757533 0.01780218788531025 0.020840571293799556 4.2416861899069316e-07 6.3724614647758555 -0.35198722315194186 SLTVSDDAES(ph)SEPER ddPTM_PC-9_Lapatinib_30min_R1 1 SLTVSDDAESSEPER 15 0 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 SLTVS(0.002)DDAES(0.499)S(0.499)EPER 166.64 3.5673e-05 3711900.0 34253.0 31855.0 43078.0 33700.0 30808.0 29915.0 27229.0 34042.0 37622.0 23938.0 True False 33764.54593876913 31781.24170466535 39536.29312588877 36178.41041990445 28995.934010858426 28635.605185271 28638.78438747976 35623.71559643091 33384.6141827767 28075.651404619988 1.2026273389764701 1.131985906458277 1.4082057280203613 1.2886044885836956 1.032778673341378 1.0199444626441996 1.020057699632469 1.2688473397475242 1.1890949100929176 1.0 14.777031875632584 -6.254158746277674 24.458653437589685 1.0950509369965393 1.2596044386118233 0.3936106612759728 0.10280232443714828 508.5082077291953 1708287.6795285633 0.03336286974625933 0.042142753050053786 5.569821198193475e-07 6.254158746277674 0.16455350161528393 SLTVSDDAESS(ph)EPER ddPTM_PC-9_AZD4547_30min_R2 2 SLTVSDDAESSEPER 15 0 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 SLTVSDDAES(0.022)S(0.978)EPER;SLTVSDDAES(0.226)S(0.774)EPER 249.82 1.5096e-40 19666600.0 42069.0 42829.0 60225.0 69413.0 65120.0 59104.0 51066.0 64360.0 51401.0 56833.0 True False 55446.066910440706 56672.63668325674 59426.37714968405 53410.90527015956 56079.21205302128 55408.21753666373 55610.775072049735 54414.640845669914 54117.9519227787 54843.293968618855 1.0109908230925508 1.0333558140341574 1.0835668839236319 0.9738821541375887 1.0225354459035523 1.0103006863221622 1.0139940738036273 0.9921840376109755 0.9867742800741475 1.0 15.743027603647562 -5.774245626394528 24.99993935015964 1.0015844327706709 1.041709650436531 0.4574940106553874 0.02124151516210119 209.14120298216042 408278.6481475534 0.006055065853520329 0.009044166910186602 1.6817226506261008e-06 5.774245626394528 0.04012521766586019 SLTVSDDAESS(ph)EPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLTVSDDAESSEPER 15 0 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 SLTVSDDAES(0.015)S(0.985)EPER 260.96 1.4090999999999997e-50 15363000.0 22126.0 26464.0 32630.0 30901.0 34522.0 27005.0 29949.0 24359.0 26830.0 24392.0 True False 25871.494791580066 29091.17102551697 33408.02294996411 29169.71715239368 27757.661918250535 25588.81026041448 27112.013908016834 23719.602060493904 27222.337992626803 28814.076513034233 0.8978769380263473 1.0096166369363735 1.159434102802211 1.0123426006451595 0.9633368574451511 0.8880662980414874 0.940929475763436 0.8231949425748276 0.9447583017388256 1.0 14.814486161848546 -6.440275751829307 2.924601899077754 0.9101451513568437 1.0290346844824285 0.287851891254429 0.0729734584693941 0.3118448513744821 5.195669765219815 0.02514303864763861 0.028192152764386802 3.6284759441736787e-07 6.440275751829307 0.11888953312558481 SLTVSDDAESS(ph)EPER ddPTM_PC-9_Lapatinib_30min_R1 3 SLTVSDDAESSEPER 15 0 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 SLTVSDDAES(0.043)S(0.957)EPER;SLTVSDDAES(0.025)S(0.975)EPER;SLTVSDDAES(0.026)S(0.974)EPER 241.41 6.367099999999999e-92 19240200.0 76886.0 71148.0 81121.0 69727.0 67676.0 67111.0 62879.0 65811.0 72346.0 54100.0 True False 75789.59154083449 70983.26117731996 74451.5445161155 74854.95618245327 63695.43073613531 64240.818973382 66134.56695069007 68868.81931486743 64197.631642846194 63451.11291628123 1.1944564572229477 1.1187078983307481 1.173368615525286 1.1797264498925104 1.0038504891187086 1.0124458976494664 1.0422916779718183 1.085383945995312 1.0117652582004344 1.0 15.953357848339532 -6.258716627102315 24.999803495471937 1.0303666645591862 1.1636324891000511 0.8433794821987155 0.029637243632165067 96.73439232341359 888196.5564835484 0.009145083308943345 0.011282587920971344 5.511672103117804e-07 6.258716627102315 0.13326582454086489 SLTWPPS(ph)GSPSHAGTTPPENGLSEHPCETEQINAK ddPTM_PC-9_AZD4547_30min_R2 2 SLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAK 35 0 P23497;P23497-5;P23497-2;P23497-3;P23497-4;E9PHV6;P23497-7;P23497-6 P23497 SP100 Nuclear autoantigen Sp-100 1 S(0.019)LT(0.018)WPPS(0.306)GS(0.306)PS(0.306)HAGT(0.017)T(0.025)PPENGLS(0.001)EHPCETEQINAK;S(0.026)LT(0.023)WPPS(0.401)GS(0.401)PS(0.126)HAGT(0.011)T(0.011)PPENGLSEHPCETEQINAK 63.657 5.0673999999999996e-05 27984000.0 4817.1 5534.2 36361.0 70978.0 52266.0 43628.0 21450.5 49536.0 23743.0 39825.0 True False 6348.837598095606 7323.021922820503 35878.82938214467 54615.118699168466 45009.76807683063 40899.93426315584 23359.55294487533 41881.349424038315 24998.006507704817 38430.738871786576 0.16520206960570624 0.1905511613308222 0.9335971785982143 1.4211311128150972 1.1711918479369638 1.0642505313157533 0.6078351244509753 1.0897877754514098 0.6504690578836821 1.0 15.2299730935618 -5.274112600680785 5.096508669593445 1.0095451534620266 0.16699774528365938 0.6816852948296537 0.22285866923172598 0.09648797863318352 8.009449484072533 0.06185910417297798 0.14716246348229892 5.3197031603206686e-06 5.274112600680785 -0.8425474081783672 SLTWPPSGS(ph)PSHAGTTPPENGLSEHPCETEQINAK ddPTM_PC-9_AZD4547_30min_R2 1 SLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAK 35 0 P23497;P23497-5;P23497-2;P23497-3;P23497-4;E9PHV6;P23497-7;P23497-6 P23497 SP100 Nuclear autoantigen Sp-100 1 S(0.083)LT(0.073)WPPS(0.18)GS(0.551)PS(0.107)HAGT(0.003)T(0.003)PPENGLSEHPCETEQINAK 67.214 1.4154e-05 13041000.0 17483.0 10307.0 78696.0 134400.0 109040.0 97144.0 50144.0 104040.0 69382.0 81264.0 True False 23042.23033100941 13638.536185629539 77652.43962094709 103416.15645930063 93901.6781674052 91069.5703231873 54606.7188582004 87963.00860135937 73049.39087383963 78418.97209483644 0.2938348937186164 0.1739188339415581 0.9902251654999719 1.3187644991601484 1.19743571815561 1.161320633137754 0.6963457617394098 1.1217057078353538 0.9315270134566023 1.0 16.25891511087856 -5.288525927166302 5.998614806740395 1.0650960521338102 0.23077006422512322 0.8026871839035803 0.1623116103949967 0.06804087337189342 8.596011114186664 0.04492870260434781 0.10014954455842684 5.146050844270247e-06 5.288525927166302 -0.834325987908687 down SLTWPPSGS(ph)PSHAGTTPPENGLSEHPCETEQINAK ddPTM_PC-9_Lapatinib_30min_R1 2 SLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAK 35 0 P23497;P23497-5;P23497-2;P23497-3;P23497-4;E9PHV6;P23497-7;P23497-6 P23497 SP100 Nuclear autoantigen Sp-100 1 S(0.004)LT(0.003)WPPS(0.08)GS(0.432)PS(0.393)HAGT(0.073)T(0.014)PPENGLS(0.001)EHPCETEQINAK;S(0.009)LT(0.007)WPPS(0.278)GS(0.421)PS(0.278)HAGT(0.005)T(0.002)PPENGLSEHPCETEQINAK 71.881 4.4621e-06 18760200.0 15638.599999999999 11666.2 39155.0 17625.8 28503.0 35295.0 17189.4 23791.5 31485.0 13213.099999999999 True False 15415.590696232 11639.187630669187 35935.82704267087 18922.06012994515 26826.50957905408 33785.515126663544 18079.383023619852 24896.939945140886 27938.827748251646 15496.966729650934 0.9947489057156434 0.7510623100454548 2.318894250054334 1.221017019655908 1.7310813172055084 2.180137294998539 1.1666401134505815 1.606568587225823 1.8028578260283175 1.0 13.919698239414464 -5.229836751173659 24.99254334539947 1.6423941368103543 0.8729053024460968 0.3589737501220658 0.4034823846605472 672.4541329457677 531799.9295834742 0.09690204612049248 0.25632606360059107 5.890650399434584e-06 5.229836751173659 -0.7694888343642575 SLTWPPSGSPS(ph)HAGTTPPENGLSEHPCETEQINAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAK 35 0 P23497;P23497-5;P23497-2;P23497-3;P23497-4;E9PHV6;P23497-7;P23497-6 P23497 SP100 Nuclear autoantigen Sp-100 1 S(0.008)LT(0.016)WPPS(0.085)GS(0.077)PS(0.507)HAGT(0.204)T(0.085)PPENGLS(0.016)EHPCET(0.001)EQINAK;S(0.002)LT(0.002)WPPS(0.313)GS(0.313)PS(0.344)HAGT(0.021)T(0.006)PPENGLSEHPCETEQINAK;SLT(0.001)WPPS(0.114)GS(0.114)PS(0.424)HAGT(0.179)T(0.163)PPENGLS(0.004)EHPCETEQINAK 75.225 3.4468999999999996e-08 26360700.0 17421.9 30624.7 69428.0 80251.0 94576.0 94939.0 72754.0 58288.9 72603.0 47415.8 True False 20371.083571790146 33664.91782440859 71083.4268271564 75754.79664725231 76044.51171949657 89960.23170944229 65862.21442665394 56758.87813719459 73664.68152361864 56011.90919673373 0.36369200521695594 0.6010314289799592 1.2690770203437656 1.3524766024520705 1.357648985904073 1.6060911509634495 1.1758609083529439 1.013335895011849 1.315161053783796 1.0 15.773445983726827 -5.180309963750742 3.2337513221221847 1.281550729992872 0.402755713768807 0.7765849666378006 0.16879118922417505 0.11529585329389565 2.294306992211189 0.046972113519007146 0.15359858760493225 6.602220674958937e-06 5.180309963750742 -0.878795016224065 down SLTWPPSGSPS(ph)HAGTTPPENGLSEHPCETEQINAK ddPTM_PC-9_Lapatinib_30min_R1 2 SLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAK 35 0 P23497;P23497-5;P23497-2;P23497-3;P23497-4;E9PHV6;P23497-7;P23497-6 P23497 SP100 Nuclear autoantigen Sp-100 1 S(0.001)LT(0.001)WPPS(0.327)GS(0.327)PS(0.343)HAGT(0.001)TPPENGLSEHPCETEQINAK;S(0.011)LT(0.011)WPPS(0.303)GS(0.303)PS(0.368)HAGT(0.002)T(0.002)PPENGLSEHPCETEQINAK 73.548 9.9803e-07 15201200.0 35236.6 23315.6 60930.0 30693.7 49988.0 59516.0 31734.9 40771.2 63236.0 28462.3 True False 34734.119622398954 23261.614160706198 55920.570596601625 32951.01708918163 47047.80412018931 56970.63941857226 33377.97784194176 42665.5787945833 56113.695775399145 33381.97063136916 1.04050536758184 0.696831664540714 1.6751728414754778 0.9870902306233965 1.409377673946496 1.7066290078464315 0.9998803908411674 1.2781024603289988 1.680958155378308 1.0 15.026781503099162 -5.24916558765058 24.991204352711843 1.342596864519661 0.8686685021835925 0.3132174028449193 0.2804464045936817 874.7098212317131 1781027.317485308 0.06849418732820921 0.17839471448539945 5.6342279321851295e-06 5.24916558765058 -0.4739283623360686 SLTWPPSGSPSHAGT(ph)TPPENGLSEHPCETEQINAK ddPTM_PC-9_AZD4547_30min_R2 1 SLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAK 35 0 P23497;P23497-5;P23497-2;P23497-3;P23497-4;E9PHV6;P23497-7;P23497-6 P23497 SP100 Nuclear autoantigen Sp-100 1 S(0.001)LT(0.002)WPPS(0.053)GS(0.091)PS(0.273)HAGT(0.312)T(0.117)PPENGLS(0.151)EHPCETEQINAK 56.247 0.0066443 9727300.0 8078.3 7941.2 40008.0 85794.0 61197.0 57212.0 32840.0 63354.0 33796.0 51907.0 True False 10647.031360921657 10508.037601370059 39477.4677792372 66015.51880408674 52700.85288711216 53634.52459575669 35762.69638049021 53564.095030089724 35582.38756409856 50089.75172926116 0.21255907632502663 0.20978418216498226 0.7881346266720557 1.3179446199075917 1.0521284507849868 1.0707684255584913 0.7139723225978489 1.0693623581847171 0.710372607882427 1.0 15.612227840419543 -5.341519191077839 3.7049631916874652 0.9911909617278953 0.20074711941262255 0.7665735705214141 0.1690735492749829 0.10228095586014044 2.6552126555641746 0.04604843400684228 0.10926254625719019 4.554920579415896e-06 5.341519191077839 -0.7904438423152728 down SLVESVS(ph)SSPNKESNEEEQVWHFLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLVESVSSSPNKESNEEEQVWHFLGK 26 1 Q9H2U2-4;Q9H2U2-6;Q9H2U2-3;Q9H2U2;Q9H2U2-2 Q9H2U2-4 PPA2 Inorganic pyrophosphatase 2, mitochondrial 1 SLVES(0.004)VS(0.28)S(0.236)S(0.199)PNKES(0.28)NEEEQVWHFLGK 72.916 5.9286e-05 48041000.0 24565.0 23443.0 21831.0 27163.0 31839.0 28530.0 28217.0 24587.0 20650.0 19605.0 True False 28723.369319134268 25770.26611061042 22351.53383452854 25641.14517363417 25600.376508173897 27033.836575805406 25544.08148661093 23941.617302079878 20951.96718403814 23159.2313069054 1.2402557294969374 1.1127427231544809 0.9651241674789083 1.107167368115052 1.1054070046159357 1.1673028442763864 1.1029762235240699 1.0337828999938006 0.9046918227286276 1.0 14.49929974824275 -7.96972662900034 3.283004303514942 0.9535072270906637 1.1098638559726095 0.47727245672741025 0.06797193170918434 0.22743554041368863 4.96029173854431 0.049073524834040094 0.01909983151831434 1.0721939960905155e-08 7.96972662900034 0.1563566288819458 SLVESVSSS(ph)PNK ddPTM_PC-9_Lapatinib_30min_R1 1 SLVESVSSSPNK 12 0 Q9H2U2-4;Q9H2U2-6;Q9H2U2-3;Q9H2U2;Q9H2U2-2 Q9H2U2-4 PPA2 Inorganic pyrophosphatase 2, mitochondrial 1 SLVESVS(0.007)S(0.228)S(0.765)PNK 117.2 0.0016351 0.0 23745.0 40741.0 40096.0 39205.0 40350.0 38567.0 37599.0 40003.0 35250.0 35489.0 True False 23406.39194570031 40646.6667176196 36799.46165503589 42088.266484046086 37976.692331152226 36917.5793140681 39545.69224668008 41861.685418131274 31279.77380104402 41623.22636387997 0.5623396836438426 0.9765381078890171 0.884108822639706 1.0111726110825872 0.9123918458206749 0.8869466050355154 0.9500871436770039 1.005728990159644 0.751498058501975 1.0 15.345101177365741 -4.757104960027264 24.99997553392287 0.930807904458364 0.5623391397855043 0.6862036393857637 0.07477831252412094 70.28421135565124 405332.03752115805 0.017351315667324764 0.13259209648483194 1.749423837836335e-05 4.757104960027264 -0.3684687646728597 SLVESVSSS(ph)PNKESNEEEQVWHFLGK ddPTM_PC-9_Lapatinib_30min_R1 1 SLVESVSSSPNKESNEEEQVWHFLGK 26 1 Q9H2U2-4;Q9H2U2-6;Q9H2U2-3;Q9H2U2;Q9H2U2-2 Q9H2U2-4 PPA2 Inorganic pyrophosphatase 2, mitochondrial 1 S(0.062)LVES(0.027)VS(0.09)S(0.09)S(0.379)PNKES(0.353)NEEEQVWHFLGK 49.888000000000005 0.009739200000000002 3663700.0 27826.0 19852.0 20218.0 20403.0 21103.0 25441.0 20653.0 22966.0 22526.0 19235.0 True False 27429.196137336567 19806.033913703242 18555.754083736927 21903.504682412768 19861.76303009431 24352.947735867612 21722.3112840949 24033.08420150496 19988.884670704036 22559.744120973563 1.2158469524410929 0.8779369928797098 0.8225161590589954 0.9709110424727426 0.8804072831495031 1.07948687739002 0.9628793291099383 1.0653083684207947 0.8860421715563952 1.0 14.46146308392197 -6.751323614605353 24.989473570774663 1.000583630147096 0.9430122138683731 0.035659296966816356 0.11083651684441306 678.4729808552736 1676063.1864533394 0.036324488216712136 0.035915597452797036 1.7728679357396242e-07 6.751323614605353 -0.057571416278722976 SLVESVSSSPNKES(ph)NEEEQVWHFLGK ddPTM_PC-9_Lapatinib_30min_R1 1 SLVESVSSSPNKESNEEEQVWHFLGK 26 1 Q9H2U2-4;Q9H2U2-6;Q9H2U2-3;Q9H2U2;Q9H2U2-2 Q9H2U2-4 PPA2 Inorganic pyrophosphatase 2, mitochondrial 1 S(0.01)LVES(0.045)VS(0.226)S(0.226)S(0.226)PNKES(0.268)NEEEQVWHFLGK 44.632 0.018876 15898000.0 28707.0 21725.0 25358.0 21047.0 22327.0 22565.0 18790.0 22081.0 22688.0 18898.0 True False 28297.632915780956 21674.697097280034 23273.163124710707 22594.86659073378 21013.769756570902 21599.947551584144 19762.8542598239 23106.96387065363 20132.638524768416 22164.494119997846 1.2767100734435217 0.9779017278686323 1.0500200455156146 1.019417202504416 0.9480825342912426 0.974529237375901 0.8916447247940086 1.0425215998864348 0.9083283568653077 1.0 14.435962814513754 -2.434698998697164 1.351163349920122 0.9733224744897435 199.99289586217645 0.7417622183755712 0.051932438896886216 453.75164271233075 1.6747241216226085 0.014445429535728197 279004.10436784854 0.0036753694515816436 2.434698998697164 199.0195733876867 SLVGS(ph)WLK ddPTM_PC-9_AZD4547_30min_R2 2 SLVGSWLK 8 0 Q6ICG6-2;B0QY16;Q6ICG6-3;Q6ICG6 Q6ICG6-2 KIAA0930 Uncharacterized protein KIAA0930 1 SLVGS(1)WLK;SLVGS(1)WLK 81.017 0.01848 20086400.0 43608.0 51151.0 59136.0 81837.0 82996.0 78239.0 63970.0 80316.0 66864.0 67918.0 True False 57474.436897252104 67684.56043767705 58351.81800122403 62970.74401904613 71473.43801524189 73346.7029617459 69663.20607368927 67905.0076780736 70398.29453443857 65540.21149263026 0.8769339553277895 1.0327180656914405 0.8903208682472051 0.9607955571844156 1.0905280344308745 1.1191099523686074 1.0629078620157126 1.036081607483205 1.0741237010252032 1.0 16.000092707890552 -6.191401415339442 5.335850467834191 1.0682210431663721 0.941333215708034 0.6037918690133836 0.049104633945675144 0.14887512646987486 8.044166643622956 0.014194177297452676 0.01837817593388951 6.435741394650399e-07 6.191401415339442 -0.12688782745833815 SLVGS(ph)WLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLVGSWLK 8 0 Q6ICG6-2;B0QY16;Q6ICG6-3;Q6ICG6 Q6ICG6-2 KIAA0930 Uncharacterized protein KIAA0930 1 S(0.202)LVGS(0.798)WLK 99.568 0.0051596 9435600.0 23730.0 31285.0 30185.0 34266.0 36167.0 36752.0 38602.0 39842.0 36979.0 26483.0 True False 27747.020311136024 34390.76804463793 30904.72487724999 32346.187111870888 29080.33597698184 34824.66042180166 34945.339105721934 38796.18971608842 37519.74791760516 31284.158260687356 0.8869351727453633 1.0993029685524394 0.9878713890821166 1.0339478160906157 0.9295546881798349 1.1131723644795457 1.117029865867778 1.2401225371897224 1.1993209983454673 1.0 14.933144666598718 -6.921313228717105 5.15171467148789 1.1537190743134877 0.9966878713588819 0.4542796997833528 0.07953687876874813 0.18105304863576616 8.493431217641355 0.02773733352349821 0.02429909252355157 1.1986344932436238e-07 6.921313228717105 -0.15703120295460582 SLVGS(ph)WLK ddPTM_PC-9_Lapatinib_30min_R1 1 SLVGSWLK 8 0 Q6ICG6-2;B0QY16;Q6ICG6-3;Q6ICG6 Q6ICG6-2 KIAA0930 Uncharacterized protein KIAA0930 1 S(0.001)LVGS(0.999)WLK 94.616 0.0066787999999999995 20280000.0 38211.0 32888.0 33583.0 38317.0 44087.0 29186.0 37700.0 31827.0 36336.0 35048.0 True False 37666.10413296079 32811.84985663271 30821.935374128865 41134.96000176494 41493.8893383769 27937.78281588898 39651.92153248328 33305.798610175865 32243.45704495705 41106.00010147554 0.9163164511257987 0.7982253144463671 0.7498159708568307 1.0007045175939744 1.0094363167407145 0.679652185737384 0.9646261235488085 0.8102417780362026 0.784397824292314 1.0 15.327061374060944 -12.071610978574931 2.0954283215807328 3.0129996385416247 0.8574397587735936 0.14013697821681304 0.10622785102598717 9791846.681287043 427202.04294717684 94128524.92967086 0.029620431575147804 8.479866622765837e-13 12.071610978574931 -2.155559879768031 SLVGT(ph)PYWMAPELISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SLVGTPYWMAPELISR 16 0 O96013;O96013-2;O96013-4;O96013-3;M0R1R1 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 SLVGT(0.842)PY(0.157)WMAPELISR;S(0.199)LVGT(0.696)PY(0.105)WMAPELISR;S(0.043)LVGT(0.68)PY(0.277)WMAPELISR 109.16 0.0027289000000000002 18897400.0 33812.0 31656.4 32666.6 31586.7 39112.7 32504.2 34434.3 32397.8 24933.1 25564.5 True False 39535.703782559256 34799.03818214083 33445.49563277039 29816.999604463104 31448.847207866245 30799.622531626155 31172.433821256935 31547.392078306562 25297.699418709042 30199.141481529332 1.3091664809988204 1.1523187903677636 1.1074982265051019 0.9873459357346315 1.0413821607180875 1.0198840437389287 1.0322291393721539 1.0446453286627986 0.8376959800059829 1.0 14.8822199159228 -1.5228787571567897 0.49667571961914136 0.9821971104960335 11.213783952256223 0.762135030415882 0.0563859896876657 50.68039832782881 0.5434462896398787 0.03091356885535804 540.1182054149333 0.029999999179603765 1.5228787571567897 10.23158684176019 SLVGT(ph)PYWMAPELISR ddPTM_PC-9_Lapatinib_30min_R1 1 SLVGTPYWMAPELISR 16 0 O96013;O96013-2;O96013-4;O96013-3;M0R1R1 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 S(0.358)LVGT(0.638)PY(0.004)WMAPELISR 152.11 0.00011954 70215000.0 27862.0 26223.0 26240.0 22412.0 24188.0 25872.0 23140.0 17191.0 21861.0 19367.0 True False 27464.682770734955 26162.28225463631 24082.648489329153 24060.253244240295 22765.30939543769 24765.514870577677 24338.075975110438 17989.75661883097 19398.783973464502 22714.560145094623 1.2091223688813606 1.1517846741261353 1.0602295767778702 1.0592436345035845 1.0022342167323026 1.090292513365088 1.071474676139235 0.7919922949824758 0.854024196354681 1.0 14.471329748222345 -7.711486118882916 8.355925359700626 0.8675716849841741 1.0888497016207945 0.6418776161974487 0.0716416246761169 0.15658265965766838 23.63866306536577 0.03523024346796454 0.02014526533969836 1.943183799757258e-08 7.711486118882916 0.2212780166366204 SLVGT(ph)PYWMAPEVISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SLVGTPYWMAPEVISR 16 0 Q9NQU5-2;Q9NQU5 Q9NQU5-2 PAK6 Serine/threonine-protein kinase PAK 6 1 S(0.003)LVGT(0.986)PY(0.01)WMAPEVISR 94.45 0.0099255 4270300.0 9476.9 9795.0 12094.0 9816.2 13974.0 11061.0 10266.0 10883.0 10526.0 10058.0 True False 11081.15199269299 10767.382867100157 12382.366826750418 9266.230138549792 11235.895013198342 10480.941688222352 9293.530160596374 10597.332781491656 10679.922836764435 11881.435780915806 0.9326441851827161 0.9062358342579218 1.042160817519985 0.7798914465736028 0.945668117926089 0.8821275375705894 0.7821891505337952 0.8919235837232145 0.8988747684786325 1.0 13.536421564917582 -5.757095908247774 24.99986047379297 0.8768305125573848 0.9549358011979633 0.1981540889316099 0.07034355349142012 173.20762304590713 996920.6490653136 0.018602085827090307 0.030835623270422538 1.749460300569571e-06 5.757095908247774 0.07810528864057853 SLVHEVGKPPQDVTDDS(ph)PPSK ddPTM_PC-9_AZD4547_30min_R2 1 SLVHEVGKPPQDVTDDSPPSK 21 1 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 SLVHEVGKPPQDVT(0.015)DDS(0.919)PPS(0.066)K 47.208 0.026369 6911500.0 20507.0 14660.0 64617.0 99216.0 82903.0 68935.0 41165.0 82511.0 54149.0 55292.0 True False 27027.799427901944 19398.558308074997 63760.13636000221 76343.28407191951 71393.34945994498 64624.483552549915 44828.605252828274 69760.82086415593 57011.20559262555 53356.24390957499 0.5065536373532414 0.3635667896891417 1.1949892212813766 1.4308219334423464 1.3380505115940735 1.2111887722470058 0.8401754315540118 1.307453743977602 1.0685011053110256 1.0 15.703369489029964 -5.264517499334553 24.691981007499088 1.1893297572518382 0.43506016210942716 0.7585021710645756 0.16657616098817019 96.19871104438806 771692.9705565461 0.045158040572472594 0.10091382149049326 5.438542173764861e-06 5.264517499334553 -0.754269595142411 SLVHEVGKPPQDVTDDS(ph)PPSK ddPTM_PC-9_Lapatinib_30min_R1 1 SLVHEVGKPPQDVTDDSPPSK 21 1 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 SLVHEVGKPPQDVT(0.036)DDS(0.952)PPS(0.012)K 91.889 0.00019365 5225000.0 9032.9 5456.0 16655.0 7525.4 12444.0 15150.0 11385.0 11744.0 19384.0 9332.8 True False 8904.089189569018 5443.366967215643 15285.6901901592 8078.843019998486 11712.068385845314 14502.06981637491 11974.459592767162 12289.669113579836 17200.769797430836 10945.962044825685 0.8134588036305234 0.49729452239319627 1.3964684079445504 0.7380660545792292 1.0699898590806625 1.3248785037794142 1.0939613661850456 1.122758243017053 1.5714260406705767 1.0 13.418111138664395 -5.08626907329531 0.5419108011226005 1.2353260418178924 0.41710407005513706 0.32092640984515775 0.25193868426929045 3.558918209377181 1.008915174535713 0.14851692653175536 1.7656821738464843 8.198434413328708e-06 5.08626907329531 -0.8182219717627554 SLVPAAELLESR ddPTM_PC-9_Lapatinib_30min_R1 2 SLVPAAELLESR 12 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 119.22 0.0025278 5801300.0 36621.0 30965.0 32978.0 33864.0 38546.0 33758.0 31202.0 31575.0 33143.0 32384.0 False True 36098.7778245311 30893.302444983936 30266.67613876134 36354.471526992405 36278.800064351766 32314.24903374156 32817.486887441475 33042.08977020462 29410.08632873764 37981.5312510324 0.9504297650861528 0.8133769605232597 0.7968787761272432 0.9571618186405855 0.9551694960525229 0.8507884745395357 0.8640380154907378 0.8699514917347225 0.7743259779169179 1.0 15.213010449432304 -4.20690824676436 5.800707136824584 0.8734088125280343 6.199879843584714 0.090776851095272 0.07044879110289189 2995.720621295858 992.9831265755153 0.01763865876432688 206251.19128768783 6.210002188600054e-05 4.20690824676436 5.32647103105668 SLYASS(ph)PGGVYATR ddPTM_PC-9_AZD4547_30min_R2 1 SLYASSPGGVYATR 14 0 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 1 SLYAS(0.205)S(0.795)PGGVYATR 199.38 6.1999e-08 8051100.0 19430.0 22994.0 34724.0 49547.0 32247.0 39272.0 21580.0 36174.0 27714.0 31495.0 True False 25608.335830893593 30426.360827822413 34263.53707174144 38124.70464351914 27770.060673737356 36816.315631765305 23500.578194000584 30584.139495824482 29178.90546074764 30392.369636331907 0.8425909574448139 1.00111841201911 1.1273730045314345 1.2544169835952435 0.9137181801230869 1.2113670658886049 0.7732394174986382 1.0063098028152213 0.9600733937463811 1.0 14.891421543034465 -7.258084355261305 24.997735139952276 0.9354314757830271 1.0612900107915526 0.17406719261801595 0.1317276725726072 548.1161982153297 4083941.520329123 0.05205439518955098 0.03861600634211746 5.519702168405546e-08 7.258084355261305 0.1258585350085255 SLYASS(ph)PGGVYATR ddPTM_PC-9_Lapatinib_30min_R1 1 SLYASSPGGVYATR 14 0 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 1 SLYAS(0.306)S(0.684)PGGVYAT(0.01)R 85.287 0.0069535 5630000.0 31069.0 25367.0 29848.0 32705.0 30555.0 27272.0 22824.0 18686.0 22704.0 29314.0 True False 30625.9503626432 25308.264270043834 27394.012656611925 35110.23480068173 28757.8149734413 26105.64013413709 24005.715041310305 19554.219776596783 20146.83643628096 34380.88584155026 0.8907842137572524 0.736114374326507 0.7967803035343987 1.021213791945117 0.836447760711467 0.7593067919904407 0.6982285201127286 0.5687526454878298 0.5859894514972893 1.0 15.069319096638468 -6.979849847385226 2.5564870113244313 0.6782031903317248 0.8555106425890865 0.19645837485418094 0.13075071737418817 0.3901850181220159 5.150309507696743 0.053117034055174456 0.04297943385719207 1.0474906440003249e-07 6.979849847385226 0.17730745225736166 SLYGDVDS(ph)PLPTGEAGGPPSTR ddPTM_PC-9_Lapatinib_30min_R1 1 SLYGDVDSPLPTGEAGGPPSTR 22 0 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;J3QL92 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 SLY(0.001)GDVDS(0.995)PLPT(0.003)GEAGGPPS(0.001)TR 94.911 0.0017437999999999998 0.0 5691.6 5829.3 4216.1 3786.4 7820.4 14507.0 10753.0 13749.0 16827.0 10236.0 True False 5610.43674028839 5815.8026140011225 3869.4685326166427 4064.8644870601242 7360.419447497962 13886.56942746871 11309.737725166915 14387.828733192186 14931.766063834546 12005.278961387343 0.46733080991564413 0.4844371074346982 0.32231392082283467 0.3385897570672014 0.6130985769819532 1.1567052687515362 0.9420637172649214 1.1984585097495737 1.2437666889590557 1.0 13.55138130677744 -6.6414739162436955 3.431728769774225 1.1129665326712026 0.40737589864673457 0.9221889985797085 0.09758905958354207 0.06342458208559457 1.4602635498463128 0.0354795392296405 0.03524722863864181 2.2831060440666905e-07 6.6414739162436955 -0.705590634024468 down SLYSTS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 SLYSTSPR 8 0 F5H4N6;Q9Y3R0-3;Q9Y3R0-2;Q9Y3R0;F5H4P8;H0YFK8;H0YGM4 F5H4N6 GRIP1 Glutamate receptor-interacting protein 1 1 SLYS(0.018)T(0.104)S(0.878)PR 81.525 0.017759999999999998 9191300.0 36395.0 39974.0 52791.0 82407.0 73083.0 48464.0 54406.0 78493.0 62277.0 56347.0 True False 47967.85293697234 52894.81376582466 52090.95684697334 63409.33932545826 62936.68695440657 45433.538418666576 59248.0286016124 66363.71043970119 65568.83507898469 54374.30868069196 0.8821786262821117 0.9727905521786863 0.9580067887000203 1.1661635957125207 1.1574710277972704 0.8355699506079384 1.0896327703132909 1.2204975483810905 1.2058789650831523 1.0 15.730637532974681 -3.282352787105063 0.47197245077443295 1.1107434847171938 1.807940064599437e-13 0.2769892944907454 0.11120315981028725 25.611989071685723 1.443980040812812 0.07286015402969533 21.494730521632263 0.0005219720072196404 3.282352787105063 -1.110743484717013 SLYSTS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 SLYSTSPR 8 0 F5H4N6;Q9Y3R0-3;Q9Y3R0-2;Q9Y3R0;F5H4P8;H0YFK8;H0YGM4 F5H4N6 GRIP1 Glutamate receptor-interacting protein 1 1 SLYS(0.007)T(0.222)S(0.772)PR 93.598 0.007104899999999999 8747300.0 96387.0 75055.0 101130.0 93832.0 78083.0 76099.0 78782.0 70971.0 92470.0 62869.0 True False 95012.5037047889 74881.21475886548 92815.48177308917 100732.71829437591 73490.31145708452 72844.4231654334 82860.94647671355 74268.57175237364 82055.05484773162 73735.82288232331 1.288552836203124 1.015533723389378 1.2587569805956533 1.3661299807440621 0.9966703914645314 0.9879109002646853 1.1237542789608959 1.0072251023888423 1.1128248338488764 1.0 16.170078069948516 -6.284593128249601 24.98954499925313 1.0402023316107223 1.2186579670637965 0.5017861223828126 0.094386864858181 733.6477689966804 791814.3093338405 0.02987910519074632 0.033900075773164895 5.192863080340971e-07 6.284593128249601 0.1784556354530742 SLYYYIQQDTK ddPTM_PC-9_Lapatinib_30min_R1 2 SLYYYIQQDTK 11 0 P07355;P07355-2;A6NMY6 P07355 ANXA2;ANXA2P2 Annexin A2;Putative annexin A2-like protein 0 ; 172.34 0.0059262 46401000.0 196880.0 179867.0 231222.0 206395.0 192629.0 156408.0 222710.0 208589.0 202765.0 227571.0 False True 194072.45509662936 179450.52901249527 212211.81970273075 221573.9768135359 181298.94094318541 149718.7944448558 234240.83407160084 218280.80643158243 179927.47048989186 266906.3441307026 0.7271181797072351 0.6723351953171234 0.7950797137995782 0.83015627648413 0.6792605156451594 0.5609413104528505 0.8776143363489868 0.8178179770979572 0.6741221197866407 1.0 18.02597407192541 -14.52287871394159 0.3302890670759611 3.639673853228496 0.7295843828484144 0.43036879276939866 0.09028348084135052 366.13601267147254 3.1646258152987237 678.5810124669152 0.07971108972665142 3.000000216480402e-15 14.52287871394159 -2.9100894703800817 SMAHS(ph)PGPVSQASPGTSSAVLFLSK ddPTM_PC-9_AZD4547_30min_R2 1 SMAHSPGPVSQASPGTSSAVLFLSK 25 0 Q8TDZ2-2;Q8TDZ2;Q8TDZ2-4;H0Y6Z4 Q8TDZ2-2 MICAL1 Protein-methionine sulfoxide oxidase MICAL1 1 S(0.01)MAHS(0.989)PGPVSQASPGTSSAVLFLSK 95.141 0.00066267 0.0 2274.1 901.8 9804.9 18781.0 17876.0 15091.0 8662.4 15995.0 11193.0 12289.0 True False 2997.216495781531 1193.2892143398383 9674.880619592146 14451.330613557497 15394.225962220653 14147.357384369794 9433.33681870763 13523.340278534657 11784.63912903761 11858.765850480493 0.2527426996680342 0.10062507594679329 0.8158421155773254 1.2186201157662588 1.2981305269297403 1.1929873279179866 0.7954737396493422 1.1403665819058835 0.9937492043963513 1.0 13.533666255028875 -5.3991752376478015 3.4307949889468214 1.095198232745026 0.1737914526980164 0.8672509213210292 0.14086250189228613 0.08139353111415218 1.7418983077836003 0.040645747255244696 0.09445816307680338 3.988639284540584e-06 5.3991752376478015 -0.9214067800470096 down SMDAMS(ph)SPTK ddPTM_PC-9_AZD4547_30min_R2 1 SMDAMSSPTK 10 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 SMDAMS(0.833)S(0.165)PT(0.002)K 69.672 0.022578 11918000.0 22527.0 23571.0 24123.0 24377.0 24225.0 27532.0 25265.0 27900.0 27971.0 22976.0 True False 29690.11740929182 31189.86479397243 23803.113258311812 18757.25927089565 20861.77690393797 25810.41968765947 27513.53605520967 23588.69607821926 29449.489956071757 22171.61723335012 1.3391047255061086 1.4067473953617255 1.073584890438557 0.8460032064183998 0.9409226527940455 1.1641198481830153 1.2409350100913856 1.0639140947615493 1.32825177550758 1.0 14.436426386084817 -5.264848156309218 24.217175097282382 1.0796103184634216 1.3729260829222005 0.4320166230422917 0.13330600038022433 173.25903774933602 1230911.6040599202 0.037559290412740816 0.08368640436505155 5.434403029540424e-06 5.264848156309218 0.29331576445877894 SMDAMS(ph)SPTK ddPTM_PC-9_Lapatinib_30min_R1 1 SMDAMSSPTK 10 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 SMDAMS(0.649)S(0.349)PT(0.002)K 80.438 0.015547 5119100.0 46643.0 65062.0 57253.0 56166.0 68263.0 64352.0 63779.0 67504.0 62431.0 54607.0 True False 45977.86226672136 64911.35293639739 52545.87934297116 60296.63500428344 64247.90455022164 61599.814971838845 67081.16454695638 70640.48227546789 55399.36335242496 64045.7471907462 0.7178909495705684 1.013515428949141 0.82044291225887 0.9414619650654265 1.0031564525100058 0.961809607566562 1.0473945185957445 1.1029691333771268 0.8649967528277891 1.0 15.966815154479793 -3.407858882841631 0.5041163226350879 1.006131297863662 2.2281109023208038e-14 0.4100428382233371 0.08423538338104436 16.636885836558193 1.0993190617236195 0.04646010415133826 13.39093989598721 0.00039096791402686747 3.407858882841631 -1.0061312978636399 SMDAMS(ph)SPTKTETVK ddPTM_PC-9_AZD4547_30min_R2 3 SMDAMSSPTKTETVK 15 1 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 SMDAMS(0.971)S(0.029)PTKTETVK;S(0.001)MDAMS(0.497)S(0.497)PT(0.003)KT(0.001)ET(0.001)VK;SMDAMS(0.499)S(0.499)PT(0.001)KTETVK 132.08 1.3325999999999999e-05 74026700.0 115752.0 103342.0 121180.0 161541.0 154065.0 129825.0 125597.0 130348.0 105674.0 141080.0 True False 152558.72820883163 136745.2805370456 119573.0740223946 124300.2182335706 132675.73410547775 121707.02222687729 136774.8896863711 110205.7116990582 111259.71190225333 136140.83214140992 1.1205949442880472 1.0044398758706559 0.8783042687604089 0.9130267259161422 0.974547694608382 0.893978832893131 1.0046573649873287 0.8094978557541589 0.8172398401876044 1.0 17.05474030757538 -4.926240910758302 2.692180893473444 0.9098194943832825 1.1321776197472293 0.5066795093725893 0.06455189988727633 0.28365388752163717 3.444248259266311 0.017204738607324414 0.12353414294813443 1.1851111638705537e-05 4.926240910758302 0.22235812536394683 SMDAMS(ph)SPTKTETVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SMDAMSSPTKTETVK 15 1 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 S(0.013)MDAMS(0.968)S(0.018)PT(0.001)KTETVK;SMDAMS(0.587)S(0.41)PT(0.002)KTETVK 93.823 0.005465 39896000.0 69184.0 64259.0 63023.0 83727.0 84514.0 74567.0 79850.0 91812.0 80593.0 63164.0 True False 80895.48475371419 70638.20884706383 64525.70733605851 79036.0476365963 67954.08838882536 70656.57525229873 72286.02993606273 89402.03228285497 81771.52015802346 74615.1331940512 1.0841699436939918 0.9467008343113908 0.8647804349319705 1.0592495684628431 0.9107279646891134 0.9469469828398286 0.9687851088876142 1.198175604007133 1.095910663931413 1.0 16.187180642333644 -7.724284527851713 17.448933111549465 1.1102787326336956 0.9643227778924274 0.3775399881447332 0.07541988110910634 6.201580167031566 2912.1017091486706 0.03434643346829142 0.019820775715420524 1.8867548374324872e-08 7.724284527851713 -0.1459559547412682 SMDAMSS(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 3 SMDAMSSPTK 10 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 SMDAMS(0.008)S(0.986)PT(0.006)K;SMDAMS(0.028)S(0.97)PT(0.002)K;SMDAMS(0.14)S(0.86)PTK 115.0 0.00069358 25516000.0 115909.0 132321.0 122668.0 104610.0 112039.0 133041.0 139579.0 149088.0 130116.0 122540.0 True False 152765.6509430287 175091.17557181395 121041.34217015252 80493.7807083888 96484.31878391377 124721.92523848261 152001.26059964823 126049.87530141737 136993.6661229214 118249.91189827301 1.2918880740854048 1.480687577361071 1.023606193248422 0.680709012093263 0.8159356504799465 1.054731654648312 1.2854238803189175 1.0659616846890714 1.1585096675655293 1.0 16.851479583126455 -5.273699213267882 21.556670200707998 1.0056211184790669 1.3862877590644378 0.45758300266119956 0.16353699724582638 102.86313323795821 180868.49519807546 0.04847446102885523 0.10260737386969064 5.3247691820345535e-06 5.273699213267882 0.3806666405853709 SMDAMSS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SMDAMSSPTK 10 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 SMDAMS(0.003)S(0.985)PT(0.012)K;SMDAMS(0.004)S(0.995)PT(0.001)K;SMDAMS(0.002)S(0.987)PT(0.01)K;SMDAMS(0.032)S(0.936)PT(0.032)K 107.11 0.0054027 29462200.0 172582.0 288786.0 198856.0 173338.0 211844.0 146615.0 198238.0 144990.0 138501.0 125181.0 True False 201796.7239501253 317454.76555981504 203597.48120557945 163626.4338293786 170334.68893487836 138926.25129904362 179459.461521167 141184.16612960375 140526.31510685105 147875.32436774895 1.3646409555679488 2.1467730800734643 1.376818492713875 1.1065161447927474 1.1518804077905218 0.9394823097973397 1.2135862578050678 0.9547513537721476 0.9503026668423613 1.0 17.17402180758838 -5.556713271458541 3.55747161436695 1.0518382598089178 1.7637714550419306 0.6724773821537784 0.19760067845120105 0.11594330667627833 3.079376225383427 0.051082630771042574 0.10083266244058499 2.775151701916976e-06 5.556713271458541 0.7119331952330128 SMDAMSS(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 6 SMDAMSSPTK 10 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 SMDAMS(0.01)S(0.974)PT(0.016)K;SMDAMS(0.005)S(0.984)PT(0.011)K;S(0.001)MDAMS(0.011)S(0.894)PT(0.094)K;SMDAMS(0.01)S(0.871)PT(0.119)K;SMDAMS(0.127)S(0.87)PT(0.003)K;S(0.003)MDAMS(0.202)S(0.766)PT(0.028)K 92.866 0.0042791 27394300.0 162261.0 225432.0 196131.0 190461.0 248005.0 212019.0 226250.0 235097.0 217603.0 185521.0 True False 159947.12838497697 224910.02605450028 180005.86626755405 204468.13729927057 233417.83349659003 202951.44161042877 237964.11795024775 246020.46488379408 193094.2586788252 217588.05765880592 0.7350914848267355 1.0336505986333853 0.8272782440560984 0.9397029391194421 1.0727511243406858 0.9327324477001929 1.0936451223963448 1.1306708076303171 0.887430407516258 1.0 17.73123985074372 -6.038334830386056 5.218179590004305 1.0246798439770943 0.881747060713383 0.33485110893077963 0.0968662116259335 0.23088010098023998 15.99459204728872 0.02744107045096128 0.03713000466580894 9.155143788443937e-07 6.038334830386056 -0.14293278326371128 SMDAMSS(ph)PTKTETVK ddPTM_PC-9_Lapatinib_30min_R1 3 SMDAMSSPTKTETVK 15 1 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 S(0.001)MDAMS(0.221)S(0.743)PT(0.031)KT(0.002)ET(0.002)VK;SMDAMS(0.038)S(0.917)PT(0.038)KT(0.008)ETVK;SMDAMS(0.27)S(0.717)PT(0.009)KT(0.003)ET(0.001)VK 94.48700000000001 0.006562100000000001 63034400.0 327378.0 236588.0 230408.0 234084.0 239491.0 224186.0 215350.0 206472.0 224521.0 183167.0 True False 322709.52968622727 236040.1950219238 211464.74364060015 251299.31824133213 225404.61023742217 214598.08738309098 226499.7692843572 216065.4428830941 199233.0806690555 214827.17189531375 1.5021820882299055 1.09874459985419 0.9843482171037837 1.1697743633835642 1.049236966854746 0.9989336334403062 1.0543348277876672 1.0057640333708986 0.9274109923401248 1.0 17.712816955094446 -4.763346833262472 3.5732369500850787 1.0304161350063634 1.5672657395379235 0.8507453600348778 0.059745959980317495 0.11077476643323551 2.3234842494799834 0.015505502389929392 0.1652151954242183 1.7244601654497744e-05 4.763346833262472 0.53684960453156 SMDFEEAER ddPTM_PC-9_Lapatinib_30min_R1 2 SMDFEEAER 9 0 K7ER96;O43396 K7ER96 TXNL1 Thioredoxin-like protein 1 0 ; 126.24 0.006453699999999999 3613500.0 24575.8 24183.0 22183.9 20649.9 21132.2 19364.4 17888.9 21315.6 25126.0 21864.0 False True 24225.34458535025 24127.00574929908 20360.02537433039 22168.562532047014 19889.245543503715 18536.22975262116 18815.099710940052 22306.000592423545 22296.04529149026 25643.163268051274 0.9447096807878036 0.9408747858872323 0.793974797941441 0.8645018674301679 0.7756159150725237 0.7228526979631792 0.7337277197147404 0.869861504965517 0.8694732805943962 1.0 14.6462866192612 -5.254306798180588 23.62965838107544 0.8163065374379469 0.9427922778619946 0.24757619062619973 0.0771204155928913 318.70653143846283 1055831.7609350204 0.019727475855712575 0.0497318576674633 5.5679227580340535e-06 5.254306798180588 0.1264857404240477 SMEAEMIQLQEELAAAER ddPTM_PC-9_Lapatinib_30min_R1 1 SMEAEMIQLQEELAAAER 18 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 195.2 1.0992999999999998e-53 0.0 868.46 2125.8 2262.1 2297.6 1126.1 1180.5 900.24 885.22 2504.0 850.89 False True 856.0756011439414 2120.877840708763 2076.1188699585177 2466.5731685689157 1059.8650119977833 1130.012766879907 946.8500222918495 926.3505528544908 2221.9731517110413 997.9652027603428 0.857821093136375 2.1252021962714496 2.0803519643931803 2.471602378265741 1.0620260196109317 1.1323168019829997 0.9487805984345845 0.9282393316843434 2.2265036351619556 1.0 9.962845702050384 -6.284991632737506 24.890682837998014 1.1951467440858137 1.9150348487606241 0.27837397536447306 0.5248192602208689 934.9366198011097 988064.3984096219 0.16289320658010026 0.18480666000429347 5.188100344000202e-07 6.284991632737506 0.7198881046748105 SMES(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SMESSPR 7 0 Q1ED39;H3BPL4 Q1ED39 KNOP1 Lysine-rich nucleolar protein 1 1 SMES(0.591)S(0.409)PR 69.825 0.040119999999999996 135020000.0 245020.0 256850.0 330130.0 304280.0 382250.0 356960.0 314110.0 353310.0 320830.0 275030.0 True False 286497.0466344095 282348.3705374865 338001.5512249978 287232.1780890695 307350.85650458396 338240.38920783426 284355.22684053465 344035.98686288804 325521.53179927135 324890.7618637172 0.8818257711944029 0.8690563219397538 1.040354454174293 0.8840884746656955 0.9460129144377125 1.0410895873663433 0.8752333406137719 1.0589281913999196 1.001941483137088 1.0 18.309595196242448 -1.5228787452898667 0.2719419579661334 1.0076061895763901 0.03904990833691466 0.27713436821417436 0.0623060688521727 68.71018830904245 0.9614556726685003 0.07055207261123506 31.309426885187605 0.029999999999341755 1.5228787452898667 -0.9685562812394755 SMESS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 SMESSPR 7 0 Q1ED39;H3BPL4 Q1ED39 KNOP1 Lysine-rich nucleolar protein 1 1 SMES(0.084)S(0.916)PR 82.241 0.022769 74932000.0 519730.0 501650.0 551290.0 485650.0 512490.0 506720.0 477790.0 463750.0 565950.0 483340.0 True False 512318.554893191 500488.46024628397 505965.0642409391 521366.3210809074 482346.345794107 485048.7668220134 502527.62835557497 485297.5180026091 502206.75128229405 566884.6749899331 0.9037438785980391 0.8828752695690208 0.8925361481150008 0.9197043844767296 0.8508720857600757 0.8556392300261548 0.8864724176297392 0.8560780338809248 0.8859063817366598 1.0 19.11269574268593 -8.58693490820892 20.590165461615435 1.0000000001013816 0.8804327606710712 0.7438303454564854 0.020871773593604342 4773.887762854901 1534512.2790952702 0.021142286330487123 0.005458914863382316 2.5886008639923914e-09 8.58693490820892 -0.11956723943031033 SMGS(ph)QEDDSGNKPSSYS ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SMGSQEDDSGNKPSSYS 17 1 H7C3P9;Q9UNS2-2;Q9UNS2 H7C3P9 COPS3 COP9 signalosome complex subunit 3 1 S(0.008)MGS(0.992)QEDDSGNKPSSYS 100.04 0.0026015 3941200.0 20961.0 23490.0 22534.0 23748.0 28779.0 25355.0 26246.0 25053.0 22777.0 21287.0 True False 24509.283301378924 25821.931959998226 23071.29602067089 22417.476552054795 23139.961541780092 24025.339165073467 23759.788875415208 24395.385295847704 23110.070535149494 25146.16459220072 0.9746728258106078 1.0268735761002337 0.9174876723676036 0.8914869092604186 0.9202183282041005 0.9554275793026947 0.9448673092191758 0.9701433873304928 0.9190296377172869 1.0 14.6180507499272 -10.369145045657882 15.051365918285894 0.9999995401302574 0.9466801893447813 0.16223486169343682 0.03634305479075526 0.0 0.0 0.03821337988930123 0.009268105976202512 4.2742011255493644e-11 10.369145045657882 -0.053319350785476116 SMGS(ph)QEDDSGNKPSSYS ddPTM_PC-9_Lapatinib_30min_R1 1 SMGSQEDDSGNKPSSYS 17 1 H7C3P9;Q9UNS2-2;Q9UNS2 H7C3P9 COPS3 COP9 signalosome complex subunit 3 1 SMGS(1)QEDDSGNKPSSYS 116.06 0.00069913 2938400.0 11095.0 10361.0 12200.0 7521.3 10433.0 9797.7 8653.4 8720.4 10734.0 9072.4 True False 10936.783265426184 10337.009741077947 11196.963093361876 8074.441492321281 9819.351452067198 9378.675210554227 9101.430710588613 9125.581619385348 9525.023885968976 10640.55225178688 1.0278398157003137 0.9714730491870891 1.0522915379210283 0.7588366939286757 0.9228234794315514 0.8814086890066497 0.8553532274661966 0.8576229319162338 0.8951625498920348 1.0 13.377285409170362 -5.738916600156763 24.999938727421096 0.8762845918575127 1.0126286644019806 0.5162903578035045 0.05994393383739289 176.93319778312136 196391.62946882864 0.015138787802574397 0.026196667996723585 1.8242459881934378e-06 5.738916600156763 0.1363440725444679 SMGSQEDDSGNKPS(ph)SYS ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SMGSQEDDSGNKPSSYS 17 1 H7C3P9;Q9UNS2-2;Q9UNS2 H7C3P9 COPS3 COP9 signalosome complex subunit 3 1 SMGSQEDDSGNKPS(0.36)S(0.36)YS(0.28) 94.845 0.0037084 12356000.0 24034.0 25513.0 24972.0 28535.0 28972.0 26016.0 32047.0 24100.0 25320.0 20193.0 True False 28102.481506862314 28045.762030457 25567.427186837383 26936.2764617182 23295.144577242187 24651.675161449468 29011.2761598122 23467.400536060723 25690.257099266142 23853.831052299967 1.1781118699653361 1.17573407680159 1.0718373552147797 1.1292222369924527 0.9765787527448798 1.0334472105298396 1.216210347771997 0.9838000648452658 1.0769866292311612 1.0 14.54193336889532 -5.302065645973629 1.4666667429379034 1.0584199907258276 1.1943659129306574 0.3156231440705659 0.06831097194264923 0.6920278673241947 2.4460470740587303 0.02076433746305931 0.10280074668323155 4.988090840546157e-06 5.302065645973629 0.13594592220482982 SMGSQEDDSGNKPSS(ph)YS ddPTM_PC-9_AZD4547_30min_R2 1 SMGSQEDDSGNKPSSYS 17 1 H7C3P9;Q9UNS2-2;Q9UNS2 H7C3P9 COPS3 COP9 signalosome complex subunit 3 1 SMGSQEDDSGNKPS(0.132)S(0.544)YS(0.323) 93.81200000000001 0.0039347 9813100.0 22777.0 23232.0 29698.0 33076.0 32625.0 31614.0 25273.0 31817.0 24531.0 25961.0 True False 30019.612208968796 30741.289673478735 29304.185115671502 25450.839219105877 28095.58189849232 29637.17158236476 27522.24803971162 26900.4137319248 25827.658578970917 25052.113291913403 1.198286621937753 1.2270936713112242 1.1697290673330394 1.015915859973425 1.1214855038820746 1.1830208189235425 1.0985998553900662 1.0737782245543337 1.030957280051414 1.0 14.61264468784683 -1.5228787452847716 0.12526486571893888 0.9622393821044228 1.7838362040581355 0.5804983247323401 0.04981020003339821 71.90077800917561 0.616415348383233 0.333108021228653 10.366936546039533 0.029999999999693706 1.5228787452847716 0.8215968219537126 SMGSQEDDSGNKPSS(ph)YS ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SMGSQEDDSGNKPSSYS 17 1 H7C3P9;Q9UNS2-2;Q9UNS2 H7C3P9 COPS3 COP9 signalosome complex subunit 3 1 SMGSQEDDSGNKPS(0.082)S(0.544)YS(0.374) 96.48700000000001 0.0033585999999999998 3046300.0 17464.0 15399.0 16401.0 19181.0 19249.0 20191.0 19750.0 17085.0 17483.0 12726.0 True False 20420.310270277263 16927.710951554396 16792.06204113887 18106.350755641022 15477.296630102685 19132.14841577593 17879.137022382456 16636.53685305384 17738.655800413508 15033.12306103943 1.3583544940970733 1.1260275647862599 1.1170042294576827 1.2044304222165465 1.0295463269514766 1.2726662542502383 1.1893162152526306 1.106658728562523 1.1799714356350788 1.0 13.87585713309051 -14.52287874528033 0.18638196980981883 0.29323075076397653 1.2021312139946536 0.2903036492984097 0.08579241266889445 187.9005775444904 1.8228866103575871 49.38001237749087 0.24063430210570125 3.0000000000000503e-15 14.52287874528033 0.9089004632306771 SMGSQEDDSGNKPSS(ph)YS ddPTM_PC-9_Lapatinib_30min_R1 3 SMGSQEDDSGNKPSSYS 17 1 H7C3P9;Q9UNS2-2;Q9UNS2 H7C3P9 COPS3 COP9 signalosome complex subunit 3 1 SMGSQEDDS(0.003)GNKPS(0.129)S(0.584)YS(0.285);SMGSQEDDSGNKPS(0.126)S(0.561)YS(0.312);SMGSQEDDSGNKPS(0.187)S(0.453)YS(0.36) 140.96 0.00045492 24435200.0 102474.0 89546.0 81616.0 76593.0 90001.0 81298.0 73996.0 77913.0 93079.0 62316.0 True False 101012.7019685697 89338.6617386899 74905.84752687093 82225.9047267578 84707.318128774 77821.0740548943 77827.15081479136 81533.1224153905 82595.46285467726 73087.23756914947 1.3820840043790044 1.222356525024832 1.024882729436871 1.1250377967694023 1.1589891880730958 1.0647696731083323 1.0648528170346752 1.1155589556692467 1.130094194304879 1.0 16.157331885546945 -4.934260403111005 3.0303959228007806 1.0925127193290127 1.3885423098357343 0.7895120515590199 0.04802751510540068 0.12526692807207632 2.059769100496254 0.012219840534997183 0.07557639510984208 1.1634282282907033e-05 4.934260403111005 0.2960295905067216 SMGTGDTPGLEVPS(ph)SPLR ddPTM_PC-9_AZD4547_30min_R2 2 SMGTGDTPGLEVPSSPLR 18 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 SMGTGDTPGLEVPS(0.5)S(0.5)PLR;SMGTGDTPGLEVPS(0.866)S(0.134)PLR 148.36 9.8784e-05 20160100.0 48469.0 41003.0 77267.0 100198.0 75365.0 73459.0 61902.0 83169.0 61389.0 74870.0 True False 63881.13378217098 54256.41789263293 76242.38909463909 77098.8991436682 64901.87064459383 68865.59711738263 67411.15807993621 70317.1420834915 64633.89721187256 72248.8240886545 0.8841823322104765 0.7509661032829602 1.0552751557739433 1.0671301590882962 0.8983104079999222 0.9531725669732644 0.9330415952129253 0.9732634817309597 0.8946013727858342 1.0 16.14068648625934 -5.257058609045602 24.972155102945283 0.9696179440638559 0.8175742172664092 0.49393306471942255 0.06243074177391747 304.44931640749365 1735467.3364167958 0.01645223173319662 0.04047999048900868 5.532754383762631e-06 5.257058609045602 -0.1520437267974467 SMGTGDTPGLEVPS(ph)SPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SMGTGDTPGLEVPSSPLR 18 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 SMGTGDTPGLEVPS(0.855)S(0.145)PLR;SMGTGDTPGLEVPS(0.562)S(0.438)PLR 157.37 1.1383e-17 6738400.0 31989.2 42801.3 40623.6 40940.8 52062.9 44049.4 45741.0 39989.4 39994.8 38319.5 True False 37404.339744500314 47050.330200062686 41592.22068986094 38647.01970786449 41861.54848165478 41739.371919463156 41408.081343837795 38939.72062227166 40579.64828727209 45266.52201300492 0.8263135332940793 1.0394067869085521 0.9188296082900212 0.8537660502558896 0.9247794312456367 0.9220803822187085 0.9147617157762064 0.8602322177764047 0.896460485203915 1.0 15.466156843030541 -5.512970070313756 24.687536848681788 0.9042573161460888 0.9444246627625229 0.007410056122376996 0.06126665766757397 1068.0295940849821 2660995.527469929 0.015361758809742313 0.028833229840456498 3.0692334993225834e-06 5.512970070313756 0.04016734661643406 SMGTGDTPGLEVPS(ph)SPLR ddPTM_PC-9_Lapatinib_30min_R1 1 SMGTGDTPGLEVPSSPLR 18 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 SMGTGDTPGLEVPS(0.5)S(0.5)PLR 73.953 0.0057574 2232700.0 13274.0 10936.0 12993.0 11152.0 12793.0 13104.0 11043.0 11851.0 12808.0 11468.0 True False 13084.710325846525 10910.678363905845 11924.765694430402 11972.15528198143 12040.54089200572 12543.572466915964 11614.75250618602 12401.640724202534 11365.428165780757 13450.228519850532 0.9728243878187975 0.8111890699703214 0.8865846165238922 0.8901079460703819 0.8951922916577719 0.9325917733221797 0.8635357004562693 0.9220394066836531 0.8449988897219909 1.0 13.715343063978517 -10.756263202579767 3.51094359474698 1.000210170341777 0.8899539134119453 0.36383558443853126 0.04321640315989544 13240783.701407777 19870567.516130857 31654.510091968128 0.010357415038542567 1.7528178910169932e-11 10.756263202579767 -0.11025625692983165 SMGTGDTPGLEVPS(ph)SPLRK ddPTM_PC-9_AZD4547_30min_R2 9 SMGTGDTPGLEVPSSPLRK 19 1 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 SMGTGDTPGLEVPS(0.5)S(0.5)PLRK;SMGTGDTPGLEVPS(0.545)S(0.454)PLRK;SMGTGDTPGLEVPS(0.533)S(0.467)PLRK;SMGTGDTPGLEVPS(0.613)S(0.387)PLRK;SMGTGDTPGLEVPS(0.5)S(0.5)PLRK;SMGTGDTPGLEVPS(0.5)S(0.5)PLRK;SMGTGDTPGLEVPS(0.5)S(0.5)PLRK;SMGTGDTPGLEVPS(0.5)S(0.5)PLRK;SMGTGDTPGLEVPS(0.531)S(0.469)PLRK 180.78 5.7265e-09 582835000.0 535026.0 457593.0 688477.0 890150.0 777628.0 678735.0 606151.0 734480.0 618351.0 663750.0 True False 705153.1387678682 605500.988531171 679347.3451371203 684939.670180406 669667.7750363466 636293.59315355 660097.2647299182 620982.9926713425 651035.7714714142 640512.314529775 1.1009205018728618 0.9453385591433834 1.0606312005661527 1.0693622193403836 1.045518969495498 0.993413520270376 1.0305770080541252 0.9695098417073063 1.0164297495971877 1.0 19.288866782615365 -6.757814545419586 24.99084928717233 1.0018673234402002 1.0411470229685678 0.21596224720212354 0.040131342521801276 162.2208227302361 1118409.213477764 0.01327197458177561 0.012770545418360497 1.7465678217403256e-07 6.757814545419586 0.03927969952836752 SMGTGDTPGLEVPS(ph)SPLRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SMGTGDTPGLEVPSSPLRK 19 1 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 SMGTGDT(0.006)PGLEVPS(0.568)S(0.427)PLRK;SMGTGDT(0.003)PGLEVPS(0.559)S(0.438)PLRK;S(0.001)MGT(0.001)GDT(0.003)PGLEVPS(0.498)S(0.498)PLRK;SMGTGDTPGLEVPS(0.5)S(0.5)PLRK;SMGTGDTPGLEVPS(0.535)S(0.465)PLRK;SMGTGDTPGLEVPS(0.5)S(0.5)PLRK 101.5 0.00037643 322066800.0 257033.0 251234.0 300155.0 311287.0 377962.0 345751.0 316166.0 313168.0 302074.0 279985.0 True False 300543.6102668441 276174.85117233766 307311.8335441772 293846.5985960701 303903.05932291906 327619.208900151 286216.4676363832 304947.6718289238 306491.2607821374 330744.0641399593 0.9086893548591838 0.8350107564000608 0.929152982210842 0.888441034792765 0.9188466015653661 0.990552044379288 0.8653714417540278 0.9220049727026413 0.9266719920707059 1.0 18.33535573914125 -14.522878745267532 0.08484198010270697 1.2839288802335005 0.8296208211919689 0.3789884630569409 0.03764445355635325 254.8437280754459 1.5117291383051426 13.434485901868197 1.0848927810060804 3.0000000000884603e-15 14.522878745267532 -0.4543080590415316 SMGTGDTPGLEVPS(ph)SPLRK ddPTM_PC-9_Lapatinib_30min_R1 11 SMGTGDTPGLEVPSSPLRK 19 1 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 SMGTGDT(0.002)PGLEVPS(0.499)S(0.499)PLRK;SMGTGDTPGLEVPS(0.5)S(0.5)PLRK;SMGTGDTPGLEVPS(0.5)S(0.5)PLRK;SMGTGDTPGLEVPS(0.5)S(0.5)PLRK;SMGTGDTPGLEVPS(0.5)S(0.5)PLRK;SMGTGDTPGLEVPS(0.5)S(0.5)PLRK;SMGTGDTPGLEVPS(0.5)S(0.5)PLRK;SMGTGDTPGLEVPS(0.586)S(0.414)PLRK;SMGTGDTPGLEVPS(0.5)S(0.5)PLRK;SMGTGDT(0.001)PGLEVPS(0.5)S(0.5)PLRK;SMGTGDTPGLEVPS(0.568)S(0.432)PLRK 134.83 1.6515e-05 381204700.0 931680.0 752031.0 894790.0 772813.0 819089.0 810250.0 740441.0 769548.0 850263.0 655286.0 True False 918394.0723508127 750289.7184241476 821223.8201892863 829648.2460485952 770911.7954109327 775597.496285001 778777.411974363 805304.0094530944 754497.4272736766 768551.3119862892 1.194967802445436 0.9762389403578724 1.0685347970675727 1.0794962328597209 1.0030713413507069 1.0091681377532247 1.0133056828198561 1.0478207465052911 0.9817137977732535 1.0 19.551782058460724 -4.75154350565056 24.999719977161366 1.0237326868110348 1.194968147697036 0.7133324724720407 0.03321034459083034 225.00436919561835 568384.3737663825 0.008298272959693223 0.10742859669993825 1.7719705282767465e-05 4.75154350565056 0.17123546088600117 SMGTGDTPGLEVPSS(ph)PLR ddPTM_PC-9_AZD4547_30min_R2 5 SMGTGDTPGLEVPSSPLR 18 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 SMGTGDTPGLEVPS(0.396)S(0.604)PLR;SMGTGDTPGLEVPS(0.047)S(0.953)PLR;SMGTGDTPGLEVPS(0.22)S(0.78)PLR;SMGTGDTPGLEVPS(0.059)S(0.941)PLR;SMGTGDTPGLEVPS(0.042)S(0.958)PLR 150.92 3.6299e-05 92498500.0 164911.1 164473.2 206652.3 294248.0 235415.9 212926.1 186000.5 237079.3 191862.3 216082.9 True False 217349.3994360304 217635.94545127402 203911.95547778567 226413.66968628237 202732.46585922694 199611.79730700812 202554.184169287 200444.1417253396 202003.7494833512 208517.90344151604 1.0423536581212143 1.0437278615373924 0.9779110192088507 1.0858236436747295 0.9722544803740952 0.9572885302052452 0.9713994857333595 0.9612802470055483 0.9687597378898838 1.0 17.66981173387368 -6.385232393423417 9.425599641815229 0.9688301746392813 1.033594554482726 0.5877072357615978 0.026791787720223656 0.2431718297670694 17.5582090867461 0.00790145780517174 0.008957482755686618 4.1187706238280986e-07 6.385232393423417 0.06476437984344474 SMGTGDTPGLEVPSS(ph)PLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SMGTGDTPGLEVPSSPLR 18 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 SMGTGDTPGLEVPS(0.002)S(0.998)PLR;SMGTGDTPGLEVPS(0.002)S(0.998)PLR;SMGTGDTPGLEVPS(0.003)S(0.997)PLR;SMGTGDTPGLEVPS(0.383)S(0.617)PLR;SMGTGDTPGLEVPS(0.153)S(0.847)PLR 156.0 1.2994000000000001e-05 81337000.0 154878.4 174704.7 191766.8 199327.6 217046.4 203611.1 210766.9 198499.4 172183.4 162121.0 True False 181096.25413216354 192048.22803286076 196339.24779163933 188159.92080079849 174517.71600061937 192933.3754791438 190801.53341178634 193289.00107749912 174701.25648601053 191512.25395087036 0.9456118362985854 1.002798641188401 1.0252046213293864 0.9824954639668547 0.9112613548237457 1.0074205253134247 0.9962889030627442 1.0092774592224503 0.9122197294530696 1.0 17.5470771806787 -5.995384286010467 24.994866458653068 0.973461255322959 0.9942786677167387 0.043141621326803214 0.038312212280813884 447.39326561695617 2422670.769456372 0.010915023304482399 0.016128540958662813 1.0106847528235135e-06 5.995384286010467 0.020817412393779655 SMGTGDTPGLEVPSS(ph)PLR ddPTM_PC-9_Lapatinib_30min_R1 8 SMGTGDTPGLEVPSSPLR 18 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 SMGTGDTPGLEVPS(0.204)S(0.796)PLR;SMGTGDTPGLEVPS(0.052)S(0.948)PLR;SMGTGDTPGLEVPS(0.244)S(0.756)PLR;SMGTGDTPGLEVPS(0.063)S(0.937)PLR;SMGTGDTPGLEVPS(0.05)S(0.95)PLR;SMGTGDTPGLEVPS(0.029)S(0.971)PLR;SMGTGDTPGLEVPS(0.021)S(0.979)PLR;SMGTGDTPGLEVPS(0.02)S(0.98)PLR 278.19 9.003899999999999e-92 95468800.0 429494.0 380915.0 440778.0 367832.9 434862.0 427880.0 416529.3 389292.9 475975.5 366674.4 True False 423369.336800446 380033.014720847 404538.93429228367 394884.55852058344 409284.2721315871 409580.5698369969 438095.14906048233 407380.86931760237 422366.1269457827 430053.58147707395 0.9844571816989174 0.883687594033225 0.9406710040708022 0.9182217647491784 0.9517052985022192 0.9523942770811026 1.0186989899160672 0.9472793318413969 0.9821244262054795 1.0 18.71415689452003 -6.808428614453434 2.127071190993193 0.9825094839389138 0.9298785550731498 0.39166860599020914 0.029516153252002658 0.31607531339059913 2.9375751463080597 0.01127665697553403 0.010059814475910181 1.5544307735738177e-07 6.808428614453434 -0.05263092886576404 SMGTGDTPGLEVPSS(ph)PLRK ddPTM_PC-9_AZD4547_30min_R2 3 SMGTGDTPGLEVPSSPLRK 19 1 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 SMGTGDTPGLEVPS(0.235)S(0.765)PLRK;SMGTGDTPGLEVPS(0.468)S(0.532)PLRK;SMGTGDTPGLEVPS(0.24)S(0.76)PLRK 124.04 3.8611999999999996e-05 31275500.0 82019.0 75929.0 111456.0 155092.0 128710.0 116779.0 94641.0 128540.0 96776.0 111091.0 True False 108099.33589881922 100471.5643774778 109978.0206159434 119337.93554751389 110840.83819631992 109476.79066922792 103063.8656560893 108677.09655535132 101891.38178788028 107201.73790346898 1.0083729798873082 0.9372195483243804 1.0258977397826736 1.1132089635988278 1.0339462807601851 1.0212221630941052 0.9614010712111246 1.01376245087753 0.9504638990053457 1.0 16.70996876870631 -7.181043848151897 7.708456233484011 0.9826218986114663 1.0242452405605964 0.18444178626828123 0.04312664521813636 0.5952357050122717 51.093282819005196 0.018204211924421187 0.014077996356933188 6.591073457042562e-08 7.181043848151897 0.04162334194913009 SMGTGDTPGLEVPSS(ph)PLRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SMGTGDTPGLEVPSSPLRK 19 1 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 SMGTGDTPGLEVPS(0.452)S(0.548)PLRK;SMGTGDTPGLEVPS(0.201)S(0.799)PLRK 131.35 1.4944000000000001e-05 287022000.0 131660.0 128069.0 128552.0 152014.0 177609.0 163484.0 156872.0 157835.0 151134.0 133043.0 True False 153947.43759646692 140782.84394146502 131617.1672161749 143497.1484160376 142807.79142687438 154910.61124286632 142011.94850507283 153691.99849000567 153344.04883256278 157162.64273219113 0.9795421794910703 0.8957780391957542 0.8374583484222371 0.91304871133123 0.9086624463946069 0.9856706947008881 0.9035986290143043 0.9779168625453855 0.9757029162067774 1.0 17.261898806855918 -7.5775445172546805 0.6694315119091053 0.9971674558188204 0.902072092205595 0.3712689495668696 0.03997356435623143 0.7849140468243049 0.6884245193814054 0.03780761410739604 0.02115626818427581 2.6451815371096567e-08 7.5775445172546805 -0.09509536361322535 SMGTGDTPGLEVPSS(ph)PLRK ddPTM_PC-9_Lapatinib_30min_R1 1 SMGTGDTPGLEVPSSPLRK 19 1 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 SMGTGDTPGLEVPS(0.366)S(0.634)PLRK 136.35 0.00014319 9179200.0 55138.0 38771.0 41713.0 39609.0 37685.0 43957.0 36893.0 35726.0 45240.0 35122.0 True False 54351.722008929166 38681.22813158316 38283.518156836406 42521.97799175056 35468.44239156065 42077.06157877178 38803.13902116462 37385.96038417515 40144.59480168033 41192.79090287672 1.3194474279996766 0.9390290699842296 0.9293742258712279 1.0322674686453697 0.861035186355477 1.0214666366738776 0.941988590009685 0.9075850304079369 0.9745538945475242 1.0 15.330104254853392 -4.760053537711075 24.99999952306604 0.9536130250565205 1.3194478720026708 0.8258453714959613 0.05000548709943554 12.735389404512713 229657.90812378068 0.011568134258746032 0.07046396313766805 1.7375866143207817e-05 4.760053537711075 0.3658348469461503 SMGY(ph)DDLDYGMMSDYGTAR ddPTM_PC-9_Lapatinib_30min_R1 1 SMGYDDLDYGMMSDYGTAR 19 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 S(0.112)MGY(0.873)DDLDY(0.01)GMMS(0.004)DYGTAR 58.11600000000001 0.009877200000000001 13688000.0 60866.0 67390.0 51597.0 52861.0 64897.0 61627.0 47676.0 51150.0 68132.0 49087.0 True False 59998.03967854263 67233.96259542914 47354.89383017973 56748.57427912668 61079.88605241106 58991.356869553616 50144.42999954037 53526.61573225546 60458.25669823357 57571.62254568388 1.0421460612984002 1.1678316438290073 0.8225388088133693 0.985703924430754 1.0609373742062476 1.0246603145975808 0.870992127410515 0.9297395724739449 1.050139878379476 1.0 15.81307025196762 SMGYDDLDY(ph)GMMSDYGTAR ddPTM_PC-9_AZD4547_30min_R2 1 SMGYDDLDYGMMSDYGTAR 19 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 S(0.001)MGYDDLDY(0.969)GMMS(0.027)DY(0.002)GTAR 110.98 5.3673999999999995e-05 11014000.0 23405.0 28280.0 30357.0 31823.0 37952.0 51590.0 36379.0 50272.0 41104.0 31229.0 True False 30847.30314575733 37420.95695445844 29954.446345088545 24486.699010448865 32683.019899205527 48364.069144499175 39616.660524538784 42503.61753563577 43276.673524520855 30135.682215367822 1.0236138981458536 1.2417491227517476 0.9939860040670705 0.8125483549850339 1.0845289536049951 1.6048771950427494 1.3146097122147145 1.4104083402485863 1.4360608535502717 1.0 14.879185104623454 -6.610936272903642 7.911177145457754 1.3754051582287725 1.022023151495844 0.4681530959061728 0.17183816341376873 0.2054370763628011 16.098949509941615 0.055769835352281985 0.055732518654359194 2.449422636557355e-07 6.610936272903642 -0.3533820067329285 SMGYDDLDY(ph)GMMSDYGTAR ddPTM_PC-9_Lapatinib_30min_R1 1 SMGYDDLDYGMMSDYGTAR 19 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 S(0.285)MGY(0.01)DDLDY(0.649)GMMS(0.043)DY(0.007)GT(0.005)AR 66.538 0.010272 8426000.0 14501.0 14348.0 12871.0 10439.0 12220.0 13032.0 12562.0 11808.0 14307.0 10419.0 True False 14294.21308084229 14314.778087538494 11812.796063496779 11206.718883483158 11501.243625444371 12474.651739075769 13212.398893661937 12356.642787223316 12695.595000610967 12219.910267555171 1.1697477942039032 1.17143070399996 0.9666843540464194 0.9170868392739252 0.941188877301422 1.020846427342184 1.0812189782393002 1.01118932272614 1.0389270234102108 1.0 13.576946070841242 -5.255477442299994 24.509125207012424 0.9965341383562687 1.170589282472124 0.7058886506214631 0.04478164005841113 220.13108376707913 904934.8195876082 0.013318861884339806 0.033308304022936226 5.552934588812667e-06 5.255477442299994 0.17405514411585532 SMGYDDLDYGMMS(ph)DYGTAR ddPTM_PC-9_AZD4547_30min_R2 1 SMGYDDLDYGMMSDYGTAR 19 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 S(0.049)MGY(0.002)DDLDY(0.251)GMMS(0.691)DY(0.007)GT(0.001)AR 77.67399999999999 0.0019959 11635000.0 12715.0 18882.0 17909.0 18406.0 17481.0 27491.0 23312.0 27637.0 23822.0 20648.0 True False 16758.105511570364 24985.23724236508 17671.51495846727 14162.78106986526 15054.064894024345 25771.98342414087 25386.722838671983 23366.33668508049 25081.182286423125 19925.119804762064 0.8410541906787035 1.2539566881998703 0.8868962963145552 0.710800296743028 0.7555319637489183 1.2934418300451784 1.2741064087657132 1.1727074624412537 1.2587719688605723 1.0 14.282300778355735 -6.768825587629507 24.99963564157513 1.215243585652674 0.8997984149552768 0.4933831105394071 0.15658617940465497 156.74603386668596 530525.0725152887 0.05822233590308261 0.052363526855292816 1.7028422313839807e-07 6.768825587629507 -0.3154451706973972 SMIIDRR ddPTM_PC-9_AZD4547_30min_R2 1 SMIIDRR 7 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 88.64299999999999 0.010841 3468700.0 16348.0 10874.0 20394.0 35165.0 22583.0 16550.0 16215.0 19656.0 18914.0 15216.0 False True 21546.323940475995 14388.80784734021 20123.562234797133 27058.252543834165 19447.740260954844 15515.125883726727 17658.10358738274 16618.616849945436 19913.75542630371 14683.292471389948 1.4674041249575667 0.9799442376685246 1.3705074848851115 1.842791907643094 1.324480888659564 1.0566516953849137 1.202598369663285 1.131804524245936 1.356218672692463 1.0 13.841887883122329 -6.546225994033509 12.668702754310344 1.164231157078362 1.4062029484598852 0.25811845578355597 0.213366913152702 1.6484556266818537 889.982921825805 0.0744479395536237 0.07463409626125493 2.842981318872621e-07 6.546225994033509 0.24197179138152336 SMIIDRR ddPTM_PC-9_Lapatinib_30min_R1 1 SMIIDRR 7 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 97.602 0.007866199999999999 2919500.0 11049.0 14038.0 18614.0 15144.0 16272.0 16712.0 12486.0 12731.0 17265.0 11489.0 False True 10891.439233861558 14005.495873492144 17083.628772117867 16257.740278903053 15314.912951982878 15997.266717574754 13132.463985532793 13322.528736800485 15320.433891490078 13474.858341869789 0.8082785701738403 1.0393798226415139 1.2678150922770532 1.2065240217320985 1.1365546533721675 1.1871936840973834 0.9745901331464769 0.9886952722466864 1.1369643748970346 1.0 13.71798248588113 -7.2690702163747085 24.790970925104645 1.0241203877797256 1.1176141422345358 0.09255019837982936 0.12429730630734767 1340.143980324766 4353821.636262931 0.05474010018082257 0.037748480346256885 5.3818276253532586e-08 7.2690702163747085 0.09349375445481023 SMLEVPRS(ph)IS(ph)VPPS(ph)PSDIPPPGPPR ddPTM_PC-9_AZD4547_30min_R2 1 SMLEVPRSISVPPSPSDIPPPGPPR 25 1 H0YDE2;A0A1B0GTN9;E9PKC0;Q6IQ23-3;Q6IQ23;Q6IQ23-2 H0YDE2 PLEKHA7 Pleckstrin homology domain-containing family A member 7 3 S(0.369)MLEVPRS(0.901)IS(0.733)VPPS(0.933)PS(0.064)DIPPPGPPR 43.256 0.042538 0.0 3482.2 2079.8 4164.0 7001.1 4980.0 3460.2 4854.7 5570.2 3374.7 2945.8 True False 4589.467165740491 2752.054677294294 4108.782639290732 5387.104560916743 4288.612961057217 3243.8331470012818 5286.758895199938 4709.453580462257 3553.0797524134045 2842.6684386317374 1.6144926025736368 0.9681236966977905 1.4453963689372136 1.8950871961380484 1.5086574652095046 1.1411225814863717 1.8597873826412958 1.6567016808787802 1.2499100155780425 1.0 11.473030121336011 -8.520392481149024 4.860114402043576 1.0005360606438856 1.501624901932958 0.26686357493257373 0.27168888855677675 0.21752034254989605 19.011556357268883 0.27196157027122714 0.07080098624227246 3.017223758723506e-09 8.520392481149024 0.5010888412890724 SMMS(ph)PMADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SMMSPMADR 9 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 S(0.049)MMS(0.951)PMADR 70.056 0.024182 5631000.0 14401.0 12698.0 16928.0 18490.0 18048.0 17544.0 15856.0 13732.0 13822.0 13590.0 True False 16838.804867284856 13958.573521841528 17331.627719797507 17454.065245388796 14511.623958652046 16623.961755553104 14354.004892501078 13371.549550256666 14024.120601345054 16053.7594216192 1.0489010346454086 0.8694893921883409 1.0795993178057368 1.087226037652205 0.9039392940640185 1.0355183056478365 0.8941210912361683 0.8329232548638752 0.8735723660128555 1.0 13.970623562493552 -7.298336359546695 9.507539708789174 0.886066342741636 1.000633657953754 0.2952220003799625 0.0773654197982752 0.6145570966077336 153.92559177442183 0.031953844150142845 0.021637306972409807 5.031108003118061e-08 7.298336359546695 0.11456731521211805 SMMS(ph)PMADR ddPTM_PC-9_Lapatinib_30min_R1 1 SMMSPMADR 9 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 S(0.018)MMS(0.982)PMADR 74.301 0.017263999999999998 1829100.0 16712.0 12160.0 19222.0 14806.0 12969.0 14934.0 13940.0 12325.0 17774.0 14210.0 True False 16473.68381539454 12131.844267108165 17641.641359065754 15894.88263136811 12206.188918035032 14295.307632854317 14661.744991056144 12897.664494624602 15772.10495148245 16666.17956636518 0.988449917378838 0.7279319305782607 1.0585294181438678 0.9537208313443555 0.7323927400055698 0.8577435263990775 0.879730410480259 0.7738824871810454 0.9463539552467619 1.0 14.024635808868135 -4.445410519650625 21.78160366316199 0.8753892928850981 6.494767627568483 0.08174557047507269 0.1063322560073313 923.2904732336821 256849.70240787588 0.025074768785448932 2701.9602090668204 3.5858282167876996e-05 4.445410519650625 5.619378334683384 SMPEQTGEK ddPTM_PC-9_Lapatinib_30min_R1 1 SMPEQTGEK 9 0 P62888;A0A0C4DH44;A0A0B4J213 P62888 RPL30 60S ribosomal protein L30 0 90.15 0.040525 2934400.0 17542.0 16454.0 18541.0 16136.0 19174.0 17064.0 17266.0 15409.0 18515.0 18937.0 False True 17291.84786319118 16415.90177393074 17016.630550329734 17322.695268118052 18046.223017534398 16334.212498126844 18159.948996813167 16124.958393320128 16429.645728406518 22210.235218033602 0.7785531172200761 0.7391142692897663 0.7661616539978414 0.7799419996260503 0.8125183205120567 0.7354362679087828 0.8176387516179116 0.7260147510832063 0.739733081037632 1.0 14.438937051411996 -10.572015803969428 4.509197011161767 1.0000110815000092 0.7665341956072866 0.8435540259253264 0.03021528828618584 42198685.01140024 11771.950075622235 5274.529910431377 0.0072033167336486995 2.6790708316993418e-11 10.572015803969428 -0.23347688589272253 SMS(ph)AAFCSLLAPER ddPTM_PC-9_AZD4547_30min_R2 3 SMSAAFCSLLAPER 14 0 E9PNR2;Q13671-2;Q13671 E9PNR2 RIN1 Ras and Rab interactor 1 1 S(0.213)MS(0.787)AAFCSLLAPER;S(0.393)MS(0.607)AAFCSLLAPER;S(0.261)MS(0.739)AAFCSLLAPER 142.54 0.00015158 184535000.0 137177.0 127973.0 159861.0 217072.0 187239.0 161300.0 152714.0 181924.0 137065.0 172225.0 True False 180796.43254114717 169337.76960158814 157741.13868867804 167029.40412896845 161244.0968304001 151213.8855012158 166305.25015378167 153811.8259976329 144309.97607625643 166195.45517121037 1.0878542518199144 1.0189073427257118 0.9491302787201797 1.0050178806448045 0.970207618880375 0.9098557198537051 1.0006606376958875 0.9254875582438752 0.8683148159953707 1.0 17.34252140473034 -1.522878751001876 0.5310392320783603 0.9412461852206703 6.670194263228112 0.5246925971947518 0.041133031892170345 97.9262401419768 0.9512026248017624 0.02111664217698485 634.9478399075948 0.02999999960477013 1.522878751001876 5.728948078007441 SMS(ph)AAFCSLLAPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SMSAAFCSLLAPER 14 0 E9PNR2;Q13671-2;Q13671 E9PNR2 RIN1 Ras and Rab interactor 1 1 S(0.012)MS(0.988)AAFCSLLAPER;S(0.066)MS(0.934)AAFCSLLAPER;S(0.047)MS(0.953)AAFCS(0.001)LLAPER;S(0.021)MS(0.979)AAFCSLLAPER;S(0.294)MS(0.705)AAFCS(0.001)LLAPER;S(0.111)MS(0.786)AAFCS(0.102)LLAPER 158.89 2.6071999999999997e-05 244912000.0 451620.0 388818.0 455108.0 426146.0 498237.0 420386.0 446640.0 429006.0 456455.0 337782.0 True False 528070.3460984086 427417.2814313587 465959.5007267021 402270.42120397225 400611.03647423116 398340.21811274247 404331.0258064262 417745.04706943 463129.79084698035 399019.202719159 1.3234208842577417 1.0711697044119128 1.1677620965391422 1.0081480251142236 1.003989366286696 0.9982983660891769 1.013312199139964 1.046929682137255 1.1606704331293654 1.0 18.60609865196482 -1.522878745280424 0.9398043667925644 1.0374710483565557 183.0291499726687 0.651595627780848 0.059931969147887544 730.180950400894 1.3474701770456896 0.02026169695550466 285527.3178381144 0.029999999999994028 1.522878745280424 181.99167892431214 SMS(ph)AAFCSLLAPER ddPTM_PC-9_Lapatinib_30min_R1 7 SMSAAFCSLLAPER 14 0 E9PNR2;Q13671-2;Q13671 E9PNR2 RIN1 Ras and Rab interactor 1 1 S(0.307)MS(0.69)AAFCS(0.002)LLAPER;S(0.341)MS(0.659)AAFCSLLAPER;S(0.002)MS(0.998)AAFCSLLAPER;S(0.013)MS(0.987)AAFCSLLAPER;SMS(1)AAFCSLLAPER;S(0.001)MS(0.999)AAFCSLLAPER;S(0.002)MS(0.998)AAFCSLLAPER 151.22 5.7008e-05 198310700.0 275627.0 225063.0 263455.0 237484.0 232529.0 243654.0 224305.0 196566.0 238596.0 157631.6 True False 271696.5084361993 224541.880451329 241794.74686570934 254949.3655833999 218852.10138960354 233233.48640521566 235918.41536720574 205699.17395946253 211722.8059527349 184878.0120290962 1.4695988206182116 1.2145407557497454 1.3078610279931806 1.3790139929851466 1.183764899825732 1.261553409436863 1.2760761151524973 1.1126210829608525 1.1452027400609104 1.0 17.496214126313106 -7.850768464064047 0.17855621202445315 0.8888449609933232 1.478838260291565 0.6868407337313895 0.07183620623421919 2.0337070929279046 0.3736869353173951 0.4790786962923291 0.5158662276786747 1.4100403345584168e-08 7.850768464064047 0.5899932992982418 SMS(ph)AEDLLER ddPTM_PC-9_AZD4547_30min_R2 2 SMSAEDLLER 10 0 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 S(0.008)MS(0.992)AEDLLER;S(0.011)MS(0.989)AEDLLER 108.35 0.0017971 18116900.0 44267.0 51996.0 69404.0 96557.0 86179.0 87486.0 80194.0 90839.0 87105.0 86268.0 True False 58342.985189200546 68802.69016280143 68483.65761223192 74297.27544077899 74214.53340782117 82015.4865899528 87331.11064363671 76801.9198225578 91709.19247161811 83247.78357793545 0.7008352977299466 0.8264807446601781 0.8226484197998911 0.8924835262577638 0.8914896015020332 0.9851972396739068 1.049050279661542 0.9225701456742915 1.101641251334472 1.0 16.345124241358718 -5.427831003768633 0.452580309243534 1.034892621218719 0.6183501956487228 0.8117169462105365 0.049116021754578 1.1853590959817824 0.28897524448234946 0.037203806872882605 0.24998140818082146 3.73395428221514e-06 5.427831003768633 -0.4165424255699962 SMS(ph)AEDLLER ddPTM_PC-9_Lapatinib_30min_R1 2 SMSAEDLLER 10 0 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 S(0.048)MS(0.952)AEDLLER;S(0.003)MS(0.997)AEDLLER 96.06700000000001 0.0049964 9976200.0 55157.0 51233.0 61233.0 49371.0 50126.0 58642.0 52280.0 52683.0 62991.0 51524.0 True False 54370.451065445035 51114.37313624614 56198.6591062154 53001.90803682796 47177.68723150772 56134.01836117872 54986.802591995416 55130.84450874712 55896.290255363536 60429.854748585494 0.8997283096517406 0.8458463676423547 0.9299817009328631 0.8770815064398049 0.7807016486765928 0.9289120186490714 0.9099277636983318 0.9123113854586518 0.9249780673462883 1.0 15.882973853876505 -8.5539741964009 0.6340223867001851 0.9997894596932371 0.8734074285087252 0.45572896877666136 0.040602864164170555 0.821586002580949 0.7607704580501037 0.04287394318771498 0.0177949665789604 2.7927097651103054e-09 8.5539741964009 -0.12638203118451186 SMS(ph)APGNLLVK ddPTM_PC-9_AZD4547_30min_R2 2 SMSAPGNLLVK 11 0 J3KPJ3;Q8N5S9 J3KPJ3 CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 1 S(0.007)MS(0.993)APGNLLVK;S(0.255)MS(0.745)APGNLLVK 81.789 0.014666 13482200.0 89948.0 65029.0 71550.0 101590.0 91222.0 63950.0 63938.0 88188.0 73744.0 79305.0 True False 118549.59296537426 86048.35253859546 70601.20025006059 78169.99504985397 78557.39990633776 59951.19639059362 69628.35813568166 74560.57095863798 77641.95728864023 76528.55608856323 1.5490896343082952 1.1243953490905456 0.9225471361089949 1.021448712025759 1.026510938157864 0.7833833467498676 0.9098349909425147 0.9742843033958751 1.0145488332327675 1.0 16.223710559251224 -4.7514487061276895 2.1777923077514876 0.9518518221270613 1.7392515865998932 0.866899292627999 0.07012236521296485 0.25247095996846014 1.2939112752766837 0.019707059693128123 0.40359501095270245 1.772357363253567e-05 4.7514487061276895 0.7873997644728319 SMS(ph)APGNLLVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SMSAPGNLLVK 11 0 J3KPJ3;Q8N5S9 J3KPJ3 CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 1 S(0.011)MS(0.989)APGNLLVK;S(0.01)MS(0.99)APGNLLVK 104.41 0.0023655 20323000.0 126948.0 123405.0 117193.0 105694.0 102838.0 93912.0 81147.0 106222.0 79136.0 64563.0 True False 148437.78906270937 135655.83284476693 119987.3255769275 99772.30784457111 82687.63212875974 88987.08939737253 73460.16870659596 103433.78505151226 80293.21428939672 76267.76081957325 1.9462717597527068 1.7786785843324828 1.5732378174938384 1.3081845693700462 1.0841754266835497 1.1667720205905798 0.9631876944752683 1.3561927600864763 1.052780538284669 1.0 16.218785723178758 -5.559971836038948 1.2506678989255908 1.1099296505349814 1.9499890816729772 0.8964210919776197 0.10420295728486027 0.15886469414714674 0.4528939681166783 0.034052160125072076 0.12015991582515599 2.754407320632235e-06 5.559971836038948 0.8400594311379959 SMS(ph)APGNLLVK ddPTM_PC-9_Lapatinib_30min_R1 1 SMSAPGNLLVK 11 0 J3KPJ3;Q8N5S9 J3KPJ3 CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1 1 SMS(1)APGNLLVK 123.28 0.00058666 6580000.0 75986.0 45575.0 60229.0 44476.0 39712.0 33811.0 29860.0 35140.0 40824.0 48914.0 True False 74902.42570587425 45469.473887619664 55277.20411066337 47746.91340758665 37376.218236795976 32364.982347290592 31406.00469389789 36772.732684877 36225.97122422189 57368.71972619191 1.3056318157938125 0.7925830331343512 0.9635425781591279 0.8322813135010161 0.6515086691002401 0.5641573056146525 0.5474412684088427 0.6409892509434593 0.6314585962022573 1.0 15.807976701874635 -1.5228788720091597 0.578793818752369 0.6533883570521645 33.597053941781475 0.5830123071630003 0.14699182372009154 103.91750618162118 0.8661264074759756 0.06790627738948017 4300.512395653518 0.029999991245884376 1.5228788720091597 32.94366558472931 SMS(ph)ASVHPNK ddPTM_PC-9_AZD4547_30min_R2 1 SMSASVHPNK 10 0 E9PC69;Q7KZI7-14;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 S(0.126)MS(0.857)AS(0.017)VHPNK 89.35600000000001 0.0082787 2511500.0 6310.3 6202.7 23143.0 45756.0 35374.0 32494.0 16453.0 38054.0 20010.0 27422.0 True False 8316.844137606171 8207.6014745905 22836.108698632426 35207.661123153004 30462.930699686338 30462.145043251712 17917.285126315634 32173.628693926716 21067.687748775345 26461.9641266072 0.3142942866150922 0.31016599657233496 0.8629785978611838 1.3305006746552162 1.1511968859883766 1.1511671959611787 0.6770958134698705 1.2158443167707458 0.7961498114039096 1.0 14.691632528488437 -5.339905487750166 3.6762461711006966 1.0507773071267454 0.3017260940201863 0.710698465861292 0.18401339603103364 0.11631884526424956 2.988235740313703 0.0494237990252619 0.11781083236584787 4.571876731128408e-06 5.339905487750166 -0.7490512131065592 down SMS(ph)DVSAEDVQNLR ddPTM_PC-9_AZD4547_30min_R2 1 SMSDVSAEDVQNLR 14 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;E9PJ10;E9PK58;E9PLU6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.016)MS(0.983)DVSAEDVQNLR 92.265 0.018316 0.0 13644.0 13183.0 15460.0 22246.0 18659.0 13525.0 10050.0 17158.0 14203.0 13216.0 True False 17982.508187169962 17444.14694238422 15254.990298615452 17117.528397273847 16068.519927784459 12679.279611927723 10944.43053057024 14506.62535161599 14953.741584000818 12753.311862637333 1.4100265390554994 1.3678130928084153 1.1961591203071844 1.3422026044405075 1.2599487961130713 0.99419505682077 0.858163796859193 1.1374790727195532 1.172537905844674 1.0 13.638584323681211 -6.6724264505856485 4.60271576320356 1.0303767759443831 1.319461147811583 0.6907044186666147 0.09521858765259265 0.13590564883832157 5.100862489550081 0.0348371159664549 0.034417449726650624 2.1260503694078556e-07 6.6724264505856485 0.2890843718671998 SMS(ph)DVSAEDVQNLR ddPTM_PC-9_Lapatinib_30min_R1 2 SMSDVSAEDVQNLR 14 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;E9PJ10;E9PK58;E9PLU6;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.083)MS(0.917)DVSAEDVQNLR;S(0.102)MS(0.898)DVSAEDVQNLR 122.1 5.5211000000000004e-05 11972600.0 38489.0 41260.0 38970.0 36151.0 36962.0 44957.0 44559.0 40980.0 40407.0 38225.0 True False 37940.13980198184 41164.46500500687 35766.03702855022 38809.66513620077 34787.96783008794 43034.29390988559 46866.04699113852 42884.08040484517 35855.938155426535 44832.140318389145 0.8462709906896779 0.9181909387476226 0.7977767015928032 0.8656661239142738 0.7759604512082304 0.9598982695063052 1.0453671553110104 0.9565476932462016 0.7997819845491344 1.0 15.452245755873523 -6.784048978102194 24.956907752767776 0.9554188120128136 0.8440683009771464 0.3971126877073705 0.06860716582968546 252.60494928296907 278828.17407154775 0.024669699155928468 0.021771799163460125 1.6441862875982406e-07 6.784048978102194 -0.11135051103566729 SMS(ph)ENAVR ddPTM_PC-9_AZD4547_30min_R2 5 SMSENAVR 8 0 Q9GZY8-5;C9JHF5;H7C433;A0A0A0MS29;Q9GZY8-4;Q9GZY8-3;Q9GZY8-2;Q9GZY8 Q9GZY8-5 MFF Mitochondrial fission factor 1 S(0.31)MS(0.69)ENAVR;S(0.29)MS(0.71)ENAVR;S(0.003)MS(0.997)ENAVR;S(0.002)MS(0.998)ENAVR;S(0.082)MS(0.918)ENAVR 93.561 0.0071324 227669000.0 1194129.0 1060099.0 1548622.0 1740398.0 1333099.0 1241692.0 1383238.0 1891363.0 1333926.0 1414098.0 True False 1573837.182573812 1402755.2703841727 1528086.2604283595 1339176.129981059 1148021.2148137393 1164048.8029496334 1506343.5023129282 1599096.3075479895 1404434.6050960966 1364590.8594379341 1.1533399712365544 1.0279676583514257 1.1198127628216474 0.9813755681557598 0.8412933494854286 0.8530386928057669 1.1038792264322956 1.1718503729437604 1.029198309062816 1.0 20.380037027033666 -10.581827001314526 15.025414750426014 0.9999909707592408 1.0277789813200715 0.0064703262272209905 0.10874280599319237 0.0 0.0 0.11676398932251224 0.028319427132071223 2.6192261539716058e-11 10.581827001314526 0.02778801056083069 SMS(ph)ENAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SMSENAVR 8 0 Q9GZY8-5;C9JHF5;H7C433;A0A0A0MS29;Q9GZY8-4;Q9GZY8-3;Q9GZY8-2;Q9GZY8 Q9GZY8-5 MFF Mitochondrial fission factor 1 S(0.015)MS(0.985)ENAVR 75.229 0.026667000000000003 6575700.0 13573.0 19097.0 25469.0 17403.0 24860.0 18513.0 19661.0 18308.0 18897.0 19039.0 True False 15870.640821030298 20992.823952323797 26076.27755172038 16427.966331287258 19988.861459003212 17542.145689726098 17798.567746686665 17827.43439892945 19173.332875388325 22490.619987358932 0.7056559948080819 0.9334035239634574 1.1594290226937631 0.7304363481540639 0.8887643591078478 0.7799760833443377 0.7913773722863363 0.7926608696847632 0.8525035275223574 1.0 14.457035811245863 SMS(ph)ENAVR ddPTM_PC-9_Lapatinib_30min_R1 2 SMSENAVR 8 0 Q9GZY8-5;C9JHF5;H7C433;A0A0A0MS29;Q9GZY8-4;Q9GZY8-3;Q9GZY8-2;Q9GZY8 Q9GZY8-5 MFF Mitochondrial fission factor 1 S(0.294)MS(0.706)ENAVR;S(0.018)MS(0.982)ENAVR 107.11 0.0038152 116062000.0 883348.0 917300.0 740660.0 598490.0 592510.0 618410.0 613167.0 553558.0 984314.0 427016.0 True False 870751.2955338166 915176.0482087426 679765.7938302803 642504.9511041137 557659.7267194804 591962.045884119 644913.7870108272 579278.3255428327 873450.1920340656 500825.1466369454 1.738633336167194 1.8273364553560756 1.357291658366051 1.2828927529269487 1.1134818817788616 1.1819734888696392 1.2877024872681433 1.1566478429302174 1.7440222359027049 1.0 18.933947476838355 -5.348851151146229 3.624003828387629 1.2551055875080557 1.788078581930336 0.5558412144495095 0.18649077454208582 0.16236670120964253 3.981254227493179 0.04852096851859662 0.11526950685219377 4.478667784582271e-06 5.348851151146229 0.5329729944222803 SMS(ph)FQGIR ddPTM_PC-9_AZD4547_30min_R2 2 SMSFQGIR 8 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 S(0.008)MS(0.992)FQGIR;S(0.002)MS(0.998)FQGIR 128.03 0.0036637 11986800.0 31371.0 26502.0 29280.0 39691.0 39779.0 34210.0 20675.3 31188.0 29161.0 25068.4 True False 41346.32544266409 35068.25322514348 28891.728068787856 30540.853169837086 34256.3724855211 32070.843291981324 22515.361646636695 26368.61122894272 30702.390926638578 24190.762946227114 1.7091782319793525 1.4496547009739047 1.1943289317914598 1.262500618013801 1.416093099736809 1.3257474914400422 0.930742105847814 1.0900280940934635 1.2691782807712992 1.0 14.562168650371248 -1.5228787452803376 0.3438647835547348 1.097811302808155 7.4526055624328125 0.6311906582246299 0.13242648439547547 44.332221714730494 0.6267261539334119 0.12445308949971058 181.56396261242543 0.029999999999999995 1.5228787452803376 6.354794259624658 SMS(ph)FQGIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SMSFQGIR 8 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 S(0.012)MS(0.988)FQGIR;S(0.226)MS(0.774)FQGIR;S(0.003)MS(0.997)FQGIR 80.916 0.029245999999999998 80840000.0 302670.3 289591.6 275209.0 279975.8 261929.1 228784.2 221108.5 219220.1 215994.4 182876.4 True False 353906.40377908177 318340.3402037906 281771.0262959453 264289.66361978994 210605.97312877732 216786.3538004339 200163.5021930865 213465.8046578955 219152.9094787411 216030.4436712143 1.6382246768779802 1.4735901792077322 1.304311658614118 1.2233908292204563 0.974890249493295 1.0034990907594952 0.9265522895362083 0.9881283444604593 1.0144538230559716 1.0 17.720875110152434 -5.4790656799456405 0.8916621605978973 0.9688216001430358 1.6986342151368417 0.9679547100009507 0.041644088584772025 0.1542620297944245 0.18645972962646828 0.016953318457060097 0.08990316777898791 3.318442677331103e-06 5.4790656799456405 0.7298126149938059 SMS(ph)FQGIR ddPTM_PC-9_Lapatinib_30min_R1 4 SMSFQGIR 8 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 S(0.008)MS(0.992)FQGIR;S(0.002)MS(0.998)FQGIR;S(0.007)MS(0.993)FQGIR;S(0.002)MS(0.998)FQGIR 108.47 0.0037935000000000004 47544100.0 67677.0 59532.0 68971.0 58994.0 63687.0 66541.0 51599.4 55274.0 64576.0 68044.0 True False 66711.91356955832 59394.15731163518 63300.47061575923 63332.615558214886 59941.05587345957 63695.196544647006 54270.964454196794 57842.231827657655 57302.77086457359 79805.31473706907 0.8359332180989577 0.7442381188185072 0.7931861533822955 0.7935889453838252 0.751091027846261 0.7981322641794054 0.6800419825797425 0.7247917261930213 0.7180320139500285 1.0 16.284197207319032 -10.786586339902367 5.80578579004289 1.0000128074791779 0.758887546167034 0.7300717449092882 0.04379552350323271 7.4990476798323526e-06 9.510816151268922e-07 0.04379910605999268 0.010622279573539135 1.634608150597229e-11 10.786586339902367 -0.24112526131214385 SMS(ph)IDDTPR ddPTM_PC-9_AZD4547_30min_R2 1 SMSIDDTPR 9 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GUE9;Q96N67-7;A0A0C4DGY6;A0A1B0GVW2 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 S(0.053)MS(0.947)IDDTPR 81.771 0.014747 6117200.0 47954.0 45483.0 46122.0 68086.0 52963.0 44368.0 42209.0 72453.0 47541.0 50610.0 True False 63202.3744948364 60184.49028145801 45510.392144420555 52389.82461821388 45610.00165792636 41593.66194617445 45965.51923033226 61257.05365430897 50053.92020312487 48838.1593044851 1.294118684956911 1.2323251150034826 0.9318613312324623 1.072723160829745 0.9339009149293986 0.8516631776979082 0.9411804188556093 1.254286699717681 1.0248936674918483 1.0 15.57572120615785 -5.1624551702422545 4.9917562681217165 1.003375035299606 1.2774109968090164 0.510601340874885 0.10298057738749583 0.19009894173680356 7.393186670913299 0.028661891122693267 0.08121170274871649 6.879309198534916e-06 5.1624551702422545 0.27403596150941034 SMS(ph)IDDTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SMSIDDTPR 9 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GUE9;Q96N67-7;A0A0C4DGY6;A0A1B0GVW2 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 S(0.373)MS(0.627)IDDTPR 114.97 0.00077387 0.0 104940.0 157070.0 97196.0 136980.0 151460.0 127630.0 162730.0 117650.0 130890.0 104660.0 True False 122704.26934052321 172662.8715605334 99513.52125788278 129305.45469515184 121782.5002647076 120936.85812022584 147315.03633682488 114561.81216047911 132804.0186304483 123634.02951189603 0.9924797389922217 1.3965642974042176 0.8049039706200598 1.045872687363232 0.9850241130658103 0.978184231296848 1.191541171297424 0.9266203860924552 1.0741704298950308 1.0 16.915716365340877 -5.261755991178822 24.999999732431192 1.0052212034497834 1.1945219988217302 0.2602639417341005 0.1304741899595722 34.923369935455895 2757869.206364801 0.031544622618171196 0.07312598925416156 5.473233907565806e-06 5.261755991178822 0.18930079537194677 SMS(ph)IDDTPR ddPTM_PC-9_Lapatinib_30min_R1 3 SMSIDDTPR 9 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GUE9;Q96N67-7;A0A0C4DGY6;A0A1B0GVW2 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 S(0.058)MS(0.935)IDDT(0.007)PR;S(0.013)MS(0.987)IDDTPR;S(0.174)MS(0.826)IDDTPR 131.09 0.001245 11370300.0 113377.0 105275.0 143521.0 110036.0 112545.0 106866.0 105791.0 100483.0 130773.0 138923.0 True False 111760.22318920473 105031.24220557687 131721.25738708142 118128.41450933523 105925.32437198333 102295.59029681337 111268.34034066154 105151.8070112265 116043.96763926042 162935.65544673867 0.6859163077767072 0.6446179132345288 0.8084250008135219 0.725000394698444 0.650105246034431 0.6278281448976791 0.68289742988166 0.6453578667168962 0.712207327003349 1.0 17.313942819905165 -8.574315490021835 19.785240491695536 1.0000000004314942 0.6845901233152986 0.783856514637961 0.04951844861973231 1121.2561577861798 431293.2971083816 0.051265036023733515 0.013236575375669093 2.6649220482281537e-09 8.574315490021835 -0.3154098771161956 SMS(ph)LDMGQPSQANTK ddPTM_PC-9_AZD4547_30min_R2 2 SMSLDMGQPSQANTK 15 0 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 S(0.133)MS(0.867)LDMGQPSQANTK;S(0.16)MS(0.84)LDMGQPSQANTK 114.01 0.000109 16619300.0 56791.0 57300.0 54776.0 62723.0 56761.0 49934.0 47646.0 66728.0 55384.0 55548.0 True False 74849.35667381769 75821.10443742806 54049.63444999739 48263.18141068986 48880.71491617844 46811.6190862846 51886.40169746765 56416.72085689657 58311.48517132308 53603.28142749535 1.3963577355811718 1.4144862481970417 1.008326971980359 0.9003773673067275 0.9118978095080853 0.8732976384963063 0.9679706226129089 1.0524863283455272 1.0878342448157046 1.0 15.710033700274813 -5.284738868280427 4.983625289189694 0.9660294507547867 1.4101123487834981 0.8806688088636712 0.0633794313357696 0.05779494227826548 4.15368388793271 0.018872913562169524 0.04405075863545737 5.19112075782304e-06 5.284738868280427 0.44408289802871137 SMS(ph)LDMGQPSQANTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SMSLDMGQPSQANTK 15 0 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 S(0.066)MS(0.934)LDMGQPSQANTK;S(0.056)MS(0.944)LDMGQPSQANTK 116.0 9.038e-05 17037600.0 76911.0 96719.0 59878.0 61135.0 64228.0 42529.0 45283.0 41504.0 30645.0 36220.0 True False 89930.51323850757 106320.62312639716 61305.718608579555 57709.80415234421 51642.98446455583 40298.704371974345 40993.466419470664 40414.563977123 31093.125150355885 42786.39928263774 2.101848128056908 2.4849163497976545 1.4328319194052104 1.3487885197145397 1.2069953380141525 0.9418578110714524 0.9580957291749803 0.9445656716788222 0.7267058147370942 1.0 15.384864652676328 -5.532738431948588 0.984168353590301 0.9202527580545218 2.473796396102225 0.8851341757863164 0.1813666350089512 0.23064896604354174 0.3675636233422449 0.06601946836425186 0.29619512061823555 2.9326590032250727e-06 5.532738431948588 1.553543638047703 up SMS(ph)LDMGQPSQANTK ddPTM_PC-9_Lapatinib_30min_R1 2 SMSLDMGQPSQANTK 15 0 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 S(0.207)MS(0.793)LDMGQPSQANTK;S(0.003)MS(0.997)LDMGQPSQANTK 114.06 0.002508 5763700.0 53114.0 61455.0 55023.0 47389.0 48466.0 43857.0 41145.0 41804.0 45565.0 46057.0 True False 52356.584620085334 61312.704723283954 50499.22133492223 50874.14514506974 45615.325167822186 41981.338345660384 43275.28677596883 43746.36645300504 40432.989879278604 54017.891082905095 0.9692452550531816 1.1350443990710966 0.9348610307169801 0.9418017646595935 0.8444484642655358 0.7771747009010153 0.8011287724941201 0.8098495808706115 0.7485110778801642 1.0 15.721149696115592 -5.90329232715664 1.4061461182779478 0.8135331949001917 1.0474744389308515 0.5366689129372977 0.0781700285663058 0.2826581622286397 1.1346031113136923 0.02546542278314181 0.05087776912511454 1.2494177538376817e-06 5.90329232715664 0.23394124403065975 SMS(ph)PTSTPK ddPTM_PC-9_Lapatinib_30min_R1 2 SMSPTSTPK 9 0 E9PQ01;O94913;E9PKN0 E9PQ01 PCF11 Pre-mRNA cleavage complex 2 protein Pcf11 1 SMS(0.831)PT(0.051)S(0.105)T(0.013)PK;S(0.017)MS(0.961)PT(0.018)S(0.005)TPK 111.06 0.0022604 20931900.0 210797.0 181778.0 200250.0 171499.0 170961.0 175087.0 161350.0 164857.0 185923.0 140149.0 True False 207790.99612456473 181357.10420940688 183786.21798735368 184111.60856389292 160905.41010225806 167598.9371577317 169703.91350838655 172516.85806006737 164982.3938840145 164373.56791319602 1.2641387466523633 1.1033227939979966 1.118100801245668 1.1200803809352142 0.9789007572508892 1.0196221891724038 1.032428240518606 1.049541360270112 1.003703916502804 1.0 17.326618799573126 -1.5228787452810075 0.45910271573831957 1.0135465851517806 6.698275607461365 0.8127451561592735 0.035041481700271035 39.4317952051389 0.46519420606408524 0.022050915943646866 211.32701811783753 0.02999999999995372 1.5228787452810075 5.684729022309584 SMS(ph)YSSQK ddPTM_PC-9_AZD4547_30min_R2 1 SMSYSSQK 8 0 Q9C0B5;Q9C0B5-2 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5 1 S(0.001)MS(0.985)Y(0.001)S(0.011)S(0.002)QK 71.221 0.031702 17710000.0 37218.0 64965.0 68039.0 63353.0 72991.0 42294.0 92953.0 113360.0 85958.0 58261.0 True False 49052.54981750887 85963.66579018356 67136.75840410707 48747.94464409284 62857.459566370904 39649.349494038564 101225.63692617865 95842.8167536535 90501.56439326506 56221.30012326825 0.8724904922148455 1.5290230855868425 1.194151651721075 0.8670725247763805 1.1180363924091494 0.7052371504590825 1.800485522466324 1.704742091405089 1.6097380209072978 1.0 15.77882919612263 -7.272050261216525 24.99928339871844 1.5874699193823454 1.071196246051442 0.38866071825497894 0.29098785845196334 715.4042202623526 1685488.9984868832 0.11944255436655196 0.08146626055604407 5.3450249745426814e-08 7.272050261216525 -0.5162736733309035 SMS(ph)YSSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SMSYSSQK 8 0 Q9C0B5;Q9C0B5-2 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5 1 S(0.001)MS(0.994)Y(0.002)S(0.002)S(0.001)QK 71.221 0.031702 13284000.0 174430.0 128400.0 115760.0 91329.0 244720.0 93099.0 97890.0 148170.0 107520.0 98948.0 True False 203957.55385046144 141146.70343396207 118520.157422245 86212.13222261291 196768.8727372192 88216.72454857724 88617.15053777312 144280.69449909194 109092.27659214445 116886.48912806321 1.744919839512002 1.2075536230651849 1.0139765366071685 0.737571406804401 1.6834184532793626 0.754721313016128 0.7581470809742807 1.2343658841614713 0.9333181055050831 1.0 16.834748653284663 -4.768817141343118 2.47301780240926 1.0196793811289018 1.9216950280762108 0.4045394746515443 0.26709685183236054 0.5712210189503677 4.267134835334205 0.0689309384236123 1.124947485541191 1.7028753490808935e-05 4.768817141343118 0.9020156469473091 SMS(ph)YSSQK ddPTM_PC-9_Lapatinib_30min_R1 1 SMSYSSQK 8 0 Q9C0B5;Q9C0B5-2 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5 1 S(0.003)MS(0.996)YS(0.001)SQK 88.056 0.0099169 10623000.0 86891.0 79233.0 34862.0 19301.0 35751.0 18173.0 22504.0 12632.0 47396.0 12180.0 True False 85651.91840614229 79049.54085656107 31995.78093121164 20720.45992624854 33648.19646917035 17395.783153332108 23669.147007082327 13218.928835383214 42057.763377993804 14285.296771170157 5.9958095220675105 5.533629585917651 2.239770124746996 1.4504745864338986 2.3554425930497565 1.2177404104365106 1.6568887147553117 0.9253520628329521 2.944129481641053 1.0 13.802243387531687 -5.274191611099014 3.2834364706961625 1.663199881347193 5.953228832984378 0.8874947971299709 0.5798494127321053 0.06617518664888236 1.4813923587706035 0.14641801956390785 0.4043805296238745 5.318735444270658e-06 5.274191611099014 4.290028951637185 SMSSIPPY(ph)PASSLASSSPPGSGR ddPTM_PC-9_Lapatinib_30min_R1 1 SMSSIPPYPASSLASSSPPGSGR 23 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 SMSSIPPY(0.336)PAS(0.233)S(0.066)LAS(0.066)S(0.066)S(0.233)PPGSGR 125.59 5.2413999999999995e-08 4445200.0 49531.0 42073.0 40391.0 38908.0 56402.0 43802.0 35816.0 44213.0 49243.0 36896.0 True False 48824.67885712704 41975.582553457425 37070.20789376884 41769.42411328313 53084.54525059844 41928.69056744912 37670.37723096607 46267.29738749192 43696.73478822156 43273.42443917029 1.1282832244016228 0.9700083387775967 0.85665066664365 0.9652442498975013 1.2267239290299223 0.9689247179036762 0.8705199026695829 1.0691850249228632 1.0097822244145787 1.0 15.401193672389764 -4.755498094015076 24.77790882080989 0.9927614241776261 1.128283471819532 0.14613436255697887 0.09809859564742866 378.86028166942305 1579846.0243926977 0.025724911746827558 0.22583305376023977 1.7559086003250927e-05 4.755498094015076 0.1355220476419059 SMSSIPPYPAS(ph)SLASSSPPGSGR ddPTM_PC-9_AZD4547_30min_R2 3 SMSSIPPYPASSLASSSPPGSGR 23 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 SMSSIPPYPAS(0.289)S(0.289)LAS(0.084)S(0.084)S(0.253)PPGSGR;SMSSIPPY(0.12)PAS(0.415)S(0.415)LAS(0.01)S(0.01)S(0.029)PPGSGR;SMSSIPPY(0.021)PAS(0.238)S(0.238)LAS(0.132)S(0.238)S(0.132)PPGSGR 147.84 1.2670999999999998e-08 24648000.0 175955.0 171327.0 243076.0 328334.0 284357.0 237762.0 205473.0 269014.0 203385.0 241829.0 True False 231905.0299086404 226705.10226791035 239852.65341696332 252641.66900973232 244878.9389091063 222894.7045538746 223759.69894605575 227444.06762674107 214135.5158812934 233362.64031701902 0.9937538827706163 0.9714712773215776 1.0278108487765125 1.0826140322483628 1.0493493670471101 0.9551430522515347 0.9588497055144823 0.9746378739877228 0.9176083866311852 1.0 17.832214088851707 -6.772105394225378 24.982481932970487 0.9595127748992139 1.0253830212202848 0.47074354184374034 0.03377283847237993 206.5252874478747 483731.8458179896 0.012976620348200919 0.01156261095350157 1.690030746610941e-07 6.772105394225378 0.06587024632107086 SMSSIPPYPAS(ph)SLASSSPPGSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SMSSIPPYPASSLASSSPPGSGR 23 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 SMSSIPPY(0.133)PAS(0.431)S(0.431)LAS(0.001)S(0.002)S(0.003)PPGSGR 140.56 1.4240000000000002e-08 15477000.0 60656.0 63990.0 64477.0 75170.0 83531.0 65343.0 72669.0 65547.0 63605.0 63970.0 True False 70923.86278939171 70342.5043048227 66014.37621038417 70958.46860442821 67163.70018230061 61916.29805022273 65785.26624200054 63826.46070278723 64535.10279616205 75567.2546137587 0.9385528580057537 0.9308595987026274 0.8735844189099968 0.9390108052371753 0.8887937047017183 0.8193535462772983 0.8705525505490954 0.8446311967930908 0.8540088312856611 1.0 16.20547358965171 -6.518878672514504 24.88542391875279 0.8660538536958287 0.9173919774350905 0.1254339914245456 0.04874666704340109 253.89916112264928 1579580.8748321293 0.014900166352669072 0.015240259600645841 3.027759165529619e-07 6.518878672514504 0.05133812373926183 SMSSIPPYPAS(ph)SLASSSPPGSGR ddPTM_PC-9_Lapatinib_30min_R1 1 SMSSIPPYPASSLASSSPPGSGR 23 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 SMSSIPPY(0.001)PAS(0.437)S(0.437)LAS(0.045)S(0.045)S(0.034)PPGSGR 138.28 1.0684e-08 8573800.0 70585.0 54957.0 63346.0 53628.0 60463.0 59322.0 55186.0 57128.0 67810.0 51438.0 True False 69578.44495629631 54829.75044304802 58137.93640263131 57571.98201776367 56906.68521483165 56784.93634633615 58043.26105282817 59782.37543601744 60172.52372904388 60328.98976317329 1.1533169249051338 0.9088458245080347 0.9636815837768352 0.9543004489842696 0.9432726362271903 0.9412545538927533 0.9621122661042735 0.990939441729397 0.9974064536014339 1.0 15.880563803520651 -10.846513528947185 14.644167286581704 0.9999999999780439 0.9738175618270603 0.0023331087281746044 0.06317036824379116 0.0 0.0 0.0581549767402554 0.01410465373775911 1.42392288854727e-11 10.846513528947185 -0.026182438150983645 SMSSIPPYPASSLASSS(ph)PPGSGR ddPTM_PC-9_AZD4547_30min_R2 4 SMSSIPPYPASSLASSSPPGSGR 23 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 SMSSIPPYPAS(0.021)S(0.021)LAS(0.18)S(0.18)S(0.595)PPGS(0.002)GR;SMSSIPPYPAS(0.006)S(0.006)LAS(0.18)S(0.18)S(0.629)PPGSGR;SMSSIPPY(0.002)PAS(0.002)S(0.002)LAS(0.289)S(0.289)S(0.416)PPGSGR;SMSSIPPYPAS(0.015)S(0.015)LAS(0.128)S(0.128)S(0.714)PPGSGR 193.47 1.8247000000000003e-24 57771000.0 265290.0 247033.0 373794.0 481072.0 412308.0 352921.0 307379.0 406129.0 310875.0 344134.0 True False 349646.70162520604 326881.58625639084 368837.2473273392 370168.2828883086 355066.1511541326 330852.7940791978 334735.13552797446 343371.09496599034 327307.2178361093 332085.9734062367 1.0528800660830306 0.9843281933998478 1.11066795006167 1.1146760553945056 1.0691994832307614 0.9962865660527904 1.0079773382012045 1.0339825300177574 0.9856098843287139 1.0 18.341197262243945 -6.7564407754283105 24.99683352727076 1.0070955485291357 1.0669404228946195 0.42916964632322363 0.03545542009875393 140.5175869860234 702695.7331511113 0.012973058925478667 0.01258590652282432 1.7521013513059933e-07 6.7564407754283105 0.0598448743654838 SMSSIPPYPASSLASSS(ph)PPGSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SMSSIPPYPASSLASSSPPGSGR 23 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 SMSSIPPY(0.051)PAS(0.164)S(0.19)LAS(0.121)S(0.121)S(0.353)PPGS(0.002)GR;SMSSIPPY(0.001)PAS(0.101)S(0.101)LAS(0.154)S(0.154)S(0.489)PPGSGR;SMSSIPPYPAS(0.002)S(0.002)LAS(0.257)S(0.176)S(0.563)PPGSGR;SMSSIPPYPASSLAS(0.334)S(0.159)S(0.506)PPGSGR 173.19 8.7713e-24 50861000.0 219003.0 216043.0 241134.0 242252.0 286176.0 247197.0 249507.0 224103.0 225857.0 198700.0 True False 256075.88239358264 237490.32126155336 246883.54906578807 228679.4058315805 230101.86713160446 234233.55415455223 225871.89068575128 218220.5337067554 229159.73134553494 234722.7370916652 1.0909717804354782 1.011790865274408 1.0518092628128044 0.9742533197466735 0.9803134966074625 0.9979159115849866 0.9622923347112408 0.9296949090259403 0.9762996724771585 1.0 17.84059807386319 -4.252330771930928 0.5062218977198856 0.9640594414063534 1.2331574226837703 0.6595320649055483 0.025447034190887875 4.323947333486212 0.5710156769038098 0.014927738126492767 0.773078713939804 5.593314353346787e-05 4.252330771930928 0.2690979812774169 SMSSIPPYPASSLASSS(ph)PPGSGR ddPTM_PC-9_Lapatinib_30min_R1 6 SMSSIPPYPASSLASSSPPGSGR 23 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 SMSSIPPY(0.025)PAS(0.045)S(0.045)LAS(0.169)S(0.169)S(0.529)PPGS(0.017)GR;SMSSIPPY(0.001)PAS(0.048)S(0.048)LAS(0.072)S(0.21)S(0.621)PPGSGR;SMSSIPPY(0.014)PAS(0.19)S(0.19)LAS(0.121)S(0.15)S(0.327)PPGS(0.009)GR;SMSSIPPY(0.001)PAS(0.129)S(0.129)LAS(0.058)S(0.172)S(0.511)PPGSGR;SMSSIPPYPAS(0.069)S(0.069)LAS(0.165)S(0.165)S(0.528)PPGS(0.004)GR;SMSSIPPYPAS(0.102)S(0.102)LAS(0.152)S(0.152)S(0.49)PPGSGR 171.3 2.7101999999999996e-10 59457900.0 535600.0 406183.2 470272.0 396799.2 474538.0 473935.0 429266.0 411766.0 525096.0 380474.2 True False 527962.2457829885 405242.7077562221 431608.05146241596 425981.1368513283 446626.6078176039 453665.9048464447 451491.2930653312 430898.1515856875 465954.15897398576 446238.65851999616 1.1831387435907914 0.9081299883346234 0.967213492649641 0.9546038397124661 1.000869376263577 1.016644112258409 1.0117709087840037 0.9656226401693047 1.0441815160510262 1.0 18.767455976900933 -6.512823118313849 23.459608058685998 1.006086925644564 0.9918796883566986 0.0 0.06990087074453304 1818.1778443665762 4241778.560818772 0.021818510827113412 0.023138693839563934 3.0702722100032494e-07 6.512823118313849 -0.014207237287865326 SMYEEEINETR ddPTM_PC-9_Lapatinib_30min_R1 1 SMYEEEINETR 11 0 P20700;E9PBF6;A0A0D9SFE5 P20700 LMNB1 Lamin-B1 0 96.171 0.027252999999999996 1554000.0 6679.0 5495.3 7122.7 5539.6 8747.2 4868.4 4970.0 5856.1 7036.8 5240.8 False True 6583.756235221409 5482.575970480225 6537.099100417104 5947.000663563875 8232.706893656876 4660.189880794694 5227.322281603234 6128.195784744115 6244.241483210964 6146.665297072956 1.0711102552397957 0.8919594130318158 1.0635196133959128 0.9675165925165697 1.339377775714792 0.7581655508416698 0.850432230967983 0.9969951979754559 1.0158746542103854 1.0 12.585588213135738 SNATNSSYS(ph)PTTGR ddPTM_PC-9_AZD4547_30min_R2 1 SNATNSSYSPTTGR 14 0 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 SNAT(0.005)NS(0.015)S(0.052)YS(0.593)PT(0.319)T(0.016)GR 106.35 0.00088389 9922600.0 14559.0 15326.0 20926.0 33553.0 26663.0 21056.0 17790.0 25363.0 17945.0 22958.0 True False 19188.45915398764 20279.829783735157 20648.50756719449 25817.87423868243 22961.302686881256 19739.364991404826 19373.27553620343 21443.731133758974 18893.536064556407 22154.247407871346 0.8661300382142536 0.9153924035591381 0.932033807650723 1.1653690492555124 1.036428918759983 0.8909968652056978 0.8744722932596734 0.9679286657302596 0.852817778763434 1.0 14.435295698051323 -6.775428744221251 24.958712627434245 0.9125654787797897 0.9866032232267016 0.12713386309280195 0.0855560540548371 502.70412238816095 896879.1065477177 0.03253369611987343 0.02883026711632626 1.677147486946489e-07 6.775428744221251 0.07403774444691191 SNATNSSYS(ph)PTTGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SNATNSSYSPTTGR 14 0 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 S(0.028)NATNS(0.004)S(0.012)YS(0.892)PT(0.059)T(0.006)GR;SNATNS(0.002)S(0.006)YS(0.477)PT(0.477)T(0.038)GR;SNATNS(0.002)S(0.002)YS(0.804)PT(0.065)T(0.127)GR 157.37 2.5642e-05 25949000.0 46336.4 52606.1 58251.0 53724.0 66195.0 51929.0 58418.0 54846.0 52779.6 45130.3 True False 54180.23733438356 57828.48594639692 59639.92475814767 50714.01845555802 53224.56493478341 49205.75182422012 52884.224130305774 53406.350614140494 53551.40180080678 53312.06613874174 1.0162847036050422 1.084716652997493 1.1186946797923385 0.9512671732432496 0.9983586979403384 0.9229758924774147 0.9919747621988139 1.0017685391362132 1.0044893338300223 1.0 15.70217447516851 -5.767128088246744 24.999968529370985 0.980315874751789 1.0743804794513785 0.6059309603021072 0.033868761777527526 88.31690946908314 388125.170582015 0.009631806874446749 0.01474601031200872 1.7095110476501364e-06 5.767128088246744 0.09406460469958944 SNATNSSYS(ph)PTTGR ddPTM_PC-9_Lapatinib_30min_R1 2 SNATNSSYSPTTGR 14 0 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 SNATNS(0.001)S(0.075)YS(0.802)PT(0.111)T(0.011)GR;SNATNS(0.001)S(0.002)YS(0.81)PT(0.178)T(0.009)GR 144.15 2.474e-05 20543700.0 45620.0 46964.0 49806.0 39545.0 45841.0 43233.0 38239.0 38802.0 54394.0 32295.0 True False 44969.45043431661 46855.257743459566 45711.142936719836 42453.271218252834 43144.72250687359 41384.0253710453 40218.82831513601 40604.88257366526 48267.5749257869 37877.14771961746 1.1872448994100442 1.2370323681788777 1.2068264293576934 1.1208148916732 1.1390699961425008 1.092585578971976 1.0618230446720183 1.0720153184247039 1.2743191563177816 1.0 15.209040074513746 -5.778253221308006 3.617486152357409 1.108877406921382 1.2153301276644752 0.32571308749658145 0.06726341593996954 0.2640933153846605 7.3293320863510925 0.018825073866543415 0.031501636868596514 1.666275384720399e-06 5.778253221308006 0.1064527207430932 SNATNSSYSPT(ph)TGR ddPTM_PC-9_AZD4547_30min_R2 1 SNATNSSYSPTTGR 14 0 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 SNATNS(0.007)S(0.007)YS(0.195)PT(0.764)T(0.027)GR 121.32 0.0001807 7871200.0 5477.8 6957.7 9233.6 13036.0 10433.0 7966.1 8065.7 9716.4 8144.4 10290.0 True False 7219.626454681884 9206.640459760805 9111.15643087294 10030.751604192299 8984.558036688748 7467.978507695192 8783.531674668697 8214.953640659844 8574.896356877858 9929.750232032238 0.7270702974373107 0.9271774460208714 0.9175614912731028 1.0101715924167198 0.9048120875896346 0.7520812037753324 0.8845672317450674 0.8273071777937921 0.8635560972335662 1.0 13.277541714043096 -6.5811156070726 24.99992631053084 0.8528501437671739 0.9066067785736425 0.016738770746858034 0.08779673742860727 217.82960003686156 93507.98897254185 0.028562105629426036 0.02856209942563123 2.623520082176704e-07 6.5811156070726 0.05375663480646853 SNATNSSYSPT(ph)TGR ddPTM_PC-9_Lapatinib_30min_R1 2 SNATNSSYSPTTGR 14 0 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 S(0.279)NAT(0.016)NS(0.027)S(0.014)YS(0.111)PT(0.443)T(0.111)GR;SNAT(0.001)NS(0.098)S(0.056)YS(0.209)PT(0.607)T(0.029)GR 130.21 4.9297e-05 11706900.0 23682.0 20473.0 22648.1 19724.0 20487.4 20689.8 18121.6 16423.8 18213.4 13664.400000000001 True False 23344.290337253093 20425.596026357383 20786.060642194192 21174.568757335168 19282.371411778153 19804.945484279462 19059.847778330215 17186.909706029666 16162.015096395315 16026.273333331483 1.4566262443996623 1.2745069051004003 1.2969990096801414 1.321240959574566 1.2031725037207888 1.235779839289842 1.189287576837311 1.0724208522192298 1.0084699518247648 1.0 13.968151367201708 -7.2441683788756155 0.47189383891334774 0.9708733307822301 1.3764972460229026 0.8691185939152701 0.049806814127770944 0.3521074811427851 0.17321815858601305 0.050146798417963094 0.04906066764903968 5.699432586255788e-08 7.2441683788756155 0.40562391524067243 SNATNSSYSPTT(ph)GR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNATNSSYSPTTGR 14 0 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 SNATNS(0.014)S(0.026)YS(0.127)PT(0.067)T(0.766)GR 109.1 0.0015210999999999998 8406700.0 18811.0 24281.0 26974.0 25394.0 29734.0 26733.0 23636.0 22424.0 25401.0 21272.0 True False 21995.330765814568 26691.45721246134 27617.162459464653 23971.2565084588 23907.83614730497 25331.07441924313 21397.02697017884 21835.393760191946 25772.441571029198 25128.445210940656 0.875316024575927 1.062200903732801 1.0990398422040228 0.9539490528455764 0.9514252054438989 1.0080637383889652 0.8515062030524198 0.8689512453673437 1.025628181715284 1.0 14.617033788696466 -5.9684488983547785 24.737955460243676 0.9432099284775254 1.018738416079635 0.11318808020309068 0.07557949633049264 318.71407745466377 249888.74854352506 0.02162521315487701 0.03207502733279323 1.0753531253275534e-06 5.9684488983547785 0.0755284876021095 SNDRNS(ph)MDIQCEVDALLER ddPTM_PC-9_AZD4547_30min_R2 2 SNDRNSMDIQCEVDALLER 19 1 Q02241;H7BYN4;A0A2U3TZL8;A0A2R8Y531;H0YME6;Q02241-2 Q02241;Q02241-2 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 S(0.005)NDRNS(0.995)MDIQCEVDALLER;S(0.043)NDRNS(0.957)MDIQCEVDALLER 88.637 0.0016819000000000003 11682500.0 19593.7 19692.4 24116.8 33900.0 25749.1 25444.9 19799.6 28923.1 22429.8 22123.6 True False 25824.08902572208 26057.58319412932 23796.995474362808 26084.878749778996 22174.281926818945 23853.826380594463 21561.726043092396 24453.699481718413 23615.393436655733 21349.059497899747 1.2096124903423766 1.2205494671412942 1.1146624738529527 1.2218280038212055 1.0386538071618743 1.117324460262108 1.0099614011199682 1.1454227987946772 1.1061561488916616 1.0 14.381884894940754 -6.260195146976218 24.99941838231148 1.076263224452584 1.188226376672805 0.5673757036807846 0.05199231482424119 90.0242897452214 1808788.6245250562 0.01529331799070915 0.01864547973092436 5.492939972476436e-07 6.260195146976218 0.11196315222022091 SNDRNS(ph)MDIQCEVDALLER ddPTM_PC-9_Lapatinib_30min_R1 2 SNDRNSMDIQCEVDALLER 19 1 Q02241;H7BYN4;A0A2U3TZL8;A0A2R8Y531;H0YME6;Q02241-2 Q02241;Q02241-2 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 S(0.024)NDRNS(0.976)MDIQCEVDALLER;S(0.24)NDRNS(0.76)MDIQCEVDALLER 86.016 0.00059468 4315100.0 9018.2 10596.2 10557.3 8122.9 8927.6 9419.400000000001 7829.700000000001 8476.9 8806.6 7169.2 True False 8889.598814264664 10571.665149928584 9689.319546356503 8720.285163200055 8402.49612033692 9016.55421969385 8235.083554983667 8870.767720444892 7814.70797039076 8408.386667641475 1.0572300211258205 1.257276284713712 1.1523399112512895 1.0370937384170116 0.99929944381278 1.0723286851677296 0.9793892550963741 1.0549904602487927 0.9293944580908243 1.0 13.03761329918841 -5.785159340554346 3.897873959337491 1.0114346237325136 1.1685401199496186 0.5679243407658632 0.0582860437127401 0.14183962718956805 4.66297426166897 0.015675730247698784 0.025785285447929136 1.6399879591190477e-06 5.785159340554346 0.157105496217105 SNDS(ph)GEEAEKEFIFV ddPTM_PC-9_AZD4547_30min_R2 1 SNDSGEEAEKEFIFV 15 1 Q5VZK9-2;Q5VZK9 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(0.003)NDS(0.997)GEEAEKEFIFV 85.473 0.027898000000000003 21876000.0 15646.0 15311.0 16590.0 22047.0 20067.0 20069.0 16941.0 18002.0 17842.0 15418.0 True False 20621.10254298309 20259.981327076144 16370.005760286565 16964.40477275449 17281.043431633563 18814.08225743273 18448.716180934378 15220.204544806567 18785.091694835068 14878.220512873966 1.385992533525086 1.361720731961554 1.10026637568127 1.1402173235754485 1.1614993484389118 1.264538473613367 1.2399813650409939 1.022985546667808 1.2625899500938655 1.0 13.860914364948862 -5.248747774980492 22.668904044908214 1.157337762805936 1.3738568297626144 0.5136414217940772 0.08721685878326335 175.79489571652226 313986.81784848234 0.02155932339343548 0.05598738447711708 5.639650944989689e-06 5.248747774980492 0.21651906695667833 SNEDQS(ph)MGNWQIK ddPTM_PC-9_AZD4547_30min_R2 1 SNEDQSMGNWQIK 13 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 S(0.002)NEDQS(0.998)MGNWQIK 70.977 0.023743 5071400.0 39268.0 40564.0 56947.0 52317.0 51053.0 54010.0 52676.0 54623.0 47874.0 42366.0 True False 51754.40717485998 53675.51972774587 56191.84557149121 40256.12393959254 43965.17218892651 50632.746161938376 57364.06195306645 46182.27046166922 50404.52190329193 40882.77923520679 1.2659219393355463 1.3129126916479892 1.3744624661696385 0.9846719008018271 1.0753958759991853 1.2384859128739285 1.4031350858766118 1.1296264912904623 1.2329035072029875 1.0 15.319205654410114 -13.245160613761339 0.37347331209950296 5.2454670115995135e-18 1.2287779064107012 0.22808235301215662 0.12368263901343152 329.04254519740465 6.413456127633133 258.3282815529007 0.09289932671072026 5.686425926515948e-14 13.245160613761339 1.2287779064107012 SNEDQS(ph)MGNWQIK ddPTM_PC-9_Lapatinib_30min_R1 1 SNEDQSMGNWQIK 13 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 SNEDQS(1)MGNWQIK 74.296 0.017294999999999998 4474500.0 11155.0 29218.0 29752.0 28127.0 34901.0 32177.0 29545.0 35273.0 29609.0 26895.0 True False 10995.927654423534 29150.34751614858 27305.905406041216 30195.55340892142 32848.19179800605 30800.864718250537 31074.695535204733 36911.912350417355 26274.122623407457 31543.764914665146 0.348592746749497 0.9241239146629631 0.8656514363428544 0.9572590174511184 1.041352923053724 0.9764485882257757 0.9851295690058122 1.1701809359242492 0.8329418728070802 1.0 14.945067243214886 -4.635101018268833 2.260480553531159 0.986887984162546 4.546437172738571e-15 0.8175984014111702 0.08842031953582666 0.4374577234794287 1.8078569409550984 0.02279365333830459 1.003582990083386 2.3168556793356446e-05 4.635101018268833 -0.9868879841625414 down SNEDS(ph)LILEK ddPTM_PC-9_AZD4547_30min_R2 1 SNEDSLILEK 10 0 A0A0U1RRH6;O94880 A0A0U1RRH6 PHF14 PHD finger protein 14 1 SNEDS(1)LILEK 138.77 0.00011982 6250500.0 28642.0 32128.0 31127.0 37823.0 36384.0 38587.0 32789.0 39824.0 36599.0 28900.0 True False 37749.56020939036 42512.74770271715 30714.23564197949 29103.4917095248 31332.709633555394 36174.14879005216 35707.15747929029 33670.11586448041 38533.54842166062 27888.219796475383 1.3536023627496399 1.5243980437966165 1.1013336765891837 1.0435765323824293 1.1235105669066527 1.2971121517990898 1.28036704170709 1.2073239565020841 1.3817141683073881 1.0 14.767368224537169 -14.52287874434646 0.0265211533263491 6.1265242729791905e-09 2.008585026331795 0.1712032326230699 0.14338225413770486 4343.840303168512 8.659758246350686 486.82196392563236 218.3824220777759 3.0000000064509947e-15 14.52287874434646 2.008585020205271 SNEDS(ph)LILEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNEDSLILEK 10 0 A0A0U1RRH6;O94880 A0A0U1RRH6 PHF14 PHD finger protein 14 1 SNEDS(1)LILEK 118.52 0.00086621 949630.0 5355.2 5548.3 8426.9 7391.6 5634.6 5080.7 6640.6 4995.1 5526.3 5753.2 True False 6261.7295899787405 6099.098556562716 8627.829255196211 6977.472615890528 4530.540578314542 4814.259147938823 6011.554294219391 4863.983917745932 5607.111682767556 6796.209617693856 0.9213561591267576 0.8974264920675462 1.2695060541884633 1.0266711900299184 0.6666275517046045 0.708374140698214 0.8845451556656487 0.7156906851552377 0.825035129606583 1.0 12.730514635380752 -6.238122338368885 21.09512988473285 0.7854714791513291 1.0365583944471104 0.42273660090257204 0.13012771492416236 101.5803060160766 91899.2871269953 0.03878197745844641 0.049996396666010016 5.779332238604193e-07 6.238122338368885 0.2510869152957813 SNEDS(ph)LILEK ddPTM_PC-9_Lapatinib_30min_R1 2 SNEDSLILEK 10 0 A0A0U1RRH6;O94880 A0A0U1RRH6 PHF14 PHD finger protein 14 1 SNEDS(1)LILEK;SNEDS(1)LILEK 128.95 0.00026255 11190900.0 62079.0 62914.0 64495.0 54642.0 63526.0 56938.0 55625.0 53066.0 60864.0 41267.0 True False 61193.742076105635 62768.32649842462 59192.470057899525 58660.55496036849 59789.52557692137 54502.8944689607 58504.99032478469 55531.64008695737 54008.855393666476 48399.94596517893 1.2643349255003535 1.29686769781898 1.2229862839203418 1.2119962902969252 1.2353221555234093 1.126094118125101 1.208782141345277 1.147349216606756 1.1158866878182643 1.0 15.562717816392048 -11.559580626248392 0.03554234883252501 9.101157324841656e-07 2.001289223809916 0.8748332868588016 0.029158246969006825 173.91051162042436 0.8487294955911326 31.754786771166575 17.616281550140982 2.7568895915967252e-12 11.559580626248392 2.0012883136941833 SNEEGS(ph)EEKGPEVR ddPTM_PC-9_AZD4547_30min_R2 1 SNEEGSEEKGPEVR 14 1 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 1 S(0.001)NEEGS(0.999)EEKGPEVR 67.994 0.015588 5068100.0 12553.0 13526.0 12797.0 17910.0 17863.0 15223.0 15066.0 12634.0 14097.0 13363.0 True False 16544.592881379696 17898.014984653644 12627.303418588743 13781.126206741641 15383.030787824311 14271.103403502826 16406.84481329066 10681.705600438072 14842.138640404115 12895.16543738064 1.2830074155869344 1.3879631922185887 0.9792277175432418 1.068704878092744 1.1929300839547061 1.1067018467350254 1.272325267400628 0.8283496363275676 1.1509847401708837 1.0 13.654542661723307 -5.2545940319242925 24.863863717044946 1.0809530069982516 1.3354853260126385 0.43436493876295 0.11878444286905174 458.35661022169774 1664843.177282489 0.02993138085375321 0.07554151178124953 5.5642414620227715e-06 5.2545940319242925 0.2545323190143869 SNEEGSEEKGPEVR ddPTM_PC-9_AZD4547_30min_R2 4 SNEEGSEEKGPEVR 14 1 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 ;;; 146.84 0.00011499 51826300.0 79914.5 84948.0 104287.0 138733.0 128658.0 101735.0 97930.0 111458.0 91895.0 97133.0 False True 105325.64867513854 112405.77975132015 102904.0862400847 106750.25025348354 110796.05749873488 95373.49436742841 106645.58028445221 94234.72715004168 96752.38209263932 93732.40323498403 1.123684500130554 1.1992200762155067 1.097849651652562 1.1388831030595066 1.1820464820577878 1.0175082583589607 1.137766413788573 1.0053591276625902 1.0322191553126436 1.0 16.516260252461805 -7.4249829023061285 0.6932153667520722 0.9986375291740898 1.1520186117321725 0.5590462664076548 0.04695848924775666 0.5108274475239 0.477590161782454 0.03979192828985117 0.023600190327144853 3.75852200883024e-08 7.4249829023061285 0.1533810825580827 SNEEGSEEKGPEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNEEGSEEKGPEVR 14 1 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 ; 184.02 8.9277e-06 30466600.0 63405.0 57941.0 61087.0 77200.0 83850.0 59941.0 79339.0 72779.0 69919.0 56203.0 False True 74138.21419416684 63692.99956127109 62543.54575373757 72874.73428577694 67420.19442226137 56797.588439900166 71823.4355553824 70868.62836572468 70941.4331012475 66392.15899729672 1.1166712351858525 0.9593452076752689 0.942032111898698 1.0976406760434492 1.0154842897187077 0.8554863902258817 1.081805993962432 1.0674246693590765 1.0685212557123804 1.0 16.01872524696983 SNEEGSEEKGPEVR ddPTM_PC-9_Lapatinib_30min_R1 3 SNEEGSEEKGPEVR 14 1 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 ;; 137.73 9.8182e-05 66892600.0 118262.0 105833.0 97386.0 100882.0 110994.0 104740.0 97544.0 102995.0 96613.0 83058.0 False True 116575.56219340533 105587.95019086039 89379.29900083129 108301.19881248657 104465.55114259993 100260.51436086521 102594.35103354251 107780.52370173311 85731.42656000762 97414.46463217147 1.1966966367221181 1.083904229105516 0.9175156824843183 1.1117568548102428 1.0723823360016682 1.0292158843087644 1.0531736885372192 1.1064119082181787 0.8800687545091175 1.0 16.571848387008238 -4.855906254438283 3.8880370184593374 1.030000842064555 1.200814289864831 0.35316265833480076 0.07161928764693297 0.2526988252502749 6.3797127003049265 0.01740179069986853 0.10365121317124523 1.3934575582374481e-05 4.855906254438283 0.17081344780027607 SNES(ph)VDIQDQEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNESVDIQDQEEK 13 0 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 S(0.001)NES(0.999)VDIQDQEEK 102.15 0.0018216999999999999 9865500.0 43038.0 40739.0 37246.0 43743.0 43060.0 34800.0 42181.0 53785.0 36681.0 35274.0 True False 50323.48336075312 44783.29868532857 38134.08589624158 41292.22152671942 34622.7021087964 32975.02673810123 38185.310316005816 52373.20073991811 37217.39023136578 41668.896971169626 1.2076989557840114 1.0747416404210022 0.9151690749727848 0.990960273205436 0.830900374750778 0.791358282435851 0.9163983952449215 1.2568895398444242 0.8931695565907635 1.0 15.346683290118213 -4.953141365951678 2.593445211503517 0.9489520917345098 1.2201215754699 0.3174076827524632 0.1200162339766059 0.45356712175952946 5.162819819760255 0.033881973720325885 0.2302242956375159 1.1139318817988673e-05 4.953141365951678 0.2711694837353902 SNES(ph)VDIQDQEEK ddPTM_PC-9_Lapatinib_30min_R1 2 SNESVDIQDQEEK 13 0 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 S(0.023)NES(0.977)VDIQDQEEK;SNES(1)VDIQDQEEK 236.31 5.9403e-26 11220000.0 28983.0 37709.0 44490.0 55586.0 34340.0 39601.0 39089.0 46145.0 51682.0 84210.0 True False 28569.69710516874 37621.68712733405 40832.203936366386 59673.979869460214 32320.188715037613 37907.3575444398 41112.837156054105 48289.065160604645 45861.02892441297 98765.58629722832 0.28926773156785784 0.3809189874508935 0.41342541939137223 0.6041981028682949 0.32724139983103223 0.38381139590828917 0.41626682630453704 0.48892602141075725 0.4643421929010507 1.0 16.591720818859038 -14.522878745280305 0.28253073279221025 5.320708882961598 0.3853191391084502 0.8351036283815247 0.07846040580335152 91.87500763388283 0.8756559033465828 232.9195597790924 0.09162971801127798 3.000000000000222e-15 14.522878745280305 -4.935389743853148 SNETQNPHKPS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNETQNPHKPSPSR 14 1 Q96LW4;Q96LW4-2;A0A5S6SZ32 Q96LW4 PRIMPOL DNA-directed primase/polymerase protein 1 SNETQNPHKPS(0.954)PS(0.046)R 65.175 0.016661000000000002 3696200.0 7598.8 6856.2 7978.6 9088.5 10989.0 10389.0 9821.8 9639.7 9326.0 7752.3 True False 8885.126756858841 7536.838224952739 8168.840083008998 8579.300810314551 8835.78433519655 9844.182551210739 8891.408000325879 9386.668089106408 9462.375106941388 9157.73062282697 0.9702323777368353 0.8230028306539263 0.8920157645439997 0.9368369920086317 0.9648443155962764 1.074958737776441 0.9709182729357376 1.024999366732712 1.0332663731509035 1.0 13.160774413024997 -6.244074228644861 1.962670727808718 1.0188583800527011 0.8898021621164144 0.6157485768526967 0.04283587591217676 0.208139111280945 1.5755038052049055 0.014202786173413277 0.018779207906678853 5.700668294017487e-07 6.244074228644861 -0.12905621793628674 SNGDLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 SNGDLSPK 8 0 P49006 P49006 MARCKSL1 MARCKS-related protein 1 SNGDLS(1)PK;S(0.001)NGDLS(0.999)PK 97.163 0.0058975 64832000.0 681700.0 557240.0 452240.0 478460.0 552750.0 593840.0 583290.0 527160.0 545460.0 565150.0 True False 898466.4197591427 737356.9325778785 446243.00211163366 368158.4391333117 476010.20365951303 556707.0909240056 635201.6800175429 445699.5349316878 574291.9020213401 545364.2705182725 1.6474610977087092 1.3520448119513784 0.8182475938285403 0.6750688650421526 0.8728298302474955 1.0207986129985263 1.164729180761871 0.8172510724036414 1.0530427698821871 1.0 19.056860659775055 -5.05684009767553 3.372715246254643 0.9232940369998615 1.616634240012486 0.7538857492855713 0.1353125756129016 0.12132532660823106 2.649123464498367 0.03853495396060586 0.14965657915991365 8.773237823951595e-06 5.05684009767553 0.6933402030126246 SNGDLS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNGDLSPK 8 0 P49006 P49006 MARCKSL1 MARCKS-related protein 1 SNGDLS(1)PK;SNGDLS(1)PK 94.363 0.0067564999999999995 44948000.0 490820.0 478980.0 332850.0 491800.0 497990.0 422700.0 476270.0 357540.0 385940.0 366460.0 True False 573906.131863117 526529.9689314578 340786.40634065366 464246.04043711215 400412.4343511262 400532.86787917797 431154.25770380284 348154.9538449443 391583.6423732537 432896.2971042366 1.3257358302719018 1.2162958483441944 0.7872241195414894 1.0724185989637303 0.9249615601463815 0.9252397642540567 0.9959758505395246 0.804245626894592 0.9045668558328295 1.0 18.72366193455695 -5.110589395288655 4.962380143509368 0.9281760786966076 1.3016536149639568 0.7406423017288206 0.08241415084908357 0.09716200243830776 3.524764294499697 0.02052452857034754 0.05938308417742635 7.751943607278763e-06 5.110589395288655 0.37347753626734925 SNGDLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 SNGDLSPK 8 0 P49006 P49006 MARCKSL1 MARCKS-related protein 1 SNGDLS(1)PK 84.198 0.014156 39636000.0 380010.0 348480.0 217710.0 258340.0 307790.0 249100.0 249830.0 259040.0 259540.0 241980.0 True False 374590.98771470087 347673.1159705472 199810.72418490247 277339.18539697694 289686.3973384226 238446.57368046124 262764.97497242194 271075.94407201326 230307.87212263705 283805.92058191705 1.3198843313297963 1.2250382770651034 0.7040400135952399 0.9772142343905981 1.0207200637127238 0.8401747686995015 0.9258614987088619 0.9551454864514377 0.8114977716124198 1.0 18.114545160752385 -5.1105759208343216 5.993365487918568 0.9086860184212437 1.2971158451509297 0.7211112661559623 0.0922642334446731 0.10440059000235799 4.759429360769114 0.022841552554716784 0.06318077758317975 7.752184123414448e-06 5.1105759208343216 0.38842982672968596 SNGELS(ph)ESPGAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNGELSESPGAGK 13 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;F5GXF5;Q12830-2;A0A0A0MR81;F5H176 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 SNGELS(0.672)ES(0.328)PGAGK;SNGELS(0.799)ES(0.201)PGAGK 162.7 0.00013385 28559000.0 104388.0 104375.0 96589.0 122042.0 126681.0 108410.0 126363.0 113868.0 105065.0 91411.0 True False 122058.82664302028 114736.66020965589 98892.04807582239 115204.38240550269 101858.76743716776 102724.78875510214 114392.98185110485 110879.08565311893 106601.37686154823 107983.0906909223 1.130351297245109 1.0625428432870494 0.9158104981351107 1.0668742825230826 0.9432844233799155 0.9513043949550316 1.0593601379546493 1.0268189671518644 0.9872043500465372 1.0 16.720445889730343 -5.006829187445379 5.901051879191146 0.9957830140124346 1.1165669471088995 0.46764637834710854 0.0463739799791087 0.11850942315528752 17.20265779649502 0.011616957652441962 0.03912749980644796 9.84398203723886e-06 5.006829187445379 0.12078393309646485 SNGELSES(ph)PGAGK ddPTM_PC-9_AZD4547_30min_R2 4 SNGELSESPGAGK 13 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;F5GXF5;Q12830-2;A0A0A0MR81;F5H176 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 SNGELS(0.03)ES(0.97)PGAGK;SNGELS(0.074)ES(0.926)PGAGK;SNGELS(0.216)ES(0.784)PGAGK;SNGELS(0.005)ES(0.995)PGAGK 140.49 7.3007e-05 52337800.0 202123.0 184858.0 218919.0 296488.0 238646.0 251570.0 236915.0 264046.0 211920.0 224490.0 True False 266393.90958042705 244609.73340478382 216015.9910208667 228137.27229393745 205514.122229811 235839.28813106584 257999.97603483018 223243.7578734586 223121.6585567454 216630.673429438 1.2297146353431716 1.1291555786279697 0.9971625329006258 1.0531162031781591 0.948684315920534 1.088669874849854 1.1909669667295162 1.0305269994287058 1.029963370489275 1.0 17.72487800764838 -4.939420022210375 3.253023938977174 1.047647846159841 1.2304017628108783 0.4766709468164113 0.061536291410893625 0.25273314734960095 4.961753906480202 0.01684259328809794 0.09597359097911055 1.1496879454756464e-05 4.939420022210375 0.18275391665103724 SNGELSES(ph)PGAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNGELSESPGAGK 13 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;F5GXF5;Q12830-2;A0A0A0MR81;F5H176 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 SNGELS(0.034)ES(0.966)PGAGK 138.28 6.3377e-05 18017000.0 46793.0 45659.0 49810.0 65975.0 71352.0 59710.0 61291.0 60122.0 51925.0 41854.0 True False 54714.13069612254 50191.72377018135 50997.65930547692 62278.63464383591 57371.0878046177 56578.702486552436 55485.072771586994 58543.86120452463 52684.304892551125 49441.798883918294 1.106637135606309 1.0151678317373476 1.0314685237325516 1.2596352893642992 1.1603762221377938 1.1443495941438233 1.1222300568362686 1.1840965038908995 1.0655822822354368 1.0 15.593443614573594 -5.658706656352484 19.819651985279112 1.142791243509549 1.0474733638573728 0.2251793614060773 0.06873865265830176 3.4960559408088576 663.5729903745522 0.017787916910986124 0.03080955589474339 2.1942865629404743e-06 5.658706656352484 -0.09531787965217631 SNGELSES(ph)PGAGK ddPTM_PC-9_Lapatinib_30min_R1 2 SNGELSESPGAGK 13 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;F5GXF5;Q12830-2;A0A0A0MR81;F5H176 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 SNGELS(0.006)ES(0.994)PGAGK;SNGELS(0.005)ES(0.995)PGAGK 162.46 0.00010121 44272000.0 94084.0 92643.0 95652.0 90126.0 91886.0 90751.0 80633.0 78345.0 89500.0 75588.0 True False 92742.34490710754 92428.490825469 87787.86178739769 96754.16669152232 86481.44613482653 86869.79128091355 84807.78219970089 81985.1947124839 79419.56752321814 88653.28508532116 1.0461241771001606 1.0425839351188682 0.9902381136007473 1.0913771170284865 0.9755018784875888 0.9798823720667412 0.9566231202609209 0.9247846217269919 0.895844609105953 1.0 16.43588647134449 -6.765816758233464 1.4358604036134264 0.9372978078060589 1.038560951139964 0.5776992525741547 0.03608630732623742 0.2778237292349392 1.194620237165161 0.016164535926498524 0.014571517684963621 1.7146806296887482e-07 6.765816758233464 0.10126314333390518 SNLDEEVNVIPPHT(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 3 SNLDEEVNVIPPHTPVR 17 0 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 SNLDEEVNVIPPHT(1)PVR;SNLDEEVNVIPPHT(1)PVR;SNLDEEVNVIPPHT(1)PVR 195.48 9.7293e-12 14521900.0 62905.0 61426.4 72262.0 76541.0 78754.0 76322.0 66617.0 86788.0 65141.0 71098.0 True False 82907.48149471742 81281.28254127804 71303.75866484789 58895.65499666171 67820.36649299209 71549.57327479108 72545.78394577086 73376.90878983858 68584.2202720127 68608.88066054693 1.20840743496334 1.184704979278554 1.0392788510518673 0.85842611670138 0.9885071121994231 1.0428616905848338 1.0573818323126765 1.0694957866006036 0.9996405656483999 1.0 16.066107708946134 -5.283270332809207 4.133481068604169 1.0049750263907582 1.2012861855775367 0.657239884381875 0.05526098669486044 0.13133978532771529 5.345497625313834 0.01626313922957431 0.040212127186935856 5.208703869564003e-06 5.283270332809207 0.19631115918677855 SNLDEEVNVIPPHT(ph)PVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SNLDEEVNVIPPHTPVR 17 0 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 SNLDEEVNVIPPHT(1)PVR;SNLDEEVNVIPPHT(1)PVR;SNLDEEVNVIPPHT(1)PVR;SNLDEEVNVIPPHT(1)PVR;SNLDEEVNVIPPHT(1)PVR 182.82 6.7006e-07 31586600.0 191573.4 220089.0 216757.0 199720.0 235123.0 185189.2 204263.0 148077.6 180745.80000000002 151941.0 True False 224002.99287287702 241937.9814024715 221925.3089355001 188530.3359009763 189052.33599457823 175477.55234504543 184913.72990394518 144190.71990118647 183388.8653875414 179486.70053570566 1.2480200048488586 1.3479437790118731 1.236444306308656 1.050386102916141 1.0532943969125426 0.9776632576191199 1.0302363871642952 0.8033504402879271 1.0217406907597562 1.0 17.453517422763575 -5.867526486516539 1.2127828696972416 0.9592398778953503 1.3186221343805422 0.7896170995971821 0.06884289761362523 0.20575047158875429 0.6075767891998644 0.024803938015597316 0.05639867268170048 1.3566677880568233e-06 5.867526486516539 0.35938225648519195 SNLDEEVNVIPPHT(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 4 SNLDEEVNVIPPHTPVR 17 0 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 SNLDEEVNVIPPHT(1)PVR;SNLDEEVNVIPPHT(1)PVR;SNLDEEVNVIPPHT(1)PVR;SNLDEEVNVIPPHT(1)PVR 210.66 2.1905e-17 47367400.0 144123.9 174694.9 178001.9 154151.2 197426.0 179732.8 184472.6 191864.0 165870.0 149954.8 True False 142068.66675691365 174290.4046922725 163367.27088920402 165487.99348132825 185813.79083445028 172046.04712162024 194023.68859663574 200778.701873968 147187.97391146602 175874.28737778877 0.8077853157223683 0.9909942339546542 0.9288866117096531 0.940944784758956 1.0565148186517501 0.9782330873190961 1.1031953077931222 1.1416034991100377 0.836893079175907 1.0 17.424185052277508 -3.4047711734933968 0.5872617127378822 1.0252716454223572 6.329478844648381e-17 0.3033553381823043 0.08426448278088466 20.18209444593342 1.496104172605106 0.0394759254388743 20.1285360269267 0.0003937574886775222 3.4047711734933968 -1.0252716454223572 SNMS(ph)PHGLPAR ddPTM_PC-9_AZD4547_30min_R2 1 SNMSPHGLPAR 11 0 H0Y4T7;E7ESY4;Q13330-3;Q13330 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 S(0.005)NMS(0.995)PHGLPAR 65.219 0.03137 9545800.0 18817.0 16806.0 26820.0 41342.0 27490.0 27025.0 21461.0 30572.0 22655.0 26164.0 True False 24800.414582085672 22238.210840757743 26464.349276123303 31811.240627532832 23673.488011940346 25335.122477807534 23370.987424534116 25847.799874670945 23852.49704890083 25248.0063237018 0.9822721946486545 0.8807907664329685 1.0481758019554854 1.2599505964821363 0.9376379151852731 1.0034504171532923 0.9256567478991157 1.023756075758191 0.9447279418062042 1.0 14.623881851355826 SNMS(ph)PHGLPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNMSPHGLPAR 11 0 H0Y4T7;E7ESY4;Q13330-3;Q13330 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 S(0.021)NMS(0.979)PHGLPAR 65.956 0.030095 8065800.0 16012.0 17322.0 22197.0 21508.0 27250.0 23701.0 22766.0 21253.0 22464.0 19020.0 True False 18722.51534858449 19041.613682890144 22726.260662591285 20302.97648987682 21910.558115761767 22458.077836774064 20609.43966843338 20695.131269414887 22792.493502287314 22468.175437762835 0.8332904200630854 0.8474926562522036 1.0114867015144755 0.9036326312350708 0.9751819045767345 0.9995505820658762 0.9172725095333986 0.9210864196223095 1.014434552793254 1.0 14.455595352586723 -5.213808330880358 9.401028665764322 0.96228682631777 0.8399388498698296 0.6259614146334602 0.03921860148078501 0.32762258509481934 62.22486180593451 0.009719830537047522 0.025723965179138938 6.11211714180012e-06 5.213808330880358 -0.12234797644794038 SNNWS(ph)LEDVTASDK ddPTM_PC-9_AZD4547_30min_R2 2 SNNWSLEDVTASDK 14 0 Q14680-3;Q14680-4;Q14680-5;Q14680-2;Q14680-8;Q14680-6;Q14680 Q14680-3 MELK Maternal embryonic leucine zipper kinase 1 SNNWS(1)LEDVTASDK;SNNWS(0.685)LEDVT(0.313)AS(0.001)DK 151.11 3.3591e-05 8016300.0 26794.0 37557.0 52041.0 56921.0 65314.0 76773.0 71671.0 85812.0 66442.0 65621.0 True False 35313.93465017822 49696.565782835765 51350.90233701464 43798.74287068345 56246.27850170503 71972.37217349568 78049.58015487574 72551.72716358969 69953.98847596864 63323.62876347787 0.5576738942438128 0.7848028730074679 0.8109279796459083 0.691665081833474 0.8882352385677756 1.1365800346395498 1.2325506557181245 1.1457291469283921 1.1047059342928063 1.0 15.950456311099552 -6.595767630818616 2.832094058791346 1.1419739866738132 0.7248973087597637 0.8414536812699999 0.08430947936888351 0.09987099009222544 1.6250042620794822 0.029870334922040824 0.03046966322135842 2.536485413538792e-07 6.595767630818616 -0.41707667791404957 SNNWS(ph)LEDVTASDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNNWSLEDVTASDK 14 0 Q14680-3;Q14680-4;Q14680-5;Q14680-2;Q14680-8;Q14680-6;Q14680 Q14680-3 MELK Maternal embryonic leucine zipper kinase 1 S(0.001)NNWS(0.999)LEDVTASDK;SNNWS(0.999)LEDVTASDK 145.69 0.00018768 6566900.0 18578.4 30505.0 30494.0 40711.0 46206.0 38250.0 49420.0 35508.0 34731.0 36788.0 True False 21723.356179873976 33533.334799478354 31221.09260913901 38430.09465684283 37152.26599254637 36244.10266472334 44738.57983018436 34575.95262383586 35238.87517040335 43457.37318635224 0.4998773415668893 0.7716374078958246 0.7184302759225211 0.884317017783113 0.8549128322421018 0.8340150360515985 1.0294819164135416 0.7956291438870128 0.8108836909974599 1.0 15.407313351915953 -4.273531870847374 0.7545197994520568 0.8867812575006147 9.811788937515663e-15 0.6682585526869089 0.08097358342438923 3.3138796078249655 0.8385603356937564 0.030714725105919778 2.9661873096354032 5.3268213183024645e-05 4.273531870847374 -0.8867812575006049 SNNWS(ph)LEDVTASDK ddPTM_PC-9_Lapatinib_30min_R1 2 SNNWSLEDVTASDK 14 0 Q14680-3;Q14680-4;Q14680-5;Q14680-2;Q14680-8;Q14680-6;Q14680 Q14680-3 MELK Maternal embryonic leucine zipper kinase 1 S(0.004)NNWS(0.995)LEDVT(0.001)ASDK;SNNWS(0.759)LEDVT(0.219)AS(0.022)DK 117.2 0.0001336 6353700.0 19778.9 36075.0 36711.0 27797.0 41600.0 36878.0 34674.0 33675.0 32945.0 31166.0 True False 19496.849258993978 35991.4705539414 33692.763288558046 29841.284108073698 39153.169788746774 35300.81390681679 36469.250058815014 35239.663436631534 29234.38717377008 36553.00157391538 0.5333857253711044 0.9846378957733884 0.9217509325582052 0.8163839581745528 1.0711341915266106 0.9657432327529522 0.9977087650399651 0.9640703066579063 0.7997807543835759 1.0 15.157702258449534 -4.758258337053057 24.997732095405862 0.9468881882224996 0.533385156329279 0.7119980542576352 0.07887984805004929 48.27188224751587 379273.46172399365 0.019522309701765512 0.13564863057348545 1.7447839715590462e-05 4.758258337053057 -0.4135030318932207 SNPSAVAGNET(ph)PGASTK ddPTM_PC-9_Lapatinib_30min_R1 2 SNPSAVAGNETPGASTK 17 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 SNPSAVAGNET(0.998)PGAS(0.002)TK;SNPSAVAGNET(0.999)PGASTK 181.49 6.9702e-12 15870000.0 132533.0 106830.0 120832.0 119013.0 91119.0 82315.0 88260.0 69923.0 101578.0 74447.0 True False 130643.05511642418 106582.64169861565 110897.65938500839 127765.61303572952 85759.55956684668 78794.57933563713 92829.67094050332 73171.87784646123 90137.21597623978 87315.06475560818 1.496225828636668 1.220667269696664 1.2700862067205363 1.4632711250153798 0.9821851453341379 0.9024167771756272 1.0631575570645264 0.838021228653575 1.0323214697089294 1.0 16.413942967805013 -6.275595828328602 22.91885304074879 0.9628950086783147 1.3458217456594581 0.7975365214079856 0.096792484481795 111.73205557932322 180890.15667391176 0.028953637669986553 0.03303025449735724 5.301565991412716e-07 6.275595828328602 0.38292673698114343 SNPTPMEPT(ph)SPGEHQQNSK ddPTM_PC-9_AZD4547_30min_R2 3 SNPTPMEPTSPGEHQQNSK 19 0 E7EUR8;A0A1B0GVL4;P78312-4;P78312-6;P78312-2;P78312-5;P78312 E7EUR8 FAM193A Protein FAM193A 1 S(0.005)NPT(0.091)PMEPT(0.452)S(0.452)PGEHQQNSK;S(0.004)NPT(0.021)PMEPT(0.546)S(0.425)PGEHQQNS(0.004)K;SNPT(0.007)PMEPT(0.593)S(0.4)PGEHQQNSK 86.8 0.0012127000000000001 15052300.0 53103.0 43195.0 70367.0 94169.0 79727.0 75672.0 59237.0 79907.0 56406.0 70858.0 True False 69988.64938898319 57156.93902573667 69433.88760301894 72459.7919465469 68658.28223819453 70940.21787754478 64508.97824272527 67559.2092301887 59387.506004868716 68377.28298749667 1.0235658150058575 0.8359053844854916 1.0154525680073523 1.0597056329336272 1.0041095410408343 1.0374822569436806 0.9434270480522201 0.9880358838262474 0.8685268470776792 1.0 16.06122947710371 -10.19759028147292 12.497254187340769 0.9999999993317932 0.9768456249229058 0.010968939460020644 0.06913632011539474 0.0 0.0 0.06758851697092826 0.016392623208822885 6.344679935738513e-11 10.19759028147292 -0.023154374408887346 SNPTPMEPT(ph)SPGEHQQNSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SNPTPMEPTSPGEHQQNSK 19 0 E7EUR8;A0A1B0GVL4;P78312-4;P78312-6;P78312-2;P78312-5;P78312 E7EUR8 FAM193A Protein FAM193A 1 S(0.001)NPT(0.012)PMEPT(0.584)S(0.403)PGEHQQNSK;SNPT(0.002)PMEPT(0.499)S(0.499)PGEHQQNSK;SNPT(0.005)PMEPT(0.555)S(0.437)PGEHQQNS(0.003)K 83.87100000000001 0.0014022 15679100.0 42366.8 41077.4 51128.399999999994 60187.1 61972.0 60072.2 64225.0 65248.9 66179.0 49914.8 True False 49538.662457557395 45155.29280092089 52347.49496153677 56815.01191621097 49829.03146972431 56921.90808093577 58141.14305126655 63536.18551192421 67146.74267663248 58963.95811466059 0.8401515780406925 0.7658117644190788 0.8877880087314097 0.9635549195277765 0.8450760950075193 0.9653678263973752 0.9860454574336069 1.0775427488835216 1.138776039187528 1.0 15.847545752027317 -6.9788719825399115 0.7640407018304839 1.0865941795220693 0.8327584194747814 0.7126928669758257 0.05795478320230989 0.36255434963872524 0.44476451401527156 0.04536098571354907 0.03573716324019026 1.0498518490253706e-07 6.9788719825399115 -0.2538357600472879 SNPTPMEPT(ph)SPGEHQQNSK ddPTM_PC-9_Lapatinib_30min_R1 2 SNPTPMEPTSPGEHQQNSK 19 0 E7EUR8;A0A1B0GVL4;P78312-4;P78312-6;P78312-2;P78312-5;P78312 E7EUR8 FAM193A Protein FAM193A 1 S(0.001)NPT(0.006)PMEPT(0.496)S(0.496)PGEHQQNSK;S(0.001)NPT(0.01)PMEPT(0.494)S(0.494)PGEHQQNSK 70.837 0.006735 7889300.0 30768.0 25065.0 28899.0 22665.0 33572.0 31269.0 29449.0 28689.0 35475.0 23543.5 True False 30329.242677839844 25006.963532489022 26523.035773365995 24331.859708223565 31597.360965091506 29931.697761599156 30973.725124936343 30021.99567434365 31479.43193168897 27612.962605258184 1.0983697443629035 0.9056240683035975 0.9605284355947868 0.8811752674300215 1.14429449012018 1.0839727047578527 1.1217095958779224 1.0872428324162047 1.1400237048702089 1.0 14.753058063079164 -6.269589028896186 24.999153296900996 1.1012327581100332 0.957374645305957 0.5028290271619473 0.06549358098209765 464.7506528858093 1425627.2203337764 0.01921604684544074 0.02217060314496885 5.375402279027617e-07 6.269589028896186 -0.14385811280407623 SNPTPMEPTS(ph)PGEHQQNSK ddPTM_PC-9_AZD4547_30min_R2 1 SNPTPMEPTSPGEHQQNSK 19 0 E7EUR8;A0A1B0GVL4;P78312-4;P78312-6;P78312-2;P78312-5;P78312 E7EUR8 FAM193A Protein FAM193A 1 SNPTPMEPT(0.029)S(0.971)PGEHQQNSK 102.27 0.00024351 6030500.0 21891.0 22700.0 26120.0 40092.0 33701.0 29170.0 24417.0 33417.0 23887.0 23891.0 True False 28851.882638913634 30037.331077305746 25773.631733495185 30849.408815225328 29022.197871604294 27345.995288719558 26590.065698003335 28253.170496267117 25149.618053723 23054.583361854453 1.2514597286824645 1.3028789376000944 1.117939601378336 1.3381030717851965 1.258847206912605 1.1861413784629729 1.1533526882987877 1.2254903961098738 1.090872806460469 1.0 14.492765973418235 -8.518615138962515 0.5124198602679216 0.9916116677780027 1.2564554288410819 0.6185243350436379 0.060788445985574924 0.7019546185379981 0.4501024457835673 0.0702725399071058 0.03326636935539659 3.029596992858328e-09 8.518615138962515 0.26484376106307916 SNPTPMEPTS(ph)PGEHQQNSK ddPTM_PC-9_Lapatinib_30min_R1 1 SNPTPMEPTSPGEHQQNSK 19 0 E7EUR8;A0A1B0GVL4;P78312-4;P78312-6;P78312-2;P78312-5;P78312 E7EUR8 FAM193A Protein FAM193A 1 SNPT(0.005)PMEPT(0.475)S(0.519)PGEHQQNSK 90.1 0.00070541 4520300.0 15574.0 11098.0 14294.0 12887.0 16469.0 13386.0 12869.0 13092.0 16202.0 12570.0 True False 15351.911904078192 11072.303262859084 13118.802496435632 13834.752969771771 15500.32579929978 12813.511984290075 13535.293851499404 13700.302114695765 14377.160145376323 14742.707751527822 1.0413224058170207 0.751035932439998 0.8898502715741685 0.9384132957758755 1.0513893418048286 0.8691423719609568 0.9181009404528628 0.9292934748215416 0.9752048529813924 1.0 13.847713904045863 SNQQLVDIIEK ddPTM_PC-9_Lapatinib_30min_R1 1 SNQQLVDIIEK 11 0 K7EMD0;K7EPX6;K7EKR3;K7ENH2;B3KQ25;K7ESG5;K9J957;P61289;P61289-3;P61289-2 K7EMD0 PSME3 Proteasome activator complex subunit 3 0 113.61 0.0039673 0.0 18841.0 17079.0 16371.0 19514.0 16122.0 17104.0 13885.0 15866.0 18003.0 18527.0 False True 18572.323884983758 17039.454624830636 15025.039573887498 20949.124656795713 15173.735657071527 16372.50179137138 14603.897360173216 16603.192281680647 15975.312560005543 21729.36726432427 0.8547107543014465 0.7841670867612591 0.6914623601836728 0.9640927138817531 0.6983054532832202 0.7534734717403435 0.672081114122002 0.7640900022404294 0.7351945579305544 1.0 14.40735854496087 -10.869893166486511 3.548135170574491 1.0011171242637142 0.7670707277753943 0.4165127205927516 0.08213945341981257 53350947.12186322 72449582.45724995 610302.898108293 0.02026161737618652 1.3492947591808426e-11 10.869893166486511 -0.23404639648831993 SNQSLGWGDSSKPVS(ph)SPDWNK ddPTM_PC-9_AZD4547_30min_R2 2 SNQSLGWGDSSKPVSSPDWNK 21 1 Q8NDV7-2;Q8NDV7-6;Q8NDV7-5;Q8NDV7 Q8NDV7-2 TNRC6A Trinucleotide repeat-containing gene 6A protein 1 SNQSLGWGDS(0.018)S(0.013)KPVS(0.484)S(0.484)PDWNK;SNQSLGWGDS(0.001)S(0.001)KPVS(0.499)S(0.499)PDWNK 77.357 0.00057793 34610000.0 91433.0 100861.0 104359.0 100721.0 94977.0 121594.0 95600.0 101401.0 111867.0 108672.0 True False 120506.79207545523 133462.34580564476 102975.13147304073 77501.32957393776 81791.08297235555 113990.70795805866 104108.21479826017 85731.80541317252 117780.06123899309 104867.42635718259 1.1491346384815848 1.272676849635527 0.9819553606884885 0.7390410184184857 0.7799474614144901 1.0869982407101497 0.9927602728006645 0.817525597711978 1.1231329434731196 1.0 16.678207095814805 -5.360289241513748 5.127303664242785 0.924769308208166 1.2090435076600377 0.43697058921383525 0.12311251386131092 0.18825366662051102 7.595031720807078 0.03345351495884753 0.07224441934471808 4.362252080890391e-06 5.360289241513748 0.2842741994518716 SNQSLGWGDSSKPVS(ph)SPDWNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNQSLGWGDSSKPVSSPDWNK 21 1 Q8NDV7-2;Q8NDV7-6;Q8NDV7-5;Q8NDV7 Q8NDV7-2 TNRC6A Trinucleotide repeat-containing gene 6A protein 1 SNQSLGWGDS(0.014)S(0.014)KPVS(0.547)S(0.424)PDWNK 44.74 0.036802999999999995 11758000.0 10563.0 11960.0 10268.0 17511.0 17834.0 13037.0 13428.0 14646.0 13828.0 9076.1 True False 12351.107271240195 13147.30975911361 10512.828061606844 16529.915441427976 14339.555722440198 12353.316769673163 12156.002629698814 14261.558018719717 14030.208339994173 10721.525083631926 1.1519916406385207 1.2262536958650614 0.9805347634410994 1.5417503864877824 1.337454849994406 1.1521977212488568 1.1337941696612583 1.330179979757936 1.3086019228191208 1.0 13.388222516137986 -11.770739135159943 2.439389872729171 0.030680744525313927 1.2408953809651069 0.20018517961899063 0.14409622907910713 2371063.597793128 1455967.7959016294 13055157.531495562 0.036970417916554775 1.6953558330240693e-12 11.770739135159943 1.210214636439793 SNQSLGWGDSSKPVS(ph)SPDWNK ddPTM_PC-9_Lapatinib_30min_R1 2 SNQSLGWGDSSKPVSSPDWNK 21 1 Q8NDV7-2;Q8NDV7-6;Q8NDV7-5;Q8NDV7 Q8NDV7-2 TNRC6A Trinucleotide repeat-containing gene 6A protein 1 SNQS(0.007)LGWGDS(0.061)S(0.061)KPVS(0.435)S(0.435)PDWNK;SNQSLGWGDS(0.003)S(0.004)KPVS(0.496)S(0.496)PDWNK 66.536 0.0018698 25996000.0 37892.0 68659.0 59181.0 57865.0 81320.0 83306.0 76976.0 80056.0 71764.0 66432.0 True False 37351.65313145824 68500.02430389647 54315.366625266375 62120.585131981315 76536.9174812713 79743.19657577094 80961.44063353943 83775.69401879668 63681.182611577955 77914.68268492419 0.47939171211802234 0.8791670830631596 0.6971133649470144 0.7972898430862904 0.9823170016718881 1.023468155523921 1.0391037715052487 1.0752234512405523 0.8173194116582048 1.0 16.249607603095875 -6.127831061419805 2.2389297295500623 1.0014528825233346 0.701118333732029 0.6091258769997003 0.11071039840723412 0.21222046145233003 2.0903727079850274 0.034764332929293734 0.049047497817950515 7.4502172761285e-07 6.127831061419805 -0.3003345487913056 SNQSLGWGDSSKPVSS(ph)PDWNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNQSLGWGDSSKPVSSPDWNK 21 1 Q8NDV7-2;Q8NDV7-6;Q8NDV7-5;Q8NDV7 Q8NDV7-2 TNRC6A Trinucleotide repeat-containing gene 6A protein 1 SNQS(0.001)LGWGDSS(0.001)KPVS(0.086)S(0.91)PDWNK 76.241 0.0006383 10488000.0 24273.0 31677.0 33012.0 25051.0 31982.0 23331.0 39808.0 29801.0 25532.0 21685.0 True False 28381.93948639715 34821.68321400018 33799.13127870716 23647.473686437814 25715.356684707982 22107.481288121835 36037.098055038055 29018.755326769533 25905.357198201546 25616.318841634467 1.1079632347590744 1.3593554729418864 1.3194374838812937 0.9231409802724398 1.0038662012167239 0.8630233494826086 1.4068023699200132 1.1328230065439788 1.0112833681667523 1.0 14.644775549589264 -5.745938634061061 24.999490687615424 1.059555520459678 1.2719624616475995 0.29250875369966367 0.151310251746223 328.4096146672033 529652.3150553032 0.04302701328637116 0.07418413125287726 1.794987241143097e-06 5.745938634061061 0.21240694118792147 SNS(ph)APLIHGLSDTSPVFQAEAPSAR ddPTM_PC-9_AZD4547_30min_R2 3 SNSAPLIHGLSDTSPVFQAEAPSAR 25 0 Q96E09 Q96E09 FAM122A Protein FAM122A 1 S(0.189)NS(0.811)APLIHGLSDTSPVFQAEAPSAR;S(0.205)NS(0.795)APLIHGLSDTSPVFQAEAPSAR;S(0.186)NS(0.814)APLIHGLSDTSPVFQAEAPSAR 123.04 1.0455e-09 120065000.0 114629.0 100201.0 213280.0 305064.0 256161.0 240747.0 178830.0 265189.0 193321.0 201185.0 True False 151078.6375686825 132589.0137126483 210451.76784532348 234736.20799181663 220597.46681071792 225693.05203199704 194745.52356038554 224210.13348698537 203539.55338735643 194141.57438594796 0.778187969509006 0.6829501312741242 1.0840118532620495 1.2090980962437632 1.1362711336221905 1.1625178828689502 1.0031108698708548 1.1548795470323217 1.0484078643697694 1.0 17.56674957104515 -5.281810662861347 8.657307540671649 1.1095770964409957 0.7303998955570016 0.8199540469595029 0.06908613296992182 0.0845819991216377 33.57154447305213 0.01754609679861301 0.03801884918174358 5.2262398503924655e-06 5.281810662861347 -0.3791772008839941 SNS(ph)APLIHGLSDTSPVFQAEAPSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SNSAPLIHGLSDTSPVFQAEAPSAR 25 0 Q96E09 Q96E09 FAM122A Protein FAM122A 1 S(0.271)NS(0.729)APLIHGLSDTSPVFQAEAPSAR;S(0.182)NS(0.818)APLIHGLSDTSPVFQAEAPSAR;S(0.22)NS(0.78)APLIHGLSDTSPVFQAEAPSAR 111.23 1.1594000000000002e-07 88600000.0 42992.0 59197.0 60367.0 84268.0 87757.0 91406.0 82098.0 75992.0 79726.0 55700.0 True False 50269.69646929452 65073.68694065628 61806.37822312242 79546.73716054196 70561.64581889557 86612.50844893341 74321.0831019523 73997.29052017952 80891.84192322652 65797.96907904254 0.7640007309177881 0.9889923329165953 0.9393356525772846 1.2089542925706893 1.0723985376224983 1.3163401494183893 1.129534606344324 1.1246135945516373 1.2293972451649964 1.0 16.005755433953553 -4.98831587456042 0.9382178836111863 1.1657095328498928 0.662712936913453 0.6102380966765215 0.0954114662841053 0.9955253417506261 0.8646424049629003 0.031812484260670126 0.4772545393910395 1.0272688648803302e-05 4.98831587456042 -0.5029965959364397 SNS(ph)APLIHGLSDTSPVFQAEAPSAR ddPTM_PC-9_Lapatinib_30min_R1 4 SNSAPLIHGLSDTSPVFQAEAPSAR 25 0 Q96E09 Q96E09 FAM122A Protein FAM122A 1 S(0.18)NS(0.82)APLIHGLSDTSPVFQAEAPSAR;S(0.209)NS(0.791)APLIHGLSDTSPVFQAEAPSAR;S(0.164)NS(0.836)APLIHGLSDTSPVFQAEAPSAR;S(0.173)NS(0.827)APLIHGLSDTSPVFQAEAPSAR 144.21 8.0478e-10 134648000.0 181232.0 139433.0 219504.0 160978.0 199712.0 206345.0 171091.0 169327.0 216947.0 148516.0 True False 178647.5984461218 139110.1514552382 201457.22842994347 172816.85912686575 187965.33280889882 197520.10536368843 179949.2548253078 177194.55057860437 192512.1443068112 174186.7927148696 1.025609322393083 0.7986262866838063 1.1565585730699657 0.9921352614245196 1.07910209424766 1.1339556936846162 1.0330820840123678 1.0172674277817275 1.105205172598469 1.0 17.410275713717404 -5.266369229006698 24.99966101657318 1.0645521942349068 0.9121178058008946 0.410150890221074 0.07317408442705937 332.1712764017144 1684474.3568825028 0.017757560440251386 0.03890026205183693 5.415402872563895e-06 5.266369229006698 -0.15243438843401214 SNS(ph)AWQIYLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNSAWQIYLQR 11 0 Q8N4C8;Q8N4C8-4 Q8N4C8 MINK1 Misshapen-like kinase 1 1 S(0.003)NS(0.654)AWQIY(0.343)LQR;S(0.09)NS(0.91)AWQIYLQR 185.95 0.0010576 36885000.0 52771.0 43013.0 39371.0 47526.0 55497.0 45061.0 40439.0 49680.0 30880.0 20187.3 True False 61704.08802524053 47283.04637698613 40309.75395534897 44863.27230137091 44622.761238547915 42697.92183464311 36608.325166993636 48375.95264031107 31331.561580779577 23847.09768742114 2.5874883742262766 1.9827589502401786 1.6903421323514578 1.8812885697631614 1.8712030211578121 1.7904871441511054 1.5351270685784033 2.0285886892570746 1.3138521924748243 1.0 14.541526073170044 -1.5228787452803376 0.06059873911364867 1.9162133789469835e-14 5.520101685531264 0.6789954802215183 0.2312501027843496 217.95335646555063 0.9899093633381523 18.135956084032134 106.01251459366252 0.029999999999999995 1.5228787452803376 5.520101685531245 SNS(ph)DESNFSEK ddPTM_PC-9_AZD4547_30min_R2 2 SNSDESNFSEK 11 0 O95999;A0A087WWW9 O95999 BCL10 B-cell lymphoma/leukemia 10 1 S(0.002)NS(0.748)DES(0.198)NFS(0.053)EK;S(0.056)NS(0.882)DES(0.062)NFSEK 155.09 5.7858e-05 38361000.0 102092.0 93267.0 115824.0 138223.0 132038.0 126380.0 116864.0 149078.0 133726.0 133371.0 True False 134555.13235448208 123413.73381440855 114288.09808194275 106357.82287406198 113706.80284178193 118477.43862147356 127264.66960443418 126041.42057164034 140794.48335296026 128701.72188497316 1.0454804363436596 0.9589128413115503 0.8880075294104258 0.826390053810772 0.8834909213056769 0.9205583024550555 0.9888342420016467 0.9793297146738219 1.0939595934761073 1.0 16.973671829769273 -7.600932372160017 1.7031560904804945 1.0376139854936484 0.9147925526285144 0.3923596859163062 0.05961083376975211 0.4097395611205442 2.3131381752392177 0.04411488204895253 0.02015068096010925 2.5064995318846496e-08 7.600932372160017 -0.12282143286513392 SNS(ph)DESNFSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSDESNFSEK 11 0 O95999;A0A087WWW9 O95999 BCL10 B-cell lymphoma/leukemia 10 1 S(0.012)NS(0.982)DES(0.006)NFSEK 95.98100000000001 0.014772 0.0 5019.8 7296.0 5963.1 8003.1 9079.3 8149.9 9415.5 8735.7 8531.3 6512.4 True False 5869.552994430698 8020.298662415797 6105.282919182682 7554.712253400277 7300.276341300391 7722.504896921018 8523.595677683144 8506.397131239242 8656.054122866084 7693.046567869964 0.7629686032247494 1.0425386862875108 0.7936105501663564 0.9820182663332053 0.9489447745955447 1.0038292149659 1.1079610142075536 1.1057254179074179 1.1251789582319864 1.0 12.909339326014988 -6.730395867683828 1.1652602839731243 1.096341963057065 0.8900711570152843 0.5248297348865674 0.08168418789252037 0.35805560194241143 1.0303247858642923 0.03902664242403549 0.036271655862481 1.860390582145118e-07 6.730395867683828 -0.20627080604178072 SNS(ph)DNNLNASAPDWAVCSTATSHR ddPTM_PC-9_AZD4547_30min_R2 1 SNSDNNLNASAPDWAVCSTATSHR 24 0 Q9UPX8;Q9UPX8-3;A0A2R8Y2H5;A0A087X158 Q9UPX8 SHANK2 SH3 and multiple ankyrin repeat domains protein 2 1 S(0.226)NS(0.774)DNNLNASAPDWAVCSTATSHR 235.21 5.0399e-58 24164000.0 2520.1 4604.3 7208.5 8018.1 9061.6 8574.8 6324.4 9003.7 6416.5 3670.2 True False 3321.439378663662 6092.549933006122 7112.910580049771 6169.650923410112 7803.553254601625 8038.616400470085 6887.259348013771 7612.385049443109 6755.663090455625 3541.7074151219367 0.9378073876125955 1.7202296008396738 2.0083281158912114 1.7419990417807278 2.2033308627592993 2.2697008697409085 1.9446155598871373 2.1493545787945965 1.9074593970160112 1.0 11.790229318833312 -4.727435414114322 2.30436090073101 1.9647517759715354 0.5877826760627286 0.4060911106442596 0.34230746626657155 0.6353183238741184 3.5624819020585736 0.08357392699611298 1.8881786518645012 1.8731156217542585e-05 4.727435414114322 -1.376969099908807 SNS(ph)DNNLNASAPDWAVCSTATSHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNSDNNLNASAPDWAVCSTATSHR 24 0 Q9UPX8;Q9UPX8-3;A0A2R8Y2H5;A0A087X158 Q9UPX8 SHANK2 SH3 and multiple ankyrin repeat domains protein 2 1 S(0.037)NS(0.963)DNNLNASAPDWAVCSTATSHR;S(0.439)NS(0.561)DNNLNASAPDWAVCSTATSHR 156.52 1.6517e-07 20977000.0 1127.2 5687.5 10720.7 7202.6 13182.3 4982.5 5946.799999999999 9477.6 6602.700000000001 5787.4 True False 1318.012696785188 6252.117412621965 10976.322146481158 6799.061673144265 10599.322944932333 4721.208928810043 5383.476052896405 9228.823042347263 6699.2519964188195 6836.609806966809 0.192787468350479 0.9145055208870894 1.6055212241739756 0.9945077845770457 1.5503770500593954 0.6905775029019386 0.7874481950703701 1.3499122083788786 0.979908490549217 1.0 12.739065371882313 -4.803653799515723 3.9178107393301294 1.1234520559314427 0.1270341028591141 0.4821634096089813 0.2871081139706048 0.19055520470276877 5.264622582772971 0.07214957969562959 0.5159113009486911 1.5716151276641153e-05 4.803653799515723 -0.9964179530723286 SNS(ph)EDKLNSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SNSEDKLNSK 10 1 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 S(0.028)NS(0.972)EDKLNSK;SNS(1)EDKLNSK;S(0.003)NS(0.996)EDKLNS(0.001)K;S(0.007)NS(0.993)EDKLNSK;S(0.006)NS(0.994)EDKLNSK 134.68 0.00054042 43675900.0 63388.9 87359.0 87927.5 122044.0 142014.0 126167.0 116672.0 142769.0 115460.0 110868.6 True False 74119.38878215643 96031.42418448225 90024.02506690087 115206.27035198665 114187.37615602906 119550.5804156903 105619.98352786856 139021.46502625948 117148.38407114007 130968.19954464516 0.5659342423569792 0.7332423024701239 0.6873731591325188 0.879650714849405 0.8718710080236252 0.9128214393367853 0.8064551845035042 1.061490235871106 0.8944796101530424 1.0 16.99885702720212 -3.971908853515207 0.3417939015211575 0.9824500447931989 3.98585815524995e-11 0.7683855705457734 0.06745049392581795 5.367480916824742 0.3277527546517998 0.060863301000348556 2.4218017350327603 0.00010668199939558956 3.971908853515207 -0.9824500447533403 SNS(ph)EDKLNSK ddPTM_PC-9_Lapatinib_30min_R1 2 SNSEDKLNSK 10 1 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 S(0.007)NS(0.993)EDKLNSK;S(0.012)NS(0.988)EDKLNSK 126.09 0.0017272000000000001 5376100.0 26377.0 25554.0 21973.0 22213.7 22011.0 18942.5 18015.6 18826.0 19437.1 15175.8 True False 26000.85914305063 25494.83128303307 20166.46475823284 23847.369600730883 20716.35625529101 18132.373432124215 18948.35961699219 19700.72468769191 17247.88911626305 17798.916809517574 1.4608113190993315 1.4323810575596532 1.1330164062258705 1.3398213978942266 1.1639110670045607 1.018734658191578 1.064579368496176 1.1068496413870188 0.9690415040897391 1.0 14.11950182517441 -3.921427987866549 0.31883509687191 0.9834682667608392 2.238239363192069 0.8040135742743739 0.07550846250078087 5.372985006876527 0.28858871851891693 0.07696738649950836 2.8918085518876158 0.00011983178046638394 3.921427987866549 1.2547710964312297 SNS(ph)EVEDVGPTSHNR ddPTM_PC-9_AZD4547_30min_R2 2 SNSEVEDVGPTSHNR 15 0 Q13206 Q13206 DDX10 Probable ATP-dependent RNA helicase DDX10 1 SNS(1)EVEDVGPTSHNR;S(0.308)NS(0.692)EVEDVGPTSHNR 232.01 2.7602e-25 24404000.0 19711.8 23105.0 33447.0 48146.0 40305.0 33657.0 23258.8 33143.0 21403.9 27895.0 True False 25979.742369089476 30573.239407099092 33003.47092611841 37046.68354828492 34709.34646494201 31552.422469401245 25328.78814173404 28021.510900373512 22535.26645707212 26918.40454057718 0.9651293534104983 1.1357745724124386 1.2260559824921464 1.3762585183100369 1.2894280718837055 1.1721505419029825 0.9409468567705441 1.0409796337718862 0.8371694697990791 1.0 14.716305283197203 -7.212124110878687 4.713737695641409 0.9573444311291178 1.2080411402859381 0.5259928653548306 0.11114295128609762 0.18220392680471276 9.096290028561747 0.047875947459134024 0.03585912300566426 6.135866318603809e-08 7.212124110878687 0.2506967091568203 SNS(ph)EVEDVGPTSHNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNSEVEDVGPTSHNR 15 0 Q13206 Q13206 DDX10 Probable ATP-dependent RNA helicase DDX10 1 S(0.01)NS(0.99)EVEDVGPTSHNR;S(0.232)NS(0.768)EVEDVGPTSHNR 127.37 1.1893e-05 14325900.0 19013.5 24872.0 25765.7 23832.8 42823.7 68126.3 78135.0 80414.0 75860.0 57965.9 True False 22232.110016257247 27341.127786678404 26380.05200496138 22497.52548298011 34432.70339750262 64553.63689850301 70733.48715158741 78303.2177056758 76969.30898697996 68474.65881218808 0.32467646282452256 0.39928826606744405 0.3852527703324005 0.3285525751166749 0.5028532305935901 0.9427376202860737 1.032987799845704 1.1435357118090275 1.1240553851913444 1.0 16.063282551999773 -6.771486507808245 2.2791042940185284 1.086350254279803 0.36199859260475276 0.9824574003032427 0.044723030893161264 0.03601443234911922 0.38411292434494704 0.017998046801392067 0.016502497791952182 1.6924408225426683e-07 6.771486507808245 -0.7243516616750502 down SNS(ph)EVEDVGPTSHNR ddPTM_PC-9_Lapatinib_30min_R1 2 SNSEVEDVGPTSHNR 15 0 Q13206 Q13206 DDX10 Probable ATP-dependent RNA helicase DDX10 1 SNS(0.823)EVEDVGPT(0.175)S(0.002)HNR;SNS(1)EVEDVGPTSHNR 167.35 2.651e-05 10249600.0 12831.6 13390.400000000001 12943.3 11967.5 19831.4 27361.0 25512.0 26903.0 34689.0 25190.7 True False 12648.619030972746 13359.39535150372 11879.151836582854 12847.629872409681 18664.956042032525 26190.833811606193 26832.886528825304 28153.011594230105 30781.959528635925 29544.878930502146 0.4281154463596162 0.4521729597514605 0.4020714339201036 0.4348513291467843 0.6317492816923618 0.8864762611894397 0.9082076996133167 0.9528897261841518 1.041871235994696 1.0 14.850620466573853 -6.656437173448562 1.6150916375273312 0.9783116305533378 0.42006638478265734 0.9831195328876621 0.03302495116170835 0.04544452201529297 0.24496029553568055 0.014517839023137353 0.014351273479805953 2.205783209590032e-07 6.656437173448562 -0.5582452457706805 down SNS(ph)FIGVPNGEVEMPLK ddPTM_PC-9_AZD4547_30min_R2 2 SNSFIGVPNGEVEMPLK 17 0 Q9H7E2-2;Q9H7E2;Q9H7E2-3 Q9H7E2-2 TDRD3 Tudor domain-containing protein 3 1 S(0.223)NS(0.777)FIGVPNGEVEMPLK;S(0.251)NS(0.749)FIGVPNGEVEMPLK 145.17 9.043299999999999e-05 8998700.0 37280.0 40455.0 56255.0 59579.0 55041.0 42700.0 54934.0 67505.0 53956.0 52100.0 True False 49134.26452782882 53531.287609357 55509.02194363595 45843.9820363741 47399.50722681736 40029.96224985688 59823.01957874082 57073.65336058034 56808.004006642834 50275.9948580058 0.9772907461423377 1.06474845024042 1.1040859977094388 0.9118463426900054 0.9427860624277553 0.7962042792571936 1.1898923084008308 1.1352068421872732 1.1299230212566724 1.0 15.617582104314998 -7.294508128628487 24.999034206630295 1.1250227837004578 0.973379586167118 0.38696196586328657 0.09029266053878299 726.4068544106871 549140.0047441733 0.039944904605099654 0.026932794729928624 5.07565238913097e-08 7.294508128628487 -0.15164319753333988 SNS(ph)FIGVPNGEVEMPLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNSFIGVPNGEVEMPLK 17 0 Q9H7E2-2;Q9H7E2;Q9H7E2-3 Q9H7E2-2 TDRD3 Tudor domain-containing protein 3 1 S(0.012)NS(0.988)FIGVPNGEVEMPLK;S(0.169)NS(0.831)FIGVPNGEVEMPLK 148.19 6.543199999999999e-05 9839800.0 62748.0 60489.0 51175.0 61279.0 85170.0 77835.0 74692.0 88293.0 69930.0 57335.0 True False 73369.99707050831 66493.94816212563 52395.20608226828 57845.73629919849 68481.54989796055 73753.1955793135 67616.63303674878 85975.40230416626 70952.59395543765 67729.38163638973 1.083281661486305 0.9817592683645537 0.7735964040474469 0.8540715255566287 1.0111054942980122 1.088939449872185 0.9983353074113942 1.2693959434877415 1.0475895725189397 1.0 16.04749420368159 -6.541619908655225 3.517652753901322 1.091982489778763 0.917010675523696 0.3345005045697914 0.10368115437807258 0.266364541843804 7.029791229845113 0.03679024390770475 0.0385418050315777 2.8732941679068606e-07 6.541619908655225 -0.17497181425506714 SNS(ph)FIGVPNGEVEMPLK ddPTM_PC-9_Lapatinib_30min_R1 2 SNSFIGVPNGEVEMPLK 17 0 Q9H7E2-2;Q9H7E2;Q9H7E2-3 Q9H7E2-2 TDRD3 Tudor domain-containing protein 3 1 S(0.023)NS(0.977)FIGVPNGEVEMPLK;S(0.374)NS(0.626)FIGVPNGEVEMPLK 104.68 0.00068039 9455900.0 35190.0 50837.0 46792.0 37463.0 52215.0 51394.0 57271.0 55666.0 50628.0 60568.0 True False 34688.18414694435 50719.29004991595 42944.9423823434 40218.15399290447 49143.81635863975 49195.99842526548 60236.21215084486 58252.445578724044 44925.741503525 71037.098098213 0.4883108273790391 0.7139831356820563 0.6045424648817928 0.5661570513100139 0.6918049536693561 0.6925395285326703 0.847954290975748 0.8200285081773271 0.6324264744234415 1.0 16.116285027610953 -6.853541093608469 1.5769332578488637 0.8108082717475306 0.6041394119855046 0.49937772293406124 0.10073207130811995 0.35019288464532966 1.7991727938954258 0.04448144027242735 0.03749794753231614 1.4010670075634896e-07 6.853541093608469 -0.20666885976202598 SNS(ph)FNNPLGNR ddPTM_PC-9_AZD4547_30min_R2 1 SNSFNNPLGNR 11 0 O95835;O95835-2 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 S(0.392)NS(0.608)FNNPLGNR 132.06 0.00012744 16037000.0 29461.0 22768.0 27387.0 43252.0 30512.0 31801.0 25646.0 38540.0 28197.0 28515.0 True False 38828.98517313209 30127.310747493277 27023.83048565208 33280.91963673868 26275.93547545738 29812.478442803225 27928.44431711486 32584.5285610957 29687.435854683587 27516.698529290494 1.4111062463325712 1.0948737442256702 0.9820884019529533 1.2094808394732526 0.9549087237877623 1.0834322442813755 1.0149634879847986 1.1841728951026116 1.0788880004293546 1.0 14.748019764518835 -4.764890487439354 5.054163008182899 1.068438999743639 1.4314390451224164 0.6353748454754173 0.07844629916248806 0.10229235828831461 7.024723788009239 0.018553620945868682 0.13145513046638385 1.7183416329762794e-05 4.764890487439354 0.3630000453787774 SNS(ph)FNNPLGNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSFNNPLGNR 11 0 O95835;O95835-2 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 S(0.024)NS(0.976)FNNPLGNR 133.04 7.8018e-05 14072000.0 25034.0 24073.0 29248.0 30226.0 27379.0 24050.0 26366.0 29713.0 27373.0 22633.0 True False 29271.761755962027 26462.808347085454 29945.383243657696 28532.535214014184 22014.281491796017 22788.77566239469 23868.421606690437 28933.065233525824 27773.278340371715 26736.18373727058 1.094836946200247 0.9897750781161772 1.120032071066053 1.067188028568171 0.8233890710852584 0.8523570860499005 0.8927385389492799 1.0821688509416085 1.0387899265389702 1.0 14.706505932630991 -6.167045324104011 24.999352609799082 0.9447780575427527 1.066094242906596 0.3409956032356738 0.08143108707948629 70.68365752786481 18714.9562775912 0.026674271350165 0.034436346291124034 6.806983155364026e-07 6.167045324104011 0.12131618536384337 SNS(ph)FNNPLGNR ddPTM_PC-9_Lapatinib_30min_R1 2 SNSFNNPLGNR 11 0 O95835;O95835-2 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 S(0.433)NS(0.567)FNNPLGNR;S(0.368)NS(0.632)FNNPLGNR 121.21 0.00079051 33123000.0 82773.0 80943.0 95072.0 61770.0 103169.0 66713.0 74146.0 61420.0 79822.0 72463.0 True False 81592.64184129065 80755.58145662326 87255.54714853289 66312.77185867939 97100.80225805823 63859.84050559863 77984.91708083577 64273.79742473373 70831.60579707613 84988.13299912181 0.960047467357987 0.9501983230700892 1.0266791853097246 0.7802591905315135 1.1425218890155122 0.7513971451315268 0.9175977201621972 0.7562679065487635 0.8334293659305122 1.0 16.374973789522876 -6.794156060103792 24.999984881747523 0.8406214391982585 0.9631257105200175 0.2319219567799944 0.10783971717897264 272.3579025488914 208116.53538636447 0.03538396152926222 0.031207913557257622 1.6063639157985438e-07 6.794156060103792 0.122504271321759 SNS(ph)FSDER ddPTM_PC-9_AZD4547_30min_R2 1 SNSFSDER 8 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(0.002)NS(0.775)FS(0.224)DER 152.69 0.00017168 759050000.0 255870.0 278850.0 302980.0 250880.0 266370.0 320010.0 282760.0 398710.0 327210.0 289310.0 True False 337231.3375733787 368982.8092910446 298962.2872363848 193043.49205736123 229389.12338088534 299999.72411186626 307925.0922212975 337098.5309443293 344505.6525875455 279181.34495911037 1.2079293393431085 1.3216599746128697 1.0708533812679053 0.6914627196370692 0.8216491808021137 1.0745693776774554 1.1029572633744458 1.207453639116545 1.2339852171641437 1.0 18.09084301758127 -9.908896338154229 15.694490776256625 0.9999809114212236 1.0731813475139815 0.015797231004854972 0.1826628247774794 0.0 0.0 0.20125075344661048 0.048810477276206625 1.2333991984234534e-10 9.908896338154229 0.07320043609275795 SNS(ph)FSDER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SNSFSDER 8 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 SNS(0.536)FS(0.464)DER;SNS(0.536)FS(0.464)DER;S(0.007)NS(0.574)FS(0.419)DER;S(0.002)NS(0.809)FS(0.188)DER 126.66 0.0035431999999999994 1705378700.0 1667320.0 2357005.0 2269315.0 1507054.0 2166542.0 1248122.0 1289970.0 853665.0 1064620.0 1083267.0 True False 1949564.344928919 2590992.8794966154 2323424.076025063 1422618.6503149893 1742023.6477518762 1182668.285126794 1167774.703025963 831257.1982828317 1080188.0534368365 1279654.7319631432 1.5235080965457413 2.0247593470167713 1.815664818009662 1.111720696826184 1.361323179010485 0.9242088944667437 0.912570144006311 0.6495949083137323 0.8441246114721109 1.0 20.287323173551194 -6.1726945255100585 0.9747269900864599 0.8206548835012974 1.8499098640266267 0.7814071019213614 0.1996349642841019 0.24407860435074188 0.485318812809313 0.09029890943912175 0.1578779005236279 6.719012893604671e-07 6.1726945255100585 1.0292549805253293 SNS(ph)FSDEREFSGPSTPTGTLEFEGGEVSLEGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSFSDEREFSGPSTPTGTLEFEGGEVSLEGGK 33 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(0.07)NS(0.559)FS(0.282)DEREFS(0.034)GPS(0.01)T(0.01)PT(0.026)GT(0.008)LEFEGGEVSLEGGK 69.46 8.1868e-06 4205700.0 23272.0 12482.0 15696.0 25384.0 29520.0 24983.0 16482.0 17485.0 16593.0 16813.0 True False 27211.489957048354 13721.130469335803 16070.252167411487 23961.81677603836 23735.767911093095 23672.847499942058 14920.705640653556 17026.037276888877 16835.641234128096 19861.06380836524 1.3700922679472587 0.6908557669280851 0.8091335047543068 1.2064719698421154 1.1950904614231124 1.1919224331765823 0.7512541012213623 0.8572570654406596 0.8476706684279987 1.0 14.277655278848249 -7.2669356003340315 24.902023354424728 0.8521502172870642 1.0587386778648513 0.21673277649692624 0.19616886719272555 776.8346236269178 3519628.092138585 0.08479993920647551 0.05903170674801267 5.408345150302788e-08 7.2669356003340315 0.20658846057778713 SNS(ph)GLGGEVSGVMSKPNVDPQPWFQDGPK ddPTM_PC-9_Lapatinib_30min_R1 1 SNSGLGGEVSGVMSKPNVDPQPWFQDGPK 29 1 C9JRJ5;Q9UGP4 C9JRJ5 LIMD1 LIM domain-containing protein 1 1 S(0.062)NS(0.89)GLGGEVS(0.037)GVMS(0.011)KPNVDPQPWFQDGPK 82.26100000000001 5.259e-07 3519900.0 16745.0 11723.0 8943.1 10185.0 17183.0 15489.0 19023.0 13322.0 16420.0 16676.0 True False 16506.213229343088 11695.856113758968 8207.832839364315 10934.038876163995 16172.329723077799 14826.571576622518 20007.91785974615 13940.98875435206 14570.606689734544 19558.424380626733 0.843943914300839 0.5979958245176488 0.4196571604967548 0.5590449753710489 0.8268728302621875 0.7580657464058673 1.0229820904982845 0.7127869036404114 0.7449785527799065 1.0 14.255502531546382 -6.267735095346272 22.918319683271378 0.8345446951164348 0.5913984622413654 0.4221803356831909 0.13638314053464629 162.0348145953427 589855.2926655379 0.04294939217979048 0.05001715478694513 5.3983980577039e-07 6.267735095346272 -0.24314623287506942 SNS(ph)GRELTDEEILASVMIK ddPTM_PC-9_AZD4547_30min_R2 4 SNSGRELTDEEILASVMIK 19 1 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 S(0.008)NS(0.598)GRELT(0.393)DEEILASVMIK;S(0.105)NS(0.858)GRELT(0.037)DEEILASVMIK;S(0.244)NS(0.755)GRELT(0.002)DEEILASVMIK;S(0.021)NS(0.95)GRELT(0.029)DEEILASVMIK 92.8 0.0013044999999999999 32125900.0 92400.0 79076.0 123321.0 153385.0 141284.0 130834.0 105630.0 130508.0 101994.0 114387.0 True False 121781.27796060593 104635.77058453881 121685.68296349012 118024.4580246268 121669.15533935885 122652.92929737177 115030.86536757558 110340.98737549258 107385.19461512224 110382.34594669296 1.1032677093075904 0.9479393619254174 1.1024016741069798 1.069233100749865 1.1022519434232412 1.111164364604143 1.0421128884425732 0.9996253153450793 0.9728475481666412 1.0 16.752149926880968 -7.691523302953383 3.1950098142433654 0.9873645827861848 1.0699419885825094 0.39621517802951367 0.0450759196496436 0.26945421611771464 5.499678513399898 0.02586037968797963 0.012945131899828174 2.034589022911071e-08 7.691523302953383 0.08257740579632467 SNS(ph)GRELTDEEILASVMIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNSGRELTDEEILASVMIK 19 1 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 S(0.199)NS(0.794)GRELT(0.007)DEEILASVMIK;S(0.243)NS(0.712)GRELT(0.045)DEEILASVMIK 75.868 0.0059445 14966400.0 63963.0 58474.0 66125.0 94668.0 103636.0 97825.0 92987.0 91706.0 89219.0 76161.0 True False 74790.6725731645 64278.91227879679 67701.67078045908 89364.05887779726 83329.26975725073 92694.88478892976 84178.59819241904 89298.8146705386 90523.65908923504 89968.38640985578 0.8312994770457658 0.7144610995463537 0.7525051129853604 0.9932828901776066 0.9262061161977475 1.0303050714575814 0.9356464148299709 0.9925576998094985 1.0061718643796687 1.0 16.457130527859334 -5.760784151506136 24.999999999972726 0.9807177446812669 0.7609257703486614 0.8612591604330201 0.039952436774093866 5.469581062981385 208671.55017805277 0.010562554500840137 0.016981954257620457 1.7346659290306048e-06 5.760784151506136 -0.21979197433260556 SNS(ph)GRELTDEEILASVMIK ddPTM_PC-9_Lapatinib_30min_R1 1 SNSGRELTDEEILASVMIK 19 1 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 S(0.176)NS(0.639)GRELT(0.185)DEEILASVMIK 64.34899999999999 0.017294 3970400.0 27925.0 23007.0 33114.0 27904.0 33469.0 27915.0 24063.0 26267.0 33982.0 22716.0 True False 27526.784379182187 22953.72870504588 30391.494743736508 29956.153245015244 31500.419222585715 26721.140523043294 25308.864398836744 27487.460712397955 30154.589313675966 26642.43033283263 1.0331934450161526 0.8615478549927555 1.1407178085508116 1.124377651392372 1.1823403056351947 1.0029543172010724 0.9499457850753024 1.0317174660497828 1.1318257732859733 1.0 14.701438071162855 -5.2659465189582155 24.999938796576473 1.0708204580096128 0.9473706509805363 0.27353754521196916 0.08025243542578772 473.88972540144346 2628557.61944088 0.022193350918074083 0.048775424556734455 5.420676390211227e-06 5.2659465189582155 -0.12344980702907649 SNS(ph)IDGSNVTVTPGPGEQTVDVEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSIDGSNVTVTPGPGEQTVDVEPR 25 0 Q05GC8;Q96PN7-2;Q96PN7-3;Q96PN7-4;Q96PN7-5;Q96PN7 Q05GC8;Q96PN7 BCAR2;TRERF1 Transcriptional-regulating factor 1 1 S(0.19)NS(0.733)IDGS(0.069)NVT(0.008)VTPGPGEQTVDVEPR 61.04 0.016706 0.0 12704.0 10414.0 10826.0 16509.0 12068.0 16128.0 12428.0 12347.0 9947.2 8799.5 True False 14854.536284562651 11447.83309627167 11084.132897833631 15584.054252900152 9703.362030862862 15282.21928827864 11250.72986907186 12022.904332727878 10092.658981746454 10394.77969319633 1.4290381059528714 1.101305985711712 1.066317250098961 1.4992192920741116 0.9334841446629196 1.470182124040712 1.0823442344271879 1.1566290664723948 0.9709353425116242 1.0 13.34357156161286 -7.967967327917867 1.6154243120440819 0.98594477157855 1.229683085417322 0.22452370122610454 0.1790445962755053 0.6101626979812371 2.873842302707669 0.14632167913363844 0.0495927751620621 1.0765461994224465e-08 7.967967327917867 0.24373831383877198 SNS(ph)KPADGPSDSK ddPTM_PC-9_AZD4547_30min_R2 2 SNSKPADGPSDSK 13 1 Q68DA7-3;Q68DA7-5 Q68DA7-3 1 S(0.137)NS(0.77)KPADGPS(0.092)DS(0.001)K;S(0.036)NS(0.964)KPADGPS(0.001)DSK 63.54600000000001 0.021244 14874800.0 87251.0 103455.0 79848.0 78652.0 78731.0 80780.0 133818.0 127670.0 147677.0 111490.0 True False 114995.00306645904 136894.80557721006 78789.16334824357 60519.99656128665 67800.55964598295 75728.81383005691 145727.5427601836 107941.53506474032 155482.90473142912 107586.7690349148 1.0688582257651038 1.2724130188609346 0.7323313457129135 0.5625226698800322 0.6301942167626564 0.7038859379212408 1.3545117496082728 1.0032974875350182 1.445186114669646 1.0 16.715141141351815 -7.258278761361951 24.99531364655887 1.2010236315211515 0.8230944278820261 0.37579167562804017 0.23505826576187558 334.02377336361656 2641593.9068552437 0.10136076848108744 0.0751384023059491 5.517231900685095e-08 7.258278761361951 -0.3779292036391254 SNS(ph)KPADGPSDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSKPADGPSDSK 13 1 Q68DA7-3;Q68DA7-5 Q68DA7-3 1 S(0.127)NS(0.873)KPADGPSDSK 64.298 0.019995 6591500.0 61876.0 69295.0 36463.0 48067.0 58936.0 43026.0 65351.0 63677.0 48540.0 50148.0 True False 72350.38469329334 76174.14964529914 37332.41620669755 45373.96182531661 47387.91387561599 40769.640817055864 59160.48017973249 62005.54622135846 49249.805671342 59239.43542865043 1.2213213068249795 1.285868933323062 0.6301953409340255 0.7659418341345645 0.7999386478402764 0.6882179163601232 0.9986671843114873 1.0466937399503007 0.831368586060544 1.0 15.854270270882363 -5.24507630148915 24.869721596835294 0.8422331813688474 1.253595212711791 0.6113617202207433 0.130252566785926 528.0797785210818 802608.3718847014 0.03543693956016449 0.09313676600923734 5.687529974693801e-06 5.24507630148915 0.4113620313429437 SNS(ph)KPADGPSDSK ddPTM_PC-9_Lapatinib_30min_R1 2 SNSKPADGPSDSK 13 1 Q68DA7-3;Q68DA7-5 Q68DA7-3 1 S(0.077)NS(0.923)KPADGPSDSK;S(0.1)NS(0.899)KPADGPS(0.001)DSK 66.289 0.017827000000000003 17974600.0 67229.0 116029.0 71123.0 79318.0 138805.0 117008.0 195457.0 162148.0 107193.0 142925.0 True False 66270.30213171124 115760.34197930069 65275.54148271946 85151.31031709124 130640.76280112988 112003.84059897013 205576.80708155394 169681.98803037644 95119.79554766846 167629.39581440884 0.39533819119101593 0.6905730430924236 0.3894039059532815 0.5079736158648848 0.7793428006253093 0.668163480843034 1.2263768301662237 1.012244822609992 0.5674410212214837 1.0 17.354915639446475 -6.621894200828678 1.632929657840927 0.9383477090435894 0.5023166413449064 0.5148505248179442 0.18560727996468424 0.30910526054408877 1.6967440514716243 0.07631070706031223 0.07749727079357749 2.3883930522877434e-07 6.621894200828678 -0.43603106769868305 SNS(ph)LDKHQQSSTLGNSVVR ddPTM_PC-9_AZD4547_30min_R2 1 SNSLDKHQQSSTLGNSVVR 19 1 Q6ZSL5;A0A088AWN3;A0A0A0MSY4;Q9BZ29-3;Q9BZ29-5;Q9BZ29;Q9BZ29-4;X6RGR3 Q6ZSL5 DOCK9 Dedicator of cytokinesis protein 9 1 S(0.3)NS(0.696)LDKHQQS(0.001)S(0.001)T(0.001)LGNS(0.001)VVR 46.595 0.040081 5245200.0 3604.6 4583.7 6264.0 8939.5 6845.5 5968.6 6112.3 6733.1 4815.1 6247.4 True False 4750.787819662328 6065.291385861077 6180.935267175109 6878.636388898204 5895.120486931162 5595.38249846594 6656.2828589059145 5692.654106245812 5069.61635577852 6028.680427560566 0.7880311250109964 1.0060727979763433 1.0252550854940823 1.1409854065994276 0.9778459080334023 0.9281272354205786 1.104102786486445 0.9442620445133258 0.8409164188903409 1.0 12.55762654069342 -9.91963513226549 11.913527355822389 0.9999999994411067 0.9821602261719107 0.0 0.10224224888014527 0.0 0.0 0.10030484764590226 0.02432749891797306 1.203274928283073e-10 9.91963513226549 -0.017839773269196058 SNS(ph)LDKHQQSSTLGNSVVR ddPTM_PC-9_Lapatinib_30min_R1 1 SNSLDKHQQSSTLGNSVVR 19 1 Q6ZSL5;A0A088AWN3;A0A0A0MSY4;Q9BZ29-3;Q9BZ29-5;Q9BZ29;Q9BZ29-4;X6RGR3 Q6ZSL5 DOCK9 Dedicator of cytokinesis protein 9 1 S(0.089)NS(0.91)LDKHQQSSTLGNSVVR 58.635 0.011211 4342600.0 6697.8 5796.4 10835.0 5132.1 9154.0 7268.6 5697.6 7078.8 9139.2 5439.6 True False 6602.288143773907 5782.978791929758 9944.188124309505 5509.531754183728 8615.579717456447 6957.738921934171 5992.59384942909 7407.706890429913 8109.847055957488 6379.827612188604 1.0348693640499462 0.9064475003809552 1.5586922921414401 0.8635863050057679 1.350440833384974 1.0905841575784074 0.9393034128352141 1.1611139580445018 1.271170249249948 1.0 12.639301726457772 SNS(ph)LNNGQPK ddPTM_PC-9_AZD4547_30min_R2 1 SNSLNNGQPK 10 0 O60333-3 O60333-3 KIF1B Kinesin-like protein KIF1B 1 SNS(1)LNNGQPK 150.14 0.00015944 34913000.0 111950.0 79955.0 120620.0 154030.0 141690.0 140780.0 123630.0 145590.0 117150.0 146930.0 True False 147547.77129534417 105798.89014475684 119020.4999882921 118520.76323977737 122018.78924742914 131977.0043450786 134632.83049695494 123092.41082537448 123342.30983353479 141786.02542201162 1.0406369094287204 0.7461870084153728 0.8394374525559888 0.8359128686131967 0.8605840306493724 0.9308181391802368 0.949549365646114 0.8681561561444613 0.869918664173137 1.0 17.11335582049889 -6.718972437684145 7.456144438905329 0.9170390094000596 0.8547167229913072 0.11874631945663894 0.07726546567750116 0.4563822836320671 65.49793819167358 0.024939125943464584 0.02469835787784943 1.909974470442892e-07 6.718972437684145 -0.06232228640875237 SNS(ph)LNNGQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SNSLNNGQPK 10 0 O60333-3 O60333-3 KIF1B Kinesin-like protein KIF1B 1 S(0.012)NS(0.988)LNNGQPK;S(0.012)NS(0.988)LNNGQPK;S(0.239)NS(0.761)LNNGQPK;SNS(1)LNNGQPK 79.036 0.019577 58099000.0 278576.0 251672.0 320858.0 289194.0 365972.0 315563.0 327621.0 358836.0 312820.0 242684.0 True False 325733.4146731987 276656.33291769563 328508.4715807415 272991.39775959816 294262.4137519834 299014.3207630876 296586.3671093649 349416.9352181702 317394.40070270293 286680.6881145128 1.1362237785026053 0.965033029386294 1.1459037361090778 0.9522489971509815 1.026446586574545 1.0430221956340784 1.0345530041106057 1.218836669872223 1.1071356176455167 1.0 18.129085196944033 SNS(ph)LNNGQPK ddPTM_PC-9_Lapatinib_30min_R1 1 SNSLNNGQPK 10 0 O60333-3 O60333-3 KIF1B Kinesin-like protein KIF1B 1 S(0.175)NS(0.825)LNNGQPK 106.79 0.0022660999999999996 29599000.0 43078.0 32704.0 36682.0 34693.0 42063.0 40424.0 32163.0 36771.0 44449.0 34186.0 True False 42463.6998204623 32628.27589732777 33666.14755661478 37244.43895245534 39588.937039039796 38695.159752946485 33828.24276523237 38479.514899135196 39442.68555127957 40095.00455001831 1.059077067006915 0.8137740913989463 0.8396594023232105 0.9289047194393779 0.9873782902219852 0.9650868028877381 0.8437021804806584 0.959708455728748 0.9837306665491213 1.0 15.291134881569977 -7.990601705613111 24.894207721381537 0.9851500999722385 0.9161057673746699 0.14492844333345112 0.0706145540241356 356.2228941391019 943562.7862389602 0.03946721402480397 0.01892057606183219 1.0218762236463199e-08 7.990601705613111 -0.06904433259756859 SNS(ph)LPHPAGGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNSLPHPAGGGK 12 0 G5E9A7;Q09019 G5E9A7 DMWD Dystrophia myotonica WD repeat-containing protein 1 S(0.114)NS(0.886)LPHPAGGGK;S(0.132)NS(0.868)LPHPAGGGK 77.068 0.010183 15306800.0 87588.0 90965.0 109405.0 111260.0 129088.0 110158.0 114574.0 113620.0 102189.0 90749.0 True False 102414.91845814523 99995.40403325827 112013.63012077303 105026.46290978676 103794.1330659618 104381.12055792398 103720.72127607344 110637.59539034097 103683.3208024057 107201.07533131147 0.9553534620956522 0.9327835912486546 1.0448927846534009 0.9797146398503566 0.9682191409477908 0.9736947156110864 0.9675343363442784 1.0320567685390163 0.967185454828378 1.0 16.709959851943033 -5.1986649631023205 24.99999772707598 0.9900400763277626 0.94406844369773 0.33960017468487214 0.0264705754115118 256.37035177875003 102098.46671764445 0.006658359361950331 0.01761636252288431 6.3289991434411854e-06 5.1986649631023205 -0.045971632630032566 SNS(ph)LPHPAGGGK ddPTM_PC-9_Lapatinib_30min_R1 2 SNSLPHPAGGGK 12 0 G5E9A7;Q09019 G5E9A7 DMWD Dystrophia myotonica WD repeat-containing protein 1 S(0.251)NS(0.749)LPHPAGGGK;S(0.248)NS(0.752)LPHPAGGGK 75.02 0.025330000000000002 10859000.0 95279.0 75882.0 101786.0 78988.0 84778.0 85106.0 72507.0 74209.0 95420.0 68108.0 True False 93920.30398797133 75706.29989117618 93417.54798532231 84797.04101624353 79791.52471996086 81466.21477177575 76261.05768052436 77657.0210532735 84672.79478285438 79880.37705179451 1.1757619011622007 0.9477459006244819 1.1694680400012418 1.061550334962253 0.9988876826185229 1.0198526569166415 0.9546907575445798 0.972166430848475 1.0599949312701975 1.0 16.285553522164463 -6.181299925554033 4.076190480377556 0.9979414113112183 1.0868907178560105 0.314523285909757 0.06412327259412076 0.2910389059621671 9.097698900623808 0.01858030912160361 0.024217880607439894 6.58718824198297e-07 6.181299925554033 0.08894930654479227 SNS(ph)LPHSAVSNAGSK ddPTM_PC-9_AZD4547_30min_R2 2 SNSLPHSAVSNAGSK 15 0 A0A088AWN2;Q8TBZ3-4;Q8TBZ3-5;Q8TBZ3-6;Q8TBZ3;Q8TBZ3-2;Q8TBZ3-7 A0A088AWN2 WDR20 WD repeat-containing protein 20 1 S(0.001)NS(0.677)LPHS(0.301)AVS(0.021)NAGSK;S(0.081)NS(0.917)LPHS(0.002)AVSNAGSK 198.67 6.894600000000001e-10 43389400.0 33743.6 31589.8 83389.0 126256.0 98706.0 81111.0 70061.0 113723.0 80632.0 84309.0 True False 44473.36288951836 41800.58507779176 82283.20737459532 97149.62983575503 85002.37568958111 76039.11634773169 76296.29327385874 96149.7234445639 84894.04290650951 81357.36757166234 0.5466421077395935 0.5137897934194144 1.0113799134677934 1.1941097989703553 1.0448024343303404 0.9346309820159047 0.9377920592951138 1.1818194997505536 1.043470867364679 1.0 16.311985379138804 -5.2782152947986445 5.976149768220728 1.049195151184287 0.5271555041615352 0.8611824867586522 0.08246158554018107 0.05166073976314439 7.536057817571937 0.022971802115331095 0.05245291295916236 5.26968560114948e-06 5.2782152947986445 -0.5220396470227517 SNS(ph)LPHSAVSNAGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SNSLPHSAVSNAGSK 15 0 A0A088AWN2;Q8TBZ3-4;Q8TBZ3-5;Q8TBZ3-6;Q8TBZ3;Q8TBZ3-2;Q8TBZ3-7 A0A088AWN2 WDR20 WD repeat-containing protein 20 1 S(0.22)NS(0.712)LPHS(0.068)AVSNAGSK;S(0.224)NS(0.772)LPHS(0.004)AVSNAGSK;SNS(0.77)LPHS(0.228)AVS(0.001)NAGSK;S(0.018)NS(0.925)LPHS(0.043)AVS(0.013)NAGSK 202.79 3.3268e-11 161813900.0 264891.8 261516.0 440619.0 466313.0 579518.0 523754.0 485588.0 495033.0 447945.0 356727.8 True False 309732.74988846935 287477.5801809664 451125.02801686217 440186.9944171442 465965.6080047714 496287.4182237776 439589.58928732335 482038.90828082035 454495.3481963174 421399.72628428927 0.7350093760609471 0.6821968839795239 1.0705394424307701 1.044583009814725 1.105756788485469 1.1777117716706034 1.043165341286346 1.1438994337543116 1.0785373597744123 1.0 18.684829851505114 -5.274169965882937 8.506812367274941 1.0898019303552575 0.7082025511163766 0.899295553236263 0.05007777418545355 0.04353105851902699 24.64479819793344 0.012745532375989 0.028282494054841765 5.319000536395267e-06 5.274169965882937 -0.3815993792388809 SNS(ph)LPHSAVSNAGSK ddPTM_PC-9_Lapatinib_30min_R1 2 SNSLPHSAVSNAGSK 15 0 A0A088AWN2;Q8TBZ3-4;Q8TBZ3-5;Q8TBZ3-6;Q8TBZ3;Q8TBZ3-2;Q8TBZ3-7 A0A088AWN2 WDR20 WD repeat-containing protein 20 1 SNS(0.587)LPHS(0.018)AVS(0.394)NAGS(0.001)K;S(0.006)NS(0.642)LPHS(0.192)AVS(0.161)NAGS(0.001)K 144.3 0.00010519 14626400.0 37519.0 23497.0 41548.0 28187.0 36312.0 37733.0 31437.0 31744.0 39699.0 27045.0 True False 36983.97217985805 23442.594140151377 38132.083819918 30259.96600907557 34176.199552138794 36119.24754991912 33064.65403757766 33218.94212716945 35227.680570997065 31719.692214802708 1.1659625172087467 0.7390549057475205 1.202158065144239 0.9539804423119237 1.0774442362397736 1.1387010726750766 1.0424014777213788 1.0472655882728612 1.11059339203037 1.0 14.953091151778853 -5.291136666329188 24.998549354542718 1.070622324396641 0.9525083413693841 0.14412616065319472 0.1160346902875772 1078.738000036183 908057.2011340498 0.027758485203322508 0.05779663180436506 5.115208418383316e-06 5.291136666329188 -0.11811398302725695 SNS(ph)LSEQLAINTSPDAVK ddPTM_PC-9_AZD4547_30min_R2 1 SNSLSEQLAINTSPDAVK 18 0 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 S(0.026)NS(0.619)LS(0.355)EQLAINTSPDAVK 150.61 7.082800000000001e-05 8430900.0 22058.0 23225.0 28019.0 36283.0 30098.0 28420.0 20237.0 34664.0 24180.0 33218.0 True False 29071.985165097827 30732.027060371176 27647.449752710625 27918.51491676198 25919.412229297206 26642.892907281766 22038.053795736316 29307.47529947644 25458.10543555162 32055.047930772314 0.9069393759099391 0.9587265982799839 0.862499092574107 0.8709553321229218 0.8085906558391073 0.8311606011265711 0.6875064995482396 0.9142858049306408 0.7941995747606498 1.0 14.96826394548049 -5.585153271322934 1.740625765302072 0.828672510772581 0.9334823481912744 0.14770978000662582 0.07836851715898846 0.5889552886665488 3.5106002170541335 0.02279426301241157 0.05978701155831999 2.599242076076848e-06 5.585153271322934 0.10480983741869343 SNS(ph)LSTPRPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSLSTPRPTR 11 1 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 S(0.365)NS(0.622)LS(0.004)T(0.008)PRPT(0.001)R 60.901 0.029069 15712000.0 29399.0 31659.0 28768.0 39201.0 51253.0 39869.0 35001.0 32356.0 37132.0 34513.0 True False 34375.670043282254 34801.896292958016 29453.938223247555 37004.69506135677 41210.34257273896 37778.19945463675 31685.451894704227 31506.689284015803 37674.98525315762 40769.933695242304 0.8431622749313856 0.8536167008046732 0.7224426324412865 0.9076466824294854 1.0108022956522016 0.9266191045840558 0.7771769297334373 0.7727922620510054 0.9240874791403977 1.0 15.315217990101127 SNS(ph)LVSTFTMEK ddPTM_PC-9_AZD4547_30min_R2 2 SNSLVSTFTMEK 12 0 Q9HB21 Q9HB21 PLEKHA1 Pleckstrin homology domain-containing family A member 1 1 S(0.015)NS(0.931)LVS(0.048)T(0.005)FT(0.002)MEK;S(0.001)NS(0.967)LVS(0.031)TFTMEK 99.069 0.0030478000000000002 27630000.0 175472.0 172053.0 192078.0 237950.0 248060.0 188799.0 198058.0 268050.0 206870.0 205240.0 True False 231268.44595566439 227665.7675702063 189530.92021846416 183094.30379085257 213621.15082727975 176993.3686840918 215684.77831081417 226629.03167622435 217804.72586652456 198054.6100701938 1.1677003927033007 1.1495100643681955 0.9569629313414684 0.9244637311192148 1.0785972149376826 0.8936594236375637 1.0890167021831603 1.1442754682453657 1.0997205558069616 1.0 17.59553875734054 -10.306254452146568 12.351853722681621 1.0000059635107075 1.0514177937900409 0.02964964222368449 0.09283242870071086 0.0 0.0 0.09618578065082717 0.023328478429755994 4.940211563085361e-11 10.306254452146568 0.05141183027933338 SNS(ph)LVSTFTMEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SNSLVSTFTMEK 12 0 Q9HB21 Q9HB21 PLEKHA1 Pleckstrin homology domain-containing family A member 1 1 S(0.002)NS(0.91)LVS(0.076)T(0.009)FT(0.003)MEK;S(0.177)NS(0.823)LVSTFTMEK;S(0.041)NS(0.959)LVS(0.001)TFTMEK;S(0.002)NS(0.864)LVS(0.106)T(0.027)FTMEK 107.69 0.0015217 41007100.0 392453.0 382854.0 313230.0 344304.0 378847.0 258093.0 264362.0 296445.0 207598.0 207014.0 True False 458887.5415999277 420861.2149260609 320698.59113138966 325013.76312862843 304614.64992594504 244558.14873324052 239319.71754486437 288663.6328594409 210633.72801316943 244543.99947807746 1.8765029711598604 1.72100405581119 1.3114146812673653 1.329060471008469 1.2456435266294592 1.0000578597520007 0.9786366382149506 1.180415931184272 0.8613326373279179 1.0 17.899734539278413 -4.256231268738662 0.4487871357392613 0.9721045516426843 3.1267269384363963 0.9101429122863275 0.09378776506205781 2.1204457794911797 0.23275381890392885 0.06404841227747123 2.6754251732164858 5.5433044454396215e-05 4.256231268738662 2.154622386793712 SNS(ph)LVSTFTMEK ddPTM_PC-9_Lapatinib_30min_R1 4 SNSLVSTFTMEK 12 0 Q9HB21 Q9HB21 PLEKHA1 Pleckstrin homology domain-containing family A member 1 1 S(0.012)NS(0.955)LVS(0.005)T(0.002)FT(0.027)MEK;S(0.032)NS(0.923)LVS(0.02)T(0.02)FT(0.004)MEK;S(0.004)NS(0.946)LVS(0.024)T(0.024)FT(0.003)MEK;S(0.044)NS(0.947)LVS(0.007)T(0.002)FTMEK 73.80199999999999 0.019193 16412800.0 163179.0 224406.0 214654.0 213769.0 185250.0 181367.0 170731.0 199500.0 205479.0 209579.0 True False 160852.03753663597 223886.40169446304 197005.97670840175 229490.28537247924 174353.95921551329 173610.35619712665 179570.6157868012 208769.49831055643 182335.79123020495 245804.45090353565 0.6543902559346303 0.9108313574937087 0.8014744077425818 0.9336294950270905 0.7093197807225117 0.7062945994629646 0.7305425720597408 0.849331643683241 0.7417920650336859 1.0 17.907151513981077 -11.504520161882944 5.1123394973325205 1.1716918094303292 0.7868894819823815 0.3581710765284356 0.08734034197856416 0.060958078686566684 0.0002189024875983935 0.03016103714499199 0.020480408414802243 3.129535181238155e-12 11.504520161882944 -0.38480232744794773 SNS(ph)MLELAPK ddPTM_PC-9_AZD4547_30min_R2 6 SNSMLELAPK 10 0 Q9P2M7-2;Q9P2M7;A6PVU7;A2A3M4 Q9P2M7-2 CGN Cingulin 1 S(0.005)NS(0.995)MLELAPK;S(0.043)NS(0.957)MLELAPK;S(0.008)NS(0.992)MLELAPK;S(0.013)NS(0.987)MLELAPK;S(0.088)NS(0.912)MLELAPK;S(0.201)NS(0.799)MLELAPK 88.09200000000001 0.010209000000000001 104814300.0 294213.0 373961.0 585245.0 829670.0 753125.0 665590.0 721043.0 781619.0 737402.0 755759.0 True False 387766.61398943333 494836.5800440676 577484.2689077099 638402.399773721 648566.5936337801 623970.5520815516 785214.4301546214 660837.7433678003 776379.5642839802 729300.1074451349 0.5316969105459852 0.6785088538894725 0.7918335168367624 0.8753630957359319 0.8893000110829844 0.8555744688800733 1.076668469041317 0.9061259372123635 1.0645542985092553 1.0 19.476153081071644 -4.331033561202356 0.4335331625293745 1.0099901526095016 1.8560665291401204e-18 0.8741114888570471 0.05682611193107526 2.458334140153124 0.2687059030856436 0.03976859586732775 1.3849974388404895 4.666233194260766e-05 4.331033561202356 -1.0099901526095016 SNS(ph)MLELAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SNSMLELAPK 10 0 Q9P2M7-2;Q9P2M7;A6PVU7;A2A3M4 Q9P2M7-2 CGN Cingulin 1 S(0.002)NS(0.998)MLELAPK;S(0.003)NS(0.997)MLELAPK;S(0.032)NS(0.968)MLELAPK;S(0.006)NS(0.994)MLELAPK 82.515 0.013040000000000001 50354100.0 144219.0 145245.0 189879.0 259511.0 270899.0 249930.0 251973.0 266178.0 223076.0 196782.0 True False 168632.42824491076 159663.9637092359 194406.43548011733 244971.44001601337 217818.28561474252 236823.2308233805 228104.2933134575 259191.10953890288 226338.0644816707 232457.01887454503 0.7254348742032185 0.6868537008788068 0.8363113164805609 1.0538354195629698 0.9370260647293989 1.0187828785294364 0.9812751381646314 1.115006596891729 0.9736770503962426 1.0 17.826604462103205 -5.5574269313328015 3.2393102064497543 1.012100102706287 0.70979990030175 0.8720609319029364 0.047532687532940446 0.07484809221929858 1.6125167026388179 0.013126167588395823 0.026564219521723977 2.7705951437854563e-06 5.5574269313328015 -0.30230020240453703 SNS(ph)MLELAPK ddPTM_PC-9_Lapatinib_30min_R1 7 SNSMLELAPK 10 0 Q9P2M7-2;Q9P2M7;A6PVU7;A2A3M4 Q9P2M7-2 CGN Cingulin 1 S(0.01)NS(0.99)MLELAPK;S(0.051)NS(0.949)MLELAPK;S(0.002)NS(0.998)MLELAPK;S(0.007)NS(0.993)MLELAPK;S(0.001)NS(0.999)MLELAPK;S(0.003)NS(0.997)MLELAPK;S(0.035)NS(0.965)MLELAPK 117.07 0.00098745 117980600.0 832980.0 720682.0 766890.0 729175.0 739140.0 645171.0 642733.0 597492.0 694960.0 567284.0 True False 821101.5524501749 719013.3051075704 703839.264481008 782800.9619564939 695665.2384051523 617578.5402970576 676010.569823278 625253.6595717833 616686.286546767 665338.2835415853 1.2341113877882754 1.0806732798844427 1.0578667752808129 1.176545798311284 1.0455812563529896 0.9282173528474819 1.0160403910998241 0.939753017432828 0.9268763000742352 1.0 19.343728523167464 -6.5287818336898 4.3406585008499325 0.9626095207524753 1.1269344435733915 0.7049253017881647 0.053179269731526986 0.11894853144581166 5.502729557654154 0.01757847273989369 0.018488813102972353 2.9594987870350044e-07 6.5287818336898 0.16432492282091615 SNS(ph)NSSSVITTEDNK ddPTM_PC-9_AZD4547_30min_R2 1 SNSNSSSVITTEDNK 15 0 C9JYJ6;Q4L180-6;Q4L180-5;Q4L180-3;Q4L180-7;Q4L180-2;Q4L180;H7C4M0 C9JYJ6 FILIP1L Filamin A-interacting protein 1-like 1 SNS(0.971)NS(0.027)S(0.001)SVITTEDNK 183.71 5.2442e-07 11713000.0 35484.0 35577.0 40922.0 65456.0 47979.0 49352.0 55896.0 69487.0 60894.0 52551.0 True False 46767.1738869495 47076.569503846134 40379.347542040196 50366.130485119 41317.94402782413 46266.01163828891 60870.63571509992 58749.38080240936 64112.73252243512 50711.2054852795 0.9222256390754727 0.9283267682822404 0.7962608491679725 0.9931952909251849 0.8147695096662205 0.912342966323667 1.200338961233519 1.1585088589436745 1.2642715137396179 1.0 15.630016949496559 -7.238129050871727 7.559708447987424 1.1691239944416527 0.8919797999116394 0.7096541937429384 0.08168793717055797 0.10219775336889798 26.926347490922762 0.029827761994302395 0.022524986087802974 5.779242913305584e-08 7.238129050871727 -0.27714419453001327 SNS(ph)NSSSVITTEDNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNSNSSSVITTEDNK 15 0 C9JYJ6;Q4L180-6;Q4L180-5;Q4L180-3;Q4L180-7;Q4L180-2;Q4L180;H7C4M0 C9JYJ6 FILIP1L Filamin A-interacting protein 1-like 1 S(0.001)NS(0.995)NS(0.003)SSVITTEDNK;S(0.007)NS(0.97)NS(0.01)S(0.01)S(0.001)VIT(0.001)TEDNK 180.93 9.636399999999999e-29 8939700.0 37788.0 52759.0 30758.0 54387.0 49057.0 42953.0 47125.0 52715.0 50043.0 34714.0 True False 44184.76205297966 57996.564847916015 31491.38737036456 51339.87271503303 39444.633008621066 40700.469065565005 42660.97884454548 51331.287106159376 50774.78420294536 41007.3734041272 1.077483349580558 1.4142960163861393 0.7679445123201941 1.2519668648142657 0.9618912340445377 0.9925158742663751 1.0403245880715652 1.251757497372244 1.2381866963914134 1.0 15.323595718966939 -10.429015049072634 9.18247675411437 0.9999998677882849 1.1079351907946229 0.03436629910302069 0.17549786744346624 0.0 0.0 0.16531509131918729 0.040094799001037566 3.7237880244626933e-11 10.429015049072634 0.10793532300633801 SNS(ph)NSSSVITTEDNK ddPTM_PC-9_Lapatinib_30min_R1 2 SNSNSSSVITTEDNK 15 0 C9JYJ6;Q4L180-6;Q4L180-5;Q4L180-3;Q4L180-7;Q4L180-2;Q4L180;H7C4M0 C9JYJ6 FILIP1L Filamin A-interacting protein 1-like 1 S(0.019)NS(0.979)NS(0.002)SSVITTEDNK;S(0.014)NS(0.981)NS(0.004)S(0.001)SVITTEDNK 210.43 2.5642e-13 24097000.0 68961.0 95236.0 76359.0 64085.0 109391.0 105790.0 133217.0 129788.0 103119.0 113593.0 True False 67977.6034941016 95015.48689328258 70081.05777426402 68798.024681293 102956.83645098074 101265.60830853475 140114.32442421297 135818.4242943887 91504.65232879038 133227.398696842 0.5102374148187353 0.7131827823906526 0.5260258659987272 0.516395466354803 0.7727902627991582 0.7600959659879266 1.0516930135597868 1.0194481437218674 0.6868305860794338 1.0 17.023531282816315 -6.696208211142289 1.7907003299643987 0.9339976561440749 0.5770679058034244 0.6525494393003302 0.11700062034694099 0.21869056370168663 1.4469317873961853 0.04731980703516597 0.04538774725686027 2.0127590537720244e-07 6.696208211142289 -0.35692975034065055 SNS(ph)PGTASSGSSR ddPTM_PC-9_AZD4547_30min_R2 2 SNSPGTASSGSSR 13 0 H0YAP0;Q96GY0 H0YAP0 ZC2HC1A Zinc finger C2HC domain-containing protein 1A 1 S(0.231)NS(0.768)PGT(0.001)ASSGSSR;S(0.043)NS(0.892)PGT(0.041)AS(0.023)SGSSR 151.49 0.00013396 16564000.0 24716.0 22569.1 24115.0 35806.0 31631.0 28547.0 22575.1 24086.7 25694.0 26321.0 True False 32575.173875263295 29864.12021219478 23795.219343538924 27551.47989718544 27239.58164080338 26761.951577205247 24584.240166236425 20364.65397230264 27052.132384659377 25399.509801488868 1.2825119118383066 1.1757754557312048 0.9368377393702336 1.084724867232297 1.0724451713318754 1.0536404752046244 0.9679021508043177 0.801773503955927 1.0650651369292818 1.0 14.632513033484473 -1.5228787452977006 0.5417608530100584 0.9740681295185548 14.341314535289774 0.5476805379536507 0.0837695787373167 101.27597081172516 0.9519425721220424 0.0441352871229852 1570.1468772155667 0.029999999998800604 1.5228787452977006 13.367246405771219 SNS(ph)PGTASSGSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SNSPGTASSGSSR 13 0 H0YAP0;Q96GY0 H0YAP0 ZC2HC1A Zinc finger C2HC domain-containing protein 1A 1 S(0.004)NS(0.993)PGT(0.003)ASSGSSR;S(0.005)NS(0.91)PGT(0.084)ASSGSSR;S(0.003)NS(0.976)PGT(0.015)AS(0.003)S(0.003)GSSR 189.8 2.0531e-05 12211400.0 32093.0 37763.0 32441.3 27951.7 44148.0 39857.1 30933.199999999997 32659.6 34145.1 27908.9 True False 37525.71103435683 41511.86107302739 33214.82362631536 26385.65686963408 35497.516319069735 37766.92351158551 28002.983359025868 31802.320105706607 34644.40749131724 32968.56264326917 1.1382270874347031 1.2591346951397169 1.007469569896353 0.8003277896927348 1.0767080355660235 1.1455435264265599 0.8493844169679908 0.964625617738277 1.0508316017953607 1.0 15.008803369602015 -5.325675219683374 6.534195847897813 0.9820119129219992 1.1980236132292907 0.4194682269812091 0.09970133303074785 0.2033399362007828 16.880388310847227 0.026899904557677733 0.05710660631270782 4.724161982399495e-06 5.325675219683374 0.21601170030729155 SNS(ph)PGTASSGSSR ddPTM_PC-9_Lapatinib_30min_R1 3 SNSPGTASSGSSR 13 0 H0YAP0;Q96GY0 H0YAP0 ZC2HC1A Zinc finger C2HC domain-containing protein 1A 1 S(0.005)NS(0.556)PGT(0.272)AS(0.134)S(0.033)GSSR;S(0.01)NS(0.984)PGT(0.006)ASSGSSR;S(0.023)NS(0.939)PGT(0.023)AS(0.008)S(0.003)GS(0.003)S(0.002)R 140.49 7.3007e-05 16821400.0 19299.699999999997 25159.199999999997 27501.4 19583.8 23363.7 22131.899999999998 25651.7 24523.4 27006.4 17144.2 True False 19024.482738868486 25100.945418176652 25240.34105047397 21024.05798164168 21989.493100801537 21185.370228978754 26979.819511267953 25662.846691073195 23964.654842000422 20107.552126789447 0.9461361889755849 1.2483342208888006 1.2552667222404494 1.0455801804751341 1.0935937384195447 1.0536026511528134 1.3417754354754368 1.2762790084667932 1.1918235840389606 1.0 14.295449839636493 -7.242628537015964 24.645091408805115 1.225492781824358 1.1168325484635777 0.11786269258112747 0.119703986164862 1297.1768738739586 1699501.8056483145 0.045590098515206415 0.03525230963101335 5.719676458119557e-08 7.242628537015964 -0.10866023336078023 SNS(ph)PLPSIQLQPQSPSASKK ddPTM_PC-9_AZD4547_30min_R2 1 SNSPLPSIQLQPQSPSASKK 20 1 Q08174-2;Q08174 Q08174-2 PCDH1 Protocadherin-1 1 S(0.151)NS(0.543)PLPS(0.306)IQLQPQSPSASKK 54.658 0.010998 5432500.0 6251.6 7205.1 13511.0 15952.0 16554.0 9481.6 12899.0 13730.0 10651.0 10551.0 True False 8239.478758642015 9534.007671590123 13331.835312069417 12274.512855943196 14255.762842839598 8888.714053120442 14046.986011325922 11608.343984012565 11213.990115552533 10181.61270147445 0.809250852514633 0.9363946509386922 1.3094031076372377 1.2055568421067187 1.4001478214522096 0.873016320079944 1.3796425402521653 1.1401282217630908 1.1013962565997604 1.0 13.313678472608228 -5.083013588991419 4.588357567752141 1.1858433590285604 0.8337181087501129 0.38721183066410325 0.15564213471751298 0.18850410629765474 6.908652491060697 0.03806946176707052 0.115843298455451 8.260121034118138e-06 5.083013588991419 -0.35212525027844754 SNS(ph)PLPVPPSK ddPTM_PC-9_AZD4547_30min_R2 5 SNSPLPVPPSK 11 0 Q13247-3;Q13247 Q13247-3 SRSF6 Serine/arginine-rich splicing factor 6 1 S(0.006)NS(0.957)PLPVPPS(0.037)K;S(0.006)NS(0.994)PLPVPPSK;S(0.012)NS(0.985)PLPVPPS(0.003)K;S(0.001)NS(0.999)PLPVPPSK;S(0.4)NS(0.6)PLPVPPSK 173.59 0.00017779 1518724000.0 4114131.0 4015337.0 4608690.0 5474245.0 5304449.0 4927907.0 4476421.0 5414914.0 4609877.0 4845600.0 True False 5422339.078759147 5313216.161055315 4547575.759335443 4212242.391492154 4568017.817804609 4619764.196271783 4874813.797023455 4578163.463644972 4853545.686969582 4675957.018885857 1.159621240498727 1.1362842172405807 0.9725443884467091 0.9008300064519856 0.9769161263362154 0.9879826049753845 1.0425275034253798 0.9790858737909899 1.0379791061736574 1.0 22.15683023808912 -5.236404855900953 6.393350431102012 0.9849401511588368 1.1499303804715597 0.7479211520931738 0.03731997741007939 0.09126467781160132 14.16783043754946 0.010390913346868817 0.026768199409955385 5.802232723965823e-06 5.236404855900953 0.1649902293127229 SNS(ph)PLPVPPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SNSPLPVPPSK 11 0 Q13247-3;Q13247 Q13247-3 SRSF6 Serine/arginine-rich splicing factor 6 1 S(0.02)NS(0.792)PLPVPPS(0.187)K;S(0.007)NS(0.911)PLPVPPS(0.082)K;S(0.049)NS(0.872)PLPVPPS(0.079)K;SNS(1)PLPVPPSK;S(0.103)NS(0.897)PLPVPPSK 166.64 0.00026335 792585000.0 1993750.0 2683362.0 2399901.0 2479007.0 2707119.0 2466903.0 2612946.0 2311835.0 2272730.0 2030808.0 True False 2331252.496642541 2949748.445638349 2457123.7415152243 2340116.2748391354 2176678.4651663383 2337534.2639454673 2365428.838789168 2251151.780841661 2305964.3766672653 2398977.414532723 0.9717692557337505 1.229585750899162 1.024237963488217 0.9754640709257979 0.9073359557202483 0.9743877744679711 0.9860154682823099 0.9383797309655558 0.9612280477081628 1.0 21.193988144589945 -5.530865228493572 4.879226344879167 0.9614789696634221 1.1073893527294973 0.4304397303831856 0.06284132406836539 0.13906353585093745 9.210665401278776 0.01592655763346145 0.030415396944748454 2.945335496935078e-06 5.530865228493572 0.1459103830660753 SNS(ph)PLPVPPSK ddPTM_PC-9_Lapatinib_30min_R1 1 SNSPLPVPPSK 11 0 Q13247-3;Q13247 Q13247-3 SRSF6 Serine/arginine-rich splicing factor 6 1 S(0.08)NS(0.92)PLPVPPSK 147.7 0.00026335 378410000.0 1340600.0 1213900.0 1211500.0 1129900.0 1357900.0 1324800.0 1261000.0 1252400.0 1322100.0 1116100.0 True False 1321482.798164067 1211089.2891317937 1111895.1465252414 1212996.6152359052 1278030.9917341159 1268141.3922596374 1326288.409879613 1310591.0761109851 1173191.1756697963 1309016.3978902337 1.0095234867140899 0.9251903116597539 0.8494126951482837 0.926647379811983 0.9763292452210243 0.9687742600501603 1.01319464906415 1.0012029476661175 0.8962387160013049 1.0 20.320051739186965 -6.250494485574158 5.752573094855411 0.9776699410675259 0.9216107796588767 0.19839128168774356 0.04689200616550325 0.2581047097198959 33.68044420992637 0.014680040249227531 0.01815421519483034 5.61701410477362e-07 6.250494485574158 -0.056059161408649194 SNS(ph)QSDSHDEEVSPTPPNPVVK ddPTM_PC-9_AZD4547_30min_R2 1 SNSQSDSHDEEVSPTPPNPVVK 22 0 C9J4C2;C9IZL8;C9JR00;C9JSK5;P31321 C9J4C2 PRKAR1B cAMP-dependent protein kinase type I-beta regulatory subunit 1 S(0.126)NS(0.407)QS(0.234)DS(0.234)HDEEVSPTPPNPVVK 149.93 2.1331e-05 19890000.0 78698.0 66438.0 183340.0 221360.0 206270.0 181490.0 124700.0 217970.0 142040.0 173520.0 True False 103722.32697991094 87912.7842340987 180908.79180777213 170328.87197790804 177632.97097937233 170141.4016095208 135798.0584240907 184287.74495231005 149547.94441959265 167445.1176153773 0.6194407365054496 0.5250244706210845 1.0804064901033483 1.0172220868759803 1.0608429407144413 1.0161024939546872 0.8110004063302692 1.1005859566214429 0.893116183674614 1.0 17.3533287848214 -5.25855906266303 24.998680539908307 0.9979851312978644 0.5722325644580427 0.7998181728282977 0.085083314026004 96.43396952361192 836952.906397315 0.021431424885194412 0.05176037416238267 5.513672131019956e-06 5.25855906266303 -0.42575256683982166 SNS(ph)QSDSHDEEVSPTPPNPVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSQSDSHDEEVSPTPPNPVVK 22 0 C9J4C2;C9IZL8;C9JR00;C9JSK5;P31321 C9J4C2 PRKAR1B cAMP-dependent protein kinase type I-beta regulatory subunit 1 S(0.094)NS(0.368)QS(0.269)DS(0.269)HDEEVSPTPPNPVVK 91.76700000000001 0.00011149 8616700.0 34610.0 40882.0 47738.0 61348.0 76280.0 72019.0 59841.0 66026.0 64581.0 42883.0 True False 40468.789421340785 44940.49478027447 48876.254967373185 57910.87045289957 61333.48158056173 68242.19685779628 54172.42726867796 64292.88746032962 65525.374949751495 50657.348438358764 0.7988730296569767 0.8871466068730243 0.9648403730970471 1.1431879527481998 1.2107519140129093 1.347133218803097 1.0693893174175202 1.2691719847627427 1.2935018703058363 1.0 15.628483943474219 -5.625508927680002 1.6405730626858503 1.2137433194253464 0.8258096291275684 0.6849280758846304 0.09825885368819297 0.2106334681508564 1.1212170144717462 0.029533771495331502 0.0763041568313861 2.3685964406556402e-06 5.625508927680002 -0.387933690297778 SNS(ph)SEALLVDR ddPTM_PC-9_AZD4547_30min_R2 1 SNSSEALLVDR 11 0 Q96HB5-2;Q96HB5;Q96HB5-5;Q96HB5-3;Q96HB5-4 Q96HB5-2 CCDC120 Coiled-coil domain-containing protein 120 1 S(0.014)NS(0.959)S(0.028)EALLVDR 168.5 0.0021966999999999998 13701000.0 9780.2 11668.0 21821.0 31229.0 24419.0 26303.0 18949.0 25316.0 24372.0 22010.0 True False 12890.100159202559 15439.452819823939 21531.639282411892 24029.63653324036 21028.843352621734 24658.269251943457 20635.42429092293 21403.993903806404 25660.254163575853 21239.436599322606 0.606894636725612 0.7269238403581926 1.0137575533947358 1.1313688299060976 0.9900848007094695 1.1609662589981267 0.9715617546833167 1.0077477245554172 1.208141941222407 1.0 14.374457877040685 -5.200961219378033 2.6845643665928893 1.0657526269973543 0.6199197967659881 0.8188370498900697 0.075352227350252 0.1085085695089842 1.4854280045015749 0.019559661567228513 0.06924991695500494 6.29562397550971e-06 5.200961219378033 -0.4458328302313662 SNS(ph)SEALLVDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSSEALLVDR 11 0 Q96HB5-2;Q96HB5;Q96HB5-5;Q96HB5-3;Q96HB5-4 Q96HB5-2 CCDC120 Coiled-coil domain-containing protein 120 1 S(0.186)NS(0.77)S(0.045)EALLVDR 139.66 0.00011345 12143000.0 7321.2 7625.7 8467.9 12591.0 14473.0 12571.0 12973.0 12680.0 8141.7 11642.0 True False 8560.534559708763 8382.729099504404 8669.806850689587 11885.567090572771 11637.119545299818 11911.75463001928 11744.103523613552 12347.163435570536 8260.756959916876 13752.602441978706 0.622466518306268 0.6095376591354668 0.6304120901674365 0.8642413056523062 0.8461758124977461 0.8661454935728828 0.8539549931121129 0.8978055962616804 0.6006686367011951 1.0 13.747417029086714 -5.755590632111755 20.795846684663307 0.8437941378745789 0.6196778765904288 0.5504687874479048 0.0936375637534467 12.613363094642377 44841.707342143 0.024475613822496717 0.04072281777228707 1.7555344967236113e-06 5.755590632111755 -0.22411626128415008 SNS(ph)SEALLVDR ddPTM_PC-9_Lapatinib_30min_R1 2 SNSSEALLVDR 11 0 Q96HB5-2;Q96HB5;Q96HB5-5;Q96HB5-3;Q96HB5-4 Q96HB5-2 CCDC120 Coiled-coil domain-containing protein 120 1 S(0.004)NS(0.912)S(0.085)EALLVDR;S(0.036)NS(0.93)S(0.034)EALLVDR 139.58 0.00011267 23887000.0 35321.0 26692.0 29908.0 25713.5 29556.0 26741.0 22647.2 22038.3 28913.0 24553.2 True False 34817.31606292189 26630.19631395159 27449.079688218615 27604.556567721444 27817.57418933174 25597.349766315623 23819.761202399346 23062.279872769617 25656.51347261237 28797.18790491752 1.2090526400661625 0.9247498888391152 0.9531861159099949 0.9585851458436184 0.9659823133140546 0.8888836594334449 0.8271558070547503 0.8008518036176516 0.8909381553964567 1.0 14.813640316435444 -1.833390003968608 1.0482448077211681 0.8950510716760967 199.9999999935018 0.6701559267021187 0.06145354433744978 647.9593756121137 1.4793331511993804 0.02055017241087601 309200.45501370606 0.014676077485179939 1.833390003968608 199.1049489218257 SNS(ph)SSEAVLGQEELSAQAK ddPTM_PC-9_AZD4547_30min_R2 1 SNSSSEAVLGQEELSAQAK 19 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 S(0.287)NS(0.69)S(0.022)S(0.002)EAVLGQEELSAQAK 244.72 1.2307e-53 7182100.0 52655.0 57086.0 81558.0 90410.0 84087.0 81611.0 68425.0 75273.0 74746.0 69582.0 True False 69398.19470796216 75537.93312242633 80476.48763094947 69567.37132057581 72412.9714972726 76507.85126868996 74514.69244321086 63641.28745146229 78696.92096301662 67145.95535911238 1.033542442531412 1.1249811357725372 1.198530681416956 1.0360619779480853 1.0784413016389591 1.1394260586435616 1.1097420841611194 0.9478052268538544 1.1720277199442162 1.0 16.035012878843375 -10.592996191855015 0.23573453278867335 0.9349383516668696 1.1130375557278704 0.12273921759424355 0.07056451765895021 34.61919183330148 1.8298998137007472 1.6111178943841653 0.13666583947505698 2.5527236863195467e-11 10.592996191855015 0.17809920406100088 SNS(ph)SSEAVLGQEELSAQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNSSSEAVLGQEELSAQAK 19 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 S(0.091)NS(0.659)S(0.202)S(0.048)EAVLGQEELSAQAK;S(0.079)NS(0.441)S(0.441)S(0.039)EAVLGQEELSAQAK 279.97 2.8214999999999993e-92 17332000.0 25282.5 30402.0 29366.0 39053.0 51280.0 54668.0 67434.0 66607.0 55073.0 55757.0 True False 29562.327897863317 33420.10964018162 30066.19681117517 36864.987021534274 41232.05211656011 51801.11384248618 61046.163340118466 64858.636825950074 55878.338437120256 65865.30272783095 0.44883006186156876 0.5074008355853221 0.45648005195413605 0.5597026885895906 0.6260056571354341 0.7864704434220715 0.9268334132217358 0.9847162943129462 0.8483729083888236 1.0 16.00723104561545 -6.743842446955861 1.2104241117856165 0.9520621806394373 0.47498647503961755 0.9559535280252092 0.043749867262486176 0.08266915923278423 0.2557193972420449 0.02122334997599767 0.019455796812200065 1.8036719570177435e-07 6.743842446955861 -0.4770757055998197 SNS(ph)SSEAVLGQEELSAQAK ddPTM_PC-9_Lapatinib_30min_R1 1 SNSSSEAVLGQEELSAQAK 19 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 S(0.034)NS(0.887)S(0.062)S(0.017)EAVLGQEELSAQAK 244.91 1.2016e-53 4171300.0 15927.0 12491.0 15104.0 12949.0 20736.0 29113.0 29484.0 28788.0 39054.0 26644.0 True False 15699.87805934592 12462.07785694475 13862.207423126049 13901.312656597695 19516.34924854455 27867.904855717698 31010.53725368002 30125.595575760915 34655.32726314815 31249.37989910164 0.5024060672575862 0.3987944047908295 0.4435994399851934 0.4448508322879498 0.6245355687555774 0.8917906513888567 0.9923568836824027 0.9640381880546361 1.1089924784121692 1.0 14.931539941312428 -6.7110544766285845 1.680574241540057 1.019736771420324 0.4369503037596324 0.9744855897260463 0.04231433502906864 0.049601933022589806 0.28993929737914476 0.0171911902635257 0.016287504517719997 1.9451160766522515e-07 6.7110544766285845 -0.5827864676606916 SNS(ph)TETLSPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSTETLSPAK 11 0 Q9P0K1-5;Q9P0K1 Q9P0K1-5 ADAM22 Disintegrin and metalloproteinase domain-containing protein 22 1 S(0.015)NS(0.951)T(0.032)ET(0.001)LSPAK 101.43 0.0092796 0.0 18049.0 23158.0 13873.0 16856.0 32586.0 17928.0 12041.0 15445.0 14500.0 15529.0 True False 21104.33921600059 25456.973194109807 14203.78493364548 15911.612967889321 26201.00722055827 16987.824119559747 10900.389310709224 15039.585115330206 14712.035068695073 18344.28477250364 1.1504585475926545 1.3877332100877227 0.7742893827583629 0.8673880265824991 1.428292656022824 0.9260554080049443 0.5942117365648337 0.8198512671299746 0.801995567074222 1.0 14.163043035824245 -6.995364078207225 24.99873438273278 0.7848781259983095 1.110412227542693 0.340275522656282 0.20874509600992813 151.5924428267359 817439.9123608532 0.07568706581842964 0.06650725976857115 1.0107317812676756e-07 6.995364078207225 0.32553410154438356 SNS(ph)TETLSPAK ddPTM_PC-9_Lapatinib_30min_R1 1 SNSTETLSPAK 11 0 Q9P0K1-5;Q9P0K1 Q9P0K1-5 ADAM22 Disintegrin and metalloproteinase domain-containing protein 22 1 SNS(0.935)T(0.065)ETLSPAK 141.73 0.00013395 5864000.0 45050.0 43437.0 29436.0 19891.0 16849.0 19515.0 20260.0 18947.0 32920.0 9899.8 True False 44407.5787388418 43336.42429526134 27015.885706245946 21353.85049443083 15857.974946408516 18680.388941686895 21308.96366705866 19827.346789424126 29212.20293703174 11610.967239345682 3.824623549738335 3.7323698708242588 2.3267558291524715 1.8391103905684771 1.3657755309713686 1.6088572602621174 1.8352444915053858 1.7076395429173103 2.5159146809097317 1.0 13.503200538943565 -5.365047496585605 2.280911923706105 1.7116568283381661 3.891807201554397 0.8363834527719641 0.3637890644771122 0.11605036346881517 1.144144921634083 0.10065765968515675 0.3002815615650489 4.314718863546802e-06 5.365047496585605 2.180150373216231 SNS(ph)TSSMSSGLPEQDR ddPTM_PC-9_AZD4547_30min_R2 2 SNSTSSMSSGLPEQDR 16 0 P42684-2;P42684-6;P42684-3;P42684 P42684-2 ABL2 Abelson tyrosine-protein kinase 2 1 S(0.003)NS(0.625)T(0.217)S(0.128)S(0.016)MS(0.01)S(0.001)GLPEQDR;S(0.003)NS(0.891)T(0.094)S(0.01)S(0.001)MS(0.001)S(0.001)GLPEQDR 121.51 6.5011e-05 5561400.0 25162.0 25316.0 35169.0 44717.0 40877.0 37136.0 29604.0 41051.0 30115.0 35188.0 True False 33162.99259788702 33498.90191863755 34702.636080983604 34408.18652076303 35201.9341383807 34813.88004943054 32238.698649452865 34707.511208135424 31706.817419008974 33956.07883039365 0.9766437627716678 0.9865362277535153 1.021985967647175 1.013314484650233 1.0366901995430609 1.0252620811525823 0.9494234835088325 1.022129539205486 0.9337596834245953 1.0 15.051382248965588 -8.246351339976618 24.98785944033684 0.9668798333828775 1.004305655937012 0.20614546099127018 0.029131169600816964 1095.8326746787723 1814858.7182729747 0.01994158005512243 0.007470632204796888 5.670856530578386e-09 8.246351339976618 0.037425822554134514 SNS(ph)TTQVSQPR ddPTM_PC-9_AZD4547_30min_R2 3 SNSTTQVSQPR 11 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 S(0.027)NS(0.915)T(0.033)T(0.024)QVSQPR;S(0.001)NS(0.909)T(0.082)T(0.007)QVSQPR;S(0.003)NS(0.914)T(0.083)TQVSQPR 143.58 0.00015421 194817800.0 25960.7 22767.1 32710.0 46391.0 36660.0 33737.0 28558.2 45389.0 32827.0 35914.0 True False 34215.66258389498 30126.11984009372 32276.244027665663 35696.27168380522 31570.391797662167 31627.420056754607 31099.824475435915 38375.172985458565 34562.168202351255 34656.661791370854 0.9872751966092221 0.8692735619330425 0.9313142801221008 1.0299974042131554 0.910947280142338 0.9125928009785842 0.8973693041370605 1.1072957117587585 0.9972734365015177 1.0 15.080845077066224 -7.750594294887072 24.999924246041957 1.0392134420486052 0.9334782582570744 0.4449287077747648 0.05149423582260819 178.88238889386693 412359.32038474234 0.024418435215279675 0.013915654794333026 1.775847650830954e-08 7.750594294887072 -0.1057351837915308 SNS(ph)TTQVSQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SNSTTQVSQPR 11 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 S(0.111)NS(0.883)T(0.006)TQVSQPR;S(0.215)NS(0.719)T(0.065)T(0.002)QVSQPR;SNS(0.945)T(0.054)T(0.001)QVSQPR;S(0.024)NS(0.97)T(0.006)TQVSQPR;S(0.034)NS(0.481)T(0.481)T(0.004)QVSQPR 149.32 5.7711000000000004e-05 187639700.0 48474.4 46912.3 53666.4 50019.4 64200.0 58033.50000000001 56041.299999999996 60443.200000000004 53209.5 47884.0 True False 56680.158506958745 51569.44311141018 54946.0105069554 47216.975183082766 51620.47086355614 54990.121097862015 50732.662360123686 58856.630044864134 53987.58827501587 56564.99015046455 1.0020360360036806 0.9116848243804857 0.9713784155322467 0.8347385026937018 0.9125869327696187 0.9721582369516314 0.8968915618154144 1.0405133968609162 0.9544346800274743 1.0 15.787621779536938 -7.755448321529702 24.9993327710717 0.9981055308961654 0.9271911705849242 0.3040033796478202 0.04817132625096792 169.8189162319265 708624.9263299996 0.02299027393478165 0.012831174443583155 1.7561098484343447e-08 7.755448321529702 -0.07091436031124121 SNS(ph)TTQVSQPR ddPTM_PC-9_Lapatinib_30min_R1 2 SNSTTQVSQPR 11 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 S(0.003)NS(0.906)T(0.088)T(0.003)QVSQPR;S(0.004)NS(0.905)T(0.083)T(0.008)QVSQPR 116.9 0.0012151 93077700.0 17816.6 14274.2 17530.3 14321.3 16195.9 15450.3 15452.9 15500.8 18097.9 13208.3 True False 17562.53201683572 14241.148966904242 16089.026402914891 15374.536176456302 15243.289004364515 14789.5266854084 16252.975550379606 16221.0237564525 16059.523922664233 15491.337056046548 1.1337002063344008 0.9192975993860817 1.0385821665816157 0.9924602454153784 0.9839879507634097 0.9546965915144027 1.0491654459248743 1.0471028871017394 1.036677716362508 1.0 13.919174047942972 -7.312925794870291 24.99889130014709 1.037161764256024 1.0001136184637642 0.06096643535356849 0.05464604523478521 865.6975180108753 420330.0420412138 0.021538898696820852 0.014521561086378936 4.8649032209067344e-08 7.312925794870291 -0.03704814579225979 SNS(ph)VGIQDAFNDGSDSTFQKR ddPTM_PC-9_AZD4547_30min_R2 2 SNSVGIQDAFNDGSDSTFQKR 21 1 O14497-2;O14497;H0Y488;A0A1B0GTU5;O14497-3;A0A087WUV6 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 S(0.081)NS(0.919)VGIQDAFNDGSDSTFQKR;S(0.301)NS(0.657)VGIQDAFNDGS(0.042)DSTFQKR 113.02 4.8226e-06 36819600.0 26909.0 24391.0 41188.0 77384.0 53870.0 42566.0 40119.0 44898.0 36958.0 44049.0 True False 35465.502258029635 32274.91375799844 40641.820208238896 59544.3143708819 46391.080363885994 39904.341291039986 43689.51327919877 37960.04575340103 38911.52442874763 42506.8579174721 0.8343477734083898 0.7592872147986289 0.9561238397612402 1.4008166514327725 1.0913787242038728 0.9387741942374345 1.0278226954347653 0.8930334447938072 0.9154175663676464 1.0 15.375407999278883 -5.514022014406756 24.98923098420039 1.0426799595283447 0.8120394463074327 0.3286698262623836 0.13614053053527755 503.1304702544351 1419578.5131993773 0.040108845358883184 0.07439298950531763 3.061808226560722e-06 5.514022014406756 -0.23064051322091195 SNS(ph)VGIQDAFNDGSDSTFQKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSVGIQDAFNDGSDSTFQKR 21 1 O14497-2;O14497;H0Y488;A0A1B0GTU5;O14497-3;A0A087WUV6 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 S(0.128)NS(0.82)VGIQDAFNDGS(0.049)DS(0.002)T(0.002)FQKR 47.646 0.027431 7771700.0 12792.0 9992.0 7284.3 14410.0 19088.0 15362.0 17425.0 18315.0 14959.0 11425.0 True False 14957.432946483435 10983.939725172513 7457.985337861587 13602.654417850337 15347.843424354507 14556.38967674458 15774.377853924787 17834.250656346558 15177.747075352378 13496.262059749755 1.1082648573556797 0.8138505073882787 0.5525963637075281 1.0078830981222482 1.1371921615338791 1.0785497208265147 1.1687960550921068 1.3214214852521349 1.124588942342588 1.0 13.720272271671591 -5.994259182342532 24.821948291652788 1.1457040028781724 0.816538702122716 0.48072473308300856 0.14575474668460547 116.66290499832853 504414.2873416575 0.042353272799214234 0.0626082092721556 1.0133064746910786e-06 5.994259182342532 -0.32916530075545647 SNS(ph)VGIQDAFNDGSDSTFQKR ddPTM_PC-9_Lapatinib_30min_R1 2 SNSVGIQDAFNDGSDSTFQKR 21 1 O14497-2;O14497;H0Y488;A0A1B0GTU5;O14497-3;A0A087WUV6 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 S(0.165)NS(0.835)VGIQDAFNDGSDSTFQKR;S(0.204)NS(0.796)VGIQDAFNDGSDSTFQKR 124.08 1.2211e-06 44611000.0 104427.0 45752.0 62730.0 46957.0 49198.0 50500.0 45317.0 36160.0 59271.0 44799.0 True False 102937.8518304337 45646.06405499448 57572.58154480256 50410.37442396005 46304.270366989535 48340.23272124974 47663.29252221605 37840.12560857004 52595.27582870015 52542.44745908471 1.9591369798788372 0.8687464376405285 1.0957346741343723 0.959421893378969 0.8812735722493151 0.9200224781857131 0.9071387959103332 0.7201820135622059 1.0010054417365422 1.0 15.681195783196602 -4.75960918232074 24.999788136756763 0.9232608641572723 1.9591382784079145 0.9146591654649221 0.09446387832640313 12.600895792810451 172075.3945425104 0.023919302374007648 0.1501303391721488 1.7393653638594406e-05 4.75960918232074 1.0358774142506424 SNS(ph)VSLVPPGSSHTLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSVSLVPPGSSHTLPR 17 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 S(0.246)NS(0.661)VS(0.094)LVPPGSSHTLPR 76.678 0.0046298 3877000.0 20533.0 20151.0 37032.0 36316.0 45232.0 43719.0 31407.0 21941.0 26625.0 23678.0 True False 24008.83135476425 22151.458106680482 37914.98332464205 34281.33225806056 36369.11430062884 41426.298677099076 28431.90159301094 21365.071998411127 27014.340255448686 27970.63396505514 0.8583584978717131 0.7919540949395428 1.3555282076198485 1.2256187078523009 1.3002606357105193 1.4810639876398457 1.0164911395477156 0.7638393904515496 0.9658107960369725 1.0 14.771625332965842 -7.517893355154329 24.76995680414176 0.8969280525737129 1.1753862165968851 0.24424814402512518 0.20606187842969478 293.6565100937494 1459060.560692814 0.10361806923581256 0.06196323944570952 3.0346362744475345e-08 7.517893355154329 0.27845816402317225 SNS(ph)WQGNLGGNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNSWQGNLGGNK 12 0 Q9P0K1-5;Q9P0K1;H7C3I4;H7C0Q9;Q9P0K1-4;Q9P0K1-3;Q9P0K1-2 Q9P0K1-5 ADAM22 Disintegrin and metalloproteinase domain-containing protein 22 1 S(0.002)NS(0.998)WQGNLGGNK;S(0.006)NS(0.994)WQGNLGGNK 126.32 0.00026707 9636200.0 44616.0 45288.0 36896.0 40199.0 63406.0 43467.0 40805.0 41499.0 38415.0 39455.0 True False 52168.60759383246 49783.893342034935 37775.74056885919 37946.78035691642 50982.04946377943 41187.51400071976 36939.6549973831 40409.69522182506 38976.746700960095 46607.87917439183 1.1193087631950418 1.0681432887293472 0.8105011692875879 0.8141709305186717 1.0938504468959176 0.8837028144234844 0.7925624519229181 0.8670142460382044 0.8362694761356022 1.0 15.508286246122934 -5.148349365840397 5.258160828698832 0.8841678052253549 1.1056690186264084 0.4648664324604864 0.08903298486669597 0.1924763210401027 7.519340054627417 0.023522496111931135 0.0661835743763255 7.106416118623107e-06 5.148349365840397 0.22150121340105355 SNS(ph)WQGNLGGNK ddPTM_PC-9_Lapatinib_30min_R1 2 SNSWQGNLGGNK 12 0 Q9P0K1-5;Q9P0K1;H7C3I4;H7C0Q9;Q9P0K1-4;Q9P0K1-3;Q9P0K1-2 Q9P0K1-5 ADAM22 Disintegrin and metalloproteinase domain-containing protein 22 1 S(0.004)NS(0.996)WQGNLGGNK;SNS(1)WQGNLGGNK 155.43 0.00031862 10991500.0 85384.0 86606.0 44567.0 31639.0 38055.0 36975.0 33509.0 27137.0 52935.0 18956.6 True False 84166.40850249193 86405.46912805678 40902.87329359499 33965.83760460998 35816.67971900864 35393.665442934835 35243.93205920378 28397.8840884891 46972.90286973802 22233.22305191826 3.7856143621619514 3.8863222361546814 1.8397185688318785 1.527706420490368 1.6109531054211421 1.5919268816889374 1.5851922133333236 1.2772724864125788 2.1127347465569213 1.0 14.440429484188144 -5.296850608414553 4.238106030200012 1.5598942855149394 3.8707220624702203 0.9187330623184502 0.27067948002165015 0.04489326059990723 1.8598450001744689 0.06644978510540202 0.15896149567477852 5.048349242683102e-06 5.296850608414553 2.310827776955281 SNS(ph)WVNTGGPK ddPTM_PC-9_AZD4547_30min_R2 2 SNSWVNTGGPK 11 0 Q96N67-2;Q96N67-6;Q96N67;A0A1B0GWE0;A0A0U1RRC1 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 S(0.001)NS(0.963)WVNT(0.035)GGPK;S(0.058)NS(0.842)WVNT(0.1)GGPK 112.72 0.0016522000000000002 22010200.0 49879.0 52518.0 70983.0 78726.0 65538.0 62664.0 55671.0 72456.0 61091.0 60767.0 True False 65739.48445234893 69493.41645453508 70041.71904053171 60576.9370045753 56439.17996822644 58745.61017388832 60625.611150982666 61259.59007324217 64320.1455402516 58639.565826035316 1.1210772714002826 1.1850943211397513 1.1944447073213826 1.033038634431359 0.9624760888520779 1.0018084094989312 1.0338686908228363 1.0446801440341429 1.0968728133333854 1.0 15.839586801183783 -5.777667981974047 13.383034213495595 1.0233622625482353 1.1686947314335392 0.7522192968973249 0.03738871002738455 0.5316286258248034 437.8719442873697 0.011219236928408413 0.016939505840165753 1.6685223099839265e-06 5.777667981974047 0.14533246888530393 SNS(ph)WVNTGGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SNSWVNTGGPK 11 0 Q96N67-2;Q96N67-6;Q96N67;A0A1B0GWE0;A0A0U1RRC1 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 S(0.001)NS(0.998)WVNT(0.001)GGPK;S(0.056)NS(0.944)WVNTGGPK;SNS(0.953)WVNT(0.047)GGPK;S(0.001)NS(0.999)WVNTGGPK 184.31 0.00011479999999999999 28153100.0 204317.0 185267.0 179643.0 222218.0 218329.0 178148.0 203063.0 170879.0 185169.0 152183.0 True False 238903.83265530405 203659.0833730524 183926.37041987095 209767.84590047647 175548.99973784035 168805.6052683694 183827.40259119277 166393.60731126636 187876.7463196688 179772.57322003462 1.3289225846642083 1.1328707139535774 1.023105844931931 1.1668512173084868 0.9765060186515504 0.9389953219491269 1.0225553280933193 0.9255783812339776 1.0450801418396285 1.0 17.455813409095356 -1.522878745300776 0.5641237734170093 0.9849887244543153 17.48651274931137 0.7426666432994034 0.05897530982076756 71.4516418054086 0.6253298451327629 0.02847773012561706 1436.234366186693 0.029999999998588166 1.522878745300776 16.501524024857055 SNS(ph)WVNTGGPK ddPTM_PC-9_Lapatinib_30min_R1 1 SNSWVNTGGPK 11 0 Q96N67-2;Q96N67-6;Q96N67;A0A1B0GWE0;A0A0U1RRC1 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 S(0.006)NS(0.994)WVNTGGPK 125.97 0.00043404 6404000.0 37395.0 37106.0 30243.0 27926.0 28991.0 26580.0 28998.0 27055.0 27901.0 25927.0 True False 36861.74044259686 37020.083336785836 27756.53728135601 29979.77119840508 27285.806378499004 25443.2353610063 30499.374551696284 28312.07406913337 24758.4955694448 30408.447404444058 1.2122204054788304 1.2174276063622873 0.9127903477669668 0.9859027262938677 0.8973100801756589 0.8367160290231683 1.0029901936801593 0.9310595076615351 0.8141979509886604 1.0 14.892184536625457 -5.260735844215181 24.91840720659882 0.9213171030848366 1.2148240369417436 0.7894926276313874 0.06035077942894584 23.491220009007556 831990.2400264407 0.01547140095281073 0.036283404709144755 5.486105509848762e-06 5.260735844215181 0.29350693385690696 SNSFS(ph)DER ddPTM_PC-9_AZD4547_30min_R2 1 SNSFSDER 8 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 SNS(0.012)FS(0.988)DER 126.66 0.0035431999999999994 670090000.0 1008600.0 1283200.0 1071300.0 803730.0 1038600.0 1344000.0 1217800.0 1339100.0 1206700.0 1037000.0 True False 1329313.8198167405 1697969.3056563323 1057093.8620250158 618442.4660047158 894408.317540968 1259959.4675364778 1326181.8408088007 1132172.8644567528 1270483.6984731248 1000694.9456382357 1.3283906605213383 1.696790128757351 1.0563597494247454 0.6180129805794891 0.8937871840359113 1.2590844722743006 1.3252608565570119 1.1313866122654008 1.269601394521704 1.0 19.93257081573708 -5.276125528473604 24.27896137960162 1.067428963274308 1.512590376593503 0.4098994519198489 0.21279753389257625 504.9359417585235 834754.5169428639 0.06182993948566739 0.12966678758191402 5.2951037209703816e-06 5.276125528473604 0.445161413319195 SNSFS(ph)DER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSFSDER 8 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(0.001)NS(0.045)FS(0.953)DER 106.16 0.0038305999999999995 16907000.0 95148.0 135080.0 107680.0 97534.0 110150.0 66824.0 85841.0 55303.0 49435.0 66137.0 True False 111254.6771413388 148489.84968738054 110247.499578674 92069.48618949452 88566.89821839123 63319.63180307117 77709.51904497879 53851.35484837203 50157.89335316831 78127.11455979625 1.4240213243276465 1.9006186331600752 1.4111298004522328 1.1784575266635142 1.1336256140703196 0.8104693506197281 0.9946549220821685 0.6892786857903955 0.6420036582149581 1.0 16.25353571219422 -6.03908657893926 0.9415189083619165 0.794686814360298 1.7010921602840088 0.789802000312479 0.16720468943194158 0.25416408512504113 0.46059054919777465 0.07295899787860134 0.15362733277518828 9.139310262456843e-07 6.03908657893926 0.9064053459237108 SNSFS(ph)DER ddPTM_PC-9_Lapatinib_30min_R1 5 SNSFSDER 8 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(0.002)NS(0.094)FS(0.904)DER;S(0.001)NS(0.25)FS(0.749)DER;S(0.007)NS(0.419)FS(0.574)DER;S(0.005)NS(0.167)FS(0.828)DER;SNS(0.128)FS(0.871)DER 136.49 0.0034379 1660881800.0 2377580.0 3360488.0 2802921.0 2449486.0 3114287.0 2372087.0 2116819.0 2388857.0 2188441.0 1885932.0 True False 2343675.273205227 3352706.9965037648 2572475.6549679535 2629629.371685762 2931110.7615838163 2270638.3686148706 2226417.530145086 2499852.0171712376 1941955.7292746252 2211912.833353567 1.0595694540330913 1.5157500539569615 1.163009507507456 1.1888485531768802 1.3251475001118582 1.0265496607170852 1.0065575354384684 1.1301765510267034 0.8779531001365686 1.0 21.076863102561184 -6.773348157529426 24.694486157147914 1.0162777020415734 1.2569212873507623 0.48269730460335614 0.12514784167501272 166.11287262448423 344455.43979309796 0.041944422596679444 0.037284629145415055 1.6852015211458823e-07 6.773348157529426 0.24064358530918883 SNSGLAT(ph)YSPPMGPVSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSGLATYSPPMGPVSER 18 0 H0Y465;P21359-2;P21359-6;P21359;P21359-4;J3KSB5 H0Y465;J3KSB5 NF1 Neurofibromin;Neurofibromin truncated 1 SNS(0.001)GLAT(0.692)Y(0.087)S(0.22)PPMGPVSER 84.895 0.0072557 8356100.0 15906.0 16116.0 18502.0 23605.0 24877.0 19374.0 16324.0 18499.0 19907.0 18321.0 True False 18598.571642179915 17715.889973066485 18943.157849225747 22282.488378442544 20002.530431038722 18357.99333402222 14777.6725444745 18013.420851310682 20198.102214656054 21642.452271043807 0.8593560197918788 0.8185712853237613 0.8752777925526701 1.0295731786482931 0.9242266163063604 0.8482399824249132 0.6828095245124355 0.8323188438036417 0.9332631053866202 1.0 14.401576357403206 -6.8506029388390575 6.691382793546618 0.8369589107335512 0.9022851045530705 0.022739029355268503 0.09271033247256728 0.5720822377524005 35.7296005922725 0.0343985819834798 0.03039314868823104 1.410577853999803e-07 6.8506029388390575 0.06532619381951932 SNSGLATYS(ph)PPMGPVSER ddPTM_PC-9_AZD4547_30min_R2 4 SNSGLATYSPPMGPVSER 18 0 H0Y465;P21359-2;P21359-6;P21359;P21359-4;J3KSB5 H0Y465;J3KSB5 NF1 Neurofibromin;Neurofibromin truncated 1 SNSGLAT(0.128)Y(0.017)S(0.854)PPMGPVSER;SNS(0.001)GLAT(0.154)Y(0.069)S(0.771)PPMGPVS(0.005)ER;SNSGLAT(0.058)Y(0.001)S(0.941)PPMGPVSER;SNS(0.001)GLAT(0.023)Y(0.401)S(0.575)PPMGPVSER 118.72 8.5055e-05 41214400.0 80913.0 79582.0 107005.0 140301.0 107790.0 104977.0 97675.0 108639.0 84864.0 95007.0 True False 106641.65090504845 105305.32518916932 105586.04378417492 107956.77207884198 92825.21909083505 98412.77159492318 106367.88577845259 91851.33882586595 89349.73778671023 91680.83384788028 1.1631836931369062 1.1486078471307888 1.151669758581893 1.1775282526113064 1.0124822735017176 1.0734279725052758 1.1601976259830002 1.0018597668763418 0.974573790798654 1.0 16.484332545183655 -7.037296713222216 0.44010386301403787 0.9807255186451048 1.1780513685489447 0.5819309034768851 0.05030285487530797 0.9068309001558186 0.3847866878596638 0.05408786719309683 0.06636717144701507 9.177053990964515e-08 7.037296713222216 0.19732584990383983 SNSGLATYS(ph)PPMGPVSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SNSGLATYSPPMGPVSER 18 0 H0Y465;P21359-2;P21359-6;P21359;P21359-4;J3KSB5 H0Y465;J3KSB5 NF1 Neurofibromin;Neurofibromin truncated 1 SNSGLAT(0.088)YS(0.912)PPMGPVSER;SNSGLAT(0.231)Y(0.006)S(0.763)PPMGPVSER;SNS(0.001)GLAT(0.148)Y(0.367)S(0.483)PPMGPVSER 162.81 1.0309e-06 27555600.0 97962.0 106280.0 114209.0 112478.0 135156.0 106672.0 107960.0 107119.0 105743.0 90268.0 True False 114545.03176230524 116830.77601994952 116932.17570004439 106176.22231859602 108673.1520254643 101077.93253467641 97733.2472372868 104307.23975196235 107289.29132889809 106632.87383890514 1.0741999876637793 1.0956356310573678 1.0965865543181257 0.9957175352790453 1.0191336696940334 0.9479059214645118 0.9165395596946643 0.978190270943497 1.0061558641942319 1.0 16.70229274942875 -5.945107884053783 1.7143798441700593 0.9695484825233337 1.0926476255395856 0.7284900307907436 0.029872373969211937 0.18729236582326733 1.1160048324941205 0.010330282925768552 0.01808554641889562 1.1347289001397457e-06 5.945107884053783 0.12309914301625191 SNSGLATYS(ph)PPMGPVSER ddPTM_PC-9_Lapatinib_30min_R1 3 SNSGLATYSPPMGPVSER 18 0 H0Y465;P21359-2;P21359-6;P21359;P21359-4;J3KSB5 H0Y465;J3KSB5 NF1 Neurofibromin;Neurofibromin truncated 1 SNSGLAT(0.009)Y(0.403)S(0.588)PPMGPVSER;SNSGLAT(0.016)Y(0.053)S(0.931)PPMGPVSER;SNS(0.006)GLAT(0.031)Y(0.402)S(0.561)PPMGPVSER 123.55 4.0598e-05 25401200.0 107832.0 87234.0 93210.0 86276.0 90643.0 89577.0 82246.0 85672.0 102982.0 68869.0 True False 106294.29590603306 87032.01503264102 85546.63360100484 92621.02484829904 85311.55695099453 85746.00052418576 86504.29544723126 89652.63388101273 91383.08271146416 80772.9148878259 1.315964591022253 1.077490086293252 1.0591004883234496 1.1466841945338646 1.0561901482628393 1.061568728122122 1.070956713241869 1.1099343635860934 1.1313579909598808 1.0 16.301583983073883 -4.760673276775597 24.999653427367527 1.0826338226212748 1.315964861184003 0.7598006933661253 0.03988709345898831 8.816437325259121 287515.1290006046 0.009566214132102525 0.055840372412333666 1.7351088431785397e-05 4.760673276775597 0.23333103856272808 SNSGLGGEVS(ph)GVMSKPNVDPQPWFQDGPK ddPTM_PC-9_AZD4547_30min_R2 1 SNSGLGGEVSGVMSKPNVDPQPWFQDGPK 29 1 C9JRJ5;Q9UGP4 C9JRJ5 LIMD1 LIM domain-containing protein 1 1 S(0.084)NS(0.371)GLGGEVS(0.408)GVMS(0.137)KPNVDPQPWFQDGPK 79.408 4.4277e-06 8385500.0 36883.0 31624.0 34421.0 71042.0 47998.0 47945.0 61786.0 74458.0 70001.0 65904.0 True False 48611.02678594178 41845.839558974345 33964.55504971812 54664.364487958694 41334.30620578801 44946.99157071162 67284.83430465798 62952.226974625424 73701.10995012616 63596.721019616445 0.7643637282957981 0.6579873755765957 0.5340614186577596 0.859546901342562 0.6499439836377479 0.7067501413610254 1.0579921924575943 0.9898659233580261 1.1588822311671227 1.0 15.956664763130023 -7.252620931227455 6.727604312050904 1.0516482553501052 0.6910825988424711 0.7932196422460124 0.08910067245762061 0.0641146613020427 16.68328076114686 0.03504973339802191 0.025689023441288594 5.5895786159938665e-08 7.252620931227455 -0.36056565650763406 SNSGLGGEVS(ph)GVMSKPNVDPQPWFQDGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSGLGGEVSGVMSKPNVDPQPWFQDGPK 29 1 C9JRJ5;Q9UGP4 C9JRJ5 LIMD1 LIM domain-containing protein 1 1 S(0.004)NS(0.055)GLGGEVS(0.672)GVMS(0.27)KPNVDPQPWFQDGPK 74.471 9.1521e-06 7053800.0 54720.0 40672.0 34185.0 47151.0 61719.0 64920.0 68201.0 91285.0 79490.0 59635.0 True False 63983.01523073591 44709.64736811614 35000.10004733447 44509.282335604534 49625.6050035486 61515.48091487162 61740.50754751926 88888.8654744525 80652.39086969437 70446.35342959974 0.9082516285910677 0.6346623379561659 0.49683338233130364 0.6318181164633978 0.7044453344649235 0.8732244881397141 0.876418785952056 1.2617951270292962 1.144876731629466 1.0 16.10423740865083 -7.25550297527874 1.4265206874881398 1.145557614299087 0.6586325240900611 0.7008288794433499 0.12513918241059538 0.22581181620000185 0.8971584593331853 0.07663418452816954 0.045337036230091964 5.5526081310772265e-08 7.25550297527874 -0.48692509020902597 SNSGLGGEVSGVMS(ph)KPNVDPQPWFQDGPK ddPTM_PC-9_Lapatinib_30min_R1 1 SNSGLGGEVSGVMSKPNVDPQPWFQDGPK 29 1 C9JRJ5;Q9UGP4 C9JRJ5 LIMD1 LIM domain-containing protein 1 1 S(0.138)NS(0.372)GLGGEVS(0.093)GVMS(0.397)KPNVDPQPWFQDGPK 43.732 0.017025 4809800.0 10310.0 8141.3 9462.5 7365.0 13409.0 10953.0 14345.0 9645.8 13036.0 13130.0 True False 10162.97750937756 8122.449320049977 8684.529776306294 7906.64666891977 12620.308983108309 10484.565722690066 15087.71390937594 10093.979081724146 11567.748404834323 15399.503005374738 0.6599549028192973 0.5274487960562804 0.5639487049208807 0.5134351846394127 0.8195270314050762 0.6808379282779932 0.9797533013961569 0.6554743408408144 0.7511767360801803 1.0 13.910596170518243 -6.2658051274844695 24.726471681606327 0.7988186880046564 0.5632685863263408 0.5424769215771581 0.11112697667610817 255.39360692960366 1446481.5204104136 0.032677622668880725 0.03835674347747463 5.422441464905795e-07 6.2658051274844695 -0.23555010167831558 SNSISQIPS(ph)LEEMQQLR ddPTM_PC-9_AZD4547_30min_R2 2 SNSISQIPSLEEMQQLR 17 0 A0A1B0GV57;Q9NYJ8 A0A1B0GV57 TAB2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 1 S(0.005)NS(0.041)IS(0.118)QIPS(0.836)LEEMQQLR;S(0.01)NS(0.046)IS(0.286)QIPS(0.658)LEEMQQLR 61.419 0.028386 11990100.0 27611.0 28848.0 33466.0 61611.0 66434.0 66933.0 38674.0 71237.0 48766.0 56517.0 True False 36390.72365552255 38172.551846613074 33022.21897370405 47407.53583046113 57210.785834312264 62747.668929032014 42115.91107853469 60228.9585134088 51343.67120223786 54538.35703243596 0.6672500903149623 0.6999211916836889 0.605486134356129 0.8692512647982067 1.0490009040845678 1.1505236377346988 0.7722255192521993 1.1043412708158484 0.9414231376955837 1.0 15.73498361928082 -5.948779178445503 3.812906873228057 1.0021664234923706 0.6633023800106354 0.7098813230648935 0.09853669093230713 0.11944627553386901 3.6215884460802585 0.028380153738566793 0.0427113596544623 1.125176936481698e-06 5.948779178445503 -0.33886404348173527 SNSLASKSMES(ph)FLK ddPTM_PC-9_AZD4547_30min_R2 1 SNSLASKSMESFLK 14 1 H0YB35;E7ERK1;O43374-2;O43374 H0YB35 RASA4 Ras GTPase-activating protein 4 1 SNSLASKS(0.006)MES(0.994)FLK 54.523999999999994 0.036858999999999996 8106100.0 40685.0 51983.0 67050.0 30811.0 52817.0 35233.0 64979.0 58324.0 59675.0 37515.0 True False 53621.98369942906 68785.4881670302 66160.87319030822 23707.99997520473 45484.27123778292 33029.87494026247 70762.00511899739 49311.36595218851 62829.29867107297 36201.6112686773 1.481204339261672 1.9000670344898551 1.827567085323425 0.6548879772022079 1.25641565786154 0.9123868740295792 1.9546645201458965 1.362131800880757 1.7355387362394759 1.0 15.143766290051254 -1.5228787739278846 0.02648746057610392 1.958425406939195e-09 3.3764864235189687 0.06074310823152862 0.41504210823068705 6853.223345723097 13.999555931515602 600.4773964274885 1311.1114491792734 0.02999999802109762 1.5228787739278846 3.3764864215605432 SNSLPHS(ph)AVSNAGSK ddPTM_PC-9_AZD4547_30min_R2 1 SNSLPHSAVSNAGSK 15 0 A0A088AWN2;Q8TBZ3-4;Q8TBZ3-5;Q8TBZ3-6;Q8TBZ3;Q8TBZ3-2;Q8TBZ3-7 A0A088AWN2 WDR20 WD repeat-containing protein 20 1 SNS(0.149)LPHS(0.851)AVSNAGSK 177.66 4.3753999999999995e-05 9004200.0 8509.4 8870.0 18598.0 26891.0 23993.0 20454.0 15590.0 26887.0 18164.0 18628.0 True False 11215.212193484618 11737.054037696118 18351.37836828268 20691.695411808454 20661.98609932647 19175.008146570788 16977.479798168162 22732.23195179503 19124.11195745906 17975.83938992193 0.623904784094387 0.6529349635976633 1.0208913180750432 1.1510836831023956 1.1494309473476112 1.066710028424106 0.944461030714733 1.2645991910975656 1.0638786619433696 1.0 14.133771519082094 -5.294539977217716 3.485996164065229 1.097257096535194 0.623682174688264 0.8227302118311319 0.08301278143451957 0.08520451765724182 2.1627417730857843 0.0221232564122487 0.05735295844193854 5.075280184445954e-06 5.294539977217716 -0.47357492184692995 SNSLPHS(ph)AVSNAGSK ddPTM_PC-9_Lapatinib_30min_R1 2 SNSLPHSAVSNAGSK 15 0 A0A088AWN2;Q8TBZ3-4;Q8TBZ3-5;Q8TBZ3-6;Q8TBZ3;Q8TBZ3-2;Q8TBZ3-7 A0A088AWN2 WDR20 WD repeat-containing protein 20 1 SNS(0.003)LPHS(0.988)AVS(0.009)NAGSK;SNS(0.297)LPHS(0.703)AVSNAGSK 189.45 2.0410999999999997e-07 55800000.0 83360.0 60155.0 101048.0 61632.0 90541.0 96541.0 83004.0 81775.0 110942.0 69823.0 True False 82171.27111364825 60015.71479341218 92740.22349656 66164.62287832498 85215.55639045489 92412.16647806266 87301.5409783089 85574.56503431452 98446.54368894824 81891.8125167006 1.0034125340294633 0.7328658744874268 1.1324724736999445 0.8079516235500552 1.0405870107353707 1.1284664930235437 1.0660594544845992 1.0449709489195014 1.2021536789025344 1.0 16.321431599034618 -6.477070169062988 8.488124142779347 1.0892485770995406 0.9211923516587882 0.3404589362597008 0.11155393948786624 0.3974465771412057 69.4996791931659 0.03259780780971555 0.0366682809609251 3.3337254533003166e-07 6.477070169062988 -0.16805622544075238 SNSLS(ph)EQLAINTSPDAVK ddPTM_PC-9_AZD4547_30min_R2 1 SNSLSEQLAINTSPDAVK 18 0 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 S(0.003)NS(0.018)LS(0.896)EQLAINT(0.065)S(0.018)PDAVK 167.05 1.1911e-07 11347000.0 65266.0 55056.0 72326.0 101900.0 97429.0 69387.0 70597.0 88604.0 70469.0 86416.0 True False 86019.23038286666 72851.77532124003 71366.90998303109 78408.52933930609 83902.66509695663 65048.21992109646 76879.99623548926 74912.28771736688 74193.84747468516 83390.6021429834 1.0315218762346403 0.8736209290865502 0.8558147818703092 0.9402561838426955 1.0061405355137647 0.7800425737370659 0.9219263833071871 0.898330097064422 0.8897147348507055 1.0 16.347597185213758 SNSLSEQLAINTS(ph)PDAVK ddPTM_PC-9_AZD4547_30min_R2 3 SNSLSEQLAINTSPDAVK 18 0 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 SNSLSEQLAINT(0.144)S(0.856)PDAVK;SNSLSEQLAINT(0.363)S(0.637)PDAVK;SNSLSEQLAINT(0.035)S(0.965)PDAVK 205.0 4.0788e-20 46776000.0 160102.0 150642.0 182684.0 225027.0 198260.0 188122.0 183836.0 200746.0 171087.0 180403.0 True False 211011.10567152474 199334.08053513168 180261.49079639497 173150.50178249326 170735.02121670736 176358.7016011137 200197.04786247865 169725.31838416477 180130.30953896677 174087.14588039918 1.2121004374239839 1.1450246916683762 1.035466977672422 0.994619682612584 0.9807445595897426 1.0130483828040646 1.1499817913036348 0.9749445746027047 1.034713439800543 1.0 17.40945015669506 -5.121456887298112 2.4922215527596734 1.0224945762570021 1.2094970235771947 0.6513635202861237 0.046845158151452425 0.20298951641602647 2.276020134477123 0.013105387553755043 0.057740357613000635 7.560371089201289e-06 5.121456887298112 0.18700244732019256 SNSLSEQLAINTS(ph)PDAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SNSLSEQLAINTSPDAVK 18 0 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 SNSLSEQLAINT(0.012)S(0.988)PDAVK;SNSLSEQLAINT(0.052)S(0.948)PDAVK;SNSLSEQLAINT(0.228)S(0.772)PDAVK;SNSLSEQLAINT(0.003)S(0.997)PDAVK 255.93 3.3093999999999996e-65 39025200.0 303025.0 270225.0 275054.0 308848.0 356466.0 317847.0 322799.0 293821.0 280828.0 259258.0 True False 354321.1474834385 297051.1521451903 281612.3305081032 291544.24785872624 286619.0462125918 301178.5437823355 292221.1418576222 286108.510079083 284934.57822562027 306259.4231148016 1.1569314141580582 0.9699331015648143 0.9195221738615389 0.9519519265516302 0.9358701302887011 0.9834098840754313 0.954162124664105 0.9342031248189056 0.9303699958933584 1.0 18.224394708664178 -4.76457257157802 4.404395223966162 0.9492439650304489 1.1747335065963411 0.8738438375487285 0.02329979217799725 0.0637942082903339 2.647571810196043 0.00562207783396909 0.04587700258550319 1.7195999682327716e-05 4.76457257157802 0.22548954156589218 SNSLSEQLAINTS(ph)PDAVK ddPTM_PC-9_Lapatinib_30min_R1 4 SNSLSEQLAINTSPDAVK 18 0 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 SNSLSEQLAINT(0.098)S(0.902)PDAVK;SNSLSEQLAINT(0.085)S(0.915)PDAVK;SNSLSEQLAINT(0.023)S(0.977)PDAVK;SNSLSEQLAINT(0.079)S(0.921)PDAVK 351.47 7.560899999999997e-224 60843000.0 330421.0 306246.0 366521.0 320397.0 370439.0 341463.0 319174.0 313122.0 357989.0 276078.0 True False 325709.135948209 305536.90620269836 336387.05819197535 343960.06419306056 348650.5063310959 326859.42347913067 335699.26798962365 327670.79122805985 317668.50902870746 323797.71444918774 1.0059031346230245 0.943604270717127 1.0388802736430778 1.0622683510233264 1.0767540682743397 1.009455622733938 1.0367561381978303 1.0119614086389108 0.9810708811490326 1.0 18.30473327674048 -5.276465077564092 24.93114158184097 1.0303084239670834 0.9747537012820702 0.3156179320475402 0.030575559299697776 772.9545144644488 1282511.358759918 0.008343409303898337 0.017475795723403284 5.290965411467912e-06 5.276465077564092 -0.05555472268501327 SNSLVS(ph)TFTMEK ddPTM_PC-9_AZD4547_30min_R2 2 SNSLVSTFTMEK 12 0 Q9HB21 Q9HB21 PLEKHA1 Pleckstrin homology domain-containing family A member 1 1 SNSLVS(0.761)T(0.231)FT(0.008)MEK;S(0.002)NS(0.067)LVS(0.924)T(0.007)FTMEK 157.09 0.00040405 25832000.0 91723.0 83397.0 104798.0 107108.0 123168.0 121247.0 103994.0 139513.0 110967.0 106142.0 True False 120889.00604308036 110353.44933277834 103408.31004620333 82415.9054021041 106068.24923443688 113665.40592291337 113249.26453692775 117954.47153980682 116832.48907637961 102426.00088711029 1.1802570147820106 1.077396836516202 1.0095904277291436 0.804638516473366 1.035559802352734 1.1097319522236417 1.1056691031191035 1.1516067260090666 1.1406526474185745 1.0 16.644222465061375 -6.707077246154527 4.982947830380548 1.1115321290700813 1.010366237181628 0.1443099891434071 0.09530335900668241 0.3616065288620134 18.666707270192546 0.0347025780863512 0.03398536492671461 1.9630110931583633e-07 6.707077246154527 -0.10116589188845326 SNSLVS(ph)TFTMEK ddPTM_PC-9_Lapatinib_30min_R1 2 SNSLVSTFTMEK 12 0 Q9HB21 Q9HB21 PLEKHA1 Pleckstrin homology domain-containing family A member 1 1 SNS(0.002)LVS(0.968)T(0.03)FTMEK;SNS(0.024)LVS(0.939)T(0.036)FTMEK 186.29 0.000384 19221900.0 76404.0 99872.0 103755.0 97632.0 98529.0 87601.0 74516.0 87813.0 97884.0 104158.0 True False 75314.46494922243 99640.75252011731 95224.66440588207 104812.18297080444 92733.71793546723 83854.5094379049 78374.07387041186 91893.11255711711 86859.27315578418 122161.5715181889 0.6165151938800059 0.8156472717386547 0.7794977031030078 0.8579799823154595 0.7591071134973072 0.6864229757016479 0.6415607862309022 0.7522260185023484 0.7110196117839849 1.0 16.898431001007353 -10.092768364084783 8.769734944031836 0.9999999999718473 0.739775641823089 0.55494063039369 0.07095635440054167 0.0 0.0 0.07228517415675381 0.017531729764346905 8.076656930983058e-11 10.092768364084783 -0.26022435814875833 SNSNS(ph)SSVITTEDNK ddPTM_PC-9_AZD4547_30min_R2 1 SNSNSSSVITTEDNK 15 0 C9JYJ6;Q4L180-6;Q4L180-5;Q4L180-3;Q4L180-7;Q4L180-2;Q4L180;H7C4M0 C9JYJ6 FILIP1L Filamin A-interacting protein 1-like 1 SNS(0.138)NS(0.756)S(0.053)S(0.053)VITTEDNK 206.81 6.2963e-13 12206000.0 61168.0 67206.0 82033.0 117060.0 83930.0 83879.0 107550.0 132620.0 134710.0 101950.0 True False 80618.15162656203 88929.02521504014 80945.18882059 90073.62555897141 72277.7682372555 78634.03287015793 117121.74164804298 112126.62630442415 141830.4955840843 98380.76153116503 0.8194503719207727 0.903926985631934 0.8227745705642684 0.9155613776219644 0.7346738032146597 0.7992826203652456 1.1904943591124897 1.1397210649655798 1.4416486859491862 1.0 16.58608860205309 -7.26650002602628 23.13341452045009 1.2046095333785707 0.8347248024340038 0.7126577326774388 0.11199479416325053 78.95899285450807 360935.8021453337 0.043981080551817466 0.030754355404182636 5.4137721543918076e-08 7.26650002602628 -0.36988473094456686 SNSNS(ph)SSVITTEDNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSNSSSVITTEDNK 15 0 C9JYJ6;Q4L180-6;Q4L180-5;Q4L180-3;Q4L180-7;Q4L180-2;Q4L180;H7C4M0 C9JYJ6 FILIP1L Filamin A-interacting protein 1-like 1 SNS(0.453)NS(0.53)S(0.014)S(0.003)VITTEDNK 190.46 1.4746e-07 8514600.0 32812.0 36885.0 29415.0 41180.0 37902.0 33322.0 39456.0 38106.0 32357.0 33137.0 True False 38366.42353345956 40546.69903552725 30116.365157008713 38872.81810736131 30475.375181783573 31574.535659971556 35718.44204329735 37105.75787664441 32830.15991157009 39144.47578765233 0.9801235745648126 1.0358217403518593 0.7693643752028114 0.993060127263814 0.7785357848985852 0.8066153658885216 0.9124772097360496 0.9479181194795562 0.8386920312757383 1.0 15.256521103002092 -5.236263120321951 24.965388935679513 0.8778069789986729 1.0079726849719088 0.286918922305731 0.08005995669779789 908.8876083041116 901271.9309258079 0.019532941096659363 0.05162994797857034 5.804126639406179e-06 5.236263120321951 0.13016570597323596 SNSPGTAS(ph)SGSSR ddPTM_PC-9_AZD4547_30min_R2 1 SNSPGTASSGSSR 13 0 H0YAP0;Q96GY0 H0YAP0 ZC2HC1A Zinc finger C2HC domain-containing protein 1A 1 SNS(0.01)PGT(0.179)AS(0.608)S(0.179)GS(0.016)S(0.009)R 90.476 0.023748 0.0 3044.5 3278.7 3814.7 4770.9 4239.6 3541.9 3300.1 3622.8 3375.0 4801.2 True False 4012.5876704660623 4338.475656526978 3764.1145855192963 3671.042714670222 3651.0047208229284 3320.424433085904 3593.8025068591883 3062.9795036621063 3553.39560980094 4633.111449371545 0.8660675907138704 0.9364064957072137 0.8124377379330853 0.7923493217863727 0.788024367796757 0.7166726873225338 0.7756779749700748 0.6611063724956545 0.7669566442833871 1.0 12.177765671441161 -5.506469927821737 2.418072976510128 0.7674298218168873 0.9018542548308734 0.197953033069178 0.08491785565593879 0.37034786827106675 4.266038116393552 0.0228277451382506 0.054519485530909136 3.115516618556884e-06 5.506469927821737 0.1344244330139861 SNSPLPSIQLQPQS(ph)PSASK ddPTM_PC-9_AZD4547_30min_R2 2 SNSPLPSIQLQPQSPSASK 19 0 Q08174-2;Q08174 Q08174-2 PCDH1 Protocadherin-1 1 SNSPLPS(0.026)IQLQPQS(0.919)PS(0.053)AS(0.002)K;SNSPLPSIQLQPQS(0.999)PS(0.001)ASK 224.36 4.2840999999999994e-35 19330800.0 73237.0 159392.0 128037.0 123702.0 115117.0 95334.0 132075.0 138919.0 105866.0 95740.0 True False 96524.84257576716 210912.34691955592 126339.14572211045 95184.4150768484 99134.99161406117 89372.7499093174 143829.41913682254 117452.26059104451 111461.86063027747 92388.17174098811 1.0447748965784958 2.282893393657063 1.3674818252308802 1.0302662481913767 1.0730268793713973 0.9673613864757006 1.5567947327721874 1.2712911012063755 1.2064516326046888 1.0 16.495420537868895 -5.512950171896727 24.736748197394324 1.1762229598661385 1.7041725371794043 0.2800443452483773 0.32111371160083185 445.7571632119591 1110588.7592236458 0.08162451115618694 0.15312753104690027 3.0693741280659986e-06 5.512950171896727 0.5279495773132659 SNSPLPSIQLQPQS(ph)PSASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNSPLPSIQLQPQSPSASK 19 0 Q08174-2;Q08174 Q08174-2 PCDH1 Protocadherin-1 1 SNSPLPSIQLQPQS(0.995)PS(0.005)ASK;SNSPLPSIQLQPQS(0.979)PS(0.008)AS(0.013)K 170.04 4.7917e-08 12851800.0 85862.0 104868.0 81901.0 69023.0 156841.0 63819.0 76887.0 64270.0 72667.0 59309.0 True False 100396.74074819869 115278.6019915324 83853.83045127202 65155.86508558525 126109.13194253882 60472.21929307138 69603.70674632516 62582.98059969385 73729.61740254234 70061.25221021428 1.4329852462094843 1.6453973966329687 1.1968645693010738 0.9299843070187964 1.7999839849301649 0.8631335779102031 0.9934693507544472 0.893260948461464 1.0523594009042454 1.0 16.096329153320625 -6.798092161176018 24.9999969910823 0.9558372553780264 1.3771058587582006 0.48531939557192993 0.22616961096690966 161.54881924651744 110187.55451113664 0.08077836332120167 0.07124179473086445 1.5918708819570837e-07 6.798092161176018 0.42126860338017413 SNSPLPSIQLQPQS(ph)PSASK ddPTM_PC-9_Lapatinib_30min_R1 2 SNSPLPSIQLQPQSPSASK 19 0 Q08174-2;Q08174 Q08174-2 PCDH1 Protocadherin-1 1 SNSPLPSIQLQPQS(0.962)PS(0.034)AS(0.004)K;SNSPLPSIQLQPQS(0.803)PS(0.197)ASK 202.86 1.6447000000000001e-16 11429900.0 102061.0 121850.0 52161.0 32242.0 46839.0 35884.0 29096.0 30669.0 60755.0 18579.5 True False 100605.59142430467 121567.86381144164 47872.52392728274 34613.18423615904 44084.02210901707 34349.3249696896 30602.448512178624 32093.993702689004 53912.13212148736 21790.941819372405 4.61685374860049 5.578825588133431 2.196900176417501 1.5884207540487079 2.023043449633088 1.5763120866649576 1.4043655738171301 1.4728135189713123 2.47406158799244 1.0 14.411440931614758 -5.332497683162794 4.6799280759154955 1.6907711106113301 5.101272886610747 0.9053160733602842 0.4390181159231024 0.05066547643817726 2.11075271079367 0.11090830989382428 0.2469879325522444 4.6505285708435456e-06 5.332497683162794 3.410501775999417 SNSPLPSIQLQPQS(ph)PSASKK ddPTM_PC-9_AZD4547_30min_R2 1 SNSPLPSIQLQPQSPSASKK 20 1 Q08174-2;Q08174 Q08174-2 PCDH1 Protocadherin-1 1 SNSPLPSIQLQPQS(0.887)PS(0.097)AS(0.016)KK 79.332 0.00074768 38445000.0 50176.0 113720.0 102500.0 96104.0 85872.0 70752.0 99341.0 96896.0 87245.0 69863.0 True False 66130.92427436532 150477.76608419418 101140.78302768971 73948.70759199875 73950.15505861543 66327.8662553132 108182.15655098295 81922.94964857113 91856.5925858023 67417.11763464224 0.9809218577506195 2.2320409320921675 1.5002240762621775 1.096883257346503 1.0969047276594956 0.9838431036872254 1.6046689675649026 1.2151654138128722 1.3625114185926253 1.0 16.040827326908648 -5.581909777422047 6.003191727547425 1.2109583651913276 1.6682336028621945 0.21263935008354617 0.33039948796936397 0.24767030705391768 17.874426494486904 0.08623948126396164 0.15227146442848533 2.618726979576664e-06 5.581909777422047 0.45727523767086686 SNSPLPSIQLQPQS(ph)PSASKK ddPTM_PC-9_Lapatinib_30min_R1 1 SNSPLPSIQLQPQSPSASKK 20 1 Q08174-2;Q08174 Q08174-2 PCDH1 Protocadherin-1 1 SNSPLPSIQLQPQS(0.499)PS(0.499)AS(0.003)KK 115.38 8.9491e-06 22487000.0 66683.0 64108.0 24927.0 14011.0 25824.0 15726.0 13950.0 15010.0 33999.0 7829.4 True False 65732.08819183547 63959.56186478382 22877.598281002603 15041.415679325843 24305.083091937446 15053.435639096491 14672.262742125777 15707.419396699019 30169.674594658038 9182.701357980268 7.1582517637591145 6.965222908964526 2.491379975144321 1.6380164281672989 2.6468336652171534 1.6393254067893905 1.597815519653678 1.7105445101999768 3.285490120882451 1.0 13.164702911336366 -5.277784404760709 4.216788605019949 1.972439508024044 7.174530090432267 0.9201143500229108 0.5983203668907439 0.04570451789568618 2.0022168194319376 0.15246305080716313 0.3786141825248485 5.274916572123169e-06 5.277784404760709 5.202090582408223 SNSPLPVPPS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 SNSPLPVPPSK 11 0 Q13247-3;Q13247 Q13247-3 SRSF6 Serine/arginine-rich splicing factor 6 1 S(0.008)NS(0.325)PLPVPPS(0.667)K 77.597 0.019326 17014000.0 51734.0 55036.0 69839.0 83234.0 71223.0 72859.0 71740.0 74607.0 69954.0 75110.0 True False 68184.33586595202 72825.31071236113 68912.88922800808 64045.68725248095 61334.915848469565 68303.11521223247 78124.72102120475 63078.20244830488 73651.62562607854 72480.42176170467 0.9407276366316275 1.004758373948076 0.9507793629371303 0.8836274085579309 0.8462273584737351 0.9423664149857459 1.077873432884496 0.8702791859529785 1.016158899685 1.0 16.145303729963253 -7.0157773418953475 24.90727907831409 0.984532399721219 0.9253059659196948 0.20082295783281234 0.06180272066076427 1314.8310151740757 2075687.0199862164 0.024043633841010367 0.019222012574457013 9.643232950794568e-08 7.0157773418953475 -0.05922643380152415 SNSPLPVPPS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSPLPVPPSK 11 0 Q13247-3;Q13247 Q13247-3 SRSF6 Serine/arginine-rich splicing factor 6 1 S(0.002)NS(0.085)PLPVPPS(0.913)K 86.67 0.010791 15993000.0 91469.0 122960.0 98721.0 98047.0 122120.0 107780.0 123990.0 109730.0 101560.0 88319.0 True False 106952.89510490121 135166.65618566974 101074.88304147721 92553.74446266297 98191.46264575524 102127.82706415375 112244.76959013677 106849.70376854554 103045.1228673566 104330.53556718092 1.0251351104780986 1.2955617974244242 0.9687948259059083 0.8871203810035596 0.9411574675807871 0.9788872117731171 1.075857312338435 1.0241460296131852 0.9876794200965582 1.0 16.670801943549527 -5.290783452370182 24.761118507237665 0.9820748506215647 1.1603484801648742 0.46312363728276473 0.07639389246985481 463.8782068878181 391428.9963300395 0.020112381068840075 0.04187697784102525 5.119370336197183e-06 5.290783452370182 0.1782736295433095 SNSQS(ph)DSHDEEVSPTPPNPVVK ddPTM_PC-9_AZD4547_30min_R2 1 SNSQSDSHDEEVSPTPPNPVVK 22 0 C9J4C2;C9IZL8;C9JR00;C9JSK5;P31321 C9J4C2 PRKAR1B cAMP-dependent protein kinase type I-beta regulatory subunit 1 S(0.023)NS(0.062)QS(0.458)DS(0.458)HDEEVSPTPPNPVVK 80.98100000000001 0.00025996 18545000.0 43774.0 32261.0 85672.0 121930.0 98272.0 93228.0 63853.0 122510.0 84077.0 102960.0 True False 57693.2214442376 42688.737351760414 84535.9333029097 93820.92229972134 84628.62909819577 87398.43842223997 69535.7933003483 103578.89449973615 88521.13857340267 99355.40173858489 0.5806752369240565 0.42965693464839716 0.8508438577434687 0.9442961394950082 0.8517768296168045 0.8796546226263066 0.6998692782029579 1.0425089394964528 0.89095446271066 1.0 16.600310785369828 -5.312494951519969 6.136608126073939 0.8908049201898709 0.5055133982150507 0.7334228935146194 0.09406231447922662 0.09331470063087625 8.395179373013136 0.02419511448671031 0.05209178824039825 4.869731859794778e-06 5.312494951519969 -0.3852915219748202 SNSQSDS(ph)HDEEVSPTPPNPVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSQSDSHDEEVSPTPPNPVVK 22 0 C9J4C2;C9IZL8;C9JR00;C9JSK5;P31321 C9J4C2 PRKAR1B cAMP-dependent protein kinase type I-beta regulatory subunit 1 S(0.156)NS(0.156)QS(0.156)DS(0.531)HDEEVSPTPPNPVVK 95.209 9.4851e-05 7811200.0 43720.0 48842.0 56276.0 59370.0 66968.0 52163.0 56856.0 57395.0 55382.0 37588.0 True False 51120.93249063913 53690.71097446715 57617.83326791847 56043.69138013703 53846.10113381044 49427.480452286625 51470.188078206425 55888.44206502924 56191.85697754965 44402.40685355571 1.1513099427074278 1.2091846991886126 1.297628605087755 1.262176880748281 1.2126842878450517 1.1131711984736365 1.1591756331579295 1.2586804640873592 1.2655137628659843 1.0 15.438350260214401 -6.533380401671811 24.73991058247449 1.1740741458654562 1.2339109357675642 0.14370190118594395 0.07876902401338537 446.23131577944184 1051228.377110689 0.026370276786134798 0.026398432827382322 2.9283271786812705e-07 6.533380401671811 0.059836789902107945 SNSQSDS(ph)HDEEVSPTPPNPVVK ddPTM_PC-9_Lapatinib_30min_R1 1 SNSQSDSHDEEVSPTPPNPVVK 22 0 C9J4C2;C9IZL8;C9JR00;C9JSK5;P31321 C9J4C2 PRKAR1B cAMP-dependent protein kinase type I-beta regulatory subunit 1 S(0.191)NS(0.191)QS(0.13)DS(0.489)HDEEVSPTPPNPVVK 83.411 0.00015587 18751000.0 32331.0 29144.0 56610.0 39070.0 55117.0 55354.0 34290.0 45699.0 64080.0 28754.0 True False 31869.95401122075 29076.518858602027 51955.74432091936 41943.338133699275 51875.126424191265 52986.63845647635 36065.36841774144 47822.342372401654 56862.63560768512 33724.090587703366 0.9450204128807945 0.8621883748943564 1.5406121682007254 1.2437203614022092 1.5382216546146454 1.5711806466264382 1.06942449119419 1.4180469076855955 1.6861132388375994 1.0 15.041491919170724 -5.253832609137259 24.76923488062746 1.3943768755574537 0.9036043218265456 0.4515309777834552 0.21124895585697656 427.86937812774283 1393222.0012683794 0.05214338221332534 0.1324075513502525 5.574005473776887e-06 5.253832609137259 -0.4907725537309081 SNSQSDSHDEEVS(ph)PTPPNPVVK ddPTM_PC-9_AZD4547_30min_R2 4 SNSQSDSHDEEVSPTPPNPVVK 22 0 C9J4C2;C9IZL8;C9JR00;C9JSK5;P31321 C9J4C2 PRKAR1B cAMP-dependent protein kinase type I-beta regulatory subunit 1 SNSQSDSHDEEVS(1)PTPPNPVVK;SNSQSDSHDEEVS(0.996)PT(0.004)PPNPVVK;SNSQSDSHDEEVS(0.997)PT(0.002)PPNPVVK;SNSQSDSHDEEVS(0.997)PT(0.003)PPNPVVK 149.44 1.0073999999999999e-06 115511000.0 73467.0 62012.0 263724.0 460031.0 348000.0 290741.0 171207.0 366133.0 204638.0 289228.0 True False 96827.97779146976 82056.16628924588 260226.84744579962 353977.96035809926 299686.2069172518 272560.9193087965 186444.0913280933 309555.55774934235 215454.74690324278 279102.21575415146 0.346926582183644 0.2940004115249499 0.9323711269817424 1.2682735584940767 1.0737507264407813 0.9765630794879935 0.6680136552277445 1.1091117887147692 0.7719564186227283 1.0 18.090434052244007 -5.2798095817082595 6.152972722963528 0.983713638635433 0.3172253489046441 0.7307107975641751 0.15897749220210003 0.0759053306315073 12.067700164420355 0.04317585204407817 0.09772513026660652 5.25037614800326e-06 5.2798095817082595 -0.6664882897307889 SNSQSDSHDEEVS(ph)PTPPNPVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SNSQSDSHDEEVSPTPPNPVVK 22 0 C9J4C2;C9IZL8;C9JR00;C9JSK5;P31321 C9J4C2 PRKAR1B cAMP-dependent protein kinase type I-beta regulatory subunit 1 SNSQSDSHDEEVS(0.991)PT(0.009)PPNPVVK;SNSQSDSHDEEVS(0.986)PT(0.014)PPNPVVK;SNSQSDSHDEEVS(0.997)PT(0.003)PPNPVVK;SNSQSDSHDEEVS(0.983)PT(0.017)PPNPVVK;SNSQSDSHDEEVS(0.993)PT(0.007)PPNPVVK;SNSQSDSHDEEVS(0.999)PT(0.001)PPNPVVK 132.81 4.0203e-07 83672600.0 89679.1 130090.0 269895.0 293773.0 368526.0 307270.0 270172.0 229373.0 260693.0 164546.0 True False 104860.00038703743 143004.47546514144 276330.32038248685 277313.85123491654 296315.9757860261 291156.2202820798 244579.35228410727 223352.20179078245 264505.1419422979 194376.88725458056 0.5394674329242628 0.735707199991554 1.4216212857682493 1.4266812024400373 1.5244403795700936 1.4978952713690945 1.2582738397481137 1.1490676949582599 1.360784945567466 1.0 17.568497157240728 -5.173438644827318 4.039968865398418 1.3495128503138445 0.5853660123659913 0.7618010102403936 0.15567969682610022 0.10384964373850328 3.0673965595124844 0.04165609633485582 0.12451913901451765 6.707510407015833e-06 5.173438644827318 -0.7641468379478532 SNSQSDSHDEEVS(ph)PTPPNPVVK ddPTM_PC-9_Lapatinib_30min_R1 4 SNSQSDSHDEEVSPTPPNPVVK 22 0 C9J4C2;C9IZL8;C9JR00;C9JSK5;P31321 C9J4C2 PRKAR1B cAMP-dependent protein kinase type I-beta regulatory subunit 1 SNSQSDSHDEEVS(0.997)PT(0.003)PPNPVVK;SNSQSDSHDEEVS(0.999)PT(0.001)PPNPVVK;SNSQSDSHDEEVS(0.993)PT(0.007)PPNPVVK;SNSQSDSHDEEVS(0.917)PT(0.083)PPNPVVK 134.91 4.4693000000000005e-07 72951000.0 154717.0 134495.0 375152.0 172241.0 289287.0 311447.0 180195.0 222571.0 363300.0 153517.0 True False 152510.70720837716 134183.58509084804 344308.45068859844 184908.17771913196 272271.70742012514 298127.13782841736 189524.61539909348 232912.4611953831 322381.32828139816 180052.2089014553 0.8470360243780629 0.7452482027826067 1.9122700731599607 1.0269697819721522 1.5121819892203747 1.6557816182726526 1.0526092212666078 1.2935829147359077 1.7904880492626518 1.0 17.458055773224253 -5.22699143874234 24.91020276290727 1.4025992075273188 0.7961417477726792 0.39000570811247426 0.30480707623713105 575.4067176180216 416089.79825904744 0.07349375615449615 0.1944247623603023 5.929370130465176e-06 5.22699143874234 -0.6064574597546396 SNSS(ph)EALLVDR ddPTM_PC-9_AZD4547_30min_R2 1 SNSSEALLVDR 11 0 Q96HB5-2;Q96HB5;Q96HB5-5;Q96HB5-3;Q96HB5-4 Q96HB5-2 CCDC120 Coiled-coil domain-containing protein 120 1 S(0.03)NS(0.32)S(0.649)EALLVDR 145.52 0.00020569999999999999 12496000.0 7276.2 13005.0 13444.0 19571.0 15686.0 13099.0 12452.0 15691.0 17533.0 13548.0 True False 9589.880245638089 17208.61192336394 13265.723775846453 15059.208318935824 13508.269660068978 12279.917459271084 13560.203877279657 13266.316493309614 18459.758585671083 13073.688643690262 0.7335252128913473 1.3162782434526854 1.0146886725995936 1.1518714212460484 1.033240887726698 0.9392848333739174 1.0372133104014376 1.0147340092661852 1.411977834930335 1.0 13.674378623755922 SNSS(ph)EALLVDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSSEALLVDR 11 0 Q96HB5-2;Q96HB5;Q96HB5-5;Q96HB5-3;Q96HB5-4 Q96HB5-2 CCDC120 Coiled-coil domain-containing protein 120 1 SNS(0.324)S(0.676)EALLVDR 115.83 0.0013210999999999997 10148000.0 10292.0 10553.0 10410.0 19515.0 18163.0 14073.0 15422.0 16179.0 14791.0 11174.0 True False 12034.23232373417 11600.632097652671 10658.213880144853 18421.63781848364 14604.090534186449 13334.98710589939 13961.116514388976 15754.318393067488 15007.290393177154 13199.757746664678 0.9117009989653019 0.8788518941253998 0.8074552643087693 1.3956042354745812 1.1063908000793892 1.0102448364454932 1.0576797530937019 1.1935308734774543 1.1369368045386443 1.0 13.688223831792827 -5.723485721975955 24.9999910649468 1.1278757416416156 0.8672873766893867 0.5524372809810741 0.10832177438009367 126.61333694657733 83399.00882384946 0.029773173242356704 0.051567264769836654 1.890228374003949e-06 5.723485721975955 -0.2605883649522289 SNSS(ph)SEAVLGQEELSAQAK ddPTM_PC-9_AZD4547_30min_R2 3 SNSSSEAVLGQEELSAQAK 19 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 S(0.001)NS(0.011)S(0.855)S(0.13)EAVLGQEELS(0.004)AQAK;SNS(0.228)S(0.711)S(0.061)EAVLGQEELSAQAK;S(0.005)NS(0.119)S(0.866)S(0.01)EAVLGQEELSAQAK 324.71 5.106799999999999e-177 50688800.0 87963.0 77749.0 117714.0 158756.0 124471.0 117640.0 90055.0 138187.0 96934.0 105065.0 True False 115933.40425593907 102879.843785438 116153.03544703887 122157.2569557496 107190.3501758539 110283.95220311866 98069.72054034851 116833.3743713581 102057.73334531691 101386.706329297 1.1434773695024218 1.0147271522095944 1.1456436415813909 1.2048646353989574 1.0572426510010797 1.0877555470134717 0.9672838194568117 1.152353978162496 1.0066184911248666 1.0 16.629508975199315 -6.483779877563745 24.87783775420201 1.0503706022412966 1.1217885477174934 0.2719558642587012 0.06523522865635425 799.5130122940715 508714.69101560605 0.020121343312775188 0.022810592586078617 3.282616305730934e-07 6.483779877563745 0.07141794547619673 SNSS(ph)SEAVLGQEELSAQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNSSSEAVLGQEELSAQAK 19 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 S(0.001)NS(0.047)S(0.872)S(0.079)EAVLGQEELSAQAK;S(0.001)NS(0.051)S(0.868)S(0.081)EAVLGQEELSAQAK 226.72 3.0813000000000004e-35 17599500.0 38122.0 40310.0 45786.0 53431.0 67150.0 80005.0 91808.0 90274.0 83218.0 73310.0 True False 44575.30165617897 44311.710400490774 46877.71188437196 50437.434295639236 53992.43954030832 75809.39695924676 83111.28160763993 87904.40315320922 84434.90581701163 86600.52267835946 0.5147232404327955 0.5116794798695112 0.5413098031576453 0.5824148946879626 0.623465515801101 0.8753919100558815 0.9597087758502473 1.0150562656497175 0.9749930278205008 1.0 16.40208811192872 -6.786215863637579 1.5691410993103376 0.9980305877097094 0.5279538311734804 0.9901467520026647 0.02086664158399357 0.03361708698101001 0.17180202789888577 0.009443987640303209 0.008406669060308373 1.6360031531086402e-07 6.786215863637579 -0.47007675653622905 SNST(ph)ETLSPAK ddPTM_PC-9_AZD4547_30min_R2 1 SNSTETLSPAK 11 0 Q9P0K1-5;Q9P0K1 Q9P0K1-5 ADAM22 Disintegrin and metalloproteinase domain-containing protein 22 1 SNS(0.278)T(0.707)ET(0.002)LS(0.013)PAK 164.53 0.0041111 6249300.0 19261.0 34369.0 37829.0 34049.0 34498.0 24297.0 29030.0 36667.0 31373.0 22354.0 True False 25385.597346311988 45478.1071275736 37327.36274297047 26199.529101806038 29708.548178825695 22777.70474905791 31613.613761438224 31000.957673837493 33031.312730751095 21571.39326402806 1.1768176971973527 2.108260072538375 1.730410376654562 1.2145496946409924 1.3772197194312414 1.0559218160025605 1.4655341625131064 1.4371328404426222 1.531255414356259 1.0 14.396831740572123 -5.753806418788917 24.98997515454663 1.3158603897968937 1.7154725824071693 0.28753636094696833 0.2663687757808964 202.45968740753264 662836.3615363638 0.07023267508522094 0.11872430130334738 1.762761599762443e-06 5.753806418788917 0.3996121926102756 SNSTSSMSS(ph)GLPEQDR ddPTM_PC-9_Lapatinib_30min_R1 1 SNSTSSMSSGLPEQDR 16 0 P42684-2;P42684-6;P42684-3;P42684 P42684-2 ABL2 Abelson tyrosine-protein kinase 2 1 S(0.003)NS(0.264)T(0.063)S(0.063)S(0.14)MS(0.14)S(0.326)GLPEQDR 71.354 0.015991 2173800.0 14294.0 13662.0 14386.0 11615.0 12414.0 14063.0 12547.0 10307.0 12385.0 11172.0 True False 14090.164938801436 13630.366478390777 13203.238611565905 12469.20584650415 11683.832926863051 13461.55827245416 13196.622267057493 10785.900847553421 10990.07088016823 13103.065314245741 1.0753334888350525 1.0402425807625144 1.0076450277028883 0.9516251004982433 0.8916869943524062 1.027359472734877 1.007140081390729 0.8231585960139355 0.838740448635309 1.0 13.677616733017944 -4.492541204635754 0.4466717527819394 0.9112771134930117 1.2494553836058242 0.3814891653241428 0.06491963969685183 7.33525146954489 0.9393098452953988 0.04984496526622121 1.3875339787809806 3.2170572928916764e-05 4.492541204635754 0.33817827011281254 SNSVS(ph)LVPPGSSHTLPR ddPTM_PC-9_AZD4547_30min_R2 1 SNSVSLVPPGSSHTLPR 17 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 S(0.021)NS(0.287)VS(0.684)LVPPGS(0.002)S(0.006)HTLPR 195.17 4.146e-12 8955300.0 10684.0 10307.0 39455.0 96436.0 51452.0 44620.0 21495.0 54623.0 30858.0 36724.0 True False 14081.289758994719 13638.536185629539 38931.80092056095 74204.1701213477 44308.77792616785 41829.904346337535 23408.013358667395 46182.27046166922 32489.090882144435 35438.30393791565 0.39734660506506536 0.38485296050067425 1.0985796890496102 2.0938973335559727 1.2503075204669045 1.1803585301265922 0.6605286020368211 1.3031738353668372 0.9167789445866841 1.0 15.113021938326382 -5.290785477301252 5.165721145662288 1.2185388962384014 0.3839157826849526 0.45215442977882603 0.3510151105076015 0.15877435668103507 12.153116998526226 0.09824273516457047 0.2246368315364963 5.119346466799074e-06 5.290785477301252 -0.8346231135534488 SNSVS(ph)LVPPGSSHTLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSVSLVPPGSSHTLPR 17 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 S(0.025)NS(0.072)VS(0.684)LVPPGS(0.096)S(0.096)HT(0.026)LPR 98.40799999999999 0.0013587 5549600.0 8380.3 8783.2 22604.0 20755.0 30657.0 23521.0 14776.0 15096.0 13854.0 8124.7 True False 9798.919271530263 9655.138049853409 23142.965086147382 19592.164638617895 24649.980923115887 22287.51735364597 13376.310311023972 14699.745995534144 14056.588540807003 9597.643794910187 1.0209713426462874 1.005990455175437 2.4113173587897205 2.041351508482529 2.568336713661768 2.3221863438467536 1.3937077262773268 1.5315994539544902 1.4645874384566635 1.0 13.228464554805921 -7.304313688137574 21.207568622195193 1.3917716595534857 1.9153387603209973 0.210566553723466 0.5156506102366197 163.37959599247307 80812.70538465584 0.24084934094683833 0.1623829952759466 4.962337654870626e-08 7.304313688137574 0.5235671007675116 SNSVS(ph)LVPPGSSHTLPR ddPTM_PC-9_Lapatinib_30min_R1 2 SNSVSLVPPGSSHTLPR 17 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 S(0.008)NS(0.312)VS(0.679)LVPPGSSHTLPR;S(0.001)NS(0.075)VS(0.918)LVPPGS(0.003)S(0.003)HTLPR 159.54 2.71e-05 11174700.0 34965.0 24274.3 64198.0 24421.1 42992.0 56253.0 40908.0 42239.0 67397.0 26814.1 True False 34466.3926882043 24218.094349758558 58919.88825144642 26217.109160401444 40463.29508552408 53847.190322147704 43026.016075618754 44201.57814105064 59806.04013812663 31448.88145745761 1.095949715567106 0.7700780831432597 1.8735130001729996 0.8336420230355909 1.2866370188796918 1.7122132116205577 1.3681254811501669 1.4055055726177164 1.9016905329058869 1.0 14.940721085223931 -6.531424790748981 23.750010066171637 1.4963937740994406 1.155213665376866 0.16491378590344064 0.3540010705620778 186.55202288703353 518432.67591366515 0.11240099706125153 0.11261120028425228 2.94154305341977e-07 6.531424790748981 -0.34118010872257454 SNSVSLVPPGS(ph)SHTLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNSVSLVPPGSSHTLPR 17 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 SNS(0.005)VS(0.125)LVPPGS(0.386)S(0.386)HT(0.099)LPR 125.23 3.8905e-05 4703900.0 8669.1 9372.0 26578.0 17903.0 27412.0 21067.0 17782.0 12062.0 13811.0 11998.0 True False 10136.607407470257 10302.390222609769 27211.720317626296 16899.95295230913 22040.815378688483 19962.20943366607 16097.56022946861 11745.385280745419 14012.959747155002 14173.142423884257 0.7151983028399035 0.7268952723743476 1.9199496839719696 1.1923927980734683 1.5551114015157148 1.4084533151960859 1.135779190530208 0.8287072075810346 0.9886981537376412 1.0 13.790872043008902 -7.560266684327477 5.394186685278116 0.935678302142414 1.2709872949759755 0.14475352366998517 0.33922090470320715 0.37412264822358404 27.550685512810485 0.17187660220247356 0.09904956140014899 2.7525379515821725e-08 7.560266684327477 0.3353089928335615 SNT(ph)ENLSQHFR ddPTM_PC-9_AZD4547_30min_R2 1 SNTENLSQHFR 11 0 Q9UHB6;Q9UHB6-4;F8VRN8;F8VTU2;F8VVQ7 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 S(0.001)NT(0.999)ENLSQHFR 151.07 0.0007398 12971000.0 15332.0 14915.0 43411.0 72882.0 55913.0 41827.0 27654.0 49575.0 37279.0 40862.0 True False 20207.25707458881 19735.98207127821 42835.34177575651 56080.18091567525 48150.44507863298 39211.5510778633 30115.15242710341 41914.322870169155 39249.49183341314 39431.4338174248 0.5124656934402219 0.500513934204362 1.0863247320422704 1.4222201803601002 1.2211182910968672 0.9944236686756157 0.7637346530826756 1.062967252579265 0.9953858643625774 1.0 15.267058550651507 -5.261116400891869 24.776992888022477 1.075106723943729 0.5064897579721523 0.6620150456451857 0.16050250027354254 15.720119026985916 1205807.1970703553 0.047187273444184594 0.1101341656876268 5.481300337980135e-06 5.261116400891869 -0.5686169659715767 SNT(ph)ENLSQHFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNTENLSQHFR 11 0 Q9UHB6;Q9UHB6-4;F8VRN8;F8VTU2;F8VVQ7 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 S(0.196)NT(0.804)ENLSQHFR 116.58 0.0026156 7973700.0 18943.0 30340.0 50229.0 50029.0 56625.0 67456.0 39752.0 50766.0 52866.0 35271.0 True False 22149.675758695714 33351.95468992536 51426.649854543306 47226.037326206395 45529.73773596364 63918.48861049883 35986.40278044293 49433.44629102317 53639.06523735402 41665.353094917606 0.5316089775655246 0.8004721480205979 1.2342785080301262 1.1334606289936155 1.092748155337664 1.5340920900126895 0.8637008955249342 1.1864401143657444 1.2873781512221718 1.0 15.346560585883319 -5.040071527485861 2.7769969758020543 1.1721537605253116 0.534807037556873 0.601631264956479 0.16907276560550716 0.189520815681701 2.6796798422598997 0.04331474214581718 0.20912368486347213 9.118606452514835e-06 5.040071527485861 -0.6373467229684386 SNT(ph)LDIMDGR ddPTM_PC-9_AZD4547_30min_R2 1 SNTLDIMDGR 10 0 H0Y9X0;A0A286YEZ9;A0A2C9F2R7;O94915 H0Y9X0 FRYL Protein furry homolog-like 1 S(0.027)NT(0.973)LDIMDGR 118.73 0.0020753 1922200.0 8545.9 6746.2 9669.0 12891.0 10278.0 10232.0 10576.0 10789.0 10374.0 11135.0 True False 11263.318434237448 8926.777220868727 9540.782742387628 9919.179113964623 8851.077111193996 9592.191422494976 11517.243511573226 9121.807956555827 10922.348461059246 10745.167039230228 1.048221809220412 0.8307713773343287 0.8879138600223305 0.9231293545972853 0.8237263393746252 0.8926982137619845 1.0718533708712181 0.848921931436936 1.0164894059982628 1.0 13.391400289936918 SNT(ph)LDIMDGR ddPTM_PC-9_Lapatinib_30min_R1 4 SNTLDIMDGR 10 0 H0Y9X0;A0A286YEZ9;A0A2C9F2R7;O94915 H0Y9X0 FRYL Protein furry homolog-like 1 SNT(1)LDIMDGR;S(0.005)NT(0.995)LDIMDGR;S(0.005)NT(0.995)LDIMDGR;SNT(1)LDIMDGR 147.7 0.00036244 31469100.0 132878.0 130918.0 119365.0 116080.0 127580.0 131856.0 116746.0 114881.0 136498.0 96047.5 True False 130983.13535315923 130614.86741457817 109551.2704622245 124616.91043152848 120075.99523193075 126216.82625134868 122790.5366374347 120218.79065370926 121124.15785233765 112649.18239975083 1.1627526499779457 1.1594834923086585 0.9724994725080828 1.1062389249245375 1.0659286882866568 1.1204415652432456 1.0900259906165666 1.0671962999881939 1.075233350762478 1.0 16.78147731706381 -14.52283955141875 0.012916163716586736 2.539562084227252e-07 1.9462739234545192 0.28071612012824254 0.04937402465173232 11978.333576888263 11.699785972345099 1070.4903769575158 723.902523685823 3.0002707538214884e-15 14.52283955141875 1.9462736694983107 SNT(ph)LNEKPALPVIR ddPTM_PC-9_AZD4547_30min_R2 1 SNTLNEKPALPVIR 14 1 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9;A0A087WZS7 Q9UMZ2-4 SYNRG Synergin gamma 1 S(0.083)NT(0.917)LNEKPALPVIR 60.541000000000004 0.039951 23062000.0 60427.0 41479.0 70378.0 86935.0 81487.0 80469.0 66172.0 56804.0 53615.0 74247.0 True False 79641.52904031954 54886.2755839456 69444.74173583175 66893.47888236096 70173.93661800605 75437.26070922073 72061.17980785 48026.2470260633 56448.97944280813 71647.63512902803 1.1115723344796455 0.7660584398229278 0.9692537878015212 0.9336453151858333 0.9794313028145585 1.0528925424177376 1.0057719236381946 0.6703116849505821 0.7878694019858561 1.0 16.128631465838275 -7.74154418676871 24.993489562891753 0.7968178453528185 0.9675830347338785 0.2733452359480171 0.11346499756027732 266.41268473622415 334683.65559745615 0.05194631410046462 0.029940697743253135 1.8132421803447525e-08 7.74154418676871 0.17076518938106 SNT(ph)LNEKPALPVIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNTLNEKPALPVIR 14 1 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9;A0A087WZS7 Q9UMZ2-4 SYNRG Synergin gamma 1 S(0.163)NT(0.837)LNEKPALPVIR 69.069 0.022026 6199500.0 10114.0 11397.0 12543.0 22277.0 25975.0 34795.0 39091.0 36682.0 32714.0 31144.0 True False 11826.100439394415 12528.418839850998 12842.07268959239 21028.891913008465 20885.385213097685 32970.288946903245 35388.01748566849 35719.13636779166 33192.38036119244 36790.16066423163 0.32144737141341334 0.34053721466977604 0.3490626965942498 0.5715901081522949 0.5676894266298491 0.8961713771192588 0.9618880930866295 0.9708882952098317 0.9022080839528094 1.0 15.16703235618608 -6.464384849472652 1.04565288623578 0.9771692059797927 0.3230794317401715 0.9590410250557294 0.055039321993216164 0.0905780640905839 0.2112527306484188 0.02635060504970772 0.03245575509388934 3.4325363933635766e-07 6.464384849472652 -0.6540897742396212 down SNT(ph)LPSDVGR ddPTM_PC-9_AZD4547_30min_R2 2 SNTLPSDVGR 10 0 F5H4N6;Q9Y3R0-3;Q9Y3R0-2;Q9Y3R0;F5H4P8;H0YFK8 F5H4N6 GRIP1 Glutamate receptor-interacting protein 1 1 S(0.001)NT(0.998)LPSDVGR;S(0.009)NT(0.912)LPS(0.079)DVGR 144.51 0.00032674 60750000.0 289235.0 347355.0 373020.0 453682.0 448100.0 423575.0 376756.0 396978.0 400830.0 386211.0 True False 381205.71353826596 459630.71085275547 368073.51107306144 349092.6242170271 385889.0497690243 397088.78829000256 410286.5541269183 335634.17174693 422017.05548933655 372689.87044347863 1.0228496768228608 1.233279322311128 0.9876134026263607 0.9366839613902781 1.0354159862457206 1.0654670807593742 1.1008792743379419 0.900572294459051 1.132354509627969 1.0 18.507616082181983 -5.290186131982198 24.972965380244247 1.0184277859396764 1.1280645744385978 0.22015945463494568 0.08141268288872748 863.401769333124 750055.3821260099 0.020438147009836406 0.04255732601784952 5.126416265305516e-06 5.290186131982198 0.10963678849892133 SNT(ph)LPSDVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNTLPSDVGR 10 0 F5H4N6;Q9Y3R0-3;Q9Y3R0-2;Q9Y3R0;F5H4P8;H0YFK8 F5H4N6 GRIP1 Glutamate receptor-interacting protein 1 1 S(0.004)NT(0.613)LPS(0.383)DVGR 81.789 0.03864 23968000.0 94874.0 104780.0 111890.0 114290.0 153140.0 98987.0 106350.0 99790.0 96357.0 95664.0 True False 110934.29435308528 115181.8659331038 114557.88194518775 107886.70183317913 123133.31632468807 93795.94746334567 96275.75809267738 97170.61823624473 97766.03883546572 113007.12592419247 0.9816575144783551 1.0192442732360985 1.0137226392434364 0.9546893698150661 1.0896066537192395 0.8300002915414905 0.8519441345429948 0.8598627514996603 0.8651316280802435 1.0 16.78605422239901 -6.771692991107874 24.999999587745496 0.8707889446495776 1.0091343177830667 0.5895076940777855 0.05402226225840346 132.76846383295688 323709.53662610723 0.017769190102785708 0.015842556984514148 1.6916363506498926e-07 6.771692991107874 0.13834537313348916 SNT(ph)LPSDVGR ddPTM_PC-9_Lapatinib_30min_R1 1 SNTLPSDVGR 10 0 F5H4N6;Q9Y3R0-3;Q9Y3R0-2;Q9Y3R0;F5H4P8;H0YFK8 F5H4N6 GRIP1 Glutamate receptor-interacting protein 1 1 S(0.003)NT(0.769)LPS(0.228)DVGR 129.76 0.00057598 29632000.0 229100.0 226800.0 239360.0 239780.0 235670.0 227130.0 204480.0 230480.0 222150.0 194250.0 True False 225832.99198820585 226274.85853455015 219680.74475631915 257414.22108263153 221808.35394504693 217416.17936588993 215066.97387167567 241188.942208607 197129.1276567923 227825.85367814466 0.9912526973661463 0.9931921899180695 0.9642485311024783 1.1298727380005216 0.9735872832870022 0.9543086346690014 0.9439972259491946 1.0586548379594387 0.8652623241578262 1.0 17.79757194780779 -6.490756630422522 24.99675703194843 0.9665120133595104 1.0185374457800045 0.15738433297411958 0.06103175901384682 1311.9453389991913 1020929.2976494964 0.018478482011137734 0.020932843834245363 3.2303038095487803e-07 6.490756630422522 0.05202543242049407 SNT(ph)MPPNLGNAGLLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SNTMPPNLGNAGLLGR 16 0 M0R0S1;M0R2P6;Q8TBC3;M0QXA4;Q8TBC3-2 M0R0S1 SHKBP1 SH3KBP1-binding protein 1 1 S(0.055)NT(0.945)MPPNLGNAGLLGR;S(0.001)NT(0.999)MPPNLGNAGLLGR;S(0.013)NT(0.987)MPPNLGNAGLLGR 89.911 0.013905 15413300.0 62876.0 57204.0 55424.0 66103.0 74709.0 65379.0 55713.0 54256.0 57735.0 44390.0 True False 73519.66494239302 62882.83507193441 56745.51835669048 62399.46321881755 60070.30775304387 61950.410146848335 50435.46131280983 52831.83748898381 58579.26515111102 52437.555608953335 1.4020421830997796 1.1991946295299398 1.082154148829195 1.1899765825118533 1.145558885334222 1.1814130050003846 0.9618194579649387 1.0075190743628628 1.117124253234814 1.0 15.678312815051253 -1.5228787452803376 0.39274236029706155 1.0430347007380056 5.97457567773409 0.6661504737316267 0.07026860684137211 47.61044470486914 0.6386116600796861 0.055366698993997605 180.61256671994295 0.029999999999999995 1.5228787452803376 4.931540976996084 SNT(ph)MPPNLGNAGLLGR ddPTM_PC-9_Lapatinib_30min_R1 1 SNTMPPNLGNAGLLGR 16 0 M0R0S1;M0R2P6;Q8TBC3;M0QXA4;Q8TBC3-2 M0R0S1 SHKBP1 SH3KBP1-binding protein 1 1 S(0.021)NT(0.979)MPPNLGNAGLLGR 83.292 0.021543 10100000.0 34105.0 25777.0 31142.0 25749.0 29133.0 29220.0 25122.0 22965.0 31417.0 24488.0 True False 33618.65644590901 25717.31494023415 28581.62497159639 27642.66735614599 27419.454217681752 27970.328715146876 26422.694237109958 24032.037737854287 27878.48662432339 28720.718171791053 1.1705367618184637 0.8954272935101327 0.9951570431016841 0.9624643503272873 0.9546924994588966 0.9738728867378673 0.9199872398407443 0.8367491924856566 0.9706751223131012 1.0 14.809804204264985 -4.7541020874742665 24.998089253231342 0.9428125003368781 1.170537161810015 0.6713210782279693 0.04721711042543742 157.59909573514474 536893.1283970241 0.011953275021453361 0.12082146008428768 1.761561916018084e-05 4.7541020874742665 0.22772466147313697 SNT(ph)PESIAETPPAR ddPTM_PC-9_AZD4547_30min_R2 3 SNTPESIAETPPAR 14 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 S(0.362)NT(0.631)PES(0.007)IAETPPAR;S(0.412)NT(0.588)PESIAETPPAR;S(0.174)NT(0.821)PES(0.005)IAET(0.001)PPAR 137.39 0.00017244 45351000.0 100719.0 102146.0 111366.0 129379.0 126363.0 104378.0 99059.0 122134.0 108939.0 109067.0 True False 132745.54691465656 135162.69692610018 109889.21407474813 99552.67043562407 108819.6786341515 97851.22715961479 107875.05909728956 103260.99666011594 114697.29313662357 105248.59752741111 1.2612571571804945 1.2842232590405604 1.0440919561529398 0.945881206727685 1.0339299638250317 0.9297152594753604 1.0249548367539474 0.9811151795464303 1.0897750262824322 1.0 16.683441483465018 -5.314935064916791 4.211703175146969 0.9994339419057514 1.275699922831141 0.85858704118166 0.0434732022432981 0.06336071436748146 2.361763943994698 0.010974942561312586 0.025626391798379285 4.842447657489816e-06 5.314935064916791 0.27626598092538956 SNT(ph)PESIAETPPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNTPESIAETPPAR 14 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 S(0.432)NT(0.568)PESIAETPPAR;S(0.162)NT(0.696)PES(0.01)IAET(0.132)PPAR 180.56 0.00010740000000000001 37717000.0 242101.0 277542.0 230664.0 266631.0 270852.0 232876.0 251627.0 265764.0 216824.0 176171.0 True False 283083.91758728743 305094.53554882156 236163.90455809148 251692.52949936493 217780.49492735046 220663.57260523184 227791.0689382802 258787.97660023405 219994.64080929186 208109.40773113095 1.3602648754496507 1.4660295220434798 1.1348064805566398 1.2094240824736844 1.046471167746122 1.0603248311115294 1.0945736255834102 1.2435188751033197 1.0571105035939372 1.0 17.666982659021194 -5.28873069456389 8.407645557696485 1.113761412415449 1.41316498309444 0.7292929758870423 0.07478104854188804 0.12775660496169952 36.873468980628054 0.019428125650723105 0.0416115445016211 5.14362508224671e-06 5.28873069456389 0.29940357067899104 SNT(ph)PESIAETPPAR ddPTM_PC-9_Lapatinib_30min_R1 2 SNTPESIAETPPAR 14 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 S(0.02)NT(0.931)PES(0.042)IAET(0.007)PPAR;S(0.025)NT(0.882)PES(0.081)IAET(0.012)PPAR 142.57 2.6391e-05 50663000.0 144125.0 147261.0 137523.0 131176.0 140893.0 128966.0 110802.0 126980.0 120253.0 96154.0 True False 142069.75107071194 146920.02620218904 126216.38979413178 140823.12063030814 132605.95074629557 123450.4248144294 116538.78540165014 132879.95436328082 106708.84081977165 112774.09078284848 1.2597729681037602 1.302781739868691 1.1191966959606623 1.2487187407386802 1.1758547537451152 1.0946700962736085 1.0333826200031242 1.178284421899238 0.9462177001740963 1.0 16.783076129118655 -6.429141994495689 0.34599919737276275 0.98396640623979 1.3342367891748537 0.6582564766034269 0.06568541803992467 1.3992289198926995 0.3010455122014077 0.07306773952149156 0.18701660127379297 3.72269971046327e-07 6.429141994495689 0.35027038293506363 SNT(ph)PILVDGK ddPTM_PC-9_AZD4547_30min_R2 2 SNTPILVDGK 10 0 P06744-2;P06744;A0A2U3TZU2;K7EQ48;A0A0J9YXP8;A0A2R8Y6C7;A0A0J9YYH3;A0A0J9YX90;K7EPY4;K7ERC6;K7EP41 P06744-2 GPI Glucose-6-phosphate isomerase 1 S(0.059)NT(0.941)PILVDGK;S(0.036)NT(0.964)PILVDGK 133.04 0.00030923 15812800.0 168214.0 169962.0 159135.0 136409.0 152944.0 177185.0 211260.0 205586.0 193357.0 171707.0 True False 221702.55293144257 224898.89271194025 157024.76592303827 104962.01254804121 131710.36560560955 166105.59394006757 230061.73073515116 173817.4075963005 203577.45627386085 165695.59019354288 1.3380111846819822 1.3573016182823223 0.9476701566989408 0.6334629209228742 0.7948936085249073 1.0024744397002103 1.3884601905604401 1.0490164970188454 1.228623260498783 1.0 17.33817568176042 -5.2570363068627115 24.381980856990044 1.0000753855991475 1.3476564604346566 0.3269594099336094 0.19619238679055584 335.33404861351835 1856884.2404266545 0.0572561838106029 0.1407482738003617 5.533038512789408e-06 5.2570363068627115 0.34758107483550904 SNT(ph)PILVDGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNTPILVDGK 10 0 P06744-2;P06744;A0A2U3TZU2;K7EQ48;A0A0J9YXP8;A0A2R8Y6C7;A0A0J9YYH3;A0A0J9YX90;K7EPY4;K7ERC6;K7EP41 P06744-2 GPI Glucose-6-phosphate isomerase 1 S(0.006)NT(0.994)PILVDGK 113.54 0.0031601 7596800.0 83296.0 114390.0 82147.0 85976.0 97777.0 67122.0 89727.0 53851.0 55961.0 67839.0 True False 97396.36762900883 125745.88322282641 84105.69602423228 81159.04345795285 78618.29874806733 63602.00415847221 81227.4089927752 52437.46830985086 56779.3237571893 80137.6736867716 1.2153630514618512 1.569123203080743 1.049515067694256 1.0127451886758456 0.9810404411707415 0.7936592270829925 1.013598289741514 0.6543422824427054 0.708522236109805 1.0 16.2901930099911 -5.696417767259586 1.025175771781088 0.8250255297576801 1.424304359304082 0.6387873550631109 0.14970518527223864 0.389414872276335 0.753229579170852 0.056253959817691025 0.18480175689957032 2.011788089953582e-06 5.696417767259586 0.599278829546402 SNT(ph)PILVDGK ddPTM_PC-9_Lapatinib_30min_R1 3 SNTPILVDGK 10 0 P06744-2;P06744;A0A2U3TZU2;K7EQ48;A0A0J9YXP8;A0A2R8Y6C7;A0A0J9YYH3;A0A0J9YX90;K7EPY4;K7ERC6;K7EP41 P06744-2 GPI Glucose-6-phosphate isomerase 1 SNT(1)PILVDGK;S(0.019)NT(0.981)PILVDGK;S(0.004)NT(0.996)PILVDGK 108.32 0.004998600000000001 25548700.0 192140.0 374574.0 334810.0 311906.0 381362.0 380147.0 386532.0 378637.0 323745.0 311382.0 True False 189400.04836583912 373706.6969167574 307283.2142039743 334844.6077279144 358931.03694653965 363888.99897593906 406544.7356443989 396229.85730232636 287281.4289140137 365203.96380956506 0.518614437779217 1.02328214901749 0.8414016403288727 0.9168701353485816 0.9828234973202634 0.9963993686708403 1.1131991323522188 1.0849549746643488 0.7866328336562527 1.0 18.478342898404534 -4.757675973475694 24.998820861363058 0.9741356392576882 0.518613787542152 0.6691654956303206 0.09556676777353103 67.44556685184303 447949.50040307286 0.02454522081284475 0.17875402300218785 1.7471251945008468e-05 4.757675973475694 -0.45552185171553616 SNTACDGDKES(ph)EVEDVETDSGNSPEDLRK ddPTM_PC-9_Lapatinib_30min_R1 2 SNTACDGDKESEVEDVETDSGNSPEDLRK 29 2 Q7Z3K6-4;Q7Z3K6-3;Q7Z3K6;Q7Z3K6-2 Q7Z3K6-4 MIER3 Mesoderm induction early response protein 3 1 S(0.011)NT(0.046)ACDGDKES(0.928)EVEDVET(0.012)DS(0.002)GNS(0.001)PEDLRK;S(0.007)NT(0.106)ACDGDKES(0.881)EVEDVET(0.004)DSGNSPEDLRK 55.163000000000004 0.00079186 23167000.0 58599.0 67642.0 54913.0 67872.0 69853.0 56188.0 58659.0 61094.0 59186.0 62280.0 True False 57763.36751425949 67485.37910491222 50398.265110309934 72863.53329435481 65744.38387628192 53784.97022062535 61696.075999308676 63932.65027461222 52519.849423789805 73045.01501711631 0.7907913702355193 0.9238875382406133 0.6899617324809959 0.9975154810671341 0.9000529859686706 0.7363263626959644 0.8446308893885738 0.875250012059429 0.7190066209375556 1.0 16.15649819870439 -11.639494152767877 2.4946940180704975 1.3218982923382858 0.8352910001849216 0.22830020631162828 0.09298444571508317 25334625.976960834 7079313.081462252 46246707.562412806 0.0224229629989963 2.293537509854263e-12 11.639494152767877 -0.4866072921533642 SNTAGS(ph)QSQVETEA ddPTM_PC-9_AZD4547_30min_R2 1 SNTAGSQSQVETEA 14 0 Q02790 Q02790 FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed 1 S(0.007)NT(0.007)AGS(0.887)QS(0.099)QVETEA 72.815 0.021917 5334100.0 29579.0 32079.0 41908.0 49316.0 46936.0 42961.0 26103.0 46465.0 32019.0 39710.0 True False 38984.50671857963 42447.909410964385 41352.27253779923 37946.95812460475 40419.74657433364 40274.6418785972 28426.116431788567 39284.90190947877 33711.45897191596 38319.7649867833 1.0173472288263146 1.1077288554771905 1.079136903685653 0.9902711600056229 1.0548015257472125 1.051014845536974 0.7418134333963919 1.0251863998390478 0.8797407547656733 1.0 15.225801092673596 -7.091923197432937 24.99999617275351 0.9113016830536649 1.0515563967397201 0.4360274695262202 0.07707931809556316 55.494966036785506 15090.06186007203 0.02783958349107968 0.021564453221777444 8.092389959470132e-08 7.091923197432937 0.14025471368605524 SNTAGS(ph)QSQVETEA ddPTM_PC-9_Lapatinib_30min_R1 2 SNTAGSQSQVETEA 14 0 Q02790 Q02790 FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed 1 S(0.001)NT(0.003)AGS(0.931)QS(0.065)QVETEA;S(0.008)NT(0.036)AGS(0.835)QS(0.121)QVETEA 89.992 0.0051064 10121300.0 50481.0 42424.0 46749.0 45344.0 48261.0 44307.0 41773.0 45713.0 46541.0 39326.0 True False 49761.131682918385 42325.76983452278 42905.47767635858 48678.74902314973 45422.38286477664 42412.09289466162 43935.80154314121 47836.99286351112 41299.06248154299 46123.446701398854 1.078868455019629 0.917662769405286 0.9302313843570005 1.0554013740190273 0.9848002721661097 0.9195343350906888 0.9525697814298146 1.0371513033968534 0.8954027817762902 1.0 15.493212705921996 -4.744690049632843 24.919526690744203 0.9674359550338469 1.078868794144479 0.31005585407264613 0.05052324468352676 1266.3935186498925 1884025.659287562 0.012498866814977605 0.34626576551175925 1.800155204322256e-05 4.744690049632843 0.11143283911063206 SNTEPQS(ph)PPIASPK ddPTM_PC-9_AZD4547_30min_R2 2 SNTEPQSPPIASPK 14 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 SNT(0.001)EPQS(0.999)PPIASPK;S(0.001)NT(0.006)EPQS(0.993)PPIASPK 189.45 2.8605e-06 18233100.0 79786.0 75500.0 93130.0 122210.0 96108.0 93081.0 74560.0 97330.0 80613.0 81317.0 True False 105156.28834810501 99903.89851703012 91895.03534993889 94036.37262567806 82765.06314483692 87260.63035547848 81195.69555814084 82289.8849208991 84874.03860529866 78470.11658096839 1.3400806947903643 1.2731457893776104 1.1710832015282935 1.1983717716112712 1.0547335310689496 1.1120237124337609 1.0347339738479948 1.0486780000637483 1.0816096917317877 1.0 16.259855723125696 -2.631939878129841 0.31005008143467033 1.01632706661554 2.611536384626689 0.9109396042574404 0.031566621318061476 7.137448392208621 0.1898072575234374 0.03017378319663305 5.596635205777829 0.0023337811185933422 2.631939878129841 1.5952093180111488 SNTEPQS(ph)PPIASPK ddPTM_PC-9_Lapatinib_30min_R1 2 SNTEPQSPPIASPK 14 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 SNTEPQS(1)PPIASPK;S(0.004)NT(0.019)EPQS(0.977)PPIASPK 176.42 0.00010228 11705000.0 44931.0 35577.0 39019.0 32076.0 56187.0 74211.0 71103.0 63448.0 66231.0 59012.0 True False 44290.27570066374 35494.62364234438 35811.00843769567 34434.976042399256 52882.191127892205 71037.16852429032 74784.3654303491 66396.02570831178 58771.36733665091 69212.14557145265 0.6399205708041477 0.5128380770352038 0.5174093093346659 0.4975279375908028 0.7640594102562264 1.0263685360101078 1.0805092778570757 0.9593117676111689 0.8491481784216185 1.0 16.07873760842552 -6.516724565216672 3.171345278200978 0.9855453900065033 0.5398691638884299 0.9045343530641569 0.06741834108710326 0.07505581247711031 1.5583770773506682 0.024610594178689292 0.026294832862432952 3.042814203218941e-07 6.516724565216672 -0.44567622611807345 SNTEPQSPPIAS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 SNTEPQSPPIASPK 14 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 SNTEPQS(0.001)PPIAS(0.999)PK;SNTEPQSPPIAS(1)PK 125.41 3.5107e-05 29710000.0 84476.0 103229.0 91606.0 116990.0 102297.0 100339.0 101627.0 98127.0 105563.0 100858.0 True False 111337.6107900448 136595.75549688083 90391.24458570291 90019.7629774822 88094.82732475299 94064.78646811195 110671.60612241385 82963.72688413708 111142.84466886426 97326.99211878583 1.1439540909078878 1.403472485106374 0.9287376771634126 0.9249208366330145 0.90514281194712 0.9664820048410372 1.137111131384202 0.8524225919042208 1.1419529387409448 1.0 16.570552348949697 -5.2712570398693765 24.937216331523224 0.9770138980659374 1.2737132918901608 0.5461829197603332 0.1062463867546041 395.1341343009968 1003656.610441172 0.02637486477086471 0.0560200024785868 5.354796367794995e-06 5.2712570398693765 0.2966993938242234 SNTEPQSPPIAS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNTEPQSPPIASPK 14 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 SNTEPQS(0.001)PPIAS(0.999)PK;SNTEPQSPPIAS(1)PK 144.3 6.9379e-05 14945000.0 27936.0 30720.0 27045.0 43570.0 64969.0 74469.0 99682.0 88280.0 84920.0 85655.0 True False 32665.01303884939 33769.67857859282 27689.855368733657 41128.91415584586 52238.79083386881 70563.71454481792 90239.39932481674 85962.74354039169 86161.794347144 101183.57345539282 0.322829209557912 0.3337466490396321 0.2736595914053267 0.4064781737914969 0.5162773862389678 0.6973831041451231 0.8918384303218856 0.8495721252450993 0.8515393497653921 1.0 16.626615570615343 -6.7356503287655345 1.1514555917058613 0.9073510197042427 0.3074769329198293 0.9708162870580391 0.04444368545510162 0.07160770258443178 0.20138453753435925 0.022668646582312175 0.020970154998667768 1.8380176235432188e-07 6.7356503287655345 -0.5998740867844135 down SNTEPQSPPIAS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 SNTEPQSPPIASPK 14 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 SNTEPQSPPIAS(1)PK;SNTEPQS(0.02)PPIAS(0.98)PK 136.36 5.4241000000000005e-05 25505000.0 46320.0 48392.0 43765.0 56927.0 79315.0 105883.0 114131.0 113374.0 108999.0 99571.0 True False 45659.46830595234 48279.95129719564 40166.81063778548 61113.60148290507 74649.84763928974 101354.63091532838 120040.14473272812 118641.76993213534 96722.38480964537 116781.71467998247 0.3909813144212963 0.41342046937311583 0.3439477725417442 0.523314815597416 0.639225480152035 0.8678981225191889 1.0279018856819728 1.0159276240912372 0.8282322714193247 1.0 16.833454873606257 -6.542896603071558 1.4607053446230391 0.9740114901780511 0.38959178776324094 0.9444891608023029 0.061484472017630326 0.0846020147318581 0.3710660687857254 0.02586314908504018 0.028165213173179472 2.8648599552256125e-07 6.542896603071558 -0.5844197024148101 down SNTLPS(ph)DVGR ddPTM_PC-9_Lapatinib_30min_R1 1 SNTLPSDVGR 10 0 F5H4N6;Q9Y3R0-3;Q9Y3R0-2;Q9Y3R0;F5H4P8;H0YFK8 F5H4N6 GRIP1 Glutamate receptor-interacting protein 1 1 SNT(0.046)LPS(0.953)DVGR 126.83 0.00033306 30293000.0 240390.0 253690.0 245380.0 236640.0 269780.0 239070.0 208870.0 228010.0 233400.0 191870.0 True False 236961.99451787365 253102.59639166656 225205.80359419168 254043.29500789862 253912.07080788744 228845.53339938974 219684.2665912408 238604.17699142807 207112.03418904057 225034.4738492955 1.0530030819925216 1.1247281008205354 1.0007613488811982 1.1289083430747158 1.1283252137533877 1.016935447644553 0.9762249438206623 1.0603005526665223 0.9203569153041969 1.0 17.779786504508735 -6.914085431041203 6.038212067681232 0.9945507201534214 1.0864132551247143 0.4789865351326875 0.048694456823362396 0.19080751530588183 10.685900317162949 0.016823627870149745 0.01480556642671849 1.2187498323312304e-07 6.914085431041203 0.09186253497129293 SNTPESIAET(ph)PPAR ddPTM_PC-9_AZD4547_30min_R2 1 SNTPESIAETPPAR 14 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 SNTPESIAET(1)PPAR 106.35 0.0021612 18805000.0 10930.0 8554.3 15419.0 17981.0 14381.0 14796.0 10125.0 14333.0 11262.0 12705.0 True False 14405.512641876845 11319.310186546101 15214.53398540437 13835.75825368071 12384.446384129284 13870.803781004268 11026.105385275985 12118.164189574065 11857.286328171314 12260.201817101037 1.174981689272312 0.9232564321051762 1.2409692933588181 1.1285098288008621 1.0101339740472253 1.1313683076290553 0.8993412628735293 0.9884147398512761 0.967136308607276 1.0 13.581695107202483 -7.253754900906714 24.74175116085406 0.9627576382384575 1.0968421892584919 0.38430374565130265 0.08532861414320922 550.8521447102711 1773584.912143889 0.03225426807050145 0.024493063326922387 5.575002918769053e-08 7.253754900906714 0.13408455102003436 SNTPESIAET(ph)PPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNTPESIAETPPAR 14 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 SNTPES(0.006)IAET(0.993)PPAR;SNTPESIAET(1)PPAR 120.54 0.00020827 20294000.0 30326.0 29586.0 23698.0 30506.0 37246.0 36923.0 41573.0 28477.0 38971.0 32688.0 True False 35459.59283419767 32523.102552937748 24263.050195165466 28796.847721786424 29947.913672648152 34986.692880773364 37634.9044775446 27729.508923875575 39540.87714911141 38614.075641934396 0.9183074369826167 0.8422602901212032 0.628347300610146 0.7457603799406611 0.7755698712136229 0.9060606087065893 0.9746421182402609 0.7181191952128897 1.0240016494443938 1.0 15.236839215572026 -6.764628956256822 7.500513930952486 0.9103790374970857 0.7746177411542333 0.3113758946257559 0.10463795509183516 0.1762339025559215 63.20483887102999 0.03646929721777205 0.03401520192624825 1.7193767261653147e-07 6.764628956256822 -0.1357612963428524 SNTPESIAET(ph)PPAR ddPTM_PC-9_Lapatinib_30min_R1 2 SNTPESIAETPPAR 14 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 SNTPESIAET(1)PPAR;SNTPESIAET(1)PPAR 146.27 4.7343000000000004e-05 27048000.0 21130.3 18062.7 19629.5 25014.0 30075.0 33570.0 27872.0 30019.0 34199.0 23720.0 True False 20828.978047177567 18020.876927918987 18015.63828206123 26853.613004257844 28306.04762972499 32134.289355492147 29315.075781256608 31413.79232974735 30347.148488564664 27819.970395086708 0.7487059745705616 0.6477676529483891 0.6475793477207645 0.965263895787627 1.0174722412617712 1.1550799263671176 1.0537421630913724 1.1291813716414072 1.0908404307261335 1.0 14.763833264171359 -5.909350281879957 2.7571979725585756 1.0822183032362092 0.6744050322171178 0.9131852784445046 0.053942498329386024 0.06794778244813404 1.0449379749817882 0.01617031851893968 0.025845585742914297 1.2321106687740174e-06 5.909350281879957 -0.4078132710190914 SNTPILVDGK ddPTM_PC-9_Lapatinib_30min_R1 1 SNTPILVDGK 10 0 P06744-2;P06744;A0A2U3TZU2;K7EQ48;A0A0J9YXP8;A0A2R8Y6C7;A0A0J9YYH3;A0A0J9YX90;K7EPY4;K7ERC6;K7EP41 P06744-2 GPI Glucose-6-phosphate isomerase 0 122.69 0.002385 6846100.0 63984.0 55525.0 79538.0 61457.0 63664.0 48386.0 62791.0 52784.0 47215.0 62819.0 False True 63071.57642677143 55396.4352739458 72998.69266555867 65976.75279454213 59919.408688239804 46316.643573275025 66042.01074127734 55236.53733746577 41897.14950400831 73677.18044894403 0.8560530688396533 0.7518804999919044 0.990791072904106 0.8954842244575572 0.8132695676344737 0.6286429976154015 0.8963699525261065 0.7497102495085701 0.5686584265129652 1.0 16.168930231557425 -6.522604389481988 24.999814097489462 0.7565632032619621 0.8708782589185502 0.12901326940304247 0.12644798837756352 19.032296253236623 1734483.1313502667 0.04045851712115882 0.040893806978661296 3.001895781460028e-07 6.522604389481988 0.11431505565658806 SNVASSAACS(ph)SASSLGLGLAYR ddPTM_PC-9_Lapatinib_30min_R1 1 SNVASSAACSSASSLGLGLAYR 22 0 Q16352 Q16352 INA Alpha-internexin 1 SNVASSAACS(0.396)S(0.396)AS(0.204)S(0.004)LGLGLAYR 120.52 0.00011551 0.0 7657.8 3883.9 6770.5 6085.0 5135.7 4909.5 3312.1 4623.3 4966.7 5090.6 True False 7548.5983677314725 3874.9070681761063 6213.855624885786 6532.511198964941 4833.628223174684 4699.532129603473 3483.5843317702333 4838.115396186449 4407.297944330362 5970.503427201877 1.2643152222875755 0.6490084321067231 1.040759075118387 1.0941307175543242 0.8095846995334531 0.7871249362645363 0.5834657620157908 0.8103362564275204 0.7381786139256731 1.0 12.54363686796232 -6.418033908732708 5.408462543396399 0.7631986747683287 0.9873437941161357 0.28067862841753644 0.1724810740765951 0.30483222739093596 12.9474155746573 0.05252444280182914 0.0593966859634094 3.819144506577968e-07 6.418033908732708 0.224145119347807 SNVS(ph)SPATPTASSSSSTTPTR ddPTM_PC-9_Lapatinib_30min_R1 1 SNVSSPATPTASSSSSTTPTR 21 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 S(0.008)NVS(0.87)S(0.102)PAT(0.02)PTASSSSSTTPTR 223.82 5.885100000000001e-41 4964500.0 21869.0 21301.0 25769.0 19992.0 25923.0 25037.0 24289.0 22239.0 24903.0 22056.0 True False 21557.14404971656 21251.67884322953 23650.372291216598 21462.278371356966 24398.260106578935 23966.225874097607 25546.56557301026 23272.305127460986 22098.161899784376 25868.350212227357 0.8333405057863724 0.8215320524454769 0.9142590113859532 0.8296732569057402 0.943170318416613 0.9264690510788485 0.9875606818147608 0.899643964015174 0.8542547831032185 1.0 14.658900426748184 -5.8798390198010795 1.0162112837018218 0.9330456557518756 0.8302741175861624 0.40938591245241296 0.0474142628030318 0.6451124987943304 1.314517886222942 0.019326810970262048 0.04835381989596834 1.3187454681542012e-06 5.8798390198010795 -0.10277153816571316 SNVSDAVAQSTR ddPTM_PC-9_AZD4547_30min_R2 2 SNVSDAVAQSTR 12 0 P60174;P60174-3;P60174-4 P60174 TPI1 Triosephosphate isomerase 0 ; 94.68799999999999 0.022258 23470000.0 61413.0 45473.0 63854.0 77483.0 65528.0 75147.0 64027.0 81217.0 67482.0 71715.0 False True 80941.05653024535 60171.257977018686 63007.254238537585 59620.491450416695 56430.5682956139 70448.04621053854 69725.27896326577 68666.77883099394 71048.96075276656 69204.27967834697 1.16959611322377 0.8694730767618323 0.910453147282041 0.8615145151069479 0.8154202103958929 1.0179723932966638 1.0075284258045938 0.9922331270572966 1.0266555924430316 1.0 16.078573638217975 SNVSDAVAQSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNVSDAVAQSTR 12 0 P60174;P60174-3;P60174-4 P60174 TPI1 Triosephosphate isomerase 0 ; 103.14 0.01009 15286300.0 44980.0 39161.0 54962.0 52849.0 50968.0 64885.0 53608.0 48862.0 55777.0 49149.0 False True 52594.225604504776 43048.64527396726 56272.502524545715 49888.0418687698 40981.18627684937 61482.31637648563 48529.86215169008 47579.42427356841 56592.63310528311 58059.324636730045 0.9058704339669862 0.7414596284630809 0.969224200877908 0.8592597688814511 0.7058502063753503 1.0589567956770565 0.8358668044338334 0.8194966884521467 0.9747380538677665 1.0 15.825240169755373 -6.759307597642548 24.999999502913933 0.9201586382038875 0.839718712744934 0.20261274924989403 0.09744827995235178 119.28066343459146 1398840.529502593 0.03276263297786029 0.031247713761360752 1.7405736410612998e-07 6.759307597642548 -0.08043992545895351 SNVSDAVAQSTR ddPTM_PC-9_Lapatinib_30min_R1 3 SNVSDAVAQSTR 12 0 P60174;P60174-3;P60174-4 P60174 TPI1 Triosephosphate isomerase 0 ;; 120.84 0.0021857 72897200.0 120310.0 117826.0 115490.0 102158.0 110249.0 115532.0 127262.0 113992.0 114519.0 89725.0 False True 118594.35733784825 117553.18113620784 105994.8580042921 109671.0401090981 103764.3705778738 110590.96567824592 133851.0036622517 119288.48446825524 101620.66428146845 105233.84669895281 1.1269602039457558 1.1170662750027327 1.0072316210916088 1.0421650785306649 0.9860360885097852 1.050906805627076 1.271938714215829 1.1335562483951496 0.9656652062922231 1.0 16.683239272328798 SNVSS(ph)PATPTASSSSSTTPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNVSSPATPTASSSSSTTPTR 21 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVS(0.011)S(0.986)PAT(0.003)PTASSSSSTTPTR 148.15 0.00011022 5030900.0 10358.0 11484.0 9769.2 10696.0 12776.0 12715.0 8940.6 8654.5 8727.7 10977.0 True False 12111.404820174752 12624.055624888022 10002.134777897314 10096.737796899877 10272.634513283385 12048.203016521764 8093.681643661399 8427.32854520073 8855.326101313785 12967.043206115814 0.9340143799677088 0.9735492836897448 0.7713504627778118 0.7786461135671872 0.7922110191194837 0.929140346416006 0.6241732610132795 0.6499036373400869 0.6829102024690744 1.0 13.662561927899041 -5.2665449289166 22.572832778676762 0.7663956719828291 0.9537818610007752 0.2797778945380123 0.1111066185597496 121.59582514188456 537617.3591665344 0.029402635245531165 0.06463697472332124 5.413212438667223e-06 5.2665449289166 0.18738618901794613 SNVSSPAT(ph)PTASSSSS(ph)TTPTRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNVSSPATPTASSSSSTTPTRK 22 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 2 SNVS(0.003)S(0.012)PAT(0.985)PT(0.007)AS(0.025)S(0.083)S(0.068)S(0.067)S(0.317)T(0.314)T(0.098)PT(0.021)RK 77.66 0.0024851999999999995 6774100.0 14323.0 11841.0 14694.0 18259.0 20497.0 26133.0 19915.0 21787.0 21698.0 15067.0 True False 16747.601007855086 13016.496225557223 15044.360687305329 17236.00742647669 16480.759988945632 24762.539475482758 18028.50702788592 21215.11433523465 22015.292201416945 17798.527829693634 0.9409542838658113 0.7313243179495748 0.8452587107910423 0.9683951162366092 0.9259619754309374 1.3912689696824772 1.0129212483410346 1.1919589383028106 1.2369164692760937 1.0 14.119470295986362 -6.594513911879033 8.836762357933729 1.1689222660247522 0.8704139033979326 0.5898380447237355 0.11918597683261146 0.2015559400548076 22.681783881700337 0.03842602674945321 0.03841591033484991 2.5438183049671844e-07 6.594513911879033 -0.2985083626268197 SNVSSPAT(ph)PTASSSSS(ph)TTPTRK ddPTM_PC-9_Lapatinib_30min_R1 1 SNVSSPATPTASSSSSTTPTRK 22 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 2 S(0.002)NVS(0.087)S(0.257)PAT(0.559)PT(0.063)AS(0.03)S(0.038)S(0.035)S(0.035)S(0.326)T(0.31)T(0.121)PT(0.137)RK 68.676 0.0077635000000000004 10017000.0 21602.0 18542.0 22634.0 19119.0 23597.0 23138.0 19108.0 20560.0 24129.0 17859.0 True False 21293.951518678383 18499.067138217084 20773.119889766625 20525.075039114337 22209.070853486963 22148.441677312403 20097.31874383795 21515.29265797014 21411.337930365695 20945.904354378326 1.016616478258066 0.8831830235274717 0.9917509188580066 0.9799087540865228 1.0603061332534252 1.0574115732884415 0.959486800083521 1.027183753633096 1.0222207438797017 1.0 14.354380554487262 -5.780594722727953 2.34257811138646 1.0203164168161576 0.9505825064699007 0.2727251744260626 0.04195293569002415 0.34281997779349216 3.838231623970683 0.01226780407495895 0.022492105969422208 1.6573158250092465e-06 5.780594722727953 -0.06973391034625687 SNVSSPAT(ph)PTASSSSST(ph)TPTRK ddPTM_PC-9_AZD4547_30min_R2 1 SNVSSPATPTASSSSSTTPTRK 22 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 2 S(0.036)NVS(0.107)S(0.331)PAT(0.514)PT(0.008)AS(0.029)S(0.029)S(0.026)S(0.039)S(0.128)T(0.389)T(0.339)PT(0.025)RK 62.67 0.008695 11674000.0 16214.0 15706.0 20266.0 33392.0 35358.0 26162.0 22703.0 24254.0 22375.0 28316.0 True False 21369.71472784914 20782.657352430146 19997.25959843082 25693.990301257207 30449.15202350624 24526.08600423314 24723.5230184613 20506.101601474187 23557.69682053216 27324.665458719603 0.7820668384809017 0.7605823165091367 0.7318391373772327 0.9403222279179989 1.1143467454160387 0.8975804677750079 0.9048060645357965 0.7504612136040064 0.8621403565259256 1.0 14.737916212354197 -5.762749495296595 24.995424290692362 0.9198402499785684 0.7584046989269922 0.42341053008522267 0.08870643627788628 37.88058875105745 722741.0979468325 0.027419713887074728 0.043345528863149387 1.726833656931248e-06 5.762749495296595 -0.16143555105157614 SNVSSPAT(ph)PTASSSSSTT(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 1 SNVSSPATPTASSSSSTTPTR 21 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 2 SNVS(0.004)S(0.022)PAT(0.819)PT(0.08)AS(0.018)S(0.021)S(0.038)S(0.049)S(0.042)T(0.081)T(0.616)PT(0.21)R 125.04 2.939e-05 0.0 3775.8 4605.1 5104.2 6167.0 6739.9 4426.3 4410.1 7198.1 5392.1 6240.2 True False 4976.425858481116 6093.608517361263 5036.514972974964 4745.293429200207 5804.181224142475 4149.522761277317 4802.590356504258 6085.799040882799 5677.1153978096745 6021.732497369059 0.8264109806696585 1.0119361031104597 0.8363896893751849 0.7880279356935005 0.9638723119431768 0.6890911814980614 0.7975429593729955 1.0106392211114876 0.9427711045434266 1.0 12.555962905496033 -7.767041585777791 24.99863316170081 0.9825289006671506 0.8472742556288553 0.353273937525482 0.08657004548865156 168.71985278368572 752858.4734036025 0.047075616428881896 0.023608712049923885 1.709851580768736e-08 7.767041585777791 -0.13525464503829532 SNVSSPAT(ph)PTASSSSSTTPTR ddPTM_PC-9_AZD4547_30min_R2 1 SNVSSPATPTASSSSSTTPTR 21 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVSSPAT(0.644)PT(0.285)AS(0.036)S(0.036)SSSTTPTR 201.14 4.1748999999999996e-19 4726100.0 6795.5 6175.6 8361.4 13804.0 10851.0 8873.9 7106.2 12685.0 9259.1 8525.2 True False 8956.327644819217 8171.741929559883 8250.522372758298 10621.701069674014 9344.52595189395 8319.013630187466 7738.638033466495 10724.824722301484 9748.517123172713 8226.735342868922 1.0886855200201278 0.9933152810906081 1.002891430062837 1.2911198217748783 1.1358729267976206 1.0112168780777095 0.9406693798864554 1.3036550071588178 1.184980033619642 1.0 13.006104316881613 SNVSSPAT(ph)PTASSSSSTTPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNVSSPATPTASSSSSTTPTR 21 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVS(0.043)S(0.114)PAT(0.83)PT(0.005)AS(0.002)S(0.002)S(0.001)S(0.001)S(0.001)T(0.001)TPTR;SNVSSPAT(0.743)PT(0.147)AS(0.085)S(0.024)SS(0.001)S(0.001)TTPTR 188.27 2.2872e-52 4272900.0 11168.4 11241.5 12994.7 12390.0 16872.6 11673.4 13441.3 10863.3 13726.900000000001 11023.3 True False 13058.989534045148 12357.481827514697 13304.542930674188 11695.828468921974 13566.535150972542 11061.226354153769 12168.042757415162 10578.149885617775 13927.629943756576 13021.737029605214 1.002860793790816 0.9489887408584341 1.0217179858897478 0.8981772894300694 1.0418375920300584 0.849443229348421 0.9344408299561603 0.8123455312888067 1.0695677475356624 1.0 13.668634288640261 -6.756173829601281 24.99879773088874 0.9215111514194116 0.9783128306599291 0.08313298672049918 0.07691747480939057 286.9158781046844 1362163.739908789 0.024134028365604968 0.023452831282182663 1.7531786385792586e-07 6.756173829601281 0.05680167924051749 SNVSSPAT(ph)PTASSSSSTTPTR ddPTM_PC-9_Lapatinib_30min_R1 1 SNVSSPATPTASSSSSTTPTR 21 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVSSPAT(0.388)PT(0.239)AS(0.059)S(0.059)S(0.059)S(0.059)S(0.059)T(0.059)T(0.015)PT(0.002)R 146.68 6.176e-06 8534600.0 19622.0 17977.0 20999.0 20063.0 24588.0 24779.0 24431.0 22073.0 25305.0 20838.0 True False 19342.1866817659 17935.375361003596 19272.543278484125 21538.499948206005 23141.782181867922 23719.259932670233 25695.917638198905 23098.592161448185 22454.884426536708 24439.820535110342 0.7914209784797248 0.7338587177936747 0.7885713911359175 0.8812871566410936 0.946888384414376 0.9705169437965001 1.051395512552314 0.9451211856594715 0.9187827052280492 1.0 14.576946070841242 -5.971564237177435 1.6855168486741197 0.9770511752296713 0.7585701919873533 0.8671027572780663 0.035449965201120745 0.1270006726083727 0.72969616964977 0.0124269522175263 0.021345035859892395 1.0676668605808325e-06 5.971564237177435 -0.21848098324231802 SNVSSPAT(ph)PTASSSSSTTPTRK ddPTM_PC-9_AZD4547_30min_R2 2 SNVSSPATPTASSSSSTTPTRK 22 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVS(0.002)S(0.019)PAT(0.974)PT(0.005)ASSSSSTTPTRK;SNVS(0.007)S(0.021)PAT(0.955)PT(0.017)ASSSSSTTPTRK 88.57 0.00018051 25090000.0 15906.900000000001 14854.0 19778.9 40067.0 31039.0 22944.0 17802.9 27972.0 22447.0 23468.0 True False 20964.963315925957 19655.265014198227 19516.61886269633 30830.172178979174 26729.770622139542 21509.30805294415 19387.32361121283 23649.57013261467 23633.50259354126 22646.39246310326 0.9257528919929839 0.867920356243126 0.8617981382462514 1.3613723346537148 1.1803103150176852 0.9497896006168881 0.8560888292826204 1.044297460231065 1.0435879636037506 1.0 14.46699362893313 SNVSSPAT(ph)PTASSSSSTTPTRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNVSSPATPTASSSSSTTPTRK 22 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVS(0.005)S(0.071)PAT(0.911)PT(0.01)AS(0.001)SSSSTTPTRK;S(0.001)NVS(0.029)S(0.075)PAT(0.872)PT(0.023)ASSSSSTTPTRK 79.695 0.00047187 20023200.0 40683.0 30183.0 37564.0 47229.0 54423.0 54228.0 47452.0 48408.0 51353.0 39356.0 True False 47569.82837412332 33179.36876750218 38459.66822226331 44582.91224848396 43759.20382877441 51384.18821706192 42957.00303727049 47137.34129251569 52103.94047466883 46490.931258075405 1.0232066144267762 0.7136739976947434 0.8272509752228919 0.9589593291001237 0.9412417141283549 1.1052518593749736 0.9239867190186457 1.0139040027151103 1.1207334218674843 1.0 15.504661704265244 -6.095905686242516 1.867498088034162 1.0231036119740686 0.843126547287934 0.38736465422142696 0.09104478036810444 0.3355630460264206 2.3232164806695024 0.0298050132152113 0.04458672841276646 8.018521790719817e-07 6.095905686242516 -0.1799770646861346 SNVSSPAT(ph)PTASSSSSTTPTRK ddPTM_PC-9_Lapatinib_30min_R1 2 SNVSSPATPTASSSSSTTPTRK 22 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVS(0.006)S(0.059)PAT(0.684)PT(0.25)AS(0.001)SSSSTTPTRK;SNVS(0.001)S(0.009)PAT(0.928)PT(0.059)AS(0.001)SSSSTTPTRK 80.355 0.00042953 17874100.0 44658.0 27952.2 33240.0 25406.2 27852.9 36938.0 29215.0 30272.0 36962.0 24469.4 True False 44021.16873072582 27887.47839827806 30507.135510110566 27274.656700598684 26214.647182908306 35358.24784668362 30727.609749907155 31678.547633369246 32798.95033288478 28698.903186574007 1.533897251910307 0.971726278770279 1.0630070184836364 0.9503727903217702 0.913437249238574 1.2320417828101877 1.0706893413362997 1.1038243318019618 1.1428642453565565 1.0 14.80870798064806 -4.755561428404192 24.999999999950386 1.0524144158902344 1.5338980299445442 0.7187378325854831 0.09084127422368331 108.33708205708419 460731.5042451061 0.023584947031055223 0.20681438251461715 1.755652549892533e-05 4.755561428404192 0.4814836140543097 SNVSSPATPT(ph)ASSSSST(ph)TPTRK ddPTM_PC-9_Lapatinib_30min_R1 1 SNVSSPATPTASSSSSTTPTRK 22 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 2 S(0.001)NVS(0.005)S(0.019)PAT(0.179)PT(0.573)AS(0.095)S(0.088)S(0.09)S(0.104)S(0.114)T(0.305)T(0.275)PT(0.152)RK 52.721000000000004 0.040861 9882900.0 22403.0 20746.0 22874.0 19466.0 23980.0 22994.0 19357.0 19233.0 26078.0 19087.0 True False 22083.529111792952 20697.963911630446 20993.388016193425 20897.594576672396 22569.54354649396 22010.60022163201 20359.210745471577 20126.635393518467 23140.82102648583 22386.16251817118 0.9864812289228859 0.9245874050467383 0.9377841333525915 0.9335049971029876 1.008191713437885 0.9832234624297791 0.9094551479712392 0.8990659018570681 1.0337109367316566 1.0 14.45031961919596 -8.279097309631531 24.993201394698705 1.0168554807242363 0.9481209596211089 0.39567962491018305 0.03414111282872865 1027.5470365053106 1454385.4649275984 0.03445547892675794 0.00896977390716096 5.2589941821531175e-09 8.279097309631531 -0.06873452110312739 SNVSSPATPT(ph)ASSSSSTTPTR ddPTM_PC-9_AZD4547_30min_R2 1 SNVSSPATPTASSSSSTTPTR 21 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVSS(0.095)PAT(0.025)PT(0.587)AS(0.168)S(0.048)S(0.014)S(0.027)S(0.027)T(0.008)TPTR 154.56 4.0192e-05 7838800.0 17820.0 13819.0 25488.0 34078.0 32862.0 26782.0 21122.0 31787.0 25194.0 26037.0 True False 23486.389320973954 18285.721504726345 25150.01246643663 26221.84359985156 28299.678539410106 25107.31730622171 23001.81708126413 26875.049542593395 26525.7034054296 25125.452555046017 0.9347648274003771 0.7277768018174053 1.0009774913043579 1.0436366685297913 1.126335077046268 0.9992782120527153 0.9154787174826273 1.0696344467314283 1.0557303733063452 1.0 14.616861961633678 -5.393981305270699 6.261306345804435 1.0301594297527998 0.8328134735632496 0.5604247244495106 0.06945068250298449 0.15760825067312415 7.279311106183905 0.018287054259291814 0.03856021806130358 4.036627687439186e-06 5.393981305270699 -0.1973459561895502 SNVSSPATPTAS(ph)SSSSTTPTR ddPTM_PC-9_Lapatinib_30min_R1 2 SNVSSPATPTASSSSSTTPTR 21 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVSSPATPT(0.077)AS(0.284)S(0.163)S(0.095)S(0.095)S(0.095)T(0.095)T(0.095)PT(0.001)R;SNVSSPATPT(0.018)AS(0.447)S(0.447)S(0.018)S(0.018)S(0.018)T(0.018)T(0.015)PTR 157.62 3.8273e-06 21672300.0 53928.0 38066.0 51024.0 45479.0 55339.0 50425.0 45841.0 47207.0 51933.0 41955.0 True False 53158.97683081603 37977.86051576806 46829.003678335815 48823.677373496575 52084.06882066004 48268.44029641616 48214.42267826435 49400.40955762629 46083.758661265805 49206.86584847651 1.0803162508766422 0.771800029546972 0.9516762116599158 0.9922127030776581 1.0584715755123146 0.9809289712750644 0.979831205399909 1.003933266340225 0.9365310687165539 1.0 15.586572008822703 -5.522778831327744 17.47099371080829 0.9931847165526324 0.9099788855202829 0.11260410702704382 0.07488101758593618 0.14548615657089647 20743.57904942101 0.019038806372972242 0.03389334366381083 3.0006902605312258e-06 5.522778831327744 -0.08320583103234946 SNVSSPATPTASSS(ph)SSTTPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNVSSPATPTASSSSSTTPTR 21 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVSSPATPT(0.008)AS(0.008)S(0.008)S(0.195)S(0.195)S(0.195)T(0.195)T(0.195)PTR 171.52 5.6255e-09 12232000.0 30628.0 34295.0 33385.0 38585.0 43866.0 38751.0 47279.0 37418.0 35095.0 34361.0 True False 35812.71546942577 37699.58095224094 34181.02501331755 36423.20754425782 35270.7721947158 36718.829342763274 42800.390849682044 36435.81714764814 35608.19798178301 40590.377298473664 0.8822957028973576 0.9287812398250009 0.8420967551489814 0.8973360182495139 0.8689441819020022 0.9046190695089702 1.054446735859523 0.8976466732428784 0.8772571321509247 1.0 15.308850129885796 -7.016008994308727 24.60556259193594 0.9531974360251974 0.885006937505271 0.3209960048988506 0.050467375745066 779.4597984163366 1198015.2151003892 0.019083567230767706 0.015238278514991817 9.638090627762219e-08 7.016008994308727 -0.06819049851992631 SNVSSPATPTASSS(ph)SSTTPTRK ddPTM_PC-9_AZD4547_30min_R2 1 SNVSSPATPTASSSSSTTPTRK 22 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVSSPATPTAS(0.039)S(0.105)S(0.333)S(0.063)S(0.063)T(0.198)T(0.198)PT(0.001)RK 142.85 3.9879e-05 52971000.0 9315.6 7784.9 12207.0 14657.0 14514.0 11809.0 11806.0 11353.0 12199.0 12324.0 True False 12277.76702348288 10301.21668298315 12045.127204087892 11278.055098392644 12498.981629876393 11070.581363198122 12856.711128747495 9598.654715986493 12843.814235247908 11892.540511133653 1.032392280857785 0.8661914309511306 1.0128304539144843 0.9483301812454845 1.050993403652903 0.9308844777811752 1.0810735617600964 0.8071155786268164 1.079989109410532 1.0 13.537769319301116 SNVSSPATPTASSS(ph)SSTTPTRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNVSSPATPTASSSSSTTPTRK 22 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVSSPATPT(0.03)AS(0.054)S(0.092)S(0.259)S(0.156)S(0.156)T(0.156)T(0.095)PT(0.001)RK 122.59 2.8586e-07 40976000.0 21919.0 19844.0 19514.0 27200.0 29770.0 35829.0 31047.0 25457.0 24800.0 19955.0 True False 25629.453780016447 21813.981175572797 19979.287767257123 25676.07218358981 23936.782205733114 33950.064166650256 28106.00339918525 24788.78072392107 25162.6530830095 23572.68353630693 1.087252274037517 0.9253923568767486 0.8475610227611458 1.0892299192004684 1.0154457878699044 1.4402290733831793 1.1923124219563737 1.0515892552386363 1.067449662413432 1.0 14.524828385237432 -6.187445934796575 2.3596497208294944 1.1543024085913285 0.9570382818407477 0.23741669152582923 0.13280513363079924 0.401242383199608 4.382239416777895 0.044971150576928236 0.060420951405002574 6.494624779533067e-07 6.187445934796575 -0.1972641267505808 SNVSSPATPTASSSS(ph)STTPTRK ddPTM_PC-9_Lapatinib_30min_R1 1 SNVSSPATPTASSSSSTTPTRK 22 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVSSPATPT(0.003)AS(0.03)S(0.019)S(0.065)S(0.221)S(0.221)T(0.221)T(0.221)PT(0.001)RK 122.84 2.7036e-07 12497000.0 29288.0 23187.0 35307.0 27382.0 29212.0 29870.0 26322.0 25768.0 34229.0 24525.0 True False 28870.3477492386 23133.31192610502 32404.194748961323 29395.763623674284 27493.807593001715 28592.529730370876 27684.824365464843 26965.275350708867 30373.769572650654 28764.11357249166 1.0036932887390813 0.8042421285746968 1.1265493952141403 1.021959656416692 0.9558371240508244 0.9940347947212641 0.9624779256865754 0.9374624141554253 1.0559605633631755 1.0 14.811982390731957 -5.2520787461642175 24.99705947434986 1.0012363421921793 0.9039677327926648 0.2630273545969706 0.06833868777259897 912.2060200170698 2435983.6757947756 0.01700731740919127 0.04362448985223632 5.596561155911617e-06 5.2520787461642175 -0.09726860939951443 SNVSSPATPTASSSSS(ph)TTPTRK ddPTM_PC-9_AZD4547_30min_R2 2 SNVSSPATPTASSSSSTTPTRK 22 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVSSPATPT(0.004)AS(0.035)S(0.041)S(0.177)S(0.138)S(0.201)T(0.201)T(0.201)PT(0.001)RK;SNVSSPATPT(0.055)AS(0.072)S(0.05)S(0.05)S(0.072)S(0.233)T(0.233)T(0.233)PT(0.003)RK 81.726 0.00018447 68186000.0 34648.0 30187.0 46056.0 69640.0 63724.0 41922.0 41144.0 52637.0 43014.0 46481.0 True False 45665.34327682971 39944.3574110409 45445.2673475442 53585.573927274614 54877.02255630728 39300.61071284542 44805.73629351066 44503.161127929285 45287.6322251786 44853.714337715326 1.0180950218080809 0.8905473716243298 1.0131884955028454 1.1946741695417873 1.2234666262669764 0.8761952336196922 0.9989303440102323 0.9921845221747605 1.0096740681094143 1.0 15.452939839269698 -6.792477016289924 24.9997794216354 0.9763793178829244 1.0621295810540536 0.19136050995133214 0.09478092342001822 433.2771531233573 348987.16100545594 0.03771770756522173 0.03326710536099008 1.6125863662917192e-07 6.792477016289924 0.08575026317112922 SNVSSPATPTASSSSS(ph)TTPTRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNVSSPATPTASSSSSTTPTRK 22 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVSSPATPT(0.002)AS(0.07)S(0.017)S(0.049)S(0.148)S(0.273)T(0.212)T(0.212)PT(0.017)RK 82.831 0.00014619 15461000.0 11323.0 15654.0 12738.0 17759.0 15109.0 16164.0 16584.0 16045.0 10907.0 9699.5 True False 13239.76026055597 17208.0256663181 13041.722229134015 16764.02080545484 12148.499910864015 15316.331384904277 15013.043462237509 15623.835751082754 11066.494240983244 11457.942568800247 1.1555093928125961 1.501842548345042 1.1382254842720516 1.4630917116920221 1.0602688779348697 1.3367435988560763 1.3102739319987282 1.363581258787782 0.9658360717496605 1.0 13.484060391160185 -8.267497363358252 24.81886973430351 0.9829179697487594 1.2933018872347983 0.46153498734579346 0.13317494587293838 389.5940558951378 1596095.378065432 0.10745077405413374 0.03059257092630629 5.40135393966341e-09 8.267497363358252 0.3103839174860389 SNVSSPATPTASSSSS(ph)TTPTRK ddPTM_PC-9_Lapatinib_30min_R1 1 SNVSSPATPTASSSSSTTPTRK 22 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVSSPATPT(0.002)AS(0.02)S(0.016)S(0.016)S(0.062)S(0.248)T(0.248)T(0.248)PT(0.141)RK 91.20200000000001 9.1477e-05 50975000.0 27506.0 21081.0 31746.0 29388.0 26220.0 28787.0 25505.0 20646.0 28716.0 22569.0 True False 27113.759396017365 21032.188239712774 29135.96642310381 31549.291555494125 24677.791150503388 27555.847115774563 26825.52410307657 21605.288531928585 25481.701687114335 26470.0215786978 1.0243195048181457 0.7945663428033918 1.100715627921946 1.1918876402006393 0.9322920677315677 1.0410209539817905 1.0134303828699884 0.8162172617689064 0.9626626714812038 1.0 14.692071750486562 -7.619142897877093 24.999998216130987 0.9166235661772673 1.0136898365872344 0.12231896882379245 0.10676202364142967 30.405939477959414 7874.984689339225 0.05189205134120972 0.02995988639140608 2.4035718117815984e-08 7.619142897877093 0.09706627040996718 SNVSSPATPTASSSSST(ph)TPTR ddPTM_PC-9_Lapatinib_30min_R1 1 SNVSSPATPTASSSSSTTPTR 21 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVSSPATPT(0.004)AS(0.013)S(0.013)S(0.006)S(0.006)S(0.006)T(0.476)T(0.476)PTR 209.23 2.0078999999999997e-24 5005400.0 8067.8 9165.0 10581.0 10104.0 9697.3 7187.8 8903.1 8130.9 11091.0 8968.7 True False 7952.751692546677 9143.779005595921 9711.071023841156 10847.081865955925 9126.923879625341 6880.394549580176 9364.058954797129 8508.6912973098 9841.814786592322 10518.927844958444 0.7560420424747286 0.8692691061645024 0.9231996993396546 1.0311965274250607 0.8676667445722362 0.65409656297603 0.890210399084083 0.8088933989016649 0.9356290804209051 1.0 13.360700043154166 -8.49887500986558 4.633272697011811 0.9997409260915554 0.8549286005799969 0.21118102484182932 0.09467905300701439 0.2874230710086782 17.372248421409605 0.09738804021724573 0.02539301422266807 3.170479797170255e-09 8.49887500986558 -0.14481232551155854 SNVSSPATPTASSSSST(ph)TPTRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNVSSPATPTASSSSSTTPTRK 22 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVSSPATPT(0.006)AS(0.108)S(0.041)S(0.041)S(0.041)S(0.108)T(0.288)T(0.288)PT(0.079)RK 57.058 0.009565 7441200.0 9343.6 9058.6 10806.0 10535.0 11461.0 12617.0 10635.0 12495.0 10798.0 8763.3 True False 10925.286935488006 9957.877941798211 11063.656021983217 9944.758104930834 9215.299323476896 11955.342309040903 9627.575809267719 12167.019489546836 10955.900322190982 10352.01691975537 1.0553776157995483 0.9619263587943911 1.0687440049358676 0.9606589886800379 0.8901936110528175 1.15488048384328 0.9300193270448431 1.1753284006257552 1.0583348546584372 1.0 13.337624259993591 -6.766069310218403 24.99962162152872 1.066314785490904 0.98900173226486 0.18298325681240557 0.0805168834231823 205.6726856388334 1110536.3393846806 0.027014430057402686 0.024611257608824624 1.7136837943016402e-07 6.766069310218403 -0.07731305322604409 SNVSSPATPTASSSSST(ph)TPTRK ddPTM_PC-9_Lapatinib_30min_R1 2 SNVSSPATPTASSSSSTTPTRK 22 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVSSPATPT(0.139)AS(0.043)S(0.028)S(0.106)S(0.106)S(0.07)T(0.402)T(0.106)PT(0.001)RK;SNVSSPATPTAS(0.005)S(0.009)S(0.024)S(0.024)S(0.194)T(0.549)T(0.194)PT(0.001)RK 130.51 8.734299999999999e-06 63623000.0 48587.0 38263.0 50705.0 35327.0 44241.0 37355.0 36031.0 36928.0 41335.0 30505.0 True False 47894.14047023542 38174.4043743717 46536.23062696019 37925.065427417314 41638.83136115256 35757.41372875809 37896.50887896301 38643.809692291885 36679.41702315333 35777.74860464253 1.338657191638399 1.06698732768831 1.3007031588600753 1.0600182210038824 1.1638192168343844 0.9994316334404059 1.059220055955269 1.080107362800281 1.0252019328682351 1.0 15.126774984962987 -1.522878763851 0.24653209185908048 1.0025873339590525 2.714216797580923 0.5314774709812645 0.07830765372539135 39.96581891523056 0.5402977975820292 0.09690565867455304 28.235224421081586 0.029999998717184114 1.522878763851 1.7116294636218705 SNVSSPATPTASSSSSTT(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 4 SNVSSPATPTASSSSSTTPTR 21 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVSSPATPTAS(0.001)S(0.003)S(0.003)S(0.008)S(0.004)T(0.085)T(0.896)PT(0.001)R;SNVSSPATPT(0.025)AS(0.025)S(0.025)S(0.116)S(0.075)S(0.049)T(0.227)T(0.446)PT(0.013)R;SNVSSPATPTASSSS(0.001)S(0.028)T(0.095)T(0.876)PTR;SNVSSPATPT(0.003)AS(0.009)S(0.004)S(0.004)S(0.093)S(0.093)T(0.093)T(0.703)PT(0.001)R 276.88 1.3661999999999998e-100 33269600.0 59468.1 54528.9 72413.0 113264.0 89443.0 76966.0 72968.1 89949.0 75055.0 81551.0 True False 78377.71878667847 72154.30055424215 71452.75630618627 87152.73471135601 77025.38334856239 72153.30385298566 79462.11954205988 76049.44887239217 79022.25407218056 78695.92431219267 0.9959565183547262 0.9168746816925435 0.9079600618543827 1.1074618599765667 0.9787722048094496 0.9168620164717559 1.009736148810295 0.9663708703731373 1.004146717416944 1.0 16.264001299566225 SNVSSPATPTASSSSSTT(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SNVSSPATPTASSSSSTTPTR 21 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVSSPATPTAS(0.001)S(0.002)S(0.001)S(0.001)S(0.003)T(0.083)T(0.908)PT(0.001)R;SNVSSPATPT(0.007)AS(0.007)S(0.027)S(0.072)S(0.072)S(0.072)T(0.298)T(0.444)PT(0.001)R;SNVSSPATPTASSSSST(0.004)T(0.996)PTR 282.18 4.719799999999999e-102 19395500.0 51635.0 64958.0 72662.0 71339.0 80682.0 74093.0 72875.0 65431.0 69870.0 61399.0 True False 60375.785662263275 71406.60094753356 74394.53765216969 67342.10711415854 64872.941280583094 70207.43264672806 65971.7524306896 63713.5055798751 70891.7165689464 72530.1526657833 0.8324232535463288 0.9845091775357618 1.0257049643198384 0.9284705000480129 0.8944271988439843 0.96797580132282 0.9095769139586041 0.8784416306617326 0.977410276462718 1.0 16.146293265130453 SNVSSPATPTASSSSSTT(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 1 SNVSSPATPTASSSSSTTPTR 21 0 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVSSPATPT(0.031)AS(0.031)S(0.053)S(0.032)S(0.032)S(0.032)T(0.113)T(0.673)PT(0.004)R 115.88 8.0529e-06 4364600.0 18031.0 14422.0 20188.0 17789.0 16283.0 18561.0 14545.0 15481.0 18081.0 16826.0 True False 17773.874633519576 14388.606745085037 18528.22056793357 19097.262402364402 15325.26595360971 17767.189297804278 15298.068930768419 16200.303776169061 16044.52737862914 19734.3516807643 0.9006566276430726 0.7291147425486528 0.9388816449437059 0.9677167363435157 0.7765781314492198 0.9003178612207728 0.7751999750607431 0.8209189761202043 0.8130253092767294 1.0 14.268421503679887 -6.295741620455815 24.967491530367802 0.8377278994431072 0.8769362525941413 0.03151776347427304 0.0856059137332129 2259.049994421297 1644283.0311406297 0.026248234491784816 0.029764386055191515 5.06125687313332e-07 6.295741620455815 0.0392083531510341 SNVSSPATPTASSSSSTT(ph)PTRK ddPTM_PC-9_AZD4547_30min_R2 1 SNVSSPATPTASSSSSTTPTRK 22 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVSSPATPT(0.002)AS(0.048)S(0.09)S(0.058)S(0.058)S(0.058)T(0.172)T(0.511)PT(0.002)RK 109.28 1.8698e-05 14282000.0 14729.0 14419.0 26624.0 31515.0 25580.0 24584.0 22775.0 25726.0 21389.0 20359.0 True False 19412.51561776798 19079.659771086866 26270.948364187443 24249.703651896292 22028.65854294048 23046.758593688075 24801.930878978816 21750.63782466912 22519.578873491046 19646.23760679732 0.9881034733618168 0.971161000541171 1.3371999713114568 1.234317946124516 1.1212660145838242 1.173087644308762 1.2624264948520065 1.1071146679577828 1.1462540219761768 1.0 14.261965432199691 SNVSSPATPTASSSSSTT(ph)PTRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SNVSSPATPTASSSSSTTPTRK 22 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVSSPATPTAS(0.015)S(0.01)S(0.01)S(0.027)S(0.027)T(0.071)T(0.839)PT(0.001)RK;SNVSSPATPTAS(0.056)S(0.097)S(0.07)S(0.05)S(0.05)T(0.237)T(0.435)PT(0.004)RK 110.44 1.4193e-05 63892000.0 34378.0 27696.2 33335.0 45476.0 50789.0 43875.0 43271.0 47884.0 41079.0 41044.0 True False 40197.51640354967 30445.695698190848 34129.83282369152 42928.12715518123 40837.26004188711 41574.11776247679 39172.05762508922 46627.09573729176 41679.70266116723 48484.952295874755 0.8290720006951475 0.6279411292889167 0.7039262948103465 0.8853907268633878 0.8422666849846868 0.8574643429321067 0.8079219586738068 0.9616817905224367 0.859642026804953 1.0 15.56524944403289 -6.203477464119389 0.22904598096292988 1.0123278915050524 0.5942519693488275 0.5328308158903247 0.0709440353859983 4.4259495195811365 0.3877732253080529 0.14923550959391424 0.5450460078333608 6.259253428347401e-07 6.203477464119389 -0.4180759221562249 SNVSSPATPTASSSSSTTPT(ph)RK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNVSSPATPTASSSSSTTPTRK 22 1 Q12888;Q12888-3;Q12888-2;A6NNK5;H7BZY0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 SNVSSPAT(0.001)PT(0.009)AS(0.016)S(0.002)S(0.005)S(0.011)S(0.244)T(0.244)T(0.124)PT(0.345)RK 93.196 0.00016099 5756500.0 9202.4 8307.2 9964.8 11059.0 14001.0 13837.0 11277.0 13109.0 12153.0 9464.8 True False 10760.184564315132 9131.883915627819 10202.398623714442 10439.400083761755 11257.604557019466 13111.363361353644 10208.760921590227 12764.902640133607 12330.71463378283 11180.693316684426 0.9623897427056881 0.8167547089410578 0.912501428555408 0.9336988134880263 1.0068789330103767 1.1726789198115442 0.9130704717887369 1.1416915104079581 1.1028577821182415 1.0 13.448722032268037 -6.2695602515364355 2.42842394801392 1.0668410906092936 0.892821674859799 0.4913568401653454 0.07647570549288761 0.23967630460132067 2.7868543882882357 0.024638894035818447 0.03115154689925646 5.37575847745242e-07 6.2695602515364355 -0.17401941574949453 SNVVSPT(ph)KNEDNGAPENSVEKPHEKPEAR ddPTM_PC-9_AZD4547_30min_R2 1 SNVVSPTKNEDNGAPENSVEKPHEKPEAR 29 3 Q71RC2-5;Q71RC2-3;Q71RC2;Q71RC2-4;X6RLN4;Q71RC2-2;Q71RC2-6 Q71RC2-5 LARP4 La-related protein 4 1 S(0.01)NVVS(0.071)PT(0.919)KNEDNGAPENSVEKPHEKPEAR 56.172 0.00082024 21124000.0 41754.0 31791.0 39706.0 40645.0 42936.0 42881.0 39847.0 36453.0 35419.0 43440.0 True False 55030.903462847746 42066.8190431113 39179.47249656049 31274.923208990178 36975.07752930777 40199.64429124385 43393.30580613256 30820.026456606705 37291.17603067838 41919.17882210694 1.3127858180710847 1.0035220208303914 0.9346431298863707 0.7460767144726773 0.8820563419483829 0.9589797658451207 1.035165931810864 0.7352249572301529 0.8895970073491067 1.0 15.355322834953489 -4.708134128674077 1.9449925442208174 0.8891050240488912 1.4969159118374984 0.6492326726845685 0.09185229509870431 0.6149727432367739 2.139810524884562 0.02543096636465097 0.7230516745883041 1.958239792068012e-05 4.708134128674077 0.6078108877886071 SNVVSPT(ph)KNEDNGAPENSVEKPHEKPEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SNVVSPTKNEDNGAPENSVEKPHEKPEAR 29 3 Q71RC2-5;Q71RC2-3;Q71RC2;Q71RC2-4;X6RLN4;Q71RC2-2;Q71RC2-6 Q71RC2-5 LARP4 La-related protein 4 1 S(0.002)NVVS(0.072)PT(0.915)KNEDNGAPENS(0.012)VEKPHEKPEAR 52.97 0.0022213000000000003 25271000.0 60083.0 68046.0 45867.0 107770.0 88084.0 87566.0 86347.0 92744.0 69526.0 64970.0 True False 70253.86520665762 74801.1571796527 46960.64323156618 101731.99629505404 70824.57251628472 82973.88480886714 78167.58706185596 90309.56827039066 70542.68621973052 76748.5466977631 0.9153771404078617 0.9746263662062651 0.6118766446027686 1.3255234225564703 0.9228132070720886 1.0811134331392556 1.0184894753731437 1.1766941806211793 0.9191403519017585 1.0 16.227851811572577 -5.75729643138771 24.999975907502993 1.0637680096050792 0.848026768851627 0.3493256317263683 0.14310892684556809 120.2067105920455 725356.4717873943 0.0372068185045537 0.06158501225753344 1.7486527234252743e-06 5.75729643138771 -0.21574124075345225 SNVVSPT(ph)KNEDNGAPENSVEKPHEKPEAR ddPTM_PC-9_Lapatinib_30min_R1 2 SNVVSPTKNEDNGAPENSVEKPHEKPEAR 29 3 Q71RC2-5;Q71RC2-3;Q71RC2;Q71RC2-4;X6RLN4;Q71RC2-2;Q71RC2-6 Q71RC2-5 LARP4 La-related protein 4 1 S(0.001)NVVS(0.009)PT(0.99)KNEDNGAPENSVEKPHEKPEAR;S(0.013)NVVS(0.22)PT(0.766)KNEDNGAPENS(0.001)VEKPHEKPEAR 62.646 0.00022331 89799000.0 144123.0 120100.0 134252.0 130724.0 152105.0 113071.0 114069.0 112716.0 133430.0 115579.0 True False 142067.77959107878 119821.91582892225 123214.31878770665 140337.87904248032 143158.48294993571 108235.2169113748 119974.93467609657 117953.19684998847 118401.70831981013 135556.67615066285 1.0480323332299712 0.8839248588225017 0.9089505754092226 1.0352708773008232 1.0560784390347837 0.798449917664535 0.8850536770520387 0.8701393409712318 0.873448004790365 1.0 17.048536641926496 -6.760786999510304 24.999983417465376 0.877279121786553 0.9791620797814408 0.3361972178232272 0.07014827751776015 21.42699394752966 821116.7826977796 0.024281809889102567 0.022921633395898852 1.7346545535243435e-07 6.760786999510304 0.10188295799488778 SPAAPGQS(ph)PTGSVCYER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPAAPGQSPTGSVCYER 17 0 O75534;O75534-4 O75534 CSDE1 Cold shock domain-containing protein E1 1 S(0.003)PAAPGQS(0.885)PT(0.084)GS(0.027)VCY(0.001)ER 82.94200000000001 0.0041294 5764300.0 12012.0 9510.4 11674.0 10815.0 14430.0 14190.0 12395.0 13459.0 10478.0 4637.5 True False 14045.394352185653 10454.52965995603 11952.35243389154 10209.070612703084 11602.545086621725 13445.851419932666 11220.855867971175 13105.715510989263 10631.220927571516 5478.242039570198 2.563850638714678 1.908373084730709 2.1817861181667095 1.863566914159939 2.1179321765659 2.4544098860202195 2.0482585082807914 2.39232137176938 1.940626363490431 1.0 12.419497293234325 -8.597736454706805 8.136794709339872 1.0000007513113085 2.17197291183717 0.7322391986067264 0.21559693708044855 1.4750079951373931 160.45214644551842 0.20033055691894952 0.05177741813214935 2.5250125748336124e-09 8.597736454706805 1.1719721605258615 SPAAPGQSPT(ph)GSVCYER ddPTM_PC-9_AZD4547_30min_R2 1 SPAAPGQSPTGSVCYER 17 0 O75534;O75534-4 O75534 CSDE1 Cold shock domain-containing protein E1 1 S(0.039)PAAPGQS(0.026)PT(0.831)GS(0.104)VCYER 175.56 1.3188e-05 6384100.0 10237.0 9839.7 13656.0 15550.0 12840.0 11056.0 10234.0 14400.0 10666.0 15000.0 True False 13492.153057172292 13020.190599179097 13474.912517328106 11965.187745105106 11057.387634533072 10364.666572234602 11144.806174115003 12174.810879080911 11229.78298492944 14474.854565644657 0.932109749081365 0.8995040703263346 0.9309186808211626 0.8266188576086893 0.7639031939413905 0.7160463357493497 0.7699425319662032 0.8411007394835742 0.7758131823709489 1.0 13.82126123253237 -5.86091521837914 4.254095005313203 0.7963268633529281 0.918787128575451 0.3026203434004052 0.07277367147420113 0.22912873238874282 7.45434742819696 0.020009565167356677 0.030982266403201862 1.3774783496962747e-06 5.86091521837914 0.12246026522252285 SPAAPYFLGSSFS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 2 SPAAPYFLGSSFSPVR 16 0 P30291 P30291 WEE1 Wee1-like protein kinase 1 SPAAPYFLGSSFS(1)PVR;SPAAPYFLGSS(0.009)FS(0.991)PVR 161.48 4.6759e-05 19911500.0 23683.0 21763.9 27627.0 30200.0 30151.0 34435.0 25291.0 35192.0 30542.0 26199.0 True False 31213.701362998116 28798.655058738994 27260.64792883887 23237.856585348833 25965.054094143812 32281.774006412663 27541.850004841002 29753.8850317094 32156.387767271197 25281.780984354955 1.2346322192377979 1.1391070540702957 1.078272450256115 0.919154255775297 1.0270263044447574 1.2768789519373454 1.089395166498936 1.1768903879881685 1.2719194026390164 1.0 14.625810477826843 -6.735496692948215 24.999993145215505 1.169471188246613 1.0739505937484217 0.13036696187418473 0.10652052987118027 444.47436837349403 428322.1783473076 0.03633119482039942 0.036319488989038334 1.838667954840886e-07 6.735496692948215 -0.09552059449819117 SPAAPYFLGSSFS(ph)PVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPAAPYFLGSSFSPVR 16 0 P30291 P30291 WEE1 Wee1-like protein kinase 1 SPAAPYFLGSSFS(1)PVR 170.79 2.709e-05 8457200.0 13433.0 17853.0 16082.0 14187.0 13690.0 12538.0 11701.0 12390.0 12908.0 10006.0 True False 15706.941586156343 19625.32785363339 16465.45587132464 13392.148384874577 11007.542774487283 11880.485208112452 10592.596572096061 12064.775628290141 13096.75508046317 11820.008592547587 1.3288434998312466 1.6603480192059241 1.393015558525564 1.1330066539307095 0.931263517137157 1.005116461218395 0.8961581109826436 1.020707855990636 1.108015698797424 1.0 13.528943463831501 -5.798974592075879 2.6482989456404824 0.9919078108208164 1.5014055948191016 0.8367886972267207 0.09265321311994516 0.09320235330487867 1.3320232499691353 0.026418640226219727 0.046163710747058405 1.5886396875081573e-06 5.798974592075879 0.5094977839982853 SPAAPYFLGSSFS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 1 SPAAPYFLGSSFSPVR 16 0 P30291 P30291 WEE1 Wee1-like protein kinase 1 SPAAPYFLGS(0.015)S(0.037)FS(0.948)PVR 106.31 0.0010335000000000001 7221800.0 4508.4 5396.4 4698.0 1776.0 7019.8 4829.5 6080.4 4738.0 4604.9 2309.2 True False 4444.109389260698 5383.904967353829 4311.748574804436 1906.6129645623218 6606.909165457809 4622.953543114365 6395.213360374308 4958.144776919381 4086.2476702532626 2708.3421431844117 1.6408965907222517 1.9878969061950005 1.5920250643571838 0.703977881583516 2.4394662181379876 1.7069311404203877 2.3613018674424016 1.83069365493449 1.5087634627465267 1.0 11.403194289858416 -6.293871624750203 24.999474741706823 1.8720196121649417 1.5253069714115772 0.08558670549109182 0.4887854335589062 1566.4447960680486 1207445.0607687302 0.15020521521633923 0.17032949867880753 5.083096741214626e-07 6.293871624750203 -0.3467126407533645 SPAFVGPGRPGEQPS(ph)PCQEGSQGGSR ddPTM_PC-9_Lapatinib_30min_R1 1 SPAFVGPGRPGEQPSPCQEGSQGGSR 26 1 I3L2J0 I3L2J0 CIC 1 SPAFVGPGRPGEQPS(0.835)PCQEGS(0.114)QGGS(0.051)R 51.938 0.0069145 4385700.0 3678.2 3469.9 5415.2 3792.8 3325.5 4871.6 4975.5 5615.4 4981.4 3815.4 True False 3625.7481935007304 3461.8656597400227 4969.983159276499 4071.735164409899 3129.9006281845536 4663.2530242542625 5233.107044691524 5876.311984025563 4420.342275532498 4474.886806299066 0.8102435548530418 0.7736208332391635 1.1106388551059014 0.9099079687732724 0.6994368268217992 1.042094074355142 1.169438976048545 1.3131755591568894 0.9878109697233485 1.0 12.127635474065485 -6.973008519815647 8.95969262377995 1.138447713672426 0.8720494038980495 0.45862423822154086 0.13229516829729687 0.23518794148726216 71.37209275140339 0.04785793549208898 0.04192632861599303 1.064122142496473e-07 6.973008519815647 -0.2663983097743765 SPAGLQVLNDYLADK ddPTM_PC-9_Lapatinib_30min_R1 3 SPAGLQVLNDYLADK 15 0 P24534;C9JZW3;F2Z2G2;F8WF65 P24534 EEF1B2 Elongation factor 1-beta 0 ;; 115.24 0.00075148 14374300.0 69641.7 71796.4 73826.0 63650.2 74513.8 62903.1 64810.9 62800.8 66181.7 65572.5 False True 68648.59658727635 71630.15984695777 67756.31125660116 68331.24803884282 70131.04478376725 60212.88104728799 68166.49127983082 65718.75443359198 58727.62002180302 76906.61925513585 0.8926227319853481 0.9313913488945138 0.8810205404013565 0.8884963180107496 0.911898682623263 0.7829349623019212 0.8863540217999979 0.8545266333392136 0.763622437061959 1.0 16.230820154012072 SPAGPAATPAQAQAAS(ph)TPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPAGPAATPAQAQAASTPR 19 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 SPAGPAATPAQAQAAS(0.849)T(0.151)PR 113.81 8.3289e-05 91600000.0 27073.0 39207.0 42175.0 34890.0 39973.0 30716.0 34530.0 33201.0 29131.0 28027.0 True False 31655.92418387633 43099.21184996384 43180.611949578175 32935.22641490621 32140.577598581443 29105.19888757235 31259.068424448957 32329.50892936732 29556.98576456248 33108.07323839009 0.9561391252200706 1.3017734840573156 1.3042321019004086 0.9947793149350819 0.9707776519387785 0.8790967290063787 0.9441524488414765 0.9764841552869348 0.8927425510914363 1.0 15.014895433464586 -5.894167927028433 5.755898247203323 0.9432366069982024 1.197356527048051 0.5616463912064587 0.09625856546740906 0.14309285032633454 6.783395260466494 0.02714829475895706 0.040791306970015304 1.2759453483836188e-06 5.894167927028433 0.2541199200498486 SPAGPAATPAQAQAAS(ph)TPRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPAGPAATPAQAQAASTPRK 20 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 SPAGPAATPAQAQAAS(0.5)T(0.5)PRK;SPAGPAAT(0.195)PAQAQAAS(0.403)T(0.403)PRK 95.624 0.00024122 6564600.0 14433.7 12874.3 21851.2 16339.9 20760.2 18490.6 16875.2 18181.0 16024.5 9473.5 True False 16877.040331430428 14152.375420715422 22372.21547913748 15424.428377670549 16692.387838342656 17520.920385159046 15276.658890132072 17703.76801436182 16258.82799712443 11190.970557815257 1.5080944270418335 1.264624488787709 1.9991309389616578 1.3782922846579058 1.4915942948920962 1.565630102826358 1.3650879350641807 1.5819689563921089 1.452852361028688 1.0 13.450047541710665 -12.281632819064185 0.35991727697500253 7.017545317631116e-14 1.533840235617761 0.40911131103597553 0.1860029289623707 77.14561615558644 2.752409706120541 59.40451898900595 0.13423394227552576 5.228380436355646e-13 12.281632819064185 1.5338402356176908 SPAGPAATPAQAQAAS(ph)TPRK ddPTM_PC-9_Lapatinib_30min_R1 1 SPAGPAATPAQAQAASTPRK 20 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 SPAGPAATPAQAQAAS(0.5)T(0.5)PRK 78.976 0.0007769999999999999 6831800.0 12843.0 11875.0 23504.0 12477.0 16134.0 16423.0 8665.2 9695.0 17226.0 11743.0 True False 12659.856464882241 11847.504167097832 21571.591848063752 13394.600202051852 15185.029840664438 15720.626573882846 9113.841656850773 10145.46509333757 15285.82648217827 13772.761903436065 0.9191951878383832 0.8602126610598042 1.5662502553450819 0.9725427837905287 1.1025406485010125 1.14142876237197 0.661729413515602 0.7366325770001478 1.1098591981296593 1.0 13.7495302770646 -7.235772995189767 24.513979104904976 0.8551079741486822 1.099457168985774 0.1927515024459895 0.21513486490913328 916.2240136376338 875087.0983633285 0.08325678465403079 0.06446508336832404 5.8106806120819016e-08 7.235772995189767 0.24434919483709172 SPAGPAATPAQAQAAST(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 SPAGPAATPAQAQAASTPR 19 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 SPAGPAAT(0.005)PAQAQAAS(0.075)T(0.921)PR;SPAGPAATPAQAQAAS(0.248)T(0.752)PR;SPAGPAATPAQAQAAS(0.039)T(0.96)PR;SPAGPAATPAQAQAAS(0.368)T(0.632)PR 196.11 4.811e-59 218365000.0 55566.5 60814.6 73896.7 91401.1 88743.2 91444.5 86195.8 98552.9 78762.3 83679.1 True False 73235.49114499993 80471.73015567924 72916.78147475388 70329.98852791806 76422.73849913527 85726.46095918099 93867.05921660949 83323.8138253455 82925.5143815777 80749.52017893585 0.9069464559382483 0.9965598554314496 0.9029995635042151 0.8709647855748397 0.9464172459450817 1.061634307785564 1.1624472691429744 1.0318799869114412 1.0269474567504546 1.0 16.301166066755066 -6.724181708978801 4.621057215163156 1.065901982202601 0.922528249186797 0.6329659538652451 0.05020118060911673 0.13069357957215424 6.2924335173882096 0.0179174517180222 0.017306868241727665 1.8872015780191335e-07 6.724181708978801 -0.14337373301580403 SPAGPAATPAQAQAAST(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SPAGPAATPAQAQAASTPR 19 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 SPAGPAATPAQAQAAS(0.243)T(0.757)PR;SPAGPAATPAQAQAAS(0.243)T(0.757)PR;SPAGPAATPAQAQAAS(0.381)T(0.619)PR;SPAGPAATPAQAQAAS(0.101)T(0.899)PR;SPAGPAATPAQAQAAS(0.2)T(0.8)PR;SPAGPAATPAQAQAAS(0.071)T(0.929)PR 203.64 6.916899999999999e-60 130825300.0 78987.7 103950.5 107435.3 93278.1 115063.0 78403.0 92097.8 82134.6 77448.6 66424.4 True False 92358.7575318126 114270.01865507859 109996.96500264398 88052.03046868026 92517.23113665669 74291.40865940665 83373.6296536697 79978.65377880202 78581.13925664376 78466.6179047388 1.1770452199678 1.4562883135068516 1.4018313512146543 1.1221591145368146 1.1790648508512986 0.9467899935434837 1.0625362973447918 1.0192697979655359 1.0014594913730575 1.0 16.259791397550636 -6.122603020835263 1.5704303995390396 1.0168392829361965 1.353696038696556 0.7078423973724324 0.08855197955857888 0.19952970866613234 0.9834561347002715 0.03054604831879353 0.04675271977626914 7.540445045369001e-07 6.122603020835263 0.33685675576035945 SPAGPAATPAQAQAAST(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 SPAGPAATPAQAQAASTPR 19 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 SPAGPAATPAQAQAAS(0.233)T(0.767)PR;SPAGPAATPAQAQAAS(0.224)T(0.776)PR;SPAGPAATPAQAQAAS(0.036)T(0.964)PR;SPAGPAATPAQAQAAS(0.311)T(0.689)PR 193.06 2.161e-14 194183000.0 39519.64 72675.0 78261.3 68414.8 82891.3 76774.1 65332.5 67317.4 75055.7 70023.1 True False 38956.08268658561 72506.72550263886 71826.95801135429 73446.25261708241 78015.79670456595 73490.65071216825 68715.09717562245 70445.21215825099 66602.13669444028 82126.49953508408 0.4743424218384438 0.8828663818998436 0.8745893033060557 0.8943063814098944 0.9499466937737672 0.8948469876129734 0.836698234609009 0.8577646990562054 0.8109701140493409 1.0 16.32556018717107 -4.761429793452675 9.582595865193424 0.8849494015457794 0.4722166874782871 0.8547051066105085 0.05127792367732304 0.026870620728867294 43.70064747443257 0.012629526807491942 0.07177077544705011 1.7320890116518382e-05 4.761429793452675 -0.4127327140674923 SPAGPAATPAQAQAAST(ph)PRK ddPTM_PC-9_AZD4547_30min_R2 2 SPAGPAATPAQAQAASTPRK 20 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 SPAGPAAT(0.005)PAQAQAAS(0.405)T(0.59)PRK;SPAGPAAT(0.012)PAQAQAAS(0.275)T(0.712)PRK 91.73299999999999 0.0015967000000000002 0.0 14389.0 10436.0 43470.0 77928.0 52630.0 32096.0 21430.2 56879.0 23174.0 31190.0 True False 18964.402690207316 13809.232912897038 42893.55939720656 59962.90357559808 45323.23295992798 30089.032046168773 23337.446284201633 48089.65749939189 24398.93032934134 30098.047593497155 0.6300874709994371 0.45880826223029153 1.425127635404296 1.992252267836582 1.505852923487313 0.9997004607258868 0.7753807356342879 1.5977666773901282 0.8106482738971036 1.0 14.87738228452328 -5.259253173946194 24.965653284427187 1.2925407222601644 0.5444478011071235 0.3811464681729868 0.3648998726748258 191.27402353054032 2184240.8240721794 0.10011744257162192 0.2396417861692437 5.504866941241249e-06 5.259253173946194 -0.7480929211530408 SPAGSQQQFGYSPGQQQTHPQGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 SPAGSQQQFGYSPGQQQTHPQGSPR 25 0 Q8TAP9 Q8TAP9 MPLKIP M-phase-specific PLK1-interacting protein 1 SPAGSQQQFGYSPGQQQT(0.262)HPQGS(0.738)PR;SPAGSQQQFGYSPGQQQT(0.054)HPQGS(0.946)PR 154.25 5.0292999999999996e-09 25089000.0 19152.6 17621.0 31507.0 59553.0 43145.0 38753.0 31385.0 37500.0 29460.0 37031.5 True False 25242.72840117205 23316.64365256407 31089.196593691893 45823.97593467812 37155.06148691037 36329.76878381039 34178.20419919869 31705.236664273205 31017.195456218 35735.03845651135 0.7063859307690916 0.6524868772966299 0.8699919724873577 1.2823261961910228 1.0397375542809937 1.016642778432233 0.9564339560119045 0.8872310772201263 0.8679771114270705 1.0 15.125051720389953 -5.481867180681849 5.596747765949149 1.0075029079295772 0.6933644535181407 0.5944464559495174 0.10760978685935353 0.14496307043525866 11.673744284765126 0.03143728972039316 0.06447453184880086 3.297105314005442e-06 5.481867180681849 -0.3141384544114365 SPAGSQQQFGYSPGQQQTHPQGS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPAGSQQQFGYSPGQQQTHPQGSPR 25 0 Q8TAP9 Q8TAP9 MPLKIP M-phase-specific PLK1-interacting protein 1 SPAGSQQQFGYSPGQQQT(0.188)HPQGS(0.812)PR;SPAGSQQQFGYSPGQQQT(0.25)HPQGS(0.75)PR 158.11 1.9481e-09 16157200.0 23713.0 24565.0 36629.0 30432.0 36609.0 36134.0 28388.0 32348.0 24139.2 22988.8 True False 27727.142546901316 27003.65085557074 37502.374276256065 28726.993701875188 29435.729249905406 34239.06942972844 25698.883128678146 31498.8992755391 24492.19013312028 27156.487460759326 1.0210135823702007 0.9943720039121616 1.380972938066691 1.0578317149220868 1.0839299188615443 1.260806261457905 0.9463257413467999 1.1599032946015013 0.9018909447884631 1.0 14.729009266692582 -7.280922122108535 24.886908371552607 1.0153552772137755 1.13244936990603 0.20588103839760818 0.1250655207171704 1487.4960736128683 1900092.3642853997 0.051994170416407345 0.03511404616885076 5.236943372820646e-08 7.280922122108535 0.11709409269225457 SPAGSQQQFGYSPGQQQTHPQGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 SPAGSQQQFGYSPGQQQTHPQGSPR 25 0 Q8TAP9 Q8TAP9 MPLKIP M-phase-specific PLK1-interacting protein 1 SPAGSQQQFGYSPGQQQT(0.143)HPQGS(0.857)PR;SPAGSQQQFGYSPGQQQT(0.189)HPQGS(0.811)PR 150.24 3.0901e-07 20815500.0 51256.0 44518.0 57577.0 41320.0 46270.0 48008.0 37810.0 35116.0 43464.0 42273.0 True False 50525.08004080081 44414.92130617779 52843.241313647326 44358.810639479256 43548.489570320045 45954.80975211399 39767.616794249145 36747.617557260695 38568.62662378942 49579.83172476819 1.019065177979626 0.8958263826456231 1.065821312323028 0.8946946590244131 0.8783508950185662 0.9268851497363337 0.8020926132829684 0.7411807640101971 0.7779095910993584 1.0 15.597465754438094 -6.531983339138083 1.0619833564220529 0.8162201279322973 0.98091061884579 0.33543800384319367 0.08258387101545599 0.5230842392427496 1.2605512484640935 0.039977983926190286 0.045745838573836246 2.937762351330459e-07 6.531983339138083 0.16469049091349275 SPALKS(ph)PLQSVVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPALKSPLQSVVVR 14 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.001)PALKS(0.997)PLQS(0.002)VVVR 113.28 0.0010831 11541000.0 17738.0 19491.0 20129.0 21825.0 22024.0 25645.0 25067.0 23082.0 18333.0 18719.0 True False 20740.693058530567 21425.93766846851 20608.95169965759 20602.216007604682 17708.55530060685 24300.131054557663 22692.47229063601 22476.121957400566 18601.0854423715 22112.606520477537 0.9379578585330274 0.968946724965547 0.9320001095561722 0.9316955008685137 0.8008352739514321 1.0989265798246965 1.0262233115585666 1.016439284829963 0.8411982289444635 1.0 14.432581472208295 -6.769811462049329 24.999543784589164 0.9994390166449879 0.9192749244451491 0.2398372133036576 0.07287329885516808 299.5615624210619 894502.9730344081 0.026063584837155783 0.023360921959141037 1.6989810619871474e-07 6.769811462049329 -0.08016409219983878 SPAPEQFQS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 SPAPEQFQSR 10 0 Q9P0V3;Q9P0V3-2 Q9P0V3 SH3BP4 SH3 domain-binding protein 4 1 SPAPEQFQS(1)R;SPAPEQFQS(1)R 96.23 0.0056113 16769500.0 4742.299999999999 11523.8 15128.1 18906.6 24853.0 24804.0 26922.0 29842.0 25346.9 22935.0 True False 6250.2527540322535 15248.642989808639 14927.491509475054 14547.975474058157 21402.58994400702 23253.001958909823 29318.005845175325 25230.604600939747 26686.685387278063 22132.052630870683 0.2824072786323555 0.6889845801531853 0.6744738844807184 0.6573260834273479 0.9670404413440542 1.0506482316274448 1.324685348176038 1.140002918922535 1.205793508282842 1.0 14.433849639231088 -6.204744398478131 0.9435101198865853 1.190399698798399 0.47949486190028257 0.8283828472327851 0.12458018685208065 0.22641202611459 0.4250673711655001 0.05813059144258217 0.09921765671592218 6.241020390830483e-07 6.204744398478131 -0.7109048368981163 down SPAPEQFQS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPAPEQFQSR 10 0 Q9P0V3;Q9P0V3-2 Q9P0V3 SH3BP4 SH3 domain-binding protein 4 1 SPAPEQFQS(1)R;SPAPEQFQS(1)R;SPAPEQFQS(1)R 88.163 0.010164 17968100.0 8633.400000000001 16341.0 28441.0 25922.5 39264.3 30564.8 26447.399999999998 22963.0 30990.5 30068.7 True False 10094.864102577403 17963.226486093285 29119.14130309315 24470.14636687891 31570.742276135945 28961.928081744754 23942.110809405473 22360.24558130963 31443.677434234116 35519.917286301774 0.284202916949654 0.5057226440395115 0.819797553817022 0.6889133825859387 0.8888180122061031 0.8153714956119534 0.6740474820485781 0.6295128843087943 0.8852407279214117 1.0 15.11634060169971 -5.004155754028635 2.342635200752754 0.7838643618030994 0.26018060937100634 0.7048500662702301 0.10870321723438953 0.2072526197083855 1.8994290367118267 0.02869705903721524 0.18377064622563127 9.90476659704161e-06 5.004155754028635 -0.523683752432093 down SPAPEQFQS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 SPAPEQFQSR 10 0 Q9P0V3;Q9P0V3-2 Q9P0V3 SH3BP4 SH3 domain-binding protein 4 1 SPAPEQFQS(1)R 110.15 0.0052068 0.0 26402.0 32562.0 22616.0 21717.0 33605.0 24811.0 20758.0 18769.0 23001.0 16130.0 True False 26025.50263846616 32486.604689603337 20756.599780284618 23314.14062578828 31628.419969972 23749.891367265867 21832.74767032595 19641.07625960318 20410.385168732304 18918.049008125996 1.3756969668112844 1.7172280648839184 1.0971850094779274 1.2323755275067743 1.6718647867116971 1.2554091258070226 1.1540697278534369 1.0382189120646963 1.0788842528088016 1.0 14.207475692780998 -7.225927350393151 2.5301256968657886 1.0554072051689019 1.4090364609308472 0.4674784114348697 0.17576544889484885 0.28405900769644876 3.5826431381709463 0.08302965601515729 0.05682484892765923 5.9439158125362806e-08 7.225927350393151 0.35362925576194537 SPAPGAPT(ph)RSPSTPAK ddPTM_PC-9_Lapatinib_30min_R1 1 SPAPGAPTRSPSTPAK 16 1 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 S(0.002)PAPGAPT(0.576)RS(0.413)PS(0.008)T(0.001)PAK 90.714 0.035486000000000004 6537200.0 16830.0 12295.0 14818.0 12500.0 14811.0 12125.0 9576.4 9580.7 13937.0 9104.6 True False 16590.001113755992 12266.531682902552 13599.721239134136 13419.291698777615 13939.846099546361 11606.442014755496 10072.219134314935 10025.854298064904 12367.268296883709 10678.317978883082 1.5536155737789008 1.1487325725980668 1.2735827183670947 1.2566859055250976 1.3054346318505514 1.0869166883499655 0.9432402326127824 0.9388982719836159 1.1581663255711818 1.0 13.382396794867676 -6.865508180201589 3.66583818350099 1.0056455710002843 1.2950052224205149 0.6221295664944458 0.1107931202301882 0.15812354065115175 4.075854392964616 0.039693339088197534 0.035011942260330046 1.3629873332678786e-07 6.865508180201589 0.28935965142023057 SPAPGAPTRS(ph)PSTPAK ddPTM_PC-9_AZD4547_30min_R2 1 SPAPGAPTRSPSTPAK 16 1 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 SPAPGAPT(0.185)RS(0.804)PS(0.005)T(0.005)PAK 53.038000000000004 0.036692 53874000.0 47365.0 47995.0 57540.0 70719.0 58928.0 46268.0 44809.0 57787.0 44843.0 56037.0 True False 62426.084746797475 63508.44515662068 56776.98200403186 54415.82714765839 50746.86437132124 43374.85464581683 48796.91419346485 48857.346963156124 47213.30943120104 54075.161686335356 1.1544317723708697 1.1744476239387571 1.049964165310656 1.0062998509981176 0.9384505341968276 0.8021215895278133 0.9023905370179539 0.9035081068560584 0.8731052845493704 1.0 15.722678453444063 -5.76228566039798 1.2786271412603545 0.8908066166227739 1.1733222696306902 0.8135531325395466 0.04940016512817179 0.18586715433764234 0.6017172550533445 0.016927706212338176 0.04290922988458986 1.7286789338650432e-06 5.76228566039798 0.28251565300791626 SPAPGAPTRS(ph)PSTPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPAPGAPTRSPSTPAK 16 1 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 S(0.001)PAPGAPT(0.05)RS(0.809)PS(0.071)T(0.071)PAK;S(0.001)PAPGAPT(0.189)RS(0.786)PS(0.012)T(0.012)PAK;SPAPGAPT(0.024)RS(0.919)PS(0.028)T(0.028)PAK 59.733000000000004 0.022798 106120000.0 124246.0 102806.0 105482.0 128206.0 129825.0 128331.0 120375.0 136370.0 142026.0 97458.0 True False 145278.39382964227 113011.90025881535 107997.09092271276 121023.03346945984 104386.7232065605 121601.09644618594 108972.20856047029 132790.4319959584 144102.86156320575 115126.36392289671 1.2619037801535988 0.9816335408152257 0.9380743666588948 1.051219106950275 0.9067143237188587 1.0562402242428637 0.9465443435132892 1.153431998294429 1.25169298024313 1.0 16.812858722724265 -7.779759408785032 24.60154951767333 1.15192199772826 1.0138796455465768 0.18013578796707175 0.10979351482519847 294.7928058177803 395863.9154818598 0.0576910127757721 0.027803273279092107 1.6605065429958093e-08 7.779759408785032 -0.13804235218168315 SPAPGAPTRS(ph)PSTPAK ddPTM_PC-9_Lapatinib_30min_R1 2 SPAPGAPTRSPSTPAK 16 1 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 SPAPGAPT(0.25)RS(0.74)PS(0.01)TPAK;SPAPGAPT(0.152)RS(0.494)PS(0.339)T(0.014)PAK 154.31 0.00016782 19209100.0 23236.0 20710.9 21964.0 18715.5 18314.6 20092.6 17433.9 17279.699999999997 21725.0 14703.6 True False 22904.650379039478 20662.9451835239 20158.20470349182 20091.900303077775 17237.371235888986 19233.286336138266 18336.54203727215 18082.577944646226 19278.10172560799 17245.09766868453 1.3281832796245718 1.198192412736859 1.1689237771089704 1.1650789510785298 0.9995519635235481 1.1152900787024302 1.0632901239271946 1.0485633825943752 1.1178888108366705 1.0 14.073898679164557 -1.522878745289372 0.4147578763891986 1.0500898893901807 6.033775011172916 0.7854345319330881 0.04421943481854725 33.73622430235792 0.4364496334106611 0.029725688047425154 138.95566993481432 0.029999999999375925 1.522878745289372 4.983685121782735 SPART(ph)PPSEEDSAEAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPARTPPSEEDSAEAER 17 1 O43765;K7EMD6 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 S(0.164)PART(0.836)PPSEEDSAEAER 57.148 0.033527999999999995 8218000.0 8645.2 1139.4 6561.4 8779.7 11661.0 9252.6 11917.0 9467.1 7578.8 6117.0 True False 10108.661609516774 1252.512101967731 6717.848660248066 8287.801873171447 9376.110759188914 8767.377367728608 10788.135488391485 9218.598656221591 7689.625612319047 7225.963677854641 1.3989361225958992 0.1733349568039341 0.929682041003916 1.1469476242415961 1.2975585232906461 1.2133160030402488 1.492968407999864 1.275760447630503 1.0641661036693815 1.0 12.81897428757655 -5.70725905837799 3.417492024076112 1.2448665154526357 0.7419581372963637 0.24471916275059835 0.30451507294600694 0.25913212608729036 6.125732472528633 0.0815400958983131 0.14566512172263776 1.9621894738862475e-06 5.70725905837799 -0.502908378156272 SPART(ph)PPSEEDSAEAER ddPTM_PC-9_Lapatinib_30min_R1 1 SPARTPPSEEDSAEAER 17 1 O43765;K7EMD6 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 S(0.293)PART(0.707)PPSEEDSAEAER 66.63600000000001 0.014319 5134600.0 5182.7 2358.5 4574.3 5991.7 6782.8 4762.5 4472.5 4433.7 6815.5 6274.1 True False 5108.79374760922 2353.0390381558086 4198.218711308628 6432.349605725266 6383.849039497875 4558.818976929739 4704.064165889427 4639.7058880176155 6047.866619603277 7358.569825287251 0.6942644928166857 0.31976852758395274 0.5705210130481769 0.8741304028428066 0.8675393712457806 0.6195251367002935 0.6392633728532703 0.6305173421163397 0.8218807136707698 1.0 12.845209683218886 -14.522878745280291 0.0491415530129219 2.314585221582087 1.1987465592917537e-12 0.364777400222423 0.1468470540192879 713.7900155107559 2.5866591920671755 124.97837470302467 28.545718054622558 3.00000000000032e-15 14.522878745280291 -2.3145852215808884 SPASDTYIVFGEAK ddPTM_PC-9_Lapatinib_30min_R1 1 SPASDTYIVFGEAK 14 0 E9PAV3;F8VZJ2;F8W0W4;H0YHX9;Q13765;E9PAV3-2;F8W1N5;F8VNW4 E9PAV3 NACA Nascent polypeptide-associated complex subunit alpha, muscle-specific form;Nascent polypeptide-associated complex subunit alpha 0 155.02 0.0014428 8642800.0 27375.0 21119.0 28342.0 25553.0 28867.0 23337.0 28394.0 22745.0 26533.0 26762.0 False True 26984.627480039835 21070.100253047494 26011.830163283797 27432.252862309128 27169.099814705605 22338.930911204065 29864.10238709099 23801.815734704807 23544.574135123432 31387.776041876506 0.8597177271826414 0.6712836304469766 0.8287248554526353 0.873978864437861 0.8655949302829711 0.7117079872559375 0.9514564634094278 0.758314819850544 0.7501192216903504 1.0 14.937915190979163 -11.046176150950767 3.018603163604172 1.006978689802721 0.8080516777781963 0.33774731637424227 0.08070739985941244 117123937.03779706 128191127.1133765 6669438.731045768 0.019956261955305574 8.991328169939454e-12 11.046176150950767 -0.19892701202452479 SPAVATSTAAPPPPS(ph)SPLPSK ddPTM_PC-9_AZD4547_30min_R2 3 SPAVATSTAAPPPPSSPLPSK 21 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 SPAVATSTAAPPPPS(0.924)S(0.076)PLPSK;SPAVATSTAAPPPPS(0.92)S(0.08)PLPSK;SPAVATSTAAPPPPS(0.723)S(0.277)PLPSK 297.29 6.525999999999998e-132 504662000.0 867080.0 878369.0 1233620.0 1686050.0 1586150.0 1360820.0 1141337.0 1636250.0 1112881.0 1434870.0 True False 1142793.4036156056 1162284.6018080178 1217261.3927670124 1297357.2217128284 1365940.4514419462 1275727.7102775206 1242913.7819372576 1383405.159784457 1171705.6176684094 1384635.6380404348 0.825338718879799 0.8394154894445063 0.8791203687994814 0.9369665102285504 0.9864981182883994 0.9213454249111752 0.8976468233161 0.9991113342585063 0.8462194569299339 1.0 20.401074955454746 -5.542509327764921 2.3878925303501104 0.9406628320470956 0.8314060216260873 0.49188856611329823 0.04506702465550447 0.24267559102118907 2.7495549027737 0.012318412454580976 0.028370384602132818 2.8674157886426036e-06 5.542509327764921 -0.10925681042100821 SPAVATSTAAPPPPS(ph)SPLPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPAVATSTAAPPPPSSPLPSK 21 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 SPAVATSTAAPPPPS(0.476)S(0.476)PLPS(0.048)K 88.781 0.0002459 3933700.0 8222.7 9076.5 14587.0 13528.0 17631.0 17694.0 19662.0 15720.0 14501.0 13339.0 True False 9614.640704272153 9977.554935501237 14934.809401505563 12770.070018367758 14176.332115192503 16766.0954914932 17799.4730194473 15307.366656716778 14713.049691803257 15757.255108534095 0.6101723071720077 0.6332038712819605 0.9478052680264664 0.8104247808650071 0.8996701530531566 1.0640238655787657 1.1296049278155778 0.9714488057267248 0.9337317693000161 1.0 13.943728620802977 -5.030587469137779 0.6791732262205938 1.018097963802295 0.3936522772485499 0.7572937274448059 0.07964443797232684 1.2129556630122837 0.5296766470709303 0.03946745935451735 0.555628761349914 9.319927433154629e-06 5.030587469137779 -0.624445686553745 SPAVATSTAAPPPPS(ph)SPLPSK ddPTM_PC-9_Lapatinib_30min_R1 3 SPAVATSTAAPPPPSSPLPSK 21 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 SPAVATSTAAPPPPS(0.483)S(0.483)PLPS(0.035)K;SPAVATSTAAPPPPS(0.585)S(0.414)PLPS(0.001)K;SPAVATSTAAPPPPS(0.493)S(0.493)PLPS(0.013)K 145.52 1.9313e-06 33972000.0 169107.0 147650.0 173267.0 161986.0 171565.0 190242.0 172993.0 156461.0 197363.0 151939.0 True False 166695.50316957387 147308.12549658926 159021.65608996208 173898.9908094549 161473.88400976776 182105.7931357623 181949.73107875034 163730.74924896206 175133.90061547395 178201.4537040087 0.9354329030696567 0.8266381807483287 0.8923701394383454 0.9758561852043017 0.9061311266179383 1.0219096946214519 1.0210339326466298 0.9187958114018399 0.9827860377972566 1.0 17.443149580337106 -5.714770971431799 4.547833018772282 0.9731205401270232 0.8763362220726254 0.474096178763299 0.043556072743495246 0.1719009027682915 7.5864227917248925 0.012116843534928631 0.020982486892610248 1.928541676500463e-06 5.714770971431799 -0.0967843180543978 SPAVATSTAAPPPPSS(ph)PLPSK ddPTM_PC-9_AZD4547_30min_R2 1 SPAVATSTAAPPPPSSPLPSK 21 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 SPAVATSTAAPPPPS(0.233)S(0.719)PLPS(0.048)K 113.67 2.3494999999999997e-06 79704000.0 277260.0 277260.0 447560.0 605590.0 522930.0 480570.0 402110.0 569240.0 384840.0 510090.0 True False 365422.91263373947 366878.87288518954 441625.06196949055 465980.58177223225 450330.19592884596 450519.8819300627 437897.011009711 481277.0378338894 405181.85673356813 492231.90435931244 0.7423795763693393 0.745337450977945 0.8971890242350471 0.9466687909609418 0.9148740500983868 0.9152594091121705 0.8896152547845846 0.9777445012637248 0.823152366080276 1.0 18.908978644563753 -5.290503074370022 4.076974098430239 0.9207824543384447 0.7402320205553906 0.7076489948856832 0.045648998348764895 0.09888444474577333 3.784244089612849 0.011124870564251219 0.027269485601511118 5.122676439097776e-06 5.290503074370022 -0.18055043378305413 SPAVATSTAAPPPPSS(ph)PLPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SPAVATSTAAPPPPSSPLPSK 21 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 SPAVATSTAAPPPPS(0.189)S(0.811)PLPSK;SPAVATSTAAPPPPS(0.23)S(0.77)PLPSK;SPAVATSTAAPPPPS(0.336)S(0.664)PLPSK;SPAVATSTAAPPPPS(0.318)S(0.681)PLPSK;SPAVATSTAAPPPPS(0.333)S(0.666)PLPS(0.001)K;SPAVATSTAAPPPPS(0.289)S(0.711)PLPSK 293.63 1.1372999999999996e-131 605449000.0 307166.0 335280.0 459774.0 477306.0 603805.0 577172.0 629734.0 644442.0 590327.0 468998.0 True False 359163.13699496083 368564.38261167426 470736.755862605 450564.0922669308 485493.74470045994 546904.0842667631 570081.0366406572 627526.080342741 598959.4155860394 554023.6248138751 0.6482812661926143 0.6652502999948674 0.849669102144786 0.8132579046936823 0.8763051302434299 0.9871493917799916 1.0289832619180757 1.1326702549075578 1.0811080769114505 1.0 19.079587971785486 -6.058886320102924 0.5942379780180542 1.0907115355960422 0.6068488412363628 0.8992212425050862 0.05015136222348748 0.3319203079865417 0.2240659778108613 0.035391518387106226 0.09185216295081904 8.731999052194542e-07 6.058886320102924 -0.4838626943596793 SPAVATSTAAPPPPSS(ph)PLPSK ddPTM_PC-9_Lapatinib_30min_R1 3 SPAVATSTAAPPPPSSPLPSK 21 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 SPAVATSTAAPPPPS(0.234)S(0.766)PLPSK;SPAVATSTAAPPPPS(0.356)S(0.644)PLPSK;SPAVATSTAAPPPPS(0.228)S(0.772)PLPSK 359.08 3.6290999999999977e-259 683894000.0 231608.0 205492.0 239514.0 192211.0 236102.0 235147.0 216811.0 218114.0 257590.0 196148.0 True False 228305.22744829464 205016.1958993908 219822.08347077682 206346.83813709972 222214.94455439175 225090.3109644299 228036.41271562944 228248.3727043045 228577.50165704775 230051.92044921895 0.9924073965672029 0.8911735902880478 0.9555324860645958 0.8969576856136185 0.9659338818840371 0.9784326534849151 0.9912389006375002 0.9921602578174844 0.9935909303026372 1.0 17.811599974394596 -6.596808894500648 2.890729650273323 0.9912309872227526 0.9323026548832992 0.48774108245046055 0.02731519324935776 0.2099182015932573 3.5567178198302716 0.008962121461746984 0.009131720258797259 2.5304112252368324e-07 6.596808894500648 -0.05892833233945338 SPCETIS(ph)SPSSTLESK ddPTM_PC-9_AZD4547_30min_R2 2 SPCETISSPSSTLESK 16 0 Q9C0D5 Q9C0D5 TANC1 Protein TANC1 1 SPCETIS(0.987)S(0.011)PS(0.001)STLESK;SPCETIS(0.992)S(0.007)PS(0.001)STLESK 182.35 1.257e-06 16123700.0 97440.0 109954.0 152816.0 195076.0 211230.0 194615.0 165029.0 180857.0 164308.0 167255.0 True False 128423.8931220934 145494.48023233822 150789.55999179944 150104.24209415604 181904.36059520426 182445.69328468113 179716.26129646518 152909.70633041233 172992.98543856974 161399.45335845958 0.7956897650506336 0.901455842661392 0.9342631393980243 0.9300170413885016 1.1270444652077252 1.1303984585342985 1.1134874223974287 0.9473991587245839 1.0718312970636992 1.0 17.30027616681722 SPCETIS(ph)SPSSTLESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPCETISSPSSTLESK 16 0 Q9C0D5 Q9C0D5 TANC1 Protein TANC1 1 SPCET(0.001)IS(0.982)S(0.017)PSSTLESK 207.85 3.1409999999999996e-63 0.0 23572.0 23871.0 26951.0 36413.0 41132.0 31415.0 37620.0 32864.0 33802.0 27923.0 True False 27562.27403177825 26240.755122056966 27593.614052236688 34372.8976625388 33072.47986853258 29767.542097053178 34056.36125478624 32001.354822286285 34296.290302898655 32985.21886165361 0.8355946991705516 0.7955307264176652 0.8365448223329863 1.0420697163388664 1.0026454578714472 0.9024509499816876 1.0324734056677087 0.970172578102518 1.0397472409306707 1.0 15.009532056983565 -5.7030832266616365 6.786928950248708 0.9947216045632462 0.8175451393897485 0.8027913299375155 0.03994543256363819 0.08771438371073646 7.976799846372193 0.01082946127289162 0.018747723671858906 1.9811473293428307e-06 5.7030832266616365 -0.17717646517349772 SPCETIS(ph)SPSSTLESK ddPTM_PC-9_Lapatinib_30min_R1 2 SPCETISSPSSTLESK 16 0 Q9C0D5 Q9C0D5 TANC1 Protein TANC1 1 SPCETIS(0.997)S(0.003)PSSTLESK;SPCETIS(0.876)S(0.119)PS(0.004)STLESK 259.96 9.305499999999998e-58 12859200.0 75166.0 96956.0 99069.0 89609.0 93609.0 94429.0 73911.0 84125.0 107002.0 79826.0 True False 74094.11905624367 96731.50433895884 90923.92923739896 96199.14478686097 88103.10266237504 90390.49179475027 77737.74993069946 88033.75461341147 94950.30797898758 93623.81773854115 0.7914024534137546 1.0331933334431669 0.9711623754899416 1.0275071783070395 0.9410330062422411 0.9654647073587573 0.8303202305613516 0.9402922967663977 1.0141682989701493 1.0 16.514587975192796 SPDASSAFSPAS(ph)PATPNGTK ddPTM_PC-9_AZD4547_30min_R2 1 SPDASSAFSPASPATPNGTK 20 0 Q53GS7-2;Q53GS7 Q53GS7-2 GLE1 Nucleoporin GLE1 1 SPDAS(0.001)S(0.009)AFS(0.041)PAS(0.95)PATPNGTK 205.92 1.8443999999999995e-72 0.0 25976.0 22692.0 32711.0 39548.0 40284.0 25027.0 26957.0 37545.0 26526.0 28491.0 True False 34235.827665635225 30026.74523375428 32277.23076701227 30430.819610509127 34691.261952455636 23462.05773365731 29356.120777371354 31743.28294827031 27928.1102060977 27493.538761985463 1.2452317601607594 1.0921382472332521 1.1739933169913028 1.106835314069681 1.2617968990016761 0.8533662376739088 1.0677461723465453 1.1545724696655217 1.0158063117256155 1.0 14.746804991230864 -6.736767375305787 24.99991597638729 1.0310493250325556 1.1673862686008916 0.45275654631391715 0.08585922634352348 249.35386688784374 252667.4670053466 0.02839055420869839 0.0283780225168478 1.8332961427843968e-07 6.736767375305787 0.13633694356833592 SPDASSAFSPAS(ph)PATPNGTK ddPTM_PC-9_Lapatinib_30min_R1 1 SPDASSAFSPASPATPNGTK 20 0 Q53GS7-2;Q53GS7 Q53GS7-2 GLE1 Nucleoporin GLE1 1 SPDASSAFS(0.042)PAS(0.939)PAT(0.019)PNGTK 247.28 1.7658e-54 8350200.0 41731.0 33780.0 28390.0 30956.0 29533.0 34179.0 30567.0 25623.0 32722.0 25213.0 True False 41135.90828747184 33701.784485437 26055.883788569176 33232.60750618877 27795.92700411199 32717.243845140474 32149.609694520346 26813.538121360365 29036.503782064192 29571.033455789253 1.3910879492586175 1.1396890993283513 0.8811286162022214 1.123822999147927 0.9399714435299946 1.1063950096318083 1.0871993954011192 0.9067501195535984 0.9819238757913477 1.0 14.851897043551771 -4.859823419184062 3.2412627778649266 1.0084184242935867 1.4142327076693466 0.6908460337088079 0.07909157946522999 0.15664260744792735 2.719274666313691 0.019714193248973992 0.14465607051436996 1.3809456324073218e-05 4.859823419184062 0.40581428337575987 SPDEATAADQES(ph)EDDLSASR ddPTM_PC-9_Lapatinib_30min_R1 1 SPDEATAADQESEDDLSASR 20 0 C9JME2;Q9Y4F1;Q9Y4F1-2;M0QXT1 C9JME2 FARP1 FERM, RhoGEF and pleckstrin domain-containing protein 1 1 SPDEATAADQES(1)EDDLSASR 269.98 1.7073999999999997e-79 4494300.0 5791.1 12066.0 7490.9 7367.6 9146.5 7338.5 7127.4 6590.0 8875.8 4587.4 True False 5708.517852042328 12038.061918332829 6875.027117710203 7909.437881593115 8608.520852710883 7024.649461879034 7496.421897363959 6896.195457977787 7876.113937682456 5380.325977673728 1.0609985111925317 2.237422410516785 1.2778086581071308 1.4700666677844845 1.599999867746474 1.3056178177732376 1.393302548669209 1.2817430554569242 1.4638730014436454 1.0 12.393477868619902 -11.58596120663928 0.12445175683928236 0.243063094341003 1.7616922612747112 0.19030765371722336 0.2932711997734065 86.52544124178885 1.5020885872819028 21.90153339951627 3.0035422834184136 2.594411097576653e-12 11.58596120663928 1.5186291669337082 SPDEEDYDYES(ph)YEK ddPTM_PC-9_Lapatinib_30min_R1 1 SPDEEDYDYESYEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 SPDEEDYDYES(1)YEK 127.36 0.00059909 0.0 2614.6 4108.7 3239.9 2482.8 4308.2 2809.6 2995.8 3654.3 2853.4 2784.5 True False 2577.315324541084 4099.1865575877755 2973.527928375671 2665.3933943780034 4054.800146247088 2689.4399574974905 3150.9078654380237 3824.092118678031 2532.0200443659287 3265.797114886971 0.7891841513339951 1.2551871452460537 0.9105060185217857 0.8161540048608478 1.2415958504475022 0.8235171576451624 0.9648204571786684 1.1709521394473956 0.7753145573017514 1.0 11.673219452035005 -8.283195281630334 24.98288566011047 0.8876573596146017 0.9975844036388386 0.06004732149061465 0.1721923678294263 2806.7033826927 3222981.3059185636 0.1554225497931166 0.04026897582387715 5.209604072448843e-09 8.283195281630334 0.10992704402423692 SPDEEDYDYESYEK ddPTM_PC-9_Lapatinib_30min_R1 3 SPDEEDYDYESYEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 0 ;; 203.61 3.3559e-48 4746600.0 29487.8 32378.7 27910.0 36386.0 32862.2 33119.9 36572.1 34103.2 31450.3 30589.5 False True 29067.298564599765 32303.729109491385 25615.3475357156 39061.94782013779 30929.310005571046 31703.439083257796 38465.62438934037 35687.75917185247 27908.036027658858 35876.85431705333 0.8101964098559002 0.9004058389293196 0.7139797516623375 1.0887785053543697 0.8620964851667452 0.8836738807445617 1.072157108575055 0.9947293276180299 0.7778841417095295 1.0 15.130765779836196 -5.752686430130427 24.999991284306954 0.9521089702622975 0.8174152217500109 0.3122059115586925 0.09898413372127862 251.54989880010075 718464.1690219458 0.026656073089854918 0.04528146020116087 1.7673133980637893e-06 5.752686430130427 -0.13469374851228655 SPDKPGGS(ph)PSASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPDKPGGSPSASR 13 1 Q9Y3T9 Q9Y3T9 NOC2L Nucleolar complex protein 2 homolog 1 S(0.176)PDKPGGS(0.705)PS(0.062)AS(0.057)R;S(0.393)PDKPGGS(0.568)PS(0.035)AS(0.004)R 98.676 0.013026 22903000.0 21479.0 25600.0 20402.5 23938.8 23709.1 20464.7 25271.0 21239.9 18723.7 16288.400000000001 True False 25114.970470412583 28141.39881549404 20888.97297691212 22597.58664663676 19063.472052198413 19391.495105954626 22877.147933803924 20682.37513053428 18997.498690739707 19241.35798109655 1.3052597688316228 1.4625474378233196 1.0856288312620268 1.174427848015587 0.9907550221209491 1.0078028341349698 1.188957034959763 1.074891655300704 0.9873262952336098 1.0 14.231923002121919 -5.272712248775807 23.8342881181987 1.0702215056189675 1.3839035918189388 0.7330794025586436 0.07720083062254116 168.89024826201214 357086.6182995843 0.02018960636066938 0.04271461552400907 5.336883851781595e-06 5.272712248775807 0.3136820861999714 SPDKPGGS(ph)PSASR ddPTM_PC-9_Lapatinib_30min_R1 1 SPDKPGGSPSASR 13 1 Q9Y3T9 Q9Y3T9 NOC2L Nucleolar complex protein 2 homolog 1 S(0.001)PDKPGGS(0.606)PS(0.377)AS(0.017)R 104.78 0.006282 8636400.0 10625.0 9035.8 11348.0 9947.9 10018.0 7932.2 7792.6 8507.4 9572.1 8754.7 True False 10473.48555161364 9014.878160257902 10415.011244546775 10679.501751221578 9428.760936145798 7592.958296861325 8196.062698515369 8902.684861790623 8493.989299318395 10267.93823009552 1.0200183636589921 0.8779638091155558 1.0143235195961913 1.0400823916061122 0.9182720741842721 0.739482272556551 0.7982189330368734 0.8670372437279265 0.8272341641501457 1.0 13.325858901630841 -6.527800179183105 24.615144311043633 0.8343848839170793 0.9817378851531794 0.44087346339053834 0.07453892715520627 98.91580963450569 494733.0494808491 0.02395338183170205 0.024039526760392647 2.966195835463217e-07 6.527800179183105 0.14735300123610007 SPDKPGGSPS(ph)ASR ddPTM_PC-9_AZD4547_30min_R2 2 SPDKPGGSPSASR 13 1 Q9Y3T9 Q9Y3T9 NOC2L Nucleolar complex protein 2 homolog 1 S(0.047)PDKPGGS(0.135)PS(0.814)AS(0.005)R;SPDKPGGS(0.041)PS(0.957)AS(0.002)R 140.77 0.00035838 22732200.0 13983.0 16589.2 18764.8 19718.3 17478.8 17421.0 18202.4 19585.2 14958.7 16262.6 True False 18429.303135531925 21951.334480512793 18515.966491297488 15172.550579698142 15052.170326049576 16331.662116036445 19822.378337278784 16558.757363123284 15749.386343208698 15693.251323950202 1.1743457588935766 1.3987754371212955 1.1798680916451907 0.9668200850478068 0.9591492556470919 1.0406805944101547 1.2631148210203533 1.0551514801685609 1.003577016521288 1.0 13.937856660026263 -5.538450590951866 6.083586847041922 1.0502660861947042 1.2882270489566774 0.5227777705232136 0.09522465128299996 0.12208131621682293 16.814776770396637 0.027127545150805572 0.04963001363591239 2.8943390830596938e-06 5.538450590951866 0.2379609627619732 SPDVGLYGVIPECGETYHSDLAEAK ddPTM_PC-9_Lapatinib_30min_R1 1 SPDVGLYGVIPECGETYHSDLAEAK 25 0 P46940;H0YLE8;A0A0J9YXZ5 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 0 110.14 2.4371e-07 2918900.0 10354.0 13452.0 14531.0 10049.0 13852.0 10272.0 12669.0 13015.0 12036.0 12701.0 False True 10206.350061308942 13420.852720488425 13336.31727128209 10788.036982481291 13037.252594079819 9832.690505201523 13324.938830106916 13619.724413593449 10680.378935301163 14896.350926981297 0.6851577350277441 0.900949016727288 0.8952741068368921 0.7242066889644266 0.875197735202777 0.6600737693009016 0.8945102659988943 0.9142993797846468 0.716979546712754 1.0 13.86267134484747 -11.642147409625109 2.356881194314655 1.356003733665131 0.8136604613920277 0.2637984708590846 0.09601187518395221 13411381.91984794 3657085.8192379586 25556221.090830263 0.023108401975653708 2.279568202327163e-12 11.642147409625109 -0.5423432722731032 SPEDLER ddPTM_PC-9_AZD4547_30min_R2 1 SPEDLER 7 0 P06744-2;P06744;A0A2U3TZU2;Q8N196 P06744-2 GPI;SIX5 Glucose-6-phosphate isomerase;Homeobox protein SIX5 0 124.59 0.021338 17641000.0 80169.0 85628.0 102330.0 142000.0 125830.0 96461.0 96691.0 108530.0 89349.0 89256.0 False True 105661.07438120974 113305.57645319556 100973.03733876588 109264.09387813034 108360.67648390152 90429.27842115793 105296.31168471322 91759.18227129514 94071.80573040117 86131.17460741193 1.2267460052973338 1.3155001887486761 1.1723169665223252 1.2685777754240417 1.2580889205077281 1.0499018367430477 1.2225110381305777 1.065342283900525 1.092192300397421 1.0 16.394247885594908 -7.4881723314972115 0.41876469758520524 0.9976799952908563 1.279406221742543 0.6262811617910607 0.06260587661629789 0.6986966260247611 0.3014046720260737 0.06687385057240712 0.06464738759657589 3.249583257559413e-08 7.4881723314972115 0.28172622645168677 SPEEGAETPVYLALLPPDAEGPHGQFVSEK ddPTM_PC-9_Lapatinib_30min_R1 2 SPEEGAETPVYLALLPPDAEGPHGQFVSEK 30 0 P16152 P16152 CBR1 Carbonyl reductase [NADPH] 1 0 ; 144.0 1.9589e-17 8614600.0 46801.0 44343.0 58571.0 48269.0 52990.0 49409.0 52949.0 45080.0 52917.0 53219.0 False True 46133.60915774776 44240.32650792577 53755.51847059828 51818.86328066372 49873.23238234837 47295.8922480045 55690.44013855326 47174.581372631015 46956.9302192864 62417.833240140004 0.7391094301568915 0.7087770307200516 0.8612205147170807 0.8301932411094937 0.7990221671180283 0.7577304400497709 0.8922200154608947 0.7557869109479712 0.7522999082430352 1.0 15.929670656256086 -11.375718071412427 2.4126593665670324 1.092264439963515 0.7910008592619132 0.5720894466579003 0.05484039567759882 16221464.629862847 9400347.627749616 8609166.50797814 0.014832949857452909 4.2099983787168035e-12 11.375718071412427 -0.30126358070160186 SPEKIEEVLSPEGS(ph)PSKSPSK ddPTM_PC-9_Lapatinib_30min_R1 1 SPEKIEEVLSPEGSPSKSPSK 21 2 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 SPEKIEEVLS(0.017)PEGS(0.318)PS(0.318)KS(0.318)PS(0.03)K 61.757 0.0025909 21024000.0 67690.0 35529.0 45089.0 34364.0 30606.0 35203.0 28759.0 25332.0 41067.0 23762.0 True False 66724.72818717426 35446.73478339527 41381.956468573255 36891.24319494348 28805.815253711153 33697.44975220105 30248.000301132273 26509.01719901263 36441.60200531844 27869.230039125225 2.3942078088809895 1.2718950158878481 1.4848618498063169 1.323726674298227 1.0336064259138509 1.2091274034084785 1.0853547176821006 0.9511930240554543 1.307592709025638 1.0 14.766385524291845 -2.2427121089691218 0.9717262837263135 1.133828431437712 199.99999995861688 0.839029682184283 0.1589453401094098 104.76154847229891 0.8052580558985114 0.050116562245862445 45545.0840531087 0.005718575917900123 2.2427121089691218 198.86617152717918 up SPEKIEEVLSPEGSPS(ph)KSPSK ddPTM_PC-9_AZD4547_30min_R2 1 SPEKIEEVLSPEGSPSKSPSK 21 2 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 SPEKIEEVLS(0.001)PEGS(0.067)PS(0.404)KS(0.404)PS(0.124)K 47.32 0.019781 23272000.0 44619.0 31413.0 47357.0 86065.0 65301.0 72509.0 54691.0 56321.0 54867.0 63336.0 True False 58806.913867145755 41566.63793530419 46729.01523748586 66224.04394099486 56235.0833273087 67975.00076756123 59558.39304949426 47617.88357782747 57767.15760679947 61118.62591797805 0.9621766357454657 0.6800977167105676 0.7645625950458502 1.0835329320045306 0.9200973104790816 1.1121814299095094 0.9744720558577733 0.7791059249553689 0.9451645343650837 1.0 15.89932448830919 -5.741971288493401 24.917725863387883 0.9678966467948594 0.7900607714881008 0.34412825590287455 0.10773723612119632 265.0462521546961 339236.945569674 0.02992609614408688 0.05173640921352875 1.8114598455161125e-06 5.741971288493401 -0.1778358753067586 SPEKIEEVLSPEGSPSKS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 1 SPEKIEEVLSPEGSPSKSPSK 21 2 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 SPEKIEEVLSPEGS(0.012)PS(0.249)KS(0.719)PS(0.02)K 91.926 0.00013112 28059000.0 147870.0 126970.0 152440.0 259150.0 230030.0 183340.0 147320.0 155470.0 169250.0 211890.0 True False 194889.58411293037 168010.56946632217 150418.5459974735 199406.97132758776 198094.30510682586 171875.72081706673 160431.19460334402 131445.6838451882 178196.20946927677 204471.79559429645 0.9531367568152106 0.8216809021410514 0.7356444714552567 0.9752297168810603 0.968809925745825 0.8405840048379809 0.7846128319901109 0.6428548419753534 0.8714953030629491 1.0 17.641542329034245 -6.999363035806382 24.849171063124025 0.7974957466849568 0.8852727169609685 0.05654732007048191 0.10801503210772075 45.19329202290367 1762981.6509698606 0.03877286284169082 0.03389201033806515 1.0014677403350355e-07 6.999363035806382 0.08777697027601172 SPEPDT(ph)LPLAAGSDHPLPR ddPTM_PC-9_Lapatinib_30min_R1 1 SPEPDTLPLAAGSDHPLPR 19 0 H3BVB1;H3BME1;H7C112;H3BPZ0;Q6PCT2-2;Q6PCT2-3;Q6PCT2 H3BVB1 FBXL19 F-box/LRR-repeat protein 19 1 S(0.376)PEPDT(0.624)LPLAAGSDHPLPR 82.12100000000001 0.037822 0.0 6509.8 7447.8 8827.4 8354.0 12399.0 11533.0 10036.0 9707.8 11141.0 9299.9 True False 6416.969058248887 7430.555076691468 8101.645246749402 8968.381028127054 11669.715197371912 11039.760474736093 10555.614973474858 10158.85982806627 9886.18326006898 10907.375323662178 0.5883146832151344 0.6812413487387579 0.7427676234055962 0.8222308999188174 1.0698921464686315 1.0121372142376657 0.9677502295695078 0.9313752875110021 0.9063760040073205 1.0 13.413016362687443 -5.79433073493475 1.8060408627457192 0.9778776979205673 0.6398134768936269 0.8761442343688998 0.05280177268261479 0.1219196214072883 0.811469668279698 0.01791606474131328 0.035739437270060896 1.60571796026084e-06 5.79433073493475 -0.33806422102694045 SPESSESQTSQS(ph)ESR ddPTM_PC-9_Lapatinib_30min_R1 1 SPESSESQTSQSESR 15 0 A0A087WU78;A0A087WWC4;Q6T4R5-4;Q6T4R5-3;Q6T4R5-2;Q6T4R5 A0A087WU78 NHS Nance-Horan syndrome protein 1 SPESSESQTSQS(0.981)ES(0.019)R 181.97 7.2096e-29 0.0 1309.4 2077.1 1069.0 669.37 2436.2 698.45 1772.2 1042.1 2161.8 1136.8 True False 1290.727715885448 2072.290602566644 981.1109464593316 718.5977027528618 2292.907505753485 668.5789216664729 1863.9558445588032 1090.5197703730878 1918.3153192367922 1333.2943653092157 0.968074079864655 1.5542633768545489 0.7358547159477373 0.538964028837102 1.7197308902012178 0.5014488466029158 1.3980077416186465 0.817913732141346 1.4387785391952057 1.0 10.380779619093412 SPESSESQTSQSES(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPESSESQTSQSESR 15 0 A0A087WU78;A0A087WWC4;Q6T4R5-4;Q6T4R5-3;Q6T4R5-2;Q6T4R5 A0A087WU78 NHS Nance-Horan syndrome protein 1 SPESSESQTSQS(0.001)ES(0.999)R 155.63 0.00019651 1120500.0 3014.3 3451.8 2802.5 2037.5 3906.9 2364.7 2185.4 2659.4 2018.5 2038.1 True False 3524.561454861244 3794.471891848528 2869.3222285404363 1923.3454806641264 3141.3709909163176 2240.690969183564 1978.3830910741588 2589.5935678672145 2048.0167438731714 2407.591396409276 1.4639367212051997 1.5760447962672028 1.1917812270054602 0.7988670683624461 1.3047774616579098 0.9306774282901035 0.8217270978890994 1.0755951245420545 0.850649635535174 1.0 11.233374851014776 -5.448786517028773 3.804971577725086 0.9780113068947047 1.5140459863724942 0.7026574602259988 0.14208626356570403 0.12079963230695075 3.315562179534263 0.03769145231077485 0.08239199852225913 3.5580617663602193e-06 5.448786517028773 0.5360346794777895 SPFIYS(ph)PIIAHNR ddPTM_PC-9_Lapatinib_30min_R1 1 SPFIYSPIIAHNR 13 0 H0YBR0;Q96Q05-3;Q96Q05;Q96Q05-2 H0YBR0 TRAPPC9 Trafficking protein particle complex subunit 9 1 SPFIY(0.127)S(0.873)PIIAHNR 73.593 0.011858 2994300.0 25344.0 28667.0 21260.0 20767.0 25985.0 25585.0 22985.0 22719.0 21616.0 26323.0 True False 24982.58991247963 28600.623322795236 19512.084865973247 22294.274456681178 24456.613388475605 24490.789191548007 24175.050833531248 23774.607679787132 19181.378453428875 30872.895476807236 0.8092078675046012 0.9263991239267141 0.6320134397705387 0.7221309861729487 0.7921710293369872 0.7932780133935385 0.7830509727113987 0.7700802698485933 0.6213015707528494 1.0 14.91405317491379 -7.7799641018316175 21.287965094941967 0.7717682252040542 0.778490268527013 0.0 0.11073024794402543 1324.6493804281592 1522111.533908552 0.059014826033921136 0.02849660709799707 1.6597240922166414e-08 7.7799641018316175 0.006722043322958782 SPFNS(ph)PSPQDSPR ddPTM_PC-9_AZD4547_30min_R2 1 SPFNSPSPQDSPR 13 0 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 S(0.001)PFNS(0.701)PS(0.299)PQDSPR 146.27 0.0001028 7691900.0 17239.0 18359.0 19810.0 19203.0 20033.0 17879.0 19109.0 24562.0 17015.0 16552.0 True False 22720.64340652469 24293.18772018749 19547.30645637595 14776.045033392506 17251.763744750846 16761.023303634436 20809.66398096187 20766.507278610097 17914.37816318904 15972.519518036688 1.4224833709464435 1.5209364867424222 1.2238085816268685 0.9250916874264523 1.0800903217097086 1.0493662746636399 1.3028416686210913 1.3001397340701248 1.121574974002038 1.0 13.963304282121774 -5.390955227121761 4.438590781415227 1.124696943710827 1.4686826579007712 0.602026973204629 0.1149770278489288 0.1622868968743368 5.048074863067435 0.033432065960210616 0.07321316132446545 4.0648523293444316e-06 5.390955227121761 0.3439857141899443 SPFNSPS(ph)PQDSPR ddPTM_PC-9_AZD4547_30min_R2 1 SPFNSPSPQDSPR 13 0 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 S(0.001)PFNS(0.002)PS(0.998)PQDSPR 156.72 0.00021239 6627200.0 15198.0 17397.0 22740.0 16245.0 12547.0 18427.0 14689.0 14844.0 15572.0 16307.0 True False 20030.647861961963 23020.240033122816 22438.45274194795 12499.966232748075 10805.065626984917 17274.756777004975 15996.292543636451 12550.200881185907 16395.10412913192 15736.096893464497 1.2729108112114558 1.4628938922385235 1.4259223804898575 0.7943498516420263 0.6866420371033981 1.0977790041556947 1.016534954756158 0.7975421711084053 1.0418786971209564 1.0 13.941790125558294 -5.755090084167575 24.998630512789635 0.912611586128284 1.3948076515300067 0.7320380871648001 0.12968640660407035 76.66099239161909 301828.05724012066 0.036727116843600166 0.06168532811736411 1.7575590118994492e-06 5.755090084167575 0.4821960654017228 SPFNSPS(ph)PQDSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPFNSPSPQDSPR 13 0 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 SPFNS(0.108)PS(0.885)PQDS(0.006)PR 63.211999999999996 0.046356 16260000.0 14985.0 17307.0 16155.0 16897.0 16763.0 15080.0 17723.0 13819.0 9026.9 11135.0 True False 17521.66453275909 19025.12458202169 16540.196468178667 15950.315870813114 13478.410484202355 14289.178253177211 16044.149136591606 13456.265892440788 9158.901335283006 13153.687355388505 1.33207244929546 1.4463719615646715 1.257457017282903 1.2126117521167135 1.024686851681998 1.0863249115711682 1.219745361365838 1.023003324381762 0.6962991507876303 1.0 13.68317966451395 -5.952061356423245 0.4123371550293205 0.910327968872129 1.5268642352401638 0.6412733650646758 0.12001072053056017 1.4971490318771445 0.39384683564406 0.11656332497266644 0.4167804658417444 1.1167054702896008e-06 5.952061356423245 0.6165362663680348 SPFNSPS(ph)PQDSPR ddPTM_PC-9_Lapatinib_30min_R1 2 SPFNSPSPQDSPR 13 0 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 S(0.023)PFNS(0.041)PS(0.936)PQDS(0.001)PR;SPFNS(0.083)PS(0.68)PQDS(0.236)PR 72.428 0.023614 42805500.0 16298.2 29184.0 31377.0 31893.0 34150.0 28619.0 29237.0 24862.0 26416.0 22695.7 True False 16065.784679276174 29116.42624105961 28797.3041787226 34238.51761192916 32141.364141483242 27395.032084147424 30750.74880226031 26017.179283193254 23440.751907188052 26618.62150488068 0.6035543454543811 1.0938367426623103 1.081848065401976 1.2862618601662494 1.2074766582330319 1.0291679484275467 1.1552344585771273 0.9774052077949585 0.8806147945298389 1.0 14.700148240071712 -10.762557024802831 14.394916981919543 1.000000156271915 1.0522773877942782 0.0 0.18138291386183156 0.0 0.0 0.1789427798377247 0.04339999895368149 1.7275991241428646e-11 10.762557024802831 0.05227723152236319 SPFNSPSPQDS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 SPFNSPSPQDSPR 13 0 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 SPFNSPS(0.002)PQDS(0.998)PR 106.82 0.0010762 28700000.0 6878.1 9703.9 8884.0 9425.7 10442.0 10923.0 9248.1 9058.1 9592.4 7943.6 True False 9065.192726632493 12840.495904892827 8766.192355297522 7252.750490613326 8992.308542040055 10239.983083259642 10071.162984056384 7658.378779430751 10099.434680727274 7665.496981843666 1.182596868553222 1.6751028583412861 1.14359086906706 0.9461552861858844 1.1730887851549674 1.3358537753669266 1.3138304023745269 0.9990713971410106 1.3175185776797749 1.0 12.904163614706366 -5.306006853818987 24.86521753768794 1.1591187509647645 1.4288501233363513 0.2885072295698654 0.17270385864107426 452.2742488323078 252333.36647773575 0.04433769679501198 0.09229703680467577 4.943028860835772e-06 5.306006853818987 0.26973137237158684 SPFNSPSPQDS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPFNSPSPQDSPR 13 0 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 SPFNS(0.022)PS(0.405)PQDS(0.572)PR;S(0.003)PFNS(0.004)PS(0.016)PQDS(0.976)PR 160.63 0.00029129 23032000.0 46247.0 65624.0 52775.0 40858.0 47982.0 37726.0 37161.0 31271.0 38829.0 32052.0 True False 54075.70368011405 72138.71702609312 54033.35615030202 38568.858723423225 38580.27154166903 35747.58214717264 33640.84105765846 30450.169384363264 39396.800667749005 37862.77387650762 1.4282023777889639 1.9052676188326598 1.4270839301562006 1.018648523988722 1.0189499498241092 0.9441353204539676 0.8884938321576933 0.8042244734545562 1.040515435985877 1.0 15.208492488195064 -5.6770591457338995 2.8327924186490536 0.9417608111642789 1.6720080393224557 0.8430708275241168 0.12675222215568707 0.08563074704108434 1.3819560301939102 0.03471393403374611 0.06585457895620202 2.1034919497178056e-06 5.6770591457338995 0.7302472281581768 SPFNSPSPQDS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 SPFNSPSPQDSPR 13 0 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 SPFNS(0.017)PS(0.183)PQDS(0.8)PR;SPFNSPSPQDS(1)PR 188.19 2.9905999999999998e-05 17169700.0 11006.3 22732.8 18259.8 14133.400000000001 22278.0 21188.8 26605.0 26776.0 24535.7 20155.5 True False 10849.34814369177 22680.163598299067 16758.549728866343 15172.817383640277 20967.65184023319 20282.60441750527 27982.47672073523 28020.110710593814 21772.231093624843 23639.351319484413 0.4589528704516246 0.9594241098995492 0.7089259558088354 0.6418457587342631 0.8869808463378134 0.8580017337780166 1.1837243900035048 1.185316396034041 0.9210164356616409 1.0 14.528902827036003 -6.844679532271227 1.8029251001693392 1.0829006053017558 0.7194977726117457 0.5536737234381159 0.1450899393625485 0.2607963501661363 1.7449419088998288 0.06090975384177393 0.0523345614566136 1.4299487344999222e-07 6.844679532271227 -0.36340283269001006 SPFS(ph)VAVSPSLDLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPFSVAVSPSLDLSK 15 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 S(0.006)PFS(0.426)VAVS(0.378)PS(0.185)LDLS(0.006)K 75.416 0.014994 5369100.0 21078.0 19932.0 19110.0 24652.0 27130.0 25201.0 30991.0 29392.0 27225.0 24464.0 True False 24646.089090523597 21910.717234001062 19565.65487507859 23270.828362862358 21814.071254334543 23879.415196175 28055.308124590116 28620.49114339822 27623.11412036023 28899.12954308256 0.8528315378420458 0.7581791417397802 0.6770326713789179 0.8052432281107436 0.7548348894666299 0.8263022303345083 0.9708011475835463 0.9903582424768557 0.9558458873018976 1.0 14.818738418199603 -7.162481394532943 2.6996059246072868 0.9821653191770797 0.7661228409646049 0.8423888700021367 0.042967854468736154 0.10796426357926672 1.53066207446435 0.019180477285486896 0.013873403586352065 6.878893813203012e-08 7.162481394532943 -0.2160424782124748 SPFSVAVSPS(ph)LDLSK ddPTM_PC-9_AZD4547_30min_R2 1 SPFSVAVSPSLDLSK 15 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 S(0.103)PFS(0.031)VAVS(0.348)PS(0.516)LDLS(0.002)K 111.92 0.00037181 8295700.0 18915.0 13467.0 24618.0 30558.0 24368.0 19545.0 18348.0 18980.0 18450.0 18564.0 True False 24929.57654355907 17819.944388461514 24291.54923488455 23513.325216393696 20984.923822297646 18322.848060268196 19980.936455214207 16047.07711701081 19425.22933357848 17914.08001044183 1.3916191358433154 0.9947451601240228 1.3560031673814896 1.3125611364182896 1.171420681947712 1.022818255226509 1.1153760864955184 0.8957801409649407 1.0843553965515296 1.0 14.128806334431957 -6.641939973422378 3.1761056113340373 1.0210339417386103 1.251069165844092 0.49719272996458175 0.1139417289692981 0.22210058969952418 4.458549850765801 0.03918143961883208 0.03892070620286719 2.280657274233307e-07 6.641939973422378 0.23003522410548172 SPFSVAVSPS(ph)LDLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPFSVAVSPSLDLSK 15 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 SPFSVAVS(0.047)PS(0.953)LDLSK 132.51 6.499e-06 5798700.0 16260.0 18758.0 19405.0 24286.0 24682.0 20543.0 23396.0 26304.0 19803.0 19417.0 True False 19012.496850361214 20620.17027269677 19867.688793872316 22925.334156274326 19845.73928121951 19465.688916115338 21179.761507628373 25613.547871391762 20092.581411404728 22937.14839511256 0.8288954024647803 0.8989857813838145 0.8661795464559892 0.9994849299208985 0.8652226048050609 0.8486533975715604 0.9233825034737688 1.116684054625094 0.8759842795317159 1.0 14.485398422518255 -7.536972421011811 24.970840525470585 1.0018071898359764 0.8885072299035478 0.34762671654555044 0.06902159939827122 252.68547045561814 447696.46798604244 0.030906281394579932 0.017853337330163744 2.904207074375033e-08 7.536972421011811 -0.11329995993242858 SPFSVAVSPS(ph)LDLSK ddPTM_PC-9_Lapatinib_30min_R1 3 SPFSVAVSPSLDLSK 15 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 SPFS(0.001)VAVS(0.283)PS(0.716)LDLSK;SPFS(0.001)VAVS(0.206)PS(0.787)LDLS(0.007)K;S(0.04)PFS(0.243)VAVS(0.16)PS(0.556)LDLSK 144.5 0.00010628 19253200.0 61746.0 46497.1 53001.7 47305.7 53310.4 45198.2 41659.1 45217.9 51717.5 41848.3 True False 60865.49071717039 46389.4388217233 48644.104818478576 50784.7189851891 50174.78708427901 43265.178348150264 43816.00435845819 47318.88871005975 45892.53054058137 49081.722895645325 1.2400846410094246 0.9451469118220197 0.991083889249422 1.0346971538298397 1.0222702897157399 0.8814926574631079 0.8927152873507965 0.9640836938561914 0.9350228116106554 1.0 15.582898271773113 -4.759323075496157 24.99724714108577 0.9620587694754805 1.2400849971742443 0.7462361016181438 0.04848116834905503 30.785376257232915 363540.63781599025 0.013371646415923427 0.08564995184641185 1.740511609732152e-05 4.759323075496157 0.27802622769876373 SPFSVAVSPSLDLSK ddPTM_PC-9_Lapatinib_30min_R1 2 SPFSVAVSPSLDLSK 15 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 172.76 0.00041882 11505300.0 84345.0 85600.0 85308.0 86104.0 85386.0 80946.0 82645.0 81774.0 78490.0 86556.0 False True 83142.22483302152 85401.79845924833 78294.30553840302 92436.37539452389 80363.76335533487 77484.12827434215 86923.95371490935 85573.51857066412 69649.62966365798 101517.08927137978 0.8189973277382118 0.8412553893359631 0.771242616394402 0.9105498991152027 0.7916279311407665 0.7632619180718263 0.8562494683288304 0.8429469282940665 0.6860877332432931 1.0 16.631363083933877 -10.870472220973957 5.286328140855292 1.0000667188580992 0.8124644642843704 0.4911539275660105 0.058192805351533934 4.4192414092713494e-05 5.453849257324089e-06 0.054416245567448826 0.013193193259365507 1.347496913302774e-11 10.870472220973957 -0.1876022545737288 SPFTVGVAAPLDLSK ddPTM_PC-9_Lapatinib_30min_R1 2 SPFTVGVAAPLDLSK 15 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 142.12 6.0478e-05 10861000.0 44627.0 47797.0 51512.0 51254.0 55502.0 49742.0 52132.0 41368.0 47345.0 45543.0 False True 43990.6107964105 47686.328983138905 47276.882202070294 55023.3901383318 52237.481481130366 47614.65061426541 54831.139876164954 43290.1083013088 42012.50753504765 53415.046867767036 0.8235621491695508 0.8927508591575328 0.8850854763660092 1.0301103034608645 0.9779544256592749 0.891408945725332 1.0265111254494181 0.8104478202270742 0.7865294518799687 1.0 15.704958581830711 -10.566722691487719 17.11177663890114 0.9999999233626675 0.9084514904081319 0.11029207495453663 0.08144227040972139 0.0 0.0 0.08290363104577556 0.020107083973468717 2.711922713534882e-11 10.566722691487719 -0.09154843295453563 SPGAGSLGS(ph)PASQR ddPTM_PC-9_AZD4547_30min_R2 4 SPGAGSLGSPASQR 14 0 E9PC47;P53667-4;P53667-2;P53667 E9PC47 LIMK1 LIM domain kinase 1 1 SPGAGSLGS(0.997)PAS(0.003)QR;SPGAGS(0.001)LGS(0.997)PAS(0.001)QR;SPGAGS(0.011)LGS(0.964)PAS(0.024)QR;SPGAGS(0.001)LGS(0.993)PAS(0.005)QR 175.27 0.00011840000000000002 92631000.0 51717.3 75606.4 115724.0 120699.0 120743.0 127697.0 131383.0 162370.0 122007.0 111793.0 True False 68162.3256133338 100044.69023626464 114189.42414728177 92873.71033096078 103979.91862589003 119712.08640327782 143075.83247740404 137279.44739141452 128456.04093777292 107879.16109714101 0.6318395964532599 0.927377347198485 1.0584938090541751 0.8609050106288053 0.9638554616888441 1.1096868494878425 1.3262601509161698 1.2725298008926829 1.190740080209775 1.0 16.71905668230854 -6.79666017027286 2.486299349225332 1.2203166517140664 0.8891347010433118 0.5734280518753804 0.12771012297091844 0.20642303179125196 2.613559490266515 0.049398194898223204 0.04473570843311601 1.5971283904002092e-07 6.79666017027286 -0.3311819506707546 SPGAGSLGS(ph)PASQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGAGSLGSPASQR 14 0 E9PC47;P53667-4;P53667-2;P53667 E9PC47 LIMK1 LIM domain kinase 1 1 SPGAGS(0.009)LGS(0.892)PAS(0.099)QR 128.73 2.478e-05 10925000.0 6904.0 11120.0 14582.0 13597.0 12579.0 12899.0 9078.4 10453.0 8446.4 9012.7 True False 8072.7108397843685 12223.920110480223 14929.690182542952 12835.204172068765 10114.235249107049 12222.553732608274 8218.4282300758 10178.619825868996 8569.912620981106 10646.631165506058 0.7582408664572776 1.148149111249802 1.4022924200580504 1.2055648376036026 0.9499939550715427 1.1480207722615616 0.7719275799374572 0.9560413681697392 0.8049412520973491 1.0 13.378109380923048 -7.249611786659993 24.240479569902384 0.879564329835135 1.1155812044886606 0.2852609864788892 0.16882902926390708 642.8352144392408 1317483.221837833 0.06753292182405947 0.05184869906728226 5.62844223602763e-08 7.249611786659993 0.2360168746535256 SPGAGSLGS(ph)PASQR ddPTM_PC-9_Lapatinib_30min_R1 4 SPGAGSLGSPASQR 14 0 E9PC47;P53667-4;P53667-2;P53667 E9PC47 LIMK1 LIM domain kinase 1 1 SPGAGSLGS(1)PASQR;SPGAGSLGS(0.978)PAS(0.022)QR;SPGAGSLGS(0.983)PAS(0.017)QR;SPGAGSLGS(0.999)PAS(0.001)QR 238.65 4.2111000000000006e-27 97628000.0 96330.0 143235.0 139737.0 143449.0 134513.0 110625.0 108606.0 127045.0 118478.0 91936.0 True False 94956.31653524152 142903.34815783252 128248.36326041911 153998.71799183576 126601.20980273314 105893.82662947032 114229.08726676085 132947.9745005746 105133.76001135005 107827.01510298021 0.8806356778452364 1.3253019015814604 1.189389905098787 1.4282016231717 1.1741140166202564 0.9820713902572227 1.0593735452814523 1.2329746341731025 0.9750224460070794 1.0 16.718359152270516 -6.554802697300081 10.651790293735601 1.0663614788708946 1.2241915424792091 0.19824851829101175 0.14790076008780748 0.8103035794736418 264.63122725601744 0.04795143839086255 0.04804796249358707 2.787387208468785e-07 6.554802697300081 0.15783006360831453 SPGAPSAGEAEARPSPS(ph)TTPLPDSSPSR ddPTM_PC-9_Lapatinib_30min_R1 1 SPGAPSAGEAEARPSPSTTPLPDSSPSR 28 1 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 SPGAPSAGEAEARPS(0.09)PS(0.211)T(0.211)T(0.211)PLPDS(0.106)S(0.135)PS(0.035)R 42.73 0.025018000000000002 7773800.0 5401.9 8267.6 8707.8 4825.3 7247.4 8679.4 4421.9 6982.7 7547.3 5613.6 True False 5324.867915412861 8248.456880159834 7991.87829708005 5180.168658728928 6821.122180936622 8308.202294669596 4650.844345477133 7307.141733599614 6697.243597407649 6583.903280348176 0.8087706773133622 1.2528216969377521 1.2138511087996142 0.7867929460918486 1.0360301314414055 1.2618961641596647 0.7063962132249281 1.109849495421687 1.0172147603379555 1.0 12.684727426924214 -7.234499790908005 24.941394258352407 0.9675190292433572 1.0622719556805342 0.06857503046326274 0.1821931137353716 2399.9103290805806 2221904.42569748 0.06979538445495183 0.05404965612670343 5.827740553740996e-08 7.234499790908005 0.09475292643717703 SPGAPSAGEAEARPSPSTTPLPDS(ph)SPSR ddPTM_PC-9_AZD4547_30min_R2 1 SPGAPSAGEAEARPSPSTTPLPDSSPSR 28 1 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 SPGAPSAGEAEARPS(0.006)PS(0.006)T(0.006)T(0.006)PLPDS(0.416)S(0.416)PS(0.145)R 52.666000000000004 0.0039639 11065000.0 6941.6 5357.6 8206.6 9414.1 6729.7 5986.4 5954.8 9989.3 7814.9 7303.1 True False 9148.884405750436 7089.339426421733 8097.775121902814 7243.824691395116 5795.397318077664 5612.069461652061 6484.765664023848 8445.683216277981 8227.979659565448 7047.420691890639 1.2981890546534165 1.0059480959579055 1.1490409719999832 1.0278689194375008 0.8223430346291574 0.7963295660935618 0.9201615665552321 1.1984076991453485 1.1675164601757435 1.0 12.782879622188558 -1.7376794467835155 1.0166522135101654 0.9925252262127681 199.9999978824613 0.2982987260593002 0.13082307327847068 1675.3487878090507 3.453579791103724 0.047760257077137346 775159.7325741329 0.01829450036936818 1.7376794467835155 199.00747265624852 SPGAPSAGEAEARPSPSTTPLPDS(ph)SPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPGAPSAGEAEARPSPSTTPLPDSSPSR 28 1 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 SPGAPSAGEAEARPS(0.002)PS(0.048)T(0.048)T(0.048)PLPDS(0.377)S(0.377)PS(0.1)R;SPGAPSAGEAEARPSPS(0.002)T(0.002)T(0.004)PLPDS(0.448)S(0.439)PS(0.106)R;SPGAPSAGEAEARPS(0.011)PS(0.026)T(0.026)T(0.02)PLPDS(0.377)S(0.377)PS(0.164)R 62.193000000000005 0.00045575 16245700.0 49807.4 50985.6 56187.8 58893.4 65664.5 67241.4 60021.5 71369.3 55956.2 49236.5 True False 58238.80907900865 56047.11341590833 57527.53024541816 55593.79373297899 52798.01260155742 63715.14261228056 54335.82900197107 69495.931497024 56774.45356626999 58162.68769408046 1.0013087666328035 0.963626607331156 0.989079640679553 0.9558326125743513 0.907764319270462 1.0954642080401178 0.9342042322349751 1.1948541969475903 0.9761318779642338 1.0 15.827806317192959 -6.76443498016739 24.999999887931185 1.045688869224221 0.9645208183687175 0.22729673865407718 0.07023990596973642 111.68168150584647 932037.8486501802 0.022937728754928183 0.021097955035183948 1.7201448512069683e-07 6.76443498016739 -0.08116805085550349 SPGAPSAGEAEARPSPSTTPLPDSS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 1 SPGAPSAGEAEARPSPSTTPLPDSSPSR 28 1 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 SPGAPSAGEAEARPS(0.035)PS(0.035)T(0.035)T(0.035)PLPDS(0.304)S(0.441)PS(0.115)R 52.486000000000004 0.0042349 12930000.0 8280.1 7298.1 7802.6 12739.0 9300.9 11277.0 6344.7 12552.0 8754.8 12059.0 True False 10912.999563220896 9657.068102875994 7699.132425871725 9802.220365588033 8009.630580220298 10571.847407298259 6909.366008687463 10612.376816265529 9217.560854721567 11636.818080473937 0.9377992753476505 0.8298718804481549 0.6616183541436063 0.8423454158861281 0.6883007472343408 0.9084826568731318 0.5937504531656357 0.9119655169373684 0.7921032013199746 1.0 13.506409007634833 -9.0784348788986 1.1126140990323938 0.9998301963518604 0.7867958397527859 0.23482136435769707 0.10975968215450829 3.283718493876321 5.293620435163021 0.10114974349246585 0.030929544200597077 8.347667095547096e-10 9.0784348788986 -0.21303435659907455 SPGAPSAGEAEARPSPSTTPLPDSS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 1 SPGAPSAGEAEARPSPSTTPLPDSSPSR 28 1 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 SPGAPSAGEAEARPS(0.009)PS(0.009)T(0.007)T(0.007)PLPDS(0.393)S(0.47)PS(0.104)R 67.675 0.00010889999999999999 10646000.0 5329.8 7091.0 7676.5 8838.2 6220.7 8952.0 5985.1 6219.6 7768.3 7225.5 True False 5253.796074634385 7074.581225169744 7045.367802146927 9488.190711370908 5854.810656366756 8569.143828131233 6294.979192680789 6508.585321766104 6893.352250174477 8474.418047626436 0.6199595116865753 0.8348161709052381 0.83136892262711 1.1196274078110195 0.6908805564538565 1.011177850794289 0.7428214134944551 0.7680274073320075 0.8134307525819083 1.0 13.048898584046126 -4.726323971950012 2.9665537652851275 0.8655293863999841 0.5580619989023803 0.2566342287423361 0.1276140147569194 0.7230088804480704 7.970388543597666 0.03161533122798792 0.5713193550655511 1.8779154199991657e-05 4.726323971950012 -0.30746738749760383 SPGDPAKPASS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 SPGDPAKPASSPR 13 1 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3;H7C3V8 C9JWC4 HJURP Holliday junction recognition protein 1 SPGDPAKPAS(0.227)S(0.773)PR 90.476 0.039687 0.0 7367.8 7679.3 9769.4 8599.1 11463.0 7600.8 7643.0 9308.5 10300.0 7855.2 True False 7262.73382091096 7661.519052664785 8966.197642974557 9231.50649975669 10788.768877125101 7275.731502330198 8038.7171425137885 9741.00689234995 9139.905536191589 9212.960853603929 0.7883170173321558 0.8316022584278918 0.973215645377149 1.002012995219176 1.171042518096096 0.7897278212665014 0.8725443720266326 1.057315563056958 0.9920703757919733 1.0 13.16944916761655 -5.208695555399126 3.3903490532814695 0.9819658000085573 0.7968788543193894 0.34606632221036193 0.09557530653373578 0.29208087476400635 6.722288499798621 0.02666217416638863 0.08159080969143853 6.184497874542186e-06 5.208695555399126 -0.18508694568916784 SPGEDAS(ph)PGAGHEQEAFLGVR ddPTM_PC-9_AZD4547_30min_R2 1 SPGEDASPGAGHEQEAFLGVR 21 0 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 S(0.374)PGEDAS(0.626)PGAGHEQEAFLGVR 55.871 0.009415399999999999 15906000.0 11753.0 7618.0 16254.0 15410.0 16479.0 17021.0 12677.0 14799.0 14892.0 12187.0 True False 15490.2095224134 10080.369521890534 16038.461339825057 11857.462582126673 14191.175298245354 15956.674179269643 13805.228441396906 12512.154597188766 15679.16071737944 11760.336839434094 1.3171569602047883 0.8571497278963652 1.3637756774147658 1.0082587551716122 1.2066980301669856 1.3568211860875132 1.1738803598810195 1.0639282503570577 1.3332237784894876 1.0 13.52164176197047 -4.472817926219356 23.932800195056338 1.1599669391701455 3.7975953779478826 0.08401085810307563 0.16192942745115985 1562.3647112417382 845215.5055722994 0.0367492470216357 28102.051818075604 3.366526781885889e-05 4.472817926219356 2.637628438777737 SPGEDAS(ph)PGAGHEQEAFLGVR ddPTM_PC-9_Lapatinib_30min_R1 4 SPGEDASPGAGHEQEAFLGVR 21 0 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 S(0.218)PGEDAS(0.782)PGAGHEQEAFLGVR;S(0.005)PGEDAS(0.995)PGAGHEQEAFLGVR;S(0.003)PGEDAS(0.997)PGAGHEQEAFLGVR;S(0.167)PGEDAS(0.833)PGAGHEQEAFLGVR 102.79 7.3311e-05 53158400.0 92701.7 82905.6 95048.5 82153.8 87990.0 85112.9 74593.3 73029.2 100169.3 71796.3 True False 91379.7567585902 82713.63717690497 87233.97922782009 88195.66450904297 82814.60119499596 81472.81967486057 78455.37608618005 76422.40323820207 88887.17860450839 84206.19479244367 1.0851904302744988 0.9822749665957755 1.0359567896737227 1.0473773898278242 0.9834739759838598 0.9675395008132064 0.9317055150106407 0.9075627206118558 1.0555895421186372 1.0 16.361638751411057 -6.415532108993804 3.7570558874204245 0.9648574780888847 1.0334510038476172 0.3246338195938986 0.044052028521548076 0.27810280035837726 7.057008836346918 0.014059187872283045 0.015888384036295163 3.8412085865622196e-07 6.415532108993804 0.06859352575873257 SPGGGGGGGSGNDNNQAAT(ph)KSPR ddPTM_PC-9_AZD4547_30min_R2 1 SPGGGGGGGSGNDNNQAATKSPR 23 1 Q9NS37;E9PIM0;J3KN20 Q9NS37 CREBZF CREB/ATF bZIP transcription factor 1 SPGGGGGGGSGNDNNQAAT(0.5)KS(0.5)PR 113.33 1.0407999999999999e-07 1664700.0 2205.2 1136.0 3037.4 4302.5 3979.5 2184.7 2298.4 2893.7 2784.2 2716.9 True False 2906.4077289905604 1503.189784309221 2997.1220913980974 3310.625097962363 3427.0151161701206 2048.090363636118 2502.953147409217 2446.5451556108633 2931.3671279430455 2621.7821579600004 1.1085618689433856 0.5733465611341438 1.143162135838985 1.262738434583882 1.307131908639072 0.7811825087823964 0.954676245625516 0.9331611126358841 1.1180818814572802 1.0 11.356332102682822 -5.304286591381289 24.99949998323917 1.06211761570767 0.8409531431851238 0.17741394330668225 0.19083116331281544 725.9953540133909 423585.6160684559 0.05172732466123054 0.1076800106017595 4.96264727761391e-06 5.304286591381289 -0.22116447252254612 SPGGGGGGGSGNDNNQAAT(ph)KSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGGGGGGGSGNDNNQAATKSPR 23 1 Q9NS37;E9PIM0;J3KN20 Q9NS37 CREBZF CREB/ATF bZIP transcription factor 1 SPGGGGGGGSGNDNNQAAT(0.5)KS(0.5)PR 52.095 0.015667 1195800.0 1103.2 944.0 569.89 2705.3 2928.1 2198.9 1067.3 2201.0 2059.7 980.05 True False 1289.9499708067945 1037.7140813213418 583.4783389198608 2553.7308117009366 2354.3598245417243 2083.585813057782 966.1976174171544 2143.2260821522686 2089.81921593043 1157.7253069284684 1.1142107398767398 0.8963387732056015 0.5039868571827909 2.2058175600187706 2.0336083269942646 1.7997238210035251 0.834565515355753 1.8512388641122541 1.8051080022383514 1.0 10.177077270853546 -5.75311079138879 24.99992286877568 1.6712218012951676 0.8439947652614773 0.4287085176212253 0.427300482220718 178.66398309727222 536289.896999534 0.12009431753556031 0.2036701517303653 1.765587350243235e-06 5.75311079138879 -0.8272270360336903 SPGGGGGGGSGNDNNQAAT(ph)KSPR ddPTM_PC-9_Lapatinib_30min_R1 2 SPGGGGGGGSGNDNNQAATKSPR 23 1 Q9NS37;E9PIM0;J3KN20 Q9NS37 CREBZF CREB/ATF bZIP transcription factor 1 SPGGGGGGGSGNDNNQAAT(0.84)KS(0.16)PR;SPGGGGGGGSGNDNNQAAT(0.794)KS(0.206)PR 83.436 4.1811e-05 1435400.0 5187.9 6006.4 4489.58 5213.34 4727.0 5827.700000000001 8085.5 2910.5 7566.799999999999 5449.9 True False 5113.91959465566 5992.492549832117 4120.464062679971 5596.746414792419 4448.96715363957 5578.462856032221 8504.127627344653 3045.7324553026306 6714.547302063541 6391.907953464717 0.8000615202669922 0.9375123348864719 0.6446375781188283 0.8755987188080074 0.6960311672241805 0.8727382960839462 1.3304521418733841 0.4764981719819196 1.05047621945556 1.0 12.642030917578143 -6.99897093701655 24.999519417658636 0.9465691466308837 0.7944020844996683 0.12952881528139792 0.21004669058513742 83.04862563853011 2017477.1023383907 0.07232878295811127 0.0632699578683453 1.0023723145812198e-07 6.99897093701655 -0.15216706213121534 SPGGGGGGGSGNDNNQAATKS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 SPGGGGGGGSGNDNNQAATKSPR 23 1 Q9NS37;E9PIM0;J3KN20 Q9NS37 CREBZF CREB/ATF bZIP transcription factor 1 SPGGGGGGGSGNDNNQAAT(0.272)KS(0.728)PR 73.346 0.00025968 1681100.0 2362.7 1620.1 5113.9 7612.4 5529.1 6013.2 4893.4 3839.0 2453.3 5622.5 True False 3113.989452787047 2143.7656422177547 5046.086344637097 5857.478790407598 4761.479904213145 5637.193653415438 5328.903120228102 3245.770761443861 2582.9764294887837 5425.657986355811 0.5739376607626137 0.3951162508969042 0.9300413622323332 1.079588651761263 0.8775857077956426 1.0389880209168338 0.9821671645409601 0.5982262003255959 0.47606694634721375 1.0 12.405582392926945 -5.264606859529835 24.76313353042984 0.8758767188942618 0.4845269394582013 0.4074975491161309 0.18726213580889725 233.66075070257705 1826761.8505962759 0.05320349963619546 0.11879199621964259 5.437423257416755e-06 5.264606859529835 -0.3913497794360605 SPGGGGGGGSGNDNNQAATKS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGGGGGGGSGNDNNQAATKSPR 23 1 Q9NS37;E9PIM0;J3KN20 Q9NS37 CREBZF CREB/ATF bZIP transcription factor 1 SPGGGGGGGS(0.001)GNDNNQAAT(0.247)KS(0.752)PR 47.75 0.021339 1212700.0 951.22 878.38 437.12 2073.1 1179.1 2311.2 2440.8 2781.9 1056.0 949.66 True False 1112.2427585486214 965.5797613888143 447.54259858683173 1956.9509280808838 948.0638192401717 2189.9966033649307 2209.589754138285 2708.878072666694 1071.442002244276 1121.8258404955766 0.9914576027748463 0.8607216258829096 0.3989412459862092 1.7444338126641683 0.8451078456361426 1.9521716511695613 1.9696370634163491 2.414704649226143 0.9550876469122488 1.0 10.13163300467663 -6.241812283138221 1.3053150102808344 1.7303681512510038 0.807148820831428 0.26064940706158135 0.5320023859130024 0.5092430930496894 1.7612280951337593 0.20437362840177686 0.29643798954099754 5.730436664471559e-07 6.241812283138221 -0.9232193304195758 SPGHILCCECGVPIS(ph)PNPANICVACLR ddPTM_PC-9_AZD4547_30min_R2 1 SPGHILCCECGVPISPNPANICVACLR 27 0 C9JA08;Q96D46;C9IY70;C9IZW9;C9K0C2;C9J0B9 C9JA08 NMD3 60S ribosomal export protein NMD3 1 SPGHILCCECGVPIS(1)PNPANICVACLR 96.708 1.5128e-09 4977900.0 757.17 1025.9 5511.5 16947.0 11511.0 8704.3 3694.5 11509.0 4705.5 10605.0 True False 997.9343098856253 1357.5021124320697 5438.413908849874 13040.130978539957 9912.896344323219 8160.018744998334 4023.30334280515 9730.548500509869 4954.223123531354 10233.722177910775 0.09751430540489371 0.1326498891441672 0.5314209057373621 1.2742314821372367 0.9686501325705275 0.7973656703922961 0.3931417399125165 0.95083180208986 0.48410764308463605 1.0 13.321043352679682 -5.417052343952605 3.758066780570567 0.8260306503791717 0.11962957252779086 0.5832444905042664 0.2419521338516472 0.16879606133193775 4.2386548720011055 0.06770685099674748 0.15155424911515972 3.827786056072365e-06 5.417052343952605 -0.7064010778513808 SPGKAEAES(ph)DALPDDTVIESEALPSDIAAEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGKAEAESDALPDDTVIESEALPSDIAAEAR 32 1 G3V529;Q9GZR7-2;Q9GZR7;A0A1W2PRR2;F5GYL3 G3V529 DDX24 ATP-dependent RNA helicase DDX24 1 S(0.264)PGKAEAES(0.735)DALPDDT(0.001)VIESEALPSDIAAEAR 77.791 2.6636e-05 0.0 3629.4 3918.5 3675.3 5085.5 5568.5 5201.6 5906.5 5285.6 4757.9 4343.9 True False 4243.785736082469 4307.502783535679 3762.9330906528676 4800.575922413454 4477.392398811722 4928.818939106534 5346.993560643142 5146.858600556121 4827.475286437532 5131.414683706523 0.8270206166649346 0.8394376695403389 0.7333129989671437 0.9355267929634372 0.8725454235902083 0.9605185398008704 1.0420115874908988 1.0030096801372606 0.9407688881130439 1.0 12.325140903049082 -6.421823544960546 1.2019639399669895 0.997245530465656 0.8098446146706921 0.7115902911239089 0.04878505047551059 0.24793631009385525 0.7446116807421667 0.021280118108585273 0.026544554231980825 3.7859637821874e-07 6.421823544960546 -0.18740091579496387 SPGLVPPS(ph)PEFAPR ddPTM_PC-9_AZD4547_30min_R2 2 SPGLVPPSPEFAPR 14 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 S(0.03)PGLVPPS(0.97)PEFAPR;S(0.001)PGLVPPS(0.999)PEFAPR 94.45 0.0034427 24619000.0 106138.0 112844.0 134012.0 122384.0 130042.0 139444.0 119558.0 160119.0 123709.0 134145.0 True False 139887.67619245395 149318.61621530788 132234.91331811468 94170.2596139513 111987.91298831387 130724.54463627716 130198.43038546456 135376.28771857993 130248.00518307094 129448.62438056033 1.0806424314035528 1.1534971262138145 1.0215242838685026 0.7274720767762219 0.8651147397216483 1.0098565763971799 1.0057923057003673 1.045791628658742 1.0061752746028458 1.0 16.98202010858261 -5.51965149835467 24.99990174840873 0.9483138297919063 1.109680043930778 0.3491120047791929 0.09003827031634594 149.34082586853265 1156869.3563652888 0.02723719605287703 0.048406640224407466 3.022376067418184e-06 5.51965149835467 0.16136621413887164 SPGLVPPS(ph)PEFAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPGLVPPSPEFAPR 14 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 S(0.195)PGLVPPS(0.805)PEFAPR;S(0.001)PGLVPPS(0.999)PEFAPR;S(0.14)PGLVPPS(0.86)PEFAPR 98.676 0.0023945 16403000.0 120455.0 127716.0 124643.0 106131.0 127750.0 89674.0 107465.0 76765.0 94411.0 82832.0 True False 140845.652405305 140394.80043436086 127614.96183121006 100184.82415134445 102718.30456104824 84971.33757794519 97285.13722077633 74750.0000892407 95791.58226693585 97848.78590224862 1.439421563656502 1.4348139237477704 1.304205879045837 1.0238739625387845 1.0497657545149746 0.8683943985041566 0.9942395945307346 0.7639338536496129 0.9789756856322374 1.0 16.578266329699723 -5.726559969717605 1.273036567464628 0.9167835833407424 1.474525393316511 0.8816746997146475 0.07518344436604597 0.1425051168525322 0.4526962414345043 0.024713556470687556 0.06613450620200331 1.87689522869356e-06 5.726559969717605 0.5577418099757686 SPGLVPPS(ph)PEFAPR ddPTM_PC-9_Lapatinib_30min_R1 3 SPGLVPPSPEFAPR 14 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 SPGLVPPS(1)PEFAPR;S(0.001)PGLVPPS(0.999)PEFAPR;S(0.001)PGLVPPS(0.999)PEFAPR 116.0 0.00015092 22411000.0 75046.0 108567.0 109200.0 93739.0 116234.0 98301.0 91097.0 98208.0 105500.0 90768.0 True False 73975.83027824921 108315.6197818367 100221.99752418988 100632.87876413703 109397.34464483653 94096.89538082306 95813.55691895579 102771.10220593042 93617.47903574866 106457.12785924246 0.6948884660504837 1.0174576560533508 0.9414305978337433 0.9452901913453249 1.0276187874379028 0.8838947402867933 0.9000201193257853 0.9653754922057854 0.87939136550377 1.0 16.69991302340891 -4.751707788856105 24.999777935879578 0.9482833364588809 0.694887959158301 0.6998126838691507 0.050322191083054135 222.75460347332933 572201.4396743015 0.012328378038185133 0.15882141324131221 1.7713003610087775e-05 4.751707788856105 -0.2533953773005798 SPGQMT(ph)VPLCIGVSTDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGQMTVPLCIGVSTDK 17 0 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3 C9JWC4 HJURP Holliday junction recognition protein 1 S(0.18)PGQMT(0.82)VPLCIGVSTDK 101.38 0.0040766 6207500.0 22257.0 25953.0 26443.0 27463.0 29615.0 22777.0 26558.0 24479.0 19795.0 20425.0 True False 26024.67050421213 28529.442322598312 27073.501405635954 25924.33714624732 23812.15334305632 21582.534023383112 24042.233976730815 23836.452187644405 20084.464426539234 24127.890815788967 1.0786135722722159 1.1824258713873583 1.1220832194714434 1.074455174891739 0.9869140044132647 0.8945056237265377 0.9964498828466971 0.9879210897309827 0.8324169145110782 1.0 14.558414184759206 -6.188271640375624 2.0989604861078015 0.9441682707364095 1.13293171859443 0.7043969026066929 0.05355403790225776 0.1730339814543315 1.4971038941796566 0.01753938734127234 0.02392147915442091 6.482288557269374e-07 6.188271640375624 0.18876344785802057 SPGS(ph)NSKVPEIEVTVEGPNNNNPQTSAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPGSNSKVPEIEVTVEGPNNNNPQTSAVR 29 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347 A0A494C1K3 GTF2I General transcription factor II-I 1 S(0.148)PGS(0.542)NS(0.303)KVPEIEVT(0.007)VEGPNNNNPQTSAVR;S(0.181)PGS(0.635)NS(0.181)KVPEIEVT(0.002)VEGPNNNNPQTSAVR 80.832 9.493799999999998e-07 34407400.0 14972.5 4329.8 7701.4 26431.0 25228.0 57714.0 24813.8 45167.0 38999.0 28084.0 True False 17507.048529645348 4759.633929348673 7885.030583722141 24950.156760458165 20284.754500713316 54687.37624030961 22463.257227645277 43981.4141083923 39569.28659614063 33175.40688717833 0.5277116446282831 0.14346874314262537 0.23767698194440404 0.752067844873997 0.6114395090826449 1.6484312137086479 0.6771057037533096 1.3257234269337714 1.1927295038371755 1.0 15.017826539508583 -6.239992449261586 1.6131512573729034 1.1486063415491812 0.29870182473742146 0.6092405261836948 0.28395577550001194 0.2399195766808364 1.2394160180992349 0.09801448396299256 0.13478292490678764 5.754499421481608e-07 6.239992449261586 -0.8499045168117597 SPGS(ph)PPGPELPIETALDDR ddPTM_PC-9_AZD4547_30min_R2 2 SPGSPPGPELPIETALDDR 19 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3;B1AP52 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.023)PGS(0.977)PPGPELPIETALDDR;S(0.006)PGS(0.994)PPGPELPIETALDDR 123.92 2.6058e-05 8527100.0 13522.6 11421.0 16666.2 17588.800000000003 19031.4 20071.8 15129.400000000001 20019.8 16599.1 16552.8 True False 17822.505512446824 15112.6149001722 16445.19529849837 13533.973904251114 16389.218615876372 18816.70717299008 16475.887290468603 16926.19991923777 17476.494538265724 15973.291510280202 1.1157691262928804 0.9461177673021193 1.0295433028261243 0.8472877299923328 1.0260389103478444 1.1780106286096321 1.031464759775087 1.0596563587626437 1.094107280707804 1.0 13.963374009534895 -6.524275333593917 24.99835433831644 1.0769382120535733 0.9790713402185317 0.22551851160510472 0.0764741510025187 62.68519888316995 1122005.2935726123 0.024397281589719964 0.024573560811898 2.990368204792018e-07 6.524275333593917 -0.09786687183504161 SPGS(ph)PPGPELPIETALDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPGSPPGPELPIETALDDR 19 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3;B1AP52 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.076)PGS(0.924)PPGPELPIETALDDR;S(0.126)PGS(0.874)PPGPELPIETALDDR 129.42 3.6476e-05 11169700.0 13305.6 17548.0 18392.2 17479.8 19693.3 17875.7 20843.6 18581.300000000003 15670.5 13716.8 True False 15557.975282421048 19290.049469308167 18830.739800806932 16500.46347627621 15834.539234536918 16938.266823628637 18869.143313404104 18093.56056351473 15899.651416826624 16203.547257870949 0.9601586019915292 1.1904831184380282 1.1621368766434654 1.018324149254481 0.9772267135423213 1.045343130986383 1.1645069448751926 1.1166419473196338 0.9812451041609604 1.0 13.984022060012938 -8.27165062093541 24.036880990940613 0.9906225207397598 1.0820828460278158 0.1787565780611079 0.07589368537871195 835.2845229219923 1966193.9698737944 0.07347946258649504 0.019959668175528213 5.349945760999517e-09 8.27165062093541 0.09146032528805603 SPGS(ph)PPGPELPIETALDDR ddPTM_PC-9_Lapatinib_30min_R1 1 SPGSPPGPELPIETALDDR 19 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3;B1AP52 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.001)PGS(0.999)PPGPELPIETALDDR 83.25299999999999 0.0015965999999999999 3701500.0 2599.2 3259.0 4225.2 4213.2 4959.7 5483.3 4940.9 5056.0 4081.9 3909.9 True False 2562.1349313650967 3251.453985732364 3877.8203657436566 4523.052782823188 4667.98019714537 5248.792041196606 5196.71562599063 5290.920217835456 3622.1534376874192 4585.721005385734 0.5587201943502402 0.7090387709835966 0.84562937021012 0.9863340524883775 1.0179381152196187 1.1445947180458913 1.1332385070716924 1.1537815343806341 0.7898765392472316 1.0 12.162932868889486 -5.30251368709196 1.1247646106830957 1.0594969382857387 0.5153941745436925 0.7247048861428327 0.10044873007796491 0.4120355001766831 0.759086339076141 0.0339306699159558 0.21541242386819937 4.982947516181938e-06 5.30251368709196 -0.5441027637420461 SPGS(ph)PPGPELPIETALDDRER ddPTM_PC-9_AZD4547_30min_R2 1 SPGSPPGPELPIETALDDRER 21 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3;B1AP52 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.447)PGS(0.552)PPGPELPIETALDDRER 75.225 0.00069329 4583100.0 7555.9 7080.6 11981.0 15153.0 12887.0 9929.8 9260.7 10609.0 8920.7 8552.5 True False 9958.519027516677 9369.265481320317 11822.124111753661 11659.709961516248 11097.862495812127 9308.888036267646 10084.884359646945 8969.622820567318 9392.229990030006 8253.079578178395 1.2066427971744704 1.1352447765187168 1.4324500327140939 1.4127708149507217 1.34469350388375 1.1279290291688049 1.221954091695898 1.0868213174974712 1.138027314660044 1.0 13.010716835917027 -7.48356017973391 1.0169229128916026 1.0576623508678298 1.3022047598574629 0.4844502599392827 0.09783749904659232 0.5352325095900187 1.029772326675852 0.08600471431083433 0.041276967887888476 3.284277312612278e-08 7.48356017973391 0.2445424089896331 SPGS(ph)PPGPELPIETALDDRER ddPTM_PC-9_Lapatinib_30min_R1 1 SPGSPPGPELPIETALDDRER 21 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3;B1AP52 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.183)PGS(0.792)PPGPELPIET(0.026)ALDDRER 51.577 0.016637 3078500.0 4935.3 5174.6 8024.5 6613.6 6039.7 6485.4 4907.5 6196.9 7676.1 4557.6 True False 4864.921716976823 5162.618531626477 7364.75658546577 7099.986206322848 5684.456720507063 6208.034560205797 5161.586337418081 6484.83059689568 6811.536785083516 5345.375087379734 0.9101179313801108 0.9658103401976899 1.3777810658888527 1.3282484559569443 1.063434581780405 1.1613842730817479 0.9656172397713356 1.213166614295443 1.2742860274043901 1.0 12.384075470721285 -5.068097037230288 10.216320220812461 1.1744144232111304 0.923901677737648 0.3547486834112954 0.12774750804115223 0.5714131156155617 83.95420347301315 0.03380845952679547 0.08991081110010128 8.5487568113078e-06 5.068097037230288 -0.25051274547348246 SPGS(ph)PVCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGSPVCR 8 0 Q86VQ1;H7C0Q2;H7C2L5 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 S(0.247)PGS(0.753)PVCR 75.652 0.026068 5423600.0 21915.0 27315.0 26224.0 22438.0 29851.0 29117.0 25284.0 22349.0 22799.0 14048.0 True False 25624.77665902005 30026.652681453892 26849.279615073818 21180.871604977514 24001.910837196483 27590.053262450976 22888.91647969205 21762.362430722875 23132.392243529583 16594.791196093185 1.5441457717800477 1.8094022592175123 1.6179341636666562 1.2763566202606997 1.4463520844328015 1.6625730891357249 1.3792831864664048 1.311397183222544 1.3939550049280227 1.0 14.018442856374156 -11.311802048438754 0.08558555867905271 3.400619851458545e-11 2.081343165673741 0.6291355022276042 0.1321791293403568 67.47770068312798 0.864407636993738 18.916843145756005 5.191822494528102 4.8775075639296336e-12 11.311802048438754 2.0813431656397348 SPGS(ph)PVGEGTGSPPK ddPTM_PC-9_AZD4547_30min_R2 4 SPGSPVGEGTGSPPK 15 0 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5;A0A0A0MSR2 P35611 ADD1 Alpha-adducin 1 S(0.005)PGS(0.993)PVGEGT(0.002)GSPPK;SPGS(1)PVGEGTGSPPK;SPGS(1)PVGEGTGSPPK;SPGS(1)PVGEGTGSPPK 257.48 4.5481e-50 398844000.0 636952.0 636720.0 748703.0 814780.0 722378.0 771641.0 708491.0 839313.0 685329.0 726801.0 True False 839489.4865753645 842527.2882617671 738774.7090261508 626945.0592255145 622088.2838519267 723390.1662866937 771545.3264710701 709616.4613440301 721554.0918131162 701355.9182110069 1.1969521676194073 1.2012834944215698 1.0533520711004911 0.893904283041773 0.886979446097392 1.0314166423973308 1.1000767319952183 1.0117779616861207 1.028798749789736 1.0 19.41978723126517 -5.356678549542787 3.773212567906084 0.9942782362615945 1.2007772527738567 0.6430169447397543 0.06027944071219991 0.1562118978382121 4.039960579560358 0.018444770681423642 0.04289384700473421 4.398670700808268e-06 5.356678549542787 0.2064990165122622 SPGS(ph)PVGEGTGSPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 SPGSPVGEGTGSPPK 15 0 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5;A0A0A0MSR2 P35611 ADD1 Alpha-adducin 1 S(0.009)PGS(0.991)PVGEGTGSPPK;SPGS(1)PVGEGTGSPPK;SPGS(1)PVGEGTGSPPK;SPGS(1)PVGEGTGSPPK;S(0.001)PGS(0.999)PVGEGTGSPPK;S(0.003)PGS(0.996)PVGEGTGSPPK;SPGS(1)PVGEGTGSPPK 228.11 1.7008000000000003e-24 351625500.0 294412.0 339890.0 321370.0 365128.0 375672.0 278996.0 358674.0 264465.0 276260.0 256912.0 True False 344250.136697942 373632.0329452451 329032.6796025127 344671.061920948 302061.768384016 264364.9586156121 324697.80214511446 257523.07397383044 280299.77986742737 303488.1118857267 1.1343117677952523 1.2311257618088511 1.0841699121526196 1.1356987256579198 0.9953001668076944 0.8710883499619724 1.069886395640347 0.8485441896676217 0.9235939362691397 1.0 18.211280479354613 -6.309840950051367 2.66287341156799 0.9396032220001815 1.1535939267250277 0.6722092810548898 0.06741078184214504 0.16284546207935716 2.2805363176656104 0.021797529198787968 0.026565513111701505 4.899582219752618e-07 6.309840950051367 0.21399070472484616 SPGS(ph)PVGEGTGSPPK ddPTM_PC-9_Lapatinib_30min_R1 4 SPGSPVGEGTGSPPK 15 0 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5;A0A0A0MSR2 P35611 ADD1 Alpha-adducin 1 S(0.003)PGS(0.995)PVGEGT(0.001)GS(0.001)PPK;SPGS(1)PVGEGTGSPPK;S(0.006)PGS(0.994)PVGEGTGSPPK;S(0.008)PGS(0.992)PVGEGTGSPPK 210.08 1.5626e-14 382499000.0 555811.0 865386.0 931524.0 780476.0 925109.0 848034.0 861054.0 843855.0 908751.0 650193.0 True False 547885.033216747 863382.2518861585 854937.6925066275 837874.8086316142 870695.9074542726 811765.5626838079 905635.1629504202 883063.5839441349 806397.8928077327 762577.9937222849 0.7184642590358769 1.1321887846144487 1.1211150853350984 1.0987398214073705 1.1417794830457197 1.0645016894880868 1.187596770960891 1.1579977277258389 1.057462842418983 1.0 19.540525373182696 -4.759863154695183 24.999999783947942 1.1142461833811177 0.7184637720766985 0.8314642567394823 0.05235763738756709 14.262806675350234 226145.29802796643 0.012219279902219124 0.07528456753502093 1.7383484925228573e-05 4.759863154695183 -0.39578241130441916 SPGS(ph)TPT(ph)TPTSSQAPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-4;P35658-3;P35658-5 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 2 SPGS(0.623)T(0.395)PT(0.543)T(0.212)PT(0.184)S(0.036)S(0.007)QAPQK 177.04 0.00011593 14053000.0 23229.0 25765.0 24125.0 22975.0 31658.0 23183.0 31892.0 27711.0 20150.0 22357.0 True False 27161.210906337044 28322.77892504702 24700.23149457198 21687.785235954983 25454.842158854513 21967.242668660958 28870.95888191503 26983.615612231482 20444.655629945224 26410.147122085364 1.0284384551430086 1.0724203388235662 0.9352553539513048 0.8211913828309829 0.9638281089910332 0.8317728245554131 1.0931767531795318 1.0217139453065205 0.7741212320944807 1.0 14.688804717847782 -5.270470029158027 21.792950062623085 0.9305307477772161 1.0504293971294114 0.2085520069903467 0.0937360542556273 159.34013882653576 384530.57145468844 0.02463769497105289 0.05280969020719308 5.364508908609624e-06 5.270470029158027 0.1198986493521953 SPGS(ph)TPTT(ph)PTSSQAPQK ddPTM_PC-9_Lapatinib_30min_R1 1 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-4;P35658-3;P35658-5 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 2 S(0.007)PGS(0.801)T(0.19)PT(0.142)T(0.594)PT(0.214)S(0.041)S(0.011)QAPQK 99.055 0.034529000000000004 23444000.0 15106.0 25272.0 24443.0 23232.0 35227.0 31693.0 30906.0 33184.0 40229.0 30032.0 True False 14890.585669898883 25213.484236707052 22433.390892708554 24940.558779680116 33155.0171189467 30337.564269991413 32506.1614557806 34725.84978414792 35697.986389849626 35222.99118487539 0.42275187793513797 0.7158246187658708 0.6368962469701143 0.7080761156477106 0.9412890843064836 0.8613000557152636 0.9228677168604185 0.9858858835094919 1.0134853738707517 1.0 15.104229809568867 -4.619636517254222 0.3501810405632732 1.0305500111840773 4.4345033524959606e-17 0.8812782321367933 0.06344576500188862 2.369075324469919 0.21362354603854392 0.06031616332544253 1.0619911230385906 2.4008414625238397e-05 4.619636517254222 -1.0305500111840773 down SPGS(ph)TPTTPT(ph)SSQAPQK ddPTM_PC-9_AZD4547_30min_R2 1 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-4;P35658-3;P35658-5 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 2 S(0.011)PGS(0.751)T(0.237)PT(0.069)T(0.383)PT(0.427)S(0.099)S(0.023)QAPQK 116.04 0.0038691000000000003 16931000.0 38728.0 40349.0 44732.0 55757.0 46855.0 54962.0 46297.0 51433.0 51711.0 45954.0 True False 51042.69840755778 53391.02518229999 44138.82445263042 42903.08508706275 40349.99202617186 51525.21745144337 50417.3433108269 43485.21166276168 54444.337889901195 44345.164447309 1.1510318891298013 1.203987533877325 0.9953469561506813 0.9674805724994044 0.9099073716169389 1.161912873559545 1.1369298984274345 0.98060774392732 1.227740128342337 1.0 15.436489176111197 -5.254851806350183 24.895997825327882 1.0463076813859251 1.177509722721144 0.23145850511684396 0.09474886378150575 740.2700917055163 2797636.4011131837 0.024938535831974827 0.06289417095312057 5.560939800076712e-06 5.254851806350183 0.13120204133521884 SPGS(ph)TPTTPT(ph)SSQAPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-4;P35658-3;P35658-5 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 2 SPGS(0.768)T(0.232)PT(0.164)T(0.086)PT(0.61)S(0.117)S(0.023)QAPQK;SPGS(0.911)T(0.088)PT(0.003)T(0.05)PT(0.752)S(0.16)S(0.035)QAPQK 189.44 5.821199999999999e-41 0.0 19230.1 19315.9 20161.8 23930.1 27684.0 20007.3 25702.0 21655.6 18509.7 18647.9 True False 22485.376118212233 21233.4548976641 20642.533776052285 22589.374079430974 22259.51893125683 18958.081967161284 23267.320493634124 21087.16344600483 18780.369345587937 22028.616653304834 1.0207348228940591 0.9639032369505854 0.9370780789793897 1.025455862024909 1.0104819236534925 0.8606115520339361 1.056231576400121 0.9572622638036254 0.8525441992641158 1.0 14.427091279487028 SPGS(ph)TPTTPT(ph)SSQAPQK ddPTM_PC-9_Lapatinib_30min_R1 3 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-4;P35658-3;P35658-5 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 2 S(0.318)PGS(0.588)T(0.093)PT(0.01)T(0.031)PT(0.666)S(0.148)S(0.147)QAPQK;S(0.097)PGS(0.711)T(0.192)PT(0.012)T(0.163)PT(0.695)S(0.127)S(0.003)QAPQK;SPGS(0.889)T(0.11)PT(0.002)T(0.022)PT(0.45)S(0.45)S(0.076)QAPQK 174.35 6.867200000000001e-24 20161000.0 32712.8 52156.700000000004 56126.200000000004 46291.0 66616.8 72918.9 73342.1 74893.1 83466.0 64925.5 True False 32246.309473207202 52035.93436564812 51511.72048939736 49695.39456224915 62698.5307976679 69800.3286292582 77139.39507234863 78372.90683670361 74065.18014405508 76147.78616720928 0.42347008490042076 0.683354526570016 0.676470362201801 0.6526177196159769 0.823379561685368 0.9166429142928332 1.0130221632834069 1.029221081550661 0.9726504718261787 1.0 16.216514473622283 -6.2484492815010855 0.6959446583272872 1.0301554050170185 0.5167448891039484 0.8967686982137258 0.061852796623491385 0.24723727392986639 0.25550581245994586 0.03922412996319841 0.07304534598401509 5.643528446872862e-07 6.2484492815010855 -0.5134105159130701 SPGS(ph)TPTTPTS(ph)SQAPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-4;P35658-3;P35658-5 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 2 SPGS(0.859)T(0.141)PT(0.002)T(0.078)PT(0.381)S(0.476)S(0.063)QAPQK 112.3 0.0032624000000000004 9051800.0 12364.0 13338.0 13513.0 17637.0 16727.0 14744.0 15668.0 13402.0 16498.0 14672.0 True False 14456.980999868754 14662.108492228881 13835.201168337879 16648.85606992549 13449.464425774207 13970.798684671408 14183.813613503218 13050.211700592772 16739.252038850434 17331.9174565119 0.8341247317928472 0.8459599769626225 0.7982498879914615 0.9605893930489628 0.7759940271767803 0.8060734606961989 0.818363787451233 0.7529583344334232 0.9658049711378708 1.0 14.081143650433852 -8.397287883282681 5.5672478632238125 0.9977820767737035 0.8264127223163024 0.5942240123436489 0.052749980694482876 0.15077328913062454 5.773787275177405 0.05052568523809835 0.013128085285299433 4.006010808509277e-09 8.397287883282681 -0.1713693544574011 SPGS(ph)TPTTPTSSQAPQK ddPTM_PC-9_AZD4547_30min_R2 2 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-4;P35658-3;P35658-5 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 S(0.003)PGS(0.986)T(0.011)PTTPTSSQAPQK;SPGS(0.499)T(0.499)PT(0.001)TPTSSQAPQK 272.24 8.3546e-71 70254000.0 40861.0 39773.0 50148.0 55675.0 58385.0 47859.0 53245.0 53792.0 53737.0 50009.0 True False 53853.94803840161 52628.84444659393 49483.00475387889 42839.98892017537 50279.25054845897 44866.36916430681 57983.7018507674 45479.68241718891 56577.42811374016 48258.20013155492 1.1159543433363102 1.090567909767135 1.0253802383633264 0.8877245484371741 1.0418799377389654 0.9297149301465499 1.2015305521693753 0.9424239257412917 1.1723899349645552 1.0 15.558486488437081 -8.261923980969478 24.999878866669018 1.0861949480184954 1.0294109114784749 0.052333670205991 0.09667835233872894 150.12160108654388 7743343.072812079 0.07500012107944994 0.02383628332434854 5.471117211053453e-09 8.261923980969478 -0.05678403654002051 SPGS(ph)TPTTPTSSQAPQK ddPTM_PC-9_Lapatinib_30min_R1 3 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-4;P35658-3;P35658-5 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 S(0.116)PGS(0.83)T(0.053)PTTPTSSQAPQK;SPGS(0.851)T(0.048)PT(0.096)T(0.003)PT(0.001)S(0.001)SQAPQK;S(0.041)PGS(0.477)T(0.477)PT(0.005)TPTSSQAPQK 256.98 9.633e-58 94919000.0 109681.0 184586.0 184943.0 174081.0 150636.0 128740.0 122403.0 138928.0 134073.0 101250.0 True False 108116.92882696795 184158.60245792993 169737.7004406249 186883.49745719208 141775.88664177057 123234.09030759768 128740.42841752118 145383.1020615992 118972.28688871997 118750.92759285562 0.9104512362013125 1.550797170101511 1.4293589438103622 1.5737434750651624 1.1938928774338282 1.037752654279155 1.084121455109093 1.2242691910588988 1.0018640637201868 1.0 16.85757925717207 -6.4897304922016446 7.304665391207119 1.087524233792754 1.3845236798641702 0.3708203180266084 0.18067386367807012 0.24143767298208596 43.669608207124234 0.05593536894268668 0.06199576971476119 3.237945300314293e-07 6.4897304922016446 0.29699944607141626 SPGSGSQSS(ph)GWHEVEPGMPSPTTLK ddPTM_PC-9_AZD4547_30min_R2 1 SPGSGSQSSGWHEVEPGMPSPTTLK 25 0 A0A590UJA3;S4R3W2;A0A590UJU2;A0A590UK38;B1AKN5;A0A590UK09;B1AKN8;Q12857-2;Q12857-3;Q12857;Q12857-4 A0A590UJA3 NFIA Nuclear factor 1;Nuclear factor 1 A-type 1 S(0.291)PGS(0.07)GS(0.02)QS(0.105)S(0.515)GWHEVEPGMPSPTTLK 85.814 3.9936e-05 0.0 3328.2 4258.3 13828.0 31627.0 19479.0 16012.0 7070.5 22435.0 12032.0 15231.0 True False 4386.49836913948 5634.712199404893 13644.631684945312 24335.88378227905 16774.67708201476 15010.767108775372 7699.760802626552 18968.186255012504 12667.986956185165 14697.767325955587 0.2984465784400549 0.38337198259046107 0.9283472368520568 1.655753778283249 1.1413078401636858 1.0212957366842406 0.5238728190389247 1.2905488183579796 0.8618987275580338 1.0 13.843309397712543 -5.291152965280029 4.086038992935582 1.0746703751135873 0.3239615749562379 0.5230340457313858 0.2743479590548436 0.1626526882985066 6.2483403186514925 0.076211597582186 0.18644801088074323 5.1150164496395954e-06 5.291152965280029 -0.7507088001573494 SPGSNS(ph)KVPEIEVTVEGPNNNNPQTSAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGSNSKVPEIEVTVEGPNNNNPQTSAVR 29 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347 A0A494C1K3 GTF2I General transcription factor II-I 1 S(0.127)PGS(0.353)NS(0.52)KVPEIEVTVEGPNNNNPQTSAVR 98.98 4.5631e-11 32429000.0 4486.1 1042.4 1570.8 7232.4 5931.8 13773.0 5883.4 12697.0 12394.0 6407.4 True False 5245.508125486189 1145.882583018398 1608.2538292921745 6827.192075757164 4769.506371782591 13050.719634019213 5326.081759872659 12363.717203583523 12575.238802855625 7569.010899049509 0.6930242531616518 0.15139132421678692 0.21247873080670734 0.9019926337554224 0.6301360158407923 1.7242305247120306 0.7036694531040364 1.6334653719597783 1.6614111104576137 1.0 12.885889069117638 -6.356772682831334 1.3097479376889103 1.3545118549464814 0.3479208439145874 0.5479463279139449 0.3673186822008882 0.3152381715760009 1.1039556677313775 0.14573779571405884 0.1897364397158389 4.3977173926615653e-07 6.356772682831334 -1.006591011031894 SPGST(ph)PTTPT(ph)SSQAPQK ddPTM_PC-9_Lapatinib_30min_R1 1 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-4;P35658-3;P35658-5 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 2 S(0.036)PGS(0.27)T(0.693)PT(0.316)T(0.027)PT(0.355)S(0.256)S(0.046)QAPQK 116.04 0.00074002 7975700.0 19818.0 30932.0 33812.0 28093.0 42471.0 44870.0 44639.0 43672.0 49233.0 37905.0 True False 19535.391685823906 30860.37885445642 31032.107878094437 30159.052935500742 39972.93928119868 42951.014697078695 46950.188999695514 45701.160552474306 43687.86109352626 44456.828744762315 0.4394238688949551 0.6941650973719585 0.6980279240396896 0.6783896599699306 0.899140591217004 0.9661286220767371 1.0560849778387973 1.0279896664437316 0.9827030475868873 1.0 15.440117419291287 -6.05630445626295 0.7750812115750231 1.0353543547392876 0.5235684267743546 0.8940232902208688 0.06305993733097005 0.238492801100411 0.29069543936813874 0.03397231695439664 0.07750415313754869 8.784065059522536e-07 6.05630445626295 -0.511785927964933 SPGSTPT(ph)TPTSSQAPQK ddPTM_PC-9_AZD4547_30min_R2 2 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-4;P35658-3;P35658-5 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 SPGSTPT(0.948)T(0.052)PTSSQAPQK;SPGSTPT(0.928)T(0.066)PT(0.004)S(0.001)SQAPQK 225.6 1.3955e-28 17684200.0 50929.0 56941.0 62559.0 60495.0 53715.0 63679.0 51719.0 66496.0 50479.0 45436.0 True False 67123.36261099236 75346.06470805568 61729.426784675576 46548.812388433005 46257.59943839124 59697.14206343406 56321.890807021155 56220.57112606695 53147.21688507902 43845.29946964208 1.5309135397163318 1.7184525050450237 1.4078915535157022 1.06166026806734 1.055018439785533 1.3615402970338382 1.2845593823807204 1.2822485376110464 1.2121531276545954 1.0 15.420134563260895 -5.518040778226517 4.769350367692442 1.198831282225682 1.6165629735353215 0.6975002937576135 0.11773227765134926 0.10494210375724482 6.5122354853759585 0.0331352090872988 0.06485506689906269 3.0336063293341164e-06 5.518040778226517 0.4177316913096396 SPGSTPT(ph)TPTSSQAPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-4;P35658-3;P35658-5 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 SPGS(0.006)T(0.029)PT(0.701)T(0.204)PT(0.042)S(0.013)S(0.004)QAPQK 147.75 0.00019174 6395800.0 14912.0 18225.0 14912.0 19215.0 19989.0 19620.0 25423.0 22652.0 21137.0 18381.0 True False 17436.3070745748 20034.257555171043 15267.558634074921 18138.44584587051 16072.298942237132 18591.092660963976 23014.749393419217 22057.409001777894 21446.088637724664 21713.329796084072 0.8030231769297486 0.9226709004707402 0.7031422069971219 0.8353599386281931 0.7402042474911296 0.8562064333549071 1.059936435800365 1.015846450494934 0.987692299575001 1.0 14.406293363537284 -7.134872076073734 4.480225777267047 1.0163258810807074 0.8037135268372022 0.7596448694530095 0.057261058417154835 0.11145501537543681 3.558898208050614 0.02220288017865195 0.01703133517221079 7.330404225952197e-08 7.134872076073734 -0.21261235424350522 SPGSTPTT(ph)PTSSQAPQK ddPTM_PC-9_AZD4547_30min_R2 3 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-4;P35658-3;P35658-5 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 SPGSTPT(0.018)T(0.342)PT(0.047)S(0.249)S(0.342)QAPQK;SPGSTPT(0.048)T(0.95)PT(0.001)SSQAPQK;SPGSTPT(0.044)T(0.945)PT(0.008)S(0.003)S(0.001)QAPQK 221.34 1.2811000000000002e-22 30176100.0 78366.0 72742.0 81637.0 86392.0 81569.0 84341.0 71799.0 85458.0 65897.0 67598.0 True False 103284.75788593991 96254.42895265977 80554.44003933176 66475.65914309463 70244.55233342902 79067.1439371236 78188.97190690691 72252.42972947886 69380.1808886082 65231.41459522994 1.5833591610244282 1.475583958280408 1.2349025471727595 1.0190743149690284 1.0768515870659299 1.2121022428801569 1.1986398331552433 1.107632421860162 1.0636007408259032 1.0 15.99327929440202 -5.285542514059257 2.432474794182807 1.1096075350021743 1.5672269078095165 0.8673311324641779 0.06708631610562113 0.10763350471838523 1.2103276753181962 0.019589163123943112 0.06357739184431954 5.181523664291092e-06 5.285542514059257 0.4576193728073421 SPGSTPTT(ph)PTSSQAPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-4;P35658-3;P35658-5 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 SPGSTPT(0.008)T(0.851)PT(0.051)S(0.07)S(0.018)QAPQK;SPGSTPT(0.001)T(0.998)PT(0.001)SSQAPQK 189.52 2.4362e-42 6106000.0 24557.0 28473.0 30800.0 32282.0 38728.0 37207.0 48853.0 35663.0 34618.0 33811.0 True False 28714.015077141463 31299.611268498484 31534.38880965045 30473.3441996561 31139.526411274186 35255.79942081991 44225.29017490886 34726.88403807192 35124.22275917834 39940.666652271284 0.7189167703966853 0.7836527001664001 0.7895308579647156 0.7629653371828031 0.7796446334353658 0.8827043305952189 1.1072747122610667 0.8694618029390635 0.8794100275034079 1.0 15.285570792649292 -6.882788996801236 3.7815333734096215 0.9578158412170592 0.7685479303519849 0.6718244969337209 0.06487025443818907 0.1461982690997765 3.949510126137164 0.024342680935331113 0.021346217375584134 1.3098181472718159e-07 6.882788996801236 -0.18926791086507433 SPGSTPTT(ph)PTSSQAPQK ddPTM_PC-9_Lapatinib_30min_R1 3 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-4;P35658-3;P35658-5 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 SPGSTPT(0.009)T(0.987)PT(0.002)S(0.002)SQAPQK;SPGSTPT(0.006)T(0.991)PT(0.002)S(0.001)SQAPQK;SPGS(0.001)T(0.003)PT(0.124)T(0.671)PT(0.07)S(0.094)S(0.038)QAPQK 163.02 7.6536e-05 22084000.0 22002.5 28035.2 29883.0 29378.1 45981.0 51315.0 52515.0 56894.0 54604.0 58702.0 True False 21688.740315235664 27970.286216877572 27426.13509171582 31538.663476468664 43276.48798212419 49120.37707110748 55233.96974213155 59537.50294175841 48453.92251438884 68848.56248450176 0.31502096096948917 0.406258100496635 0.3983545059185457 0.4580874652766819 0.6285750409366354 0.7134553765325861 0.8022530572742904 0.8647602911848838 0.7037753696788676 1.0 16.071138911641988 -6.443138879273309 0.5008222098552042 0.9170845488041606 0.2599567224016508 0.911471517935686 0.06426875785436678 0.32458652853319514 0.16620703485103597 0.0552252370712831 0.10067860889724171 3.604633551328388e-07 6.443138879273309 -0.6571278264025098 down SPHQLLS(ph)PSSFSPSATPSQK ddPTM_PC-9_AZD4547_30min_R2 1 SPHQLLSPSSFSPSATPSQK 20 0 E9PIQ6;A0A3B3ITS5;Q14181 E9PIQ6 POLA2 DNA polymerase alpha subunit B 1 S(0.033)PHQLLS(0.952)PS(0.01)S(0.004)FSPSATPSQK 75.404 0.0013247 21479000.0 27950.0 39371.0 79012.0 104200.0 80631.0 68295.0 54159.0 87376.0 52493.0 86258.0 True False 36837.5186038845 52096.90580813236 77964.24925447634 80178.29987395201 69436.77744237032 64024.50285372301 58979.046080114764 73874.04690073433 55267.67281341652 83238.13367489167 0.4425557971754037 0.6258778700110033 0.9366410058998456 0.9632399999152956 0.8341943094684684 0.7691727340234162 0.7085580067240921 0.8875024419609019 0.6639705910427892 1.0 16.34495699757604 -5.012347315175657 3.6318858636827764 0.8368223737914507 0.45981603088368694 0.6109303421837406 0.10385329794732866 0.15117709697392345 4.21448291554317 0.027329445380849242 0.11318356267055303 9.7196960667645e-06 5.012347315175657 -0.3770063429077638 SPIIHS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 SPIIHSPK 8 0 E9PQ01;O94913;E9PKN0 E9PQ01 PCF11 Pre-mRNA cleavage complex 2 protein Pcf11 1 S(0.001)PIIHS(0.999)PK 61.48 0.037239 6474700.0 55195.0 44297.0 75022.0 89255.0 87983.0 74611.0 64161.0 80955.0 64356.0 75016.0 True False 72745.86187268005 58615.13897495213 74027.15926149592 68678.63872600356 75768.07914712794 69945.56237527113 69871.20470367331 68445.26491083312 67757.72677462205 72389.71267309348 1.0049198869070652 0.8097164197854149 1.0226198796477757 0.9487347882723495 1.046669151586371 0.9662362204853615 0.9652090348694494 0.9455109349573856 0.9360132023262872 1.0 16.143497069537133 -5.295019893309555 24.999866398762347 0.9773335591700573 0.9073179537816951 0.21281743851503 0.05498395117923421 804.226446136842 598725.3813818678 0.013570998933203033 0.0282522569006246 5.069674855709133e-06 5.295019893309555 -0.07001560538836216 SPIIHS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 SPIIHSPK 8 0 E9PQ01;O94913;E9PKN0 E9PQ01 PCF11 Pre-mRNA cleavage complex 2 protein Pcf11 1 S(0.001)PIIHS(0.999)PK 65.179 0.029745999999999998 8805800.0 82052.0 55110.0 84151.0 68857.0 93402.0 82637.0 70541.0 75635.0 92971.0 64897.0 True False 80881.923433506 54982.3961809483 77232.42961225384 73920.97348021842 87908.27799539719 79102.80814625576 74193.26782023621 79149.27821914248 82499.62695196776 76114.35998018307 1.0626368461163465 0.7223656113677284 1.0146893389415856 0.9711830132903212 1.1549499728866504 1.0392626065153903 0.9747604504531467 1.0398731361565619 1.083890437670988 1.0 16.21588104244778 -5.492571291663859 24.461055554654585 1.037941464758707 0.8865077292748945 0.28165032754610564 0.09146582022034096 571.4565674095365 461219.5235544254 0.02257474482190952 0.04688496618833581 3.2168344295016643e-06 5.492571291663859 -0.15143373548381256 SPITS(ph)SPPK ddPTM_PC-9_AZD4547_30min_R2 2 SPITSSPPK 9 0 G3V5T8;Q52LA3 G3V5T8 LIN52 Protein lin-52 homolog 1 SPIT(0.061)S(0.47)S(0.47)PPK;SPIT(0.022)S(0.489)S(0.489)PPK 93.111 0.0090455 22405000.0 73370.0 83086.0 69044.0 69990.0 68447.0 75764.0 85340.0 74712.0 75301.0 81345.0 True False 96700.13380919502 109941.92466471466 68128.43144745177 53854.88683472063 58944.315531221604 71026.46510300132 92935.0946745138 63166.97711096473 79281.25712996176 78497.13630949114 1.23189377798363 1.4005851656963124 0.8679097690754144 0.6860745419092315 0.750910393709415 0.9048287420698361 1.1839297462788712 0.8047042233733969 1.0099891646668366 1.0 16.260352402885495 -5.266502906030493 24.78864708023479 0.8912673943342703 1.316239487494116 0.5841315955864037 0.13993719122373544 238.90819796436446 1169588.1936984197 0.038761320157012315 0.08486508730431544 5.413736253325678e-06 5.266502906030493 0.42497209315984563 SPITS(ph)SPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPITSSPPK 9 0 G3V5T8;Q52LA3 G3V5T8 LIN52 Protein lin-52 homolog 1 S(0.001)PIT(0.005)S(0.637)S(0.357)PPK;SPIT(0.018)S(0.491)S(0.491)PPK 104.43 0.0027033 46641000.0 75368.0 92427.0 68284.0 77856.0 81458.0 52823.0 81483.0 60092.0 60311.0 55908.0 True False 88126.31381414643 101602.54173123678 69912.14952851206 73493.98073255747 65496.88965114567 50052.86889042304 73764.34035416669 58514.648672736934 61192.93427779777 66043.67783251543 1.3343641163902444 1.538414350407581 1.0585744438068234 1.1128087221147156 0.9917208096321286 0.7578752506387583 1.116902370901127 0.8859992446381943 0.9265524920187065 1.0 16.01113284266841 -5.481676255324269 1.6770967622366775 0.9506664994363343 1.4524274702627633 0.7063767428216808 0.11574889604586423 0.20667143624154558 1.09651522238967 0.033686323999912754 0.10592114107006041 3.2985551123077075e-06 5.481676255324269 0.501760970826429 SPITSS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 1 SPITSSPPK 9 0 G3V5T8;Q52LA3 G3V5T8 LIN52 Protein lin-52 homolog 1 SPIT(0.012)S(0.224)S(0.764)PPK 90.149 0.008796600000000002 31178000.0 42236.0 41814.0 34899.0 40849.0 38087.0 35881.0 46312.0 40895.0 33304.0 38265.0 True False 41633.70689486622 41717.1822520445 32029.738934035766 43853.17172826932 35846.797541923064 34346.45327269624 48709.80875364367 42795.13099453741 29552.95281333247 44879.05426509246 0.9276868146316862 0.9295468216782966 0.7136901491916895 0.977141173012171 0.7987422669422245 0.7653114316941251 1.0853572908627627 0.953565793560495 0.6585021297188778 1.0 15.453754653948984 SPLEHS(ph)SPEKEAPSPEK ddPTM_PC-9_Lapatinib_30min_R1 2 SPLEHSSPEKEAPSPEK 17 1 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 S(0.182)PLEHS(0.409)S(0.409)PEKEAPSPEK;S(0.001)PLEHS(0.952)S(0.046)PEKEAPSPEK 81.52600000000001 0.011125 3316200.0 35646.0 31135.0 29360.0 22746.0 31586.0 33476.0 38499.0 35586.0 37348.0 28037.0 True False 35137.68150332422 31062.90882042869 26946.134132877443 24418.816718431633 29728.173580465293 32044.30951636745 40492.28984294625 37239.45547308001 33141.47494812458 32883.1580930458 1.068561644958159 0.9446449374641404 0.8194509194229757 0.7425934166461882 0.9040546986498924 0.9744900239111842 1.23139905626977 1.1324780718356697 1.0078555975173629 1.0 15.005061241415218 -7.012875961470358 4.539537986223336 1.1052564691758082 0.8886551043342263 0.46075625598915104 0.0997694781749826 0.1786364524683499 9.36572541899666 0.04049232365311096 0.03303277448135814 9.707871934753998e-08 7.012875961470358 -0.21660136484158188 SPLEHSS(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 1 SPLEHSSPEK 10 0 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 SPLEHS(0.107)S(0.893)PEK 72.29 0.017537999999999998 4038600.0 30974.0 47193.0 40022.0 27441.0 34098.0 54873.0 44313.0 60504.0 56378.0 41719.0 True False 40823.08770077707 62447.21434058546 39491.28213008974 21114.90140922374 29364.08127432308 51441.78263551276 48256.771154344184 51154.49704360493 59358.0259820318 40258.430508275305 1.0140258123670691 1.5511586902959158 0.9809444042278829 0.5244839687648398 0.7293896186113654 1.2777890738919557 1.1986749246080217 1.270653038326715 1.4744247411689457 1.0 15.297003308836405 -6.796568752783473 24.979386291116 1.2583723376217812 0.9698107056363925 0.21941146678374068 0.2671496287144478 317.6510909718227 225869.4488639974 0.10487761579590295 0.09249703650288545 1.5974646157994854e-07 6.796568752783473 -0.28856163198538876 SPLGEAPPGT(ph)PPCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPLGEAPPGTPPCR 14 0 M0QXZ5;Q96B54 M0QXZ5 ZNF428 Zinc finger protein 428 1 SPLGEAPPGT(1)PPCR 109.55 0.0014161 7068300.0 14734.0 14532.0 13411.0 13706.0 17783.0 15718.0 16094.0 13766.0 14246.0 12701.0 True False 17228.175190235066 15974.640921357786 13730.76910150073 12938.097255451536 14298.548806333629 14893.720410042395 14569.459809530294 13404.657086282654 14454.320799215857 15003.590758939317 1.148270135265474 1.0647211842831628 0.9151655308459926 0.862333388275261 0.953008452180981 0.9926770630669555 0.9710648633127797 0.8934299329842758 0.9633907663473026 1.0 13.873020196948275 -5.063172638785897 3.307668914691847 0.9405255487622323 1.1396073607017896 0.7227925254125002 0.04164106060300643 0.1284906032960315 2.665287615478678 0.011513445708327626 0.04478761011411562 8.646241489568487e-06 5.063172638785897 0.19908181193955732 SPLGEAPPGT(ph)PPCR ddPTM_PC-9_Lapatinib_30min_R1 2 SPLGEAPPGTPPCR 14 0 M0QXZ5;Q96B54 M0QXZ5 ZNF428 Zinc finger protein 428 1 SPLGEAPPGT(1)PPCR;S(0.001)PLGEAPPGT(0.999)PPCR 111.81 0.00089063 18952900.0 76575.0 77192.0 69719.0 63663.0 70450.0 71060.0 52793.0 58776.0 78159.0 59504.0 True False 75483.02645786469 77013.26666666252 63986.97294312275 68344.98939354233 66306.2695100292 68020.92944895066 55526.36322186711 61506.94753233723 69355.91036924257 69789.18711590391 1.0815862682639448 1.1035128771275278 0.9168608431683692 0.9793062825052955 0.9500937358664118 0.9746628705673762 0.7956298893358722 0.8813248881977694 0.9937916350001073 1.0 16.09071590734998 -5.260849796334653 24.998987368365444 0.9305724295243204 1.092549586832304 0.5281476497371552 0.058804846561038446 38.67083830037362 1639594.278370506 0.01591893292728214 0.03729150495604718 5.484666229893677e-06 5.260849796334653 0.16197715730798368 SPLLAGGS(ph)PPQPVVPAHK ddPTM_PC-9_AZD4547_30min_R2 2 SPLLAGGSPPQPVVPAHK 18 0 Q8NFH5-2;Q8NFH5;C9IYQ7;F8WCF5;F8WEL4;C9JIY9 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 S(0.005)PLLAGGS(0.995)PPQPVVPAHK;S(0.001)PLLAGGS(0.999)PPQPVVPAHK 110.98 0.00012057 196007000.0 430770.0 361790.0 478190.0 470330.0 446700.0 482040.0 441120.0 521630.0 377190.0 455350.0 True False 567745.8994273832 478731.54231094464 471848.8881562047 361902.68502606364 384683.4156032656 451897.9625976809 480378.82543732837 441024.0693649284 397127.49335135357 439408.33509775286 1.2920690257299734 1.089491263756851 1.0738278054084591 0.8236136097544737 0.8754577118289918 1.0284237382459975 1.0932401301182897 1.0036770678617557 0.9037777885187515 1.0 18.74520271081189 -4.821311114177346 1.5691065951135135 0.9696164242010946 1.3898071166362673 0.6063242439282686 0.07956081123529866 0.7386429457339193 1.8503249485618813 0.024899724336933115 0.47148400494102594 1.5089987701553086e-05 4.821311114177346 0.4201906924351727 SPLLAGGS(ph)PPQPVVPAHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPLLAGGSPPQPVVPAHK 18 0 Q8NFH5-2;Q8NFH5;C9IYQ7;F8WCF5;F8WEL4;C9JIY9 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 S(0.046)PLLAGGS(0.954)PPQPVVPAHK;S(0.037)PLLAGGS(0.963)PPQPVVPAHK;S(0.001)PLLAGGS(0.999)PPQPVVPAHK 81.884 0.0016561 168729800.0 127509.2 138994.0 143912.0 141103.0 164347.0 141010.0 146013.0 140109.0 133137.0 117558.0 True False 149093.9891385042 152792.40574065567 147343.40786929926 133197.45637209827 132144.38512481112 133615.18736608207 132181.59159742447 136431.28720775645 135083.87675454206 138870.33481138403 1.0736201460233108 1.1002523033315994 1.0610142768750683 0.9591498180875652 0.9515666920821627 0.9621578830897212 0.9518346144765596 0.9824365109586556 0.9727338595245355 1.0 17.083378921190473 -5.686538765345432 4.2403199562201666 0.9659563734962843 1.0852861221992134 0.913254160498211 0.015582025296370738 0.05230837963766834 1.7891120152067153 0.00426873038272596 0.007542243534608989 2.058075177510224e-06 5.686538765345432 0.11932974870292912 SPLLAGGS(ph)PPQPVVPAHK ddPTM_PC-9_Lapatinib_30min_R1 2 SPLLAGGSPPQPVVPAHK 18 0 Q8NFH5-2;Q8NFH5;C9IYQ7;F8WCF5;F8WEL4;C9JIY9 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 S(0.01)PLLAGGS(0.99)PPQPVVPAHK;S(0.001)PLLAGGS(0.999)PPQPVVPAHK 143.14 0.0001115 158947000.0 421210.0 411770.0 499130.0 436370.0 532900.0 438350.0 431690.0 452710.0 474120.0 414980.0 True False 415203.46815954655 410816.5718640729 458093.4580975187 468462.10548764764 501555.8697217105 419602.7923437587 454040.79592460743 473744.5592991082 420719.61289506376 486708.7400739082 0.8530840602872606 0.8440706690446717 0.9412065582137601 0.9625101563134253 1.030505163407478 0.8621229860800131 0.9328798900460673 0.9733635751582531 0.8644176244527194 1.0 18.892699156487105 -5.270001454348731 9.063887239076006 0.9451255102329803 0.848486958972847 0.3771414664430627 0.050009190314416106 0.15982784050806428 142.409229993068 0.012884026554490988 0.02891759388372658 5.370299979817485e-06 5.270001454348731 -0.09663855126013332 SPLLAGGS(ph)PPQPVVPAHKDK ddPTM_PC-9_AZD4547_30min_R2 2 SPLLAGGSPPQPVVPAHKDK 20 1 Q8NFH5-2;Q8NFH5;C9IYQ7;F8WCF5;F8WEL4;C9JIY9 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 S(0.018)PLLAGGS(0.982)PPQPVVPAHKDK;S(0.002)PLLAGGS(0.998)PPQPVVPAHKDK 105.72 6.574e-05 20040100.0 110121.0 52055.9 116524.0 302388.0 210285.0 115511.1 88943.7 108694.0 73190.1 143518.0 True False 145137.1873409076 68881.95166639297 114978.81562457106 232677.11844802854 181090.55753331629 108288.17265666135 96859.51699322184 91897.83983964023 77058.77926544943 138493.4785034796 1.0479712756818444 0.4973660305937246 0.8302110457979598 1.6800583028332459 1.3075746200480225 0.7819008795705904 0.6993796245127043 0.6635535538038445 0.5564072770654926 1.0 17.079458517482365 -6.932242204500245 8.424660750408897 0.7072314641468224 1.0605916785835636 0.22938273022883282 0.30425155193543707 0.4603061012104128 51.411355532184764 0.11995454278943798 0.10574067250082483 1.1688473471739972e-07 6.932242204500245 0.35336021443674126 SPLLAGGS(ph)PPQPVVPAHKDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPLLAGGSPPQPVVPAHKDK 20 1 Q8NFH5-2;Q8NFH5;C9IYQ7;F8WCF5;F8WEL4;C9JIY9 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 S(0.009)PLLAGGS(0.991)PPQPVVPAHKDK 61.523999999999994 0.0049098 6422400.0 98621.0 30814.0 53712.0 125660.0 118460.0 192190.0 109080.0 189460.0 147620.0 98027.0 True False 115315.58744646226 33873.010277368485 54992.697783894306 118619.67759521687 95248.61337222505 182111.21806884138 98747.15272918905 184486.8757494632 149778.66323039783 115798.51911869503 0.9958295522610462 0.2925167829015861 0.47489983639191496 1.0243626472772949 0.8225374045983607 1.5726558461613396 0.8527497025067471 1.5931712871074084 1.2934419573783382 1.0 16.82125727807678 -6.219720704963923 1.4930920694782222 1.2658505429878995 0.572546261588281 0.4514698766633073 0.29581940717134175 0.3296005341659314 1.4687923107040004 0.10500523988394153 0.14963761278652749 6.029472171271531e-07 6.219720704963923 -0.6933042813996184 SPLLAGGS(ph)PPQPVVPAHKDK ddPTM_PC-9_Lapatinib_30min_R1 1 SPLLAGGSPPQPVVPAHKDK 20 1 Q8NFH5-2;Q8NFH5;C9IYQ7;F8WCF5;F8WEL4;C9JIY9 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 S(0.176)PLLAGGS(0.824)PPQPVVPAHKDK 68.88 0.0020611 7356900.0 189430.0 39127.0 66514.0 47773.0 39471.0 53194.0 21655.0 23824.0 67249.0 29913.0 True False 186728.6934627924 39036.40383545572 61045.47567146486 51286.38578605622 37149.39338297173 50919.01662127047 22776.189941271245 24930.950013787977 59674.70945663579 35083.42219343293 5.3224195870420274 1.112673775671825 1.740009151185132 1.4618410228993062 1.0588873906926193 1.4513697193086743 0.6492009193314839 0.7106191031288465 1.7009375290591224 1.0 15.098501861103175 -4.760614609096849 24.99999879194699 1.2102667261336064 5.322424367652557 0.9222272364864389 0.3583156088487806 5.215691923717774 158000.74076389836 0.09244349185966655 0.54187192823622 1.7353432502188084e-05 4.760614609096849 4.112157641518951 SPLLNS(ph)PTVAK ddPTM_PC-9_AZD4547_30min_R2 1 SPLLNSPTVAK 11 0 O43365 O43365 HOXA3 Homeobox protein Hox-A3 1 S(0.012)PLLNS(0.984)PT(0.004)VAK 101.62 0.0036564 2617000.0 13094.0 13497.0 18354.0 25141.0 19926.0 21311.0 17197.0 22808.0 16830.0 20104.0 True False 17257.619627880646 17859.641301779542 18110.613967709443 19345.130874577975 17159.618847796402 19978.41980109366 18727.499684996666 19283.547675699807 17719.599440874023 19400.165079181348 0.889560452575741 0.9205922335653232 0.9335288588417351 0.9971632094686436 0.884508908958238 1.0298066907962988 0.9653268211152218 0.9939888447853114 0.9133736423660245 1.0 14.24378130814242 -3.5778395733461257 0.5187271843561265 0.9736257951848638 0.6263792268962163 0.2946031521735323 0.04080591401246029 17.050388057508925 1.339436010163433 0.021466552880867712 4.724235987624232 0.00026433850329097436 3.5778395733461257 -0.34724656828864753 SPLLNS(ph)PTVAK ddPTM_PC-9_Lapatinib_30min_R1 2 SPLLNSPTVAK 11 0 O43365 O43365 HOXA3 Homeobox protein Hox-A3 1 S(0.007)PLLNS(0.987)PT(0.007)VAK;S(0.001)PLLNS(0.89)PT(0.11)VAK 110.51 0.0019275 20258700.0 118884.0 95383.0 88717.0 84052.0 120441.0 119810.0 116045.0 115637.0 127786.0 110633.0 True False 117188.69235934432 95162.14652381402 81423.03071752352 90233.4644692526 113356.89717611663 114686.00559075095 122053.24228745421 121009.91717362298 113393.39503376475 129755.76664079406 0.9031482406771217 0.7333943530020799 0.6275099197936136 0.6954100523258286 0.8736174130119797 0.8838605678947504 0.9406382887423961 0.9325976047647854 0.8738986942112127 1.0 16.985439131087055 -6.415339160674601 3.5583581421012815 0.9203036010187837 0.7319114307704944 0.5952123250620436 0.07240321770729222 0.18128989640739732 4.214101448163416 0.024730489875802324 0.02796588454163826 3.842915537573217e-07 6.415339160674601 -0.18839217024828936 SPLLNSPT(ph)VAK ddPTM_PC-9_Lapatinib_30min_R1 1 SPLLNSPTVAK 11 0 O43365 O43365 HOXA3 Homeobox protein Hox-A3 1 S(0.159)PLLNS(0.269)PT(0.573)VAK 113.54 0.0037914999999999997 5369600.0 28332.0 26530.0 23795.0 20201.0 32551.0 33059.0 31200.0 30729.0 32893.0 27558.0 True False 27927.98048454753 26468.571414998336 21838.66695135624 21686.648928560517 30636.414177728304 31645.143634292945 32815.383337227526 32156.781521729783 29188.243961354357 32321.363581273185 0.8640718518673155 0.8189187732888249 0.6756728222942129 0.6709694927947173 0.9478688639076747 0.9790782358151486 1.0152846198679741 0.9949079481399492 0.9030635074525711 1.0 14.980200443680094 -6.365636260369654 5.778147093573397 0.9782190012354905 0.7566704977219048 0.7501925438244869 0.06117296361501042 0.12423998299571257 5.760825828134928 0.020891989924865507 0.023729913959089483 4.3088734541770834e-07 6.365636260369654 -0.2215485035135858 SPMFPALGEAS(ph)SDDDLFQSAKPK ddPTM_PC-9_AZD4547_30min_R2 1 SPMFPALGEASSDDDLFQSAKPK 23 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;Q5SRD0;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21D;FAM21A WASH complex subunit FAM21C;Putative WASH complex subunit FAM21;WASH complex subunit FAM21A 1 S(0.021)PMFPALGEAS(0.489)S(0.489)DDDLFQSAKPK 67.866 0.0021339 1781400.0 10361.0 8672.8 8172.1 8887.1 9056.9 12929.0 9011.2 12628.0 11552.0 11056.0 True False 13655.58247781208 11476.11299415231 8063.732614444714 6838.316399326279 7799.505768473715 12120.547586145187 9813.179342992491 10676.63276257179 12162.61513612458 10668.932805184495 1.2799389336463196 1.0756570693345797 0.7558143594761604 0.640955991025011 0.7310483542162342 1.1360599797062447 0.9197901535403656 1.0007217176757879 1.1400029748255833 1.0 13.381128252650024 -6.773554877437621 24.996618941962108 1.0318897436645096 0.8845928403883944 0.13144471739929253 0.18149862641627398 535.0580777047496 1103921.768541137 0.07096129516150036 0.06303890128151164 1.684399572647069e-07 6.773554877437621 -0.14729690327611522 SPMFPALGEASS(ph)DDDLFQSAKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPMFPALGEASSDDDLFQSAKPK 23 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;Q5SRD0;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21D;FAM21A WASH complex subunit FAM21C;Putative WASH complex subunit FAM21;WASH complex subunit FAM21A 1 SPMFPALGEAS(0.436)S(0.564)DDDLFQSAKPK 88.471 3.8576e-05 1905200.0 3519.8 5605.0 5079.5 4762.4 6118.7 3286.5 5338.6 3473.3 3706.4 3933.6 True False 4115.632620781141 6161.427357845471 5200.614544111024 4495.57816790912 4919.784658455466 3114.150154447405 4832.889159883089 3382.1295552655497 3760.5990881800985 4646.730541639534 0.8857050315056567 1.3259704436555295 1.1191986489227455 0.967471241903112 1.0587626319987966 0.6701809210887921 1.0400622796125965 0.727851448444913 0.8093000130911882 1.0 12.18200027177205 -6.300736528816529 1.5790713903106017 0.8481040285796155 1.1217765541692455 0.3134904033950715 0.15349923939800947 0.4093104616771212 2.032163065044947 0.05454728462476647 0.07168280343338043 5.003379803733977e-07 6.300736528816529 0.27367252558962996 SPNPS(ph)TPR ddPTM_PC-9_AZD4547_30min_R2 1 SPNPSTPR 8 0 O76021;J3QSV6;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 S(0.001)PNPS(0.826)T(0.174)PR 79.20100000000001 0.021047 15554000.0 25195.0 26342.0 34937.0 42278.0 39406.0 41442.0 29083.0 43342.0 38552.0 47501.0 True False 33206.485911444375 34856.53635411403 34473.71255256973 32531.460288588663 33935.15709707243 38850.62518872526 31671.330658763596 36644.48980007809 40589.7800145321 45838.004448179134 0.7244313165723659 0.7604287484530464 0.75207708030883 0.7097049856384169 0.7403279768742304 0.8475636244733721 0.6909404333814035 0.7994346665223065 0.885504953873368 1.0 15.48425661746227 -8.437330885269365 1.7590495873246383 0.9982399630774329 0.7487437160961957 0.800782956798541 0.04040578318558216 0.14252069545692125 0.9489193006464373 0.03785658418679805 0.010916916503255302 3.6531635413611152e-09 8.437330885269365 -0.24949624698123718 SPNPS(ph)TPR ddPTM_PC-9_Lapatinib_30min_R1 1 SPNPSTPR 8 0 O76021;J3QSV6;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 SPNPS(0.595)T(0.405)PR 75.509 0.026271 13965000.0 32702.0 30263.0 32082.0 31869.0 39470.0 33737.0 29778.0 29415.0 26376.0 32129.0 True False 32235.663483187673 30192.927882853186 29444.34180010129 34212.75257186749 37148.45220100567 32294.14715478817 31319.759135126973 30781.72828473695 23405.25712840673 37682.45484079854 0.8554555062661771 0.8012463097325471 0.7813806697174649 0.9079226052657686 0.9858288786638519 0.8570075195797359 0.83114964955036 0.8168716293772288 0.6211181630095398 1.0 15.201605332591562 -13.81497930344196 15.815316573779313 0.9968020686255966 0.8432041942951405 0.0 0.10256673828045859 0.0 0.0 0.0 0.023635546745440245 1.5311604282908806e-14 13.81497930344196 -0.15359787433045613 SPNPST(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 SPNPSTPR 8 0 O76021;J3QSV6;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 SPNPS(0.112)T(0.888)PR;SPNPS(0.001)T(0.999)PR;S(0.001)PNPS(0.007)T(0.992)PR 119.34 0.00088779 94384800.0 58684.2 58356.9 90094.0 115780.0 97749.0 93431.0 83777.0 111356.0 95752.0 116421.0 True False 77344.55489281139 77219.62669362222 88899.29469362617 89088.70978316857 84178.23862055846 87588.74480014935 91232.99070244622 94148.48890631487 100813.2552384176 112345.13622579438 0.6884548587609716 0.687342855131922 0.7913052374154755 0.7929912480066391 0.749282447362694 0.7796398468386834 0.8120777967555588 0.8380290599950194 0.8973530908877114 1.0 16.777578141501877 -14.101120854265568 0.03591484816699597 2.241813045931482 2.3934240770278797e-08 0.9057894709042051 0.027312616994559554 289.33692513856477 0.831348044335635 42.626166047491175 15.465901720968235 7.922808260872976e-15 14.101120854265568 -2.241813021997241 SPNPST(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPNPSTPR 8 0 O76021;J3QSV6;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 SPNPS(0.005)T(0.995)PR;SPNPS(0.005)T(0.995)PR;SPNPS(0.102)T(0.898)PR 97.59700000000001 0.014094 153107000.0 82683.0 84665.0 118757.0 118884.0 153491.0 118056.0 114740.0 135062.0 107176.0 101658.0 True False 96679.59883631085 93069.9816685078 121588.61726843052 112223.31490712817 123415.54039436262 111864.93553428954 103870.99655433753 131516.76561001784 108743.24624292828 120087.79067571495 0.8050743401332482 0.7750161872811364 1.0124977450602652 0.9345106132410745 1.0277109746121813 0.9315263017567673 0.8649588436082628 1.0951718311244953 0.9055312420275806 1.0 16.873729954148196 -5.2561576344704495 24.930984018144052 0.970342901871479 0.7900452424266875 0.5678509936559726 0.06330775297870964 282.22250945175176 1332140.3479683327 0.015572938290462218 0.038701459495635464 5.544244387779059e-06 5.2561576344704495 -0.18029765944479148 SPNPST(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 SPNPSTPR 8 0 O76021;J3QSV6;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 SPNPS(0.013)T(0.987)PR;SPNPS(0.019)T(0.981)PR;SPNPST(1)PR 123.96 0.008084899999999999 175838000.0 100189.0 116389.0 116755.0 110962.0 132327.0 108920.0 111017.0 106213.0 117083.0 116521.0 True False 98760.28648758776 116119.50842141859 107155.8545873334 119122.51563838065 124543.7860248917 104261.74550492129 116764.91704964722 111148.0437296196 103895.87960135132 136661.49959552693 0.7226635649388139 0.8496870644994686 0.7840968736950749 0.8716611188296931 0.9113304507377742 0.7629196651105231 0.8544097452115845 0.8133091182123805 0.7602424963054624 1.0 17.06024733723541 -11.919909067989549 2.3241976782534057 2.517201583379602 0.8187757159886232 0.5016705210634713 0.055321452211091984 10038864.816896897 1308957.7538174693 79761475.23107903 0.014115551771567751 1.202516189526997e-12 11.919909067989549 -1.698425867390979 SPPAS(ph)PESWK ddPTM_PC-9_AZD4547_30min_R2 2 SPPASPESWK 10 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 S(0.021)PPAS(0.978)PES(0.001)WK;S(0.468)PPAS(0.532)PESWK 114.24 0.0012243 29278000.0 93792.0 62406.0 78556.0 131830.0 132515.0 114761.0 87088.0 116881.0 84682.0 117798.0 True False 123615.90500520697 82577.51908415605 77514.2961124215 101438.63025319665 114117.579625401 107584.9765282394 94838.66328818894 98819.72710818426 89158.11763827057 113673.92787492056 1.0874604873443445 0.7264420314130345 0.6819003931817438 0.8923649613376003 1.0039028452590169 0.9464349349009823 0.8343044448375468 0.8693262294667877 0.7843321622208252 1.0 16.79454187168549 -4.738681130804475 24.77219209455769 0.8576643180036366 1.087461535906926 0.3074285543348545 0.10242122107323462 2364.108201987751 2573166.4903077777 0.02738461839815999 1.4685169561145697 1.8252353410629108e-05 4.738681130804475 0.22979721790328933 SPPAS(ph)PESWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPPASPESWK 10 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 SPPAS(0.993)PES(0.007)WK;S(0.008)PPAS(0.992)PES(0.001)WK 111.94 0.0015236 11783700.0 25245.0 29252.0 25412.0 51069.0 77282.0 101273.0 108421.0 104663.0 98167.0 91294.0 True False 29518.479888522055 32155.945240266836 26017.918455546685 48207.76949793192 62139.14687347885 95962.06559907272 98150.57797993546 101915.70714961523 99602.50666128202 107844.8795170934 0.2737123915451487 0.29816849334205175 0.2412531644715023 0.44701027729639214 0.5761900532665513 0.8898156873907281 0.9101088379850116 0.9450212898931526 0.9235719591628366 1.0 16.718598153293378 -6.488722363481739 1.3200194144831539 0.9535965350733213 0.26932698908690855 0.9818439440649834 0.040167610795891935 0.048483469177394434 0.17445859730439392 0.016275466507553685 0.018778114022976942 3.245470280238327e-07 6.488722363481739 -0.6842695459864128 down SPPAS(ph)PESWK ddPTM_PC-9_Lapatinib_30min_R1 2 SPPASPESWK 10 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 SPPAS(1)PESWK;S(0.034)PPAS(0.903)PES(0.062)WK 116.74 0.0010155 19763600.0 44483.0 35787.0 37308.0 41187.0 72538.0 90105.0 91144.0 85239.0 108274.0 100513.0 True False 43848.66426281685 35704.13740024674 34240.6802530447 44216.02937580427 68271.45745519504 86251.41919501398 95862.99034898281 89199.51512026823 96079.04194423374 117886.53812484613 0.3719565012281514 0.30286865632134147 0.29045454042244057 0.3750727613103532 0.5791285293567029 0.7316477399961528 0.8131801295874888 0.7566556499080727 0.8150128375343633 1.0 16.847039455779246 -6.548665496838462 1.3584294253258875 0.833342727939364 0.31045082329545975 0.9326118937792961 0.06254804325001714 0.09831186081080777 0.37577433599140114 0.026232800615391683 0.02860362520323499 2.8270565977346475e-07 6.548665496838462 -0.5228919046439042 down SPPGQVTEAVK ddPTM_PC-9_Lapatinib_30min_R1 2 SPPGQVTEAVK 11 0 P15121;E9PCX2;E9PEF9 P15121 AKR1B1 Aldose reductase 0 ; 117.09 0.0055124 25016000.0 88104.0 95304.0 98683.0 92040.0 97409.0 80551.0 92194.0 78945.0 85854.0 95597.0 False True 86847.62080370505 95083.32944346045 90569.66466739599 98808.92863643948 91679.5941334625 77106.02150355221 96967.35421129348 82613.07290289184 76184.21843730027 112120.81407500466 0.7745896381523525 0.8480435165218586 0.8077863634383554 0.8812719516140863 0.8176857694962173 0.6877047954001756 0.8648470403222895 0.7368219146859455 0.6794832794055157 1.0 16.774694598926175 -6.542131828295731 24.9881864208489 0.7785350369620938 0.8306164077510283 0.017447009160688975 0.09100975655614907 691.0440376921505 896886.2925812437 0.028326921723580877 0.028330609934159354 2.8699093006830187e-07 6.542131828295731 0.05208137078893449 SPPLS(ph)PVGTTPVK ddPTM_PC-9_AZD4547_30min_R2 1 SPPLSPVGTTPVK 13 0 C9J4K0;Q9BVC5-2;Q9BVC5 C9J4K0 C2orf49 Ashwin 1 S(0.118)PPLS(0.828)PVGT(0.042)T(0.013)PVK 116.79 0.00026868 31999000.0 32440.0 25376.0 38231.0 51490.0 39603.0 40193.0 31019.0 36138.0 34057.0 39100.0 True False 42755.24520608276 33578.29574527362 37724.03196030837 39619.77601256991 34104.80704753998 37679.725356170864 33779.63090823464 30553.702468626794 35857.1834912565 37731.12090111375 1.133155978009143 0.8899363428209857 0.9998121195279632 1.0500556322301153 0.9038906407504388 0.9986378473865756 0.8952723932258672 0.8097745770315801 0.9503344357362591 1.0 15.203467339343842 -6.7233652675102675 1.284540352057425 0.903881849942583 1.0055622773796584 0.20242066956458227 0.07866322507449396 0.6658446899460723 2.3094895944926717 0.036788084239138936 0.03436119263029181 1.890752714138125e-07 6.7233652675102675 0.1016804274370754 SPPLS(ph)PVGTTPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPPLSPVGTTPVK 13 0 C9J4K0;Q9BVC5-2;Q9BVC5 C9J4K0 C2orf49 Ashwin 1 S(0.085)PPLS(0.776)PVGT(0.139)T(0.001)PVK 139.77 6.9885e-05 17960000.0 48837.0 51888.0 54086.0 78881.0 113970.0 162360.0 178270.0 166720.0 176730.0 165120.0 True False 57104.13952528232 57039.09772415444 55375.61536229726 74461.55330565236 91638.39664049054 153845.55578155513 161382.97503696824 162343.7766544417 179314.3419096882 195054.94891079934 0.2927592447367056 0.2924257910023037 0.283897515400243 0.3817465474290755 0.4698081087006807 0.7887293126405642 0.8273718556649919 0.8322976554093133 0.9193016783782836 1.0 17.573521077149415 -6.693635924382213 1.216495392828979 0.9068187887355036 0.283261084688543 0.9719205094317445 0.04607262118008901 0.0668200183694299 0.20883619482783367 0.021938817549744846 0.021089752474823892 2.0247158172430936e-07 6.693635924382213 -0.6235577040469606 down SPPLS(ph)PVGTTPVK ddPTM_PC-9_Lapatinib_30min_R1 1 SPPLSPVGTTPVK 13 0 C9J4K0;Q9BVC5-2;Q9BVC5 C9J4K0 C2orf49 Ashwin 1 S(0.009)PPLS(0.99)PVGT(0.001)TPVK 156.2 0.00020195 17007000.0 23380.0 23212.0 30279.0 26429.0 44891.0 70695.0 78920.0 77123.0 85879.0 62840.0 True False 23046.596912633115 23158.254040141022 27789.57750032004 28372.676824559472 42250.59963910172 67671.53964809404 83006.09144147424 80706.41613135372 76206.40267403865 73701.81027096324 0.31270055413703896 0.3142155390077959 0.3770542052922745 0.3849658064062184 0.5732640688711476 0.9181801559459798 1.1262422338922748 1.0950398074977832 1.033982779986914 1.0 16.16941243491955 -6.686007362834867 1.8145350212713196 1.0761423991133765 0.33969346732289957 0.9856618693541299 0.03977665976232183 0.037489538322662434 0.2544192478580335 0.01675887131112476 0.01619818603255468 2.0605949785660236e-07 6.686007362834867 -0.736448931790477 down SPPLSPVGT(ph)TPVK ddPTM_PC-9_Lapatinib_30min_R1 1 SPPLSPVGTTPVK 13 0 C9J4K0;Q9BVC5-2;Q9BVC5 C9J4K0 C2orf49 Ashwin 1 SPPLS(0.331)PVGT(0.569)T(0.101)PVK 122.64 0.00043711 18504000.0 19831.0 20878.0 22600.0 21573.0 46310.0 61906.0 76584.0 66991.0 75141.0 55859.0 True False 19548.20630344001 20829.658273740497 20741.91523852284 23159.550385418344 43586.13684896306 59258.42468993438 80549.14479161006 70103.64642266909 66677.8293101914 65514.1537225611 0.298381421306648 0.3179413468721552 0.31660204795379887 0.35350453405067633 0.6652934422925059 0.9045133199900827 1.2294922580045686 1.0700534531750732 1.0177622013184848 1.0 15.999519000695235 -6.5922651604635085 1.7191026513372496 1.0856670107178394 0.3087223690010533 0.9652598186546422 0.06517190599348013 0.05960934100149731 0.36047463186905976 0.026433339398836415 0.027417028372866244 2.5570242074943885e-07 6.5922651604635085 -0.7769446417167861 down SPPLSPVGTT(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 1 SPPLSPVGTTPVK 13 0 C9J4K0;Q9BVC5-2;Q9BVC5 C9J4K0 C2orf49 Ashwin 1 SPPLSPVGT(0.102)T(0.898)PVK 144.51 0.00022557 8917500.0 26908.0 20285.0 30091.0 37868.0 38357.0 31832.0 26694.0 36807.0 29152.0 35879.0 True False 35464.18427883095 26841.729555204725 29691.97367888989 29138.117654767866 33031.792640014406 29841.540007902662 29069.714286869847 31119.32389071744 30692.915205012465 34622.887130717645 1.024298873312818 0.7752597134336199 0.8575822566959468 0.8415854386942891 0.9540450083005466 0.8619021254708438 0.8396097696046558 0.898807883156231 0.8864920793327347 1.0 15.079438412616167 -9.170934392759795 1.2842751256056562 1.0000766238412935 0.8760341883783006 0.22795999677328715 0.0646037976415449 5.660710556955665 9.907303568699867 0.059809619212266886 0.017622322120775507 6.746299338168979e-10 9.170934392759795 -0.12404243546299287 SPPLSPVGTT(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPPLSPVGTTPVK 13 0 C9J4K0;Q9BVC5-2;Q9BVC5 C9J4K0 C2orf49 Ashwin 1 SPPLS(0.001)PVGT(0.049)T(0.95)PVK 101.72 0.0042458 0.0 15907.0 14503.0 19885.0 24309.0 19582.0 16927.0 15604.0 18529.0 18811.0 9954.4 True False 18599.740922429006 15942.7619930121 20359.133814282457 22947.04554084134 15745.047670563192 16039.31832171953 14125.876156823097 18042.63338309831 19086.07528808435 11759.053921012961 1.5817378717170443 1.3557861117145673 1.7313581476058628 1.9514363736215108 1.3389723166782508 1.3639973444681555 1.201276586680219 1.5343609702186025 1.6230961620116644 1.0 13.521484371835264 SPPLSPVGTT(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 2 SPPLSPVGTTPVK 13 0 C9J4K0;Q9BVC5-2;Q9BVC5 C9J4K0 C2orf49 Ashwin 1 SPPLSPVGT(0.052)T(0.948)PVK;SPPLSPVGT(0.04)T(0.96)PVK 142.39 0.00019889 18518800.0 78044.0 68733.0 75552.0 79933.0 64363.0 57659.0 47050.0 41754.0 64805.0 43723.0 True False 76931.07824848336 68573.85296144287 69340.40619915369 85811.53946867115 60577.294882526694 55193.058979693815 49486.01878258192 43694.043270471084 57505.97847309666 51280.46229276459 1.5002025100568943 1.3372315672575028 1.3521798185687819 1.6733768697084994 1.1812938529431674 1.0762979995108444 0.9650072672914289 0.8520602451089074 1.1214013271719365 1.0 15.646121647443557 -6.569541343194358 2.9576412762907025 0.9886485972983244 1.4487685806972534 0.788468929568871 0.11208999707123479 0.11721473478484334 2.0925761814892563 0.03916159249596584 0.04052437386473999 2.694378825453838e-07 6.569541343194358 0.460119983398929 SPPPS(ph)PPTHR ddPTM_PC-9_AZD4547_30min_R2 1 SPPPSPPTHR 10 0 Q96HA1 Q96HA1 POM121 Nuclear envelope pore membrane protein POM 121 1 S(0.001)PPPS(0.984)PPT(0.015)HR 82.515 0.008392100000000001 2861800.0 1249.9 1481.5 820.98 1682.1 1708.0 842.53 1019.8 4173.8 1168.9 1636.9 True False 1647.342200464947 1960.3659026884786 810.0932687811974 1294.3178331859367 1470.8736822260498 789.8464659103491 1110.5602243856251 3528.8351143824943 1230.6856676433545 1579.5926292335841 1.0428905339120471 1.241057894553259 0.5128494864997271 0.8193997675298964 0.9311727941777719 0.5000317495109998 0.7030674895744906 2.2340159412459903 0.7791158586505188 1.0 10.625336825619982 SPPPS(ph)PPTHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPPPSPPTHR 10 0 Q96HA1 Q96HA1 POM121 Nuclear envelope pore membrane protein POM 121 1 SPPPS(0.996)PPT(0.004)HR 90.861 0.0080143 0.0 1034.1 1782.7 2901.6 2987.0 2111.4 2980.6 3392.3 3230.8 4516.2 1731.8 True False 1209.1527055940055 1959.6746745461405 2970.7851483792797 2819.6480739846616 1697.6863268117195 2824.292088953578 3070.9567858748374 3145.9949233155594 4582.240881189012 2045.7616310787416 0.5910525875668186 0.957919361070817 1.4521658355733107 1.3782876905838952 0.8298553951842962 1.3805577570952452 1.501131284907081 1.5378110897781667 2.2398703796066264 1.0 10.998422338985408 -7.153876757868532 2.0274596553867252 1.6430582043114343 1.0783048414806677 0.30431858358036834 0.3678520741215467 0.4204934251474699 3.3924056132814924 0.17653776466707596 0.12252881981247325 7.016543824905779e-08 7.153876757868532 -0.5647533628307666 SPPPS(ph)PPTHR ddPTM_PC-9_Lapatinib_30min_R1 2 SPPPSPPTHR 10 0 Q96HA1 Q96HA1 POM121 Nuclear envelope pore membrane protein POM 121 1 SPPPS(0.993)PPT(0.007)HR;SPPPS(0.995)PPT(0.005)HR 92.15100000000001 0.0043159999999999995 3023600.0 5120.299999999999 3073.2 5199.8 2428.7 3519.3999999999996 5095.4 5011.3 3096.5 7625.700000000001 3497.4 True False 5047.283583051982 3066.084194216846 4772.292515808452 2607.3146999056958 3312.395811406622 4877.481619957541 5270.760593520784 3240.3746943290125 6766.813363819043 4101.920930007434 1.230468277954552 0.7474752065031368 1.163428695296621 0.6356326083304025 0.8075230770966174 1.1890725597064837 1.284949340432857 0.7899651771988544 1.6496693815613794 1.0 12.002083966878288 -6.77278492057023 24.890469554676315 1.1759928111481013 0.9055622329319711 0.20165746387475358 0.2638043188646225 334.5518292227469 733953.5011715399 0.08791188923922634 0.07821415975203222 1.6873884785549114e-07 6.77278492057023 -0.27043057821613015 SPPREGS(ph)QGELTPANSQSR ddPTM_PC-9_AZD4547_30min_R2 2 SPPREGSQGELTPANSQSR 19 1 J3QQX0;C9JFE4;A0A096LP07;A0A096LPJ3;A8K070;Q13098-5;Q13098;Q13098-7 J3QQX0 GPS1 COP9 signalosome complex subunit 1 1 S(0.008)PPREGS(0.991)QGELT(0.001)PANSQSR;S(0.001)PPREGS(0.999)QGELTPANSQSR 88.765 0.00051749 12272100.0 9971.8 6425.9 10002.3 25435.0 19344.8 9488.7 16578.9 12099.2 9302.0 10241.3 True False 13142.624973674981 8502.946509676607 9869.662966613285 19571.35371683269 16659.108435554146 8895.370088998057 18054.38998241502 10229.546651956643 9793.684729590628 9882.75520420911 1.3298543475080187 0.860382184317908 0.9986752441677146 1.980353991617354 1.6856744998053736 0.9000900968597785 1.8268579570528647 1.0350905633683847 0.9909872831231774 1.0 13.270697590167947 -7.960755012018379 24.999105698026806 1.0013396248847037 1.3583140611718263 0.1731383158523253 0.36080413929616995 286.8599782454177 182729.86152383918 0.20743390229857925 0.09964781476420012 1.094573647355413e-08 7.960755012018379 0.35697443628712255 SPPREGS(ph)QGELTPANSQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPPREGSQGELTPANSQSR 19 1 J3QQX0;C9JFE4;A0A096LP07;A0A096LPJ3;A8K070;Q13098-5;Q13098;Q13098-7 J3QQX0 GPS1 COP9 signalosome complex subunit 1 1 S(0.091)PPREGS(0.9)QGELT(0.009)PANSQSR;S(0.025)PPREGS(0.974)QGELT(0.001)PANSQSR 53.266000000000005 0.018807 16308600.0 18009.6 25762.7 22208.5 23314.4 28119.0 26274.0 26563.0 17856.1 18875.8 17621.300000000003 True False 21058.26957418605 28320.25059624719 22738.03486620526 22008.169754304632 22609.283803930455 24896.145187266444 24046.760340533954 17387.396295101807 19151.822865494785 20815.902199865952 1.0116433759148649 1.3605103600279966 1.0923396280345556 1.0572767657625888 1.0861544019012566 1.196015668608722 1.1552110549735772 0.8352939079053598 0.9200573043438932 1.0 14.345398468465497 -7.752456364482793 24.995349343581015 0.9082566997656578 1.1411442832518661 0.514083956333232 0.09716992126797461 138.2250646502535 384615.7060851235 0.04602986005038796 0.026075265093355466 1.7682498728159892e-08 7.752456364482793 0.2328875834862083 SPPREGS(ph)QGELTPANSQSR ddPTM_PC-9_Lapatinib_30min_R1 2 SPPREGSQGELTPANSQSR 19 1 J3QQX0;C9JFE4;A0A096LP07;A0A096LPJ3;A8K070;Q13098-5;Q13098;Q13098-7 J3QQX0 GPS1 COP9 signalosome complex subunit 1 1 S(0.005)PPREGS(0.995)QGELTPANSQSR;S(0.002)PPREGS(0.998)QGELTPANSQSR 71.428 0.0029820999999999997 10669300.0 11394.5 12027.8 10394.7 8446.9 11645.2 10417.9 9182.0 7915.5 10781.0 9030.7 True False 11232.01234050461 11999.950368085834 9540.08789070236 9068.113204032366 10960.252231344086 9972.350702311034 9657.399032128957 8283.283026953433 9566.730251037034 10591.64446234864 1.06045972185267 1.1329638575712642 0.9007182902159931 0.856157250771384 1.034801750597443 0.9415299708898762 0.9117941096360669 0.7820582588850098 0.9032337032313548 1.0 13.370638979596553 -5.266286759849815 24.943082787526663 0.9113293288350804 1.0967117956381074 0.5269462018868639 0.06825082575281553 276.1999362632428 1421244.0350753183 0.018601911639201624 0.04077465219807215 5.416431313250273e-06 5.266286759849815 0.18538246680302695 SPPS(ph)LHLLEAFK ddPTM_PC-9_AZD4547_30min_R2 1 SPPSLHLLEAFK 12 0 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 1 S(0.384)PPS(0.616)LHLLEAFK 70.488 0.036398 0.0 763.29 1271.9 5615.5 6355.4 5093.4 5204.1 4136.1 6879.8 3778.2 4897.6 True False 1006.0003425817172 1683.0168016398768 5541.034800897478 4890.260719951192 4386.269328483701 4878.686804320377 4504.204887312595 5816.684992076444 3977.9079386518283 4726.136514713418 0.21285892598528094 0.35610837655668753 1.1724237722814643 1.0347269285867688 0.9280877339933703 1.0322780116765646 0.9530416384059357 1.2307484081274267 0.8416828261874783 1.0 12.206445586901394 -5.198200516454965 5.467906551799322 1.0268168200212446 0.26134645529136935 0.8792296584500067 0.10981727326991184 0.06140774727246577 3.6957311793495236 0.02675932620771153 0.07338914221907968 6.335771172326178e-06 5.198200516454965 -0.7654703647298753 down SPPS(ph)PELQGPPSTEK ddPTM_PC-9_AZD4547_30min_R2 1 SPPSPELQGPPSTEK 15 0 A0A087WSV0;Q9HB09;Q9HB09-3;I6LJZ7 A0A087WSV0 BCL2L12 Bcl-2-like protein 12 1 S(0.389)PPS(0.611)PELQGPPSTEK 176.17 5.5491e-05 5808400.0 17461.0 16842.0 20895.0 17833.0 27496.0 23426.0 20322.0 24308.0 18862.0 24552.0 True False 23013.23478863784 22285.847136739372 20617.91864744953 13721.8773671035 23678.655015507895 21961.168516748166 22130.618631069494 20551.757142270737 19859.0068124638 23692.441953047193 0.9713323275939483 0.9406310747074802 0.8702318945556291 0.5791668665601043 0.9994180871027722 0.9269271846384598 0.9340792593235909 0.8674393793176512 0.8382000830399688 1.0 14.53213928272825 SPPS(ph)PGRR ddPTM_PC-9_AZD4547_30min_R2 2 SPPSPGRR 8 1 Q03252 Q03252 LMNB2 Lamin-B2 1 SPPS(1)PGRR;SPPS(1)PGRR 68.626 0.01975 16758700.0 3093.3 2619.7 6993.5 11531.1 7248.200000000001 6640.200000000001 6414.9 6312.1 3335.36 6915.0 True False 4076.9050553630022 3466.466793974354 6900.7616205282775 8872.783048719064 6241.912543039145 6224.98724429741 6985.813672692042 5336.709982628236 3511.6603203276036 6672.90795476219 0.6109637781611355 0.5194836819981121 1.0341460825341489 1.3296726268173549 0.9354111558791306 0.9328747356472801 1.0468919577568194 0.799757769597232 0.5262563704061691 1.0 12.704099888299622 -5.25885861011768 24.926432875486643 0.9592728730390144 0.5652236954066444 0.3901582449885789 0.1924933020020439 223.12495978928777 2155024.758207607 0.05339851437865434 0.12848900017099363 5.50987047783716e-06 5.25885861011768 -0.39404917763237 SPPS(ph)PGRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPPSPGRR 8 1 Q03252 Q03252 LMNB2 Lamin-B2 1 SPPS(1)PGRR;SPPS(1)PGRR 64.374 0.025069 11232700.0 5736.2 5454.4 7332.5 6156.3 6356.0 4607.799999999999 5657.0 5502.7 6411.9 3441.5 True False 6707.225364885732 5995.8767851261955 7507.334608661101 5811.382469993897 5110.587426927772 4366.15885643169 5121.1280068667165 5358.259955592587 6505.661907376959 4065.4167071009906 1.6498248145559942 1.4748492509152396 1.8466334817653929 1.4294678476239002 1.2570882138603898 1.0739757252449418 1.2596809566708707 1.3180100200388831 1.6002447906542117 1.0 11.989187521453502 -5.994761193851376 5.110772978986412 1.2642217629295827 1.6414746850023385 0.5284508664206018 0.17109248373746186 0.1485706820348035 11.668938775339017 0.05011886399490023 0.07177400267284924 1.012135845907392e-06 5.994761193851376 0.37725292207275585 SPPS(ph)PGRR ddPTM_PC-9_Lapatinib_30min_R1 1 SPPSPGRR 8 1 Q03252 Q03252 LMNB2 Lamin-B2 1 SPPS(1)PGRR 69.27600000000001 0.018937 5675000.0 1942.6 4618.7 3803.7 3376.0 3650.6 3478.9 3409.6 1082.3 3302.8 3484.1 True False 1914.898167770789 4608.005683922079 3490.9744687066072 3624.282302005858 3435.8788853557467 3330.115556711993 3586.1324046990726 1132.587609130403 2930.8038839741325 4086.3220427285687 0.4686116629447419 1.127665816775705 0.8543072308553467 0.8869301695041657 0.8408243034759688 0.8149420241211257 0.8775941707972915 0.27716552863125243 0.7172229338089908 1.0 11.99658719189991 SPPS(ph)PVER ddPTM_PC-9_Lapatinib_30min_R1 1 SPPSPVER 8 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 S(0.05)PPS(0.95)PVER 79.07 0.021233000000000002 84568000.0 33295.0 29711.0 29457.0 25374.0 29703.0 27011.0 10271.0 12620.0 26558.0 11665.0 True False 32820.207194444796 29642.206004938413 27035.15916730829 27240.088605182642 27955.92793834487 25855.80249571637 10802.78212361103 13206.371271575055 23566.758371861764 13681.27970736453 2.3989135443797647 2.1666252455157564 1.9760694719774983 1.991048292837658 2.043370834915129 1.8898672528271157 0.7896031917099081 0.9652877182582682 1.7225551173532367 1.0 13.739915561609555 -7.122793739932206 4.804696534000293 1.1210294736370683 2.0919538870776178 0.7763826807185954 0.2537710209916602 0.1110739480401058 3.8761139570258716 0.10137152105788465 0.07810586984722599 7.537134408910084e-08 7.122793739932206 0.9709244134405495 SPPS(ph)SSEIFTPAHEENVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPPSSSEIFTPAHEENVR 18 0 I3L3A7;I3L2L5;I3L317;I3L4Q0;C9JLW8 I3L3A7 FAM195B Protein FAM195B 1 S(0.134)PPS(0.7)S(0.134)S(0.031)EIFTPAHEENVR 80.975 0.0018891 4921700.0 3861.7 7216.8 11445.0 6252.8 4345.0 5118.1 5365.1 5302.5 2955.7 2462.8 True False 4515.409537948331 7933.236209830361 11717.892205404201 5902.475887851115 3493.6284408434794 4849.697826099886 4856.878888039708 5163.314993463152 2998.9215208649653 2909.286144485928 1.5520678660318594 2.7268669411795403 4.027755134232338 2.0288399266047734 1.2008541846133203 1.6669717536350586 1.6694400780222738 1.7747704203140566 1.030810092898193 1.0 11.506449485166524 -5.994165766278588 24.977784029638947 1.4713370087894417 2.80862783245066 0.5035962272298078 0.6108086674910258 129.43968313227114 554154.3931385705 0.17451067026681236 0.25801042119396905 1.0135244587724374e-06 5.994165766278588 1.3372908236612182 SPPS(ph)TGSTYGSSQKEESAASGGAAYTK ddPTM_PC-9_AZD4547_30min_R2 1 SPPSTGSTYGSSQKEESAASGGAAYTK 27 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.288)PPS(0.298)T(0.105)GS(0.105)T(0.105)Y(0.035)GS(0.039)S(0.02)QKEES(0.003)AAS(0.001)GGAAYTK 42.472 0.028979 33082000.0 8040.8 11224.0 9592.8 6511.6 7087.9 11033.0 10032.0 11915.0 10138.0 11517.0 True False 10597.607140970116 14851.938502717168 9465.59320417582 5010.451223217137 6103.867431059733 10343.10476587051 10924.828565440865 10073.810529461742 10673.873982862797 11113.79333550197 0.9535544544558926 1.336351869642388 0.8516977883634808 0.4508317792100489 0.5492154880693616 0.9306547686855425 0.9829972751555964 0.9064241366880468 0.9604168136513846 1.0 13.44006369782987 -5.38474048825785 7.15992987356797 0.808940704510667 1.1424122411370865 0.29170243530620144 0.1958099427772476 0.3043859655937575 16.308604138081083 0.05587970308097974 0.11716714430030405 4.123438406787974e-06 5.38474048825785 0.3334715366264195 SPPS(ph)TGSTYGSSQKEESAASGGAAYTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPPSTGSTYGSSQKEESAASGGAAYTK 27 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.101)PPS(0.365)T(0.365)GS(0.03)T(0.033)Y(0.03)GS(0.033)S(0.033)QKEES(0.011)AAS(0.001)GGAAYTK 41.908 0.032077 30854000.0 4856.3 6785.7 6500.2 5393.0 6206.3 3828.8 4744.0 4756.3 3889.1 4109.9 True False 5678.375673702901 7459.3394508710135 6655.189420145776 5090.847694341906 4990.220067297331 3628.0109877828163 4294.6139764143 4631.4521647164165 3945.970730045653 4854.992336049499 1.1695951879346091 1.5364266170893008 1.3707929816344666 1.048579965109548 1.0278533356775321 0.7472742976016569 0.8845768806936618 0.9539566376504363 0.812765594035208 1.0 12.245253302911681 -5.95795776730975 2.0262616617033253 0.8885053631499902 1.3842790181728197 0.7569984189069551 0.11466384449335537 0.1445919593415523 1.1994584200433782 0.03561592994244173 0.05849010600437867 1.1016464332384008e-06 5.95795776730975 0.49577365502282955 SPPSLHLLEAFK ddPTM_PC-9_AZD4547_30min_R2 1 SPPSLHLLEAFK 12 0 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 0 96.64 0.0035421 982230.0 5832.9 5371.0 16045.0 21475.0 17884.0 20704.0 12094.0 23214.0 16666.0 16028.0 False True 7687.640868143045 7107.070714370449 15832.232816383243 16524.270535442585 15401.115300310692 19409.37560705004 13170.342570817567 19626.809704651678 17546.930735686652 15466.864598543518 0.4970393850132349 0.4595030019878565 1.0236226428124373 1.0683658882614542 0.9957490221877925 1.2549004669555186 0.8515198724929545 1.2689585261191136 1.1344853136775381 1.0 13.916893146692564 -5.289802533679359 4.715238973482544 1.083545216062619 0.4713138902206026 0.8060145063268617 0.11718653285530978 0.06943651635261633 4.0494520822350895 0.029726108379834325 0.069691803671874 5.130946263688952e-06 5.289802533679359 -0.6122313258420164 down SPPSLHLLEAFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPPSLHLLEAFK 12 0 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 0 83.226 0.016031999999999998 0.0 2967.5 4057.3 7566.6 8518.0 12438.0 9694.0 7184.6 6320.6 8892.0 4671.0 False True 3469.839139203377 4460.081930238435 7747.016440490296 8040.764075728599 10000.863186930083 9185.629574688313 6504.022676000458 6154.690947229272 9022.028677988726 5517.815324384347 0.6288429269949382 0.8083057637917722 1.4040006750959309 1.4572368959495308 1.8124679060450313 1.6647221834509665 1.1787314894824152 1.115421699604632 1.635072605296982 1.0 12.429881456638991 -5.204813299574335 3.2915169766235564 1.4342222987213273 0.6603369039816498 0.5641775018845937 0.24397090086906725 0.1817866481049818 3.8947707815300436 0.06762934846886157 0.21107943193930942 6.240030327509054e-06 5.204813299574335 -0.7738853947396775 SPPSLHLLEAFK ddPTM_PC-9_Lapatinib_30min_R1 1 SPPSLHLLEAFK 12 0 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 0 75.73899999999999 0.024225999999999998 0.0 5631.7 4068.2 7992.1 6195.6 9906.6 9289.3 7373.4 5470.0 8814.8 6672.7 False True 5551.390925272704 4058.7803328494633 7335.020388398151 6651.245091915722 9323.913265124978 8892.018293415942 7755.158573676716 5724.156169216764 7821.984400040934 7826.067304186137 0.7093461772687905 0.5186232337509332 0.9372549587549129 0.8498834514696791 1.1913919089524887 1.13620519065299 0.9909394172381455 0.7314217916519747 0.9994782942713744 1.0 12.934071802132847 -5.3484976908006745 5.010071787489487 0.9824572409923761 0.6153930323283165 0.5608923844312024 0.12961017919652976 0.1594131157352396 6.678889671568263 0.03709305204783163 0.08072976579980946 4.482314332941634e-06 5.3484976908006745 -0.36706420866405953 SPPST(ph)GSTYGSSQK ddPTM_PC-9_Lapatinib_30min_R1 1 SPPSTGSTYGSSQK 14 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.335)PPS(0.177)T(0.366)GS(0.114)T(0.008)YGSSQK 111.81 0.0016742 0.0 972.79 3880.2 3349.9 2231.4 5072.4 3754.3 5745.8 5189.6 3552.4 3824.4 True False 958.9178362121628 3871.215635298776 3074.484152987947 2395.504599732187 4774.051404722096 3593.7373407007503 6043.289409584679 5430.72776156624 3152.291303569612 4485.442444307321 0.21378444782613787 0.8630621579398285 0.6854360949140957 0.534062052846633 1.0643434764793518 0.8012001904654301 1.347311772388138 1.2107451670589648 0.7027826892685533 1.0 12.13103458434964 -6.264760844426688 24.8811134000995 1.0369203653721424 0.6026808854525267 0.47414773705759783 0.22945170616869634 253.5229000165012 1899138.677470685 0.0700074998104683 0.0827125439195946 5.435495688273513e-07 6.264760844426688 -0.43423947991961565 SPPSTGS(ph)TYGSSQKEESAASGGAAYTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPPSTGSTYGSSQKEESAASGGAAYTK 27 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.156)PPS(0.047)T(0.221)GS(0.316)T(0.067)Y(0.059)GS(0.067)S(0.067)QKEESAASGGAAYTK 70.449 9.3647e-05 51646000.0 34193.0 59390.0 48797.0 34584.0 44689.0 30897.0 41340.0 27577.0 27639.0 28378.0 True False 39981.199557466214 65285.846705163654 49960.50554365306 32646.37060284082 35932.511252670716 29276.70692894008 37423.97592431852 26853.13297024676 28043.16808714917 33522.70675987562 1.1926602420220127 1.9475111951075006 1.4903481959712264 0.9738584308447398 1.071885737331911 0.8733395885556082 1.1163769140835742 0.8010431008031881 0.8365424751653682 1.0 15.032851022363301 -5.726663977332485 4.273103305451471 0.9500423958846724 1.6021278726532353 0.6615532467595133 0.19357444055582143 0.11010028287778519 4.407056746832759 0.05162115570115646 0.08887237422413484 1.8764457916620544e-06 5.726663977332485 0.6520854767685629 SPPVLGSAAAS(ph)PVHLK ddPTM_PC-9_AZD4547_30min_R2 1 SPPVLGSAAASPVHLK 16 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 SPPVLGSAAAS(1)PVHLK 91.64 0.0018244 9923400.0 48065.0 40322.0 58630.0 69379.0 70059.0 62377.0 53666.0 74046.0 54502.0 65963.0 True False 63348.670185892996 53355.29796031379 57852.5278918385 53384.74344486473 60332.517156366965 58476.55632925813 58442.17003518237 62603.89210780727 57382.864451961774 63653.65544757461 0.9952086763982816 0.8382126302904538 0.908864188318078 0.8386752193490695 0.9478248614654512 0.9186676855882949 0.9181274763287641 0.9835082002378963 0.90148576776117 1.0 15.957955745909524 -8.38962707082374 0.4217408452241781 0.9996616196899691 0.8948665637181804 0.21982305163099047 0.04868690332835003 1.6241578703434278 0.7860826288491908 0.06347887516213545 0.03605709101415453 4.077302459595642e-09 8.38962707082374 -0.10479505597178873 SPQDPGDPVQY(ph)NRTTDEELSELEDR ddPTM_PC-9_Lapatinib_30min_R1 1 SPQDPGDPVQYNRTTDEELSELEDR 25 1 Q9BV36;Q9BV36-4;H7C052;H7C3K9;Q9BV36-5;Q9BV36-2;H7C2D8 Q9BV36;Q9BV36-2 MLPH Melanophilin 1 SPQDPGDPVQY(0.646)NRT(0.176)T(0.176)DEELS(0.001)ELEDR 77.543 0.00059671 3034300.0 16954.0 8141.7 15698.0 9796.1 9684.1 10812.0 7502.8 8367.2 13271.0 7586.6 True False 16712.232851017183 8122.848393874561 14407.371036032362 10516.537872831625 9114.50027767314 10349.595964003003 7891.25827251765 8755.970657965361 11776.28023017462 8897.933701490936 1.8782150341507808 0.912891539359694 1.6191816571546567 1.1819078704833994 1.024338973906483 1.1631459967238043 0.88686413466931 0.9840453920777373 1.3234848252691958 1.0 13.119254633694265 -4.751082025239649 24.990320787023524 1.1295957905561367 1.8782165911165614 0.5412179892643436 0.2088272056012965 351.0706108810347 847009.5487303535 0.052522911917661924 0.7194378369706569 1.773854421198395e-05 4.751082025239649 0.7486208005604247 SPQEEDFRCPS(ph)DEDFR ddPTM_PC-9_AZD4547_30min_R2 2 SPQEEDFRCPSDEDFR 16 1 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 1 SPQEEDFRCPS(1)DEDFR;SPQEEDFRCPS(1)DEDFR 95.554 0.0011544 24376000.0 28371.0 41106.0 34850.0 24502.0 31926.0 48720.0 38317.0 53630.0 44286.0 34045.0 True False 37392.38784654053 54392.71062835815 34387.866229414525 18853.442452126383 27493.62598287403 45673.53069819732 41727.13877013532 45342.71579479924 46626.86754833911 32853.09491249149 1.138169415884258 1.6556342948279374 1.046716186740126 0.573871122411602 0.8368656303494966 1.3902352524124357 1.2701128731183777 1.3801657321958702 1.4192534271896107 1.0 15.003741665000689 -6.783538291168421 24.979344801629704 1.3143488214896004 1.0572216680065687 0.15710674581189754 0.277274753472754 491.44212243962124 555494.0637158309 0.10889591890602049 0.09611289353834215 1.6461208236402673e-07 6.783538291168421 -0.2571271534830317 SPQEEDFRCPS(ph)DEDFR ddPTM_PC-9_Lapatinib_30min_R1 2 SPQEEDFRCPSDEDFR 16 1 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 1 S(0.066)PQEEDFRCPS(0.934)DEDFR;SPQEEDFRCPS(1)DEDFR 60.09 0.022119999999999997 37254000.0 14328.1 27484.0 30585.0 25267.0 34473.0 30610.0 32400.0 30793.0 28753.0 29189.0 True False 14123.77866654827 27420.362486611917 28070.419361514207 27125.21946824111 32445.365916525683 29300.881655395122 34077.51346558245 32223.755195373273 25514.534357487046 34234.27975810229 0.4125624598018765 0.8009621549032966 0.8199506331039644 0.7923408834626157 0.9477449546414594 0.8558930365246089 0.9954207801762578 0.9412715974474917 0.7452919862129851 1.0 15.063154039990467 -4.540553611071434 1.47194568580197 0.8931652365724122 4.312593774713458e-26 0.753959526602719 0.08104481272121378 1.0476249895540866 1.3471142610842057 0.022747807965176982 1.6235405375509258 2.8803574648259182e-05 4.540553611071434 -0.8931652365724122 down SPQELT(ph)PSSQSEGVMLK ddPTM_PC-9_AZD4547_30min_R2 1 SPQELTPSSQSEGVMLK 17 0 Q99990;H0Y5G3 Q99990 VGLL1 Transcription cofactor vestigial-like protein 1 1 S(0.004)PQELT(0.809)PS(0.141)S(0.044)QS(0.001)EGVMLK 99.81299999999999 0.004663800000000001 9028100.0 35733.0 21681.0 41418.0 54720.0 45444.0 36596.0 32599.0 46420.0 43251.0 40946.0 True False 47095.35070742775 28688.959254936814 40868.77025795954 42105.14941557247 39134.885020539 34307.64633479534 35500.24784736909 39246.85562548167 45537.15956133347 39512.49300299245 1.191910383985668 0.7260731245878127 1.0343252766881699 1.0656161182333816 0.990443326812488 0.8682733922204573 0.8984562893736041 0.9932771294008034 1.1524749794421918 1.0 15.270021254201868 -8.017852522896742 22.440821777379945 1.0751171392084673 0.9607770874853134 0.10677711497319964 0.12241602483810177 405.3307379726338 509495.7258611025 0.07613040924100808 0.030238241341904788 9.597264787418108e-09 8.017852522896742 -0.11434005172315387 SPQELT(ph)PSSQSEGVMLK ddPTM_PC-9_Lapatinib_30min_R1 1 SPQELTPSSQSEGVMLK 17 0 Q99990;H0Y5G3 Q99990 VGLL1 Transcription cofactor vestigial-like protein 1 1 SPQELT(0.862)PS(0.079)S(0.057)QS(0.002)EGVMLK 105.02 0.0028644 5542100.0 33688.0 37560.0 35789.0 29294.0 29786.0 29233.0 30773.0 30502.0 31649.0 27630.0 True False 33207.60294237741 37473.032127679544 32846.566569535105 31448.378481919317 28034.046041529135 27982.772735451363 32366.275366554597 31919.234273025555 28084.356341255083 32405.808685339212 1.024742300518516 1.1563677515825366 1.013601199972377 0.9704549819226376 0.8650932403428057 0.8635110145580509 0.9987800545523031 0.9849849631268794 0.8666457490369864 1.0 14.983964816437847 -5.646341041696259 2.623892770309926 0.9297413130396407 1.0901689563877612 0.5206949396130285 0.059722665760346065 0.20717606815972262 2.8701501583738427 0.017381654390537973 0.034622886244523435 2.2576621825598242e-06 5.646341041696259 0.16042764334812054 SPQELTPS(ph)SQSEGVMLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPQELTPSSQSEGVMLK 17 0 Q99990;H0Y5G3 Q99990 VGLL1 Transcription cofactor vestigial-like protein 1 1 S(0.002)PQELT(0.142)PS(0.41)S(0.41)QS(0.037)EGVMLK;S(0.001)PQELT(0.142)PS(0.646)S(0.186)QS(0.025)EGVMLK 80.545 0.0049977 10941700.0 53406.0 55967.0 50010.0 59611.0 57218.0 51781.0 62369.0 63622.0 49013.0 36249.0 True False 62446.5809834189 61523.033886982565 51202.42806398116 56271.188931469565 46006.54364284976 49065.513204759234 56460.956807542876 61951.98991308112 49729.722401513856 42820.6567530739 1.458328426476928 1.4367606326487767 1.195741306800615 1.3141131686970242 1.0744007012350918 1.1458374748359517 1.3185448586911224 1.4467781349157816 1.1613488949569646 1.0 15.386019302482978 -5.254305858206108 21.43461753723648 1.2239274190008154 1.4475448436938085 0.37516597799177165 0.12259333467413328 87.51207711923448 262937.7755774101 0.03199398468381934 0.08019144715915952 5.567934809098892e-06 5.254305858206108 0.22361742469299317 SPQELTPS(ph)SQSEGVMLK ddPTM_PC-9_Lapatinib_30min_R1 1 SPQELTPSSQSEGVMLK 17 0 Q99990;H0Y5G3 Q99990 VGLL1 Transcription cofactor vestigial-like protein 1 1 S(0.001)PQELT(0.044)PS(0.319)S(0.319)QS(0.319)EGVMLK 64.55 0.019977 6560300.0 30410.0 34486.0 38206.0 26772.0 28357.0 32682.0 31700.0 26165.0 30605.0 31053.0 True False 29976.34782348899 34406.14978581351 35064.850159424925 28740.902188773936 26689.09701200705 31284.267045463046 33341.27089070877 27380.72142002864 27157.942615062475 36420.46967447842 0.8230631864831458 0.9446926438162756 0.9627786372012812 0.78914144835738 0.7328048553615821 0.8589748381906628 0.9154541714785355 0.7517948468197715 0.7456779898171756 1.0 15.152461906824984 -5.768821264199279 24.987096473681007 0.8183572108210024 0.9136296082569618 0.15648015491248934 0.08575554211989454 262.1597591295866 887393.0614351069 0.023987777937535957 0.036404669833670786 1.7028591833751497e-06 5.768821264199279 0.09527239743595939 SPQIS(ph)MSDIDLNLK ddPTM_PC-9_AZD4547_30min_R2 1 SPQISMSDIDLNLK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(0.276)PQIS(0.644)MS(0.08)DIDLNLK 64.374 0.036443 2734100.0 4995.9 10720.0 9527.6 9565.5 7938.7 10042.0 10799.0 18445.0 17940.0 12223.0 True False 6584.492278824563 14185.030358974354 9401.25779877675 7360.321760501796 6836.548536936735 9414.072152530742 11760.090079564972 15594.749073933845 18888.27177476412 11795.076490391655 0.55824074427905 1.2026230071953812 0.7970493287122873 0.6240164501262507 0.5796103605182918 0.7981357441979715 0.9970338122982769 1.322140563194942 1.6013691636633836 1.0 13.525897153951403 -7.589126521406529 2.6198628705832445 1.3530136867119396 0.7691180757901478 0.5549623886762702 0.21869123921800102 0.2088598806262318 2.886676107338464 0.12443019058374603 0.06445269055213328 2.5755707161972775e-08 7.589126521406529 -0.5838956109217918 SPQIS(ph)MSDIDLNLKGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPQISMSDIDLNLKGPK 17 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(0.108)PQIS(0.779)MS(0.114)DIDLNLKGPK 76.85 0.012272 8391700.0 49499.0 28136.0 33339.0 44107.0 69790.0 58638.0 47107.0 92866.0 61700.0 47815.0 True False 57878.203050186305 30929.156135653895 34133.9281988616 41635.82778682334 56115.15049170686 55562.920053700625 42644.68393485424 90428.36589966038 62602.24577506799 56483.480996668244 1.0246925654883121 0.5475787892300458 0.6043170073189192 0.7371328227677626 0.9934789694533326 0.9837021209259054 0.7549939058708102 1.6009701297445604 1.108328393902647 1.0 15.785541382143627 -6.995074729569913 0.9681187186192172 1.2133898680682962 0.7134082589660592 0.36271387665597865 0.22896350593890857 0.543720927102909 1.0554445406438528 0.15069212243158517 0.10926484033846025 1.0114054055505089e-07 6.995074729569913 -0.499981609102237 SPQIS(ph)MSDIDLNLKGPK ddPTM_PC-9_Lapatinib_30min_R1 1 SPQISMSDIDLNLKGPK 17 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(0.394)PQIS(0.594)MS(0.013)DIDLNLKGPK 60.246 0.01706 5013100.0 28881.0 16856.0 21437.0 16144.0 22721.0 19437.0 15553.0 15848.0 19566.0 22300.0 True False 28469.15164387327 16816.970967629542 19674.532609212998 17331.283614805267 21384.595451204714 18605.724819860017 16358.258238586535 16584.35593596842 17362.27104088587 26154.525287117795 1.0884981215046379 0.6429851348100212 0.7522420075773095 0.6626495195208782 0.8176250655077852 0.711376888535007 0.62544657412091 0.6340912616042361 0.663834302105935 1.0 14.674772964433023 -4.755172690023691 24.999768801224242 0.710443229909177 1.088498746276225 0.4986327063434811 0.10915145313469403 161.6366786712075 644757.6993079548 0.025370849077310832 0.23074961481140732 1.7572247436409175e-05 4.755172690023691 0.37805551636704804 SPQLS(ph)LSPRPASPK ddPTM_PC-9_Lapatinib_30min_R1 1 SPQLSLSPRPASPK 14 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 S(0.016)PQLS(0.782)LS(0.179)PRPAS(0.023)PK 59.606 0.027816000000000004 13045000.0 57181.0 33848.0 36339.0 31250.0 35307.0 38654.0 26599.0 23715.0 27093.0 25476.0 True False 56365.58845428885 33769.62703561492 33351.3476925965 33548.22924694402 33230.31167623278 37000.858526874996 27976.166070093463 24816.88547586391 24041.501038061993 29879.4926553638 1.8864305731165223 1.130194124281852 1.1161952472646637 1.122784433922496 1.1121444416582975 1.2383362379559282 0.9362999028389238 0.8305658252670807 0.8046154369273133 1.0 14.866868031364527 -2.453385757532863 1.139766940089132 1.009433831401766 199.9999999885718 0.7978713364107343 0.1297541812432474 172.1668201290582 1.3069004356772045 0.044112899809873554 88349.42089640509 0.0035205802026421922 2.453385757532863 198.99056615717004 SPQNDDHS(ph)DTDSEENRDNQQFLTTVK ddPTM_PC-9_Lapatinib_30min_R1 2 SPQNDDHSDTDSEENRDNQQFLTTVK 26 1 Q86W56;Q86W56-3;Q86W56-2 Q86W56 PARG Poly(ADP-ribose) glycohydrolase 1 S(0.026)PQNDDHS(0.968)DT(0.005)DS(0.001)EENRDNQQFLTTVK;S(0.001)PQNDDHS(0.464)DT(0.464)DS(0.071)EENRDNQQFLTTVK 63.63 0.00036586 14460800.0 40389.0 47882.0 59200.0 47515.0 54189.0 53815.0 51558.0 52689.0 64190.0 48963.0 True False 39813.045453564526 47771.13217086131 54332.80451860848 51009.411605393434 51001.70955967306 51513.45789889213 54227.4209647685 55137.12329065117 56960.24624933378 57426.18931090353 0.6932907429747426 0.8318701405073206 0.9461328562905756 0.8882604299099516 0.8881263091226801 0.8970377194976309 0.9442977431635415 0.9601389880171323 0.9918862270479563 1.0 15.809421210041199 -3.974027263729122 0.8326853687238769 0.9427017839126934 3.272444790916702e-32 0.8113774664711996 0.03726946920400329 3.6297335377372497 0.7300386149596804 0.014222432730763028 4.327933668924249 0.00010616289091690091 3.974027263729122 -0.9427017839126934 SPQPDPVKT(ph)PTSSK ddPTM_PC-9_AZD4547_30min_R2 1 SPQPDPVKTPTSSK 14 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 SPQPDPVKT(0.45)PT(0.234)S(0.234)S(0.081)K 61.52 0.037291000000000005 3853600.0 15949.0 32269.0 32487.0 44586.0 43407.0 32826.0 23593.0 28030.0 27947.0 44076.0 True False 21020.450240191574 42699.32319531189 32056.201153371272 34307.386546833215 37380.68730935956 30773.38503076818 25692.73129430285 23698.607565322072 29424.221365068715 42532.91265569028 0.4942161006078982 1.0039125121989347 0.7536798952112823 0.806607974971199 0.8788649771521954 0.7235193432409137 0.6040670551365482 0.5571828046944617 0.6917988806283218 1.0 15.376292033714579 -6.991624649300826 22.387458758198942 0.6745653743420583 0.7989215328302286 0.023469288727274495 0.16380381971456343 117.3547918155583 313684.40178602136 0.05456962570055185 0.04800434187726197 1.0194721136269414e-07 6.991624649300826 0.12435615848817028 SPQPLGGSHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPQPLGGSHR 10 0 H3BQD8;O43561-2;O43561;O43561-3 H3BQD8 LAT Linker for activation of T-cells family member 1 0 70.399 0.034306 0.0 13042.0 13456.0 16820.0 17391.0 25771.0 17301.0 13267.0 22284.0 20202.0 11573.0 False True 15249.753008758365 14791.822752394044 17221.05259020523 16416.638652382735 20721.357548671425 16393.705103330158 12010.253715237886 21699.068611849685 20497.416031570872 13671.093288182414 1.115474284850399 1.0819780423252918 1.259669013091402 1.2008285150518012 1.5157059579560774 1.1991509938346503 0.8785145022468545 1.587222627659693 1.499325298971464 1.0 13.738841000574558 -5.345352029883624 2.7999485940347113 1.282874732966953 1.0940142790188812 0.08748504278468072 0.21269857528255817 0.6800305587783245 10.2208366245452 0.0601381952687413 0.16203312507117196 4.514898279459309e-06 5.345352029883624 -0.18886045394807183 SPQPVCS(ph)PAGSEGTPK ddPTM_PC-9_AZD4547_30min_R2 1 SPQPVCSPAGSEGTPK 16 0 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 S(0.096)PQPVCS(0.632)PAGS(0.27)EGT(0.003)PK 139.38 1.8221e-05 17198000.0 38008.0 30271.0 39777.0 49538.0 46030.0 47032.0 30224.0 41657.0 31493.0 41041.0 True False 50093.753384488125 40055.50876833138 39249.530990169886 38117.77945447053 39639.52903563526 44091.08160504139 32913.87744835371 35219.86783263008 33157.655685766214 39604.167081908156 1.2648606718804545 1.0113963181068744 0.9910454854155922 0.9624689082751439 1.0008928846718068 1.113294000448325 0.8310710683621301 0.8892970216944445 0.8372264367330473 1.0 15.273364615715842 -1.5228787453388144 0.8824563621302011 0.9421593290045316 139.11864051309766 0.5775924928158691 0.07984457934315566 637.1177541586164 1.5280770153822036 0.02897978441490743 177106.83345438182 0.029999999995960563 1.5228787453388144 138.17648118409312 SPQPVCS(ph)PAGSEGTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPQPVCSPAGSEGTPK 16 0 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 S(0.002)PQPVCS(0.722)PAGS(0.261)EGT(0.015)PK;SPQPVCS(0.974)PAGS(0.025)EGT(0.001)PK;S(0.001)PQPVCS(0.993)PAGS(0.006)EGTPK 180.03 4.656499999999999e-06 29396600.0 54436.0 53970.0 47549.0 66108.0 66442.0 58763.0 63639.0 60626.0 51400.0 48864.0 True False 63650.93963999154 59327.7849246958 48682.74849058668 62404.183085027755 53423.16705788782 55681.36483365069 57610.65321353912 59034.63173855672 52151.62776075354 57722.65639278883 1.1027028833680517 1.0278075998613865 0.8433906464614562 1.081103798487413 0.9255147007503602 0.9646362158863993 0.9980596322787442 1.0227289495625465 0.9034862741914409 1.0 15.81685007363565 -5.001138256184193 14.386442348300777 0.9693337338256524 1.0840133100454896 0.30958887223551923 0.06292711777559105 0.2186746396076928 2844.404528920931 0.014787068889805091 0.05116694259703545 9.973824999211252e-06 5.001138256184193 0.11467957621983726 SPQPVCS(ph)PAGSEGTPK ddPTM_PC-9_Lapatinib_30min_R1 2 SPQPVCSPAGSEGTPK 16 0 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 S(0.315)PQPVCS(0.671)PAGS(0.014)EGTPK;S(0.001)PQPVCS(0.979)PAGS(0.02)EGTPK 147.6 1.0064e-05 36128000.0 61017.0 64238.0 67738.0 61471.0 63018.0 71663.0 57858.0 60596.0 69722.0 43754.0 True False 60146.88639085265 64089.26085777098 62168.84311624154 65991.78240124459 59311.40513815495 68598.14054461216 60853.60413863175 63411.51137657389 61869.174154791246 51316.820601459694 1.1720696193937974 1.2488938345480425 1.2114710612931692 1.2859678683867541 1.1557887734079115 1.3367574167808227 1.18584127826697 1.2356866741422825 1.2056314757939504 1.0 15.647144168749495 -9.22112855384045 1.2991963342199047 0.999765063821972 1.2315745677475896 0.6406767884837072 0.05111415548518415 2.872850426228771 4.802124744639204 0.04591029024990606 0.013399210581328267 6.009958126904735e-10 9.22112855384045 0.2318095039256175 SPQPVCSPAGS(ph)EGTPK ddPTM_PC-9_AZD4547_30min_R2 1 SPQPVCSPAGSEGTPK 16 0 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 S(0.001)PQPVCS(0.347)PAGS(0.65)EGT(0.003)PK 195.45 8.314e-12 20975000.0 36305.0 29353.0 34884.0 45972.0 48576.0 37024.0 33840.0 38344.0 31223.0 43106.0 True False 47849.234809088615 38840.78322079981 34421.41536719933 35373.86566031974 41832.06088279426 34708.88342713583 36851.69444323351 32418.815857463753 32873.38403698215 41596.872060445254 1.1503084832810968 0.9337428825023064 0.8275000898428343 0.8503972512384407 1.0056540025896 0.8344108993748292 0.8859246529326428 0.7793570586354502 0.790285000016664 1.0 15.344187426364186 -4.787408172233763 3.0272453531373733 0.8672404256870709 1.1938957516461712 0.5632037230810082 0.07342687144632187 0.26828637145987044 3.6195841013534746 0.018844869942360697 0.21322580502358027 1.6315178429249717e-05 4.787408172233763 0.3266553259591003 SPQQTVPYVVPLS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPQQTVPYVVPLSPK 15 0 Q9UQR0;H0Y6S1;B4DRC2 Q9UQR0 SCML2 Sex comb on midleg-like protein 2 1 SPQQTVPYVVPLS(1)PK;SPQQT(0.016)VPY(0.012)VVPLS(0.972)PK 156.73 2.8907e-14 0.0 23897.0 28987.0 22026.9 33313.0 29133.0 25208.0 30061.0 29312.0 28197.0 21585.0 True False 27942.290112735645 31864.63779159085 22552.104833483427 31446.58061220319 23424.597782990375 23886.048103852187 27213.404457207063 28542.591058631195 28609.32778151688 25498.189633234007 1.0958538827523672 1.2496823598040425 0.8844590599518214 1.2332867966130476 0.9186768990241981 0.9367742748575147 1.0672681021140995 1.1193967677387242 1.1220140799418896 1.0 14.638107199187614 -5.237750401508714 24.996453431596645 1.0400367924114706 1.1727681041347433 0.20857786880803397 0.10683434049434987 1266.2585919437947 1336143.2032638248 0.026654835714658282 0.07043468622549207 5.784283872789091e-06 5.237750401508714 0.13273131172327268 SPQS(ph)PGGNICHLGAPK ddPTM_PC-9_AZD4547_30min_R2 1 SPQSPGGNICHLGAPK 16 0 Q9H609 Q9H609 ZNF576 Zinc finger protein 576 1 S(0.001)PQS(0.999)PGGNICHLGAPK 105.92 0.00061058 6808700.0 35203.0 33952.0 55366.0 71055.0 56774.0 47978.0 47145.0 60511.0 47997.0 53610.0 True False 46396.82173211256 44926.320032453106 54631.81066449824 54674.36753880664 48891.91009057477 44977.928075494885 51340.81366803323 51160.415354448945 50534.02343218247 51733.13021761401 0.8968493021192724 0.8684245442615159 1.0560314141961062 1.0568540374189692 0.9450792922236152 0.8694221263298093 0.9924165317673509 0.9889294372724798 0.9768212984525094 1.0 15.658800866911774 -5.237563407531606 24.8969087797195 0.982477283088058 0.8826368961923453 0.3940361010919067 0.0509957182006412 858.3949276023889 895096.568012762 0.014325004847032143 0.037856748648920455 5.786774945511077e-06 5.237563407531606 -0.09984038689571273 SPQS(ph)PGGNICHLGAPK ddPTM_PC-9_Lapatinib_30min_R1 2 SPQSPGGNICHLGAPK 16 0 Q9H609 Q9H609 ZNF576 Zinc finger protein 576 1 S(0.003)PQS(0.997)PGGNICHLGAPK;S(0.002)PQS(0.998)PGGNICHLGAPK 103.99 0.00073329 16631700.0 112531.0 113591.0 117115.0 114276.0 113464.0 114248.0 115344.0 107278.0 121812.0 95953.0 True False 110926.28730434219 113327.98701851013 107486.25677697365 122680.23825356067 106790.270598807 109361.87936509577 121315.94793747341 112262.52751759355 108092.24982277381 112538.34820066406 0.9856754526603905 1.0070166199386372 0.9551078232045652 1.090119414537815 0.9489233875051389 0.9717743428230845 1.0779965218714447 0.997549096041656 0.960492592534213 1.0 16.780057167716564 SPRPAS(ph)PASNVVVLPSGSTVYVK ddPTM_PC-9_AZD4547_30min_R2 2 SPRPASPASNVVVLPSGSTVYVK 23 1 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;Q7Z589-2 E9PMC9 C11orf30;EMSY Protein EMSY 1 S(0.296)PRPAS(0.677)PAS(0.027)NVVVLPSGSTVYVK;S(0.157)PRPAS(0.839)PAS(0.004)NVVVLPSGSTVYVK 106.1 1.0466e-06 31116000.0 84670.0 67276.0 91432.0 145186.0 133256.0 98701.0 74156.0 106787.0 84988.0 80407.0 True False 111593.29875459406 89021.65134611547 90219.55193939243 111715.61080133972 114755.70456599203 92529.21086705182 80755.74034079265 90285.52287113968 89480.29217355928 77591.97540398588 1.4382066982259294 1.1473048711882963 1.162743330990873 1.439783047405195 1.4789635650917718 1.1925100551351424 1.0407743831798906 1.163593559785845 1.1532158023774544 1.0 16.243619835524925 -6.993249980058185 24.74943382583427 1.1049735019494826 1.32111550162417 0.505038241565264 0.11353625820101894 148.56180968684427 544708.609773105 0.04292246464930263 0.03776477056312388 1.0156639080790918e-07 6.993249980058185 0.2161419996746874 SPRPAS(ph)PASNVVVLPSGSTVYVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPRPASPASNVVVLPSGSTVYVK 23 1 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;Q7Z589-2 E9PMC9 C11orf30;EMSY Protein EMSY 1 S(0.296)PRPAS(0.623)PAS(0.08)NVVVLPSGSTVYVK 79.94 9.5478e-05 10841000.0 51303.0 42605.0 48860.0 72567.0 68413.0 58983.0 58432.0 53250.0 58316.0 50184.0 True False 59987.58461956218 46834.54283336416 50025.00770258186 68501.30625538828 55007.963756829675 55889.8276463628 52896.89794895454 51852.2439230387 59168.76117696699 59281.96194367456 1.0119028225914326 0.7900302435648631 0.8438487199548491 1.1555168555398565 0.9279039011747666 0.9427796552932117 0.892293308362725 0.8746715227189167 0.9980904686181755 1.0 15.855305574149533 SPRPAS(ph)PASNVVVLPSGSTVYVK ddPTM_PC-9_Lapatinib_30min_R1 2 SPRPASPASNVVVLPSGSTVYVK 23 1 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;Q7Z589-2 E9PMC9 C11orf30;EMSY Protein EMSY 1 S(0.116)PRPAS(0.806)PAS(0.077)NVVVLPSGSTVYVK;S(0.005)PRPAS(0.955)PAS(0.04)NVVVLPSGSTVYVK 91.337 8.316e-06 18334300.0 109321.0 72152.0 90674.0 72423.0 76696.0 84893.0 71871.0 71319.0 87148.0 68001.0 True False 107762.06249298374 71984.93647700573 83219.1337317621 77749.22901604563 72184.89207013759 81262.32428524856 75592.1287124962 74632.74110280977 77332.47453087616 79754.88224436293 1.3511657150067493 0.9025771771118578 1.0434362309856462 0.9748522827458747 0.9050843037918173 1.0189009374531697 0.9478056588546846 0.9357764565953554 0.9696268410745728 1.0 16.28328521659796 -4.75563701192102 24.993237801590556 0.9662511023426726 1.3511663369304954 0.8750607266288224 0.04361036106833525 58.500796338826504 251962.02717856987 0.01039399644817998 0.09057749605951866 1.7553470271355097e-05 4.75563701192102 0.38491523458782273 SPRPGS(ph)SAPEHSPR ddPTM_PC-9_AZD4547_30min_R2 1 SPRPGSSAPEHSPR 14 1 O75385 O75385 ULK1 Serine/threonine-protein kinase ULK1 1 S(0.083)PRPGS(0.435)S(0.435)APEHS(0.047)PR 54.292 0.037273 1581600.0 832.2 0.0 2104.7 2278.4 3002.3 1076.5 996.77 2558.8 1047.7 2259.7 True False 1096.8222891646765 0.0 2076.79030281345 1753.150080929098 2585.482468470298 1009.1862848236746 1085.4805990006464 2163.396255374462 1103.0792830780583 2180.5885907991496 0.5029936842706809 0.0 0.9523989585088771 0.8039802135654565 1.1856810034591447 0.4628045331805687 0.49779247840732566 0.9921157363212714 0.5058630902373923 1.0 11.090501888661201 -5.267289327707714 24.99911951052548 0.7908672199817198 0.25149683399344 0.4186747596792053 0.2583847126034225 407.31454549770854 1740621.0108456835 0.06667466410954423 0.14496893143841322 5.4039419148772824e-06 5.267289327707714 -0.5393703859882798 SPRPT(ph)SAPAITQGQVAEGGVLDASAK ddPTM_PC-9_AZD4547_30min_R2 1 SPRPTSAPAITQGQVAEGGVLDASAK 26 1 A0A2R8Y5C8;Q4VB86;A0A2U3TZH6;A0A3B3IU06;A0A2R8Y5Z6;A0A2R8Y5G2;A0A2R8Y570;A0A2R8YCW8;A0A2R8Y6G5;A0A2R8YFR9;A0A2R8Y4N6;A0A2R8YD30;A0A3B3IUD6;A0A2R8Y7Y3;A0A2R8Y7N0;A0A2R8Y420;A0A3B3ITP0;A0A2R8Y6D0;A0A1B0GWG0;P11171-3;P11171-4;P11171-7;P11171-6;P11171-5;P11171-2;P11171 A0A2R8Y5C8 EPB41 Protein 4.1 1 S(0.04)PRPT(0.477)S(0.477)APAIT(0.005)QGQVAEGGVLDASAK 94.35600000000001 3.5841999999999997e-09 11643000.0 27407.0 22763.0 36053.0 53123.0 40327.0 41384.0 28242.0 40190.0 26414.0 28759.0 True False 36121.85589898614 30120.694595273613 35574.913663388266 40876.31309216843 34728.29214468963 38796.25193789405 30755.483287996496 33979.558974323714 27810.19011475025 27752.156163558328 1.3015873680625278 1.0853461049208653 1.2818792692620435 1.472905847432625 1.2513727560488344 1.397954512407863 1.1082195958662797 1.224393476819025 1.0020911510748893 1.0 14.760312243467316 -8.021956799469843 1.2564247654339056 0.9916414867290836 1.2882458940979162 0.5018671788321016 0.10775141924548937 0.40172620659238206 1.148675727117485 0.1011412257063254 0.03452619932470437 9.50699357771976e-09 8.021956799469843 0.29660440736883265 SPRPT(ph)SAPAITQGQVAEGGVLDASAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPRPTSAPAITQGQVAEGGVLDASAK 26 1 A0A2R8Y5C8;Q4VB86;A0A2U3TZH6;A0A3B3IU06;A0A2R8Y5Z6;A0A2R8Y5G2;A0A2R8Y570;A0A2R8YCW8;A0A2R8Y6G5;A0A2R8YFR9;A0A2R8Y4N6;A0A2R8YD30;A0A3B3IUD6;A0A2R8Y7Y3;A0A2R8Y7N0;A0A2R8Y420;A0A3B3ITP0;A0A2R8Y6D0;A0A1B0GWG0;P11171-3;P11171-4;P11171-7;P11171-6;P11171-5;P11171-2;P11171 A0A2R8Y5C8 EPB41 Protein 4.1 1 S(0.033)PRPT(0.482)S(0.482)APAIT(0.004)QGQVAEGGVLDASAK 78.45100000000001 3.6375e-05 9516300.0 41608.0 66442.0 77299.0 99686.0 83752.0 103400.0 96928.0 62080.0 95040.0 77464.0 True False 48651.41260454056 73037.92266011923 79142.10131809009 94100.9166063725 67341.39681876262 97977.52197470312 87746.27814204979 60450.4657791971 96429.78020198489 91507.60999531331 0.5316652091233975 0.798162280315921 0.8648690674157424 1.0283397917527517 0.7359103447485035 1.070703540172464 0.9588959666474061 0.6606058860273277 1.0537897362517028 1.0 16.481604105962205 -4.657266846999297 1.6322708431772823 0.9151890286565337 0.3006282219127793 0.46305033696507436 0.12805997705684583 1.268741377942857 2.5960060319150178 0.03434894087323808 1.362315854313726 2.2015733172482746e-05 4.657266846999297 -0.6145608067437545 SPRPT(ph)SAPAITQGQVAEGGVLDASAK ddPTM_PC-9_Lapatinib_30min_R1 2 SPRPTSAPAITQGQVAEGGVLDASAK 26 1 A0A2R8Y5C8;Q4VB86;A0A2U3TZH6;A0A3B3IU06;A0A2R8Y5Z6;A0A2R8Y5G2;A0A2R8Y570;A0A2R8YCW8;A0A2R8Y6G5;A0A2R8YFR9;A0A2R8Y4N6;A0A2R8YD30;A0A3B3IUD6;A0A2R8Y7Y3;A0A2R8Y7N0;A0A2R8Y420;A0A3B3ITP0;A0A2R8Y6D0;A0A1B0GWG0;P11171-3;P11171-4;P11171-7;P11171-6;P11171-5;P11171-2;P11171 A0A2R8Y5C8 EPB41 Protein 4.1 1 S(0.035)PRPT(0.482)S(0.482)APAITQGQVAEGGVLDASAK;S(0.092)PRPT(0.45)S(0.45)APAIT(0.007)QGQVAEGGVLDASAK 88.244 6.187899999999999e-07 20907000.0 95648.0 120073.0 150677.0 106357.0 146015.0 168847.0 160656.0 158498.0 194916.0 130702.0 True False 94284.04198030522 119794.9783457629 138288.91869003995 114178.84857655143 137426.68477653526 161625.80741158107 168973.98158415486 165862.39570539675 172962.50752352623 153293.66655053187 0.6150550384886602 0.7814737623636497 0.9021176269174451 0.744837351378202 0.89649290716935 1.0543541103069811 1.102289386029227 1.0819911835739262 1.128308242705583 1.0 17.22593856657445 -6.61139660651331 2.1112407705632923 1.0870026004145852 0.7695193606255746 0.8053976443268107 0.07247368010172622 0.13946640525698403 1.2668561511964622 0.027841701277932233 0.02831601426762712 2.446827728623524e-07 6.61139660651331 -0.3174832397890106 SPRS(ph)PQLSDFGLER ddPTM_PC-9_AZD4547_30min_R2 1 SPRSPQLSDFGLER 14 1 Q8IX90;Q8IX90-3 Q8IX90 SKA3 Spindle and kinetochore-associated protein 3 1 S(0.175)PRS(0.825)PQLSDFGLER 54.95 0.036101 5748800.0 2521.1 1309.9 2595.1 11854.0 9848.5 5814.5 2463.0 4965.4 1786.2 5632.5 True False 3322.757357862371 1733.2995585093743 2560.687278391783 9121.243442474342 8481.205772484334 5450.918395826528 2682.202228536767 4198.111523540856 1880.6148854004277 5435.30788939957 0.6113282679611791 0.3188962969126022 0.47112092460960076 1.678146597778466 1.560391047768453 1.0028720555936497 0.49347751463497425 0.7723778687364508 0.3459996974721843 1.0 12.408146045384555 -11.193437423025903 2.7129169747009145 1.0221876216954238 0.8253268606288826 0.014528361674439494 0.45492355996058503 229260581.2059242 202997510.3196162 35360777.90574275 0.1277907365794209 6.405640730336499e-12 11.193437423025903 -0.19686076106654116 SPRS(ph)PQLSDFGLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPRSPQLSDFGLER 14 1 Q8IX90;Q8IX90-3 Q8IX90 SKA3 Spindle and kinetochore-associated protein 3 1 S(0.005)PRS(0.99)PQLS(0.005)DFGLER 70.628 0.034282 0.0 6682.5 7812.2 8171.7 11572.0 9143.0 9370.1 10109.0 12266.0 8776.7 6024.7 True False 7813.71526460878 8587.74358696885 8366.544319344826 10923.658356930198 7351.494783574671 8878.715460881684 9151.40233717794 11944.030496901285 8905.042633614898 7116.930418501042 1.0979052491923187 1.206663980393051 1.1755832679767826 1.5348833998058005 1.0329586424596564 1.2475484427669459 1.2858636798510945 1.6782559045191452 1.2512476742031244 1.0 12.79703941561727 -7.529206178848749 24.998364942836414 1.3752629860454604 1.2237554061728657 0.014214985589898088 0.20005696456622574 386.9127593242289 1528583.4718609373 0.08998584395894717 0.05212646640183597 2.956608500153612e-08 7.529206178848749 -0.15150757987259467 SPS(ph)AGDVHILTGFAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSAGDVHILTGFAK 15 0 A0A3B3ITL0;Q9Y2H2;A0A3B3IRJ9;Q9Y2H2-4 A0A3B3ITL0 INPP5F Phosphatidylinositide phosphatase SAC2 1 S(0.012)PS(0.988)AGDVHILTGFAK 65.51100000000001 0.033757999999999996 4999000.0 8182.1 6611.2 8098.9 13345.0 14684.0 13825.0 11891.0 13056.0 11689.0 9144.7 True False 9567.167926158694 7267.516244101329 8292.00849124929 12597.322915073748 11806.775609975984 13099.992662478435 10764.598396615189 12713.293833975466 11859.929511584596 10802.561720594638 0.8856388117569635 0.6727585948660778 0.7675964929171307 1.1661421837616046 1.0929607175922775 1.2126746415624583 0.996485710985842 1.1768776853862446 1.0978812080262528 1.0 13.399085853359894 -5.75581285465128 24.99918312560031 1.1128360603242196 0.7650739165917888 0.77415297615583 0.08176984436315808 54.982244750614306 244287.93183987742 0.02097084335577823 0.035064564025531424 1.7546364435408075e-06 5.75581285465128 -0.34776214373243075 SPS(ph)AGDVHILTGFAK ddPTM_PC-9_Lapatinib_30min_R1 1 SPSAGDVHILTGFAK 15 0 A0A3B3ITL0;Q9Y2H2;A0A3B3IRJ9;Q9Y2H2-4 A0A3B3ITL0 INPP5F Phosphatidylinositide phosphatase SAC2 1 S(0.18)PS(0.82)AGDVHILTGFAK 60.093 0.029612 8367600.0 13775.0 24447.0 19968.0 17045.0 19817.0 24012.0 24067.0 23136.0 20246.0 16041.0 True False 13578.565973974373 24390.39447351919 18326.308118709025 18298.546160453152 18651.403021721035 22985.0627347059 25313.07149926459 24210.983022120472 17965.682280168436 18813.66547671104 0.7217395244314796 1.2964190579295374 0.9740955658744276 0.9726199385815836 0.9913752875434685 1.2217216662621395 1.3454619744673892 1.2868828273836714 0.9549272736037375 1.0 14.199493336857767 -6.7584730284849694 24.86781471921939 1.1912078897447211 1.0062156803435374 0.18631732809282775 0.1714040281963407 114.7796033245483 962233.2965484406 0.056506813006438346 0.05415367819391307 1.7439216589770342e-07 6.7584730284849694 -0.18499220940118377 SPS(ph)ASSVGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSASSVGSR 10 0 O15164-2;O15164 O15164-2 TRIM24 Transcription intermediary factor 1-alpha 1 S(0.075)PS(0.909)AS(0.007)S(0.007)VGS(0.002)R;S(0.017)PS(0.967)AS(0.011)S(0.005)VGSR 100.09 0.0041234999999999996 9665400.0 19006.8 23879.5 22245.7 23497.1 27116.0 23522.2 24218.0 23999.0 24436.0 20523.5 True False 22224.275838588266 26250.09894588241 22776.121855287045 22180.633665626017 21802.8144538347 22288.654423533488 21923.89571686371 23369.05167904237 24793.33027162985 24244.248086063395 0.9166824130695027 1.0827351235104736 0.939444348797095 0.91488230886304 0.899298438806517 0.9193378299220563 0.904292665173084 0.9639008640765344 1.0226479362699679 1.0 14.565354890065333 -8.1009493459573 4.511139347831756 1.0097535787951417 0.9412888983692964 0.24057105595901096 0.05024629080479833 0.370571133614282 12.20757721824441 0.0391609804020289 0.01398389902358265 7.925937694569385e-09 8.1009493459573 -0.0684646804258453 SPS(ph)ASSVGSR ddPTM_PC-9_Lapatinib_30min_R1 3 SPSASSVGSR 10 0 O15164-2;O15164 O15164-2 TRIM24 Transcription intermediary factor 1-alpha 1 S(0.155)PS(0.759)AS(0.071)S(0.015)VGSR;S(0.406)PS(0.57)AS(0.023)S(0.002)VGSR;S(0.068)PS(0.919)AS(0.01)S(0.002)VGSR 92.943 0.007109699999999999 12758900.0 24397.4 24742.9 26897.3 21837.300000000003 25450.4 25774.9 20330.8 26791.399999999998 28428.9 21481.4 True False 24049.48860206479 24685.609335249257 24685.907820580538 23443.287889097308 23953.457509411568 24672.56761122653 21383.4293446316 28036.22625081424 25226.93791241137 25194.431367833724 0.9545557211015008 0.9798041866809468 0.9798160339549307 0.9304948203366821 0.9507441211788358 0.9792865435624211 0.8487363351225418 1.112794563270386 1.0012902273563176 1.0 14.620817274949633 -7.773410739863828 24.999977432573505 1.0427817589797053 0.949633027913375 0.4469195645204166 0.046611352745728626 202.77905608301867 423460.1521156863 0.024062136643406565 0.011700162799810317 1.6849586991641177e-08 7.773410739863828 -0.09314873106633026 SPS(ph)DNSLNTTGIICR ddPTM_PC-9_AZD4547_30min_R2 1 SPSDNSLNTTGIICR 15 0 P48553 P48553 TRAPPC10 Trafficking protein particle complex subunit 10 1 S(0.485)PS(0.515)DNSLNTTGIICR 158.17 2.3988999999999998e-14 0.0 4499.9 3342.7 5604.7 8712.2 5569.7 4847.4 3290.5 6299.0 5328.1 4254.8 True False 5930.774596265469 4423.162404938763 5530.378015954075 6703.736892148218 4796.443295020156 4544.291311708573 3583.348125456854 5325.634286620184 5609.732488468267 4105.840747060328 1.4444726334093072 1.0772854276205497 1.346953853461968 1.6327318337779941 1.1682000327105433 1.1067870362390855 0.8727440605246162 1.2970873968828907 1.3662810698356203 1.0 12.003461955488541 -6.4937439416732445 24.647971933704618 1.131862009474193 1.3580939285589435 0.2960922104826824 0.18145934941794709 868.5446624110125 734787.2691395242 0.059252163358700656 0.0670610345394487 3.208160285747149e-07 6.4937439416732445 0.2262319190847506 SPS(ph)DNSLNTTGIICR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSDNSLNTTGIICR 15 0 P48553 P48553 TRAPPC10 Trafficking protein particle complex subunit 10 1 S(0.146)PS(0.852)DNS(0.002)LNTTGIICR 145.46 1.5821e-09 0.0 7969.7 4330.3 4217.0 5128.8 4631.9 4262.3 5590.8 4353.4 6093.0 4852.6 True False 7856.050616536016 4320.273456402841 3870.29453809074 5505.989061175251 4359.460748665778 4080.0113649065893 5880.264268005508 4555.674856868056 5406.742177865564 5691.36544431694 1.3803454888634155 0.759092611196986 0.680029173307679 0.9674284870730283 0.7659780049827721 0.7168774180509964 1.0331904224982058 0.8004537577914774 0.9499903372510399 1.0 12.47455910299694 -4.755952097931109 24.998931872344375 0.8432211721632553 1.3803463388128252 0.6328938703345219 0.12040043452010835 109.72412573439541 499827.95747575926 0.02919564394426808 0.24724022929745593 1.7540739630567606e-05 4.755952097931109 0.5371251666495699 SPS(ph)DSGYSYETIGK ddPTM_PC-9_Lapatinib_30min_R1 1 SPSDSGYSYETIGK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.204)PS(0.755)DS(0.04)GYSYETIGK 209.53 4.3579e-11 65478000.0 71115.0 66814.0 72674.0 71378.0 80042.0 82398.0 81282.0 77041.0 86484.0 80346.0 True False 70100.88705910635 66659.29628803994 66699.0242497525 76627.37623002796 75334.08692862678 78874.02961911945 85490.38424411944 80620.6061119978 76743.26120310604 94233.69904568471 0.7439046516164167 0.7073827830500781 0.7078043728010366 0.8131631996413389 0.7994389235649622 0.837004494335738 0.9072166869165723 0.8555390155374538 0.8143929611199995 1.0 16.52395545586287 -2.170945795099065 0.07599198495135749 1.177944561882624 1.691205929940128e-08 0.7977017021322322 0.038455394528024954 84.34971367993414 0.534425028818137 1.4811397724607527 10.646210782045042 0.006746122217373589 2.170945795099065 -1.1779445449705648 SPS(ph)EARQDVDLCLVSSCEYK ddPTM_PC-9_AZD4547_30min_R2 1 SPSEARQDVDLCLVSSCEYK 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.198)PS(0.802)EARQDVDLCLVSSCEYK 104.16 7.6526e-05 16588000.0 33098.0 18562.0 41109.0 61374.0 54268.0 43303.0 28837.0 38030.0 28926.0 46073.0 True False 43622.47551883254 24561.80350030615 40563.867799856576 47225.17251884767 46733.824933866075 40595.25656453282 31403.437135328775 32153.337342461593 30454.969306400602 44459.99829352978 0.9811623300305182 0.552447243433219 0.9123677318215236 1.0621946543286374 1.0511432012508017 0.9130737319538001 0.7063301471133634 0.7231969990232958 0.6849970867145239 1.0 15.44022027254062 -7.250423916639347 23.867000850774666 0.7555641424002484 0.908878173945145 0.14235896988687746 0.1562828495106351 739.1695812215398 1601547.6998516626 0.06346064866822178 0.048619386528959446 5.6179268930430735e-08 7.250423916639347 0.15331403154489665 SPS(ph)EARQDVDLCLVSSCEYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSEARQDVDLCLVSSCEYK 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.26)PS(0.466)EARQDVDLCLVS(0.135)S(0.135)CEY(0.004)K;S(0.444)PS(0.556)EARQDVDLCLVS(0.001)SCEYK 65.808 0.0029587 16041800.0 22551.2 7632.200000000001 20503.7 30149.0 37089.0 36159.0 28848.0 33933.0 36758.0 24812.0 True False 26368.672753497274 8389.874376547406 20992.585968715262 28459.849274376793 29821.676695614246 34262.758385718465 26115.30859856656 33042.29470498542 37295.51621069609 29310.219188316056 0.8996409267389112 0.28624399983647564 0.7162207090243646 0.9709872550431746 1.0174498015184434 1.1689697086733708 0.8909967008700131 1.1273301810774954 1.2724407132909883 1.0 14.839116136410551 -5.758281740378188 2.710100255531784 1.0756081681948932 0.5750960222407296 0.5847036641115004 0.1692610780198875 0.1709499782001323 2.56229589527208 0.04767869328116408 0.08561505005567915 1.744689950916225e-06 5.758281740378188 -0.5005121459541636 SPS(ph)EARQDVDLCLVSSCEYK ddPTM_PC-9_Lapatinib_30min_R1 1 SPSEARQDVDLCLVSSCEYK 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.169)PS(0.831)EARQDVDLCLVSSCEYK 117.27 7.808099999999999e-06 8369100.0 29697.0 22150.0 32148.0 27478.0 23170.0 25433.0 14675.0 17053.0 31423.0 14084.0 True False 29273.515334237196 22098.713035891946 29504.915534868665 29498.823783920874 21807.18615397268 24345.28987721869 15434.799694673537 17845.344635037192 27883.810841140614 16518.400634249647 1.7721761314797504 1.3378240136682449 1.7861847637774608 1.785815978016498 1.320175399351747 1.4738285150161925 0.9344003718296222 1.0803312639140275 1.6880454384503578 1.0 14.011786386601125 -6.635915004382839 1.8899596336909816 1.2000284802096866 1.6477326968595676 0.4157194271791028 0.24303771100347915 0.34972152340211377 2.560197904358942 0.09472561084122424 0.09491925684688503 2.3125173278272996e-07 6.635915004382839 0.447704216649881 SPS(ph)FASEWDEIEK ddPTM_PC-9_AZD4547_30min_R2 2 SPSFASEWDEIEK 13 0 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 S(0.054)PS(0.944)FAS(0.002)EWDEIEK;S(0.151)PS(0.803)FAS(0.046)EWDEIEK 147.56 0.00011049 43873000.0 78184.0 79806.0 98085.0 118913.0 119352.0 119452.0 100433.0 109874.0 102695.0 102339.0 True False 103044.88567177491 105601.72880861058 96784.32881239944 91499.445037536 102782.03496548205 111982.6475566722 109371.34243549843 92895.49795334286 108123.24804400229 98756.14275956723 1.043427606550502 1.0693180784278877 0.9800335058451161 0.9265190243436455 1.0407659928123794 1.1339309578879195 1.107489006549953 0.9406553897058053 1.0948508621609525 1.0 16.59158286801153 SPS(ph)FASEWDEIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPSFASEWDEIEK 13 0 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 S(0.008)PS(0.992)FASEWDEIEK;S(0.018)PS(0.976)FAS(0.006)EWDEIEK;S(0.049)PS(0.948)FAS(0.004)EWDEIEK;S(0.062)PS(0.936)FAS(0.002)EWDEIEK 132.08 0.00044348 16689000.0 32180.4 37267.9 32383.6 41487.8 41086.7 39188.6 37895.6 35005.8 32828.8 28856.300000000003 True False 37627.90612812815 40967.610817029316 33155.74783948689 39163.37307126239 33036.05607834382 37133.4808284125 34305.85442761504 34086.93484171099 33308.859094012194 34087.71876365487 1.1038552151001642 1.2018290546538406 0.9726596276321762 1.1488997941692507 0.9691483407087846 1.0893507156015703 1.0063992450029469 0.9999770028041678 0.977151311443196 1.0 15.056964433457198 -4.8880471120007 0.3651897359419307 0.9869387319277741 1.2562860266534772 0.36615137391150376 0.06264635111788971 5.947043598935471 0.6715075981353849 0.054610306233325634 0.7054682746126067 1.2940554554885317e-05 4.8880471120007 0.26934729472570307 SPS(ph)FASEWDEIEK ddPTM_PC-9_Lapatinib_30min_R1 2 SPSFASEWDEIEK 13 0 Q92625;A0A3B3ISP1 Q92625 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 S(0.01)PS(0.98)FAS(0.01)EWDEIEK;S(0.076)PS(0.899)FAS(0.025)EWDEIEK 193.45 1.4387e-06 26916000.0 74646.0 69457.0 62718.9 61809.4 68467.0 72474.0 64925.0 60038.6 67942.0 58253.9 True False 73581.53435159994 69296.17658392535 57562.39414395526 66355.06946611399 64439.90567130116 69374.45596514562 68286.49881953518 62828.212537685155 60289.65649902225 68323.00899655734 1.0769656581622096 1.0142436289276582 0.8425037917585818 0.971196533066298 0.9431655106780814 1.0153893539530916 0.9994656239887795 0.9195761934438652 0.8824209791764311 1.0 16.06008389327861 -5.008052840987248 18.81213881345462 0.9475564371821206 1.0612873450982325 0.39197825310709034 0.051895779867359985 14.314122468060804 33464.23729937485 0.013386472703763268 0.04322362798431476 9.816285001605973e-06 5.008052840987248 0.11373090791611196 SPS(ph)FGAGEGLLR ddPTM_PC-9_AZD4547_30min_R2 1 SPSFGAGEGLLR 12 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 S(0.01)PS(0.99)FGAGEGLLR 111.31 0.0010880999999999998 22477000.0 6754.7 7000.1 7043.9 15547.0 14207.0 14434.0 12691.0 7410.8 6168.7 13312.0 True False 8902.554093511939 9262.74543058361 6950.493283597502 11962.879348755572 12234.603280670655 13531.439698230308 13820.474414275315 6265.631143242558 6494.764888349354 12845.950931857455 0.6930241397259236 0.7210634292251861 0.5410649099056226 0.9312568148682633 0.9524093113518999 1.053362243870391 1.0758623077098233 0.4877514460766029 0.5055884864266912 1.0 13.649026070402858 -5.76927489571984 24.99511894693593 0.8578365517152192 0.6586520784005117 0.18231698362316606 0.20006389965346924 341.72970854262536 1090112.4021445198 0.06262864553522532 0.09483830700582772 1.701081432699607e-06 5.76927489571984 -0.19918447331470757 SPS(ph)FGAGEGLLR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSFGAGEGLLR 12 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 S(0.259)PS(0.741)FGAGEGLLR 105.95 0.0017295000000000001 18196000.0 16635.0 15153.0 18805.0 14106.0 14628.0 15407.0 14353.0 15166.0 16783.0 14149.0 True False 16397.78184951462 15117.914159497539 17258.9254893992 15143.402296236565 13767.609799754526 14748.07852547118 15096.12811023164 15870.667726205014 14892.72180717509 16594.63579764259 0.9881374951202042 0.9110121092049015 1.0400303869188245 0.9125480354553979 0.8296421788124048 0.8887256523922188 0.9096992723622277 0.9563733678602081 0.8974419197130394 1.0 14.018429346494996 -5.959581522413382 24.781512953726995 0.9064834082197623 0.9734276665847243 0.2519195595764241 0.0510826457335708 186.97588450594003 114638.04779592289 0.014265702667067516 0.021159429699286983 1.0975352500768634e-06 5.959581522413382 0.0669442583649621 SPS(ph)FGGASEASAR ddPTM_PC-9_AZD4547_30min_R2 1 SPSFGGASEASAR 13 0 H7C2F7;Q8WVT3 H7C2F7 TRAPPC12 Trafficking protein particle complex subunit 12 1 S(0.048)PS(0.952)FGGASEASAR 116.98 0.00026569 10692000.0 10157.0 8940.1 11638.0 13970.0 12198.0 15732.0 10338.0 12087.0 9231.7 12366.0 True False 13386.714721275666 11829.812491815912 11483.672515865883 10749.432334348448 10504.518252806407 14748.275553038604 11258.061972640311 10219.23188162854 9719.668815110914 11933.070103917456 1.1218164818189578 0.9913469366053882 0.9623401535281316 0.9008102894509572 0.8802863103400292 1.235916275074673 0.9434338250425974 0.8563791038379731 0.8145153535903628 1.0 13.542677642522177 -7.5222262282645325 24.848490851186654 0.8812495756679575 1.007986786328892 0.2164575943560627 0.10688190875815233 36.15049612160372 1376849.998175349 0.05101253923008844 0.02990458590205794 3.004510815708047e-08 7.5222262282645325 0.12673721066093457 SPS(ph)FGGASEASAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSFGGASEASAR 13 0 H7C2F7;Q8WVT3 H7C2F7 TRAPPC12 Trafficking protein particle complex subunit 12 1 S(0.351)PS(0.649)FGGASEASAR;S(0.169)PS(0.83)FGGASEASAR 108.32 0.00090997 15038300.0 12587.6 19366.4 20544.5 21047.4 29081.8 22667.6 20663.5 23760.1 22361.0 15360.099999999999 True False 14718.432063567447 21288.968203921224 21034.358795450138 19868.18241459148 23383.430055448098 21478.87115197079 18706.103689215204 23136.4225509069 22687.987322144167 18144.7645395153 0.8111668813069436 1.1732843464327432 1.1592522322150798 1.0949815508116931 1.2887149901848622 1.1837503377458847 1.0309367006927772 1.2751018345000216 1.2503875303939451 1.0 14.14726571496258 -4.761004125291143 24.959682038977615 1.1688114671279244 0.8111664727869785 0.5628123810500003 0.09253179414393324 7.3501441558518295 421012.054969123 0.022391930708322103 0.12802433936191124 1.7337875287161852e-05 4.761004125291143 -0.3576449943409459 SPS(ph)FGGASEASAR ddPTM_PC-9_Lapatinib_30min_R1 2 SPSFGGASEASAR 13 0 H7C2F7;Q8WVT3 H7C2F7 TRAPPC12 Trafficking protein particle complex subunit 12 1 S(0.022)PS(0.974)FGGAS(0.002)EAS(0.002)AR;S(0.071)PS(0.929)FGGASEASAR 111.88 0.00051732 16827600.0 23427.0 16992.0 21836.6 17954.2 17562.0 17933.0 17635.6 12327.4 22810.0 18674.7 True False 23092.92668401436 16952.656067985357 20041.279039713616 19274.61176145543 16529.03768822047 17166.047393864777 18548.68507634648 12900.176007386239 20240.897600051463 21902.59701252638 1.0543465083527408 0.7740020993076717 0.915018389291998 0.8800149019055608 0.7546610878503265 0.7837448401231731 0.8468714949984353 0.5889792886208178 0.9241323112722857 1.0 14.418814321291851 -6.127641869370821 5.399391617172248 0.7960505376893646 0.8998830839316243 0.10417510986285539 0.12055294920664929 0.4529959838477791 18.024903611013688 0.033862657955554085 0.04424068453738087 7.453463527210984e-07 6.127641869370821 0.10383254624225968 SPS(ph)GAGEGASCSDGPR ddPTM_PC-9_AZD4547_30min_R2 1 SPSGAGEGASCSDGPR 16 0 Q7Z2K8;Q7Z2K8-2 Q7Z2K8 GPRIN1 G protein-regulated inducer of neurite outgrowth 1 1 S(0.093)PS(0.907)GAGEGASCSDGPR 63.31 0.033939 5439700.0 1604.9 2989.7 2781.5 4957.3 5160.8 3654.4 3903.5 3678.5 3149.1 3921.6 True False 2115.2248160062345 3956.0620582300025 2744.615492600185 3814.4710745215134 4444.312001892385 3425.8897903015663 4250.903937918501 3110.072348520773 3315.554996984933 3784.3059776421414 0.5589465620652988 1.0453864147356489 0.725262573590905 1.0079711040961246 1.174406094049897 0.9052887928571012 1.1232981590370974 0.8218342720951286 0.8761329069513376 1.0 11.885813026241243 -4.7541884815654205 24.996481822189892 0.962400065367708 0.5589458553763533 0.4683479371048378 0.129579574745641 236.7419662791033 816066.0261063053 0.03246007719743601 0.32437943594832525 1.7612115238057103e-05 4.7541884815654205 -0.4034542099913546 SPS(ph)GSQRPSVSDDTEHLVNGR ddPTM_PC-9_AZD4547_30min_R2 1 SPSGSQRPSVSDDTEHLVNGR 21 1 P16144-4;P16144-2;P16144-3 P16144-4 ITGB4 Integrin beta-4 1 S(0.206)PS(0.526)GS(0.131)QRPS(0.131)VS(0.005)DDTEHLVNGR 53.037 0.012333 25820000.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPS(ph)GSQRPSVSDDTEHLVNGR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSGSQRPSVSDDTEHLVNGR 21 1 P16144-4;P16144-2;P16144-3 P16144-4 ITGB4 Integrin beta-4 1 S(0.342)PS(0.563)GS(0.095)QRPSVSDDTEHLVNGR 82.755 0.00028571 20932000.0 0.0 0.0 1532.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 1406.2284304630396 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPS(ph)IVASNQGR ddPTM_PC-9_AZD4547_30min_R2 1 SPSIVASNQGR 11 0 Q8TED9;Q8TED9-4 Q8TED9 AFAP1L1 Actin filament-associated protein 1-like 1 1 S(0.432)PS(0.568)IVASNQGR 75.89 0.021223 4305200.0 9343.6 7078.9 12339.0 25001.0 19544.0 14649.0 12168.0 16816.0 10823.0 11797.0 True False 12314.670441046701 9367.015989565629 12175.376797840625 19237.405711599546 16830.652953996443 13732.995714242466 13250.928427460572 14217.473593237806 11395.081684407578 11383.990620727342 1.0817533895912412 0.8228235863538647 1.0695174656655435 1.6898648595663053 1.4784492990842877 1.2063428521487172 1.1639967801215518 1.2489006770043727 1.000974268518813 1.0 13.474718757890175 -5.532654724802212 24.956211193345574 1.2777945535117046 0.9507588957560746 0.26772487926300104 0.20402957725811333 232.12721994158605 592574.4867453632 0.05780878311366659 0.10028061911997789 2.9332243066905656e-06 5.532654724802212 -0.3270356577556299 SPS(ph)KPLPEVTDEYKNDVK ddPTM_PC-9_AZD4547_30min_R2 1 SPSKPLPEVTDEYKNDVK 18 2 P05455;E9PGX9;E9PFL9;E7ERC4 P05455 SSB Lupus La protein 1 S(0.147)PS(0.852)KPLPEVT(0.001)DEY(0.001)KNDVK 45.723 0.032456 7036300.0 15221.0 15131.0 15914.0 18562.0 14552.0 22226.0 16600.0 21467.0 16373.0 14952.0 True False 20060.961383532256 20021.799847167986 15702.969961977129 14282.81768004123 12531.705985804136 20836.204706447756 18077.367841538897 18149.76841258541 17238.44335385802 14428.535031034604 1.3903671675871987 1.3876529948537897 1.0883273962464879 0.9899007521775463 0.8685362691949984 1.444097038377824 1.25289004064903 1.2579079146667862 1.1947466126519104 1.0 13.816637206006924 -3.9072137609341477 0.01596404774675145 5.415788690015638e-07 2.517157556823471 0.09486035947057225 0.17597307587856334 11420.189662909366 22.43529372418952 1522.0488710920133 2047.0221215145132 0.0001238186997488645 3.9072137609341477 2.517157015244602 SPS(ph)KPLPEVTDEYKNDVK ddPTM_PC-9_Lapatinib_30min_R1 1 SPSKPLPEVTDEYKNDVK 18 2 P05455;E9PGX9;E9PFL9;E7ERC4 P05455 SSB Lupus La protein 1 S(0.156)PS(0.844)KPLPEVTDEYKNDVK 72.797 0.0024553 9631600.0 39160.0 35587.0 33887.0 29307.0 37663.0 33929.0 34856.0 33841.0 29758.0 30710.0 True False 38601.5712189355 35504.60048795878 31100.941667602794 31462.334545286038 35447.736388307 32477.93576236203 36660.67312828216 35413.376402644346 26406.340674367893 36018.18258149717 1.0717245694335906 0.9857410325360997 0.8634789275453226 0.8735125508927953 0.9841622715999221 0.9017094543533746 1.0178379501889427 0.9832083093730688 0.7331391753212181 1.0 15.13643776660123 -4.929330312589918 3.639069670776795 0.9224240597865656 1.069661039009582 0.25611476847013526 0.08064707096375795 0.33932994542307504 8.404199691252037 0.02022232041348507 0.10810791996764356 1.1767106589137118e-05 4.929330312589918 0.14723697922301637 SPS(ph)LDNPTPFPNLGPSENPLKR ddPTM_PC-9_AZD4547_30min_R2 1 SPSLDNPTPFPNLGPSENPLKR 22 1 M0R0R8;M0R0X9;M0QXC8;M0QX56;M0R3C2;M0QYT9;M0R205;M0QZB8;M0QZB7;Q14653-3;Q14653-2;Q14653;Q14653-4 M0R0R8 IRF3 Interferon regulatory factor 3 1 S(0.438)PS(0.475)LDNPT(0.087)PFPNLGPSENPLKR 54.303999999999995 0.0066005 13302000.0 28812.0 24075.0 27692.0 30371.0 26013.0 33139.0 34152.0 41626.0 34559.0 30892.0 True False 37973.61667317069 31856.77293771524 27324.785986368643 23369.435177272495 22401.543967064543 31066.813091288222 37191.46183880943 35193.65817032097 36385.71818640316 29810.48048279299 1.2738344386998248 1.0686433905720976 0.9166167583961243 0.7839335293760745 0.7514653774196969 1.0421439905747378 1.2475968597781186 1.1805800376359321 1.2205679880740428 1.0 14.863532008302089 -7.005668918825989 24.44149183060533 1.1726111407942656 0.9473141741776532 0.2873674532850268 0.15003646423898645 244.7991547372253 1055453.2268923617 0.05870059811373909 0.05016477200227221 9.87031655143788e-08 7.005668918825989 -0.22529696661661247 SPS(ph)LDNPTPFPNLGPSENPLKR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSLDNPTPFPNLGPSENPLKR 22 1 M0R0R8;M0R0X9;M0QXC8;M0QX56;M0R3C2;M0QYT9;M0R205;M0QZB8;M0QZB7;Q14653-3;Q14653-2;Q14653;Q14653-4 M0R0R8 IRF3 Interferon regulatory factor 3 1 S(0.428)PS(0.493)LDNPT(0.079)PFPNLGPSENPLKR 57.673 0.004845 15680000.0 57380.0 63487.0 69115.0 59036.0 65553.0 60941.0 54514.0 58544.0 54637.0 57185.0 True False 56561.75067779675 63339.99975212966 63432.631491615335 63377.70437832279 61697.30142215675 58334.69549040945 57336.46818094942 61264.16796537958 48483.20570688346 67069.35105577715 0.8433323088329583 0.9443955958281745 0.9457767295058902 0.9449577695423911 0.9199030622921516 0.8697668096101949 0.8548833003209837 0.9134450684401317 0.7228816880390445 1.0 16.033366022557228 -6.762421100792403 4.941571349710728 0.8651998291993895 0.9243297197074916 0.09847490795120728 0.06979274182031653 0.36928185440222666 24.38308975847548 0.023127321573147286 0.021634680615609272 1.728139906864989e-07 6.762421100792403 0.05912989050810202 SPS(ph)LGSDLTFATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSLGSDLTFATR 13 0 Q13425 Q13425 SNTB2 Beta-2-syntrophin 1 S(0.025)PS(0.862)LGS(0.113)DLT(0.001)FATR 115.37 0.0002904 8711500.0 36406.0 88327.0 39968.0 52153.0 47154.0 42947.0 60441.0 43280.0 45729.0 46994.0 True False 42568.81674872388 97095.52082719293 40920.98869948408 49231.0364923073 37914.51219782128 40694.78371612742 54715.59092505411 42143.94585895054 46397.700114231506 55513.64019570069 0.7668172470523861 1.7490389836606786 0.7371339468142687 0.8868277475365424 0.6829765092716368 0.7330591828002494 0.9856242669759497 0.7591637966881952 0.8357891853365584 1.0 15.760554677586738 -5.319679096868104 24.999975124472652 0.8181918159563382 1.25793449778537 0.33605310796420174 0.24167627044261472 227.76658295477569 97770.59120565705 0.05753257864942099 0.11976366428721807 4.789838860313139e-06 5.319679096868104 0.43974268182903176 SPS(ph)LNLLQNK ddPTM_PC-9_AZD4547_30min_R2 1 SPSLNLLQNK 10 0 O43353-2;O43353 O43353-2 RIPK2 Receptor-interacting serine/threonine-protein kinase 2 1 S(0.017)PS(0.983)LNLLQNK 144.28 0.0001326 17711000.0 17229.0 16062.0 18966.0 32695.0 28294.0 25673.0 20514.0 27129.0 27690.0 23394.0 True False 22707.46361453762 21253.727390470718 18714.498447835736 25157.672882714556 24365.86648999054 24067.66325153571 22339.70625911621 22936.836412401786 29153.636869744623 22574.98318057941 1.0058684621334373 0.9414725681281868 0.8289927969441531 1.1144049446892594 1.0793304382592752 1.0661209826388889 0.9895779802101646 1.0160289480141749 1.2914134480872896 1.0 14.462437292380557 -5.776161411301952 24.999823628107787 1.0759037038104626 0.9270473850214673 0.38099090004406133 0.08992681566746324 246.05019891585135 417822.93642251374 0.025317589663407143 0.037732376285005344 1.6743204769692424e-06 5.776161411301952 -0.1488563187889953 SPS(ph)LNLLQNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPSLNLLQNK 10 0 O43353-2;O43353 O43353-2 RIPK2 Receptor-interacting serine/threonine-protein kinase 2 1 S(0.008)PS(0.992)LNLLQNK;S(0.083)PS(0.917)LNLLQNK;S(0.44)PS(0.56)LNLLQNK;S(0.149)PS(0.851)LNLLQNK 134.56 0.00011174 26961000.0 78498.0 78836.0 80240.0 78611.0 95965.0 75237.0 81681.0 80686.0 73154.0 64845.0 True False 91786.16099382889 86662.31707102688 82153.2259118945 74206.68053030064 77161.34714051675 71291.4392728312 73943.58436077066 78568.07799388352 74223.73885622883 76600.88518726244 1.1982389076763766 1.1313487678264782 1.072484028233597 0.9687444257189874 1.007316651131174 0.9306868856482337 0.9653097895671101 1.0256810714629732 0.9689671166955536 1.0 16.22507344334322 -5.318515759520677 1.4667883650781388 0.9785527636533983 1.2010229210206875 0.8809429125796286 0.02743969681224159 0.16703957104048878 0.5972417364929387 0.00840658494923961 0.0402177382971823 4.8026865210878554e-06 5.318515759520677 0.22247015736728926 SPS(ph)LNLLQNK ddPTM_PC-9_Lapatinib_30min_R1 2 SPSLNLLQNK 10 0 O43353-2;O43353 O43353-2 RIPK2 Receptor-interacting serine/threonine-protein kinase 2 1 S(0.031)PS(0.969)LNLLQNK;S(0.054)PS(0.946)LNLLQNK 149.41 0.00015609 21226500.0 61266.0 43801.0 40718.0 37642.0 47891.0 44790.0 57317.0 51250.0 56427.0 57401.0 True False 60392.33560519158 43699.581475625426 37370.32321602535 40410.31825003092 45074.14553732867 42874.43611058958 60284.593805765064 53631.26209732341 50071.597057347855 67322.68636797524 0.8970577210050198 0.6491063240817571 0.555092573278568 0.6002481545248278 0.6695238703185501 0.6368497518985597 0.8954573422138702 0.7966298582350583 0.7437551850451178 1.0 16.038805125029416 -7.255417206816474 24.9193412634318 0.8420130866782533 0.6589820902798079 0.43593275533788167 0.10542847186634609 479.31438816235584 1983376.1122345477 0.04154006045778583 0.03133562411084864 5.553704819407163e-08 7.255417206816474 -0.18303099639844533 SPS(ph)LSPSPPSPLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSLSPSPPSPLEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.14)PS(0.549)LS(0.219)PS(0.091)PPS(0.001)PLEK 121.18 0.0012317 0.0 19275.0 26719.0 19308.0 27594.0 20778.0 20795.0 21760.0 17667.0 16598.0 17524.0 True False 22537.87680139681 29371.48574028067 19768.37594599776 26047.997640955036 16706.700056121015 19704.4735924947 19698.735271242665 17203.25996973381 16840.714349669008 20700.962480092338 1.0887356963750354 1.4188463830378217 0.9549496051214321 1.2582988673113544 0.8070494341597635 0.9518626784355588 0.9515854777374003 0.8310367204557666 0.813523253610278 1.0 14.337410226161749 -6.2607474051931105 24.99755578204011 0.8899828751329026 1.1811634086889669 0.5568016054072193 0.1257318998231367 45.998279048542194 1661687.2863291865 0.0365236775194584 0.04438736807055513 5.485959470920842e-07 6.2607474051931105 0.2911805335560642 SPS(ph)MPENLNRPR ddPTM_PC-9_Lapatinib_30min_R1 3 SPSMPENLNRPR 12 1 D6RJC2;P30307-4;P30307-3;P30307-2;P30307;H0Y999 D6RJC2 CDC25C M-phase inducer phosphatase 3 1 S(0.196)PS(0.804)MPENLNRPR;SPS(1)MPENLNRPR;S(0.009)PS(0.991)MPENLNRPR 145.83 0.00055584 127530500.0 316152.0 270636.0 301053.0 239390.4 282669.0 255878.0 225046.8 244755.0 303984.0 228625.0 True False 311643.61450482387 270009.3589698267 276301.5844381865 256995.96859896436 266042.96516863647 244934.69442075118 236698.62214155047 256127.21082205672 269746.1208265689 268142.52662633697 1.1622312149654155 1.006962089777319 1.030428063442616 0.9584304728995651 0.992169979584677 0.9134496400195167 0.8827343619067022 0.955190562439117 1.0059803799882387 1.0 18.0326405191488 -1.5228787452809418 0.7017189276501256 0.9506800295625001 26.92513550710598 0.6841201833299226 0.04033896517008252 166.63400101674387 0.8788822376472821 0.016436588743520015 6792.674702370755 0.02999999999995826 1.5228787452809418 25.974455477543483 SPS(ph)MPSLNQTWPELNQSSEDTAIVHPVPIR ddPTM_PC-9_Lapatinib_30min_R1 2 SPSMPSLNQTWPELNQSSEDTAIVHPVPIR 30 0 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2 H0YDT0 REPS1 RalBP1-associated Eps domain-containing protein 1 1 S(0.222)PS(0.746)MPS(0.016)LNQT(0.016)WPELNQSSEDTAIVHPVPIR;S(0.45)PS(0.534)MPS(0.007)LNQT(0.009)WPELNQSSEDTAIVHPVPIR 93.649 2.0617e-10 7300600.0 3095.0 4219.1 4533.5 3785.3 7447.2 6089.0 6076.5 5685.0 6129.2 4444.4 True False 3050.8647324465132 4209.3309331707305 4160.773129816073 4063.6835893906305 7009.17033775854 5828.58766415227 6391.111437457149 5949.145854112852 5438.864952662667 5212.60861820925 0.5852855942011264 0.8075286754632294 0.7982132238513379 0.7795873212492742 1.3446569368882493 1.1181709756207698 1.2260869567553996 1.1412991632118035 1.043405586535508 1.0 12.347789825822586 -6.182948562020498 7.321837375693087 1.1548780551046878 0.7484486202151273 0.7761287120254743 0.1059713435638722 0.12661569284392074 10.368570020821476 0.03064199931324411 0.0396478363602788 6.562229849637926e-07 6.182948562020498 -0.4064294348895605 SPS(ph)PAHLPDDPK ddPTM_PC-9_AZD4547_30min_R2 1 SPSPAHLPDDPK 12 0 Q92615;H0Y4V9;A0A087X183;H0Y641 Q92615 LARP4B La-related protein 4B 1 S(0.306)PS(0.694)PAHLPDDPK 129.37 0.00017741 63122000.0 41478.0 43536.0 71020.0 75701.0 61546.0 61516.0 59320.0 68193.0 60057.0 58979.0 True False 54667.14120400435 57608.16060711821 70078.22839635628 58249.30401879114 53001.40026129068 57669.39479536752 64599.36508193297 57655.338769247544 63231.49041120446 56914.16316181046 0.9605191074949536 1.01219375647033 1.2312968249593617 1.0234588507114617 0.9312515078295088 1.0132696606890257 1.1350314489957976 1.0130226918268108 1.1109974547360637 1.0 15.796500093253398 SPS(ph)PAHLPDDPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSPAHLPDDPK 12 0 Q92615;H0Y4V9;A0A087X183;H0Y641 Q92615 LARP4B La-related protein 4B 1 S(0.13)PS(0.87)PAHLPDDPK 134.61 5.7918000000000003e-05 22839000.0 39211.0 50143.0 53061.0 60915.0 53911.0 48792.0 55022.0 44630.0 39657.0 38245.0 True False 45848.64784744854 55120.865656457725 54326.17547496307 57502.13003909462 43347.526553351665 46233.26162659296 49809.9178352166 43458.50978939381 40236.9086013269 45178.515752746585 1.014832981640421 1.2200680951566387 1.202478093177737 1.2727759883435044 0.959472125879133 1.0233461825000802 1.10251337400761 0.9619286748425725 0.8906204183761998 1.0 15.463349254279432 -6.27195838963485 24.896767082848395 0.9950715218529914 1.1823579772151214 0.5700162512886799 0.0798186835734802 513.8898411747582 1216290.6778842665 0.025495963053691232 0.029209191779556762 5.346155792137965e-07 6.27195838963485 0.18728645536212996 SPS(ph)PAHLPDDPK ddPTM_PC-9_Lapatinib_30min_R1 3 SPSPAHLPDDPK 12 0 Q92615;H0Y4V9;A0A087X183;H0Y641 Q92615 LARP4B La-related protein 4B 1 S(0.221)PS(0.779)PAHLPDDPK;S(0.085)PS(0.915)PAHLPDDPK;S(0.007)PS(0.993)PAHLPDDPK 105.66 0.0010052 221870000.0 413421.0 492884.0 572100.0 500715.0 590639.0 533857.0 499194.0 543674.0 529099.0 436809.0 True False 407525.5407278736 491742.7573807032 525064.1463698632 537539.2514362757 555898.7752609518 511025.18059144996 525039.822744999 568935.0788195167 469506.29896052723 512310.85363859346 0.795465366063394 0.9598523121034638 1.0248936610276589 1.0492443164506513 1.0850810036773244 0.9974904434719424 1.024846182773604 1.1105270848328903 0.9164480815230542 1.0 18.966659930985692 -4.738518656054575 1.959007466817275 1.032321143581574 0.7062702962290301 0.6595490463862013 0.04999584898068654 0.4945608849381823 1.8744558777234823 0.012817268337628609 0.30618014867873766 1.8259183111376972e-05 4.738518656054575 -0.32605084735254386 SPS(ph)PAHLPDDPKVAEK ddPTM_PC-9_AZD4547_30min_R2 2 SPSPAHLPDDPKVAEK 16 1 Q92615;H0Y4V9;A0A087X183;H0Y641 Q92615 LARP4B La-related protein 4B 1 S(0.197)PS(0.803)PAHLPDDPKVAEK;S(0.104)PS(0.896)PAHLPDDPKVAEK 106.67 0.00046887 26769000.0 125566.0 55345.0 146810.0 364530.0 314050.0 165645.0 97845.0 137899.0 113396.0 214790.0 True False 165493.3760649504 73234.18891953697 144863.2034760502 280493.24043235794 270449.5783975946 155287.19196434494 106553.01544911906 116589.8781537762 119389.88105747775 207270.26747698733 0.7984424301634323 0.35332703436428947 0.6989097145452083 1.3532729216142898 1.3048160823530657 0.7492014839107884 0.5140776665468885 0.5625017016332111 0.5760106478886717 1.0 17.66115365388483 -10.534222567450714 4.407502543973117 1.0000092200171107 0.7725819310012906 0.04826758898617012 0.3086245810008035 494682720.59117395 1042605081.7521247 73502.65751659346 0.08746906227589847 2.922654190716254e-11 10.534222567450714 -0.2274272890158201 SPS(ph)PAHLPDDPKVAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSPAHLPDDPKVAEK 16 1 Q92615;H0Y4V9;A0A087X183;H0Y641 Q92615 LARP4B La-related protein 4B 1 S(0.157)PS(0.843)PAHLPDDPKVAEK 82.865 0.0028320999999999997 8054600.0 29681.0 8766.6 21433.0 50163.0 54651.0 83824.0 42363.0 83548.0 67868.0 44497.0 True False 34705.40707352834 9636.890111558987 21944.044005105137 47352.5297406403 43942.52886548609 79428.12187628151 38350.06995843992 81354.95352642337 68860.44110635838 52563.953861941816 0.6602510755694179 0.1833364768729173 0.4174732377008916 0.9008555533134128 0.8359821824077441 1.5110758616997857 0.7295887607535312 1.5477327626475843 1.310031610012043 1.0 15.681786178848862 -6.087453839258571 1.41757935567208 1.2176786210904047 0.37904203389625507 0.6057808907060351 0.2669163347841852 0.263474458703588 1.0680258902429771 0.093625836717456 0.15323727602418297 8.176099362966109e-07 6.087453839258571 -0.8386365871941497 SPS(ph)PAHLPDDPKVAEK ddPTM_PC-9_Lapatinib_30min_R1 2 SPSPAHLPDDPKVAEK 16 1 Q92615;H0Y4V9;A0A087X183;H0Y641 Q92615 LARP4B La-related protein 4B 1 S(0.14)PS(0.86)PAHLPDDPKVAEK;S(0.122)PS(0.878)PAHLPDDPKVAEK 81.60600000000001 0.0033375 12788100.0 276400.0 56762.0 107752.0 80695.0 68533.0 63537.0 38861.0 37530.0 98261.0 37959.0 True False 272458.4853144473 56630.57107644687 98893.04649474856 86629.57949062865 64502.02368106219 60819.67062198109 40873.032431666674 39273.78081000094 87193.81144579808 44520.16257281183 6.119889721176263 1.2720207610165104 2.2213091951991633 1.9458504750279766 1.448827226890073 1.3661151960645188 0.9180791369487847 0.8821571741965107 1.9585241024938838 1.0 15.44217124048092 -4.760012457899733 24.999682408453612 1.4631556275588962 6.119895393411822 0.9098225241313357 0.441420237413504 10.474092906676708 183441.58987175656 0.11738596086104232 0.7162924976554533 1.7377509799972602e-05 4.760012457899733 4.656739765852926 SPS(ph)PASGRR ddPTM_PC-9_AZD4547_30min_R2 2 SPSPASGRR 9 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.007)PS(0.993)PASGRR;S(0.2)PS(0.8)PASGRR 90.913 0.0037619999999999997 3666600.0 7316.5 2411.0 6145.2 7982.4 6992.5 5325.200000000001 4440.4 4325.5 5196.0 8819.7 True False 9642.994807346018 3190.308600325295 6063.71063279765 6142.181006850614 6021.712074335861 4992.214402176527 4835.586997805381 3657.0933651017003 5470.649952155758 8510.924987507746 1.133013723126442 0.37484863337510316 0.7124619993359014 0.7216819577033106 0.7075273349459045 0.5865654331936954 0.568162333107507 0.42969399571369116 0.6427797166800936 1.0 13.05510022061219 -10.587556406988515 4.420891365581503 1.0000257803098462 0.6391513843636558 0.21814561424020773 0.19552679007311882 120166305.6850394 148846338.78486565 39757.1332660686 0.046316721896294204 2.5848990861774338e-11 10.587556406988515 -0.3608743959461904 SPS(ph)PASGRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSPASGRR 9 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.222)PS(0.778)PASGRR 65.695 0.023125 2149700.0 2307.4 1362.3 2769.9 2068.3 4873.8 4559.1 2728.9 3491.4 4262.6 4534.5 True False 2697.997246772661 1497.5401408729495 2835.944920904246 1952.419856519074 3918.8138768660447 4320.0127701631445 2470.3988364749134 3399.7544494440835 4324.932460953074 5356.568954917751 0.5036801111830527 0.2795707762705248 0.5294331025647725 0.3644907538670998 0.7315902977909517 0.8064887816289629 0.4611905227518621 0.6346888237708285 0.8074072223008435 1.0 12.387093491187661 -7.478681760911537 0.12377963675032844 1.301778640293922 8.410979263592324e-21 0.6148139225956013 0.13230334793028523 5.932407370743924 0.5757456343048506 2.382641424115994 3.069273051270139 3.321377498389967e-08 7.478681760911537 -1.301778640293922 SPS(ph)PASGRR ddPTM_PC-9_Lapatinib_30min_R1 3 SPSPASGRR 9 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.217)PS(0.783)PASGRR;S(0.112)PS(0.888)PASGRR;S(0.035)PS(0.964)PAS(0.001)GRR 79.23 0.0093737 5432100.0 12261.4 11188.8 8583.65 10632.099999999999 8822.0 7230.1 8916.6 7318.5 12490.699999999999 9299.4 True False 12086.550187534618 11162.893021037818 7877.935430847187 11414.020101645872 8303.107304719333 6920.885477186285 9378.257918741128 7658.544227497781 11083.865833097885 10906.788899328398 1.1081676100175428 1.0234811660951089 0.7222964984068118 1.0465060071299912 0.7612788127980188 0.6345484029320902 0.8598550870750427 0.7021813934593863 1.0162354782332306 1.0 13.412938795518722 -5.092027968452812 4.995815487330543 0.8302747720647375 1.090487518907497 0.3073281042129691 0.13523099399873756 0.2231995839503738 8.884986617453704 0.03374164768079535 0.09847513505598185 8.090437952885585e-06 5.092027968452812 0.2602127468427594 SPS(ph)PAVPLR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSPAVPLR 9 0 Q6P4R8-3;Q6P4R8;Q6P4R8-2;E9PQ59 Q6P4R8-3 NFRKB Nuclear factor related to kappa-B-binding protein 1 S(0.047)PS(0.953)PAVPLR 121.5 0.0016128 11097000.0 53656.0 48320.0 48668.0 47754.0 46657.0 48354.0 50855.0 49705.0 51391.0 34430.0 True False 52890.8556006947 48208.11800877198 44666.70490391278 51265.98846267408 43912.726991191295 46286.01213867936 53488.02306457391 52014.475757023625 45602.80440877881 40381.179624908764 1.309789760774335 1.19382639280392 1.106126797652056 1.269551532146206 1.0874552798874684 1.1462273407715968 1.3245780227673267 1.2880870801738284 1.1293083766341767 1.0 15.301395435195271 -4.768838262027593 5.2915615386137365 1.182533482024288 1.3160106124068984 0.15090249676766143 0.0955269351038725 0.31619504465747383 25.85438470794501 0.02360638707619931 0.15390849656219485 1.7027925365656268e-05 4.768838262027593 0.13347713038261033 SPS(ph)PEPIYNSEGK ddPTM_PC-9_AZD4547_30min_R2 4 SPSPEPIYNSEGK 13 0 Q15637-6;Q15637-4;Q15637-7;Q15637-3;Q15637-2;Q15637;Q15637-5 Q15637-6;Q15637-5 SF1 Splicing factor 1 1 S(0.109)PS(0.89)PEPIYNSEGK;S(0.018)PS(0.982)PEPIYNSEGK;S(0.023)PS(0.977)PEPIYNSEGK;S(0.186)PS(0.81)PEPIYNS(0.004)EGK 164.7 0.00032434 60879000.0 102537.0 139215.0 146577.0 132022.0 118213.0 163372.0 169926.0 170106.0 154049.0 138885.0 True False 135141.63309790718 184213.52625229603 144633.29320828966 101586.36761956694 101801.165454911 153156.32301366786 185049.0848097192 143820.02634700955 162191.71564273318 134022.67842330382 1.0083489950191056 1.374495185586927 1.0791702934892313 0.7579789391964811 0.7595816368732551 1.1427642307664632 1.3807296420778212 1.0731021647900612 1.2101811242009273 1.0 17.032117619004296 -8.098019863699115 18.10687352906187 1.1172719235599273 1.0740638490296863 0.0034080533366969146 0.20360832975601625 50.308742464785624 9257.521727314703 0.15231142947310816 0.057567671844512724 7.979581895353763e-09 8.098019863699115 -0.043208074530241 SPS(ph)PEPIYNSEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPSPEPIYNSEGK 13 0 Q15637-6;Q15637-4;Q15637-7;Q15637-3;Q15637-2;Q15637;Q15637-5 Q15637-6;Q15637-5 SF1 Splicing factor 1 1 S(0.044)PS(0.952)PEPIY(0.003)NS(0.001)EGK;S(0.003)PS(0.997)PEPIYNSEGK;S(0.001)PS(0.999)PEPIYNSEGK 168.0 0.0002669 39678000.0 60027.0 106626.0 94960.0 66135.0 85865.0 63616.0 80702.0 58725.0 56997.0 55102.0 True False 70188.38551270793 117211.12461331506 97224.20653780524 62429.67036256292 69040.36963706005 60279.86497043246 73057.32232811686 57183.53097428077 57830.47329726985 65091.55641280797 1.0783024616522623 1.8007116602031594 1.4936531233208394 0.959105509271226 1.0606655216416838 0.9260781012538715 1.1223778682566803 0.8785091972855154 0.8884481564784128 1.0 15.99018279066048 -5.760219749559287 24.99298805396396 0.9788826181460335 1.4918714620574158 0.6045679018789325 0.17764648141984565 19.304646433425795 395576.4909865772 0.046943873271665736 0.07586077973385397 1.7369217377544868e-06 5.760219749559287 0.5129888439113823 SPS(ph)PEPIYNSEGK ddPTM_PC-9_Lapatinib_30min_R1 2 SPSPEPIYNSEGK 13 0 Q15637-6;Q15637-4;Q15637-7;Q15637-3;Q15637-2;Q15637;Q15637-5 Q15637-6;Q15637-5 SF1 Splicing factor 1 1 S(0.124)PS(0.875)PEPIYNSEGK;S(0.151)PS(0.849)PEPIYNSEGK 162.88 0.0003366 28818000.0 37029.0 76868.0 61540.0 58532.0 76441.0 75616.0 67129.0 76940.0 60125.0 59384.0 True False 36500.95966971307 76690.016868756 56480.418751269666 62836.63853702811 71944.89066878839 72382.07994950535 70604.61115528042 80514.91328327949 53353.089355681455 69648.44527579381 0.5240742923288039 1.1011016335695505 0.8109358152593154 0.9021972893753433 1.0329719548498335 1.0392490408491803 1.0137284597768175 1.1560188165644854 0.766034175557171 1.0 16.087803528241928 -4.7521833327737815 24.999897046179832 0.9819316548113945 0.5240733995821278 0.5829926806917889 0.11573446241760119 259.5552364078185 700989.3638028138 0.02815713927149926 0.34398419856783596 1.7693618834355837e-05 4.7521833327737815 -0.4578582552292667 SPS(ph)PFTHTHLAQGYR ddPTM_PC-9_AZD4547_30min_R2 2 SPSPFTHTHLAQGYR 15 0 P38398-8;P38398-4;P38398;P38398-7;Q5YLB2 P38398-8 BRCA1 Breast cancer type 1 susceptibility protein 1 S(0.022)PS(0.958)PFT(0.019)HTHLAQGYR;S(0.239)PS(0.754)PFT(0.007)HTHLAQGYR 115.58 8.938e-05 6783500.0 62365.0 52146.0 76692.0 96271.0 77047.0 77277.0 62034.0 77200.0 64424.0 77659.0 True False 82195.77272741542 69001.17472939144 75675.01397033744 74077.20832212304 66350.35397802725 72444.85697382182 67554.90582421832 65270.513879517166 67829.32111579727 74940.18204755985 1.0968184288003318 0.9207500281437895 1.009805579632983 0.9884844992117963 0.885377539327551 0.9667024417934507 0.9014510504037133 0.8709681788348745 0.90511284150271 1.0 16.19345186187077 -1.5228787454336143 0.5219324386630871 0.9181894778872662 6.344953888618286 0.43285627831483675 0.05042615135221863 113.36216635987778 1.1314761567103275 0.02616069979827052 681.5871525087349 0.029999999989412014 1.5228787454336143 5.426764410731019 SPS(ph)PFTHTHLAQGYR ddPTM_PC-9_Lapatinib_30min_R1 2 SPSPFTHTHLAQGYR 15 0 P38398-8;P38398-4;P38398;P38398-7;Q5YLB2 P38398-8 BRCA1 Breast cancer type 1 susceptibility protein 1 S(0.028)PS(0.972)PFTHTHLAQGYR;S(0.17)PS(0.794)PFT(0.036)HTHLAQGYR 145.94 6.4756e-05 7946300.0 60302.0 51181.0 56614.0 51493.0 49314.0 60348.0 47275.0 41303.0 53997.0 41635.0 True False 59442.08242196757 51062.49353905126 51959.41545635982 55279.96699561243 46413.44747505433 57767.05671805896 49722.66818164849 43222.08816401461 47915.28924638223 48831.55427484971 1.2172883559551724 1.0456864275022797 1.0640540983787832 1.1320542181489381 0.9504806505608033 1.182986238629955 1.0182487311745827 0.8851262018148742 0.9812362100270194 1.0 15.575526078248384 -7.521810716439751 24.43217605804576 0.9502461772430901 1.0904650167174577 0.4243767744595722 0.07506578128245324 28.513506450799355 652349.0628351895 0.033074969405216655 0.019427278639037277 3.00738676100097e-08 7.521810716439751 0.14021883947436753 SPS(ph)PGNSPSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSPGNSPSGR 11 0 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 S(0.378)PS(0.586)PGNS(0.027)PS(0.009)GR;S(0.118)PS(0.824)PGNS(0.055)PS(0.003)GR 69.846 0.033698 6868700.0 9707.6 15347.1 17163.0 16233.1 18273.3 12135.8 16709.0 12429.2 13901.8 9858.7 True False 11350.9049461603 16870.658662549555 17572.231011039974 15323.61203542029 14692.778040981626 11499.377284145083 15126.202557315877 12102.946669825978 14105.087525378281 11646.004268573739 0.9746608952213979 1.448622057272839 1.5088635214103359 1.3157827939983178 1.261615374865479 0.987409674507477 1.2988319606007108 1.0392359809179599 1.2111525292361671 1.0 13.507547432221445 -6.562225438621314 7.4554059331540286 1.1213700690574735 1.330224921064374 0.27271677996381816 0.15861057062129635 0.2814333167689893 43.36936345953441 0.05177956707625868 0.05202510788262103 2.740151413083305e-07 6.562225438621314 0.20885485200690046 SPS(ph)PHSCHR ddPTM_PC-9_AZD4547_30min_R2 2 SPSPHSCHR 9 0 P21580;A0A087WU80;D3TTY5 P21580 TNFAIP3 Tumor necrosis factor alpha-induced protein 3;A20p50;A20p37 1 S(0.069)PS(0.93)PHS(0.001)CHR;S(0.03)PS(0.941)PHS(0.028)CHR 73.95100000000001 0.015988 2689700.0 1765.63 1599.1599999999999 7529.2 15848.4 9684.2 9253.2 3909.19 10032.8 11950.4 16530.8 True False 2327.063612614548 2116.0571967217747 7429.357888508114 12194.796235339149 8339.715991459903 8674.595941226593 4257.10033689551 8482.461290808536 12582.073746774868 15952.061723583916 0.14587854867525749 0.13265101611244046 0.465730262159428 0.7644652112466481 0.5227986285390473 0.5437915230983503 0.26686834659131925 0.5317470204035043 0.7887427948058415 1.0 13.96145527665347 -9.307555789083406 0.12689268148708815 1.4917017617880157 4.781577610716992e-12 0.5741380520782207 0.17510407862718658 16.304203102971776 0.784567375952224 5.911605426701751 2.807006997564743 4.925430676405006e-10 9.307555789083406 -1.4917017617832342 SPS(ph)PHSCHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSPHSCHR 9 0 P21580;A0A087WU80;D3TTY5 P21580 TNFAIP3 Tumor necrosis factor alpha-induced protein 3;A20p50;A20p37 1 S(0.042)PS(0.958)PHSCHR;S(0.003)PS(0.997)PHSCHR 108.98 0.0013595999999999999 1530700.0 1473.93 2514.52 10973.3 7088.6 22028.4 22571.9 6550.799999999999 12034.099999999999 22419.8 11769.5 True False 1723.4372375555295 2764.144927716252 11234.945088471986 6691.448723551279 17712.093152192523 21388.189828441024 5930.260800315093 11718.217626182919 22747.64716090549 13903.217182689254 0.12395959977532126 0.19881333157608003 0.8080823985444532 0.4812877937260974 1.2739564461559056 1.5383626355971214 0.4265387444064958 0.8428421617964184 1.6361426899975597 1.0 13.763131138502699 -5.454962537216736 1.062115870342522 1.0808751230845408 0.014972593113308435 0.4966375691155547 0.35893448438646625 0.6884570954200812 1.2460979502335394 0.13213129006897664 0.6463385880254662 3.5078213155136247e-06 5.454962537216736 -1.0659025299712324 SPS(ph)PHSCHR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSPHSCHR 9 0 P21580;A0A087WU80;D3TTY5 P21580 TNFAIP3 Tumor necrosis factor alpha-induced protein 3;A20p50;A20p37 1 S(0.342)PS(0.656)PHS(0.002)CHR 63.091 0.033402 1210600.0 684.98 1215.1 3061.5 1191.4 4745.9 2047.1 2110.1 4834.7 6617.5 1029.4 True False 675.2120595900523 1212.2865106055212 2809.7952877317534 1279.0195303938922 4466.7554927983965 1959.5503050231732 2219.3506532014057 5059.337811940089 5872.1674646357105 1207.3304184107194 0.5592603725489448 1.0041050006851693 2.3272794629248663 1.0593782040856234 3.699695977740917 1.6230439282749503 1.83822971686812 4.190516311682095 4.863761713521302 1.0 10.237604847057165 -5.499801064545093 0.5425584376294673 3.150022066614938 3.895152978832e-10 0.290694826018973 1.2101751698089473 2.6773402329219493 1.0321751150583534 0.8104237214322506 4.883633717546019 3.163726523267506e-06 5.499801064545093 -3.150022066225423 SPS(ph)PISISSSETSSIMQK ddPTM_PC-9_AZD4547_30min_R2 2 SPSPISISSSETSSIMQK 18 0 Q5VT06 Q5VT06 CEP350 Centrosome-associated protein 350 1 S(0.418)PS(0.571)PIS(0.011)ISSSETSSIMQK;S(0.166)PS(0.834)PISISSSETSSIMQK 128.45 3.7448000000000005e-05 12788200.0 56105.0 41099.0 73455.0 102100.0 84504.0 76357.0 62427.0 80444.0 64716.0 75560.0 True False 73945.22294350424 54383.44801525064 72480.93870535567 78562.4224292754 72772.07824521673 71582.38471925817 67982.88206287636 68013.228219221 68136.75563966755 72914.66739867408 1.0141337207121224 0.74585059433789 0.9940515576797887 1.0774570498925984 0.9980444379910874 0.9817281936961817 0.9323622322950156 0.9327784195647004 0.9344725563529978 1.0 16.153921433537498 SPS(ph)PISISSSETSSIMQK ddPTM_PC-9_Lapatinib_30min_R1 1 SPSPISISSSETSSIMQK 18 0 Q5VT06 Q5VT06 CEP350 Centrosome-associated protein 350 1 S(0.012)PS(0.886)PIS(0.101)ISSSETSSIMQK 87.669 0.0014257 5654600.0 47213.0 46277.0 44766.0 47229.0 47088.0 48017.0 39763.0 40221.0 51838.0 36349.0 True False 46539.73396219617 46169.84844975039 41085.512281757205 50702.37821132545 44318.37641856993 45963.42484309401 41821.73357814676 42089.81449397944 45999.458561660154 42631.87621800198 1.0916651597553673 1.0829888934199534 0.9637275186215756 1.1893067514095375 1.039559605398174 1.078146891965436 0.9809967866365422 0.9872850605671057 1.078992121445412 1.0 15.379644928889375 -7.246385611134521 24.30801569239733 1.0107589141732305 1.0732621517570269 0.21920337585668526 0.05767626866416226 878.4132124269271 1418415.3871799565 0.021642260305648253 0.016680718135429592 5.670409048144854e-08 7.246385611134521 0.06250323758379639 SPS(ph)PISNQPSPR ddPTM_PC-9_AZD4547_30min_R2 3 SPSPISNQPSPR 12 0 F6SS63;Q8N5C8-2;Q8N5C8 F6SS63 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 1 S(0.139)PS(0.861)PISNQPSPR;S(0.008)PS(0.983)PIS(0.008)NQPSPR;S(0.018)PS(0.962)PIS(0.006)NQPS(0.014)PR 108.66 0.0014053 28649800.0 13919.5 12549.0 20171.0 31125.9 21578.7 20773.4 16528.5 27129.800000000003 19561.4 19462.8 True False 18345.611456413983 16605.21884092994 19903.519360502734 23950.30464536123 18582.86998047497 19474.436014079078 17999.504480052754 22937.51279078398 20595.375668610395 18781.413296015256 0.9767961104559828 0.8841304208162531 1.0597455605071824 1.2752131199009729 0.9894287340142602 1.0368993912833415 0.9583679458175602 1.2212878993323948 1.0965828473078751 1.0 14.197018009017984 -5.354608866279414 5.927021301421088 1.0866810625944414 0.9315615782972577 0.274555954252631 0.09708738185608326 0.27177078556489453 13.874268869615289 0.026013004928133958 0.055302553951754076 4.419683130800156e-06 5.354608866279414 -0.1551194842971837 SPS(ph)PISNQPSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPSPISNQPSPR 12 0 F6SS63;Q8N5C8-2;Q8N5C8 F6SS63 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 1 S(0.011)PS(0.987)PIS(0.002)NQPSPR;S(0.012)PS(0.924)PIS(0.063)NQPSPR;S(0.246)PS(0.671)PIS(0.08)NQPS(0.003)PR;S(0.097)PS(0.864)PIS(0.039)NQPSPR 133.04 6.9446e-05 42202400.0 30026.999999999996 25171.3 33280.700000000004 39793.5 45232.1 35585.7 34819.100000000006 37496.4 30414.2 24340.800000000003 True False 35109.97803971685 27670.140312673633 34074.23810575761 37563.99920726769 36369.19470634669 33719.523246955425 31520.78277954618 36512.159230719815 30858.950136986597 28753.594358333223 1.2210639686353317 0.9623193527683057 1.1850427352183324 1.306410556507732 1.2648573341164338 1.1727063693928408 1.096238000255818 1.2698293916126713 1.073220612088214 1.0 14.811454691739227 -10.604775157027744 7.690278941553089 0.9999999848707747 1.1738961382840933 0.21377390595532209 0.09915581163900859 2.6492990558316567e-08 3.060391383663694e-09 0.09871404135062929 0.023941669578286785 2.4844190059955954e-11 10.604775157027744 0.17389615341331865 SPS(ph)PISNQPSPR ddPTM_PC-9_Lapatinib_30min_R1 3 SPSPISNQPSPR 12 0 F6SS63;Q8N5C8-2;Q8N5C8 F6SS63 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 1 S(0.016)PS(0.903)PIS(0.075)NQPS(0.006)PR;S(0.078)PS(0.902)PIS(0.02)NQPSPR;S(0.002)PS(0.994)PIS(0.004)NQPSPR 121.56 0.00044126 32026900.0 29448.0 21991.8 26749.999999999996 25694.6 22603.0 22702.699999999997 20555.1 22238.0 22899.6 16622.9 True False 29028.066119898194 21940.879338272156 24550.718257986086 27584.266598672883 21273.535979207794 21731.75844357852 21619.342501123258 23271.258663810317 20320.405904521624 19496.14611637804 1.4889130367930878 1.1253957170458617 1.2592600666529614 1.4148573997145155 1.0911662157341255 1.1146694487133753 1.1089033890119233 1.1936337840769944 1.0422780883577372 1.0 14.250901348227652 -1.5228787999408806 0.15284188813360966 0.9661936318661397 2.471702840072781 0.5237531796513708 0.10430971138362866 59.920261152186264 0.5998005935187247 0.35821931109440996 20.079549150167956 0.02999999622418369 1.5228787999408806 1.5055092082066415 SPS(ph)PLVSLQAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSPLVSLQAVK 12 0 Q9UPZ3;Q9UPZ3-2 Q9UPZ3 HPS5 Hermansky-Pudlak syndrome 5 protein 1 S(0.282)PS(0.715)PLVS(0.002)LQAVK;S(0.145)PS(0.855)PLVSLQAVK 139.77 7.3423e-05 53997000.0 106592.0 95644.0 134976.0 141426.0 170028.0 152465.0 151650.0 135094.0 131412.0 112864.0 True False 124635.9203120356 105138.9042308245 138194.33973933046 133502.35972927808 136712.23395621087 144469.4670007072 137284.61414907876 131547.92564392503 133333.65189292125 133325.34976906763 0.9348253766288034 0.788588999863381 1.0365196114519586 1.001327654197173 1.025403152461326 1.0835858840868766 1.0296962609651423 0.9866685208160243 1.0000622696574057 1.0 17.02459158726505 -5.274759545543423 24.999617867372226 1.0220168463677817 0.8617071881550596 0.6982175680882461 0.04172331945384394 347.2913084688438 651805.1085364512 0.010667426812812311 0.022411779227598464 5.311784587330142e-06 5.274759545543423 -0.16030965821272203 SPS(ph)PLVSLQAVK ddPTM_PC-9_Lapatinib_30min_R1 2 SPSPLVSLQAVK 12 0 Q9UPZ3;Q9UPZ3-2 Q9UPZ3 HPS5 Hermansky-Pudlak syndrome 5 protein 1 S(0.089)PS(0.911)PLVSLQAVK;S(0.005)PS(0.995)PLVSLQAVK 142.1 8.0438e-05 47385000.0 155610.0 109001.0 120992.0 113351.0 106088.0 97355.0 96344.0 86922.0 108892.0 73174.0 True False 153390.97286462103 108748.61488150165 111044.50480262647 121687.21066785116 99848.11241703288 93191.35359558955 101332.22090518745 90960.71344436193 96627.4362764052 85822.02840177379 1.787314699048184 1.2671410464967992 1.2938928020061966 1.4179018246711133 1.163432212876586 1.085867525285192 1.1807250748118312 1.059876061406187 1.1259048297489096 1.0 16.389060379104606 -1.5228787452803376 0.3956957877609594 1.0785987314405072 10.58676430579365 0.7774632061811731 0.1023798328962284 35.1325842034294 0.4691552055965341 0.07579779159498272 259.5178592789782 0.029999999999999995 1.5228787452803376 9.508165574353143 SPS(ph)PPDGSPAATPEIR ddPTM_PC-9_AZD4547_30min_R2 3 SPSPPDGSPAATPEIR 16 0 O00499-6;O00499-11;O00499-2;O00499;O00499-7;O00499-8;O00499-4;O00499-3;O00499-5;O00499-9;O00499-10 O00499-6;O00499-9 BIN1 Myc box-dependent-interacting protein 1 1 S(0.03)PS(0.948)PPDGS(0.021)PAAT(0.001)PEIR;S(0.017)PS(0.983)PPDGSPAATPEIR;S(0.017)PS(0.983)PPDGSPAATPEIR 262.24 1.0312999999999999e-58 470437000.0 191373.6 222187.4 301663.0 384242.0 318641.0 300608.1 270468.0 339478.0 224020.0 271811.0 True False 252226.4239818377 294005.1319385797 297662.75151689746 295660.9433797219 274403.19729402266 281811.02798597596 294539.1280340562 287019.4755283769 235861.23985410598 262294.979622829 0.9616136166408158 1.1208950028755746 1.1348396829589573 1.1272077864581014 1.0461625978835158 1.074404963416419 1.1229308637839472 1.0942621774198684 0.8992213278091185 1.0 18.000830668838937 -8.249622927924404 24.73056278060995 0.9496106663272353 1.0891130383278533 0.5018762015261284 0.05396084897702202 434.15744825569107 908650.0144382574 0.03643635990456281 0.013532767593702727 5.628297847458467e-09 8.249622927924404 0.139502372000618 SPS(ph)PPDGSPAATPEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPSPPDGSPAATPEIR 16 0 O00499-6;O00499-11;O00499-2;O00499;O00499-7;O00499-8;O00499-4;O00499-3;O00499-5;O00499-9;O00499-10 O00499-6;O00499-9 BIN1 Myc box-dependent-interacting protein 1 1 S(0.403)PS(0.596)PPDGSPAATPEIR;S(0.024)PS(0.976)PPDGSPAATPEIR;S(0.009)PS(0.528)PPDGS(0.463)PAATPEIR 213.0 7.157799999999999e-22 268699000.0 128687.0 137355.0 142471.0 141548.0 163030.0 155237.0 149967.0 118418.0 123803.0 102021.0 True False 150471.1674158941 150990.69665242892 145868.04896427653 133617.52446480785 131085.4418206471 147096.0984408799 135761.04009294338 115309.652974242 125613.3846627349 120516.59970220836 1.2485513845204914 1.252862236617369 1.2103564930035413 1.1087063922726939 1.087696152601002 1.220546371241376 1.1264924535574636 0.9567947756505534 1.0422911447312693 1.0 16.878872348350022 -6.095824792097212 0.29257955601246194 0.9724233704229205 1.3533634665583645 0.6811153607747518 0.05659530076372183 2.3861502517167605 0.30962061282836745 0.08287965584467318 0.31275155825675566 8.02001550502748e-07 6.095824792097212 0.380940096135444 SPS(ph)PPDGSPAATPEIR ddPTM_PC-9_Lapatinib_30min_R1 2 SPSPPDGSPAATPEIR 16 0 O00499-6;O00499-11;O00499-2;O00499;O00499-7;O00499-8;O00499-4;O00499-3;O00499-5;O00499-9;O00499-10 O00499-6;O00499-9 BIN1 Myc box-dependent-interacting protein 1 1 S(0.024)PS(0.976)PPDGSPAATPEIR;S(0.017)PS(0.983)PPDGSPAATPEIR 273.84 3.2244e-82 416620000.0 278480.0 268820.0 323700.0 243460.0 295970.0 298680.0 261160.0 272880.0 253330.0 232660.0 True False 274508.8241330226 268197.5638062512 297086.6355181345 261364.86055875118 278561.62649940845 285906.15265708655 274681.5869343063 285559.00099741726 224797.3077168363 272874.97100003687 1.0059875522001813 0.982858789955547 1.0887280516397906 0.9578191052147318 1.0208397841639012 1.047755137121198 1.006620672931814 1.046482936675708 0.8238106517904346 1.0 18.057880546329542 -8.239105793006107 24.99685636805207 0.9119052893190807 1.0191965909665222 0.40446996285235637 0.05228678054517526 619.3970245378957 693262.2228364652 0.032499746354279165 0.012263436893159799 5.766259816932329e-09 8.239105793006107 0.1072913016474415 SPS(ph)PPLPLSCSNSTR ddPTM_PC-9_AZD4547_30min_R2 1 SPSPPLPLSCSNSTR 15 0 Q96HJ3-2;Q96HJ3 Q96HJ3-2 CCDC34 Coiled-coil domain-containing protein 34 1 S(0.365)PS(0.635)PPLPLSCSNSTR 111.07 0.00046052 15266000.0 15049.0 15254.0 20891.0 28029.0 22052.0 22855.0 21195.0 18303.0 19017.0 20445.0 True False 19834.268961354486 20184.5571917719 20613.9716900631 21567.347093733177 18990.46044522766 21425.873237013548 23081.313939844404 15474.691911098458 20022.199796025034 19729.226772973678 1.0053241918494598 1.0230789794267032 1.0448443787113542 1.0931673776124602 0.9625547247113595 1.0859966020748488 1.1699046397227602 0.784353694605845 1.0148496961600486 1.0 14.268046794675493 -7.755140515776702 24.999950498380112 0.9247012728279697 1.052471319341343 0.3355783096897371 0.0782909810814305 156.40594232255222 620776.4076937849 0.03656427673839346 0.020446519781743073 1.7573549305983387e-08 7.755140515776702 0.12777004651337343 SPS(ph)PPLPLSCSNSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSPPLPLSCSNSTR 15 0 Q96HJ3-2;Q96HJ3 Q96HJ3-2 CCDC34 Coiled-coil domain-containing protein 34 1 S(0.437)PS(0.557)PPLPLS(0.002)CS(0.003)NS(0.001)T(0.001)R;S(0.014)PS(0.986)PPLPLSCSNSTR 130.95 1.0872e-05 21353000.0 22505.4 27313.0 26495.0 23089.4 32323.0 25997.0 26389.0 19131.1 20225.8 18722.0 True False 26315.11971808851 30024.454134671436 27126.74128284704 21795.7757748448 25989.54018259697 24633.671554897082 23889.242880184844 18628.928896075988 20521.56406154569 22116.15039672954 1.189859864670657 1.3575804828633897 1.2265580038223312 0.9855139969597911 1.1751385171643711 1.113831797713757 1.0801718405621579 0.8423224006846495 0.927899462312408 1.0 14.432812667162057 -6.469629465098162 0.5159627235673206 0.9199701660099334 1.30032037760123 0.5872159637102784 0.09415616185293472 0.8067245558915187 0.44581343019453656 0.084186108011978 0.14563317851370247 3.3913337731750063e-07 6.469629465098162 0.38035021159129656 SPS(ph)PPLPLSCSNSTR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSPPLPLSCSNSTR 15 0 Q96HJ3-2;Q96HJ3 Q96HJ3-2 CCDC34 Coiled-coil domain-containing protein 34 1 S(0.252)PS(0.744)PPLPLS(0.002)CS(0.001)NS(0.001)T(0.001)R 86.49799999999999 0.0054583 15425000.0 15064.0 16032.0 13589.0 9239.9 15168.0 11239.0 11453.0 11375.0 14366.0 12826.0 True False 14849.184597600737 15994.87888900314 12471.764875056928 9919.433069402812 14275.848061435361 10758.334169388632 12045.980300040606 11903.524026479103 12747.949799313428 15042.957010429265 0.9871187285389311 1.0632802365860587 0.8290766812941277 0.6594071273703488 0.9490054416520589 0.7151741616977229 0.8007721016346149 0.7913021368223284 0.8474364309141673 1.0 13.876800566575787 -5.295620193420173 7.46832074812438 0.8100699743969609 1.0251893459001922 0.4070041265339396 0.09598825431286953 0.1790449148805337 34.08023395150829 0.023446912631583647 0.05022264917850658 5.062672178573545e-06 5.295620193420173 0.21511937150323124 SPS(ph)PPLPT(ph)HIPPEPPRTPPFPAK ddPTM_PC-9_AZD4547_30min_R2 1 SPSPPLPTHIPPEPPRTPPFPAK 23 1 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 2 S(0.221)PS(0.716)PPLPT(0.669)HIPPEPPRT(0.394)PPFPAK 53.958 0.014740000000000001 4936800.0 18449.0 21770.0 28193.0 32172.0 29245.0 29521.0 25325.0 31193.0 26137.0 30304.0 True False 24315.39823696121 28806.726764446965 27819.14239902104 24755.24245244511 25184.836555445447 27675.04720323241 27578.875938974255 26372.83859383131 27518.548460256963 29243.066183819723 0.8314927745304285 0.9850788759075413 0.9513073021875338 0.8465337491231429 0.861224209429184 0.9463798026263436 0.9430911165612904 0.9018492940532851 0.9410281496228005 1.0 14.83580696773015 -6.80336373953874 24.981724003109594 0.9401241335564366 0.900546055205205 0.20603718409349703 0.049044099566324585 320.2267776296829 190813.39412319165 0.017943075833677487 0.015824461078413423 1.5726651408077336e-07 6.80336373953874 -0.039578078351231616 SPS(ph)PPLPTHIPPEPPR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSPPLPTHIPPEPPR 16 0 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 S(0.217)PS(0.783)PPLPTHIPPEPPR 104.84 0.0023054000000000004 0.0 12803.0 12904.0 14166.0 11241.0 13502.0 11032.0 12595.0 11583.0 13623.0 9347.2 True False 12620.426872217355 12874.121580819397 13001.32616234135 12067.700638876726 12707.838905953338 10560.187076848062 13247.107472191696 12121.188465820427 12088.634283450292 10962.851065638892 1.1511993364366537 1.1743406440292747 1.1859438830736007 1.1007812262177663 1.1591728127898955 0.9632701396397778 1.2083633530069928 1.1056602332044936 1.102690733557438 1.0 13.420335422679809 -9.519524516663864 0.017308134173096113 4.095213555922587e-07 2.126346460122246 0.3117277276031156 0.0627560267934398 1358.1559770250644 7.129783813710307 465.2147139289366 410.30041201220564 3.0232598975188925e-10 9.519524516663864 2.1263460506008904 SPS(ph)PPLPTHIPPEPPRT(ph)PPFPAK ddPTM_PC-9_AZD4547_30min_R2 1 SPSPPLPTHIPPEPPRTPPFPAK 23 1 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 2 S(0.359)PS(0.475)PPLPT(0.218)HIPPEPPRT(0.948)PPFPAK 54.732 0.040629000000000005 0.0 5493.6 6563.5 7597.5 12196.0 10818.0 8664.7 7666.3 11046.0 8581.7 8582.2 True False 7240.450526021469 8685.023018761947 7496.752185881688 9384.400626321663 9316.107432272489 8122.894939258423 8348.585848409017 9339.094511828309 9035.31114211222 8281.73979021838 0.8742668460283206 1.0486954720576813 0.9052146500347854 1.13314362247962 1.1248973848799027 0.980819869377257 1.008071499453483 1.1276730190024538 1.0909919136536852 1.0 13.015718159036263 -5.756332160829023 24.999998552654667 1.0682605717749332 0.9533226347714218 0.4139413888310134 0.06712108491090173 135.7054662537119 664273.4997225343 0.018596597957708513 0.03098238506054028 1.7525395967662711e-06 5.756332160829023 -0.1149379370035114 SPS(ph)PPTQHTGQPPGQPSAPSQLSAPR ddPTM_PC-9_AZD4547_30min_R2 1 SPSPPTQHTGQPPGQPSAPSQLSAPR 26 0 Q68EM7-6;Q68EM7-5;Q68EM7;Q68EM7-7;Q68EM7-3;Q68EM7-2;I3L460 Q68EM7-6 ARHGAP17 Rho GTPase-activating protein 17 1 S(0.152)PS(0.48)PPT(0.27)QHT(0.098)GQPPGQPSAPSQLSAPR 101.59 0.00026178 0.0 632.47 620.93 1179.9 1283.6 1108.2 869.13 972.61 706.64 614.17 1140.2 True False 833.5823038067563 821.6334795520471 1164.253755067035 987.6858514223097 954.345558924419 814.7831637053413 1059.170405804768 597.445024971787 646.6337723470944 1100.2819450498703 0.7576079090973125 0.7467481251042491 1.0581412885169765 0.8976661444513141 0.8673645543471709 0.7405221610433781 0.9626354504588014 0.5429926644344854 0.5876982488500124 1.0 10.103657543507465 -7.7558331304351285 24.99981224678328 0.6740090910988568 0.8616345787542578 0.16726631481194232 0.14822984387355315 186.84421283017707 833200.9183875134 0.07051842788789983 0.03925533623184739 1.7545545272368273e-08 7.7558331304351285 0.187625487655401 SPS(ph)PQGTK ddPTM_PC-9_Lapatinib_30min_R1 1 SPSPQGTK 8 0 Q9ULL5;Q9ULL5-2;A0A3Q5ADB5 Q9ULL5 PRR12 Proline-rich protein 12 1 S(0.006)PS(0.994)PQGT(0.001)K 79.07 0.021233000000000002 4577100.0 10079.0 23726.0 13188.0 19350.0 23038.0 11989.0 36356.0 28983.0 17548.0 19021.0 True False 9935.271611737775 23671.06390472108 12103.733547152176 20773.063549707746 21682.950134450686 11476.258417724019 38238.335788725766 30329.655987643408 15571.55945136795 22308.754506110647 0.4453530388268148 1.0610661342943766 0.5425553248092274 0.9311619590424801 0.9719480362972059 0.5144284686346129 1.714050678098224 1.3595405328135077 0.6980021877556053 1.0 14.44532234996628 -7.2413222641382475 24.99728019919998 1.2228601550511569 0.7684668437399584 0.3316519572782235 0.30960541463812863 939.9015518398428 1167911.6360709947 0.11615639057225412 0.08985483496589221 5.736906025049546e-08 7.2413222641382475 -0.4543933113111984 SPS(ph)PSLSSLLLPSSPGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSPSLSSLLLPSSPGPR 18 0 Q8TER5-4;Q8TER5-3;Q8TER5;Q8TER5-2 Q8TER5-4 ARHGEF40 Rho guanine nucleotide exchange factor 40 1 S(0.082)PS(0.916)PS(0.003)LSSLLLPSSPGPR 136.36 8.5697e-05 2023300.0 1460.8 1817.7 1724.1 3820.2 4598.0 2682.4 1634.1 2497.5 1221.2 2597.0 True False 1708.0845878848502 1998.1492432391988 1765.2090826856618 3606.1665792555045 3697.0549070191764 2541.7302219046774 1479.306218140515 2431.9432713199863 1239.0577397165803 3067.815542159313 0.5567755180882217 0.6513263968383123 0.5753960948523006 1.1754835092586002 1.2051099084063468 0.8285146831597492 0.4822018135742576 0.7927279974624024 0.40388925692854954 1.0 11.582996025517206 -10.883027367642093 4.160051938794032 1.0005302396922802 0.7566187040934549 0.08019943318462985 0.25819626140035157 0.001380531377066043 0.00021233643355385664 0.27180610565644864 0.0657810817033701 1.3090994257656014e-11 10.883027367642093 -0.24391153559882528 SPS(ph)PSPTPEAK ddPTM_PC-9_AZD4547_30min_R2 1 SPSPSPTPEAK 11 0 F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 F8VXC8 SMARCC2 SWI/SNF complex subunit SMARCC2 1 S(0.179)PS(0.49)PS(0.314)PT(0.017)PEAK 86.288 0.011000000000000001 3767500.0 13628.0 19405.0 21394.0 25240.0 20665.0 18888.0 15639.0 21910.0 18037.0 19976.0 True False 17961.420519990636 25677.286764542652 21110.301581408723 19421.30795411273 17796.021453864934 17706.930374128726 17030.840703242582 18524.312941712695 18990.398996734693 19276.64632022119 0.9317710260186243 1.332041182786406 1.0951231469793596 1.007504502157089 0.923190743775639 0.9185690332220375 0.8834960407701853 0.9609717703997455 0.9851505641214041 1.0 14.234566458189978 -5.826636128706975 2.797444717522346 0.9404550229115078 1.1466583355769053 0.3942051913573079 0.09586899462625821 0.22596631850974022 3.5872097115173682 0.026951327078440276 0.04554883564411173 1.490609453769349e-06 5.826636128706975 0.2062033126653975 SPS(ph)PTLGESLAPHK ddPTM_PC-9_AZD4547_30min_R2 2 SPSPTLGESLAPHK 14 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 S(0.079)PS(0.842)PT(0.079)LGESLAPHK;S(0.106)PS(0.458)PT(0.436)LGESLAPHK 145.81 0.00010421 13802200.0 21205.0 22854.0 55687.0 88398.0 68195.0 67162.0 44807.0 67197.0 49273.0 59350.0 True False 27947.74890860003 30241.1085656716 54948.5539947606 68019.20683548566 58727.30138138488 62962.34952283102 48794.73619733938 56813.24768344444 51877.47018717683 57272.17456473404 0.4879812774877446 0.5280244515858297 0.9594284556569947 1.1876484060964785 1.0254072213550427 1.0993532199771014 0.8519798063924966 0.9919869136316645 0.9058058399465931 1.0 15.805546761678396 -5.27035641077355 4.446737445465339 1.0108318143754889 0.4969367759289363 0.8374691827010188 0.08745006508596723 0.07030851409136729 3.695632766366034 0.02422119862138949 0.06015059001994753 5.365912533560968e-06 5.27035641077355 -0.5138950384465526 down SPS(ph)PTLGESLAPHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSPTLGESLAPHK 14 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 S(0.02)PS(0.901)PT(0.079)LGESLAPHK 168.82 0.00019016 4532700.0 11210.0 11411.0 20186.0 22623.0 24485.0 22477.0 22170.0 19387.0 18635.0 15741.0 True False 13107.6315924077 12543.808667328212 20667.310795831312 21355.50665475561 19687.340017043174 21298.266551502926 20069.897103099698 18878.11179222445 18907.50162104362 18594.718694312563 0.7049115293374586 0.6745898592789629 1.111461331337735 1.1484716174430467 1.0587597661837607 1.145393318481192 1.0793331930984433 1.0152405154695114 1.016821062575511 1.0 14.182605302202763 -5.2597656339345 24.998954161355893 1.0776300351597916 0.6897506550531228 0.9026029411795085 0.05018989437207945 39.32695561333123 587371.8543128079 0.013633839840196912 0.032432133755926684 5.498375124189816e-06 5.2597656339345 -0.3878793801066688 SPS(ph)PTLGESLAPHK ddPTM_PC-9_Lapatinib_30min_R1 2 SPSPTLGESLAPHK 14 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 S(0.02)PS(0.778)PT(0.202)LGESLAPHK;S(0.4)PS(0.494)PT(0.106)LGESLAPHK 159.66 0.00025936 9250500.0 60702.0 75390.0 73331.0 80352.0 99654.0 101522.0 95073.0 102830.0 95906.0 83887.0 True False 59836.378348616505 75215.43908694782 67302.008245846 86261.35412641444 93792.54764730227 97180.14071934094 99995.41474423831 107607.85719937092 85104.05634504752 98386.75617759867 0.6081751312199521 0.764487437223521 0.684055566628893 0.8767577820200051 0.9533046041074537 0.9877359971490507 1.0163503567872065 1.0937229905733163 0.8649950425383021 1.0 16.586176507280385 -5.950025797133842 1.4852715281836193 1.0004467424879333 0.6737538650961831 0.8122780522298395 0.06444872811602988 0.158949248087512 0.7116216392795882 0.021280668351779046 0.039308073187614694 1.1219518082776692e-06 5.950025797133842 -0.32669287739175024 SPS(ph)PVLR ddPTM_PC-9_AZD4547_30min_R2 1 SPSPVLR 7 0 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3;O43432-2 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 S(0.461)PS(0.539)PVLR 88.37 0.017315999999999998 25294000.0 43417.0 42334.0 58374.0 53350.0 60501.0 62349.0 45361.0 72359.0 49730.0 46014.0 True False 57222.702870298875 56017.63761350933 57599.922619105935 41050.98174928347 52101.480473277625 58450.30717368444 49398.041124099174 61177.57919440386 52358.62627419283 44403.063865571596 1.288710685450405 1.2615714488329086 1.2972060395086085 0.9245078644474531 1.1733757974677752 1.3163575232249802 1.1124917252027846 1.3777783303336093 1.1791669699349208 1.0 15.438371607277132 SPS(ph)PVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPSPVLR 7 0 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3;O43432-2 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 S(0.457)PS(0.543)PVLR;S(0.472)PS(0.528)PVLR;S(0.116)PS(0.884)PVLR;S(0.41)PS(0.59)PVLR 88.177 0.017446 70156300.0 164718.0 161127.0 161978.0 163784.0 202285.0 125155.0 148454.0 130940.0 102102.0 111292.8 True False 192601.5040712049 177122.62370875393 165840.16982498553 154607.7134748921 162648.70636502228 118591.65147721444 134391.36240611493 127502.96374239813 103595.04859199355 131469.3036466798 1.4649921976373759 1.347254597048496 1.2614364359202548 1.175998572947463 1.237161085162026 0.9020482210503397 1.0222261674655864 0.9698306768632388 0.7879789861092019 1.0 17.004366462955574 -6.022853442350009 0.5673097031014352 0.8974351809314154 1.495273846089148 0.8318502088938717 0.08320151329728205 0.4798952128988057 0.28522249140953965 0.057785332985409325 0.1610441323979734 9.487385719894759e-07 6.022853442350009 0.5978386651577325 SPS(ph)PVLR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSPVLR 7 0 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3;O43432-2 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 S(0.411)PS(0.589)PVLR 91.265 0.015373 20190000.0 34662.0 54651.0 66795.0 46227.0 43096.0 45882.0 38631.0 56185.0 59050.0 46271.0 True False 34167.71352376769 54524.45896724744 61303.37293615623 49626.6877887514 40561.178009995965 43919.733816165906 40631.124157065315 58795.56021342667 52399.167175933326 54268.880697768036 0.6296004834529955 1.0047094811279185 1.129622946851703 0.9144593946046217 0.747411361510984 0.8092986855719734 0.7487002428398415 1.083412067053095 0.965547225264375 1.0 15.727837532776801 -7.7744128680610745 24.996865344931656 1.0183597332395897 0.8675734373439954 0.22410778137826937 0.13624590919348806 423.5090087497292 815989.9477091507 0.07945272965568057 0.03854216126174585 1.6810751638087105e-08 7.7744128680610745 -0.15078629589559434 SPS(ph)PVQGK ddPTM_PC-9_AZD4547_30min_R2 2 SPSPVQGK 8 0 A0A0A6YYC7;Q96JP5-2;Q96JP5 A0A0A6YYC7 ZFP91-CNTF;ZFP91 E3 ubiquitin-protein ligase ZFP91 1 S(0.005)PS(0.995)PVQGK;S(0.011)PS(0.989)PVQGK 95.48299999999999 0.0064128 80340000.0 104917.0 90359.0 127006.0 135029.0 128080.0 128004.0 125746.0 124980.0 110089.0 127081.0 True False 138278.42359083195 119565.77968344814 125321.81745575382 103900.15022725397 110298.30282172868 119999.88964474655 136937.15039771984 105667.21275468977 115908.07978885215 122631.93287044596 1.1275890410772182 0.9749971062574946 1.0219346178629474 0.8472519986863363 0.8994256246311709 0.9785370485150876 1.116651651755229 0.8616614798555079 0.9451704550013315 1.0 16.903975174470148 -4.328319608949092 1.5210410814893713 0.9536139107809509 1.4717986999585604 0.3077977798955953 0.07529436616426022 5.029524516806715 4.290891291257437 0.02187663784978877 5.500906891553828 4.6954842815005826e-05 4.328319608949092 0.5181847891776095 SPS(ph)PVQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPSPVQGK 8 0 A0A0A6YYC7;Q96JP5-2;Q96JP5 A0A0A6YYC7 ZFP91-CNTF;ZFP91 E3 ubiquitin-protein ligase ZFP91 1 S(0.028)PS(0.972)PVQGK;S(0.041)PS(0.959)PVQGK;S(0.177)PS(0.823)PVQGK 82.831 0.015913999999999998 70775000.0 357039.0 409429.0 369773.0 404117.0 424807.0 385881.0 379983.0 334431.0 370952.0 328722.0 True False 417478.650858309 450074.405298004 378589.7906919121 381475.6346549908 341569.1178525656 365644.72105532285 343988.2594013146 325652.54060893477 376376.4712277637 388316.6964380799 1.0750983789461632 1.1590395402165559 0.9749511009045196 0.9823827771356725 0.8796148117906938 0.9416147294444954 0.8858446277397352 0.8386261615739271 0.9692513216149589 1.0 18.566874214520077 -5.525989717822859 1.7731167609111738 0.9134625548910985 1.121272370620311 0.652893320222089 0.053080554841862845 0.20429575761656926 1.2424769065151695 0.015188376261040781 0.042759583835117576 2.9785869483912393e-06 5.525989717822859 0.20780981572921242 SPS(ph)PVQGK ddPTM_PC-9_Lapatinib_30min_R1 2 SPSPVQGK 8 0 A0A0A6YYC7;Q96JP5-2;Q96JP5 A0A0A6YYC7 ZFP91-CNTF;ZFP91 E3 ubiquitin-protein ligase ZFP91 1 S(0.015)PS(0.985)PVQGK;S(0.033)PS(0.967)PVQGK 89.08 0.010494 88911000.0 136125.0 146346.0 141990.0 131676.0 158375.0 158356.0 153164.0 139841.0 146755.0 108212.0 True False 134183.83253773215 146007.14482847144 130316.13029725038 141359.89229825902 149059.69387723028 151583.48302586563 161094.08248279247 146338.52337466972 130225.9065013393 126916.30001657327 1.0572624045942867 1.1504207482364772 1.026787971917186 1.1138040762281884 1.1744724188915485 1.194357880004942 1.2692938768444724 1.153031748920826 1.0260770798103462 1.0 16.953517842614417 -4.75307853872928 24.297528865231875 1.1330151676609885 1.0572622033616779 0.04415730209491997 0.08095629167938968 684.5464094433918 1989142.868004705 0.020927351798693348 0.22728843407881627 1.765718475561558e-05 4.75307853872928 -0.07575296429931067 SPS(ph)SESSPQHPTPPARPR ddPTM_PC-9_AZD4547_30min_R2 2 SPSSESSPQHPTPPARPR 18 1 O14733;O14733-4;O14733-3;O14733-2 O14733 MAP2K7 Dual specificity mitogen-activated protein kinase kinase 7 1 S(0.072)PS(0.552)S(0.102)ES(0.102)S(0.086)PQHPT(0.087)PPARPR;S(0.263)PS(0.351)S(0.351)ES(0.025)S(0.011)PQHPTPPARPR 120.9 3.4826e-05 8024300.0 3646.5 1527.8600000000001 9397.0 14801.099999999999 10453.0 8465.5 6216.200000000001 14229.6 8432.6 11886.0 True False 4806.011148088187 2021.7108660692684 9272.389640109272 11388.935069715451 9001.78138191388 7936.1509467485575 6769.429757624949 12030.74228367845 8878.330020505897 11469.874757816828 0.41901165004551116 0.1762626801736831 0.8084124574934919 0.9929432805666675 0.7848195008214087 0.6919126070962541 0.5901921250719429 1.048899184838909 0.7740564049712253 1.0 13.485562017872407 -5.27120268100903 24.21977809406599 0.827945512704996 0.2976371688416468 0.6830026094540012 0.14672700445989365 219.70964986329997 545034.3264980623 0.038716938167572455 0.08232016288099119 5.355466647656965e-06 5.27120268100903 -0.5303083438633491 SPS(ph)SESSPQHPTPPARPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSSESSPQHPTPPARPR 18 1 O14733;O14733-4;O14733-3;O14733-2 O14733 MAP2K7 Dual specificity mitogen-activated protein kinase kinase 7 1 S(0.077)PS(0.376)S(0.305)ES(0.077)S(0.145)PQHPT(0.02)PPARPR 79.461 0.0018957000000000002 3664200.0 755.15 804.3 3096.1 3436.2 4852.2 3061.3 2985.3 3338.0 3147.8 3305.0 True False 882.981980107642 884.1455885664785 3169.9227660246347 3243.68085431071 3901.4462418091466 2900.7600388893507 2702.510772299664 3250.381036903348 3193.8306199474705 3904.1703376343958 0.22616379505681508 0.22646183749815527 0.811932495738735 0.8308246243877033 0.9993022599964478 0.7429901331218481 0.6922112865437019 0.832540784804182 0.8180561665459165 1.0 11.930800283233852 -5.265709803474854 6.317140935552563 0.8325676743151054 0.22222129945347627 0.8780803478170282 0.09159578023045646 0.04261987261315035 8.924259124887426 0.02445893882966482 0.05750635435145725 5.423631776121858e-06 5.265709803474854 -0.6103463748616291 SPS(ph)SESSPQHPTPPARPR ddPTM_PC-9_Lapatinib_30min_R1 2 SPSSESSPQHPTPPARPR 18 1 O14733;O14733-4;O14733-3;O14733-2 O14733 MAP2K7 Dual specificity mitogen-activated protein kinase kinase 7 1 S(0.06)PS(0.244)S(0.244)ES(0.197)S(0.242)PQHPT(0.012)PPARPR;S(0.077)PS(0.352)S(0.352)ES(0.111)S(0.092)PQHPT(0.017)PPARPR 70.02 0.004918199999999999 1603700.0 6115.7 1903.74 7421.6 4712.799999999999 5644.4 7438.4 5544.9 5406.6 10037.400000000001 3615.2 True False 6028.488996517976 1899.332006995438 6811.424696204472 5059.395033439927 5312.407489317363 7120.2769717573065 5831.987790595929 5657.810373763681 8906.882313492175 4240.082503048797 1.421785777088828 0.44794694575630045 1.606436830251952 1.1932303274292446 1.252901915351298 1.6792779307094918 1.375442054819095 1.334363274699367 2.100638916126692 1.0 12.049876621521634 -5.746054930519709 0.9997859997668618 1.4960186142297849 0.9758914121908278 0.14256788039151636 0.38326002617782345 1.110748798532124 2.07758963886714 0.14389225656904214 0.44457381150412645 1.7945066393377103e-06 5.746054930519709 -0.5201272020389571 SPS(ph)SLLIANLHLQ ddPTM_PC-9_Lapatinib_30min_R1 1 SPSSLLIANLHLQ 13 0 Q658Y4 Q658Y4 FAM91A1 Protein FAM91A1 1 S(0.26)PS(0.37)S(0.37)LLIANLHLQ 116.9 0.0002669 2756200.0 2730.5 0.0 2084.9 982.28 2006.4 894.46 2530.5 938.77 3234.2 2172.9 True False 2691.562569287625 0.0 1913.487569946737 1054.520147990021 1888.3874967341715 856.2060308880992 2661.5169081684085 982.3886813483765 2869.9303383641573 2548.4828697927464 1.0561430885766616 0.0 0.7508339932857191 0.4137834946780628 0.7409849676124145 0.3359669554921237 1.0443534620991408 0.3854798056493386 1.1261328739469032 1.0 11.315422940535115 -8.10912273208032 0.8623599569140231 1.038404518628379 0.543270579802249 0.19423593630044633 0.3264378483868058 0.8791990057777193 1.3145678931765052 0.2812230611479018 0.10815340092788318 7.778167081522495e-09 8.10912273208032 -0.49513393882613 SPS(ph)TTYLHTPTPSEDAAIPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSTTYLHTPTPSEDAAIPSK 21 0 Q13111 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 S(0.073)PS(0.241)T(0.241)T(0.241)Y(0.203)LHTPTPSEDAAIPSK;S(0.195)PS(0.241)T(0.241)T(0.186)Y(0.101)LHT(0.036)PTPSEDAAIPSK 89.62200000000001 0.0002423 14151200.0 85453.0 91784.0 114044.0 123925.0 119157.0 140451.0 130649.0 103958.0 127350.0 109563.0 True False 99918.50512631693 100895.70894067589 116763.2414742783 116981.88402027107 95809.04122568163 133085.50231014533 118272.98090315165 101229.21265260584 129212.25282747032 129425.90459976891 0.7720131872773122 0.7795634826944531 0.9021628385395637 0.9038521645417184 0.7402617082102488 1.0282756201062933 0.9138277323144383 0.782140275284478 0.9983492348540327 1.0 16.981766876136057 -1.5228787452803436 0.1317236959170101 1.014769217237259 0.235901647295267 0.33335691403042933 0.08302735799990804 107.82758847979147 0.9622309316615151 0.43437037217979335 15.625956212099194 0.029999999999999583 1.5228787452803436 -0.7788675699419921 SPS(ph)VAAMASPQLCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSVAAMASPQLCR 14 0 P25325-2 P25325-2 MPST 3-mercaptopyruvate sulfurtransferase 1 S(0.321)PS(0.679)VAAMASPQLCR 116.79 0.00012286 4866500.0 7029.1 10950.0 9426.2 9820.4 11676.0 6027.7 8213.5 5990.3 5928.7 5831.3 True False 8218.987798946742 12037.043633971087 9650.956357062576 9270.194826166371 9388.171616867317 5711.5968008406 7435.4578194095375 5833.060972247496 6015.396021501546 6888.468529454595 1.1931516800581932 1.7474194129655316 1.401030768420554 1.3457555604018057 1.3628822686384023 0.8291533562820566 1.0794065165016078 0.8467863280939365 0.8732559342878821 1.0 12.74996755778773 -6.69311160882902 5.423601741317005 0.9260570181180786 1.4315640320642484 0.7319751051416687 0.146538881826274 0.10302945404887459 5.619008474113783 0.048530924624597724 0.04795378214169451 2.0271616946714466e-07 6.69311160882902 0.5055070139461698 SPS(ph)VAAMASPQLCR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSVAAMASPQLCR 14 0 P25325-2 P25325-2 MPST 3-mercaptopyruvate sulfurtransferase 1 S(0.179)PS(0.82)VAAMASPQLCR 82.515 0.0080594 22027000.0 16374.0 22309.0 30632.0 22642.0 23451.0 28812.0 28242.0 25533.0 28315.0 25623.0 True False 16140.503757376158 22257.344881160865 28113.55520293945 24307.16821149782 22071.658286439913 27579.777924052418 29704.232570832708 26719.3563927992 25125.866529831535 30051.90140949862 0.5370876051215371 0.7406301710455466 0.9355000477292092 0.8088396098562656 0.7344513076122244 0.917738200596358 0.988431053532073 0.8891070161821412 0.8360824224549701 1.0 14.875168653922572 -4.882019243837773 2.540997964844463 0.8810263022725642 0.5007375427706436 0.6650786408180427 0.07741698713545102 0.2557192219816249 2.5220061014579302 0.021359132062062688 0.19370380095376522 1.3121417559766766e-05 4.882019243837773 -0.38028875950192054 SPSDLHIS(ph)PLAK ddPTM_PC-9_AZD4547_30min_R2 3 SPSDLHISPLAK 12 0 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785;O95785-2 B9EGQ5 WIZ Protein Wiz 1 S(0.064)PS(0.001)DLHIS(0.935)PLAK;SPSDLHIS(1)PLAK;SPSDLHIS(1)PLAK 120.53 0.00048863 8086500.0 72095.0 58229.0 117078.0 175482.0 158320.0 118802.0 103466.0 143580.0 104247.0 134606.0 True False 95019.71033084273 77050.38551984308 115525.46922259385 135027.3360698736 136340.00080212395 111373.29215942623 112674.27355979914 121393.01014016937 109757.28359553152 129893.48491087776 0.7315202174769385 0.5931812944483608 0.8893861713068822 1.0395235462542118 1.0496292473457716 0.8574201564908466 0.8674359121021887 0.9345581129296768 0.844979127866482 1.0 16.986969545542202 -5.360742201554258 5.1676321118331 0.9385326828391809 0.6641160171871309 0.6791919682849781 0.07554289194893025 0.12284183755423818 4.996373392682168 0.02106563460133012 0.04543537787385204 4.357704715231666e-06 5.360742201554258 -0.27441666565205003 SPSDLHIS(ph)PLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSDLHISPLAK 12 0 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785;O95785-2 B9EGQ5 WIZ Protein Wiz 1 SPSDLHIS(1)PLAK 90.444 0.0039357 5610900.0 44044.0 59516.0 82175.0 90550.0 95362.0 91621.0 94148.0 109540.0 85980.0 64780.0 True False 51499.77929134743 65424.355152458724 84134.36365042301 85476.77706706084 76676.50066184487 86816.23347044755 85229.61986750698 106664.69106722371 87237.29484182072 76524.10120180219 0.672987705605807 0.8549509778615726 1.0994492235662037 1.1169915846727752 1.0019915223785614 1.13449530418533 1.11376178914859 1.3938705504810516 1.1399976408970385 1.0 16.223626574521347 -4.344186039719888 0.7476792359374914 1.162046675250259 1.4696029368199507e-13 0.6736536170068383 0.10368001153473144 2.8839334170979702 0.7774267887346414 0.04186958132048585 3.2672241527173367 4.5270361268017805e-05 4.344186039719888 -1.162046675250112 SPSDLHIS(ph)PLAK ddPTM_PC-9_Lapatinib_30min_R1 1 SPSDLHISPLAK 12 0 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785;O95785-2 B9EGQ5 WIZ Protein Wiz 1 SPSDLHIS(1)PLAK 67.648 0.020622 4666100.0 89225.0 71054.0 95924.0 76618.0 93763.0 89236.0 71536.0 78144.0 104350.0 64817.0 True False 87952.63513813881 70889.47882854483 88037.49899734784 82252.74331015532 88248.04468515053 85419.584299276 75239.78405166374 81774.85551869751 92597.0041457856 76020.53208677641 1.1569589520597154 0.9325043758918373 1.1580752802000152 1.0819806314465799 1.1608448699677159 1.1236383376239816 0.9897297741323166 1.0756943324910253 1.2180525655896142 1.0 16.214101502569207 SPSDS(ph)DMEDYSPPPSLSEVARKMKK ddPTM_PC-9_Lapatinib_30min_R1 1 SPSDSDMEDYSPPPSLSEVARKMKK 25 3 A0A590UJS4;Q6KC79-2;Q6KC79 A0A590UJS4 NIPBL Nipped-B-like protein 1 S(0.035)PS(0.137)DS(0.58)DMEDY(0.076)S(0.083)PPPS(0.083)LS(0.006)EVARKMKK 47.099 0.035707 0.0 3734.7 1748.9 4415.7 4016.8 3055.4 3266.8 3211.0 2121.0 3911.9 3166.4 True False 3681.4424931399008 1744.850529502095 4052.658191094925 4312.208871651995 2875.6873791475214 3127.0865792827435 3377.249868456336 2219.549403091181 3471.300627866784 3713.7080210372087 0.9913117758007544 0.46984052586201225 1.0912700104956152 1.1611599100479713 0.7743439610377245 0.8420388898557979 0.9094010216541195 0.5976639494860662 0.9347263188712606 1.0 11.858644676898143 SPSDSSTAS(ph)TPVAEQIER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPSDSSTASTPVAEQIER 18 0 Q16643-3;Q16643;Q16643-2;D6R9Q9 Q16643-3 DBN1 Drebrin 1 SPSDS(0.017)S(0.078)T(0.029)AS(0.438)T(0.438)PVAEQIER;SPSDSS(0.001)T(0.012)AS(0.717)T(0.27)PVAEQIER;SPSDSS(0.007)TAS(0.734)T(0.258)PVAEQIER;SPSDSST(0.007)AS(0.726)T(0.267)PVAEQIER 235.02 2.9128999999999995e-81 57934000.0 45869.9 44469.1 47928.3 53536.1 82744.0 70162.0 74749.0 70810.0 70857.0 58369.9 True False 53634.76809817855 48883.69836195646 49071.092441089924 50536.645883378 66530.90718277388 66482.58120685803 67668.2335841047 68951.31252939679 71893.14957672596 68951.90081412582 0.7778577162471882 0.7089536007677675 0.7116713515030028 0.7329260729100134 0.9648886600258021 0.964187794997496 0.9813831494873286 0.9999914681869232 1.0426565290858172 1.0 16.073302702968384 -6.288535151576058 4.017845185310613 0.9935390975442413 0.7272994418204567 0.9599179412551827 0.026008800135017586 0.041764464175995414 1.5440350691603009 0.008726465782603358 0.01044924402008361 5.14594154337081e-07 6.288535151576058 -0.2662396557237846 SPSDSSTAS(ph)TPVAEQIER ddPTM_PC-9_Lapatinib_30min_R1 2 SPSDSSTASTPVAEQIER 18 0 Q16643-3;Q16643;Q16643-2;D6R9Q9 Q16643-3 DBN1 Drebrin 1 SPSDSST(0.009)AS(0.698)T(0.293)PVAEQIER;SPSDS(0.006)S(0.114)T(0.042)AS(0.606)T(0.233)PVAEQIER 221.81 2.5675999999999996e-28 58414000.0 28896.0 21796.0 28902.0 23267.0 42606.0 34703.0 36371.0 32775.0 42593.0 39460.0 True False 28483.937741122583 21745.53270114226 26525.789124946317 24978.132796436683 40099.99884661887 33218.83358664412 38254.11241533021 34297.84615101999 37795.727815826016 46280.60842285504 0.6154616093390896 0.4698627231184698 0.5731512620272062 0.5397105536776301 0.8664535798716086 0.7177700276351479 0.8265689177162793 0.7410845993563575 0.8166644541596199 1.0 15.498120210348914 -6.2545959927535035 24.86556573852569 0.809552415680954 0.5455408701090837 0.740908215519245 0.08023243845485513 252.90783819805532 918944.3198774412 0.0223187685821973 0.028165702170974055 5.564216339662207e-07 6.2545959927535035 -0.26401154557187034 SPSDSSTAST(ph)PVAEQIER ddPTM_PC-9_AZD4547_30min_R2 2 SPSDSSTASTPVAEQIER 18 0 Q16643-3;Q16643;Q16643-2;D6R9Q9 Q16643-3 DBN1 Drebrin 1 SPSDSST(0.004)AS(0.235)T(0.761)PVAEQIER;SPSDS(0.003)S(0.003)T(0.006)AS(0.225)T(0.764)PVAEQIER 233.57 8.5889e-43 67184000.0 20958.0 23665.0 30161.0 48188.0 54196.0 48183.0 34666.0 56431.0 32475.0 45055.0 True False 27622.208046519187 31314.248455702214 29761.045433152703 37079.00109717847 46671.82089105561 45170.109393087885 37751.20684305949 47710.88560537605 34191.5622009735 43477.63816367468 0.6353198842709304 0.7202380298998184 0.6845138487310446 0.8528292396563014 1.073467254945087 1.0389273958038332 0.8682901932469829 1.0973660856591383 0.7864171938746286 1.0 15.407985950501088 -5.9259467266788635 3.328057788813783 0.9797220698451417 0.6831109474071758 0.6850153510334929 0.09004173897395668 0.1323146941518875 2.951560287059947 0.025389719891157105 0.03916204078991089 1.1859142110190097e-06 5.9259467266788635 -0.29661112243796584 SPSEGQTATT(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 SPSEGQTATTSPR 13 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 SPSEGQT(0.001)AT(0.02)T(0.755)S(0.224)PR 138.31 0.00015522 2477600.0 5359.9 8628.5 11081.0 13301.0 11809.0 10867.0 7989.9 11777.0 6211.1 8443.1 True False 7064.236707154227 11417.493885486023 10934.058699803227 10234.659948401484 10169.524188177651 10187.48477211228 8700.985621512747 9957.135258537213 6539.406065788034 8147.5096388796355 0.8670424485837896 1.4013476990566707 1.342012367512433 1.2561703394080124 1.2481757787249532 1.2503802049521922 1.06793192118386 1.22210782188242 0.8026263675199858 1.0 12.992143438401701 -8.250550418825116 24.51664020377638 0.9013131892738045 1.2177174838827558 0.40563933275650166 0.147495294157129 450.09382275664666 1013399.5721033023 0.09953562038454804 0.036768116702112816 5.616290730100767e-09 8.250550418825116 0.31640429460895125 SPSEGQTATT(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSEGQTATTSPR 13 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 SPSEGQT(0.001)AT(0.085)T(0.613)S(0.301)PR 115.12 0.00071971 4000500.0 16078.0 16737.0 22684.0 20986.0 24949.0 21554.0 22461.0 22243.0 17228.0 15689.0 True False 18799.687845025062 18398.53874902045 23224.872589549075 19810.22245752998 20060.422547895036 20423.670296351564 20333.331476442163 21659.144818406592 17479.92690782611 18533.291505944326 1.014373935627964 0.9927291513824915 1.2531434355359912 1.068899307560996 1.0823993429046805 1.1019990857965474 1.0971246780379242 1.1686615306007402 0.9431636524046275 1.0 14.177831505793185 -8.273598426971063 24.98572022684219 0.971581807695025 1.097809547484423 0.33691892495028763 0.07061055230438408 990.4748200098142 2035312.8240234943 0.06652631332160198 0.01767146620048908 5.326005039421594e-09 8.273598426971063 0.12622773978939794 SPSEGQTATTS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 SPSEGQTATTSPR 13 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 SPSEGQT(0.001)AT(0.019)T(0.35)S(0.629)PR;SPSEGQT(0.005)AT(0.032)T(0.213)S(0.751)PR 101.61 0.0019593 8615400.0 28489.5 26748.4 31876.7 50940.0 39177.0 30169.9 27599.3 39299.0 37618.0 30405.8 True False 37548.56838158739 35394.29720652886 31453.99413013422 39196.5700151546 33737.94979424469 28283.371383652375 30055.584233071368 33226.242551180614 39606.41068133088 29341.30219680522 1.2797171757999142 1.2062960590202678 1.0720040276044407 1.3358837911230284 1.1498450057856735 0.9639439720140289 1.0243439105556782 1.1324051784858546 1.3498518373749397 1.0 14.840645280253453 -6.5202738472904445 24.999466075435734 1.0934540405605806 1.215358258257879 0.21250956779588848 0.11697896401454994 185.40237814287366 1779352.556355521 0.03951807698257088 0.04019044421236783 3.0180480698879194e-07 6.5202738472904445 0.12190421769729842 SPSEGQTATTS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSEGQTATTSPR 13 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 SPSEGQT(0.001)AT(0.019)T(0.069)S(0.912)PR;SPSEGQTAT(0.001)T(0.005)S(0.995)PR 143.58 8.6705e-05 8075000.0 22550.0 21646.0 31919.0 27622.0 30175.0 26241.0 27407.0 29677.0 26587.0 20233.1 True False 26367.26961719835 23794.871826569677 32680.070013481592 26074.42889173226 24262.42536304994 24864.875765359615 24810.810550503094 28898.01019538068 26975.784577337643 23901.20086486854 1.103177608785113 0.9955513097898293 1.367298245734455 1.0909254743789072 1.0151132363693218 1.0403190996945908 1.03805707047011 1.2090610157524244 1.1286372065509191 1.0 14.544795484712271 SPSEGQTATTS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 SPSEGQTATTSPR 13 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 SPSEGQTAT(0.054)T(0.378)S(0.568)PR;SPSEGQTAT(0.013)T(0.053)S(0.934)PR;SPSEGQT(0.003)AT(0.032)T(0.213)S(0.752)PR 138.55 6.4544e-05 10054700.0 46487.0 34366.6 41686.0 37283.0 38451.3 35437.3 38013.8 32811.3 43092.2 34980.9 True False 45824.08685532828 34287.02624917763 38258.7379926134 40024.916192442055 36189.6701321644 33921.729287381044 39981.9685610481 34335.83278153968 38238.70265501697 41027.30195588063 1.1169168985229871 0.835712430860034 0.9325189853760198 0.9755678361566035 0.8820874980051464 0.8268086778862358 0.974521030021505 0.8369020419247472 0.9320306437927011 1.0 15.324296662152882 -4.749194561375539 24.971657796010042 0.906776674558292 1.1169173867215096 0.5127174809298104 0.06020762642200125 444.2578620519036 905948.1533532196 0.014269183221352276 0.2395445832462182 1.7815804510692075e-05 4.749194561375539 0.2101407121632176 SPSFGDPQLS(ph)PEAR ddPTM_PC-9_AZD4547_30min_R2 2 SPSFGDPQLSPEAR 14 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 SPS(0.001)FGDPQLS(0.999)PEAR;SPSFGDPQLS(1)PEAR 157.07 0.00037702 23476000.0 69743.0 86885.0 78060.0 83976.0 86485.0 83740.0 78822.0 107330.0 96311.0 78036.0 True False 91919.82325548198 114968.87712122063 77024.87339650215 64616.6306162666 74478.0505897658 78503.72456213147 85837.00530155298 90744.61469803841 101401.80283719666 75303.9833923097 1.2206502115115088 1.5267303526596927 1.0228525760081928 0.858077192007687 0.9890320170947524 1.042490994840899 1.1398733697043568 1.2050440177286232 1.3465662541239771 1.0 16.200438561423177 -5.273849604853491 24.941713691235844 1.073083093543925 1.3736902870639323 0.4089021160053461 0.14338844629142933 663.6855287805259 1333856.5879225663 0.040551245095272574 0.08537053336831422 5.322925590012812e-06 5.273849604853491 0.3006071935200072 SPSFGDPQLS(ph)PEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSFGDPQLSPEAR 14 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 S(0.07)PS(0.007)FGDPQLS(0.923)PEAR;SPSFGDPQLS(1)PEAR 130.21 2.0162e-05 21349000.0 42641.0 77073.0 69107.0 52779.0 61611.0 41208.0 49472.0 31755.0 35807.0 38603.0 True False 49859.27910186053 84724.29808228798 70754.77296975706 49821.963741826694 49538.76682826411 39046.97993746197 44785.654013737 30921.464897203667 36330.609634811335 45601.41831882015 1.0933712358083196 1.8579312049011738 1.5515914982090782 1.0925529419611206 1.086342676491248 0.8562667868018241 0.9821109883166403 0.6780812096899643 0.7966991153829384 1.0 15.476791076082161 -6.0581223285758625 1.633370067847714 0.8614072626962436 1.539863224760116 0.6260605632500931 0.20574138172755402 0.2261771593843302 1.210160745956753 0.06961848285172066 0.11154612518769076 8.747373515436244e-07 6.0581223285758625 0.6784559620638725 SPSFGDPQLS(ph)PEAR ddPTM_PC-9_Lapatinib_30min_R1 2 SPSFGDPQLSPEAR 14 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 SPSFGDPQLS(1)PEAR;SPSFGDPQLS(1)PEAR 85.976 0.0066827 22314000.0 28539.0 54392.0 49557.0 45222.0 52937.0 56834.0 56954.0 60368.0 52930.0 46600.0 True False 28132.028626588388 54266.05866583449 45482.61475555205 48547.77673616971 49823.349738146346 54403.34230652486 59902.79944193776 63172.917664218934 46968.46602239035 54654.747909403086 0.5147225026674839 0.9928882803702087 0.8321804874289245 0.8882627510540086 0.9116014919826294 0.995400114125584 1.0960218779388382 1.1558541587079636 0.8593666208148341 1.0 15.738059209166998 -4.143190055353265 0.6355026958694103 1.0152303668320082 2.6073830085892852e-33 0.556560594610792 0.11153004433555963 5.764684230640358 0.9770730669472978 0.05087280613565047 5.109651057099839 7.191342026132417e-05 4.143190055353265 -1.0152303668320082 SPSFGDPQLS(ph)PEARPR ddPTM_PC-9_AZD4547_30min_R2 3 SPSFGDPQLSPEARPR 16 1 O95425-2;O95425-3 O95425-2 SVIL Supervillin 1 SPSFGDPQLS(1)PEARPR;SPSFGDPQLS(1)PEARPR;SPSFGDPQLS(1)PEARPR 129.06 8.8474e-06 170956000.0 117751.0 120920.0 143402.0 219127.0 177770.0 160968.0 131944.0 191849.0 140155.0 156324.0 True False 155193.36862704833 160005.0252805205 141500.39578279783 168610.65562840184 153089.70403356294 150902.64551369965 143686.7603906033 162203.14530144428 147563.30716789654 150851.1443413225 1.0287848282801284 1.0606815478872735 0.9380134065316252 1.1177287143867858 1.0148395274163473 1.0003414039224032 0.9525069300468232 1.0752529986410726 0.9782047581555844 1.0 17.202766115099678 -6.512551177400922 24.849728107946955 1.0034366108144985 1.0354305385628195 0.09641808547136066 0.05035308255322947 1289.2565592971096 3102150.122935767 0.01571793174957204 0.016651353822135045 3.0721953154553423e-07 6.512551177400922 0.031993927748320994 SPSFGDPQLS(ph)PEARPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPSFGDPQLSPEARPR 16 1 O95425-2;O95425-3 O95425-2 SVIL Supervillin 1 SPSFGDPQLS(1)PEARPR;SPSFGDPQLS(1)PEARPR;SPSFGDPQLS(1)PEARPR;SPSFGDPQLS(1)PEARPR 147.1 1.4167999999999999e-05 146095000.0 148294.0 139525.0 162591.0 171350.0 183927.0 150452.0 167438.0 145156.0 152106.0 135913.0 True False 173397.24525999153 153376.1199113986 166467.78606980105 161749.81502419538 147887.82468101676 142562.0322643911 151577.06049385725 141345.80880549518 154330.2624937197 160552.95101328424 1.080000362283248 0.9552992887605546 1.0368404007474605 1.0074546372605266 0.9211155805462613 0.8879440170028108 0.9440938926206076 0.8803687999095087 0.9612421417339774 1.0 17.292689656928736 -6.231733647383677 5.395307133087055 0.9246752221141032 1.0173486965913 0.48769545784584756 0.043493725564157044 0.1507453483622144 12.989717241480568 0.012275155818674569 0.015529272482732082 5.864977530511424e-07 6.231733647383677 0.09267347447719665 SPSFGDPQLS(ph)PEARPR ddPTM_PC-9_Lapatinib_30min_R1 2 SPSFGDPQLSPEARPR 16 1 O95425-2;O95425-3 O95425-2 SVIL Supervillin 1 SPSFGDPQLS(1)PEARPR;SPSFGDPQLS(1)PEARPR 103.45 0.00064284 135748000.0 211038.0 158801.0 201684.0 153717.0 169474.0 155241.0 157286.0 136013.0 172915.0 127975.0 True False 208028.55942037096 158433.30604120405 185102.32004275388 165021.86096487966 159505.87251870366 148601.70431444596 165429.4994736915 142332.66051986866 153439.4918243271 150095.30823403105 1.3859764296963197 1.0555513553706306 1.2332318859303673 1.0994471639818006 1.0626972581314766 0.9900489633076589 1.1021630284122614 0.948281876325816 1.0222804005644317 1.0 17.195519355504096 -1.5228787452855401 0.3719807838536284 0.9985444202288295 5.331731153713514 0.6570163490896803 0.0724517727767328 40.84258646825542 0.5630002573334418 0.054611162754351295 126.67854721190145 0.02999999999964062 1.5228787452855401 4.333186733484685 SPSGPVKS(ph)PPLSPVGTTPVK ddPTM_PC-9_AZD4547_30min_R2 1 SPSGPVKSPPLSPVGTTPVK 20 1 C9J4K0;Q9BVC5-2;Q9BVC5 C9J4K0 C2orf49 Ashwin 1 S(0.002)PS(0.025)GPVKS(0.97)PPLS(0.003)PVGTTPVK 73.11 0.0014118 9352100.0 28169.0 23916.0 33676.0 43703.0 41018.0 42544.0 24190.0 35654.0 26905.0 27760.0 True False 37126.15604840153 31646.379297129693 33229.43423649248 33627.94855461921 35323.35872221786 39883.71695451781 26342.86313776062 30144.49354741326 28327.143372353883 26788.130849486406 1.3859181238512326 1.1813582468646344 1.2404536331107838 1.2553301588514503 1.3186197618896243 1.4888577772973839 0.9833781716900072 1.1252929036663715 1.0574512843585346 1.0 14.70930629972739 -7.27976014307265 24.972165670598265 1.0519716521649807 1.300335231960086 0.6966583999290827 0.08705083575598876 530.7070837417576 723378.9156484292 0.03759994231345329 0.025405361448834464 5.2509738673364407e-08 7.27976014307265 0.24836357979510537 SPSGPVKS(ph)PPLSPVGTTPVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSGPVKSPPLSPVGTTPVK 20 1 C9J4K0;Q9BVC5-2;Q9BVC5 C9J4K0 C2orf49 Ashwin 1 S(0.009)PS(0.009)GPVKS(0.959)PPLS(0.022)PVGTTPVK;S(0.003)PS(0.015)GPVKS(0.981)PPLSPVGTTPVK 85.01299999999999 0.00036889 21653000.0 79799.0 90929.0 78662.0 87568.0 107936.0 81870.0 89309.0 70301.0 70164.0 69315.0 True False 93307.3945979074 99955.8301911739 80537.60040729606 82661.84885928656 86786.7156250593 77576.59307610197 80849.00497883323 68455.67324006661 71190.01576275328 81881.2608027619 1.1395451618981434 1.2207412198005911 0.9835901354926314 1.009533170946219 1.0599093708890708 0.9474279257004952 0.9873932592902398 0.8360358959904726 0.8694298923197822 1.0 16.32124569661385 -5.3016249435905385 0.4909504989081616 0.905830905921043 1.2921452033149492 0.6179345378615714 0.06734810222633988 1.8737395301625315 0.5030591388895006 0.04855258071046718 0.39546786609551415 4.9931550984142e-06 5.3016249435905385 0.3863142973939062 SPSGPVKS(ph)PPLSPVGTTPVK ddPTM_PC-9_Lapatinib_30min_R1 2 SPSGPVKSPPLSPVGTTPVK 20 1 C9J4K0;Q9BVC5-2;Q9BVC5 C9J4K0 C2orf49 Ashwin 1 S(0.008)PS(0.008)GPVKS(0.981)PPLS(0.002)PVGTTPVK;S(0.024)PS(0.085)GPVKS(0.879)PPLS(0.011)PVGT(0.001)TPVK 62.678000000000004 0.0045192 15659400.0 77702.0 64847.0 71069.0 54692.0 66575.0 63646.0 47952.0 50301.0 51641.0 46304.0 True False 76593.95523119847 64696.85075568783 65225.98115427342 58714.23212716361 62659.18939148593 60924.008946072456 50434.719929062056 52638.168092828615 45824.646776162124 54307.584703798304 1.4103730749388574 1.1913041448732096 1.2010473584864008 1.081142393781639 1.1537833938525996 1.121832415828491 0.9286864846621438 0.9692599731681139 0.8437982839063201 1.0 15.728866081269718 -4.572591701299481 0.32032642820782303 0.9082501075743438 1.7650088606740284 0.7847437386454721 0.07183225460854868 3.8801179419297434 0.29134132188663237 0.07753890923836158 1.3331449514231646 2.6755205972569472e-05 4.572591701299481 0.8567587530996846 SPSGSAFGS(ph)QENLR ddPTM_PC-9_AZD4547_30min_R2 3 SPSGSAFGSQENLR 14 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 SPSGSAFGS(1)QENLR;SPSGSAFGS(1)QENLR;S(0.02)PS(0.006)GS(0.001)AFGS(0.972)QENLR 185.74 5.6102999999999995e-06 66327900.0 23501.199999999997 34538.6 52893.8 64737.0 57696.7 52324.4 53959.7 55277.0 41604.9 52578.0 True False 30974.09274467301 45702.52701086489 52192.39365180505 49812.8848266797 49686.50912253614 49052.546996403034 58762.00876621005 46735.2097890941 43804.05007591323 50737.260223497695 0.6104801995265825 0.9007685241486277 1.0286797793553986 0.9817811329830164 0.9792903460625781 0.9667953448871008 1.158162827621423 0.9211220626266662 0.8633507186425978 1.0 15.630757996533257 -4.778255045196423 2.86910797950804 0.9890966952440382 0.5414376388248155 0.7122042200669254 0.07185631751924826 0.22926738565340277 2.6216868677243705 0.01898522273911196 0.24428455130208532 1.6662683869478757e-05 4.778255045196423 -0.44765905641922266 SPSGSAFGS(ph)QENLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SPSGSAFGSQENLR 14 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 SPSGSAFGS(1)QENLR;SPSGS(0.013)AFGS(0.987)QENLR;SPSGSAFGS(1)QENLR;S(0.001)PS(0.001)GS(0.002)AFGS(0.996)QENLR;SPSGSAFGS(1)QENLR 173.19 3.0415999999999998e-05 62772900.0 32259.4 53713.5 60742.100000000006 55664.9 65728.7 52182.6 66235.3 52792.9 65822.5 41939.0 True False 37720.279267807025 59045.82129984524 62190.422029697074 52546.17612104076 52849.63307242085 49446.0525937828 59961.01288195487 51407.14231370123 66785.02953856425 49542.20871105864 0.7613766170135897 1.1918286010261234 1.2553017648527878 1.0606345071836003 1.0667597276627665 0.998059107177949 1.2103015679349511 1.03764332780396 1.3480430379692927 1.0 15.59637056838926 -7.268226047381499 24.838787382272205 1.1521339210863608 1.0716547989284841 0.07816331407356114 0.15100295543159892 1613.1146264293225 5903877.285343151 0.06134734874062254 0.042376503297103116 5.392298839017578e-08 7.268226047381499 -0.08047912215787667 SPSGSAFGS(ph)QENLR ddPTM_PC-9_Lapatinib_30min_R1 2 SPSGSAFGSQENLR 14 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 SPSGS(0.003)AFGS(0.997)QENLR;SPSGSAFGS(1)QENLR 154.47 2.4846e-05 34772300.0 29414.0 37265.0 34457.0 33461.0 36502.0 36069.0 30667.0 37353.0 39706.0 25304.0 True False 28994.55096613302 37178.715182054795 31624.078467866417 35921.83356262382 34355.02412569316 34526.41295094566 32254.78720521658 39088.55674383065 35233.8921572838 29677.762684539404 0.9769790018988762 1.252746562375573 1.0655816209602937 1.2103956064497159 1.15760155139964 1.1633765428325955 1.0868335173398929 1.3170991748712173 1.1872152403064689 1.0 14.857094715255387 -4.744324219244149 24.99276808874297 1.1663574152504728 0.9769784351761813 0.279717331420849 0.08763603067672761 1329.0374338194388 1940651.11084106 0.020509495945002607 0.5949169045433669 1.801672213979803e-05 4.744324219244149 -0.18937898007429144 SPSGSQRPS(ph)VSDDTEHLVNGR ddPTM_PC-9_AZD4547_30min_R2 2 SPSGSQRPSVSDDTEHLVNGR 21 1 P16144-4;P16144-2;P16144-3 P16144-4 ITGB4 Integrin beta-4 1 S(0.056)PS(0.056)GS(0.048)QRPS(0.766)VS(0.065)DDT(0.009)EHLVNGR;S(0.102)PS(0.102)GS(0.087)QRPS(0.354)VS(0.354)DDT(0.001)EHLVNGR 64.249 0.0022096999999999998 33700000.0 42740.0 53442.0 59913.0 68628.0 60013.0 40223.0 39151.0 58079.0 47972.0 38550.0 True False 56330.430952773655 70716.08138473016 59118.51447354121 52806.874892030486 51681.23084978451 37707.84945142842 42635.36315446321 49104.225072648595 50507.70198322095 37200.376233706775 1.5142435818090836 1.9009507038440983 1.58919130554316 1.419525290827109 1.3892663484128105 1.0136416151958654 1.1461003213142738 1.31999270018554 1.357720192556993 1.0 15.183029591951524 -6.010622878166869 1.5138375177989793 1.1943867911532011 1.7121038299618607 0.6735395657682196 0.1478962465943116 0.2353632895485308 1.0899524773454174 0.05193321103818742 0.08941480787244929 9.758366426499845e-07 6.010622878166869 0.5177170388086596 SPSGSQRPS(ph)VSDDTEHLVNGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSGSQRPSVSDDTEHLVNGR 21 1 P16144-4;P16144-2;P16144-3 P16144-4 ITGB4 Integrin beta-4 1 S(0.012)PS(0.049)GS(0.04)QRPS(0.869)VS(0.03)DDT(0.001)EHLVNGR;S(0.01)PS(0.036)GS(0.025)QRPS(0.919)VS(0.009)DDT(0.001)EHLVNGR 77.89399999999999 0.00054884 23849000.0 43791.0 66934.0 64874.0 47513.0 101503.0 73038.0 69980.0 65869.0 61791.0 54713.0 True False 51203.95138832521 73578.76516860462 66420.84219601509 44851.00064922434 81614.2157953822 69207.75870394944 63350.98778867467 64140.00854397446 62694.57647791287 64632.033792130285 0.7922379721641979 1.138425651361194 1.0276768082161545 0.6939438234834795 1.2627517812277123 1.0707965484505038 0.9801793951343738 0.9923872850769592 0.9700232655458644 1.0 15.979961769519864 -6.269515238688821 24.987471837775384 1.043588882007193 0.9373539415430561 0.17279771549338563 0.1384276362446705 1387.6811508530268 4293607.97560199 0.04355777086467549 0.05023987697660087 5.3763156817175e-07 6.269515238688821 -0.10623494046413695 SPSGSQRPS(ph)VSDDTEHLVNGR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSGSQRPSVSDDTEHLVNGR 21 1 P16144-4;P16144-2;P16144-3 P16144-4 ITGB4 Integrin beta-4 1 S(0.001)PS(0.003)GS(0.003)QRPS(0.919)VS(0.072)DDT(0.003)EHLVNGR 67.217 0.0017687000000000002 11162000.0 13499.0 16563.0 12901.0 8455.9 18110.0 11905.0 10685.0 10043.0 24105.0 10444.0 True False 13306.501784586588 16524.649391127678 11840.329579300138 9077.775094055485 17044.805405629908 11395.85090191045 11238.217017893467 10509.634443774039 21390.0410630969 12249.231484244767 1.08631319456259 1.3490356037749835 0.9666181584150346 0.7410893577879984 1.3914999832890182 0.9303319082971079 0.9174630287906886 0.8579831687638334 1.74623535285534 1.0 13.580403617050836 -8.238273762103884 24.91412137652286 1.3731179927947799 1.0339013797855245 0.22350042898333822 0.2557077926876098 961.4833518794678 1034058.0894161096 0.1677844360304007 0.06332284779226015 5.777317532998111e-09 8.238273762103884 -0.3392166130092553 SPSLGS(ph)DLTFATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSLGSDLTFATR 13 0 Q13425 Q13425 SNTB2 Beta-2-syntrophin 1 S(0.089)PS(0.109)LGS(0.799)DLT(0.003)FATR 106.29 0.0011345 8652500.0 33885.0 83726.0 42100.0 50796.0 60230.0 48907.0 81949.0 49944.0 49118.0 61741.0 True False 39621.06124074354 92037.76395414291 43103.8236651391 47950.064802853965 48428.36386467267 46342.23082414708 74186.1974606189 48633.02292004219 49836.25782787341 72934.154558513 0.5432442657432424 1.2619295378313276 0.5909964121207182 0.6574432115256097 0.6640011686955248 0.6353982041015919 1.0171667569149847 0.666807248461697 0.6833047990964397 1.0 16.154306956418665 -9.544629621357018 15.341820550895266 1.000000004262643 0.7545474346273385 0.11447498848698412 0.21033347859363244 0.0 0.0 0.19816377684980516 0.04806177547782792 2.8534507337769227e-10 9.544629621357018 -0.24545256963530437 SPSLS(ph)PSPPS(ph)PLEK ddPTM_PC-9_Lapatinib_30min_R1 2 SPSLSPSPPSPLEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 SPS(0.017)LS(0.948)PS(0.037)PPS(0.999)PLEK;S(0.002)PS(0.021)LS(0.941)PS(0.038)PPS(0.997)PLEK 96.773 0.034727 11529000.0 50382.0 54005.0 52152.0 48602.0 68973.0 76222.0 67936.0 72860.0 72733.0 79327.0 True False 49663.54344107277 53879.95474055731 47864.2638725417 52176.35321151915 64916.14374613544 72962.16274216038 71453.39366659897 76245.34158850691 64541.04362755558 93038.56625341668 0.5337952361153132 0.5791141986625215 0.5144561637178493 0.5608034959330972 0.697733707216834 0.7842141778434916 0.7679975793261429 0.8195025424277422 0.6937020445022757 1.0 16.50554124425586 -6.460732381511107 1.9041677574665699 0.803215667125868 0.5416667341612188 0.7418803897621724 0.07394665603013398 0.1737665096255447 1.2579208859631816 0.025635571443154957 0.029086892806831147 3.461526163261568e-07 6.460732381511107 -0.2615489329646492 SPSLSLAPLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 SPSLSLAPLSPR 12 0 G3V160;Q969H4-2;Q969H4 G3V160 CNKSR1 Connector enhancer of kinase suppressor of ras 1 1 SPSLSLAPLS(1)PR;SPSLSLAPLS(1)PR 115.12 0.00073759 23863000.0 20905.9 27539.0 30103.0 35713.0 30014.0 33886.0 23671.2 36723.0 22409.0 26877.0 True False 27553.54133026653 36440.443195503234 29703.8145510492 27479.91961034977 25847.074179351683 31767.103063200233 25777.89094280937 31048.304160589443 23593.493991119798 25936.044410722123 1.062364826876828 1.4050115976990896 1.145271579607932 1.059526239822037 0.9965696298956961 1.224824516805173 0.9939021746952525 1.1971102327290077 0.909679734407229 1.0 14.662670845870476 -5.4775252119108515 0.300483058459817 0.9999653233255583 1.334434900944348 0.2137465537870311 0.12264853103403557 7.943307847593255 0.8147011262867645 0.14632114840309476 0.9456876173520634 3.330234288816266e-06 5.4775252119108515 0.3344695776187896 SPSLSLAPLS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPSLSLAPLSPR 12 0 G3V160;Q969H4-2;Q969H4 G3V160 CNKSR1 Connector enhancer of kinase suppressor of ras 1 1 SPSLS(0.002)LAPLS(0.998)PR;SPSLSLAPLS(1)PR;SPSLSLAPLS(1)PR;SPSLS(0.001)LAPLS(0.999)PR 133.04 6.9446e-05 22517200.0 29973.2 32028.6 37486.6 39990.3 53184.0 49145.5 50839.3 43433.5 48652.6 36331.1 True False 35047.07076231531 35208.187738356704 38380.42271272216 37749.77314130189 42762.97698453849 46568.22346429182 46023.4334593422 42293.416646597216 49364.05223332369 42917.640833170626 0.8166122387423441 0.8203663354940199 0.894280812449931 0.8795863987035714 0.9963962639690903 1.0850601887767255 1.0723663408770396 0.9854553005604411 1.1502042347856802 1.0 15.38928315341113 -6.246228304803593 1.6239505792795645 1.0604531363472194 0.8358755899790481 0.8135787916817702 0.04687247570931425 0.15176414128971857 0.7941219109952057 0.01647278869281667 0.022504281348403675 5.672463305897412e-07 6.246228304803593 -0.2245775463681713 SPSLSLAPLS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 SPSLSLAPLSPR 12 0 G3V160;Q969H4-2;Q969H4 G3V160 CNKSR1 Connector enhancer of kinase suppressor of ras 1 1 SPSLSLAPLS(1)PR;SPSLSLAPLS(1)PR 164.92 8.5802e-05 20435900.0 43668.0 38037.0 40139.0 41948.0 64954.0 64207.0 45461.0 46865.0 60129.0 48336.0 True False 43045.28631226959 37948.92766348631 36838.926361020705 45032.99585442585 61133.5334244774 61461.01628382737 47814.74813761864 49042.518989093885 53356.63883355956 56690.813196328454 0.7592991506965611 0.6694017165014675 0.649821801522624 0.7943614373367709 1.0783675515954088 1.0841441993604681 0.8434302745319472 0.8650875904576033 0.9411866901393323 1.0 15.790827343465933 -6.039398349572502 5.1623440214382255 0.9608619259534399 0.6937536726445448 0.7211716421697374 0.07807957368816794 0.11670955420840676 7.7728310329040475 0.02574798556106479 0.03483762410976031 9.132751703319635e-07 6.039398349572502 -0.2671082533088951 SPSLSPS(ph)PPSPLEK ddPTM_PC-9_AZD4547_30min_R2 1 SPSLSPSPPSPLEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 SPS(0.001)LS(0.117)PS(0.844)PPS(0.037)PLEK 69.01 0.030693 9909000.0 14986.0 12091.0 13255.0 19806.0 15452.0 15922.0 12003.0 15916.0 15106.0 12534.0 True False 19751.23627183591 15999.179297608096 13079.230039336853 15240.032699649631 13306.756520934963 14926.394823002833 13071.243747107917 13456.54791329526 15904.47232048979 12095.188475052677 1.632982926440085 1.322772218937119 1.0813581008939086 1.260007872641543 1.1001694226081093 1.2340770756726736 1.0806978141819314 1.1125538011293086 1.314942082406907 1.0 13.56214563005003 -4.840609506937522 2.5920950288621145 1.1551183113392691 1.6994027229566402 0.7233199163646422 0.09178658674431313 0.20582263242992443 2.003824311606815 0.02222617798837744 0.2350531802273246 1.443412603296401e-05 4.840609506937522 0.5442844116173711 SPSLSPS(ph)PPSPLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSLSPSPPSPLEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 SPS(0.019)LS(0.063)PS(0.706)PPS(0.212)PLEK;S(0.072)PS(0.006)LS(0.347)PS(0.518)PPS(0.056)PLEK 170.42 5.9578e-19 0.0 30527.0 31689.0 28487.0 33855.0 33835.0 30085.0 30119.0 26895.0 26295.0 26461.0 True False 35694.6181642667 34834.87449469495 29166.23811754911 31958.214109390894 27205.27463657978 28507.289638384354 27265.910277323408 26189.034747608013 26679.514629747362 31258.16983483926 1.141929241310946 1.1144246345436777 0.9330756813868688 1.022395561808337 0.8703412509537821 0.9119948413170091 0.8722810843177958 0.8378300740569473 0.8535213280468938 1.0 14.931945690596665 -5.091432189377763 0.7390510237024327 0.879166936008427 1.256228123862789 0.7106837592366341 0.055713229392991455 0.9812259790935605 0.5449856697745394 0.022967052040836287 0.2859260069067134 8.101544290973614e-06 5.091432189377763 0.37706118785436205 SPSLSPS(ph)PPSPLEK ddPTM_PC-9_Lapatinib_30min_R1 3 SPSLSPSPPSPLEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.026)PS(0.012)LS(0.026)PS(0.472)PPS(0.464)PLEK;S(0.006)PS(0.027)LS(0.281)PS(0.67)PPS(0.017)PLEK;S(0.001)PS(0.003)LS(0.142)PS(0.548)PPS(0.306)PLEK 134.25 2.0991e-05 105303900.0 74850.0 69345.0 70720.0 64577.0 89312.0 70175.0 64345.0 64953.0 72564.0 60834.0 True False 73782.62527419101 69184.43591304401 64905.67458709451 69326.2080025569 84058.84375414801 67173.7788359149 67676.46925749691 67970.95350258429 64391.07818720451 71349.07584379015 1.0341076517336933 0.9696612758448988 0.9096918750454083 0.9716482965292772 1.1781350039933844 0.941480713541174 0.948526220657238 0.9526535935994205 0.902479498517692 1.0 16.122607122716282 SPSLSPSPPS(ph)PLEK ddPTM_PC-9_AZD4547_30min_R2 6 SPSLSPSPPSPLEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 SPSLSPS(0.06)PPS(0.94)PLEK;SPSLS(0.001)PS(0.046)PPS(0.953)PLEK;SPSLSPS(0.061)PPS(0.939)PLEK;SPSLS(0.001)PS(0.384)PPS(0.615)PLEK;S(0.002)PS(0.006)LS(0.004)PS(0.47)PPS(0.517)PLEK;SPSLS(0.01)PS(0.06)PPS(0.929)PLEK 178.47 7.3365e-05 1159311100.0 282597.0 270351.0 308061.0 355027.0 330879.0 324906.0 273858.0 333843.0 312157.0 313205.0 True False 372456.967617244 357736.6737480476 303975.9098565187 273181.01026247174 284942.16223727894 304589.5764578924 298230.83146675717 282255.23529895855 328656.981738854 302239.788282183 1.2323227518592075 1.1836187279685708 1.0057441860457987 0.9038552197747676 0.9427685344037023 1.0077745825229192 0.9867358403133776 0.933878484044708 1.0874047510647635 1.0 18.20533407067372 -5.244915548054739 3.4183891506152375 0.975816241620052 1.221342726215753 0.784431613480386 0.04744400158632525 0.09871518436785477 2.437376660226429 0.012573393919475774 0.03599354735294103 5.689635594836922e-06 5.244915548054739 0.24552648459570103 SPSLSPSPPS(ph)PLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 SPSLSPSPPSPLEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.001)PSLS(0.01)PS(0.015)PPS(0.974)PLEK;SPS(0.002)LS(0.001)PS(0.012)PPS(0.984)PLEK;SPSLS(0.003)PS(0.042)PPS(0.955)PLEK;SPSLS(0.001)PS(0.019)PPS(0.98)PLEK;SPSLSPSPPS(1)PLEK;SPSLSPS(0.002)PPS(0.998)PLEK;SPS(0.002)LS(0.009)PS(0.462)PPS(0.527)PLEK;SPSLSPS(0.001)PPS(0.999)PLEK 160.8 0.0001901 975822100.0 357592.0 378246.0 332530.0 406873.0 406337.0 366243.0 450070.0 363767.0 363142.0 343995.0 True False 418125.26283606206 415795.763139271 340458.77632704825 384077.2249100642 326718.1817645602 347036.5723460462 407436.11137537594 354218.5016929959 368452.26475283224 406358.5704370777 1.0289564272911191 1.0232238062360606 0.8378284625838015 0.9451682648084725 0.8040144973764018 0.8540156344500744 1.0026516997959196 0.8716895064179397 0.9067171005068907 1.0 18.63239379664592 -5.241526374428661 23.50044424810069 0.8979926866272413 1.0260902133559555 0.3839578796590235 0.062253158635404836 364.94281586909966 430684.9527734124 0.01543564000614553 0.04068993600234953 5.734210419920521e-06 5.241526374428661 0.12809752672871422 SPSLSPSPPS(ph)PLEK ddPTM_PC-9_Lapatinib_30min_R1 6 SPSLSPSPPSPLEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 SPSLSPS(0.145)PPS(0.855)PLEK;SPSLS(0.001)PS(0.013)PPS(0.985)PLEK;SPSLSPS(0.13)PPS(0.87)PLEK;SPSLSPSPPS(1)PLEK;SPSLS(0.012)PS(0.196)PPS(0.791)PLEK;SPSLSPS(0.002)PPS(0.998)PLEK 153.2 1.9363e-05 1015584100.0 213397.9 259307.0 267074.0 240182.0 296741.0 284750.0 279345.0 317694.0 305114.0 295163.0 True False 210354.80681361802 258706.59057327424 245116.20665545354 257845.78550366394 279287.2777952528 272571.9062846703 293808.1172544173 332455.2230389665 270748.8483271416 346181.5312700241 0.6076430653070852 0.7473148253292613 0.7080568560552734 0.7448282540022113 0.8067653891605405 0.7873669784887001 0.8487111261439445 0.9603493918907217 0.7821007877972426 1.0 18.401169233641994 -2.9431749531833034 0.12542416831603823 1.0699656702222204 1.7155520411261658e-13 0.7670622969981462 0.052843731069062004 28.001027259628945 0.34097868136998716 0.34859242982492705 5.058274949327193 0.0011397905366104875 2.9431749531833034 -1.0699656702220488 SPSLSPSPPS(ph)PLEKTPLGER ddPTM_PC-9_AZD4547_30min_R2 4 SPSLSPSPPSPLEKTPLGER 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 SPS(0.011)LS(0.218)PS(0.317)PPS(0.453)PLEKTPLGER;SPSLSPSPPS(0.999)PLEKT(0.001)PLGER;SPSLSPSPPS(0.998)PLEKT(0.002)PLGER;SPSLSPSPPS(0.98)PLEKT(0.02)PLGER 143.17 2.1402e-05 78834000.0 165963.0 57884.0 160729.0 625150.0 397237.0 150964.0 92238.0 118063.0 90127.0 190455.0 True False 218735.78175515172 76593.87101668575 158597.62844153715 481031.32597121934 342087.49935973604 141524.19721516155 100447.00331131733 99819.07616784224 94890.92922208278 183787.22841998993 1.1901576819870066 0.41675295761930586 0.8629415101636464 2.6173272762564777 1.8613235658464737 0.7700436990744044 0.5465396272355563 0.5431230288741068 0.5163086142484197 1.0 17.487676990055412 -6.9206350286987535 7.67737637645604 0.6196903927057815 1.3731049380742522 0.2883889569016278 0.562315257394351 0.35525877107888526 29.568279971506065 0.2250355205574954 0.19837213895572403 1.200507759030622e-07 6.9206350286987535 0.7534145453684706 SPSLSPSPPS(ph)PLEKTPLGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPSLSPSPPSPLEKTPLGER 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 SPSLS(0.003)PS(0.021)PPS(0.974)PLEKT(0.001)PLGER;SPS(0.001)LS(0.04)PS(0.006)PPS(0.947)PLEKT(0.006)PLGER;SPSLSPSPPS(1)PLEKTPLGER;SPS(0.001)LS(0.014)PS(0.106)PPS(0.877)PLEKT(0.001)PLGER 114.66 9.7431e-06 52706400.0 67298.0 17637.1 30222.6 96977.0 82935.0 164118.0 68723.0 152843.0 137151.0 93908.0 True False 78690.22220391185 19387.994728466776 30943.221403848765 91543.69309367621 66684.48210387911 155511.3631667729 62213.05992856666 148831.03320054477 139156.57391079978 110932.77702468094 0.7093505122151987 0.17477246354477566 0.2789366879093304 0.8252177178734925 0.6011251488732026 1.4018522508651692 0.5608176554953199 1.3416326282666846 1.2544225218470773 1.0 16.759326172347187 -6.295871645684053 1.283273924716287 1.1043890408957278 0.3761192721360546 0.5117878820806157 0.2853597858796997 0.34783282076011274 1.1680066220499625 0.11205350101140285 0.15516026846262862 5.059741789237399e-07 6.295871645684053 -0.7282697687596731 SPSLSPSPPS(ph)PLEKTPLGER ddPTM_PC-9_Lapatinib_30min_R1 4 SPSLSPSPPSPLEKTPLGER 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 SPSLSPSPPS(1)PLEKTPLGER;SPSLSPSPPS(1)PLEKTPLGER;SPSLSPS(0.01)PPS(0.989)PLEKT(0.001)PLGER;SPSLSPS(0.013)PPS(0.986)PLEKT(0.001)PLGER 119.28 6.3233e-06 54900000.0 409561.0 72080.0 93264.0 82635.0 69193.0 65594.0 45418.9 41231.7 96205.0 60908.7 True False 403720.5850357111 71913.10318858194 85596.19392945094 88712.25356227887 65123.20377867211 62788.69752708224 47770.468405615546 43147.47530572117 85369.37981643798 71436.68763925886 5.651446033926156 1.0066690599055892 1.1982105660006912 1.241830444466549 0.9116212681574964 0.8789418938928515 0.6687105741358972 0.6039960240542981 1.1950355291882577 1.0 16.12437756699063 -4.7613753399360235 8.064531384759833 0.9533040505215881 5.70751046040213 0.9794612122301554 0.2035000883876218 0.012680193482552364 7.484595729230478 0.05618891839787394 0.32852279037566956 1.73230620126629e-05 4.7613753399360235 4.754206409880542 SPSMAVPS(ph)PGWVASPK ddPTM_PC-9_AZD4547_30min_R2 1 SPSMAVPSPGWVASPK 16 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 SPS(0.001)MAVPS(0.99)PGWVAS(0.008)PK 71.888 0.015172 5235300.0 23838.0 19455.0 43845.0 51510.0 45152.0 39608.0 33599.0 48948.0 34135.0 37870.0 True False 31417.988138797806 25743.448286739345 43263.58665218591 39635.16532156682 38883.424180252114 37131.305498649424 36589.24591011239 41384.21131314253 35939.30641201635 36544.18282673088 0.8597261098370099 0.7044472278610879 1.1838706821634004 1.0845820663029024 1.0640113192464151 1.016066104821725 1.0012331123559437 1.1324431992188733 0.9834480793404939 1.0 15.157354153033546 -5.255687100162718 24.999237299875148 1.0605464113407101 0.7820866536809769 0.7170048754752161 0.06937587873095637 225.94383850965428 981937.9347499884 0.017215440299522718 0.043008283085111024 5.5502545284486296e-06 5.255687100162718 -0.2784597576597333 SPSMAVPS(ph)PGWVASPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSMAVPSPGWVASPK 16 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 S(0.001)PS(0.007)MAVPS(0.993)PGWVASPK 108.77 0.00066777 4637400.0 17785.0 19886.0 19122.0 22230.0 30238.0 22631.0 23807.0 23850.0 18918.0 19169.0 True False 20795.649230238265 21860.150658004466 19577.94100058883 20984.525170632394 24313.080965299236 21444.19052040141 21551.828612246034 23223.962771163828 19194.639960660235 22644.187958279486 0.9183658636182035 0.9653757820011227 0.8645901118936115 0.9267068975621948 1.0737007222380675 0.9470063823843453 0.9517598357668619 1.0256036919474676 0.8476629851344271 1.0 14.466853183474061 -6.027973491014145 24.775188020616174 0.9755444724402441 0.9168056416183687 0.1736692971367778 0.059632548457667696 1088.4385805627614 963992.7328162618 0.017064193814417098 0.022085333854644125 9.376192367032762e-07 6.027973491014145 -0.058738830821875365 SPSMAVPSPGWVAS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 SPSMAVPSPGWVASPK 16 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 SPSMAVPSPGWVAS(1)PK 157.83 7.7244e-15 0.0 17254.0 15034.0 12327.0 20779.0 17733.0 15080.0 17753.0 16785.0 15664.0 17285.0 True False 22740.413094505322 19893.446494106374 12163.535925681279 15988.722582349783 15271.079043860971 14137.045216108705 19332.982607881935 14191.263930928686 16491.967061310203 16679.857411144538 1.3633457729267795 1.192662862981952 0.7292350063828659 0.9585647040164158 0.9155401432663147 0.8475519225160241 1.1590616233304687 0.8508024727745506 0.9887354942429665 1.0 14.025819335411526 -5.04704775712309 5.421352633678504 0.9317089600152862 1.3286567859242755 0.6371773041411496 0.1081256729956833 0.1016282694595284 7.206490532032853 0.026782150701426137 0.08024675984313598 8.973301143129846e-06 5.04704775712309 0.39694782590898925 SPSMAVPSPGWVAS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSMAVPSPGWVASPK 16 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 SPSMAVPS(0.014)PGWVAS(0.985)PK 99.344 0.0016963000000000002 4297600.0 45721.0 41914.0 28643.0 42711.0 49299.0 36462.0 43820.0 53138.0 36420.0 38092.0 True False 53460.662269087625 46074.94492002408 29325.957749182406 40318.041140930305 39639.21484583262 34549.86853231745 39669.05237067342 51743.1838043649 36952.57360012928 44997.77806389392 1.1880733798272651 1.0239382232296148 0.6517201295482068 0.8960007110502503 0.880914937389742 0.7678127680717675 0.8815780262382276 1.149905307121897 0.82120885052722 1.0 15.457566144206343 -9.909953500981775 10.41536688093537 1.0000042986383293 0.9128037382841847 0.023322717259575576 0.1562665483587456 0.0 0.0 0.15549747160841468 0.0377136764681163 1.2304005002148236e-10 9.909953500981775 -0.08720056035414459 SPSMAVPSPGWVAS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 SPSMAVPSPGWVASPK 16 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 SPSMAVPS(0.007)PGWVAS(0.993)PK 131.18 7.6572e-05 0.0 14174.0 14799.0 13048.0 12985.0 15318.0 12338.0 12954.0 14066.0 13701.0 12484.0 True False 13971.87616080675 14764.73382474784 11975.243806736536 13939.96021669018 14417.025356346718 11810.332501282757 13624.694735591198 14719.557710457579 12157.849102073873 14641.842766115631 0.9542430132592786 1.0083931415324718 0.8178781863748614 0.9520632368044712 0.9846455522463887 0.8066151706405701 0.9305314196599398 1.0053077297429935 0.8303496558650217 1.0 13.837809516657204 -10.727313825132233 3.7858088076268843 1.0000726932043478 0.922809286992654 0.09530744298667826 0.0727449029031259 25510408.119346745 36510073.86961682 18312.68457011972 0.017685231372414466 1.8736401094365787e-11 10.727313825132233 -0.07726340621169381 SPSMPS(ph)LNQTWPELNQSSEDTAIVHPVPIR ddPTM_PC-9_AZD4547_30min_R2 1 SPSMPSLNQTWPELNQSSEDTAIVHPVPIR 30 0 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2 H0YDT0 REPS1 RalBP1-associated Eps domain-containing protein 1 1 S(0.083)PS(0.358)MPS(0.454)LNQT(0.105)WPELNQSSEDTAIVHPVPIR 107.09 3.1543000000000004e-15 4598000.0 0.0 1310.3 1201.5 1551.3 1432.4 1202.9 726.21 687.13 0.0 1511.7 True False 0.0 1733.8288506869485 1185.5673249538465 1193.67175234608 1233.5359850237676 1127.6824728419867 790.8412831448172 580.9498471765878 0.0 1458.7758431256702 0.0 1.1885505637191875 0.8127138453386855 0.8182694812031158 0.8455966630080131 0.7730334157616288 0.5421266652252125 0.3982447679773789 0.0 1.0 10.510542499065313 -7.432101208822625 2.9493646987743043 0.4044113121686999 0.772346146915411 0.09811196546750534 0.3602853493910288 0.474762185509084 7.9881730474002834 0.16755992968826347 0.10119937727439698 3.697420043505004e-08 7.432101208822625 0.3679348347467111 SPSPGGPQLS(ph)PQLPR ddPTM_PC-9_AZD4547_30min_R2 3 SPSPGGPQLSPQLPR 15 0 Q9HCH0;H7C1V4;Q9HCH0-2 Q9HCH0 NCKAP5L Nck-associated protein 5-like 1 SPS(0.011)PGGPQLS(0.989)PQLPR;SPS(0.001)PGGPQLS(0.999)PQLPR;SPSPGGPQLS(1)PQLPR 129.88 1.391e-05 19005400.0 16169.1 17464.9 30002.7 52917.3 50789.0 44284.9 44831.4 58809.0 51356.7 41988.7 True False 21310.537461827174 23110.087380265973 29604.844594584058 40718.03404913508 43737.82403195481 41515.75820231114 48821.3077500703 49721.420346379804 54071.31031521897 40518.68839336559 0.5259434178850789 0.5703562552644214 0.7306466662289953 1.0049198447352043 1.0794481698750227 1.0246076526284795 1.2049083937787126 1.227123145341522 1.3344782977741314 1.0 15.306299853811572 -5.645740332706911 0.8312804788608706 1.1943120540218253 0.4218498687144371 0.8808409672122787 0.09037298659505917 0.2880018256296986 0.33223333533209665 0.039881683125056536 0.16400112519973142 2.260787104456121e-06 5.645740332706911 -0.7724621853073882 SPSPGGPQLS(ph)PQLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPSPGGPQLSPQLPR 15 0 Q9HCH0;H7C1V4;Q9HCH0-2 Q9HCH0 NCKAP5L Nck-associated protein 5-like 1 SPSPGGPQLS(1)PQLPR;SPS(0.018)PGGPQLS(0.981)PQLPR;S(0.001)PS(0.032)PGGPQLS(0.967)PQLPR;SPSPGGPQLS(1)PQLPR 153.48 2.0621999999999997e-05 20805500.0 18169.7 19630.6 29588.699999999997 31504.100000000002 40074.4 32484.100000000002 31440.3 31081.100000000002 41126.5 24888.699999999997 True False 21245.471342066925 21579.396233884258 30294.20682376961 29739.027414670272 32222.10899648745 30780.5766110102 28462.047175939828 30265.25405814758 41727.89725880606 29400.824291159217 0.7226148196278771 0.7339724907091516 1.0303863090287244 1.0115031850863023 1.095959374383139 1.046929035260616 0.9680697008382286 1.029401548692235 1.419276440876985 1.0 14.843568983049765 -5.291757881303764 2.9436086521546763 1.0756270572610316 0.7120693975776853 0.5751962643985864 0.11974099888109237 0.18797294985876933 3.2275375892147853 0.0324811607385753 0.09218130215172596 5.10789685300193e-06 5.291757881303764 -0.3635576596833463 SPSPGGPQLS(ph)PQLPR ddPTM_PC-9_Lapatinib_30min_R1 3 SPSPGGPQLSPQLPR 15 0 Q9HCH0;H7C1V4;Q9HCH0-2 Q9HCH0 NCKAP5L Nck-associated protein 5-like 1 SPSPGGPQLS(1)PQLPR;S(0.005)PS(0.002)PGGPQLS(0.993)PQLPR;SPSPGGPQLS(0.999)PQLPR 165.24 0.00028577 16483000.0 26082.0 20551.7 25219.5 22734.6 22292.1 21908.9 20762.3 19234.7 29326.2 16158.9 True False 25710.065897146997 20504.11380134268 23146.050060085254 24406.578324402355 20980.922505954866 20971.907419140363 21837.270303285877 20128.414381724615 26023.174537423474 18951.94433461918 1.3565925185936134 1.0819002757352014 1.221302134040399 1.287813951617581 1.107059103568038 1.1065834221996607 1.1522443247892051 1.0620764828311784 1.3731137068552595 1.0 14.21005824578314 -6.275721476718572 24.583866593529926 1.1362067661424815 1.2247163643489454 0.16795025832248212 0.11132723680054991 1352.2467395240526 2327625.9405820225 0.03310632767715861 0.037713185632773226 5.300032384823988e-07 6.275721476718572 0.08850959820646387 SPSPISNQPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 SPSPISNQPSPR 12 0 F6SS63;Q8N5C8-2;Q8N5C8 F6SS63 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 1 S(0.021)PS(0.005)PIS(0.079)NQPS(0.895)PR 72.243 0.025491999999999997 18630000.0 3342.0 7512.3 11514.0 15042.0 12535.0 8977.4 8307.7 12903.0 12496.0 14153.0 True False 4404.686482081647 9940.504063966693 11361.31683688605 11574.299296583345 10794.731619849837 8416.041758825882 9047.069205852573 10909.13783144312 13156.513048910389 13657.507777837936 0.32251026715350956 0.7278417282029426 0.8318733565227823 0.8474678898125896 0.7903880997502684 0.6162209017726213 0.6624246057932524 0.7987648997824771 0.9633172657063749 1.0 13.737406624188507 -3.6347202649203356 0.11674791460722647 1.0825215985914098 3.6261269559268037e-20 0.4318499439339153 0.13829991916228815 74.07601436319736 1.0076463323329727 1.4460957376344947 12.69469743824387 0.00023188877967257772 3.6347202649203356 -1.0825215985914098 SPSPPDGS(ph)PAATPEIR ddPTM_PC-9_AZD4547_30min_R2 3 SPSPPDGSPAATPEIR 16 0 O00499-6;O00499-11;O00499-2;O00499;O00499-7;O00499-8;O00499-4;O00499-3;O00499-5;O00499-9;O00499-10 O00499-6;O00499-9 BIN1 Myc box-dependent-interacting protein 1 1 SPS(0.011)PPDGS(0.987)PAAT(0.002)PEIR;SPS(0.004)PPDGS(0.996)PAATPEIR;SPS(0.004)PPDGS(0.996)PAATPEIR 221.34 1.0916000000000002e-22 153208000.0 95824.5 96051.8 158658.4 207619.0 182515.0 158874.7 121637.2 157782.3 116094.8 144378.8 True False 126294.69772658097 127098.6659546766 156554.48595044322 159755.64723157414 157175.9426882244 148940.23989361455 132462.67515752022 133400.6710115559 122231.33411576829 139324.14215748667 0.9064810719151767 0.9122515594677708 1.1236709124932565 1.1466472698679349 1.1281314225538797 1.0690196084269317 0.9507517728534765 0.9574842446240573 0.8773162513184734 1.0 17.088085744960672 -7.287609519805522 7.84412214219262 0.9425307976745048 1.0531621173392267 0.26180174865625017 0.08294415517317688 0.3731911193956248 96.04363354733343 0.03890457216030888 0.02666584592330097 5.1569210212418497e-08 7.287609519805522 0.11063131966472195 SPSPPDGS(ph)PAATPEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SPSPPDGSPAATPEIR 16 0 O00499-6;O00499-11;O00499-2;O00499;O00499-7;O00499-8;O00499-4;O00499-3;O00499-5;O00499-9;O00499-10 O00499-6;O00499-9 BIN1 Myc box-dependent-interacting protein 1 1 SPS(0.112)PPDGS(0.888)PAATPEIR;SPSPPDGS(1)PAATPEIR;SPSPPDGS(1)PAATPEIR 223.68 1.5084e-28 113658000.0 94950.0 86474.0 112965.0 118701.0 120988.0 111891.0 107646.0 95259.0 88039.0 77444.0 True False 111023.15965201681 95058.5672332435 115658.51402214837 112050.56780383422 97281.2699196249 106023.23898715201 97448.99159045001 92758.55218525339 89326.40382157543 91483.9841536332 1.2135802859828513 1.0390733210045526 1.2642487654223475 1.2248107561172963 1.0633694063460994 1.1589267779276249 1.0652027509733235 1.0139321438983215 0.9764157589766265 1.0 16.481231576448195 -7.4326901152699 1.0929028031469117 0.9814315185226193 1.1695512971755306 0.5744673511166605 0.06452299188548342 0.39185832791401376 0.8814105238271762 0.04956114842929916 0.02451623736777954 3.692409713069769e-08 7.4326901152699 0.1881197786529113 SPSPPDGS(ph)PAATPEIR ddPTM_PC-9_Lapatinib_30min_R1 4 SPSPPDGSPAATPEIR 16 0 O00499-6;O00499-11;O00499-2;O00499;O00499-7;O00499-8;O00499-4;O00499-3;O00499-5;O00499-9;O00499-10 O00499-6;O00499-9 BIN1 Myc box-dependent-interacting protein 1 1 SPS(0.001)PPDGS(0.994)PAAT(0.005)PEIR;SPS(0.002)PPDGS(0.997)PAATPEIR;SPS(0.001)PPDGS(0.999)PAATPEIR;SPS(0.003)PPDGS(0.997)PAATPEIR 194.05 9.8513e-12 161359000.0 148060.9 124734.7 156262.4 142738.6 137505.1 135951.5 102717.9 113271.6 135933.1 106339.5 True False 145949.52441495634 124445.88446582726 143415.1086623078 153236.0728060114 129417.32036342807 130137.17126342539 108036.13025945534 118534.6120543059 120622.88283899834 124720.14088652274 1.1702161605778594 0.9978010254098011 1.1498953388193713 1.2286393498018418 1.0376617556997396 1.0434334850682325 0.8662284174113671 0.9504047318400258 0.9671483850290683 1.0 16.928334937285058 -6.815099954002259 2.1982449312304353 0.9442423839464473 1.1251436809725788 0.5879786666073884 0.0677897320423949 0.22003017995409307 2.1814953305550326 0.02741468417879305 0.024394341680685327 1.5307351184765592e-07 6.815099954002259 0.18090129702613145 SPSPPT(ph)QHTGQPPGQPSAPSQLSAPR ddPTM_PC-9_AZD4547_30min_R2 1 SPSPPTQHTGQPPGQPSAPSQLSAPR 26 0 Q68EM7-6;Q68EM7-5;Q68EM7;Q68EM7-7;Q68EM7-3;Q68EM7-2;I3L460 Q68EM7-6 ARHGAP17 Rho GTPase-activating protein 17 1 S(0.032)PS(0.032)PPT(0.48)QHT(0.455)GQPPGQPSAPSQLSAPR 90.77799999999999 9.920200000000001e-07 201980000.0 1557.6 3178.3 4967.2 5108.9 5677.3 5565.0 1851.5 5777.9 2766.3 4513.3 True False 2052.884399907352 4205.623319955984 4901.331682489175 3931.1220367181672 4889.104892331352 5217.0196702682315 2016.2799131692339 4885.058317933445 2912.5209704866206 4355.290740741604 0.47135415799079206 0.9656354926238206 1.1253741654121105 0.9026084068152909 1.1225668235179294 1.1978579573266088 0.4629495556537538 1.1216377065797527 0.6687316975744968 1.0 12.088553314904235 -10.60015256084781 14.519112508357672 0.999999999696319 0.912199352894498 0.010308143350160281 0.2595297686821941 0.0 0.0 0.2438026236231588 0.059130821705940674 2.5110042001236518e-11 10.60015256084781 -0.08780064680182098 SPSPPT(ph)QHTGQPPGQPSAPSQLSAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSPPTQHTGQPPGQPSAPSQLSAPR 26 0 Q68EM7-6;Q68EM7-5;Q68EM7;Q68EM7-7;Q68EM7-3;Q68EM7-2;I3L460 Q68EM7-6 ARHGAP17 Rho GTPase-activating protein 17 1 S(0.124)PS(0.106)PPT(0.735)QHT(0.035)GQPPGQPSAPSQLSAPR;S(0.073)PS(0.073)PPT(0.795)QHT(0.059)GQPPGQPSAPSQLSAPR 81.525 4.825e-05 196296000.0 2764.5 4230.1 3488.2 3559.75 7710.7 5160.2 3769.4700000000003 3141.8 3352.3 2810.5 True False 3232.4752486361367 4650.036372243019 3571.3719170721665 3360.3087483652134 6199.8436867230885 4889.59002798707 3412.398513000507 3059.331079012263 3401.3210455714798 3320.0214020942394 0.9736308466557235 1.4006043362581393 1.0757074983972625 1.012134664627632 1.8674107591030236 1.472758586707532 1.0278242516292206 0.9214793245255783 1.0244876865630919 1.0 11.696976826413716 -7.389218051109059 6.275015028883376 0.979442855449906 1.3065997025634584 0.2717924160446219 0.24659747386169178 0.3471119011357968 16.231027416484476 0.1115876672736763 0.07450142124082854 4.081144282887499e-08 7.389218051109059 0.3271568471135524 SPSPPT(ph)QHTGQPPGQPSAPSQLSAPR ddPTM_PC-9_Lapatinib_30min_R1 4 SPSPPTQHTGQPPGQPSAPSQLSAPR 26 0 Q68EM7-6;Q68EM7-5;Q68EM7;Q68EM7-7;Q68EM7-3;Q68EM7-2;I3L460 Q68EM7-6 ARHGAP17 Rho GTPase-activating protein 17 1 S(0.309)PS(0.309)PPT(0.382)QHTGQPPGQPSAPSQLSAPR;S(0.024)PS(0.024)PPT(0.943)QHT(0.008)GQPPGQPSAPSQLSAPR;S(0.118)PS(0.118)PPT(0.577)QHT(0.188)GQPPGQPSAPSQLSAPR;S(0.01)PS(0.033)PPT(0.708)QHT(0.249)GQPPGQPSAPSQLSAPR 117.49 1.8442e-11 283806900.0 345416.4 248305.8 288097.1 281030.1 261443.5 325062.8 287772.7 282756.0 270110.5 219552.7 True False 340490.69879439013 247730.86317596343 264410.86852496676 301697.991042931 246065.9073476975 311160.62180239696 302672.1623233651 295893.87601152714 239687.81110033754 257502.0916594162 1.322283235061012 0.962053789852796 1.0268299834810213 1.1716331665451878 0.9555879944973623 1.2083809486641062 1.175416325253361 1.1490930970878854 0.9308188898805504 1.0 17.974224625623584 -8.261605922529519 24.999999292107788 0.965409433407157 1.1137912624972957 0.24460673518753884 0.10900159760117577 22.097939076565883 3315785.5623883978 0.08406187777294553 0.02697321072599369 5.4751254875404776e-09 8.261605922529519 0.14838182909013864 SPSPPTQHT(ph)GQPPGQPSAPSQLSAPR ddPTM_PC-9_AZD4547_30min_R2 3 SPSPPTQHTGQPPGQPSAPSQLSAPR 26 0 Q68EM7-6;Q68EM7-5;Q68EM7;Q68EM7-7;Q68EM7-3;Q68EM7-2;I3L460 Q68EM7-6 ARHGAP17 Rho GTPase-activating protein 17 1 S(0.001)PS(0.002)PPT(0.13)QHT(0.867)GQPPGQPSAPSQLSAPR;S(0.251)PS(0.251)PPT(0.208)QHT(0.29)GQPPGQPSAPSQLSAPR;S(0.002)PS(0.009)PPT(0.131)QHT(0.858)GQPPGQPSAPSQLSAPR 91.48100000000001 7.6785e-07 303190000.0 52386.5 65148.0 72285.9 109699.0 118045.3 87379.1 76336.5 103950.1 87302.7 91134.40000000001 True False 69044.31729310901 86205.81696142354 71327.34173523201 84409.59038265496 101656.74770519811 81915.27106385179 83130.3006166046 87887.00058066307 91917.34249000553 87943.81239515266 0.7850957948340506 0.9802374335795235 0.8110558297693661 0.9598127268281526 1.155928369905434 0.9314500796916423 0.9452660551384808 0.9993539987300718 1.0451825999650644 1.0 16.42429445479233 -5.97441690992892 9.644165707890235 1.0101307413594656 0.8731073029635936 0.4545499665871512 0.07495147491008028 0.318613361172787 113.17721280853955 0.020935099527772665 0.030893297979261377 1.0606768497338177e-06 5.97441690992892 -0.13702343839587194 SPSPPTQHT(ph)GQPPGQPSAPSQLSAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSPPTQHTGQPPGQPSAPSQLSAPR 26 0 Q68EM7-6;Q68EM7-5;Q68EM7;Q68EM7-7;Q68EM7-3;Q68EM7-2;I3L460 Q68EM7-6 ARHGAP17 Rho GTPase-activating protein 17 1 S(0.014)PS(0.021)PPT(0.307)QHT(0.658)GQPPGQPSAPSQLSAPR;SPS(0.001)PPT(0.019)QHT(0.979)GQPPGQPSAPSQLSAPR 101.2 4.574e-09 122881800.0 2040.83 6250.299999999999 11892.3 12585.6 5687.1 11929.2 9745.5 7977.0 5925.299999999999 3336.5 True False 2386.3022107701518 6870.7884772063435 12175.857533798899 11880.469635065725 4572.753580188944 11303.611751843597 8822.335688690036 7767.612202330141 6011.946302933713 3941.381038280532 0.6054482394859242 1.743243906253681 3.0892363401410035 3.014291061858029 1.1601906884354056 2.867931733079762 2.238386901191079 1.970784384175868 1.5253400380584585 1.0 11.944485515351815 -8.44128595355466 1.9568003231834494 1.010903596255253 2.152590715094305 0.17536389393456486 0.7546395396279821 0.558299789773581 4.6041106099338975 0.7411344746776123 0.20979071941931132 3.6200456439763074e-09 8.44128595355466 1.141687118839052 SPSPPTQHT(ph)GQPPGQPSAPSQLSAPR ddPTM_PC-9_Lapatinib_30min_R1 2 SPSPPTQHTGQPPGQPSAPSQLSAPR 26 0 Q68EM7-6;Q68EM7-5;Q68EM7;Q68EM7-7;Q68EM7-3;Q68EM7-2;I3L460 Q68EM7-6 ARHGAP17 Rho GTPase-activating protein 17 1 S(0.001)PS(0.002)PPT(0.03)QHT(0.967)GQPPGQPSAPSQLSAPR;S(0.069)PS(0.069)PPT(0.351)QHT(0.51)GQPPGQPSAPSQLSAPR 104.45 2.2083000000000003e-09 146436500.0 7743.2 9202.2 11120.8 9162.0 9753.5 7255.799999999999 8194.3 5518.1 12601.8 10808.900000000001 True False 7632.780548071029 9180.89287128148 10206.490751529407 9835.804043536036 9179.8183061188 6945.486348095917 8618.560758982172 5774.49107081445 11182.452581163014 12677.20396304607 0.6020870667002372 0.7242048718348065 0.8051058246977197 0.7758654094552169 0.7241201082571428 0.5478720992690458 0.6798471322308292 0.4555019456693319 0.8820913991570821 1.0 13.62994896465942 -10.766705587635569 4.070741796265934 1.0002611853085606 0.6853707341914455 0.3789630140477471 0.11956028450747462 57327535.84977787 64.60559789871118 141209.5037044172 0.028864719821626736 1.7111749437716064e-11 10.766705587635569 -0.3148904511171151 SPSPSPT(ph)SPGSLRK ddPTM_PC-9_AZD4547_30min_R2 1 SPSPSPTSPGSLRK 14 1 Q5VZY9;O15075-2;O15075;O15075-3;O15075-4 Q5VZY9 DCLK1 Serine/threonine-protein kinase DCLK1 1 S(0.045)PS(0.004)PS(0.038)PT(0.456)S(0.456)PGS(0.001)LRK 127.57 9.6762e-05 8580500.0 15718.0 12968.0 18686.0 30639.0 26172.0 21367.0 15367.0 21177.0 12585.0 19042.0 True False 20715.997045290045 17159.65239693836 18438.211430784486 23575.651917831216 22538.46956160431 20030.918112241015 16734.6332301764 17904.581249048366 13250.217407213286 18375.34537593371 1.1273800095437607 0.9338410813987992 1.0034212175915405 1.2830045604861597 1.2265603231122428 1.09009750306384 0.9107112213571693 0.9743806651110947 0.7210867135355816 1.0 14.165483746095138 -7.257298809503281 4.131647371195999 0.8962201833326088 1.112591429094507 0.4411194987383882 0.11563601179437724 0.22599097934264264 9.43634133777667 0.05227967494926475 0.036996874015537494 5.529695163018215e-08 7.257298809503281 0.21637124576189815 SPSPSPT(ph)SPGSLRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPSPSPTSPGSLRK 14 1 Q5VZY9;O15075-2;O15075;O15075-3;O15075-4 Q5VZY9 DCLK1 Serine/threonine-protein kinase DCLK1 1 S(0.001)PS(0.001)PS(0.012)PT(0.477)S(0.477)PGS(0.033)LRK;SPSPS(0.006)PT(0.494)S(0.494)PGS(0.005)LRK 122.12 0.00021282 14062200.0 31162.9 25801.8 30920.0 39102.0 39083.0 39802.0 33535.0 37314.0 38391.0 26952.3 True False 36438.16347466922 28363.23218584428 31657.250064753 36911.24171039444 31424.966709662993 37714.71305258348 30358.3220276251 36334.547037451026 38952.395746363625 31838.5386357106 1.1444672097418318 0.8908459182241373 0.9943060021368486 1.1593258765022028 0.9870103357826939 1.1845616874601799 0.9535086511029353 1.141212775284153 1.2234354155524592 1.0 14.958486498364515 -5.732448497195638 24.453059999635844 1.0922274056829273 0.9979702018793278 0.11813796496218976 0.10218256814621023 314.2481737706817 265057.0523083784 0.02661001008621589 0.04607897401283654 1.851618463859348e-06 5.732448497195638 -0.09425720380359948 SPSPSPTS(ph)PGSLRK ddPTM_PC-9_AZD4547_30min_R2 1 SPSPSPTSPGSLRK 14 1 Q5VZY9;O15075-2;O15075;O15075-3;O15075-4 Q5VZY9 DCLK1 Serine/threonine-protein kinase DCLK1 1 S(0.015)PS(0.022)PS(0.094)PT(0.209)S(0.651)PGS(0.009)LRK 97.2 0.0040553 7972100.0 14821.0 11203.0 23235.0 33159.0 26655.0 23575.0 17134.0 23416.0 18374.0 21480.0 True False 19533.76970404911 14824.150663394545 22926.888718520688 25514.704851443104 22954.41334879118 22100.851523193804 18658.89280704383 19797.595246149907 19345.212128735562 20727.991738003147 0.9423860232554742 0.7151754425015341 1.1060834550838823 1.2309299026139562 1.1074113517088133 1.0662321657854401 0.90017851429544 0.9551140070097852 0.9332892628120665 1.0 14.33929272513454 -10.607961956964793 14.559829632603604 0.9999998923051078 0.9985742626875383 0.0 0.13463845346735906 0.0 0.0 0.14437807477964829 0.03501682660822443 2.466255365147094e-11 10.607961956964793 -0.0014256296175694239 SPSPT(ph)LGESLAPHK ddPTM_PC-9_AZD4547_30min_R2 1 SPSPTLGESLAPHK 14 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 S(0.059)PS(0.213)PT(0.728)LGESLAPHK 148.89 0.00045877 5482500.0 11993.0 10279.0 28008.0 51723.0 42189.0 29452.0 19079.0 36309.0 26748.0 35099.0 True False 15806.524530103286 13601.485733199379 27636.595619897907 39799.06146238402 36331.785585149206 27610.361784140154 20776.994039079564 30698.278347815867 28161.844672875737 33870.19469330414 0.4666794706446759 0.4015768393527505 0.8159562078148147 1.1750467283334505 1.0726771993528488 0.8151816673672235 0.6134300150092437 0.9063508086029592 0.8314639147451698 1.0 15.047728659332718 -5.326878114582703 4.578448122095425 0.9073442526609916 0.43218984299837154 0.6270929675161847 0.14598287102089963 0.1414029987476452 5.867658663224694 0.043205861826259684 0.09718463691478454 4.711095254612971e-06 5.326878114582703 -0.47515440966262007 SPSQPGQSGLCGVAAAATGHT(ph)PPLAEAPK ddPTM_PC-9_Lapatinib_30min_R1 2 SPSQPGQSGLCGVAAAATGHTPPLAEAPK 29 0 Q6AWC2-2;Q6AWC2-4;Q6AWC2;Q6AWC2-6;Q6AWC2-5;Q6AWC2-3 Q6AWC2-2 WWC2 Protein WWC2 1 SPSQPGQSGLCGVAAAAT(0.219)GHT(0.781)PPLAEAPK;SPSQPGQSGLCGVAAAAT(0.083)GHT(0.917)PPLAEAPK 122.22 2.0655e-13 9245800.0 26450.0 24165.0 26768.0 26435.0 29620.0 23779.0 20456.9 23800.0 25182.0 27980.0 True False 26072.818149664043 24109.04742719319 24567.238367468115 28379.118084574886 27877.809835160588 22762.027601556387 21516.058185619553 24905.83488617166 22345.737981784132 32816.30571899353 0.7945080221072396 0.7346667121411925 0.748629007111212 0.8647871069822929 0.8495109130771347 0.6936194401791579 0.6556514426048395 0.7589469423962789 0.6809339897406792 1.0 15.002125216790109 -6.767918066129669 24.99703149083788 0.7363783721959865 0.7957993398402113 0.018422107050147796 0.09748492697290473 426.18209537667735 1644348.8295665535 0.03277193467069342 0.029580269384662634 1.7064042883729666e-07 6.767918066129669 0.05942096764422489 SPSQSS(ph)LPAVVVETFPATVNGTVEGGSGAGR ddPTM_PC-9_AZD4547_30min_R2 2 SPSQSSLPAVVVETFPATVNGTVEGGSGAGR 31 0 O00499-9;O00499-10 O00499-9 BIN1 Myc box-dependent-interacting protein 1 1 S(0.072)PS(0.245)QS(0.187)S(0.496)LPAVVVETFPATVNGTVEGGSGAGR;S(0.123)PS(0.123)QS(0.142)S(0.613)LPAVVVETFPATVNGTVEGGSGAGR 108.95 1.1845999999999998e-15 5726600.0 15062.0 16463.4 26123.5 27843.3 34771.0 33135.3 27176.0 34556.0 24820.0 28137.3 True False 19851.402690937684 21784.872090665875 25777.085321208335 21424.457359696804 29943.646841148704 31063.344452873123 29594.61135311211 29216.164217883306 26131.934528965725 27152.221691327584 0.7311152257304314 0.8023237412511242 0.9493545542699193 0.7890498834038238 1.1028065099627815 1.144044299800143 1.089951742791074 1.0760137623366173 0.9624234372435262 1.0 14.72878262884707 -6.2623110272557065 24.999682768073004 1.0717864587310837 0.826229172669312 0.7413849809105706 0.07057276695630679 41.748143209323274 1197373.012687446 0.02224734136306883 0.026739837787508283 5.466243485120004e-07 6.2623110272557065 -0.24555728606177174 SPSQSS(ph)LPAVVVETFPATVNGTVEGGSGAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSQSSLPAVVVETFPATVNGTVEGGSGAGR 31 0 O00499-9;O00499-10 O00499-9 BIN1 Myc box-dependent-interacting protein 1 1 S(0.173)PS(0.173)QS(0.173)S(0.48)LPAVVVETFPATVNGTVEGGSGAGR 96.28399999999999 1.1688e-12 2145700.0 4262.6 6036.7 7199.4 8835.5 9920.7 8544.4 8578.1 5520.8 8755.4 5602.2 True False 4984.173989812402 6635.98368083956 7371.060999876548 8340.475580077486 7976.810051340834 8096.316622443456 7765.520267934127 5375.884849771123 8883.431161410532 6617.8345130092 0.7531427357415206 1.002742463232449 1.1138176673029025 1.2603028322454957 1.2053504867279756 1.2234087459467122 1.173423157177598 0.8123329223786605 1.3423471294042892 1.0 12.692143500421633 -4.815366073848891 1.978652731644533 1.1457576757270922 0.6545891953039995 0.4215166245010832 0.1397443910041763 0.6789426606240972 3.081181498745373 0.03745571291682994 0.6015800785170758 1.529797427048187e-05 4.815366073848891 -0.4911684804230927 SPSS(ph)DSWTCADTSTERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSSDSWTCADTSTERR 17 1 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHH7;H0YIQ0 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 S(0.248)PS(0.149)S(0.506)DS(0.097)WTCADTSTERR 64.04 0.010761 4509400.0 6780.8 10289.0 8437.6 8110.4 16202.0 11780.0 8562.9 10566.0 9451.6 7253.4 True False 7928.655513095286 11310.423922367887 8638.784383776188 7656.000582271575 13027.334407030172 11162.236062495196 7751.7601219725975 10288.653695602388 9589.81176932954 8568.384002117195 0.9253384898641522 1.3200183277935666 1.0082162962866275 0.8935174451074817 1.520395725006162 1.3027236010590886 0.9046933610885303 1.2007694441635817 1.119208915818894 1.0 13.06480742225912 -4.719233883551038 22.440061856013845 1.144966978399231 0.9253299185704139 0.10366938331961528 0.18998125039734667 5986.856680739755 3182351.7196573582 0.04802380586270516 15.069330405633325 1.908825009245585e-05 4.719233883551038 -0.21963705982881698 SPSS(ph)PQQQQQVLNILK ddPTM_PC-9_AZD4547_30min_R2 1 SPSSPQQQQQVLNILK 16 0 Q92793;Q92793-2 Q92793 CREBBP CREB-binding protein 1 S(0.033)PS(0.161)S(0.805)PQQQQQVLNILK 111.07 0.00049984 5531900.0 15083.0 13236.0 21049.0 26868.0 24564.0 18079.0 16165.0 30114.0 19649.0 16573.0 True False 19879.080254110562 17514.278155912725 20769.876506827728 20673.997706462007 21153.712605503915 16948.51727201786 17603.653684245557 25460.573250877955 20687.60602577147 15992.784314428602 1.2430030858463943 1.095136269680786 1.298702971194907 1.292707842486817 1.322703551152075 1.0597602605524419 1.100724760501124 1.592003790603714 1.2935587461845044 1.0 13.965133510796038 SPSS(ph)PQQQQQVLNILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSSPQQQQQVLNILK 16 0 Q92793;Q92793-2 Q92793 CREBBP CREB-binding protein 1 S(0.001)PS(0.017)S(0.982)PQQQQQVLNILK 163.9 6.2357e-05 4261700.0 20679.0 21063.0 33715.0 27311.0 30626.0 27996.0 26017.0 22427.0 18538.0 16367.0 True False 24179.546271132815 23153.995439482456 34518.893464849534 25780.85321345667 24625.05515058054 26527.840475858677 23552.481413231617 21838.315013370713 18809.08317954959 19334.207538899293 1.250609636960035 1.197566302776981 1.7853792763628684 1.3334321130869784 1.2736521577642308 1.3720676382771944 1.218176714294879 1.1295169439674888 0.972839623331177 1.0 14.238868012698907 -7.708842205338311 1.148217103115854 0.9753691389492091 1.3853703420537846 0.505717837450687 0.15185561896761818 0.43401923761643063 1.0413578785670634 0.13326549716545882 0.05411828430809593 1.955049665958567e-08 7.708842205338311 0.41000120310457555 SPSS(ph)PQQQQQVLNILK ddPTM_PC-9_Lapatinib_30min_R1 2 SPSSPQQQQQVLNILK 16 0 Q92793;Q92793-2 Q92793 CREBBP CREB-binding protein 1 S(0.079)PS(0.052)S(0.868)PQQQQQVLNILK;S(0.046)PS(0.046)S(0.909)PQQQQQVLNILK 153.48 9.237799999999999e-11 0.0 23177.0 27218.0 32838.0 25708.0 25919.0 22284.0 21336.3 21337.0 25432.0 16928.6 True False 22846.49172985875 27154.978393268928 30138.186398345686 27598.65207937398 24394.49537871463 21330.965266541174 22440.989214682297 22328.3949145481 22567.58034916742 19854.6859540584 1.1506851220272667 1.3676861198460966 1.5179382070349636 1.3900321638546327 1.2286517870471916 1.07435420111397 1.1302616050744052 1.124590686864229 1.136637487059043 1.0 14.27719192116702 -6.502637442660979 3.2699416059758724 1.1040438064990161 1.3674772292857293 0.6430025758417814 0.09207203365556868 0.16659984709370546 3.6754006932841263 0.03252649137186257 0.03506535754776261 3.1431315452444497e-07 6.502637442660979 0.2634334227867132 SPSSES(ph)SPQHPTPPARPR ddPTM_PC-9_AZD4547_30min_R2 1 SPSSESSPQHPTPPARPR 18 1 O14733;O14733-4;O14733-3;O14733-2 O14733 MAP2K7 Dual specificity mitogen-activated protein kinase kinase 7 1 S(0.037)PS(0.191)S(0.191)ES(0.24)S(0.191)PQHPT(0.149)PPARPR 87.554 0.0007693999999999999 7209400.0 2654.2 3922.4 9627.8 17645.0 12685.0 8264.6 4746.1 12696.0 8207.0 9817.1 True False 3498.1803892103844 5190.239093287404 9500.129081307228 13577.217862532458 10923.906709038318 7747.813255507424 5168.493705586014 10734.124925056336 8640.805265077433 9473.406317092677 0.3692632060865676 0.547874641872244 1.0028208189662822 1.4331928145038344 1.153112865995047 0.8178487226424777 0.54557922806083 1.133079756717388 0.9121117553553046 1.0 13.209667548071415 -5.174370425001109 3.6944223947779515 1.0035217383535002 0.4107330109629068 0.5000937660729403 0.2191503792858716 0.2135043433303477 5.4092173413022895 0.06361420665129658 0.19665861497698334 6.693134849305153e-06 5.174370425001109 -0.5927887273905934 SPSSES(ph)SPQHPTPPARPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSSESSPQHPTPPARPR 18 1 O14733;O14733-4;O14733-3;O14733-2 O14733 MAP2K7 Dual specificity mitogen-activated protein kinase kinase 7 1 S(0.05)PS(0.222)S(0.222)ES(0.248)S(0.208)PQHPT(0.049)PPARPR 70.538 0.0046767 3541600.0 2031.9 3189.5 7076.6 7075.2 8668.2 10050.0 7897.1 8791.7 7400.1 5477.5 True False 2375.860538145692 3506.132481328836 7245.332982154947 6678.799482107886 6969.728435194348 9522.960307986135 7149.029517947164 8560.927190576149 7508.312462886233 6470.5273901338605 0.3671818995416602 0.5418619333371375 1.119743808395355 1.032187807796254 1.0771499778861395 1.4717440687302503 1.1048604057913225 1.3230648252304273 1.160386473958022 1.0 12.659667590716383 -5.142344323621658 1.4899814773886866 1.1996934271292519 0.24605400618616918 0.8104088393569582 0.1370974574243956 0.24202419149373863 0.7841068733339313 0.03964833561682926 0.27954512891000866 7.205359869189291e-06 5.142344323621658 -0.9536394209430827 down SPSSESS(ph)PQHPTPPARPR ddPTM_PC-9_AZD4547_30min_R2 1 SPSSESSPQHPTPPARPR 18 1 O14733;O14733-4;O14733-3;O14733-2 O14733 MAP2K7 Dual specificity mitogen-activated protein kinase kinase 7 1 S(0.002)PS(0.01)S(0.01)ES(0.045)S(0.789)PQHPT(0.143)PPARPR 94.18799999999999 0.00045928 6110200.0 2289.6 1436.2 6945.5 13188.0 11619.0 9109.7 6501.2 11000.0 6868.8 8108.4 True False 3017.6451733615017 1900.4235635782613 6853.39813189092 10147.710352568889 10005.902408538917 8540.069018911501 7079.794205506787 9300.202754853466 7231.8707450668735 7824.527384004883 0.38566484916779203 0.2428803006636746 0.875886529057439 1.2969103250009861 1.2787868094107846 1.091448543763723 0.9048206822024164 1.1885961027965983 0.9242565576357321 1.0 12.933787897877412 -5.388491639154079 3.7469804079534796 1.1043826764617262 0.3142899539893293 0.843776250281602 0.13256643163884957 0.08294577045419389 2.0400352367037575 0.037040377335037754 0.08442490113773071 4.087976220269795e-06 5.388491639154079 -0.7900927224723968 down SPSSESSPQHPT(ph)PPARPR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSSESSPQHPTPPARPR 18 1 O14733;O14733-4;O14733-3;O14733-2 O14733 MAP2K7 Dual specificity mitogen-activated protein kinase kinase 7 1 S(0.013)PS(0.069)S(0.069)ES(0.083)S(0.382)PQHPT(0.384)PPARPR 86.777 0.001232 4228100.0 8205.0 4985.0 8939.6 5539.5 8058.7 10066.0 5549.3 6482.0 10273.0 6998.8 True False 8087.9951953872815 4973.457538777485 8204.620595853921 5946.893309230286 7584.70311001379 9635.500644992077 5836.615601066568 6783.177383704403 9115.946560514185 8208.5332546852 0.9853155179423657 0.605888699535788 0.9995233425132259 0.7244769710637361 0.924002239460339 1.1738395089637241 0.7110424505785113 0.8263568134822084 1.110545121482094 1.0 13.00290874110661 -6.498514121473497 23.81691582385036 0.9500328984209211 0.824969016170855 0.13143209528914146 0.16279973642567558 935.0579737774889 914038.9956067393 0.049815467958627006 0.05614948703188517 3.173115485470749e-07 6.498514121473497 -0.12506388225006604 SPSSKPS(ph)LAVAVDSAPEVAVK ddPTM_PC-9_AZD4547_30min_R2 1 SPSSKPSLAVAVDSAPEVAVK 21 1 Q5SRN1;O60508 Q5SRN1 CDC40 Pre-mRNA-processing factor 17 1 S(0.21)PS(0.21)S(0.21)KPS(0.37)LAVAVDSAPEVAVK 83.213 0.00026091 21944000.0 41257.0 46819.0 52283.0 43342.0 45841.0 56221.0 62275.0 63688.0 57152.0 47969.0 True False 54375.867801089924 61952.32615455409 51589.693258894644 33350.17152722479 39476.76842325781 52705.49198241692 67817.35435733949 53846.483004646165 60172.93804187952 46289.61991062728 1.174688146199407 1.3383632502095988 1.1144980960850481 0.7204676035710584 0.8528211832258886 1.1386028246543598 1.4650661312034194 1.1632517853594204 1.2999229234989866 1.0 15.49840109609361 -7.002400126322594 24.99197233989428 1.2536888129952464 1.038363380846439 0.178263245060294 0.19215080636621956 165.34387764152208 1721708.2594380898 0.07490667504780772 0.06495280240475147 9.944887478892782e-08 7.002400126322594 -0.2153254321488074 SPSSSVGS(ph)PPVLYMQPSPL ddPTM_PC-9_AZD4547_30min_R2 1 SPSSSVGSPPVLYMQPSPL 19 0 F5H148;Q9NYV6-3;Q9NYV6;Q9NYV6-4 F5H148 RRN3 RNA polymerase I-specific transcription initiation factor RRN3 1 SPSSS(0.006)VGS(0.994)PPVLYMQPSPL 187.56 4.6973e-11 4355400.0 8952.1 9326.5 14514.0 17115.0 15621.0 11196.0 11273.0 16104.0 9825.5 11169.0 True False 11798.681584752572 12341.10873535207 14321.534876720863 13169.401174114084 13452.293788087305 10495.912350102988 12276.275161305302 13615.496833105477 10344.855870844194 10777.976709579016 1.0947028280610773 1.1450301914629124 1.3287776790232326 1.2218806487501193 1.2481279325953143 0.9738295630918055 1.1390148162404787 1.2632702036741823 0.9598142721583466 1.0 13.395798753834434 -6.7356585050360875 24.99443223697798 1.0881293952526536 1.2117359314709732 0.31200974890663513 0.10189806600613947 324.9971875198149 315082.5133021494 0.034313216849197484 0.034301223912632475 1.8379830203222833e-07 6.7356585050360875 0.12360653621831963 SPSVAAMAS(ph)PQLCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSVAAMASPQLCR 14 0 P25325-2 P25325-2 MPST 3-mercaptopyruvate sulfurtransferase 1 S(0.008)PS(0.002)VAAMAS(0.99)PQLCR 77.192 0.013576 28885000.0 23740.0 33872.0 29299.0 19553.0 27046.0 20792.0 21184.0 20324.0 18393.0 14258.0 True False 27758.713113627015 37234.58830775052 29997.59927707625 18457.508801681306 21746.530451335515 19701.630917775885 19177.298161121522 19790.51653505802 18661.96282886266 16842.862533734096 1.6480994877224622 2.2107042810077213 1.7810273768484959 1.09586531177306 1.2911421919985395 1.1697317411643087 1.138600883472857 1.1750090874054306 1.1080042238357724 1.0 14.039849732458812 -5.68803161728744 4.49446781916121 1.153625378619759 1.9417307534864932 0.8441239282217958 0.146185922901435 0.0683463070821094 2.59996879627408 0.037651437682846615 0.06620840940579438 2.0510128565884977e-06 5.68803161728744 0.7881053748667342 SPSVAAMAS(ph)PQLCR ddPTM_PC-9_Lapatinib_30min_R1 1 SPSVAAMASPQLCR 14 0 P25325-2 P25325-2 MPST 3-mercaptopyruvate sulfurtransferase 1 S(0.018)PS(0.078)VAAMAS(0.904)PQLCR 63.693999999999996 0.038333 19170000.0 18442.0 16219.0 33521.0 22586.0 22725.0 29246.0 28444.0 21137.0 28020.0 24805.0 True False 18179.013698151397 16181.445901992398 30765.032774801923 24247.049784687293 21388.360179069 27995.21675575581 29916.6911424391 22119.1021844122 24864.09253631925 29092.511199415087 0.6248691827784496 0.5562065712057792 1.0574897630501028 0.8334464363865154 0.7351843927278103 0.9622825806910289 1.0283296253587275 0.7603022658579198 0.8546561129043804 1.0 14.828360211518033 -5.24549283940752 24.95221883165876 0.8933792447645884 0.5905378203923026 0.5837353684859471 0.10556672921347776 575.5121062304222 900524.3845174008 0.027310944088199313 0.07175479346782042 5.6820776002034195e-06 5.24549283940752 -0.3028414243722858 SPSVPKS(ph)PTPK ddPTM_PC-9_AZD4547_30min_R2 1 SPSVPKSPTPK 11 1 Q9NVD7-2;Q9NVD7 Q9NVD7-2 PARVA Alpha-parvin 1 S(0.001)PS(0.002)VPKS(0.968)PT(0.03)PK 69.045 0.016843 91433000.0 177320.0 171840.0 167980.0 126740.0 147300.0 164110.0 167410.0 177370.0 165830.0 134830.0 True False 233704.07151487615 227383.91948564837 165752.47544381797 97522.05111348056 126849.93758307824 153848.17575700275 182309.16568385685 149961.54205712397 174595.435251345 130109.64273905814 1.796208694413082 1.7476331092667667 1.2739445897660593 0.7495374597950919 0.9749464752392148 1.1824502205847534 1.4011964205411558 1.152578232482583 1.3419100350733075 1.0 16.989368362059764 -5.312331231526006 3.8268551849260244 1.1235856361178078 1.785312585557403 0.6820309428159594 0.17644228744596607 0.13228936372191222 4.00798652101249 0.05157442830332333 0.12507550896789743 4.871567993571227e-06 5.312331231526006 0.6617269494395952 SPSVPKS(ph)PTPK ddPTM_PC-9_Lapatinib_30min_R1 1 SPSVPKSPTPK 11 1 Q9NVD7-2;Q9NVD7 Q9NVD7-2 PARVA Alpha-parvin 1 SPS(0.001)VPKS(0.947)PT(0.051)PK 59.708999999999996 0.03146 73824000.0 100880.0 136880.0 114560.0 123680.0 130260.0 139700.0 141350.0 154610.0 148330.0 123980.0 True False 99441.43270087366 136563.0627698821 105141.31901438825 132775.8397843852 122598.36290101349 133725.35665660558 148668.4113691381 161793.74503155483 131623.51341585422 145409.77780703417 0.6838703297713394 0.9391601089653537 0.7230691126831641 0.9131149348194808 0.8431232393718905 0.9196448730845708 1.0224100030358914 1.1126744533387773 0.9051902519961553 1.0 17.149764758270862 -6.909892532483728 1.6759680943306858 1.0206972561620753 0.8183596816174276 0.5213504327517349 0.08563156743598595 0.28619638704723377 1.6465062937540043 0.03710080393933718 0.030091362304261328 1.2305732423043724e-07 6.909892532483728 -0.20233757454464774 SPSYT(ph)NDSTATFIIDGMHCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPSYTNDSTATFIIDGMHCK 20 0 Q04656-5;Q04656;Q04656-2;Q04656-3 Q04656-5 ATP7A Copper-transporting ATPase 1 1 S(0.133)PS(0.132)Y(0.107)T(0.6)NDS(0.016)T(0.012)ATFIIDGMHCK 73.76 0.002698 10035000.0 9969.1 8420.1 10548.0 9787.9 13488.0 10789.0 13715.0 7591.3 9281.1 11118.0 True False 11656.671731299877 9255.991881497708 10799.504323512765 9239.515695799955 10845.123224418154 10223.205847050987 12415.815911998763 7392.03641864721 9416.818529383854 13133.605389960427 0.8875454519297843 0.7047563564360751 0.8222802500041693 0.7035018505172094 0.8257536984252907 0.7784005643161623 0.9453471109684508 0.5628337535021283 0.7170017866215355 1.0 13.68097539358722 -4.734485729784707 24.008308092603713 0.7755544896066467 0.8875463864648535 0.058422528407122476 0.11949860858880726 4932.057179911568 4392725.94373621 0.028471899762049276 2.2495211654917884 1.8429530444363573e-05 4.734485729784707 0.11199189685820676 SPT(ph)FSEELPVLGDGQQLR ddPTM_PC-9_AZD4547_30min_R2 2 SPTFSEELPVLGDGQQLR 18 0 Q8N0Z3 Q8N0Z3 SPICE1 Spindle and centriole-associated protein 1 1 S(0.426)PT(0.573)FS(0.001)EELPVLGDGQQLR;S(0.439)PT(0.547)FS(0.014)EELPVLGDGQQLR 139.02 0.00027094 4468300.0 6592.700000000001 7344.700000000001 13198.9 16448.2 14093.0 14655.2 10279.5 16857.8 12881.800000000001 14239.0 True False 8689.041463321268 9718.73064156333 13023.873961991943 12656.32161215678 12136.43021288742 13738.808027262356 11194.355585969824 14252.814363706262 13562.705649284077 13740.49694401429 0.6323673371294213 0.7073056150124946 0.9478459196241424 0.9210963521716146 0.8832599186432161 0.9998770847401796 0.8146980150413242 1.0372852176874978 0.9870607813200188 1.0 13.74614656170403 -5.183365810623344 3.283653148648859 0.9452592678441913 0.6440584330499511 0.7671452854107381 0.061979559038374536 0.1141261505688953 2.3518470722605502 0.016154074384611587 0.05216369397300181 6.555928212234878e-06 5.183365810623344 -0.3012008347942402 SPT(ph)FSEELPVLGDGQQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPTFSEELPVLGDGQQLR 18 0 Q8N0Z3 Q8N0Z3 SPICE1 Spindle and centriole-associated protein 1 1 S(0.136)PT(0.778)FS(0.086)EELPVLGDGQQLR 107.14 0.00073987 9955300.0 472.01 0.0 864.2 717.69 809.15 0.0 826.2 0.0 782.9 0.0 True False 551.9119703775519 0.0 884.805805496751 677.4801560823737 650.6028660318759 0.0 747.9363548299945 0.0 794.3484313987153 0.0 0.0 SPT(ph)GPSNSFLANMGGTVAHK ddPTM_PC-9_AZD4547_30min_R2 1 SPTGPSNSFLANMGGTVAHK 20 0 H0Y6J6;Q5W012;Q96I25 H0Y6J6 RBM17 Splicing factor 45 1 S(0.432)PT(0.566)GPS(0.001)NS(0.001)FLANMGGTVAHK 101.05 0.00070296 14015000.0 11729.0 10878.0 18115.0 17445.0 18469.0 23291.0 20331.0 30300.0 13669.0 17211.0 True False 15458.578021644415 14394.10076911595 17874.783263869267 13423.324772563265 15904.89814814574 21834.610088089375 22140.419613634178 25617.831224732734 14391.515434183424 16608.44812862069 0.9307659512754386 0.8666734337635771 1.0762464455102432 0.8082226989908451 0.9576390295452981 1.314668891337454 1.3330817811617486 1.5424578519522558 0.8665177699163288 1.0 14.01962965563489 -6.7187948821636105 6.976774627266286 1.2527723205057497 0.9243205504813689 0.3560687806319468 0.18656203079262215 0.1949224234002988 24.309410962425595 0.06012759610925446 0.05941951404521498 1.910755497737896e-07 6.7187948821636105 -0.32845177002438086 SPT(ph)GPSNSFLANMGGTVAHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPTGPSNSFLANMGGTVAHK 20 0 H0Y6J6;Q5W012;Q96I25 H0Y6J6 RBM17 Splicing factor 45 1 S(0.116)PT(0.846)GPS(0.037)NS(0.001)FLANMGGTVAHK;S(0.258)PT(0.656)GPS(0.085)NS(0.001)FLANMGGTVAHK 128.95 1.8717e-05 56550000.0 123419.0 178464.0 160627.0 142056.0 179743.0 133163.0 168725.0 99246.0 114437.0 131129.0 True False 144311.3990636364 196180.72649251277 164456.95686129 134097.06287176575 144523.6494459217 126179.69785993603 152742.14653678384 96640.8976598293 116110.42463146616 154901.64968340693 0.9316324219824952 1.2664857146032555 1.0616862841513472 0.8656916381835683 0.9330026487213267 0.8145794322902709 0.9860588757380134 0.6238855290266252 0.749575132794108 1.0 17.240992983169825 -5.737547649426222 3.6238646854944028 0.8421203910653049 1.1136171116032016 0.4053163072778798 0.12947191661973614 0.20514774057824034 5.679497545437588 0.03669721501903478 0.06357326619009997 1.830005312862062e-06 5.737547649426222 0.27149672053789675 SPT(ph)GPSNSFLANMGGTVAHK ddPTM_PC-9_Lapatinib_30min_R1 2 SPTGPSNSFLANMGGTVAHK 20 0 H0Y6J6;Q5W012;Q96I25 H0Y6J6 RBM17 Splicing factor 45 1 S(0.378)PT(0.457)GPS(0.137)NS(0.027)FLANMGGTVAHK;S(0.462)PT(0.518)GPS(0.018)NS(0.003)FLANMGGTVAHK 166.85 8.3647e-08 149179000.0 95450.0 102041.1 105432.4 89409.5 101647.0 116074.5 113365.0 111334.0 110389.0 102172.4 True False 94088.86549661391 101804.83010233632 96764.15505283354 95984.97289134862 95668.32330569108 111110.2642178753 119234.4850007949 116506.98408474943 97955.82837229635 119832.76320383462 0.7851681208132493 0.8495575615590795 0.8074933137295552 0.8009910672599522 0.798348638117941 0.9272110668839171 0.9950073904077297 0.9722464956146587 0.8174377837359407 1.0 16.87066288047238 -6.806827604156946 5.488284029657252 0.9455401955869082 0.8099961985079377 0.6422372277922435 0.05009655412396108 0.125474793092331 8.664671008065222 0.01760152517251885 0.015786878821880772 1.5601716995924212e-07 6.806827604156946 -0.13554399707897047 SPT(ph)PPPSSKPSSIPR ddPTM_PC-9_Lapatinib_30min_R1 1 SPTPPPSSKPSSIPR 15 1 R4GND2;F6S7C4;Q8NEM7-2;Q8NEM7;Q8NEM7-3;H7C5F9;B4E2D5 R4GND2 SUPT20H Transcription factor SPT20 homolog 1 S(0.145)PT(0.855)PPPSSKPSSIPR 106.3 0.012659 0.0 4497.3 3847.4 4656.4 3320.6 5112.6 6688.2 4766.6 5362.5 5851.8 3951.2 True False 4433.167677296187 3838.491581683551 4273.568766223792 3564.8080011968764 4811.886919758339 6402.161276955693 5013.391224847075 5611.66132676872 5192.708661814165 4634.159655356938 0.9566281714467022 0.8283036984378342 0.9221885053709113 0.7692458323217402 1.038351562660547 1.3815150433056407 1.0818339456759454 1.2109339651865083 1.1205286498516644 1.0 12.178092033229074 -6.519288346379284 24.813242307830073 1.172059423527479 0.8741992404576013 0.6324240722904411 0.10392425425632927 79.51928161451401 549562.8290300372 0.031846491015543835 0.03251931799623016 3.024904399933311e-07 6.519288346379284 -0.2978601830698777 SPT(ph)PPPTLHLVPEPAAPPPPPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPTPPPTLHLVPEPAAPPPPPPR 23 0 A0A087WWH3;Q9NZM4-2;Q9NZM4 A0A087WWH3 GLTSCR1 Glioma tumor suppressor candidate region gene 1 protein 1 S(0.417)PT(0.583)PPPT(0.001)LHLVPEPAAPPPPPPR 147.64 9.0995e-06 6153900.0 9988.9 13316.0 12980.0 11586.0 14847.0 8057.8 11648.0 8903.3 7766.5 6578.0 True False 11679.823480232053 14637.924477621815 13289.492426924122 10936.873982318806 11937.836930081277 7635.234783053797 10544.617115782834 8669.597808826118 7880.070369725531 7770.539328580655 1.5030904531005644 1.8837720084347784 1.7102406750641264 1.4074793936235703 1.5362945125537135 0.9825874962077347 1.3569993883177327 1.1157009111244898 1.014095680687441 1.0 12.9237990196742 -6.412255996306659 0.9524664567495427 1.0839283154673969 1.7313919984159032 0.7219296623268832 0.15831926764810586 0.28998014704671904 0.5675086279931544 0.07815557368035288 0.10447652306008309 3.8702944189689564e-07 6.412255996306659 0.6474636829485063 SPT(ph)SPLNMK ddPTM_PC-9_AZD4547_30min_R2 1 SPTSPLNMK 9 0 A0A0A0MRP6;B7ZLQ5;P28370-2;P28370 A0A0A0MRP6 SMARCA1 Probable global transcription activator SNF2L1 1 S(0.301)PT(0.418)S(0.281)PLNMK 80.916 0.043991 4997400.0 43482.0 41449.0 59987.0 66450.0 56605.0 57305.0 47416.0 62937.0 49112.0 52972.0 True False 57308.37151821488 54846.57867062758 59191.533185190456 51130.97914226589 48746.372823422455 53721.709291055 51635.93214303668 53211.53279838301 51707.96005586485 51117.466403421924 1.1211113451111598 1.0729518211598223 1.1579512317384344 1.0002643468034453 0.9536148063112779 1.0509462434440753 1.0101426337432884 1.0409657704557302 1.0115517003089065 1.0 15.641528711573773 -5.773677161274571 24.99999460164348 1.0107552333336667 1.1128995023573074 0.7143511529667177 0.031165181207213965 118.69252253784006 242471.25568097725 0.008822843157494518 0.013194105260884803 1.6839253648089692e-06 5.773677161274571 0.10214426902364071 SPT(ph)SPLNMK ddPTM_PC-9_Lapatinib_30min_R1 1 SPTSPLNMK 9 0 A0A0A0MRP6;B7ZLQ5;P28370-2;P28370 A0A0A0MRP6 SMARCA1 Probable global transcription activator SNF2L1 1 S(0.013)PT(0.789)S(0.198)PLNMK 100.82 0.0090399 22127000.0 264010.0 228550.0 285330.0 246280.0 243110.0 268390.0 188050.0 198630.0 262390.0 181030.0 True False 260245.16898649512 228020.80651706972 261871.26880565158 264392.25276599586 228810.74777265007 256911.585347648 197786.3088642833 207859.0749344653 232836.8751108068 212320.7942926876 1.225716820876918 1.0739447696429554 1.2333755140566112 1.2452489811314802 1.0776652778400535 1.210016127734956 0.9315446917160252 0.9789859520209228 1.0966277508826452 1.0 17.69588614739385 -7.254842829757646 24.878263467889987 1.0000384263535962 1.1740062319719835 0.6154334655425361 0.06806535281528417 334.25775783790874 1260625.3970822939 0.02628078999618147 0.019859348516961025 5.5610547423766506e-08 7.254842829757646 0.17396780561838732 SPTAALNES(ph)LVECPK ddPTM_PC-9_AZD4547_30min_R2 1 SPTAALNESLVECPK 15 0 Q53EZ4 Q53EZ4 CEP55 Centrosomal protein of 55 kDa 1 SPTAALNES(1)LVECPK 157.47 2.6394e-14 0.0 9174.4 6031.7 10375.0 13459.0 11147.0 11181.0 9756.3 10075.0 7214.6 6525.4 True False 12091.66836062533 7981.329068677756 10237.42072109543 10356.235489477147 9599.431461225866 10481.850302474228 10624.591799542528 8518.14025046807 7595.949027102182 6296.947732177183 1.920242770769293 1.2674917131507133 1.6257750828679374 1.6446437115171126 1.5244578595075684 1.6645922355226705 1.6872605985358962 1.3527411394794768 1.2062906268519824 1.0 12.620436976970952 -8.208272774549656 1.7583079153623458 1.0251976810496652 1.604791942004341 0.6375796910243421 0.1577891903218383 0.2186283084724464 1.2308613184059372 0.13903675294142911 0.042001238896303465 6.190521345876792e-09 8.208272774549656 0.5795942609546758 SPTAPSVFS(ph)PTGNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPTAPSVFSPTGNR 14 0 H0Y3X6;A0A0C4DFX9;Q9H3P2;C9JEM7;H7C2C7;C9JHL4 H0Y3X6 NELFA Negative elongation factor A 1 SPTAPS(0.08)VFS(0.84)PT(0.08)GNR 66.67399999999999 0.036081 12496000.0 73675.0 58940.0 44423.0 69615.0 72695.0 63242.0 82847.0 73379.0 65487.0 59159.0 True False 86146.72235242075 64791.17367911008 45482.21279516568 65714.69724487503 58450.9365954239 59925.478188821784 74999.13239966184 71452.87900147728 66444.62348576779 69884.0583976138 1.2327092090484866 0.9271237985417627 0.6508238622374953 0.9403388805925282 0.8363987143228034 0.8574985420547349 1.0731937171270909 1.0224489052272479 0.950783698160789 1.0 16.092675772293212 -7.254794341755046 24.827507799077093 1.0134773228226341 0.8949711024079827 0.11690352281873295 0.13760833016729304 1015.4285640057037 3793901.1291237506 0.05527998625848105 0.041867211690122794 5.561675656298424e-08 7.254794341755046 -0.11850622041465142 SPTGPS(ph)NSFLANMGGTVAHK ddPTM_PC-9_Lapatinib_30min_R1 1 SPTGPSNSFLANMGGTVAHK 20 0 H0Y6J6;Q5W012;Q96I25 H0Y6J6 RBM17 Splicing factor 45 1 S(0.074)PT(0.239)GPS(0.55)NS(0.137)FLANMGGTVAHK 75.10600000000001 0.0013551 2815600.0 21885.0 23029.0 19269.0 16434.0 16792.0 20458.0 16909.0 17438.0 23696.0 16393.0 True False 21572.91588678252 22975.677765397544 17684.777200490993 17642.611182216893 15804.327574342216 19583.05902992727 17784.46528362758 18248.233140548793 21027.106950057838 19226.50820770053 1.122040240158752 1.19500002377943 0.9198122201621587 0.9176191012755368 0.8220071686242187 1.0185447517757766 0.9249971493266058 0.9491184225141868 1.093651885350463 1.0 14.230809153207305 -5.262663366384512 24.99541997252776 0.9489120927091234 1.1585201437337498 0.5689606500990358 0.07040791346773058 69.65470766653522 1422479.5507294242 0.018438911998461212 0.04216223369244787 5.461810570364349e-06 5.262663366384512 0.20960805102462643 SPTGPSNS(ph)FLANMGGTVAHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPTGPSNSFLANMGGTVAHK 20 0 H0Y6J6;Q5W012;Q96I25 H0Y6J6 RBM17 Splicing factor 45 1 S(0.157)PT(0.157)GPS(0.157)NS(0.528)FLANMGGTVAHK 69.612 0.003164 194660000.0 37690.0 48086.0 36426.0 42931.0 44406.0 47608.0 46181.0 37082.0 37356.0 39994.0 True False 44070.17258856787 52859.66029069711 37294.53398637427 40525.71525417994 35704.96307113821 45111.35267090586 41806.40135851367 36108.63679162673 37902.26082939126 47244.59560767021 0.9328087587951124 1.118850941802014 0.789392596268079 0.8577852076608852 0.7557470354416892 0.9548468367794004 0.8848927760051851 0.7642913718953381 0.8022560113359885 1.0 15.527861685900172 -5.268819941802157 24.99018044486532 0.8444713814423509 1.0258298535452193 0.39378888462263784 0.08637450742364144 464.00109820358955 1571086.2908509986 0.021698314943246564 0.04665618816797025 5.384929950719835e-06 5.268819941802157 0.18135847210286837 SPTLSQVHSPLVT(ph)SPSANLK ddPTM_PC-9_AZD4547_30min_R2 1 SPTLSQVHSPLVTSPSANLK 20 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 SPTLSQVHSPLVT(0.903)S(0.094)PS(0.004)ANLK 108.96 0.00019238 16855000.0 17975.0 13191.0 37476.0 48869.0 40586.0 35332.0 33036.0 35478.0 31213.0 35955.0 True False 23690.67609677367 17454.73278593569 36979.04375361658 37603.00706852356 34951.33446535507 33122.68445461225 35976.140000787884 29995.69030333558 32862.85545739758 34696.22639385028 0.6828026721941356 0.5030729448153891 1.0657943989024383 1.0837780063364035 1.0073526172157443 0.954648038049552 1.0368891300284016 0.8645231317908438 0.9471593563045906 1.0 15.082491141519418 -5.262992899287524 24.999999620066507 0.9938437544715495 0.5929377893642385 0.8328030965663813 0.07206201748824104 48.89520601478614 786861.0073610651 0.019502618412509314 0.044420137030362926 5.4576678430235244e-06 5.262992899287524 -0.400905965107311 SPTLSQVHSPLVT(ph)SPSANLK ddPTM_PC-9_Lapatinib_30min_R1 1 SPTLSQVHSPLVTSPSANLK 20 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 SPTLSQVHSPLVT(0.865)S(0.101)PS(0.033)ANLK 121.92 1.9408e-05 7950300.0 26598.0 14891.0 33078.0 21725.0 27133.0 19643.0 15346.0 18388.0 27159.0 16445.0 True False 26218.707642524165 14856.520804400312 30358.45452477248 23322.7289724755 25537.090285530456 18802.914680069465 16140.540791445306 19242.37360869431 24100.06742305118 19287.496338414887 1.359362935577304 0.7702669410135204 1.5739966448785567 1.2092149526957339 1.3240230788621465 0.9748758651800606 0.8368396036606476 0.9976605190778076 1.2495176667928174 1.0 14.235378262460758 -6.770724504201553 24.849601284522198 1.0006987713347724 1.2368929025958515 0.23651656217827077 0.21075403458343236 282.6910617402764 756555.5891617441 0.07331332594137513 0.06552481827601667 1.6954129488740508e-07 6.770724504201553 0.23619413126107913 SPTS(ph)PLNMK ddPTM_PC-9_AZD4547_30min_R2 4 SPTSPLNMK 9 0 A0A0A0MRP6;B7ZLQ5;P28370-2;P28370 A0A0A0MRP6 SMARCA1 Probable global transcription activator SNF2L1 1 S(0.008)PT(0.04)S(0.952)PLNMK;SPT(0.007)S(0.993)PLNMK;S(0.015)PT(0.028)S(0.957)PLNMK;S(0.006)PT(0.009)S(0.985)PLNMK 92.611 0.0068949 189189500.0 688951.0 656794.0 911127.0 1161502.0 1066619.0 915042.0 911583.0 1009334.0 873778.0 921377.0 True False 908023.0869289751 869089.8161933025 899044.860660194 893735.6589270143 918537.3630341161 857824.2790874348 992712.1210297301 853364.6224879337 919964.1212268587 889119.8716753329 1.0212605924755946 0.9774720415996455 1.0111627119143787 1.0051914116405745 1.033086080174266 0.964801604839931 1.1165110044826716 0.9597857945520586 1.0346907661544076 1.0 19.762018411616943 -5.878667280620734 1.959317009493765 1.0185352609319769 0.9995028090428086 0.024321743504847615 0.04225909312878708 1.4059125626558069 10.996511329007005 0.012711313424551937 0.02260411695420687 1.322308286026501e-06 5.878667280620734 -0.019032451889168245 SPTS(ph)PLNMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPTSPLNMK 9 0 A0A0A0MRP6;B7ZLQ5;P28370-2;P28370 A0A0A0MRP6 SMARCA1 Probable global transcription activator SNF2L1 1 S(0.046)PT(0.025)S(0.93)PLNMK 73.499 0.025913 89680000.0 574090.0 597360.0 654360.0 766010.0 764290.0 746890.0 817180.0 737900.0 646360.0 577990.0 True False 671272.0982056512 656661.9529852946 669962.4240741187 723092.9431379262 614532.8610016706 707721.7735753001 739770.7945291387 718530.9068696767 655811.7922070181 682775.0116336767 0.983152702966527 0.9617545191264377 0.9812345394291726 1.0590500982274977 0.9000517747878279 1.0365373095332433 1.0834766678983874 1.0523684883406128 0.9605093640405151 1.0 19.381050733663827 SPTS(ph)PLNMK ddPTM_PC-9_Lapatinib_30min_R1 3 SPTSPLNMK 9 0 A0A0A0MRP6;B7ZLQ5;P28370-2;P28370 A0A0A0MRP6 SMARCA1 Probable global transcription activator SNF2L1 1 S(0.004)PT(0.157)S(0.839)PLNMK;SPT(0.028)S(0.972)PLNMK;S(0.012)PT(0.123)S(0.864)PLNMK 99.28299999999999 0.0041909 172756000.0 684720.0 613480.0 631210.0 584000.0 568800.0 582550.0 558520.0 528030.0 609260.0 469899.0 True False 674955.7672377302 612059.524752099 579314.3503410605 626949.3081668909 535344.3023038262 557635.694490376 587437.4327406512 552564.2014682869 540638.7230077754 551120.4160489399 1.2246974482937565 1.1105731287184752 1.0511574847730136 1.1375904247234734 0.9713744704683327 1.0118218782170059 1.065896699948213 1.0026197276988897 0.980981120031246 1.0 19.072008046693412 -1.5228787452807453 0.43450553163876077 1.0036955283988098 5.343379942473779 0.7242886050011896 0.040312108490872606 44.861146790712596 0.5587022445173074 0.026534814053039885 170.95916546584297 0.029999999999971834 1.5228787452807453 4.339684414074969 SPTTTQS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 SPTTTQSPK 9 0 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 SPTTT(0.003)QS(0.996)PK;SPT(0.001)T(0.004)T(0.021)QS(0.973)PK 87.29799999999999 0.010998 37623000.0 59113.0 41455.0 31700.0 39238.0 38944.0 41993.0 47804.0 31191.0 50666.0 67704.0 True False 77909.70437321736 54854.51805329121 31279.63728758797 30192.285321056865 33537.29782237196 39367.17107162151 52058.46339138109 26371.14764787587 53344.10132331097 65333.70356749374 1.1924887174463 0.8396052122871485 0.47876724538161497 0.4621241973503978 0.5133230781525475 0.6025553263018802 0.7968086997793029 0.4036377276642958 0.8164867198780982 1.0 15.995539803568493 -4.896321176372777 3.0378306413699927 0.6080610627524565 1.2191832562464398 0.4688313119118298 0.18023356006516203 0.23700310292187735 3.7114107140765786 0.04400448250806602 0.30784309756511724 1.2696348173696874e-05 4.896321176372777 0.6111221934939832 SPTTTQS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 SPTTTQSPK 9 0 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 SPT(0.002)T(0.246)T(0.246)QS(0.506)PK 127.52 0.0013595999999999999 26214000.0 113890.0 188190.0 105540.0 135380.0 171800.0 101840.0 190390.0 199790.0 145730.0 140800.0 True False 112265.9077151321 187754.25761735876 96862.90859618157 145336.2968144413 161695.06177179582 97484.54060063511 200247.46261457563 209072.97276925368 129316.35279506784 165137.09239579338 0.6798345912864813 1.1369599336735174 0.5865605794004461 0.8800948030870351 0.9791565264105059 0.590324918444055 1.212613469871634 1.2660570059460456 0.7830848352660106 1.0 17.33330468315002 -7.276845556077835 24.93660710291874 1.0876102409471737 0.8246166200540076 0.27628315053975716 0.20122730146513115 1041.0381509614883 1685028.9259972256 0.08096903390533708 0.05481242198054671 5.286332110389005e-08 7.276845556077835 -0.26299362089316614 SPTTVLFTSS(ph)PIK ddPTM_PC-9_AZD4547_30min_R2 1 SPTTVLFTSSPIK 13 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 SPTTVLFT(0.001)S(0.23)S(0.769)PIK 117.27 0.00026127 8489900.0 28276.0 37358.0 43227.0 55649.0 52118.0 51229.0 40793.0 47055.0 43355.0 43929.0 True False 37267.179822663275 49433.2429244929 42653.78173597994 42819.98281847937 44882.315322164686 48025.64253156712 44423.49797348773 39783.73096633002 45646.656789013265 42391.05908094694 0.8791283027748971 1.16612427234004 1.0061975959253888 1.0101182595299965 1.0587684359680805 1.1329191478764609 1.047944989736156 0.938493442458275 1.0767991595078967 1.0 15.371472390097761 -7.584163112502187 24.999892617318356 1.0032314343710949 1.0492444178150304 0.041909298927131244 0.07917708356980742 208.20885519314496 84931.81944774115 0.03552074382584196 0.020507887506215763 2.605174913554227e-08 7.584163112502187 0.04601298344393556 SPTTVLFTSS(ph)PIK ddPTM_PC-9_Lapatinib_30min_R1 2 SPTTVLFTSSPIK 13 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 SPTTVLFTS(0.168)S(0.831)PIK;SPTTVLFT(0.001)S(0.189)S(0.81)PIK 139.48 6.8597e-05 12199100.0 82850.0 83906.0 119201.0 86571.0 106274.0 92723.0 77370.0 81243.0 100491.0 68893.0 True False 81668.54380717092 83711.72081216944 109400.75390916657 92937.72013239007 100023.1722627231 88757.45343787015 81375.84002568258 85017.84637215325 89172.64536285723 80801.06325584766 1.0107360041609412 1.0360225155343006 1.3539519098005077 1.1502041729093715 1.2378942582229489 1.0984688797575528 1.0071134802770472 1.0521872231180127 1.1036073260632955 1.0 16.30208665698006 -6.996469764178105 24.228931571371753 1.0461781090889433 1.1621484332919476 0.25487766400532375 0.09407168924883386 107.55676624520427 738179.4680575202 0.03500314917149336 0.030709632402274183 1.0081617957025595e-07 6.996469764178105 0.11597032420300435 SPVDIVTGGIS(ph)PVRDLDR ddPTM_PC-9_AZD4547_30min_R2 1 SPVDIVTGGISPVRDLDR 18 1 E9PEM5;A0A494C1L5;P50851-2;P50851;A0A494C0R9;A0A494BZW2;H0YAC6;H0Y9N9 E9PEM5 LRBA Lipopolysaccharide-responsive and beige-like anchor protein 1 SPVDIVT(0.042)GGIS(0.958)PVRDLDR 55.126999999999995 0.019133 2537400.0 9201.8 8648.6 11781.0 16236.0 13562.0 10158.0 10110.0 11279.0 9460.5 12567.0 True False 12127.780990669928 11444.090817409104 11624.776242431346 12493.041043699464 11679.150397160241 9522.818654193115 11009.770414334835 9536.089715635659 9960.562716006463 12127.033155097102 1.0000616668201745 0.9436843019266463 0.958583694276893 1.0301811567529628 0.963067408804056 0.7852554315966876 0.9078700679322649 0.7863497686264306 0.8213519818588068 1.0 13.565939021849445 -6.654170351681957 6.9684943026523785 0.8501675421344457 0.9805206315377023 0.46944014678003987 0.0629756542927845 0.17853179438149808 10.430986038440412 0.019780216767850186 0.019736812140070007 2.2173265045557015e-07 6.654170351681957 0.13035308940325663 SPVDIVTGGIS(ph)PVRDLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPVDIVTGGISPVRDLDR 18 1 E9PEM5;A0A494C1L5;P50851-2;P50851;A0A494C0R9;A0A494BZW2;H0YAC6;H0Y9N9 E9PEM5 LRBA Lipopolysaccharide-responsive and beige-like anchor protein 1 SPVDIVT(0.006)GGIS(0.994)PVRDLDR 51.431000000000004 0.029283999999999998 2510100.0 6756.5 6589.8 8165.9 7648.2 7220.6 8845.4 10155.0 8494.2 8865.5 4337.4 True False 7900.242003042159 7243.99179352901 8360.606025348205 7219.696149798951 5805.775263510804 8381.531652563242 9193.044884166788 8271.236250348842 8995.1411656218 5123.736285160493 1.5418908318765465 1.4138104286337412 1.6317401130816243 1.4090686460013244 1.133113599215801 1.635824169334801 1.7942072683935626 1.6142978073060132 1.7555823846113583 1.0 12.322980507827596 SPVDIVTGGIS(ph)PVRDLDR ddPTM_PC-9_Lapatinib_30min_R1 1 SPVDIVTGGISPVRDLDR 18 1 E9PEM5;A0A494C1L5;P50851-2;P50851;A0A494C0R9;A0A494BZW2;H0YAC6;H0Y9N9 E9PEM5 LRBA Lipopolysaccharide-responsive and beige-like anchor protein 1 SPVDIVT(0.065)GGIS(0.935)PVRDLDR 72.316 0.003848 2348900.0 10386.0 7016.4 9595.4 7702.6 8207.2 8788.3 5944.5 8041.6 10702.0 5735.0 True False 10237.89373544086 7000.153956886329 8806.503251315125 8269.07489912035 7724.468631976028 8412.444895527895 6252.277123338116 8415.24209330412 9496.62806294392 6726.287108592849 1.5220720689073657 1.0407159022313535 1.3092666294403037 1.2293669249646788 1.1484000767835199 1.250681804049217 0.9295287314380049 1.2510976646467598 1.4118677822735153 1.0 12.71559464564118 -4.746033881727433 24.994536994592355 1.182222457440696 1.5220729937587856 0.3524198600075523 0.14098138846049704 1011.5135709857335 1641032.2020626361 0.034222732989422126 0.8213046332064887 1.7945936151442754e-05 4.746033881727433 0.3398505363180895 SPVGKS(ph)PPSTGSTYGSSQK ddPTM_PC-9_Lapatinib_30min_R1 1 SPVGKSPPSTGSTYGSSQK 19 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.069)PVGKS(0.928)PPS(0.002)T(0.001)GSTYGSSQK 65.085 0.029535000000000002 0.0 9317.0 15467.0 19916.0 17216.0 19199.0 15767.0 13997.0 17541.0 15415.0 13668.0 True False 9184.137871471461 15431.187111789657 18278.58335798322 18482.122070892416 18069.75256668629 15092.682164672158 14721.69617215301 18356.018896568796 13678.80037285372 16030.495588534784 0.5729166525606404 0.9626144760506493 1.1402381951969283 1.1529351646564854 1.127211100049209 0.9414981640035283 0.9183556485104649 1.1450687095224463 0.8532986580051195 1.0 13.96853140716726 -4.776852393993834 3.7365543337632134 1.0407784227649588 0.5215283865071494 0.6482792119406096 0.10138324304068372 0.1628249919492709 3.9788375339347075 0.026194221406691323 0.23667676829470666 1.671658673413213e-05 4.776852393993834 -0.5192500362578094 SPVGKSPPSTGST(ph)YGSSQKEESAASGGAAYTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPVGKSPPSTGSTYGSSQKEESAASGGAAYTK 32 2 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.138)PVGKS(0.132)PPS(0.075)T(0.146)GS(0.146)T(0.2)Y(0.083)GS(0.036)S(0.036)QKEES(0.005)AAS(0.003)GGAAYTK 40.872 0.026677 15469000.0 21590.0 18967.0 19927.0 37549.0 31384.0 25922.0 27082.0 22200.0 27732.0 30846.0 True False 25244.760578062647 20849.91841146389 20402.13525356833 35445.25126550048 25234.53049192908 24562.604686927032 24516.596903299327 21617.273522844316 28137.528036210468 36438.13562319837 0.6928115323768254 0.5722004722489087 0.5599116119590732 0.9727515049626808 0.6925307801934711 0.6740905995006296 0.672827972232773 0.593259593366288 0.7721999919857779 1.0 15.153161524310281 -8.567980656886332 8.839388744770558 0.9999996652000417 0.6812396650786272 0.441557402016453 0.10941365814900657 1.54675628841283 303.2567866835912 0.10951424726139986 0.028295096724203373 2.7040787988390827e-09 8.567980656886332 -0.3187600001214145 SPVGS(ph)GAPQAAAPAPAAHVAGNPGGDAAPAATGTAAAASLATAAGSEDAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPVGSGAPQAAAPAPAAHVAGNPGGDAAPAATGTAAAASLATAAGSEDAEK 51 0 P16989-2;P16989;P16989-3 P16989-2 YBX3 Y-box-binding protein 3 1 S(0.218)PVGS(0.781)GAPQAAAPAPAAHVAGNPGGDAAPAATGTAAAASLATAAGSEDAEK 61.20399999999999 1.9768e-07 9746200.0 23636.0 43181.0 28532.0 25234.0 30323.0 21129.0 32670.0 18809.0 20529.0 21698.0 True False 27637.107967720644 47467.72430671278 29212.31108821256 23820.220789731808 24381.425825476836 20020.9580445213 29575.261089682775 18315.283679782817 20829.197787947665 25631.675638726516 1.0782403911964362 1.8519165494976264 1.1396957225877231 0.9293274901521534 0.9512224705527759 0.7811021927209446 1.1538559361682135 0.7145566266495089 0.8126350411705875 1.0 14.645640175645227 -5.511979414211966 4.951617381923885 0.9073224605859154 1.4772479316729852 0.5313758089118754 0.20875456850141003 0.12120373930756337 8.436497523197598 0.0529928577460536 0.1043284345047549 3.0762426268116754e-06 5.511979414211966 0.5699254710870698 SPVGS(ph)GAPQAAAPAPAAHVAGNPGGDAAPAATGTAAAASLATAAGSEDAEK ddPTM_PC-9_Lapatinib_30min_R1 1 SPVGSGAPQAAAPAPAAHVAGNPGGDAAPAATGTAAAASLATAAGSEDAEK 51 0 P16989-2;P16989;P16989-3 P16989-2 YBX3 Y-box-binding protein 3 1 S(0.477)PVGS(0.523)GAPQAAAPAPAAHVAGNPGGDAAPAATGTAAAASLATAAGSEDAEK 85.31 5.1719e-21 12940000.0 90665.0 164380.0 123450.0 128290.0 178410.0 175010.0 187400.0 189260.0 149190.0 151730.0 True False 89372.10047407536 163999.38820947672 113300.41753078088 137724.8745628941 167916.27456755572 167525.23026823587 197102.6550447578 198053.71052759912 132386.65115965268 177956.3283324833 0.5022136684405946 0.9215709817471046 0.636675405659623 0.7739251301340457 0.9435813614553267 0.9413839442407546 1.1075900300466 1.1129343495869786 0.7439277512643953 1.0 17.441163712097968 -6.265377483138475 2.1836426694258497 0.9953162416119412 0.7064306528651373 0.4843969857062025 0.13630588651358208 0.2771782299848798 2.5956450983188457 0.04486379263636093 0.05756500912442576 5.427783504903464e-07 6.265377483138475 -0.2888855887468039 SPVLSNTTTEPAST(ph)MSPPPAKK ddPTM_PC-9_AZD4547_30min_R2 2 SPVLSNTTTEPASTMSPPPAKK 22 1 A0A075B784;Q9P275 A0A075B784 USP36 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 36 1 SPVLSNTTTEPAS(0.048)T(0.589)MS(0.362)PPPAKK;SPVLSNTTTEPAS(0.115)T(0.591)MS(0.293)PPPAKK 101.04 0.00047963 0.0 15700.4 13136.599999999999 17683.1 21131.0 24136.0 19807.4 19667.2 17594.3 18314.0 24492.0 True False 20692.800611392784 17382.749049785663 17448.610540067708 16259.574420695575 20785.133017686152 18568.84014678723 21417.54269958518 14875.505211792592 19282.04065122798 23634.5425347846 0.8755320980271885 0.7354806645486056 0.7382673269172599 0.6879580764791715 0.8794387700584949 0.7856653082858777 0.906196625894641 0.6293967903080534 0.8158415007546375 1.0 14.52860932001564 -6.265493145653299 24.996413085310277 0.8185437826446257 0.7561044648668475 0.10840833034921693 0.10041556630418448 959.8996286607671 5918949.187803679 0.030204792637374685 0.0355208739016692 5.426338154971237e-07 6.265493145653299 -0.062439317777778225 SPVLSNTTTEPAST(ph)MSPPPAKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPVLSNTTTEPASTMSPPPAKK 22 1 A0A075B784;Q9P275 A0A075B784 USP36 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 36 1 SPVLSNTTTEPAS(0.048)T(0.572)MS(0.38)PPPAKK 71.89399999999999 0.0075312 0.0 11227.0 11941.0 13091.0 12763.0 15189.0 13423.0 13999.0 14855.0 11336.0 11147.0 True False 13127.509356642398 13126.423564680248 13403.139087893966 12047.930488204287 12212.824485148813 12719.074250158988 12672.913376016815 14465.071990173527 11501.767554394979 13167.862860396554 0.9969354553444263 0.996852997623408 1.0178674573081274 0.9149495719946662 0.9274720290321296 0.9659178854613276 0.9624123147676196 1.0985132624427945 0.8734726110329949 1.0 13.684733595235107 SPVLSNTTTEPASTMS(ph)PPPAKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPVLSNTTTEPASTMSPPPAKK 22 1 A0A075B784;Q9P275 A0A075B784 USP36 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 36 1 SPVLSNTTTEPAS(0.07)T(0.207)MS(0.723)PPPAKK 80.191 0.0013965 0.0 9679.4 8143.7 8430.4 13544.0 15015.0 12036.0 13294.0 16529.0 13255.0 12146.0 True False 11317.931243135688 8952.152716161674 8631.412708470038 12785.173590240454 12072.91853607937 11404.810971832954 12034.696079774814 16095.131263923135 13448.829299003663 14347.973652316909 0.7888173980099322 0.6239314995338092 0.6015771228487193 0.8910786916712735 0.8414371833007819 0.7948725895514387 0.8387732213204513 1.1217703387212519 0.9373330077750699 1.0 13.808559380688871 -6.874244408850764 0.6072297171957061 1.0284221262652922 0.6719572297741133 0.5970086070524365 0.09524595407515077 0.5741105155464485 0.45622542361924345 0.08265746283564929 0.08331290420523188 1.3358435293972452e-07 6.874244408850764 -0.35646489649117885 SPVPSPGS(ph)SSPQLQSSCK ddPTM_PC-9_AZD4547_30min_R2 1 SPVPSPGSSSPQLQSSCK 18 0 H0Y6J8 H0Y6J8 MICALL1 1 SPVPSPGS(0.365)S(0.365)S(0.27)PQLQSSCK 88.101 0.0015754000000000002 5436100.0 7123.7 6875.6 11796.0 15426.0 12606.0 14948.0 9421.2 14438.0 12884.0 12580.0 True False 9388.888417835144 9098.00324031381 11639.577332630519 11869.774029324208 10855.874495399054 14013.299196975655 10259.668548717244 12206.93885223404 13565.021936792682 12139.578029053993 0.7734114312181571 0.7494497105697828 0.9588123495539294 0.9777748452965946 0.8942546824459123 1.1543481300121992 0.8451421066006158 1.0055488603490854 1.1174212072550738 1.0 13.567430654028417 -5.318748846485819 3.8446585571875493 0.9935125325402362 0.7581420307671202 0.5409688377196866 0.08614683831449217 0.16213166215224825 4.856666076232748 0.022490021395697266 0.053981513168340885 4.800109598465166e-06 5.318748846485819 -0.23537050177311603 SPVPSPGS(ph)SSPQLQVK ddPTM_PC-9_AZD4547_30min_R2 2 SPVPSPGSSSPQLQVK 16 0 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 SPVPS(0.005)PGS(0.922)S(0.036)S(0.036)PQLQVK;SPVPSPGS(0.711)S(0.065)S(0.224)PQLQVK 273.44 3.3762e-82 243190000.0 140296.0 159644.0 226525.0 240481.0 234346.0 249313.0 214132.0 258864.0 218883.0 215852.0 True False 184907.20966191744 211245.80099142712 223521.1304911942 185041.82084441307 201811.10300640858 233723.41869785867 233189.33317134957 218862.51690294445 230452.7085214993 208295.08718023574 0.8877175749321394 1.0141660269146826 1.0730984274141018 0.8883638272481106 0.9688711612856398 1.1220784026251183 1.1195143213799041 1.0507329763066606 1.1063761111278192 1.0 17.668269287006467 -6.750529106021196 24.989755645682653 1.0853970445528547 0.9706821589403857 0.4592810085361574 0.061226251651773096 198.6224033015488 454939.8532835623 0.020456037195200866 0.020261916683567194 1.7761142307391822e-07 6.750529106021196 -0.11471488561246901 SPVPSPGS(ph)SSPQLQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SPVPSPGSSSPQLQVK 16 0 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 SPVPS(0.1)PGS(0.715)S(0.092)S(0.092)PQLQVK;SPVPSPGS(0.553)S(0.085)S(0.362)PQLQVK;SPVPSPGS(0.744)S(0.128)S(0.128)PQLQVK;S(0.357)PVPS(0.113)PGS(0.484)S(0.023)S(0.023)PQLQVK 197.1 6.4959e-12 72752000.0 94454.3 124026.0 114623.9 141548.0 139409.0 121259.0 136618.2 105724.0 103670.1 99594.0 True False 110443.54743253817 136338.48162072088 117356.96848956129 133617.52446480785 112092.80720587983 114899.9645757303 123676.73506588623 102948.85702383761 105186.07908793964 117649.6038143298 0.9387498457439435 1.158852025000315 0.9975126535467952 1.1357243894818212 0.9527682505653015 0.9766285720524917 1.0512295074199163 0.8750463553307637 0.8940623315140132 1.0 16.844136936723935 -6.98590433106678 0.9509243256180533 0.9292418558724148 1.0565504791530884 0.23912953892718702 0.0778299772998855 0.7157087742518458 1.3442082659627679 0.04999438087592788 0.03665213115274455 1.0329889335549769e-07 6.98590433106678 0.1273086232806736 SPVPSPGS(ph)SSPQLQVK ddPTM_PC-9_Lapatinib_30min_R1 3 SPVPSPGSSSPQLQVK 16 0 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 SPVPSPGS(0.895)S(0.052)S(0.052)PQLQVK;SPVPSPGS(0.644)S(0.069)S(0.287)PQLQVK;SPVPSPGS(0.738)S(0.13)S(0.131)PQLQVK 224.67 1.3435e-28 384973400.0 93651.0 111748.0 121686.0 101085.0 122192.0 119833.0 112932.0 120205.0 120715.0 90373.0 True False 92315.51956651012 111489.25437177646 111681.44680154357 108519.12810967471 115004.90679871515 114708.02193436657 118779.06637948022 125790.16312992708 107118.80551469579 105993.85263554675 0.8709516379589605 1.0518464193874084 1.0536596606744097 1.0238247352213055 1.085014875288592 1.082213912242467 1.120622219364878 1.1867684776252894 1.0106133785231595 1.0 16.69362106913671 -3.988105904427939 1.1802681062240354 1.0825367034605409 1.9797596014033545e-20 0.5437002260141952 0.05350856095007515 6.378451315345332 1.8977197062910764 0.016067461083953453 13.349171107881897 0.00010277656428471414 3.988105904427939 -1.0825367034605409 SPVPSPGSS(ph)SPQLQVK ddPTM_PC-9_AZD4547_30min_R2 1 SPVPSPGSSSPQLQVK 16 0 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 SPVPSPGS(0.113)S(0.443)S(0.443)PQLQVK 184.92 7.103799999999999e-08 170390000.0 16692.0 14148.0 21545.0 26139.0 24603.0 25009.0 21116.0 25104.0 21787.0 19868.0 True False 21999.708784831495 18721.06432078069 21259.299222747082 20113.05739352428 21187.29812869292 23445.18327650281 22995.283092887672 21224.753632531058 22938.616340957964 19172.427367348533 1.1474660126916398 0.9764576994910653 1.1088475556805384 1.0490616033198634 1.1050921055920024 1.2228594130147006 1.1993934128575512 1.10704571861765 1.1964377750113901 1.0 14.226745383699003 -6.528420618620081 24.713315788911835 1.1561999898515325 1.0678098418596875 0.18650668761963085 0.07174170260384088 174.79463543639073 779467.5778982202 0.022220372925928385 0.022290336566833855 2.9619613102625703e-07 6.528420618620081 -0.08839014799184497 SPVPSPGSS(ph)SPQLQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPVPSPGSSSPQLQVK 16 0 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 SPVPS(0.001)PGS(0.052)S(0.474)S(0.474)PQLQVK 189.52 3.0982e-08 190350000.0 29835.0 31933.0 35193.0 35985.0 38267.0 29268.0 37936.0 28595.0 29408.0 25491.0 True False 34885.47623188969 35103.09720215511 36032.134590195754 33968.87711494407 30768.856051957988 27733.13455663068 34342.42744714438 27844.41154890691 29838.036365529984 30112.316513355014 1.1585118739176956 1.1657388493039602 1.196591254419608 1.1280725313802626 1.021803023301505 0.9209897400065801 1.1404777653659852 0.9246851379420686 0.9908914298339224 1.0 14.878066077109773 -6.207578704590441 3.0493350680656315 0.9972203452708469 1.1715633950035558 0.6648459995661242 0.05727959247755802 0.15686126871153927 2.907110773007028 0.017698149452796602 0.022951584671813127 6.200422669212767e-07 6.207578704590441 0.17434304973270887 SPVPSPGSS(ph)SPQLQVK ddPTM_PC-9_Lapatinib_30min_R1 1 SPVPSPGSSSPQLQVK 16 0 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 SPVPSPGS(0.177)S(0.602)S(0.221)PQLQVK 200.81 2.4007e-12 48104000.0 26010.0 29491.0 31642.0 28818.0 35179.0 28939.0 30971.0 29686.0 32260.0 25320.0 True False 25639.09263035018 29422.71540142165 29040.516901652176 30937.371854029843 33109.84038457509 27701.346430103866 32574.526837733163 31065.319934071093 28626.539087139845 29696.528263220727 0.8633700344731644 0.9907796339231278 0.9779094931315246 1.0417841297747221 1.1149397697636516 0.9328143069306892 1.0969136374798683 1.0460926495756617 0.9639692166506187 1.0 14.858006659053697 -3.930693718047536 1.0680548159580272 1.0299527142691125 0.15295696919107912 0.4412580816116273 0.05361392720925848 8.154445254264656 1.988253317608721 0.01623552536147571 12.530732381366835 0.00011730223364824746 3.930693718047536 -0.8769957450780334 SPVPSPGSSS(ph)PQLQSSCK ddPTM_PC-9_AZD4547_30min_R2 1 SPVPSPGSSSPQLQSSCK 18 0 H0Y6J8 H0Y6J8 MICALL1 1 SPVPSPGSS(0.005)S(0.99)PQLQS(0.005)SCK 227.41 1.8035999999999996e-96 0.0 4498.7 6012.8 11206.0 12091.0 11958.0 12419.0 11520.0 14275.0 11186.0 13058.0 True False 5929.193021227025 7956.320013287402 11057.401118129668 9303.606754087836 10297.838110104856 11642.437966767498 12545.257682802894 12069.12675686666 11777.26912332839 12600.843394545873 0.4705393786413858 0.6314117050872327 0.8775127800505588 0.738332067368982 0.8172340364583973 0.9239411682401188 0.9955887308489971 0.9578030913463015 0.9346413374541296 1.0 13.621232678386392 -4.42249542506488 0.4591034349434588 0.9768028951257713 1.5793206405898412e-15 0.8705806291688638 0.05929639444997245 2.484130864799323 0.31754216481615277 0.0433957690313991 1.411176763552956 3.7801111931703096e-05 4.42249542506488 -0.9768028951257698 down SPVPSPGSSS(ph)PQLQSSCK ddPTM_PC-9_Lapatinib_30min_R1 2 SPVPSPGSSSPQLQSSCK 18 0 H0Y6J8 H0Y6J8 MICALL1 1 SPVPSPGSS(0.01)S(0.989)PQLQSSCK;SPVPSPGSS(0.27)S(0.73)PQLQSSCK 241.79 3.4441999999999996e-44 8660800.0 19274.7 31047.0 33219.0 27320.0 34493.0 31494.0 29132.0 31175.0 31867.0 22297.0 True False 18999.83924345292 30975.11257902201 30487.86204904824 29329.203936848357 32464.18955584719 30147.07503609979 30640.312416029265 32623.50430993282 28277.80288561331 26151.006741115038 0.7265433194042608 1.1844711328196185 1.1658389426788196 1.1215324988133824 1.241412610888378 1.1528074362315877 1.1716685601956605 1.2475047187625714 1.081327505497312 1.0 14.67457886684219 -4.759687767100304 24.99604100288222 1.1625142407916647 0.7265427745754127 0.768237567189452 0.06985785781662247 18.927950594204475 270029.0121618079 0.01590017907416951 0.09925406027971329 1.7390506574022945e-05 4.759687767100304 -0.43597146621625193 SPVPSPGSSS(ph)PQLQVK ddPTM_PC-9_AZD4547_30min_R2 1 SPVPSPGSSSPQLQVK 16 0 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 SPVPSPGS(0.257)S(0.154)S(0.589)PQLQVK 240.66 1.5360999999999996e-37 73879000.0 44463.0 36943.0 69931.0 85822.0 68347.0 75793.0 76832.0 85701.0 65541.0 65840.0 True False 58601.30911214733 48884.10229026019 69003.66924789627 66037.06383668237 58858.198805095875 71053.65172841704 83669.89915669382 72457.87966306337 69005.3634553966 63534.9616401363 0.9223474383138325 0.7694047659482512 1.0860739892900992 1.0393815016481482 0.9263907191519256 1.118339413359007 1.3169111461906964 1.1404410704371983 1.0861006550416257 1.0 15.955263067570753 -5.645476768212382 0.732339277215822 1.1399406867763682 0.8160398275930407 0.40465660097971257 0.10876934562276472 1.1008528918656133 0.9438622048283327 0.055990489895578296 0.24606430513332325 2.2621595466134083e-06 5.645476768212382 -0.32390085918332745 SPVPSPGSSS(ph)PQLQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPVPSPGSSSPQLQVK 16 0 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 SPVPSPGS(0.019)S(0.222)S(0.758)PQLQVK;SPVPSPGS(0.189)S(0.189)S(0.621)PQLQVK 224.36 1.3951e-28 214874000.0 86175.0 94778.0 114323.0 112344.0 128386.0 94634.0 112331.0 96781.0 88437.0 82641.0 True False 100762.72546616713 104186.93347401921 117048.89389239199 106049.72990416245 103229.68492661238 89671.22644636418 101690.19447398694 94240.60129794554 89730.22381863368 97623.15911420385 1.03216005690095 1.0672358323513866 1.198986950990421 1.0863173335755385 1.0574302846095132 0.918544608267213 1.0416605587924612 0.9653508670795907 0.9191489461395459 1.0 16.574935818073214 -6.575979456443041 4.803255970899962 0.9715445530226179 1.098650468136588 0.5753859466574726 0.052040353283906104 0.15345238720651938 7.536926824866807 0.018019081880303083 0.018235724579295537 2.654731136517014e-07 6.575979456443041 0.12710591511397018 SPVPSPGSSS(ph)PQLQVK ddPTM_PC-9_Lapatinib_30min_R1 1 SPVPSPGSSSPQLQVK 16 0 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 SPVPSPGS(0.027)S(0.38)S(0.593)PQLQVK 226.08 1.1096e-28 46004000.0 32596.0 41488.0 42872.0 35812.0 37256.0 39696.0 36263.0 37999.0 35450.0 30838.0 True False 32131.17506262568 41391.937085015095 39347.229650705805 38445.7339453299 35064.675328114216 37998.29461589564 38140.52070377829 39764.5722621696 31457.247694950664 36168.307210947896 0.8883792895040383 1.1444256111739186 1.087892486126519 1.0629674682063264 0.9694862168583986 1.0505964350024604 1.0545287751878367 1.099431389759185 0.8697461982801554 1.0 15.142438456516855 -8.257184707799977 24.998475010560732 0.9348730988833878 1.0481006668478912 0.2626336393380949 0.07344350370364525 426.1010517133488 2503611.010501863 0.05149257227896351 0.01791915078032034 5.531148164505654e-09 8.257184707799977 0.1132275679645034 SPVREPIDNLT(ph)PEER ddPTM_PC-9_Lapatinib_30min_R1 1 SPVREPIDNLTPEER 15 1 G3XAC6;Q14498-2;Q14498;Q5QP23;Q5QP22;H0Y4X3;Q14498-3 G3XAC6 RBM39 RNA-binding protein 39 1 S(0.008)PVREPIDNLT(0.992)PEER 93.71600000000001 0.032857 6035800.0 5380.6 4067.7 4466.7 3484.6 3741.4 3143.0 3476.9 4032.0 4519.5 3799.5 True False 5303.871657318805 4058.281490568741 4099.465167960617 3740.8691082848363 3521.3382078754134 3008.5812166908504 3656.916869397641 4219.341439539668 4010.466317555135 4456.238512484486 1.190212696753015 0.9106966512674672 0.9199384540292577 0.8394678825660951 0.7902041594071145 0.6751391803338365 0.8206286219089294 0.9468392294799451 0.8999667110096359 1.0 12.12161073717165 -3.8199461197482236 1.1701246830706442 0.8435014626275017 3.501200362889092 0.5601694899477037 0.08634460173641312 9.485599833791172 1.9680672259218521 0.027529731885278436 52.23222799257167 0.00015137490383426477 3.8199461197482236 2.6576989002615905 SPVS(ph)PLAAQGIPLPAQLTK ddPTM_PC-9_AZD4547_30min_R2 1 SPVSPLAAQGIPLPAQLTK 19 0 K7EIF1;K7EPF0;K7EQS3;K7EM48;K7EN63;Q96SI1-2;Q96SI1 K7EIF1 KCTD15 BTB/POZ domain-containing protein KCTD15 1 S(0.301)PVS(0.699)PLAAQGIPLPAQLTK 140.35 0.00017305 7737600.0 21850.0 25637.0 36807.0 41751.0 42266.0 42904.0 38464.0 46737.0 37948.0 39684.0 True False 28797.8454917666 33923.65889114043 36318.91513073344 32125.951996519834 36398.09546426593 40221.20609760795 41887.2214853586 39514.87055941695 39953.85380762254 38294.67523886954 0.7520065208057034 0.8858583779477395 0.9484064012604374 0.8389143345942681 0.9504740603550397 1.0503080610220965 1.093813205728471 1.0318633155376364 1.0433266128620649 1.0 15.224856183174037 -6.556334560375167 2.8908626562317066 1.049359473547941 0.8651697940522742 0.748902323286396 0.05095730144810126 0.13814451269836264 2.355850692052824 0.018173470148941894 0.01897315233996787 2.777572729859543e-07 6.556334560375167 -0.18418967949566678 SPVSFSPTDHSLSTS(ph)SGSSIFTPEYDDSR ddPTM_PC-9_AZD4547_30min_R2 1 SPVSFSPTDHSLSTSSGSSIFTPEYDDSR 29 0 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 S(0.001)PVS(0.002)FS(0.008)PT(0.007)DHS(0.043)LS(0.017)T(0.049)S(0.409)S(0.184)GS(0.105)S(0.075)IFT(0.088)PEY(0.005)DDS(0.006)R 49.699 0.008523600000000001 2512400.0 5169.8 2455.9 7882.1 10261.0 11892.0 8337.5 5849.3 9026.1 7814.0 9024.2 True False 6813.68886147986 3249.72164725794 7777.578203927348 7895.484980869677 10241.00107086193 7816.154806983178 6369.87636840443 7631.323644143901 8227.03208740283 8708.265504752706 0.7824392650592884 0.3731766843218481 0.8931259846961008 0.9066656243497125 1.1760092828213269 0.8975558683548818 0.7314747540630158 0.8763310718970336 0.9447383159037545 1.0 13.088169678930369 -5.375102809340366 7.134287982156907 0.9258940385008363 0.5796325196844409 0.5041832376386796 0.13925152280579167 0.19320541504773925 10.708600388834277 0.037016754260082364 0.07765353356862116 4.215966881880331e-06 5.375102809340366 -0.34626151881639544 SPYEAENS(ph)GEELDQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPYEAENSGEELDQR 15 0 R4GMT1;Q9NPC7-3;Q9NPC7-2;Q9NPC7 R4GMT1 MYNN Myoneurin 1 SPYEAENS(1)GEELDQR 69.37899999999999 0.025874 5473500.0 3340.9 3695.0 4588.0 4161.6 5606.5 6272.7 4192.0 5742.2 4093.2 4214.6 True False 3906.448384217208 4061.815180595718 4697.395320086891 3928.43904408924 4507.946571597005 5943.748569542746 3794.903412548217 5591.4733343638145 4153.055306426388 4978.673617244757 0.7846363679447362 0.815842831417329 0.9435033668036411 0.7890533395244481 0.9054513145795934 1.1938417792552687 0.762231811983761 1.1230849347096157 0.8341690228580853 1.0 12.28154572561007 -6.526418768960833 24.99213875462624 0.9846995750366995 0.8408098916082567 0.2451730433715107 0.12340175626190952 150.33145083653636 1061308.0142535092 0.03797830508378577 0.03815251683963823 2.97564577572532e-07 6.526418768960833 -0.14388968342844277 SPYEAENS(ph)GEELDQR ddPTM_PC-9_Lapatinib_30min_R1 2 SPYEAENSGEELDQR 15 0 R4GMT1;Q9NPC7-3;Q9NPC7-2;Q9NPC7 R4GMT1 MYNN Myoneurin 1 SPYEAENS(1)GEELDQR;SPYEAENS(1)GEELDQR 104.26 0.0011699000000000002 9135600.0 16022.599999999999 14618.4 14935.1 13541.2 11267.0 14780.0 12964.900000000001 13211.7 17191.0 14874.0 True False 15794.114785815023 14584.55199295181 13707.193729153201 14537.065020118995 10604.29721177428 14147.89385386278 13636.159084257093 13825.563813682109 15254.768550744617 17444.951081640815 0.9053688205773679 0.8360328397997454 0.7857398776875187 0.833310735701512 0.6078719947191089 0.8110022084700553 0.7816679462407825 0.792525226868204 0.874451781455486 1.0 14.090521931545872 -8.590153545547887 2.156466917453768 0.9996995809427136 0.7899454831247948 0.4414544184499454 0.07148364924839468 0.3661373467902921 3.874019976958738 0.07064941949486432 0.019480238132352598 2.5694871756260313e-09 8.590153545547887 -0.20975409781791876 SPYGGGRPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SPYGGGRPGR 10 1 P46781 P46781 RPS9 40S ribosomal protein S9 0 83.99799999999999 0.016624 1282400.0 850.55 766.47 764.16 1086.9 1973.0 2110.5 1002.1 1194.1 467.66 0.0 False True 994.5313158717547 842.560076176239 782.3804724929383 1026.0045167773435 1586.4048132990072 1999.8216646770895 907.1738334242771 1162.756140253531 474.4986427742024 0.0 0.0 SPYGSRS(ph)PFEHSVEHK ddPTM_PC-9_Lapatinib_30min_R1 1 SPYGSRSPFEHSVEHK 16 1 O14646 O14646 CHD1 Chromodomain-helicase-DNA-binding protein 1 1 S(0.002)PY(0.038)GS(0.049)RS(0.91)PFEHSVEHK 78.615 0.004052900000000001 8991900.0 46851.0 28569.0 46387.0 28369.0 39544.0 53270.0 32529.0 31654.0 52274.0 31055.0 True False 46182.89614857885 28502.85023577413 42573.239918998166 30455.350896209777 37218.099666495276 50991.76627843507 34213.192454380594 33124.76039860832 46386.35165037662 36422.81537181359 1.2679661271961493 0.7825548339635366 1.1688618654104423 0.8361613616441679 1.0218347836805919 1.3999951886722055 0.9393340988367707 0.9094508499813135 1.273552062817019 1.0 15.152554822072062 -6.54434366807807 24.992176224929416 1.1020894645729924 0.9985026592117989 0.048939141523618335 0.19151747350544127 739.3823630906485 860876.6966903532 0.06130589121850034 0.06131048782895836 2.8553301550256325e-07 6.54434366807807 -0.10358680536119347 SPYQEFTDHLVK ddPTM_PC-9_AZD4547_30min_R2 2 SPYQEFTDHLVK 12 0 H0YEN5;P15880;E9PQD7 H0YEN5 RPS2 40S ribosomal protein S2 0 ; 88.163 0.006869199999999999 9319400.0 47721.0 48263.0 67620.0 91682.0 74032.0 79175.0 55341.0 72157.0 58406.0 69762.0 False True 62895.285341537456 63863.07091559508 66723.31461787687 70546.13137277993 63753.934685338885 74224.17473378038 60266.24179027735 61006.7936529057 61493.22192178778 67319.65361390029 0.9342782079994352 0.9486541817619887 0.9911416805641393 1.047927723713264 0.9470330172966733 1.1025632300409585 0.8952250725460279 0.906225602448865 0.9134512526530669 1.0 16.038740133002904 -10.366590462243737 5.002047575285369 1.000000018816702 0.9675961888280779 0.025914315254260023 0.06249078400326424 3.8651784642495195e-08 8.900515579971778e-09 0.06289969616608147 0.015255392005002259 4.299416687370658e-11 10.366590462243737 -0.03240382998862412 SPYQEFTDHLVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SPYQEFTDHLVK 12 0 H0YEN5;P15880;E9PQD7 H0YEN5 RPS2 40S ribosomal protein S2 0 ; 155.66 0.00027737 10086800.0 63798.0 63663.0 62812.0 72451.0 79851.0 67541.0 75413.0 72615.0 68216.0 55873.0 False True 74597.74133206293 69983.0419058905 64309.67629583652 68391.80535931124 64204.76976519967 63999.03106086479 68269.33469716083 70708.93319195241 69213.5299480071 66002.33260957524 1.130228862869624 1.0603116456483805 0.9743545985904571 1.0362028530699132 0.9727651618767972 0.9696480189486543 1.0343473025566479 1.0713096097711912 1.0486527856133072 1.0 16.01022939166902 -4.900196442489454 3.326859535660903 1.0144493927752243 1.1329189040296332 0.5417656369943007 0.03315612313930382 0.22588853197967831 4.3609241566189185 0.009293003112630403 0.05828209696055022 1.2583560964352253e-05 4.900196442489454 0.11846951125440897 SPYQEFTDHLVK ddPTM_PC-9_Lapatinib_30min_R1 2 SPYQEFTDHLVK 12 0 H0YEN5;P15880;E9PQD7 H0YEN5 RPS2 40S ribosomal protein S2 0 ; 77.279 0.014888 19732600.0 97117.0 82209.0 83416.0 79644.0 85826.0 78424.0 75476.0 81593.0 88673.0 79194.0 False True 95732.09377092334 82018.65011140601 76557.85847507177 85501.28544459549 80777.88342040815 75069.98833527302 79383.77797309564 85384.10864989099 78685.71297191412 92882.57738062822 1.0306786963783094 0.8830358978444108 0.824243476377076 0.9205309311585469 0.869677454033003 0.8082246472084846 0.8546681219641961 0.9192693727693528 0.8471525574647218 1.0 16.5031203853733 -4.764001209439205 5.614439170139114 0.8737939105328081 1.0375761432095674 0.4148577544499674 0.05294497808651671 0.12903159793592617 13.50807412752037 0.012443204612112792 0.08190706633744024 1.7218637798699105e-05 4.764001209439205 0.1637822326767593 SQAAPGS(ph)SPCR ddPTM_PC-9_AZD4547_30min_R2 1 SQAAPGSSPCR 11 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 SQAAPGS(0.674)S(0.326)PCR 104.9 0.0026246 4308400.0 31574.0 35671.0 44805.0 62957.0 55338.0 44575.0 36251.0 50736.0 40360.0 47286.0 True False 41613.875220001784 47200.95316557593 44210.85642493307 48443.23632595386 47655.27390341052 41787.71820345127 39477.26877250766 42895.91699729504 42493.34720342695 45630.53153273825 0.9119743694010082 1.034416027604477 0.9688876052915005 1.06164085095519 1.044372535288562 0.9157841646764536 0.8651503159498406 0.9400705088547736 0.9312481309348658 1.0 15.47771183883771 -6.774512534468529 24.990482614685604 0.9226237409568364 1.0071565913904734 0.3437337031075284 0.0503355184167883 236.0875197854481 451299.19820896606 0.017529661132036287 0.015551061863238671 1.6806894174879358e-07 6.774512534468529 0.08453285043363701 SQAAPGS(ph)SPCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQAAPGSSPCR 11 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 SQAAPGS(0.5)S(0.5)PCR 97.273 0.0054588 9579600.0 30825.0 29153.0 40664.0 31549.0 42109.0 38220.0 37181.0 37297.0 36043.0 26847.0 True False 36043.06367849844 32047.11717453507 41633.583979078765 29781.411813238054 33858.04373198577 36215.67591753535 33658.94651287101 36317.99326943803 36570.060688343205 31714.148579264944 1.1364979131763224 1.010499055159495 1.312776342553281 0.9390575862001689 1.067600589918486 1.1419406649691222 1.0613227225301451 1.1451669017273614 1.1531150078628662 1.0 14.952838990616323 -5.782940406618139 24.999995582906266 1.0808601361358385 1.1389822095347197 0.12625515395089104 0.09327881320866406 647.2553245852686 752584.3372096678 0.025979179336188922 0.03857116924277619 1.6483885659623375e-06 5.782940406618139 0.0581220733988812 SQAAPGSS(ph)PCR ddPTM_PC-9_AZD4547_30min_R2 3 SQAAPGSSPCR 11 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 SQAAPGS(0.202)S(0.798)PCR;SQAAPGS(0.041)S(0.959)PCR;SQAAPGS(0.151)S(0.849)PCR 105.58 0.0025404 75755200.0 68125.0 56071.0 76704.0 115637.0 99372.0 89298.0 82309.0 99645.0 77183.0 91158.0 True False 89787.33291197264 74194.85422183307 75686.85484249672 88978.67622384042 85575.91308557788 83714.18194350618 89634.34154633911 84247.15486430682 81262.73580778255 87966.58616633585 1.0206981630751697 0.8434436012048729 0.8604045938463565 1.0115053920086294 0.9728229412445601 0.9516588694849564 1.0189589644509986 0.9577176804952284 0.9237909455088208 1.0 16.42466800413564 -5.763911195954505 24.99998167733492 0.975438451147916 0.901708267863762 0.267231033440257 0.05158614286993086 79.55633209767807 804647.2087263326 0.014197989996737886 0.022232007024513972 1.7222206967283409e-06 5.763911195954505 -0.07373018328415404 SQAAPGSS(ph)PCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQAAPGSSPCR 11 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 SQAAPGS(0.244)S(0.756)PCR;SQAAPGS(0.038)S(0.962)PCR 114.21 0.0014807 39187200.0 38149.0 36369.0 42748.0 46110.0 49395.0 42081.0 46773.0 44744.0 39081.0 30260.0 True False 44606.87222290464 39979.473965652454 43767.27444269277 43526.606190636965 39716.40433497437 39874.19828063328 42342.32283280482 43569.51741018675 39652.48569101188 35745.898461971796 1.247887845660379 1.1184352802933333 1.2243998983339164 1.2176671468180513 1.1110758448896338 1.1154901679993683 1.1845365385863953 1.2188675983774222 1.1092877056425396 1.0 15.125490093942897 -14.52287874286324 0.22083713565640312 0.12161299582250568 1.1928705566145754 0.5453236317547367 0.04921191860675 125.17238036992204 1.2492715544574122 48.879804121533624 0.09534669569677781 3.00000001669672e-15 14.52287874286324 1.0712575607920698 SQAAPGSS(ph)PCR ddPTM_PC-9_Lapatinib_30min_R1 4 SQAAPGSSPCR 11 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 SQAAPGS(0.092)S(0.908)PCR;SQAAPGS(0.233)S(0.767)PCR;SQAAPGS(0.037)S(0.963)PCR;SQAAPGS(0.393)S(0.607)PCR 131.08 0.00017663 74259900.0 97874.0 90772.0 101051.0 82791.0 89932.0 77630.5 70678.0 69852.2 83542.0 59468.8 True False 96478.2988121066 90561.82301101499 92742.97684814011 88879.72632267959 84642.37657311485 74310.42448053411 74337.36100989002 73097.7882199931 74132.6202237396 69747.90284280505 1.3832430063101024 1.2984164300268568 1.3296883930282521 1.2742996233591861 1.2135472626880028 1.06541446339988 1.0658006618124205 1.0480284745584092 1.0628652217804548 1.0 16.08986221865944 -6.518183943469874 1.2691667807562417 1.0399268951763319 1.3379369720543568 0.9573724965932299 0.027477478184795352 0.07889448037782974 0.2645007864085738 0.011531667084806324 0.013019016517450728 3.032606465348582e-07 6.518183943469874 0.29801007687802494 SQAGHTLHHQES(ph)RR ddPTM_PC-9_AZD4547_30min_R2 1 SQAGHTLHHQESRR 14 1 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 SQAGHTLHHQES(1)RR 74.428 0.004358399999999999 450420.0 0.0 0.0 578.1 919.48 809.29 705.61 432.08 532.33 478.69 0.0 True False 0.0 0.0 570.4340162761705 707.5080918243885 696.9340528622484 661.4880951550705 470.5342829501282 450.0706302264681 503.9925761349965 0.0 0.0 SQAGS(ph)TPLTR ddPTM_PC-9_AZD4547_30min_R2 1 SQAGSTPLTR 10 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 S(0.001)QAGS(0.995)T(0.004)PLTR 89.663 0.02254 0.0 11646.0 12018.0 20434.0 29053.0 20165.0 15952.0 13760.0 15649.0 16122.0 13791.0 True False 15349.185748151665 15902.5834752009 20163.031808661588 22355.27971437549 17365.437823236698 14954.518918260343 14984.613343347904 13230.806628245638 16974.176006284666 13308.181287653706 1.153364642123672 1.1949479144798003 1.5150854480294222 1.6798147869472575 1.3048693467489054 1.1237086867860735 1.125970034481681 0.9941859328682388 1.2754692500343368 1.0 13.700025803799726 -6.692232288874082 3.9902195437306127 1.1030186784873879 1.3924012543969244 0.4208717489376469 0.15754000972246127 0.237408168006045 7.438238555398577 0.05922352533808544 0.057791676456207655 2.0312702651663775e-07 6.692232288874082 0.28938257590953653 SQANGAGALSYVS(ph)PNTSK ddPTM_PC-9_AZD4547_30min_R2 4 SQANGAGALSYVSPNTSK 18 0 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;A0A494C002;A0A494C1N1;A0A494C0Q2;F5H1Z4;A0A494C1K5;A0A494C0P9;A0A494BZU6;A0A494C1G3;A0A494C156;A0A494BZW7 O95453 PARN Poly(A)-specific ribonuclease PARN 1 SQANGAGALS(0.001)YVS(0.791)PNT(0.204)S(0.004)K;SQANGAGALS(0.001)YVS(0.999)PNT(0.001)SK;SQANGAGALSYVS(0.94)PNT(0.059)S(0.001)K;SQANGAGALSYVS(0.997)PNT(0.002)SK 246.67 1.6948e-53 172616000.0 336745.0 303957.0 371037.0 409869.0 415863.0 408904.0 362822.0 398026.0 366967.0 403885.0 True False 443822.90526887716 402205.15604690026 366116.8069487311 315380.0344629248 358127.6007678987 383335.1682392385 395112.45512065245 336520.2274275734 386364.1264420215 389745.10908302676 1.1387516993172333 1.0319697327137443 0.9393749874375917 0.809195618143703 0.9188764462252876 0.983553505369524 1.0137714262797388 0.8634366912757975 0.9913251441462348 1.0 18.572171393072672 -4.968750856296348 2.508391741366218 0.9341213298768849 1.1464724159700508 0.5108001452635337 0.0611860130464856 0.2928313399965069 3.1061392163453094 0.016892196843608206 0.11274714267135778 1.0746057095243037e-05 4.968750856296348 0.2123510860931659 SQANGAGALSYVS(ph)PNTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SQANGAGALSYVSPNTSK 18 0 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;A0A494C002;A0A494C1N1;A0A494C0Q2;F5H1Z4;A0A494C1K5;A0A494C0P9;A0A494BZU6;A0A494C1G3;A0A494C156;A0A494BZW7 O95453 PARN Poly(A)-specific ribonuclease PARN 1 SQANGAGALSYVS(0.878)PNT(0.115)S(0.008)K;SQANGAGALSYVS(0.767)PNT(0.232)S(0.001)K;SQANGAGALS(0.18)Y(0.007)VS(0.501)PNT(0.3)S(0.012)K 238.49 1.6139999999999998e-43 74688000.0 90363.0 87984.2 91961.6 91884.4 112040.0 91228.7 107686.8 95542.6 83203.3 83788.5 True False 105659.67114939692 96718.68990867936 94154.31331031003 86736.41496124397 90086.56628586966 86444.50637305221 97485.92671908326 93034.70798575266 84419.99085732116 98978.69178059897 1.067499168241255 0.9771667837666592 0.9512584134675887 0.8763140166926854 0.9101612141485965 0.8733648103237145 0.9849183189365178 0.9399468341325218 0.8529107562307517 1.0 16.594830353517196 -4.80274821960049 1.5601324015300377 0.9183141154493488 1.1185795464552897 0.49388071192076954 0.04512917553111609 0.8422893744425383 2.017672960020152 0.012581835140793808 0.25807548409411046 1.5748956389757234e-05 4.80274821960049 0.20026543100594085 SQANGAGALSYVS(ph)PNTSK ddPTM_PC-9_Lapatinib_30min_R1 4 SQANGAGALSYVSPNTSK 18 0 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;A0A494C002;A0A494C1N1;A0A494C0Q2;F5H1Z4;A0A494C1K5;A0A494C0P9;A0A494BZU6;A0A494C1G3;A0A494C156;A0A494BZW7 O95453 PARN Poly(A)-specific ribonuclease PARN 1 SQANGAGALS(0.001)YVS(0.573)PNT(0.366)S(0.059)K;SQANGAGALS(0.001)Y(0.001)VS(0.622)PNT(0.289)S(0.087)K;SQANGAGALSYVS(0.862)PNT(0.12)S(0.017)K;SQANGAGALSYVS(0.875)PNT(0.11)S(0.016)K 162.39 1.996e-06 117002000.0 204773.0 201262.0 206317.0 196969.0 225340.0 185423.0 174250.0 170764.0 189508.0 164135.0 True False 201852.89946923067 200795.99020450085 189354.41266665113 211454.75732932187 212085.94423548548 177492.89053212447 183271.81238820188 178698.3188446312 168163.61343229064 192505.51605386013 1.0485564445475697 1.0430661641317394 0.9836311008027044 1.098434796383497 1.1017135954491146 0.9220145696109021 0.9520340826853252 0.9282763554402987 0.8735521811501807 1.0 17.554540259826346 -6.773082487713186 24.99947818515088 0.9317463478795127 1.0528521313490797 0.6666074894555283 0.04234910314280101 137.99084775188246 296284.93856880633 0.015245285607829102 0.013554625391293618 1.686232720395249e-07 6.773082487713186 0.12110578346956702 SQANGAGALSYVSPNT(ph)SK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQANGAGALSYVSPNTSK 18 0 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;A0A494C002;A0A494C1N1;A0A494C0Q2;F5H1Z4;A0A494C1K5;A0A494C0P9;A0A494BZU6;A0A494C1G3;A0A494C156;A0A494BZW7 O95453 PARN Poly(A)-specific ribonuclease PARN 1 SQANGAGALSYVS(0.234)PNT(0.748)S(0.018)K;SQANGAGALSYVS(0.288)PNT(0.7)S(0.011)K 220.16 1.6366e-27 74301000.0 179387.0 189040.0 184117.0 196328.0 235131.0 199101.0 225512.0 209060.0 179381.0 156692.0 True False 209753.67604524878 207806.641878164 188507.0475476112 185328.37866396434 189058.76845200628 188659.793062721 204149.8707945067 203572.39651737962 182004.10776948862 185099.01922681008 1.13319712293142 1.122678244035044 1.0184119199282473 1.0012391175172743 1.021392599710883 1.01923712967678 1.102922487905529 1.0998026751721104 0.9832796982380057 1.0 17.497937725342943 -5.251893880494092 21.956008928188652 1.0351232460663586 1.1279377933214803 0.5055096352234776 0.03824289156577057 114.51294554201489 263386.2163780001 0.010455928154996654 0.02670332733030566 5.598943945249167e-06 5.251893880494092 0.09281454725512162 SQANGAGALSYVSPNT(ph)SK ddPTM_PC-9_Lapatinib_30min_R1 1 SQANGAGALSYVSPNTSK 18 0 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;A0A494C002;A0A494C1N1;A0A494C0Q2;F5H1Z4;A0A494C1K5;A0A494C0P9;A0A494BZU6;A0A494C1G3;A0A494C156;A0A494BZW7 O95453 PARN Poly(A)-specific ribonuclease PARN 1 SQANGAGALSYVS(0.359)PNT(0.629)S(0.012)K 113.05 0.00040139 61862000.0 63118.0 55883.0 60710.0 63572.0 68131.0 63008.0 52544.0 58175.0 54758.0 57722.0 True False 62217.92574557642 55753.606346941255 55718.658147377006 68247.2969499751 64123.66853069968 60313.29471882179 55264.47122023348 60878.0228782788 48590.57741269699 67699.17079026974 0.91903527058442 0.8235493241071514 0.8230330962249442 1.0080964973914297 0.9471854349494638 0.8909015282575735 0.8163241968124154 0.899243257600264 0.717742578608966 1.0 16.046850542683664 -10.220746801834574 10.536067433141879 0.9999983483297046 0.8748137320280331 0.19921582067671983 0.07695113322016602 0.0 0.0 0.07616244303201786 0.01847210572506456 6.015243301667613e-11 10.220746801834574 -0.12518461630167144 SQAPLES(ph)SLDSLGDVFLDSGRK ddPTM_PC-9_AZD4547_30min_R2 1 SQAPLESSLDSLGDVFLDSGRK 22 1 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 S(0.023)QAPLES(0.722)S(0.255)LDSLGDVFLDSGRK 91.617 0.00079575 0.0 3242.4 3518.7 4289.3 7346.9 4455.7 4152.1 3310.0 3683.3 3374.4 3235.5 True False 4273.415753890344 4656.0509630711795 4232.421079421167 5653.185713473488 3837.1029659804503 3892.468530623671 3604.5835876803458 3114.1306188138005 3552.7638950258643 3122.226129809556 1.368707959071179 1.491260007921073 1.3555780085920068 1.810626610129072 1.2289638246716292 1.2466965456025754 1.1544915191329246 0.99740713495462 1.1378944853179387 1.0 11.608359314143376 -6.776995505640793 1.7347654261775811 1.0759906224717395 1.4903502782856988 0.6437917544680947 0.13839401908109675 0.22680134072919608 1.4117604038789813 0.05807035362877695 0.05236666093687215 1.6711079079229072e-07 6.776995505640793 0.4143596558139593 SQAPLESSLDSLGDVFLDS(ph)GRK ddPTM_PC-9_AZD4547_30min_R2 1 SQAPLESSLDSLGDVFLDSGRK 22 1 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 SQAPLESSLDS(0.007)LGDVFLDS(0.992)GRK 55.588 0.005931399999999999 905050.0 3498.7 2853.2 2599.1 3537.9 2244.9 2578.5 2125.2 3029.3 1878.4 2741.6 True False 4611.213822519168 3775.4411026329867 2564.6342357782282 2722.29181501012 1933.2343847946472 2417.2659873830435 2314.338682942078 2561.1912913888764 1977.688389170397 2645.617418478095 1.7429632078744755 1.4270548251851278 0.9693896849430133 1.0289816645432175 0.730730895288235 0.9136869036693855 0.8747820704451716 0.9680883084229975 0.7475337799628158 1.0 11.369388733893578 -5.014893062480545 1.4486198020669643 0.8800050798120486 1.9068624501161968 0.9057508250889926 0.0910855938692158 0.19815102922486433 0.5241430693702753 0.025278751471952115 0.26096633762954113 9.662887816314745e-06 5.014893062480545 1.0268573703041484 SQASDDSS(ph)LGK ddPTM_PC-9_AZD4547_30min_R2 1 SQASDDSSLGK 11 0 O75140;H0Y770;A0A2R8Y6V4;A0A5F9UWT1;A0A2R8Y5T1;A0A2R8Y5K9;A0A2R8Y721;A0A2R8Y6H3;O75140-6;A0A2R8Y842;A0A2R8Y7U0;O75140-8;O75140-5;O75140-1;O75140-4;O75140-9;A0A2R8YEW8;A0A2R8Y5P2;A0A2R8Y7U6;A0A2R8YF97;A0A2R8Y6H8;A0A2R8YF50;O75140-2;A0A2R8Y5E9 O75140 DEPDC5 DEP domain-containing protein 5 1 SQAS(0.31)DDS(0.114)S(0.576)LGK 90.70700000000001 0.023518 0.0 10583.0 10678.0 14939.0 17442.0 19879.0 17334.0 16377.0 17790.0 15422.0 17127.0 True False 13948.173859925213 14129.454680329114 14740.8990990308 13421.016376213727 17119.14398651735 16250.102239789658 17834.521273547143 15040.964273531197 16237.17543536299 16527.388943053076 0.8439429790141183 0.8549114883793014 0.8919073151737505 0.8120469859127358 1.0358045088370116 0.9832225946748854 1.0790888588026781 0.9100629461408867 0.9824404502919336 1.0 14.0125711999781 -6.26224130897466 24.999985391387913 0.9972116258033625 0.853946076869461 0.7284501962052344 0.04416721640591987 39.76474170255071 1239655.1470700675 0.013444818615953322 0.016148000278664663 5.467121064058436e-07 6.26224130897466 -0.14326554893390153 SQASDDSS(ph)LGK ddPTM_PC-9_Lapatinib_30min_R1 1 SQASDDSSLGK 11 0 O75140;H0Y770;A0A2R8Y6V4;A0A5F9UWT1;A0A2R8Y5T1;A0A2R8Y5K9;A0A2R8Y721;A0A2R8Y6H3;O75140-6;A0A2R8Y842;A0A2R8Y7U0;O75140-8;O75140-5;O75140-1;O75140-4;O75140-9;A0A2R8YEW8;A0A2R8Y5P2;A0A2R8Y7U6;A0A2R8YF97;A0A2R8Y6H8;A0A2R8YF50;O75140-2;A0A2R8Y5E9 O75140 DEPDC5 DEP domain-containing protein 5 1 SQASDDS(0.388)S(0.612)LGK 91.441 0.022282 0.0 25799.0 21587.0 17756.0 20315.0 25151.0 25825.0 23662.0 23931.0 25917.0 21353.0 True False 25431.101529042848 21537.016627801317 16296.170220142101 21809.032868853374 23671.667628768526 24720.52495101531 24887.102580944804 25042.921624410672 22997.954541891013 25043.837598915958 1.0154634419983481 0.859972699580737 0.6507057936219605 0.870834303357621 0.9452092769437689 0.987090131589312 0.9937415734568595 0.9999634251539259 0.9183079250955731 1.0 14.61216803050652 -6.275730755305277 3.4000503158941586 0.9784354187516683 0.8333603628008636 0.3417773956186494 0.0854205451305409 0.27748682470661445 6.800271481315585 0.028489868135654267 0.034890201029158206 5.299919152243905e-07 6.275730755305277 -0.14507505595080472 SQAT(ph)SPGQTNGDSSLEVLATR ddPTM_PC-9_AZD4547_30min_R2 1 SQATSPGQTNGDSSLEVLATR 21 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;C9J760;A0A087WVI1;Q96JY6-2 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 S(0.172)QAT(0.669)S(0.159)PGQTNGDSSLEVLATR 190.57 1.5025999999999998e-52 0.0 14092.0 12658.0 19196.0 26173.0 21117.0 19803.0 18560.0 21471.0 17767.0 22495.0 True False 18572.962868191073 16749.450959318776 18941.448497556412 20139.219218819046 18185.26905595287 18564.715279482807 20211.804044515786 18153.150304496266 18706.127347950613 21707.456896945125 0.8556028905811087 0.7715989504821228 0.8725779619178711 0.9277558082657404 0.8377429535982205 0.8552229479306444 0.9310995820685093 0.8362633352528249 0.861737394516403 1.0 14.405903098728174 -14.522878745280314 0.2001912630849003 1.6163752182910716 0.8397119567288042 0.49074256875134037 0.042867799699422254 128.6116400654565 1.2691015604864375 31.816078010259403 0.10721164378844895 3.0000000000001608e-15 14.522878745280314 -0.7766632615622674 SQAT(ph)SPGQTNGDSSLEVLATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SQATSPGQTNGDSSLEVLATR 21 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;C9J760;A0A087WVI1;Q96JY6-2 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 S(0.005)QAT(0.558)S(0.437)PGQTNGDSSLEVLATR;SQAT(0.5)S(0.5)PGQTNGDSSLEVLATR;S(0.003)QAT(0.661)S(0.336)PGQTNGDSSLEVLATR 269.34 1.3906999999999995e-86 47622800.0 52934.0 54346.0 57205.0 62532.0 67809.0 58475.0 65799.0 67100.0 58993.0 41148.6 True False 61894.68070584381 59741.11171979839 58568.984151170625 59028.53477147935 54522.31322097944 55408.468060645675 59566.04237649337 65338.69609832675 59855.66102120883 48608.515447861624 1.273329994458135 1.229025638190448 1.2049120120525545 1.214366129629991 1.1216617647881277 1.1398922092174941 1.2254240193857595 1.3441820943577307 1.2313822067948381 1.0 15.568921453015312 -4.8200622974527185 1.4960113286468972 1.195012954808629 1.2998221510030599 0.09261169301131811 0.08444878923053371 3.1705041883893967 7.0187782348087975 0.02479466516150429 0.48735955114661383 1.5133441509326307e-05 4.8200622974527185 0.10480919619443085 SQATS(ph)PGQTNGDSSLEVLATR ddPTM_PC-9_AZD4547_30min_R2 2 SQATSPGQTNGDSSLEVLATR 21 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;C9J760;A0A087WVI1;Q96JY6-2 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 SQAT(0.034)S(0.966)PGQTNGDSSLEVLATR;SQAT(0.04)S(0.959)PGQTNGDSSLEVLATR 279.86 2.550599999999999e-101 94158000.0 60089.0 51547.0 73246.0 107421.0 95113.0 81632.0 67668.0 88711.0 68972.0 76215.0 True False 79196.05207115621 68208.55969347479 72274.71018191386 82656.74808790575 81908.20171988674 76527.53813537033 73690.32090971414 75002.75332598253 72617.71911087123 73546.73604804052 1.0768126000782086 0.9274179026642481 0.9827045232123452 1.1238669794117662 1.1136891468084258 1.040529359255083 1.0019522941382446 1.0197971705636393 0.9873683458017436 1.0 16.166373696667996 -10.500693674912128 12.554673813940722 1.0000002226763849 1.030363892407496 0.02425841448704491 0.057951297044871106 0.0 0.0 0.060804076650258936 0.014747154735127653 3.157230758011698e-11 10.500693674912128 0.030363669731111154 SQATS(ph)PGQTNGDSSLEVLATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SQATSPGQTNGDSSLEVLATR 21 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;C9J760;A0A087WVI1;Q96JY6-2 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 SQAT(0.019)S(0.981)PGQTNGDSSLEVLATR;S(0.002)QAT(0.239)S(0.759)PGQTNGDSSLEVLATR;SQAT(0.13)S(0.869)PGQT(0.001)NGDSSLEVLATR 266.35 1.1167999999999998e-86 39513600.0 77464.5 82312.5 98837.7 102794.0 106490.0 106731.0 99126.0 90807.0 95277.0 83791.4 True False 90577.70985638394 90483.94101563864 101194.36561206478 97034.78544264473 85624.04894486147 101133.8384708128 89736.06766990786 88423.41246796974 96670.24587862463 98982.1175276427 0.9150916561376689 0.9141443250127401 1.0223499773462037 0.9803264252812723 0.8650456373692882 1.021738481625928 0.906588684009991 0.893327145110588 0.9766435422199122 1.0 16.59488028570619 SQATS(ph)PGQTNGDSSLEVLATR ddPTM_PC-9_Lapatinib_30min_R1 4 SQATSPGQTNGDSSLEVLATR 21 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;C9J760;A0A087WVI1;Q96JY6-2 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 SQAT(0.102)S(0.898)PGQTNGDSSLEVLATR;SQAT(0.044)S(0.956)PGQTNGDSSLEVLATR;SQAT(0.041)S(0.959)PGQTNGDSSLEVLATR;SQAT(0.003)S(0.997)PGQTNGDSSLEVLATR 274.27 8.2466e-101 86005000.0 117791.0 97356.0 104059.0 89604.0 109960.0 98555.0 87448.0 84062.0 107919.0 75169.0 True False 116111.2787397762 97130.57816353478 95503.67069935588 96193.77707018136 103492.3689896777 94340.0323929261 91975.62955364991 87967.82740341837 95764.02578254938 88161.86149360352 1.3170239009551825 1.1017301191012394 1.0832764767141974 1.0911041967638193 1.173890469601603 1.0700775913150478 1.0432587061506533 0.9977991153215473 1.0862296253748842 1.0 16.427867065564214 SQATSPGQT(ph)NGDSSLEVLATR ddPTM_PC-9_AZD4547_30min_R2 1 SQATSPGQTNGDSSLEVLATR 21 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;C9J760;A0A087WVI1;Q96JY6-2 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 SQAT(0.048)S(0.332)PGQT(0.618)NGDS(0.001)SLEVLATR 106.3 0.00018486 6412900.0 8869.9 7129.8 14206.0 20033.0 18622.0 15164.0 8291.6 14701.0 11649.0 9211.9 True False 11690.343694618789 9434.368419161872 14017.619157964495 15414.701356764666 16036.656739117974 14215.792682829726 9029.536337042406 12429.298245372805 12264.742358095154 8889.394184884137 1.3150889083642496 1.0613061163610487 1.576892515555288 1.734055328874538 1.8040213321158953 1.5991857698247647 1.0157650959383229 1.3982165698657008 1.3797050848471302 1.0 13.117869386929215 -8.69076678270408 0.6752378012926882 1.0102107951074109 1.4820009647966597 0.23979858456023995 0.2426356301160465 1.6202500980411 1.5922460859646268 0.2815973693594782 0.10854539765923961 2.0381362685037377e-09 8.69076678270408 0.4717901696892488 SQCRNS(ph)PSNLSSSSDTGSVGGTYR ddPTM_PC-9_AZD4547_30min_R2 4 SQCRNSPSNLSSSSDTGSVGGTYR 24 1 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 S(0.035)QCRNS(0.862)PS(0.085)NLS(0.012)S(0.004)S(0.001)SDTGSVGGTYR;S(0.092)QCRNS(0.741)PS(0.163)NLS(0.003)S(0.001)SSDTGSVGGTYR;S(0.107)QCRNS(0.866)PS(0.027)NLSSSSDTGSVGGTYR;S(0.013)QCRNS(0.869)PS(0.118)NLSSSSDTGSVGGTYR 90.435 6.0519000000000005e-06 20675700.0 18603.7 14241.0 29927.4 48299.6 44287.3 30708.000000000004 24895.1 34948.1 23010.600000000002 27642.0 True False 24519.289619001298 18844.124752066564 29530.543121784216 37164.87344138127 38138.77284944365 28787.823905587935 27110.715671800914 29547.67417244497 24226.893338929054 26674.26199357 0.9192115465054602 0.7064534627653076 1.1070800432605312 1.393285911727946 1.4297967403423288 1.0792360033251314 1.0163623525305452 1.107722274736884 0.9082498081772272 1.0 14.703160735587133 -5.339189270015115 6.277902850198664 1.150099890243561 0.814395951855789 0.3732817106655033 0.1633167564805239 0.22724518175297817 14.755071386278525 0.04679843341509305 0.09929845324208125 4.5794226725567605e-06 5.339189270015115 -0.3357039383877721 SQCRNS(ph)PSNLSSSSDTGSVGGTYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQCRNSPSNLSSSSDTGSVGGTYR 24 1 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 S(0.055)QCRNS(0.8)PS(0.145)NLSSSSDTGSVGGTYR 73.831 0.0015865999999999999 0.0 3676.5 2224.9 1079.1 4315.8 4692.0 4333.3 4126.3 3591.5 3821.3 3055.2 True False 4298.8588358150655 2445.7733681481527 1104.8298365095395 4073.999718012387 3772.6362818038247 4106.054119661325 3735.426992175024 3497.2269305088003 3877.1792833106524 3609.083575050107 1.1911219971555749 0.6776715798592159 0.3061247581373065 1.128818336648196 1.0453169629776298 1.1376999269417911 1.0350070632884036 0.969006912083006 1.0742835965655972 1.0 11.81741683657395 SQCRNS(ph)PSNLSSSSDTGSVGGTYR ddPTM_PC-9_Lapatinib_30min_R1 1 SQCRNSPSNLSSSSDTGSVGGTYR 24 1 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 S(0.105)QCRNS(0.88)PS(0.016)NLSSSSDTGSVGGTYR 73.831 0.00015937 3776600.0 14799.0 10080.0 11671.0 9495.9 10573.0 9233.6 8130.0 5077.2 9841.1 6652.7 True False 14587.963546195771 10056.660379313358 10711.45543136283 10194.260163393781 9951.116927317782 8838.7004525729 8550.931619604487 5313.105247229865 8732.69168662282 7802.610330834459 1.8696260517517918 1.288884098129483 1.3728040972433493 1.3065191943660148 1.2753574131458065 1.1327876284740257 1.0959065308968208 0.6809394576880848 1.1192013078127012 1.0 12.9297411370145 -1.522878745280342 0.27705182897761615 0.9094153700716936 7.143425011729061 0.7188915648646717 0.15297562707802323 28.044035510871446 0.39431305503771585 0.1746136204004741 84.32529275035733 0.02999999999999969 1.522878745280342 6.234009641657368 SQDADS(ph)PGSSGAPENLTFK ddPTM_PC-9_AZD4547_30min_R2 2 SQDADSPGSSGAPENLTFK 19 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;H0Y8L4;H0Y948;H0Y8U8 A8MQ02 MLLT4 Afadin 1 S(0.021)QDADS(0.978)PGS(0.001)SGAPENLTFK;SQDADS(0.96)PGS(0.038)S(0.002)GAPENLTFK 160.05 1.8901e-20 0.0 27114.1 22808.9 32955.0 43319.0 37444.0 33473.0 29025.0 41410.0 29343.4 28100.3 True False 35735.81979168461 30181.4308726502 32517.995167585534 33332.473821878346 32245.546930487235 31379.928018488506 31608.168771124503 35011.03600713475 30894.432218261605 27116.517050065635 1.3178617196930207 1.1130275623866357 1.1991951292102547 1.2292313854443806 1.1891478124182318 1.1572256112594133 1.1656426491929572 1.291133221220607 1.1393215493428137 1.0 14.726884264613355 -8.538088479303026 22.703235403980663 0.9999999967348233 1.2022287607083886 0.5441284276980745 0.05788360819107135 574.1844854075506 857073.1235286345 0.05302262976104694 0.013690384134306144 2.896753368760074e-09 8.538088479303026 0.20222876397356526 SQDADS(ph)PGSSGAPENLTFK ddPTM_PC-9_Lapatinib_30min_R1 2 SQDADSPGSSGAPENLTFK 19 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;H0Y8L4;H0Y948;H0Y8U8 A8MQ02 MLLT4 Afadin 1 S(0.019)QDADS(0.79)PGS(0.168)S(0.023)GAPENLTFK;S(0.001)QDADS(0.997)PGS(0.002)SGAPENLTFK 147.64 3.412e-14 0.0 21475.6 25684.3 26333.7 21907.1 22523.6 22918.9 18054.3 21062.5 25875.8 16867.2 True False 21169.354005857283 25624.829581388694 24168.644837021613 23518.22121394327 21198.80613110138 21938.712073565348 18989.06331363164 22041.14064243658 22961.394919746246 19782.67304586875 1.0700957326026332 1.295316842267682 1.2217077429821241 1.1888292931603914 1.0715845165084181 1.1089862336953928 0.9598835945780927 1.1141639247300543 1.1606821214962817 1.0 14.271949756580163 -6.229919598719129 4.02175896207306 1.0706127953468523 1.20563599625217 0.40037694096834797 0.07447187034098966 0.22201195382577485 8.125573362069195 0.022793745113640202 0.028845433539790515 5.889526785386197e-07 6.229919598719129 0.13502320090531783 SQDAT(ph)FSPGSEQAEK ddPTM_PC-9_AZD4547_30min_R2 1 SQDATFSPGSEQAEK 15 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 S(0.011)QDAT(0.883)FS(0.03)PGS(0.075)EQAEK 231.41 1.2089000000000002e-24 9791200.0 33776.0 36932.0 32966.0 45100.0 46355.0 46193.0 36250.0 46421.0 41429.0 37146.0 True False 44516.065415556484 48869.54675537694 32528.849300398255 34702.89178805405 39919.40839554362 43304.54440767304 39476.17977444489 39247.70109845938 43618.85236102021 35845.529846362435 1.2418861042466618 1.3633372686869676 0.9074729663592697 0.9681232760903284 1.1136509508059231 1.2080877195365978 1.1012859886196071 1.0949120090197857 1.2168561198000147 1.0 15.129505596926084 -5.241310429563442 24.933014224619388 1.0827580995796013 1.3026117128837502 0.4667953396545368 0.09655325502898236 750.4304065210305 929528.0797148751 0.02604723307173252 0.06873727193240196 5.73706235853155e-06 5.241310429563442 0.21985361330414888 SQDAT(ph)FSPGSEQAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQDATFSPGSEQAEK 15 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 SQDAT(0.999)FS(0.001)PGSEQAEK 268.17 2.2023999999999998e-61 15127000.0 26908.0 31124.0 29639.0 35875.0 35594.0 27384.0 26674.0 29210.0 24806.0 24154.0 True False 31462.99294277489 34213.78502864984 30345.706166533444 33865.04005831927 28619.611213666925 25947.934833223135 24147.245616963526 28443.268450553267 25168.740821658615 28532.92899704122 1.1026906121708537 1.1990982430229196 1.0635328104478934 1.186875699365844 1.0030379712028406 0.909403126328666 0.8462939651049327 0.996857646598523 0.8820945380079465 1.0 14.800340231362544 -6.468817427327064 3.672807929848457 0.9230372443251302 1.1363933665247388 0.7521759380793709 0.05704169514195605 0.11005441321458592 2.9874902845043825 0.017891694632393797 0.019719246778153076 3.3976807737290005e-07 6.468817427327064 0.21335612219960853 SQDAT(ph)FSPGSEQAEK ddPTM_PC-9_Lapatinib_30min_R1 2 SQDATFSPGSEQAEK 15 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 SQDAT(0.471)FS(0.057)PGS(0.471)EQAEK;SQDAT(0.904)FS(0.004)PGS(0.091)EQAEK 213.02 3.4712e-17 18673000.0 54890.0 55907.0 60987.0 53146.0 62643.0 57454.0 58286.0 55011.0 57087.0 53271.0 True False 54107.25853440681 55777.550776415854 55972.884276627985 57054.53412985877 58958.46190087657 54996.82635181544 61303.76388441172 57567.01188752895 50657.26090723968 62478.82137085431 0.8660095908859006 0.8927433256997301 0.8958697211074267 0.9131819851594397 0.9436551555753268 0.8802475005949914 0.9811927072140522 0.9213844087395562 0.8107909175583574 1.0 15.93107961762502 -5.080505357035218 1.056391464950244 0.9202637668876068 0.8569953100041673 0.11583933623421816 0.0493978753762653 2.8447224302697083 3.6256892125525946 0.01619039104152945 0.1809636792029614 8.307964707397888e-06 5.080505357035218 -0.06326845688343952 SQDATFS(ph)PGSEQAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQDATFSPGSEQAEK 15 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 SQDAT(0.214)FS(0.654)PGS(0.132)EQAEK 108.25 0.00075377 23050000.0 44722.0 59364.0 56110.0 69818.0 58127.0 49420.0 68869.0 52969.0 39242.0 43827.0 True False 52292.55130023703 65257.265596991725 57447.87519835996 65906.32381301007 46737.43161816089 46828.32820106215 62345.22975161816 51578.619875294644 39815.84001142979 51772.488165658906 1.0100451640051382 1.2604622244189796 1.1096216781109929 1.272998964278604 0.9027464832019063 0.9045021759669597 1.2042154426136358 0.9962553800824884 0.7690540173388836 1.0 15.659898034777394 -6.268237451520871 24.991367665306903 0.9717646731515124 1.166390572470726 0.38434225153362656 0.1239722515475186 605.7084109898198 2226728.085457993 0.038660544156895384 0.04482379293734624 5.392157244494335e-07 6.268237451520871 0.1946258993192136 SQDATFSPGS(ph)EQAEK ddPTM_PC-9_AZD4547_30min_R2 3 SQDATFSPGSEQAEK 15 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 SQDAT(0.037)FS(0.049)PGS(0.914)EQAEK;SQDAT(0.023)FS(0.073)PGS(0.904)EQAEK;SQDATFS(0.059)PGS(0.941)EQAEK 180.56 2.0901999999999997e-05 69047100.0 133982.0 135259.0 152112.0 176699.0 178190.0 169137.0 155311.0 193347.0 151317.0 174176.0 True False 176585.48900127597 178978.82661609232 150094.8954917849 135963.7755223361 153451.3942832903 158560.83665231912 169133.37812272602 163469.66382205984 159315.30770022198 168078.15125504835 1.0506153695926739 1.0648548028381326 0.8930065827772288 0.8089318838117119 0.9129764525457993 0.9433756586941079 1.0062781917804202 0.972581281989499 0.947864469656563 1.0 17.35877267298686 -9.984796558620582 15.40402144059498 0.9999999836887322 0.953042909867509 0.032312621046438283 0.07164912345866066 0.0 0.0 0.07761370767655972 0.01882408910272165 1.0356271833936772e-10 9.984796558620582 -0.04695707382122327 SQDATFSPGS(ph)EQAEK ddPTM_PC-9_Lapatinib_30min_R1 1 SQDATFSPGSEQAEK 15 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 SQDAT(0.005)FS(0.06)PGS(0.935)EQAEK 175.27 6.2535e-05 34745000.0 85844.0 91037.0 85154.0 95487.0 93917.0 88129.0 80573.0 83247.0 93959.0 79049.0 True False 84619.8488181385 90826.20941979675 78152.9668239459 102509.43251529436 88392.98670792615 84359.92810873296 84744.67569328326 87114.95952811468 83376.34798786661 92712.51432382854 0.9127122636602889 0.9796542579198828 0.842960277735229 1.1056698576553206 0.9534094437260644 0.9099087509813243 0.9140586501330876 0.9396246036844327 0.8992998258751528 1.0 16.500476466344004 -6.54495206180245 19.534436676969523 0.9280928700966263 0.9627925584490901 0.035767681215683966 0.06650287820456331 64.88880410830357 57420.284327122805 0.021562359996089495 0.02157018328633477 2.8513329853416593e-07 6.54495206180245 0.03469968835246373 SQDATFSPGSEQAEKS(ph)PGPIVSR ddPTM_PC-9_AZD4547_30min_R2 2 SQDATFSPGSEQAEKSPGPIVSR 23 1 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 SQDATFS(0.002)PGSEQAEKS(0.838)PGPIVS(0.159)R;SQDATFSPGSEQAEKS(0.988)PGPIVS(0.012)R 97.366 3.7913e-06 170558000.0 338286.0 311991.0 387230.0 510330.0 449270.0 486720.0 347844.0 370400.0 313753.0 382777.0 True False 445853.91121408396 412835.98943346663 382095.07718841266 392681.3030199032 386896.6154646943 456285.3214578538 378801.4421368822 313163.1909452485 330337.34304055566 369376.09373825183 1.2070459317002415 1.1176575756578644 1.034433694182639 1.0630934423659966 1.0474327440878128 1.235286552629981 1.0255169421042971 0.8478166190342653 0.8943116477771842 1.0 18.494730971614402 -7.557309705224131 5.780376666609479 0.9068182124455825 1.1099978329298896 0.6257635999592538 0.07032015842711829 0.11948517291349711 10.922038234525218 0.03403260749530746 0.019680599653188198 2.771343092328484e-08 7.557309705224131 0.20317962048430716 SQDATFSPGSEQAEKS(ph)PGPIVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SQDATFSPGSEQAEKSPGPIVSR 23 1 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 SQDATFS(0.004)PGSEQAEKS(0.928)PGPIVS(0.068)R;SQDATFSPGSEQAEKS(0.973)PGPIVS(0.027)R;SQDATFS(0.001)PGS(0.003)EQAEKS(0.982)PGPIVS(0.013)R;SQDATFS(0.001)PGS(0.014)EQAEKS(0.981)PGPIVS(0.004)R 114.73 1.6233999999999998e-08 194835000.0 415171.0 395908.0 386656.0 537390.0 616550.0 548773.0 593970.0 513803.0 501145.0 487479.0 True False 485451.2502989734 435211.1297751795 395875.34544104635 507281.78054188803 495741.453441208 519994.3778203454 537704.8616295948 500316.2156692784 508473.2975518059 575855.0838183596 0.8430094027824854 0.7557650214519195 0.6874565434346607 0.8809191666386303 0.8608788345742526 0.9029952021477087 0.9337503075673141 0.868823128818798 0.8829882931313883 1.0 19.135346271935973 -5.879792842216465 6.891423206313434 0.8997789403380574 0.7620346531582561 0.6194643032656799 0.05117828738448734 0.14436909286948812 8.116330833109139 0.014304013163834362 0.021371615562409123 1.3188856949371526e-06 5.879792842216465 -0.13774428717980125 SQDATFSPGSEQAEKS(ph)PGPIVSR ddPTM_PC-9_Lapatinib_30min_R1 2 SQDATFSPGSEQAEKSPGPIVSR 23 1 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 SQDATFSPGSEQAEKS(0.974)PGPIVS(0.026)R;S(0.001)QDAT(0.051)FS(0.349)PGS(0.034)EQAEKS(0.562)PGPIVS(0.003)R 75.416 0.00018362 131598000.0 285794.0 207272.0 260240.0 232779.0 240851.0 263860.0 261820.0 300475.0 249497.0 162999.0 True False 281718.52515179943 206792.07441875344 238844.07175545066 249898.3441879808 226684.61771128475 252575.3228877017 275375.75850490096 314436.16543791693 221396.02054011548 191173.1599674852 1.4736301120916462 1.081700351942316 1.2493598567710726 1.3071832062120206 1.1857554572505855 1.3211861065154742 1.4404519889284508 1.6447715018750348 1.1580915468351864 1.0 17.54452046271419 -6.990906039212235 19.871236966552107 1.36688250071613 1.25190326646332 0.0 0.18611848318937854 45.523093882235834 99464.59947694336 0.06301946460876202 0.05538562318674611 1.0211603906269871e-07 6.990906039212235 -0.11497923425280998 SQDFGNLFSFPS(ph)YSQK ddPTM_PC-9_AZD4547_30min_R2 1 SQDFGNLFSFPSYSQK 16 0 Q02880;Q02880-2 Q02880 TOP2B DNA topoisomerase 2-beta 1 SQDFGNLFSFPS(0.988)YS(0.011)QK 135.08 7.9159e-06 0.0 8514.8 7983.9 9230.6 12841.0 10578.0 8664.9 11507.0 15945.0 11439.0 12937.0 True False 11222.32928115764 10564.53954132606 9108.196212833103 9880.705841472323 9109.427289570933 8123.082433226806 12531.10070798724 13481.066629648963 12043.642186818652 12484.079567716333 0.8989312524231611 0.8462409650644827 0.7295849216138273 0.7914645038809028 0.7296835333481687 0.6506753172442917 1.0037664883514923 1.0798606782762603 0.9647200757966453 1.0 13.60780183701565 -7.335120404219402 8.098398040410233 1.0200603320247623 0.7745733169706147 0.7401721323649191 0.0689331949357973 0.177715102699264 17.907129028218545 0.030677407220316137 0.020635091275506147 4.622528482089153e-08 7.335120404219402 -0.2454870150541476 SQDFHLFPALMMLS(ph)MTMLFLPVTGTLK ddPTM_PC-9_AZD4547_30min_R2 1 SQDFHLFPALMMLSMTMLFLPVTGTLK 27 0 C9JYT6;O95025 C9JYT6 SEMA3D Semaphorin-3D 1 S(0.164)QDFHLFPALMMLS(0.671)MT(0.163)MLFLPVTGTLK 42.321999999999996 0.038008 0.0 2086.6 833.98 3486.7 4418.7 1871.6 3737.5 878.74 4366.3 1873.6 1806.9 True False 2750.0953960238066 1103.547725632222 3440.4640798306923 3400.036983234467 1611.7606461676085 3503.793534164872 956.9461576550545 3691.5886625924268 1972.6346709697898 1743.6409809775569 1.5772142465256753 0.632898479487175 1.9731493566421148 1.949963909042942 0.9243649717753187 2.009469594021873 0.5488206391653809 2.117172458588792 1.1313307570138948 1.0 10.767887301678552 SQDQDS(ph)EVNELSR ddPTM_PC-9_AZD4547_30min_R2 1 SQDQDSEVNELSR 13 0 E7ERS3;Q86VM9 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 SQDQDS(1)EVNELSR 151.73 0.00013538 9545000.0 16654.0 21845.0 21183.0 20847.0 26013.0 25588.0 20483.0 25486.0 19371.0 23089.0 True False 21949.6255752806 28905.96904774203 20902.09957927368 16041.0462329393 22401.543967064543 23987.978314972777 22305.94731917116 21547.724310017773 20394.911513319723 22280.66113774463 0.9851424712930426 1.297356881334808 0.938127439309438 0.7199537811633834 1.0054254597102206 1.076627761028862 1.0011348936761886 0.9671043501269707 0.9153638389468458 1.0 14.443504422191216 -5.295925043724208 24.635235684897484 0.9514806429376451 1.1412497398399375 0.3078915867062647 0.11289905736008825 541.7156279979312 386979.86637974053 0.030306274008876616 0.06309276411335077 5.059119714361104e-06 5.295925043724208 0.18976909690229238 SQDQDS(ph)EVNELSR ddPTM_PC-9_Lapatinib_30min_R1 1 SQDQDSEVNELSR 13 0 E7ERS3;Q86VM9 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 SQDQDS(1)EVNELSR 200.81 3.2946999999999995e-07 12025000.0 21972.0 34816.0 26561.0 22276.0 27225.0 35710.0 33018.0 26940.0 32635.0 35262.0 True False 21658.675250828677 34735.38569108865 24377.257108424983 23914.2513505576 25623.679026409416 34182.76654407579 34727.510481685225 28191.73074930524 28959.30263821478 41356.98971633846 0.5237004772199901 0.8398915377868066 0.5894349969769324 0.5782396522228032 0.6195731169545579 0.8265293673096226 0.8397011175106346 0.6816678617730206 0.7002275271203827 1.0 15.335843558447893 -6.757422465780261 24.982424811437394 0.7916091699942901 0.6366713996550336 0.3817954740245708 0.11286959654998992 128.3775111375133 798419.6244403787 0.03763517919089923 0.03632743948545047 1.7481453294406194e-07 6.757422465780261 -0.1549377703392565 SQDS(ph)PGESEETLR ddPTM_PC-9_Lapatinib_30min_R1 1 SQDSPGESEETLR 13 0 Q8IWU2 Q8IWU2 LMTK2 Serine/threonine-protein kinase LMTK2 1 S(0.016)QDS(0.875)PGES(0.107)EET(0.002)LR 132.51 0.00039829 0.0 23085.0 21417.0 17627.0 12513.0 12367.0 14976.0 8214.9 8391.6 15726.0 6793.3 True False 22755.803666729487 21367.41025235655 16177.776102187705 13433.24776214433 11639.597374457484 14335.511390761107 8640.22732618559 8781.504371041932 13954.772277878525 7967.51285349674 2.856073668804003 2.681816853672088 2.030467524766865 1.6860026471433702 1.4608821583951583 1.7992454677333358 1.0844321791578426 1.10216381605057 1.7514590229690221 1.0 12.95991372607796 -5.047172682460085 0.6176252759884447 1.2713237745051098 3.727403231805993 0.8401195225624228 0.24273935489542683 1.0016876950941294 0.36216931530457974 0.12503146776640572 1.667965697269976 8.970720333324583e-06 5.047172682460085 2.4560794573008833 SQDSYPGS(ph)PSLS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 SQDSYPGSPSLSPR 14 0 A0A0D9SEU5;R4GMX8;Q6VN20-2;Q6VN20-3;Q6VN20 A0A0D9SEU5 RANBP10 Ran-binding protein 10 2 S(0.002)QDS(0.004)YPGS(0.992)PS(0.005)LS(0.997)PR 134.08 0.00030468 0.0 20216.0 18664.0 22603.0 20303.0 23707.0 22072.0 16015.0 18046.0 22138.0 15770.0 True False 19927.716132839654 18620.784654712734 20744.668590103178 21796.150348822546 22312.6008697553 21128.032012345033 16844.178338003167 18884.483040161926 19644.585316525165 18495.823487795846 1.0774170799147504 1.0067561829295864 1.1215866438058946 1.1784363298668137 1.206358877963876 1.14231367023404 0.9107017240469185 1.021013368375976 1.0621092556104523 1.0 14.174911914415866 -7.238584105202206 24.75130689407021 1.000207192115616 1.1232611176539529 0.48953591630560134 0.06185989256356615 681.2261503676477 737740.4623913124 0.026591558052153682 0.02058365637505041 5.7731905863365843e-08 7.238584105202206 0.12305392553833694 SQDSYPGS(ph)PSLSPR ddPTM_PC-9_AZD4547_30min_R2 2 SQDSYPGSPSLSPR 14 0 A0A0D9SEU5;R4GMX8;Q6VN20-2;Q6VN20-3;Q6VN20 A0A0D9SEU5 RANBP10 Ran-binding protein 10 1 SQDSYPGS(0.641)PS(0.355)LS(0.004)PR;SQDSYPGS(0.933)PS(0.067)LSPR 181.81 2.6345e-05 14715300.0 36971.0 45648.0 71981.0 109961.0 88320.0 83483.0 74748.0 110230.0 69075.0 86378.0 True False 48727.00895542805 60402.823304707184 71026.48490845019 84611.19033051464 76058.2925141715 78262.79481275863 81400.42719393682 93196.48633340899 72726.16348059266 83353.9325114169 0.5845796051524499 0.7246547521490228 0.8521071864092526 1.0150833653700206 0.9124739556079596 0.9389214456323227 0.9765637294051781 1.1180814572922995 0.8724982887955698 1.0 16.34696264451862 -5.093467157619715 1.2282688179813341 0.9814773186404049 0.5137008415626203 0.8044785239424724 0.06432433087969693 0.3706391596884133 0.6984609709457507 0.01992464595253942 0.19189458859814235 8.063671784504505e-06 5.093467157619715 -0.4677764770777846 SQDSYPGS(ph)PSLSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQDSYPGSPSLSPR 14 0 A0A0D9SEU5;R4GMX8;Q6VN20-2;Q6VN20-3;Q6VN20 A0A0D9SEU5 RANBP10 Ran-binding protein 10 1 SQDS(0.005)YPGS(0.749)PS(0.235)LS(0.012)PR;SQDSYPGS(0.935)PS(0.065)LSPR 214.63 2.6013000000000003e-15 5845700.0 26763.0 24689.0 32963.0 39421.4 47860.0 38893.0 43012.0 39957.0 38430.0 31654.2 True False 31293.4473066554 27139.96075608329 33748.96293287364 37212.746763903226 38482.17656588469 36853.38261278654 38937.591980086814 38908.171087941 38991.966047582835 37392.85588549067 0.8368830506684569 0.7258060427156152 0.9025510925462382 0.9951833280095267 1.0291317861286091 0.9855728250777053 1.0413109953229205 1.0405241901578934 1.0427651251615861 1.0 15.190475041023449 -5.578779607667432 2.5428235780703363 1.0227308083627646 0.781246441205347 0.8961652532058095 0.032467643932353095 0.07409041341669392 0.9603821078720765 0.008879784896158543 0.01911174597813641 2.6376695899708525e-06 5.578779607667432 -0.2414843671574176 SQDSYPGS(ph)PSLSPR ddPTM_PC-9_Lapatinib_30min_R1 2 SQDSYPGSPSLSPR 14 0 A0A0D9SEU5;R4GMX8;Q6VN20-2;Q6VN20-3;Q6VN20 A0A0D9SEU5 RANBP10 Ran-binding protein 10 1 SQDS(0.025)Y(0.049)PGS(0.925)PSLSPR;SQDSYPGS(0.602)PS(0.398)LSPR 193.3 1.6617e-07 15744600.0 62196.0 59690.0 59952.0 50666.0 63642.0 59487.0 48111.0 56017.0 55654.0 51153.0 True False 61309.07363465048 59551.79147234264 55022.97798141242 54392.14665682133 59898.70268498615 56942.879680969905 50601.95217106903 58619.75432011249 49385.66045739871 59994.72789291195 1.0219076873568722 0.992617077597886 0.9171302198357514 0.9066154405085228 0.9983994392291069 0.949131393388608 0.8434399812828783 0.9770817599964162 0.8231666713373553 1.0 15.87254810732167 -5.134787099964709 3.5781898792710316 0.9256855546144983 1.0168090069769857 0.25068286871545653 0.0564128615730774 0.31930952865461204 7.227508405652851 0.014114085547235393 0.046284907650589464 7.331838667786748e-06 5.134787099964709 0.09112345236248742 SQDSYPGSPS(ph)LSPR ddPTM_PC-9_AZD4547_30min_R2 1 SQDSYPGSPSLSPR 14 0 A0A0D9SEU5;R4GMX8;Q6VN20-2;Q6VN20-3;Q6VN20 A0A0D9SEU5 RANBP10 Ran-binding protein 10 1 SQDSYPGS(0.038)PS(0.508)LS(0.454)PR 122.96 5.0226e-05 16197000.0 18630.0 15249.0 16221.0 26790.0 25458.0 23019.0 17739.0 24310.0 23187.0 19852.0 True False 24553.952471927318 20177.941039552214 16005.898941386875 20613.979401374 21923.596137067187 21579.618291087954 19317.73663500353 20553.448088226178 24412.617482801295 19156.98752247852 1.2817230497809784 1.0532940534557285 0.8355123122884427 1.0760553754699618 1.1444177280661882 1.1264619902146282 1.008391147738463 1.0728956243307604 1.2743453246057552 1.0 14.225583091558885 -5.995980197958095 24.993249102389704 1.1048980744715056 1.0397042072090985 0.024213389951135422 0.12350411322835972 417.36896572035 2594953.8068975993 0.03575462812679141 0.052793593914383444 1.0092989049058565e-06 5.995980197958095 -0.06519386726240706 SQDSYPGSPS(ph)LSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQDSYPGSPSLSPR 14 0 A0A0D9SEU5;R4GMX8;Q6VN20-2;Q6VN20-3;Q6VN20 A0A0D9SEU5 RANBP10 Ran-binding protein 10 1 SQDS(0.004)YPGS(0.117)PS(0.865)LS(0.013)PR 93.10600000000001 0.0038841 6976000.0 13680.0 11899.0 19394.0 21757.0 34205.0 26688.0 24463.0 24739.0 19454.0 21537.0 True False 15995.753807683977 13080.254082248573 19856.426512154587 20538.025827145724 27502.775792647 25288.434298461078 22145.68754321733 24089.627463137196 19738.47794664785 25441.487613201814 0.6287271424876758 0.5141308669175899 0.7804742715536379 0.8072651308521896 1.0810207410346384 0.9939841051330145 0.8704556856072259 0.9468639503075628 0.775838199665863 1.0 14.63489540981961 -5.596792369805465 1.9377335600201977 0.9374427103541759 0.570014917222491 0.7172559558598977 0.08886655993740972 0.17831406652602008 1.332639845371075 0.02676762470536413 0.06457480759744158 2.530507507992988e-06 5.596792369805465 -0.36742779313168494 SQDSYPGSPSLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 SQDSYPGSPSLSPR 14 0 A0A0D9SEU5;R4GMX8;Q6VN20-2;Q6VN20-3;Q6VN20 A0A0D9SEU5 RANBP10 Ran-binding protein 10 1 SQDSYPGS(0.002)PS(0.005)LS(0.993)PR 132.25 1.3826e-05 14875000.0 19222.0 20147.0 25703.0 35284.0 31173.0 25005.0 23936.0 31314.0 24218.0 25696.0 True False 25334.196157562383 26659.123753941807 25362.16142595816 27149.818932365833 26845.167035147908 23441.433397135148 26066.25762982382 26475.1408241347 25498.11403797308 24796.390861253676 1.0216888538061024 1.0751211296478955 1.0228166497241558 1.0949101054375447 1.0826239667441122 0.9453566661495179 1.051211758020576 1.0677013833293056 1.0282994077906678 1.0 14.59784252977908 SQDSYPGSPSLS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 SQDSYPGSPSLSPR 14 0 A0A0D9SEU5;R4GMX8;Q6VN20-2;Q6VN20-3;Q6VN20 A0A0D9SEU5 RANBP10 Ran-binding protein 10 1 SQDS(0.087)YPGS(0.036)PS(0.203)LS(0.674)PR;SQDS(0.006)YPGS(0.152)PS(0.287)LS(0.555)PR 104.16 0.001093 13523000.0 21784.3 27006.0 26828.0 21097.6 31281.0 23046.0 23840.0 23990.0 28327.0 22074.0 True False 21473.65188724864 26943.469266243683 24622.3053990748 22649.18788353044 29441.113080812207 22060.37630284993 25074.31854998412 25104.662979800753 25136.51496346591 25889.461488243862 0.8294360196329154 1.040711846342514 0.9510551391830045 0.8748419851766791 1.1371852247363705 0.8520986932411599 0.9685144884674449 0.9696865649832277 0.9709168719048151 1.0 14.660077336432124 -4.742173848523982 24.7808987440597 0.970262948748169 0.8294354915234939 0.24615665808307785 0.07559834798012982 1761.9302000365012 2266206.5620142515 0.01780329256099138 0.6485373392458141 1.8106151564394216e-05 4.742173848523982 -0.14082745722467505 SQDSYPVS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQDSYPVSPR 10 0 Q96S59-2;Q96S59-3;Q96S59 Q96S59-2 RANBP9 Ran-binding protein 9 1 SQDSYPVS(1)PR 69.229 0.038926999999999996 4986000.0 27912.0 59964.0 50072.0 43647.0 42227.0 51080.0 46098.0 49147.0 42511.0 41023.0 True False 32636.95031287097 65916.82963172981 51265.90637911749 41201.600095483234 33952.92247905584 48401.27487879921 41731.263719381604 47856.94332555089 43132.64295208939 48460.14516211066 0.6734802424485655 1.3602276553489967 1.0578983246463851 0.8502161922473431 0.7006360044006321 0.9987851814493226 0.8611460733305821 0.9875526201058227 0.8900642539926465 1.0 15.56451110593061 -5.751065265420847 23.90235719110981 0.8922217053560649 1.0635047689354926 0.0961930157344173 0.17654881936094208 221.25944403121972 509781.10754881584 0.04619608527253588 0.07879379835826875 1.7739228771737084e-06 5.751065265420847 0.17128306357942769 SQDSYPVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 SQDSYPVSPR 10 0 Q96S59-2;Q96S59-3;Q96S59 Q96S59-2 RANBP9 Ran-binding protein 9 1 SQDSYPVS(1)PR 71.268 0.033612 7076500.0 23308.0 35400.0 32905.0 37085.0 31081.0 32043.0 36410.0 34634.0 35297.0 30967.0 True False 22975.623645836295 35318.03347496952 30199.677916973167 39812.3546119334 29252.876687597083 30672.59558588128 38295.13164450176 36243.22207763316 31321.480166112087 36319.604689066226 0.6325956420101938 0.9724233999056101 0.8314979795488958 1.096167068798484 0.8054293800285626 0.8445189821990288 1.0543928540067578 0.9978969316409971 0.8623849415283203 1.0 15.148460879638975 -4.757530353774305 24.946410427195012 0.9382511919989414 0.6325951885569233 0.485063347923544 0.0951545558706634 97.02245860428984 619083.7022047165 0.023240055144229388 0.17108729545439488 1.7477111068656655e-05 4.757530353774305 -0.30565600344201804 SQDVAVS(ph)PQQQQCSK ddPTM_PC-9_AZD4547_30min_R2 3 SQDVAVSPQQQQCSK 15 0 H3BQ37;H3BPW9;Q96F86;H3BTD6 H3BQ37 EDC3 Enhancer of mRNA-decapping protein 3 1 S(0.002)QDVAVS(0.983)PQQQQCS(0.015)K;SQDVAVS(1)PQQQQCSK;SQDVAVS(1)PQQQQCSK 145.79 1.6227e-05 263179000.0 342108.0 294034.0 438980.0 550730.0 524580.0 447940.0 402590.0 486420.0 401210.0 464670.0 True False 450891.227711547 389074.740351741 433158.8383755636 423767.7071936813 451751.1219099195 419930.24098831 438419.73007982905 411254.96581962024 422417.1415135512 448402.0447345415 1.00555123021011 0.8676917175569018 0.9660054931997422 0.9450619420001887 1.007468915930927 0.9365038494347476 0.9777380260149748 0.9171567584244342 0.9420499894545002 1.0 18.774433331352803 SQDVAVS(ph)PQQQQCSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SQDVAVSPQQQQCSK 15 0 H3BQ37;H3BPW9;Q96F86;H3BTD6 H3BQ37 EDC3 Enhancer of mRNA-decapping protein 3 1 SQDVAVS(1)PQQQQCSK;S(0.04)QDVAVS(0.96)PQQQQCSK;SQDVAVS(1)PQQQQCSK;SQDVAVS(1)PQQQQCSK;S(0.001)QDVAVS(0.999)PQQQQCSK;SQDVAVS(1)PQQQQCSK 221.13 2.4711e-18 294261900.0 387100.0 421154.0 441814.0 543597.0 588465.0 617739.0 632751.0 600507.0 608660.0 473517.0 True False 452628.3844264951 462963.38581017806 452348.52134892606 513141.0224552522 473159.5075813487 585343.6793726421 572812.244559469 584744.3275397611 617560.5010284086 559361.8837414917 0.8091870354106514 0.8276634487739531 0.8086867097972987 0.9173685897632589 0.8458915799132618 1.0464489919430366 1.0240459016048964 1.0453774998548164 1.1040446604935514 1.0 19.093422422904716 -6.759770948413561 9.254233081029634 1.0457189924055852 0.8431908577271865 0.8790936488548055 0.03749387013619062 0.03521766047600282 39.823654704785376 0.013202759506446086 0.012452298861862056 1.7387176053575767e-07 6.759770948413561 -0.2025281346783987 SQDVAVS(ph)PQQQQCSK ddPTM_PC-9_Lapatinib_30min_R1 4 SQDVAVSPQQQQCSK 15 0 H3BQ37;H3BPW9;Q96F86;H3BTD6 H3BQ37 EDC3 Enhancer of mRNA-decapping protein 3 1 S(0.019)QDVAVS(0.981)PQQQQCSK;S(0.033)QDVAVS(0.967)PQQQQCSK;SQDVAVS(1)PQQQQCSK;SQDVAVS(0.996)PQQQQCS(0.004)K 258.13 3.9596999999999996e-50 342344000.0 433653.0 395113.0 493541.0 440974.0 508315.0 508619.0 440115.0 484152.0 557830.0 434238.0 True False 427469.0286977788 394198.14012417034 452963.9641033547 473404.6990061396 478416.911085741 486866.5510187977 462902.0012007665 506647.46940377355 495001.3111896851 509295.4597142359 0.839334065411913 0.7740067825174677 0.8893932892264765 0.9295286065808744 0.9393700689069155 0.955960909786977 0.9089065931600869 0.9948006795270703 0.9719334852649751 1.0 18.958143330339148 -5.5854529339864785 1.9011245471275084 0.9575318036797699 0.8043500134262055 0.7961927724580148 0.03039544079155246 0.1467199465794574 1.0512467084257529 0.00896652411481437 0.022198959782010756 2.597449220815325e-06 5.5854529339864785 -0.15318179025356438 SQEDEIS(ph)SPVNK ddPTM_PC-9_AZD4547_30min_R2 1 SQEDEISSPVNK 12 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 SQEDEIS(0.5)S(0.5)PVNK 203.85 9.905300000000001e-08 44854000.0 202120.0 202150.0 267180.0 290620.0 273380.0 242080.0 244300.0 247880.0 245200.0 262160.0 True False 266389.9556428309 267491.0342412933 263637.0186276889 223622.04903424115 235425.90588229377 226942.6993312728 266042.22672818985 209575.84171573393 258160.77141427883 252981.8581952934 1.0530002330727877 1.0573526344912818 1.0421182787904504 0.8839450015487377 0.930603907970954 0.897071042762603 1.0516257119228458 0.8284224142031106 1.0204714806663626 1.0 17.948674404691886 -5.674052814051079 7.448653095588247 0.9394918426297355 1.0531826524159726 0.3697538696544914 0.0633781155421916 0.22232453372830063 16.203658793697468 0.016117780780126826 0.027987834999788724 2.1181035394572008e-06 5.674052814051079 0.11369080978623713 SQEDEIS(ph)SPVNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQEDEISSPVNK 12 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 SQEDEIS(0.5)S(0.5)PVNK 209.11 4.1645e-08 33658000.0 236730.0 243960.0 225710.0 267690.0 306540.0 289430.0 324720.0 269260.0 275850.0 208750.0 True False 276803.71336937376 268178.736524528 231091.7824099418 252692.1971626891 246475.6875158021 274251.7812876047 293960.1708307862 262192.2103045522 279883.7843930718 246594.72253590936 1.1225046121133648 1.0875282883861213 0.9371319062851802 1.0247267036539753 0.9995172848028411 1.1121559231571467 1.1920781102198141 1.063251506797237 1.134995029556299 1.0 17.9117823988623 -6.77548695089626 24.594155835556446 1.1101732367932735 1.0313118516865099 0.19523618306300505 0.06562681135058697 285.5801259798477 499983.25320009026 0.023405545675296957 0.020744979723680723 1.676922720938178e-07 6.77548695089626 -0.07886138510676366 SQEDEIS(ph)SPVNK ddPTM_PC-9_Lapatinib_30min_R1 1 SQEDEISSPVNK 12 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 SQEDEIS(0.673)S(0.327)PVNK 115.57 0.00071648 6239600.0 64830.0 65435.0 60325.0 60476.0 61480.0 65169.0 54990.0 53172.0 65795.0 45361.0 True False 63905.51231163406 65283.48927781443 55365.31136123405 64923.60678202199 57863.86727433058 62381.87378635887 57837.113131863545 55642.56523392939 58384.47424793449 53201.588410266806 1.2011955699296681 1.2270966192659027 1.0406702697348356 1.220332112668521 1.0876342042292115 1.1725566031092496 1.0871313218291463 1.0458816530972508 1.0974197574271578 1.0 15.699181699663228 -1.5228787452895216 0.07949758573192549 0.8842825258195361 1.7357019528926554 0.49766873608879547 0.054751046925855994 161.92375676508723 0.9427189865542643 1.5361552000390661 15.158765112654475 0.02999999999936559 1.5228787452895216 0.8514194270731192 SQEDEISS(ph)PVNK ddPTM_PC-9_AZD4547_30min_R2 2 SQEDEISSPVNK 12 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 SQEDEIS(0.03)S(0.97)PVNK;SQEDEIS(0.023)S(0.977)PVNK 170.0 0.00021137 49531200.0 270388.0 255976.0 355798.0 392077.0 378163.0 310517.0 327149.0 390637.0 348783.0 360190.0 True False 356365.7595802185 338715.23611649376 351079.8860457167 301689.7051792651 325661.59501853015 291100.3229025487 356264.6272284104 330273.0275952448 367218.9573253928 347579.8577333027 1.0252773618822792 0.9744961584522808 1.0100697098365796 0.8679723478417182 0.936940354203176 0.8375063066108663 1.0249864003965716 0.9502076148746876 1.0565024098926905 1.0 18.40698495477598 SQEDEISS(ph)PVNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SQEDEISSPVNK 12 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 SQEDEIS(0.023)S(0.977)PVNK;SQEDEIS(0.076)S(0.924)PVNK;SQEDEIS(0.158)S(0.842)PVNK 225.33 2.2893e-15 40598900.0 217682.0 230378.0 228926.0 244301.0 301420.0 241857.0 277724.0 263605.0 218020.0 184840.0 True False 254531.26318452202 253248.40532483917 234384.46404668957 230613.60700452878 242358.91476157503 229173.59315508502 251415.97217236206 256685.64806258446 221208.13004668267 218350.02880736534 1.1657029063599382 1.1598276707728863 1.0734345460218384 1.056164765647834 1.1099559550568734 1.049569786671604 1.1514354889056069 1.1755695635334213 1.013089539098888 1.0 17.736283195892696 -14.522878743109503 0.1785525774044842 0.5647008462696094 1.1295047865947982 0.31669236218463137 0.051537116665543656 186.055220660632 1.7809799958575343 28.69062658998221 0.17254387732054396 3.0000000149955925e-15 14.522878743109503 0.5648039403251889 SQEDEISS(ph)PVNK ddPTM_PC-9_Lapatinib_30min_R1 2 SQEDEISSPVNK 12 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 SQEDEIS(0.076)S(0.924)PVNK;SQEDEIS(0.076)S(0.924)PVNK 219.97 3.4303e-11 87125000.0 763950.0 816360.0 792200.0 720590.0 655420.0 766980.0 683200.0 701330.0 746310.0 512940.0 True False 753055.9329087265 814469.7685770092 727068.373980433 773584.5924177729 616869.4842052986 734178.053317705 718572.7530767256 733916.3521310391 662252.7088072958 601600.9955504125 1.251753136179148 1.3538371355782755 1.2085558025302614 1.2858765163944093 1.0253797596211036 1.2203737339995526 1.1944341156205938 1.2199387260979675 1.1008171756786942 1.0 19.198447428876655 -1.5229030741001015 0.02490151037016861 1.2363890723038962e-06 2.814828753275089 0.5199243760356624 0.07366412752049958 1660.3281971752215 3.1911788510296204 124.31362706588727 259.09298158726205 0.02999831947173979 1.5229030741001015 2.8148275168860164 SQEEPKDT(ph)FEHDPSESIDEFNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQEEPKDTFEHDPSESIDEFNK 22 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 S(0.441)QEEPKDT(0.541)FEHDPS(0.016)ES(0.001)IDEFNK;S(0.015)QEEPKDT(0.981)FEHDPS(0.003)ESIDEFNK 99.881 7.3405e-05 17470700.0 41653.0 54468.0 43451.0 44252.0 53096.0 38613.0 54121.0 36407.0 39321.6 41803.0 True False 48704.030215750005 59875.22307352848 44487.03662883514 41772.70390691968 42692.21995282517 36588.06630569839 48994.26707789171 35451.3548264051 39896.604010841394 49381.5529876341 0.9862798407321504 1.212501824082409 0.900883709347403 0.8459171771568263 0.8645378156396977 0.7409257929749719 0.9921572756158686 0.7179068433769724 0.8079252594755801 1.0 15.59168458768522 -5.421280677386812 5.305940022685108 0.8446146198742237 1.097135720587556 0.48311505357927176 0.10020006692169837 0.16273221032408688 6.791121536600361 0.024905782515471014 0.05293734557765191 3.790699191317905e-06 5.421280677386812 0.25252110071333234 SQEEPKDTFEHDPS(ph)ESIDEFNK ddPTM_PC-9_Lapatinib_30min_R1 1 SQEEPKDTFEHDPSESIDEFNK 22 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SQEEPKDT(0.002)FEHDPS(0.499)ES(0.499)IDEFNK 83.06299999999999 0.00014218 4650600.0 32291.0 30845.0 32798.0 30407.0 26900.0 32181.0 28290.0 29312.0 28048.0 22253.0 True False 31830.524418555855 30773.580297611148 30101.47504394123 32643.232214778443 25317.79488743482 30804.693647574994 29754.717775966907 30673.942528716954 24888.938881466183 26099.401399741346 1.2195882936560878 1.1790914215341401 1.153339671776516 1.2507272375642282 0.9700527034955571 1.180283531249122 1.1400536479837344 1.1752737949392564 0.9536210620414015 1.0 14.671729097933573 -2.8618361873265217 0.06714752437662043 0.7998068680634661 1.7326719033901405 0.3772220556840997 0.08017669638840351 238.89925625980615 1.5503747567131776 4.812082605235626 22.514575717987956 0.001374560351262755 2.8618361873265217 0.9328650353266744 SQEEPKDTFEHDPSES(ph)IDEFNK ddPTM_PC-9_AZD4547_30min_R2 2 SQEEPKDTFEHDPSESIDEFNK 22 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SQEEPKDTFEHDPS(0.135)ES(0.865)IDEFNK;SQEEPKDTFEHDPS(0.134)ES(0.866)IDEFNK 62.403999999999996 0.002187 13726200.0 166412.0 168540.0 168908.0 182331.0 181316.0 190221.0 172739.0 194396.0 173873.0 189829.0 True False 219327.5544153717 223017.25902066575 166668.16955747333 140297.40493586895 156143.40314197826 178326.4507992982 188112.4363602159 164356.56497568174 183063.57181123525 183183.14448945108 1.1973129679952734 1.2174551301771577 0.9098444620655106 0.7658859952802493 0.8523895775299897 0.97348722392724 1.0269090908145684 0.8972253720928265 0.9993472506515318 1.0 17.4829272350757 -5.261294037106672 24.99938613635838 0.9211130009382343 1.2073840749997793 0.6895373558152197 0.07483208951480978 7.181817334660906 1235003.8859264771 0.021181065083180618 0.04929689487229444 5.479058821258294e-06 5.261294037106672 0.28627107406154495 SQEEPKDTFEHDPSES(ph)IDEFNK ddPTM_PC-9_Lapatinib_30min_R1 2 SQEEPKDTFEHDPSESIDEFNK 22 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SQEEPKDTFEHDPS(0.048)ES(0.951)IDEFNK;SQEEPKDTFEHDPS(0.055)ES(0.945)IDEFNK 62.831 0.0019829 16320200.0 202328.0 200724.0 192789.0 192241.0 185594.0 177441.0 174252.0 171138.0 172453.0 146564.0 True False 199442.76561758886 200259.23591044566 176938.63260706092 206379.04443717678 174677.72581184295 169852.26206517353 183273.91593841562 179089.69624998534 153029.5271294026 171897.39211574584 1.160243114586029 1.1649928683944348 1.0293270330007136 1.20059438887946 1.0161743797382625 0.9881026115323772 1.066182061767461 1.041840682081998 0.8902376309837283 1.0 17.391188132049642 -6.232350292791561 0.48378496757051936 0.9707163766220871 1.184109884168724 0.5157749535931129 0.06281216500186532 1.2074407228876123 0.5333390241642846 0.05334788665067302 0.12587001978976742 5.856655884134503e-07 6.232350292791561 0.213393507546637 SQELSLPQDLEDT(ph)QLSDKGCLAGGGSPK ddPTM_PC-9_Lapatinib_30min_R1 2 SQELSLPQDLEDTQLSDKGCLAGGGSPK 28 1 Q9H257-2;Q9H257 Q9H257-2 CARD9 Caspase recruitment domain-containing protein 9 1 SQELSLPQDLEDT(0.458)QLS(0.271)DKGCLAGGGS(0.271)PK;SQELS(0.001)LPQDLEDT(0.744)QLS(0.05)DKGCLAGGGS(0.205)PK 53.865 0.0032927 5832600.0 42588.7 34623.1 30928.7 35499.4 29445.5 30049.1 21796.9 25242.6 32621.8 25121.3 True False 41981.37732818895 34542.93233918693 28385.861674234555 38110.144298526895 27713.57358208037 28763.97004087335 22925.43682894919 26415.463348641886 28947.589361216942 29463.483232971852 1.424861310396886 1.1723981195994775 0.9634251812585636 1.2934704290454966 0.940607509402242 0.9762582995850371 0.7780966237995209 0.8965492348535694 0.982490397768802 1.0 14.846640378350768 -1.522878781732556 0.4141163007691001 0.9088977353241703 9.748904033412128 0.6165505268331712 0.11480049820328198 51.72737968506062 0.6699818647242513 0.08153076877453153 377.1560303817953 0.029999997481970065 1.522878781732556 8.840006298087957 SQELSLPQDLEDTQLSDKGCLAGGGS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQELSLPQDLEDTQLSDKGCLAGGGSPK 28 1 Q9H257-2;Q9H257 Q9H257-2 CARD9 Caspase recruitment domain-containing protein 9 1 SQELSLPQDLEDT(0.052)QLS(0.16)DKGCLAGGGS(0.788)PK 44.263999999999996 0.016635 3128400.0 19127.0 12904.0 12703.0 19931.0 19611.0 18445.0 22201.0 17494.0 17613.0 18829.0 True False 22364.823324530054 14185.02384043496 13005.887696395777 18814.330687173842 15768.365328741429 17477.711729433264 20097.960558679133 17034.801036425157 17870.556804477666 22242.548649718 1.0054973320161134 0.6377427364024133 0.5847301000086009 0.8458711716659493 0.708927990989978 0.7857782848844013 0.9035817286583273 0.7658655176928716 0.8034401581360253 1.0 14.44103448746887 -7.026452682885943 7.286633887799998 0.8484260237546781 0.7454492949162477 0.14611790288625448 0.12301863586989005 0.43530468767717734 92.15993813044065 0.045885733321972925 0.03668153414964259 9.409083379978149e-08 7.026452682885943 -0.10297672883843045 SQEPS(ph)PVGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQEPSPVGSR 10 0 M0QZ12;Q96CP6-2;Q96CP6-3;Q96CP6 M0QZ12 GRAMD1A GRAM domain-containing protein 1A 1 SQEPS(0.996)PVGS(0.004)R 69.352 0.038606 3621100.0 12446.0 25196.0 27260.0 19685.0 26840.0 21217.0 25625.0 18925.0 21798.0 18299.0 True False 14552.86198029494 27697.29236543702 27909.981784125706 18582.113269631085 21580.894672552142 20104.34316960616 23197.614491065848 18428.23880269498 22116.754512235526 21616.463845195693 0.6732304638036043 1.2813054236709862 1.2911446564063604 0.8596278004906432 0.9983545332438147 0.9300477318390998 1.0731456660623782 0.8525094083226151 1.0231439642775348 1.0 14.399842916948918 -5.786872364547381 24.99996485275795 0.9610227266015725 1.101835065319576 0.08912349119422502 0.17149600511466329 460.18792389728463 452350.9827562488 0.047453144570746536 0.07041355316511626 1.6335319584974864e-06 5.786872364547381 0.14081233871800358 SQESGYYDR ddPTM_PC-9_AZD4547_30min_R2 1 SQESGYYDR 9 0 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 0 121.73 0.007366800000000001 12136000.0 21472.0 23318.0 35043.0 45931.0 40853.0 32692.0 25241.0 31806.0 25796.0 33509.0 False True 28299.64935465503 30855.087491657087 34578.306923310556 35342.31757687607 35181.26612411054 30647.764071951304 27487.40010170382 26891.113529169972 27159.52389642224 32335.860109345802 0.8751784940607096 0.9542064873894992 1.0693486057393178 1.0929759547871538 1.0879953712424166 0.9477949239115306 0.8500593461486227 0.83161893446582 0.8399196373493871 1.0 14.980847365039136 -7.029947398304479 4.482832645431665 0.8684809279681978 1.020138225268455 0.4094322312654566 0.07597062231199662 0.20173040192262345 9.616148431659965 0.031122146490555756 0.024964356721787886 9.33367343291596e-08 7.029947398304479 0.15165729730025723 SQESGYYDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQESGYYDR 9 0 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 0 117.01 0.0086791 9019600.0 41034.0 52668.0 46517.0 55855.0 50557.0 54934.0 50195.0 41714.0 51888.0 37010.0 False True 47980.24574155733 57896.53096931405 47626.141696704864 52725.625434353264 40650.71877646119 52053.16433421991 45440.16621967028 40619.0516996364 52646.763837548235 43719.62002900123 1.0974534021505638 1.324268850710702 1.089353971171576 1.205994594632294 0.9298049422546606 1.190613374491605 1.0393540975316742 0.9290806203871836 1.204190791288333 1.0 15.415993242026381 -6.227105852241542 24.988841499618324 1.0519089472692167 1.1832025446421002 0.2668268928153338 0.10576232387420273 831.6081731175705 605266.1253375963 0.02967596476211468 0.038309687818384376 5.927808262516945e-07 6.227105852241542 0.13129359737288349 SQFCENS(ph)NDTVK ddPTM_PC-9_Lapatinib_30min_R1 1 SQFCENSNDTVK 12 0 Q14207 Q14207 NPAT Protein NPAT 1 SQFCENS(0.997)NDT(0.003)VK 139.0 7.1119e-05 4008800.0 14382.0 19305.0 19412.0 17403.0 14687.0 13120.0 18263.0 12280.0 14824.0 11936.0 True False 14176.91004266421 19260.30045859567 17816.02029248695 18682.87467470614 13823.13953575299 12558.888184213783 19208.56877845469 12850.573630344035 13154.36501635962 13999.121696279719 1.0126999643436017 1.375822060587852 1.2726527191503434 1.3345747740496559 0.987429057026235 0.8971197234145997 1.3721267087462627 0.9179557053039327 0.9396564514369073 1.0 13.77304869499323 -6.266828800411684 24.942024344537945 1.0265032478251788 1.259694525670637 0.34621265962175973 0.15427790573077377 502.08352736312 2323618.604718928 0.047520879539380285 0.05543580392500141 5.409675311964571e-07 6.266828800411684 0.23319127784545834 SQFFSQSVDSPSSEKSPVMT(ph)PFK ddPTM_PC-9_AZD4547_30min_R2 1 SQFFSQSVDSPSSEKSPVMTPFK 23 1 Q9UPQ0-5;Q9UPQ0-4 Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 S(0.001)QFFS(0.002)QS(0.009)VDS(0.023)PS(0.023)S(0.019)EKS(0.275)PVMT(0.649)PFK 50.776 0.020806 3372900.0 9686.9 11617.0 9999.5 13360.0 14278.0 9538.6 8856.4 9418.3 12023.0 12128.0 True False 12767.132699963104 15371.968067183307 9866.90009644277 10280.058409942403 12295.746156219866 8942.149834109716 9644.602442879823 7962.918146003309 12658.511234559026 11703.402411475905 1.0908906872623765 1.3134614641730296 0.8430796233040461 0.878382033575311 1.0506129520218097 0.7640641174007132 0.8240853474732013 0.6803934331263513 1.081609500340395 1.0 13.514640390432858 -5.269846678687414 24.98487926153823 0.87729352343105 1.2021760794995344 0.47993108095776893 0.12930732807962522 423.63294482103777 1258958.2572331785 0.03291730551262157 0.07038384567240594 5.372214210586823e-06 5.269846678687414 0.3248825560684844 SQGDEAGGHGEDRPEPLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 SQGDEAGGHGEDRPEPLSPK 20 1 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 S(0.001)QGDEAGGHGEDRPEPLS(0.999)PK 51.938 0.018690000000000002 27769000.0 32094.0 24296.0 23263.0 27768.0 32475.0 24062.0 26672.0 27581.0 26672.0 22529.0 True False 31636.33367468124 24239.74410474178 21350.40593777685 29810.15135133252 30564.88434830654 23032.924351261605 28052.945652901715 28862.51394939077 23667.91849138855 26423.107631994448 1.1972979906562675 0.9173691619600058 0.8080202463363805 1.1281849117261615 1.1567482816176027 0.8716962694945148 1.061682298827477 1.0923209469291404 0.8957280430834043 1.0 14.689512532039254 -4.74653310187548 24.6671598627495 0.9973094877818371 1.1972986186128336 0.23243287853795602 0.11137582395647772 1125.6484651866338 1862618.1103894622 0.028592021598949063 0.6315234362010205 1.7925319205816648e-05 4.74653310187548 0.19998913083099645 SQGS(ph)GNEAEPLGK ddPTM_PC-9_AZD4547_30min_R2 2 SQGSGNEAEPLGK 13 0 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;Q9NUQ6-2 B8ZZZ7 SPATS2L SPATS2-like protein 1 SQGS(1)GNEAEPLGK;S(0.002)QGS(0.998)GNEAEPLGK 147.83 0.00011096 71313000.0 105570.0 118227.0 185182.0 179447.0 140647.0 120812.0 138525.0 125981.0 114556.0 115237.0 True False 139139.06400758793 156441.56569500567 182726.36568423067 138078.266578513 121120.59179393857 113257.60654167915 150853.45664151662 106513.53120538112 120611.19628929085 111202.58770541292 1.251221458768402 1.406815874729781 1.6431844748819298 1.2416821355299439 1.0891886087651077 1.0184799551761348 1.3565642648635383 0.9578332069712838 1.0846078205374348 1.0 16.76283083467745 -5.986198007470028 6.442108592286323 1.0983554151895378 1.4343882189252142 0.5744584908837038 0.1344826620546179 0.11287933863118363 19.699087192909694 0.03881644401626534 0.056187644192467745 1.0322906471604589e-06 5.986198007470028 0.33603280373567634 SQGS(ph)GNEAEPLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SQGSGNEAEPLGK 13 0 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;Q9NUQ6-2 B8ZZZ7 SPATS2L SPATS2-like protein 1 S(0.002)QGS(0.998)GNEAEPLGK;S(0.003)QGS(0.997)GNEAEPLGK;S(0.028)QGS(0.972)GNEAEPLGK 107.73 0.00097513 16576400.0 60658.0 71129.0 51727.0 75829.0 79157.0 62166.0 72014.0 61739.0 64324.0 50875.0 True False 70926.20134988983 78190.21704481523 52960.36785573994 71580.54697093512 63646.75408327899 58905.90552301158 65192.312583789906 60118.41666787768 65264.616810947664 60098.234773721604 1.1801711251077018 1.3010401609833053 0.8812300070899461 1.1910590592293775 1.0590453167704188 0.980160328249252 1.0847625197187276 1.0003358150906108 1.0859656203993049 1.0 15.875034995767132 -5.242274970161905 24.99891626280509 1.0415371010871217 1.2406056615065224 0.5015679494737186 0.08166928571845271 642.9441683519478 838682.323220923 0.019478591594461452 0.05135824501668662 5.724334844328854e-06 5.242274970161905 0.1990685604194007 SQGS(ph)GNEAEPLGK ddPTM_PC-9_Lapatinib_30min_R1 2 SQGSGNEAEPLGK 13 0 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;Q9NUQ6-2 B8ZZZ7 SPATS2L SPATS2-like protein 1 SQGS(1)GNEAEPLGK;S(0.006)QGS(0.994)GNEAEPLGK 127.83 0.00011228 44958500.0 177044.0 189790.0 175410.0 142700.0 152585.0 159296.0 161798.0 191440.0 133424.0 125118.0 True False 174519.32009410684 189350.55291566314 160988.4669021812 153194.63403324518 143610.25029365227 152483.28141711274 170175.10875630577 200335.00128607947 118396.38410299287 146744.47959074425 1.1892734948587085 1.2903419157146012 1.0970665973341007 1.0439550057384765 0.978641586342239 1.0391074461020506 1.1596695782417656 1.365196168501833 0.806820020986061 1.0 17.16294670576628 -5.357899960339011 5.4493461241092405 1.0719662684367979 1.238757137568531 0.21423566866187105 0.13604360554504683 0.34369051680919566 15.2697760973791 0.035862944113010754 0.0768726298525773 4.386317248829317e-06 5.357899960339011 0.16679086913173302 SQGS(ph)PEDSAPQASPGPSK ddPTM_PC-9_AZD4547_30min_R2 1 SQGSPEDSAPQASPGPSK 18 0 Q9P107-2;Q9P107 Q9P107-2 GMIP GEM-interacting protein 1 S(0.001)QGS(0.965)PEDS(0.027)APQAS(0.007)PGPSK 203.64 4.7789e-20 4772800.0 21813.0 23077.0 30365.0 38675.0 32100.0 30388.0 23570.0 32222.0 23348.0 27522.0 True False 28749.080261414412 30536.188954668927 29962.340259861456 29759.076272793583 27643.46908633267 28487.833556174493 25667.68433885975 27242.83028789896 24582.12761411329 26558.46315704483 1.0824828263373556 1.1497724387929795 1.1281654394943301 1.1205119850807244 1.0408534907638296 1.0726461613279714 0.9664597001370996 1.0257683257802739 0.9255854703924274 1.0 14.696884045064882 -6.8340800357026295 0.9848315346717817 0.9742020145974758 1.1262070592292197 0.7592183772455288 0.03407349449917929 0.24216918311709193 0.5005677019921861 0.019299805231080446 0.016357823963669013 1.465277781471983e-07 6.8340800357026295 0.1520050446317439 SQGS(ph)PEDSAPQASPGPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQGSPEDSAPQASPGPSK 18 0 Q9P107-2;Q9P107 Q9P107-2 GMIP GEM-interacting protein 1 S(0.006)QGS(0.994)PEDSAPQASPGPSK 285.27 1.0219999999999998e-105 4916500.0 37835.0 37890.0 40264.0 41768.0 52217.0 39630.0 42296.0 41237.0 37299.0 32820.0 True False 44239.71822468736 41651.468793713626 41224.04646207035 39427.87437368306 41985.4536928709 37551.7330353722 38289.416683477924 40154.57244421312 37844.42731222467 38770.00619702295 1.1410810202058832 1.0743219534721646 1.063297391611865 1.0169684826284764 1.0829364710314349 0.9685769159937793 0.9876040898445374 1.0357123039948466 0.9761264189617448 1.0 15.242653345239873 -1.5228787452803967 0.3609807269095934 0.9934703742685789 2.818696248810415 0.6934185449571824 0.029074178131796174 36.191860889393254 0.5046988998238551 0.02347520674022108 45.429562167533504 0.029999999999995915 1.5228787452803967 1.8252258745418362 SQGS(ph)PEDSAPQASPGPSK ddPTM_PC-9_Lapatinib_30min_R1 2 SQGSPEDSAPQASPGPSK 18 0 Q9P107-2;Q9P107 Q9P107-2 GMIP GEM-interacting protein 1 S(0.014)QGS(0.876)PEDS(0.11)APQASPGPSK;SQGS(0.799)PEDS(0.037)APQAS(0.163)PGPSK 241.01 6.4264e-44 9503400.0 69547.0 53798.0 65441.0 55246.0 64241.0 53291.0 54578.0 52029.0 65809.0 50680.0 True False 68555.2470266423 53673.43403633924 60060.69358956516 59308.97513525343 60462.470682665415 51011.868157388504 57403.78178779504 54446.45728120275 58396.897420507914 59439.970473144786 1.153352642690424 0.902985543382615 1.0104428570788209 0.9977961742435498 1.0172022327969124 0.8582081678596369 0.9657437803359995 0.9159906515398064 0.9824516559423909 1.0 15.859145778766164 SQGS(ph)SQFR ddPTM_PC-9_AZD4547_30min_R2 2 SQGSSQFR 8 0 Q15172 Q15172 PPP2R5A Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform 1 S(0.001)QGS(0.99)S(0.009)QFR;S(0.011)QGS(0.978)S(0.011)QFR 105.17 0.0038465000000000005 68260000.0 29667.0 31832.0 37496.0 53905.0 50690.0 44202.0 39611.0 45973.0 33503.0 45752.0 True False 39100.488888065884 42121.071491312636 36998.77854054884 41478.03507394799 43652.56847309042 41438.04195241624 43136.30226332516 38868.929204443506 35273.90018226989 44150.23640582496 0.8856235452208624 0.9540395458846376 0.838019941738464 0.9394748126076985 0.9887278535009412 0.9385689709908126 0.9770344572296328 0.8803787333586132 0.7989515584477376 1.0 15.430133542465052 -1.5656716034547085 21.13746072947 0.9199640819091937 0.0058117264756477605 0.0 0.06354866260228456 0.0 0.0 0.014603779228772425 0.0 0.027184941110431304 1.5656716034547085 -0.9141523554335459 SQGS(ph)SQFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQGSSQFR 8 0 Q15172 Q15172 PPP2R5A Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform 1 S(0.016)QGS(0.79)S(0.193)QFR;S(0.002)QGS(0.916)S(0.081)QFR 85.92399999999999 0.012862 56977000.0 33209.0 30370.0 45648.0 38550.0 50351.0 36206.0 40772.0 35464.0 34624.0 33589.0 True False 38830.6277923521 33384.93289166227 46736.42144100404 36390.16848078628 40485.0829976778 34307.29362297968 36909.78099628243 34533.10757721399 35130.310497827464 39678.4198096223 0.9786334228697131 0.8413876624080223 1.1778801087655746 0.9171274626204092 1.020330023018202 0.8646335662454966 0.9302230576060276 0.8703246687470015 0.8853757449611972 1.0 15.276066951186131 -6.75975505751134 24.999971213773588 0.9032636763697438 0.985692849867161 0.15958690303079948 0.08757436302621818 80.70070150469505 1197822.4661056024 0.028785664059799886 0.027368391111632615 1.7387812264674524e-07 6.75975505751134 0.08242917349741719 SQGS(ph)SQFR ddPTM_PC-9_Lapatinib_30min_R1 2 SQGSSQFR 8 0 Q15172 Q15172 PPP2R5A Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform 1 SQGS(0.99)S(0.01)QFR;S(0.001)QGS(0.988)S(0.011)QFR 102.95 0.0041206 51576000.0 43375.0 27571.0 37811.0 30064.0 37834.0 32050.0 35074.0 31117.0 36602.0 24518.0 True False 42756.46454599917 27507.16104345719 34702.32553468082 32275.006850563987 35608.67850450589 30679.296212199064 36889.96010159995 32562.809418193443 32479.49732385286 28755.903631818554 1.486876054859529 0.9565743923630476 1.2067896032410723 1.1223784605694507 1.2383084517331846 1.0668868766917228 1.28286561861965 1.1323869294847173 1.1294897124329673 1.0 14.811570553554182 -14.522878745050264 0.1741783276617404 0.31570911392971396 1.2109258657428827 0.1659973675179519 0.1320174009280242 261.08844654168837 2.4774531120186394 61.75144709579144 0.41784441121765914 3.0000000015892942e-15 14.522878745050264 0.8952167518131688 SQGSPEDS(ph)APQASPGPSK ddPTM_PC-9_AZD4547_30min_R2 1 SQGSPEDSAPQASPGPSK 18 0 Q9P107-2;Q9P107 Q9P107-2 GMIP GEM-interacting protein 1 S(0.001)QGS(0.153)PEDS(0.843)APQAS(0.003)PGPSK 216.32 1.6314000000000002e-27 4437100.0 16865.0 18625.0 25051.0 30249.0 26104.0 24013.0 19389.0 23832.0 21281.0 24477.0 True False 22227.719186207964 24645.167018274 24718.80737196739 23275.560392391286 22479.910187838883 22511.46331395346 21114.583438529986 20149.312004878895 22405.870213977425 23620.067680218977 0.9410523071795828 1.0433995089232326 1.0465172118312163 0.9854146358726904 0.951729287662671 0.9530651486153896 0.8939256112383094 0.8530590291980101 0.948594666083095 1.0 14.527725478144655 -6.469362671756889 1.5693450709683365 0.9154724869690277 1.012736223153936 0.36379640505983646 0.04586601197955353 0.35494223159803945 1.769175819660022 0.017981236770304623 0.02065283953545982 3.393417758292584e-07 6.469362671756889 0.09726373618490836 SQGSPEDS(ph)APQASPGPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQGSPEDSAPQASPGPSK 18 0 Q9P107-2;Q9P107 Q9P107-2 GMIP GEM-interacting protein 1 SQGS(0.226)PEDS(0.462)APQAS(0.215)PGPS(0.096)K 122.83 5.3612e-05 4016200.0 13755.0 12826.0 14889.0 15193.0 15078.0 14200.0 14811.0 15932.0 14749.0 14922.0 True False 16083.449826366454 14099.280515918997 15244.010226846936 14341.785466370584 12123.57413832865 13455.327002328668 13407.994857645905 15513.801881349347 14964.676222633356 17627.24047751299 0.9124201741551127 0.7998575008893423 0.8647984490989198 0.8136148981836578 0.6877749329961573 0.7633257752110196 0.7606406047929304 0.880103831404595 0.8489517256954509 1.0 14.10551901977686 -8.698264091408062 1.2091038686286832 0.9979854882922532 0.8006896172000487 0.472750390824179 0.06089698511170195 0.6566650640058213 1.9194706729260322 0.061710804241505865 0.01899197550304931 2.0032534926068553e-09 8.698264091408062 -0.19729587109220448 SQHEPQFYEDSDHLSYRDSNR ddPTM_PC-9_AZD4547_30min_R2 1 SQHEPQFYEDSDHLSYRDSNR 21 1 D6RDY0;A0A0J9YWD4;F8W6W8;D6RA03;A0A590UK62;A0A590UJL1;Q9UQ26-4;Q9UQ26-5;Q9UQ26-2;Q9UQ26-3;Q9UQ26-1;Q9UQ26-8;Q9UQ26 D6RDY0 RIMS2 Regulating synaptic membrane exocytosis protein 2 0 44.577 0.016608 541860.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 False True 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SQIDVALS(ph)QDSTYQGER ddPTM_PC-9_AZD4547_30min_R2 2 SQIDVALSQDSTYQGER 17 0 Q92900-2;Q92900 Q92900-2 UPF1 Regulator of nonsense transcripts 1 1 SQIDVALS(0.702)QDS(0.283)T(0.015)YQGER;SQIDVALS(1)QDSTYQGER 212.85 2.6985e-19 15195400.0 32557.0 26553.0 36255.0 49370.0 46988.0 42022.0 32463.0 44058.0 41176.0 44258.0 True False 42909.44877233161 35135.737977784105 35774.23501140383 37988.509258896396 40464.52727191898 39394.3576970371 35352.14411083599 37249.84845212129 43352.47929752991 42708.54089108678 1.0047041616747614 0.8226864520468058 0.8376365538367027 0.8894827232747854 0.9474574974385014 0.9223999901447969 0.8277534978539606 0.8721873347795707 1.0150775089246264 1.0 15.382236989654261 -8.263650475646584 24.931879333851477 1.0075387728031633 0.8873447101976497 0.4279675622347564 0.05400587820039322 180.63762307851897 2036762.0310299709 0.044807212606210456 0.013794068776110873 5.449410501755609e-09 8.263650475646584 -0.12019406260551357 SQIDVALS(ph)QDSTYQGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SQIDVALSQDSTYQGER 17 0 Q92900-2;Q92900 Q92900-2 UPF1 Regulator of nonsense transcripts 1 1 SQIDVALS(0.867)QDS(0.131)T(0.002)YQGER;SQIDVALS(0.956)QDS(0.044)TYQGER;SQIDVALS(0.979)QDS(0.018)T(0.003)YQGER 201.52 7.8183e-13 51384000.0 67785.5 70489.1 91518.3 97946.9 106406.1 89553.4 99655.6 95157.4 87552.4 79941.4 True False 79260.2463253479 77486.79200176726 93700.44335708562 92459.2527411344 85556.58854758 84857.06205424924 90215.50012393591 92659.61907759917 88832.68821713216 94434.1430042259 0.8393176853609084 0.8205378853101865 0.9922305680572815 0.9790871161609088 0.9059921107533254 0.8985845516748313 0.9553271439112736 0.9812088735051334 0.9406840088881511 1.0 16.527020945038167 -5.252778724034002 24.98277064713046 0.9528408186496917 0.8299277680223608 0.7042837089942147 0.03276890672665953 362.3711013226598 1045300.4676239477 0.008931310773337434 0.02287578487173479 5.58754811566494e-06 5.252778724034002 -0.12291305062733093 SQIDVALS(ph)QDSTYQGER ddPTM_PC-9_Lapatinib_30min_R1 4 SQIDVALSQDSTYQGER 17 0 Q92900-2;Q92900 Q92900-2 UPF1 Regulator of nonsense transcripts 1 1 SQIDVALS(0.98)QDS(0.016)T(0.004)YQGER;SQIDVALS(0.994)QDS(0.006)TYQGER;SQIDVALS(0.961)QDS(0.039)TYQGER;SQIDVALS(0.998)QDS(0.002)TYQGER 260.11 4.1931e-58 75069700.0 103388.0 85385.3 95654.0 92379.0 106990.0 95010.0 83711.1 82774.4 104503.0 82672.0 True False 101913.66816096306 85187.59558390712 87789.69735511766 99172.85982731025 100697.05855043304 90946.6437791274 88045.25115644203 86620.40080680381 92732.77167462418 96961.74504648418 1.0510708951463785 0.8785691258244945 0.9054055010358015 1.0228039912005096 1.0385235796051124 0.9379641809821687 0.9080411157434561 0.8933461414630827 0.9563851355002676 1.0 16.56512804316285 -8.569236626048147 20.520548513692493 1.000000001817243 0.9515066449129376 0.04783380660391334 0.05955568009031133 9922.689888492792 4392325.78753661 0.06039569595490889 0.015594101652014263 2.696269965126058e-09 8.569236626048147 -0.04849335690430545 SQIDVALSQDS(ph)TYQGER ddPTM_PC-9_AZD4547_30min_R2 3 SQIDVALSQDSTYQGER 17 0 Q92900-2;Q92900 Q92900-2 UPF1 Regulator of nonsense transcripts 1 1 SQIDVALS(0.019)QDS(0.98)T(0.001)YQGER;SQIDVALS(0.004)QDS(0.996)TYQGER;SQIDVALS(0.069)QDS(0.882)T(0.049)YQGER 292.02 3.191699999999999e-98 127010600.0 99111.0 101964.0 136483.0 166241.0 158061.0 142299.0 127909.0 160564.0 131567.0 130895.0 True False 130626.236363134 134921.86898530406 134673.14624359185 127916.7058478468 136116.95848145906 133401.02103495027 139292.65320743373 135752.52319366307 138521.36302064604 126312.40589133701 1.0341520727228333 1.0681600752769567 1.066190967492515 1.0127010482081222 1.0776214538939004 1.0561197064816532 1.102763043934602 1.074736263914149 1.0966568330573327 1.0 16.946636816166794 SQIDVALSQDS(ph)TYQGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQIDVALSQDSTYQGER 17 0 Q92900-2;Q92900 Q92900-2 UPF1 Regulator of nonsense transcripts 1 1 SQIDVALS(0.086)QDS(0.913)T(0.002)YQGER;SQIDVALS(0.47)QDS(0.528)T(0.002)YQGER 275.69 1.2117999999999998e-82 61974000.0 83280.0 72456.0 103678.0 112509.0 124090.0 113377.0 103079.0 109575.0 95330.0 91375.0 True False 97377.65914502351 79648.95283497794 106150.07672100439 106205.48548909937 99775.4552875185 107431.3105311984 93314.61089266637 106698.77235430953 96724.0209033587 107940.56417589783 0.9021414691360959 0.7378963918067314 0.9834122837085074 0.9839256103574648 0.9243555103614836 0.9952820920606866 0.8644999366559054 0.9884955963398089 0.8960859306399319 1.0 16.71987760745332 -5.275570754818517 24.998405243798555 0.9523117752843118 0.8200189243787616 0.47039474489141464 0.05704262291010704 551.7176621200656 975988.6417110568 0.013824136153968887 0.02900676032163589 5.301872080279178e-06 5.275570754818517 -0.1322928509055502 SQIDVALSQDS(ph)TYQGER ddPTM_PC-9_Lapatinib_30min_R1 1 SQIDVALSQDSTYQGER 17 0 Q92900-2;Q92900 Q92900-2 UPF1 Regulator of nonsense transcripts 1 1 SQIDVALS(0.048)QDS(0.949)T(0.003)YQGER 260.11 4.1931e-58 56279000.0 30760.0 27533.0 33207.0 28480.0 33487.0 29943.0 27041.0 25077.0 32709.0 24013.0 True False 30321.35675930685 27469.24903012246 30476.84864272687 30574.51420649491 31517.360497975103 28662.4076905422 28441.050667370822 26242.16896808936 29024.967978960256 28163.61505468876 1.0766145148777293 0.9753452806673447 1.0821355349285318 1.0856033270986205 1.1190807869222033 1.0177105330720106 1.0098508523193253 0.9317755876556227 1.03058389069013 1.0 14.781544908366081 -6.973174689583101 8.662571177491355 0.9910517129721005 1.064895443467925 0.42095207590628236 0.04162922490316446 0.24999707337062485 71.96983581983328 0.015409018919983032 0.013487198196291648 1.0637150659337655e-07 6.973174689583101 0.07384373049582449 SQIDVALSQDST(ph)YQGER ddPTM_PC-9_Lapatinib_30min_R1 1 SQIDVALSQDSTYQGER 17 0 Q92900-2;Q92900 Q92900-2 UPF1 Regulator of nonsense transcripts 1 1 SQIDVALS(0.045)QDS(0.223)T(0.733)YQGER 159.64 7.1582e-05 9619800.0 21237.0 17997.0 24280.0 18418.0 16706.0 21261.0 16596.0 17017.0 21138.0 16501.0 True False 20934.156485611187 17955.32905223238 22283.79212351038 19772.52116064688 15723.385925259703 20351.7165918117 17455.25967514835 17807.671943612746 18757.215846992007 19353.17586379958 1.081691017171443 0.9277717093357326 1.1514281831744506 1.0216680352516039 0.8124447396083732 1.0515957037252943 0.9019325715837 0.9201421032360004 0.9692060868458119 1.0 14.240282712172148 -6.019411545662467 24.872825187250942 0.9397157573114681 1.0486283937336345 0.29901506891215324 0.07829231942456204 853.5110820693861 1093639.6904001422 0.021851302594004363 0.028670982025388154 9.562874457303628e-07 6.019411545662467 0.10891263642216642 SQIFSTASDNQPTVTIK ddPTM_PC-9_Lapatinib_30min_R1 1 SQIFSTASDNQPTVTIK 17 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 144.4 0.00050625 6887700.0 20138.0 20786.0 21537.0 25490.0 22020.0 26389.0 22064.0 21786.0 23696.0 21995.0 False True 19850.82842714309 20737.87129408804 19766.310995224176 27364.61963214731 20724.82689298568 25260.40398576353 23206.365960018873 22798.257093703185 21027.106950057838 25796.80644350473 0.7695072051114779 0.8038929678952389 0.766230930115811 1.0607754759131176 0.803387308362113 0.979206633235167 0.8995829003423758 0.8837627689935806 0.8151050400795702 1.0 14.654904855535479 -5.662770840615174 20.170977047642946 0.9123438946616654 0.7822493623605576 0.41627072089430195 0.07575389448725618 3.492808392334744 706.7251010739132 0.01942169207031072 0.0336393754622643 2.1738479266783453e-06 5.662770840615174 -0.1300945323011078 SQIHDIVLVGGSTR ddPTM_PC-9_AZD4547_30min_R2 2 SQIHDIVLVGGSTR 14 0 P11142;E9PKE3;P11142-2;E9PN89;E9PNE6;A8K7Q2 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 ; 112.24 0.00027153 31106000.0 51428.0 56679.0 134321.0 199040.0 157012.0 126600.0 94853.0 168713.0 103372.0 130170.0 False True 67781.03423114741 74999.37833174512 132539.8157762177 153154.40313734522 135213.59402440095 118683.68198669498 103294.73324539103 142642.2824890541 108836.03288187942 125612.78792066449 0.5396029763622243 0.5970680180995093 1.0551458810063847 1.2192580522460474 1.0764317571695028 0.9448375754676678 0.8223265716435714 1.1355713446878135 0.8664407078570611 1.0 16.938623818687027 -5.241136409035123 7.054985344006191 1.020136913981584 0.5648035279027521 0.7141679072567625 0.11301544845473191 0.09656486895870754 22.503716578440002 0.030613931996396143 0.07772769499331054 5.73936164326173e-06 5.241136409035123 -0.4553333860788318 SQIHDIVLVGGSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQIHDIVLVGGSTR 14 0 P11142;E9PKE3;P11142-2;E9PN89;E9PNE6;A8K7Q2 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 ; 101.42 0.0014383 22673000.0 63892.0 66230.0 128706.0 134049.0 161272.0 144306.0 140528.0 119755.0 132823.0 94139.0 False True 74707.65367547845 72804.87670117844 131774.83916022297 126538.66912272174 129671.90930073893 136738.33932380562 127216.17050538553 116611.55814091065 134765.2850985711 111205.65549608604 0.6717972511578589 0.6546868176478745 1.1849652661312795 1.1378798007910251 1.1660549881413436 1.2295987889628348 1.1439721292759522 1.0486117600827853 1.2118563979267607 1.0 16.762870634338896 -5.259266827722933 24.999183555952214 1.1462476804711448 0.663241981016319 0.8915214933297132 0.06654776052812686 49.682121246703026 571673.8257078876 0.016508786662573223 0.03952763438922001 5.504693876544763e-06 5.259266827722933 -0.48300569945482574 SQIHDIVLVGGSTR ddPTM_PC-9_Lapatinib_30min_R1 2 SQIHDIVLVGGSTR 14 0 P11142;E9PKE3;P11142-2;E9PN89;E9PNE6;A8K7Q2 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 ; 97.76700000000001 0.002199 55255000.0 103803.0 96429.0 137671.0 118424.0 151392.0 172400.0 131061.0 112171.0 157322.0 106333.0 False True 102322.75018486142 96205.72457508022 126352.22180542847 127133.29601088302 142487.42020812392 165026.85388402868 137846.69729360205 117382.87416036837 139602.73968589638 124712.51737018347 0.8204689660873205 0.7714199553001829 1.0131478737645707 1.019410871432528 1.1425270150323348 1.323258140914439 1.1053156507492545 0.9412276861667498 1.1193963735934729 1.0 16.928246749881716 -5.453228985612239 1.8419369241562877 1.1072827919997457 0.7822938679573525 0.5830109799866317 0.09837382537616807 0.2770979211199427 1.7810406720742564 0.03136665431617977 0.09574451833276618 3.5218512935097147e-06 5.453228985612239 -0.3249889240423932 SQLPTLEQDGGTQNPVS(ph)SPGMSQELR ddPTM_PC-9_AZD4547_30min_R2 1 SQLPTLEQDGGTQNPVSSPGMSQELR 26 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8;H0YCI3;P46937-4 P46937-6 YAP1 Transcriptional coactivator YAP1 1 SQLPTLEQDGGTQNPVS(0.582)S(0.413)PGMS(0.005)QELR 80.632 1.7558e-05 4404900.0 5102.6 5283.9 6806.4 13104.0 9181.2 8170.8 5422.8 11507.0 5576.7 7665.8 True False 6725.120659326698 6991.817342703784 6716.142688777247 10083.075254781823 7906.548859047902 7659.878584335611 5905.418694644404 9728.857554554446 5871.472976941305 7397.422675287925 0.9091167227462693 0.9451693717679375 0.907903060779995 1.363052470756562 1.0688248064370824 1.0354793717444934 0.7983075935855661 1.3151685366114052 0.7937187361965596 1.0 12.852806995775547 SQLPTLEQDGGTQNPVS(ph)SPGMSQELR ddPTM_PC-9_Lapatinib_30min_R1 1 SQLPTLEQDGGTQNPVSSPGMSQELR 26 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8;H0YCI3;P46937-4 P46937-6 YAP1 Transcriptional coactivator YAP1 1 SQLPTLEQDGGTQNPVS(0.486)S(0.486)PGMS(0.028)QELR 64.654 0.00029613 6994900.0 9110.0 7553.1 8533.6 8082.7 9458.2 10661.0 7971.2 9250.9 9318.8 8964.6 True False 8980.089729430607 7535.6112610110795 7832.0003486486075 8677.128721096784 8901.887271536656 10205.053882004813 8383.909732618855 9680.730586070818 8269.21861268564 10514.11916542135 0.8540981501297957 0.7167135108943852 0.7449031369557187 0.8252834673620565 0.8466602985453148 0.9706047383947306 0.7973953500728533 0.920736243689213 0.7864870544630405 1.0 13.360040370949864 -6.126817890742562 2.406106197088285 0.8842604677317937 0.76784726167179 0.34413563611655784 0.0715986441506695 0.33144831227498145 3.758493203010818 0.02179411497513494 0.03045145297100323 7.467618264758125e-07 6.126817890742562 -0.11641320606000372 SQLPTLEQDGGTQNPVSS(ph)PGMSQELR ddPTM_PC-9_AZD4547_30min_R2 1 SQLPTLEQDGGTQNPVSSPGMSQELR 26 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8;H0YCI3;P46937-4 P46937-6 YAP1 Transcriptional coactivator YAP1 1 SQLPTLEQDGGTQNPVS(0.252)S(0.746)PGMS(0.002)QELR 189.36 3.6402e-24 4521200.0 14803.0 13748.0 21577.0 26066.0 28869.0 24722.0 17880.0 27157.0 19132.0 23759.0 True False 19510.046078472362 18191.772143207036 21290.874881838656 20056.88641568552 24861.03766521302 23176.12943187263 19471.285361850336 22960.509655777794 20143.27846124789 22927.204641676766 0.8509561624886124 0.7934579216054222 0.9286293385778216 0.874807318604658 1.0843466551531085 1.01085718010923 0.8492655631666363 1.00145264172504 0.8785754206001942 1.0 14.484772847183837 -5.562370242161452 1.8177044572459726 0.9634897713858859 0.8226489116292612 0.36122975420030246 0.070310578632477 0.4006072475803316 2.597641646792637 0.02127856928998068 0.05591834128482392 2.739237937318076e-06 5.562370242161452 -0.14084085975662464 SQLPTLEQDGGTQNPVSS(ph)PGMSQELR ddPTM_PC-9_Lapatinib_30min_R1 1 SQLPTLEQDGGTQNPVSSPGMSQELR 26 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8;H0YCI3;P46937-4 P46937-6 YAP1 Transcriptional coactivator YAP1 1 SQLPTLEQDGGTQNPVS(0.482)S(0.513)PGMS(0.005)QELR 183.1 6.7102e-20 6542400.0 14119.0 15740.0 11951.0 9758.7 16932.0 15121.0 17127.0 13698.0 18661.0 15965.0 True False 13917.660470892512 15703.554997062716 10968.43491219409 10476.387352068887 15936.093049592808 14474.31007877261 18013.752256945387 14334.459087007537 16559.201670958362 18724.528977974674 0.7432849438970457 0.8386622176469445 0.5857789493714936 0.5595007150456 0.8510811176258771 0.7730133076136911 0.9620403417428891 0.7655444419386411 0.8843587836274361 1.0 14.192641807195448 -6.376151903039636 8.389609234379447 0.8614318684822869 0.6863587942482197 0.4654364121137179 0.0997689947288394 0.31461879280726596 21.029128451127388 0.03193153096621657 0.03619955202174554 4.2057949670111945e-07 6.376151903039636 -0.17507307423406726 SQLQALHIGLDSS(ph)SIGSGPGDAEADDGFPESR ddPTM_PC-9_Lapatinib_30min_R1 1 SQLQALHIGLDSSSIGSGPGDAEADDGFPESR 32 0 E9PF63;O75116;Q14DU5 E9PF63 ROCK2 Rho-associated protein kinase 2 1 SQLQALHIGLDS(0.092)S(0.439)S(0.439)IGS(0.03)GPGDAEADDGFPESR 68.733 0.00067779 0.0 1725.7 3107.2 4248.8 3463.9 3148.0 2890.4 3514.4 3061.7 4742.6 3529.0 True False 1701.0912015453796 3100.0054693057987 3899.48006484229 3718.64676123166 2962.8408292061285 2766.7843298514886 3696.3584359087354 3203.957759285367 4208.438446207984 4138.982947903077 0.41099256096408887 0.7489775890176951 0.9421348466337303 0.8984445715379498 0.715837892182471 0.6684696131094761 0.8930595951793937 0.774093007778295 1.0167808128661404 1.0 12.015060589517716 -4.792885944853906 3.360839143262017 0.8458393532320222 0.3595763662167654 0.6009305041662734 0.11015477703279068 0.21434024984870645 3.8927780903426354 0.02830679740908354 0.26724745321929433 1.6110686811876316e-05 4.792885944853906 -0.4862629870152568 SQNHS(ph)RSPSEER ddPTM_PC-9_AZD4547_30min_R2 1 SQNHSRSPSEER 12 1 A0A024QZ33;Q9H0G5 A0A024QZ33 CCDC55;NSRP1 Nuclear speckle splicing regulatory protein 1 1 S(0.021)QNHS(0.615)RS(0.311)PS(0.053)EER 51.358999999999995 0.043008 922330.0 0.0 0.0 2127.5 8743.4 5465.9 2352.4 562.38 2343.8 897.38 3475.5 True False 0.0 0.0 2099.2879599161943 6727.74421418341 4707.054133301735 2205.304056125605 612.4307305255811 1981.61956516596 944.8136747624197 3353.823802859867 0.0 0.0 0.625938654894778 2.0059921479615412 1.4034887966648528 0.657549169471903 0.18260670998975861 0.5908538079657604 0.28171237676730654 1.0 11.711591181847743 -3.0854140317753997 9.197053788906464 0.6864126188418578 0.550006758923939 0.0 0.6105222646059515 0.0 0.0 0.1557501369745534 0.0 0.0008214591438829355 3.0854140317753997 -0.13640585991791876 SQNHSRS(ph)PSEER ddPTM_PC-9_AZD4547_30min_R2 1 SQNHSRSPSEER 12 1 A0A024QZ33;Q9H0G5 A0A024QZ33 CCDC55;NSRP1 Nuclear speckle splicing regulatory protein 1 1 SQNHS(0.002)RS(0.977)PS(0.022)EER 76.311 0.008867 3791000.0 2600.4 0.0 9037.8 32573.0 18134.0 8946.2 3259.5 7785.6 6204.7 15274.0 True False 3427.273108319905 0.0 8917.952866806389 25063.79809783336 15616.407115624817 8386.792699758067 3549.58918551181 6582.514415289747 6532.667774853897 14739.261909043782 0.23252677979872138 0.0 0.6050474522970836 1.7004785078454034 1.0595107958589727 0.5690103582874839 0.2408254366749421 0.4465972893290416 0.44321539403852733 1.0 13.847376660642977 -5.364870927323074 5.2836428208431645 0.7647141777189036 0.12195846215096544 0.30079241722668215 0.39633046314521897 0.29706640479335095 12.176572191533763 0.11876718839557156 0.25513347352165566 4.316473437115893e-06 5.364870927323074 -0.6427557155679382 SQNHSRS(ph)PSEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQNHSRSPSEER 12 1 A0A024QZ33;Q9H0G5 A0A024QZ33 CCDC55;NSRP1 Nuclear speckle splicing regulatory protein 1 1 SQNHS(0.01)RS(0.798)PS(0.192)EER;S(0.001)QNHS(0.028)RS(0.791)PS(0.181)EER 66.568 0.018377 3618800.0 645.44 379.93 7091.8 9967.6 13029.9 18305.1 5657.3 13880.099999999999 14388.7 6979.299999999999 True False 754.7002439789139 417.6469395301034 7260.895407801275 9409.147687395214 10476.784630919788 17345.148331713128 5121.399588694903 13515.762082181585 14599.107516753982 8244.591841891599 0.09153882429257519 0.050657078911777946 0.8806858540780559 1.141250879101909 1.270746306407334 2.1038213491152695 0.6211829144376266 1.6393488412011668 1.7707495770226551 1.0 13.009232357796698 -5.4877162158949 1.588515554381031 1.4177839186145798 3.976521637640625e-16 0.6344426040360036 0.39025924883753765 0.26900373091618024 1.2701620044638284 0.11759632281828826 0.38289545581275025 3.252997908880436e-06 5.4877162158949 -1.4177839186145793 SQNRPQGQSTQPSNAAGTNT(ph)TSASTPR ddPTM_PC-9_Lapatinib_30min_R1 1 SQNRPQGQSTQPSNAAGTNTTSASTPR 27 1 Q9UHD9 Q9UHD9 UBQLN2 Ubiquilin-2 1 SQNRPQGQSTQPSNAAGT(0.044)NT(0.227)T(0.227)S(0.167)AS(0.167)T(0.167)PR 75.539 3.7398000000000003e-05 2770700.0 0.0 863.19 1800.1 1286.8 1946.6 2004.3 1152.0 1274.9 2970.1 780.0 True False 0.0 861.1913365892352 1652.1027265869434 1381.4355646389618 1832.1048151628493 1918.5807612515011 1211.6449232207092 1334.136508251271 2635.5760614604483 914.8219607153304 0.0 0.9413758890482258 1.8059281450732863 1.5100594694499576 2.0026900247675123 2.097217648504303 1.3244598132223266 1.4583564513559164 2.8809715711236334 1.0 9.837347188487604 -4.9875538171905145 2.3378582778738477 1.7785538174821685 3.9949541702356384e-14 0.5629925312576877 0.4882363861834779 0.27873613608283776 2.5077718831186604 0.12603307937847982 0.8530599571472541 1.0290729979453732e-05 4.9875538171905145 -1.7785538174821285 SQNRPQGQSTQPSNAAGTNTTS(ph)ASTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQNRPQGQSTQPSNAAGTNTTSASTPR 27 1 Q9UHD9 Q9UHD9 UBQLN2 Ubiquilin-2 1 SQNRPQGQSTQPSNAAGT(0.019)NT(0.052)T(0.131)S(0.334)AS(0.131)T(0.334)PR 79.877 1.2075e-05 995980.0 0.0 913.35 0.0 0.0 0.0 0.0 454.95 0.0 0.0 0.0 True False 0.0 1004.0213518801351 0.0 0.0 0.0 0.0 411.8538424472357 0.0 0.0 0.0 0.0 SQNRPQGQSTQPSNAAGTNTTSAS(ph)TPR ddPTM_PC-9_AZD4547_30min_R2 1 SQNRPQGQSTQPSNAAGTNTTSASTPR 27 1 Q9UHD9 Q9UHD9 UBQLN2 Ubiquilin-2 1 SQNRPQGQSTQPSNAAGT(0.008)NT(0.008)T(0.108)S(0.108)AS(0.48)T(0.288)PR 78.642 1.5607e-05 1359200.0 0.0 0.0 437.81 0.0 0.0 562.66 655.96 1739.3 0.0 570.21 True False 0.0 0.0 432.0043533400278 0.0 0.0 527.4767812530316 714.3391692370998 1470.5311501378758 0.0 550.2471214584161 0.0 0.0 0.7851097016100896 0.0 0.0 0.9586179748745758 1.2982151861944535 2.6724922181151443 0.0 1.0 9.103935882652065 -6.932713933683737 3.4733875984415308 1.3639104916802784 0.17575926682792425 0.38407081447616376 0.6497632670089604 0.2312061608715165 5.641491167942828 0.23832126914602936 0.203496444738558 1.1675784384430519e-07 6.932713933683737 -1.1881512248523542 SQNRPQGQSTQPSNAAGTNTTSAS(ph)TPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQNRPQGQSTQPSNAAGTNTTSASTPR 27 1 Q9UHD9 Q9UHD9 UBQLN2 Ubiquilin-2 1 SQNRPQGQSTQPSNAAGT(0.004)NT(0.014)T(0.036)S(0.096)AS(0.425)T(0.425)PR 100.42 7.8359e-10 3200300.0 1074.9 1054.8 1208.5 471.81 571.54 405.2 955.13 663.86 1074.1 442.17 True False 1256.8593397572733 1159.5135730696518 1237.3152232617715 445.37601532865847 459.55083983421906 383.9505986861673 864.653171857629 646.4343784178119 1089.806680502439 522.331920784206 2.4062464684721556 2.2198788297847267 2.3688294244091406 0.8526685764484596 0.8798061568672078 0.7350701410507727 1.6553711106904534 1.2375930949180436 2.0864255794787563 1.0 9.028823062257404 -5.751849635787657 24.991603710579792 1.2020268510068028 2.3204747015220555 0.6401661032672188 0.3864586762474742 132.38658060899817 345006.09122788906 0.11059225793136682 0.18844396866713212 1.7707219228649286e-06 5.751849635787657 1.1184478505152526 SQNRPQGQSTQPSNAAGTNTTSAS(ph)TPR ddPTM_PC-9_Lapatinib_30min_R1 1 SQNRPQGQSTQPSNAAGTNTTSASTPR 27 1 Q9UHD9 Q9UHD9 UBQLN2 Ubiquilin-2 1 SQNRPQGQSTQPSNAAGTNT(0.002)T(0.006)S(0.019)AS(0.486)T(0.486)PR 114.19 3.9744e-12 2210100.0 522.57 710.74 1372.0 1522.2 524.69 1056.4 1341.6 422.69 1253.3 550.97 True False 515.1180559723986 709.0943251977358 1259.1994560731564 1634.147665910342 493.8287657802298 1011.220234588677 1411.0614835007837 442.3297205057099 1112.1401561659131 646.2044303786226 0.7971441106811691 1.0973219802629097 1.948608515938786 2.5288400838614895 0.7641989787827465 1.5648611910571166 2.1836146847121083 0.6845043142872621 1.7210345579250987 1.0 9.335846831531448 -7.775453586124642 24.999941456661922 1.1520774920031744 1.5599077816075422 0.09603210553688335 0.5893526111450158 662.7415901237588 1182247.2385354026 0.32815422580689185 0.15887418360067526 1.677051555853618e-08 7.775453586124642 0.40783028960436774 SQNRPQGQSTQPSNAAGTNTTSAST(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 SQNRPQGQSTQPSNAAGTNTTSASTPR 27 1 Q9UHD9 Q9UHD9 UBQLN2 Ubiquilin-2 1 SQNRPQGQSTQPSNAAGT(0.005)NT(0.023)T(0.014)S(0.044)AS(0.222)T(0.691)PR;SQNRPQGQSTQPSNAAGT(0.004)NT(0.011)T(0.026)S(0.066)AS(0.25)T(0.643)PR;SQNRPQGQSTQPSNAAGTNTT(0.001)S(0.005)AS(0.244)T(0.75)PR 151.53 2.2777000000000003e-10 9606100.0 2966.8 4626.1900000000005 4632.5 7492.1 6849.9 6950.44 6014.619999999999 11599.81 9252.62 6617.77 True False 3910.180686726463 6121.515447423842 4571.070023178269 5764.912096791125 5898.909622880688 6515.827888053752 6549.909528137154 9807.325901616075 9741.694603601894 6386.083886592419 0.6122971066721948 0.9585710986784814 0.7157860911873127 0.902730405545495 0.9237131437100987 1.0203166766621607 1.0256535373562328 1.5357339608717877 1.5254567238076184 1.0 12.640715788709462 -7.341533449664063 1.5185984073736463 1.386173630603719 0.8289449910616161 0.5929860734038297 0.1812822817464686 0.2602237711622287 1.1639681095542365 0.10714300150184156 0.05972184374789089 4.554771036503442e-08 7.341533449664063 -0.5572286395421028 SQNRPQGQSTQPSNAAGTNTTSAST(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQNRPQGQSTQPSNAAGTNTTSASTPR 27 1 Q9UHD9 Q9UHD9 UBQLN2 Ubiquilin-2 1 SQNRPQGQSTQPSNAAGT(0.003)NT(0.014)T(0.01)S(0.023)AS(0.257)T(0.693)PR 131.68 1.5069999999999997e-12 3082000.0 1820.6 2241.8 2995.6 2986.1 3506.3 1234.3 3295.1 2620.9 1356.5 1224.3 True False 2128.7916215109244 2464.351088459942 3067.0264648762654 2818.7984980668207 2819.2656851851534 1169.5711351390332 2982.9642735418984 2552.1041520730937 1376.3362462541284 1446.2558984465331 1.471932888085382 1.7039523165346986 2.1206665211672777 1.9490316347850867 1.9493546669115827 0.8086889300816713 2.0625425118376284 1.764628344689474 0.9516547159686556 1.0 10.498107127930693 SQNRPQGQSTQPSNAAGTNTTSAST(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 SQNRPQGQSTQPSNAAGTNTTSASTPR 27 1 Q9UHD9 Q9UHD9 UBQLN2 Ubiquilin-2 1 SQNRPQGQSTQPSNAAGT(0.009)NT(0.041)T(0.041)S(0.041)AS(0.195)T(0.672)PR;SQNRPQGQSTQPSNAAGTNT(0.001)T(0.003)S(0.011)AS(0.205)T(0.779)PR 108.71 2.7525e-10 896330.0 0.0 611.62 491.06 385.07 953.04 476.06 645.68 0.0 1510.96 0.0 True False 0.0 610.2038314678209 450.68694234641697 413.3893323558635 896.9840609487316 455.7000235500621 679.1101510634963 0.0 1340.7797736858297 0.0 0.0 SQPAPVS(ph)PQQK ddPTM_PC-9_AZD4547_30min_R2 2 SQPAPVSPQQK 11 0 Q13118-2;Q13118 Q13118-2 KLF10 Krueppel-like factor 10 1 SQPAPVS(1)PQQK;SQPAPVS(1)PQQK 121.24 0.00078747 25067000.0 81322.0 67994.0 88915.0 118026.0 106865.0 79572.0 87836.0 86685.0 84112.0 90862.0 True False 107180.70439732024 89971.73080486016 87735.92900397113 90816.92918352253 92028.63937417253 74596.35026102114 95653.2338391212 73289.82507313375 88557.98860194877 87680.94903624027 1.2223944377360734 1.026126334098791 1.000627045764618 1.0357658098110467 1.0495853476236356 0.8507703335896717 1.090923796908104 0.8358694320569182 1.010002624006111 1.0 16.41997579329574 -1.5228787769392491 0.8539070674430043 0.9723380820708621 88.3011014842229 0.45853633754380174 0.07716374186641933 594.2818703344535 1.6238929883380822 0.02514073536990868 100842.81689622668 0.029999997813079948 1.5228787769392491 87.32876340215203 SQPAPVS(ph)PQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SQPAPVSPQQK 11 0 Q13118-2;Q13118 Q13118-2 KLF10 Krueppel-like factor 10 1 SQPAPVS(1)PQQK;S(0.112)QPAPVS(0.888)PQQK;SQPAPVS(1)PQQK;SQPAPVS(1)PQQK;SQPAPVS(1)PQQK 137.81 9.5054e-05 22077800.0 80395.0 88066.0 92666.0 120987.0 127127.0 115940.0 113268.0 118783.0 111926.0 88894.6 True False 94004.28562637093 96808.6104720818 94875.50887776219 114208.49063514637 102217.37693880525 109859.90229929476 102538.43505069445 115665.07211099159 113562.70600681129 105010.48729073368 0.8951895001316315 0.9218946885186425 0.9034860357812489 1.0875912833253212 0.9734016056492016 1.04618029240389 0.9764589965838834 1.1014621024542002 1.081441567758845 1.0 16.680173890012036 -5.748667996417981 24.962605967232193 1.0373796043267507 0.9083604797350869 0.6647740554818344 0.042695253958096806 136.35202203958968 266507.6063607117 0.011643859638743785 0.020003067294436853 1.783741857255798e-06 5.748667996417981 -0.12901912459166376 SQPAPVS(ph)PQQK ddPTM_PC-9_Lapatinib_30min_R1 2 SQPAPVSPQQK 11 0 Q13118-2;Q13118 Q13118-2 KLF10 Krueppel-like factor 10 1 SQPAPVS(1)PQQK;SQPAPVS(1)PQQK 128.76 0.00029352 21088000.0 145614.0 124464.0 143532.0 142070.0 132833.0 116677.0 115700.0 112870.0 142483.0 106100.0 True False 143537.5176576626 124175.81125504528 131731.3530095422 152518.30173162703 125020.02409972595 111686.99669737132 121690.37987555214 118114.35225219313 126435.06412749375 124439.24363063675 1.1534746874845507 0.9978830442237869 1.0585997565249596 1.2256447185128765 1.0046671809643355 0.897522304369537 0.9779099930626078 0.9491728558137391 1.016038513563945 1.0 16.925082005427484 -6.50789246498758 24.535597250678414 0.9639557318567653 1.09960009373979 0.5271741185762857 0.0629726652074769 445.9757947171289 730154.4969875775 0.0199684047896481 0.02187695946864133 3.10532839870068e-07 6.50789246498758 0.13564436188302476 SQPDKLQTLS(ph)PALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQPDKLQTLSPALK 14 1 Q13415 Q13415 ORC1 Origin recognition complex subunit 1 1 SQPDKLQT(0.08)LS(0.92)PALK 60.333999999999996 0.026519 3997500.0 22260.0 23826.0 28989.0 28935.0 35525.0 29285.0 35279.0 31601.0 27900.0 21424.0 True False 26028.178344959448 26191.287819451598 29680.207701394702 27313.865758535718 28564.1312683463 27749.243046703876 31937.117722158546 30771.507234027184 28307.984718385684 25308.001607709324 1.028456483779847 1.0349014602351378 1.172759831513268 1.0792581011301725 1.1286600858933522 1.0964612487716494 1.261937557030574 1.2158805626380855 1.1185389173423517 1.0 14.627305972163109 -4.623090267580208 0.7204387096278806 1.152322073722359 0.9040463382363451 0.19325578395189547 0.07187608732580957 5.06490273038483 1.7062746704833485 0.029853496440265203 1.0781912145419503 2.381824358608398e-05 4.623090267580208 -0.2482757354860139 SQPDPVDT(ph)PTSSKPQSK ddPTM_PC-9_AZD4547_30min_R2 2 SQPDPVDTPTSSKPQSK 17 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 SQPDPVDT(0.993)PT(0.006)SSKPQSK;SQPDPVDT(0.713)PT(0.13)S(0.067)S(0.067)KPQS(0.023)K 96.391 0.0011220999999999998 30494000.0 142831.0 150245.0 176972.0 221830.0 197462.0 215070.0 131452.0 209497.0 168647.0 223480.0 True False 188248.28693064168 198808.75804889022 174625.2356485492 170690.52073933548 170047.8097422247 201621.63890109357 143150.97334373335 177124.0524121397 177561.3361203258 215656.03322201775 0.8729099024873568 0.9218789526941578 0.8097396258270809 0.791494298532375 0.7885140387756302 0.9349223199961404 0.6637930374818659 0.8213266736191451 0.8233543642042536 1.0 17.718372552103155 -5.268898765344141 24.330363287520843 0.8178386914113732 0.8973944292539312 0.08047326558916479 0.08572194214480701 720.8825401534029 2351322.0760398903 0.021202420816987946 0.04560353895765926 5.3839526858619245e-06 5.268898765344141 0.07955573784255798 SQPDPVDT(ph)PTSSKPQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQPDPVDTPTSSKPQSK 17 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 SQPDPVDT(0.986)PT(0.011)S(0.002)SKPQSK;SQPDPVDT(0.915)PT(0.067)S(0.014)S(0.004)KPQS(0.001)K 81.807 0.0035043 25885000.0 103160.0 91722.0 100973.0 106022.0 104702.0 89115.0 96455.0 83139.0 67386.0 61838.0 True False 120622.95049712539 100827.55399041972 103380.57926223469 100081.93106796153 84186.39470959578 84441.65252200841 87318.08412627362 80956.68934305178 68371.39276821287 73048.73989066132 1.6512666841025965 1.3802778000186926 1.4152274141480576 1.3700706024191962 1.1524688151445897 1.1559631644351416 1.195340046343996 1.1082557955719292 0.9359695029722694 1.0 16.156571765936555 -3.3859428483166023 0.23910956732551986 0.9479662908372084 2.785639375343831 0.8887056698975255 0.06840405204790714 6.64723776475091 0.1900834084966576 0.10133364468630439 4.035088065671638 0.00041120383057599515 3.3859428483166023 1.8376730845066225 SQPDPVDT(ph)PTSSKPQSK ddPTM_PC-9_Lapatinib_30min_R1 2 SQPDPVDTPTSSKPQSK 17 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(0.01)QPDPVDT(0.977)PT(0.01)S(0.002)SKPQSK;S(0.042)QPDPVDT(0.944)PT(0.01)S(0.002)S(0.002)KPQSK 106.49 0.00047042 33250000.0 187012.0 177615.0 221428.0 152587.0 149879.0 167517.0 144366.0 134678.0 153152.0 108982.0 True False 184345.1745861992 177203.7433801328 203223.04457679766 163808.75699531016 141063.41189345153 160352.68841119992 151840.565091737 140935.63154621114 135902.40899794298 127819.39349061316 1.44223164851535 1.3863603835136828 1.5899233991571242 1.2815641861681968 1.1036150934624094 1.2545254990822339 1.1879305709809045 1.1026153989422678 1.0632377864312383 1.0 16.963747221285622 -6.3374019188712 0.49261240468783124 1.0332191528920511 1.5348538928440119 0.7544430214097091 0.08804970251044857 0.690193925952161 0.3302277162411864 0.08062134500551983 0.16693281388066405 4.5983082506544604e-07 6.3374019188712 0.5016347399519607 SQPEPS(ph)PVLSQLSQR ddPTM_PC-9_AZD4547_30min_R2 1 SQPEPSPVLSQLSQR 15 0 Q5T6F2;A2A305 Q5T6F2 UBAP2 Ubiquitin-associated protein 2 1 S(0.042)QPEPS(0.896)PVLS(0.054)QLS(0.008)QR 80.545 0.0097368 6342300.0 7481.9 7460.1 10394.0 17480.0 12443.0 11008.0 9565.5 12930.0 11089.0 9936.6 True False 9860.98856681229 9871.431434793327 10256.16876868105 13450.256063307868 10715.504231814248 10319.668019822584 10416.810969171107 10931.965601841399 11675.141901357812 9588.722658465653 1.0283943876618706 1.029483465775087 1.0696074059067842 1.4027161429507986 1.1175111235857662 1.0762296905846576 1.0863606488789572 1.1400857018416137 1.2175909469078356 1.0 13.227122927117694 -5.537992570728187 24.99846946508144 1.1543843481665639 1.0340904188567295 0.19377469320444907 0.10092145971878091 355.03581957325116 587231.8727286939 0.02791382493229842 0.048370519779173185 2.897393151621787e-06 5.537992570728187 -0.1202939293098344 SQPEPS(ph)PVLSQLSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQPEPSPVLSQLSQR 15 0 Q5T6F2;A2A305 Q5T6F2 UBAP2 Ubiquitin-associated protein 2 1 S(0.001)QPEPS(0.999)PVLSQLSQR 93.181 0.017064 0.0 6500.9 3438.6 6914.8 9932.2 11901.0 9430.1 9330.4 6370.3 9787.4 3385.7 True False 7601.3739713722725 3779.96148308429 7079.675056525036 9375.731034626862 9569.08448204333 8935.568955257719 8446.556965753794 6203.086374890771 9930.522209058356 3999.5006088135488 1.9005807761652571 0.9451083654680615 1.770139762180264 2.344225430036419 2.3925698275820486 2.23417117016228 2.1119029078631555 1.550965228314071 2.4829405419203683 1.0 11.965604156120488 -3.606577150339738 11.368057593417053 1.9040804083780951 1.6777496062965802 0.0 0.52907562292116 0.0 0.0 0.12322255499075255 0.0 0.00024741319045804423 3.606577150339738 -0.2263308020815149 SQPLTS(ph)PESR ddPTM_PC-9_AZD4547_30min_R2 1 SQPLTSPESR 10 0 P46939;P46939-2 P46939 UTRN Utrophin 1 SQPLT(0.408)S(0.59)PES(0.002)R 106.54 0.0023011 12421000.0 37756.0 37430.0 48776.0 58885.0 51550.0 47861.0 41399.0 57176.0 40421.0 50999.0 True False 49761.62262641375 49528.515516456144 48129.19837032775 45309.97301418098 44393.17231777099 44868.244103990626 45083.43079951021 48340.76297377291 42557.57153889299 49213.54053288746 1.0111368149414088 1.0064001691436566 0.9779665890562154 0.9206810264728285 0.9020519929490703 0.9117052668463663 0.9160777767936192 0.9822654995014775 0.8647532991545985 1.0 15.586767690479952 -5.593563070904536 3.032605505527637 0.9250964539188102 1.0074180314804222 0.4474644218375443 0.03662715179800362 0.21145723441081854 3.906211150948643 0.009792693930274345 0.019523436003792183 2.549393822328962e-06 5.593563070904536 0.08232157756161196 SQPLTS(ph)PESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQPLTSPESR 10 0 P46939;P46939-2 P46939 UTRN Utrophin 1 SQPLT(0.49)S(0.51)PESR 86.288 0.011362 9711400.0 31098.0 30068.0 37595.0 33807.0 40435.0 30206.0 35439.0 33789.0 29175.0 25085.0 True False 36362.27718650262 33052.95232751072 38491.407379831464 31912.90339377282 32512.0520150762 28621.944185376047 32081.96136385885 32902.07455240479 29601.629181322653 29632.71192724928 1.2270992029273249 1.1154211065345085 1.298949872503435 1.0769484572360977 1.0971676198552442 0.9658901370770672 1.0826535702376034 1.110329511290835 0.9989510664429588 1.0 14.854903044490458 -5.907654497321136 7.1525594958743905 1.0498179475086649 1.2034877686378451 0.615209235281124 0.06047537485725301 0.15507370269468618 10.2620702935801 0.0166028152758648 0.0247589848195909 1.2369310818007087e-06 5.907654497321136 0.15366982112918026 SQPS(ph)ETER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQPSETER 8 0 P26006 P26006 ITGA3 Integrin alpha-3;Integrin alpha-3 heavy chain;Integrin alpha-3 light chain 1 SQPS(0.829)ET(0.171)ER 87.568 0.030432999999999998 0.0 8795.2 12293.0 10917.0 11340.0 17562.0 11668.0 9900.3 9949.5 9340.7 10941.0 True False 10284.053646881735 13513.367798393285 11177.30268295306 10704.656564776047 14120.85216987186 11056.10953965992 8962.471912035093 9688.336167366648 9477.290066631727 12924.51669109166 0.7957012159665601 1.045560783538428 0.8648139771955355 0.8282442446884167 1.0925632661842424 0.8554369810424279 0.6934473548409402 0.7496091651956642 0.7332800361629024 1.0 13.657822711896067 -7.002046618341882 24.998754703556536 0.7733930704384022 0.9283634866660733 0.21705186883482797 0.11501095706865239 100.68085588919179 1229798.120744528 0.039046290173309725 0.03390798847511579 9.952985735819046e-08 7.002046618341882 0.15497041622767105 SQPVT(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 2 SQPVTPEK 8 0 P54274-2;P54274 P54274-2 TERF1 Telomeric repeat-binding factor 1 1 S(0.002)QPVT(0.998)PEK;S(0.002)QPVT(0.998)PEK 101.71 0.011008 22057000.0 119580.0 126589.0 141614.0 129520.0 132167.0 155415.0 139934.0 166861.0 152069.0 147819.0 True False 157603.95258148483 167506.4186671833 139736.105831056 99661.16506405236 113817.89341848406 145696.8754815337 152387.85491192213 141076.46653432804 160107.05688498338 142643.90180260176 1.104876903883249 1.174297790164122 0.9796149997665534 0.6986710529130702 0.7979162935124372 1.0214027633873672 1.0683096366979963 0.9890115508026216 1.1224248275720057 1.0 17.122058545736387 -9.505111877217558 15.0879181234722 1.000002729659944 0.9882000453924246 0.0 0.13924490096282446 0.0 0.0 0.15119395770327446 0.03666992103328057 3.1252741714961604e-10 9.505111877217558 -0.011802684267519514 SQPVT(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQPVTPEK 8 0 P54274-2;P54274 P54274-2 TERF1 Telomeric repeat-binding factor 1 1 SQPVT(1)PEK 91.31299999999999 0.021562 9586700.0 45687.0 52403.0 54784.0 53504.0 60663.0 62527.0 62709.0 57890.0 49184.0 44149.0 True False 53420.906740618244 57605.22352063805 56090.258329476965 50506.34434230844 48776.52062298922 59247.97404750739 56768.74954615604 56370.44883952511 49903.222953013676 52152.8642167083 1.0243139574969633 1.1045457308207238 1.0754971787629495 0.9684289655203182 0.9352606296043584 1.1360444903144173 1.0885068423139248 1.080869664325466 0.956864473361486 1.0 15.670458866767545 -8.26512008532301 24.84943253621531 0.9784322323193426 1.0516228740426885 0.19764923487822328 0.05903485139476204 535.4530920094347 3614897.97136942 0.053717627375362884 0.01604455371227891 5.431001399152128e-09 8.26512008532301 0.07319064172334588 SQPVT(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 2 SQPVTPEK 8 0 P54274-2;P54274 P54274-2 TERF1 Telomeric repeat-binding factor 1 1 SQPVT(1)PEK;S(0.001)QPVT(0.999)PEK 98.40700000000001 0.013486000000000001 23411000.0 79051.0 87649.0 84847.0 80571.0 89393.0 86639.0 83341.0 87024.0 87499.0 75812.0 True False 77923.71824382205 87446.0541256384 77871.20717889126 86496.46011697673 84135.0794934001 82933.65193537329 87655.98918935521 91067.45273673111 77643.94121468221 88916.00318685963 0.8763745045991669 0.9834681158786222 0.8757839352635161 0.9727884409649166 0.9462310099182902 0.9327190715161336 0.9858291651407626 1.024196426658429 0.8732279728263445 1.0 16.440155479600236 -1.522878745280338 0.19810726611604687 0.9836738042751558 0.6234088434758048 0.1638682966012155 0.048366144751632 100.94241445886095 1.2122715229233718 0.08725136981582722 11.25513616776495 0.029999999999999964 1.522878745280338 -0.360264960799351 SQQHTPVLSS(ph)S(ph)QPLRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQQHTPVLSSSQPLRK 16 1 Q15572-5;Q15572-4;Q15572-2;Q15572-6;Q15572 Q15572-5 TAF1C TATA box-binding protein-associated factor RNA polymerase I subunit C 2 S(0.001)QQHT(0.006)PVLS(0.102)S(0.945)S(0.945)QPLRK 43.592 0.043358 5949600.0 27501.0 27565.0 23495.0 32837.0 28603.0 28542.0 31304.0 34431.0 24325.0 24439.0 True False 32156.376130491015 30301.47102926143 24055.209905283693 30997.249348990375 22998.44747835352 27045.207274680637 28338.658498666366 33527.22273266005 24680.7071066212 28869.597240982454 1.113849142475834 1.0495979828304056 0.833236768233663 1.0736987111475031 0.7966320862178701 0.936805839337725 0.9816090699886044 1.1613332341563034 0.8549030629213343 1.0 14.817263360261881 -10.567912511450183 14.965150203427214 0.9999994592863196 0.977585447040248 0.003169348600243427 0.11707493412238365 0.0 0.0 0.11147559061286315 0.027036802045585142 2.7045031309330352e-11 10.567912511450183 -0.022414012246071646 SQQQPT(ph)PVTPK ddPTM_PC-9_AZD4547_30min_R2 4 SQQQPTPVTPK 11 0 O95251-2;O95251-4;O95251 O95251-2 KAT7 Histone acetyltransferase KAT7 1 SQQQPT(0.983)PVT(0.017)PK;S(0.003)QQQPT(0.928)PVT(0.069)PK;S(0.027)QQQPT(0.853)PVT(0.12)PK;SQQQPT(0.994)PVT(0.006)PK 143.55 0.00024207 365339800.0 360586.0 317345.0 342960.0 432419.0 400089.0 379959.0 409780.0 372676.0 337812.0 406328.0 True False 475244.8473452702 419920.56523029023 338412.12631391664 332731.48035695223 344543.5483888403 356200.10366495064 446249.6261509519 315087.48744252545 355668.0526631331 392102.58039661683 1.212042131588509 1.070945681626311 0.8630703882938194 0.8485827357228561 0.87870767909849 0.9084360100478034 1.1380940816547664 0.8035843251115827 0.9070790921686112 1.0 18.580871610586527 -5.001559469869165 3.1826656774226167 0.915556270396876 1.2061868902359556 0.5285477943605278 0.08883790051355246 0.20204034666369244 3.998754356969006 0.02366557128590888 0.11259849589828638 9.964156271822693e-06 5.001559469869165 0.29063061983907956 SQQQPT(ph)PVTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SQQQPTPVTPK 11 0 O95251-2;O95251-4;O95251 O95251-2 KAT7 Histone acetyltransferase KAT7 1 SQQQPT(0.572)PVT(0.428)PK;S(0.077)QQQPT(0.896)PVT(0.027)PK;S(0.003)QQQPT(0.884)PVT(0.113)PK;SQQQPT(0.68)PVT(0.32)PK 139.19 0.00026601 298428000.0 203027.0 219223.0 195567.0 256046.0 250799.0 230490.0 255630.0 242527.0 200206.0 175930.0 True False 237395.46113396587 240986.01064566587 200230.0589719772 241700.5727323324 201656.73632568555 218402.69864554456 231414.8757990703 236160.92322859715 203133.63399745952 207824.7163388859 1.1422869489058316 1.1595637655181787 0.9634564285677909 1.1630020576484628 0.9703212393508449 1.0508985769017476 1.1135098840780684 1.1363466645781692 0.9774276976094752 1.0 17.665007716836136 -5.213946514394333 24.961003195341988 1.0556773163856614 1.1509254734021275 0.26404557493111314 0.06823207204174797 553.9742970277717 291152.2977861197 0.016639306550852488 0.044023286437365236 6.110172702006881e-06 5.213946514394333 0.09524815701646605 SQQQPT(ph)PVTPK ddPTM_PC-9_Lapatinib_30min_R1 5 SQQQPTPVTPK 11 0 O95251-2;O95251-4;O95251 O95251-2 KAT7 Histone acetyltransferase KAT7 1 S(0.001)QQQPT(0.622)PVT(0.377)PK;S(0.005)QQQPT(0.68)PVT(0.315)PK;SQQQPT(0.73)PVT(0.27)PK;SQQQPT(1)PVTPK;S(0.001)QQQPT(0.994)PVT(0.005)PK 158.34 0.00024207 406841400.0 433743.0 388909.0 405607.0 449696.0 414244.0 385327.0 360291.0 357223.0 375885.0 324353.0 True False 427557.7452812758 388008.50510499865 372259.5581482973 482768.1439818803 389878.98235503887 368847.46245110827 378945.1050625981 373820.8846866757 333548.87305547285 380416.9838767937 1.123918656112761 1.0199557894362141 0.9785566205657675 1.269049922698076 1.0248727025324127 0.9695872636710866 0.9961308803850032 0.9826608709135491 0.8767980589518051 1.0 18.537222131802096 -6.519183322046658 21.79042181858611 0.9693766762424899 1.0916798363375597 0.39040130450377775 0.0780010127145119 33.72408778916877 198866.25120137943 0.02589371605363462 0.026554240654817096 3.025635993345401e-07 6.519183322046658 0.12230316009506981 SQQS(ph)TLVTREAQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQQSTLVTREAQPK 14 1 Q8IYY4 Q8IYY4 DZIP1L Zinc finger protein DZIP1L 1 SQQS(0.491)T(0.218)LVT(0.29)REAQPK 54.393 0.037092 4383700.0 5531.1 6135.6 56876.0 8856.8 20895.0 12776.0 6584.4 8466.2 10693.0 5437.0 True False 6467.4059857953835 6744.701819232229 58232.139543431185 8360.582210133021 16800.774746012547 12106.004069137402 5960.6779650721555 8243.971220680387 10849.364895831477 6422.685060731681 1.0069629640315274 1.050137404443098 9.066634747430275 1.3017269461412098 2.615849070466267 1.8848820944301867 0.9280663630100379 1.2835708341179697 1.689225735536144 1.0 12.6489608396369 -6.52108991552156 1.736699312454628 1.3102877656361502 3.386466383971965 0.1327197239522997 2.1866394482583433 0.7539372397180532 4.603841966212924 0.8700408514639356 0.9515038398482355 3.012382281595834e-07 6.52108991552156 2.0761786183358146 SQQSEVTR ddPTM_PC-9_AZD4547_30min_R2 1 SQQSEVTR 8 0 Q5T123;Q9H299 Q5T123 SH3BGRL3 SH3 domain-binding glutamic acid-rich-like protein 3 0 106.68 0.01761 4108200.0 5494.9 5169.5 5182.0 8313.3 6656.2 6682.9 4902.6 5379.1 6644.5 7783.6 False True 7242.163898979786 6840.439779917712 5113.283294141347 6396.797124204652 5732.101524375313 6265.017206547272 5338.92190240534 4547.883694421122 6995.7147049844 7511.098533143458 0.9641950331263833 0.9107109632144489 0.6807637087409364 0.8516460136926921 0.7631508891917546 0.8341013207192356 0.7108044021585956 0.6054884880491368 0.931383694956886 1.0 12.87480820870216 -5.076264179856515 6.396026403795805 0.7822415239195079 0.951912101276732 0.19918647879209428 0.1115238997810658 0.27495468984408283 18.61236955238568 0.026941675834538034 0.07450713692551891 8.389495011431983e-06 5.076264179856515 0.16967057735722413 SQQSEVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQQSEVTR 8 0 Q5T123;Q9H299 Q5T123 SH3BGRL3 SH3 domain-binding glutamic acid-rich-like protein 3 0 96.03399999999999 0.025332 0.0 3673.2 4425.3 5163.8 4364.8 5946.0 5334.4 2608.8 6233.9 5906.9 6104.6 False True 4295.000210993036 4864.614538211161 5286.924575820557 4120.254406872527 4780.923983718142 5054.654673325495 2361.6755779236137 6070.266730363024 5993.277237743098 7211.315656012989 0.595591763815213 0.674580724275315 0.7331428588085972 0.5713595969740901 0.6629752754938246 0.7009337705403019 0.327495798350525 0.8417696603395072 0.8310934541806865 1.0 12.816046778143166 -7.973057229890771 24.99769466895244 0.8891752892094997 0.6182319656691363 0.5675279444476258 0.11318744675107968 154.49548352144498 143341.92646169342 0.060884399171092916 0.02924682273472701 1.0640027982151762e-08 7.973057229890771 -0.27094332354036343 SQQSEVTR ddPTM_PC-9_Lapatinib_30min_R1 2 SQQSEVTR 8 0 Q5T123;Q9H299 Q5T123 SH3BGRL3 SH3 domain-binding glutamic acid-rich-like protein 3 0 ; 123.21 0.015182 10728600.0 10606.3 11343.8 11407.099999999999 9886.0 10544.9 9503.7 12532.8 13897.0 15951.699999999999 10656.2 False True 10455.052217042796 11317.534128060997 10469.252270679366 10613.049418729239 9924.669714071057 9097.248905206758 13181.687060538628 14542.70535349275 14155.051567152163 12498.109971506037 0.8365306627065108 0.9055396499041384 0.8376668387898502 0.8491723502934063 0.7940936458950939 0.7278899710393993 1.0546944370461655 1.1635923660976026 1.1325753733503485 1.0 13.609422319164779 -7.392522361913644 5.260288448832741 1.1103489525947463 0.829836763750302 0.8299958034877982 0.058275667573928935 0.08923395671870771 3.439837390116727 0.02580708465924783 0.017079829354499837 4.050210899790037e-08 7.392522361913644 -0.2805121888444443 SQQSSGRTS(ph)GSDDPGICSNTDSTQAQVLLGK ddPTM_PC-9_AZD4547_30min_R2 1 SQQSSGRTSGSDDPGICSNTDSTQAQVLLGK 31 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 S(0.003)QQS(0.114)S(0.086)GRT(0.086)S(0.353)GS(0.353)DDPGICS(0.003)NTDSTQAQVLLGK 71.295 1.8025e-05 14830000.0 54100.0 48301.0 91868.0 140620.0 108570.0 79267.0 62384.0 78802.0 58142.0 87508.0 True False 71302.67465009486 63913.35367246452 90649.77029451517 108202.23155734276 93496.92955461478 74310.42195923672 67936.05514617839 66624.96158981482 61215.26742075443 84444.3715553624 0.8443745075815771 0.7568693152102199 1.073485048498282 1.2813433218151729 1.1072014372600008 0.8799925985655327 0.8045066106228166 0.7889804893169814 0.7249182662295167 1.0 16.36571364627327 -6.944910710520987 5.654497919412707 0.815659012986485 1.0162032617733936 0.2547565385703875 0.14894527062697313 0.29164765544472954 19.71497171361031 0.060088465294652324 0.052492369654928865 1.135244194053549e-07 6.944910710520987 0.20054424878690857 SQQSSGRTS(ph)GSDDPGICSNTDSTQAQVLLGK ddPTM_PC-9_Lapatinib_30min_R1 1 SQQSSGRTSGSDDPGICSNTDSTQAQVLLGK 31 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 S(0.057)QQS(0.174)S(0.139)GRT(0.112)S(0.399)GS(0.119)DDPGICSNTDSTQAQVLLGK 71.556 1.6372000000000002e-05 7801800.0 17687.0 11413.0 12998.0 17747.0 20247.0 30689.0 23830.0 16492.0 35150.0 22146.0 True False 17434.78013660144 11386.573899712637 11929.354613730968 19052.173582256495 19056.111267133576 29376.503009553107 25063.80079891451 17258.27852700602 31191.036854090693 25973.906592309897 0.6712421204195506 0.438385110042856 0.45928226357997665 0.7335120542820955 0.7336636558466536 1.1310005641681418 0.9649607659070877 0.6644467772173972 1.2008604382725174 1.0 14.664775397704759 -6.253802406916682 1.7745725121316245 0.9647701308393419 0.5220394237935315 0.6147100035145113 0.15556247971713116 0.24254055221525037 1.5066743758229852 0.05428258589303384 0.07244475394918935 5.574393121337867e-07 6.253802406916682 -0.4427307070458104 SQQSSGRTSGS(ph)DDPGICSNTDSTQAQVLLGK ddPTM_PC-9_AZD4547_30min_R2 1 SQQSSGRTSGSDDPGICSNTDSTQAQVLLGK 31 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 S(0.007)QQS(0.025)S(0.019)GRT(0.147)S(0.147)GS(0.62)DDPGICS(0.033)NTDSTQAQVLLGK 88.413 2.3381e-09 14016000.0 15951.0 14435.0 19477.0 34555.0 24791.0 22065.0 18012.0 19838.0 14420.0 21625.0 True False 21023.08619858899 19100.8314581898 19218.72225395427 26588.878619428102 21349.197573809128 20685.272061899104 19615.033106132465 16772.492931889385 15182.211760986529 20867.915332137734 1.0074358585408043 0.9153205365355049 0.92096991712231 1.2741511644184107 1.023063264059261 0.9912476513666245 0.9399613135253735 0.8037454946953339 0.7275384972261743 1.0 14.348998864560578 -7.496800391346117 2.449881416947572 0.8251315748831465 1.0252013986191446 0.3283514128870818 0.11292686757647509 0.3376625021623655 4.025365865277626 0.0635223535416881 0.035037876438928785 3.1856613659477225e-08 7.496800391346117 0.20006982373599813 SQQSSGRTSGS(ph)DDPGICSNTDSTQAQVLLGK ddPTM_PC-9_Lapatinib_30min_R1 1 SQQSSGRTSGSDDPGICSNTDSTQAQVLLGK 31 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 SQQS(0.002)S(0.005)GRT(0.019)S(0.193)GS(0.777)DDPGICS(0.003)NT(0.001)DSTQAQVLLGK 90.964 1.2426e-09 8441700.0 16454.0 9644.6 13709.0 13302.0 17192.0 22261.0 23071.0 22371.0 37181.0 19100.0 True False 16219.362942705942 9622.268521262456 12581.898938270333 14280.273454171178 16180.800360772479 21308.948922925534 24265.503492730033 23410.43832935067 32993.28424671255 22401.409550849756 0.7240331420167572 0.4295385296813813 0.5616565738736321 0.6374720939660461 0.7223117065041423 0.9512325050151685 1.0832132432402928 1.0450430932129733 1.4728217959597554 1.0 14.451301892548466 -6.883062781945406 1.0864729726387503 1.1977929228707407 0.5554699364556553 0.7868610593458826 0.13449842331424094 0.20881562328920006 0.517916575998408 0.07414749711138588 0.05949061309818219 1.3089926803293148e-07 6.883062781945406 -0.6423229864150853 SQQTSFQSSPCNKS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 SQQTSFQSSPCNKSPK 16 1 Q12986-3;Q12986-2;Q12986 Q12986-3 NFX1 Transcriptional repressor NF-X1 1 SQQTSFQS(0.127)S(0.259)PCNKS(0.614)PK 88.176 0.0019167000000000001 6499400.0 24263.0 15306.0 21382.0 20011.0 21134.0 22133.0 18408.0 20321.0 17236.0 20873.0 True False 31978.129298248645 20253.365174856477 21098.46070924939 15397.773116868058 18199.90889939423 20749.02001114947 20046.2763389788 17180.856380125224 18147.059772008608 20142.242623246737 1.5876151378169665 1.005516890730007 1.04747326819006 0.7644517745554832 0.9035691427125 1.0301246191525086 0.995235571030349 0.8529763394020637 0.9009453471216045 1.0 14.297936700496688 -4.505515277738622 1.8800710258005073 0.9280103403331266 2.3071687047496234 0.8429925919320733 0.08348790492965176 0.7930957753516584 1.527094035763128 0.02313080847889888 2.4674374380569857 3.122372564553686e-05 4.505515277738622 1.3791583644164969 SQQTSFQSSPCNKS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 SQQTSFQSSPCNKSPK 16 1 Q12986-3;Q12986-2;Q12986 Q12986-3 NFX1 Transcriptional repressor NF-X1 1 SQQTSFQSSPCNKS(1)PK 118.19 6.1288e-05 5628800.0 22710.0 18096.0 16870.0 17455.0 21962.0 19466.0 14357.0 16815.0 17171.0 14521.0 True False 22386.151235496058 18054.099823814915 15483.013720083194 18738.698928173064 20670.2383389533 18633.484557462314 15100.335210659481 17596.286286175484 15237.021161353958 17030.93550198374 1.3144404917092518 1.0600768126749114 0.9091111711555572 1.1002741996169505 1.2136877822445902 1.094096361018566 0.8866415593494917 1.0331955214160664 0.8946673046574084 1.0 14.0558700633624 -7.180191695649922 7.302326933917915 0.9566941140560218 1.107896381380484 0.35727377994023635 0.10597592858370287 0.35365835835370624 27.8187274381395 0.04237024005026703 0.032747200974343256 6.604018852144311e-08 7.180191695649922 0.1512022673244623 SQRYS(ph)GAYGASVSDEELK ddPTM_PC-9_AZD4547_30min_R2 1 SQRYSGAYGASVSDEELK 18 1 A0A286YEX5;C9JRZ6;F8WAR4;Q9NX63 A0A286YEX5 CHCHD3 MICOS complex subunit MIC19 1 S(0.242)QRY(0.124)S(0.627)GAY(0.002)GAS(0.004)VS(0.001)DEELK 77.554 0.023551 7769200.0 40610.0 19944.0 39699.0 58214.0 50495.0 33400.0 38477.0 41443.0 29831.0 47168.0 True False 53523.135259525974 26390.507973823176 39172.5653211342 44793.66169733431 43484.64085714542 31311.492720028557 41901.378460174215 35038.93661539932 31407.805758806466 45516.662676821856 1.175902012842018 0.5797988345762844 0.8606203314875671 0.9841156856199892 0.9553565287924507 0.687912752794442 0.9205722914635254 0.7698046068136265 0.6900287479732131 1.0 15.474107161356836 -6.734871241794435 24.99917148442068 0.8059580935073271 0.8939952508660356 0.07515103953552771 0.1645179990296892 696.4904701812752 655357.9891661947 0.053040601639652726 0.053025587205213956 1.8413178284314305e-07 6.734871241794435 0.08803715735870854 SQS(ph)AAVTPSSTTSSTR ddPTM_PC-9_Lapatinib_30min_R1 1 SQSAAVTPSSTTSSTR 16 0 Q16186;A0A087WX59 Q16186 ADRM1 Proteasomal ubiquitin receptor ADRM1 1 S(0.114)QS(0.434)AAVT(0.02)PS(0.401)S(0.029)T(0.002)TSSTR 199.33 4.0389e-12 17423000.0 20598.0 18587.0 22908.0 21326.0 20314.0 19118.0 19626.0 14323.0 20734.0 16787.0 True False 20304.26874278941 18543.962943481878 21024.59266743721 22894.3851814505 19119.170458860626 18300.367706234687 20642.13824924448 14988.49886868222 18398.718581300604 19688.610582728536 1.0312697616459003 0.9418624471017382 1.0678555797066065 1.1628238105097253 0.9710776887238839 0.929490053619545 1.048430419328442 0.7612776333658912 0.9344853718342387 1.0 14.265073683976617 -6.942108984905551 1.4208007590997032 0.9088941101410287 1.0414033308398192 0.2473066273206178 0.08788490706387884 0.5575059193681808 2.3096124389679704 0.04541475455973208 0.0351309263989115 1.1425915688617422e-07 6.942108984905551 0.13250922069879045 SQS(ph)ADAPGPTER ddPTM_PC-9_AZD4547_30min_R2 1 SQSADAPGPTER 12 0 Q9NSC5-5;Q9NSC5-2;Q9NSC5;M0R1B8;M0R2U7 Q9NSC5-5 HOMER3 Homer protein homolog 3 1 SQS(1)ADAPGPTER 100.68 0.0029571 21937000.0 109720.0 94544.0 117610.0 205660.0 194810.0 185880.0 130430.0 202240.0 189530.0 148450.0 True False 144608.6776822254 125103.49909131245 116050.41455499128 158248.2644153258 167763.99416537242 174256.8942155363 142038.01732360953 170988.4550128699 199548.16886683603 143252.81068466348 1.0094648544142462 0.8733057207980208 0.8101091629570067 1.1046782514003946 1.171104380874344 1.216429146365029 0.99151993349905 1.1936132645191846 1.3929790830149449 1.0 17.128203920023147 -5.88729973297561 5.27664105874651 1.16257924279021 0.8967367752088846 0.5090223293007925 0.11577811166786463 0.16750734107949894 7.081449111736464 0.033196132302527444 0.0501382461163332 1.2962843177205444e-06 5.88729973297561 -0.26584246758132535 SQS(ph)ADAPGPTER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQSADAPGPTER 12 0 Q9NSC5-5;Q9NSC5-2;Q9NSC5;M0R1B8;M0R2U7 Q9NSC5-5 HOMER3 Homer protein homolog 3 1 S(0.002)QS(0.998)ADAPGPTER;S(0.02)QS(0.98)ADAPGPTER 88.10799999999999 0.0082145 32550000.0 151799.0 138870.0 169707.0 183465.0 225680.0 201343.0 170820.0 218620.0 185444.0 156588.0 True False 177495.57253308626 152656.09584014284 173753.45849738148 173186.0508515553 181459.62405743526 190784.21863590583 154638.69297029715 212881.456647037 188155.7676744195 184976.1648500744 0.9595591555103803 0.8252744128621793 0.9393289056360906 0.9362614420724145 0.9809892220682089 1.0313989307246094 0.8359925350146266 1.150858851569229 1.0171892569343852 1.0 17.496979858324536 -6.486993681941951 0.5786181235088984 1.0346058096363164 0.8851370189512832 0.24675430959056244 0.07799749741433779 1.2723403272065819 0.919116265750171 0.06034733025192514 0.09385605037726087 3.258414412652445e-07 6.486993681941951 -0.14946879068503327 SQS(ph)ADAPGPTER ddPTM_PC-9_Lapatinib_30min_R1 1 SQSADAPGPTER 12 0 Q9NSC5-5;Q9NSC5-2;Q9NSC5;M0R1B8;M0R2U7 Q9NSC5-5 HOMER3 Homer protein homolog 3 1 S(0.011)QS(0.983)ADAPGPT(0.006)ER 73.296 0.022994999999999998 21137000.0 96723.0 55085.0 78401.0 82549.0 91165.0 87996.0 86382.0 95104.0 100720.0 143280.0 True False 95343.71228317393 54957.454066912316 71955.1724166117 88619.92883539134 85802.85393728613 84232.61620869485 90854.43728962785 99522.87903422123 89375.85297138031 168045.75709140094 0.5673675666283915 0.3270386293479619 0.428187974882787 0.5273559438170791 0.5105922066846206 0.5012480985335458 0.5406529677521799 0.5922367857231303 0.531854267065894 1.0 17.35849459161132 -14.52287874526388 0.19577496847938858 3.2457890084895378 0.41511529747162745 0.85332860703249 0.0633852090595961 47.417219424603786 0.46576884506579036 41.47401378800992 0.15721086463793701 3.0000000001136885e-15 14.52287874526388 -2.8306737110179103 SQS(ph)CSDTAQER ddPTM_PC-9_AZD4547_30min_R2 2 SQSCSDTAQER 11 0 Q8NCN4 Q8NCN4 RNF169 E3 ubiquitin-protein ligase RNF169 1 S(0.017)QS(0.983)CSDTAQER;S(0.024)QS(0.975)CS(0.001)DTAQER 173.33 0.0010614 19975000.0 27372.0 31078.0 36360.0 56398.0 42124.0 40600.0 30850.0 52053.0 40093.0 38553.0 True False 36075.72662703139 41123.35573658629 35877.842642798045 43396.31244041403 36275.8097131675 38061.275581831134 33595.59023563104 44009.40490894435 42212.23412851826 37203.2712046199 0.9696923270164347 1.1053693507327815 0.9643733328036684 1.1664649649148346 0.9750704316738356 1.023062605771739 0.9030278560950613 1.1829444961140747 1.1346377015168587 1.0 15.183141859570808 -7.783300936056471 24.99998995895907 1.1190932795272355 1.021366227116015 0.19315030688702783 0.0828737412453106 367.85138703373605 420653.90814030275 0.04332240344034855 0.02083833715360381 1.6470207245070085e-08 7.783300936056471 -0.09772705241122037 SQS(ph)CSDTAQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQSCSDTAQER 11 0 Q8NCN4 Q8NCN4 RNF169 E3 ubiquitin-protein ligase RNF169 1 S(0.001)QS(0.999)CSDTAQER;S(0.001)QS(0.998)CSDTAQER 180.85 0.00096418 12401900.0 13269.0 13751.7 15047.4 13213.8 18881.1 14820.7 13669.7 16695.0 13745.2 11839.6 True False 15515.179625303997 15116.877894180821 15406.187083582285 12473.473625717605 15181.483994110424 14043.476401648768 12374.807055942367 16256.77393981468 13946.197546636377 13986.025757777967 1.1093344095034026 1.0808558596979532 1.1015414493294875 0.8918526135832979 1.085475191954915 1.004107717579374 0.8847979597821374 1.1623583583616595 0.997152285300244 1.0 13.771698446834458 SQS(ph)CSDTAQER ddPTM_PC-9_Lapatinib_30min_R1 2 SQSCSDTAQER 11 0 Q8NCN4 Q8NCN4 RNF169 E3 ubiquitin-protein ligase RNF169 1 S(0.078)QS(0.92)CS(0.002)DTAQER;S(0.001)QS(0.997)CS(0.001)DTAQER 163.62 0.00049266 13991800.0 3670.1 5924.2 6410.3 4562.1 5811.6 8376.8 8276.4 8249.6 7294.9 7211.6 True False 3617.763700986091 5910.4828788817595 5883.269878473577 4897.612052719468 5469.773114045216 8018.543791274547 8704.911495263785 8632.906532645447 6473.271543297474 8458.11545114702 0.42772692355428654 0.6987943015225961 0.6955769181036345 0.57904294177674 0.6466893418088129 0.9480295980338196 1.0291786090580375 1.0206654877801087 0.7653326063809666 1.0 13.046120537587386 -6.748274601913978 4.980968065839526 0.960917892475522 0.6145623876302042 0.7506755929990493 0.09896446590363146 0.09384979886579309 6.220031082321151 0.03407977253040553 0.03236185473685853 1.7853583460286372e-07 6.748274601913978 -0.34635550484531774 SQS(ph)DIFSR ddPTM_PC-9_Lapatinib_30min_R1 1 SQSDIFSR 8 0 Q96S53-3;Q96S53-2;Q96S53 Q96S53-3 TESK2 Dual specificity testis-specific protein kinase 2 1 S(0.003)QS(0.997)DIFSR 94.76700000000001 0.0066324 1611300.0 12352.0 9723.3 16266.0 8505.1 11924.0 13771.0 11621.0 11399.0 13766.0 10362.0 True False 12175.858214920616 9700.786296247772 14928.672268575769 9130.593426181871 11222.653763485981 13182.046431768915 12222.678518010303 11928.639154095414 12215.528117593532 12153.057893502892 1.00187609749065 0.7982177309822476 1.2283881471968252 0.7513000848175955 0.9234427961941735 1.0846691052805835 1.005728650773945 0.9815339693619453 1.0051402885296907 1.0 13.569031742988074 -6.727947662900646 24.97036464762138 1.0136550072842736 0.9381988836717411 0.08528919256722622 0.12223125256463421 500.64245147065327 373261.9506233827 0.03909176741177705 0.03908945117217823 1.8709075910236342e-07 6.727947662900646 -0.07545612361253251 SQS(ph)DLSSR ddPTM_PC-9_AZD4547_30min_R2 1 SQSDLSSR 8 0 Q1W6H9 Q1W6H9 FAM110C Protein FAM110C 1 S(0.36)QS(0.64)DLS(0.001)SR 76.165 0.025343 9154500.0 36153.0 37231.0 40262.0 51616.0 48603.0 47735.0 29231.0 41343.0 36183.0 37018.0 True False 47648.901970885054 49265.19265811325 39728.099573276515 39716.728659250504 41855.312398848204 44750.122903909054 31832.50237204963 34954.3893176279 38095.55951094145 35722.011087402294 1.3338807228490248 1.3791270748327797 1.1121462192056428 1.1118279024681503 1.1716952972339476 1.2527324621902547 0.8911173084338374 0.9785112386898872 1.0664449831150802 1.0 15.124525683528995 -3.207863397084909 0.2810139994363206 0.9723321241853152 2.2948072684437637 0.6068090953641523 0.09343556882704433 14.490440779611873 0.4667081303845442 0.1141867342369786 7.770043169265801 0.0006196359446164253 3.207863397084909 1.3224751442584486 SQS(ph)DLSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSDLSSR 8 0 Q1W6H9 Q1W6H9 FAM110C Protein FAM110C 1 S(0.094)QS(0.879)DLS(0.027)SR 72.34 0.032948000000000005 11837000.0 50305.0 51416.0 57947.0 57772.0 89644.0 65266.0 62177.0 55306.0 66560.0 46469.0 True False 58820.6429309607 56520.24068349379 59328.676245221286 54535.22213935113 72078.9017148384 61843.33606577343 56287.144437502495 53854.27610155077 67533.31408085128 54893.46185159838 1.0715418730554696 1.0296352020263053 1.080796769670189 0.993473909275102 1.3130689754947495 1.1266065935678036 1.0253888630611758 0.9810690432886707 1.2302615248319386 1.0 15.744346705173532 SQS(ph)DLSSR ddPTM_PC-9_Lapatinib_30min_R1 2 SQSDLSSR 8 0 Q1W6H9 Q1W6H9 FAM110C Protein FAM110C 1 S(0.015)QS(0.794)DLS(0.16)S(0.031)R;S(0.067)QS(0.778)DLS(0.155)SR 122.18 0.0033399000000000002 29990000.0 203155.0 158560.0 177011.0 165042.0 172712.0 156883.0 172369.0 169374.0 194057.0 132481.0 True False 200257.97244593565 158192.86406189707 162457.83886221927 177179.73924397238 162553.41972485647 150173.47980213494 181293.4234120057 177243.73437018658 172200.25714919713 155380.16433016345 1.2888258505146928 1.0181020514675025 1.045550695370721 1.1402983129010442 1.0461658373552158 0.9664906743375239 1.1667732763287586 1.1407101745211556 1.1082512230022687 1.0 17.245442816991797 -4.75194327586657 24.994574573798356 1.0750942408360789 1.2888262742342056 0.513998498845458 0.06360277593780898 334.06411067812 879223.9287613025 0.01638770715948394 0.203942336265367 1.7703401711429386e-05 4.75194327586657 0.21373203339812674 SQS(ph)DLSSSSSR ddPTM_PC-9_AZD4547_30min_R2 4 SQSDLSSSSSR 11 0 J3KP75 J3KP75 PHACTR2 Phosphatase and actin regulator 1 S(0.086)QS(0.848)DLS(0.054)S(0.009)S(0.003)SSR;SQS(0.891)DLS(0.019)S(0.032)S(0.056)SS(0.001)R;S(0.001)QS(0.999)DLS(0.001)SSSSR;SQS(0.998)DLS(0.002)SSSSR 162.67 0.00027304 38434700.0 75984.0 78382.0 135180.0 185806.0 167798.0 146354.0 116455.0 161004.0 129487.0 149847.0 True False 100145.33143461763 103717.44865644854 133387.42487495704 142971.29737408346 144502.14410431276 137202.46124392396 126819.26939677169 136124.53130385696 136331.41846705007 144600.90213987697 0.6925636697462919 0.7172669542277088 0.9224522316321873 0.9887303278079335 0.9993170302943983 0.9488354444096326 0.8770295863997822 0.9413809270164819 0.9428116730224299 1.0 17.14171702747734 -5.272142780280455 3.772158953088436 0.9528159154169297 0.6965679534190087 0.8942437999818836 0.03426640274728696 0.06710158419821709 2.1545418778493595 0.009968900489998793 0.026036434819402043 5.343886429022353e-06 5.272142780280455 -0.256247961997921 SQS(ph)DLSSSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SQSDLSSSSSR 11 0 J3KP75 J3KP75 PHACTR2 Phosphatase and actin regulator 1 S(0.228)QS(0.692)DLS(0.076)S(0.001)SS(0.001)S(0.002)R;S(0.001)QS(0.998)DLSSSSSR;SQS(0.999)DLS(0.001)SSSSR;SQS(0.999)DLS(0.001)SSSSR 143.94 0.00010001 29435200.0 68417.3 73420.0 159789.0 106845.0 169052.0 176086.0 137785.0 152829.0 165667.0 106775.3 True False 79998.99758672933 80708.65238412384 163598.9757631571 100858.82104616378 135927.474149936 166851.7401783129 124733.00732298603 148817.40068571086 168089.5664638278 126132.81665719056 0.6342441222426214 0.6398703725413303 1.2970373618769946 0.7996239497313568 1.077653522313434 1.3228257689019192 0.9889021004104824 1.1798468045803931 1.332639442443192 1.0 16.944584152712977 -4.522417703329522 0.7349714762934051 1.154125652661488 1.7073464578652357e-08 0.4960115030000397 0.17928611092416943 3.2160091410387164 1.0162131346381509 0.07066940042248426 3.3480058785731748 3.0031864560225807e-05 4.522417703329522 -1.1541256355880234 SQS(ph)DLSSSSSR ddPTM_PC-9_Lapatinib_30min_R1 4 SQSDLSSSSSR 11 0 J3KP75 J3KP75 PHACTR2 Phosphatase and actin regulator 1 S(0.143)QS(0.856)DLS(0.001)SSSSR;SQS(0.96)DLS(0.032)S(0.006)S(0.001)SSR;S(0.002)QS(0.998)DLSSSSSR;SQS(0.975)DLS(0.025)S(0.001)SSSR 198.37 8.262100000000001e-05 34994200.0 66601.0 66681.0 84941.0 69232.0 87689.0 83381.0 73499.0 84912.0 104327.0 71658.0 True False 65651.25752687229 66526.60424136854 77957.47886174177 74323.55223118172 82531.30542320707 79814.98900060437 77304.418586631 88857.32150649608 92576.59464798645 84043.98982171703 0.7811535086106532 0.7915688484386781 0.9275794619831041 0.8843410741070798 0.9820012781197225 0.9496811035496571 0.9198090041966984 1.0572715752189967 1.101525461182527 1.0 16.358857032271658 -4.611562655279678 0.3366173176294564 1.049357344015078 0.5161434804024522 0.7627924236304873 0.04777514335869822 3.8246912642010185 0.3199198203099224 0.04981764628494669 0.8547686418676612 2.445892383871496e-05 4.611562655279678 -0.5332138636126259 SQS(ph)ESSDEVTELDLSHGK ddPTM_PC-9_AZD4547_30min_R2 1 SQSESSDEVTELDLSHGK 18 0 Q86YS7-3;Q86YS7;Q86YS7-2;Q86YS7-4;Q86YS7-5 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 S(0.052)QS(0.855)ES(0.086)S(0.006)DEVTELDLSHGK 132.39 2.277e-05 7605700.0 23807.0 33194.0 40934.0 36001.0 40593.0 45737.0 38261.0 56180.0 43098.0 36677.0 True False 31377.130783637862 43923.31135595099 40391.188414199525 27701.52565990541 34957.36263618388 42877.05815975887 41666.154878621695 47498.67188796983 45376.07229368917 35392.949393609946 0.8865361977801962 1.2410186805138417 1.1412213196759462 0.7826848605306346 0.9876928381248524 1.2114576178130028 1.1772444962200395 1.3420376855212164 1.2820653003245226 1.0 15.111174370140965 -6.768843621968371 22.342268505380343 1.2223563049883517 1.0156881217346156 0.30812718017473617 0.14414295187627438 57.3907446361384 173172.83217303304 0.05198653564874422 0.046899273812706546 1.7027715213070553e-07 6.768843621968371 -0.20666818325373604 SQS(ph)ESSDEVTELDLSHGK ddPTM_PC-9_Lapatinib_30min_R1 1 SQSESSDEVTELDLSHGK 18 0 Q86YS7-3;Q86YS7;Q86YS7-2;Q86YS7-4;Q86YS7-5 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 S(0.205)QS(0.68)ES(0.056)S(0.056)DEVT(0.004)ELDLSHGK 129.08 2.3886999999999997e-05 7134100.0 17016.0 25630.0 26941.0 25776.0 33635.0 27217.0 28983.0 31156.0 28116.0 26735.0 True False 16773.348719647773 25570.655309702503 24726.0149752674 27671.65302621533 31656.65542895429 26052.992355925802 30483.59792509185 32603.621500569923 24949.280005394427 31356.109127851763 0.5349308057085759 0.815491973364438 0.7885549471220826 0.8824963873351317 1.0095849360606917 0.830874527502664 0.9721741240533918 1.0397853052376982 0.7956752511501329 1.0 14.936458931023974 -4.276481301973033 0.7739922090423642 0.9408138912180444 1.360716551361175e-13 0.6830973118535649 0.08053105452457884 3.0093681150803966 0.7962097424290786 0.029422986440858397 2.9339611434501762 5.290767754839372e-05 4.276481301973033 -0.9408138912179083 SQS(ph)ESSDEVTELDLSHGKK ddPTM_PC-9_AZD4547_30min_R2 2 SQSESSDEVTELDLSHGKK 19 1 Q86YS7-3;Q86YS7;Q86YS7-2;Q86YS7-4;Q86YS7-5 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 S(0.114)QS(0.505)ES(0.345)S(0.036)DEVTELDLSHGKK;S(0.225)QS(0.747)ES(0.016)S(0.005)DEVT(0.007)ELDLSHGKK 78.352 0.001147 23279300.0 68361.7 58096.6 85305.0 108930.0 104353.0 99481.0 85021.0 107238.0 73306.5 93738.0 True False 90099.29858830674 76875.18980906601 84173.79996270324 83817.8714517234 89865.3872138964 93260.43734374715 92587.7042924986 90666.83118408872 77181.3319318142 90456.26115162676 0.9960537550549247 0.849860350520175 0.9305469725485052 0.9266121591210165 0.9934678492101292 1.0310003548280633 1.023563246078666 1.0023278657528083 0.853244772105266 1.0 16.464932745522297 -6.228879585108514 5.643361341354879 0.9884572528453792 0.9201108178842002 0.19516287624652462 0.05702098540385818 0.29021824755504777 27.63209107508423 0.01723399769988324 0.02187882232028816 5.90364745277869e-07 6.228879585108514 -0.06834643496117898 SQS(ph)ESSDEVTELDLSHGKK ddPTM_PC-9_Lapatinib_30min_R1 1 SQSESSDEVTELDLSHGKK 19 1 Q86YS7-3;Q86YS7;Q86YS7-2;Q86YS7-4;Q86YS7-5 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 S(0.169)QS(0.492)ES(0.169)S(0.169)DEVTELDLSHGKK 90.545 0.00045421 11003000.0 17962.0 16105.0 15394.0 13985.0 14254.0 16383.0 16538.0 15677.0 17166.0 11431.0 True False 17705.858586172628 16067.709861988258 14128.364742558426 15013.503552592385 13415.60774444223 15682.337280638294 17394.256718944514 16405.410651702226 15232.584314006295 13406.833119149927 1.320659280891779 1.1984716837444342 1.0538181997937965 1.1198396682619653 1.0006544890366218 1.1697271936829066 1.297417262104879 1.2236603906308954 1.136180645990776 1.0 13.710680872357292 -4.86368879671221 3.54519605884481 1.1356929683304435 1.327464930283686 0.30736197491709805 0.08891239951741915 0.35397521636874324 7.470670713844865 0.024296959347573366 0.1577041629776131 1.3687092530776196e-05 4.86368879671221 0.19177196195324253 SQS(ph)FAGVLGSHER ddPTM_PC-9_AZD4547_30min_R2 4 SQSFAGVLGSHER 13 0 H3BSV5;A0A0A0MTL6;Q6ZS17-2;Q6ZS17;Q6ZS17-3;Q6ZS17-4;H3BS40;H3BUP6;H3BQI5;H3BU12;H3BMG9;H3BV02 H3BSV5 FAM65A Protein FAM65A 1 S(0.257)QS(0.743)FAGVLGSHER;S(0.253)QS(0.747)FAGVLGSHER;S(0.033)QS(0.967)FAGVLGSHER;S(0.255)QS(0.745)FAGVLGSHER 131.9 3.5526e-05 64586000.0 210773.0 182728.0 288060.0 377657.0 317054.0 278516.0 217725.0 291168.0 230009.0 294173.0 True False 277794.4296492509 241791.2525592041 284240.1361849395 290594.01339248643 273036.524850409 261100.35049136096 237102.10321078714 246174.67597501623 242166.80616731994 283874.0928092924 0.9785832405490915 0.8517552629279218 1.001289456787073 1.0236721869075547 0.9618226240667757 0.9197752000101296 0.8352368504796004 0.86719669815166 0.8530782213014714 1.0 18.11489166488328 -6.965001135732151 3.9911830830346124 0.8774056895901365 0.9621243654170971 0.25053044338033015 0.05947179529175912 0.27998720965879914 9.763655714089477 0.02247226486309559 0.019006888978486944 1.0839240794260451e-07 6.965001135732151 0.08471867582696058 SQS(ph)FAGVLGSHER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SQSFAGVLGSHER 13 0 H3BSV5;A0A0A0MTL6;Q6ZS17-2;Q6ZS17;Q6ZS17-3;Q6ZS17-4;H3BS40;H3BUP6;H3BQI5;H3BU12;H3BMG9;H3BV02 H3BSV5 FAM65A Protein FAM65A 1 S(0.004)QS(0.996)FAGVLGSHER;S(0.235)QS(0.765)FAGVLGSHER;S(0.171)QS(0.829)FAGVLGSHER 101.28 0.0011576 40916000.0 95323.0 99321.0 121666.0 137008.0 132640.0 117671.0 111523.0 97258.0 104534.0 86272.0 True False 111459.30118493145 109180.93249037824 124566.9788608744 129331.88594592926 106650.14416420691 111500.12561204344 100958.73408340043 94705.08055336926 106062.6119911012 101912.43067122353 1.0936771937518277 1.0713210525083383 1.2222942583200276 1.269049173826133 1.0464880825801082 1.0940777771433052 0.990641999395542 0.9292789891244408 1.0407230137927574 1.0 16.636970508020653 -6.896890737878424 1.669624756017486 0.9851124312046473 1.1559709232783484 0.54399688176342 0.06617573330684795 0.2961951100117764 1.6942435310753619 0.03223114839175512 0.026399446943088344 1.267970828595337e-07 6.896890737878424 0.17085849207370107 SQS(ph)FAGVLGSHER ddPTM_PC-9_Lapatinib_30min_R1 3 SQSFAGVLGSHER 13 0 H3BSV5;A0A0A0MTL6;Q6ZS17-2;Q6ZS17;Q6ZS17-3;Q6ZS17-4;H3BS40;H3BUP6;H3BQI5;H3BU12;H3BMG9;H3BV02 H3BSV5 FAM65A Protein FAM65A 1 S(0.283)QS(0.717)FAGVLGSHER;S(0.225)QS(0.775)FAGVLGSHER;S(0.266)QS(0.734)FAGVLGSHER 97.77600000000001 0.0016582 40468000.0 221690.0 183975.0 233667.0 181904.0 183321.0 205458.0 154476.0 171916.0 224246.0 143910.0 True False 218528.6599470332 183549.01719089027 214455.8012407042 195281.82697395553 172538.41920295305 196671.04028599084 162474.0114231269 179903.84497021412 198989.05406493373 168784.65175197844 1.2947187891713718 1.087474573580348 1.2705882852182406 1.156988061099972 1.0222399810172942 1.1652187461629522 0.9626112904026088 1.0658779877365558 1.1789523040124485 1.0 17.364824194548 -6.0563594998569705 5.388106413457167 1.0697170556561417 1.206314174300027 0.41667389808600686 0.08111844185647966 0.21501444871449704 13.422880784907626 0.02303860503810658 0.030649153650960517 8.782951815187182e-07 6.0563594998569705 0.13659711864388524 SQS(ph)FALR ddPTM_PC-9_AZD4547_30min_R2 1 SQSFALR 7 0 Q8WXE0-2;Q8WXE0 Q8WXE0-2 CASKIN2 Caskin-2 1 S(0.025)QS(0.975)FALR 90.149 0.016122 13537000.0 55796.0 50818.0 57790.0 81213.0 76003.0 62143.0 45696.0 88349.0 73266.0 63122.0 True False 73537.96737110344 67243.92469984676 57023.6668406848 62490.59757834219 65451.2953572755 58257.18838624955 49762.85547511815 74696.69210805003 77138.69118449646 60912.1179928415 1.2072797629487413 1.1039498693470056 0.9361629298030044 1.0259140485918778 1.0745201039465981 0.9564137696393358 0.8169615031440274 1.2263026565063542 1.2663931862221889 1.0 15.894441649209005 -10.29738338537228 0.0016638844552767968 0.548479994794528 1.5548588346326453 0.0 0.13569058955410113 9972395.675846685 3397.3704621900483 1036811.4990719734 1018084.3576808485 5.042159905360604e-11 10.29738338537228 1.0063788398381173 SQS(ph)FALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSFALR 7 0 Q8WXE0-2;Q8WXE0 Q8WXE0-2 CASKIN2 Caskin-2 1 S(0.181)QS(0.819)FALR 84.81700000000001 0.019701 7978300.0 37017.0 27801.0 31817.0 32310.0 41390.0 32806.0 31770.0 38159.0 30964.0 29560.0 True False 43283.246980923795 30560.8995495918 32575.63794664443 30499.775450433313 33279.926620601065 31085.595608337608 28760.51560511852 37157.366682802545 31416.78992186718 34918.99400316874 1.2395330454536015 0.8751941578505538 0.9328916504206376 0.873443703666423 0.953060864742583 0.8902202510621221 0.8236352857848264 1.064101866148569 0.8997048975413282 1.0 15.09172437587231 -4.756399088763096 24.996462160614428 0.9210659807998997 1.2395335367039197 0.6755262181722188 0.06567037948118028 89.22379924634865 442440.3736167758 0.015755930692901904 0.12809698938275113 1.7522695384946947e-05 4.756399088763096 0.3184675559040201 SQS(ph)FNNYDK ddPTM_PC-9_AZD4547_30min_R2 1 SQSFNNYDK 9 0 Q8IVL1-4;Q8IVL1-11;A0A0A0MTL4;A0A0A0MTE8;Q8IVL1-8;Q8IVL1-9;Q8IVL1-10;Q8IVL1-13;Q8IVL1-12;Q8IVL1-3;Q8IVL1-2;Q8IVL1 Q8IVL1-4 NAV2 Neuron navigator 2 1 SQS(1)FNNYDK 100.09 0.0039328 5124100.0 14495.0 14699.0 14110.0 21395.0 15460.0 16422.0 10375.0 12635.0 13637.0 16681.0 True False 19104.10848527034 19450.164295388437 13922.892180689776 16462.7132994549 13313.645859025019 15395.129743961346 11298.35490096182 10682.551073415783 14357.823979512728 16097.003267301234 1.1868114932968679 1.2083096444975365 0.8649369046828825 1.0227191375985214 0.827088473422242 0.9563972553347465 0.7018918188277203 0.6636360132395489 0.8919563313178049 1.0 13.97450451050964 -5.1196328947859016 0.7054649973673072 0.8099292836129509 1.3777901179207288 0.5474639994802963 0.11589336675769187 1.457708011248534 0.7484481189499256 0.052172624573843036 0.6138059651213785 7.592190649058713e-06 5.1196328947859016 0.5678608343077779 SQS(ph)FNNYDK ddPTM_PC-9_Lapatinib_30min_R1 2 SQSFNNYDK 9 0 Q8IVL1-4;Q8IVL1-11;A0A0A0MTL4;A0A0A0MTE8;Q8IVL1-8;Q8IVL1-9;Q8IVL1-10;Q8IVL1-13;Q8IVL1-12;Q8IVL1-3;Q8IVL1-2;Q8IVL1 Q8IVL1-4 NAV2 Neuron navigator 2 1 S(0.003)QS(0.996)FNNY(0.001)DK;S(0.033)QS(0.967)FNNYDK 100.93 0.0036611999999999994 4905300.0 42004.0 42313.0 36737.0 39518.0 40780.0 41793.0 36542.0 28393.0 45578.0 30393.0 True False 41405.01525740981 42215.02684820295 33716.625668920955 42424.28554818349 38381.40057656478 40005.6108142414 38433.96595862079 29712.242433742522 40444.52568238251 35646.38955387313 1.1615486386028955 1.1842721626660815 0.9458636930947611 1.1901425664460852 1.076726172185213 1.1222906811861013 1.0782008062986221 0.8335274008280079 1.1346037056924898 1.0 15.121468340187782 -7.542181597415472 24.995525128784564 0.9816121081234094 1.110001182678165 0.2568707844094279 0.09405793836040552 309.0004738179672 400124.24027524714 0.041749200719401074 0.024108399888499627 2.8695804347136325e-08 7.542181597415472 0.12838907455475568 SQS(ph)FNSIDK ddPTM_PC-9_AZD4547_30min_R2 3 SQSFNSIDK 9 0 Q8IVL0-3;Q8IVL0-2;Q8IVL0;F8VZV4;H0YHX7;A0A1B0GTC4 Q8IVL0-3 NAV3 Neuron navigator 3 1 SQS(0.993)FNS(0.007)IDK;S(0.005)QS(0.975)FNS(0.02)IDK;SQS(0.998)FNS(0.001)IDK 120.03 0.0017015 50889000.0 230396.0 186939.0 256530.0 265865.0 262284.0 262441.0 249728.0 258421.0 256325.0 240125.0 True False 303657.1354654952 247363.3759586105 253128.24458627566 204573.93182330354 225870.39395139192 246030.52278254478 271953.3082127604 218487.97237381712 269873.8162021411 231718.2968383622 1.3104581710149317 1.0675176683659198 1.0923964487916473 0.8828561862165182 0.9747628781725012 1.0617656272269524 1.173637610509733 0.9429034105417491 1.164663386035479 1.0 17.822012440589383 -4.608961817069617 2.1311764642395516 1.03293302183852 1.494431176090566 0.46364567890830055 0.0876266788085722 1.1920014747231356 3.987146771076656 0.02337482551211287 1.2519320006350623 2.460583927814483e-05 4.608961817069617 0.461498154252046 SQS(ph)FNSIDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSFNSIDK 9 0 Q8IVL0-3;Q8IVL0-2;Q8IVL0;F8VZV4;H0YHX7;A0A1B0GTC4 Q8IVL0-3 NAV3 Neuron navigator 3 1 S(0.023)QS(0.955)FNS(0.022)IDK 83.617 0.014057 14000000.0 63078.0 66386.0 57017.0 64850.0 55096.0 52839.0 75612.0 58474.0 56397.0 36699.0 True False 73755.85955271122 72976.36335021025 58376.50151817664 61216.66474653675 44300.33430994533 50068.02982225664 68449.4839765256 56939.11945832426 57221.69943235833 43352.23819087584 1.7013160711096642 1.6833355414985072 1.3465625756425859 1.4120762226163621 1.0218696002475145 1.1549122239505099 1.5789146496923399 1.3134066852010422 1.3199249178419936 1.0 15.403818858429583 -5.320121873859618 1.935043933371335 1.2676140081321856 1.7312879488950788 0.5228666664278455 0.16363167200096576 0.3237457056199678 2.2085586830433903 0.04842392756439728 0.17768044099337452 4.784957956297259e-06 5.320121873859618 0.46367394076289314 SQS(ph)FNSIDK ddPTM_PC-9_Lapatinib_30min_R1 2 SQSFNSIDK 9 0 Q8IVL0-3;Q8IVL0-2;Q8IVL0;F8VZV4;H0YHX7;A0A1B0GTC4 Q8IVL0-3 NAV3 Neuron navigator 3 1 S(0.006)QS(0.994)FNSIDK;S(0.007)QS(0.964)FNS(0.029)IDK 95.631 0.005364 25142000.0 59982.0 78942.0 102491.0 102048.0 119736.0 88957.0 80435.0 92898.0 99138.0 76231.0 True False 59126.6456806484 78759.21464918199 94064.58560670094 109552.95034214879 112693.36389003342 85152.51647889522 84599.5307285223 97214.38022082245 87972.03447057879 89407.42677857733 0.6613169376530539 0.8809023756408262 1.0520891719617134 1.2253227085202107 1.2604474589021006 0.9524098785415261 0.9462248694175925 1.0873188472539255 0.983945491334256 1.0 16.448107055830512 -4.946149433038934 2.283323511406406 1.0713850508052813 0.6299218481972914 0.6084806733529033 0.10147317280237429 0.3089466289430762 2.507487558289844 0.030151425989161013 0.24148252238124565 1.132010791354049e-05 4.946149433038934 -0.44146320260799 SQS(ph)FSHQQPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQSFSHQQPSR 11 0 B3KNS5;Q8WVR3-2;Q8WVR3-3;Q8WVR3 B3KNS5 C7orf43 Uncharacterized protein C7orf43 1 S(0.487)QS(0.513)FSHQQPSR;S(0.099)QS(0.898)FS(0.002)HQQPSR 136.14 7.848e-05 8607300.0 31690.0 30505.0 35786.0 44314.0 49046.0 45846.0 39727.0 35602.0 38159.0 29777.0 True False 37054.49109396968 33533.334799478354 36639.27395916077 41831.23024792644 39435.78837965694 43441.755052729575 35963.77096142723 34667.4852234371 38717.003185264504 35175.33438539768 1.0534225684390963 0.9533195742241198 1.0416183555705107 1.189220542713357 1.1211204973229167 1.2350061715621823 1.0224144728061735 0.9855623501287482 1.100686144474495 1.0 15.102276517691058 -5.529073990866339 24.97815187692437 1.0983451186263873 1.001895530840442 0.18048683680741318 0.07786566748993491 237.34070582187474 956912.4688633287 0.02226762273638586 0.03869234015927409 2.957508552108472e-06 5.529073990866339 -0.09644958778594526 SQS(ph)FSHQQPSR ddPTM_PC-9_Lapatinib_30min_R1 2 SQSFSHQQPSR 11 0 B3KNS5;Q8WVR3-2;Q8WVR3-3;Q8WVR3 B3KNS5 C7orf43 Uncharacterized protein C7orf43 1 S(0.105)QS(0.893)FS(0.001)HQQPSR;S(0.398)QS(0.598)FS(0.004)HQQPSR 95.195 0.0035814 35507000.0 88673.0 65402.0 98944.0 57707.0 80032.0 75393.0 59246.0 70646.0 83989.0 50514.0 True False 87408.50675936337 65250.56568728687 90809.20625488514 61950.9652849088 75324.67510896597 72168.61713966687 62313.46798709561 73928.47106590257 74529.2743766209 59245.27759432589 1.4753666504507148 1.101363152251246 1.532766997509726 1.0456692550098212 1.2714038682499151 1.2181328212154192 1.0517879317534595 1.2478373647283398 1.2579783132581492 1.0 15.854412541783644 -1.522878745378737 0.06338922303058248 0.7708845217339535 2.191820012510952 0.26582948648023885 0.14567727289752969 445.38267090747263 2.109372142249523 9.121464846297323 57.67825302477391 0.029999999993202815 1.522878745378737 1.4209354907769987 SQS(ph)FTHSPSGDPK ddPTM_PC-9_AZD4547_30min_R2 1 SQSFTHSPSGDPK 13 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 S(0.269)QS(0.599)FT(0.12)HS(0.005)PS(0.008)GDPK 90.259 0.0056992 10545000.0 15616.0 11935.0 26210.0 36926.0 31972.0 23432.0 18344.0 24923.0 18525.0 26167.0 True False 20581.56316702185 15792.755348354365 25862.43827469024 28413.28120101296 27533.23967689184 21966.793335799666 19976.58046296323 21071.723023564824 19504.19368046295 25250.901294614923 0.8150823183254504 0.6254333326201854 1.024218421867014 1.1252382982096745 1.0903864125738614 0.8699409608988636 0.7911234624810596 0.8344938969785858 0.7724157428242955 1.0 14.62404726325804 -10.56323694841471 14.769038505462136 1.0000136463658407 0.888406862528418 0.05279171053731346 0.14697850549210875 0.0 0.0 0.15944068459097657 0.03867004609349334 2.7337767874422855e-11 10.56323694841471 -0.11160678383742262 SQS(ph)FTHSPSGDPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQSFTHSPSGDPK 13 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 S(0.142)QS(0.666)FT(0.072)HS(0.114)PS(0.005)GDPK;S(0.043)QS(0.953)FT(0.002)HS(0.002)PSGDPK 108.66 0.0008727 12013600.0 18459.6 21283.3 28396.0 31295.0 44110.0 42743.0 45330.0 43677.0 44008.0 38523.0 True False 21584.445686280927 23396.165367570477 29073.06833242968 29541.642609758936 35466.96214628444 40501.48183524888 41036.014239220116 42530.5250296068 44651.53374504365 45506.91495209977 0.4743113372769952 0.5141233017486926 0.6388714410333413 0.6491682119267862 0.779375226459906 0.8900071973211199 0.9017533770947627 0.9345947769558561 0.9812032697018357 1.0 15.47379816462134 -6.050784789419741 0.5315059286380815 0.9985368688957429 0.3954852788079526 0.9865400987810795 0.021415851068351345 0.14278995084212143 0.0735434629636208 0.01665332411547215 0.046229322652294735 8.896418623735743e-07 6.050784789419741 -0.6030515900877903 down SQS(ph)GEDESMNQPGPIK ddPTM_PC-9_Lapatinib_30min_R1 2 SQSGEDESMNQPGPIK 16 0 A0A0C4DG33;O43933-2;O43933 A0A0C4DG33 PEX1 Peroxisome biogenesis factor 1 1 S(0.01)QS(0.97)GEDES(0.019)MNQPGPIK;S(0.021)QS(0.73)GEDES(0.249)MNQPGPIK 229.02 6.212399999999999e-29 9968500.0 39245.0 43682.0 52944.0 51587.0 54333.0 54687.0 51953.0 52334.0 58945.0 43481.0 True False 38685.35910334841 43580.85701281409 48591.14868975011 55380.880069187246 51137.23976278795 52348.16449162345 54642.87213201867 54765.62869465997 52305.993381632354 50996.63291520934 0.7585865358536409 0.8545830287516188 0.9528305284496182 1.0859713064050223 1.0027571790438086 1.026502368865436 1.0714996070989986 1.073906757446462 1.0256754297602364 1.0 15.638114374929822 -5.2058113623756395 1.6437474940306078 1.043818924165887 0.7500258484780068 0.9018660005499372 0.031138614712497924 0.13675611309067998 0.5970700618645546 0.008980801810711732 0.0489983730900892 6.225706426115693e-06 5.2058113623756395 -0.29379307568788027 SQS(ph)GGYSDR ddPTM_PC-9_AZD4547_30min_R2 2 SQSGGYSDR 9 0 F6WMK9;K7EMY9;K7EPM4;K7EQR7;D6W5Y5;Q14011;Q14011-3;Q14011-2 F6WMK9 CIRBP Cold-inducible RNA-binding protein 1 S(0.003)QS(0.997)GGYSDR;S(0.108)QS(0.89)GGYS(0.002)DR 96.64 0.0050398000000000005 25510000.0 43239.0 34078.0 51281.0 73255.0 58236.0 50145.0 47118.0 47957.0 50994.0 59643.0 True False 56988.102572928874 45093.04706838877 50600.980433589815 56367.19152846784 50150.93662653174 47009.425222929116 51311.41072033917 40546.347592227976 53689.43873368565 57554.91672391632 0.9901517683761687 0.7834786258955847 0.8791773720447957 0.9793636189042572 0.8713579913094038 0.8167751410088455 0.8915208924108697 0.7044810400251935 0.9328384400454808 1.0 15.812651557780509 -6.516369258011368 24.745208397407065 0.8511656404390445 0.9006182341822243 0.02086133010690494 0.09030405602848443 816.8940172962148 3105359.614597786 0.02819477134411527 0.029219060804173448 3.0453046244143347e-07 6.516369258011368 0.049452593743179785 SQS(ph)GGYSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSGGYSDR 9 0 F6WMK9;K7EMY9;K7EPM4;K7EQR7;D6W5Y5;Q14011;Q14011-3;Q14011-2 F6WMK9 CIRBP Cold-inducible RNA-binding protein 1 S(0.003)QS(0.978)GGYS(0.019)DR 82.505 0.015677 13589000.0 11974.0 12675.0 17805.0 13122.0 23221.0 20934.0 14606.0 15122.0 15313.0 15642.0 True False 14000.96170271987 13933.290233843232 18229.538725838527 12386.816882097986 18671.011743343253 19836.184187799172 13222.413941717383 14725.063523083414 15536.923655650182 18477.77077799613 0.7577192005971101 0.7540568827942925 0.9865659091055937 0.6703631639834264 1.010458023733969 1.0735160873096596 0.7155849101377001 0.796906926706681 0.8408440521489748 1.0 14.17350309509551 -6.26814468046752 24.93923408202158 0.894896886728459 0.803338447705264 0.16040230970415226 0.12519860909490801 1297.5836529835556 4826136.865047614 0.0405648404573515 0.0469970443884353 5.393309203730724e-07 6.26814468046752 -0.09155843902319505 SQS(ph)GGYSDR ddPTM_PC-9_Lapatinib_30min_R1 2 SQSGGYSDR 9 0 F6WMK9;K7EMY9;K7EPM4;K7EQR7;D6W5Y5;Q14011;Q14011-3;Q14011-2 F6WMK9 CIRBP Cold-inducible RNA-binding protein 1 S(0.003)QS(0.997)GGYSDR;S(0.003)QS(0.991)GGYS(0.006)DR 94.402 0.0057588 22615000.0 22270.0 32175.0 31148.0 29312.0 35374.0 30283.0 31755.0 30216.0 37277.0 27344.0 True False 21952.425716182188 32100.50076432611 28587.13167475705 31467.702261965536 33293.37086795982 28987.8666831209 33399.11852159169 31619.94566893121 33078.47171578772 32070.373966410276 0.6845079430372287 1.0009393965267566 0.8913875374418306 0.9812078367069881 1.0381347876651044 0.9038830265428798 1.041432150325815 0.985955003270282 1.0314339256047746 1.0 14.968953556414133 -4.759383958373022 24.999854455790185 0.9832850563664927 0.6845075624211793 0.7726349585526169 0.049051244837332385 24.89802042378782 302756.11295860977 0.011987348283145446 0.07642472251145108 1.740267627984503e-05 4.759383958373022 -0.2987774939453134 SQS(ph)GTLDGESAAWSASGEDSR ddPTM_PC-9_AZD4547_30min_R2 1 SQSGTLDGESAAWSASGEDSR 21 0 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4 P49815 TSC2 Tuberin 1 S(0.001)QS(0.987)GT(0.013)LDGESAAWSASGEDSR 224.08 5.714600000000001e-41 14515000.0 18000.0 21635.0 31028.0 46902.0 43054.0 29937.0 32844.0 38119.0 32790.0 36524.0 True False 23723.625576741364 28628.090654515843 30616.54844666494 36089.468528676494 37076.695266136056 28065.034657469892 35767.0523727412 32228.584437478123 34523.21245788826 35245.305877040395 0.6731002891422054 0.8122525806525868 0.8686702437333439 1.0239510661244113 1.0519612284110909 0.7962772334954284 1.0148032903309454 0.9144078519253983 0.9795123520371396 1.0 15.105143505461736 -5.047335600830384 1.5602126190640933 0.9616303185003408 0.6457705422355733 0.6325210968997048 0.07102329037048231 0.43021193629401094 1.431421055755686 0.020556960069963295 0.17912652642595836 8.967355747532104e-06 5.047335600830384 -0.31585977626476747 SQS(ph)GTLDGESAAWSASGEDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSGTLDGESAAWSASGEDSR 21 0 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4 P49815 TSC2 Tuberin 1 S(0.008)QS(0.523)GT(0.1)LDGES(0.367)AAWS(0.001)ASGEDSR 99.31299999999999 0.00023299 9950100.0 4941.6 6190.7 6775.0 7867.8 9924.7 9381.3 9333.2 7828.5 9780.7 6938.6 True False 5778.115278951105 6805.271783089017 6936.54169433058 7426.992673751762 7980.026280055076 8889.328113165207 8449.091729483544 7623.010169981388 9923.724234233501 8196.513254072617 0.7049479577282599 0.830264232136472 0.8462795678252588 0.906116106145683 0.9735879187519187 1.0845255583218083 1.030815356186416 0.9300308477136577 1.210725088415209 1.0 13.000794611363764 -5.533358866315641 0.6399420429352676 1.0587234791921294 0.6639900778421194 0.7263173315605231 0.0707897107194297 0.8278351423688659 0.4777081870936788 0.03801783205861391 0.21145541842505244 2.9284723892123013e-06 5.533358866315641 -0.39473340135001 SQS(ph)IEQESQEK ddPTM_PC-9_AZD4547_30min_R2 4 SQSIEQESQEK 11 0 A0A0A0MRN0;Q5VTL8 A0A0A0MRN0 PRPF38B Pre-mRNA-splicing factor 38B 1 S(0.209)QS(0.79)IEQESQEK;S(0.023)QS(0.977)IEQESQEK;S(0.301)QS(0.541)IEQES(0.158)QEK;SQS(0.993)IEQES(0.007)QEK 203.85 7.802100000000001e-06 228968000.0 346287.0 339717.0 431759.0 524853.0 466664.0 448623.0 432655.0 460252.0 400370.0 422464.0 True False 456399.0627829465 449523.87672198634 426033.59355368064 403856.2497480161 401875.7588069892 420570.5328903396 471160.4568362054 389130.6289388027 421532.7408284449 407673.66394803306 1.1195205948872002 1.102656159754504 1.0450358490853802 0.9906361029970688 0.985778072871092 1.0316352761603715 1.1557294436764625 0.9545150039135368 1.0339955167724018 1.0 18.637055234994463 -5.288700806238931 3.152106088174625 1.0240343188406753 1.1154159883571042 0.3266556930993507 0.050597298714365746 0.30630509162493325 6.16310185314835 0.014075729004136872 0.038686499213990554 5.143979080822522e-06 5.288700806238931 0.0913816695164289 SQS(ph)IEQESQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQSIEQESQEK 11 0 A0A0A0MRN0;Q5VTL8 A0A0A0MRN0 PRPF38B Pre-mRNA-splicing factor 38B 1 S(0.137)QS(0.803)IEQES(0.059)QEK;S(0.005)QS(0.994)IEQESQEK 177.93 0.0021464 150772000.0 188672.0 186694.6 184458.0 242660.0 248601.0 174341.0 204316.0 192910.0 187878.0 141343.3 True False 220610.44315813997 205228.40606637252 188856.17828086016 229064.54691433467 199889.41864721067 165198.2510502102 184961.70936025845 187846.31690504032 190625.36031974465 166967.7214170527 1.321276000449801 1.2291501873811412 1.1310939424581017 1.3719091628625406 1.1971740223245066 0.9894023206891427 1.1077692609714682 1.1250456993171571 1.1416898949204666 1.0 17.349209698976942 -6.556544881888454 8.829319696754023 1.083625464630666 1.2555936545689814 0.5938907051334881 0.0745581436232017 0.21180213918506047 50.96966897530776 0.024536118114055688 0.024627582354037825 2.7762279237615975e-07 6.556544881888454 0.17196818993831542 SQS(ph)IEQESQEK ddPTM_PC-9_Lapatinib_30min_R1 3 SQSIEQESQEK 11 0 A0A0A0MRN0;Q5VTL8 A0A0A0MRN0 PRPF38B Pre-mRNA-splicing factor 38B 1 S(0.015)QS(0.984)IEQES(0.001)QEK;SQS(1)IEQESQEK;S(0.003)QS(0.525)IEQES(0.473)QEK 193.45 0.00012499 139115000.0 401240.0 394723.0 461893.0 348584.0 387604.0 358120.0 312451.0 324829.0 384248.0 280626.0 True False 395518.24402159516 393809.0431452089 423917.9404985411 374220.03020213486 364805.8947787843 342804.04241849383 328628.1839455156 339921.74118656473 340969.94392917893 329131.83018935897 1.2017015911042155 1.1965085325191407 1.2879882819435877 1.1369913082755787 1.1083883760768474 1.041540230919838 0.9984697735142979 1.0327829459429616 1.0359676963878248 1.0 18.328306030026255 -6.349880748583277 1.503547581006371 1.019786737991737 1.2242364243721975 0.8864796008179175 0.03171722925102712 0.12273984091814975 0.5567274689830145 0.01219364855209836 0.015531690526274247 4.468062622915479e-07 6.349880748583277 0.20444968638046057 SQS(ph)LLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSLLLR 7 0 Q5TB30 Q5TB30 DEPDC1 DEP domain-containing protein 1A 1 S(0.019)QS(0.981)LLLR 79.97399999999999 0.026083999999999996 1613700.0 12668.0 12655.0 12173.0 17200.0 15922.0 16014.0 13256.0 14056.0 12419.0 10971.0 True False 14812.442195595067 13911.30476601863 12463.250486359575 16236.339763152384 12802.198397033348 15174.197648964182 12000.295714870987 13687.044893563047 12600.604380560275 12959.955453611788 1.1429392831336478 1.0734068350629793 0.9616738677050168 1.2528083002497903 0.9878273457695816 1.1708526085045539 0.9259519261330983 1.0561027730808 0.9722721984394347 1.0 13.661773138901323 -7.26515922196464 24.99396705806026 0.9932569589332462 1.0929200480099637 0.2850418255360271 0.0847088328042523 466.6067907146136 3135158.3343952284 0.03275543955016271 0.0230391454749441 5.4305120040814515e-08 7.26515922196464 0.0996630890767175 SQS(ph)LNIR ddPTM_PC-9_AZD4547_30min_R2 1 SQSLNIR 7 0 O00443;A0A0C4DGF9;O00443-2 O00443 PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 1 S(0.077)QS(0.923)LNIR 94.40899999999999 0.013456999999999998 70089000.0 91196.0 94146.0 134960.0 175960.0 145090.0 121350.0 99418.0 114100.0 95357.0 124930.0 True False 120194.43100536118 124576.8533746267 133170.34221870237 135395.14055489996 124946.7579357011 113761.96531663042 108266.00940181424 96468.4667571619 100397.3763448262 120556.23872573246 0.9969988469763528 1.0333505315974665 1.1046325235947947 1.1230869674270965 1.0364188469744577 0.9436422910923827 0.8980539750258906 0.8001947288404488 0.8327845776047474 1.0 16.87934678606397 -6.930852632108386 2.067082374139413 0.8650587593745337 1.066614601747614 0.6653291834094897 0.05918606654821815 0.18374934426938785 1.5948707653423602 0.025773563211665566 0.021091578050174038 1.1725931907069793e-07 6.930852632108386 0.20155584237308022 SQS(ph)LNIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQSLNIR 7 0 O00443;A0A0C4DGF9;O00443-2 O00443 PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 1 S(0.028)QS(0.972)LNIR;S(0.001)QS(0.999)LNIR 104.42 0.010352 118366000.0 172885.0 160143.0 179980.0 182647.0 193882.0 183645.0 206829.0 169245.0 147659.0 167660.0 True False 202151.01586560305 176040.93869178323 184271.40577795118 172413.88073956312 155892.2138935824 174014.33291145426 187236.65980771312 164802.4980799001 149818.2335316171 198055.43080417038 1.0206789838824577 0.8888468141317759 0.9304031958616257 0.8705334665124096 0.7871140582240467 0.8786142960326746 0.9453750348953852 0.8321028987225829 0.7564459753681363 1.0 17.59554473582488 -1.5228823170386223 0.8847667843774087 0.8635871683354645 69.5157955471824 0.2826214551813253 0.06888716633675505 1053.8471880442112 2.4999510264287337 0.023174995491900812 145951.74445923432 0.02999975327269311 1.5228823170386223 68.65220837884694 SQS(ph)LNIR ddPTM_PC-9_Lapatinib_30min_R1 3 SQSLNIR 7 0 O00443;A0A0C4DGF9;O00443-2 O00443 PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 1 SQS(1)LNIR;S(0.001)QS(0.999)LNIR;S(0.008)QS(0.992)LNIR 114.86 0.008479899999999999 148274000.0 300346.0 213533.0 302200.0 197536.0 249242.0 251389.0 243903.0 222259.0 250300.0 161531.0 True False 296063.01096328866 213038.5774579285 277354.28252573445 212063.4564007788 234582.0755886255 240637.67848638116 256531.10391345568 232585.96453637036 222108.57822415093 189451.41812347202 1.5627384260081612 1.1245024163349568 1.463986309909663 1.1193553392277578 1.2382175753139006 1.2701814579690784 1.3540732840873513 1.2276813065858714 1.172377490884735 1.0 17.531468413502452 -14.522878745070676 0.10176993905446666 0.11915798755878658 1.4578350686141186 0.37303680014091634 0.126863747193444 209.0305400838766 1.4363116606218647 38.91623811740787 1.9409158555685646 3.0000000014482925e-15 14.522878745070676 1.3386770810553321 SQS(ph)LPGADSLLAKPIDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSLPGADSLLAKPIDK 17 1 H0Y4W2;F2Z2U4;Q9Y4A5-2;Q9Y4A5 H0Y4W2 TRRAP Transformation/transcription domain-associated protein 1 S(0.212)QS(0.788)LPGADSLLAKPIDK 88.945 0.0012454 18304000.0 34604.0 32331.0 21869.0 31943.0 36056.0 33937.0 42570.0 61371.0 41869.0 32851.0 True False 40461.77373984622 35540.60801186475 22390.43989864434 30153.337270603293 28991.08563016167 32157.283977325907 38537.4614198897 59760.076277949505 42481.25491663403 38806.62625162707 1.0426511564671188 0.9158386452204053 0.576974657715976 0.7770151693962067 0.7470653450310214 0.8286544614523822 0.9930639466056114 1.5399451601501664 1.0946907530992311 1.0 15.244015393924665 -7.538587635009423 7.224466665246992 1.2451771660659487 0.8119245629210146 0.5152273068533217 0.17168469897166241 0.11382547387394804 29.077390534399395 0.07988244284824746 0.04709246791324891 2.8934259022293572e-08 7.538587635009423 -0.4332526031449342 SQS(ph)LPGADSLLAKPIDK ddPTM_PC-9_Lapatinib_30min_R1 1 SQSLPGADSLLAKPIDK 17 1 H0Y4W2;F2Z2U4;Q9Y4A5-2;Q9Y4A5 H0Y4W2 TRRAP Transformation/transcription domain-associated protein 1 S(0.178)QS(0.817)LPGADS(0.005)LLAKPIDK 91.565 0.0010354000000000001 15109000.0 40888.0 51564.0 41127.0 41864.0 78471.0 76441.0 102800.0 83208.0 74931.0 78164.0 True False 40304.92962205915 51444.60672608269 37745.696814810995 44942.8182142101 73855.49005992182 73171.79662267433 108122.48099573687 87074.14744573829 66491.48172158943 91674.54325301695 0.4396523635882172 0.5611656726131513 0.4117358590010625 0.49024316478098257 0.805627030571448 0.7981691975352851 1.1794166314777754 0.9498181758639167 0.7252992964260145 1.0 16.484233552613482 -6.444319107761055 1.9073584763388034 0.9498954647211062 0.46877775223369533 0.7712031285395825 0.11763274226411505 0.16362719156533073 1.1855224898950723 0.04414314619673244 0.05066660892646279 3.5948509822786436e-07 6.444319107761055 -0.48111771248741086 SQS(ph)LPHSATVTLGGTSDPSTLSSSALSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSLPHSATVTLGGTSDPSTLSSSALSER 29 0 F8WDP1;A0A0A0MRY0;Q8WUA7-3;Q8WUA7-4;Q8WUA7 F8WDP1 TBC1D22A TBC1 domain family member 22A 1 S(0.034)QS(0.38)LPHS(0.38)AT(0.197)VT(0.008)LGGTSDPSTLSSSALSER 107.36 1.2527999999999998e-11 55023000.0 38437.0 36847.0 65504.0 55849.0 76077.0 58345.0 60405.0 61810.0 57966.0 44649.0 True False 44943.62493464539 40504.9266466605 67065.86378530337 52719.96159490099 61170.257973314045 55285.28548949761 54683.00110567156 60187.552993108446 58813.64308910194 52743.51025871047 0.8521166815442105 0.7679603888323152 1.2715472189154797 0.9995535249039366 1.1597684278742504 1.048191241317075 1.0367721230052334 1.1411366573420019 1.1150877672080803 1.0 15.686705970173788 -5.243941768662978 24.95511208904746 1.096485461649738 0.8100384818656761 0.6684172564505897 0.08070660344686204 428.83609247626777 611604.328523605 0.019047447125424544 0.050137911233571024 5.702407265191666e-06 5.243941768662978 -0.28644697978406186 SQS(ph)LPHSATVTLGGTSDPSTLSSSALSER ddPTM_PC-9_Lapatinib_30min_R1 2 SQSLPHSATVTLGGTSDPSTLSSSALSER 29 0 F8WDP1;A0A0A0MRY0;Q8WUA7-3;Q8WUA7-4;Q8WUA7 F8WDP1 TBC1D22A TBC1 domain family member 22A 1 S(0.058)QS(0.85)LPHS(0.087)AT(0.006)VTLGGTSDPSTLSSSALSER;S(0.067)QS(0.894)LPHS(0.025)AT(0.014)VTLGGTSDPSTLSSSALSER 174.55 3.2381e-19 120652000.0 137211.0 110478.0 164985.0 102250.0 151914.0 167278.0 151723.0 152938.0 182873.0 153170.0 True False 135254.34597858432 110222.1949787481 151420.57016051732 109769.80609600061 142978.71719441554 160123.9098840635 159578.4745536593 160044.05780761893 162275.91700193816 179645.23041380433 0.7528969495434547 0.6135548086907539 0.8428866706437302 0.6110365738247046 0.7958948693771095 0.891334044968662 0.8882978645526953 0.8908895462404706 0.9033132503887981 1.0 17.454791106689235 -6.618485581465162 3.1476488453673808 0.9076650207374309 0.7073511291413265 0.6669972092917038 0.06972756605815841 0.15021239407064124 2.980764631009963 0.02283775023434663 0.02295424540805008 2.407212436943852e-07 6.618485581465162 -0.20031389159610447 SQS(ph)LPNSLDYTQTSDPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQSLPNSLDYTQTSDPGR 18 0 H0YNE5;H0YLG5;Q96TC7 H0YNE5 RMDN3 Regulator of microtubule dynamics protein 3 1 S(0.003)QS(0.997)LPNSLDYTQTSDPGR;S(0.033)QS(0.963)LPNS(0.003)LDYT(0.001)QTSDPGR 254.54 4.010599999999999e-65 117212000.0 80715.0 98679.0 91221.0 91062.0 120954.0 91587.0 88877.0 93539.0 81826.0 69264.0 True False 94378.45530608264 108475.19897320858 93396.05459756916 85960.09136698725 97253.93197555408 86784.01649030119 80457.92714624217 91083.70036276281 83022.5504504168 81821.01490647787 1.1534745128003856 1.325762080771018 1.1414678087814196 1.0505869606389067 1.1886180107484143 1.0606568079055982 0.9833406153444355 1.1132066800549012 1.014684925936354 1.0 16.320183812051155 -5.805897631100835 0.5588242913572613 1.0260678046153107 1.275294575788243 0.5155568482871289 0.06902593670545797 1.2472248375992692 0.6324875773466508 0.04704762975327006 0.17828287586501512 1.5635161404476157e-06 5.805897631100835 0.24922677117293235 SQS(ph)LPNSLDYTQTSDPGR ddPTM_PC-9_Lapatinib_30min_R1 1 SQSLPNSLDYTQTSDPGR 18 0 H0YNE5;H0YLG5;Q96TC7 H0YNE5 RMDN3 Regulator of microtubule dynamics protein 3 1 S(0.03)QS(0.711)LPNS(0.259)LDYTQTSDPGR 191.89 2.0898000000000002e-11 87370000.0 105900.0 81438.0 85263.0 64867.0 57395.0 66433.0 57788.0 45688.0 85443.0 53678.0 True False 104389.84658031841 81249.435314536 78253.00526469786 69637.53556996869 54019.138942911566 63591.81545288679 60779.97988114443 47810.83127224415 75819.50958532207 62956.170778560925 1.6581352596474512 1.2905714294523873 1.2429759354319896 1.1061272423144743 0.8580435924687343 1.0100966222447303 0.9654332391804621 0.7594304208941125 1.2043221283582517 1.0 15.942060173146054 -4.495217322050866 0.7129914169370817 0.9511576925088283 2.33471676598181 0.761084057988096 0.11862724638256034 1.9123760362402538 0.5558247122595226 0.04742410147549147 2.337322467001991 3.197294774973389e-05 4.495217322050866 1.383559073472982 SQS(ph)LPTTLLSPVR ddPTM_PC-9_Lapatinib_30min_R1 2 SQSLPTTLLSPVR 13 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 S(0.008)QS(0.845)LPT(0.073)T(0.073)LLSPVR;SQS(0.62)LPT(0.19)T(0.19)LLSPVR 182.7 6.5535e-05 260870000.0 84767.0 59341.0 76496.0 64538.0 79316.0 70705.0 68300.0 67724.0 95714.0 56856.0 True False 83558.20703563599 59203.599560400195 70206.79416309934 69284.33981245688 74650.78882125574 67681.11197140512 71836.23980553329 70870.70427861706 84933.68140689723 66683.48384414215 1.253057012302098 0.8878300314778915 1.0528363264161806 1.0390030007189435 1.1194794350537445 1.0149606479708635 1.077271847005393 1.0627924666362907 1.27368392457435 1.0 16.02504185869938 -8.045684226477054 24.991873210796957 1.147307434850229 1.0566959344162252 0.06780809356996087 0.10544134404765516 938.4117346835428 513359.20649767166 0.06553922584103727 0.024773840063921856 9.001518399152117e-09 8.045684226477054 -0.09061150043400379 SQS(ph)LQDQPTR ddPTM_PC-9_AZD4547_30min_R2 2 SQSLQDQPTR 10 0 Q8N4C8;Q8N4C8-3;Q8N4C8-2 Q8N4C8;Q8N4C8-3 MINK1 Misshapen-like kinase 1 1 S(0.001)QS(0.999)LQDQPTR;S(0.154)QS(0.845)LQDQPTR 149.69 0.00015738 37319000.0 24335.0 27304.0 35682.0 48211.0 43822.0 38355.0 31810.0 41948.0 35727.0 32806.0 True False 32073.023800555624 36129.48404117867 35208.833365795355 37096.6988025249 37738.07172278099 35956.655786727395 34641.028375864604 35465.90046914485 37615.4562818839 31657.47192536924 1.0131265022098426 1.141262452237246 1.1121808288671393 1.17181494750997 1.1920747118325314 1.1358031327167641 1.0942449371045464 1.120301095196539 1.1882015206571226 1.0 14.950258430149054 -4.759406048770315 24.985490377723856 1.1341897100806186 1.013126346926515 0.2940105907174507 0.052930127280224476 63.12708259093 775504.4578785612 0.012496206988738427 0.08016327928765683 1.740179111488878e-05 4.759406048770315 -0.1210633631541036 SQS(ph)LQDQPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SQSLQDQPTR 10 0 Q8N4C8;Q8N4C8-3;Q8N4C8-2 Q8N4C8;Q8N4C8-3 MINK1 Misshapen-like kinase 1 1 S(0.035)QS(0.965)LQDQPTR;S(0.027)QS(0.972)LQDQPT(0.001)R;S(0.003)QS(0.994)LQDQPT(0.003)R 129.76 0.00023557 26517000.0 52459.0 66499.0 68652.0 79643.0 83774.0 65560.0 68908.0 59561.0 60659.0 57301.0 True False 61339.27258752147 73100.58124341948 70288.92404415998 75180.86091608998 67359.08607669092 62121.91818821598 62380.53538928259 57997.58686009594 61546.02311944651 67689.21770553368 0.9061897103666321 1.0799442469763307 1.0384065058919092 1.1106770541084838 0.9951228328523617 0.9177520481690755 0.9215727039519752 0.8568216449538693 0.9092441190144681 1.0 16.046638423074654 -6.659964596827211 3.587960157266204 0.9114342887225608 1.0389304149058134 0.4399498749557117 0.059685627324722774 0.19624454487150805 4.889603399684203 0.020314509275140735 0.020031269369778202 2.187939974960385e-07 6.659964596827211 0.12749612618325257 SQS(ph)LQDQPTR ddPTM_PC-9_Lapatinib_30min_R1 4 SQSLQDQPTR 10 0 Q8N4C8;Q8N4C8-3;Q8N4C8-2 Q8N4C8;Q8N4C8-3 MINK1 Misshapen-like kinase 1 1 S(0.004)QS(0.996)LQDQPTR;S(0.402)QS(0.596)LQDQPT(0.002)R;S(0.083)QS(0.903)LQDQPT(0.015)R;S(0.001)QS(0.999)LQDQPTR 123.28 0.00046875 64504000.0 124283.0 105819.0 101872.0 86939.5 107425.0 85415.0 71884.0 79786.0 115099.0 83948.0 True False 122510.70162928889 105573.98260699984 93496.47739729186 93333.32085167032 101106.47270567618 81761.99956208993 75605.80178888676 83493.14883311305 102135.3385737975 98458.29994632109 1.2442902395844844 1.0722710291012356 0.9496048321803812 0.947947719009521 1.0268963892409158 0.8304226216242421 0.7678966814388083 0.8480051847191455 1.0373461519189455 1.0 16.587225208699863 -3.4225373599545317 0.6883719720921277 0.8975807954983697 3.2434923312237762 0.592547379228421 0.08332923923396592 11.717688195899894 0.9769429803206235 0.03551804899471014 32.701309422529484 0.00037797462083513905 3.4225373599545317 2.3459115357254063 SQS(ph)MDAMGLSNK ddPTM_PC-9_AZD4547_30min_R2 2 SQSMDAMGLSNK 12 0 J3KPC5;P47736-3;F2Z357;P47736;A0A0A0MQY8;X6R8W7;P47736-2;P47736-4 J3KPC5;P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 S(0.006)QS(0.992)MDAMGLS(0.003)NK;S(0.005)QS(0.995)MDAMGLSNK 90.861 0.0040158 34445000.0 95333.0 88614.0 89280.0 93262.0 119435.0 92185.0 92699.0 154162.0 117530.0 105367.0 True False 125646.91095041575 117256.74255878293 88096.08886548434 71761.88678353645 102853.51184816631 86420.65737712079 100949.03141824206 130339.80519033817 123742.39585774939 101678.13340121869 1.2357318800751096 1.1532149404837277 0.8664211853482792 0.70577502146274 1.011559795677106 0.8499433898546074 0.9928293138496198 1.2818862899068124 1.2170010573410688 1.0 16.63364992525893 -7.6614487206161 6.643158010331149 1.1857431608819018 0.9607972878138259 0.23657698378983893 0.15698789582630066 0.2926857108133085 16.64307023049299 0.08051456808987836 0.0458754296256312 2.1804758419878234e-08 7.6614487206161 -0.2249458730680759 SQS(ph)MDAMGLSNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SQSMDAMGLSNK 12 0 J3KPC5;P47736-3;F2Z357;P47736;A0A0A0MQY8;X6R8W7;P47736-2;P47736-4 J3KPC5;P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 S(0.002)QS(0.998)MDAMGLSNK;S(0.001)QS(0.999)MDAMGLSNK;S(0.005)QS(0.995)MDAMGLSNK;S(0.002)QS(0.998)MDAMGLSNK 84.89200000000001 0.0059548000000000005 49171600.0 426317.0 537320.0 352005.0 339358.0 378801.0 232842.0 200631.0 253494.0 173385.0 178306.0 True False 498484.0479554399 590661.57857583 360398.1341863973 320344.8714734801 304577.66329573054 220631.3556250854 181625.7792373478 246840.05109909433 175920.42761280626 210631.46633048097 2.366617185170795 2.804241877370219 1.7110365344033274 1.5208785138059984 1.4460216633437282 1.047475761664758 0.8622917667599426 1.171904917149473 0.835204875499404 1.0 17.684361451768545 -5.613711187908438 0.8602166283191834 0.9789567434411558 2.814319571419129 0.8895502886552986 0.2076928354843089 0.2622825033789035 0.3209348130166755 0.08551072399315918 0.3639285902541053 2.433821997737489e-06 5.613711187908438 1.8353628279779732 up SQS(ph)MDAMGLSNK ddPTM_PC-9_Lapatinib_30min_R1 4 SQSMDAMGLSNK 12 0 J3KPC5;P47736-3;F2Z357;P47736;A0A0A0MQY8;X6R8W7;P47736-2;P47736-4 J3KPC5;P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 S(0.002)QS(0.998)MDAMGLSNK;S(0.007)QS(0.991)MDAMGLS(0.002)NK;S(0.006)QS(0.99)MDAMGLS(0.004)NK;S(0.052)QS(0.947)MDAMGLS(0.001)NK 96.135 0.002617 19261500.0 89449.40000000001 159697.0 156200.0 147628.0 129095.0 122359.0 118696.3 117572.0 123131.0 166116.0 True False 88173.83515298921 159327.23140825416 143357.83894943647 158485.05559257144 121501.88591053523 117125.9908027603 124841.8136285437 123034.82433768781 109262.69015308793 194828.92926434294 0.45257054733055263 0.8177801521050283 0.7358139239934397 0.8134575095751807 0.6236336994167949 0.6011735076768006 0.6407765730681553 0.631501824714926 0.5608134816818751 1.0 17.571848387008238 -10.502109962428477 5.588015523583877 1.000000668762161 0.6616676720362494 0.4873486278084018 0.10642116637253768 8.972891780400488e-07 1.6406215139810514e-07 0.1042780782783085 0.02529109877140741 3.146951411891467e-11 10.502109962428477 -0.33833299672591155 SQS(ph)MDIDGVSCEK ddPTM_PC-9_AZD4547_30min_R2 6 SQSMDIDGVSCEK 13 0 O95155-2;O95155;O95155-4 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 SQS(1)MDIDGVSCEK;S(0.004)QS(0.996)MDIDGVSCEK;SQS(1)MDIDGVSCEK;SQS(0.52)MDIDGVS(0.48)CEK;S(0.015)QS(0.981)MDIDGVS(0.004)CEK;S(0.01)QS(0.975)MDIDGVS(0.015)CEK 163.02 7.053699999999999e-05 55694700.0 177602.0 183838.0 227809.0 323482.0 274667.0 246560.0 253724.0 315733.0 274388.0 253104.0 True False 234075.74164891272 243260.03835197058 224788.10381224385 248908.22264707953 236534.22814753055 231142.5642230608 276304.94447148294 266943.7196725588 288891.58950579574 244242.9059988621 0.9583727342729997 0.9959758600034996 0.9203465005173626 1.0191011347049694 0.9684384779987533 0.9463634707332612 1.1312711144731067 1.0929435947417137 1.1828044230162478 1.0 17.897957134362755 -7.261785787189303 24.996266345144825 1.1095000872676004 0.969529838925895 0.6364080849577072 0.049345670864997665 18.44140067225854 1330618.2630851865 0.018478095273554384 0.013337356912732972 5.472858413638307e-08 7.261785787189303 -0.13997024834170546 SQS(ph)MDIDGVSCEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SQSMDIDGVSCEK 13 0 O95155-2;O95155;O95155-4 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 S(0.042)QS(0.958)MDIDGVSCEK;S(0.008)QS(0.992)MDIDGVSCEK;S(0.082)QS(0.918)MDIDGVSCEK;S(0.016)QS(0.978)MDIDGVS(0.005)CEK 123.72 0.00014308 31017700.0 178720.0 181446.0 178407.0 218934.0 233471.0 218740.0 203041.0 253026.0 188838.0 158240.0 True False 208973.76611909972 199458.75974516085 182660.89949231507 206667.83777360502 187724.03353559657 207268.8893302376 183807.48659045837 246384.33560320712 191599.39850360286 186927.65937284904 1.1179392435566593 1.0670371651490969 0.9771742721497229 1.1056033037966944 1.0042603334649318 1.1088187271248906 0.9833081268290685 1.3180731863322848 1.0249922303977257 1.0 17.51212053248527 SQS(ph)MDIDGVSCEK ddPTM_PC-9_Lapatinib_30min_R1 7 SQSMDIDGVSCEK 13 0 O95155-2;O95155;O95155-4 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 S(0.002)QS(0.998)MDIDGVSCEK;S(0.006)QS(0.994)MDIDGVSCEK;S(0.002)QS(0.998)MDIDGVSCEK;SQS(0.994)MDIDGVS(0.005)CEK;SQS(1)MDIDGVSCEK;S(0.009)QS(0.883)MDIDGVS(0.108)CEK;S(0.163)QS(0.836)MDIDGVS(0.001)CEK 257.37 6.483199999999999e-44 105578000.0 327601.0 396468.0 418436.0 398750.0 479767.0 424056.0 457017.0 456568.0 519501.0 528192.0 True False 322929.3496653338 395550.00270492164 384033.8072896706 428075.40519100655 451548.048318214 405920.1134028177 480679.1040586455 477781.8160634298 460989.3267919483 619489.2834284011 0.5212831897239061 0.638509839130475 0.6199200172831661 0.6910134148276713 0.7289037282763629 0.6552496132884804 0.7759280376868716 0.771251140002409 0.7441441508733189 1.0 19.240719799775363 -14.522878745280336 0.04856649550778807 2.3623320534745615 1.136403383294797e-15 0.892991843999046 0.0394862682839604 173.32757564643225 0.6211510093536645 30.745198221411698 7.14287470320087 3.0000000000000132e-15 14.522878745280336 -2.36233205347456 SQS(ph)NPILGSPFFSHFDGQDSYAAAVR ddPTM_PC-9_AZD4547_30min_R2 3 SQSNPILGSPFFSHFDGQDSYAAAVR 26 0 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 S(0.248)QS(0.729)NPILGS(0.023)PFFSHFDGQDSYAAAVR;S(0.176)QS(0.811)NPILGS(0.013)PFFSHFDGQDSYAAAVR;S(0.191)QS(0.792)NPILGS(0.017)PFFSHFDGQDSYAAAVR 179.95 3.9592000000000005e-18 31494500.0 6997.6 7912.700000000001 17176.1 32530.1 25782.100000000002 21202.3 15012.400000000001 30587.0 18856.5 20919.2 True False 9222.69124087808 10470.32553371794 16948.333691335625 25030.788030034957 22202.700446440413 19876.516829277283 16348.474517127626 25860.48196933666 19853.21609369229 20186.825175308917 0.45686685057136267 0.5186712344705147 0.8395740065191438 1.2399566456171043 1.099860936706242 0.9846281748944267 0.8098586268594584 1.2810574097093461 0.9834739203059689 1.0 14.301126412358723 -5.385475577718851 3.0028770093433383 1.0569830904881634 0.4754973042390076 0.7520883809773509 0.12924769536892483 0.123694389167512 2.0997176542859655 0.03592542438146285 0.08901352868413864 4.1164649533755606e-06 5.385475577718851 -0.5814857862491558 down SQS(ph)NPILGSPFFSHFDGQDSYAAAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQSNPILGSPFFSHFDGQDSYAAAVR 26 0 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 S(0.072)QS(0.927)NPILGS(0.001)PFFSHFDGQDSYAAAVR;S(0.152)QS(0.847)NPILGS(0.001)PFFSHFDGQDSYAAAVR 148.6 9.297799999999999e-10 20622100.0 5777.3 5905.1 11819.2 14110.5 17761.4 17280.8 11709.8 13823.6 12288.5 6296.8 True False 6755.282783123729 6491.319302553665 12101.014552565612 13319.93443185823 14281.181171276734 16374.564426890236 10600.562972389573 13460.745147314898 12468.196064942022 7438.359994558625 0.9081683043124309 0.8726815194884695 1.6268390561115424 1.7907084950986705 1.919936811571883 2.201367564741247 1.425120991743367 1.809638839362685 1.6762022911048762 1.0 12.86076885646201 -5.299686694500236 4.18163905811362 1.7398065575277033 0.8773499673064065 0.5198506827283873 0.3012337694752754 0.14080982963736488 5.558418017003622 0.07685167459949 0.18383019160101574 5.015489268485251e-06 5.299686694500236 -0.8624565902212968 SQS(ph)PAASDCSSSSSSASLPSSGR ddPTM_PC-9_AZD4547_30min_R2 5 SQSPAASDCSSSSSSASLPSSGR 23 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 S(0.011)QS(0.989)PAAS(0.001)DCSSSSSSASLPSSGR;S(0.001)QS(0.996)PAAS(0.003)DCSSSSSSASLPSSGR;S(0.007)QS(0.993)PAASDCSSSSSSASLPSSGR;S(0.003)QS(0.982)PAAS(0.014)DCSSSSSSASLPSSGR;S(0.023)QS(0.971)PAAS(0.006)DCSSSSSSASLPSSGR 305.9 8.876399999999997e-161 725037000.0 82784.5 77194.8 133016.2 183109.0 144774.4 138781.3 118236.3 161467.5 105996.2 122178.7 True False 109108.24897543022 102146.50947340987 131252.318276759 140896.04905584888 124674.97354804861 130103.283372039 128759.10164593671 136516.40802902746 111598.94273646892 117901.26090130207 0.9254205437783003 0.8663733423421072 1.113239309515387 1.1950342852889104 1.057452419040853 1.1034935706154283 1.0920926600922785 1.157887600059753 0.9465457950436258 1.0 16.847219621815796 -5.263072320084355 24.999856240864208 1.0929713413153153 0.8958969314447764 0.5344493934551762 0.06945663502544397 92.73051253729552 1419701.781526829 0.017325539623143135 0.0394083101673487 5.456669873406108e-06 5.263072320084355 -0.1970744098705388 SQS(ph)PAASDCSSSSSSASLPSSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 SQSPAASDCSSSSSSASLPSSGR 23 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 S(0.025)QS(0.963)PAAS(0.012)DCSSSSSSASLPSSGR;S(0.028)QS(0.656)PAAS(0.259)DCS(0.008)S(0.023)S(0.023)S(0.003)SSASLPSSGR;S(0.034)QS(0.787)PAAS(0.166)DCS(0.004)S(0.004)S(0.004)S(0.001)SSASLPSSGR;S(0.031)QS(0.966)PAAS(0.003)DCSSSSSSASLPSSGR;S(0.043)QS(0.841)PAAS(0.104)DCS(0.006)S(0.006)S(0.001)SSSASLPSSGR;S(0.124)QS(0.873)PAAS(0.004)DCSSSSSSASLPSSGR;S(0.048)QS(0.95)PAAS(0.002)DCSSSSSSASLPSSGR 252.84 5.6952999999999984e-145 392205300.0 99573.5 108472.5 135810.1 133104.8 151213.5 133850.7 129809.70000000001 133449.19999999998 120519.1 97651.8 True False 116429.32688372949 119240.93293022168 139048.32784667227 125647.36958758393 121584.30017019219 126831.33366130955 117513.18547515749 129946.29990111534 122281.46383776325 115355.2983287763 1.0093106131275573 1.0336840583634992 1.2053917753337 1.089220620187501 1.0539984026018683 1.0994842499546504 1.0187064415561646 1.1264874850460094 1.060042023290916 1.0 16.815724743712188 -8.543622889816449 21.90004067518231 0.9999999959896788 1.0811208120361642 0.16004234624016034 0.05471961185090188 1630.3875553965656 1721235.1729771935 0.05356477780092277 0.013830366155753407 2.860072947691564e-09 8.543622889816449 0.08112081604648536 SQS(ph)PAASDCSSSSSSASLPSSGR ddPTM_PC-9_Lapatinib_30min_R1 2 SQSPAASDCSSSSSSASLPSSGR 23 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 S(0.009)QS(0.991)PAAS(0.001)DCSSSSSSASLPSSGR;S(0.017)QS(0.972)PAAS(0.011)DCSSSSSSASLPSSGR 185.64 5.542e-42 72939000.0 51255.7 46927.0 58951.5 47468.9 46010.2 52193.5 53042.8 42915.9 53496.9 37597.0 True False 50524.78431885581 46818.34341468629 54104.735229370715 50959.92125760835 43303.97049553362 49961.30567399105 55789.09664358633 44909.92938619557 47471.515774668725 44095.591355146506 1.1458012641655828 1.0617465822741938 1.2269874054666923 1.1556693014314388 0.9820476189277708 1.1330226931668068 1.2651853604651806 1.0184675611784038 1.0765592277090124 1.0 15.42834680295113 SQS(ph)PHYFR ddPTM_PC-9_AZD4547_30min_R2 3 SQSPHYFR 8 0 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 S(0.016)QS(0.984)PHYFR;S(0.414)QS(0.582)PHY(0.004)FR;S(0.388)QS(0.558)PHY(0.054)FR 84.31 0.014072 55351000.0 59501.0 67960.0 137911.0 205850.0 173157.0 159756.0 113798.0 156986.0 136493.0 148902.0 True False 78421.08030231604 89926.7409697664 136082.21003055337 158394.46285079655 149117.1394573862 149766.4320652959 123925.80154406265 132727.42087940237 143707.74132401758 143688.98630224148 0.545769598077349 0.6258429632220432 0.9470608258333196 1.1023424058238045 1.0377770996569418 1.042295835745343 0.8624585970938085 0.9237132524563707 1.0001305251171906 1.0 17.13258995852795 -5.244658631112004 3.515071437891043 0.9931363618021022 0.5638442960693069 0.8717041026922325 0.06247856629490981 0.08178427431076314 2.167062263607588 0.018622148601293045 0.05272472888255756 5.693002426096785e-06 5.244658631112004 -0.4292920657327953 SQS(ph)PHYFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQSPHYFR 8 0 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 S(0.042)QS(0.958)PHYFR;S(0.006)QS(0.994)PHYFR 97.59700000000001 0.0057644 37234000.0 37386.0 44666.0 74406.0 73547.0 84821.0 81537.0 63899.0 62713.0 73627.0 60889.0 True False 43714.71139284156 49100.14529268971 76180.12122632621 69426.4000325913 68200.93394264333 77261.05618231506 57846.02413130212 61066.85019991604 74703.65558640078 71927.69370294124 0.607759113942701 0.6826319983992748 1.059120865753702 0.9652248870834064 0.9481874147711549 1.0741489432623883 0.8042246477442208 0.8490033123002653 1.0385937841261 1.0 16.134259725671882 -5.155324855241109 5.177412263453634 0.9586356522425539 0.6280534408780488 0.7077287390528548 0.08301229442336486 0.1207968350869474 4.762628532532725 0.021990354681885656 0.06195751724764851 6.993187051424215e-06 5.155324855241109 -0.33058221136450505 SQS(ph)PHYFR ddPTM_PC-9_Lapatinib_30min_R1 3 SQSPHYFR 8 0 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 S(0.001)QS(0.999)PHYFR;S(0.255)QS(0.642)PHY(0.103)FR;S(0.01)QS(0.98)PHY(0.009)FR 89.82700000000001 0.0056297 55315000.0 92693.0 64263.0 108067.0 67102.0 90099.0 100314.0 72194.0 82514.0 109300.0 65863.0 True False 91371.18082218543 64114.20297180694 99182.14841068331 72036.90492571013 84799.5539614494 96023.80406335533 75931.85207204496 86347.90167216695 96989.48301997475 77247.3317930689 1.1828393123914192 0.8299859876527109 1.2839556539813397 0.9325487787550187 1.097766770619489 1.243069525308461 0.982970548101935 1.1178107989992039 1.2555706555637596 1.0 16.23719748116985 -6.513460389528215 24.879859991925777 1.1244378961923132 1.0520153995519577 0.04054971760614734 0.14187723356447351 1404.1845677469755 3709356.7875093175 0.0432070845693698 0.04560434634143076 3.065770284796544e-07 6.513460389528215 -0.0724224966403555 SQS(ph)PLMTHPQILPATQDILK ddPTM_PC-9_AZD4547_30min_R2 2 SQSPLMTHPQILPATQDILK 20 0 Q03112;Q03112-3;E7EUL6;A0A0C3SFZ7;Q03112-8;Q03112-5;Q03112-6;Q03112-1;Q03112-4 Q03112 MECOM MDS1 and EVI1 complex locus protein EVI1 1 S(0.125)QS(0.776)PLMT(0.099)HPQILPATQDILK;S(0.425)QS(0.544)PLMT(0.031)HPQILPATQDILK 67.43 0.0035676 16005200.0 17779.7 18956.6 24731.1 42272.0 29838.0 22441.7 24431.7 29213.5 22490.7 25224.2 True False 23433.274759266038 25083.950233482577 24403.149454986305 32526.84349588961 25695.508741370544 21038.416951349238 26606.073969525653 24699.224834446544 23679.51248632592 24341.10843564895 0.9627036838201939 1.030517993862009 1.0025488165217034 1.3362926171534648 1.0556425073780946 0.8643163069984632 1.0930510432532123 1.0147124112997712 0.9728198101137381 1.0 14.571107245966044 -6.5341025733120395 24.982515268997528 0.992356717258767 1.088824464419596 0.1477365790181584 0.10745401405286309 445.9451249668367 992598.5590915013 0.03685064547438026 0.036877866220679456 2.92346182203591e-07 6.5341025733120395 0.09646774716082895 SQS(ph)PLMTHPQILPATQDILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSPLMTHPQILPATQDILK 20 0 Q03112;Q03112-3;E7EUL6;A0A0C3SFZ7;Q03112-8;Q03112-5;Q03112-6;Q03112-1;Q03112-4 Q03112 MECOM MDS1 and EVI1 complex locus protein EVI1 1 S(0.074)QS(0.596)PLMT(0.33)HPQILPATQDILK 86.508 0.00052127 7238000.0 21611.0 27129.0 26483.0 26329.0 35694.0 30895.0 26185.0 26986.0 28200.0 21841.0 True False 25269.31546329374 29822.18783068504 27114.4551573368 24853.8714897697 28700.016931522954 29274.811812460866 23704.567237016945 26277.646094030486 28612.371650841455 25800.600406739137 0.9794080395390091 1.155871854164117 1.0509234176680045 0.9633059346664603 1.1123778702462477 1.13465622314798 0.9187602948505529 1.0184897126334604 1.1089808453979964 1.0 14.655117018598997 -14.522864007936578 0.11501971640589656 0.8440410844188375 1.0749294356378831 0.026307320092108344 0.07555922578188101 671.5680470765574 5.053324250193662 24.625404245213172 0.8460215431270772 3.0001018036914474e-15 14.522864007936578 0.2308883512190456 SQS(ph)PLMTHPQILPATQDILK ddPTM_PC-9_Lapatinib_30min_R1 3 SQSPLMTHPQILPATQDILK 20 0 Q03112;Q03112-3;E7EUL6;A0A0C3SFZ7;Q03112-8;Q03112-5;Q03112-6;Q03112-1;Q03112-4 Q03112 MECOM MDS1 and EVI1 complex locus protein EVI1 1 S(0.161)QS(0.838)PLMTHPQILPATQDILK;S(0.149)QS(0.807)PLMT(0.044)HPQILPATQDILK;S(0.425)QS(0.534)PLMT(0.041)HPQILPATQDILK 113.6 1.6314e-05 20737300.0 45269.0 36202.9 40887.0 38607.6 44051.5 43980.5 40586.0 36255.0 47720.0 33602.0 True False 44623.45575868213 36119.07440934953 37525.4286883842 41446.93169517814 41460.47737858126 42099.55653855292 42687.34449117683 37939.53965538461 42345.271086122586 39410.0609281494 1.132285886084712 0.9164937469952191 0.9521789057063074 1.0516840298913077 1.0520277411945664 1.0682438835937573 1.083158551036052 0.9626866531506819 1.0744787013479762 1.0 15.2662763594406 -5.786200959269511 24.979209879657812 1.0434564918974254 0.9919369141731568 0.08024228545382772 0.06219055200179221 456.2626911586733 460271.0217355033 0.017182205789777895 0.02549805743466466 1.6360592993701743e-06 5.786200959269511 -0.05151957772426863 SQS(ph)PVHLR ddPTM_PC-9_AZD4547_30min_R2 4 SQSPVHLR 8 0 Q96T58;A0A669KB49 Q96T58 SPEN Msx2-interacting protein 1 S(0.009)QS(0.991)PVHLR;S(0.008)QS(0.992)PVHLR;S(0.014)QS(0.986)PVHLR;S(0.001)QS(0.999)PVHLR 97.734 0.003243 62961500.0 42282.8 37043.0 63838.6 88721.0 69905.6 57408.2 45074.2 70516.2 52015.4 51157.8 True False 55727.85086312448 49016.42533465362 62992.05845259977 68267.7441757859 60200.414098490226 53818.45617874079 49085.716479704395 59619.54159107261 54764.827852456234 49366.78099322245 1.1288532438599823 0.9929030078218605 1.276000929881329 1.3828680501805124 1.2194518841881776 1.090175520784503 0.994306606429197 1.2076854190524953 1.1093457331150451 1.0 15.591252955426091 -6.767360537280677 24.24150814786817 1.0879082048146107 1.2028890805002135 0.22992700372743724 0.10903575502530187 179.7248961350497 735795.7925102373 0.04189325203942751 0.03793367887000205 1.7085963045828785e-07 6.767360537280677 0.11498087568560278 SQS(ph)PVHLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SQSPVHLR 8 0 Q96T58;A0A669KB49 Q96T58 SPEN Msx2-interacting protein 1 SQS(1)PVHLR;S(0.006)QS(0.994)PVHLR;SQS(1)PVHLR;S(0.102)QS(0.898)PVHLR 105.2 0.0021795 99621000.0 92442.0 94620.0 122652.0 138121.0 146596.0 125870.0 122766.0 122863.0 103992.0 92123.0 True False 108090.60478727512 104013.24827820473 125576.48884030027 130382.528164324 117871.56614819096 119269.15561852888 111136.71573112927 119637.97643410914 105512.68626646443 108824.17065473313 0.9932591641815917 0.9557917846046167 1.1539393140768082 1.198102658443308 1.0831377389694294 1.0959803773458987 1.0212502889981414 1.099369521626634 0.9695703227661154 1.0 16.731639499875165 -8.26415791333844 24.744645898244954 0.9847851514605998 1.077023157420391 0.21783273808095427 0.0683809294468602 350.9307697583661 3194133.508204543 0.06199157507353156 0.01890204899720593 5.443047028226516e-09 8.26415791333844 0.09223800595979126 SQS(ph)PVHLR ddPTM_PC-9_Lapatinib_30min_R1 3 SQSPVHLR 8 0 Q96T58;A0A669KB49 Q96T58 SPEN Msx2-interacting protein 1 S(0.001)QS(0.999)PVHLR;S(0.05)QS(0.95)PVHLR;S(0.013)QS(0.987)PVHLR 88.155 0.0063403 105959200.0 115392.0 92089.0 119826.0 95154.0 99402.0 100140.0 83446.0 96592.0 112632.0 83234.0 True False 113746.48891969876 91875.77357843144 109974.36882173597 102151.94258443882 93555.36979185125 95857.24563774146 87766.4255755862 101080.01694643233 99946.19809245926 97620.88599766657 1.1651859922928547 0.9411487371731859 1.1265454897056013 1.0464148275286147 0.9583540329073381 0.9819337804415413 0.8990537698836709 1.0354343326575466 1.02381982166038 1.0 16.574902225100338 -6.135579296770336 5.084187178892599 0.9809041180874929 1.0671510733435072 0.3064838836290661 0.06441369253703759 0.2997766009638791 11.165565385908831 0.01866560472316341 0.024422390147403886 7.318476847158224e-07 6.135579296770336 0.08624695525601433 SQS(ph)SDLLER ddPTM_PC-9_AZD4547_30min_R2 4 SQSSDLLER 9 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 S(0.005)QS(0.91)S(0.084)DLLER;S(0.003)QS(0.984)S(0.014)DLLER;S(0.194)QS(0.779)S(0.027)DLLER;S(0.107)QS(0.81)S(0.083)DLLER 104.81 0.0026785 53031000.0 130346.0 130054.0 197194.0 268489.0 251662.0 222506.0 204947.0 301068.0 244936.0 232702.0 True False 171793.31663477432 172091.41215541528 194579.07871572927 206593.00916369935 216723.07530232516 208592.6646455888 223186.88596505258 254544.8584543842 257882.8169132455 224555.17380897581 0.7650383365511549 0.7663658299933436 0.8665089982796541 0.9200100165113252 0.9651217187571316 0.9289149793673159 0.9939066741562267 1.133551519373675 1.1484162780084541 1.0 17.776710437002137 -6.052725392495212 0.5087132323997642 1.0964906543662543 0.7058152723298378 0.8130019222836479 0.05365458668853418 0.6310036099806035 0.2922764273535279 0.04536657904727466 0.1285741002791191 8.856754517341734e-07 6.052725392495212 -0.3906753820364165 SQS(ph)SDLLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SQSSDLLER 9 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 S(0.056)QS(0.909)S(0.035)DLLER;S(0.016)QS(0.911)S(0.073)DLLER;S(0.344)QS(0.613)S(0.043)DLLER 93.649 0.006093199999999999 27666000.0 87894.0 82199.0 102607.0 115119.0 128871.0 110342.0 109871.0 140440.0 113187.0 78176.0 True False 102772.71821436966 90359.17348573402 105053.5400192145 108669.25565083385 103619.652658214 104555.47127401055 99463.22348284471 136753.5988084801 114842.14574623351 92348.6899591243 1.1128768395075153 0.9784564732399464 1.1375747730229164 1.1767276362981804 1.1220478894078356 1.1321814236919794 1.077039896579686 1.480839618504718 1.2435709244718613 1.0 16.49480387510605 SQS(ph)SDLLER ddPTM_PC-9_Lapatinib_30min_R1 4 SQSSDLLER 9 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 S(0.078)QS(0.878)S(0.044)DLLER;S(0.024)QS(0.909)S(0.067)DLLER;S(0.01)QS(0.944)S(0.046)DLLER;S(0.008)QS(0.549)S(0.444)DLLER 94.68799999999999 0.0056671000000000004 42300100.0 189800.0 168719.0 192105.0 185962.0 206034.0 165016.0 163872.0 165415.0 217711.0 294994.0 True False 187093.41719494257 168328.3415215647 176310.86844674428 199638.2658310469 193915.48519842938 157958.65035108387 172356.49032814585 173100.7847771468 193190.0945815346 345983.31984520255 0.5407584888157342 0.4865215513767455 0.5095935507111385 0.5770170247524293 0.5604763989350403 0.45654990079220187 0.4981641612239006 0.5003154049582342 0.5583797931876322 1.0 18.40034296040089 -8.835387381540805 3.2424688908302794 0.9999964682880778 0.5162063610008624 0.9482747363217336 0.0336967751022448 0.8947446970155843 9.084263919294985 0.03493947296555323 0.009240197396335479 1.4608735246801378e-09 8.835387381540805 -0.4837901072872154 SQS(ph)SDTEQQS(ph)PTSGGGK ddPTM_PC-9_AZD4547_30min_R2 1 SQSSDTEQQSPTSGGGK 17 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 S(0.002)QS(0.757)S(0.24)DT(0.002)EQQS(0.8)PT(0.186)S(0.013)GGGK 187.52 1.1325999999999997e-41 0.0 8763.5 6306.1 9264.5 11574.0 11791.0 9778.0 9113.1 9615.7 8832.0 9598.6 True False 11550.110707876282 8344.4235024933 9141.646676683238 8905.79311651746 10154.023177475035 9166.580114264641 9924.148245586039 8129.814511804047 9298.841489114635 9262.555935586463 1.2469679846683681 0.9008769890861631 0.9869464476388538 0.9614833290562564 1.0962441952402773 0.9896383004875485 1.0714265387005932 0.8777074673924011 1.003917445009834 1.0 13.1771946343882 -4.749067466993315 24.98948467079857 0.9890052664196373 1.246968582775641 0.6048184106086059 0.06289087806092843 404.52625478578057 817035.344119639 0.015516214799108483 0.26437562841786777 1.7821018990985716e-05 4.749067466993315 0.25796331635600367 SQS(ph)SDTEQQSPTSGGGK ddPTM_PC-9_AZD4547_30min_R2 2 SQSSDTEQQSPTSGGGK 17 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 S(0.007)QS(0.991)S(0.003)DTEQQSPTSGGGK;S(0.003)QS(0.498)S(0.498)DTEQQSPTSGGGK 255.72 1.1829999999999998e-57 30687600.0 29217.3 31835.5 42671.0 53148.0 42834.0 36093.0 32509.0 41678.0 31855.0 38734.0 True False 38507.79364240699 42125.70279786638 42105.15465926389 40895.54972841456 36887.2384686596 33836.0990043111 35402.23802172218 35237.62276516208 33538.79026672857 37377.934449712026 1.0302279729826984 1.1270206183956464 1.1264708785851136 1.0941094078763263 0.9868720412650783 0.9052426117830005 0.9471427071325215 0.9427386313326247 0.8972884874591288 1.0 15.189899225746117 -6.373021273805543 3.1140003697031777 0.9358708185644199 1.1002794262775053 0.8031314243166356 0.03641222230776786 0.10391317996793586 1.9204174357152162 0.011636255928219881 0.013479892631717158 4.236222145140712e-07 6.373021273805543 0.1644086077130854 SQS(ph)SDTEQQSPTSGGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SQSSDTEQQSPTSGGGK 17 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 S(0.001)QS(0.903)S(0.096)DTEQQSPTSGGGK;S(0.014)QS(0.9)S(0.086)DTEQQSPTSGGGK;SQS(0.766)S(0.226)DT(0.006)EQQS(0.001)PTSGGGK;SQS(0.975)S(0.025)DTEQQSPTSGGGK;SQS(0.916)S(0.084)DTEQQSPTSGGGK 308.24 1.769399999999999e-277 25964800.0 65701.5 75542.7 72957.1 93731.3 98496.70000000001 96614.1 82673.0 98242.2 79973.90000000001 74270.1 True False 76823.46628622421 83042.08001168819 74696.6739553427 88479.83914197446 79196.97869947711 91547.4865165974 74841.61493931287 95663.4463462152 81143.36699174573 87734.681208212 0.8756339594362543 0.9465137260214427 0.851392777937752 1.0084933110088363 0.9026872567249294 1.0434583594067761 0.8530448154441765 1.0903720744044951 0.9248721927783181 1.0 16.420859627197615 -4.915346779982278 0.3262481874118624 0.9967838394215894 0.8097485108070493 0.1739959368720504 0.07150214812043272 11.112627836441257 1.0241135250745903 0.07006627373565948 0.8231174907321682 1.2152152753876444e-05 4.915346779982278 -0.1870353286145401 SQS(ph)SHSYDDSTLPLIDR ddPTM_PC-9_AZD4547_30min_R2 1 SQSSHSYDDSTLPLIDR 17 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;H0YC95 O60716 CTNND1 Catenin delta-1 1 S(0.086)QS(0.744)S(0.169)HS(0.001)YDDSTLPLIDR 172.95 7.7104e-06 4182900.0 0.0 5466.5 7159.3 12900.0 10300.0 6959.2 5299.9 10033.0 6214.2 7385.2 True False 0.0 7233.4392217661625 7064.363004196478 9926.104303013244 8870.022790941639 6524.040123868943 5771.5808327332525 8482.630385404083 6542.669925459264 7126.6463958799295 0.0 1.0149850041595962 0.9912604908082069 1.3928156038093518 1.244627879400554 0.9154432199190679 0.8098592959614118 1.190269576207412 0.9180573248648516 1.0 12.799007628340613 -4.768630327615692 6.5768783319194775 1.0638683064513712 8.318761357734863e-17 0.7840596208005078 0.16582140840977402 0.052477336760642486 10.935271253423274 0.04403438171951446 0.24809481822935375 1.7036080061485173e-05 4.768630327615692 -1.0638683064513712 SQS(ph)SHSYDDSTLPLIDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSSHSYDDSTLPLIDR 17 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;H0YC95 O60716 CTNND1 Catenin delta-1 1 S(0.001)QS(0.444)S(0.444)HS(0.052)Y(0.001)DDS(0.002)T(0.056)LPLIDR 165.17 2.6891e-05 3848100.0 1793.5 3910.8 4755.6 4471.3 7665.9 6785.4 3809.5 4955.8 3670.4 4725.9 True False 2097.104126760322 4299.038378423208 4868.991539713431 4220.787557150188 6163.821925123598 6429.561678985983 3448.636581608407 4825.7155011041405 3724.0726562854047 5582.668259796186 0.3756454851280888 0.770068751780024 0.8721620761128998 0.7560520096718557 1.1040996237431147 1.1517004736406664 0.6177398371391516 0.86441022044185 0.6670775484018039 1.0 12.446739113721987 -4.59622931592272 1.8180467296760023 0.8808201275138818 7.564874282270867e-13 0.458817698899602 0.16385615649036575 1.480737448389819 3.3710904304874716 0.04633720163079335 2.622062100759168 2.533790386675978e-05 4.59622931592272 -0.8808201275131253 SQS(ph)SHSYDDSTLPLIDR ddPTM_PC-9_Lapatinib_30min_R1 1 SQSSHSYDDSTLPLIDR 17 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;H0YC95 O60716 CTNND1 Catenin delta-1 1 S(0.001)QS(0.428)S(0.428)HS(0.142)YDDS(0.001)TLPLIDR 145.91 9.5686e-05 2854800.0 7639.8 10310.0 5418.8 5395.9 5884.8 5109.0 2711.6 3215.6 7094.1 3190.0 True False 7530.855051032264 10286.127828444514 4973.287181172896 5792.732486194728 5538.667633961952 4890.49997966069 2851.9933800393014 3365.008515124942 6295.087753815216 3741.3872495921833 2.0128509958046013 2.7492817883435396 1.3292628774834767 1.5482846601420754 1.4803780695424336 1.3071354696560111 0.7622823273239553 0.8994012890517368 1.6825544467500364 1.0 11.869357583390224 -5.496575109027334 1.0522648800891956 1.1437572856828089 2.4872710015928488 0.5847565195593677 0.35738211667949443 0.5025841036434487 0.91665452453283 0.12799853274662712 0.5831954474981144 3.1873142981893186e-06 5.496575109027334 1.3435137159100399 SQS(ph)SSQFR ddPTM_PC-9_AZD4547_30min_R2 1 SQSSSQFR 8 0 Q16537-2;Q16537 Q16537-2 PPP2R5E Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform 1 SQS(0.69)S(0.249)S(0.061)QFR 114.97 0.0036543 144310000.0 251470.0 242210.0 247740.0 487520.0 305420.0 314520.0 238250.0 252090.0 235720.0 364560.0 True False 331432.22909906437 320499.6458252966 244454.8057295594 375129.7961089157 263017.70493295067 294853.01467974205 259453.7884485935 213135.28295191017 248179.67796808248 351796.8653634279 0.9421125135855727 0.9110361045832533 0.6948748832000605 1.0663250103760402 0.7476408428518462 0.8381342863164533 0.7375102338690872 0.605847589721211 0.7054630168796346 1.0 18.424383102372367 -6.758589860850621 1.7285803298629943 0.7361597675220987 0.8861614328198268 0.134432291772546 0.13256913450279095 0.5916204966917978 3.6577872436506143 0.05437547231080468 0.04971795848882927 1.7434525784376893e-07 6.758589860850621 0.15000166529772818 SQS(ph)SSQFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSSSQFR 8 0 Q16537-2;Q16537 Q16537-2 PPP2R5E Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform 1 S(0.002)QS(0.479)S(0.479)S(0.04)QFR 109.83 0.0037717 102370000.0 196450.0 297950.0 257950.0 334330.0 254230.0 298630.0 265850.0 287110.0 219940.0 225940.0 True False 229705.1049356369 327528.50691704924 264100.50628082245 315598.57401248504 204415.45650532492 282969.3170919306 240666.76341267792 279573.6667181905 223156.206414399 266901.13345994346 0.860637427641764 1.2271529261459833 0.9895068741641694 1.182454978445605 0.7658845575341238 1.0602027553187543 0.9017075360183782 1.047480252683711 0.8361006321761848 1.0 18.02594590668165 -6.242177247186338 24.99980161098075 0.9421758647107409 1.071136871287235 0.19970331314130085 0.12650592455903698 1319.019916925281 1711919.883854431 0.03443601493217858 0.04438607553049472 5.72562305313389e-07 6.242177247186338 0.128961006576494 SQS(ph)SSQFR ddPTM_PC-9_Lapatinib_30min_R1 3 SQSSSQFR 8 0 Q16537-2;Q16537 Q16537-2 PPP2R5E Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform 1 S(0.001)QS(0.454)S(0.454)S(0.091)QFR;S(0.002)QS(0.478)S(0.478)S(0.042)QFR;S(0.072)QS(0.824)S(0.072)S(0.032)QFR 110.53 0.0037604 285635000.0 675719.0 555497.0 656097.0 600543.0 583135.0 598585.0 598969.0 459782.0 698217.0 487751.0 True False 666083.1231483113 554210.7808261337 602155.2372676601 644708.9355727207 548836.1457875205 572984.9149197879 629980.6840421748 481145.1502367123 619576.4489090372 572058.1104626459 1.16436269491857 0.9688015442660565 1.0526120096097815 1.1269990299609933 0.9594062836442526 1.0016201229214152 1.1012529540621052 0.8410774035658568 1.0830655794880022 1.0 19.12580217986367 -6.272655312171963 24.753697097025686 0.9951608762785529 1.0685528158947672 0.18445991558669173 0.08177281669228273 1195.473047884307 2638419.428571275 0.024425979399986128 0.027963719407309913 5.33758357046019e-07 6.272655312171963 0.07339193961621437 SQS(ph)TFQLSSEPEREPEWR ddPTM_PC-9_Lapatinib_30min_R1 1 SQSTFQLSSEPEREPEWR 18 1 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 S(0.185)QS(0.688)T(0.127)FQLSSEPEREPEWR 63.681000000000004 0.008204099999999999 2798200.0 5157.4 3501.5 4916.9 3023.3 4518.6 5001.8 5201.8 3289.0 3605.5 2513.8 True False 5083.854530248672 3493.3924918815205 4512.651461782872 3245.643567433147 4252.824831909405 4787.884673765284 5471.12375139712 3441.8189470848165 3199.410622401821 2948.3069805720506 1.7243301202177623 1.1848808536225452 1.530590773457144 1.1008499416174786 1.4424633730250989 1.6239437430753245 1.855683206480614 1.1673882569775726 1.0851687573527535 1.0 11.52567103171774 -7.97986094564722 24.893849206184395 1.0704822484697136 1.4747867311649827 0.43746271137092263 0.21513212546163873 218.13477510920225 269635.8397024755 0.12167390159917525 0.058440334958222345 1.0474638760409146e-08 7.97986094564722 0.4043044826952691 SQS(ph)TTFNPDDMSEPEFK ddPTM_PC-9_AZD4547_30min_R2 1 SQSTTFNPDDMSEPEFK 17 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.106)QS(0.658)T(0.162)T(0.072)FNPDDMS(0.002)EPEFK 62.203 0.026077999999999997 24474000.0 16023.0 22191.0 18896.0 29290.0 30443.0 29815.0 30125.0 39155.0 32311.0 28634.0 True False 21117.980700895936 29363.80678134326 18645.42669357293 22537.643025988993 26216.514934430706 27950.66333675602 32806.066640142126 33104.4944423898 34018.89349578613 27631.532375511277 0.7642710658932531 1.0626919413042482 0.6747880081416557 0.8156494080640713 0.9487897586767702 1.0115495209208005 1.187269174735196 1.198069437210402 1.231162030157101 1.0 14.75402795216849 -6.8636869857327865 1.7652880230861623 1.1711882571696228 0.8391506643113602 0.6266613604000582 0.11076410788664548 0.22398999527832314 1.4351303661019879 0.047744917351599074 0.04036153758970828 1.368714960517076e-07 6.8636869857327865 -0.3320375928582626 SQS(ph)TTFNPDDMSEPEFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSTTFNPDDMSEPEFK 17 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.02)QS(0.441)T(0.127)T(0.043)FNPDDMS(0.369)EPEFK 65.949 0.018311 14834000.0 51829.0 58687.0 59096.0 61532.0 77294.0 56773.0 55227.0 64958.0 45671.0 49599.0 True False 60602.62603058866 64513.05751112885 60505.07276282803 58084.56152943558 62148.795559621656 53795.72393684548 49995.49875114511 63252.92132869015 46338.85197395674 58590.906074532046 1.0343350204125117 1.1010762903899007 1.0326700304969003 0.9913579669778044 1.0607242612115215 0.9181582525522523 0.8532979279676451 1.079568922320943 0.7908881271610688 1.0 15.838389140113616 -6.763429367046011 24.988158145613514 0.9286628940640946 1.043644174570376 0.36107792658765236 0.0769186894219206 58.51561434705534 734768.4187140353 0.025097766753158973 0.023245370338780245 1.724132478350604e-07 6.763429367046011 0.11498128050628131 SQS(ph)TTFNPDDMSEPEFKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSTTFNPDDMSEPEFKR 18 1 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.079)QS(0.833)T(0.079)T(0.009)FNPDDMSEPEFKR 68.705 0.0043641999999999995 20403000.0 71038.0 67489.0 102870.0 93277.0 115490.0 119010.0 92514.0 109640.0 115720.0 76352.0 True False 83063.33033554499 74188.8619007373 105322.8109366474 88050.99209811416 92860.56355190206 112768.90609486862 83750.4041766428 106762.06617318238 117412.18607926821 90194.01319790052 0.9209406188999525 0.8225475202877903 1.167736163436389 0.9762398742022464 1.0295646047831433 1.2502925870194408 0.9285583511278139 1.1836934890448751 1.301773609093616 1.0 16.460744054534025 -4.881292078814884 0.5720309920301806 1.135009915283855 0.7077539951710539 0.29615125855980406 0.12614472449538436 4.3456338809006585 1.1718890958788648 0.06873955569069896 1.2175484962321572 1.3143405930916618e-05 4.881292078814884 -0.4272559201128012 SQS(ph)TTFNPDDMSEPEFKR ddPTM_PC-9_Lapatinib_30min_R1 2 SQSTTFNPDDMSEPEFKR 18 1 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.187)QS(0.689)T(0.055)T(0.069)FNPDDMSEPEFKR;S(0.069)QS(0.852)T(0.069)T(0.009)FNPDDMSEPEFKR 89.62200000000001 0.00065175 19821900.0 54253.0 32407.0 39067.0 43514.0 42465.0 33326.0 25964.5 27805.0 40084.0 29370.0 True False 53479.34227121831 32331.963582580152 35855.06206298105 46714.16471844874 39967.29218940221 31900.72466670037 27308.814764725794 29096.921807142975 35569.31781676732 34446.56536693493 1.5525304686124917 0.938612115262308 1.0408893217957262 1.3561341811828187 1.1602692972044928 0.9260930466327916 0.7927877416463524 0.8446973304070818 1.0325940318830775 1.0 15.072072519950206 -6.754269038994705 4.616128171557378 0.8988752422297644 1.1963368083027104 0.4234575809300374 0.1689816621529991 0.19782992358272528 10.509057910103678 0.058917089918635486 0.05550992651549671 1.7608848663855775e-07 6.754269038994705 0.29746156607294594 SQS(ph)TTSDVPANYK ddPTM_PC-9_AZD4547_30min_R2 1 SQSTTSDVPANYK 13 0 Q9NU19 Q9NU19 TBC1D22B TBC1 domain family member 22B 1 SQS(0.81)T(0.189)T(0.001)SDVPANYK 182.57 6.7269e-05 6280500.0 18100.0 26901.0 30832.0 49294.0 36922.0 28298.0 29522.0 53771.0 39328.0 32831.0 True False 23855.42349661217 35596.22217227321 30423.147534729083 37930.029884708136 31796.01762011137 26528.521586567917 32149.40080830794 45461.92748465692 41406.79779029672 31681.596682978645 0.7529741551639918 1.1235614962360072 0.9602782283720669 1.197225956262695 1.0036115899800657 0.8373479989668802 1.0147658001586968 1.4349632671475152 1.3069668869480642 1.0 14.951357425464694 -7.673995266652611 8.104688026437563 1.2772512514155265 0.9906500249916452 0.3686444165781144 0.15630593621590852 0.23642697661415693 19.102274962802955 0.07216774758793501 0.04141937707403039 2.1183842232549318e-08 7.673995266652611 -0.2866012264238813 SQS(ph)WDDRGER ddPTM_PC-9_Lapatinib_30min_R1 1 SQSWDDRGER 10 1 O75420 O75420 GIGYF1 PERQ amino acid-rich with GYF domain-containing protein 1 1 S(0.059)QS(0.941)WDDRGER 53.869 0.045824000000000004 9529600.0 25244.0 25423.0 23858.0 16790.0 29073.0 19849.0 21470.0 26275.0 31794.0 25141.0 True False 24884.01593081737 25364.13460548447 21896.48733454327 18024.792609798096 27362.983299717194 19000.10454027892 22581.611546483175 27495.832421603372 28213.02491433741 29486.588351723236 0.8439096322027745 0.8601922441123018 0.7425914138779508 0.6112878300735901 0.9279806457540912 0.644364289067322 0.7658265268644914 0.9324860541214995 0.956808721911316 1.0 14.847771289342141 -7.81723985043052 4.2661901289692 0.9670687175004031 0.7677823923763967 0.48976920783668154 0.09041582952965392 0.18852373883080353 6.9403626375198915 0.052325434530460055 0.02451903054149594 1.5232112883811948e-08 7.81723985043052 -0.19928632512400646 SQS(ph)WEER ddPTM_PC-9_AZD4547_30min_R2 2 SQSWEER 7 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 S(0.371)QS(0.629)WEER;S(0.294)QS(0.706)WEER 79.20100000000001 0.027214 426550000.0 62138.0 66812.0 87970.0 101223.0 92749.0 75834.0 90517.0 111760.0 89174.0 88349.0 True False 81896.59144930853 88407.67242013013 86803.460321423 77887.60122976034 79872.40231427639 71092.08799193552 98572.83764533598 94490.05998931138 93887.55558767088 85255.9284013426 0.9605970280891204 1.0369680335184515 1.018151604810347 0.913574019898114 0.9368545250985569 0.8338667975940542 1.1561992168017219 1.108310727020637 1.1012437181575794 1.0 16.379512537180005 -7.278175048498478 24.999106186296697 1.1004643116906025 0.954799276308572 0.5387498221663216 0.0638017899204973 672.2607631180229 1004193.3578034646 0.02792291159056426 0.01888230648509668 5.27017396833962e-08 7.278175048498478 -0.14566503538203057 SQS(ph)WEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQSWEER 7 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 S(0.002)QS(0.998)WEER;S(0.027)QS(0.973)WEER 88.134 0.017475 173757800.0 103478.0 111956.0 102223.0 115640.0 132751.0 98405.0 159918.0 138714.0 112992.0 109379.0 True False 120994.78161633914 123070.25178857226 104660.38400288619 109161.06570993828 106739.39451102716 93244.46856789805 144769.40933394243 135072.9044796321 114644.29424013763 129208.5468563122 0.9364301709150303 0.9524931189376652 0.8100113076828805 0.8448440011583139 0.8261016558736466 0.7216586737995869 1.1204321452119947 1.0453867624549746 0.8872810431621764 1.0 16.979341978674455 -7.266762731521461 24.990834288969605 1.0170572134967635 0.8503666760734512 0.4990121962197366 0.08079114923398141 402.82545431073555 1891081.9867121358 0.034855023373329755 0.024270566775855148 5.4104983443698865e-08 7.266762731521461 -0.1666905374233123 SQS(ph)WEER ddPTM_PC-9_Lapatinib_30min_R1 1 SQSWEER 7 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 S(0.056)QS(0.944)WEER 70.942 0.04269 220560000.0 34111.0 30786.0 29500.0 31152.0 37947.0 28285.0 33393.0 32749.0 41569.0 33465.0 True False 33624.57088480872 30714.71690848621 27074.623873293065 33443.022000025616 35715.032066672444 27075.31648555541 35121.92614679612 34270.63809610233 36887.06147902408 39249.380660690425 0.8566904832331498 0.782552906350648 0.6898102191051695 0.8520649609515986 0.9099514811565486 0.689827865555908 0.8948402638610782 0.8731510540859445 0.9398125743157958 1.0 15.260382268590652 -8.113239132589385 0.9476117056827731 0.9984682767650619 0.7975827435464061 0.48188882305192005 0.06926862284154141 0.4698931564939649 0.8284104863957253 0.06566887577778634 0.02406901940606844 7.704791086211352e-09 8.113239132589385 -0.20088553321865577 SQS(ph)WEERGDR ddPTM_PC-9_AZD4547_30min_R2 2 SQSWEERGDR 10 1 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 SQS(1)WEERGDR;S(0.001)QS(0.999)WEERGDR 99.5 0.020993 78180000.0 52449.0 49705.0 72084.0 116680.0 77691.0 60536.0 64887.0 94524.0 69004.0 80948.0 True False 69126.69099302831 65771.16921574813 71128.11906115114 89781.22868802989 66904.94569427647 56750.67435028884 70661.81729722487 79917.48774543348 72651.41056554206 78114.03515865363 0.8849458468331388 0.8419891391113453 0.9105677221345213 1.149361039993384 0.8565035151287356 0.7265105974236935 0.9045982217370679 1.0230874334313538 0.9300685903369772 1.0 16.25329416779642 -7.682812710070373 7.9629715443889015 0.9821388815789465 0.8961067923965286 0.13717682100120476 0.10123081412022573 0.5646562010149576 49.645920983828944 0.0523202698430825 0.029996947694670095 2.0758085189555555e-08 7.682812710070373 -0.08603208918241789 SQS(ph)YIPTSGCR ddPTM_PC-9_AZD4547_30min_R2 1 SQSYIPTSGCR 11 0 A0A087WZ32;A0A087X038;A8K727;Q9HB19;E5RHB5 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 S(0.197)QS(0.67)YIPT(0.133)SGCR 155.14 0.00061064 47156000.0 53971.0 47218.0 80874.0 95243.0 64094.0 63532.0 64825.0 78317.0 58890.0 64822.0 True False 71132.65533346163 62480.29510168385 79801.55791786712 73286.19783968134 55195.65444297216 59559.3339966723 70594.2994173349 66214.90719562357 62002.80517368217 62552.60151028121 1.137165419439353 0.9988440703207927 1.2757512236281787 1.1715931243504867 0.8823878321655438 0.9521479931875106 1.1285589681786767 1.0585476158771818 0.9912106559387674 1.0 15.932782265666116 -6.228799162431439 24.902231599233872 1.0088906562893574 1.1446183647490846 0.3945123842011975 0.08696540172981433 745.662320766218 568888.4833933074 0.027336110541238 0.03528836964943447 5.904740791781852e-07 6.228799162431439 0.13572770845972726 SQS(ph)YIPTSGCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQSYIPTSGCR 11 0 A0A087WZ32;A0A087X038;A8K727;Q9HB19;E5RHB5 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 SQS(0.951)YIPT(0.043)S(0.006)GCR;S(0.121)QS(0.683)Y(0.001)IPT(0.19)S(0.005)GCR 113.53 0.0015522 73690900.0 61678.0 75135.0 61712.0 72374.0 78128.0 64418.0 73578.0 75510.0 52900.0 52011.0 True False 72118.86720397166 82593.90625008357 63183.44812406329 68319.119419674 62819.379246540746 61039.80667859212 66608.15918141056 73527.94250945821 53673.56242303232 61440.18258115056 1.1738061993666218 1.344297864691288 1.0283733782953886 1.111961529890275 1.0224477956843394 0.9934834844927483 1.0841139525168908 1.1967402995969627 0.8735905423480791 1.0 15.906894882856713 -5.272649030433561 24.94733636833372 1.0478885647791611 1.2590520327303543 0.494109571483622 0.08875205922031762 498.9199849200325 1110358.681852882 0.022201646512109457 0.04689210481688081 5.337660775093397e-06 5.272649030433561 0.21116346795119312 SQS(ph)YIPTSGCR ddPTM_PC-9_Lapatinib_30min_R1 1 SQSYIPTSGCR 11 0 A0A087WZ32;A0A087X038;A8K727;Q9HB19;E5RHB5 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 S(0.036)QS(0.927)Y(0.001)IPT(0.035)SGCR 110.44 0.0019364 142520000.0 61347.0 54901.0 63001.0 59684.0 66019.0 62237.0 63810.0 57765.0 60368.0 48551.0 True False 60472.180530337995 54773.88010760737 57821.30097089278 64073.360459987416 62135.89221834799 59575.26859153304 67113.76957527208 60448.97278150026 53568.720136778014 56942.97565985902 1.0619778792657446 0.9619075833829192 1.0154246472168984 1.1252197433924207 1.091195033247088 1.046226824312759 1.1786136709146864 1.061570318042103 0.9407432526316037 1.0 15.79723026528069 -4.405006718733517 21.860349105166534 1.0530835101505052 4.4182957549414725 0.0 0.06906693690791545 11014.811720976279 2253213.2129317485 0.017401763005761073 191679.91832258154 3.935439871038876e-05 4.405006718733517 3.3652122447909676 SQSAAVT(ph)PSSTTSSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSAAVTPSSTTSSTR 16 0 Q16186;A0A087WX59 Q16186 ADRM1 Proteasomal ubiquitin receptor ADRM1 1 SQS(0.001)AAVT(0.924)PS(0.067)S(0.008)T(0.001)TSSTR 198.98 2.0885e-50 0.0 16095.0 17464.0 19470.0 16142.0 21423.0 19296.0 16428.0 15376.0 14937.0 13658.0 True False 18819.56560925975 19197.710504444844 19934.238640386182 15237.616073070107 17225.316936292267 18284.083791333374 14871.820911579709 14972.396292218653 15155.425366972295 16134.087283331493 1.1664474896390753 1.1898851275137485 1.2355355645671209 0.9444361993016145 1.0676350408794522 1.1332580188916601 0.9217640050171377 0.9279977248968393 0.9393419721132736 1.0 13.977824345409257 -6.0877631579405405 0.5845784046581735 0.9448553363613911 1.2296148702598948 0.5652852399142128 0.07573477188075316 0.8686650769444082 0.5718644521812399 0.05535884897286636 0.13939098834830219 8.170278151846921e-07 6.0877631579405405 0.2847595338985037 SQSAAVT(ph)PSSTTSSTR ddPTM_PC-9_Lapatinib_30min_R1 2 SQSAAVTPSSTTSSTR 16 0 Q16186;A0A087WX59 Q16186 ADRM1 Proteasomal ubiquitin receptor ADRM1 1 SQS(0.005)AAVT(0.439)PS(0.439)S(0.104)T(0.006)T(0.006)SSTR;SQS(0.002)AAVT(0.731)PS(0.062)S(0.018)T(0.034)T(0.118)S(0.034)S(0.001)TR 209.23 7.436e-17 51416000.0 64182.0 59100.0 66409.0 62858.0 66316.0 56284.0 53374.0 47193.0 67470.0 55896.0 True False 63266.75291046269 58963.15758109317 60949.108366153254 67480.78700814102 62415.42326227241 53876.86452441225 56137.44455901225 49385.75906651675 59870.81810940257 65557.54912326178 0.9650567136289382 0.899410645602846 0.929703888892434 1.0293366349200022 0.952070724073569 0.8218254837915399 0.8563078594268712 0.7533191787518061 0.9132558936398465 1.0 16.000474299670017 -6.749155086706924 24.171304907190827 0.8527345235592194 0.9547326532690718 0.2746126731347447 0.06750399869180941 168.2227617787466 331004.0372723059 0.021735471955935805 0.02156895453557045 1.7817423930166675e-07 6.749155086706924 0.10199812970985234 SQSAAVTPS(ph)STTSSTR ddPTM_PC-9_AZD4547_30min_R2 2 SQSAAVTPSSTTSSTR 16 0 Q16186;A0A087WX59 Q16186 ADRM1 Proteasomal ubiquitin receptor ADRM1 1 SQSAAVT(0.202)PS(0.65)S(0.07)T(0.021)T(0.021)S(0.036)S(0.001)TR;SQS(0.005)AAVT(0.127)PS(0.781)S(0.08)T(0.004)TSS(0.001)TR 225.17 1.2613999999999999e-28 44357000.0 26511.8 26294.2 35377.0 49075.0 43555.0 40688.0 24415.3 50026.0 32958.0 38819.0 True False 34942.000920302875 34793.285938893976 34907.87786507883 37761.516951191865 37508.140064025516 38143.77292791983 26588.214401296664 42295.63118311814 34700.092594909445 37459.95862558402 0.9327826885649186 0.9288127167105629 0.9318717677717296 1.0080501510592137 1.001286211736726 1.0182545397118723 0.7097769292018843 1.1290891056732641 0.926324904459727 1.0 15.193061685678787 -10.926768445722642 0.006310284689026367 1.975211920652787 9.61849018479288e-07 0.018826406709684274 0.10093298035337742 88394.99438823086 92.21032634108175 15066.430531074848 13814.585288966224 1.1836724902298356e-11 10.926768445722642 -1.9752109588037685 SQSAAVTPS(ph)STTSSTR ddPTM_PC-9_Lapatinib_30min_R1 1 SQSAAVTPSSTTSSTR 16 0 Q16186;A0A087WX59 Q16186 ADRM1 Proteasomal ubiquitin receptor ADRM1 1 SQS(0.074)AAVT(0.056)PS(0.784)S(0.036)T(0.012)T(0.036)S(0.002)STR 145.82 2.9704000000000002e-05 19614000.0 16947.0 11980.0 18046.0 17026.0 13736.0 14702.0 13234.0 8963.0 14359.0 11701.0 True False 16705.33267230083 11952.261046049001 16562.32753957447 18278.148837070996 12928.07548601505 14073.229732035914 13919.191765540689 9379.453701040191 12741.738213026694 13723.502259397541 1.2172791140731878 0.8709337325218397 1.2068586594382618 1.3318866052981875 0.9420390831474669 1.025483835396237 1.0142594435767402 0.6834591872943625 0.9284611152595135 1.0 13.744361086095333 -7.037658737880661 1.3745513587085016 0.8686616877600373 1.126487309256803 0.32745665271970303 0.14703747337566803 0.49724090912901514 1.9001164506860253 0.08095237000051675 0.05737196385664603 9.169407254408805e-08 7.037658737880661 0.2578256214967658 SQSAAVTPSS(ph)TTSSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSAAVTPSSTTSSTR 16 0 Q16186;A0A087WX59 Q16186 ADRM1 Proteasomal ubiquitin receptor ADRM1 1 SQS(0.034)AAVT(0.125)PS(0.192)S(0.486)T(0.145)T(0.017)SSTR 195.45 8.314e-12 21233000.0 28352.0 34385.0 37630.0 31889.0 38697.0 32970.0 36745.0 33600.0 29776.0 23265.0 True False 33151.43362247484 37798.515557451654 38527.241912569705 30102.36271553291 31114.60063873881 31240.995159632123 33264.24758923764 32718.03560214275 30211.417669342358 27482.76033436134 1.2062628796797399 1.3753536798191504 1.4018694426556415 1.0953180229824409 1.132149764441115 1.1367488119660203 1.210367779092691 1.1904930656196064 1.09928614527011 1.0 14.746239293483407 -1.5228787452831587 0.09081119483409207 0.8784371145961579 2.1271259461398504 0.4789728504719012 0.08514082817171574 143.0743070809941 0.9367940096010859 1.6671297068636364 22.248688183135574 0.029999999999805124 1.5228787452831587 1.2486888315436926 SQSAAVTPSSTTSSTR ddPTM_PC-9_Lapatinib_30min_R1 2 SQSAAVTPSSTTSSTR 16 0 Q16186;A0A087WX59 Q16186 ADRM1 Proteasomal ubiquitin receptor ADRM1 0 ; 159.41 0.00013775 2942600.0 8339.2 8593.5 10738.599999999999 10325.8 9685.0 10004.2 8200.7 7282.0 9469.7 5868.200000000001 False True 8220.281478778019 8573.602278733066 9855.713760194747 11085.193777859025 9115.347341442615 9576.343686929235 8625.292119666727 7620.348304247988 8403.122665638197 6882.510551115008 1.1943725211501905 1.2457085557746208 1.4319939921629417 1.6106322969694769 1.324421847775573 1.3914026888600715 1.2532188734922285 1.1072047398479392 1.2209385809480293 1.0 12.74871920118356 -7.54104537524448 2.4841775147045095 1.1186844711272181 1.3737597315862768 0.490329495472161 0.11681464784071444 0.28166343693763135 3.482967688232319 0.06983032683968052 0.03721772259800952 2.877097798813531e-08 7.54104537524448 0.2550752604590587 SQSAS(ph)YYPVCHSK ddPTM_PC-9_Lapatinib_30min_R1 1 SQSASYYPVCHSK 13 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 S(0.278)QS(0.278)AS(0.441)Y(0.001)Y(0.001)PVCHS(0.002)K 68.26100000000001 0.018833000000000003 3767000.0 31980.0 26239.0 30708.0 37066.0 27144.0 23096.0 28280.0 27635.0 37660.0 34075.0 True False 31523.959335586256 26178.245207619366 28183.30677630793 39791.95728855129 25547.443287157264 22108.23791940562 29744.20002489727 28919.022986527463 33418.33422261894 39964.818347916516 0.7887927592001602 0.6550322581156963 0.7052029245061541 0.9956746692087933 0.639248327485245 0.5531925036400969 0.7442596076868675 0.7236120213226266 0.836193822568973 1.0 15.286442911317927 -8.5845354236823 2.169454719876618 0.9995910511585415 0.7227396057099247 0.3762753262279036 0.10958941809611901 0.4197324976351941 4.521713335613353 0.10982420523327066 0.03026590824756878 2.602942510994965e-09 8.5845354236823 -0.27685144544861684 SQSDLDDQHDYDS(ph)VASDEDTDQEPLR ddPTM_PC-9_AZD4547_30min_R2 1 SQSDLDDQHDYDSVASDEDTDQEPLR 26 0 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QLH1 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 SQSDLDDQHDY(0.022)DS(0.361)VAS(0.255)DEDT(0.361)DQEPLR 50.70399999999999 0.01119 7704600.0 19400.0 21673.0 27163.0 31422.0 31116.0 25462.0 23480.0 31221.0 29499.0 25044.0 True False 25568.796454932362 28678.373411385357 26802.800872011074 24178.143365060627 26796.080501256318 23869.857114891238 25569.674513212845 26396.51183720728 31058.25691659793 24167.217182800345 1.0579950625481824 1.186664281388408 1.109056151118899 1.0004521075876316 1.1087780731464159 0.987695725756926 1.0580313951666152 1.0922445740254079 1.2851399762609779 1.0 14.560763738142757 -10.899744155198139 4.00034829928587 0.9997089421707713 1.0941498337325508 0.11148045355861047 0.08258294102850156 0.00022611059033649143 3.522128662151876e-05 0.08109547161934356 0.019605650161672882 1.2596672688215485e-11 10.899744155198139 0.09444089156177948 SQSES(ph)SDEVTELDLSHGK ddPTM_PC-9_AZD4547_30min_R2 1 SQSESSDEVTELDLSHGK 18 0 Q86YS7-3;Q86YS7;Q86YS7-2;Q86YS7-4;Q86YS7-5 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 S(0.108)QS(0.434)ES(0.444)S(0.013)DEVTELDLSHGK 177.12 9.5604e-33 0.0 5550.0 8412.2 7339.8 9583.9 8300.3 10409.0 8053.9 10074.0 8956.5 8243.7 True False 7314.784552828589 11131.279140463064 7242.469456259878 7374.479924778958 7147.946618607072 9758.123584514287 8770.681497528323 8517.29477749035 9429.922304942853 7955.090572186999 0.9195099020497539 1.399264915899364 0.9104194842961782 0.9270139488495577 0.8985374275433261 1.2266514750480837 1.1025244047117244 1.070672256990883 1.1853947129039908 1.0 12.957662641026225 -6.767746608954044 24.99089746167261 1.1205577951592338 1.0222741894541183 0.10983536033573982 0.14912644950825107 406.09529006926374 1609045.1239929872 0.05323898715182644 0.048096823157526586 1.7070781008047127e-07 6.767746608954044 -0.09828360570511552 SQSFNTDTTTSGISSMS(ph)SSPSR ddPTM_PC-9_AZD4547_30min_R2 1 SQSFNTDTTTSGISSMSSSPSR 22 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 SQSFNTDTTTSGIS(0.005)S(0.057)MS(0.646)S(0.259)S(0.032)PSR 171.15 2.9339e-32 0.0 11560.0 12425.0 15621.0 11687.0 11562.0 16559.0 12969.0 19342.0 14328.0 13920.0 True False 15235.839537062797 16441.13826588211 15413.855333419913 8992.742712350064 9956.8158746473 15523.563112303973 14123.21587571796 16353.138334943256 15085.348828808268 13432.665036918248 1.1342380305910045 1.2239669656539036 1.1474904861437827 0.669468246817327 0.7412390502764755 1.1556577246316435 1.0514083271563615 1.2174157763927262 1.1230346909826006 1.0 13.713457942997856 -9.27145526573673 15.416099442505196 1.0000089593975618 1.047011896264999 0.006607588308524925 0.18212464827247157 0.0 0.0 0.1964025563759855 0.04763461676938328 5.352352825466794e-10 9.27145526573673 0.04700293686743717 SQSFNTDTTTSGISSMS(ph)SSPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSFNTDTTTSGISSMSSSPSR 22 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 SQSFNTDTTTSGISS(0.033)MS(0.456)S(0.456)S(0.053)PS(0.001)R 158.91 1.9469e-23 0.0 12009.0 20028.0 20105.0 16718.0 20456.0 14890.0 17158.0 10414.0 13541.0 13737.0 True False 14041.886511438366 22016.247479559155 20584.379448637086 15781.344660487297 16447.793644624686 14109.14218765309 15532.670026837388 10140.643534545075 13739.011507944815 16227.409357967841 0.8653190538108686 1.3567321187191799 1.268494495612753 0.9725116506497988 1.013580990150386 0.8694636264121446 0.9571872924503918 0.6249083455558422 0.846654644920189 1.0 13.986145077233502 -6.415390248537096 1.236175142796026 0.8291200358701004 1.1703238693249334 0.38045608743677084 0.15671976860376097 0.4240214939493419 1.340502261725532 0.06677261093151088 0.08332826374416236 3.8424635060557663e-07 6.415390248537096 0.34120383345483296 SQSFNTDTTTSGISSMS(ph)SSPSR ddPTM_PC-9_Lapatinib_30min_R1 2 SQSFNTDTTTSGISSMSSSPSR 22 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 SQSFNTDTTTSGIS(0.028)S(0.028)MS(0.437)S(0.437)S(0.068)PS(0.003)R;SQSFNTDTTTSGISS(0.001)MS(0.491)S(0.491)S(0.017)PSR 180.56 3.8565e-32 5155700.0 18031.3 22182.0 24293.0 18634.2 25516.0 24913.0 24569.0 22041.2 22510.0 19536.8 True False 17774.170355464554 22130.638941858026 22295.72331369181 20004.62122986894 24015.19904638613 23847.52906503948 25841.06260295973 23065.314617356595 19974.686759191507 22913.709848850347 0.7757002455172636 0.9658252237565271 0.9730298350099104 0.8730415703885958 1.0480711855392133 1.0407537331296 1.1277555128968457 1.006616334478629 0.8717351703828833 1.0 14.4839234369368 -3.7995477604093884 0.8057938853315353 1.0092644220945721 3.4651502356203494e-14 0.42819249951561644 0.0737165113924114 10.78251624537918 1.6499836426622183 0.02818399896254741 14.10435126909556 0.00015865444332477952 3.7995477604093884 -1.0092644220945375 SQSFNTDTTTSGISSMSS(ph)SPSR ddPTM_PC-9_AZD4547_30min_R2 1 SQSFNTDTTTSGISSMSSSPSR 22 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 SQSFNTDTTTSGIS(0.003)S(0.025)MS(0.158)S(0.467)S(0.301)PS(0.045)R 87.79299999999999 0.00092737 0.0 5186.2 5462.8 10655.0 10662.0 9940.7 8452.6 5315.7 12735.0 10093.0 7925.3 True False 6835.303720338673 7228.543269123609 10513.70773814667 8204.04062625792 8560.605393972182 7924.057585787826 5788.7870021246 10767.098371187172 10626.49537473212 7647.837659273578 0.8937563825051064 0.9451747789597047 1.3747294603459592 1.0727268270803192 1.1193497790309141 1.0361173888385706 0.7569181329451026 1.4078617840601333 1.3894771108074837 1.0 12.900836184203722 -7.791503188739266 24.999467996350266 1.2990021140571322 1.0440157564133834 0.2498941648492199 0.18443012988021867 285.31420808238954 237248.34670571226 0.10197982576119945 0.0489994444344808 1.6162063593207934e-08 7.791503188739266 -0.2549863576437488 SQSFNTDTTTSGISSMSS(ph)SPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSFNTDTTTSGISSMSSSPSR 22 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 SQSFNTDTTTSGISS(0.002)MS(0.221)S(0.754)S(0.023)PSR 210.67 4.1999999999999987e-79 0.0 10747.0 16978.0 14619.0 11579.0 16457.0 11143.0 17369.0 9232.4 10802.0 10305.0 True False 12566.254837074535 18663.463636306933 14967.572402866243 10930.266169624503 13232.368987562986 10558.641463869604 15723.682579329668 8990.059282536393 10959.958814623735 12173.21492566489 1.0322872728206742 1.5331581468227098 1.2295496706716305 0.8978947826329865 1.0870069302452776 0.8673667168735133 1.2916622827532025 0.7385115055828495 0.9003339612050029 1.0 13.571422611265417 -5.655900000093784 5.278874164920714 0.9728840836188181 1.304464594984602 0.3646753476699265 0.17886685862626744 0.2010093394997564 8.56473005147306 0.04715918433585499 0.08287843769329002 2.208513202957908e-06 5.655900000093784 0.33158051136578404 SQSGEDES(ph)MNQPGPIK ddPTM_PC-9_AZD4547_30min_R2 2 SQSGEDESMNQPGPIK 16 0 A0A0C4DG33;O43933-2;O43933 A0A0C4DG33 PEX1 Peroxisome biogenesis factor 1 1 SQS(0.004)GEDES(0.996)MNQPGPIK;SQSGEDES(1)MNQPGPIK 178.95 5.4916999999999994e-06 15974400.0 63966.0 61703.0 79977.0 101522.0 87924.0 78486.0 67689.0 81294.0 74194.0 76382.0 True False 84305.85742454646 81647.28808207023 78916.45272395646 78117.67139926442 75717.27027871365 73578.25801269959 73713.18986903163 68731.88025027809 78115.74336994693 73707.88942887123 1.1437833599332994 1.10771436700627 1.0706649360800318 1.0598278149674691 1.027261408044813 0.9982412816704412 1.000071911435824 0.9324901415961037 1.059801657261253 1.0 16.169531428052153 -5.559641711052147 0.6967826145189885 0.9905569032932762 1.163250683475998 0.736599560298915 0.029811507390269824 0.6443124303177092 0.4620684793040547 0.01460185676874465 0.07570970260939212 2.756501854188161e-06 5.559641711052147 0.17269378018272175 SQSGEDES(ph)MNQPGPIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQSGEDESMNQPGPIK 16 0 A0A0C4DG33;O43933-2;O43933 A0A0C4DG33 PEX1 Peroxisome biogenesis factor 1 1 S(0.002)QS(0.267)GEDES(0.731)MNQPGPIK;SQSGEDES(1)MNQPGPIK 134.75 5.1674e-06 15486100.0 105624.0 120898.0 132331.0 132807.0 162523.0 132445.0 152868.0 143608.0 133510.0 111390.0 True False 123504.0570309072 132899.9544529533 135486.27290811192 125366.25435610363 130677.78483111733 125499.35104390299 138387.2363715221 139838.44216525325 135462.33117389504 131584.12523724537 0.9385938980726599 1.0099999085249494 1.029655155314754 0.9527460408318179 0.9931120839653422 0.9537575358549402 1.0517016100689256 1.06273034010087 1.029473205294767 1.0 17.00562592230206 -7.272781731248618 24.968356675888433 1.041203820441948 0.9826866841601211 0.44890729349605263 0.03024435155169031 675.9295069191688 1487943.6944052652 0.012531135958833012 0.008533322543498603 5.3360300757366515e-08 7.272781731248618 -0.058517136281826976 SQSGEDES(ph)MNQPGPIK ddPTM_PC-9_Lapatinib_30min_R1 2 SQSGEDESMNQPGPIK 16 0 A0A0C4DG33;O43933-2;O43933 A0A0C4DG33 PEX1 Peroxisome biogenesis factor 1 1 SQS(0.002)GEDES(0.998)MNQPGPIK;SQSGEDES(1)MNQPGPIK 113.67 0.00018373 11903000.0 48777.0 57897.0 63332.0 53462.0 63421.0 72140.0 63997.0 63960.0 72616.0 57276.0 True False 48081.43103539373 57762.94305368108 58125.0874285897 57393.77382400386 59690.7014704834 69054.74036655361 67310.451520274 66931.81509745964 64437.221399620226 67176.08028452724 0.7157522563350335 0.8598736754068352 0.8652646475114109 0.8543781295501317 0.8885707712873513 1.0279662057397398 1.0020002839578854 0.9963638070867933 0.9592286588722286 1.0 16.035659996511352 -4.9173363000751085 0.4236447484428995 1.0099880169026942 0.5829594578862857 0.8167500775812078 0.03962423796858002 2.155634441190697 0.3307294028056241 0.03388008533306129 0.4621876854408142 1.2096610582004467e-05 4.9173363000751085 -0.42702855901640857 SQSGT(ph)LDGESAAWSASGEDSR ddPTM_PC-9_AZD4547_30min_R2 1 SQSGTLDGESAAWSASGEDSR 21 0 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4 P49815 TSC2 Tuberin 1 SQS(0.053)GT(0.855)LDGES(0.092)AAWSASGEDSR 207.1 3.1710999999999997e-24 13842000.0 13969.0 11576.0 19582.0 27058.0 25248.0 20763.0 19594.0 24331.0 17078.0 19600.0 True False 18410.85142675001 15317.715618982003 19322.329885348503 20820.19614193274 21742.751012203335 19464.68632772314 21337.828041392368 20571.203020758156 17980.708214571983 18913.80996577569 0.9734078675879806 0.8098693836249399 1.0215990284512757 1.1007933451592584 1.1495701316417253 1.0291256157772681 1.128161278980962 1.0876287251474714 0.9506655849407315 1.0 14.207152386151698 -5.446778366518896 5.479132410316613 1.0715946670352774 0.8934334653661822 0.5004031665692726 0.06740759440408618 0.15756871490833577 8.301467803553061 0.01725803411222042 0.03634990082727308 3.5745521171283842e-06 5.446778366518896 -0.17816120166909521 SQSGT(ph)LDGESAAWSASGEDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSGTLDGESAAWSASGEDSR 21 0 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4 P49815 TSC2 Tuberin 1 SQS(0.053)GT(0.889)LDGES(0.058)AAWSASGEDSR 210.71 1.2013e-24 13666000.0 8777.4 11610.0 14708.0 16113.0 23983.0 18980.0 18571.0 15785.0 16588.0 16971.0 True False 10263.240458447748 12762.564072183042 15058.69450040061 15210.240849050828 19283.703313406022 17984.65538761959 16811.820437603277 15370.66047558998 16830.56811858716 20047.707957637926 0.511940840326217 0.6366096363310533 0.7511429502175802 0.7587022357464019 0.9618906736946541 0.8970928460062519 0.8385906495210184 0.7667041293732509 0.8395258028574247 1.0 14.291149683203729 -5.152118996347536 1.0584693689479405 0.8678817466992158 0.45107306077148174 0.7603260593922907 0.06808649165173182 0.5484784759126262 0.755591114188126 0.023925174718022708 0.22412790133198032 7.0450001006896104e-06 5.152118996347536 -0.41680868592773407 SQSGT(ph)LDGESAAWSASGEDSR ddPTM_PC-9_Lapatinib_30min_R1 2 SQSGTLDGESAAWSASGEDSR 21 0 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4 P49815 TSC2 Tuberin 1 S(0.254)QS(0.116)GT(0.569)LDGES(0.06)AAWSASGEDSR;SQS(0.124)GT(0.875)LDGESAAWSASGEDSR 201.96 2.3177e-19 28393000.0 35919.0 33244.0 34273.0 31880.0 29914.0 33516.0 26059.0 30555.0 39693.0 23418.3 True False 35406.78847326211 33167.02556050527 31455.206237605893 34224.56154856241 28154.517333186825 32082.598809612 27408.207512333745 31974.696846511553 35222.35635417987 27466.12195207669 1.2891076699885196 1.207561286532391 1.1452365314801054 1.2460645739605303 1.0250634356867439 1.1680789470603172 0.9978914227554951 1.1641503996196294 1.2823927752027162 1.0 14.745365604653161 -4.069163802046569 0.634613453857447 1.117454259837953 1.6082936080330013 0.2633296881997368 0.09048854331911572 11.09948751937429 1.7459691725636317 0.040313520563194816 4.854674813581767 8.527784124968787e-05 4.069163802046569 0.49083934819504815 SQSLPGADS(ph)LLAKPIDK ddPTM_PC-9_AZD4547_30min_R2 1 SQSLPGADSLLAKPIDK 17 1 H0Y4W2;F2Z2U4;Q9Y4A5-2;Q9Y4A5 H0Y4W2 TRRAP Transformation/transcription domain-associated protein 1 S(0.008)QS(0.105)LPGADS(0.887)LLAKPIDK 77.051 0.0037408999999999997 23515000.0 97158.0 87406.0 106560.0 111080.0 104810.0 105570.0 120290.0 188470.0 139200.0 114350.0 True False 128052.22298805759 115658.28018251031 105146.94477493278 85472.2221688923 90258.94065229042 98968.69121118018 130995.57696739271 159346.2921097482 146557.8278175678 110346.64130543113 1.160454196640374 1.0481359361213085 0.9528785247200594 0.7745792817772467 0.8179582050210348 0.8968890220885143 1.1871279036468985 1.444052036606078 1.328158483880872 1.0 16.751683192448162 -7.390533769583699 4.130986719470373 1.2934972649870262 0.9345943444147652 0.49318105526738876 0.14719844135760576 0.18671189227018045 5.348604648349651 0.06842918180992034 0.04442730768066841 4.068798946808068e-08 7.390533769583699 -0.35890292057226103 SQSLPGADS(ph)LLAKPIDK ddPTM_PC-9_Lapatinib_30min_R1 1 SQSLPGADSLLAKPIDK 17 1 H0Y4W2;F2Z2U4;Q9Y4A5-2;Q9Y4A5 H0Y4W2 TRRAP Transformation/transcription domain-associated protein 1 S(0.026)QS(0.321)LPGADS(0.653)LLAKPIDK 90.882 0.0010900999999999999 17079000.0 36543.0 41354.0 34645.0 33473.0 64308.0 61505.0 85278.0 75039.0 69438.0 77074.0 True False 36021.89011883454 41258.24735378218 31796.62183356742 35934.716082654646 60525.52987439254 58874.57452515767 89693.27757154136 78525.58588333777 61617.161225443764 90396.13820535064 0.39848925887745906 0.4564160391460181 0.35174756869962553 0.39752490312166494 0.6695588005861292 0.6512952399737894 0.9922246608343753 0.8686829707808221 0.6816348845065661 1.0 16.463973520431118 -6.631664462030546 1.4726827494604804 0.868776944905513 0.39624248613951263 0.813868722509519 0.10045454002387569 0.16563915682621902 0.7448499616779658 0.04277343546642159 0.04322029093860012 2.3352615996302664e-07 6.631664462030546 -0.4725344587660004 SQSLPHS(ph)ATVTLGGTSDPSTLSSSALSER ddPTM_PC-9_AZD4547_30min_R2 1 SQSLPHSATVTLGGTSDPSTLSSSALSER 29 0 F8WDP1;A0A0A0MRY0;Q8WUA7-3;Q8WUA7-4;Q8WUA7 F8WDP1 TBC1D22A TBC1 domain family member 22A 1 S(0.016)QS(0.192)LPHS(0.451)AT(0.291)VT(0.05)LGGTSDPSTLSSSALSER 132.33 7.2756e-12 82826000.0 83819.0 84017.0 176530.0 294850.0 212910.0 167740.0 149680.0 240600.0 180110.0 154180.0 True False 110471.69845649334 111173.85220801744 174189.09685734683 226876.8878870895 183351.12159411525 157251.19128316166 163001.23003141858 203420.7984379773 189630.24689814754 148782.20512873962 0.7425061240415369 0.7472254636353852 1.1707656618385438 1.5248926287305355 1.2323457730409595 1.0569220367925984 1.095569392121695 1.3672387652942737 1.2745492428618233 1.0 17.182842459836223 -5.285659953882362 4.833277613673617 1.2329307186202767 0.7386833012760415 0.627659732893835 0.14498732724742655 0.1123605099686012 7.269351505125822 0.03982430185277857 0.09350145911392792 5.180122691036375e-06 5.285659953882362 -0.49424741734423516 SQSLPHS(ph)ATVTLGGTSDPSTLSSSALSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSLPHSATVTLGGTSDPSTLSSSALSER 29 0 F8WDP1;A0A0A0MRY0;Q8WUA7-3;Q8WUA7-4;Q8WUA7 F8WDP1 TBC1D22A TBC1 domain family member 22A 1 S(0.07)QS(0.215)LPHS(0.293)AT(0.293)VT(0.127)LGGT(0.001)SDPSTLSSSALSER 59.302 0.00081717 66177000.0 24179.0 19594.0 29779.0 26927.0 34188.0 29053.0 25928.0 30738.0 27503.0 24999.0 True False 28272.02714298178 21539.162827765234 30489.044297486405 25418.367488511874 27489.106820611483 27529.40953511655 23471.912137535837 29931.160069603106 27905.17934443588 29531.1208080249 0.9573638375181152 0.7293716675295338 1.0324377627144172 0.860731553460192 0.9308521339000952 0.9322168878749634 0.7948195495227356 1.013546362299581 0.9449414238572624 1.0 14.849948492319788 -7.794573066635885 24.998915763047854 0.9844329743277094 0.8922687519091871 0.22142544004454778 0.08163651212295259 301.1547818999423 227213.25570893934 0.04212019153516926 0.020235872898574148 1.604822236645054e-08 7.794573066635885 -0.09216422241852229 SQSLPHSAT(ph)VTLGGTSDPSTLSSSALSER ddPTM_PC-9_AZD4547_30min_R2 1 SQSLPHSATVTLGGTSDPSTLSSSALSER 29 0 F8WDP1;A0A0A0MRY0;Q8WUA7-3;Q8WUA7-4;Q8WUA7 F8WDP1 TBC1D22A TBC1 domain family member 22A 1 S(0.028)QS(0.08)LPHS(0.185)AT(0.58)VT(0.126)LGGTSDPSTLSSSALSER 98.98 2.0281e-10 92382000.0 47259.0 41732.0 120310.0 191190.0 124410.0 116190.0 88389.0 140590.0 111220.0 128670.0 True False 62286.37895173446 55221.05288626097 118714.61079084246 147114.09935605442 107137.81897291746 108924.62093233866 96255.44976781803 118865.04593680435 117098.8621398698 124165.30246410001 0.5016407781855431 0.4447381981147839 0.9561013297186345 1.1848245559470176 0.8628643980784751 0.8772549075361219 0.7752201932230498 0.9573129012525208 0.9430884459346174 1.0 16.92190254850584 -5.262380027046956 24.94891103251789 0.9402670511233141 0.4731894508790038 0.7757292396828932 0.10136408352859823 36.134538661834426 958432.9499280789 0.028348864684990857 0.06503764227556252 5.4653750888710655e-06 5.262380027046956 -0.4670776002443103 SQSLPNS(ph)LDYTQTSDPGR ddPTM_PC-9_AZD4547_30min_R2 2 SQSLPNSLDYTQTSDPGR 18 0 H0YNE5;H0YLG5;Q96TC7 H0YNE5 RMDN3 Regulator of microtubule dynamics protein 3 1 S(0.011)QS(0.172)LPNS(0.817)LDYTQTSDPGR;SQS(0.01)LPNS(0.981)LDY(0.001)T(0.007)QTS(0.001)DPGR 208.37 2.3435e-20 153566000.0 57526.0 47856.0 80513.0 91363.0 80903.0 54651.0 71991.0 82732.0 67351.0 68634.0 True False 75818.07138486796 63324.51612491383 79445.34501374028 70300.67189427906 69671.01493743203 51233.6643306072 78398.05953495357 69947.67039223075 70911.0363602084 66231.14455056387 1.1447495268179306 0.9561138729313219 1.1995164141107073 1.0614443155305633 1.0519373537964758 0.7735584924324098 1.1837038309839403 1.056114474042186 1.0706599869502735 1.0 16.015222169430196 -6.256270628116987 4.046968792539113 1.0203571060995567 1.0900731198957594 0.08404373251162944 0.11224203763486391 0.6425976854036666 25.214252652757402 0.03522201475604503 0.04349089144631081 5.542802087846936e-07 6.256270628116987 0.06971601379620274 SQSLPNS(ph)LDYTQTSDPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SQSLPNSLDYTQTSDPGR 18 0 H0YNE5;H0YLG5;Q96TC7 H0YNE5 RMDN3 Regulator of microtubule dynamics protein 3 1 S(0.002)QS(0.04)LPNS(0.93)LDY(0.003)T(0.011)QT(0.004)S(0.011)DPGR;SQS(0.001)LPNS(0.995)LDYTQTS(0.003)DPGR;S(0.001)QS(0.008)LPNS(0.625)LDY(0.031)T(0.043)QT(0.014)S(0.277)DPGR;SQS(0.307)LPNS(0.679)LDYT(0.014)QTSDPGR 241.11 6.0663e-44 128302700.0 108325.0 115370.4 104572.0 113410.9 109362.0 95829.1 101021.9 112890.0 93572.1 84192.79999999999 True False 126662.28298372537 126823.61085558895 107065.39307151822 107056.85495609872 87933.30116168584 90803.65329851082 91452.3742967805 109926.75711684211 94940.41494147867 99456.28817016167 1.2735472569317732 1.2751693551905336 1.0765070267687649 1.076421178849276 0.8841401864026844 0.9130006253918617 0.9195232999276313 1.105277093478155 0.9545943920513431 1.0 16.60177496855834 -5.464280766046671 1.541907388566921 0.9672694767246589 1.2976417206068274 0.7727796625055501 0.06395070523834928 0.21626671943252174 0.9451674035541512 0.020774234205179525 0.07215077578807155 3.4333591368654767e-06 5.464280766046671 0.33037224388216846 SQSLPNS(ph)LDYTQTSDPGR ddPTM_PC-9_Lapatinib_30min_R1 3 SQSLPNSLDYTQTSDPGR 18 0 H0YNE5;H0YLG5;Q96TC7 H0YNE5 RMDN3 Regulator of microtubule dynamics protein 3 1 SQS(0.003)LPNS(0.931)LDY(0.002)T(0.034)QTS(0.03)DPGR;SQS(0.007)LPNS(0.975)LDYTQTS(0.017)DPGR;SQS(0.102)LPNS(0.89)LDYT(0.006)QTS(0.001)DPGR 223.06 9.0554e-35 154861000.0 275731.0 211802.0 215281.0 152995.0 180879.0 201001.0 170447.0 130670.0 201707.0 137425.0 True False 271799.0253771273 211311.585482076 197581.42718869183 164246.7626763582 170240.05284179642 192404.65578621606 179271.91165642368 136741.405234288 178988.63359112572 161178.7281426977 1.6863206982033832 1.3110389188267682 1.2258529985034092 1.0190349841385038 1.0562191103225258 1.1937347936873706 1.1122554056742981 0.8483836968438265 1.1104978656529676 1.0 17.29830182855048 -1.5228787832165696 0.6582007465242858 1.0357291221325142 62.70347238822352 0.8281191134210569 0.08923148874802776 90.99088456839463 0.5692907558165887 0.03824803106020394 8191.0329915008315 0.029999997379458045 1.5228787832165696 61.667743266091 SQSLPNSLDYT(ph)QTSDPGR ddPTM_PC-9_AZD4547_30min_R2 1 SQSLPNSLDYTQTSDPGR 18 0 H0YNE5;H0YLG5;Q96TC7 H0YNE5 RMDN3 Regulator of microtubule dynamics protein 3 1 SQSLPNS(0.242)LDY(0.001)T(0.704)QT(0.001)S(0.052)DPGR 161.48 9.3543e-06 45857000.0 15094.0 14898.0 23952.0 25500.0 22924.0 21871.0 16462.0 26851.0 19804.0 17619.0 True False 19893.578025296356 19713.48715373132 23634.38083004121 19621.368971072683 19741.39829704331 20503.402912567206 17927.086108880318 22701.79492459733 20850.79900933269 17002.164172806224 1.1700615182339402 1.1594692859901723 1.3900807326541849 1.1540512591012204 1.1611109089640659 1.2059290043417514 1.0544002473257752 1.3352297209850066 1.2263614677172738 1.0 14.053430775480349 SQSLPNSLDYTQTS(ph)DPGR ddPTM_PC-9_AZD4547_30min_R2 1 SQSLPNSLDYTQTSDPGR 18 0 H0YNE5;H0YLG5;Q96TC7 H0YNE5 RMDN3 Regulator of microtubule dynamics protein 3 1 SQSLPNS(0.227)LDYT(0.092)QT(0.051)S(0.629)DPGR 198.52 1.0116e-14 110120000.0 64760.0 48169.0 97766.0 98221.0 84339.0 67020.0 93956.0 92672.0 74804.0 73533.0 True False 85352.33290832053 63738.68725386521 96469.55896083037 75577.66594932273 72629.98564710945 62829.228805278806 102317.90198311037 78351.67179070736 78757.9867246072 70958.6320517033 1.2028463689397142 0.8982513530901025 1.3595183020233363 1.065094742726351 1.0235539151063162 0.8854346115282904 1.441937351731322 1.1041880251245146 1.1099141069577128 1.0 16.11469057702317 -7.221726738994452 24.999974159397464 1.1726930830867328 1.0750235420649974 0.06638266216638489 0.16678298593969895 1517.7179714741462 955438.0089469218 0.06271344463805235 0.04857709228599382 6.001685875838862e-08 7.221726738994452 -0.09766954102173542 SQSLPT(ph)TLLSPVR ddPTM_PC-9_AZD4547_30min_R2 2 SQSLPTTLLSPVR 13 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 S(0.005)QS(0.068)LPT(0.463)T(0.463)LLSPVR;SQS(0.026)LPT(0.487)T(0.487)LLSPVR 160.46 0.00065695 321830000.0 109246.0 87601.0 133652.0 166947.0 152068.0 153620.0 124022.0 157023.0 107418.0 111591.0 True False 143983.95554203846 115916.31011907762 131879.6871533345 128459.94845543828 130955.98308474863 144014.1171152933 135059.71773755032 132758.7033795778 113095.89618180653 107684.2330556569 1.3370941265618703 1.076446447449423 1.2246889206628058 1.19293182307426 1.216111025437342 1.3373742193145324 1.2542199902909121 1.2328518262368187 1.0502549256524174 1.0 16.716447502799774 -8.331743165852833 3.6646675853939548 1.0045166684385616 1.231209343504487 0.5904980236286879 0.07000798524134214 0.1651777317688701 4.086388195701182 0.06641094598053 0.017998821490909374 4.6586151441248325e-09 8.331743165852833 0.2266926750659255 SQSLPT(ph)TLLSPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQSLPTTLLSPVR 13 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 S(0.171)QS(0.143)LPT(0.343)T(0.343)LLSPVR;S(0.006)QS(0.082)LPT(0.456)T(0.456)LLSPVR 153.14 0.00035158 194053000.0 36706.0 37019.0 46293.0 41435.0 55558.0 48740.0 48069.0 36866.0 41585.0 31827.0 True False 42919.6008234538 40694.0016699521 47396.80068718015 39113.5312840825 44671.80872644005 46183.98859813376 43515.55633057734 35898.306562755795 42193.101953909274 37596.98315760663 1.1415703393949124 1.082374122927969 1.2606543585822476 1.0403369632110773 1.188175352771677 1.2283961296716384 1.1574214917234193 0.9548188058672161 1.1222470105390028 1.0 15.19832928192639 -7.73834559669451 24.74006864754507 1.028899707711996 1.1575663238462706 0.41365872416552696 0.07160328052877635 191.29585936939813 204933.04735374887 0.032586623328215956 0.018797936752410253 1.8266460551798258e-08 7.73834559669451 0.12866661613427466 SQSLPTT(ph)LLSPVR ddPTM_PC-9_AZD4547_30min_R2 1 SQSLPTTLLSPVR 13 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 S(0.003)QS(0.002)LPT(0.274)T(0.718)LLS(0.003)PVR 172.85 0.00049305 131120000.0 62108.0 48196.0 50982.0 94701.0 72378.0 66844.0 51038.0 67239.0 41748.0 55073.0 True False 81857.05207334734 63774.41447585147 50305.94536895294 72869.14756586494 62329.56403522081 62664.23411310151 55580.28312629295 56848.75754850837 43954.7140497688 53144.911032916585 1.5402613436053585 1.2000098078318588 0.9465806676728603 1.3711406445055798 1.1728228126417501 1.1791201244892273 1.045825123159355 1.069693343042718 0.8270728691698136 1.0 15.697643930589425 -1.5228787452803376 0.22026640312246837 0.9477277395579262 3.3314482275133375 0.47736343169032114 0.142468861777958 51.55882413706015 0.6595902976374439 0.23237782869940238 43.700986551187235 0.029999999999999995 1.5228787452803376 2.3837204879554115 SQSLPTTLLS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 2 SQSLPTTLLSPVR 13 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 SQS(0.02)LPT(0.006)T(0.006)LLS(0.967)PVR;SQSLPTTLLS(1)PVR 113.67 0.00031869 15696700.0 28228.0 31258.0 43594.0 49750.0 41357.0 31022.0 30227.0 45328.0 31276.0 39800.0 True False 37203.91682112531 41361.53721649443 43015.915076186415 38280.90612983791 35615.29442378379 29082.189435949862 32917.144442541954 38323.599133817996 32929.185508780494 38406.614114177166 0.9686851517429677 1.0769378704806603 1.1200132078372356 0.9967269183384522 0.9273219013242042 0.7572182580191221 0.8570696793183634 0.9978385238513247 0.857383194750959 1.0 15.229067162580138 -6.189761481880274 3.0293492704840648 0.8884139360520733 1.0565535340467087 0.4640898123246242 0.07568277591697922 0.22678536912581665 4.087789426472049 0.024407446983688588 0.03202983716210547 6.460089250668745e-07 6.189761481880274 0.1681395979946354 SQSLPTTLLS(ph)PVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQSLPTTLLSPVR 13 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 SQSLPT(0.002)T(0.002)LLS(0.997)PVR;SQSLPTT(0.001)LLS(0.998)PVR 127.66 0.00011435 15032900.0 46427.0 42693.0 65135.0 48717.0 74845.0 64879.0 59535.0 46183.0 57140.0 42901.0 True False 54286.17412495199 46931.27889179246 66688.06542586317 45987.54443264501 60179.65952932802 61476.63102704797 53895.41380392607 44970.7451849333 57975.56440174044 50678.61169587089 1.071185107649171 0.9260569167409978 1.315901584401466 0.9074349689889376 1.187476482001405 1.2130685701490294 1.0634745507110503 0.8873712929392925 1.143984857944798 1.0 15.629089382976158 -7.5297839684287196 24.859673939258787 1.0044914225737984 1.1031993378045535 0.09314028661267659 0.1297458606206176 383.7964669578391 1381689.9081747045 0.058806503039110544 0.0340456206462276 2.9526776150271872e-08 7.5297839684287196 0.09870791523075506 SQSLPTTLLS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 2 SQSLPTTLLSPVR 13 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 SQSLPTTLLS(1)PVR;SQSLPT(0.001)T(0.001)LLS(0.999)PVR 148.18 4.6298e-05 13698200.0 44267.0 40172.0 35598.0 33082.0 37261.0 33711.0 30379.0 27042.0 31039.0 13442.1 True False 43635.7444624264 40078.98420216035 32671.269852253798 35514.96063831688 35069.381237944595 32269.2591141792 31951.875974411392 28298.470041674555 27543.060964839853 15765.549074527627 2.7677909761435844 2.542187653135145 2.072320456319578 2.2526941795955806 2.2244313263155635 2.0468211390313447 2.0266897031855358 1.7949561989817626 1.7470410218278496 1.0 13.944487795895066 -7.66425745311619 0.10573318001242447 1.485115193858892e-12 3.792630889249296 0.9276548263239168 0.12294351093930501 2.6120330002917806 0.2517178063276741 3.8792605888837715 4.432783557915003 2.166419453931908e-08 7.66425745311619 3.792630889247811 SQSMDIDGVS(ph)CEK ddPTM_PC-9_AZD4547_30min_R2 1 SQSMDIDGVSCEK 13 0 O95155-2;O95155;O95155-4 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 SQS(0.015)MDIDGVS(0.984)CEK 117.27 0.00026127 10737000.0 23838.0 23491.0 25476.0 41517.0 41215.0 30825.0 34824.0 35413.0 29304.0 32850.0 True False 31417.988138797806 31084.00635845769 25138.17159427731 31945.89708125589 35493.00867268537 28897.507877092237 37923.26853697294 29940.734559784192 30852.949614698307 31699.93149876183 0.9911058684787682 0.9805701428620375 0.7930039721145512 1.007759183407184 1.1196556899207082 0.9115952783122243 1.1963202046179242 0.9445047085024032 0.973281270841339 1.0 14.95219210235882 -5.9751052150938335 24.99705509287337 1.0279957905554282 0.9229477303959537 0.1985261313730039 0.09267318006452636 350.8155047073061 352254.1205530782 0.02552500149227692 0.037858189971598614 1.0589971343487787e-06 5.9751052150938335 -0.10504806015947454 SQSNPILGS(ph)PFFSHFDGQDSYAAAVR ddPTM_PC-9_Lapatinib_30min_R1 3 SQSNPILGSPFFSHFDGQDSYAAAVR 26 0 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 S(0.029)QS(0.447)NPILGS(0.524)PFFSHFDGQDSYAAAVR;S(0.052)QS(0.313)NPILGS(0.606)PFFS(0.029)HFDGQDSYAAAVR;S(0.086)QS(0.253)NPILGS(0.661)PFFS(0.001)HFDGQDSYAAAVR 116.2 5.8385e-12 24065800.0 11534.5 8521.28 12221.199999999999 6342.9 9182.900000000001 10592.7 7487.599999999999 6994.7 12567.0 7336.0 True False 11370.015914831762 8501.549499705883 11216.420111196247 6809.378025294122 8642.77987627603 10139.674913789737 7875.271290891821 7319.699297407768 11151.57212362327 8604.01782539444 1.3214774940695242 0.9880906423292005 1.3036258569910675 0.7914184005054588 1.004505110480732 1.1784813931769018 0.9153016010320493 0.850730373408101 1.2960889144964132 1.0 13.070794798333047 -5.742355007005505 24.999989973062878 1.002441421858888 1.1827672007185401 0.2365946336237682 0.162516442000049 388.5695956218584 509011.26341658214 0.04273195789310189 0.07386357893086823 1.8098600469364728e-06 5.742355007005505 0.18032577885965217 SQSPAAS(ph)DCSSSSSSASLPSSGR ddPTM_PC-9_Lapatinib_30min_R1 3 SQSPAASDCSSSSSSASLPSSGR 23 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 S(0.003)QS(0.068)PAAS(0.633)DCS(0.071)S(0.071)S(0.071)S(0.024)S(0.024)S(0.024)AS(0.008)LPS(0.003)S(0.002)GR;S(0.004)QS(0.068)PAAS(0.903)DCS(0.01)S(0.01)S(0.003)S(0.001)S(0.001)S(0.001)ASLPSSGR;S(0.003)QS(0.253)PAAS(0.722)DCS(0.01)S(0.01)S(0.001)SSSASLPSSGR 151.84 4.1203e-07 566831000.0 72488.0 63241.0 86385.0 63468.0 80035.0 73690.0 71655.0 64834.0 83240.0 62207.0 True False 71454.30782732896 63094.56935001543 79282.7587557432 68135.6484430413 75327.49865486426 70538.45047978006 75364.94528939227 67846.42432815349 73864.63464394052 72959.3970643828 0.9793708651988217 0.8647901694464089 1.0866695990617954 0.9338844780051457 1.0324578009929513 0.9668178921151667 1.0329710540629427 0.9299202989339757 1.0124074158502008 1.0 16.154806186686162 -5.244328599489178 24.99908890287582 0.9957656180639091 0.9220805327316833 0.2604473269926646 0.051822970086515194 1075.3479997372924 1571093.0019669924 0.011978607900732154 0.03152457495704766 5.697330330295269e-06 5.244328599489178 -0.07368508533222573 SQSPAASDCSS(ph)SSSSASLPSSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSPAASDCSSSSSSASLPSSGR 23 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 S(0.224)QS(0.033)PAAS(0.112)DCS(0.112)S(0.37)S(0.112)S(0.034)S(0.001)SASLPSSGR 136.59 2.9715e-06 196350000.0 25493.0 25508.0 33203.0 33067.0 39129.0 35005.0 36072.0 32822.0 28154.0 26732.0 True False 29808.461390298777 28040.26566350085 33994.68544307873 31214.36319466045 31461.95333987676 33169.27617721936 32654.999021335698 31960.457277783626 28565.698987864886 31578.299989604428 0.94395396205976 0.887959949482135 1.0765204413875913 0.9884750985625007 0.9963156138941625 1.0503819454542735 1.0340961683208316 1.0121018955518506 0.9045990125265992 1.0 14.946645885687959 -5.246044140564608 24.959878464037715 1.0096014749086484 0.9159569488026621 0.40185150860191965 0.0447835352795065 767.8563334070534 1244899.5054181472 0.011298993764806491 0.029626191556008905 5.674869245783427e-06 5.246044140564608 -0.09364452610598628 SQSS(ph)DTEQQSPTSGGGK ddPTM_PC-9_AZD4547_30min_R2 3 SQSSDTEQQSPTSGGGK 17 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 S(0.005)QS(0.038)S(0.956)DT(0.001)EQQSPTSGGGK;SQS(0.105)S(0.892)DT(0.003)EQQSPTSGGGK;SQS(0.051)S(0.948)DT(0.001)EQQSPTSGGGK 233.37 9.185599999999999e-97 143605000.0 51867.1 45188.6 69654.7 90192.5 83201.3 75052.9 62892.7 77184.4 66751.7 72142.4 True False 68359.75889730026 59794.93123876385 68731.03316642747 69400.01258523433 71650.23565397802 70359.8302984141 68490.02846069609 65257.32450106469 70280.05858570353 69616.71653443741 0.9819446003817867 0.8589162806778599 0.987277719891144 0.9968871851476092 1.0292102130173675 1.0106743581278945 0.9838158400765141 0.9373800970458547 1.009528488045511 1.0 16.087146150646475 -5.419557225979545 9.58904762379001 0.9941439380414743 0.9205487804879471 0.4093631639327453 0.035607695531810944 0.3587607713325867 30.9872572707592 0.009167418536386363 0.019107514539304604 3.8057720651874016e-06 5.419557225979545 -0.07359515755352719 SQSS(ph)DTEQQSPTSGGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SQSSDTEQQSPTSGGGK 17 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 SQS(0.028)S(0.944)DT(0.028)EQQSPTSGGGK;SQS(0.003)S(0.997)DTEQQSPTSGGGK;S(0.001)QS(0.088)S(0.911)DTEQQSPTSGGGK;S(0.001)QS(0.08)S(0.918)DT(0.001)EQQSPTSGGGK 250.1 2.6963999999999997e-131 102503000.0 83537.6 103044.6 105432.4 116002.1 125241.0 113174.5 113829.6 121854.9 104960.9 90291.5 True False 97678.8657371916 113274.18688996293 107946.3082706035 109502.8784208826 100700.92510004094 107239.42998767926 103046.83623306279 118656.33799093888 106495.75459598616 106660.63420287933 0.9157911582580365 1.062005563125604 1.012053876084017 1.0266475465784033 0.9441245671622164 1.0054265173756516 0.9661187278997166 1.1124660834590812 0.9984541662617573 1.0 16.702668285843643 SQSS(ph)DTEQQSPTSGGGK ddPTM_PC-9_Lapatinib_30min_R1 4 SQSSDTEQQSPTSGGGK 17 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 SQS(0.308)S(0.674)DT(0.018)EQQSPTSGGGK;S(0.002)QS(0.025)S(0.971)DT(0.002)EQQSPTSGGGK;SQS(0.001)S(0.999)DTEQQSPTSGGGK;SQS(0.022)S(0.968)DT(0.008)EQQS(0.002)PTSGGGK 302.9 1.6653999999999992e-221 46948300.0 85256.5 101045.4 78904.9 80166.0 78278.8 69925.1 62695.7 61106.6 74062.3 68863.2 True False 84040.72667587269 100811.43558451105 72417.64370372213 86061.6750659366 73674.59488604206 66934.56647636955 65941.77657358388 63945.835716610825 65720.62386340598 80766.11236555362 1.0405444092133334 1.248189774545923 0.8966340162066279 1.0655666410736082 0.9121968698033303 0.8287456770658784 0.8164535179695952 0.7917409151400908 0.8137153310778337 1.0 16.301462477264167 -5.997039663571881 0.9576715740982886 0.8315492298508953 1.1294328541473615 0.5228834406840535 0.09587596782916344 0.4321121010513988 0.8025037141330849 0.039798414965950726 0.08779151169968383 1.0068397112410596e-06 5.997039663571881 0.2978836242964662 SQSS(ph)HSYDDSTLPLIDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSSHSYDDSTLPLIDR 17 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;H0YC95 O60716 CTNND1 Catenin delta-1 1 S(0.008)QS(0.022)S(0.954)HS(0.014)YDDS(0.001)TLPLIDR 156.08 2.7141e-05 3059000.0 2106.7 3001.7 7091.6 6051.3 2765.1 2922.8 3102.2 5772.3 2938.7 2398.9 True False 2463.322700778348 3299.6889384557976 7260.690639042768 5712.265279579304 2223.2985044364336 2769.523222704664 2808.3371580169564 5620.783241257402 2981.672928025807 2833.8015803180488 0.8692643542466651 1.1644036623359708 2.562173262048881 2.0157604961664934 0.784563929908919 0.9773172694729846 0.9910140418870702 1.9834780530493454 1.0521812637605918 1.0 11.468523030528214 -6.258168409410223 24.982374866052936 1.165873656365908 1.6829558618841396 0.19007642788520207 0.5229929364463464 552.0149686235332 4216069.975305345 0.17042063091935433 0.21079123422506468 5.518633978518199e-07 6.258168409410223 0.5170822055182316 SQSS(ph)HSYDDSTLPLIDR ddPTM_PC-9_Lapatinib_30min_R1 1 SQSSHSYDDSTLPLIDR 17 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;H0YC95 O60716 CTNND1 Catenin delta-1 1 S(0.107)QS(0.29)S(0.501)HS(0.09)Y(0.01)DDS(0.002)TLPLIDR 61.523999999999994 0.01807 10675000.0 14912.0 16763.0 30770.0 17644.0 23061.0 24057.0 18273.0 19753.0 32725.0 18436.0 True False 14699.352145474113 16724.18630341564 28240.209375634833 18941.598618658576 21704.59731967043 23028.13818960603 19219.086529524327 20670.796491871806 29039.165890472796 21622.63803557414 0.6798130792963536 0.7734572569683942 1.3060482874093944 0.8760077557370823 1.0037904387041696 1.065001326467174 0.8888409683362676 0.9559793979746442 1.3429982892326453 1.0 14.400254927074641 -5.052945352572004 10.883066794750468 1.0396223338325925 0.7030442437231584 0.4381434515534577 0.14951913485504947 0.6454161094180931 132.05145870801906 0.036870736543855594 0.09820219841324306 8.852269912479668e-06 5.052945352572004 -0.33657809010943407 SQSS(ph)TSPEGQALENR ddPTM_PC-9_AZD4547_30min_R2 1 SQSSTSPEGQALENR 15 0 O60239-2;O60239 O60239-2 SH3BP5 SH3 domain-binding protein 5 1 S(0.012)QS(0.048)S(0.376)T(0.376)S(0.189)PEGQALENR 113.53 0.00020504 5427900.0 12216.0 12634.0 20611.0 27860.0 28491.0 31104.0 13657.0 23318.0 20111.0 25931.0 True False 16100.433891415143 16717.693428664363 20337.68467301184 21437.307432709214 24535.51644045806 29159.061962987056 14872.446542885351 19714.73889433394 21174.026402579773 25023.163582782112 0.6434211980492146 0.6680887240080003 0.8127543348278214 0.8566985290165211 0.9805121706249968 1.1652827935413717 0.594347173317396 0.7878595697587661 0.8461770364299243 1.0 14.610976574995194 -5.3606127180157 2.1551670480870073 0.884216170831407 0.6404393260904437 0.3045588911357272 0.1403561586954817 0.46383006888588035 4.05312828158137 0.04247980693545437 0.13301835198777098 4.359004144934855e-06 5.3606127180157 -0.24377684474096328 SQSS(ph)TSPEGQALENR ddPTM_PC-9_Lapatinib_30min_R1 1 SQSSTSPEGQALENR 15 0 O60239-2;O60239 O60239-2 SH3BP5 SH3 domain-binding protein 5 1 S(0.244)QS(0.05)S(0.609)T(0.047)S(0.051)PEGQALENR 113.52 0.00020581 5777700.0 14766.0 12865.0 15939.0 12266.0 13291.0 16270.0 12221.0 12869.0 15171.0 15505.0 True False 14555.434132247243 12835.211882923242 14628.556946319262 13168.0825581765 12509.249511111382 15574.170027222424 12853.743582187743 13466.940720594252 13462.282222287618 18185.01859088616 0.8004079874596352 0.7058124146959027 0.8044290344388595 0.7241170798019413 0.6878876394099855 0.85642860079493 0.7068314787772442 0.7405513859272884 0.7402952136125146 1.0 14.150462780237978 -10.669255826847909 3.2902453946476515 1.0003857159151404 0.750774708636205 0.686192762429568 0.05033622806524274 11691595.56956174 17978978.18318463 47979.589521707036 0.012120067468626062 2.1416286750822957e-11 10.669255826847909 -0.24961100727893537 SQSSDT(ph)EQQSPTSGGGK ddPTM_PC-9_Lapatinib_30min_R1 1 SQSSDTEQQSPTSGGGK 17 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 S(0.001)QS(0.03)S(0.148)DT(0.733)EQQS(0.088)PTSGGGK 125.82 9.213799999999999e-05 43121000.0 56157.0 48016.0 53500.0 52061.0 59032.0 56492.0 43267.0 38292.0 49563.0 38873.0 True False 55356.19088206747 47904.821902094256 49101.43651597217 55889.73961040492 55559.85382137739 54075.96884928395 45507.1535529431 40071.18611181869 43980.6930184722 45592.14625498338 1.2141606708417867 1.0507253076917407 1.0769713766349662 1.2258633164104655 1.218627732738169 1.1860807900302184 0.9981358038824287 0.8789054563852381 0.9646550257252905 1.0 15.476497705368455 -7.382219850415959 4.148182827453055 0.9410352952586556 1.158301382028665 0.7181107786821099 0.0622431757827163 0.13420310665619306 3.8870219161252026 0.02973209572749337 0.01936149565056565 4.1474403597827024e-08 7.382219850415959 0.21726608677000936 SQSSDTEQQS(ph)PTSGGGK ddPTM_PC-9_AZD4547_30min_R2 10 SQSSDTEQQSPTSGGGK 17 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 SQSSDT(0.003)EQQS(0.931)PT(0.065)SGGGK;SQSSDT(0.021)EQQS(0.971)PT(0.005)S(0.002)GGGK;SQSS(0.003)DT(0.004)EQQS(0.99)PT(0.002)SGGGK;SQS(0.014)S(0.147)DT(0.1)EQQS(0.739)PTSGGGK;SQS(0.006)S(0.164)DT(0.364)EQQS(0.466)PTSGGGK;SQSSDT(0.001)EQQS(0.953)PT(0.041)S(0.004)GGGK;SQSSDTEQQS(0.884)PT(0.112)S(0.004)GGGK;SQSSDT(0.006)EQQS(0.937)PT(0.045)S(0.012)GGGK;S(0.006)QS(0.003)S(0.013)DT(0.053)EQQS(0.857)PT(0.054)S(0.014)GGGK;SQSS(0.001)DT(0.003)EQQS(0.814)PT(0.18)S(0.002)GGGK 248.94 3.4092999999999996e-131 484404230.0 117135.4 97118.59999999999 140623.8 173653.39999999997 151596.59999999998 137845.6 122920.7 136567.09999999998 117425.2 141137.2 True False 154382.02063232366 128510.28819226542 138759.0365300413 133620.2915482852 130550.02883779217 129226.09284095737 133860.40417105117 115463.79269475899 123632.05634370289 136196.02958682002 1.1335280558521035 0.9435685356036373 1.0188185143942647 0.9810880093469033 0.9585450415393444 0.9488242295534792 0.982851002170515 0.8477764957248993 0.9077508112297206 1.0 17.05532512067301 -1.5228787452803376 0.5598400759215302 0.9350266130470627 8.796684701011248 0.5081255667894576 0.04976671231607542 121.73954980675988 1.0803808397457448 0.024481644280155763 1155.164598958129 0.029999999999999995 1.5228787452803376 7.8616580879641855 SQSSDTEQQS(ph)PTSGGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 12 SQSSDTEQQSPTSGGGK 17 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 SQSSDT(0.29)EQQS(0.676)PT(0.026)S(0.007)GGGK;SQSSDTEQQS(0.97)PT(0.03)SGGGK;SQSSDTEQQS(0.981)PT(0.019)SGGGK;SQS(0.003)S(0.05)DT(0.05)EQQS(0.877)PT(0.019)S(0.002)GGGK;SQSSDT(0.003)EQQS(0.996)PT(0.001)SGGGK;SQSSDT(0.001)EQQS(0.993)PT(0.006)SGGGK;SQSSDTEQQS(0.927)PT(0.069)S(0.004)GGGK;SQSS(0.002)DT(0.025)EQQS(0.947)PT(0.025)SGGGK;SQSSDT(0.006)EQQS(0.992)PT(0.002)SGGGK;SQSSDT(0.02)EQQS(0.961)PT(0.019)S(0.001)GGGK;SQSSDTEQQS(0.94)PT(0.049)S(0.012)GGGK;SQSSDTEQQS(0.917)PT(0.082)S(0.001)GGGK 229.37 2.7052e-29 771945200.0 187157.8 190652.5 193293.8 210571.2 238522.7 189446.0 209538.30000000002 213075.6 190589.7 142083.30000000002 True False 218839.9190049524 209579.22022152206 197902.65726281842 198773.5783450418 191785.88918452853 179511.1182593773 189689.3152980798 207482.59127226024 193376.713802212 167841.8775592164 1.3038457516524344 1.2486706134920367 1.1791017840169016 1.1842907219320897 1.1426581492861603 1.0695252035419103 1.1301667858854558 1.2361789220277173 1.1521362642883128 1.0 17.356743196229047 -1.5228787452871637 0.4262014269960514 1.1221556361558154 4.83008504984816 0.5333370365513501 0.05720904774755593 69.98459697903215 0.8861963976560223 0.039464865148240325 222.22986560224146 0.029999999999528466 1.5228787452871637 3.7079294136923444 SQSSDTEQQS(ph)PTSGGGK ddPTM_PC-9_Lapatinib_30min_R1 9 SQSSDTEQQSPTSGGGK 17 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 SQSSDTEQQS(0.996)PT(0.004)SGGGK;SQSS(0.006)DT(0.05)EQQS(0.861)PT(0.082)SGGGK;SQSSDTEQQS(0.49)PT(0.48)S(0.03)GGGK;SQSSDTEQQS(0.928)PT(0.007)S(0.065)GGGK;SQSS(0.012)DT(0.005)EQQS(0.956)PT(0.028)SGGGK;SQSSDT(0.001)EQQS(0.998)PT(0.001)SGGGK;SQSS(0.002)DTEQQS(0.773)PT(0.209)S(0.015)GGGK;SQSS(0.002)DT(0.002)EQQS(0.929)PT(0.067)SGGGK;S(0.003)QS(0.003)S(0.015)DT(0.045)EQQS(0.561)PT(0.332)S(0.041)GGGK 302.26 1.1282999999999997e-128 377228420.0 100007.49999999999 82388.7 94975.79999999999 90435.29999999999 93923.39999999998 91991.6 80873.10000000002 84394.0 98293.09999999999 64049.01000000001 True False 98581.37471087041 82197.93402709678 87167.25634119025 97086.2136453171 88399.01027250905 88057.33371089339 85060.31340288259 88315.25333544433 87222.29600577017 75119.79603855872 1.3123221828273994 1.0942246699512452 1.1603766375569977 1.2924184937281125 1.1767738323881252 1.1722254100063567 1.132328865206469 1.1756588541602593 1.1611093294369341 1.0 16.196905525414415 -14.522878745069534 0.18311391462040036 0.22677495744384663 1.2201633448293636 0.4909595446294279 0.06033217180005663 120.3953084936091 1.1618877844366124 33.77044437368535 0.17965042032711998 3.0000000014561822e-15 14.522878745069534 0.9933883873855169 SQSSEGVSSLSS(ph)SPSNSLETQSQSLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SQSSEGVSSLSSSPSNSLETQSQSLSR 27 0 O95155-2;O95155;O95155-4 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 SQSSEGVSSLS(0.1)S(0.449)S(0.449)PS(0.001)NSLETQSQSLSR;SQSSEGVSSLS(0.002)S(0.495)S(0.495)PS(0.008)NSLETQSQSLSR;SQSSEGVSS(0.003)LS(0.046)S(0.535)S(0.335)PS(0.079)NS(0.003)LETQSQSLSR 126.91 2.0961e-12 17911200.0 33633.6 39432.0 39372.0 51300.0 63009.0 53052.0 53306.0 46886.0 52021.0 41692.1 True False 39327.10418611983 43346.54836299062 40310.77779914151 48425.82731684401 50662.838763891115 50269.85972729157 48256.469777980754 45655.29217982337 52781.708710936975 49250.547695517984 0.7985110019334621 0.8801231740806681 0.818483848105713 0.9832545947758256 1.0286756418853318 1.0206964608409086 0.9798159012630088 0.9270006998110644 1.0716979034882965 1.0 15.587852147838548 -5.79935438326272 6.1330963434917445 1.0004556191838803 0.8369295897211944 0.7901202040161701 0.03997619801950752 0.07870227389802809 7.837793064629897 0.011121000925302573 0.017055504246132596 1.587251026959708e-06 5.79935438326272 -0.1635260294626859 SQSSEGVSSLSSS(ph)PSNSLETQSQSLSR ddPTM_PC-9_AZD4547_30min_R2 2 SQSSEGVSSLSSSPSNSLETQSQSLSR 27 0 O95155-2;O95155;O95155-4 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 SQSSEGVSSLSS(0.066)S(0.931)PS(0.003)NSLETQSQSLSR;SQSSEGVSSLS(0.014)S(0.065)S(0.915)PS(0.005)NSLETQSQSLSR 172.55 1.5465e-14 25917000.0 41246.3 37348.0 60995.0 79725.0 64627.0 53869.0 48000.0 60722.0 48755.0 51390.0 True False 54361.76542366379 49420.010620053516 60186.16644657498 61345.63298897135 55654.65659322186 50500.56291422811 52271.907011678755 51338.81015274662 51332.089764694756 49590.851741898616 1.0962055200543026 0.9965549871429057 1.2136546224255416 1.2370352763499983 1.1222766828624566 1.018344334496697 1.0540635051749867 1.0352475980841276 1.0351120813947423 1.0 15.597786383954283 -6.712190770943379 6.028956660714016 1.0323381135143104 1.1367297880965275 0.41115262936888397 0.06253957149625641 0.22815533502752525 18.671558001594303 0.023227071775901813 0.022893813845413277 1.9400334989999153e-07 6.712190770943379 0.1043916745822171 SQSSEGVSSLSSS(ph)PSNSLETQSQSLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSSEGVSSLSSSPSNSLETQSQSLSR 27 0 O95155-2;O95155;O95155-4 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 SQSSEGVSSLS(0.015)S(0.253)S(0.706)PS(0.025)NS(0.001)LETQSQSLSR 126.91 4.9391999999999995e-11 8204300.0 25809.0 21017.0 30081.0 33532.0 37382.0 33722.0 33712.0 34577.0 37253.0 22808.0 True False 30177.95394901429 23103.428863485875 30798.245122827786 31653.31075221078 30057.265448932343 31953.558955811797 30518.55530625607 33669.39038735983 37797.75464924808 26942.90985197133 1.1200703307406963 0.8574956821820591 1.1430927576879515 1.174828959682497 1.115590914792492 1.1859728266683063 1.1327119258435674 1.2496567955111333 1.4028831650669884 1.0 14.71761805077675 -5.4436694796069185 7.0619682064076565 1.184262386925299 0.9892549014984432 0.3076991016721151 0.11313741356962786 0.2883656083739917 22.075623189044123 0.02903976296198898 0.060703028240564644 3.6002322707542865e-06 5.4436694796069185 -0.19500748542685586 SQSSHS(ph)YDDSTLPLIDR ddPTM_PC-9_AZD4547_30min_R2 2 SQSSHSYDDSTLPLIDR 17 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;H0YC95 O60716 CTNND1 Catenin delta-1 1 S(0.023)QS(0.071)S(0.219)HS(0.687)YDDSTLPLIDR;SQS(0.009)S(0.068)HS(0.862)YDDS(0.009)T(0.052)LPLIDR 107.57 0.0011639 9333300.0 12019.69 11357.0 53087.3 114634.0 93699.0 64712.9 26438.7 91840.5 44372.8 56836.0 True False 15841.701394916798 15027.928151760423 52383.327715374406 88206.90237764502 80690.51121246985 60666.392132992056 28791.693081451478 77648.66100973825 46718.255619133415 54846.18893953199 0.28883869054935246 0.2740013197330582 0.9550951256271809 1.608259463112255 1.4712145505940488 1.106118643902074 0.5249533949057859 1.4157530816835062 0.8518049571437017 1.0 15.743103756074762 -5.325766583322295 4.044765003495944 1.1512205692168813 0.2712534365690931 0.5588826387327059 0.2994801708184198 0.15750366258385476 5.112292989886179 0.08394943507914653 0.19619790546188465 4.723168252912741e-06 5.325766583322295 -0.8799671326477883 SQSSHS(ph)YDDSTLPLIDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSSHSYDDSTLPLIDR 17 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;H0YC95 O60716 CTNND1 Catenin delta-1 1 S(0.005)QS(0.013)S(0.105)HS(0.863)Y(0.011)DDS(0.002)T(0.001)LPLIDR 79.32600000000001 0.0036619 12959000.0 11820.0 16229.0 30054.0 23195.0 31948.0 30784.0 22374.0 19076.0 24983.0 18987.0 True False 13820.892544358521 17840.1078662755 30770.60134042969 21895.45934920461 25688.018740636955 29169.632847865192 20254.572746267597 18575.275212692708 25348.329111807514 22429.192798990694 0.6162010674312121 0.7953967860617034 1.371899631707404 0.9762036264715643 1.145293946636943 1.3005208483997612 0.9030451041099903 0.8281740399292742 1.1301489687559412 1.0 14.45309007996257 -5.035919022493109 8.585535268526781 1.0765013170535482 0.6595360767089292 0.4854919917449063 0.15956785956948907 0.23904701508307252 55.44055212856011 0.041756706400047895 0.11553946182142887 9.206212125728273e-06 5.035919022493109 -0.416965240344619 SQSSHS(ph)YDDSTLPLIDR ddPTM_PC-9_Lapatinib_30min_R1 2 SQSSHSYDDSTLPLIDR 17 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;H0YC95 O60716 CTNND1 Catenin delta-1 1 S(0.007)QS(0.019)S(0.054)HS(0.881)Y(0.017)DDS(0.015)T(0.006)LPLIDR;SQS(0.002)S(0.157)HS(0.84)YDDS(0.001)TLPLIDR 161.75 3.0541e-05 17131100.0 24973.3 17366.8 47376.2 15764.9 33432.8 41197.9 24996.1 30277.8 52744.8 18921.7 True False 24617.176162457687 17326.588241613015 43481.11171342057 16924.303336164725 31466.348435413798 39435.961853995526 26290.27575114338 31684.617122543215 46804.12519663278 22192.290633419583 1.1092670229086872 0.7807480772408748 1.9592890356231163 0.7626208405309118 1.417895473486109 1.7770117787935118 1.1846580501948096 1.4277308118355772 2.1090263267438467 1.0 14.437770966188399 -6.506837215049881 24.624093305284593 1.5168098537744976 1.1722705045230115 0.13329396997205667 0.41812055428995176 1227.7299750883844 1884594.8138634271 0.12766720937080614 0.14069368587755443 3.1128829085317105e-07 6.506837215049881 -0.3445393492514861 SQSSHSYDDS(ph)TLPLIDR ddPTM_PC-9_AZD4547_30min_R2 2 SQSSHSYDDSTLPLIDR 17 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;H0YC95 O60716 CTNND1 Catenin delta-1 1 SQSSHSYDDS(0.667)T(0.333)LPLIDR;SQSSHSYDDS(0.657)T(0.343)LPLIDR 187.57 1.3057e-08 45760000.0 10280.0 11751.9 43673.0 93831.0 57018.0 52100.0 31176.0 58667.0 36477.0 46981.0 True False 13548.82616271674 15550.471854070012 43093.86748456872 72199.71262449882 49102.03490232137 48842.178763876866 33950.603604085336 49601.3631835444 38405.09975072858 45336.20948990345 0.29885220478642166 0.34300335270713717 0.9505397114014548 1.5925396815668496 1.0830644082244367 1.0773326511726617 0.7488628622921435 1.0940783038906423 0.8471175729696049 1.0 15.468376153541204 -5.287851795751326 4.446768261402326 1.0688720127334992 0.3079915376701037 0.663160710553697 0.20860787123314356 0.11441501993572017 5.662461223659165 0.058288700933523466 0.13952246215860448 5.1540449785115685e-06 5.287851795751326 -0.7608804750633955 SQSSHSYDDS(ph)TLPLIDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SQSSHSYDDSTLPLIDR 17 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;H0YC95 O60716 CTNND1 Catenin delta-1 1 SQSSHSYDDS(0.616)T(0.384)LPLIDR;SQSSHSYDDS(0.654)T(0.346)LPLIDR;SQSSHS(0.008)YDDS(0.496)T(0.496)LPLIDR;SQSSHSYDDS(0.613)T(0.387)LPLIDR 157.47 1.3158e-05 35953800.0 30177.1 37207.399999999994 113640.0 115606.0 146326.0 138428.0 82352.0 81562.3 106176.0 74209.4 True False 35285.48700510674 40901.10477685986 116349.60858209974 109128.970619709 117654.47070997997 131168.59199143326 74551.02238315147 79421.37604740028 107728.62313474277 87662.97677871266 0.4025129912503173 0.4665721639832785 1.3272377103483566 1.244869551888283 1.3421226957302024 1.4962826590128426 0.850427684783513 0.9059853881973843 1.2288953340779396 1.0 16.41968004895468 -5.252584247835559 24.139171825403956 1.1795411101237034 0.43454234674871733 0.7014757869015786 0.1930572758465223 228.73699771330132 623533.1473172146 0.05368583960979967 0.1372529453139653 5.590050768810476e-06 5.252584247835559 -0.7449987633749862 SQSSHSYDDS(ph)TLPLIDR ddPTM_PC-9_Lapatinib_30min_R1 2 SQSSHSYDDSTLPLIDR 17 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;H0YC95 O60716 CTNND1 Catenin delta-1 1 SQSSHS(0.001)YDDS(0.824)T(0.174)LPLIDR;SQSSHSYDDS(0.67)T(0.33)LPLIDR 217.91 1.719e-22 18175400.0 41492.5 27784.8 84064.0 35357.7 48796.3 57062.0 26901.5 33976.5 84901.0 21269.8 True False 40900.8093412074 27720.46600269301 77152.58241642387 37958.023207829545 45926.19757121697 54621.59127801887 28294.32803994957 35555.1722273114 75338.55533283511 24946.256589772987 1.6395569890023167 1.1112074432064225 3.0927518980163735 1.521591949927705 1.841005579572406 2.1895706508691823 1.1342113770909086 1.4252708457223062 3.020034491416281 1.0 14.606535721983548 SQSSHSYDDST(ph)LPLIDR ddPTM_PC-9_AZD4547_30min_R2 1 SQSSHSYDDSTLPLIDR 17 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;H0YC95 O60716 CTNND1 Catenin delta-1 1 SQSSHS(0.034)YDDS(0.303)T(0.662)LPLIDR 182.49 1.2445000000000001e-06 5561600.0 2161.9 2014.4 13237.0 39035.0 21675.0 17227.0 10885.0 15508.0 13007.0 18512.0 True False 2849.3392296865113 2665.5154062610013 13061.468731097844 30036.083834738118 18665.800387733972 16149.79296670455 11853.7439129609 13111.594938387972 13694.52346568322 17863.900514614263 0.1595026364681945 0.1492123964797258 0.7311655548245132 1.6813844104296216 1.0448894054500406 0.9040462889665435 0.6635585494480044 0.7339715605593258 0.7666032093315723 1.0 14.124759501369255 -5.346285528600616 4.178960142094947 0.9618469393520336 0.1503931481596562 0.5864772680773338 0.2688165277971691 0.1614094598733648 5.109167612905476 0.07918261663360812 0.1797993263808577 4.505204107515706e-06 5.346285528600616 -0.8114537911923774 SQSSHSYDDST(ph)LPLIDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSSHSYDDSTLPLIDR 17 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;O60716-25;O60716-27;O60716-29;O60716-26;O60716-28;O60716-31;O60716-32;O60716-30;H0YC95 O60716 CTNND1 Catenin delta-1 1 SQSSHSYDDS(0.235)T(0.765)LPLIDR 144.25 0.00027226 2863400.0 4421.9 3722.9 15770.0 10529.0 15126.0 17285.0 8972.0 9341.8 12974.0 8464.7 True False 5170.44033349399 4092.4849082110454 16146.016608058042 9939.094265478563 12162.168882899534 16378.544171496555 8122.107208345083 9096.587648455272 13163.720205603437 9999.283103471667 0.5170811027141392 0.4092778318067791 1.6147174193370204 0.9939806846780639 1.2163040847075257 1.6379718427824153 0.8122689521136925 0.9097239826420169 1.3164663975793527 1.0 13.287608949535349 -5.240861737548091 24.829563099417495 1.1812339175989608 0.4631792550039975 0.545447788761739 0.2645011211689524 562.6336407640682 678886.9640915678 0.06742308016807101 0.17793280461013358 5.742992676307139e-06 5.240861737548091 -0.7180546625949633 SQSSS(ph)QFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSSSQFR 8 0 Q16537-2;Q16537 Q16537-2 PPP2R5E Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform 1 S(0.004)QS(0.354)S(0.189)S(0.453)QFR 99.973 0.013072 0.0 18732.0 12319.0 20217.0 23938.0 21760.0 20769.0 20589.0 15948.0 21449.0 13810.0 True False 21902.957626135674 13541.948906565278 20699.04995339946 22596.831468043125 17496.284205467015 19679.837078265085 18638.660868548493 15529.381898302749 21762.65104747866 16313.643680100155 1.3426159143621312 0.8300995885477216 1.2688183191501692 1.3851492597945718 1.0724939534390763 1.206342216623936 1.1425197971734826 0.9519260198900831 1.3340153477806653 1.0 13.993791425984211 -7.528930628823619 24.965078618526665 1.0952270113875004 1.1759158816611759 0.049542288222020114 0.17263613858574098 615.1588048005253 2537582.399601642 0.07927795081103077 0.04592443660361885 2.9584849966035096e-08 7.528930628823619 0.08068887027367544 SQSST(ph)SPEGQALENR ddPTM_PC-9_AZD4547_30min_R2 1 SQSSTSPEGQALENR 15 0 O60239-2;O60239 O60239-2 SH3BP5 SH3 domain-binding protein 5 1 SQSS(0.005)T(0.497)S(0.497)PEGQALENR 211.26 4.1821000000000004e-13 6072300.0 12410.0 11620.0 14807.0 19573.0 17118.0 11386.0 10071.0 18727.0 11605.0 14711.0 True False 16356.12185596446 15375.9377585151 14610.649505278066 15060.747249835516 14741.461178188243 10674.031620067222 10967.299489887855 15833.172453649173 12218.416607922945 14195.972367679911 1.1521663632709358 1.0831197300384738 1.0292109005891175 1.060916917824132 1.0384256038529809 0.7519056351764166 0.7725641615686148 1.1153284920233213 0.8606959982354373 1.0 13.793194050872021 -6.547589775102567 23.899890917556366 0.8988724552498072 1.0742447019096206 0.42053823482847963 0.10219916526939082 145.27838846889267 140508.10297076477 0.03494474131202136 0.0349466052606539 2.834067729153841e-07 6.547589775102567 0.17537224665981344 SQSST(ph)SPEGQALENR ddPTM_PC-9_Lapatinib_30min_R1 1 SQSSTSPEGQALENR 15 0 O60239-2;O60239 O60239-2 SH3BP5 SH3 domain-binding protein 5 1 SQSS(0.119)T(0.44)S(0.44)PEGQALENR 157.07 0.00054425 4965400.0 20190.0 19629.0 20972.0 21479.0 30725.0 26541.0 19638.0 19201.0 26258.0 18152.0 True False 19902.086897607467 19583.55025650216 19247.763114261106 23058.637311843555 28917.815907674176 25405.90330009284 20654.75955052802 20093.14855669673 23300.54753100181 21289.549013980348 0.9348289568998495 0.9198668437570989 0.9040944503625489 1.083096560509642 1.3583104033197004 1.1933509386887142 0.9701830478872296 0.9438033912086176 1.0944594230578057 1.0 14.37785776841033 -5.7866222457346534 7.1243208822348905 1.100327868639186 0.9193919736982951 0.3269731155948441 0.11288893836050676 0.21587960511182808 40.85688541827869 0.03596564761403306 0.05519770308916365 1.6344730129374017e-06 5.7866222457346534 -0.1809358949408909 SQSSTS(ph)PEGQALENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SQSSTSPEGQALENR 15 0 O60239-2;O60239 O60239-2 SH3BP5 SH3 domain-binding protein 5 1 SQS(0.006)S(0.054)T(0.199)S(0.741)PEGQALENR;SQS(0.001)S(0.019)T(0.221)S(0.76)PEGQALENR 168.47 0.00020211 10224500.0 26312.0 30599.0 29108.0 27875.0 33823.0 36869.0 25431.0 31477.0 25779.0 23209.0 True False 30766.10191431146 33636.66649825399 29802.045112704724 26313.25412196933 27195.625950437057 34935.524735834915 23021.991575504228 30650.762102638324 26155.96910592345 27416.607977657073 1.1221702531321172 1.2268719210511343 1.0870070118444863 0.9597560042224439 0.991939848014747 1.274246791007309 0.8397096969204141 1.1179633209045006 0.954019152450917 1.0 14.742762469392876 -5.495635865626423 6.133020505410009 1.0261058793154127 1.171666587383293 0.23760512912903742 0.1103333309987572 0.25527314516971755 32.09824184853274 0.028222723724357295 0.05654501008532039 3.1942149233671975e-06 5.495635865626423 0.14556070806788024 SQST(ph)TFNPDDMSEPEFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SQSTTFNPDDMSEPEFK 17 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.002)QS(0.02)T(0.741)T(0.235)FNPDDMS(0.003)EPEFK;S(0.035)QS(0.107)T(0.65)T(0.208)FNPDDMSEPEFK;S(0.002)QS(0.484)T(0.51)T(0.005)FNPDDMSEPEFK;S(0.016)QS(0.214)T(0.476)T(0.293)FNPDDMSEPEFK 226.08 1.1074e-32 9033800.0 90953.5 101899.0 106220.9 109368.9 139310.3 86492.5 116641.7 110639.4 98764.4 88437.9 True False 106350.13113648989 112014.85929296998 108753.60910100653 103241.3151117577 112013.44676235598 81956.68103865588 105592.55376322148 107735.23298213436 100208.64250611211 104470.99119596902 1.0179871935645364 1.072210170599894 1.0409933691258282 0.9882294972974396 1.0721966498072049 0.7844922317710158 1.0107356363179192 1.0312454371189241 0.959200648514366 1.0 16.672742874469165 SQSTT(ph)FNPDDMSEPEFK ddPTM_PC-9_AZD4547_30min_R2 2 SQSTTFNPDDMSEPEFK 17 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 SQS(0.005)T(0.113)T(0.882)FNPDDMSEPEFK;SQS(0.007)T(0.231)T(0.763)FNPDDMSEPEFK 297.55 9.285299999999997e-112 12748600.0 42064.0 48058.0 62639.0 69794.0 72716.0 68643.0 68494.0 91140.0 72826.0 73183.0 True False 55439.47701444717 63591.80867458854 61808.36593240446 53704.07160655087 62620.63856952536 64350.74235871018 74589.83330954018 77056.40718884977 76675.4336827744 70620.88544517149 0.7850294805137946 0.9004674505810301 0.8752136927027221 0.7604559369089975 0.8867155682739586 0.9112140403375527 1.0562007660956063 1.091127740796661 1.0857331113796858 1.0 16.107807289281197 -7.109600303817472 2.0785416854645304 1.0708923037098594 0.8408188788964022 0.828079222980002 0.04665893211100989 0.1268635499873479 1.0799817964589837 0.02151810961583706 0.015503942952278226 7.76961852456178e-08 7.109600303817472 -0.23007342481345727 SQSTT(ph)FNPDDMSEPEFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSTTFNPDDMSEPEFK 17 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 SQS(0.004)T(0.045)T(0.95)FNPDDMS(0.002)EPEFK 125.86 0.00014362 21479000.0 40753.0 53812.0 51959.0 47447.0 59458.0 46035.0 50097.0 50446.0 45295.0 38674.0 True False 47651.67799156029 59154.09972888142 53197.8996156048 44788.69841524945 47807.63172282431 43620.843560014095 45351.44948912885 49121.845951955176 45957.35368527886 45685.29005678447 1.043042036776645 1.2948172082382734 1.1644426367761382 0.9803746098488024 1.0464556898599502 0.9548115707658992 0.9926926026464826 1.075222372253722 1.0059551691180297 1.0 15.479442094541092 -5.722421851818941 7.072072898329286 1.009828566173905 1.1816955891605472 0.5562473147283509 0.06493764219128362 0.1337720338629186 18.29361130345127 0.016983477588164885 0.02914422853751666 1.8948644509656856e-06 5.722421851818941 0.17186702298664214 SQSTT(ph)FNPDDMSEPEFK ddPTM_PC-9_Lapatinib_30min_R1 4 SQSTTFNPDDMSEPEFK 17 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.002)QS(0.184)T(0.115)T(0.699)FNPDDMSEPEFK;SQS(0.009)T(0.084)T(0.897)FNPDDMS(0.01)EPEFK;SQS(0.013)T(0.272)T(0.714)FNPDDMS(0.001)EPEFK;SQS(0.034)T(0.088)T(0.877)FNPDDMS(0.001)EPEFK 239.93 2.4475999999999997e-37 41774600.0 135249.0 129540.0 152591.0 145413.0 164583.0 133416.0 150944.0 131347.9 153091.0 126272.0 True False 133320.32445837132 129240.05808891391 140045.55699829338 156107.15710354777 154902.55152262768 127710.10868788602 158759.14174533577 137450.80294308363 135848.27946030154 148097.94695313636 0.9002172359658625 0.8726661020480603 0.9456279433948463 1.054080494126943 1.04594665023712 0.8623354429639609 1.071987458378292 0.9281074165503329 0.9172867163600109 1.0 17.176192115461554 -5.455571709793597 4.991108562654851 0.982444192623498 0.88907934802534 0.2688464859393884 0.06293174445171187 0.28547459632639316 13.661768574546668 0.016823542544300754 0.03547100738484036 3.502904443029932e-06 5.455571709793597 -0.09336484459815797 SQSTT(ph)FNPDDMSEPEFKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSTTFNPDDMSEPEFKR 18 1 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.013)QS(0.36)T(0.122)T(0.468)FNPDDMS(0.037)EPEFKR 49.076 0.036188 18905000.0 26851.0 18644.0 27620.0 38972.0 33676.0 33006.0 27762.0 36033.0 29415.0 26490.0 True False 31396.343968576195 20494.853106096518 28278.56554943331 36788.52518892877 27077.429545188726 31275.107256257765 25132.182380525675 35087.17193011934 29845.13872728727 31292.427305275392 1.0033208246291359 0.6549460962602099 0.9036871851953142 1.1756366749704592 0.8653029463337257 0.9994465098904389 0.8031394348334493 1.1212671867165833 0.9537495585155795 1.0 14.933525950095783 -5.521818205479754 24.999967660539504 0.9855425731366793 0.81667923797604 0.20034067243707077 0.12833208267039453 51.027953111027905 1202875.296139851 0.032950848259682884 0.05802719416182215 3.0073349016140674e-06 5.521818205479754 -0.16886333516063923 SQSTTFNPDDMS(ph)EPEFK ddPTM_PC-9_AZD4547_30min_R2 1 SQSTTFNPDDMSEPEFK 17 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.001)QS(0.031)T(0.014)T(0.075)FNPDDMS(0.878)EPEFK 84.821 0.0029411999999999997 21325000.0 26714.0 33975.0 39919.0 58145.0 45968.0 55199.0 46710.0 66645.0 53211.0 49072.0 True False 35208.49631428163 44956.754332663564 39389.64797738875 44740.56858129494 39586.1366654374 51747.397803977736 50867.09951073989 56346.546599746274 56023.62482759048 47354.004216354326 0.7435167711144037 0.949375983649914 0.8318124017015021 0.9448106727549599 0.8359617591064413 1.0927776575672579 1.074187924601575 1.1899003586329508 1.1830810457258436 1.0 15.531198803528785 -6.807663676066466 5.721091503267404 1.1204300769810305 0.8688671123774148 0.7291618508935855 0.07503651787580591 0.09853283187426033 7.431199168437055 0.025704154244616875 0.023010245789242847 1.5571710606045852e-07 6.807663676066466 -0.2515629646036157 SQSTTFNPDDMS(ph)EPEFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSTTFNPDDMSEPEFK 17 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 SQSTT(0.001)FNPDDMS(0.999)EPEFK 190.66 8.9009e-09 6659000.0 30853.0 34504.0 37557.0 39404.0 50626.0 33500.0 41122.0 43338.0 33284.0 28092.0 True False 36075.80352547322 37929.32909100806 38452.50131571566 37196.32162949164 40706.19872178183 31743.20102662044 37226.62646250188 42200.4234204066 33770.7155328584 33184.85722385035 1.0871164303080114 1.1429709893025486 1.1587363795580652 1.120882376518354 1.2266498073864187 0.9565568057893052 1.1217955892167186 1.2716771127186486 1.017654386910756 1.0 15.018237446671966 SQSTTFNPDDMS(ph)EPEFK ddPTM_PC-9_Lapatinib_30min_R1 1 SQSTTFNPDDMSEPEFK 17 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2 PPFIBP1 Liprin-beta-1 1 SQST(0.001)T(0.007)FNPDDMS(0.993)EPEFK 134.75 2.9584e-05 15362000.0 144800.0 161820.0 167450.0 163080.0 193010.0 160040.0 169650.0 164770.0 180360.0 167250.0 True False 142735.12544693242 161445.3157321911 153682.90737569254 175073.44721893227 181657.53127226004 153195.4622714614 178433.64689617496 172425.81572245804 160045.95752500126 196158.93965338336 0.7276503721887371 0.8230331792039053 0.7834611445558036 0.892508123913651 0.9260731710379981 0.7809761948252817 0.9096381088288439 0.8790107452004878 0.8158993814291898 1.0 17.58166356004154 -1.5333431221169675 0.034974702715782326 1.4081686146170844 5.001855085869663e-22 0.4934545492423096 0.055311815481384335 931.7672581326293 2.5043647794327377 29.87034478512664 83.45570551449363 0.029285785551636804 1.5333431221169675 -1.4081686146170844 SQSYIPTS(ph)GCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQSYIPTSGCR 11 0 A0A087WZ32;A0A087X038;A8K727;Q9HB19;E5RHB5 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 S(0.1)QS(0.099)Y(0.002)IPT(0.112)S(0.688)GCR 77.74 0.019166 90747000.0 37061.0 40558.0 38566.0 33700.0 44215.0 35268.0 37020.0 39824.0 35791.0 27021.0 True False 43334.69531188417 44584.330201515884 39485.559702369465 31811.898256874152 35551.38815003325 33418.483994234324 33513.197598410086 38778.66219701585 36314.37566508036 31919.693401881683 1.3576162767694244 1.396765615514578 1.2370281633106717 0.9966229266788266 1.1137759909666762 1.046955043505032 1.0499222901819747 1.2148820387707682 1.1376793382025283 1.0 14.962159173662679 -5.516483361326186 4.019214500086404 1.0880009398753507 1.3706663896442115 0.781253085948026 0.06338052773371305 0.09672215003980465 3.578561988501902 0.018012107440549596 0.03630140955144228 3.0445046287347313e-06 5.516483361326186 0.28266544976886077 SQSYIPTS(ph)GCR ddPTM_PC-9_Lapatinib_30min_R1 1 SQSYIPTSGCR 11 0 A0A087WZ32;A0A087X038;A8K727;Q9HB19;E5RHB5 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 S(0.001)QS(0.094)YIPT(0.425)S(0.48)GCR 98.902 0.0047841 126810000.0 43332.0 41148.0 42147.0 34896.0 47378.0 44180.0 44205.0 36726.0 37257.0 36179.0 True False 42714.07773388442 41052.72433412556 38681.83635212484 37462.36824964347 44591.31918873185 42290.524388610145 46493.718603273825 38432.42403485466 33060.72432639706 42432.491944512745 1.0066360889136536 0.9674832293094769 0.9116088775249758 0.882869860639613 1.0508767490498112 0.9966542724832601 1.0957103029459543 0.9057310158713089 0.7791369964702811 1.0 15.372881786210693 -7.9843232697221165 24.81669278469525 0.8738569601807387 0.983801887536121 0.2313838250764818 0.07632722739141222 269.35549794374117 426396.8551649709 0.04221115334572284 0.020267444555570415 1.0367564126300107e-08 7.9843232697221165 0.1099449273553823 SQT(ph)FSPGAR ddPTM_PC-9_AZD4547_30min_R2 2 SQTFSPGAR 9 0 Q9ULE0 Q9ULE0 WWC3 Protein WWC3 1 S(0.083)QT(0.909)FS(0.008)PGAR;S(0.002)QT(0.921)FS(0.078)PGAR 91.12299999999999 0.019669 21236000.0 63513.0 39571.0 84476.0 99921.0 72001.0 54589.0 67386.0 70606.0 59361.0 74378.0 True False 83708.81284753184 52361.55189691919 83355.79304436214 76885.75721406096 62004.90397772708 51175.54120040832 73383.22345602057 59695.46506447123 62498.70127211661 71774.04885890118 1.1662824402186494 0.7295332049590161 1.1613639521469554 1.0712194509913848 0.8638902913171442 0.7130089776739925 1.022420005875422 0.8317137741779771 0.87077017760251 1.0 16.1311746866867 -6.272200251478211 23.734103874217553 0.8736276074335686 1.0197210214557013 0.21023213694849974 0.1393453580465105 587.1320459984959 1294971.6243958483 0.04206854140982597 0.04821976884598821 5.343179306904709e-07 6.272200251478211 0.14609341402213272 SQT(ph)FSPGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SQTFSPGAR 9 0 Q9ULE0 Q9ULE0 WWC3 Protein WWC3 1 S(0.001)QT(0.999)FSPGAR;S(0.002)QT(0.991)FS(0.008)PGAR;SQT(0.999)FS(0.001)PGAR;S(0.001)QT(0.979)FS(0.02)PGAR 129.0 0.003208 27403900.0 111599.0 102839.0 114416.0 141410.0 136237.0 130920.0 108521.0 149929.0 117696.0 82659.0 True False 130490.5065192781 113048.17628072639 117144.11136509628 133487.25615740538 109542.33783548739 124054.32472851196 98241.10525599842 145993.5226129067 119417.08134104361 97644.42237171606 1.336384642868002 1.1577535463354045 1.1997010020618295 1.3670750762316113 1.121849412130044 1.2704701581034274 1.006110772840776 1.49515475709543 1.2229790339323496 1.0 16.575250016631458 -6.287871763538844 24.947120393917928 1.2060714257093248 1.2528713136358327 0.05429432374731624 0.1447192930995511 3834.2274255836082 3618765.7705208375 0.044177556342802925 0.05011331688957292 5.153808013702145e-07 6.287871763538844 0.04679988792650791 SQT(ph)FSPGAR ddPTM_PC-9_Lapatinib_30min_R1 2 SQTFSPGAR 9 0 Q9ULE0 Q9ULE0 WWC3 Protein WWC3 1 SQT(0.992)FS(0.008)PGAR;S(0.011)QT(0.981)FS(0.008)PGAR 107.34 0.0061340000000000006 17392400.0 87486.0 63267.0 77872.0 68339.0 51465.0 64221.0 39972.0 43606.0 66751.0 47310.0 True False 86238.43359703246 63120.50914861293 71469.66475461285 73364.87803222096 48437.929884083016 61474.417536462905 42041.55457550188 45632.093951529496 59232.79946080823 55487.47046338754 1.5541965217883815 1.1375632844943242 1.288032490177596 1.3221881880636372 0.8729525689235367 1.1078972788465056 0.7576765389448107 0.8223855506557838 1.0674986436783416 1.0 15.759874415137022 -6.257430211619712 24.52330124559718 0.9286595491402211 1.3093955421525854 0.6534721598949496 0.13791244761212632 167.6985245058433 1025778.3055069649 0.04067314809882281 0.050552730069090446 5.528022326348093e-07 6.257430211619712 0.38073599301236427 SQT(ph)LPIIR ddPTM_PC-9_AZD4547_30min_R2 4 SQTLPIIR 8 0 Q96BY6;A0A2R8YD85;Q96BY6-3;H7C0I3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 S(0.011)QT(0.989)LPIIR;S(0.024)QT(0.976)LPIIR;S(0.032)QT(0.968)LPIIR;S(0.23)QT(0.77)LPIIR 119.34 0.0084695 128360000.0 160404.0 159698.0 248402.0 349117.0 265436.0 243405.0 237190.0 270271.0 212440.0 229253.0 True False 211409.1353895349 211317.2554353996 245108.02717701657 268633.46945388196 228584.79315887243 228184.84687181338 258299.45050208538 228506.82715972717 223669.1446951445 221226.92224918277 0.9556211931177643 0.9552058731684507 1.1079484571092795 1.2142892317206402 1.033259382876565 1.0314515274718392 1.1675769290463904 1.0329069574196967 1.0110394450238334 1.0 17.7551674397198 -5.2537778870931096 24.230078843980184 1.0812464224590974 0.9554135019214042 0.33551469801530276 0.06671988061029145 419.0654886920865 1325314.2632050135 0.017526494891074634 0.044473093087604956 5.574707854773639e-06 5.2537778870931096 -0.12583292053769324 SQT(ph)LPIIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SQTLPIIR 8 0 Q96BY6;A0A2R8YD85;Q96BY6-3;H7C0I3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 S(0.21)QT(0.79)LPIIR;S(0.208)QT(0.792)LPIIR;S(0.008)QT(0.992)LPIIR;S(0.193)QT(0.807)LPIIR 101.3 0.01132 84458100.0 159278.0 142014.0 145241.0 150267.0 169527.0 140097.0 147206.0 124815.0 131171.0 103285.3 True False 186240.61951610263 156112.21138217076 148704.09626955987 141848.02716218738 136309.4013097519 132750.06669332684 133261.58200085213 121538.73850242386 133089.12772384856 122010.1072840152 1.5264359950325395 1.2795022876159978 1.218785062809644 1.1625924304122892 1.1171976186567134 1.0880251615901881 1.0922175626863906 0.9961366415284425 1.090804120137716 1.0 16.8966411396392 -1.5228787452803478 0.4204655621869936 1.0369667989545748 9.873777695438477 0.9482236198898142 0.03381039247381644 15.133162477968826 0.1937403150027633 0.021933847678048724 112.51686403122203 0.02999999999999929 1.5228787452803478 8.836810896483902 SQT(ph)LPIIR ddPTM_PC-9_Lapatinib_30min_R1 1 SQTLPIIR 8 0 Q96BY6;A0A2R8YD85;Q96BY6-3;H7C0I3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 S(0.035)QT(0.965)LPIIR 110.54 0.009194299999999999 41568000.0 52387.0 46365.0 43848.0 38800.0 35076.0 31110.0 27078.0 29007.0 39879.0 18786.0 True False 51639.95177340079 46257.64469115713 40242.98669817474 41653.4814330057 33012.898642069296 29779.49782095204 28479.966346328438 30354.77111525971 35387.40707551302 22033.13506922847 2.343740534932828 2.099458136384807 1.8264757408208419 1.8904927193579026 1.4983296084893154 1.3515778724808964 1.2925970932799131 1.37768733409406 1.606099493527599 1.0 14.42738716859782 -1.5228787452814685 0.23848241935202738 1.1316099792003098 8.6257799214762 0.8696723225918208 0.14010168190511396 17.440332078972986 0.2323282064704727 0.20249812007901818 51.62063890996249 0.029999999999921877 1.5228787452814685 7.4941699422758905 up SQT(ph)PPGVATPPIPK ddPTM_PC-9_AZD4547_30min_R2 2 SQTPPGVATPPIPK 14 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 S(0.016)QT(0.984)PPGVATPPIPK;SQT(1)PPGVATPPIPK 203.05 3.1038e-10 146565000.0 240640.0 205575.0 254250.0 366280.0 354870.0 310910.0 250560.0 305890.0 246270.0 278230.0 True False 317158.51437705866 272023.09851176816 250878.47887600143 281839.80496958824 305602.42600208265 291468.748550422 272859.35460096307 258621.72915292022 259287.32942983034 268489.25238662044 1.1812708015602622 1.0131619649342947 0.9344079014184904 1.0497247188268943 1.1382296434049426 1.085588141646398 1.0162766374277423 0.9632479767961395 0.9657270342295137 1.0 18.03450481278209 -7.525303405264369 4.083875670444165 0.9744506382505251 1.060769692675668 0.2904584462809858 0.06356494722846383 0.3163129219301795 12.36479525724495 0.03300446778891017 0.019427825043391033 2.983297709904715e-08 7.525303405264369 0.08631905442514287 SQT(ph)PPGVATPPIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SQTPPGVATPPIPK 14 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 S(0.062)QT(0.925)PPGVAT(0.013)PPIPK;S(0.01)QT(0.987)PPGVAT(0.003)PPIPK;S(0.003)QT(0.997)PPGVATPPIPK 161.48 6.9103e-05 95883000.0 195689.0 202382.0 178408.0 242270.0 250020.0 225095.0 220808.0 201749.0 199582.0 178426.0 True False 228815.28266607187 222473.14746395752 182661.92333610746 228696.3973499377 201030.3757835876 213290.62194289936 199891.46772851824 196453.30252073464 202500.50917795184 210773.221380561 1.0855993999965254 1.0555095472126972 0.8666277534673285 1.0850353562562653 0.9537756953508708 1.0119436451454764 0.9483722192944272 0.9320600654768612 0.960750648737904 1.0 17.685332059459675 -5.023433819771256 24.476909249259926 0.9709673394484373 1.0780769943032176 0.3651235530790292 0.053759696868971245 493.80601806697837 515789.9766697836 0.01300240039827131 0.03492975625031217 9.474715545330617e-06 5.023433819771256 0.1071096548547803 SQT(ph)PPGVATPPIPK ddPTM_PC-9_Lapatinib_30min_R1 4 SQTPPGVATPPIPK 14 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 S(0.044)QT(0.881)PPGVAT(0.075)PPIPK;S(0.017)QT(0.982)PPGVATPPIPK;S(0.005)QT(0.995)PPGVATPPIPK;S(0.004)QT(0.995)PPGVATPPIPK 181.51 7.477800000000001e-05 144730800.0 454693.0 395345.0 435801.0 389100.0 424902.0 409034.0 347980.0 377727.0 412594.0 307822.0 True False 448208.9944395156 394429.60294242506 399971.1240205088 417715.71199954906 399910.0997494736 391540.5693248247 365996.70172078325 395277.5753802083 366123.31891256577 361028.6225529668 1.2414777290234336 1.092516156068922 1.1078654129751961 1.1570154993410962 1.1076963840749288 1.084513927333785 1.0137609010961106 1.0948649239637969 1.014111613432676 1.0 18.461753693760585 -1.5228787452808346 0.15427251231579905 0.9779638755063179 1.7730226399928695 0.6744861662822677 0.039437914166419785 42.18527926031762 0.4252372597745159 0.13094055342706104 7.551884328361838 0.02999999999996567 1.5228787452808346 0.7950587644865516 SQT(ph)PPRR ddPTM_PC-9_AZD4547_30min_R2 1 SQTPPRR 7 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.09)QT(0.91)PPRR 67.207 0.044387 4867300.0 24241.0 21214.0 24191.0 25764.0 25434.0 25837.0 26969.0 23820.0 31927.0 28603.0 True False 31949.13375587707 28071.01063761958 23870.21153388139 19824.507849832025 21902.92812279705 24221.408305610115 29369.188754124276 20139.16632914634 33614.59603973768 27601.617676075613 1.1575094666849826 1.0170059946142513 0.8648120488449301 0.7182371729978496 0.7935378418701146 0.8775358238008137 1.06403867696424 0.7296371743675901 1.2178487664827689 1.0 14.752465202526105 -9.447133509810902 10.856361457856188 1.0000006242513815 0.9230968715684756 0.0056187677932864055 0.1649739623546556 0.0 0.0 0.15988747523253655 0.038778408741004466 3.57163023038046e-10 9.447133509810902 -0.07690375268290583 SQTGDVS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 SQTGDVSPK 9 0 H0YBF7;A0A0A0MRE5;Q9ULH1;Q9ULH1-2;H0YBM4 H0YBF7 ASAP1 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 1 SQTGDVS(1)PK 92.24700000000001 0.0071763999999999994 14876000.0 32943.0 31206.0 24128.0 40550.0 41457.0 27929.0 38147.0 42462.0 38445.0 34688.0 True False 43418.188743032835 41292.72923340985 23808.04695504485 31201.82399125482 35701.411149909436 26182.59521490051 41542.00909946896 35900.47357968982 40477.12421297693 33473.583678205454 1.2970881504779628 1.2335915278857763 0.7112488218746114 0.9321327614996368 1.066554794166079 0.7821867974043041 1.2410385902754963 1.0725016456204688 1.2092258959213698 1.0 15.030735393615636 -9.643661500838478 9.901529229314674 1.0000013514327135 1.0492929968837614 0.005978948966515296 0.18918139688954325 0.0 0.0 0.1893110188782446 0.0459146662899001 2.2716347266872456e-10 9.643661500838478 0.049291645451047916 SQTGDVS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQTGDVSPK 9 0 H0YBF7;A0A0A0MRE5;Q9ULH1;Q9ULH1-2;H0YBM4 H0YBF7 ASAP1 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 1 SQTGDVS(1)PK 67.87899999999999 0.044562 16291000.0 23940.0 23642.0 21660.0 28848.0 31496.0 26324.0 25648.0 33138.0 25652.0 23552.0 True False 27992.56916344695 25989.02151546522 22176.456546007445 27231.740086477905 25324.584895927783 24943.523099246475 23218.435764560265 32268.16261261327 26027.111971183847 27821.79116247057 1.0061382820386757 0.934124670970947 0.7970894618719502 0.9787917653271513 0.9102427930696524 0.8965462702808777 0.8345413718682544 1.1598161464219638 0.9354937580831386 1.0 14.76392768289581 -7.7467355723123985 24.999648206115683 1.0357412740169978 0.9072776540819546 0.34830725783686367 0.07738607921474329 237.46745564175336 403747.5238642249 0.03531977257706107 0.020278996532383492 1.791696427273896e-08 7.7467355723123985 -0.12846361993504318 SQTGDVS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 SQTGDVSPK 9 0 H0YBF7;A0A0A0MRE5;Q9ULH1;Q9ULH1-2;H0YBM4 H0YBF7 ASAP1 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 1 SQTGDVS(1)PK;S(0.003)QT(0.006)GDVS(0.991)PK 85.522 0.012371 31772000.0 73428.0 70330.0 55698.0 60240.0 74540.0 54772.0 66347.0 61413.0 60665.0 57834.0 True False 72380.90325495401 70167.15520606242 51118.72544049756 64670.25055474902 70155.70375127856 52429.52923976813 69782.12302163582 64266.472179179014 53832.268869229374 67830.52984103904 1.0670844444909804 1.034447989282986 0.7536241506633427 0.9534091906152563 1.0342791647903764 0.7729488382685027 1.028771604544006 0.9474564378280341 0.7936289012541312 1.0 16.049647141651718 -5.028238173434585 24.6874060114188 0.9125763959054305 1.0589254408586921 0.245948545170127 0.09890220341807474 696.5214844322367 608940.8829323604 0.024320645431252366 0.06468687237052909 9.370479751969916e-06 5.028238173434585 0.14634904495326162 SQTTS(ph)LENGVFPR ddPTM_PC-9_AZD4547_30min_R2 2 SQTTSLENGVFPR 13 0 J3KNG8;Q8TF40;Q8TF40-2;Q8TF40-3;A0A087WX11 J3KNG8 FNIP1 Folliculin-interacting protein 1 1 SQTT(0.083)S(0.917)LENGVFPR;SQT(0.373)T(0.143)S(0.484)LENGVFPR 161.49 6.0947e-05 9630200.0 40902.0 36634.0 63038.0 82797.0 72752.0 63211.0 64646.0 85655.0 64591.0 59594.0 True False 53907.98518554866 48475.224083084526 62202.07493170247 63709.4308508982 62651.6405909307 59258.40617741694 70399.36876410387 72418.98790608854 68005.14839485992 57507.6321990019 0.9374057516227262 0.8429354892466927 1.0816316470213156 1.1078430534304617 1.089449142578645 1.030444202125321 1.2241743586397515 1.2592935083031542 1.1825412696445572 1.0 15.811465817431742 -5.366137180567577 0.7943095521635355 1.160190897683684 0.8230242041621559 0.5139325167994393 0.08524690257121781 1.017103981642214 0.850783942450501 0.03750691479691953 0.2625586041814291 4.303906415567919e-06 5.366137180567577 -0.33716669352152817 SQTTS(ph)LENGVFPR ddPTM_PC-9_Lapatinib_30min_R1 2 SQTTSLENGVFPR 13 0 J3KNG8;Q8TF40;Q8TF40-2;Q8TF40-3;A0A087WX11 J3KNG8 FNIP1 Folliculin-interacting protein 1 1 SQT(0.001)T(0.082)S(0.917)LENGVFPR;SQT(0.189)T(0.189)S(0.622)LENGVFPR 141.59 7.7815e-05 8218400.0 43673.0 41688.0 39995.0 45622.0 50675.0 44390.0 40161.0 43593.0 47446.0 39368.0 True False 43050.21501135267 41591.47399730311 36706.76548516463 48977.19407053059 47694.39613088325 42491.54317814405 42240.34007071779 45618.489924070636 42102.13185147046 46172.70634543737 0.9323736557540285 0.9007805105929867 0.7949883901226393 1.0607390804453105 1.03295647809902 0.9202740437228653 0.9148335329252764 0.9879968824608112 0.9118402446780305 1.0 15.494752675868133 -5.759730031529513 24.999804581913665 0.9725825661294445 0.8785208383367623 0.3888084466473041 0.05704382796185175 52.2671798703975 764399.0421706536 0.016585668202203658 0.026913711764217887 1.738881425670915e-06 5.759730031529513 -0.09406172779268218 SQTTTERDS(ph)DTDVEEEELPVENR ddPTM_PC-9_AZD4547_30min_R2 1 SQTTTERDSDTDVEEEELPVENR 23 1 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 S(0.009)QT(0.026)T(0.026)T(0.026)ERDS(0.912)DT(0.002)DVEEEELPVENR 85.884 0.00011991 0.0 5578.4 4625.2 6480.6 9538.4 7586.6 4622.1 3489.9 5547.7 3757.7 4018.6 True False 7352.215162071896 6120.205449284341 6394.66300965118 7339.46924681097 6533.3315442483345 4333.0793563246725 3800.4943391678707 4690.4304384636935 3956.324350503407 3877.9100371666427 1.895922053788468 1.578222648443905 1.6489972558320043 1.8926352536464415 1.6847558302362913 1.1173749042127328 0.9800367473054288 1.2095253354280262 1.0202207664915448 1.0 11.921063619710967 -6.759841267601121 4.740210052939399 1.067070905598493 1.740184689089617 0.9073340947527263 0.10806192640743081 0.05446797874494967 3.1510161269549064 0.037579059867908486 0.03523237152278952 1.7384361020995527e-07 6.759841267601121 0.673113783491124 SQTTTERDS(ph)DTDVEEEELPVENR ddPTM_PC-9_Lapatinib_30min_R1 2 SQTTTERDSDTDVEEEELPVENR 23 1 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 S(0.001)QT(0.011)T(0.011)T(0.016)ERDS(0.957)DT(0.004)DVEEEELPVENR;S(0.003)QT(0.016)T(0.011)T(0.016)ERDS(0.953)DT(0.001)DVEEEELPVENR 135.06 6.8362e-09 0.0 11222.5 7759.5 11018.5 5112.4 7564.6 7800.8 7993.5 10187.1 10069.8 8062.5 True False 11062.465092045557 7741.533354492256 10112.601462639992 5488.382950466452 7119.665100575821 7467.17796855297 8407.364317504118 10660.429855836946 8935.633084305047 9456.092382394041 1.1698770109990004 0.818682077271785 1.0694271009310654 0.5804070781589523 0.7529183105097059 0.7896684662742763 0.8890949852771625 1.127361009679349 0.9449604258247288 1.0 13.207028414823334 -7.605096411665425 7.155607265085723 1.0259568348464185 0.8518336936510105 0.1680643148646237 0.15952797904152238 0.38820677980797846 28.344907119116453 0.07699684940777109 0.04412811982241265 2.482581920703473e-08 7.605096411665425 -0.17412314119540806 SQVEEELFSVR ddPTM_PC-9_AZD4547_30min_R2 2 SQVEEELFSVR 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 ; 132.03 0.00059431 3579400.0 13778.7 19734.8 22500.0 30123.0 24513.0 21121.0 20810.2 28211.0 22695.9 20948.8 False True 18160.039985235915 26113.68816495215 22201.63529876115 23178.6077457107 21109.79307517983 19800.300531129436 22662.267485300785 23851.638174288288 23895.55893940183 20215.38888831847 0.898327511064096 1.291772733595149 1.0982541776176484 1.146582332586465 1.0442437289632451 0.9794667142204277 1.1210403920745868 1.179875307176061 1.182047947304638 1.0 14.303166336898952 -10.96731993112887 3.4625378810462024 0.9987135077093602 1.1084137623734887 0.08070035973950129 0.10523788010601559 75614190.81971818 52028838.85012363 856545.8303640031 0.025683973340461325 1.0781521886964732e-11 10.96731993112887 0.10970025466412847 SQVEEELFSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SQVEEELFSVR 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 103.43 0.010798 0.0 5173.0 4577.9 5794.3 5352.5 7937.4 5270.4 5665.7 5972.9 5108.4 3870.2 False True 6048.686728592774 5032.363657712897 5932.458087005119 5052.616778039132 6382.123449102657 4994.01094599106 5129.003879884166 5816.117703810665 5183.10068585668 4571.836623513659 1.323032126188291 1.1007312973151047 1.2976093801107358 1.105161271960758 1.395964898718912 1.092342390431472 1.121869459093291 1.2721621927383575 1.1337020792036172 1.0 12.158558133827327 -14.522878744814706 0.19005679855414526 0.11090276481958689 1.2406548705505913 0.2927065593502195 0.10187459528825721 176.6541791806913 1.7229262601405484 59.2421190740337 0.2616311312691668 3.0000000032164666e-15 14.522878744814706 1.1297521057310045 SQVEEELFSVR ddPTM_PC-9_Lapatinib_30min_R1 1 SQVEEELFSVR 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 184.44 0.0057366000000000006 6123500.0 21820.0 21698.0 18008.0 14503.0 16567.0 15055.0 12465.0 15250.0 20309.0 11179.0 False True 21508.842798702077 21647.759614121154 16527.45175289023 15569.59900058973 15592.56163197519 14411.132744919103 13110.376708286578 15958.570672862097 18021.586556749025 13111.275254918819 1.6404844212718996 1.65107963895425 1.2605525726179685 1.1874969213805993 1.1892482865940515 1.0991404317831426 0.9999314676402736 1.2171638809028198 1.3745105801198139 1.0 13.67852039420683 -5.337982217202984 2.8007271491860424 1.1556475608855683 1.6633615299013278 0.7784798478692538 0.1035445145455132 0.12426848697766354 1.874326385208876 0.029454974899303144 0.08015893421818028 4.592168157288593e-06 5.337982217202984 0.5077139690157595 SQVNGEAGS(ph)YEMTNQHVK ddPTM_PC-9_AZD4547_30min_R2 1 SQVNGEAGSYEMTNQHVK 18 0 Q05D32;H0YMH7;Q05D32-2 Q05D32 CTDSPL2 CTD small phosphatase-like protein 2 1 S(0.111)QVNGEAGS(0.461)Y(0.318)EMT(0.11)NQHVK 89.44 0.0012680999999999999 4584600.0 10633.0 12246.0 14447.0 22603.0 19430.0 17179.0 14039.0 23698.0 14290.0 18295.0 True False 14014.072819860614 16204.280016417892 14255.423340497897 17392.22756286887 16732.479886213197 16104.794414292533 15288.443802853295 20036.018625865225 15045.34022638679 17654.497618564605 0.7937961828562089 0.9178556290029043 0.8074669496971464 0.9851442923292281 0.9477743432709261 0.9122204869402526 0.8659801107439453 1.1348959941401182 0.8522100459299304 1.0 14.107748147488214 -1.946853098214796 0.27135143723159366 0.9867511226244395 8.003323839244535e-14 0.26049020403406453 0.08325750732104761 56.032557957156975 0.9646497448627808 0.09333534446217492 24.80664015661809 0.011301781371432585 1.946853098214796 -0.9867511226243595 SQVS(ph)SPCSR ddPTM_PC-9_AZD4547_30min_R2 1 SQVSSPCSR 9 0 H0YCY5;E9PNY0;E9PM53;E5KP25;Q9UIF7-6;Q9UIF7-5;Q9UIF7-4;Q9UIF7-3;Q9UIF7-2;Q9UIF7 H0YCY5 MUTYH A/G-specific adenine DNA glycosylase 1 SQVS(0.5)S(0.5)PCSR 100.69 0.0037398 7308400.0 16481.0 18732.0 27137.0 33076.0 31611.0 31302.0 26077.0 35895.0 25540.0 32879.0 True False 21721.61517390414 24786.752675774944 26777.145648999198 25450.839219105877 27222.35829557827 29344.68099168663 28397.80248215722 30348.252535042306 26889.992259056617 31727.91621758874 0.6846215498344802 0.7812285088559998 0.8439616855189177 0.8021591788305628 0.8579938912120311 0.9248852269541441 0.8950415239187555 0.9565157802017391 0.8475183833267259 1.0 14.953465152577158 -2.6428340722784696 0.2421089832058018 0.9673955916031595 3.325180264064033e-14 0.7913129906138656 0.03958172165795694 13.09588895695312 0.2816131896317112 0.053654861494124545 4.565254065528403 0.002275966826706238 2.6428340722784696 -0.9673955916031262 SQVS(ph)SPCSR ddPTM_PC-9_Lapatinib_30min_R1 1 SQVSSPCSR 9 0 H0YCY5;E9PNY0;E9PM53;E5KP25;Q9UIF7-6;Q9UIF7-5;Q9UIF7-4;Q9UIF7-3;Q9UIF7-2;Q9UIF7 H0YCY5 MUTYH A/G-specific adenine DNA glycosylase 1 SQVS(0.5)S(0.5)PCSR 81.525 0.017105000000000002 5477700.0 14802.0 16407.0 19384.0 14835.0 17980.0 16614.0 16763.0 15286.0 18743.0 12051.0 True False 14590.920765645642 16369.010599543071 17790.322344403823 15926.01538810927 16922.451750040076 15903.457949125595 17630.90611801106 15996.24336428656 16631.96596746008 14133.999293051862 1.032327826195548 1.158130141381139 1.2586899132752452 1.1267876174253346 1.1972868682934625 1.1251916474159993 1.2474109947549128 1.1317563438785623 1.1767345973786907 1.0 13.786882121504616 -10.474850847493096 5.505809957210617 0.9999997200930305 1.1649470993066902 0.37774178202736086 0.06208496256460646 2.061512005449151e-07 3.9314799041757365e-08 0.058105389704535625 0.014092603070550134 3.3508049821853706e-11 10.474850847493096 0.16494737921365965 SQVVAGTNYFIK ddPTM_PC-9_Lapatinib_30min_R1 1 SQVVAGTNYFIK 12 0 P04080;A0A1W2PS52 P04080 CSTB Cystatin-B 0 101.89 0.011886 4481700.0 38539.0 33468.0 30541.0 32341.0 37200.0 32941.0 27919.0 25816.0 30397.0 31492.0 False True 37989.42679281297 33390.506902267785 28030.036871669294 34719.465026413345 35011.96913801396 31532.190219221506 29364.509211283857 27015.5056059415 26973.36976539956 36935.35023954768 1.0285384204137493 0.9040257283526626 0.7588945736233136 0.9400063841614332 0.9479257381056508 0.8537130422404695 0.7950245231421273 0.7314268155230667 0.7302860157128939 1.0 15.17271463762475 -7.060370924169291 3.506033747459809 0.7925737414409034 0.907736311142864 0.18732020368905045 0.09502410126644795 0.36976985455163064 8.986414551723835 0.03782356713279336 0.029631677193250563 8.702200310624478e-08 7.060370924169291 0.1151625697019606 SQWESPSPTPS(ph)YR ddPTM_PC-9_Lapatinib_30min_R1 1 SQWESPSPTPSYR 13 0 Q92620 Q92620 DHX38 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 1 SQWES(0.008)PS(0.029)PT(0.209)PS(0.753)YR 110.25 0.00069697 4385900.0 35037.0 29771.0 53465.0 31093.0 32405.0 39406.0 31971.0 34608.0 41881.0 26803.0 True False 34537.3659550011 29702.067078624794 49069.31408086828 33379.682943207394 30499.00161068124 37720.6972398726 33626.30194469558 36216.014022715484 37163.92075351843 31435.862837247445 1.0986613007510255 0.9448465668781222 1.5609342213673063 1.061834475993984 0.9701976932710069 1.1999256211023557 1.0696796241537467 1.1520604416114253 1.182214114685727 1.0 14.940123741645758 SRAKCDVDET(ph)VS(ph)SAT(ph)LS(ph)EET(ph)EK ddPTM_PC-9_Lapatinib_30min_R1 1 SRAKCDVDETVSSATLSEETEK 22 2 A0A0A0MTH9;O14981-2;O14981 A0A0A0MTH9 BTAF1 TATA-binding protein-associated factor 172 5 S(0.005)RAKCDVDET(0.967)VS(0.883)S(0.379)AT(0.883)LS(0.906)EET(0.976)EK 50.397 0.038055 0.0 6579.1 4594.1 8584.4 5249.4 6099.9 7360.3 6586.4 7674.5 7355.7 6875.0 True False 6485.280827540822 4583.462643710661 7878.6237687422745 5635.458387485057 5741.115874864821 7045.517126697315 6927.411564497293 8031.085287139684 6527.223607045094 8063.334589638332 0.8042926602443903 0.56843264939056 0.9770925020110889 0.6988992363936899 0.7120026846265758 0.873772140839976 0.8591249051477114 0.9960005005199599 0.8094943270037195 1.0 12.97716087292474 -6.898416167594058 4.115126109150834 0.9104957989728288 0.7517778115721769 0.3383841259152507 0.10957230044680578 0.26888806335224363 8.362549151072878 0.03883013499602859 0.03396076099577357 1.263524980072805e-07 6.898416167594058 -0.1587179874006519 SRAPTSVT(ph)PVAPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRAPTSVTPVAPGK 14 1 Q8IZD4;Q8IZD4-2;F5GZK9 Q8IZD4 DCP1B mRNA-decapping enzyme 1B 1 S(0.009)RAPT(0.006)S(0.006)VT(0.979)PVAPGK 78.22800000000001 0.010234 2008800.0 26546.0 15154.0 21941.0 25962.0 32353.0 31406.0 26169.0 25545.0 22933.0 18430.0 True False 31039.713492600793 16658.388970703 22464.15665170586 24507.43330993965 26013.661897953774 29759.014072896774 23690.08287284692 24874.470817164773 23268.35174002649 21771.213108200274 1.4257227348029347 0.7651566721575338 1.0318284305087522 1.1256806494034437 1.1948650618901688 1.366897376136006 1.0881379349469456 1.1425394944021579 1.0687668906820038 1.0 14.410134177356873 -4.47176207281935 20.524955745012154 1.1027187405631165 5.042982107348931 0.32343260390362305 0.14535621470017074 139.33655880923155 61875.72035572712 0.03686467464835213 2523.6032479031833 3.374721413199145e-05 4.47176207281935 3.9402633667858145 SRAPTSVT(ph)PVAPGK ddPTM_PC-9_Lapatinib_30min_R1 1 SRAPTSVTPVAPGK 14 1 Q8IZD4;Q8IZD4-2;F5GZK9 Q8IZD4 DCP1B mRNA-decapping enzyme 1B 1 S(0.021)RAPT(0.015)S(0.051)VT(0.913)PVAPGK 61.126999999999995 0.038359 3167000.0 51418.0 36388.0 43970.0 39816.0 36501.0 32494.0 26762.0 20653.0 29942.0 21333.0 True False 50684.7698910936 36303.745821672055 40354.95632910833 42744.201462282355 34354.08294372707 31104.307367213612 28147.605412528315 21612.613777483344 26569.61665676199 25020.38062556428 2.0257393622264495 1.45096696828741 1.6128833902660988 1.7083753481595307 1.3730439779411745 1.2431588404947425 1.1249870988680655 0.8638003594318189 1.061918963359606 1.0 14.610816116392797 -6.734643640773322 0.9461408813540949 0.9600667815350704 1.7179084215000224 0.8183602451689331 0.14569868925386364 0.2243857885572593 0.43454311312812216 0.08412682599267783 0.07943285485069658 1.8422830620917743e-07 6.734643640773322 0.757841639964952 SRDAT(ph)PPVSPINMEDQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRDATPPVSPINMEDQER 18 1 P17275 P17275 JUNB Transcription factor jun-B 1 S(0.036)RDAT(0.963)PPVS(0.001)PINMEDQER 62.739 0.012896000000000001 4741600.0 6202.6 4477.7 7926.4 7951.8 7980.6 8537.5 9128.1 9032.0 8600.8 7576.6 True False 7252.577673065832 4922.216463911624 8115.395437039394 7506.286426083434 6416.858719216454 8089.778470590212 8263.420286278959 8794.919570195041 8726.570428885003 8950.177603667398 0.8103277939528303 0.5499574066434962 0.9067301003852766 0.8386745781455421 0.716953227451833 0.9038679262940401 0.9232688614908563 0.9826530779223042 0.9750164538979907 1.0 13.127700595573947 -6.820900585610545 0.5176941415014017 1.017433916146472 0.7043692300393481 0.5343147465986822 0.09040056183682121 0.773369894322862 0.44429621977733497 0.0813128447334982 0.09945695463248214 1.5104258663169305e-07 6.820900585610545 -0.3130646861071239 SRDDLYDQDDSRDFPR ddPTM_PC-9_Lapatinib_30min_R1 1 SRDDLYDQDDSRDFPR 16 2 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 0 88.163 0.016468 4021800.0 53296.0 46426.0 45176.0 40440.0 38898.0 37390.0 31645.0 31479.0 37181.0 32050.0 False True 52535.98926671059 46318.50344940496 41461.803664403 43414.09250388531 36610.096116410416 35790.916860347075 33283.4232598258 32941.629259739384 32993.28424671255 37589.7997960594 1.3976129043448118 1.2322093679855302 1.1030067701703883 1.1549434351719128 0.9739369806446352 0.952144386363534 0.8854376304317257 0.8763448977771015 0.877719073411274 1.0 15.198053611131458 -5.050659510472412 0.5351717749480313 0.8896057214449665 1.6148280568070597 0.8964936842242541 0.05310094351012014 0.9411132950279618 0.25305103143553587 0.03272104585090927 0.41169101219094617 8.898985303199444e-06 5.050659510472412 0.7252223353620931 SRDESASET(ph)STPSEHSAAPSPQVEVR ddPTM_PC-9_AZD4547_30min_R2 1 SRDESASETSTPSEHSAAPSPQVEVR 26 1 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 S(0.026)RDES(0.083)AS(0.225)ET(0.438)S(0.123)T(0.104)PS(0.001)EHSAAPSPQVEVR 55.442 0.040618 0.0 7454.2 8041.8 9623.6 15472.0 11265.0 8639.4 8686.5 10341.0 7978.0 11070.0 True False 9824.480543008083 10641.154584029842 9495.984776051471 11905.169440017124 9701.049198054125 8099.176952257924 9459.581672019734 8743.036062539975 8399.700792590194 10682.442669445756 0.9196848367937754 0.9961349583898066 0.8889338393747876 1.114461346379948 0.9081302374597673 0.7581764960390037 0.8855260884363381 0.8184491443653679 0.7863089980922876 1.0 13.382953953930679 -6.522235131782618 24.994756951749817 0.8397591044542976 0.9790815849278087 0.3531119657934546 0.08246914499832247 23.481981060896395 911980.1008927721 0.025446998626159744 0.025738197836301296 3.004449220538657e-07 6.522235131782618 0.13932248047351115 SRDPHYDDFR ddPTM_PC-9_AZD4547_30min_R2 2 SRDPHYDDFR 10 1 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 0 ; 71.03 0.015424 7260400.0 3862.4 5077.2 8295.3 12549.0 10158.4 7225.9 7946.1 9469.7 8157.6 8581.099999999999 False True 5090.562857089213 6718.305609942591 8185.298901947262 9656.021930117295 8748.081506747722 6774.063330708213 8653.287506364599 8006.3754570578085 8588.794081929525 8280.67830088356 0.6147519167054278 0.8113231025078874 0.9884816925050548 1.1660906968318023 1.0564450385440394 0.8180565751461943 1.0449974255661256 0.9668743508854242 1.0372090026747072 1.0 13.015533233695896 -4.987393587587665 2.3118657704354666 1.010789257157221 0.5961137858369148 0.7014978653580366 0.08248871645028254 0.2274308735658981 1.987830173390305 0.0235498948449647 0.16145362405215838 1.0294527365454432e-05 4.987393587587665 -0.41467547132030624 SRDPHYDDFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRDPHYDDFR 10 1 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 0 64.439 0.023166 2601400.0 3166.5 3151.3 5496.1 3621.1 5956.5 4763.6 3654.0 2958.1 3554.0 3832.2 False True 3702.525908774218 3464.140237783841 5627.147868075323 3418.2215067645966 4789.366584093025 4513.788430161469 3307.866667330913 2880.4530093660264 3605.97052649257 4526.947524321489 0.8178857583133046 0.7652265061992419 1.243033597770439 0.7550830859867166 1.0579682133185027 0.9970931639721198 0.7307057679725821 0.6362903466166766 0.7965567321289068 1.0 12.144322867846041 -7.266355794295881 24.400949481221804 0.7605790633983607 0.9422810187093508 0.15724615309387047 0.16237686042461016 466.1092488048396 2313359.4501305637 0.06504332027228231 0.0454486981370477 5.415570398286429e-08 7.266355794295881 0.1817019553109901 SRDPQLCR ddPTM_PC-9_AZD4547_30min_R2 2 SRDPQLCR 8 1 I3L4S2;Q8TAT6;Q8TAT6-2 I3L4S2 NPLOC4 Nuclear protein localization protein 4 homolog 0 ; 148.99 0.0010504000000000002 3880400.0 9311.099999999999 6995.1 12594.4 16846.5 15064.5 13231.1 9496.5 14098.0 11657.2 10877.9 False True 12271.836117088695 9256.12927836394 12427.390026965226 12962.799700830426 12973.054207198089 12403.75722538832 10341.67010284182 11919.4780398113 12273.375793354524 10497.068031975068 1.169072742951414 0.8817823462864954 1.183891538962138 1.2348971790355654 1.235874071472237 1.1816401672929333 0.9851960634474415 1.1355054576671728 1.1692194197435564 1.0 13.357698800163444 -10.548939925678742 14.691780873605662 1.0000000163042049 1.1285301113081632 0.11912309315281988 0.1065360660419235 0.0 0.0 0.10853954236090128 0.026324705747658737 2.8252707569585698e-11 10.548939925678742 0.1285300950039583 SRDPQLCR ddPTM_PC-9_Lapatinib_30min_R1 2 SRDPQLCR 8 1 I3L4S2;Q8TAT6;Q8TAT6-2 I3L4S2 NPLOC4 Nuclear protein localization protein 4 homolog 0 ; 136.27 0.0045236 4446100.0 16270.099999999999 18026.7 18423.7 14149.5 19431.8 17773.4 17015.8 14066.0 14255.9 13213.5 False True 16038.085390429076 17984.96028370715 16908.974503538633 15190.10143134831 18288.85972838871 17013.273113819003 17896.79486505117 14719.557710457579 12650.250420717834 15497.435869117966 1.0348863854560917 1.1605119992492514 1.0910820761796773 0.9801686911070181 1.1801216590180101 1.0978121321167507 1.1548229665989103 0.9498060088630224 0.8162802238740815 1.0 13.919741913441118 -7.8882014383867585 5.228260115583402 0.9007282601051856 1.0997965909949472 0.5775826349509604 0.0700773934403046 0.1346841034232871 5.561679770966818 0.03841405903325081 0.017909560920148858 1.2935956950461578e-08 7.8882014383867585 0.1990683308897616 SRDS(ph)FLK ddPTM_PC-9_AZD4547_30min_R2 1 SRDSFLK 7 1 P46778;M0R181 P46778 RPL21 60S ribosomal protein L21 1 S(0.015)RDS(0.985)FLK 79.986 0.013682 0.0 14243.0 19647.0 14533.0 22302.0 20997.0 18387.0 12962.0 23008.0 15947.0 17318.0 True False 18771.97772719595 25997.508531974727 14340.282924306492 17160.618462465223 18081.9289846021 17237.257983328298 14115.592889278756 19452.642271242596 16789.925863554257 16711.702091188956 1.1232834109155914 1.5556469586471147 0.8580982862222774 1.0268623967102042 1.0819920607689373 1.0314483760703486 0.8446532143916706 1.1640132264862935 1.0046807782916705 1.0 14.02857105929574 -5.26860608289771 24.997075777786588 1.0065790819178204 1.339465189468941 0.5130564654418334 0.13163781108622463 371.44674259577664 1295589.6050271369 0.03242118647051756 0.06976615962959735 5.387582295749087e-06 5.26860608289771 0.3328861075511207 SRDS(ph)FLK ddPTM_PC-9_Lapatinib_30min_R1 1 SRDSFLK 7 1 P46778;M0R181 P46778 RPL21 60S ribosomal protein L21 1 SRDS(1)FLK 74.173 0.020819 0.0 18328.0 24675.0 22748.0 15848.0 24923.0 17685.0 25335.0 25604.0 23608.0 24620.0 True False 18066.63935905644 24617.866553527485 20877.747249819357 17013.5147873782 23457.078140503276 16928.65377574855 26646.72233489293 26793.65531199745 20949.01843673892 28875.534195912092 0.6256729048363072 0.8525510346060589 0.7230254896124144 0.5892017329254051 0.8123513137922862 0.5862628778014135 0.9228131384203206 0.9279016322333744 0.7254937101632797 1.0 14.817560016109812 -7.2793357251067645 24.835171337759828 0.8880439383112176 0.7065602522328994 0.45567617655994896 0.10455510049582341 756.7026342057586 1050089.2971667727 0.04215420415550382 0.02848854749766282 5.256107934330809e-08 7.2793357251067645 -0.18148368607831822 SRDS(ph)GDENEPIQER ddPTM_PC-9_AZD4547_30min_R2 1 SRDSGDENEPIQER 14 1 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;Q8WX93-4;Q8WX93-7 Q8WX93-3 PALLD Palladin 1 S(0.004)RDS(0.996)GDENEPIQER 118.23 5.595100000000001e-05 11369000.0 12048.0 14197.0 22887.0 24837.0 24906.0 18415.0 13287.0 20452.0 17185.0 19434.0 True False 15879.013386032222 18785.902612533468 22583.503425899864 19111.21337782481 21448.23180885362 17263.507138901965 14469.517259670327 17291.61334020575 18093.36401612716 18753.621575249217 0.8467171699246152 1.0017213228471484 1.2042209199584828 1.019067879830077 1.1436847929767717 0.9205425773166989 0.7715585601219023 0.9220412852431124 0.9647930637571649 1.0 14.194881605778107 -6.8943957025081986 7.941582057165351 0.8994725975552345 1.0480339436645232 0.2670049736663541 0.10408505805199395 0.30440360707200187 20.66246785991191 0.03783038642442361 0.0333698741190448 1.2752763256908445e-07 6.8943957025081986 0.14856134610928873 SRDS(ph)GDENEPIQER ddPTM_PC-9_Lapatinib_30min_R1 1 SRDSGDENEPIQER 14 1 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;Q8WX93-4;Q8WX93-7 Q8WX93-3 PALLD Palladin 1 S(0.036)RDS(0.964)GDENEPIQER 163.44 0.00026685 13226000.0 15789.0 13697.0 13875.0 10633.0 14056.0 10609.0 8858.9 12143.0 13493.0 10854.0 True False 15563.845964652017 13665.285438041177 12734.251059048856 11414.986290648189 13229.25371515925 10155.277800786898 9317.570495069393 12707.208110200938 11973.276252410977 12730.099437954093 1.2226020731817115 1.0734625840626884 1.0003261263680616 0.8966926257162636 1.0392105560241702 0.7977375078869765 0.7319322634110436 0.9982017950555118 0.9405485252309428 1.0 13.63595606808039 -4.619252952385502 0.844492882218094 0.8996032410131696 1.4818654161467202 0.5445439646480064 0.08915230670830976 2.3718375390252135 1.0884896451087918 0.03398532439230247 1.373877875203667 2.4029628001281247e-05 4.619252952385502 0.5822621751335506 SREDLT(ph)AVVSVSTK ddPTM_PC-9_AZD4547_30min_R2 2 SREDLTAVVSVSTK 14 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(0.415)REDLT(0.585)AVVSVSTK;S(0.405)REDLT(0.595)AVVSVSTK 87.16 0.0044821999999999996 33784000.0 206725.0 264660.0 309810.0 401260.0 338910.0 397110.0 346780.0 373650.0 334750.0 342230.0 True False 272459.2498528807 350206.16929161886 305701.71697374235 308755.7064052011 291858.1965124297 372278.6489236681 377642.74819812406 315910.9781228186 352444.2015943301 330248.6318667053 0.8250125013776 1.060431854969709 0.925671410796728 0.9349189568477027 0.8837529314284314 1.1272678006851726 1.1435104093044295 0.9565852743648195 1.0672086651870925 1.0 18.33319305921487 -6.757163524958235 24.999996836456063 1.061488260118734 0.9339102852870302 0.4377077821221055 0.07504923057083887 111.34470371096802 651008.5975264141 0.025215818390331025 0.024368758899943607 1.7491879426481074e-07 6.757163524958235 -0.12757797483170386 SREDLT(ph)AVVSVSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SREDLTAVVSVSTK 14 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(0.193)REDLT(0.806)AVVS(0.001)VSTK 91.789 0.045342 7348700.0 17661.0 18502.0 22104.0 29785.0 33744.0 28074.0 32319.0 27849.0 28990.0 25657.0 True False 20650.658479349906 20338.756284541825 22631.043189886823 28116.243014272874 27132.105433330835 26601.75001854753 29257.51035070274 27117.993258454575 29413.923906308275 30308.41099929977 0.6813507471515748 0.6710598020137618 0.7466918404402554 0.9276712993935069 0.8952005248298132 0.8777019032493034 0.965326435337659 0.894734905735609 0.9704871663178858 1.0 14.887430596451535 -5.65981659578376 2.982621811623536 0.9277620612085745 0.6789395211758814 0.8953700730647668 0.03696586045934426 0.07265668899047573 1.2893622129796312 0.01028187572263997 0.019511232893320275 2.1886857191388663e-06 5.65981659578376 -0.2488225400326931 SREDS(ph)PELNPPPGIEDNR ddPTM_PC-9_AZD4547_30min_R2 2 SREDSPELNPPPGIEDNR 18 1 Q03164-2;Q03164;Q03164-3 Q03164-2 KMT2A Histone-lysine N-methyltransferase 2A;MLL cleavage product N320;MLL cleavage product C180 1 S(0.396)REDS(0.604)PELNPPPGIEDNR;S(0.36)REDS(0.64)PELNPPPGIEDNR 81.226 0.0082125 3300500.0 14570.9 16517.9 24469.0 32771.0 27706.0 21650.0 16651.7 26041.0 18193.1 23257.0 True False 19204.14310645227 21856.988149860288 24144.525072239412 25216.152256902875 23859.500140371754 20296.22207750354 18133.669041382742 22016.961812649017 19154.75012405022 22442.77950887987 0.855693614013087 0.9738984487733436 1.0758259716754877 1.1235752793866585 1.0631258989525487 0.9043542075291071 0.807995686728903 0.9810265169667433 0.8534927733203151 1.0 14.453963742454766 -6.773668341241722 24.359784197197897 0.9018518082469758 1.0249809584917229 0.2885213951478144 0.08490244815659938 208.39939124691736 415123.07399959705 0.031318844289028494 0.027830983600226167 1.683959563787932e-07 6.773668341241722 0.12312915024474713 SREDS(ph)PELNPPPGIEDNR ddPTM_PC-9_Lapatinib_30min_R1 1 SREDSPELNPPPGIEDNR 18 1 Q03164-2;Q03164;Q03164-3 Q03164-2 KMT2A Histone-lysine N-methyltransferase 2A;MLL cleavage product N320;MLL cleavage product C180 1 S(0.251)REDS(0.749)PELNPPPGIEDNR 91.27600000000001 0.0027909000000000002 0.0 11055.0 11508.0 13818.0 8836.8 10963.0 11033.0 10495.0 11910.0 11635.0 9220.9 True False 10897.35367276129 11481.353933049413 12681.937379022493 9486.687750700637 10318.177894087281 10561.144309179172 11038.379747570609 12463.38207959263 10324.543778018357 10814.720278923069 1.0076408258102862 1.0616413219143128 1.1726551452041218 0.8772013982820573 0.9540864329331287 0.9765527019466149 1.0206810220587428 1.1524460881233014 0.9546750643324522 1.0 13.400708730246532 -5.750487625187219 24.999825449998195 0.9962789201489519 1.0787452630932979 0.22614709376962872 0.07566019745852062 382.1281483698739 872285.4694540045 0.021845397515240218 0.037373817010351564 1.7762838811058396e-06 5.750487625187219 0.08246634294434596 SREQSSEAAETGVS(ph)ENEENPVR ddPTM_PC-9_Lapatinib_30min_R1 1 SREQSSEAAETGVSENEENPVR 22 1 Q29RF7 Q29RF7 PDS5A Sister chromatid cohesion protein PDS5 homolog A 1 SREQSSEAAET(0.001)GVS(0.999)ENEENPVR 89.882 9.7246e-05 7516000.0 12842.0 11603.0 11511.0 8421.5 10030.0 8723.5 8636.3 9033.6 10002.0 7221.0 True False 12658.870725065626 11576.133966386196 10564.61001374497 9040.845203300452 9440.055119738712 8350.416240471719 9083.445356259554 9453.334034778165 8875.469434270706 8469.140228622307 1.4947055289371294 1.3668605848871758 1.2474241456105324 1.0675044879698663 1.1146414942847565 0.9859815772385786 1.0725345325563438 1.1162094120049726 1.0479776216569385 1.0 13.047999801933646 -5.297351067291466 1.221909211865438 1.0546709048259422 1.5277274989037042 0.9289449223842349 0.04217504394134673 0.16874241795705128 0.3798566219040859 0.013469634306378125 0.08032711247386008 5.042535132312182e-06 5.297351067291466 0.473056594077762 SRES(ph)ASPTIPNLDLLEAHTK ddPTM_PC-9_AZD4547_30min_R2 1 SRESASPTIPNLDLLEAHTK 20 1 O75151 O75151 PHF2 Lysine-specific demethylase PHF2 1 S(0.159)RES(0.28)AS(0.28)PT(0.28)IPNLDLLEAHTK 104.67 6.5191e-05 6437900.0 13741.0 12718.0 16829.0 28445.0 24002.0 19060.0 14365.0 21328.0 15277.0 19120.0 True False 18110.352169444617 16828.844785954836 16605.836464126747 21887.44472086913 20669.736604677782 17868.175186938453 15643.457171307613 18032.24766868316 16084.51103138637 18450.61461967507 0.9815582051197573 0.9121021241216085 0.9000153548499615 1.1862718490433999 1.1202736077223314 0.9684325186589977 0.847855613147217 0.9773250398636706 0.8717601750911012 1.0 14.171381255129877 -6.999003718384996 24.994362765502114 0.9203168256439836 1.019387946569065 0.19845700845270176 0.09078933120962393 59.95375488436461 1504053.1474382032 0.03514989918536463 0.030751116625308963 1.0022966564795623e-07 6.999003718384996 0.0990711209250813 SRES(ph)ASPTIPNLDLLEAHTK ddPTM_PC-9_Lapatinib_30min_R1 1 SRESASPTIPNLDLLEAHTK 20 1 O75151 O75151 PHF2 Lysine-specific demethylase PHF2 1 S(0.266)RES(0.452)AS(0.141)PT(0.141)IPNLDLLEAHTK 101.61 0.00011075 6152900.0 75337.0 48745.0 61746.0 46397.0 50943.0 54305.0 50800.0 43059.0 63628.0 44110.0 True False 74262.68056488634 48632.13394738385 56669.48222645268 49809.190155854754 47946.632897791525 51982.50174113795 53430.17543369101 45059.678334607815 56461.544607456104 51734.35472711952 1.435461618427364 0.9400355760480866 1.0953936223881446 0.9627875020106208 0.9267851730381699 1.0047965614982022 1.0327793922532975 0.8709817407075382 1.0913742890052625 1.0 15.658835014717573 -4.757557702178795 24.998698703259354 0.9896351584207103 1.4354622590972135 0.797705362754038 0.06704038653473804 45.941909037759515 295832.53195088124 0.015768580034934348 0.11582249544229715 1.7476010534172208e-05 4.757557702178795 0.4458271006765032 SRES(ph)LNVDVVK ddPTM_PC-9_AZD4547_30min_R2 1 SRESLNVDVVK 11 1 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;G3V3H3;H0YJT3;F8W6L3;E7EVH7;G5E9S8;H0YJU9;H0YJL0;G3V2E7;Q07866-8;Q07866-2;Q07866-3;Q07866-5;Q07866-10;Q07866;H0YGB8 Q07866-6 KLC1 Kinesin light chain 1 1 S(0.059)RES(0.941)LNVDVVK 121.13 0.00037683 18155000.0 73246.0 87730.0 109020.0 133370.0 126220.0 143850.0 111930.0 142680.0 118160.0 136250.0 True False 96536.70438855568 116087.00684634503 107574.32356759753 102623.60704595942 108696.53171579166 134855.0367597639 121891.55316285852 120632.08446022651 124405.69637157912 131479.92897127251 0.7342314917864635 0.8829256887696468 0.8181805725731857 0.7805267910388207 0.826715777581087 1.0256701369927634 0.9270734637337004 0.9174942928862079 0.946195342094845 1.0 17.004483056588143 -6.666124657378348 7.132670745206429 0.9555151281284473 0.810122448073623 0.7367889354262108 0.04619872838756008 0.12403744915522696 7.983163401869447 0.015112356580550053 0.015075572753395163 2.1571251515451316e-07 6.666124657378348 -0.1453926800548243 SRES(ph)LNVDVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRESLNVDVVK 11 1 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;G3V3H3;H0YJT3;F8W6L3;E7EVH7;G5E9S8;H0YJU9;H0YJL0;G3V2E7;Q07866-8;Q07866-2;Q07866-3;Q07866-5;Q07866-10;Q07866;H0YGB8 Q07866-6 KLC1 Kinesin light chain 1 1 S(0.01)RES(0.99)LNVDVVK 92.26899999999999 0.0036514000000000004 20484000.0 28665.0 34835.0 44209.0 50454.0 46382.0 41899.0 52707.0 46661.0 48918.0 44149.0 True False 33517.418340443066 38293.18858350523 45263.110223566124 47627.22595407502 37293.7800559729 39701.742681025986 47714.21139436521 45436.198191416166 49633.33320623621 52152.8642167083 0.6426764635815541 0.7342490035520844 0.8678930851330904 0.9132235912522826 0.7150859423752421 0.7612571864903763 0.9148914850793358 0.8712119434633026 0.9516894987779999 1.0 15.670458866767545 -1.871727694623416 0.10579978012662054 1.0915867607697851 2.0987214168404212e-17 0.5832864676456078 0.07148932776248051 91.01187956559045 0.7324878532786778 0.8632617318778464 14.366961910814283 0.01343607147229479 1.871727694623416 -1.0915867607697851 SRES(ph)LNVDVVK ddPTM_PC-9_Lapatinib_30min_R1 2 SRESLNVDVVK 11 1 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;G3V3H3;H0YJT3;F8W6L3;E7EVH7;G5E9S8;H0YJU9;H0YJL0;G3V2E7;Q07866-8;Q07866-2;Q07866-3;Q07866-5;Q07866-10;Q07866;H0YGB8 Q07866-6 KLC1 Kinesin light chain 1 1 S(0.329)RES(0.671)LNVDVVK;S(0.387)RES(0.613)LNVDVVK 121.18 0.00037416 54799000.0 165510.0 153422.0 155283.0 130583.0 146763.0 163594.0 155215.0 146612.0 159476.0 146662.0 True False 163149.797049183 153066.76078521975 142516.23114971438 140186.50943211818 138130.68888715966 156597.46597624014 163251.27322717215 153424.12875341985 141514.13352327066 172012.33128516877 0.9484773320042206 0.8898592306818962 0.8285233394892219 0.8149794167937385 0.803027828616317 0.9103851148707864 0.9490672674886768 0.8919368024788138 0.822697608165446 1.0 17.392152467540157 -6.822833985676339 23.914169378752938 0.9102044236696334 0.8548868320328318 0.20207328825641635 0.05702980906775993 86.51350182011461 33696.952711866485 0.020986400527612175 0.018508276746146093 1.5037166701417205e-07 6.822833985676339 -0.05531759163680161 SRFLVRPNT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 SRFLVRPNTR 10 2 A0A494C0W1;Q5U4N7 A0A494C0W1 GDF5OS Protein GDF5OS, mitochondrial 1 SRFLVRPNT(1)R 58.699 0.035773 1929200.0 0.0 0.0 4961.8 9351.0 7455.0 2523.0 904.08 6857.5 600.55 3371.1 True False 0.0 0.0 4896.003290017475 7195.27142150983 6420.001932666979 2365.2364111566467 984.5413685649697 5797.8309446734265 632.2938469528758 3253.07881508298 0.0 0.0 1.5050367877092419 2.2118343361829345 1.9735156439802448 0.7270762700830272 0.3026490978331418 1.7822595990578651 0.19436782288250437 1.0 11.66759006085359 -3.2996060656998876 10.75126364959974 1.0164608483314979 0.7632219553573517 0.0 0.8065847566228901 0.0 0.0 0.19760792516943146 0.0 0.0005016420503950517 3.2996060656998876 -0.25323889297414615 SRFS(ph)GGFGAR ddPTM_PC-9_Lapatinib_30min_R1 1 SRFSGGFGAR 10 1 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A2R8YDT5;A0A0J9YVQ7 A0A2R8Y5G6 1 S(0.376)RFS(0.624)GGFGAR 58.486999999999995 0.036188 11085000.0 23783.0 19547.0 23450.0 17500.0 13600.0 17215.0 11120.0 16220.0 17222.0 15918.0 True False 23443.85005873196 19501.74012246411 21522.031519617714 18787.00837828866 12800.07473862876 16478.75458012503 11695.73918942213 16973.640414021185 15282.277004300142 18669.405090598248 1.2557363207324739 1.0445828363478502 1.1527968574882992 1.0062992520179252 0.6856177085725548 0.8826609364442786 0.6264655532763603 0.9091687888099319 0.8185733251883942 1.0 14.188388335687845 -6.028486349979951 4.164811721563093 0.809767858516662 1.1359432646199006 0.6403983802580584 0.11152361214166662 0.12732960360221462 5.012425711954904 0.03141855803838906 0.043869133549877384 9.365126543360401e-07 6.028486349979951 0.3261754061032386 SRFT(ph)PELQPK ddPTM_PC-9_Lapatinib_30min_R1 1 SRFTPELQPK 10 1 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 S(0.481)RFT(0.519)PELQPK 97.20299999999999 0.003774 9670500.0 41919.0 52126.0 53932.0 38968.0 39411.0 31995.0 34753.0 29382.0 36236.0 28084.0 True False 41321.22737299688 52005.30544961191 49497.91914354042 41833.83671343729 37092.92246500721 30626.648433987815 36552.340292265035 30747.194984264526 32154.72009800371 32938.281980422245 1.2545046337740768 1.578871219832372 1.5027474466628479 1.2700673562240543 1.1261340979184762 0.9298192435231318 1.1097221255799226 0.9334790139491778 0.976211209713844 1.0 15.007477687407778 -6.194347127217872 1.9283584205782827 0.99451507880747 1.4571305225351097 0.8159699759698429 0.0940507601410069 0.13118936192447944 0.9599727101514453 0.031326702647641494 0.0431205056348933 6.392237061508296e-07 6.194347127217872 0.46261544372763963 SRGS(ph)PSSYNSSSSSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRGSPSSYNSSSSSPR 16 1 Q9H201;I6L9I8 Q9H201 EPN3 Epsin-3 1 S(0.025)RGS(0.931)PS(0.042)S(0.002)YNSSSSSPR 68.168 0.011184999999999999 7699600.0 11221.0 8535.5 9058.3 9195.8 11870.0 10312.0 11854.0 8562.6 10501.0 7880.6 True False 13120.4936751478 9382.848030845673 9274.284225794056 8680.589139185855 9544.158709507969 9771.2205667615 10731.103304471992 8337.840822824624 10654.557259059791 9309.290397204726 1.4093978289781843 1.007901529601336 0.9962396520124475 0.9324651792785786 1.0252294538339641 1.0496203415993421 1.1527305354760649 0.8956473014665225 1.14450799195812 1.0 13.184455486876857 -4.760287523518902 24.999726171331236 1.0207799284257566 1.409398292448263 0.6979427608228349 0.07630775012267246 15.535462206254621 337033.4368596251 0.01829308771148469 0.1095622281578718 1.7366507030445667e-05 4.760287523518902 0.3886183640225065 SRGS(ph)PSSYNSSSSSPR ddPTM_PC-9_Lapatinib_30min_R1 2 SRGSPSSYNSSSSSPR 16 1 Q9H201;I6L9I8 Q9H201 EPN3 Epsin-3 1 S(0.074)RGS(0.903)PS(0.021)S(0.002)YNSSSSSPR;S(0.012)RGS(0.986)PS(0.002)SYNSSSSSPR 86.575 0.006798 6889600.0 7137.5 6982.9 7814.3 6598.9 6680.1 5093.3 6878.4 6596.3 6454.9 4918.5 True False 7035.717941142803 6966.731524078095 7171.83841807031 7084.205119285084 6287.189651581912 4875.471432062201 7234.529895730316 6902.788178977068 5727.881188889619 5768.656171510712 1.2196459161302848 1.2076870794422174 1.2432424822767913 1.2280511974819004 1.089888089124127 0.8451658908257308 1.2541100874513929 1.1966024622974447 0.9929316323579024 1.0 12.49401956185221 -6.286025548208823 5.903207654754836 1.0708861777831638 1.2251114357213635 0.3572683665188231 0.1059721572378995 0.22979954801609181 28.179487755577977 0.03426760257098639 0.04014721934266566 5.175763836279942e-07 6.286025548208823 0.15422525793819974 SRGS(ph)TNLFSK ddPTM_PC-9_AZD4547_30min_R2 2 SRGSTNLFSK 10 1 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;A2SY06 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 S(0.084)RGS(0.904)T(0.012)NLFSK;S(0.204)RGS(0.398)T(0.398)NLFSK 123.68 0.00020669 67903000.0 230978.0 274435.0 427510.0 507450.0 420380.0 450390.0 389500.0 460920.0 379860.0 433590.0 True False 304424.19935914286 363140.7468810754 421840.93806992867 390465.24252434674 362017.49328699504 422227.0421010073 424164.7454385187 389695.4048879147 399938.6241004399 418410.1460745244 0.7275736552165751 0.8679061688346229 1.0081995908263497 0.9332116971532515 0.8652215934135472 1.0091223792307442 1.0137534890537032 0.9313717856605341 0.9558530734797371 1.0 18.674558310519572 -4.888367285776171 2.8308804889153865 0.9606075454625962 0.7112014274965918 0.72625029462524 0.0450034866788744 0.18199813979201365 2.3804158690176718 0.012138015349835966 0.09463193157031208 1.293101793973939e-05 4.888367285776171 -0.24940611796600443 SRGS(ph)TNLFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SRGSTNLFSK 10 1 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;A2SY06 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 S(0.318)RGS(0.516)T(0.166)NLFSK;S(0.009)RGS(0.849)T(0.142)NLFSK;S(0.002)RGS(0.798)T(0.2)NLFSK 101.43 0.0017008 55770000.0 135814.0 125897.0 163359.0 191423.0 194171.0 172269.0 176639.0 185512.0 173448.0 135915.0 True False 158804.6277512271 138395.22213571292 167254.0981024573 180698.18991173932 156124.58641818597 163234.9103777577 159906.47516438595 180642.50656621138 175984.3488686219 160555.31359745192 0.9890960578818699 0.8619784610972184 1.0417225961253498 1.1254575501922663 0.9724037337663282 1.016689555270803 0.995958785676239 1.125110732984662 1.0960979423568253 1.0 17.29271088645683 -5.326142326661668 9.071855738005855 1.0485823245164803 0.9257202965604896 0.4075931602185815 0.05839045695209368 0.36961245297033324 49.66663409698319 0.015565911604274105 0.0325182496619745 4.7190836246498845e-06 5.326142326661668 -0.12286202795599066 SRGS(ph)TNLFSK ddPTM_PC-9_Lapatinib_30min_R1 2 SRGSTNLFSK 10 1 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;A2SY06 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 S(0.012)RGS(0.868)T(0.121)NLFSK;S(0.008)RGS(0.763)T(0.229)NLFSK 81.789 0.007456399999999999 54964000.0 415430.0 267145.0 339398.0 273751.0 249858.0 274798.0 240189.0 225041.0 288488.0 175475.0 True False 409505.89201946923 266526.4421658393 311494.00655416737 293883.5617465662 235161.84367972828 263045.5301254253 252624.81116619697 235497.22641256065 255995.4435266833 205805.61994426028 1.989770211962037 1.2950396701412938 1.513534988201641 1.4279666504061486 1.1426405350029738 1.278126079339659 1.2274922873078833 1.1442701442086078 1.2438700342391829 1.0 17.650922852951552 -1.5228787452803376 0.49424149475233065 1.1741471700854598 22.377567328040822 0.7386582175496784 0.13318905360344058 55.1014104065625 0.5948058629037504 0.07196391369176589 1209.4720200595966 0.029999999999999995 1.5228787452803376 21.203420157955364 SRGVYWHS(ph)ELQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRGVYWHSELQK 12 1 Q9NX65-3;Q9NX65-2;Q9NX65 Q9NX65-3 ZSCAN32 Zinc finger and SCAN domain-containing protein 32 1 SRGVY(0.102)WHS(0.898)ELQK 52.823 0.044199 14507000.0 10589.0 9241.8 16207.0 34955.0 34922.0 30986.0 23837.0 37619.0 31875.0 27282.0 True False 12381.508557716776 10159.264827071587 16593.43634538978 32996.584675639024 28079.28478967458 29361.03961226451 21578.986795064844 36631.541110625265 32341.111573424518 32228.010635806844 0.38418469875892164 0.3152309009040776 0.5148762215857557 1.0238480137206563 0.8712695644476786 0.9110410178294718 0.6695724113696788 1.1366367451153156 1.0035093986686232 1.0 14.976027516304494 -5.636631945728898 4.1267168737255595 0.934421202359423 0.3619800196945129 0.8185126591664689 0.11787441700745387 0.08890740836373581 2.721062342043741 0.033902276065387905 0.061297726982166324 2.3087029308474474e-06 5.636631945728898 -0.5724411826649102 down SRIPS(ph)PLQPEMQGTPDDEPSEPEPSPSTLIYR ddPTM_PC-9_AZD4547_30min_R2 1 SRIPSPLQPEMQGTPDDEPSEPEPSPSTLIYR 32 1 Q96GY3;K7EMY4 Q96GY3 LIN37 Protein lin-37 homolog 1 S(0.067)RIPS(0.665)PLQPEMQGT(0.265)PDDEPS(0.002)EPEPSPSTLIYR 79.407 5.8954e-07 17382000.0 24318.0 19385.0 36176.0 50359.0 42057.0 37381.0 28739.0 40940.0 28188.0 36342.0 True False 32050.618154177602 25650.822155663966 35696.28260302153 38749.51058879411 36218.111506663314 35043.56016070021 31296.715325179917 34613.66370760918 29677.960133057462 35069.67764164387 0.9139125395358281 0.7314245205722854 1.0178674286025826 1.1049291922427191 1.0327472033462812 0.9992552688618771 0.8924152552807126 0.9869969168609296 0.846256998319712 1.0 15.09793654903555 -5.27496035335467 24.980830368701344 0.9877767412621542 0.8226685260193921 0.4018835860216412 0.07918766387503752 673.149775176376 1243685.8151017854 0.021539058378299697 0.04524164704895975 5.309329107644163e-06 5.27496035335467 -0.1651082152427621 SRIPS(ph)PLQPEMQGTPDDEPSEPEPSPSTLIYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SRIPSPLQPEMQGTPDDEPSEPEPSPSTLIYR 32 1 Q96GY3;K7EMY4 Q96GY3 LIN37 Protein lin-37 homolog 1 S(0.11)RIPS(0.729)PLQPEMQGT(0.161)PDDEPSEPEPSPSTLIYR;S(0.045)RIPS(0.937)PLQPEMQGT(0.018)PDDEPSEPEPSPSTLIYR;S(0.151)RIPS(0.791)PLQPEMQGT(0.05)PDDEPS(0.008)EPEPSPSTLIYR 127.25 5.8064e-16 28828700.0 39257.7 27135.9 39160.9 47878.0 55955.0 54062.0 55785.0 47541.0 47038.2 36190.7 True False 45903.25323508149 29829.772817084562 40094.6443745403 45195.55088257031 44991.01942632842 51226.89354928821 50500.64095157497 46293.09912385321 47726.04468746843 42751.78742457643 1.0737154163686122 0.6977432901422157 0.9378472056934715 1.0571616675046678 1.0523775059862115 1.198239807859817 1.181252153273573 1.0828342371772042 1.116352030231898 1.0 15.383697118955343 -5.805115997769555 2.4323316077743464 1.1153661351922135 0.8729051625090762 0.4465925640474525 0.10074883690804184 0.22658523193771718 2.733049560997856 0.029088095482907916 0.05167507211329271 1.5663326550269917e-06 5.805115997769555 -0.24246097268313727 SRIPS(ph)PLQPEMQGTPDDEPSEPEPSPSTLIYR ddPTM_PC-9_Lapatinib_30min_R1 1 SRIPSPLQPEMQGTPDDEPSEPEPSPSTLIYR 32 1 Q96GY3;K7EMY4 Q96GY3 LIN37 Protein lin-37 homolog 1 S(0.047)RIPS(0.798)PLQPEMQGT(0.152)PDDEPS(0.002)EPEPSPSTLIYR 78.311 2.2645e-07 3040700.0 4199.2 2421.2 3837.9 2166.9 3640.4 3610.1 2884.9 1182.4 3564.9 2767.7 True False 4139.3186379610315 2415.5938601580833 3522.3626767224223 2326.2610545664957 3426.2788293017743 3455.70443855413 3034.2660060758885 1237.3386205634195 3163.383421938774 3246.0932572715647 1.27516935278694 0.7441541781792369 1.0851082817266533 0.7166340798605969 1.0555084397611116 1.0645733701005096 0.9347439415915848 0.3811777797177147 0.9745201912645262 1.0 11.664488732444017 -7.549985007468468 24.999256900025166 0.7383015017135741 0.9760070573382372 0.1351888340259586 0.22100191014664033 347.42374880246433 320413.9105862698 0.09680269935440872 0.055890588022921524 2.8184802279746005e-08 7.549985007468468 0.2377055556246631 SRIPSPLQPEMQGT(ph)PDDEPSEPEPSPSTLIYR ddPTM_PC-9_AZD4547_30min_R2 1 SRIPSPLQPEMQGTPDDEPSEPEPSPSTLIYR 32 1 Q96GY3;K7EMY4 Q96GY3 LIN37 Protein lin-37 homolog 1 S(0.008)RIPS(0.068)PLQPEMQGT(0.924)PDDEPSEPEPSPSTLIYR 105.5 1.0269e-15 17893000.0 26699.0 25690.0 41177.0 59320.0 48060.0 43762.0 34483.0 45075.0 32521.0 38588.0 True False 35188.726626300995 33993.79010466892 40630.96607542617 45644.690484863975 41387.698575985916 41025.55522197276 37551.92019757748 38109.694470456365 34239.99366706262 37237.04586527309 0.9449924345131165 0.9129024420374658 1.0911436482483756 1.2257871005667444 1.111465681937559 1.1017403305946136 1.008455942865168 1.0234349579808397 0.9195142329750307 1.0 15.184451003343796 -10.178604240306196 9.459297358526493 0.9999999236056387 1.0439188358643385 0.0105814305818277 0.09344388148328635 0.0 0.0 0.10037398407898082 0.024344266965982554 6.628202370213754e-11 10.178604240306196 0.043918912258699816 SRIPSPLQPEMQGT(ph)PDDEPSEPEPSPSTLIYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRIPSPLQPEMQGTPDDEPSEPEPSPSTLIYR 32 1 Q96GY3;K7EMY4 Q96GY3 LIN37 Protein lin-37 homolog 1 S(0.007)RIPS(0.051)PLQPEMQGT(0.943)PDDEPSEPEPSPSTLIYR 110.07 4.627500000000001e-16 5659300.0 10471.0 6754.5 12770.0 15246.0 17914.0 19461.0 19770.0 14928.0 16610.0 13073.0 True False 12243.53348832301 7425.042121064629 13074.485230494696 14391.8160481989 14403.880296725001 18440.43090086748 17897.242477595013 14536.155817523428 16852.889826967246 15443.03141418894 0.7928193085894875 0.4808021120932615 0.8466268622934976 0.9319294678747988 0.9327106777423781 1.1940939836413562 1.1589202921099522 0.9412760634656042 1.0912941491191257 1.0 13.914668356050964 -5.763790265608434 1.4540762517563517 1.06605967636561 0.6331130947236315 0.680883336333731 0.11015715437863478 0.2324029683918707 0.988757024975366 0.03636132125580547 0.08453643419389946 1.7227003200086373e-06 5.763790265608434 -0.4329465816419785 SRIPSPLQPEMQGT(ph)PDDEPSEPEPSPSTLIYR ddPTM_PC-9_Lapatinib_30min_R1 2 SRIPSPLQPEMQGTPDDEPSEPEPSPSTLIYR 32 1 Q96GY3;K7EMY4 Q96GY3 LIN37 Protein lin-37 homolog 1 S(0.002)RIPS(0.027)PLQPEMQGT(0.971)PDDEPSEPEPSPSTLIYR;S(0.048)RIPS(0.386)PLQPEMQGT(0.566)PDDEPSEPEPSPSTLIYR 111.95 2.3083e-16 22369000.0 59561.0 42556.0 51142.0 38425.0 38778.0 43992.0 29408.4 32612.0 39983.0 33668.0 True False 58711.64921785029 42457.46419663285 46937.30217382898 41250.9026820424 36497.154280481314 42110.564710360755 30931.023055593687 34127.272575959236 35479.69350034448 39487.46894020992 1.4868425552103308 1.075213614246078 1.1886632249055835 1.044658059611331 0.9242718072344318 1.0664285617830458 0.7833123744251119 0.8642557624453763 0.8985051321994372 1.0 15.269107276736596 -1.5228787453341786 0.43441860083136474 0.8914359412808847 12.033948819418294 0.7534644554193225 0.09355972791571124 39.5075763941073 0.4921103661281991 0.060065930765306495 386.4692866028071 0.029999999996280797 1.5228787453341786 11.14251287813741 SRKNMINMKIDSWSVWK ddPTM_PC-9_AZD4547_30min_R2 1 SRKNMINMKIDSWSVWK 17 3 A0A0A0MS97;F8W7A7;Q5BJE1-3;Q5BJE1-2;Q5BJE1-4;Q5BJE1 A0A0A0MS97 CCDC178 Coiled-coil domain-containing protein 178 0 54.598 0.038321 0.0 13962.0 9196.7 12997.0 16763.0 16826.0 11771.0 9178.9 15808.0 12007.0 15452.0 False True 18401.62557235906 12169.35342372942 12824.651287911063 12898.549335768286 14490.000337901356 11034.957509205271 9995.804318114544 13365.236831702154 12641.665507223666 14911.030183222754 1.234094851009273 0.8161309630653052 0.8600781522353034 0.8650340839817476 0.9717638660677435 0.7400533278794732 0.670363093313391 0.8963322230237412 0.8478063119641137 1.0 13.864092314493696 -4.758957237497802 24.99223467390042 0.8439471951107917 1.2340953652292455 0.6038294802796015 0.09265671439227594 45.999606229249444 463064.3905984075 0.023465364465690183 0.15453779943489257 1.7419783876301868e-05 4.758957237497802 0.3901481701184537 SRLDQELK ddPTM_PC-9_AZD4547_30min_R2 2 SRLDQELK 8 1 P46781;B5MCT8;C9JM19;F2Z3C0;A8MXK4 P46781 RPS9 40S ribosomal protein S9 0 ; 97.965 0.007325399999999999 16201600.0 41544.0 48598.0 65822.0 82654.0 59337.0 61687.0 45037.0 67720.0 53833.0 58739.0 False True 54754.127831119054 64306.35311431298 64949.15727266921 63599.397291570305 51099.0817811751 57829.70213833536 49045.205751770314 57255.43005078888 56678.50247775229 56682.56548876014 0.965978292601744 1.1344996924506636 1.1458401134921865 1.1220275007520917 0.901495571708161 1.0202379098349508 0.8652608668797062 1.0101065390581576 0.999928319916842 1.0 15.790617436573037 -6.250759319503243 24.761988573190646 0.9643346463080688 1.098955479123503 0.46694065724974587 0.06572697197243595 539.1770869583459 1250095.1966675238 0.019234497741195525 0.024580430037389547 5.613589878803995e-07 6.250759319503243 0.13462083281543424 SRLDTDYRY(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRLDTDYRYK 10 2 Q9BYV8-5 Q9BYV8-5 CEP41 Centrosomal protein of 41 kDa 1 SRLDTDY(0.011)RY(0.989)K 69.979 0.034789999999999995 0.0 22187.0 27052.0 21475.0 24883.0 26945.0 22939.0 26062.0 21008.0 20575.0 19361.0 True False 25942.820886775164 29737.543779560343 21987.045444391028 23488.88618177446 21665.32067630093 21736.03845819841 23593.218687459834 20456.562259815913 20875.870450924194 22870.996038408324 1.134310934390797 1.3002295015757384 0.9613505860202661 1.0270163198108417 0.947283653056358 0.9503756820077304 1.0315781021446835 0.8944325041840006 0.9127661259643601 1.0 14.481231576448197 -5.2727372976583 24.974966147881617 0.9651819604279585 1.2172702154216535 0.762779507781074 0.05613901006349692 276.2790862169609 610737.7418791815 0.014341353703023724 0.030287045876220293 5.336576044229586e-06 5.2727372976583 0.252088254993695 SRLRDGPS(ph)APLEAPEPR ddPTM_PC-9_AZD4547_30min_R2 1 SRLRDGPSAPLEAPEPR 17 2 Q13164-2;Q13164 Q13164-2 MAPK7 Mitogen-activated protein kinase 7 1 SRLRDGPS(1)APLEAPEPR 106.82 0.008709999999999999 0.0 18425.0 14566.0 17765.0 30411.0 28689.0 19742.0 17279.0 23877.0 22039.0 25532.0 True False 24283.766736192196 19274.174646345185 17529.4244925552 23400.213795266332 24706.027558186852 18507.52961912586 18816.797526141618 20187.358288876032 23203.936546489764 24638.13245133597 0.9856171844256582 0.7822904063209576 0.711475373678523 0.9497559866392182 1.0027556920957783 0.7511742075289605 0.7637266161835777 0.819354239967218 0.941789585404699 1.0 14.58860528471755 -8.444434726220662 3.7420172451802816 0.9985349317150085 0.84232544554622 0.2201188781908482 0.0968209030992781 0.33121159214591883 8.680531954590174 0.09772012579675231 0.025760258678808903 3.593894083606493e-09 8.444434726220662 -0.1562094861687885 SRLS(ph)AIEIDIPVVSHTT ddPTM_PC-9_AZD4547_30min_R2 4 SRLSAIEIDIPVVSHTT 17 1 P56749 P56749 CLDN12 Claudin-12 1 S(0.007)RLS(0.993)AIEIDIPVVSHTT;S(0.035)RLS(0.965)AIEIDIPVVSHTT;S(0.101)RLS(0.899)AIEIDIPVVSHTT;S(0.102)RLS(0.898)AIEIDIPVVSHTT 172.09 4.6427e-06 62998600.0 99057.0 151610.0 186598.0 227549.0 202787.0 151302.0 165022.0 257414.0 162337.0 151700.0 True False 130555.0654864037 200614.96760486 184123.5885990328 175091.09364700475 174633.52540841574 141841.06202172962 179708.6383100262 217636.58108525968 170917.80240244593 146389.02917388655 0.8918364048396369 1.3704235128614848 1.2577690393746903 1.1960670457007045 1.1929413453584645 0.9689323224710051 1.2276100150685563 1.4867000779596846 1.1675588216342576 1.0 17.159447912283525 -7.5138671829006975 24.948234994544865 1.2677086571820626 1.1603188451894704 0.01571079157859201 0.17156615400499944 1218.0197347553217 3372079.375937322 0.0751083580332027 0.046282952581506706 3.0628999947359406e-08 7.5138671829006975 -0.10738981199259223 SRLS(ph)AIEIDIPVVSHTT ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SRLSAIEIDIPVVSHTT 17 1 P56749 P56749 CLDN12 Claudin-12 1 S(0.411)RLS(0.589)AIEIDIPVVSHTT;S(0.124)RLS(0.876)AIEIDIPVVSHTT;S(0.454)RLS(0.536)AIEIDIPVVS(0.003)HT(0.003)T(0.003);S(0.09)RLS(0.91)AIEIDIPVVSHTT;S(0.345)RLS(0.655)AIEIDIPVVSHTT 172.99 3.593e-06 52792300.0 82376.3 76763.9 97072.2 81717.7 159967.0 77715.8 74637.8 79369.9 76288.7 64908.3 True False 96320.98058391227 84384.51267705874 99386.76939636834 77139.32220135792 128622.61468271771 73640.24663715315 67567.56725312278 77286.52422436026 77404.27791345902 76675.66097617989 1.25621324104184 1.1005384446998596 1.2961970999799257 1.0060470456892712 1.6774894803016527 0.9604122833715157 0.8812127133030305 1.0079668468507905 1.0095025843664456 1.0 16.226481077728366 -6.901101226782232 23.32506000714061 0.9664877113264804 1.2525154603321598 0.43805544989305356 0.16685023601977886 7.81704128654836 1831.6128953968562 0.056591148974585545 0.04990869882018882 1.2557372382274678e-07 6.901101226782232 0.2860277490056794 SRLS(ph)AIEIDIPVVSHTT ddPTM_PC-9_Lapatinib_30min_R1 3 SRLSAIEIDIPVVSHTT 17 1 P56749 P56749 CLDN12 Claudin-12 1 S(0.196)RLS(0.804)AIEIDIPVVSHTT;S(0.099)RLS(0.901)AIEIDIPVVSHTT;S(0.2)RLS(0.8)AIEIDIPVVSHTT 144.82 4.999e-05 28647510.0 162126.1 162920.7 98491.3 59001.6 95723.9 66411.2 56115.7 51910.6 107375.6 37753.0 True False 159814.1520837146 162543.46712896807 90393.72550141267 63340.77448756777 90093.60840242836 63570.94778806855 59021.096369771156 54322.5559849623 95281.8292128051 44278.55574728957 3.609290081542403 3.67092973981921 2.041478633976131 1.4305067863792071 2.0347007006420545 1.4357050882798934 1.3329498980640087 1.2268366722482262 2.1518730140297677 1.0 15.434320545431248 -5.346449576225915 3.073249554196945 1.541065064819493 3.6931306510087105 0.8630989505818096 0.33285462874142274 0.08169354288831028 1.4758583848111728 0.08838454153715612 0.22630159857546678 4.503502661841701e-06 5.346449576225915 2.1520655861892175 SRLS(ph)SSSSNDSGNK ddPTM_PC-9_AZD4547_30min_R2 2 SRLSSSSSNDSGNK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(0.04)RLS(0.952)S(0.006)S(0.001)SSNDSGNK;S(0.009)RLS(0.983)S(0.006)S(0.001)SSNDSGNK 159.44 0.00013741 36644000.0 14723.8 13240.900000000001 23613.0 32211.0 26061.0 27986.0 22972.0 29115.0 20617.4 22401.1 True False 19405.662125934705 17520.761985088007 23299.876191539894 24785.2516049891 22442.879995604842 26236.03099588978 25016.463497339268 24615.9457461417 21707.193672743673 21616.84430736419 0.8977102231024441 0.8105143255863311 1.0778574273027606 1.146571222541744 1.0382125936836788 1.2136845981238795 1.157267135833371 1.1387390960555612 1.004179581630641 1.0 14.399868308986086 -5.321019786036573 5.437445889913845 1.1096108970446446 0.8542610638833663 0.6613617480251472 0.06923120329136843 0.10384164551203062 6.4532964632573995 0.017866851936318623 0.03892199842847338 4.775075183813976e-06 5.321019786036573 -0.25534983316127824 SRLS(ph)SSSSNDSGNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SRLSSSSSNDSGNK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(0.024)RLS(0.928)S(0.035)S(0.01)S(0.002)S(0.001)NDSGNK;S(0.003)RLS(0.994)S(0.004)SSSNDSGNK;S(0.019)RLS(0.898)S(0.056)S(0.019)S(0.006)S(0.002)NDSGNK 142.94 7.2385e-05 20155500.0 45506.6 51599.6 59854.7 62542.5 69548.0 46392.3 45255.4 49420.2 41533.8 43040.0 True False 53209.96858368064 56722.067278123686 61281.86304821379 59038.446490520786 55920.5686544954 43959.406119023406 40968.48089127732 48122.97211503022 42141.15325077014 50842.81129554748 1.046558347735198 1.1156359342208735 1.2053201128471136 1.1611955552050883 1.0998716874531405 0.8646139935789333 0.8057870886235811 0.9465049411861408 0.828851752626445 1.0 15.633756184282785 -6.716699605038711 5.134936374866352 0.8800598303889313 1.1346214254783042 0.7712442137154101 0.06440037723154494 0.0872019815115889 5.175694189962189 0.02174139149142841 0.02121667346362685 1.9199963140595373e-07 6.716699605038711 0.2545615950893729 SRLSSSSSNDS(ph)GNK ddPTM_PC-9_AZD4547_30min_R2 1 SRLSSSSSNDSGNK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 SRLS(0.092)S(0.003)S(0.001)S(0.001)S(0.002)NDS(0.901)GNK 100.4 0.014737 0.0 3486.6 4424.0 3116.6 5553.2 5932.8 6106.7 5387.6 8496.4 4608.4 4208.2 True False 4595.266274214802 5853.9714839647895 3075.2718476497334 4272.995536084741 5109.133127582383 5724.847083634684 5867.085962835845 7183.476607848822 4851.990615764933 4060.872198876391 1.1315958860971478 1.4415552121006256 0.7572934328001347 1.0522359056921424 1.2581368921179144 1.4097580035192196 1.444784685531157 1.7689491951597072 1.1948149013671097 1.0 11.98757390908056 -6.5457521827873455 3.123399308741318 1.4165435550611862 1.0984080003364158 0.19816851437711258 0.24206988650042402 0.35266997313150955 7.1021611906884425 0.08305509268099208 0.08708613930115325 2.846084677646759e-07 6.5457521827873455 -0.3181355547247704 SRLT(ph)PVS(ph)PESSSTEEK ddPTM_PC-9_AZD4547_30min_R2 1 SRLTPVSPESSSTEEK 16 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 2 S(0.237)RLT(0.763)PVS(0.998)PES(0.002)SSTEEK 81.574 0.025925 13904000.0 29998.0 27156.0 28583.0 42623.0 38562.0 41224.0 33773.0 43895.0 31426.0 30104.0 True False 39536.74000283819 35933.64593547643 28203.97074419959 32796.92586878554 33208.33192857197 38646.25676318735 36778.73157302973 37112.036356753924 33087.114202549456 29050.068122944478 1.3609861372962175 1.236955651305173 0.9708745130935985 1.1289793101339305 1.143141275539495 1.3303327413770698 1.2660463107135007 1.277519770338917 1.1389685580949263 1.0 14.826253926329647 -8.540687598755397 17.260883889717412 0.9999999916462665 1.2074166000650381 0.27292984565004796 0.10684208841117739 63.32298250177838 61377.05867224695 0.11224492838312758 0.028982393434265483 2.8794689596425923e-09 8.540687598755397 0.20741660841877163 SRLT(ph)PVS(ph)PESSSTEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SRLTPVSPESSSTEEK 16 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 2 SRLT(1)PVS(0.469)PES(0.424)S(0.082)S(0.015)T(0.011)EEK;SRLT(1)PVS(0.931)PES(0.064)S(0.004)STEEK;S(0.045)RLT(0.96)PVS(0.995)PES(0.001)SSTEEK 242.1 9.833000000000001e-36 49109700.0 260904.0 259342.0 270566.0 308061.0 321106.0 303359.0 319750.0 320628.0 275012.0 252137.0 True False 305069.89411110914 285087.75982843136 277017.31956726906 290801.3409172381 258187.58437870847 287450.3200070014 289460.9652104702 312211.85473344685 279033.53022841224 297847.44218460587 1.0242488297818815 0.9571603426821907 0.9300644569429396 0.9763432540642716 0.8668450616362312 0.9650924577315647 0.971843045175665 1.0482274161680996 0.9368337299853905 1.0 18.184214044183292 -7.372591465978791 3.44693112080425 0.9961152481158678 0.9494129780000059 0.13858955595306688 0.04496973468910403 0.4470119248733159 9.851889551750888 0.0203596451949473 0.013054659324675706 4.2404166785338535e-08 7.372591465978791 -0.04670227011586192 SRLT(ph)PVS(ph)PESSSTEEK ddPTM_PC-9_Lapatinib_30min_R1 2 SRLTPVSPESSSTEEK 16 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 2 SRLT(1)PVS(0.699)PES(0.247)S(0.049)S(0.004)T(0.001)EEK;S(0.351)RLT(0.649)PVS(0.961)PES(0.028)S(0.007)S(0.002)T(0.002)EEK 193.41 6.9785e-38 0.0 102722.0 109775.0 76800.0 88447.0 97700.0 82201.0 79030.0 72848.0 88331.0 69995.0 True False 101257.16544309235 109520.8227320561 70485.8004565731 94951.68743054265 91953.47808559053 78685.45484989007 83121.78670324011 76232.78402469904 78382.23261333394 82093.54248752524 1.2334364235588833 1.3340979011680323 0.8586034701485074 1.1566279704030473 1.1201061045643583 0.9584853140165921 1.0125252752476983 0.9286087762174865 0.9547916954033837 1.0 16.324981123018752 -1.522878769423584 0.37306938744545404 0.9620689529539125 5.557415088792217 0.44593812217984696 0.10606164402476319 58.89109962384841 0.8107750226477222 0.08234447478981095 194.46360093188946 0.029999998332243673 1.522878769423584 4.595346135838304 SRLT(ph)PVSPES(ph)SSTEEK ddPTM_PC-9_AZD4547_30min_R2 4 SRLTPVSPESSSTEEK 16 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 2 S(0.103)RLT(0.897)PVS(0.448)PES(0.49)S(0.058)S(0.002)T(0.002)EEK;S(0.056)RLT(0.944)PVS(0.211)PES(0.524)S(0.211)S(0.042)T(0.011)EEK;S(0.004)RLT(0.994)PVS(0.262)PES(0.65)S(0.071)S(0.015)T(0.003)EEK;S(0.103)RLT(0.897)PVS(0.018)PES(0.762)S(0.171)S(0.039)T(0.009)EEK 140.3 0.0019089999999999999 279298500.0 551969.0 556871.0 634792.0 778720.0 741855.0 697226.0 616281.0 687072.0 602536.0 657999.0 True False 727483.6603315744 736868.6605440675 626374.2433142749 599198.1351040668 638861.2385994185 653628.3480004369 671128.8151055072 580900.8097438805 634384.8228583757 634962.6552893067 1.1457109394884217 1.1604913366256628 0.986474146308465 0.9436746084398546 1.0061398623645599 1.0293965204971396 1.0569579321160583 0.9148582281255674 0.999089974148688 1.0 19.27631221811177 -5.261956837101403 24.998310944016023 0.991457174127315 1.15310115165679 0.742841854804993 0.03789617137861936 21.835196410375982 1054918.0295683676 0.010314470313286968 0.023808459704575017 5.4707033145920616e-06 5.261956837101403 0.1616439775294749 SRLT(ph)PVSPES(ph)SSTEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRLTPVSPESSSTEEK 16 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 2 S(0.311)RLT(0.69)PVS(0.315)PES(0.355)S(0.255)S(0.06)T(0.015)EEK 121.51 0.016422 8167000.0 28365.0 31907.0 39097.0 38872.0 41834.0 41253.0 43226.0 37873.0 35857.0 29582.0 True False 33166.63426571313 35074.51609398311 40029.22075619821 36694.127864724374 33636.92800788175 39089.62005824398 39131.320350860966 36878.87387976049 36381.340790220616 34944.98242901684 0.9491100570184564 1.0037067886707167 1.1454926565640402 1.0500542657092629 0.9625681763099432 1.1186046562663488 1.1197979690030684 1.0553410337141227 1.0411034220469684 1.0 15.092797700831342 -6.780553890751284 24.999981000137808 1.0737299916125282 1.0295582707670428 0.11014782647234322 0.06038503309956573 605.8661556022626 792409.5095888802 0.02243915024579194 0.019820013984953925 1.6574716516780757e-07 6.780553890751284 -0.044171720845485485 SRLT(ph)PVSPES(ph)SSTEEK ddPTM_PC-9_Lapatinib_30min_R1 1 SRLTPVSPESSSTEEK 16 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 2 S(0.003)RLT(0.996)PVS(0.008)PES(0.79)S(0.162)S(0.034)T(0.007)EEK 149.24 0.0065706 133760000.0 475720.0 420910.0 442300.0 402880.0 463380.0 413110.0 389020.0 380060.0 469940.0 374750.0 True False 468936.145563636 419935.4087556332 405935.8013273747 432509.1391682817 436124.89944013214 395442.2483064446 409161.5521105215 397718.975077244 417010.4085124147 439525.0381770124 1.0669156585677348 0.9554300034814177 0.9235783313074644 0.9840375441685186 0.9922640613354298 0.899703575356237 0.9309175054226092 0.9048835459450398 0.9487750919538508 1.0 18.745585827347938 -6.748006835850164 24.98224068190411 0.9305400097401351 0.9794290426373156 0.2257600255358302 0.04278041034967554 348.4330359805956 648024.6424304326 0.014071308529472647 0.013995007718297134 1.7864594555326001e-07 6.748006835850164 0.048889032897180495 SRLT(ph)PVSPESS(ph)STEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRLTPVSPESSSTEEK 16 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 2 S(0.032)RLT(0.968)PVS(0.255)PES(0.176)S(0.547)S(0.017)T(0.004)EEK 147.49 0.0067013 43407000.0 173760.0 176220.0 157660.0 209180.0 227840.0 210220.0 225300.0 208530.0 208360.0 164890.0 True False 203174.1360835645 193713.95700259248 161419.2123288796 197460.32277071005 183196.3875631251 199195.69312884024 203957.9529692545 203056.30845579825 211406.8708216071 194783.251731478 1.0430780587011346 0.9945103353631265 0.8287119703259036 1.0137438461234982 0.9405140633737537 1.0226530841750454 1.0471021053207616 1.0424731420734532 1.0853441912605808 1.0 17.571510108311315 -6.90475444641464 4.30952201306589 1.045987122315966 0.9611971226701521 0.30864641585133623 0.05684492901563456 0.2680192292976192 9.028582196727033 0.021037558001193696 0.01839404935099998 1.2452184692849283e-07 6.90475444641464 -0.08478999964581391 SRLT(ph)PVSPESSST(ph)EEK ddPTM_PC-9_AZD4547_30min_R2 1 SRLTPVSPESSSTEEK 16 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 2 SRLT(0.996)PVS(0.071)PES(0.224)S(0.168)S(0.126)T(0.415)EEK 126.07 0.00051555 0.0 21949.0 19161.0 19967.0 34385.0 32699.0 32414.0 25548.0 25005.0 26793.0 25708.0 True False 28928.325432438676 25354.41853622272 19702.224533793957 26458.06949295429 28159.308275825304 30387.147455898375 27821.72250696603 21141.051807737367 28209.2232810064 24807.9707449062 1.1660899526970985 1.0220271055998695 0.7941892844193795 1.0665148618972353 1.1350911594253323 1.224894521537508 1.121483203646499 0.8521878724029953 1.1371032145706064 1.0 14.598516109298384 -4.756529672498839 24.09978088148882 1.0392135769178767 1.1660902561936277 0.08410453386954753 0.12554463756620238 287.22482885085736 1409604.9861899142 0.033305598942640596 0.26335152511140053 1.7517427450058403e-05 4.756529672498839 0.12687667927575097 SRLT(ph)PVSPESSSTEEK ddPTM_PC-9_AZD4547_30min_R2 10 SRLTPVSPESSSTEEK 16 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 S(0.001)RLT(0.994)PVS(0.006)PESSSTEEK;SRLT(0.869)PVS(0.13)PES(0.001)SSTEEK;S(0.007)RLT(0.993)PVSPESSSTEEK;S(0.027)RLT(0.972)PVS(0.001)PESSSTEEK;S(0.154)RLT(0.843)PVS(0.003)PESSSTEEK;S(0.238)RLT(0.759)PVS(0.003)PESSSTEEK;S(0.037)RLT(0.963)PVSPESSSTEEK;S(0.189)RLT(0.811)PVSPESSSTEEK;S(0.366)RLT(0.634)PVSPESSSTEEK;S(0.348)RLT(0.652)PVSPESSSTEEK 204.9 6.8132e-16 2555478400.0 251134.0 245593.0 335439.0 462216.0 385888.0 337713.0 338234.0 362774.0 285717.0 351481.0 True False 330989.3880882978 324976.13441712596 330990.85968805075 355659.24236601335 332314.11211173655 316595.75272332394 368336.17075391905 306715.61401720095 300819.4173171839 339175.7571724898 0.9758639321617885 0.9581349124898024 0.9758682709145496 1.0485986537803786 0.9797696476954758 0.9334268326327266 1.0859743450549728 0.904296983292998 0.886913085489776 1.0 18.371673530372924 SRLT(ph)PVSPESSSTEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 12 SRLTPVSPESSSTEEK 16 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 S(0.015)RLT(0.985)PVSPESSSTEEK;S(0.173)RLT(0.816)PVS(0.011)PESSSTEEK;S(0.173)RLT(0.826)PVS(0.001)PESSSTEEK;S(0.001)RLT(0.999)PVSPESSSTEEK;SRLT(0.961)PVS(0.032)PES(0.005)S(0.001)STEEK;S(0.339)RLT(0.659)PVS(0.002)PESSSTEEK;S(0.143)RLT(0.857)PVSPESSSTEEK;S(0.17)RLT(0.83)PVSPESSSTEEK;S(0.024)RLT(0.975)PVSPESSSTEEK;S(0.134)RLT(0.846)PVS(0.019)PESSSTEEK;S(0.23)RLT(0.77)PVSPESSSTEEK;S(0.083)RLT(0.915)PVS(0.001)PESSSTEEK 161.31 2.1335e-05 4397383800.0 446389.6 441477.10000000003 520670.0 684669.0 667967.0 568007.0 618277.0 611215.0 566507.0 456242.0 True False 521954.54268351675 485304.0288674901 533084.7474519713 646309.2156568464 537083.6613912318 538219.7130008242 559709.3266221547 595171.2538858228 574791.0931490514 538955.062990315 0.9684565161843488 0.9004536040070765 0.9891079684718552 1.1991894316214273 0.9965277223880225 0.9986356005537627 1.0385083378133375 1.1043058962719459 1.0664916847796277 1.0 19.039805463363265 -5.528022784996012 24.99993976802544 1.0591250403910955 0.9370364664593452 0.4140560329649773 0.059613212971507054 121.98022350670654 592820.2659499514 0.01628129975255831 0.02831915080366116 2.9646758455279257e-06 5.528022784996012 -0.12208857393175021 SRLT(ph)PVSPESSSTEEK ddPTM_PC-9_Lapatinib_30min_R1 11 SRLTPVSPESSSTEEK 16 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 S(0.227)RLT(0.763)PVS(0.007)PES(0.002)S(0.001)STEEK;S(0.057)RLT(0.942)PVS(0.001)PESSSTEEK;S(0.047)RLT(0.953)PVSPESSSTEEK;S(0.046)RLT(0.954)PVSPESSSTEEK;S(0.036)RLT(0.964)PVSPESSSTEEK;S(0.009)RLT(0.991)PVSPESSSTEEK;S(0.045)RLT(0.955)PVSPESSSTEEK;S(0.001)RLT(0.999)PVSPESSSTEEK;S(0.008)RLT(0.991)PVS(0.001)PESSSTEEK;S(0.007)RLT(0.992)PVSPESSSTEEK;S(0.209)RLT(0.791)PVSPESSSTEEK 166.57 1.4766e-20 4684520000.0 598208.0 517651.0 526330.0 515810.0 489555.0 471972.0 400480.0 409899.0 487740.0 340372.1 True False 589677.4442220875 516452.41091388365 483057.1790925539 553744.388091719 460760.33740216173 451786.85778046877 421214.8948363108 428944.4039498693 432805.5850701047 399204.963967686 1.4771295385741232 1.2937023772973133 1.210048027187496 1.3871179921914556 1.1541949098595337 1.1317165330064358 1.055134411781529 1.0744966687954074 1.084168845919307 1.0 18.606770134608574 -3.9756679967742814 0.24498002445746553 0.9802913355749493 2.021416710200999 0.8108075694870216 0.06390540934551803 6.788538944020678 0.2537640732663632 0.09599930525463808 2.2776267801496943 0.00010576257188126375 3.9756679967742814 1.0411253746260494 SRLTPVS(ph)PESSSTEEK ddPTM_PC-9_AZD4547_30min_R2 3 SRLTPVSPESSSTEEK 16 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 SRLTPVS(0.994)PES(0.004)S(0.001)STEEK;SRLT(0.002)PVS(0.826)PES(0.13)S(0.032)S(0.002)T(0.008)EEK;SRLTPVS(1)PESSSTEEK 215.51 2.574e-21 84542000.0 96743.0 63133.2 90648.0 183311.0 143172.0 121830.0 91985.0 105722.0 61867.5 102017.0 True False 127505.26162059407 83539.7722629851 89445.94829164908 141051.481076718 123295.03912861146 114211.9508407509 100171.48680144298 89385.09414987447 65137.68974499546 98445.41588155822 1.2951873937329736 0.8485897643369559 0.9085841884122203 1.4327887166063682 1.25242031865608 1.160155095267836 1.0175332787659856 0.9079660373156997 0.6616630054502894 1.0 16.587036408033626 -7.669965966283739 2.3950318134013258 0.824267308180337 1.1407833096063031 0.3488041364754506 0.1795075041987282 0.35757447054682967 4.109814953703592 0.11717529625869622 0.05526789380160471 2.138129638594577e-08 7.669965966283739 0.31651600142596614 SRLTPVS(ph)PESSSTEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SRLTPVSPESSSTEEK 16 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 SRLT(0.006)PVS(0.991)PES(0.003)SSTEEK;SRLT(0.01)PVS(0.989)PESSSTEEK;S(0.007)RLT(0.005)PVS(0.986)PES(0.002)SSTEEK 190.25 1.1847999999999999e-07 64560600.0 53324.0 31458.6 28662.300000000003 70649.0 56638.0 80112.0 68703.0 64294.0 69013.0 61058.0 True False 62350.7000029927 34581.60190535551 29345.71793437807 66690.76557714852 45540.190479284945 75910.7856908841 62194.95447335401 62606.35062512398 70022.1845652312 72127.33206513802 0.8644531582935014 0.4794521149641989 0.40685988368287385 0.9246254321027741 0.631386038764857 1.0524551999556737 0.8622938446854779 0.8679975930425977 0.97081345670729 1.0 16.138258440162588 -6.290199594200248 1.3753515230015643 0.9305133765327056 0.5962366131144172 0.41424627311835827 0.16171760854952283 0.40731861586738427 1.5563136796055077 0.06198260973664024 0.08473946123737758 5.126257359616312e-07 6.290199594200248 -0.3342767634182884 SRLTPVS(ph)PESSSTEEK ddPTM_PC-9_Lapatinib_30min_R1 5 SRLTPVSPESSSTEEK 16 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 SRLT(0.029)PVS(0.969)PES(0.001)S(0.001)S(0.001)TEEK;SRLT(0.001)PVS(0.997)PES(0.001)SSTEEK;SRLTPVS(0.942)PES(0.046)S(0.012)STEEK;SRLTPVS(0.995)PES(0.004)S(0.001)STEEK;SRLTPVS(1)PESSSTEEK 241.98 2.5788e-37 281208100.0 365069.0 186309.0 199442.0 184113.0 167143.0 169784.0 121825.0 111226.0 154449.0 125542.0 True False 359863.04911454406 185877.61295729096 183044.64862838387 197653.2842029634 157311.97735578124 162522.73410583503 128132.50240569707 116393.96601047576 137053.32719992753 147241.76742580027 2.4440283175484856 1.2623973224918026 1.2431571002475625 1.3423723964911456 1.0683923461802758 1.1037814673593573 0.8702184485137143 0.7904955777519468 0.9308046867135916 1.0 17.167827446855867 -1.9101430128089505 0.8259242544771441 0.9847781208209724 199.9999999999991 0.8827573767452603 0.15270040363438203 96.16197424573932 0.6143486392010565 0.058261487051625385 35458.912528463545 0.012298637110337057 1.9101430128089505 199.0152218791781 up SRMTFFVTQLAIT(ph)EK ddPTM_PC-9_AZD4547_30min_R2 1 SRMTFFVTQLAITEK 15 1 Q6W5P4-2 Q6W5P4-2 1 SRMTFFVT(0.001)QLAIT(0.999)EK 58.29 0.038348 6941300.0 0.0 2138.0 63215.0 80471.0 58323.0 41793.0 11818.0 88019.0 22519.0 42918.0 True False 0.0 2829.0666891312626 62376.72779605278 61919.654214556496 50225.858178261056 39179.677103238144 12869.77910550041 74417.6860254042 23709.308366550344 41415.45388322251 0.0 0.06830944548158926 1.5061220377285718 1.4950857327110034 1.2127322887702956 0.9460158812628616 0.31074823281639774 1.7968579128756323 0.5724749131906782 1.0 15.337881579170537 -5.2461457854211275 23.43016747912576 1.1171982242735155 0.03415403647014699 0.510578763518512 0.4192352423618902 278.0197244471475 425928.2797748781 0.10637360972351369 0.27863221427659113 5.673541221140665e-06 5.2461457854211275 -1.0830441878033685 SRMTFFVTQLAIT(ph)EK ddPTM_PC-9_Lapatinib_30min_R1 1 SRMTFFVTQLAITEK 15 1 Q6W5P4-2 Q6W5P4-2 1 SRMTFFVTQLAIT(1)EK 65.265 0.02216 4223500.0 4677.7 1536.0 54118.0 5885.6 19704.0 31900.0 11517.0 12226.0 50619.0 8134.3 True False 4610.995140214877 1532.4434863715585 49668.62694152115 6318.446657786038 18545.049459554495 30535.71136253201 12113.293906886203 12794.064593207338 44917.75517829921 9540.302916726554 0.4833174774912693 0.16062838882031713 5.206189716936507 0.6622899412038803 1.9438637977668771 3.2007066891969664 1.2696969910303946 1.3410543359976674 4.70821058517409 1.0 13.219819359018787 SRNEVVT(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 1 SRNEVVTPEK 10 1 A0A494C142;Q99728-3;Q99728-2;Q99728;A0A087X2H0 A0A494C142 BARD1 BRCA1-associated RING domain protein 1 1 SRNEVVT(1)PEK 65.219 0.035595 16457000.0 73253.0 70971.0 88349.0 91321.0 80832.0 83404.0 76830.0 75018.0 82496.0 87601.0 True False 96545.93024294621 93910.98783645236 87177.4345337889 70268.35434538547 69609.87206188281 78188.73469524735 83667.72116056846 63425.69184214523 86856.57014107799 84534.11565366913 1.142094283430949 1.1109241175621885 1.0312692557280576 0.831242555766129 0.8234530109366733 0.9249370398051078 0.9897509486388876 0.7502969818954071 1.0274735764306544 1.0 16.367246070665132 -5.541960289503704 3.734418573862279 0.8974341057816215 1.1200617603861518 0.5315001955713542 0.08337709755543968 0.15727864102821482 4.762774825103612 0.022306494898464455 0.044217580092927804 2.8710430890066607e-06 5.541960289503704 0.22262765460453027 SRNS(ph)PLLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRNSPLLER 9 1 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 S(0.447)RNS(0.553)PLLER;S(0.056)RNS(0.944)PLLER 65.563 0.023969999999999998 200054000.0 22307.5 26013.0 34536.0 39431.0 40213.0 34608.0 38756.0 28619.0 34570.0 29644.0 True False 26083.719156791667 28595.398726072122 35359.469218509366 37221.80890702681 32333.55132143587 32793.09555609792 35084.75111085845 27867.78157433699 35075.52084998542 35018.222538225134 0.7448613112307241 0.8165862414877855 1.0097448315633877 1.0629268480545033 0.9233350232480037 0.9364580261120246 1.0018998272274013 0.7958079980763479 1.0016362427218497 1.0 15.095818236582845 -5.098144456085226 4.158917154700087 0.9608018261591972 0.7582089378381327 0.5453410589979061 0.06891506297870542 0.16797558297323043 4.945490432124047 0.018275439621400436 0.05739150974980998 7.977293004764667e-06 5.098144456085226 -0.20259288832106448 SRNS(ph)PLLER ddPTM_PC-9_Lapatinib_30min_R1 1 SRNSPLLER 9 1 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 S(0.019)RNS(0.981)PLLER 101.35 0.017022 94720000.0 368080.0 328880.0 295590.0 301590.0 244450.0 301970.0 266940.0 212570.0 319710.0 219200.0 True False 362831.1117023947 328118.4985663262 271287.731210397 323769.9346747465 230071.93160719145 289055.447026451 280760.84705254895 222446.77822493698 283700.89310444804 257088.42793435944 1.4113086093281249 1.2762865337917986 1.0552312034817177 1.2593718716791575 0.8949136040690796 1.1243425048297135 1.0920788979433709 0.8652539517715389 1.1035148310015859 1.0 17.971905147473244 -1.5228787452804076 0.4488944544319607 1.0042378587230518 10.52532404832658 0.5928502021429747 0.10339110420478186 57.74045005330249 0.6972696543702496 0.061931054130193196 503.5261555430757 0.029999999999995166 1.5228787452804076 9.521086189603528 SRPFTVAASFQS(ph)TSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRPFTVAASFQSTSVK 16 1 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 SRPFTVAAS(0.002)FQS(0.333)T(0.333)S(0.333)VK 52.823 0.037328 8737500.0 31274.0 27681.0 22810.0 30524.0 39613.0 29922.0 32874.0 32573.0 24712.0 25275.0 True False 36568.07051034419 30428.98674264414 23353.876907406724 28813.839240143214 31851.117014299823 28352.83764532945 29759.936732850696 31717.993263946308 25073.36624948913 29857.1574232101 1.2247673143163058 1.0191521688193101 0.7821868832446885 0.965056345844369 1.066783303005921 0.9496161085746484 0.9967438062176733 1.0623246149779029 0.8397774072758115 1.0 14.865789198516538 -4.8027786031549535 4.1638977518594436 0.9618382709955516 1.2403706303005118 0.47015331115886416 0.08465001804927849 0.18205555622257658 5.943682769399562 0.021427969170242974 0.142003995806493 1.5747854619976326e-05 4.8027786031549535 0.2785323593049601 SRPFTVAASFQSTS(ph)VKSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRPFTVAASFQSTSVKSPK 19 2 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 S(0.001)RPFT(0.004)VAAS(0.009)FQS(0.047)T(0.415)S(0.475)VKS(0.049)PK 49.141000000000005 0.021657 7695400.0 30055.0 22087.0 22671.0 39443.0 41115.0 40372.0 48241.0 50076.0 42801.0 38846.0 True False 35142.71788669166 24279.65139210221 23211.562620246295 37233.13658593136 33058.81089649706 38254.82124915586 43671.263245405185 48761.558059907744 43426.88365346331 45888.47229523318 0.7658288918531339 0.5291013227874299 0.5058255692390412 0.811383223794946 0.7204164628494542 0.8336477406141435 0.9516826571265412 1.0626101855426775 0.9463571455172288 1.0 15.485844157343909 -6.782387138933315 0.9528459919097529 1.0151872782397533 0.6098770664709583 0.7549542334409082 0.08861713640407347 0.2631208005715853 0.5139394318681874 0.054051257977581355 0.04850936641476565 1.650489862040907e-07 6.782387138933315 -0.405310211768795 SRPFTVAASFQSTSVKS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 SRPFTVAASFQSTSVKSPK 19 2 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 SRPFTVAASFQS(0.006)T(0.035)S(0.163)VKS(0.795)PK 66.779 0.0030779 13577000.0 79695.0 75544.0 80481.0 88562.0 80703.0 86433.0 73396.0 69689.0 58910.0 80003.0 True False 105036.35224102222 99962.12065656327 79413.76935464868 68145.39916926033 69498.78148518091 81028.33084641381 79928.1018131077 58920.16634390753 62023.86233285138 77202.11932101793 1.3605371609588255 1.2948105769079454 1.028647530055935 0.8826881926116767 0.9002185703762173 1.0495609648937994 1.0353096847089744 0.7631936384920819 0.8033958507660509 1.0 16.236352831860877 -5.308337917322809 2.478076952246537 0.9189423288879447 1.3565149820645797 0.77157011654089 0.08793014632589484 0.14809237029465236 1.7356777252114746 0.026713876695729385 0.08226587199204187 4.916568367965638e-06 5.308337917322809 0.43757265317663496 SRPLATGPSS(ph)QSHQEK ddPTM_PC-9_AZD4547_30min_R2 1 SRPLATGPSSQSHQEK 16 1 Q96RL1-2;Q96RL1-3;Q96RL1;D6RC40;D6RCQ3 Q96RL1-2 UIMC1 BRCA1-A complex subunit RAP80 1 S(0.008)RPLAT(0.115)GPS(0.017)S(0.789)QS(0.072)HQEK 64.422 0.014262 4990100.0 8697.8 6991.5 12737.0 18367.0 15756.0 13582.0 12261.0 12994.0 10917.0 14237.0 True False 11463.519474521174 9251.36564876578 12568.099057792038 14132.77191732125 13568.551368356926 12732.715392916998 13352.205247295693 10986.075872415086 11494.050332502784 13738.566963405541 0.8344043090560863 0.6733865091903687 0.9148042216680098 1.0286933094962323 0.9876249396679091 0.9267862817739463 0.9718775824917567 0.7996522418734011 0.8366265828975236 1.0 13.745943907533043 -5.351254529789369 6.854557884879911 0.9334862141594161 0.7548174371857782 0.46946220955575424 0.07639911501287233 0.20893898483100914 13.465394869178924 0.02128429523326437 0.04480008712162476 4.4539513626712385e-06 5.351254529789369 -0.17866877697363792 SRPT(ph)SEGSDIESTEPQK ddPTM_PC-9_AZD4547_30min_R2 1 SRPTSEGSDIESTEPQK 17 1 H0YA82;Q4G0J3;Q4G0J3-3;D6RFF0 H0YA82 LARP7 La-related protein 7 1 S(0.001)RPT(0.479)S(0.479)EGS(0.04)DIES(0.001)TEPQK 106.31 0.0068476 6825100.0 20590.0 22655.0 26863.0 32904.0 26400.0 33509.0 25707.0 28765.0 25894.0 30844.0 True False 27137.1917013947 29977.78570732871 26506.779068027623 25318.491161732385 22734.815697170787 31413.676932797505 27994.87319894222 24320.030203941813 27262.703976351273 29764.160948182922 0.9117405240698176 1.0071772478155083 0.8905602652187593 0.8506368180782888 0.76383190296378 1.0554195358466936 0.9405564379146822 0.8170910729276423 0.9159574168347466 1.0 14.861288604909685 -9.494071256523902 15.657083965964247 0.9999999006447735 0.9054172631205395 0.1087564741110506 0.08081532899957684 0.0 0.0 0.08096686294750988 0.019637348712205422 3.205743301554489e-10 9.494071256523902 -0.09458263752423401 SRPT(ph)SFADELAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRPTSFADELAAR 13 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;A0A0A0MT65;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 S(0.016)RPT(0.492)S(0.492)FADELAAR 158.65 0.0025906999999999996 10427000.0 18545.0 18276.0 22140.0 27488.0 44147.0 56513.0 55685.0 53175.0 49821.0 41875.0 True False 21684.302219554036 20090.320498123783 22667.90156641756 25947.93647729839 35496.712261891174 53549.35879454928 50410.113675512286 51779.21259356969 50549.53787292809 49466.60601768242 0.43836244216558395 0.4061390524941667 0.45824655037611944 0.52455461504723 0.7175894026204761 1.0825355346879355 1.01907362832802 1.0467508641094279 1.0218921802490062 1.0 15.59416729684602 -6.480032886607422 2.017610770348141 1.0403656632204406 0.439761835013873 0.9796222320745214 0.03922899598416657 0.04054384146922862 0.3297546756002222 0.014206319830954418 0.01583171716766135 3.311060477887002e-07 6.480032886607422 -0.6006038282065675 down SRPT(ph)SFADELAAR ddPTM_PC-9_Lapatinib_30min_R1 1 SRPTSFADELAAR 13 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;A0A0A0MT65;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3;A0A087WYF6 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 S(0.356)RPT(0.476)S(0.169)FADELAAR 66.738 0.026489 17562000.0 5687.3 6371.3 6207.1 6597.4 4863.0 7751.6 6156.9 9507.9 9661.0 8001.5 True False 5606.198059076915 6356.547646301509 5696.776198098897 7082.594804281233 4576.96790102586 7420.082137862162 6475.674156056934 9949.67174429544 8572.876445159893 9384.548613671437 0.597386010757064 0.6773418635224792 0.6070378483414554 0.7547080947466444 0.4877131644198763 0.7906701156678506 0.6900357622553261 1.0602184669596926 0.9135097273267786 1.0 13.196071639363543 -7.7109471432465355 6.492316832250326 0.9898200608616513 0.657247979712269 0.7588470560986459 0.08617286725013451 0.08779445124360975 8.26367259549838 0.039860115314683954 0.022411801649303353 1.945596860306409e-08 7.7109471432465355 -0.3325720811493823 SRPTSEGS(ph)DIESTEPQK ddPTM_PC-9_AZD4547_30min_R2 2 SRPTSEGSDIESTEPQK 17 1 H0YA82;Q4G0J3;Q4G0J3-3;D6RFF0 H0YA82 LARP7 La-related protein 7 1 SRPT(0.016)S(0.016)EGS(0.967)DIESTEPQK;SRPT(0.01)S(0.026)EGS(0.964)DIESTEPQK 104.42 0.00037265 34239000.0 138490.0 176535.0 189788.0 231106.0 212612.0 220726.0 171246.0 190801.0 184562.0 189949.0 True False 182526.93922905094 233596.4864199197 187271.28711472388 177828.0822521068 183094.49375026024 206923.9683269772 186486.56225254064 161317.08962079987 194317.57052920922 183298.94332597582 0.995788278519686 1.2744017078401568 1.0216713949173384 0.9701533409053006 0.998884611269406 1.1288879497738675 1.0173902744267107 0.8800764843140215 1.0601128790122814 1.0 17.483838943551007 -5.486133397523951 24.553769624049185 1.0070607762949333 1.1383304663572662 0.25440834831706993 0.08613977933452945 567.3646786956047 379119.77250672306 0.021904705024133338 0.04557245878094299 3.2648753313604717e-06 5.486133397523951 0.1312696900623329 SRPTSEGS(ph)DIESTEPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SRPTSEGSDIESTEPQK 17 1 H0YA82;Q4G0J3;Q4G0J3-3;D6RFF0 H0YA82 LARP7 La-related protein 7 1 S(0.008)RPT(0.005)S(0.005)EGS(0.981)DIESTEPQK;S(0.089)RPT(0.237)S(0.155)EGS(0.503)DIES(0.007)T(0.009)EPQK;SRPT(0.003)S(0.005)EGS(0.717)DIES(0.24)T(0.034)EPQK;S(0.003)RPT(0.226)S(0.226)EGS(0.54)DIES(0.003)T(0.001)EPQK 119.62 0.00020408 48446700.0 184693.0 202372.0 252434.0 235960.0 251402.0 205507.0 214198.0 190043.0 181011.0 175838.0 True False 215957.87704697222 222462.15473004527 258452.98392127617 222739.92619264193 202141.58280435778 194729.85114560285 193907.6147807738 185054.57261720297 183657.94343583222 207716.0374671575 1.0396783978758397 1.0709917127377289 1.2442610935236083 1.0723289781024246 0.9731630993409399 0.9374810607793925 0.9335225972208959 0.8909017082826953 0.8841779656270924 1.0 17.664253083402805 -6.305580802111555 2.641593500283178 0.9246080761315735 1.1185406679738186 0.6801838068901697 0.05813018438180027 0.1652146619928243 2.278030390508998 0.019940115492407384 0.024390032061128452 4.947880451908628e-07 6.305580802111555 0.1939325918422451 SRPTSEGS(ph)DIESTEPQK ddPTM_PC-9_Lapatinib_30min_R1 4 SRPTSEGSDIESTEPQK 17 1 H0YA82;Q4G0J3;Q4G0J3-3;D6RFF0 H0YA82 LARP7 La-related protein 7 1 SRPT(0.002)S(0.006)EGS(0.989)DIES(0.003)TEPQK;S(0.003)RPT(0.011)S(0.011)EGS(0.972)DIES(0.002)T(0.001)EPQK;S(0.012)RPT(0.111)S(0.111)EGS(0.766)DIES(0.001)TEPQK;S(0.004)RPT(0.271)S(0.271)EGS(0.454)DIESTEPQK 113.59 8.6885e-05 157337000.0 145037.0 170352.0 188474.0 146666.0 191136.0 170249.0 168823.0 159610.0 175807.0 148126.0 True False 142968.745783472 169957.56041039573 172978.3952506792 157452.30690343323 179893.75626783422 162967.84713980302 177563.82888271677 167026.06328495208 156005.76433021677 173729.3817345118 0.8229393575000037 0.9782890994807082 0.9956772626694762 0.906307875682464 1.0354826251712717 0.9380557595539353 1.0220713796936471 0.961415171212642 0.8979814627362243 1.0 17.406482242866183 -4.759672150640737 24.99819384344095 0.97077663206663 0.8229391727533129 0.5085182411561016 0.04354555354913861 36.44942291152035 515443.5935828482 0.010255141581912154 0.06421272489088925 1.7391131917049075e-05 4.759672150640737 -0.14783745931331715 SRPTSEGS(ph)DIESTEPQKQCSK ddPTM_PC-9_AZD4547_30min_R2 1 SRPTSEGSDIESTEPQKQCSK 21 2 H0YA82;Q4G0J3;Q4G0J3-3;D6RFF0 H0YA82 LARP7 La-related protein 7 1 S(0.004)RPT(0.07)S(0.136)EGS(0.79)DIESTEPQKQCSK 99.064 0.00069841 0.0 2632.0 1007.2 3495.8 6988.2 4309.1 2873.7 871.76 3173.7 2671.8 4796.9 True False 3468.921250999071 1332.7577031305007 3449.4434078848576 5377.178456613732 3710.855845480252 2694.007084716948 949.3449511771055 2683.27758937077 2813.0258934121925 4628.961991062724 0.7493950604253441 0.2879171843933253 0.7451872395031114 1.1616380663733277 0.8016604700243624 0.5819894589582607 0.20508808519275687 0.5796715536985299 0.6077012295290793 1.0 12.176473001206247 -6.8565881108941085 6.102850328847796 0.5407549203382348 0.7455626560531654 0.06033362419938493 0.26754702763917004 0.5165787543126228 27.52152158738156 0.10011317114668154 0.08847062637554609 1.3912715011081058e-07 6.8565881108941085 0.2048077357149306 SRPTSEGSDIES(ph)TEPQK ddPTM_PC-9_AZD4547_30min_R2 1 SRPTSEGSDIESTEPQK 17 1 H0YA82;Q4G0J3;Q4G0J3-3;D6RFF0 H0YA82 LARP7 La-related protein 7 1 S(0.012)RPT(0.051)S(0.051)EGS(0.232)DIES(0.575)T(0.078)EPQK 67.312 0.0089412 29768000.0 60984.0 76637.0 88553.0 96607.0 91016.0 94488.0 75356.0 94573.0 77384.0 89281.0 True False 80375.64345399983 101408.41153178323 87378.72936049775 74335.74871327134 78379.99945051863 88579.65042305579 82062.53801608448 79958.91592134156 81474.36025743285 86155.29936502155 0.9329158397264159 1.1770420656556193 1.0142002872080194 0.8628111011294465 0.9097525053965556 1.0281393144229327 0.9524955356304095 0.9280789053099654 0.9456685875147789 1.0 16.39465191810647 -5.528146922700833 24.965490300692245 0.9452428919092587 1.0651395127350325 0.28992722635412127 0.06948193359853755 138.8716949627906 658099.9961036248 0.0181646611407953 0.03159395882923139 2.963828550714817e-06 5.528146922700833 0.11989662082577379 SRQPS(ph)PLLLLPPPAGLTSDPGPSVR ddPTM_PC-9_AZD4547_30min_R2 2 SRQPSPLLLLPPPAGLTSDPGPSVR 25 1 I3L2J0 I3L2J0 CIC 1 S(0.25)RQPS(0.75)PLLLLPPPAGLTSDPGPSVR;S(0.123)RQPS(0.877)PLLLLPPPAGLTSDPGPSVR 88.045 3.7472000000000003e-06 33157000.0 18666.9 17464.1 31051.7 45189.0 35740.0 27285.0 28533.5 34689.0 25576.0 31549.0 True False 24602.585904359632 23109.028795910803 30639.934169179654 34771.37421309034 30778.117917306205 25578.864636705966 31072.926223286173 29328.61212391929 26927.895145561153 30444.479112768244 0.8081132153133619 0.7590548260101124 1.0064200492866846 1.1421241297739078 1.0109589263558145 0.8401807283994008 1.0206423998318421 0.96334747641056 0.884491899034257 1.0 14.893893009034729 -5.261986414571018 24.99696688665763 0.9850625208709924 0.783584006638543 0.5156292057675447 0.07750114062623278 38.25316631579314 1748097.7642877332 0.02151901569322907 0.049684836474751075 5.470330746995798e-06 5.261986414571018 -0.20147851423244945 SRQPS(ph)PLLLLPPPAGLTSDPGPSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRQPSPLLLLPPPAGLTSDPGPSVR 25 1 I3L2J0 I3L2J0 CIC 1 S(0.235)RQPS(0.765)PLLLLPPPAGLTSDPGPSVR;S(0.141)RQPS(0.859)PLLLLPPPAGLTSDPGPSVR 75.758 7.569199999999999e-05 18703100.0 28212.5 24157.5 26167.2 40621.7 44127.2 38626.9 45789.9 36474.6 34031.8 34431.5 True False 32988.31902772545 26555.696948644425 26791.12528765861 38345.79784632829 35480.79192975569 36601.23736522881 41452.34918183243 35517.1803980332 34529.4506931598 40673.658390395954 0.8110487311245844 0.6528966903777427 0.6586849166728669 0.9427673674759159 0.8723285126998453 0.899875713512686 1.0191448426881695 0.8732231572859862 0.8489388970556199 1.0 15.31180713932694 -5.764452697010343 24.99998839274273 0.9180586725555182 0.7020787487767516 0.6924569798007235 0.06552048256319944 42.10587398747269 349335.8286115055 0.018290046885741693 0.028500897177126863 1.7200746801229565e-06 5.764452697010343 -0.21597992377876662 SRQPS(ph)PLLLLPPPAGLTSDPGPSVR ddPTM_PC-9_Lapatinib_30min_R1 1 SRQPSPLLLLPPPAGLTSDPGPSVR 25 1 I3L2J0 I3L2J0 CIC 1 S(0.299)RQPS(0.701)PLLLLPPPAGLTSDPGPSVR 62.028 0.0010433 12615000.0 17785.0 11810.0 16031.0 12116.0 11866.0 13522.0 11275.0 12726.0 15738.0 12710.0 True False 17531.38263863045 11782.65467060423 14712.993061449544 13007.051057791161 11168.065209453594 12943.69558132156 11858.764331001299 13317.296418547083 13965.42071151293 14906.906564989546 1.1760577261418386 0.7904158129143337 0.9869917006124244 0.8725519946800768 0.7491873086320258 0.8683019193077393 0.7955214771958702 0.8933641839430435 0.9368423053185431 1.0 13.863693284630314 -4.752166368652701 24.99976884852535 0.8701702712653646 1.1760583232863584 0.5633027028522515 0.07878160336648546 266.21468118662597 717655.6467578099 0.019197657960639773 0.23546876681434958 1.7694309984179517e-05 4.752166368652701 0.3058880520209938 SRQT(ph)PS(ph)PDVVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRQTPSPDVVLR 12 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 2 S(0.334)RQT(0.67)PS(0.996)PDVVLR 70.47 0.032735 0.0 6337.1 9405.1 10926.0 10797.0 9748.9 9432.3 6906.4 8606.4 6525.6 7082.7 True False 7409.845866569742 10338.776171859487 11186.517277085739 10192.079094346289 7838.673028064209 8937.653583384843 6252.175793994041 8380.49111923456 6621.024554777695 8366.737443377655 0.8856314563133206 1.235699846185889 1.3370226271340646 1.2181664792664681 0.9368852651481954 1.0682364116085743 0.7472656858549676 1.0016438517343211 0.7913508221795932 1.0 13.030449447240763 -6.268814468746635 21.029444549542347 0.9226644588880712 1.185877434486733 0.41885474109291954 0.14076126296514738 60.9123892871753 173686.30570440614 0.04340945369880058 0.050452220172401134 5.384997812982736e-07 6.268814468746635 0.26321297559866186 SRS(ph)APPNLWAAQR ddPTM_PC-9_AZD4547_30min_R2 1 SRSAPPNLWAAQR 13 1 Q92934;F5H1R6;F5H3B1 Q92934 BAD Bcl2-associated agonist of cell death 1 S(0.06)RS(0.94)APPNLWAAQR 60.08 0.027766000000000002 35971000.0 17013.0 17617.0 20082.0 45637.0 21785.0 22458.0 19479.0 25691.0 18708.0 23203.0 True False 22422.78010761673 23311.350730788334 19815.69955865431 35116.09473462133 18760.528786472176 21053.697709772503 21212.593264176878 21721.04627044915 19696.86668686104 22390.670032443544 1.001434082817828 1.0411189436051151 0.8849980607968335 1.5683360383471754 0.8378725942228893 0.9402888649274989 0.9473853722751636 0.9700936255581398 0.879690811320999 1.0 14.45061008049655 SRS(ph)APPNLWAAQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SRSAPPNLWAAQR 13 1 Q92934;F5H1R6;F5H3B1 Q92934 BAD Bcl2-associated agonist of cell death 1 SRS(1)APPNLWAAQR;S(0.374)RS(0.626)APPNLWAAQR;S(0.001)RS(0.999)APPNLWAAQR;S(0.287)RS(0.713)APPNLWAAQR 141.82 3.719e-05 27456200.0 53290.0 40324.3 44652.0 70733.0 76283.0 79919.0 75637.0 89817.0 73772.0 59422.8 True False 62310.944474523305 44327.430009985386 45716.67302365303 66770.05932948003 61335.89375209747 75727.9069506412 68472.11579554155 87459.39891897804 74850.77593708767 70195.683249374 0.8876748767179924 0.6314837032429725 0.6512747067542893 0.9511989375796195 0.873784411132496 1.0788114517186718 0.9754462472042708 1.24593699883615 1.066315939559648 1.0 16.099094692896838 -6.367606786122298 1.1107983977121312 1.0963892167955482 0.7195464815188292 0.6365903110638718 0.10772467461646353 0.2924339678860356 0.7561809000427769 0.04754637907200772 0.0637897546618147 4.2893670754068643e-07 6.367606786122298 -0.3768427352767191 SRS(ph)APPNLWAAQR ddPTM_PC-9_Lapatinib_30min_R1 3 SRSAPPNLWAAQR 13 1 Q92934;F5H1R6;F5H3B1 Q92934 BAD Bcl2-associated agonist of cell death 1 S(0.014)RS(0.986)APPNLWAAQR;S(0.015)RS(0.985)APPNLWAAQR;S(0.14)RS(0.86)APPNLWAAQR 113.43 0.00016297 63421000.0 44780.3 21791.0 38665.5 22834.5 35428.2 31708.1 28070.3 37180.6 36811.8 30023.9 True False 44141.72471029875 21740.54427833506 35486.5718431462 24513.825303658974 33344.38293052113 30352.01847819125 29523.64278496724 38908.14641045351 32665.667438560897 35213.49111066797 1.253545823433734 0.6173924706871433 1.0077550030929907 0.6961486785453226 0.9469206795125011 0.8619428952046185 0.8384185110241176 1.1049215849736136 0.9276463766656976 1.0 15.103840644477609 -7.746667119696477 24.99657082204484 1.012213012166912 0.8767896796423925 0.09693569363959087 0.1677861475160813 464.53925500277137 786063.0778156015 0.07280966438272699 0.0418075658103689 1.7919788530900964e-08 7.746667119696477 -0.13542333252451944 SRS(ph)AQEPAR ddPTM_PC-9_AZD4547_30min_R2 1 SRSAQEPAR 9 1 M0R128;A0A1B0GX60;M0R1D6;M0QZD0;M0QYT3;M0QXK0;M0R080;P25685-2;P25685 M0R128 DNAJB1 DnaJ homolog subfamily B member 1 1 S(0.032)RS(0.968)AQEPAR 84.605 0.0061708 22598000.0 20884.0 8002.2 14360.0 36037.0 18498.0 24605.0 32209.0 44227.0 40655.0 34509.0 True False 27524.677585814825 10588.754658450047 14169.577017342675 27729.226416099867 15929.871998722163 23066.445460368337 35075.538602899185 37392.73338535494 42803.94030117253 33300.85041372211 0.8265457861842733 0.31797250000819177 0.4255019568960885 0.8326882368347455 0.4783623181033846 0.6926683605312213 1.0532925786317393 1.122876230510519 1.2853707869134336 1.0 15.023271399848802 -7.247369495669627 2.46483595943672 1.149663839666236 0.5660251350114194 0.7097503144724704 0.16457942816267537 0.15886836262747264 1.90124653820393 0.07666636493445456 0.05139011425109762 5.657577402360624e-08 7.247369495669627 -0.5836387046548166 SRS(ph)AVTLPR ddPTM_PC-9_AZD4547_30min_R2 1 SRSAVTLPR 9 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.27)RS(0.723)AVT(0.007)LPR 92.866 0.0031603 4097100.0 7396.0 8795.8 13920.0 17349.0 11900.0 14752.0 13164.0 12337.0 8339.8 13948.0 True False 9747.774153643286 11638.870338756207 13735.411704833574 13349.456089378047 10247.890408951986 13829.555107959923 14335.570497952902 10430.600126057021 8780.624801960857 13459.68476544078 0.7242200930791313 0.8647208713713925 1.0204853935435958 0.9918104563380447 0.7613767029124315 1.0274798666510248 1.0650747582707922 0.7749512940183215 0.6523648179715231 1.0 13.71635700103847 -7.821350946630127 24.999965563363077 0.7852425330116245 0.9242845993018913 0.12343201347053712 0.13352204269706144 134.49810076085583 56121.1391031701 0.07324820156685607 0.035187311159867896 1.5088603747383597e-08 7.821350946630127 0.13904206629026683 SRS(ph)AVTLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRSAVTLPR 9 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 S(0.009)RS(0.975)AVT(0.016)LPR;S(0.031)RS(0.943)AVT(0.026)LPR 72.531 0.015115 16390600.0 22472.7 22258.6 20792.9 27526.0 34111.0 31838.0 24648.0 22289.0 24664.0 19138.2 True False 26276.884253942964 24468.28670603731 21288.68159351238 25983.807460496053 27427.194417862363 30168.359232404255 22313.16300393331 21703.937367147624 25024.664340296207 22607.804162092147 1.1622926342401259 1.0822938190107265 0.941651893340813 1.1493291110538126 1.2131737439521515 1.3344223532769866 0.9869672810306417 0.9600196999025633 1.1069038001601479 1.0 14.464533253182392 SRS(ph)DIDVNAAAGAK ddPTM_PC-9_AZD4547_30min_R2 4 SRSDIDVNAAAGAK 14 1 E3W994;J3KR49;O75122;A0A0U1RQI6;B3KR06;E7ENG2;O75122-2;E7ERI8;E7EW49;O75122-3 E3W994;E7ERI8 CLASP2 CLIP-associating protein 2 1 S(0.373)RS(0.627)DIDVNAAAGAK;S(0.183)RS(0.817)DIDVNAAAGAK;S(0.042)RS(0.958)DIDVNAAAGAK;S(0.004)RS(0.996)DIDVNAAAGAK 149.24 0.00038688 114182000.0 130958.0 130447.0 188929.0 219244.0 191428.0 180885.0 168103.0 196790.0 157354.0 168890.0 True False 172599.91990438334 172611.441719881 186423.67801598422 168700.6830860339 164851.52648780364 169574.23235516038 183063.84134133792 166380.62728432842 165671.41119544202 162977.21250611526 1.0590432689963145 1.0591139648642858 1.1438634588807266 1.0351182259894394 1.0115004665552128 1.0404781732832593 1.1232480819026707 1.0208827646876428 1.016531137377415 1.0 17.31431073519601 -8.439556110310917 0.32983580506031296 0.9900964311610951 1.0775405365125676 0.23059186415401167 0.0398052803252265 2.8072422165067543 0.9188272295778492 0.08866148871783128 0.053515426420845474 3.6344934430594474e-09 8.439556110310917 0.08744410535147251 SRS(ph)DIDVNAAAGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRSDIDVNAAAGAK 14 1 E3W994;J3KR49;O75122;A0A0U1RQI6;B3KR06;E7ENG2;O75122-2;E7ERI8;E7EW49;O75122-3 E3W994;E7ERI8 CLASP2 CLIP-associating protein 2 1 S(0.247)RS(0.753)DIDVNAAAGAK;S(0.002)RS(0.998)DIDVNAAAGAK 132.25 3.0174e-05 23414000.0 109429.0 115972.0 106212.0 132733.0 154816.0 148904.0 135742.0 121211.0 124087.0 103911.0 True False 127953.16837873141 127484.93372775285 108744.49689125302 125296.40033619203 124480.91615595475 141095.21210948945 122883.53507302504 118029.33968367027 125901.53762545978 122749.24174097655 1.0423947762442076 1.038580213772477 0.8859076874847331 1.0207509110369126 1.014107414354806 1.14945893032257 1.0010940461231677 0.9615484218854391 1.02568077684044 1.0 16.905354587042673 -5.041014364765928 24.99420341922795 1.008236420246292 1.0414419262654067 0.0445966756404671 0.06140279479326803 1709.1501390581877 1041557.6906494424 0.016561448184864668 0.043824635841575775 9.098831767513236e-06 5.041014364765928 0.03320550601911476 SRS(ph)DIDVNAAAGAK ddPTM_PC-9_Lapatinib_30min_R1 5 SRSDIDVNAAAGAK 14 1 E3W994;J3KR49;O75122;A0A0U1RQI6;B3KR06;E7ENG2;O75122-2;E7ERI8;E7EW49;O75122-3 E3W994;E7ERI8 CLASP2 CLIP-associating protein 2 1 S(0.083)RS(0.917)DIDVNAAAGAK;S(0.009)RS(0.991)DIDVNAAAGAK;S(0.207)RS(0.793)DIDVNAAAGAK;S(0.089)RS(0.911)DIDVNAAAGAK;S(0.031)RS(0.969)DIDVNAAAGAK 144.17 3.1283e-05 223191000.0 558363.0 470919.0 483824.0 436320.0 466795.0 452947.0 428880.0 429319.0 458317.0 344185.0 True False 550400.6412287657 469828.6159886768 444045.858334648 468408.42832085286 439339.03585427976 433575.5126810275 451085.30787404306 449266.7280460645 406696.513168031 403676.91865231586 1.3634681989406037 1.163872875261756 1.1000030911281842 1.1603547457819599 1.0883432159585014 1.0740656516318268 1.1174414167151323 1.1129363787901256 1.0074802258345514 1.0 18.62284157352223 -1.5228787467054712 0.8083574061845344 1.07984907699145 74.68809578414616 0.7910656739667602 0.04418576211127131 231.73113091275474 0.7771695515198337 0.015348130585051025 31260.441844269604 0.029999999901555257 1.5228787467054712 73.6082467071547 SRS(ph)DIDVNAAASAK ddPTM_PC-9_AZD4547_30min_R2 5 SRSDIDVNAAASAK 14 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 S(0.21)RS(0.79)DIDVNAAASAK;S(0.224)RS(0.776)DIDVNAAASAK;S(0.083)RS(0.917)DIDVNAAASAK;S(0.001)RS(0.999)DIDVNAAASAK;S(0.1)RS(0.9)DIDVNAAASAK 194.67 6.8869e-07 250313000.0 633036.0 630498.0 875531.0 1149602.0 976709.0 959478.0 848729.0 1026766.0 767680.0 949737.0 True False 834328.280033224 834294.1484396082 863920.8868782065 884579.0200738466 841109.8145745436 899481.6889828589 924264.2367940666 868102.9074354437 808257.9975502179 916486.9967074452 0.9103547382893776 0.9103174965240951 0.9426439109140808 0.9651844742497921 0.9177542262970447 0.9814451183860989 1.0084859251844944 0.9472070095420608 0.881908854630727 1.0 19.805754886114393 -5.368812915495537 2.9415060546749707 0.956715917855847 0.9091776168919012 0.2164635546038769 0.03530079543559724 0.42812206463372204 7.021843808417438 0.00997326182775041 0.025415434932312787 4.277471105098046e-06 5.368812915495537 -0.047538300963945734 SRS(ph)DIDVNAAASAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SRSDIDVNAAASAK 14 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 S(0.059)RS(0.941)DIDVNAAASAK;S(0.084)RS(0.916)DIDVNAAASAK;S(0.069)RS(0.931)DIDVNAAASAK;S(0.066)RS(0.934)DIDVNAAASAK;S(0.02)RS(0.98)DIDVNAAASAK 176.44 0.00020969 116767000.0 428398.9 481848.2 500654.6 567435.1 649413.7 573518.4 547637.5 540848.7 495373.4 425952.8 True False 500918.3725060399 529682.9048721845 512592.104407145 535643.5509964161 522165.74734025093 543442.0854825581 495761.3114478478 526651.9947015654 502617.2988206007 503174.67079949105 0.9955158746566751 1.052681972307101 1.0187160327301266 1.0645280497631875 1.037742512973845 1.0800267124318608 0.9852668272433821 1.0466583976986985 0.9988922892759989 1.0 18.940699774969403 -7.27576497801571 24.997332689089333 1.011592582044225 1.0418773672570796 0.2770993778076901 0.026469683455994843 1218.822029167572 2126767.126880085 0.01057693247918158 0.0071664676954246 5.299501531344106e-08 7.27576497801571 0.030284785212854493 SRS(ph)DIDVNAAASAK ddPTM_PC-9_Lapatinib_30min_R1 4 SRSDIDVNAAASAK 14 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 S(0.073)RS(0.927)DIDVNAAASAK;S(0.07)RS(0.93)DIDVNAAASAK;S(0.003)RS(0.997)DIDVNAAASAK;S(0.003)RS(0.997)DIDVNAAASAK 189.84 1.2124e-06 231277000.0 954080.0 851290.0 888014.0 766828.0 787867.0 777613.0 661348.0 671714.0 787733.0 618305.0 True False 940474.6442431572 849318.8903081028 815004.9167531704 823223.0891832199 741526.2120661193 744356.304694438 695589.3634393835 702924.2846525187 699010.2143437669 725178.1954103737 1.2968876480227713 1.1711864693166605 1.1238684807559118 1.135201105594968 1.0225434476094448 1.0264460644369091 0.9591978466006604 0.969312493262071 0.963915102202158 1.0 19.46797602135252 -4.908917838371254 0.4566077015420152 0.9592298938276403 1.4772469585468146 0.9285272866639466 0.02822839399260471 1.083109964932583 0.1913693117567598 0.02073510475231249 0.3013072032692874 1.2333381391764421e-05 4.908917838371254 0.5180170647191743 SRS(ph)DNALHLASER ddPTM_PC-9_AZD4547_30min_R2 1 SRSDNALHLASER 13 1 A0A1X7SBR1;Q7Z3G6 A0A1X7SBR1 PRICKLE2 Prickle-like protein 2 1 S(0.099)RS(0.901)DNALHLASER 61.126999999999995 0.025796 3836200.0 12245.0 8179.4 19943.0 23301.0 18975.0 17159.0 16218.0 18496.0 16673.0 15662.0 True False 16138.655288177672 10823.231093115177 19678.54278947528 17929.31444686136 16340.648782341515 16086.045017454197 17661.370581570973 15637.868195797248 17554.300741395873 15113.678147141773 1.0678178489085886 0.7161215812420894 1.302035321772205 1.186297225090245 1.0811827950320474 1.0643368782136142 1.1685686574522567 1.034683155453764 1.1614843567854898 1.0 13.883567184915597 -5.261426615405319 24.999999999999748 1.1261012075793184 0.8919697260098933 0.4010027191323544 0.1138280615124767 1.0165055729546688 1984627.3784032192 0.02808060024019428 0.06519799749566806 5.477386468828058e-06 5.261426615405319 -0.2341314815694251 SRS(ph)ESDLSQPESDEEGYALSGR ddPTM_PC-9_Lapatinib_30min_R1 2 SRSESDLSQPESDEEGYALSGR 22 1 Q15751;H0YNB1 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 S(0.138)RS(0.431)ES(0.431)DLSQPESDEEGYALSGR;S(0.198)RS(0.603)ES(0.198)DLSQPESDEEGYALSGR 143.63 2.329e-06 11167500.0 24834.0 26001.0 31793.0 20054.6 27322.0 29751.0 25034.0 25592.0 33937.0 19846.6 True False 24479.862606002167 25940.796281996692 29179.10226452905 21529.482184184435 25714.97367711876 28478.619082968336 26330.138027697256 26781.097748189295 30114.657687546962 23277.0583660678 1.0516733781828618 1.1144361918090115 1.253556261519066 0.9249228079252961 1.1047346822227693 1.2234629752221238 1.1311626071308087 1.1505361771670222 1.2937484287725418 1.0 14.506621128996908 -6.5721340697859345 12.502260466229604 1.1670747031374702 1.0894750523483965 0.10421558654647545 0.10234998527684301 2.171372159631982 547.1333988855798 0.0331643348977565 0.03316605906487876 2.678341374209806e-07 6.5721340697859345 -0.07759965078907372 SRS(ph)ESETSTMAAK ddPTM_PC-9_AZD4547_30min_R2 1 SRSESETSTMAAK 13 1 A0A087WVF1;Q96B23-2;Q96B23 A0A087WVF1 C18orf25 Uncharacterized protein C18orf25 1 S(0.002)RS(0.991)ES(0.007)ETSTMAAK 131.86 0.00030489 6337600.0 13359.0 13404.0 16515.0 21626.0 18166.0 16568.0 14117.0 18758.0 12806.0 15843.0 True False 17606.88411553823 17736.580870493664 16296.00030929069 16640.45981836934 15643.964467985026 15532.000340881232 15373.385651747278 15859.382115958319 13482.899016032843 15288.341392233888 1.1516543007393925 1.1601376771651255 1.0659102836079177 1.0884411455399798 1.0232610632263737 1.0159375659135343 1.0055626871046057 1.0373513848934919 0.8819072435733175 1.0 13.90014427905436 -5.517373470412331 0.44560226217260446 0.9665214386240153 1.2328431740151582 0.7331275752608384 0.03950264847839723 1.3874847539032287 0.3452474384798718 0.030854356831573743 0.18352002376774823 3.0382711485517625e-06 5.517373470412331 0.2663217353911429 SRS(ph)ESETSTMAAK ddPTM_PC-9_Lapatinib_30min_R1 5 SRSESETSTMAAK 13 1 A0A087WVF1;Q96B23-2;Q96B23 A0A087WVF1 C18orf25 Uncharacterized protein C18orf25 1 S(0.083)RS(0.813)ES(0.05)ET(0.026)S(0.026)T(0.003)MAAK;S(0.067)RS(0.704)ES(0.225)ET(0.002)S(0.002)TMAAK;S(0.04)RS(0.931)ES(0.02)ET(0.007)S(0.002)TMAAK;S(0.001)RS(0.859)ES(0.006)ET(0.094)S(0.03)T(0.01)MAAK;S(0.171)RS(0.824)ES(0.005)ETSTMAAK 147.1 0.00051987 78543600.0 133425.0 138721.0 160369.0 139556.0 188366.0 212359.0 200762.0 222185.0 227212.0 197019.0 True False 131522.33503285138 138399.80004749267 147184.0798622422 149819.41378516838 177286.6822218046 203276.9006030073 211156.4740239898 232508.5262262211 201620.99191156926 231073.47163868425 0.5691797249599685 0.5989428343548676 0.6369579286556317 0.6483626732342171 0.7672307901229665 0.8797067840001089 0.9138066456809137 1.006210382253575 0.8725406273673506 1.0 17.81799211532347 -6.540409805448921 1.060268631268102 0.959727911705005 0.5870816724222224 0.9461172170936955 0.03672418016135786 0.09956837322218468 0.23933100929551035 0.017287012943313137 0.01961555156986824 2.8813113802012325e-07 6.540409805448921 -0.3726462392827826 SRS(ph)FDYNYR ddPTM_PC-9_AZD4547_30min_R2 3 SRSFDYNYR 9 1 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 1 S(0.246)RS(0.753)FDYNYR;S(0.01)RS(0.99)FDYNYR;S(0.292)RS(0.708)FDYNYR 92.19 0.0071551 24680300.0 87924.0 72217.6 96527.0 105080.0 104225.0 89664.0 64971.0 91420.0 68660.5 90508.0 True False 115882.00306718938 95560.52690786052 95246.98891037858 80855.42946981649 89755.15780445533 84057.29590564786 70753.29313449543 77293.13962260957 72289.7538568111 87339.34246849109 1.3268018717795529 1.0941292229482418 1.0905393402147525 0.9257618294869375 1.027660104457917 0.9624218997981663 0.8100964712439951 0.8849750574947844 0.8276883225093052 1.0 16.414344049423995 -1.5228787452803443 0.4295424609091659 0.8809731585696485 9.538091016276056 0.7856037010165124 0.06714434998555259 34.94728961590199 0.4396224011864481 0.04402685142997872 261.7397349169562 0.029999999999999537 1.5228787452803443 8.657117857706407 SRS(ph)FDYNYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRSFDYNYR 9 1 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 1 S(0.001)RS(0.999)FDYNYR;S(0.017)RS(0.983)FDYNYR 108.98 0.011579 34375000.0 102360.0 100104.0 95612.0 103165.0 101608.0 90268.0 101272.0 73767.0 81732.0 74969.0 True False 119687.52629784583 110041.66355571129 97891.75269052903 97384.9995154427 81698.64179913103 85534.187172268 91678.7830142135 71830.69441259706 82927.17587824707 88560.28624572257 1.3514807976766978 1.2425621937398181 1.1053685217199394 1.0996463950583308 0.9225200737545837 0.9658300667066697 1.035213264327514 0.8110937470695727 0.9363923649496156 1.0 16.434372264774346 -5.054266186953482 0.6491944836571867 0.9254754025661437 1.5373504870788435 0.8380846628631282 0.06095190277919456 0.9212369801305674 0.3726227936518616 0.029823242068195695 0.3970966575666426 8.82538810592919e-06 5.054266186953482 0.6118750845126998 SRS(ph)FDYNYR ddPTM_PC-9_Lapatinib_30min_R1 1 SRSFDYNYR 9 1 O75494-2;O75494;Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3 O75494-2;O75494-6 SRSF10 Serine/arginine-rich splicing factor 10 1 S(0.411)RS(0.589)FDYNYR 130.44 0.0061098 16838000.0 38465.0 43733.0 47527.0 35965.0 48282.0 47551.0 35953.0 39932.0 42209.0 38396.0 True False 37916.482046382895 43631.73892544752 43619.51351952542 38609.986075722925 45442.14768606423 45517.35457679494 37814.470420619946 41787.38649893306 37454.9779395253 45032.697440545955 0.8419767014055024 0.9688901932435195 0.9686187148152455 0.8573767122588524 1.0090922877995228 1.0107623385627487 0.8397114223624775 0.9279343426873887 0.8317285010291672 1.0 15.458685276672783 -10.57029041232382 5.253588667561689 1.0000007711725103 0.9220782251241229 0.11587195134262218 0.06736311560716728 94947383.22151567 15.52149860333266 885.7566614528239 0.0162316150910402 2.6897355786963356e-11 10.57029041232382 -0.07792254604838744 SRS(ph)FSGLIK ddPTM_PC-9_AZD4547_30min_R2 1 SRSFSGLIK 9 1 Q14CB8-4;Q14CB8-6;Q14CB8-7;Q14CB8-3;Q14CB8;Q14CB8-2 Q14CB8-4 ARHGAP19 Rho GTPase-activating protein 19 1 S(0.034)RS(0.954)FS(0.012)GLIK 64.945 0.024755000000000003 8608000.0 36486.0 23013.0 36109.0 64272.0 46102.0 38532.0 36547.0 37460.0 40918.0 43371.0 True False 48087.789044054785 30451.502206257155 35630.17106679851 49455.08339250134 39701.53307844575 36122.587948746725 39799.61219907965 31671.417745164646 43080.84194424737 41852.59449110497 1.148979881146317 0.727589354412164 0.8513252643004265 1.1816491664097946 0.948603869394133 0.863090768636194 0.9509473112243582 0.7567372615787499 1.029346984770644 1.0 15.353029439444066 -6.540374738592358 23.52845390757741 0.9066525257472814 0.9648624021691486 0.028152553040546535 0.14148740242173474 520.3271610471169 699722.4579320109 0.04698908505656771 0.047002133543498525 2.8815440394137096e-07 6.540374738592358 0.05820987642186726 SRS(ph)FSGLIK ddPTM_PC-9_Lapatinib_30min_R1 2 SRSFSGLIK 9 1 Q14CB8-4;Q14CB8-6;Q14CB8-7;Q14CB8-3;Q14CB8;Q14CB8-2 Q14CB8-4 ARHGAP19 Rho GTPase-activating protein 19 1 S(0.043)RS(0.954)FS(0.003)GLIK;S(0.149)RS(0.835)FS(0.015)GLIK 89.663 0.0043275 12631300.0 52755.0 40378.0 51224.0 48383.0 58262.0 64839.0 54571.0 45401.0 72571.0 55032.0 True False 52002.70402591787 40284.507221816944 47012.56045035812 51941.2472209566 54835.14370749916 62065.98711709127 57396.41936204627 47510.496204499126 64397.28977349118 64544.207874469306 0.8056912577973976 0.6241382232185024 0.7283776809499602 0.8047390917241722 0.8495749737009229 0.9616042889208916 0.8892574756463876 0.7360923275548026 0.9977237601046424 1.0 15.978000015039942 -6.0485152312561565 1.8854535885670152 0.8975903060520306 0.7076168317505819 0.5082430342926841 0.08298966982182114 0.29021589188848906 2.0598978750447254 0.02698322883645603 0.04185996392695798 8.943031670406513e-07 6.0485152312561565 -0.18997347430144873 SRS(ph)FTLDDESLK ddPTM_PC-9_AZD4547_30min_R2 2 SRSFTLDDESLK 12 1 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 S(0.252)RS(0.747)FT(0.001)LDDESLK;S(0.077)RS(0.922)FTLDDESLK 114.54 0.00036053 67242000.0 251690.0 228294.0 266364.0 362060.0 352720.0 308480.0 298718.0 319050.0 300030.0 309130.0 True False 331722.184522779 302085.570967508 262831.8393208542 278592.66077123804 303750.9163903826 289190.69683456287 325303.3233065556 269748.15353963646 315888.97327661485 298307.45279184915 1.1120144046627147 1.0126651819802006 0.8810770125285846 0.9339111650208499 1.0182478297058564 0.9694383902515245 1.0904968020813863 0.9042622000056412 1.0589375837587056 1.0 18.18644049626524 SRS(ph)FTLDDESLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SRSFTLDDESLK 12 1 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 S(0.002)RS(0.985)FT(0.011)LDDES(0.002)LK;S(0.286)RS(0.694)FT(0.019)LDDES(0.001)LK;S(0.403)RS(0.552)FT(0.04)LDDES(0.005)LK;S(0.003)RS(0.991)FT(0.003)LDDES(0.003)LK 139.58 0.00035163 89355000.0 136992.0 129095.0 154805.0 209981.0 251488.0 294037.0 354158.0 420082.0 345092.0 272508.0 True False 160182.03988466677 141910.69844086704 158496.138301232 198216.4453375873 202210.731721714 278617.18209744437 320609.59035812365 409055.29261366994 350138.31765007647 321911.5432278589 0.4975964461494473 0.4408375574790068 0.492359288244111 0.6157481752596974 0.6281561999738016 0.8655085161088198 0.99595555705558 1.2707071281508162 1.0876848780853994 1.0 18.296304784893294 -6.887268275986673 1.1941993308215908 1.1392728972668058 0.4878036993737833 0.922793153950609 0.0768261467654445 0.1116118733123877 0.3322365678343756 0.041471072833871886 0.03318818204566026 1.2963782140972447e-07 6.887268275986673 -0.6514691978930225 down SRS(ph)FTLDDESLK ddPTM_PC-9_Lapatinib_30min_R1 3 SRSFTLDDESLK 12 1 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 S(0.018)RS(0.979)FT(0.003)LDDESLK;S(0.013)RS(0.979)FT(0.008)LDDESLK;S(0.493)RS(0.507)FTLDDESLK 118.2 0.0013189 140539000.0 327939.0 258722.0 332650.0 330340.0 413458.0 440898.0 448200.0 439360.0 494980.0 486930.0 True False 323262.5297233529 258122.94510483174 305300.80106613395 354634.305581935 389139.2133297032 422041.82032343664 471405.60294055694 459774.26956253604 439230.1400295256 571095.201706558 0.5660396528588814 0.45197883703715885 0.5345882790712092 0.6209723081584466 0.6813911448859484 0.7390043184783954 0.8254413651732555 0.805074649880842 0.7691014365328397 1.0 19.123371737680635 -6.3944858116278285 0.25378837234808377 1.0095054835087374 0.3035143418523347 0.8973113313346097 0.049278719815229535 1.2525312202226833 0.14446311779728585 0.08936990213559362 0.281262476662646 4.0319411855364367e-07 6.3944858116278285 -0.7059911416564026 SRS(ph)GDVLAK ddPTM_PC-9_AZD4547_30min_R2 1 SRSGDVLAK 9 1 P85299;P85299-5;P85299-2;P85299-4;P85299-3;B1AHG4 P85299 PRR5 Proline-rich protein 5 1 S(0.01)RS(0.99)GDVLAK 90.434 0.005218100000000001 0.0 55063.0 48623.0 69991.0 89617.0 71892.0 69364.0 64210.0 70548.0 53453.0 68376.0 True False 72571.8886184506 64339.43387541138 69062.87360869294 68957.18521884795 61911.03674625013 65026.65811473231 69924.56560874774 59646.427631763865 56278.4164535377 65982.17705203463 1.0998710842962822 0.9751032286290318 1.046689828894685 1.0450880571046812 0.9382993940534285 0.9855185297000918 1.0597492949285998 0.9039778663975532 0.8529336097709479 1.0 16.009788759306772 -6.906272596153927 0.638518783484501 0.9272474517062396 1.042690658109971 0.3063251609368708 0.060279282360741496 1.0314358287773338 0.9021701443494482 0.05073221949378727 0.047730915252133056 1.2408731969767445e-07 6.906272596153927 0.11544320640373151 SRS(ph)GEGEVSGLMR ddPTM_PC-9_AZD4547_30min_R2 1 SRSGEGEVSGLMR 13 1 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 S(0.116)RS(0.884)GEGEVSGLMR 116.87 0.00012613 11705000.0 15612.0 6243.3 15123.0 18793.0 18797.0 16785.0 8435.8 19962.0 15760.0 16380.0 True False 20576.29125022702 8261.324630614228 14922.45913880734 14460.564198955639 16187.361009837845 15735.431296577226 9186.569857689998 16877.331581125898 16593.041425322324 15806.541185683966 1.3017579879438161 0.5226522699410379 0.944068595621834 0.9148468364510142 1.0240925462237613 0.9955012365911434 0.5811878607579439 1.06774349826841 1.049757896455595 1.0 13.948234088790135 SRS(ph)LGGAVGSVASGAR ddPTM_PC-9_AZD4547_30min_R2 2 SRSLGGAVGSVASGAR 16 1 Q8NHG8 Q8NHG8 ZNRF2 E3 ubiquitin-protein ligase ZNRF2 1 S(0.208)RS(0.792)LGGAVGSVASGAR;S(0.318)RS(0.682)LGGAVGSVASGAR 69.485 0.010103000000000001 12489200.0 17902.4 15985.0 28617.0 54972.0 49553.0 23315.8 27730.0 42377.0 25526.0 31088.0 True False 23594.99080694748 21151.83864628777 28237.519881984368 42299.05470893363 42673.421297041845 21857.859340168903 30197.916279871934 35828.608376584154 26875.252247638164 29999.61858245076 0.7865096931849036 0.7050702524151831 0.9412626298689948 1.4099864167499057 1.4224654616777372 0.7286045747580058 1.0066100072864652 1.1943021301458563 0.8958531313914673 1.0 14.87265653784711 -5.521391810731326 24.987806896832893 1.102949866707432 0.765134030293521 0.31848067776784217 0.20289775007511499 64.33057261429025 1081069.1185117597 0.05846939248997476 0.10313432242349971 3.0102889836062115e-06 5.521391810731326 -0.337815836413911 SRS(ph)LGGAVGSVASGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRSLGGAVGSVASGAR 16 1 Q8NHG8 Q8NHG8 ZNRF2 E3 ubiquitin-protein ligase ZNRF2 1 S(0.274)RS(0.726)LGGAVGSVASGAR;S(0.249)RS(0.751)LGGAVGSVASGAR 53.861000000000004 0.034261 7775200.0 13289.8 11958.0 19761.1 28346.0 33217.0 28319.0 19609.5 30865.0 27462.0 19759.2 True False 15539.500654485257 13145.11121233115 20232.279568389073 26757.865518971932 26708.367300229653 26833.901787249695 17751.946199514376 30054.826454170718 27863.57979700027 23341.386546258862 0.6657488244620119 0.5631675387526641 0.8667985309395377 1.1463700095939957 1.1442493892681986 1.1496275824946915 0.7605352048959424 1.2876195848351555 1.1937414147089829 1.0 14.510602643422335 -5.509829705011032 3.186941181834632 1.0987905117780228 0.6180192629127094 0.670387926165499 0.13556724233699516 0.14357391934353375 2.9779722907813917 0.038451396304648715 0.08235483442145845 3.0915074327589587e-06 5.509829705011032 -0.4807712488653134 SRS(ph)PAPPADK ddPTM_PC-9_AZD4547_30min_R2 1 SRSPAPPADK 10 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 S(0.162)RS(0.838)PAPPADK 69.314 0.018262 8334000.0 51170.0 70072.0 65297.0 65581.0 65606.0 76849.0 71877.0 94728.0 86717.0 67125.0 True False 67440.9955978809 92721.40366735536 64431.119115698144 50462.31366634976 56497.73934199192 72043.6198814813 78273.91375580078 80089.96423288705 91300.68358373582 64774.974181259946 1.0411582011466438 1.4314386819806808 0.9946915445369443 0.7790402744915182 0.8722155439829922 1.112213795406255 1.2083974520277958 1.2364337499968914 1.4095055187246996 1.0 15.983148914909266 -7.157810482878171 3.4170821679621652 1.2351371709827654 1.0289750287685135 0.18506850542057318 0.18387631804905377 0.4498205995390827 9.833652520847997 0.0825029344182407 0.06158954981115382 6.953276779989926e-08 7.157810482878171 -0.2061621422142519 SRS(ph)PAPPADK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SRSPAPPADK 10 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 S(0.051)RS(0.949)PAPPADK;S(0.011)RS(0.989)PAPPADK;S(0.005)RS(0.995)PAPPADK 78.529 0.0095646 23470700.0 119974.0 202014.0 189675.0 154971.0 191430.0 122669.0 179061.0 107349.0 116507.0 132963.0 True False 140283.22860548797 222068.61485598484 194197.57134644286 146288.4772927609 153920.66569175344 116236.0216935674 162099.04579062408 104531.2024956675 118210.6944654106 157068.13936547108 0.8931361202355147 1.4138361589632675 1.2363906017539168 0.9313695182469327 0.9799610940421596 0.7400356441678205 1.0320300886320868 0.6655149982546175 0.7526077213555974 1.0 17.261031039912687 -5.902247351615195 2.9083930037225763 0.8507996925815723 1.2051638958158513 0.422866983525507 0.1651789537192531 0.22741391596122365 3.8758911545084893 0.048321439325351705 0.07695737753123708 1.252427653925293e-06 5.902247351615195 0.354364203234279 SRS(ph)PAPPADK ddPTM_PC-9_Lapatinib_30min_R1 2 SRSPAPPADK 10 1 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 S(0.098)RS(0.902)PAPPADK;S(0.04)RS(0.96)PAPPADK 68.168 0.019672 11563900.0 43802.0 64704.0 63775.0 60431.0 74674.0 67578.0 76559.0 79601.0 68386.0 57890.0 True False 43177.375447696984 64554.181863401915 58531.66567861916 64875.29733190636 70281.82213473269 64687.84647201219 80522.85041393596 83299.5530577374 60683.64854349498 67896.20936642369 0.6359320476151535 0.9507774066592518 0.862075603701736 0.9555069117597713 1.0351361702011121 0.9527460674999316 1.1859697494946817 1.2268660332447225 0.8937707879389288 1.0 16.051043410854234 -3.9806295343622238 0.5114081168908768 1.076571026937042 1.931556741118008e-12 0.5456838760226066 0.10608271034720665 7.232710813180852 0.7822793434372673 0.06129915662389554 5.56113809557273 0.00010456117757118187 3.9806295343622238 -1.0765710269351105 SRS(ph)PAPPADKEAFAAEAQK ddPTM_PC-9_AZD4547_30min_R2 2 SRSPAPPADKEAFAAEAQK 19 2 Q9Y618;Q9Y618-4;Q9Y618-5 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 S(0.214)RS(0.786)PAPPADKEAFAAEAQK;S(0.05)RS(0.95)PAPPADKEAFAAEAQK 49.395 0.021106 7212400.0 45283.0 38781.0 55710.0 62211.0 62822.0 51342.0 41587.0 51605.0 42166.0 45072.0 True False 59682.052055087785 51316.19984621123 54971.24899973265 47869.215100368754 54100.24968665391 48131.57662370379 45288.162435305945 43630.633014928484 44394.80867640489 43494.04299884907 1.372189107751309 1.1798443259820466 1.2638799525072268 1.10059244438682 1.2438542374201795 1.1066245698285035 1.041249773825449 1.003140430428209 1.0207100930483666 1.0 15.408530200636696 -5.9884391281997535 0.3583129275178469 0.9706213918235078 1.395920432934879 0.7607776049798687 0.05912880125507588 1.3354562287414442 0.25589238899737227 0.06141917125236595 0.22866473252296196 1.0269773652955923e-06 5.9884391281997535 0.4252990411113713 SRS(ph)PASAEAPGDSGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRSPASAEAPGDSGER 16 1 H7BY64;Q8NB15;Q8NB15-1 H7BY64 PRAP1;ZNF511 Zinc finger protein 511 1 S(0.146)RS(0.721)PAS(0.133)AEAPGDS(0.001)GER 104.16 0.0061526 2256600.0 4418.5 4077.3 4106.6 4501.1 5703.5 4132.1 4978.1 3435.3 2963.1 3222.9 True False 5166.464780647048 4482.06739806304 4204.516918367229 4248.91795976309 4585.940117917326 3915.405401853685 4506.538329677069 3345.1270150012183 3006.4297318655426 3807.1862575376394 1.3570296883737296 1.1772650705463228 1.1043633365830043 1.1160257661024306 1.2045484007612903 1.0284249671530485 1.1836926340955398 0.8786349783592501 0.7896723534114668 1.0 11.894509436714273 -7.764798617390664 24.951002389856455 0.8756151456347406 1.1594106724638165 0.6495978082916182 0.09323930647639583 51.5509122162566 382884.787743731 0.04828960475758218 0.024693713132228526 1.7187051670169434e-08 7.764798617390664 0.28379552682907583 SRS(ph)PAVNGENK ddPTM_PC-9_Lapatinib_30min_R1 1 SRSPAVNGENK 11 1 Q8IZD2-6;Q8IZD2-5;Q8IZD2-2;Q8IZD2-7;Q8IZD2;Q8IZD2-8 Q8IZD2-6 KMT2E Histone-lysine N-methyltransferase 2E 1 S(0.008)RS(0.992)PAVNGENK 64.374 0.039221 0.0 4873.1 8090.6 9924.0 7220.9 7136.3 7385.1 6005.4 6835.4 7745.1 5956.7 True False 4803.608700382906 8071.8667127849785 9108.087027747817 7751.949074216259 6716.556864505618 7069.256488508936 6316.330227352127 7152.997637854525 6872.765278481307 6986.307658196165 0.6875747441135706 1.1553838032476658 1.303705401101601 1.1095917118854424 0.9613886466373862 1.0118730571814223 0.9041013560205816 1.0238595246321287 0.9837478700810359 1.0 12.770314461202569 -6.26258047552591 24.909004004854065 0.9797372649937114 1.0877040126534667 0.06103917162750627 0.14875593039879617 243.23376715216472 5309574.341653388 0.04648236595062007 0.05578884384000425 5.462853128799864e-07 6.26258047552591 0.10796674765975534 SRS(ph)PHEAGFCVYLK ddPTM_PC-9_AZD4547_30min_R2 1 SRSPHEAGFCVYLK 14 1 Q9NTZ6 Q9NTZ6 RBM12 RNA-binding protein 12 1 S(0.115)RS(0.884)PHEAGFCVYLK 62.708999999999996 0.022293 6205800.0 15413.0 21053.0 21876.0 38437.0 33343.0 32090.0 25742.0 36756.0 23070.0 27488.0 True False 20314.013389684147 27857.970536146153 21585.909946475516 29575.94349573024 28713.899992074446 30083.40722711726 28032.988131138205 31076.204768854015 24289.433101661536 26525.65348669602 0.7658251812673595 1.0502274920434422 0.8137748597712008 1.1149939627524765 1.0824954795732344 1.1341250175874322 1.0568255423074946 1.1715528435308984 0.9156959361564433 1.0 14.695100673400228 -5.769751074359779 24.99999997079538 1.078002733344342 0.8939710024403958 0.44618672634367174 0.09666187099144673 155.27829212054135 467048.59630889696 0.02526278214593631 0.03818108038996297 1.699217317980511e-06 5.769751074359779 -0.1840317309039462 SRS(ph)PLELEPEAK ddPTM_PC-9_AZD4547_30min_R2 3 SRSPLELEPEAK 12 1 A0A087WTQ7;A0A087WV56;A0A087WW71;A0A087X0X5;Q92466-3;Q92466-2;Q92466-5;Q92466-4;Q92466 A0A087WTQ7 DDB2 DNA damage-binding protein 2 1 S(0.005)RS(0.995)PLELEPEAK;S(0.01)RS(0.99)PLELEPEAK;S(0.088)RS(0.912)PLELEPEAK 118.52 0.00041429 429127000.0 388450.0 387147.0 714910.0 898650.0 863310.0 757750.0 508730.0 863740.0 556060.0 624090.0 True False 511969.0197380661 512284.69667778333 705429.8262861036 691480.1265040967 743454.3083153224 710367.7727126251 554005.984459404 730268.8297706487 585452.1963810112 602240.7990582115 0.8501068352371459 0.8506310058682471 1.1713418077773206 1.1481788141644311 1.2344801439522888 1.179541096889323 0.9199077600284845 1.2125861132501292 0.9721231063995424 1.0 19.199980921797213 -5.253754637881382 24.766121205725664 1.1146132314382413 0.8503688720900752 0.4973371676318761 0.10192014651363066 395.5821951521853 1274859.8080991697 0.025679502778630958 0.06527316855861852 5.575006295204858e-06 5.253754637881382 -0.26424435934816615 SRS(ph)PLELEPEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SRSPLELEPEAK 12 1 A0A087WTQ7;A0A087WV56;A0A087WW71;A0A087X0X5;Q92466-3;Q92466-2;Q92466-5;Q92466-4;Q92466 A0A087WTQ7 DDB2 DNA damage-binding protein 2 1 S(0.407)RS(0.593)PLELEPEAK;S(0.297)RS(0.703)PLELEPEAK;S(0.05)RS(0.95)PLELEPEAK;S(0.057)RS(0.943)PLELEPEAK 121.99 0.00033573 346889800.0 725622.0 788109.0 1380586.0 981818.0 1550593.0 1391880.0 1069357.0 1006364.0 1125485.0 831127.0 True False 848455.4729122273 866347.2530890697 1413504.4061415624 926809.9205569014 1246765.432674986 1318887.3625352986 968059.763485762 979948.0113307989 1141943.0889165713 981803.7459022889 0.8641803175567302 0.8824036949389378 1.4397015819516308 0.9439869469077574 1.2698723526759355 1.343330953909965 0.9860012935641267 0.9981098721824649 1.163107284610238 1.0 19.90507514550454 -5.051343088918083 24.93988056838471 1.1431913429090284 0.8687351626568888 0.31762309534401745 0.15823499997434995 332.525619087589 161523.92452280765 0.03966227196215521 0.10493922003210202 8.884989339928983e-06 5.051343088918083 -0.2744561802521396 SRS(ph)PLELEPEAK ddPTM_PC-9_Lapatinib_30min_R1 5 SRSPLELEPEAK 12 1 A0A087WTQ7;A0A087WV56;A0A087WW71;A0A087X0X5;Q92466-3;Q92466-2;Q92466-5;Q92466-4;Q92466 A0A087WTQ7 DDB2 DNA damage-binding protein 2 1 S(0.034)RS(0.966)PLELEPEAK;S(0.108)RS(0.892)PLELEPEAK;S(0.019)RS(0.981)PLELEPEAK;S(0.053)RS(0.947)PLELEPEAK;S(0.155)RS(0.845)PLELEPEAK 139.77 3.8214000000000004e-05 214737400.0 471206.0 454244.0 525390.0 407430.0 468937.0 464639.0 416805.0 472522.0 484744.0 375223.0 True False 464486.51603140373 453192.2259266692 482194.46226404986 437393.761346637 441355.0476256138 444767.473096411 438385.12345747225 494477.0971463697 430147.02613938414 440079.7955967796 1.0554597613406151 1.0297955744869136 1.0956977963738592 0.9938964835990706 1.0028977745436025 1.0106518807419336 0.9961491707725203 1.1236078140688632 0.977429617181298 1.0 18.747405612446386 -5.774314619137974 24.9998481238691 1.0186335395438977 1.0572655086263254 0.20067372804163153 0.04090020161385463 415.2809135505184 806351.0751782525 0.011510208453827747 0.017188987088096474 1.6814555105895338e-06 5.774314619137974 0.03863196908242772 SRS(ph)PLELEPEAKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRSPLELEPEAKK 13 2 A0A087WTQ7;A0A087WV56;A0A087WW71;A0A087X0X5;Q92466-3;Q92466-2;Q92466-5;Q92466-4;Q92466 A0A087WTQ7 DDB2 DNA damage-binding protein 2 1 S(0.13)RS(0.87)PLELEPEAKK 50.354 0.033573 11391000.0 96585.0 41461.0 74837.0 134400.0 125750.0 129620.0 101990.0 103080.0 105940.0 99095.0 True False 112934.93285929505 45576.974073796824 76621.39790090287 126870.00373067874 101110.19020392832 122822.49901703112 92328.76885634384 100374.25922228809 107489.17208121097 117060.13906441173 0.9647599410176096 0.3893466592305886 0.6545472994760612 1.0838019221971809 0.8637456867217026 1.0492256373405526 0.7887293624821377 0.8574589097921511 0.9182388893461472 1.0 16.836890372102886 -5.702376961259397 10.406972132398453 0.9266915843968913 0.6406997252983238 0.37904832953565726 0.1553378366021793 0.4407851448867267 74.93514102299676 0.04028216923727847 0.06975310974951601 1.98437176395688e-06 5.702376961259397 -0.2859918590985675 SRS(ph)PLGFYVHLK ddPTM_PC-9_AZD4547_30min_R2 1 SRSPLGFYVHLK 12 1 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 1 S(0.006)RS(0.993)PLGFY(0.001)VHLK 88.803 0.0036976 4670700.0 13342.0 13589.0 20806.0 28089.0 21703.0 17918.0 20639.0 20320.0 20580.0 20720.0 True False 17584.478469160196 17981.378502621483 20530.09884560109 21613.515020723957 18689.913071049166 16797.58462746922 22475.831016959117 17180.010907147513 21667.816785097293 19994.599106677168 0.8794614173228352 0.8993117794803211 1.0267822193416767 1.080967660587211 0.9347480772849153 0.8401060975440958 1.1240951067357656 0.8592325765316431 1.0836834821990182 1.0 14.287322734835682 -5.163474754760099 5.858347407533789 0.9886983087724994 0.8855254761127276 0.1790361593152281 0.08905585480254663 0.3971315783807525 19.306129661076003 0.022097689481799587 0.060810231945041135 6.863177724326123e-06 5.163474754760099 -0.10317283265977184 SRS(ph)PLGFYVHLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRSPLGFYVHLK 12 1 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 1 S(0.205)RS(0.795)PLGFYVHLK;S(0.326)RS(0.674)PLGFYVHLK 90.229 0.0033318000000000006 6919700.0 64413.0 59795.0 64501.0 68821.0 82870.0 69582.0 69680.0 81745.0 60766.0 58941.0 True False 75316.84868525925 65731.0524286119 66038.94846140471 64965.182490692474 66632.21838727241 65932.99742788967 63079.40596048657 79599.28036598698 61654.58779202239 69626.53672330074 1.081726195639632 0.9440517297281397 0.948473837264759 0.9330520452118318 0.9569945817077202 0.946952132488086 0.9059678813433908 1.1432319358683372 0.8855041582355407 1.0 16.087349643993058 SRS(ph)PLLVTVVESDPRPQGQPR ddPTM_PC-9_AZD4547_30min_R2 1 SRSPLLVTVVESDPRPQGQPR 21 2 A0A2R8YH03;Q5VWN6;Q5VWN6-2 A0A2R8YH03 FAM208B Protein FAM208B 1 S(0.267)RS(0.733)PLLVTVVESDPRPQGQPR 71.637 0.0007532999999999999 10105000.0 22469.0 24901.0 33207.0 49968.0 34819.0 39930.0 27447.0 37432.0 34084.0 36494.0 True False 29613.674615766784 32949.76128440489 32766.653482931626 38448.6495979043 29984.982869689014 37433.17078774672 29889.72982811554 31647.74450178864 35885.61065613489 35216.35616790909 0.8409068352946818 0.9356380065928106 0.9304384964390564 1.0917838692505228 0.8514504659915052 1.062948438199228 0.8487456704947959 0.8986660729717303 1.01900408108763 1.0 15.103958020960325 -4.691313617960139 2.1532068805637428 0.9589183785974704 0.7898455270337403 0.17697146443279477 0.07865548173226539 1.6680509188433 7.174820365999622 0.02000669530921654 0.5980527510232578 2.0355715953598687e-05 4.691313617960139 -0.1690728515637301 SRS(ph)PLLVTVVESDPRPQGQPR ddPTM_PC-9_Lapatinib_30min_R1 2 SRSPLLVTVVESDPRPQGQPR 21 2 A0A2R8YH03;Q5VWN6;Q5VWN6-2 A0A2R8YH03 FAM208B Protein FAM208B 1 S(0.236)RS(0.764)PLLVTVVESDPRPQGQPR;S(0.179)RS(0.821)PLLVTVVESDPRPQGQPR 93.427 0.00012749999999999998 20652700.0 50443.0 33495.0 43285.0 34216.0 43138.0 38171.0 38164.0 33974.9 38215.0 31823.0 True False 49723.67356988675 33417.44438542668 39726.274384931916 36732.35878122998 40600.707652571116 36538.51531094701 40139.94518211386 35553.49788547032 33910.82427820984 37323.5631485179 1.332232760629695 0.8953444303388722 1.0643751837640247 0.9841600233896374 1.0878036346908468 0.9789664284075177 1.0754585520784554 0.9525751264421317 0.9085634226097843 1.0 15.18779910130489 -4.750180546879898 24.999813252947312 0.9995337326761495 1.3322334834571044 0.7207560270919247 0.06305260348412826 264.8132716070828 587970.4771734033 0.015269247106829626 0.23096436169973994 1.7775402892698413e-05 4.750180546879898 0.3326997507809548 SRS(ph)PPTSELMMK ddPTM_PC-9_AZD4547_30min_R2 1 SRSPPTSELMMK 12 1 Q9HC77;F6VUX8;Q9HC77-2 Q9HC77 CENPJ Centromere protein J 1 S(0.099)RS(0.897)PPT(0.003)SELMMK 58.83 0.032532 9121500.0 35814.0 24929.0 34894.0 61815.0 43790.0 39551.0 38537.0 39755.0 38845.0 45984.0 True False 47202.10702252307 32986.81173683503 34431.28276066542 47564.506782229735 37710.51437042079 37077.86971766017 41966.718343938854 33611.77822901814 40898.267396360745 44374.11415644027 1.0637306889352822 0.7433796113774919 0.775931720896522 1.0718976071171085 0.8498313732522735 0.8355743077358727 0.945747743740547 0.7574636444689425 0.9216694952416293 1.0 15.437430698719101 -8.533095170276841 22.937936274849353 1.0000000141256626 0.8760051759342912 0.09764034748598704 0.11065929382585464 1078.2210182440326 2420827.444048449 0.10333522991573625 0.026681041710521332 2.9302510465281813e-09 8.533095170276841 -0.12399483819137147 SRS(ph)PQWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRSPQWR 7 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.186)RS(0.814)PQWR 59.35 0.037485000000000004 13251000.0 3911.5 3737.0 3579.5 4830.7 4233.9 5064.7 3740.9 4373.7 4042.3 2526.9 True False 4573.6396943535 4107.9846630273905 3664.848855329346 4560.051540340709 3404.297688305459 4799.098216105211 3386.5348702293945 4258.8950093182075 4101.410990219729 2985.006967070607 1.5322040265929187 1.3762060552437634 1.2277521948050643 1.5276518918198043 1.1404655754108108 1.607734343352269 1.134514896477054 1.4267621671576045 1.3740038249373756 1.0 11.543518583437422 -12.727522417823762 0.35224872171138705 4.7471907191591685e-17 1.3807527236053794 0.34451301165940806 0.15442180259422897 119.7505775805877 3.224736961782903 88.77624799406316 0.10948130059157524 1.872740411634833e-13 12.727522417823762 1.3807527236053794 SRS(ph)PVDLR ddPTM_PC-9_AZD4547_30min_R2 1 SRSPVDLR 8 1 Q13523 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 S(0.074)RS(0.926)PVDLR 64.10300000000001 0.02615 11946000.0 14049.0 9524.9 15671.0 18726.0 19868.0 13286.0 12697.0 16320.0 12110.0 14240.0 True False 18516.289762646633 12603.637655428616 15463.192300750496 14409.010013815972 17109.671146643523 12455.224319709565 13827.00840265177 13798.118996291703 12750.109876945004 13741.46193431867 1.3474759709811552 0.9171977272630367 1.1252945556056073 1.0485791164497666 1.24511287288239 0.9063973236066837 1.006225427013661 1.0041230738216824 0.927856871262161 1.0 13.746247878115526 -6.776735823969491 24.97862370368632 0.9715097874676487 1.1190029215486983 0.3585947785823391 0.11092964425758961 296.3458438170501 483920.73396487156 0.03718232307602013 0.03291224130886937 1.6721074275531886e-07 6.776735823969491 0.14749313408104958 SRS(ph)PVDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRSPVDLR 8 1 Q13523 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 S(0.315)RS(0.685)PVDLR 81.525 0.0083801 8386000.0 12825.0 12817.0 15551.0 19452.0 20253.0 19403.0 16203.0 18396.0 16565.0 12676.0 True False 14996.01919470372 14089.387055397923 15921.79481749592 18362.167504234898 16284.570037376996 18385.47252297064 14668.13454043864 17913.124492173152 16807.231787098874 14974.058456839204 1.0014665855571363 0.9409197310140579 1.0632918833186369 1.2262652478058291 1.0875187968789606 1.227821607346091 0.9795697394074993 1.1962771845592448 1.1224232786016934 1.0 13.87017767122103 -5.484749995859601 5.6185110590445 1.1269680805357967 0.9762034758682634 0.34210954760580425 0.08138983702462219 0.1916665776977242 16.14193414350062 0.020292479519070372 0.04145811970799922 3.2752918469809434e-06 5.484749995859601 -0.15076460466753328 SRS(ph)QPCDLDAR ddPTM_PC-9_AZD4547_30min_R2 1 SRSQPCDLDAR 11 1 Q9NYF3 Q9NYF3 FAM53C Protein FAM53C 1 S(0.125)RS(0.875)QPCDLDAR 74.133 0.010935 21455000.0 18606.0 17586.0 23694.0 31321.0 24521.0 25113.0 22101.0 26122.0 22724.0 26857.0 True False 24522.320971158315 23270.3305870264 23379.802078615437 24100.427354626187 21116.68241326988 23542.680140062173 24067.94618468985 22085.44512384385 23925.144248034532 25916.744604634576 0.9461960344654203 0.8978878690985391 0.9021118367788573 0.9299172300488856 0.8147891540935923 0.9083965019222414 0.9286639410871798 0.8521689533451052 0.9231539150853115 1.0 14.661596892613684 -8.543598919681223 22.427927013768464 1.0000000016209354 0.8967963722488552 0.4146087384767203 0.0366519558507181 1145.9687225985253 1240419.1409268237 0.0347273751419158 0.008966569679459122 2.860230808843682e-09 8.543598919681223 -0.10320362937208016 SRS(ph)QPCDLDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRSQPCDLDAR 11 1 Q9NYF3 Q9NYF3 FAM53C Protein FAM53C 1 S(0.095)RS(0.905)QPCDLDAR;S(0.402)RS(0.598)QPCDLDAR 104.55 0.012881 9545100.0 14629.3 11058.9 17634.1 19028.2 20416.9 14847.1 17615.0 18944.9 15917.2 12420.0 True False 17105.75154815431 12156.754506276058 18054.563821696673 17962.111644256755 16416.355008942977 14068.491939174231 15946.379678443915 18447.616448780787 16149.958937616075 14671.647683334098 1.1659052832617547 0.8285882246262789 1.2305750663714012 1.2242736488731514 1.1189169317084091 0.9588897063793995 1.086884038018294 1.257365010866224 1.1007597296628946 1.0 13.840743279946642 -5.280747376797015 24.997851333526857 1.127832912507585 0.9972466848327893 0.1493165338718767 0.11870091828227064 1288.2628850780363 1667898.1563196604 0.031109252331179487 0.06491193774037135 5.239050964495815e-06 5.280747376797015 -0.13058622767479566 SRS(ph)QPCDLDAR ddPTM_PC-9_Lapatinib_30min_R1 1 SRSQPCDLDAR 11 1 Q9NYF3 Q9NYF3 FAM53C Protein FAM53C 1 S(0.245)RS(0.755)QPCDLDAR 76.868 0.0095008 25554000.0 22772.0 20547.0 24445.0 27065.0 25510.0 23900.0 26310.0 25552.0 23184.0 19158.0 True False 22447.26710412666 20499.424683903915 22435.226460428796 29055.450386193264 24009.55195458968 22877.85271362115 27672.203064181307 26739.239202162113 20572.77378165687 22469.434773569614 0.9990134300365655 0.9123248933710169 0.998477562364806 1.2931099815813196 1.0685427647175032 1.0181766005316675 1.2315486946174372 1.1900272290611864 0.9155892878024795 1.0 14.455676213029243 -5.540026829540873 24.990898736088553 1.1134948835003946 0.9556021087871126 0.238335549942848 0.10907196125620729 283.96888612746193 413842.691651508 0.029147195352438145 0.05049841097199557 2.883853340947973e-06 5.540026829540873 -0.157892774713282 SRS(ph)SDIVSSVR ddPTM_PC-9_AZD4547_30min_R2 3 SRSSDIVSSVR 11 1 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 S(0.127)RS(0.752)S(0.121)DIVSSVR;S(0.027)RS(0.487)S(0.487)DIVSSVR;S(0.315)RS(0.654)S(0.031)DIVSSVR 80.37100000000001 0.0076637 186583000.0 131426.0 132754.0 216531.0 315471.0 249366.0 147149.0 174342.0 329998.0 207371.0 192470.0 True False 173216.7341693788 175664.13435403723 213659.65746115797 242744.0349283637 214745.83527048113 137947.74976824818 189858.1002547936 279004.3916996494 218332.2077037128 185731.6838833081 0.9326181217320345 0.9457951959580783 1.15036730941069 1.3069608257085281 1.1562154112886958 0.7427259952853186 1.0222170837264257 1.5021906110265109 1.1755248385132124 1.0 17.502860419393848 SRS(ph)SDIVSSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRSSDIVSSVR 11 1 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 SRS(0.873)S(0.127)DIVSSVR;S(0.142)RS(0.429)S(0.429)DIVSSVR 111.66 0.00084186 44266000.0 50924.0 52562.0 49142.0 54963.0 62651.0 62140.0 47598.0 57423.0 50831.0 47927.0 True False 59544.427405153416 57780.00798984367 50313.731652072835 51883.60130245026 50374.9862939666 58881.26900878197 43089.17286032204 55915.7070946977 51574.30721219578 56615.78571007678 1.0517283591200852 1.0205635630622305 0.8886873337716079 0.9164158132175447 0.8897692695095917 1.0400150465155864 0.7610805417587413 0.9876345685819127 0.9109527769569806 1.0 15.788916743391264 -5.148324861589855 4.775839869913366 0.9208541299035711 1.0439567837886614 0.27675768585424265 0.07264498610467872 0.26028517240147087 9.024041364110166 0.017536702117075035 0.050512193016574565 7.106817096118931e-06 5.148324861589855 0.12310265388509034 SRS(ph)SDIVSSVR ddPTM_PC-9_Lapatinib_30min_R1 3 SRSSDIVSSVR 11 1 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 S(0.081)RS(0.555)S(0.364)DIVSSVR;S(0.228)RS(0.747)S(0.025)DIVSSVR;S(0.026)RS(0.487)S(0.487)DIVSSVR 95.195 0.0029816999999999995 117621000.0 128468.0 93069.0 138500.0 94368.8 129144.0 109852.5 98497.0 103121.0 131339.0 111959.0 True False 126636.02276185395 92853.50444864228 127113.06462546044 101308.99635708837 121548.00382687307 105154.36465368497 103596.69271047758 107912.37812171862 116546.21875901624 131310.96397400965 0.9643979369987642 0.7071268204764741 0.968030854229506 0.7715197062839356 0.9256500763403964 0.8008041481935824 0.7889416814500155 0.8218078281953493 0.8875589305862092 1.0 17.002627855332925 -8.623738002235578 3.6534943299016818 0.9999428038159793 0.8405764263052831 0.25243674693380547 0.08125638868246352 0.5884021157105783 17.642877991186044 0.07114934089313338 0.01871241544472801 2.378274600764468e-09 8.623738002235578 -0.15936637751069627 SRS(ph)SPATADKR ddPTM_PC-9_AZD4547_30min_R2 1 SRSSPATADKR 11 2 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 S(0.193)RS(0.684)S(0.122)PATADKR 56.956 0.025057 1955200.0 4543.5 4233.2 3907.5 5870.7 5601.2 5324.2 4301.5 4583.7 7073.6 5114.4 True False 5988.238489329134 5601.499115262147 3855.6839968848567 4517.300816410839 4823.570063749734 4991.276932334615 4684.325166890337 3875.3944879474434 7447.49605495939 4935.346412702206 1.2133370160029855 1.1349758754209125 0.7812387772743572 0.9152955919739626 0.9773518736871659 1.0113326431329033 0.9491380695859949 0.7852325174122039 1.5090118164333126 1.0 12.268935635878263 -8.252657729967908 24.9988437962953 1.2545059249939676 0.9691013353583485 0.3064862964255324 0.17057469016987048 678.012566380749 1930121.6242285196 0.1170740240034897 0.04272406822535958 5.589105018590998e-09 8.252657729967908 -0.2854045896356191 SRS(ph)TCGDSEVEEESPGKR ddPTM_PC-9_AZD4547_30min_R2 1 SRSTCGDSEVEEESPGKR 18 2 O95696-2;O95696 O95696-2 BRD1 Bromodomain-containing protein 1 1 S(0.203)RS(0.773)T(0.019)CGDS(0.005)EVEEESPGKR 83.87100000000001 0.012554000000000001 0.0 5525.5 2890.3 6722.7 10880.0 6402.6 5960.4 4130.5 8074.2 3960.2 5272.1 True False 7282.4940624602505 3824.532952102943 6633.552605465849 8371.784094324352 5513.70950692067 5587.69524576222 4498.10649816123 6826.51791665799 4169.528087091462 5087.525383702352 1.431441322295782 0.7517471980296461 1.30388589838119 1.645551316784181 1.0837704170643705 1.0983129958746032 0.8841442860552012 1.3418150086339458 0.819559171232511 1.0 12.312748372242474 -6.495633488073246 24.952487944927174 1.0466408530488673 1.2614269973882477 0.19080345699828516 0.2465718973686859 1449.8019911388537 1327797.960453359 0.07767418810064292 0.08783683253926731 3.1942324102037674e-07 6.495633488073246 0.21478614433938037 SRS(ph)TCGDSEVEEESPGKR ddPTM_PC-9_Lapatinib_30min_R1 1 SRSTCGDSEVEEESPGKR 18 2 O95696-2;O95696 O95696-2 BRD1 Bromodomain-containing protein 1 1 S(0.165)RS(0.669)T(0.165)CGDS(0.002)EVEEESPGKR 81.14399999999999 0.009157700000000001 3879400.0 3690.5 2655.6 4146.3 3087.7 3068.8 4977.2 2633.9 2855.6 3362.0 2879.9 True False 3637.8727932451884 2649.4511213595774 3805.407219180848 3314.7797582652515 2888.2992174929377 4764.336758419884 2770.270454228321 2988.281600880328 2983.3361565704963 3377.686877774464 1.077030797964955 0.7843980858004469 1.1266311404472775 0.9813756805217357 0.8551115961927233 1.4105323941569963 0.8201679298507487 0.8847124404998984 0.8832482892956014 1.0 11.72181987662016 SRS(ph)TQMESTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRSTQMESTR 10 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.001)RS(0.991)T(0.007)QMESTR 81.625 0.034792000000000003 359500.0 3629.9 4253.9 5467.9 5740.6 6394.6 5828.2 3177.6 6335.4 4962.1 4756.3 True False 4244.370376207021 4676.199078954299 5598.275473126227 5418.972793276308 5141.624034020188 5522.558932040278 2876.5947241682293 6169.102462911163 5034.661325129089 5618.579539149917 0.7554169780159752 0.8322742512357137 0.996386263488447 0.9644738061492658 0.9151110166179314 0.9829101632466759 0.5119789982724805 1.097982580815175 0.8960736944360899 1.0 12.45598972634527 -14.522878745279787 0.2105699796739915 1.5550275778153753 0.8708390791130368 0.054786804480457696 0.15235938869018978 542.3113629148679 5.3926627809209045 126.65560471785784 0.3240107112182599 3.000000000003805e-15 14.522878745279787 -0.6841884987023384 SRS(ph)TTAHSWQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRSTTAHSWQR 11 1 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 S(0.015)RS(0.816)T(0.139)T(0.026)AHS(0.003)WQR 53.3 0.044826 1887300.0 4741.0 4508.1 4539.5 5227.8 5066.1 5401.4 5534.0 4675.1 4859.9 3090.3 True False 5543.557660981703 4955.634375005024 4647.738896149618 4934.903314756282 4073.434072303144 5118.141075378738 5009.7794573096 4552.383578677906 4930.9668434724945 3650.5469271986585 1.5185553758202732 1.3575046352870357 1.2731623476803737 1.3518257436956735 1.115842133668721 1.4020203485800073 1.3723366819322012 1.247041517192958 1.3507474199917762 1.0 11.83389691031128 -13.415758576982599 0.24229705152631678 4.4478587472002284e-20 1.360389011645647 0.5087297327088319 0.09897491992452943 84.03571606844216 1.3615976894414132 41.808868320661595 0.15807407361306347 3.839206065125335e-14 13.415758576982599 1.360389011645647 SRS(ph)TTELDDYSTNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRSTTELDDYSTNK 14 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.132)RS(0.819)T(0.037)T(0.011)ELDDYSTNK;S(0.219)RS(0.668)T(0.057)T(0.057)ELDDYSTNK 117.07 0.00065362 33646000.0 32194.4 35374.0 54870.0 65663.0 86969.0 72234.0 68440.0 60424.0 65834.0 55840.0 True False 37644.27605161557 38885.69694137834 56178.3088956338 61984.11499231822 69928.04876219024 68445.92187931054 61956.867737309214 58837.93402452008 66796.69770430848 65963.3499708033 0.5706847221718981 0.589504580325134 0.851659427856521 0.9396750622846417 1.0601045700853853 1.0376356250797765 0.9392619957102324 0.8919791679859032 1.0126334962350159 1.0 16.009377047935814 -5.385098034587917 2.055549344371046 0.9839076565942887 0.5547080648619687 0.9206241990080921 0.046847564078790094 0.09497459033103041 0.7548152254791001 0.014919561072191008 0.0465724694274677 4.1200450559449356e-06 5.385098034587917 -0.42919959173232003 SRS(ph)TTELDDYSTNK ddPTM_PC-9_Lapatinib_30min_R1 1 SRSTTELDDYSTNK 14 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.07)RS(0.747)T(0.176)T(0.006)ELDDYSTNK 121.26 3.5258e-05 34625000.0 26225.0 42516.0 56619.0 42762.0 59313.0 47375.0 52488.0 44818.0 58586.0 41371.0 True False 25851.026690923987 42417.556814175245 51964.00437566039 45906.86012985025 55824.32595384465 45348.88168651894 55205.571814243536 46900.407896153025 51987.42774206994 48521.922226607625 0.5327700450570411 0.8741936606731344 1.0709387013353988 0.9461055544225044 1.1504969999567054 0.9346060420840312 1.137744946633026 0.9665818200094839 1.0714214391440982 1.0 15.566349084415597 -4.78208550271194 2.2043802283616425 1.0352160397091836 0.39916270750593436 0.819024255149108 0.07172380427768188 0.2306247229396698 1.3047977664837564 0.017137029591594948 0.2927861675034908 1.651636596513625e-05 4.78208550271194 -0.6360533322032493 SRS(ph)WEDSPER ddPTM_PC-9_AZD4547_30min_R2 1 SRSWEDSPER 10 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IU26;B1AN86 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(0.299)RS(0.701)WEDSPER 82.774 0.006819499999999999 69941000.0 35330.0 20973.0 29835.0 39834.0 37066.0 28021.0 27890.0 42034.0 32860.0 33616.0 True False 46564.205090348456 27752.11210063144 29439.36840615729 30650.886729165093 31920.02570573231 26268.842440356893 30372.15596991083 35538.61114522828 34596.91251498043 32439.11407191407 1.435433932847875 0.8555138725153824 0.907526893024678 0.9448743470988552 0.9839980720487311 0.8097891447380979 0.936281918876668 1.095548141864878 1.066518414722509 1.0 14.985446798934811 -4.754369629871319 24.995715378295298 0.9524428351453121 1.4354347698070278 0.7506062824830184 0.08296448017929314 131.6033014144563 465254.61810739903 0.022323273838563133 0.21954216640020696 1.760477059130202e-05 4.754369629871319 0.48299193466171564 SRS(ph)WEDSPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRSWEDSPER 10 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IU26;B1AN86 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(0.062)RS(0.936)WEDS(0.002)PER;S(0.077)RS(0.846)WEDS(0.077)PER 110.15 0.0085961 21369000.0 44420.0 41856.0 47969.0 51419.0 65745.0 46043.0 54488.0 49878.0 56934.0 49124.0 True False 51939.428665008905 46011.187063332756 49112.762883445575 48538.16013264722 52862.739204431455 43628.42402593092 49326.50218104182 48568.75535010944 57766.55204145415 58029.792334629994 0.8950476397623331 0.7928890525406036 0.8463370435695481 0.8364351857878608 0.9109586141476671 0.7518280226533763 0.8500203119218406 0.8369624187182457 0.9954637043734732 1.0 15.824506145622596 -8.264083114062311 8.678561562410053 0.9982034462624008 0.8382783529525771 0.685281929989177 0.04272746848356563 0.06003246730222345 64.39391838214566 0.03287902253469985 0.010313984617104798 5.4439845741947226e-09 8.264083114062311 -0.15992509330982363 SRS(ph)WEDSPER ddPTM_PC-9_Lapatinib_30min_R1 4 SRSWEDSPER 10 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IU26;B1AN86 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(0.002)RS(0.996)WEDS(0.002)PER;S(0.124)RS(0.876)WEDSPER;S(0.064)RS(0.807)WEDS(0.129)PER;S(0.029)RS(0.971)WEDSPER 123.26 0.0022703000000000003 107764200.0 132381.0 102050.0 124763.0 100547.0 109320.0 113256.0 96003.0 97962.0 115146.0 104931.0 True False 130493.22266429805 101813.70949493333 114505.46773910709 107941.56179495917 102890.01253138951 108412.30489263088 100973.56559371333 102513.67214786328 102177.04493886566 123068.18353823095 1.0603327270509402 0.8272951348412894 0.9304229935557319 0.8770874704706053 0.8360407180254422 0.8809125297518734 0.8204684808917004 0.8329827352657526 0.8302474449630964 1.0 16.90909830868415 -4.754617593862424 24.998497099455793 0.8651339799570169 1.0603330600917096 0.5224378991291106 0.05419163572820933 176.16570387625805 645503.2606476609 0.012719016361871427 0.12207403119756743 1.7594721872330532e-05 4.754617593862424 0.19519908013469267 SRS(ph)WTSPK ddPTM_PC-9_Lapatinib_30min_R1 1 SRSWTSPK 8 1 O75494-2;O75494 O75494-2 SRSF10 Serine/arginine-rich splicing factor 10 1 S(0.167)RS(0.813)WT(0.004)S(0.017)PK 53.6 0.045821 3125500.0 22332.0 14715.0 12032.0 16154.0 16532.0 15639.0 13688.0 16713.0 17412.0 12706.0 True False 22013.54158481276 14680.928321586902 11042.77540486313 17342.019048164275 15559.62026316255 14970.156426289588 14396.697664101623 17489.546993806183 15450.877203511442 14902.215170319225 1.4771992843491604 0.985150741268784 0.7410156999247367 1.1637208864561568 1.0441145886923362 1.0045591380337657 0.9660776937898171 1.1736206190768306 1.0368174816241407 1.0 13.863239178538782 -4.75929661609903 24.99870760435415 1.0136980767803683 1.4771998789205236 0.604016846807995 0.11280569438821576 40.394608170198666 471153.4100381828 0.02880845055080002 0.18506254351298101 1.7406176536556172e-05 4.75929661609903 0.46350180214015535 SRSEPSPDAPESPS(ph)SCSPSK ddPTM_PC-9_AZD4547_30min_R2 1 SRSEPSPDAPESPSSCSPSK 20 1 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 SRSEPSPDAPES(0.031)PS(0.823)S(0.071)CS(0.046)PS(0.03)K 101.42 0.0001281 6981600.0 25831.0 20823.0 23675.0 41154.0 32317.0 33012.0 28160.0 34177.0 24867.0 31996.0 True False 34044.720681822575 27553.627534041298 23361.05403102981 31666.581122961798 27830.342382025316 30947.75442136473 30666.185446851545 28895.729959329747 26181.418853013343 30875.82977882446 1.1026333842911464 0.8924011996250341 0.756612994642544 1.0256106912689245 0.9013633829887278 1.0023294804724439 0.9932100826609461 0.9358689358738231 0.8479583881813378 1.0 14.914190288771747 -4.754325576471631 24.834617140604013 0.9275331552108051 1.1026337163600486 0.3048271706525223 0.0789386133949838 299.7272286724288 1046262.8992213014 0.01996534459062622 0.19580039217068823 1.760655645173438e-05 4.754325576471631 0.17510056114924344 SRSEPSPDAPESPSS(ph)CSPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRSEPSPDAPESPSSCSPSK 20 1 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 SRSEPSPDAPES(0.001)PS(0.04)S(0.749)CS(0.105)PS(0.105)K 99.72200000000001 0.00016326 3150500.0 9817.3 4833.7 11790.0 13740.0 12704.0 15855.0 13762.0 11559.0 11337.0 11323.0 True False 11479.174989486532 5313.55779118959 12071.118313824 12970.192345681035 10214.742396427057 15023.535888867682 12458.363731748224 11255.588497772862 11502.782177503179 13375.770267181324 0.8582066497995811 0.39725247107651734 0.9024615459673072 0.9696781633207763 0.7636750775758957 1.1231903351188157 0.9314128071050951 0.8414908654187548 0.8599715715607278 1.0 13.707334353578755 -5.392621406429484 8.900454285527823 0.9229971312326742 0.628506287059923 0.4249289823869229 0.13803699823748397 0.26371686925774473 17.619208686312536 0.034150724150333676 0.0712462341231218 4.0492873203874524e-06 5.392621406429484 -0.2944908441727513 SRSEPSPDAPESPSS(ph)CSPSK ddPTM_PC-9_Lapatinib_30min_R1 1 SRSEPSPDAPESPSSCSPSK 20 1 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 SRSEPSPDAPES(0.001)PS(0.027)S(0.939)CS(0.017)PS(0.017)K 119.2 6.3849000000000005e-06 5159800.0 21654.0 15665.0 20865.0 19781.0 22961.0 16777.0 15366.0 16262.0 17949.0 16564.0 True False 21345.209989142753 15628.728654954724 19149.560241229145 21235.760727481585 21610.47912306285 16059.48681909715 16161.576293584561 17017.59188734972 15927.39460865076 19427.065329857367 1.098735687903278 0.8044822205304989 0.9857155425219204 1.0931018332884506 1.1123903047698 0.8266553154796571 0.8319103281516179 0.8759733700589076 0.8198559246193516 1.0 14.245780362107872 -6.778944325784898 24.999416154899425 0.8606917550008438 1.0092542581911645 0.37030481025231066 0.09563201174029522 281.19440442680593 401580.91527127824 0.034756420328692146 0.030722052491951455 1.6636259045877876e-07 6.778944325784898 0.14856250319032072 SRSEPSPDAPESPSSCS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 1 SRSEPSPDAPESPSSCSPSK 20 1 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 SRSEPSPDAPES(0.001)PS(0.002)S(0.029)CS(0.484)PS(0.484)K 142.85 1.3429e-10 0.0 15025.0 10004.0 11885.0 24626.0 22403.0 16696.0 16634.0 19143.0 13532.0 18896.0 True False 19802.637460585498 13237.597361117483 11727.397134478952 18948.856167907285 19292.730153928675 15651.996480646598 18114.393775672186 16184.889212378179 14247.273893874473 18234.45679149477 1.086000953415963 0.7259660933410417 0.6431448585816413 1.0391785389924935 1.0580370106186834 0.8583747056258497 0.9934155967904356 0.8875991973573578 0.7813379941496219 1.0 14.154379601658922 -5.781667884595321 24.999973110859866 0.9438022946838325 0.8091300168801242 0.1605945261720828 0.13256775672656804 413.44615059917555 510967.63279620605 0.038135637673002126 0.05664115779050857 1.653225576189178e-06 5.781667884595321 -0.13467227780370827 SRSEPSPDAPESPSSCSPS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRSEPSPDAPESPSSCSPSK 20 1 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 SRSEPSPDAPESPS(0.001)S(0.009)CS(0.146)PS(0.843)K 94.955 0.00063827 0.0 9597.1 9011.7 8576.7 13641.0 17614.0 10757.0 12963.0 13950.0 14649.0 12932.0 True False 11221.699478634779 9906.32201974951 8781.201055315885 12876.738994718704 14162.66314315697 10192.883983383763 11735.05079600728 13583.827281246768 14863.213911814766 15276.469230344326 0.7345741551552122 0.6484693465733656 0.574818757064191 0.8429132936779048 0.9270900840768261 0.6672277363107691 0.7681782104923452 0.8891994004913525 0.9729482439758598 1.0 13.899023518964883 -7.402690574397665 0.31540562300434133 1.0325910529741869 0.6265676258991598 0.5411009493309022 0.09396055395052812 1.409541359057678 0.40108548049325204 0.15290281301780556 0.20624285573163698 3.956484107680072e-08 7.402690574397665 -0.40602342707502703 SRSEYLNR ddPTM_PC-9_AZD4547_30min_R2 2 SRSEYLNR 8 1 P46087-2;P46087;P46087-4;P46087-3;F5GYR3 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 0 ; 119.21 0.0044971 2609100.0 15678.7 10711.2 11183.0 16181.7 11543.1 11096.6 8605.5 9322.400000000001 9403.6 10213.599999999999 False True 20664.20046278084 14173.385931067729 11034.706113157605 12451.259069772814 9940.53981340955 10402.727847816432 9371.372828937534 7881.837287440544 9900.655098170115 9856.024972777894 2.0966059359483027 1.4380428185007934 1.1195899100940998 1.263314480651469 1.0085749418112357 1.0554689011592928 0.9508268145445088 0.7996973738611652 1.0045282074178472 1.0 13.266790196139015 -1.5228787453601875 0.6317919383948212 0.956695895327449 89.34071476982774 0.931804804377135 0.0912943670696847 47.53091032918477 0.32844378680809455 0.04087239400202768 5850.130847944414 0.02999999999448416 1.5228787453601875 88.3840188745003 up SRSEYLNR ddPTM_PC-9_Lapatinib_30min_R1 3 SRSEYLNR 8 1 P46087-2;P46087;P46087-4;P46087-3;F5GYR3 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 0 ;; 136.75 3.1744e-05 1395900.0 32157.7 21603.699999999997 19380.5 19006.4 14553.800000000001 14829.7 15121.7 15449.7 17509.4 13288.8 False True 31699.12530100006 21553.677959977373 17787.11010089344 20404.194059491736 13697.774097871705 14195.468300719156 15904.627634953651 16167.549463902793 15537.306989843979 15585.75137378703 2.0338528788745713 1.3829091355985268 1.1412417453808978 1.3091569068533087 0.8788651743097462 0.9107978152785031 1.0204594731122765 1.03732884454286 0.9968917517814041 1.0 13.927940087102183 -1.5228788618294258 0.7175496941781273 0.989419259082807 148.57877261363558 0.9106617484529774 0.09742907136832799 86.09617326050964 0.4253945455419009 0.03894284717460939 20445.025634510614 0.029999991949075287 1.5228788618294258 147.58935335455277 up SRSGSS(ph)PGLR ddPTM_PC-9_Lapatinib_30min_R1 1 SRSGSSPGLR 10 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.001)RS(0.002)GS(0.363)S(0.635)PGLR 63.966 0.024941 3478200.0 12216.0 2219.4 4791.5 4090.5 2808.1 3236.1 841.61 920.27 2200.7 894.15 True False 12041.797599859967 2214.261115659531 4397.561365724874 4391.329015507986 2642.933078937016 3097.6995467175507 885.1844477706438 963.029103810807 1952.8339916016323 1048.7026361200165 11.482566349229497 2.111428959358623 4.193334901869747 4.187391987260562 2.5201930346197314 2.953839763556236 0.8440757344194765 0.9183052188881837 1.8621427317344366 1.0 10.034389938542613 -3.6889957534583377 1.5711402018061607 2.2456043565736254 199.99999997514556 0.8233845496898378 1.2583582753984854 13.39727821302003 1.8750374456061796 0.3779445950495977 8487.671349852542 0.00020464646470063117 3.6889957534583377 197.75439561857192 SRSLSNS(ph)NPDISGTPTSPDDEVR ddPTM_PC-9_Lapatinib_30min_R1 2 SRSLSNSNPDISGTPTSPDDEVR 23 1 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 S(0.045)RS(0.143)LS(0.143)NS(0.67)NPDISGTPTSPDDEVR;S(0.05)RS(0.074)LS(0.203)NS(0.661)NPDIS(0.011)GTPTSPDDEVR 88.413 1.2025e-05 2795000.0 17333.1 11630.7 23985.8 10189.2 13491.5 17012.2 13249.8 14168.4 18536.5 8557.2 True False 17085.92681549875 11603.769828738079 22013.780111865522 10938.54775817478 12697.956495309552 16284.627863375143 13935.809812230687 14826.715588287172 16448.724172001486 10036.300618247733 1.7024128177700832 1.1561799780728386 2.19341577631111 1.089898377325068 1.2652028848381114 1.6225727469508904 1.3885404933858767 1.4773088364182352 1.638923025292293 1.0 13.292939969235379 -10.81485337093241 4.24201816139042 0.999510399730008 1.4940142324292651 0.19983299546297528 0.30188049958917174 207844373.13140294 795.0417109668558 994967.6592660771 0.06945656249423446 1.531604483747382e-11 10.81485337093241 0.49450383269925713 SRSPGS(ph)PVGEGTGSPPK ddPTM_PC-9_AZD4547_30min_R2 1 SRSPGSPVGEGTGSPPK 17 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5;A0A0A0MSR2 P35611 ADD1 Alpha-adducin 1 S(0.296)RS(0.248)PGS(0.356)PVGEGT(0.005)GS(0.096)PPK 118.84 0.00051689 11795000.0 13507.0 10188.0 12531.0 23958.0 21106.0 16001.0 15273.0 18906.0 14235.0 16484.0 True False 17801.94503694699 13481.071762801364 12364.830752390055 18434.853247410185 18175.796216079038 15000.454940514268 16632.267412278525 15984.512116659971 14987.433038671525 15906.900177339117 1.1191335105193871 0.8474983568455673 0.7773249730959477 1.158921791291076 1.1426359638549928 0.943015595325344 1.0456007912825631 1.0048791366297387 0.9421969630527096 1.0 13.957365100542265 -5.7633554375437335 24.999996986416864 1.0353284114789545 0.9079369084660174 0.21026571275316164 0.10563262057895828 77.03089185536759 1005093.9746922334 0.030260501737706023 0.04757792433754481 1.7244260006286126e-06 5.7633554375437335 -0.1273915030129371 SRSPGS(ph)PVGEGTGSPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRSPGSPVGEGTGSPPK 17 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5;A0A0A0MSR2 P35611 ADD1 Alpha-adducin 1 S(0.367)RS(0.105)PGS(0.518)PVGEGT(0.002)GS(0.007)PPK 116.69 0.00065766 5161800.0 16762.0 5425.9 9952.6 22489.0 20230.0 21957.0 21954.0 16415.0 21207.0 14843.0 True False 19599.475535409263 5964.547493476132 10189.907729445691 21229.01424032174 16266.076722270107 20805.53626691061 19874.35818680429 15984.123643130157 21517.112255297674 17533.918402876654 1.1178035100353683 0.3401719659250596 0.581154052124134 1.210739878704971 0.927692050831117 1.1865879485042663 1.133480704663463 0.9116116133235663 1.2271707761436559 1.0 14.097860818812375 -5.7562280206687495 24.997359060511496 1.081300895569723 0.6457559641509558 0.44225267491493325 0.20765947602370724 106.21991183002565 509498.1741686965 0.054234797971848214 0.09045952522788182 1.752959891395837e-06 5.7562280206687495 -0.43554493141876716 SRSPGS(ph)PVGEGTGSPPK ddPTM_PC-9_Lapatinib_30min_R1 1 SRSPGSPVGEGTGSPPK 17 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5;A0A0A0MSR2 P35611 ADD1 Alpha-adducin 1 S(0.04)RS(0.003)PGS(0.955)PVGEGTGS(0.002)PPK 220.89 3.2839e-22 11905000.0 31365.0 25993.0 31162.0 29661.0 29189.0 30827.0 25900.0 20412.0 26764.0 25308.0 True False 30917.72934836346 25932.814805505157 28599.980648798613 31842.368886195414 27472.160407781976 29508.601071246823 27240.975270326704 21360.416037669587 23749.556482585594 29682.45407920974 1.041616345665264 0.8736748900984264 0.9635315386146149 1.0727673931953803 0.9255353460489002 0.9941429031609389 0.9177467333944904 0.7196310648933474 0.8001210553281145 1.0 14.857322755252842 -7.5496316868762765 9.093374377243292 0.8193232891233155 0.9734324048231567 0.3461983030481638 0.08381116496445647 0.2700073178746244 83.79881590670952 0.03776692111657458 0.02192483730825746 2.8207741375970936e-08 7.5496316868762765 0.1541091156998412 SRSPGSPVGEGTGS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRSPGSPVGEGTGSPPK 17 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5;A0A0A0MSR2 P35611 ADD1 Alpha-adducin 1 S(0.077)RS(0.042)PGS(0.022)PVGEGT(0.005)GS(0.853)PPK 118.05 0.00056904 5076600.0 16590.0 4671.8 9564.4 24131.0 26454.0 25315.0 24345.0 16916.0 22609.0 18813.0 True False 19398.359332564112 5135.585429149413 9792.451569188992 22779.018303757555 21270.528601627953 23987.43683548946 22038.865357463343 16471.972923983532 22939.61385297425 22223.647976373937 0.8728701675434473 0.23108651804641064 0.44063205012963635 1.0249900613964924 0.9571123797605483 1.0793654066600864 0.9916853156103338 0.7411912275381145 1.0322163974772036 1.0 14.439808031805283 -5.76068799968043 24.99999899484661 0.9687098937467717 0.48648518270991054 0.6044433130039742 0.17013988750782533 12.454201864303677 414345.5844650547 0.046051137753823086 0.07410912462957477 1.7350500226997378e-06 5.76068799968043 -0.4822247110368612 SRSPGSPVGEGTGS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 1 SRSPGSPVGEGTGSPPK 17 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5;A0A0A0MSR2 P35611 ADD1 Alpha-adducin 1 S(0.187)RS(0.063)PGS(0.184)PVGEGT(0.014)GS(0.552)PPK 93.34200000000001 0.022964 0.0 6979.3 7783.5 8773.1 7156.8 7876.9 6769.4 7073.4 8401.1 7782.7 5081.3 True False 6879.7739021531315 7765.477783966816 8051.809583145341 7683.134946384924 7413.5962285812375 6479.8885422421345 7439.626041587991 8791.445775723394 6906.1303705357495 5959.595934593345 1.1544027443569587 1.3030208539627604 1.3510663594502164 1.2892040048868154 1.2439763215401796 1.0873033362259805 1.2483440359443825 1.4751748058441618 1.1588252704261555 1.0 12.540998802779065 -6.515567932948292 24.73460964166113 1.2202078417490787 1.280021850307834 0.06543253660079829 0.12536485456995444 1129.0202750485105 3819819.350759384 0.04141013026466036 0.04306895254273541 3.050928761284546e-07 6.515567932948292 0.059814008558755294 SRSSS(ph)MT(ph)RSPPRVSK ddPTM_PC-9_Lapatinib_30min_R1 1 SRSSSMTRSPPRVSK 15 3 Q9BRL6-2;Q9BRL6 Q9BRL6-2 SRSF8 Serine/arginine-rich splicing factor 8 2 S(0.002)RS(0.35)S(0.417)S(0.448)MT(0.464)RS(0.318)PPRVSK 67.648 0.014533 6529700.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SRSSSMT(ph)RS(ph)PPRVSK ddPTM_PC-9_AZD4547_30min_R2 2 SRSSSMTRSPPRVSK 15 3 Q9BRL6-2;Q9BRL6 Q9BRL6-2 SRSF8 Serine/arginine-rich splicing factor 8 2 S(0.075)RS(0.316)S(0.304)S(0.284)MT(0.535)RS(0.486)PPRVSK;S(0.123)RS(0.296)S(0.275)S(0.27)MT(0.592)RS(0.445)PPRVSK 67.102 0.015083000000000001 16827900.0 743.23 0.0 0.0 0.0 0.0 910.98 0.0 0.0 0.0 0.0 True False 979.5616798556389 0.0 0.0 0.0 0.0 854.0162765895691 0.0 0.0 0.0 0.0 0.0 SRST(ph)TELDDYSTNK ddPTM_PC-9_AZD4547_30min_R2 1 SRSTTELDDYSTNK 14 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.005)RS(0.263)T(0.662)T(0.07)ELDDYSTNK 203.06 1.3065e-09 29779000.0 24755.0 21514.0 43350.0 53575.0 49766.0 39579.0 50854.0 50401.0 52581.0 47690.0 True False 32626.575064012908 28467.97977079981 42775.15067561317 41224.11147549877 42856.849923689464 37104.11887323385 55379.90748274819 42612.68354976087 55360.32431376099 46020.3876157063 0.7089591538528847 0.6185949585762284 0.929482624805499 0.8957793189344931 0.9312579085940347 0.806253940820146 1.2033776843689075 0.9259522954391107 1.2029521519038024 1.0 15.489985514543486 -5.09073663232594 0.4104773059913913 1.079718372183552 0.41412223785542074 0.5683890965577576 0.11676240670810714 3.101577069120801 0.4972708401815849 0.09443179413782644 0.9904107056094019 8.114529952606483e-06 5.09073663232594 -0.6655961343281311 SRST(ph)TELDDYSTNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRSTTELDDYSTNK 14 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.084)RS(0.049)T(0.434)T(0.434)ELDDYSTNK 83.292 0.005938399999999999 17155000.0 21370.0 28683.0 31908.0 38898.0 57584.0 53285.0 47993.0 53210.0 48889.0 44725.0 True False 24987.518923260694 31530.458680656837 32668.807731763864 36718.67116901753 46300.82857020275 50490.640797118525 43446.755600769706 51813.293880655256 49603.90913609886 52833.28845709482 0.4729502867032914 0.5967915229479286 0.6183375800712035 0.6949912118159416 0.8763571210942701 0.955659628079393 0.822336766640074 0.9806940925649954 0.9388760492616601 1.0 15.689159588665431 -5.932778388301629 0.843639058252928 0.952359534899071 0.4845869608517625 0.9186618653676644 0.05058510654822495 0.19588103120503697 0.27269259010617813 0.023979420439113466 0.062255632692232964 1.167405168366922e-06 5.932778388301629 -0.4677725740473085 SRST(ph)TELDDYSTNK ddPTM_PC-9_Lapatinib_30min_R1 1 SRSTTELDDYSTNK 14 1 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.296)RS(0.197)T(0.311)T(0.195)ELDDYSTNK 61.648999999999994 0.036939 38233000.0 64099.0 87623.0 87846.0 86577.0 114270.0 102180.0 97862.0 112570.0 105150.0 105970.0 True False 63184.93650568302 87420.1143270411 80623.64097536603 92944.16139240535 107548.86326346386 97809.99959321375 102928.81551755636 117800.41315698903 93306.89972141208 124286.77330385093 0.5083802147732263 0.7033742368813468 0.6486904344862251 0.7478202138628177 0.865328308109931 0.7869703025767038 0.8281558268949539 0.9478113400610673 0.750738773250629 1.0 16.92331324625544 -3.8323798945782284 0.2690085624029437 0.939028590280291 3.011948657991867e-19 0.7391117007542691 0.06946797588073485 7.726590453625507 0.3112553075134076 0.08338220633092933 2.616494958242094 0.00014710251755139554 3.8323798945782284 -0.939028590280291 SRT(ph)GSESS(ph)QTGTSTTSSR ddPTM_PC-9_AZD4547_30min_R2 1 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 S(0.064)RT(0.627)GS(0.296)ES(0.082)S(0.91)QT(0.021)GTSTTSSR 200.99 1.0057e-12 11352000.0 6479.3 4593.7 7169.2 11465.0 10322.0 8870.9 7839.2 7272.2 5601.0 8673.9 True False 8539.582622187792 6078.523690300416 7074.131723727938 8821.921382484255 8888.968470689277 8316.201220661716 8536.873613457336 6148.448588531399 5897.057425331873 8370.22940112968 1.0202328052126333 0.7262075385269648 0.8451538643341346 1.0539641101465647 1.0619742954105398 0.9935451971650058 1.019909157125988 0.7345615387436788 0.7045275753775616 1.0 13.031051447621326 -7.763385456744067 24.999925603834466 0.789658402050307 0.9555309996193169 0.22533785134661355 0.12251290424862624 74.20305925222193 953183.0314826351 0.06656002309239832 0.03450159687398531 1.7243068093823576e-08 7.763385456744067 0.16587259756900985 SRT(ph)GSESSQTGTSTTSSR ddPTM_PC-9_AZD4547_30min_R2 3 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 S(0.142)RT(0.833)GS(0.025)ESSQTGTSTTSSR;S(0.051)RT(0.473)GS(0.473)ES(0.002)S(0.001)QTGTSTTSSR;S(0.05)RT(0.557)GS(0.377)ES(0.014)S(0.001)QTGTSTTSSR 149.18 7.0025e-05 46636990.0 0.0 0.0 1323.02 1172.6 589.37 1569.67 491.65 733.41 496.78 882.88 True False 0.0 0.0 1305.475890354089 902.2751864894054 507.5461487667252 1471.5182867618933 535.405897547747 620.0783365851896 523.0387766035292 851.9706399277574 0.0 0.0 1.5323015009822245 1.0590449297242375 0.5957319712446457 1.7271936587940053 0.6284323337634576 0.7278165555538029 0.6139164333736666 1.0 9.734659903840313 -5.238078216733196 23.874038664267054 0.978268958779619 6.801616939812314e-07 0.5371012618304982 0.3659285192358696 343.1227614425818 350653.03986547753 0.09372092320493176 0.24754775400868612 5.7799194128730555e-06 5.238078216733196 -0.978268278617925 SRT(ph)GSESSQTGTSTTSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 S(0.047)RT(0.799)GS(0.154)ESSQTGTSTTSSR;S(0.155)RT(0.815)GS(0.031)ESSQTGTSTTSSR;S(0.001)RT(0.999)GSESSQTGTSTTSSR 198.14 7.9048e-15 36560000.0 1686.54 2311.39 3310.74 1930.77 5800.199999999999 5678.099999999999 3767.9700000000003 6220.3 3559.54 4066.9799999999996 True False 1972.0379113166173 2540.849523755653 3389.680597651369 1822.5952165407975 4663.692447084084 5380.330440276228 3411.0406038595665 6057.023715952638 3611.5915385119197 4804.291279804035 0.4104742607107402 0.5288708314661748 0.7055526820159066 0.379368175323279 0.9707347401455463 1.1199009649755642 0.7099987084876963 1.2607528068530642 0.7517428332653542 1.0 12.230107907643502 -6.273412871210823 24.57262008780128 0.9765021683502438 0.5219443879073532 0.6386985222035961 0.17029429595452067 366.6499929625647 752456.5552779936 0.049591063019148694 0.0566768328584619 5.328281103494895e-07 6.273412871210823 -0.45455778044289064 SRT(ph)GSESSQTGTSTTSSR ddPTM_PC-9_Lapatinib_30min_R1 1 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 S(0.001)RT(0.98)GS(0.019)ESSQTGTSTTSSR 165.19 1.0534e-07 43641000.0 1066.0 534.44 972.13 572.68 911.25 754.02 993.5 407.95 701.95 661.92 True False 1050.7986445195424 533.2025370158957 892.2052239303183 614.7967976044772 857.6520665864309 721.7723223064694 1044.9385687671654 426.9048462946944 622.8889991388045 776.3319900470406 1.3535428888559276 0.6868228333391069 1.1492573220849196 0.7919251112751705 1.104749099073533 0.929721216644357 1.3459944742246794 0.5498998518260555 0.80234874657305 1.0 9.600529927198405 -7.776361501796571 24.999778932595284 0.7570933593378997 1.0287890737293903 0.21976486919114568 0.22654092814789295 351.2379139277009 588437.9088677225 0.11429532186659762 0.05526006482384192 1.673549252689183e-08 7.776361501796571 0.27169571439149065 SRT(ph)ILNRFCY(ph)GQCNS(ph)FYIPRHVK ddPTM_PC-9_Lapatinib_30min_R1 1 SRTILNRFCYGQCNSFYIPRHVK 23 3 Q9H772 Q9H772 GREM2 Gremlin-2 3 S(0.045)RT(0.956)ILNRFCY(0.992)GQCNS(0.875)FY(0.132)IPRHVK 49.528 0.0425 0.0 895.12 612.88 681.12 2399.6 884.06 889.1 911.94 918.71 3202.7 3006.6 True False 882.3554246550964 611.4609140152346 625.1209427992333 2576.074588830941 832.0613289288342 851.0752655933297 959.15579104331 961.3966205157466 2841.9782000738614 3526.2868039573236 0.2502222518216289 0.17340078899113695 0.1772745603385693 0.7305346195720607 0.23595962982791574 0.24135168603932697 0.27200163922200304 0.27263710354949955 0.8059407410890382 1.0 11.783934103001364 -8.370005864502557 3.343464211585375 0.9907493971919998 0.29480722966885764 0.7243323221783393 0.15213257675759662 0.1266846156211871 2.5146262258229704 0.15025107175204794 0.04037573549025683 4.265737585170563e-09 8.370005864502557 -0.6959421675231422 down SRT(ph)PLLPR ddPTM_PC-9_AZD4547_30min_R2 1 SRTPLLPR 8 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.23)RT(0.77)PLLPR 70.399 0.027568000000000002 3078900.0 3503.7 5142.1 5850.6 7534.0 3398.7 5065.5 3991.0 8008.2 5117.5 5064.3 True False 4617.803718512707 6804.1832657539135 5773.017221285872 5797.1526991396695 2926.849170832362 4748.753484230678 4346.191268408539 6770.716700128872 5388.000602416684 4887.000398452951 0.9449157646834933 1.3923025805170537 1.1813007470008396 1.1862394570245667 0.598905040351316 0.9717112946694177 0.8893372036115216 1.3854545013485648 1.1025169148998497 1.0 12.254733506874272 -6.058173483369243 24.999561020828214 0.9943373888770847 1.1929540701203847 0.1570982719529732 0.20832902394384825 503.2137626415859 216250.70688713185 0.06460899394575442 0.08341009701019873 8.746343238167884e-07 6.058173483369243 0.1986166812433 SRT(ph)PLLPR ddPTM_PC-9_Lapatinib_30min_R1 2 SRTPLLPR 8 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.118)RT(0.882)PLLPR;S(0.214)RT(0.786)PLLPR 75.652 0.028883 0.0 10891.1 10573.5 9409.5 8501.7 10162.6 7702.299999999999 7542.7 9738.2 11322.2 7723.4 True False 10735.790916816875 10549.017710383909 8635.887231720377 9126.943378839815 9564.85584844034 7372.890583938252 7933.224099285455 10190.672323046932 10046.97460794838 9058.379399216386 1.1851778826735384 1.1645590502972831 0.9533589675508007 1.0075691220914593 1.0559124791425458 0.8139304238654499 0.8757884550487844 1.1249995031041091 1.1091359905743752 1.0 13.145037250844673 -5.251035656998485 21.25248723187085 0.9892958879543022 1.1748688103154346 0.3906076806239164 0.09099692245349814 100.93376993302455 206174.22121293106 0.02539775693097397 0.06506817201064695 5.610019140481774e-06 5.251035656998485 0.18557292236113232 SRT(ph)PPSAASSR ddPTM_PC-9_AZD4547_30min_R2 1 SRTPPSAASSR 11 1 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 S(0.227)RT(0.773)PPSAASSR 82.515 0.0099896 1731200.0 2198.4 2239.9 3053.9 4495.3 2743.6 3105.1 1171.4 2186.0 2539.0 2376.9 True False 2897.4454704393465 2963.9038713681584 3013.4032906171874 3458.978036692669 2362.698497983249 2910.937606136546 1275.6523306975098 1848.2039292826998 2673.206356528767 2293.6854544720527 1.2632270326300097 1.2922015377432703 1.313782273302507 1.5080437598575767 1.030088277089886 1.2691093281605035 0.5561583556325652 0.8057791558468547 1.1654633599898163 1.0 11.163451844983808 -7.168602450471841 9.887280083804894 0.8659302370819457 1.2814298388270573 0.5391609932284676 0.17982923919921434 0.3507044290791328 35.34192871891526 0.06965100621371664 0.05394354491616056 6.782620989649798e-08 7.168602450471841 0.4154996017451116 SRT(ph)PPSAPSQSR ddPTM_PC-9_AZD4547_30min_R2 3 SRTPPSAPSQSR 12 1 Q9UQ35;I3L3Q8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.071)RT(0.906)PPSAPS(0.013)QS(0.01)R;S(0.013)RT(0.987)PPSAPSQSR;S(0.277)RT(0.722)PPSAPS(0.001)QS(0.001)R 132.24 0.00095656 123825300.0 19606.2 16519.9 24408.5 35610.9 28768.7 23907.0 19571.8 22735.0 19500.2 20908.5 True False 25840.56376570594 21859.63461074815 24084.827341769407 27401.35718792048 24774.66258890899 22412.091510710263 21313.652284399457 19221.828148326702 20530.940761552698 20176.499779052087 1.280725797273047 1.083420556098811 1.1937069167356311 1.3580827937445066 1.227896952405534 1.1108017622550788 1.0563602467127624 0.9526839818016127 1.0175670203643847 1.0 14.300388296838422 -7.1114788796714405 1.9879164378529286 0.9939845831309978 1.2252487818535656 0.7018552209086725 0.06848015488404217 0.20519571006134518 1.5995633962959737 0.03449831406798658 0.024628325261870854 7.736082994789959e-08 7.1114788796714405 0.23126419872256776 SRT(ph)PPSAPSQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 SRTPPSAPSQSR 12 1 Q9UQ35;I3L3Q8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.004)RT(0.996)PPSAPSQSR;S(0.003)RT(0.996)PPSAPS(0.001)QS(0.001)R;S(0.031)RT(0.967)PPSAPS(0.001)QS(0.001)R;S(0.191)RT(0.802)PPSAPSQS(0.007)R;S(0.032)RT(0.967)PPSAPSQSR;S(0.191)RT(0.806)PPSAPS(0.001)QS(0.001)R;S(0.073)RT(0.927)PPSAPS(0.001)QSR;S(0.213)RT(0.787)PPSAPSQSR 142.1 0.00082871 869791700.0 170686.6 156658.7 185078.9 183268.9 208578.7 168289.4 180314.1 152593.7 165842.2 155156.90000000002 True False 199580.47016598177 172210.74041471994 189491.88289163687 173000.93769879028 167709.20102972633 159464.00760744303 163233.44308696614 148588.27706138938 168267.32843238258 183285.61774865573 1.0889041519868274 0.9395758517772898 1.0338611682641239 0.943887140866835 0.91501560836983 0.870030117835651 0.8905960276207397 0.8106925076093657 0.9180607322017589 1.0 17.483734057822765 -6.046268997165645 1.6230082527178693 0.8857108915669776 1.0174094538581266 0.4588000760034123 0.05686483291947825 0.31163790762625926 1.6488304126265227 0.018475312164304626 0.029984792834722787 8.989406152522976e-07 6.046268997165645 0.13169856229114907 SRT(ph)PPSAPSQSR ddPTM_PC-9_Lapatinib_30min_R1 6 SRTPPSAPSQSR 12 1 Q9UQ35;I3L3Q8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.043)RT(0.947)PPS(0.001)APS(0.005)QS(0.004)R;S(0.004)RT(0.993)PPSAPS(0.004)QSR;S(0.03)RT(0.961)PPSAPS(0.008)QSR;S(0.01)RT(0.99)PPSAPSQSR;S(0.237)RT(0.763)PPSAPS(0.001)QSR;S(0.001)RT(0.998)PPSAPSQSR 161.49 0.00060994 296137300.0 103732.8 87812.40000000001 96979.6 80480.9 100567.79999999999 93296.40000000001 87736.6 83554.6 99885.3 74302.1 True False 102253.55124973434 87609.07578297795 89006.31164008174 86399.73386241206 94652.59972790224 89306.33045653065 92279.17184951928 87436.85174706396 88635.16567516084 87145.1189836752 1.1733709522949805 1.005323956232014 1.0213573941732204 0.9914466222554269 1.0861491823269345 1.0248001436920444 1.0589138316146638 1.0033476661319771 1.017098452659922 1.0 16.41113224051258 -4.756708691824988 24.999961840720974 1.0253539516379149 1.1733711758630432 0.7276418157798688 0.027540461380069034 76.59023536952058 404702.95086905325 0.006800184740128041 0.05388006090705034 1.7510208127812507e-05 4.756708691824988 0.1480172242251283 SRT(ph)PPVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRTPPVTR 8 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.058)RT(0.942)PPVTR 68.132 0.032026 3170900.0 5660.9 7369.7 5053.0 7558.1 9418.1 6986.5 4975.5 4376.8 6296.5 7258.7 True False 6619.1785621285235 8101.3151113494705 5173.482683609212 7134.644160690817 7572.690913396545 6620.115640969665 4504.184620499438 4261.91363760293 6388.5744006923105 8574.644850162413 0.7719478389828763 0.9447989103823959 0.6033465844957089 0.8320629350095683 0.8831492202564063 0.7720571238404438 0.5252910994225171 0.49703675336736597 0.7450541115497401 1.0 13.065861202767339 -7.024179449956338 22.46577038152167 0.6497521016038046 0.8070665675858137 0.08666281322062441 0.15449508903988357 356.0962659038156 330856.75638226187 0.056809963492008224 0.044335828883468854 9.458462580774432e-08 7.024179449956338 0.15731446598200916 SRT(ph)PSASNDDQQE ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SRTPSASNDDQQE 13 1 O43765 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 S(0.229)RT(0.75)PS(0.016)AS(0.005)NDDQQE;S(0.001)RT(0.856)PS(0.112)AS(0.031)NDDQQE;S(0.033)RT(0.82)PS(0.114)AS(0.033)NDDQQE 113.54 0.0034369 1727640.0 5733.009999999999 7284.42 8037.0 9547.1 10579.599999999999 9861.6 8803.0 7009.0 8958.2 8409.9 True False 6703.495360891097 8007.569076545356 8228.632560492231 9012.206939115815 8506.603326294056 9344.44033564538 7969.11611179913 6825.021176649359 9089.196727750632 9934.548297268224 0.6747659944171198 0.8060325277946715 0.8282845192624329 0.9071581987873538 0.8562647310933281 0.940600423495338 0.8021618973849527 0.6869986407460604 0.9149079007698775 1.0 13.278238657360397 SRT(ph)PVQDHR ddPTM_PC-9_AZD4547_30min_R2 6 SRTPVQDHR 9 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.218)RT(0.782)PVQDHR;S(0.357)RT(0.643)PVQDHR;S(0.236)RT(0.764)PVQDHR;S(0.247)RT(0.753)PVQDHR;S(0.077)RT(0.923)PVQDHR;S(0.364)RT(0.636)PVQDHR 87.21600000000001 0.0079735 405804720.0 976928.53 930676.26 1402613.7000000002 1682036.9000000001 1461038.96 1477506.4699999997 1098845.33 1316205.4900000002 1101045.47 1331566.28 True False 1287571.4811642403 1231499.1606787972 1384014.1258864892 1294269.2799160497 1258198.9197721996 1385117.7568622783 1196640.43562453 1112816.1749137493 1159244.4857153217 1284948.549834429 1.0020412734269781 0.9584034791412317 1.0770969203901783 1.0072537768790988 0.9791823337473892 1.0779558115698535 0.9312749804486119 0.866039480769203 0.9021719086454436 1.0 20.293279163463367 -7.430994208856049 6.8997788681637875 0.9102824116965483 1.0146279443194581 0.4679328066727535 0.04757364628766332 0.20082818809534878 12.88556807837447 0.01953298069111333 0.013052747758214129 3.706856646953269e-08 7.430994208856049 0.1043455326229098 SRT(ph)PVQDHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SRTPVQDHR 9 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.188)RT(0.812)PVQDHR;S(0.013)RT(0.987)PVQDHR;S(0.211)RT(0.789)PVQDHR 104.94 0.020471 48905230.0 133757.3 162325.1 174687.2 168453.6 195400.0 172780.1 177931.2 158799.0 134212.1 120054.6 True False 156399.76906290426 178439.66315878686 178852.40535289518 159015.6909259401 157112.7726906366 163719.20739401734 161076.26862566746 154630.6945114484 136174.69805815205 141819.54862830916 1.1028082558125185 1.2582162676772743 1.2611266012532898 1.1212536809202505 1.107835797040992 1.154419182528245 1.135783255437004 1.090334132403112 0.960196950104872 1.0 17.11369688406132 -7.799948843805401 0.7528617438625265 0.9750867693461637 1.1876451116436877 0.6180445786072499 0.05586552520176242 0.4499080026155469 0.49025118751115104 0.05451652169825937 0.025210163715037683 1.5850798903889815e-08 7.799948843805401 0.21255834229752402 SRT(ph)PVQDHR ddPTM_PC-9_Lapatinib_30min_R1 8 SRTPVQDHR 9 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.084)RT(0.916)PVQDHR;S(0.036)RT(0.964)PVQDHR;S(0.092)RT(0.908)PVQDHR;S(0.121)RT(0.879)PVQDHR;S(0.244)RT(0.756)PVQDHR;S(0.246)RT(0.754)PVQDHR;S(0.23)RT(0.77)PVQDHR;S(0.198)RT(0.802)PVQDHR 108.68 0.0017437000000000002 609951960.0 1202133.6 961313.5 1228727.8 982988.7000000001 1253132.3 1023369.3 931127.3 881593.89 1208604.9 914846.2 True False 1184990.9544196997 959087.6376536749 1127706.543310469 1055280.9681521738 1179425.5218668946 979602.1806293561 979336.5155531308 922555.9605461251 1072479.088988182 1072976.1467140645 1.1043963633755278 0.8938573710057139 1.0510080273117102 0.9835083206499219 1.0992094516535393 0.9129766618105524 0.9127290653686008 0.8598103167264308 0.9995367485778647 1.0 20.033186573284553 -6.794391721681865 24.979853704743377 0.9267310535707879 1.0180174147554335 0.2876787941926753 0.06876125122777363 234.6740003892903 177895.3787113444 0.023056325371280027 0.020335129738232146 1.6054924896556636e-07 6.794391721681865 0.09128636118464561 SRT(ph)SPAPWK ddPTM_PC-9_AZD4547_30min_R2 1 SRTSPAPWK 9 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.009)RT(0.651)S(0.341)PAPWK 74.69800000000001 0.019497999999999998 122730000.0 147120.0 139490.0 164750.0 151590.0 151340.0 156420.0 145370.0 188230.0 135670.0 141190.0 True False 193901.0997138996 184577.41462437817 162565.30735426245 116643.26754215332 130329.0533185538 146639.03267266043 158307.64838099427 159143.37859509743 142841.23922420564 136246.98107489166 1.4231588706344758 1.3547266381111258 1.1931663077723846 0.8561163456387877 0.9565647054367764 1.076273628345985 1.1619167421696954 1.1680506778173687 1.0483992973443519 1.0 17.055864737819697 -5.387547352133806 3.219091577707448 1.0475458335933123 1.394447326053649 0.7040524642387118 0.09005933589291398 0.1522517240630845 2.9253607608783985 0.02757119690784181 0.06620063936398878 4.0968743820745424e-06 5.387547352133806 0.34690149246033664 SRT(ph)SPAPWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRTSPAPWK 9 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.014)RT(0.754)S(0.232)PAPWK 66.538 0.034726 56295000.0 336480.0 370570.0 324330.0 343910.0 318520.0 284690.0 322490.0 239450.0 234980.0 258490.0 True False 393439.41821706825 407357.74058818753 332063.2572283742 324641.83767126396 256108.29251495146 269760.3552318976 291941.4125745884 233164.691218247 238416.13796151493 305352.1907942855 1.288477469880433 1.3340586800067296 1.0874762560720705 1.0631717978731445 0.8387308171877194 0.8834400517323749 0.9560809497229646 0.7635926587319921 0.780790657965624 1.0 18.220114670483255 -5.670666499224102 1.1377065710044219 0.857134559573867 1.3446350293061466 0.8268097897195716 0.07806984789646411 0.217936113524823 0.5281312159181344 0.02779558327743168 0.0880825619005889 2.134683537097426e-06 5.670666499224102 0.4875004697322797 SRT(ph)SPAPWK ddPTM_PC-9_Lapatinib_30min_R1 1 SRTSPAPWK 9 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.126)RT(0.437)S(0.437)PAPWK 69.45100000000001 0.029071 56595000.0 82077.0 115480.0 121360.0 100670.0 135960.0 141560.0 121860.0 121680.0 125590.0 113450.0 True False 80906.56692892144 115212.61315507018 111382.2492631473 108073.60762527556 127963.10010764444 135505.80879247744 128169.31453444072 127333.69701467948 111444.73167867001 133059.68133737706 0.6080472019452705 0.8658717050655257 0.8370848941140484 0.8122190474156592 0.9616970281417548 1.0183836864068398 0.9632468171140689 0.9569667966648803 0.8375544759956124 1.0 17.021713958185053 -3.9866895854712414 0.6426733829301141 0.9514022892645421 1.0510042201834496e-15 0.6905120296436345 0.06466228240225878 5.153279892355712 0.7591651588854769 0.02972811529730078 4.543385894930788 0.00010311228582284948 3.9866895854712414 -0.9514022892645411 SRT(ph)SPVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRTSPVTR 8 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.178)RT(0.713)S(0.107)PVT(0.002)R;S(0.03)RT(0.832)S(0.138)PVT(0.001)R 73.95100000000001 0.020581 1978800000.0 129657.0 130853.0 112377.0 114714.0 143295.0 116123.0 118432.0 131339.0 106152.0 90887.0 True False 151605.3692575202 143843.22106265 115056.49387214582 108286.94648780597 115217.3734017645 110033.30545714161 107213.26358657201 127891.49041517332 107704.2721801463 107364.09363890364 1.4120677045662278 1.3397702731644732 1.0716477918503549 1.0085955445403019 1.073146240020185 1.024861308168961 0.9985951536755024 1.1911942445610284 1.0031684572533792 1.0 16.712152060028984 -5.224062978421291 3.383558158346911 1.0480025850629762 1.3980641464236003 0.8531411052903627 0.05511778865527756 0.08187231701639215 1.9242431247751635 0.014378604523753223 0.04292487362222998 5.9694871487908354e-06 5.224062978421291 0.35006156136062416 SRT(ph)SPVTR ddPTM_PC-9_Lapatinib_30min_R1 2 SRTSPVTR 8 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.011)RT(0.868)S(0.12)PVTR;S(0.021)RT(0.85)S(0.129)PVTR 82.494 0.011814 2172600000.0 56211.0 60613.0 61227.0 61091.0 72406.0 45730.0 42299.0 74829.0 78213.0 58257.0 True False 55409.420832165095 60472.654322551614 56193.15240305472 65583.83593360188 68147.22143567314 43774.234501836625 44489.03524940343 78305.82851669476 69403.82832059737 68326.6448274269 0.810948949302473 0.8850523024405461 0.8224193145292319 0.959857404080757 0.9973740347970117 0.64066126197763 0.6511227847023617 1.1460511300455678 1.0157652039828842 1.0 16.060160664715923 -7.776651844562942 24.999996981807083 1.0606811489309498 0.8310643043556412 0.4611341826499863 0.11369289449030906 244.3931845042634 401627.2342138743 0.06700789700802612 0.03238271333682936 1.6724307937779954e-08 7.776651844562942 -0.22961684457530862 SRTDSLAAT(ph)PPAAK ddPTM_PC-9_AZD4547_30min_R2 2 SRTDSLAATPPAAK 14 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 SRTDS(0.001)LAAT(0.998)PPAAK;SRTDS(0.001)LAAT(0.998)PPAAK 75.564 0.012494 57656000.0 70705.0 55508.0 80691.0 123184.0 117475.0 96894.0 95852.0 99380.0 82647.0 100416.0 True False 93187.7192446386 73449.87548189823 79620.98461743718 94785.83197382816 101165.6240161036 90835.20286270807 104382.64231007168 84023.1045252125 87015.55169280544 96900.46640425178 0.9616849402548359 0.7579930025876057 0.8216780328514867 0.978177252299264 1.0440158625662164 0.9374072822700307 1.0772150659688837 0.8671073282009069 0.8979889872747546 1.0 16.564215989229865 -5.764167991923317 24.996072640921266 0.9721450498930218 0.8382060763833988 0.36326668391234573 0.07530638368463542 71.3838714791717 653938.027130028 0.02113327627126676 0.03300247572837412 1.7212026579925426e-06 5.764167991923317 -0.13393897350962292 SRTDSLAAT(ph)PPAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SRTDSLAATPPAAK 14 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 SRTDSLAAT(1)PPAAK;SRT(0.002)DS(0.029)LAAT(0.97)PPAAK;SRTDSLAAT(1)PPAAK 79.393 0.0092461 40433500.0 101011.0 75520.0 83491.0 133957.0 169760.0 167934.0 150324.0 149526.0 151635.0 129195.0 True False 118110.16724181017 83017.12650570752 85481.74208138083 126451.82358445352 136496.74663235675 159127.24540908894 136084.22246848725 145601.10093589305 153852.375009764 152617.03079294277 0.7738989982189574 0.543957159134735 0.56010617974448 0.8285564391303886 0.8943742773867971 1.0426571961354605 0.8916712752269059 0.9540291812742163 1.0080944060463162 1.0 17.219556438375655 -6.01748870610388 2.4703068464557054 0.9648666488545525 0.6183940607319811 0.8038572960188051 0.07451571799294117 0.11822207562692702 1.4444851508167715 0.02300555654660201 0.0345816793607475 9.605307968159725e-07 6.01748870610388 -0.3464725881225714 SRTDSLAAT(ph)PPAAK ddPTM_PC-9_Lapatinib_30min_R1 3 SRTDSLAATPPAAK 14 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 SRTDS(0.001)LAAT(0.999)PPAAK;SRTDSLAAT(1)PPAAK;SRT(0.004)DS(0.017)LAAT(0.979)PPAAK 114.58 0.0001236 63980900.0 180718.0 119017.0 129038.0 134988.0 153053.0 152222.0 121737.0 132655.0 171065.0 126068.0 True False 178140.92818037802 118741.42344888284 118428.99374108434 144915.46782676753 144050.72345377546 145711.81990681338 128039.94619628426 138818.63558088636 151797.8583056905 147858.6858249491 1.2048052989682343 0.8030737104579816 0.800960681344708 0.9800943855157346 0.974245933879854 0.9854802854079374 0.8659616138335737 0.9388602015929906 1.026641468228691 1.0 17.17385947020152 -8.25258243743828 21.169251874102507 1.0133207444715664 0.9356754042465086 0.05592076282445846 0.10923756906743415 202.95414262708428 485114.7766909328 0.0759878648340037 0.02747086196144509 5.590074071509953e-09 8.25258243743828 -0.07764534022505776 SRTGS(ph)ESSQTGTSTTSSR ddPTM_PC-9_Lapatinib_30min_R1 1 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 S(0.003)RT(0.01)GS(0.959)ES(0.027)S(0.002)QTGTSTTSSR 85.884 0.00084901 420380.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SRTGSES(ph)SQTGTSTTSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 S(0.009)RT(0.02)GS(0.35)ES(0.555)S(0.041)QT(0.024)GT(0.001)STTSSR 79.514 0.019275999999999998 5417900.0 0.0 0.0 0.0 570.86 865.0 2503.5 600.51 874.8 1138.2 577.03 True False 0.0 0.0 0.0 538.8765649530912 695.509459454456 2372.2120528401283 543.6253454840956 851.8374269272165 1154.844021737153 681.6409712330335 0.0 0.0 0.0 0.7905577682314299 1.0203457374288043 3.4801488656836286 0.7975244570477055 1.2496863640492608 1.6942115724765392 1.0 9.412868243675119 -6.089756289885379 2.183402199075144 1.62785801756739 0.0026920973065830273 0.49392384163775915 0.7035424293880693 0.26648034127257647 2.5095199867920748 0.23124955784473483 0.33677483204575465 8.13286774805969e-07 6.089756289885379 -1.625165920260807 SRTLAGYHSSHLNPSTLGGQEMTK ddPTM_PC-9_AZD4547_30min_R2 1 SRTLAGYHSSHLNPSTLGGQEMTK 24 1 K7EPI1 K7EPI1 QTRT1 0 54.672 0.010833 9671500.0 12895.0 8850.3 18328.0 28188.0 22312.0 18073.0 17112.0 19630.0 15553.0 21589.0 False True 16995.341767337766 11710.986397950623 18084.95874469754 21689.692100258704 19214.36393315434 16942.89245296635 18634.934849663485 16596.63455252487 16375.099827921193 20833.175681180182 0.8157825781064499 0.5621316009219773 0.8680845888048999 1.0411130992310627 0.9222964480884108 0.8132649919652839 0.894483641612906 0.7966444869716898 0.786010739721922 1.0 14.346595151250693 -5.382754720947597 7.637740547234487 0.8880765427749061 0.6900579585382035 0.40972755928970694 0.0968434239691679 0.248150825676402 14.322906682363033 0.025717329814610442 0.05381782856461906 4.142335578939506e-06 5.382754720947597 -0.1980185842367026 SRTPS(ph)ASNDDQQE ddPTM_PC-9_AZD4547_30min_R2 4 SRTPSASNDDQQE 13 1 O43765 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 SRTPS(0.85)AS(0.15)NDDQQE;S(0.027)RT(0.115)PS(0.744)AS(0.115)NDDQQE;S(0.003)RT(0.016)PS(0.689)AS(0.293)NDDQQE;S(0.004)RT(0.06)PS(0.875)AS(0.06)NDDQQE 160.87 0.00051902 164016400.0 210216.22 196054.90000000002 252089.6 363070.89999999997 308482.80000000005 286012.80000000005 224746.4 305396.29999999993 188012.1 266196.8 True False 277060.6051909943 259425.81236247 248746.72719158168 279370.5133944876 265655.28802072734 268128.37440224463 244748.39420853287 258204.31914382306 197950.03577169066 256877.33105600058 1.0785716437181203 1.0099210050804905 0.9683483013818515 1.0875639054875708 1.0341717851421195 1.0437992846624184 0.9527831560784025 1.0051658434878912 0.7706014188092625 1.0 17.970720055153947 -7.762025923933541 1.756351002804868 0.896828151421114 1.0329604099323686 0.38053825226696714 0.06709246300567025 0.36513028892118 2.1599248935255733 0.047622151096111225 0.018984395202165286 1.7297131059898724e-08 7.762025923933541 0.13613225851125454 SRTPS(ph)ASNDDQQE ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRTPSASNDDQQE 13 1 O43765 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 S(0.001)RT(0.003)PS(0.941)AS(0.055)NDDQQE 124.42 0.00074315 72318000.0 66323.0 36921.0 67194.0 93334.0 130710.0 145700.0 168910.0 135690.0 151040.0 126640.0 True False 77550.17396103984 40586.272877611555 68796.15979466419 88104.79857291079 105098.31380958584 138059.23550980882 152909.6219974995 132128.28127543884 153248.6742603932 149598.82951831183 0.518387571685828 0.27130073816950245 0.4598709763717978 0.5889404272519807 0.7025343323072 0.9228630728886118 1.0221311389256718 0.8832173466923117 1.024397548789876 1.0 17.190739361863344 -6.359330113492092 1.1794349573605247 0.9843661560850273 0.3887149834123149 0.9193744655588073 0.07258770973574946 0.11622239925012735 0.3353178291273566 0.030475282786511376 0.04058145895998905 4.371896646656371e-07 6.359330113492092 -0.5956511726727124 SRTPS(ph)ASNDDQQE ddPTM_PC-9_Lapatinib_30min_R1 2 SRTPSASNDDQQE 13 1 O43765 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 S(0.007)RT(0.027)PS(0.752)AS(0.213)NDDQQE;S(0.003)RT(0.016)PS(0.738)AS(0.243)NDDQQE 102.52 0.0089785 1873600.0 4436.0 2246.36 3691.7200000000003 4625.200000000001 6175.400000000001 5657.9 6059.9 5972.6 7826.2 7965.5 True False 4372.741826537229 2241.158691435948 3388.2010320513064 4965.3526372148945 5812.175113303534 5415.924806209084 6373.651970681576 6250.108800048275 6944.730942460442 9342.326061638423 0.46805707675871394 0.2398930070144546 0.36267210218277224 0.531489974172887 0.6221336180043598 0.5797190946319056 0.6822339456608292 0.6690099188158879 0.7433620809893355 1.0 13.189566082968648 -6.715503303408249 0.17717159311650665 1.1268850300315392 5.153872883603522e-20 0.8643548917916053 0.0736650345154306 2.5402185213573625 0.2051385494205658 0.35221529931743056 0.8262697903559074 1.9252924005190932e-07 6.715503303408249 -1.1268850300315392 down SRTPSAS(ph)NDDQQE ddPTM_PC-9_AZD4547_30min_R2 2 SRTPSASNDDQQE 13 1 O43765 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 S(0.015)RT(0.166)PS(0.268)AS(0.551)NDDQQE;SRT(0.043)PS(0.389)AS(0.568)NDDQQE 118.16 0.0011947000000000001 279595900.0 56923.0 49895.7 62646.3 94793.6 81035.9 69811.2 59755.0 67978.9 57610.6 59246.2 True False 75023.3299280471 66023.50926140633 61815.56912963474 72940.40006652065 69785.46406645316 65445.89462803761 65073.07923922634 57474.323004718906 60655.77870162905 57172.00857113978 1.312238835105727 1.154822279494563 1.0812208749447194 1.2758061486638184 1.2206229203862642 1.1447191775080379 1.138198234862698 1.0052878050139336 1.0609348913490486 1.0 15.80302135557798 -7.513620999447696 1.6069924423626591 1.0185327487870426 1.2000803347236093 0.6046273857547424 0.06359910757719126 0.2891465430289765 1.4466149138354618 0.04303891608247771 0.020942374303874845 3.0646367173615374e-08 7.513620999447696 0.18154758593656672 SRTPSAS(ph)NDDQQE ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRTPSASNDDQQE 13 1 O43765 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 SRTPS(0.313)AS(0.686)NDDQQE 109.95 0.0035223 155820000.0 18863.0 10900.0 20436.0 21380.0 36858.0 44991.0 48352.0 42804.0 50466.0 37689.0 True False 22056.133338767748 11982.079964409562 20923.271743961588 20182.147914895228 29635.939487366868 42631.59275787105 43771.74852183476 41680.44035458687 51203.96977770797 44521.71735404014 0.49540167472372343 0.26912888083644965 0.469956528800947 0.45331018465449624 0.6656513101617259 0.9575460088132118 0.9831549886936846 0.9361822236806542 1.1500897274588497 1.0 15.442221622956444 -6.561491474503537 1.530452493298398 1.0223379980257963 0.3941622035037776 0.9307879530280115 0.07546659509868264 0.08787331178697427 0.42245520544665344 0.029655030408706342 0.03169515748891981 2.744786224972645e-07 6.561491474503537 -0.6281757945220187 down SRTPSAS(ph)NDDQQE ddPTM_PC-9_Lapatinib_30min_R1 3 SRTPSASNDDQQE 13 1 O43765 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 SRTPS(0.016)AS(0.984)NDDQQE;SRTPS(0.151)AS(0.849)NDDQQE;SRT(0.002)PS(0.336)AS(0.662)NDDQQE 162.67 0.00058408 304545600.0 294122.0 213548.0 269961.2 240369.7 420829.7 494262.8 467028.8 485541.7 605498.8 495112.6 True False 289927.7663446312 213053.54272634952 247766.03221636772 258047.28958781325 396077.324429023 473124.33222686127 491209.26607453125 508101.73993912037 537301.1489589676 580692.1532139287 0.49927963506994555 0.36689585272880376 0.426673635669208 0.4443788126972466 0.6820779689149803 0.8147592999290295 0.8459030544081906 0.8749932939974379 0.9252770955922051 1.0 19.147414013736864 -6.549173469341998 1.3624424557347365 0.9073299165179867 0.412071441101647 0.9516188198987583 0.048987454907857136 0.08150193700448424 0.3132863355649597 0.02062554204728809 0.022473569687148108 2.823751864294759e-07 6.549173469341998 -0.49525847541633966 SRTPVQDHR ddPTM_PC-9_AZD4547_30min_R2 1 SRTPVQDHR 9 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 0 86.13600000000001 0.015421 225440.0 496.18 462.41 1013.5 2786.2 2884.8 1947.4 862.63 1894.9 669.28 821.67 False True 653.9549188148626 611.8749895796019 1000.0603277908634 2143.884636360891 2484.295315272662 1825.62877014921 939.4023988642591 1602.0867454701677 704.6567744377999 792.9035833968828 0.824759696523568 0.7716890204459219 1.2612634735568973 2.7038402666516683 3.1331619219447564 2.302459981739549 1.1847624585573946 2.0205315993234114 0.8887042374294435 1.0 9.631001635512229 -2.965415447650336 14.65112670811706 1.6847532656451094 1.0211317743137038 0.0 0.8207268354234376 0.0 0.0 0.20615188313850863 0.0 0.0010828905214567799 2.965415447650336 -0.6636214913314056 SRTPVQDHR ddPTM_PC-9_Lapatinib_30min_R1 2 SRTPVQDHR 9 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 0 ; 83.647 0.018165 584890.0 4445.8 3371.6 5177.799999999999 4723.8 5177.799999999999 5174.299999999999 2964.9700000000003 2615.13 3937.0 2763.9900000000002 False True 4382.402076740129 3363.793267350488 4752.101270885994 5071.204010134857 4873.251983946468 4953.007250882421 3118.4816388903705 2736.638486801433 3493.5736015520633 3241.7419887148294 1.3518664014582813 1.0376499052239643 1.4659097754938661 1.5643453512922252 1.5032818777408135 1.527884473263097 0.9619771251834497 0.8441876300853782 1.0776840395422929 1.0 11.66255355552549 -7.271836333043222 24.21613895589127 0.9579777678369985 1.4056363738207673 0.6751932163810705 0.1485481710218828 306.98141277059176 715004.0817468812 0.06834334658906635 0.046679514482471776 5.347658517330109e-08 7.271836333043222 0.44765860598376883 SRTS(ph)PAPWK ddPTM_PC-9_Lapatinib_30min_R1 2 SRTSPAPWK 9 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.021)RT(0.052)S(0.927)PAPWK;S(0.173)RT(0.173)S(0.654)PAPWK 67.252 0.021823 120053000.0 174159.0 290660.0 299040.0 245990.0 333380.0 290360.0 296600.0 309200.0 296130.0 244740.0 True False 171675.46072315134 289986.99462809745 274454.0855277823 264080.92519858485 313771.2438502984 277941.979662219 311956.4967250543 323566.5607900956 262776.72101285565 287042.98290444835 0.5980827644210315 1.0102563445162815 0.9561428143991361 0.9200048108700599 1.0931158834659527 0.9682939358066144 1.0867936696048732 1.127240796887222 0.9154612258900943 1.0 18.130907262139033 -4.761397563946011 9.668532025672727 1.012112934788446 0.5960363762699726 0.7578784791712246 0.06958310748648311 0.036717149618020216 63.06166868894148 0.01752498173170399 0.09956996165631955 1.7322175567937102e-05 4.761397563946011 -0.41607655851847347 SRTSPVTR ddPTM_PC-9_AZD4547_30min_R2 3 SRTSPVTR 8 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 ;; 106.18 0.0064545 15870000.0 34670.0 31377.8 38191.0 56646.0 48079.0 38617.0 30226.2 42638.0 31812.9 37541.0 False True 45694.33881920127 41520.06022367774 37684.56238644391 43587.13987197582 41404.06075394978 36202.27288530968 32916.27324409175 36049.27682376747 33494.46494667746 36226.70101659109 1.2613441891458512 1.1461176165244082 1.0402427306087063 1.2031771772984186 1.1429155731013863 0.9993256871148652 0.908619121266846 0.9951023916656843 0.9245794954207306 1.0 15.14476581234297 -6.812392399065509 3.71131434662091 0.956483332927786 1.1555613374225637 0.7376018233449197 0.05804990621025883 0.12224599081336021 3.4494845330527752 0.02132201103344806 0.019268029396501143 1.5403081059977335e-07 6.812392399065509 0.19907800449477775 SRTSPVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRTSPVTR 8 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 ; 96.665 0.0078426 5254900.0 32040.0 31290.0 33168.0 35590.0 39854.0 36594.0 33159.0 31890.0 31201.0 26096.0 False True 37463.73918115456 34396.26441159406 33958.85091034047 33596.00768433679 32044.8947943328 34674.94621994476 30017.939469629375 31052.92129024799 31657.255598507236 30826.998224177645 1.2152898867646384 1.1157837737382108 1.1015944745377937 1.0898241677643272 1.0395074655436272 1.1248239600814964 0.9737548642049187 1.0073287403602325 1.026932799888327 1.0 14.911906793550681 -1.522878745358136 0.267178769069282 0.9947615967079566 2.4289497722864755 0.7470987779513137 0.03501337412057845 25.815192327710815 0.35938917284100086 0.041477186073313854 17.011706062410557 0.02999999999462587 1.522878745358136 1.4341881755785189 SRTSPVTR ddPTM_PC-9_Lapatinib_30min_R1 2 SRTSPVTR 8 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 ; 83.99799999999999 0.018544 15172600.0 22681.1 16630.4 18308.300000000003 18393.1 21344.4 19972.6 16793.9 18783.1 21601.9 15435.5 False True 22357.66335479568 16591.893330568742 16803.06224608176 19745.789931582927 20088.96435670497 19118.418456404594 17663.405968816212 19655.831397077756 19168.86654390844 18103.50560848909 1.2349908265453147 0.9165016814637535 0.9281662131892552 1.0907163705533218 1.1096726120981155 1.0560616750072755 0.9756898111785319 1.0857472481937835 1.0588483224442333 1.0 14.143981471016772 -4.740257936421508 24.88988577873435 1.028445812812046 1.2349916404695023 0.4881896734086386 0.06451796702346602 1538.6952591392467 1807991.6417466213 0.01738120251762674 0.7999102217798112 1.81862042173723e-05 4.740257936421508 0.20654582765745633 SRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSK ddPTM_PC-9_Lapatinib_30min_R1 1 SRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSK 35 3 A0A0J9YXH7;Q99795 A0A0J9YXH7 GPA33 Cell surface A33 antigen 0 28.673000000000002 0.039358 7890600.0 25880.0 25756.0 18442.0 21693.0 22080.0 19643.0 19370.0 27842.0 26278.0 23134.0 False True 25510.94645418925 25696.36356444394 16925.76994817867 23288.37558572661 20781.297810950226 18802.914680069465 20372.883821862106 29135.64096221811 23318.29492039246 27132.681075882654 0.9402294739263747 0.9470631926339409 0.6238148711084592 0.8583145735062239 0.7659139085013621 0.6929987724944277 0.7508614340353889 1.0738209350094716 0.8594172781958995 1.0 14.727743991996716 -7.750280342449954 24.999998907920915 0.9749643424148783 0.7932959087938204 0.37409757260672605 0.10702600601901391 226.12723975070125 506603.7638668682 0.05217507021565768 0.029767060260827108 1.7771318791372837e-08 7.750280342449954 -0.1816684336210579 SRWDETPASQMGGST(ph)PVLTPGK ddPTM_PC-9_AZD4547_30min_R2 2 SRWDETPASQMGGSTPVLTPGK 22 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 SRWDETPAS(0.024)QMGGS(0.105)T(0.865)PVLT(0.006)PGK;SRWDETPASQMGGS(0.313)T(0.68)PVLT(0.007)PGK 96.181 9.944e-05 59693000.0 130000.0 114449.0 171226.0 224387.0 201900.0 172281.0 156779.0 208890.0 141867.0 169287.0 True False 171337.2958320212 151442.40107782223 168955.43136291901 172658.04389459186 173869.67004768117 161508.2418353065 170732.02727883283 176610.85031466704 149365.79999277944 163360.31365695226 1.0488306002632939 0.9270452393709466 1.0342501650536506 1.056915477385556 1.0643323715256692 0.9886626575317734 1.0451254864590966 1.0811123360447275 0.9143334549812353 1.0 17.317698015787784 SRWDETPASQMGGST(ph)PVLTPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SRWDETPASQMGGSTPVLTPGK 22 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 SRWDETPASQMGGS(0.016)T(0.969)PVLT(0.015)PGK;SRWDETPASQMGGS(0.08)T(0.918)PVLT(0.002)PGK 99.836 6.6281e-05 54393000.0 159340.0 127518.0 156554.0 197538.0 211685.0 199461.0 206892.0 183417.0 177616.0 150966.0 True False 186313.11489154704 140177.14430289707 160286.84109435117 186470.58628683683 170206.84384348764 189000.91402897716 187293.69199163304 178602.49809637578 180213.2979835405 178334.94075380196 1.044737021831068 0.786032976546177 0.8987966150482711 1.0456200310418498 0.9544222973021566 1.059808656845884 1.050235535447868 1.0015003080240075 1.0105327493412057 1.0 17.4442298690075 -5.752868470949943 24.805932205924996 1.0180135644196155 0.897473230161877 0.36023090908395206 0.06507803029145064 160.45528233761877 464384.5000619339 0.016959015377003152 0.028787680057570354 1.7665727583027866e-06 5.752868470949943 -0.12054033425773858 SRWDETPASQMGGST(ph)PVLTPGK ddPTM_PC-9_Lapatinib_30min_R1 2 SRWDETPASQMGGSTPVLTPGK 22 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 SRWDETPASQMGGS(0.01)T(0.987)PVLT(0.004)PGK;SRWDETPASQMGGS(0.15)T(0.816)PVLT(0.034)PGK 151.42 1.6323e-05 27539700.0 170172.0 177731.0 208601.0 177165.0 170756.0 178630.0 157643.0 158560.0 196988.0 145172.0 True False 167745.31607427678 177319.47478926033 191450.63100314603 190194.30510511485 160712.46779921255 170990.4113068682 165804.98318687713 165927.27645173867 174801.13706439888 170264.78677046904 0.985202632065145 1.0414336290703585 1.1244288066518255 1.1170501470836272 0.9438972722872299 1.0042617416681545 0.9738066592148376 0.9745249126316547 1.0266429153084085 1.0 17.377420570025514 -6.263759224813402 24.999973272641686 0.9860996910561026 1.0693005769542636 0.4673980796431775 0.041714684006155474 193.7717741648554 2088191.3723215892 0.013507187062928588 0.016082080812499712 5.448046117252759e-07 6.263759224813402 0.08320088589816099 SRWS(ph)GSQQVEQPTGSVLWMAPEVIR ddPTM_PC-9_AZD4547_30min_R2 1 SRWSGSQQVEQPTGSVLWMAPEVIR 25 1 P04049;P04049-2;H7C155 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 S(0.171)RWS(0.414)GS(0.414)QQVEQPTGS(0.001)VLWMAPEVIR 61.903999999999996 0.0034825000000000004 10345000.0 9097.7 6538.7 12912.0 15355.0 14045.0 14521.0 9943.4 12656.0 9388.7 8868.8 True False 11990.579356084436 8652.20690375238 12740.77844344908 11815.141982385137 12095.094184347116 13612.999574477086 10828.3433370818 10700.306005947774 9884.967514589063 8558.306011452623 1.4010458775415118 1.0109719017027552 1.4887033048829432 1.3805468005671047 1.4132579704630337 1.5906184654136382 1.2652437670014884 1.250283174220313 1.1550144971868401 1.0 13.063109549661377 -8.290112444058918 1.353618207069256 1.0109374020678852 1.3675954875582703 0.4123195440544284 0.14293292895044965 0.43087060284040507 1.5672274940021467 0.1397053286074185 0.04356082717066513 5.1272861520606264e-09 8.290112444058918 0.35665808549038513 SRWS(ph)GSQQVEQPTGSVLWMAPEVIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SRWSGSQQVEQPTGSVLWMAPEVIR 25 1 P04049;P04049-2;H7C155 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 S(0.075)RWS(0.589)GS(0.33)QQVEQPTGS(0.006)VLWMAPEVIR 65.782 0.0012607 8676900.0 11578.0 8927.0 13066.0 13648.0 13122.0 13317.0 13391.0 13629.0 12271.0 8260.1 True False 13537.926724076393 9813.213563512309 13377.542993080935 12883.346807413009 10550.83829706516 12618.633076761333 12122.507537555632 13271.253191119153 12450.440160548773 9757.590743084378 1.3874251421818753 1.0057004666307974 1.3709883254288127 1.3203409680349616 1.0812954319223718 1.2932119627690573 1.2423668769001581 1.3600952879198236 1.2759748270209972 1.0 13.252309259081537 SS(ph)AIGIENIQEVQEK ddPTM_PC-9_AZD4547_30min_R2 1 SSAIGIENIQEVQEK 15 0 J3KPC5;P47736-3;F2Z357;P47736;A0A0A0MQY8;X6R8W7;P47736-2;P47736-4 J3KPC5;P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 S(0.018)S(0.982)AIGIENIQEVQEK 95.662 0.0027951 7742400.0 36541.0 28026.0 35195.0 73428.0 58475.0 42682.0 34914.0 51247.0 29396.0 43763.0 True False 48160.27789998371 37084.85642169917 34728.291303995524 56500.30905129116 50356.75560197202 40013.08779270235 38021.27836261982 43327.95368890691 30949.81254687658 42230.870690420496 1.1404045692789426 0.8781456743706535 0.8223437200377962 1.3378911712589314 1.1924157560264268 0.9474843198480105 0.9003195468390955 1.025978223525836 0.7328717604180756 1.0 15.366010371604661 -6.975030138403115 23.95864839192083 0.9179493065764721 1.0645942677960412 0.19471539771186952 0.155946211142238 276.8886422406567 265673.64143980335 0.05857801016096338 0.05165835078278605 1.0591802195044883e-07 6.975030138403115 0.14664496121956905 SS(ph)AIGIENIQEVQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSAIGIENIQEVQEK 15 0 J3KPC5;P47736-3;F2Z357;P47736;A0A0A0MQY8;X6R8W7;P47736-2;P47736-4 J3KPC5;P47736-4 RAP1GAP Rap1 GTPase-activating protein 1 1 S(0.23)S(0.77)AIGIENIQEVQEK 184.92 4.5705e-07 4803200.0 22206.0 21461.0 20778.0 21399.0 25111.0 16463.0 15578.0 17346.0 10741.0 9771.2 True False 25965.03721150805 23591.506249192076 21273.426321003804 20200.08340649405 20190.67981082177 15599.651298544855 14102.339065046786 16890.6858796062 10898.066805024398 11542.641211223356 2.249488374139295 2.0438568450220167 1.8430293319971542 1.7500399637175528 1.749225280535411 1.3514802213012316 1.2217601506433846 1.4633293689474411 0.9441571132287979 1.0 13.494685761794686 -5.818005296616631 0.3223666261343834 0.9425628375456452 2.681493836484518 0.9123541277006243 0.1228379748553865 0.9965237499168359 0.13905127911165538 0.14001632165884867 0.646001212247647 1.5205289853839976e-06 5.818005296616631 1.7389309989388726 up SS(ph)AVTVFKLR ddPTM_PC-9_AZD4547_30min_R2 1 SSAVTVFKLR 10 1 Q8TD57-2;Q8TD57-3;Q8TD57 Q8TD57-2 DNAH3 Dynein heavy chain 3, axonemal 1 S(0.088)S(0.895)AVT(0.016)VFKLR 63.816 0.022549 4400100.0 8229.8 7646.1 10034.0 11629.0 12105.0 8466.2 8859.8 9264.8 10685.0 14320.0 True False 10846.705209525891 10117.552297365095 9900.942603900865 8948.113716258991 10424.429697509562 7936.807175637897 9648.305036293157 7833.138043924221 11249.78728614016 13818.661158668767 0.7849317010513354 0.7321658864916968 0.7164907287483328 0.6475383985116121 0.7543733490396843 0.57435427965892 0.6982083810804314 0.5668521685264938 0.8141011026298236 1.0 13.754330224413383 -8.54432069544892 7.389421510973228 0.9999923617522015 0.6851130147583865 0.6783804219736822 0.06767779671971251 0.1389230085511705 44.10759316179069 0.0646872381283151 0.016729022201794484 2.8554811958018108e-09 8.54432069544892 -0.31487934699381503 SS(ph)DEENGPPS(ph)SPDLDR ddPTM_PC-9_Lapatinib_30min_R1 1 SSDEENGPPSSPDLDR 16 0 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 2 S(0.392)S(0.608)DEENGPPS(0.529)S(0.471)PDLDR 197.94 6.737399999999999e-11 5395700.0 23814.0 34017.0 29960.0 34295.0 38281.0 38498.0 37234.0 37730.0 37091.0 36903.0 True False 23474.40799304726 33938.23572649824 27496.804448944433 36817.168704766256 36029.38684334175 36851.530283221226 39161.794332638776 39483.073540136815 32913.42099445459 43281.63437984339 0.5423641766166641 0.7841255583985884 0.6352995870634202 0.8506418307048108 0.8324405341800339 0.8514357373801782 0.9048132052720436 0.912236196850376 0.7604477387707577 1.0 15.40146735808514 -3.7260569262336207 0.3589501332211366 0.9133484112956727 3.966371492443566e-15 0.647129111707999 0.07621642192161608 8.599839474946455 0.4898257418754552 0.06372752908665598 3.943538490430033 0.00018790704968028304 3.7260569262336207 -0.9133484112956687 SS(ph)DEENGPPSSPDLDR ddPTM_PC-9_Lapatinib_30min_R1 1 SSDEENGPPSSPDLDR 16 0 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 S(0.027)S(0.968)DEENGPPS(0.005)SPDLDR 252.37 1.9887999999999996e-48 5512500.0 11021.0 11980.0 12994.0 7111.6 10139.0 8372.2 6113.8 5154.6 10307.0 6345.2 True False 10863.838518996125 11952.261046049001 11925.683478290512 7634.6107876021515 9542.64395404095 8014.140522551428 6430.342648946854 5394.101533792455 9146.117122478321 7441.959365552457 1.4598089005004455 1.6060637338835726 1.6024924206778712 1.0258871908037344 1.2822757402052205 1.0768858211786938 0.8640658102369919 0.7248227608928931 1.2289931553260174 1.0 12.86146679777076 -6.035290385498166 0.992552044693897 0.9513959473673337 1.5958789650586251 0.6495641646325833 0.16997651884160267 0.3482006785360483 0.7012345604498467 0.07356395725177774 0.15124962297916716 9.219547676526023e-07 6.035290385498166 0.6444830176912915 SS(ph)DGGSEEPPDRR ddPTM_PC-9_AZD4547_30min_R2 1 SSDGGSEEPPDRR 13 1 Q9HCD6;Q9HCD6-2;Q9HCD6-3;Q9HCD6-4 Q9HCD6 TANC2 Protein TANC2 1 S(0.06)S(0.94)DGGSEEPPDRR 238.01 6.4034e-26 5153300.0 5946.6 6355.1 9238.5 12031.0 10471.0 8734.5 8300.3 10589.0 9174.9 9301.4 True False 7837.495103036128 8409.261794246073 9115.991453671335 9257.438827097081 9017.282392616487 8188.3303342242325 9039.010620188274 8952.713361013033 9659.86648307042 8975.760817125816 0.8731844868328188 0.93688568195814 1.015623259064341 1.0313820762061552 1.004625967239618 0.9122714498586949 1.0070467344608578 0.9974322559856087 1.0762170115584324 1.0 13.131818516697916 -4.985718954114937 2.767298436872066 1.002943423857509 0.8715065507427426 0.5486824493833153 0.03845463747164922 0.24803080780377212 3.4233314277087614 0.010612590266247082 0.060473749692115095 1.0334299550794864e-05 4.985718954114937 -0.13143687311476637 SS(ph)DGSLSHEEDLAK ddPTM_PC-9_AZD4547_30min_R2 1 SSDGSLSHEEDLAK 14 0 A0A2R8Y7R9;Q13136-2;Q13136;E9PJZ7;H0YEF9 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 S(0.119)S(0.881)DGSLSHEEDLAK 258.09 6.2371e-45 5414100.0 22049.0 18618.0 33704.0 42523.0 42191.0 33218.0 27460.0 39930.0 30501.0 35054.0 True False 29060.123352309463 24635.904405166457 33257.062938197596 32719.979323800948 36333.50791967172 31140.873208799672 29903.886802931236 33759.73600011811 32113.22059097436 33826.77012960722 0.8590865530751427 0.7282960894810242 0.9831580967019082 0.9672806241457401 1.0741051475047703 0.9205984813058847 0.8840302130045091 0.9980183112596246 0.9493433889174936 1.0 15.045877810880214 -5.2721362944680905 24.974284530730205 0.97048699052403 0.7936913211494674 0.617662763168523 0.056125145854554345 398.0348931954025 929300.1168422414 0.014848370822418654 0.03141224725947168 5.343966235938917e-06 5.2721362944680905 -0.1767956693745626 SS(ph)DPWSNSHFPHEN ddPTM_PC-9_AZD4547_30min_R2 1 SSDPWSNSHFPHEN 14 0 Q92545 Q92545 TMEM131 Transmembrane protein 131 1 S(0.25)S(0.749)DPWS(0.001)NSHFPHEN 99.37100000000001 0.0012594000000000001 2947000.0 14634.0 18335.0 31926.0 37203.0 34279.0 23885.0 26495.0 32746.0 24994.0 27106.0 True False 19287.307593890742 24261.430189533086 31502.640379922163 28626.423130620293 29519.95254861051 22391.467174188077 28853.00367238393 27685.858128221073 26315.1318137377 26157.027190424295 0.7373661943109324 0.9275301055012414 1.2043662359098215 1.0944065975930173 1.1285668028596665 0.8560402147834776 1.1030689176691528 1.058448191633813 1.0060444416011955 1.0 14.674910963912101 -4.91612655970502 3.7106277671592394 1.057708184440664 0.7405451251865197 0.5540149881770216 0.08831779273161833 0.17747072901435465 4.424003257747374 0.02272924646194238 0.12357607825298846 1.2130353028887064e-05 4.91612655970502 -0.31716305925414423 SS(ph)DTEEESR ddPTM_PC-9_AZD4547_30min_R2 2 SSDTEEESR 9 0 C9J8Q2;C9JVB3;F8WDM0;C9J367;C9J713;Q96IZ7-2;Q96IZ7 C9J8Q2 RSRC1 Serine/Arginine-related protein 53 1 S(0.033)S(0.851)DT(0.116)EEESR;S(0.092)S(0.513)DT(0.394)EEESR 86.189 0.011855 2614800.0 10377.900000000001 8440.900000000001 7744.4 3902.8 7908.9 7417.6 5806.1 7539.299999999999 8212.7 10706.6 True False 13677.856326270243 11169.255854203975 7641.704195898934 3003.06975765892 6810.885752551293 6953.776299403709 6322.831652093921 6374.274420878794 8646.806555440648 10331.765192835412 1.3238644191948135 1.0810597846289929 0.7396320041417601 0.2906637638011176 0.6592180160341157 0.6730482322832717 0.611979805394581 0.6169588934617921 0.8369147376129683 1.0 13.334799140760152 -2.6969649565636815 8.515592701741973 0.7548054227815998 0.9507320619963299 0.0 0.2771303115307694 0.0 0.0 0.0681182543690523 0.0 0.002009254933841152 2.6969649565636815 0.19592663921473008 SS(ph)DTEEESR ddPTM_PC-9_Lapatinib_30min_R1 1 SSDTEEESR 9 0 C9J8Q2;C9JVB3;F8WDM0;C9J367;C9J713;Q96IZ7-2;Q96IZ7 C9J8Q2 RSRC1 Serine/Arginine-related protein 53 1 S(0.224)S(0.773)DT(0.003)EEESR 150.15 0.00023091 1520200.0 3461.8 5057.5 939.5 4045.2 5695.0 2635.3 9515.6 7245.5 4828.4 4050.2 True False 3412.4340971836327 5045.789669481875 862.2579365748757 4342.697502391616 5360.031296800795 2522.594362184345 10008.271207811611 7582.1523809981845 4284.5747466939265 4750.271673447731 0.7183660918296279 1.06221075684702 0.18151760485501914 0.9141998186473619 1.1283631053696141 0.5310421246609364 2.1068839628171503 1.59615131559309 0.901964148838712 1.0 12.213794309837834 -7.236605009173765 24.995475374491722 1.4509292950942356 0.7678813358285429 0.38244908852251935 0.39955217285153743 774.7685383234168 779795.6092276904 0.1524219149855552 0.11801558746487772 5.7995592654108396e-08 7.236605009173765 -0.6830479592656927 SS(ph)EPVVIMK ddPTM_PC-9_AZD4547_30min_R2 1 SSEPVVIMK 9 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(0.41)S(0.59)EPVVIMK 65.278 0.045411 6503000.0 39507.0 51337.0 57116.0 83508.0 64662.0 68334.0 55077.0 61549.0 48702.0 64815.0 True False 52069.404203351165 67930.68130024876 56358.60452106858 64256.520785738765 55684.79744736584 64061.06417755778 59978.74630171318 52038.016305316 51276.28829289644 62545.84657815061 0.8324997909859738 1.0860942015609276 0.9010766918095654 1.0273507243274849 0.8903036811211447 1.0242257109353203 0.9589565028394035 0.8319979527384741 0.8198192381779831 1.0 15.932626463460018 -7.718246284120202 10.194668106714278 0.8694959836040643 0.9651073108229337 0.13934286930628914 0.08380275178225319 0.6224416577395961 143.10265040977797 0.036475023312481626 0.02095281008301012 1.9131706770990456e-08 7.718246284120202 0.09561132721886934 SS(ph)FMSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSFMSR 6 0 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5;B1AL79;A0A3B3IUG4 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 S(0.222)S(0.777)FMS(0.002)R 95.815 0.034554 5608300.0 26463.0 35972.0 44920.0 32343.0 33248.0 27729.0 30738.0 40982.0 37236.0 32456.0 True False 26085.63276728015 35888.70904411309 41226.850996214394 34721.612113085124 31292.418008083012 26543.095309456097 32329.46323781092 42886.17333214653 33042.08956753688 38065.97635509844 0.6852742334503741 0.94280279873358 1.0830367415675808 0.9121429538332232 0.8220574120093941 0.6972918561670097 0.8493007754805902 1.1266274357994364 0.8680215964856323 1.0 15.216214461944267 -7.717593550224955 24.99744811452768 0.9979939281130463 0.8628095837878439 0.21764405400571873 0.12309927142766168 223.57505194619574 127464.7097880593 0.061714016404635384 0.03563033140874193 1.9160482873889327e-08 7.717593550224955 -0.13518434432520243 SS(ph)FPVEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSFPVEQR 8 0 Q9H0K1 Q9H0K1 SIK2 Serine/threonine-protein kinase SIK2 1 S(0.229)S(0.771)FPVEQR 86.189 0.012662 2978200.0 19859.0 25113.0 21527.0 23215.0 24497.0 21433.0 18177.0 21711.0 19878.0 14287.0 True False 23220.736466871043 27606.052673964892 22040.28532160214 21914.3388140455 19696.988703185907 20309.01574935988 16455.142969916247 21141.109254705996 20168.678144518657 16877.120004170218 1.3758707920032187 1.6357087386440121 1.3059269185830367 1.298464359359335 1.1670823397782868 1.203346053375319 0.9749970946376098 1.2526491042003716 1.1950307955110302 1.0 14.04278111592912 -5.801241063769982 1.2651875143272215 1.1332295565726724 1.50900026043967 0.6412727897245738 0.1070528879545009 0.29469298468401744 0.9406057269807144 0.036538429901471395 0.08837744636213567 1.5803705797173273e-06 5.801241063769982 0.3757707038669975 SS(ph)FSITR ddPTM_PC-9_AZD4547_30min_R2 2 SSFSITR 7 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.077)S(0.62)FS(0.301)IT(0.003)R;S(0.146)S(0.569)FS(0.284)ITR 88.177 0.017446 5210100.0 17532.0 24336.9 34791.0 47524.0 40475.0 36851.0 34414.0 40183.0 29654.0 34670.0 True False 23106.81131174608 32203.3269909816 34329.648607964424 36568.07603848071 34855.74489935559 34546.7011444842 37476.779331248195 33973.64066347973 31221.44990015912 33456.21385272668 0.6906582858855942 0.9625514450840058 1.026106802134951 1.093012981069895 1.0418317222860185 1.0325944620200544 1.1201739532219614 1.0154657909897022 0.9332033217385288 1.0 15.02998656835196 -4.711457309220162 2.264608503586267 1.038854842423145 0.5594280019134523 0.8196255923636133 0.04798798546374194 0.3193987378927095 1.643829113051569 0.013035530652046368 0.33109842619142754 1.943312708433652e-05 4.711457309220162 -0.47942684050969264 SS(ph)FSITR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSFSITR 7 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.071)S(0.858)FS(0.071)ITR 80.455 0.043223000000000004 0.0 10966.0 10753.0 11879.0 11550.0 17488.0 15003.0 12932.0 14103.0 13548.0 8731.7 True False 12822.327211627364 11820.486775898722 12162.240411358378 10902.890945605224 14061.351938658416 14216.216268727965 11706.98734042785 13732.811193363663 13746.113869702123 10314.688089900837 1.2431134223226554 1.1459858672287162 1.1791185836502889 1.0570257530404918 1.3632357872678629 1.3782497487875696 1.134982196106368 1.3313840490057598 1.3326737318563235 1.0 13.332412575184227 -6.264514920185494 24.998363516415385 1.2733096236769716 1.1572025254581697 0.14066899727122628 0.11740984476949974 466.1944905102895 3789287.2199494685 0.03457283324951819 0.040910377913911576 5.438574471786511e-07 6.264514920185494 -0.11610709821880194 SS(ph)FSQHAR ddPTM_PC-9_AZD4547_30min_R2 1 SSFSQHAR 8 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 S(0.199)S(0.668)FS(0.133)QHAR 75.652 0.014773 23803000.0 2269.7 3242.0 13164.0 27868.0 16224.0 14810.0 9120.8 19307.0 10058.0 15510.0 True False 2991.4173873072173 4289.91309923459 12989.436758795202 21443.463156307986 13971.577646624968 13883.92835879111 9932.53353066916 16323.546780723262 10589.645346186033 14966.999620876588 0.1998675394589217 0.28662478839451844 0.867871790460728 1.4327162223213903 0.9334922162446531 0.9276360466679798 0.6636289024030476 1.0906358785467267 0.7075329467781344 1.0 13.869497418185219 -5.271796385964821 4.28729669594242 0.966119710269709 0.2250432205023475 0.6716599795631324 0.19958237637722218 0.1124083797244614 5.248354458160484 0.05406812767106826 0.13527590484861235 5.34815042585752e-06 5.271796385964821 -0.7410764897673615 SS(ph)FSSDPDEK ddPTM_PC-9_AZD4547_30min_R2 2 SSFSSDPDEK 10 0 P46013 P46013 MKI67 Antigen KI-67 1 S(0.156)S(0.834)FSS(0.01)DPDEK;S(0.009)S(0.987)FSS(0.004)DPDEK 211.63 1.1692000000000001e-05 18487900.0 130362.0 284350.0 163706.0 159815.0 174469.0 222390.0 169094.0 189061.0 183963.0 171959.0 True False 171814.40430195333 376260.5767326822 161535.15147639997 122972.12086713653 150246.9909041548 208483.91814392703 184143.03842151663 159845.96663957706 193686.90861209208 165938.7677502458 1.0354084619969635 2.26746637831487 0.9734624022249357 0.7410692662984076 0.9054363422192656 1.256390661269197 1.1097047478300552 0.9632828350284063 1.1672191570303208 1.0 17.34029145239507 -5.313182060167795 24.997351923509633 1.011627630472176 1.6514387982071204 0.408102043118986 0.3067780721069125 265.0109331709041 128028.65956302908 0.07552451515737259 0.15721704221608276 4.862033421330685e-06 5.313182060167795 0.6398111677349443 SS(ph)FSSDPDEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSFSSDPDEK 10 0 P46013 P46013 MKI67 Antigen KI-67 1 S(0.205)S(0.794)FSSDPDEK 158.06 0.00011211 5248300.0 62493.0 105030.0 71922.0 81620.0 96509.0 71465.0 133200.0 104300.0 82625.0 67750.0 True False 73071.83060698777 115456.68428091191 73636.89324570376 77047.09601561046 77598.75424565343 67717.24959305763 120582.33171551109 101562.23551498471 83833.23431385729 80032.53869129495 0.9130265239847467 1.4426217906976129 0.9200869352619094 0.9626971388824729 0.9695900631738146 0.8461214738452769 1.5066663345595794 1.2690117941495653 1.0474893797536844 1.0 16.288299052854754 -7.24232792142138 24.98709916310509 1.2282095875950472 1.0207921854275614 0.1837543389551164 0.20003605045516637 1374.3350610257337 1796864.4868705454 0.07746975531024926 0.05991021840972838 5.7236369486044346e-08 7.24232792142138 -0.20741740216748572 SS(ph)FYVNGLTLGGQK ddPTM_PC-9_Lapatinib_30min_R1 1 SSFYVNGLTLGGQK 14 0 P07737;K7EJ44;I3L3D5 P07737 PFN1 Profilin-1 1 S(0.189)S(0.645)FYVNGLT(0.166)LGGQK 146.67 0.00019725 10072000.0 45423.0 43026.0 46764.0 37426.0 44572.0 45748.0 42930.0 44116.0 41148.0 32990.0 True False 44775.25969044201 42926.37594050956 42919.24443426023 40178.43288947609 41950.36259192361 43791.464683796694 45152.705341896755 46165.79041337598 36513.4789323506 38692.27754358815 1.1572143728164148 1.109430063716243 1.1092457502898418 1.0384096114325072 1.0842050469803728 1.1317882395127592 1.1669694370157124 1.1931525705967727 0.9436890576218198 1.0 15.239758032190286 -8.272209012193356 24.999697976431698 0.9718445050973041 1.1203764480209535 0.6620584434004636 0.04337124585708225 536.233608928899 1244753.2007198718 0.04424345352164144 0.011869378065416993 5.343071523818131e-09 8.272209012193356 0.14853194292364935 SS(ph)GFISELPSEEGK ddPTM_PC-9_AZD4547_30min_R2 1 SSGFISELPSEEGK 14 0 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(0.038)S(0.962)GFISELPSEEGK 129.17 2.341e-05 15454000.0 26984.0 26578.0 32437.0 44477.0 40812.0 45396.0 33149.0 44291.0 36508.0 40634.0 True False 35564.350697932714 35168.81873888247 32006.864186040715 34223.51481279998 35145.95826639902 42557.38094366514 36099.19678187791 37446.84365592866 38437.738347440834 39211.416028027015 0.9069897060721424 0.8969025427121778 0.8162639207715241 0.8727946674595518 0.896319537179628 1.0853313971942902 0.9206297664964561 0.9549985042407777 0.9802690706187916 1.0 15.2589861218815 -6.545250348560135 24.97058758568846 0.982275896612164 0.8725708061862701 0.6005229954656253 0.04519968851151859 167.16147485276716 186579.84198376394 0.01499117873913594 0.014992054635533844 2.8493752748624174e-07 6.545250348560135 -0.10970509042589383 SS(ph)GFISELPSEEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSGFISELPSEEGK 14 0 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(0.032)S(0.968)GFISELPSEEGK;S(0.04)S(0.96)GFISELPSEEGK;S(0.011)S(0.989)GFISELPSEEGK;S(0.226)S(0.774)GFISELPSEEGK 244.23 6.2836e-35 42004900.0 105064.0 110790.0 104525.0 138655.0 157537.0 129449.0 147269.0 124837.0 119735.0 107572.0 True False 122849.26009141146 121788.49901439775 107017.2724132697 130886.60987557533 126668.75573881702 122660.46655805953 133318.61418477207 121560.16102573505 121485.89785863481 127073.95206051653 0.9667540680005519 0.9584064793735093 0.8421652957035977 1.030003456674135 0.9968113345407992 0.9652683698673733 1.049141952563824 0.9566095887837373 0.956025179737697 1.0 16.95530880781353 -5.7915322058324294 24.999998527879647 0.9928921136055592 0.9260381651821334 0.37199501843092464 0.04217348161998784 220.91796732408517 183529.54604910017 0.011948659886555031 0.017725119260082318 1.616098377189375e-06 5.7915322058324294 -0.06685394842342574 SS(ph)GFISELPSEEGK ddPTM_PC-9_Lapatinib_30min_R1 2 SSGFISELPSEEGK 14 0 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(0.205)S(0.795)GFISELPSEEGK;S(0.121)S(0.879)GFISELPSEEGK 269.78 8.846399999999999e-57 34727000.0 103267.0 100800.0 101111.0 86516.0 96558.0 98725.0 91636.0 92838.0 102587.0 83518.0 True False 101794.39364315147 100566.60379313366 92798.04387974695 92878.67524891546 90878.64828033211 94502.76188921552 96380.46370160842 97151.59240178151 91032.57177099874 97953.9750192602 1.039206358120088 1.0266720035951553 0.947363737525716 0.9481868931878793 0.9277688655561258 0.9647669925659874 0.9839362178273787 0.9918085752281016 0.9293402514099042 1.0 16.57981641848655 -5.211976826705056 6.035943133522829 0.960580476096795 1.0344136875227665 0.5949459204657567 0.023535030268796185 0.1458125324982587 12.802993439923487 0.006186140942127137 0.016617165347001125 6.137947554483603e-06 5.211976826705056 0.07383321142597155 SS(ph)GGGYGGGPAGGHGGNR ddPTM_PC-9_AZD4547_30min_R2 1 SSGGGYGGGPAGGHGGNR 18 0 Q9H2U1-3;Q9H2U1-2;Q9H2U1 Q9H2U1-3 DHX36 ATP-dependent RNA helicase DHX36 1 S(0.417)S(0.583)GGGYGGGPAGGHGGNR 133.35 2.117e-06 0.0 4959.7 3146.3 6236.3 8792.9 7911.7 4448.8 5551.9 7110.1 6662.1 9810.4 True False 6536.78143183134 4163.279945750092 6153.602587273964 6765.832753950787 6813.297020882806 4170.615832720452 6046.008344544567 6011.397418843972 7014.24500505329 9466.940882053355 0.6904850799505077 0.43977035429073974 0.6500096138700364 0.714679941307851 0.719693627093298 0.44054524948251883 0.6386443540601474 0.6349883762599472 0.7409199119802592 1.0 13.208682597654969 -8.689999743353374 1.5926726211661844 0.9995914526687997 0.6100191070584227 0.6053078539994458 0.09465203193900788 0.44518951899389303 2.2247424659179056 0.09221771254047657 0.02659040662538551 2.041739151236345e-09 8.689999743353374 -0.389572345610377 SS(ph)GGGYGGGPAGGHGGNR ddPTM_PC-9_Lapatinib_30min_R1 1 SSGGGYGGGPAGGHGGNR 18 0 Q9H2U1-3;Q9H2U1-2;Q9H2U1 Q9H2U1-3 DHX36 ATP-dependent RNA helicase DHX36 1 S(0.433)S(0.566)GGGY(0.001)GGGPAGGHGGNR 114.9 0.00044264 0.0 5096.2 7196.2 7552.7 8135.6 7694.5 5039.9 8435.2 8022.6 7834.2 7851.2 True False 5023.52725347138 7179.537641033209 6931.746160265109 8733.919163566008 7241.924637969042 4824.355225580719 8871.933382249417 8395.359283941209 6951.829898216713 9208.269458933597 0.5455452054129127 0.7796837042021864 0.7527740354665805 0.9484864884240124 0.7864588096890601 0.5239155138863002 0.9634745618398606 0.9117195496268057 0.7549550900112125 1.0 13.168714335918859 -3.1648114555247244 0.0630594437947931 1.2661237922384851 1.1563481923700024e-10 0.28507501940239066 0.13287775842097113 338.4171253156803 2.206108612584906 10.85227575407014 42.53110354763523 0.0006842086249377623 3.1648114555247244 -1.2661237921228503 SS(ph)GGREDLESSGLQR ddPTM_PC-9_AZD4547_30min_R2 1 SSGGREDLESSGLQR 15 1 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 S(0.051)S(0.948)GGREDLESSGLQR 110.6 0.0024614999999999997 31479000.0 24360.0 31873.0 45133.0 68713.0 55266.0 39278.0 43004.0 42885.0 40118.0 49130.0 True False 32105.97328052331 42175.323939513946 44534.506930621654 52872.279455267315 47593.269860600034 36821.9404508168 46831.272690213176 36258.10864926283 42238.55557747974 47409.973654008165 0.6771987159248081 0.8895875844037372 0.9393489069542351 1.1152142762432722 1.003866195073837 0.7766707638257415 0.987793687294191 0.7647780805336405 0.8909213045704526 1.0 15.532902970900146 -4.762233166336886 3.2911567219695668 0.9309867446538833 0.6359716353237937 0.370582544280184 0.10019014318479343 0.4139026685049862 6.770600726851654 0.026941397218398336 0.32254339998091947 1.728887895447239e-05 4.762233166336886 -0.29501510933008956 SS(ph)GGREDLESSGLQR ddPTM_PC-9_Lapatinib_30min_R1 1 SSGGREDLESSGLQR 15 1 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 S(0.414)S(0.586)GGREDLESSGLQR 122.96 0.00020236 24433000.0 24232.0 22324.0 26780.0 21997.0 23838.0 22518.0 22673.0 24058.0 24739.0 22412.0 True False 23886.44723639544 22272.31014958246 24578.25177378944 23614.732759840892 22435.895707311192 21554.957632021815 23846.89700015899 25175.822508046964 21952.633306780943 26285.884337887157 0.9087176573308858 0.8473106654235812 0.9350361379458548 0.8983807604221936 0.853533988771807 0.8200202570682995 0.9072130385123574 0.9577696601122069 0.8351491250815373 1.0 14.682000651968183 -10.855137261341914 3.1727767474511204 1.000868353576526 0.8855487757384821 0.39672647347051626 0.04261087186440145 28082999.896584507 39828561.96688994 231990.1068919428 0.011076893818642424 1.3959271003045028e-11 10.855137261341914 -0.11531957783804381 SS(ph)GSETEQVVDFSDR ddPTM_PC-9_AZD4547_30min_R2 1 SSGSETEQVVDFSDR 15 0 O95251-2;O95251-4;O95251 O95251-2 KAT7 Histone acetyltransferase KAT7 1 S(0.155)S(0.562)GS(0.283)ETEQVVDFSDR 151.39 0.00014456 9400500.0 25899.0 25450.0 27354.0 33160.0 41901.0 36651.0 28077.0 31660.0 31072.0 37587.0 True False 34134.343267334705 33676.21479812475 26991.268087213895 25515.47431689294 36083.76941390733 34359.20717610078 30575.798607643843 26767.674474423726 32714.402485254748 36271.0905705924 0.9410895214441081 0.9284588433475031 0.7441537506208228 0.7034658709043665 0.9948355245530734 0.9472890568103921 0.8429798532838673 0.7379892375258829 0.901941517903481 1.0 15.14653250332833 -5.036970142966696 24.745472908257675 0.8505712096299685 0.9379320525686314 0.07906286117349826 0.10041979959174295 1045.1973903048035 699589.6833811543 0.02655032168666169 0.070295117209087 9.183957325135697e-06 5.036970142966696 0.08736084293866297 SS(ph)GSPEPSPAIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGSPEPSPAIAK 13 0 Q66K64;K7ELE9 Q66K64 DCAF15 DDB1- and CUL4-associated factor 15 1 S(0.321)S(0.446)GS(0.233)PEPSPAIAK 83.137 0.009729600000000001 19422000.0 38162.0 34222.0 39148.0 39723.0 44433.0 36688.0 30635.0 36054.0 29626.0 24987.0 True False 44622.07286614295 37619.33399468113 40081.43678961678 37497.44909370361 35726.67261495934 34764.01669446719 27733.03102180693 35107.62070237067 30059.22420311449 29516.945303016844 1.5117442678454351 1.2744995665535948 1.3579127642832394 1.2703702469466276 1.2103783859811474 1.1777647157449607 0.9395630454677306 1.1894056224978815 1.0183717825313794 1.0 14.849255804734334 -5.537009723677695 0.35752409636933596 0.9962940332180094 1.6307013162708182 0.7759378877246329 0.07833993649973033 1.7740091025733102 0.2710937837949523 0.07791339566280699 0.46396096751837135 2.9039576353003268e-06 5.537009723677695 0.6344072830528088 SS(ph)GSPYGGGYGSGGGSGGYGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGSPYGGGYGSGGGSGGYGSR 22 0 P51991;P51991-2;H7C1J8 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 1 S(0.007)S(0.579)GS(0.413)PYGGGYGSGGGSGGYGSR 148.64 3.4817e-16 0.0 3212.9 8416.2 2130.7 1871.1 9015.4 3871.7 3074.6 3498.5 8514.8 3794.7 True False 3756.7805123324456 9251.70471527191 2181.503968724749 1766.268333188048 7248.897087590405 3668.661236261682 2783.3516298236536 3406.6680819671533 8639.312841581022 4482.649071171328 0.838071518132645 2.063892258435126 0.486655085885346 0.3940233342260088 1.6171011766701269 0.8184136607648949 0.6209166913653485 0.7599676057347452 1.9272784249701589 1.0 12.130135845594795 -11.55392726171272 2.576632907604957 0.952748461730424 1.0394096684189176 0.0 0.5688817683741371 319873507.0713499 106188339.22051698 89465889.18726723 0.14585581437007314 2.7930115926729954e-12 11.55392726171272 0.08666120668849353 SS(ph)GTNFQGLPSK ddPTM_PC-9_Lapatinib_30min_R1 1 SSGTNFQGLPSK 12 0 Q68EM7-6;Q68EM7-5;Q68EM7;Q68EM7-2;C9IZD3;Q68EM7-4 Q68EM7-6 ARHGAP17 Rho GTPase-activating protein 17 1 S(0.173)S(0.827)GT(0.001)NFQGLPSK 140.27 0.0001051 0.0 9002.1 20269.0 17982.0 14035.0 16370.0 17267.0 17062.0 18691.0 16554.0 15016.0 True False 8873.728403217045 20222.068375823634 16503.589372527334 15067.180719387503 15407.148784658297 16528.530661342942 17945.38687499284 19559.452094850196 14689.514198651994 17611.495592437695 0.5038600132874228 1.1482311805765608 0.9370918719483374 0.8555310161084382 0.8748347750360318 0.9385080656318721 1.0189587125524147 1.110607102740834 0.8340866976090101 1.0 14.104229809568867 -7.005866927556903 3.5528684835405313 0.9992224891390526 0.8838145129997036 0.11563538407765028 0.16068317365295298 0.5812161110338497 15.71062974231048 0.06048724751717879 0.04922646365804952 9.86581738447979e-08 7.005866927556903 -0.11540797613934906 SS(ph)IDSQASLSGPLSGGAPGAGAR ddPTM_PC-9_AZD4547_30min_R2 3 SSIDSQASLSGPLSGGAPGAGAR 23 0 A6NKD9 A6NKD9 CCDC85C Coiled-coil domain-containing protein 85C 1 S(0.195)S(0.805)IDSQASLSGPLSGGAPGAGAR;S(0.38)S(0.557)IDS(0.063)QASLSGPLSGGAPGAGAR;S(0.211)S(0.787)IDS(0.003)QASLSGPLSGGAPGAGAR 229.07 5.459499999999999e-47 10961400.0 29003.4 33526.6 39310.0 57231.2 48782.6 48430.2 35247.4 54840.5 35603.2 36210.9 True False 38225.87789180338 44363.41780160346 38788.7237153023 44037.43105322568 42009.97803896986 45401.85193800979 38384.350316738455 46366.16083432196 37485.112466626626 34943.16741274014 1.0939442735768243 1.2695877645433118 1.1100517379303196 1.2602587090364854 1.202237265521991 1.2993055667144946 1.0984794212657343 1.3269020603271655 1.072745124214461 1.0 15.092722766382854 -8.486472020113442 7.3728798520886425 1.0000560517180848 1.2072195213491028 0.43770242195064535 0.07977572066335734 0.16456169680387667 27.502203498595154 0.06951939179127357 0.017979380154996744 3.262330676315812e-09 8.486472020113442 0.20716346963101806 SS(ph)IDSQASLSGPLSGGAPGAGAR ddPTM_PC-9_Lapatinib_30min_R1 2 SSIDSQASLSGPLSGGAPGAGAR 23 0 A6NKD9 A6NKD9 CCDC85C Coiled-coil domain-containing protein 85C 1 S(0.215)S(0.785)IDSQASLSGPLSGGAPGAGAR;S(0.201)S(0.799)IDSQASLSGPLSGGAPGAGAR 293.12 2.363899999999999e-142 13335000.0 26437.0 28888.0 28556.0 21512.4 29998.0 26143.0 30115.0 29084.0 28940.0 21096.3 True False 26060.003532047955 28821.111610873435 26208.235909347688 23094.493659262673 28233.576618337163 25024.924832309538 31674.207346173305 30435.34881636204 25680.472448289747 24742.767345947228 1.0532372215154213 1.1648297544047443 1.0592281591994397 0.9333836161639156 1.141084027650679 1.0114036349458109 1.2801400467179926 1.2300705248860222 1.0378981497595543 1.0 14.59471924659776 -7.225460188431612 24.990344807231 1.1561998822519415 1.0630920409029656 0.11629585883795401 0.09759768884591694 1054.108043401475 732160.8803816745 0.037055602624403584 0.028702144792476247 5.9503130049496465e-08 7.225460188431612 -0.09310784134897587 SS(ph)INSVDGESPNGSSDR ddPTM_PC-9_AZD4547_30min_R2 1 SSINSVDGESPNGSSDR 17 0 Q9NUY8-2;Q9NUY8;E9PGE5 Q9NUY8-2 TBC1D23 TBC1 domain family member 23 1 S(0.02)S(0.979)INS(0.001)VDGESPNGSSDR 231.38 1.1017e-29 35909000.0 18173.0 13152.0 23234.0 23459.0 26415.0 19795.0 22009.0 24339.0 19822.0 18001.0 True False 23951.635978117836 17403.126798622263 22925.90197917409 18050.88998793702 22747.73320608965 18557.215520747464 23967.758362917466 20577.96680457987 20869.750452584965 17370.790469077976 1.3788454832124382 1.0018615347184028 1.3197961267211678 1.039151903885416 1.3095393238772444 1.068300003605562 1.3797736151145716 1.1846304197388737 1.2014277928074455 1.0 14.08437578586436 -9.122190574456619 2.6123210852091443 1.0000008124403987 1.2049059770425499 0.18514979511675933 0.13143591781365668 38.20461485207113 163.8480848463819 0.11439598902360718 0.03069819512059027 7.547609553867068e-10 9.122190574456619 0.20490516460215114 SS(ph)INSVDGESPNGSSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSINSVDGESPNGSSDR 17 0 Q9NUY8-2;Q9NUY8;E9PGE5 Q9NUY8-2 TBC1D23 TBC1 domain family member 23 1 S(0.102)S(0.891)INS(0.004)VDGES(0.003)PNGSSDR;S(0.22)S(0.774)INS(0.006)VDGESPNGSSDR 180.76 1.7303e-06 46301000.0 20258.1 28441.0 23462.0 23641.0 24937.0 25403.0 20919.8 28826.0 23974.0 18080.6 True False 23687.396214286753 31264.434519979135 24021.423060130477 22316.47141515612 20050.773861752325 24070.82196057431 18938.125097763885 28069.348043671627 24324.57439564798 21358.46965404915 1.1090399545454366 1.4637956289181986 1.1246790359615715 1.0448534832609297 0.9387739003084937 1.1269918842715847 0.8866798700708215 1.314202211034826 1.1388725311149113 1.0 14.382520660394762 -5.499642037986962 20.060677534853852 1.0687422237213473 1.2883734806183895 0.2910045508696384 0.13668575760778345 72.74870097601448 62802.48279732214 0.03523930748183386 0.07208659079643413 3.164885204037625e-06 5.499642037986962 0.21963125689704222 SS(ph)INSVDGESPNGSSDR ddPTM_PC-9_Lapatinib_30min_R1 1 SSINSVDGESPNGSSDR 17 0 Q9NUY8-2;Q9NUY8;E9PGE5 Q9NUY8-2 TBC1D23 TBC1 domain family member 23 1 S(0.027)S(0.773)INS(0.197)VDGES(0.003)PNGSSDR 148.52 7.1232e-05 17591000.0 12317.0 12692.0 14789.0 12164.0 11766.0 11085.0 9133.3 9018.4 14382.0 11834.0 True False 12141.35732133884 12662.61245379415 13573.105507190883 13058.58113791447 11073.947012846033 10610.920390397085 9606.177584419884 9437.427787287837 12762.147710825957 13879.491132186178 0.8747696299314137 0.9123254111550158 0.9779252984077497 0.940854460264178 0.7978640504453249 0.7645035606377987 0.6921130964335866 0.6799548843258877 0.9194968021003932 1.0 13.760667054488007 -6.29178076920263 5.973992203323325 0.784218750619809 0.9293203842112393 0.24564468184231625 0.09512789808114097 0.21596079717652275 25.17148154581348 0.02903472565589287 0.0337865082419175 5.107627667113359e-07 6.29178076920263 0.14510163359143036 SS(ph)ISGSLPSSGSLQAVSSR ddPTM_PC-9_AZD4547_30min_R2 1 SSISGSLPSSGSLQAVSSR 19 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 S(0.21)S(0.79)ISGSLPSSGSLQAVSSR 208.59 2.7296999999999993e-72 0.0 8765.8 8003.4 9380.4 9743.0 15991.0 8470.5 8627.1 13945.0 11558.0 12538.0 True False 11553.142060033304 10590.34253498277 9256.00976695552 7496.901877849463 13770.925674752201 7940.838295958142 9394.89518709279 11790.120674221054 12168.932283875347 12099.048436270185 0.9548802222660439 0.8753037555610854 0.7650196472648308 0.6196273960996357 1.1381825395020413 0.6563192417804794 0.7764986838906306 0.9744667720212579 1.005775978827861 1.0 13.562605966697486 -7.833103392462487 6.230763629156285 0.9967250980659791 0.8237243788006792 0.23165617041913078 0.13944504701694382 0.31867566841461525 21.118896307740588 0.07683863839135517 0.036616330066732365 1.4685766120729796e-08 7.833103392462487 -0.17300071926529992 SS(ph)ISGSLPSSGSLQAVSSR ddPTM_PC-9_Lapatinib_30min_R1 2 SSISGSLPSSGSLQAVSSR 19 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 S(0.221)S(0.778)IS(0.001)GSLPSSGSLQAVSSR;S(0.23)S(0.769)ISGSLPSSGSLQAVSSR 148.19 3.1657e-14 7841400.0 20807.0 25913.0 24953.0 31193.0 21209.0 22001.3 17945.5 15622.7 22126.0 27838.5 True False 20510.288364463508 25853.00004058997 22901.460661365487 33487.03727679761 19961.528318498324 21060.355686535273 18874.630181994118 16348.587675470331 19633.936882890768 32650.347632530425 0.6281797852598835 0.7918139289528399 0.7014155230172233 1.0256257499516963 0.6113726121130212 0.6450269970648727 0.5780835902399034 0.5007171090326092 0.6013392905908587 1.0 14.99481073196611 SS(ph)ITEPEGPNGPNIQK ddPTM_PC-9_AZD4547_30min_R2 2 SSITEPEGPNGPNIQK 16 0 Q13625-2;Q13625;Q13625-3 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 S(0.384)S(0.608)IT(0.007)EPEGPNGPNIQK;S(0.411)S(0.563)IT(0.027)EPEGPNGPNIQK 157.09 4.4216000000000005e-05 109477000.0 109726.0 111791.0 132517.0 125433.0 116725.0 137128.0 134377.0 167526.0 135309.0 136831.0 True False 144616.58555741812 147925.25455784544 130759.73799493049 96516.35977053171 100519.74857016152 128553.36448239771 146336.2926772572 141638.70606450742 142461.15750120181 132040.58833811517 1.095243420054292 1.1203013892898943 0.9902995710689745 0.7309597827857531 0.7612791629855624 0.9735897582735109 1.1082674995550243 1.0726906616154606 1.0789194390470511 1.0 17.010621946393677 -7.10891206999567 5.565654871264685 1.0696331127870204 0.9343256633695304 0.1976816810537564 0.11898992737510372 0.42372109953827763 18.28942954239184 0.05334250671592008 0.041263100236827006 7.781940931828887e-08 7.10891206999567 -0.13530744941749007 SS(ph)ITEPEGPNGPNIQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSITEPEGPNGPNIQK 16 0 Q13625-2;Q13625;Q13625-3 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 S(0.182)S(0.817)ITEPEGPNGPNIQK;S(0.122)S(0.878)ITEPEGPNGPNIQK;S(0.147)S(0.853)ITEPEGPNGPNIQK 338.92 1.4237999999999993e-189 50928000.0 89104.0 131957.0 112528.0 98434.6 112830.0 80710.0 104853.0 83143.0 74828.0 71755.6 True False 104187.54731578 145056.81888656836 115211.09428481669 92919.62849127915 90721.7714569321 76477.42551816528 94920.5647700189 80960.5843472905 75922.21793933198 84764.32226298304 1.229143872495506 1.711295684480631 1.359193245565887 1.0962115429059185 1.070282508429265 0.9022360289850783 1.1198174212438803 0.9551257201834119 0.8956860140258274 1.0 16.37116953437119 -5.770475115989098 2.5506729917424105 0.9945411758549223 1.484673127869892 0.7130033616754919 0.126682216707821 0.13525864313579497 1.7947596718009893 0.03574006217898996 0.06451807130122929 1.6963867982872415e-06 5.770475115989098 0.4901319520149696 SS(ph)ITEPEGPNGPNIQK ddPTM_PC-9_Lapatinib_30min_R1 2 SSITEPEGPNGPNIQK 16 0 Q13625-2;Q13625;Q13625-3 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 S(0.093)S(0.454)IT(0.454)EPEGPNGPNIQK;S(0.386)S(0.614)ITEPEGPNGPNIQK 179.65 5.2165e-06 55680900.0 93584.0 116336.0 113258.0 108026.0 134281.0 127525.0 123595.0 120244.0 117972.0 108810.0 True False 92249.47499879618 116066.6311396624 103946.3644285228 115970.59240417201 126382.85558660356 122071.05302529447 129994.14434502042 125830.97521230363 104684.75105976641 127617.66351978855 0.7228582035941433 0.9094871974494735 0.8145139282573117 0.9087346469573114 0.9903241612553617 0.9565372822106714 1.0186218800727642 0.9859996785851837 0.8202998564029803 1.0 16.96146850031679 -3.5292335379304545 0.5489671687327029 0.9646922168631338 2.296491726580462e-12 0.5277757877460276 0.06387687009159233 11.683422002313806 0.9268984432597241 0.033011332040750206 9.762433647181787 0.0002956422249696725 3.5292335379304545 -0.9646922168608373 SS(ph)LEGPTILDIEK ddPTM_PC-9_AZD4547_30min_R2 1 SSLEGPTILDIEK 13 0 A0A0G2JR96;A0A0G2JQT1;Q7L576;Q7L576-2 A0A0G2JR96 CYFIP1 Cytoplasmic FMR1-interacting protein 1 1 S(0.235)S(0.765)LEGPTILDIEK 113.37 0.0012134000000000001 0.0 6220.9 8571.0 8055.6 8682.7 7398.0 10983.0 9711.0 10345.0 11750.0 6167.2 True False 8199.01679724169 11341.408134959813 7948.777480564466 6681.037661377756 6370.915398775362 10296.23127377466 10575.260187300253 8746.417954450835 12371.081011899574 5951.288205149582 1.3776877399664789 1.9057064191826942 1.3356398155422013 1.12262041949115 1.0705103129206013 1.7300844655557848 1.7769699303336715 1.4696680202586492 2.078723225199381 1.0 12.538986270061498 -6.803298853754231 24.99991024097622 1.6508110916915468 1.3778022284510443 0.11666561097613537 0.33191627517768824 307.38048726495265 183576.04611606157 0.11771754830184149 0.10381801431609795 1.5729001224595345e-07 6.803298853754231 -0.27300886324050255 SS(ph)LEGPTILDIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSLEGPTILDIEK 13 0 A0A0G2JR96;A0A0G2JQT1;Q7L576;Q7L576-2 A0A0G2JR96 CYFIP1 Cytoplasmic FMR1-interacting protein 1 1 S(0.076)S(0.924)LEGPTILDIEK 126.63 0.0010145 0.0 6264.4 8025.1 6578.3 8656.9 8343.9 6357.5 11136.0 5838.9 8565.7 6937.2 True False 7324.83919246019 8821.778891961767 6735.151620341677 8171.881959048475 6708.972692187324 6024.101508260882 10081.117462341834 5685.635061825929 8690.95715778768 8194.85944515502 0.8938334136762767 1.0765015496607933 0.8218751847322587 0.9971961097978161 0.8186806298616648 0.7351073619477956 1.2301757619896716 0.6938050737633336 1.060537671933588 1.0 13.00050348968947 -9.778002148868774 10.952718049891942 0.9999866510125204 0.922249410112981 0.019206087425378104 0.15879890405260408 0.0 0.0 0.14283070439383447 0.03464153416453836 1.6672389631102812e-10 9.778002148868774 -0.07773724089953937 SS(ph)LGSHQLPR ddPTM_PC-9_AZD4547_30min_R2 2 SSLGSHQLPR 10 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 S(0.19)S(0.81)LGS(0.001)HQLPR;S(0.225)S(0.775)LGSHQLPR 152.96 9.766799999999999e-05 45668000.0 21963.0 31035.0 100760.0 162668.0 130190.0 133008.0 85104.0 148341.0 100858.0 125577.0 True False 28946.777141220577 41066.4568274971 99423.85656458556 125167.40579554728 112115.36574297948 124690.98873369941 92678.09113170649 125418.30698706527 106189.14797431207 121180.58745266375 0.23887305508011283 0.33888643132332325 0.8204602622794106 1.0328998103301066 0.9251924594504431 1.0289683467857995 0.7647932154802347 1.0349702838010824 0.8762884403064334 1.0 16.886799078949842 -5.281079388150351 2.9488288555647912 0.9476436378400286 0.2510372950007342 0.9140285852899542 0.0804132395128564 0.06251274378201516 1.0820745278890491 0.020583654538175362 0.05942370852099104 5.235047322355822e-06 5.281079388150351 -0.6966063428392943 down SS(ph)LGSHQLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSLGSHQLPR 10 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 S(0.219)S(0.535)LGS(0.246)HQLPR;S(0.301)S(0.699)LGSHQLPR 99.73200000000001 0.0024143 15047800.0 16213.9 32834.0 49545.0 44068.0 57024.0 45132.0 49470.0 49232.0 46896.0 37118.0 True False 18958.593030877717 36093.54252765356 50726.34070045882 41599.01283038368 45850.556550209134 42765.19846965473 44783.843468215724 47939.71216561583 47581.76528148438 43847.199574073675 0.43237865165938 0.8231664251824931 1.1568889505648772 0.9487267883575553 1.0456895080095383 0.9753233703650548 1.0213615442546045 1.093335780421471 1.0851722742544068 1.0 15.420197083345759 -4.855107269240217 2.817431859484512 1.0375347444079888 0.3716874028556237 0.9058294277172135 0.06000565381127961 0.09425761588592847 1.1628945982833145 0.015166471700292386 0.13549018246566846 1.3960235054742186e-05 4.855107269240217 -0.6658473415523651 down SS(ph)LGSHQLPR ddPTM_PC-9_Lapatinib_30min_R1 2 SSLGSHQLPR 10 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 S(0.145)S(0.855)LGSHQLPR;S(0.209)S(0.791)LGSHQLPR 120.55 0.00039477 37957000.0 105966.0 77808.0 168496.0 107338.0 123080.0 138587.0 91483.0 85311.0 144339.0 79734.0 True False 104454.90540821535 77627.8403565094 154642.9092933691 115231.99458907131 115840.67638459036 132659.95707207578 96219.54211024314 89274.86050311745 128082.0218629473 93515.91566112339 1.11697463121392 0.8301029809493807 1.6536533722639635 1.2322180002668335 1.2387268580501947 1.418581597947454 1.0289108696632665 0.9546488410232288 1.369628056972486 1.0 16.512924300606805 -7.292899505884781 24.93648952121887 1.0845176677508408 1.2466124873645663 0.11055123158841862 0.2223061893831208 1626.8082291795818 1289462.8090723096 0.09477296120656258 0.06390251538550606 5.0944874194851575e-08 7.292899505884781 0.16209481961372552 SS(ph)LGSLQTPEAVTTR ddPTM_PC-9_AZD4547_30min_R2 3 SSLGSLQTPEAVTTR 15 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 S(0.384)S(0.615)LGSLQTPEAVTTR;S(0.227)S(0.773)LGSLQTPEAVTTR;S(0.216)S(0.784)LGSLQTPEAVTTR 213.71 1.3196e-17 33722000.0 58863.0 60429.0 76902.0 123672.0 123392.0 103612.0 85944.0 124519.0 87810.0 99109.0 True False 77580.20957354041 79961.49249649816 75882.22923312579 95161.33111335292 106261.15070095823 97133.12526070635 93592.84950441071 105277.44971196335 92451.45733233204 95639.2240764318 0.8111756480953966 0.8360742495421701 0.793421631824231 0.9950031698009495 1.1110624508626055 1.0156201725672793 0.9786031872196528 1.1007769116552952 0.9666688351470502 1.0 16.54531480502324 -5.825104667284765 5.0110043691653035 1.0320508884902964 0.8155328744529469 0.8178908439400068 0.04560257135965191 0.07450705185568361 3.6365943914204193 0.012521721845201651 0.019300066803963827 1.4958750987768044e-06 5.825104667284765 -0.2165180140373495 SS(ph)LGSLQTPEAVTTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSLGSLQTPEAVTTR 15 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 S(0.241)S(0.759)LGSLQTPEAVTTR 112.12 0.00035141 8203800.0 10813.0 15074.0 10200.0 12898.0 16301.0 7800.9 10618.0 11610.0 7868.4 11349.0 True False 12643.427333515123 16570.44709940458 10443.206683715414 12175.366875880194 13106.936067707611 7391.807071300398 9612.186172337068 11305.249801811831 7983.460464449677 13406.483861365426 0.9430830234279947 1.2360024649831571 0.7789668634749538 0.9081700318878506 0.9776564983961942 0.5513606063855401 0.7169804008072019 0.8432673263711676 0.5954924905743761 1.0 13.71064328860933 -5.745604168929109 0.9475221300566752 0.7476060953489885 1.0871698977615674 0.2936797096217264 0.16303605085080372 0.8106177216778574 1.3422655423854 0.0648268491374542 0.20796391031453348 1.7963701550599112e-06 5.745604168929109 0.3395638024125789 SS(ph)LGSLQTPEAVTTR ddPTM_PC-9_Lapatinib_30min_R1 3 SSLGSLQTPEAVTTR 15 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 S(0.044)S(0.956)LGSLQTPEAVTTR;S(0.169)S(0.83)LGSLQTPEAVTTR;S(0.319)S(0.681)LGSLQTPEAVTTR 140.77 7.4219e-05 41323000.0 116061.0 131123.0 106126.0 102919.0 90371.0 92645.0 79184.0 76133.0 84759.0 83760.0 True False 114405.94885701944 130819.39274967289 97400.72993820696 110488.00658771963 85055.5554562221 88682.78931604327 83283.76006971237 79670.41711718088 75212.54886816142 98237.8043968155 1.164581696012824 1.3316603883088571 0.9914791004975304 1.124699470495304 0.8658128709051164 0.9027358648797126 0.847777091325263 0.8109954981828106 0.7656171606233448 1.0 16.583990696556164 -5.8837432219344405 0.9335012931280157 0.8399081462570969 1.2572113121264146 0.700969919860044 0.09315758351278834 0.33203627852050244 0.5644127429655874 0.037608765677182784 0.09871993887918776 1.3069433943908024e-06 5.8837432219344405 0.4173031658693177 SS(ph)LPNGEGLQLK ddPTM_PC-9_AZD4547_30min_R2 1 SSLPNGEGLQLK 12 0 Q9ULR3 Q9ULR3 PPM1H Protein phosphatase 1H 1 S(0.136)S(0.864)LPNGEGLQLK 111.88 0.0010206 7748500.0 53275.0 61448.0 63331.0 62676.0 55782.0 66406.0 68590.0 72401.0 71281.0 62002.0 True False 70215.34181116102 81309.86431886724 62491.18956025973 48227.0165345471 48037.63216740838 62253.622322341755 74694.37712356348 61213.08905946788 75048.76813695439 59831.32885194002 1.1735547773795483 1.3589847639867485 1.0444559858414955 0.8060495639983324 0.8028842596206313 1.0404853697365806 1.2484158142033566 1.0230942590452434 1.2543389822190276 1.0 15.868613485109828 -5.331847623224037 7.1269457136879355 1.0198799419268307 1.2654228072100948 0.29403488555926727 0.14779709144016 0.3131708395443576 27.390936119052984 0.042482821143812084 0.08947233035117562 4.6574947795009155e-06 5.331847623224037 0.24554286528326408 SS(ph)LPNGEGLQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSLPNGEGLQLK 12 0 Q9ULR3 Q9ULR3 PPM1H Protein phosphatase 1H 1 S(0.162)S(0.838)LPNGEGLQLK 78.324 0.016599000000000003 5929100.0 43453.0 68924.0 49816.0 50746.0 49642.0 38666.0 60453.0 42080.0 35293.0 40787.0 True False 50808.734664129515 75766.31921715269 51003.80236823206 47902.866140751794 39915.006458078715 36638.28689239722 54726.454198181644 40975.44458744542 35809.09335720378 48181.36023028568 1.0545309310755475 1.5725234583461956 1.0585795445470272 0.9942198790527539 0.8284325363024739 0.7604245026973574 1.1358428640580776 0.8504418387442952 0.743214661978244 1.0 15.556187503092348 -5.56708309109301 3.0413985759227904 0.8950777364826437 1.3169336067846091 0.49320898482324305 0.16355146067981413 0.18790556227648883 3.524329507395697 0.04423488410694073 0.0903597762747653 2.7096731559412533e-06 5.56708309109301 0.4218558703019655 SS(ph)LPNGEGLQLK ddPTM_PC-9_Lapatinib_30min_R1 1 SSLPNGEGLQLK 12 0 Q9ULR3 Q9ULR3 PPM1H Protein phosphatase 1H 1 S(0.146)S(0.854)LPNGEGLQLK 139.48 7.2537e-05 6396500.0 39911.0 64955.0 56063.0 48767.0 73391.0 62101.0 68888.0 61447.0 61025.0 49643.0 True False 39341.861821219005 64804.60068832331 51453.71654943832 52353.48786194302 69074.28567225765 59445.08499450159 72454.68356842727 64302.05194330209 54151.721878261305 58223.726404860485 0.6757015438629632 1.1130273634102792 0.8837242087813705 0.8991778969607925 1.1863597529286853 1.0209769910834692 1.244418522177907 1.1043960239881552 0.9300627977968231 1.0 15.829319556587778 -6.2430491352164 24.065013987393368 1.0914216883280985 0.9079745814469903 0.33090218230034485 0.1298497413515433 611.1091698049206 799681.3689366351 0.03702070841239116 0.04768249834837502 5.714139843696426e-07 6.2430491352164 -0.1834471068811082 SS(ph)LPRPSSILPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSLPRPSSILPPR 13 1 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4;H7BZB9 A0A669KB77 MAP2 Microtubule-associated protein 2 1 S(0.234)S(0.764)LPRPS(0.001)SILPPR 76.165 0.0082788 3594000.0 5694.9 6206.3 5316.0 8473.6 5813.2 9513.6 9273.5 6379.3 6766.5 5569.2 True False 6658.934090597912 6822.420447992215 5442.753601042266 7998.851663781861 4674.14519040537 9014.690068264368 8395.046945674121 6211.850134427062 6865.447261539668 6578.851874237058 1.0121726735746184 1.0370229606033503 0.8273105558670838 1.2158431009984518 0.7104803816467483 1.3702527797541864 1.2760656579834737 0.9442149258220597 1.043563131193898 1.0 12.683620114842784 -6.766549084671754 24.999995193102635 1.1326605590968444 0.9715925477217585 0.18927314582205756 0.17106936383994725 236.35172772064047 1156377.830467643 0.05933360158183431 0.05391527663859642 1.7117916962756444e-07 6.766549084671754 -0.16106801137508586 SS(ph)LPRPSSILPPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSLPRPSSILPPR 13 1 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4;H7BZB9 A0A669KB77 MAP2 Microtubule-associated protein 2 1 S(0.232)S(0.745)LPRPS(0.012)S(0.012)ILPPR 71.031 0.012662999999999999 7076600.0 21131.0 17535.0 18033.0 13306.0 14677.0 14868.0 12736.0 13630.0 15277.0 10572.0 True False 20829.668065049205 17494.39878484719 16550.39634939301 14284.567627514783 13813.727716092235 14232.130299000813 13395.407762273406 14263.299558761335 13556.343386058146 12399.356113695487 1.6798991717031313 1.4109118751355214 1.3347786931542813 1.1520410815314046 1.1140681491383677 1.1478120451174856 1.080330917141556 1.150325825629531 1.0933102704490218 1.0 13.597977584379564 -1.5228787456144943 0.4733524739848266 1.076453233079842 17.500458585710867 0.9524700304229412 0.04198440265096102 18.278762166215653 0.20833061386332355 0.0244324634117803 294.28060763887595 0.02999999997691727 1.5228787456144943 16.424005352631024 SS(ph)LSASHPMVGK ddPTM_PC-9_AZD4547_30min_R2 3 SSLSASHPMVGK 12 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q8TEW0-6;Q8TEW0-7;Q8TEW0-8;Q5VWU8;Q8TEW0-9;Q8TEW0-10 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.229)S(0.768)LS(0.003)ASHPMVGK;S(0.189)S(0.811)LSASHPMVGK;S(0.038)S(0.928)LS(0.029)AS(0.004)HPMVGK 122.34 0.0017324999999999999 30306000.0 61866.0 52149.0 127827.0 232561.0 170595.0 153335.0 98054.0 171021.0 120606.0 161142.0 True False 81538.10110726011 69005.14442072331 126131.93045932206 178947.6544816327 146910.82893404728 143746.93821034662 106780.6160442322 144593.6341216175 126980.98693797106 155500.46762780764 0.524359201944155 0.44376165212498275 0.811135377169543 1.1507853140991589 0.9447613320731628 0.9244148291206864 0.6866899995427215 0.9298598025293675 0.8165955310301811 1.0 17.24655939333484 -5.355022707554813 4.369060104719845 0.914169432761899 0.48428345944925705 0.6912827477433255 0.11482351938895151 0.12229043202241288 4.017735615035716 0.032068184940113466 0.07156179028833984 4.415473599703879e-06 5.355022707554813 -0.42988597331264194 SS(ph)LSASHPMVGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSLSASHPMVGK 12 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q8TEW0-6;Q8TEW0-7;Q8TEW0-8;Q5VWU8;Q8TEW0-9;Q8TEW0-10 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.083)S(0.917)LSASHPMVGK;S(0.224)S(0.753)LS(0.02)AS(0.003)HPMVGK 113.95 0.00069688 27301300.0 39321.0 45377.0 80681.0 75564.0 89715.0 84660.0 77371.0 74804.0 75299.0 49806.0 True False 45977.268674849525 49881.728673854406 82604.74102439621 71330.3940617933 72135.98977451632 80220.28056458767 70041.85876246844 72840.47426138948 76400.10542328753 58835.43353592094 0.7814554242517633 0.8478178144705943 1.403996470493641 1.212371351325962 1.2260637075186156 1.363468844257102 1.1904706832780558 1.23803752065357 1.2985390067134082 1.0 15.844397656891065 -5.194878266941362 6.816675476070953 1.2507404377596927 0.8070124226638041 0.72754445195426 0.10445499966236291 0.11405775546333008 9.766351182446861 0.024621073822366557 0.06625845423874674 6.384424169852443e-06 5.194878266941362 -0.44372801509588855 SS(ph)LSASHPMVGK ddPTM_PC-9_Lapatinib_30min_R1 3 SSLSASHPMVGK 12 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q8TEW0-6;Q8TEW0-7;Q8TEW0-8;Q5VWU8;Q8TEW0-9;Q8TEW0-10 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.031)S(0.969)LSASHPMVGK;S(0.03)S(0.968)LS(0.002)ASHPMVGK;S(0.08)S(0.919)LSASHPMVGK 126.5 0.00023052 19375000.0 101048.0 84917.0 157884.0 119889.0 143852.0 151486.0 110412.0 106751.0 162659.0 77400.0 True False 99607.03699006609 84720.37990378501 144903.38696986483 128706.03699798018 135390.9081839137 145007.29691111352 116128.59310993498 111711.04117368517 144338.630544795 90778.48687098271 1.0972537703964023 0.933264948821986 1.5962304722682386 1.4178032861563479 1.4914426628011062 1.5973751260824882 1.2792523549657824 1.2305893722645154 1.5900092138562927 1.0 16.470062820657127 -5.25261902378981 24.91454946991592 1.4151632251499853 1.0152593234072955 0.408689776306564 0.18458850704424778 547.4807898558157 1546441.0319517313 0.04508563025252433 0.11543320408495175 5.589603165686599e-06 5.25261902378981 -0.39990390174268975 SS(ph)LSGDEEDELFK ddPTM_PC-9_AZD4547_30min_R2 2 SSLSGDEEDELFK 13 0 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 1 S(0.12)S(0.873)LS(0.007)GDEEDELFK;S(0.028)S(0.969)LS(0.003)GDEEDELFK 174.94 0.00010644 2043740.0 16427.3 15683.3 16957.1 19226.5 20846.6 17540.2 17154.5 18538.699999999997 16382.2 17537.0 True False 21650.839690933528 20752.620021352825 16732.237774427682 14794.127471463886 17952.40942850912 16443.408521192956 18681.217267330074 15673.969891945633 17248.129647075843 16923.034967847358 1.2793709717003294 1.2262942232750464 0.9887255924376344 0.8742006087898385 1.0608268234756653 0.9716583669793474 1.1038928479922865 0.9261914261670637 1.0192101877616009 1.0 14.046700703351124 -5.222148363781399 4.514750475392922 0.9912361106755697 1.2629628184861985 0.7443088650816327 0.06110739544329149 0.09570502174633343 4.59773722713288 0.015628048562963695 0.042897806330130565 5.995862104843926e-06 5.222148363781399 0.2717267078106288 SS(ph)LSGDEEDELFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSLSGDEEDELFK 13 0 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 1 S(0.36)S(0.635)LS(0.005)GDEEDELFK;S(0.047)S(0.953)LSGDEEDELFK 237.48 4.8518e-26 12497300.0 62827.0 66539.0 48820.0 62595.0 64783.0 57520.0 59249.0 54790.0 48324.0 48428.0 True False 73462.37021018722 73144.55217906882 49984.05395088105 59088.00508572805 52089.23619865663 54503.549941827136 53636.50579438676 53351.820554803606 49030.64707997381 57207.613044162936 1.284136259163199 1.2785807392908168 0.873730807686287 1.0328696119538059 0.9105297953691052 0.9527324606211357 0.9375763633588529 0.9326000110093259 0.8570650735265479 1.0 15.803919529528859 -5.254594501460833 24.996655053095633 0.9377721632019066 1.2813585526458189 0.8853942149011979 0.04953679874872358 147.27246689574926 537817.451871439 0.012028811405304787 0.03033816104746051 5.564235446258395e-06 5.254594501460833 0.3435863894439123 SS(ph)LVTSK ddPTM_PC-9_AZD4547_30min_R2 1 SSLVTSK 7 0 A6NMQ3;Q5T5H1;O43768-2;O43768;O43768-9;O43768-3;O43768-4;A0A1W2PRU0;O43768-6;O43768-5;O43768-7 A6NMQ3 ENSA Alpha-endosulfine 1 S(0.147)S(0.85)LVT(0.001)S(0.002)K 71.45100000000001 0.041382 58265000.0 210320.0 166870.0 178550.0 276630.0 297360.0 168330.0 183650.0 269130.0 217920.0 225530.0 True False 277197.3850722364 220807.4641792956 176182.31033750245 212857.2273908957 256076.69680722436 157804.29848989233 199994.49422280875 227542.14249215604 229438.80630750256 217634.2633459889 1.273684487040332 1.014580428580136 0.809533883262732 0.9780501659911023 1.176637781524873 0.7250894048747253 0.9189476470663218 1.0455253644065037 1.0542402780703106 1.0 17.731546180234616 -4.78566261422955 4.1733591140476936 0.9603745354259123 1.2973478377585557 0.3706929123278818 0.1203694734273469 0.22762225571548844 7.783461721034323 0.030797685707175806 0.22543339041542676 1.638088591849222e-05 4.78566261422955 0.33697330233264333 SS(ph)LVTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSLVTSK 7 0 A6NMQ3;Q5T5H1;O43768-2;O43768;O43768-9;O43768-3;O43768-4;A0A1W2PRU0;O43768-6;O43768-5;O43768-7 A6NMQ3 ENSA Alpha-endosulfine 1 S(0.034)S(0.965)LVTSK 76.17 0.031649000000000004 90182000.0 346010.0 302120.0 244030.0 226120.0 261290.0 187540.0 123440.0 247210.0 132530.0 111620.0 True False 404582.6589909894 332112.4769584788 249848.60068892824 213451.22949093155 210092.1001859597 177705.07225469855 111746.869571792 240720.99944064565 134468.00052787282 131855.8224165662 3.0683715862983245 2.5187547343131405 1.8948621009665598 1.6188229353769805 1.5933471600687084 1.3477226033544645 0.8474928715605378 1.825637996327129 1.019810866622591 1.0 17.008601752776507 -2.9948146252168346 0.4341662938864426 1.1612314848419294 12.078596691146762 0.8583187781096648 0.24999156866673033 7.842684334283984 0.33237594887635175 0.16411753270369725 61.37426150373197 0.0010120113302251998 2.9948146252168346 10.917365206304833 up SS(ph)LYGIAK ddPTM_PC-9_AZD4547_30min_R2 1 SSLYGIAK 8 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 S(0.222)S(0.773)LY(0.005)GIAK 93.598 0.007104899999999999 7209000.0 43924.0 47024.0 53368.0 66924.0 80723.0 66296.0 45769.0 84160.0 58308.0 64843.0 True False 57890.918324043785 62223.5883955606 52660.305449968284 51495.70576549288 69516.00483040586 62150.5006397309 49842.35233369844 71155.00580440606 61390.04184185874 62572.8663066731 0.9251760665767997 0.9944180611864466 0.8415837176433183 0.8229718215737403 1.110960851460824 0.9932500188680479 0.7965489720323551 1.1371543290932433 0.981096847010056 1.0 15.933249571355756 -6.248514120650552 24.979808634987677 0.9991993236867782 0.8991750626219586 0.229890650474451 0.09582489923222125 1354.3718645672993 2617506.5013269195 0.029190746276741418 0.03744964972399027 5.642685944180627e-07 6.248514120650552 -0.10002426106481965 SS(ph)LYGIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSLYGIAK 8 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 S(0.181)S(0.819)LYGIAK 117.31 0.0035521999999999997 8188300.0 105640.0 101940.0 92257.0 88614.0 114780.0 79916.0 62385.0 84217.0 51020.0 48171.0 True False 123522.76551489304 112059.92950201039 94456.7567666208 83649.24487046436 92289.68295512424 75725.06427592236 56475.44117171293 82006.39298528718 51766.07097964292 56904.02097857382 2.170721214260119 1.9692796321758093 1.6599311462047084 1.4700058700941534 1.6218481816930697 1.3307506740944592 0.9924683739480861 1.4411352936933086 0.9097084896537364 1.0 15.796242980075771 -1.5228787452818755 0.22796616835529226 0.9335005197089963 8.15980196836976 0.856127319451203 0.15080478830649047 17.30091111384278 0.22542558135491833 0.2174163916251287 46.51586858746202 0.029999999999893764 1.5228787452818755 7.226301448660763 up SS(ph)LYGIAK ddPTM_PC-9_Lapatinib_30min_R1 1 SSLYGIAK 8 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 S(0.159)S(0.835)LY(0.005)GIAK 114.4 0.0036791 7263100.0 85005.0 79039.0 89473.0 90120.0 62219.0 62402.0 53619.0 54333.0 80115.0 83757.0 True False 83792.81311199199 78855.9900516417 82116.8753157679 96747.72543150726 58559.400747260486 59733.21192616684 56395.1294602181 56857.50953236825 71091.60505164936 98234.2858508128 0.8529894871862468 0.8027338863276241 0.835928867447337 0.9848671937050252 0.5961197787521347 0.6080688774679234 0.5740880485033982 0.5787949598240786 0.7236944253823487 1.0 16.58393902317229 -6.273199627300048 24.88988220930397 0.6501625022765757 0.8620157929128643 0.32997044741310244 0.1275677042212996 699.9777456111227 1481459.4047830778 0.0376082514391788 0.042990102704113665 5.33089799719966e-07 6.273199627300048 0.21185329063628866 SS(ph)MEMEGIFNHK ddPTM_PC-9_Lapatinib_30min_R1 5 SSMEMEGIFNHK 12 0 E7EPJ7;O75962-4;O75962;O75962-5;O75962-2;E7EWP2 E7EPJ7 TRIO Triple functional domain protein 1 S(0.144)S(0.856)MEMEGIFNHK;S(0.133)S(0.867)MEMEGIFNHK;S(0.215)S(0.785)MEMEGIFNHK;S(0.258)S(0.742)MEMEGIFNHK;S(0.228)S(0.772)MEMEGIFNHK 145.61 6.3659e-05 16756600.0 146797.0 166686.0 153909.0 134368.0 164198.0 174445.0 153335.0 149462.0 174495.0 120544.0 True False 144703.64786072727 166300.04880815695 141255.1961259206 144249.87095850834 154540.1964656887 166984.3940011564 161273.93602608304 156406.5501578568 154841.53558618933 141379.86978521635 1.0235095567746695 1.1762639834143236 0.9991181654114892 1.0202999279717266 1.0930848691575785 1.1811044546500031 1.1407135702635012 1.1062858552315045 1.0952162837709774 1.0 17.109217192685385 -6.516116081250631 24.731725219482737 1.116174955381608 1.0591463605953422 0.11151027398508317 0.06241042611383912 523.4991875104735 1914498.4356417474 0.020068981477267732 0.020815743838048878 3.047080435914738e-07 6.516116081250631 -0.057028594786265874 SS(ph)MGSTAVATDVK ddPTM_PC-9_AZD4547_30min_R2 1 SSMGSTAVATDVK 13 0 Q6UXY1;B0QYF0;Q6UXY1-2 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 S(0.313)S(0.657)MGS(0.028)T(0.003)AVATDVK 94.53200000000001 0.0032972 10617000.0 66639.0 75728.0 79468.0 75842.0 90798.0 102210.0 86531.0 102010.0 98185.0 90027.0 True False 87828.8158226927 100205.59505824724 78414.20239653115 58357.7986472194 78192.2649875649 95818.79254233872 94232.09136724111 86246.6984566004 103374.85865134979 86875.1821320862 1.0109770554397985 1.1534432803363024 0.9026076316859876 0.6717430365612519 0.9000529618306907 1.102947817670811 1.084683669773139 0.9927656707006351 1.1899239358621112 1.0 16.4066564768575 -6.7605000179702515 24.999986463708822 1.0742758006024928 0.9246814230247321 0.26106910589479204 0.12301068118227591 40.13893348443658 1068264.817983219 0.04641746450330676 0.04388712369841291 1.7358011910474095e-07 6.7605000179702515 -0.14959437757776073 SS(ph)MGSTAVATDVK ddPTM_PC-9_Lapatinib_30min_R1 3 SSMGSTAVATDVK 13 0 Q6UXY1;B0QYF0;Q6UXY1-2 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 S(0.196)S(0.804)MGSTAVATDVK;S(0.021)S(0.979)MGSTAVATDVK;S(0.024)S(0.975)MGS(0.001)T(0.001)AVATDVK 175.29 0.00011853 7994300.0 54409.0 88717.0 85106.0 83483.0 95961.0 81931.0 97344.0 95206.0 94535.0 74510.0 True False 53633.117682611424 88511.58123725609 78108.91319866039 89622.61831112391 90316.76264658479 78427.0021204893 102383.99601214999 99629.61832659047 83887.47280231756 87388.95422166592 0.6137287962797754 1.0128463262386982 0.8938076201316439 1.0255600276871628 1.0335031864266546 0.8974475414999905 1.1715896697018309 1.1400710674929875 0.9599322196891532 1.0 16.4151633172078 -4.414780848189721 1.740402319188388 1.0256511035037392 4.054561346335892e-30 0.6492057749855469 0.08730489799307874 1.9262979214219216 2.5275072980485027 0.024530368546472767 4.493092138412618 3.847859020672625e-05 4.414780848189721 -1.0256511035037392 SS(ph)MSGLHLVK ddPTM_PC-9_AZD4547_30min_R2 1 SSMSGLHLVK 10 0 A0A0C4DGT1;Q13085;Q13085-2;Q13085-4 A0A0C4DGT1 ACACA Acetyl-CoA carboxylase 1;Biotin carboxylase 1 S(0.13)S(0.812)MS(0.058)GLHLVK 68.44 0.023226 6604900.0 35959.0 46667.0 110540.0 154510.0 137360.0 113720.0 103360.0 128330.0 103200.0 95569.0 True False 47393.214006335715 61751.19512707609 109074.16737444718 118890.1066557036 118289.93500618848 106609.07042280387 112558.83976514803 108499.54723003166 108654.94131302422 92223.15839893969 0.5138971038198644 0.6695844753001439 1.1827199292244281 1.289156744571768 1.2826489252784958 1.1559902336204262 1.2205051498913113 1.1764891716317438 1.1781741506076358 1.0 16.49284145462981 -5.203535125298583 3.470389888893323 1.2024343783797244 0.5454850301836743 0.9035440207568177 0.07816532293028376 0.06113764264440049 1.4661590282428223 0.02000991367739261 0.0611119787851309 6.258422443865009e-06 5.203535125298583 -0.6569493481960501 SS(ph)MSLYTAASVIDTASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSMSLYTAASVIDTASK 17 0 Q96PE2;A0A2R8Y4D7 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 S(0.229)S(0.736)MS(0.035)LYTAASVIDTASK 92.236 0.0018320999999999997 3764200.0 24445.0 22945.0 17952.0 14890.0 20998.0 17382.0 13006.0 15942.0 13661.0 10842.0 True False 28583.05568924231 25222.82796177776 18380.043763339134 14055.76157403133 16883.592635404235 16470.457320737813 11773.977524714244 15523.539391945229 13860.766280927133 12807.56877477522 2.2317315793405887 1.96936892593188 1.435092333803354 1.097457434834506 1.318251178838628 1.2859940563564827 0.9192984032928516 1.2120598112671603 1.0822324302662507 1.0 13.644709018424553 -5.242365565234353 1.657666974838225 1.1371419923215906 2.2861839555309715 0.9163527949817822 0.11696929913648124 0.12587841614638373 0.5750732979216563 0.03465286586145736 0.17255800482742842 5.723140856228732e-06 5.242365565234353 1.149041963209381 up SS(ph)MSLYTAASVIDTASK ddPTM_PC-9_Lapatinib_30min_R1 1 SSMSLYTAASVIDTASK 17 0 Q96PE2;A0A2R8Y4D7 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 S(0.204)S(0.751)MS(0.042)LY(0.002)TAASVIDTASK 100.58 0.0085804 0.0 6027.6 7681.0 6762.9 6180.9 5510.7 6076.0 3736.3 3432.8 6665.0 5477.9 True False 5941.645318673537 7663.215116419235 6206.880467548939 6635.464004877965 5186.571460453051 5816.14364384779 3929.7473321436955 3592.3004200525247 5914.317514438539 6424.74771615706 0.9248060128075366 1.1927651411350608 0.9660893690719988 1.0327975973579464 0.8072801749724393 0.9052719111789025 0.611657843351748 0.5591348608161764 0.9205524910441413 1.0 12.649424089039407 -6.389159937973759 1.4619163797535553 0.7507884901193759 1.0508731224459573 0.35286956746007625 0.14526240609221822 0.3824077181308835 1.6502901337565175 0.05602292076433342 0.06939365861627272 4.08169041913436e-07 6.389159937973759 0.30008463232658145 SS(ph)PAELSSSSQHLLR ddPTM_PC-9_AZD4547_30min_R2 1 SSPAELSSSSQHLLR 15 0 Q9UQC2-2;Q9UQC2;E9PJE2 Q9UQC2-2 GAB2 GRB2-associated-binding protein 2 1 S(0.175)S(0.825)PAELSSSSQHLLR 163.41 0.00018896 7143700.0 2520.6 2896.6 25625.0 57782.0 40459.0 28096.0 14314.0 38890.0 18930.0 36056.0 True False 3322.0983682630144 3832.869303899727 25285.19575692243 44461.25262300088 34841.96622317551 26339.152678500664 15587.91827010771 32880.44410329557 19930.60115363905 34793.690414592245 0.09547990824421856 0.11015989560832118 0.7267178461275836 1.277853889403871 1.0013874874440745 0.7570094567334024 0.4480099145668733 0.9450116877945701 0.5728222823204833 1.0 15.086538086977123 -5.296300535186883 4.399922469554097 0.8494812897622381 0.09163456609654017 0.6439113385020963 0.2209796159776185 0.12485004839297312 5.739982689967656 0.06235016146812006 0.14748632989575233 5.054747484561399e-06 5.296300535186883 -0.7578467236656979 SS(ph)PAPHSGPCPSR ddPTM_PC-9_AZD4547_30min_R2 2 SSPAPHSGPCPSR 13 0 P85299;P85299-5;P85299-2;P85299-4;P85299-3 P85299 PRR5 Proline-rich protein 5 1 S(0.14)S(0.848)PAPHS(0.001)GPCPS(0.011)R;S(0.229)S(0.771)PAPHSGPCPSR 97.073 0.0017587 6920900.0 6165.6 5628.4 13450.599999999999 20969.7 17303.7 12298.4 10260.099999999999 15877.2 9075.1 13089.3 True False 8126.132547553148 7447.670230639108 13272.236255534077 16135.459643635404 14901.379938603563 11529.379103832316 11173.229023552607 13423.743561759951 9554.79125881616 12631.047591072851 0.6433458894808054 0.5896320298803118 1.0507629046473068 1.2774442917180788 1.1797422051624045 0.9127809091607609 0.884584508370424 1.0627577376279818 0.7564527953777268 1.0 13.624686677564048 -5.261504784138571 24.99999990942274 1.0246744970194497 0.6164889256161111 0.5643329098575363 0.1400746926979641 4.148622894220506 1586524.4531337724 0.039286612257454084 0.0911537445119898 5.476400681880197e-06 5.261504784138571 -0.40818557140333855 SS(ph)PAPHSGPCPSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPAPHSGPCPSR 13 0 P85299;P85299-5;P85299-2;P85299-4;P85299-3 P85299 PRR5 Proline-rich protein 5 1 S(0.215)S(0.785)PAPHSGPCPSR 132.65 3.0359000000000002e-05 2529900.0 9374.8 6126.6 10633.0 10712.0 8537.0 9222.8 7593.8 6172.9 13136.0 5841.3 True False 9241.113632872235 6112.414234117182 9758.79578456696 11499.796214184465 8034.87044438777 8828.362343396873 7986.969807251236 6459.715469279368 11656.48535178764 6850.9609219569975 1.34887846218111 0.8921980877933766 1.4244418988423206 1.678566896700312 1.1728092651406608 1.2886312509975644 1.1658174522136573 0.9428918866806397 1.7014380149840251 1.0 12.742090640635169 SS(ph)PELEDTATSSK ddPTM_PC-9_AZD4547_30min_R2 2 SSPELEDTATSSK 13 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(0.166)S(0.834)PELEDTATSSK;S(0.194)S(0.806)PELEDTATSSK 130.61 7.8388e-05 15065900.0 42351.0 109291.0 60558.0 57400.0 59090.0 55285.0 57535.0 60513.0 45514.0 52464.0 True False 55817.73704447634 144617.17844800974 59754.961352105725 44167.31682115971 50886.37346764477 51828.0202103826 62655.50353993617 51162.106300404375 47919.77712132743 50627.251328798804 1.102523553608864 2.8565085927496465 1.180292427175771 0.8724020297747346 1.0051182343904688 1.0237178367394548 1.2375845398562102 1.0105645666625658 0.9465214062306548 1.0 15.627626538654827 -5.49348241684305 24.26403509234119 1.0237463126942148 1.9892377092946696 0.4736000902024622 0.4017587580425574 349.1833017901724 288218.53733604914 0.09516920303977566 0.19750739860095506 3.210092767691044e-06 5.49348241684305 0.9654913966004548 SS(ph)PELEDTATSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPELEDTATSSK 13 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 S(0.232)S(0.766)PELEDT(0.001)ATSSK 116.9 0.0002669 7201600.0 47883.0 93996.0 59881.0 61424.0 69271.0 40312.0 71189.0 46803.0 49118.0 32687.0 True False 55988.64616764122 103327.30168207739 61308.790139957135 57982.612419294855 55697.84481603427 38197.96775477982 64445.46255627273 45574.47084187759 49836.25782787341 38612.89434985035 1.449998688530279 2.6759791883479425 1.587780226586271 1.5016385949715674 1.4424674905586334 0.9892541959866799 1.669014033819055 1.1802914961243827 1.2906636155356366 1.0 15.236795079586066 -5.491127562757655 5.868356088342168 1.3270082895674145 2.0851016744277917 0.44184157186507067 0.3405149022510383 0.1527292614216032 15.769864022410166 0.08481460127258844 0.17145255333866055 3.2275459744224997e-06 5.491127562757655 0.7580933848603773 SS(ph)PELTR ddPTM_PC-9_AZD4547_30min_R2 1 SSPELTR 7 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.223)S(0.777)PELTR 106.68 0.010019 74727000.0 23164.0 26006.0 23742.0 32489.0 27995.0 30283.0 30603.0 30768.0 28781.0 23554.0 True False 30529.67015886871 34411.93092495212 23427.165567252792 24999.16300004629 24108.377478874867 28389.399222773198 33326.60771413343 26013.512578302878 30302.304902423963 22729.381629279633 1.3431808509713643 1.5139844755223437 1.0306996445989665 1.099861114032366 1.0606701876930447 1.2490176673439466 1.4662346850299974 1.1444883544386741 1.3331777078963296 1.0 14.472270814584796 -11.786313452206105 2.1744166702925902 0.08831041341619006 1.2437911846559495 0.1819143286034416 0.1580820465857113 2660291.212564415 526805.7896489557 11888209.929434856 0.042812788842667704 1.6356355747117865e-12 11.786313452206105 1.1554807712397595 SS(ph)PELTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPELTR 7 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.202)S(0.798)PELTR;S(0.206)S(0.785)PELT(0.009)R 105.1 0.010251999999999999 159821000.0 103840.0 129896.0 129217.0 123601.0 141256.0 114600.0 115719.0 108343.0 100806.0 88887.0 True False 121418.06106651324 142791.21642724256 132298.02333820148 116676.03668984893 113577.90081468057 108590.17425823006 104757.258586991 105499.11104889718 102280.09704378434 105001.50947089537 1.1563458628198888 1.3598967971676812 1.2599630615298179 1.1111843751369073 1.081678743353327 1.0341772685499289 0.9976738345464254 1.004738994520262 0.9740821590011012 1.0 16.680050542237943 -6.0861324519356605 1.3607202209142069 1.0017303835410745 1.2755058023533503 0.816734828165808 0.051808730194356535 0.16617530237055667 0.6224542235599322 0.018820062591449783 0.03133280348425946 8.201013901442358e-07 6.0861324519356605 0.27377541881227585 SS(ph)PELTR ddPTM_PC-9_Lapatinib_30min_R1 2 SSPELTR 7 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.08)S(0.92)PELTR;S(0.221)S(0.772)PELT(0.007)R 138.06 0.0031853000000000003 136193000.0 155883.0 182069.0 200648.0 169241.0 166823.0 141283.0 115571.0 125905.0 139708.0 105650.0 True False 153660.07983455877 181647.43041678588 184151.4959636784 181687.547711426 157010.7991266371 135240.65543675906 121554.70088675409 131755.00593880002 123972.6138495393 123911.46173022417 1.2400796317704836 1.4659453442028028 1.4861538504372322 1.466269101941433 1.2671208694840168 1.091429747888863 0.9809802837400051 1.063299585841805 1.0004935146310214 1.0 16.91895011644766 -6.661866160385327 2.276320818831098 1.01788474889641 1.4225599170550287 0.8770853866510113 0.06901292352541319 0.0981875635077216 1.0400311046028798 0.026360024009997377 0.025916791897186642 2.1783809960615002e-07 6.661866160385327 0.4046751681586187 SS(ph)PEQPIGQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPEQPIGQGR 11 0 Q8N201 Q8N201 INTS1 Integrator complex subunit 1 1 S(0.179)S(0.821)PEQPIGQGR 84.352 0.012055 24410000.0 21086.0 27510.0 29868.0 18980.0 25791.0 25206.0 26697.0 18377.0 19858.0 20333.0 True False 24655.443332516395 30241.01099274379 30580.16639502077 17916.612133990242 20737.438692242617 23884.152987372992 24168.06689045797 17894.623222040984 20148.385682354954 24019.211944060557 1.0264884372533782 1.2590342706985336 1.2731544426286892 0.7459283916440331 0.8633688207814223 0.9943770446340159 1.0061973284862171 0.745012919812548 0.8388445769694465 1.0 14.551901197410379 -5.754949866669059 24.999894142453595 0.8829226348829335 1.1935066164404493 0.613700673866803 0.10953102189926034 102.11017460373229 393359.62161367806 0.030965508999181476 0.052050556023542936 1.7581265537999921e-06 5.754949866669059 0.31058398155751576 SS(ph)PEQPRPSTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SSPEQPRPSTSK 12 1 P29590;P29590-5;P29590-9;P29590-3;P29590-8;P29590-4;P29590-11;P29590-12;P29590-13;H3BVD2;H3BT57;H3BUJ5;H3BRN3;P29590-2 P29590;P29590-2 PML Protein PML 1 S(0.228)S(0.772)PEQPRPSTSK;S(0.234)S(0.766)PEQPRPSTSK;S(0.195)S(0.713)PEQPRPS(0.083)T(0.007)S(0.002)K;S(0.192)S(0.805)PEQPRPS(0.002)TSK;S(0.236)S(0.764)PEQPRPSTSK 123.26 0.0017530000000000002 134901200.0 64399.2 65636.0 69093.3 79800.3 88670.6 76178.9 86636.90000000001 75527.4 71211.1 61190.399999999994 True False 75300.7126178218 72151.90830678772 70740.74630979954 75329.34790706316 71296.23245722805 72183.94437871086 78430.02563516187 73544.88577789528 72252.42761933475 72283.73513706021 1.0417379853855224 0.9981762587389469 0.9786537203101784 1.042134136596954 0.9863385216887351 0.9986194576392582 1.0850300622463327 1.0174472256925262 0.9995668801886607 1.0 16.141383436450447 SS(ph)PGAVAGLSNAPGTPR ddPTM_PC-9_AZD4547_30min_R2 1 SSPGAVAGLSNAPGTPR 17 0 U3KPY3;V9GYB2;Q9BWG4-2;Q9BWG4 U3KPY3 SSBP4 Single-stranded DNA-binding protein 4 1 S(0.248)S(0.752)PGAVAGLSNAPGTPR 95.073 0.001686 5681000.0 7725.8 6996.3 9520.8 10390.0 8228.2 9008.0 8952.4 9696.9 6717.1 10875.0 True False 10182.443693377134 9257.71715489666 9394.547971219785 7994.746023899809 7085.856459070478 8444.728335988539 9749.146256903183 8198.466917594425 7072.1521927685635 10494.269560092385 0.970286081853561 0.8821687971597292 0.8952074193848972 0.7618201512854439 0.6752119734008527 0.8046990109823514 0.9289971256291378 0.7812327356990677 0.6739060924890427 1.0 13.357314132772581 -5.656999532088698 5.1295055011390085 0.7947219767789602 0.9171589325064446 0.21692289499223905 0.09726236852215472 0.3106707960872152 12.815487301071343 0.02683988694279967 0.04723953167267411 2.2029288365000164e-06 5.656999532088698 0.12243695572748448 SS(ph)PGAVAGLSNAPGTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPGAVAGLSNAPGTPR 17 0 U3KPY3;V9GYB2;Q9BWG4-2;Q9BWG4 U3KPY3 SSBP4 Single-stranded DNA-binding protein 4 1 S(0.236)S(0.764)PGAVAGLSNAPGTPR 140.68 9.1475e-05 7470600.0 12487.0 16334.0 17835.0 14621.0 17548.0 15300.0 18886.0 9265.6 15097.0 15768.0 True False 14600.802470508019 17955.531572354677 18260.254039614156 13801.832771921565 14109.59536937201 14497.64106588934 17096.981357200777 9022.387817714698 15317.765064282023 18626.61358058068 0.7838677925723545 0.9639718725401785 0.9803313930692976 0.7409738067638216 0.7574965416194641 0.7783294050295845 0.9178792099399843 0.4843815425000848 0.8223590937781453 1.0 14.185077787882284 -5.770675808643333 24.99507337043897 0.7684310488091842 0.9148485097075357 0.13907966572388097 0.13578653002565225 304.27223314662535 823404.3231941838 0.03711466103825662 0.05591963963603502 1.6956030588387576e-06 5.770675808643333 0.1464174608983515 SS(ph)PGAVAGLSNAPGTPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPGAVAGLSNAPGTPR 17 0 U3KPY3;V9GYB2;Q9BWG4-2;Q9BWG4 U3KPY3 SSBP4 Single-stranded DNA-binding protein 4 1 S(0.18)S(0.82)PGAVAGLSNAPGTPR 139.08 7.5906e-05 11398000.0 15406.0 25456.0 21366.0 19439.0 21492.0 20942.0 20093.0 24820.0 24020.0 18627.0 True False 15186.307614885609 25397.058196011967 19609.36995514509 20868.608906603036 20227.882814897748 20046.35947818636 21133.317224195922 25973.227809864722 21314.61465818659 21846.652131082632 0.6951320286406298 1.1625148807069594 0.897591531987896 0.9552314368988339 0.9259030946036003 0.9175941173002485 0.9673480905629562 1.1888882403593064 0.9756467274846622 1.0 14.415124591817817 -7.543344962644765 24.798066880835762 1.0649841990794884 0.9370035021995257 0.18822150944550076 0.11802501312641601 346.20206327403145 419473.19825138286 0.05155708883920184 0.02977049329004242 2.86190383990527e-08 7.543344962644765 -0.12798069687996272 SS(ph)PGGQDEGGFMAQGK ddPTM_PC-9_AZD4547_30min_R2 4 SSPGGQDEGGFMAQGK 16 0 A0A1B0GTU4;F5GZ78;P49023;A0A1B0GV30 A0A1B0GTU4 PXN Paxillin 1 S(0.01)S(0.99)PGGQDEGGFMAQGK;S(0.245)S(0.755)PGGQDEGGFMAQGK;S(0.147)S(0.853)PGGQDEGGFMAQGK;S(0.022)S(0.978)PGGQDEGGFMAQGK 303.44 2.0702999999999994e-128 198370000.0 331289.0 311412.0 479160.0 427353.0 402023.0 470904.0 423434.0 504430.0 436159.0 413502.0 True False 436632.01076072606 412069.8390064295 472806.02532241785 328833.3683880324 346209.04587210936 441458.2984380936 461118.8056996496 426481.9341482498 459213.47430375376 399025.42084021267 1.0942461005149162 1.0326906945897072 1.184902015332377 0.8240912764295079 0.8676365659689304 1.1063412890049251 1.1556126041511072 1.0688089326495114 1.150837641714168 1.0 18.606121134047008 -6.897642280764558 22.709833059993173 1.1043842551448455 1.001312097111076 0.17052792892753377 0.10466750957394047 11.07230089817139 2428.688248272698 0.039142479840356036 0.03452046889891297 1.2657785133606959e-07 6.897642280764558 -0.10307215803376946 SS(ph)PGGQDEGGFMAQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSPGGQDEGGFMAQGK 16 0 A0A1B0GTU4;F5GZ78;P49023;A0A1B0GV30 A0A1B0GTU4 PXN Paxillin 1 S(0.03)S(0.97)PGGQDEGGFMAQGK;S(0.055)S(0.945)PGGQDEGGFMAQGK;S(0.056)S(0.944)PGGQDEGGFMAQGK 205.33 1.2423e-21 154933000.0 273220.0 304620.0 326268.0 320722.0 363115.0 281749.0 359983.0 289620.0 288336.0 238794.0 True False 319470.7496590219 334860.6604365545 334047.466498281 302752.9861347538 291965.22239283816 266973.5864492322 325882.8041887754 282017.78187775525 292552.36852187983 282085.4619077363 1.1325317777756072 1.1870893954332171 1.1842066026342764 1.0732668890032246 1.0350239974023663 0.946428024484839 1.1552626710530876 0.9997600726052192 1.037105445078084 1.0 18.10577278880382 -5.899538779319283 3.5430826435347056 1.0322799186268055 1.169981486598265 0.589270995729744 0.05170763538923441 0.16367299521051293 4.00067251422715 0.014912023466035273 0.02318813873852828 1.2602631005972175e-06 5.899538779319283 0.1377015679714595 SS(ph)PGGQDEGGFMAQGK ddPTM_PC-9_Lapatinib_30min_R1 3 SSPGGQDEGGFMAQGK 16 0 A0A1B0GTU4;F5GZ78;P49023;A0A1B0GV30 A0A1B0GTU4 PXN Paxillin 1 S(0.041)S(0.959)PGGQDEGGFMAQGK;S(0.093)S(0.907)PGGQDEGGFMAQGK;S(0.092)S(0.908)PGGQDEGGFMAQGK 146.27 6.4747e-06 165806700.0 354952.0 442317.0 473344.0 417162.0 488905.0 432981.0 421786.0 412057.0 449004.0 330633.0 True False 349890.31938977516 441292.8421623753 434427.4834806787 447841.4850916368 460148.56912421284 414463.41195800854 443624.01526525157 431202.6725080358 398432.4412982682 387782.47350922046 0.9022850265084393 1.1379906837173819 1.1202865347403308 1.1548780970911732 1.1866151787627701 1.0688038791628205 1.1440022321037244 1.1119705039938659 1.0274637677476017 1.0 18.564888074290153 -10.447442950092153 13.156253623205362 1.0000000047457984 1.102571612365644 0.11208170154135899 0.07750394732278595 0.0 0.0 0.07358923294553588 0.017848010608389853 3.56908630531149e-11 10.447442950092153 0.10257160761984552 SS(ph)PGHAPAR ddPTM_PC-9_AZD4547_30min_R2 1 SSPGHAPAR 9 0 M0QXP1;Q10586 M0QXP1 DBP D site-binding protein 1 S(0.406)S(0.594)PGHAPAR 90.82700000000001 0.00633 0.0 3063.4 2419.4 4432.4 5525.0 6119.8 4483.7 2281.2 3632.4 4833.2 6005.9 True False 4037.497477321638 3201.423736054343 4373.623479921287 4251.296610399085 5270.171405437344 4203.333530203353 2484.222380730034 3071.0960442481573 5088.673084826637 5795.635269053685 0.6966445074416981 0.5523853015990555 0.7546409111136863 0.7335341878912334 0.9093345527759308 0.7252584634936277 0.428636769811027 0.5298980873842338 0.8780181720540738 1.0 12.500751090722487 -8.478465836198037 5.4603925122812695 0.9993629274932103 0.670581036864188 0.43425930485258357 0.12815238377002106 0.17764769971446856 12.723001649534208 0.13676976682211492 0.035514193460928135 3.323029248128163e-09 8.478465836198037 -0.3287818906290223 SS(ph)PGPDTLVVLEFNPASK ddPTM_PC-9_AZD4547_30min_R2 1 SSPGPDTLVVLEFNPASK 18 0 O60303 O60303 KIAA0556 Uncharacterized protein KIAA0556 1 S(0.031)S(0.969)PGPDTLVVLEFNPASK 178.02 1.5228e-08 25601000.0 80358.0 83560.0 91795.0 75076.0 82934.0 98490.0 106050.0 125520.0 110530.0 90444.0 True False 105910.17244976574 110569.13589513951 90577.7383222125 57768.38811263742 71420.04564504405 92331.40473040777 115488.24455392783 106123.7681626551 116372.39014853284 87277.58308901121 1.213486541461074 1.2668675275113208 1.037812174860933 0.6618926197087923 0.8183091593199294 1.0579051511571116 1.3232291782890642 1.2159338561704138 1.333359449583393 1.0 16.41332353031985 -7.098437380909802 5.585066786121205 1.234022633083439 0.9924649344757313 0.23771857450474088 0.18415160609648956 0.35286505518231437 16.181918040732537 0.0794600491827768 0.06154240326346907 7.971914259745282e-08 7.098437380909802 -0.2415576986077077 SS(ph)PGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPR 36 1 P40222 P40222 TXLNA Alpha-taxilin 1 S(0.446)S(0.483)PGQPEAGPEGAQERPS(0.069)QAAPAVEAEGPGS(0.001)S(0.001)QAPR 54.52 0.00026247 55224000.0 3619.6 1431.1 5543.2 5333.8 7304.9 4623.9 6944.4 2910.4 3701.2 1166.4 True False 4232.326789641295 1573.1701501895905 5675.370910703065 5034.964478412917 5873.557283663414 4381.4145440892635 6286.576158897864 2834.005083823698 3755.3230480175293 1377.8590867826804 3.071668815948252 1.1417496645923089 4.118977742459233 3.654194051272418 4.262814202124434 3.1798712844576333 4.5625682765406035 2.0568177914630867 2.725476853214547 1.0 10.428212636278372 -5.266612410156354 24.999822143017994 3.335658064287835 2.106709242400016 0.1226272216486195 1.1148811132485976 680.0908873784534 3286705.4884131695 0.2799597211722235 0.6122253940382976 5.41237139204227e-06 5.266612410156354 -1.228948821887819 SS(ph)PGSVAASPSGGGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPGSVAASPSGGGGR 16 0 Q9BXB5-2;Q9BXB5 Q9BXB5-2 OSBPL10 Oxysterol-binding protein-related protein 10 1 S(0.417)S(0.577)PGS(0.006)VAASPSGGGGR 92.26899999999999 0.0030658 3048100.0 7089.3 7325.5 10166.0 8887.6 9264.1 7654.9 7554.3 6345.0 7922.3 6688.5 True False 8289.378469942543 8052.727227457095 10408.395994769691 8389.656585987968 7448.8661078982905 7253.463568318715 6838.702015604246 6178.450473083204 8038.148649980894 7901.072103863128 1.0491460349905626 1.0191942462491663 1.3173397050358064 1.0618377450176608 0.9427665018088194 0.9180353593751192 0.865541020978729 0.7819762168810395 1.0173491070978513 1.0 12.947832711873858 -6.239396271805247 3.2211386671604907 0.9035969589679494 1.125931511245707 0.485442066611279 0.09707760680084077 0.20693292819167702 4.437370555985289 0.031113180753944807 0.039338305056517496 5.762404331159289e-07 6.239396271805247 0.22233455227775745 SS(ph)PIMR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPIMR 6 0 A0A087WWN8;A0A087WZV0;O43314-2;O43314;K7ENU7;H0Y9S9 A0A087WWN8 PPIP5K2 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 1 S(0.075)S(0.925)PIMR 84.916 0.036891 24689000.0 69004.0 66630.0 57526.0 67825.0 82473.0 72263.0 55183.0 72650.0 71020.0 57577.0 True False 68019.9903062162 66475.72232873506 52796.434336781575 72813.07675756725 77622.10028815661 69172.47994328062 58040.10572750732 76025.58422186419 63020.97972624522 67529.10773347001 1.007269199745444 0.9844010169822983 0.7818322514368665 1.0782472803424634 1.149461364046487 1.024335760755152 0.8594827871350715 1.1258194691677084 0.9332417063021493 1.0 16.043221874764402 SS(ph)PLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPLLR 6 0 P56524-2;P56524;Q9UQL6-2;Q9UQL6;Q9UQL6-3;Q9UKV0-10;Q9UKV0-3;Q9UKV0-4;Q9UKV0-2;Q9UKV0;Q9UKV0-5;Q9UKV0-7 P56524-2;Q9UKV0-10 HDAC4;HDAC5;HDAC9 Histone deacetylase 4;Histone deacetylase 5;Histone deacetylase 9 1 S(0.222)S(0.778)PLLR;S(0.222)S(0.778)PLLR 87.75399999999999 0.041749 0.0 16802.4 17229.4 27901.0 26372.0 28734.0 24615.0 23526.0 23783.0 22759.0 18773.4 True False 19646.714457472903 18939.820966862222 28566.26565513174 24894.462339177575 23103.778968744908 23324.146067769027 21297.44696650986 23158.721450171466 23091.807319202144 22176.86880984736 0.8859102078806105 0.8540349464687382 1.2881108645259807 1.1225418048251925 1.0417962592846275 1.0517330587901674 0.9603450851931358 1.0442737272219478 1.0412564333224767 1.0 14.436768062840025 SS(ph)PLPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPLPAK 7 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 S(0.014)S(0.986)PLPAK;S(0.085)S(0.915)PLPAK 90.37 0.015974000000000002 43050200.0 353320.0 448730.0 377994.0 357514.0 435659.0 303090.0 396196.0 276815.0 293425.0 262151.0 True False 413130.0976119084 493276.9488467427 387006.81051022705 337483.6496560275 350294.7463542999 287195.4268405489 358665.44666935835 269548.8995597363 297715.78551943833 309676.90111382544 1.3340681727503385 1.5928761463078347 1.249711583648204 1.0897927757678683 1.1311620114202345 0.9274034511698592 1.1581924430893429 0.8704197781308216 0.9613754995888742 1.0 18.240404250438246 -5.6676455991260655 1.7000171297812434 1.0046627495825773 1.4722142801387534 0.7513735356164556 0.10296093518690433 0.17328214337691855 1.0039973439735845 0.031181167487592993 0.07444619234108149 2.1495839011129053e-06 5.6676455991260655 0.46755153055617615 SS(ph)PLPAK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPLPAK 7 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 S(0.18)S(0.82)PLPAK 84.49799999999999 0.019915000000000002 26862000.0 439950.0 607810.0 589730.0 471130.0 666900.0 540150.0 629330.0 583230.0 535120.0 525610.0 True False 433676.2323230507 606402.6532887347 541244.6758236302 505778.4718436071 627674.2531758464 517049.0436511491 661913.6280646599 610328.9949857936 474849.15053658606 616460.9881686993 0.7034933931688988 0.9836837446764563 0.8779869062460679 0.8204549542479675 1.018189739857599 0.8387376550576703 1.0737315755064814 0.9900529095910484 0.7702825639416454 1.0 19.23365007310972 -6.2485663647682435 24.482810943650737 0.9487752764159316 0.8584662608132916 0.18141353937112437 0.10500005585203034 1178.365737895388 2241097.0537330615 0.030313172292650924 0.03886673635290637 5.64200718948762e-07 6.2485663647682435 -0.09030901560264004 SS(ph)PLSFPSVPQEETLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPLSFPSVPQEETLR 16 0 Q9ULD5 Q9ULD5 ZNF777 Zinc finger protein 777 1 S(0.207)S(0.793)PLSFPSVPQEETLR;S(0.161)S(0.839)PLSFPSVPQEETLR 172.85 2.6247e-10 1584600.0 7941.2 9433.8 4839.5 8245.9 12308.1 5041.6 13260.8 5859.700000000001 5907.0 8444.9 True False 9285.488314150576 10370.3253181878 4954.892033905953 7783.908956568502 9896.416159435135 4777.209620770439 12004.641024121993 5705.8890838653515 5993.378700053919 9975.893520208385 0.9307926448233194 1.0395384931866412 0.4966865397940265 0.7802718564307516 0.9920330584310818 0.47887536200072117 1.2033649917978706 0.5719677212178346 0.6007861539332794 1.0 13.284230351003773 -5.19177744490713 24.999790042840996 0.7642276274439667 0.9851661611210708 0.12857520191490812 0.22873069754904926 332.91397380544163 119471.475830873 0.055671415478368985 0.14729284750312785 6.430171483499287e-06 5.19177744490713 0.22093853367710414 SS(ph)PNPFITGLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPNPFITGLTR 12 0 A0A0D9SGJ6;J3KQV8;O43426 A0A0D9SGJ6 SYNJ1 Synaptojanin-1 1 S(0.219)S(0.781)PNPFITGLTR 91.20200000000001 0.0065327 4576700.0 11286.0 9984.2 13028.0 13691.0 15420.0 9931.1 11292.0 12715.0 9268.0 8553.8 True False 13196.496891339279 10975.365392720914 13338.636928965145 12923.937656820885 12398.561693396196 9410.29563329762 10222.340012999632 12381.244722656103 9403.52696666661 10104.53622815646 1.305997286106711 1.0861820023107913 1.3200642392470037 1.2790233381328393 1.2270292681862425 0.931294165394318 1.0116585048717932 1.2253154863412294 0.9306243012384403 1.0 13.302715486849177 -6.6912090679782725 8.439278399927824 1.0336003145826298 1.2420451535977004 0.5658891393237733 0.097690136275937 0.2243231602381284 24.199230467796827 0.03222716634561506 0.0321648468122387 2.0360616881444193e-07 6.6912090679782725 0.2084448390150706 SS(ph)PNVANQPPS(ph)PGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPNVANQPPSPGGK 15 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 2 S(0.37)S(0.63)PNVANQPPS(1)PGGK 130.36 0.00048566 0.0 5686.5 8565.2 13949.0 13957.0 17862.0 17031.0 20612.0 16265.0 15543.0 15636.0 True False 6649.112136505472 9415.496450565217 14281.597061877093 13175.03453920452 14362.069323439873 16137.864378637993 18659.482142042914 15838.06098419201 15770.286970532925 18470.6830254921 0.35998193068056966 0.5097535612283817 0.7732035161973443 0.7132943877073278 0.7775602723309273 0.8737015494427307 1.0102215557643561 0.8574702387742399 0.8538009638716524 1.0 14.172949596128088 -4.780791308595011 0.5680478657520968 0.9228808890427953 6.890894459961834e-19 0.8846426780136778 0.06577823508634792 1.3198374415599912 0.32374614239026445 0.037857014905869804 0.8093386401141509 1.656565801339979e-05 4.780791308595011 -0.9228808890427953 down SS(ph)PPAPPLPPGS(ph)GSPGTPQALPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPPAPPLPPGSGSPGTPQALPR 23 0 Q9Y3L3;A0A2R8Y5V0 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 2 S(0.345)S(0.655)PPAPPLPPGS(0.653)GS(0.345)PGT(0.002)PQALPR 140.84 6.619300000000001e-05 3484000.0 5421.7 3632.3 5878.3 5797.3 7138.3 6164.3 7305.8 6579.0 7050.8 5355.3 True False 6339.486726543871 3992.890738965586 6018.460965576895 5472.496076100192 5739.601357715309 5841.033256370045 6613.741734588443 6406.308221026698 7153.904611196907 6326.173497468522 1.0021044679031765 0.631169970372039 0.9513588218826498 0.8650562742691238 0.9072785246898563 0.9233122137272064 1.0454569001680074 1.0126671713303852 1.1308423036547464 1.0 12.627117407464134 -6.998598059110208 1.0121970175798842 1.0644563756037702 0.8447678718151581 0.4239333563590928 0.09668439231558582 0.47432539776394983 1.0036877785096263 0.058807054861838515 0.042328800826323607 1.0032333040817272e-07 6.998598059110208 -0.21968850378861204 SS(ph)PPFWALPPSAPSER ddPTM_PC-9_Lapatinib_30min_R1 1 SSPPFWALPPSAPSER 16 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 S(0.422)S(0.578)PPFWALPPSAPSER 95.822 0.0024099 3540200.0 3266.3 3504.3 5526.7 3780.0 4701.4 4513.4 4173.6 5196.0 4903.9 5160.2 True False 3219.72196303394 3496.186008653552 5072.316059678942 4057.9938097103504 4424.872895308033 4320.372403249277 4389.688586418362 5437.425128930584 4351.571141643681 6052.133694465704 0.531997825160104 0.5776782512009929 0.8381037689760978 0.6705063064652935 0.7311260984459581 0.7138593794119231 0.7253125604995238 0.8984310994158585 0.7190143776273348 1.0 12.563228142377385 -6.007002927437404 0.07002174938298067 1.3806826672925416 2.353069968460765e-12 0.6322627011020014 0.08094698834798897 50.767575834301375 0.9167446279928895 6.403726156474009 11.821409566123146 9.840044728856807e-07 6.007002927437404 -1.3806826672901886 SS(ph)PPGHYYQK ddPTM_PC-9_AZD4547_30min_R2 2 SSPPGHYYQK 10 0 D6RI08;D6RDK1;D6RIV2;D6R9T5;D6RG39;D6RIT9;D6RDK6;D6RBN5;Q9NX40-3;Q9NX40-2;Q9NX40-4;Q9NX40 D6RI08 OCIAD1 OCIA domain-containing protein 1 1 S(0.433)S(0.567)PPGHYYQK;S(0.421)S(0.579)PPGHYYQK 81.625 0.0090838 17151100.0 82576.0 107970.0 166759.0 168158.0 154346.0 153825.0 176708.0 224778.0 166158.0 149976.0 True False 108833.45031249974 142869.19103157287 164547.66670160487 129391.77111520176 132917.72210589118 144206.2984328857 192434.6696712448 190043.7249845868 174940.77266171988 144725.3858891419 0.7519997244703497 0.9871743658089752 1.136964781200491 0.8940502754251729 0.9184133197454711 0.9964132936798398 1.3296538716341562 1.313133309799279 1.2087773792202747 1.0 17.142958477744727 -7.156963839350758 5.360168245045241 1.2378933316696403 0.9503992537349584 0.5249956313747413 0.12325857481880884 0.17546517123994163 7.386398552612802 0.04781363063117057 0.0367823992862968 6.966845197194625e-08 7.156963839350758 -0.28749407793468196 SS(ph)PPLRTPDVLESSGPAVR ddPTM_PC-9_AZD4547_30min_R2 2 SSPPLRTPDVLESSGPAVR 19 1 E9PJN1;O75676-2;O75676;A0A0A6YYC0 E9PJN1 RPS6KA4 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-4 1 S(0.148)S(0.851)PPLRT(0.001)PDVLESSGPAVR;S(0.235)S(0.763)PPLRT(0.002)PDVLESSGPAVR 88.555 0.00052339 99671000.0 23214.5 19201.6 31994.0 48616.0 42148.0 26917.0 20940.4 23937.2 33888.0 32225.0 True False 30596.228108403484 25408.141692246423 31569.738655491747 37408.33230971253 36296.4777274377 25233.875734880494 22804.055033069966 20238.2557621344 35679.25049627683 31096.81255852661 0.9839023871279095 0.8170657891199085 1.015208185600214 1.2029635590241654 1.1672089433322117 0.8114618077781569 0.7333245164645401 0.6508144757294476 1.1473603742867766 1.0 14.92447909039814 -6.782991965419832 24.99688260252409 0.8383138430129696 1.0330158047923286 0.20061439849676754 0.1627285214168687 363.194430843978 421233.29189671134 0.06010730083853133 0.05305554109372031 1.6481928833137078e-07 6.782991965419832 0.19470196177935895 SS(ph)PPSAGNSPSSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPPSAGNSPSSLK 14 0 P57682;P57682-2 P57682 KLF3 Krueppel-like factor 3 1 S(0.174)S(0.826)PPSAGNSPSSLK 128.22 2.6351e-05 14226000.0 20734.0 30008.0 25232.0 28055.0 30124.0 23416.0 23058.0 18381.0 19774.0 17180.0 True False 24243.856684833278 32986.995924036906 25833.626572892877 26483.169305537194 24221.41844694337 22188.023738487907 20873.779314536445 17898.51822627935 20063.15734126733 20294.598003194835 1.1945965463822805 1.625407703017522 1.2729311794609617 1.3049368753876345 1.193490920250323 1.0932970308155403 1.0285386934617002 0.8819350954111884 0.9885959474589706 1.0 14.308808142864624 -6.598260740204699 0.9483055749912844 0.9491514092248277 1.4006141750357974 0.7119677326870759 0.10823081161883452 0.2731168509941832 0.5344424548779022 0.05702106419475229 0.06221008737695451 2.5219661886109476e-07 6.598260740204699 0.4514627658109698 SS(ph)PPSAGNSPSSLK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPPSAGNSPSSLK 14 0 P57682;P57682-2 P57682 KLF3 Krueppel-like factor 3 1 S(0.012)S(0.988)PPSAGNSPSSLK 173.33 0.00014571 15778000.0 8925.0 13461.0 10346.0 11419.0 13798.0 15536.0 14128.0 15394.0 14839.0 13967.0 True False 8797.72786335545 13429.831881541375 9495.391816714917 12258.791352667326 12986.428767911742 14871.561496184855 14859.478711165084 16109.261438559937 13167.675558402614 16381.17734014234 0.537063220834346 0.8198331293704607 0.5796525865968318 0.748346171836316 0.792765287760379 0.9078444843974586 0.9071068826507172 0.983400710709842 0.8038296201174144 1.0 13.99975142894259 -6.430337302621911 1.4518653804171162 0.9245881711859955 0.6611755809465143 0.6552908732042193 0.08647171229641651 0.247931538746664 1.0605903102150593 0.03237599381856053 0.03877829459037536 3.712467816063978e-07 6.430337302621911 -0.26341259023948116 SS(ph)PPSPYMGFSGNSK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPPSPYMGFSGNSK 15 0 V9GZ20;V9GXZ5;Q70EL4-2;Q70EL4-3;Q70EL4-4;Q70EL4 V9GZ20 USP43 Ubiquitin carboxyl-terminal hydrolase 43 1 S(0.011)S(0.989)PPSPYMGFSGNSK 144.88 9.544e-05 4178300.0 24494.0 21435.0 23991.0 19421.0 17216.0 14660.0 15337.0 14414.0 17054.0 11635.0 True False 24144.711068350513 21385.36857446249 22018.552587938117 20849.28512655679 16203.388727958278 14033.025974129128 16131.074815482665 15083.72706089405 15133.198933418576 13646.094247337012 1.7693495758364903 1.5671420837970373 1.6135424678189483 1.5278573303584986 1.1874012031772616 1.0283547599612706 1.1821019643500255 1.1053512299929766 1.108976580340691 1.0 13.736200465030704 -6.229188346724571 2.3248998490984345 1.0949134069776263 1.6418699551304048 0.9368318054608146 0.06677218782321442 0.06945794597438933 0.7380574615276426 0.021697624443530853 0.02835772537807345 5.899451746890492e-07 6.229188346724571 0.5469565481527785 SS(ph)PQHSLSNPLPR ddPTM_PC-9_AZD4547_30min_R2 1 SSPQHSLSNPLPR 13 0 Q86UE8-2;Q86UE8 Q86UE8-2 TLK2 Serine/threonine-protein kinase tousled-like 2 1 S(0.036)S(0.912)PQHS(0.026)LS(0.026)NPLPR 100.73 0.0021815000000000003 5279300.0 14573.0 13866.0 21385.0 28733.0 23966.0 18598.0 18704.0 19977.0 15325.0 21423.0 True False 19206.91086276955 18347.913335591267 21101.42092728922 22109.050770424776 20638.73458327255 17435.06411997279 20368.619765550815 16890.013675791626 16135.048213392427 20672.987290653717 0.9290825071736496 0.8875308187262506 1.0207243215802293 1.0694656974137602 0.998343117668502 0.8433742001019467 0.9852770419280185 0.8170088550012132 0.7804894370871646 1.0 14.335459255879952 -6.754147548321789 24.994819057875272 0.8800459039059338 0.9829533590078275 0.26927240668384966 0.0786434781574529 233.43971378595228 800180.403511067 0.02751224383565596 0.0269769873793345 1.7613775298244904e-07 6.754147548321789 0.1029074551018937 SS(ph)PQHSLSNPLPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPQHSLSNPLPR 13 0 Q86UE8-2;Q86UE8 Q86UE8-2 TLK2 Serine/threonine-protein kinase tousled-like 2 1 S(0.193)S(0.61)PQHS(0.193)LS(0.003)NPLPR 81.23899999999999 0.0067199 3831400.0 15236.0 14982.0 20308.0 13745.0 17109.0 15042.0 10905.0 12698.0 21590.0 9781.2 True False 15018.731846059787 14947.310099491337 18638.354631146973 14755.853151975862 16102.68225758819 14398.688724614616 11469.607541425197 13287.995436328054 19158.306847221007 11471.867387370243 1.3091793462147587 1.3029535292525543 1.6247010187431692 1.2862642718674613 1.403667050345802 1.25513033217823 0.9998030097569351 1.1583114577280806 1.6700251319426007 1.0 13.485812631514918 -6.848244333454222 4.847106171568861 1.2087538892915985 1.3885012673361325 0.15891338730360427 0.19574932814005527 0.41285118921664715 16.850567885799364 0.07044330699782671 0.06247034255235964 1.4182593864933898e-07 6.848244333454222 0.179747378044534 SS(ph)PQKEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPQKEVK 8 1 A6NJA2;P54578-2;P54578-3;P54578 A6NJA2 USP14 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 14 1 S(0.008)S(0.992)PQKEVK 61.765 0.030476 10281000.0 45210.0 38108.0 44368.0 58677.0 119050.0 119830.0 63693.0 93660.0 132950.0 133010.0 True False 52863.16006179771 41891.110393001836 45425.901386576996 55389.51792340068 95723.00710757548 113545.90385134128 57659.537942612966 91201.52424097307 134894.14223331073 157123.6600934195 0.3364430285697735 0.26661236358734924 0.2891092363783313 0.352521815558957 0.6092208331365396 0.7226531241942263 0.3669691624312398 0.5804442449135175 0.8585221484346026 1.0 17.26154091623568 -7.48391392925869 0.18284331171426838 1.1857428450108263 4.356999352550664e-10 0.7517981198375175 0.12173035857319274 2.133124943451954 0.3231599033585234 0.7133052533059541 0.9968329892338474 3.281603231901209e-08 7.48391392925869 -1.1857428445751264 down SS(ph)PQLDPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPQLDPLR 9 0 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 1 S(0.191)S(0.809)PQLDPLR;S(0.162)S(0.838)PQLDPLR 136.96 0.00097226 79509000.0 82637.0 110200.0 102710.0 79112.0 96401.0 73809.0 77447.0 59687.0 63295.0 57938.0 True False 96625.81194485255 121139.92771357203 105158.99592984434 74679.61112456475 77511.91607036893 69938.32610668139 70110.65949227603 58120.279493603986 64220.56963262447 68441.70076304438 1.41179735260212 1.7699724928370344 1.5364754931196236 1.091141954276048 1.1325246919086218 1.021867155943692 1.0243851147856455 0.8491939686716037 0.9383251572745962 1.0 16.062587990515333 -5.789473881523691 2.931809593354346 0.9955223095863137 1.6112084239236173 0.8599228861058876 0.10509052647550317 0.08759484222998952 1.5386955750681628 0.0318079932796483 0.054754607665444786 1.6237760014578341e-06 5.789473881523691 0.6156861143373036 SS(ph)PQLDPLR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPQLDPLR 9 0 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 1 S(0.489)S(0.511)PQLDPLR 84.507 0.013153999999999999 3672300.0 10705.0 19862.0 27613.0 15853.0 19690.0 22213.0 17421.0 18690.0 20769.0 15305.0 True False 10552.344736943427 19816.010759317636 25342.765729262443 17018.882504057714 18531.872912029434 21263.00177103209 18322.974138392336 19558.405631199505 18429.776512734283 17950.4488573694 0.5878596585962949 1.1039284263458597 1.4118179400766455 0.9481034507430025 1.0323905022810242 1.184538723236592 1.0207529786014236 1.0895775245848502 1.02670282281928 1.0 14.131732299152347 -4.76104562517056 24.99817043559822 1.0981443504694155 0.5878591078993471 0.5968001425207501 0.12390457245890198 6.5450503767062145 415008.99348247703 0.030933630699873198 0.17639822760710727 1.7336218610903527e-05 4.76104562517056 -0.5102852425700684 SS(ph)PQLDPLRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPQLDPLRK 10 1 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 1 S(0.309)S(0.691)PQLDPLRK 84.734 0.0056637 169850000.0 77751.0 88141.0 82506.0 64022.0 84070.0 64265.0 80214.0 40824.0 46810.0 51066.0 True False 90912.70864775123 96891.05597642431 84473.25594574763 60435.05490212452 67597.08700154453 60894.83026793325 72615.54922093113 39752.41325660346 47494.50769418044 60323.86156176642 1.5070770718924298 1.6061812600842247 1.4003290531932264 1.0018432729185323 1.1205696262055598 1.0094650556410785 1.2037616183867654 0.6589832319653547 0.7873253877414689 1.0 15.880441163555469 -5.58716061727889 0.5798623978110418 0.8670769757894559 1.7797595814892615 0.7267100331011533 0.15103270350558715 0.9312203222985789 0.44501444960613695 0.09820427675403115 0.5115366240150283 2.5872558805370556e-06 5.58716061727889 0.9126826056998056 SS(ph)PRPTAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPRPTAEK 9 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 S(0.041)S(0.959)PRPTAEK 59.367 0.035151999999999996 22478000.0 12226.0 17640.0 20684.0 15857.0 26576.0 23605.0 15399.0 19546.0 19529.0 20099.0 True False 14295.620325492995 19391.18262130136 21177.185004506828 14968.58369908763 21368.623577412283 22367.1122457724 13940.29524089456 19032.938210698863 19814.57467976178 23742.78959640354 0.6021036520349924 0.8167187997251449 0.8919417374491942 0.6304475570703372 0.9000047568399087 0.9420591525252145 0.5871380523460553 0.801630243717524 0.8345512476243823 1.0 14.535201830134241 -14.522878722753878 0.27484081656904935 2.5411347937038484 0.7675090361887339 0.2395253336666714 0.12125219055315409 343.49284614597656 3.310856282443104 301.1598118013601 0.14427757301376545 3.000000155607271e-15 14.522878722753878 -1.7736257575151146 SS(ph)PRPTAEK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPRPTAEK 9 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 S(0.195)S(0.805)PRPTAEK 54.343 0.045057 35528000.0 36938.0 42355.0 41212.0 36125.0 41528.0 38332.0 48354.0 44951.0 48183.0 33215.0 True False 36411.25734640043 42256.929599783456 37823.708442920484 38781.75300946728 39085.40468718936 36692.62971625633 50857.5335220609 47039.5875616934 42756.12315051641 38956.16849379449 0.934672447373785 1.0847301270532999 0.9709298913455927 0.995522776210525 1.0033174770104882 0.9418952411118477 1.305506560024306 1.207500362084802 1.0975443634126194 1.0 15.249564168704069 -7.2433944169039055 24.999132939614206 1.1699295298763825 0.9930774567917743 0.47878643421722356 0.08303053918530492 642.7301282427519 890426.7801221099 0.030669083983536023 0.02370569310382435 5.7095986767342036e-08 7.2433944169039055 -0.17685207308460826 SS(ph)PSGASSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPSGASSPR 10 0 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 S(0.015)S(0.402)PS(0.075)GAS(0.254)S(0.254)PR 84.81700000000001 0.012301000000000001 5270400.0 4790.6 8210.1 7673.0 5385.0 12773.0 10469.0 5616.4 7312.3 9637.5 11624.0 True False 5601.553961337047 9025.144469339355 7855.953420014541 5083.295908405553 10270.22234174771 9919.987210378791 5084.37393278526 7120.359873022276 9778.430205141287 13731.339184466631 0.40793937765907934 0.6572661521280395 0.5721185176826357 0.3701966603633209 0.7479403285999768 0.7224340668534811 0.3702751686839752 0.5185481020727443 0.7121250210032672 1.0 13.74518471447164 -8.596845508376116 3.160211602449475 0.9994794194270671 0.5523872560235327 0.5374833399095981 0.1293930683078077 0.26315428044230255 6.555352958916427 0.1266052300818817 0.03359407799559932 2.530197903953623e-09 8.596845508376116 -0.4470921634035344 SS(ph)PSGASSPR ddPTM_PC-9_Lapatinib_30min_R1 2 SSPSGASSPR 10 0 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 S(0.05)S(0.95)PSGASSPR;S(0.018)S(0.981)PSGASSPR 136.52 0.00011549 3682800.0 12572.0 19016.2 17850.8 17076.1 22258.5 16621.0 22795.1 28406.0 24653.8 19288.4 True False 12392.720974577569 18972.169157251843 16383.176130080685 18331.933358199716 20949.298791894722 15910.158575443398 23975.318740719078 29725.846461201352 21877.02942797671 22622.374239822555 0.5478081497194246 0.8386462427031557 0.7242023297997209 0.8103452433356751 0.9260433308108443 0.7032930499150029 1.059805592753165 1.3140020647733088 0.9670527591867966 1.0 14.465462729048143 -7.340327287482316 5.215472042465662 1.1183424554119594 0.7707451492386421 0.607801784326524 0.1277880909475672 0.14521933793127062 6.972589401048156 0.05289065944238426 0.035275769795561296 4.567438543915982e-08 7.340327287482316 -0.3475973061733173 SS(ph)PSHTTNGCQGEK ddPTM_PC-9_AZD4547_30min_R2 1 SSPSHTTNGCQGEK 14 0 Q8N8R5 Q8N8R5 C2orf69 UPF0565 protein C2orf69 1 S(0.215)S(0.633)PS(0.125)HT(0.026)T(0.001)NGCQGEK 92.096 0.0024259 2127500.0 2266.1 2271.6 4931.8 9944.3 7406.1 5911.1 3440.5 6305.8 4429.2 5829.9 True False 2986.6726621918674 3005.8502764408718 4866.401109619127 7651.795272903452 6377.890853591535 5541.4779825557125 3746.6978348683483 5331.383502868642 4663.318469608984 5625.796975483456 0.53088881010236 0.5342976807623888 0.8650154157404393 1.360126450749832 1.1336866370019418 0.9850120803692001 0.665985255279564 0.9476672418329647 0.8289169498883737 1.0 12.457841774081801 -5.33568871568851 4.128220866030124 0.986550250605234 0.5287241911351201 0.5210767425780927 0.1715712923260177 0.1830783417901049 5.925937089288832 0.05088038755310656 0.11696170559837657 4.616483464339776e-06 5.33568871568851 -0.4578260594701139 SS(ph)PSIICMPK ddPTM_PC-9_AZD4547_30min_R2 1 SSPSIICMPK 10 0 F8VQD8;A0A087X050;F8VVY1;F8VX63;F8VUB4;F8VV52;F8VP97;Q9NZN8-4;Q9NZN8-5;Q9NZN8 F8VQD8 CNOT2 CCR4-NOT transcription complex subunit 2 1 S(0.032)S(0.965)PS(0.003)IICMPK 97.81299999999999 0.0044031999999999995 5498000.0 28765.0 31023.0 40267.0 42390.0 33934.0 34528.0 24978.0 42793.0 37004.0 33140.0 True False 37911.67165083139 41050.57806216987 39733.033270009604 32617.64041897142 29222.849843477026 32368.958701710937 27200.993611202324 36180.32513531316 38959.955894836756 31979.778687030936 1.1854888685082137 1.283641718221693 1.2424424089627275 1.0199457831832701 0.9137914971040136 1.0121695656023357 0.8505685382442437 1.1313500787291475 1.218268465085925 1.0 14.964872334370579 -5.764378116730526 8.25979120507432 1.0141994162399648 1.242274048313508 0.501313916187694 0.09868287995371795 0.09585098477495087 56.895138896643566 0.029260422338702578 0.046578245844146396 1.7203700895095302e-06 5.764378116730526 0.22807463207354317 SS(ph)PSIICMPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSPSIICMPK 10 0 F8VQD8;A0A087X050;F8VVY1;F8VX63;F8VUB4;F8VV52;F8VP97;Q9NZN8-4;Q9NZN8-5;Q9NZN8 F8VQD8 CNOT2 CCR4-NOT transcription complex subunit 2 1 S(0.008)S(0.982)PS(0.01)IICMPK;S(0.033)S(0.965)PS(0.003)IICMPK;S(0.048)S(0.938)PS(0.014)IICMPK 95.48299999999999 0.006657 18776000.0 134782.0 158517.0 127585.0 129524.0 143730.0 94961.0 118089.0 78754.0 87893.0 89259.0 True False 157597.93053415636 174253.5201576432 130627.11026880711 122267.19020247372 115567.13827443802 89981.07799071362 106902.75502967696 76686.79094676036 89178.26884778033 105440.9501261446 1.494655827224751 1.6526171278727522 1.238865071990825 1.159579746352807 1.0960365791106674 0.8533788616573018 1.0138637303797389 0.727296091841129 0.8457650347525477 1.0 16.68607575004812 -5.732325925262831 0.7966184790955584 0.8629178626135523 1.6670028699122281 0.854297137685309 0.10558276352569983 0.3064483027718059 0.33840037807883533 0.04770753106760899 0.17412715100027532 1.8521411241592821e-06 5.732325925262831 0.8040850072986758 SS(ph)PSILAVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPSILAVQR 10 0 O14646;O14646-2 O14646 CHD1 Chromodomain-helicase-DNA-binding protein 1 1 S(0.204)S(0.795)PS(0.001)ILAVQR 115.7 0.0011022 5668100.0 15886.0 17259.0 20760.0 17546.0 21887.0 18380.0 21180.0 16777.0 14397.0 12962.0 True False 18575.186037197913 18972.35945924263 21254.99713273843 16562.95450489951 17598.399467144132 17416.12044385922 19173.677070079015 16336.621526700852 14607.52888855192 15311.907992864462 1.2131202751384202 1.23905913411209 1.388135113053417 1.0817041555251017 1.1493276654578386 1.1374232689992225 1.252206914971941 1.0669226548588144 0.9539979534463771 1.0 13.902366445557279 -7.648812939296726 0.5286215050224683 0.9670716772872873 1.2504170339447715 0.5215181963338529 0.08519136898139151 0.7375393791006629 0.4544917928960553 0.08892036982323762 0.06036601102326686 2.2448486239310173e-08 7.648812939296726 0.2833453566574843 SS(ph)PSILAVQR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPSILAVQR 10 0 O14646;O14646-2 O14646 CHD1 Chromodomain-helicase-DNA-binding protein 1 1 S(0.224)S(0.775)PS(0.001)ILAVQR 131.42 0.00018045 5147800.0 25396.0 24448.0 30646.0 19498.0 18702.0 22831.0 24266.0 21041.0 21093.0 19826.0 True False 25033.84838294398 24391.392158080627 28126.404176980996 20931.947963421266 17601.98512954669 21854.57135166045 25522.37474555013 22018.641673946982 18717.284220863017 23252.89768351557 1.0765904844922172 1.0489614021469744 1.209587061354523 0.9001866454803321 0.7569802856022146 0.9398644267528677 1.0975997526382888 0.9469203354193755 0.8049441611800521 1.0 14.505122889884104 -5.778488825065845 24.993433923194118 0.920035449585062 1.1054378306269075 0.4477228227657386 0.09702330568572327 231.8996643389474 339949.9154498582 0.02927353361628535 0.04353967913267906 1.6653716793067499e-06 5.778488825065845 0.18540238104184548 SS(ph)PSKCPSLDDR ddPTM_PC-9_AZD4547_30min_R2 2 SSPSKCPSLDDR 12 1 P38398-8;P38398-4;P38398;P38398-7;H0Y8B8;B7ZA85;E7EUM2;A0A2R8Y7V5;P38398-6;P38398-5;P38398-3 P38398-8 BRCA1 Breast cancer type 1 susceptibility protein 1 S(0.227)S(0.771)PS(0.002)KCPSLDDR;S(0.228)S(0.766)PS(0.004)KCPS(0.002)LDDR 165.78 0.00033518 21864000.0 74747.0 60483.0 88667.0 111952.0 101139.0 86106.0 68911.0 94753.0 73010.0 79453.0 True False 98514.99116581581 80032.94694047078 87491.21764601133 86143.19604115808 87097.59563621806 80721.77820810702 75043.94550170425 80111.10105733022 76869.15954713082 76671.37465361114 1.2848992418733927 1.0438439026565869 1.1411197209034334 1.1235379100784235 1.135985836039994 1.052828106614691 0.9787739666954016 1.04486324158474 1.0025796445467847 1.0 16.22640042594022 -6.871662822096121 3.1298604685230313 1.0102932336609447 1.1397082157176988 0.5692568405792875 0.05746481224324265 0.19633946707456337 3.8357856245463333 0.020686240876007317 0.018112948198286648 1.3438078628850285e-07 6.871662822096121 0.12941498205675406 SS(ph)PSKCPSLDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPSKCPSLDDR 12 1 P38398-8;P38398-4;P38398;P38398-7;H0Y8B8;B7ZA85;E7EUM2;A0A2R8Y7V5;P38398-6;P38398-5;P38398-3 P38398-8 BRCA1 Breast cancer type 1 susceptibility protein 1 S(0.225)S(0.774)PS(0.001)KCPSLDDR 153.49 0.0010540999999999999 7808100.0 23418.0 16075.0 21566.0 25864.0 29683.0 21673.0 24882.0 22154.0 26457.0 19452.0 True False 27382.204873416908 17670.81976402604 22080.21522951045 24414.923932219364 23866.8292311984 20536.429726864033 22524.996829920026 21572.48097410329 26843.883573273484 22978.493618052737 1.1916449062572343 0.7690155872595236 0.9609078643938362 1.0625119443442592 1.038659436423968 0.8937239345720152 0.9802642942713866 0.9388118008377698 1.168217726517284 1.0 14.487996603077496 -8.244675068334805 24.833006855402125 1.0841088856985164 0.9737234107453538 0.12268660754662142 0.11111684432649611 1263.9979117470305 1872369.91151084 0.07222553909239787 0.027122412855501026 5.692786960825293e-09 8.244675068334805 -0.11038547495316253 SS(ph)PSPALEQPFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPSPALEQPFR 12 0 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 S(0.23)S(0.768)PS(0.002)PALEQPFR 98.182 0.011087 0.0 6551.9 10407.0 6818.8 7643.4 9060.3 10551.0 10655.0 8761.9 7418.3 8276.3 True False 7661.007264076356 11440.138182533057 6981.386052443003 7215.1650782371435 7284.999254907753 9997.686986026036 9645.681264480256 8531.909409000435 7526.778603455212 9776.727674845242 0.7835962623555046 1.1701398016810514 0.7140820819225194 0.7379938685211822 0.7451367673512568 1.0226005385983394 0.9865960866740557 0.8726753667234051 0.7698668566601303 1.0 13.255135952574584 -6.759736940833852 24.99999755843583 0.9259054890758966 0.8375034642460325 0.11355092831938562 0.13889720597492952 131.43420767383884 1930096.6365221438 0.049736363261532926 0.04728528669698879 1.7388537615722203e-07 6.759736940833852 -0.08840202482986415 SS(ph)PSPEVVKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPSPEVVKPK 11 1 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 S(0.079)S(0.744)PS(0.177)PEVVKPK 80.37100000000001 0.0076637 15693000.0 107910.0 85108.0 91884.0 109120.0 106630.0 116480.0 104820.0 102930.0 100590.0 84756.0 True False 126177.03168034942 93556.95978082293 94074.8630320107 103006.3601718131 85736.61694985985 110371.58374867907 94890.69076891783 100228.19656335004 102060.93845241636 100121.59187187317 1.2602379698658779 0.9344334027424266 0.939606145619413 1.0288126491599494 0.8563249479650508 1.1023754385559803 0.9477545152333436 1.0010647522625618 1.019369913564948 1.0 16.611393608723915 -4.755715454215555 24.99980455576389 0.9801613609103754 1.2602384188263982 0.6379862494997064 0.063081308703048 112.82369286288618 492718.5640153974 0.014806165932563061 0.12792134680046743 1.755030004884708e-05 4.755715454215555 0.2800770579160228 SS(ph)PSTGSLDSGNESK ddPTM_PC-9_AZD4547_30min_R2 1 SSPSTGSLDSGNESK 15 0 A0A0U1RQT1;A0A087X1H5;Q15057 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 S(0.147)S(0.85)PS(0.003)TGSLDSGNESK 127.07 2.1816999999999998e-05 7771100.0 25965.0 29606.0 33142.0 31644.0 35533.0 33018.0 28812.0 37466.0 29309.0 29758.0 True False 34221.32989444944 39175.56052311516 32702.515425401878 24348.96469492644 30599.85629422612 30953.379240416252 31376.212183760177 31676.49058303091 30858.213904490607 28716.18147763027 1.1917089297233912 1.3642329344391655 1.1388183854067413 0.8479179139431937 1.0655962847310747 1.0779072163382428 1.092631769589632 1.103088535908115 1.0745932194546468 1.0 14.809576299687219 -5.517289816009189 24.998320340180225 1.0427371097148719 1.2713596496018398 0.5905624533276643 0.07978516499907894 161.09485765878622 720548.3298380915 0.021883128163544437 0.03948807686855433 3.0388564409062916e-06 5.517289816009189 0.2286225398869679 SS(ph)PSTGSLDSGNESK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPSTGSLDSGNESK 15 0 A0A0U1RQT1;A0A087X1H5;Q15057 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 S(0.167)S(0.707)PS(0.113)T(0.013)GSLDSGNESK 144.8 0.00010797 6546400.0 21136.0 31118.0 30413.0 26731.0 33218.0 33364.0 31616.0 30269.0 31484.0 22902.0 True False 20834.59676413232 31045.948182884218 27912.560537574987 28696.88691200193 31264.18254910076 31937.099495282677 33252.92178172392 31675.408242417223 27937.94037878214 26860.580185003215 0.7756569895599158 1.1558182276426694 1.0391644687242874 1.0683643731576566 1.163942935475242 1.1889951473614775 1.2379822607215936 1.1792525710260802 1.0401093418816185 1.0 14.713202846674708 -4.7586991658027396 24.99992331583026 1.1280809445193694 0.7756565191325258 0.6531070720663106 0.07488576097241453 47.52231531128214 433479.4798725981 0.01941284272724953 0.13058836837555865 1.7430138346149946e-05 4.7586991658027396 -0.3524244253868436 SS(ph)PSVLIHSLGK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPSVLIHSLGK 12 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 S(0.046)S(0.945)PS(0.008)VLIHSLGK 84.352 0.010256 6100700.0 21246.0 17531.0 34477.0 21315.0 29922.0 28645.0 24924.0 22082.0 28760.0 15611.0 True False 20943.02814396078 17490.408046601424 31642.43414506864 22882.576204755595 28162.046788915402 27419.920124756387 26214.442765931373 23108.010334304323 25520.745943773793 18309.340549650024 1.1438439351307548 0.955272419515718 1.728212660595986 1.2497760988553455 1.5381245825073535 1.4975919012703331 1.4317524268470965 1.26208861928378 1.3938648349768998 1.0 14.160292209850045 -5.234275622474466 24.981792717423772 1.4029845732638866 1.049558109469725 0.33623595375806914 0.1890497884680622 743.376811827547 683661.6445009552 0.04464866632258499 0.1180660163642619 5.830749416949072e-06 5.234275622474466 -0.35342646379416154 SS(ph)PTPESR ddPTM_PC-9_AZD4547_30min_R2 1 SSPTPESR 8 0 K7EQ92;Q8NCA9 K7EQ92 ZNF784 Zinc finger protein 784 1 S(0.123)S(0.753)PT(0.123)PESR 101.46 0.0045792 12016000.0 37631.0 35440.0 43780.0 58705.0 51005.0 48999.0 37830.0 44875.0 44565.0 49597.0 True False 49596.87522657528 46895.28693302716 43199.44859465615 45171.4692332087 43923.8361603862 45935.084784092214 41196.796713579344 37940.59987491359 46920.61491874931 47860.62412615191 1.0362772348276723 0.9798302422764004 0.9026093868059524 0.9438127909520133 0.917744742413115 0.9597677761789248 0.8607659734021034 0.7927309885242838 0.980359445273323 1.0 15.546551590003656 -3.1412465739665842 0.7043943252611314 0.9064889655282374 2.2960489227726724 0.271161533964804 0.05807894235420747 30.4576427776434 1.7753864557930283 0.022933330723423764 55.6018323589781 0.0007223595620665344 3.1412465739665842 1.389559957244435 SS(ph)PTPESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPTPESR 8 0 K7EQ92;Q8NCA9 K7EQ92 ZNF784 Zinc finger protein 784 1 S(0.166)S(0.576)PT(0.258)PESR 99.01299999999999 0.0053299 13466000.0 55733.0 61465.0 64502.0 69584.0 71723.0 66945.0 62926.0 64928.0 66940.0 59177.0 True False 65167.4961230739 67566.83899196639 66039.97230519711 65685.43407437176 57669.393017863564 63434.28635006282 56965.19373521208 63223.70879690253 67918.87086196193 69905.32165512576 0.9322251093353711 0.9665478591930933 0.9447059357083263 0.9396342441341934 0.8249642752861147 0.9074314350917738 0.8148906604885802 0.9044191100187391 0.9715836971187417 1.0 16.09311466681282 -6.028965834365035 24.761151935342525 0.8936912347721345 0.9484437525189806 0.11077696948859117 0.05404661827959567 1043.2448403473766 891805.9212912562 0.01565784511255056 0.020256015037658195 9.354792647347151e-07 6.028965834365035 0.054752517746846086 SS(ph)PTQETQAPFIAK ddPTM_PC-9_AZD4547_30min_R2 2 SSPTQETQAPFIAK 14 0 O15231-5 O15231-5 ZNF185 Zinc finger protein 185 1 S(0.225)S(0.775)PTQETQAPFIAK;S(0.226)S(0.773)PT(0.001)QETQAPFIAK 230.57 6.0738e-21 24989000.0 130444.0 114409.0 148135.0 179272.0 168080.0 150843.0 118605.0 178341.0 140366.0 151646.0 True False 171922.47859624727 151389.47186006504 146170.63311031056 137943.6101247898 144744.9932719875 141410.76336428936 129160.61523167025 150782.49631848396 147785.46019713138 146336.9196974504 1.1748400810382962 1.0345268451260334 0.9988636730396976 0.9426439370870068 0.9891214983289647 0.9663368865263409 0.8826249418035318 1.0303790501414458 1.009898667422246 1.0 17.15893427087714 -4.59603367447822 1.4982813374007509 0.9724403301433294 1.3322942122649308 0.7021710649024168 0.0389795402767212 1.007437765845287 1.5029896113632146 0.011379979245310227 0.6145797395416926 2.5349320684235437e-05 4.59603367447822 0.3598538821216014 SS(ph)PTQETQAPFIAK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPTQETQAPFIAK 14 0 O15231-5 O15231-5 ZNF185 Zinc finger protein 185 1 S(0.382)S(0.618)PTQETQAPFIAK 176.56 0.00010034 13432000.0 67963.0 53977.0 65838.0 57307.0 68233.0 53762.0 55604.0 60234.0 67682.0 50874.0 True False 66993.83515711235 53852.01957283702 60425.053782029456 61521.54795054785 64219.669091239346 51462.724585343145 58482.9030475385 63032.69153502792 60058.94043694352 59667.50311465604 1.1227859665650521 0.9025351617170223 1.0126962019161037 1.0310729415361843 1.076292215007488 0.8624916730042024 0.9801466459080542 1.0563990152881946 1.006560310082614 1.0 15.864657785745543 SS(ph)PTSASACGAQGLR ddPTM_PC-9_AZD4547_30min_R2 1 SSPTSASACGAQGLR 15 0 Q8IVL0-3;Q8IVL0-2;Q8IVL0;H0YHA8;A0A2R8YFX5 Q8IVL0-3 NAV3 Neuron navigator 3 1 S(0.101)S(0.867)PT(0.024)S(0.008)ASACGAQGLR 90.476 0.019832 0.0 8254.7 10347.0 10771.0 17825.0 15434.0 12831.0 12392.0 12165.0 12107.0 11165.0 True False 10879.522891573724 13691.465403386901 10628.169502353616 13715.721643504727 13291.255510232353 12028.675541637318 13494.86399351507 10285.17877389022 12746.951303069629 10774.116748361515 1.0097832746455284 1.270773811270334 0.9864539015664467 1.2730251549938476 1.233628316887659 1.116441915618428 1.2525262449534265 0.9546192058346081 1.183108704015866 1.0 13.395281982971602 -7.758322894556586 24.999999983718038 1.0516479770097884 1.1657007985864858 0.18960816762149524 0.11087916297331149 132.69257480721276 1064467.9662161535 0.05133743448857057 0.027997702484141844 1.744524630188914e-08 7.758322894556586 0.11405282157669738 SS(ph)PTSASACGAQGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPTSASACGAQGLR 15 0 Q8IVL0-3;Q8IVL0-2;Q8IVL0;H0YHA8;A0A2R8YFX5 Q8IVL0-3 NAV3 Neuron navigator 3 1 S(0.473)S(0.518)PT(0.007)S(0.002)ASACGAQGLR 108.37 0.0038485999999999998 0.0 8967.1 10411.0 11548.0 12859.0 10117.0 8915.2 10132.0 8158.6 10316.0 7880.2 True False 10485.052921701963 11444.535276097988 11823.348116033885 12138.551919440491 8134.646475492169 8447.671217687359 9172.223610672363 7944.445394751247 10466.851984045401 9308.817880371123 1.126357079539722 1.2294294961157537 1.2701234751799133 1.3039842518604041 0.8738646066591494 0.9074912976330103 0.9853263570676587 0.8534322506731131 1.124401843344271 1.0 13.18438225734327 -6.260699724669027 24.99907935339854 0.948989944880892 1.2349454261599577 0.7240907971202835 0.08307505935556486 33.72408653237279 1139817.9657725168 0.024683552549398375 0.03001231101685424 5.486561799048352e-07 6.260699724669027 0.2859554812790658 SS(ph)PVEFECINEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPVEFECINEK 12 0 O75131;H0YB26 O75131 CPNE3 Copine-3 1 S(0.247)S(0.753)PVEFECINEK 153.81 0.00023464 5509700.0 16472.0 16730.0 17557.0 17450.0 19292.0 13749.0 15341.0 11296.0 17225.0 14203.0 True False 19260.384263170345 18390.84383528184 17975.62546529328 16472.333073663307 15511.871088780761 13027.978236268787 13887.78942077819 10999.491969101327 17476.88303850156 16777.891469113863 1.1479621440290313 1.0961355823011034 1.071387635233206 0.981788033614769 0.9245423429598589 0.776496752303576 0.827743429282755 0.6555944165779178 1.0416614668580053 1.0 14.03427379865306 -6.028800196804026 1.4004708107609176 0.8383604648957433 1.121391806372605 0.5026550287976008 0.10448557550769592 0.3120689208944087 1.239095940019634 0.03619029959139578 0.06314640436723211 9.358361195017944e-07 6.028800196804026 0.2830313414768616 SS(ph)PVEFECINEK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPVEFECINEK 12 0 O75131;H0YB26 O75131 CPNE3 Copine-3 1 S(0.226)S(0.774)PVEFECINEK 209.67 3.5516e-08 7479900.0 31130.0 33996.0 35615.0 27329.0 38438.0 37982.0 39031.0 32881.0 28609.0 30017.0 True False 30686.080491457175 33917.284350707996 32686.872177875674 29338.865826871464 36177.15241201559 36357.59840036646 41051.83419985028 34408.771297992025 25386.75315387427 35205.39845486162 0.8716299726248273 0.9634114607222761 0.9284619294903007 0.8333626976126433 1.0276024132605657 1.0327279336713695 1.1660664557591822 0.977372017024861 0.7211039859816879 1.0 15.1035090506532 -6.279327883008914 24.353167009763023 0.9975392434588164 0.9058908181411978 0.13215003383173962 0.1084550160427948 1263.8641866645448 1720602.784576872 0.035483339364420496 0.040329137678323364 5.256202845241721e-07 6.279327883008914 -0.09164842531761863 SS(ph)PVESLKK ddPTM_PC-9_Lapatinib_30min_R1 2 SSPVESLKK 9 1 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2;B1AKL5 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 S(0.06)S(0.94)PVESLKK;S(0.419)S(0.581)PVESLKK 90.10799999999999 0.012968 63324500.0 186455.0 173366.0 167516.0 146997.0 188877.0 157032.0 168159.0 168249.0 185881.0 149127.0 True False 183796.11750834098 172964.581678575 153743.48111045995 157807.64974761708 177767.6262064693 150316.10741947097 176865.45021169368 176066.46276317208 164945.12436629395 174903.4032507633 1.0508435747521045 0.9889149008186617 0.8790193801434163 0.9022560271246659 1.0163760275813472 0.8594235711008954 1.0112178889859411 1.006649724881232 0.9430641216844025 1.0 17.416198835767453 SS(ph)PVGGGPR ddPTM_PC-9_AZD4547_30min_R2 1 SSPVGGGPR 9 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 S(0.224)S(0.776)PVGGGPR 107.45 0.0025013 77391000.0 27073.0 23869.0 31090.0 46650.0 36062.0 36537.0 41978.0 35651.0 38511.0 34509.0 True False 35681.65084661773 31584.187466264808 30677.726286154877 35895.56323531531 31055.41377543081 34252.335614122254 45713.960677838586 30141.9571284801 40546.61283823526 33300.85041372211 1.0714936826932977 0.9484498766208708 0.9212295153133286 1.0779173141033063 0.9325711923150757 1.0285723994606477 1.3727565545593836 0.905140762292955 1.2175849065262137 1.0 15.023271399848802 -7.015726993903403 24.897035198439035 1.1280654520208029 0.988186233137507 0.2016264846934439 0.12575001255969148 1021.8347712126729 1617639.6591305665 0.0444254957690898 0.03549869837358836 9.64435096076106e-08 7.015726993903403 -0.1398792188832959 SS(ph)PVGGGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSPVGGGPR 9 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 S(0.181)S(0.819)PVGGGPR;S(0.223)S(0.777)PVGGGPR;S(0.226)S(0.774)PVGGGPR 132.88 0.0011875 142806200.0 65449.5 85583.0 99388.0 94176.0 118701.0 98039.0 105112.0 93363.0 83233.0 66809.0 True False 76528.80766345121 94079.11464165714 101757.78685108895 88899.62404271142 95442.39115225813 92897.66225220422 95155.03041502112 90912.3201762755 84450.12516363444 78920.94284024702 0.9696894754331812 1.1920677991910655 1.2893635477349608 1.1264389507188657 1.209341750331773 1.177097724747778 1.2057006288892846 1.151941638106144 1.0700597601143675 1.0 16.26812057107498 -8.412134607367284 2.25399173294573 1.0017434518695199 1.1736346374855724 0.32796595406389595 0.07748454376597202 0.32122729451206333 3.3619618530742157 0.07309457832297159 0.020343286650512767 3.871376349820788e-09 8.412134607367284 0.17189118561605254 SS(ph)PVLQHK ddPTM_PC-9_AZD4547_30min_R2 2 SSPVLQHK 8 0 A0A2R8Y4C6;A0A2R8YCU9;A0A2U3TZV9;A0A2R8Y7B1;H7C2C6;A0A2R8Y820;A0A2R8Y4Z5;A0A2R8Y885;A0A2R8Y7D4;A0A2R8YDS8;H0Y470;H0Y7U8;A0A2R8Y5D7;H0Y7K3;Q3V6T2-5;Q3V6T2-4;Q3V6T2-2;Q3V6T2-3;Q3V6T2 A0A2R8Y4C6 CCDC88A Girdin 1 S(0.223)S(0.777)PVLQHK;S(0.203)S(0.797)PVLQHK 132.32 0.0020034000000000002 29605000.0 69200.0 71300.0 114352.0 149474.0 135000.0 132789.0 113189.0 117156.0 109353.0 121473.0 True False 91204.16055058358 94346.33065250659 112835.61776373051 115015.0786502791 116257.58026962343 124485.68283831929 123262.60172385201 99052.23217705592 115133.17633142573 117220.26724350385 0.7780579476168866 0.8048636372455898 0.9625947834544257 0.981187650863789 0.991787367521688 1.0619808823650168 1.0515468410236286 0.845009438267982 0.9821951360361381 1.0 16.838862506004283 -5.261505206740641 3.0979500060483027 0.98675208983765 0.780189855208586 0.6669673526716167 0.05497545077183017 0.15864639538482847 3.0930643134766775 0.015920033485760415 0.0463155578223769 5.4763953529220045e-06 5.261505206740641 -0.20656223462906398 SS(ph)PVNRPSSATNK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPVNRPSSATNK 13 1 Q96L91-5;Q96L91-2;Q96L91;Q96L91-4;Q96L91-3;A0A0A0MR80;A0A0A0MR72 Q96L91-5 EP400 E1A-binding protein p400 1 S(0.246)S(0.743)PVNRPS(0.003)S(0.004)AT(0.004)NK 53.981 0.039412 17871000.0 17448.0 17170.0 24312.0 16229.0 19030.0 18693.0 16275.0 16813.0 21783.0 11035.0 True False 17199.18832042867 17130.243919921653 22313.161207033954 17422.53479835695 17910.692814419497 17893.543965511297 17117.639865813402 17594.19335887413 19329.5691548409 12942.385046786754 1.3289040820724745 1.3235770577058077 1.7240378126884512 1.3461610619197655 1.383878840698395 1.3825538261167545 1.3226031990188123 1.3594243483925936 1.4935090468228585 1.0 13.659815883904969 -11.556393795376186 2.5472774602307773 0.5046451782371693 1.4069465880909964 0.5245044236371799 0.11630786590863239 2565468.622320953 1637546.3286915491 7404187.97866974 0.029704463689564958 2.77719391246614e-12 11.556393795376186 0.9023014098538271 SS(ph)PVPVSDTQK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPVPVSDTQK 11 0 Q76FK4-2;Q76FK4-4;Q76FK4;F8WE42;F5H101;F5GWN9 Q76FK4-2 NOL8 Nucleolar protein 8 1 S(0.394)S(0.606)PVPVSDTQK 91.12299999999999 0.022817 0.0 19166.0 23867.0 18289.0 21387.0 27107.0 27315.0 28985.0 22717.0 21981.0 19280.0 True False 18892.689325386065 23811.737427884094 16785.349017581593 22959.87132494053 25512.619554412482 26146.80112437498 30485.701475305774 23772.514752485786 19505.268309808474 22612.522311014847 0.8354967688050968 1.0530332308963646 0.7423032595264809 1.0153609141496118 1.1282518245204765 1.1562974163054132 1.3481778395175226 1.051298675376249 0.8625870233108498 1.0 14.464834305855318 -5.994519401541582 24.178827026174783 1.1063284246617247 0.8919330338916249 0.3244317074317744 0.13665282574988363 118.60110810841572 523220.55388358905 0.03990505420872535 0.05895219323711647 1.0126995067695857e-06 5.994519401541582 -0.21439539077009973 SS(ph)PVVNDGVVR ddPTM_PC-9_AZD4547_30min_R2 1 SSPVVNDGVVR 11 0 H0Y8R1;F5H5I6;H0YAK1;Q12849-5;Q12849;H0YAM1 H0Y8R1 GRSF1 G-rich sequence factor 1 1 S(0.227)S(0.773)PVVNDGVVR 133.88 5.6067e-05 5826000.0 10761.0 10001.0 15026.0 19680.0 18409.0 14920.0 12384.0 14428.0 14341.0 17121.0 True False 14182.774157295216 13233.627669785685 14826.745422186015 15143.080052969033 15853.228112470339 13987.05004140198 13486.152009013118 12198.484122456899 15099.03598226823 16521.599001226823 0.8584383482641156 0.8009895209781458 0.8974158869904205 0.9165626191414387 0.9595456294086998 0.8465917881412909 0.8162740185142912 0.7383355643452605 0.913896771199146 1.0 14.012065700659372 -12.014630768180135 1.3819294489778777 1.6722672174346715 0.8594064782910198 0.31514563369656146 0.06148505948004166 210477.08388277242 16110.848659291953 437991.41100567614 0.01880253721355277 9.668725527884973e-13 12.014630768180135 -0.8128607391436518 SS(ph)PVVNDGVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPVVNDGVVR 11 0 H0Y8R1;F5H5I6;H0YAK1;Q12849-5;Q12849;H0YAM1 H0Y8R1 GRSF1 G-rich sequence factor 1 1 S(0.141)S(0.859)PVVNDGVVR 134.18 5.9093999999999994e-05 4558400.0 20190.0 21066.0 26704.0 22973.0 29335.0 25096.0 22125.0 21933.0 20438.0 18537.0 True False 23607.76822932306 23157.29325965614 27340.72463548396 21685.897289470915 23587.01733305948 23779.921581016908 20029.159828871485 21357.28198993444 20736.86708510274 21897.611361188752 1.078097872865046 1.057525995766828 1.248571096843127 0.990331636258141 1.0771502399967252 1.0859596139862249 0.9146732718241176 0.9753247346323813 0.9469921966857393 1.0 14.418485885662957 -7.247957684680359 23.69199578438955 0.9571912831073619 1.090294942429932 0.5014324190980097 0.06366424991015435 323.634507342495 568738.2862312373 0.02433145255301275 0.018718306746559037 5.6499202191584936e-08 7.247957684680359 0.13310365932257007 SS(ph)PVVNDGVVR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPVVNDGVVR 11 0 H0Y8R1;F5H5I6;H0YAK1;Q12849-5;Q12849;H0YAM1 H0Y8R1 GRSF1 G-rich sequence factor 1 1 S(0.232)S(0.768)PVVNDGVVR 113.52 0.0015527000000000002 5869600.0 22566.0 26172.0 23194.0 18832.0 19221.0 16134.0 16635.0 14629.0 24500.0 14646.0 True False 22244.20470190241 26111.400342002882 21287.078851429138 20216.9681017104 18090.458569939958 15443.986430190946 17496.278904319883 15308.71674579014 21740.552003562494 17177.5415854317 1.294958570833428 1.5200894849905648 1.2392389647586557 1.176941880836804 1.0531459627076383 0.899080136315258 1.018555467748569 0.8912053374840022 1.2656381529008023 1.0 14.068235955240302 -5.822945405788571 1.5847226952200697 1.0083562230588385 1.405931393804529 0.6409033399992679 0.113246926680826 0.2238855175682157 1.1440941082679583 0.03574814063523794 0.07362338475269456 1.5033309346629882e-06 5.822945405788571 0.3975751707456905 SS(ph)PYGTLKPEEMSGPGLAEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPYGTLKPEEMSGPGLAEPK 21 1 Q5JSZ5;A0A494C0D3;Q5JSZ5-5;A0A494C065;H0Y412 Q5JSZ5 PRRC2B Protein PRRC2B 1 S(0.109)S(0.418)PY(0.341)GT(0.132)LKPEEMSGPGLAEPK 59.181999999999995 0.018011000000000003 22715000.0 61043.0 61445.0 54531.0 81847.0 84034.0 88397.0 98402.0 84793.0 83688.0 68568.0 True False 71376.37424579343 67544.85352414192 55831.22584996917 77261.37794155422 67568.14094311636 83761.30570597516 89080.65019121428 82567.2735956098 84911.77867785878 80998.8356160106 0.8812024728869663 0.8338990679366098 0.6892843017478304 0.9538578839308942 0.8341865710691837 1.0341050592759202 1.0997769228871013 1.019363710202387 1.04830863347713 1.0 16.305613548496325 -6.772225752278048 6.188238825128462 1.0463150400371677 0.8357573231962091 0.7014727270004637 0.06578600067353059 0.08744742547005174 12.627883890527698 0.023106698636421202 0.021326908738430173 1.6895624454123855e-07 6.772225752278048 -0.2105577168409586 SS(ph)PYGTLKPEEMSGPGLAEPK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPYGTLKPEEMSGPGLAEPK 21 1 Q5JSZ5;A0A494C0D3;Q5JSZ5-5;A0A494C065;H0Y412 Q5JSZ5 PRRC2B Protein PRRC2B 1 S(0.148)S(0.693)PY(0.117)GT(0.042)LKPEEMSGPGLAEPK 82.755 0.00092218 14281000.0 40478.0 37971.0 38935.0 34022.0 40794.0 38173.0 38807.0 39223.0 37656.0 39041.0 True False 39900.77629724392 37883.08048243128 35733.9145934463 36524.09137406495 38394.5771240898 36540.429775609206 40816.236575890696 41045.44377060131 33414.78474474081 45789.18483113748 0.8714017610138949 0.8273368617968953 0.7804007589396217 0.797657602090088 0.8385075485768594 0.7980144200069063 0.8913946978181387 0.8964004037628044 0.729752776075152 1.0 15.482719260993674 -7.2606521675310045 24.98896801167154 0.8707536697871966 0.8174481648590773 0.1637904761330955 0.06577522007651432 147.86059988300764 4693742.508080739 0.025237932815904394 0.01835242965404195 5.4871626343671545e-08 7.2606521675310045 -0.05330550492811925 SS(ph)PYHSQLDVR ddPTM_PC-9_AZD4547_30min_R2 2 SSPYHSQLDVR 11 0 O94929 O94929 ABLIM3 Actin-binding LIM protein 3 1 S(0.212)S(0.787)PYHSQLDVR;S(0.042)S(0.933)PY(0.024)HS(0.001)QLDVR 118.76 0.0010316 9310800.0 16179.3 13101.8 24559.9 26432.0 25504.0 30569.0 19200.5 30546.0 25757.0 22649.5 True False 21323.98084965397 17336.700630336763 24234.219678846428 20338.51077032916 21963.209831085 28657.51559756146 20909.30730370288 25825.81757725036 27118.462436042322 21856.54789897126 0.9756335240231437 0.7932039730369663 1.1087853301841448 0.9305454303369861 1.0048800905159758 1.3111638548789448 0.956661015287187 1.1816055168742325 1.2407477411983585 1.0 14.415777934158555 -6.539855630999181 24.970435127299073 1.1402692052699428 0.9538699532934509 0.3526991783481954 0.12051018341689461 260.71631101169265 383471.6185629518 0.038381470404723395 0.03838993867502915 2.884990377751636e-07 6.539855630999181 -0.18639925197649188 SS(ph)PYHSQLDVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPYHSQLDVR 11 0 O94929 O94929 ABLIM3 Actin-binding LIM protein 3 1 S(0.209)S(0.701)PY(0.003)HS(0.087)QLDVR 69.229 0.035238 4203600.0 6142.1 7563.4 9599.8 10614.0 9889.8 9377.7 8781.0 8202.2 6864.5 6955.0 True False 7181.836217995298 8314.244367230764 9828.69563944424 10019.33199105228 7951.964684523321 8885.916903502644 7949.200111065342 7986.900940949262 6964.8803261418825 8215.886444250289 0.8741401511240886 1.0119716750770464 1.1963037349819556 1.2195071169787277 0.9678766543917281 1.0815530331144318 0.967540163195466 0.9721289352214358 0.8477332754539352 1.0 13.004200526268399 -7.43303574599339 1.6757035741973687 0.9269591936345708 1.0691695383220265 0.2196636596018221 0.10205680366996964 0.5882090015481967 3.2105443781488603 0.06679723853960427 0.03526052349738856 3.689472299411134e-08 7.43303574599339 0.14221034468745575 SS(ph)PYHSQLDVR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPYHSQLDVR 11 0 O94929 O94929 ABLIM3 Actin-binding LIM protein 3 1 S(0.435)S(0.515)PY(0.05)HSQLDVR 68.809 0.020564 3337500.0 11187.0 11581.0 17712.0 10193.0 17204.0 10956.0 11944.0 9756.2 13907.0 9355.6 True False 11027.471328555448 11554.184906034514 16255.787730297183 10942.627222851217 16192.094544365378 10487.437419683401 12562.401877559161 10209.508668759156 12340.6472127977 10972.702994446603 1.004991325668485 1.052993497762785 1.4814752334519947 0.9972590371205156 1.4756705392062797 0.9557752018797192 1.1448776007076034 0.9304460964564786 1.1246679345138046 1.0 13.421631339778674 SS(ph)QKSPELGK ddPTM_PC-9_Lapatinib_30min_R1 1 SSQKSPELGK 10 1 Q9UEG4 Q9UEG4 ZNF629 Zinc finger protein 629 1 S(0.056)S(0.906)QKS(0.037)PELGK 59.11600000000001 0.034895999999999996 26849000.0 202930.0 148800.0 144620.0 154460.0 156230.0 163270.0 137560.0 132060.0 176180.0 109210.0 True False 200036.18098719616 148455.4627422444 132729.90184934367 165819.50366345525 147040.858559998 156287.32270095905 144682.1837137508 138195.98970873232 156336.75314235262 128086.80298682184 1.5617235837151529 1.1590223136221003 1.0362496272391117 1.2945869503864151 1.1479782079901413 1.2201672542099329 1.1295635486244149 1.078924498747545 1.220553167826644 1.0 16.966762314314202 -4.762045810491562 7.015692496657072 1.1484542511095752 1.5703794203937957 0.6878974909345614 0.0845690237577264 0.05967594809889621 17.169582601866523 0.019998582162196882 0.12029965164693716 1.7296339033890177e-05 4.762045810491562 0.4219251692842205 SS(ph)S(ph)T(ph)LS(ph)Y(ph)HKK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSTLSYHKK 10 1 O43345 O43345 ZNF208 Zinc finger protein 208 5 S(0.196)S(0.915)S(0.915)T(0.988)LS(0.987)Y(1)HKK 57.019 0.0301 0.0 7178.8 8824.5 9507.3 9286.0 12313.0 10398.0 12455.0 11355.0 12300.0 11131.0 True False 7076.428995569309 8804.067412425667 8725.646493239292 9968.923417187907 11588.7735482894 9953.301778921876 13099.85895721695 11882.594753465513 10914.644475257915 13054.978518874797 0.5420483063482837 0.6743839064688469 0.6683769322656343 0.7636108633020657 0.8876899744824882 0.7624142593977815 1.0034378025423223 0.9101964232484749 0.8360522738109142 1.0 13.67231246334051 -4.088536232858944 0.3048469868502672 0.9707670029827231 2.603351813461721e-18 0.8047103727903565 0.06322131596178364 4.973072058045119 0.2712816531895805 0.06775637688216496 1.936290648713196 8.155747415127633e-05 4.088536232858944 -0.9707670029827231 SS(ph)SEITLSECDAEDAGEPR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSEITLSECDAEDAGEPR 19 0 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 S(0.008)S(0.496)S(0.496)EITLSECDAEDAGEPR;S(0.008)S(0.934)S(0.058)EITLSECDAEDAGEPR 450.52 0.0 81846000.0 22986.0 26642.0 29507.0 27228.3 31312.0 26887.0 26767.0 26423.0 24483.0 21568.0 True False 22658.21542488385 26580.312085879596 27081.048360313856 29230.760012946095 29470.289721760564 25737.105686658248 28152.864288063138 27650.709041903945 21725.46672258044 25296.000062446477 0.8957232514606691 1.0507713480495977 1.0705664252633125 1.1555487010114702 1.1650177754984705 1.0174377618249069 1.1129373900444386 1.0930862181232037 0.8588498841298344 1.0 14.626621655919852 -8.248132833458067 24.703192264754875 0.9294249410960916 1.0751848723361987 0.3353102778847826 0.07899002685213327 652.8095783445964 1211927.4886335083 0.05507185324255032 0.020536527588473935 5.64764209419272e-09 8.248132833458067 0.1457599312401071 SS(ph)SENDVELLTKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSENDVELLTKK 13 1 Q9C0D6 Q9C0D6 FHDC1 FH2 domain-containing protein 1 1 S(0.016)S(0.801)S(0.183)ENDVELLTKK 58.98 0.028988 2458000.0 9172.7 8363.6 10541.0 12681.0 12998.0 15956.0 11992.0 12819.0 12666.0 9724.2 True False 10725.456940916867 9193.882934893194 10792.337416965116 11970.524682356696 10451.135206923724 15119.23927106734 10856.030945438506 12482.514832853216 12851.21628828219 11487.120483275161 0.9336941278306213 0.8003644558511561 0.9395163420352712 1.0420822781292627 0.9098133185022482 1.3161905364430029 0.9450611196465207 1.0866530782041777 1.118750021556151 1.0 13.487729577434468 -5.833104203710013 1.344746365749795 1.0784107314144251 0.8623502666738051 0.34647878870332705 0.10893110053286209 0.47496104064988415 1.7319581691729755 0.03652449831797913 0.0814988885250146 1.4685738688236863e-06 5.833104203710013 -0.21606046474062002 SS(ph)SESYTQSFQSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSESYTQSFQSR 13 0 Q9BTU6;E9PAM4 Q9BTU6 PI4K2A Phosphatidylinositol 4-kinase type 2-alpha 1 S(0.008)S(0.652)S(0.337)ES(0.004)YTQSFQSR 255.39 8.9732e-44 18872000.0 56461.0 52778.0 36640.0 27529.0 40508.0 31929.0 29788.0 37386.0 51062.0 21651.0 True False 55655.85578632072 52655.79578367063 33627.60063449013 29553.57449405192 38125.399081792195 30563.471100134284 31330.27688619662 39123.09004430307 45310.85985330242 25393.346501855933 2.1917495507042752 2.07360600462102 1.3242681752100842 1.1638314190645147 1.5013932519294262 1.2036015457001887 1.2337986599720827 1.5406827155075313 1.7843595309499978 1.0 14.632162914884862 -5.234320154015059 5.327180148543631 1.3523904351248954 2.1496894009886156 0.6910681301283081 0.2111103766324429 0.10198342118223824 8.708672976184648 0.05526098863850515 0.14478326900468438 5.83015157618997e-06 5.234320154015059 0.7972989658637202 SS(ph)SFAGGR ddPTM_PC-9_AZD4547_30min_R2 1 SSSFAGGR 8 0 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 SS(0.5)S(0.5)FAGGR 126.24 0.0035068000000000005 4203800.0 21032.0 23698.0 29040.0 27696.0 29332.0 29354.0 21490.0 32964.0 30220.0 29797.0 True False 27719.738507223585 31357.915060352047 28654.910625601064 21311.115098934468 25259.75810717476 27518.489739632292 23402.568368353677 27870.171237362705 31817.36750464725 28753.81609950095 0.9640368572749093 1.0905653340704329 0.9965602661727533 0.7411578005920523 0.8784836774278865 0.9570378291495681 0.8138943466623845 0.9692686056320162 1.1065441677217749 1.0 14.811465817431742 -10.178253013873208 7.744816955803513 0.999999675259535 0.941164812873854 0.020039412681621016 0.10697378673794668 0.0 0.0 0.11028717265631068 0.026748568353688287 6.63356495617027e-11 10.178253013873208 -0.05883486238568103 SS(ph)SFGSVSTSSNSSK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSFGSVSTSSNSSK 15 0 E5RG30;E5RJ65;E5RHF1;E5RGS8;E5RH07;E5RGQ6;A0A0C4DGW2;P57768-2;P57768 E5RG30 SNX16 Sorting nexin-16 1 S(0.001)S(0.834)S(0.165)FGSVSTSSNSSK 333.59 2.0092999999999994e-181 18937000.0 110100.0 93984.0 94760.0 100200.0 100110.0 105780.0 90083.0 100480.0 126390.0 93275.0 True False 108529.95381013301 93766.38582235962 86969.19858417795 107569.04225740106 94221.72662383264 101256.03598522375 94747.0569604958 105148.6676202742 112154.62725429656 109397.45946887488 0.9920701480367679 0.8571166668549326 0.7949837135744631 0.9832864746553458 0.8612789280599341 0.9255794099499406 0.8660809622133198 0.9611618782627258 1.025203215859013 1.0 16.739219709329497 -7.9713045255905515 4.074867373143467 1.0091603714290267 0.8949688044711855 0.40562464918755303 0.05659349218390872 0.20352106235384457 7.486392122026491 0.03555644404201286 0.014774984355977877 1.0683055248793106e-08 7.9713045255905515 -0.11419156695784116 SS(ph)SKGSVEEIMSQPK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSKGSVEEIMSQPK 15 1 A0A087WVA8;Q8IWB9;Q8IWB9-2;J3KRZ8 A0A087WVA8 TEX2 Testis-expressed sequence 2 protein 1 S(0.045)S(0.461)S(0.461)KGS(0.033)VEEIMSQPK 73.156 0.02768 4895800.0 51808.0 46246.0 33244.0 31360.0 27420.0 24009.0 25321.0 24369.0 30237.0 17473.0 True False 51069.20841957642 46138.920228345785 30510.80664555102 33666.31901389328 25807.209509794156 22982.19103771255 26631.99748339546 25501.272703408285 26831.39065027428 20493.184768690986 2.4920093677971797 2.2514275233020764 1.488826992482141 1.6428056153247543 1.259306925745471 1.1214553178100561 1.2995538655408607 1.2443782160383652 1.3092835961381004 1.0 14.322856585126512 -4.977714564698193 0.8205806927223651 1.2065403520722746 3.1002951317768463 0.9173094982298002 0.1336820512486331 0.487897658090182 0.3077799383253045 0.05014826742150577 0.7968944620236983 1.0526534915220458e-05 4.977714564698193 1.8937547797045717 up SS(ph)SLDMNR ddPTM_PC-9_AZD4547_30min_R2 1 SSSLDMNR 8 0 H0YDT0;Q96D71-4;E9PMG1;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 S(0.019)S(0.614)S(0.367)LDMNR 91.265 0.0088545 23087000.0 80380.0 62060.0 65518.0 104700.0 92574.0 79184.0 64122.0 79197.0 46872.0 84441.0 True False 105939.16799213726 82119.68135055482 64649.18851129929 80563.03259887498 79721.69804355652 74232.61196235742 69828.7337792264 66958.92341601186 49349.55822891549 81484.74629184004 1.300110423277419 1.007792072597744 0.7933900693481489 0.9886885124528226 0.9783634566159277 0.911000099288413 0.8569546689037076 0.821735680150448 0.6056294027371526 1.0 16.314242395840886 SS(ph)SLDMNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSLDMNR 8 0 H0YDT0;Q96D71-4;E9PMG1;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 S(0.001)S(0.588)S(0.411)LDMNR 108.43 0.0037941000000000003 7381400.0 38330.0 28383.0 45539.0 45546.0 45991.0 37600.0 40629.0 39296.0 41860.0 29518.0 True False 44818.51194799168 31200.67666328778 46624.82246761925 42994.20528212431 36979.39369915594 35628.18980898298 36780.32699151277 38264.5216375536 42472.1233086604 34869.37973564056 1.285325758237734 0.8947872574686798 1.3371279564219851 1.23300745835118 1.0605119442763904 1.0217615018992385 1.0548030183031616 1.0973674303257768 1.218034953034996 1.0 15.089673080908854 -6.27620028542791 24.451468978553535 1.0765684189366038 1.1773328945469452 0.16539194278380442 0.12254471127045118 1272.1407987732143 2107298.4113656846 0.03799481233609605 0.04326253066676203 5.294192330713194e-07 6.27620028542791 0.10076447561034141 SS(ph)SLEGFHNHFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSLEGFHNHFK 12 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 S(0.052)S(0.474)S(0.474)LEGFHNHFK 130.15 0.00013314 7363300.0 60173.0 70506.0 105250.0 134470.0 165480.0 204990.0 162890.0 167560.0 167500.0 154410.0 True False 70359.10042907656 77505.3697220791 107759.55916284783 126936.081857622 133055.38190811963 194239.96353572898 147459.8799785255 163161.7275444954 169949.37062113278 182403.3106911128 0.3857336808333745 0.42491207768333217 0.5907763337987383 0.6959088701661745 0.7294570553789979 1.0648927522190688 0.8084276509006926 0.8945107790329438 0.931723059067333 1.0 17.476772389653853 -5.764306649443309 0.818318124452842 0.9340929616501235 0.32915000669761396 0.8784255139242592 0.07686536599258005 0.2802828064009335 0.33555385404544663 0.03520874126189911 0.12022712170336468 1.7206532160637375e-06 5.764306649443309 -0.6049429549525095 down SS(ph)SLEGFHNHFK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSLEGFHNHFK 12 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 S(0.197)S(0.705)S(0.098)LEGFHNHFK 104.7 0.0014357999999999999 0.0 56460.0 42477.0 76006.0 55543.0 64409.0 94530.0 60974.0 59626.0 123100.0 103530.0 True False 55654.87004650409 42378.6471162791 69757.08007164457 59627.81750601636 60620.58925296613 90487.17226019273 64130.93537192668 62396.441635414725 109235.18169953249 121425.02255494616 0.4583476195882084 0.3490108235071753 0.5744868611416458 0.4910669666874809 0.49924297296740994 0.7452102569653326 0.5281525506236305 0.5138680670796635 0.8996101413125319 1.0 16.889706228782025 -9.456134971919177 0.15952135106502383 1.3500148738742432 0.2720824224560484 0.7021843146374753 0.1076082130681814 7.53852168610159 0.4361546029460138 2.010294334133977 0.7369466149852639 3.4983642645272003e-10 9.456134971919177 -1.077932451418195 down SS(ph)SLGSNR ddPTM_PC-9_AZD4547_30min_R2 1 SSSLGSNR 8 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 S(0.108)S(0.367)S(0.361)LGS(0.163)NR 88.134 0.029526999999999998 0.0 70872.0 60083.0 101330.0 125070.0 124170.0 125020.0 109630.0 123350.0 121880.0 130160.0 True False 93407.82177082317 79503.65476289712 99986.29799215407 96237.04381223775 106931.13883021566 117202.47963646622 119386.85761854898 104289.09180101598 128322.32797704842 125603.1380176207 0.743674268374721 0.6329750674839322 0.7960493628600833 0.766199358798956 0.8513413002087131 0.9331174482282762 0.9505085581683504 0.8303064194652955 1.0216490607029758 1.0 16.938512982821656 -6.176351397961596 0.6798793485957307 0.9602855944714106 0.6686271966727295 0.7595440441672742 0.057528398684717416 0.42175332160894746 0.4054639860404767 0.034843625045995606 0.07215396089176784 6.662674582620057e-07 6.176351397961596 -0.2916583977986811 SS(ph)SLGSNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSLGSNR 8 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 S(0.173)S(0.654)S(0.173)LGSNR;S(0.213)S(0.725)S(0.059)LGS(0.003)NR 83.883 0.036858999999999996 0.0 45524.0 54495.0 75774.0 77522.0 106750.0 106220.0 86148.0 88594.0 92987.0 88275.0 True False 53230.31406001498 59904.90345509167 77580.73953449541 73178.69366971504 85833.10381128688 100649.63621037695 77987.4377824914 86268.50137310216 94346.75896087907 104278.5587154843 0.510462694495516 0.5744699983679042 0.7439759475978974 0.7017616523582498 0.8231136378234345 0.9651997251418811 0.7478760614180896 0.8272889694273476 0.9047570288950451 1.0 16.67008302237312 -4.253682066602157 0.3833428880468346 0.9132171898006511 1.1187988685316026e-19 0.7910322322233964 0.06867637773831431 4.239673388519811 0.362258115912158 0.05941287726274366 1.9283022431688004 5.575937965213785e-05 4.253682066602157 -0.9132171898006511 SS(ph)SLGSNR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSLGSNR 8 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 S(0.171)S(0.578)S(0.251)LGSNR 82.831 0.015913999999999998 18938000.0 184280.0 192430.0 262120.0 253570.0 304630.0 275780.0 274600.0 293600.0 284550.0 250340.0 True False 181652.1334071871 191984.44015786418 240569.50541245978 272218.3836847236 286712.26232562354 263985.5322745789 288817.44437188125 307241.727839496 252500.98255566158 293610.9354429184 0.6186831329465333 0.6538736027261776 0.8193479069488864 0.9271397990475945 0.9765040320896493 0.8990997963899098 0.9836740036136391 1.0464246754842943 0.8599849395076462 1.0 18.16354617632185 -5.426508384683229 1.607703921834684 0.9626541806427047 0.6043685983160644 0.8731465484271081 0.04886357940543327 0.13784409848470755 0.6496625786082401 0.014444958136904235 0.05162311245040723 3.7453431603952123e-06 5.426508384683229 -0.3582855823266403 SS(ph)SLIQLTSQNSSPNQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSLIQLTSQNSSPNQQR 18 0 H7C419;O95639 H7C419 CPSF4 Cleavage and polyadenylation specificity factor subunit 4 1 S(0.052)S(0.474)S(0.474)LIQLTSQNSSPNQQR;S(0.015)S(0.492)S(0.492)LIQLTSQNSSPNQQR 222.96 5.441799999999998e-82 6796300.0 16985.7 15571.099999999999 15286.3 16654.6 22297.0 16746.8 18941.6 23359.0 15663.2 14579.0 True False 19861.043527132857 17116.895902185108 15650.783365615576 15721.496756941713 17928.06291035376 15868.568326943505 17147.31452269163 22745.85100090631 15892.244668136873 17222.057292699497 1.1532329262167789 0.9938937962679425 0.9087638659900411 0.9128698441623535 1.0409942671572427 0.921409565491938 0.995660055663643 1.3207394804422334 0.9227843339525796 1.0 14.071969872382432 -7.558908122096155 24.999997672487968 1.1046971134467412 0.9819615348532496 0.10281734492573746 0.11725497113340996 291.5099799188269 202269.31299874358 0.05271316071435948 0.030434060876423995 2.7611619367198683e-08 7.558908122096155 -0.1227355785934916 SS(ph)SLVDIR ddPTM_PC-9_AZD4547_30min_R2 1 SSSLVDIR 8 0 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 1 S(0.175)S(0.638)S(0.187)LVDIR 134.23 0.0039811 3258200.0 32289.0 40170.0 40035.0 32146.0 33082.0 43478.0 45839.0 54565.0 48088.0 35660.0 True False 42556.230347077886 53154.166932835775 39504.1097415957 24735.23635074912 28489.135336886528 40759.3137868683 49918.58219809049 46133.233028961775 50629.83350640224 34411.55425405926 1.2366843424998122 1.5446604515564886 1.1479896970052061 0.7188061361056164 0.8278944661014808 1.1844659350735443 1.4506343372212545 1.3406320646943695 1.4713033050644564 1.0 15.070605434774123 -7.009471974634583 24.208283515893232 1.3402458626878135 1.0925961158912108 0.15332419604377012 0.24147608714166235 582.0548791825314 1487606.1153074952 0.09797803628796593 0.08174123439058609 9.784260913547427e-08 7.009471974634583 -0.2476497467966028 SS(ph)SLVDIREEETEGGSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSLVDIREEETEGGSR 17 1 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 1 S(0.141)S(0.429)S(0.429)LVDIREEETEGGSR 65.16 0.010315000000000001 12755000.0 34740.0 29207.0 34237.0 24509.0 28894.0 29206.0 20609.0 30211.0 27341.0 19521.0 True False 34244.60122946425 29139.37298597272 31422.166018641856 26311.473619627246 27194.511727789668 27956.92746251129 21676.03317938853 31614.71335067782 24261.568666506224 22895.178839902535 1.4957123274259616 1.2727296515014586 1.3724359280338174 1.1492145924525679 1.187783328444419 1.2210836027097092 0.9467509876625539 1.3808458790275342 1.0596802425592893 1.0 14.48275621385258 -1.5228787452803376 0.3050290793075526 1.0927758296652699 4.380951816298207 0.49577177934455885 0.1191235901886081 48.71584604032867 0.6950907660941386 0.1145604417642909 87.90395770045298 0.029999999999999995 1.5228787452803376 3.2881759866329374 SS(ph)SPAPADIAQTVQEDLR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSPAPADIAQTVQEDLR 18 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 1 S(0.016)S(0.492)S(0.492)PAPADIAQTVQEDLR 217.65 1.2970999999999999e-27 6523300000.0 2092800.0 1901800.0 2183100.0 1622700.0 2163700.0 2018800.0 1863000.0 1782600.0 2305200.0 1566800.0 True False 2062956.2882274848 1897396.4989462402 2003613.9450097014 1742038.7711685111 2036435.4199978733 1932460.630052652 1959457.0242709916 1865426.1037012404 2045564.101167849 1837619.2923702274 1.1226244177958153 1.0325297012412784 1.090331361522314 0.9479867665742489 1.108192229181054 1.0516109827950788 1.0663019442637727 1.015131976164196 1.1131598964274079 1.0 20.80940647746346 -8.741080743181925 0.004933640053414579 2.435427624649408e-08 2.0855451778197946 0.07138343407853642 0.05166384393409208 26933.785744445042 70.97340696516673 15134.680649646698 14862.468959144247 1.8151781570218803e-09 8.741080743181925 2.0855451534655183 SS(ph)SPELVTHLK ddPTM_PC-9_AZD4547_30min_R2 1 SSSPELVTHLK 11 0 Q07960;H0YE29;E9PNR6 Q07960 ARHGAP1 Rho GTPase-activating protein 1 1 S(0.021)S(0.602)S(0.377)PELVTHLK 131.79 7.9783e-05 23970000.0 114130.0 120600.0 139010.0 173690.0 149660.0 136700.0 125500.0 173050.0 124400.0 124460.0 True False 150420.9659485276 159581.5915384614 137166.63657247936 133648.45398374952 128882.29231964305 128152.12739005679 136669.25687428526 146309.0987933996 130975.53003236665 120102.69328267581 1.2524362429949356 1.3287095166372942 1.1420779403309596 1.1127848204801882 1.0731007673267028 1.0670212622829005 1.137936653532141 1.2181999819857823 1.0905294998181292 1.0 16.873908978036503 -5.364796706844737 4.510226512367146 1.1094695554044993 1.2898603632339103 0.6392545964659826 0.05599462691676425 0.1372919042909147 4.5610420980570385 0.015116359713535749 0.03333143920589716 4.317211181005482e-06 5.364796706844737 0.18039080782941097 SS(ph)SPELVTHLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSPELVTHLK 11 0 Q07960;H0YE29;E9PNR6 Q07960 ARHGAP1 Rho GTPase-activating protein 1 1 S(0.017)S(0.492)S(0.492)PELVTHLK 113.07 0.0009119999999999999 25636000.0 34143.0 35578.0 40656.0 41934.0 33563.0 33325.0 35634.0 41209.0 36447.0 26745.0 True False 39922.73554501123 39109.94871318934 41625.3932287386 39584.57393186231 26986.571084011444 31577.37833469035 32258.489552181094 40127.30741454467 36979.968424050305 31593.656786696498 1.2636313616542785 1.2379050952296795 1.3175237519914529 1.252927896226645 0.8541768769031823 0.9994847556863693 1.0210432356714259 1.2701064547691592 1.1704871225803113 1.0 14.947347310072312 -6.040697350518033 24.562841277577075 1.061074231206619 1.272128165099891 0.5008199092668583 0.10531008774568769 391.91830955539297 236541.13785543165 0.03429885060723863 0.04428624064660794 9.105475905177353e-07 6.040697350518033 0.21105393389327198 SS(ph)SPELVTHLK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSPELVTHLK 11 0 Q07960;H0YE29;E9PNR6 Q07960 ARHGAP1 Rho GTPase-activating protein 1 1 S(0.209)S(0.396)S(0.396)PELVTHLK 131.32 9.326299999999999e-05 30385000.0 88655.0 101140.0 103100.0 84250.0 116300.0 100090.0 99824.0 103140.0 108690.0 88548.0 True False 87390.76344266432 100905.81654402312 94623.515977509 90446.02604976099 109459.46265459742 95809.38402118589 104992.39827741675 107932.26093108198 96448.18764355966 103853.40381720648 0.8414819373323745 0.9716178077478189 0.9111258032915021 0.8709009307865926 1.053980501662307 0.9225444761523758 1.0109673291230303 1.0392751413430295 0.9286954890117919 1.0 16.664188976028413 -6.2498330043865185 24.998618234050504 0.9919587892985042 0.9048659312620214 0.45611178729956847 0.04999826356499956 728.8136678209723 1569768.4074204233 0.014278445885935579 0.01828182097814956 5.62557599160535e-07 6.2498330043865185 -0.08709285803648281 SS(ph)SPSASLTENEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSPSASLTENEVK 14 0 O96028-5 O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 S(0.006)S(0.586)S(0.403)PS(0.005)ASLTENEVK 111.88 0.0024421 0.0 7712.1 9621.4 7595.2 12261.0 14735.0 12161.0 8060.0 13755.0 9734.4 9880.3 True False 9017.606209081834 10576.549006382593 7776.298372956402 11574.05592069833 11847.78252608255 11523.25575178302 7296.498450653297 13393.945824627193 9876.747184324498 11671.52017758823 0.7726162549414541 0.9061843569179435 0.6662626851203606 0.9916493948168764 1.0151019186714667 0.9872969053260165 0.6251540793001503 1.1475750905478774 0.8462262870684083 1.0 13.510704859175354 -5.7819355635915155 24.99998983753138 0.9422558036936333 0.7941373461845561 0.22147553562628697 0.13943107289382398 378.82180918419266 462062.2884824095 0.03849427536322019 0.057169835927085556 1.652206918502947e-06 5.7819355635915155 -0.14811845750907715 SS(ph)SPTQYGLTK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSPTQYGLTK 11 0 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 S(0.123)S(0.437)S(0.437)PT(0.003)QYGLTK;S(0.001)S(0.499)S(0.499)PTQYGLTK 211.77 9.9656e-07 489930000.0 430550.0 400360.0 439130.0 363800.0 380320.0 355980.0 351690.0 307180.0 379000.0 291372.0 True False 424410.27804679907 399432.9910180449 403026.4264908197 390555.0656012235 357950.3253378889 340755.5652299107 369898.7873676136 321452.70421572257 336313.0289530687 341735.2619712148 1.2419270858930216 1.1688375051319408 1.1793527661326553 1.142858548890752 1.0474491958282022 0.997133170467534 1.0824132845815926 0.940648332166551 0.9841332352217056 1.0 18.382519594449484 -6.14432938084995 0.7857705100387318 0.984918293457753 1.2284089097307578 0.8595872490235145 0.035716834146492765 0.25818864961871335 0.3334426183891019 0.019273954239424584 0.0387504944618422 7.172501027779935e-07 6.14432938084995 0.24349061627300483 SS(ph)SPVGLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSPVGLAK 9 0 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 S(0.016)S(0.492)S(0.492)PVGLAK 97.59700000000001 0.004732500000000001 15575000.0 83075.0 87856.0 97462.0 116060.0 115580.0 104940.0 102600.0 101280.0 93972.0 74739.0 True False 97137.95669395785 96577.7630599234 99785.8637066931 109557.53447159685 92932.92869797238 99436.76166368804 92880.98524032623 98621.50731503051 95346.16272244244 88288.5890664017 1.1002322918639071 1.0938872631353007 1.130223789527821 1.2409025405219558 1.0526040758005282 1.1262696880216514 1.0520157386417242 1.1170357161428577 1.0799375517342649 1.0 16.429939367127346 SS(ph)SPVTELASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSPVTELASR 11 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.011)S(0.495)S(0.495)PVTELASR 188.27 0.00076735 242900000.0 190770.0 250620.0 280300.0 236530.0 291300.0 206270.0 262310.0 196400.0 186560.0 210110.0 True False 223063.5931207511 275499.89731012157 286983.4150436702 223277.9909406064 234221.85611454732 195452.83808241814 237462.0978400574 191244.7081030013 189288.08706315505 248201.2797701549 0.8987205598912205 1.109985804929154 1.1562527611035254 0.8995843661538387 0.9436770685930663 0.787477156698853 0.9567319639123438 0.7705226511325894 0.7626394482673255 1.0 17.921151028717716 -5.895332500729636 6.113416346052978 0.8643524753258766 1.059586346557106 0.4167869639009796 0.09810438614711822 0.1920506547754698 9.789761427008523 0.027795496771783047 0.04165930178848927 1.2725284459081083e-06 5.895332500729636 0.19523387123122948 SS(ph)SQGPLSSIR ddPTM_PC-9_AZD4547_30min_R2 1 SSSQGPLSSIR 11 0 A0A0U1RQE4 A0A0U1RQE4 1 S(0.189)S(0.59)S(0.221)QGPLSSIR 83.243 0.01305 15306000.0 47706.0 40930.0 59875.0 73888.0 63164.0 74742.0 55303.0 62642.0 54023.0 51319.0 True False 62875.515653556875 54159.82207022575 59081.01837836997 56854.26315822036 54394.76889000363 70068.370924562 60224.85986389312 52962.118269957384 56878.54548985963 49522.33743028789 1.2696394983792139 1.0936443003415581 1.1930175642766812 1.1480529011429146 1.0983885598407914 1.414884162590196 1.2161150500755558 1.069459177780363 1.14854323202993 1.0 15.595791790214317 -8.454124331715745 1.2466593402345771 1.0097311214930693 1.1965578146461582 0.2829271817685258 0.09400211889876162 0.6313355060803659 2.135704784941273 0.09180549765298558 0.028604336498191437 3.5145980867959566e-09 8.454124331715745 0.18682669315308886 SS(ph)SSERPEPQQK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSSERPEPQQK 12 1 P78362;C9J2M4 P78362 SRPK2 SRSF protein kinase 2;SRSF protein kinase 2 N-terminal;SRSF protein kinase 2 C-terminal 1 S(0.061)S(0.883)S(0.048)S(0.009)ERPEPQQK 66.78399999999999 0.018136000000000003 12019000.0 17715.0 14044.0 17213.0 14063.0 15733.0 16838.0 13497.0 13660.0 18328.0 15540.0 True False 17462.38085146688 14011.481980860788 15797.81358410149 15097.23993279277 14807.615872268116 16117.8779912951 14195.808618671796 14294.693468281723 16263.707637603822 18226.06829425159 0.9580991670581214 0.7687605332456666 0.8667702396947586 0.8283322375980762 0.8124415882353718 0.8843310433758551 0.7788738848931606 0.7842993473688562 0.8923322010558533 1.0 14.153715758033066 -8.565761577073692 6.013383909210638 0.9999890019264397 0.8330218608426463 0.4646974829859728 0.05413254866227722 0.2714438183475492 35.136599713914016 0.04907979989611801 0.012720500232230123 2.717930973750527e-09 8.565761577073692 -0.1669671410837934 SS(ph)SSGSLNAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSGSLNAR 10 0 H0Y7V5;Q7Z3E2 H0Y7V5 CCDC186 Coiled-coil domain-containing protein 186 1 S(0.201)S(0.647)S(0.142)S(0.004)GS(0.006)LNAR 72.289 0.03095 4369400.0 6663.2 11961.0 17488.0 16043.0 11022.0 18965.0 16894.0 17669.0 15351.0 15601.0 True False 7791.148155801154 13148.409032504842 17904.980243609338 15144.162722107769 8862.318222089034 17970.44201402558 15293.678018031871 17205.207471852984 15575.479333761232 18429.337802551952 0.4227579004342899 0.713449890244247 0.9715476722733898 0.8217420986233549 0.480880990789688 0.9750997136498942 0.829854994351133 0.9335770854159795 0.8451459027249726 1.0 14.16971661296312 -4.8384243377419 3.24242077444931 0.8436934292770432 0.3892698303623742 0.4642417261244074 0.1413582266870688 0.27145316787280216 4.634898871292197 0.03643516683301785 0.28963683594409934 1.4506934903514878e-05 4.8384243377419 -0.45442359891466894 SS(ph)STEPPPPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSTEPPPPVR 11 0 Q8N684-2;Q8N684;Q8N684-3;F5H669;F5H6M0;F5H047;F5H5B7;F5H1W4;F5H2K8;F5H6P5;F5H6A8;F5GXA3;C9JM38;C9J286;C9J323;J3QT54 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 1 S(0.001)S(0.497)S(0.497)T(0.005)EPPPPVR 178.53 0.002061 23841000.0 79105.0 134650.0 96491.0 93375.0 113320.0 75649.0 108230.0 80421.0 83692.0 74463.0 True False 92495.91410503224 148017.162129151 98791.71138415534 88143.50147583462 91115.75947442667 71681.83326754667 97977.67088265573 78310.0339630928 84915.83717029162 87962.55245121641 1.0515374045828196 1.6827292751792369 1.1231110129386561 1.0020571143012087 1.035847152399983 0.8149130655036534 1.1138566145746356 0.8902655934924485 0.9653634962148866 1.0 16.424601847717824 -5.493720639845477 7.237482124205767 0.9780238315083385 1.377511650996157 0.4857728499307643 0.160265203393637 0.15100615902090547 29.04660810547099 0.03923295781710544 0.07884813889383001 3.2083324224126524e-06 5.493720639845477 0.3994878194878184 SS(ph)SVGS(ph)SSSYPISPAVSR ddPTM_PC-9_AZD4547_30min_R2 1 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 S(0.34)S(0.455)S(0.205)VGS(0.961)S(0.037)S(0.001)S(0.001)YPISPAVSR 94.61 0.016959000000000002 0.0 9986.7 9054.2 15405.0 20814.0 16592.0 12329.0 10785.0 17038.0 10838.0 15530.0 True False 13162.262863735727 11980.793085468798 15200.719634551819 16015.653873094383 14288.487198767341 11558.065680994976 11744.844106686574 14405.168594290317 11410.874553784477 14986.299426964106 0.8782863927070295 0.7994497336622243 1.0143077487963383 1.0686863659135364 0.953436655153091 0.7712421426866143 0.7837054213366816 0.9612225262476614 0.7614204299997808 1.0 13.871356561536428 -6.73005844433035 24.978471761704732 0.8486061915319761 0.9458303116956441 0.1591095392793609 0.09961489861475363 361.6027608562221 287826.24994513864 0.03425238107755433 0.034249165821214046 1.8618365667893565e-07 6.73005844433035 0.09722412016366799 SS(ph)SVGSSSSYPIS(ph)PAVSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 S(0.196)S(0.539)S(0.266)VGSSSS(0.004)YPIS(0.996)PAVSR 249.49 1.0770999999999998e-52 39616000.0 54815.0 46465.0 67804.0 49818.0 64947.0 80040.0 80229.0 77132.0 96128.0 76721.0 True False 54033.32804816014 46357.41314730109 62229.41685100894 53481.78190797625 61126.945150714884 76616.87578235308 84382.8650564881 80715.83430420975 85301.05236728396 89982.12262569362 0.6004895913928061 0.515184703300877 0.6915753378020432 0.594360083396221 0.6793232185129695 0.8514677532231918 0.9377736665259916 0.897020785339443 0.9479777746755107 1.0 16.457350779200823 -6.7735773367190175 1.6059682292414994 0.9438687390096998 0.5947284217370358 0.9228554529109202 0.0460057650581597 0.09553235191892985 0.5111139028225588 0.019999033280188813 0.018008130412965603 1.684312467175112e-07 6.7735773367190175 -0.34914031727266404 SS(ph)SVGSSSSYPISPAVSR ddPTM_PC-9_AZD4547_30min_R2 2 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 S(0.13)S(0.435)S(0.435)VGSSSSYPISPAVSR;S(0.021)S(0.489)S(0.489)VGSSSSYPISPAVSR 190.18 1.1045999999999997e-42 7166800.0 15859.1 62738.0 20937.2 49342.0 32949.0 29917.0 21429.0 22555.0 23254.3 32245.0 True False 20901.96391022772 83016.83159154221 20659.55904787655 37966.96422630072 28374.60009113941 28046.285260631546 23336.139486526332 19069.64301233818 24483.474823405628 31116.11236461413 0.6717408545547565 2.6679692700284314 0.6639505220250784 1.2201705592719712 0.9118941260607986 0.9013428455325397 0.7499696367295762 0.6128542919784723 0.7868423451012064 1.0 14.92537420135652 -5.347939126496661 24.999999919845656 0.854902457691178 1.6702691590434442 0.3189990088158816 0.4757151818072491 71.18218042462625 20571.176868846112 0.11418353884635014 0.23769202580247623 4.488082933769069e-06 5.347939126496661 0.8153667013522662 SS(ph)SVLSLEGSEK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSVLSLEGSEK 12 0 A1L390-3;A1L390;G3V311;A1L390-2;A0A0U1RR71 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 S(0.022)S(0.717)S(0.26)VLSLEGSEK 154.23 0.00025662 6402900.0 120750.0 112710.0 115400.0 105540.0 115000.0 124800.0 123940.0 120010.0 137530.0 114710.0 True False 119028.08285716189 112449.02691988183 105912.2574568822 113301.76367111932 108235.9260986991 119462.59492300914 130357.00675692236 125586.10271804486 122039.92314489605 134537.47065853284 0.8847206824577887 0.8358193919468481 0.7872324114498646 0.842157676344968 0.8045039465132415 0.8879503556761151 0.968927140660903 0.9334656144739982 0.9071073103094335 1.0 17.03764851490994 -7.0034917985382075 3.9854590792334395 0.9459442799378367 0.829748746670284 0.7491007004916397 0.03300124925644343 0.1127774850412253 4.0998188147038395 0.012633540577981446 0.010355642245043737 9.919920723996427e-08 7.0034917985382075 -0.11619553326755272 SS(ph)SVSSQEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSVSSQEEK 10 0 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4;A0A2R8Y670 P49815 TSC2 Tuberin 1 S(0.029)S(0.831)S(0.14)VSSQEEK 93.839 0.0065373 3898800.0 45466.0 41217.0 32802.0 33984.0 63575.0 57828.0 54020.0 67157.0 53208.0 52412.0 True False 53162.49580556719 45308.75136633664 33584.12408227774 32079.98665761454 51117.93512695609 54795.397879624084 48902.834529068365 65394.199908723254 53986.06634035359 61913.880706836266 0.858652295715284 0.7318028017154131 0.5424328712538532 0.5181388453021393 0.8256296414208109 0.885026059650204 0.7898525172509292 1.0562122606781246 0.8719541680157141 1.0 15.917975268503342 -6.483278960962269 4.8314125310703435 0.9115108101919119 0.6586036361674128 0.5409001140578737 0.11175858082551579 0.173264860019917 9.602301120109509 0.03829206196534928 0.04209445235983001 3.286404669887576e-07 6.483278960962269 -0.25290717402449914 SS(ph)TDSLPGPISR ddPTM_PC-9_AZD4547_30min_R2 1 SSTDSLPGPISR 12 0 Q9HCD5 Q9HCD5 NCOA5 Nuclear receptor coactivator 5 1 S(0.013)S(0.986)T(0.001)DSLPGPISR 139.78 7.3452e-05 10788000.0 22336.0 23823.0 44431.0 57136.0 55921.0 53894.0 44142.0 62974.0 44335.0 53643.0 True False 29438.383382338638 31523.318865843845 43841.8159093003 43964.17794240038 48157.33441672301 50523.99966027604 48070.552485615095 53242.81529855841 46678.45758830364 51764.97489765846 0.568693087179885 0.6089700406146584 0.8469397695251938 0.8493035692438646 0.930307307439675 0.9760267393187018 0.9286308470283741 1.0285490411967109 0.9017382444517537 1.0 15.659688654439428 -5.203302037233352 0.890841057784499 0.9678289253784128 0.4456866869668405 0.9201614772664123 0.04199313745446922 0.3062176027723177 0.29122376501001657 0.01482599523047542 0.1374231640894743 6.261782272673822e-06 5.203302037233352 -0.5221422384115724 SS(ph)TDSLPGPISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTDSLPGPISR 12 0 Q9HCD5 Q9HCD5 NCOA5 Nuclear receptor coactivator 5 1 S(0.023)S(0.927)T(0.051)DSLPGPISR 133.15 6.6247e-05 6555900.0 20406.0 21886.0 24718.0 28143.0 36552.0 33571.0 32351.0 29757.0 25919.0 28725.0 True False 23860.33276312858 24058.697440464937 25307.37086353701 26566.238950837065 29389.897990727477 31810.477661632078 29286.479079042787 28975.910280147684 26298.016341069495 33932.615113025124 0.7031681078411705 0.7090139489788378 0.7458125693891099 0.782911628306524 0.8661253455660153 0.9374602445368716 0.8630775724621677 0.8539250565755896 0.7750070618923482 1.0 15.050384999259636 -5.996037388250945 1.8542063151936377 0.8781460017289114 0.7116644541772438 0.6447664758492029 0.05529432654156217 0.22792882940994247 1.5769445826865827 0.01812038881083357 0.02952053116715463 1.0091660036097676e-06 5.996037388250945 -0.16648154755166766 SS(ph)TDSLPGPISR ddPTM_PC-9_Lapatinib_30min_R1 1 SSTDSLPGPISR 12 0 Q9HCD5 Q9HCD5 NCOA5 Nuclear receptor coactivator 5 1 S(0.19)S(0.787)T(0.023)DSLPGPISR 109.15 0.0013474000000000001 8217500.0 31837.0 35834.0 44816.0 32736.0 44799.0 41296.0 38968.0 33883.0 35629.0 32213.0 True False 31382.998541809233 35751.028574634416 41131.40147476277 35143.51464409472 42164.010898222754 39529.86634567778 40985.57236811165 35457.327875972886 31616.086829997093 37780.97412887556 0.8306561507587908 0.9462706930923287 1.0886802795094295 0.9301908024979944 1.1160117458696568 1.046290289150209 1.0848204238542078 0.9384969205670444 0.8368256128640496 1.0 15.205372279602361 -1.600059729823064 19.61631813617671 0.9890413863620001 0.0049287307333865105 0.0 0.09732601108258088 0.0 0.0 0.022917379976732117 0.0 0.02511540987987993 1.600059729823064 -0.9841126556286136 SS(ph)TGPEPPAPTPLLAER ddPTM_PC-9_Lapatinib_30min_R1 1 SSTGPEPPAPTPLLAER 17 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.243)S(0.744)T(0.013)GPEPPAPTPLLAER 101.3 0.0010747 2070100.0 10467.0 16189.0 14333.0 13370.0 13829.0 16205.0 17091.0 18918.0 14806.0 14059.0 True False 10317.738660587282 16151.515365149195 13154.59606697998 14353.27440101253 13015.605408860081 15511.949925700035 17975.888353094742 19796.999343554442 13138.392365908025 16489.07941756005 0.6257316372434596 0.979528023132003 0.7977762574768722 0.8704715428641218 0.7893470022952954 0.9407408098950982 1.0901693113292494 1.2006127717761867 0.796793564588954 1.0 14.009223235159608 -6.973613766951242 4.0497980263999604 1.0373480457036481 0.825118783293284 0.38066053513349984 0.1252082258851508 0.2213295007049133 8.164094120893107 0.04518261233097774 0.038014065341302444 1.0626401796246697e-07 6.973613766951242 -0.2122292624103641 SS(ph)TIQDQK ddPTM_PC-9_Lapatinib_30min_R1 1 SSTIQDQK 8 0 Q9Y6W5;Q9Y6W5-2 Q9Y6W5 WASF2 Wiskott-Aldrich syndrome protein family member 2 1 S(0.001)S(0.979)T(0.02)IQDQK 95.48299999999999 0.017759 0.0 21663.0 34702.0 33235.0 30442.0 41754.0 33417.0 40702.0 39456.0 37132.0 30199.0 True False 21354.08164749233 34621.64965108453 30502.54659081001 32680.806231535058 39298.11181152245 31987.832808831703 42809.35040358447 41289.26980120963 32949.803142705445 35418.856912361895 0.6029014911556709 0.9774920104494078 0.8611951161011073 0.9226951144244522 1.1095251297567037 0.9031300159680564 1.2086598534082884 1.1657425846173721 0.9302898516525896 1.0 15.112230031687893 -4.077062834054757 0.5858230270560022 1.065898510974198 5.004535167148596e-17 0.5447609608231673 0.11097956896007058 6.216204117419564 0.8805306137176805 0.05410251527538534 5.3828321147616505 8.374081165210296e-05 4.077062834054757 -1.065898510974198 SS(ph)TLSLPR ddPTM_PC-9_AZD4547_30min_R2 1 SSTLSLPR 8 0 A0A0B4J268 A0A0B4J268 TRAV4 1 S(0.124)S(0.438)T(0.438)LS(0.001)LPR 76.774 0.024481 2125300.0 20456.0 29420.0 19897.0 27573.0 25933.0 31064.0 17830.0 24348.0 20714.0 19894.0 True False 26960.58248876787 38929.43966054341 19633.152779531152 21216.470848603432 22332.650586164014 29121.56316931038 19416.83545871318 20585.576061379306 21808.899751530873 19197.517115262322 1.4043786145310317 2.027837215969658 1.022692292011163 1.1051674402069427 1.1633093202666929 1.5169442482829347 1.011424307744281 1.0723040869182743 1.1360271029107436 1.0 14.22863211356215 -5.273619904842884 24.93820599056107 1.141169836544742 1.7161079299763526 0.5838273811500568 0.19822004969957444 429.3445504691287 879033.459902658 0.050463933435875005 0.10630226923799366 5.325741650339342e-06 5.273619904842884 0.5749380934316106 SS(ph)TPEEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSTPEEVK 8 0 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 1 S(0.115)S(0.443)T(0.443)PEEVK;SS(0.532)T(0.468)PEEVK 120.31 0.0034216 16156900.0 221855.0 231368.0 209196.0 229783.0 246435.0 197149.0 221622.0 200054.0 172038.0 182452.0 True False 259410.66966401474 254336.68598215672 214184.02602024784 216909.0034765373 198147.8307984497 186810.15937902094 200628.35975566783 194802.79447473437 174553.73028608056 215529.10331076302 1.203599261905621 1.1800572733578285 0.9937591848624927 1.0064023843860412 0.9193553341738171 0.8667514340727649 0.9308643550861417 0.9038352198489678 0.8098847329884649 1.0 17.71752316680073 -5.298307579609554 0.9336259885294236 0.8966340989958336 1.2780492564489268 0.8195108060244488 0.05114738892235832 0.40931266907661673 0.47559172085391815 0.01828173098510668 0.1346573616725097 5.031441416909564e-06 5.298307579609554 0.3814151574530932 SS(ph)TPGLK ddPTM_PC-9_AZD4547_30min_R2 1 SSTPGLK 7 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 S(0.031)S(0.485)T(0.485)PGLK 87.696 0.017768 9110900.0 189990.0 170830.0 196280.0 230230.0 237950.0 241540.0 178380.0 229490.0 239500.0 268750.0 True False 250402.8679625057 226047.4567372748 193677.19895292618 177154.03051804195 204914.74981597692 226436.46561663764 194255.47443215078 194027.59365557486 252159.4810510596 259341.14430113364 0.9655346768723698 0.8716220380164594 0.7468047519989275 0.6830926538688353 0.7901359052308353 0.8731220270768576 0.7490345388720553 0.748155847690253 0.9723080451833935 1.0 17.984491581400675 -8.3179727298145 6.6783254390552935 0.990662390979407 0.7999631956698354 0.470245376898613 0.07752911060208112 0.24659134256282364 23.35355711079121 0.078875792305578 0.02073419384072343 4.8086954222484e-09 8.3179727298145 -0.19069919530957158 SS(ph)TPGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTPGLK 7 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 S(0.01)S(0.495)T(0.495)PGLK 82.279 0.035746 0.0 184000.0 169980.0 161420.0 186950.0 224470.0 180280.0 179460.0 142260.0 156760.0 153780.0 True False 215147.5658343462 186854.49104131552 165268.86498875925 176475.79760007747 180486.7148713779 170825.79943519787 162460.24962211418 138525.8257369294 159052.31843921615 181659.09667818955 1.184347878903536 1.0285996928209415 0.9097747815048001 0.9714668895040564 0.9935462532388976 0.9403646861561634 0.8943138691805438 0.7625592567066924 0.8755538332384121 1.0 17.470874085738892 -1.5228787452962975 0.5423549491719665 0.8910961692219944 12.917977380055712 0.6135864425878036 0.0655142418991697 91.43740350716496 0.8578878764557402 0.03557016301543617 1277.1719446172185 0.029999999998897527 1.5228787452962975 12.026881210833718 SS(ph)TPLPTISSSAENTR ddPTM_PC-9_AZD4547_30min_R2 4 SSTPLPTISSSAENTR 16 0 P42166;G5E972;P42167;H0YJH7;P42167-2;P42167-3 P42166;G5E972 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 S(0.008)S(0.945)T(0.047)PLPTISSSAENTR;S(0.035)S(0.964)T(0.001)PLPTISSSAENTR;S(0.002)S(0.499)T(0.499)PLPTISSSAENTR;S(0.002)S(0.972)T(0.026)PLPTISSSAENTR 155.06 8.8083e-06 135529400.0 49512.3 60102.4 87539.5 95589.3 99207.2 76047.1 81128.4 93754.2 82557.6 76401.5 True False 65256.18148018285 79529.32543350935 86378.66903270691 73552.66372496316 85433.99272092283 71291.86281524818 88348.67043346427 79266.64264718954 86921.42619131923 73726.70673980663 0.8851091329832809 1.0787044335803726 1.1716062313423423 0.9976393491240875 1.1587930140760674 0.9669747363984207 1.198326554110994 1.0751415077705049 1.1789679755814795 1.0 16.169899694958595 -4.766452282928294 5.100909145694522 1.0961275676199078 0.8731843288120639 0.3796390981050428 0.07938050296504996 0.15820157644356964 11.247690188685544 0.018161089014438744 0.12544571301865745 1.7121732873300997e-05 4.766452282928294 -0.22294323880784395 SS(ph)TPLPTISSSAENTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSTPLPTISSSAENTR 16 0 P42166;G5E972;P42167;H0YJH7;P42167-2;P42167-3 P42166;G5E972 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 S(0.105)S(0.446)T(0.446)PLPT(0.002)IS(0.001)S(0.001)SAENTR;S(0.031)S(0.962)T(0.004)PLPTIS(0.001)S(0.001)S(0.001)AENT(0.001)R;S(0.035)S(0.689)T(0.276)PLPTISSSAENTR 93.71600000000001 0.0027136 74779300.0 37107.0 45948.7 46330.0 35728.100000000006 68723.0 42942.0 41701.0 38961.8 29726.4 35721.9 True False 43388.482203342784 50510.18327162073 47434.682907503426 33726.370389063035 55257.22148218338 40690.04592492943 37750.779390904885 37939.094033439455 30161.092363176343 42197.99769559518 1.0282118719550495 1.196980568509136 1.124097954829143 0.7992410121531323 1.30947496326233 0.9642648501584435 0.8946106794741469 0.8990733235051035 0.7147517420317007 1.0 15.364886923904441 -6.993800867540379 24.993358673514237 0.8773754073076173 1.0884039339741667 0.3500737458633587 0.13835632612338053 181.7139040784743 732620.2250180758 0.04797519202316199 0.04220181416663983 1.0143763904091267e-07 6.993800867540379 0.21102852666654937 SS(ph)TPLPTISSSAENTR ddPTM_PC-9_Lapatinib_30min_R1 1 SSTPLPTISSSAENTR 16 0 P42166;G5E972;P42167;H0YJH7;P42167-2;P42167-3 P42166;G5E972 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 S(0.042)S(0.479)T(0.479)PLPTISSSAENTR 219.41 2.4972999999999997e-22 185350000.0 90711.0 95850.0 58549.0 41256.0 49299.0 44444.0 46772.0 48216.0 56931.0 25883.0 True False 89417.44450564007 95628.0652140063 53735.327225675814 44290.103865981546 46399.32974556318 42543.23372402419 49193.62530284637 50456.29138116186 50518.83126999252 30356.842063070384 2.945545004973291 3.1501321848737183 1.7701224361227532 1.458982583694409 1.5284636540639631 1.4014380558964254 1.6205119491889195 1.662106067433898 1.6641662253614167 1.0 14.889734098599588 -5.326241301640081 4.0397333596916845 1.5165593606274157 3.0623156486885637 0.9098264932755467 0.1943898309648672 0.05275590849899316 1.7045613566212046 0.04933821986358279 0.11529749345748576 4.7180082760074e-06 5.326241301640081 1.545756288061148 SS(ph)TPLSEAK ddPTM_PC-9_AZD4547_30min_R2 1 SSTPLSEAK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.066)S(0.868)T(0.066)PLSEAK 153.1 6.6791e-05 38314000.0 274460.0 310840.0 313960.0 306790.0 307210.0 311020.0 234510.0 318060.0 304120.0 283320.0 True False 361732.57087735675 411312.95119249856 309796.6852621801 236064.30535825033 264559.1943306004 291571.87023303297 255380.9356939334 268911.1352916989 320195.16232671496 273401.05303589604 1.3230840439735367 1.5044307497180542 1.1331217704618919 0.8634359770635426 0.967659748903254 1.0664621331752926 0.9340890711946281 0.9835775404142001 1.1711555561736446 1.0 18.060659274098924 -5.43621875013296 4.393183400250679 0.9958982265745313 1.4081089894968561 0.779273159305921 0.08725074998780423 0.09253663542444344 3.1389083729736362 0.02303475826105115 0.049651246973156156 3.6625304989006344e-06 5.43621875013296 0.41221076292232484 SS(ph)TPLSEAK ddPTM_PC-9_Lapatinib_30min_R1 1 SSTPLSEAK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.031)S(0.484)T(0.484)PLSEAK 176.6 0.0048186999999999995 32730000.0 286430.0 304120.0 347310.0 312950.0 266900.0 260910.0 247630.0 236440.0 269250.0 190730.0 True False 282345.45567517163 303415.8288250777 318755.51245537004 335965.38697059697 251201.46674558928 249751.48751091605 260451.06973710458 247425.8655666568 238924.22967180426 223697.42636825048 1.2621756998239881 1.3563670970697483 1.4249404547490638 1.5018741718446553 1.1229519750131665 1.116470097871289 1.1643006983386133 1.1060738140068924 1.0680687460323635 1.0 17.77118913276893 -6.310475761527225 9.302748009166464 1.1056854523979687 1.3868422339768163 0.8088705121043159 0.06897814850581861 0.21603570129193378 39.807970950009825 0.02221261625125343 0.025238585960357596 4.89242569560988e-07 6.310475761527225 0.2811567815788476 SS(ph)TPPGESYFGVSSLQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTPPGESYFGVSSLQLK 18 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.093)S(0.438)T(0.438)PPGES(0.031)YFGVSSLQLK 87.963 0.00090068 34890000.0 44883.0 34667.0 42904.0 51190.0 58800.0 54168.0 57696.0 55192.0 48981.0 43240.0 True False 52480.805420342105 38108.51065377856 43926.9940743261 48321.990260219194 47278.562099331786 51327.33472268586 52230.61719713312 53743.26848075785 49697.25446205196 51079.06971234836 1.0274424674507114 0.7460690037697737 0.8599803074273052 0.9460233033284347 0.9255955984629493 1.004860405871438 1.0225444098976293 1.0521583259721234 0.9729475251198174 1.0 15.640444629460811 -6.42544500738507 1.354549924909407 1.017112857264177 0.8708423441501275 0.39109214021770866 0.06878531156402864 0.3923787596456806 1.4721869635394058 0.02759957845699589 0.033559858150894704 3.754524932000122e-07 6.42544500738507 -0.14627051311404948 SS(ph)TPTSYQAPK ddPTM_PC-9_AZD4547_30min_R2 2 SSTPTSYQAPK 11 0 O94929 O94929 ABLIM3 Actin-binding LIM protein 3 1 S(0.044)S(0.45)T(0.45)PT(0.044)S(0.011)YQAPK;S(0.002)S(0.364)T(0.364)PT(0.26)S(0.01)YQAPK 132.56 0.00059512 0.0 48878.0 37755.0 51130.0 66500.0 55679.0 58173.0 52928.0 67118.0 59335.0 60231.0 True False 64420.1872744425 49958.565410734736 50451.98279225148 51169.45241475816 47948.93193949897 54535.43311383898 57638.48946487781 56746.45531820501 62471.326965196655 58122.33102288956 1.1083551905217417 0.8595416689509615 0.8680309599486407 0.8803750901629662 0.82496574200742 0.9382870947203065 0.9916754619180501 0.9763279331631984 1.0748248713664699 1.0 15.826804943630417 -7.27614743314968 2.395425537987796 1.0154470348927773 0.9008155148063641 0.2877100273488786 0.0759845171477646 0.3853554349550056 4.34583975589395 0.03663121154047034 0.023892602437450117 5.2948366565437694e-08 7.27614743314968 -0.1146315200864132 SS(ph)TQTLEDSWR ddPTM_PC-9_AZD4547_30min_R2 2 SSTQTLEDSWR 11 0 H0YBE8;H3BLZ3;Q8IX03;Q8IX03-2;H0YAU4 H0YBE8 WWC1 Protein KIBRA 1 S(0.255)S(0.705)T(0.039)QTLEDSWR;S(0.072)S(0.888)T(0.039)QT(0.001)LEDSWR 140.33 0.00012005 9056100.0 26572.4 38226.0 45947.0 65623.0 49715.0 53143.0 41994.0 55005.0 39314.0 45025.0 True False 35021.8704597446 50581.80694982773 45337.71275876351 50494.6312152432 42812.93039336536 49819.959808996326 45731.38464684248 46505.24113915593 41392.05777887826 43448.688454543386 0.8060512688751229 1.1641733904752294 1.0434771306433437 1.1621669838911566 0.9853676121468392 1.1466389799341965 1.0525377467880828 1.0703485604130571 0.9526652990269936 1.0 15.407025007942766 -10.154165504922393 9.733185055954902 1.0000000000162914 1.0522056221665377 0.007324108337997792 0.10436424939092913 0.0 0.0 0.0938422716825644 0.022760094017360132 7.011880323338652e-11 10.154165504922393 0.05220562215024627 SS(ph)TQTLEDSWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTQTLEDSWR 11 0 H0YBE8;H3BLZ3;Q8IX03;Q8IX03-2;H0YAU4 H0YBE8 WWC1 Protein KIBRA 1 S(0.086)S(0.652)T(0.26)QT(0.003)LEDSWR 86.699 0.010776 3408400.0 15806.0 17079.0 22393.0 20327.0 32673.0 31310.0 37064.0 40934.0 33040.0 21219.0 True False 18481.64361726994 18774.4902488212 22926.934045925413 19188.144091023172 26270.960195092986 29668.04848189511 33553.029599877664 39859.52587315807 33523.147494461045 25065.836730488434 0.7373240245672743 0.7490071227498719 0.9146686102059621 0.7655098171003395 1.048078325793079 1.1836049520664456 1.3385960325460018 1.5901933097918717 1.3374038878058156 1.0 14.6134347735252 -6.664784658547175 1.5056700861294103 1.3636811229748222 0.7869587583317358 0.720068134413165 0.146142809732478 0.19012534162779623 0.8946306066772521 0.06132021812257208 0.06024700344352756 2.1637911563529269e-07 6.664784658547175 -0.5767223646430865 SS(ph)TSGSDFDTK ddPTM_PC-9_AZD4547_30min_R2 2 SSTSGSDFDTK 11 0 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 S(0.241)S(0.751)T(0.008)SGSDFDTK;S(0.064)S(0.927)T(0.008)S(0.001)GSDFDTK 89.189 0.0094184 12120000.0 38687.0 46307.0 71703.0 86880.0 87024.0 73922.0 49967.0 90587.0 61015.0 65919.0 True False 50988.66126041075 61274.83216725978 70752.17137009201 66851.15828261939 74942.21974358291 69299.64565419004 54413.96620109486 76588.86063217388 64240.1283354087 63611.195874182034 0.8015674058582758 0.9632711871736637 1.1122597272032781 1.050933838987177 1.1781293955204484 1.0894252922277914 0.8554149226925623 1.2040154186640453 1.0098871346872749 1.0 15.95699308862264 -4.880677368293104 2.745949056301074 1.0667745673292484 0.7792796071966318 0.42445889798529157 0.09330258067562938 0.33176779887120744 3.980242693794731 0.023769952693093142 0.19776759386071927 1.3162022585817052e-05 4.880677368293104 -0.28749496013261655 SS(ph)TSGSDFDTK ddPTM_PC-9_Lapatinib_30min_R1 1 SSTSGSDFDTK 11 0 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 S(0.052)S(0.946)T(0.003)SGSDFDTK 122.34 0.00067847 5529800.0 16063.0 23223.0 27114.0 20521.0 23469.0 30298.0 25838.0 28696.0 33040.0 24519.0 True False 15833.938674406572 23169.228570316867 24884.791583066733 22030.18279604923 22088.5995618293 29002.225168087614 27175.76521369505 30029.320919898404 29318.68727337573 28757.076480486143 0.5506101666889227 0.8056879003691125 0.8653449734347284 0.7660786662718785 0.7681100537746974 1.008524812588923 0.9450114037891114 1.0442410910676394 1.0195294814919966 1.0 14.811629394635043 -3.841328213925984 0.27879805250074186 1.054146546423126 5.55199036457315e-20 0.744577781411518 0.07517435641264864 7.979707977406126 0.3396465756239335 0.09568133325448373 3.1500430144994143 0.0001441025898281554 3.841328213925984 -1.054146546423126 SS(ph)TSSEPTPTVK ddPTM_PC-9_AZD4547_30min_R2 4 SSTSSEPTPTVK 12 0 Q69YQ0-2;Q69YQ0;F8WAN1;A0A494C1J1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 S(0.424)S(0.573)T(0.002)S(0.001)SEPTPTVK;S(0.203)S(0.695)T(0.101)SSEPTPTVK;S(0.211)S(0.789)TSSEPTPTVK;S(0.021)S(0.979)TSSEPTPTVK 207.34 6.0959e-08 41333000.0 191310.0 196139.0 218719.0 220663.0 215496.0 233803.0 206025.0 263038.0 212894.0 210756.0 True False 252142.6005047991 259537.0960428052 215818.6431515439 169792.5545593651 185578.10013172438 219183.26144972554 224360.8258766902 222391.5211119221 224147.14220828481 203377.4965891337 1.23977630137803 1.276134775948816 1.0611726802181265 0.8348640208822247 0.9124809934435966 1.0777163900907036 1.1031742923355348 1.0934912900476932 1.102123617251078 1.0 17.633800530449697 -5.318675385057571 4.942711962372972 1.0187107712202548 1.2587067512513517 0.5601425563320261 0.08366492819281783 0.1574622298178839 8.181420570581661 0.025344671123015118 0.05637775004390275 4.800921611388458e-06 5.318675385057571 0.2399959800310969 SS(ph)TSSEPTPTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTSSEPTPTVK 12 0 Q69YQ0-2;Q69YQ0;F8WAN1;A0A494C1J1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 S(0.129)S(0.78)T(0.089)S(0.001)SEPTPTVK 141.13 7.7502e-05 8140500.0 34685.0 53094.0 44254.0 34081.0 35429.0 23038.0 30663.0 25958.0 27901.0 25575.0 True False 40556.485440023294 58364.8214339781 45309.18319422962 32171.552062092804 28486.94177920454 21829.84672391886 27758.37865910448 25276.630004774437 28308.99934149387 30211.54504841138 1.3424167938129297 1.931871453130038 1.4997307526518615 1.0648760932464951 0.9429157540124706 0.722566379473093 0.9188003663706734 0.8366546617947156 0.9370258719350882 1.0 14.88281234635885 -5.797107159353888 2.570127011257298 0.8823390837176701 1.6567775270192489 0.8126263961234547 0.15080888598217862 0.1005085405647456 1.353243605594446 0.042508811774693366 0.07493410366900335 1.595485422957611e-06 5.797107159353888 0.7744384433015787 SS(ph)TSSEPTPTVK ddPTM_PC-9_Lapatinib_30min_R1 2 SSTSSEPTPTVK 12 0 Q69YQ0-2;Q69YQ0;F8WAN1;A0A494C1J1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 S(0.104)S(0.896)TSSEPTPTVK;S(0.117)S(0.881)T(0.001)SSEPTPTVK 278.38 2.6632999999999996e-64 24725000.0 102858.0 115530.0 130237.0 109933.0 133951.0 109357.0 122147.0 141886.0 133121.0 117651.0 True False 101391.22605815297 115262.49738314206 119529.41658935843 118017.83954573759 126072.2655377985 104680.05603361789 128471.17399013882 148478.54154030912 118127.5111537244 137986.81858989692 0.7347892146096381 0.8353152754808227 0.8662379335275877 0.8552834303433863 0.9136544115310825 0.7586235924804655 0.9310394666896479 1.0760342404994065 0.8560782280574546 1.0 17.074170932286187 -1.5228787452810104 0.14105126829789055 1.0376445193948547 0.08760230257790698 0.4382700364414498 0.07331247824899736 72.9316975833293 0.6866410000426533 0.31782841246076643 13.984677663397473 0.029999999999953522 1.5228787452810104 -0.9500422168169477 SS(ph)TSSIDSNVSSK ddPTM_PC-9_AZD4547_30min_R2 2 SSTSSIDSNVSSK 13 0 Q8IVL0-3;Q8IVL0-2;Q8IVL0;H0YHA8;A0A2R8YFX5 Q8IVL0-3 NAV3 Neuron navigator 3 1 S(0.043)S(0.945)T(0.01)S(0.001)S(0.001)IDSNVSSK;S(0.182)S(0.816)T(0.002)SSIDSNVSSK 111.66 0.0013929 6842300.0 29992.0 32260.0 46345.0 53600.0 49016.0 57633.0 47255.0 56884.0 45723.0 50373.0 True False 39528.83212764597 42687.41412131644 45730.43501871496 41243.34811174495 42210.97447774713 54029.199399203746 51460.603454934986 48093.884864280415 48139.824434645445 48609.456602347906 0.8131922241183143 0.8781709795796108 0.9407723972891752 0.8484634676980288 0.8683696018874706 1.1114956466432513 1.0586541601547006 0.9893935918213373 0.9903386665778984 1.0 15.56894938609973 -6.743295103896328 24.980736794761015 1.0311058655472873 0.8730173287135089 0.7584398567961732 0.045179352632300704 125.86712100878516 173291.4002979988 0.01578068855662951 0.015750399869014955 1.805946564992745e-07 6.743295103896328 -0.15808853683377844 SS(ph)TSSIDSNVSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSTSSIDSNVSSK 13 0 Q8IVL0-3;Q8IVL0-2;Q8IVL0;H0YHA8;A0A2R8YFX5 Q8IVL0-3 NAV3 Neuron navigator 3 1 S(0.002)S(0.982)T(0.015)SSIDSNVSSK;S(0.213)S(0.784)T(0.003)SSIDSNVSSK 162.94 1.2447e-12 3839700.0 25791.0 29162.0 34314.0 40673.0 45489.0 35374.0 38744.0 45088.0 40970.0 28547.0 True False 30156.90690453049 32057.010635056115 35132.17589656966 38394.22367364514 36575.75699551878 33518.925167631984 35073.88783773096 43904.48777468487 41569.10874237497 33722.345122072344 0.8942707511996797 0.9506162907417072 1.0418070205198906 1.1385395509909215 1.0846148707368155 0.9939677992825233 1.040078550609874 1.301940526845151 1.2326873647695002 1.0 15.041417247334207 -3.251703463773352 0.4229634945054397 1.1450633039058835 2.1206595911209456e-08 0.3984158335129473 0.09263139407093322 19.621587832408025 0.986790752100837 0.070201160583759 14.867732497303393 0.0005601399344402364 3.251703463773352 -1.1450632826992877 SS(ph)TVTEAPIAVVTSR ddPTM_PC-9_AZD4547_30min_R2 1 SSTVTEAPIAVVTSR 15 0 Q8TD19 Q8TD19 NEK9 Serine/threonine-protein kinase Nek9 1 S(0.038)S(0.839)T(0.122)VTEAPIAVVTSR 111.66 0.00039924 14394000.0 14929.0 10744.0 17986.0 25266.0 18117.0 16219.0 15891.0 17026.0 13709.0 15902.0 True False 19676.111457509553 14216.787889628775 17747.49388815637 19441.31405580872 15601.767272183448 15204.823366052196 17305.268215053904 14395.022918557737 14433.629752521809 15345.275820192097 1.2822259885103349 0.926460238070247 1.1565444698493663 1.2669250317564738 1.0167146850272868 0.9908471860795695 1.1277261104868999 0.9380752152800037 0.940591092766759 1.0 13.905506956982853 -6.47564820640327 20.71174032412689 1.0036156300728958 1.1414450728331091 0.3510022727332194 0.10288737193625482 77.43062952100784 33954.519111326554 0.03215399367117755 0.03645616114668623 3.344658592739944e-07 6.47564820640327 0.13782944276021336 SS(ph)VDLEESSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSVDLEESSTK 11 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 S(0.179)S(0.821)VDLEESSTK 90.79299999999999 0.0085439 5394200.0 24080.0 29301.0 27266.0 32293.0 35972.0 35521.0 39574.0 25092.0 24772.0 24820.0 True False 28156.26839832092 32209.809636437123 27916.12484688083 30483.727905318592 28923.54482716264 33658.21622885331 35825.26422905131 24433.361587171596 25134.243635980278 29319.669524988094 0.9603201146017131 1.0985734204468391 0.9521295873778156 1.0397023022151874 0.9864894555688 1.147973929247996 1.221884994253388 0.8333436898512081 0.8572485312141486 1.0 14.839581221856516 -7.789840325825192 24.999841016112015 0.8839719974740017 1.055618945462017 0.4046272353609859 0.08920932951829183 215.83218804083063 189982.5566949446 0.049967501052705345 0.024010504266077867 1.6224064871609917e-08 7.789840325825192 0.17164694798801539 SS(ph)VDLEESSTK ddPTM_PC-9_Lapatinib_30min_R1 2 SSVDLEESSTK 11 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 S(0.02)S(0.98)VDLEESSTK;S(0.132)S(0.868)VDLEESSTK 186.76 0.00095558 6044900.0 36433.0 51269.0 51058.0 42444.0 53449.0 57348.0 56820.0 63683.0 61073.0 59661.0 True False 35913.45873900607 51150.28978045799 46860.2083295796 45565.47334903333 50305.23490477707 54895.359724717426 59761.861577604745 66641.9446662214 54194.3156127989 69973.32435671441 0.5132449982785466 0.7309969942216955 0.6696867522070651 0.6511834869635005 0.7189201794719353 0.784518389391769 0.8540663478120172 0.9523907185899859 0.7744996555619355 1.0 16.094517413706292 -6.219683951567063 0.2357641792592208 1.0243773850039826 0.4223294857086183 0.7643640673688086 0.06645928120435997 2.6156473266021965 0.24249611499346319 0.13079032380616154 0.47264789751449415 6.029982453971361e-07 6.219683951567063 -0.6020478992953643 SS(ph)VGPSKPVSQPR ddPTM_PC-9_Lapatinib_30min_R1 2 SSVGPSKPVSQPR 13 1 Q9Y657 Q9Y657 SPIN1 Spindlin-1 1 S(0.24)S(0.76)VGPSKPVSQPR;S(0.426)S(0.574)VGPSKPVSQPR 72.66199999999999 0.026095999999999998 3788300.0 24181.2 23823.0 27619.0 25926.0 22893.0 25685.3 21621.8 20220.9 29389.0 17944.0 True False 23836.371653711005 23767.839307180766 25348.272432423102 27832.68452660065 21546.478749369722 24586.799594358723 22741.27100772009 21160.436834024727 26078.901340110144 21045.596491122928 1.1326061327729642 1.1293497581409053 1.204445426059321 1.3224944485817034 1.023799860386854 1.1682633754158254 1.0805714638362662 1.0054567397483953 1.2391619002630918 1.0 14.361230779824265 -6.286352344800212 24.999221144719368 1.0903025854821737 1.1928916479238285 0.28794422785276075 0.08527014211344906 1089.9157735187919 1093686.111753693 0.026222064517938678 0.02974234396398951 5.171870658191011e-07 6.286352344800212 0.10258906244165478 SS(ph)VTDENWLSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSVTDENWLSPR 12 0 H3BRS1;Q12968;I3L3K7;H3BR83;Q12968-5;Q12968-6;Q12968-4;Q12968-3;Q12968-2 H3BRS1 NFATC3 Nuclear factor of activated T-cells, cytoplasmic 3 1 S(0.037)S(0.959)VT(0.004)DENWLSPR 106.29 0.0016886 3865200.0 9542.0 9238.6 8622.1 7766.8 8169.4 7472.0 5753.8 5509.5 5407.5 5640.0 True False 11157.272136909382 10155.747152219652 8827.683563496335 7331.651376305342 6568.664714528593 7080.155166295759 5208.758410095405 5364.881462797782 5486.5744575150775 6662.487353784563 1.6746406476211317 1.524317662899694 1.3249831624043313 1.1004375673809972 0.9859177760085841 1.0626894717141855 0.781803871963317 0.8052370200373156 0.8235024197679686 1.0 12.701845174124953 -5.38804473749234 0.6746769753689206 0.8471896106641951 1.88938883740129 0.930894538946833 0.07660431696173173 0.38735171666202467 0.22552993508282354 0.0390624264362937 0.2762890511824635 4.092185031901802e-06 5.38804473749234 1.042199226737095 SS(ph)WECTGSGR ddPTM_PC-9_AZD4547_30min_R2 1 SSWECTGSGR 10 0 Q8NEV8-2;Q8NEV8;E9PPH6 Q8NEV8-2 EXPH5 Exophilin-5 1 S(0.214)S(0.786)WECTGSGR 92.11200000000001 0.0076408000000000005 5970000.0 20752.0 25343.0 24197.0 24326.0 16096.0 22154.0 20522.0 28926.0 24543.0 21166.0 True False 27350.704331585384 33534.62914062377 23876.131969961065 18718.016532953498 13861.348237184126 20768.70687782972 22348.418243618147 24456.151353353776 25840.29287447245 20424.98478242899 1.3390807691134432 1.641843531235951 1.1689669404552505 0.9164274408202279 0.6786466861463042 1.016828511700847 1.0941706190569027 1.1973644834434678 1.2651315606708353 1.0 14.318047383045382 -5.447284108152887 4.780657577245173 1.0213161700369127 1.4843412037610806 0.5545038746210006 0.16489055796756744 0.16929243080216463 7.042057809907045 0.048627731524742174 0.10332737670896922 3.5703919269603624e-06 5.447284108152887 0.4630250337241679 SS(ph)WVMT(ph)CAYAPSGNFVACGGLDNMCS(ph)IY(ph)NLK ddPTM_PC-9_Lapatinib_30min_R1 1 SSWVMTCAYAPSGNFVACGGLDNMCSIYNLK 31 0 F5H8J8;F5H100;F5H0S8;E9PCP0;P16520-2;P16520 F5H8J8 GNB3 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 4 S(0.208)S(0.738)WVMT(0.652)CAY(0.391)APS(0.05)GNFVACGGLDNMCS(0.978)IY(0.984)NLK 40.625 0.017 22059000.0 32967.0 21521.0 71798.0 27669.0 46729.0 45307.0 36752.0 39176.0 70886.0 30192.0 True False 32496.884534592624 21471.169446746313 65895.04558829474 29703.870561078224 43980.49209274879 43369.32522577548 38654.83873108293 40996.25997901937 62902.072217327834 35410.64697168882 0.9177150748071399 0.606347844023091 1.8608822832573073 0.8388400975793179 1.2420132320065107 1.2247538222176428 1.0916162803234823 1.1577382365195505 1.7763604338440555 1.0 15.11189558233844 -5.207477507669915 24.99994786448291 1.2547007079393544 0.7620310871992224 0.30190210684912644 0.3103110198860335 382.4566916841896 177186.50404915377 0.07456220846086051 0.1972728132124065 6.2018676260703494e-06 5.207477507669915 -0.492669620740132 SSAADVTT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 SSAADVTTR 9 0 Q9NRR6-2;Q9NRR6 Q9NRR6-2 INPP5E 72 kDa inositol polyphosphate 5-phosphatase 1 S(0.004)S(0.004)AADVT(0.143)T(0.849)R 44.425 0.037564 1365000.0 2704.8 2352.6 3066.6 4056.0 3537.5 3234.4 2186.8 4796.0 4265.7 3850.0 True False 3564.8701366650052 3113.031942399538 3025.9348803191538 3120.9518645753283 3046.3791866947618 3032.1524566964176 2381.4209636070655 4054.8884011161126 4491.176193400849 3715.2126718487953 0.9595332627057995 0.8379148698506147 0.8144715114823731 0.840046624577821 0.819974374489522 0.816145056694031 0.6409918284494877 1.0914283405203518 1.2088611312702895 1.0 11.85922908273139 -7.861354913470762 8.08041800872887 1.1181107378686566 0.8201817348069361 0.6897590724723794 0.08642960011062532 0.13180890689374847 9.45197129539685 0.04669361260043926 0.022350123034037744 1.3760844476396151e-08 7.861354913470762 -0.29792900306172043 SSADKIGEVSS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 SSADKIGEVSSPK 13 1 P35251-2;P35251;A0A1W2PP02 P35251-2 RFC1 Replication factor C subunit 1 1 SSADKIGEVS(0.237)S(0.763)PK 53.6 0.040477 15697000.0 138040.0 66352.0 109460.0 195240.0 175900.0 101890.0 108190.0 106240.0 87371.0 143630.0 True False 181933.84858963205 87798.98641592023 108008.48888010647 150230.43442793074 151479.32125501262 95518.80219292543 117818.70040819842 89823.04915233003 91989.25268856829 138601.5574175699 1.3126392803907203 0.633463202375173 0.7792732700304761 1.083901488749698 1.0929121149674057 0.6891611030397913 0.8500532216477322 0.6480666655261088 0.6636956640496395 1.0 17.080583943066202 -6.774584202562516 24.991076398123525 0.7531906002881319 0.9557336830535975 0.21325688655018749 0.19775756670451294 393.4456368612547 748018.3378866808 0.06988829089412169 0.06199979022659816 1.6804120898355952e-07 6.774584202562516 0.20254308276546562 SSADKIGEVSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 SSADKIGEVSSPK 13 1 P35251-2;P35251;A0A1W2PP02 P35251-2 RFC1 Replication factor C subunit 1 1 SSADKIGEVS(0.315)S(0.685)PK;SSADKIGEVS(0.206)S(0.794)PK 202.92 5.8112000000000004e-08 23100800.0 604782.0 168623.0 199202.0 181772.0 145293.0 162261.0 103171.0 106056.0 149516.0 118351.0 True False 596157.6977765651 168232.56380366627 182824.38050195645 195140.11925361634 136747.15139702844 155321.4752788652 108512.68956042004 110983.74893646315 132675.9336067204 138807.81265720518 4.29484253345894 1.211981952479342 1.3171043978155106 1.4058295100112803 0.9851545729254759 1.1189678182051723 0.7817477091754129 0.7995497285916078 0.9558246835455304 1.0 17.082729245268 -4.7597154270084685 5.234515985914504 1.0551588075300162 4.482066101797981 0.9637853622206619 0.1881180470137063 0.031899164967365286 2.501644547746276 0.05472131003849008 0.4004660019201422 1.738939902023804e-05 4.7597154270084685 3.426907294267965 up SSAPADSERGPKPEPPGSGS(ph)PAPPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSAPADSERGPKPEPPGSGSPAPPR 25 2 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 S(0.002)S(0.005)APADS(0.246)ERGPKPEPPGS(0.185)GS(0.561)PAPPR 42.941 0.021467 6066600.0 94961.0 14753.0 27612.0 21943.0 20829.0 22728.0 9381.9 9904.8 27108.0 12409.0 True False 93606.83872628532 14718.840334921611 25341.847945402315 23556.76141970216 19603.87917138958 21755.97642155571 9867.648876010735 10365.01316725013 24054.811580104993 14553.879116046845 6.431744965029709 1.0113345189663479 1.7412435367462171 1.6185898777824053 1.3469865329425952 1.494857573577615 0.6780081651998087 0.7121821670087842 1.6528110058013739 1.0 13.829116112449482 -4.759758702989109 24.99999159098376 1.261246853829601 6.431751378258533 0.9472359995042259 0.3668360177459156 9.284966428008913 138071.81686110407 0.0967587031682276 0.6006733404114606 1.7387666311595042e-05 4.759758702989109 5.1705045244289325 SSAS(ph)APDVDDPEAFPALA ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSASAPDVDDPEAFPALA 18 0 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 S(0.11)S(0.152)AS(0.738)APDVDDPEAFPALA 96.135 0.0065086 0.0 515.48 0.0 592.77 606.25 962.71 407.88 931.17 733.7 779.24 493.63 True False 602.7405828059162 0.0 606.9038848927435 572.2837779890191 774.0738863715599 386.4900547682971 842.9628365130069 714.4411524194087 790.6349108227549 583.1212114270697 1.033645442824541 0.0 1.0407851283740313 0.981414784395292 1.3274665218868862 0.6627953968994574 1.4456048245098614 1.2252017906722348 1.3558671770622748 1.0 9.187651992494732 -5.449132289728652 9.60849390402254 1.141629119918124 0.515342080525714 0.3816233703886266 0.3144959377973057 0.4478169536265838 56.01654552836458 0.07764940810661014 0.16172024089593426 3.5552300679445796e-06 5.449132289728652 -0.6262870393924101 SSASAPDVDDPEAFPALA ddPTM_PC-9_Lapatinib_30min_R1 2 SSASAPDVDDPEAFPALA 18 0 Q8NC51;Q8NC51-2;Q8NC51-3;Q8NC51-4 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 ; 115.7 0.0014402999999999998 0.0 16400.5 16145.1 18996.8 17628.4 18754.1 17217.1 17578.8 14753.0 16715.2 15437.6 False True 16166.625862516656 16107.717012901981 17434.95643376861 18924.85134261849 17651.020709979242 16480.76476802036 18488.944250271 15438.478238474383 14832.558157140742 18105.968590691016 0.8928893133520925 0.889635753658801 0.9629397260046392 1.0452272270232752 0.9748730437461556 0.9102393327078764 1.021151901245255 0.8526734242989854 0.8192082120791228 1.0 14.144177736347467 -10.209553581678275 7.397387433007659 1.0000007770773316 0.9342133591483683 0.08385361767921473 0.06819482495836977 0.0 0.0 0.0705951709235943 0.017121843904500705 6.172291356983673e-11 10.209553581678275 -0.06578741792896325 SSAT(ph)IFGLYSS(ph)T(ph)DNS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 SSATIFGLYSSTDNSK 16 0 P35443 P35443 THBS4 Thrombospondin-4 4 S(0.15)S(0.163)AT(0.686)IFGLY(0.104)S(0.627)S(0.641)T(0.641)DNS(0.988)K 48.527 0.045324 0.0 1917.7 2182.5 2812.0 2839.7 3644.5 3327.5 2399.9 2502.1 3891.4 2816.9 True False 1890.3532463368906 2177.4465553424006 2580.808214633901 3048.5410109615023 3430.137675362686 3185.1905817813563 2524.1550791991153 2618.35670036513 3453.1095537413544 3303.7974117166864 0.5721758966312175 0.6590738728773862 0.7811641856371838 0.9227384827380956 1.0382409233683465 0.9640998477949346 0.7640163014376656 0.7925294363023929 1.0451940974029288 1.0 11.689909508322422 -5.3836834843420425 1.9393293093640123 0.9225867826743618 0.5880039856731518 0.6686508953510091 0.08978056432613389 0.24375132181063638 1.7082940248015128 0.0280955331218737 0.09204494479727998 4.133486424820658e-06 5.3836834843420425 -0.33458279700120996 SSATIQNET(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 SSATIQNETPK 11 0 F5GX09;Q5HYJ3-3;Q5HYJ3-2;Q5HYJ3 F5GX09 FAM76B Protein FAM76B 1 SS(0.001)AT(0.002)IQNET(0.997)PK;SSATIQNET(1)PK 168.82 0.005475 12735700.0 60296.0 61668.0 60898.0 58322.0 66923.0 72398.0 73570.0 74180.0 73403.0 62436.0 True False 79468.87376528881 81600.97501653268 60090.452729953635 44876.763965917686 57631.89662506667 67870.94161510855 80117.58747602522 62717.185486820956 77282.93272480552 60250.134644039346 1.3189825090814267 1.354370002633772 0.9973496836973208 0.7448408909133852 0.9565438644338083 1.1264861400906951 1.3297495175631346 1.0409468104487578 1.282701411065664 1.0 15.878676844959614 -5.255948584875339 24.829928916451316 1.0583722188771232 1.3366762930049234 0.3332343368479791 0.15663348896402596 509.4356710398601 2303699.1446997398 0.04447521399687885 0.11080950914766376 5.546913777070784e-06 5.255948584875339 0.2783040741278002 SSATIQNET(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSATIQNETPK 11 0 F5GX09;Q5HYJ3-3;Q5HYJ3-2;Q5HYJ3 F5GX09 FAM76B Protein FAM76B 1 SSATIQNET(1)PK;S(0.063)S(0.009)AT(0.139)IQNET(0.789)PK 123.28 0.0014344000000000002 13412600.0 88121.0 88252.0 73975.0 94957.0 100312.0 69101.0 88919.0 79608.0 66318.0 66180.0 True False 103038.144830915 97013.07532285052 75738.8445517499 89636.86714474777 80656.58369571707 65477.22191464172 80495.94860218857 77518.37435164826 67287.7752886704 78177.9101194082 1.317995641908763 1.2409269469428597 0.9688010901809361 1.1465753818161328 1.0317055492085037 0.8375412161137644 1.0296508115814278 0.9915636556828832 0.8607006146096216 1.0 16.254473398038698 -3.6061785119964087 0.5094455932907497 0.946453083968094 2.466389976601861 0.6807103035833806 0.08213293204101198 7.66919003072016 0.606139973379036 0.046186516821661 9.037663114417679 0.0002476403949650316 3.6061785119964087 1.519936892633767 SSATIQNET(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 SSATIQNETPK 11 0 F5GX09;Q5HYJ3-3;Q5HYJ3-2;Q5HYJ3 F5GX09 FAM76B Protein FAM76B 1 SSATIQNET(1)PK;SSATIQNET(1)PK 170.0 0.00023582 18422500.0 82542.0 90252.0 72018.0 94845.0 88634.0 72043.0 72524.0 77512.0 75920.0 74777.0 True False 81364.935943651 90043.02703906655 66096.95803751925 101820.21769364503 83420.7223811486 68961.8888304356 76278.93785734258 81113.49049146782 67369.09012695779 87702.10481591048 0.9277421119417669 1.0266917450621025 0.7536530414664376 1.160978039322647 0.951182671798486 0.7863196553285556 0.8697503670801802 0.9248750718323993 0.7681581903691782 1.0 16.420323846746676 -6.583268003961366 11.55505727269409 0.8654194415321342 0.968705928089803 0.1507328111895485 0.11208889819279953 1.1688690628405387 219.6690493823468 0.03567483702874975 0.03567229228188954 2.61054988186813e-07 6.583268003961366 0.10328648655766881 SSATSGDIWPGLS(ph)AYDNSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSATSGDIWPGLSAYDNSPR 20 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SSATSGDIWPGLS(0.786)AY(0.023)DNS(0.191)PR 130.77 3.7046e-05 9946800.0 10658.0 11900.0 8060.8 7905.0 11943.0 9329.0 8970.2 5301.4 7362.4 8256.3 True False 12462.188894904666 13081.353355639802 8253.000042754233 7462.10847835579 9602.854883542846 8839.7708172341 8120.4777173759585 5162.2438672976095 7470.0611717076235 9753.101833165163 1.2777667154594168 1.3412505661693193 0.8461923379790957 0.7651010525678189 0.9845949573589599 0.9063548159801527 0.8326046273568569 0.5292925220716487 0.7659164540152631 1.0 13.251645404821273 -5.276814070199947 7.420821262120316 0.8175423592332537 1.3105033486242144 0.6967095183506746 0.12671786671428395 0.08288686327804477 27.750474450837345 0.035436905902481254 0.07894060994121285 5.286715377614168e-06 5.276814070199947 0.49296098939096067 SSATSGDIWPGLSAY(ph)DNSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSATSGDIWPGLSAYDNSPR 20 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SSATSGDIWPGLS(0.036)AY(0.959)DNS(0.005)PR 139.39 1.9582e-05 8892100.0 40232.0 67100.0 60633.0 41738.0 49877.0 47102.0 50551.0 32195.0 37018.0 41484.0 True False 47042.482981779336 73761.24455154872 62078.72067193299 39399.555176421745 40103.959895040316 44631.888201667934 45762.44332245346 31349.915363422202 37559.31821882443 49004.72081283671 0.9599581877315099 1.505186507097232 1.2667906202145236 0.8039950952256235 0.8183693168706951 0.9107671151138704 0.9338374459316592 0.6397325572602821 0.7664428568479024 1.0 15.580633115822353 -5.759098410434899 24.831081376713104 0.8300891195100454 1.2700993726803453 0.5887736068592999 0.15450293334665705 35.13411515248461 372662.8476248017 0.04168269694855437 0.06800390234232602 1.7414122274550659e-06 5.759098410434899 0.44001025317029996 SSATSGDIWPGLSAY(ph)DNSPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSATSGDIWPGLSAYDNSPR 20 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SSATSGDIWPGLS(0.056)AY(0.906)DNS(0.039)PR 74.812 0.0042516 1891700.0 8283.9 10293.0 8541.2 8396.4 7549.5 10956.0 8936.8 8509.8 8608.3 6808.1 True False 8165.77006691879 10269.167190900038 7838.9755059854515 9013.899265569304 7105.453252888077 10487.437419683401 9399.503775901763 8905.196374552253 7638.742604582336 7984.871013776974 1.0226552254669732 1.2860780309640287 0.9817285078819937 1.1288722447760096 0.8898645000812708 1.313413504311909 1.177164134484327 1.1152586383909475 0.9566519723866004 1.0 12.963053387441073 -8.254868559126994 22.863833794948093 0.9783259715855831 1.117407524537723 0.1639294489111489 0.12275061909011574 258.36180843658474 899023.5156678542 0.08603113999410401 0.03062387015154634 5.560725292662035e-09 8.254868559126994 0.13908155295213998 SSATSGDIWPGLSAYDNS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 5 SSATSGDIWPGLSAYDNSPR 20 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SSATSGDIWPGLS(0.243)AY(0.002)DNS(0.755)PR;SSATSGDIWPGLS(0.015)AY(0.004)DNS(0.981)PR;SSATSGDIWPGLSAYDNS(1)PR;SSATSGDIWPGLS(0.012)AY(0.001)DNS(0.988)PR;SSATSGDIWPGLS(0.29)AY(0.005)DNS(0.705)PR 181.54 2.1878e-37 6908600.0 70989.7 81271.90000000001 90331.2 77035.1 87331.9 107279.0 87245.0 123300.0 106914.0 78812.2 True False 93562.94792251082 107541.45231637386 89133.34926664253 59275.84787543063 75207.3731433237 100570.82717101643 95009.63598403963 104246.8181521302 112565.25577074313 76053.0088665668 1.2302333506181826 1.4140328426065665 1.171989781798441 0.7794017456880463 0.988880969525785 1.3223780185668335 1.2492554522166477 1.370712608294417 1.4800894461419165 1.0 16.214717705618945 -6.785550530501031 24.754725818596928 1.3054547557402059 1.1177244520634069 0.15670436990864045 0.19130285214914478 398.5897137937813 409225.71198682877 0.07338269613266515 0.06475066617449544 1.6385114081157483e-07 6.785550530501031 -0.187730303676799 SSATSGDIWPGLSAYDNS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSATSGDIWPGLSAYDNSPR 20 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SSATSGDIWPGLS(0.001)AYDNS(0.999)PR;SSATSGDIWPGLS(0.003)AYDNS(0.997)PR;SSATSGDIWPGLS(0.004)AYDNS(0.996)PR;SSATSGDIWPGLS(0.096)AYDNS(0.904)PR 213.01 3.7585999999999994e-73 20022000.0 112889.5 168664.1 145385.0 112589.40000000001 126896.7 104940.59999999999 125133.7 77267.29999999999 95771.9 109263.4 True False 131999.46268074133 185407.9571857956 148851.52977568313 106281.38093775978 102032.20257058302 99437.33019863177 113280.13004646583 75239.11524647138 97172.38285486624 129071.98949140155 1.0226809333370879 1.4364693526177266 1.153244250454505 0.8234271537655347 0.7905061584053459 0.7704020879391189 0.8776507629024519 0.5829236501501639 0.7528541493608853 1.0 16.977816423134755 -5.73263512727348 3.6798445790784613 0.7798727255653698 1.2435230059491142 0.651599460320033 0.13587434763095196 0.11973501462927721 3.4143495929030827 0.036797817058899604 0.06388580125962214 1.8508229357732485e-06 5.73263512727348 0.46365028038374445 SSATSGDIWPGLSAYDNS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 5 SSATSGDIWPGLSAYDNSPR 20 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SSATSGDIWPGLSAYDNS(1)PR;SSATSGDIWPGLSAYDNS(1)PR;SSATSGDIWPGLS(0.14)AY(0.003)DNS(0.857)PR;SSATSGDIWPGLS(0.001)AY(0.008)DNS(0.99)PR;SSATSGDIWPGLSAYDNS(1)PR 204.05 5.8743e-37 39354600.0 273494.2 287383.1 220761.4 206247.7 271421.9 270216.3 259739.1 253157.5 240521.7 228931.9 True False 269594.12255530624 286717.68208871566 202611.24985564785 221415.84388015768 255457.39747798696 258659.77875396097 273187.1196848229 264920.1216468908 213431.61334021497 268502.47388241725 1.0040656931651477 1.0678400014082374 0.7545973298718115 0.8246324165233585 0.951415433102702 0.9633422553388964 1.0174473096454864 0.9866580289420528 0.7948962639118218 1.0 18.034575855166878 -6.483909155868745 24.94978638616629 0.9558830986950146 0.909493219101065 0.03591345823026115 0.09892810420008358 2093.944908753319 1340623.2369471644 0.03288808687848027 0.03728427935726068 3.281639300648585e-07 6.483909155868745 -0.04638987959394969 SSAWAEGGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 SSAWAEGGSPR 11 0 Q8N9B5-2;Q8N9B5 Q8N9B5-2 JMY Junction-mediating and -regulatory protein 1 SSAWAEGGS(1)PR;SSAWAEGGS(1)PR;SSAWAEGGS(1)PR 103.21 0.004520199999999999 6160100.0 41276.0 36771.2 56710.0 73802.0 59057.0 58210.0 58260.0 74164.0 59190.0 56029.0 True False 54400.90940586541 48656.77129999227 55957.98834634426 56788.08912953362 50857.95494802332 54570.11949798986 63445.02713542511 62703.65791917749 62318.66256122002 54067.44176390032 1.0061676238247272 0.8999273816664904 1.0349664515421222 1.0503195134978591 0.9406391959528607 1.0092972354098906 1.173442372444298 1.159730438014609 1.152609787482656 1.0 15.722472475531998 -7.175407952634524 5.502894341347737 1.1343566452447589 0.9870940252308726 0.5238049588267362 0.060969368656896165 0.16412460197467604 8.082290603635075 0.023222878107019743 0.017832827371260306 6.677164063847593e-08 7.175407952634524 -0.14726262001388624 SSAWAEGGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 SSAWAEGGSPR 11 0 Q8N9B5-2;Q8N9B5 Q8N9B5-2 JMY Junction-mediating and -regulatory protein 1 SS(0.001)AWAEGGS(0.999)PR;SSAWAEGGS(1)PR;SSAWAEGGS(1)PR;SSAWAEGGS(1)PR 117.09 0.0011964 14464200.0 79484.0 89938.0 86361.0 72851.0 82793.0 67333.0 70214.0 69759.0 83877.0 49731.0 True False 78350.54358441959 89729.75408677408 79260.73194310034 78208.70556381192 77923.27851730079 64453.324550889214 73849.33736025947 73000.25780774992 74429.88899603317 58326.93708760785 1.343299468421186 1.5383930404574266 1.358904408507679 1.3408676928524703 1.335974121189648 1.1050353021980128 1.2661274712460344 1.251570225573521 1.2760808763923002 1.0 15.831874695694271 -1.522878748879294 0.04739525225035459 0.40273070662058974 2.8747749653268464 0.6521484594093258 0.08211426700047882 338.1731964154373 1.2174148142158994 15.577156908191597 62.48094013795684 0.029999999751392892 1.522878748879294 2.4720442587062568 SSCS(ph)TPLSQANR ddPTM_PC-9_AZD4547_30min_R2 1 SSCSTPLSQANR 12 0 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 S(0.001)SCS(0.622)T(0.377)PLSQANR 132.86 7.4667e-05 4378200.0 34324.0 37649.0 52015.0 63965.0 61029.0 56036.0 41769.0 60692.0 49892.0 56531.0 True False 45238.31801644839 49818.302983677735 51325.24711400276 49218.85749939861 52556.17678722108 52532.060061662276 45486.360082725194 51313.44596341514 52529.189263463304 54551.86689669725 0.8292716746452407 0.9132281958015611 0.9408522573791176 0.9022396537336193 0.9634166487234006 0.962974560726587 0.8338185779940575 0.9406359283832655 0.962921935612869 1.0 15.735340949453414 -3.073708976405638 0.014315914402122133 1.7384629589686154 1.1039181732954382e-10 0.33724344794451755 0.043545743925688364 6401.222973134672 9.360933746351863 483.3712029560161 666.1204085697806 0.0008439000713321226 3.073708976405638 -1.7384629588582234 SSCST(ph)PLSQANR ddPTM_PC-9_AZD4547_30min_R2 1 SSCSTPLSQANR 12 0 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 S(0.098)S(0.002)CS(0.072)T(0.827)PLS(0.002)QANR 101.39 0.006690100000000001 5333000.0 22297.0 27225.0 29416.0 41089.0 36934.0 31663.0 24025.0 40056.0 26987.0 35130.0 True False 29386.98219358902 36024.948836107906 29025.924619927027 31616.565868721806 31806.351627246426 29683.107604618694 26163.17845740796 33866.265595310055 28413.477724947537 33900.1093927398 0.8668698337558364 1.0626794273361009 0.8562192022348857 0.9326390514684577 0.9382374333593807 0.875605068430126 0.7717726852825786 0.999001661114492 0.8381529804453284 1.0 15.049002308371499 -6.753840653686242 24.764781273930964 0.8890232198175607 0.9345262596445756 0.03679315273195438 0.08250853092880968 466.129854673172 1519146.0917542318 0.02639190683912304 0.02589554271521348 1.7626226489206161e-07 6.753840653686242 0.04550303982701487 SSCST(ph)PLSQANR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSCSTPLSQANR 12 0 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 S(0.001)S(0.001)CS(0.077)T(0.921)PLS(0.001)QANR;S(0.001)SCS(0.047)T(0.95)PLS(0.002)QANR 114.24 0.0011862 2239900.0 30367.0 28666.0 35382.0 30949.0 38724.0 31713.0 33569.0 29863.0 26779.0 20552.0 True False 35507.53332441076 31511.771033005913 36225.64106698222 29215.02786801178 31136.310182559944 30049.914452454166 30389.101301486444 29079.127892463963 27170.592214109332 24277.91491045752 1.4625445988821788 1.2979603540595848 1.4921232404261502 1.2033581951235706 1.2824952347595644 1.2377469219776531 1.251717926089138 1.1977605160786835 1.1191485065468212 1.0 14.567356901739615 -1.5228787483382908 0.0728942840700064 0.6974856568064153 2.6222288387963273 0.7632454366391632 0.06735732226385763 107.58814172355471 0.5792821600085626 2.5629470515037553 21.114307424408878 0.02999999978876407 1.5228787483382908 1.924743181989912 SSCST(ph)PLSQANR ddPTM_PC-9_Lapatinib_30min_R1 1 SSCSTPLSQANR 12 0 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 SSCS(0.002)T(0.998)PLSQANR 125.84 0.00068751 4289000.0 33929.0 30680.0 33729.0 29025.0 27372.0 26427.0 21897.0 21378.0 26105.0 22056.0 True False 33445.16623818345 30608.962344973566 30955.931817705175 31159.595324561615 25762.03277542254 25296.778814345853 23030.719517156136 22371.29992422595 23164.78000216323 25868.350212227357 1.2928990818430588 1.1832591600876594 1.196672055378044 1.2045451321373102 0.9958900573120213 0.9779046056979955 0.8903049219687021 0.8648135555877686 0.8954873353776456 1.0 14.658900426748184 -6.396678751173659 1.4868161544590264 0.9052014980323804 1.23052763474115 0.8987375561764971 0.04681703154450816 0.11158652043236696 0.4975602869945787 0.01790840743645841 0.02198222462717961 4.0116334954038944e-07 6.396678751173659 0.32532613670876964 SSDEENGPPS(ph)SPDLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSDEENGPPSSPDLDR 16 0 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 SSDEENGPPS(0.735)S(0.265)PDLDR;SSDEENGPPS(0.5)S(0.5)PDLDR 271.27 9.910399999999997e-70 104723000.0 49462.0 53445.0 66146.0 72260.0 75527.0 70145.0 75695.0 74573.0 69143.0 54845.0 True False 57834.939680969605 58750.66639429997 67723.17150010177 68211.50647008071 60728.026525106005 66466.47271678476 68524.62161565776 72615.53776662468 70154.08556929548 64787.96434721891 0.8926803035670965 0.9068145138723116 1.0453048213886174 1.052842254844032 0.9373349994397966 1.0259077189178254 1.0576751763400518 1.1208183263399873 1.0828258963859065 1.0 15.983438208256345 -2.9503658428865243 0.4377491760618222 1.0628523209822276 1.70715321577839e-09 0.5369783092903759 0.049507271594149874 19.095401361734247 0.7858411463952756 0.035244436455257946 14.820940220946168 0.001121073681472283 2.9503658428865243 -1.0628523192750743 SSDEENGPPSS(ph)PDLDR ddPTM_PC-9_AZD4547_30min_R2 2 SSDEENGPPSSPDLDR 16 0 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 SSDEENGPPS(0.066)S(0.934)PDLDR;SSDEENGPPS(0.026)S(0.974)PDLDR 216.71 4.4556e-22 196904000.0 77275.0 68807.0 95178.0 127555.0 110966.0 95588.0 83536.0 121119.0 83059.0 90192.0 True False 101846.84258014955 91047.51715577877 93915.87753179953 98149.16545510486 95560.28631258558 89610.86724916419 90970.54216932472 102402.84158773598 87449.32917169077 87034.40553230839 1.1701905925277167 1.0461094850815136 1.0790661113545108 1.1277053580686607 1.0979598898634664 1.0296027955967297 1.0452250648802925 1.1765788593767394 1.0047673519092213 1.0 16.40929820440298 -8.2971605542202 0.01096453780213948 2.159669558026498e-05 2.1226199548573383 0.2580950675099869 0.05236968515156362 1645.211087201071 14.952182358881071 1458.901425885738 1432.9574739911375 5.044747639344635e-09 8.2971605542202 2.122598358161758 SSDEENGPPSS(ph)PDLDR ddPTM_PC-9_Lapatinib_30min_R1 2 SSDEENGPPSSPDLDR 16 0 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 SSDEENGPPS(0.007)S(0.993)PDLDR;SSDEENGPPS(0.063)S(0.937)PDLDR 302.9 2.1994999999999995e-128 174134000.0 109630.0 81983.0 95737.0 89935.0 105661.0 97213.0 95254.0 96494.0 121200.0 83378.0 True False 108066.65609632015 81793.17340052043 87865.87341550716 96549.11991436509 99446.22771751854 93055.42660457116 100185.7860385985 100977.46350866611 107549.17970741952 97789.77620579826 1.1050915575151152 0.8364184536877042 0.8985179926232136 0.9873130265803839 1.0169389027768536 0.9515864563258261 1.0245016393918096 1.0325973473562244 1.0997998347095368 1.0 16.57739602071669 -7.100645037746498 0.9273062008085065 1.0515202705579223 0.9473603670017374 0.19055071527175793 0.07100935631290368 0.8581700019344116 1.4931236992908044 0.05037958292920351 0.03334262114025723 7.931493310010717e-08 7.100645037746498 -0.10415990355618487 SSDGRPDS(ph)GGTLR ddPTM_PC-9_AZD4547_30min_R2 1 SSDGRPDSGGTLR 13 1 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 SSDGRPDS(0.992)GGT(0.007)LR 89.26 0.0299 7507500.0 15125.0 12925.0 21735.0 28845.0 24968.0 18872.0 17140.0 25397.0 13842.0 22549.0 True False 19934.43538045629 17102.7534878492 21446.77969860328 22195.23090080751 21501.624179051538 17691.930856658048 18665.426795420284 21472.47721500124 14573.659860996926 21759.56637338144 0.9161228233317259 0.7859877901230176 0.9856253259182227 1.0200217467549821 0.9881458026366994 0.8130644955453089 0.8578032519183734 0.9868063014926898 0.6697587447709867 1.0 14.409362186266122 -6.761102678250836 24.999855460659514 0.8641817506106325 0.9377414027676625 0.11059271329711384 0.10442097889875229 22.508450491455005 1671292.404526717 0.035667387053142624 0.03358091218516945 1.7333941308869232e-07 6.761102678250836 0.07355965215702998 SSDGS(ph)LSHEEDLAK ddPTM_PC-9_AZD4547_30min_R2 2 SSDGSLSHEEDLAK 14 0 A0A2R8Y7R9;Q13136-2;Q13136;E9PJZ7;H0YEF9 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 S(0.001)S(0.065)DGS(0.927)LS(0.007)HEEDLAK;S(0.112)S(0.112)DGS(0.731)LS(0.045)HEEDLAK 160.87 0.00049531 19692300.0 39865.3 38535.1 67755.0 88475.0 68937.0 72961.0 51442.0 71572.0 52984.0 64859.0 True False 52541.636150248225 50990.81748004777 66856.52442966941 68078.45567512374 59366.28748923725 68398.73713610796 56020.23834364123 60512.1919609429 55784.62607102014 62588.30615154314 0.8394800783237492 0.814701988524586 1.068195139644645 1.0877184551102481 0.9485204367968592 1.0928357282987688 0.8950591857846599 0.9668290401473175 0.8912947082471051 1.0 15.933605512216673 -5.247989302800236 24.880417083086613 0.9943686043624521 0.8270910011452111 0.4832737269836407 0.0689536750641994 637.1074379853407 1178538.2209265707 0.01812233391231615 0.0473617610573357 5.649508900664729e-06 5.247989302800236 -0.16727760321724106 SSDGS(ph)LSHEEDLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSDGSLSHEEDLAK 14 0 A0A2R8Y7R9;Q13136-2;Q13136;E9PJZ7;H0YEF9 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 S(0.002)S(0.006)DGS(0.991)LS(0.002)HEEDLAK 190.34 1.918e-36 0.0 8493.5 11402.0 12081.0 13753.0 16299.0 14777.0 17167.0 12094.0 11090.0 8269.8 True False 9931.28179572835 12533.915206807145 12369.056857447633 12982.46399782759 13105.327953350492 14002.068106578221 15540.817481683036 11776.545314652221 11252.170269781267 9769.049276299214 1.0166067868879247 1.2830230304207595 1.2661474527983314 1.328938326611216 1.341515185632798 1.433309190132634 1.5908218949603177 1.2054955381608539 1.1518183552498058 1.0 13.254002450631749 -8.361350954042884 2.287145116848912 1.0158398806250841 1.324963683297234 0.3395060117443265 0.13909590687042758 0.33544315086138377 3.41646166868081 0.13925017125532174 0.039041283380634076 4.351600780289533e-09 8.361350954042884 0.3091238026721499 SSDGS(ph)LSHEEDLAK ddPTM_PC-9_Lapatinib_30min_R1 2 SSDGSLSHEEDLAK 14 0 A0A2R8Y7R9;Q13136-2;Q13136;E9PJZ7;H0YEF9 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 SS(0.007)DGS(0.993)LSHEEDLAK;S(0.239)S(0.239)DGS(0.519)LS(0.004)HEEDLAK 178.68 7.041899999999999e-05 8595700.0 23186.0 20742.8 25913.0 19945.4 28149.5 31234.0 24371.6 25157.0 32454.0 17810.6 True False 22855.36338820834 20694.771321033822 23782.533167072655 21412.25125190393 26493.801754046333 29898.19463001017 25633.44219684534 26325.88606014372 28798.688764229297 20889.13847886725 1.0941266635448008 0.9906953004294522 1.1385119204955505 1.0250423335345253 1.2683051424475502 1.4312794498565387 1.227118208957144 1.2602667212329803 1.378644159660478 1.0 14.35046537277324 -6.270980904643712 21.170870586624435 1.280775393996763 1.0624525601591068 0.41985001323320503 0.11307373854046224 72.23059276837876 160265.63583851763 0.03295314410636247 0.0380120460464987 5.358202163045068e-07 6.270980904643712 -0.21832283383765616 SSDGSLS(ph)HEEDLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSDGSLSHEEDLAK 14 0 A0A2R8Y7R9;Q13136-2;Q13136;E9PJZ7;H0YEF9 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 S(0.093)S(0.093)DGS(0.27)LS(0.543)HEEDLAK 108.66 0.0003766 6890000.0 41284.0 60283.0 72097.0 63622.0 106330.0 78939.0 90333.0 87500.0 73723.0 57259.0 True False 48272.56580383225 66267.4978435324 73816.06590939501 60057.46560530699 85495.39979629185 74799.29987583263 81776.00428571536 85203.21771391321 74801.05940478672 67639.6034380054 0.7136731049595246 0.9797144642379432 1.09131429159029 0.8879038692228914 1.263984344240753 1.1058506566258832 1.2089959155462313 1.2596646547758905 1.1058766699208267 1.0 16.045580580993086 -4.107240605616411 0.6483209965347575 1.160533316021452 7.289420291387589e-15 0.5773817231929191 0.10651165712857298 5.017335130214545 0.8448568785389327 0.04591184128584444 5.254766183669954 7.811948910652709e-05 4.107240605616411 -1.1605333160214446 SSDITSDLGNVLTST(ph)PNAK ddPTM_PC-9_Lapatinib_30min_R1 1 SSDITSDLGNVLTSTPNAK 19 0 Q5T8D3-4;Q5T8D3-2;B7Z2R7;Q5T8D3-3 Q5T8D3-4 ACBD5 Acyl-CoA-binding domain-containing protein 5 1 SSDITSDLGNVLTS(0.237)T(0.763)PNAK 130.47 2.5259000000000002e-06 0.0 21417.0 18540.0 8965.3 7280.9 6031.4 7766.9 6738.0 4511.9 10708.0 2878.4 True False 21111.58965260321 18497.071769094196 8228.207641058796 7816.361674370389 5676.644910188639 7434.727792528206 7086.860670712796 4721.539345500752 9501.95227976111 3375.927604773085 6.253567055986154 5.4791079473807285 2.4373175625642185 2.315322657784236 1.6815067071232999 2.2022770221780084 2.099233603437756 1.3985902241579948 2.814619681514109 1.0 11.721068251102112 -5.2355098427692575 2.5481513728666236 1.956255406158671 6.252423570875407 0.9153669719945995 0.4759378473998046 0.07079360366733932 0.8754686927324906 0.12097398404098145 0.41627924092371404 5.81420254958745e-06 5.2355098427692575 4.296168164716736 SSDPGPDIGVVEES(ph)PEKGDEISLR ddPTM_PC-9_AZD4547_30min_R2 1 SSDPGPDIGVVEESPEKGDEISLR 24 1 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 SSDPGPDIGVVEES(1)PEKGDEISLR 96.181 2.6699e-06 2922000.0 16851.0 20401.0 15567.0 16455.0 16790.0 19029.0 18534.0 18710.0 17129.0 15380.0 True False 22209.267477426052 26995.2242867011 15360.571408702892 12661.553977215726 14458.998316496129 17839.113621839013 20183.490094884448 15818.799413028033 18034.403970453433 14841.55088130766 1.496424979777399 1.8188951075659154 1.0349707743851027 0.8531152895323391 0.974224219027316 1.2019709910712002 1.3599313344203636 1.0658454456367614 1.2151293429291843 1.0 13.857354235110954 -5.267946491464858 24.9120428387969 1.0918088950192286 1.657660055234732 0.688847478284051 0.1530885890170692 259.00243541022843 991576.5985840978 0.0430544280296189 0.09314481209323493 5.395770986109333e-06 5.267946491464858 0.5658511602155034 SSDPGPDIGVVEES(ph)PEKGDEISLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSDPGPDIGVVEESPEKGDEISLR 24 1 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 SSDPGPDIGVVEES(0.999)PEKGDEISLR 81.017 5.2025e-05 2444800.0 6553.5 11035.0 7699.9 5941.9 6232.9 6078.6 9496.6 5755.0 5372.0 5751.4 True False 7662.878112474921 12130.481872225644 7883.494818033366 5608.994606899718 5011.607988247024 5759.827515236273 8597.01329856999 5603.937347926537 5450.555337174479 6794.083291942653 1.1278752089428463 1.7854479185752135 1.1603470960361473 0.8255704803548148 0.7376430009609198 0.8477711072613813 1.265367663179151 0.8248261181272898 0.8022502967601954 1.0 12.730063189681678 -5.518976856097304 5.3873064214229 0.9037104883926763 1.4646568817571946 0.5472640173803855 0.20268654610556425 0.11433701262987223 10.903078834759706 0.0540203853118836 0.10400217456931067 3.027074739053748e-06 5.518976856097304 0.5609463933645182 SSDQPLTVPVS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 SSDQPLTVPVSPK 13 0 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 SSDQPLTVPVS(1)PK;SSDQPLTVPVS(1)PK;SSDQPLTVPVS(1)PK;SSDQPLTVPVS(1)PK 203.2 1.1020000000000001e-09 597546000.0 924050.0 805474.0 711335.0 963769.0 971940.0 856459.0 913558.0 853505.0 848989.0 930300.0 True False 1217878.6785659953 1065827.7185974342 701902.2331219683 741586.9471326176 837002.9079056128 802904.483338413 994862.8922036508 721615.413843745 893864.8252946057 897730.4801612819 1.356619503826134 1.187246887736231 0.7818629851978157 0.8260685846373265 0.9323543384148447 0.8943714189075623 1.1081977432969843 0.8038218928626586 0.9956939694573123 1.0 19.77592285337027 -5.061671289806301 4.261725034787548 0.9149315923746453 1.3283798537432334 0.6983016717288489 0.0958827596939554 0.10561864469068531 3.779833724499536 0.024706423344166062 0.08059345545531836 8.676183130218465e-06 5.061671289806301 0.41344826136858814 SSDQPLTVPVS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 SSDQPLTVPVSPK 13 0 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 SSDQPLT(0.061)VPVS(0.939)PK;SSDQPLTVPVS(1)PK;SSDQPLTVPVS(1)PK;SSDQPLT(0.009)VPVS(0.991)PK;SSDQPLT(0.001)VPVS(0.999)PK;SSDQPLTVPVS(1)PK;SSDQPLT(0.025)VPVS(0.975)PK;SSDQPLT(0.025)VPVS(0.975)PK 184.99 4.819100000000001e-05 449106000.0 872008.0 829762.0 723001.0 980911.0 998985.0 886294.0 1085937.0 1040692.0 805599.0 809079.0 True False 1019621.7314569349 912135.287653984 740240.0858365615 925953.736826372 803241.0605238253 839815.1824085844 983069.185856961 1013374.9377043219 817379.3613314279 955758.6180341599 1.0668192912077854 0.9543573768972108 0.7745052692897659 0.9688154721857578 0.8404225139773907 0.8786896257717746 1.0285747544489574 1.060283337845982 0.8552152666042859 1.0 19.86628677827423 -7.258209864814126 24.974204615018152 0.9910419515368257 0.9085876941010358 0.13373739820537656 0.0888876760146777 537.127993722414 4153691.0883591645 0.03535227802413359 0.026245466736319736 5.518107224687476e-08 7.258209864814126 -0.08245425743578993 SSDQPLTVPVS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 5 SSDQPLTVPVSPK 13 0 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 SSDQPLTVPVS(1)PK;SSDQPLTVPVS(1)PK;SSDQPLTVPVS(1)PK;SSDQPLTVPVS(1)PK;S(0.001)S(0.001)DQPLT(0.021)VPVS(0.978)PK 201.57 2.1521e-07 581052000.0 853584.0 699172.0 614801.0 707020.0 729807.0 647486.0 664049.0 636655.0 635867.0 624396.0 True False 841411.7356318665 697553.1101909991 564254.4349804888 759016.6093495791 686881.1871157682 619794.5331435867 698430.2080032887 666236.3155233465 564248.9624836434 732322.0166446272 1.1489641394192538 0.9525223799593884 0.770500438544515 1.0364519871016058 0.9379496608103345 0.8463415260726123 0.9537200741326542 0.909758685906954 0.770492965743314 1.0 19.482118644340325 -4.794818033398812 4.064384647955655 0.9033481062281035 1.166610999156635 0.43575110002867634 0.08348758233643214 0.1947817874671298 6.053640813992232 0.020292229914309526 0.14505656035281106 1.603917280970254e-05 4.794818033398812 0.26326289292853144 SSDTS(ph)GNEASEIESVK ddPTM_PC-9_AZD4547_30min_R2 1 SSDTSGNEASEIESVK 16 0 D6R9S4;Q09GN1;Q71F23-3;Q71F23 D6R9S4 CENPU;MLF1IP Centromere protein U 1 SS(0.001)DT(0.239)S(0.759)GNEAS(0.001)EIESVK 125.61 0.00017494 0.0 10363.0 8536.4 12429.0 16176.0 12493.0 8891.0 9766.0 12828.0 8746.7 11540.0 True False 13658.218436209483 11295.624361599688 12264.183339035673 12446.873116708699 10758.562594877072 8335.044364484249 10635.155080751145 10845.727358114582 9209.032705258043 11135.988112502633 1.2264936257317915 1.0143351669815297 1.101310742714101 1.11771609227333 0.9661075861600628 0.7484782024081276 0.955025721409563 0.9739348900649266 0.8269614346048778 1.0 13.44294195579461 -6.3831825383753875 4.140883433197287 0.8988546979160829 1.1064191059162434 0.5891585378960318 0.08411049509307623 0.16920468575161557 4.892757859082283 0.026381307203317127 0.030065741110854978 4.138257031211872e-07 6.3831825383753875 0.20756440800016052 SSDTS(ph)GNEASEIESVK ddPTM_PC-9_Lapatinib_30min_R1 1 SSDTSGNEASEIESVK 16 0 D6R9S4;Q09GN1;Q71F23-3;Q71F23 D6R9S4 CENPU;MLF1IP Centromere protein U 1 SS(0.001)DT(0.077)S(0.92)GNEAS(0.002)EIESVK 105.31 0.0055708 0.0 7650.7 8663.9 8427.5 8208.8 7942.5 10032.0 8562.6 8575.9 8183.8 6361.7 True False 7541.599615033456 8643.839271858427 7734.6234810907545 8812.502535754053 7475.337765555801 9602.954745734205 9005.929530876425 8974.367621862171 7262.054264765503 7461.311368567587 1.0107606079548028 1.1584879446624488 1.036630573236034 1.181092987605189 1.001879883615004 1.2870331060286213 1.2070169821374672 1.2027869068256105 0.9732946269148479 1.0 12.865213499413764 -4.751598446620359 24.615730308344894 1.1269096706211372 1.0107603215947325 0.07939726286985038 0.10258337339835699 814.9461525740996 2038300.2982517683 0.024881111909208123 0.31986699935769114 1.771746377094397e-05 4.751598446620359 -0.11614934902640472 SSDTSST(ph)SPLNSSASQEELHQDEGLVAAPIVSNSEKPIAK ddPTM_PC-9_AZD4547_30min_R2 1 SSDTSSTSPLNSSASQEELHQDEGLVAAPIVSNSEKPIAK 40 1 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 S(0.002)S(0.002)DT(0.014)S(0.037)S(0.101)T(0.289)S(0.289)PLNS(0.089)S(0.089)AS(0.089)QEELHQDEGLVAAPIVSNSEKPIAK 61.357 2.3922e-05 7445000.0 9342.1 9621.2 15212.0 17565.0 16767.0 12803.0 11719.0 14360.0 12021.0 14921.0 True False 12312.69347224865 12731.064747179478 15010.278940655777 13515.660626544774 14439.191469487227 12002.426386063644 12761.968297288828 12140.991959972343 12656.405518642112 14398.620331598931 0.8551300880701364 0.8841864327264837 1.0424803623521144 0.9386774784861552 1.0028177100967972 0.8335816980827915 0.8863327182314586 0.843205229415485 0.8790012672857698 1.0 13.813642959542124 -6.76738262165211 24.999989299351867 0.8784937993563275 0.9464011383197082 0.1474769753220615 0.06539314505963471 242.3913040953827 1019602.3352442303 0.02280742941311911 0.02063626756675659 1.7085094227144283e-07 6.76738262165211 0.06790733896338064 SSDTSST(ph)SPLNSSASQEELHQDEGLVAAPIVSNSEKPIAK ddPTM_PC-9_Lapatinib_30min_R1 1 SSDTSSTSPLNSSASQEELHQDEGLVAAPIVSNSEKPIAK 40 1 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 S(0.001)S(0.001)DT(0.013)S(0.016)S(0.058)T(0.227)S(0.221)PLNS(0.023)S(0.221)AS(0.221)QEELHQDEGLVAAPIVSNSEKPIAK 79.17699999999999 6.587e-10 11326000.0 22409.0 22179.0 28680.0 24291.0 26619.0 27559.0 22531.0 21199.0 24194.0 19176.0 True False 22089.443550692708 22127.6458881737 26322.041108001544 26077.441172400544 25053.322754967583 26380.365813166765 23697.54493497032 22183.982930754333 21469.016945885363 22490.546049586123 0.9821657287462437 0.983864324120352 1.1703602504789308 1.1594845725357756 1.1139490655198485 1.1729535492381797 1.0536669444451487 0.9863692451861377 0.9545796219687802 1.0 14.457031068387126 -7.65221616407159 3.545269084599694 0.9765958046936477 1.0997865399164866 0.3874433567436364 0.06535296654585745 0.26639643185090767 6.442761524754235 0.03842896418413145 0.020269875495884368 2.2273262524884094e-08 7.65221616407159 0.12319073522283885 SSDTSSTSPLNSS(ph)ASQEELHQDEGLVAAPIVSNSEKPIAK ddPTM_PC-9_AZD4547_30min_R2 1 SSDTSSTSPLNSSASQEELHQDEGLVAAPIVSNSEKPIAK 40 1 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 S(0.001)S(0.001)DT(0.007)S(0.019)S(0.059)T(0.186)S(0.186)PLNS(0.066)S(0.238)AS(0.238)QEELHQDEGLVAAPIVSNSEKPIAK 66.959 6.932800000000001e-07 9614300.0 16293.0 14763.0 28239.0 36212.0 34391.0 31633.0 21427.0 28879.0 22715.0 26281.0 True False 21473.835084547067 19534.85104380022 27864.532408965162 27863.882869822897 29616.403281871248 29654.983509361173 23333.961490400852 24416.414123401213 23915.668526408397 25360.91018931384 0.846729668779607 0.7702740516005412 1.0987197305208019 1.0986941186978265 1.1677973330133284 1.1693185807604294 0.9200758693681637 0.9627578009281937 0.9430130207426698 1.0 14.63031890349859 -5.259926928480584 24.985540390205834 1.049991897672029 0.8085018428445323 0.5462021471452808 0.08614967257889025 103.89128272642958 1716230.6084064113 0.025085301932456963 0.059545198881730654 5.496333437522938e-06 5.259926928480584 -0.24149005482749675 SSDTSSTSPLNSS(ph)ASQEELHQDEGLVAAPIVSNSEKPIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSDTSSTSPLNSSASQEELHQDEGLVAAPIVSNSEKPIAK 40 1 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 S(0.001)S(0.001)DT(0.003)S(0.008)S(0.024)T(0.082)S(0.082)PLNS(0.124)S(0.513)AS(0.164)QEELHQDEGLVAAPIVSNSEKPIAK;S(0.001)S(0.001)DT(0.004)S(0.011)S(0.034)T(0.101)S(0.101)PLNS(0.122)S(0.475)AS(0.15)QEELHQDEGLVAAPIVSNSEKPIAK 88.51799999999999 1.1392e-14 15240000.0 63100.0 74181.0 82986.0 95614.0 116646.0 99174.0 94710.0 83435.0 87912.0 75922.0 True False 73781.58371819137 81545.19943484994 84964.70096615738 90257.05756477057 93790.0536503175 93973.1408541509 85738.38315897952 81244.91965668999 89197.54668683582 89686.05760177862 0.8226650350246654 0.9092293898893908 0.9473568494159386 1.0063666525016328 1.0457595768872048 1.0478010001443887 0.9559834098146286 0.9058812688303379 0.9945531008051232 1.0 16.45259610391161 -4.957323206989732 1.4907353025976842 0.991576871912766 0.7919663708601921 0.6438899150027124 0.03977422749813551 0.5928306340989474 1.5774504626676504 0.01328211690000937 0.15986472310577488 1.1032572574613218e-05 4.957323206989732 -0.19961050105257394 SSDTSSTSPLNSS(ph)ASQEELHQDEGLVAAPIVSNSEKPIAK ddPTM_PC-9_Lapatinib_30min_R1 1 SSDTSSTSPLNSSASQEELHQDEGLVAAPIVSNSEKPIAK 40 1 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 S(0.001)S(0.001)DT(0.002)S(0.005)S(0.015)T(0.041)S(0.041)PLNS(0.116)S(0.389)AS(0.389)QEELHQDEGLVAAPIVSNSEKPIAK 66.604 7.282300000000001e-07 6264400.0 26100.0 29080.0 45966.0 34597.0 43366.0 45949.0 33754.0 36856.0 39331.0 29251.0 True False 25727.80921384618 29012.66704666986 42186.85291389116 37141.37879220872 40815.29714083639 43983.86838235054 35501.61696040957 38568.46430944299 34901.12860620886 34306.99637549247 0.7499289338027005 0.8456778532613055 1.2296865762351536 1.082618203753361 1.189707682191414 1.2820670134145244 1.0348214857355011 1.1242157106179878 1.0173181069019734 1.0 15.066215201047758 -5.135260995431401 4.719095502470316 1.1277536705687037 0.7722652700178069 0.6812429372238122 0.08882265832365951 0.11649058601208682 3.8818905311124827 0.022713453928303578 0.06601103977501438 7.3238426414336665e-06 5.135260995431401 -0.3554884005508968 SSDTSSTSPLNSSAS(ph)QEELHQDEGLVAAPIVSNSEKPIAK ddPTM_PC-9_Lapatinib_30min_R1 1 SSDTSSTSPLNSSASQEELHQDEGLVAAPIVSNSEKPIAK 40 1 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 S(0.005)S(0.005)DT(0.026)S(0.025)S(0.152)T(0.144)S(0.144)PLNS(0.16)S(0.16)AS(0.179)QEELHQDEGLVAAPIVSNSEKPIAK 51.868 0.00052915 8045500.0 8453.8 9894.6 13096.0 10975.0 9937.4 12282.0 11596.0 9817.8 14061.0 11261.0 True False 8333.247261762952 9871.689661622417 12019.297432021896 11782.138111526745 9352.9016696801 11756.727490740377 12196.384140336242 10273.97082964101 12477.302111105817 13207.44884566069 0.6309505612433882 0.7474334958235149 0.9100392946795958 0.892082812450019 0.7081535411551488 0.89015885112461 0.9234473881262365 0.7778921538671357 0.9447170499702702 1.0 13.689064201686211 -4.986323382069145 3.032204084663509 0.8686217286706479 0.6319646228852299 0.5009961046308757 0.07964268534352387 0.23192607861109862 4.0351359152125275 0.020233384459595303 0.10545505334281335 1.0319926826410784e-05 4.986323382069145 -0.236657105785418 SSDVSPPLGQHET(ph)GGSPSK ddPTM_PC-9_AZD4547_30min_R2 1 SSDVSPPLGQHETGGSPSK 19 0 Q96PY6-4;Q96PY6-2;Q96PY6-6;Q96PY6;Q96PY6-3 Q96PY6-4 NEK1 Serine/threonine-protein kinase Nek1 1 SSDVSPPLGQHET(0.748)GGS(0.229)PS(0.023)K 64.749 0.023219 6771200.0 16255.0 18778.0 33672.0 44657.0 39233.0 38518.0 28188.0 44174.0 25080.0 44514.0 True False 21423.75187499617 24847.621276195918 33225.48727910603 34362.01859377228 33786.17516087508 36109.46337095986 30696.677392608355 37347.92331753611 26405.677598165214 42955.57840900708 0.4987420183475858 0.5784492304958878 0.7734848070894371 0.7999431009074045 0.7865375444179951 0.8406233767158002 0.7146144582276598 0.869454555166806 0.6147205689268143 1.0 15.390557878094015 -5.180571325858754 2.5828868617713256 0.7960463186543247 0.503489138912445 0.5589045421451969 0.09425805742152796 0.20868341370769306 2.596987624524004 0.023304280641653744 0.08824140072075906 6.598248597813687e-06 5.180571325858754 -0.2925571797418798 SSDVSPPLGQHET(ph)GGSPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSDVSPPLGQHETGGSPSK 19 0 Q96PY6-4;Q96PY6-2;Q96PY6-6;Q96PY6;Q96PY6-3 Q96PY6-4 NEK1 Serine/threonine-protein kinase Nek1 1 SSDVSPPLGQHET(0.428)GGS(0.428)PS(0.143)K 74.732 0.00893 4596300.0 35296.0 48508.0 53061.0 64354.0 65103.0 55541.0 64603.0 53537.0 52765.0 37655.0 True False 41270.91567222319 53323.553661796264 54326.17547496307 60748.454018483026 52346.53449579591 52628.3321856575 58483.33615478349 52131.71047714036 53536.588303427285 44481.55342318402 0.9278209166749238 1.1987790344121334 1.2213192052471795 1.3656999215054528 1.176814442557499 1.1831496010260139 1.3147772875283996 1.1719849345452273 1.2035683150292977 1.0 15.440919551531518 -4.760622760803225 4.827636160895876 1.21828185270325 0.9071219353074413 0.4443966437713188 0.0916594420158764 0.15690381937802023 9.03414424688722 0.021629052969248132 0.16765690063784314 1.735310678135882e-05 4.760622760803225 -0.3111599173958086 SSDYQFPS(ph)SPFTDTLK ddPTM_PC-9_AZD4547_30min_R2 2 SSDYQFPSSPFTDTLK 16 0 Q9UK61-3;Q9UK61 Q9UK61-3 FAM208A Protein FAM208A 1 SSDYQFPS(0.575)S(0.336)PFT(0.089)DTLK;S(0.018)S(0.018)DY(0.113)QFPS(0.46)S(0.316)PFT(0.071)DT(0.004)LK 149.09 3.1497000000000005e-10 3922500.0 35938.0 44650.0 54491.0 49249.0 50237.0 56369.0 55003.0 58479.0 51178.0 51088.0 True False 47365.53644316288 59082.2393216609 53768.413736213086 37895.403939465046 43262.45970374128 52844.23751902065 59898.160445070156 49442.414263734194 53883.16459804223 49299.424669976965 0.9607726004966582 1.198436690025748 1.0906499233237037 0.7686784215667146 0.877544920520905 1.071903736661707 1.2149870073747078 1.0029004312872702 1.0929775541753277 1.0 15.589283189831859 -6.969546560684642 24.70508175499696 1.087313354630724 0.984773010383579 0.1364912660978701 0.12112582351617719 396.3412916965447 321527.0150649807 0.04691270927513104 0.041372662453446896 1.0726386441479316e-07 6.969546560684642 -0.10254034424714509 SSDYQFPS(ph)SPFTDTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSDYQFPSSPFTDTLK 16 0 Q9UK61-3;Q9UK61 Q9UK61-3 FAM208A Protein FAM208A 1 SSDYQFPS(0.841)S(0.153)PFT(0.006)DTLK 216.71 4.458e-22 7828900.0 38379.0 52563.0 52769.0 42081.0 51127.0 32434.0 40380.0 23945.0 28529.0 36057.0 True False 44875.80668019761 57781.10726323485 54027.2130875469 39723.33799844274 41109.03136824044 30733.103943206184 36554.91407411667 23316.46912182465 28946.182653434586 42593.84867294505 1.053574825434876 1.3565599039172178 1.268427596256737 0.9326073890024965 0.965140100015246 0.7215385531180556 0.8582204992744829 0.5474140010417727 0.6795859861290429 1.0 15.378357473619692 -6.1836335259576725 1.2729154916615266 0.735693650740868 1.2439783888642728 0.6377911725229708 0.14430267676553252 0.26018941534255335 0.8573413262287048 0.0552371121474328 0.08550052974590838 6.551888138653702e-07 6.1836335259576725 0.5082847381234048 SSDYQFPSS(ph)PFTDTLK ddPTM_PC-9_AZD4547_30min_R2 2 SSDYQFPSSPFTDTLK 16 0 Q9UK61-3;Q9UK61 Q9UK61-3 FAM208A Protein FAM208A 1 SSDYQFPS(0.224)S(0.754)PFT(0.022)DTLK;SSDYQFPS(0.237)S(0.762)PFT(0.002)DTLK 183.75 8.115500000000001e-08 13851600.0 42268.0 49471.0 56746.0 52548.0 59301.0 56254.0 54291.0 69417.0 57065.0 54884.0 True False 55708.34477098359 65461.533291867556 55993.510962822256 40433.87045850697 51068.07975976992 52736.42848720017 59122.7938243969 58690.197693969465 60081.339399493554 52962.52786538943 1.0518445213297405 1.235997146100085 1.0572288223314497 0.7634429867334593 0.9642304062518603 0.9957309556907119 1.11631366944313 1.1081457033761226 1.1344122310815192 1.0 15.692684362189803 -9.506909204972752 13.097640102548347 0.999999607593466 1.0447979122629707 0.013646243833923544 0.11915485089480647 0.0 0.0 0.12753741665412352 0.030932367063727075 3.112366950725581e-10 9.506909204972752 0.04479830466950474 SSDYQFPSS(ph)PFTDTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSDYQFPSSPFTDTLK 16 0 Q9UK61-3;Q9UK61 Q9UK61-3 FAM208A Protein FAM208A 1 SSDYQFPS(0.297)S(0.685)PFT(0.015)DT(0.003)LK 162.81 6.3703e-05 7410200.0 36907.0 44642.0 43707.0 37361.0 47960.0 33366.0 43262.0 27088.0 28173.0 28671.0 True False 43154.62615352282 49073.76273130015 44749.14063972054 35267.78429599628 38562.58228374072 31616.228222513975 39163.91017024354 26376.96870210842 28584.976826920425 33868.8253404889 1.2741695562123054 1.44893607138581 1.3212486760272917 1.04130521036509 1.1385863517870698 0.9334905449088007 1.1563409647816916 0.7787978601837057 0.8439907950615627 1.0 15.047670330809067 -6.056636774198327 0.704096168613545 0.9054999566892936 1.4223876118985914 0.684348597624909 0.11447925396237658 0.5001778343884974 0.4956963603820248 0.06655198605547706 0.15932560008046948 8.777346148882972e-07 6.056636774198327 0.5168876552092978 SSDYQFPSS(ph)PFTDTLK ddPTM_PC-9_Lapatinib_30min_R1 2 SSDYQFPSSPFTDTLK 16 0 Q9UK61-3;Q9UK61 Q9UK61-3 FAM208A Protein FAM208A 1 S(0.003)S(0.003)DY(0.001)QFPS(0.029)S(0.659)PFT(0.303)DT(0.001)LK;SSDYQFPS(0.073)S(0.853)PFT(0.073)DTLK 219.03 2.7668e-22 16292100.0 55179.0 90577.0 95964.0 78704.0 93321.0 90465.0 80634.0 83791.0 81864.0 61746.0 True False 54392.13734141072 90367.27452153432 88074.21035175226 84492.15470884735 87832.04225614526 86596.02283421486 84808.8339748078 87684.2357540844 72643.61425386283 72418.71382862667 0.7510784777278086 1.247844234507969 1.2161802619164588 1.166717140389866 1.212836263068591 1.1957685832302642 1.1710900331025127 1.2107952643509026 1.0031055567455722 1.0 16.144074934028005 -4.75491997061219 24.970398048477048 1.1701999931400129 0.7510777627889851 0.6814154881868804 0.08316486870415613 116.28956370678854 445366.3126151922 0.01946770487901128 0.18119568866511165 1.7582475842592128e-05 4.75491997061219 -0.4191222303510278 SSEAPVQS(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 1 SSEAPVQSPQR 11 0 Q96NW4 Q96NW4 ANKRD27 Ankyrin repeat domain-containing protein 27 1 S(0.005)S(0.001)EAPVQS(0.995)PQR 73.46600000000001 0.024669 4675900.0 11772.0 11082.0 13876.0 23807.0 22338.0 16372.0 11690.0 18730.0 15511.0 11335.0 True False 15515.251127188858 14664.039779678526 13691.995173582658 18318.66396448342 19236.75428194701 15348.256251865501 12730.387353469268 15835.708872582323 16330.879793665888 10938.165100105483 1.4184509911117757 1.3406306858119295 1.2517634400536355 1.6747474367804855 1.7586820189577774 1.4031838166090114 1.1638503567062177 1.447748203437669 1.4930182205339357 1.0 13.417083122889913 -10.694117419105506 4.15571560014198 0.9998953391086343 1.4381421015324694 0.3801770953727076 0.16820310825033866 25400735.211239055 21788391.63800102 31746.369753066316 0.044700937994034705 2.0224722940101996e-11 10.694117419105506 0.4382467624238351 SSEAPVQS(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 2 SSEAPVQSPQR 11 0 Q96NW4 Q96NW4 ANKRD27 Ankyrin repeat domain-containing protein 27 1 SSEAPVQS(1)PQR;SSEAPVQS(1)PQR 90.434 0.008739499999999999 7235200.0 22510.0 22356.2 22673.5 20012.9 20546.5 23697.0 20735.4 19719.1 27727.0 16718.0 True False 22189.003272171558 22304.435592460824 20809.37235224104 21484.715427077303 19337.99526597322 22683.534550405027 21808.97755290859 20635.321374113755 24604.093281746038 19607.684024665257 1.131648349915225 1.1375354460222442 1.061286602031333 1.0957293783422282 0.9862457616946098 1.156869649769475 1.112266880957192 1.0524099301149383 1.254818939901092 1.0 14.259131520207033 SSEAS(ph)PTAQR ddPTM_PC-9_AZD4547_30min_R2 2 SSEASPTAQR 10 0 J3KNN7;Q7Z569 J3KNN7 BRAP BRCA1-associated protein 1 S(0.001)S(0.006)EAS(0.749)PT(0.244)AQR;S(0.001)S(0.003)EAS(0.733)PT(0.263)AQR 125.72 0.00037005 21909000.0 20866.4 23072.7 30282.0 31396.0 27300.5 29852.0 27791.0 33436.0 23735.0 29537.0 True False 27501.481151917556 30530.499063760006 29880.440894092677 24158.13726336463 23510.296815932255 27985.34972090695 30264.345161699275 28269.234482843705 24989.583644037142 28502.918620363092 0.9648654412629137 1.0711358885875064 1.0483291655874656 0.8475671416367004 0.8248382254838983 0.9818415473043388 1.0617981114424466 0.9918013961786903 0.8767377115613715 1.0 14.798822034389486 -5.7146122794654355 24.999969739290997 0.942251012593272 1.0324129217708646 0.22520069609288806 0.07416697411536897 201.51655654062174 107583.64563197576 0.02212859884108267 0.038327729797085014 1.9292464977794424e-06 5.7146122794654355 0.09016190917759259 SSEAS(ph)PTAQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSEASPTAQR 10 0 J3KNN7;Q7Z569 J3KNN7 BRAP BRCA1-associated protein 1 S(0.001)S(0.002)EAS(0.985)PT(0.012)AQR 118.77 0.00084579 9754700.0 17262.0 28197.0 26674.0 17746.0 28864.0 21629.0 24816.0 19486.0 15819.0 17831.0 True False 20184.115659959112 30996.211812518944 27310.009321708312 16751.749153308272 23208.306401957692 20494.737164321596 22465.248827718635 18974.51314712363 16050.322948392224 21063.619149881666 0.9582453763684056 1.4715520439275072 1.2965487615105185 0.7952930137080637 1.101819503895088 0.9729922013158282 1.066542680432239 0.9008192282678178 0.761992648755349 1.0 14.362465720993637 -5.746778001484868 24.999239483580748 0.951689642121118 1.2650591847937682 0.43735950949141433 0.1546984945745305 210.37476320045454 358708.8178608078 0.04114793753379505 0.07087835591147067 1.791521392852437e-06 5.746778001484868 0.31336954267265027 SSEAS(ph)PTAQR ddPTM_PC-9_Lapatinib_30min_R1 1 SSEASPTAQR 10 0 J3KNN7;Q7Z569 J3KNN7 BRAP BRCA1-associated protein 1 SSEAS(0.935)PT(0.064)AQR 113.67 0.0012735 8457700.0 11877.0 16556.0 21281.0 17075.0 23301.0 16501.0 19421.0 20535.0 22151.0 20057.0 True False 11707.631802024958 16517.66559919761 19531.35832703559 18330.752460530213 21930.480991528584 15795.290695709738 20426.524352317178 21489.13106670315 19656.1211196291 23523.825725727416 0.4976925071001787 0.7021674872013975 0.8302798428605358 0.7792419768049178 0.9322667684765139 0.6714592634664364 0.8683334331106356 0.9135049424890539 0.8355835206741774 1.0 14.521835087117376 -4.372240290470871 1.0030648424141735 0.8549461516981693 4.514085408311742e-15 0.645288537794239 0.08317879196952295 2.446637537261109 1.1358143460209216 0.02609417163938309 2.7397205599238337 4.2438469148579844e-05 4.372240290470871 -0.8549461516981648 SSEASPT(ph)AQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSEASPTAQR 10 0 J3KNN7;Q7Z569 J3KNN7 BRAP BRCA1-associated protein 1 SS(0.001)EAS(0.126)PT(0.873)AQR 90.05 0.021903 11963000.0 5356.1 7752.9 9766.9 4555.9 9926.4 8671.6 8313.0 7243.9 6834.5 6379.1 True False 6262.781942202931 8522.556674868889 9999.779937174515 4300.6476934270895 7981.393177258624 8216.846030520652 7525.532459091916 7053.755300546484 6934.441632896306 7535.580333072189 0.8310948414572406 1.1309754920221675 1.327008603874533 0.5707122083952031 1.0591610499100976 1.0904065337155946 0.9986666091347769 0.9360599965458442 0.9202266217589635 1.0 12.879502906160756 SSEASPT(ph)AQR ddPTM_PC-9_Lapatinib_30min_R1 1 SSEASPTAQR 10 0 J3KNN7;Q7Z569 J3KNN7 BRAP BRCA1-associated protein 1 S(0.007)S(0.007)EAS(0.291)PT(0.696)AQR 95.48299999999999 0.014424000000000001 10231000.0 4958.6 8681.5 10802.0 6863.9 11378.0 8206.4 9347.3 7543.5 11224.0 7165.2 True False 4887.889454704128 8661.398520139766 9913.901256925825 7368.6941032991745 10708.768410008674 7855.431402052745 9831.257457309845 7893.998548900667 9959.834926040226 8403.695272971141 0.581635732369435 1.030665467844542 1.1797073709719068 0.8768397548872521 1.274292803601691 0.9347591918662519 1.169873149604815 0.939348499973599 1.1851732603958294 1.0 13.036808133947682 -4.764744924786364 4.96506002479616 1.0693008546144804 0.5511559444313472 0.5783933911652517 0.12435327556280866 0.11081313300957846 7.109747449719486 0.02779154720587674 0.20042917457822404 1.718917666749268e-05 4.764744924786364 -0.5181449101831332 SSEGGVGVGPGGGDEPPT(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 SSEGGVGVGPGGGDEPPTSPR 21 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 SSEGGVGVGPGGGDEPPT(0.68)S(0.32)PR 210.43 5.1318999999999985e-79 0.0 12407.0 7584.8 11284.0 18933.0 16548.0 12225.0 9009.3 16165.0 9062.4 13210.0 True False 16352.167918368348 10036.438271151925 11134.366787165376 14568.289361934087 14250.595839272062 11460.5688174356 9811.110246673281 13667.070684746026 9541.419962743717 12747.521920811068 1.2827722925247522 0.7873246528618913 0.8734534332502599 1.1428330504104103 1.1179110675626405 0.8990428797557553 0.7696484310927973 1.072135491874208 0.7484921400422773 1.0 13.637929198395955 -6.850081463213921 10.413476178564336 0.8939149743795168 1.023063953469651 0.16610363649732218 0.15759578592947718 0.7967094218389646 87.48049838746374 0.05553639843108356 0.04899129529409728 1.4122726113540435e-07 6.850081463213921 0.12914897909013423 SSEGGVGVGPGGGDEPPT(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSEGGVGVGPGGGDEPPTSPR 21 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 SSEGGVGVGPGGGDEPPT(0.614)S(0.386)PR;SSEGGVGVGPGGGDEPPT(0.713)S(0.287)PR;SSEGGVGVGPGGGDEPPT(0.857)S(0.143)PR 295.52 2.1672999999999995e-131 46134000.0 80859.0 81753.0 93517.0 110445.0 126139.0 110951.0 119148.0 113602.0 102795.0 91840.0 True False 94546.83166195302 89868.8975532456 95746.79994519739 104257.12471752115 101422.96844638785 105132.53424192741 107861.43888318112 110620.0678712685 104298.18240596635 108489.86499496008 0.8714807753364355 0.828362147537196 0.8825414240274456 0.9609849244661188 0.9348612282916886 0.9690539687445584 0.9942075131920558 1.0196350403460026 0.9613633716920151 1.0 16.72720074840185 -5.844256435940878 0.8710975204113183 0.9929016592878814 0.8336844086404974 0.8416379086428616 0.023561808421910146 0.2727132488846791 0.3918752928883279 0.010585155878160162 0.030750530177130784 1.431342491239149e-06 5.844256435940878 -0.159217250647384 SSEGGVGVGPGGGDEPPT(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSEGGVGVGPGGGDEPPTSPR 21 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 SSEGGVGVGPGGGDEPPT(0.901)S(0.099)PR 193.19 6.1151e-53 0.0 15076.0 11738.0 15580.0 11723.0 13418.0 14262.0 13040.0 12201.0 15667.0 9511.3 True False 14861.0134754002 11710.821382180573 14299.072540539182 12585.148526781588 12628.779620802998 13652.047506345814 13715.147394789981 12767.903001940353 13902.417479176069 11155.315531989389 1.3321912260378665 1.0497974125965506 1.2818169508100996 1.128175038231053 1.1320862762320125 1.223815450777408 1.2294719369846532 1.144557763993914 1.2462594571448016 1.0 13.445443700840897 -11.754147270704394 2.43068295243199 0.3030550699075409 1.1910069229699103 0.3525436096955752 0.07956469555476274 5572153.926517695 1231327.1066787848 21398558.71712497 0.018678137567970182 1.7613786557637306e-12 11.754147270704394 0.8879518530623693 SSEGGVGVGPGGGDEPPTS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 5 SSEGGVGVGPGGGDEPPTSPR 21 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 SSEGGVGVGPGGGDEPPT(0.001)S(0.999)PR;SSEGGVGVGPGGGDEPPT(0.004)S(0.996)PR;SSEGGVGVGPGGGDEPPT(0.061)S(0.939)PR;SSEGGVGVGPGGGDEPPT(0.054)S(0.946)PR;SSEGGVGVGPGGGDEPPT(0.101)S(0.899)PR 278.46 3.981699999999999e-101 89659000.0 127460.0 119910.9 167402.0 239889.0 197170.0 179129.0 148774.0 205374.0 158776.8 161321.0 True False 167989.62866730266 158669.75343954636 165182.14010147634 184586.29729810395 169796.3489019378 167928.035312754 162014.59778657247 173638.16732502534 167169.41749873842 155673.20089229115 1.0791172000345335 1.0192489942397247 1.0610826985934743 1.1857294398784637 1.0907230527071794 1.0787215419880898 1.0407353151212513 1.1154017925356592 1.0738483987003093 1.0 17.248161080591018 -10.051668240191734 14.883030206487252 1.0000000005961316 1.083102004013495 0.2537730990632676 0.04255753356531228 0.0 0.0 0.0434869511675924 0.010547134882356514 8.878339740353552e-11 10.051668240191734 0.08310200341736351 SSEGGVGVGPGGGDEPPTS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSEGGVGVGPGGGDEPPTSPR 21 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 SSEGGVGVGPGGGDEPPT(0.125)S(0.875)PR 251.38 5.5160999999999994e-62 13889000.0 23176.0 15045.0 21895.0 25706.0 29590.0 24176.0 32679.0 23275.0 25767.0 19623.0 True False 27099.239053134774 16538.568171058894 22417.059837249893 24265.77615997647 23792.051913592302 22908.168000584345 29583.408544528433 22664.05591190096 26143.793628625226 23180.49456441747 1.1690535323923872 0.7134691680153336 0.9670656411127887 1.0468187420481068 1.0263824116209146 0.9882519088159943 1.2762199038643276 0.9777209821351589 1.127835886157342 1.0 14.500623726654014 -5.718776245083649 3.7396757296731415 1.0679249575969452 0.9203784546272159 0.1311694159562773 0.1316064185164783 0.36294879478023806 10.509580923673884 0.035467085098957185 0.062128874322028224 1.9108374966317054e-06 5.718776245083649 -0.14754650296972927 SSEGGVGVGPGGGDEPPTS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 SSEGGVGVGPGGGDEPPTSPR 21 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 SSEGGVGVGPGGGDEPPT(0.042)S(0.958)PR;SSEGGVGVGPGGGDEPPT(0.012)S(0.988)PR;SSEGGVGVGPGGGDEPPT(0.003)S(0.997)PR;SSEGGVGVGPGGGDEPPT(0.003)S(0.997)PR 324.71 1.3957999999999995e-187 74866900.0 158793.0 131098.0 156211.0 140557.0 169364.0 178661.0 153757.0 152643.0 195091.0 126140.0 True False 156528.58270093004 130794.45063563737 143367.93457189781 150894.0306644066 159402.34250243532 171020.0855091328 161717.785121221 159735.3510306681 173117.79718069456 147943.13092901514 1.0580321081350799 0.8840859985476047 0.9690746280115394 1.0199461760533333 1.0774568680645162 1.155985306213306 1.0931077644883365 1.0797077906057768 1.1701644820789856 1.0 17.1746831874965 -6.113660988591771 2.2331708949057747 1.104767633655486 0.9623537569495524 0.4854977514727763 0.058583385375884915 0.23411393265578662 2.297414255638193 0.018102668120179022 0.025810901538705827 7.697310599116553e-07 6.113660988591771 -0.14241387670593353 SSELDASDSSSS(ph)SNLSLAK ddPTM_PC-9_AZD4547_30min_R2 1 SSELDASDSSSSSNLSLAK 19 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 SSELDAS(0.003)DS(0.12)S(0.12)S(0.084)S(0.552)S(0.12)NLSLAK 139.12 0.00014985 6894100.0 12877.0 23551.0 40612.0 60798.0 58593.0 68085.0 51944.0 80246.0 59726.0 65645.0 True False 16971.618141761042 31163.400185093724 40073.45834459062 46781.96041973639 50458.37333880033 63827.63418692054 56566.91537113835 67845.82456963381 62882.99442695438 63346.7885307829 0.26791599914356845 0.4919491722922955 0.6326044188509606 0.7385056370616648 0.7965419322603933 1.0075906871885696 0.8929721092909086 1.0710223224128346 0.9926784906609253 1.0 15.95098386098097 -5.193942335190386 0.5271940499657393 1.02801326935686 6.695820263463621e-20 0.9549820808744447 0.05244474715410949 0.5290175093313016 0.15336872394751902 0.0323922508733746 0.31807773808030854 6.398197839179658e-06 5.193942335190386 -1.02801326935686 down SSELDASDSSSS(ph)SNLSLAK ddPTM_PC-9_Lapatinib_30min_R1 1 SSELDASDSSSSSNLSLAK 19 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 SSELDASDS(0.002)S(0.002)S(0.002)S(0.497)S(0.497)NLSLAK 161.91 3.2983e-06 7562300.0 44232.0 43191.0 42317.0 42267.0 41450.0 37559.0 35681.0 35342.0 49651.0 35462.0 True False 43601.24356884465 43090.99389314712 38837.85960834382 45375.45617857864 39011.99249383546 35952.6891243053 37528.38759152614 36984.118342314214 44058.78153179112 41591.55944985519 1.048319518324684 1.0360514119481314 0.9337918587825166 1.0909775151202374 0.9379785949327103 0.864422724222486 0.9023077780185711 0.889221727473433 1.0593202590758959 1.0 15.344003158508098 -6.399067199065368 8.702784164043184 0.9300667767725223 1.0210829629293612 0.2815651198155352 0.06466927021022899 0.3903169199251254 25.949561625652017 0.019919751226633402 0.022579110044188107 3.989631653905071e-07 6.399067199065368 0.09101618615683893 SSELDASDSSSSS(ph)NLSLAK ddPTM_PC-9_AZD4547_30min_R2 1 SSELDASDSSSSSNLSLAK 19 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 SSELDASDSSSS(0.002)S(0.998)NLSLAK 281.49 1.0357999999999998e-92 6183600.0 17109.0 34541.0 48877.0 63662.0 73563.0 80899.0 64576.0 85666.0 64461.0 71548.0 True False 22549.30611069267 45705.70276393032 48228.85904433554 48985.7094680953 63350.047239809704 75840.37274124508 70323.13889971185 72428.28810884344 67868.27686026017 69043.12629751634 0.32659740831440054 0.6619877345498254 0.698532375786559 0.7094943710545367 0.9175431449443008 1.0984492853703998 1.0185393198546624 1.0490296716394325 0.9829838319864952 1.0 16.075210171294124 -4.950405639823404 0.5309123400503961 1.0533583422526978 0.013287650818728944 0.897207274773828 0.07355533772773619 1.1272488134578815 0.27644436073110673 0.04774963021287584 0.7130324224363672 1.120970955657702e-05 4.950405639823404 -1.0400706914339688 down SSELDASDSSSSS(ph)NLSLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSELDASDSSSSSNLSLAK 19 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 SSELDASDSSSS(0.032)S(0.968)NLSLAK 250.26 3.6524e-54 3750200.0 18319.0 28219.0 42334.0 47394.0 64730.0 50410.0 50013.0 47189.0 43367.0 44485.0 True False 21420.044883257506 31020.395827126013 43343.403112589054 44738.667833421125 52046.621168193 47766.41085826677 45275.406577236135 45950.33875087841 44001.16033269649 52549.77835693378 0.4076143716109737 0.5903049793364726 0.8248065827830466 0.8513578788009863 0.990425132046739 0.9089745447416172 0.8615717895080749 0.8744154625880626 0.8373234237797823 1.0 15.681397058788724 -5.055468833013294 1.495616558653304 0.9026695890825651 0.3363512852281395 0.9132244892516225 0.05084293690923511 0.1863985457146446 0.5602508591079165 0.015191348927148976 0.13495349599573903 8.800982693556213e-06 5.055468833013294 -0.5663183038544256 down SSELDASDSSSSS(ph)NLSLAK ddPTM_PC-9_Lapatinib_30min_R1 1 SSELDASDSSSSSNLSLAK 19 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 SSELDASDS(0.001)S(0.021)S(0.021)S(0.021)S(0.937)NLSLAK 281.61 8.920699999999999e-93 5622300.0 49427.0 45408.0 51344.0 47139.0 46870.0 45146.0 39368.0 42246.0 51422.0 42317.0 True False 48722.1619161983 45302.86056585923 47122.694513571485 50605.75931109423 44113.198749965435 43215.21082046615 41406.282410896616 44208.903386605394 45630.31286233433 49631.43706614183 0.9816794514990212 0.9127855900179944 0.9494525506237701 1.0196311511926193 0.8888156651836928 0.8707225374690434 0.8342753073161295 0.8907439719645829 0.9193832691470255 1.0 15.598966607671905 -6.302143342501912 24.057724687191957 0.8903781706568803 0.9609203181145197 0.2943877558558752 0.04766661141356024 375.87341447157104 222155.52923037446 0.014609700691055603 0.016566133716636837 4.987198536610172e-07 6.302143342501912 0.07054214745763943 SSEMS(ph)PVPMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSEMSPVPMR 10 0 E9PCH4;Q8TEU7;A0A5F9ZHG7;Q8TEU7-4;B7Z7Y1;Q8TEU7-2;Q8TEU7-5;Q8TEU7-3;D6RE77 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 1 S(0.002)S(0.006)EMS(0.992)PVPMR;S(0.004)S(0.019)EMS(0.977)PVPMR;S(0.002)S(0.001)EMS(0.996)PVPMR;S(0.003)S(0.011)EMS(0.986)PVPMR 70.808 0.020807 39326800.0 100970.0 122721.0 150906.0 159771.0 164759.0 161007.0 161740.0 168676.0 160457.0 119954.0 True False 118062.22675159728 134903.92984516567 154504.17135419216 150819.54885457107 132475.656682378 152563.50948337553 146418.8163038043 164248.43372699473 162803.38007017932 141700.7106446585 0.8331802022338531 0.9520342504383266 1.0903556563074746 1.064352805066587 0.9348976168128466 1.076660157802296 1.0332962737990592 1.1591221595132217 1.1489242314277432 1.0 17.11248746798529 -4.953019306892319 2.5762506467053345 1.0639342381401269 0.8218287328955888 0.574472851883328 0.06276651351149411 0.26759755119219697 2.9940814116763925 0.01766201862177716 0.12091848752415822 1.1142449978797322e-05 4.953019306892319 -0.2421055052445381 SSEMS(ph)PVPMR ddPTM_PC-9_Lapatinib_30min_R1 3 SSEMSPVPMR 10 0 E9PCH4;Q8TEU7;A0A5F9ZHG7;Q8TEU7-4;B7Z7Y1;Q8TEU7-2;Q8TEU7-5;Q8TEU7-3;D6RE77 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 1 S(0.001)S(0.005)EMS(0.993)PVPMR;S(0.009)S(0.007)EMS(0.984)PVPMR;S(0.022)S(0.014)EMS(0.964)PVPMR 79.65899999999999 0.015390000000000001 10576700.0 77851.0 65329.0 72479.0 65002.0 58094.0 51103.0 46288.0 53981.0 67165.0 43580.0 True False 76740.83046387498 65177.73471430183 66520.05639703081 69782.46392031542 54677.02513719844 48917.44381691137 48684.56615107658 56489.154327329095 59600.170421194984 51112.744933300135 1.5014030368358882 1.2751757863788353 1.3014377624178968 1.365265434509112 1.0697336879197064 0.9570498293673421 0.9524936728521972 1.1051872561539189 1.1660530166980967 1.0 15.641395450741262 -6.293219385774161 5.152377337591791 1.0360047756498896 1.3514376625240239 0.7828924463740453 0.08231825023604207 0.09534950289352 7.011317577138267 0.02697399826341674 0.03161462178471359 5.090736452947376e-07 6.293219385774161 0.3154328868741343 SSEPVKETVQTTQS(ph)PTPVEK ddPTM_PC-9_AZD4547_30min_R2 1 SSEPVKETVQTTQSPTPVEK 20 1 A0A0A0MT33;Q9UPN6;Q9UPN6-2 A0A0A0MT33 SCAF8 Protein SCAF8 1 SSEPVKETVQT(0.002)T(0.289)QS(0.598)PT(0.111)PVEK 99.964 0.00015826 7137600.0 16259.0 12515.0 18269.0 17646.0 19534.0 21008.0 17157.0 22449.0 18940.0 18103.0 True False 21429.023791791005 16560.229005836183 18026.74112324746 13577.987327982304 16822.04128138387 19694.3664389928 18683.939762486916 18980.022876700514 19941.12973322364 17469.219480124346 1.226673224649329 0.9479661655563737 1.031914513625376 0.777252088648305 0.9629532275625248 1.1273752935212775 1.0695348915699767 1.086483737770602 1.1415008985325141 1.0 14.092527530030258 -6.754096677586493 24.996247090335366 1.0894189459100214 0.977633897356762 0.15674164099809162 0.10898096257997882 289.19111249582176 984472.2845217994 0.036832567676155385 0.036119458699895794 1.7615838594505338e-07 6.754096677586493 -0.11178504855325944 SSEPVKETVQTTQS(ph)PTPVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSEPVKETVQTTQSPTPVEK 20 1 A0A0A0MT33;Q9UPN6;Q9UPN6-2 A0A0A0MT33 SCAF8 Protein SCAF8 1 SSEPVKETVQTT(0.168)QS(0.663)PT(0.168)PVEK;SSEPVKETVQTTQS(1)PTPVEK 216.19 9.115200000000001e-29 219790000.0 141377.0 124782.0 130864.0 167088.0 164709.0 134133.0 170987.0 136312.0 130575.0 114220.0 True False 165309.3337769691 137169.5323044916 133984.29406448363 157726.60106660478 132435.45382344967 127098.82935234859 154789.87352132224 132733.9544345024 132484.41235136957 134927.1818349774 1.2251744350456424 1.0166189676462425 0.9930118767940549 1.168975731365324 0.98153279437367 0.9419809086933775 1.1472104539368344 0.9837451033168585 0.981895645855885 1.0 17.041821490982507 -4.759632224160014 24.991106674250855 1.026917843409985 1.2251746844024294 0.4221773930599555 0.07056626723753391 46.98477363388533 649566.2094504404 0.01739390054669794 0.10913186029523693 1.7392730828942162e-05 4.759632224160014 0.19825684099244434 SSEPVKETVQTTQS(ph)PTPVEK ddPTM_PC-9_Lapatinib_30min_R1 2 SSEPVKETVQTTQSPTPVEK 20 1 A0A0A0MT33;Q9UPN6;Q9UPN6-2 A0A0A0MT33 SCAF8 Protein SCAF8 1 SSEPVKETVQTT(0.002)QS(0.791)PT(0.208)PVEK;SSEPVKETVQT(0.002)T(0.02)QS(0.781)PT(0.197)PVEK 156.08 4.6808999999999995e-06 196225000.0 103602.0 108093.0 118340.0 115848.0 115367.0 127702.0 119388.0 112976.0 130197.0 101827.0 True False 102124.61648172002 107842.71729971426 108610.54200561019 124367.84837759935 108581.33988024894 122240.48314790167 125569.32647002953 118225.27739916483 115532.84282480944 119427.66127405138 0.8551169418563263 0.902996141339877 0.9094253445722337 1.0413655182630739 0.9091808273050468 1.0235525157559244 1.0514258181937 0.9899321157087098 0.9673876352622826 1.0 16.865777499992888 -5.345244119487925 1.150694280513438 0.9997414784504207 0.8462431797023321 0.5834250175645472 0.041178442204980896 0.5347047779061059 1.0799706095784818 0.013793517785917777 0.07846712388381046 4.516020248569523e-06 5.345244119487925 -0.15349829874808862 SSEPVKETVQTTQSPT(ph)PVEK ddPTM_PC-9_AZD4547_30min_R2 2 SSEPVKETVQTTQSPTPVEK 20 1 A0A0A0MT33;Q9UPN6;Q9UPN6-2 A0A0A0MT33 SCAF8 Protein SCAF8 1 SSEPVKETVQTTQS(0.493)PT(0.507)PVEK;SSEPVKETVQTT(0.001)QS(0.213)PT(0.786)PVEK 155.2 1.4896e-05 327000000.0 221110.0 211871.0 266560.0 274230.0 253840.0 297940.0 262770.0 298040.0 256290.0 258250.0 True False 291418.38062629336 280354.1573867774 263025.2402327897 211010.51031126507 218598.69759734202 279309.7647007583 286156.0209470585 251984.76627786612 269836.96617359517 249208.74610518204 1.1693746113681587 1.124977199911154 1.055441449562032 0.8467219293427412 0.8771710504296641 1.1207863651096406 1.1482583393212145 1.0111393368654582 1.0827748640078094 1.0 17.92699517578891 -5.276456057043765 3.508803182255451 1.0138443640894808 1.1537827543952603 0.254806190423004 0.0907195978097461 0.3564294288899312 9.408625113838852 0.02726070490306072 0.07273668604481423 5.291075308689029e-06 5.276456057043765 0.1399383903057796 SSEPVKETVQTTQSPT(ph)PVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSEPVKETVQTTQSPTPVEK 20 1 A0A0A0MT33;Q9UPN6;Q9UPN6-2 A0A0A0MT33 SCAF8 Protein SCAF8 1 SSEPVKETVQTT(0.052)QS(0.203)PT(0.746)PVEK;SSEPVKETVQT(0.001)T(0.014)QS(0.408)PT(0.576)PVEK;SSEPVKETVQTT(0.003)QS(0.343)PT(0.654)PVEK 152.07 7.679400000000001e-06 57332000.0 170196.0 161167.0 174580.0 209958.0 213282.0 186969.0 225828.0 174761.0 162170.0 155400.0 True False 199006.82127577366 177166.59464440378 178742.6492983371 198194.73395302004 171490.923157648 177164.01649988658 204435.9369868651 170173.70892458555 164541.42945450166 183572.7898542768 1.0840758122908556 0.9651026973280824 0.973688145395764 1.0796520231040252 0.9341848718090541 0.9650886530652085 1.1136505423769492 0.9270094389243216 0.8963279883969593 1.0 17.485992705021232 SSEPVKETVQTTQSPT(ph)PVEK ddPTM_PC-9_Lapatinib_30min_R1 2 SSEPVKETVQTTQSPTPVEK 20 1 A0A0A0MT33;Q9UPN6;Q9UPN6-2 A0A0A0MT33 SCAF8 Protein SCAF8 1 SSEPVKETVQT(0.001)T(0.167)QS(0.119)PT(0.712)PVEK;SSEPVKETVQTTQS(0.205)PT(0.794)PVEK 149.86 7.837399999999999e-05 143189000.0 167528.0 208755.0 202882.0 196943.0 217206.0 196869.0 186662.0 182293.0 202854.0 174669.0 True False 165139.01999912734 208271.6406233686 186201.82510716765 211426.84520258877 204430.3701234265 188449.37179405367 196326.44501581948 190762.9982733148 180006.4463726805 204860.30391818698 0.8061055111246797 1.016652014274781 0.9089209649006926 1.0320537515507358 0.9979013318513273 0.9198920834819849 0.9583430330857285 0.9311857623207369 0.8786789970035771 1.0 17.64428093273132 -4.747546988513119 24.98068285489035 0.958724395245317 0.8061051254634163 0.48064281020199473 0.04808891537001467 645.5284537603488 1160693.6562370458 0.011935868796392206 0.24192671337658314 1.7883520278032206e-05 4.747546988513119 -0.15261926978190077 SSEPVQADESQS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 SSEPVQADESQSPR 14 0 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 SSEPVQADESQS(1)PR;SSEPVQADESQS(1)PR 212.35 7.2722e-12 35076000.0 12786.4 20842.4 22345.5 29168.0 28060.0 27089.0 19388.9 32947.0 26176.0 20255.6 True False 16852.209226358103 27579.298204653627 22049.18406970967 22443.76824110777 24164.353350856545 25395.12054769022 21114.47453872372 27855.798196741584 27559.609920636874 19546.45760932481 0.8621618076882948 1.4109614517311146 1.1280398991166007 1.1482268905032067 1.2362523089262336 1.299218562015823 1.0802200051149358 1.4251072369989295 1.4099541958686836 1.0 14.254619552170247 -4.744740330769696 24.975365641589562 1.2415939441436192 0.8621606900543247 0.38768752885677593 0.14144891281298758 1043.9923862913413 1561327.478789708 0.034395965654223544 0.9459580806576713 1.7999468005444818e-05 4.744740330769696 -0.3794332540892945 SSEPVQADESQS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSEPVQADESQSPR 14 0 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 SSEPVQADES(0.001)QS(0.999)PR;SSEPVQADES(0.001)QS(0.999)PR 189.59 2.7499e-06 28435000.0 22839.6 25408.2 29563.0 36219.0 41208.0 29483.0 35194.0 27476.8 23922.1 27452.0 True False 26705.893177337635 27930.558179056072 30267.894038301827 34189.766853582325 33133.58821410315 27936.85957814481 31860.169537505233 26755.56311407607 24271.91545633312 32428.830290087586 0.8235231717716546 0.8612878703674216 0.9333637312090691 1.054301575102849 1.0217324497279503 0.8614821850877605 0.9824643458461043 0.8250548316031724 0.7484671892020798 1.0 14.984989366182383 -7.773058355059933 24.974692129012137 0.8400707243783877 0.9364089931583008 0.1208190029356131 0.09027934963160576 399.0306885580739 857692.7491128885 0.05034321979306095 0.02450314909952771 1.6863264227144648e-08 7.773058355059933 0.09633826877991314 SSEPVQADESQS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 SSEPVQADESQSPR 14 0 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 SSEPVQADES(0.018)QS(0.982)PR;SSEPVQADES(0.004)QS(0.996)PR 189.8 2.5956e-06 31812000.0 23054.6 25755.4 30255.6 23133.3 25714.1 25029.7 24460.7 24660.1 26326.2 22890.0 True False 22725.837176304154 25695.764953707043 27768.10135799342 24834.60005242656 24201.64719386573 23959.238078080463 25727.155358875698 25805.898272121074 23361.066128823968 26846.50600099219 0.846510051455644 0.9571362825671759 1.0343283165774781 0.9250589276499789 0.9014821963413522 0.8924527488677663 0.9583055373360271 0.9612386159736147 0.8701715645216771 1.0 14.712446717181042 -10.65386578247485 4.673663194721344 1.0000059482972896 0.9314722161520452 0.14877882016012178 0.051267413714482936 3.2565057006174154e-06 6.054555120597774e-07 0.05087237647879763 0.012337292813351112 2.218882053295033e-11 10.65386578247485 -0.06853373214524439 SSEPVQHEES(ph)IRKPSPEPR ddPTM_PC-9_AZD4547_30min_R2 1 SSEPVQHEESIRKPSPEPR 19 2 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 SSEPVQHEES(0.5)IRKPS(0.5)PEPR 48.623000000000005 0.022775999999999998 161400000.0 268690.0 228990.0 476620.0 765410.0 640690.0 532790.0 433800.0 585940.0 454860.0 538440.0 True False 354127.83090081264 303006.5393564862 470299.7073820243 588956.5499666168 551741.2526144083 499474.557074971 472407.3596180473 495396.4365617129 478902.9709849055 519589.37948838 0.6815532512414109 0.5831653827390492 0.9051372602055697 1.1335038267074282 1.0618793886004503 0.9612870793602145 0.9091936407230051 0.9534383421183685 0.9216950728601557 1.0 18.987012416546627 -5.367493419873869 4.395291089224481 0.9895633436137689 0.6336332101603283 0.8133253565121882 0.06759979680399934 0.09183875250256046 2.9195469295373835 0.019768606055193313 0.043777087313300364 4.2904868983519925e-06 5.367493419873869 -0.3559301334534406 SSEPVQHEESIRKPS(ph)PEPR ddPTM_PC-9_AZD4547_30min_R2 1 SSEPVQHEESIRKPSPEPR 19 2 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 SSEPVQHEES(0.101)IRKPS(0.899)PEPR 69.111 0.0025475000000000003 156230000.0 267500.0 359380.0 587840.0 1027500.0 774030.0 648430.0 458370.0 767360.0 542830.0 582370.0 True False 352559.4356543506 475542.55694106297 580044.8575121673 790625.7497167533 666569.2952303444 607883.5695942544 499164.04201964964 648782.1441785777 571522.8855905904 561981.4035596332 0.6273507155596469 0.8461891335352737 1.032142440725118 1.4068539362848473 1.1861056095597533 1.081679154761836 0.8882216366198356 1.154454827275675 1.016978287841058 1.0 19.100162865672715 -5.064717963149548 2.3594790528523872 1.1095294315697715 0.6297432027276355 0.5736670838995828 0.13079637912622222 0.2653109258261588 2.5644691747594988 0.03797958793394796 0.20257575371067638 8.615530750462517e-06 5.064717963149548 -0.47978622884213595 SSEPVQHEESIRKPS(ph)PEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSEPVQHEESIRKPSPEPR 19 2 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 SSEPVQHEES(0.243)IRKPS(0.756)PEPR;SSEPVQHEES(0.185)IRKPS(0.814)PEPR;SSEPVQHEES(0.026)IRKPS(0.974)PEPR 77.505 0.0095367 207791000.0 320705.3 261144.9 370897.0 491538.0 556060.0 508560.0 427574.0 446391.0 455182.0 353149.4 True False 374994.3730715953 287069.63982548093 379740.5911147063 463998.7194476982 447104.03471011034 481890.21833128686 387071.09535231197 434673.7092403603 461838.1756302588 417172.5906908884 0.898895041140069 0.6881315940485419 0.9102721501568687 1.1122464174342328 1.071748347535613 1.1551339399676719 0.9278440242473153 1.0419517459679888 1.1070674007259171 1.0 18.670284846644087 -5.556238640981342 4.602501729097438 1.0590433498086567 0.792782922018421 0.6674417836312881 0.07629325821587732 0.10349391220636174 5.158519866411096 0.020458715686895362 0.03815367882936609 2.7781862594512515e-06 5.556238640981342 -0.2662604277902356 SSEPVQHEESIRKPS(ph)PEPR ddPTM_PC-9_Lapatinib_30min_R1 2 SSEPVQHEESIRKPSPEPR 19 2 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 SSEPVQHEESIRKPS(1)PEPR;SSEPVQHEES(0.073)IRKPS(0.927)PEPR 65.905 0.010707 100936100.0 263262.0 215366.0 297110.0 242670.0 253179.0 264951.0 167156.0 197061.0 267183.0 174057.0 True False 259507.8356036618 214867.3332590472 272682.762677766 260516.7613233889 238287.5089890653 253619.66336094745 175810.51977941045 206217.17346654885 237090.03697827947 204142.52053362553 1.2712091284329798 1.0525359082340473 1.335747016177606 1.2761513899328858 1.167260541146378 1.2423656899012974 0.8612146030128576 1.0101627673034514 1.1613946783772906 1.0 17.639217184852093 -7.23713890942392 24.613605238623148 1.0090398989843217 1.2212501980155126 0.5393823614217719 0.09777121866711579 512.4346433977885 519038.3607813304 0.037584848512366764 0.029096342158095225 5.792433953487931e-08 7.23713890942392 0.21221029903119093 SSEPVREDSSGMHHENQTYPPYS(ph)PQAQPQPIHR ddPTM_PC-9_AZD4547_30min_R2 1 SSEPVREDSSGMHHENQTYPPYSPQAQPQPIHR 33 1 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 S(0.001)S(0.001)EPVREDS(0.004)S(0.004)GMHHENQT(0.029)Y(0.027)PPY(0.253)S(0.679)PQAQPQPIHR 40.775 0.022279 7620500.0 1655.3 3175.0 5461.2 11165.0 8702.3 5357.9 7246.1 7718.5 3226.5 7269.2 True False 2181.6509676211117 4201.256659491003 5388.780919715309 8591.081747530458 7494.135857632177 5022.869666007212 7890.988862444283 6525.783178485138 3397.046202969701 7014.707520572277 0.31101096677557943 0.5989211449187056 0.7682117756031087 1.224724155973017 1.068346162067893 0.7160483386194603 1.124920581407294 0.930300110068274 0.4842748173045085 1.0 12.776167236345232 -5.088644711790052 2.005498151918091 0.9361359058579214 0.3053162953614589 0.4849399322295487 0.2026206016336342 0.3691213564803036 2.431563743897104 0.05716623928225129 0.3394431494226846 8.153710510875691e-06 5.088644711790052 -0.6308196104964625 SSEPVREDSSGMHHENQTYPPYS(ph)PQAQPQPIHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSEPVREDSSGMHHENQTYPPYSPQAQPQPIHR 33 1 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 S(0.008)S(0.008)EPVREDS(0.05)S(0.019)GMHHENQT(0.062)Y(0.056)PPY(0.376)S(0.422)PQAQPQPIHR 43.835 0.0083855 11453000.0 2117.7 2380.4 4180.0 13595.0 17339.0 20255.0 11169.0 15166.0 15914.0 8468.7 True False 2476.184783518445 2616.7103804844533 4279.667052738278 12833.31622558468 13941.54741905296 19192.79214311037 10110.991463442519 14767.908569705263 16146.712143669893 10004.008271807683 0.24751926590230702 0.26156619520783586 0.42779523331651137 1.2828174344627719 1.3935961506890857 1.91851022326697 1.0106940327045035 1.4761991562244843 1.614024269569326 1.0 13.288290535072912 -5.756182223710827 3.1584940085363984 1.428498073037963 0.26424493186867504 0.7932069557527557 0.25242924134190514 0.10021537796043323 2.06319597021124 0.07130013698734244 0.1242173575025951 1.7531447532043838e-06 5.756182223710827 -1.164253141169288 SSEQGLDEHINVS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 SSEQGLDEHINVSPK 15 0 O95171-2;O95171;O95171-3 O95171-2 SCEL Sciellin 1 SSEQGLDEHINVS(1)PK;SSEQGLDEHINVS(1)PK;SSEQGLDEHINVS(1)PK;SSEQGLDEHINVS(1)PK 124.5 2.9066999999999998e-05 207041100.0 428090.0 447918.0 414698.0 478034.0 510838.0 438608.0 420562.0 440962.0 440893.0 491188.0 True False 564213.7151748459 592698.7339861079 409198.83356113994 367830.64685167663 439916.9614057325 411181.7724235406 457991.2032634502 372821.4551987006 464197.7038791009 473991.65762599127 1.1903452436288349 1.250441277710807 0.8633038724998471 0.7760276809384644 0.9281111899924074 0.8674873614505436 0.9662431730493315 0.7865569977876695 0.9793372866603943 1.0 18.85450214198329 -5.262139234530967 24.999858239032253 0.8866296040607667 1.2203932856792 0.7549430618708743 0.07380393454296735 24.88025652653857 888799.9042313946 0.01810019103570917 0.04170860492603418 5.468406180380806e-06 5.262139234530967 0.3337636816184332 SSEQGLDEHINVS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSEQGLDEHINVSPK 15 0 O95171-2;O95171;O95171-3 O95171-2 SCEL Sciellin 1 SSEQGLDEHINVS(1)PK;SSEQGLDEHINVS(1)PK;SSEQGLDEHINVS(1)PK;SSEQGLDEHINVS(1)PK 180.78 1.922e-05 111361600.0 342114.0 329812.0 295456.0 388258.0 398276.0 383977.0 419267.0 342438.0 301819.0 317648.0 True False 400027.14314049756 362553.55570842576 302500.79156311945 366505.163009419 320236.6768481875 363840.5701671236 379550.9945297842 333449.36534305185 306232.53188955074 375235.0678998156 1.0660707843204602 0.9662038192155971 0.8061634357796336 0.9767348373400766 0.8534295012471698 0.9696337077542703 1.0115019277226 0.88864126481931 0.8161085092700133 1.0 18.51743513683438 -4.866908460417785 3.9649801908772653 0.9150776445797759 1.0678736700138007 0.29556273167620706 0.07057522843453672 0.27732218390084085 7.234473052970408 0.017593223814890157 0.09994873991721777 1.3585997789158146e-05 4.866908460417785 0.15279602543402482 SSEQGLDEHINVS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 SSEQGLDEHINVSPK 15 0 O95171-2;O95171;O95171-3 O95171-2 SCEL Sciellin 1 SSEQGLDEHINVS(1)PK;SSEQGLDEHINVS(1)PK;SSEQGLDEHINVS(1)PK;SSEQGLDEHINVS(1)PK 94.845 0.0016739 192772000.0 657629.0 518651.0 464394.0 528626.0 569021.0 529048.0 484312.0 514631.0 522747.0 446167.0 True False 648251.0898656127 517450.09547532257 426213.3179326797 567502.9194846414 535552.3035183287 506421.8503111228 509387.30560318474 538542.6350128315 463869.7280900531 523286.3714698418 1.2388075157485214 0.9888468794283216 0.8144934421576913 1.0844978016350801 1.023440190146809 0.9677719083121755 0.9734388919252446 1.0291547121705786 0.8864548235550349 1.0 18.99724116016393 -4.764806263005882 6.068559280229191 0.9742590841888005 1.2477087042150983 0.5507172870748493 0.07179797117260642 0.09641424755897565 14.102508666853938 0.017702346987554712 0.10962686839383776 1.7186749100294352e-05 4.764806263005882 0.2734496200262978 SSFASSSASDASKPS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 2 SSFASSSASDASKPSSPR 18 1 Q96IF1 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 SSFASSSASDAS(0.004)KPS(0.498)S(0.498)PR;SSFASSSASDAS(0.004)KPS(0.864)S(0.131)PR 82.837 0.0011756 117701000.0 68735.0 67204.0 90552.0 133505.0 112110.0 89634.0 76896.0 98562.0 82097.0 89537.0 True False 90591.30022318423 88926.37875415235 89351.22131437436 102727.48488168848 96545.46165946299 84029.17181039038 83739.5950327093 83331.50762944242 86436.47981565268 86402.3368829418 1.0484820606868266 1.0292126574612226 1.034129683730982 1.1889433618081886 1.1173941023176621 0.9725335545522734 0.9691820621259354 0.9644589560388888 1.00039516214425 1.0 16.39878271235299 -6.77085866948943 24.99582378277222 0.9783343662323652 1.0837095172423643 0.5646647013664996 0.04488193501616071 164.74463883843478 437177.9377071232 0.017574349051012485 0.01570290110927633 1.6948892709450793e-07 6.77085866948943 0.10537515100999906 SSFASSSASDASKPS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSFASSSASDASKPSSPR 18 1 Q96IF1 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 SSFASSSASDAS(0.007)KPS(0.496)S(0.496)PR;SSFASSSASDASKPS(0.5)S(0.5)PR;SSFAS(0.002)S(0.002)S(0.002)ASDAS(0.194)KPS(0.718)S(0.082)PR;SSFAS(0.041)S(0.051)S(0.057)AS(0.009)DAS(0.05)KPS(0.396)S(0.396)PR 109.42 0.00011757 63864500.0 110684.0 110765.0 108462.0 140159.0 154181.0 132971.0 155732.0 153763.0 147291.0 100612.0 True False 129420.61509135198 121761.0171796168 111048.14542442583 132306.345631609 123970.3398475695 125997.76667793284 140979.93755795763 149726.8841753653 149444.8522278044 118852.15915584612 1.0889210260088575 1.0244745913278395 0.934338477425663 1.1132010269844652 1.0430634220537138 1.0601218149744926 1.1861790190373926 1.2597742038412139 1.2574012393989686 1.0 16.858808587015744 -7.241945358331686 3.8100171218750125 1.1996576234546446 1.0392898441002827 0.37655663142184914 0.08125465558973552 0.20635546574042163 6.726748876397168 0.03321126820107188 0.02369941230392042 5.728681030499893e-08 7.241945358331686 -0.16036777935436186 SSFASSSASDASKPSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 SSFASSSASDASKPSSPR 18 1 Q96IF1 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 SSFASSSAS(0.001)DAS(0.006)KPS(0.473)S(0.521)PR;SSFASSSASDASKPS(0.056)S(0.944)PR 114.53 6.6243e-05 115675000.0 106981.0 88749.0 111318.0 145713.0 122406.0 126204.0 119013.0 113162.0 95356.0 126482.0 True False 140998.73265696506 117435.37866871389 109841.85058611087 112121.11909340853 105412.03978135958 118312.44392929564 129604.9264412692 95675.41310406644 100396.32348686771 122053.90367812467 1.1552169034167141 0.9621599566238328 0.8999454116255151 0.9186196894536822 0.8636515228496722 0.9693458411727998 1.0618662946091242 0.7838783539146568 0.822557251029255 1.0 16.897158912341695 -4.757406315951726 2.824618978697956 0.9130062879764449 1.207924561257181 0.46044463814638237 0.07775095470200465 0.4409211718822475 4.61102436737363 0.02082669492105432 0.31334354512361834 1.7482103378011554e-05 4.757406315951726 0.29491827328073605 SSFASSSASDASKPSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSFASSSASDASKPSSPR 18 1 Q96IF1 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 SSFASSSASDAS(0.005)KPS(0.258)S(0.737)PR;SSFAS(0.001)S(0.001)S(0.001)ASDAS(0.002)KPS(0.184)S(0.811)PR 75.703 0.0026973 103891000.0 117519.0 131408.0 133216.0 170459.0 156265.0 154467.0 167976.0 182045.0 156758.0 117651.0 True False 137412.64559394814 144453.31779478252 136392.37466449334 160908.73486553418 125645.99500768837 146366.47859638755 152064.09723907456 177266.5116426211 159050.2891930003 138980.19497519673 0.9887210592737451 1.0393805953471467 0.9813799346650418 1.1577817608778787 0.9040568336381448 1.0531463034895656 1.0941422068533784 1.2754803781521329 1.1444097428513853 1.0 17.08451978438699 -7.376257532821307 3.3039542772198227 1.160232094117495 1.0201457948957673 0.26336127557832834 0.08743802193530316 0.2850297771914699 5.830945411414122 0.038501516283449305 0.02451177842799835 4.2047721513859864e-08 7.376257532821307 -0.14008629922172777 SSFASSSASDASKPSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 SSFASSSASDASKPSSPR 18 1 Q96IF1 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 SSFASSSASDASKPS(0.169)S(0.831)PR;SSFASSSASDASKPS(0.009)S(0.991)PR;SSFASSSASDASKPS(0.012)S(0.988)PR;SSFASSSASDAS(0.004)KPS(0.035)S(0.96)PR 112.53 8.3176e-05 257879000.0 396636.0 321494.0 332110.0 303374.0 351319.0 321857.0 344784.0 276924.0 326653.0 295089.0 True False 390979.8979058661 320749.60039553314 304805.1977816733 325685.13598599634 330655.10713972955 308091.9263953125 362635.2284789314 289790.90000076534 289861.8993314167 346094.74046862393 1.129690377196909 0.9267682021438043 0.8806987282411654 0.941028851074153 0.9553889975097899 0.8901953435586615 1.0477917924667421 0.8373166827336893 0.83752182693945 1.0 18.400807491763665 -4.761874725824796 6.9999709491585245 0.921669253511289 1.134100268152452 0.48471169471272624 0.06357689818436375 0.09348784252783458 26.575678472956493 0.015669651628646253 0.09460125943734385 1.7303154044112075e-05 4.761874725824796 0.21243101464116287 SSFFSDRGS(ph)GSR ddPTM_PC-9_AZD4547_30min_R2 4 SSFFSDRGSGSR 12 1 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDH3;A0A2R8YF89;A0A2R8YCU0;A0A2R8Y650;A0A087WX09 A0A2R8Y5G6 DDX3X ATP-dependent RNA helicase DDX3X 1 SSFFS(0.001)DRGS(0.907)GS(0.092)R;SSFFS(0.043)DRGS(0.919)GS(0.038)R;SSFFS(0.013)DRGS(0.974)GS(0.013)R;SSFFS(0.008)DRGS(0.865)GS(0.127)R 75.483 0.009293000000000001 160667000.0 75931.0 77291.0 85616.0 190860.0 177314.0 110073.0 102404.0 169659.0 107463.0 126975.0 True False 100075.47853708596 102273.80424211637 84480.67589949942 146860.17575760518 152697.01176242955 103190.11790933232 111517.75761716581 143442.0999259714 113143.27478993722 122529.64389818184 0.8167450369826051 0.8346862113392135 0.6894713247489735 1.1985685348081254 1.246204648152865 0.8421645132265295 0.9101287987895685 1.1706726255171942 0.9233951164010206 1.0 16.902771300653285 -5.7533614008666865 24.99999150097307 1.0434405590522409 0.7857393783619703 0.4594111792759593 0.12983560674719047 174.5509841587226 540200.202711507 0.037314438274612956 0.06322028906628488 1.7645688125859812e-06 5.7533614008666865 -0.2577011806902706 SSFFSDRGS(ph)GSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SSFFSDRGSGSR 12 1 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDH3;A0A2R8YF89;A0A2R8YCU0;A0A2R8Y650;A0A087WX09 A0A2R8Y5G6 DDX3X ATP-dependent RNA helicase DDX3X 1 SSFFS(0.042)DRGS(0.897)GS(0.061)R;SSFFS(0.007)DRGS(0.937)GS(0.056)R;SSFFS(0.006)DRGS(0.871)GS(0.122)R;SSFFS(0.003)DRGS(0.629)GS(0.368)R;SSFFS(0.001)DRGS(0.995)GS(0.004)R;SSFFS(0.037)DRGS(0.925)GS(0.038)R 72.209 0.012066 132599800.0 202529.0 133734.0 167605.0 157359.0 198134.0 164744.0 106989.0 198047.0 100068.0 90864.0 True False 236813.15956991375 147010.2277027842 171601.33884550238 148542.68539476133 159311.06501681998 156104.53462476307 96854.22738671768 192848.47609814195 101531.30518994335 107336.92392097178 2.206259979504076 1.3696146892659455 1.5987167563311775 1.383891767795841 1.484214929935153 1.4543414225257385 0.9023383924997505 1.7966648293380307 0.9459121938755867 1.0 16.71178692326366 -2.048730796602683 0.9609452852256404 1.3176848261980554 199.99999999999997 0.46861970008020315 0.2794832525105321 367.8645265054904 1.9201496266797693 0.08431508671447865 159003.76625597413 0.008938593830554696 2.048730796602683 198.68231517380192 SSFFSDRGS(ph)GSR ddPTM_PC-9_Lapatinib_30min_R1 4 SSFFSDRGSGSR 12 1 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDH3;A0A2R8YF89;A0A2R8YCU0;A0A2R8Y650;A0A087WX09 A0A2R8Y5G6 DDX3X ATP-dependent RNA helicase DDX3X 1 SSFFS(0.008)DRGS(0.982)GS(0.009)R;SS(0.001)FFS(0.054)DRGS(0.912)GS(0.034)R;SSFFS(0.019)DRGS(0.942)GS(0.039)R;SSFFSDRGS(0.764)GS(0.236)R 82.48299999999999 0.005692 164448000.0 200429.0 167222.0 178693.0 165014.0 113399.0 85974.0 87377.0 89671.0 112556.0 110690.0 True False 197570.84570582325 166834.80773308867 164001.55131492726 177149.68003056708 106729.09377101186 82297.09243518271 91900.95352105547 93837.44202007994 99878.7580127747 129822.61901484612 1.5218522566027546 1.2850981516095432 1.263274093216164 1.364551735089467 0.8221147792343232 0.6339195208022376 0.7078963143591023 0.7228127327284083 0.7693478899956014 1.0 16.986182240652248 -6.29933721957157 4.528635785359775 0.7452160659359064 1.3495388431769075 0.8682574070957035 0.11104623219954297 0.06716055072530841 3.274738855944978 0.03379980376287969 0.0397514421084627 5.019526835728304e-07 6.29933721957157 0.6043227772410011 SSFLS(ph)SPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSFLSSPER 9 0 Q4AC94 Q4AC94 C2CD3 C2 domain-containing protein 3 1 S(0.001)S(0.001)FLS(0.612)S(0.386)PER 76.17 0.024906 3531400.0 27860.0 25898.0 31074.0 38950.0 40824.0 39407.0 34130.0 36770.0 32222.0 23166.0 True False 32576.147739917786 28468.982286080627 31814.922008801255 36767.757777603794 32824.830257536094 37340.42754794123 30896.95932019816 35804.826461035394 32693.185791965 27365.812418044887 1.1903957844290867 1.0403119721491738 1.1625791159710883 1.343565366009719 1.199483127198941 1.3644918330039832 1.1290349743033703 1.3083779832323144 1.1946725824374673 1.0 14.740087066501811 -5.529232457865098 24.961361870337164 1.2356311628018593 1.1118767794366438 0.12455185720728312 0.10709939228882606 223.3181575702657 877331.0700367792 0.026622808771306582 0.04627092405655528 2.956429602157679e-06 5.529232457865098 -0.12375438336521549 SSFLSS(ph)PER ddPTM_PC-9_AZD4547_30min_R2 2 SSFLSSPER 9 0 Q4AC94 Q4AC94 C2CD3 C2 domain-containing protein 3 1 SSFLS(0.049)S(0.951)PER;SSFLS(0.101)S(0.898)PER 94.40899999999999 0.005756600000000001 16575900.0 104969.0 94679.0 132856.0 185952.0 175078.0 146214.0 117932.0 146861.0 114371.0 131602.0 True False 138346.9585091645 125282.1352012436 131094.24263343177 143083.6393297612 150771.44176626016 137071.2154660557 128427.71953544377 124167.00698004864 120416.41756697584 126994.65403653156 1.089391987078191 0.9865150320831982 1.0322815840399149 1.1266902564938006 1.187226682178991 1.079346343402971 1.0112844553165203 0.977734125283183 0.9482006819935632 1.0 16.954408241061678 -7.420082429373529 2.9836873550027714 0.9738971259224504 1.0834826480347588 0.4851954344312447 0.051077655433029064 0.27145178938063297 4.641659524590584 0.028419630058190985 0.01734303051395223 3.8011724297485907e-08 7.420082429373529 0.10958552211230843 SSFLSS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 1 SSFLSSPER 9 0 Q4AC94 Q4AC94 C2CD3 C2 domain-containing protein 3 1 SSFLS(0.083)S(0.917)PER 109.44 0.0023686 10104000.0 60720.0 49160.0 70900.0 52568.0 58691.0 59356.0 52750.0 55773.0 68416.0 42606.0 True False 59854.121665315724 49046.17304038138 65070.8756819145 56434.026081707336 55238.91077094565 56817.48224559402 55481.136892267736 58364.41718934675 60710.269627580885 49970.39033107353 1.1977917576540542 0.9815047013927878 1.3021886611410136 1.12934931482043 1.1054328454303857 1.1370229823932894 1.1102802384508772 1.1679800138173722 1.2149248630109035 1.0 15.60878586691492 -5.225055710318486 24.99998076317314 1.1482716498871435 1.0896483637352106 0.0606849910910946 0.08812444196067837 1684.6771186636215 1157571.9077335675 0.021002396160124188 0.05556473576671641 5.95585738230805e-06 5.225055710318486 -0.05862328615193291 SSFLVDCSK ddPTM_PC-9_Lapatinib_30min_R1 1 SSFLVDCSK 9 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;A0A0A0MT44 O75369-2 FLNB Filamin-B 0 108.57 0.011181 6790900.0 36765.0 41492.0 39415.0 39193.0 39319.0 37491.0 42914.0 32533.0 37677.0 34306.0 False True 36240.724358124746 41395.92782326089 36174.45084629988 42075.38396401529 37006.33372412826 35887.597325789575 45135.876940185335 34044.60194755555 33433.41950360101 40235.74639012838 0.9007096328407173 1.0288345945389783 0.8990625026698916 1.0457214725445794 0.9197377219080882 0.8919331824448123 1.1217855014430447 0.8461282566366958 0.8309382204427982 1.0 15.29619017509469 SSFS(ph)HYSGLK ddPTM_PC-9_AZD4547_30min_R2 1 SSFSHYSGLK 10 0 Q8NC51;Q8NC51-3 Q8NC51 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 S(0.009)S(0.009)FS(0.981)HYSGLK 81.709 0.0090185 7563800.0 9823.9 19737.0 76642.0 113400.0 91571.0 77810.0 39108.0 172460.0 61653.0 81974.0 True False 12947.695850186083 26116.599271928782 75625.67700300676 87257.382012535 78857.94728051599 72944.52839956338 42588.53623776528 145810.2697365483 64911.85171290591 79104.11521094372 0.16367916910086144 0.3301547486156025 0.9560270891260062 1.1030700713843937 0.9968880515284029 0.9221331684836519 0.5383858491330844 1.8432703450095105 0.8205875451587837 1.0 16.27146512911463 -5.234682260059823 3.0972843076493843 1.0418664110772011 0.1888524192332529 0.5028641599115389 0.3111435186857649 0.20378818646358568 3.9328029935209967 0.082289696620658 0.2513816502040207 5.825292538486643e-06 5.234682260059823 -0.8530139918439482 SSFS(ph)QHAR ddPTM_PC-9_AZD4547_30min_R2 1 SSFSQHAR 8 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 SSFS(1)QHAR 63.32 0.033143 25038000.0 1405.5 660.35 3704.4 6857.0 6542.7 5580.2 2618.0 6607.0 3202.0 5359.9 True False 1852.419763783888 873.7952236519317 3655.277235588036 5276.224589593939 5634.359040222702 5231.269211865371 2850.9969282619795 5586.039963756083 3371.25118298744 5172.25153242659 0.3581457228385827 0.16893904292430767 0.7067091019591507 1.0201020883295229 1.0893435875844406 1.0114104426416195 0.5512100311417799 1.0800016064058977 0.6517956758003607 1.0 12.33657672140356 -5.420288541274244 3.7642478813364475 0.9126407358715596 0.267258075933223 0.6803348768776808 0.17592314774430015 0.12854213811941012 3.2517614638927816 0.04719384698996681 0.10538890689772766 3.7993688586150775e-06 5.420288541274244 -0.6453826599383365 SSFTVDCSK ddPTM_PC-9_Lapatinib_30min_R1 1 SSFTVDCSK 9 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 110.76 0.010508 7492000.0 51539.0 38558.0 43026.0 39665.0 49652.0 40532.0 43047.0 44172.0 39748.0 45038.0 False True 50804.04440890493 38468.721319996475 39488.56836516298 42582.09641856113 46731.56697958786 38798.54084470678 45275.76302941136 46224.39237781406 35271.161675004194 52822.75829063726 0.9617832550389526 0.7282603666460747 0.7475673297462442 0.8061316333438939 0.884686231689475 0.7345042572603361 0.8571260663878737 0.8750847906025999 0.6677266166400845 1.0 15.688872017448336 -11.041567641945166 3.2044930000841894 1.0055488332022346 0.8065285974968808 0.3191369320708962 0.08457463007252777 69544700.57504521 86917699.61461192 3380146.6981378826 0.019773865796682208 9.087247529498195e-12 11.041567641945166 -0.19902023570535388 SSFYSGGWQEGSS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSFYSGGWQEGSSSPR 16 0 D3DPQ1;Q96BR9-2;Q96BR9 D3DPQ1 ZBTB8A Zinc finger and BTB domain-containing protein 8A 1 SSFYSGGWQEGS(0.098)S(0.451)S(0.451)PR 143.28 2.863e-05 3690100.0 23646.0 24797.0 27482.0 17855.0 23986.0 24828.0 19774.0 20682.0 23295.0 20272.0 True False 23308.80370385467 24739.584070023153 25222.536043587803 19168.116262533942 22575.19063829039 23766.164316894825 20797.80096507492 21642.96122335303 20671.27179277504 23775.988189257925 0.9803505754762138 1.040528110675988 1.060840703772869 0.8061964074828303 0.9494953672836168 0.9995868153918608 0.874739707957604 0.9102865063304245 0.8694179870981931 1.0 14.537217683878803 -5.7328982643458986 24.999896440273478 0.9151364655935804 1.0285686765966384 0.4300090549568776 0.058853457201241355 199.59647249159164 174830.17291686204 0.015814575766738094 0.027385320839546742 1.8497018701430972e-06 5.7328982643458986 0.113432211003058 SSFYSGGWQEGSSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 SSFYSGGWQEGSSSPR 16 0 D3DPQ1;Q96BR9-2;Q96BR9 D3DPQ1 ZBTB8A Zinc finger and BTB domain-containing protein 8A 1 SSFYSGGWQEGS(0.021)S(0.175)S(0.804)PR 136.63 1.0874000000000001e-05 4750000.0 34693.0 21736.0 31364.0 29086.0 31439.0 29354.0 26099.0 24571.0 29702.0 22931.0 True False 34198.271458083 21685.67162745585 28785.37298854116 31225.08146805163 29589.819831452154 28098.597847516136 27450.27851661225 25712.658360845544 26356.647984074036 26894.592796363122 1.2715668059011302 0.8063208761572452 1.0703033582435844 1.161017075234324 1.100214457809285 1.0447675508705165 1.020661614937121 0.9560530830688982 0.979998030966216 1.0 14.715028525193201 -7.39100549315726 2.3591840844255683 0.9768279712591654 1.069502024228893 0.13604323284407072 0.10999888382889618 0.6962257221462715 7.563241411517375 0.05625601118215127 0.03347800655365208 4.064381883147126e-08 7.39100549315726 0.09267405296972764 SSFYVNGLT(ph)LGGQK ddPTM_PC-9_AZD4547_30min_R2 2 SSFYVNGLTLGGQK 14 0 P07737;K7EJ44;I3L3D5 P07737 PFN1 Profilin-1 1 SSFY(0.05)VNGLT(0.949)LGGQK;S(0.062)S(0.034)FY(0.001)VNGLT(0.904)LGGQK 120.63 0.00020526 26651000.0 91813.0 98656.0 101076.0 147316.0 119790.0 114477.0 83750.0 114292.0 94139.0 109002.0 True False 121007.62417096394 130544.62267676998 99735.66619811492 113354.57220951152 103159.22622591261 107318.73509313488 91203.58775475205 96630.79756888292 99114.99535142233 105185.87315762641 1.150417071593139 1.2410851263376612 0.9481849910458596 1.0776596591031182 0.9807327080065518 1.0202770759179065 0.8670706913092674 0.9186670668605539 0.942284285674878 1.0 16.68258143292656 -5.207839190843919 0.6501600788973844 0.9357432004066902 1.2908234353804946 0.6035972596060042 0.06772843967470524 1.353076248433435 0.6250517839404504 0.03330106620268416 0.3296107026451931 6.196704821839857e-06 5.207839190843919 0.35508023497380437 SSFYVNGLT(ph)LGGQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSFYVNGLTLGGQK 14 0 P07737;K7EJ44;I3L3D5 P07737 PFN1 Profilin-1 1 S(0.03)S(0.16)FYVNGLT(0.81)LGGQK;SSFYVNGLT(1)LGGQK 120.59 0.00020669 15148600.0 61588.0 54936.0 51264.0 65157.0 77497.0 63681.0 68988.0 62022.0 58320.0 49600.0 True False 72013.63198155274 60389.683020624216 52486.32817980266 61506.46453184412 62312.01916686935 60341.45625600646 62452.95721013267 60393.988217741025 59172.819669399774 58592.08736661605 1.2290675280257017 1.0306798363874707 0.8957920862486244 1.0497401150259855 1.0634886375864603 1.0298567429155485 1.0658940484464874 1.030753313836565 1.0099114458774958 1.0 15.838418227000398 -4.764288286680651 6.230839169905222 1.0202818432803344 1.2355425547852177 0.6529360359301382 0.045874901141161176 0.08041089532721213 13.242705022820111 0.012022657439635539 0.07384472925978346 1.7207259699575043e-05 4.764288286680651 0.21526071150488324 SSFYVNGLTLGGQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSFYVNGLTLGGQK 14 0 P07737;K7EJ44;I3L3D5 P07737 PFN1 Profilin-1 0 ; 277.06 4.621199999999999e-69 19066900.0 89083.0 95317.0 91699.0 113818.0 120624.0 98524.0 105682.0 94614.0 89613.0 90386.0 False True 104162.9924305493 104779.44183189231 93885.45193039431 107441.14646293459 96988.59310662931 93357.22799841057 95671.0358885785 92130.48275181955 90923.4205938601 106772.26630481788 0.9755622507176207 0.9813357481123762 0.8793056022840823 1.006264549599492 0.9083687783655567 0.8743584006345851 0.896028895888122 0.8628690383774532 0.8515640225738784 1.0 16.704177435503077 -6.497544841151499 15.282276681316493 0.8886705592341447 0.9564194355596456 0.26838425846833736 0.04910620106084182 7.2617374763656 4379.732658661773 0.014616719259362157 0.016353189287495053 3.1802053133755973e-07 6.497544841151499 0.06774887632550086 SSFYVNGLTLGGQK ddPTM_PC-9_Lapatinib_30min_R1 2 SSFYVNGLTLGGQK 14 0 P07737;K7EJ44;I3L3D5 P07737 PFN1 Profilin-1 0 ; 198.97 3.1809e-07 66808000.0 415130.0 378050.0 400080.0 377660.0 417390.0 388730.0 433620.0 350840.0 399590.0 434750.0 False True 409210.1700744816 377174.64845232246 367186.9667534599 405434.3762368274 392839.94082031294 372104.9240738894 456070.7218810447 367141.3072043898 354583.9663307568 509895.95823203766 0.8025366027480116 0.7397090374281455 0.7201213518667755 0.7951315747678999 0.770431564475245 0.7297663730540027 0.8944387860268176 0.7200318050713305 0.6954045440175792 1.0 18.959843376706665 -11.423692541492137 2.6817273597689613 1.1279645014195792 0.7638925118038713 0.6287121176927064 0.05462055123334564 16638188.898709526 9367362.06819572 13418457.99306554 0.013647947034945136 3.769705806264889e-12 11.423692541492137 -0.36407198961570786 SSGDPEQIKEDS(ph)LSEESADAR ddPTM_PC-9_Lapatinib_30min_R1 1 SSGDPEQIKEDSLSEESADAR 21 1 Q9BVS4;Q9BVS4-2 Q9BVS4 RIOK2 Serine/threonine-protein kinase RIO2 1 SSGDPEQIKEDS(0.81)LS(0.155)EES(0.035)ADAR 51.475 0.016937999999999998 7932600.0 45478.0 49222.0 48233.0 43031.0 55943.0 45677.0 50455.0 54604.0 47170.0 49242.0 True False 44829.47538035623 49108.02948319066 44267.46892476426 46195.64328720792 52652.54272816977 43723.50118828757 53067.31302178895 57141.101181702375 41857.21787787932 57753.41408915939 0.7762220829256732 0.8503052201793293 0.7664909446985142 0.7998772715997594 0.9116784446177515 0.7570721467788463 0.9188601896307624 0.9893978058766927 0.7247574630524939 1.0 15.817618613418604 -14.522878737830704 0.08444931715090087 1.5167738621490288 0.6927551638173183 0.2978804657750391 0.07937127740923815 288.7115945277302 1.7059636942600809 27.485526457026427 2.244706493151326 3.000000051460249e-15 14.522878737830704 -0.8240186983317105 SSGDPEQIKEDSLS(ph)EESADAR ddPTM_PC-9_Lapatinib_30min_R1 1 SSGDPEQIKEDSLSEESADAR 21 1 Q9BVS4;Q9BVS4-2 Q9BVS4 RIOK2 Serine/threonine-protein kinase RIO2 1 SSGDPEQIKEDS(0.371)LS(0.542)EES(0.087)ADAR 50.158 0.020822 10656000.0 34022.0 33905.0 28864.0 30513.0 35810.0 28618.0 33665.0 31510.0 30456.0 29904.0 True False 33536.84004112932 33826.495055616986 26490.913338262064 32757.02780838409 33703.72620516881 27394.07485181634 35408.00897588991 32974.06963291045 27025.724564102027 35072.86655542468 0.9562047056556376 0.9644633694871193 0.7553107555779396 0.9339706452741484 0.9609629755214829 0.7810617591957086 1.0095556039006852 0.94015895680504 0.7705593302843958 1.0 15.098067728483151 SSGEIVYCGQVFEK ddPTM_PC-9_Lapatinib_30min_R1 2 SSGEIVYCGQVFEK 14 0 M0R117;Q02543;M0R3D6;M0R1A7;M0R0P7 M0R117 RPL18A 60S ribosomal protein L18a 0 ; 182.02 0.00010829 11695700.0 55372.0 47205.0 57396.0 53385.0 58401.0 50279.0 53728.0 52275.0 47207.0 51622.0 False True 54582.38512601884 47095.69972276654 52677.12243496712 57311.11098713938 54965.968000783665 48128.68437607353 56509.77294687696 54703.8873392699 41890.05054825206 60544.79391800875 0.9015207021752465 0.7778653898226939 0.8700520561074793 0.9465902396951172 0.9078562241903066 0.7949268840728169 0.9333547823022387 0.9035275173840918 0.6918852611007413 1.0 15.885715291383535 -5.501704147823031 24.54806130824582 0.8804127092064956 0.8357594595870061 0.03687863198993879 0.08561400525914165 2172.90537451102 2519080.018243348 0.021806207818780416 0.04462408096653763 3.1498933689054526e-06 5.501704147823031 -0.044653249619489466 SSGEIVYCGQVFEKS(ph)PLR ddPTM_PC-9_AZD4547_30min_R2 4 SSGEIVYCGQVFEKSPLR 18 1 M0R117;Q02543;M0R3D6;M0R1A7;M0R0P7 M0R117 RPL18A 60S ribosomal protein L18a 1 SSGEIVYCGQVFEKS(1)PLR;SSGEIVY(0.001)CGQVFEKS(0.999)PLR;SSGEIVYCGQVFEKS(1)PLR;SSGEIVYCGQVFEKS(1)PLR 122.97 0.00025183 134147200.0 281023.0 256227.0 348173.0 403534.0 399461.0 413500.0 393549.0 396163.0 378338.0 369444.0 True False 370382.46835847676 339047.3669579216 343555.9985278029 310505.4708381507 344002.7353487702 387643.779632689 428574.09859456605 334945.11127009237 398336.17428766453 356509.8780100022 1.0389122187186224 0.9510181564966604 0.9636647389561647 0.8709589551104646 0.9649178229477247 1.0873297026059214 1.2021380753510063 0.939511446750699 1.1173215634616689 1.0 18.44358252518343 -6.729426979784157 6.869195939538319 1.0738415067471518 0.9524079665677604 0.353218129402292 0.07509179181997581 0.1993280481616719 29.356314269302715 0.02503462076500077 0.024557273160830045 1.8645456477672992e-07 6.729426979784157 -0.12143354017939145 SSGEIVYCGQVFEKS(ph)PLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSGEIVYCGQVFEKSPLR 18 1 M0R117;Q02543;M0R3D6;M0R1A7;M0R0P7 M0R117 RPL18A 60S ribosomal protein L18a 1 SSGEIVYCGQVFEKS(1)PLR;SSGEIVYCGQVFEKS(1)PLR 102.61 0.00021384 67887000.0 177517.0 149446.0 173994.0 205519.0 231016.0 174622.0 204404.0 213624.0 168238.0 159402.0 True False 207567.1219794325 164282.01122579345 178142.67683591956 194004.43673158844 185750.0731622319 165464.51491553767 185041.37336319362 208016.5963533377 170698.1624749742 188300.32077446228 1.1023195346971668 0.8724467943024012 0.9460561517008296 1.0302926513012067 0.9864564882218925 0.8787266757432861 0.982692820713927 1.1047065427068001 0.9065208267989562 1.0 17.52267593205933 -7.531137742965551 24.9721687267743 1.0121081332584458 0.9643985960985603 0.032416996920361374 0.07736392640384511 556.3552242539457 1682187.6209396345 0.03507914992379238 0.02029494978646878 2.943487914687538e-08 7.531137742965551 -0.04770953715988557 SSGEIVYCGQVFEKS(ph)PLR ddPTM_PC-9_Lapatinib_30min_R1 3 SSGEIVYCGQVFEKSPLR 18 1 M0R117;Q02543;M0R3D6;M0R1A7;M0R0P7 M0R117 RPL18A 60S ribosomal protein L18a 1 SSGEIVYCGQVFEKS(1)PLR;SSGEIVYCGQVFEKS(1)PLR;S(0.02)S(0.02)GEIVY(0.295)CGQVFEKS(0.666)PLR 144.17 1.0207e-08 68478000.0 169269.0 177455.0 218445.0 213544.0 230192.0 199160.0 183829.0 165663.0 227483.0 187113.0 True False 166855.19301986674 177044.11385030273 200485.2953220845 229248.7381219017 216652.55913488453 190642.39106463574 193346.76613779488 173360.3077625152 201861.4690378126 219455.23273759914 0.7603153998126541 0.8067436426179592 0.9135589651753857 1.0446264382130845 0.9872289506713848 0.8687074292394992 0.8810305579223898 0.7899575034048094 0.9198298282510162 1.0 17.74356714497422 -5.183520344443283 3.5651559026516297 0.9213004732007426 0.7713336313362843 0.40952208061685014 0.06902212041916671 0.27097717710817903 6.565844772135497 0.020163510405209226 0.06260496486978175 6.553595849179576e-06 5.183520344443283 -0.1499668418644583 SSGGGYS(ph)GDR ddPTM_PC-9_AZD4547_30min_R2 2 SSGGGYSGDR 10 0 Q92804-2;Q92804;A0A075B7F4 Q92804-2 TAF15 TATA-binding protein-associated factor 2N 1 SSGGGYS(0.999)GDR;S(0.001)SGGGYS(0.999)GDR 109.39 0.0018908000000000002 50115000.0 112609.0 91623.0 125510.0 166500.0 158601.0 157433.0 141816.0 147392.0 130201.0 139040.0 True False 148416.319587293 121238.34296458073 123845.65539322294 128115.99739935705 136581.98880253732 147588.6896225224 154437.34926600475 124615.95313121506 137083.15904939047 134172.2519204821 1.1061625445122045 0.9036022070825293 0.9230347826808537 0.9548620938052503 1.0179600241299027 1.09999413075359 1.1510379162267685 0.928775893282833 1.0216952990446455 1.0 17.033726813963526 -6.402058594132177 4.442157871532241 1.0441747682956033 0.9640002394911288 0.15157926933318333 0.07486088187009905 0.40389775555524504 12.817527200440695 0.024688123321117535 0.027980500177359674 3.962245728319417e-07 6.402058594132177 -0.08017452880447451 SSGGGYS(ph)GDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGGGYSGDR 10 0 Q92804-2;Q92804;A0A075B7F4 Q92804-2 TAF15 TATA-binding protein-associated factor 2N 1 SSGGGYS(0.999)GDR 110.93 0.0016683 20972000.0 66343.0 77552.0 87108.0 98655.0 109250.0 103210.0 88083.0 89045.0 98433.0 79559.0 True False 77573.55956602194 85250.85003668729 89184.98507892982 93127.68019382544 87843.24675768698 97797.485909179 79739.14057430458 86707.66310097609 99872.39640805936 93982.41691130247 0.8254050291048944 0.9070936121715646 0.9489539427688872 0.9909053550060997 0.934677460365704 1.0405934335725486 0.8484474351150149 0.9225945230032544 1.062671079232998 1.0 16.52010324902411 -4.814341414303892 1.669599832029297 0.9646786122840121 0.7817594458656811 0.37430963700911946 0.05796789105937532 1.0283054130868656 2.9875302037369296 0.01613288858693832 0.3005495424277364 1.533411040009976e-05 4.814341414303892 -0.18291916641833095 SSGGGYS(ph)GDR ddPTM_PC-9_Lapatinib_30min_R1 2 SSGGGYSGDR 10 0 Q92804-2;Q92804;A0A075B7F4 Q92804-2 TAF15 TATA-binding protein-associated factor 2N 1 SSGGGYS(1)GDR;S(0.006)SGGGY(0.001)S(0.992)GDR 123.62 0.00044006 44676000.0 90165.0 116145.0 114782.0 93068.0 112374.0 117501.0 111270.0 105394.0 118218.0 90315.0 True False 88879.23056576388 115876.07338842758 105345.06703133321 99912.53118574698 105764.38225578454 112475.75613820925 117031.01615170848 110290.98999971346 104903.04394927151 105925.82741282722 0.8390704395385344 1.093935975943063 0.9945172919987625 0.9432310667383841 0.998475865981075 1.0618350489711528 1.1048392918905485 1.0412096151949213 0.9903443429375388 1.0 16.692694872430287 -6.615193761926261 5.003635280801495 1.04591917931082 0.9777501537606 0.20210762073042865 0.06571820217565817 0.35709640331248155 14.993159527255157 0.02175300600877036 0.02174819143479175 2.4255276964007103e-07 6.615193761926261 -0.06816902555021997 SSGGGYSGDR ddPTM_PC-9_Lapatinib_30min_R1 1 SSGGGYSGDR 10 0 Q92804-2;Q92804;A0A075B7F4 Q92804-2 TAF15 TATA-binding protein-associated factor 2N 0 93.598 0.030831 2300300.0 4676.3 6616.1 3670.5 5444.1 6105.9 5677.4 7747.0 9312.6 7389.0 6040.2 False True 4609.61510447161 6600.780826941974 3368.7256585397386 5844.477274985213 5746.762966661271 5434.590836665804 8148.101753637878 9745.29739331774 6556.773010380546 7084.240521939411 0.6506858554838653 0.9317556068995405 0.47552389675463785 0.8249970137074347 0.8112038190775619 0.7671381032074286 1.1501729406848569 1.375630508752098 0.9255435342821388 1.0 12.790397479518505 -7.250818500191204 6.407434969930648 1.1451491740686466 0.7456934997745432 0.5639941908813656 0.15808932989618932 0.10523626222239675 21.587522854768157 0.060844072188754116 0.04464801233089273 5.6128249750566054e-08 7.250818500191204 -0.39945567429410334 SSGGREDLES(ph)SGLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGGREDLESSGLQR 15 1 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 SSGGREDLES(0.5)S(0.5)GLQR 102.39 0.007186799999999999 6669400.0 21134.0 20893.0 26358.0 26713.0 32516.0 26826.0 26210.0 28847.0 25575.0 19016.0 True False 24711.568784473184 22967.11896297331 26986.474683271656 25216.357214714506 26144.723218059073 25419.197335525965 23727.19905603264 28089.796815922982 25948.98599185353 22463.450269426834 1.1000789499423462 1.0224216978026737 1.2013503873890976 1.1225504947935103 1.1638783403474986 1.1315802795495737 1.0562580000600261 1.2504667127718 1.1551647534381917 1.0 14.455291914781233 -5.252248122055878 24.97786824381509 1.141731455294521 1.0612503255343269 0.1517196023414068 0.06850438897258533 1063.986849189657 2891443.5396681447 0.016622165654292666 0.04260088104939018 5.594378909179271e-06 5.252248122055878 -0.08048112976019417 SSGGREDLESS(ph)GLQR ddPTM_PC-9_AZD4547_30min_R2 1 SSGGREDLESSGLQR 15 1 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 SSGGREDLES(0.128)S(0.872)GLQR 75.143 0.0072066000000000005 26556000.0 13879.0 16625.0 17976.0 27516.0 27152.0 25803.0 20278.0 24636.0 29983.0 27730.0 True False 18292.233298866304 21998.706130405633 17737.626494690263 21172.611317962193 23382.413477635648 24189.534330984938 22082.702716308777 20829.072278960924 31567.840168492334 26759.18114035512 0.6835871846347369 0.8220993764726872 0.6628613335234095 0.7912279231157824 0.8738090061497802 0.903971395989583 0.8252383583967816 0.7783897485393869 1.1797012772145463 1.0 14.707746348188607 -7.305249470688577 0.42875404593769023 1.041654962311918 0.709184676336785 0.5197830971865478 0.09978071632263154 0.9785530995897352 0.4178402191222667 0.10592522354541735 0.11155069702276703 4.951656723213745e-08 7.305249470688577 -0.33247028597513306 SSGGREDLESS(ph)GLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSGGREDLESSGLQR 15 1 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 SSGGREDLES(0.098)S(0.902)GLQR;SSGGREDLES(0.175)S(0.825)GLQR 94.461 0.0074085999999999996 21770200.0 44715.0 41379.0 59652.0 49135.0 64785.0 58376.0 49557.0 58315.0 51708.0 38739.0 True False 52284.3663384933 45486.8336557159 61074.32991146978 46382.125247819284 52090.8443130138 55314.659794925254 44862.60219839029 56784.293039849814 52464.131678074824 45762.074042244734 1.1425261514639304 0.9939854040209202 1.3346058103723557 1.0135494559316118 1.1382972778927531 1.2087445980674336 0.9803446005741762 1.2408592536131566 1.1464544117830666 1.0 15.481864819398556 -10.816651380260144 6.849726180259163 0.9999980720850951 1.1326025674009006 0.12179706991456474 0.10733874405448185 2.95961598345799e-06 3.052305101092225e-07 0.09733299315107949 0.023606375027371385 1.5252766426654955e-11 10.816651380260144 0.13260449531580554 SSGGREDLESS(ph)GLQR ddPTM_PC-9_Lapatinib_30min_R1 2 SSGGREDLESSGLQR 15 1 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 1 SSGGREDLES(0.276)S(0.724)GLQR;SSGGREDLES(0.131)S(0.869)GLQR 132.25 3.4009e-06 60546000.0 61276.0 61047.0 73010.0 54556.0 51241.0 63400.0 45667.0 39882.0 55625.0 36871.0 True False 60402.1930033578 60905.64942221652 67007.39962674996 58568.23023348088 48227.10512368207 60688.529792618494 48031.41380965289 41735.06331639909 49359.92674278223 43244.10322248073 1.3967729355515304 1.4084151337090123 1.5495153011270153 1.3543633898976035 1.115229627391392 1.4033943421231398 1.1107043557486342 0.965104146146401 1.1414256063731285 1.0 15.400215799427517 -6.8980848888748545 0.6709156962824392 1.0088401063746624 1.4581674748372824 0.686036636251592 0.10682751466466059 0.43898416799464657 0.42429666056357707 0.08710445972012705 0.07973422674266899 1.2644891613843336e-07 6.8980848888748545 0.44932736846262 SSGGREDLESSGLQR ddPTM_PC-9_AZD4547_30min_R2 1 SSGGREDLESSGLQR 15 1 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 0 109.6 0.00079566 12095000.0 14083.0 13661.0 28020.0 33895.0 24328.0 26160.0 16781.0 31570.0 14083.0 21439.0 False True 18561.101055402698 18076.651094584762 27648.436492057244 26081.031422529762 20950.477131847394 24524.211064549305 18274.476490895446 26691.581906429463 14827.398628985668 20688.427135523732 0.8971731361603492 0.8737566648334355 1.3364204205056558 1.2606580119252508 1.012666501643989 1.1854072281038328 0.8833187932163613 1.2901697036502993 0.7167001402211869 1.0 14.336536346156953 -8.26994517443646 24.99148224500839 0.8583500957639949 1.092364634781106 0.2195212529302799 0.17656166975347157 1079.4018077902413 3171427.806499553 0.1603971319837383 0.04411472593164037 5.370995958257709e-09 8.26994517443646 0.2340145390171111 SSGGREDLESSGLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSGGREDLESSGLQR 15 1 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 0 ; 93.478 0.004231100000000001 15543000.0 32667.0 34112.0 36043.0 51253.0 50953.0 39267.0 47298.0 45876.0 47657.0 27246.0 False True 38196.8778973401 37498.41392164581 36902.4018138387 48381.46057446793 40969.125419170974 37207.76939439719 42817.591032133976 44671.803609639916 48353.89346681385 32185.484120782687 1.1867734458800872 1.165072235077318 1.1465541942869277 1.5032074830040303 1.272906918703657 1.1560419366310395 1.330338573484 1.3879487859185131 1.502350975531574 1.0 14.974122548984289 SSGGREDLESSGLQR ddPTM_PC-9_Lapatinib_30min_R1 2 SSGGREDLESSGLQR 15 1 Q9UK76;Q9UK76-3;J3KT51;Q9UK76-2;J3KSH8 Q9UK76 HN1 Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed 0 ; 143.64 0.00013155 17891900.0 41142.0 33566.0 43075.0 31541.0 36779.0 34740.0 27608.0 26286.0 37338.0 28591.0 False True 40555.30753548124 33488.27998928891 39533.53977430846 33860.63035769158 34615.73153029612 33254.25118289536 29037.407153018525 27507.343521760864 33132.601253429275 33532.91625488721 1.2094178516182754 0.9986688820841284 1.1789472610675995 1.0097729079186963 1.032291115606478 0.9916898050299684 0.8659374249558895 0.8203087173413329 0.9880620284136608 1.0 15.03329033490041 -6.521837638116449 1.1379692922166342 0.9071376153049582 1.1135544413018656 0.524440119805627 0.07758844547526146 0.3619868837109573 0.9906786940100973 0.035322335972952285 0.04035659814085522 3.007200340523491e-07 6.521837638116449 0.20641682599690747 SSGGSGGGPLSHFYS(ph)GSPTSYFTSGLQAGLK ddPTM_PC-9_AZD4547_30min_R2 1 SSGGSGGGPLSHFYSGSPTSYFTSGLQAGLK 31 0 A0A087WZ13;Q8IY67-2;E9PAU2;K7EQG2 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 SSGGSGGGPLSHFY(0.014)S(0.445)GS(0.445)PT(0.057)S(0.008)Y(0.009)FT(0.015)S(0.006)GLQAGLK 66.633 5.7088999999999995e-05 3084200.0 4501.1 5025.2 11575.0 20312.0 17041.0 14746.0 6058.2 15958.0 7312.6 12030.0 True False 5932.35617130392 6649.497626858013 11421.507937029353 15629.382217271705 14675.151299071502 13823.930288908408 6597.368063711504 13492.057778359245 7699.129107031223 11608.833361647025 0.5110208740615652 0.5727963714964208 0.9838635443560977 1.3463353060874894 1.2641366140679478 1.190811329463955 0.5683058631462249 1.162223399892531 0.6632129919676006 1.0 13.502935374325205 -5.265760899497219 4.403009410481679 1.0409766706677581 0.5293786324608607 0.402942367779096 0.23433570876672108 0.18967105739952464 9.716417274907869 0.0641862288556277 0.1615206004270498 5.422993707437187e-06 5.265760899497219 -0.5115980382068974 SSGGSGGGPLSHFYS(ph)GSPTSYFTSGLQAGLK ddPTM_PC-9_Lapatinib_30min_R1 1 SSGGSGGGPLSHFYSGSPTSYFTSGLQAGLK 31 0 A0A087WZ13;Q8IY67-2;E9PAU2;K7EQG2 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 SSGGSGGGPLSHFY(0.023)S(0.522)GS(0.438)PT(0.008)S(0.003)YFT(0.004)S(0.001)GLQAGLK 96.287 1.1683e-12 2961200.0 5865.6 3236.1 10658.0 4719.4 6476.0 6425.1 5575.0 6677.4 8306.6 5900.5 True False 5781.955468380696 3228.607009275393 9781.740381069754 5066.480419456884 6095.094412305874 6150.3134506396345 5863.646221315501 6987.656381047171 7371.023235624176 6920.39356307796 0.8354951803939134 0.4665351731584781 1.4134659094040258 0.7321087122107955 0.8807438994257113 0.8887230754408396 0.8472995311422068 1.0097195076199244 1.0651161915054137 1.0 12.756638370985847 -5.2147490806425445 24.999999196670366 0.9596481472174521 0.6510152808430925 0.3172866892479559 0.19103098469719512 499.70509312545266 267561.959736333 0.046413951207117804 0.12279907976785183 6.098891669658201e-06 5.2147490806425445 -0.3086328663743596 SSGHS(ph)SSELS(ph)PDAVEK ddPTM_PC-9_AZD4547_30min_R2 1 SSGHSSSELSPDAVEK 16 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 SSGHS(0.966)S(0.033)S(0.019)ELS(0.981)PDAVEK 129.32 0.00021573 3825500.0 4613.9 7595.3 29785.0 62392.0 44772.0 37324.0 16010.0 44452.0 23890.0 36334.0 True False 6081.024224918169 10050.332190813231 29390.031438826714 48008.488346790844 38556.18062097465 34990.124379710935 17434.858984520342 37582.96480534061 25152.776627598367 35061.95771920889 0.17343652837692647 0.28664492357502047 0.8382313296420759 1.3692472260466255 1.0996585224860798 0.9979512456185924 0.49725857078906227 1.0719014923901575 0.7173808384869016 1.0 15.097618932205409 -5.274783247289602 3.804654900157894 0.9642103331855043 0.2047337809601056 0.6369536184098151 0.2191383475635861 0.1382277028417388 4.531048512034309 0.061432075905899323 0.15910349841086185 5.311494703069854e-06 5.274783247289602 -0.7594765522253987 SSGHS(ph)SSELS(ph)PDAVEK ddPTM_PC-9_Lapatinib_30min_R1 1 SSGHSSSELSPDAVEK 16 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 S(0.001)S(0.001)GHS(0.813)S(0.165)S(0.029)ELS(0.991)PDAVEK 113.29 0.0030474 3619600.0 15678.0 7946.9 47028.0 13113.0 29748.0 41447.0 17686.0 27319.0 50448.0 17462.0 True False 15454.42884500692 7928.499441306076 43161.5393733297 14077.37376368566 27998.281126818274 39674.40842767599 18601.69454173739 28588.340472912758 44766.014999009065 20480.283433347562 0.7546003401419161 0.38712840411164856 2.1074678733718493 0.6873622530420553 1.3670846508515275 1.9372001640892864 0.9082732962302997 1.3958957436283834 2.1858103255601247 1.0 14.321948060954522 -5.238750318431722 24.968825567099696 1.4308250021969509 0.5708642131071385 0.34185494531705896 0.48666956777440684 874.492476600836 962356.8962306414 0.11931809639529381 0.31521267654845664 5.770981492991025e-06 5.238750318431722 -0.8599607890898123 SSGHSSS(ph)ELSPDAVEK ddPTM_PC-9_Lapatinib_30min_R1 1 SSGHSSSELSPDAVEK 16 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SSGHS(0.004)S(0.087)S(0.586)ELS(0.323)PDAVEK 86.777 0.0044027 2964200.0 13451.0 10658.0 21592.0 10471.0 16851.0 17452.0 11438.0 12118.0 23849.0 8717.2 True False 13259.1862733887 10633.322055825574 19816.789107530305 11241.072270232024 15859.857310340683 16705.618642599 12030.203673436168 12681.04651893395 21162.874478896414 10223.956405061124 1.2968742968059856 1.0400398470558623 1.9382701101620972 1.0994835878474012 1.5512446143148304 1.6339681020479788 1.1766681308892226 1.2403267401117344 2.0699300388663864 1.0 13.31966596931004 SSGHSSSELS(ph)PDAVEK ddPTM_PC-9_AZD4547_30min_R2 3 SSGHSSSELSPDAVEK 16 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SSGHSSS(0.013)ELS(0.987)PDAVEK;SSGHSS(0.005)S(0.082)ELS(0.912)PDAVEK;SSGHSSSELS(1)PDAVEK 178.14 7.4353e-06 46185200.0 10692.0 15345.199999999999 70987.0 204668.0 108146.0 69860.0 25506.0 110039.0 44247.1 76061.0 True False 14091.833592584377 20305.235808258698 70045.6659979181 157484.95468907867 93131.79463584226 65491.64315632321 27775.984588330815 93035.00099466549 46585.91137375505 73398.12754116667 0.19199173146046153 0.2766451473420781 0.9543249718275404 2.1456263254229526 1.2688579089924004 0.8922794811024441 0.37842906241378094 1.2675391608932411 0.6347016325127163 1.0 16.163455638509895 -5.282350123444245 4.712406824025996 1.097186366331761 0.2201781696913259 0.36493386977888265 0.4414043699384893 0.20308139872694375 12.356087558506186 0.12565289639547178 0.299056749605048 5.219752086433408e-06 5.282350123444245 -0.8770081966404351 SSGHSSSELS(ph)PDAVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGHSSSELSPDAVEK 16 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SSGHSS(0.001)S(0.018)ELS(0.98)PDAVEK 136.81 1.0702e-06 0.0 5318.3 5737.4 16039.0 15343.0 21925.0 19920.0 14709.0 11775.0 18561.0 9081.9 True False 6218.583148786963 6306.971154844355 16421.430588246218 14483.38145267714 17628.953639929412 18875.360132844162 13315.657036061952 11465.918726643773 18832.419511037875 10728.37657771916 0.5796387835324314 0.5878774956448451 1.5306538197354547 1.3500068111662324 1.6432079459758586 1.759386426837847 1.2411623454489928 1.06874685499541 1.7553838993822517 1.0 13.389144162962719 -5.257174590118926 24.67789148676494 1.4324341055358871 0.5837580036853981 0.6394136209059602 0.25058888881892966 176.18438868684686 1019465.9291859127 0.06418188086032116 0.15761754564525596 5.531277024178492e-06 5.257174590118926 -0.848676101850489 SSGHSSSELS(ph)PDAVEK ddPTM_PC-9_Lapatinib_30min_R1 2 SSGHSSSELSPDAVEK 16 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SSGHS(0.001)S(0.007)S(0.109)ELS(0.883)PDAVEK;SSGHSSSELS(1)PDAVEK 135.81 4.9254e-06 30801000.0 43869.6 23037.3 219421.0 47147.4 99281.0 159378.0 67590.0 76353.0 217964.0 58146.0 True False 43244.01145930065 22983.958547257495 201381.05236955412 50614.777075115795 93441.48677395598 152561.77446826396 71089.47947959002 79900.63912033055 193414.59905732644 68196.45862532513 0.6341093413205733 0.337025690344605 2.952954690447374 0.7421906957543939 1.3701809251903876 2.2370923291845144 1.042421863430758 1.1716244616059728 2.8361384587425023 1.0 16.05740920301686 -5.151536011271232 21.30505326564389 1.6307111685205875 0.4854017296192119 0.29121716125074415 0.7365729925670123 10.49127061996168 2021.8524106351983 0.17851971066452701 0.4723222370589845 7.0544634670828065e-06 5.151536011271232 -1.1453094389013756 SSGKT(ph)PETLVPTAPK ddPTM_PC-9_AZD4547_30min_R2 1 SSGKTPETLVPTAPK 15 1 Q14676;Q14676-2 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 S(0.153)S(0.153)GKT(0.694)PETLVPTAPK 97.073 0.025973000000000003 7337400.0 33629.0 33861.0 39741.0 38488.0 35951.0 36756.0 31726.0 45031.0 36377.0 38611.0 True False 44322.322473346394 44805.90606205505 39214.0083736919 29615.18623367237 30959.82420943132 34457.64150950208 34549.552538594166 38072.493659436965 38299.81395488261 37259.24064227374 1.1895659092702762 1.2025447993488891 1.052463971292005 0.7948413795656225 0.8309300907841046 0.9248079379912801 0.9272747362273077 1.021826881147989 1.027927925923113 1.0 15.18531065144603 -5.477253002962638 4.154617745020598 0.9278026338578019 1.1895019981997434 0.677867049784016 0.07235286965583484 0.13300675030735398 4.853845366529535 0.021892128653659308 0.04607777450981844 3.3323222815638504e-06 5.477253002962638 0.2616993643419415 SSGKT(ph)PETLVPTAPK ddPTM_PC-9_Lapatinib_30min_R1 1 SSGKTPETLVPTAPK 15 1 Q14676;Q14676-2 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 S(0.019)S(0.06)GKT(0.908)PET(0.013)LVPT(0.001)APK 144.08 1.3948e-06 0.0 19282.0 20639.0 18195.0 13298.0 21151.0 19937.0 17283.0 15446.0 20017.0 12693.0 True False 19007.03514411427 20591.211663556373 16699.077334731104 14275.979280827563 19906.93976446595 19084.340985416948 18177.829173631526 16163.677548395268 17762.474671645334 14886.968137640628 1.2767566215216346 1.3831702649710773 1.1217245298261027 0.9589581403571206 1.337205774904071 1.2819494748002829 1.2210564975732159 1.0857602030816853 1.1931559540813548 1.0 13.8617623458155 -14.52287874304006 0.11785850325488195 0.3308833148318432 1.308223473856311 0.24967220974031357 0.11646831008172812 254.3724638836032 1.9471643719253109 40.58203640375152 1.2878024924463343 3.0000000154752885e-15 14.52287874304006 0.9773401590244678 SSGNS(ph)PTPVSR ddPTM_PC-9_AZD4547_30min_R2 2 SSGNSPTPVSR 11 0 H0YBT1;O95429-2;O95429 H0YBT1 BAG4 BAG family molecular chaperone regulator 4 1 S(0.029)S(0.124)GNS(0.818)PT(0.022)PVS(0.007)R;S(0.181)S(0.003)GNS(0.795)PT(0.022)PVSR 113.52 0.0015527000000000002 36847200.0 40189.0 28774.0 47669.0 75641.0 55503.0 45700.0 40663.0 64127.0 40519.0 56173.0 True False 52968.26601686994 38074.632793761906 47036.87791362869 58203.13609180042 47797.36650151783 42842.371775607906 44281.92822533111 54217.645641862626 42660.751618822 54206.40036773051 0.9771588900487544 0.7024010547733774 0.867736606646733 1.0737318046753976 0.8817661046899541 0.7903563321853097 0.8169132782277956 1.0002074528848224 0.7870058024405967 1.0 15.726175585992591 -10.763181619321585 4.693804773828167 1.0000333666521428 0.877204253346873 0.10618549120970988 0.10664132576851369 3.7441193925946796e-05 6.059893539396383e-06 0.10382324329286977 0.025173998035570275 1.7251163079296246e-11 10.763181619321585 -0.1228291133052698 SSGNS(ph)PTPVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSGNSPTPVSR 11 0 H0YBT1;O95429-2;O95429 H0YBT1 BAG4 BAG family molecular chaperone regulator 4 1 S(0.406)S(0.056)GNS(0.519)PT(0.016)PVS(0.003)R;S(0.05)S(0.01)GNS(0.915)PT(0.025)PVSR;S(0.004)S(0.018)GNS(0.953)PT(0.025)PVSR 127.78 0.0003432 54912700.0 61117.5 77392.0 89352.0 104143.0 108870.0 96075.0 91082.0 85828.0 79058.0 75858.0 True False 71463.48562435135 85074.96629409038 91482.49054934701 98308.20534616159 87537.70502983444 91036.65786962856 82454.05358342461 83575.10594228296 80214.07368695836 89610.45490840248 0.7974904903384266 0.949386613214405 1.020890817292001 1.097061781983472 0.9768693298043544 1.0159155866654612 0.9201387680456152 0.9326490533689545 0.8951419091550327 1.0 16.451379441794217 -10.392346673385838 14.858219479647 0.999999999998242 0.9626336764699245 0.022338974041259285 0.07695077382262734 0.0 0.0 0.07898511152155403 0.01915670339144458 4.05184969459164e-11 10.392346673385838 -0.03736632352831748 SSGNS(ph)PTPVSR ddPTM_PC-9_Lapatinib_30min_R1 2 SSGNSPTPVSR 11 0 H0YBT1;O95429-2;O95429 H0YBT1 BAG4 BAG family molecular chaperone regulator 4 1 S(0.073)S(0.224)GNS(0.646)PT(0.054)PVS(0.002)R;S(0.322)S(0.152)GNS(0.496)PT(0.031)PVSR 99.834 0.0043978 30902600.0 40549.0 32059.0 37933.0 34681.0 31825.0 33768.0 33156.0 33208.0 34412.0 27609.0 True False 39970.763824224094 31984.769355199096 34814.29516561445 37231.556432424484 29953.11607035737 32323.8213570527 34872.65544644606 34750.96491176421 30536.15818557522 32381.17886331997 1.2343826020954811 0.9877580272851058 1.0751398308432376 1.1497900243094243 0.9250162323239872 0.9982286776368033 1.076942121027852 1.0731840572712636 0.9430218187690903 1.0 14.982867888639799 -4.75398111120193 24.99834284151095 1.0307982262489832 1.2343829620851046 0.4769161581781385 0.06542732526834369 247.92656630915585 830921.793378725 0.016450018734088568 0.16751788458338782 1.7620526818166413e-05 4.75398111120193 0.20358473583612136 SSGNS(ph)SSSGSGSGSTSAGSSS(ph)PGAR ddPTM_PC-9_AZD4547_30min_R2 1 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 2 S(0.003)S(0.004)GNS(0.53)S(0.135)S(0.061)S(0.146)GS(0.032)GS(0.019)GS(0.03)T(0.039)SAGS(0.003)S(0.058)S(0.939)PGAR 165.34 3.6764000000000002e-09 1040700.0 2849.1 3021.1 5171.6 3076.1 3091.5 2068.7 2753.1 4304.5 2953.2 2938.1 True False 3755.0545350385464 3997.6114941695355 5103.0212049365855 2366.952670271242 2662.298588174374 1939.343861973743 2998.1205665386015 3639.3384325697057 3109.3001229227066 2835.2380132880403 1.3244230351877195 1.4099738630174066 1.7998563722057976 0.8348338514008122 0.9390035600880268 0.6840144823413523 1.0574493402272303 1.283609494339823 1.096662822786026 1.0 11.46925413664681 -5.771693407886089 24.99997702727477 0.9854498676243515 1.5012733990932086 0.6234841544360694 0.18738537523793686 141.3337377049607 344580.91479344317 0.057314881091988894 0.08609251374094362 1.691634727242572e-06 5.771693407886089 0.5158235314688571 SSGNS(ph)SSSGSGSGSTSAGSSSPGAR ddPTM_PC-9_AZD4547_30min_R2 1 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNS(0.243)S(0.243)S(0.243)S(0.243)GS(0.021)GS(0.008)GS(0.001)TSAGSSSPGAR 377.46 0.0 11976000.0 15976.0 16528.0 28884.0 25571.0 21473.0 13630.0 19760.0 18053.0 16387.0 12990.0 True False 21056.035678556662 21870.352777344036 28500.979287529655 19676.00101801176 18491.844600960165 12777.713945329018 21518.60171980775 15263.323666669969 17253.18336527644 12535.224053848284 1.6797494474853452 1.7447117565186152 2.2736713093516605 1.5696569070874544 1.4751905926470625 1.0193446794759358 1.7166507457201445 1.217634690939901 1.3763761454251593 1.0 13.61370016259701 -6.117012459607817 2.92836133187926 1.3143658281269213 1.8854093131843486 0.5318906045760874 0.2484521334453453 0.21298392472592473 3.511101457959513 0.07522336470784434 0.1032841607039385 7.638138699725722e-07 6.117012459607817 0.5710434850574273 SSGNS(ph)SSSGSGSGSTSAGSSSPGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 S(0.008)S(0.025)GNS(0.428)S(0.428)S(0.054)S(0.054)GS(0.003)GSGSTSAGSSSPGAR 265.86 2.5131999999999994e-96 3282600.0 4407.6 7337.7 5643.0 5191.0 8242.4 5813.9 5746.0 3918.4 4884.0 3450.5 True False 5153.719625931863 8066.138362830098 5777.550521196676 4900.165099449071 6627.3608885634785 5509.0088492139885 5201.697282562516 3815.5461518879797 4955.419260379775 4076.048335857028 1.264391194921452 1.9789113617402958 1.4174391580128036 1.202185228360096 1.625927943558111 1.3515563102505914 1.2761618248741424 0.9360895253185766 1.2157410442822558 1.0 11.992955444479788 -7.343129948731435 1.7896198595299841 1.0552842927687593 1.5037972990424342 0.4390486840236547 0.21412200731672767 0.34482185327148035 2.15036118766333 0.12046677198879878 0.06985552455342918 4.5380580946116234e-08 7.343129948731435 0.44851300627367485 SSGNSS(ph)SSGSGSGSTSAGSSS(ph)PGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 2 SSGNS(0.126)S(0.6)S(0.243)S(0.029)GS(0.002)GSGSTSAGSS(0.018)S(0.982)PGAR 209.17 5.678999999999999e-85 0.0 2374.7 4611.7 2637.5 2285.4 2913.4 1143.8 1885.6 936.57 1068.4 2065.8 True False 2776.689807537072 5069.519098336475 2700.38800277445 2157.3564473667698 2342.540184016893 1083.8171144551782 1706.9823174381952 911.9860298779416 1084.0233287857798 2440.313187136197 1.1378415779474707 2.0774051154826374 1.1065743598031614 0.8840490059796431 0.9599342397382835 0.4441303354702107 0.6994931332733589 0.3737167977804492 0.44421483869368567 1.0 11.252850598242507 -5.80711422267483 1.2755497286294695 0.586376696824272 1.622514345127493 0.5958138545674088 0.300254957518203 0.29319701022298117 0.9532299130099854 0.101435015347666 0.242102212232918 1.5591423828684773e-06 5.80711422267483 1.036137648303221 SSGNSS(ph)SSGSGSGSTSAGSSSPGAR ddPTM_PC-9_AZD4547_30min_R2 1 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNS(0.019)S(0.711)S(0.267)S(0.003)GSGSGSTSAGSSSPGAR 343.13 7.007699999999996e-246 11128000.0 22548.0 22288.0 46519.0 38074.0 27452.0 16295.0 31510.0 26247.0 20913.0 20100.0 True False 29717.794972464708 29492.160134404883 45902.127665025335 29296.627537436125 23640.763656012612 15276.071074037878 34314.3289570416 22191.129246058095 22018.418485264305 19396.30511796385 1.5321369091550139 1.5205040318266996 2.3665397809458653 1.5104231119927636 1.218828200125485 0.7875763441094755 1.769116785302653 1.144090542559357 1.1351862301275097 1.0 14.243494233215419 -6.053019721704813 4.715335504263135 1.2007317991983497 1.8012919712880733 0.43881121841657145 0.31942081044351694 0.2063039493652705 9.809772304647499 0.09608978457423681 0.1297225155802457 8.85075416843888e-07 6.053019721704813 0.6005601720897236 SSGNSS(ph)SSGSGSGSTSAGSSSPGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNS(0.078)S(0.837)S(0.078)S(0.007)GSGSGSTSAGSSSPGAR;S(0.019)S(0.019)GNS(0.063)S(0.61)S(0.258)S(0.021)GS(0.006)GS(0.003)GS(0.001)T(0.001)S(0.001)AGSSSPGAR 383.43 0.0 9331700.0 24806.0 27860.0 21154.0 24781.0 30876.0 19109.0 23123.0 15732.0 19445.0 16244.0 True False 29005.165859167297 30625.75667967436 21658.39158699176 23392.600911086003 24826.069445220557 18106.89040052807 20932.622043977208 15319.051669431845 19729.346338674168 19188.908612566745 1.5115589137868906 1.5960134730965192 1.1286932479738716 1.219068858130174 1.293771831763379 0.9436123109508133 1.0908709018640337 0.79832844997758 1.0281640679529576 1.0 14.227985038763123 -5.093961730750985 0.451353804485464 0.9306604477673237 1.920997095596555 0.7272736713538318 0.12374199070179358 1.946119689100026 0.38005109547270016 0.09224936775848701 1.003010211771525 8.054494128263776e-06 5.093961730750985 0.9903366478292313 SSGNSS(ph)SSGSGSGSTSAGSSSPGAR ddPTM_PC-9_Lapatinib_30min_R1 1 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNS(0.004)S(0.475)S(0.475)S(0.044)GS(0.001)GSGSTSAGSSSPGAR 383.43 0.0 10025000.0 40614.0 56211.0 23099.0 12222.0 15152.0 21393.0 21003.0 23876.0 25412.0 6677.4 True False 40034.83691230457 56080.84688309357 21199.88938471853 13120.8466513968 14260.789149978156 20478.07125951872 22090.43257153174 24985.3661236233 22549.832959776762 7831.579692923781 5.111974656719387 7.160860143422326 2.706974865348517 1.6753767650799918 1.8209339251011496 2.614807237168469 2.8206866861728463 3.190335424435355 2.879346676399354 1.0 12.935087624781714 -5.308559220095435 7.4832912057627965 2.3940246665444267 6.131501391491406 0.791518016618344 0.7794187176845362 0.09950446797746484 14.096409639906263 0.2027283937246745 0.429185068952886 4.914063677977606e-06 5.308559220095435 3.737476724946979 SSGNSSS(ph)SGSGSGSTSAGSSSPGAR ddPTM_PC-9_Lapatinib_30min_R1 1 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 S(0.008)S(0.008)GNS(0.054)S(0.359)S(0.533)S(0.037)GS(0.001)GSGSTSAGSSSPGAR 85.881 9.7909e-06 2568000.0 4494.4 6277.2 3257.9 915.1 2571.6 3131.4 3776.0 3534.8 3078.9 643.23 True False 4430.309031827982 6262.665529070019 2990.0480378576767 982.3995066841111 2420.343543960125 2997.4773216499266 3971.5028038901014 3699.039712421833 2732.1218597456577 754.4114484499005 5.872536850986287 8.301392485410982 3.9634181639228423 1.3022065196686248 3.2082539957913387 3.9732659516353896 5.264372395263092 4.903212590453526 3.6215275700804725 1.0 9.559207759340987 -8.648811713668788 3.5445104099643556 1.0008030350011323 4.539375610636981 0.2851382599204412 1.7177117298823825 0.9314496663414406 23.014184192760393 1.8633416073135196 0.49073820465347406 2.2448549591555862e-09 8.648811713668788 3.5385725756358486 SSGNSSSSGSGS(ph)GSTSAGSSSPGAR ddPTM_PC-9_Lapatinib_30min_R1 1 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 S(0.004)S(0.004)GNS(0.001)S(0.002)S(0.001)S(0.074)GS(0.102)GS(0.181)GS(0.181)T(0.181)S(0.135)AGS(0.077)S(0.029)S(0.029)PGAR 48.244 0.03392 798240.0 886.7 1296.8 636.84 0.0 0.0 598.06 382.18 701.3 671.3 0.0 True False 874.0554953991349 1293.7973392751542 584.4814734734904 0.0 0.0 572.4823679459529 401.9674103788981 733.8849582215207 595.6911248976129 0.0 0.0 SSGNSSSSGSGSGS(ph)TSAGSSSPGAR ddPTM_PC-9_Lapatinib_30min_R1 1 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNSS(0.001)S(0.001)S(0.182)GS(0.027)GS(0.057)GS(0.389)T(0.262)S(0.081)AGSSSPGAR 189.98 3.7969999999999996e-21 7414100.0 25125.0 31787.0 15311.0 9473.7 13207.0 16338.0 13753.0 12776.0 18861.0 5139.1 True False 24766.712892639287 31713.399154487466 14052.188682169166 10170.427501336762 12430.190225961038 15639.26182573818 14465.063046054174 13369.619601081056 16736.675564865007 6027.386587579689 4.109030096671535 5.261550539969936 2.331389977726956 1.6873693687234885 2.0622852118985135 2.594700306425535 2.399889709391057 2.2181453614790714 2.7767715446282097 1.0 12.557316884728678 -5.2726799954186765 22.993463430463255 2.1847869212476017 4.685290171223666 0.7808398990503708 0.5401529512340387 89.37393463772585 182821.68864309217 0.1338642485247328 0.2836170766910428 5.337280216045868e-06 5.2726799954186765 2.500503249976064 SSGNSSSSGSGSGST(ph)SAGSSSPGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNSSSSGS(0.065)GS(0.238)GS(0.077)T(0.468)S(0.151)AGSSSPGAR 170.8 2.2811000000000003e-10 7569800.0 14240.0 19560.0 15683.0 16579.0 26549.0 19698.0 16743.0 14325.0 14409.0 12996.0 True False 16650.550747179805 21501.78753246342 16056.942198108714 15650.132379843211 21346.914033591158 18665.00220365283 15156.981831177205 13948.983928592106 14619.70436585015 15352.071923720598 1.0845800377897472 1.400578869047692 1.04591369021005 1.0194149986792387 1.3904907519751706 1.2157969488674296 0.9872922629914235 0.9086059522063227 0.9522951975792361 1.0 13.90614575516828 -7.317244648181462 4.889332187910086 0.9498294746497445 1.1968114813790818 0.4586501904253423 0.12288537711056902 0.1994417905841848 10.283403961596663 0.053773203658224966 0.03612862366867309 4.8167638167734495e-08 7.317244648181462 0.24698200672933723 SSGNSSSSGSGSGSTS(ph)AGSS(ph)SPGARR ddPTM_PC-9_AZD4547_30min_R2 1 SSGNSSSSGSGSGSTSAGSSSPGARR 26 1 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 2 SSGNSS(0.001)S(0.002)S(0.001)GS(0.003)GS(0.033)GS(0.079)T(0.079)S(0.755)AGS(0.118)S(0.465)S(0.465)PGARR 69.876 0.00021217 1036400.0 2431.9 666.56 3679.7 4689.4 3643.1 678.88 2680.0 3443.8 2090.8 1095.9 True False 3205.19361333763 882.0124847087626 3630.9047737267306 3608.331280507776 3137.3184494834454 636.4295262806285 2918.5148081520656 2911.6398406513063 2201.3154195472016 1057.532874565999 3.030821727081543 0.834028431570727 3.433372957996051 3.4120275286842494 2.9666391702205663 0.6018059027638387 2.759739085510505 2.7532381363049487 2.081557436642903 1.0 10.046486796457577 SSGNSSSSGSGSGSTS(ph)AGSSS(ph)PGAR ddPTM_PC-9_AZD4547_30min_R2 1 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 2 S(0.001)S(0.001)GNS(0.033)S(0.168)S(0.099)S(0.207)GS(0.11)GS(0.005)GS(0.003)T(0.021)S(0.35)AGS(0.023)S(0.128)S(0.852)PGAR 107.75 0.0021184999999999997 0.0 1062.9 2239.1 978.39 2459.2 1005.7 2069.6 808.6 1239.9 0.0 758.96 True False 1400.880090306578 2962.845287013011 965.4159093313299 1892.269434261252 866.0759146456311 1940.1875848314698 880.5638335342385 1048.3019450675295 0.0 732.3890414094453 1.9127540297580856 4.045452784644574 1.3181736136759177 2.583694358151067 1.1825353270973473 2.649121539418009 1.202317052477517 1.431345754505182 0.0 1.0 9.516466394314497 -7.026842419921162 0.519938811813779 0.5839258617298343 2.7480336063284505 0.40487509041688075 0.8211795446395672 0.923643180037057 0.5340420722240398 0.7272353696557102 0.7456225224961617 9.400643430849137e-08 7.026842419921162 2.164107744598616 SSGNSSSSGSGSGSTS(ph)AGSSSPGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNSSSSGS(0.001)GS(0.026)GS(0.049)T(0.153)S(0.488)AGS(0.055)S(0.217)S(0.011)PGAR 117.6 6.818499999999999e-09 80136000.0 1020.7 2223.1 3968.0 2623.7 3778.7 811.57 4318.5 1204.3 1155.8 2019.7 True False 1193.48435025607 2443.7946760439368 4062.612168723799 2476.7025951501687 3038.290860624915 769.0098405126671 3909.42041676753 1172.6884010613246 1172.7013884412245 2385.855622063596 0.5002332660950333 1.0242843923347833 1.7027904501656004 1.0380773137512809 1.2734596479886777 0.322320358952621 1.6385821424458862 0.4915169175438337 0.49152236103328034 1.0 11.220291026926125 SSGNSSSSGSGSGSTS(ph)AGSSSPGARR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGNSSSSGSGSGSTSAGSSSPGARR 26 1 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNSS(0.001)S(0.002)S(0.001)GS(0.01)GS(0.063)GS(0.15)T(0.15)S(0.366)AGS(0.21)S(0.023)S(0.023)PGARR 49.208999999999996 0.01188 46328000.0 478.85 0.0 464.63 0.0 811.52 612.76 703.85 816.04 992.6 0.0 True False 559.9098472813939 0.0 475.70854131908754 0.0 652.5084815450634 580.6257868976702 637.1762325672861 794.6198146658504 1007.1148971852916 0.0 0.0 SSGNSSSSGSGSGSTSAGS(ph)SSPGAR ddPTM_PC-9_Lapatinib_30min_R1 2 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNSSSSGSGSGSTS(0.002)AGS(0.462)S(0.462)S(0.075)PGAR;SSGNSSSSGS(0.004)GS(0.012)GS(0.004)T(0.004)S(0.032)AGS(0.314)S(0.314)S(0.314)PGAR 141.36 1.5825e-06 4146700.0 3453.14 5708.2 661.24 596.33 1128.3 1664.06 2997.87 1123.1 2817.3 571.7 True False 3403.897590371679 5694.983013610765 606.8753996602144 640.1860974985639 1061.935612323149 1592.892032913323 3153.0850399094347 1175.2833260781256 2499.9860065157827 670.5175832576338 5.07652248854419 8.493413380663837 0.9050849892880943 0.954764071045374 1.5837550555555233 2.375615603060605 4.7024643628143625 1.7528001583018071 3.7284421302867012 1.0 9.389131354784384 -7.799566930844639 24.998332860665883 2.3054662842417377 3.3302918858438106 0.06060430202671152 2.2607767362470987 751.6098432106503 492783.5437156542 1.3538572032548732 0.6503923852404208 1.586474402249636e-08 7.799566930844639 1.024825601602073 SSGNSSSSGSGSGSTSAGS(ph)SSPGARR ddPTM_PC-9_AZD4547_30min_R2 3 SSGNSSSSGSGSGSTSAGSSSPGARR 26 1 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNSSSSGSGSGST(0.001)S(0.002)AGS(0.347)S(0.347)S(0.302)PGARR;SSGNSSSSGSGSGS(0.001)T(0.018)S(0.006)AGS(0.325)S(0.325)S(0.325)PGARR;SSGNSSSSGSGSGSTSAGS(0.442)S(0.115)S(0.442)PGARR 117.26 4.1512e-12 67306600.0 1167.0 534.84 2606.6 3347.7 2670.17 582.3 637.67 3113.2 751.0 1039.8 True False 1538.0817248920662 707.7165706337541 2572.034780877817 2575.9394864494134 2299.4629859891857 545.8886889482825 694.4213946695253 2632.1264742190733 790.6963268031133 1003.3969184904876 1.5328746745664314 0.7053206538629244 2.563327366748536 2.5672188532576543 2.291678341456841 0.5440406272818922 0.6920704876333628 2.6232156245594713 0.7880194888306399 1.0 9.970676697255728 -6.746157252443594 24.9980023923106 1.2035826380324932 1.9342847782439836 0.22281023659810417 0.7430781760127054 451.09646666467756 737887.4777514891 0.26308521839616417 0.2621361744117932 1.794083894517017e-07 6.746157252443594 0.7307021402114904 SSGNSSSSGSGSGSTSAGS(ph)SSPGARR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSGNSSSSGSGSGSTSAGSSSPGARR 26 1 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNSSSSGSGSGST(0.001)S(0.001)AGS(0.67)S(0.164)S(0.164)PGARR;SSGNSSSSGSGS(0.003)GS(0.021)T(0.071)S(0.056)AGS(0.283)S(0.283)S(0.283)PGARR 90.762 2.1800000000000002e-07 43610200.0 894.28 0.0 612.95 0.0 1520.6 1086.2 1050.7 720.29 0.0 526.06 True False 1045.6639411648848 0.0 627.56505262582 0.0 1222.6493457184345 1029.2377598541825 951.1700895907467 701.3831507103397 0.0 621.4305137113314 1.682672347258795 0.0 1.0098716409624815 0.0 1.9674755563843827 1.6562394944324972 1.5306137510212232 1.1286590137351191 0.0 1.0 9.279449272720168 -6.257996452087919 24.991332812810438 1.2582237720706377 0.6491074472175915 0.13399539717405673 0.6665833154762862 582.54301082445 4228528.799695596 0.20039961946523666 0.24824370043874333 5.520819494237562e-07 6.257996452087919 -0.6091163248530462 SSGNSSSSGSGSGSTSAGS(ph)SSPGARR ddPTM_PC-9_Lapatinib_30min_R1 3 SSGNSSSSGSGSGSTSAGSSSPGARR 26 1 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNSS(0.002)S(0.003)S(0.002)GS(0.003)GS(0.009)GS(0.035)T(0.15)S(0.316)AGS(0.365)S(0.046)S(0.069)PGARR;SSGNSSSSGSGSGST(0.003)S(0.049)AGS(0.316)S(0.316)S(0.316)PGARR;SSGNSSSSGSGSGS(0.002)T(0.007)S(0.013)AGS(0.429)S(0.316)S(0.234)PGARR 85.85799999999999 3.118e-05 882660.0 2935.48 0.0 822.03 0.0 0.0 0.0 0.0 0.0 405.98 0.0 True False 2893.6195168988993 0.0 754.445866527563 0.0 0.0 0.0 0.0 0.0 360.25425724107396 0.0 0.0 SSGNSSSSGSGSGSTSAGSS(ph)SPGAR ddPTM_PC-9_AZD4547_30min_R2 4 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNSSSSGSGSGS(0.001)T(0.001)S(0.037)AGS(0.042)S(0.697)S(0.22)PGAR;SSGNSSSSGSGSGS(0.002)T(0.007)S(0.028)AGS(0.086)S(0.439)S(0.439)PGAR;SSGNSSSSGSGSGSTSAGS(0.219)S(0.745)S(0.036)PGAR;SSGNSSSSGSGSGSTSAGS(0.223)S(0.553)S(0.223)PGAR 174.53 1.1695999999999999e-14 139282500.0 40019.72000000001 41912.02 60366.969999999994 53410.200000000004 59033.619999999995 44711.97 51227.509999999995 67248.06 43588.46 46784.27 True False 52745.15849811267 55459.26083077801 59566.46453472248 41097.30356936417 50837.820857455124 41916.12344769867 55786.6591491634 56856.41753368646 45892.45700799522 45146.36694732351 1.1683145746734256 1.2284324206084516 1.3194077079164364 0.9103125311792251 1.126066709127943 0.9284495360746554 1.2356843511739253 1.2593796882931056 1.0165260265912923 1.0 15.462322274277323 -5.738294076175595 24.99908016635453 1.082451446521497 1.237689629114823 0.31022972106418123 0.11521960418708689 326.8630840373482 353039.7857517524 0.03210928289047839 0.05557022151535355 1.826862763747205e-06 5.738294076175595 0.155238182593326 SSGNSSSSGSGSGSTSAGSS(ph)SPGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNSSSSGSGSGSTSAGS(0.001)S(0.499)S(0.499)PGAR 161.96 2.5535e-08 1577300.0 1394.2 1036.1 1068.2 620.13 2710.2 731.08 1676.4 714.72 730.78 868.87 True False 1630.210523294809 1138.9571606536467 1093.6699391710595 585.3861265885861 2179.155765333487 692.7408778072142 1517.5992559150354 695.9593573084364 741.4662750000676 1026.3892530288642 1.5882965633984127 1.1096737005893191 1.065550848222203 0.5703354013705011 2.123128003243234 0.6749299797936728 1.47858061786658 0.6780657097243248 0.7224026097428516 1.0 10.003362254314622 -7.776414656033914 24.910626747259442 0.7751754801960088 1.2067347609002688 0.17214719745340523 0.428859191064474 413.4501324371915 687743.3433376868 0.222738445889186 0.1076877816242464 1.673344435924663e-08 7.776414656033914 0.43155928070426 SSGNSSSSGSGSGSTSAGSS(ph)SPGAR ddPTM_PC-9_Lapatinib_30min_R1 3 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNSSSSGSGS(0.002)GS(0.005)T(0.005)S(0.096)AGS(0.032)S(0.43)S(0.43)PGAR;SSGNSSSSGSGS(0.002)GS(0.002)T(0.008)S(0.003)AGS(0.017)S(0.958)S(0.011)PGAR;SSGNSSSSGSGSGSTSAGS(0.078)S(0.461)S(0.461)PGAR 126.9 1.0817999999999999e-07 72096200.0 6378.9 10578.900000000001 4195.93 1217.4099999999999 2316.59 5238.3 4059.46 2976.7 6593.5 543.38 True False 6287.935716253004 10554.405207015678 3850.9568321581924 1306.942392560708 2180.3327307911754 5014.270120073714 4269.6389757096695 3115.008348977613 5850.870597366914 637.3025089916617 9.866485111131539 16.56106018429902 6.042588531859329 2.050741012503699 3.421189623497469 7.8679591706100105 6.6995483549328565 4.8878017974637675 9.180680312437723 1.0 9.315834530271687 -5.346021453809288 6.771776958864862 5.225584631026747 13.175470170503829 0.5697352328736977 2.8085208593771154 0.15774503582290794 10.598762030697698 0.7234757357197864 1.52478374712059 4.50794435097288e-06 5.346021453809288 7.949885539477082 SSGNSSSSGSGSGSTSAGSS(ph)SPGARR ddPTM_PC-9_AZD4547_30min_R2 2 SSGNSSSSGSGSGSTSAGSSSPGARR 26 1 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNSSSSGSGSGSTS(0.001)AGS(0.208)S(0.513)S(0.278)PGARR;SSGNSSSSGSGS(0.001)GS(0.002)T(0.012)S(0.123)AGS(0.138)S(0.362)S(0.362)PGARR 90.26799999999999 2.5244e-07 1602180.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SSGNSSSSGSGSGSTSAGSS(ph)SPGARR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSGNSSSSGSGSGSTSAGSSSPGARR 26 1 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNSSSSGSGSGSTS(0.006)AGS(0.226)S(0.541)S(0.226)PGARR;SSGNSSSSGSGSGS(0.001)T(0.008)S(0.015)AGS(0.206)S(0.433)S(0.337)PGARR 82.198 7.793500000000001e-06 1339260.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SSGNSSSSGSGSGSTSAGSS(ph)SPGARR ddPTM_PC-9_Lapatinib_30min_R1 4 SSGNSSSSGSGSGSTSAGSSSPGARR 26 1 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNSSSSGSGSGS(0.001)T(0.004)S(0.017)AGS(0.095)S(0.471)S(0.412)PGARR;SSGNSSSSGSGSGST(0.001)S(0.004)AGS(0.05)S(0.473)S(0.473)PGARR;SSGNSSSSGSGSGSTS(0.002)AGS(0.034)S(0.546)S(0.418)PGARR;SSGNSSSSGSGSGST(0.001)S(0.002)AGS(0.196)S(0.504)S(0.297)PGARR 113.28 2.7747e-11 110810130.0 12574.699999999999 2905.46 2651.78 1146.33 1136.3700000000001 510.47 1447.79 636.33 1207.3 0.0 True False 12395.382472082449 2898.7325858809304 2433.7608845668174 1230.6349322447793 1069.5309507893803 488.6383880636897 1522.7494821091248 665.8962148368747 1071.321160567389 0.0 0.0 SSGNSSSSGSGSGSTSAGSSS(ph)PGAR ddPTM_PC-9_AZD4547_30min_R2 9 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNSSSSGSGSGSTSAGS(0.032)S(0.253)S(0.714)PGAR;SSGNSSSSGSGSGSTSAGSS(0.041)S(0.959)PGAR;SSGNSSSSGSGSGSTSAGSS(0.088)S(0.912)PGAR;SSGNSSSSGSGSGSTS(0.001)AGS(0.096)S(0.249)S(0.654)PGAR;SSGNSSSSGSGSGSTSAGS(0.005)S(0.108)S(0.887)PGAR;SSGNSSSSGSGSGSTSAGS(0.049)S(0.152)S(0.798)PGAR;SSGNSSSSGSGSGSTSAGS(0.112)S(0.205)S(0.683)PGAR;SSGNSSSSGSGSGSTSAGSS(0.04)S(0.96)PGAR;SSGNSSSSGSGSGSTSAGSS(0.015)S(0.985)PGAR 239.27 3.160999999999999e-100 93637960.0 37554.560000000005 38709.9 66688.46 48901.680000000015 45644.57 37732.990000000005 51974.18000000001 51805.79 36391.399999999994 39337.75 True False 49496.128896626025 51222.11816164746 65804.12744693429 37628.15319942457 39307.60933812922 35373.5401703566 56599.78133267199 43800.39553412369 38314.97510948444 37960.54734597922 1.303883435755271 1.349351412001516 1.733487319010016 0.9912436945778165 1.035485842179056 0.9318501086919487 1.4910159439170214 1.15383993636654 1.0093367400705502 1.0 15.212213174006388 -5.780162643636637 24.997387475144645 1.102104500278026 1.4509519229083332 0.469942322039156 0.1817836484265522 224.30422832382146 299467.29620512686 0.05323896225519005 0.07911756278088942 1.6589655071558823e-06 5.780162643636637 0.3488474226303071 SSGNSSSSGSGSGSTSAGSSS(ph)PGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 10 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNSSSSGSGSGSTSAGS(0.001)S(0.235)S(0.764)PGAR;SSGNSSSSGSGSGSTS(0.001)AGS(0.031)S(0.248)S(0.719)PGAR;SSGNSSSSGSGSGSTSAGSS(0.041)S(0.959)PGAR;SSGNSSSSGSGSGSTSAGS(0.095)S(0.198)S(0.707)PGAR;SSGNSSSSGSGSGSTSAGSS(0.039)S(0.961)PGAR;SSGNSSSSGSGSGSTSAGS(0.001)S(0.248)S(0.751)PGAR;SSGNSSSSGSGSGSTSAGSS(0.002)S(0.998)PGAR;SSGNSSSSGSGSGS(0.001)T(0.001)S(0.002)AGS(0.229)S(0.169)S(0.597)PGAR;SSGNSSSSGSGSGSTSAGSS(0.216)S(0.784)PGAR;SSGNSSSSGSGSGSTSAGS(0.012)S(0.012)S(0.976)PGAR 270.46 7.581799999999998e-97 203108400.0 229372.66999999998 255958.56 249704.3 187652.92 332887.27 151708.05000000002 228924.86000000002 145753.34999999998 162061.14 153546.98 True False 268200.9327142643 281368.4342656084 255658.1975208313 177139.335271375 267660.3990947621 143752.21279124127 207239.43998834022 141927.4790009394 164430.9775829448 181383.83199677474 1.4786374825239843 1.5512321642350764 1.4094872442951656 0.9765993656729272 1.475657428494076 0.7925304654154478 1.1425463764158716 0.7824703968293221 0.9065360223830127 1.0 17.468686338585357 -5.934933508399337 0.600196320278714 0.8952722907273183 1.6280944068033343 0.5933498265658919 0.1822851569559354 0.8092790843823489 0.5245259967053838 0.1138863621456418 0.34907412490582657 1.1616264482194008e-06 5.934933508399337 0.732822116076016 SSGNSSSSGSGSGSTSAGSSS(ph)PGAR ddPTM_PC-9_Lapatinib_30min_R1 5 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNSSSSGSGSGSTSAGS(0.001)S(0.084)S(0.914)PGAR;SSGNSSSSGSGSGSTSAGSS(0.056)S(0.944)PGAR;SSGNSSSSGSGSGSTSAGSS(0.037)S(0.963)PGAR;SSGNSSSSGSGSGST(0.167)S(0.034)AGS(0.164)S(0.164)S(0.47)PGAR;SSGNSSSSGSGSGSTSAGSS(0.027)S(0.972)PGAR 273.84 1.2527999999999997e-110 153585600.0 131586.7 152797.00000000003 87703.2 53242.79 73543.43000000001 77018.79999999999 70831.94 68171.49 101739.5 25998.13 True False 129710.24952795434 152443.20793431962 80492.58144014241 57158.44238934078 69217.75003934655 73724.8854635918 74499.27126985582 71338.98629765963 90280.52614556935 30491.872130169315 4.2539286854616 4.999470261568132 2.639804505821121 1.8745468348198597 2.270039364715196 2.417853687332199 2.4432501537399745 2.3396066333059067 2.9608062686398275 1.0 14.896137110743112 -5.3364228280512505 4.84802964756852 2.269888054095306 4.624819002719921 0.7765564689425511 0.5135159545334185 0.08397426561855095 3.6279097756064655 0.12721406610003516 0.2803331539537241 4.608686554605784e-06 5.3364228280512505 2.354930948624615 SSGNSSSSGSGSGSTSAGSSS(ph)PGARR ddPTM_PC-9_AZD4547_30min_R2 2 SSGNSSSSGSGSGSTSAGSSSPGARR 26 1 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNSSSSGSGSGSTSAGS(0.022)S(0.338)S(0.639)PGARR;SSGNSSSSGSGSGST(0.001)S(0.003)AGS(0.012)S(0.099)S(0.885)PGARR 93.20700000000001 4.7503e-08 67489390.0 1325.6 400.0 3480.7 5271.4400000000005 4355.59 878.23 1086.4 2069.2 699.09 2397.7 True False 1747.1132258071298 529.2921775736698 3434.543643751021 4056.1909509361353 3750.891511456064 823.3141392667869 1183.0874953643288 1749.4526854857095 736.0424701794788 2313.7572528030805 0.75509789269835 0.2287587329796333 1.4844010276316262 1.7530754127392247 1.6211257714749108 0.35583427702683795 0.5113274065077643 0.7561090012214009 0.3181156836084576 1.0 11.176021797099 -6.776389854145752 24.982280793792768 0.5682246850697044 1.166311834409798 0.2922690922650687 0.45089505666684426 346.8673704711514 579612.6251146934 0.1770191137368979 0.15673433167113182 1.6734400007737886e-07 6.776389854145752 0.5980871493400937 SSGNSSSSGSGSGSTSAGSSS(ph)PGARR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGNSSSSGSGSGSTSAGSSSPGARR 26 1 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNSSS(0.001)SGS(0.001)GS(0.003)GS(0.006)T(0.006)S(0.018)AGS(0.199)S(0.199)S(0.567)PGARR 47.59 0.014941 1831200.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SSGNSSSSGSGSGSTSAGSSS(ph)PGARR ddPTM_PC-9_Lapatinib_30min_R1 2 SSGNSSSSGSGSGSTSAGSSSPGARR 26 1 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 SSGNSSSSGSGSGSTSAGS(0.031)S(0.27)S(0.698)PGARR;SSGNSSSSGSGSGST(0.001)S(0.005)AGS(0.221)S(0.221)S(0.551)PGARR 81.297 1.1484e-05 8023800.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SSGNSSSSGSGSGSTSAGSSSPGAR ddPTM_PC-9_Lapatinib_30min_R1 2 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 0 ; 139.39 5.8304999999999995e-06 873660.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 False True 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SSGPT(ph)SLFAVTVAPPGAR ddPTM_PC-9_AZD4547_30min_R2 1 SSGPTSLFAVTVAPPGAR 18 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;A0A1X7SBS1;A0A1W2PP22 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 1 S(0.036)S(0.003)GPT(0.919)S(0.041)LFAVTVAPPGAR 278.89 1.8355999999999996e-91 20508000.0 26348.0 30901.0 44078.0 61553.0 44546.0 55205.0 37209.0 46003.0 40899.0 58642.0 True False 34726.115927554514 40889.14394800989 43493.49691994644 47362.90683437008 38361.5568199307 51753.02262302923 40520.52891661573 38894.29339377495 43060.83764303665 56588.96142923561 0.6136552969076744 0.7225639579751201 0.7685862369878439 0.8369637052554375 0.6778982305215436 0.914542718507854 0.7160500545196712 0.6873123734990646 0.7609405890384495 1.0 15.788233039595315 -12.102768391672521 1.8838323131207055 4.12229269020282 0.7476310304725535 0.47655992956520365 0.0803320062766766 4858340.1965329405 217565.15747929522 64894911.27236355 0.020666307721214323 7.892809272471527e-13 12.102768391672521 -3.3746616597302665 SSGPT(ph)SLFAVTVAPPGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSGPTSLFAVTVAPPGAR 18 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;A0A1X7SBS1;A0A1W2PP22 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 1 S(0.011)SGPT(0.844)S(0.145)LFAVTVAPPGAR;S(0.022)S(0.007)GPT(0.486)S(0.486)LFAVTVAPPGAR 260.25 2.7964999999999995e-65 21601500.0 53445.0 46491.0 60018.0 52238.0 56121.0 43187.0 50369.0 49592.0 42917.0 39429.0 True False 62492.18291313379 51106.31923168486 61449.05673953248 49311.27421788104 45124.4929179694 40922.19769363158 45597.68368001936 48290.26254706737 43544.57993401286 46577.16558020775 1.3416914089699112 1.0972397868152308 1.319295753059828 1.0587006230116138 0.9688114842510803 0.878589265445144 0.9789707705914031 1.0367797598999362 0.9348911508800882 1.0 15.507335227604061 -5.94438828756113 4.247363741163418 0.9672162421106397 1.2361364776829167 0.7537226188583696 0.07285660087326874 0.10344178633863825 3.8805223627415386 0.020482499777547854 0.030746786174497363 1.1366106274605561e-06 5.94438828756113 0.26892023557227696 SSGPTS(ph)LFAVTVAPPGAR ddPTM_PC-9_AZD4547_30min_R2 2 SSGPTSLFAVTVAPPGAR 18 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;A0A1X7SBS1;A0A1W2PP22 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 1 SSGPT(0.164)S(0.836)LFAVTVAPPGAR;SSGPT(0.068)S(0.932)LFAVTVAPPGAR 132.59 4.006e-05 18658000.0 20152.6 14739.7 22328.0 28452.0 25733.7 22254.6 22437.0 27698.0 22366.6 25458.0 True False 26560.70759987991 19504.019774456545 22031.916131143964 21892.830979018054 22161.01995099561 20863.016343926563 24433.84953377159 23417.910536721025 23548.852813681093 24566.72316881211 1.08116607238849 0.793920281530149 0.8968194895082251 0.8911579630942148 0.9020747211060455 0.8492388749026379 0.9945913163050901 0.9532370424742066 0.9585671093317313 1.0 14.584417816273657 -7.273652705574755 24.8789348303218 0.9727019564364623 0.89668657467821 0.21013530608262798 0.06979076076858132 1116.2290956240206 2273785.2654396775 0.0275634480745165 0.01873953870739563 5.3253394310283925e-08 7.273652705574755 -0.07601538175825229 SSGPTS(ph)LFAVTVAPPGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSGPTSLFAVTVAPPGAR 18 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;A0A1X7SBS1;A0A1W2PP22 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 1 S(0.025)S(0.025)GPT(0.123)S(0.827)LFAVTVAPPGAR;SSGPT(0.166)S(0.834)LFAVTVAPPGAR 258.12 2.2097999999999997e-65 21476400.0 56555.0 49030.0 56166.0 63406.0 65199.0 55792.0 58590.0 55186.0 56916.0 44668.0 True False 66128.64448783382 53897.374372018465 57505.21045074115 59853.56738502554 52423.723984937664 52866.16930379724 53039.931045133606 53737.425974400285 57748.28882550675 52765.954808306546 1.2532445348155377 1.0214422266747991 1.0898165428760238 1.1343216966786176 0.9935141735876443 1.0018992264208004 1.0051922918446636 1.0184109464070725 1.0944232703700811 1.0 15.687319766118353 SSGPTS(ph)LFAVTVAPPGAR ddPTM_PC-9_Lapatinib_30min_R1 4 SSGPTSLFAVTVAPPGAR 18 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;A0A1X7SBS1;A0A1W2PP22 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 1 SSGPT(0.145)S(0.855)LFAVT(0.001)VAPPGAR;SSGPT(0.04)S(0.96)LFAVTVAPPGAR;SSGPT(0.006)S(0.994)LFAVTVAPPGAR;S(0.024)S(0.003)GPT(0.05)S(0.923)LFAVTVAPPGAR 232.62 1.31e-36 36365200.0 90655.0 76668.4 82491.0 71954.4 67586.6 73184.4 68060.6 59831.0 78899.0 47576.0 True False 89362.24307590908 76490.87903029256 75708.9084044685 77246.16660884189 63611.2890683681 70054.47381316884 71584.44484492652 62610.96668380404 70012.56377669708 55799.448208964815 1.601489726945938 1.3708178393420642 1.3568038902632913 1.3843535928807162 1.1399985324254196 1.25546893494036 1.282888041775038 1.1220714306946298 1.2547178515906678 1.0 15.767963235114197 -1.5228787452803376 0.186321987991161 1.0468810317909398 3.205866871442697 0.7555796524833199 0.07855723048435534 27.831049412573496 0.32107020416919047 0.1636619583635055 17.17711859452194 0.029999999999999995 1.5228787452803376 2.1589858396517574 SSGPTSLFAVTVAPPGAR ddPTM_PC-9_Lapatinib_30min_R1 1 SSGPTSLFAVTVAPPGAR 18 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;A0A1X7SBS1;A0A1W2PP22 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 75.89 0.025949 8817100.0 49104.0 71007.0 58976.0 47402.0 38182.0 45759.0 42695.0 36975.0 57186.0 28178.0 False True 48403.76795542927 70842.5876541571 54127.2209339435 50888.101208436485 35936.20982870024 43801.99423943893 44905.5381917606 38692.99348387385 50745.11048472349 33048.5297551751 1.464626968703492 2.1435927158927184 1.6378102546443134 1.539799246302867 1.0873769603343082 1.3253840507860999 1.3587756709427838 1.1707931871860313 1.5354725568927092 1.0 15.01229847088609 -5.883126475313245 2.45500444453361 1.2661596478178034 1.8061217478782283 0.5284106968742379 0.21301086629037216 0.2064311555510406 2.5264051605466014 0.0606142926148191 0.10097520075511804 1.3088007183259797e-06 5.883126475313245 0.5399621000604249 SSGPYGGGGQYFAKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGPYGGGGQYFAKPR 16 1 F8W6I7;P09651-2;P09651;P09651-3;H0YH80 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 0 147.39 3.6145999999999996e-10 0.0 38805.0 62538.0 33541.0 35383.0 41114.0 32367.0 43276.0 28840.0 28791.0 25598.0 False True 45373.92006631409 68746.35934075655 34340.74464495084 33400.60522323377 33058.00683931851 30669.61754115296 39176.583988892344 28082.980558505846 29212.01390777929 30238.714766343506 1.5005240935972737 2.273455068178793 1.135654901681635 1.1045643137058698 1.093234520539641 1.0142500360263016 1.2955770207699742 0.9287094631999026 0.9660468089831992 1.0 14.884109201660468 -5.34475780196442 7.19918247665644 1.0700609249718926 1.8837062882158155 0.7326539372969716 0.19820842915219683 0.10893674078627595 8.117740102377963 0.048218807453255345 0.10130944294927786 4.521080063933916e-06 5.34475780196442 0.8136453632439229 SSGPYGGGGQYFAKPR ddPTM_PC-9_Lapatinib_30min_R1 2 SSGPYGGGGQYFAKPR 16 1 F8W6I7;P09651-2;P09651;P09651-3;H0YH80 F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 0 ; 96.70700000000001 0.0029663 52959000.0 128807.0 184616.0 158463.0 189742.0 182667.0 176446.0 190608.0 207493.0 193483.0 172838.0 False True 126970.18855968902 184188.5329947734 145434.783824869 203696.2596407572 171922.88619713974 168899.81589571532 200476.74958789322 217133.88227043758 171690.90707368508 202712.81800784168 0.626355007085824 0.908618087424784 0.717442464932055 1.0048514032934883 0.8481105826790348 0.8331975133865568 0.9889692795851619 1.0711403669699764 0.8469662094433685 1.0 17.629077791123585 -3.350117351156309 0.35916047713298627 0.9757959530429908 6.115928228735346e-14 0.4438555284354361 0.09839018239880291 17.115152186911345 0.7823391262581162 0.08252002162538485 8.891456984713663 0.00044656290962610665 3.350117351156309 -0.9757959530429297 SSGQPS(ph)PESQTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSGQPSPESQTR 12 0 C9J6N8 C9J6N8 TFAP2A 1 S(0.018)S(0.102)GQPS(0.832)PES(0.013)QT(0.034)R;S(0.147)S(0.008)GQPS(0.837)PES(0.007)QT(0.001)R 137.73 6.7273e-05 27754000.0 24976.8 22652.0 26163.0 33461.0 33928.0 31837.0 29970.0 20338.1 24915.1 22301.9 True False 29204.878925713518 24900.740858147285 26786.82514373005 31586.288652025687 27280.051954185874 30167.411674164625 27131.02463599 19804.24642499819 25279.4362027617 26345.057928256738 1.1085524657127226 0.9451769256289875 1.0167685042362153 1.19894550006464 1.035490300627743 1.1450880752024528 1.02983355397713 0.7517252943200737 0.9595513614584961 1.0 14.685244731502891 -7.5460510566318595 22.38300164185882 0.8915383451480393 1.0717236804827817 0.42382570030452615 0.08899914928741703 63.678254209756226 61506.715332401975 0.041121038361800775 0.023745077839505094 2.8441267258858942e-08 7.5460510566318595 0.18018533533474235 SSGQPS(ph)PESQTR ddPTM_PC-9_Lapatinib_30min_R1 1 SSGQPSPESQTR 12 0 C9J6N8 C9J6N8 TFAP2A 1 S(0.017)S(0.002)GQPS(0.848)PES(0.054)QT(0.079)R 116.87 0.00065669 12809000.0 7728.6 5967.4 6525.7 5445.6 7485.4 6104.8 5171.1 5226.4 6534.9 3988.2 True False 7618.388746748343 5953.582851935966 5989.182135930465 5846.087589989067 7045.123488862627 5843.711934983863 5438.834255613375 5469.237623911243 5798.870746452273 4677.5550560575375 1.6287117212831863 1.2727980281548892 1.2804086887602406 1.249816949223987 1.506155118311015 1.2493090653024226 1.1627515209190245 1.169251362809393 1.239722606566139 1.0 12.191538919129478 -1.522878748961071 0.07206386917061974 0.7049384935709146 2.644876710343368 0.5638276572436316 0.11061363398975509 194.6094451675616 1.036970888220644 4.7349479920914845 38.124770984162694 0.02999999974574395 1.522878748961071 1.9399382167724535 SSGQPSPESQT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 SSGQPSPESQTR 12 0 C9J6N8 C9J6N8 TFAP2A 1 S(0.055)S(0.001)GQPS(0.071)PES(0.137)QT(0.736)R 101.97 0.0062421 15501000.0 6286.5 5545.3 7163.8 9667.2 10196.0 9438.6 8563.3 8635.8 6266.3 7984.7 True False 8285.476232676925 7337.709780748179 7068.80333125623 7438.576396751132 8780.461395770959 8848.40284991801 9325.417110689761 7301.33554094215 6597.523825095001 7705.158083353525 1.0753155409721102 0.9523113869137618 0.9174118499304905 0.9654021781618829 1.1395562947294429 1.1483739534214603 1.210282386137761 0.9475906220167233 0.856247691964751 1.0 12.91160884084804 -4.359636854129378 17.91962824944868 1.0225814315067194 45.47305418468637 0.02291726941513117 0.10853891843029871 704.2834397340564 77313.00151796 0.02913184063905719 12.904540855003248 4.368809881925101e-05 4.359636854129378 44.450472753179646 SSGRNS(ph)PSAASTSSNDSK ddPTM_PC-9_AZD4547_30min_R2 4 SSGRNSPSAASTSSNDSK 18 1 D6RA28;A0A590UJ84;B1AKN3;Q9P2R6-2;Q9P2R6 D6RA28 RERE Arginine-glutamic acid dipeptide repeats protein 1 S(0.004)S(0.004)GRNS(0.496)PS(0.496)AASTSSNDSK;SSGRNS(0.999)PS(0.001)AASTSSNDSK;S(0.003)S(0.003)GRNS(0.954)PS(0.04)AASTSSNDSK;S(0.079)S(0.213)GRNS(0.627)PS(0.08)AASTSSNDSK 132.9 2.7726999999999997e-05 87309400.0 28204.0 29815.3 32341.7 35067.8 37165.4 36925.9 30856.1 37648.5 31481.3 36678.1 True False 37172.2853203563 39452.51265503059 31912.82792630861 26983.460502109145 32005.625731501186 34616.9176356438 33602.23312381377 31830.789401463728 33145.33724765224 35394.01088294477 1.050242241358083 1.1146663424359593 0.9016448582742108 0.7623736284466026 0.9042667087759659 0.9780444988314272 0.9493762443296756 0.8993269936751349 0.9364673971896162 1.0 15.111217638149464 -5.266259062098462 24.832227283161522 0.9102817473306284 1.0824542983029866 0.5287160104720672 0.06248044052414259 258.141561675229 1330018.6156954756 0.01728787705230911 0.03793814819425726 5.416776764915105e-06 5.266259062098462 0.17217255097235817 SSGRNS(ph)PSAASTSSNDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 SSGRNSPSAASTSSNDSK 18 1 D6RA28;A0A590UJ84;B1AKN3;Q9P2R6-2;Q9P2R6 D6RA28 RERE Arginine-glutamic acid dipeptide repeats protein 1 S(0.008)S(0.008)GRNS(0.96)PS(0.023)AASTSSNDSK;S(0.003)S(0.011)GRNS(0.976)PS(0.011)AASTSSNDSK;S(0.012)S(0.012)GRNS(0.903)PS(0.072)AASTSSNDSK;S(0.002)S(0.002)GRNS(0.994)PS(0.002)AASTSSNDSK;SSGRNS(0.999)PSAASTSSNDSK;S(0.025)S(0.025)GRNS(0.906)PS(0.038)AAS(0.005)T(0.001)SSNDSK;S(0.099)S(0.099)GRNS(0.571)PS(0.231)AASTSSNDSK 123.6 2.1511999999999997e-05 77808880.0 36087.840000000004 39879.4 38786.50000000001 52846.50000000001 57333.899999999994 48820.2 51718.420000000006 47883.20999999999 43570.68 47245.380000000005 True False 42196.79854467031 43838.36327822704 39711.31725862038 49885.68193566467 46099.73386984485 46259.98276894972 46819.27684866458 46626.32647395469 44207.81876737179 55810.59339977774 0.756071490629203 0.7854846294897417 0.71153726989003 0.8938389452039643 0.8260032918773524 0.82887459084307 0.8388958797354595 0.8354386440574985 0.7921044388599503 1.0 15.768251365309961 -14.522878745280298 0.1484011818325674 1.6521519113589278 0.7514268989141193 0.6277376220524138 0.04562436716707835 92.66796491263766 0.8179670924049199 17.9425871932508 0.2446674469721981 3.0000000000002712e-15 14.522878745280298 -0.9007250124448085 SSGRNS(ph)PSAASTSSNDSK ddPTM_PC-9_Lapatinib_30min_R1 3 SSGRNSPSAASTSSNDSK 18 1 D6RA28;A0A590UJ84;B1AKN3;Q9P2R6-2;Q9P2R6 D6RA28 RERE Arginine-glutamic acid dipeptide repeats protein 1 S(0.049)S(0.049)GRNS(0.861)PS(0.042)AASTSSNDSK;S(0.001)S(0.001)GRNS(0.978)PS(0.02)AASTSSNDSK;SSGRNS(0.967)PS(0.012)AAS(0.02)TSSNDSK 107.63 0.00016459 33454490.0 12824.6 15984.6 17563.2 17332.399999999998 22984.7 25177.8 25000.199999999997 26871.100000000002 23539.6 20164.5 True False 12641.718852256396 15947.588640790893 16119.221491912584 18607.082515191432 21632.78513565886 24101.004186318434 26294.588029081922 28119.629403773408 20888.322365022865 23649.906957492683 0.5345356696319387 0.674319297300171 0.6815765288584252 0.7867719119840512 0.9147091011622452 1.019073953636965 1.1118262780628556 1.188995350143001 0.8832306360683206 1.0 14.529546887332812 -6.134633903701788 1.0798009754294273 1.0652861981731683 0.5953969297586619 0.8346219888826483 0.0807097464551204 0.19334700028623292 0.46542809196943397 0.033755877002245874 0.05890765012995004 7.334425411250276e-07 6.134633903701788 -0.4698892684145064 SSGS(ph)ETEQVVDFSDR ddPTM_PC-9_AZD4547_30min_R2 1 SSGSETEQVVDFSDR 15 0 O95251-2;O95251-4;O95251 O95251-2 KAT7 Histone acetyltransferase KAT7 1 S(0.089)S(0.319)GS(0.59)ET(0.001)EQVVDFSDR 128.74 1.7117e-05 7752800.0 5284.2 2405.8 7430.6 11319.0 7119.9 11423.0 6797.4 9999.9 8138.8 7292.7 True False 6964.46568181204 3183.427802016837 7332.065388932211 8709.579426806733 6131.42478341994 10708.71800421815 7402.355431691357 8454.645229841746 8569.000352310486 7037.384792725124 0.9896383226069344 0.45235949088753774 1.0418735943658664 1.2376159160445845 0.8712646762982582 1.5216899913286335 1.0518616857988952 1.2013902150954872 1.2176398768429808 1.0 12.780823684046839 -5.461858522449947 6.848668467702455 1.1630445524616437 0.7229525474143985 0.4209761310154615 0.20180145842280683 0.20680066400141595 19.347964029132015 0.0494728005064207 0.10292979527035463 3.4525619309039713e-06 5.461858522449947 -0.4400920050472452 SSGS(ph)ETEQVVDFSDR ddPTM_PC-9_Lapatinib_30min_R1 1 SSGSETEQVVDFSDR 15 0 O95251-2;O95251-4;O95251 O95251-2 KAT7 Histone acetyltransferase KAT7 1 S(0.038)S(0.117)GS(0.74)ET(0.105)EQVVDFSDR 120.59 7.9157e-05 7677400.0 7699.7 5480.9 6434.0 7607.0 7727.9 8560.6 8806.9 7335.2 10002.0 7154.9 True False 7589.900866047953 5468.20931279549 5905.021355958228 8166.444156208098 7273.360115635969 8194.48309373327 9262.878189507352 7676.020170464129 8875.469434270706 8391.614931695025 0.9044624816352085 0.6516277685886339 0.703681163163843 0.9731671701669176 0.8667414049427576 0.9765084742845873 1.1038254573051935 0.9147250240799177 1.0576592832862444 1.0 13.034732762758415 -6.08615006919592 1.3574586157533566 1.0048414712983147 0.7457229382772101 0.5532517601254228 0.09136667017898598 0.3114448357978191 1.1612091098450386 0.033338215163090885 0.05555536810585469 8.20068123208566e-07 6.08615006919592 -0.25911853302110455 SSGS(ph)HSHSPSSHY(ph)RYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGSHSHSPSSHYRYR 16 1 E5RJX3;H0YAZ8;H0YB53;E7EWW5;O43312-2;O43312-4;O43312;O43312-5 E5RJX3 MTSS1 Metastasis suppressor protein 1 2 SSGS(0.382)HS(0.085)HS(0.086)PS(0.379)S(0.154)HY(0.457)RY(0.457)R 80.632 0.028542 0.0 6407.6 3592.9 3883.9 5698.5 5963.6 5716.9 6992.0 4184.7 5025.5 4078.3 True False 7492.280124131275 3949.5793673511143 3976.506905772775 5379.23151978627 4795.075390060799 5417.095699972728 6329.66714230371 4074.856059056152 5098.988430188074 4817.663506194965 1.5551688312180914 0.8198122102700628 0.8254015459276974 1.1165643911969345 0.9953113960522315 1.124423840105678 1.3138458371292394 0.8458158303950354 1.0583944735101065 1.0 12.23411791549521 -8.063371281226924 0.010781205382365041 7.395100292836547e-05 2.078519282549408 0.025450603404138183 0.21697338075635383 6143.975669890023 65.89846272266783 6365.322483982085 6326.97112749295 8.64228767974681e-09 8.063371281226924 2.0784453315464795 SSGS(ph)HSHSPSSHY(ph)RYR ddPTM_PC-9_Lapatinib_30min_R1 1 SSGSHSHSPSSHYRYR 16 1 E5RJX3;H0YAZ8;H0YB53;E7EWW5;O43312-2;O43312-4;O43312;O43312-5 E5RJX3 MTSS1 Metastasis suppressor protein 1 2 S(0.02)S(0.006)GS(0.883)HS(0.033)HS(0.062)PS(0.063)S(0.318)HY(0.471)RY(0.143)R 78.615 0.034149 0.0 14914.0 10910.0 12143.0 8588.0 15145.0 13926.0 10323.0 11847.0 12646.0 10801.0 True False 14701.323625107356 10884.738565308406 11144.649413335514 9219.590168728168 14254.200876215624 13330.417443091552 10857.47442917308 12397.454869599824 11221.674311716382 12667.938458572167 1.1605142915072526 0.8592351944955099 0.8797524119478279 0.7277893083297572 1.1252186709645768 1.0522957217297735 0.8570829787877617 0.9786481762713876 0.8858327144874055 1.0 13.628894143366333 -4.750554210929027 24.667544459389937 0.928698527233612 1.160514879252516 0.2926694852966285 0.10771582018784134 546.7772130587317 1238989.1158568421 0.02773755531104541 0.3967384066009427 1.776011563316089e-05 4.750554210929027 0.23181635201890394 SSGS(ph)HSHSPSSHYRY(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 SSGSHSHSPSSHYRYR 16 1 E5RJX3;H0YAZ8;H0YB53;E7EWW5;O43312-2;O43312-4;O43312;O43312-5 E5RJX3 MTSS1 Metastasis suppressor protein 1 2 SSGS(0.982)HS(0.072)HS(0.05)PS(0.036)S(0.055)HY(0.19)RY(0.615)R 78.615 0.034149 0.0 1107.6 0.0 892.23 1061.6 578.71 558.86 379.22 1095.3 523.97 647.7 True False 1091.8054208910364 0.0 818.8742935073989 1139.673605393785 544.6714155876363 534.9588605662894 398.85415606228963 1146.1916365892355 464.9549809512919 759.6540819939994 1.4372402475942474 0.0 1.077956813393214 1.5002533816474475 0.7169992612399846 0.7042137641939442 0.5250470780270753 1.5088336438351284 0.6120614526691435 1.0 9.569198808594292 -7.7298390153842425 24.999754241659218 1.0453387943692505 0.8417138977635333 0.03414060369289984 0.45738058790243546 747.6000993889136 591443.3833408065 0.21295632938251113 0.1229365288882342 1.862777504513634e-08 7.7298390153842425 -0.20362489660571714 SSGS(ph)PEPSPAIAK ddPTM_PC-9_AZD4547_30min_R2 4 SSGSPEPSPAIAK 13 0 Q66K64;K7ELE9 Q66K64 DCAF15 DDB1- and CUL4-associated factor 15 1 S(0.018)S(0.018)GS(0.964)PEPSPAIAK;S(0.04)S(0.002)GS(0.958)PEPSPAIAK;SSGS(0.999)PEPSPAIAK;S(0.01)S(0.03)GS(0.959)PEPS(0.001)PAIAK 217.12 1.6065000000000002e-14 117673100.0 127628.0 121041.0 160226.0 208562.0 174236.0 159301.0 140710.0 174945.0 134983.0 155774.0 True False 168211.0491726857 160165.13616423623 158101.29855019134 160481.25315077894 150046.33893228212 149339.88328722364 153232.9174086111 147911.27008616744 142117.9258067437 150320.39967391544 1.119016777081353 1.0654916865021422 1.051762095451813 1.0675946411724893 0.9981768226918779 0.9934771568674724 1.01937539908764 0.9839733689308036 0.9454333950351046 1.0 17.19768128216964 -5.392607110936792 0.4605472372356303 0.9752532401668468 1.1549188514246498 0.8026251337167946 0.021486194111458995 1.2918743789959435 0.3201716112633604 0.016912447864986246 0.11951428189263615 4.049420611305095e-06 5.392607110936792 0.179665611257803 SSGS(ph)PEPSPAIAK ddPTM_PC-9_Lapatinib_30min_R1 4 SSGSPEPSPAIAK 13 0 Q66K64;K7ELE9 Q66K64 DCAF15 DDB1- and CUL4-associated factor 15 1 SS(0.001)GS(0.998)PEPSPAIAK;S(0.005)S(0.066)GS(0.929)PEPSPAIAK;S(0.359)S(0.209)GS(0.432)PEPSPAIAK;S(0.004)S(0.014)GS(0.982)PEPSPAIAK 208.82 4.6483999999999997e-10 110826600.0 226707.0 197162.0 245460.0 221008.0 221873.0 196300.0 179337.0 189191.0 214477.0 156325.0 True False 223474.11660702745 196705.4835025968 225279.2263030006 237261.6655810753 208822.86635910126 187904.70659764975 188622.19235731958 197981.50453570153 190320.34171706438 183345.56796003052 1.2188683865854069 1.0728674038386286 1.228713782446662 1.2940681807634342 1.1389578089208288 1.0248663694920246 1.0287796670298535 1.079827054117074 1.0380416818068618 1.0 17.48420586642385 -6.609310479576719 4.331356983665278 1.0396350359354718 1.1983516060965649 0.6798392031507701 0.054863157873280964 0.14263086669271802 4.956453056010036 0.01960104973954545 0.019660217951044067 2.4586093020435077e-07 6.609310479576719 0.15871657016109308 SSGS(ph)PYGGGYGSGGGSGGYGSR ddPTM_PC-9_AZD4547_30min_R2 40 SSGSPYGGGYGSGGGSGGYGSR 22 0 P51991;P51991-2;H7C1J8 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 1 SS(0.007)GS(0.992)PYGGGYGSGGGSGGYGSR;S(0.001)SGS(0.999)PYGGGYGSGGGSGGYGSR;SSGS(1)PYGGGYGSGGGSGGYGSR;S(0.001)S(0.002)GS(0.997)PYGGGYGSGGGSGGYGSR;S(0.003)SGS(0.997)PYGGGYGSGGGSGGYGSR;S(0.017)S(0.017)GS(0.557)PY(0.406)GGGY(0.003)GSGGGSGGYGSR;S(0.011)S(0.011)GS(0.97)PY(0.008)GGGYGSGGGSGGYGSR;SSGS(1)PYGGGYGSGGGSGGYGSR;SSGS(1)PYGGGYGSGGGSGGYGSR;S(0.001)S(0.001)GS(0.977)PY(0.009)GGGYGS(0.001)GGGS(0.006)GGY(0.004)GS(0.003)R;S(0.041)S(0.008)GS(0.951)PYGGGYGSGGGSGGYGSR;S(0.029)S(0.001)GS(0.968)PY(0.001)GGGYGS(0.001)GGGSGGYGSR;SS(0.001)GS(0.999)PYGGGYGSGGGSGGYGSR;S(0.028)S(0.081)GS(0.891)PYGGGYGSGGGSGGYGSR;S(0.001)S(0.005)GS(0.983)PY(0.01)GGGYGSGGGSGGYGSR;SS(0.002)GS(0.998)PYGGGYGSGGGSGGYGSR;SSGS(1)PYGGGYGSGGGSGGYGSR;S(0.01)S(0.01)GS(0.933)PY(0.042)GGGYGS(0.002)GGGS(0.003)GGYGSR;SSGS(1)PYGGGYGSGGGSGGYGSR;SSGS(0.999)PYGGGYGSGGGSGGYGSR;S(0.001)S(0.001)GS(0.998)PYGGGYGSGGGSGGYGSR;SSGS(1)PYGGGYGSGGGSGGYGSR;S(0.001)S(0.025)GS(0.974)PYGGGYGSGGGSGGYGSR;SSGS(0.999)PYGGGYGSGGGSGGYGSR;SSGS(1)PYGGGYGSGGGSGGYGSR;S(0.008)S(0.022)GS(0.96)PY(0.008)GGGY(0.001)GSGGGSGGYGSR;S(0.376)S(0.036)GS(0.587)PY(0.001)GGGYGSGGGSGGYGSR;S(0.013)SGS(0.987)PYGGGYGSGGGSGGYGSR;S(0.121)S(0.039)GS(0.838)PY(0.002)GGGYGSGGGSGGYGSR;S(0.003)S(0.002)GS(0.9)PY(0.095)GGGYGSGGGSGGYGSR;S(0.001)S(0.003)GS(0.994)PYGGGYGSGGGS(0.001)GGYGSR;SS(0.001)GS(0.998)PYGGGYGSGGGSGGYGSR;S(0.001)S(0.002)GS(0.575)PY(0.404)GGGY(0.017)GS(0.001)GGGSGGYGSR;SSGS(1)PYGGGYGSGGGSGGYGSR;S(0.022)S(0.001)GS(0.977)PYGGGYGSGGGSGGYGSR;S(0.081)S(0.031)GS(0.888)PYGGGYGSGGGSGGYGSR;S(0.001)S(0.002)GS(0.998)PYGGGYGSGGGSGGYGSR;S(0.003)S(0.001)GS(0.986)PY(0.01)GGGYGS(0.001)GGGSGGYGSR;S(0.006)S(0.006)GS(0.987)PYGGGYGSGGGSGGYGSR;S(0.001)S(0.002)GS(0.996)PYGGGYGSGGGSGGYGSR 327.23 4.155099999999998e-188 1551924700.0 423885.9 421118.4 581244.7999999999 779956.6 650410.5 625752.1000000001 488915.6 656350.7 468859.99999999994 572268.7 True False 558672.7988255564 557236.6873808486 573537.1141733937 600149.6560793469 560112.2289774509 586623.7222662441 532428.1412449811 554926.7807536356 493642.9824033395 552233.7469980364 1.01166001147616 1.0090594615233284 1.0385767209830317 1.0867674410370305 1.0142665710348964 1.062274309484259 0.9641354664384071 1.0048766193124534 0.8939022381134828 1.0 19.074919528134366 -7.273432206599076 24.53118740944821 0.9661349571691424 1.0371128970242234 0.4860441928486252 0.03595404640499467 527.0825248688017 1078137.1068622747 0.014691619482485697 0.009989976701128363 5.328043886365065e-08 7.273432206599076 0.07097793985508094 SSGS(ph)PYGGGYGSGGGSGGYGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 21 SSGSPYGGGYGSGGGSGGYGSR 22 0 P51991;P51991-2;H7C1J8 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 1 SSGS(0.999)PYGGGYGSGGGSGGYGSR;S(0.24)S(0.009)GS(0.751)PYGGGYGSGGGSGGYGSR;SS(0.003)GS(0.996)PYGGGYGSGGGSGGYGSR;S(0.029)S(0.029)GS(0.943)PYGGGYGSGGGSGGYGSR;SS(0.001)GS(0.999)PYGGGYGSGGGSGGYGSR;SSGS(1)PYGGGYGSGGGSGGYGSR;S(0.002)S(0.049)GS(0.949)PYGGGYGSGGGSGGYGSR;SSGS(1)PYGGGYGSGGGSGGYGSR;S(0.391)S(0.005)GS(0.604)PYGGGYGSGGGSGGYGSR;S(0.002)S(0.006)GS(0.993)PYGGGYGSGGGSGGYGSR;S(0.003)SGS(0.997)PYGGGYGSGGGSGGYGSR;S(0.031)S(0.008)GS(0.959)PY(0.001)GGGYGS(0.001)GGGSGGYGSR;S(0.011)S(0.011)GS(0.967)PY(0.005)GGGY(0.001)GS(0.001)GGGSGGY(0.001)GS(0.001)R;SSGS(1)PYGGGYGSGGGSGGYGSR;S(0.051)S(0.009)GS(0.941)PYGGGYGSGGGSGGYGSR;S(0.032)S(0.001)GS(0.967)PYGGGYGSGGGSGGYGSR;S(0.001)S(0.004)GS(0.994)PYGGGYGSGGGSGGYGSR;S(0.015)S(0.019)GS(0.965)PYGGGYGSGGGSGGYGSR;S(0.031)S(0.043)GS(0.926)PY(0.001)GGGYGSGGGSGGYGSR;S(0.001)S(0.004)GS(0.994)PYGGGYGSGGGSGGYGSR;S(0.007)S(0.007)GS(0.986)PYGGGYGSGGGSGGYGSR 324.71 6.357199999999997e-188 1422165600.0 276052.80000000005 299751.10000000003 324407.2 323866.69999999995 369716.2 303797.9 340131.19999999995 290488.3 277432.6 250849.69999999998 True False 322783.0867486713 329508.40822199424 332142.29796915664 305721.49878900865 297272.9646399485 287866.203318362 307911.5103993605 282863.2899227953 281489.5269240861 296326.76488486805 1.0892809054021237 1.1119765315496164 1.1208649954323364 1.0317039667604468 1.0031930958226067 0.9714485407020415 1.0390944959662807 0.9545654441059224 0.9499294707093142 1.0 18.176829414008992 -5.980014743413739 2.3965120324534444 0.9854485221160217 1.1086486905971826 0.8137237820600227 0.025768528399682133 0.12243461171170517 1.4173056384039802 0.008275356378886182 0.012862812159231532 1.0470930007713007e-06 5.980014743413739 0.12320016848116089 SSGS(ph)PYGGGYGSGGGSGGYGSR ddPTM_PC-9_Lapatinib_30min_R1 29 SSGSPYGGGYGSGGGSGGYGSR 22 0 P51991;P51991-2;H7C1J8 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 1 S(0.001)S(0.031)GS(0.968)PYGGGYGSGGGSGGYGSR;S(0.008)SGS(0.992)PYGGGYGSGGGSGGYGSR;S(0.003)SGS(0.997)PYGGGYGSGGGSGGYGSR;S(0.001)SGS(0.999)PYGGGYGSGGGSGGYGSR;SSGS(1)PYGGGYGSGGGSGGYGSR;SSGS(1)PYGGGYGSGGGSGGYGSR;S(0.006)S(0.099)GS(0.895)PYGGGYGSGGGSGGYGSR;SS(0.002)GS(0.998)PYGGGYGSGGGSGGYGSR;SSGS(1)PYGGGYGSGGGSGGYGSR;S(0.406)S(0.004)GS(0.59)PYGGGYGSGGGSGGYGSR;S(0.002)S(0.006)GS(0.99)PY(0.002)GGGYGSGGGSGGYGSR;S(0.001)S(0.003)GS(0.979)PY(0.012)GGGY(0.003)GS(0.002)GGGSGGYGSR;S(0.042)S(0.004)GS(0.954)PYGGGYGSGGGSGGYGSR;S(0.001)SGS(0.999)PYGGGYGSGGGSGGYGSR;S(0.222)S(0.022)GS(0.756)PYGGGYGSGGGSGGYGSR;S(0.003)S(0.042)GS(0.955)PYGGGYGSGGGSGGYGSR;S(0.002)S(0.004)GS(0.988)PY(0.006)GGGYGSGGGSGGYGSR;S(0.001)S(0.003)GS(0.992)PYGGGYGS(0.004)GGGSGGYGSR;S(0.008)S(0.025)GS(0.967)PY(0.001)GGGYGSGGGSGGYGSR;S(0.073)S(0.014)GS(0.913)PYGGGYGSGGGSGGYGSR;SSGS(1)PYGGGYGSGGGSGGYGSR;S(0.003)SGS(0.997)PYGGGYGSGGGSGGYGSR;S(0.029)S(0.09)GS(0.881)PYGGGYGSGGGSGGYGSR;SSGS(1)PYGGGYGSGGGSGGYGSR;S(0.003)S(0.007)GS(0.982)PY(0.008)GGGYGSGGGSGGYGSR;S(0.008)S(0.004)GS(0.987)PY(0.002)GGGYGSGGGSGGYGSR;S(0.011)S(0.001)GS(0.987)PY(0.001)GGGYGSGGGSGGYGSR;S(0.002)S(0.009)GS(0.985)PY(0.004)GGGYGSGGGSGGYGSR;S(0.049)S(0.005)GS(0.946)PYGGGYGSGGGSGGYGSR 309.61 6.611399999999998e-186 1254166800.0 490248.77 443038.2 527201.3 423378.60000000003 470833.9 467640.4999999999 423229.5 410165.69999999995 474625.6000000001 359466.02 True False 483257.73263918643 442012.37226808676 483856.84416987 454515.27459360653 443140.375697063 447640.6059382485 445142.25263215177 429223.4958055054 421168.26689886005 421599.24259863654 1.1462490531541323 1.0484183262370885 1.147670098237114 1.0780742199442377 1.0510938609985447 1.0617680505759433 1.05584215447922 1.0180841245346524 0.9989777597864739 1.0 18.68551274961836 -6.984598782658263 0.4827628873325845 0.9927931924165674 1.1189627092752845 0.6701401757039571 0.028579883510761864 0.6385665448566201 0.3203639332935259 0.026606331410002376 0.03056949053684354 1.0360989112557887e-07 6.984598782658263 0.12616951685871713 SSGS(ph)SPAMETR ddPTM_PC-9_AZD4547_30min_R2 1 SSGSSPAMETR 11 0 Q6P0Q8;Q6P0Q8-2;A0A669KBJ4;E7ERL6 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 S(0.001)S(0.028)GS(0.903)S(0.069)PAMETR 71.268 0.026552 1730900.0 11064.0 8517.1 10295.0 21585.0 15989.0 15557.0 11729.0 19851.0 12214.0 17939.0 True False 14582.1218545037 11270.08601403176 10158.481573366493 16608.91173492564 13769.203340229693 14584.21833070312 12772.858277916252 16783.484080599665 12859.607104624805 17310.96107020665 0.84236350572127 0.6510375691057587 0.5868236623124257 0.9594448088448837 0.7954037493578237 0.842484612584772 0.7378480158388905 0.9695293064626661 0.7428592238450048 1.0 14.079398202043235 -14.522842254651428 0.046314292793298996 1.9160879009414244 0.3129371346910954 0.2664803590038892 0.11196764845485316 825.0297106226074 2.8262949590037394 96.45441169531315 23.954976144771717 3.0002520789245225e-15 14.522842254651428 -1.603150766250329 SSGS(ph)SPAMETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGSSPAMETR 11 0 Q6P0Q8;Q6P0Q8-2;A0A669KBJ4;E7ERL6 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 S(0.006)S(0.03)GS(0.824)S(0.139)PAMETR 110.93 0.0033716 0.0 10342.0 9663.5 10557.0 9685.9 15216.0 12125.0 14341.0 13366.0 11193.0 9535.6 True False 12092.696336189156 10622.828416153385 10808.718917645456 9143.230425111487 12234.534028969943 11489.143655157395 12982.516660151234 13015.156662447616 11356.676449924407 11264.328796231937 1.0735390057359049 0.9430502791881268 0.9595528604652512 0.8116977576302652 1.0861307628966363 1.0199581229376633 1.152533532623271 1.155431175517653 1.0081982384714623 1.0 13.459473730300138 -6.340835671720215 24.999172094797274 1.0797342513306292 0.9475776969162043 0.37280558107289175 0.07785394754758024 109.08856803343113 34347.261607837994 0.02430342912121345 0.027557502237897994 4.5620950377977734e-07 6.340835671720215 -0.13215655441442486 SSGSEGS(ph)SPNWLQALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSGSEGSSPNWLQALK 16 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 S(0.015)S(0.015)GS(0.017)EGS(0.542)S(0.412)PNWLQALK;S(0.003)S(0.004)GS(0.004)EGS(0.572)S(0.418)PNWLQALK 132.08 7.8804e-06 4359600.0 41338.0 37752.0 42652.0 48379.0 50222.0 43367.0 47009.0 42456.0 38642.0 29648.8 True False 48335.70693728363 41499.76906572386 43668.985438610754 45668.48147683425 40381.35962164354 41092.758176759686 42555.967204312765 41341.574985850355 39207.06614651827 35023.892740228344 1.3800780882864392 1.184898816745671 1.246834147263496 1.3039236333766966 1.1529660600879361 1.1732778672417719 1.2150553200910503 1.18038206924856 1.119437706063014 1.0 15.096051820971216 -13.680496158102342 0.04166573936640227 5.3796182979293475e-08 1.8272922982270188 0.7135641049013947 0.05229936132107292 377.2226834574025 1.3487737627969232 50.39448055428455 16.874755551076536 2.0869105852620188e-14 13.680496158102342 1.8272922444308357 SSGSEGSS(ph)PNWLQALK ddPTM_PC-9_AZD4547_30min_R2 2 SSGSEGSSPNWLQALK 16 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 SSGSEGS(0.132)S(0.868)PNWLQALK;SSGSEGS(0.027)S(0.973)PNWLQALK 253.36 3.3177e-57 36411000.0 180319.0 175212.0 189159.0 252421.0 252573.0 198710.0 158614.0 226437.0 161442.0 199886.0 True False 237656.6911318018 231845.8525425943 186650.62806570483 194229.23831557404 217507.59867733048 186284.63228733194 172730.33872396726 191446.36465461386 169975.4945296248 192888.0519805632 1.2320964864933668 1.2019710405181383 0.9676629845611853 1.006953185131166 1.1276364525639364 0.9657655327770293 0.8954952727780817 0.9925257821251955 0.8812131844576498 1.0 17.557404256070363 -1.5228787452806811 0.4144714219171407 0.9457122751659671 6.605151944458481 0.6474220485226563 0.067947048290464 48.12625949692903 0.622949501717875 0.04833877898991522 224.90071809623416 0.029999999999976268 1.5228787452806811 5.659439669292515 SSGSEGSS(ph)PNWLQALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSGSEGSSPNWLQALK 16 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 SSGSEGS(0.35)S(0.65)PNWLQALK;SSGSEGS(0.185)S(0.815)PNWLQALK 268.13 3.6459999999999994e-69 21253000.0 104139.0 87065.0 96570.0 98560.0 102746.0 87701.0 104604.0 83334.0 84393.0 58479.0 True False 121767.67586099434 95708.23780746055 98872.59504376452 93038.00273583118 82613.65886833238 83101.8051712132 94695.15185262254 81146.5707996714 85627.08796913 69080.77978049072 1.762685312006033 1.3854539296108201 1.4312605526159303 1.3468001234419518 1.195899338873177 1.2029656502905053 1.3707886933749645 1.174662055893414 1.239521155395414 1.0 16.07599674757983 -1.5228787452803376 0.40709596375333323 1.1809772260705382 10.112789657420189 0.7573966352712878 0.09528220183560464 37.47228768511469 0.49130723110219365 0.06543095118101407 269.9330474539126 0.029999999999999995 1.5228787452803376 8.93181243134965 SSGSEGSS(ph)PNWLQALK ddPTM_PC-9_Lapatinib_30min_R1 2 SSGSEGSSPNWLQALK 16 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 SSGSEGS(0.008)S(0.992)PNWLQALK;SSGSEGS(0.057)S(0.943)PNWLQALK 254.72 2.8274999999999996e-57 24855000.0 133718.0 123645.0 159332.0 116925.0 130358.0 122517.0 98706.0 104133.0 121489.0 97981.0 True False 131811.15679912214 123358.70759922624 146232.33799930647 125524.05455036585 122690.59873368888 117277.23351107635 103816.51370783267 108971.39933620646 107805.62948411459 114916.88529852436 1.147012960338342 1.0734602428422264 1.2725052338429872 1.092302965088958 1.067646398655606 1.0205396117935186 0.9034052170674849 0.948262729651321 0.9381182687301647 1.0 16.810231270216015 -6.654375423383758 1.5116194579512339 0.943940913623352 1.1526535912806197 0.7275384089012714 0.05453672146130012 0.19932065891445983 0.9444218933966703 0.02319157741305592 0.02298164695484765 2.2162797411279916e-07 6.654375423383758 0.20871267765726775 SSGSET(ph)EQVVDFSDR ddPTM_PC-9_AZD4547_30min_R2 1 SSGSETEQVVDFSDR 15 0 O95251-2;O95251-4;O95251 O95251-2 KAT7 Histone acetyltransferase KAT7 1 SS(0.001)GS(0.468)ET(0.532)EQVVDFSDR 163.9 0.0007841 7287800.0 7593.9 7440.8 11216.0 11224.0 9289.7 10350.0 7913.5 8842.2 9814.8 10468.0 True False 10008.602237067576 9845.893087225402 11067.26851159579 8636.480209071366 7999.985506894229 9702.81286384118 8617.786169519166 7475.841163542311 10333.590290688671 10101.518506211227 0.9908017523220377 0.9746943572069243 1.095604438559484 0.8549685083248585 0.7919587042260224 0.960530128007498 0.8531178915546467 0.740071025850773 1.0229739503357587 1.0 13.3022845613098 -5.777065942291317 24.999107782739394 0.8756890777715325 1.0157996081326932 0.30524828376725466 0.08908941889671262 252.6228464503578 404141.0435304887 0.024261250143526234 0.03612598582580388 1.6708368989558036e-06 5.777065942291317 0.14011053036116072 SSGSGSSVADERVDY(ph)VVVDQQK ddPTM_PC-9_AZD4547_30min_R2 4 SSGSGSSVADERVDYVVVDQQK 22 1 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 SSGSGSSVADERVDY(1)VVVDQQK;SSGSGSSVADERVDY(1)VVVDQQK;SSGSGSSVADERVDY(1)VVVDQQK;SSGSGSSVADERVDY(1)VVVDQQK 115.38 7.3879e-06 50407500.0 90871.0 86019.0 135835.0 205137.0 176068.0 146574.0 130067.0 160755.0 131950.0 161193.0 True False 119766.08776578143 113822.95955677387 134033.73914698782 157845.83398505623 151623.99735490436 137408.70460914576 141642.71102683377 135914.00853240662 138924.607618736 155549.6821333305 0.7699539216230804 0.7317466548032526 0.8616780009367031 1.014761533551432 0.974762502085596 0.8833750267092473 0.9105946671457916 0.8737659033973916 0.8931204854514314 1.0 17.24701592115651 -5.4399085313135975 4.172950229079603 0.9296475293729375 0.7536166540684763 0.7050383704791348 0.047293644667566276 0.12911500768370535 4.073725304653314 0.013580702653396724 0.02941863958841553 3.631545323023803e-06 5.4399085313135975 -0.17603087530446115 SSGSGSSVADERVDY(ph)VVVDQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSGSGSSVADERVDYVVVDQQK 22 1 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 SSGSGSSVADERVDY(1)VVVDQQK;SS(0.002)GS(0.001)GS(0.001)S(0.001)VADERVDY(0.995)VVVDQQK 111.45 5.6521e-05 35295000.0 47676.0 27561.0 49947.0 59318.0 97229.0 84138.0 90346.0 95866.0 87572.0 79590.0 True False 55746.60515607752 30297.073935696535 51137.92590505233 55994.604771550716 78177.6754142164 79725.65516351626 81787.77283160345 93349.61907842293 88852.57483005292 94019.03696590675 0.5929289105172647 0.3222440360315846 0.5439103351334688 0.5955666700974136 0.831509000060969 0.8479735353216438 0.8699065154353941 0.9928799750658309 0.9450487656268242 1.0 16.520665282676013 -6.261639731790128 1.0490329350078655 0.9538128515972056 0.4408728054749517 0.8823581976533681 0.07387804278763102 0.15698483360280638 0.3620610054763477 0.03188086644746911 0.04878201599070698 5.474699272732114e-07 6.261639731790128 -0.512940046122254 SSGSGSSVADERVDY(ph)VVVDQQK ddPTM_PC-9_Lapatinib_30min_R1 3 SSGSGSSVADERVDYVVVDQQK 22 1 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 SSGSGS(0.001)S(0.001)VADERVDY(0.998)VVVDQQK;SSGSGSSVADERVDY(1)VVVDQQK;SSGSGSSVADERVDY(1)VVVDQQK 128.44 7.9012e-06 39012400.0 88042.0 74828.0 91780.0 66536.0 94390.0 101146.0 98201.0 85862.0 127733.0 74816.0 True False 86786.50493507468 74654.74036341875 84234.20268104518 71429.27939758923 88838.16577788015 96820.22136284201 103285.36727881672 89851.46197464144 113346.36445187949 87747.84591394622 0.9890442783083893 0.8507871570617495 0.9599574987134516 0.8140288647956041 1.0124256026182477 1.1033914320562697 1.1770701172551636 1.023973421099798 1.2917281703192758 1.0 16.421076089269647 -6.586479683051287 3.159432403889711 1.1249753139452308 0.9035707245971428 0.5654703487117805 0.0888083326798882 0.17148535504732423 3.4808589498825997 0.028646612116672097 0.02928892842011437 2.5913156441603535e-07 6.586479683051287 -0.22140458934808793 SSGSPY(ph)GGGYGSGGGSGGYGSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSGSPYGGGYGSGGGSGGYGSR 22 0 P51991;P51991-2;H7C1J8 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 1 S(0.14)S(0.013)GS(0.384)PY(0.453)GGGY(0.007)GS(0.002)GGGSGGYGSR 80.411 0.0007275000000000001 2496700.0 2059.5 4409.0 6317.4 4465.3 4104.7 3496.8 3258.1 3368.5 4411.5 5038.0 True False 2030.1311523339546 4398.791231388154 5798.007757869209 4793.693057804133 3863.269616150698 3347.2500154389318 3426.7884759942635 3525.012807313833 3914.6304148455524 5908.811587286971 0.3435768973750758 0.7444460136201191 0.9812476962954512 0.8112787126463709 0.6538149946196739 0.5664844725529352 0.579945463715094 0.5965688286453454 0.6625072329718595 1.0 12.528652281472235 -10.459199327192872 4.5263841987519005 1.0000049828531088 0.6692175623522162 0.2896203840044407 0.15916313610368352 239771328.17023116 830118711.5840337 22928.399654100853 0.04270011265962426 3.4737669012669796e-11 10.459199327192872 -0.3307874205008926 SSGSPYGGGYGS(ph)GGGSGGYGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSGSPYGGGYGSGGGSGGYGSR 22 0 P51991;P51991-2;H7C1J8 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 1 S(0.002)S(0.002)GS(0.059)PY(0.095)GGGY(0.113)GS(0.727)GGGS(0.001)GGYGSR;SSGS(0.01)PYGGGY(0.004)GS(0.966)GGGS(0.013)GGY(0.003)GS(0.005)R 105.79 0.0015850999999999999 27871000.0 13572.0 23960.0 13810.599999999999 20286.4 20909.9 20397.4 19900.1 18347.5 16375.0 13921.9 True False 15869.471540781191 26338.590453876433 14139.897080992157 19149.818777396194 16812.755197973092 19327.72443642949 18015.018463752578 17865.89756578315 16614.453396543566 16445.830264300243 0.9649541121210413 1.6015360751381997 0.8597861496653236 1.1644178779447596 1.0223111225019361 1.1752355536822676 1.095415565783787 1.0863481672047606 1.0102532453231845 1.0 14.005434223718646 -1.9324282182091141 0.15425438990273518 0.9816845984594812 1.7568072790863614 0.05993755439240711 0.18435747430771254 153.27092602942778 1.7299707991040731 0.5925921781009763 26.112630722727676 0.011683468225676173 1.9324282182091141 0.7751226806268802 SSGSPYGGGYGS(ph)GGGSGGYGSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSGSPYGGGYGSGGGSGGYGSR 22 0 P51991;P51991-2;H7C1J8 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 1 S(0.015)S(0.003)GS(0.036)PYGGGY(0.005)GS(0.924)GGGS(0.016)GGYGS(0.001)R 105.2 0.0016104 0.0 10488.0 10290.0 10906.0 9987.2 12865.0 11663.0 10721.0 13738.0 11681.0 11820.0 True False 10338.43919673636 10266.174137215716 10009.35077837743 10721.692004322536 12108.305993563159 11164.2006777809 11276.080921744124 14376.317633034723 10365.362773616886 13863.071250840014 0.7457538816378743 0.7405411074832102 0.7220153887451835 0.7733994733434606 0.8734216087095039 0.8053194328857266 0.8133898122366546 1.0370225596412201 0.7476959892988223 1.0 13.758959289802888 -6.07813794822988 0.15098536149625538 1.0602698030820967 0.5221981748382144 0.4813348850732885 0.0759087756380851 11.92119070275478 0.5361846254478533 0.4633654333488705 1.4776198428386893 8.353376414950573e-07 6.07813794822988 -0.5380716282438823 SSGSPYGGGYGSGGGS(ph)GGYGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGSPYGGGYGSGGGSGGYGSR 22 0 P51991;P51991-2;H7C1J8 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 1 SSGSPYGGGYGS(0.002)GGGS(0.953)GGY(0.001)GS(0.044)R 166.38 6.5954e-32 0.0 4051.8 4351.9 3924.2 5836.1 4020.5 3581.1 5043.8 4318.5 2619.3 3757.6 True False 4737.689713302188 4783.927871294861 4017.7678106113726 5509.122237891486 3232.7118864007407 3393.3008118337475 4566.0147500502635 4205.143950828974 2657.602307271241 4438.823134854766 1.0673301389507155 1.0777468995622386 0.9051425768832373 1.2411222683401057 0.7282813007386274 0.7644595670389946 1.0286543552944827 0.9473555992373556 0.5987177741782665 1.0 12.115961510209223 -6.271636742091997 24.98544989934979 0.8471437689972149 1.061208228578728 0.3765520004308801 0.14355158095411114 806.3848683338175 1975789.9788012092 0.04428812679163176 0.05075632296680503 5.350116733114121e-07 6.271636742091997 0.2140644595815132 SSGSPYGGGYGSGGGSGGYGSR ddPTM_PC-9_Lapatinib_30min_R1 3 SSGSPYGGGYGSGGGSGGYGSR 22 0 P51991;P51991-2;H7C1J8 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 0 ;; 244.54 5.192999999999999e-79 11740200.0 11916.8 11668.900000000001 12745.7 12179.2 11705.8 13505.599999999999 11538.9 10929.1 10759.8 11610.5 False True 11746.864246726524 11641.881378985085 11697.797745824799 13074.898996620186 11017.287858488267 12927.996971091294 12136.327781728678 11436.905884641119 9547.918018282939 13617.359454981208 0.8626389195028218 0.8549294316180002 0.8590356878290206 0.9601640494139566 0.8090619840734367 0.9493761998301553 0.8912394375613863 0.8398769175809278 0.7011578162306883 1.0 13.733159356722446 -10.64782844717737 4.828728797558603 1.0000081461950605 0.863121324672061 0.27299488013420736 0.06886708014526574 6.038332782181155e-06 1.0942487581978744e-06 0.06666743645530458 0.016168266318408994 2.2499431915688244e-11 10.64782844717737 -0.13688682152299947 SSGSS(ph)PAMETR ddPTM_PC-9_Lapatinib_30min_R1 1 SSGSSPAMETR 11 0 Q6P0Q8;Q6P0Q8-2;A0A669KBJ4;E7ERL6 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 S(0.001)S(0.005)GS(0.16)S(0.834)PAMETR 80.834 0.013849 965350.0 6795.8 5675.4 9118.0 6210.3 6886.5 8098.1 7100.9 6563.4 7366.8 6312.9 True False 6698.890645802915 5662.2589599955345 8368.353236497836 6667.026178953486 6481.449609379924 7751.76314059312 7468.549857029461 6868.359524869708 6537.073408156906 7404.076353589496 0.9047570994530997 0.7647488612472874 1.1302359452899022 0.9004534611155532 0.8753893530876026 1.0469588332696036 1.0087078388121578 0.9276456909496791 0.8829019442766461 1.0 12.854104057555196 -5.230963681862832 24.997589228170547 0.9670012733046826 0.8347529929367195 0.30729091237610806 0.0819214404733903 857.0708241173809 703006.8905582528 0.020610084737493685 0.054515330192728736 5.8753848373439365e-06 5.230963681862832 -0.1322482803679631 SSGSSSSGLGTVSNS(ph)PASQR ddPTM_PC-9_AZD4547_30min_R2 2 SSGSSSSGLGTVSNSPASQR 20 0 Q9UPP1-4;Q9UPP1-3;Q9UPP1-2;Q9UPP1;H0Y3N9;Q9UPP1-5;H0Y589 Q9UPP1-4 PHF8 Histone lysine demethylase PHF8 1 SSGSSSSGLGTVSNS(0.999)PAS(0.001)QR;SSGSSSSGLGTVS(0.054)NS(0.922)PAS(0.023)QR 308.45 5.011299999999998e-139 36488000.0 14038.9 18022.6 22973.5 25689.0 20995.3 21717.0 19759.8 24592.0 17643.3 23399.0 True False 18502.978172739688 23848.052998848052 22668.856379381756 19766.797941093573 18080.46500025795 20359.032556911992 21518.383920195196 20791.87146794151 18575.88881848917 22579.808132101312 0.8194479804473773 1.0561672118437402 1.003943711423918 0.875419216383485 0.8007359891846589 0.9016477216193842 0.9529923281147323 0.9208170125406014 0.822677000168135 1.0 14.462745606668246 -5.769739132463977 24.99697029523538 0.8916275293954001 0.9694843949802019 0.11655569849579972 0.0780724708353284 315.952612211561 951579.606949016 0.021793922338323682 0.03293945814940317 1.6992640423944503e-06 5.769739132463977 0.07785686558480176 SSGSSSSGLGTVSNS(ph)PASQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSGSSSSGLGTVSNSPASQR 20 0 Q9UPP1-4;Q9UPP1-3;Q9UPP1-2;Q9UPP1;H0Y3N9;Q9UPP1-5;H0Y589 Q9UPP1-4 PHF8 Histone lysine demethylase PHF8 1 SSGSSSSGLGTVS(0.002)NS(0.998)PASQR;SSGSSSSGLGTVS(0.001)NS(0.999)PASQR;SSGSSSSGLGTVSNS(1)PASQR 268.43 3.245299999999999e-157 26325000.0 16115.2 17231.6 21665.0 18788.3 24499.7 23498.699999999997 23949.6 20347.800000000003 23668.7 16823.6 True False 18843.18507029158 18942.239368322917 22181.57576497004 17735.652463490445 19699.15965756801 22266.386804902853 21680.920507911447 19813.69181027621 24014.80996071882 19873.58550445568 0.9481522630159975 0.9531364817926813 1.1161335613041192 0.8924233857807938 0.9912232321214224 1.1204010871571566 1.0909415667872593 0.996986266309819 1.208378324854097 1.0 14.278564560282142 -6.69639271303825 7.455055383534457 1.0834835439382065 0.9807559872436686 0.30915483392631815 0.07713354765753262 0.2971018955780434 28.7871369854425 0.0247667946198433 0.02466749999832154 2.0119041523032058e-07 6.69639271303825 -0.10272755669453781 SSGSSSSGLGTVSNS(ph)PASQR ddPTM_PC-9_Lapatinib_30min_R1 3 SSGSSSSGLGTVSNSPASQR 20 0 Q9UPP1-4;Q9UPP1-3;Q9UPP1-2;Q9UPP1;H0Y3N9;Q9UPP1-5;H0Y589 Q9UPP1-4 PHF8 Histone lysine demethylase PHF8 1 SSGSSSSGLGTVS(0.001)NS(0.999)PASQR;SSGSSSSGLGTVSNS(1)PASQR;SSGSSSSGLGTVSNS(0.997)PAS(0.002)QR 372.52 0.0 31158000.0 43437.0 37577.0 39966.1 35802.5 32496.7 31751.8 36783.0 32029.0 36945.4 23259.5 True False 42817.580414629796 37489.99276522399 36680.24153160738 38435.53528363882 30585.30799697038 30393.849531060943 38687.44375939874 33517.18426761312 32784.219999690555 27279.873583664383 1.569566672782151 1.3742729653876986 1.3445898647262093 1.4089337755089386 1.1211675121282578 1.1141492073944674 1.4181679999633645 1.2286414804973194 1.2017731643493488 1.0 14.735549338404091 -1.5228787452803376 0.17536181184018065 1.0656215217373741 2.897411919947468 0.5819932424004006 0.10672297416943785 48.69120085723174 0.5387611931872633 0.27382470324166114 23.591265594419163 0.029999999999999995 1.5228787452803376 1.8317903982100938 SSGT(ph)ASSVAFTPLQGLEIVNPQAAEKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGTASSVAFTPLQGLEIVNPQAAEKK 27 1 E7EVX8;Q8WWY3 E7EVX8 PRPF31 U4/U6 small nuclear ribonucleoprotein Prp31 1 S(0.226)S(0.226)GT(0.251)AS(0.226)S(0.067)VAFT(0.003)PLQGLEIVNPQAAEKK 56.22 0.0031178 8116800.0 16042.0 9727.1 12009.0 19382.0 16669.0 14488.0 15797.0 17857.0 14701.0 15421.0 True False 18757.593756057475 10692.742203835624 12295.340104386121 18296.089377291824 13402.829109417713 13728.223775333647 14300.593799624083 17388.272671055453 14915.974313440425 18216.705227431157 1.029691896634076 0.5869745417922354 0.6749486227548711 1.0043577666141914 0.735743864880429 0.7536062972936156 0.7850263602053515 0.9545234691985777 0.8188074696943325 1.0 14.152974428597284 -8.527695253108948 0.6551020665373616 0.9967981198050384 0.7841831689236736 0.1536956706284014 0.13472235781279612 1.4717370044661526 1.4565160605738372 0.13514001628166974 0.055497770965723184 2.966912558555774e-09 8.527695253108948 -0.21261495088136484 SSGTAS(ph)SVAFT(ph)PLQGLEIVNPQAAEKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGTASSVAFTPLQGLEIVNPQAAEKK 27 1 E7EVX8;Q8WWY3 E7EVX8 PRPF31 U4/U6 small nuclear ribonucleoprotein Prp31 2 S(0.013)S(0.013)GT(0.049)AS(0.467)S(0.467)VAFT(0.993)PLQGLEIVNPQAAEKK 97.059 9.015200000000001e-09 1510600.0 10069.0 2568.9 6345.6 9874.8 6039.0 9223.3 7054.8 9946.6 8661.0 5895.2 True False 11773.482828184931 2823.9234147313523 6496.903169822011 9321.546970533549 4855.701301324228 8739.613911308314 6386.51827167108 9685.512289293842 8787.650739997795 6963.953093622477 1.6906321265958808 0.4055058063670008 0.9329332180269585 1.3385424693727668 0.6972622066870372 1.2549788595376912 0.9170823217519648 1.3908066523543563 1.2618767849033106 1.0 12.765690770272276 -7.753811148630375 24.994157478090617 1.2447563003613171 1.013078213862895 0.052291899117523855 0.3449020450319182 427.9697859522502 1402270.0605867049 0.15765635564521777 0.0888043325529188 1.762742401872898e-08 7.753811148630375 -0.23167808649842203 SSGTAS(ph)SVAFTPLQGLEIVNPQAAEKK ddPTM_PC-9_AZD4547_30min_R2 1 SSGTASSVAFTPLQGLEIVNPQAAEKK 27 1 E7EVX8;Q8WWY3 E7EVX8 PRPF31 U4/U6 small nuclear ribonucleoprotein Prp31 1 S(0.101)S(0.121)GT(0.146)AS(0.486)S(0.146)VAFTPLQGLEIVNPQAAEKK 100.38 7.668700000000001e-10 6558600.0 16750.0 10090.0 12699.0 24050.0 18450.0 14200.0 15809.0 15505.0 11203.0 16924.0 True False 22076.151578356545 13351.395179295816 12530.602962620802 18505.644068796013 15888.535970181865 13312.071755221717 17215.970373908953 13109.058519454828 11795.167708622199 16331.495911264685 1.3517531828256755 0.8175243255020296 0.7672660869956065 1.1331260877352762 0.972876952393731 0.8151164980569653 1.0541575901834075 0.8026857178718593 0.7222343729386391 1.0 13.995369322618116 -4.755023447006356 24.998856305674256 0.9000059867795195 1.3517539358337356 0.5268940134272009 0.12888756603001925 179.91173648767943 700937.5744372066 0.03270274225728576 0.3014071719613053 1.7578287084620023e-05 4.755023447006356 0.4517479490542161 SSGTPGCS(ph)SGTERPQSPGSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGTPGCSSGTERPQSPGSSK 21 1 Q8IYD8-2;Q8IYD8-3;Q8IYD8 Q8IYD8-2 FANCM Fanconi anemia group M protein 1 S(0.01)S(0.01)GT(0.216)PGCS(0.633)S(0.028)GT(0.034)ERPQS(0.05)PGS(0.015)S(0.005)K 48.51 0.025682 7911000.0 7669.7 10237.0 10406.0 18248.0 12953.0 13008.0 14680.0 12320.0 11260.0 12139.0 True False 8968.028726520015 11253.261706023915 10654.118504974764 17225.623720814227 10414.952633888523 12325.837580724734 13289.404126003776 11996.613054119009 11424.656198172856 14339.704607728867 0.6253984284785332 0.7847624490087886 0.7429803330280854 1.2012537351383024 0.7263017557750132 0.8595600758805944 0.9267557798116011 0.8366011282863547 0.7967148913245502 1.0 13.807727684945332 -5.064517240529201 1.8559625474359498 0.8896256991501127 0.6277970001520495 0.28848647842864983 0.1296753861526033 0.6522351318459857 3.4639150853867418 0.0355113200174254 0.2449702545395483 8.619513604663199e-06 5.064517240529201 -0.26182869899806316 SSGTPGCSSGTERPQS(ph)PGSSK ddPTM_PC-9_AZD4547_30min_R2 1 SSGTPGCSSGTERPQSPGSSK 21 1 Q8IYD8-2;Q8IYD8-3;Q8IYD8 Q8IYD8-2 FANCM Fanconi anemia group M protein 1 SSGT(0.001)PGCS(0.073)S(0.096)GT(0.096)ERPQS(0.728)PGS(0.004)S(0.001)K 67.217 0.0017687000000000002 12401000.0 14277.0 17262.0 22812.0 26752.0 24424.0 22147.0 18274.0 21892.0 19620.0 20685.0 True False 18816.789019952022 22841.603923191713 22509.497974903985 20584.739714279873 21033.149188927997 20762.144588936295 19900.350598571196 18509.09442811383 20657.073144976133 19960.82444602399 0.9426859632393666 1.1443216679229673 1.12768378058591 1.031256988905594 1.053721465553874 1.0401446415742572 0.9969703732620703 0.9272710392380945 1.0348807585996693 1.0 14.284883689384264 -7.081697046068815 1.8808259468417592 0.982225610254314 1.06837503097614 0.24526947851595315 0.05727865794594898 0.4458610849733053 3.1299330460114207 0.02713627647144499 0.019616486136073683 8.285199187844257e-08 7.081697046068815 0.08614942072182596 SSGTPGCSSGTERPQS(ph)PGSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSGTPGCSSGTERPQSPGSSK 21 1 Q8IYD8-2;Q8IYD8-3;Q8IYD8 Q8IYD8-2 FANCM Fanconi anemia group M protein 1 SSGTPGCS(0.004)S(0.004)GT(0.002)ERPQS(0.956)PGS(0.025)S(0.009)K 83.24700000000001 0.00025906 7592700.0 32269.0 31564.0 32382.0 38490.0 37802.0 41260.0 37872.0 29546.0 34048.0 27666.0 True False 37731.504358198414 34697.465320791154 33154.109689418874 36333.53008626367 30394.969463927577 39096.25296592121 34284.48999046423 28770.448806574692 34545.88758751238 32681.626796064502 1.1545173253964829 1.0616810949254643 1.0144571412036094 1.1117417842443182 0.9300323283658486 1.1962762199655603 1.0490447799432292 0.8803248683458808 1.0570430842712017 1.0 14.996192177971881 -1.5228787452803376 0.23026003396751776 0.9923963116489838 1.7019193470904104 0.1593276323129128 0.08356379633728259 102.55597066647461 1.3431203510964447 0.1234100133525124 27.43412249304186 0.029999999999999995 1.5228787452803376 0.7095230354414266 SSGTPGCSSGTERPQS(ph)PGSSK ddPTM_PC-9_Lapatinib_30min_R1 2 SSGTPGCSSGTERPQSPGSSK 21 1 Q8IYD8-2;Q8IYD8-3;Q8IYD8 Q8IYD8-2 FANCM Fanconi anemia group M protein 1 SSGT(0.003)PGCS(0.043)S(0.043)GT(0.037)ERPQS(0.829)PGS(0.043)S(0.003)K;SSGTPGCS(0.032)S(0.028)GT(0.009)ERPQS(0.568)PGS(0.181)S(0.181)K 63.906000000000006 0.0023581 18314700.0 46514.2 44154.3 51965.7 45738.0 45719.1 47567.0 41094.6 46281.0 51875.0 31190.8 True False 45850.89897834038 44052.06343118212 47693.28073940289 49101.725097495204 43029.99242520896 45532.6702940928 43222.277310577905 48431.38421709707 46032.29123203286 36582.08822087147 1.2533701931258452 1.204197616199743 1.3037331398755982 1.3422340682421954 1.1762585056765218 1.244671163088899 1.1815147634442027 1.3239097758630718 1.2583286922852506 1.0 15.158849810565759 -11.82519669530219 1.9678077842504678 1.1934915093335347e-05 1.25415217194558 0.6671152248915753 0.0538793488895802 1197941.19089042 165975.8975120962 5313104.375940369 0.014508893003954736 1.4955581529234117e-12 11.82519669530219 1.2541402370304866 SSGVVPQS(ph)APPVPTASSR ddPTM_PC-9_AZD4547_30min_R2 4 SSGVVPQSAPPVPTASSR 18 0 P41162 P41162 ETV3 ETS translocation variant 3 1 S(0.003)SGVVPQS(0.996)APPVPTASSR;SSGVVPQS(0.999)APPVPT(0.001)ASSR;SSGVVPQS(1)APPVPTASSR;SSGVVPQS(1)APPVPTASSR 225.69 6.6003e-35 92616000.0 161347.0 130665.0 200743.0 266903.0 200623.0 177306.0 187132.0 199964.0 171528.0 190390.0 True False 212651.98977391623 172899.90595665903 198081.01665685404 205372.63696024366 172769.9594550565 166219.02779093926 203786.3854772806 169064.158515593 180594.61989864783 183724.50405020628 1.157450340515302 0.9410824476054146 1.0781415232598728 1.1178293174443492 0.9403751576210202 0.9047188814047183 1.1091954583346815 0.9202047347445442 0.9829642530932992 1.0 17.487184531556196 -6.268730199180324 24.94231954459057 0.9753247263885417 1.0644810617090943 0.29058343286239197 0.07398420754095854 774.1830020703096 2648518.8130171346 0.022532674498299935 0.026091589193349144 5.386042807746426e-07 6.268730199180324 0.08915633532055256 SSGVVPQS(ph)APPVPTASSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSGVVPQSAPPVPTASSR 18 0 P41162 P41162 ETV3 ETS translocation variant 3 1 SSGVVPQS(1)APPVPTASSR;SSGVVPQS(0.996)APPVPT(0.004)ASSR;SSGVVPQS(0.999)APPVPT(0.001)ASSR;SSGVVPQS(0.993)APPVPT(0.006)ASSR 165.49 1.4172e-07 47336400.0 28344.7 30082.5 25196.1 50087.1 103165.0 143451.0 153381.0 159014.0 152476.0 121101.0 True False 33142.897876656425 33068.891791683556 25796.870580741353 47280.88217156914 82950.55882614903 135928.17702894713 138851.64129772352 154840.05098925973 154705.67304374836 143055.6526650117 0.2316783521603719 0.23116102842241262 0.1803275166004727 0.330506913154177 0.5798481729372231 0.9501769031612143 0.9706127560220736 1.0823763207165475 1.081436980375862 1.0 17.126216979512513 -6.557913234282784 1.51225419473579 1.0500928646980152 0.21153662971659737 0.9895513319390328 0.03775991362938015 0.03494912235940894 0.1641242070794378 0.015645365938312557 0.01678386823473061 2.7674944953089267e-07 6.557913234282784 -0.8385562349814178 down SSGVVPQS(ph)APPVPTASSR ddPTM_PC-9_Lapatinib_30min_R1 3 SSGVVPQSAPPVPTASSR 18 0 P41162 P41162 ETV3 ETS translocation variant 3 1 S(0.134)S(0.003)GVVPQS(0.856)APPVPT(0.002)AS(0.002)S(0.002)R;SSGVVPQS(0.998)APPVPT(0.001)ASSR;SSGVVPQS(0.557)APPVPT(0.113)AS(0.217)S(0.113)R 133.93 4.5821e-05 47192000.0 57952.3 43889.100000000006 54700.1 57037.0 171128.0 264602.0 230048.0 200614.0 270666.0 180927.0 True False 57125.88957484977 43787.47748548827 50202.868926492156 61231.69124985431 161062.58749059288 253285.58927738818 241958.7598064913 209935.25881741397 240180.74484066325 212199.9908799269 0.26920778524997385 0.20635004414427785 0.23658280435506424 0.28855652159053197 0.7590131687693142 1.193617342899461 1.1402392563881087 0.9893273696519883 1.13186029765934 1.0 17.69506506868438 -6.411860550180441 2.580787899070683 1.0924974624771175 0.2354470789245052 0.9732617560198259 0.06560868825785666 0.041828760726559375 0.5440412322905157 0.02275550499709102 0.026080838375187567 3.873820114101084e-07 6.411860550180441 -0.8570503835526123 down SSHET(ph)LNIVEEK ddPTM_PC-9_AZD4547_30min_R2 1 SSHETLNIVEEK 12 0 E9PK52;E9PHY5;O43491-4;E9PMG5 E9PK52 EPB41L2 Band 4.1-like protein 2 1 S(0.187)S(0.187)HET(0.625)LNIVEEK 91.20700000000001 0.013694 1540700.0 5520.9 5660.7 18207.0 21866.0 21549.0 25261.0 16461.0 23009.0 21320.0 18761.0 True False 7276.431358146192 7490.410573978175 17965.563283757543 16825.131526332367 18557.29331281566 23681.425676665905 17925.997110817592 19453.48774422032 22446.93167435735 18104.183100403963 0.4019198943024295 0.4137392188555053 0.9923432161574124 0.9293504950221666 1.0250279291751963 1.308063752190923 0.9901577448373026 1.07452999322495 1.2398754227058435 1.0 14.14403546033566 -5.2977928174189355 1.940607314377965 1.0937391027239585 0.3398386668710925 0.8450940231414643 0.11312364857448926 0.1360483752259103 0.9263857957229029 0.03239881544594039 0.12366914360180813 5.037408638369459e-06 5.2977928174189355 -0.753900435852866 down SSHS(ph)HSSSHKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSHSHSSSHKR 11 1 Q9P2Q2 Q9P2Q2 FRMD4A FERM domain-containing protein 4A 1 SS(0.002)HS(0.915)HS(0.028)S(0.028)S(0.028)HKR 66.538 0.019231 11523000.0 5478.3 5796.4 5020.7 5461.1 15730.0 17438.0 7439.2 15496.0 15845.0 24966.0 True False 6405.667988642918 6371.828284926941 5140.412529110781 5155.132272125084 12647.819418749816 16523.52058215544 6734.50512085608 15089.24641936916 16076.703149205065 29492.13816925274 0.21719917192444183 0.21605175753482467 0.17429772299351148 0.17479683034645507 0.4288539320603041 0.5602686548980761 0.22834916485903323 0.5116362310787141 0.5451182636179955 1.0 14.848042800604713 -11.239701599536827 0.14598884538407128 1.9042236599021594 2.5674114160594748e-14 0.8316341350518948 0.10201284301420316 16.41982748362537 0.3793541738543653 5.914497749789842 0.7439139121080751 5.7583545364084804e-12 11.239701599536827 -1.9042236599021336 SSHYDELLAAEAR ddPTM_PC-9_AZD4547_30min_R2 2 SSHYDELLAAEAR 13 0 Q7KZF4;H7C597 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 ; 158.25 7.0484e-05 10804200.0 15588.3 13679.3 59201.0 95484.0 69451.0 61440.0 35411.0 67488.0 45039.0 59581.0 False True 20545.055143217633 18100.866211708748 58415.956058753734 73471.63901309425 59808.92746152312 57598.14708738183 38562.51039980324 57059.28031995922 47419.66959105916 57495.08732504499 0.3573358368353701 0.3148245711738222 1.016016476825275 1.2778768140263321 1.0402441363972017 1.0017924968398466 0.6707096587538415 0.9924201001274777 0.824760371664016 1.0 15.811151069613727 -5.260671205845308 24.994457019610476 0.9805179885782 0.3360801418702335 0.753742896419614 0.14675445535313522 32.926184866433836 1071287.2744022338 0.0415387013389777 0.09756893428266906 5.486922097032484e-06 5.260671205845308 -0.6444378467079666 SSHYDELLAAEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSHYDELLAAEAR 13 0 Q7KZF4;H7C597 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 ; 148.13 9.558e-05 5586300.0 18977.6 22391.0 41213.0 41795.0 43362.0 42563.0 37703.0 36399.0 40175.0 31232.0 False True 22190.132855314565 24613.830503036206 42195.67422117286 39453.36165121823 34865.5273767215 40330.92135212076 34131.49889391827 35443.56481792841 40762.483371367176 36894.114367624046 0.6014545473081535 0.6671478886246354 1.1436966287013284 1.069367359197 0.9450159727188706 1.093153258816605 0.9251204285274816 0.9606834430217805 1.1048505722402642 1.0 15.171103064401684 -5.195152512225152 6.355111482770579 1.0253983753976375 0.6258684020469157 0.8340511621689708 0.070672770568361 0.08728173346486748 6.668710486061549 0.018203769911736657 0.04924005399968865 6.380393850368733e-06 5.195152512225152 -0.3995299733507217 SSHYDELLAAEAR ddPTM_PC-9_Lapatinib_30min_R1 1 SSHYDELLAAEAR 13 0 Q7KZF4;H7C597 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 142.12 6.7259e-05 8188900.0 28198.0 28481.0 45103.0 26634.0 34694.0 50785.0 32982.0 32728.0 53270.0 31819.0 False True 27795.891349120102 28415.053994367416 41394.80544261484 28592.753208419435 32653.367131028383 48613.04393561719 34689.64657783458 34248.66235943809 47270.17164203159 37318.87175384757 0.7448213207639203 0.7614124612820812 1.1092191027545477 0.7661741061470201 0.87498269900568 1.3026397007997756 0.9295470347186497 0.9177303800966882 1.2666559684285752 1.0 15.187617749990627 -6.561302311603083 24.99994842504964 1.0708123680148478 0.8535416304618617 0.36466783269755176 0.1529100888207995 195.88462334001898 127449.32162447233 0.050289072870423106 0.05028915456220971 2.745982014549495e-07 6.561302311603083 -0.2172707375529861 SSHYGGS(ph)LPNVNQIGSGLAEFQSPLHSPLDSSR ddPTM_PC-9_AZD4547_30min_R2 2 SSHYGGSLPNVNQIGSGLAEFQSPLHSPLDSSR 33 0 Q53ET0 Q53ET0 CRTC2 CREB-regulated transcription coactivator 2 1 S(0.088)S(0.088)HY(0.048)GGS(0.776)LPNVNQIGSGLAEFQSPLHSPLDSSR;S(0.024)S(0.024)HY(0.241)GGS(0.711)LPNVNQIGSGLAEFQSPLHSPLDSSR 73.259 2.8301e-06 19005500.0 16232.6 13761.8 55999.0 149628.0 95996.0 59083.0 33978.0 93593.0 46237.0 69300.0 True False 21394.229140945106 18210.03272333332 55256.41667090337 115133.57632955542 82668.61241157602 55388.53066998341 37001.97617589209 79130.35240318178 48680.99342529368 66873.8280932784 0.31991931299496634 0.2723043265585635 0.8262786540921423 1.7216537412657509 1.236187829658359 0.8282542251465728 0.5533102744511679 1.1832783416078332 0.7279528451308546 1.0 16.029154084173705 -5.3534191991179805 4.315611790031494 1.037641304668894 0.2953371012260925 0.4781783378763388 0.3029065086925163 0.19285793699304513 6.255311864991248 0.08708575590364334 0.1951105403506598 4.431806609831306e-06 5.3534191991179805 -0.7423042034428013 SSHYGGS(ph)LPNVNQIGSGLAEFQSPLHSPLDSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSHYGGSLPNVNQIGSGLAEFQSPLHSPLDSSR 33 0 Q53ET0 Q53ET0 CRTC2 CREB-regulated transcription coactivator 2 1 S(0.021)S(0.021)HY(0.262)GGS(0.688)LPNVNQIGS(0.006)GLAEFQS(0.002)PLHSPLDSSR;S(0.046)S(0.046)HY(0.213)GGS(0.694)LPNVNQIGS(0.002)GLAEFQSPLHSPLDSSR 76.557 5.5661e-08 9055200.0 1398.3 4651.5 25051.1 25289.9 37722.8 39808.0 23957.6 20474.9 29004.1 18179.1 True False 1635.0045723161172 5113.2701793074375 25648.41323082581 23872.988893962065 30331.28813538559 37720.39840202112 21688.162689996472 19937.45556994979 29428.230092133683 21474.82692432359 0.07613586726811844 0.23810530335477867 1.1943478436967043 1.1116731686867372 1.412411296364427 1.756493709353107 1.0099342251476422 0.92841053575 1.3703593605591122 1.0 14.390358883605796 -5.239041156592471 3.736217383310914 1.24156394647549 0.10600606664833585 0.7717879031314735 0.23246875891944593 0.10434420949409147 3.2174785589898107 0.06542276458289788 0.18301366049345272 5.7671180781052624e-06 5.239041156592471 -1.1355578798271542 down SSINSVDGES(ph)PNGSSDR ddPTM_PC-9_AZD4547_30min_R2 2 SSINSVDGESPNGSSDR 17 0 Q9NUY8-2;Q9NUY8;E9PGE5 Q9NUY8-2 TBC1D23 TBC1 domain family member 23 1 SSINS(0.057)VDGES(0.927)PNGS(0.012)S(0.004)DR;SSINS(0.001)VDGES(0.945)PNGS(0.04)S(0.014)DR 92.679 0.0020050999999999997 8877600.0 17512.4 16524.0 23009.0 30324.0 24614.0 21952.0 19361.0 24926.6 19781.6 20466.0 True False 23080.97891945141 21865.05985556828 22703.885626186475 23333.270301129745 21196.770968566725 20579.337969762488 21084.091492773176 21074.7667262846 20827.214991063192 19749.491569365586 1.1686872463721272 1.1071201392082548 1.1495934235291199 1.1814618224057543 1.0732818560983153 1.042018620959545 1.067576419307814 1.0671042670776758 1.0545696793212296 1.0 14.269527892596326 -6.402822236633361 4.983336835491515 1.052344262251813 1.1479523747897915 0.7897347805226131 0.025675530269146034 0.10858525573268589 3.978167989566683 0.007986172509321213 0.009046542494326324 3.9552848279035627e-07 6.402822236633361 0.0956081125379784 SSINSVDGES(ph)PNGSSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSINSVDGESPNGSSDR 17 0 Q9NUY8-2;Q9NUY8;E9PGE5 Q9NUY8-2 TBC1D23 TBC1 domain family member 23 1 SSINSVDGES(0.904)PNGS(0.074)S(0.022)DR;SSINSVDGES(1)PNGSSDR 223.86 7.0941e-29 13672300.0 30377.0 31348.0 34722.0 34074.0 40922.0 32743.0 29716.0 26528.0 31983.0 27187.0 True False 35519.22612690175 34460.02226828543 35549.90416391828 32164.944249398497 32903.62786103496 31025.899439242785 26901.08535479076 25831.66810873937 32450.690869108566 32115.787887826427 1.1059739917003688 1.0729932078467734 1.1069292239719135 1.0015305980268572 1.0245312360375616 0.9660637798334455 0.837628067813578 0.804329266308641 1.0104279858383636 1.0 14.970995069670407 -6.547441371069581 1.3071253416767448 0.8995231315783652 1.085946382575444 0.5443514771241992 0.06545381040179808 0.3080580825920492 1.0946523454224462 0.028879504651020932 0.031639683495548236 2.8350363321789654e-07 6.547441371069581 0.1864232509970789 SSINSVDGES(ph)PNGSSDR ddPTM_PC-9_Lapatinib_30min_R1 3 SSINSVDGESPNGSSDR 17 0 Q9NUY8-2;Q9NUY8;E9PGE5 Q9NUY8-2 TBC1D23 TBC1 domain family member 23 1 SSINSVDGES(1)PNGSSDR;SSINSVDGES(1)PNGSSDR;SSINSVDGES(1)PNGSSDR 310.98 1.3245999999999996e-129 44885600.0 114602.0 91065.0 94885.0 90997.0 96325.0 84007.0 79778.0 73285.0 93983.0 71042.0 True False 112967.75446456729 90854.14458751697 87083.92156669204 97689.22293709341 90659.35288223637 80414.21643988168 83908.51448324807 76690.08864004587 83397.64485513525 83321.51504248542 1.3558053331959379 1.0904043756428419 1.0451552821895782 1.1724369496555833 1.0880665436293304 0.9651074683277024 1.0070449924063831 0.9204115959838439 1.0009136873304694 1.0 16.346401451818174 -1.5228787452803376 0.41431336490464765 0.9787993700187799 6.7494055239708395 0.713851424007596 0.06335114989072184 45.534634088599546 0.5895568764189804 0.04672826120346617 216.86154331105394 0.029999999999999995 1.5228787452803376 5.77060615395206 SSISGS(ph)LPSSGSLQAVSSR ddPTM_PC-9_AZD4547_30min_R2 1 SSISGSLPSSGSLQAVSSR 19 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 S(0.001)S(0.001)IS(0.007)GS(0.696)LPS(0.078)S(0.078)GS(0.065)LQAVS(0.038)S(0.038)R 68.123 0.0086714 5120100.0 5163.6 6598.7 12760.0 14773.0 15444.0 15540.0 10541.0 17703.0 12299.0 12575.0 True False 6805.517390447878 8731.60073038843 12590.794062764102 11367.313090574777 13299.867182844908 14568.28134339053 11479.128579377206 14967.40812447009 12949.10003109385 12134.75307753211 0.560828666802336 0.7195532265551635 1.0375813980159487 0.9367568518243462 1.0960146529450232 1.200542050613636 0.9459713358841381 1.2334332663251906 1.0671086546515338 1.0 13.566857131842017 -4.878900573190016 0.9924175067506587 1.0954425014520994 0.3067852373826359 0.7827266308044265 0.0913648068233061 0.7113406606289697 0.6248229270899708 0.029474603210450284 0.5810800144874858 1.3215981645079725e-05 4.878900573190016 -0.7886572640694636 SSISGS(ph)LPSSGSLQAVSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSISGSLPSSGSLQAVSSR 19 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 SSIS(0.083)GS(0.905)LPS(0.004)S(0.006)GS(0.002)LQAVSSR 144.17 3.9517000000000004e-10 0.0 2849.3 4900.4 4488.8 4976.7 9689.5 9736.4 9124.5 10706.0 10805.0 8652.8 True False 3331.630213759789 5386.8793263846455 4595.830015868801 4697.871633679095 7790.912031657749 9225.80604404739 8260.161304340698 10424.978843944655 10963.002683948293 10221.484144472886 0.32594388120841705 0.5270153776345209 0.4496245311258372 0.45960758411188246 0.7622094718867776 0.9025896742241786 0.8081176067574547 1.0199085276262747 1.0725450951148197 1.0 13.31931706823362 -6.5461940691459395 0.8702320789088377 1.0190469934288682 0.3951911302048111 0.913799357904422 0.07584428737462634 0.1664365092812457 0.27730945127005097 0.045157024861406006 0.05336719388025693 2.8431903134575665e-07 6.5461940691459395 -0.6238558632240571 down SSISGS(ph)LPSSGSLQAVSSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSISGSLPSSGSLQAVSSR 19 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 SSIS(0.043)GS(0.955)LPS(0.001)SGSLQAVSSR 114.99 7.6343e-05 4087700.0 7745.8 4734.8 7854.1 7686.4 7824.6 8829.2 7242.6 10438.0 12219.0 10195.0 True False 7635.343471594251 4723.836861505248 7208.366215702751 8251.683497078735 7364.372411755488 8451.595697870454 7617.58638968603 10922.987585792433 10842.767548225725 11957.192166016412 0.6385565578928049 0.39506238554322853 0.6028477351221033 0.6901021061224458 0.6158947944891112 0.7068210981747681 0.6370715034032828 0.9135077394538078 0.9067988034048665 1.0 13.545591029641953 -7.666133583067178 0.5599856918621593 1.0213279139665654 0.5416709958379818 0.7714283362873533 0.0820582223656359 0.3774229084243326 0.25343713967783177 0.08082709626045355 0.051182811774287414 2.157080818423668e-08 7.666133583067178 -0.4796569181285836 SSKAS(ph)LGSLEGEAEAEASSPK ddPTM_PC-9_AZD4547_30min_R2 1 SSKASLGSLEGEAEAEASSPK 21 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(0.141)S(0.141)KAS(0.424)LGS(0.294)LEGEAEAEASSPK 83.31700000000001 0.00025528 9325700.0 55565.0 51056.0 84254.0 143680.0 149090.0 111190.0 97358.0 111000.0 105700.0 156290.0 True False 73233.51417620182 67558.85354550327 83136.73690941429 110556.79583387155 128391.42698072702 104237.27172275372 106022.67339256279 93847.50052624874 111287.0862091733 150818.33467097362 0.485574345691912 0.4479485448031909 0.55123760046009 0.7330461251615267 0.8512985325081774 0.6911445611049778 0.7029826554169467 0.6222552498738773 0.7378883108075555 1.0 17.202452299137605 -5.013801970373715 0.11651611681318885 1.0950455870577283 1.894057521436299e-28 0.6497247562999052 0.0935911811910285 30.56735710761238 0.6371947901350659 1.3042575608001021 5.71791678938451 9.687194723379386e-06 5.013801970373715 -1.0950455870577283 SSKASLGS(ph)LEGEAEAEASSPK ddPTM_PC-9_AZD4547_30min_R2 1 SSKASLGSLEGEAEAEASSPK 21 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(0.171)S(0.171)KAS(0.119)LGS(0.539)LEGEAEAEASSPK 60.56100000000001 0.0046396 9831900.0 19320.0 17947.0 23283.0 44274.0 45558.0 36584.0 29124.0 41862.0 36614.0 44733.0 True False 25463.358119035736 23748.01677728663 22974.252207158042 34067.31332648124 39233.058088322236 34296.39669669237 31715.97957933608 35393.18979306144 38549.341291037534 43166.911285665505 0.5898814013012644 0.5501439892265969 0.5322190428479217 0.789199697449607 0.9088687821254983 0.7945066180373489 0.7347289540696892 0.8199148083317814 0.8930298727173159 1.0 15.397638247139838 -4.147428255065583 0.22680828909639855 0.9745753934829805 1.1600664965977523e-17 0.7221727147079613 0.07969033443350954 9.611537010607334 0.34370767698921867 0.14942962357038905 2.7532649683284776 7.121504366915148e-05 4.147428255065583 -0.9745753934829805 SSKASLGS(ph)LEGEAEAEASSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSKASLGSLEGEAEAEASSPK 21 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 S(0.16)S(0.16)KAS(0.146)LGS(0.532)LEGEAEAEAS(0.001)S(0.001)PK 51.119 0.017988 9547000.0 29419.0 26810.0 21153.0 38663.0 38627.0 40364.0 35120.0 41973.0 31198.0 34979.0 True False 34399.05564826424 29471.51961888263 21657.367743199222 36496.83745713722 31058.31663623963 38247.240783239045 31793.17935321883 40871.25322406957 31654.211729182673 41320.41580638838 0.8324953894327933 0.713243539391638 0.5241323767088245 0.8832640413917275 0.7516457913145644 0.9256257478736648 0.769430286040428 0.9891297661566764 0.7660671150431343 1.0 15.33456715163229 -5.8071315707774955 24.998880914477784 0.8621384846202194 0.6922848957327161 0.3627317073278321 0.10863530173611824 132.3140110978853 72390.3460136588 0.02941217617845962 0.043625495556707486 1.5590801034174678e-06 5.8071315707774955 -0.16985358888750324 SSLAAVQELGY(ph)S(ph)LGISFLT(ph)NIV ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSLAAVQELGYSLGISFLTNIV 22 0 E7EVF9 E7EVF9 ZBTB21 3 S(0.003)S(0.003)LAAVQELGY(0.922)S(0.93)LGIS(0.237)FLT(0.905)NIV 51.225 0.044798000000000004 0.0 7135.4 5455.6 9346.4 10101.0 7701.0 8618.9 11991.0 8315.0 7334.1 7738.5 True False 8343.282289426032 5997.195913195673 9569.253622419386 9535.073717883843 6192.044332091054 8166.909711293698 10855.125672677883 8096.740060470739 7441.347337745964 9141.428792067707 0.9126890860502845 0.6560457943291775 1.0468006522922233 1.0430616411033813 0.6773606700808168 0.8933953211318969 1.1874648831807564 0.8857193163826342 0.8140245367554627 1.0 13.158203958712628 -7.018814204152511 24.94279655358088 0.9734432608523533 0.8662268740083097 0.09862511303009913 0.15016758168478386 1914.8112178547308 2538542.243279764 0.058639456269372676 0.046230349254891695 9.57603656813499e-08 7.018814204152511 -0.10721638684404367 SSLAETLDSTGS(ph)LDPQR ddPTM_PC-9_AZD4547_30min_R2 1 SSLAETLDSTGSLDPQR 17 0 Q9UGH3-2;Q9UGH3 Q9UGH3-2 SLC23A2 Solute carrier family 23 member 2 1 SSLAET(0.002)LDS(0.082)T(0.235)GS(0.68)LDPQR 70.134 0.015133 4536900.0 5676.6 4678.8 6116.4 6532.6 7331.1 6292.0 4649.2 6781.5 4109.3 6581.4 True False 7481.640719385008 6191.130601079214 6035.292539615234 5026.6099976639 6313.303308997301 5898.560245341908 5062.9697933061825 5733.574998367163 4326.509208697781 6350.987189222253 1.1780279972980414 0.974829647205978 0.950292034891401 0.7914690815617065 0.9940664531194613 0.9287627371303595 0.7971941435967844 0.9027848470702555 0.681234126253624 1.0 12.632765144625743 -1.522878987971776 0.7544787915234699 0.8652816699438769 57.90562067375702 0.4911022784243412 0.09338667103970576 317.16609442271346 1.3439684273031982 0.0337096986658633 30765.15852198922 0.02999998323547404 1.522878987971776 57.040339003813145 SSLET(ph)LEDIEENAPLRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSLETLEDIEENAPLRR 17 1 Q8TDN4-2;Q8TDN4;V9GYB4 Q8TDN4-2 CABLES1 CDK5 and ABL1 enzyme substrate 1 1 S(0.059)S(0.059)LET(0.882)LEDIEENAPLRR 95.954 0.001358 2744200.0 1231.9 685.51 1213.8 2356.2 2537.8 2117.2 1144.2 841.17 1130.4 780.17 True False 1440.4363388659265 753.5629024222385 1242.7415953621337 2224.189752903468 2040.536307749733 2006.170304882412 1035.8130927093678 819.090178793286 1146.9299614933034 921.6086451776778 1.5629587964512024 0.8176604097251696 1.3484482831891669 2.4133777005473562 2.2141028281655672 2.1768136783218224 1.1239185940032848 0.888761388121932 1.2444869820770679 1.0 9.848010439862746 -7.389260386660487 7.106026496958899 1.042610692969855 1.7439624408281058 0.36837619240716146 0.4439749696194884 0.33937642743922997 18.08403789220399 0.21787387157638433 0.14601078308345533 4.080746467396244e-08 7.389260386660487 0.7013517478582507 SSLFS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 SSLFSPR 7 0 Q7RTP6 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 SSLFS(1)PR;SSLFS(1)PR;SSLFS(1)PR;SSLFS(1)PR 101.25 0.011258 26080700.0 72015.4 69323.0 102817.0 107350.0 110484.0 98114.0 91134.0 117928.0 88642.0 92243.0 True False 94914.7991866258 91730.30406484866 101453.57940056556 82602.1160409667 95145.2036926599 91978.9160698467 99244.74945004877 99704.93731585082 93327.43515377035 89013.60064658397 1.0662954705480536 1.0305200935422327 1.1397536855448953 0.9279718541993018 1.0688838896700807 1.0333130600461393 1.1149391635564336 1.1201090236953262 1.0484626447627239 1.0 16.441738166036167 -7.235156089372011 24.70470409917891 1.080886804519829 1.043970166025362 0.035756933008288305 0.05859661295175932 1732.7620461842241 1628694.7798272462 0.021725430728978756 0.0168233267832899 5.818940421919208e-08 7.235156089372011 -0.036916638494467025 SSLFS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSLFSPR 7 0 Q7RTP6 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 SSLFS(1)PR;SSLFS(1)PR;SSLFS(1)PR;SSLFS(1)PR 115.49 0.0082036 22881000.0 84635.0 80188.0 94714.0 84763.0 102346.0 86125.0 103088.0 91976.0 87199.0 72197.0 True False 98962.03388255362 88148.53469597029 96972.34096484509 80014.0039153536 82292.0359969083 81608.45338560268 93322.75834751222 89561.72745662736 88474.12041069947 85285.74458886254 1.160358443953564 1.033567041255352 1.137028719539475 0.9381873172483579 0.964897901678809 0.9568826980289966 1.0942363087453097 1.0501371347389656 1.0373846278438108 1.0 16.380016996477927 -4.338236461810871 1.0024697160376528 1.014983158695168 1.3582348129754267 0.3467230581198182 0.05796566175904083 5.172528079295587 2.282039435817023 0.019808999276466573 2.3631898502903566 4.5894805976740194e-05 4.338236461810871 0.3432516542802586 SSLFS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 SSLFSPR 7 0 Q7RTP6 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 SSLFS(1)PR;SSLFS(1)PR;S(0.004)S(0.001)LFS(0.995)PR;SSLFS(1)PR 98.58200000000001 0.012116 29337000.0 83186.0 86594.0 83642.0 77301.0 87630.0 82903.0 77904.0 77629.0 91602.0 69435.0 True False 81999.7523855561 86393.49691331944 76765.2776274568 82985.97340857673 82475.77568720879 79357.43194633197 81937.48793280039 81235.92673859737 81284.81814817681 81436.7472336782 1.0069134042186434 1.0608662532335449 0.9426368345383827 1.0190236745391257 1.0127587175178936 0.9744671127227154 1.0061488298112564 0.9975340309884358 0.9981343915288582 1.0 16.313392317638403 -5.234146381699466 24.999776970240582 0.9950729576173888 1.0338898191118242 0.3102741036828085 0.02382941224916483 874.8260029066932 801318.8158285376 0.005711648494296942 0.01510430542288453 5.832484835525044e-06 5.234146381699466 0.03881686149443542 SSLGDMFS(ph)PIRDDAVVNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSLGDMFSPIRDDAVVNK 18 1 Q8NHV4-2;Q8NHV4;Q8NHV4-3 Q8NHV4-2 NEDD1 Protein NEDD1 1 S(0.035)S(0.037)LGDMFS(0.929)PIRDDAVVNK 55.763000000000005 0.046372000000000003 0.0 18083.0 15921.0 17198.0 12967.0 20600.0 23131.0 21356.0 20254.0 18643.0 18268.0 True False 21144.094744469978 17501.53166177659 17608.065543778208 12240.501029581212 16563.57787833734 21917.969640201725 19333.005075949368 19722.35396088689 18915.61860590912 21579.843790591567 0.9798075903444876 0.8110128984996152 0.8159496294155296 0.5672191674954503 0.767548553134512 1.0156685957920406 0.8958825311042437 0.9139247787088008 0.8765410347481754 1.0 14.397396801217152 -6.743689465701655 24.979450644136147 0.9322411328537623 0.7788219120640666 0.3541840157015418 0.10199222716398842 292.6165902987813 411798.53438250127 0.035587829346315145 0.035514306203266004 1.804307416627549e-07 6.743689465701655 -0.15341922078969572 SSLGQS(ph)ASETEEDTVSVSK ddPTM_PC-9_AZD4547_30min_R2 2 SSLGQSASETEEDTVSVSK 19 0 E9PPJ0;Q13435;E9PJ04;H0YCG1 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 SSLGQS(0.946)AS(0.054)ETEEDTVSVSK;S(0.205)S(0.205)LGQS(0.53)AS(0.06)ETEEDTVSVSK 259.81 7.444599999999999e-66 16389200.0 59198.0 53956.0 71592.0 72737.0 72925.0 70731.0 60731.0 76804.0 67063.0 67426.0 True False 78021.73260510739 71396.22183291239 70642.64330261813 55968.608425447645 62800.622527128035 66308.17938863307 66135.94134846382 64935.70658034239 70607.81326817196 65065.43626287715 1.1991271723728134 1.0972987492846067 1.0857168930245542 0.8601895513206653 0.9651917536278583 1.0190998969212317 1.0164527458366932 0.998006165946377 1.0851815852413949 1.0 15.98960374514777 -5.199358608883786 2.044558368531799 0.9941160561405862 1.1825247224134314 0.5383198640961213 0.0586376184224409 0.3020881023034354 2.2262187377281606 0.017004864256681344 0.0757456678953351 6.318898670762173e-06 5.199358608883786 0.18840866627284525 SSLGQS(ph)ASETEEDTVSVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSLGQSASETEEDTVSVSK 19 0 E9PPJ0;Q13435;E9PJ04;H0YCG1 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 S(0.006)S(0.008)LGQS(0.973)AS(0.013)ETEEDTVSVSK;SSLGQS(0.995)AS(0.004)ETEEDTVSVSK 257.06 7.722599999999999e-157 5685200.0 25633.0 32173.0 33666.0 28198.0 36374.0 24683.0 28171.0 24916.0 22994.0 22319.4 True False 29972.16062517273 35366.92281605037 34468.72511901599 26618.15747914945 29246.775812943775 23388.580028061875 25502.43893962211 24261.981400684184 23330.243749625828 26365.73053972682 1.1367847585338813 1.3413974159661881 1.307330554223783 1.009574054435635 1.109272347636107 0.8870825707947255 0.9672570574593433 0.9202089570067936 0.8848699911604101 1.0 14.686376350909319 -6.083071102026122 1.390352133981167 0.9351852314432905 1.27134807067992 0.7200588960668114 0.08254654034291906 0.2090128594836543 0.8162673801356928 0.029387251770878687 0.04866458114807359 8.25902722981534e-07 6.083071102026122 0.3361628392366296 SSLGQS(ph)ASETEEDTVSVSK ddPTM_PC-9_Lapatinib_30min_R1 1 SSLGQSASETEEDTVSVSK 19 0 E9PPJ0;Q13435;E9PJ04;H0YCG1 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 SSLGQS(0.491)AS(0.491)ET(0.002)EEDT(0.015)VSVSK 297.7 2.1768999999999995e-121 6721500.0 13346.0 18396.0 19287.0 16574.0 21126.0 18348.0 21094.0 25039.0 19735.0 17481.0 True False 13155.683592643345 18353.405192246868 17701.297309973004 17792.9072492432 19883.410215314067 17563.29881127703 22186.14410626532 26202.403349363525 17512.23648123698 20502.56755803166 0.6416602971996913 0.8951759402961762 0.8633697833147104 0.8678380012103908 0.9698009851222246 0.8566389922415739 1.0821154005940168 1.2780059509716877 0.8541484588049437 1.0 14.323516970806471 -3.6392682748218648 0.34363868414711723 1.0630261741276164 4.2584529230703286e-16 0.4454667854395411 0.11880114642368213 13.652199704323992 0.6995340738646412 0.11081144098527151 7.024468476518639 0.00022947306962957023 3.6392682748218648 -1.063026174127616 SSLGQS(ph)ASETEEDTVSVSKK ddPTM_PC-9_AZD4547_30min_R2 5 SSLGQSASETEEDTVSVSKK 20 1 E9PPJ0;Q13435;E9PJ04;H0YCG1 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 SSLGQS(0.521)AS(0.298)ET(0.181)EEDTVSVSKK;S(0.002)S(0.002)LGQS(0.99)AS(0.005)ET(0.002)EEDTVSVSKK;S(0.004)S(0.004)LGQS(0.476)AS(0.476)ET(0.04)EEDTVSVSKK;S(0.001)S(0.001)LGQS(0.953)AS(0.034)ET(0.011)EEDTVSVSKK;S(0.002)S(0.002)LGQS(0.744)AS(0.218)ET(0.034)EEDT(0.001)VSVSKK 96.052 0.00030741 70213000.0 157663.0 109297.0 162038.0 249964.0 228598.0 203215.0 153302.0 178278.0 146746.0 208843.0 True False 207796.55440587585 144625.11783067355 159889.27024625154 192338.66170530254 196861.1135887068 190507.93392516757 166945.58101467427 150729.23152088773 154502.6939721032 201531.47013686184 1.0310873744173024 0.7176304412033383 0.7933712295041032 0.9543852460098843 0.9768256712215548 0.9453011670871646 0.8283846731297103 0.7479190789335588 0.7666430154416034 1.0 17.620645614755034 -10.58840015685046 4.864851354362269 1.0000037732984393 0.8602488587629786 0.13812487887129787 0.10299490093229942 154240092.49402526 12.040942914953657 6866.568930166849 0.026322830598660873 2.579882004286071e-11 10.58840015685046 -0.13975491453546063 SSLGQS(ph)ASETEEDTVSVSKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SSLGQSASETEEDTVSVSKK 20 1 E9PPJ0;Q13435;E9PJ04;H0YCG1 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 S(0.002)S(0.002)LGQS(0.925)AS(0.066)ET(0.005)EEDTVSVSKK;S(0.022)S(0.007)LGQS(0.932)AS(0.035)ET(0.004)EEDTVSVSKK;S(0.019)S(0.022)LGQS(0.589)AS(0.294)ET(0.076)EEDTVSVSKK;S(0.002)S(0.002)LGQS(0.98)AS(0.014)ET(0.003)EEDTVSVSKK;SSLGQS(0.92)AS(0.077)ET(0.002)EEDTVSVSKK 117.53 0.00020257 54673000.0 139039.0 75303.1 111613.0 156350.0 149892.0 160293.0 139172.0 156961.0 144068.0 129032.0 True False 162575.55655457397 82778.69410714967 114274.27721465939 147590.21639353916 120521.738608725 151886.95290030068 125988.62064197545 152840.94006392665 146174.72195012134 152424.48018325013 1.0665974150551136 0.5430800486091879 0.7497107884329 0.9682842035354227 0.7906980457721062 0.9964734845590209 0.8265642139012542 1.002732237500012 0.9589976739588345 1.0 17.21773510038313 -6.635482409867805 0.7265126435370757 0.9748712400966322 0.779274458253038 0.16913731147635214 0.13887979509298035 1.1484409448395205 1.3476664560643097 0.09385431711022789 0.10760574345612142 2.3148219408315208e-07 6.635482409867805 -0.1955967818435942 SSLGQS(ph)ASETEEDTVSVSKK ddPTM_PC-9_Lapatinib_30min_R1 5 SSLGQSASETEEDTVSVSKK 20 1 E9PPJ0;Q13435;E9PJ04;H0YCG1 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 S(0.003)S(0.001)LGQS(0.887)AS(0.041)ET(0.027)EEDT(0.039)VS(0.001)VSKK;SSLGQS(0.495)AS(0.495)ET(0.009)EEDTVSVSKK;S(0.018)S(0.007)LGQS(0.96)AS(0.015)ET(0.001)EEDTVSVSKK;S(0.005)S(0.005)LGQS(0.384)AS(0.379)ET(0.174)EEDT(0.038)VS(0.013)VS(0.002)KK;S(0.001)S(0.001)LGQS(0.984)AS(0.015)ETEEDTVSVSKK 141.15 9.679899999999999e-05 157911000.0 289447.0 165931.0 202451.0 207609.0 179977.0 183047.0 132863.0 142594.0 199502.0 154770.0 True False 285319.43270192086 165546.79696427 185806.26026345932 222877.25842332124 169391.1067083963 175218.50651339782 139741.99603634802 149219.43780499036 177031.98391080528 181521.7882819378 1.5718192036471434 0.9119940836366398 1.0236030727885235 1.2278264804065864 0.9331723112230459 0.96527534337228 0.7698359373768519 0.8220469796894257 0.9752657550720082 1.0 17.469783201499183 -6.371965478247469 4.607406652001078 0.8927526592760837 1.1524138563228428 0.3663885933260921 0.17331489844811515 0.2727694287712894 9.269498386741057 0.05436626389362274 0.06195153179907859 4.2465331798817616e-07 6.371965478247469 0.25966119704675905 SSLGQSAS(ph)ETEEDTVSVSK ddPTM_PC-9_AZD4547_30min_R2 2 SSLGQSASETEEDTVSVSK 19 0 E9PPJ0;Q13435;E9PJ04;H0YCG1 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 SSLGQSAS(0.5)ET(0.5)EEDTVSVSK;SSLGQS(0.028)AS(0.969)ET(0.003)EEDTVSVSK 309.09 1.9512999999999996e-138 17651000.0 49310.0 51965.0 63866.0 69577.0 68108.0 68717.0 58533.0 68859.0 63331.0 52896.0 True False 64989.55428828425 68761.67001903936 63019.09511069692 53537.09760393434 58652.37982965567 64420.115127012024 63742.32360655403 58218.42377240495 66678.54736720103 51044.127140289354 1.2732033620570564 1.3471024752770329 1.234600308425211 1.0488395159896322 1.1490524594231153 1.2620475407476395 1.2487690000333445 1.1405508730200795 1.3062922436491495 1.0 15.63945736155408 -11.85359014273689 1.991407788431357 6.91232685996124e-05 1.2194804358732856 0.3903855931354697 0.08361612367912633 1676445.9300650095 226505.776560343 7517466.016768839 0.02273288919374791 1.4009087802824291e-12 11.85359014273689 1.219411312604686 SSLGQSAS(ph)ETEEDTVSVSK ddPTM_PC-9_Lapatinib_30min_R1 3 SSLGQSASETEEDTVSVSK 19 0 E9PPJ0;Q13435;E9PJ04;H0YCG1 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 SSLGQS(0.12)AS(0.871)ET(0.006)EEDT(0.002)VSVSK;SSLGQSAS(0.977)ET(0.019)EEDT(0.003)VSVSK;SSLGQS(0.001)AS(0.957)ET(0.001)EEDT(0.04)VSVSK 178.07 8.2345e-09 23390200.0 83255.0 110228.0 125839.0 105339.0 123130.0 123922.0 128863.0 132095.0 110858.0 96183.0 True False 82067.76843290278 109972.77383838818 115493.00317258753 113085.9814606025 115887.73548289409 118622.14493629128 135534.89560849857 138232.615936506 98372.00465350742 112808.10339420843 0.7274988760879756 0.9748659052806501 1.023800593198493 1.0024632810767418 1.027299741738622 1.0515392189669712 1.201464181477028 1.225378423865983 0.872029594449842 1.0 16.783511179644584 -4.1453854406837065 0.9481895181015597 1.0731786508914374 2.8418022084226373e-15 0.4998043378294367 0.09632344857272389 4.959806056514544 1.5067877506399092 0.032441591453751785 7.3018471108504315 7.155081077549065e-05 4.1453854406837065 -1.0731786508914345 SSLGQSAS(ph)ETEEDTVSVSKK ddPTM_PC-9_AZD4547_30min_R2 3 SSLGQSASETEEDTVSVSKK 20 1 E9PPJ0;Q13435;E9PJ04;H0YCG1 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 S(0.011)S(0.011)LGQS(0.437)AS(0.498)ET(0.042)EEDT(0.001)VSVSKK;SSLGQS(0.04)AS(0.899)ET(0.061)EEDTVSVSKK;SSLGQS(0.081)AS(0.903)ET(0.016)EEDTVSVSKK 121.38 4.6338e-06 72990000.0 59990.0 49965.0 78880.0 123096.0 104207.0 82834.0 67373.0 77572.0 65724.0 72541.0 True False 79065.57213048422 66115.20913117104 77833.99966072357 94718.11901424166 89739.65679375271 77654.37688535466 73369.06648120502 65585.02982722672 69198.03646179469 70001.36166976209 1.1294862020468028 0.9444846150718562 1.1118926518588692 1.3530896650422768 1.2819701596250064 1.1093266621254654 1.0481091328955914 0.9369107723451178 0.9885241488336018 1.0 16.09509536525143 -7.3541908993279455 2.602002728481589 0.9745882988144594 1.1605177994464675 0.3865809605739048 0.10308745435027977 0.35193399568950506 4.646657853201659 0.05786273961637013 0.036072923723497685 4.423938701070711e-08 7.3541908993279455 0.18592950063200808 SSLGQSAS(ph)ETEEDTVSVSKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSLGQSASETEEDTVSVSKK 20 1 E9PPJ0;Q13435;E9PJ04;H0YCG1 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 S(0.001)S(0.001)LGQS(0.067)AS(0.891)ET(0.04)EEDTVSVSKK;SSLGQS(0.223)AS(0.619)ET(0.156)EEDTVSVSKK 162.41 1.0761e-06 24306000.0 58009.0 36191.6 48195.0 69236.0 70166.0 72746.0 64821.0 58731.0 64843.0 50567.0 True False 67828.77797002492 39784.4628660482 49344.15158055533 65356.93138614059 56417.47599084543 68931.07169798599 58680.68561660017 57189.373480638256 65791.20620409613 59734.39681184823 1.135506200617919 0.6660226768734527 0.8260592592234561 1.0941255771277352 0.9444721802171961 1.1539594501155759 0.9823600596727033 0.9573943411661743 1.1013956734396377 1.0 15.866274296292898 -5.754533033709095 24.988214247320737 1.030804497563414 0.8548786712433517 0.24597297502680393 0.12471844471135685 198.05620884515847 716588.9544366411 0.03255701849040498 0.05485237737768185 1.7598148020472869e-06 5.754533033709095 -0.17592582632006237 SSLGQSAS(ph)ETEEDTVSVSKK ddPTM_PC-9_Lapatinib_30min_R1 2 SSLGQSASETEEDTVSVSKK 20 1 E9PPJ0;Q13435;E9PJ04;H0YCG1 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 SSLGQS(0.039)AS(0.959)ET(0.002)EEDTVSVSKK;S(0.001)S(0.001)LGQS(0.101)AS(0.42)ET(0.223)EEDT(0.231)VS(0.021)VS(0.002)KK 129.32 1.4156e-05 43129500.0 66261.0 35257.0 46615.0 39741.0 43041.0 43720.0 31963.0 31303.0 43436.0 30446.0 True False 65316.105989220785 35175.364582683615 42782.49463910362 42663.6857120897 40509.41300186181 41850.19751629778 33617.887743839885 32757.45165721982 38543.780278642495 35708.55053325505 1.8291447010259485 0.9850683955912776 1.198102247226772 1.1947750629742697 1.1344457390992602 1.1719937351509988 0.941452039968182 0.9173559600721709 1.079399183194149 1.0 15.1239819533803 -4.75723392662685 24.999940304811403 1.0758094092843669 1.829145805033184 0.8399754171718913 0.09947432237457993 51.92292516381016 308623.0127397037 0.027205059582500565 0.2057890809471166 1.7489044120617622e-05 4.75723392662685 0.7533363957488171 SSLGQSASET(ph)EEDTVSVSKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSLGQSASETEEDTVSVSKK 20 1 E9PPJ0;Q13435;E9PJ04;H0YCG1 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 S(0.001)S(0.001)LGQS(0.027)AS(0.169)ET(0.791)EEDT(0.011)VS(0.001)VSKK 67.532 0.0046665 12374000.0 15048.0 8397.7 7581.5 14146.0 15992.0 15209.0 8906.6 13115.0 15267.0 10238.0 True False 17595.32918845237 9231.368157534152 7762.271712998864 13353.445481950794 12858.482399532551 14411.41326608569 8062.902369800084 12770.745146491134 15490.25099267362 12094.068356036596 1.4548726425603418 0.7632971706271559 0.6418246932699391 1.1041318015443162 1.063205698942028 1.1916100390562472 0.6666823877984444 1.0559511299699893 1.280813911138667 1.0 13.56201201783018 SSLGQSASET(ph)EEDTVSVSKK ddPTM_PC-9_Lapatinib_30min_R1 1 SSLGQSASETEEDTVSVSKK 20 1 E9PPJ0;Q13435;E9PJ04;H0YCG1 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 S(0.001)S(0.005)LGQS(0.207)AS(0.144)ET(0.64)EEDT(0.003)VSVSKK 81.65 0.0010307 55741000.0 16853.0 15763.0 11758.0 13124.0 8604.7 12413.0 9059.5 8864.6 10415.0 8675.3 True False 16612.673129538307 15726.501741975833 10791.30262719254 14089.182740380596 8098.588463491098 11882.124926116287 9528.556581526062 9276.481677813337 9241.953025187904 10174.81404588937 1.632724986875788 1.5456303841080365 1.060589665670817 1.3847115708294082 0.7959446164780704 1.1677977477059318 0.9364845921066836 0.9117101930291336 0.9083166516366613 1.0 13.312714807699477 -4.622510754179095 0.5655433173818587 0.9350908347757272 2.3057275200425456 0.7214362005012847 0.1454204600927888 2.283229178854827 0.4883192316943033 0.07358840992489935 2.140468781355703 2.385004736262857e-05 4.622510754179095 1.3706366852668184 SSLGQSASETEEDT(ph)VSVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSLGQSASETEEDTVSVSK 19 0 E9PPJ0;Q13435;E9PJ04;H0YCG1 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 SSLGQS(0.02)AS(0.223)ET(0.006)EEDT(0.739)VS(0.012)VSK 144.4 0.00051889 4647900.0 10287.0 18907.0 18175.0 13719.0 16769.0 11214.0 14902.0 14598.0 12380.0 12875.0 True False 12028.385922488662 20783.962007990056 18608.360929071343 12950.368907598113 13483.234827273727 10625.918098881248 13490.374678862961 14214.817967859519 12561.034079341032 15209.135581556078 0.7908658488833074 1.366544593973802 1.2234989180869333 0.8514861898728063 0.8865221008105596 0.6986536507549556 0.8869915457406116 0.9346236603411995 0.8258874419249465 1.0 13.892650538684103 -5.769148169334231 24.96671510508841 0.8608034894670075 1.1509272761745235 0.36871936697155316 0.15335338329246403 153.0417879509253 495662.92786019744 0.04190496160127304 0.06349433768166184 1.7015778777740721e-06 5.769148169334231 0.29012378670751604 SSLGQSASETEEDT(ph)VSVSK ddPTM_PC-9_Lapatinib_30min_R1 1 SSLGQSASETEEDTVSVSK 19 0 E9PPJ0;Q13435;E9PJ04;H0YCG1 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 SSLGQSAS(0.197)ET(0.001)EEDT(0.793)VS(0.009)VSK 197.94 1.5244e-14 14857000.0 19213.0 32132.0 31474.0 27892.0 31402.0 29494.0 31197.0 36265.0 33725.0 25814.0 True False 18939.019096767322 32057.60032818418 28886.329213153425 29943.27072498441 29554.996098707386 28232.610373872063 32812.22801190666 37950.00429189142 29926.53536000593 30275.915505007113 0.6255473626762875 1.058848255897742 0.9541025838963029 0.9890128911223943 0.9761883532083283 0.9325105418927093 1.0837732720743023 1.2534717335175263 0.9884601294734291 1.0 14.885882965383633 -4.7587772776678765 24.999990705056643 1.028067600844055 0.6255468280884091 0.6552099675692515 0.08719682367754257 48.66636332057728 456939.4489239266 0.02350044311802076 0.1570104758482183 1.7427003657037686e-05 4.7587772776678765 -0.4025207727556459 SSLGSLQT(ph)PEAVTTR ddPTM_PC-9_AZD4547_30min_R2 1 SSLGSLQTPEAVTTR 15 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 S(0.006)SLGS(0.013)LQT(0.949)PEAVT(0.024)T(0.009)R 75.877 0.035506 14869000.0 16981.0 14524.0 20432.0 25491.0 17122.0 20385.0 9554.3 18908.0 15902.0 19949.0 True False 22380.604773258063 19218.598967699945 20161.058329968357 19614.443782024064 14744.905847233269 19110.32272747851 10404.614190868375 15986.203062615406 16742.547255423575 19250.591582003024 1.1625930911225202 0.9983380970830534 1.0472955204564471 1.0189008321365665 0.7659455962391293 0.9927135301828517 0.540482828620988 0.8304265868671056 0.8697159868622341 1.0 14.232615160905459 -6.166080673422856 4.538915098351521 0.8182032211083997 1.0579057183612666 0.4254528223685704 0.1270415651220094 0.2158103654949848 7.565145344832703 0.03751393282158263 0.049011984935496175 6.822119564372855e-07 6.166080673422856 0.23970249725286685 SSLGSLQT(ph)PEAVTTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSLGSLQTPEAVTTR 15 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 SSLGS(0.028)LQT(0.631)PEAVT(0.026)T(0.315)R;S(0.002)SLGSLQT(0.998)PEAVTTR;SSLGS(0.004)LQT(0.992)PEAVT(0.004)T(0.001)R;SSLGSLQT(0.999)PEAVTTR 148.18 1.8310999999999998e-05 22890100.0 86850.0 81834.0 71272.0 65988.9 77386.0 52561.0 62618.0 52211.1 46116.8 38839.3 True False 101551.98963430939 89957.93869793527 72971.39478056523 62291.7558719003 62222.76882004915 49804.6086316477 56686.369724938966 50840.61394723318 46791.17095558598 45880.55763827039 2.2133992013558643 1.9606984598395243 1.5904644262583578 1.357693957493246 1.356190334708295 1.0855275348725086 1.235520504608146 1.1081080214427355 1.0198474771055532 1.0 15.485595305713089 -3.8036721029504825 0.41517113528899924 1.0276042208164191 4.669464063323859 0.9732098972909383 0.0640460480676892 1.6744946132185996 0.12093280962312783 0.04633172487447256 3.564570716073931 0.0001571548893000793 3.8036721029504825 3.6418598425074395 up SSLGSLQT(ph)PEAVTTR ddPTM_PC-9_Lapatinib_30min_R1 2 SSLGSLQTPEAVTTR 15 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 SSLGS(0.003)LQT(0.887)PEAVT(0.084)T(0.026)R;SS(0.001)LGS(0.437)LQT(0.563)PEAVTTR 200.71 8.8994e-10 23994000.0 40548.0 38958.0 42704.0 34063.0 33727.0 31880.0 31558.0 29070.6 36113.0 28331.0 True False 39969.778084407495 38867.795144572374 39193.04196220705 36568.106650836955 31743.244169833255 30516.566715909714 33191.918825520086 30421.326203442917 32045.573653251133 33227.97560131543 1.2028953723808913 1.1697310606859141 1.1795194035430636 1.100521653488553 0.9553168255178507 0.9183998171318514 0.9989148669113047 0.9155335422311612 0.964415468391716 1.0 15.020110779744336 -6.091847541081682 2.5422258567813496 0.9532410309127575 1.1828596967029612 0.9298439164081675 0.028148781705312712 0.06512192931317168 0.8256276903237728 0.00861971782047039 0.012238371228288032 8.093799818571799e-07 6.091847541081682 0.22961866579020374 SSLIILK ddPTM_PC-9_Lapatinib_30min_R1 1 SSLIILK 7 0 P28066;P28066-2 P28066 PSMA5 Proteasome subunit alpha type-5 0 108.09 0.045208 4242500.0 36504.0 29666.0 34841.0 28608.0 34712.0 32552.0 36931.0 34266.0 29878.0 32432.0 False True 35983.446265986284 29597.3101996736 31976.50747014928 30711.927753490396 32670.308406417756 31159.82684241824 38843.1064752292 35858.12345418311 26512.82501071186 38037.827987076394 0.9459910875618844 0.7781020043975562 0.8406501938284571 0.8074048750608205 0.8588899560068917 0.8191799713959745 1.021170464528795 0.9426963986052553 0.6970120644038815 1.0 15.215147248204891 SSLNSS(ph)PWSGLMALGNSR ddPTM_PC-9_AZD4547_30min_R2 1 SSLNSSPWSGLMALGNSR 18 0 Q8TCJ2 Q8TCJ2 STT3B Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B 1 SSLNS(0.078)S(0.806)PWS(0.117)GLMALGNSR 167.9 1.0677e-07 2758900.0 12528.0 13461.0 21232.0 17357.0 17994.0 11142.0 16987.0 24627.0 13857.0 11036.0 True False 16511.643401411995 17812.005005797917 20950.44980725764 13355.611812976807 15495.84369904891 10445.28897863947 18498.810091820567 20821.463022161497 14589.45273037382 10649.632999096972 1.5504424803006909 1.6725463691855178 1.967246177312788 1.254091273765893 1.4550589396238227 0.9808121068139316 1.7370373320272314 1.9551343247158883 1.3699488735068075 1.0 13.378516093615039 -5.76923262042847 24.99569260228974 1.432678819387399 1.7243251598386424 0.2043436756944842 0.2975306538145832 324.72939353092863 1041524.7550717568 0.08738398273489331 0.13235306475419367 1.7012470282032346e-06 5.76923262042847 0.2916463404512435 SSLNSS(ph)PWSGLMALGNSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSLNSSPWSGLMALGNSR 18 0 Q8TCJ2 Q8TCJ2 STT3B Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B 1 S(0.046)S(0.138)LNS(0.306)S(0.509)PWSGLMALGNSR 89.87700000000001 0.0013959 2750700.0 28533.0 32193.0 18579.0 18079.0 11155.0 18711.0 16234.0 14701.0 18717.0 7142.7 True False 28126.114187688647 32118.459086432013 17051.506337013958 19408.589969776043 10498.884831573807 17910.774147471355 17074.517086427953 15384.062128639056 16608.894361252223 8377.3061779505 3.357417478869045 3.8339841476690255 2.0354402686026205 2.3168056123889142 1.2532530873954935 2.13801116576274 2.038187064401318 1.8363972620614841 1.9826056262534233 1.0 13.032270687477164 -5.311479463949526 5.20444752868817 1.860031697178678 3.599262379601017 0.7607365956291559 0.3971351211171373 0.08243210875929502 5.173307054106219 0.099310173239792 0.22001897524858244 4.881131816235897e-06 5.311479463949526 1.739230682422339 SSLNSSPWS(ph)GLMALGNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSLNSSPWSGLMALGNSR 18 0 Q8TCJ2 Q8TCJ2 STT3B Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B 1 SSLNS(0.011)S(0.051)PWS(0.917)GLMALGNS(0.021)R 82.705 0.0022468 3863800.0 23573.0 19503.0 21777.0 16793.0 27106.0 15030.0 15032.0 11866.0 12999.0 12607.0 True False 27563.443312027346 21439.128949163285 22296.2462697324 15852.14265364057 21794.773882049118 14241.800341197182 13608.06013774446 11554.53007306625 13189.085783308086 14892.549303042915 1.8508210213811718 1.4395875758344974 1.497141007629683 1.0644344585383771 1.463468304757998 0.9563037228479903 0.9137495442075856 0.7758597831672361 0.8856163921252375 1.0 13.862303114802678 -5.180326508436576 0.43011819106669885 0.8353635206035601 2.2143656736536848 0.7778114500715194 0.15738172647612675 1.7324635502720096 0.323491439824015 0.12565113445714143 1.183488901000119 6.6019691645418444e-06 5.180326508436576 1.3790021530501246 SSLPRPS(ph)SILPPR ddPTM_PC-9_AZD4547_30min_R2 1 SSLPRPSSILPPR 13 1 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4;H7BZB9 A0A669KB77 MAP2 Microtubule-associated protein 2 1 S(0.217)S(0.044)LPRPS(0.37)S(0.37)ILPPR 52.79 0.042741 13695000.0 19151.0 8299.7 31799.0 34577.0 22085.0 21819.0 23376.0 25317.0 19837.0 14817.0 True False 25240.619634454117 10982.415715520461 31377.324482902506 26605.80685932473 19018.87896484912 20454.654480787507 25456.418714687545 21404.839376784115 20885.543321961854 14298.2613399438 1.7652929285843735 0.7680944874633008 2.1944853109689935 1.8607721754951017 1.3301532621814474 1.430569353467133 1.7803856083936709 1.4970239295450063 1.4607051043063355 1.0 13.803552106361366 -8.840872864594157 1.6356556579152677 1.0004925475000372 1.5760384966603709 0.19043959540201483 0.3578274057901378 2.2375153265300565 9.041716644946149 0.34182634514831534 0.09752838075341197 1.442537578301413e-09 8.840872864594157 0.5755459491603336 SSLS(ph)GDEEDELFK ddPTM_PC-9_AZD4547_30min_R2 3 SSLSGDEEDELFK 13 0 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 1 SS(0.007)LS(0.993)GDEEDELFK;S(0.004)S(0.004)LS(0.992)GDEEDELFK;S(0.001)S(0.096)LS(0.902)GDEEDELFK 174.39 0.00017996 24515000.0 69948.8 71281.6 74456.0 85924.2 88880.0 81555.0 67541.7 82721.9 72697.3 73855.0 True False 92191.0633745761 94321.98321233816 73468.66479131389 66115.70320565657 76540.54618047507 76455.35295754283 73552.78045438966 69939.13111515575 76539.93086352051 71269.35892971259 1.2935581961035592 1.3234577191210684 1.0308590661488943 0.9276876374159803 1.0739614797989279 1.0727661102290085 1.032039316179749 0.9813352072400603 1.0739528461173038 1.0 16.12099432688418 -5.264205313046479 24.353198616907775 1.0237712294131014 1.308507984804149 0.8684863247766106 0.044273342708250174 49.65137083193648 437172.2150535581 0.011764342554927676 0.02638104455401213 5.4424529963610335e-06 5.264205313046479 0.2847367553910476 SSLS(ph)GDEEDELFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSLSGDEEDELFK 13 0 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 1 S(0.002)S(0.007)LS(0.991)GDEEDELFK;SS(0.001)LS(0.999)GDEEDELFK 174.65 0.00017636 15268700.0 37500.8 40272.5 34763.4 39271.2 43871.0 33132.8 36818.0 34862.6 30023.5 25568.0 True False 43848.94476543822 44270.48764831968 35592.29129692868 37070.961982948225 35274.792480608594 31395.25764103911 33330.33250076341 33947.49368997804 30462.536888618386 30203.27600382336 1.4517943272076672 1.4657511868154827 1.178424860019262 1.2273821547786903 1.1679127944976313 1.0394653095599582 1.1035336860989584 1.1239672704934625 1.0085838663581463 1.0 14.882417419766774 -3.7769617424127637 0.3747067961383741 1.0264259030995133 2.384937504021263 0.8737618825285267 0.05598988409939287 4.086859564914278 0.253834725957662 0.04590588256606314 2.9028001125024665 0.00016712378294230957 3.7769617424127637 1.3585116009217495 SSLS(ph)GDEEDELFK ddPTM_PC-9_Lapatinib_30min_R1 2 SSLSGDEEDELFK 13 0 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 1 S(0.004)S(0.014)LS(0.982)GDEEDELFK;SSLS(1)GDEEDELFK 167.55 2.6315e-18 0.0 10622.0 13530.0 14147.9 10534.599999999999 13238.4 10812.7 11539.1 11200.6 12841.1 8649.8 True False 10470.528332163769 13498.672116280724 12984.714274473323 11309.349626395406 12459.7433396958 10350.266026634785 12136.538136750072 11721.0207658006 11394.80009522231 10144.906404865978 1.0320970854045146 1.3305861658621239 1.2799245016440208 1.1147810709195805 1.2281772588576585 1.020242633453011 1.1963183939211912 1.1553601677565644 1.1232040632486096 1.0 13.308467934653033 -6.3182461317278165 1.6770062406118273 1.1183827225523066 1.2158168835578196 0.14526853210361024 0.09824997663658445 0.7152297986012489 3.9889102046390033 0.03511765798869901 0.04501360150256126 4.805669151258965e-07 6.3182461317278165 0.09743416100551294 SSLS(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSLSPGR 7 0 Q9BUQ8;F8W1J5;F8VVA2 Q9BUQ8 DDX23 Probable ATP-dependent RNA helicase DDX23 1 S(0.003)S(0.009)LS(0.988)PGR 75.043 0.033296 162520000.0 203580.0 228200.0 189640.0 227130.0 240130.0 226130.0 208390.0 222630.0 189560.0 144390.0 True False 238042.07311171776 250854.18787874034 194161.73681370466 214404.64246539545 193078.25028762795 214271.3447208863 188649.79058705262 216786.19839598384 192331.95638771297 170566.76400938933 1.395594707410959 1.4707096621996731 1.1383327692317389 1.2570130160503774 1.1319804969566019 1.2562315171148533 1.1060172928922298 1.2709756185797734 1.1276051199348867 1.0 17.379977030412192 -1.5228787452803376 0.3292163073703061 1.1218949779764698 4.518930160716637 0.5565132526020349 0.09011447627084887 43.803011973135234 0.6237316137721387 0.07900240711581408 90.46310489377089 0.029999999999999995 1.5228787452803376 3.397035182740167 SSLS(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 1 SSLSPGR 7 0 Q9BUQ8;F8W1J5;F8VVA2 Q9BUQ8 DDX23 Probable ATP-dependent RNA helicase DDX23 1 S(0.001)S(0.023)LS(0.977)PGR 71.692 0.040763 170390000.0 81931.0 72554.0 85296.0 76646.0 105770.0 100870.0 75115.0 83720.0 83143.0 75134.0 True False 80762.64891569462 72386.00567070438 78283.29213208146 82282.80252356062 99548.81655182087 96556.02523945463 79004.0871594823 87609.93683488602 73778.55980539588 88120.81179023812 0.9164991478737304 0.8214405223934079 0.8883632656315765 0.9337499377493907 1.1296856500685202 1.0957232834996526 0.896542888728066 0.9942025618582795 0.8372433061671926 1.0 16.427195165105225 -5.910034053531414 3.944328504938994 0.9950578698272978 0.8705534895895686 0.28301075487614413 0.08263655529777975 0.2926726933092743 8.670978206035569 0.025348667895311844 0.03883100012893621 1.2301723078005172e-06 5.910034053531414 -0.12450438023772925 SSLS(ph)VR ddPTM_PC-9_Lapatinib_30min_R1 1 SSLSVR 6 0 P25100 REV__M0R1G2 ADRA1D Alpha-1D adrenergic receptor 1 SSLS(1)VR 85.359 0.041513 3487800.0 37293.0 37089.0 45955.0 33514.0 36987.0 32596.0 27217.0 28185.0 38667.0 25652.0 True False 36761.19498130141 37003.12269924138 42176.75729142995 35978.73135942661 34811.49737923986 31201.94506498723 28626.16308619621 29494.577994401192 34311.91527843882 30085.91402085853 1.2218739625399087 1.2299151913279802 1.4018772127776757 1.1958663225083537 1.1570696291661635 1.0370948026825761 0.9514805854443952 0.9803450868719705 1.1404644464067273 1.0 14.876800566575787 -6.489132361457392 1.864488815222848 1.013783168941729 1.2758046150895752 0.7367650687783549 0.06831529504503961 0.17662092891813946 1.2325121416522917 0.02616771245037538 0.029143596191741984 3.2424078228484355e-07 6.489132361457392 0.2620214461478463 SSLSNNS(ph)LK ddPTM_PC-9_AZD4547_30min_R2 1 SSLSNNSLK 9 0 Q9ULJ7-2;Q9ULJ7 Q9ULJ7-2 ANKRD50 Ankyrin repeat domain-containing protein 50 1 SSLS(0.002)NNS(0.998)LK 84.65799999999999 0.013037 7026800.0 41817.0 32600.0 41523.0 59244.0 59461.0 48574.0 50839.0 52150.0 48565.0 57229.0 True False 55113.936152366296 43137.31247225408 40972.377889353775 45586.211110675686 51205.8665215709 45536.660101277455 55363.572511806975 44091.415787782615 51132.04675258746 55225.43012915191 0.9979811116631437 0.7811132004109669 0.7419114309030187 0.825456877457837 0.9272153499179502 0.8245596275988074 1.0025014270116503 0.7983897216313038 0.9258786510672433 1.0 15.753045129757936 -6.2496305528064 23.37647090670446 0.9030542545856037 0.8258865899953126 0.1454952363839871 0.0872824120937799 613.5247820842028 1214514.532892937 0.02527375198191439 0.03231918731670547 5.628199032640454e-07 6.2496305528064 -0.07716766459029112 SSLSNNS(ph)LK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSLSNNSLK 9 0 Q9ULJ7-2;Q9ULJ7 Q9ULJ7-2 ANKRD50 Ankyrin repeat domain-containing protein 50 1 SSLS(0.005)NNS(0.995)LK 89.561 0.018622 0.0 31421.0 29745.0 26267.0 40682.0 34875.0 34677.0 36566.0 42038.0 32016.0 26593.0 True False 36739.954706961835 32697.887022143357 26893.304898152244 38402.719432823535 28041.49410228224 32858.47707463038 33102.20376508541 40934.54704294279 32484.173431678708 31414.10038992783 1.1695370630044084 1.040866573171936 0.8560902449644852 1.2224675848153983 0.8926403670395433 1.04597861045754 1.053737122954469 1.3030628455006612 1.0340634628548513 1.0 14.939124645561424 -7.5470933976494035 24.981749017007154 1.1368178964458238 1.0331050121696024 0.053665636199930034 0.1275450499293082 490.8288218460808 506371.219699179 0.057125203753099686 0.032983366506433714 2.8373087824478697e-08 7.5470933976494035 -0.10371288427622138 SSLSSAQADFNQLAELDR ddPTM_PC-9_Lapatinib_30min_R1 1 SSLSSAQADFNQLAELDR 18 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 210.37 6.0418e-20 2493200.0 9578.2 12177.0 10480.0 12771.0 14110.0 13983.0 11765.0 11445.0 15252.0 12021.0 False True 9441.613111573248 12148.804904652656 9618.374853969874 13710.221942807113 13280.077541327335 13384.979685965049 12374.134133412888 11976.776482026662 13534.159149319808 14098.81383302435 0.669674287737433 0.8616898590572144 0.6822116362328495 0.9724379728096687 0.9419287110679305 0.9493692054159016 0.877671999925862 0.8494882352423766 0.9599501993293987 1.0 13.783286169889948 -5.766070696061339 24.999943754069005 0.9279582234734347 0.7502417121818311 0.6646829807705931 0.06408723218474179 71.57758172613697 386380.1462402893 0.01745516751477321 0.026886720403153624 1.713678325908899e-06 5.766070696061339 -0.1777165112916036 SSLSTS(ph)SPESAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSLSTSSPESAR 12 0 Q8N7B6;D6RF51;D6RGK2;D6RAM4;D6RC23;D6R9D1;D6REJ6;D6RF67;D6RF08;D6RBZ2;D6RDH3;D6REQ4;D6R9F1;D6RB63;D6RC13;Q8N7B6-2;Q8N7B6-3;Q8N7B6-4;D6R9N9 Q8N7B6 PACRGL PACRG-like protein 1 SSLS(0.019)T(0.101)S(0.539)S(0.34)PES(0.001)AR 112.64 0.00092878 7379200.0 13793.0 13702.0 26301.0 23701.0 30572.0 27641.0 22279.0 23717.0 22894.0 13013.0 True False 16127.88247583223 15062.244006636685 26928.11558709794 22373.109809678743 24581.6360629383 26191.45730080048 20168.57183400806 23094.453880238678 23228.78143880723 15372.153889148676 1.0491621793623227 0.9798395277105079 1.7517464228683468 1.4554310326981632 1.5991016119276995 1.7038248178929067 1.3120199016642171 1.5023564067063648 1.5110947760680828 1.0 13.908031703815883 -5.244818190661244 24.59538577583259 1.50283780915808 1.0145007207048005 0.45710627889733735 0.20139365076594254 519.9595133405313 769411.9927468424 0.04784658236292716 0.12577426223588145 5.690911204376593e-06 5.244818190661244 -0.4883370884532796 SSLSTSS(ph)PESAR ddPTM_PC-9_AZD4547_30min_R2 2 SSLSTSSPESAR 12 0 Q8N7B6;D6RF51;D6RGK2;D6RAM4;D6RC23;D6R9D1;D6REJ6;D6RF67;D6RF08;D6RBZ2;D6RDH3;D6REQ4;D6R9F1;D6RB63;D6RC13;Q8N7B6-2;Q8N7B6-3;Q8N7B6-4;D6R9N9 Q8N7B6 PACRGL PACRG-like protein 1 SSLS(0.006)T(0.052)S(0.325)S(0.618)PESAR;SSLS(0.002)T(0.011)S(0.067)S(0.92)PESAR 171.62 8.5614e-05 19248600.0 50384.0 50860.0 108397.0 158977.0 128303.0 97632.0 81222.0 112063.0 79516.0 98158.0 True False 66405.06394769643 67299.5003784921 106959.58495465842 122327.30882016549 110490.34312098892 91527.05560604273 88450.60065213696 94746.23830155861 83719.0534248687 94721.51829696982 0.7010557383540246 0.7104985391756018 1.1292004908464406 1.2914415965825876 1.166475634127621 0.966275216567878 0.9337962718759178 1.0002609755949148 0.8838440824226833 1.0 16.531404585748085 -5.252798054719585 24.023019739016743 1.0525761609781923 0.7057770322145743 0.5850216700295923 0.11466203936106434 283.5731655902091 788329.4283321069 0.033546185967684355 0.08562983583742023 5.587299416368674e-06 5.252798054719585 -0.34679912876361796 SSLSTSS(ph)PESAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSLSTSSPESAR 12 0 Q8N7B6;D6RF51;D6RGK2;D6RAM4;D6RC23;D6R9D1;D6REJ6;D6RF67;D6RF08;D6RBZ2;D6RDH3;D6REQ4;D6R9F1;D6RB63;D6RC13;Q8N7B6-2;Q8N7B6-3;Q8N7B6-4;D6R9N9 Q8N7B6 PACRGL PACRG-like protein 1 SSLS(0.066)T(0.066)S(0.157)S(0.698)PES(0.012)AR 77.74 0.017235 6582400.0 16120.0 13573.0 27353.0 20902.0 28070.0 27602.0 23149.0 24492.0 25384.0 15324.0 True False 18848.797615487245 14920.437739167985 28005.199256830154 19730.92870519831 22569.885002181014 26154.502529456062 20956.159135753507 23849.110951419047 25755.192978190033 18102.11989528274 1.0412480816900944 0.8242370410471165 1.5470673832034487 1.0899788985675662 1.2468089446287745 1.4448309192931434 1.157663260269009 1.3174761348052901 1.4227722016636084 1.0 14.143871037262677 -5.244932890695194 24.998814775202394 1.2834482718895834 0.9327425337957094 0.41006877389479734 0.16570849475380067 736.1152230034687 1114830.8989776855 0.039357667715090174 0.10346659534745951 5.689408395693426e-06 5.244932890695194 -0.35070573809387406 SSLSTSS(ph)PESAR ddPTM_PC-9_Lapatinib_30min_R1 2 SSLSTSSPESAR 12 0 Q8N7B6;D6RF51;D6RGK2;D6RAM4;D6RC23;D6R9D1;D6REJ6;D6RF67;D6RF08;D6RBZ2;D6RDH3;D6REQ4;D6R9F1;D6RB63;D6RC13;Q8N7B6-2;Q8N7B6-3;Q8N7B6-4;D6R9N9 Q8N7B6 PACRGL PACRG-like protein 1 SSLS(0.003)T(0.02)S(0.129)S(0.847)PES(0.001)AR;SSLS(0.003)T(0.021)S(0.132)S(0.843)PESAR 166.11 0.00027929 20770400.0 60503.0 52449.0 64252.0 50549.0 52022.0 54591.0 45398.0 45445.0 51115.0 39451.0 True False 59640.21612510865 52327.55756295695 58969.44857989244 54266.542086520756 48962.168239187165 52256.27018783648 47748.48630588002 47556.54060512905 45357.89043518768 46270.05278484679 1.2889593275899724 1.1309163144091758 1.274462530961379 1.1728221348451275 1.0581826752361525 1.1293756337565741 1.0319522765169054 1.0278038978313762 0.9802861182393584 1.0 15.497791124279182 -6.548288844987865 0.6065437035944995 0.9887126606924216 1.2502635198730692 0.7748966965422012 0.04937238985134351 0.4098046378029377 0.33051752192808653 0.037108944799971295 0.05215694118162943 2.829509490921817e-07 6.548288844987865 0.2615508591806476 SSLVSSS(ph)PASVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSLVSSSPASVR 12 0 S4R3K6;Q86VQ0 S4R3K6 LCA5 Lebercilin 1 SSLVS(0.225)S(0.225)S(0.523)PAS(0.027)VR 81.565 0.045353 0.0 16824.0 19133.0 24172.0 34055.0 38863.0 26062.0 26594.0 29783.0 26079.0 17592.0 True False 19671.970910853444 21032.39779440811 24748.352152820484 32147.008757799656 31248.074130379806 24695.262840471107 24074.823796113396 29001.22780769696 26460.356038379225 20781.290341804633 0.9466193189784934 1.0120833426834106 1.1908958368689706 1.546920726723653 1.503663806068851 1.1883411681512837 1.1584855126961646 1.3955450951646013 1.2732778188056164 1.0 14.342997615693767 -5.347490141496126 3.39052630311718 1.3128042346486353 0.9715934811531265 0.38521690813214204 0.15543238642192098 0.23387091224239748 5.0897751678943495 0.042937318686404644 0.10492666648762508 4.4927252306060966e-06 5.347490141496126 -0.3412107534955088 SSMS(ph)LYTAASVIDTASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSMSLYTAASVIDTASK 17 0 Q96PE2;A0A2R8Y4D7 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 S(0.006)S(0.397)MS(0.518)LY(0.077)T(0.002)AASVIDTASK 99.01100000000001 0.0011445000000000001 2911000.0 23128.0 21034.0 17344.0 18251.0 21858.0 17614.0 14525.0 15096.0 11195.0 11634.0 True False 27043.113601177993 23122.116511136777 17757.54673748628 17228.455640540353 17575.08180896589 16690.290832325147 13149.086848106605 14699.745995534144 11358.705696140778 13743.152105306674 1.9677518951955553 1.6824463801290959 1.2921014481553703 1.2536029222792267 1.2788246593137527 1.2144441613129267 0.9567737260966004 1.0696051300966172 0.8264993073717649 1.0 13.746425315666746 -1.5228787452848542 0.3438518136356922 0.9446115186340147 12.80499226945599 0.9195434597529666 0.09262151343818364 15.924955129786085 0.22513314066874546 0.08345028634730116 121.72049229587847 0.029999999999688 1.5228787452848542 11.860380750821976 SSNIS(ph)QASR ddPTM_PC-9_Lapatinib_30min_R1 1 SSNISQASR 9 0 A0A590UJB2;A0A0C4DG82;A0A2R8YDP4;Q15858-4;Q15858-3;Q15858-2;Q15858 A0A590UJB2 SCN9A Sodium channel protein type 9 subunit alpha 1 S(0.008)S(0.008)NIS(0.983)QASR 90.37 0.008626 19678000.0 44727.0 39156.0 33382.0 42332.0 48522.0 33014.0 42166.0 31942.0 34251.0 33156.0 True False 44089.18477807276 39065.33668773748 30637.460818246404 45445.23649541229 45668.0313579224 31602.068179392852 44349.14916017747 33426.14193000401 30393.291700980397 38886.97042240707 1.1337778258156137 1.0045867873838696 0.7878592877112583 1.1686494474053006 1.1743787407930348 0.8126647006983969 1.1404629540033038 0.8595717683047771 0.7815803435144301 1.0 15.246999222271642 -6.767465721197628 24.99997497486239 0.9239296526863978 1.0427139869599118 0.18504168027502832 0.1404817272935604 312.6049409589966 1296817.3440229446 0.05080565270667189 0.04594995756820161 1.7081825413466523e-07 6.767465721197628 0.11878433427351398 SSPGAVAGLS(ph)NAPGTPR ddPTM_PC-9_AZD4547_30min_R2 1 SSPGAVAGLSNAPGTPR 17 0 U3KPY3;V9GYB2;Q9BWG4-2;Q9BWG4 U3KPY3 SSBP4 Single-stranded DNA-binding protein 4 1 S(0.056)S(0.068)PGAVAGLS(0.869)NAPGT(0.006)PR 61.419 0.032235 5375900.0 8379.6 8829.1 11724.0 13202.0 13323.0 12476.0 11510.0 12654.0 9070.8 9330.2 True False 11044.138493492326 11682.933912539214 11568.532099674478 10158.482868866737 11473.331421719942 11695.87374775677 12534.367702175477 10698.615059992353 9550.263969594775 9003.552537891856 1.2266423111335856 1.2975915743670137 1.284885277337783 1.12827495881368 1.274311597942469 1.2990287665378926 1.392158000902869 1.1882659666800133 1.060721746155427 1.0 13.136278643608135 -8.217991598449302 2.872439414319047 1.0130350835190634 1.269664734964052 0.6902910437976202 0.06395490427303259 0.15713324388976335 2.384567629304483 0.059676204365980465 0.01774409191938944 6.05352585359169e-09 8.217991598449302 0.2566296514449886 SSPGAVAGLSNAPGT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 SSPGAVAGLSNAPGTPR 17 0 U3KPY3;V9GYB2;Q9BWG4-2;Q9BWG4 U3KPY3 SSBP4 Single-stranded DNA-binding protein 4 1 SSPGAVAGLSNAPGT(1)PR;SSPGAVAGLSNAPGT(1)PR;SSPGAVAGLSNAPGT(1)PR 191.41 1.5928e-42 0.0 16852.100000000002 20114.5 21425.0 27307.2 24096.699999999997 21900.0 23881.9 30558.1 26695.5 26822.3 True False 22210.71725454463 26616.11876451394 21140.8905011537 21011.946932034356 20751.28914431876 20530.589537982803 26007.342834629406 25836.04780028071 28106.569630056583 25883.25944107271 0.8581112941015332 1.028314027648245 0.8167785262626697 0.8117967901172316 0.8017262737547531 0.7931995421490057 1.0047939632115959 0.9981759777627897 1.0858976124720916 1.0 14.65973168480017 -7.352105901403691 5.857219321140408 1.024984509021845 0.8542953676041576 0.6071505631874752 0.06727719289619798 0.18184075643242434 9.451309567292121 0.03118701435605774 0.020829684530406005 4.445228586894499e-08 7.352105901403691 -0.17068914141768743 SSPGAVAGLSNAPGT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPGAVAGLSNAPGTPR 17 0 U3KPY3;V9GYB2;Q9BWG4-2;Q9BWG4 U3KPY3 SSBP4 Single-stranded DNA-binding protein 4 1 SSPGAVAGLSNAPGT(1)PR;SSPGAVAGLS(0.002)NAPGT(0.998)PR 203.93 8.7116e-17 5958300.0 10995.8 12421.8 16907.6 12784.4 17958.9 17244.0 15155.9 18078.3 17025.4 13684.400000000001 True False 12857.171763050543 13654.954211183742 17310.741306430078 12068.131515584022 14439.982464042345 16339.694283672921 13720.223432786144 17603.763780542187 17274.364266107652 16165.273394349198 0.7953575203711031 0.8447091415080568 1.0708597921072769 0.746546700521787 0.8932717753533352 1.0107898508777893 0.84874676091666 1.0889864557871216 1.0686094719651418 1.0 13.98061028672495 -7.7642679777058135 24.999986447775314 1.0590985074817942 0.8921931439365998 0.4013135461851579 0.09230214748109608 75.42712625915851 666620.5990118044 0.04764099308831951 0.0244728679665303 1.7208064383930754e-08 7.7642679777058135 -0.16690536354519447 SSPGAVAGLSNAPGT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 SSPGAVAGLSNAPGTPR 17 0 U3KPY3;V9GYB2;Q9BWG4-2;Q9BWG4 U3KPY3 SSBP4 Single-stranded DNA-binding protein 4 1 SSPGAVAGLSNAPGT(1)PR;SSPGAVAGLSNAPGT(1)PR 188.71 2.7968999999999998e-42 6068400.0 15585.2 15119.3 12535.0 10639.400000000001 14647.099999999999 16595.5 17536.6 14051.6 16037.6 18723.7 True False 15362.952190024367 15084.292189777025 11504.420686499272 11421.856967997957 13785.586375306557 15885.749150999995 18444.559340757198 14704.488633887795 14231.276604585062 21960.066597237987 0.699585865188434 0.6868964683228348 0.5238791346810503 0.5201194139108182 0.627757038634866 0.7233925762774333 0.8399136340996821 0.6696012768803371 0.6480525248668869 1.0 14.422594809091072 -6.800347743593437 3.5890295545080853 0.7637171114163664 0.604066551238567 0.3756218381725701 0.10664229165597931 0.28540889231326333 7.635939723979473 0.039296986262795194 0.03576266177841085 1.5836246618078854e-07 6.800347743593437 -0.15965056017779944 SSPGQT(ph)PEEGAQALAEFAALHGPALR ddPTM_PC-9_AZD4547_30min_R2 2 SSPGQTPEEGAQALAEFAALHGPALR 26 0 Q14166 Q14166 TTLL12 Tubulin--tyrosine ligase-like protein 12 1 S(0.251)S(0.251)PGQT(0.498)PEEGAQALAEFAALHGPALR;S(0.264)S(0.264)PGQT(0.472)PEEGAQALAEFAALHGPALR 148.36 8.5553e-12 19354700.0 26399.9 23350.2 34520.0 46454.0 39050.0 38355.0 31060.0 43148.0 31743.2 38209.0 True False 34794.519047967464 30897.695511951762 34062.24224503268 35744.74800714551 33628.581552065145 35956.655786727395 33824.27982880712 36480.468042401604 33421.08074697279 36871.314539914456 0.9436744928174776 0.8379873594825038 0.9238141539043621 0.969445989468333 0.912052688429675 0.975193215522682 0.9173602908079446 0.9893997135065595 0.9064249854936235 1.0 15.170211232010702 -1.5228787501791545 0.09599149050056054 1.0256917458800365 0.6531244254570229 0.25578663904430965 0.03970959009864767 177.00069629304062 1.21592405447033 0.5682265379992935 8.676893597117783 0.029999999661601714 1.5228787501791545 -0.37256732042301366 SSPGQT(ph)PEEGAQALAEFAALHGPALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPGQTPEEGAQALAEFAALHGPALR 26 0 Q14166 Q14166 TTLL12 Tubulin--tyrosine ligase-like protein 12 1 S(0.29)S(0.29)PGQT(0.42)PEEGAQALAEFAALHGPALR;S(0.258)S(0.258)PGQT(0.484)PEEGAQALAEFAALHGPALR 158.75 2.9513e-10 855626000.0 21203.0 23814.0 25219.1 28935.0 33020.0 25923.0 25739.0 23157.0 22954.2 21094.0 True False 24792.249121661047 26178.09653875684 25820.41898796936 27313.865758535718 26549.96803605332 24563.55224516664 23300.81558577734 22549.153286869634 23289.861749920008 24918.175219987883 0.9949464157300802 1.0505623428539952 1.036208260035741 1.0961422944255628 1.0654860479011525 0.9857685014375858 0.9350931751650421 0.9049279527010485 0.9346535829492949 1.0 14.604910801945646 -6.9795318888440105 3.2534906024946024 0.9367274644164822 1.0504650463265652 0.6935097064606105 0.032821394820272486 0.13389406313780725 2.949550475163813 0.013048708976440466 0.010766714779921346 1.0482578205620226e-07 6.9795318888440105 0.11373758191008299 SSPGQT(ph)PEEGAQALAEFAALHGPALR ddPTM_PC-9_Lapatinib_30min_R1 2 SSPGQTPEEGAQALAEFAALHGPALR 26 0 Q14166 Q14166 TTLL12 Tubulin--tyrosine ligase-like protein 12 1 S(0.271)S(0.271)PGQT(0.459)PEEGAQALAEFAALHGPALR;S(0.326)S(0.326)PGQT(0.349)PEEGAQALAEFAALHGPALR 124.39 1.1427e-11 11196700.0 24009.4 19154.2 27641.5 18293.3 22795.8 23730.5 19959.0 21045.5 27855.7 15420.2 True False 23667.02155321529 19109.849626730538 25368.922569275626 19638.650306659885 21454.995862267155 22715.601833497356 20992.379359862956 22023.350760375033 24718.297732474944 18085.561023875056 1.3086141769100805 1.0566357107475572 1.4027169262698393 1.085874542721377 1.1863052428367609 1.2560075854716426 1.1607259145652469 1.2177311354235367 1.366742104369552 1.0 14.142550731416978 -10.607850768621356 4.4024313387796 0.9999836089212669 1.2202957963600265 0.2882846004613622 0.10647237253698251 70388418.73098941 1.423803026019194 14725.206007158218 0.02398111980059324 2.4668868582141442e-11 10.607850768621356 0.22031218743875958 SSPGQTPEEGAQALAEFAALHGPALR ddPTM_PC-9_AZD4547_30min_R2 1 SSPGQTPEEGAQALAEFAALHGPALR 26 0 Q14166 Q14166 TTLL12 Tubulin--tyrosine ligase-like protein 12 0 179.66 6.3903e-18 1142300.0 3546.9 4355.2 3852.0 5401.1 6035.4 5832.0 4249.3 5071.0 4030.1 3976.3 False True 4674.740419896887 5762.933229422115 3800.9199631479096 4155.959841163165 5197.488888587294 5467.324118060073 4627.479468015135 4287.39346998745 4243.122858387785 3837.0909472915273 1.2183032625788106 1.50190165116883 0.9905733315575568 1.0831017294746992 1.3545388837489052 1.4248617489557478 1.2059863921863818 1.1173551862287174 1.1058176406746005 1.0 11.90579724497717 -7.815580413743437 2.5701874714052497 1.0648698489762285 1.2599184182849663 0.25834248053036424 0.14389571371098908 0.45689015833950897 5.985317437896766 0.10256471568679999 0.04312852012794268 1.5290426034623663e-08 7.815580413743437 0.19504856930873782 SSPGQTPEEGAQALAEFAALHGPALR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPGQTPEEGAQALAEFAALHGPALR 26 0 Q14166 Q14166 TTLL12 Tubulin--tyrosine ligase-like protein 12 0 119.69 5.2069e-12 847720.0 3969.8 4469.1 5913.7 2873.4 3793.6 4477.2 2723.2 3896.2 5251.9 2147.2 False True 3913.1899240278412 4458.752073530687 5427.498413542144 3084.719421381406 3570.467906504562 4285.720592862957 2864.1939712800645 4077.2316757773947 4660.375717041221 2518.3406590358436 1.5538763232794808 1.7705118874734513 2.1551883356479986 1.2249015677499338 1.417785911407049 1.7018033590831838 1.1373338078799204 1.6190151483867867 1.8505739882012084 1.0 11.298257736050815 -5.772185296267178 24.9999656314492 1.4470908390019153 1.8209242115858708 0.3009587821678287 0.28087195274957794 272.49434355420385 633947.8726045042 0.07835941677441949 0.11755389059179552 1.6897198412423088e-06 5.772185296267178 0.37383337258395555 SSPGSVAAS(ph)PSGGGGR ddPTM_PC-9_AZD4547_30min_R2 3 SSPGSVAASPSGGGGR 16 0 Q9BXB5-2;Q9BXB5 Q9BXB5-2 OSBPL10 Oxysterol-binding protein-related protein 10 1 SSPGS(0.001)VAAS(0.648)PS(0.351)GGGGR;SSPGSVAAS(0.943)PS(0.056)GGGGR;SSPGSVAAS(0.998)PS(0.002)GGGGR 157.07 8.526799999999998e-15 0.0 9639.8 7416.4 16190.099999999999 30492.1 23072.0 18678.0 17769.4 24338.3 18010.199999999997 20264.0 True False 12705.055879703976 9813.606264393407 15975.408695576587 23462.617443248837 19868.851051709258 17510.061707326156 19350.842176110942 20577.37497349546 18962.18240344797 19554.563527881568 0.6497233170962201 0.501857597097518 0.816965751897162 1.1998538044480016 1.0160723364333635 0.895446307577242 0.9895819023789433 1.052305511404309 0.9697062466472871 1.0 14.255217713974266 -5.4949539308620405 4.78035293604315 1.014212241402913 0.5866281206501502 0.8270194959353828 0.0807227989284134 0.0737724447386847 4.258487720244075 0.022277263861812144 0.04524202575085572 3.199234460438247e-06 5.4949539308620405 -0.42758412075276286 SSPGSVAAS(ph)PSGGGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPGSVAASPSGGGGR 16 0 Q9BXB5-2;Q9BXB5 Q9BXB5-2 OSBPL10 Oxysterol-binding protein-related protein 10 1 SSPGSVAAS(0.951)PS(0.049)GGGGR 150.01 2.6806e-10 0.0 4422.8 4061.9 4825.0 5629.4 7187.5 6433.2 4537.7 5356.1 6202.4 3653.1 True False 5171.492685718175 4465.138587838092 4940.046298914398 5314.002968761047 5779.160970900465 6095.83166699865 4107.856205896955 5215.508050257046 6293.098366212022 4315.37811207631 1.198386920313213 1.0347039058623129 1.1447539869310628 1.2314107433344368 1.3392015301574276 1.4125834419792451 0.9519110722653438 1.2085865745255973 1.4582959367108963 1.0 12.07527125809144 -5.694814808990793 4.118409254992464 1.2386296313735825 1.1115021564363918 0.08292110427771027 0.15566650061775014 0.505661580974502 16.826741023478156 0.043755191957203156 0.07716426439625837 2.019227215073239e-06 5.694814808990793 -0.12712747493719068 SSPGSVAAS(ph)PSGGGGR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPGSVAASPSGGGGR 16 0 Q9BXB5-2;Q9BXB5 Q9BXB5-2 OSBPL10 Oxysterol-binding protein-related protein 10 1 S(0.001)S(0.001)PGS(0.09)VAAS(0.71)PS(0.198)GGGGR 66.738 0.026197 2257000.0 4571.3 4432.5 4211.5 4338.2 5554.5 4784.4 4406.5 5385.7 5785.8 4733.3 True False 4506.11242372625 4422.236818581989 3865.246726860128 4657.245699810963 5227.795230567164 4579.782364981132 4634.647008829908 5635.939283464485 5134.142276824979 5551.444598274198 0.8117008724408571 0.7965920834293742 0.6962596236773639 0.8389250072420396 0.9416999734073455 0.824971281602066 0.8348542306034543 1.0152203059392062 0.9248299583897589 1.0 12.438647523436238 -7.166725726979686 0.4696470587335356 1.003145545568698 0.7626232013824411 0.5851890802121964 0.060867927127695225 0.7770136916077375 0.37607916778140826 0.06374068603689566 0.06609341712573495 6.811994254976773e-08 7.166725726979686 -0.24052234418625684 SSPMKGCS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 SSPMKGCSR 9 1 A7MD48 A7MD48 SRRM4 Serine/arginine repetitive matrix protein 4 1 SSPMKGCS(1)R 83.75299999999999 0.030083999999999996 4148600.0 26584.0 27486.0 28742.0 36378.0 35148.0 29765.0 27202.0 29273.0 23714.0 28087.0 True False 35037.159018449594 36370.31198197471 28360.86230031082 27991.614134497344 30268.30689864238 27903.789844660176 29622.925302743446 24749.53047662051 24967.473626909497 27103.682679017435 1.2927084276106116 1.3418955797520136 1.0463840886931075 1.0327605464539809 1.116759934696065 1.029520238084183 1.0929483514679836 0.9131427182690782 0.9211838082150473 1.0 14.726201268833092 -2.6688456844937254 0.3634019611799446 0.9630961857578367 3.1270733550485246 0.7164913314419317 0.07157727376591591 15.120080501250538 0.45797501135286217 0.06146204921378824 19.62725474330381 0.0021436521581241932 2.6688456844937254 2.1639771692906877 SSPNPFVGS(ph)PPK ddPTM_PC-9_AZD4547_30min_R2 2 SSPNPFVGSPPK 12 0 P98082-3;P98082 P98082-3 DAB2 Disabled homolog 2 1 SSPNPFVGS(1)PPK;SSPNPFVGS(1)PPK 90.75399999999999 0.006776300000000001 14482600.0 101902.0 111113.0 101511.0 116329.0 107011.0 111571.0 115632.0 122792.0 127347.0 128618.0 True False 134304.71630672753 147028.1043168578 100164.8978138908 89511.14631513397 92154.36979431605 104594.44773252429 125923.02399113408 103817.31787945176 134078.30243594677 124115.12296827238 1.082097919212149 1.1846107130268297 0.8070321764052557 0.7211945182378441 0.7424910646696417 0.8427212190674124 1.0145663234231646 0.8364598559515639 1.0802736945297253 1.0 16.921319387665477 -5.260227087744607 24.99967317887742 0.8675589093590257 1.1333543330974807 0.4332060117246179 0.11487641357032045 94.32111538822038 1945017.606704318 0.031080279380646524 0.07329898622271941 5.492536001716743e-06 5.260227087744607 0.265795423738455 SSPNPFVGS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPNPFVGSPPK 12 0 P98082-3;P98082 P98082-3 DAB2 Disabled homolog 2 1 SSPNPFVGS(1)PPK 74.789 0.020452 7403700.0 34666.0 36464.0 32766.0 43860.0 43944.0 37055.0 40037.0 45542.0 28277.0 32713.0 True False 40534.26911529037 40083.904937819294 33547.26570574697 41402.666396038585 35333.48865464347 35111.77056840063 36244.405517221596 44346.57075573764 28690.49763017177 38643.607944034484 1.048925586192522 1.0372712867771228 0.8681193990564162 1.0713975376212257 0.9143423850540849 0.9086048750740658 0.9379146370005739 1.1475784253882932 0.7424383787280607 1.0 15.237942176620907 -5.043279005223553 22.469269328966053 0.9552137785139775 1.046012209576324 0.11304182915117211 0.10465086684670898 271.4384114539991 140924.17624373472 0.024934394555395215 0.06599171331662827 9.051509150100977e-06 5.043279005223553 0.09079843106234653 SSPNPFVGS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 2 SSPNPFVGSPPK 12 0 P98082-3;P98082 P98082-3 DAB2 Disabled homolog 2 1 S(0.023)S(0.057)PNPFVGS(0.92)PPK;SSPNPFVGS(1)PPK 112.17 0.00098521 12951000.0 56747.0 72858.0 56647.0 71408.0 76446.0 73269.0 76808.0 71154.0 69085.0 68908.0 True False 55937.777373874706 72689.30177738231 51989.70232374348 76659.5825301051 71949.59657861869 70135.45566838105 80784.74241556964 74460.07460044768 61303.9198026986 80818.65598586145 0.6921394162216773 0.899412405349808 0.6432883805050983 0.9485382006787647 0.8902597513030366 0.8678126951362649 0.9995803744831175 0.9213228516627875 0.7585367395050866 1.0 16.302400739253756 -5.781692037388999 24.999027105994855 0.9098803311815663 0.7603932453285451 0.41884222031385376 0.08975024462296949 237.05694185240182 292612.2727005768 0.024298111970172977 0.03608865061291098 1.6531336364855944e-06 5.781692037388999 -0.14948708585302117 SSPNPFVGS(ph)PPKGLSIQNGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPNPFVGSPPKGLSIQNGVK 21 1 P98082-3;P98082 P98082-3 DAB2 Disabled homolog 2 1 S(0.001)S(0.001)PNPFVGS(0.948)PPKGLS(0.05)IQNGVK 55.468999999999994 0.0081128 5010200.0 13848.0 4207.1 11296.0 18997.0 18080.0 19904.0 18116.0 22360.0 21002.0 15924.0 True False 16192.192889532715 4624.753084244725 11565.339480318562 17932.659679104974 14537.353788365963 18860.19920101056 16399.92133151801 21773.073692378326 21309.114518119582 18810.89514568535 0.8607880041927038 0.24585502435834392 0.6148213251282356 0.9533124043391514 0.7728156302918094 1.0026210371672035 0.8718309896740696 1.1574714293898134 1.132807043635414 1.0 14.199280882930147 -6.162536683216326 0.8138453416259579 1.0644604562441606 0.5151027098983951 0.5287940197528401 0.1758924732061726 0.5224869158644676 0.7283720371847128 0.09164636569505188 0.17680508517778884 6.878018138309721e-07 6.162536683216326 -0.5493577463457655 SSPNPFVGS(ph)PPKGLSIQNGVK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPNPFVGSPPKGLSIQNGVK 21 1 P98082-3;P98082 P98082-3 DAB2 Disabled homolog 2 1 SSPNPFVGS(0.966)PPKGLS(0.034)IQNGVK 55.994 0.0077547 5046500.0 46242.0 22834.0 24756.0 22557.0 22641.0 24502.0 16104.0 16964.0 27501.0 23255.0 True False 45582.58060025577 22781.129275916788 22720.657240923498 24215.91702794613 21309.300893918666 23454.106576951683 16937.786322522825 17752.209370126726 24403.547781631547 27274.595764660276 1.6712467892674387 0.8352508492695727 0.8330336932202191 0.887856129450788 0.7812875056989533 0.8599249931814276 0.6210096189388491 0.6508697515923695 0.8947354524407379 1.0 14.735270194149967 -4.760889998900011 5.786128792489026 0.8016203761590321 1.707788995266484 0.8496906144186841 0.10752229984425479 0.050562343470261506 5.990607529336574 0.027165292847375837 0.18259083502637777 1.734243203202025e-05 4.760889998900011 0.9061686191074518 SSPNVANQPPS(ph)PGGK ddPTM_PC-9_AZD4547_30min_R2 4 SSPNVANQPPSPGGK 15 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 SSPNVANQPPS(1)PGGK;SSPNVANQPPS(1)PGGK;SSPNVANQPPS(1)PGGK;SSPNVANQPPS(1)PGGK 180.76 1.9402e-05 162870000.0 186221.0 157685.0 184549.0 222979.0 213401.0 166002.0 163365.0 203798.0 165535.0 173918.0 True False 245435.40436257469 208653.59255176014 182101.7596778256 171574.63654120866 183773.95471939162 155621.86869790946 177904.16852006057 172305.70191214787 174284.8421535996 167829.18375651896 1.4624119528498944 1.2432497607476176 1.0850422769261205 1.0223170529752648 1.0950059495373867 0.9272634545114664 1.0600311849109512 1.0266730615941224 1.038465648539686 1.0 17.356634081751686 -4.745810586358235 1.2013254097903627 1.021843305734917 1.6996023592432223 0.9207585799495013 0.04065569966699217 0.39299809558918575 0.4558342652079677 0.011954861307360712 0.3417961230923552 1.7955165545224393e-05 4.745810586358235 0.6777590535083053 SSPNVANQPPS(ph)PGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSPNVANQPPSPGGK 15 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 SSPNVANQPPS(1)PGGK;SSPNVANQPPS(1)PGGK;SSPNVANQPPS(1)PGGK;SSPNVANQPPS(1)PGGK 183.6 5.3067e-07 125063000.0 142736.0 142153.0 130494.0 156073.0 177956.0 157995.0 156149.0 188235.0 144322.0 129279.0 True False 166898.38563549568 156265.01038355194 133605.47186125116 147328.73580549296 143086.79926783487 149709.46406569838 141357.43629913905 183294.03070146873 146432.43621960093 152716.25932799873 1.0928658570469374 1.0232375457018714 0.8748608199883807 0.9647220044138547 0.9369454169285142 0.9803112302807099 0.9256213904214116 1.2002260368871143 0.9588529529465384 1.0 17.22049414497439 SSPNVANQPPS(ph)PGGK ddPTM_PC-9_Lapatinib_30min_R1 4 SSPNVANQPPSPGGK 15 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 SSPNVANQPPS(1)PGGK;SSPNVANQPPS(1)PGGK;SSPNVANQPPS(1)PGGK;SSPNVANQPPS(1)PGGK 199.09 6.2188e-10 153104000.0 161413.0 144119.0 130203.0 131459.0 138587.0 124298.0 123766.0 124280.0 152021.0 132265.0 True False 159111.22102048132 143785.3013101447 119498.21193811452 141126.9333943685 130435.58513252513 118982.06429279016 130173.99788831109 130054.50250644588 134898.79412790114 155126.82901796544 1.0256847382734449 0.9268886769644002 0.7703258855647418 0.9097519383834269 0.8408318919315962 0.7669986232943026 0.839145612092899 0.8383753044509412 0.8696032464653702 1.0 17.24308869494292 -4.949832333969705 3.7691470173860484 0.846174836142602 1.0203278015327788 0.40414106634244995 0.06390354572441873 0.20112205846292128 5.7044382230961395 0.015293178594492604 0.07547220355556772 1.1224517103225038e-05 4.949832333969705 0.17415296539017677 SSPPAPPLPPGS(ph)GSPGTPQALPR ddPTM_PC-9_AZD4547_30min_R2 3 SSPPAPPLPPGSGSPGTPQALPR 23 0 Q9Y3L3;A0A2R8Y5V0 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 SSPPAPPLPPGS(0.487)GS(0.487)PGT(0.025)PQALPR;S(0.092)S(0.092)PPAPPLPPGS(0.758)GS(0.056)PGT(0.001)PQALPR;SSPPAPPLPPGS(0.484)GS(0.484)PGT(0.033)PQALPR 242.8 1.4599999999999996e-126 72447000.0 32716.300000000003 44845.1 69027.6 99180.0 84394.0 65595.0 69666.3 89769.0 71056.0 80371.0 True False 43119.402858685746 59340.40158127246 68112.24892216732 76315.58331572505 72677.34984647861 61493.334280547126 75866.465738494 75897.26373640393 74811.87509630095 77557.23575302854 0.5559687944010043 0.7651175419690648 0.8782191404946713 0.9839905016566426 0.9370801981379362 0.7928768177912513 0.978199712791227 0.9785968130438456 0.9646021337651867 1.0 16.24297376426717 -4.774251122405805 1.342279505499278 0.9424994586831897 0.3821711462323059 0.8240497913264027 0.05638041243180221 0.5631477792242706 0.8873279226594118 0.01755157317587689 0.4365984381354338 1.681701368504051e-05 4.774251122405805 -0.5603283124508838 SSPPAPPLPPGS(ph)GSPGTPQALPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPPAPPLPPGSGSPGTPQALPR 23 0 Q9Y3L3;A0A2R8Y5V0 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 SSPPAPPLPPGS(0.333)GS(0.333)PGT(0.333)PQALPR;S(0.087)S(0.087)PPAPPLPPGS(0.393)GS(0.393)PGT(0.04)PQALPR 191.19 8.426700000000001e-21 68251000.0 20710.5 21167.2 29851.0 29293.0 42314.0 34764.0 31591.0 31860.2 33482.0 20377.9 True False 24216.378598979434 23268.539726848645 30562.761050547917 27651.80817918737 34022.87545359057 32940.914641475625 28598.47178096629 31023.903508672294 33971.610908279195 24072.251958632372 1.0059872520690936 0.9666125033434807 1.269626169710642 1.1487005132177242 1.413364878037091 1.3684184885603496 1.1880264393257485 1.288782767893348 1.4112352665076227 1.0 14.555083491764007 -5.264504919008288 23.743459803221707 1.2739913255713886 0.986299840995998 0.44931005396991497 0.12097495701438303 99.79181635489257 772932.90241357 0.030385897098683407 0.06802580467820839 5.438699715775556e-06 5.264504919008288 -0.2876914845753906 SSPPAPPLPPGS(ph)GSPGTPQALPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPPAPPLPPGSGSPGTPQALPR 23 0 Q9Y3L3;A0A2R8Y5V0 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 SSPPAPPLPPGS(0.343)GS(0.343)PGT(0.313)PQALPR 150.13 2.7512e-06 16147000.0 25449.0 24937.0 19917.0 19444.0 17713.0 16467.0 17594.0 19872.0 20739.0 12608.0 True False 25086.09259322496 24879.259908624706 18279.50114184334 20873.976623282542 16671.156165097887 15762.744796451869 18504.93123189685 20795.325666302666 18403.155428648275 14787.276000896003 1.69646475738364 1.6824775507752205 1.2361641955378213 1.4116174352881308 1.1273987287508351 1.0659667673408382 1.2514090648457217 1.4062986086851033 1.2445264041553816 1.0 13.852068694194369 -5.259400700664977 6.002346441055427 1.231022951609516 1.6937918366457119 0.6953102234534584 0.1246331517869216 0.08216489368678784 13.692272546927152 0.03342274531302537 0.08071259297986573 5.502997295017729e-06 5.259400700664977 0.46276888503619595 SSPPAPPLPPGSGS(ph)PGTPQALPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPPAPPLPPGSGSPGTPQALPR 23 0 Q9Y3L3;A0A2R8Y5V0 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 SSPPAPPLPPGS(0.158)GS(0.81)PGT(0.032)PQALPR 226.72 4.864499999999999e-109 0.0 4578.7 6001.7 5672.6 10585.0 11283.0 8322.5 6097.7 8304.0 7179.4 6334.6 True False 5353.783476552822 6597.509112146503 5807.856297455302 9991.956767033022 9072.177145693202 7886.0534490760765 5520.081712475017 8086.028798815284 7284.385142909608 7483.012835333988 0.7154582778841202 0.8816648130006899 0.7761387592483103 1.3352852636911257 1.2123695823232254 1.0538607406683809 0.7376817110896537 1.0805846490913285 0.9734561871273986 1.0 12.869403534381437 -5.659583410250248 23.205128191516845 1.0529903801125637 0.8001175816446189 0.3915593820480152 0.15126396530966096 8.240308330330231 1861.3035645836608 0.04438266081464765 0.07687299237034037 2.189861204688947e-06 5.659583410250248 -0.25287279846794486 SSPPAPPLPPGSGS(ph)PGTPQALPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPPAPPLPPGSGSPGTPQALPR 23 0 Q9Y3L3;A0A2R8Y5V0 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 SSPPAPPLPPGS(0.142)GS(0.729)PGT(0.129)PQALPR 218.22 9.527399999999998e-38 52460000.0 42058.0 34514.0 31149.0 36376.0 28760.0 24905.0 20197.0 23681.0 23861.0 20392.0 True False 41458.24520750742 34434.08495353384 28588.049458617148 39051.21238677877 27068.39334433553 23839.871206390573 21242.70183532003 24781.305711740803 21173.52291253081 23916.730029367965 1.7334412002225963 1.4397488666406881 1.1953159743624295 1.6327989795773412 1.1317765142265501 0.9967863991907332 0.8881942393143031 1.036149410112135 0.8853017484635776 1.0 14.545732532760194 -6.465553065168671 3.584507811735212 0.9631065377892031 1.4734075083125664 0.767588490947311 0.13956216468467184 0.12121672080874153 3.1042360919888075 0.046496278142685095 0.05132837705178537 3.423315565822839e-07 6.465553065168671 0.5103009705233633 SSPPAPPLPPGSGSPGT(ph)PQALPR ddPTM_PC-9_AZD4547_30min_R2 1 SSPPAPPLPPGSGSPGTPQALPR 23 0 Q9Y3L3;A0A2R8Y5V0 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 SSPPAPPLPPGS(0.443)GS(0.112)PGT(0.445)PQALPR 109.12 3.3049e-06 62391000.0 28170.0 26019.0 44155.0 68442.0 55363.0 47961.0 36288.0 48139.0 36152.0 49736.0 True False 37127.47402760026 34429.132920723285 43569.47584963551 52663.75431835906 47676.80308494191 44961.99108818233 39517.56170082912 40700.223674171946 38062.92091422923 47994.75777846018 0.7735735264875718 0.7173519466364494 0.907796556672889 1.0972813856348766 0.9933752203733182 0.9368104595031639 0.8233724583680349 0.848013940648285 0.7930641319188341 1.0 15.55058921579921 -5.296419451891019 7.080567204613695 0.925306963673479 0.7454280833366206 0.4056520974288662 0.08695306271201006 0.21570524041460126 36.07686451291337 0.025550211185860018 0.05496117330811898 5.053363604155028e-06 5.296419451891019 -0.1798788803368584 SSPPAPPLPPGSGSPGT(ph)PQALPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPPAPPLPPGSGSPGTPQALPR 23 0 Q9Y3L3;A0A2R8Y5V0 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 SSPPAPPLPPGS(0.011)GS(0.039)PGT(0.95)PQALPR;SSPPAPPLPPGS(0.023)GS(0.122)PGT(0.855)PQALPR 248.33 9.875999999999999e-70 55430000.0 32676.7 37483.7 57614.0 62263.0 78054.0 65758.0 60572.0 65217.0 63076.6 44147.7 True False 38208.21991575636 41204.834014856766 58987.736262311766 58774.60596936958 62759.879015327344 62309.53471965697 54834.18165669624 63505.12285312331 63998.975945796665 52151.3285369991 0.7326413533003151 0.7901013295495192 1.1310878920459817 1.1270011257272488 1.2034186045864956 1.1947832676103556 1.051443619845538 1.217708630530269 1.2271782472500614 1.0 15.670416384918205 -5.243655244992868 3.6653389468520743 1.1546611113571597 0.742804350034151 0.8283260510523537 0.06985122998447846 0.0795132773600573 2.3467732608820135 0.017936440773240383 0.05007384048159982 5.706170641921425e-06 5.243655244992868 -0.41185676132300864 SSPPAPPLPPGSGSPGT(ph)PQALPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPPAPPLPPGSGSPGTPQALPR 23 0 Q9Y3L3;A0A2R8Y5V0 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 SSPPAPPLPPGS(0.029)GS(0.014)PGT(0.957)PQALPR 184.91 8.9288e-20 57224000.0 18351.0 18632.0 17198.0 13182.0 12483.0 11374.0 9732.8 8579.1 10689.0 11597.0 True False 18089.311374838748 18588.858748746672 15784.046826199812 14151.44825386291 11748.774482522263 10887.560534088998 10236.716761043857 8977.716305544336 9485.092259839983 13601.52599796883 1.3299471969204113 1.36667450045845 1.1604614679674108 1.0404309234108144 0.8637835551890835 0.8004661047381654 0.752615314088474 0.6600521373031977 0.6973550071702564 1.0 13.731480900598449 -5.892745039614919 1.0372792558107735 0.7498380162502265 1.3815490072052006 0.8644564808367847 0.08917222630293503 0.18109017957017004 0.38685927071097803 0.0343592718800394 0.08332175771965238 1.2801326084697293e-06 5.892745039614919 0.6317109909549741 SSPPLRT(ph)PDVLESSGPAVR ddPTM_PC-9_AZD4547_30min_R2 2 SSPPLRTPDVLESSGPAVR 19 1 E9PJN1;O75676-2;O75676;A0A0A6YYC0 E9PJN1 RPS6KA4 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-4 1 SSPPLRT(0.997)PDVLES(0.001)S(0.002)GPAVR;S(0.017)S(0.017)PPLRT(0.966)PDVLESSGPAVR 103.13 0.00022035 33322000.0 45813.0 49967.0 44720.0 96894.0 71497.0 67004.0 53022.0 93404.0 66271.0 66544.0 True False 60380.58103040288 66117.8555920589 44126.983580471075 74556.58529737713 61570.87567805381 62814.22928780819 57740.85528277565 78970.55801039406 69773.94976507197 64214.31481441721 0.9402978324211039 1.029643558187034 0.6871829701523782 1.1610586442111799 0.9588341144182091 0.9781966757621671 0.899189774891312 1.2297967865673438 1.0865793704522488 1.0 15.97060732190812 -7.748892804598568 24.998483604383598 1.1186410832328717 0.9530048646397036 0.24792776925249127 0.12288474029787402 280.835311775284 559554.1664238392 0.056346507410873874 0.0322444217540161 1.7828187601191192e-08 7.748892804598568 -0.16563621859316813 SSPPLRT(ph)PDVLESSGPAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPPLRTPDVLESSGPAVR 19 1 E9PJN1;O75676-2;O75676;A0A0A6YYC0 E9PJN1 RPS6KA4 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-4 1 S(0.003)S(0.003)PPLRT(0.993)PDVLESSGPAVR 72.48899999999999 0.0040121 8394800.0 13648.0 11681.0 12663.0 12254.0 17926.0 17103.0 18610.0 19674.0 19824.0 13454.0 True False 15958.336839712785 12840.612482960383 12964.933944694936 11567.448108004031 14413.528982867714 16206.08857188924 16847.126075267737 19157.578346326092 20113.88849667663 15893.103698194609 1.0041044935436736 0.8079361166201303 0.815758469264106 0.7278281402843956 0.9069046082235676 1.019693124743796 1.060027443046351 1.205401959876617 1.2655733504690772 1.0 13.956113269670153 -7.020544898080274 1.5513287583244728 1.1650089690900658 0.8348234084714781 0.6705830474471566 0.09375173342025354 0.22072827808708514 1.072202718311008 0.04740996140842849 0.034771809939841455 9.537951328294784e-08 7.020544898080274 -0.3301855606185877 SSPPLRT(ph)PDVLESSGPAVR ddPTM_PC-9_Lapatinib_30min_R1 1 SSPPLRTPDVLESSGPAVR 19 1 E9PJN1;O75676-2;O75676;A0A0A6YYC0 E9PJN1 RPS6KA4 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-4 1 S(0.001)S(0.001)PPLRT(0.997)PDVLES(0.001)S(0.001)GPAVR 59.57899999999999 0.015602000000000001 14050000.0 19881.0 11445.0 8431.9 10700.0 14380.0 20979.0 19492.0 11863.0 16138.0 18113.0 True False 19597.493294271124 11418.499805678699 7738.661730075252 11486.913694153634 13534.196672167765 20081.777074437585 20501.200384911524 12414.19828801068 14320.368499326201 21243.8079159446 0.9225037889540589 0.537497789984653 0.36427846460930285 0.5407182054932863 0.637089015571904 0.9453002566157244 0.9650435772168836 0.5843678467217344 0.6740961204313097 1.0 14.374754769470014 -6.591311675604051 6.57560589385191 0.8152407312046261 0.5732105395970897 0.2995731401029582 0.17743664530178707 0.2891885667763338 21.912334477617097 0.06202997451432756 0.062081005487050395 2.562644270172487e-07 6.591311675604051 -0.24203019160753647 SSPPSAGNSPS(ph)SLK ddPTM_PC-9_AZD4547_30min_R2 2 SSPPSAGNSPSSLK 14 0 P57682;P57682-2 P57682 KLF3 Krueppel-like factor 3 1 SSPPS(0.001)AGNS(0.407)PS(0.571)S(0.02)LK;S(0.005)S(0.009)PPS(0.003)AGNS(0.055)PS(0.718)S(0.209)LK 130.29 1.9913e-05 16626000.0 18627.2 25580.0 28234.0 34814.0 29211.0 31376.0 28298.0 32726.0 30892.0 30178.0 True False 24550.262130170944 33848.234755836165 27859.598712232135 26788.170170938203 25155.55686856272 29414.053759988514 30816.46717951013 27668.948668666806 32524.88805273204 29121.477405468315 0.8430294173729316 1.1623117290567229 0.9566684520957982 0.9198767561809219 0.8638145832477273 1.0100467551988026 1.0582041134260427 0.9501217360445883 1.1168694362541045 1.0 14.829795928474617 -6.981450993332396 24.965510752530363 1.0281399197813934 0.9574910482211506 0.15770483070874608 0.08994400639657828 527.1990864352275 709566.8683214311 0.03180058485125092 0.028040926451189906 1.0436358920689861e-07 6.981450993332396 -0.0706488715602428 SSPPSAGNSPS(ph)SLK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPPSAGNSPSSLK 14 0 P57682;P57682-2 P57682 KLF3 Krueppel-like factor 3 1 S(0.001)S(0.004)PPS(0.034)AGNS(0.112)PS(0.641)S(0.209)LK 94.339 0.01569 0.0 6826.5 8523.4 9529.4 8298.5 15558.0 16404.0 15690.0 17695.0 14657.0 12882.0 True False 6729.152858173217 8503.664590976132 8745.929516547767 8908.799372984482 14642.909028204878 15702.439159591699 16502.35142824039 18517.17429877343 13006.17431494758 15108.636535813957 0.44538452177482957 0.5628346787493891 0.5788695423188027 0.5896494598878463 0.9691747493888608 1.03930219794289 1.0922462387074259 1.2256019432911616 0.8608436826259842 1.0 13.883085851317922 -6.286976580926863 2.445701643935634 1.061256313851892 0.5313131206574786 0.8733936333568513 0.09127510337941251 0.09467371335645852 1.116122162796677 0.029899781115452304 0.037317815257375105 5.164442174702672e-07 6.286976580926863 -0.5299431931944134 SSPQLDPLRKSPTMEQAVQT(ph)AS(ph)AHLPAPAAVGR ddPTM_PC-9_AZD4547_30min_R2 1 SSPQLDPLRKSPTMEQAVQTASAHLPAPAAVGR 33 2 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 2 S(0.378)S(0.393)PQLDPLRKS(0.195)PT(0.198)MEQAVQT(0.417)AS(0.418)AHLPAPAAVGR 41.247 0.02053 6431500.0 8563.1 7734.7 19887.0 37567.0 29656.0 21277.0 12715.0 21355.0 14716.0 22692.0 True False 11285.987676455225 10234.790514697657 19623.285386065025 28906.50855436422 25538.776299821846 19946.5458264685 13846.610367781155 18055.07543908144 15493.857716690567 21897.559986907247 0.5153993268292549 0.4673941078739884 0.896140273062294 1.320078975541005 1.166284111795639 0.9109026685345182 0.6323357659967673 0.8245245337780436 0.7075609212147147 1.0 14.418482500932683 -5.284261019326512 6.2754375114817735 0.9378717351912631 0.48972179481706535 0.46065890900899986 0.19089498635969454 0.15539410021376082 24.498805579786044 0.05728900002554083 0.12791101926873846 5.196835628490953e-06 5.284261019326512 -0.44814994037419775 SSPS(ph)PALEQPFR ddPTM_PC-9_AZD4547_30min_R2 3 SSPSPALEQPFR 12 0 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 S(0.251)S(0.032)PS(0.718)PALEQPFR;S(0.005)S(0.017)PS(0.978)PALEQPFR;S(0.006)S(0.021)PS(0.973)PALEQPFR 111.88 0.0010206 7724500.0 39352.7 48262.5 51763.0 75477.0 65479.9 64198.0 54514.0 71160.0 57171.9 59511.0 True False 51866.04001299055 63862.409300373074 51076.58879865664 58076.94375802567 56389.14615034753 60183.68891138903 59365.640392388654 60163.85709412486 60193.88991525289 57427.538003738635 0.9031562524866376 1.1120520140740757 0.8894093421753769 1.0113082638897868 0.9819182244357488 1.0479935411382422 1.0337486588494156 1.047648204772562 1.048171173755249 1.0 15.809455092310595 -6.756399107734552 24.89852131850574 1.0383801026195791 0.983683430367989 0.1829295084404532 0.05863926626841753 208.1019312626632 1028006.1341099688 0.018385348986802365 0.017846583193442844 1.7522694619496179e-07 6.756399107734552 -0.05469667225159014 SSPS(ph)PEVVKPK ddPTM_PC-9_AZD4547_30min_R2 2 SSPSPEVVKPK 11 1 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 SS(0.001)PS(0.999)PEVVKPK;S(0.189)S(0.189)PS(0.623)PEVVKPK 81.904 0.0068597 46589000.0 93292.0 74911.0 108113.0 126961.0 121531.0 119992.0 100094.0 114618.0 92913.0 111847.0 True False 122956.91540585305 99124.51578555294 106679.35098022083 97692.10297789639 104658.51842776024 112488.8812713072 109002.17209222849 96906.42175961751 97824.19149435096 107931.27057357715 1.1392149351381244 0.9184040478609894 0.9884007703541035 0.9051325205265635 0.9696774426130205 1.0422269716043333 1.0099220690441266 0.8978530619034643 0.9063563411649439 1.0 16.719753387135242 -7.756533951916205 24.999388270288666 0.9265785234201714 0.9901068493493169 0.1429410478665729 0.06689497710993784 225.51764076769766 1149317.1463463085 0.03223263602592766 0.01784860823383158 1.7517254839037514e-08 7.756533951916205 0.06352832592914548 SSPS(ph)PEVVKPK ddPTM_PC-9_Lapatinib_30min_R1 2 SSPSPEVVKPK 11 1 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 S(0.041)S(0.129)PS(0.83)PEVVKPK;S(0.004)S(0.006)PS(0.99)PEVVKPK 90.412 0.0041292 44004000.0 134708.0 111932.0 116170.0 109819.0 126523.0 108616.0 105125.0 104972.0 112549.0 90991.0 True False 132787.0392175784 111672.82833108153 106618.95102916814 117895.45560544447 119081.16589378871 103970.74687626255 110567.85811942449 109849.38233912628 99872.54642648813 106718.67311211344 1.2442718349588062 1.0464225713691502 0.9990655610678317 1.1047312730508676 1.1158418899070066 0.9742507458562191 1.036068523858681 1.0293360958838373 0.9358488398892189 1.0 16.703453108417577 -4.763364376536284 4.838350647842428 1.029723611677638 1.2589355237736113 0.6146463860422825 0.051769563704912695 0.12770936478174902 7.4319083044117855 0.013376583681765373 0.10033867204525639 1.7243905074939332e-05 4.763364376536284 0.22921191209597325 SSPS(ph)TGSLDSGNESKEK ddPTM_PC-9_AZD4547_30min_R2 1 SSPSTGSLDSGNESKEK 17 1 A0A0U1RQT1;A0A087X1H5;Q15057 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 S(0.021)S(0.021)PS(0.523)T(0.358)GS(0.075)LDS(0.002)GNESKEK 55.763000000000005 0.024131 4139800.0 8732.2 9866.6 13185.0 22659.0 24257.0 17425.0 11838.0 14193.0 11019.0 18767.0 True False 11508.857958956729 13055.78549812093 13010.15828507404 17435.317628060246 20889.334256298185 16335.411995404122 12891.559066755273 11999.797972694121 11601.44184426565 18109.973042230216 0.635498348458029 0.7209168930111852 0.7183974407215273 0.9627467466353066 1.1534713059807897 0.902011944319959 0.7118486061074609 0.6626071692493455 0.6406106633738505 1.0 14.14449677830193 -11.439514823165556 7.412154800627292 1.048518124934942 0.7987155135175865 0.1334248788759601 0.15926079746839458 0.10696019804988208 0.0012029718706067598 0.1291688023470025 0.04250751995050757 3.634838980473264e-12 11.439514823165556 -0.2498026114173555 SSPSGASS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 SSPSGASSPR 10 0 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 SSPS(0.001)GAS(0.023)S(0.976)PR;SSPSGAS(0.005)S(0.995)PR;SSPSGAS(0.029)S(0.971)PR;SSPS(0.001)GAS(0.11)S(0.888)PR 112.85 0.0013925 25546300.0 185222.0 139333.0 135956.0 139663.0 115377.0 129448.0 108667.0 121669.0 197576.0 225941.0 True False 244118.74314306662 184369.66744468032 134153.1346079277 107465.85312184007 99358.89510198774 121353.59609647474 118338.15248412677 102867.85172547871 208019.46400060164 218030.87436108835 1.119652177052564 0.8456126591472519 0.6152942100564718 0.4928928228020689 0.4557102079838294 0.5565890447950822 0.5427586933772642 0.471804059984256 0.9540826023386648 1.0 17.73417291739208 -4.942701175078984 2.1770078680154246 0.5985284165965529 1.1690481170835234 0.38949776689728466 0.1846829157307875 0.4127297357503841 2.9420860864947747 0.047650103455127664 0.40753262588841394 1.1410346289960751e-05 4.942701175078984 0.5705197004869705 SSPSGASS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSPSGASSPR 10 0 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 SSPS(0.002)GAS(0.037)S(0.961)PR;SSPSGAS(0.024)S(0.976)PR;SS(0.005)PS(0.006)GAS(0.453)S(0.537)PR 125.23 0.00038651 26142200.0 57301.4 117832.0 107384.0 60497.9 233375.0 235575.0 93485.9 123640.0 214311.0 275401.0 True False 67001.39526576175 129529.58223544093 109944.44181608791 57108.39879983812 187646.84404645508 223221.03229391397 84630.23877269593 120394.58100740884 217444.89293842172 325329.02122688416 0.20594964142173788 0.3981494849336147 0.3379484603047841 0.17554043775274134 0.5767909771430761 0.6861393165973958 0.26013737862529906 0.370070215541717 0.6683845545607684 1.0 18.311539999283063 -14.522878744955417 0.13922399028662702 3.0919016631289207 0.1880687452857416 0.6319122123827501 0.15001515222648423 98.09142235508767 0.8356424945515979 56.58030713694732 0.992707016417258 3.0000000022444728e-15 14.522878744955417 -2.903832917843179 SSPSGASS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 SSPSGASSPR 10 0 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 SSPS(0.004)GAS(0.004)S(0.992)PR;S(0.019)S(0.069)PS(0.034)GAS(0.174)S(0.704)PR;SSPSGAS(0.007)S(0.993)PR 110.84 0.0016819000000000003 24826000.0 43397.700000000004 61822.0 44359.9 46696.6 64577.0 33136.3 83423.0 81406.0 61734.0 43191.4 True False 42778.84083983652 61678.854957332325 40712.80025616587 50130.82373929105 60778.707823266835 31719.13769348807 87742.23474812605 85188.41994721403 54780.86683216029 50656.97594107707 0.8444807461384154 1.2175787008895997 0.803695828655899 0.9896134304898495 1.1998092403692457 0.6261553735537427 1.7320859194237261 1.6816720375551646 1.0814081538519005 1.0 15.628473334905602 -7.264324256266854 24.999937878722566 1.4305975189260782 0.9661226014090177 0.3644303403492598 0.27137236914714497 258.09039397123075 2236558.4481949587 0.10657413222714048 0.07541389535399753 5.440962638377997e-08 7.264324256266854 -0.4644749175170605 SSPSGNTQS(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 3 SSPSGNTQSSPK 12 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 SSPS(0.002)GNT(0.044)QS(0.477)S(0.477)PK;SSPS(0.013)GNT(0.103)QS(0.442)S(0.442)PK;SSPS(0.001)GNT(0.132)QS(0.434)S(0.434)PK 122.1 0.0010397 4227800.0 21569.8 29598.2 16855.8 26926.2 33765.0 15483.3 50160.0 44650.0 23278.399999999998 23701.5 True False 21262.210696583137 29529.66718640799 15469.981189269609 28906.442571170057 31779.00908454411 14821.115352335159 52757.03936523505 46724.60200283887 20656.5414595808 27798.27269473643 0.7648752471087569 1.0622842473230143 0.5565087212126971 1.0398647026958425 1.1432008540070702 0.5331667731693818 1.8978531488118153 1.6808455156886821 0.743087230146213 1.0 14.762707620334263 -7.24919759237254 24.991836158840403 1.3871836309876877 0.8682527495919382 0.29724951723517723 0.3570212154183452 893.6986085614768 1824505.121924933 0.1355942112986634 0.10422946388789235 5.6338127409685255e-08 7.24919759237254 -0.5189308813957495 SSPSGNTQSS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 SSPSGNTQSSPK 12 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 SSPSGNT(0.007)QS(0.198)S(0.795)PK 93.766 0.0051393 1177000.0 11795.0 8134.6 8861.2 7619.9 3825.2 6370.9 6434.5 5828.5 10207.0 11844.0 True False 15545.564648759128 10763.950369226934 8743.694698194775 5863.249781281442 3294.1370077582446 5972.5266158691575 7007.158034721814 4927.83925060577 10746.521181996506 11429.345165033024 1.3601448223227415 0.9417818968455164 0.7650214926525505 0.5129996247921086 0.28821747529651465 0.522560700515155 0.6130848210061531 0.43115674427980505 0.9402569462049714 1.0 13.480455127439319 -4.903118797905593 1.4816709735057343 0.5793483337453843 1.545601147744991 0.5386450869503534 0.20912942213007588 0.6433741085058489 1.569060253273173 0.05933611343393575 0.8626957059222486 1.24991707827517e-05 4.903118797905593 0.9662528139996066 SSPSGNTQSS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPSGNTQSSPK 12 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 SSPSGNTQS(0.116)S(0.884)PK 123.95 0.0018170000000000003 0.0 3345.5 5433.2 4156.9 4321.2 12294.0 10728.0 4976.7 6507.4 9984.5 12932.0 True False 3911.8270733630648 5972.572189232117 4256.016261131036 4079.0971735194207 9885.078953217428 10165.404794435352 4505.270947812192 6336.587645160232 10130.50442368179 15276.469230344326 0.25606879537274424 0.3909654841819426 0.278599471969421 0.2670183215776673 0.647078772206228 0.665428944421487 0.2949157216814978 0.4147939913087762 0.6631443608421717 1.0 13.899023518964883 -14.522878744725203 0.122767618001814 2.9125273210347435 0.15960136325057492 0.662823665826569 0.13594798322054946 102.497748826238 0.8068062347750413 48.262496383498316 1.3355637516965757 3.000000003834735e-15 14.522878744725203 -2.7529259577841687 SSPST(ph)GSLDSGNESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSPSTGSLDSGNESK 15 0 A0A0U1RQT1;A0A087X1H5;Q15057 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 S(0.001)SPS(0.166)T(0.733)GS(0.1)LDSGNESK;S(0.003)SPS(0.013)T(0.837)GS(0.123)LDS(0.023)GNES(0.001)K;S(0.009)SPS(0.253)T(0.675)GS(0.062)LDS(0.001)GNESK 224.67 7.2403e-24 32063100.0 129378.0 136713.0 128356.0 161912.0 176973.0 134259.0 163725.0 157361.0 126524.0 121535.0 True False 151279.14006802195 150284.96313525905 131416.49383284056 152840.59556578632 142296.41106130998 127218.22169053824 148215.782733649 153230.4404877615 128374.17414010875 143568.33342946952 1.0537082687690353 1.0467835040314735 0.9153584964988204 1.0645843126741592 0.9911406482350483 0.8861161695732607 1.0323709915213484 1.0672997089782243 0.8941677532474446 1.0 17.131378046423393 -5.043950562995859 24.431200721092114 0.9852255838407924 1.051977209569231 0.16284446359640348 0.06205525090818278 555.4428597410358 308758.9099213848 0.01555261485027229 0.04115507738113229 9.037523446253454e-06 5.043950562995859 0.06675162572843862 SSPST(ph)GSLDSGNESK ddPTM_PC-9_Lapatinib_30min_R1 2 SSPSTGSLDSGNESK 15 0 A0A0U1RQT1;A0A087X1H5;Q15057 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 SSPS(0.011)T(0.83)GS(0.079)LDS(0.079)GNESK;SSPS(0.002)T(0.929)GS(0.067)LDS(0.001)GNESK 222.88 8.838900000000002e-24 30556000.0 69315.0 97157.0 106173.0 101381.0 106659.0 94553.0 100568.0 101280.0 103750.0 92169.0 True False 68326.55538918577 96932.03893580809 97443.86577963193 108836.89693710183 100385.52731966208 90509.1886038083 105774.9189569967 105985.83854081787 92064.58246406572 108100.28884252756 0.6320663535757874 0.896686215862119 0.9014209566227976 1.006814117727727 0.9286332940876433 0.8372705528627712 0.9784887726903461 0.9804399199636751 0.8516589867597721 1.0 16.7220108523764 -4.696273062050482 2.6538553713145343 0.9346972436798215 0.5255441452932194 0.7240298652002659 0.055822262257252994 0.3611687130525355 2.681151954513432 0.014271146912535969 0.36330401379718014 2.012458521499773e-05 4.696273062050482 -0.4091530983866022 SSPSTGS(ph)LDSGNESK ddPTM_PC-9_AZD4547_30min_R2 1 SSPSTGSLDSGNESK 15 0 A0A0U1RQT1;A0A087X1H5;Q15057 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 SSPS(0.001)T(0.203)GS(0.726)LDS(0.011)GNES(0.059)K 104.78 0.0011154000000000001 17141000.0 33151.0 32875.0 43049.0 45100.0 42662.0 54674.0 39937.0 46758.0 41365.0 41267.0 True False 43692.32841636408 43501.20084433597 42478.14213228307 34702.89178805405 36739.11769972349 51255.22613697126 43491.315631779464 39532.62549194895 43551.46945167878 39822.254890697244 1.0971836862651119 1.0923841696994951 1.0666935423138548 0.8714446704061674 0.9225775336068677 1.2871000468872202 1.0921359363288927 0.9927269462881181 1.0936464941831485 1.0 15.28128729391582 SSPSTGS(ph)LDSGNESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPSTGSLDSGNESK 15 0 A0A0U1RQT1;A0A087X1H5;Q15057 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 SSPS(0.002)T(0.176)GS(0.778)LDS(0.044)GNESK 184.92 4.5705e-07 6712100.0 73872.0 90961.0 88049.0 106220.0 115060.0 80322.0 96005.0 120570.0 84596.0 68597.0 True False 86377.07056149338 99991.00693969331 90148.4220876919 100268.83776988635 92514.8189651212 76109.77292120032 86910.71138399142 117405.16525447456 85833.05646009145 81033.0930864467 1.0659480870284157 1.233952736236073 1.1124889678285008 1.2373813457042646 1.1416918130772291 0.9392430922019213 1.0725335547943906 1.4488545455031054 1.059234606391294 1.0 16.306223589786875 -1.5228791856265584 24.999994780472573 1.1422258972678079 5.0202092038986734e-08 0.0 0.13833552573110341 0.0 0.0 0.031571068963096145 0.0 0.029999969581976104 1.5228791856265584 -1.1422258470657158 SSPSTGS(ph)LDSGNESKEK ddPTM_PC-9_AZD4547_30min_R2 1 SSPSTGSLDSGNESKEK 17 1 A0A0U1RQT1;A0A087X1H5;Q15057 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 S(0.008)S(0.008)PS(0.086)T(0.366)GS(0.533)LDSGNESKEK 77.969 0.0034616 4161500.0 16106.0 6312.6 13209.0 30054.0 23754.0 16022.0 12919.0 15904.0 12946.0 20819.0 True False 21227.372974388694 8353.024500378866 13033.840029392724 23125.514629671303 20456.167123886185 15020.141807194543 14068.765972580793 13446.402237562697 13630.299130217174 20090.13314681041 1.0566068835516322 0.415777458483645 0.648768225384411 1.1510881715257721 1.0182195894074444 0.7476377432361219 0.7002823659640308 0.6693037890442006 0.678457381571967 1.0 14.29419950507444 -10.625014776311891 14.209131087079784 0.9999999939527989 0.7826323520820802 0.0824767118616414 0.2122562435084225 0.0 0.0 0.21633972664940002 0.05247009082310167 2.371293024089923e-11 10.625014776311891 -0.21736764187071878 SSPSTGSLDS(ph)GNESK ddPTM_PC-9_AZD4547_30min_R2 1 SSPSTGSLDSGNESK 15 0 A0A0U1RQT1;A0A087X1H5;Q15057 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 SSPS(0.001)T(0.09)GS(0.289)LDS(0.426)GNES(0.194)K 120.21 8.5146e-05 14800000.0 20418.0 17379.0 25076.0 23350.0 22462.0 19678.0 23050.0 31315.0 22094.0 23317.0 True False 26910.499279216972 22996.421885132015 24743.47585563266 17967.018253903814 19343.539022342808 18447.531549243162 25101.405346233227 26475.986297112406 23261.84373420504 22500.678927142457 1.195986101857352 1.0220323555389053 1.099676855785215 0.7985100499447726 0.8596869047808505 0.819865552011855 1.11558435314383 1.1766749964675314 1.033828526220353 1.0 14.457680912993721 -9.69975046293962 13.21608319706055 0.9999999435853785 1.007575533970006 0.0 0.1363651013569358 0.0 0.0 0.1446272665603329 0.03507726449250669 1.9964090828426514e-10 9.69975046293962 0.0075755903846276285 SSPSVLIHS(ph)LGK ddPTM_PC-9_AZD4547_30min_R2 2 SSPSVLIHSLGK 12 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 SSPSVLIHS(1)LGK;SSPSVLIHS(1)LGK 75.998 0.010844 26315800.0 80038.0 87265.0 186672.0 269290.0 239970.0 241290.0 184237.0 253280.0 226694.0 245200.0 True False 105488.4191061791 115471.70468991564 184196.60731068192 207209.35098902593 206654.30768371545 226202.09815615873 200633.73608563916 214141.39579538954 238676.58203502622 236615.62263307182 0.44582186895479725 0.48801386571579713 0.7784634220721853 0.8757213436847016 0.8733755843509182 0.9559897002529638 0.8479310615798559 0.9050179925248053 1.0087101577614357 1.0 17.852185805727274 -5.342669296427812 1.6397339226236414 0.9222063211986979 0.4109008435378809 0.9305567749230974 0.049467020524091944 0.10498320364058558 0.4957802405587893 0.01455255398103632 0.05956297574207929 4.542874126277593e-06 5.342669296427812 -0.511305477660817 down SSPSVLIHS(ph)LGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSPSVLIHSLGK 12 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 SSPSVLIHS(1)LGK;SSPSVLIHS(1)LGK 80.387 0.008132200000000001 21599000.0 68147.0 82178.0 124681.0 161467.0 172473.0 154822.0 163306.0 157741.0 161978.0 120755.0 True False 79682.9411353977 90336.08874451811 127653.86789532567 152420.52747307715 138678.1537577897 146702.86177144587 147836.4734469466 153600.46589040468 164346.62181773045 142646.9256039463 0.558602583252543 0.6332845125266338 0.8948939302747522 1.0685160358539159 0.9721776559196534 1.0284333935016639 1.0363803693702371 1.076787776813855 1.1521217237729506 1.0 17.122089128024953 -5.334406806331094 1.9801585987326098 1.0486109966727761 0.5518350872911005 0.936333588823999 0.04676446672049721 0.08382170284519927 0.6049809058654215 0.013989129720696963 0.049028205464701165 4.630130093910948e-06 5.334406806331094 -0.4967759093816756 SSPSVLIHS(ph)LGK ddPTM_PC-9_Lapatinib_30min_R1 2 SSPSVLIHSLGK 12 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 SSPSVLIHS(1)LGK;SSPSVLIHS(1)LGK 86.539 0.0051385 21529000.0 177076.0 132821.0 200657.0 141896.0 159971.0 188279.0 158912.0 156545.0 194988.0 120683.0 True False 174550.8637682384 132513.46113499816 184159.7560184194 152331.50519117946 150561.82029508692 180226.74606978556 167139.68579761224 163818.65219561948 173026.39812533252 141542.8957500103 1.2332011638120361 0.9362070800716151 1.3010879496465722 1.076221483134157 1.0637186663257592 1.2733012498776184 1.18084122069122 1.1573781313966622 1.222430820059861 1.0 17.11087981447215 -6.7318720012972175 24.999936531166455 1.177504811806609 1.11915701576639 0.03317592509859679 0.11296548125937722 652.8835665822664 552027.4971768442 0.03519731352025789 0.03519243093698705 1.8540779914179316e-07 6.7318720012972175 -0.058347796040219 SSPVNNHHS(ph)PGQTPTLGQPEAR ddPTM_PC-9_AZD4547_30min_R2 1 SSPVNNHHSPGQTPTLGQPEAR 22 0 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79;E7EWM2;E7EMW0;Q96L14 H0Y2V6 CEP170;CEP170P1 Centrosomal protein of 170 kDa;Cep170-like protein 1 SSPVNNHHS(0.994)PGQT(0.004)PT(0.001)LGQPEAR 70.983 0.00095452 4243800.0 3718.4 4809.3 11201.0 18132.0 16663.0 11116.0 8370.4 12539.0 9817.5 9323.1 True False 4900.773852475287 6363.812174012622 11052.467421396617 13951.947536607458 14349.630074316556 10420.91476274963 9115.349384386582 10601.38566755524 10336.43300717651 8996.701106730783 0.5447300954356288 0.7073495160633496 1.2285022354613777 1.5507848233581376 1.5949879743788573 1.15830398710849 1.0131879759312037 1.1783636626122802 1.148913683421518 1.0 13.135180378391258 -5.210840030071109 3.763043789164644 1.256587412889065 0.586006557793922 0.626441303679468 0.18889127815894452 0.1553523380785477 4.543677596853568 0.05522287424173854 0.16176094576800598 6.154035113876726e-06 5.210840030071109 -0.6705808550951431 SSPVNNHHS(ph)PGQTPTLGQPEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSPVNNHHSPGQTPTLGQPEAR 22 0 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79;E7EWM2;E7EMW0;Q96L14 H0Y2V6 CEP170;CEP170P1 Centrosomal protein of 170 kDa;Cep170-like protein 1 SSPVNNHHS(0.995)PGQT(0.004)PTLGQPEAR 70.027 0.0016438 4379400.0 3366.8 6393.1 10169.0 11871.0 9676.1 11608.0 6136.9 11069.0 10663.0 6711.3 True False 3936.732742668888 7027.764717474015 10411.467526147264 11205.906356301277 7780.137665465042 10999.256045283886 5555.568404691591 10778.450478574938 10818.926202585895 7928.00556337843 0.49656029012564085 0.8864480052760221 1.31325179364664 1.4134584375248604 0.9813486637047242 1.3873925740027706 0.7007523342761314 1.3595412354859426 1.364646646132717 1.0 12.952742259579987 -4.9293117736522225 2.954783640579063 1.1915484620658046 0.4761749547948678 0.49035530799574367 0.2207323101262209 0.24982477306919745 3.8374516934220138 0.056266827286603045 0.3626990620107628 1.1767608908004143e-05 4.9293117736522225 -0.7153735072709367 SSPVNNHHS(ph)PGQTPTLGQPEAR ddPTM_PC-9_Lapatinib_30min_R1 2 SSPVNNHHSPGQTPTLGQPEAR 22 0 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79;E7EWM2;E7EMW0;Q96L14 H0Y2V6 CEP170;CEP170P1 Centrosomal protein of 170 kDa;Cep170-like protein 1 SSPVNNHHS(0.996)PGQT(0.002)PT(0.002)LGQPEAR;SSPVNNHHS(0.998)PGQT(0.001)PT(0.001)LGQPEAR 89.29700000000001 0.00041980000000000007 0.0 11404.7 12113.1 16351.6 15069.9 15727.0 13952.900000000001 13199.7 11587.7 17894.9 10755.4 True False 11242.06688663416 12085.052861176648 15007.234567001326 16178.190717712689 14801.968780471647 13356.166992798528 13883.115879371864 12126.106844978633 15879.387920349009 12614.456559330347 0.8912050102006898 0.9580319853127464 1.189685381721906 1.2825119054174718 1.1734131162014503 1.0587984452583945 1.1005718569067604 0.9612865039365882 1.2588245752532032 1.0 13.622790434769968 -5.124597341659907 4.580849803959276 1.1299191423982287 0.9062217688446392 0.41076974856267856 0.09862534048885063 0.21412443096317255 6.864704473053891 0.02623503704150154 0.07740237168257083 7.50589799977076e-06 5.124597341659907 -0.22369737355358943 SSPYGT(ph)LKPEEMSGPGLAEPK ddPTM_PC-9_Lapatinib_30min_R1 1 SSPYGTLKPEEMSGPGLAEPK 21 1 Q5JSZ5;A0A494C0D3;Q5JSZ5-5;A0A494C065;H0Y412 Q5JSZ5 PRRC2B Protein PRRC2B 1 S(0.09)S(0.299)PY(0.247)GT(0.363)LKPEEMS(0.001)GPGLAEPK 54.17100000000001 0.012334999999999999 15005000.0 49635.0 41283.0 37625.0 46596.0 47192.0 53803.0 45297.0 45021.0 48283.0 39824.0 True False 48927.19579805581 41187.41174991996 34531.61773670006 50022.825279699304 44416.25934304178 51501.97111091878 47642.25702007682 47112.84001724095 42844.86009746974 46707.52533785553 1.0475227587876783 0.8818153274444273 0.7393159343578595 1.0709799955759332 0.9509443932591153 1.1026482507558037 1.0200124428656834 1.0086777168444188 0.917301008511038 1.0 15.511367389719029 -5.7940642443461225 24.99996132939236 1.0122489244565827 0.888777229896966 0.296778108472757 0.0849736371888225 225.6108426622769 172881.37125195735 0.024057754197063127 0.035686272966493085 1.6067035588700365e-06 5.7940642443461225 -0.12347169455961671 SSQAEACS(ph)ESR ddPTM_PC-9_Lapatinib_30min_R1 1 SSQAEACSESR 11 0 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 S(0.001)S(0.002)QAEACS(0.997)ESR 81.278 0.042809 0.0 2991.3 2232.6 4389.9 3321.4 3853.4 3418.9 2465.2 2333.8 3798.1 2726.6 True False 2948.643513462765 2227.4305518705346 4028.979367504042 3565.6668358655957 3626.7505880758868 3272.681616845161 2592.8359936837596 2442.2368679557726 3370.3179822339093 3197.8891770338737 0.9220593179522591 0.6965315020505292 1.2598871144249677 1.1150063802939054 1.134107652673503 1.0233880649612315 0.8107960752062969 0.7637027841662142 1.053919568707496 1.0 11.642904227697342 -7.203933561974637 10.280757517333825 0.8874711393453768 1.030043851384378 0.1106360625994629 0.1598044071012893 1.3983349926247357 246.02986647396096 0.06494243343266276 0.05026561565562613 6.252683385140635e-08 7.203933561974637 0.14257271203900113 SSQASQNRHS(ph)MEISPPVLISSSNPTAAAR ddPTM_PC-9_AZD4547_30min_R2 2 SSQASQNRHSMEISPPVLISSSNPTAAAR 29 1 Q7Z6J0;H0YA90;Q7Z6J0-3 Q7Z6J0 SH3RF1 E3 ubiquitin-protein ligase SH3RF1 1 S(0.011)S(0.011)QAS(0.034)QNRHS(0.894)MEIS(0.046)PPVLIS(0.001)S(0.001)S(0.001)NPT(0.001)AAAR;S(0.008)S(0.006)QAS(0.075)QNRHS(0.862)MEIS(0.049)PPVLISSSNPT(0.001)AAAR 64.422 0.0028553000000000003 7009900.0 6968.4 4902.0 14250.599999999999 25192.1 22453.0 14852.2 9151.0 16352.7 11694.099999999999 15847.0 True False 9184.20624827581 6486.47563616532 14061.627732823365 19384.450559065106 19335.78851699151 13923.489586120008 9965.421272164001 13825.765962662947 12312.226252021688 15292.201353451392 0.6005810436312997 0.42416886138511034 0.9195293344505766 1.2676036700687379 1.264421522453175 0.9104960930283283 0.6516668883590683 0.9041056707994839 0.8051310578148296 1.0 13.900508481023069 -5.311792617211493 6.307137355531862 0.9720111438259479 0.5128194985315447 0.4990718245630469 0.18166425486221693 0.178163808410383 17.17473040206567 0.05430468676291757 0.11657893967502671 4.877613486025591e-06 5.311792617211493 -0.45919164529440315 SSQCHTGS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSQCHTGSSPR 11 0 O15226;O15226-2 O15226 NKRF NF-kappa-B-repressing factor 1 SSQCHT(0.007)GS(0.803)S(0.19)PR 71.558 0.02943 445560.0 0.0 0.0 599.99 607.64 2428.8 3673.8 0.0 1164.0 2368.2 1055.4 True False 0.0 0.0 614.2960370747464 573.5959007954598 1952.8940752866858 3481.139460644723 0.0 1133.4462333599447 2402.8304448057684 1246.735665458197 0.0 0.0 0.49272356129234657 0.4600781999644274 1.566405878481838 2.792203317104387 0.0 0.9091311532692726 1.9272974307049173 1.0 10.283939900144553 -6.110805634284983 3.5923498168786914 1.3608026795977535 0.1801931419735607 0.3934940252454162 0.6911984242723836 0.2778025775395134 6.538452460379501 0.22096974478928816 0.29807125837220544 7.748084807941015e-07 6.110805634284983 -1.1806095376241927 SSQCHTGS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSQCHTGSSPR 11 0 O15226;O15226-2 O15226 NKRF NF-kappa-B-repressing factor 1 SSQCHT(0.19)GS(0.621)S(0.19)PR 73.415 0.014053 605970.0 3160.0 690.31 2977.5 2658.2 3482.7 2854.2 6770.1 7898.2 3788.4 2245.1 True False 3114.937820526973 688.7116296075196 2732.701443482378 2853.692895495252 3277.8544332516435 2732.132519465166 7120.622651646288 8265.179205796683 3361.7104983794356 2633.162543592292 1.1829645033144893 0.2615530253851875 1.037802033958105 1.0837511350902407 1.244835584202041 1.0375859728499153 2.7042093048809583 3.138879225632958 1.2766817250078388 1.0 11.362580865520647 -7.214696697626234 9.4694675335099 2.2076705605654667 0.96123157053028 0.38387471506630866 0.6391116599979555 0.4531895761599157 89.60511337295364 0.24058917024369006 0.18584925438442934 6.09962734009163e-08 7.214696697626234 -1.2464389900351867 SSQDGDT(ph)PAQASPPEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSQDGDTPAQASPPEEK 17 0 A0A0C4DGE6;E9PNT2;E9PIR1;A0A0G2JRG8;A0A0G2JNY3;Q6ZUM4-2;Q6ZUM4-3;Q6ZUM4;E9PNX6 A0A0C4DGE6 ARHGAP27 Rho GTPase-activating protein 27 1 SSQDGDT(0.521)PAQAS(0.479)PPEEK 216.53 5.381900000000001e-22 9543500.0 70299.0 69551.0 68330.0 78586.0 82974.0 72698.0 76687.0 73019.0 66672.0 56258.0 True False 82199.23223146037 76455.56363345405 69959.246342968 74183.0811992496 66715.84033384288 68885.58890248516 69422.6521941996 71102.3286200257 67646.95186896816 66457.13006191711 1.2368760455782033 1.1504493733361876 1.0526973746502148 1.116254661164789 1.0038928896219974 1.03654173507501 1.044623084528621 1.0698976701789669 1.017903598995962 1.0 16.0201363714232 -1.522881163497816 0.5771858572519365 1.032289615344871 12.476303811608961 0.8262535875822961 0.02959818615198489 58.42011607481955 0.48960864065990534 0.013550130234677785 837.0560375291664 0.02999983295591953 1.522881163497816 11.44401419626409 SSQDGDTPAQAS(ph)PPEEK ddPTM_PC-9_AZD4547_30min_R2 2 SSQDGDTPAQASPPEEK 17 0 A0A0C4DGE6;E9PNT2;E9PIR1;A0A0G2JRG8;A0A0G2JNY3;Q6ZUM4-2;Q6ZUM4-3;Q6ZUM4;E9PNX6 A0A0C4DGE6 ARHGAP27 Rho GTPase-activating protein 27 1 SSQDGDTPAQAS(1)PPEEK;SSQDGDT(0.029)PAQAS(0.971)PPEEK 149.42 1.2975e-11 12276000.0 57689.0 46927.0 43712.0 62877.0 58306.0 59594.0 54756.0 68045.0 55425.0 59310.0 True False 76032.9019942574 62095.235042499 43132.35031908656 48381.67908996619 50211.21833481972 55867.577759203064 59629.17792357256 57530.20876854589 58354.65234761991 57233.57495255902 1.3284667619885908 1.084944197422052 0.7536197128143579 0.8453373588854063 0.8773035473747683 0.976132939546617 1.041856602055686 1.0051828636640774 1.0195877576403387 1.0 15.804574103599492 -4.8919148526258365 3.658454610525094 0.9381524951547753 1.3318375000446325 0.6518738633549435 0.08692765213414293 0.16251107292137706 3.7519745675453713 0.024662657378300475 0.14369205554898365 1.2825820198506708e-05 4.8919148526258365 0.39368500488985725 SSQDGDTPAQAS(ph)PPEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSQDGDTPAQASPPEEK 17 0 A0A0C4DGE6;E9PNT2;E9PIR1;A0A0G2JRG8;A0A0G2JNY3;Q6ZUM4-2;Q6ZUM4-3;Q6ZUM4;E9PNX6 A0A0C4DGE6 ARHGAP27 Rho GTPase-activating protein 27 1 SSQDGDTPAQAS(1)PPEEK;SSQDGDT(0.059)PAQAS(0.941)PPEEK 225.69 9.570599999999998e-67 6131900.0 61537.0 62052.0 55788.0 74630.0 71939.0 68177.0 68304.0 68969.0 61230.0 51770.0 True False 71953.99868884863 68212.11247261858 57118.19749716816 70448.72305372439 57843.069368432436 64601.67810125081 61833.75064186389 67158.63682869588 62125.37291422065 61155.491188905515 1.1765746180761953 1.1153881874959617 0.9339831368655612 1.1519607100548446 0.9458360687474292 1.0563512261180314 1.0110907367396211 1.0981620051296297 1.0158592745550719 1.0 15.900194424587088 -5.023279236722277 11.045223715062441 1.0317335316349228 1.1614142615366103 0.38723611487367826 0.06190472223501778 0.6058620269903479 289.8803374797801 0.014433140382080809 0.04068248470442238 9.478088581760757e-06 5.023279236722277 0.12968072990168755 SSQKS(ph)PELGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSQKSPELGK 10 1 Q9UEG4 Q9UEG4 ZNF629 Zinc finger protein 629 1 SSQKS(1)PELGK 109.15 0.0092953 6959200.0 24290.0 17982.0 19521.0 25895.0 28075.0 27495.0 29585.0 23935.0 22052.0 20944.0 True False 28401.81725063185 19767.134121102106 19986.454673804772 24444.187102722717 22573.905288073824 26053.113797818783 26782.494623148636 23306.731611228766 22374.46878171473 24740.98140738723 1.1479664764693434 0.7989632179748529 0.8078278846221177 0.9880039397072626 0.9124094520087892 1.0530347753319023 1.0825154500601923 0.9420293895160432 0.9043484740275542 1.0 14.594615108784039 -6.737062176833664 24.987131679225946 0.9981455777681316 0.9200170780672281 0.08666481574841844 0.10293830133746483 530.965701269372 544249.3347160299 0.03466121097983873 0.03464510764818776 1.832052113364672e-07 6.737062176833664 -0.07812849970090352 SSQNFQTLPSSPLLVPQES(ph)LASSEVK ddPTM_PC-9_Lapatinib_30min_R1 1 SSQNFQTLPSSPLLVPQESLASSEVK 26 0 D6RAS1;Q9Y4E5-4 D6RAS1 ZNF451 1 SSQNFQT(0.003)LPS(0.015)S(0.015)PLLVPQES(0.958)LAS(0.006)S(0.003)EVK 51.46 0.0094227 1394700.0 3331.9 4450.6 3886.5 3741.2 5597.4 3710.0 3930.9 6175.1 4361.3 4870.2 True False 3284.3864950043726 4440.2949091440505 3566.966972323847 4016.3403282773434 5268.171936911808 3551.331948432406 4134.422767958582 6462.017689310864 3870.0844674749856 5712.007580866411 0.5749968725542532 0.7773615224212528 0.6244681789765414 0.7031398805791037 0.9222977845055168 0.621730958538702 0.7238125491653256 1.1313041164295319 0.6775348969141182 1.0 12.479782178747433 -3.8242133071501447 0.09296366625234635 1.1887999309577773 5.291105042358213e-18 0.32217256281063045 0.14324317673727857 104.83988111102413 1.185476329164843 3.047962173542878 16.669725427787675 0.00014989484343610763 3.8242133071501447 -1.1887999309577773 SSQPLASK ddPTM_PC-9_Lapatinib_30min_R1 1 SSQPLASK 8 0 P17096;P17096-3;A0A669KAX1;A0A1W2PRV2;P17096-2 P17096;P17096-2 HMGA1 High mobility group protein HMG-I/HMG-Y 0 92.051 0.03808 3940000.0 39799.0 39379.0 42893.0 33943.0 42687.0 36286.0 33470.0 53856.0 53162.0 38587.0 False True 39231.458961757264 39287.82034493856 39366.503111768114 36439.28145052866 40176.23458587104 34734.13236679736 35202.91283003225 56358.34637099417 47174.33573932206 45256.711536054456 0.8668649937259122 0.868110364440406 0.8698489522467001 0.8051685642581154 0.8877409167005876 0.7674912999174914 0.7778495528113506 1.2453036126165602 1.0423721507414407 1.0 15.465844138193436 -7.750974095757136 24.999906566237936 1.1078784255676553 0.8356762863822893 0.7420426881636991 0.07045683931631909 90.60412645035781 216440.19635579307 0.032324054856293236 0.01840513025862915 1.7742953086356134e-08 7.750974095757136 -0.27220213918536595 SSQPS(ph)PTAVPAS(ph)DSPPTKQEVK ddPTM_PC-9_Lapatinib_30min_R1 1 SSQPSPTAVPASDSPPTKQEVK 22 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 2 S(0.011)S(0.014)QPS(0.967)PT(0.01)AVPAS(0.53)DS(0.324)PPT(0.144)KQEVK 102.05 0.0002301 7544600.0 83808.0 88943.0 97424.0 91167.0 96533.0 111490.0 101580.0 95186.0 88954.0 62501.0 True False 82612.88255149523 88737.05794814166 89414.17478751554 97871.7253041967 90855.11873118019 106721.83259588382 106839.31536524271 99608.68905357717 78935.06379285299 73304.21457265239 1.1269868046893394 1.2105314607824311 1.2197685400325304 1.3351445871805265 1.2394255809279964 1.4558758076605673 1.4574784818048 1.3588398652693319 1.076814808712258 1.0 16.161608526998158 -5.211584643318721 1.3857370750925837 1.3034638951437303 1.1254809225493292 0.06083452283056123 0.14199963894195358 1.389224795468079 3.9796907296472215 0.043239659160400214 0.27698786215650123 6.1434928431732065e-06 5.211584643318721 -0.1779829725944011 SSQPS(ph)PTAVPASDS(ph)PPTKQEVK ddPTM_PC-9_Lapatinib_30min_R1 1 SSQPSPTAVPASDSPPTKQEVK 22 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 2 S(0.014)S(0.017)QPS(0.634)PT(0.335)AVPAS(0.013)DS(0.941)PPT(0.046)KQEVK 97.295 0.00044453 7843700.0 83454.0 95654.0 89173.0 81134.0 94005.0 91355.0 87625.0 85824.0 88268.0 49194.0 True False 82263.9306564107 95432.5190399643 81841.54015773449 87100.86501508992 88475.81072094085 87447.95960890624 92161.79374758218 89811.69635591573 78326.32833675329 57697.117353115354 1.4257892669566594 1.6540257714419666 1.4184684419648126 1.5096224735461052 1.533452879100616 1.515638278316594 1.5973379256287212 1.5566062998651067 1.3575431829182028 1.0 15.816211620703513 -8.630846862254554 2.7936862520932078 1.0004007459736042 1.5280540098833244 0.8503332125836893 0.06719564317689217 0.146962022062753 2.523554453204809 0.06187234552433104 0.01656372751645182 2.339662087766758e-09 8.630846862254554 0.5276532639097202 SSQPS(ph)PTAVPASDSPPTK ddPTM_PC-9_Lapatinib_30min_R1 1 SSQPSPTAVPASDSPPTK 18 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 SS(0.002)QPS(0.993)PT(0.005)AVPASDSPPTK 137.12 9.815799999999999e-05 6611600.0 20798.0 32495.0 28055.0 28199.0 28622.0 29652.0 33936.0 35581.0 30924.0 16560.0 True False 20501.416706113923 32419.75982398685 25748.42619543176 30272.848529106395 26938.510233017078 28383.85308218805 35693.040029876734 37234.22315482665 27441.013475843567 19422.37393518702 1.055556688102479 1.6691965633126233 1.3257095286783656 1.5586585156957484 1.386983399810528 1.4613997844396223 1.8377279805746383 1.9170788946334905 1.4128557903073518 1.0 14.245431927124681 -7.025128829588253 23.31120967637231 1.6227996775728677 1.419513041662405 0.021124493388590238 0.28085140823800037 747.9288965902944 693826.702846129 0.10137670892702214 0.07897129711198844 9.437808705717305e-08 7.025128829588253 -0.2032866359104626 SSQPSPT(ph)AVPASDS(ph)PPTKQEVK ddPTM_PC-9_Lapatinib_30min_R1 1 SSQPSPTAVPASDSPPTKQEVK 22 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 2 S(0.017)S(0.017)QPS(0.336)PT(0.629)AVPAS(0.138)DS(0.859)PPT(0.003)KQEVK 108.71 8.9895e-05 7885600.0 86223.0 86201.0 96669.0 89395.0 110800.0 101970.0 93895.0 94920.0 92500.0 66725.0 True False 84993.44420863813 86001.40688067382 88721.24797313115 95969.40651297774 104282.96184118131 97608.9808036799 98756.42366823647 99330.3297224962 82081.67593181766 78258.32734452607 1.086062622249275 1.0989425636719714 1.133697217710045 1.226315585438979 1.3325477988059196 1.2472663819399576 1.261928628163354 1.2692621104103377 1.0488554856336196 1.0 16.255956654654682 -5.626644301160455 3.5725523614721233 1.2195096733185795 1.0964027403500038 0.13932380142431444 0.09767743250002257 0.34715077835772024 8.525612618218622 0.026646428210522193 0.04965568416524543 2.3624123201483005e-06 5.626644301160455 -0.12310693296857567 SSQPSPT(ph)AVPASDSPPTK ddPTM_PC-9_AZD4547_30min_R2 2 SSQPSPTAVPASDSPPTK 18 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 SSQPS(0.036)PT(0.964)AVPASDSPPTK;SSQPS(0.058)PT(0.94)AVPAS(0.002)DSPPTK 188.56 1.9528999999999998e-10 14156600.0 39322.0 56270.0 74708.0 89029.0 87340.0 96250.0 77217.0 90214.0 72391.0 76257.0 True False 51825.57805159022 74458.17708017593 73717.32310666004 68504.73953433843 75214.34859814022 90231.47228451341 84089.1634108498 76273.49921148657 76217.44047084439 73587.26564082429 0.7042737299758933 1.011835083580935 1.00176739092971 0.9309319885414221 1.0221109310577952 1.2261832464998583 1.1427135208595023 1.0365040547066071 1.03574225522739 1.0 16.16716850742997 -4.1365779361030715 0.9278334928771376 1.0706469894748412 6.400603843786327e-36 0.6181745237602838 0.07955031282894394 4.480296583125475 1.3033047777994962 0.02904041936035114 6.442894790518961 7.301667693963544e-05 4.1365779361030715 -1.0706469894748412 SSQPSPT(ph)AVPASDSPPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSQPSPTAVPASDSPPTK 18 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 SSQPS(0.024)PT(0.976)AVPASDSPPTK 114.99 0.00033151 5290500.0 19461.0 18644.0 18264.0 20654.0 29423.0 19286.0 27335.0 16530.0 23914.0 21183.0 True False 22755.362927729366 20494.853106096518 18699.483026605718 19496.823341171472 23657.774364772795 18274.60820893737 24745.630911737946 16096.105014982724 24263.697009156822 25023.310215464266 0.9093666158391258 0.8190304531904341 0.7472825483756159 0.779146450781022 0.9454294480253225 0.7303033871851121 0.9889031746265642 0.6432444339452509 0.969643776152445 1.0 14.610985028987146 -8.495164041219956 24.76320526246519 1.0000001295213723 0.8222219608349561 0.30736736456124814 0.09925748483989087 584.527322198644 522278.3113908597 0.08816569288374697 0.022764284030179858 3.1976870548195714e-09 8.495164041219956 -0.17777816868641616 SSQPSPT(ph)AVPASDSPPTK ddPTM_PC-9_Lapatinib_30min_R1 1 SSQPSPTAVPASDSPPTK 18 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 SSQPS(0.243)PT(0.757)AVPASDSPPTK 162.82 2.7751e-06 7377800.0 35090.0 48811.0 51459.0 41275.0 57402.0 59163.0 61031.0 62060.0 48223.0 28632.0 True False 34589.61016528211 48697.98112843889 47228.23965748436 44310.501189363684 54025.72721667414 56632.736405689044 64190.886553023505 64943.5341611686 42791.617929297725 33581.00305025812 1.0300350502787092 1.4501645783348505 1.4063975273996867 1.3195109485874363 1.6088181504232604 1.6864516024411527 1.911523799838674 1.9339366981972688 1.2742805170308575 1.0 15.035357703154377 -6.284650424052175 4.374299550488007 1.6419800937652815 1.3171756865874873 0.14648368331425698 0.2855818367756098 0.3234661638805884 15.381740967044657 0.08735902116762256 0.10436538294503289 5.192178039096345e-07 6.284650424052175 -0.32480440717779424 SSQPSPTAVPASDS(ph)PPTKQEVK ddPTM_PC-9_AZD4547_30min_R2 3 SSQPSPTAVPASDSPPTKQEVK 22 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 SSQPS(0.004)PT(0.012)AVPAS(0.069)DS(0.909)PPT(0.007)KQEVK;SSQPS(0.002)PT(0.007)AVPAS(0.024)DS(0.955)PPT(0.012)KQEVK;SSQPSPTAVPAS(0.001)DS(0.995)PPT(0.004)KQEVK 115.45 7.427899999999999e-07 50501000.0 85710.0 85990.0 135891.0 169122.0 153159.0 179811.0 135154.0 143505.0 124439.0 150325.0 True False 112963.99712125004 113784.58587389976 134088.99655039798 130133.53580885318 131895.51656677935 168567.38974494144 147182.44417200878 121329.59966684051 131016.59149274648 145062.1675053687 0.7787281760909114 0.7843849835601597 0.9243553909080766 0.8970880419530266 0.9092344257292166 1.1620355096286756 1.0146163310744796 0.8363972616247454 0.9031754712192454 1.0 17.146311785232555 -5.358337245651967 1.1958966605378365 0.969880290440513 0.749169664167037 0.42014584937777655 0.08348730189195137 0.7605864827290831 1.7059831553463323 0.030402752427989486 0.16269071375659416 4.381902947303084e-06 5.358337245651967 -0.22071062627347604 SSQPSPTAVPASDS(ph)PPTKQEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSQPSPTAVPASDSPPTKQEVK 22 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 SSQPSPTAVPAS(0.471)DS(0.527)PPT(0.002)KQEVK;SSQPSPTAVPAS(0.07)DS(0.597)PPT(0.333)KQEVK;SSQPSPTAVPAS(0.012)DS(0.642)PPT(0.346)KQEVK 118.63 5.4274e-07 38231400.0 72364.0 69717.0 70542.0 115204.0 130200.0 112866.0 130704.0 121016.0 117932.0 95421.0 True False 84613.79594585091 76638.04301639817 72223.98881202465 108749.49337640751 104688.24464852025 106947.10827076243 118322.7709049861 117839.45822705099 119656.53239457567 112720.07194777971 0.7506542045595065 0.6798970377866915 0.6407376039068193 0.9647748754701677 0.9287453675244246 0.9487849539371147 1.0497045367377158 1.0454168116716867 1.0615370477230484 1.0 16.78238491205108 -5.814221663366806 5.728336304581135 1.0011278192017639 0.6893391866640439 0.8976918224556025 0.0479279846870432 0.06072311276416106 4.264504169845631 0.015415392068293558 0.023557729901845476 1.5338339160431047e-06 5.814221663366806 -0.31178863253771993 SSQPSPTAVPASDS(ph)PPTKQEVK ddPTM_PC-9_Lapatinib_30min_R1 4 SSQPSPTAVPASDSPPTKQEVK 22 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 SSQPSPTAVPAS(0.011)DS(0.951)PPT(0.038)KQEVK;SSQPSPTAVPAS(0.001)DS(0.997)PPT(0.001)KQEVK;SSQPSPTAVPAS(0.119)DS(0.818)PPT(0.062)KQEVK;SSQPSPTAVPAS(0.002)DS(0.996)PPT(0.002)KQEVK 110.44 7.8884e-06 62461000.0 222673.0 242884.0 238932.0 221047.0 263407.0 288985.0 253934.0 281319.0 258025.0 178744.0 True False 219497.64218677263 242321.6170207484 219287.93326419152 237303.53377117505 247913.91813808703 276625.7852069379 267081.46001139557 294390.1077455011 228963.5073762944 209639.6622385911 1.0470234489166566 1.1558958568868611 1.046023118538608 1.1319591495100754 1.1825716350178812 1.319529817273364 1.2740025296712696 1.4042672297881087 1.092176475249759 1.0 17.67755216412582 -6.329474529765362 2.6597049747274313 1.2464919575593114 1.0920570602570772 0.1908251805169393 0.11202603674990587 0.3660689669988486 5.086620303681612 0.035517420510732534 0.04273010578169706 4.683014152205184e-07 6.329474529765362 -0.15443489730223425 SSQQPS(ph)TPQQAPPGQPQQGTFVAHK ddPTM_PC-9_AZD4547_30min_R2 2 SSQQPSTPQQAPPGQPQQGTFVAHK 25 0 E7ERS3;Q86VM9;H3BRH3 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 S(0.042)S(0.042)QQPS(0.544)T(0.371)PQQAPPGQPQQGTFVAHK;S(0.05)S(0.05)QQPS(0.45)T(0.45)PQQAPPGQPQQGTFVAHK 119.8 2.721e-09 67811000.0 81872.0 81305.0 124832.0 161674.0 157330.0 148289.0 98631.0 145617.0 113699.0 128590.0 True False 107905.59295660949 107585.2512440681 123176.64611622025 124402.55713840008 135487.44521348018 139016.4653880334 107408.9679264352 123115.23859577232 119708.89701889109 124088.1032397501 0.8695885434571077 0.8670069767784515 0.9926547581941129 1.0025341180213097 1.0918649062731298 1.1203045397465725 0.8655863464921435 0.9921598878653329 0.964708895482124 1.0 16.921005280318084 -5.286387109113158 4.385010255049709 1.0067830725750049 0.8660213775497548 0.410925884649067 0.06493733260707256 0.19786619548872955 9.459216841102217 0.018453358836956486 0.04448683803213108 5.171456677950408e-06 5.286387109113158 -0.14076169502525004 SSQQPST(ph)PQQAPPGQPQQGTFVAHK ddPTM_PC-9_AZD4547_30min_R2 2 SSQQPSTPQQAPPGQPQQGTFVAHK 25 0 E7ERS3;Q86VM9;H3BRH3 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 S(0.037)S(0.037)QQPS(0.254)T(0.673)PQQAPPGQPQQGTFVAHK;S(0.005)S(0.005)QQPS(0.252)T(0.738)PQQAPPGQPQQGTFVAHK 164.99 6.6485e-10 58516000.0 63271.0 63821.0 97402.0 123111.0 117583.0 111896.0 77646.0 117393.0 77570.0 99880.0 True False 83389.86188144458 84449.89016232308 96110.38583866371 94729.66099598944 101258.63008031923 104899.12543114704 84556.34357976678 99252.6092727741 81670.1918377063 96383.23160110613 0.8651905574878812 0.8761886145489429 0.9971691573533078 0.9828437937009604 1.0505834718158293 1.0883545165333839 0.8772930952316852 1.029770507006273 0.8473485530730951 1.0 16.556494553077343 -5.255533031336817 19.25150456240429 0.9874619800429688 0.8706890342688313 0.29920983552457836 0.06932231380522069 23.670340813660474 77132.23177363073 0.01759864313831513 0.043393844758727235 5.5522238670706055e-06 5.255533031336817 -0.11677294577413755 SSQQPST(ph)PQQAPPGQPQQGTFVAHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSQQPSTPQQAPPGQPQQGTFVAHK 25 0 E7ERS3;Q86VM9;H3BRH3 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 S(0.017)S(0.017)QQPS(0.21)T(0.757)PQQAPPGQPQQGTFVAHK;S(0.033)S(0.033)QQPS(0.248)T(0.685)PQQAPPGQPQQGTFVAHK;S(0.041)S(0.041)QQPS(0.243)T(0.676)PQQAPPGQPQQGTFVAHK;S(0.037)S(0.037)QQPS(0.236)T(0.69)PQQAPPGQPQQGTFVAHK 164.99 6.6485e-10 101090000.0 262229.0 253653.0 299664.0 326579.0 353454.0 314602.0 329001.0 267801.0 277518.0 235238.0 True False 306619.19044116605 278833.9935057236 306809.1262420489 308281.8374134031 284197.2259907695 298103.71729483106 297835.6435190302 260771.50750861398 281576.1757375259 277884.7872570164 1.1034040167070143 1.0034158266023727 1.1040875222805209 1.109387240864943 1.022716028452161 1.0727601184555458 1.0717954244956964 0.9384159171960201 1.013283881125509 1.0 18.084127331106984 -7.744040385451495 24.981616672964808 0.9818874294439227 1.0682717595501168 0.5290217120365455 0.03704765178255426 172.4602147843413 247620.44938139475 0.017005594198896738 0.009788669742702327 1.8028500843429492e-08 7.744040385451495 0.08638433010619406 SSQQPST(ph)PQQAPPGQPQQGTFVAHK ddPTM_PC-9_Lapatinib_30min_R1 4 SSQQPSTPQQAPPGQPQQGTFVAHK 25 0 E7ERS3;Q86VM9;H3BRH3 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 S(0.011)S(0.011)QQPS(0.404)T(0.573)PQQAPPGQPQQGTFVAHK;S(0.118)S(0.118)QQPS(0.194)T(0.57)PQQAPPGQPQQGTFVAHK;S(0.034)S(0.034)QQPS(0.249)T(0.684)PQQAPPGQPQQGTFVAHK;S(0.011)S(0.011)QQPS(0.264)T(0.713)PQQAPPGQPQQGTFVAHK 166.24 5.640399999999999e-10 117209000.0 244818.0 235747.0 290501.0 235770.0 250435.0 262421.0 223843.0 213950.0 260904.0 186131.0 True False 241326.85042587755 235201.14230575223 266617.1291462885 253109.3123056633 235704.90567415406 251197.86556322925 235432.49526778952 223890.8980628746 231518.2440790805 218303.49534603197 1.1054648943817933 1.0774043811480705 1.2213140642740272 1.1594377447070225 1.079712009652155 1.1506818301972515 1.0784641578670393 1.0255946553122572 1.0605338394243384 1.0 17.735975704527384 -7.509744790564277 3.0232020251987355 1.0322243546770489 1.1327387052791098 0.5523004292378457 0.04186942843174759 0.21593757988626944 4.018451160300571 0.022275677065050067 0.012720244647683225 3.092111951857398e-08 7.509744790564277 0.10051435060206093 SSRDPPSSPS(ph)SLSSPIQESTAPELPSETQETPGPALCSPLRK ddPTM_PC-9_Lapatinib_30min_R1 1 SSRDPPSSPSSLSSPIQESTAPELPSETQETPGPALCSPLRK 42 2 Q16512;Q16512-2 Q16512 PKN1 Serine/threonine-protein kinase N1 1 S(0.003)S(0.003)RDPPS(0.013)S(0.032)PS(0.236)S(0.236)LS(0.236)S(0.236)PIQES(0.002)T(0.001)APELPSETQETPGPALCSPLRK 49.699 0.00043056 5417300.0 19368.0 8934.5 9352.4 6653.9 9114.3 9530.7 6158.4 6643.1 15605.0 8773.2 True False 19091.808768343806 8913.81271418404 8583.481773308005 7143.25000275971 8578.214793403245 9123.094178146823 6477.251818717374 6951.762677828868 13847.400572065018 10289.635930445813 1.8554406489595425 0.8662903891292328 0.834187121034137 0.6942179539728592 0.8336752487054789 0.8866294434337243 0.6294928083463044 0.6756082260655526 1.3457619555899156 1.0 13.328904317016283 -4.76134573066035 6.4357113240479595 0.837214520504224 1.8851756195439353 0.7002934293276297 0.19424120650951193 0.06428915692079398 12.2136339378536 0.04690303187690932 0.29568021523594495 1.732424310251188e-05 4.76134573066035 1.0479610990397115 SSRS(ph)DSNFQVPNGGIPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSRSDSNFQVPNGGIPR 17 1 Q9P270;D6RIF6;H0Y9L2 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 S(0.193)S(0.03)RS(0.669)DS(0.108)NFQVPNGGIPR 138.28 3.2129000000000004e-05 4725900.0 17887.0 14534.0 9552.8 15874.0 17056.0 12243.0 12343.0 13898.0 13844.0 10911.0 True False 17631.928099925924 14500.34741596629 8767.405658874372 17041.426914111657 16052.79961338619 11719.395429826936 12982.060145237172 14543.751817143428 12284.742936217117 12796.95181200638 1.377822497024898 1.1331094802093218 0.685116720580959 1.3316786031907237 1.2544236978625725 0.9157958552935663 1.0144650332321419 1.1365012567678938 0.9599741498355336 1.0 13.643512585914767 -6.7662479065745895 24.997590021905168 1.0144484672857639 1.1386865408171905 0.1389192012641588 0.18476720665487362 328.1127547603628 1705713.8485432693 0.06712721410616683 0.06107977800116618 1.71297921533014e-07 6.7662479065745895 0.12423807353142657 SSRS(ph)SPELTR ddPTM_PC-9_AZD4547_30min_R2 1 SSRSSPELTR 10 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.045)S(0.045)RS(0.875)S(0.033)PELTR 60.08 0.032917 28438000.0 7774.8 3073.8 11471.0 16085.0 10224.0 8197.5 6675.4 10985.0 8000.4 10708.0 True False 10247.024674113829 4067.345738564863 11318.887044981744 12376.851760772714 8804.57407908615 7684.909029114792 7269.497668036675 9287.520660187767 8423.284810859688 10333.116179261531 0.991668388929906 0.3936223756709509 1.09539918535888 1.1977850191613002 0.8520734622878671 0.7437165029208066 0.7035145586213857 0.8988112103905049 0.8151737254019406 1.0 13.334987775902542 -6.514418299678025 24.595331574678685 0.815653523034851 0.9108940368279497 0.03359133912518486 0.2119179534500716 1356.4953063915577 3943476.8631880125 0.07187371431857642 0.07535274434029907 3.05901566035601e-07 6.514418299678025 0.09524051379309872 SSS(ph)ADSLSTTK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSADSLSTTK 11 0 Q9UQ84;Q9UQ84-4;H0YAZ2 Q9UQ84 EXO1 Exonuclease 1 1 S(0.002)S(0.044)S(0.867)ADS(0.078)LS(0.004)T(0.004)TK 74.392 0.022887 4765800.0 66670.0 42874.0 53078.0 42773.0 54614.0 43582.0 39901.0 43859.0 58653.0 38496.0 True False 65719.27357421933 42774.72788717069 48714.13172700508 45918.669106545196 51401.71189525524 41718.09945460408 41966.87854290759 45896.84925515137 52046.88149652865 45149.98230730429 1.4555769507707508 0.947391908063952 1.0789402174167448 1.0170251849493315 1.1384658258645552 0.923989275802108 0.9294993352880728 1.0165419100889936 1.1527553021456796 1.0 15.462437801914069 -4.755357263436711 24.99937947379695 1.022446511322575 1.4555776595081737 0.7435140934561469 0.07626712930390757 102.78141868426388 422422.40763285744 0.019211974256514396 0.17173136476642026 1.75647808884631e-05 4.755357263436711 0.43313114818559884 SSS(ph)APLIHGLSDLSQVFQPYTLR ddPTM_PC-9_AZD4547_30min_R2 2 SSSAPLIHGLSDLSQVFQPYTLR 23 0 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 S(0.043)S(0.043)S(0.914)APLIHGLSDLSQVFQPYTLR;S(0.145)S(0.145)S(0.709)APLIHGLSDLSQVFQPYTLR 153.34 1.3046e-08 155176000.0 25739.1 25451.9 51451.2 60257.9 57725.2 42574.7 31319.2 56507.3 38669.1 45348.5 True False 33923.59839346131 33678.728935968225 50768.92347038312 46366.37213027456 49711.05238948194 39912.49727866466 34106.54812667019 47775.39519357557 40713.06968146772 43760.86281800912 0.775204056979895 0.7696084301634989 1.1601444807319918 1.0595397152725514 1.135970572523175 0.9120591941857069 0.7793847271364622 1.0917379621206722 0.9303534496288057 1.0 15.417353563086486 -5.2337592980119405 23.967318627346717 1.0066522263624813 0.7724060530414635 0.4331893341710351 0.10807384343967927 437.9769672888526 379227.75935125863 0.029195135381844095 0.07719242464455708 5.8376856065432705e-06 5.2337592980119405 -0.23424617332101783 SSS(ph)APLIHGLSDLSQVFQPYTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSAPLIHGLSDLSQVFQPYTLR 23 0 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 S(0.185)S(0.185)S(0.629)APLIHGLSDLSQVFQPYTLR;S(0.165)S(0.165)S(0.669)APLIHGLSDLSQVFQPYTLR 130.52 4.6728000000000004e-07 91496000.0 118283.0 124675.0 228479.0 254620.0 256904.0 273006.0 246680.0 211257.0 227445.0 185649.0 True False 138305.97570426037 137051.91005162944 233926.80587143268 240354.4668891775 206565.50540079444 258689.08476040413 223312.68459145853 205711.72759529357 230770.95284133466 219305.69410332467 0.6306538289840221 0.6249354838322537 1.0666700052084346 1.0959791439611952 0.9419067126614243 1.179582161868192 1.018271256040648 0.93801361809773 1.052279804155966 1.0 17.742583745399443 -5.259210088572419 24.988407013923126 1.0375664701536225 0.6277946094965474 0.8545578947189665 0.06745773216935814 62.77721364980595 703666.0175103511 0.01741148389518946 0.04168321781024766 5.505413093736902e-06 5.259210088572419 -0.40977186065707505 SSS(ph)APLIHGLSDLSQVFQPYTLR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSAPLIHGLSDLSQVFQPYTLR 23 0 G1UD79;Q7Z309-3;Q7Z309-4;Q7Z309-2;Q7Z309 G1UD79;Q7Z309-2 SPACIA2;FAM122B Protein FAM122B 1 S(0.175)S(0.175)S(0.65)APLIHGLSDLSQVFQPYTLR;S(0.14)S(0.14)S(0.72)APLIHGLSDLSQVFQPYTLR 69.952 0.00061054 22650000.0 16553.3 5938.07 14594.2 15249.8 11745.22 17680.92 14900.19 9898.6 17861.9 11631.5 True False 16317.24690649656 5924.320763748934 13394.321211241146 16371.321163841505 11054.389251590976 16924.74826783759 15671.648931010393 10358.525092615917 15850.104727854423 13641.989277000475 1.196104657112317 0.434271032138763 0.9818451649000427 1.2000684673929856 0.8103209163364445 1.2406363855139246 1.1487803290852745 0.7593119216183325 1.161861690844215 1.0 13.735766413266907 -5.502621071149832 24.87737134840568 1.0424578023689648 0.7884053944837184 0.13598716204934302 0.22741355825684678 1160.2114188268579 1424791.4237132329 0.056047004061009015 0.11434629578015722 3.1432500334711773e-06 5.502621071149832 -0.2540524078852464 SSS(ph)APNVHINTIEPVNIDDLIR ddPTM_PC-9_AZD4547_30min_R2 5 SSSAPNVHINTIEPVNIDDLIR 22 0 H7C560;P15056;A0A2R8Y679;A0A2R8Y492;A0A2R8YDP5;A0A2R8Y8E0;A0A2U3TZI2 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 S(0.131)S(0.131)S(0.738)APNVHINTIEPVNIDDLIR;S(0.139)S(0.139)S(0.723)APNVHINTIEPVNIDDLIR;S(0.191)S(0.191)S(0.619)APNVHINTIEPVNIDDLIR;S(0.046)S(0.046)S(0.908)APNVHINTIEPVNIDDLIR;S(0.149)S(0.149)S(0.703)APNVHINTIEPVNIDDLIR 149.07 7.5463e-07 167647300.0 47306.0 46795.4 71091.5 95047.7 80633.5 64687.1 56817.0 83381.1 62539.2 70156.0 True False 62348.323974073726 61921.097916077284 70148.78025963908 73135.92123732647 69438.93036052345 60642.20541107063 61873.602930886525 70496.4669020647 65844.89443569271 67699.85979382436 0.9209520398410218 0.9146414498442695 1.036173198486271 1.080296494853273 1.0256879493103135 0.8957508271915574 0.9139398976499902 1.041308905465347 0.9726001595308936 1.0 16.046865225536372 SSS(ph)APNVHINTIEPVNIDDLIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSSAPNVHINTIEPVNIDDLIR 22 0 H7C560;P15056;A0A2R8Y679;A0A2R8Y492;A0A2R8YDP5;A0A2R8Y8E0;A0A2U3TZI2 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 S(0.035)S(0.035)S(0.931)APNVHINTIEPVNIDDLIR;S(0.13)S(0.13)S(0.74)APNVHINTIEPVNIDDLIR;S(0.125)S(0.125)S(0.749)APNVHINTIEPVNIDDLIR;S(0.15)S(0.15)S(0.7)APNVHINTIEPVNIDDLIR 161.55 6.721800000000001e-07 127759000.0 66201.0 82777.0 88706.0 93667.0 101477.0 82541.0 74101.0 73406.0 72952.0 57469.4 True False 77407.52177064978 90994.55350586526 90821.08745937856 88419.14166251123 81593.31030873959 78212.404654874 67081.61683521839 71479.17028008598 74018.7849883755 67888.1472924799 1.1402214503977832 1.3403599469851035 1.3378047727256062 1.3024238425829833 1.2018785835650259 1.1520774652740853 0.9881197161886482 1.052896170109563 1.0903049787098062 1.0 16.05087209341535 -6.818820401555198 1.8439694105764646 1.0376039693881687 1.2863082978769464 0.7606122531472725 0.06152092173159512 0.1637965995779938 1.1478000837272706 0.02616668954641341 0.02295901740757986 1.5176778592706102e-07 6.818820401555198 0.24870432848877777 SSS(ph)APNVHINTIEPVNIDDLIR ddPTM_PC-9_Lapatinib_30min_R1 5 SSSAPNVHINTIEPVNIDDLIR 22 0 H7C560;P15056;A0A2R8Y679;A0A2R8Y492;A0A2R8YDP5;A0A2R8Y8E0;A0A2U3TZI2 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 S(0.047)S(0.047)S(0.906)APNVHINTIEPVNIDDLIR;S(0.039)S(0.039)S(0.921)APNVHINTIEPVNIDDLIR;S(0.167)S(0.167)S(0.665)APNVHINTIEPVNIDDLIR;S(0.038)S(0.038)S(0.924)APNVHINTIEPVNIDDLIR;S(0.124)S(0.124)S(0.752)APNVHINTIEPVNIDDLIR 136.61 6.8262e-07 138924710.0 87049.0 85454.0 106301.4 82468.3 87075.8 72906.2 67608.0 73426.0 87515.2 64563.0 True False 85807.6652971684 85256.1365132779 97561.70922727023 88533.29388818413 81954.17264160966 69788.17177865304 71108.41143151544 76837.64001479157 77658.31660008867 75722.62852521015 1.1331839235955823 1.1259003837260322 1.2884089092970306 1.1691788255700732 1.0822943450031566 0.921629018139784 0.9390642244787037 1.014724944330349 1.0255628748311882 1.0 16.208436871077954 -6.47967806237612 3.2435656908339867 0.9790518829386381 1.1822159331824809 0.7670904108102072 0.05150464874700593 0.1257544185460699 2.665835841932419 0.018561123428797465 0.02031043245063731 3.3137667626780054e-07 6.47967806237612 0.20316405024384276 SSS(ph)ASSPEMK ddPTM_PC-9_AZD4547_30min_R2 7 SSSASSPEMK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.001)S(0.021)S(0.962)AS(0.007)S(0.009)PEMK;SS(0.01)S(0.987)AS(0.002)S(0.001)PEMK;SS(0.017)S(0.983)AS(0.001)SPEMK;S(0.001)S(0.009)S(0.971)AS(0.019)SPEMK;SS(0.005)S(0.982)AS(0.013)SPEMK;SS(0.028)S(0.916)AS(0.043)S(0.012)PEMK;S(0.005)S(0.188)S(0.725)AS(0.081)S(0.002)PEMK 128.88 0.00026489 220530800.0 657032.0 615756.0 781252.0 945670.0 818938.0 754250.0 741252.0 785813.0 699313.0 718162.0 True False 865954.5088854177 814787.0852351311 770892.0880190105 727660.3919558552 705242.5945988516 707086.6282659153 807221.9920046034 664383.6570363323 736277.2575042153 693019.3669714995 1.249538685577643 1.1757060827834545 1.1123673085613976 1.0499856521120574 1.0176376421928404 1.020298511073204 1.1647899474038803 0.9586797840004018 1.0624194540504015 1.0 19.402536144610735 -5.176116195348807 1.28446873742469 1.0391603066412958 1.2714215088463763 0.6615599389829471 0.05068587871185262 0.46016531955766915 1.0544684810576213 0.015579718912511321 0.11695799673968124 6.666283891410351e-06 5.176116195348807 0.2322612022050805 SSS(ph)ASSPEMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SSSASSPEMK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.002)S(0.025)S(0.961)AS(0.011)SPEMK;SS(0.004)S(0.994)AS(0.002)SPEMK;S(0.001)S(0.059)S(0.912)AS(0.028)S(0.001)PEMK;SS(0.03)S(0.844)AS(0.072)S(0.054)PEMK;S(0.019)S(0.059)S(0.805)AS(0.112)S(0.005)PEMK;S(0.002)S(0.004)S(0.935)AS(0.059)SPEMK 99.34299999999999 0.0038835999999999996 251725000.0 459244.0 494917.0 502519.0 612427.0 725554.0 675809.0 775722.0 745817.0 701951.0 601428.0 True False 536984.9387175443 544049.0889674935 514500.95877391956 578114.7007051223 583386.90213297 640368.3863462495 702239.9964190678 726240.0940084306 712215.7054141762 710462.1354985727 0.7558248524261052 0.7657678879476139 0.7241778739029692 0.8137164133306352 0.8211372189787052 0.9013406265442502 0.9884270551959325 1.0222080216826552 1.0024682102366693 1.0 19.43839823666476 -6.854161554020516 1.145197125211437 1.0165483074414652 0.7541802542654654 0.969720950877153 0.019254391117335328 0.07251925075157924 0.19990329355713815 0.01056551796580264 0.008715627254771314 1.3990667842781867e-07 6.854161554020516 -0.26236805317599976 SSS(ph)ASSPEMK ddPTM_PC-9_Lapatinib_30min_R1 6 SSSASSPEMK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.001)S(0.044)S(0.917)AS(0.019)S(0.019)PEMK;S(0.001)S(0.051)S(0.932)AS(0.016)S(0.001)PEMK;S(0.001)S(0.002)S(0.996)AS(0.002)SPEMK;S(0.002)S(0.035)S(0.946)AS(0.016)SPEMK;S(0.019)S(0.003)S(0.488)AS(0.488)S(0.002)PEMK;S(0.001)S(0.03)S(0.968)AS(0.001)SPEMK 156.01 9.545600000000001e-13 107303400.0 688373.0 645463.0 629465.0 597557.0 718493.0 782289.0 757397.0 726868.0 853017.0 684729.0 True False 678556.6747878537 643968.4700806274 577712.8175051677 641503.3351717171 676232.654351588 748832.323074728 796611.3106880169 760640.9408420927 756941.2427927713 803083.4953059601 0.8449391361596046 0.8018698850675385 0.7193683108691826 0.7988002977539914 0.8420452646632413 0.9324464111784998 0.9919408322350376 0.9471505083693726 0.9425436423698268 1.0 19.61519046467218 -6.690015480655051 2.1857329421460197 0.9666311548829052 0.7874039648519779 0.8598076829414296 0.03332736076230362 0.11387850287643216 1.1156380670355959 0.01343689138664643 0.012972325884987168 2.0416651671445614e-07 6.690015480655051 -0.17922719003092724 SSS(ph)DS(ph)SYMSGSPGGSPGS(ph)GS(ph)AEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSDSSYMSGSPGGSPGSGSAEK 23 0 H0YLL1;Q14005-2;Q14005 H0YLL1 IL16 Pro-interleukin-16;Interleukin-16 4 S(0.302)S(0.329)S(0.359)DS(0.339)S(0.336)Y(0.308)MS(0.017)GS(0.017)PGGS(0.03)PGS(0.982)GS(0.98)AEK 52.268 0.030379000000000003 0.0 11954.0 11925.0 14417.0 13129.0 18108.0 13884.0 17594.0 17112.0 16154.0 8556.5 True False 13977.57609773787 13108.83519042056 14760.75595677697 12393.424694792298 14559.867389365641 13155.898598614871 15927.368950470749 16662.828131662707 16390.221689634483 10107.725716783267 1.3828606443612683 1.2969124368555165 1.4603439359526376 1.2261338546428666 1.4404691814291977 1.301568618623109 1.5757618871695656 1.6485239705302934 1.6215538637360838 1.0 13.30317080050735 -7.259389534735099 24.971327670589062 1.5155035961586298 1.3522147906521134 0.048635245116508075 0.18446024358551788 338.5828788357745 4124670.538521095 0.06824764386501064 0.05027297333184367 5.503138781668803e-08 7.259389534735099 -0.16328880550651648 SSS(ph)EDAESLAPR ddPTM_PC-9_AZD4547_30min_R2 1 SSSEDAESLAPR 12 0 H0YA82;Q4G0J3;Q4G0J3-3 H0YA82 LARP7 La-related protein 7 1 S(0.15)S(0.025)S(0.824)EDAESLAPR 171.62 0.0011136 189330000.0 63503.0 63859.0 83850.0 133200.0 103570.0 101030.0 74818.0 117870.0 82494.0 97785.0 True False 83695.63305554495 84500.17291919242 82738.09421338333 102492.79791948567 89191.0932483325 94712.578128877 81476.65705832881 99655.89988314333 86854.46442516119 94361.5769134376 0.8869672995431496 0.8954934379351087 0.8768197493062557 1.0861708893812492 0.9452056246384243 1.0037197472416277 0.8634516264291688 1.05610676657685 0.9204431217256676 1.0 16.525911907772723 SSS(ph)EDAESLAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSEDAESLAPR 12 0 H0YA82;Q4G0J3;Q4G0J3-3 H0YA82 LARP7 La-related protein 7 1 S(0.347)S(0.06)S(0.593)EDAESLAPR 153.49 0.00021840000000000002 96295000.0 42021.0 58966.0 85030.0 32862.0 70859.0 116650.0 125900.0 96522.0 86998.0 77718.0 True False 49134.32534741869 64819.75478728209 87057.43767807091 31020.848680041487 56974.687615587616 110532.66864941121 113973.8405629342 93988.39977351254 88270.18116595404 91807.65818465032 0.5351876555722195 0.706038647199908 0.9482589949410819 0.33788955402445914 0.6205875276874607 1.2039591340746298 1.2414415400260141 1.0237533734329238 0.9614686063380307 1.0 16.486326881382425 -6.754434695965923 24.99859479626394 1.0973164416885253 0.6353373808058145 0.6607469893314477 0.16343891572118424 105.08041753823666 375014.8244201921 0.05707391951328662 0.05590141629052498 1.7602133238277228e-07 6.754434695965923 -0.4619790608827108 SSS(ph)EITLSECDAEDAGEPR ddPTM_PC-9_AZD4547_30min_R2 3 SSSEITLSECDAEDAGEPR 19 0 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 S(0.307)S(0.044)S(0.649)EITLSECDAEDAGEPR;S(0.009)S(0.009)S(0.983)EITLSECDAEDAGEPR;SSS(0.999)EITLSECDAEDAGEPR 384.32 0.0 87025000.0 26771.6 28616.300000000003 43250.5 47449.9 44012.5 38363.5 36203.7 45678.4 36618.8 35321.1 True False 35284.411916127174 37865.95935275349 42676.97011062533 36511.05864864712 37902.12408605035 35964.624280383716 39425.759164139876 38619.85286520897 38554.39500923812 34084.519039906125 1.0352034562909986 1.110943044507099 1.2520924840001166 1.07119183949464 1.1120040755650558 1.0551600930110343 1.1567057501377747 1.1330614001034571 1.1311409430216302 1.0 15.056829005143953 -10.675409479768266 4.902725257678676 0.9999916337955983 1.1195196454476954 0.2729889455314872 0.05744021938219864 5.284615488678937e-06 9.134878830577284e-07 0.05595445632774935 0.013569999118542701 2.1114972504506444e-11 10.675409479768266 0.11952801165209714 SSS(ph)EITLSECDAEDAGEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSSEITLSECDAEDAGEPR 19 0 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 S(0.004)S(0.004)S(0.99)EIT(0.002)LSECDAEDAGEPR;SS(0.011)S(0.989)EITLSECDAEDAGEPR;SS(0.001)S(0.999)EITLSECDAEDAGEPR 362.02 2.0081999999999987e-275 76990400.0 77271.2 69291.3 90692.6 85348.6 108648.4 87114.8 104846.3 94343.3 85118.5 70474.1 True False 90351.687984233 76170.08233375159 92855.0555376007 80566.79464589446 87359.5259590652 82546.34653115933 94914.49944252228 91866.88833998928 86363.19703411864 83250.49645733122 1.0852990892437666 0.9149504876861775 1.1153693910425164 0.9677635338449634 1.049357417391979 0.9915417930686721 1.1401073084431308 1.1034995855799403 1.0373895737472603 1.0 16.345171255149495 -7.2392669337228455 24.981788295394516 1.0788740959990093 1.019103907839922 0.11944615021563942 0.06411362800719284 1375.4770678786672 1549758.5142603356 0.02290637373237812 0.017725010454306175 5.7641206995398754e-08 7.2392669337228455 -0.0597701881590873 SSS(ph)EITLSECDAEDAGEPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSEITLSECDAEDAGEPR 19 0 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 S(0.014)S(0.002)S(0.984)EITLSECDAEDAGEPR 181.86 2.161e-09 2745000.0 4328.4 3113.6 6102.6 6915.1 5620.2 4437.7 3931.1 4854.4 5673.6 3028.3 True False 4266.676222268656 3106.3906504990127 5600.867784717233 7423.659522097368 5289.6308857383365 4247.909915783956 4134.6331229799725 5079.953145858475 5034.579422343356 3551.737620043894 1.2012926287657268 0.8746115233761617 1.5769373709108656 2.090148630406326 1.4893078970380038 1.196008931462527 1.1641155865924788 1.4302726409716309 1.4174975634267535 1.0 11.79430929308349 -10.59640973152842 4.214130624645009 0.9999592119973921 1.386528849939707 0.12410556730505018 0.30445190413800627 239643871.68814534 480085523.2678892 160716.8541684771 0.08424954241521605 2.5327380122908125e-11 10.59640973152842 0.3865696379423149 SSS(ph)ENDVELLTK ddPTM_PC-9_AZD4547_30min_R2 3 SSSENDVELLTK 12 0 Q9C0D6 Q9C0D6 FHDC1 FH2 domain-containing protein 1 1 S(0.001)S(0.033)S(0.966)ENDVELLTK;S(0.174)S(0.174)S(0.652)ENDVELLTK;S(0.016)S(0.027)S(0.957)ENDVELLTK 207.08 6.382000000000001e-08 28726200.0 114233.0 119759.0 174646.0 222070.0 222455.0 184615.0 180023.0 216652.0 179460.0 187729.0 True False 150556.71780599433 158468.75473511274 172330.07992833084 170875.1924472984 191570.96310280784 173070.99486551093 196044.6982492388 183173.41156768307 188945.8892251488 181156.66485026025 0.8310857231250139 0.8747608312733026 0.9512765101453747 0.9432454090968154 1.0574878007450392 0.955366422806289 1.082183194370931 1.011132611207486 1.0429971725375213 1.0 17.466878358723953 -5.191063585480258 0.7337603972132476 1.0303535679818776 0.767759823926067 0.7783874455807975 0.03571633800746402 0.7595351048919609 0.4538629512185829 0.014792424793591486 0.1500292907699464 6.440749589663147e-06 5.191063585480258 -0.2625937440558106 SSS(ph)ENDVELLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSSENDVELLTK 12 0 Q9C0D6 Q9C0D6 FHDC1 FH2 domain-containing protein 1 1 S(0.113)S(0.113)S(0.774)ENDVELLTK;S(0.022)S(0.022)S(0.955)ENDVELLTK;SS(0.021)S(0.979)ENDVELLTK 236.12 1.1627e-21 23219400.0 92926.0 115094.0 131407.0 156337.0 170917.0 154292.0 159167.0 131594.0 134541.0 121238.0 True False 108656.536427839 126519.77169025267 134540.24124382244 147577.94474139242 137427.04078795025 146200.65590445747 144089.54949071104 128139.7969353685 136508.40759843454 143217.48968051985 0.7586820343676101 0.8834100637602618 0.9394120895705264 1.0304463866152074 0.9595688424263925 1.0208296223498419 1.0060890594587053 0.8947217076714187 0.9531545895892221 1.0 17.127848159319782 -4.8464691623999885 1.6083172448139818 0.9779140620738552 0.6972167400989381 0.7624963923605578 0.03811022903274794 0.4499723166407076 1.2500665726125506 0.011449378718889177 0.19238206934791108 1.4240683607364534e-05 4.8464691623999885 -0.28069732197491715 SSS(ph)ENDVELLTK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSENDVELLTK 12 0 Q9C0D6 Q9C0D6 FHDC1 FH2 domain-containing protein 1 1 SS(0.078)S(0.922)ENDVELLTK;S(0.037)S(0.127)S(0.835)ENDVELLTK 217.39 6.5197e-11 28973000.0 175877.0 169717.0 176148.0 153716.0 152974.0 129664.0 146706.0 126395.0 165310.0 131911.0 True False 173368.961728108 169324.03071388105 161665.79139094343 165020.78742154394 143976.37007845557 124118.57298154692 154301.71884202905 132267.77312763303 146691.04700852718 154711.640589641 1.120594165166627 1.094449196379464 1.0449491116169318 1.0666345906010204 0.9306111003007215 0.8022574934148653 0.9973504143188603 0.8549309710861489 0.9481577885765704 1.0 17.23922222448261 -6.260681477055485 4.058034450320867 0.9112583755751039 1.082371586486264 0.6363596359511103 0.058966862163388784 0.13072242298986078 5.178441632962662 0.017669864656506475 0.021719650880929794 5.486792331018868e-07 6.260681477055485 0.17111321091116005 SSS(ph)ENDVELLTKK ddPTM_PC-9_AZD4547_30min_R2 1 SSSENDVELLTKK 13 1 Q9C0D6 Q9C0D6 FHDC1 FH2 domain-containing protein 1 1 S(0.171)S(0.171)S(0.659)ENDVELLTKK 63.292 0.021106 4421800.0 12866.0 10970.0 19897.0 29549.0 23172.0 20665.0 19784.0 20615.0 16062.0 23466.0 True False 16957.120370575252 14515.837969957889 19633.152779531152 22736.934577499083 19954.967777834914 19372.814283215266 21544.737673313586 17429.42543557312 16911.00452877711 22644.46248249452 0.748841814358989 0.6410325694937326 0.8670178324925449 1.0040836515804272 0.8812294746789092 0.8555210483883895 0.9514351550613717 0.7696992343733959 0.7468052969616874 1.0 14.466870673715867 -5.304243123144126 8.270921277055722 0.8820042696426674 0.6951075512734624 0.4463321670918362 0.08441588315200234 0.27275190863798054 49.65944383492286 0.022769425764049556 0.04802698064363984 4.963144010438483e-06 5.304243123144126 -0.18689671836920507 SSS(ph)EPAVHAPGTPGNPVSLSTNSSLASSGELVEPR ddPTM_PC-9_AZD4547_30min_R2 1 SSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPR 35 0 H0Y6J8;Q8N3F8 H0Y6J8;Q8N3F8 MICALL1 MICAL-like protein 1 1 S(0.161)S(0.161)S(0.613)EPAVHAPGT(0.063)PGNPVS(0.001)LSTNSSLASSGELVEPR 74.377 2.4841e-08 3981700.0 4861.5 4201.4 6313.5 12338.0 8823.0 7810.6 8563.0 6388.6 5527.6 7739.3 True False 6407.3558745182345 5559.420387145041 6229.77886483238 9493.6647201998 7598.078746065832 7322.201947277097 9325.09041127094 5401.388665423351 5819.7776511809425 7468.349462659579 0.8579346623445884 0.7443974622426488 0.8341573859097204 1.271186460631822 1.0173705427223079 0.9804310823812954 1.248614631371327 0.7232372684793789 0.7792588818023041 1.0 12.866573721097403 -5.549970862060171 24.99697135457767 1.0052036540460996 0.7981936018221132 0.2234190615383329 0.16364707465396597 310.0909538655283 286108.94119897083 0.04669675099587236 0.08088355954562917 2.818572030206841e-06 5.549970862060171 -0.20701005222398638 SSS(ph)EPAVHAPGTPGNPVSLSTNSSLASSGELVEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPR 35 0 H0Y6J8;Q8N3F8 H0Y6J8;Q8N3F8 MICALL1 MICAL-like protein 1 1 S(0.131)S(0.131)S(0.737)EPAVHAPGTPGNPVSLSTNSSLASSGELVEPR;S(0.19)S(0.19)S(0.584)EPAVHAPGT(0.031)PGNPVS(0.006)LSTNSSLASSGELVEPR 124.66 4.369600000000001e-15 10294000.0 17547.1 22723.8 25017.0 25417.3 30720.4 25090.4 23630.7 19401.9 19034.0 15791.4 True False 20517.477458977446 24979.668687637633 25613.500157500843 23993.251084998436 24700.9581482366 23774.61525487515 21392.2290245475 18892.6206830123 19312.336241209796 18654.255815346383 1.0998818533462074 1.339086851542343 1.3730646996075428 1.286207893925192 1.324145996106462 1.2744874676435163 1.146774721881355 1.012778042181121 1.0352777635504509 1.0 14.187217186612505 -7.4862888763173165 2.1928715641612544 1.0138535817713092 1.2936315416395727 0.7489475664353087 0.06934779004999365 0.15592774681245505 1.48025031042981 0.03924466438209289 0.02124532850707573 3.2637067048998104e-08 7.4862888763173165 0.2797779598682635 SSS(ph)EPAVHAPGTPGNPVSLSTNSSLASSGELVEPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPR 35 0 H0Y6J8;Q8N3F8 H0Y6J8;Q8N3F8 MICALL1 MICAL-like protein 1 1 S(0.059)S(0.059)S(0.851)EPAVHAPGT(0.032)PGNPVSLSTNSSLASSGELVEPR 125.37 4.727399999999999e-23 10752000.0 12232.0 8117.2 13769.0 8785.7 14161.0 7811.6 7480.5 7761.2 9273.2 7265.6 True False 12057.569436925927 8098.405122119286 12636.965969877027 9431.829686236038 13328.077821597199 7477.516077728995 7867.803687632388 8121.813685653593 8228.754564874938 8521.449279196544 1.4149669899886783 0.9503553746297548 1.482959712114665 1.106833987648323 1.5640623308214836 0.8774934676879309 0.9232940817755139 0.9531023913363442 0.9656520029948236 1.0 13.056883101274964 -6.787577805985049 24.9999193383646 0.9396887667680515 1.2832047938473796 0.5287540010571017 0.1693128504439534 178.8541248280153 171062.4974417992 0.055870753483475914 0.049288681692714574 1.63088070278214e-07 6.787577805985049 0.34351602707932816 SSS(ph)ES(ph)LIFSGNQGRGHQRPLPPS(ph)EGLSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSESLIFSGNQGRGHQRPLPPSEGLSPR 29 2 Q8IZW8 Q8IZW8 TNS4 Tensin-4 3 S(0.207)S(0.207)S(0.666)ES(0.666)LIFS(0.257)GNQGRGHQRPLPPS(0.794)EGLS(0.205)PR 40.285 0.045541000000000005 0.0 10758.0 11066.0 10956.0 12105.0 12243.0 12016.0 12240.0 11558.0 8898.0 8646.6 True False 12579.116919814634 12164.55934735379 11217.232590861377 11426.796094939507 9844.072037110871 11385.859807040939 11080.538590073998 11254.614746713278 9028.116416637842 10214.160133552059 1.2315370774826635 1.1909505224413848 1.098204105300285 1.1187210642414067 0.9637671534808328 1.1147132665014732 1.0848213113162393 1.1018639417785778 0.8838824042890974 1.0 13.318282961890453 -1.5228787452803614 0.29525488280128415 1.0023894428037639 3.001537782562052 0.5566895009526298 0.06563246395926202 42.72887107705359 0.6078696320221588 0.0687473367109341 44.87094642818443 0.029999999999998354 1.5228787452803614 1.999148339758288 SSS(ph)ESKLPSSGSGK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSESKLPSSGSGK 14 1 P57078-2;P57078 P57078-2 RIPK4 Receptor-interacting serine/threonine-protein kinase 4 1 S(0.12)S(0.368)S(0.509)ES(0.003)KLPSSGSGK 95.755 0.022728 0.0 6291.8 6098.9 7100.2 6698.5 7579.2 7284.5 5038.8 7277.0 6674.6 5758.5 True False 6202.07777822519 6084.778371765296 6516.448963564591 7191.130035540942 7133.406357280517 6972.958915998882 5299.68440896225 7615.115985994586 5922.836261346053 6753.849052281064 0.9183026937995427 0.9009349075858017 0.9648496602635362 1.0647454480955847 1.056198665688458 1.0324422210241455 0.7846909766472082 1.1275223842058826 0.8769571566521253 1.0 12.721494220306099 -5.413916385920485 4.549965258214365 0.9942180721035975 0.9109718677107551 0.1078093407428774 0.09274668438658776 0.4830753112985637 15.961781019021062 0.024168004656471724 0.05231924929466637 3.855525803932648e-06 5.413916385920485 -0.08324620439284236 SSS(ph)ESYTQSFQSR ddPTM_PC-9_AZD4547_30min_R2 2 SSSESYTQSFQSR 13 0 Q9BTU6;E9PAM4 Q9BTU6 PI4K2A Phosphatidylinositol 4-kinase type 2-alpha 1 SSS(1)ESYTQSFQSR;S(0.006)S(0.066)S(0.927)ES(0.001)YTQSFQSR 193.11 1.4894999999999999e-06 38650000.0 46089.0 55972.0 74425.0 90338.0 69348.0 53428.0 63934.0 76120.0 56969.0 61416.0 True False 60744.34328924625 74063.85440788357 73438.07587156881 69511.96980818683 59720.227233613594 50087.1387139427 69624.0021434307 64357.403063585996 59980.2650354814 59265.84453357553 1.0249468942407987 1.2496886695999854 1.2391298301665872 1.172884151997642 1.0076668560722297 0.8451265498387883 1.1747744875884967 1.085910503260035 1.0120545063945074 1.0 15.854913285022368 -6.248422697540968 11.043687461759207 1.0241129698758151 1.1821029561475205 0.36963528167779924 0.09599681181628654 0.6197450128700552 517.3229360782502 0.029677269086629772 0.037270610961507446 5.643873908151382e-07 6.248422697540968 0.15798998627170535 SSS(ph)ESYTQSFQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSESYTQSFQSR 13 0 Q9BTU6;E9PAM4 Q9BTU6 PI4K2A Phosphatidylinositol 4-kinase type 2-alpha 1 S(0.015)S(0.002)S(0.983)ESYTQSFQSR 194.77 1.2392e-06 14392000.0 16502.0 17851.0 14383.0 17318.0 26815.0 19608.0 21628.0 20750.0 20068.0 18015.0 True False 19295.46267064333 19623.129306850944 14725.94526783126 16347.728605713542 21560.79324308813 18579.721962088766 19579.23926683989 20205.33448644233 20361.45653507397 21280.976893338466 0.9067000432993911 0.9220972047102558 0.6919769398575348 0.7681850644192388 1.0131486609450366 0.8730671554793489 0.9200347975082259 0.9494552147541291 0.9567914404083427 1.0 14.37727675815295 -6.256567739297422 24.997789326253535 0.9440024490250997 0.8200679925697462 0.4411821951749245 0.07122549865044657 444.85085014761995 2282657.558970161 0.022732609201625904 0.028390873567535266 5.539011421948518e-07 6.256567739297422 -0.1239344564553535 SSS(ph)ETILSSLAGSDIVK ddPTM_PC-9_AZD4547_30min_R2 3 SSSETILSSLAGSDIVK 17 0 Q01850 Q01850 CDR2 Cerebellar degeneration-related protein 2 1 S(0.026)S(0.026)S(0.946)ET(0.001)ILSSLAGSDIVK;SS(0.006)S(0.992)ET(0.002)ILSSLAGSDIVK;S(0.179)S(0.179)S(0.642)ETILSSLAGSDIVK 380.5 1.0372999999999992e-295 65171000.0 172517.0 144016.0 212837.0 290441.0 246477.0 218236.0 221039.0 273371.0 207659.0 244481.0 True False 227373.81742348277 190566.35561362386 210014.6423147745 223484.31471871876 212257.92305271118 204589.66842060324 240711.04279071753 231127.79339064032 218635.43079574927 235921.79460422456 0.96376775110972 0.8077522296458975 0.8901875414566461 0.9472813441997991 0.8996961192533687 0.8671927439506674 1.0203001515588133 0.9796797018197216 0.9267284150772319 1.0 17.847949176248726 -7.256002121619014 24.97484318459178 0.9799837094411331 0.8942068365616578 0.4586463114225614 0.04557231721844886 414.3622465773027 1903286.9233707925 0.017802002197101444 0.013390996891280203 5.5462300350238436e-08 7.256002121619014 -0.08577687287947533 SSS(ph)ETILSSLAGSDIVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SSSETILSSLAGSDIVK 17 0 Q01850 Q01850 CDR2 Cerebellar degeneration-related protein 2 1 S(0.043)S(0.092)S(0.864)ETILSSLAGSDIVK;S(0.12)S(0.12)S(0.581)ET(0.178)ILSSLAGSDIVK;S(0.092)S(0.092)S(0.809)ET(0.007)ILSSLAGSDIVK;S(0.008)S(0.008)S(0.982)ET(0.002)ILSSLAGSDIVK;SS(0.021)S(0.979)ETILSSLAGSDIVK 317.7 1.3822999999999996e-147 86901500.0 140066.0 130148.0 141929.7 171428.0 171825.0 151691.0 166933.0 160151.0 144217.0 129585.0 True False 163776.4073703992 143068.2333218325 145313.84231938468 161823.4449370747 138157.12470608312 143736.05692325634 151119.89774974034 155947.2059440106 146325.90079324093 153077.73470570426 1.069890455886765 0.9346116441877371 0.9492813739290965 1.0571324774839677 0.9025291951941516 0.938974287799545 0.9872101781508074 1.0187451901076467 0.9558927761411945 1.0 17.22390493124159 -10.686578409829467 4.366053927082968 1.0000041841506173 0.9773907965753766 0.012789471113283879 0.051849760537410784 2.485529791271056e-06 4.761223056777173e-07 0.048998119142657545 0.01188113784747346 2.0578873151080823e-11 10.686578409829467 -0.022613387575240673 SSS(ph)ETILSSLAGSDIVK ddPTM_PC-9_Lapatinib_30min_R1 3 SSSETILSSLAGSDIVK 17 0 Q01850 Q01850 CDR2 Cerebellar degeneration-related protein 2 1 S(0.03)S(0.03)S(0.939)ETILSSLAGSDIVK;S(0.005)S(0.123)S(0.867)ET(0.005)ILSSLAGSDIVK;S(0.129)S(0.034)S(0.81)ET(0.009)ILS(0.006)S(0.013)LAGSDIVK 235.26 2.7034e-37 46981600.0 184541.0 160931.0 188195.0 171209.0 168470.0 167771.0 154138.0 149787.0 167617.0 132381.0 True False 181909.41149932527 160558.3741570714 172722.33355370822 183800.2809964815 158560.9258247636 160595.82542330283 162118.51143697367 156746.6508443278 148738.20837474038 155262.87946340564 1.171622039524264 1.034106637156075 1.1124509229163024 1.183800542870918 1.0212416926232215 1.0343478491338565 1.0441549969784236 1.0095565107773998 0.95797661932321 1.0 17.24435342318715 -6.366886332500066 7.743299589501311 1.013858386258444 1.1178614402936191 0.6210930971706816 0.04356007087907256 0.21307439986520368 13.948030942801811 0.013851188120846998 0.015705325979163815 4.2964886365673656e-07 6.366886332500066 0.10400305403517507 SSS(ph)FAGGR ddPTM_PC-9_AZD4547_30min_R2 1 SSSFAGGR 8 0 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 S(0.041)S(0.214)S(0.745)FAGGR 120.31 0.0034216 4090200.0 16363.0 17136.0 19297.0 26476.0 28807.0 25324.0 23756.0 28952.0 27784.0 26566.0 True False 21566.093628456627 22674.87688725602 19041.109171564185 20372.367250122366 24807.64529501512 23740.486276706677 25870.237978530007 24478.13365077435 29252.60551783982 25635.932426061067 0.841244752483935 0.8844958907835595 0.7427507942799579 0.7946801743560594 0.9676903840562506 0.9260629136536688 1.0091397320204647 0.9548368767695098 1.1410782737163914 1.0 14.645879751713766 -6.7461515304311215 1.103589208569871 1.031273139565388 0.815988671819547 0.6792960248762498 0.06228025178765798 0.2982109236760659 0.7730653648034175 0.03359407205473464 0.030817758320848026 1.7941075324826773e-07 6.7461515304311215 -0.21528446774584098 SSS(ph)FAGGR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSFAGGR 8 0 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 SS(0.019)S(0.981)FAGGR;S(0.005)S(0.016)S(0.979)FAGGR 101.46 0.0045792 5698200.0 19521.1 20924.3 25299.0 23434.5 38237.0 45246.0 52863.0 47939.0 57045.0 47749.0 True False 19242.725534268688 20875.85106893515 23219.01387696411 25157.951305200317 35987.974836834386 43310.93405357755 55599.98747935445 50166.420949923646 50619.99138951932 56002.35102845684 0.3436056733491556 0.3727674050385379 0.4146078414666141 0.44923027057233084 0.6426154291013172 0.7733770682514682 0.9928152382585165 0.895791337839232 0.903890469951832 1.0 15.773199773610743 -6.582493742633469 1.1763443652013361 0.9499596750679093 0.36403021852904655 0.9753709628988944 0.03964907672310366 0.06521621133554115 0.19059878056290416 0.018846513475141213 0.0202006279326287 2.615208128096195e-07 6.582493742633469 -0.5859294565388629 down SSS(ph)FGSVSTSSNSSK ddPTM_PC-9_AZD4547_30min_R2 1 SSSFGSVSTSSNSSK 15 0 E5RG30;E5RJ65;E5RHF1;E5RGS8;E5RH07;E5RGQ6;A0A0C4DGW2;P57768-2;P57768 E5RG30 SNX16 Sorting nexin-16 1 S(0.001)S(0.067)S(0.932)FGSVSTSSNSSK 275.76 6.164999999999998e-75 16584000.0 79918.0 75909.0 99249.0 131660.0 121760.0 108950.0 89416.0 122490.0 95775.0 109410.0 True False 105330.26160233417 100445.09976859922 97932.89341185542 101307.82112672269 104855.72573058768 102137.33927685942 97373.85077825547 103561.98504018174 100837.47097146226 105579.58920181218 0.9976384867438589 0.9513685412869097 0.9275741092784483 0.9595398304976908 0.9931439071065066 0.9673966346054539 0.9222791215083088 0.980890206365798 0.9550848959898347 1.0 16.687971432206396 -10.821158177852956 3.149252034813971 1.0002413741243605 0.9607923395959735 0.1913978374560914 0.023582777454343666 16709364.685684435 22931605.325525075 38232.498063884734 0.005869823453892999 1.509530255988988e-11 10.821158177852956 -0.039449034528386995 SSS(ph)FGSVSTSSNSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSSFGSVSTSSNSSK 15 0 E5RG30;E5RJ65;E5RHF1;E5RGS8;E5RH07;E5RGQ6;A0A0C4DGW2;P57768-2;P57768 E5RG30 SNX16 Sorting nexin-16 1 S(0.004)S(0.119)S(0.877)FGSVSTSSNSSK;S(0.002)S(0.003)S(0.994)FGSVSTSSNSSK;S(0.001)S(0.004)S(0.994)FGS(0.001)VSTSSNSSK 227.91 1.7730999999999997e-24 18519100.0 70895.0 72329.0 75814.0 92541.0 109044.0 101449.0 95275.0 104948.0 89134.0 83405.0 True False 82896.12325992357 79509.34511429186 77621.69328619621 87356.22779197003 87677.61097890387 96128.83584924221 86249.86226873354 102193.22620159766 90437.4161250389 98525.66626638318 0.8413657719989214 0.8069911945515089 0.787832208881805 0.8866342253985432 0.8898961489065246 0.9756730351798822 0.875405014116224 1.0372244114066533 0.9179071763952742 1.0 16.588211979974034 -6.323848949778792 1.0902256007485354 0.9650516514923616 0.808710219451284 0.6584610461456251 0.045418224077041776 0.29476216246228576 0.7338389550263289 0.01925400200020312 0.027185248397162732 4.744069581499277e-07 6.323848949778792 -0.15634143204107764 SSS(ph)FGSVSTSSNSSK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSFGSVSTSSNSSK 15 0 E5RG30;E5RJ65;E5RHF1;E5RGS8;E5RH07;E5RGQ6;A0A0C4DGW2;P57768-2;P57768 E5RG30 SNX16 Sorting nexin-16 1 S(0.157)S(0.042)S(0.8)FGSVSTSSNSSK 297.45 2.8526999999999996e-104 16260000.0 100450.0 85839.0 102260.0 87541.0 99156.0 104540.0 88524.0 82288.0 127010.0 92795.0 True False 99017.56457972618 85640.24506943261 93852.57753501547 93979.0571682154 93323.83902819654 100069.0678946425 93107.33956874144 86111.4008871131 112704.79632540718 108834.49210843498 0.9097994823283789 0.7868851446847084 0.8623422199784552 0.8635043481856958 0.8574840312133334 0.9194609719402262 0.8554947771151069 0.7912142485244273 1.0355613752772064 1.0 16.73177632613232 -8.271874566332752 24.991639678925953 1.017780721562573 0.8561242385949659 0.7163535529768166 0.04077697784838263 404.9169662642751 969740.5107217947 0.037204384896129664 0.010014260033924723 5.347187754782145e-09 8.271874566332752 -0.16165648296760704 SSS(ph)FPYTTK ddPTM_PC-9_AZD4547_30min_R2 2 SSSFPYTTK 9 0 O43524;O43524-2 O43524 FOXO3 Forkhead box protein O3 1 SS(0.02)S(0.979)FPYT(0.001)TK;S(0.003)S(0.024)S(0.862)FPYT(0.09)T(0.021)K 128.91 0.0013151 27798000.0 46369.0 37225.0 57076.0 95846.0 65719.0 61524.0 69876.0 126575.0 97692.0 83940.0 True False 61113.37746488448 49257.253275449606 56319.1349472041 73750.18550593859 56595.05124251389 57676.89455410292 76094.82863225145 107015.74215414331 102855.79967782926 81001.28614934764 0.7544741617090566 0.6081045822486154 0.6952869222763283 0.9104816603770994 0.6986932422056324 0.7120491204023608 0.939427412201211 1.3211610239969651 1.2698045249329368 1.0 16.30565719503504 -7.542305003761538 3.5385926885101657 1.2191547423866835 0.7321602191905444 0.7912825798111264 0.10705601064394378 0.09847749511847739 2.637099468129721 0.054088341518959325 0.03078035584271963 2.868765148904488e-08 7.542305003761538 -0.4869945231961391 SSS(ph)FPYTTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSSFPYTTK 9 0 O43524;O43524-2 O43524 FOXO3 Forkhead box protein O3 1 S(0.178)S(0.032)S(0.727)FPYT(0.06)T(0.002)K;SS(0.018)S(0.982)FPYTTK;S(0.008)S(0.008)S(0.983)FPYTTK 121.61 0.0016064 16619700.0 88400.0 76960.0 81663.0 90002.0 134987.0 110164.0 119540.0 171458.0 121719.0 102629.0 True False 103364.37402041414 84600.08018907889 83610.1556286521 84959.47973042083 108537.26636228767 104386.80590736169 108216.30580534686 166957.40917476747 123498.91010527546 121234.8252892828 0.8525963870016117 0.6978199538557636 0.6896546056724779 0.7007844447970782 0.8952647566679209 0.8610298704046511 0.8926173279594211 1.3771406753495488 1.01867520170537 1.0 16.88744465390186 -7.5732722398708745 6.8074719844538185 1.149153726858566 0.7839700593706871 0.6378606049048241 0.11736684512839499 0.1249492530756873 13.007842054481127 0.056210410397274035 0.03231299932384443 2.6713313450452333e-08 7.5732722398708745 -0.365183667487879 SSS(ph)FPYTTK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSFPYTTK 9 0 O43524;O43524-2 O43524 FOXO3 Forkhead box protein O3 1 SS(0.014)S(0.985)FPYTTK 121.6 0.0016067 8081800.0 52723.0 35743.0 42286.0 35076.0 65072.0 49790.0 61576.0 45740.0 67135.0 70537.0 True False 51971.16035178594 35660.239279543355 38809.40830868037 37655.60605010589 61244.59289647431 47660.59776615888 64764.10398631805 47865.24738207949 59573.54933710891 82729.22646535544 0.6282079812936475 0.4310476575588049 0.4691136369434399 0.4551669060495198 0.7403017713712303 0.5761035102403348 0.7828443073070355 0.5785772383853249 0.7201028207613733 1.0 16.336109472280697 -11.584664718497066 0.12603934792496357 1.663397665503817 0.33869288614644877 0.6664301248345288 0.09689648435967702 33.944864463098014 0.597368006466843 7.564469753750927 1.0142497409936706 2.602167698300562e-12 11.584664718497066 -1.324704779357368 SSS(ph)FSELCHR ddPTM_PC-9_AZD4547_30min_R2 1 SSSFSELCHR 10 0 Q5T8I3-2;Q5T8I3 Q5T8I3-2 FAM102B Protein FAM102B 1 S(0.016)S(0.016)S(0.968)FSELCHR 163.12 0.00037685 3556100.0 10244.0 9038.2 27642.0 32625.0 24472.0 24875.0 19675.0 37659.0 17238.0 22201.0 True False 13501.378911563253 11959.62139836585 27275.44901903806 25103.810301225356 21074.485217468326 23319.562317685948 21426.036884474564 31839.666867729724 18149.165487925522 21423.749747458467 0.6302061530178649 0.5582412761232258 1.273140759230246 1.1717748105325707 0.9836973203053972 1.0884911648322622 1.000106757082353 1.4861855297533484 0.8471516752140267 1.0 14.386923393186088 -5.253309124721705 24.94625717382413 1.1172107025976648 0.5942236402167065 0.5949126751518445 0.16883647837036075 367.19810231229116 1126676.3398327213 0.041176930678955836 0.10499880741545553 5.580728249220699e-06 5.253309124721705 -0.5229870623809583 SSS(ph)FSELCHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSFSELCHR 10 0 Q5T8I3-2;Q5T8I3 Q5T8I3-2 FAM102B Protein FAM102B 1 S(0.019)S(0.019)S(0.963)FSELCHR;S(0.289)S(0.289)S(0.422)FSELCHR 97.163 0.0029760999999999998 4307400.0 25872.0 26139.0 31712.0 31856.0 38086.0 28118.0 33793.0 29809.0 28939.0 19887.3 True False 30251.61860470758 28733.907173367134 32468.134348429714 30071.211598545462 30623.321702638616 26643.442581089974 30591.88239986686 29026.545335246232 29362.17812779079 23492.71006221982 1.2877023776561738 1.2230988718315656 1.382051464579383 1.280023101587797 1.3035244389231195 1.1341153281390493 1.3021861811108668 1.2355554237195367 1.2498421020829797 1.0 14.519925528310551 -13.780023566267314 0.2359076090832703 1.506694300284393e-13 1.2961281326932688 0.6554195297267216 0.05904394264136906 69.74767293861812 0.9582859653583016 33.32621055045135 0.09742509092137779 1.6594968551591797e-14 13.780023566267314 1.296128132693118 SSS(ph)FSELCHR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSFSELCHR 10 0 Q5T8I3-2;Q5T8I3 Q5T8I3-2 FAM102B Protein FAM102B 1 S(0.256)S(0.256)S(0.487)FSELCHR 163.46 0.00039138 4853500.0 17217.0 20361.0 34901.0 25381.0 29043.0 27023.0 18186.0 21656.0 34478.0 21903.0 True False 16971.48242278888 20313.85535547612 32031.57450175599 27247.603408533956 27334.74784073493 25867.289283689726 19127.582095218604 22662.216819114852 30594.72457056441 25688.904366087027 0.6606541945476517 0.7907637891436612 1.2469031004701852 1.0606759642308696 1.0640682627485136 1.006944045376968 0.744585359602557 0.8821791889665863 1.1909703946328578 1.0 14.648857740036519 -5.036827125761344 9.514782430092637 1.0129788820696346 0.6925598224786675 0.4510380066680697 0.13478034072833525 0.39150312454262054 100.49342420606209 0.03671604747771807 0.10027012350304694 9.186982185586677e-06 5.036827125761344 -0.32041905959096706 SSS(ph)FSLPSR ddPTM_PC-9_AZD4547_30min_R2 1 SSSFSLPSR 9 0 Q14153-2;Q14153 Q14153-2 FAM53B Protein FAM53B 1 S(0.337)S(0.061)S(0.512)FS(0.09)LPSR 78.098 0.022097 11117000.0 23370.0 25881.0 30977.0 48473.0 40622.0 37137.0 26985.0 32799.0 27152.0 31282.0 True False 30801.173873802527 34246.52711946038 30566.224739987778 37298.29875038458 34982.336486760316 34814.81751927245 29386.612723128146 27730.668196039907 28587.199288093365 30186.826701499747 1.0203514989627 1.134485829136818 1.0125683312870108 1.2355819682276017 1.158861010224116 1.1533116038839146 0.9734912852455656 0.9186347564867489 0.9470090901165538 1.0 14.881631485436076 -7.327161514396054 5.391297371863937 0.9502244470816089 1.1220494910353398 0.5946228778126348 0.06439897639145613 0.15350844269066757 8.816822182584277 0.028067627822157087 0.0188058874917964 4.708022021939506e-08 7.327161514396054 0.17182504395373088 SSS(ph)FSLPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSSFSLPSR 9 0 Q14153-2;Q14153 Q14153-2 FAM53B Protein FAM53B 1 S(0.002)S(0.002)S(0.893)FS(0.103)LPSR;S(0.031)S(0.02)S(0.815)FS(0.132)LPS(0.001)R;S(0.002)S(0.008)S(0.869)FS(0.122)LPSR 130.98 0.0012483 18898300.0 100561.0 106538.0 119646.0 134877.0 143636.0 142336.0 125159.0 128539.0 116767.0 110846.0 True False 117583.99112971523 117114.38855488705 122498.81439998151 127320.27896713393 115491.5568996537 134871.6495917926 113303.03344730988 125164.98744832803 118474.49647353886 130941.50234354705 0.8979887127093887 0.8944023587541997 0.9355232085132587 0.9723447240821155 0.8820087965436824 1.0300145269292402 0.8652950471733577 0.9558847669239096 0.9047895002968661 1.0 16.998562911180564 SSS(ph)FSLPSR ddPTM_PC-9_Lapatinib_30min_R1 3 SSSFSLPSR 9 0 Q14153-2;Q14153 Q14153-2 FAM53B Protein FAM53B 1 S(0.014)S(0.009)S(0.841)FS(0.136)LPSR;S(0.016)S(0.003)S(0.867)FS(0.115)LPSR;S(0.004)S(0.002)S(0.813)FS(0.181)LPSR 128.03 0.0013430999999999998 24282200.0 151642.0 122384.0 164190.0 123315.0 131095.0 141981.0 128365.0 149760.0 143560.0 117638.0 True False 149479.55727226275 122100.62736725032 150690.93199172872 132383.99646678078 123384.24984268671 135908.80360387653 135011.11160523127 156718.3963257595 127390.76104618111 137971.5715572183 1.0834083832282215 0.8849694613836726 1.0921882695902725 0.95950198271011 0.8942729900812787 0.9850493262484415 0.9785429714355375 1.1358745468863976 0.9233116620212649 1.0 17.074011511016593 SSS(ph)FVLPK ddPTM_PC-9_AZD4547_30min_R2 2 SSSFVLPK 8 0 Q8WYP3;Q8WYP3-2 Q8WYP3 RIN2 Ras and Rab interactor 2 1 S(0.001)S(0.025)S(0.975)FVLPK;S(0.012)S(0.081)S(0.907)FVLPK 92.051 0.0082649 50564000.0 173881.0 160928.0 225700.0 310000.0 267310.0 230920.0 183983.0 269240.0 201003.0 224410.0 True False 229171.54105051982 212944.828881439 222707.07053023984 238534.28945225605 230198.62060646663 216480.53589547865 200357.1305777023 227635.14451970448 211627.60822424272 216553.47420508796 1.0582676721846627 0.9833360081758311 1.0284160591176852 1.1015029443783066 1.063010517155019 0.9996631856871516 0.9252085717542133 1.0511729047769587 0.9772533504764732 1.0 17.724363792435668 -6.8639070143844965 6.06292784109131 0.9887251144944988 1.0451920397534225 0.33247672854333554 0.03998843744914241 0.2783704472882512 14.18887076793125 0.014861869366703993 0.01312624694258966 1.3680216976629574e-07 6.8639070143844965 0.056466925258923606 SSS(ph)FVLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSSFVLPK 8 0 Q8WYP3;Q8WYP3-2 Q8WYP3 RIN2 Ras and Rab interactor 2 1 S(0.005)S(0.023)S(0.971)FVLPK;S(0.004)S(0.027)S(0.97)FVLPK;S(0.124)S(0.026)S(0.85)FVLPK 87.149 0.011942 38575000.0 340440.0 331760.0 357840.0 397520.0 466990.0 379130.0 359970.0 363200.0 306751.0 302747.0 True False 398069.7680035045 364694.94027454284 366372.2627157576 375248.2431772294 375486.66181576374 359247.7553797798 325871.0356428876 353666.3848422105 311236.65305912326 357632.63455606723 1.1130689135728127 1.0197473749207537 1.024437445901823 1.04925615539261 1.0499228133412906 1.0045161449701518 0.9111893159509741 0.9889097097674543 0.8702691616649142 1.0 18.44811886521977 -7.026656159776209 3.5752422827998087 0.9419417142691048 1.047410599177105 0.599383699383901 0.041722835661494775 0.16244416331202824 4.369017385550338 0.015478638522009853 0.01240512426970064 9.404676041926586e-08 7.026656159776209 0.10546888490800022 SSS(ph)FVLPK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSFVLPK 8 0 Q8WYP3;Q8WYP3-2 Q8WYP3 RIN2 Ras and Rab interactor 2 1 SS(0.003)S(0.996)FVLPK;S(0.001)S(0.03)S(0.968)FVLPK 99.01299999999999 0.0053299 30906000.0 297906.0 251536.0 303295.0 225531.0 257917.0 262382.0 247891.0 234135.0 287087.0 213263.0 True False 293657.8058107298 250953.58384632578 278359.255852557 242117.3020893609 242746.82914433168 251160.5335023157 260725.58304002162 245013.76685184057 254752.23889986725 250125.22539491506 1.1740431431779121 1.0033117749323477 1.112879580270499 0.9679843434707127 0.9705011909976938 1.0041391591182618 1.0423802022701627 0.979564402050996 1.0184987879477039 1.0 17.93229103662172 -1.5228795901004968 0.9392376282615222 1.003589960884143 105.18267876351285 0.5761638985661242 0.04119646322563986 808.7795847366784 1.4959081712905893 0.013242780517579123 180932.05550406536 0.029999941641947615 1.5228795901004968 104.17908880262871 SSS(ph)HLSPSEEVR ddPTM_PC-9_AZD4547_30min_R2 1 SSSHLSPSEEVR 12 0 A0A2R8YH03;Q5VWN6;Q5VWN6-2 A0A2R8YH03 FAM208B Protein FAM208B 1 S(0.051)S(0.067)S(0.787)HLS(0.087)PS(0.008)EEVR 74.392 0.020885 8780600.0 17834.0 19669.0 20990.0 30739.0 25929.0 22197.0 27186.0 22701.0 18094.0 21892.0 True False 23504.841029755877 26026.619601741255 20711.65888537763 23652.598462815826 22329.205917118987 20809.018081032158 29605.50133373956 19193.082067084433 19050.411900366875 21125.567743406194 1.1126252943943866 1.2319962198348395 0.9804072078414198 1.1196195411220784 1.0569754237297824 0.9850158033043709 1.4014061867274625 0.9085238465638427 0.9017704107059075 1.0 14.366702493469253 SSS(ph)HLSPSEEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSHLSPSEEVR 12 0 A0A2R8YH03;Q5VWN6;Q5VWN6-2 A0A2R8YH03 FAM208B Protein FAM208B 1 S(0.01)S(0.03)S(0.955)HLS(0.004)PSEEVR 72.49600000000001 0.024891999999999997 3681500.0 16159.0 20310.0 18445.0 19693.0 20449.0 17491.0 19849.0 20308.0 17763.0 15941.0 True False 18894.399545202137 22326.2425758861 18884.79875305204 18589.665055567435 16442.16524437475 16573.74116885427 17968.759025684532 19774.93651810461 18022.750270705557 18830.977111113436 1.0033679842375929 1.185612538539483 1.0028581438775601 0.9871853672742459 0.8731445610791548 0.8801317675158228 0.9542127803384111 1.0501280098967396 0.9570799308161821 1.0 14.200820240722207 -5.511201089003213 3.9040594481834505 0.9538799918240526 1.096291925062331 0.40974191302225926 0.06447091744919348 0.20039249773776383 6.819940915578417 0.0182847616955727 0.03730599969605754 3.0817606890173607e-06 5.511201089003213 0.1424119332382785 SSS(ph)KESLVR ddPTM_PC-9_AZD4547_30min_R2 1 SSSKESLVR 9 1 Q13439-3;Q13439-4;Q13439;Q86W71;Q13439-5;E7EVX2 Q13439-3;Q13439-5 GOLGA4 Golgin subfamily A member 4 1 SS(0.001)S(0.996)KES(0.003)LVR 93.62299999999999 0.029505 95207000.0 152690.0 147120.0 174130.0 244530.0 216360.0 191290.0 201640.0 202900.0 175310.0 185570.0 True False 201242.24385070216 194673.6629115956 171820.92242547913 188157.38645083943 186322.1486454497 179328.60606030747 219585.56937156047 171546.46717816096 184576.5286975417 179073.2507831124 1.1237984621971269 1.0871174899671527 0.95950077230453 1.0507286019994657 1.0404800707567259 1.0014259822507179 1.2262332225013062 0.9579681299577925 1.0307319931389123 1.0 17.450190324073994 -9.091788327667032 0.007077288976716166 3.6305843585381605e-06 2.0590319328859352 0.06071343070368174 0.07495587313138148 18983.037700642344 53.78363514058984 7968.538917691155 7675.388923096811 8.09490343424827e-10 9.091788327667032 2.0590283023015767 SSS(ph)KGSVEEIMSQPK ddPTM_PC-9_AZD4547_30min_R2 1 SSSKGSVEEIMSQPK 15 1 A0A087WVA8;Q8IWB9;Q8IWB9-2;J3KRZ8 A0A087WVA8 TEX2 Testis-expressed sequence 2 protein 1 S(0.03)S(0.147)S(0.584)KGS(0.239)VEEIMSQPK 83.792 0.009759 4236300.0 22363.0 24593.0 30409.0 32376.0 31231.0 26992.0 36102.0 31723.0 26937.0 32719.0 True False 29473.96882070374 32542.206307673154 30005.756791112377 24912.21340421371 26895.114736300802 25304.185973024287 39315.008061158886 26820.9392720197 28360.83482702458 31573.51776888851 0.9335028499658156 1.0306804121693136 0.9503456982762639 0.7890224201992904 0.8518250938386838 0.801437019411191 1.2451893497878967 0.849475800205201 0.8982475451300647 1.0 14.946427387270356 SSS(ph)LDALGPTR ddPTM_PC-9_AZD4547_30min_R2 2 SSSLDALGPTR 11 0 Q9H425;Q9H425-2;Q9H425-3;E5RI90 Q9H425 C1orf198 Uncharacterized protein C1orf198 1 S(0.033)S(0.022)S(0.945)LDALGPTR;S(0.068)S(0.034)S(0.898)LDALGPTR 117.95 0.0011119 14017400.0 29506.0 50979.0 66282.0 87871.0 97439.0 80896.0 69682.0 106129.0 67587.0 80649.0 True False 38888.29423707392 67456.96480132024 65403.05737211048 67613.69854341671 83911.2767695692 75837.56033171961 75883.56300807913 89729.2016518039 71159.51083840484 77825.50305764502 0.49968574193821175 0.8667719725673363 0.8403807852506486 0.8687858849217529 1.0781976790746406 0.9744564102020266 0.9750475104783132 1.1529536993206695 0.9143469433881756 1.0 16.247955376736023 -4.379513237236792 0.7254570084726023 1.0168380952126272 1.1500047240156042e-16 0.759450686737235 0.08208324900534338 2.3078510542793365 0.613796663374169 0.03220737589715162 2.1907004243163777 4.1733687790013096e-05 4.379513237236792 -1.016838095212627 down SSS(ph)LDALGPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSLDALGPTR 11 0 Q9H425;Q9H425-2;Q9H425-3;E5RI90 Q9H425 C1orf198 Uncharacterized protein C1orf198 1 S(0.029)S(0.135)S(0.837)LDALGPTR;S(0.149)S(0.019)S(0.832)LDALGPTR 105.25 0.0025815 15963800.0 40870.0 42511.0 68156.0 71768.0 89170.0 69422.0 76165.0 80026.0 65492.0 54521.0 True False 47788.48378070494 46731.21113458855 69781.09752306936 67747.07163499533 71697.77861220087 65781.3881095536 68950.09981315237 77925.40229455578 66449.6966013088 64405.22571200145 0.7419969925173309 0.725581047468956 1.0834694972595393 1.0518878070226396 1.1132292111327933 1.0213672474917779 1.070566853091612 1.209923595998437 1.0317438665373138 1.0 15.974890130046596 -5.261821245664541 24.990738406393245 1.079054969742721 0.733788989212294 0.8552077307357311 0.0557446976917498 10.316103290718601 675179.316073665 0.01423156061588985 0.03290705120416826 5.472411594024549e-06 5.261821245664541 -0.345265980530427 SSS(ph)LDALGPTR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSLDALGPTR 11 0 Q9H425;Q9H425-2;Q9H425-3;E5RI90 Q9H425 C1orf198 Uncharacterized protein C1orf198 1 S(0.189)S(0.029)S(0.782)LDALGPTR;S(0.227)S(0.034)S(0.739)LDALGPTR 91.09299999999999 0.00838 16761500.0 83931.0 65541.0 137059.0 85333.0 85400.0 84372.0 69569.0 70834.0 121630.0 83857.0 True False 82734.12854893973 65389.24384132705 125790.53808303979 91608.67348254306 80376.93990285993 80763.60624073834 73170.94241626876 74125.20623223046 107930.74857931864 98351.57071757088 0.8412080045627472 0.6648520543622087 1.278988603489246 0.9314408790237737 0.8172410396339536 0.821172510530222 0.7439732978580331 0.7536758761595224 1.0973973043018865 1.0 16.585660472707602 -3.333487831169626 15.60478871985501 0.885032836731367 0.45704346257060297 0.0 0.1766061931872989 0.0 0.0 0.04084865548186192 0.0 0.00046399379079808663 3.333487831169626 -0.42798937416076405 SSS(ph)LDGEHHDGYHR ddPTM_PC-9_AZD4547_30min_R2 2 SSSLDGEHHDGYHR 14 0 Q9C0J8 Q9C0J8 WDR33 pre-mRNA 3 end processing protein WDR33 1 S(0.304)S(0.304)S(0.393)LDGEHHDGYHR;S(0.31)S(0.31)S(0.38)LDGEHHDGYHR 71.08 0.022365 13696500.0 21254.2 16132.8 18569.2 27310.8 27771.8 27472.1 18451.4 23997.9 21336.6 24002.9 True False 28012.593485176458 21347.412105901232 18322.96027510026 21014.71700765381 23916.16494616242 25754.265244128637 20093.53885490186 20289.575971881644 22464.40911646777 23162.565776914158 1.2093907797164796 0.9216341709076951 0.791059179348884 0.907270688837025 1.032535219824367 1.111891726166088 0.8675005631253875 0.8759640951394086 0.9698584057064079 1.0 14.499507452764457 -8.330389895647034 0.004964939025915928 5.431046255853066e-08 1.9037535078651633 0.0017728497173532531 0.11816522024990436 48912.81717700716 194.78746278425461 37503.14515170442 37171.88618996257 4.673154121273332e-09 8.330389895647034 1.9037534535547007 SSS(ph)LDGEHHDGYHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSLDGEHHDGYHR 14 0 Q9C0J8 Q9C0J8 WDR33 pre-mRNA 3 end processing protein WDR33 1 S(0.305)S(0.305)S(0.391)LDGEHHDGYHR 95.57 0.0027311 4123900.0 4301.5 4850.4 3648.0 5396.3 7434.8 4057.0 5203.2 6489.3 5775.7 4579.1 True False 5029.6589915023815 5331.915656823137 3734.9821551170407 5093.962806040652 5978.004311158371 3844.243778059679 4710.315228094199 6318.962750981694 5860.158685949109 5409.254581864344 0.9298247873866695 0.9857024800976273 0.6904800095080288 0.9417125278442665 1.1051438272476357 0.7106790260802864 0.8707882309489582 1.1681762533727542 1.0833579002912002 1.0 12.401214082939244 -7.751882252971381 24.953248576915577 1.094325310681437 0.8898734573120259 0.34763144985395755 0.12104218827706599 204.17038097345602 533083.8246558711 0.05877187120107152 0.033365206979288374 1.7705889398409776e-08 7.751882252971381 -0.20445185336941107 SSS(ph)LDGEHHDGYHR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSLDGEHHDGYHR 14 0 Q9C0J8 Q9C0J8 WDR33 pre-mRNA 3 end processing protein WDR33 1 S(0.306)S(0.306)S(0.389)LDGEHHDGYHR 76.358 0.01415 7531500.0 1851.8 5305.8 5685.1 3616.4 6785.0 6622.3 5134.9 5507.7 5035.9 3875.3 True False 1825.3929924214708 5293.514746087384 5217.693023120627 3882.362119956749 6385.919639823244 6339.079666335288 5400.759996741336 5763.607848847379 4468.703911622056 4545.140441487332 0.4016142110284577 1.164653725057428 1.1479717932353288 0.8541786925920163 1.4049994102566263 1.3946939039491846 1.188249310724052 1.2680813548109682 0.9831828013128977 1.0 12.150109157982891 -4.761411552833363 8.524800156430153 1.1715790521073517 0.39448429187664136 0.6456842892534258 0.1673585159260772 0.05518758758935893 44.46998159969582 0.04273913544415122 0.24699242932182375 1.7321617619194393e-05 4.761411552833363 -0.7770947602307103 SSS(ph)LDMNR ddPTM_PC-9_AZD4547_30min_R2 4 SSSLDMNR 8 0 H0YDT0;Q96D71-4;E9PMG1;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 SS(0.002)S(0.998)LDMNR;S(0.102)S(0.347)S(0.551)LDMNR;S(0.005)S(0.019)S(0.976)LDMNR;S(0.004)S(0.015)S(0.981)LDMNR 120.31 0.0033269 282758400.0 122906.0 127660.0 172374.0 228780.0 203112.0 172248.0 156190.0 204427.0 148211.0 188692.0 True False 161987.55139638713 168923.59847263657 170088.20813282928 176038.30561576496 174913.40476832396 161477.30533052358 170090.60741987714 172837.50441513 156045.13088124647 182085.9505133748 0.8896213625470716 0.9277135220832351 0.934109455744834 0.9667868669682694 0.9606090106082952 0.8868191361016762 0.934122632417944 0.9492083487376723 0.856986112554491 1.0 17.47426008479863 -5.785595461786143 0.0045937941205205605 1.8500188254419558 9.511782110961062e-08 0.10822071275936884 0.03826705002860123 69159.91624334129 71.85889941036262 14140.895026413682 14800.801123217112 1.6383418995953285e-06 5.785595461786143 -1.8500187303241347 SSS(ph)LDMNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 SSSLDMNR 8 0 H0YDT0;Q96D71-4;E9PMG1;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 SS(0.014)S(0.986)LDMNR;SS(0.009)S(0.991)LDMNR;S(0.001)S(0.019)S(0.98)LDMNR;S(0.047)S(0.023)S(0.93)LDMNR;S(0.296)S(0.079)S(0.626)LDMNR;S(0.001)S(0.012)S(0.987)LDMNR;S(0.015)S(0.065)S(0.92)LDMNR 112.11 0.0037351999999999997 495914000.0 398905.0 383400.0 451828.0 467134.0 553102.0 487315.0 443113.0 466782.0 441535.0 379930.0 True False 466431.7377671188 421461.41819767165 462601.29308723164 440961.9964488628 444725.6335759285 461759.3435309711 401138.12877969496 454529.4670964107 447991.6140728471 448808.3014757748 1.039267179848043 0.9390677864286803 1.0307324788024255 0.9825174690371997 0.9909033146525552 1.028856511817207 0.8937850023287662 1.0127474594427588 0.9981803201940734 1.0 18.77573983573817 SSS(ph)LDMNR ddPTM_PC-9_Lapatinib_30min_R1 6 SSSLDMNR 8 0 H0YDT0;Q96D71-4;E9PMG1;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 SS(0.002)S(0.998)LDMNR;S(0.001)S(0.068)S(0.931)LDMNR;SS(0.002)S(0.997)LDMNR;S(0.089)S(0.088)S(0.822)LDMNR;S(0.001)S(0.012)S(0.987)LDMNR;S(0.023)S(0.089)S(0.887)LDMNR 131.11 0.0033068000000000004 421034000.0 582894.0 474356.0 548376.0 469933.0 500771.0 499905.0 445302.0 441933.0 548532.0 377840.0 True False 574581.8246703306 473257.6578263465 503290.6420725757 504493.4404705331 471316.6343336666 478525.2284854724 468357.55868057965 462466.8205357356 486750.5498619658 443149.14055984624 1.2965879251044936 1.0679421768221486 1.1357139075949703 1.1384281143661665 1.0635621085448463 1.0798288537374443 1.0568847275409057 1.043591825432595 1.0983899218376827 1.0 18.75743278977592 -2.5116446225111995 1.4720748477201315 1.0764299823462176 199.99997937637522 0.7125159284221477 0.041243129627624664 684.368831165691 2.1414787699399143 0.011533733616001327 459057.0425337515 0.0030786149746403787 2.5116446225111995 198.923549394029 SSS(ph)LESLQTAVAEVTLNGDIPFHRPR ddPTM_PC-9_AZD4547_30min_R2 2 SSSLESLQTAVAEVTLNGDIPFHRPR 26 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.064)S(0.064)S(0.869)LES(0.003)LQTAVAEVTLNGDIPFHRPR;S(0.054)S(0.054)S(0.65)LES(0.221)LQT(0.021)AVAEVTLNGDIPFHRPR 107.7 3.2448000000000005e-10 1575700.0 617.4 1408.3600000000001 2120.3 1745.13 1441.5900000000001 2025.0900000000001 1074.0700000000002 2359.5 507.14 2876.34 True False 813.7203572822285 1863.5848280191344 2092.1834366205912 1342.817240489729 1241.450112154714 1898.4608021677436 1169.660149250705 1994.8934909160703 533.9463850531698 2775.6402120897596 0.2931649259648045 0.6714072018059051 0.7537660780052619 0.48378649172211396 0.4472662223105764 0.6839722215792536 0.42140193248247987 0.7187147247063874 0.19236873090664924 1.0 11.43860485766693 -10.786837223152927 4.535795714670865 1.000212182372329 0.5346429547357979 0.3909979050430543 0.1792788146659607 0.00036569288954928415 5.934271269068923e-05 0.16405739064344194 0.039771723972196533 1.6336641428006214e-11 10.786837223152927 -0.46556922763653097 SSS(ph)LESLQTAVAEVTLNGDIPFHRPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSLESLQTAVAEVTLNGDIPFHRPR 26 1 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10;F5GZI3 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 S(0.19)S(0.19)S(0.615)LES(0.004)LQT(0.001)AVAEVTLNGDIPFHRPR 66.014 0.00021688 1264300.0 702.75 1595.9 1790.2 2067.4 1692.5 1629.5 1852.7 1933.0 1831.5 1883.8 True False 692.7286561314332 1592.204791601803 1643.0166663718392 2219.4434926442254 1592.9504775830267 1559.8100835500284 1948.623740669279 2022.814236763437 1625.2171834499893 2209.4123199942815 0.31353525544440985 0.720646290053241 0.7436442041637985 1.0045401994725773 0.7209837942730172 0.7059841521812757 0.8819647301841435 0.9155440197638948 0.7355879971983662 1.0 11.109446963881298 -4.639591652402424 1.798531637100099 0.8355028180329422 4.221668398592817e-13 0.6907441718452696 0.1056053614026902 0.7674977764366127 1.8910265388691663 0.02838335542047803 1.231539262102296 2.2930226657131343e-05 4.639591652402424 -0.83550281803252 SSS(ph)LGNLK ddPTM_PC-9_AZD4547_30min_R2 4 SSSLGNLK 8 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6;H0YGH8 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.047)S(0.047)S(0.906)LGNLK;S(0.052)S(0.198)S(0.75)LGNLK;S(0.084)S(0.028)S(0.888)LGNLK;SS(0.002)S(0.998)LGNLK 83.883 0.014425 46532000.0 166267.0 199014.0 227973.0 254242.0 246205.0 274689.0 230023.0 284551.0 239062.0 227792.0 True False 219136.44743155915 263341.383569116 224949.92906508796 195630.4348997438 212023.68555764933 257512.6534063444 250494.60138640416 240580.1812814827 251698.32926525403 219817.0714144881 0.996903680052922 1.1980024202604276 1.02335058700205 0.8899692532563229 0.964546039092007 1.171486144134717 1.1395593607653445 1.0944563119387738 1.1450354044188427 1.0 17.74594390753304 -6.761485711077224 24.999999999997275 1.1178517074565406 1.0183132342083268 0.2411614053206793 0.0840584661615017 1.9700646900455387 1062106.2905205926 0.030761796773657393 0.028894973651166896 1.7318660107340264e-07 6.761485711077224 -0.09953847324821385 SSS(ph)LGNLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSSLGNLK 8 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6;H0YGH8 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.002)S(0.007)S(0.991)LGNLK;S(0.001)S(0.031)S(0.968)LGNLK;SS(0.011)S(0.989)LGNLK 94.40899999999999 0.0067423000000000005 35803800.0 211907.0 278095.0 286800.0 255854.0 298553.0 212556.0 278860.0 220133.0 228601.0 188929.0 True False 247778.66974597116 305702.4337341717 293638.3996950572 241519.3298698601 240053.68283064268 201409.1891765474 252444.36202843362 214354.74200019301 231943.8571543973 223180.332138859 1.1102173178584906 1.3697552593656364 1.3157001644408362 1.0821712090633098 1.0756041113931374 0.9024504410685886 1.1311227992588837 0.9604553409608924 1.039266564986048 1.0 17.767850369095115 -5.890104431081755 3.7713572691519204 1.0198986830132448 1.2753778729391783 0.6263263523546589 0.08502186550442457 0.13799588858973774 3.716101088102428 0.023936753577621296 0.0371361764754392 1.2879398145766844e-06 5.890104431081755 0.25547918992593344 SSS(ph)LGNLK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSLGNLK 8 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6;H0YGH8 Q86W92-2 PPFIBP1 Liprin-beta-1 1 S(0.004)S(0.106)S(0.89)LGNLK;SS(0.01)S(0.99)LGNLK 97.59700000000001 0.0057644 24671600.0 99177.0 120089.0 128300.0 128331.0 141820.0 132309.0 131509.0 128035.0 132966.0 107478.0 True False 97762.71779316563 119810.941298746 117751.66925232222 137768.88983966652 133478.42642884783 126650.45249734311 138317.892541521 133983.9735147472 117989.96888594673 126055.42909456675 0.7755534092849271 0.9504623653207659 0.9341261229136346 1.0929230960477898 1.0588867721731554 1.004720331421267 1.0972783444158916 1.0628972863535489 0.9360165582192472 1.0 16.943698729556196 -4.430588037458511 1.0322552975780688 1.0383003296014064 0.4614367847765028 0.6812370848914022 0.05237262257187058 1.9157838748613245 1.0200594718966132 0.01662411487857514 1.448333452954201 3.710325084817124e-05 4.430588037458511 -0.5768635448249035 SSS(ph)LGNLKK ddPTM_PC-9_AZD4547_30min_R2 1 SSSLGNLKK 9 1 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6;H0YGH8 Q86W92-2 PPFIBP1 Liprin-beta-1 1 SS(0.126)S(0.874)LGNLKK 66.56 0.022057 250710000.0 125450.0 100380.0 156380.0 222020.0 186540.0 165900.0 157680.0 166890.0 128160.0 174320.0 True False 165340.4904779001 132825.87196211255 154306.29902312302 170836.7191748064 160642.14091478163 155526.24677403417 171713.21453336446 141100.9852506815 134934.27595617456 168217.1098588787 0.9828993650919822 0.789609761299212 0.9173044237448509 1.0155727875608216 0.9549690935098581 0.9245566453050393 1.020783288200699 0.8388028148210038 0.8021435873519293 1.0 17.359964928265036 -10.45188244135934 8.45868362482849 0.9999997755828044 0.9176918857788338 0.09225295080391249 0.07866213460677594 1.124157921018967e-10 0.0 0.07885000590472808 0.019123935466221775 3.532787854514809e-11 10.45188244135934 -0.08230788980397064 SSS(ph)LGSNR ddPTM_PC-9_AZD4547_30min_R2 2 SSSLGSNR 8 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 S(0.011)S(0.041)S(0.619)LGS(0.33)NR;S(0.003)S(0.012)S(0.958)LGS(0.027)NR 86.344 0.012546 11794000.0 172659.0 144667.0 251140.0 326230.0 283240.0 302740.0 271700.0 321440.0 292280.0 328450.0 True False 227560.97046969886 191427.77863262538 247809.7195080393 251022.7137032565 243917.01507828222 283809.6199419599 295880.77364735625 271768.83395637246 307729.3240985535 316951.06547239865 0.7179687821226642 0.6039663515480299 0.7818548239889718 0.7919920172191898 0.7695731033897517 0.8954367120329974 0.9335219403864813 0.8574472956931554 0.9709048418559483 1.0 18.27390059224676 -6.055594414216436 0.35365207446100033 0.996464676695515 0.5635614096000237 0.8223447694877613 0.04906552104419818 1.065501148403174 0.20432667885369196 0.05205297891757078 0.1830620161732927 8.79843815693221e-07 6.055594414216436 -0.4329032670954913 SSS(ph)LGSNR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSLGSNR 8 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 S(0.012)S(0.04)S(0.702)LGS(0.245)NR 82.831 0.038826 0.0 105720.0 104010.0 139180.0 132180.0 162170.0 138040.0 147080.0 151550.0 168970.0 134000.0 True False 104212.41341332643 103769.17123535555 127737.15765033693 141900.9581395537 152631.47943848703 132136.35098695676 154695.08273203278 158591.56626047578 149938.8192670185 157161.72145622323 0.6630903024459068 0.6602700089681828 0.8127752512937294 0.9028977083270219 0.9711746475174741 0.8407667577232718 0.9843050922238878 1.0090979202251282 0.9540415940836036 1.0 17.26189034985785 -5.50561588171571 1.3383999207170014 0.9594888513028791 0.6311356758766183 0.8730546824404963 0.04473643034743171 0.17741707111818444 0.5741303320359104 0.01506154417528506 0.055097692320085975 3.121649353159907e-06 5.50561588171571 -0.32835317542626075 SSS(ph)LGSTPHEELER ddPTM_PC-9_AZD4547_30min_R2 1 SSSLGSTPHEELER 14 0 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 S(0.045)S(0.045)S(0.907)LGS(0.003)TPHEELER 98.507 0.0013808 3750000.0 15957.0 15047.0 19450.0 30708.0 23109.0 22029.0 18806.0 20690.0 19518.0 20173.0 True False 21030.994073781232 19910.648489877527 19192.080291595757 23628.745033870597 19900.714240375743 20651.523147590087 20479.697567950632 17492.83590890167 20549.68163321326 19466.74941018332 1.0803546925394556 1.0228029379913832 0.9858903449774783 1.213800236289582 1.0222926191244548 1.0608614059000006 1.0520347869294204 0.8986007648380643 1.0556298434942324 1.0 14.248724380129174 -7.555130618067585 24.90867011271509 0.981332637939466 1.0631537340573274 0.2216556287107625 0.06706418799284204 274.0664049089876 211663.1615341007 0.03090647453049153 0.0178439853674977 2.7852833430115758e-08 7.555130618067585 0.08182109611786137 SSS(ph)LGSTPHEELER ddPTM_PC-9_Lapatinib_30min_R1 1 SSSLGSTPHEELER 14 0 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 S(0.039)S(0.039)S(0.922)LGSTPHEELER 121.45 4.0861e-05 2975300.0 29401.0 30553.0 44663.0 37776.0 38755.0 40249.0 38826.0 41534.0 43659.0 35419.0 True False 28981.736348516923 30482.25640567071 40990.98054416572 40554.17305704185 36475.5070952616 38527.64409500157 40836.22030292299 43463.821267321604 38741.66367034838 41541.12695714911 0.6976637003231144 0.7337850135147767 0.9867565842989556 0.9762415232228695 0.8780577169436726 0.9274578452034766 0.9830311138416334 1.0462841153095297 0.9326098377232651 1.0 15.342252734716999 -5.231978737351722 6.094150780227594 0.9645228519542838 0.7119811659001486 0.8385864255325859 0.043988585872649186 0.07207267545192482 8.95421439700679 0.012151673273856975 0.031676880384144776 5.861668619883084e-06 5.231978737351722 -0.2525416860541352 SSS(ph)LIQLTSQNSSPNQQR ddPTM_PC-9_AZD4547_30min_R2 4 SSSLIQLTSQNSSPNQQR 18 0 H7C419;O95639 H7C419 CPSF4 Cleavage and polyadenylation specificity factor subunit 4 1 S(0.004)S(0.004)S(0.991)LIQLT(0.001)SQNSSPNQQR;SSS(1)LIQLTSQNSSPNQQR;SS(0.001)S(0.999)LIQLTSQNSSPNQQR;SSS(1)LIQLTSQNSSPNQQR 400.72 0.0 58746400.0 61080.2 58945.0 97863.0 126980.0 112650.0 92396.0 97828.0 132309.0 94024.0 92240.0 True False 80502.43305291532 77997.81851770003 96565.27267745172 97706.72282144359 97010.49198054145 86618.46351376521 106534.50248205218 111863.6842083551 98993.91668619956 89010.70567567096 0.9044129292294648 0.8762745775985792 1.0848725661080296 1.0976963060764664 1.0898744285212092 0.9731241074458797 1.1968729117847106 1.2567441563260235 1.1121574189840098 1.0 16.4416912448009 -5.304340030459974 4.584342755803333 1.1105940361338575 0.8884444662844623 0.5367335654101226 0.07825796663203134 0.14923391827544005 7.279924990975881 0.02219748983553118 0.051213596129199464 4.962036671230574e-06 5.304340030459974 -0.22214956984939527 SSS(ph)LIQLTSQNSSPNQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSSLIQLTSQNSSPNQQR 18 0 H7C419;O95639 H7C419 CPSF4 Cleavage and polyadenylation specificity factor subunit 4 1 S(0.001)S(0.007)S(0.992)LIQLTSQNSSPNQQR;S(0.002)S(0.002)S(0.996)LIQLTSQNSSPNQQR;S(0.008)S(0.008)S(0.984)LIQLTSQNSSPNQQR;S(0.012)S(0.012)S(0.976)LIQLTSQNSSPNQQR 243.99 2.4621e-53 33260900.0 60569.5 58583.2 50206.6 58052.8 71965.7 58493.9 60777.5 75475.6 64524.8 45904.2 True False 70822.72004784473 64398.95293311909 51403.71575359078 54800.28982571702 57864.53769510003 55426.37691137418 55020.215209005066 73494.4454730084 65468.35313107146 54226.268082552764 1.3060592689142083 1.1875969933073705 0.9479486155184975 1.0105856767109693 1.067094228336135 1.0221315032595346 1.0146413750111591 1.35532921721853 1.2073180664286913 1.0 15.726704265298897 -7.73608016173615 24.969259984279297 1.2109929823443264 1.0732126894532634 0.12501402059176026 0.12583975153609223 357.61984667435013 352121.0007768997 0.06086720711523859 0.03512461749290581 1.8361993878188768e-08 7.73608016173615 -0.13778029289106297 SSS(ph)LIQLTSQNSSPNQQR ddPTM_PC-9_Lapatinib_30min_R1 4 SSSLIQLTSQNSSPNQQR 18 0 H7C419;O95639 H7C419 CPSF4 Cleavage and polyadenylation specificity factor subunit 4 1 SS(0.004)S(0.996)LIQLTSQNSSPNQQR;S(0.009)S(0.03)S(0.961)LIQLTSQNSSPNQQR;SS(0.004)S(0.996)LIQLTSQNSSPNQQR;S(0.001)S(0.001)S(0.997)LIQLTSQNSSPNQQR 371.87 3.476899999999998e-304 49469700.0 89821.0 80641.0 92814.0 59984.5 94176.0 88055.0 94776.0 90816.0 96063.0 89679.0 True False 88540.13606884601 80454.2807190684 85183.19119240064 64395.96023242605 88636.75283713987 84289.09291623048 99683.03753747049 95035.64290010762 85243.3733517642 105179.89566024372 0.8417971468126558 0.764920712404536 0.8098809250349779 0.6122459033467806 0.84271573270483 0.8013802674657946 0.9477385094530859 0.9035533102932097 0.8104531081407489 1.0 16.682499445197458 -6.970190235036368 2.139622411072251 0.9064121686886187 0.7640529332636349 0.43217731434209206 0.07595860161193264 0.3168980659889569 2.9278452976996405 0.03218015769231368 0.025719375283047234 1.0710500478911745e-07 6.970190235036368 -0.14235923542498385 SSS(ph)LPAYGR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSLPAYGR 9 0 Q08495-3;Q08495-4;Q08495-2;Q08495 Q08495-3 DMTN Dematin 1 SS(0.004)S(0.996)LPAYGR;SS(0.014)S(0.986)LPAYGR 94.40899999999999 0.005756600000000001 6880800.0 73615.0 65305.0 66450.0 56775.0 61247.0 61748.0 60727.0 60900.0 54073.0 51765.0 True False 72565.23660066219 65153.790284827206 60986.7375044178 60950.42289584788 57644.571876234935 59107.18198161836 63871.146920506944 63729.63632638045 47982.72932606676 60712.51127747315 1.1952270639739933 1.073152615727855 1.004516799275381 1.0039186588294364 0.949467756535109 0.9735585094064387 1.0520261075776942 1.0496952767300005 0.7903268752427695 1.0 15.889706228782027 -4.2449142383434495 0.9440895331396458 0.9756818644184998 1.6012601262407644 0.5010989804720748 0.0688618913453341 4.267939632479537 1.4901069688198212 0.02264135947501277 3.4812272056750775 5.689652753220275e-05 4.2449142383434495 0.6255782618222646 SSS(ph)LSDLTHR ddPTM_PC-9_AZD4547_30min_R2 2 SSSLSDLTHR 10 0 Q5T9C2-3;Q5T9C2-2;Q5T9C2 Q5T9C2-3 FAM102A Protein FAM102A 1 S(0.277)S(0.277)S(0.445)LSDLTHR;S(0.076)S(0.338)S(0.586)LSDLTHR 167.2 0.00023490000000000002 11423100.0 23994.0 25093.0 61507.0 71421.0 58316.0 47740.0 37170.0 54117.0 45403.0 46943.0 True False 31623.592893796234 33203.82152964024 60691.37699204013 54955.99189345033 50219.830007432254 44754.810253118645 40478.05799216874 45754.46113494595 47802.90988793843 45299.539858337186 0.6980996494156673 0.732983638100448 1.339779105523743 1.2131688768872984 1.1086167798719817 0.9879749417560963 0.8935644405826989 1.0100425142955407 1.055262592896747 1.0 15.467208775351498 -5.1407831912931075 8.41307716120064 1.0725592391607515 0.7078790975551505 0.5956383015403699 0.11889728184442419 0.21735335126946026 14.015588607195498 0.03391227277521121 0.09055784876860455 7.231307151821292e-06 5.1407831912931075 -0.3646801416056009 SSS(ph)LSDLTHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSLSDLTHR 10 0 Q5T9C2-3;Q5T9C2-2;Q5T9C2 Q5T9C2-3 FAM102A Protein FAM102A 1 S(0.311)S(0.311)S(0.376)LS(0.001)DLTHR;S(0.279)S(0.279)S(0.442)LSDLTHR 144.1 7.4682e-05 6035400.0 15199.0 22098.0 32513.0 23297.0 41358.0 28474.0 26062.0 27083.0 31775.0 23362.0 True False 17771.890506066422 24291.743399405746 33288.23322623912 21991.74461989308 33254.19679088716 26980.77331438779 23593.218687459834 26372.09994681047 32239.649262605923 27597.34566650976 0.6439710079666526 0.8802202825210301 1.2062114099123464 0.7968789783497459 1.204978087122421 0.9776582733871323 0.8549089819203498 0.9556027693929217 1.168215583201168 1.0 14.752241893729911 -4.877279686477853 3.6671514257099482 1.0119533331929405 0.6368458432517503 0.42827060808537865 0.13292055616439596 0.2268567714879546 5.1658437941678335 0.032383705686997805 0.19500943399003517 1.3265398883592014e-05 4.877279686477853 -0.37510748994119014 SSS(ph)LSDLTHR ddPTM_PC-9_Lapatinib_30min_R1 3 SSSLSDLTHR 10 0 Q5T9C2-3;Q5T9C2-2;Q5T9C2 Q5T9C2-3 FAM102A Protein FAM102A 1 S(0.265)S(0.265)S(0.47)LSDLTHR;S(0.287)S(0.287)S(0.426)LSDLTHR;S(0.26)S(0.26)S(0.479)LSDLTHR 161.93 7.2403e-05 16818200.0 43619.8 39631.0 61778.0 54832.0 62331.0 76970.0 61371.0 67957.0 86869.0 59615.0 True False 42997.77365310835 39539.2368544214 56698.85130997626 58864.5281941899 58664.813127461 73678.17252583345 64548.490089390776 71114.53030922567 77084.89844887641 69919.37331800562 0.6149622288167101 0.5654975864069889 0.8109176129497029 0.84189153021243 0.8390351678445844 1.0537590517399542 0.9231846200310304 1.017093359601269 1.1024826852820995 1.0 16.09340463368062 -5.508344695535018 0.5587682524525666 1.0406321454647596 0.4408245818980761 0.865465538098275 0.0626461467812357 0.6539072537481344 0.2712659282313598 0.039097384641774965 0.23183724443560974 3.1020965053358624e-06 5.508344695535018 -0.5998075635666835 SSS(ph)LVDIR ddPTM_PC-9_AZD4547_30min_R2 1 SSSLVDIR 8 0 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 1 S(0.012)S(0.045)S(0.943)LVDIR 78.098 0.022608 3339400.0 23978.0 29999.0 37109.0 27051.0 25574.0 31912.0 34864.0 46051.0 34624.0 25184.0 True False 31602.505226616922 39695.59008758128 36616.91041341014 20814.809883783822 22023.49153937294 29916.53759525602 37966.828459482684 38934.876096705215 36454.15395370306 24302.31582541302 1.3003906892515185 1.633407711954408 1.5067251481901862 0.8564949132138963 0.9062301591991859 1.2310159167618169 1.5622720374566375 1.602105592586813 1.5000279897433815 1.0 14.568806177769252 -7.245575464656153 22.767803030146474 1.466276850357829 1.236620476276216 0.08146699017759051 0.2709918250457526 562.2550046811137 806945.8061857112 0.11357492907638256 0.08756784563201989 5.6809966783015884e-08 7.245575464656153 -0.22965637408161288 SSS(ph)LVDIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSLVDIR 8 0 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 1 S(0.022)S(0.075)S(0.903)LVDIR;S(0.009)S(0.035)S(0.956)LVDIR 139.38 0.0027427 6335100.0 63877.0 134385.0 119032.0 74209.0 91763.0 67143.0 84649.0 47563.0 58704.0 56699.0 True False 74690.11447174191 147725.85468047485 121870.17431137357 70051.31031882415 73782.69887620716 63621.90288150374 76630.43391431165 46314.52164716414 59562.43494294314 66978.0798709629 1.1151426648186493 2.2055850953786247 1.8195531216505971 1.0458841228918776 1.1015947160377506 0.9498914122960075 1.1441121343272989 0.6914877484751983 0.8892825094074595 1.0 16.03140139697439 -5.791660613754509 5.99408126952116 0.9689026531833266 1.764656434656957 0.6014047505757569 0.2749320810200877 0.10603698996131135 11.028759682561605 0.07575773412844325 0.11731026011771836 1.6156206157453597e-06 5.791660613754509 0.7957537814736305 SSS(ph)LVDIR ddPTM_PC-9_Lapatinib_30min_R1 4 SSSLVDIR 8 0 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 1 S(0.011)S(0.004)S(0.986)LVDIR;S(0.209)S(0.368)S(0.423)LVDIR;S(0.006)S(0.02)S(0.974)LVDIR;S(0.088)S(0.304)S(0.609)LVDIR 145.46 1.4587e-12 7106600.0 118039.0 129291.0 115682.0 87523.0 111955.0 111874.0 101143.0 108816.0 112770.0 80888.0 True False 116355.74221429844 128991.63463311539 106171.07250543364 93959.7333881691 105370.0270119987 107089.4098110315 106379.68964350015 113871.98861233862 100068.65507925478 94869.38302351517 1.2264835978268929 1.3596761201782284 1.1191289446787815 0.9904115573817889 1.1106852775239484 1.1288089623655226 1.1213279379832368 1.2003028267203266 1.0548045311357288 1.0 16.5336549442777 -5.338197004292517 6.443785619549346 1.0964508458735482 1.292214603096357 0.597604132824323 0.06640866389246414 0.1469695358111119 10.064596632248234 0.017378589046650728 0.03680320781715019 4.589897590634081e-06 5.338197004292517 0.1957637572228088 SSS(ph)LVDIREEETEGGSR ddPTM_PC-9_AZD4547_30min_R2 2 SSSLVDIREEETEGGSR 17 1 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 1 S(0.001)S(0.003)S(0.996)LVDIREEETEGGSR;S(0.192)S(0.192)S(0.614)LVDIREEET(0.001)EGGSR 213.71 1.5387e-21 20990700.0 46044.0 35558.0 47982.0 72425.0 60225.0 50231.0 38667.0 60746.0 48000.0 53909.0 True False 60685.03422530442 47051.42812541137 47345.72732911816 55728.53520509562 51863.79830917087 47090.04762933396 42108.28809209545 51359.101504211714 50537.18200605782 52021.662318622526 1.1665339306848834 0.9044583742293846 0.9101156175889733 1.071256332867051 0.9969654178198926 0.9052007477369064 0.809437573028528 0.9872637515819322 0.9714641892165506 1.0 15.666824879955227 -6.744157563359887 17.787863224007758 0.9260502567812722 1.0018800369608292 0.15171410185812018 0.08670128147999498 17.084900390657076 17582.71862651579 0.029199556340317873 0.028997184213868408 1.8023637191830807e-07 6.744157563359887 0.075829780179557 SSS(ph)LVDIREEETEGGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSLVDIREEETEGGSR 17 1 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 1 S(0.184)S(0.184)S(0.631)LVDIREEET(0.001)EGGSR 64.5 0.010736 13453000.0 44831.0 50820.0 43352.0 57768.0 66652.0 56338.0 57614.0 45080.0 41707.0 33369.0 True False 52420.00284738889 55865.0737423206 44385.676093375565 54531.44624638292 53592.01906538538 53383.53610261919 52156.38483076171 43896.697766208184 42316.88597310793 39418.53555114134 1.3298313119567704 1.417228543912841 1.12601027594721 1.3833960466551118 1.35956392889978 1.3542749713103814 1.323143645534329 1.1136054942796367 1.07352760272401 1.0 15.266586558966077 -7.8516286782605755 2.933321586856809 1.0458483204239202 1.3295820916243368 0.7267862414386337 0.07537417262409515 0.14207829755950901 2.407153459028296 0.049578916977806343 0.020952505875042802 1.4072502086994449e-08 7.8516286782605755 0.28373377120041665 SSS(ph)LVDIREEETEGGSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSLVDIREEETEGGSR 17 1 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 1 S(0.163)S(0.163)S(0.673)LVDIREEET(0.001)EGGS(0.001)R 66.26100000000001 0.009612200000000001 14008000.0 56248.0 56429.0 77049.0 56400.0 56832.0 63150.0 38983.0 51221.0 59683.0 35827.0 True False 55445.89320538011 56298.3421174874 70714.32863774095 60547.844144884606 53489.25349601098 60449.22170983998 41001.34899471605 53600.91465145374 52960.87205014777 42019.64921352327 1.3195229908662789 1.339809902538853 1.6828871721038265 1.4409412091283802 1.2729581159567707 1.438594153955609 0.9757660942471766 1.2756154716827872 1.2603834882349105 1.0 15.358776497771194 -7.238110729364479 24.687969186602597 1.150909214785397 1.419124437879025 0.509965753400812 0.13747241620002673 616.8282361905826 652770.5337594687 0.05437203799132949 0.04208896625718348 5.779486726383653e-08 7.238110729364479 0.2682152230936281 SSS(ph)MAAGLER ddPTM_PC-9_AZD4547_30min_R2 3 SSSMAAGLER 10 0 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L0Y9;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 S(0.01)S(0.025)S(0.965)MAAGLER;SS(0.001)S(0.999)MAAGLER;SS(0.002)S(0.998)MAAGLER 110.08 0.0017916 133935500.0 167056.0 161932.0 266239.0 319403.0 302250.0 298590.0 232964.0 330959.0 263718.0 251507.0 True False 220176.33301933933 214273.35224714887 262708.4969025275 245769.57307715793 260287.80471476755 279919.12009800406 253697.34468893148 279816.8912312324 277657.59508903255 242701.81648277235 0.9071886490596912 0.8828667018335176 1.0824331713280575 1.012640023213849 1.0724592361394358 1.1533457975493706 1.0453046803089734 1.152924585758486 1.144027676071149 1.0 17.888825380704517 -5.248369457283391 1.0035618655588996 1.1020144978092308 0.8413054015138417 0.6155994278348125 0.05672197089952878 0.6304794473864318 0.8351750504138349 0.019281802187159084 0.1506098250073503 5.644565834325694e-06 5.248369457283391 -0.2607090962953891 SSS(ph)MAAGLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSMAAGLER 10 0 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L0Y9;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 S(0.027)S(0.056)S(0.917)MAAGLER 89.266 0.008329600000000001 99213000.0 63456.0 69716.0 76039.0 88897.0 100720.0 85099.0 75616.0 72921.0 72710.0 62050.0 True False 74197.84748687095 76636.94374300698 77852.05813951323 83916.38929796267 80984.63902456987 80636.25863177242 68453.10506756818 71006.90101618608 73773.24619619444 73299.17381247038 1.0122603520293385 1.045536255825693 1.0621137195719423 1.1448476829037053 1.1048506389957693 1.1000977833402779 0.9338864479250413 0.968727167346403 1.006467636114657 1.0 16.16150931674388 -7.254439534261594 24.970437277555725 0.9746642425633434 1.0802939841597428 0.6247070660521241 0.03831583743740081 378.26406084049034 1349378.4676129983 0.01633496892660073 0.012377787948490966 5.5662212597508e-08 7.254439534261594 0.10562974159639937 SSS(ph)MAAGLER ddPTM_PC-9_Lapatinib_30min_R1 6 SSSMAAGLER 10 0 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L0Y9;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 S(0.024)S(0.235)S(0.741)MAAGLER;S(0.004)S(0.033)S(0.963)MAAGLER;S(0.008)S(0.021)S(0.97)MAAGLER;SS(0.002)S(0.998)MAAGLER;SS(0.003)S(0.996)MAAGLER;SS(0.005)S(0.995)MAAGLER 148.28 0.00015091 357298000.0 1758585.0 1391220.0 2161440.0 1392068.0 1570350.0 1831970.0 1069661.0 1226798.0 1849229.0 1005073.0 True False 1733507.2554150051 1387998.7155663006 1983734.7465996784 1494445.3245227148 1477985.100426888 1753620.9136306525 1125042.8126885304 1283799.5137262857 1640949.3567753427 1178798.5288744068 1.4705712748643063 1.1774689920012469 1.6828446066130374 1.267769926680947 1.2538063665876509 1.4876341212481181 0.9543978764232037 1.0890745808379492 1.3920524301487103 1.0 20.16888573443476 -7.253967746793762 24.969444814363715 1.1163041008434782 1.3819170809268972 0.3886998471864611 0.1724392307112415 630.5301223439637 2107172.6627410487 0.06553169323885724 0.049748121033807484 5.572271302871033e-08 7.253967746793762 0.26561298008341905 SSS(ph)MADGDNSYCLEAIIR ddPTM_PC-9_AZD4547_30min_R2 2 SSSMADGDNSYCLEAIIR 18 0 A0A0A0MR36;Q9ULV0-2;Q9ULV0;Q9ULV0-3 A0A0A0MR36 MYO5B Unconventional myosin-Vb 1 S(0.007)S(0.009)S(0.984)MADGDNSYCLEAIIR;S(0.135)S(0.043)S(0.821)MADGDNSYCLEAIIR 186.72 9.901700000000001e-11 10906500.0 30426.3 29284.9 34883.0 43497.0 37487.0 36700.0 37203.0 41390.0 37179.0 37777.0 True False 40101.23049364479 38750.67122756792 34420.4286278527 33469.43867195091 32282.57712272126 34405.14319835471 40513.994928239284 34994.12654758047 39144.206037567186 36454.43872842389 1.1000369747121483 1.06298910583291 0.9442040483540554 0.9181169657086081 0.8855595710365501 0.9437847460679369 1.1113597230246235 0.9599414438465952 1.0737843566645302 1.0 15.153806868768516 -9.772747788085596 13.417807348807134 0.9999963706792114 0.9948613647702328 0.0 0.0772884044538615 0.0 0.0 0.08003527119358243 0.019411404523887937 1.6875327576283182e-10 9.772747788085596 -0.00513500590897864 SSS(ph)MADGDNSYCLEAIIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSMADGDNSYCLEAIIR 18 0 A0A0A0MR36;Q9ULV0-2;Q9ULV0;Q9ULV0-3 A0A0A0MR36 MYO5B Unconventional myosin-Vb 1 S(0.121)S(0.032)S(0.847)MADGDNSYCLEAIIR;S(0.043)S(0.043)S(0.914)MADGDNSYCLEAIIR 92.427 0.0010023 4356000.0 15219.2 18883.8 18644.8 21227.4 26710.8 26411.1 33747.3 30949.4 27511.5 25776.1 True False 17795.50996709823 20758.45886531352 19089.362742797755 20038.097598159344 21477.010485082166 25026.055421915687 30550.511434706215 30137.011043599923 27913.803640855487 30449.102886504657 0.584434623030729 0.6817428724481034 0.6269269348903658 0.6580849909716199 0.7053413220460097 0.8218979559167072 1.0033304281107902 0.9897503764210059 0.9167364879320355 1.0 14.894112102582309 -6.902557959126951 1.853247619330598 0.9792427086217159 0.6414649058683992 0.9504486188938762 0.03526312301174452 0.06779599810400333 0.47594425230628 0.015163690110878049 0.012512851633679819 1.2515322376228677e-07 6.902557959126951 -0.3377778027533167 SSS(ph)MADGDNSYCLEAIIR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSMADGDNSYCLEAIIR 18 0 A0A0A0MR36;Q9ULV0-2;Q9ULV0;Q9ULV0-3 A0A0A0MR36 MYO5B Unconventional myosin-Vb 1 S(0.008)S(0.008)S(0.983)MADGDNS(0.001)YCLEAIIR 103.61 0.0003449 2343900.0 9639.0 13684.0 12380.0 15175.0 19748.0 19703.0 23831.0 22919.0 30691.0 21278.0 True False 9501.546092423892 13652.315538742452 11362.164188181978 16291.020122316018 18586.461466061817 18860.3486199363 25064.852574021475 23983.900409923044 27234.25638944231 24955.873948847184 0.3807338549593375 0.5470582022783902 0.45529017382726616 0.6527930120062403 0.7447730143275709 0.7557478715670279 1.004366852685571 0.9610523141398926 1.091296439678498 1.0 14.607091807115177 -6.5604051933578065 0.6596324888901222 1.0576750310626806 0.4139781046345066 0.9338305860625097 0.06094159885972318 0.1744889232766489 0.1684580856641759 0.04210992173170282 0.05533495975258734 2.7516602278510623e-07 6.5604051933578065 -0.643696926428174 down SSS(ph)MELHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSMELHR 8 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5;X6R5W5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 S(0.298)S(0.298)S(0.405)MELHR 72.243 0.023029 3140600.0 10167.0 12624.0 20397.0 15372.0 22377.0 14288.0 17423.0 15921.0 13193.0 17444.0 True False 11888.072292596702 13877.22729089049 20883.34183605325 14510.756676696414 17992.387484638566 13538.712127413522 15772.56730840352 15503.0906196939 13385.922666296146 20606.45911337198 0.5769099983258295 0.6734406534641003 1.0134366958028995 0.7041848673205611 0.8731430948737289 0.657013029406297 0.7654186108164677 0.7523413185350998 0.6495983901285461 1.0 14.330809001920404 -5.008513752441629 24.063022305193932 0.7894795436411598 0.601042463678332 0.2624562060065063 0.12182163469693429 320.975210240751 907229.6665844192 0.029180569956536423 0.09481837300542488 9.805872623902323e-06 5.008513752441629 -0.18843707996282777 SSS(ph)MSSIDLVSASDDVHR ddPTM_PC-9_AZD4547_30min_R2 2 SSSMSSIDLVSASDDVHR 18 0 A0A2U3TZL3;Q9Y5P4;Q9Y5P4-3;A0A0A0MRE4;A0A2R8YFA1 A0A2U3TZL3 COL4A3BP Collagen type IV alpha-3-binding protein 1 S(0.094)S(0.094)S(0.609)MS(0.177)S(0.026)IDLVSASDDVHR;S(0.102)S(0.102)S(0.456)MS(0.17)S(0.17)IDLVSASDDVHR 152.64 2.3364000000000002e-05 9765500.0 5971.3 6717.1 15679.6 30877.0 17369.8 21179.0 13738.599999999999 19202.0 16947.6 11385.2 True False 7870.049189244204 8888.271214950242 15471.67825913136 23758.784694894563 14958.30309457263 19854.673781960606 14961.30878480521 16234.7721180633 17843.415536788874 10986.60761338517 0.716331142986848 0.8090096167739268 1.4082307117514559 2.1625223664080653 1.3615033521674769 1.8071705553378754 1.3617769298120372 1.4776874436003524 1.624106017498062 1.0 13.423458366849546 -5.292440746810103 4.007130984674541 1.5714040291675249 0.7432179991776622 0.527504824686033 0.28966402208916847 0.14418500346781182 5.233004147610188 0.0733400646409061 0.18027744363723275 5.099871731894401e-06 5.292440746810103 -0.8281860299898627 SSS(ph)MSSIDLVSASDDVHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSSMSSIDLVSASDDVHR 18 0 A0A2U3TZL3;Q9Y5P4;Q9Y5P4-3;A0A0A0MRE4;A0A2R8YFA1 A0A2U3TZL3 COL4A3BP Collagen type IV alpha-3-binding protein 1 S(0.128)S(0.128)S(0.571)MS(0.157)S(0.015)IDLVSASDDVHR;S(0.088)S(0.088)S(0.336)MS(0.336)S(0.151)IDLVSASDDVHR;S(0.09)S(0.09)S(0.328)MS(0.246)S(0.246)IDLVSASDDVHR 87.49600000000001 0.0011347000000000002 17952900.0 19950.8 17236.8 28614.1 32572.6 39432.0 41748.0 34980.8 42864.9 33565.3 29555.4 True False 23328.076393738396 18947.955589957317 29296.36866357854 30747.66282379401 31705.582664980448 39558.661386846295 31667.165384939566 41739.741794115755 34056.129013191065 34913.56005958235 0.6681666479708015 0.542710498660731 0.8391114688270778 0.8806796777905503 0.9081165773662935 1.1330457655803867 0.9070162232352532 1.1955166337344019 0.9754413172152018 1.0 15.091499852407987 -5.685252660567675 0.9584846988323167 1.0456787087012536 0.5648065035667885 0.7444030172414798 0.09358872484818181 0.3308290398371407 0.5449533638593959 0.03515660716337556 0.12339034765643234 2.0641789239789066e-06 5.685252660567675 -0.48087220513446505 SSS(ph)MSSIDLVSASDDVHR ddPTM_PC-9_Lapatinib_30min_R1 3 SSSMSSIDLVSASDDVHR 18 0 A0A2U3TZL3;Q9Y5P4;Q9Y5P4-3;A0A0A0MRE4;A0A2R8YFA1 A0A2U3TZL3 COL4A3BP Collagen type IV alpha-3-binding protein 1 S(0.11)S(0.11)S(0.609)MS(0.163)S(0.008)IDLVSASDDVHR;S(0.076)S(0.076)S(0.395)MS(0.395)S(0.058)IDLVSASDDVHR;S(0.1)S(0.1)S(0.446)MS(0.354)S(0.001)IDLVSASDDVHR 93.804 0.00069272 10682300.0 19867.3 13697.8 26806.4 19191.699999999997 22750.3 19527.1 16595.300000000003 13063.400000000001 28381.699999999997 14473.3 True False 19583.98865878339 13666.083585690325 24602.48126769638 20603.12163963441 21412.17208281073 18691.971452893384 17454.52343257348 13670.373254286334 25185.05407344939 16974.990620539997 1.1536965820226412 0.8050716428175316 1.449336957979052 1.2137339042004724 1.2613952232115921 1.1011476748785838 1.0282493712516836 0.8053243480290926 1.4836564353075454 1.0 14.051123156864572 -6.987487951418047 22.74522961716009 1.0633151050600802 1.1740194771901 0.04263687750220291 0.21680209163426764 264.8341755509541 481425.5627373016 0.07611525884644024 0.06706146704563053 1.0292290805825728e-07 6.987487951418047 0.11070437213001982 SSS(ph)MSSLTGAYASGIPSSSR ddPTM_PC-9_AZD4547_30min_R2 2 SSSMSSLTGAYASGIPSSSR 20 0 Q96HA1;Q96HA1-2;Q96HA1-3 Q96HA1 POM121 Nuclear envelope pore membrane protein POM 121 1 S(0.001)S(0.019)S(0.98)MSSLTGAYASGIPSSSR;SS(0.014)S(0.985)MS(0.001)SLTGAYASGIPSSSR 209.19 1.9622e-21 29163000.0 27432.0 27252.4 42152.0 47576.0 43013.0 40431.0 34500.0 48767.0 34371.0 35904.0 True False 36154.80537895383 36061.20535027169 41593.03693837249 36608.0882418727 37041.387408424525 37902.84317854714 37570.433164644084 41231.180704176295 36187.7808902128 34647.01188832708 1.0435187165775397 1.0408171840764446 1.2004797721787257 1.0566016013117232 1.069107706252271 1.0939714888173946 1.084377298848734 1.1900356901504539 1.0444704728607441 1.0 15.080443312870559 SSS(ph)MSSLTGAYASGIPSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSMSSLTGAYASGIPSSSR 20 0 Q96HA1;Q96HA1-2;Q96HA1-3 Q96HA1 POM121 Nuclear envelope pore membrane protein POM 121 1 S(0.091)S(0.022)S(0.769)MS(0.091)S(0.028)LTGAYASGIPSSSR;S(0.037)S(0.019)S(0.942)MS(0.002)SLTGAYASGIPSSSR 159.18 9.2918e-06 22894300.0 40574.0 48779.0 56270.0 57131.0 94470.0 83640.0 85211.0 107224.0 81892.0 75208.0 True False 47442.376826971464 53621.456750819656 57611.69020516339 53930.13529120107 75959.28165856944 79253.77116019501 77139.19720578386 104409.4836132191 83089.51557555704 88842.61505379938 0.5340047318310288 0.6035555878037667 0.6484690952678076 0.6070300301104737 0.8549870083469703 0.8920693195737455 0.8682679720657882 1.1752184866462234 0.9352439201079515 1.0 16.43896423832384 -6.536926063675848 0.8587510378018045 1.0307049275136166 0.559750169939742 0.8435203130248503 0.07745308100671934 0.21641056934826458 0.3516322646595834 0.0438462553045274 0.05258131979907293 2.9045170909520477e-07 6.536926063675848 -0.4709547575738746 SSS(ph)MSSLTGAYASGIPSSSR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSMSSLTGAYASGIPSSSR 20 0 Q96HA1;Q96HA1-2;Q96HA1-3 Q96HA1 POM121 Nuclear envelope pore membrane protein POM 121 1 SS(0.011)S(0.564)MS(0.4)S(0.024)LTGAYASGIPSSSR;SS(0.005)S(0.976)MS(0.018)SLTGAYASGIPSSSR 192.22 1.5398e-12 15448300.0 29775.0 31362.0 33563.0 25957.0 33437.0 44072.0 38614.0 37442.0 60753.0 36580.0 True False 29350.40303993373 31289.383215875554 30803.579696926623 27865.96437001363 31470.301399671313 42187.143296849856 40613.243980246916 39181.692008741156 53910.357382548296 42902.804260213845 0.6841138602949549 0.7293085791338805 0.7179852279607861 0.6495138220103549 0.7335255105656455 0.983319016653938 0.9466337849134453 0.9132664562226884 1.2565695485910782 1.0 15.388784329374072 -6.763756850302756 3.4472125858011786 1.0161732542986472 0.6972320504674149 0.7658957059203898 0.08801187960872701 0.11821063769114483 2.9604322868464163 0.03165558505391817 0.0294670587493861 1.7228328724006072e-07 6.763756850302756 -0.31894120383123237 SSS(ph)MSSLTGAYTSGIPSSSR ddPTM_PC-9_AZD4547_30min_R2 1 SSSMSSLTGAYTSGIPSSSR 20 0 A8CG34-2;A8CG34 A8CG34-2 POM121C Nuclear envelope pore membrane protein POM 121C 1 SS(0.005)S(0.993)MS(0.002)SLTGAYTSGIPSSSR 196.01 1.6133e-15 12653000.0 33563.0 31103.0 45049.0 58740.0 47575.0 43499.0 31154.0 55287.0 36981.0 43121.0 True False 44235.3358462317 41156.43649768464 44451.62082550631 45198.4005239533 40970.032454276545 40779.000653548566 33926.64564670501 46743.66451887127 38935.74016179216 41611.346915010894 1.0630594567529903 0.9890676353674543 1.0682571971605854 1.0862037370784652 0.9845879908178843 0.9799971324369203 0.8153219773442685 1.123339376981545 0.9357000685730378 1.0 15.34468936719088 -6.409043220292222 5.617391129528442 0.970214363201973 1.0480788669434586 0.21207212124511932 0.0743032390527615 0.39090077507637105 16.741176263191438 0.023163080446202973 0.026224199610413133 3.899031822046196e-07 6.409043220292222 0.07786450374148568 SSS(ph)MSSLTGAYTSGIPSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSMSSLTGAYTSGIPSSSR 20 0 A8CG34-2;A8CG34 A8CG34-2 POM121C Nuclear envelope pore membrane protein POM 121C 1 S(0.006)S(0.004)S(0.847)MS(0.114)S(0.025)LT(0.006)GAYTSGIPSSSR 124.63 9.6016e-06 11243000.0 43827.0 46707.0 51520.0 61355.0 88844.0 82950.0 79131.0 82773.0 70236.0 70170.0 True False 51246.0454772928 51343.76228419064 52748.43219068805 57917.478265593825 71435.65597199024 78599.95597487061 71635.13882117195 80600.29645524271 71263.06862654263 82891.26553458582 0.6182321520463544 0.6194110073366874 0.6363569412350101 0.698716298901579 0.861799557664905 0.948229653244651 0.8642061182101589 0.9723617553119971 0.8597174644029123 1.0 16.338932468799747 -6.224365455285681 1.9641164839912917 0.9248074945970973 0.6218794362756778 0.9180672927130549 0.0410084726400894 0.08189768489803774 0.6209334830376276 0.013040667195725506 0.01749565426861255 5.965330975539951e-07 6.224365455285681 -0.30292805832141956 SSS(ph)MSSLTGAYTSGIPSSSR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSMSSLTGAYTSGIPSSSR 20 0 A8CG34-2;A8CG34 A8CG34-2 POM121C Nuclear envelope pore membrane protein POM 121C 1 S(0.005)S(0.005)S(0.989)MS(0.001)SLTGAYTSGIPSSSR;S(0.043)S(0.043)S(0.91)MS(0.004)S(0.001)LTGAYTSGIPSSSR 169.58 2.1397e-08 14291900.0 43971.0 39451.0 34089.0 29948.7 40627.0 49525.0 46712.0 43339.0 77235.0 36543.0 True False 43343.96547670617 39359.6536333622 31286.334007345333 32151.22730393448 38237.39973575517 47406.93119841372 49130.518796428616 45352.68815679806 68535.9809793938 42859.40885951324 1.0113057232959333 0.9183433621862886 0.729975863873841 0.7501556404877495 0.8921588223741412 1.1061032445362597 1.1463181621909704 1.0581734411096853 1.5990883402998988 1.0 15.387324331259428 -6.91857119660447 1.7945603225002185 1.2167586103008476 0.8432849998498163 0.48826456929787965 0.1668852668531678 0.30215811734552983 1.9864498179117585 0.07426180971682207 0.06032341378685637 1.2062263277784803e-07 6.91857119660447 -0.37347361045103133 SSS(ph)MSYVDGFIGTWPK ddPTM_PC-9_AZD4547_30min_R2 2 SSSMSYVDGFIGTWPK 16 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 S(0.038)S(0.038)S(0.696)MS(0.19)Y(0.038)VDGFIGTWPK;S(0.039)S(0.039)S(0.85)MS(0.072)YVDGFIGTWPK 113.11 0.00023945 32737000.0 94146.0 83127.0 120927.0 147610.0 143870.0 137662.0 119998.0 151887.0 140194.0 130618.0 True False 124082.4696415494 109996.17711291621 119323.42896770172 113580.79505176625 123896.13387696797 129053.97337798103 130677.58953307169 128416.35416603916 147604.36862827663 126045.10357702518 0.9844291140252313 0.8726731462892441 0.9466724655018758 0.9011123147862536 0.9829507879396204 1.0238713739412906 1.0367526054133125 1.0188127148276327 1.1710440504186403 1.0 16.943580549933152 -6.768014476657308 1.2628090760026902 1.0643608694743094 0.9215722591967097 0.5716987074830935 0.050911617714895656 0.30523556533990387 1.0233525856396646 0.024031738847221727 0.021538251248883727 1.7060255198521798e-07 6.768014476657308 -0.1427886102775997 SSS(ph)MSYVDGFIGTWPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSMSYVDGFIGTWPK 16 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 S(0.018)S(0.093)S(0.848)MS(0.04)YVDGFIGTWPK;S(0.107)S(0.107)S(0.74)MS(0.029)Y(0.016)VDGFIGTWPK 129.05 1.6518e-05 44739000.0 101515.0 105258.0 96122.0 118010.0 129045.0 121332.0 134374.0 125963.0 112912.0 104130.0 True False 118699.48448735655 115707.31861411194 98413.91302471519 111398.28229358206 103759.55860728332 114969.13632722125 121645.12193648743 122656.60471883071 114563.12439148249 123007.94470737374 0.9649741304899722 0.9406491498526423 0.8000614371602922 0.9056185969011176 0.843519163368831 0.93464805546279 0.9889208556883999 0.9971437618165327 0.9313473586118294 1.0 16.908391972275965 -7.007764732953867 5.178350037192269 0.9775026723670369 0.8891370601723209 0.441603134428047 0.0467814613493774 0.17692621547871035 14.51562403376374 0.018107600252224427 0.014902948803367873 9.822799219447311e-08 7.007764732953867 -0.08836561219471606 SSS(ph)PAELDLKDDLQQTQGK ddPTM_PC-9_AZD4547_30min_R2 3 SSSPAELDLKDDLQQTQGK 19 1 H7C1F9;Q2PPJ7-3;Q2PPJ7-2;Q2PPJ7 H7C1F9 RALGAPA2 Ral GTPase-activating protein subunit alpha-2 1 S(0.159)S(0.159)S(0.682)PAELDLKDDLQQTQGK;S(0.111)S(0.111)S(0.778)PAELDLKDDLQQTQGK;S(0.168)S(0.168)S(0.664)PAELDLKDDLQQTQGK 88.755 0.00051777 19993700.0 60117.9 73163.4 69277.5 93839.0 94205.0 84207.0 71994.0 88974.0 74744.0 82799.0 True False 79234.14166999902 96812.0382617335 68358.83508488559 72205.86834809757 81126.26184666586 78941.52297830672 78401.32652914149 75225.11271912098 78694.81524709967 79900.23221205432 0.9916634717620406 1.2116615381641873 0.855552395685935 0.903700356670604 1.0153445065260596 0.9880011708701522 0.9812402837712065 0.9414880362234038 0.9849134735709467 1.0 16.28591207557745 -5.263131413714131 24.999996254223195 0.9585891096201462 1.101662499551806 0.41988855057759955 0.06717777371059286 129.9545097048198 1920124.0262597064 0.017013687434211354 0.03861890410951269 5.455927445155559e-06 5.263131413714131 0.14307338993165986 SSS(ph)PAELDLKDDLQQTQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSPAELDLKDDLQQTQGK 19 1 H7C1F9;Q2PPJ7-3;Q2PPJ7-2;Q2PPJ7 H7C1F9 RALGAPA2 Ral GTPase-activating protein subunit alpha-2 1 S(0.167)S(0.167)S(0.666)PAELDLKDDLQQT(0.001)QGK 73.796 0.0021873 6511400.0 25181.0 28904.0 21523.0 29473.0 38385.0 30916.0 31914.0 25245.0 26043.0 30211.0 True False 29443.645952579674 31773.398100118713 22036.189946432034 27821.72336275522 30863.734799028072 29294.71053549246 28890.874882648823 24582.345499288498 26423.829606484516 35688.015149855586 0.8250289580113793 0.8903100373248773 0.6174675126621942 0.7795816955896973 0.864820715565992 0.8208556965828065 0.8095399747319859 0.6888123476765553 0.7404118580293598 1.0 15.1231520452096 SSS(ph)PAELDLKDDLQQTQGK ddPTM_PC-9_Lapatinib_30min_R1 3 SSSPAELDLKDDLQQTQGK 19 1 H7C1F9;Q2PPJ7-3;Q2PPJ7-2;Q2PPJ7 H7C1F9 RALGAPA2 Ral GTPase-activating protein subunit alpha-2 1 S(0.183)S(0.183)S(0.633)PAELDLKDDLQQTQGK;S(0.141)S(0.141)S(0.717)PAELDLKDDLQQTQGK;S(0.167)S(0.167)S(0.667)PAELDLKDDLQQTQGK 83.436 0.00072628 16066500.0 95442.0 88758.0 88663.0 88155.0 92114.0 94154.0 85799.0 92420.0 96504.0 64146.0 True False 94080.97957808097 88552.48630427537 81373.47038907728 94638.21277645932 86696.03562309197 90127.25290369407 90241.25240226884 96714.17059579755 85634.70328782841 75233.55063082778 1.2505189345606964 1.177034521988784 1.0816114580099798 1.2579256459774246 1.1523586869973848 1.1979662284709904 1.1994815032070478 1.2855191571427422 1.1382515190335658 1.0 16.199088559195758 -8.539162400771847 22.91849686563999 0.9999999969498622 1.1967936637315268 0.5510505917276739 0.054896418739295336 758.4263827473446 1067450.711244089 0.0524849867447818 0.01355156532308334 2.889599138995784e-09 8.539162400771847 0.19679366678166466 SSS(ph)PAGETEGDREPQAR ddPTM_PC-9_AZD4547_30min_R2 1 SSSPAGETEGDREPQAR 17 1 Q9BTC0 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 S(0.036)S(0.036)S(0.777)PAGET(0.15)EGDREPQAR 88.319 0.0012955 9607900.0 8718.0 21314.0 26284.0 20396.0 20602.0 26421.0 22652.0 24761.0 27049.0 18056.0 True False 11490.142654335072 28203.333682013 25935.456986339497 15694.017315058762 17741.76791640579 24768.89069328964 24667.984117261392 20934.756401175153 28478.75491837205 17423.864935818667 0.6594485607331875 1.6186611745385326 1.488501953032438 0.9007196378569364 1.0182452619874023 1.4215497413763591 1.4157584558952137 1.2014990060063575 1.6344683009925987 1.0 14.088777055453601 -6.778519641057267 24.947036948546824 1.3523177568105749 1.1702562146516213 0.0918971410332865 0.2990535117092673 679.8926635708325 993028.9690438296 0.10571438573726336 0.0934592009179045 1.6652535146493116e-07 6.778519641057267 -0.18206154215895354 SSS(ph)PAGETEGDREPQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSPAGETEGDREPQAR 17 1 Q9BTC0 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 S(0.17)S(0.17)S(0.659)PAGET(0.002)EGDREPQAR;S(0.067)S(0.067)S(0.866)PAGETEGDREPQAR 93.81200000000001 0.00085529 36396000.0 40631.0 70608.0 69251.0 53422.0 67170.0 56748.0 52764.0 43085.0 44412.0 41150.0 True False 47509.025801170115 77617.49560798462 70902.20647587984 50428.93853646081 54008.520683879535 53772.03498085543 47765.81194172092 41954.06440233094 45061.4414807507 48610.1692567792 0.9773474671566688 1.5967337039699783 1.4585879366382124 1.0374154072592119 1.1110539524885008 1.106189009480899 0.9826300272562716 0.863071761398568 0.9269961855659741 1.0 15.568970537035147 -6.305683830953337 1.0558774229179642 0.9459699020398645 1.3545388759855415 0.4337467093228501 0.16892388627817462 0.4648652761440685 1.0894217449674604 0.07743300200527564 0.11263911239518834 4.94670679221299e-07 6.305683830953337 0.4085689739456769 SSS(ph)PAGETEGDREPQAR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSPAGETEGDREPQAR 17 1 Q9BTC0 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 S(0.171)S(0.171)S(0.639)PAGET(0.019)EGDREPQAR;S(0.026)S(0.026)S(0.808)PAGET(0.139)EGDREPQAR 90.853 0.0044432 16033800.0 18871.7 30641.0 34494.0 30964.0 33082.0 31027.0 34269.0 39663.0 35985.0 31951.0 True False 18602.58609735408 30570.052647077442 31658.03647069056 33241.19585287599 31136.181801714465 29700.047537469603 36043.281140495215 41505.88777690029 31931.990361150878 37473.68777796865 0.4964172783734091 0.815773799157553 0.844807072585549 0.8870542992680587 0.8308811768459015 0.7925573728809983 0.9618290399933793 1.107600832424671 0.8521176391912029 1.0 15.193590339527443 -4.413324247358676 1.1253213470131453 0.9183067871913392 1.0982032594117798e-40 0.6685243963562402 0.08766240526395871 2.234899571648966 1.357792648823261 0.02891072253326232 2.9637607545994733 3.860786203704271e-05 4.413324247358676 -0.9183067871913392 SSS(ph)PAGETEGDREPQARPGEGTAPLPPPGQK ddPTM_PC-9_AZD4547_30min_R2 2 SSSPAGETEGDREPQARPGEGTAPLPPPGQK 31 2 Q9BTC0 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 S(0.116)S(0.116)S(0.384)PAGET(0.384)EGDREPQARPGEGTAPLPPPGQK;S(0.158)S(0.158)S(0.674)PAGET(0.009)EGDREPQARPGEGTAPLPPPGQK 67.899 0.0002355 32752000.0 24690.0 20919.6 25797.0 47751.0 40827.0 34549.0 23474.0 35389.0 27183.0 29945.0 True False 32540.906416096903 27681.45159492534 25454.91492453964 36742.74469559574 35158.875775317865 32388.645568391203 25563.140524836388 29920.44320831905 28619.837884805627 28896.63466454865 1.1261140542438033 0.957947245977604 0.8808954821223032 1.2715233148126055 1.2167117791903963 1.1208448992202773 0.8846407487096792 1.0354300269098964 0.9904211413212555 1.0 14.818613864127515 -7.23676933642067 24.7439499646187 0.980575460093312 1.0931449215001736 0.21077948182293782 0.11178410484313987 1290.0798590794923 1293946.510352923 0.047327239785983764 0.03664094377662981 5.79736525796179e-08 7.23676933642067 0.11256946140686164 SSS(ph)PAPADIAQTVQEDLR ddPTM_PC-9_AZD4547_30min_R2 37 SSSPAPADIAQTVQEDLR 18 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 1 S(0.005)S(0.023)S(0.973)PAPADIAQTVQEDLR;S(0.009)S(0.009)S(0.981)PAPADIAQTVQEDLR;S(0.001)S(0.032)S(0.967)PAPADIAQTVQEDLR;SS(0.005)S(0.995)PAPADIAQTVQEDLR;S(0.004)S(0.204)S(0.791)PAPADIAQTVQEDLR;S(0.009)S(0.03)S(0.961)PAPADIAQTVQEDLR;S(0.004)S(0.185)S(0.811)PAPADIAQTVQEDLR;S(0.236)S(0.236)S(0.527)PAPADIAQTVQEDLR;S(0.001)S(0.009)S(0.99)PAPADIAQTVQEDLR;SS(0.016)S(0.984)PAPADIAQTVQEDLR;SS(0.009)S(0.99)PAPADIAQTVQEDLR;S(0.178)S(0.178)S(0.644)PAPADIAQTVQEDLR;S(0.097)S(0.097)S(0.807)PAPADIAQTVQEDLR;S(0.208)S(0.019)S(0.773)PAPADIAQTVQEDLR;S(0.001)S(0.188)S(0.811)PAPADIAQTVQEDLR;S(0.003)S(0.003)S(0.993)PAPADIAQTVQEDLR;S(0.035)S(0.028)S(0.937)PAPADIAQTVQEDLR;S(0.025)S(0.025)S(0.95)PAPADIAQTVQEDLR;SS(0.078)S(0.921)PAPADIAQTVQEDLR;S(0.001)S(0.038)S(0.961)PAPADIAQTVQEDLR;S(0.063)S(0.063)S(0.875)PAPADIAQTVQEDLR;S(0.002)S(0.007)S(0.991)PAPADIAQTVQEDLR;S(0.002)S(0.002)S(0.996)PAPADIAQTVQEDLR;S(0.175)S(0.175)S(0.65)PAPADIAQTVQEDLR;S(0.148)S(0.004)S(0.849)PAPADIAQTVQEDLR;SS(0.001)S(0.999)PAPADIAQTVQEDLR;S(0.001)S(0.004)S(0.995)PAPADIAQTVQEDLR;SS(0.226)S(0.773)PAPADIAQTVQEDLR;S(0.022)S(0.022)S(0.956)PAPADIAQTVQEDLR;S(0.002)S(0.002)S(0.995)PAPADIAQTVQEDLR;S(0.016)S(0.023)S(0.961)PAPADIAQTVQEDLR;SS(0.026)S(0.974)PAPADIAQTVQEDLR;S(0.154)S(0.154)S(0.692)PAPADIAQTVQEDLR;S(0.01)S(0.029)S(0.48)PAPADIAQT(0.48)VQEDLR;SS(0.001)S(0.998)PAPADIAQTVQEDLR;S(0.191)S(0.191)S(0.618)PAPADIAQTVQEDLR;S(0.011)S(0.011)S(0.977)PAPADIAQTVQEDLR 362.14 3.6301999999999985e-275 18450933100.0 11861725.000000004 9936297.100000003 16888641.5 19826583.800000004 21097488.000000004 15724954.100000001 13585054.200000003 17312636.399999995 14133563.799999999 17541536.19999999 True False 15633506.810792958 13148010.822694857 16664687.07886768 15255871.22257616 18168465.96035119 14741670.234279435 14794097.706062838 14637366.249186914 14880635.128225613 16927412.356866043 0.9235615273737775 0.776728926164654 0.9844793006479932 0.9012524124154229 1.0733162031692196 0.8708755906392253 0.8739727841545789 0.8647137519072579 0.8790850494162965 1.0 24.01285811380407 SSS(ph)PAPADIAQTVQEDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 44 SSSPAPADIAQTVQEDLR 18 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 1 S(0.101)S(0.101)S(0.797)PAPADIAQTVQEDLR;S(0.002)S(0.228)S(0.77)PAPADIAQTVQEDLR;S(0.003)S(0.009)S(0.989)PAPADIAQTVQEDLR;SS(0.023)S(0.977)PAPADIAQTVQEDLR;S(0.041)S(0.041)S(0.919)PAPADIAQTVQEDLR;SS(0.011)S(0.988)PAPADIAQTVQEDLR;S(0.001)S(0.022)S(0.976)PAPADIAQTVQEDLR;S(0.112)S(0.112)S(0.776)PAPADIAQTVQEDLR;SS(0.007)S(0.993)PAPADIAQTVQEDLR;SS(0.004)S(0.996)PAPADIAQTVQEDLR;SS(0.022)S(0.978)PAPADIAQTVQEDLR;S(0.049)S(0.049)S(0.76)PAPADIAQT(0.142)VQEDLR;S(0.106)S(0.106)S(0.788)PAPADIAQTVQEDLR;S(0.006)S(0.006)S(0.989)PAPADIAQTVQEDLR;S(0.059)S(0.059)S(0.882)PAPADIAQTVQEDLR;S(0.003)S(0.096)S(0.901)PAPADIAQTVQEDLR;SS(0.023)S(0.977)PAPADIAQTVQEDLR;S(0.001)S(0.005)S(0.994)PAPADIAQTVQEDLR;S(0.185)S(0.185)S(0.63)PAPADIAQTVQEDLR;SS(0.01)S(0.99)PAPADIAQTVQEDLR;S(0.039)S(0.039)S(0.923)PAPADIAQTVQEDLR;SS(0.001)S(0.999)PAPADIAQTVQEDLR;S(0.03)S(0.03)S(0.94)PAPADIAQTVQEDLR;S(0.121)S(0.121)S(0.757)PAPADIAQTVQEDLR;S(0.028)S(0.028)S(0.944)PAPADIAQTVQEDLR;S(0.142)S(0.142)S(0.715)PAPADIAQTVQEDLR;S(0.018)S(0.018)S(0.964)PAPADIAQTVQEDLR;SS(0.001)S(0.999)PAPADIAQTVQEDLR;S(0.03)S(0.03)S(0.941)PAPADIAQTVQEDLR;SS(0.003)S(0.996)PAPADIAQT(0.001)VQEDLR;SS(0.01)S(0.99)PAPADIAQTVQEDLR;S(0.001)S(0.001)S(0.999)PAPADIAQTVQEDLR;S(0.027)S(0.027)S(0.946)PAPADIAQTVQEDLR;S(0.002)S(0.01)S(0.989)PAPADIAQTVQEDLR;S(0.032)S(0.032)S(0.931)PAPADIAQT(0.006)VQEDLR;S(0.052)S(0.052)S(0.885)PAPADIAQT(0.011)VQEDLR;SS(0.021)S(0.979)PAPADIAQTVQEDLR;S(0.003)S(0.003)S(0.993)PAPADIAQTVQEDLR;S(0.001)S(0.001)S(0.999)PAPADIAQTVQEDLR;S(0.005)S(0.176)S(0.819)PAPADIAQTVQEDLR;S(0.009)S(0.009)S(0.982)PAPADIAQTVQEDLR;S(0.003)S(0.189)S(0.808)PAPADIAQTVQEDLR;S(0.19)S(0.19)S(0.619)PAPADIAQTVQEDLR;S(0.002)S(0.002)S(0.996)PAPADIAQTVQEDLR 351.96 7.992699999999997e-248 17770558990.0 11689546.690000001 13078052.96 16248157.600000001 15962467.87 18264219.810000002 17128573.819999997 16200951.299999999 15743706.700000001 14307717.410000002 12621381.31 True False 13668356.065545812 14376355.628027825 16635575.298664827 15068142.546262978 14685477.049029421 16230321.255748285 14666279.908133917 15330451.080961088 14516940.709579242 14909537.830703493 0.9167524990210165 0.9642388510811062 1.115767335484194 1.010637802282031 0.984971983423077 1.0885864766595834 0.9836844089111447 1.0282311400284185 0.9736680556042611 1.0 23.829732201531996 -5.009704364430502 23.479420388193773 1.024425323561083 0.928623962876558 0.3830311617783043 0.04381188560403352 189.87295147444283 459412.4842889487 0.010683872501801197 0.03379339794900762 9.779026782656773e-06 5.009704364430502 -0.09580136068452494 SSS(ph)PAPADIAQTVQEDLR ddPTM_PC-9_Lapatinib_30min_R1 33 SSSPAPADIAQTVQEDLR 18 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 1 S(0.004)S(0.011)S(0.985)PAPADIAQTVQEDLR;S(0.001)S(0.017)S(0.982)PAPADIAQTVQEDLR;SS(0.097)S(0.903)PAPADIAQTVQEDLR;S(0.279)S(0.279)S(0.441)PAPADIAQTVQEDLR;SS(0.001)S(0.999)PAPADIAQTVQEDLR;S(0.001)S(0.025)S(0.974)PAPADIAQTVQEDLR;S(0.118)S(0.118)S(0.763)PAPADIAQTVQEDLR;S(0.004)S(0.096)S(0.9)PAPADIAQTVQEDLR;S(0.002)S(0.002)S(0.995)PAPADIAQTVQEDLR;S(0.001)S(0.23)S(0.769)PAPADIAQTVQEDLR;S(0.006)S(0.006)S(0.988)PAPADIAQTVQEDLR;S(0.036)S(0.036)S(0.927)PAPADIAQTVQEDLR;S(0.001)S(0.001)S(0.999)PAPADIAQTVQEDLR;S(0.04)S(0.04)S(0.92)PAPADIAQTVQEDLR;SSS(1)PAPADIAQTVQEDLR;S(0.113)S(0.378)S(0.509)PAPADIAQTVQEDLR;S(0.007)S(0.007)S(0.985)PAPADIAQTVQEDLR;SS(0.078)S(0.921)PAPADIAQTVQEDLR;S(0.095)S(0.022)S(0.883)PAPADIAQTVQEDLR;S(0.184)S(0.184)S(0.632)PAPADIAQTVQEDLR;S(0.053)S(0.053)S(0.893)PAPADIAQTVQEDLR;S(0.003)S(0.003)S(0.995)PAPADIAQTVQEDLR;S(0.083)S(0.023)S(0.871)PAPADIAQT(0.023)VQEDLR;SS(0.006)S(0.994)PAPADIAQTVQEDLR;S(0.034)S(0.034)S(0.933)PAPADIAQTVQEDLR;S(0.001)S(0.024)S(0.975)PAPADIAQTVQEDLR;S(0.002)S(0.027)S(0.964)PAPADIAQT(0.007)VQEDLR;S(0.001)S(0.011)S(0.988)PAPADIAQTVQEDLR;S(0.004)S(0.111)S(0.885)PAPADIAQTVQEDLR;S(0.01)S(0.01)S(0.981)PAPADIAQTVQEDLR;S(0.156)S(0.156)S(0.688)PAPADIAQTVQEDLR;SS(0.051)S(0.949)PAPADIAQTVQEDLR;SS(0.015)S(0.984)PAPADIAQTVQEDLR 323.72 1.0616999999999997e-176 8312058260.0 4870927.8 6290312.600000001 6608812.86 5999170.4 7346812.6 6661063.899999999 5136922.900000001 6134639.2 6299636.9 5856438.9 True False 4801467.476353251 6275747.767650369 6065461.777406172 6440369.4038618 6914687.527257308 6376185.724695346 5402887.6326052165 6419676.932833462 5590105.4542045435 6868716.560650675 0.699034154919097 0.9136710930252545 0.8830560591412131 0.9376379629285071 1.0066928029713718 0.9282936147377334 0.7865934756366479 0.9346253956103445 0.8138500700740797 1.0 22.711609121851794 -4.760675914748298 24.940608448872606 0.9090675358833654 0.6990339048950667 0.4776870272069259 0.0666352567147456 16.45785777590469 537279.660276425 0.016639027985660696 0.09721042998967366 1.7350983038876848e-05 4.760675914748298 -0.21003363098829875 SSS(ph)PATEQSWMENDFDELREEGFR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSPATEQSWMENDFDELREEGFR 24 1 Q9UN81 Q9UN81 L1RE1 LINE-1 retrotransposable element ORF1 protein 1 S(0.058)S(0.172)S(0.55)PAT(0.034)EQS(0.186)WMENDFDELREEGFR 53.262 0.020133 2011200.0 2511.4 2758.6 2218.2 2750.2 4011.8 2883.3 2844.4 3914.9 3679.4 1168.2 True False 2475.5869754656464 2752.212631187879 2035.8281584996162 2952.458882398256 3775.83381150227 2759.9879803005797 2991.6691142439113 4096.800546045101 3264.9872262003237 1370.1218134713458 1.8068371374903447 2.0087357227127587 1.4858738387221455 2.1548878744714637 2.755838038908236 2.0144106554349817 2.1835059370846794 2.9900994975515585 2.3829904714297916 1.0 10.420088449292082 -5.966932482441246 10.23168729534974 2.3217522188474056 1.7953906111500464 0.11866798239077336 0.5138996279703871 0.7367077978321448 220.56696278732366 0.1381812669754543 0.20460357154490813 1.0791144736397187e-06 5.966932482441246 -0.5263616076973592 SSS(ph)PCRTPEPDNDAHLR ddPTM_PC-9_AZD4547_30min_R2 1 SSSPCRTPEPDNDAHLR 17 1 Q9Y2K6 Q9Y2K6 USP20 Ubiquitin carboxyl-terminal hydrolase 20 1 S(0.264)S(0.327)S(0.408)PCRT(0.001)PEPDNDAHLR 67.655 0.008722200000000001 6443600.0 7184.0 7936.8 10653.0 15159.0 11957.0 8546.1 7741.3 10640.0 7800.1 11344.0 True False 9468.362563517217 10502.215387416749 10511.734259453458 11664.326754215323 10296.976942843607 8011.711016007068 8430.26070311477 8995.83248287645 8212.397361780244 10946.850012844872 0.8649394622569214 0.9593824136709286 0.9602519671977916 1.0655418445058236 0.9406337833039903 0.7318736446197988 0.7701083593200626 0.8217736127124126 0.7502064385776673 1.0 13.418228169501281 -6.655425557293809 6.492561783471391 0.801409400929495 0.9667296569514688 0.4243178591388782 0.08287498232511818 0.1844777606914917 10.020186590794895 0.026635413090234296 0.026558355069547356 2.2109272003238614e-07 6.655425557293809 0.16532025602197387 SSS(ph)PCRTPEPDNDAHLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSPCRTPEPDNDAHLR 17 1 Q9Y2K6 Q9Y2K6 USP20 Ubiquitin carboxyl-terminal hydrolase 20 1 S(0.034)S(0.034)S(0.931)PCRTPEPDNDAHLR;S(0.162)S(0.162)S(0.672)PCRT(0.004)PEPDNDAHLR 87.13799999999999 0.0013902 9910000.0 24232.0 18336.5 27071.0 32512.0 29081.0 32876.0 28019.0 23362.0 31846.0 24352.0 True False 28333.998996184062 20156.82653829322 27716.475307339206 30690.45804532616 23382.786809705234 31151.92468510969 25364.837480006798 22748.772254085092 32311.687503287118 28766.82482967407 0.9849539934958851 0.7006969541351914 0.9634874711215473 1.0668698484119035 0.8128386413221734 1.082911474226217 0.8817392127977226 0.7907988590599985 1.1232274571351506 1.0 14.812118370342343 -1.5228787452805523 0.15891410443959944 1.0009488174385681 0.504345085287789 0.05792472625924194 0.1285274152687703 212.07918938657974 2.1855174224213183 0.38938870989949587 24.603138140760574 0.029999999999985164 1.5228787452805523 -0.49660373215077913 SSS(ph)PEAMDPPPPK ddPTM_PC-9_AZD4547_30min_R2 2 SSSPEAMDPPPPK 13 0 K7ERU0;K7ENY2;Q9UK33 K7ERU0 ZNF580 Zinc finger protein 580 1 S(0.002)S(0.031)S(0.966)PEAMDPPPPK;S(0.103)S(0.103)S(0.793)PEAMDPPPPK 124.47 0.00013503 18528800.0 62395.0 77518.0 96869.0 117160.0 97885.0 106187.0 89952.0 107019.0 87713.0 97772.0 True False 82235.31210337652 102574.17755288936 95584.45376691972 90150.57210395597 84295.35736808956 99547.1101036427 97957.55373988584 90481.67260196933 92349.33011036144 94349.03203948085 0.8716073745087785 1.0871778473568934 1.0130941643038998 0.955500763020356 0.893441676569779 1.0550941324123673 1.0382465153314449 0.9590100782815323 0.9788052735052689 1.0 16.52572009632584 SSS(ph)PEAMDPPPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSPEAMDPPPPK 13 0 K7ERU0;K7ENY2;Q9UK33 K7ERU0 ZNF580 Zinc finger protein 580 1 S(0.09)S(0.09)S(0.819)PEAMDPPPPK 127.52 0.00010225 8857900.0 103380.0 106300.0 113250.0 130380.0 148960.0 120780.0 141540.0 113440.0 114070.0 107260.0 True False 120880.19215192746 116852.761487774 115950.30950301667 123075.23129766341 119772.35731830723 114446.08417896178 128132.30653913988 110462.32019961538 115738.05795076171 126705.38893030748 0.954025658832995 0.9222398705713079 0.9151174269848421 0.9713496192759348 0.945282267230057 0.9032455931445129 1.0112616962931014 0.8718044365135379 0.9134422689347633 1.0 16.951118359749763 -10.56553727788709 4.535621345085722 1.000002991787313 0.9342237477435278 0.22242317974537718 0.03691061301926617 50870322.0203893 0.010481068773461976 1589.480184460128 0.008700386668509873 2.719335060577033e-11 10.56553727788709 -0.06577924404378521 SSS(ph)PEAMDPPPPK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSPEAMDPPPPK 13 0 K7ERU0;K7ENY2;Q9UK33 K7ERU0 ZNF580 Zinc finger protein 580 1 S(0.077)S(0.077)S(0.846)PEAMDPPPPK;S(0.042)S(0.022)S(0.937)PEAMDPPPPK 147.33 9.6066e-05 13846600.0 46107.0 63877.0 69933.0 55249.0 59630.0 66211.0 57164.0 62461.0 62238.0 46623.0 True False 45449.50572501176 63729.09673109121 64183.37868918653 59312.19576526114 56122.68063709065 63379.30987537945 60123.67221439986 65363.16608509108 55228.101044805044 54681.72342875752 0.8311644709630628 1.165455160061316 1.1737629076890437 1.084680438840529 1.0263517153077755 1.159058381873308 1.0995204328688073 1.1953384419247495 1.0099919604172567 1.0 15.738771093286019 -4.754245850160676 24.99790369533243 1.108787210754676 0.831163986765638 0.5841810040591116 0.0681976581710347 171.3980416645265 595566.3148606234 0.016282265762579278 0.16228451259261267 1.7609788900463703e-05 4.754245850160676 -0.27762322398903794 SSS(ph)PEDPGAEV ddPTM_PC-9_AZD4547_30min_R2 1 SSSPEDPGAEV 11 0 Q9Y5U2-2;Q9Y5U2 Q9Y5U2-2 TSSC4 Protein TSSC4 1 S(0.185)S(0.12)S(0.695)PEDPGAEV 91.93700000000001 0.021444 0.0 21227.0 22937.0 27207.0 35377.0 25805.0 26445.0 25380.0 26978.0 22999.0 25166.0 True False 27976.744450971608 30350.936692518142 26846.217403262002 27221.379219201506 22222.421176723183 24791.38996949565 27638.77083242513 22809.169992766994 24214.6801866109 24284.945999934243 1.1520200395359068 1.2497839893323346 1.1054674531017978 1.1209157812941075 0.9150698204881063 1.020854234947147 1.1381030385037696 0.9392308301953298 0.99710661027109 1.0 14.567774657934404 -5.816995827932489 1.955164307616922 1.0078051960324617 1.1933068332334407 0.5739578848609326 0.06556270958313055 0.23902531541227043 1.8662014669242686 0.02054763038233329 0.03875360605040544 1.5240673947420543e-06 5.816995827932489 0.185501637200979 SSS(ph)PEDPGAEV ddPTM_PC-9_Lapatinib_30min_R1 1 SSSPEDPGAEV 11 0 Q9Y5U2-2;Q9Y5U2 Q9Y5U2-2 TSSC4 Protein TSSC4 1 S(0.109)S(0.109)S(0.782)PEDPGAEV 143.4 3.6437e-05 0.0 23991.0 27323.0 30541.0 29915.0 32522.0 33053.0 24652.0 31909.0 37327.0 27450.0 True False 23648.88394058944 27259.735272220114 28030.036871669294 32115.04889351458 30609.11990071209 31639.400240306295 25928.35993683762 33391.60862953156 33122.84018926438 32194.69592517415 0.734558387988922 0.8467151028721095 0.8706414540089392 0.9975260821892935 0.9507503960233945 0.9827519512481666 0.8053612308406161 1.0371773259526735 1.0288291048391136 1.0 14.974535403517917 -3.733572510765493 0.6191312404283371 0.973774184971838 2.269714733407899e-09 0.58863424206965 0.06346421666837194 8.480075938574338 0.9229707580649356 0.029721779251564853 7.877094621802381 0.00018468324179489077 3.733572510765493 -0.9737741827021232 SSS(ph)PELVTHLK ddPTM_PC-9_AZD4547_30min_R2 1 SSSPELVTHLK 11 0 Q07960;H0YE29;E9PNR6 Q07960 ARHGAP1 Rho GTPase-activating protein 1 1 S(0.171)S(0.171)S(0.658)PELVTHLK 153.81 0.00026149 24055000.0 70789.0 63198.0 92128.0 118020.0 94147.0 91402.0 91215.0 104440.0 85848.0 86755.0 True False 93298.42949733026 83625.51759575192 90906.3225246341 90812.31239082354 81076.31414551278 85686.61849089964 99332.95829313081 88301.19779244525 90385.75001783439 83717.73385616684 1.1144404560403385 0.9988984859459603 1.0858669762946256 1.0847440346013868 0.9684485044089677 1.0235181310344053 1.1865223019986668 1.0547490206095775 1.0796487895040696 1.0 16.353245639557805 SSS(ph)PFLSK ddPTM_PC-9_AZD4547_30min_R2 1 SSSPFLSK 8 0 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 S(0.031)S(0.031)S(0.937)PFLSK 72.325 0.032987999999999996 6110200.0 72817.0 77713.0 86277.0 96128.0 98360.0 88530.0 78520.0 93648.0 71848.0 84047.0 True False 95971.2913123098 102832.20748945659 85132.91060760974 73967.17476279513 84704.41181718647 82994.20510491384 85508.12788660437 79176.85341695599 75645.73859940082 81104.54011191588 1.1833035632762277 1.2678970541915258 1.0496688655177024 0.9119979554871783 1.044385575706405 1.0232991271560188 1.054295206761693 0.9762320741563927 0.93269425478546 1.0 16.30749505618205 -5.377351989922336 4.544343950986252 0.9960596156700191 1.224116756985857 0.791858072758305 0.04706931005303268 0.09187508542785783 2.9847813155392156 0.012694940473289205 0.027814014868971254 4.194189127273478e-06 5.377351989922336 0.22805714131583799 SSS(ph)PGKLLGSGYGGLTGGSSR ddPTM_PC-9_AZD4547_30min_R2 1 SSSPGKLLGSGYGGLTGGSSR 21 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 S(0.119)S(0.119)S(0.761)PGKLLGSGYGGLTGGSSR 161.64 1.5243e-05 6891500.0 25650.0 8604.1 30331.0 103570.0 75145.0 29509.0 14997.0 25846.0 15527.0 43376.0 True False 33806.16644685645 11385.207062654034 29928.791122076665 79693.53664054902 64712.41384711742 27663.797565129422 16331.703946961376 21852.0945819948 16347.725521001239 41857.419442626866 0.8076505168502777 0.27199973658814564 0.7150175887717939 1.9039285675454352 1.546020149087725 0.6609054722794758 0.3901746491884651 0.5220602433923819 0.39055741463968513 1.0 15.353195750099477 -6.980501759805401 24.53639425490884 0.5343939648964585 1.0415862086496872 0.20519882818093416 0.44834735623346794 336.3304001423307 423233.00862183736 0.17836465033660898 0.15728082577526337 1.0459194522826086e-07 6.980501759805401 0.5071922437532287 SSS(ph)PGKLLGSGYGGLTGGSSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSPGKLLGSGYGGLTGGSSR 21 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 S(0.081)S(0.081)S(0.757)PGKLLGS(0.02)GY(0.006)GGLT(0.031)GGS(0.013)S(0.011)R 45.678999999999995 0.034033 15875000.0 169050.0 21311.0 45602.0 34459.0 19108.0 19044.0 10542.0 11754.0 28101.0 14949.0 True False 166639.31600002688 21261.65568884393 41852.77958881052 36993.22981185423 17984.105007773407 18229.532513732272 11087.813177597842 12300.13375008663 24935.96946335143 17532.91473170959 9.504370411306867 1.2126709114937195 2.387097652001731 2.109930401072972 1.0257339000940788 1.0397320007929314 0.6323998802974101 0.7015452900047998 1.4222375369369056 1.0 14.097778234142682 -4.761084144249037 24.999984362927478 1.296577028658468 9.504379600384853 0.9545722669917526 0.53815319020859 1.8045077203312516 126820.16892213248 0.15216428668123078 0.8656720938732418 1.733468106994866e-05 4.761084144249037 8.207802571726384 SSS(ph)PGKPQAVSSLNSSHSR ddPTM_PC-9_AZD4547_30min_R2 3 SSSPGKPQAVSSLNSSHSR 19 1 Q9UHB7;Q9UHB7-2;Q9UHB7-3 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 S(0.164)S(0.164)S(0.671)PGKPQAVSSLNSSHSR;S(0.1)S(0.1)S(0.8)PGKPQAVSSLNSSHSR;S(0.176)S(0.176)S(0.648)PGKPQAVSSLNSSHSR 102.84 0.00013529 62282500.0 51075.0 44564.0 196241.0 434160.0 292289.0 238270.0 110772.0 296912.0 160930.0 231767.0 True False 67315.78757400361 58968.441503482565 193638.71611840857 334071.11970513413 251709.71762539182 223370.93923356856 120630.49340620164 251031.0727590049 169436.4312548933 223652.90787438434 0.30098328796069945 0.2636605178261418 0.8658001273436008 1.4937034482590617 1.1254479989447117 0.9987392578817971 0.5393647440253909 1.1224136325560212 0.7575865338180984 1.0 17.77090199043048 -5.315346763873724 4.482315583427123 1.0064496043824347 0.27615634329338296 0.5938837077756931 0.2349670998771605 0.13918134165564305 5.963926329621767 0.06598296177375383 0.1510569636196921 4.83785932842221e-06 5.315346763873724 -0.7302932610890518 SSS(ph)PGKPQAVSSLNSSHSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSPGKPQAVSSLNSSHSR 19 1 Q9UHB7;Q9UHB7-2;Q9UHB7-3 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 S(0.157)S(0.157)S(0.686)PGKPQAVSSLNSSHSR 68.08800000000001 0.0036646 20845000.0 34499.0 35321.0 60566.0 33739.0 40645.0 52298.0 33060.0 41027.0 69940.0 29165.0 True False 34007.03793365821 35239.21639461577 55586.49727152097 36220.2786100046 38254.341011144556 50061.336452592455 34771.68503617764 42933.264196427095 62062.6206991495 34206.13139008028 0.9941795973899638 1.0302017492932591 1.6250448388221115 1.058882637061624 1.1183474849844683 1.4635193872613774 1.0165336921515002 1.2551335813694988 1.814371230449859 1.0 15.06196732843912 -8.020776883578115 24.891863635166878 1.4497078944827488 1.1959925348067897 0.09107596609524049 0.26760445355554796 1490.1982691969756 1785329.4869072791 0.16791605427224954 0.06504897439823858 9.53285783616283e-09 8.020776883578115 -0.25371535967595915 SSS(ph)PHDKNLPQK ddPTM_PC-9_AZD4547_30min_R2 1 SSSPHDKNLPQK 12 1 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 S(0.154)S(0.154)S(0.691)PHDKNLPQK 61.409 0.026395 6338300.0 11573.0 8309.1 24830.0 53241.0 41925.0 29872.0 19939.0 32949.0 22196.0 33490.0 True False 15252.973266646 10994.85408169345 24500.73797636622 40967.11001525022 36104.4374281775 28004.0991177453 21713.532373038815 27857.489142697003 23369.235245967902 32317.525293562656 0.4719721924278728 0.3402133666430059 0.758125436703736 1.267643782842818 1.1171782833065242 0.8665298120250392 0.6718810359332787 0.861993264943648 0.7231133892118538 1.0 14.980029107855843 -5.405843036961815 4.445316649055219 0.9242425473315146 0.4124120301865361 0.5982598307240405 0.16889262589837614 0.16390274667048038 5.162602978987725 0.050145571965567126 0.10922672185676001 3.9278687107507654e-06 5.405843036961815 -0.5118305171449784 SSS(ph)PIPLTPSK ddPTM_PC-9_AZD4547_30min_R2 2 SSSPIPLTPSK 11 0 Q8N5Y2;Q8N5Y2-3;Q8N5Y2-2;A0A3B3IT59;Q8N5Y2-6;Q8N5Y2-4;A0A3B3ITL5;A0A3B3ITF3;A0A3F2YNX2;A0A3B3IRN2 Q8N5Y2 MSL3 Male-specific lethal 3 homolog 1 SS(0.019)S(0.981)PIPLTPSK;S(0.037)S(0.037)S(0.926)PIPLTPSK 181.66 0.0016175999999999999 42814000.0 179023.0 172182.0 241461.0 322860.0 296560.0 233620.0 222405.0 249335.0 223250.0 211365.0 True False 235948.59009027603 227836.46429747425 238259.06937218527 248429.61513727572 255387.76299821836 219011.70446865502 242198.61414442534 210806.00489830776 235050.53922609185 203965.17568449848 1.1568082114921951 1.1170360995834938 1.1681360240668435 1.2180001527395863 1.2521145442654504 1.073770087141891 1.1874508152267518 1.0335392019292104 1.1524052497553674 1.0 17.637963326849224 -7.755685094515192 24.999830124570373 1.069729163690545 1.167269418460257 0.4021877762388343 0.058789886001733786 149.55005481875503 649737.3694638307 0.0286142256424204 0.015934674562865528 1.7551526959381463e-08 7.755685094515192 0.09754025476971195 SSS(ph)PIPLTPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSSPIPLTPSK 11 0 Q8N5Y2;Q8N5Y2-3;Q8N5Y2-2;A0A3B3IT59;Q8N5Y2-6;Q8N5Y2-4;A0A3B3ITL5;A0A3B3ITF3;A0A3F2YNX2;A0A3B3IRN2 Q8N5Y2 MSL3 Male-specific lethal 3 homolog 1 S(0.001)S(0.029)S(0.97)PIPLTPSK;S(0.026)S(0.169)S(0.805)PIPLTPSK;S(0.008)S(0.03)S(0.961)PIPLTPSK 137.4 9.098299999999999e-05 30931600.0 260371.0 281710.0 261936.0 312527.0 338858.0 312029.0 300932.0 276681.0 278581.0 225333.0 True False 304446.66773833975 309676.3070434697 268181.547637812 295017.1254162047 272461.20741250616 295665.6499443388 272425.54240099294 269418.4169177518 282654.7201015267 266184.0891649541 1.1437447996738617 1.163391501028311 1.0075040490929572 1.1083199087582685 1.023581868725678 1.1107562847646952 1.0234478824621671 1.0121507178094082 1.0618768424072327 1.0 18.022064812896076 -1.5228787452803376 0.34190776482344276 1.0264268601108184 2.5258891040345652 0.47037251161435656 0.042200528040670586 52.12464385415128 0.737778792212798 0.0353904383235427 49.988262155227225 0.029999999999999995 1.5228787452803376 1.4994622439237468 SSS(ph)PIPLTPSK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSPIPLTPSK 11 0 Q8N5Y2;Q8N5Y2-3;Q8N5Y2-2;A0A3B3IT59;Q8N5Y2-6;Q8N5Y2-4;A0A3B3ITL5;A0A3B3ITF3;A0A3F2YNX2;A0A3B3IRN2 Q8N5Y2 MSL3 Male-specific lethal 3 homolog 1 S(0.006)S(0.077)S(0.917)PIPLTPSK;S(0.018)S(0.018)S(0.964)PIPLTPSK 149.49 0.00031096 41471000.0 266650.0 245686.0 291280.0 223053.0 233197.0 237602.0 198228.0 229691.0 249110.0 177918.0 True False 262847.5221023794 245117.12916190329 267332.08277331485 239457.06170299478 219480.81094294201 227440.31633731423 208491.27590294668 240363.2823882207 221052.60855540627 208670.88923916707 1.2596271720542584 1.1746589572490083 1.2811182419743923 1.1475345822125782 1.0518036883016548 1.0899475109661065 0.9991392506311001 1.1518774049634184 1.0593361122933058 1.0 17.67086982491238 -6.0186342204269 3.732606743404608 1.0657259090173163 1.2317415013982778 0.7305854016717044 0.04881167927959861 0.11844491812421316 3.5854011449813035 0.013951319800413751 0.01987146565788866 9.580005966777738e-07 6.0186342204269 0.16601559238096142 SSS(ph)PPILTKPTLK ddPTM_PC-9_AZD4547_30min_R2 2 SSSPPILTKPTLK 13 1 A0A3B3ITI3;A0A3B3IS53;A0A3F2YNX6;Q92794 A0A3B3ITI3 KAT6A Histone acetyltransferase KAT6A 1 S(0.12)S(0.12)S(0.76)PPILTKPTLK;S(0.032)S(0.145)S(0.823)PPILTKPTLK 77.74600000000001 0.0074421999999999995 20607200.0 180829.0 183708.0 206886.0 158801.0 208400.0 247160.0 209231.0 258910.0 233210.0 206932.0 True False 238328.86052314265 243088.01839425936 204142.55646308916 122191.88290099263 179467.25724584865 231705.04612821163 227852.15366584458 218901.40865991887 245537.0044923486 199687.37366519845 1.193509915768293 1.2173429593091232 1.022310788689927 0.6119159196608145 0.8987411369671704 1.1603389932740311 1.141044370926867 1.0962205804105332 1.2296070602041318 1.0 17.60738358775704 -6.775009098081406 24.97389906556402 1.132431148132043 0.9823906524304004 0.14408868195358016 0.165759390846832 499.2890868027083 918892.9989529302 0.06557917265698825 0.058144819525736455 1.678768849046572e-07 6.775009098081406 -0.15004049570164268 SSS(ph)PPILTKPTLK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSPPILTKPTLK 13 1 A0A3B3ITI3;A0A3B3IS53;A0A3F2YNX6;Q92794 A0A3B3ITI3 KAT6A Histone acetyltransferase KAT6A 1 S(0.115)S(0.115)S(0.771)PPILTKPTLK;S(0.213)S(0.213)S(0.574)PPILTKPTLK 94.538 0.0017659000000000002 21406000.0 128954.0 179989.0 177101.0 156473.0 213946.0 188138.0 189159.0 180323.0 170328.0 153151.0 True False 127115.09231273262 179572.24652899159 162540.4394096298 167980.54639862623 201362.11691401975 180091.77631109857 198952.72745790446 188701.46488147628 151143.86700664484 179622.94628912007 0.7076773593732779 0.9997177434109845 0.904897969705973 0.9351842282346583 1.1210266899302967 1.0026100786768293 1.1076130949197953 1.050542087076912 0.8414507730174102 1.0 17.45461213622484 -4.192569255627497 1.247443242678277 1.010759913021763 2.0819023314279903e-33 0.499261366655387 0.08425918860161019 4.649950776609722 2.22986127120456 0.025143826288792387 8.663450235905245 6.418458601285839e-05 4.192569255627497 -1.010759913021763 SSS(ph)PPPR ddPTM_PC-9_AZD4547_30min_R2 3 SSSPPPR 7 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.127)S(0.039)S(0.833)PPPR;S(0.051)S(0.051)S(0.897)PPPR;S(0.031)S(0.031)S(0.939)PPPR 78.77 0.027844999999999998 55285400.0 57856.3 50892.4 49255.4 49058.1 46220.3 36008.0 33354.6 46760.9 56525.1 70957.4 True False 76253.39991420132 67342.37304487565 48602.241213093344 37748.51298508947 39803.409165452395 33756.414067748134 36323.094783577944 39535.077363584336 59512.90138772124 68473.2030237517 1.1136239659732414 0.9834850725694285 0.7097994407569104 0.5512888446593541 0.5812990689459284 0.4929872209430432 0.5304716762114712 0.5773802833477875 0.8691414854228106 1.0 16.063251879614974 -5.220067409328904 2.450856380730004 0.6240131873729896 1.1012599072381275 0.49959128151375953 0.1543713435191567 0.2273209521575009 2.5616471299577137 0.040869592315073006 0.14913221109922575 6.024660666148872e-06 5.220067409328904 0.4772467198651379 SSS(ph)PPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSSPPPR 7 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.004)S(0.206)S(0.79)PPPR;SS(0.002)S(0.998)PPPR;S(0.002)S(0.029)S(0.969)PPPR 122.18 0.0053001 51252000.0 61160.0 79805.0 76533.0 62368.0 171378.0 175963.0 77358.0 115872.0 158893.0 206672.0 True False 71513.18003493805 87727.51298712875 78357.83697301893 58873.723159784124 137797.7111472667 166735.1905148421 70030.09021658028 112830.4827765322 161216.50952897675 244139.997585348 0.2929187381921638 0.3593328166412405 0.320954525059443 0.2411473897848413 0.5644208753590018 0.6829490954531273 0.2868439866847247 0.46215484513998245 0.6603445200437411 1.0 17.89734914641334 -14.522878732981221 0.12214104768708658 2.954190274358075 0.14949122475462676 0.7089915228147159 0.12304568328749933 89.69930581697815 0.7036366480579074 42.777093917167726 1.204603552843514 3.0000000849592887e-15 14.522878732981221 -2.8046990496034483 SSS(ph)PPPR ddPTM_PC-9_Lapatinib_30min_R1 4 SSSPPPR 7 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 SS(0.001)S(0.999)PPPR;S(0.011)S(0.011)S(0.978)PPPR;S(0.014)S(0.022)S(0.964)PPPR;S(0.001)S(0.001)S(0.998)PPPR 141.52 0.0023729 55892000.0 73962.9 92213.2 53417.1 80350.5 99662.4 52891.600000000006 155800.0 134649.0 82925.40000000001 86562.0 True False 72908.17548286534 91999.68600096212 49025.35223396894 86259.7438114105 93800.45357581718 50629.549564341585 163866.56166474527 140905.28410034123 73585.46820882546 101524.12636338537 0.7181364479011133 0.9061854486850504 0.48289361346969356 0.8496477330192524 0.9239227850144425 0.4986947573734662 1.614065223060552 1.387899498844234 0.7248076968960161 1.0 16.631463087056012 -7.249347773421724 24.912177614540337 1.2140180845175415 0.7409587298255386 0.4185053126715572 0.2595770615194834 682.8334218185054 1406834.8254795438 0.09909787977103249 0.07615235901246536 5.631864879162306e-08 7.249347773421724 -0.4730593546920029 SSS(ph)PRGEASSLNGESH ddPTM_PC-9_AZD4547_30min_R2 1 SSSPRGEASSLNGESH 16 1 Q8IY57-3;Q8IY57;Q8IY57-5 Q8IY57-3 YAF2 YY1-associated factor 2 1 S(0.032)S(0.032)S(0.685)PRGEAS(0.226)S(0.025)LNGESH 84.62 0.023783000000000002 6811800.0 5156.6 2450.8 9786.1 22884.0 18710.0 8121.3 6931.2 10198.0 5252.1 11598.0 True False 6796.291536056923 3242.973171993873 9656.329919875847 17608.447354275595 16112.439458108534 7613.473827160717 7548.063372486413 8622.13342672688 5529.715283625342 11191.957550156449 0.6072477942843806 0.2897592451955414 0.862791864300885 1.573312557286232 1.4396444398489792 0.6802629292544351 0.6744185133530015 0.7703865376621585 0.4940793653696483 1.0 13.450174775194156 -11.219781957496773 4.328349679526076 1.0079364981970331 0.837243700781363 0.018144803069418236 0.3783332806359651 0.03394797968266569 0.00237723799677864 0.42918710098369556 0.09987094513603764 6.028621839493155e-12 11.219781957496773 -0.17069279741567012 SSS(ph)PRGEASSLNGESH ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSSPRGEASSLNGESH 16 1 Q8IY57-3;Q8IY57;Q8IY57-5 Q8IY57-3 YAF2 YY1-associated factor 2 1 S(0.125)S(0.125)S(0.75)PRGEASSLNGESH;SS(0.017)S(0.982)PRGEASSLNGESH;S(0.005)S(0.02)S(0.975)PRGEASSLNGESH 216.01 3.1801999999999993e-77 3021800.0 18002.199999999997 15517.3 19773.3 30738.300000000003 36177.0 39148.0 23088.3 37603.0 29010.6 20715.6 True False 21049.616900342713 17057.754993736926 20244.770462657838 29016.132705913198 29088.37654876746 37095.00996388472 20901.209079183456 36615.96109367186 29434.82514233692 24471.174295400615 0.8601800896943067 0.6970550243248013 0.8272905181531426 1.1857270254238192 1.1886792271441855 1.5158655451551732 0.8541154922472136 1.4962894976623118 1.2028366431058124 1.0 14.57879571306736 -5.756535683588658 3.833845964909852 1.2288517761585038 0.7735751733013223 0.4949045267417884 0.19037346955090315 0.16331305510666133 5.239768632832665 0.051345364747678916 0.08690215607577 1.7517184992220543e-06 5.756535683588658 -0.4552766028571815 SSS(ph)PRGEASSLNGESH ddPTM_PC-9_Lapatinib_30min_R1 3 SSSPRGEASSLNGESH 16 1 Q8IY57-3;Q8IY57;Q8IY57-5 Q8IY57-3 YAF2 YY1-associated factor 2 1 S(0.015)S(0.015)S(0.969)PRGEASSLNGESH;S(0.003)S(0.003)S(0.992)PRGEAS(0.001)S(0.002)LNGESH;S(0.001)S(0.003)S(0.813)PRGEAS(0.177)S(0.007)LNGESH 176.56 1.0151e-28 0.0 35288.0 15126.1 30519.4 18157.2 22245.6 22530.5 16787.7 9974.6 34978.4 14886.0 True False 34784.786648973364 15091.076444794811 28010.21274029087 19492.541058643586 20937.157544532347 21566.923036160726 17656.88496315304 10438.056330067555 31038.764253118807 17459.025265651817 1.9923670491162844 0.8643710754279271 1.6043400083392418 1.1164736153393642 1.199216864971452 1.2352879217484507 1.0113328032058286 0.5978601995956193 1.777806250969991 1.0 14.09168539535158 -4.748807656562503 24.996842357218778 1.1557680631391773 1.9923690103813043 0.37709228711288434 0.3223666291628789 637.9928549668614 1262444.8035461255 0.07610904533235038 1.3392431025454388 1.7831683349001174e-05 4.748807656562503 0.836600947242127 SSS(ph)PSASLTENEVK ddPTM_PC-9_AZD4547_30min_R2 2 SSSPSASLTENEVK 14 0 O96028-5 O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 S(0.182)S(0.182)S(0.608)PS(0.028)ASLTENEVK;S(0.007)S(0.181)S(0.798)PS(0.014)ASLTENEVK 163.8 1.0058e-08 6115800.0 41040.0 35412.0 47135.0 64585.0 58160.0 49997.0 40156.0 51819.0 40225.0 44898.0 True False 54089.86631497034 46858.236480596956 46509.95910253813 49695.92607830312 50085.48791467623 46870.679686325384 43729.80620752028 43811.56423215926 42351.211379034925 43326.13468588762 1.2484350775142823 1.081523584328879 1.073485078688258 1.147019609263466 1.1560109914672425 1.0818107829404942 1.0093170444250166 1.0112040815501078 0.9774980317556403 1.0 15.402949912761017 -7.1302222012680865 2.4899721160562986 0.997582141315529 1.1344529848580729 0.6787690876332478 0.045801580372551026 0.18944306476999914 2.2922115007349517 0.020479732492179117 0.014960308048238256 7.409310563210466e-08 7.1302222012680865 0.13687084354254386 SSS(ph)PSASLTENEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSPSASLTENEVK 14 0 O96028-5 O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 S(0.01)S(0.033)S(0.952)PS(0.006)ASLTENEVK 161.49 0.00051484 5848000.0 22039.0 20762.0 19442.0 25143.0 29270.0 21742.0 20147.0 24163.0 14315.0 19795.0 True False 25769.76740990841 22823.114148722147 19905.571014195582 23734.319224705825 23534.75361645309 20601.81124539647 18238.530308351368 23528.746852814744 14524.329793680678 23383.676802866223 1.1020408649656719 0.9760276085377914 0.8512592430184326 1.014995179107018 1.0064607809482018 0.8810338690137571 0.7799684567191677 1.006203902456039 0.6211311384486967 1.0 14.513214173756257 -6.865212186903327 4.968626402988948 0.8497805092385711 0.9827304126300904 0.24264652176321766 0.11728538615273594 0.3195744056943975 12.776308700141508 0.04019458266547974 0.03551815925371067 1.3639165935851768e-07 6.865212186903327 0.13294990339151935 SSS(ph)PSASLTENEVK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSPSASLTENEVK 14 0 O96028-5 O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 S(0.028)S(0.028)S(0.944)PSASLTENEVK 164.66 0.00051368 4715700.0 27101.0 27230.0 23223.0 20473.0 23579.0 24362.0 22423.0 25319.0 22658.0 18612.0 True False 26714.534770285263 27166.95060800621 21313.694583372377 21978.652715925935 22192.129578097607 23320.094050595755 23583.953223418383 26495.413171553788 20106.017440682408 21829.059401068876 1.2238060412707092 1.2445314343995948 0.9763908829864073 1.0068529436888944 1.0166324242542009 1.0683050342267093 1.0803925533439878 1.2137679725337327 0.9210665961950656 1.0 14.41396234649524 -5.25053430785127 24.832891679360646 1.0441491482986764 1.2341687727665809 0.533538960994622 0.07397312752867831 529.8339405315746 1206524.7547893757 0.01905129674691948 0.049339456562517425 5.616499080874699e-06 5.25053430785127 0.19001962446790444 SSS(ph)PTAGPSTEGAEGPEEK ddPTM_PC-9_AZD4547_30min_R2 1 SSSPTAGPSTEGAEGPEEK 19 0 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;A0A0C4DGG3 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 S(0.033)S(0.033)S(0.92)PT(0.014)AGPSTEGAEGPEEK 219.23 1.2020999999999996e-86 0.0 19585.0 25840.0 25280.0 27542.0 23122.0 26458.0 17597.0 26714.0 20297.0 23296.0 True False 25812.622606693316 34192.274671259074 24944.77068234144 21192.617419658207 19911.909414772086 24803.57707744058 19163.098910093977 22585.96512665052 21369.857982853246 22480.41413075054 1.1482271837414555 1.520980639964639 1.1096223822771998 0.9427147247554136 0.8857447776077646 1.1033416436716006 0.8524353154100097 1.0046952425024767 0.9505989462009872 1.0 14.456380992460462 -5.495858048679354 4.888701684363487 0.9639625109452944 1.3353262809782653 0.6611162046728593 0.10571724823746798 0.09896027402724936 6.140239827204696 0.026352146649874526 0.05334794280101132 3.192581195691208e-06 5.495858048679354 0.37136377003297094 SSS(ph)PTAGPSTEGAEGPEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSPTAGPSTEGAEGPEEK 19 0 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;A0A0C4DGG3 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 S(0.001)S(0.033)S(0.963)PT(0.003)AGPSTEGAEGPEEK 197.51 5.9259999999999995e-59 0.0 24982.0 31843.0 24894.0 30310.0 30490.0 31771.0 28363.0 27813.0 22813.0 24161.0 True False 29210.959183008832 35004.16259694439 25487.56737102074 28611.828966345853 24515.703374296383 30104.87283035101 25676.251309662475 27082.938220309414 23146.596967044177 28541.19804162924 1.0234664690810351 1.2264433520235727 0.8930097234827152 1.0024747007681174 0.8589584550213553 1.0547865855680287 0.8996206561550764 0.9489068461950035 0.8109889757705098 1.0 14.800758274014179 -5.2727646649007145 24.956450001467225 0.9346780344053442 1.1249549148526716 0.46246978270562433 0.08251630066089735 507.24376204075276 1117765.4119664794 0.020082339933955546 0.04243774173198606 5.3362397683273334e-06 5.2727646649007145 0.19027688044732738 SSS(ph)PTAGPSTEGAEGPEEK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSPTAGPSTEGAEGPEEK 19 0 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;A0A0C4DGG3 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 SS(0.002)S(0.993)PT(0.005)AGPSTEGAEGPEEK 265.93 2.1288999999999995e-78 7132600.0 36104.0 34627.0 32262.0 30367.0 36667.0 37944.0 35374.0 30919.0 39755.0 33485.0 True False 35589.15033933728 34546.82330897653 29609.54289492139 32600.29048134238 34510.31915009566 36321.223571784125 37205.49263368868 32355.60961535888 35277.37326129091 39272.83763404209 0.9062026704301155 0.8796620104433451 0.7539445754043386 0.8300976564291888 0.8787325090097837 0.9248433716513657 0.9473594187510043 0.823867374108784 0.8982639245479968 1.0 15.26124422233751 -6.481992985609287 3.9348299481067324 0.9093475803798813 0.839414083438014 0.28782740114574845 0.05554172073471629 0.3390129235381917 11.121118636348932 0.018929121369091206 0.020712352583560786 3.296150358232131e-07 6.481992985609287 -0.06993349694186723 SSS(ph)PTQYGLTK ddPTM_PC-9_AZD4547_30min_R2 2 SSSPTQYGLTK 11 0 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 SS(0.083)S(0.914)PT(0.002)QYGLTK;S(0.004)S(0.074)S(0.923)PTQYGLTK 188.15 0.00011464 366450000.0 193029.0 175931.0 233013.0 312571.0 277177.0 251807.0 216180.0 255003.0 200571.0 238372.0 True False 254408.20674737846 232797.25523178343 229923.09537201034 240512.5851238104 238695.75797328405 236061.46848359954 235419.60120384878 215598.14573599095 211172.77358618804 230026.66883479035 1.105994396371924 1.0120446312204912 0.9995497328057452 1.0455856546640303 1.0376873220066496 1.026235217331011 1.0234448135791234 0.9372745639803954 0.9180360462371276 1.0 17.811441608498875 -7.716679237631645 5.44738440424978 0.9455169389776905 1.0342151571061042 0.5749542953175696 0.03301786200890457 0.12606160077401937 8.60047470417513 0.016087208614386308 0.008814908051908887 1.9200863595588756e-08 7.716679237631645 0.08869821812841372 SSS(ph)PTQYGLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSSPTQYGLTK 11 0 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 SS(0.016)S(0.983)PT(0.001)QYGLTK;S(0.001)S(0.011)S(0.981)PT(0.007)QYGLTK;S(0.001)S(0.445)S(0.544)PT(0.009)QYGLTK 114.56 0.0014457 136490400.0 163247.0 149357.0 188643.0 200900.0 210951.0 181279.0 209508.0 189309.0 173958.0 139906.0 True False 190881.4928247799 164184.17589397417 193140.96455256097 189644.22432658816 169616.66587442427 171772.4101165591 189661.88553343358 184339.83933946525 176501.8066537972 165269.85030471376 1.1549686314403085 0.993430898565359 1.1686400404941388 1.147482278086018 1.0263013221207384 1.039345106199687 1.1475891409337358 1.1153869807444703 1.0679613149547524 1.0 17.334464036434667 -6.2496058917634185 24.908190354646678 1.0746036390273603 1.1111168865002572 0.13014899512509248 0.06048189004405349 2085.5549153689844 4389860.827355196 0.018322313188343164 0.02347026589994511 5.628518634212314e-07 6.2496058917634185 0.03651324747289686 SSS(ph)PTQYGLTK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSPTQYGLTK 11 0 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 S(0.008)S(0.083)S(0.907)PT(0.002)QYGLTK;SS(0.004)S(0.996)PTQYGLTK 185.57 0.00019188 202166000.0 869940.0 710810.0 787490.0 682790.0 739160.0 757690.0 692400.0 644440.0 753740.0 571460.0 True False 857534.4960725429 709164.1631170373 722745.6119993066 733004.6543206677 695684.0620444731 725285.3649616577 728249.0840607797 674383.0350438856 668845.8639659261 670236.0995774147 1.2794513703651895 1.0580811203159108 1.0783447988775885 1.0936514084855005 1.0379686538566089 1.0821341396247557 1.0865560427436576 1.006187275601964 0.997925752414164 1.0 19.354309868049818 -2.571086076611038 1.467255535675979 1.049314619819391 170.36017752320768 0.7806800233141833 0.03634020060194655 503.2448062340703 1.9608812052805469 0.010577899247941683 286036.6291435111 0.002684812266563124 2.571086076611038 169.31086290338828 SSS(ph)PTSSLTQPIEMPT(ph)LSSSPTEERPTVGPGQQDNPLLK ddPTM_PC-9_AZD4547_30min_R2 1 SSSPTSSLTQPIEMPTLSSSPTEERPTVGPGQQDNPLLK 39 1 Q7LBC6;Q7LBC6-2 Q7LBC6 KDM3B Lysine-specific demethylase 3B 2 S(0.151)S(0.151)S(0.476)PT(0.151)S(0.042)S(0.014)LT(0.016)QPIEMPT(0.234)LS(0.234)S(0.234)S(0.234)PT(0.064)EERPTVGPGQQDNPLLK 93.18700000000001 2.2659000000000004e-15 5369200.0 13075.0 15282.0 19938.0 21910.0 20075.0 19407.0 14720.0 18505.0 13459.0 17901.0 True False 17232.578023105183 20221.607644202046 19673.60909274223 16858.988006125597 17287.932769723626 18193.47722208365 16030.051483581492 15645.47745259669 14170.41526290692 17274.29143864034 0.9975852314589385 1.1706186454032461 1.1388952862480328 0.9759582942090602 1.0007896897613278 1.0532112003961687 0.9279715779093756 0.9057087816406637 0.8203181770575867 1.0 14.076338914537821 -6.821670909760515 0.8103936396265137 0.8966079969022619 1.0961656571452836 0.4874519846217459 0.07093616941122657 0.515471957642997 0.732972420363313 0.04957920499930742 0.04448831631315737 1.5077491428197455e-07 6.821670909760515 0.19955766024302168 SSS(ph)PTSYWK ddPTM_PC-9_AZD4547_30min_R2 2 SSSPTSYWK 9 0 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614;Q92614-5;Q92614-2 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 S(0.267)S(0.267)S(0.464)PT(0.001)SYWK;SS(0.026)S(0.97)PT(0.002)S(0.002)YWK 110.39 0.0023052 49024300.0 127041.0 162310.0 156337.0 178737.0 177565.0 156884.0 151000.0 195077.0 150970.0 150198.0 True False 167437.39538304482 214773.53335495602 154263.86923121882 137531.94610912248 152913.16474500467 147074.01867931042 164438.70747423917 164932.33207350475 158949.9659886365 144939.6137367134 1.1552217579881179 1.4818138935094567 1.0643320018186553 0.9488913524976882 1.0550129174676528 1.0147261669019916 1.134532535549228 1.137938261468729 1.0966633751168489 1.0 17.145092429102746 -5.292453146797733 21.712586195649305 1.0588352012572224 1.3185175903654347 0.5657013442557401 0.09180916877246427 80.82677396969174 56586.32975654712 0.023495923902834923 0.04893107468653964 5.099726122299426e-06 5.292453146797733 0.2596823891082123 SSS(ph)PTSYWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSSPTSYWK 9 0 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614;Q92614-5;Q92614-2 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 S(0.019)S(0.174)S(0.806)PT(0.001)SYWK;S(0.001)S(0.187)S(0.812)PTSYWK;S(0.005)S(0.024)S(0.968)PT(0.003)S(0.001)YWK;S(0.007)S(0.007)S(0.958)PT(0.008)S(0.02)YWK 140.49 0.000772 55738900.0 238063.0 286840.0 260808.0 239621.0 282279.0 220865.0 259957.0 212038.0 214181.0 201980.0 True False 278362.36394142354 315315.5795404803 267026.65183984785 226195.81223176332 226968.45630675644 209282.45058938858 235331.9910343023 206472.22717283183 217312.99193435765 238597.37512719975 1.1666614680610987 1.321538342039098 1.119151674227313 0.9480230539467378 0.9512613296175461 0.8771364331976287 0.9863142497223341 0.8653583345699359 0.9107937244427141 1.0 17.864218646087714 -5.6288671910932395 2.8191796007522076 0.9266760995701545 1.2439301696966043 0.8463922955932836 0.05397627440478961 0.08378764020678948 1.333758906618417 0.01445177865288753 0.028567456911668565 2.3503514573897897e-06 5.6288671910932395 0.3172540701264498 SSS(ph)PTSYWK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSPTSYWK 9 0 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614;Q92614-5;Q92614-2 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 SS(0.016)S(0.965)PT(0.015)S(0.004)YWK;S(0.03)S(0.133)S(0.833)PT(0.001)S(0.003)YWK 121.9 0.0015889 93374000.0 151499.0 187259.0 185385.0 158893.0 191260.0 194644.0 185399.0 202639.0 199141.0 169773.0 True False 149338.5964784861 186825.41329065894 170143.36090679455 170578.52127150947 180010.46283162784 186319.52985732543 194998.0530557258 212054.34771003984 176711.6435323037 199118.0368416972 0.7500003457608075 0.9382646406823951 0.8544849256527268 0.8566703648606318 0.904038959437611 0.9357240198458423 0.9793088368521488 1.0649680514810784 0.8874718048410298 1.0 17.603264386019916 -6.764434538545131 1.4832894638027945 0.9883956186153173 0.8550690428450443 0.5053004634098686 0.05882334785938915 0.32982081796624996 1.5109447404547562 0.025535284786715205 0.023077522822953105 1.7201466003764236e-07 6.764434538545131 -0.13332657577027307 SSS(ph)PVGLAK ddPTM_PC-9_AZD4547_30min_R2 2 SSSPVGLAK 9 0 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 S(0.001)S(0.026)S(0.973)PVGLAK;S(0.001)S(0.016)S(0.983)PVGLAK 139.43 0.00083171 234240000.0 521470.0 490690.0 622900.0 807160.0 752750.0 629090.0 582570.0 666330.0 566200.0 579510.0 True False 687286.6127501852 649295.9465340598 614639.9390043702 621081.7324976868 648243.6559108063 589752.9028515796 634417.6014123696 563364.009240137 596128.17607979 559221.5312891166 1.2290059918935046 1.1610710786426692 1.0990992023992767 1.1106184181892462 1.159189372441501 1.0545962017808617 1.1344656203596295 1.0074075794997934 1.065996466025899 1.0 19.093060383229606 -1.522878745281457 0.1476204636221391 0.9790637148735719 1.7910147223042603 0.6878485309111311 0.03827115623850845 41.02312462098836 0.3999742154903427 0.14085479271637596 7.104348013705722 0.029999999999922675 1.522878745281457 0.8119510074306884 SSS(ph)PVGLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSPVGLAK 9 0 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 S(0.003)S(0.059)S(0.938)PVGLAK;S(0.036)S(0.036)S(0.928)PVGLAK 77.533 0.02292 99081000.0 277467.0 274706.0 272752.0 324175.0 342659.0 317847.0 308254.0 292527.0 266282.0 235839.0 True False 324436.68287694734 301976.99621129263 279255.44209772 306012.5257395308 275517.4287482138 301178.5437823355 279053.9495543035 284848.47620797635 270175.87049394916 278594.7437995033 1.1645470350669471 1.0839292661910982 1.0023715389931842 1.0984145700888 0.9889541525108451 1.081063266574351 1.0016482929596497 1.0224474170732154 0.9697809327242262 1.0 18.087808513546385 -1.5228787452803376 0.5926949586815328 1.0142209193516618 9.74095162646917 0.5919954840191194 0.03771026841312155 115.84169756753415 0.9208006089511457 0.016636055748524302 1306.260307888675 0.029999999999999995 1.5228787452803376 8.72673070711751 SSS(ph)PVGLAK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSPVGLAK 9 0 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 S(0.02)S(0.02)S(0.96)PVGLAK;S(0.001)S(0.025)S(0.975)PVGLAK 128.91 0.0013151 236760000.0 791700.0 603370.0 680620.0 625080.0 651110.0 607070.0 605400.0 568150.0 677100.0 510990.0 True False 780410.212820001 601972.9338359423 624662.0508691785 671050.4684057515 612812.9899315123 581107.0312492884 636744.6497550495 594548.3231335481 600837.8678209045 599313.9406486229 1.3021726342213598 1.0044367284105582 1.0422952120771993 1.1196977458583557 1.0225241703342987 0.9696204140026683 1.0624559293012878 0.9920482118104627 1.0025427861241343 1.0 19.19295240728178 -4.7586205066984 24.999951912858343 1.0267345281144615 1.302173003742536 0.8089084816983675 0.04054674033169627 33.88062331714225 300423.2557960886 0.010530424082675542 0.07104046711069568 1.7433295566184406e-05 4.7586205066984 0.27543847562807455 SSS(ph)PVQVEEEPVR ddPTM_PC-9_AZD4547_30min_R2 4 SSSPVQVEEEPVR 13 0 A0A0J9YVR0;Q8IZ21-3;Q8IZ21;Q8IZ21-2 A0A0J9YVR0;Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 S(0.205)S(0.205)S(0.59)PVQVEEEPVR;S(0.048)S(0.224)S(0.728)PVQVEEEPVR;SSS(1)PVQVEEEPVR;SS(0.003)S(0.997)PVQVEEEPVR 159.41 5.7685e-05 299403600.0 157298.0 153834.0 245014.0 286792.0 303589.0 257260.0 201465.0 280390.0 201427.0 208231.0 True False 207315.49199834812 203557.83211216997 241764.95427069665 220676.53529223072 261440.90767759059 241173.49153157303 219394.99471058024 237062.16822121464 212074.0199986293 200940.8960705832 1.031723735946344 1.0130234118228851 1.2031645075663118 1.0982161402062978 1.3010836160786101 1.2002210413496792 1.0918384410583837 1.1797606801650937 1.0554049680565545 1.0 17.61641168984616 -5.249617035834053 24.45076360664652 1.1521495747875035 1.02237354492964 0.2438816964038708 0.08190679278768459 692.8583087141496 1432948.6581920118 0.02034091347982584 0.052839285357362584 5.6283742073151635e-06 5.249617035834053 -0.1297760298578634 SSS(ph)PVQVEEEPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSSPVQVEEEPVR 13 0 A0A0J9YVR0;Q8IZ21-3;Q8IZ21;Q8IZ21-2 A0A0J9YVR0;Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 SS(0.008)S(0.991)PVQVEEEPVR;S(0.003)S(0.003)S(0.995)PVQVEEEPVR;S(0.003)S(0.011)S(0.986)PVQVEEEPVR 212.03 1.004e-10 255629000.0 79408.0 81266.0 124599.0 102138.0 110683.0 104549.0 110308.0 100158.0 99630.0 78156.0 True False 92850.20602050939 89333.55141171649 127569.91270433867 96415.53899586372 88995.46069456376 99066.26639200415 99858.82767923891 97528.95862617322 101086.90026855796 92325.0641174443 1.005687966838529 0.9675980435613628 1.3817473502326554 1.0443051398612195 0.9639360832867114 1.073015950099797 1.0816004151614897 1.0563649162713733 1.0949020315866551 1.0 16.494434738896253 SSS(ph)PVQVEEEPVR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSPVQVEEEPVR 13 0 A0A0J9YVR0;Q8IZ21-3;Q8IZ21;Q8IZ21-2 A0A0J9YVR0;Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 S(0.342)S(0.057)S(0.601)PVQVEEEPVR;S(0.008)S(0.069)S(0.923)PVQVEEEPVR 214.89 2.2347e-14 254190000.0 109346.0 88431.0 129170.0 86750.0 100833.0 104943.0 99749.0 84917.0 132841.0 87073.0 True False 107786.7059883997 88226.24345268462 118550.14121061936 93129.88438951671 94902.20118530546 100454.83252408143 104913.51514439465 88862.5538247494 117879.04770225506 102123.45203252042 1.0554549796659425 0.8639175595492958 1.1608512917568434 0.9119343552924574 0.9292890055761588 0.983660760822033 1.0273204935433025 0.8701483553107058 1.1542798970868846 1.0 16.63995468488188 -8.271663311403897 24.982183122637245 1.0771399245773035 0.9761567940720269 0.16302091982767553 0.09226700089684124 1368.4892423276206 3343866.5910780607 0.07949958370549046 0.021427794162222145 5.3497894331414195e-09 8.271663311403897 -0.10098313050527652 SSS(ph)PVT(ph)ELASRSPIR ddPTM_PC-9_AZD4547_30min_R2 1 SSSPVTELASRSPIR 15 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 S(0.011)S(0.043)S(0.946)PVT(0.989)ELAS(0.007)RS(0.004)PIR 130.27 0.002848 3794000.0 26900.0 27214.0 31582.0 36573.0 37361.0 43137.0 34505.0 33955.0 34911.0 33102.0 True False 35453.64044524126 36010.39330122461 31163.202044687783 28141.65989721731 32174.070047802958 40439.63657077462 37575.878154957805 28708.03495827722 36756.32418778094 31943.109055464636 1.109899489861212 1.1273290035324275 0.9755844990097032 0.88099313840595 1.0072303854937004 1.2659893719348665 1.1763375346373663 0.8987238815241756 1.1506808596482843 1.0 14.963217118116015 SSS(ph)PVTELAS(ph)RSPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSPVTELASRSPIR 15 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 S(0.214)S(0.283)S(0.503)PVT(0.002)ELAS(0.968)RS(0.03)PIR 103.73 0.0039581 11145000.0 46271.0 49893.0 53578.0 64093.0 62667.0 47932.0 54034.0 47586.0 48604.0 40025.0 True False 54103.76640609248 54846.047308650115 54855.50271569652 60502.07700230959 50387.851208823544 45418.361540536476 48915.508347717165 46336.91792153469 49314.7415502659 47281.21566227434 1.144297278491125 1.1599965555118277 1.1601965378285672 1.2796218573242855 1.0657054921924942 0.9606005451500217 1.0345653694083594 0.9800280570727138 1.043009170967956 1.0 15.52897950912978 -6.480064980104601 6.5542756325406595 1.0050002827702411 1.1819258669903692 0.8145191653444686 0.041088959572674326 0.0887890478647142 10.355852344176956 0.012756080812929078 0.0142141685526471 3.31081580615319e-07 6.480064980104601 0.17692558422012805 SSS(ph)PVTELAS(ph)RSPIR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSPVTELASRSPIR 15 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 S(0.148)S(0.187)S(0.664)PVTELAS(0.817)RS(0.183)PIR 80.541 0.031353 12160000.0 17131.0 20263.0 28072.0 24298.0 26405.0 22031.0 19211.0 22297.0 26183.0 20211.0 True False 16886.70879855936 20216.08226845501 25764.028521053682 26084.955975751855 24851.90981422739 21088.785486769357 20205.65157985507 23333.0000192004 23233.994820786826 23704.444420535314 0.712385766102592 0.8528393203319158 1.086885989141097 1.1004246930653345 1.048407183620723 0.8896553368911698 0.8523992894071284 0.9843301789847845 0.9801535276928518 1.0 14.53286995944643 -4.985265333443295 3.909431732525717 0.9892027001833698 0.7259581015548616 0.5904217671649483 0.07427653612229697 0.16881653106567726 5.7408618189546345 0.02195955368790773 0.0948694429787593 1.0345099367928972e-05 4.985265333443295 -0.26324459862850813 SSS(ph)PVTELASR ddPTM_PC-9_AZD4547_30min_R2 3 SSSPVTELASR 11 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SS(0.004)S(0.996)PVTELASR;S(0.008)S(0.004)S(0.988)PVTELASR;SS(0.006)S(0.993)PVT(0.001)ELASR 206.36 5.6442999999999995e-06 527160000.0 589320.0 722920.0 766280.0 766240.0 825410.0 886190.0 760990.0 1004960.0 760780.0 677040.0 True False 776711.5013825106 956589.7525288941 756118.6265215421 589595.2062899891 710816.0691137012 830776.3992084448 828716.6357670312 849666.5236834148 800993.2776368478 653337.0356749364 1.1888373978066635 1.4641596913921764 1.1573178700032307 0.9024365283087034 1.0879776138503852 1.2715893234954956 1.2684366422162447 1.30050261547726 1.2260031712565838 1.0 19.317467898455853 -6.78187400115969 24.963091910957747 1.2355334001073277 1.1625611511839988 0.01971006317379842 0.15069094810059044 921.3888072880069 1125567.5230923228 0.057631983802344675 0.05088476832322902 1.652441139957446e-07 6.78187400115969 -0.07297224892332888 SSS(ph)PVTELASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SSSPVTELASR 11 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SS(0.002)S(0.998)PVTELASR;S(0.003)S(0.219)S(0.778)PVTELASR;S(0.001)S(0.063)S(0.934)PVT(0.001)ELASR;SS(0.027)S(0.972)PVT(0.001)ELASR;S(0.001)S(0.023)S(0.976)PVTELASR 203.03 1.2414999999999999e-46 301297000.0 603792.0 765670.0 757920.0 674290.0 792420.0 597480.0 729200.0 503149.0 589832.0 526421.0 True False 706002.060164409 841680.6574632557 775991.6872276082 636511.7173776755 637150.9894345663 566147.0969965727 660124.897049178 489941.8718804319 598457.1771474859 621856.9601536554 1.1353126287916149 1.3534955968898117 1.247862027685382 1.0235661223770802 1.0245941273651291 0.9104137016600774 1.061538166085762 0.787869081274529 0.9623711166626042 1.0 19.246223243524206 -5.867194715028898 2.493565933421075 0.9509402584569859 1.2626542125182603 0.6915286179299555 0.08575259114628225 0.1495178225295561 1.8881781280652938 0.025470771397017943 0.042804972860267174 1.3577045860755717e-06 5.867194715028898 0.31171395406127433 SSS(ph)PVTELASR ddPTM_PC-9_Lapatinib_30min_R1 5 SSSPVTELASR 11 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.001)S(0.014)S(0.985)PVTELASR;S(0.037)S(0.023)S(0.94)PVTELASR;S(0.021)S(0.002)S(0.977)PVTELASR;SS(0.001)S(0.993)PVT(0.005)ELASR;S(0.001)S(0.002)S(0.997)PVTELASR 191.33 0.00025235 556076000.0 679406.0 923807.0 908885.0 731769.0 972582.0 914203.0 905579.0 973213.0 928146.0 731649.0 True False 669717.5458521984 921667.9816500334 834159.9836975574 785585.7333698217 915376.6389297809 875104.6688012811 952465.4495879223 1018432.0288687313 823608.4236693284 858113.5547889865 0.7804532886290144 1.0740629564774504 0.9720857793729649 0.915479925687691 1.0667313595283734 1.0198005426175476 1.1099526913103446 1.1868266422142322 0.9597895512463465 1.0 19.710809047675532 -6.272006257323904 23.43390208732579 1.067294128591251 0.9480281861818699 0.299856996265661 0.08947275331878084 388.6158025022097 861821.5018729637 0.027097023513083473 0.031084207216342634 5.345566574380783e-07 6.272006257323904 -0.11926594240938104 SSS(ph)PVTELASRS(ph)PIR ddPTM_PC-9_AZD4547_30min_R2 1 SSSPVTELASRSPIR 15 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 S(0.187)S(0.234)S(0.569)PVT(0.01)ELAS(0.045)RS(0.955)PIR 84.89200000000001 0.019194 14197000.0 44272.0 42007.0 60010.0 69778.0 67998.0 60860.0 50400.0 68338.0 58220.0 56877.0 True False 58349.57508519412 55584.94125834284 59214.22819016253 53691.7601593533 58557.65143091742 57054.41457907002 54885.5023622627 57777.93235101605 61297.39034151433 54885.753542011444 1.063109665434972 1.0127389654183434 1.0788633546743223 0.9782458414870041 1.0669007465861862 1.0395122759023179 0.9999954235893189 1.052694526764415 1.1168178695878739 1.0 15.744144103251244 -7.995407816446927 24.938837755884105 1.067191358705487 1.0338232112596677 0.05498824300602079 0.03958279633380948 245.13665131123147 1331269.8149148447 0.02017970072357304 0.009634706296094388 1.0106299945659269e-08 7.995407816446927 -0.033368147445819396 SSS(ph)PVTELASRS(ph)PIRQDR ddPTM_PC-9_AZD4547_30min_R2 1 SSSPVTELASRSPIRQDR 18 2 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 S(0.024)S(0.041)S(0.685)PVT(0.213)ELAS(0.149)RS(0.888)PIRQDR 133.94 0.0010532 6993900.0 20403.0 14925.0 25798.0 47646.0 42890.0 29636.0 18650.0 33033.0 19445.0 26974.0 True False 26890.729591236344 19749.214375717544 25455.90166388624 36661.95082336195 36935.46383528996 27782.856235052892 20309.81387016268 27928.508872824976 20472.823002245706 26029.648470246604 1.033080781785202 0.7587199803444153 0.9779579502575231 1.4084689182517651 1.4189766672227375 1.0673542620758134 0.780256940211005 1.0729499057487804 0.7865193809915385 1.0 14.66786820786249 -7.018448497748623 24.173949235476364 0.9171242247418143 1.1211545058715682 0.1990072721602376 0.1994514845353342 970.1012859256072 1271167.3415060388 0.08484726444423198 0.06703402466543813 9.58410365839075e-08 7.018448497748623 0.20403028112975385 SSS(ph)QENLLDEVMK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSQENLLDEVMK 13 0 A0A2R8Y4C6;A0A2R8YCU9;A0A2U3TZV9;A0A2R8Y7B1;H7C2C6;A0A2R8Y820;A0A2R8Y4Z5;A0A2R8Y885;A0A2R8Y7D4;A0A2R8YDS8;H0Y470;H0Y7U8;A0A2R8Y5D7;H0Y7K3;Q3V6T2-5;Q3V6T2-4;Q3V6T2-2;Q3V6T2-3;Q3V6T2 A0A2R8Y4C6 CCDC88A Girdin 1 S(0.001)S(0.004)S(0.995)QENLLDEVMK;S(0.012)S(0.012)S(0.976)QENLLDEVMK 176.42 0.00015205 2745100.0 23780.9 23901.9 22747.9 25750.2 28243.0 24699.3 23340.4 22583.9 24071.1 22473.4 True False 23441.780005117052 23846.55661907835 20877.655471433336 27643.95560814904 26581.80226787441 23642.968515880468 24548.851706545687 23633.230440580355 21359.95923807974 26357.897246076816 0.8893645720773948 0.9047215108416032 0.7920834987905124 1.0487921456732914 1.0084947983409762 0.8969975220386578 0.9313660902976473 0.8966280663415968 0.8103817629556552 1.0 14.6859476606063 -5.7418692597399845 24.999701091759572 0.9379778680687393 0.8663230918159341 0.2145233998722199 0.06951961576359558 452.97370118017704 578643.1459162743 0.019878691697233136 0.03436673179715655 1.8118854615653412e-06 5.7418692597399845 -0.07165477625280514 SSS(ph)QGPLSSIR ddPTM_PC-9_AZD4547_30min_R2 2 SSSQGPLSSIR 11 0 A0A0U1RQE4 A0A0U1RQE4 1 S(0.014)S(0.307)S(0.679)QGPLSSIR;SS(0.001)S(0.999)QGPLSSIR 103.11 0.0030413 23522000.0 64132.0 63380.0 69032.0 95387.0 74892.0 94382.0 87246.0 89698.0 70055.0 81465.0 True False 84524.64197153207 83866.34553654789 68116.59057529249 73397.00086445922 64494.53853001952 88480.27861981251 95010.72498210266 75837.23515498616 73757.96427988297 78612.93514601605 1.0752001793920503 1.0668262847682015 0.8664806936513997 0.9336504320584299 0.8204061890098244 1.1255180646221745 1.2085889530219076 0.9646915614348416 0.9382420862786075 1.0 16.262479095794482 -6.786079219023441 24.9999636670032 1.0552751266407199 0.9530359172366096 0.1722025038064371 0.10330891974764539 437.399055497402 443788.4849646336 0.03958987073425782 0.03493038021257233 1.6365179793410065e-07 6.786079219023441 -0.10223920940411024 SSS(ph)QGPLSSIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSQGPLSSIR 11 0 A0A0U1RQE4 A0A0U1RQE4 1 S(0.001)S(0.018)S(0.981)QGPLSSIR 86.699 0.010776 9523700.0 39884.0 52556.0 53659.0 52077.0 66467.0 47376.0 47182.0 49297.0 51958.0 34445.0 True False 46635.57345509266 57773.41234949623 54938.43406289073 49159.29452591197 53443.26848735182 44891.519159318515 42712.579391901236 48003.00598448903 52717.78745512128 40689.60583353005 1.1461298899254233 1.4198567709370231 1.3501834912743003 1.2081536185686645 1.3134378520647203 1.1032674866151173 1.0497172070589136 1.1797363233470404 1.295608211856392 1.0 15.31237268442001 -6.759414896607775 24.999869522564634 1.132152564153556 1.2939710586424618 0.3880052747871632 0.10133304793018227 59.275416135510376 731980.8191589365 0.03458071648531968 0.032939275730543095 1.7401436593573555e-07 6.759414896607775 0.16181849448890584 SSS(ph)QGPLSSIR ddPTM_PC-9_Lapatinib_30min_R1 4 SSSQGPLSSIR 11 0 A0A0U1RQE4 A0A0U1RQE4 1 SS(0.009)S(0.99)QGPLSSIR;SS(0.001)S(0.998)QGPLSSIR;S(0.013)S(0.281)S(0.706)QGPLSSIR;S(0.004)S(0.067)S(0.929)QGPLSSIR 130.15 0.00022343 47983000.0 360202.0 336929.0 294377.0 298635.0 310338.0 297262.0 241450.0 262942.0 269097.0 231429.0 True False 355065.453427044 336148.86160135595 270174.45938808186 320597.6141171562 292084.5289879832 284548.7972115669 253951.09957607687 275159.2452369642 238788.46214296567 271431.19429024187 1.308123240423766 1.238431207143831 0.9953699687854736 1.1811376911024478 1.0760904978211778 1.0483275437652841 0.9356002733588775 1.0137347918188648 0.8797384647235083 1.0 18.050227006769475 -1.5228787452990005 0.2990785636864297 0.9442399702829243 4.115404200445094 0.7146464320309416 0.06877790645285023 28.90898348197195 0.41185078099736994 0.07046166148911692 48.994774527509485 0.02999999999871081 1.5228787452990005 3.17116423016217 SSS(ph)QIPEGFGLTSGGSNYSLAR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSQIPEGFGLTSGGSNYSLAR 22 0 A2RRE0;Q9Y4E6-2;Q9Y4E6 A2RRE0 WDR7 WD repeat-containing protein 7 1 S(0.138)S(0.138)S(0.723)QIPEGFGLTSGGSNYSLAR 119.62 0.000136 0.0 4764.7 4491.1 6605.8 6096.4 7670.3 5170.5 4712.0 4896.2 8287.3 7084.7 True False 4696.754504261035 4480.701133882365 6062.696623125401 6544.749592994227 7219.148034390012 4949.36976802419 4955.964304006927 5123.695326456877 7353.897004862181 8309.280955230643 0.5652419901994596 0.5392405381432903 0.7296295137678513 0.7876433145366624 0.8688053843991882 0.5956435694846245 0.596437204459572 0.6166231896673974 0.8850220668291336 1.0 13.020507923245459 -14.522878745280329 0.18027415771031424 2.308535845944834 0.619483188912362 0.45134405674566247 0.1124474884309054 143.96147325954797 1.38244785851958 67.24121617876568 0.3860780880127499 3.0000000000000626e-15 14.522878745280329 -1.6890526570324722 SSS(ph)QPPGR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSQPPGR 8 0 P27987-2;P27987 P27987-2 ITPKB Inositol-trisphosphate 3-kinase B 1 S(0.051)S(0.191)S(0.758)QPPGR 82.26100000000001 0.039891 0.0 3701.9 6172.2 6577.0 5282.0 7521.9 4775.7 11080.0 11381.0 8880.8 6387.5 True False 3649.1102271546856 6157.908650118837 6036.26444795419 5670.45590023547 7079.476630624387 4571.45444370044 11653.668185143628 11909.802808383176 7880.550785030116 7491.5708641912515 0.4870954694691556 0.8219782955738764 0.8057408195665291 0.7569114679725613 0.9449922798519305 0.6102130683367631 1.5555707069189812 1.589760415310293 1.051922344177259 1.0 12.87105254545034 -7.257778007087068 24.99872508505974 1.34846007535505 0.75501894793557 0.6253932060498024 0.21127737260751073 195.547514338896 1335144.379269557 0.0809737125903671 0.06023864561090252 5.5235970998047026e-08 7.257778007087068 -0.59344112741948 SSS(ph)QPSPSDPK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSQPSPSDPK 11 0 A0A0A0MT50;A0A087X1S4;A0A087WUP2;E7ESE9;J3KNW2;E7EUP4;B5MDK9;Q9H322;Q9NNX9;Q9H320;Q9H321-2;Q9H321 A0A0A0MT50 VCX3B;VCX;VCX3A;VCX2 Variable charge X-linked protein 2;Variable charge X-linked protein 3;Variable charge X-linked protein 1;Variable charge X-linked protein 3B 1 S(0.113)S(0.028)S(0.619)QPS(0.232)PS(0.007)DPK 99.68799999999999 0.0044585 1897900.0 21150.0 21451.0 22284.0 27754.0 26920.0 21003.0 21602.0 22394.0 23583.0 18256.0 True False 20848.397121565027 21401.331527445513 20451.895538727567 29795.121744629898 25336.618526756352 20104.750650384318 22720.445860602234 23434.506993316314 20926.834200000594 21411.525275409058 0.9736997646547498 0.9995239130406439 0.955181626514781 1.3915459716851337 1.1833168445900129 0.9389686344986568 1.0611315900365332 1.0944809719011765 0.9773630757653157 1.0 14.386099951026674 -8.133278677412623 1.0739418287484221 0.9908785489654638 1.0827169313483698 0.05165582781947009 0.12824563020650473 1.8463626373411337 4.09210833284423 0.12992854049764826 0.0449907989000247 7.35734840795755e-09 8.133278677412623 0.09183838238290598 SSS(ph)S(ph)RMT(ph)SAPSQPLQT(ph)IS(ph)RNK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSSRMTSAPSQPLQTISRNK 21 2 Q5T670;Q7L590-2;Q7L590 Q5T670 MCM10 Protein MCM10 homolog 5 S(0.379)S(0.408)S(0.433)S(0.76)RMT(0.51)S(0.51)APS(0.129)QPLQT(0.939)IS(0.933)RNK 49.18600000000001 0.017723 9004200.0 3164.1 2911.3 8294.3 3294.0 5059.6 4050.7 4260.6 4316.7 7318.2 3732.8 True False 3118.9793537751225 2904.559063719738 7612.3746709238885 3536.251748461876 4762.004275556328 3877.461003642894 4481.193020724092 4517.269640888116 6493.947251937595 4378.009506356649 0.7124195023438213 0.6634428407481676 1.7387752721576106 0.8077304864978976 1.087709898446346 0.8856675614826821 1.0235685907528584 1.0318090068852679 1.483310450219149 1.0 12.09605937183483 -8.036350011251246 22.791683389356912 1.2469572674124778 0.9998801557894685 0.09735995269331277 0.30280053235641513 503.22897052268837 315521.13612828346 0.20114853530836715 0.07612395168782556 9.197080520420416e-09 8.036350011251246 -0.24707711162300927 SSS(ph)SDSIHSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSSDSIHSVR 11 0 Q8WYL5-4;Q8WYL5 Q8WYL5-4 SSH1 Protein phosphatase Slingshot homolog 1 1 S(0.001)S(0.002)S(0.948)S(0.037)DS(0.012)IHSVR;S(0.015)S(0.003)S(0.93)S(0.045)DS(0.008)IHSVR 152.96 0.00035429 65784000.0 60724.0 53351.0 176247.0 162622.0 178279.0 189030.0 108908.0 133183.0 163201.0 103957.0 True False 71003.37384633049 58647.33469552432 180449.3969004698 153510.8165676372 143346.50973650988 179116.93403170325 98591.44581436102 129687.08736905298 165587.50587904168 122803.58117684066 0.5781865086172333 0.47757023153152584 1.4694147774128632 1.25005162794542 1.1672828134391848 1.4585644190112808 0.8028385236777952 1.0560529760308852 1.3483931355437506 1.0 16.90599310738216 -5.249070690335217 24.92724089309762 1.1925923274664858 0.52787825197826 0.6464871231319864 0.19705141396211606 448.27981971485474 903436.786496197 0.0508604523478365 0.13251450001000145 5.635459197022531e-06 5.249070690335217 -0.6647140754882258 SSS(ph)SERPEPQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSERPEPQQK 12 1 P78362;C9J2M4 P78362 SRPK2 SRSF protein kinase 2;SRSF protein kinase 2 N-terminal;SRSF protein kinase 2 C-terminal 1 S(0.031)S(0.136)S(0.831)S(0.003)ERPEPQQK 89.43 0.044412 0.0 10991.0 9690.2 9379.3 9363.8 9314.4 9973.5 10326.0 11733.0 9574.2 8567.5 True False 12851.559217854858 10652.179015699236 9602.93808319333 8839.176643849201 7489.310183979863 9450.472102656695 9347.846526233996 11425.021182141103 9714.20456239312 10120.719929707311 1.2698265841871312 1.0525119842939172 0.9488394254450083 0.873374296022519 0.7399977705139847 0.9337746887863935 0.9236345429138195 1.1288743549364786 0.9598333547279628 1.0 13.305024298245334 -4.810231930045814 2.042389501992035 0.9327444186821782 1.353488238179342 0.5477794997579049 0.09205485517055505 0.5645987046184919 2.7599698924373697 0.027543981943876125 0.4397857864523293 1.5479897117711175e-05 4.810231930045814 0.4207438194971639 SSS(ph)SFTPFIDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSSFTPFIDPR 12 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6;E7EN19 C9J840;O95819-6;E7EN19 MAP4K4 1 S(0.037)S(0.088)S(0.838)S(0.036)FTPFIDPR;S(0.002)S(0.002)S(0.498)S(0.498)FTPFIDPR 157.38 0.00041909 4964900.0 36965.1 40045.0 44995.3 44211.6 45726.7 46808.4 43592.8 40923.8 41259.7 31300.5 True False 43222.561335995495 44020.402951814795 46068.15859762549 41734.567387941126 36766.8813868625 44353.68510252124 39463.37439945897 39849.593612350276 41863.04505681642 36975.032875378325 1.1689661367354023 1.190543984103608 1.2459261024295742 1.1287229284854043 0.9943704853700229 1.199557692132746 1.0672978853722028 1.0777432909028222 1.1321976426069122 1.0 15.174263809608727 -1.5228788111755445 0.0977428204221095 0.9429806872795835 1.7022374105848785 0.4037184589534797 0.06203014663890739 140.03599566581477 0.9770332157334755 0.8920344510572961 14.24850856684596 0.029999995448120712 1.5228788111755445 0.759256723305295 SSS(ph)SGSDDYAYTQALLLHQR ddPTM_PC-9_AZD4547_30min_R2 2 SSSSGSDDYAYTQALLLHQR 20 0 F6SS63;Q8N5C8-2;Q8N5C8 F6SS63 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 1 S(0.083)S(0.083)S(0.559)S(0.115)GS(0.161)DDYAYTQALLLHQR;S(0.083)S(0.083)S(0.588)S(0.123)GS(0.123)DDYAYTQALLLHQR 198.47 6.730900000000001e-16 54460000.0 28270.3 32683.0 54493.0 78310.0 54882.0 57376.0 51047.0 80824.0 61758.0 57462.0 True False 37259.66734123063 43247.14059910059 53770.38721490634 60256.83937743924 47262.581632277535 53788.269649831105 55590.084108857605 68334.50795075229 65022.40179854417 55450.27287007156 0.6719474118465695 0.7799265605136918 0.9697046458346301 1.0866824680670228 0.852341732258396 0.9700271408197615 1.002521380537002 1.2323565676740753 1.1726254612110127 1.0 15.758906939437434 -3.988144908944796 0.42834386735773056 1.1005440838547649 5.7205837876736276e-15 0.6310784629894346 0.09871182854603651 7.323596985029942 0.6243981351296676 0.07802157229084472 4.7172463321690525 0.0001027673342106718 3.988144908944796 -1.100544083854759 SSS(ph)SGSDDYAYTQALLLHQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSSSGSDDYAYTQALLLHQR 20 0 F6SS63;Q8N5C8-2;Q8N5C8 F6SS63 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 1 S(0.033)S(0.033)S(0.309)S(0.309)GS(0.309)DDY(0.007)AYTQALLLHQR;S(0.079)S(0.079)S(0.534)S(0.117)GS(0.142)DDY(0.049)AY(0.001)TQALLLHQR;S(0.094)S(0.094)S(0.635)S(0.136)GS(0.043)DDYAYTQALLLHQR;S(0.106)S(0.106)S(0.589)S(0.139)GS(0.057)DDY(0.002)AYTQALLLHQR 181.51 3.2892999999999997e-10 32120300.0 47706.1 50699.2 61490.8 77473.7 85814.0 97389.0 82163.0 102440.0 85217.5 66117.7 True False 55781.80049157549 55732.28151665998 62956.973877157616 73133.0997621244 68999.36272095333 92281.74939646384 74379.92583139286 99751.05854415195 86463.64472182911 78104.31562257493 0.7141961368835368 0.7135621261439153 0.8060626788074795 0.9363515854300161 0.883425738654191 1.1815192113378064 0.9523151856399393 1.2771516880857265 1.1070277491406384 1.0 16.253114645653874 -6.084370217005553 0.8085238621244359 1.1255068257835508 0.6844227566717972 0.7115950435567573 0.09668427013670482 0.3625518668870577 0.48750363117350504 0.047273527935889126 0.10154474087180726 8.234358727595781e-07 6.084370217005553 -0.4410840691117536 SSS(ph)SGSDDYAYTQALLLHQR ddPTM_PC-9_Lapatinib_30min_R1 3 SSSSGSDDYAYTQALLLHQR 20 0 F6SS63;Q8N5C8-2;Q8N5C8 F6SS63 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 1 S(0.097)S(0.097)S(0.549)S(0.119)GS(0.119)DDY(0.019)AYTQALLLHQR;S(0.076)S(0.076)S(0.608)S(0.102)GS(0.137)DDYAYTQALLLHQR;S(0.072)S(0.072)S(0.4)S(0.194)GS(0.26)DDY(0.001)AYTQALLLHQR 172.69 3.681e-09 41902000.0 32105.5 25850.1 38336.0 24038.8 42036.5 40438.2 50271.9 34602.4 41066.9 45804.5 True False 31647.669682572385 25790.245681675395 35184.16206123943 25806.693543086 39563.9957169388 38708.752452048335 52874.73299970414 36210.15382627168 36441.51326837147 53721.74679434022 0.5891035115393266 0.4800708692590854 0.6549333214337366 0.4803770369172885 0.7364614532807225 0.720541582540768 0.984233316204727 0.6740315791460182 0.6783382045985652 1.0 15.713218595159193 -6.47892928736098 2.59205227925698 0.8026344383520204 0.5532099595685733 0.5247512667943712 0.11630264965573742 0.24284809269437613 3.245616747938264 0.039606270755036935 0.04357026376166105 3.319485016279909e-07 6.47892928736098 -0.2494244787834471 SSS(ph)SGSLNAR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSSGSLNAR 10 0 H0Y7V5;Q7Z3E2 H0Y7V5 CCDC186 Coiled-coil domain-containing protein 186 1 S(0.032)S(0.139)S(0.444)S(0.313)GS(0.072)LNAR 70.72800000000001 0.035018 5788000.0 10810.0 11843.0 16771.0 14360.0 14879.0 15777.0 18030.0 16195.0 19178.0 15102.0 True False 10655.847417688794 11815.578261131745 15392.153117932145 15416.082303555711 14003.846473239513 15102.254487983306 18963.505178532454 16947.47882275421 17017.97168670701 17712.360577849904 0.6016051542567626 0.6670809466191453 0.8690063106089155 0.8703572985542203 0.7906256431314946 0.8526392866498748 1.070636807284014 0.9568164981887161 0.9607963665774025 1.0 14.11246887662013 -3.9639129211514668 0.35078954966185494 1.0029246392091642 1.4066326257653056e-17 0.7929537378651388 0.06311318390039618 5.567199214844777 0.3515555612386662 0.06259669979185382 2.6398626382377284 0.00010866434808114899 3.9639129211514668 -1.0029246392091642 SSS(ph)SPELQTLQDILGDPGDKADVGR ddPTM_PC-9_AZD4547_30min_R2 2 SSSSPELQTLQDILGDPGDKADVGR 25 1 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4;A0A2R8Y670 P49815 TSC2 Tuberin 1 S(0.166)S(0.166)S(0.501)S(0.166)PELQT(0.002)LQDILGDPGDKADVGR;S(0.137)S(0.137)S(0.69)S(0.036)PELQTLQDILGDPGDKADVGR 146.6 6.4685e-07 76440000.0 62100.0 66004.6 91076.0 143062.0 105392.0 97247.0 90650.0 100809.0 81925.0 94890.0 True False 81846.5082397578 87339.29615969751 89868.27273199885 110081.26618586661 90760.13999834177 91166.12971690473 98717.67438768077 85231.28541036558 86255.38824679762 91567.92998226837 0.8938337718850576 0.9538197071464899 0.9814382912161643 1.2021814428608713 0.9911782434736373 0.9956119979403112 1.0780813152246307 0.9307984293941138 0.9419825070141971 1.0 16.48255478838768 -5.122502605928064 2.613867775088011 1.02045564776426 0.9027984649611285 0.21858449154175197 0.07336363175538091 0.4792109944237004 5.966086070744486 0.020581693777047626 0.08668018217391144 7.542188702408707e-06 5.122502605928064 -0.11765718280313142 SSS(ph)SPELQTLQDILGDPGDKADVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSSPELQTLQDILGDPGDKADVGR 25 1 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4;A0A2R8Y670 P49815 TSC2 Tuberin 1 S(0.047)S(0.047)S(0.705)S(0.202)PELQTLQDILGDPGDKADVGR;S(0.15)S(0.15)S(0.582)S(0.118)PELQTLQDILGDPGDKADVGR 140.64 9.6706e-10 28546000.0 66293.0 62175.0 57301.0 80738.0 95029.0 78159.0 90604.0 74680.0 82506.0 77534.0 True False 77515.09555356677 68347.32309973992 58667.27315525265 76214.51161612786 76408.74962138438 74060.20444894416 82021.33320384512 72719.72913000068 83712.49416398311 91590.30044119351 0.8463242852155085 0.7462288339541262 0.6405402414082109 0.8321242669693192 0.8342449937746782 0.8086031391118241 0.8955242291896155 0.7939675793147019 0.913988640289826 1.0 16.482907202256712 -8.360804551458255 0.30740450890121385 1.025011085328279 0.7383105539926229 0.5559047223253893 0.06150882136595673 1.3754600251893037 0.4234800384284189 0.14546654752427496 0.09611894659835954 4.357079142079614e-09 8.360804551458255 -0.2867005313356561 SSS(ph)SPELQTLQDILGDPGDKADVGR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSSPELQTLQDILGDPGDKADVGR 25 1 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4;A0A2R8Y670 P49815 TSC2 Tuberin 1 S(0.162)S(0.162)S(0.622)S(0.052)PELQT(0.001)LQDILGDPGDKADVGR 86.07600000000001 4.5412e-06 35366000.0 11654.0 7977.1 8647.6 8208.4 8905.6 9292.4 7229.9 6930.6 12408.0 5426.2 True False 11487.811822918147 7958.629515061562 7936.627708701334 8812.073118419685 8381.790117083256 8894.98571364239 7604.228845827612 7252.620977399218 11010.480377967488 6364.111440042984 1.8050928132145587 1.2505484214160474 1.24709125279675 1.3846509762500587 1.317040123519057 1.3976791257417567 1.19486104501279 1.1396125045463115 1.7300891855365 1.0 12.635743383151558 -4.757867414279168 24.984510880150502 1.3020516355796807 1.8050935284068488 0.41094612918848417 0.18280941508134715 98.38660296681748 688071.1300245052 0.04245453294723312 0.3040908314708496 1.7463552161638205e-05 4.757867414279168 0.503041892827168 SSS(ph)SQTLTQFDSNIAPADPDTAIVHPVPIR ddPTM_PC-9_AZD4547_30min_R2 1 SSSSQTLTQFDSNIAPADPDTAIVHPVPIR 30 0 Q96D71;Q96D71-3;H0YE73 Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 S(0.156)S(0.156)S(0.256)S(0.256)QT(0.176)LTQFDSNIAPADPDTAIVHPVPIR 182.17 1.015e-23 9370200.0 953.66 3038.2 4963.4 8258.4 5965.2 4964.6 4962.0 6485.9 6009.6 5944.0 True False 1256.9040426397312 4020.23873476081 4897.582072972049 6354.553471008103 5137.034946847093 4654.162777181251 5403.608387332294 5483.653186154922 6327.255187158441 5735.9023692127885 0.21912926018164292 0.7008903701602855 0.8538468331085292 1.1078559330291076 0.8955931632344214 0.8114089950627945 0.9420677060920583 0.956022755127109 1.1030967369876645 1.0 12.48580475280036 -4.795554445360671 1.7370737531751508 0.9587964061350903 2.9013259069262714e-17 0.8694786862467371 0.08818208370399594 0.3145811428291588 0.9798834472871187 0.025588385259664236 0.5024927384645796 1.601199901214188e-05 4.795554445360671 -0.9587964061350903 down SSS(ph)SQTLTQFDSNIAPADPDTAIVHPVPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSQTLTQFDSNIAPADPDTAIVHPVPIR 30 0 Q96D71;Q96D71-3;H0YE73 Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 S(0.299)S(0.075)S(0.498)S(0.124)QT(0.004)LTQFDSNIAPADPDTAIVHPVPIR 192.05 8.545099999999999e-30 7541900.0 939.58 3300.8 6900.4 8132.8 8069.8 4317.2 6814.3 9112.6 4977.6 5997.7 True False 1098.6323364491018 3628.481609772762 7064.931705912732 7677.145582893352 6488.580619544011 4090.798432003757 6168.800172740295 8873.403905597796 5050.387983305973 7085.03553223292 0.15506377229174698 0.5121331563215478 0.9971624946369391 1.0835719239468407 0.9158148311359379 0.5773857327028113 0.8706802026151782 1.2524148771348862 0.7128246513838291 1.0 12.790559373097926 -5.010259279294109 2.8237467696333725 0.9253993086739677 0.15616825861638925 0.6606334242631695 0.17839283003041834 0.1816249319316761 2.6659374704815395 0.048949932658117756 0.2532318462264734 9.766539721058184e-06 5.010259279294109 -0.7692310500575784 SSS(ph)SQTLTQFDSNIAPADPDTAIVHPVPIR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSSQTLTQFDSNIAPADPDTAIVHPVPIR 30 0 Q96D71;Q96D71-3;H0YE73 Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 S(0.184)S(0.236)S(0.388)S(0.109)QT(0.083)LTQFDSNIAPADPDTAIVHPVPIR;S(0.313)S(0.075)S(0.492)S(0.117)QT(0.003)LTQFDSNIAPADPDTAIVHPVPIR 171.45 5.220300000000001e-19 11951600.0 9088.2 10854.0 11925.2 9878.8 11281.3 11676.0 11974.8 7389.1 13463.76 11453.5 True False 8958.600601428241 10828.868229867767 10944.756088603204 10605.319906710742 10617.756113889161 11176.644698085385 12594.796550853604 7732.424561235758 11947.329569121826 13433.222214170566 0.6668988615388128 0.8061258912582051 0.8147528503665855 0.7894844392228768 0.7904102191273663 0.8320151725246724 0.9375856626243765 0.5756194930713574 0.8893867293074861 1.0 13.713517783705994 -8.523648280013353 24.987665270845007 1.000000015447037 0.7835643189213356 0.3761166395810974 0.09191604989831147 74.29876323981865 2412596.7790773525 0.08542086181316733 0.022055571738964178 2.994688949151744e-09 8.523648280013353 -0.21643569652570138 SSS(ph)SRGSSYSSIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSRGSSYSSIPK 14 1 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 1 S(0.176)S(0.176)S(0.564)S(0.035)RGS(0.039)S(0.01)YS(0.001)SIPK 60.364 0.026467 3454700.0 22242.0 27101.0 20422.0 28238.0 33194.0 32391.0 32103.0 32177.0 26215.0 17240.0 True False 26007.131300475634 29791.408175730598 20908.937930866283 26655.91640883122 26689.873985122787 30692.358938903366 29061.971434407315 31332.38784434962 26598.344781092495 20365.475528235092 1.2770205765349716 1.4628388192766335 1.026685475714904 1.3088776823244288 1.3105450912805559 1.5070779416051876 1.4270214998964905 1.5385050941192013 1.306050759493243 1.0 14.313837880815258 -6.53700927665489 23.463711957084964 1.3955064685132665 1.270950885563967 0.029108412941819983 0.17212772608376947 264.5666551993299 439306.0519635298 0.05447529454099108 0.054506761626653986 2.903960624368824e-07 6.53700927665489 -0.12455558294929947 SSS(ph)SS(ph)S(ph)S(ph)S(ph)GSPSPSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSSSSSSGSPSPSR 15 0 H3BMS0;H3BMM9;H3BTC0;Q15287-3;Q15287-2;Q15287;H3BUG0;H3BTY0;H3BUL0 H3BMS0 RNPS1 RNA-binding protein with serine-rich domain 1 5 S(0.016)S(0.017)S(0.938)S(0.455)S(0.821)S(0.897)S(0.776)S(0.742)GS(0.272)PS(0.036)PS(0.029)R 54.073 0.041533999999999995 0.0 2561.6 2868.2 4342.4 2800.2 5361.3 3511.6 3958.2 3713.4 4581.9 3785.5 True False 2525.071114260093 2861.558859121683 3985.3846341487388 3006.1360491933633 5045.958874721352 3361.417053939415 4163.136228378655 3885.9381204331867 4065.8381724540013 4439.818631138312 0.5687329425014592 0.6445215665010208 0.897645819628208 0.6770853268892717 1.136523649712158 0.7571068399876485 0.937681597887993 0.8752470412145827 0.9157667261312368 1.0 12.116285027610953 -4.860015419924979 0.8411089848060594 0.9158576727072262 0.37075214530887973 0.5127505096738456 0.11650526222790457 1.743141680939922 1.0306881899953633 0.04095140300250761 0.8664722776769066 1.3803352539780278e-05 4.860015419924979 -0.5451055273983465 SSS(ph)SS(ph)SSSSGSEASSEHKR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSSSSSSSGSEASSEHKR 19 1 A0A1B0GV45 A0A1B0GV45 2 S(0.053)S(0.077)S(0.868)S(0.004)S(0.592)S(0.402)S(0.004)SSGSEASSEHKR 142.19 4.4675e-09 0.0 406.34 0.0 0.0 569.07 513.05 0.0 376.57 0.0 0.0 0.0 True False 400.54551708637007 0.0 0.0 610.9213061618701 482.87340769510917 0.0 396.06695202883907 0.0 0.0 0.0 0.0 SSS(ph)SSASPS(ph)SPSSR ddPTM_PC-9_AZD4547_30min_R2 1 SSSSSASPSSPSSR 14 0 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 S(0.101)S(0.151)S(0.741)S(0.007)S(0.011)AS(0.036)PS(0.565)S(0.375)PS(0.012)S(0.002)R 134.02 0.00021106 1659600.0 4110.5 5705.1 6546.0 6667.4 7954.0 7419.8 5920.9 7516.6 6151.5 5502.4 True False 5417.553496288632 7549.16200568886 6459.195762919579 5130.333940303136 6849.724396033955 6955.8387330559235 6447.848629696845 6355.08218428469 6476.655731463851 5309.762650800216 1.0203005016565423 1.421751310211795 1.2164754222952199 0.9662077719293086 1.2900245917774982 1.310009352679377 1.2143383901962383 1.1968674688927834 1.2197636989457104 1.0 12.374431657901194 -10.586435033468419 4.354320920367909 0.9999826175966423 1.211261465695995 0.19491327049286855 0.12533725719012714 43832229.32343189 0.7268889097548777 7765.58497750106 0.029927433104768794 2.5915820696278748e-11 10.586435033468419 0.2112788480993527 SSS(ph)SSASPSS(ph)PSSR ddPTM_PC-9_AZD4547_30min_R2 1 SSSSSASPSSPSSR 14 0 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 S(0.043)S(0.06)S(0.563)S(0.079)S(0.251)AS(0.01)PS(0.228)S(0.735)PS(0.028)S(0.004)R 113.43 0.0025374000000000004 2999200.0 5698.8 6167.8 9374.8 10470.0 8538.1 9862.7 7960.4 9032.7 7047.4 8049.1 True False 7510.899857596316 8161.420732097196 9250.484026614497 8056.303259887492 7352.732193333865 9245.983809875015 8668.860178661824 7636.903765796817 7419.911176447752 7767.303458955369 0.9669893673249716 1.0507405530406344 1.1909517988445635 1.0372072241620633 0.9466261016049887 1.1903724193001357 1.1160707476501384 0.983211716415147 0.9552750469524802 1.0 12.9231981160362 -7.821906287813796 8.601235759412647 0.9761573491676447 1.0735122878318122 0.22833384214189734 0.07719354286712364 0.4555518835196077 58.675575746427086 0.04396938903642183 0.0211097333027104 1.5069321973630178e-08 7.821906287813796 0.09735493866416745 SSS(ph)SSASPSS(ph)PSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSSASPSSPSSR 14 0 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 S(0.088)S(0.12)S(0.704)S(0.074)S(0.006)AS(0.012)PS(0.069)S(0.874)PS(0.046)S(0.007)R 93.71600000000001 0.044152 2676400.0 6862.1 7667.2 6503.9 8384.6 8661.9 8112.4 11550.0 9664.9 7468.7 7368.5 True False 8023.717997347089 8428.348945240466 6658.977642178105 7914.838045239966 6964.662874969421 7686.971462935991 10455.900385241386 9411.206615808016 7577.915608107785 8704.350720986096 0.9218054573561691 0.9682915148306016 0.7650171570090095 0.909296775709804 0.8001358284171263 0.8831183059297905 1.2012269174807402 1.0812071936758818 0.8705894156858262 1.0 13.087520972366326 -7.097610787285331 11.582048486472566 1.04492857497481 0.8709857822286399 0.42186834122204586 0.0937691543367851 0.6539253135531319 74.9775752298359 0.03615577975459398 0.028007563818375478 7.987101669887101e-08 7.097610787285331 -0.1739427927461702 SSS(ph)SSASPSS(ph)PSSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSSSASPSSPSSR 14 0 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 S(0.063)S(0.087)S(0.734)S(0.105)S(0.011)AS(0.014)PS(0.236)S(0.74)PS(0.009)S(0.001)R 107.13 0.0098149 1976200.0 5097.4 6448.5 6756.7 6304.5 7280.2 7421.7 7668.7 9470.9 7432.9 7304.7 True False 5024.710141251323 6433.568894444661 6201.190207616245 6768.1539611954795 6851.992949423904 7104.2911918277 8065.747762762722 9910.952589220302 6595.728530093054 8567.307662099072 0.5864981554800637 0.7509440711352223 0.7238201839125845 0.7899977715446275 0.79978369164171 0.8292326448431853 0.9414565323065026 1.1568339763337065 0.7698717952282617 1.0 13.064626182955925 -6.411221605560082 0.596278227913925 0.9938003977128618 0.6412753517973733 0.5797647370939121 0.0984953245334507 0.6649475081683237 0.5082850052142532 0.07259544824976563 0.12065493240042047 3.8795235671125293e-07 6.411221605560082 -0.3525250459154885 SSS(ph)SSASPSSPSSR ddPTM_PC-9_AZD4547_30min_R2 2 SSSSSASPSSPSSR 14 0 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 S(0.001)S(0.03)S(0.914)S(0.024)S(0.006)AS(0.001)PS(0.009)S(0.013)PSS(0.002)R;S(0.075)S(0.075)S(0.581)S(0.075)S(0.145)AS(0.046)PS(0.001)SPSSR 89.26 0.023190000000000002 0.0 11036.0 9002.3 13427.4 21850.0 17591.4 13044.3 11799.599999999999 15625.6 11201.099999999999 14225.0 True False 14545.21843693988 11912.117425428616 13249.3439026927 16812.820079134828 15149.13775966705 12228.63785891822 12849.741541145926 13211.02256056712 11793.16727850113 13726.987079753026 1.0596074981664203 0.8677882011704303 0.9652040776111142 1.224800459230659 1.1036025364962763 0.8908464609073004 0.9360933660452689 0.9624123985701902 0.859122778362323 1.0 13.744727384343072 -6.769847862333447 24.999006854568194 0.9277456670788724 1.0400445059380026 0.2744127927708021 0.09294797031807975 293.83736738432975 873593.7782101514 0.035690779080284216 0.031986725729534045 1.698838668278911e-07 6.769847862333447 0.11229883885913017 SSS(ph)SSASPSSPSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSSASPSSPSSR 14 0 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 S(0.001)S(0.011)S(0.952)S(0.034)S(0.002)ASPSSPSSR 94.781 0.015038 0.0 4974.5 5287.0 9227.3 11127.0 10542.0 8005.7 6999.3 8220.7 11524.0 7456.0 True False 5816.584599146483 5811.858419434257 9447.313826730118 10503.590264220731 8476.370776380198 7585.866998770611 6336.275633456283 8004.915335551635 11692.516698733925 8807.713778336472 0.660396641572641 0.6598600460574857 1.0726181690834244 1.1925444591598164 0.9623803622262057 0.8612753762989975 0.7194007199735577 0.9088528007393465 1.3275314108745153 1.0 13.104551871493078 -5.252642818382474 24.35802469978525 0.992080843453082 0.6601282620261923 0.42292805956251867 0.16079036724916868 476.1391408807456 1318436.8149312534 0.04431981549598624 0.11336590417973072 5.5892969248925104e-06 5.252642818382474 -0.33195258142688966 SSS(ph)TEPPPPVR ddPTM_PC-9_AZD4547_30min_R2 2 SSSTEPPPPVR 11 0 Q8N684-2;Q8N684;Q8N684-3;F5H669;F5H6M0;F5H047;F5H5B7;F5H1W4;F5H2K8;F5H6P5;F5H6A8;F5GXA3;C9JM38;C9J286;C9J323;J3QT54 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 1 SS(0.001)S(0.988)T(0.01)EPPPPVR;S(0.001)S(0.004)S(0.954)T(0.041)EPPPPVR 124.67 0.00049986 13903700.0 40635.0 51283.0 67763.0 67794.0 67419.0 52986.0 47623.0 86114.0 59010.0 55267.0 True False 53556.08473949366 67859.2268562762 66864.41834444238 52165.14070685891 58059.0355866499 49672.77704381536 51861.35474202455 72807.06000285914 62129.148128697314 53332.1191519656 1.004199450370421 1.2723894706474494 1.2537363863963025 0.9781186560057462 1.0886317009308282 0.9313857734075176 0.9724225394878793 1.3651634542291722 1.1649480485046035 1.0 15.702717034202461 -5.750926111120045 24.996686414474745 1.077483909076164 1.1863365186323442 0.11003962057714545 0.1356153908748443 510.61482410381683 1214042.9888965536 0.039343864637780224 0.06723633956368544 1.7744913590660053e-06 5.750926111120045 0.10885260955618015 SSS(ph)TEPPPPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSSTEPPPPVR 11 0 Q8N684-2;Q8N684;Q8N684-3;F5H669;F5H6M0;F5H047;F5H5B7;F5H1W4;F5H2K8;F5H6P5;F5H6A8;F5GXA3;C9JM38;C9J286;C9J323;J3QT54 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 1 S(0.022)S(0.002)S(0.934)T(0.041)EPPPPVR;S(0.001)S(0.019)S(0.924)T(0.056)EPPPPVR;S(0.002)S(0.002)S(0.953)T(0.042)EPPPPVR 163.46 0.0009387 39459800.0 151388.0 196526.0 170199.0 153866.0 180480.0 136395.0 165250.0 127145.0 123072.0 110472.0 True False 177014.99835070636 216035.80248491335 174257.18964330218 145245.3868603028 145116.2395865206 129242.20609032513 149596.32369360526 123807.57847126336 124871.69517065103 130499.69910412913 1.3564398965354045 1.655450579334537 1.3353072140362392 1.1129940364414763 1.1120043998778 0.9903640159905609 1.1463346254479747 0.9487192638848465 0.9568734336392043 1.0 16.99368695478384 -5.700703958726468 2.2157449099081594 1.0303911450903915 1.510921780070885 0.8186154652117213 0.09131874382436517 0.11483510567271803 1.1450662363719677 0.026430935791057618 0.05318597960998823 1.9920307644189496e-06 5.700703958726468 0.4805306349804934 SSS(ph)TEPPPPVR ddPTM_PC-9_Lapatinib_30min_R1 4 SSSTEPPPPVR 11 0 Q8N684-2;Q8N684;Q8N684-3;F5H669;F5H6M0;F5H047;F5H5B7;F5H1W4;F5H2K8;F5H6P5;F5H6A8;F5GXA3;C9JM38;C9J286;C9J323;J3QT54 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 1 SS(0.005)S(0.948)T(0.047)EPPPPVR;SS(0.004)S(0.947)T(0.049)EPPPPVR;S(0.001)S(0.019)S(0.972)T(0.008)EPPPPVR;S(0.003)S(0.001)S(0.996)TEPPPPVR 205.52 6.3654999999999994e-06 59753900.0 130511.0 157486.0 163120.0 143888.0 190611.0 162224.0 173113.0 154730.0 157918.0 154902.0 True False 128649.88920721371 157121.35084291117 149708.90326140894 154470.00351629665 179399.63573564444 155286.05768261425 182075.94409158546 161919.320669636 140131.61188973815 181676.60430605913 0.7081257914226828 0.864840860731956 0.8240406288594198 0.8502470866092959 0.9874669136451999 0.8547388821788722 1.002198080413555 0.89125025915203 0.771324477496658 1.0 17.471013120619617 -3.668181346767144 0.6992748539862009 0.9101170553228414 1.0998190006023655e-17 0.39509118760821105 0.07255882997467998 13.1551266811603 1.4965232059502718 0.028775252206534364 13.550211393960385 0.00021469337995953705 3.668181346767144 -0.9101170553228414 SSS(ph)TGNLLDKDDLAIPPPDYGAASR ddPTM_PC-9_AZD4547_30min_R2 7 SSSTGNLLDKDDLAIPPPDYGAASR 25 1 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 S(0.141)S(0.141)S(0.674)T(0.045)GNLLDKDDLAIPPPDYGAASR;S(0.147)S(0.147)S(0.583)T(0.124)GNLLDKDDLAIPPPDYGAASR;S(0.191)S(0.191)S(0.556)T(0.062)GNLLDKDDLAIPPPDYGAASR;S(0.174)S(0.2)S(0.563)T(0.064)GNLLDKDDLAIPPPDYGAASR;S(0.151)S(0.151)S(0.654)T(0.045)GNLLDKDDLAIPPPDYGAASR;S(0.266)S(0.266)S(0.368)T(0.1)GNLLDKDDLAIPPPDYGAASR;S(0.194)S(0.194)S(0.548)T(0.064)GNLLDKDDLAIPPPDYGAASR 123.03 8.7546e-10 124282900.0 393123.29999999993 424950.3 604018.9 757403.2999999999 732516.9 793693.0 725430.1 749894.0 766978.9 748369.0 True False 518128.33192738617 562307.1741189598 596009.2147270615 582795.6709493358 630819.572597079 744063.2512406484 789991.9735556832 634015.1131498264 807519.8388355426 722168.8290957953 0.7174615007630809 0.7786367279559917 0.8253045419771242 0.8070075132971826 0.8735070625893784 1.0303175950868255 1.0939159123564044 0.8779319843306678 1.1181870586225835 1.0 19.461976625158947 -6.556199777032521 2.3829137524258663 1.0219560775955299 0.783385049423635 0.7523594506079745 0.06567308908523026 0.1498050209430088 1.719795279215934 0.023232133411511504 0.024407441585550735 2.778434883655078e-07 6.556199777032521 -0.2385710281718949 SSS(ph)TGNLLDKDDLAIPPPDYGAASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 9 SSSTGNLLDKDDLAIPPPDYGAASR 25 1 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 S(0.176)S(0.176)S(0.543)T(0.105)GNLLDKDDLAIPPPDYGAASR;S(0.139)S(0.139)S(0.69)T(0.033)GNLLDKDDLAIPPPDYGAASR;S(0.161)S(0.161)S(0.626)T(0.051)GNLLDKDDLAIPPPDYGAASR;S(0.173)S(0.173)S(0.482)T(0.173)GNLLDKDDLAIPPPDYGAASR;S(0.149)S(0.149)S(0.693)T(0.009)GNLLDKDDLAIPPPDYGAASR;S(0.176)S(0.176)S(0.626)T(0.022)GNLLDKDDLAIPPPDYGAASR;S(0.141)S(0.141)S(0.684)T(0.035)GNLLDKDDLAIPPPDYGAASR;S(0.157)S(0.157)S(0.53)T(0.157)GNLLDKDDLAIPPPDYGAASR;S(0.131)S(0.131)S(0.595)T(0.144)GNLLDKDDLAIPPPDYGAASR 98.76 8.950200000000001e-07 147116000.0 345124.00000000006 449042.39999999997 577054.8999999999 754284.2 751010.4 743143.2000000001 719221.3999999999 668420.9 687218.3 551968.2 True False 403546.6766902867 493620.3618541644 590814.0773088943 712024.1016963692 603855.3032932644 704171.4623631648 651091.5422799872 650875.5596254847 697267.5675482068 652035.6652821333 0.6189027658719768 0.7570450331740317 0.9061069950111569 1.092001771694926 0.9261077812852132 1.079958505120226 0.9985520377911575 0.9982207941705972 1.069370288581533 1.0 19.314591354105453 -5.1832463691704875 1.7113626544869869 1.0216320456020653 0.6064309204209233 0.8805773627076399 0.04978585593590355 0.14173545308852997 0.6728861909079623 0.013445923174637883 0.07421532688498597 6.557731498511251e-06 5.1832463691704875 -0.41520112518114205 SSS(ph)TGNLLDKDDLAIPPPDYGAASR ddPTM_PC-9_Lapatinib_30min_R1 5 SSSTGNLLDKDDLAIPPPDYGAASR 25 1 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 S(0.15)S(0.15)S(0.691)T(0.009)GNLLDKDDLAIPPPDYGAASR;S(0.191)S(0.191)S(0.578)T(0.04)GNLLDKDDLAIPPPDYGAASR;S(0.194)S(0.194)S(0.593)T(0.019)GNLLDKDDLAIPPPDYGAASR;S(0.174)S(0.174)S(0.478)T(0.174)GNLLDKDDLAIPPPDYGAASR;S(0.126)S(0.126)S(0.636)T(0.112)GNLLDKDDLAIPPPDYGAASR 111.31 9.3496e-08 128968200.0 1106505.0 881932.0 894854.0 942050.0 959529.0 849199.0 664513.0 766985.0 842952.0 670892.0 True False 1090726.035791837 879889.9406397403 821282.558356334 1011331.4995866773 903091.3907265967 812880.7383495552 698918.2316529187 802621.923116402 748009.8690819197 786854.7882926028 1.386184658237392 1.1182367493105236 1.0437536513419916 1.2852835296092775 1.1477230667760387 1.0330759251188217 0.8882429668751236 1.0200381761138066 0.950632670997691 1.0 19.585737889661438 -6.80521677271682 3.0122970302355534 0.9659836459044769 1.1922643538574698 0.591050688655655 0.09232209863557816 0.19299159445016653 3.5796880633876493 0.03455241532908038 0.03131367161349502 1.5659692408344206e-07 6.80521677271682 0.22628070795299282 SSS(ph)TGSSSSTGGGGQESQPSPLALLAATCSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSTGSSSSTGGGGQESQPSPLALLAATCSR 31 0 P08047;H3BVI2;P08047-2 P08047 SP1 Transcription factor Sp1 1 S(0.122)S(0.122)S(0.494)T(0.151)GS(0.047)S(0.004)S(0.047)S(0.015)TGGGGQESQPSPLALLAATCSR 132.32 5.8649e-14 0.0 0.0 779.35 591.86 0.0 755.48 984.35 1245.0 0.0 976.94 0.0 True False 0.0 777.5454629581217 543.1995554456695 0.0 711.0441517308279 942.251645131924 1309.4600081682145 0.0 866.9067295657294 0.0 0.0 SSS(ph)TS(ph)PLGHPPQVRTIR ddPTM_PC-9_AZD4547_30min_R2 1 SSSTSPLGHPPQVRTIR 17 1 Q12846-2 Q12846-2 STX4 Syntaxin-4 2 S(0.001)S(0.009)S(0.935)T(0.131)S(0.81)PLGHPPQVRT(0.115)IR 97.2 0.044031 4487000.0 6807.5 6560.2 4081.7 10934.0 8087.5 5630.8 6727.7 7010.9 5521.3 9712.4 True False 8972.143395203713 8680.656358296967 4027.5739910645993 8413.33522861603 6964.6902254117 5278.705185866371 7326.452266718146 5927.526499454743 5813.144646042646 9372.371832224484 0.9572969954473329 0.9261963261477493 0.429728361524969 0.8976740764476443 0.7431086122154702 0.5632197783400893 0.7817073839866264 0.6324467920782306 0.6202426397612232 1.0 13.194198476364736 -5.0396708598914834 24.90459014063928 0.699282101824902 0.9495221814985697 0.2651840415189348 0.1550651920127325 502.40098818517583 315397.65702196554 0.03677809953114799 0.09734140372938876 9.127022898274566e-06 5.0396708598914834 0.2502400796736677 SSS(ph)TS(ph)PLGHPPQVRTIR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSTSPLGHPPQVRTIR 17 1 Q12846-2 Q12846-2 STX4 Syntaxin-4 2 SSS(0.968)T(0.099)S(0.932)PLGHPPQVRT(0.001)IR 138.28 0.002029 2954000.0 7359.3 7222.2 5548.5 8158.6 8566.7 5143.7 5162.2 4877.3 4980.2 4745.2 True False 7254.355032469667 7205.477439630643 5092.323747829378 8758.61066029176 8062.823548780219 4923.715941550342 5429.47345716141 5103.917163459034 4419.27743216906 5565.401497418443 1.3034737989405902 1.2946913970129492 0.9149966539146356 1.5737607905475488 1.4487406798090356 0.8847009409535409 0.9755762382426345 0.917079776872617 0.7940626447559944 1.0 12.442270054428855 -6.7726979843112245 24.998166436489566 0.9129320888832341 1.2994688220686557 0.5864817606967393 0.16487123781551746 169.07048624025668 375395.2735134657 0.06053336894446615 0.053857885008996784 1.6877262906420968e-07 6.7726979843112245 0.3865367331854216 SSS(ph)TSDILEPFTVER ddPTM_PC-9_AZD4547_30min_R2 2 SSSTSDILEPFTVER 15 0 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 S(0.002)S(0.071)S(0.927)TSDILEPFTVER;SS(0.002)S(0.997)TSDILEPFTVER 230.57 8.004e-25 40954000.0 62072.0 66398.0 96820.0 141082.0 109424.0 95819.0 88699.0 115922.0 95022.0 104912.0 True False 81809.60482219375 87859.85501634124 95536.1035389358 108557.72459517172 94232.36639572783 89827.42278264737 96593.03916726843 98008.9185225567 100044.66892874216 101239.06281272766 0.8080833874719427 0.8678454005334353 0.9436683912775723 1.072290888310396 0.930790583966973 0.8872802679812477 0.9541083894261897 0.9680938937952628 0.9882022427825622 1.0 16.627406531785795 -5.140381907007037 2.7051308922839863 0.966671504642107 0.815645179604475 0.5806360772804882 0.0457255612689616 0.22510155280353697 3.033453018241442 0.013089597432557309 0.051656268076815476 7.237991903954212e-06 5.140381907007037 -0.15102632503763203 SSS(ph)TSDILEPFTVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSTSDILEPFTVER 15 0 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 S(0.031)S(0.031)S(0.938)T(0.001)SDILEPFTVER 137.93 4.6509e-05 14497000.0 55382.0 57620.0 65360.0 52817.0 72068.0 71751.0 67945.0 56121.0 80357.0 61806.0 True False 64757.07875563986 63340.1328026862 66918.43027918045 49857.83472502434 57946.79274446674 67988.25124958341 61508.75772079883 54647.88321511471 81532.06910449179 73010.93854397323 0.8869503672608973 0.8675430567782324 0.9165534865556705 0.6828817122381713 0.7936727550703431 0.9312063727085943 0.8424594854886459 0.7484889840472497 1.1167103276639354 1.0 16.155825005198643 -8.265804549857176 24.99974572550317 1.0583551828027173 0.8347861833597024 0.5783373509658006 0.07671955221913497 284.900064478229 1631616.9318932982 0.06726217132368757 0.019737899554948042 5.422448676952922e-09 8.265804549857176 -0.2235689994430149 SSS(ph)TSDILEPFTVER ddPTM_PC-9_Lapatinib_30min_R1 2 SSSTSDILEPFTVER 15 0 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 SS(0.004)S(0.996)TSDILEPFTVER;S(0.09)S(0.09)S(0.754)T(0.066)S(0.001)DILEPFTVER 187.08 3.3632e-07 32047000.0 38799.0 26629.0 38415.0 28376.0 33997.0 38186.0 35170.0 33552.0 37732.0 28060.0 True False 38245.71914513479 26567.342186580896 35256.66698618828 30462.865699561065 31997.36330067368 36552.8737959137 36990.93051186837 35110.94840759795 33482.22482442535 32910.13361240025 1.162125915244663 0.8072693505130759 1.0713012411746599 0.925637861527336 0.9722647643283149 1.1106874929897246 1.1239981869271571 1.0668734688566701 1.0173834363227727 1.0 15.006244263245256 -6.748791085985462 24.958426311743356 1.0717312124012905 0.9788891935369145 0.1368121924046014 0.09317763738218825 364.09735731744036 718459.0777771351 0.02895803164701039 0.028766015825510898 1.7832363732777992e-07 6.748791085985462 -0.09284201886437604 SSS(ph)TSESGDSDNMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSTSESGDSDNMR 14 0 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 S(0.084)S(0.261)S(0.368)T(0.259)S(0.024)ES(0.004)GDSDNMR 84.734 0.0063143999999999995 1188100.0 6246.1 5128.8 4662.6 4809.3 7058.4 7238.3 4921.8 6048.6 7547.4 8310.3 True False 7303.44136390167 5637.953368941634 4773.7740670089715 4539.850512960971 5675.357189148357 6858.7108057011 4455.571473253772 5889.830659021449 7657.766446722011 9816.89160570139 0.7439667928756619 0.5743114618549175 0.4862816315743458 0.46245295306350803 0.5781216109030134 0.6986642087112119 0.45386784862390595 0.5999690019599271 0.780060201772482 1.0 13.261050570409864 -8.502448786950039 2.2484020897161665 0.9976428323317319 0.5664734879315471 0.6962678219790086 0.08936995491554926 0.16647769485517358 1.926007500033551 0.08807647062625204 0.024280376568697377 3.144497205070667e-09 8.502448786950039 -0.43116934440018484 SSS(ph)TSSSTVTSSAGSEQQNQSSSGSESTDKGSSR ddPTM_PC-9_AZD4547_30min_R2 1 SSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSR 34 1 Q8N488 Q8N488 RYBP RING1 and YY1-binding protein 1 S(0.122)S(0.122)S(0.632)T(0.056)S(0.02)S(0.022)S(0.02)T(0.005)VTSSAGSEQQNQSSSGSESTDKGSSR 101.08 9.6052e-12 0.0 2704.7 996.27 2635.1 6217.8 3903.0 4731.4 2066.9 3133.5 3247.8 3777.3 True False 3564.738338745132 1318.2947943783 2600.156852256247 4784.382274052382 3361.135820684001 4435.544810046201 2250.8500958841432 2649.2895756666676 3419.4720774848884 3645.0578767206375 0.9779648113440198 0.36166635454478296 0.7133376040096076 1.3125668880618062 0.9221076686189483 1.2168653996892755 0.6175073680611002 0.7268168751411331 0.9381118745256515 1.0 11.831726006702624 -5.542518754007067 24.983164674835535 0.9504281205070947 0.6367370162589792 0.22274897391628679 0.23632243088462224 314.56671541918627 400144.35796186124 0.06490735301706334 0.11244067382997362 2.8673535528478668e-06 5.542518754007067 -0.3136911042481155 SSS(ph)VEEKPLSHR ddPTM_PC-9_AZD4547_30min_R2 1 SSSVEEKPLSHR 12 1 Q06190 Q06190 PPP2R3A Serine/threonine-protein phosphatase 2A regulatory subunit B subunit alpha 1 S(0.025)S(0.025)S(0.949)VEEKPLSHR 75.483 0.009293000000000001 109110000.0 108940.0 96170.0 143060.0 172160.0 164070.0 133790.0 185760.0 232000.0 207870.0 167250.0 True False 143580.65390723344 127255.07179314939 141162.93092625667 132471.1718454851 141291.712554349 125424.09015007855 202292.28013519692 196149.73082963645 218857.58382498423 161394.628406938 0.8896247373562604 0.7884715436271544 0.8746445425081346 0.8207904634314984 0.8754424725840206 0.7771267940456862 1.2534015669043224 1.215342373942381 1.3560400738564855 1.0 17.300233037565313 -7.2642975192153685 24.999998511014223 1.2241412209913543 0.8380750256366456 0.8014288268312649 0.0896856611425881 97.92526166690821 856539.9523999745 0.033724646460274 0.023871738453854822 5.441297617942309e-08 7.2642975192153685 -0.38606619535470865 SSS(ph)VEEKPLSHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSVEEKPLSHR 12 1 Q06190 Q06190 PPP2R3A Serine/threonine-protein phosphatase 2A regulatory subunit B subunit alpha 1 S(0.028)S(0.093)S(0.879)VEEKPLSHR;S(0.099)S(0.059)S(0.842)VEEKPLSHR 79.089 0.0066432 73349000.0 148163.0 111668.0 119604.0 195356.0 179418.0 195703.0 221926.0 253547.0 185745.0 156768.0 True False 173244.06954735983 122753.66105189774 122455.81296069613 184410.8366726978 144262.33086288994 185439.9901645581 200903.56267489895 246891.65990525237 188461.16922998382 185188.7974251946 0.9354997276082008 0.66285683993106 0.6612484916111682 0.9957990938797955 0.7790013913836416 1.0013564143342146 1.0848580770986007 1.3331889581764906 1.0176704630641118 1.0 17.498637303121647 -6.955983881776587 1.8886451004897198 1.1410879252684631 0.7935593644634917 0.538039977786199 0.13109703115647245 0.24651411775408244 1.7825041122087404 0.05812068749326074 0.046202020207448964 1.1066648555112132e-07 6.955983881776587 -0.3475285608049714 SSS(ph)VEEKPLSHR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSVEEKPLSHR 12 1 Q06190 Q06190 PPP2R3A Serine/threonine-protein phosphatase 2A regulatory subunit B subunit alpha 1 S(0.097)S(0.097)S(0.806)VEEKPLSHR;S(0.024)S(0.024)S(0.952)VEEKPLSHR 76.868 0.0085808 191409000.0 159163.0 130052.0 134899.0 111138.0 155642.0 133812.0 171842.0 141992.0 183321.0 141724.0 True False 156893.3064330802 129750.87258437114 123808.12494519888 119311.45926549949 146487.44356394542 128089.17269100714 180739.1379306365 148589.4666872807 162673.458524289 166220.80456464025 0.94388489361491 0.7805934577456181 0.7448413287943878 0.7177889649734034 0.8812822435050789 0.7705965148375611 1.087343659561883 0.8939282123947184 0.9786588324509538 1.0 17.342741438758104 -7.245872049062217 24.83687539698065 0.9811433638463157 0.8018849106896313 0.5830234011497284 0.07581099160633877 546.1444254633275 871346.5009365127 0.029005434561390493 0.022385320749474243 5.677118388545958e-08 7.245872049062217 -0.17925845315668443 SSS(ph)VGS(ph)SSSYPISPAVSR ddPTM_PC-9_AZD4547_30min_R2 1 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 SSS(0.999)VGS(0.992)S(0.007)S(0.001)SYPISPAVSR 161.26 5.1481000000000004e-05 14791000.0 10533.0 13472.0 20255.0 28233.0 18981.0 17561.0 15567.0 21730.0 19291.0 21557.0 True False 13882.274899989825 17826.560540681185 19986.40546561811 21724.318045501786 16345.815785909053 16462.907893904834 16952.43284272507 18372.127805724187 20310.682876642946 20802.295991440136 0.6673433983297898 0.8569515859218892 0.9607788233492229 1.0443230907992584 0.7857697915958477 0.7913985985335031 0.8149308542528558 0.8831778863873521 0.9763673627661349 1.0 14.344455149870571 -8.243637229377546 3.096273050378876 0.9972640506407167 0.8537303242856896 0.2518733662489909 0.09627936718852428 0.4111278942071144 7.496979182681603 0.09265398725122033 0.02716174082886541 5.706407352982156e-09 8.243637229377546 -0.14353372635502704 SSS(ph)VGS(ph)SSSYPISPAVSR ddPTM_PC-9_Lapatinib_30min_R1 3 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 S(0.009)S(0.012)S(0.978)VGS(0.531)S(0.392)S(0.065)S(0.011)Y(0.001)PISPAVSR;S(0.209)S(0.315)S(0.476)VGS(0.983)S(0.015)S(0.001)SYPISPAVSR;S(0.016)S(0.02)S(0.964)VGS(0.899)S(0.039)S(0.051)S(0.011)YPISPAVSR 170.48 8.381299999999998e-07 30465700.0 116169.0 100162.0 114888.0 105988.0 132746.0 141254.0 136741.0 129340.0 158086.0 120996.0 True False 114512.40875721426 99930.081042935 105442.35212050467 113782.71108560327 124938.14126867747 135212.89569915654 143820.7799011483 135349.6085788838 140280.68996061955 141909.99738296447 0.8069368675145988 0.704179288885894 0.7430227190826688 0.8017948924242758 0.8804040840865777 0.9528074004135533 1.0134647491608875 0.9537707777812403 0.9885187269932223 1.0 17.11461670348831 -6.42874475782115 1.482154227473 0.9864343367085063 0.7460223551998838 0.929502135581117 0.028554918850853712 0.09287898077679889 0.41309068845215213 0.011156446491826552 0.013340496823891723 3.726106314566791e-07 6.42874475782115 -0.24041198150862253 SSS(ph)VGSS(ph)SSYPISPAVSR ddPTM_PC-9_AZD4547_30min_R2 2 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 S(0.018)S(0.025)S(0.956)VGS(0.075)S(0.758)S(0.139)S(0.026)Y(0.002)PISPAVSR;S(0.006)S(0.011)S(0.982)VGS(0.343)S(0.47)S(0.076)S(0.103)Y(0.007)PISPAVSR 149.52 7.5426e-12 10152000.0 28677.0 23532.0 39767.0 60643.0 47926.0 34906.0 30232.0 52051.0 34559.0 36601.0 True False 37795.68948134511 31138.258806659 39239.66359670381 46662.693275010206 41272.30216297757 32723.32230195558 32922.58943285565 44007.71396298889 36385.71818640316 35319.61013047734 1.070104945714878 0.8816138879117964 1.1109880163383754 1.3211553893893326 1.1685378748663944 0.9264916056850407 0.9321334327087236 1.245985269951057 1.0301845929778788 1.0 15.108181797679338 -12.284696271487118 1.4548785960030841 0.0003055762598323616 1.0778971188527597 0.027945785597159545 0.1348235073000067 3163353.2739267675 106658.39376716447 10407144.82579655 0.03689983159388102 5.191629942147992e-13 12.284696271487118 1.0775915425929274 SSS(ph)VGSS(ph)SSYPISPAVSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 S(0.001)S(0.002)S(0.996)VGS(0.358)S(0.596)S(0.039)S(0.007)YPISPAVSR 211.45 9.149e-20 18897000.0 44609.0 37841.0 46177.0 36774.0 53672.0 54667.0 49725.0 50974.0 68917.0 44813.0 True False 43972.8674797113 37753.38148944413 42380.505308374704 39478.48263446784 50515.11848321199 52329.01984500114 52299.517193706415 53342.4381297359 61154.84173181709 52558.86734043088 0.8366403178914245 0.7183066036204773 0.8063435810720663 0.7511288700108466 0.9611150513579135 0.9956268559986085 0.9950655301408111 1.0149084413145688 1.1635494603738115 1.0 15.68164656502798 -6.434342169510979 2.2228037219849552 1.0351614822330832 0.7727763746501379 0.8224312644074011 0.056006831560093125 0.12461895176732797 1.2165040027041945 0.019567002298514678 0.022330730426558823 3.6783904846999426e-07 6.434342169510979 -0.2623851075829453 SSS(ph)VGSSSSYPIS(ph)PAVSR ddPTM_PC-9_AZD4547_30min_R2 1 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 S(0.219)S(0.318)S(0.463)VGSSS(0.001)S(0.007)YPIS(0.987)PAVS(0.005)R 181.32 6.7171e-08 41074000.0 57681.0 54561.0 75376.0 130650.0 113730.0 82233.0 77317.0 119370.0 88926.0 91847.0 True False 76022.35816066775 72196.77625149244 74376.46499019647 100530.66102237834 97940.55262269832 77090.95751036267 84198.06321712439 100924.1093497144 93626.44681397291 88631.464486051 0.857735552509485 0.8145727555122922 0.8391654749414864 1.1342547661299227 1.1050314150920117 0.8697922115739767 0.9499793747667981 1.138693915698505 1.0563567617537002 1.0 16.435531331146684 -5.741142799974566 24.772460210573897 1.034409245644634 0.8348992437913006 0.5704632595976207 0.07916921398440248 171.83687730702863 209729.15035733816 0.02338810709583089 0.040445150156223506 1.8149188028471124e-06 5.741142799974566 -0.19951000185333345 SSS(ph)VGSSSSYPIS(ph)PAVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 S(0.028)S(0.037)S(0.935)VGSSSSYPIS(0.99)PAVS(0.009)R;S(0.017)S(0.022)S(0.944)VGS(0.053)S(0.057)S(0.08)S(0.079)Y(0.001)PIS(0.746)PAVS(0.001)R;S(0.044)S(0.162)S(0.792)VGS(0.035)S(0.076)S(0.058)S(0.034)Y(0.001)PIS(0.796)PAVS(0.002)R;S(0.002)S(0.008)S(0.507)VGS(0.338)S(0.137)S(0.005)S(0.003)YPIS(0.999)PAVS(0.001)R 153.06 0.00031399 47188200.0 103591.0 107632.0 106153.0 124902.0 163323.0 155918.0 171365.0 201845.0 160052.0 137746.0 True False 121126.9102844874 118316.99364489292 108684.09010749425 117904.1458777476 131321.0305739653 147741.38560204805 155132.0666248392 196546.78262245576 162392.45771136467 162718.25940326427 0.7443965460833678 0.7271279454364626 0.6679280524882136 0.7245907515858194 0.807045448098807 0.9079582472419455 0.9533783559002791 1.2078962947566587 0.9979977557952352 1.0 17.31201662632285 -6.95719507152425 1.3172149272604543 1.0725654615331532 0.7124473248291141 0.8409830821815224 0.06403098403774106 0.1532817026744092 0.5464540669861597 0.033358236251861934 0.025235088230500885 1.1035828136098362e-07 6.95719507152425 -0.36011813670403914 SSS(ph)VGSSSSYPIS(ph)PAVSR ddPTM_PC-9_Lapatinib_30min_R1 3 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 S(0.006)S(0.008)S(0.923)VGS(0.06)S(0.001)S(0.001)S(0.001)YPIS(0.999)PAVSR;S(0.003)S(0.003)S(0.994)VGSS(0.002)S(0.001)S(0.001)YPIS(0.799)PAVS(0.198)R;S(0.008)S(0.01)S(0.982)VGSSSSYPIS(0.983)PAVS(0.017)R 137.52 0.00074285 40377000.0 59277.5 67333.4 75365.0 61545.9 76406.0 92604.0 99817.0 84474.0 106868.0 82629.0 True False 58432.19197983783 67177.49364925161 69168.7806173129 66072.19079710366 71911.94929997565 88643.54279046741 104985.03585166806 88398.97042749872 94831.40047007016 96911.31255377816 0.602945006522459 0.6931852626799724 0.713732780978791 0.6817799600066172 0.7420387507399631 0.9146872584279283 1.0833104318281688 0.9121635864589517 0.9785379845871574 1.0 16.56437746224492 -6.762898732387589 2.6601401602496386 0.9884188620149897 0.6793995504171412 0.9049721112089257 0.04800434867087275 0.07927289140224664 1.1503806022638394 0.01807427294472348 0.016742745360146517 1.7262403651229947e-07 6.762898732387589 -0.30901931159784857 SSS(ph)VGSSSSYPISPAVSR ddPTM_PC-9_AZD4547_30min_R2 9 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 SS(0.005)S(0.995)VGSSSSYPISPAVSR;SSS(0.999)VGSSSSYPISPAVSR;SSS(0.934)VGS(0.065)SSSYPISPAVSR;S(0.015)SS(0.984)VGSSSSYPISPAVSR;S(0.031)S(0.031)S(0.934)VGS(0.003)SSSYPISPAVSR;S(0.225)S(0.015)S(0.759)VGSSSSYPISPAVSR;S(0.028)S(0.071)S(0.818)VGS(0.033)S(0.033)S(0.009)S(0.009)YPISPAVSR;S(0.002)S(0.072)S(0.924)VGS(0.002)SSSYPISPAVSR;S(0.091)S(0.049)S(0.86)VGSSSSYPISPAVSR 351.46 7.847499999999997e-224 6202244000.0 1121945.1 1231415.8 1619732.3 2048593.0 1705675.0 1402406.5 1032776.2 1667638.0 1143203.0 1371143.0 True False 1478700.3038922015 1629446.875701556 1598253.5913877164 1576321.5342963398 1468871.4683436255 1314713.799858405 1124691.2810473924 1409942.8656089369 1203630.3766848184 1323139.7009134463 1.1175692958735666 1.2315002524500223 1.2079250515152269 1.1913492832299615 1.1101408772857253 0.9936318885683618 0.8500170316641149 1.0656039302845837 0.909677470832352 1.0 20.33553396289448 -6.650605898999481 2.51738170519136 0.9571852882224725 1.1905412378985163 0.7636790546659005 0.05924023217731376 0.13023476332266162 1.6800704821982853 0.021022491727342767 0.02080456812651244 2.2356000002916242e-07 6.650605898999481 0.23335594967604378 SSS(ph)VGSSSSYPISPAVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 9 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 S(0.078)S(0.078)S(0.735)VGS(0.066)S(0.017)S(0.017)S(0.005)Y(0.003)PIS(0.001)PAVSR;S(0.033)S(0.041)S(0.891)VGS(0.013)S(0.003)S(0.008)S(0.008)Y(0.001)PISPAVSR;S(0.002)S(0.07)S(0.929)VGSSSSYPISPAVSR;SS(0.005)S(0.993)VGS(0.002)SSSYPISPAVSR;S(0.012)S(0.038)S(0.95)VGSSSSYPISPAVSR;S(0.118)S(0.002)S(0.88)VGS(0.001)SSSYPISPAVSR;S(0.004)SS(0.996)VGSSSSYPISPAVSR;S(0.003)S(0.021)S(0.975)VGSSSSYPISPAVSR;SS(0.001)S(0.998)VGSSSSYPISPAVSR 314.68 2.488899999999999e-156 3234037500.0 343500.7 320714.9 318779.4 346351.7 444973.7 443751.0 378125.0 435071.0 396874.8 353490.4 True False 401648.58406192326 352553.35574106674 326380.30987360736 326946.73713636165 357784.29775543255 420479.9163810101 342306.2626120687 423650.8472458286 402678.3431366446 417575.41129153426 0.9618588001138517 0.8442866754310115 0.7816080665864251 0.7829645335800213 0.856813615171517 1.0069556420491628 0.819747172261262 1.01454931442324 0.9643248434844044 1.0 18.671677236507016 -6.63910529827159 6.4707157737608165 0.9527699047430962 0.8363339671252813 0.4046663224754562 0.06967280309668368 0.231380930839453 12.228929728766657 0.02352667058219044 0.023476056167968204 2.2955919954594527e-07 6.63910529827159 -0.1164359376178149 SSS(ph)VGSSSSYPISPAVSR ddPTM_PC-9_Lapatinib_30min_R1 4 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 SSS(1)VGSSSSYPISPAVSR;S(0.001)S(0.052)S(0.595)VGS(0.323)S(0.027)S(0.001)SYPISPAVSR;S(0.003)S(0.095)S(0.902)VGSSSSYPISPAVSR;S(0.002)S(0.002)S(0.996)VGSSSSYPISPAVSR 268.08 2.6073999999999995e-78 2092634500.0 158161.0 138529.0 147697.0 150342.0 172469.0 184876.0 173917.0 177327.0 236054.0 178708.0 True False 155905.59513682485 138208.2446116965 135553.92278690747 161398.65220620972 162324.71250710034 176969.28444700516 182921.57127758322 185566.25978404083 209467.1127611814 209597.43968655757 0.743833490380292 0.6593985347262827 0.6467346308696401 0.7700411438592633 0.7744594244559895 0.8443294188691133 0.8727280807968515 0.8853460236038466 0.999378203638503 1.0 17.6772615683443 -7.112568368605429 0.5615067631079927 1.0043829802502304 0.6685347067629022 0.9018296793340336 0.036860544632390524 0.25258041832147055 0.16773956643343144 0.03413485051064606 0.03025498057708551 7.716700262300622e-08 7.112568368605429 -0.33584827348732826 SSS(ph)VLSLEGSEK ddPTM_PC-9_AZD4547_30min_R2 1 SSSVLSLEGSEK 12 0 A1L390-3;A1L390;G3V311;A1L390-2;A0A0U1RR71 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 SS(0.006)S(0.99)VLS(0.004)LEGSEK 159.66 7.168e-05 8048200.0 116790.0 100960.0 142850.0 175890.0 144880.0 143660.0 128500.0 176730.0 149040.0 150120.0 True False 153926.7906170903 133593.34561959436 140955.71566346826 135341.27797341085 124765.91281083754 134676.91748979938 139936.25106251473 149420.4393513867 156917.95012880937 144864.3444929718 1.062558155050763 0.9221961835203398 0.9730186966076171 0.9342621778126847 0.8612603277053495 0.9296760908363708 0.9659813224040359 1.0314507677811358 1.0832061586860826 1.0 17.144343022036104 -7.7272940283806895 3.284881656068683 1.046259282545263 0.9430841928847516 0.3879703278816261 0.051116437785283006 0.23752366991308177 5.239984387591418 0.029555332607580354 0.014440406751411377 1.873725518841217e-08 7.7272940283806895 -0.10317508966051137 SSS(ph)VLSLEGSEK ddPTM_PC-9_Lapatinib_30min_R1 3 SSSVLSLEGSEK 12 0 A1L390-3;A1L390;G3V311;A1L390-2;A0A0U1RR71 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 SS(0.001)S(0.677)VLS(0.321)LEGSEK;SS(0.001)S(0.994)VLS(0.005)LEGSEK;S(0.002)S(0.055)S(0.943)VLSLEGSEK 182.37 0.00039703 39707400.0 206819.0 180612.0 184132.0 161589.0 198292.0 198417.0 158802.0 163493.0 183869.0 163901.0 True False 203869.72313404095 180193.8040107686 168993.37773007446 173472.79410510222 186628.85441707168 189931.16744261797 167023.99053584645 171089.48164054065 163159.7369935933 192231.0694656458 1.0605451226003564 0.9373812699042992 0.8791158380371794 0.902418087707222 0.9708568699942893 0.9880357424560922 0.8688709426635938 0.8900199229818913 0.8487688147765942 1.0 17.552482005873557 -7.270071985932555 24.89540027163178 0.8927499139643297 0.9502195847839422 0.15575149063087967 0.05962198440861262 1152.2284369220101 3322874.8563067336 0.02505421585109414 0.01720876156649666 5.3694278872095885e-08 7.270071985932555 0.05746967081961252 SSS(ph)VPHPFQVTLLR ddPTM_PC-9_AZD4547_30min_R2 1 SSSVPHPFQVTLLR 14 0 Q5VV41;Q5VV41-2 Q5VV41 ARHGEF16 Rho guanine nucleotide exchange factor 16 1 S(0.185)S(0.185)S(0.63)VPHPFQVTLLR 110.32 0.00028697 68536000.0 49345.0 44988.0 94589.0 123110.0 111420.0 106130.0 81849.0 107070.0 78537.0 94064.0 True False 65035.683560239035 59529.49121171065 93334.68805664542 94728.89153053953 95951.25624919582 99493.67432265381 89133.40243747678 90524.79172383282 82688.30548353684 90770.84799085351 0.716482053431872 0.6558216930804603 1.0282451923997697 1.0436047875203815 1.0570712775412687 1.0960972220142666 0.981960667002453 0.9972892589144317 0.9109566266459127 1.0 16.469941414820028 -5.263607254027593 24.99791000627472 1.0186320901425994 0.6861518518595613 0.8787141231852295 0.04876041635740851 55.88743430576223 644450.2889144699 0.01349093538048678 0.030466452558301264 5.449952862008604e-06 5.263607254027593 -0.3324802382830381 SSS(ph)VPHPFQVTLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSVPHPFQVTLLR 14 0 Q5VV41;Q5VV41-2 Q5VV41 ARHGEF16 Rho guanine nucleotide exchange factor 16 1 S(0.009)S(0.026)S(0.965)VPHPFQVTLLR;S(0.257)S(0.257)S(0.487)VPHPFQVTLLR 105.17 0.00056481 81521000.0 40797.0 38423.0 68147.0 67910.0 89361.0 72445.0 85330.0 66722.0 74692.0 66671.0 True False 47703.1263225207 42237.38151123935 69771.8829289366 64105.22286719062 71851.35353330604 68645.85666786616 77246.9246642987 64970.6181978026 75784.22919661862 78757.92453265442 0.6056930347719124 0.5362937350352216 0.8859030166546346 0.8139526688595187 0.9123063356439162 0.8716057092058639 0.9808146306886333 0.8249407101994497 0.9622425888736713 1.0 16.26513747268455 -5.266643902034595 24.28534771675084 0.8985327674702719 0.5709933658188144 0.8284763963575419 0.060972823384766214 92.91432704973478 433560.29699792643 0.01502771465642158 0.032896646400668646 5.411978940449209e-06 5.266643902034595 -0.32753940165145745 SSS(ph)VSSQEEK ddPTM_PC-9_AZD4547_30min_R2 1 SSSVSSQEEK 10 0 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4;A0A2R8Y670 P49815 TSC2 Tuberin 1 S(0.012)S(0.115)S(0.873)VSSQEEK 106.01 0.0023783000000000003 4577300.0 110080.0 84227.0 83286.0 113050.0 86323.0 84450.0 106890.0 119410.0 154250.0 147790.0 True False 145083.15019376084 111451.73060124362 82181.57322189424 86988.06910508889 74338.54149344216 79169.32814989258 116403.00292663192 100957.92826882312 162403.3400923837 142615.917083775 1.0172998439475485 0.7814817089159478 0.5762440469644029 0.6099464273261351 0.5212499629320788 0.5551226663107118 0.816199238534187 0.7079008453840304 1.1387462452524513 1.0 17.12177548157853 -8.252225137708793 22.63815884555614 1.0693731245497775 0.6872192161811878 0.5136714213425181 0.1441559388079683 133.33981477166125 327605.6655141003 0.1079851239863811 0.039310628836858985 5.594674990650535e-09 8.252225137708793 -0.38215390836858976 SSS(ph)VSSQEEK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSVSSQEEK 10 0 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4;A0A2R8Y670 P49815 TSC2 Tuberin 1 SSS(0.999)VSSQEEK 132.86 0.00013238 4357800.0 28534.0 38343.0 29073.0 34541.0 56867.0 32099.0 78332.0 59844.0 52741.0 44807.0 True False 28127.099927505245 38254.21913928688 26682.730165025405 37081.2603653982 53522.19486482366 30726.200596423667 82387.64767858037 62624.57071126285 46800.75319264856 52551.8302484254 0.5352258864161636 0.7279331463518929 0.5077412154608049 0.7056131097643218 1.0184649062042388 0.5846837389140088 1.5677407863648847 1.1916724958050202 0.8905637153151453 1.0 15.681453390061272 -6.65345283841972 1.2110727697311643 1.1436306528062385 0.6098002555318089 0.4554320059351532 0.2335357859476746 0.40697957099345217 1.2603811825796352 0.11205396972940737 0.11192835590221212 2.2209928558581837e-07 6.65345283841972 -0.5338303972744296 SSS(ph)YSEANEPDLQMANGGK ddPTM_PC-9_AZD4547_30min_R2 1 SSSYSEANEPDLQMANGGK 19 0 A0A3B3ITG3;Q5VWQ8-2;Q5VWQ8;H0Y3A3;Q5VWQ8-3;Q5VWQ8-4;Q5VWQ8-5 A0A3B3ITG3 DAB2IP Disabled homolog 2-interacting protein 1 S(0.053)S(0.053)S(0.839)YS(0.055)EANEPDLQMANGGK 205.06 4.171299999999999e-72 0.0 17738.0 14049.0 19926.0 26117.0 17794.0 19336.0 15971.0 23386.0 17982.0 16276.0 True False 23378.315026679906 18590.064506831204 19661.768220582882 20096.12915362766 15323.61024679761 18126.91686330754 17392.388060073372 19772.23105681848 18932.491809019422 15706.18219402884 1.4884785327122876 1.1836144695875714 1.2518489839025218 1.279504395490063 0.9756419515255162 1.1541262312746514 1.1073593725842295 1.258882063926106 1.2054165407693511 1.0 13.939044917335476 -1.522880531746045 0.8796218129974795 1.1467689367121263 141.04981819600832 0.5125471803746668 0.09777296066603565 696.1526512577873 1.6967541310185112 0.03333055788978983 195267.60843411848 0.0299998765955746 1.522880531746045 139.90304925929618 SSS(ph)YSEANEPDLQMANGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSYSEANEPDLQMANGGK 19 0 A0A3B3ITG3;Q5VWQ8-2;Q5VWQ8;H0Y3A3;Q5VWQ8-3;Q5VWQ8-4;Q5VWQ8-5 A0A3B3ITG3 DAB2IP Disabled homolog 2-interacting protein 1 S(0.102)S(0.102)S(0.783)YS(0.013)EANEPDLQMANGGK 175.16 1.2672999999999999e-36 0.0 10248.0 12376.0 14037.0 14696.0 15103.0 14096.0 19437.0 18984.0 15503.0 13708.0 True False 11982.78399277378 13604.607489865393 14371.695315618941 13872.630765074851 12143.675567792658 13356.780945410213 17595.786648306228 18485.69011521065 15729.702046205488 16193.151887531703 0.7399908353851856 0.8401457347127448 0.8875168599316828 0.8566973780908217 0.74992661417219 0.8248413303462299 1.0866190084868232 1.1415745522305722 0.9713798867234081 1.0 13.983096203357972 -7.256976248746743 24.36286310907481 1.0616912485708827 0.8196201158698347 0.780459315996899 0.060494586617567236 119.30750280985194 651265.6001986669 0.024055024237487097 0.01796620854610474 5.5338037236325975e-08 7.256976248746743 -0.24207113270104796 SSSALDS(ph)PAGPR ddPTM_PC-9_AZD4547_30min_R2 2 SSSALDSPAGPR 12 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 S(0.001)S(0.001)S(0.068)ALDS(0.93)PAGPR;SSS(0.006)ALDS(0.994)PAGPR 115.92 0.00070057 20714800.0 88868.0 78484.0 110606.0 148158.0 124411.0 125425.0 84024.0 110338.0 86940.0 108659.0 True False 117126.17543076967 103852.41816172974 109139.29217132356 114002.46211828191 107138.68014017883 117582.15492244271 91501.9732239437 93287.79741500209 91535.47090847233 104854.88148322578 1.1170312127958202 0.9904395169083625 1.0408603836797352 1.0872403888656297 1.0217805659083063 1.121379884838771 0.8726534418770172 0.8896848300756113 0.8729729089733964 1.0 16.678034501610078 -7.269572101362312 24.9730713057722 0.8996348564023128 1.0580234876928372 0.6842615590803234 0.05112368885434177 332.5131015918063 1021040.1724257132 0.020052237010208394 0.013790207349994062 5.37561180063401e-08 7.269572101362312 0.15838863129052438 SSSALDS(ph)PAGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSALDSPAGPR 12 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 S(0.003)SSALDS(0.997)PAGPR 124.6 0.00031766 6407900.0 98265.0 97752.0 80816.0 127290.0 122550.0 112670.0 130220.0 108490.0 111850.0 94908.0 True False 114899.32367778246 107456.1725395381 82742.95993638661 120158.35397974792 98537.20723253592 106761.38685580072 117884.61888884283 105642.25245465676 113485.59465058918 112114.06910868511 1.024843042369618 0.9584539513534954 0.7380247688287391 1.0717508956281352 0.8789013548068836 0.9522568193676441 1.051470344676935 0.9422747144450312 1.0122333044622123 1.0 16.774607806636546 -7.013368177840744 24.128841298301925 0.9974240782487017 0.9307654903330935 0.11694938560214463 0.08690304669784657 923.627423217093 1667096.597043893 0.031759464305518216 0.025766505162580198 9.696875555852507e-08 7.013368177840744 -0.06665858791560819 SSSALDS(ph)PAGPR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSALDSPAGPR 12 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 SSS(0.003)ALDS(0.997)PAGPR;SSSALDS(1)PAGPR 166.24 0.00054913 23338000.0 185084.0 152524.0 190644.0 177935.0 174663.0 169347.0 152183.0 172693.0 186500.0 130155.0 True False 182444.6682197516 152170.8400490465 174969.98622712147 191020.93347375953 164389.66574067032 162104.42357713814 160062.29110286216 180716.94722679193 165494.40606793514 152652.11832936393 1.1951663050368349 0.9968472217379977 1.1462008398049495 1.2513480688267333 1.076890825622094 1.0619205639019027 1.0485428754909902 1.18384827675221 1.0841278056218162 1.0 17.2198880841719 SSSAS(ph)SPEMK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSASSPEMK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SSS(0.001)AS(0.773)S(0.226)PEMK 97.45200000000001 0.0045261 7000700.0 30145.0 33744.0 30030.0 30192.0 33308.0 24657.0 18774.0 26822.0 26735.0 19991.0 True False 29715.12677208406 33665.8678412252 27561.049319152244 32412.420397559505 31348.88892604755 23602.477588274356 19746.025858112494 28068.24803852506 23723.82276796914 23446.417713666884 1.2673631910414678 1.4358640305892618 1.1754908428116482 1.3824039473060463 1.3370438635397308 1.0066560221059486 0.8421766642245977 1.1971230906700139 1.0118314472466536 1.0 14.517079895402333 -6.762435963095174 24.995687888189213 1.0132912958130196 1.3215698331163668 0.6940560878510714 0.10226338891706982 15.368224712621089 385448.0630342697 0.0347391359712154 0.0323978661776361 1.7280807679624123e-07 6.762435963095174 0.3082785373033472 SSSASS(ph)PEMK ddPTM_PC-9_AZD4547_30min_R2 4 SSSASSPEMK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SSSASS(1)PEMK;SSSAS(0.009)S(0.991)PEMK;SSSAS(0.135)S(0.864)PEMK;SSSAS(0.035)S(0.965)PEMK 123.62 0.00038751 229449200.0 396164.0 347925.0 422912.0 464219.0 463290.0 433467.0 430589.0 430678.0 417921.0 477685.0 True False 522135.91127689934 460384.9522057978 417303.9105542078 357200.4816620542 398970.1804675099 406362.23996624554 468910.58683857735 364126.61109588994 440011.45085736876 460961.39354599913 1.1327107184840537 0.9987494802205299 0.9052903700764373 0.7749032493030446 0.8655175597209679 0.8815537388939597 1.0172448135654661 0.7899286495443872 0.9545516327788961 1.0 18.8142864015078 -4.932547937005661 2.2436699342972193 0.8891248436224515 1.1547260030784843 0.48215667466459833 0.07536427562654893 0.36170566782441305 2.7579537478523437 0.01987654766043201 0.17060932801757928 1.1680247972961707e-05 4.932547937005661 0.2656011594560328 SSSASS(ph)PEMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSSASSPEMK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SSSAS(0.05)S(0.95)PEMK;SSSAS(0.021)S(0.979)PEMK;SSSAS(0.117)S(0.883)PEMK 119.45 0.00069456 191298000.0 555480.0 596860.0 559270.0 628720.0 578590.0 467240.0 504630.0 480320.0 430210.0 366340.0 True False 649511.7927699029 656112.3162896794 572605.1178432864 593494.8567377431 465219.44294306706 442737.11187098915 456827.79319518217 467712.1089411068 436501.00737264095 432754.5420541554 1.5008780489902338 1.5161303984825023 1.3231637387912845 1.3714353035339661 1.075019203114104 1.0230675102090194 1.0556279571942984 1.080779202734692 1.0086572524477784 1.0 18.723189436176888 -6.050826902508611 1.2409271444765646 1.0293226850888162 1.4982014094673781 0.9338597860514463 0.05101034153819307 0.1076875575842205 0.3374916127361373 0.019410537246284523 0.03491573380858915 8.895555989004398e-07 6.050826902508611 0.46887872437856193 SSSASS(ph)PEMK ddPTM_PC-9_Lapatinib_30min_R1 4 SSSASSPEMK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SSSAS(0.042)S(0.958)PEMK;SSS(0.001)AS(0.117)S(0.883)PEMK;SSSAS(0.008)S(0.992)PEMK;SSSAS(0.259)S(0.741)PEMK 103.31 0.0025351999999999996 53749500.0 473564.0 587755.0 536656.0 593226.0 580704.0 406353.0 375639.0 448972.0 471954.0 363213.0 True False 466810.8905189981 586394.0894090597 492534.2152320672 636853.8189839247 546548.132427991 388974.2294451084 395087.7494042568 469832.87817286816 418797.5706240547 425993.88309909846 1.0958159472219569 1.3765317124815324 1.1562002056200642 1.4949834827458641 1.2829952591146672 0.9130981567512831 0.9274493486385297 1.1029099168158043 0.9831070051459643 1.0 18.700473189193197 -6.7515358603896525 24.79355983622216 0.9881282873831426 1.2915164822158687 0.6306289129354784 0.11311969891885751 117.34827459158767 293782.14085758507 0.03691898006985139 0.03648841651491117 1.7720017220791463e-07 6.7515358603896525 0.30338819483272605 SSSFS(ph)LPSR ddPTM_PC-9_AZD4547_30min_R2 2 SSSFSLPSR 9 0 Q14153-2;Q14153 Q14153-2 FAM53B Protein FAM53B 1 S(0.009)S(0.012)S(0.131)FS(0.848)LPSR;S(0.004)S(0.001)S(0.246)FS(0.749)LPSR 132.88 0.0011875 15578800.0 74143.0 66756.0 102264.0 135967.0 129389.0 118883.0 85892.0 123900.0 94952.0 99618.0 True False 97718.93172979647 88333.5715152697 100907.91254188934 104621.90881920945 111425.57076671353 111449.22721662116 93536.22160514804 104754.10193875848 99970.96887165008 96130.40414135947 1.0165247155946737 0.9188931670918126 1.0496982036349765 1.088333184008706 1.1591085230731222 1.1593546101474348 0.9730139225005577 1.0897083277078279 1.039951613275682 1.0 16.552705178567088 -5.438948931487674 5.259028618812871 1.078957772474901 0.9687602536029173 0.31349192858628405 0.060741747470677884 0.2437996134546556 11.247154490565821 0.016473096027650968 0.03487628733398045 3.6395783126507546e-06 5.438948931487674 -0.11019751887198381 SSSFS(ph)LPSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSFSLPSR 9 0 Q14153-2;Q14153 Q14153-2 FAM53B Protein FAM53B 1 S(0.005)S(0.001)S(0.213)FS(0.781)LPSR 133.99 0.0011404000000000002 8149300.0 45295.0 34241.0 45585.0 39848.0 42542.0 39590.0 41697.0 34238.0 46355.0 38046.0 True False 44649.08499391433 34161.71706826076 41837.17726318864 42778.55484903122 40039.76320079005 37896.82798879755 43855.866635012084 35828.82247196411 41134.01176020978 44622.20040689164 1.000602493529623 0.7655767030033033 0.9375866022224921 0.9586832217808855 0.8973058889002286 0.849281918937924 0.9828261769950456 0.8029371511322995 0.921828403465663 1.0 15.445474036964727 -8.544513049841854 22.93344020218748 1.000000003826194 0.8968883309262045 0.14864860505391375 0.07207843738819052 3169.282330491801 3359594.9857888473 0.06542205359599779 0.016891901543871005 2.8542167479333615e-09 8.544513049841854 -0.10311167289998957 SSSGESLAQS(ph)PDSSK ddPTM_PC-9_AZD4547_30min_R2 2 SSSGESLAQSPDSSK 15 0 Q9H7U1-3;Q9H7U1-2;Q9H7U1 Q9H7U1-3 CCSER2 Serine-rich coiled-coil domain-containing protein 2 1 SSS(0.001)GES(0.288)LAQS(0.709)PDS(0.001)SK;SSSGES(0.06)LAQS(0.938)PDS(0.002)S(0.001)K 115.58 0.00015771 20338200.0 83302.0 61984.0 75667.0 106550.0 102688.0 98590.0 82594.0 92169.0 85056.0 90240.0 True False 109790.30321076138 82019.1158368158 74663.60614006045 81986.54368109001 88431.5437239045 92425.1517145991 89944.70599422086 77926.39888291722 89551.88651473455 87080.72506691837 1.2607876556653785 0.941874516706046 0.8574068036604447 0.9415004711787406 1.015512257803872 1.0613732446942044 1.0328888043261195 0.8948754023698541 1.0283778235185477 1.0 16.410065799547922 -7.087160644780062 0.005562799914007702 5.8694431457125734e-06 1.9878406011023249 0.014662889944131785 0.1050370201318875 45603.204293706694 128.8808272415756 22770.884157481643 23275.175493205043 8.181620954070347e-08 7.087160644780062 1.9878347316591791 SSSGESLAQS(ph)PDSSK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSGESLAQSPDSSK 15 0 Q9H7U1-3;Q9H7U1-2;Q9H7U1 Q9H7U1-3 CCSER2 Serine-rich coiled-coil domain-containing protein 2 1 SSSGES(0.002)LAQS(0.605)PDS(0.391)S(0.001)K;SSSGES(0.014)LAQS(0.915)PDS(0.071)S(0.001)K 179.9 1.3879e-09 8369600.0 71520.0 70808.0 66933.0 67188.0 74461.0 72575.0 63341.0 65887.0 77066.0 66301.0 True False 70500.11168483847 70644.0484264306 61430.02710885165 72129.22965259774 70081.35037595849 69471.13643058807 66620.48705010665 68948.35055231885 68386.01553904283 77761.0395094708 0.9066251188199717 0.9084761324188138 0.7899846439343171 0.9275754299016652 0.9012398859125723 0.8933925892557922 0.8567334936667442 0.8866696097075887 0.8794380318271575 1.0 16.246759884567403 -10.91271066384801 5.801509236751297 1.0000338149836114 0.8827787232685717 0.48493608770759367 0.036061912569156744 1.5612260857117522e-05 1.64200465972457e-06 0.034561919489679356 0.00838008098600287 1.2226139200996591e-11 10.91271066384801 -0.11725509171503978 SSSGLLEWESK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSGLLEWESK 11 0 P14866;M0QXS5;A0A3B3ITJ4;P14866-2;M0R076;M0QYT0 P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 0 122.69 0.0029686 5108100.0 29852.0 22947.0 27714.0 22944.0 24881.0 20989.0 23599.0 22794.0 26927.0 20070.0 False True 29426.305005813658 22893.86763135949 25435.46189913371 24631.378298940264 23417.54849792809 20091.34939774873 24820.840749206178 23853.09245358811 23894.197706119503 23539.072758405993 1.2501046794761823 0.9725900364186566 1.080563459750151 1.046403932378526 0.9948373386783255 0.8535318958379083 1.054452781719809 1.013340359597214 1.0150866158305532 1.0 14.522769870987972 -4.7569394416582265 24.982905482763623 1.0042358998446153 1.2501050500765953 0.6159356367220821 0.058434450701062214 95.76766931497166 531619.1710468966 0.015171347611590013 0.11782140403197183 1.7500907055456524e-05 4.7569394416582265 0.24586915023198008 SSSGPVWSGASSACT(ph)SPAVGK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSGPVWSGASSACTSPAVGK 21 0 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 SSSGPVWSGASSACT(0.754)S(0.246)PAVGK 188.09 2.3488e-52 0.0 6171.4 6694.0 8070.5 4633.9 6039.9 5385.2 5188.0 4563.6 6056.8 5640.5 True False 6083.39470430385 6678.500454278138 7406.974643030906 4974.692464237245 5684.644956900281 5154.887549514333 5456.609254921042 4775.641516240879 5374.619403068466 6615.452909506181 0.9195734271741575 1.009530344427569 1.1196473989539455 0.7519806326621691 0.8592979248225983 0.779219143425076 0.8248277675864157 0.7218918464945075 0.8124340807180898 1.0 12.691624214851757 -5.769389523032778 24.99999961950357 0.8097579415684603 1.0155783942876149 0.526192202852708 0.0842352414528544 120.77936187214395 379803.1846109199 0.02257219743988969 0.03415929190548262 1.7006325099724967e-06 5.769389523032778 0.2058204527191546 SSSHLS(ph)PSEEVR ddPTM_PC-9_AZD4547_30min_R2 1 SSSHLSPSEEVR 12 0 A0A2R8YH03;Q5VWN6;Q5VWN6-2 A0A2R8YH03 FAM208B Protein FAM208B 1 SSS(0.001)HLS(0.968)PS(0.032)EEVR 105.65 0.002686 0.0 2418.5 1802.2 5381.3 15093.0 10313.0 9898.0 6905.9 11689.0 6123.6 8847.4 True False 3187.532692074944 2384.7259060581673 5309.940445921044 11613.542034525493 8881.217965337966 9279.076495294688 7520.511721499008 9882.733636498384 6447.280994422825 8537.655218938971 0.37334989646853867 0.27931860035389583 0.6219436496032389 1.3602730183766758 1.0402408785068848 1.0868413232137826 0.8808638354025298 1.1575465842864727 0.7551582757899269 1.0 13.059624187237041 -5.551980943370823 5.468500508733241 1.0415564266699735 0.35088505817338606 0.7841125761633729 0.15299683308812573 0.0711161359192395 5.90670598310343 0.04090801576863192 0.07450990611597266 2.8055567417066783e-06 5.551980943370823 -0.6906713684965875 down SSSISEEKGDS(ph)DDEKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSISEEKGDSDDEKPR 17 2 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 SSSIS(0.001)EEKGDS(0.999)DDEKPR 73.758 0.028767 12074000.0 22812.0 24483.0 15702.0 25003.0 23879.0 19962.0 27713.0 26695.0 19077.0 17276.0 True False 26673.621042462477 26913.510437489855 16076.395230166614 23602.1629708197 19200.08136683578 18915.157578907376 25087.824015254955 25994.28453569049 19355.96503486179 20408.002043259236 1.3070177563644834 1.3187724295813361 0.7877495894056248 1.1565151219011904 0.940811419272548 0.9268500433708577 1.2293130881737375 1.2737300045634015 0.9484497793479527 1.0 14.316847328045819 -5.196554351906843 24.984611646038708 1.0470525226706615 1.3128961290565349 0.38052636389577166 0.1419728991192517 223.4137106546137 86026.31456940198 0.036899548934484584 0.09762702020674136 6.359832066278586e-06 5.196554351906843 0.26584360638587334 SSSISEEKGDS(ph)DDEKPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSISEEKGDSDDEKPR 17 2 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 SSSIS(0.002)EEKGDS(0.998)DDEKPR 108.25 0.0015095 16679000.0 70830.0 58604.0 43686.0 70656.0 53509.0 50632.0 51158.0 51763.0 48076.0 51275.0 True False 69819.95121136871 58468.30603861906 40094.30571283664 75852.2779415066 50361.70582274162 48466.587388956745 53806.710921983526 54168.097950122006 42661.174617276374 60137.81543035718 1.160999126950728 0.9722386092712081 0.6667070532229094 1.2613075050813514 0.83743823187364 0.8059253074312893 0.8947234038505204 0.9007327180491213 0.7093901617806571 1.0 15.87598484099257 SSSKES(ph)LVR ddPTM_PC-9_AZD4547_30min_R2 1 SSSKESLVR 9 1 Q13439-3;Q13439-4;Q13439;Q86W71;Q13439-5;E7EVX2 Q13439-3;Q13439-5 GOLGA4 Golgin subfamily A member 4 1 S(0.004)S(0.004)S(0.143)KES(0.848)LVR 72.096 0.015668 178530000.0 274950.0 247990.0 284050.0 412320.0 387560.0 408650.0 383470.0 365220.0 324200.0 342520.0 True False 362378.3806847238 328147.9177912359 280283.31140502705 317265.9942804978 333753.98377255653 383097.0508993919 417598.08712017606 308783.64092068904 341336.5501325826 330528.4790549742 1.096360536679964 0.992797712104734 0.8479853603126577 0.9598749105904711 1.0097586287475273 1.159044001275528 1.2634254340628852 0.934211907559504 1.032699364086599 1.0 18.334415057278022 -6.555282096180232 7.9426058197291045 1.0855305226518235 0.9687274421362722 0.19031936461441978 0.10079027222077194 0.35577005248560123 73.47521496787341 0.03544778427263409 0.03566323043226608 2.784312029971796e-07 6.555282096180232 -0.11680308051555133 SSSLDALDADS(ph)EGEGHSEPSHICYTPGSQSSSR ddPTM_PC-9_AZD4547_30min_R2 1 SSSLDALDADSEGEGHSEPSHICYTPGSQSSSR 33 0 Q8N1W1-5;Q8N1W1-4;Q8N1W1-3;Q8N1W1;Q8N1W1-6;Q8N1W1-2 Q8N1W1-5 ARHGEF28 Rho guanine nucleotide exchange factor 28 1 SSSLDALDADS(0.499)EGEGHS(0.44)EPS(0.056)HICY(0.002)T(0.001)PGSQSSSR 53.758 0.0016706 6226700.0 12196.0 9603.9 17554.0 22603.0 20823.0 19325.0 16043.0 27250.0 17907.0 15448.0 True False 16074.074307440982 12708.172860499411 17321.22249042015 17392.22756286887 17932.085881143455 18116.604695046455 17470.795920590885 23039.1386427052 18853.527462134945 14907.170222005256 1.0782780412417374 0.852487270973817 1.161939002001291 1.1667021509686184 1.202916825533592 1.2152946820385524 1.1719726588216808 1.5455071820871755 1.2647287970391767 1.0 13.863718801212416 -5.703564355622455 1.0009152167038684 1.2697463337782282 0.9504176353985335 0.30596880174634333 0.14215275920875636 0.7242662337162186 1.330898642484242 0.054811734222520676 0.18108231328393287 1.978953749638975e-06 5.703564355622455 -0.3193286983796947 SSSLDALDADS(ph)EGEGHSEPSHICYTPGSQSSSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSLDALDADSEGEGHSEPSHICYTPGSQSSSR 33 0 Q8N1W1-5;Q8N1W1-4;Q8N1W1-3;Q8N1W1;Q8N1W1-6;Q8N1W1-2 Q8N1W1-5 ARHGEF28 Rho guanine nucleotide exchange factor 28 1 SSSLDALDADS(0.887)EGEGHS(0.046)EPS(0.054)HICY(0.004)T(0.005)PGS(0.001)QS(0.001)S(0.001)S(0.001)R 54.31100000000001 0.0011433 6411600.0 16771.0 15723.0 24577.0 15882.0 19751.0 20146.0 16367.0 19241.0 20012.0 13034.0 True False 16531.84246457527 15686.594359518243 22556.373929963516 17050.01526079889 18589.28501196005 19284.402542619737 17214.403175653955 20135.007102723906 17758.037824297677 15286.909533286695 1.081437842526495 1.026145561034508 1.4755352532732549 1.1153343469242816 1.2160263636991213 1.2614977867585757 1.1260878556368907 1.31714046314467 1.1616499584582607 1.0 13.900009154354391 -10.094780125044146 15.142611899595675 1.0000032907896481 1.2023627624952786 0.18720720934490964 0.12337157399224732 0.0 0.0 0.11642817232665398 0.028237979547082917 8.039330350274882e-11 10.094780125044146 0.2023594717056305 SSSLEMTPY(ph)NTPQLSPATTPANKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSLEMTPYNTPQLSPATTPANKK 24 1 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7;B4DGD8;A0A0A0MQV8;B0QZ65 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 SSSLEMT(0.008)PY(0.495)NT(0.495)PQLS(0.002)PATTPANKK 107.92 5.6006e-07 24388000.0 95930.0 81247.0 123520.0 172660.0 205690.0 190330.0 162490.0 196270.0 185140.0 140420.0 True False 112169.05429613453 89312.66521728314 126465.18525220866 162986.419971273 165386.52105801948 180348.7597431843 147097.77087427475 191118.12046525461 187847.32224953116 165877.0344358916 0.6762181074528782 0.5384269469309859 0.7624032204475244 0.9825737512462234 0.9970429096496677 1.0872436944421364 0.8867880437730233 1.152167454133732 1.1324492440340237 1.0 17.339754634395945 -5.670002641187678 2.2167961215367478 1.0432315360632272 0.604376913177726 0.8356120043098914 0.07843105064852601 0.11313231249562616 1.1251604976257366 0.023440022049203625 0.04862930802962243 2.137949087398378e-06 5.670002641187678 -0.43885462288550114 SSSLEMTPYNT(ph)PQLSPATTPANKK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSLEMTPYNTPQLSPATTPANKK 24 1 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7;B4DGD8;A0A0A0MQV8;B0QZ65 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 S(0.007)S(0.007)S(0.025)LEMT(0.024)PY(0.405)NT(0.533)PQLSPATTPANKK 136.02 1.4093e-06 15118000.0 15096.0 10767.0 14109.0 10483.0 12555.0 11762.0 9324.4 10233.0 11560.0 11421.0 True False 14880.728271732658 10742.069673022512 12949.012482314984 11253.954790262856 11816.539584079714 11258.966678561172 9807.171807360395 10708.462537403137 10257.991067803376 13395.104632474087 1.110907953317284 0.8019399599895803 0.9666973747201921 0.8401543025636106 0.8821535858281078 0.8405284607681061 0.7321459649956464 0.7994310482235684 0.7658014886225428 1.0 13.709418230021411 -2.925727673426377 1.794592341625264 0.8395574596422573 199.99999999917807 0.46702155750964447 0.08178856598035646 919.8527809078516 5.118084232679039 0.02179977767912332 752361.9005001059 0.0011865125236883627 2.925727673426377 199.1604425395358 SSSLEMTPYNTPQLS(ph)PATTPANKK ddPTM_PC-9_AZD4547_30min_R2 3 SSSLEMTPYNTPQLSPATTPANKK 24 1 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7;B4DGD8;A0A0A0MQV8;B0QZ65 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 SSSLEMTPYNTPQLS(1)PATTPANKK;SSSLEMTPYNT(0.013)PQLS(0.983)PAT(0.003)TPANKK;SSSLEMTPYNTPQLS(1)PATTPANKK 121.25 3.6669000000000002e-09 53300400.0 113689.0 98432.0 185273.0 302974.0 275981.0 219337.0 237060.0 262617.0 213045.0 268321.0 True False 149839.73712189717 130248.21905732849 182816.15896477245 233128.02520163808 237665.80192882125 205621.82271655352 258157.8807539283 222035.57698830465 224306.12376001218 258927.16346055578 0.5786945452894645 0.5030303399479759 0.7060524532128594 0.9003614069913994 0.9178867089587014 0.7941299783631135 0.9970289609774964 0.8575213740451334 0.866290429950129 1.0 17.98218679747388 -5.5592128384721535 2.7849248409476606 0.8995576918477496 0.5420953342239652 0.8507003733455368 0.061708913729818654 0.08960927698187614 1.3990158157894508 0.016766250115976978 0.035568719778812326 2.7592252872917805e-06 5.5592128384721535 -0.3574623576237844 SSSLEMTPYNTPQLS(ph)PATTPANKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSLEMTPYNTPQLSPATTPANKK 24 1 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7;B4DGD8;A0A0A0MQV8;B0QZ65 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 SSSLEMTPY(0.001)NT(0.002)PQLS(0.996)PAT(0.002)TPANKK 102.45 9.257799999999999e-07 23653000.0 41669.0 36603.0 59187.0 69200.0 85190.0 81089.0 75351.0 81406.0 65380.0 65707.0 True False 48722.73869973565 40236.703939200306 60598.2425479475 65322.94834942699 68497.63104153189 76836.55009097385 68213.20778600204 79269.17875678664 66336.05881319205 77619.15896367433 0.6277153649981937 0.5183862396400228 0.780712434365688 0.8415827898882291 0.8824835511756665 0.9899173234656312 0.8788192077412966 1.021257893220468 0.8546351145628522 1.0 16.24412518054823 -5.592813851345351 1.3651150454053185 0.9402580044415568 0.5538573250303032 0.8303984383660328 0.06332921767909556 0.17040842787904223 0.6018855220234818 0.019241972343661574 0.059873443458299015 2.5537956839728763e-06 5.592813851345351 -0.38640067941125367 SSSLEMTPYNTPQLS(ph)PATTPANKK ddPTM_PC-9_Lapatinib_30min_R1 3 SSSLEMTPYNTPQLSPATTPANKK 24 1 Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;Q14C86-3;Q14C86-4;H0Y7I9;C9IZ08;F8W9S7;H0Y4E7;B4DGD8;A0A0A0MQV8;B0QZ65 Q14C86-5 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 SSSLEMTPYNTPQLS(0.999)PAT(0.001)TPANKK;SSSLEMTPYNTPQLS(0.999)PAT(0.001)TPANKK;SSSLEMTPYNTPQLS(1)PATTPANKK 124.08 3.2273000000000002e-09 39571000.0 353197.0 223730.0 265558.0 230348.0 211419.0 222062.0 158566.0 159397.0 241710.0 134384.0 True False 348160.3460116021 223211.96693093033 243724.8463235245 247288.56033840214 198983.75008574684 212564.92591180492 166775.77161060311 166803.16652735698 214486.07448086102 157612.09534457567 2.208969719300063 1.4162108970313383 1.54635877272418 1.568969435992672 1.262490354250563 1.3486587145935085 1.0581406918421683 1.0583145041164992 1.3608478081072772 1.0 17.26601872765786 -1.5228787452803376 0.3602306710874493 1.1134650190648914 12.758392894125002 0.7546107980898764 0.165665920790093 32.27917681308668 0.4504544144551964 0.1348675635370362 257.7894589473269 0.029999999999999995 1.5228787452803376 11.64492787506011 up SSSLGNS(ph)PER ddPTM_PC-9_AZD4547_30min_R2 2 SSSLGNSPER 10 0 Q5SQI0-7;Q5SQI0-6;Q5SQI0-5;Q5SQI0-4;Q5SQI0-3;Q5SQI0-2;Q5SQI0 Q5SQI0-7 ATAT1 Alpha-tubulin N-acetyltransferase 1 1 SSSLGNS(1)PER;SS(0.001)S(0.14)LGNS(0.859)PER 101.72 0.0034935 16430700.0 34510.0 42636.0 45730.0 41629.0 43398.0 42980.0 39131.0 51904.0 45700.0 38463.0 True False 45483.46214740801 56417.25320757746 45123.5903205488 32032.077211638607 37372.93680400827 40292.45380559363 42613.58319320838 43883.42943526497 48115.60870160087 37116.42207722607 1.2254269027540723 1.5200078577130423 1.215731145277491 0.8630162989576757 1.0069110844318045 1.0855694474472612 1.1481059005241583 1.1823184180834878 1.2963428587348589 1.0 15.179770024814802 -5.51963548444156 24.99254483660164 1.086478618837125 1.3715054456864693 0.4503625960158183 0.12812645093208314 112.28354785529173 865254.3486593986 0.03612591686734105 0.06422734980063023 3.0224875147473474e-06 5.51963548444156 0.28502682684934433 SSSLGNS(ph)PER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSLGNSPER 10 0 Q5SQI0-7;Q5SQI0-6;Q5SQI0-5;Q5SQI0-4;Q5SQI0-3;Q5SQI0-2;Q5SQI0 Q5SQI0-7 ATAT1 Alpha-tubulin N-acetyltransferase 1 1 SSSLGNS(0.999)PER;SSSLGNS(1)PER 131.12 0.00019049 12488500.0 34896.0 43214.0 41552.0 37672.0 45873.0 33853.0 41544.0 28519.0 28305.0 33563.0 True False 40803.20357258331 47504.000328623384 42542.75726683755 35561.35997427189 36884.51495208586 32077.689085199465 37608.65156748642 27770.406468378256 28718.90707720096 39647.706215438186 1.0291441162035042 1.1981525506291733 1.0730193831559436 0.8969336026916195 0.9303064028890432 0.8090679675362638 0.9485706780394325 0.7004290820124394 0.724352297233737 1.0 15.274949781989756 -5.901651225587428 1.3567452238207647 0.8290564583922992 1.1288106805467093 0.5603295180095844 0.09793275078996302 0.30616555992575095 1.1428408791644347 0.034400135824047745 0.07018567055198521 1.254147955228713e-06 5.901651225587428 0.29975422215441005 SSSLGNS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 3 SSSLGNSPER 10 0 Q5SQI0-7;Q5SQI0-6;Q5SQI0-5;Q5SQI0-4;Q5SQI0-3;Q5SQI0-2;Q5SQI0 Q5SQI0-7 ATAT1 Alpha-tubulin N-acetyltransferase 1 1 S(0.001)S(0.002)S(0.016)LGNS(0.981)PER;SSS(0.004)LGNS(0.996)PER;SSSLGNS(1)PER 127.52 0.00031017 17233800.0 38383.0 59058.0 63217.0 48583.0 60319.0 61917.0 57909.0 65274.0 66958.0 54364.0 True False 37835.65138141988 58921.25482951273 58019.54228467686 52155.95588813702 56771.15501171675 59268.954245576584 60907.24466908685 68306.86833445248 59416.48494100163 63760.74496452336 0.593400397101253 0.92409922221418 0.9099570953407004 0.8179947696212886 0.8903778499342246 0.9295524115747704 0.9552467541427849 1.071299721677634 0.9318662285715312 1.0 15.960380865062666 -3.720628821366467 0.5032507424168817 0.9750641009031477 2.2744490522890836e-140 0.6293828685053295 0.07349118140049035 9.030774650220962 0.7748594184654756 0.04412937663727473 6.553170680795398 0.0001902703769765273 3.720628821366467 -0.9750641009031477 SSSLGS(ph)TPHEELER ddPTM_PC-9_AZD4547_30min_R2 1 SSSLGSTPHEELER 14 0 Q9NRA8;Q9NRA8-3;B1AKL4;Q9NRA8-2 Q9NRA8 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 S(0.023)S(0.073)S(0.242)LGS(0.652)T(0.011)PHEELER 72.207 0.013216 3963900.0 9538.4 10994.0 15759.0 24506.0 18165.0 12860.0 9864.0 19108.0 9389.9 12670.0 True False 12571.412788954993 14547.595500612313 15550.025363252316 18856.52031392577 15643.103300723764 12055.862167052903 10741.876890899986 16155.297658158195 9886.230944139219 12226.427156447853 1.0282163896363792 1.1898484581360587 1.2718372394711972 1.5422756028920028 1.2794500879575483 0.9860494822230221 0.8785785702927156 1.321342486356562 0.8085952517146856 1.0 13.577715256289936 -6.758717329899954 24.755872082774218 1.0114761279321012 1.2743802998041762 0.36811374462762436 0.1718022616287314 73.8512616153834 671645.877812016 0.05948752253340159 0.056929968419348206 1.7429409356674337e-07 6.758717329899954 0.26290417187207504 SSSLIQLTSQNSS(ph)PNQQR ddPTM_PC-9_AZD4547_30min_R2 2 SSSLIQLTSQNSSPNQQR 18 0 H7C419;O95639 H7C419 CPSF4 Cleavage and polyadenylation specificity factor subunit 4 1 SS(0.001)S(0.042)LIQLT(0.313)S(0.089)QNS(0.089)S(0.466)PNQQR;SSSLIQLT(0.078)S(0.04)QNS(0.44)S(0.442)PNQQR 160.45 6.9233e-18 4373200.0 46404.0 36414.0 52046.0 65864.0 69791.0 58916.0 45040.0 57363.0 42480.0 53090.0 True False 61159.50673683927 48184.113385419034 51355.836033747735 50680.07238865612 60101.7243303503 55231.97320638329 49048.47274595855 48498.86642060541 44725.406075361185 51231.335259338346 1.1937909958279145 0.9405203503189219 1.0024301684463064 0.9892397325212845 1.1731438196195574 1.0780896677159262 0.9573920433201688 0.9466641104530871 0.873008791376538 1.0 15.644738873272859 -7.357983643369048 4.6095780658444285 0.9362742493650588 1.056041501025778 0.3504301557542556 0.07884319894233777 0.2824772225484122 10.068340128284271 0.035039633778769834 0.023148886932044047 4.385472142635892e-08 7.357983643369048 0.11976725166071922 SSSLIQLTSQNSS(ph)PNQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSLIQLTSQNSSPNQQR 18 0 H7C419;O95639 H7C419 CPSF4 Cleavage and polyadenylation specificity factor subunit 4 1 SSSLIQLT(0.002)S(0.002)QNS(0.276)S(0.719)PNQQR;SSSLIQLT(0.025)S(0.072)QNS(0.221)S(0.683)PNQQR 243.86 2.4988000000000002e-53 10186500.0 49055.0 45847.0 55832.0 52157.0 62182.0 58985.0 56156.0 41031.0 44782.0 43052.0 True False 57359.04261958601 50398.38716773264 57163.24662403909 49234.81238527548 49997.88347722193 55891.72276284199 50836.497145767586 39953.97972593805 45436.85203077949 50856.98680055551 1.1278498044827043 0.9909825638191788 1.1239998714083215 0.9681032141829072 0.983107467087999 1.0989979210139027 0.9995971122931785 0.7856143715832892 0.8934239892931128 1.0 15.634158366613379 -7.582895826611957 7.380132850665715 0.8806507102724159 1.0435162233351591 0.4784529222686088 0.07227084016962568 0.1807200923503287 18.583844953712763 0.032741576329721266 0.01881227145050164 2.6127880037086688e-08 7.582895826611957 0.16286551306274322 SSSLIQLTSQNSS(ph)PNQQR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSLIQLTSQNSSPNQQR 18 0 H7C419;O95639 H7C419 CPSF4 Cleavage and polyadenylation specificity factor subunit 4 1 SSSLIQLTS(0.001)QNS(0.115)S(0.883)PNQQR;SSSLIQLTSQNS(0.031)S(0.969)PNQQR 219.23 9.034099999999999e-28 10661500.0 65160.0 59019.0 71829.0 65372.0 67383.0 65693.0 48372.0 54017.0 64704.0 42934.0 True False 64230.806451119446 58882.345131616516 65923.49688795836 70179.67495459919 63419.66442007515 62883.46352786247 50876.46547398624 56526.82701875353 57416.35415667382 50355.08469404104 1.275557510058571 1.1693425895197547 1.309172594754064 1.3936958974652298 1.2594490666715163 1.2488006704773553 1.0103540840634688 1.1225644314216165 1.1402295221135514 1.0 15.61984984382916 -7.150223832185374 5.2084890555910555 1.0792386238542 1.2801734666848206 0.7047923122024726 0.06588287408105055 0.14244159960139022 5.627252471558839 0.02709811371797369 0.02084526571768237 7.075810083374002e-08 7.150223832185374 0.20093484283062057 SSSMS(ph)SLTGAYTSGIPSSSR ddPTM_PC-9_AZD4547_30min_R2 1 SSSMSSLTGAYTSGIPSSSR 20 0 A8CG34-2;A8CG34 A8CG34-2 POM121C Nuclear envelope pore membrane protein POM 121C 1 SS(0.005)S(0.315)MS(0.575)S(0.105)LTGAYTSGIPSSSR 118.52 1.2848e-05 15436000.0 36580.0 37066.0 56620.0 60505.0 54991.0 47801.0 40752.0 59080.0 44763.0 55380.0 True False 48211.679088733305 49046.85963486412 55869.181805149194 46556.50704293152 47356.448863754486 44811.995913475585 44378.84905291526 49950.54352334026 47129.080794524285 53441.16305636013 0.9021450195215306 0.9177730578793414 1.0454334937701193 0.8711731627889926 0.8861418082127334 0.8385295781496362 0.8304244614981982 0.9346829422604708 0.8818872587937693 1.0 15.705663785516059 -4.380576792662661 15.818403128605448 0.907189455814242 0.002779114941980407 0.0 0.06448297196752985 13079690.900752205 10319981.414662156 0.016684667965103747 425420983.16015065 4.1631610082070456e-05 4.380576792662661 -0.9044103408722617 SSSMS(ph)SLTGAYTSGIPSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSMSSLTGAYTSGIPSSSR 20 0 A8CG34-2;A8CG34 A8CG34-2 POM121C Nuclear envelope pore membrane protein POM 121C 1 S(0.001)S(0.001)S(0.025)MS(0.766)S(0.206)LT(0.002)GAYTSGIPSSSR 134.06 5.2712e-05 8906800.0 56091.0 63843.0 66078.0 64039.0 117880.0 103830.0 112870.0 110150.0 99932.0 95757.0 True False 65586.09845225158 70180.91111631182 67653.55012221064 60451.10244723928 94782.26020866063 98384.97201773134 102178.13649196505 107258.6792135723 101393.31644722981 113116.98608800507 0.5798076904314403 0.6204276965239424 0.598084801071133 0.5344122446845277 0.8379135927023373 0.8697630251674827 0.9032961363775235 0.9482101930308238 0.8963580091176205 1.0 16.78745606074861 -6.399574492112586 3.365907234514045 0.9157795267285344 0.586681207120486 0.9404207747414244 0.0405348863273656 0.058389185398019676 1.2281271246944816 0.013569331204221992 0.015466354832853996 3.9849741440998323e-07 6.399574492112586 -0.32909831960804836 SSSMS(ph)YVDGFIGTWPK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSMSYVDGFIGTWPK 16 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 S(0.027)S(0.033)S(0.16)MS(0.78)YVDGFIGTWPK 97.235 0.0019512999999999998 7742200.0 124480.0 111730.0 129810.0 119270.0 130490.0 125950.0 126730.0 119520.0 128030.0 121870.0 True False 122704.89237316394 111471.29604967087 119137.52288109044 128041.51367305673 122814.83475321069 120563.41210379009 133291.45930534755 125073.33552921162 113609.91318433093 142935.06711843252 0.8584659793211812 0.7798736747876465 0.8335080066977265 0.8958019627679235 0.8592351564186086 0.8434837897679384 0.9325315473137568 0.8750360429437438 0.7948358333242082 1.0 17.12500037933406 -14.522878745280336 0.21435689799809818 1.6920015838057465 0.8353761998032385 0.49651816916970914 0.04344207553261903 132.2620138236064 1.317553815229398 39.635614736710416 0.09173098392312602 3.0000000000000132e-15 14.522878745280336 -0.856625384002508 SSSMSSLTGAYTS(ph)GIPSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSMSSLTGAYTSGIPSSSR 20 0 A8CG34-2;A8CG34 A8CG34-2 POM121C Nuclear envelope pore membrane protein POM 121C 1 SSS(0.002)MSSLT(0.001)GAY(0.009)T(0.011)S(0.265)GIPS(0.265)S(0.265)S(0.181)R 50.376000000000005 0.043973000000000005 8976300.0 7757.8 9623.4 9968.3 13515.0 14650.0 8237.4 10035.0 9925.7 10282.0 10537.0 True False 9071.04231646569 10578.747553165047 10205.982076988272 12757.798366221188 11779.43766590494 7805.416242886072 9084.412152891542 9665.160892148457 10432.354798367087 12447.274689153903 0.7287573017384972 0.849884638794304 0.8199370811573227 1.0249471217452817 0.9463467273016083 0.6270783314268323 0.7298314193071809 0.7764881175612138 0.8381236100989606 1.0 13.60354228065076 -6.723726271254535 24.99999568263551 0.7763045580522113 0.8780214800919639 0.09759382286004314 0.11445103445356854 326.79181740032493 216629.1359258644 0.03842298864411307 0.03842215738186483 1.8891816944120382e-07 6.723726271254535 0.10171692203975258 SSSNDS(ph)VDEETAESDTSPVLEK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSNDSVDEETAESDTSPVLEK 22 0 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 S(0.082)S(0.082)S(0.082)NDS(0.751)VDEET(0.003)AES(0.001)DTSPVLEK;S(0.051)S(0.051)S(0.046)NDS(0.836)VDEET(0.007)AES(0.008)DT(0.001)SPVLEK 99.774 0.00042412 0.0 24295.0 29175.0 31891.0 26403.0 31496.0 30980.0 27623.0 28971.0 28821.0 28322.0 True False 23948.548844842648 29107.447080006645 29269.04508281999 28344.76469782602 29643.46720351847 29655.057617907245 29053.183779622963 30317.098423835254 25574.87548141531 33217.41996330718 0.7209635447694864 0.8762705565982994 0.8811354137422875 0.8533102429127964 0.8924072741430072 0.8927561999295849 0.8746369769752095 0.9126867305565666 0.7699235976083025 1.0 15.01965240135388 -13.397802809503569 0.0169279492814265 1.9879849551812085 1.9314579279017657e-06 0.33904348873088286 0.05883137095277623 4883.076339463191 7.533415809270169 545.7842955900696 356.8642247822298 4.0012638506631164e-14 13.397802809503569 -1.9879830237232807 SSSPAGET(ph)EGDREPQARPGEGTAPLPPPGQK ddPTM_PC-9_AZD4547_30min_R2 1 SSSPAGETEGDREPQARPGEGTAPLPPPGQK 31 2 Q9BTC0 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 S(0.07)S(0.07)S(0.074)PAGET(0.746)EGDREPQARPGEGT(0.041)APLPPPGQK 41.188 0.026973 10395000.0 21325.0 21685.0 32151.0 35028.0 32295.0 31277.0 15916.0 31014.0 18443.0 29356.0 True False 28105.906412444972 28694.252176712584 31724.656732909785 26952.83577720527 27811.396702277692 29321.244245638725 17332.493166622484 26221.498930820497 19417.85932786926 28328.255375270986 0.9921509828303754 1.0129198496904646 1.1198944768269659 0.9514470771374652 0.9817546592211082 1.0350529482742012 0.6118447090021929 0.9256305615527043 0.685459060949443 1.0 14.789954134144105 -7.225133997779255 24.93456969880239 0.7995360763875379 1.0157125862023508 0.4649309927006422 0.11018225948095514 461.2822850489347 316809.4935009449 0.03903586809073006 0.03023604522481858 5.9547838551335836e-08 7.225133997779255 0.21617650981481296 SSSPAGET(ph)EGDREPQARPGEGTAPLPPPGQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSPAGETEGDREPQARPGEGTAPLPPPGQK 31 2 Q9BTC0 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 S(0.003)S(0.003)S(0.01)PAGET(0.983)EGDREPQARPGEGTAPLPPPGQK 86.604 5.477e-08 10107000.0 10363.0 10438.0 10926.0 13836.0 12472.0 12932.0 13254.0 12962.0 10900.0 9849.8 True False 12117.251221420242 11474.215657661203 11186.517277085739 13060.81377691722 10028.20113100113 12253.823154515096 11998.485169349735 12621.76123437424 11059.391879225943 11635.490769026104 1.0414043947056013 0.9861393804037714 0.9614134460803715 1.1224978848064882 0.8618631848083614 1.0531419256620447 1.0311971714411847 1.0847639764343766 0.9504877876459025 1.0 13.506244442472179 SSSPALKPKPNPPS(ph)PENTASSAPVDWR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSPALKPKPNPPSPENTASSAPVDWR 27 2 Q5T0Z8 Q5T0Z8 C6orf132 Uncharacterized protein C6orf132 1 S(0.007)S(0.007)S(0.007)PALKPKPNPPS(0.886)PENT(0.013)AS(0.04)S(0.04)APVDWR 44.933 0.012223999999999999 4669500.0 6466.1 9053.8 7433.9 5205.2 9111.7 8277.3 7573.1 8941.6 10456.0 9343.3 True False 6373.892228262487 9032.836482363808 6822.713437683841 5588.007772038179 8575.76772029145 7923.299174328722 7965.198062537109 9357.059378915657 9278.335173438756 10958.276955835316 0.5816509524217099 0.8242935015028795 0.6226082316755761 0.5099348916402909 0.7825835899981363 0.7230424277705029 0.7268659201294978 0.853880534013424 0.8466965391395783 1.0 13.41973335095983 -8.083773094324627 0.6196800301897846 0.9969666468541513 0.6542528309570211 0.6192527420267924 0.08563515236520884 0.5037101876118546 0.4351065788926633 0.08582693299423276 0.0417511416894044 8.245688146493613e-09 8.083773094324627 -0.3427138158971301 SSSPAPADIAQTVQEDLR ddPTM_PC-9_AZD4547_30min_R2 2 SSSPAPADIAQTVQEDLR 18 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 0 ; 188.63 5.5561e-18 1922000.0 9734.3 8113.8 11019.099999999999 12424.0 12579.8 11226.4 10265.2 9104.8 10309.8 8379.2 False True 12829.604913981857 10736.427175993098 10872.979534247954 9559.838748886554 10833.311913154139 10524.411433297259 11178.782913672607 7697.862367489991 10854.754980126141 8085.846758429989 1.5866742590200849 1.3278049283830067 1.3446927525447114 1.1822928426042503 1.3397869433847172 1.3015843297209309 1.3825123388614857 0.9520168508591261 1.3424388693502505 1.0 12.981183146823755 -1.5228787452989394 0.08776256051462232 0.8237723109592096 2.5710795672834887 0.4623047544107698 0.13000433207071088 151.41885895350745 0.9622805996716488 2.5886961399226105 31.880226843616597 0.02999999999871503 1.5228787452989394 1.7473072563242793 SSSPAPADIAQTVQEDLR ddPTM_PC-9_Lapatinib_30min_R1 3 SSSPAPADIAQTVQEDLR 18 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 0 ;; 117.48 0.0011867000000000002 744060.0 17390.0 17051.6 17572.699999999997 17812.0 20348.3 23468.6 17907.8 20668.6 22043.5 14232.3 False True 17142.01541106458 17012.118067847172 16127.940438583628 19121.953899090153 19151.453000297035 22464.902685978628 18834.978260461638 21628.938610433925 19560.72890165428 16692.334091652298 1.0269393912764522 1.0191575350959934 0.9661884521379837 1.1455530301572918 1.1473202546236192 1.3458215347614655 1.1283609683969158 1.2957408168130533 1.1718390486466745 1.0 14.026898080625633 -5.9371339857855014 3.015117902648696 1.2003083851892753 1.0054854543998708 0.4220366622589936 0.09081724226094426 0.21341985549757603 3.9421537176178862 0.02562646880306068 0.03967744141696194 1.1557556207727102e-06 5.9371339857855014 -0.1948229307894045 SSSPAT(ph)EQSWMENDFDELREEGFR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSPATEQSWMENDFDELREEGFR 24 1 Q9UN81 Q9UN81 L1RE1 LINE-1 retrotransposable element ORF1 protein 1 S(0.041)S(0.041)S(0.118)PAT(0.453)EQS(0.347)WMENDFDELREEGFR 46.568999999999996 0.033497000000000006 1583600.0 1066.1 778.43 746.67 1190.8 991.12 583.69 660.53 1302.1 950.32 513.21 True False 1050.8972185012044 776.6275931615967 685.2816748295505 1278.375404392351 932.8242702168918 558.7269393478465 694.7290114018883 1362.6003195497533 843.2849542867561 601.9176646906596 1.7459152308501968 1.2902555261619124 1.1384973643890874 2.123837659838974 1.54975393635655 0.9282447951332182 1.154192761162653 2.2637652946271767 1.4009971857532062 1.0 9.233422346417031 -6.566211778274879 24.999864750328587 1.39653117788862 1.5623695049602324 0.05791359581650379 0.42308641083234966 638.7968264942039 368532.8927888399 0.14735090494245415 0.1473509666750921 2.7151149541075047e-07 6.566211778274879 0.1658383270716124 SSSPGKLLGS(ph)GYGGLTGGSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSPGKLLGSGYGGLTGGSSR 21 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 SSS(0.019)PGKLLGS(0.563)GY(0.416)GGLT(0.001)GGSSR 70.628 0.012906 7160300.0 10178.0 876.74 2041.3 14475.0 11230.0 21647.0 8482.1 24428.0 20576.0 15043.0 True False 11900.934375336798 963.7769530271966 2089.97233367336 13664.012678583176 9029.562115229523 20511.793212634424 7678.614082913945 23786.790883605463 20876.885074032394 17770.176819677523 0.6697138973968164 0.05423564226777831 0.11761122890792299 0.7689294719595896 0.5081301219935404 1.1542818859247936 0.4321067911046982 1.3385793019946508 1.1748270873092668 1.0 14.117170416324186 -6.57673969136967 0.7664936761785165 1.109741288572495 0.25698445740503606 0.50506111743976 0.29808649224317857 0.5356304407090674 0.7000924651030356 0.19056401082713847 0.22777416669136402 2.650088079805586e-07 6.57673969136967 -0.852756831167459 SSSPLPTVQLHPQS(ph)PTAGK ddPTM_PC-9_AZD4547_30min_R2 1 SSSPLPTVQLHPQSPTAGK 19 0 A0A087X2C4;H0YAH0;O60245;O60245-2 A0A087X2C4 PCDH7 Protocadherin-7 1 SSSPLPT(0.005)VQLHPQS(0.775)PT(0.219)AGK 62.658 0.008357 7963400.0 24107.0 32378.0 31024.0 35108.0 35084.0 27967.0 34108.0 34500.0 34257.0 27360.0 True False 31772.524543250227 42843.55531370069 30612.60148927851 27014.39301319293 30213.192193921957 26218.21906889338 37143.54592404874 29168.817731131323 36067.7550829484 26402.13472773588 1.2034074089423028 1.6227307282351233 1.1594744820811578 1.0231897265797172 1.144346565362478 0.9930340610432045 1.4068387388777632 1.1047901251897256 1.3660923805929461 1.0 14.688366962035026 -5.363371336015722 10.441432366787073 1.151938031123113 1.4127855953027793 0.2943796575870625 0.16308483998357745 0.5093127745909269 48.866574146035276 0.04070670962228996 0.08481239338973842 4.331403707991332e-06 5.363371336015722 0.26084756417966615 SSSPLPTVQLHPQS(ph)PTAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSPLPTVQLHPQSPTAGK 19 0 A0A087X2C4;H0YAH0;O60245;O60245-2 A0A087X2C4 PCDH7 Protocadherin-7 1 S(0.001)S(0.001)S(0.001)PLPT(0.004)VQLHPQS(0.728)PT(0.265)AGK 50.722 0.032335 6412800.0 29407.0 43445.0 32777.0 31347.0 54809.0 24414.0 36832.0 28283.0 26475.0 19759.0 True False 34385.02428527504 47757.93248199756 33558.52798746471 29590.729218345194 44069.569899698596 23133.68686160931 33343.0063194122 27540.601218315576 26862.14678922084 23341.150287842065 1.473150374392024 2.046083071873013 1.4377409670741321 1.2677493976703629 1.888063328337916 0.9911116879984779 1.4285074175106056 1.1799161943043108 1.1508493136781177 1.0 14.510588040580698 -6.553974063392463 0.33291424028185984 0.9873305848326932 1.8723838501849939 0.4115617739539895 0.25632275030186674 2.18539639450467 0.4575042741748093 0.3002402876409156 0.7169853303060896 2.792710620414785e-07 6.553974063392463 0.8850532653523007 SSSPLPTVQLHPQS(ph)PTAGKK ddPTM_PC-9_AZD4547_30min_R2 1 SSSPLPTVQLHPQSPTAGKK 20 1 A0A087X2C4;H0YAH0;O60245;O60245-2 A0A087X2C4 PCDH7 Protocadherin-7 1 SSSPLPTVQLHPQS(0.954)PT(0.045)AGKK 77.506 0.00071864 12828000.0 85710.0 104810.0 121380.0 142540.0 144410.0 105480.0 96586.0 125240.0 96391.0 104600.0 True False 112963.99712125004 138687.78282874075 119770.42189171676 109679.60522104705 124361.16419804648 98884.31892540764 105181.96688812513 105887.03572889559 101486.03147387327 100937.98583776233 1.1191425723792143 1.3739899967060338 1.18657431984252 1.0866038618735183 1.2320551392607757 0.9796541718629541 1.0420454303217834 1.0490305988380615 1.0054295281559493 1.0 16.623109678283434 -6.385186150507294 0.868302978933859 1.0120945256161185 1.245465280884782 0.5321345355257621 0.08075279860135073 0.46444302436540363 0.76335389647145 0.04260397941208922 0.06063547269360608 4.119209206662832e-07 6.385186150507294 0.23337075526866347 SSSPVT(ph)ELAS(ph)RSPIRQDR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSPVTELASRSPIRQDR 18 2 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 SSS(0.002)PVT(0.965)ELAS(0.516)RS(0.516)PIRQDR 88.18700000000001 0.019459 7007600.0 42750.0 24554.0 38045.0 29649.0 27774.0 29495.0 23696.0 24107.0 38174.0 18663.0 True False 42140.37716061013 24497.146721593275 34917.08695794696 31829.486366164587 26140.38792578495 28233.567606203185 24922.862934581528 25227.099226930255 33874.442129958996 21888.874683115664 1.9251961451045168 1.1191597136096514 1.5951979013741084 1.454139914772173 1.1942316955173926 1.2898592556693471 1.1386086902770831 1.1525078192525624 1.5475643503998218 1.0 14.417910166374389 -4.7518111932033325 24.987133093135505 1.290573540933233 1.925197415387611 0.5177409603649321 0.18730931001331194 323.6820083667475 839962.6373796426 0.04597941535559534 0.5852306090228513 1.770878669364131e-05 4.7518111932033325 0.634623874454378 SSSQIPEGFGLT(ph)SGGSNYSLAR ddPTM_PC-9_AZD4547_30min_R2 1 SSSQIPEGFGLTSGGSNYSLAR 22 0 A2RRE0;Q9Y4E6-2;Q9Y4E6 A2RRE0 WDR7 WD repeat-containing protein 7 1 S(0.008)S(0.008)S(0.261)QIPEGFGLT(0.582)S(0.141)GGSNYSLAR 118.24 2.9413e-06 2525900.0 6242.3 6808.9 9095.4 12515.0 12185.0 10102.0 7117.5 10885.0 6560.6 10019.0 True False 8227.221552094034 9009.743769703398 8974.789053171211 9629.860104822532 10493.32307841008 9470.320343045758 7750.943711575492 9202.973362416365 6907.379922269647 9668.237859546256 0.8509535730930133 0.9318909919874725 0.9282755744687906 0.9960305326284633 1.0853397724435532 0.9795291014375409 0.8016914585859449 0.9518770117275822 0.7144404205415174 1.0 13.239037251618143 -10.85799454162068 6.3238401786855425 1.0000047835885961 0.9233741104123847 0.05580382094807701 0.09963878769470862 6.9381793669030555e-06 7.294108709192449e-07 0.09960812356357393 0.024157010632112577 1.3867732582595988e-11 10.85799454162068 -0.07663067317621142 SSSQLGS(ph)PDVSHLIR ddPTM_PC-9_AZD4547_30min_R2 2 SSSQLGSPDVSHLIR 15 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 SSSQLGS(0.999)PDVSHLIR;S(0.007)S(0.007)S(0.003)QLGS(0.98)PDVS(0.004)HLIR 88.98299999999999 0.0026506999999999998 12088800.0 25267.0 32279.0 35343.0 41252.0 35617.0 41300.0 35436.0 45012.0 38992.0 36061.0 True False 33301.38041375134 42712.55549975121 34874.328727294036 31741.988737046675 30672.19434417167 38717.50447117302 38589.735351371855 38056.429672860395 41053.03751625433 34798.51536611415 0.9569770452385253 1.2274246487349725 1.0021786378063045 0.9121650278205881 0.8814224981000027 1.1126194340139888 1.1089477509419694 1.093622221306565 1.1797353158413952 1.0 15.086738136208679 SSSQLGS(ph)PDVSHLIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSQLGSPDVSHLIR 15 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 SSSQLGS(1)PDVSHLIR;SSSQLGS(1)PDVSHLIR 126.43 1.3382e-05 12647700.0 38253.0 32468.0 54203.0 55313.0 62626.0 52543.0 54523.0 43544.0 45668.0 36804.0 True False 44728.47736881105 35691.2084664633 55495.40508602218 52213.99193716554 50354.88486450258 49787.55258333486 49358.186727663735 42401.01613868167 46335.80810463218 43476.273859696295 1.0288019969962416 0.8209353124797117 1.2764526524309148 1.2009767006636085 1.1582152837431394 1.145166044910056 1.1352901788904255 0.9752679421312731 1.0657722935080403 1.0 15.407940678826973 -10.636238436731233 13.648087881234476 1.0000073660581499 1.0921452744855695 0.04662492328333856 0.12115051761230959 0.0 0.0 0.12482017711952031 0.030273339674828655 2.3107957667613157e-11 10.636238436731233 0.09213790842741965 SSSQLGS(ph)PDVSHLIR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSQLGSPDVSHLIR 15 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 S(0.001)S(0.001)SQLGS(0.998)PDVSHLIR 77.668 0.0071893 4375600.0 22714.0 22114.0 20922.0 19152.0 21212.0 16596.0 16859.0 17574.0 20099.0 15680.0 True False 22390.094194762558 22062.796391680124 19201.87392125551 20560.501969199115 19964.351864396554 15886.227767165556 17731.876528279463 18390.5521970412 17835.238968147052 18390.267107713316 1.2174969544282268 1.1996996162402915 1.0441324103009784 1.1180099695547951 1.0855933601977446 0.8638388814104007 0.9641989659216147 1.0000155021852708 0.9698194628541599 1.0 14.166654813740564 -5.578478976893809 0.7191926545988782 0.9631778123092581 1.2583176853515878 0.7052324333976971 0.05686441116189089 0.7196836214253516 0.5635823140943529 0.02960480528868119 0.14684309821687744 2.6394960906562857e-06 5.578478976893809 0.2951398730423297 SSSQPS(ph)PSDPK ddPTM_PC-9_AZD4547_30min_R2 3 SSSQPSPSDPK 11 0 A0A0A0MT50;A0A087X1S4;A0A087WUP2;E7ESE9;J3KNW2;E7EUP4;B5MDK9;Q9H322;Q9NNX9;Q9H320;Q9H321-2;Q9H321 A0A0A0MT50 VCX3B;VCX;VCX3A;VCX2 Variable charge X-linked protein 2;Variable charge X-linked protein 3;Variable charge X-linked protein 1;Variable charge X-linked protein 3B 1 S(0.003)S(0.008)S(0.048)QPS(0.912)PS(0.028)DPK;SSS(0.01)QPS(0.822)PS(0.168)DPK;SSS(0.001)QPS(0.943)PS(0.056)DPK 122.78 0.00063525 18221700.0 120927.0 116647.0 124376.0 139761.0 144190.0 141120.0 131300.0 128530.0 132622.0 141929.0 True False 159379.2705621443 154350.86159358954 122726.69297416527 107541.26073592523 124171.70740057001 132295.74409133024 142985.44563819628 108668.64182557413 139632.12816682082 136960.10890982536 1.1636911786269075 1.1269767731800964 0.8960761929224853 0.7852013377612782 0.9066268155666024 0.9659436250772395 1.0439933698675576 0.7934327936108875 1.0195094708836332 1.0 17.063396228511074 -5.228486248958915 6.117546671152309 0.9187445382343389 1.1489202500896276 0.5237923324565351 0.08332755431771877 0.1456540022098289 17.221968496015503 0.02156910563279552 0.05660018795630838 5.908996749008453e-06 5.228486248958915 0.23017571185528873 SSSQPS(ph)PSDPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSSQPSPSDPK 11 0 A0A0A0MT50;A0A087X1S4;A0A087WUP2;E7ESE9;J3KNW2;E7EUP4;B5MDK9;Q9H322;Q9NNX9;Q9H320;Q9H321-2;Q9H321 A0A0A0MT50 VCX3B;VCX;VCX3A;VCX2 Variable charge X-linked protein 2;Variable charge X-linked protein 3;Variable charge X-linked protein 1;Variable charge X-linked protein 3B 1 S(0.204)S(0.016)S(0.314)QPS(0.438)PS(0.029)DPK;S(0.001)S(0.001)S(0.057)QPS(0.901)PS(0.041)DPK;SSS(0.004)QPS(0.975)PS(0.021)DPK 117.48 0.0011582 22002800.0 130870.0 131643.0 118935.0 159898.0 144649.0 129319.0 153721.0 138230.0 133087.0 118021.0 True False 153023.70619967848 144711.64704172185 121770.86146349956 150939.43345631074 116306.06682153499 122537.28398691126 139159.4340363369 134601.6089667917 135033.14559913272 139417.2730462778 1.0975950314914291 1.0379750218876154 0.8734273652238145 1.0826451425872337 0.8342299650555398 0.8789246935437947 0.9981505949420246 0.9654586266517521 0.9685539147958386 1.0 17.089049788831325 -5.04358888409139 5.742015603379501 0.9487018291752021 1.085072704719922 0.3326364263153686 0.0689432276645934 0.1871642699461937 16.085894593604866 0.01735580986810905 0.0513546762718492 9.045052998588432e-06 5.04358888409139 0.13637087554471994 SSSQPS(ph)PSDPK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSQPSPSDPK 11 0 A0A0A0MT50;A0A087X1S4;A0A087WUP2;E7ESE9;J3KNW2;E7EUP4;B5MDK9;Q9H322;Q9NNX9;Q9H320;Q9H321-2;Q9H321 A0A0A0MT50 VCX3B;VCX;VCX3A;VCX2 Variable charge X-linked protein 2;Variable charge X-linked protein 3;Variable charge X-linked protein 1;Variable charge X-linked protein 3B 1 SSS(0.006)QPS(0.969)PS(0.025)DPK;SSSQPS(0.997)PS(0.003)DPK 145.61 0.00020818 18497400.0 96966.0 98678.0 101173.0 108396.0 95164.0 98972.0 92675.0 91073.0 92012.0 84110.0 True False 95583.24705861318 98449.51715375844 92854.94647907377 116367.80343845603 89566.64061962266 94739.19827500063 97473.25803774239 95304.58405833246 81648.63963068547 98648.30143046995 0.9689294764591857 0.997984919417476 0.941272633513315 1.1796229813493067 0.907939004735441 0.9603733353865747 0.9880885592991607 0.9661046635000174 0.827674054664121 1.0 16.590006589758957 SSSQPS(ph)SCCSDPSKPGGNVEGATQSLAEQMR ddPTM_PC-9_AZD4547_30min_R2 1 SSSQPSSCCSDPSKPGGNVEGATQSLAEQMR 31 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 S(0.02)S(0.011)S(0.106)QPS(0.519)S(0.198)CCS(0.054)DPS(0.067)KPGGNVEGAT(0.02)QS(0.006)LAEQMR 52.931000000000004 0.006906300000000001 81093000.0 153880.0 130410.0 197250.0 191360.0 221690.0 190630.0 216920.0 257070.0 192020.0 193050.0 True False 202810.6390971645 172562.48219345562 194634.33611913948 147244.90848252832 190912.17014794634 178709.8759646421 236225.45977027836 217345.7383809256 202169.78518340035 186291.37825984726 1.0886743175751026 0.9263041789983325 1.044784455068313 0.7904010902595007 1.0248041102667338 0.9593029888660217 1.2680429012704006 1.1666977850030311 1.0852342554544054 1.0 17.50720138097835 -7.233604574987567 24.57791579089617 1.143885221155979 0.9676866676114086 0.3767508742568193 0.0985575460841438 550.5361728948501 486119.70161710057 0.03643498825542427 0.028215562674934976 5.839765728031847e-08 7.233604574987567 -0.17619855354457026 SSSQPS(ph)SCCSDPSKPGGNVEGATQSLAEQMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSSQPSSCCSDPSKPGGNVEGATQSLAEQMR 31 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 S(0.011)S(0.03)S(0.248)QPS(0.444)S(0.197)CCS(0.052)DPS(0.012)KPGGNVEGAT(0.004)QS(0.001)LAEQMR;S(0.002)S(0.002)S(0.017)QPS(0.561)S(0.216)CCS(0.021)DPS(0.096)KPGGNVEGAT(0.063)QS(0.023)LAEQMR;S(0.003)S(0.003)S(0.022)QPS(0.351)S(0.343)CCS(0.113)DPS(0.163)KPGGNVEGAT(0.001)QSLAEQMR 70.943 6.5368e-05 123953000.0 225893.0 265399.0 259442.0 278275.0 286435.0 247757.0 278017.0 239208.0 232673.0 185170.0 True False 264132.22330987995 291746.05875911354 265628.08121926384 262684.15392972226 230310.11794085163 234764.18676872866 251681.2170912258 232929.0434618267 236075.40245093024 218739.85519508703 1.2075175924127266 1.3337581233146316 1.2143561171436212 1.2008975396616348 1.0528950827705608 1.0732574846012861 1.1505960670347861 1.0648678689765283 1.0792518914323235 1.0 17.73885658304291 -6.020900257551985 2.1845883483543154 1.0770499656866275 1.2641374796261953 0.7502806377612827 0.04802933243304835 0.15075764711251988 1.4384347319658004 0.01484085296740359 0.022763229137423912 9.530150135363549e-07 6.020900257551985 0.1870875139395678 SSSQPS(ph)SCCSDPSKPGGNVEGATQSLAEQMR ddPTM_PC-9_Lapatinib_30min_R1 3 SSSQPSSCCSDPSKPGGNVEGATQSLAEQMR 31 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 S(0.014)S(0.014)S(0.195)QPS(0.251)S(0.251)CCS(0.251)DPS(0.023)KPGGNVEGAT(0.002)QS(0.001)LAEQMR;S(0.001)S(0.001)S(0.006)QPS(0.402)S(0.402)CCS(0.121)DPS(0.026)KPGGNVEGAT(0.018)QS(0.023)LAEQMR;S(0.003)S(0.003)S(0.019)QPS(0.381)S(0.292)CCS(0.292)DPS(0.005)KPGGNVEGAT(0.003)QS(0.001)LAEQMR 61.033 0.00072449 28731500.0 52919.9 81591.0 85143.0 74633.0 84094.0 84452.0 76387.0 71647.0 79969.0 75000.0 True False 52165.25252167892 81402.08105243629 78142.87120148445 80121.75978838949 79147.75625516525 80840.1848272273 80341.94509553841 74975.98118023279 70962.04910909761 87963.6500687818 0.5930319226281437 0.9254059033337657 0.8883541228721392 0.9108507858159539 0.899777990036531 0.91901808035496 0.9133539255444297 0.8523518649079078 0.8067201514899615 1.0 16.42461984989596 -4.758289869950401 24.999982674372138 0.8978501760924459 0.5930315048035055 0.7917967646737387 0.04745529614445767 38.35918211723607 304433.64408151223 0.01155147357295174 0.08005127912201428 1.7446572923152407e-05 4.758289869950401 -0.30481867128894036 SSSQPSS(ph)CCSDPSKPGGNVEGATQSLAEQMR ddPTM_PC-9_AZD4547_30min_R2 3 SSSQPSSCCSDPSKPGGNVEGATQSLAEQMR 31 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 S(0.003)S(0.003)S(0.007)QPS(0.161)S(0.445)CCS(0.13)DPS(0.065)KPGGNVEGAT(0.087)QS(0.1)LAEQMR;S(0.002)S(0.001)S(0.003)QPS(0.03)S(0.509)CCS(0.177)DPS(0.223)KPGGNVEGAT(0.037)QS(0.018)LAEQMR;S(0.001)S(0.001)S(0.003)QPS(0.065)S(0.582)CCS(0.167)DPS(0.178)KPGGNVEGAT(0.003)QS(0.001)LAEQMR 58.945 0.0016654 104968800.0 160850.0 172365.0 203333.0 239232.0 222371.0 245568.0 216382.0 267774.0 182552.0 208708.0 True False 211996.95411215848 228078.61546871386 200636.67156457817 184080.75849755516 191498.62505286225 230212.59413987913 235639.57881252273 226395.68113437624 192201.3260327054 201401.1964457712 1.0526102021903343 1.1324590890904949 0.9962039705091876 0.9140003224713726 0.950831615860955 1.143054749438222 1.1700008886291322 1.124102960308555 0.9543206764635932 1.0 17.61971272829419 -6.764830435983684 24.99991983086257 1.0917838495415646 1.0100543896229253 0.14149952467011473 0.08175023945096759 167.27935957523303 1233223.0817414576 0.030616101744417895 0.028089357659945198 1.7185792506646887e-07 6.764830435983684 -0.08172945991863934 SSSQPSS(ph)CCSDPSKPGGNVEGATQSLAEQMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSQPSSCCSDPSKPGGNVEGATQSLAEQMR 31 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 S(0.038)S(0.042)S(0.252)QPS(0.11)S(0.291)CCS(0.106)DPS(0.143)KPGGNVEGAT(0.013)QS(0.005)LAEQMR;S(0.013)S(0.005)S(0.039)QPS(0.206)S(0.503)CCS(0.156)DPS(0.077)KPGGNVEGAT(0.002)QSLAEQMR 70.53399999999999 7.373e-05 17403200.0 50643.0 66625.0 63111.0 65474.0 70324.0 56856.0 65819.0 52224.0 56131.0 49241.0 True False 59215.859655156346 73239.08969071429 64615.80558980032 61805.704049572 56544.51702505799 53874.371270732285 59584.147831705886 50853.17533590186 56951.80968558086 58168.0035084585 1.018014304832475 1.2590958133893013 1.11084791796927 1.062537827013171 0.9720896990531155 0.9261856694617022 1.0243457612060116 0.8742465319186525 0.9790917042098447 1.0 15.827938167162516 -6.039577007680117 2.0554718752392342 0.9558273997026375 1.144606419614964 0.5610307259948517 0.06678155624856805 0.21299823654170436 1.7949935347966024 0.02056605148387826 0.03149152403982801 9.128995485724791e-07 6.039577007680117 0.18877901991232637 SSSQPSS(ph)CCSDPSKPGGNVEGATQSLAEQMR ddPTM_PC-9_Lapatinib_30min_R1 3 SSSQPSSCCSDPSKPGGNVEGATQSLAEQMR 31 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 S(0.001)S(0.001)S(0.009)QPS(0.169)S(0.554)CCS(0.136)DPS(0.126)KPGGNVEGAT(0.003)QSLAEQMR;SSS(0.002)QPS(0.039)S(0.638)CCS(0.141)DPS(0.177)KPGGNVEGAT(0.003)QS(0.001)LAEQMR;S(0.003)S(0.001)S(0.007)QPS(0.063)S(0.575)CCS(0.234)DPS(0.113)KPGGNVEGAT(0.002)QS(0.003)LAEQMR 76.294 2.0977000000000003e-06 130318700.0 167881.2 218655.0 255176.0 236719.0 249872.0 240512.0 222403.0 213715.0 250931.0 201213.0 True False 165487.18330235817 218148.7177816236 234196.4142878453 254128.10493143444 235175.02022725332 230225.86242085556 233917.93911376316 223644.97910496546 222668.508359426 235992.39895053068 0.7012394638059848 0.9243887462127646 0.992389650384198 1.076848686913452 0.9965364192791282 0.9755647361723547 0.9912096328271895 0.9476787392285736 0.9435410180566973 1.0 17.84838086718929 -4.756281229010588 2.5700111968658526 0.9908796718901305 0.6287116531799121 0.863331394174346 0.03453078849498882 0.205658590032126 1.65541576232798 0.009989770774088004 0.16884035150845056 1.752745137629547e-05 4.756281229010588 -0.3621680187102184 SSSQPSSCCS(ph)DPSKPGGNVEGATQSLAEQMR ddPTM_PC-9_AZD4547_30min_R2 1 SSSQPSSCCSDPSKPGGNVEGATQSLAEQMR 31 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 SSS(0.001)QPS(0.084)S(0.06)CCS(0.625)DPS(0.228)KPGGNVEGAT(0.001)QSLAEQMR 88.48100000000001 2.3089999999999998e-09 6113300.0 27215.0 27578.0 30236.0 38112.0 36056.0 32387.0 31131.0 44218.0 32341.0 36525.0 True False 35868.80389283423 36492.04918281668 29835.050884148575 29325.867224530273 31050.246771863243 30361.83577016662 33901.59869126188 37385.12412855552 34050.47923453993 35246.270867344756 1.0176623798821862 1.0353449679871274 0.8464739715710007 0.8320275167521434 0.8809512611625226 0.861419804791221 0.961849235593071 1.0606831079878123 0.9660732439665636 1.0 15.105183004839988 -7.521499004181161 21.532130740674894 1.0102802653027958 0.909987747258198 0.2947228512149753 0.0672476098046483 12.296659082531317 191977.53290172733 0.03457997078362766 0.02043112394043824 3.009546069626867e-08 7.521499004181161 -0.10029251804459782 SSSQPSSCCS(ph)DPSKPGGNVEGATQSLAEQMR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSQPSSCCSDPSKPGGNVEGATQSLAEQMR 31 1 Q13501;Q13501-2;E7EMC7 Q13501 SQSTM1 Sequestosome-1 1 S(0.001)S(0.001)S(0.005)QPS(0.192)S(0.198)CCS(0.523)DPS(0.079)KPGGNVEGAT(0.001)QSLAEQMR 73.936 1.3152000000000001e-06 23238000.0 15677.0 22496.0 25154.0 25733.0 24195.0 32873.0 22467.0 21942.0 26833.0 18325.0 True False 15453.443105190292 22443.911894150107 23085.93521724794 27625.490662771528 22771.897669200196 31467.098420705788 23630.23132812472 22961.50542320919 23810.78497598339 21492.451833472347 0.7190172263698225 1.0442694983359673 1.0741415356480597 1.2853578026750576 1.0595300082857573 1.4640999856376984 1.0994665248626028 1.0683520708162733 1.1078673182787118 1.0 14.39154245264653 -4.535034936299576 1.4752422141058599 1.1620671887406313 0.29432835846829053 0.4980087259578001 0.12830619017237432 1.7489243580829714 2.234037815285087 0.03601155064944219 2.6492521642410947 2.91719233451771e-05 4.535034936299576 -0.8677388302723408 SSSQSGSGPS(ph)SPDSVLRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSQSGSGPSSPDSVLRPR 19 1 O75427;H7C5D9 O75427 LRCH4 Leucine-rich repeat and calponin homology domain-containing protein 4 1 S(0.012)S(0.012)S(0.026)QS(0.097)GS(0.003)GPS(0.421)S(0.421)PDS(0.006)VLRPR 48.224 0.034885 4081400.0 12713.0 14911.0 15106.0 13369.0 25278.0 18803.0 19037.0 16067.0 17157.0 15032.0 True False 14865.059806804558 16391.265536634037 15466.184329824031 12619.978272882794 20324.95735964132 17816.937579210273 17233.677544055434 15645.258274393676 17407.888667144907 17757.182606753464 0.8371294104477495 0.9230780523932925 0.8709818822239225 0.7106971050735902 1.1446048514425522 1.0033651156143477 0.970518686759524 0.8810664743878585 0.9803294279647881 1.0 14.116115078258852 -6.256313673115167 24.99997367306492 0.9897301961821527 0.8442656720728002 0.5015856930849962 0.07833227953192759 431.78438802439103 2105971.9025689745 0.02466969036837689 0.030876089671713586 5.542252741511157e-07 6.256313673115167 -0.1454645241093525 SSSQSGSGPSS(ph)PDSVLRPR ddPTM_PC-9_AZD4547_30min_R2 2 SSSQSGSGPSSPDSVLRPR 19 1 O75427;H7C5D9 O75427 LRCH4 Leucine-rich repeat and calponin homology domain-containing protein 4 1 SSS(0.006)QS(0.018)GS(0.009)GPS(0.309)S(0.654)PDS(0.004)VLRPR;SSSQSGSGPS(0.052)S(0.947)PDS(0.001)VLRPR 134.09 2.5771999999999997e-05 27726000.0 25490.0 35148.0 48298.0 60629.0 55902.0 44551.0 39404.0 58918.0 38618.0 42152.0 True False 33595.289775063204 46508.90364339834 47657.53696264739 46651.920758712375 48140.97223875917 41765.218927245274 42910.87966433729 49813.57690095064 40659.26863979045 40676.271310070275 0.8259186177358881 1.1433915190718102 1.1716299313513714 1.1469075029785905 1.1835148770590693 1.0267710776357568 1.0549364108925539 1.224634788209268 0.9995820002735694 1.0 15.311899816635243 -4.757940854346433 24.984902307184033 1.114453101781037 0.8259182098827226 0.5393111527515789 0.07719761272243769 73.01275923781672 521343.3513677965 0.018540081807243963 0.13200037966815195 1.7460599289644072e-05 4.757940854346433 -0.2885348918983145 SSSQSGSGPSS(ph)PDSVLRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSQSGSGPSSPDSVLRPR 19 1 O75427;H7C5D9 O75427 LRCH4 Leucine-rich repeat and calponin homology domain-containing protein 4 1 SSS(0.001)QS(0.004)GS(0.016)GPS(0.267)S(0.705)PDS(0.008)VLRPR 78.531 0.0014492 6713700.0 12829.0 9266.5 14967.0 13469.0 15343.0 17393.0 15951.0 13651.0 15691.0 13282.0 True False 15000.696315700117 10186.416879834984 15323.870042663582 12714.375597087172 12336.649290647065 16480.880461373425 14440.00580476065 13292.675714430074 15920.451190544429 15689.921459745854 0.9560721099965978 0.6492331338923084 0.9766696463062983 0.810353042856667 0.7862785879647669 1.0504119159332224 0.9203363982291439 0.8472111060934138 1.0146928543517584 1.0 13.937550510063314 -6.746065659808215 24.98196726169989 0.9540940400530515 0.8317819606821187 0.29558845794391075 0.0999572904505709 323.2408844102899 525258.6105729745 0.03175646368844908 0.031645861455391056 1.7944623064197717e-07 6.746065659808215 -0.1223120793709328 SSSQSGSGPSS(ph)PDSVLRPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSQSGSGPSSPDSVLRPR 19 1 O75427;H7C5D9 O75427 LRCH4 Leucine-rich repeat and calponin homology domain-containing protein 4 1 SSSQS(0.002)GS(0.002)GPS(0.321)S(0.552)PDS(0.122)VLRPR 84.15899999999999 0.00064683 11082000.0 25525.0 18259.0 24697.0 18344.0 23291.0 32649.0 26100.0 29549.0 32171.0 18430.0 True False 25161.008819288294 18216.722407329606 22666.50799317691 19693.078953790115 21921.069171867828 31252.678378536282 27451.33029171918 30921.954413927986 28547.56320435142 21615.600943568646 1.1640207868833055 0.8427580826870178 1.0486179890326364 0.911058591671931 1.0141318406597466 1.4458389780662093 1.2699776593482521 1.430538734252877 1.320692553442298 1.0 14.399785325256069 -6.696960361232384 7.626696968852829 1.318412361376484 0.9839099540423368 0.5270329288604311 0.13966167894364204 0.16190296807882126 16.400034223351685 0.04285532096412052 0.04269686158221736 2.0092761941640786e-07 6.696960361232384 -0.33450240733414716 SSSQSGSGPSSPDS(ph)VLRPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSQSGSGPSSPDSVLRPR 19 1 O75427;H7C5D9 O75427 LRCH4 Leucine-rich repeat and calponin homology domain-containing protein 4 1 SSSQS(0.001)GS(0.004)GPS(0.197)S(0.197)PDS(0.601)VLRPR 86.22200000000001 0.0005889 11048000.0 16744.0 18049.0 35204.0 18317.0 18115.0 27941.0 18321.0 21494.0 34095.0 14610.0 True False 16505.227489526456 18007.208649427263 32309.663011369816 19664.093283720755 17049.51131546029 26746.02856365226 19269.57173465853 22492.68970770478 30254.862063733213 17135.319033398697 0.963228490660482 1.0508826018546344 1.8855594662926665 1.1475767241562989 0.9949923478068219 1.5608713506600718 1.1245528429963825 1.3126507690848332 1.7656433477989542 1.0 14.064685432428854 -8.014612950245528 24.64082132813084 1.4349301053740189 1.2592884695599853 0.022570170393623523 0.31831952511765693 1971.2352842156242 3323940.088171217 0.1975350480333565 0.08069767884311368 9.669122217827949e-09 8.014612950245528 -0.17564163581403358 SSSQSTFHIPLS(ph)PVEVKPGNVR ddPTM_PC-9_AZD4547_30min_R2 1 SSSQSTFHIPLSPVEVKPGNVR 22 1 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 SSSQSTFHIPLS(0.999)PVEVKPGNVR 55.707 0.005395399999999999 15151000.0 17233.0 14207.0 54615.0 146620.0 90616.0 75785.0 38130.0 98002.0 46497.0 73308.0 True False 22712.735531332444 18799.134916972802 53890.76941519293 112819.02425641878 78035.53254601611 71046.15196968138 41523.49613240234 82858.0427619226 48954.73649449315 70741.50923321854 0.3210665955182517 0.2657440464691863 0.7617984122663741 1.594806577910012 1.103108109960601 1.0043064212195205 0.5869749823333411 1.1712789797678562 0.6920227886727804 1.0 16.110269378063165 -5.399900266363228 4.1658923444787685 1.0230204245615797 0.2998159203080437 0.5509384719056352 0.25878933422565603 0.16866546028807441 4.837531094643288 0.07169224226350822 0.158343005735577 3.981986044467236e-06 5.399900266363228 -0.723204504253536 SSSQSTFHIPLS(ph)PVEVKPGNVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSQSTFHIPLSPVEVKPGNVR 22 1 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 SSSQSTFHIPLS(1)PVEVKPGNVR 53.037 0.008904700000000002 4256500.0 5585.9 5118.7 15271.0 14741.0 25406.0 26904.0 25573.0 21652.0 30411.0 20960.0 True False 6531.48254344604 5626.850707690205 15635.118555590001 13915.109560966815 20427.876678497007 25493.10687821484 23150.540307513264 21083.65794219032 30855.703343040394 24759.88208073128 0.2637929583892886 0.22725676517131527 0.6314698311005938 0.5620022549217178 0.8250393362896691 1.029613420415042 0.935002042094924 0.8515249738849974 1.2461975078246847 1.0 14.59571682326361 -5.687900129971494 0.6363765471796446 1.0446837419820674 0.06814419055165222 0.8690225460280342 0.11419292234801413 0.4536695349041125 0.2888304886880189 0.06457443438049693 0.2798880619310749 2.0516339167571862e-06 5.687900129971494 -0.9765395514304152 down SSSQSTFHIPLS(ph)PVEVKPGNVR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSQSTFHIPLSPVEVKPGNVR 22 1 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 SSSQSTFHIPLS(0.999)PVEVKPGNVR 57.045 0.0047542 5784500.0 20603.0 11669.0 47096.0 14957.0 40913.0 62921.0 32812.0 44749.0 84765.0 32927.0 True False 20309.197441872537 11641.981147441225 43223.948675817286 16056.987675089342 38506.577778052815 60230.015506014905 34510.84480965099 46828.20190425613 75217.8730849787 38618.38807753038 0.5258944884260767 0.30146212017106344 1.1192582297593772 0.4157860665456386 0.9971047393471449 1.559620131868191 0.8936376303528497 1.2125882056559096 1.9477217157270028 1.0 15.237000327341748 -6.299660575740198 0.8078567712532404 1.3695601997149687 0.4661523198043707 0.4712975966571159 0.35143662745843013 0.6034715733069718 0.853988444532393 0.19415428024297857 0.31560531691657256 5.0157909124282e-07 6.299660575740198 -0.903407879910598 SSSS(ph)ASDGESEGKR ddPTM_PC-9_AZD4547_30min_R2 1 SSSSASDGESEGKR 14 1 K7EJD2;A0A0A0MR03;Q9Y5B0;A0A0J9YWJ4;A0A0J9YWB6;Q9Y5B0-4 K7EJD2 CTDP1 RNA polymerase II subunit A C-terminal domain phosphatase 1 SS(0.002)S(0.18)S(0.45)AS(0.323)DGES(0.045)EGKR 104.09 0.0020591999999999997 0.0 5991.9 3342.2 3407.5 7213.9 7630.8 4669.2 5969.9 6265.9 6019.6 7302.7 True False 7897.1995607375875 4422.500789716798 3362.3143235790526 5550.846808643971 6571.395137195865 4377.234185878963 6501.20953477127 5297.6491310578485 6337.783766743036 7047.034695768882 1.120641504075346 0.6275690387010747 0.4771247012020281 0.7876854660552134 0.9325050068422969 0.6211455420401298 0.9225454131330826 0.7517557894583117 0.8993546988704784 1.0 12.782800601797137 -8.552261814479087 0.6242012332119846 1.0031369084215687 0.7493932210835694 0.13538793203065835 0.17438925492913737 1.7584948064565147 1.5835396403459376 0.18274926657379395 0.07655129982433134 2.8037428916402627e-09 8.552261814479087 -0.25374368733799924 SSSS(ph)DSIHSVR ddPTM_PC-9_AZD4547_30min_R2 1 SSSSDSIHSVR 11 0 Q8WYL5-4;Q8WYL5 Q8WYL5-4 SSH1 Protein phosphatase Slingshot homolog 1 1 S(0.001)S(0.036)S(0.137)S(0.826)DSIHSVR 143.76 9.0075e-05 66980000.0 8303.7 9199.4 76928.0 136520.0 100940.0 68682.0 38267.0 87218.0 71964.0 77690.0 True False 10944.103872310408 12172.926145928035 75907.88445613768 105047.42321297414 86926.22335122795 64387.30368254493 41672.68886699814 73740.46217025557 75767.87012258227 74970.09674699567 0.14597958849171394 0.16237042066263374 1.0125088235154183 1.4011909784174554 1.1594786071115937 0.8588398104891758 0.5558574775171025 0.983598332800746 1.010641221102847 1.0 16.194027643457538 -5.260373588180827 23.306939838016017 0.9966182906017359 0.15417475418531398 0.7380023782809476 0.20105222991075017 19.403196055774995 424269.56660678517 0.059379110541584124 0.13988437035954626 5.490683518548509e-06 5.260373588180827 -0.8424435364164219 SSSS(ph)ELLLTGPGAEEDPLPLIVQDQYVQEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSSELLLTGPGAEEDPLPLIVQDQYVQEAR 31 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 S(0.117)S(0.117)S(0.143)S(0.622)ELLLTGPGAEEDPLPLIVQDQYVQEAR;S(0.122)S(0.122)S(0.146)S(0.607)ELLLT(0.003)GPGAEEDPLPLIVQDQYVQEAR 134.25 1.28e-15 535260.0 955.65 942.17 3103.75 2980.67 2864.93 1398.8 1475.1100000000001 1045.6 874.9 1376.9099999999999 True False 1117.4226700521338 1035.7024110153911 3177.7551710374246 2813.672723362524 2303.5675325720854 1325.444465553334 1335.3769019284357 1018.1541079047757 887.6937573518153 1626.5328833864367 0.6869966672457695 0.6367546709901504 1.953698694625434 1.7298591083535093 1.4162440588204184 0.8148894369683831 0.8209959451592426 0.6259658924232641 0.5457582606652498 1.0 10.667584274098608 -6.829859926906096 5.487711470688925 0.7331430580875063 1.3101194348292082 0.3021667161140824 0.39647818631007553 0.2776025263432452 15.439463602128288 0.15733735343004335 0.13984466713652 1.4795855222599651e-07 6.829859926906096 0.5769763767417019 SSSS(ph)FTPFIDPR ddPTM_PC-9_AZD4547_30min_R2 2 SSSSFTPFIDPR 12 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6;E7EN19 C9J840;O95819-6;E7EN19 MAP4K4 1 S(0.002)S(0.002)S(0.036)S(0.959)FTPFIDPR;S(0.002)S(0.002)S(0.183)S(0.694)FT(0.119)PFIDPR 174.23 0.00045036 13272100.0 32738.0 47789.0 50901.0 89056.0 80242.0 74064.0 67818.0 78419.0 62531.0 60392.0 True False 43148.003007297724 63235.85968517028 50226.01948187741 68525.51510148434 69101.78337774155 69432.76637174231 73853.67061912546 66301.1454393505 65836.26100043341 58277.694461894156 0.7403862387780417 1.0850782665487584 0.8618395073044376 1.1758446474970092 1.1857329638001535 1.191412375057872 1.2672716602990517 1.137676190719978 1.1296991346059777 1.0 15.830656183269907 -5.767743380814827 24.998590856247464 1.1685418705233273 0.9146990167277197 0.5731643519227756 0.1018309840882737 99.2714444005336 393663.7382335982 0.026987165942394274 0.041159435910878645 1.7070907896747639e-06 5.767743380814827 -0.25384285379560756 SSSS(ph)FTPFIDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSSFTPFIDPR 12 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6;E7EN19 C9J840;O95819-6;E7EN19 MAP4K4 1 S(0.003)S(0.003)S(0.149)S(0.697)FT(0.149)PFIDPR;S(0.001)S(0.002)S(0.063)S(0.934)FTPFIDPR 197.73 9.9616e-06 5558000.0 24482.2 25960.5 22676.9 30538.3 35046.2 23862.3 28624.5 24984.5 26664.9 21828.4 True False 28626.552914508797 28537.686873032533 23217.603298622165 28827.338057504425 28179.148691251714 22610.918980821643 25912.980136566435 24328.68334826595 27054.823717465326 25785.716126480675 1.1101709479036233 1.1067246196713427 0.9004056038132995 1.1179576287935689 1.0928200928386511 0.876877681810874 1.00493544602219 0.9434945777318 1.0492174653889617 1.0 14.65428449248141 -6.728608781824464 24.999877451913473 0.9732501750936078 1.0616291577516135 0.28179205340629154 0.07224427015397317 269.74643895864523 205406.0997222899 0.023905930756973087 0.02390429809196723 1.8680617076604047e-07 6.728608781824464 0.0883789826580057 SSSS(ph)FTPFIDPR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSSFTPFIDPR 12 0 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;O95819-6;E7EN19 C9J840;O95819-6;E7EN19 MAP4K4 1 S(0.01)S(0.01)S(0.025)S(0.953)FT(0.001)PFIDPR;S(0.002)S(0.002)S(0.061)S(0.912)FT(0.023)PFIDPR 197.73 9.9616e-06 11803600.0 77574.0 76567.0 82751.0 72176.0 64129.0 65175.0 49456.0 49290.0 72314.0 47887.0 True False 76467.7805346706 76389.7138157626 75947.5322080974 77484.06381207792 60357.05830246496 62387.61718034558 52016.5896899335 51580.19334199165 64169.23581982118 56164.204144583375 1.3615038564032667 1.3601138835531748 1.3522408688029453 1.3795987140245214 1.0746534954379114 1.110807464123257 0.9261519945342289 0.9183819859569075 1.1425290680631826 1.0 15.777363311479823 -6.379778227161072 2.2611352801727085 1.0067146604613884 1.368040339390588 0.8512722894308333 0.06838512061491223 0.11164192984858966 1.1203830452098358 0.023845723464289575 0.0281681238028459 4.170823125298081e-07 6.379778227161072 0.36132567892919965 SSSS(ph)GSDDYAYTQALLLHQR ddPTM_PC-9_AZD4547_30min_R2 1 SSSSGSDDYAYTQALLLHQR 20 0 F6SS63;Q8N5C8-2;Q8N5C8 F6SS63 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 1 S(0.002)S(0.002)S(0.11)S(0.885)GS(0.002)DDYAYTQALLLHQR 172.42 8.0452e-09 15434000.0 10659.0 14988.0 20163.0 30208.0 22861.0 19632.0 21168.0 29286.0 26493.0 24495.0 True False 14048.340279027017 19832.5778936854 19895.625445729835 23244.01230894759 19687.14475958415 18404.407936514992 23051.910992150344 24760.521625330788 27893.365893468548 23637.43750569773 0.5943258559918226 0.8390324834874685 0.841699758737979 0.9833558440226312 0.8328798227319956 0.778612653426526 0.9752288498528554 1.0475129387169122 1.1800503284988038 1.0 14.528786023431978 -7.532279289755466 2.516612582759753 1.0890147763178244 0.8230224189606276 0.5896259877778673 0.09966700548805164 0.21728501613150197 2.75687891960402 0.056129053909411926 0.03023474035540121 2.935761090787129e-08 7.532279289755466 -0.26599235735719684 SSSS(ph)PELQTLQDILGDPGDKADVGR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSSPELQTLQDILGDPGDKADVGR 25 1 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4;A0A2R8Y670 P49815 TSC2 Tuberin 1 S(0.239)S(0.239)S(0.239)S(0.277)PELQT(0.004)LQDILGDPGDKADVGR;S(0.082)S(0.082)S(0.372)S(0.465)PELQTLQDILGDPGDKADVGR 123.18 8.1058e-10 26487000.0 35155.0 24888.5 33665.9 27644.7 26024.5 24204.7 23498.8 24284.5 31069.8 20301.5 True False 34653.68325336256 24830.872207394896 30898.019656132103 29677.783458015772 24493.79007613559 23169.521404911557 24715.452883488542 25412.84652492588 27570.39194450148 23810.587224951643 1.4553896939193585 1.0428500554313953 1.2976588676382321 1.2464112362132658 1.0286932382107739 0.9730764380574243 1.0380026603287076 1.0672918851113085 1.1579047456507017 1.0 14.53931558084139 -6.258572074298493 24.15530585852933 1.043663888119516 1.2476741949558807 0.5076907784303022 0.10409287694158362 138.13051226817333 1163661.6562795874 0.03022788476778486 0.03729017539239306 5.513506941683871e-07 6.258572074298493 0.20401030683636479 SSSS(ph)PLVVVSVK ddPTM_PC-9_AZD4547_30min_R2 2 SSSSPLVVVSVK 12 0 Q96B01-3;Q96B01-2;Q96B01 Q96B01-3 RAD51AP1 RAD51-associated protein 1 1 S(0.011)S(0.011)S(0.121)S(0.858)PLVVVSVK;SSS(0.021)S(0.978)PLVVVSVK 188.96 0.00023994 12052500.0 78480.0 94949.0 98819.0 100435.0 106178.0 113544.0 87095.0 124750.0 90214.0 87238.0 True False 103435.00751459235 125639.40742110579 97508.59549281244 77281.26245528186 91437.01746568926 106444.07573062641 94846.28627462823 105472.75396981573 94982.5278644688 84183.8241731806 1.228680313949729 1.4924411982359451 1.1582818486865183 0.9180060803165822 1.086158990325595 1.2644243330126301 1.1266568988302683 1.2528862285091746 1.1282752808790606 1.0 16.36125542724659 -5.399171906451988 6.830416407594079 1.1210245380143933 1.3582938457476599 0.4248449272933933 0.11405881491535629 0.23012704291808242 11.764146544443504 0.03063372781698484 0.064310541270596 3.988669878964408e-06 5.399171906451988 0.2372693077332666 SSSS(ph)PLVVVSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSSPLVVVSVK 12 0 Q96B01-3;Q96B01-2;Q96B01 Q96B01-3 RAD51AP1 RAD51-associated protein 1 1 SSS(0.019)S(0.981)PLVVVSVK;S(0.005)S(0.001)S(0.133)S(0.861)PLVVVSVK 177.42 0.00063856 8563300.0 84978.0 99238.0 95733.0 79689.0 90488.0 73775.0 88097.0 58715.0 58199.0 54858.0 True False 99363.097007995 109089.6927989059 98015.63778942435 75224.28368522385 72757.52597354315 69906.10912653504 79751.8143929532 57173.793463684866 59050.05027330923 64803.32114431094 1.5333025414966415 1.6833966357368222 1.5125094834437989 1.1608090813386926 1.1227437836329242 1.0787426923823962 1.230674801610142 0.8822664094076933 0.911219505892457 1.0 15.983780132098342 -5.795600967341499 2.0422077264150644 1.0411572147588188 1.6207420996872557 0.8546381823367009 0.10004695572833384 0.12043843851187043 1.0258817987242552 0.0329964015503161 0.06249260734125244 1.6010283885549585e-06 5.795600967341499 0.5795848849284368 SSSS(ph)PLVVVSVK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSSPLVVVSVK 12 0 Q96B01-3;Q96B01-2;Q96B01 Q96B01-3 RAD51AP1 RAD51-associated protein 1 1 SSS(0.078)S(0.921)PLVVVSVK;S(0.002)S(0.002)S(0.018)S(0.978)PLVVVSVK 215.02 9.3576e-11 9976800.0 90669.0 102796.0 104689.0 83770.0 86671.0 87022.0 82439.0 80462.0 81469.0 61316.0 True False 89376.04343334158 102557.98217776752 96081.87453122642 89930.72524852803 81573.18218174214 83300.27191819003 86707.28804287505 84200.55826097248 72293.10331339735 71914.38890156568 1.2428116931602784 1.4261121278266844 1.3360591113795113 1.2505247784504239 1.1343096065711848 1.158325519976385 1.2057015204781545 1.1708443824256611 1.0052661841060773 1.0 16.133992838949002 -6.6892172890402115 0.3101850465649101 0.9869040159028495 1.4289402182221913 0.7184682076734195 0.06677701147150737 1.3523725477501407 0.26223640889221816 0.09379439093920117 0.21365876961580552 2.0454210023292514e-07 6.6892172890402115 0.4420362023193418 SSSS(ph)SGVPYSPAIPNKR ddPTM_PC-9_AZD4547_30min_R2 1 SSSSSGVPYSPAIPNKR 17 1 A0A0A0MRE1;B4DJ07;A0A0A0MSB8;Q9UPT5-4;Q9UPT5-2;Q9UPT5-5;Q9UPT5-1;Q9UPT5-6;Q9UPT5 A0A0A0MRE1 EXOC7 Exocyst complex component 7 1 S(0.038)S(0.038)S(0.12)S(0.401)S(0.332)GVPY(0.002)S(0.069)PAIPNKR 57.17100000000001 0.021287999999999998 18592000.0 38851.0 46466.0 63796.0 87323.0 79586.0 94175.0 79732.0 104490.0 70282.0 76317.0 True False 51204.80984899885 61485.225807845345 62950.02335643414 67192.03147690122 68536.8576543575 88286.2223625357 86827.99353864948 88343.47144133065 73996.96303645322 73645.16505908687 0.6952908559294597 0.834884757994834 0.8547746930287708 0.9123753259700323 0.9306362148739721 1.1988054109418051 1.1790046701502506 1.1995827746526342 1.0047769324311258 1.0 16.168303192329304 -6.285540284246772 1.3434107890449303 1.1310912619641666 0.7903291003767761 0.725051498819486 0.08479457511632055 0.2191309977097583 0.8010509054198289 0.033561378022169755 0.04635438526087332 5.181550268027264e-07 6.285540284246772 -0.3407621615873906 SSSS(ph)SQESLNRPFSSK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSSSQESLNRPFSSK 16 1 E3W994;J3KR49;O75122;A0A0U1RQI6;B3KR06;E7ENG2;O75122-2;E7ERI8;E7EW49;O75122-3 E3W994;E7ERI8 CLASP2 CLIP-associating protein 2 1 S(0.027)S(0.027)S(0.027)S(0.822)S(0.098)QESLNRPFSSK;SSS(0.014)S(0.493)S(0.493)QESLNRPFSSK 174.59 6.0961e-05 38705000.0 119234.0 108179.0 113105.0 105229.0 111118.0 104628.0 91190.0 89004.0 107958.0 69560.0 True False 117533.70129516213 107928.5181719982 103805.9434979258 112967.89169365379 104582.25770639349 100153.30433978059 95911.37200390322 93139.45076507636 95798.63319186124 81583.3533171261 1.4406578856631687 1.3229232899077428 1.272391232736136 1.3846929195779871 1.281906828466187 1.2276193643385858 1.1756242922631788 1.1416477379034675 1.174242407265099 1.0 16.31598718693194 -6.91675622767948 0.19087374160813744 0.9286188406989943 1.5531190286587633 0.879438200574671 0.04205936292581602 1.8726708274348454 0.19235464286547987 0.17509781638298325 0.3682335442679177 1.2112778409096658e-07 6.91675622767948 0.624500187959769 SSSS(ph)SQESLNRPLSAK ddPTM_PC-9_AZD4547_30min_R2 1 SSSSSQESLNRPLSAK 16 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 S(0.03)S(0.03)S(0.145)S(0.558)S(0.176)QES(0.057)LNRPLS(0.004)AK 59.181999999999995 0.023843 83207000.0 26318.0 26702.0 37267.0 68582.0 53273.0 51653.0 55443.0 63901.0 48468.0 65311.0 True False 34686.57655159331 35332.89931393032 36772.81523017477 52771.47948133753 45876.96350891588 48423.12974453999 60377.319592677166 54026.56874889927 51029.919530616855 63024.48176912126 0.550366707951067 0.560621814287438 0.5834687441760378 0.8373171504155521 0.7279228995008289 0.7683225372947822 0.957997874760137 0.8572314635892729 0.8096840798716235 1.0 15.943624729845599 -4.305925218019912 0.2602871115235153 0.9731355312118052 6.54257576132577e-14 0.7923079390524103 0.06917271511627568 5.471830773618733 0.25686061659800175 0.09538058068865427 1.7790236509780262 4.943958105982487e-05 4.305925218019912 -0.9731355312117398 SSSS(ph)SQESLNRPLSAK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSSSQESLNRPLSAK 16 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 SSS(0.007)S(0.896)S(0.097)QESLNRPLSAK 127.2 0.00012272 20450000.0 90738.0 80076.0 106180.0 95568.0 87897.0 92415.0 75394.0 84782.0 97419.0 72713.0 True False 89444.05948068875 79890.58894185466 97450.29026665296 102596.38952550212 82727.07127215093 88462.62587988701 79297.53241432473 88721.2812319076 86446.64635245125 85281.34516601765 1.0488115461425653 0.9367885647949293 1.142691758402098 1.203034372004536 0.9700488554807115 1.0373033599279695 0.9298344469116405 1.0403363251270652 1.0136641980044416 1.0 16.379942573850073 SSSS(ph)TPTSPKPLLQSPKPSLAAR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSSTPTSPKPLLQSPKPSLAAR 23 2 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(0.016)S(0.016)S(0.069)S(0.273)T(0.237)PT(0.207)S(0.181)PKPLLQSPKPSLAAR 54.225 0.0033522 10531000.0 14022.0 19696.0 19306.0 22253.0 28221.0 28697.0 30199.0 34831.0 36312.0 23236.0 True False 13822.043708680125 19650.395122118636 17718.735203315126 23889.55985383185 26561.096264620744 27469.69620597432 31762.556455158174 36449.375416817005 32222.160177688245 27252.31163997619 0.5071879366154276 0.7210542496987168 0.6501736600327019 0.8766067322813252 0.9746364497629806 1.0079767385926723 1.1654995317375552 1.3374782990280252 1.1823642927384488 1.0 14.73409098925857 -6.16588492332134 0.7824803749456216 1.2014499685503577 0.5572594871374031 0.8447873277359659 0.09652103798722447 0.25996334429521434 0.33493542188120345 0.052222704361199565 0.10225043445034593 6.825195200049386e-07 6.16588492332134 -0.6441904814129545 SSSSAS(ph)DGESEGKR ddPTM_PC-9_AZD4547_30min_R2 1 SSSSASDGESEGKR 14 1 K7EJD2;A0A0A0MR03;Q9Y5B0;A0A0J9YWJ4;A0A0J9YWB6;Q9Y5B0-4 K7EJD2 CTDP1 RNA polymerase II subunit A C-terminal domain phosphatase 1 SSS(0.009)S(0.078)AS(0.876)DGES(0.037)EGKR 139.21 0.00014561 3110600.0 7655.6 9152.4 9214.2 8310.1 8982.9 9713.2 8021.0 8630.8 10761.0 9412.2 True False 10089.921553627843 12110.734315063128 9092.013687548677 6394.334834765141 7735.779391140737 9105.832068508422 8734.85346126407 7297.108176053572 11329.80449098309 9082.681742850717 1.1108967416556192 1.3333875013947167 1.001027443761894 0.7040139703010442 0.8517065344967998 1.0025488425459725 0.9617042310372228 0.8034089911602782 1.2474074080489674 1.0 13.148902613663557 -5.423699096039446 5.752735007504325 0.9250315844906365 1.2172197503325697 0.36824990628128984 0.14533617799703047 0.21630703987892058 10.197578075683353 0.037710000734760635 0.07967206860768059 3.7696489127752874e-06 5.423699096039446 0.2921881658419332 SSSSAS(ph)DGESEGKR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSSASDGESEGKR 14 1 K7EJD2;A0A0A0MR03;Q9Y5B0;A0A0J9YWJ4;A0A0J9YWB6;Q9Y5B0-4 K7EJD2 CTDP1 RNA polymerase II subunit A C-terminal domain phosphatase 1 SSS(0.002)S(0.006)AS(0.92)DGES(0.072)EGKR 140.03 0.00016462 2094600.0 3873.0 6856.1 6716.7 3000.5 5535.2 4160.4 5340.6 6065.9 5499.2 6679.2 True False 3817.770309778786 6840.225121687529 6164.478853211783 3221.166779374578 5209.630418621908 3982.469390366087 5617.110136243506 6347.743858656663 4879.822186856772 7833.69082052543 0.48735269201276904 0.8731803792619854 0.7869188348689912 0.4111940148230823 0.6650288526797489 0.5083771470698623 0.7170451661847369 0.8103132998336664 0.6229275955174175 1.0 12.935476473903394 -9.607413333879707 0.574968137778486 1.0268072783414044 0.642894753787718 0.35234933671796664 0.14195233043130345 5.995671657849153 2.193001720327952 0.5234085796783258 0.062398970927764884 2.469372834194364e-10 9.607413333879707 -0.3839125245536864 SSSSDEEY(ph)IYMNK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSSDEEYIYMNK 13 0 Q8N4X5-2;Q8N4X5;Q8N4X5-4;F6QUH3 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 SSSSDEEY(0.999)IYMNK;SSSSDEEY(1)IYMNK 192.3 2.4622e-36 0.0 10422.1 13049.3 12441.8 9282.3 12817.0 12997.4 12039.5 8840.0 12157.8 8225.2 True False 10273.47894282094 13019.085147596608 11418.883230736876 9964.951306845069 12063.129259191524 12441.531500419234 12662.846400274064 9250.738672006613 10788.4605366903 9646.914860609917 1.06494968508216 1.3495594535363702 1.1836823892125579 1.032967684573827 1.2504649863188328 1.2896901942423311 1.312631715241806 0.9589323432073644 1.1183327201053177 1.0 13.23585191855193 -7.766900831110288 24.999581953813205 1.0289743878003683 1.2137770414210494 0.40986565377891904 0.10236972105294984 140.9679903452374 645259.9021734999 0.05480368998028363 0.027510418965155495 1.7104058327922662e-08 7.766900831110288 0.18480265362068105 SSSSGDQSSDSLNS(ph)PTLLAL ddPTM_PC-9_AZD4547_30min_R2 1 SSSSGDQSSDSLNSPTLLAL 20 0 P15408;P15408-3;P15408-2 P15408 FOSL2 Fos-related antigen 2 1 SSSSGDQSSDS(0.001)LNS(0.953)PT(0.046)LLAL 79.88600000000001 0.0015313 827220.0 1296.4 698.41 2897.9 3866.3 2649.6 1817.5 1096.9 2308.0 1063.3 2176.2 True False 1708.6282332048613 924.1573743480664 2859.4719525457776 2974.9842687395426 2281.748775425141 1703.8514376841874 1194.521975023134 1951.3516325638004 1119.5038672300261 2100.0119003837285 0.8136278812956484 0.4400724463414698 1.3616455944955719 1.4166511476415602 1.0865408786532136 0.8113532296521024 0.5688167647073156 0.9292097974336413 0.5330940586696021 1.0 11.03618178806584 -6.8661984258552256 5.190865870506879 0.7445549725540179 1.0309993161678472 0.1637726858354961 0.2886981019348436 0.41219212554867923 17.358670410114396 0.11222740162527602 0.09914633651124734 1.3608227907949224e-07 6.8661984258552256 0.2864443436138293 SSSSGDQSSDSLNS(ph)PTLLAL ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSGDQSSDSLNSPTLLAL 20 0 P15408;P15408-3;P15408-2 P15408 FOSL2 Fos-related antigen 2 1 SSSSGDQSSDSLNS(0.82)PT(0.18)LLAL 89.43 0.0032801 0.0 1077.1 2136.5 2471.6 2818.4 3978.0 2080.6 981.82 1007.7 2118.6 2214.5 True False 1259.4317563052925 2348.597600363399 2530.532317595197 2660.4941853760856 3198.5394563119366 1971.48967331303 888.8149018387627 981.2489427464061 2149.580517002576 2615.9713200276456 0.4814394357702602 0.8977918000792834 0.9673394728075438 1.0170196305317176 1.2226966831876944 0.7536358132902601 0.3397647730439834 0.3750992739232463 0.8217140992890776 1.0 11.353131008724114 -6.999939928566812 24.999925003759195 0.5770167153273974 0.9308672414288952 0.20722645512271076 0.25156450947969883 2.7201295618013277 1131302.4270367566 0.08996813529045453 0.07855376627874339 1.000138329153168e-07 6.999939928566812 0.3538505261014978 SSSSGDQSSDSLNS(ph)PTLLAL ddPTM_PC-9_Lapatinib_30min_R1 3 SSSSGDQSSDSLNSPTLLAL 20 0 P15408;P15408-3;P15408-2 P15408 FOSL2 Fos-related antigen 2 1 SSSSGDQSSDSLNS(0.92)PT(0.08)LLAL;SSSSGDQSSDSLNS(0.971)PT(0.029)LLAL;SSSSGDQSSDSLNS(0.807)PT(0.193)LLAL 124.38 6.380100000000001e-05 0.0 10959.2 9310.3 12123.0 7432.1 10392.4 9044.2 3851.2 5591.299999999999 8774.099999999999 9544.5 True False 10802.91979832886 9288.742572373125 11126.293736133293 7978.681426758806 9781.139464244523 8657.400649059937 4050.596291933677 5851.092210044182 7785.868462630933 11194.254107753171 0.9650415020369001 0.8297777130090085 0.9939289950928657 0.7127479285317232 0.8737642874722737 0.7733789643977974 0.36184601965826585 0.5226870994461078 0.6955236488010772 1.0 13.45047078171086 -7.01388125405269 19.810817809845542 0.5998627866530637 0.8654695091999197 0.27806010788066515 0.16821173222198735 45.91554184630348 65528.76276626371 0.06004286252997063 0.0486928326836521 9.685426415543325e-08 7.01388125405269 0.265606722546856 SSSSLLAS(ph)PGHISVK ddPTM_PC-9_AZD4547_30min_R2 1 SSSSLLASPGHISVK 15 0 A0A499FIX8;H7BXI1;A0A087WXU3;A0FGR8-5;A0FGR8-2;A0FGR8;A0FGR8-6 A0A499FIX8 ESYT2 Extended synaptotagmin-2 1 SSS(0.001)SLLAS(0.996)PGHIS(0.002)VK 89.04899999999999 0.0026388 9174300.0 14032.0 13088.0 66986.0 121160.0 85221.0 63115.0 34115.0 111960.0 52820.0 72341.0 True False 18493.884116268593 17318.440050210476 66097.72187212507 93228.43390333996 73389.53517153772 59168.40907259284 37151.168910487926 94659.15458485429 55611.95736583281 69808.36360888687 0.26492361602806935 0.24808546075137872 0.9468453127256886 1.3354908936938845 1.0513000359486289 0.8475833841929576 0.5321879355120487 1.355985868902445 0.7966374584771558 1.0 16.091112272921706 -5.271976475337552 6.215243156762734 0.9916166806819476 0.25198130960927756 0.6166411956200979 0.22926760029498858 0.09138804869054731 16.883444452563488 0.0613507450512394 0.14169659512580385 5.345933162159786e-06 5.271976475337552 -0.7396353710726701 SSSSPELQT(ph)LQDILGDPGDKADVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSPELQTLQDILGDPGDKADVGR 25 1 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4;A0A2R8Y670 P49815 TSC2 Tuberin 1 S(0.064)S(0.064)S(0.261)S(0.261)PELQT(0.349)LQDILGDPGDKADVGR 52.909 0.0091601 2680900.0 10749.0 10862.0 11783.0 15189.0 15916.0 15764.0 14136.0 18882.0 15145.0 13552.0 True False 12568.59339757273 11940.307575542822 12063.951407276341 14338.009573402402 12797.374053961988 14937.308089064021 12796.935744222705 18386.367507132723 15366.466973474946 16008.870322427023 0.7851018306997736 0.7458557246738078 0.7535791823096851 0.8956290659257892 0.7993926989360386 0.9330644691485921 0.7993653197562179 1.1485112401326054 0.9598720374383864 1.0 13.966583886170996 -7.154481616613646 0.7448203792245325 1.0367475830749604 0.7717190041085067 0.5652933851914246 0.08125428377188827 0.47464577007227565 0.5313104367965007 0.06384032359073391 0.04373271768899813 7.006778414482193e-08 7.154481616613646 -0.2650285789664537 SSSSPLVVVS(ph)VKSPNQSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSPLVVVSVKSPNQSLR 19 1 Q96B01-3;Q96B01-2;Q96B01 Q96B01-3 RAD51AP1 RAD51-associated protein 1 1 SSSSPLVVVS(0.591)VKS(0.399)PNQS(0.01)LR 121.14 1.8922999999999998e-05 12457000.0 55809.0 32594.0 50149.0 67010.0 88821.0 96458.0 71960.0 98428.0 73914.0 61361.0 True False 65256.36142200544 35829.71691375831 51344.742351141605 63255.64694935118 71417.16265688359 91399.57267539567 65143.42785471613 95844.36929308629 74994.85241845 72485.26356659124 0.9002707338168854 0.4943034646048025 0.70834732226602 0.872669061777489 0.9852645785204823 1.2609400611674415 0.8987127127553277 1.3222600646962586 1.0346220559652548 1.0 16.14540010101666 -6.118638635117469 1.8660257282241532 1.1097636762020942 0.6786976744232754 0.5763467963236857 0.14888854877308796 0.22214215190189476 1.5318724748755952 0.04754835554113208 0.06985856112529462 7.609591874816891e-07 6.118638635117469 -0.4310660017788187 SSSSPLVVVSVKS(ph)PNQSLR ddPTM_PC-9_AZD4547_30min_R2 2 SSSSPLVVVSVKSPNQSLR 19 1 Q96B01-3;Q96B01-2;Q96B01 Q96B01-3 RAD51AP1 RAD51-associated protein 1 1 SSSSPLVVVS(0.097)VKS(0.54)PNQS(0.364)LR;SSSSPLVVVS(0.296)VKS(0.409)PNQS(0.296)LR 98.00200000000001 0.00027159 32364000.0 87409.0 68053.0 90708.0 155734.0 119839.0 95463.0 93034.0 100515.0 85927.0 129331.0 True False 115203.2437798546 90049.80140105232 89505.15265244571 119831.9323663151 103201.42342171383 89493.68351892462 101313.84576926069 84982.71635491804 90468.92579655275 124803.16105529241 0.9230795342500605 0.7215346201139643 0.7171705579860403 0.9601674457045614 0.8269135376786794 0.7170786602053743 0.8117890998319739 0.6809340054877902 0.7248929036057963 1.0 16.929294950151714 -6.713723941867381 24.828517552323557 0.7685503656392124 0.8247484191581906 0.02295339130428331 0.10858570647491951 359.952596135454 187298.18108611327 0.03519928083648928 0.03519920193695235 1.933196757926706e-07 6.713723941867381 0.05619805351897822 SSSSPLVVVSVKS(ph)PNQSLR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSSPLVVVSVKSPNQSLR 19 1 Q96B01-3;Q96B01-2;Q96B01 Q96B01-3 RAD51AP1 RAD51-associated protein 1 1 SSSSPLVVVS(0.048)VKS(0.925)PNQS(0.027)LR;SSSSPLVVVS(0.061)VKS(0.691)PNQS(0.248)LR 93.729 0.00037808 19230300.0 114626.0 78667.0 86522.0 75897.0 78063.0 87492.0 62087.0 49512.0 80239.0 65566.0 True False 112991.41222016631 78484.85139478614 79408.4951445785 81478.7185649699 73471.48781776302 83750.17111381354 65301.56106597582 51812.50827244247 71201.63886587149 76898.99573879664 1.4693483462900483 1.0206225795376598 1.0326337084336692 1.0595550407671022 0.9554284436603585 1.0890931709731078 0.8491861361595161 0.6737735359826335 0.9259111667429649 1.0 16.230677137006793 -1.5228787452803376 0.5758403367689546 0.8979055093145206 27.939051316230277 0.6441146890623233 0.11464783494417158 103.58599881186817 0.8720411151062547 0.0578033800123732 3497.268608379696 0.029999999999999995 1.5228787452803376 27.041145806915758 SSSSRGS(ph)SYSSIPK ddPTM_PC-9_AZD4547_30min_R2 1 SSSSRGSSYSSIPK 14 1 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 1 S(0.038)S(0.085)S(0.085)S(0.159)RGS(0.47)S(0.159)YS(0.003)S(0.001)IPK 64.327 0.019578 6914900.0 16447.0 12476.0 22188.0 34824.0 27121.0 27591.0 12879.0 27922.0 24590.0 26488.0 True False 21676.803881148066 16508.623018522754 21893.77262261834 26795.864825436674 23355.717292536712 25865.73040833257 14025.206050071065 23607.296483728973 25889.77719852005 25560.663182319735 0.8480532655405386 0.645860512333723 0.8565416502089126 1.048324319064277 0.913736749549277 1.0119350278135133 0.5487027449183038 0.9235791855376467 1.0128758011422787 1.0 14.641637647658765 -5.51040405181492 24.142318114912342 0.9107800414809616 0.7480178903589277 0.1932340924691719 0.1411560270701405 630.9367667493392 1221050.2660738542 0.03845086397500178 0.07409752596147795 3.087421670893704e-06 5.51040405181492 -0.16276215112203385 SSSSRGS(ph)SYSSIPK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSSRGSSYSSIPK 14 1 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 1 S(0.026)S(0.026)S(0.026)S(0.141)RGS(0.594)S(0.167)Y(0.002)S(0.014)S(0.004)IPK 59.501999999999995 0.027999999999999997 7316600.0 25566.0 19196.0 18045.0 27025.0 22292.0 21372.0 14586.0 16541.0 19572.0 15686.0 True False 25201.424151769814 19151.552841398723 16561.40975571436 29012.508652757195 20980.82838775826 20457.96938056531 15341.19171015387 17309.555245889307 17367.595257703088 18397.304199718816 1.3698433139000328 1.040997780625459 0.9002085075033703 1.5769978219526652 1.1404294977129819 1.1120090834220153 0.8338825919065003 0.940874546508497 0.9440293571907418 1.0 14.167206759819178 -7.050060584136481 3.5043665049853017 0.9255849654153127 1.1973761200182471 0.3551495430549705 0.17483198065744185 0.29418475259382015 7.2773323949108715 0.07117756125603703 0.05611081584300135 8.911266171840259e-08 7.050060584136481 0.27179115460293446 SSSSS(ph)QESLNRPFSSK ddPTM_PC-9_AZD4547_30min_R2 4 SSSSSQESLNRPFSSK 16 1 E3W994;J3KR49;O75122;A0A0U1RQI6;B3KR06;E7ENG2;O75122-2;E7ERI8;E7EW49;O75122-3 E3W994;E7ERI8 CLASP2 CLIP-associating protein 2 1 SSSS(0.004)S(0.995)QESLNRPFSSK;SSSS(0.001)S(0.999)QESLNRPFSSK;SSSS(0.003)S(0.997)QESLNRPFSSK;SSSS(0.003)S(0.99)QES(0.007)LNRPFSSK 285.43 8.0759e-96 63695000.0 117225.0 123620.0 187708.0 267208.0 224464.0 203230.0 191755.0 249968.0 183364.0 189843.0 True False 154500.11156852852 163577.74747914265 185218.86927377162 205607.32392244687 193301.04813067228 190521.99597279614 208820.82352134312 211341.1892932012 193056.24669497495 183196.65435371184 0.8433566219513119 0.8929079412297046 1.0110384926361993 1.122331216406742 1.0551559951387055 1.0399862194259328 1.1398724734249608 1.1536301797583517 1.053819718357009 1.0 17.483033630757134 -5.318540911218045 2.207266058352971 1.087003563867882 0.8484181637273565 0.7697099246053325 0.04604306668279443 0.14741808166311954 1.34515641771533 0.013059879101371194 0.04306720672225921 4.802408386722458e-06 5.318540911218045 -0.23858540014052565 SSSSS(ph)QESLNRPFSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSSSSQESLNRPFSSK 16 1 E3W994;J3KR49;O75122;A0A0U1RQI6;B3KR06;E7ENG2;O75122-2;E7ERI8;E7EW49;O75122-3 E3W994;E7ERI8 CLASP2 CLIP-associating protein 2 1 SSSS(0.005)S(0.995)QESLNRPFSSK;SSS(0.003)S(0.028)S(0.963)QES(0.005)LNRPFSSK;SSSS(0.051)S(0.949)QESLNRPFSSK;SSS(0.004)S(0.136)S(0.859)QESLNRPFSSK 157.37 0.00021810000000000002 57059000.0 142279.0 160688.0 190341.0 218642.0 255719.0 236991.0 230261.0 228008.0 227103.0 183595.0 True False 166364.02456165658 176640.04269000396 194879.45131226198 206392.1975869277 205612.69764420093 224562.77476118834 208449.01113472428 222023.03159444514 230423.95173833496 216879.32016277954 0.7670810865544556 0.8144623588704822 0.8985617031904864 0.9516453548084682 0.9480511903572807 1.0354273270159735 0.9611290323958602 1.0237169289713974 1.062452388569779 1.0 17.726532970411704 -4.894637609003179 0.5431569981428829 1.02492007461896 0.5966632167023252 0.9098278668420455 0.027248962403761876 0.9865532153462576 0.24260038924547753 0.015801647491741892 0.26437914411795793 1.2745661814529947e-05 4.894637609003179 -0.4282568579166347 SSSSS(ph)QESLNRPFSSK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSSSQESLNRPFSSK 16 1 E3W994;J3KR49;O75122;A0A0U1RQI6;B3KR06;E7ENG2;O75122-2;E7ERI8;E7EW49;O75122-3 E3W994;E7ERI8 CLASP2 CLIP-associating protein 2 1 SSSSS(0.999)QES(0.001)LNRPFSSK;S(0.001)S(0.001)S(0.005)S(0.036)S(0.958)QESLNRPFSSK 201.57 7.555e-12 41738000.0 136286.0 104237.0 143418.0 114662.0 114878.0 102304.0 114392.0 105185.0 120606.0 85360.0 True False 134342.53664820862 103995.64563080242 131626.72564948958 123094.62598121876 108121.1018988379 97928.69640227193 120314.65803564526 110072.27909672148 107022.08224251673 100114.36226494948 1.341890749827436 1.038768497127128 1.3147636629911663 1.229540129871204 1.079975934049291 0.9781683085899978 1.2017722064416327 1.0994654174135245 1.068998291766432 1.0 16.61128943044978 -1.5228787452803376 0.144037442806084 0.9800750137082501 1.9698783675139973 0.3592055978879616 0.097792437094502 90.8208321582258 0.8689993238918094 0.3972604469094189 18.60874405141444 0.029999999999999995 1.5228787452803376 0.9898033538057471 SSSSS(ph)QESLNRPLSAK ddPTM_PC-9_AZD4547_30min_R2 1 SSSSSQESLNRPLSAK 16 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 S(0.002)S(0.002)S(0.015)S(0.058)S(0.92)QES(0.004)LNRPLSAK 77.031 0.0051736 76849000.0 60986.0 53941.0 83731.0 130500.0 92475.0 92716.0 97931.0 111150.0 94464.0 119600.0 True False 80378.27941239717 71376.37337625334 82620.67223113646 100415.24120490131 79636.44248469186 86918.45386317886 106646.66928251486 93974.32147290591 99457.17418792192 115412.84040340668 0.6964413936217847 0.6184439541282315 0.7158707119792688 0.8700525942686818 0.6900137125672994 0.7531090436676685 0.9240450967998786 0.8142449414158257 0.861751377405544 1.0 16.816444216234594 -3.3780537762819574 0.08942323927781667 1.1800461337356367 2.2418878481701302e-09 0.6744764079799852 0.06481603502066625 64.03781711866594 0.6207731805923568 1.559881069009032 9.596703552432649 0.0004187417114391352 3.3780537762819574 -1.180046131493749 SSSSS(ph)QESLNRPLSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSSQESLNRPLSAK 16 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 S(0.001)S(0.001)S(0.006)S(0.106)S(0.884)QES(0.002)LNRPLSAK 110.57 0.0026829999999999996 12629000.0 36097.0 43804.0 54457.0 72993.0 85366.0 68168.0 65430.0 73434.0 67705.0 50041.0 True False 42207.50915175207 48152.57162944923 55755.46140932254 68903.4388564988 68639.14510495838 64593.15007709441 59231.99672782204 71506.43530975457 68695.05753972405 59113.03717566198 0.7140135436845689 0.8145846319206655 0.9432007569436507 1.1656216995202495 1.1611507103075815 1.0927056562014834 1.002012408054869 1.2096559190025038 1.1620965665422986 1.0 15.851188726440055 -5.401217348247711 2.0903189597504275 1.1185552062433375 0.7387789251386628 0.8028854742534878 0.069436161815082 0.1408690783157507 1.1653065068379653 0.02016979088803277 0.06062731941087719 3.969928195930951e-06 5.401217348247711 -0.37977628110467465 SSSSS(ph)QESLNRPLSAK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSSSQESLNRPLSAK 16 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 S(0.012)S(0.003)S(0.016)S(0.076)S(0.848)QES(0.045)LNRPLSAK;S(0.006)S(0.016)S(0.059)S(0.072)S(0.616)QES(0.232)LNRPLSAK 104.68 0.00057415 79604500.0 87595.0 91474.0 98623.0 93182.0 94545.0 95287.0 86113.0 85061.0 96137.0 77424.0 True False 86345.87923704444 91262.19757314594 90514.59763578932 100034.91512603972 88984.04898262172 91211.79713484609 90571.50978585504 89013.24459044726 85309.03869250974 90806.63523900503 0.9508763209844767 1.0050168397159729 0.9967839618498465 1.1016256120794 0.9799289308365383 1.0044618093686069 0.9974107018442966 0.9802504448729156 0.9394582066384742 1.0 16.470510098614795 -7.710991897572168 2.2495148808863212 0.9675782323982807 1.00896719478511 0.12819942861255262 0.03857217547499431 0.5969372922668678 6.018710617547364 0.02557903106323766 0.011409755313663787 1.945396375629058e-08 7.710991897572168 0.04138896238682932 SSSSSAS(ph)PSS(ph)PSSR ddPTM_PC-9_AZD4547_30min_R2 1 SSSSSASPSSPSSR 14 0 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 S(0.001)S(0.002)S(0.027)S(0.038)S(0.233)AS(0.699)PS(0.057)S(0.83)PS(0.101)S(0.013)R 103.11 0.015688 2229000.0 4994.4 4920.5 6821.5 7453.7 6419.0 7613.1 5865.0 7022.7 6079.9 6497.2 True False 6582.515310026509 6510.955399378102 6731.042452911082 5735.364623517036 5527.8326500052735 7137.051653498484 6386.9736379894985 5937.503080591768 6401.271101638144 6269.735005593768 1.0498873244489093 1.0384737781691125 1.0735768651953779 0.9147698616289247 0.8816692643426589 1.1383338605428952 1.0186991367723088 0.9470102125998009 1.0209795303831855 1.0 12.61418875253871 -5.717300936516003 24.99970753061899 0.9895871179325533 1.052428819945396 0.16920814505711357 0.06616054129474973 273.1308640887142 154697.35125708007 0.018992986563465198 0.03289658875269097 1.9173396943483745e-06 5.717300936516003 0.06284170201284267 SSSSSAS(ph)PSSPSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSSASPSSPSSR 14 0 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SSSS(0.001)S(0.073)AS(0.571)PS(0.013)S(0.189)PS(0.132)S(0.021)R 106.55 0.00086527 156610000.0 3413.3 4109.0 5472.0 5461.5 5516.0 4594.7 6709.1 4992.9 4018.7 4482.8 True False 3991.1042742520244 4516.9143645650365 5602.473232675561 5155.509861421904 4435.179396937318 4353.745843492926 6073.565478322336 4861.841665414838 4077.465884866544 5295.496154174725 0.7536790053384557 0.8529728344725752 1.057969464911957 0.9735650279639119 0.8375380262415689 0.8221601369799189 1.1469303916941225 0.9181088086679066 0.7699875075260054 1.0 12.370550146525296 -4.993112511810592 5.6265336069830045 0.939726232881808 0.7725635024017484 0.2306818923638836 0.10756194173354496 0.22948427717925782 26.495288773478162 0.02787895563673086 0.10150440586802321 1.0159854494366353e-05 4.993112511810592 -0.16716273048005958 SSSSSASPS(ph)SPSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSSASPSSPSSR 14 0 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SSSSSAS(0.013)PS(0.491)S(0.491)PS(0.004)SR 209.22 4.7614e-11 142340000.0 487640.0 578450.0 653890.0 598460.0 766150.0 615710.0 544310.0 519210.0 522590.0 474840.0 True False 570187.8206709808 635874.6931571295 669481.2174916345 564930.2264334988 616028.4073537928 583421.0837044924 492749.0163368603 505581.2876484676 530231.890106852 560924.7331686283 1.0165139580314564 1.1336185686894453 1.1935312848655781 1.0071408747520254 1.098237198195714 1.0401058274053698 0.8784583513608899 0.9013353445701545 0.9452817084951944 1.0 19.097447672420017 -7.081721217183984 4.017893105235143 0.9238470723769375 1.0921576058694404 0.6204445126569449 0.05838256006769461 0.14999622170746768 4.487708114470102 0.023349307916796295 0.018140374378212847 8.284738079220259e-08 7.081721217183984 0.1683105334925029 SSSSSASPS(ph)SPSSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSSSASPSSPSSR 14 0 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SSSSS(0.001)AS(0.087)PS(0.65)S(0.13)PS(0.13)S(0.001)R 113.52 0.00020087 998250.0 1880.9 0.0 1085.9 906.51 1900.4 1003.8 1241.2 1224.1 1218.0 946.51 True False 1854.078021085184 0.0 996.6214936952191 973.1777694287113 1788.622208330153 960.869813972088 1305.463262761758 1280.9761547967535 1080.8160138913934 1110.1129923547014 1.670170544668999 0.0 0.8977658135333131 0.8766474909589772 1.6112073461425227 0.8655603714122395 1.1759733214118069 1.153915109199495 0.9736090121770712 1.0 10.11649081278105 -6.019700421416191 24.254005371020106 1.13745905945474 0.789851709075902 0.08368740941984831 0.41908647618848127 1042.0785534472036 1282947.4145654705 0.11669922272637774 0.15301961529141758 9.556515721152175e-07 6.019700421416191 -0.34760735037883805 SSSSSASPS(ph)SPSSREEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSSASPSSPSSREEK 17 1 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SSSSSASPS(0.432)S(0.432)PS(0.135)S(0.002)REEK 130.64 0.00013385 7352800.0 15706.0 1606.1 8587.6 29458.0 26619.0 34481.0 22037.0 46489.0 31736.0 21999.0 True False 18364.71559235998 1765.5429936548817 8792.360952654362 27807.563764124574 21403.19803609037 32672.75565966864 19949.495825936323 45268.7130091671 32200.078961386676 25987.244556011814 0.7066819089949088 0.06793883013835901 0.3383337134379013 1.0700466416972112 0.8236039796354252 1.257261253275512 0.767664912797431 1.7419589411103904 1.239072456950331 1.0 14.665516051600436 -5.783461937893467 4.864044580391985 1.1433740739315779 0.33374894600876875 0.5844965862258689 0.2924870505321791 0.1261436007582754 7.512250685005923 0.08380373506973886 0.13407181525494952 1.6464102534401512e-06 5.783461937893467 -0.809625127922809 SSSSSASPS(ph)SPSSREEK ddPTM_PC-9_Lapatinib_30min_R1 3 SSSSSASPSSPSSREEK 17 1 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SS(0.001)S(0.069)S(0.012)S(0.001)AS(0.001)PS(0.53)S(0.357)PS(0.023)S(0.007)REEK;SSSSSAS(0.012)PS(0.601)S(0.387)PS(0.001)SREEK;SSSSSASPS(0.665)S(0.312)PS(0.013)S(0.009)REEK 210.43 4.7555e-17 14759700.0 50174.0 17333.4 36993.8 33966.7 21548.6 22306.0 15014.8 14289.6 33742.6 16042.4 True False 49458.50955921527 17293.26557726092 33952.312564197615 36464.724427589535 20281.153714177613 21352.024377825663 15792.192876019364 14953.546982749525 29942.15306266973 18815.30746484566 2.6286314827234727 0.9191061910400079 1.8045047963012983 1.93803500132644 1.0779071111152834 1.1348219750179251 0.839326856896989 0.7947543249393394 1.5913719783008256 1.0 14.199619244527062 -6.272645326169618 23.29505131511454 1.0541723763452595 1.7567459421007805 0.41041428385611844 0.4369225927333066 304.97241870606223 633978.6049462507 0.13044631868045015 0.1494771171893252 5.337706302240283e-07 6.272645326169618 0.702573565755521 SSSSSASPSS(ph)PSSR ddPTM_PC-9_AZD4547_30min_R2 8 SSSSSASPSSPSSR 14 0 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SSSSSASPS(0.001)S(0.997)PS(0.002)SR;SSSSSASPSS(0.989)PS(0.011)SR;SSSSS(0.041)AS(0.016)PS(0.103)S(0.509)PS(0.074)S(0.257)R;SSSSSASPS(0.001)S(0.947)PS(0.046)S(0.006)R;SSSSS(0.001)AS(0.005)PS(0.151)S(0.772)PS(0.055)S(0.016)R;SSSSSASPS(0.005)S(0.933)PS(0.054)S(0.008)R;SSSSSAS(0.005)PS(0.145)S(0.845)PS(0.004)S(0.001)R;SSSSS(0.001)AS(0.008)PS(0.012)S(0.974)PS(0.001)S(0.003)R 274.38 1.5104999999999999e-69 453930840.0 726947.0900000001 677723.6300000001 860119.89 974995.0000000001 923927.22 934091.71 845604.5 1048261.5 972556.07 910889.6000000001 True False 958101.1431812041 896784.5397895803 848714.1382662478 750224.9662725886 795655.8736477052 875682.8077096995 920861.6623470231 886276.7718278924 1023963.3983476306 878999.6323572141 1.0899903798729282 1.0202331227200543 0.9655454985689247 0.8534986121219523 0.9051833975333916 0.9962265915417736 1.047624627415995 1.0082788879571691 1.1649190291487006 1.0 19.745503036396464 -7.195465588992921 2.9571117994106046 1.058288800238447 0.9627825163436248 0.2469628095253954 0.07230804811402551 0.4083703134752733 7.030103437280898 0.03367836781854491 0.024136904534071798 6.375795971887594e-08 7.195465588992921 -0.09550628389482219 SSSSSASPSS(ph)PSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SSSSSASPSSPSSR 14 0 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SSSSSAS(0.001)PS(0.037)S(0.925)PS(0.037)SR;SSSSS(0.004)AS(0.014)PS(0.168)S(0.808)PS(0.005)SR;SSSSSAS(0.001)PS(0.034)S(0.584)PS(0.374)S(0.006)R;SSSSSAS(0.002)PS(0.153)S(0.84)PS(0.003)S(0.002)R;SSSSS(0.004)AS(0.079)PS(0.101)S(0.636)PS(0.101)S(0.079)R;SSSSSAS(0.027)PS(0.112)S(0.67)PS(0.15)S(0.04)R 158.31 0.00034642 143553880.0 18325.969999999998 21340.12 24855.819999999996 23908.9 32981.4 26365.600000000002 21302.499999999996 21084.4 20918.7 17253.44 True False 21428.194766593733 23458.626081660168 25448.477015022272 22569.36184669966 26518.931428960925 24982.941522013847 19284.57298325581 20530.95684076841 21224.596413207688 20381.352093844103 1.0513627686686113 1.1509847812670637 1.248615739419399 1.1073535132890626 1.3011370053790783 1.225774492633371 0.9461871270591728 1.0073402758676393 1.0413733257480142 1.0 14.314962142259219 -7.259169524453507 24.996527968431263 0.9993368686275673 1.1847170912888496 0.6193345365240686 0.06991793351308001 140.91292087051048 1551798.8622539914 0.028530546235078724 0.021010046899826225 5.505927336193192e-08 7.259169524453507 0.1853802226612823 SSSSSASPSS(ph)PSSR ddPTM_PC-9_Lapatinib_30min_R1 6 SSSSSASPSSPSSR 14 0 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SSSSSASPS(0.007)S(0.888)PS(0.105)SR;SSSSSASPS(0.023)S(0.977)PSSR;SSSSSASPS(0.004)S(0.881)PS(0.102)S(0.013)R;SSSSSAS(0.017)PS(0.116)S(0.866)PS(0.001)SR;SSSS(0.001)S(0.001)AS(0.016)PS(0.198)S(0.767)PS(0.011)S(0.007)R;SSSS(0.001)S(0.021)AS(0.106)PS(0.148)S(0.659)PS(0.056)S(0.01)R 225.33 2.0623e-20 574785690.0 270484.1 256521.17 315199.68000000005 293705.31 312094.30999999994 272051.0 241253.68000000002 293256.17 304878.3 238892.14 True False 266626.94713329116 255927.21099147867 289285.1790163505 315305.37826959183 293737.53628682136 260416.01291185565 253744.61508707757 306881.9222424826 270539.6953431729 280184.32809523196 0.9516126363879539 0.9134244328772431 1.0324816558548744 1.1253498024429924 1.048372470665036 0.9294453215218474 0.9056345756813072 1.0952858224753255 0.965577543834711 1.0 18.09601673637396 -5.261978843092838 24.970588519878707 1.0146617710624009 0.9325185319872386 0.19393520864425562 0.06535151892379543 78.55897796549354 3636542.1501666745 0.018287866592454516 0.042167996929592305 5.4704261174245235e-06 5.261978843092838 -0.0821432390751623 SSSSSASPSS(ph)PSSREEK ddPTM_PC-9_AZD4547_30min_R2 3 SSSSSASPSSPSSREEK 17 1 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SSSSSAS(0.006)PS(0.143)S(0.677)PS(0.143)S(0.03)REEK;SSSSSASPS(0.369)S(0.611)PS(0.02)SREEK;SSSSSAS(0.029)PS(0.328)S(0.628)PS(0.012)S(0.003)REEK 254.58 6.6678e-57 25579800.0 45038.0 21526.5 51778.0 131362.0 95342.0 50605.0 36079.0 39933.0 35787.4 66304.0 True False 59359.14715140434 28484.520151348992 51091.389888855825 101078.52042266872 82105.40902271448 47440.66135021095 39289.961105715796 33762.27241905124 37679.0489025749 63982.71714136696 0.9277372047244095 0.44519084877895565 0.7985186027028468 1.5797784923597453 1.2832435490556964 0.7414605610667162 0.6140714690016428 0.5276780031778738 0.5888941668314073 1.0 15.96539463994832 -6.981580918001065 23.823976160291345 0.6482243007466808 0.9975800818013735 0.2092805087996048 0.3021853741785564 234.94092999207444 303879.81310328667 0.11916630168513151 0.10507188967860338 1.0433237219336849e-07 6.981580918001065 0.34935578105469267 SSSSSASPSS(ph)PSSREEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSSSASPSSPSSREEK 17 1 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SSSSSASPS(0.008)S(0.901)PS(0.074)S(0.018)REEK;SSSSSASPS(0.181)S(0.581)PS(0.181)S(0.057)REEK 206.63 1.2018999999999999e-16 11243400.0 20160.6 4686.6 11320.7 35618.0 32155.0 40603.0 22463.7 52768.0 37272.0 22312.0 True False 23573.391389999506 5151.854675339623 11590.628421993837 33622.438935114034 25854.458576598863 38473.70720250358 20335.775712895847 51382.895912317545 37817.03248830363 26356.98897830518 0.8943886348096555 0.19546446218041785 0.4397554072483109 1.2756555372386866 0.9809336945840074 1.4597155704762728 0.7715515505065665 1.9494979473797842 1.4348009372175015 1.0 14.68589794586711 -5.763416235272715 24.858257589111062 1.2824236130169075 0.4784288611272795 0.5030995185012526 0.34437216281513205 36.87390582406301 463687.6026032553 0.09543376051531116 0.1499876439235467 1.7241846117763804e-06 5.763416235272715 -0.803994751889628 SSSSSASPSSPS(ph)SR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSSASPSSPSSR 14 0 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SSS(0.002)S(0.012)S(0.053)AS(0.033)PS(0.191)S(0.191)PS(0.417)S(0.1)R 69.27600000000001 0.030081 1075600.0 2512.9 3461.4 4256.1 2867.7 4152.4 4465.5 3431.9 3554.8 4615.1 4205.7 True False 2938.2843379626506 3805.0249164043394 4357.5815653491345 2707.032066208841 3338.7670282528125 4231.321318936526 3106.8055871956662 3461.4902666219373 4682.587106588592 4968.160117697118 0.5914230355612267 0.7658821024810439 0.8771016758954613 0.5448761718782177 0.6720328953086208 0.8516877915959485 0.6253432887818756 0.696734844412872 0.9425193624313185 1.0 12.278495955258547 -8.322765409073662 4.17053924211705 0.9916826547519684 0.706612076279638 0.5329475182330676 0.10079625487639811 0.17692870366008281 5.929300766688892 0.09489825019587066 0.025650329404683304 4.755920550249066e-09 8.322765409073662 -0.2850705784723304 SSSSSASPSSPS(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSSSASPSSPSSR 14 0 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SSSSSAS(0.019)PS(0.014)S(0.27)PS(0.601)S(0.095)R 101.72 0.0016387999999999997 881460.0 2305.6 2838.6 686.32 2375.2 2871.1 2049.3 1138.7 1901.3 2117.0 1039.4 True False 2272.721721204742 2832.0273961030657 629.8934188718137 2549.8801314349253 2702.2275427997824 1961.6562161516254 1197.6563142981086 1989.641339036897 1878.5611670017063 1219.058905086558 1.8643247768600402 2.3231259656825034 0.5167046614758035 2.091679180387 2.2166505092778217 1.609156217116793 0.9824433497847015 1.6321125507020717 1.5409929406719858 1.0 10.251552123518534 -10.602112728624268 0.09878285219178745 4.150650903000434e-11 2.293201112361637 0.16355992443865297 0.5116141843885198 117.51591659808729 2.238762944403063 43.081441486801694 13.42049305671128 2.4996964381506535e-11 10.602112728624268 2.293201112320131 SSSSSASPSSPSS(ph)REEK ddPTM_PC-9_AZD4547_30min_R2 1 SSSSSASPSSPSSREEK 17 1 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 SSSSSASPS(0.124)S(0.288)PS(0.062)S(0.526)REEK 195.25 1.9814e-11 4015600.0 9641.8 5638.2 12127.0 28984.0 21287.0 8969.3 6734.0 10228.0 7666.0 15342.0 True False 12707.69183810139 7460.637888989661 11966.188056358962 22302.186598336117 18331.667490366464 8408.448253106351 7333.31295451343 8647.497616058303 8071.209109550818 14804.881249741366 0.8583447326417013 0.5039309510922282 0.8082596445390607 1.506407665291184 1.2382178000034083 0.5679510771660693 0.4953307514466919 0.5840977357524817 0.5451721613567024 1.0 13.85378529822457 -6.786040341841797 24.99476348747699 0.6035675627968472 0.9757822946893211 0.2690514819796984 0.28086766893429393 332.14013745528655 337454.4234703853 0.10965288415553588 0.09674723162052926 1.6366644837457228e-07 6.786040341841797 0.3722147318924739 SSSSSGDPSSDPLGS(ph)PTLLAL ddPTM_PC-9_AZD4547_30min_R2 4 SSSSSGDPSSDPLGSPTLLAL 21 0 E9PPX2;P15407;P15407-2 E9PPX2 FOSL1 Fos-related antigen 1 1 SSSSSGDPSS(0.001)DPLGS(0.88)PT(0.119)LLAL;SSSSSGDPSS(0.001)DPLGS(0.864)PT(0.135)LLAL;SSSSSGDPSS(0.001)DPLGS(0.904)PT(0.095)LLAL;SSSSSGDPSSDPLGS(0.658)PT(0.342)LLAL 86.772 0.0010263 28885300.0 110120.9 79247.5 150690.0 171721.0 148761.0 131225.0 133403.5 157859.0 157654.0 157603.0 True False 145137.0555429879 104862.70460567338 148691.75214090297 132133.37651300288 128108.10295177357 123019.48000556156 145276.1530631771 133465.5187889467 165987.26858297997 152085.36694062006 0.9543130839119778 0.6894989749185784 0.9776861188687398 0.8688105842858163 0.8423433860128823 0.8088843948648463 0.9552276855136133 0.877569758838513 1.0914085419393948 1.0 17.214521823700544 -8.249145891679953 22.468710506808062 1.0457042346733934 0.8688484018588062 0.41783232471672926 0.08205454528980104 154.41433504506284 282226.78494664456 0.053894448444628686 0.019950030112145238 5.6344834595033255e-09 8.249145891679953 -0.17685583281458717 SSSSSGDPSSDPLGS(ph)PTLLAL ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSSSSGDPSSDPLGSPTLLAL 21 0 E9PPX2;P15407;P15407-2 E9PPX2 FOSL1 Fos-related antigen 1 1 SSSSSGDPSS(0.001)DPLGS(0.931)PT(0.068)LLAL;SSSSSGDPS(0.001)S(0.004)DPLGS(0.811)PT(0.182)LLAL;SSSSSGDPSS(0.001)DPLGS(0.998)PT(0.001)LLAL 124.2 3.0826e-06 13850700.0 33197.26 33434.4 42429.3 43818.8 47902.1 59997.1 53121.5 63456.7 51413.2 30671.190000000002 True False 38816.900442227685 36753.54627174818 43440.975426016295 41363.77469846635 38516.02737310206 56850.74645714182 48089.44695364508 61791.02886293127 52165.02078578159 36231.633953993565 1.07135384762158 1.014404879405034 1.1989791981553206 1.1416480623255774 1.0630496935912188 1.5690914334509485 1.3272778979470923 1.7054441690759152 1.43976451219451 1.0 15.144962248663 -6.75288662310235 24.999565091899708 1.447341012556036 1.1012965671835746 0.4238070582221536 0.17807491079137808 158.08468529893864 462078.2853857254 0.056041910125548204 0.05518717247087919 1.76649892262414e-07 6.75288662310235 -0.3460444453724614 SSSSSGDPSSDPLGS(ph)PTLLAL ddPTM_PC-9_Lapatinib_30min_R1 3 SSSSSGDPSSDPLGSPTLLAL 21 0 E9PPX2;P15407;P15407-2 E9PPX2 FOSL1 Fos-related antigen 1 1 SSSSSGDPSSDPLGS(0.92)PT(0.08)LLAL;S(0.01)S(0.01)S(0.013)S(0.013)S(0.013)GDPS(0.289)S(0.289)DPLGS(0.291)PT(0.072)LLAL;SSSSSGDPSSDPLGS(0.825)PT(0.175)LLAL 109.14 4.8085e-05 31446700.0 101389.3 69548.0 97985.5 96915.7 100739.56 94290.6 82746.0 72382.63 116108.6 109645.9 True False 99943.46998947945 69386.96587901634 89929.51042496803 104043.20387929758 94814.25714239529 90258.01084012413 87030.18300071252 75745.79123558209 103031.22679023826 128598.04772102195 0.777177194838096 0.5395646909783812 0.6993069647531456 0.8090574135698143 0.7372915749707449 0.7018614391093095 0.6767613081460931 0.5890119840691789 0.8011881098984656 1.0 16.972509215356332 -8.555593998913952 7.941593104155948 0.9999977917839944 0.6919142732244487 0.6109300773851718 0.07565469017267536 0.379447880632261 91.16374654098168 0.074811433718613 0.01933829374301106 2.7823131034433335e-09 8.555593998913952 -0.30808351855954574 SSSSSGDPSSDPLGSPT(ph)LLAL ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSSGDPSSDPLGSPTLLAL 21 0 E9PPX2;P15407;P15407-2 E9PPX2 FOSL1 Fos-related antigen 1 1 SSSSSGDPSSDPLGS(0.424)PT(0.576)LLAL 96.745 0.00075673 9646100.0 30989.0 25425.0 27977.0 40504.0 43517.0 39884.0 40413.0 50813.0 47547.0 26436.0 True False 36234.82563935078 27949.025972028747 28644.077783363336 38234.69219573974 34990.15623939833 37792.41282823076 36584.78807521734 49479.21259082377 48242.28492491339 31228.637532739136 1.1603076055227615 0.8949806389320653 0.9172375116696581 1.224347112667201 1.120450938748632 1.2101844913538211 1.1715140641938984 1.584417909329259 1.5448091475120447 1.0 14.930582007260837 -6.865378428224791 0.991898571699174 1.3908857971393211 1.013598694834347 0.3272679973636775 0.18083995397535546 0.5489540700889919 1.145077374129671 0.1102795807684455 0.09051086193913317 1.3633946069708158e-07 6.865378428224791 -0.3772871023049742 SSSSSGVPYS(ph)PAIPNK ddPTM_PC-9_AZD4547_30min_R2 2 SSSSSGVPYSPAIPNK 16 0 A0A0A0MRE1;B4DJ07;A0A0A0MSB8;Q9UPT5-4;Q9UPT5-2;Q9UPT5-5;Q9UPT5-1;Q9UPT5-6;Q9UPT5 A0A0A0MRE1 EXOC7 Exocyst complex component 7 1 SSSSS(0.001)GVPY(0.001)S(0.998)PAIPNK;SSSSSGVPY(0.001)S(0.999)PAIPNK 128.85 1.9509000000000002e-05 63385000.0 116375.0 143431.0 249560.0 367460.0 356570.0 360970.0 326290.0 395180.0 320800.0 327710.0 True False 153379.82924962637 189792.26580392246 246250.67134039264 282747.7742004065 307066.4103462187 338398.48883678834 355329.17789251346 334114.011332999 337756.8330738198 316236.97264716047 0.4850154868537747 0.6001583692608962 0.7786903260522462 0.8941009390318211 0.9710009799797388 1.0700788272924509 1.1236168083640552 1.0565305142412451 1.0680497926808514 1.0 18.270646523779092 -5.411808718413009 0.8152025997331643 1.0753605557163062 0.3822094409663374 0.9727935655462424 0.03393834047414304 0.1751941689857447 0.16190770777112565 0.014766864373106812 0.09356328651709218 3.874282470713328e-06 5.411808718413009 -0.6931511147499687 down SSSSSGVPYS(ph)PAIPNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSSSSGVPYSPAIPNK 16 0 A0A0A0MRE1;B4DJ07;A0A0A0MSB8;Q9UPT5-4;Q9UPT5-2;Q9UPT5-5;Q9UPT5-1;Q9UPT5-6;Q9UPT5 A0A0A0MRE1 EXOC7 Exocyst complex component 7 1 SSSS(0.002)S(0.012)GVPY(0.446)S(0.54)PAIPNK;SSS(0.001)S(0.003)S(0.014)GVPY(0.006)S(0.976)PAIPNK;SSSSSGVPYS(1)PAIPNK;SSSSSGVPYS(1)PAIPNK 210.02 2.3881999999999997e-17 69009900.0 270732.0 343377.0 488095.0 606236.0 710694.0 609118.0 592594.0 563787.0 532624.0 471830.0 True False 316561.58039926086 377465.19926046545 499733.03591059515 572270.5623636316 571438.6124595676 577174.7797890451 536459.2063109741 548988.1886317034 540412.6183743883 557369.0439957744 0.5679568749097247 0.6772267016381469 0.8965927356281089 1.026735461052929 1.0252428236109574 1.035534330452376 0.9624847524094668 0.984963543536633 0.969577740629753 1.0 19.088273352526258 -5.248745192251762 2.0338241653790536 1.0012930358493621 0.5683943619745491 0.9726957668584081 0.02526781526055634 0.05755664479257137 0.42821081023736174 0.007866408336466568 0.03171364249847948 5.639684483826683e-06 5.248745192251762 -0.43289867387481307 SSSSSGVPYS(ph)PAIPNK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSSSGVPYSPAIPNK 16 0 A0A0A0MRE1;B4DJ07;A0A0A0MSB8;Q9UPT5-4;Q9UPT5-2;Q9UPT5-5;Q9UPT5-1;Q9UPT5-6;Q9UPT5 A0A0A0MRE1 EXOC7 Exocyst complex component 7 1 SSSSSGVPYS(1)PAIPNK;SSSSSGVPY(0.409)S(0.591)PAIPNK 200.81 2.4007e-12 63966000.0 261432.0 222252.0 263721.0 233600.0 201015.0 216007.0 189128.0 189645.0 217271.0 135977.0 True False 257703.93173924283 221737.38914912238 242038.87737249906 250779.72326675642 189191.69291069577 206768.8841469107 198920.122429589 198456.59903310984 192799.65201493978 159480.44327203662 1.6158967610822335 1.3903735442400913 1.5176712103792998 1.572479472225848 1.1863002699834402 1.2965156097178072 1.247301037972897 1.2443945788048065 1.2089234771317279 1.0 17.283019994826255 -3.091548536528334 0.11382477773075643 0.8298103018712905 2.6361530027617603 0.7677652640535855 0.08870969698810416 35.137603414958726 0.40359454318330934 0.8919262779300122 9.768853266675613 0.0008099374184319604 3.091548536528334 1.80634270089047 SSSSSGVPYS(ph)PAIPNKR ddPTM_PC-9_AZD4547_30min_R2 1 SSSSSGVPYSPAIPNKR 17 1 A0A0A0MRE1;B4DJ07;A0A0A0MSB8;Q9UPT5-4;Q9UPT5-2;Q9UPT5-5;Q9UPT5-1;Q9UPT5-6;Q9UPT5 A0A0A0MRE1 EXOC7 Exocyst complex component 7 1 SSSSSGVPY(0.054)S(0.945)PAIPNKR 55.972 0.023125 15550000.0 34036.0 49983.0 67979.0 98751.0 95023.0 104740.0 87232.0 105120.0 81072.0 78397.0 True False 44858.74000722049 66139.02727916185 67077.55404331043 75985.48263774108 81830.69666637367 98190.59124238903 94995.47900922401 88876.1194172906 85357.30040823176 75652.34489218969 0.5929590162888881 0.8742495341474869 0.886655319658644 1.0044035349601672 1.081667683704829 1.2979186749904188 1.255684528279986 1.1747966245322043 1.1282836048224594 1.0 16.20709717992807 -5.253803825488555 0.7772401541798428 1.1850923615240003 0.5169005919620551 0.7887654116819838 0.09115601307871421 0.6788178337108856 0.48962684154757774 0.03979287768896018 0.3506823061928632 5.57437491326775e-06 5.253803825488555 -0.6681917695619453 SSSSSGVPYS(ph)PAIPNKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSSSSGVPYSPAIPNKR 17 1 A0A0A0MRE1;B4DJ07;A0A0A0MSB8;Q9UPT5-4;Q9UPT5-2;Q9UPT5-5;Q9UPT5-1;Q9UPT5-6;Q9UPT5 A0A0A0MRE1 EXOC7 Exocyst complex component 7 1 S(0.002)S(0.002)S(0.007)S(0.005)S(0.005)GVPY(0.031)S(0.947)PAIPNKR;SSSSSGVPYS(0.999)PAIPNKR 84.15899999999999 0.0015827 19273400.0 57955.0 65944.0 89339.0 105797.0 122273.0 101964.0 98153.0 93964.0 79774.0 70769.0 True False 67765.63683657342 72490.48451128684 91469.18058004405 99869.53708850201 98314.48339407468 96616.8283426366 88855.2372738182 91497.54456308733 80940.54383241922 83598.85949290406 0.8106048006830217 0.8671228884102168 1.0941438810873734 1.1946279852894288 1.1760266107747521 1.1557194551300969 1.0628761900915684 1.0944831678098876 0.9682015319753199 1.0 16.351195639856144 -5.2258478097328975 3.9694340460043733 1.105485774435311 0.8256869625821222 0.6845145710372382 0.06911969851397154 0.12059901428297139 4.2148192751547615 0.019003066353061437 0.053436601024619175 5.945004535293457e-06 5.2258478097328975 -0.2797988118531889 SSSSSGVPYS(ph)PAIPNKR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSSSGVPYSPAIPNKR 17 1 A0A0A0MRE1;B4DJ07;A0A0A0MSB8;Q9UPT5-4;Q9UPT5-2;Q9UPT5-5;Q9UPT5-1;Q9UPT5-6;Q9UPT5 A0A0A0MRE1 EXOC7 Exocyst complex component 7 1 SSSSSGVPY(0.05)S(0.949)PAIPNKR;SSSSSGVPY(0.002)S(0.997)PAIPNKR 73.722 0.004712600000000001 20197700.0 122091.0 95631.0 103038.0 105415.0 94974.0 88129.0 76491.0 81035.0 91862.0 65448.0 True False 120349.95995125295 95409.5722950511 94566.61337818194 113167.57075413161 89387.81604606817 84359.92810873296 80451.32970666252 84800.18193281187 81515.53421025549 76760.59959602167 1.5678611238660833 1.2429498049412835 1.2319681434990135 1.4742924280127279 1.1645012743061083 1.0990003797873558 1.0480810484814418 1.1047357938721323 1.061944990519332 1.0 16.22807836037441 -6.469800655352721 4.024659260003027 1.0718656240067546 1.3585528448426831 0.6987138554405181 0.09758883280288395 0.13945355450260483 4.628533346240725 0.03168800409747517 0.034966198260022716 3.389997240228154e-07 6.469800655352721 0.28668722083592857 SSSSSSQPEHSAMLVS(ph)TAASPSLIK ddPTM_PC-9_AZD4547_30min_R2 1 SSSSSSQPEHSAMLVSTAASPSLIK 25 0 P42166 P42166 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin 1 SSSSSSQPEHS(0.001)AMLVS(0.605)T(0.34)AAS(0.042)PS(0.012)LIK 89.65899999999999 4.551e-06 30360000.0 16332.0 13261.0 75844.0 115260.0 86145.0 81711.0 38450.0 86677.0 47287.0 69845.0 True False 21525.236273296658 17547.35891701108 74838.25900441072 88688.5877492486 74185.25372093864 76601.5982528818 41871.975512480196 73283.06128931203 49786.4942816762 67399.7478091635 0.31936671831834573 0.2603475456124093 1.1103640805349706 1.3158593412005428 1.1006755385938194 1.1365264818167056 0.6212482520118182 1.087289844122364 0.7386747858855839 1.0 16.04045557280896 -5.258598342025457 24.99487158707954 1.0211969525713025 0.28985705118750166 0.6991185301792819 0.18992931404763025 132.6003620471272 1166575.27615124 0.05141234932672164 0.12416480724055373 5.513173474598198e-06 5.258598342025457 -0.7313399013838009 SSSSSSQPEHSAMLVS(ph)TAASPSLIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSSSSSQPEHSAMLVSTAASPSLIK 25 0 P42166 P42166 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin 1 SSSSSSQPEHS(0.001)AMLVS(0.512)T(0.438)AAS(0.037)PS(0.012)LIK;S(0.011)S(0.011)S(0.011)S(0.01)S(0.01)S(0.01)QPEHS(0.001)AMLVS(0.41)T(0.351)AAS(0.121)PS(0.053)LIK;SSSSSSQPEHS(0.001)AMLVS(0.549)T(0.427)AAS(0.016)PS(0.006)LIK 75.82 0.00011045 37111000.0 29597.8 46104.0 119226.0 121805.0 157192.0 155889.0 140531.0 109450.0 138338.0 86843.0 True False 34608.12295680327 50680.90042927877 122068.80000712279 114980.66074713808 126391.35601221354 147713.9064130994 127218.88632366715 106577.0534718606 140360.93154021655 102586.94845119017 0.33735405409070596 0.4940287355695372 1.1899057516580862 1.1208117843747416 1.2320412871267856 1.4398898558073416 1.2401079108440056 1.0388948602225836 1.3682143163367304 1.0 16.64648767124463 -5.221451014480741 3.401246833281428 1.2184617329107454 0.36261199234043456 0.8593057363478749 0.12811387869930116 0.07886935879866426 1.8690131779210097 0.03388676520724261 0.10139246966003951 6.005497430906952e-06 5.221451014480741 -0.8558497405703109 down SSSSSSQPEHSAMLVS(ph)TAASPSLIK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSSSSQPEHSAMLVSTAASPSLIK 25 0 P42166 P42166 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin 1 S(0.001)S(0.001)S(0.001)S(0.005)S(0.005)S(0.023)QPEHS(0.003)AMLVS(0.418)T(0.333)AAS(0.161)PS(0.048)LIK 75.758 0.00011124 17048000.0 23263.0 12953.0 53180.0 24448.0 44497.0 57497.0 35938.0 33831.0 63766.0 30457.0 True False 22931.265354088286 12923.008124329956 48807.74568073645 26245.987476137183 41879.77394446794 55037.98734205337 37798.69379401552 35402.91176613752 56584.00159425169 35721.45186859851 0.6419466218349978 0.36177163716265753 1.3663427192230573 0.7347402220011422 1.1723984259800762 1.5407544896134346 1.0581511057573514 0.9910826664147712 1.584034204499754 1.0 15.124503098336127 -5.258667445353325 24.995983920911833 1.1728442338849427 0.5018590855321643 0.5318024908950771 0.2547799415568835 178.05573504820163 1605600.2658446042 0.06479989568964253 0.15638214403026054 5.512296308661868e-06 5.258667445353325 -0.6709851483527784 SSSSSSQPEHSAMLVST(ph)AASPSLIK ddPTM_PC-9_AZD4547_30min_R2 1 SSSSSSQPEHSAMLVSTAASPSLIK 25 0 P42166 P42166 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin 1 S(0.001)S(0.001)S(0.001)S(0.001)S(0.001)SQPEHSAMLVS(0.015)T(0.543)AAS(0.326)PS(0.113)LIK 62.858000000000004 0.0017054000000000001 25084000.0 10004.0 9976.9 46581.0 75177.0 54501.0 55972.0 21071.0 64250.0 34576.0 44311.0 True False 13185.063903873375 13201.737816086867 45963.30550451525 57846.10412307179 46934.476905738855 52472.06199177956 22946.27818006422 54321.638818121435 36403.61677169701 42759.68537721871 0.30835268752697714 0.3087426322159148 1.0749215084029442 1.3528187500156572 1.097633822412182 1.2271386360512224 0.5366334662576685 1.2703937912289374 0.8513537097046076 1.0 15.383963617397464 -5.260785673612079 24.31314471196817 1.0613321440018884 0.3085475560072358 0.647194824816109 0.21927764388396612 22.188525453646452 825182.8410450247 0.056395483213060406 0.13222567722099066 5.485476089816601e-06 5.260785673612079 -0.7527845879946525 SSSSSSQPEHSAMLVST(ph)AASPSLIK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSSSSQPEHSAMLVSTAASPSLIK 25 0 P42166 P42166 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin 1 SSSS(0.001)S(0.001)S(0.001)QPEHS(0.001)AMLVS(0.114)T(0.434)AAS(0.354)PS(0.094)LIK 63.724 0.0011788 18018000.0 18041.0 13266.0 49256.0 19503.0 35567.0 52881.0 35717.0 40385.0 60597.0 29309.0 True False 17783.732031685788 13235.283392060614 45206.361813658434 20937.31568010078 33475.01898741243 50619.40290163183 37566.2514953768 42261.43453269087 53771.927745301124 34375.02159821235 0.5173446067772252 0.3850261840344242 1.3150933355634418 0.6090851643621836 0.9738181223180171 1.4725635228186813 1.092835720496839 1.2294227775812845 1.5642732788303906 1.0 15.0690729995359 -5.048452857116448 0.5230438308062662 1.290522167759809 2.478914966149496e-12 0.4994152561424142 0.2707467774834692 2.7620231758767195 0.7072768946678277 0.1688061256092708 2.1104036715801837 8.944316176632354e-06 5.048452857116448 -1.2905221677573302 SSSSSSQPEHSAMLVSTAAS(ph)PSLIK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSSSSQPEHSAMLVSTAASPSLIK 25 0 P42166 P42166 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin 1 SSSSSSQPEHSAMLVS(0.001)T(0.242)AAS(0.515)PS(0.242)LIK 108.78 0.00026927 0.0 13043.0 9750.7 31875.0 15288.0 26756.0 38411.0 31066.0 26287.0 44521.0 18664.0 True False 12857.00442820674 9728.122853231227 29254.36054105821 16412.330519272964 25182.26468431992 36768.251070414306 32674.44547289457 27508.389985411537 39506.57615308595 21890.04753178323 0.5873447469467129 0.4444084846826618 1.3364228880080034 0.7497622147893054 1.1503978987599985 1.6796789050836314 1.4926621527638506 1.2566619576988474 1.8047734293735278 1.0 14.417987466722192 -5.5486450335774595 0.7157842733758106 1.462818794807069 0.3504519292827775 0.5373587841020131 0.2941297854930822 0.9641857228922529 0.7302643301057211 0.14206940174090166 0.7431799585770636 2.827189807255785e-06 5.5486450335774595 -1.1123668655242915 SSSSSSSSGSPS(ph)PSRR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSSSSSSGSPSPSRR 16 1 H3BMS0;H3BMM9;H3BTC0;Q15287-3;Q15287-2;Q15287;H3BUG0;H3BTY0;H3BUL0 H3BMS0 RNPS1 RNA-binding protein with serine-rich domain 1 1 SSSSSSSSGS(0.001)PS(0.947)PS(0.052)RR 77.03699999999999 0.0050244 642590.0 2577.4 459.95 582.44 383.91 590.13 731.34 591.81 416.44 0.0 0.0 True False 2540.645803362727 458.8850140342437 534.5540314834179 412.1440220862169 555.4197136402195 700.0622930368073 622.4510260514305 435.7893226889633 0.0 0.0 0.0 SSSST(ph)PTSPKPLLQSPK ddPTM_PC-9_AZD4547_30min_R2 1 SSSSTPTSPKPLLQSPK 17 1 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(0.005)S(0.005)S(0.03)S(0.06)T(0.429)PT(0.429)S(0.042)PKPLLQSPK 126.07 0.00016137 0.0 13512.0 15460.0 9914.1 12276.0 9746.3 14984.0 14115.0 14633.0 17237.0 12572.0 True False 17808.53493294052 20457.142663222334 9782.632556242137 9445.95786230935 8393.194478383928 14047.048111284657 15371.20765562179 12371.806082888264 18148.11262996707 12131.858106618987 1.4679148714428512 1.6862332615035431 0.8063589658129002 0.7786076773479369 0.6918309136672731 1.157864523952911 1.2670118229651446 1.019778336851662 1.4959054474982434 1.0 13.566512909060517 -5.254797867381799 24.896462490755155 1.0202559387337629 1.5770741154301564 0.47130500578825374 0.23287720693088268 447.0497849840011 1675804.811474495 0.06417985833859104 0.16161799303807795 5.561630506489452e-06 5.254797867381799 0.5568181766963936 SSSSTPT(ph)SPKPLLQSPK ddPTM_PC-9_AZD4547_30min_R2 1 SSSSTPTSPKPLLQSPK 17 1 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(0.003)S(0.003)S(0.003)S(0.001)T(0.003)PT(0.494)S(0.494)PKPLLQSPK 65.085 0.015831 17934000.0 92991.0 166880.0 103470.0 82498.0 90898.0 115520.0 123670.0 124370.0 132060.0 120550.0 True False 122560.20366704227 220820.69648373517 102097.92019390297 63479.36068139429 78278.38171369059 108296.51613825449 134676.39041946456 105151.474238284 139040.42199416642 116329.58119256451 1.0535600868721773 1.8982334004813683 0.877660859320869 0.5456854570490943 0.6729017753800178 0.9309456376275214 1.1577140486436543 0.9039100215122671 1.1952284240068556 1.0 16.82785847763902 -5.292036693898916 24.461622217220956 0.8951176127699452 1.4758967544184585 0.4213150233769808 0.2645578742991353 414.529947059883 331403.38366714725 0.0698675169852052 0.14547103681043325 5.104618688090915e-06 5.292036693898916 0.5807791416485133 SSSSTPT(ph)SPKPLLQSPK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSSTPTSPKPLLQSPK 17 1 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(0.007)S(0.007)S(0.017)S(0.021)T(0.091)PT(0.428)S(0.428)PKPLLQS(0.001)PK 54.281000000000006 0.040438 14968000.0 24324.0 49448.0 49956.0 63605.0 75458.0 78851.0 102380.0 97026.0 84031.0 88537.0 True False 23977.13529952472 49333.506194076035 45848.81051573656 68282.72388005997 71019.70879613601 75478.72654065868 107680.73545081267 101534.18217082732 74566.54389434136 103840.50248186309 0.23090349840817265 0.47508924759577975 0.44153109258831413 0.6575731265551832 0.6839307119930433 0.7268717382587964 1.036982033764911 0.9777897809052051 0.7180872791651335 1.0 16.664009744072345 -5.697124818763742 0.5067633595283783 0.9577351913897915 0.12798466182543075 0.8291820459125744 0.10299510669935302 0.7829632076507294 0.29406561838426193 0.07725276630794142 0.35167727988923186 2.0085154706016877e-06 5.697124818763742 -0.8297505295643607 down SSSSTPT(ph)SPKPLLQSPKPSLAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSTPTSPKPLLQSPKPSLAAR 23 2 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(0.004)S(0.001)S(0.041)S(0.041)T(0.035)PT(0.439)S(0.439)PKPLLQS(0.001)PKPSLAAR 61.958999999999996 0.0018045000000000001 14834000.0 97149.0 105060.0 99678.0 114710.0 145180.0 118510.0 147060.0 122970.0 106780.0 120910.0 True False 113594.40691978743 115489.66248264862 102054.70155091987 108283.1705948378 116733.02118334995 112295.12697506828 133129.412177801 119742.16779748506 108341.45549208682 142830.02587696636 0.7953118136213008 0.808581121326207 0.7145185399520244 0.7581261007969907 0.8172862846353025 0.7862151272856255 0.9320828121425849 0.8383543100428396 0.758534172537447 1.0 17.123939770542492 -7.1321233722216935 7.684586519138064 0.8686095627651748 0.7782872336077399 0.36981987338490707 0.06444913799445641 0.3439407775769213 19.868365292486214 0.02448031119409717 0.018952712990166196 7.376946397275829e-08 7.1321233722216935 -0.09032232915743488 SSSSTPTS(ph)PKPLLQSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSTPTSPKPLLQSPK 17 1 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(0.017)S(0.017)S(0.071)S(0.017)T(0.071)PT(0.355)S(0.449)PKPLLQS(0.002)PK 59.512 0.018216999999999997 12615000.0 44712.0 73249.0 57618.0 63502.0 93233.0 56543.0 115610.0 66154.0 63110.0 69316.0 True False 52280.85849774605 80520.67663422352 58991.831637481824 59944.188816261776 74964.66292869038 53577.7855417373 104658.58385608284 64417.52759595688 64032.86435761003 81882.44209484571 0.6384868008356213 0.9833692617637755 0.7204454352881985 0.7320762215033534 0.9155157199861924 0.6543256914550413 1.2781566008358076 0.7867074545888734 0.7820097046377752 1.0 16.32126651006886 SSSSTPTS(ph)PKPLLQSPK ddPTM_PC-9_Lapatinib_30min_R1 1 SSSSTPTSPKPLLQSPK 17 1 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 S(0.005)S(0.005)S(0.024)S(0.005)T(0.03)PT(0.167)S(0.763)PKPLLQS(0.001)PK 62.361999999999995 0.013721 14206000.0 20717.0 60566.0 43484.0 56138.0 69796.0 80349.0 105110.0 122930.0 91858.0 80111.0 True False 20421.571780967486 60425.763148163955 39908.9133730941 60266.5757908782 65690.7365042156 76912.6605726672 110552.08149282004 128641.7765780286 81511.98473237726 93958.07960880229 0.21734769235379656 0.6431140717195233 0.42475233145735036 0.6414198336300633 0.6991494161834858 0.8185848507429666 1.176610696526658 1.369140121995182 0.867535661347648 1.0 16.519729606233206 -6.709826056386004 1.1991215541420224 1.1351734928198427 0.46120973502234797 0.7342835885685721 0.16694310324210088 0.22848753971291222 0.6947336371346805 0.08132734524991614 0.07702278971902357 1.9506257078779915e-07 6.709826056386004 -0.6739637577974947 down SSSSVGS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 3 SSSSVGSPTR 10 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 SSSSVGS(0.997)PT(0.003)R;SSSSVGS(0.996)PT(0.004)R;SSSSVGS(0.991)PT(0.009)R 126.71 0.00033715 151209000.0 77585.0 64321.6 96405.0 135746.0 101454.0 104499.0 84972.0 110121.0 70616.0 93877.0 True False 102255.41613174875 85112.29932255643 95126.60671009195 104451.8569547935 87368.86332351406 97964.66101048698 92534.34338742417 93104.3297788379 74348.61759457871 90590.39480393505 1.1287666463211725 0.939528958967064 1.0500738727982655 1.1530124930005972 0.9644384872436713 1.081402296816479 1.0214586611273349 1.0277505687037103 0.8207119281850085 1.0 16.4670704706229 -8.115538618398556 7.209615365213157 0.9112624902650419 1.0448138069353732 0.35280570837467173 0.07369760006267227 0.26875372973668393 14.969563695696902 0.047440724382881494 0.01773489861751004 7.66410386274007e-09 8.115538618398556 0.13355131667033127 SSSSVGS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSSSVGSPTR 10 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 SSSSVGS(0.997)PT(0.003)R;S(0.004)S(0.014)S(0.048)S(0.013)VGS(0.917)PT(0.004)R;SSSSVGS(0.999)PT(0.001)R;SSSSVGS(0.5)PT(0.5)R 126.71 0.00033715 154585900.0 62619.9 76294.0 78493.7 86322.0 103635.0 99717.0 97607.0 101229.0 105872.0 83350.0 True False 73220.21227059874 83867.9641105196 80365.287497015 81485.65819969992 83328.46570007241 94487.664978254 88360.95834651557 98571.84601099146 107420.17770985386 98460.69520176313 0.7436491497501391 0.8517913055423744 0.8162169415149113 0.8275958039166958 0.8463119778843513 0.9596485662083972 0.8974236690635646 1.0011288850744002 1.090995523540954 1.0 16.58726030559994 -7.133236051531629 0.7347190299938439 1.0450989550511176 0.7995652459059406 0.8125153536450023 0.04374409374197645 0.28515794737251726 0.3124965176155777 0.035051317666746 0.02462296305231059 7.358070565069316e-08 7.133236051531629 -0.24553370914517703 SSSSVGS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 4 SSSSVGSPTR 10 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 S(0.003)S(0.001)SS(0.001)VGS(0.857)PT(0.138)R;SS(0.001)SSVGS(0.963)PT(0.036)R;SSSSVGS(1)PTR;SSSSVGS(0.583)PT(0.416)R 134.75 0.00011211 210780000.0 65464.0 64736.0 64189.0 60118.6 71363.0 69211.0 74520.0 69788.0 87510.0 65111.0 True False 64530.47135537273 64586.10776936802 58911.6281967054 64539.922393770496 67165.56864505624 66251.00686872107 78378.28097083954 73030.60525361981 77653.70227884708 76365.34959504611 0.8450229285607681 0.8457514843035274 0.7714444903232271 0.8451466893822386 0.8795293808150566 0.8675532452878189 1.0263592242616277 0.9563317085679574 1.0168709066432997 1.0 16.220630550440987 -7.04884524430792 1.6600754898490477 0.9999700556021938 0.8288527906663107 0.8430868448860847 0.033018584325828125 0.14044351045127768 0.7754423408802517 0.016129750658608312 0.011697319784330874 8.936238592777394e-08 7.04884524430792 -0.17111726493588308 SSSSVS(ph)PSSNAPGSCSPDGVDQQLLDDFHR ddPTM_PC-9_AZD4547_30min_R2 1 SSSSVSPSSNAPGSCSPDGVDQQLLDDFHR 30 0 J3KN34;P26045-2;P26045;P26045-3 J3KN34 PTPN3 Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 3 1 S(0.009)S(0.009)S(0.003)S(0.011)VS(0.592)PS(0.159)S(0.184)NAPGS(0.025)CS(0.008)PDGVDQQLLDDFHR 103.46 8.1812e-14 6243400.0 11717.0 11868.0 15497.0 20204.0 21720.0 14768.0 14917.0 18598.0 15146.0 15754.0 True False 15442.76227125993 15704.09890861077 15291.499654440073 15546.279948688332 18704.55291449051 13844.554625430586 16244.584101941911 15724.106439524083 15946.58663882816 15202.4572551444 1.0158069851526281 1.0329974059487401 1.005857105716613 1.022616257870259 1.2303637892592019 0.9106787404875413 1.0685498948826093 1.0343134781190166 1.048947967502553 1.0 13.892016912645364 -6.035426935614649 24.99745643646469 1.052049235871685 1.0187877189527363 0.035435598018438874 0.07447500743618533 2264.4888027337242 1597830.1085255903 0.02161295088170706 0.02790962483363301 9.216649338032201e-07 6.035426935614649 -0.03326151691894874 SSSSVSPS(ph)SNAPGSCSPDGVDQQLLDDFHR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSSVSPSSNAPGSCSPDGVDQQLLDDFHR 30 0 J3KN34;P26045-2;P26045;P26045-3 J3KN34 PTPN3 Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 3 1 S(0.002)S(0.002)S(0.002)S(0.004)VS(0.125)PS(0.426)S(0.426)NAPGS(0.009)CS(0.004)PDGVDQQLLDDFHR 92.208 1.3373e-09 4775400.0 14474.0 10897.0 16438.0 13265.0 12310.0 14261.0 10099.0 10856.0 14577.0 8984.5 True False 14267.598105793484 10871.768666009686 15086.531092514977 14240.552350742795 11585.950002391175 13651.090274014705 10621.876805213496 11360.409391776455 12935.184757384926 10537.458853906272 1.3539884998463778 1.031725847449405 1.4317048637321463 1.3514218701279934 1.0995013278838308 1.2954821900874327 1.0080112247627835 1.0780976276424665 1.227543085740241 1.0 13.363239377371016 -7.253898412334334 24.95193614673524 1.0849211188825185 1.2548103536615742 0.33210991162774883 0.12630038453532166 738.284295131993 2442877.540675617 0.04861438386848063 0.03690107465800839 5.573160978601311e-08 7.253898412334334 0.1698892347790557 SSSSVSPSSNAPGS(ph)CSPDGVDQQLLDDFHR ddPTM_PC-9_AZD4547_30min_R2 1 SSSSVSPSSNAPGSCSPDGVDQQLLDDFHR 30 0 J3KN34;P26045-2;P26045;P26045-3 J3KN34 PTPN3 Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 3 1 SSSSVS(0.003)PS(0.011)S(0.043)NAPGS(0.681)CS(0.262)PDGVDQQLLDDFHR 77.766 9.7511e-07 5192700.0 7231.4 4365.1 11879.0 20156.0 15157.0 6150.4 13134.0 10400.0 10390.0 12028.0 True False 9530.834777535976 5776.033210817063 11721.47669839929 15509.345607095733 13052.712178864313 5765.814515726455 14302.9005560706 8792.918968225096 10939.194188394596 11606.903381038273 0.8211350146246684 0.4976377437804069 1.009871135616429 1.3362173439328116 1.124564558725284 0.4967573457314922 1.232275318103937 0.7575594178366067 0.9424730980586531 1.0 13.502695504835769 -5.277724897721838 24.173537524342265 0.9873760465347107 0.6593863847798888 0.23878096003893012 0.23431089014608258 665.3446706098565 987609.9377866869 0.06231954442338865 0.13042710037928185 5.275639390819898e-06 5.277724897721838 -0.3279896617548219 SSSSVSPSSNAPGSCS(ph)PDGVDQQLLDDFHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSSVSPSSNAPGSCSPDGVDQQLLDDFHR 30 0 J3KN34;P26045-2;P26045;P26045-3 J3KN34 PTPN3 Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 3 1 SSSSVSPSSNAPGS(0.049)CS(0.951)PDGVDQQLLDDFHR 143.37 1.3862e-14 2636700.0 4759.7 5216.1 6044.2 5178.5 9221.3 7565.3 6766.6 7652.5 4847.0 6429.0 True False 5565.423201639866 5733.919935996029 6188.31665075615 4888.365433923523 7414.452460655921 7168.562350050499 6125.618662058393 7451.629983493969 4917.878205376894 7594.526808064004 0.7328202720583461 0.7550068728321099 0.8148390027651604 0.6436695211521235 0.9762889312317816 0.9439116525915467 0.8065833220252908 0.9811842359397158 0.6475555791250882 1.0 12.890744362236502 -6.2646412081487695 24.976924153953384 0.8899125169228282 0.7434894927317829 0.34224002034931145 0.10573953377047056 337.4459793288215 2632355.5601509074 0.030956234219234047 0.03656201006606786 5.436993225257399e-07 6.2646412081487695 -0.14642302419104536 SSST(ph)GNLLDKDDLAIPPPDYGAASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSTGNLLDKDDLAIPPPDYGAASR 25 1 I3L4C2;Q9UQB8-5;B4DWA1;Q9UQB8-3;Q9UQB8-4;Q9UQB8-2;Q9UQB8;Q9UQB8-6;I3L3C6 I3L4C2 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 S(0.046)S(0.046)S(0.142)T(0.767)GNLLDKDDLAIPPPDYGAASR 86.825 6.4766e-06 15709000.0 12037.0 18301.0 31853.0 34519.0 34086.0 40259.0 39464.0 33304.0 38433.0 31701.0 True False 14074.626358413161 20117.802332904546 32612.496323175208 32585.012342107944 27407.092988398348 38147.747168080976 35725.68422538234 32429.805288504816 38995.00991690744 37448.140355022086 0.37584313199482133 0.537217660000748 0.8708709167931117 0.8701369956742869 0.7318679306520716 1.018682017489423 0.9540042278919533 0.8659924092640752 1.041306979391245 1.0 15.192606456919679 -4.752215714508986 0.8419244400384183 0.9432566656486299 1.3081557425397348e-19 0.8331354057891365 0.0847654167842566 0.9913653302236947 0.5237649874981682 0.03158989674510499 0.8846246126164882 1.7692299617224974e-05 4.752215714508986 -0.9432566656486299 down SSST(ph)SDILEPFTVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSTSDILEPFTVER 15 0 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 SSS(0.198)T(0.801)S(0.001)DILEPFTVER 256.13 1.4088e-49 14080000.0 71022.0 58371.0 78453.0 116740.0 110650.0 105580.0 108890.0 114090.0 104570.0 89959.0 True False 83044.62185155907 64165.68711950008 80323.61705465942 110199.4362761866 88968.92680767123 100043.19893703237 98575.15090466972 111095.25838834749 106099.1384229962 106267.85458494787 0.7814651210933714 0.6038108830757247 0.7558599669521956 1.0369969047233933 0.8372139171827516 0.9414248488197373 0.9276102476113434 1.045426755082749 0.9984123499753464 1.0 16.697345730342356 -5.636046294747205 5.114090939302159 0.962377148122293 0.6899688141653302 0.7396657623804088 0.06997072111332583 0.09962357372709744 4.033440786906361 0.01918881790826722 0.033907370622620045 2.3118183427655296e-06 5.636046294747205 -0.27240833395696284 SSST(ph)SESGDSDNMR ddPTM_PC-9_AZD4547_30min_R2 1 SSSTSESGDSDNMR 14 0 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 S(0.006)S(0.006)S(0.049)T(0.47)S(0.47)ESGDSDNMR 143.76 0.00064544 864890.0 3693.9 6517.6 7720.1 7918.7 7132.0 7203.0 6556.5 7110.9 6413.1 8516.9 True False 4868.483362106941 8624.28674138537 7617.726429776274 6093.166057695425 6141.844907281136 6752.595271328314 7140.015798376494 6012.073797226137 6752.083373396863 8218.725923342601 0.5923647299491528 1.0493459475137021 0.9268743721141273 0.7413759887514658 0.7472989079532676 0.8216109570158286 0.868749714368454 0.7315092209305591 0.8215486726744081 1.0 13.004699047603046 -10.786609277872838 17.371279241732694 0.9999999998196629 0.8173175728434142 0.1879585027177888 0.11711449605640886 0.0 0.0 0.11204740600711129 0.02717548785210767 1.6345218183851007e-11 10.786609277872838 -0.1826824269762487 SSST(ph)SESGDSDNMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSTSESGDSDNMR 14 0 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 SSS(0.068)T(0.749)S(0.182)ESGDSDNMR 181.76 0.00010372 1402800.0 5061.0 7445.9 7331.8 6656.6 9616.4 7123.1 7731.6 9160.9 7028.2 6770.6 True False 5917.727340693612 8185.079743761209 7506.617918006342 6283.652282988382 7732.135451905002 6749.552096499105 6999.20687606341 8920.436081775875 7130.974128951909 7998.056183959893 0.7398956952267499 1.0233836266587364 0.9385552871034926 0.7856474296329964 0.9667518299523582 0.8438990601285518 0.8751134919632503 1.1153255086736968 0.8915884015985136 1.0 12.965433700348216 -7.714880735907617 24.999293337192015 1.0025934137600436 0.887614372246619 0.2586495819454875 0.09306652521580452 161.4024838565875 86663.53471051816 0.04167286256024194 0.024059722194186745 1.9280543145228394e-08 7.714880735907617 -0.11497904151342464 SSSTGSSSSTGGGGQESQPS(ph)PLALLAATCSR ddPTM_PC-9_AZD4547_30min_R2 1 SSSTGSSSSTGGGGQESQPSPLALLAATCSR 31 0 P08047;H3BVI2;P08047-2 P08047 SP1 Transcription factor Sp1 1 SSSTGSSSSTGGGGQES(0.062)QPS(0.937)PLALLAATCSR 91.064 1.4407e-09 6424900.0 8450.2 7963.7 9661.6 17232.0 9289.3 13138.0 9095.9 12706.0 8224.6 11204.0 True False 11137.187824921111 10537.810286358585 9533.480871222702 13259.42863174606 7999.641039989723 12316.478783105842 9905.417478906857 10742.579654833478 8659.335565146315 10811.751370232181 1.030100253284121 0.9746626541350336 0.8817702650350506 1.2263904503254697 0.7399024233959915 1.1391751772073304 0.9161714082862913 0.9936021729477472 0.800918858436564 1.0 13.40031262033627 -8.144170972340348 18.412648572105788 0.8992051486259179 0.9861237358301176 0.06342985830192305 0.13397935445735087 7.401884029810046 1125.2697602084745 0.08294445506875138 0.03134974532454822 7.1751176680591155e-09 8.144170972340348 0.08691858720419965 SSSTGSSSSTGGGGQESQPS(ph)PLALLAATCSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSSTGSSSSTGGGGQESQPSPLALLAATCSR 31 0 P08047;H3BVI2;P08047-2 P08047 SP1 Transcription factor Sp1 1 SSSTGSSSSTGGGGQESQPS(1)PLALLAATCSR;SSSTGSSSS(0.001)TGGGGQES(0.035)QPS(0.963)PLALLAATCSR;SSSTGSSSSTGGGGQES(0.009)QPS(0.991)PLALLAATCSR 99.774 6.254e-13 11337100.0 11569.9 11396.8 12423.7 15844.28 15877.8 16227.7 20942.800000000003 16383.0 18371.3 13512.660000000002 True False 13528.455554058672 12528.198985172754 12719.92812514463 14956.576359448827 12766.659069740997 15376.690844766832 18958.94637125831 15952.963609223349 18639.945507415014 15962.398291842304 0.8475202351624369 0.7848569341597859 0.7968682332431987 0.9369880444026065 0.799795797368713 0.96330705221315 1.187725429764988 0.9994089432899456 1.1677409100198364 1.0 13.96238980703753 -6.9847193529593135 4.300339869164339 1.0886808945660218 0.8357182401956594 0.7503385272414447 0.06941016819834889 0.0975582896884189 4.328443256186287 0.02484312167291525 0.020792667177709577 1.035811305901084e-07 6.9847193529593135 -0.25296265437036236 SSSTGSSSSTGGGGQESQPS(ph)PLALLAATCSR ddPTM_PC-9_Lapatinib_30min_R1 3 SSSTGSSSSTGGGGQESQPSPLALLAATCSR 31 0 P08047;H3BVI2;P08047-2 P08047 SP1 Transcription factor Sp1 1 SSSTGSSSSTGGGGQES(0.001)QPS(0.999)PLALLAATCSR;SSSTGSSSSTGGGGQES(0.002)QPS(0.998)PLALLAATCSR;SSSTGSSSSTGGGGQES(0.001)QPS(0.999)PLALLAATCSR 146.45 1.2008000000000002e-16 17186000.0 16930.8 21273.5 17860.7 9922.7 19198.5 24788.5 22145.2 19058.7 23951.5 24222.3 True False 16689.363687271547 21224.242517789946 16392.262190295787 10652.448459156845 18069.281975703256 23728.353639815814 23291.77009870422 19944.23677920504 21253.829849523558 28409.09228081403 0.5874655734263866 0.7470933005530647 0.5770076012377994 0.3749661676572093 0.6360386948338463 0.8352380077923385 0.8198702678872364 0.7020371007303989 0.7481347745798006 1.0 14.794065115234268 -6.654119516901644 4.965060452976046 0.8016993690906346 0.5760499152016659 0.5310350653382949 0.11140509508447868 0.1949925764112218 7.737958063990993 0.03912294597175032 0.038871654258106875 2.217586060934048e-07 6.654119516901644 -0.22564945388896862 SSSTS(ph)ESGDSDNMR ddPTM_PC-9_Lapatinib_30min_R1 1 SSSTSESGDSDNMR 14 0 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 SS(0.003)S(0.023)T(0.312)S(0.628)ES(0.033)GDSDNMR 109.0 0.00055659 871210.0 3594.6 4542.8 4731.7 3241.2 5369.1 3641.6 3562.1 4494.0 5806.4 3460.3 True False 3543.3403448310924 4532.281425708798 4342.6778908902 3479.5686603262398 5053.300094056738 3485.857256984218 3746.52810851084 4702.807646153593 5152.422087897359 4058.408244440076 0.8730862277557674 1.1167633103244154 1.0700446158514403 0.857372755708637 1.2451433640220007 0.8589222786445303 0.9231521036957028 1.1587813159497518 1.2695672237892914 1.0 11.986698281004848 -7.780392976078068 24.17072455821454 1.1606309101217545 0.9992961784265338 0.20624889538370472 0.13360071519423145 251.31817639624072 320488.8741038036 0.07033516095498576 0.0338881702168873 1.6580858914102173e-08 7.780392976078068 -0.1613347316952206 SSSTSES(ph)GDSDNMR ddPTM_PC-9_AZD4547_30min_R2 1 SSSTSESGDSDNMR 14 0 O75179-4;O75179-6;O75179-2;O75179;H0YM23;O75179-7 O75179-4 ANKRD17 Ankyrin repeat domain-containing protein 17 1 SS(0.001)S(0.041)T(0.293)S(0.293)ES(0.311)GDS(0.061)DNMR 115.37 0.00014087 1160800.0 4256.6 5163.4 6687.9 10430.0 7734.5 5985.3 6752.7 7642.5 6519.7 6752.5 True False 5610.110257219853 6832.368074209718 6599.214076203764 8025.5246418936495 6660.698182188159 5611.038244825956 7353.677218286736 6461.527232178875 6864.318031768652 6516.097030301036 0.8609617430697886 1.0485368837262496 1.0127556488978324 1.231645969139732 1.0221913748697573 0.8611041577087646 1.128540165085142 0.9916253858915235 1.0534401191155265 1.0 12.669792371658094 -4.759881316801838 24.825414916910844 1.0405431914647416 0.8609615056554539 0.25803766398506933 0.0904643452452472 52.91944219617703 842893.8825108092 0.02274512043170578 0.1397389247446805 1.7382757966635248e-05 4.759881316801838 -0.17958168580928768 SSSVGS(ph)SSSYPISPAVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 SSS(0.464)VGS(0.497)S(0.039)SSYPISPAVSR 279.19 6.866999999999999e-92 79896000.0 23653.0 25278.0 24081.0 25039.0 31073.0 35120.0 37436.0 34496.0 32921.0 25401.0 True False 27656.985731955327 27787.43278351791 24655.18236770106 23636.146007533265 24984.468709396886 33278.245374773425 33889.79106683089 33590.51655153323 33402.407344586914 30006.00022579463 0.9217151744263478 0.9260625399726042 0.8216750710581632 0.7877139848587509 0.8326490875621274 1.1090530268731322 1.1294338069656336 1.1194599846285802 1.1131909315881618 1.0 14.872963401284984 -6.763967684298793 24.99968845769724 1.1038942291024516 0.8558277126119137 0.8353033829243381 0.05236301137827146 26.19036544223034 258965.94120959134 0.019213764797276177 0.017727263504262333 1.7219967033941726e-07 6.763967684298793 -0.2480665164905379 SSSVGSSSSYPIS(ph)PAVSR ddPTM_PC-9_AZD4547_30min_R2 4 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 SSSVGSSSSYPIS(1)PAVSR;SSSVGSSS(0.001)S(0.004)YPIS(0.995)PAVSR;SSSVGSSSS(0.002)YPIS(0.998)PAVSR;SSSVGSSSSYPIS(0.991)PAVS(0.009)R 289.58 3.947899999999999e-106 424580000.0 57144.0 71931.8 91644.0 129276.0 96078.7 93343.0 84042.9 134153.0 93209.0 87787.0 True False 75314.6033309616 95182.34764698434 90428.74068087408 99473.41549428983 82739.83094408206 87506.24745406078 91522.55528732973 113422.7363792598 98135.83745005514 84713.60385028335 0.8890496910515947 1.123578071536216 1.067464215554933 1.174231893971739 0.9767006381915991 1.0329657041708784 1.0803761276533579 1.3388963663937008 1.1584424813692646 1.0 16.370306044873224 -7.546532554635282 24.98239096246567 1.1911289849618916 1.0519702757927338 0.19592476589063068 0.10598082199429942 309.35709115449276 326728.8324636253 0.04771236424945078 0.02754861547065694 2.840975218016339e-08 7.546532554635282 -0.13915870916915773 SSSVGSSSSYPIS(ph)PAVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 SSSVGSSSSYPIS(1)PAVSR;SSSVGSSSS(0.003)YPIS(0.996)PAVSR;SSSVGSSSSYPIS(1)PAVSR;SSSVGSSSSYPIS(1)PAVSR;SSSVGSSSSYPIS(1)PAVSR;SSSVGSSSSYPIS(1)PAVSR 308.42 4.362899999999999e-138 337824000.0 84287.2 80956.2 108681.0 115015.0 112702.0 103876.0 109241.0 84282.0 88930.3 63703.5 True False 98555.35821191678 88992.9965151133 111272.36721498755 108571.08243366094 90618.85213807647 98428.55969675304 98892.9016436498 82069.6868041605 90230.73739790157 75252.44027337141 1.3096632860528148 1.1825928327616517 1.478654603236329 1.4427582951363713 1.2041981869143794 1.3079783105928415 1.3141487675934376 1.090591700495345 1.1990406832006792 1.0 16.199450745650473 -8.126530860879072 0.716917948306361 1.0111862100951203 1.337622147890578 0.5369350259636686 0.09564113253832288 0.5225018918091505 0.5767705357261698 0.09490848646285395 0.0407388839581176 7.47255532475833e-09 8.126530860879072 0.32643593779545776 SSSVGSSSSYPIS(ph)PAVSR ddPTM_PC-9_Lapatinib_30min_R1 4 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 SSSVGSSSSYPIS(1)PAVSR;SSSVGSSSSYPIS(1)PAVSR;SSSVGSSSSYPIS(1)PAVSR;SSSVGSSSSYPIS(1)PAVSR 274.16 1.7709999999999998e-91 401231000.0 105237.0 100741.0 116482.0 91383.0 80974.0 83240.0 70949.0 67604.3 79489.0 51137.4 True False 103736.30108189801 100507.74040400864 106905.29959352268 98103.61066475173 76211.26852100927 79680.01924191733 74622.39206387674 70745.44257963076 70536.11176372172 59976.43145369766 1.729617760969713 1.6757872712317257 1.7824551578407015 1.6357026966582464 1.2706869460855645 1.3285221763057211 1.2441952656267303 1.1795540492309362 1.176063831309741 1.0 15.872108065190398 -6.293150686518195 1.7584385740579298 1.1911200341744577 1.7355584356249947 0.9053275949898134 0.08090127598643812 0.10368245970922682 0.6331379893496535 0.028808301304420664 0.03735480366725162 5.091541799282242e-07 6.293150686518195 0.544438401450537 SSSVLS(ph)LEGSEK ddPTM_PC-9_AZD4547_30min_R2 2 SSSVLSLEGSEK 12 0 A1L390-3;A1L390;G3V311;A1L390-2;A0A0U1RR71 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 S(0.001)S(0.002)SVLS(0.996)LEGS(0.001)EK;S(0.048)S(0.211)S(0.13)VLS(0.611)LEGSEK 160.48 0.00057931 32100000.0 122045.0 111984.0 135123.0 143076.0 146022.0 140567.0 103629.0 136179.0 100372.0 121167.0 True False 160852.77130629987 148180.63803352448 133331.1807322004 110092.03870216449 125749.36582319222 131777.32326875016 112851.78024402636 115135.66463210835 105677.45900650065 116924.98021036419 1.3756920977613467 1.2673137747547791 1.1403139046277295 0.9415613199514228 1.075470490539761 1.1270245505422756 0.9651639884051332 0.9846968921864548 0.9038056608294678 1.0 16.835223659016528 -5.278637941113572 1.7227726846458042 1.0047725430335108 1.3764202998073123 0.8056041399419868 0.0634707482850681 0.19910363439371304 1.0194072444121884 0.019675014513378022 0.08726259707846949 5.2645597478271134e-06 5.278637941113572 0.37164775677380146 SSSVLS(ph)LEGSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSSVLSLEGSEK 12 0 A1L390-3;A1L390;G3V311;A1L390-2;A0A0U1RR71 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 SSS(0.005)VLS(0.986)LEGS(0.008)EK;S(0.001)S(0.001)S(0.007)VLS(0.992)LEGSEK;S(0.002)S(0.01)S(0.474)VLS(0.514)LEGSEK;SS(0.001)S(0.141)VLS(0.857)LEGSEK 160.84 9.091299999999999e-05 40385000.0 88139.0 95850.0 96295.0 112412.0 116970.0 99625.0 117310.0 98431.0 93968.0 78994.7 True False 103059.19187539877 105365.35454941791 98591.03800082118 106113.92008462129 94050.56817617067 94400.48962021084 106197.54754914847 95847.2905462652 95342.10423000954 93315.813788299 1.104412935938212 1.1291264606924516 1.0565308707963457 1.1371483114893766 1.0078738464365598 1.0116237086499893 1.1380444882586958 1.0271280574556123 1.021714330716844 1.0 16.509833968029668 -1.5228787453161634 0.12417432254867468 0.9790511159729478 1.4381459095680156 0.3520840547275319 0.04401195429530474 106.13999030088976 0.9035785055877187 0.27888782038681453 8.465946605227673 0.02999999999752524 1.5228787453161634 0.4590947935950678 SSSVLS(ph)LEGSEK ddPTM_PC-9_Lapatinib_30min_R1 2 SSSVLSLEGSEK 12 0 A1L390-3;A1L390;G3V311;A1L390-2;A0A0U1RR71 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 SSS(0.001)VLS(0.996)LEGS(0.002)EK;SSSVLS(0.997)LEGS(0.003)EK 92.15100000000001 0.0060168 28844000.0 52726.0 44012.0 56923.0 45471.0 53167.0 48236.0 45987.0 51406.0 54090.0 44865.0 True False 51974.1175712358 43910.092918089205 52243.01066913431 48815.08902680935 50039.82159034379 46173.05872360797 48367.98184388089 53794.51042682946 47997.814607048815 52619.855471145296 0.987728246417104 0.8344776420408035 0.9928383535333419 0.9276933315329546 0.9509684346773567 0.8774835717465529 0.9191964023999273 1.0223234166108324 0.9121616579385887 1.0 15.683319665465865 -8.382272298776181 0.743776591985784 0.9942731307605852 0.9270221495891207 0.1070634397404231 0.05337769619090132 1.3904237730138371 1.746961460288779 0.04963934891413523 0.019560303403120437 4.146939516874046e-09 8.382272298776181 -0.06725098117146455 SSSVLSLEGS(ph)EK ddPTM_PC-9_AZD4547_30min_R2 1 SSSVLSLEGSEK 12 0 A1L390-3;A1L390;G3V311;A1L390-2;A0A0U1RR71 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 SSSVLS(0.015)LEGS(0.985)EK 107.65 0.0015267999999999998 14974000.0 11291.0 7749.7 14804.0 15693.0 17914.0 15212.0 10148.0 15835.0 10814.0 12854.0 True False 14881.303132610374 10254.638971356666 14607.689287238232 12075.221304433082 15426.950318148398 14260.791235241753 11051.15234071908 13388.064602100423 11385.605962781441 12403.9853724531 1.199719500287297 0.8267213047614741 1.1776609572338854 0.9734952873493272 1.2437091672494818 1.1496942963922117 0.8909356153596887 1.0793357296141912 0.9178990155911271 1.0 13.598516109298384 -7.25298103882202 24.866470030090642 0.97865389931471 1.0879358272040374 0.19110255354251993 0.1232612855886152 1128.644776210808 3318083.245663786 0.046535633748752823 0.03543749799998618 5.584945779246567e-08 7.25298103882202 0.10928192788932733 SSSVS(ph)SQEEK ddPTM_PC-9_AZD4547_30min_R2 1 SSSVSSQEEK 10 0 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4;A0A2R8Y670 P49815 TSC2 Tuberin 1 S(0.005)S(0.13)S(0.237)VS(0.602)S(0.026)QEEK 124.6 0.00040737 5169900.0 47919.0 39552.0 38457.0 59730.0 51645.0 42517.0 55133.0 56350.0 85951.0 65817.0 True False 63156.245222881626 52336.41051848446 37947.03505264259 45960.17131930086 44474.98320759036 39858.40526878605 60039.730193226795 47642.40229418122 90494.19438755572 63512.7668631357 0.994386614568023 0.8240297676097896 0.5974709798805496 0.7236367361910228 0.7002526484703453 0.6275652477033056 0.9453175032132832 0.7501232373775546 1.42481895935289 1.0 15.954759000391979 -8.244805224749516 24.872831697197984 1.2124094615176138 0.7635540129341635 0.5736888866873289 0.15233907441024064 447.5984744498429 669290.8915654327 0.10181048981647031 0.03824343138315047 5.691081109721658e-09 8.244805224749516 -0.4488554485834503 SSSVSS(ph)QEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSSVSSQEEK 10 0 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4;A0A2R8Y670 P49815 TSC2 Tuberin 1 SSSVS(0.324)S(0.676)QEEK 120.03 0.00073983 2363900.0 29306.0 35100.0 33084.0 37220.0 34322.0 35410.0 29329.0 21541.0 24872.0 21718.0 True False 34266.926980115975 38584.49603218129 33872.848031768706 35134.684068868126 27596.85048253853 33553.037264257604 26550.744796428113 20975.571574576108 25235.705946798862 25655.301480406597 1.3356665095627984 1.5039580050013814 1.3203059826694297 1.3694902044203652 1.0756782766172024 1.3078403031000296 1.0349028568892624 0.8175920906872024 0.9836448800288632 1.0 14.646969358566674 -6.84932164910565 0.776979895003473 0.9136304584706552 1.4134718672465125 0.7448952833981266 0.10535322015593632 0.31529079780911407 0.41092820286984344 0.07512964392504735 0.06661959172690247 1.414745596690512e-07 6.84932164910565 0.49984140877585737 SSSYADPWT(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSSYADPWTPPR 12 0 O94929;A0A0C4DGA7;O94929-2;O94929-3;A0A0A0MRD5;O94929-4 O94929 ABLIM3 Actin-binding LIM protein 3 1 SSSY(0.001)ADPWT(0.998)PPR;SSSYADPWT(1)PPR;SSSYADPWT(1)PPR;SSS(0.004)Y(0.015)ADPWT(0.981)PPR 120.03 0.0011683 6425800.0 35093.1 36356.5 41296.5 42981.0 52070.8 43072.0 38442.700000000004 35959.9 34966.3 29238.1 True False 41033.66870968087 39965.733048262075 42281.165177848394 40572.9139162821 41867.90053336543 40813.228496077485 34801.12915495406 35015.990727663506 35477.61598775949 34538.73608132776 1.1880477795440922 1.1571278391356146 1.2241665438564302 1.1747075463544978 1.212201292912972 1.1816653742040613 1.0075970664649814 1.0138179534193712 1.0271833892306008 1.0 15.075927669058904 -7.250538622970344 7.032815636217349 1.0130046498493936 1.1903998383751446 0.956557069347986 0.018532907865944734 0.0270193993037363 8.179336244911362 0.007132848297547452 0.005258810310510802 5.6164432760166514e-08 7.250538622970344 0.17739518852575098 SSSYADPWT(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 2 SSSYADPWTPPR 12 0 O94929;A0A0C4DGA7;O94929-2;O94929-3;A0A0A0MRD5;O94929-4 O94929 ABLIM3 Actin-binding LIM protein 3 1 SSSY(0.002)ADPWT(0.998)PPR;SSSYADPWT(1)PPR 121.21 0.0011183 5837800.0 23540.6 23875.5 29459.7 22857.1 22021.9 19160.3 15012.800000000001 15934.4 22565.3 16489.6 True False 23204.90672718267 23820.217746656337 27037.637183730592 24538.087383050388 20726.615138721223 18340.858633840813 15790.089325805442 16674.770395387124 20023.75829085669 19339.805388989116 1.1998521319347972 1.2316679132778703 1.3980304682447395 1.268786675434741 1.0717075338576918 0.9483476314752867 0.8164554403838695 0.8621994927043425 1.0353650353822574 1.0 14.23928565700366 -6.481711009288927 2.3805825873848767 0.915382866794013 1.2821094721810138 0.8171057220846425 0.07611082813248908 0.12221466984732664 1.3790294308132762 0.02821077623791472 0.031095038442644825 3.2982911594236465e-07 6.481711009288927 0.36672660538700075 SSSYS(ph)EANEPDLQMANGGK ddPTM_PC-9_AZD4547_30min_R2 1 SSSYSEANEPDLQMANGGK 19 0 A0A3B3ITG3;Q5VWQ8-2;Q5VWQ8;H0Y3A3;Q5VWQ8-3;Q5VWQ8-4;Q5VWQ8-5 A0A3B3ITG3 DAB2IP Disabled homolog 2-interacting protein 1 S(0.038)S(0.038)S(0.306)YS(0.617)EANEPDLQMANGGK 195.77 7.149299999999999e-59 0.0 9278.5 10319.0 13642.0 16915.0 14969.0 14610.0 12042.0 15361.0 12859.0 12992.0 True False 12228.869995210822 13654.41495095675 13461.098166475544 13015.508084144882 12890.812733748095 13696.434390407705 13113.714671554906 12987.310410664011 13538.700487831202 12537.154034457033 0.9754103651914202 1.089115991829489 1.073696480834418 1.0381549152521492 1.0282088501360889 1.092467584969006 1.0459881593153644 1.0359057865102217 1.0798862684961454 1.0 13.613922269446942 -4.745591238997919 24.938782888543148 1.0551466819569282 0.9754101366023931 0.40702112684534497 0.028306399434681728 877.9940085068961 1381542.2878203555 0.006768121554669998 0.17091215458206346 1.796423637867607e-05 4.745591238997919 -0.07973654535453512 SST(ph)DFSELEQPR ddPTM_PC-9_AZD4547_30min_R2 2 SSTDFSELEQPR 12 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 SS(0.003)T(0.997)DFSELEQPR;SS(0.012)T(0.988)DFSELEQPR 215.02 2.288e-10 34197000.0 29201.0 31711.0 44171.0 64027.0 45469.0 35670.0 34184.0 39385.0 31578.0 43436.0 True False 38486.310581468046 41960.960607596586 43585.2636791813 49266.56435728907 39156.414202070395 33439.5492611802 37226.30977681724 33298.95322726398 33247.148612235294 41915.31886088944 0.9181920030048739 1.0010889037217783 1.039840918873459 1.1753832655024596 0.9341790845496027 0.7977882590410672 0.8881313750794951 0.7944339714503457 0.7931980363212199 1.0 15.355189983989641 -6.517438200007285 9.54816586001295 0.8462612375127524 1.0346725893394688 0.5108605493263048 0.08231853129245995 0.10652135381535756 130.12467797838164 0.026554072515472652 0.027964401386324136 3.0378183419570645e-07 6.517438200007285 0.18841135182671642 SST(ph)DFSELEQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSTDFSELEQPR 12 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 S(0.025)S(0.025)T(0.95)DFSELEQPR;SS(0.003)T(0.997)DFSELEQPR 211.22 4.5602999999999995e-08 26943000.0 29596.0 31609.0 34854.0 32125.0 39493.0 34334.0 32211.0 22936.0 32722.0 25228.0 True False 34606.018252354894 34746.93262339651 35685.05154453109 30325.140400655255 31754.630152872647 32533.46459844738 29159.740892555 22333.954302700786 33200.49734605795 29801.636695261896 1.1612120034285511 1.1659404139008533 1.1974191857121923 1.0175662736495472 1.0655330939565897 1.0916670426903035 0.9784610553685145 0.7494203936205832 1.1140494626369442 1.0 14.863103944709941 -6.426811424790002 0.7813569402745026 0.9469317696676957 1.1793448845167014 0.3996718302364556 0.09567238053548179 0.6457999968865709 0.8711343204702171 0.05759026613891843 0.0813325728121482 3.742730662777373e-07 6.426811424790002 0.23241311484900573 SST(ph)DFSELEQPR ddPTM_PC-9_Lapatinib_30min_R1 2 SSTDFSELEQPR 12 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 SS(0.003)T(0.997)DFSELEQPR;S(0.006)S(0.026)T(0.968)DFSELEQPR 213.99 2.5907e-10 27890000.0 36971.0 29057.0 40512.0 28162.2 35351.0 27308.7 32884.0 26506.1 31303.0 25018.5 True False 36443.78676034894 28989.720301756744 37181.25974084235 30233.34213434517 33271.72368274008 26140.770560688958 34586.572617352256 27737.670171275386 27777.326504796627 29342.91438994422 1.241996151985441 0.9879632239833507 1.2671290672334963 1.0303455796028937 1.1338929473938777 0.8908716500787449 1.178702706817869 0.9452936338450775 0.9466451128765819 1.0 14.840724548689924 -6.459365948445249 0.6067585111729408 0.977526256317053 1.1647068175956905 0.2762581258978335 0.1075436525632885 1.2569961514318384 1.0064153387798285 0.07680646565073831 0.11934340719818083 3.472434412833155e-07 6.459365948445249 0.18718056127863747 SST(ph)FLRVVQPMFNHS(ph)IFT(ph)S(ph)AVSPAAER ddPTM_PC-9_AZD4547_30min_R2 1 SSTFLRVVQPMFNHSIFTSAVSPAAER 27 1 Q9Y6R1-3;Q9Y6R1-2 Q9Y6R1-3 4 S(0.156)S(0.156)T(0.694)FLRVVQPMFNHS(0.978)IFT(0.923)S(0.828)AVS(0.264)PAAER 42.106 0.038951 0.0 0.0 0.0 1266.7 1130.3 1189.3 691.68 758.78 1113.1 1932.0 815.52 True False 0.0 0.0 1249.9027303529224 869.7267979609195 1024.1862238123188 648.4291402571662 826.3099500483672 941.0959714934 2034.1215757438283 786.9688930249694 0.0 0.0 1.5882492197989138 1.1051603254835696 1.3014316485566892 0.8239577777524587 1.0499906125541734 1.1958490098331505 2.584754739066019 1.0 9.620162800392418 -5.253508439082064 24.59857814169387 1.3008774810933021 2.659703590564673e-07 0.5668171567501803 0.46488534945023535 346.23477272262653 1073872.4482061756 0.11910822765345772 0.30294152092040944 5.578167627053556e-06 5.253508439082064 -1.300877215122943 SST(ph)GPEPPAPTPLLAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTGPEPPAPTPLLAER 17 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.001)S(0.049)T(0.947)GPEPPAPT(0.004)PLLAER 80.719 0.027353 0.0 6287.9 8820.3 8947.4 9974.7 12752.0 8141.0 7858.6 6905.1 7940.9 6065.0 True False 7352.317278314039 9695.921092668046 9160.739949203456 9415.849897413727 10253.337140997945 7714.071628588566 7114.176516663027 6723.84844155821 8057.020639793149 7164.536489486419 1.026209760966837 1.3533214754222136 1.2786228338213312 1.3142301544881505 1.4311235843441064 1.0767021202151126 0.9929709377714395 0.9384903617177615 1.1245696984887164 1.0 12.80665765684667 -6.919982186679726 6.482700726715641 1.0123701354711396 1.285707488164905 0.5930913846915036 0.10616514692526709 0.1442435084910387 9.389976023553537 0.037234608195415624 0.03278068585544367 1.2023137485312194e-07 6.919982186679726 0.27333735269376547 SST(ph)PEEVK ddPTM_PC-9_AZD4547_30min_R2 2 SSTPEEVK 8 0 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 1 SS(0.004)T(0.996)PEEVK;S(0.021)S(0.021)T(0.959)PEEVK 157.99 9.086700000000001e-05 111120000.0 1527560.0 1620690.0 1504940.0 1742910.0 1591850.0 1849230.0 1578510.0 1751600.0 1614510.0 1768730.0 True False 2013292.3047781703 2144546.3481796784 1484983.5122896736 1341109.0271910708 1370849.1048311125 1733597.3557682124 1718994.3320209347 1480930.4677637608 1699849.7025125087 1706807.30105951 1.179566260074238 1.2564665893147045 0.8700358332003043 0.7857413232053613 0.8031657141261057 1.0156960042835956 1.0071402500761857 0.8676611981003743 0.9959236180073272 1.0 20.702868756278754 -5.261124292226124 24.99999737062422 0.911267720923933 1.2180164473878756 0.67481074211547 0.0831493889393915 15.872936315968994 1259272.6522380563 0.023175837180148595 0.054049827587380396 5.481200741089221e-06 5.261124292226124 0.3067487264639426 SST(ph)PEEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTPEEVK 8 0 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 1 S(0.001)S(0.002)T(0.998)PEEVK 145.46 0.0034671999999999997 38268000.0 586590.0 690220.0 472050.0 621790.0 615200.0 543410.0 659030.0 502080.0 475100.0 470460.0 True False 685888.1013193968 758740.4800949332 483305.46225959505 586953.1221703783 494655.9762501514 514912.62298136833 596601.9074359857 488900.93199773366 482047.4386991044 555750.6738406904 1.2341651276450114 1.365253369557643 0.8696444017234566 1.0561446882539136 0.8900681538209845 0.926517316520558 1.073506404073215 0.8797127111318274 0.8673807543367666 1.0 19.0840782669397 -5.260279489149866 24.998637729124475 0.9469597306690792 1.2997092715421723 0.7705066266570935 0.07734853427537039 42.759133347732 921543.1675560984 0.01945520002491706 0.04591272886773975 5.4918733194727115e-06 5.260279489149866 0.35274954087309307 SST(ph)PEEVK ddPTM_PC-9_Lapatinib_30min_R1 2 SSTPEEVK 8 0 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 1 S(0.006)S(0.077)T(0.917)PEEVK;S(0.335)S(0.052)T(0.613)PEEVK 139.38 0.0067062 110566000.0 891860.0 1165710.0 1150650.0 1120250.0 1358120.0 1199360.0 1186920.0 1120830.0 1103250.0 967490.0 True False 879141.9128529078 1163010.8701160084 1056047.9986374485 1202636.9220444502 1278238.0517666545 1148066.1686447146 1248372.9099558368 1172907.8535910859 978990.367262462 1134719.3574006115 0.7747659428907827 1.0249326078125665 0.9306688845571636 1.0598540636509652 1.126479462459169 1.0117622134116735 1.1001600543905237 1.0336545736541902 0.862759907000362 1.0 20.113904098778143 -4.212701170255514 1.5948117123001981 1.0272757965827861 7.247126992507143e-12 0.47845343554025654 0.07411228993714054 4.978764430784578 3.3672828666778636 0.02074798698439548 12.506720444450087 6.127718833361475e-05 4.212701170255514 -1.027275796575539 SST(ph)PEEVKK ddPTM_PC-9_AZD4547_30min_R2 2 SSTPEEVKK 9 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 1 S(0.007)S(0.242)T(0.751)PEEVKK;S(0.225)S(0.008)T(0.766)PEEVKK 99.28299999999999 0.014288999999999998 12081500.0 85447.0 72890.0 76792.0 96566.0 97553.0 92661.0 81103.0 89645.0 80498.0 95832.0 True False 112617.36859198987 96450.26705836195 75773.68790499857 74304.20062982757 84009.44983735216 86866.89302187323 88321.00988267027 75792.42508716715 84752.95994007586 92476.95084899057 1.2177885144146612 1.0429654759688127 0.819379177290702 0.8034888688226968 0.9084366327619805 0.9393356098399239 0.9550597102503228 0.8195817919097671 0.9164765832133941 1.0 16.49680620961597 -4.954604253146769 3.1603195736211407 0.890291366205514 1.2181284805573136 0.7270957116007548 0.0619833756469819 0.13816342111122476 2.588084236834562 0.016472914601401305 0.09174085339417754 1.1101860012607796e-05 4.954604253146769 0.32783711435179963 SST(ph)PGLK ddPTM_PC-9_Lapatinib_30min_R1 2 SSTPGLK 7 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 SS(0.035)T(0.965)PGLK;SS(0.021)T(0.979)PGLK 112.41 0.022431 25430300.0 569500.0 628930.0 640710.0 581490.0 547020.0 524200.0 489430.0 437230.0 560050.0 439130.0 True False 561378.8255664911 627473.751226343 588033.2970121218 624254.7143937739 514845.3590826988 501781.18796988326 514770.29060061846 457545.30198659044 496971.27141204866 515033.0353960563 1.0899860532922812 1.2183174827684997 1.14173898876201 1.2120673267370645 0.9996356033487965 0.9742699079176883 0.9994898486555609 0.888380493175048 0.9649308631821679 1.0 18.97430544745795 -6.365717704127263 4.5030231460848364 0.96318724488327 1.1672301972311645 0.8197639956954851 0.044784570886336444 0.08887826677345552 2.981341436334142 0.013913590943595969 0.015886615083970653 4.308065481806697e-07 6.365717704127263 0.2040429523478945 SST(ph)PLHS(ph)PSPIR ddPTM_PC-9_AZD4547_30min_R2 2 SSTPLHSPSPIR 12 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 2 S(0.104)S(0.167)T(0.729)PLHS(0.838)PS(0.162)PIR;S(0.026)S(0.022)T(0.954)PLHS(0.929)PS(0.069)PIR 154.23 0.0068411999999999995 13191000.0 39620.0 45966.0 76321.0 101319.0 99769.0 85090.0 75914.0 107428.0 79429.0 90859.0 True False 52218.3358528052 60823.61058587824 75308.9336727444 77961.46991294564 85917.7964882968 79769.30884871927 82670.19893509563 90827.4710498544 83627.45478248256 87678.05406532735 0.595569055557486 0.6937153342906043 0.858925696692961 0.8891788343621079 0.9799236240380174 0.9097978929742737 0.9428835963158985 1.0359202427346355 0.9538014463707558 1.0 16.419928158898806 -4.686730063410125 0.6782835122503919 0.9805686281216127 0.27999589567142263 0.9375027763168564 0.0330484230111099 0.7843041888885985 0.24991221872917546 0.014725478685434785 0.4376193258526998 2.0571688360350207e-05 4.686730063410125 -0.70057273245019 SST(ph)PLHS(ph)PSPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTPLHSPSPIR 12 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 2 S(0.002)S(0.07)T(0.928)PLHS(0.657)PS(0.343)PIR 139.19 0.0019109 10040000.0 29724.0 29199.0 59823.0 77439.0 82279.0 78964.0 73633.0 76342.0 72222.0 55836.0 True False 34755.686124239655 32097.683750531643 61249.40719999091 73100.34389062528 66157.02059474356 74822.9888318226 66657.94918324506 74338.10339103531 73278.11011939953 65958.62480246724 0.5269316367393334 0.48663361079248885 0.9286034598723141 1.1082757427030363 1.0030078824849742 1.1343927963310687 1.0106024706074779 1.1270414386846743 1.1109708599724852 1.0 16.009273699317202 -5.36099869601703 3.174714769740417 1.0716939786539874 0.4966499050344626 0.9477537741218083 0.05207478285828131 0.04564806110855388 0.8667908459898168 0.013531308967266932 0.03354904942214042 4.35513181325759e-06 5.36099869601703 -0.5750440736195248 SST(ph)PLHS(ph)PSPIR ddPTM_PC-9_Lapatinib_30min_R1 2 SSTPLHSPSPIR 12 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 2 S(0.002)S(0.004)T(0.994)PLHS(0.982)PS(0.018)PIR;S(0.019)S(0.008)T(0.972)PLHS(0.746)PS(0.254)PIR 168.82 0.0022823 32698000.0 75933.0 65250.0 85666.0 67410.0 75108.0 70423.0 59673.0 62859.0 82178.0 53905.0 True False 74850.18149559307 65098.91763394807 78622.8721603229 72367.55627316798 70690.29510800951 67411.17245403114 62762.57595776854 65779.65861806151 72922.24826729627 63222.407426102465 1.1839185589868868 1.029681093843808 1.243591874482497 1.1446504367578034 1.1181209002620769 1.066254437286728 0.9927267643379224 1.040448494387818 1.1534240981337425 1.0 15.948148351767049 -6.693243789190497 2.8139942311356587 1.0478416448342245 1.1471524281697854 0.3567707643515934 0.06411144451759689 0.3162378179356726 5.093253394980578 0.0232211843019074 0.02243269152608588 2.02654480865387e-07 6.693243789190497 0.09931078333556087 SST(ph)PLHSPSPIR ddPTM_PC-9_AZD4547_30min_R2 1 SSTPLHSPSPIR 12 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 S(0.122)S(0.145)T(0.649)PLHS(0.081)PS(0.002)PIR 89.74700000000001 0.015358000000000002 40611000.0 19779.0 27833.0 46965.0 78190.0 60329.0 65412.0 43256.0 79082.0 54874.0 68305.0 True False 26068.31057124263 36829.47294601989 46342.21341361413 60164.50352345773 51953.35970434153 61321.777299476285 47105.70020202449 66861.69402357478 57774.527612508726 65913.66274042385 0.39549176130452435 0.5587532449995822 0.7030744687351922 0.9127774276540052 0.7882031970964848 0.9303348463727319 0.7146576027421289 1.0143829252348544 0.8765182393221259 1.0 16.00828992103201 -4.912888335323608 0.8618144252801352 0.897022621452422 0.1602342933310386 0.7927373429192988 0.0862651242159669 0.8433128715369678 0.556281994011821 0.030704648966006054 0.5681787266116408 1.2221138465300271e-05 4.912888335323608 -0.7367883281213834 down SST(ph)PLHSPSPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTPLHSPSPIR 12 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 S(0.025)S(0.084)T(0.541)PLHS(0.343)PS(0.006)PIR 85.271 0.02046 22496000.0 21224.0 26583.0 23033.0 34873.0 42646.0 28774.0 39289.0 35938.0 24721.0 29886.0 True False 24816.80400689215 29221.98455907334 23582.194073138944 32919.178869791445 34289.82243687251 27265.04078626795 35567.261492272635 34994.66557945853 25082.497857462808 35304.09522255418 0.7029440593350152 0.8277222337765717 0.6679733306994186 0.9324464672517901 0.9712703928740343 0.7722911637981749 1.0074542703349139 0.9912353045405915 0.7104699242211069 1.0 15.107547923232541 -5.772972068604123 24.947009533121662 0.9124064274168339 0.7423641084137793 0.3982835532586564 0.1007828821454236 211.49752421543624 457502.2119172656 0.027519183073852118 0.04121208390745352 1.6866614985493972e-06 5.772972068604123 -0.17004231900305455 SST(ph)PLPTISSSAENTR ddPTM_PC-9_AZD4547_30min_R2 4 SSTPLPTISSSAENTR 16 0 P42166;G5E972;P42167;H0YJH7;P42167-2;P42167-3 P42166;G5E972 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 S(0.001)S(0.001)T(0.998)PLPTISSSAENTR;SS(0.005)T(0.995)PLPTISSSAENTR;S(0.015)S(0.091)T(0.894)PLPTISSSAENTR;S(0.007)S(0.007)T(0.985)PLPTISSSAENTR 217.79 8.9871e-22 1341548300.0 284746.0 364890.1 537698.0 545649.0 496638.0 394146.0 414280.0 534922.0 387653.0 334032.0 True False 375289.30491526716 482833.68901018566 530567.7731943686 419858.05324301345 427688.3862958899 369499.98831222666 451150.1174332973 452262.0961847033 408143.54617071553 322337.6413514276 1.1642739065218548 1.497912831358649 1.646000048179042 1.3025411847115445 1.3268335168761876 1.1463134952625047 1.399619714104169 1.4030694469580298 1.2661988356666616 1.0 18.298213145056266 -5.9660277448299945 24.999434683991797 1.282021792075321 1.4475846733581978 0.1934009900942696 0.15838556460079636 312.3934993213805 229881.67234534194 0.044197935275599946 0.06555577717211246 1.081364866278457e-06 5.9660277448299945 0.16556288128287688 SST(ph)PLPTISSSAENTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SSTPLPTISSSAENTR 16 0 P42166;G5E972;P42167;H0YJH7;P42167-2;P42167-3 P42166;G5E972 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 S(0.008)S(0.085)T(0.906)PLPTISSSAENTR;S(0.068)S(0.068)T(0.864)PLPTISSSAENTR;S(0.001)S(0.005)T(0.994)PLPTISSSAENTR;SS(0.007)T(0.993)PLPTISSSAENTR;S(0.006)S(0.006)T(0.988)PLPTISSSAENTR 235.71 1.2925999999999998e-36 1234805000.0 420682.0 512877.0 498154.0 471363.0 678426.0 387945.0 435056.0 340525.0 341642.0 309127.0 True False 491895.15375176235 563792.0390739894 510031.8806195644 444954.0592894658 545493.2954217917 367600.4812618593 393844.34614732204 331586.57956606115 346637.86792683665 365169.27805201383 1.3470332344926836 1.5439196913867552 1.396699862979483 1.2184871127797547 1.4938093870648477 1.0066577430139103 1.078525412236962 0.9080352578806773 0.9492525487794797 1.0 18.478205869916692 -6.771508739716443 24.760302976248973 0.9883732168839504 1.3977196914826846 0.8379116793106669 0.09048961510605312 72.713170703877 178798.66215577233 0.032668574686222154 0.029146986111329494 1.6923541872582634e-07 6.771508739716443 0.4093464745987342 SST(ph)PLPTISSSAENTR ddPTM_PC-9_Lapatinib_30min_R1 5 SSTPLPTISSSAENTR 16 0 P42166;G5E972;P42167;H0YJH7;P42167-2;P42167-3 P42166;G5E972 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 S(0.08)S(0.08)T(0.84)PLPTISSSAENTR;S(0.01)S(0.01)T(0.968)PLPT(0.007)IS(0.002)S(0.001)SAENTR;S(0.03)S(0.007)T(0.963)PLPTISSSAENTR;S(0.005)S(0.005)T(0.985)PLPTISS(0.002)S(0.002)AENT(0.001)R;S(0.047)S(0.081)T(0.872)PLPTISSSAENTR 214.89 1.4139000000000001e-21 795928500.0 255829.0 315896.0 194081.0 122781.5 150372.8 149897.0 154481.0 153763.0 191117.0 87837.2 True False 252180.83154670775 315164.562220592 178124.40935432495 131811.26109707696 141528.16754829956 143486.2547369736 162479.27029866198 160907.39031942945 169591.39090876956 103019.74298428776 2.447888377911888 3.0592637206312956 1.729031777738874 1.2794757323087127 1.3737965505299794 1.392803462525214 1.5771663332866477 1.561908287268495 1.6462028150723993 1.0 16.652561320350742 -5.387045530834801 4.483194311949855 1.4378519518141515 2.7442884939511103 0.8474119722877567 0.22480444017572024 0.07283267660087356 2.298010241916606 0.057194615113354316 0.12519657730821387 4.101611000081487e-06 5.387045530834801 1.3064365421369588 SST(ph)PLSEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSTPLSEAK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.02)S(0.02)T(0.96)PLSEAK;S(0.002)S(0.023)T(0.975)PLSEAK 114.89 0.0049187 45064000.0 676850.0 596680.0 595520.0 576940.0 599590.0 504780.0 572310.0 409200.0 433360.0 325620.0 True False 791427.3366031363 655914.4470792556 609719.455322177 544615.9222647162 482104.6436928301 478308.4481855966 518096.65363441565 398458.93358323927 439697.07016342785 384652.3283934974 2.0575134431358753 1.705213770104255 1.5851183271622813 1.4158653986037408 1.2533516843803933 1.2434825240321683 1.3469219224494213 1.0358937257637442 1.1431025830516226 1.0 18.55319551578971 -1.5228787452966368 0.29481645793890127 1.0402271624626145 9.469149301007036 0.9456691819679207 0.07232659793453793 11.093295255786831 0.157786210528371 0.07564996680425697 49.01911335125874 0.029999999998874087 1.5228787452966368 8.428922138544422 up SST(ph)PLSEAK ddPTM_PC-9_Lapatinib_30min_R1 1 SSTPLSEAK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 SS(0.025)T(0.974)PLSEAK 117.14 0.0045878 33726000.0 245080.0 273090.0 346030.0 266190.0 230520.0 228930.0 238670.0 203090.0 222890.0 180040.0 True False 241585.11425783212 272457.6768835998 317580.74911442783 285766.50058380864 216961.26681975758 219139.1975618952 251027.16477872114 212526.30281649643 197785.7810642466 211159.67411177923 1.1440873607805764 1.2902921830584562 1.503983894890431 1.3533194810318547 1.0274749084188644 1.0377890498442992 1.1888025771712345 1.0064720155989337 0.9366645496883413 1.0 17.687974819010904 -6.262157271774174 24.9953246570423 1.0412336390768617 1.3335232125061636 0.6611806575849458 0.10150105579214388 42.63043277351137 1484291.7395967266 0.032916252299667326 0.039600714697498256 5.468179069680351e-07 6.262157271774174 0.29228957342930184 SST(ph)PPGESYFGVSSLQLK ddPTM_PC-9_AZD4547_30min_R2 5 SSTPPGESYFGVSSLQLK 18 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.12)S(0.12)T(0.76)PPGESYFGVSSLQLK;S(0.042)S(0.042)T(0.916)PPGESYFGVSSLQLK;S(0.104)S(0.104)T(0.791)PPGESYFGVSSLQLK;S(0.057)S(0.057)T(0.886)PPGESYFGVSSLQLK;S(0.11)S(0.11)T(0.779)PPGESYFGVSSLQLK 152.94 6.8633e-05 1748807000.0 1041514.0 957565.0 1493660.0 1952429.0 1696590.0 1514372.0 1287912.0 1649178.0 1278713.0 1479531.0 True False 1372693.7871630131 1267079.1600458287 1473853.0924598917 1502326.6587773517 1461047.763775113 1419678.0794435653 1402533.6729838562 1394335.4344403415 1346303.1586356696 1427733.0700241888 0.9614498788206656 0.8874762283291243 1.0323029727362982 1.0522461728451098 1.023333979194276 0.9943581956951609 0.9823500641895857 0.9766079274305235 0.9429655913292394 1.0 20.44529484662587 -5.264225223938012 24.999854858619177 1.0014782520489287 0.9244630527683649 0.4522252881560873 0.033469843185791284 210.25386799800992 1886812.5459523797 0.009469432068456489 0.021174553666111845 5.442203484539497e-06 5.264225223938012 -0.07701519928056377 SST(ph)PPGESYFGVSSLQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSTPPGESYFGVSSLQLK 18 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.192)S(0.192)T(0.615)PPGESYFGVSSLQLK;S(0.008)S(0.008)T(0.985)PPGESYFGVSSLQLK;S(0.121)S(0.121)T(0.752)PPGES(0.003)Y(0.002)FGVSSLQLK 135.69 0.00018255 818250000.0 103554.0 116637.0 126592.0 130649.0 143662.0 118164.0 129495.0 127865.0 120498.0 98355.4 True False 121083.64691527115 128215.95053292118 129610.43338283342 123329.16009977317 115512.46238629571 111967.27182416664 117228.29613738802 124508.67923416615 122260.05529018048 116186.45543908216 1.042149417999559 1.1035361225917268 1.1155382345818234 1.061476224863715 0.9941990393782189 0.9636860974975893 1.008966972048236 1.071628175277689 1.052274594557046 1.0 16.826082369256618 -6.053422991700625 4.975386901631807 1.0162477800113505 1.0889554607377274 0.49288541666765917 0.0332691846077211 0.19287988191278235 10.347145440096202 0.011019594924883427 0.014793324384653198 8.842539495853187e-07 6.053422991700625 0.0727076807263769 SST(ph)PPGESYFGVSSLQLK ddPTM_PC-9_Lapatinib_30min_R1 6 SSTPPGESYFGVSSLQLK 18 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.097)S(0.097)T(0.806)PPGESYFGVSSLQLK;S(0.008)S(0.008)T(0.984)PPGESYFGVSSLQLK;S(0.13)S(0.13)T(0.738)PPGES(0.001)YFGVSSLQLK;S(0.061)S(0.061)T(0.878)PPGESYFGVSSLQLK;S(0.013)S(0.013)T(0.974)PPGESYFGVSSLQLK;S(0.099)S(0.099)T(0.801)PPGESYFGVSSLQLK 152.94 6.8996e-05 1280091200.0 174976.4 144361.2 176126.5 154606.8 176220.59999999998 162977.2 147992.0 146477.8 185395.5 123475.5 True False 172481.20444925784 144026.94051092566 161646.05903795065 165977.09982516547 165855.65077102973 156007.04507440893 155654.3016295827 153283.69333149915 164514.30648883551 144818.07565423808 1.1910198617820826 0.994537041458821 1.1162008492910125 1.1461076186473147 1.1452689867735857 1.0772622434708026 1.0748264740184559 1.058456913192751 1.136006715636958 1.0 17.143882159932545 -10.696717929874303 4.972193442525049 0.9999921258895023 1.1009329482256294 0.2576740066050379 0.05286919510206606 4.503055379535037e-06 7.482523580591119e-07 0.049951192938259836 0.012113998842156738 2.0103981230845172e-11 10.696717929874303 0.10094082233612711 SST(ph)PPLHVHVDENTPVHVHIK ddPTM_PC-9_AZD4547_30min_R2 1 SSTPPLHVHVDENTPVHVHIK 21 0 Q5BJF6-9;Q5BJF6-3;Q5BJF6-4 Q5BJF6-9 1 S(0.268)S(0.268)T(0.464)PPLHVHVDENT(0.001)PVHVHIK 62.658 0.0036811 15535000.0 22925.0 25927.0 34346.0 39825.0 35823.0 32086.0 22013.0 34303.0 29154.0 37918.0 True False 30214.673130377552 34307.39571988132 33890.54959872225 30643.961540116456 30849.594799990515 30079.657347749588 23972.11435516842 29002.25955452171 30695.02092092937 36590.502361340965 0.8257517984311776 0.9376038454210507 0.9262116508826264 0.8374840344496822 0.8431038878707524 0.822061885095344 0.6551458112937998 0.7926171460592878 0.8388794616102249 1.0 15.159181602530088 -6.185075056209028 1.7858062380692907 0.8016483332064104 0.8983218529098201 0.08642796177668932 0.08489789798533667 0.607703503876148 3.8276576822700537 0.02911806837628293 0.040962370051988634 6.530176862180347e-07 6.185075056209028 0.09667351970340976 SST(ph)PPRQS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 1 SSTPPRQSPSR 11 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 SS(0.001)T(0.999)PPRQS(0.98)PS(0.02)R 133.88 0.012471 151360000.0 331180.0 300320.0 432250.0 515610.0 475500.0 464790.0 423090.0 443850.0 385220.0 421070.0 True False 436488.35102806624 397392.56692231144 426518.0825728677 396744.08059509 409485.0327274507 435726.60782461206 460744.190366065 375263.18115833675 405581.9427577833 406328.46746373305 1.0742253767071468 0.9780081848628556 1.0496879168598658 0.9764122190884927 1.0077685063107211 1.0723506786132402 1.1339205279954667 0.9235463700111806 0.9981627555888233 1.0 18.632286918085406 -7.795356063902466 24.999891994393096 0.97064098884828 1.036975099646656 0.2828425201356555 0.04902487457928999 267.3987240689703 197095.43200102955 0.027496038745855027 0.013209599472356887 1.6019314806951554e-08 7.795356063902466 0.06633411079837603 SST(ph)PPRQSPS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTPPRQSPSR 11 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 S(0.002)S(0.019)T(0.978)PPRQS(0.008)PS(0.992)R 139.74 0.025421 100660000.0 412980.0 525570.0 525290.0 552390.0 674860.0 548180.0 505850.0 534600.0 522210.0 468280.0 True False 482889.35727319674 577745.1162288748 537814.9057734197 521441.37917254295 542626.0275230464 519432.4757842626 457932.2259631478 520567.3164555216 529846.333325741 553175.4570975584 0.872940675652633 1.0444156710426566 0.9722320447752082 0.942632888864014 0.9809293246127303 0.939001304413719 0.8278245538329922 0.9410528066210175 0.9578269001769848 1.0 19.077377623858865 -6.992173027569554 21.02777848363835 0.920570892454482 0.9659332517438268 0.04908760178494698 0.05686207755558447 57.40280319064758 154210.0412617781 0.0196899280301383 0.017303882301188546 1.0181856511741377e-07 6.992173027569554 0.045362359289344845 SST(ph)PSHGQTTATEPTPAQK ddPTM_PC-9_AZD4547_30min_R2 1 SSTPSHGQTTATEPTPAQK 19 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 S(0.01)S(0.01)T(0.929)PS(0.051)HGQTTATEPTPAQK 235.75 2.2138e-118 0.0 3454.0 3950.3 10900.0 22340.0 13876.0 12576.0 7661.3 14492.0 7665.1 12217.0 True False 4552.300152336928 5227.157222673171 10755.458878066514 17189.858149559375 11949.556917194765 11789.620731948473 8343.140858095298 12252.594393030597 8070.261537388207 11789.286548565387 0.3861387314307741 0.4433819808467759 0.9123078681445166 1.458091469636148 1.0135945774130735 1.000028346361903 0.7076883595734261 1.0392990570342517 0.6845419783583307 1.0 13.525188793033298 -5.2755585956791515 4.552658658992278 0.9914481095351745 0.40328015270297385 0.5618690116431602 0.19937734516215028 0.13642977013958932 7.639887584641188 0.05507882162799531 0.13430606182549257 5.302020521271781e-06 5.2755585956791515 -0.5881679568322007 SST(ph)PSHGQTTATEPTPAQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSTPSHGQTTATEPTPAQK 19 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 S(0.203)S(0.203)T(0.429)PS(0.15)HGQT(0.011)T(0.003)ATEPTPAQK;S(0.022)S(0.022)T(0.955)PSHGQTTATEPTPAQK 265.08 2.0325999999999994e-178 8139600.0 32672.9 34876.7 69527.0 73822.0 102268.0 80482.0 69010.0 60752.3 68552.0 54971.0 True False 38203.77665080975 38339.028283919564 71184.78736261568 69685.99267415308 82229.31953698077 76261.38223953628 62472.87321086649 59157.616497382674 69554.44331235766 64936.80714980343 0.5883223756701964 0.5904051949378237 1.0962163137833172 1.0731354948418343 1.2662975459708858 1.1743937773781834 0.9620564353702691 0.911002851755728 1.0711096890227718 1.0 15.986748830659655 -5.259673789652745 24.482409225820813 1.0731972397184442 0.5893637119332521 0.8000238491391528 0.09595937545720182 51.22893622544224 710341.1462880789 0.028044409156960243 0.06673896281638826 5.4995380395314234e-06 5.259673789652745 -0.48383352778519206 SST(ph)PTPR ddPTM_PC-9_AZD4547_30min_R2 1 SSTPTPR 7 0 A0A669KBK8;Q04724;F6T2C8;A0A669KAE5 A0A669KBK8 TLE1 Transducin-like enhancer protein 1 1 SS(0.001)T(0.999)PTPR 132.76 0.010469 8276600.0 60339.0 37033.0 27863.0 29254.0 24679.0 26903.0 17949.0 31910.0 53676.0 74475.0 True False 79525.54687083306 49003.19303021428 27493.518414639202 22509.94226979452 21252.7468405484 25220.75115709367 19546.426228179636 26979.04271885219 56513.203778274175 71867.65291842558 1.1065555036436168 0.6818532544236009 0.38255762221490824 0.3132138222928298 0.29572061946522227 0.35093327989604517 0.27197807962875997 0.37539896773135395 0.7863510422751708 1.0 16.133054950286017 -10.296901496913325 7.822945508657819 0.9999826179832145 0.48133221809217897 0.24122395900159277 0.2585877219559042 7.655256762099323e-10 0.0 0.2644942348420487 0.06414927456592294 5.047757736518004e-11 10.296901496913325 -0.5186503998910356 SST(ph)PTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSTPTPR 7 0 A0A669KBK8;Q04724;F6T2C8;A0A669KAE5 A0A669KBK8 TLE1 Transducin-like enhancer protein 1 1 S(0.017)S(0.017)T(0.966)PT(0.001)PR;S(0.005)S(0.12)T(0.875)PTPR;S(0.015)S(0.066)T(0.918)PT(0.001)PR 118.74 0.016606 21647600.0 33067.6 56889.8 68177.0 37106.0 173980.0 167780.0 48747.8 79491.0 140385.0 198873.0 True False 38665.29156512941 62537.443372409885 69802.59824271222 35027.07111927511 139889.86792588007 158981.32144019034 44130.055480490926 77404.44547767653 142437.8650426732 234927.10062219808 0.16458421128394907 0.2661993580424785 0.29712450397524137 0.1490976180547364 0.5954607516773737 0.6767261887586941 0.18784574177952934 0.32948282796098427 0.6063066571095048 1.0 17.841853623197913 -14.522878745267485 0.1287240413956652 3.1379344927242756 0.09120772428253489 0.6260808176957968 0.16256209693751839 106.69133396353304 0.8663267816736784 58.7632669023415 1.3781065897013938 3.000000000088779e-15 14.522878745267485 -3.0467267684417405 SST(ph)PTPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSTPTPR 7 0 A0A669KBK8;Q04724;F6T2C8;A0A669KAE5 A0A669KBK8 TLE1 Transducin-like enhancer protein 1 1 S(0.005)S(0.126)T(0.869)PTPR 107.01 0.024380000000000002 10718000.0 18142.0 25404.0 14791.0 23908.0 25087.0 10460.0 40748.0 37097.0 20853.0 22690.0 True False 17883.291753164656 25345.178598817125 13574.941074911114 25666.274074749996 23611.431982939674 10012.65018345093 42857.73205850474 38820.66204925671 18504.31554817505 26611.936267475456 0.6720026522467377 0.952398891387451 0.5101072292699769 0.9644647355524736 0.8872496817075677 0.3762465865998702 1.6104702652127028 1.4587687892783097 0.695338939721971 1.0 14.699785863297693 -7.26059094222522 24.999670828375297 1.2293752191292906 0.745528638030291 0.37627717376106384 0.29046075622797796 81.02911229975233 2387613.768732916 0.11428225365020438 0.08327051468455088 5.4879362497503565e-08 7.26059094222522 -0.4838465810989996 SST(ph)PTSYQAPK ddPTM_PC-9_Lapatinib_30min_R1 2 SSTPTSYQAPK 11 0 O94929 O94929 ABLIM3 Actin-binding LIM protein 3 1 S(0.018)S(0.023)T(0.825)PT(0.128)S(0.003)Y(0.002)QAPK;S(0.019)S(0.019)T(0.962)PTSYQAPK 190.78 7.352800000000001e-36 3060200.0 70223.0 61889.0 61538.0 54777.0 57174.0 54086.0 48114.0 41032.0 54834.0 43181.0 True False 69221.60714267903 61745.699822948816 56478.583183549454 58805.483310715324 53811.13772840885 51772.86786062403 50605.107496389945 42938.49651468047 48658.01749238148 50644.77831493419 1.3668064003010332 1.2191918274176978 1.1151906487246876 1.1611361579082022 1.0625209452746476 1.0222745480032476 0.9992166849206535 0.8478365972434065 0.9607706680005971 1.0 15.628125908447664 -4.637653698727628 0.39080480931434447 0.9238820156920606 1.7020641517886743 0.857377279516974 0.0525916439767386 2.3541357489410655 0.2613566485031442 0.04622449880109551 0.8829285967296665 2.303277691690674e-05 4.637653698727628 0.7781821360966137 SST(ph)SPCGTSK ddPTM_PC-9_AZD4547_30min_R2 2 SSTSPCGTSK 10 0 O75376-2;O75376;A0A088AWL3;O75376-3;H0Y459 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 SS(0.001)T(0.915)S(0.082)PCGT(0.002)S(0.001)K;S(0.259)S(0.259)T(0.431)S(0.051)PCGTSK 145.23 0.00033478 13346400.0 208740.0 173296.0 109427.0 88357.0 94757.0 121571.0 99255.0 115215.0 210820.0 201306.0 True False 275114.977938277 229310.5430120166 107975.92648166837 67987.65875204197 81601.62617487933 113969.14615169438 108088.50271758711 97411.16912731306 221963.51480243975 194258.33821277722 1.4162325307083343 1.1804411852882506 0.5558367660048599 0.34998579405931585 0.4200675601656724 0.5866885674006972 0.5564162841710012 0.501451675246061 1.1426202697117493 1.0 17.567616999659485 -5.153960153054148 3.599142800556753 0.5976744601011547 1.370381792965874 0.5510083933193375 0.23915758748601823 0.16387781913694519 3.8142979445952174 0.06196256954032077 0.19828064926616393 7.015196605860981e-06 5.153960153054148 0.7727073328647193 SST(ph)SPCGTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSTSPCGTSK 10 0 O75376-2;O75376;A0A088AWL3;O75376-3;H0Y459 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 S(0.021)S(0.003)T(0.879)S(0.096)PCGTSK;S(0.02)S(0.002)T(0.836)S(0.142)PCGTSK 133.42 0.00027831 9904900.0 50247.0 114408.0 93582.0 39514.0 182571.0 170392.0 69599.0 78699.0 149906.0 208030.0 True False 58752.824676512864 125765.67014386898 95813.34979171136 37300.15868611646 146797.5231468895 161456.3435620273 63006.07886687573 76633.23463848326 152098.09165571057 245744.19223542625 0.23908123379057059 0.5117747402281791 0.38989059688507666 0.15178449731329727 0.5973590741312637 0.6570098039482859 0.2563888826577641 0.3118414882621828 0.6189285299975616 1.0 17.90679779565309 -8.584495522334503 3.6460464997691178 0.9995539511787801 0.3983822553492746 0.6016146983543162 0.152993591805502 0.20435247102166373 7.452277496385966 0.1521274097732536 0.040027470428439856 2.6031816705746456e-09 8.584495522334503 -0.6011716958295055 SST(ph)SPCGTSK ddPTM_PC-9_Lapatinib_30min_R1 1 SSTSPCGTSK 10 0 O75376-2;O75376;A0A088AWL3;O75376-3;H0Y459 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 S(0.109)S(0.186)T(0.641)S(0.065)PCGTSK 129.0 0.00063784 11507000.0 41733.0 130160.0 65284.0 81817.0 136950.0 69183.0 209630.0 197890.0 108480.0 97152.0 True False 41137.87976710513 129858.62251700665 59916.601523527665 87834.09511351086 128894.87025405932 66224.20436344997 220483.61567253247 207084.69183296245 96261.84005495766 113944.59375309704 0.3610340641193167 1.139664623302736 0.5258397923938284 0.7708491664276395 1.1312065452912805 0.5811965463403127 1.9350072558097096 1.8174156843429339 0.8448127013690919 1.0 16.797972950153458 -7.246985318822998 24.996075341916857 1.467426906166764 0.7771332727179244 0.3996232333035886 0.3845483935814335 750.9092724766062 1298583.9663358252 0.14361210455126489 0.11072173431411095 5.6625843088804886e-08 7.246985318822998 -0.6902936334488395 SST(ph)VASLDTDSTK ddPTM_PC-9_Lapatinib_30min_R1 1 SSTVASLDTDSTK 13 0 C9IZZ8;C9J6Y2;C9J0J6;C9JZ07;G3V1A3;C9J5T5;C9JBU8;A8MPU2;O14713-2;O14713 C9IZZ8 ITGB1BP1 Integrin beta-1-binding protein 1 1 S(0.001)S(0.04)T(0.911)VAS(0.031)LDT(0.017)DSTK 212.1 2.2640999999999997e-10 15957000.0 45831.0 51768.0 46268.0 38060.0 47317.0 48053.0 44312.0 39483.0 51086.0 44528.0 True False 45177.44153562396 51648.13437661647 42464.02363964491 40859.05936443805 44533.90708880125 45997.88520701414 46606.2585397188 41317.52431977795 45332.15672057121 52224.60547016952 0.865060465826384 0.988961695576957 0.8131037708633374 0.7823718149058413 0.8527380281357767 0.8807703723733814 0.892419542859737 0.7911505304406435 0.8680229618290703 1.0 15.6724420680696 -8.576824332188298 21.09182179375707 1.0000000003689318 0.8584146104889228 0.364722550538637 0.05579882017874537 8010.78803853967 3132079.1109395456 0.05668164533556011 0.014635137814270376 2.6495716473443984e-09 8.576824332188298 -0.14158538988000902 SST(ph)VPSSNTASGGMTR ddPTM_PC-9_AZD4547_30min_R2 2 SSTVPSSNTASGGMTR 16 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;A2SY06;H0YKP9 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 SS(0.006)T(0.994)VPSSNTASGGMTR;SS(0.001)T(0.999)VPSSNTASGGMTR 127.07 9.889700000000001e-05 8852100.0 23571.0 24321.0 28584.0 36873.0 31467.0 35251.0 30085.0 34726.0 30039.0 31270.0 True False 31066.087692742833 32182.28762692304 28204.957483546168 28372.49953217112 27098.35020995731 33046.74939741698 32762.50671763239 29359.89462409468 31626.80021416608 30175.246817847248 1.0295222398767157 1.0665128216246675 0.9347051128961853 0.9402574137484806 0.8980324294789165 1.095160864694945 1.08574113462611 0.9729794358046369 1.0481041101364017 1.0 14.881077951074168 -6.774111188943853 24.99169781334044 1.0415423086373448 0.9749202864831511 0.26071386072965386 0.05603505938600164 364.2560953110739 718391.3863529704 0.02145688801172417 0.0190475487373313 1.6822433146268642e-07 6.774111188943853 -0.06662202215419366 SST(ph)VPSSNTASGGMTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTVPSSNTASGGMTR 16 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;A2SY06;H0YKP9 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 SS(0.001)T(0.993)VPS(0.004)S(0.001)NTAS(0.001)GGMTR 89.46600000000001 0.014318 3797400.0 16767.0 19295.0 18938.0 19726.0 23871.0 18147.0 21849.0 19921.0 17621.0 12383.0 True False 19605.321936654767 21210.480083787395 19389.553742764943 18620.81617255488 19193.64890940731 17195.339374032286 19779.30454693846 19398.09485804421 17878.67378934315 14627.939876225942 1.3402654169038741 1.4499977620402806 1.3255150012120172 1.272962312541246 1.3121224910557492 1.1755134024018659 1.3521592728915144 1.3260988917223375 1.222227732724036 1.0 13.836438981586861 -14.227840436378024 0.15101855393961422 1.916629484037832e-12 1.4061780233967212 0.7142615526640217 0.06225047189206403 70.52835204474941 0.681981996500112 21.377180512341948 0.3322166825615139 5.917790190679915e-15 14.227840436378024 1.4061780233948045 SST(ph)VPSSNTASGGMTR ddPTM_PC-9_Lapatinib_30min_R1 2 SSTVPSSNTASGGMTR 16 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;A2SY06;H0YKP9 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 S(0.001)S(0.01)T(0.989)VPS(0.001)SNTASGGMTR;S(0.051)S(0.051)T(0.898)VPSSNTASGGMTR 102.15 0.0058845 6249300.0 17650.9 25337.9 23451.3 17952.4 23642.7 22972.7 18994.4 22666.4 22007.3 16951.4 True False 17399.19492922137 25279.23164930594 21523.224638635864 19272.679383450803 22252.08286933663 21990.211172979263 19977.837091687026 23719.56369176141 19528.606126857183 19881.426903679312 0.8751481980401228 1.271499866271052 1.0825794719318016 0.9693810950704019 1.1192397294793062 1.1060680543462247 1.0048492589830096 1.1930513743644728 0.982253749766983 1.0 14.27913368338059 SST(ph)VTEAPIAVVTSR ddPTM_PC-9_AZD4547_30min_R2 1 SSTVTEAPIAVVTSR 15 0 Q8TD19 Q8TD19 NEK9 Serine/threonine-protein kinase Nek9 1 S(0.005)S(0.005)T(0.991)VTEAPIAVVTSR 157.37 0.00055787 13339000.0 19790.0 23621.0 27947.0 41552.0 34042.0 33005.0 21386.0 31249.0 23056.0 24073.0 True False 26082.808342428438 31256.026316169147 27576.404519754593 31972.828372000495 29315.855907692734 30941.192132471333 23289.312569828384 26420.18508058327 24274.693090243123 23230.211597250927 1.1227968472536465 1.3454903837323633 1.1870922657896925 1.376346842048747 1.2619711096889872 1.3319375935487787 1.0025441426708508 1.13732003559149 1.044962203147379 1.0 14.50371467484616 -7.26174828158784 24.999999938709692 1.057649926353425 1.2749002630707775 0.6589718055700728 0.07899934638816075 17.100879145987477 1383909.725020405 0.02980733440780267 0.021522781341211515 5.4733310692177944e-08 7.26174828158784 0.2172503367173526 SST(ph)VTEAPIAVVTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTVTEAPIAVVTSR 15 0 Q8TD19 Q8TD19 NEK9 Serine/threonine-protein kinase Nek9 1 S(0.007)S(0.001)T(0.992)VTEAPIAVVTSR 154.13 0.00041374 6494700.0 16292.0 20776.0 25599.0 34285.0 49687.0 57483.0 57621.0 59956.0 64139.0 58137.0 True False 19049.9138183324 22838.503976199383 26209.377244748128 32364.122603469714 39951.18903111394 54468.49028696191 52162.721740086105 58382.21852863306 65076.91153593334 68676.77788776117 0.27738508421967284 0.3325506041288727 0.3816337640007261 0.47125278149132993 0.5817277726163331 0.7931136544579895 0.7595394446917111 0.8501013053356614 0.9475824803878959 1.0 16.06753473347316 -6.507672827975831 0.5043511134853416 0.9920496714062121 0.20523320573517975 0.9814710260572488 0.03418564749574742 0.1418469982532454 0.07482775517767797 0.030544592353936775 0.05174050732058072 3.1068992626508514e-07 6.507672827975831 -0.7868164656710324 down SST(ph)VTEAPIAVVTSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSTVTEAPIAVVTSR 15 0 Q8TD19 Q8TD19 NEK9 Serine/threonine-protein kinase Nek9 1 S(0.004)S(0.01)T(0.972)VT(0.014)EAPIAVVTSR 88.78 0.011592 7984400.0 19540.0 11498.0 19184.0 13598.0 37982.0 59332.0 63236.0 49887.0 81914.0 57185.0 True False 19261.356016802867 11471.377087435018 17606.7655723815 14598.042281598227 35747.9734354851 56794.50866964728 66510.0506638756 52204.9321414473 72687.9827273396 67069.35105577715 0.28718566250603006 0.1710375440772497 0.2625158182571219 0.21765593451855528 0.5330001390017308 0.8468027165256905 0.9916608647154433 0.7783724058703342 1.0837734610983458 1.0 16.033366022557228 -6.604967026269463 1.9564984569080834 0.9481300649321355 0.22570639549609545 0.9465956871286378 0.07950557660394053 0.06592238920759846 0.5147631737155297 0.028875861693882864 0.02955229675297842 2.4833216438878936e-07 6.604967026269463 -0.72242366943604 down SSTELHPDLLTDCLTVQSLQPAT(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 SSTELHPDLLTDCLTVQSLQPATSPR 26 0 Q8NEA6;Q8NEA6-2 Q8NEA6 GLIS3 Zinc finger protein GLIS3 1 SSTELHPDLLTDCLTVQS(0.001)LQPAT(0.499)S(0.499)PR 118.41 9.3602e-06 0.0 7993.8 6642.2 10278.0 6374.3 9580.9 8876.0 7529.0 9098.7 11105.0 6254.5 True False 7879.806946116621 6626.820393995547 9432.982514227333 6843.087286041449 9017.370298774134 8496.394170966583 7918.814780320069 9521.4588184374 9854.237959165781 7335.581991402608 1.074189744638101 0.9033803182572647 1.2859214886130241 0.932862217893772 1.229264468632837 1.1582440467470014 1.0795073641874655 1.2979827407827582 1.343347803993612 1.0 12.840695715837088 -5.959523165411646 0.6618945508347146 1.2067618104302087 1.0027463157541106 0.14362465931062995 0.13772074353444355 1.8046653905192918 1.4868115834177607 0.0801176103811559 0.22680775039814163 1.097682737950971e-06 5.959523165411646 -0.20401549467609814 SSTELHPDLLTDCLTVQSLQPATS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 SSTELHPDLLTDCLTVQSLQPATSPR 26 0 Q8NEA6;Q8NEA6-2 Q8NEA6 GLIS3 Zinc finger protein GLIS3 1 SSTELHPDLLTDCLTVQS(0.001)LQPAT(0.273)S(0.727)PR 111.38 1.5511000000000002e-10 3547700.0 6620.0 8055.2 25033.0 40107.0 28832.0 25457.0 18142.0 28040.0 24219.0 25590.0 True False 8725.022295445988 10658.885871978562 24701.046063728376 30860.95079697302 24829.174476546512 23865.16976568164 19756.602854289078 23707.062295099204 25499.16689593154 24694.101888989793 0.3533241392891539 0.4316369115141205 1.0002812078272698 1.2497296291926616 1.0054698319527442 0.966431979302809 0.8000535084492315 0.9600293382473377 1.0326015098893189 1.0 14.591878879188574 -5.245074778687975 5.370786899718435 1.0021143234765606 0.38126445968125017 0.8468239143605806 0.10379105426992656 0.06600088974063045 6.419521102540285 0.03004636446039847 0.07665380494300288 5.68754991736605e-06 5.245074778687975 -0.6208498637953104 down SSTELHPDLLTDCLTVQSLQPATS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 SSTELHPDLLTDCLTVQSLQPATSPR 26 0 Q8NEA6;Q8NEA6-2 Q8NEA6 GLIS3 Zinc finger protein GLIS3 1 SSTELHPDLLTDCLTVQSLQPAT(0.052)S(0.948)PR 176.0 8.84e-18 2167900.0 10081.0 8100.7 15505.0 9294.8 9716.6 10848.0 9562.1 11866.0 13551.0 6369.5 True False 9937.243091371014 8081.943326855521 14230.238751030822 9978.370598543856 9145.088691570607 10384.056327923108 10057.178750285366 12417.337678962731 12024.743681643897 7470.459588174738 1.3302050528592695 1.0818535635543391 1.9048679111465088 1.3357104045297268 1.2241668111084758 1.3900157286655306 1.3462597088678774 1.6621919351010994 1.609639077718632 1.0 12.866981286068112 SSTETCY(ph)SAIPK ddPTM_PC-9_AZD4547_30min_R2 2 SSTETCYSAIPK 12 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;A0A0A0MT44 O75369-2 FLNB Filamin-B 1 SST(0.01)ET(0.296)CY(0.459)S(0.234)AIPK;SST(0.001)ET(0.01)CY(0.688)S(0.301)AIPK 169.93 0.0014765000000000002 35149000.0 26941.0 45881.0 49377.0 75300.0 68442.0 49522.0 42519.0 60984.0 56129.0 50509.0 True False 35507.677592388274 60711.13599814385 48722.22871764134 57940.74837340282 58940.00969491524 46425.381511414766 46303.108629782684 51560.32407290763 59095.86435037544 48740.69528374311 0.7285016634596808 1.245594377444044 0.999621126329974 1.1887550646559668 1.2092566458438272 0.9524973175115827 0.949988677022967 1.0578495807815236 1.2124542747359244 1.0 15.572839210734907 -4.745008090713649 24.93847142337145 1.0876881025582712 0.728500600049556 0.4976815427277531 0.109118052447388 841.1073993139322 1276513.867114544 0.02765901922176098 0.7348649200710623 1.7988374032733416e-05 4.745008090713649 -0.35918750250871523 SSTETCY(ph)SAIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSTETCYSAIPK 12 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;A0A0A0MT44 O75369-2 FLNB Filamin-B 1 SSTET(0.002)CY(0.958)S(0.039)AIPK;SST(0.001)ET(0.199)CY(0.688)S(0.111)AIPK;S(0.004)S(0.004)T(0.029)ET(0.306)CY(0.606)S(0.05)AIPK;SSTETCY(0.783)S(0.217)AIPK 182.64 0.00036065 26829300.0 63863.0 48803.0 76162.0 68255.4 122313.0 88243.0 99825.0 84775.0 95509.0 69568.0 True False 74673.74454825441 53647.8393122092 77977.99092599348 64431.27122499242 98346.64568121721 83615.3817370766 90368.85332958652 82549.74607653744 96905.63843972413 82180.12770001497 0.9086593880802745 0.6528079331787097 0.9488667529288747 0.7840249586881657 1.1967205264053062 1.0174647335947298 1.0996436225977058 1.0044976612578616 1.1791857855643912 1.0 16.326501951866106 -6.250450977030743 24.997355165164894 1.0807071509858583 0.8203393985424049 0.6329869836682755 0.09671717538531138 447.18728311534136 1017299.3038124668 0.02680398539981227 0.034273661838235055 5.61757685736269e-07 6.250450977030743 -0.26036775244345345 SSTETCY(ph)SAIPK ddPTM_PC-9_Lapatinib_30min_R1 2 SSTETCYSAIPK 12 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;A0A0A0MT44 O75369-2 FLNB Filamin-B 1 SST(0.005)ET(0.083)CY(0.592)S(0.32)AIPK;SSTET(0.002)CY(0.677)S(0.321)AIPK 192.12 0.00010175 36004000.0 82998.0 65992.0 95347.0 58873.0 89780.0 68933.0 103669.0 62823.0 92468.0 71277.0 True False 81814.433300031 65839.19957853625 87507.93771006344 63202.71681457071 84499.31691427124 65984.89628067147 109036.47356368719 65741.98592663712 82053.28010879253 83597.13447936754 0.9786750922691432 0.7875772296332227 1.0467815464615133 0.7560392734534419 1.0107920258334497 0.7893200728902626 1.304308745063484 0.7864143470475389 0.981532209444858 1.0 16.351165870381223 SSTETCYSAIPK ddPTM_PC-9_Lapatinib_30min_R1 2 SSTETCYSAIPK 12 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;A0A0A0MT44 O75369-2 FLNB Filamin-B 0 ; 143.89 0.00041488 17544400.0 38814.0 35256.0 37164.0 38782.0 35184.0 32720.0 32233.0 30425.0 27872.0 30608.0 False True 38260.50524238413 35174.36689812219 34108.51937718859 41634.15765295944 33114.54629440548 31320.64187404536 33901.867022719714 31838.656571923213 24732.761854828335 35898.55201740363 1.0657952227108054 0.9798268988974722 0.9501363553787008 1.1597726179255137 0.9224479661004583 0.872476468099914 0.9443797902011223 0.8869064288857061 0.6889626590743239 1.0 15.131638033084105 -6.505155164824515 21.645737781424494 0.8780213882417492 1.0299236476508256 0.4116368479508513 0.09064123433899653 135.65024170118434 165669.37061358258 0.028227946767785516 0.03123720735846375 3.124962680322225e-07 6.505155164824515 0.1519022594090763 SSTFNRVNANMS(ph)HPLVLGK ddPTM_PC-9_Lapatinib_30min_R1 1 SSTFNRVNANMSHPLVLGK 19 1 A8K979-2;A8K979 A8K979-2 ERI2 ERI1 exoribonuclease 2 1 S(0.003)S(0.003)T(0.003)FNRVNANMS(0.992)HPLVLGK 44.963 0.045286 5619500.0 9034.0 16865.0 24389.0 23956.0 19617.0 17607.0 12863.0 13889.0 23438.0 12840.0 True False 8905.173503367298 16825.950128682518 22383.83056426254 25717.80415487331 18463.166628505907 16853.989653921664 13528.983200857621 14534.333644287311 20798.1656269183 15059.376891775448 0.5913374482466657 1.1173071933588348 1.4863716291267854 1.7077601775753997 1.2260246065419487 1.1191691246618796 0.8983760283100666 0.9651351280161609 1.381077436097442 1.0 13.87837445674766 -6.822952377577976 4.033703499698215 1.053831598784024 1.2619154973665834 0.05885821755132903 0.29385747812485374 0.607453041885522 19.80744753852785 0.11478743767301423 0.10305092809075377 1.5033068016772044e-07 6.822952377577976 0.20808389858255927 SSTFPQTDVLSS(ph)SLEAEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SSTFPQTDVLSSSLEAEHR 19 0 D4PHA4;Q86WP2-4;Q86WP2-3;Q86WP2;Q86WP2-2 D4PHA4 GPBP1 Vasculin 1 SSTFPQTDVLS(0.008)S(0.622)S(0.37)LEAEHR;SSTFPQTDVLS(0.008)S(0.687)S(0.305)LEAEHR;SSTFPQTDVLS(0.007)S(0.648)S(0.345)LEAEHR 215.59 5.6134e-28 36781100.0 80406.0 89220.0 111219.0 130912.0 144129.0 157321.0 150355.0 150958.0 154554.0 129363.0 True False 94017.14770911091 98077.17196556147 113870.88276040644 123577.42506243037 115887.9570886833 149070.80981220765 136112.28592406632 146995.51245322253 156814.0598625586 152815.4878630554 0.6152331090508559 0.6418012554686386 0.745152761364418 0.8086708146570423 0.7583521716891388 0.9754954284856027 0.8906969301831661 0.9619150160025115 1.0261660127217374 1.0 17.221431242489068 -5.829020851263123 0.418633403976739 1.0222669997054894 0.4971676507453305 0.9019978652691903 0.044541818879028514 0.6620919110010338 0.16979675481746603 0.03929318748510999 0.16051067225646393 1.4824469084815049e-06 5.829020851263123 -0.525099348960159 SSTFPQTDVLSS(ph)SLEAEHR ddPTM_PC-9_Lapatinib_30min_R1 2 SSTFPQTDVLSSSLEAEHR 19 0 D4PHA4;Q86WP2-4;Q86WP2-3;Q86WP2;Q86WP2-2 D4PHA4 GPBP1 Vasculin 1 SSTFPQTDVLS(0.026)S(0.77)S(0.204)LEAEHR;SSTFPQTDVLS(0.031)S(0.485)S(0.485)LEAEHR 192.11 5.2978e-48 3521300.0 26481.0 23953.4 34713.0 30657.0 37360.0 36173.0 29824.0 32293.0 40451.0 28940.0 True False 26103.37608397934 23897.937373992525 31859.031136054997 32911.618048754004 35162.558252586074 34625.96511338151 31368.140790047244 33793.4506713925 35894.982412086014 33942.24043987392 0.7690528305053836 0.7040766037918412 0.9386248734078361 0.969635994036823 1.0359527773328296 1.0201437696700886 0.9241623529717639 0.9956163834044782 1.0575313222375884 1.0 15.05079417615708 -5.381539585756194 3.332741069540108 0.9977775347569589 0.7347965848096889 0.8790253513039208 0.03843757429434899 0.07719661941818876 1.5770341148856255 0.010806299955901724 0.025738468709899893 4.153941865138541e-06 5.381539585756194 -0.26298094994726995 SSTFPQTDVLSSS(ph)LEAEHR ddPTM_PC-9_AZD4547_30min_R2 5 SSTFPQTDVLSSSLEAEHR 19 0 D4PHA4;Q86WP2-4;Q86WP2-3;Q86WP2;Q86WP2-2 D4PHA4 GPBP1 Vasculin 1 SSTFPQTDVLS(0.003)S(0.203)S(0.794)LEAEHR;SSTFPQTDVLS(0.002)S(0.224)S(0.775)LEAEHR;SSTFPQTDVLS(0.002)S(0.087)S(0.911)LEAEHR;SSTFPQTDVLS(0.028)S(0.151)S(0.821)LEAEHR;SSTFPQTDVLS(0.01)S(0.433)S(0.557)LEAEHR 221.83 7.8098e-29 68607900.0 187021.0 151630.8 266899.0 374612.0 347920.0 291105.0 235822.0 303033.0 242356.0 299794.0 True False 246489.78772154194 200642.49079809402 263359.7448712917 288250.9910977055 299617.31353635126 272902.15833125426 256809.70115225177 256206.21285559254 255166.44338041963 289298.303310192 0.852026385572162 0.6935487989466731 0.9103397491720218 0.9963798190293444 1.0356691003994412 0.943324434359515 0.8876986080243089 0.8856125664203519 0.8820184579749316 1.0 18.14219833654584 -5.409569984798961 5.872237706908872 0.9441878867780269 0.774591226869272 0.5577211876011351 0.06114541594564548 0.169711095087617 7.597418948564426 0.01712485528808375 0.03620060802026144 3.894305474896003e-06 5.409569984798961 -0.16959665990875494 SSTFPQTDVLSSS(ph)LEAEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTFPQTDVLSSSLEAEHR 19 0 D4PHA4;Q86WP2-4;Q86WP2-3;Q86WP2;Q86WP2-2 D4PHA4 GPBP1 Vasculin 1 SSTFPQTDVLS(0.002)S(0.204)S(0.794)LEAEHR 186.35 3.6858000000000005e-11 8081900.0 24217.0 28470.0 34866.0 39732.0 57790.0 56977.0 49186.0 49127.0 51490.0 45217.0 True False 28316.459792447564 31296.31344832481 35697.33767004135 37505.944852882 46466.464348986134 53989.02581772402 44526.74600419768 47837.46830435912 52242.94384049028 53414.484162424946 0.53012699151679 0.5859143627252432 0.6683081982312405 0.7021680624834341 0.8699225514878888 1.0107562895028992 0.8336080878137647 0.8955898208975115 0.9780669917475531 1.0 15.704943383557374 -6.001408070796573 1.2015478724290063 0.9373263748009505 0.554799534716382 0.8908417606693249 0.05491906287515495 0.1546574827760912 0.4540642481017027 0.02162495297435655 0.04183060272343135 9.967630474378413e-07 6.001408070796573 -0.3825268400845685 SSTFPQTDVLSSS(ph)LEAEHR ddPTM_PC-9_Lapatinib_30min_R1 2 SSTFPQTDVLSSSLEAEHR 19 0 D4PHA4;Q86WP2-4;Q86WP2-3;Q86WP2;Q86WP2-2 D4PHA4 GPBP1 Vasculin 1 SSTFPQTDVLS(0.001)S(0.198)S(0.801)LEAEHR;SSTFPQTDVLS(0.003)S(0.221)S(0.776)LEAEHR 213.23 7.447499999999999e-28 45736000.0 164309.0 144124.0 186854.0 174934.0 182390.0 213987.0 175092.0 193609.0 251530.0 199448.0 True False 161965.92352941938 143790.28973295185 171491.5853972982 187799.2299227174 171662.17879253667 204835.27483806087 184157.40702826416 202604.78094440332 223200.04267167664 233922.32105224478 0.6923919136953396 0.61469247178356 0.7331133883499593 0.8028273192483152 0.7338426620441972 0.8756551060055208 0.7872588054011913 0.8661199155045708 0.9541630814351684 1.0 17.835670005793418 -6.096277216415634 0.20715888251819556 1.0454088270960793 0.46543765071525167 0.8303047980735156 0.04668587543775928 2.8656655225522796 0.20244668748043815 0.11820339318199337 0.4559768178536373 8.011665040319584e-07 6.096277216415634 -0.5799711763808276 SSTGPEPPAPT(ph)PLLAER ddPTM_PC-9_AZD4547_30min_R2 2 SSTGPEPPAPTPLLAER 17 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SSTGPEPPAPT(1)PLLAER;SSTGPEPPAPT(1)PLLAER 232.73 5.71e-31 31227000.0 69606.0 64888.0 80860.0 119976.0 100880.0 99411.0 72249.0 102038.0 74068.0 92007.0 True False 91739.26010525879 85861.77704600064 79787.7435670146 92317.3868107222 86874.5533155528 93194.81445481334 78679.02103514117 86270.3716999762 77983.08326718099 88785.8629347514 1.033264272857018 0.9670658617025588 0.8986536924876259 1.0397757453634944 0.9784728158738151 1.049658260609598 0.8861660903488909 0.9716678854985749 0.878327705442145 1.0 16.438042359079887 -7.269873637093308 24.99545162053393 0.9316794148443801 0.9902109125326117 0.23517467379522294 0.052995380965333315 1000.387934570052 2964701.4220389323 0.021427806857758205 0.014714780412482559 5.371880745985289e-08 7.269873637093308 0.058531497688231626 SSTGPEPPAPT(ph)PLLAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSTGPEPPAPTPLLAER 17 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SSTGPEPPAPT(1)PLLAER;SSTGPEPPAPT(1)PLLAER;SST(0.001)GPEPPAPT(0.999)PLLAER;SSTGPEPPAPT(1)PLLAER 143.55 9.9022e-05 29035600.0 80714.7 67784.0 77941.9 75671.1 88009.1 67607.3 69553.8 63733.6 70078.1 62246.0 True False 94378.10452200816 74513.14755115042 79800.33049230184 71431.49359601611 70764.34863361048 64061.854172150335 62965.16053809543 62060.66053133111 71102.85963775999 73530.70706093509 1.2835196109809848 1.0133609552999563 1.0852653766292646 0.9714511997935861 0.9623781881353035 0.8712258692013135 0.8563110985171954 0.8440101151196775 0.9669818566933793 1.0 16.16605923729462 -1.5228787452804269 0.5146608150153542 0.8990717930400923 13.61007234903941 0.7428322181369149 0.062232574760820586 55.5816148681284 0.5666777575348224 0.03311662590014781 769.2738553329684 0.02999999999999383 1.5228787452804269 12.711000555999318 SSTGPEPPAPT(ph)PLLAER ddPTM_PC-9_Lapatinib_30min_R1 2 SSTGPEPPAPTPLLAER 17 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 SSTGPEPPAPT(1)PLLAER;SSTGPEPPAPT(1)PLLAER 143.43 9.1415e-05 27290000.0 84642.0 72890.0 86155.0 82219.0 85740.0 78938.0 59719.0 64216.0 86181.0 60579.0 True False 83434.98955855842 72721.22768334816 79071.66846791755 88265.6595345438 80696.94177132567 75562.00575346555 62810.95761268885 67199.70979203367 76474.38825383753 71049.99943355647 1.174313725879533 1.023521861549831 1.1129017466335474 1.2423034516289733 1.1357768109032949 1.0635046636999421 0.8840388193307096 0.9458087308625039 1.0763460783043886 1.0 16.11654701751567 -7.0032986072935195 4.535596039820198 0.9712587827571835 1.1340946762239494 0.553099519693065 0.06808025459973949 0.15787036286551032 8.360167531766118 0.027024943148640464 0.02226980310742874 9.924334476022446e-08 7.0032986072935195 0.16283589346676597 SSTIYSNS(ph)AESFLPGICK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTIYSNSAESFLPGICK 18 0 Q15058 Q15058 KIF14 Kinesin-like protein KIF14 1 SSTIYS(0.093)NS(0.906)AES(0.001)FLPGICK 173.34 3.4114e-25 0.0 10820.0 10443.0 12227.0 12423.0 16281.0 12060.0 14914.0 11969.0 11607.0 9696.7 True False 12651.612295258812 11479.712024617354 12518.538051155723 11726.979585909425 13090.854924136418 11427.552369583367 13501.237951990479 11654.826432203772 11776.730416713353 11454.63495096503 1.104497205665462 1.002189251229714 1.0928797036959315 1.0237759331580838 1.1428434847706377 0.9976356661301213 1.1786702945826333 1.017476897526261 1.0281192257219152 1.0 13.48364386151597 -7.924159086079754 24.999999993464986 1.0169193102625012 1.0743909830370804 0.20724770644659718 0.05557536967405401 56.79624168897473 18719.91328715769 0.02811133881468801 0.013504242570596976 1.1908057249899581e-08 7.924159086079754 0.05747167277457921 SSTLGQEERPPEPPPGPPS(ph)KSSPQAR ddPTM_PC-9_AZD4547_30min_R2 1 SSTLGQEERPPEPPPGPPSKSSPQAR 26 2 G5E9Y3;Q8WWN8;Q8WWN8-2 G5E9Y3 ARAP3 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 1 SSTLGQEERPPEPPPGPPS(0.333)KS(0.333)S(0.333)PQAR 57.04600000000001 0.011343 5333700.0 6728.6 6704.2 7828.9 12810.0 9328.1 7666.0 4411.6 8803.8 7828.2 6608.6 True False 8868.154836425663 8871.201542223489 7725.08367068761 9856.852412527098 8033.054329726471 7186.643808135894 4804.223853598375 7443.375001198092 8241.982670412952 6377.234925501291 1.390595601388884 1.3910733485368905 1.2113531586858342 1.545631065449935 1.2596453515619894 1.126921603499024 0.7533396385300535 1.167179049878423 1.2924069391665196 1.0 12.638715313046877 -6.695429381517515 3.2573599707797496 1.0546186671928173 1.3744463141083707 0.49990492996172264 0.14977016571924065 0.21635365283846764 4.634987978093881 0.05476406862192094 0.052993728958487085 2.016371816279331e-07 6.695429381517515 0.31982764691555343 SSTLGQEERPPEPPPGPPSKS(ph)SPQAR ddPTM_PC-9_Lapatinib_30min_R1 1 SSTLGQEERPPEPPPGPPSKSSPQAR 26 2 G5E9Y3;Q8WWN8;Q8WWN8-2 G5E9Y3 ARAP3 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 1 SSTLGQEERPPEPPPGPPS(0.041)KS(0.48)S(0.48)PQAR 60.347 0.028165 0.0 10754.0 5586.8 7572.9 7462.0 7515.9 7073.5 6048.3 6884.6 8272.0 5455.3 True False 10600.645987957929 5573.864107851972 6950.2853942393585 8010.780372502283 7073.829538827931 6770.982894133858 6361.451379440809 7204.483649467961 7340.320251978326 6398.241336269668 1.6568062113984539 0.8711556527659321 1.0862805932061865 1.2520284796216776 1.1055896717631704 1.0582568768938478 0.994249989193076 1.1260099878740042 1.1472402909168653 1.0 12.643459695382777 -4.74830681941155 24.999993186126375 1.0795265785820876 1.6568075964492945 0.7648557485901603 0.09731145905643707 321.4515167068062 611900.0137769985 0.024806678839229487 0.45940991128847936 1.7852259067573185e-05 4.74830681941155 0.577281017867207 SSTPEEVK ddPTM_PC-9_Lapatinib_30min_R1 1 SSTPEEVK 8 0 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 0 95.815 0.029077 11422000.0 54567.0 52137.0 52231.0 44814.0 52379.0 43031.0 60307.0 48739.0 49548.0 54409.0 False True 53788.86457363775 52016.27997978774 47936.76879749055 48109.77105512157 49298.170201076144 41190.664440160304 63429.40137558277 51003.59187046726 43967.38247642917 63813.52315456467 0.8429069876514123 0.8151294178476486 0.7512007867263722 0.7539118462178218 0.7725348447173109 0.645484881635373 0.9939805583520047 0.7992599271933304 0.6889978848203451 1.0 15.961574567186242 -10.62588966366115 5.558844831799099 1.000002209665006 0.7859330490639357 0.34500100287695223 0.08893432553830853 2.4335990148630634e-06 3.9256875415220214e-07 0.08604311521705221 0.020868305247901408 2.3665208565880626e-11 10.62588966366115 -0.2140691606010704 SSTPGS(ph)PTHVSSGSNASR ddPTM_PC-9_AZD4547_30min_R2 1 SSTPGSPTHVSSGSNASR 18 0 Q14CZ0 Q14CZ0 C16orf72 UPF0472 protein C16orf72 1 SSTPGS(0.574)PT(0.03)HVS(0.388)S(0.007)GSNASR 182.49 2.1204000000000002e-09 1291400.0 0.0 0.0 2716.4 7191.0 4252.7 3282.7 628.11 4578.7 1244.9 2188.6 True False 0.0 0.0 2680.3787611357707 5533.226049842497 3662.286011945387 3077.4322500610115 684.0105731896991 3871.1671230588727 1310.7028724862794 2111.9777801579953 0.0 0.0 1.2691320838305664 2.619926261453641 1.7340551810499705 1.4571328727856176 0.32387204998839 1.8329582628323267 0.6206044802176975 1.0 11.044378941032459 -5.280969760967182 5.531701700460353 1.4173818386571715 4.982869115458191e-13 0.4397105752925192 0.6111258725773457 0.146891343469675 15.596489686212628 0.16676991098047397 0.38354917478093314 5.2363689507802535e-06 5.280969760967182 -1.4173818386566732 SSTPGSPT(ph)HVSSGSNASR ddPTM_PC-9_AZD4547_30min_R2 1 SSTPGSPTHVSSGSNASR 18 0 Q14CZ0 Q14CZ0 C16orf72 UPF0472 protein C16orf72 1 SST(0.025)PGS(0.18)PT(0.257)HVS(0.257)S(0.257)GS(0.024)NAS(0.001)R 166.36 3.1575e-07 1114900.0 415.02 0.0 3293.0 8597.9 4223.1 2662.4 426.91 3835.7 840.03 3174.0 True False 546.9877270477332 0.0 3249.3326683920236 6615.786991230818 3636.795461012196 2495.9197071198796 464.9041629657452 3242.9807006174037 884.4322708447659 3062.8792260904115 0.17858612327523324 0.0 1.0608752185568902 2.1599895075443403 1.1873780167474495 0.81489328271875 0.15178664539090184 1.0588013634337392 0.2887584542383973 1.0 11.580672765096947 -5.261905630248534 24.99829480291305 0.9835820259000823 0.08929299518109904 0.31563649445418074 0.5154061443406911 50.251073567518155 2694424.661553564 0.14642993312054386 0.33824527979175945 5.471348393052159e-06 5.261905630248534 -0.8942890307189832 SSTPLHS(ph)PSPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTPLHSPSPIR 12 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 SST(0.008)PLHS(0.749)PS(0.241)PIR 66.568 0.022073 24292000.0 22031.0 31577.0 31770.0 39925.0 49960.0 52016.0 53067.0 50665.0 44707.0 34945.0 True False 25760.41316791561 34711.75587487714 32527.51728839594 37688.131688596455 40170.696640860806 49288.18939106532 48040.10958819091 49335.09743400485 45360.75529766556 41280.25187553219 0.6240372090167511 0.8408804282381728 0.7879679946351246 0.9129821155702572 0.973121403473581 1.1939895507342977 1.1637552438643297 1.1951258820503217 1.098848801466543 1.0 15.333164153083693 -6.124525941407256 1.1429654500689295 1.1464788799827559 0.727772440044965 0.8187721360608218 0.07707935063177675 0.18988690373144762 0.5091831756087781 0.030341467120580685 0.05220291645193346 7.507132109556989e-07 6.124525941407256 -0.4187064399377909 SSTPLHS(ph)PSPIR ddPTM_PC-9_Lapatinib_30min_R1 2 SSTPLHSPSPIR 12 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 SST(0.003)PLHS(0.939)PS(0.057)PIR;S(0.068)S(0.068)T(0.319)PLHS(0.518)PS(0.026)PIR 78.191 0.009489000000000001 58306000.0 107254.0 82878.0 137953.0 102332.0 137233.0 157014.0 119882.0 116556.0 210462.0 108613.0 True False 105724.5382920255 82686.10108300921 126611.0368539796 109857.83664954461 129161.22475045887 150298.87723751093 126088.90337286908 121971.61726859753 186757.5532968885 127386.61233227463 0.8299501521891023 0.6490956904272733 0.9939116406026088 0.862397034022633 1.0139309177447577 1.1798639942278397 0.9898128309117711 0.957491647163419 1.4660689210397637 1.0 16.958854140282845 -5.8724828674689125 0.6826991656724676 1.1317061685696632 0.7030938293907086 0.4460967892338771 0.15295459663534205 0.9788046583117884 0.8249822006502118 0.08425689451901056 0.2671366060223202 1.3412728463826977e-06 5.8724828674689125 -0.4286123391789546 SSTPLPTIS(ph)SSAENTR ddPTM_PC-9_Lapatinib_30min_R1 1 SSTPLPTISSSAENTR 16 0 P42166;G5E972;P42167;H0YJH7;P42167-2;P42167-3 P42166;G5E972 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 SSTPLPT(0.018)IS(0.426)S(0.426)S(0.13)AENTR 130.47 1.3679e-05 9598600.0 54240.0 79349.0 55517.0 42346.0 51212.0 56242.0 54892.0 52812.0 65735.0 36766.0 True False 53466.527653602185 79165.27226568807 50952.60656181736 45460.26610211496 48199.810846665896 53836.66076650545 57734.0391713812 55265.83831968475 58331.232079762565 43120.95411238441 1.239919866203668 1.835888697160151 1.1816205742809314 1.0542500053137436 1.1177816409406125 1.2485034683182825 1.3388859397895345 1.281646926820024 1.3527351905928662 1.0 15.396101479670872 -5.302250375280499 24.906679554476884 1.2059763371410055 1.5379045274147427 0.38337773312225454 0.17266900090471596 421.9185739137493 257493.34425805105 0.04396222204985845 0.09151615432366282 4.9859695826006355e-06 5.302250375280499 0.3319281902737372 SSTPLPTISS(ph)SAENTR ddPTM_PC-9_Lapatinib_30min_R1 2 SSTPLPTISSSAENTR 16 0 P42166;G5E972;P42167;H0YJH7;P42167-2;P42167-3 P42166;G5E972 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin 1 SSTPLPT(0.028)IS(0.093)S(0.435)S(0.435)AENT(0.008)R;SSTPLPT(0.001)IS(0.138)S(0.43)S(0.43)AENT(0.002)R 109.1 0.00072072 8769100.0 68671.0 90656.0 51430.1 44567.2 54976.0 51368.0 52814.1 46990.8 54603.1 32427.7 True False 67691.73894728102 90446.09160188823 47201.715703927155 47844.820559820895 51742.41976697458 49171.110384656546 55548.55567662399 49174.16411634937 48453.12388186626 38032.78473780578 1.7798259952286195 2.378108577255506 1.241079664014378 1.2579888874732237 1.360468872413147 1.2928611650090118 1.4605440032742854 1.292941457096848 1.2739830705507698 1.0 15.214955955655437 -5.272754970643913 24.990561786058738 1.2930144626203068 2.0789672847456524 0.7746635509836681 0.17370408694679595 260.4093540192998 575116.2759042449 0.04179877174265464 0.08825360529686237 5.336358884406847e-06 5.272754970643913 0.7859528221253456 SSTPLSEAK ddPTM_PC-9_Lapatinib_30min_R1 2 SSTPLSEAK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 0 ; 95.815 0.012799 0.0 26630.0 23375.0 26065.0 22564.0 30532.0 24362.0 21028.0 22799.7 23486.0 22183.1 False True 26250.251316656115 23320.876623655728 23922.036313809615 24223.431831297443 28736.167788221577 23320.094050595755 22116.726949205793 23859.05729639699 20840.759361455886 26017.419277877227 1.008949082777663 0.8963562594190737 0.9194623055542895 0.9310466796333938 1.104497240149261 0.8963261806071972 0.8500738183518372 0.9170416574208224 0.8010309992266187 1.0 14.66719024476972 -6.970604285301591 24.999828742416433 0.8834199214778646 0.9664311735469916 0.2269861759441315 0.07201380065957624 305.55060887249374 259857.21809697046 0.025083665391094984 0.022121433158150856 1.0700294104120382e-07 6.970604285301591 0.08301125206912696 SSTPS(ph)HGQTTATEPTPAQK ddPTM_PC-9_Lapatinib_30min_R1 1 SSTPSHGQTTATEPTPAQK 19 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 S(0.001)S(0.001)T(0.027)PS(0.958)HGQT(0.012)T(0.001)ATEPTPAQK 103.87 0.00015307 9237300.0 26185.0 16980.0 35846.0 20586.0 29129.0 32486.0 26255.0 24486.0 35196.0 20153.0 True False 25811.597098259095 16940.683853248083 32898.88024956148 22099.963112882877 27415.68948981743 31096.649508564708 27614.355433298362 25623.708950537784 31231.85584968922 23636.419197815467 1.0920265410018055 0.7167195551690749 1.391872431023819 0.9349962415172179 1.1598918288076077 1.3156243866007729 1.1682969066587947 1.084077445745504 1.3213446414326473 1.0 14.528723870359032 -5.257103477019221 24.990556463863815 1.1711142294456354 0.9043730688031951 0.3097732575570037 0.1597984174189191 408.21218663774 2352763.5199901937 0.03849893234268281 0.09476876346939471 5.5321828115571086e-06 5.257103477019221 -0.26674116064244024 SSTQFGS(ph)YK ddPTM_PC-9_Lapatinib_30min_R1 1 SSTQFGSYK 9 0 Q4ADV7-2;Q4ADV7-3;Q4ADV7 Q4ADV7-2 RIC1 RAB6A-GEF complex partner protein 1 1 SSTQFGS(0.619)Y(0.381)K 84.568 0.013106999999999999 19325000.0 16016.0 8620.8 17048.0 11091.0 11081.0 10764.0 12267.0 13352.0 13491.0 11182.0 True False 15787.608903025304 8600.839067260373 15646.37924718306 11906.669138491403 10429.237366084217 10303.64881210954 12902.125237108028 13972.382663872437 11971.501513471907 13114.793800921565 1.2038015345628936 0.6558119935256626 1.193032805905313 0.9078807733641021 0.795226941757282 0.7856508435066293 0.9837840711000281 1.065390952840647 0.9128242269909482 1.0 13.678907504367254 -10.067518303039858 10.062003461431672 1.0000018531520225 0.9381467866314436 0.008320689584556007 0.1669624093032585 0.0 0.0 0.15442880138636791 0.03745448586785447 8.560156347744008e-11 10.067518303039858 -0.06185506652057893 SSTQFHVFES(ph)TR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSTQFHVFESTR 12 0 Q9BXC9;H3BRL0;H3BNS7 Q9BXC9 BBS2 Bardet-Biedl syndrome 2 protein 1 SSTQFHVFES(0.5)T(0.5)R;SSTQFHVFES(0.5)T(0.5)R 74.376 0.020903 764550.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SSTS(ph)PCGTSK ddPTM_PC-9_Lapatinib_30min_R1 1 SSTSPCGTSK 10 0 O75376-2;O75376;A0A088AWL3;O75376-3;H0Y459 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 S(0.09)S(0.026)T(0.026)S(0.857)PCGTSK 121.29 0.00063498 9510000.0 28998.0 84259.0 39547.0 51447.0 89096.0 39783.0 150650.0 132150.0 79500.0 66580.0 True False 28584.483202418076 84063.90346235734 36295.59831583464 55230.58400216092 83855.54844947552 38081.57382870251 158449.91986388894 138290.17143729376 70545.87282788656 78088.2642877265 0.36605350961694805 1.0765241644072507 0.4648022164009015 0.7072840522957016 1.0738559656096172 0.4876734574146242 2.0291130979689767 1.7709469239544804 0.903411971969962 1.0 16.252818124765618 -7.246809572606156 24.998915675552144 1.490113604219135 0.7205020987770767 0.46446297402521197 0.3808975053853071 671.2715837643976 1147047.6441129472 0.14251118693207995 0.1098890799422672 5.6648762540883506e-08 7.246809572606156 -0.7696115054420583 SSTSGDT(ph)EEEEEEEVVPFSSDEQKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTSGDTEEEEEEEVVPFSSDEQKR 25 1 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;O15231-3;O15231-2;O15231-4;O15231-5 O15231-7;O15231-3;O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 S(0.052)S(0.052)T(0.06)S(0.192)GDT(0.643)EEEEEEEVVPFSSDEQKR 59.673 0.0030932 34440000.0 12140.0 12484.0 10258.0 11513.0 14251.0 9437.2 11331.0 12067.0 9605.7 8506.5 True False 14195.062224070429 13723.329016118269 10502.589623681633 10867.963935649612 11458.61885165948 8942.296618758885 10257.645650664084 11750.254036043347 9746.165190300977 10048.661112583057 1.4126321969695244 1.3656873151920457 1.0451730341000516 1.0815335310731709 1.1403129952617126 0.88989931281106 1.020797252065684 1.1693352879946897 0.9698968928404511 1.0 13.2947156685243 -5.238466337046482 4.506431140725954 1.0435563175218974 1.3999534140790366 0.7700422476696847 0.07650756932083427 0.08969700244094367 4.69501573124256 0.020241404355964224 0.0538984938076629 5.774756321636121e-06 5.238466337046482 0.35639709655713925 SSTTVSSFANS(ph)KPGSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTTVSSFANSKPGSAK 17 1 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 S(0.006)S(0.006)T(0.038)T(0.243)VS(0.032)S(0.005)FANS(0.657)KPGS(0.014)AK 74.047 0.004654999999999999 14640000.0 56490.0 45285.0 40128.0 69375.0 52187.0 47940.0 53526.0 51926.0 39856.0 38887.0 True False 66052.64127164235 49780.59552186119 41084.80370628748 65488.1436667846 41961.33197751409 45425.94200645324 48455.62978531865 50562.99752014479 40438.8185998559 45936.90527067739 1.4378992420676913 1.0836732520080608 0.8943746528896643 1.4256106997392188 0.9134557874602625 0.9888768461607641 1.0548300870465694 1.1007053527487047 0.8803122100101278 1.0 15.487366046429926 -4.769578926090587 4.710902915606243 1.0416364064319257 1.464678462545516 0.39812637849693944 0.14828753498175543 0.18489052242937457 9.734488678115637 0.03592227202598078 0.2596241286207921 1.6998909975113686e-05 4.769578926090587 0.42304205611359036 SSTTVSSFANSKPGS(ph)AK ddPTM_PC-9_AZD4547_30min_R2 2 SSTTVSSFANSKPGSAK 17 1 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 S(0.021)S(0.021)T(0.038)T(0.033)VS(0.169)S(0.041)FANS(0.037)KPGS(0.639)AK;SSTTVSSFANS(0.013)KPGS(0.987)AK 70.538 0.006882300000000001 37572000.0 165842.0 179871.0 206561.0 271737.0 251013.0 204699.0 212160.0 261561.0 224771.0 245819.0 True False 218576.30627210782 238010.78318088403 203821.86617544008 209092.23294479903 216164.1777497701 191899.13917057283 231041.8289916203 221142.75752383942 236651.93618090905 237212.9516314799 0.921434958626016 1.003363355769223 0.85923582491434 0.8814536959585261 0.911266337959447 0.8089741215677635 0.9739848832139373 0.9322541454962114 0.9976349712496204 1.0 17.855823256430334 -7.926472716286296 1.5917378243861569 0.9973596436391261 0.9027392213130049 0.34133981643608 0.05082680209287946 0.49122705868362937 2.2623886913377134 0.04482396851118775 0.015584600368748997 1.184478777255849e-08 7.926472716286296 -0.09462042232612122 SSTTVSSFANSKPGS(ph)AK ddPTM_PC-9_Lapatinib_30min_R1 2 SSTTVSSFANSKPGSAK 17 1 A0A669KAX4;Q13620-1;A0A669KAU9;Q13620;K4DI93 A0A669KAX4;K4DI93 CUL4B Cullin-4B 1 SSTTVSSFANS(0.01)KPGS(0.99)AK;SSTTVS(0.001)S(0.001)FANS(0.042)KPGS(0.956)AK 72.564 0.0055894 33455000.0 199151.0 181807.0 160196.0 153902.0 135233.0 111885.0 96529.0 98617.0 112532.0 80699.0 True False 196311.07022017927 181386.0370616891 147025.30325444296 165220.46648202147 127278.86081830744 107099.93936667385 101526.7992999756 103199.10583905855 99857.46114550595 94647.71462534167 2.0741237228734684 1.9164333526667476 1.553395175323941 1.7456360899577825 1.3447642272413503 1.1315639240801925 1.0726809379588766 1.0903496851198906 1.0550435532520441 1.0 16.530280050417765 -5.853007507201909 0.5663639550733373 0.9912707217307202 2.2093126084184296 0.9401361105929245 0.09223933477346573 0.3283317320648483 0.17690564326163308 0.06525254292507603 0.2300632268887086 1.4027894557742374e-06 5.853007507201909 1.2180418866877094 up SSTVAS(ph)LDTDSTK ddPTM_PC-9_AZD4547_30min_R2 4 SSTVASLDTDSTK 13 0 C9IZZ8;C9J6Y2;C9J0J6;C9JZ07;G3V1A3;C9J5T5;C9JBU8;A8MPU2;O14713-2;O14713 C9IZZ8 ITGB1BP1 Integrin beta-1-binding protein 1 1 SST(0.002)VAS(0.99)LDT(0.007)DSTK;SST(0.003)VAS(0.995)LDT(0.002)DS(0.001)TK;SSTVAS(0.706)LDT(0.292)DS(0.001)TK;SSTVAS(0.992)LDT(0.008)DSTK 169.79 6.977e-05 36483600.0 158814.0 164776.0 208048.0 290234.0 276903.0 271416.0 231935.0 263670.0 227279.0 256925.0 True False 209313.54846358913 218036.6196296977 205289.14758385182 223325.03537060058 238459.7981436997 254444.31461375082 252576.76568236892 222925.86003383773 239292.50394072544 247930.13395188397 0.8442440825051577 0.8794276684092474 0.8280120867586531 0.9007579345475669 0.961802401115057 1.026274259437665 1.0187416981406008 0.8991479030019851 0.9651610319670345 1.0 17.919574104719338 -6.141239072375019 2.7705521429385143 0.9788930011961502 0.8540131781710442 0.728569288568265 0.035471770798103146 0.15880494207562387 2.361108512577045 0.01200968862437044 0.016348769127585743 7.223720395292322e-07 6.141239072375019 -0.12487982302510603 SSTVAS(ph)LDTDSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSTVASLDTDSTK 13 0 C9IZZ8;C9J6Y2;C9J0J6;C9JZ07;G3V1A3;C9J5T5;C9JBU8;A8MPU2;O14713-2;O14713 C9IZZ8 ITGB1BP1 Integrin beta-1-binding protein 1 1 S(0.001)S(0.004)T(0.099)VAS(0.887)LDT(0.008)DS(0.001)TK;SSTVAS(1)LDTDSTK 201.48 2.2855999999999998e-07 11985100.0 33440.0 39479.0 33332.0 49668.0 61187.0 53883.0 54503.0 53896.0 49897.0 46754.0 True False 39100.73152989415 43398.21421237846 34126.76129231392 46885.26298582863 49197.846584554645 51057.280624399675 49340.08127245121 52481.287107532306 50626.64922915022 55230.13009553966 0.7079601562092263 0.7857706316698186 0.6179011570908823 0.8489073428710798 0.8907791181996115 0.9244461408307098 0.8933544278657398 0.9502292863831341 0.916649103334971 1.0 15.753167905255888 -5.9633483484496566 4.4979605227454265 0.9213698015404418 0.7121248811764325 0.8097195426800254 0.04859697373652823 0.08431076818508258 3.9240493965116565 0.0137094976559549 0.020300910854523575 1.088057010582543e-06 5.9633483484496566 -0.20924492036400932 SSTVAS(ph)LDTDSTK ddPTM_PC-9_Lapatinib_30min_R1 1 SSTVASLDTDSTK 13 0 C9IZZ8;C9J6Y2;C9J0J6;C9JZ07;G3V1A3;C9J5T5;C9JBU8;A8MPU2;O14713-2;O14713 C9IZZ8 ITGB1BP1 Integrin beta-1-binding protein 1 1 SSTVAS(0.847)LDT(0.152)DSTK 128.35 0.00010593 8653800.0 126910.0 118790.0 125400.0 107900.0 132770.0 144890.0 129300.0 113710.0 139530.0 124120.0 True False 125100.24012755614 118514.94905343572 115090.09605799816 115835.32594384847 124960.72963586335 138693.39245508643 135994.5213302412 118993.38171876375 123814.66208396218 145573.97662049573 0.8593585408035282 0.814121808064627 0.7905952611161571 0.7957145132184272 0.8584001930621837 0.95273479281708 0.9341952764316681 0.8174083341075012 0.8505274428735362 1.0 17.151392951154072 -6.517106614380175 6.50705852843222 0.901678959243213 0.8145524511369951 0.43648804082730586 0.050986296482094774 0.15981202302087646 32.933336903865666 0.017192181783378016 0.018208044369150127 3.0401386144392257e-07 6.517106614380175 -0.0871265081062178 SSTVASLDT(ph)DSTK ddPTM_PC-9_Lapatinib_30min_R1 2 SSTVASLDTDSTK 13 0 C9IZZ8;C9J6Y2;C9J0J6;C9JZ07;G3V1A3;C9J5T5;C9JBU8;A8MPU2;O14713-2;O14713 C9IZZ8 ITGB1BP1 Integrin beta-1-binding protein 1 1 S(0.001)STVAS(0.241)LDT(0.747)DS(0.005)T(0.006)K;S(0.02)S(0.116)T(0.012)VAS(0.297)LDT(0.538)DS(0.014)T(0.004)K 165.51 0.00076327 21525900.0 112425.0 98717.0 104116.0 86384.0 105532.0 113370.0 113645.0 102394.0 117736.0 98948.0 True False 110821.79888377977 98488.42685165422 95555.98437938257 92736.96752857624 99324.81524389495 108521.42937837786 119528.98203074448 107151.59904767487 104475.33186495655 116051.02996007785 0.9549402441486563 0.8486648234447789 0.8233962629392804 0.7991050795540395 0.8558718977165751 0.9351181925374534 1.0299691615995399 0.9233145029780052 0.9002533790600272 1.0 16.82439980118386 -6.813249715646359 4.254336073939616 0.9598138571185583 0.8504090182518814 0.501760209955592 0.05081166407225525 0.18605636194997294 6.96711034827443 0.019034698515850237 0.017152453380117404 1.537270468641005e-07 6.813249715646359 -0.10940483886667685 SSTVPSSNT(ph)ASGGMTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSTVPSSNTASGGMTR 16 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;A2SY06;H0YKP9 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 S(0.074)S(0.057)T(0.097)VPS(0.016)S(0.016)NT(0.505)AS(0.233)GGMT(0.001)R 80.737 0.039605 0.0 8646.4 13289.0 5447.4 6542.3 9657.4 7654.0 3652.8 6991.2 4158.8 4163.7 True False 10110.06474581569 14608.244096058597 5577.286675379543 6175.756141422782 7765.101796225971 7252.610765903077 3306.780340018162 6807.688407788701 4219.614582323385 4918.545850168937 2.0554987294605453 2.9700331238259876 1.1339299958315892 1.255606093660927 1.578739333284707 1.4745436937736325 0.6723085319830014 1.384085584473077 0.8578987999427623 1.0 12.264016135828873 -5.272265975681199 24.929006830646806 1.1941649266546601 2.51276592180302 0.7216828357821007 0.333358476221388 299.2872633440371 689130.9488549585 0.0849596439757935 0.17970390441057907 5.342370755001305e-06 5.272265975681199 1.31860099514836 SSVAS(ph)PRR ddPTM_PC-9_Lapatinib_30min_R1 1 SSVASPRR 8 1 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 SSVAS(1)PRR 60.398 0.032072 1824600.0 5685.7 2979.8 5033.8 2913.2 4252.1 3637.1 3714.6 3874.0 5178.6 3858.1 True False 5604.620875370319 2972.900456178365 4619.940395029921 3127.446446150313 4001.9998379502476 3481.549711494205 3906.923812322611 4054.000182732309 4595.331534924442 4524.967444404894 1.2385991599343795 0.656999302802575 1.0209886483807658 0.6911533584661231 0.884426216789406 0.7694087867525166 0.8634147892386514 0.8959180883710148 1.0155501871304187 1.0 12.143691697197252 -8.164555463473237 3.3211347838974783 1.0099447428220425 0.8621497997016973 0.09546631103270709 0.15737965286919187 0.5291588696103761 10.433549166274862 0.11879649207963976 0.03797857841187869 6.846120461371592e-09 8.164555463473237 -0.14779494312034525 SSVKT(ph)PESIVPIAPELQPSTSR ddPTM_PC-9_AZD4547_30min_R2 1 SSVKTPESIVPIAPELQPSTSR 22 1 Q14676;Q14676-3;Q14676-2 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 S(0.007)S(0.007)VKT(0.982)PES(0.003)IVPIAPELQPSTSR 100.71 6.5045e-05 15169000.0 44178.0 35917.0 40817.0 53400.0 48759.0 46147.0 36783.0 43531.0 34298.0 45111.0 True False 58225.68504051557 47526.46785478374 40275.73991064598 41089.45502177573 41989.6544916042 43261.42079494485 40056.61574188707 36804.284192866035 36110.92225924523 43531.67762071976 1.3375474648099 1.0917674312685477 0.9252053243056257 0.9438978065531385 0.9645769882210649 0.9937917204080763 0.9201716527189693 0.845459816952892 0.8295320610859601 1.0 15.409777999226279 -4.77566859955019 1.6884745455111931 0.9234832111024122 1.49220409614045 0.8503423384908468 0.05325665254327156 0.3773860296355449 1.054761998322117 0.01618546790943318 0.35477026416167196 1.6762214754167608e-05 4.77566859955019 0.5687208850380377 SSVKT(ph)PESIVPIAPELQPSTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSVKTPESIVPIAPELQPSTSR 22 1 Q14676;Q14676-3;Q14676-2 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 S(0.015)S(0.015)VKT(0.778)PES(0.188)IVPIAPELQPS(0.001)T(0.001)S(0.001)R;S(0.144)S(0.144)VKT(0.678)PES(0.034)IVPIAPELQPSTSR 49.106 0.031729 12304200.0 48837.0 45310.0 36091.0 46990.0 51940.0 42853.0 52589.0 50482.0 45675.0 36771.0 True False 57104.13952528232 49808.07735664197 36951.5463158797 44357.302643635485 41762.72985440975 40605.71324160494 47607.389208611225 49156.9009901003 46342.91046638948 43437.29122092414 1.3146339912138614 1.1466662850433216 0.8506871694172264 1.0211802208851404 0.9614487616643154 0.934812279961988 1.0960027172614832 1.1316751023926872 1.0668922753651287 1.0 15.406646518051115 -4.958862581476289 4.248777433522336 1.0107164078273039 1.2978164994600112 0.6045995000133997 0.07766643022422592 0.15013194277049594 5.871841969053925 0.02133667034543213 0.09592198512962394 1.099353639513169e-05 4.958862581476289 0.28710009163270733 SSVKT(ph)PESIVPIAPELQPSTSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSVKTPESIVPIAPELQPSTSR 22 1 Q14676;Q14676-3;Q14676-2 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 S(0.102)S(0.102)VKT(0.777)PES(0.018)IVPIAPELQPSTSR 70.99 0.0012128 12096000.0 92449.0 75490.0 74779.0 54668.0 84939.0 74595.0 68033.0 75356.0 74697.0 61064.0 True False 91130.66030692957 75315.20754309182 68630.95927528746 58688.467087101955 79943.0550164991 71404.74573943808 71555.41585197438 78857.31486060281 66283.83726571874 71618.8310373345 1.2724399293730955 1.051611796118683 0.9582809197138462 0.8194558084382582 1.1162295426858506 0.9970107680508661 0.9991145459309848 1.1010695611534755 0.9255085053142705 1.0 16.12805135072948 -4.782929769800078 3.219183297196335 0.9926332256772072 1.312069349842548 0.5325940151483943 0.0793507191000209 0.26892227257210877 4.277722146005194 0.020418412322115886 0.2179820957028956 1.64842893908408e-05 4.782929769800078 0.31943612416534073 SSVKT(ph)PETVVPTALELQPSTSTDRPVTSEPTSQATR ddPTM_PC-9_Lapatinib_30min_R1 1 SSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATR 36 2 Q14676;Q14676-2;H0Y6Z8 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 S(0.044)S(0.044)VKT(0.826)PET(0.085)VVPT(0.001)ALELQPSTSTDRPVTSEPTSQATR 53.214 0.00070723 12128000.0 23089.0 22987.0 27393.0 17804.0 19350.0 21881.0 23654.0 18551.0 22167.0 21367.0 True False 22759.74662599596 22933.77501381707 25140.853280037878 19113.36555240292 18211.871043563715 20945.200637102287 24878.688380089116 19412.94718375506 19670.319031141637 25060.25748026213 0.9082008292980193 0.9151452267352036 1.0032160802752814 0.7626962958164704 0.7267232213359214 0.8357935130394837 0.9927546993355506 0.7746507472656661 0.7849208670994023 1.0 14.613113617177659 -5.75971442615374 24.999999677574568 0.8317725105677444 0.9394831572852814 0.21044278291819496 0.09007197466689848 70.64309202249774 1023804.5491298612 0.025446426588307456 0.04129330373538918 1.738943909507901e-06 5.75971442615374 0.10771064671753705 SSVLPS(ph)PSGR ddPTM_PC-9_AZD4547_30min_R2 1 SSVLPSPSGR 10 0 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-5;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 S(0.003)S(0.051)VLPS(0.72)PS(0.226)GR 70.72800000000001 0.035018 17543000.0 42761.0 45627.0 46792.0 65579.0 62225.0 69287.0 40953.0 73726.0 47934.0 55307.0 True False 56358.108515946566 60375.035465384586 46171.50750665035 50460.77473545008 53586.13283168381 64954.472936904705 44597.73766352664 62333.34075493883 50467.69338079948 53370.718764140634 1.0559743211442965 1.1312389426906144 0.8651093441460754 0.9454767689835626 1.0040361844946317 1.2170432484515668 0.835621829651871 1.167931446274996 0.945606402713623 1.0 15.703760820339397 SSVLPSPS(ph)GR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSVLPSPSGR 10 0 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-5;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 SSVLPS(0.335)PS(0.665)GR 70.72800000000001 0.035018 8517900.0 78698.0 105240.0 94049.0 83021.0 99256.0 81264.0 86545.0 61702.0 80648.0 71142.0 True False 92020.01704364861 115687.53169306986 96291.48484281852 78369.60252771356 79807.49931515759 77002.37278290401 78346.83106846035 60082.38787867294 81827.32442897386 84039.4814402379 1.094961742583881 1.3765855013674437 1.1457886601941167 0.9325331520928494 0.9496429291024392 0.9162642541727473 0.9322621906487405 0.7149304927755734 0.9736771696665318 1.0 16.35877963953869 -5.695405728219784 3.2190450325343702 0.9040584076882178 1.2417775047357544 0.6568933895086072 0.09671128829344787 0.1310831945134634 2.726809812557265 0.026647657698388196 0.04847576066308953 2.0164816384016704e-06 5.695405728219784 0.33771909704753666 SSVLPSPS(ph)GR ddPTM_PC-9_Lapatinib_30min_R1 1 SSVLPSPSGR 10 0 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-5;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 SSVLPS(0.129)PS(0.871)GR 76.165 0.023511 15659000.0 50946.0 61828.0 64064.0 54670.0 67915.0 85433.0 66849.0 67099.0 66129.0 56429.0 True False 50219.50069764785 61684.84106470097 58796.905214191414 58690.61417377372 63920.3732260274 81779.22974405004 70310.11412533085 70216.66449694263 58680.85565075855 66182.6774630838 0.7588012849081227 0.9320390686688116 0.8884032418753062 0.8867972167869893 0.9658172753993173 1.2356591313439362 1.0623643046860607 1.0609523094031508 0.8866497684910117 1.0 16.014166037542857 -6.524194581957398 24.99648091398302 1.0589816477932887 0.8794486844212588 0.4712334512683194 0.09047822888450387 40.21023586427367 763834.3506309317 0.030275150015868724 0.030505025270104024 2.990924278119251e-07 6.524194581957398 -0.17953296337202995 SSVMAEY(ph)GLYGAMVRHSIPLPESILK ddPTM_PC-9_Lapatinib_30min_R1 1 SSVMAEYGLYGAMVRHSIPLPESILK 26 1 P58304 P58304 VSX2 Visual system homeobox 2 1 S(0.017)S(0.017)VMAEY(0.857)GLY(0.108)GAMVRHS(0.001)IPLPES(0.001)ILK 50.215 0.027367000000000002 0.0 3577.4 2228.5 1948.7 2684.7 2032.2 3115.2 4746.5 2822.1 2799.0 3345.0 True False 3526.3856199851866 2223.3400451686316 1788.4854081995318 2882.1417938966583 1912.6699914589246 2981.9701578858817 4992.250545197131 2953.225068582565 2483.747145223326 3923.178793067666 0.8988592684627016 0.5667190210900704 0.45587659970017697 0.7346445181110429 0.4875306715153156 0.7600903030866403 1.2725014098308585 0.7527633137192146 0.6330955779053853 1.0 11.937807370266816 -7.0015682288820384 24.999999676709603 0.911459707538738 0.6217875342387943 0.3236447845485315 0.19466662721277198 72.87086573884949 1161693.5102313012 0.07010115057470714 0.060964611828028537 9.963955313034154e-08 7.0015682288820384 -0.28967217329994366 SSVQGASS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSVQGASSR 9 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 SSVQGAS(0.015)S(0.985)R 82.505 0.015677 7922400.0 11642.0 31301.0 31967.0 12581.0 78920.0 113970.0 25395.0 38490.0 76223.0 137710.0 True False 13612.760660018768 34408.356418897616 32729.214515522606 11876.12735815233 63456.19253196027 107993.21256728169 22989.401756121646 37479.67828352603 77337.61717525145 162675.7328882398 0.08368034013635518 0.21151499248223193 0.20119297411131365 0.0730049107343587 0.39007780327970265 0.6638557002320336 0.1413204129955612 0.23039501724129327 0.4754096742160266 1.0 17.311639527826046 -14.522878745273124 0.1622169814435965 3.7399613282823676 0.08454879472173246 0.6831646537761513 0.15771512859690384 84.20421196423769 0.7762339660612 74.10299270509756 0.6932044725876734 3.000000000049832e-15 14.522878745273124 -3.6554125335606353 SSVQGASS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 SSVQGASSR 9 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 SSVQGAS(0.092)S(0.908)R 69.21600000000001 0.040963 5721400.0 24692.0 30901.0 10750.0 27556.0 32506.0 13700.0 72630.0 56232.0 21981.0 28518.0 True False 24339.887552041786 30829.45063305176 9866.176496200018 29582.560164121256 30594.060989254893 13114.082936259818 76390.42601868066 58844.74400500861 19505.268309808474 33447.29830215359 0.7277086278288312 0.921732163672745 0.29497678428528734 0.884452905489724 0.9146945356505825 0.392081979769811 2.2839042283352993 1.7593272698267453 0.5831642404598214 1.0 15.029602061761485 -7.234082278068429 24.99932099618062 1.469876511173993 0.70103623303669 0.3624605089931726 0.4628728615256462 761.4470681045003 695822.5175912327 0.17643857601411 0.1366348696307898 5.833345797536361e-08 7.234082278068429 -0.768840278137303 SSVS(ph)SVGAR ddPTM_PC-9_AZD4547_30min_R2 2 SSVSSVGAR 9 0 Q9BZ67-2;Q9BZ67-3;Q9BZ67;Q8N4M4;E9PRA3;E9PRP1;E9PS62;Q9BZ68 Q9BZ67-2 FRMD8;FRMD8P1 FERM domain-containing protein 8;Putative FERM domain-containing protein FRMD8P1 1 SS(0.001)VS(0.5)S(0.5)VGAR;S(0.036)S(0.123)VS(0.421)S(0.421)VGAR 81.525 0.017105000000000002 5595900.0 24986.0 23694.0 36601.0 57116.0 43901.0 33506.0 30370.0 41216.0 31200.0 35734.0 True False 32931.02825891443 31352.62213857634 36115.64682533142 43948.78863340345 37806.10393642028 31410.86452327174 33072.87116551426 34847.01424945826 32849.168303937564 34482.96353658311 0.9549941443976465 0.9092206389196862 1.0473475340080962 1.2745072965314599 1.096370498907718 0.9109096580387538 0.9591075642447936 1.0105574079353397 0.9526202198105088 1.0 15.073596147474284 -6.754067429730091 24.999040881227405 0.9668280930370463 1.0599108800278818 0.18671083630197982 0.09362415409550941 337.22362280681654 1143558.9361543283 0.03550091064828585 0.03482661540144811 1.7617024985050435e-07 6.754067429730091 0.0930827869908355 SSVS(ph)SVGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SSVSSVGAR 9 0 Q9BZ67-2;Q9BZ67-3;Q9BZ67;Q8N4M4;E9PRA3;E9PRP1;E9PS62;Q9BZ68 Q9BZ67-2 FRMD8;FRMD8P1 FERM domain-containing protein 8;Putative FERM domain-containing protein FRMD8P1 1 S(0.026)S(0.017)VS(0.478)S(0.478)VGAR 76.17 0.024906 2974100.0 25211.0 24482.0 32965.0 29475.0 33839.0 26284.0 28612.0 23952.0 25140.0 23359.0 True False 29478.724360052667 26912.41116409862 33751.0106204587 27823.611309239324 27208.490865294036 24905.62076966246 25901.664227058587 23323.28537924175 25507.62493979268 27593.801790257727 1.0683096364945417 0.9753063883208845 1.2231373870480884 1.0083283021574336 0.9860363233782549 0.9025802591093353 0.938676896497946 0.8452363888283156 0.9243969038292653 1.0 14.75205662007872 -6.350706475386585 2.1338847850817966 0.9145261665060486 1.0782970336709516 0.5021829307737662 0.06935033447854763 0.25389480619929977 2.271080161753611 0.023692447614462795 0.028705480323339687 4.459575538452603e-07 6.350706475386585 0.16377086716490308 SSVS(ph)SVGAR ddPTM_PC-9_Lapatinib_30min_R1 2 SSVSSVGAR 9 0 Q9BZ67-2;Q9BZ67-3;Q9BZ67;Q8N4M4;E9PRA3;E9PRP1;E9PS62;Q9BZ68 Q9BZ67-2 FRMD8;FRMD8P1 FERM domain-containing protein 8;Putative FERM domain-containing protein FRMD8P1 1 SSVS(0.5)S(0.5)VGAR;SSVS(0.5)S(0.5)VGAR 96.665 0.0050318 5011900.0 44595.0 37961.0 44000.0 36474.0 41356.0 38971.0 34296.0 30866.0 44856.0 28627.0 True False 43959.067122278604 37873.10363681691 40382.48984491168 39156.41963369719 38923.521389024325 37304.301175838074 36071.67906838319 32300.14704187289 39803.84492537959 33575.13880692021 1.3092743227384112 1.1280103368928096 1.2027497511518375 1.1662325466135264 1.159295918711191 1.1110691571630746 1.074356811324587 0.9620257187206467 1.185515424203565 1.0 15.035105743629314 -1.5228787452803376 0.16678303849168336 0.9886149973023968 2.0725954647040683 0.5451152271244859 0.06442987278056195 46.38004841253086 0.4951578263470301 0.16985789521466876 12.478342182716244 0.029999999999999995 1.5228787452803376 1.0839804674016715 SSVSS(ph)VGAR ddPTM_PC-9_Lapatinib_30min_R1 1 SSVSSVGAR 9 0 Q9BZ67-2;Q9BZ67-3;Q9BZ67;Q8N4M4;E9PRA3;E9PRP1;E9PS62;Q9BZ68 Q9BZ67-2 FRMD8;FRMD8P1 FERM domain-containing protein 8;Putative FERM domain-containing protein FRMD8P1 1 SSVS(0.045)S(0.955)VGAR 106.88 0.0025396999999999998 3244600.0 18243.0 16290.0 19479.0 16153.0 17029.0 18066.0 18512.0 13932.0 18772.0 12094.0 True False 17982.85147464354 16252.281505854611 17877.51181111443 17340.945504828385 16027.38770030215 17293.359293902908 19470.460780088335 14579.331581266531 16657.699682076545 14184.431785757966 1.267787934423952 1.1457830494255605 1.260361506272288 1.2225336740129238 1.1299280748344551 1.2191788543314435 1.3726641344659194 1.0278403676279135 1.1743649610837348 1.0 13.792020738389546 -8.404399324834417 1.2084087857721835 1.0127735716545074 1.2189854967949842 0.3698377254470746 0.08470135867848465 0.4771590287912413 1.492907362854207 0.07774518233177873 0.02459796566642149 3.940947734018723e-09 8.404399324834417 0.20621192514047681 SSYLES(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 SSYLESPR 8 0 H0YIQ2;P49750-3;P49750-1;P49750;F8VU51 H0YIQ2 YLPM1 YLP motif-containing protein 1 1 SSYLES(1)PR;SS(0.002)YLES(0.998)PR;SSYLES(0.999)PR;SSYLES(1)PR 102.06 0.0043946 47897200.0 143587.0 186338.0 213432.0 221337.0 226536.0 259083.0 207853.0 297385.0 216160.0 220068.0 True False 189244.6792048648 246568.1144618064 210601.75222600883 170311.17427256142 195085.38669599537 242882.49905338846 226351.5143353852 251430.98147746356 227585.77630061377 212363.48630348593 0.8911356773189232 1.1610664279142557 0.9917041573005662 0.8019795551348781 0.9186390282612019 1.1437112061076649 1.065868329228261 1.183965218569386 1.0716803545755218 1.0 17.696176205468923 -6.761135266701979 24.999997129514952 1.1028443129056797 0.9582402518554437 0.3404456325429126 0.09690875851830923 10.105030905684904 830715.557298338 0.034792858006784076 0.0327654017610938 1.733264065889635e-07 6.761135266701979 -0.14460406105023604 SSYLES(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SSYLESPR 8 0 H0YIQ2;P49750-3;P49750-1;P49750;F8VU51 H0YIQ2 YLPM1 YLP motif-containing protein 1 1 S(0.002)S(0.007)YLES(0.991)PR;SSYLES(1)PR;SSYLES(1)PR;SSYLES(1)PR 103.26 0.0040284 37860700.0 125640.0 143409.0 189123.0 152885.0 192720.0 153049.0 161280.0 113032.0 128822.0 109091.0 True False 146908.37049688716 157645.69776293723 193632.40957297126 144319.3491098578 154957.89945209533 145022.84101263384 146002.39083391603 110065.02976730342 130705.77804271951 128868.3347361191 1.1399881188633985 1.2233082555597923 1.5025600351666542 1.1198976801040956 1.2024513218813548 1.1253566774925274 1.1329578451749374 0.85408902033755 1.0142582994524054 1.0 16.975538285604834 -7.168001242587953 1.078814301361176 0.9527825834349571 1.2596764921775485 0.52510306441657 0.11098799253411615 0.4022419201291367 0.9292568921563836 0.07565349586111798 0.04657920496464796 6.79201689306645e-08 7.168001242587953 0.30689390874259137 SSYLES(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 SSYLESPR 8 0 H0YIQ2;P49750-3;P49750-1;P49750;F8VU51 H0YIQ2 YLPM1 YLP motif-containing protein 1 1 SSYLES(1)PR;SSY(0.001)LES(0.999)PR;SSYLES(1)PR;SSYLES(1)PR 112.3 0.0037321999999999998 45117100.0 149770.0 200603.0 213319.0 156550.0 219146.0 236535.0 202910.0 196437.0 251595.0 197441.0 True False 147634.25233554558 200138.51607851186 195780.73525515286 168063.20923549111 206256.263137613 226418.9494400157 213415.68695374473 205564.1801485258 223257.72168719603 231568.41377640492 0.6375405433233934 0.8642738135770073 0.845455267678227 0.7257605063433548 0.8906925593780137 0.9777626652425863 0.9216096594236385 0.8877038832550455 0.9641112880911581 1.0 17.821078955761138 -6.44688622446253 4.816407194146816 0.9410752585697043 0.7815081998180207 0.6256922929172796 0.06595900733150334 0.16329551374077472 6.917807641637644 0.020793763108454565 0.023320598726696416 3.573664479855796e-07 6.44688622446253 -0.15956705875168364 SSYS(ph)SPTSLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 SSYSSPTSLSPR 12 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;A0A087WXJ0;C9J760;Q96JY6-2 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 2 S(0.001)S(0.001)Y(0.004)S(0.493)S(0.493)PT(0.045)S(0.135)LS(0.828)PR 96.135 0.03115 0.0 18833.0 26805.0 29442.0 40513.0 31760.0 31686.0 28196.0 31743.0 26928.0 27887.0 True False 24821.502249265002 35469.192049655525 29051.579842938936 31173.35376961049 27350.672217505482 29704.669410982762 30705.389377110314 26837.84873157398 28351.35910539845 26910.684618142175 0.9223660639436604 1.318033805269433 1.0795555837830098 1.1584006208669468 1.0163499221817154 1.1038243668820298 1.141011082133893 0.9972934212710779 1.0535354082476602 1.0 14.715891473710048 -7.849802281915837 0.6226174682989385 0.9982267024340665 1.1222821734972594 0.10560614975521754 0.09915597761471659 1.476650495312293 1.203920107358267 0.09079649576792143 0.047857512403995314 1.4131807667042347e-08 7.849802281915837 0.12405547106319292 SSYSS(ph)PTS(ph)LSPR ddPTM_PC-9_Lapatinib_30min_R1 2 SSYSSPTSLSPR 12 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;A0A087WXJ0;C9J760;Q96JY6-2 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 2 SSYS(0.085)S(0.912)PT(0.004)S(0.818)LS(0.181)PR;S(0.003)S(0.002)Y(0.001)S(0.095)S(0.896)PT(0.003)S(0.516)LS(0.483)PR 166.24 0.0013952 16721500.0 161649.0 127325.0 163115.0 137501.0 150736.0 134906.0 118824.0 115992.0 147938.0 115977.0 True False 159343.8556172037 127030.18678532461 149704.31434210823 147613.2822298897 141870.00483837817 129136.38486124584 124976.1253097029 121381.41176961438 131275.66458379716 136023.46992036133 1.1714438376737186 0.9338843279008977 1.100577087393497 1.085204504166185 1.0429818098409036 0.9493684063261456 0.9187835406851009 0.8923563840907783 0.9650956901824083 1.0 17.053496074562403 -6.74265919686865 3.556526143088879 0.9347709472855138 1.0648054654672636 0.49771534531123096 0.06121147440604024 0.19030862625741551 5.0869491258862505 0.020952177684966565 0.019782919369880223 1.8085928231008064e-07 6.74265919686865 0.13003451818174983 SSYSS(ph)PTSLSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSYSSPTSLSPR 12 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;A0A087WXJ0;C9J760;Q96JY6-2 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 SSYS(0.027)S(0.844)PT(0.118)S(0.011)LSPR;SSYS(0.018)S(0.831)PT(0.12)S(0.031)LSPR 167.84 0.00034048 23136000.0 96127.0 95322.0 108281.0 127408.0 140764.0 133179.0 129427.0 123730.0 121652.0 107326.0 True False 112399.40250520715 104784.93819884873 110862.82969797935 120269.7428223091 113182.30468282895 126194.85879176977 117166.73758966562 120482.2186027715 123430.93035702733 126783.35420785173 0.8865470014378766 0.8264881368185112 0.8744273283401867 0.9486240806118439 0.8927221194769395 0.9953582596094029 0.9241492175509065 0.9502999771188417 0.9735578548795266 1.0 16.952005816300527 SSYSSPTSLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 SSYSSPTSLSPR 12 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;A0A087WXJ0;C9J760;Q96JY6-2 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 SSYSSPTSLS(1)PR;SSYSSPTSLS(1)PR;SSYSSPTSLS(1)PR 186.76 2.4437e-12 75562000.0 90612.0 95871.0 127747.0 148907.0 164813.0 136527.0 105636.0 136240.0 119648.0 115791.0 True False 119424.73115331579 126859.42589041332 126052.99131159286 114578.79174021649 141931.55982946214 127989.94510740554 115037.39935595215 115187.23848374879 125972.34901376689 111737.19233403736 1.0688001788723722 1.1353375115348179 1.1281202675538735 1.0254310972633374 1.2702266529586583 1.1454551741803276 1.0295354389436318 1.0308764349420696 1.127398553537784 1.0 16.76974994911067 -7.259122133949733 24.960178179845506 1.049525641510143 1.1308740095991259 0.2679286568492263 0.06625332149808917 298.08953701072653 3210897.1897698776 0.026545587109345986 0.01950453155546093 5.5065281794411605e-08 7.259122133949733 0.08134836808898283 SSYSSPTSLS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SSYSSPTSLSPR 12 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;A0A087WXJ0;C9J760;Q96JY6-2 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 SSYSSPTSLS(1)PR;SSYSSPTSLS(1)PR 185.57 2.6156e-35 0.0 61945.0 66685.0 77790.0 99084.0 97076.0 70899.0 94727.0 81346.0 82724.0 47477.0 True False 72431.0650304812 73305.04609418838 79644.80862021775 93532.6447146624 78054.6546658968 67180.93162944364 85753.77279591025 79210.7536932115 83933.68200156758 56084.20427227481 1.2914699596850205 1.3070533324911 1.4200934051513345 1.6677181379018013 1.3917404317080249 1.1978583364274367 1.529018266526473 1.4123540615582788 1.496565442813283 1.0 15.775306882525136 -6.521860042733813 24.999959277788992 1.357686644610643 1.4278506120164487 0.04964302345930571 0.1720184481000793 167.07090093342228 4100256.3969451515 0.05689705334242323 0.05760381925770566 3.007045207456159e-07 6.521860042733813 0.07016396740580566 SSYSSPTSLS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 SSYSSPTSLSPR 12 0 Q96JY6;Q96JY6-3;Q96JY6-5;C9JSR2;C9JS55;Q96JY6-4;C9J0X3;C9K0F0;A0A087WXJ0;C9J760;Q96JY6-2 Q96JY6 PDLIM2 PDZ and LIM domain protein 2 1 SSYSSPTSLS(1)PR;SSYSSPTS(0.002)LS(0.998)PR;SSYS(0.002)S(0.027)PT(0.048)S(0.162)LS(0.762)PR 201.09 5.922399999999999e-47 40288000.0 112307.0 106314.0 129637.0 113651.0 109714.0 106149.0 106757.0 95637.0 113464.0 90071.0 True False 110705.48158541854 106067.83646491251 118978.74627329118 122009.27366862209 103260.83822602322 101609.25471540458 112284.35509398721 100080.64416003335 100684.48949111099 105639.65233793668 1.0479538614087491 1.004053251951323 1.126269763674376 1.1549571677718107 0.9774818066959957 0.9618476818757502 1.0628997029902598 0.9473776365704015 0.9530937225070152 1.0 16.68879193312602 -6.292121744859188 24.56224317551749 0.98401131605124 1.080716089335433 0.49891950791093875 0.04883465337588056 512.9057665036464 410596.2581293888 0.01624852501832082 0.018426244959514542 5.10361911238707e-07 6.292121744859188 0.09670477328419302 SSYYVVSGNDPAAEEPSR ddPTM_PC-9_Lapatinib_30min_R1 1 SSYYVVSGNDPAAEEPSR 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 0 103.3 0.0018934999999999998 7417600.0 11346.0 10341.0 8024.0 12560.0 8788.4 9090.5 10423.0 8051.6 9652.0 9974.3 False True 11184.203959398426 10317.056049849143 7364.297693535721 13483.704298931745 8271.483590659185 8701.720505990503 10962.651939869318 8425.706729810912 8564.89011993409 11698.344465080663 0.9560501481883239 0.8819244535536939 0.6295162290286468 1.1526164526254417 0.7070644581675131 0.7438420480748343 0.9371113983344076 0.7202477884765223 0.7321454882355469 1.0 13.514016755425299 ST(ph)DSPGADAELPESAAR ddPTM_PC-9_AZD4547_30min_R2 1 STDSPGADAELPESAAR 17 0 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 S(0.2)T(0.687)DS(0.113)PGADAELPESAAR 273.44 3.962399999999999e-82 20015000.0 19859.0 18776.0 19876.0 23727.0 18235.0 31636.0 19084.0 21985.0 19475.0 18886.0 True False 26173.748907139267 24844.974815308065 19612.431253252307 18257.106728495753 15703.385009011721 29657.795918886928 20782.439029393267 18587.723415041222 20504.408740999508 18224.806888451014 1.436160562212896 1.3632503744691102 1.0761393178701182 1.001772300811879 0.8616489110215424 1.6273311481660173 1.140337955655542 1.0199133263145952 1.1250823598022905 1.0 14.153615907267637 -5.17980606438368 4.505013216706447 1.114614933980448 1.4161495752353737 0.2747400906174554 0.1911164173260773 0.31027230808425627 11.334967253030396 0.05127455484583001 0.14757681427682692 6.6098854870428095e-06 5.17980606438368 0.3015346412549256 ST(ph)ECLLLSLLHR ddPTM_PC-9_Lapatinib_30min_R1 1 STECLLLSLLHR 12 0 Q5TB30;H0YES2 Q5TB30 DEPDC1 DEP domain-containing protein 1A 1 S(0.427)T(0.573)ECLLLSLLHR 79.885 0.031238 558000.0 2289.5 1315.3 2825.9 1210.1 2715.5 2840.9 1963.6 2762.8 2178.3 1218.3 True False 2256.8513101571198 1312.2545036617905 2593.565410289454 1299.0947907752632 2555.779628878412 2719.4013294613533 2065.2656000314114 2891.16977409727 1932.956915484091 1428.8815317172914 1.5794530617557487 0.918378798055194 1.815101779062394 0.9091689982261546 1.7886574723985451 1.9031678057963697 1.4453721699022075 2.023379622397763 1.3527761907321876 1.0 10.480670592496113 -5.270375719096585 24.961336912268823 1.5636649253171317 1.2489159130304701 0.07397953859201911 0.3825574406764922 1311.9006225659514 3664458.2407043115 0.09597285004994241 0.20467611732208876 5.365673975453969e-06 5.270375719096585 -0.31474901228666163 ST(ph)ELLIR ddPTM_PC-9_AZD4547_30min_R2 1 STELLIR 7 0 K7EMV3;A0A590UJJ6;B4DEB1;K7EK07;K7ES00;P84243;K7EP01;Q71DI3;Q16695;P68431;Q5TEC6;Q6NXT2 K7EMV3 H3F3B;H3F3A;HIST2H3A;HIST3H3;HIST1H3A;HIST2H3PS2;H3F3C Histone H3;Histone H3.3;Histone H3.2;Histone H3.1t;Histone H3.1;Histone H3.3C 1 S(0.202)T(0.798)ELLIR 119.21 0.01611 2136400.0 14425.0 21354.0 18679.0 27064.0 17413.0 13285.0 8673.5 17784.0 10409.0 13121.0 True False 19011.849941360793 28256.26289977035 18431.304255358224 20824.81293463182 14995.505520258905 12454.286849867638 9445.424697204075 15035.89143566492 10959.198489605333 12661.637783721575 1.50153165539164 2.231643597963132 1.455680897699855 1.6447171598452472 1.1843258965706525 0.9836236877570043 0.745987593275459 1.187515524650042 0.8655435163131122 1.0 13.62817640908908 -6.235993334476136 1.4069279483465604 0.9446377952186779 1.811307217240004 0.7241446753527162 0.22030889949773524 0.2049560143992831 0.8160247979941736 0.07983611077737067 0.1139358169196239 5.807733311247594e-07 6.235993334476136 0.8666694220213261 ST(ph)ELLIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STELLIR 7 0 K7EMV3;A0A590UJJ6;B4DEB1;K7EK07;K7ES00;P84243;K7EP01;Q71DI3;Q16695;P68431;Q5TEC6;Q6NXT2 K7EMV3 H3F3B;H3F3A;HIST2H3A;HIST3H3;HIST1H3A;HIST2H3PS2;H3F3C Histone H3;Histone H3.3;Histone H3.2;Histone H3.1t;Histone H3.1;Histone H3.3C 1 S(0.226)T(0.774)ELLIR 129.42 0.010818000000000001 1854800.0 21554.0 37127.0 23695.0 32117.0 35529.0 30798.0 35909.0 31263.0 24708.0 23080.0 True False 25202.666489095056 40812.72319620495 24259.978663787922 30317.588614718883 28567.34749706055 29182.8986632196 32507.439561353513 30442.37937588656 25069.30775705639 27264.22129882054 0.9243860740737654 1.496933389327005 0.8898100700509433 1.111991730203218 1.047796200887512 1.0703734518352837 1.1923113154440173 1.116568818974614 0.9194947283581835 1.0 14.734721330371643 -7.734532733348332 0.17377671744089843 0.9482413409055224 1.1884843727374954 0.044313077684096425 0.16428079540279594 12.39079842950082 2.1102221132699204 1.1003145230138511 1.2825479731888987 1.842753592965656e-08 7.734532733348332 0.24024303183197304 ST(ph)ELVLSPDMPR ddPTM_PC-9_AZD4547_30min_R2 1 STELVLSPDMPR 12 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 S(0.402)T(0.598)ELVLSPDMPR 132.79 0.00029329 7356000.0 23152.0 20956.0 26695.0 35467.0 31279.0 27306.0 26059.0 31703.0 25270.0 27220.0 True False 30513.85440848424 27729.617183084567 26341.00685779685 27290.631109687634 26936.450764841113 25598.551503386207 28378.200517027857 26804.029812465407 26605.720610272532 26267.036085123193 1.161678626762397 1.0556812383864556 1.0028161065616212 1.0389688056637716 1.0254849720215313 0.9745504373020756 1.0803731500220675 1.0204436361073244 1.012893899564906 1.0 14.680965798653123 -4.785959977836049 2.9152893543683356 1.0217426690138767 1.185086139872706 0.7247796790049252 0.02633717037000462 0.20338993823166474 2.4668757835605213 0.006587585025616147 0.07916532919151009 1.6369673682851165e-05 4.785959977836049 0.16334347085882928 ST(ph)ELVLSPDMPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STELVLSPDMPR 12 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 S(0.392)T(0.607)ELVLS(0.001)PDMPR;S(0.391)T(0.609)ELVLSPDMPR 141.37 0.00021391 11007500.0 43511.0 50416.0 52481.0 59669.0 57684.0 52290.0 59788.0 41972.0 38791.0 45419.0 True False 50876.55291857726 55420.96729226355 53732.34607530085 56325.93937950809 46381.23428805876 49547.820348715904 54124.44781236471 40870.27947300997 39358.24498963795 53653.10516339385 0.9482499244664229 1.0329498567414859 1.0014769119450901 1.0498169529605874 0.8644650509380676 0.9234846743319737 1.0087850022386486 0.7617504960532038 0.7335688189859154 1.0 15.711374048652273 -7.035550412112939 0.9300900868182894 0.8363639830782408 1.002684734950815 0.27724262182538173 0.09024187165363354 0.6859531737996272 1.2197018720599246 0.06308223756749975 0.04428373579081691 9.214029277524806e-08 7.035550412112939 0.16632075187257422 ST(ph)ELVLSPDMPR ddPTM_PC-9_Lapatinib_30min_R1 1 STELVLSPDMPR 12 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 S(0.384)T(0.616)ELVLSPDMPR 148.13 0.00028318 3641500.0 47663.0 45303.0 45434.0 32582.0 39611.0 42368.0 34063.0 36650.0 39584.0 22845.0 True False 46983.316879676284 45198.10368690804 41698.59190031179 34978.18897036578 37281.15885822234 40556.019404631836 35826.61546846097 38352.89279740299 35125.633082000764 26793.72781095092 1.7535192270063158 1.6868912010233614 1.556281835604416 1.3054618311107038 1.3914136592439772 1.5136385534250334 1.337126947069239 1.4314130929451219 1.310964764956838 1.0 14.709607696833803 -1.522878745280528 0.06811428380198971 0.5449493149104547 3.479354794745305 0.794237157470634 0.09277180949643869 134.40869356820164 0.6802327705384626 5.269488695597456 38.02851276360851 0.02999999999998685 1.522878745280528 2.93440547983485 ST(ph)FHAGQLR ddPTM_PC-9_AZD4547_30min_R2 3 STFHAGQLR 9 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 S(0.211)T(0.789)FHAGQLR;S(0.224)T(0.776)FHAGQLR;S(0.05)T(0.95)FHAGQLR 112.85 0.0044895000000000004 52045600.0 56289.0 42215.2 236862.0 354842.0 238233.0 192399.0 180413.0 244946.0 162647.0 243813.0 True False 74187.73111606634 55860.43783676995 233721.05511711858 273038.65915424994 205158.4601509122 180368.26011499306 196469.40749370813 207095.2239991221 171244.18836956852 235277.181080901 0.3153205541448433 0.23742395067867678 0.9933859885746958 1.1604978345110506 0.8719862215637803 0.7666202871283667 0.8350550894527733 0.8802180604497789 0.7278401908032276 1.0 17.8440018785612 -5.258444929131668 24.99999999370718 0.9007567393220948 0.276372186853873 0.8159056266178542 0.119326372646187 107.15309031664715 894585.8992683946 0.03360993106831842 0.08130696260948767 5.51512132642672e-06 5.258444929131668 -0.6243845524682218 ST(ph)FHAGQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 STFHAGQLR 9 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 S(0.162)T(0.838)FHAGQLR;S(0.203)T(0.797)FHAGQLR;S(0.022)T(0.978)FHAGQLR 143.4 0.0012724 52448000.0 77301.0 108123.0 250044.0 278770.0 262438.0 279270.0 217150.0 248621.0 252460.0 157921.0 True False 90386.53253565641 118856.73687998683 256005.99725715007 263151.42068453424 211015.15782694673 264624.5895732624 196579.97997014437 242094.96218572435 256151.74989260407 186550.82719805196 0.484514241471025 0.6371279005576448 1.372312313498138 1.4106151371023359 1.1311402956306496 1.4185120138455525 1.0537609665029517 1.2977426357306037 1.3730936160398806 1.0 17.50920923176053 -5.194882430197294 4.94933807532959 1.267235092774443 0.5318804184269788 0.7881991788429663 0.14471294093008139 0.08491497450425878 4.080332802516654 0.03555719374572476 0.09921386374392727 6.38436296745291e-06 5.194882430197294 -0.7353546743474642 ST(ph)FHAGQLR ddPTM_PC-9_Lapatinib_30min_R1 2 STFHAGQLR 9 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 S(0.026)T(0.974)FHAGQLR;S(0.188)T(0.812)FHAGQLR 111.27 0.0047111 65626000.0 194635.0 119540.0 313046.0 141564.0 194258.0 217758.0 134472.0 127648.0 272660.0 85074.0 True False 191859.4692083128 119263.21247451546 287308.56627250474 151975.0888036603 182832.1263659224 208444.99795869083 141434.30218345084 133578.99208193476 241950.15956291227 99778.92754602066 1.9228455739797583 1.1952745475191457 2.8794513364556913 1.5231180825587187 1.8323721337012309 2.089068334218671 1.4174766722985435 1.3387495272518801 2.4248622982174117 1.0 16.6064475424581 -7.265220225120694 24.8732143715172 1.5735012621008384 1.898027547845413 0.1006933145597495 0.5265174376342637 863.4345673238839 5680275.301054949 0.20756181538199558 0.14605701491326292 5.429749261012801e-08 7.265220225120694 0.32452628574457454 ST(ph)FHGQPR ddPTM_PC-9_AZD4547_30min_R2 1 STFHGQPR 8 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;A2SY06 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 S(0.19)T(0.81)FHGQPR 83.499 0.031389 15544000.0 6350.2 4853.6 21293.0 33081.0 21015.0 21936.0 16041.0 27083.0 16989.0 23180.0 True False 8369.431507634608 6422.431282678908 21010.64090740096 25454.686546355108 18097.42999530471 20564.338452291813 17468.617924465387 22897.944655426953 17887.003856269082 22368.47525544288 0.3741619136779602 0.2871197615991349 0.9392969644763104 1.1379714645575256 0.8090596157599563 0.9193446677724683 0.780948085418329 1.0236703393475708 0.7996523523397809 1.0 14.449179298155599 -5.263153467197515 24.959671938604814 0.925029465249875 0.3306407947596429 0.8319508414539973 0.1070732621989394 49.74050321032671 724308.8567554586 0.027399880041773902 0.06225701363730899 5.455650400073614e-06 5.263153467197515 -0.594388670490232 ST(ph)FSTNYR ddPTM_PC-9_AZD4547_30min_R2 1 STFSTNYR 8 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.17)T(0.67)FS(0.097)T(0.063)NYR 88.37 0.026961000000000002 6469000.0 42866.0 59721.0 68360.0 95595.0 83749.0 66144.0 55327.0 72067.0 51267.0 65404.0 True False 56496.49633181085 79024.64534219273 67453.50173436949 73557.04967802721 72121.89696296807 62008.00522375961 60250.995817398994 60930.701084911394 53976.86895634514 63114.225867428235 0.8951467843475105 1.2520892755332913 1.06875273850393 1.1654591126972575 1.1427201391087405 0.9824727210313527 0.9546341571859969 0.9654036035060726 0.8552250814217992 1.0 15.945677603065066 -6.871301510510585 4.365079280186922 0.9443112777776596 1.1141654626858681 0.41222841512469544 0.09186873288831783 0.2017612923574118 6.74636605162679 0.03152258085443464 0.02781090759484926 1.3449263099198264e-07 6.871301510510585 0.16985418490820858 ST(ph)LSPPEASPGPPAAPR ddPTM_PC-9_AZD4547_30min_R2 1 STLSPPEASPGPPAAPR 17 0 Q6NUJ5-2;Q6NUJ5 Q6NUJ5-2 PWWP2B PWWP domain-containing protein 2B 1 S(0.209)T(0.667)LS(0.122)PPEAS(0.001)PGPPAAPR 118.71 0.00067496 0.0 18897.0 18071.0 20623.0 26305.0 23501.0 21085.0 22355.0 24765.0 18738.0 19862.0 True False 24905.852917982316 23912.09735233447 20349.52554517117 20240.788658198708 20238.291806788275 19766.551616820423 24344.55169262665 20938.13829308601 19728.452425614814 19166.637425522284 1.299437786871144 1.2475895913016612 1.0617159960501863 1.0560427585094339 1.0559124878023194 1.0312999186022738 1.2701524608698163 1.0924262732285421 1.0293121316806682 1.0 14.226309633872114 -5.175383277195516 4.116630748058123 1.0819078239255884 1.2869264521546835 0.5605533787629808 0.07064089917676886 0.17525274375440694 5.382395391552044 0.019038342163850423 0.05645170986764265 6.677543453045984e-06 5.175383277195516 0.2050186282290951 ST(ph)LSPPEASPGPPAAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STLSPPEASPGPPAAPR 17 0 Q6NUJ5-2;Q6NUJ5 Q6NUJ5-2 PWWP2B PWWP domain-containing protein 2B 1 S(0.214)T(0.771)LS(0.015)PPEASPGPPAAPR 119.77 0.00023092 3218000.0 13822.0 13121.0 12711.0 15016.0 20526.0 11431.0 16385.0 10678.0 12719.0 11901.0 True False 16161.79160305613 14423.56616633192 13014.078446735939 14174.70220252884 16504.077647123882 10831.538236874578 14832.894182872746 10397.713814276201 12904.991313016038 14058.557091735838 1.1496052900447837 1.025963480619974 0.925705131886267 1.0082615242826931 1.173952457526784 0.7704587438238433 1.0550794143441713 0.7396003548890788 0.9179456489600978 1.0 13.779160909705235 -6.7634942356410015 24.99999999992754 0.8902457815250718 1.0450218688140283 0.3438959814193143 0.10978992575460975 66.02777182817495 803304.9215205143 0.03682986971514419 0.03409574526184085 1.7238749717419441e-07 6.7634942356410015 0.15477608728895642 ST(ph)LSPPEASPGPPAAPR ddPTM_PC-9_Lapatinib_30min_R1 1 STLSPPEASPGPPAAPR 17 0 Q6NUJ5-2;Q6NUJ5 Q6NUJ5-2 PWWP2B PWWP domain-containing protein 2B 1 S(0.16)T(0.759)LS(0.081)PPEAS(0.001)PGPPAAPR 143.97 0.00027855 5826500.0 25892.0 31230.0 36477.0 23086.0 33705.0 30906.0 29207.0 25980.0 27695.0 26589.0 True False 25522.775331988716 31157.688853765496 33478.001865291924 24783.821452638396 31722.538166579583 29584.222425404834 30719.195549051426 27187.12564465294 24575.69745872095 31184.873222384518 0.8184344746243334 0.9991282834974134 1.0735333642870608 0.7947385668654429 1.0172412098763681 0.9486722044510113 0.9850671936354441 0.8718049116562708 0.7880646903217328 1.0 14.928558773409684 -7.77742156320566 23.881739551569154 0.8724510044946119 0.951683053591679 0.07587296924123577 0.09396646223987619 309.0970662588981 461864.1175896184 0.04923437768123656 0.023791315861218406 1.6694692984828035e-08 7.77742156320566 0.07923204909706716 ST(ph)MLPAAVRCSES(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STMLPAAVRCSESR 14 1 E9PDM8;O94855;O94855-2 E9PDM8 SEC24D Protein transport protein Sec24D 2 S(0.41)T(0.59)MLPAAVRCS(0.001)ES(0.999)R 130.64 0.00066352 11532000.0 23955.0 37402.0 33006.0 24500.0 26371.0 17174.0 24018.0 13431.0 19307.0 14666.0 True False 28010.10836718343 41115.023378793274 33792.988215952064 23127.344430071687 21203.791855807456 16273.365206900888 21742.84116473834 13078.450481320808 19589.32834974452 17324.82970400788 1.6167609636418907 2.3731848497928865 1.9505524033020933 1.33492477705114 1.2238961200814706 0.9393088119726943 1.255010383144396 0.7548963369201415 1.1307082773352037 1.0 14.08055355087928 -5.893004772331278 2.2025482540657864 1.0405102743204342 2.044422006358238 0.7844971805747359 0.21757449462084372 0.12600834019831839 1.2429530913819888 0.064776336007313 0.109882405479296 1.279367245498889e-06 5.893004772331278 1.0039117320378037 ST(ph)PAMMNGQGSTTSSSK ddPTM_PC-9_AZD4547_30min_R2 1 STPAMMNGQGSTTSSSK 17 0 Q6ZN18-2;Q6ZN18;F5GZR7;A0A669KBC9;A0A669KBL4;G5EA50;Q6ZN18-3 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 S(0.423)T(0.577)PAMMNGQGSTTSSSK 98.421 0.0012054000000000001 2846700.0 8604.2 8411.6 9121.7 11200.0 14141.0 13529.0 9862.5 12108.0 11471.0 13059.0 True False 11340.15662152212 11130.485202196707 9000.740297987099 8618.013038275063 12177.766241427727 12683.0294912954 10740.243393805871 10236.986814160533 12077.333641489357 12601.808384850241 0.8998832766855219 0.8832450758081402 0.714241958226225 0.6838711377833316 0.9663506910696807 1.0064451945280173 0.8522779481965205 0.8123426814255745 0.9583809936364845 1.0 13.621343157770822 -6.2823830886399765 24.98940751057429 0.9229229204661663 0.7958007984693418 0.38650299873059646 0.08422503464270806 1009.2515099403688 1204205.7663491976 0.028604181866929656 0.03246605029697094 5.219355895309581e-07 6.2823830886399765 -0.1271221219968245 ST(ph)PAMMNGQGSTTSSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STPAMMNGQGSTTSSSK 17 0 Q6ZN18-2;Q6ZN18;F5GZR7;A0A669KBC9;A0A669KBL4;G5EA50;Q6ZN18-3 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 S(0.21)T(0.79)PAMMNGQGSTTSSSK;S(0.115)T(0.885)PAMMNGQGSTTSSSK 113.29 0.00018115 4949300.0 7471.4 7578.5 7582.6 10632.5 10677.9 10618.2 10394.0 10025.2 10105.5 9137.9 True False 8736.160453123539 8330.843395438344 7763.3979411706405 10036.795496030096 8585.642146946519 10061.3628997272 9409.405073956628 9762.049122577428 10253.273819772276 10794.528934423395 0.8093137279260249 0.7717653494699116 0.7191974738622842 0.9298039365129762 0.7953697839992989 0.9320798490466636 0.8716827877454056 0.9043515638229082 0.9498583849337718 1.0 13.398012666096546 -6.706639874911413 0.2820091077085579 1.0088506940505422 0.712202778332446 0.6268545325619399 0.0523725521648229 1.8439730484217571 0.3031611676436281 0.07852486425394438 0.18796392419759064 1.964989007008468e-07 6.706639874911413 -0.2966479157180961 ST(ph)PAMMNGQGSTTSSSK ddPTM_PC-9_Lapatinib_30min_R1 2 STPAMMNGQGSTTSSSK 17 0 Q6ZN18-2;Q6ZN18;F5GZR7;A0A669KBC9;A0A669KBL4;G5EA50;Q6ZN18-3 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 S(0.243)T(0.757)PAMMNGQGSTTSSSK;S(0.044)T(0.956)PAMMNGQGSTTSSSK 126.63 3.1968e-05 3072500.0 8048.8 5966.799999999999 6448.9 5162.4 8623.900000000001 6181.5 5818.7 5818.6 6860.2 6149.1 True False 7934.0226360308525 5952.984241199099 5918.6963354738855 5542.060117261561 8116.659157239746 5917.131654780303 6119.963814882241 6088.953397843631 6087.532034891408 7211.9637418392795 1.1001195957215704 0.8254318039154339 0.8206774946936201 0.7684536855211864 1.125443699911023 0.8204605384318316 0.8485849394081197 0.8442850818175016 0.8440879977772732 1.0 12.816176428298654 ST(ph)PDSTYSESFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STPDSTYSESFK 12 0 Q6ISB3-2;Q6ISB3 Q6ISB3-2 GRHL2 Grainyhead-like protein 2 homolog 1 S(0.021)T(0.979)PDSTYSESFK;S(0.207)T(0.793)PDSTYSESFK 173.76 0.00019677 49136000.0 147088.0 221510.0 164126.0 148487.0 176518.0 110204.0 156373.0 89307.0 111473.0 94067.0 True False 171987.09327957736 243500.04889140962 168039.38629132122 140167.75479134914 141930.56504506528 104424.70823694576 141560.2173975197 86962.78587858824 113103.08173880294 111120.60246603793 1.5477516271759073 2.191313253236106 1.5122252990185103 1.2614020413918199 1.2772659785429428 0.9397420993002746 1.2739331344138916 0.7825982216499132 1.017840789455501 1.0 16.761766800794682 -5.805392597552921 1.2858802594003103 1.0199243913038971 1.8920068224970519 0.7132536886152596 0.20508601330773168 0.23648412415844564 0.7818521643074985 0.06924852837233009 0.1647994849020082 1.565335383926432e-06 5.805392597552921 0.8720824311931548 ST(ph)PDSTYSESFK ddPTM_PC-9_Lapatinib_30min_R1 1 STPDSTYSESFK 12 0 Q6ISB3-2;Q6ISB3 Q6ISB3-2 GRHL2 Grainyhead-like protein 2 homolog 1 S(0.374)T(0.626)PDSTYSESFK 135.1 0.00014517 39743000.0 43222.0 98835.0 75663.0 75191.0 92016.0 95255.0 101040.0 105250.0 74683.0 94085.0 True False 42605.64635405596 98606.15362990444 69442.28020762616 80720.796969823 86603.7997904164 91181.16570025028 106271.35680748294 110140.29923401523 66271.41409314521 110347.46688961754 0.38610443497244135 0.8935968936064645 0.629305612217546 0.7315147256671455 0.7848281635413312 0.8263095499188972 0.9630611359097894 0.9981225880263337 0.6005703253653991 1.0 16.75169398626791 -3.9655459817792735 0.3933259528951222 0.8966151013470919 1.0142734502460796e-16 0.3852717665705794 0.14813104459954005 12.625837752167275 0.940674464824094 0.11529307330026742 6.058305664153511 0.00010825650903591126 3.9655459817792735 -0.8966151013470918 ST(ph)PDSTYSESFKDAATEK ddPTM_PC-9_Lapatinib_30min_R1 1 STPDSTYSESFKDAATEK 18 1 Q6ISB3-2;Q6ISB3 Q6ISB3-2 GRHL2 Grainyhead-like protein 2 homolog 1 S(0.427)T(0.437)PDS(0.109)T(0.022)Y(0.006)SESFKDAATEK 83.167 0.0016886 28108000.0 192230.0 95498.0 111550.0 109160.0 93737.0 91101.0 59900.0 69894.0 92491.0 72139.0 True False 189488.76494933543 95276.88024837954 102378.78959545222 117187.9905470854 88223.57395403268 87204.82259680328 63001.32890704906 73141.53040059174 82073.68960659175 84608.13003082451 2.2396046914203245 1.1260960408139051 1.210034893315258 1.3850677293587668 1.0427316372775404 1.030690816178454 0.7446250009791773 0.8644740212783896 0.970044954033266 1.0 16.36850867872925 -2.0860565699301894 0.9134259391083892 0.9828120017611489 199.99999998588947 0.8122328402548803 0.17179771103445868 136.50903697708378 0.9100050206042776 0.06201073520663779 55852.41157121147 0.008202446946938608 2.0860565699301894 199.01718798412833 up ST(ph)PGSNSADGGR ddPTM_PC-9_AZD4547_30min_R2 2 STPGSNSADGGR 12 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;H7C1R1;O15231-3 O15231-7;O15231-3 ZNF185 Zinc finger protein 185 1 S(0.224)T(0.775)PGSNSADGGR;S(0.077)T(0.922)PGS(0.001)NS(0.001)ADGGR 109.95 0.0030578000000000003 17222600.0 23256.0 19644.5 21542.4 27613.0 23834.0 24251.0 21676.1 27110.0 23380.0 24858.0 True False 30650.924245149832 25994.20045586488 21256.73370044588 21247.24946659727 20525.060504786692 22734.5811363297 23605.230907830206 22920.772425825227 24615.819068784007 23987.72898618635 1.2777751600745768 1.0836457453239523 0.8861503193022919 0.8857549407379406 0.8556483407248063 0.9477587957335064 0.984054427220834 0.9555207347483564 1.0261838076859777 1.0 14.55000895796213 -4.915556112401415 2.7974219158220714 0.9381541676041083 1.2953091425643526 0.7978739979261387 0.05237287250534519 0.14771710210786995 1.9475544410232863 0.014847547493839713 0.1062761645023593 1.214629675831223e-05 4.915556112401415 0.3571549749602443 ST(ph)PGSNSADGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STPGSNSADGGR 12 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;H7C1R1;O15231-3 O15231-7;O15231-3 ZNF185 Zinc finger protein 185 1 S(0.23)T(0.769)PGS(0.001)NSADGGR;S(0.023)T(0.977)PGSNSADGGR 121.21 0.0011183 14822200.0 31927.0 34712.0 36083.0 30465.0 42566.0 33425.0 30386.0 31786.0 28699.0 26998.0 True False 37331.6105130063 38157.97795638394 36943.35556553954 28758.144818862642 34225.49786258771 31672.13415865039 27507.618104410813 30951.651180050867 29118.6685818262 31892.523683949606 1.1705442593053241 1.1964552675267752 1.1583704046642078 0.9017205757641441 1.0731511310223534 0.9930896178840143 0.8625099216671409 0.9704986499901151 0.9130249104896209 1.0 14.960930643406822 -5.709202281474869 7.151462868432904 0.9601704209637041 1.1795138908096283 0.7571594582192163 0.05606276041196195 0.10536866593764342 11.60049934540805 0.015690978227745133 0.027112252616432245 1.9534293944401542e-06 5.709202281474869 0.21934346984592423 ST(ph)PGSNSADGGR ddPTM_PC-9_Lapatinib_30min_R1 1 STPGSNSADGGR 12 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;H7C1R1;O15231-3 O15231-7;O15231-3 ZNF185 Zinc finger protein 185 1 S(0.18)T(0.81)PGSNS(0.009)ADGGR 82.85 0.028517 7963400.0 9041.8 8001.4 11839.0 10527.0 8251.7 8299.5 9786.1 9088.5 10167.0 6487.8 True False 8912.86227393695 7982.873249904554 10865.643119861588 11301.190697042557 7766.351229466388 7944.5497320794475 10292.776374244946 9510.784889200462 9021.885396743672 7609.207585549898 1.171325946063389 1.0491070404051346 1.4279598759397436 1.4851994205682915 1.020651775122407 1.0440705740721772 1.3526738833871772 1.2499047742187654 1.1856537353346082 1.0 12.893530505549665 -6.284889437394975 24.96651611098037 1.160275696507646 1.276988918413719 0.16373933603098134 0.1528463103340769 1912.9567522544683 2036657.3661581555 0.05164131282190768 0.058590509789572635 5.189321317556838e-07 6.284889437394975 0.11671322190607314 ST(ph)PKEDDSSASTSQSTR ddPTM_PC-9_AZD4547_30min_R2 1 STPKEDDSSASTSQSTR 17 1 E7EX17;P23588-2;P23588;F8VX11 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 S(0.251)T(0.748)PKEDDS(0.001)SASTSQSTR 98.07700000000001 0.030579000000000002 0.0 5401.9 5788.5 6081.5 6964.9 5921.9 6196.4 6519.6 7134.5 6691.8 4921.5 True False 7119.591833499951 7659.519424712969 6000.85533641849 5359.249911632318 5099.746404434687 5808.938128454636 7099.83176986127 6032.02695950019 7045.514886419537 4749.1997829880165 1.4991139894773122 1.6128021087152264 1.2635508318504511 1.1284532461299155 1.0738117235460076 1.223140401307749 1.494953275137717 1.2701143845553424 1.4835162150173362 1.0 12.213468731501342 -5.270401464276946 22.67170930044524 1.2501104252987674 1.5559580434899236 0.4050467293005834 0.1518663556171172 167.03122904724464 422549.6199551954 0.04122718167642121 0.08823000679048137 5.365355905214572e-06 5.270401464276946 0.30584761819115625 ST(ph)PLSQPSANGVQTEGLDYDRLK ddPTM_PC-9_Lapatinib_30min_R1 1 STPLSQPSANGVQTEGLDYDRLK 23 1 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 1 S(0.469)T(0.524)PLS(0.006)QPSANGVQTEGLDYDRLK 64.289 0.020059 0.0 8632.7 4486.7 7888.7 6862.5 8175.6 11534.0 6186.1 6896.7 8094.8 6128.9 True False 8509.596114956703 4476.311321812026 7240.121537262615 7367.191142628912 7694.727281848031 11040.71770706721 6506.385989180237 7217.145859641184 7183.078381977056 7188.272198754093 1.1838166223632474 0.622724237207918 1.0072130460665512 1.024890396318858 1.0704557464006053 1.5359348396657604 0.9051390667020033 1.0040167734455152 0.9992774596407275 1.0 12.811429325167897 -5.686956006543238 2.8743756547355703 1.0925198555341076 0.8904431765094312 0.09243801765168402 0.20554266360148465 0.5225802267315919 8.695573037766486 0.05936168722875688 0.11131964710765377 2.056098865531607e-06 5.686956006543238 -0.2020766790246764 ST(ph)PPPNNLVNPVQELETER ddPTM_PC-9_AZD4547_30min_R2 1 STPPPNNLVNPVQELETER 19 0 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 S(0.413)T(0.587)PPPNNLVNPVQELETER 130.95 9.627299999999999e-05 4492800.0 19545.0 17933.0 21867.0 32362.0 25305.0 27162.0 20916.0 23945.0 22728.0 25120.0 True False 25759.90343874499 23729.491551071547 21577.029292356023 24901.44088791586 21791.83754609496 25463.555846150182 22777.48348033902 20244.850451360584 23929.355679868375 24240.556445932936 1.0626778925723452 0.9789169487094371 0.8901210391140258 1.0272635837983746 0.8989825623310385 1.0504526124614784 0.9396435899127477 0.8351644277026178 0.9871619792739216 1.0 14.565135196040755 -7.506343926456462 24.937447397843005 0.9241787278801163 0.9796093454748909 0.07421743588050844 0.06807253034174678 1469.332136936917 2216023.0344298715 0.028012777433044894 0.018335302411237927 3.116420650995106e-08 7.506343926456462 0.05543061759477452 ST(ph)PSSSTPSSR ddPTM_PC-9_Lapatinib_30min_R1 1 STPSSSTPSSR 11 0 H3BUV9;Q96S82 H3BUV9 UBL7 Ubiquitin-like protein 7 1 S(0.031)T(0.967)PSSST(0.001)PSSR 101.35 0.009218500000000001 3194000.0 4373.3 7190.3 7704.6 4908.0 7208.7 7896.7 7547.2 8588.4 6839.2 6137.3 True False 4310.935940035 7173.6513021207165 7071.1575286160605 5268.950692608042 6784.698438849497 7558.976549106785 7937.957087266782 8987.448417495654 6068.897276031211 7198.1241275617895 0.59889713814858 0.9966001106666992 0.9823611545597595 0.7319894182476103 0.9425648014141246 1.0501314530216674 1.1027813561691933 1.2485820275149881 0.843122064649213 1.0 12.813405265595716 -6.625466150081174 3.364605650332412 1.0687677761377288 0.8490518521321642 0.33642748968315894 0.143544751106725 0.28609526350670134 6.393131051668604 0.04923981974348101 0.04927522371654165 2.3688297566723406e-07 6.625466150081174 -0.2197159240055646 ST(ph)QGVTLTDLQEAEK ddPTM_PC-9_AZD4547_30min_R2 1 STQGVTLTDLQEAEK 15 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 S(0.023)T(0.977)QGVTLTDLQEAEK 187.0 2.6876999999999996e-38 0.0 13141.0 11259.0 17931.0 16308.0 18528.0 13659.0 18066.0 14449.0 15747.0 11373.0 True False 17319.564650219912 14898.251568254873 17693.22322409272 12548.442556088363 15955.707016559856 12804.900570744607 19673.83900152058 12216.239054988893 16579.354271862354 10974.83473167178 1.5781162152937176 1.357492111043885 1.6121630672972818 1.1433832821076912 1.4538448556782364 1.1667511068564451 1.7926319149704129 1.113113714572357 1.5106700626677085 1.0 13.421911594153565 -12.649310280757371 0.3355762341502841 1.7714300453795798e-15 1.424718126073587 0.25323345792439955 0.2122070088211915 126.81230805233726 3.494976989002774 89.70790564687279 0.16432353888711004 2.242279359716763e-13 12.649310280757371 1.4247181260735853 ST(ph)QGVTLTDLQEAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STQGVTLTDLQEAEK 15 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 S(0.017)T(0.983)QGVTLTDLQEAEK 124.92 0.00035134 0.0 11355.0 11263.0 8963.8 12538.0 12144.0 13355.0 12236.0 10583.0 10404.0 9087.5 True False 13277.177228527155 12381.116205426137 9177.53098740081 11835.536508744446 9764.470376433424 12654.640289866154 11076.91749903149 10305.207463615376 10556.138817565752 10734.991813389584 1.2368129812606603 1.15334193268628 0.8549173718003047 1.1025193791002401 0.9095927175514337 1.178821606000875 1.0318515087468838 0.9599641660426657 0.9833392517728098 1.0 13.390033470533117 -5.035815836977197 10.035381373583732 1.0083984319546042 1.2162415516454497 0.45197443688002037 0.08674122867976111 0.4277437266978171 119.76728115703669 0.02125802553446346 0.057904467836052256 9.208399721120314e-06 5.035815836977197 0.20784311969084546 ST(ph)QKSPATAPK ddPTM_PC-9_AZD4547_30min_R2 1 STQKSPATAPK 11 1 Q07960;H0YE29 Q07960 ARHGAP1 Rho GTPase-activating protein 1 1 S(0.119)T(0.703)QKS(0.177)PATAPK 111.63 0.018422 3317900.0 6643.5 8209.2 8922.6 11136.0 13098.0 10229.0 13843.0 8911.7 10939.0 11003.0 True False 8755.994806615627 10862.663360344428 8804.280494076722 8568.767249484923 11279.56878793724 9589.379012969228 15075.000182555606 7534.60153549343 11517.213207588882 10617.788319052544 0.8246533593916053 1.023062716446558 0.8292009813642953 0.8070199736520589 1.062327525186879 0.9031427944143565 1.4197872221190404 0.7096206205178673 1.0847092503174518 1.0 13.374195664200833 -6.27063969818192 24.550414546741862 1.0285656475730005 0.8788624843070273 0.16434978119218568 0.17520818081650022 1024.5749530687046 2734002.4043999324 0.05266584649257392 0.0605722179032257 5.362413525739809e-07 6.27063969818192 -0.14970316326597322 ST(ph)SADSASSSDTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSADSASSSDTSR 14 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.031)T(0.95)S(0.019)ADSASSSDTSR 152.0 0.00060874 1283900.0 4289.6 3136.5 4127.3 4818.1 5784.6 3608.8 4806.3 4277.9 2565.3 3629.3 True False 5015.744556538097 3447.870991593633 4225.710484872414 4548.157477490959 4651.149155098552 3419.548175070685 4351.0124694013575 4165.609657809715 2602.8126594292034 4287.263360477006 1.1699175289245676 0.8042125481206778 0.9856428517613287 1.0608532984978383 1.0848760069129646 0.797606278773185 1.014869417519818 0.9716243924297303 0.6071035158287107 1.0 12.065841327238957 -8.050576882793562 24.83917361173797 0.7988221774462744 0.9812007366201853 0.21345479092895125 0.14004311399144329 493.4812350492065 242353.92970763464 0.0888838388805877 0.033595864327452846 8.900678560846327e-09 8.050576882793562 0.18237855917391088 ST(ph)SATDTHHVEMAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSATDTHHVEMAR 14 0 H3BQP2;H3BNP3;H3BTL2;H3BS02;O14874-2;O14874-3;O14874 H3BQP2 BCKDK [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial 1 S(0.387)T(0.493)S(0.095)AT(0.024)DT(0.001)HHVEMAR 85.469 0.006876100000000001 2944600.0 3357.7 3330.5 6151.9 3394.6 4778.2 3973.4 3809.1 4431.1 3062.0 3088.1 True False 3926.0922924020824 3661.1300294923017 6298.584627210667 3204.4115674416876 3841.9460105956987 3765.0279092290643 3448.2744725041543 4314.788320138535 3106.775957265125 3647.9480846138495 1.0762467560767592 1.0036135231567715 1.726610269969727 0.878414794595655 1.0531800128406665 1.0320947069145607 0.9452641300045169 1.1827987186378155 0.8516502661780588 1.0 11.83286948274942 ST(ph)SFRGGMGSGGLATGIAGGLAGMGGIQNEK ddPTM_PC-9_AZD4547_30min_R2 1 STSFRGGMGSGGLATGIAGGLAGMGGIQNEK 31 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.055)T(0.264)S(0.245)FRGGMGS(0.228)GGLAT(0.209)GIAGGLAGMGGIQNEK 47.104 0.010717 6078400.0 10646.0 6835.0 13621.0 28264.0 21900.0 13831.0 10081.0 10905.0 11156.0 13981.0 True False 14031.206549443807 9044.280084290082 13440.376640196706 21748.171474446997 18859.56302151669 12966.145383554342 10978.18947051528 9219.88282197064 11745.683384574606 13491.52944548521 1.0400011804546885 0.6703672938516729 0.9962085243563233 1.6119871036359619 1.3978817670540558 0.9610582281235222 0.8137097810055189 0.6833830707797158 0.8705968757682375 1.0 13.719766285904022 -6.995101206606894 24.481420425385704 0.8258014061208248 1.1393420578850688 0.2547458646203773 0.2435796054694478 164.74872449795538 823312.783081103 0.09828365561570325 0.08635753817327334 1.0113437464616679e-07 6.995101206606894 0.31354065176424406 ST(ph)SFRGGMGSGGLATGIAGGLAGMGGIQNEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 STSFRGGMGSGGLATGIAGGLAGMGGIQNEK 31 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.065)T(0.316)S(0.316)FRGGMGS(0.283)GGLAT(0.019)GIAGGLAGMGGIQNEK;S(0.093)T(0.435)S(0.435)FRGGMGS(0.018)GGLAT(0.018)GIAGGLAGMGGIQNEK;S(0.316)T(0.335)S(0.335)FRGGMGS(0.009)GGLAT(0.004)GIAGGLAGMGGIQNEK 79.512 5.1805e-07 342806200.0 146083.4 82236.5 139203.9 270758.0 261618.0 339371.0 244966.4 362184.0 272601.0 211801.2 True False 170812.43434133165 90400.3962379054 142523.04890973022 255588.30706927946 210355.83094052682 321573.78733149846 221761.40918884837 352677.0537656685 276587.273914575 250199.08094262375 0.6827060822837425 0.3613138621345945 0.5696385788979534 1.021539751890182 0.8407538115168621 1.285271656954018 0.886339823285375 1.4095857284405662 1.1054687845875926 1.0 17.932716964492286 -5.897697086465425 1.4383655630606296 1.128923196044359 0.4864331873828986 0.6532607945331904 0.17886680033376237 0.2355193332834487 0.9897184024243516 0.059043065695837435 0.11734100889615619 1.2656187887856497e-06 5.897697086465425 -0.6424900086614604 ST(ph)SFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQSLNDR ddPTM_PC-9_AZD4547_30min_R2 1 STSFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQSLNDR 40 2 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.307)T(0.337)S(0.337)FRGGMGS(0.017)GGLAT(0.002)GIAGGLAGMGGIQNEKETMQSLNDR 55.12 6.0412e-05 11636000.0 8337.0 4151.4 19039.0 74818.0 43865.0 14419.0 9635.8 16676.0 8539.1 21264.0 True False 10987.992579627384 5493.258864948333 18786.5304201384 57569.86602657707 37775.10191501505 13517.377650601553 10493.367532981967 14099.10737635786 8990.45939308184 20519.55383225787 0.5354888643998513 0.2677084945342538 0.9155428316674673 2.8056100292041473 1.8409319336968484 0.6587559242809408 0.5113838058450284 0.6871059425372733 0.43814107590138446 1.0 14.32471174153794 -6.881710474461137 11.042120444113376 0.6264087022368283 1.2821833366179518 0.1709826531407519 0.6742535224777328 0.7375832840489558 67.64898667495872 0.27160320645114194 0.23956359365116978 1.3130749781728698e-07 6.881710474461137 0.6557746343811235 ST(ph)SGPRPGCQPSSPCVPK ddPTM_PC-9_Lapatinib_30min_R1 1 STSGPRPGCQPSSPCVPK 18 1 O14545 O14545 TRAFD1 TRAF-type zinc finger domain-containing protein 1 1 S(0.293)T(0.352)S(0.352)GPRPGCQPS(0.002)S(0.001)PCVPK 62.325 0.01518 24639000.0 19752.0 23949.0 18377.0 14111.0 17486.0 20330.0 23313.0 18631.0 16130.0 16170.0 True False 19470.332857926824 23893.547561922165 16866.113997271408 15148.770012916075 16457.50785879871 19460.533291544692 24520.03306861493 19496.664275809424 14313.269543569922 18964.962954829345 1.0266475555107155 1.2598784199490238 0.889330184163451 0.7987766730152513 0.8677848671783392 1.026130835999822 1.2929122575676326 1.0280359799408247 0.7547217243535459 1.0 14.211048933099017 -5.26979755650042 24.861732485798726 0.96381136410755 1.1432629913008638 0.1927135642610125 0.15183785239811715 942.8475450795983 2804544.682188105 0.04334965146111877 0.09276228768125942 5.3728218854408715e-06 5.26979755650042 0.17945162719331387 ST(ph)SHTSDFNPNSGSDQR ddPTM_PC-9_AZD4547_30min_R2 1 STSHTSDFNPNSGSDQR 17 0 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4;F8W0B5;F8WB06;F8VRK6 Q99700;F8WB06 ATXN2 Ataxin-2 1 S(0.13)T(0.74)S(0.127)HT(0.003)SDFNPNSGSDQR 130.64 1.9302e-05 0.0 948.79 386.49 3605.2 8519.9 2822.0 3386.2 2943.6 6128.7 2928.3 3796.5 True False 1250.485483942024 511.41533427611876 3557.3926924041643 6555.76868614283 2430.214011265757 3174.4603786994203 3205.574697491199 5181.650238515496 3083.0839597570643 3663.585690564665 0.34132830225933325 0.13959420564209452 0.9710139172030303 1.7894405208063784 0.6633430241647195 0.8664900037346045 0.8749828633043729 1.4143657815512576 0.8415482044537278 1.0 11.839040645093606 -5.301977969238772 6.103075417593038 1.0699555480000467 0.2395444558278402 0.5225795698001495 0.3106433376692478 0.13870156190183688 14.6327118853019 0.08242479930897859 0.17941880686346837 4.989097953657203e-06 5.301977969238772 -0.8304110921722064 ST(ph)SLSALVR ddPTM_PC-9_AZD4547_30min_R2 2 STSLSALVR 9 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5;X6R5W5;A0A0A0MRX3 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 S(0.053)T(0.626)S(0.317)LS(0.004)ALVR;S(0.127)T(0.436)S(0.436)LSALVR 153.1 0.00016331 47577000.0 57723.0 65887.0 101579.0 113161.0 86107.0 79705.0 67467.0 90864.0 67725.0 72486.0 True False 76077.71328701345 87183.68425949085 100231.99608946042 87073.47977002173 74152.52936501088 74721.03374999618 73471.43229910257 76823.05664700035 71304.8052366723 69948.28720302142 1.087627965302448 1.2464019884639141 1.4329442520664164 1.2448264746968756 1.060105005141682 1.0682325005774922 1.0503678536953363 1.0982835994829332 1.0193931558283 1.0 16.094001110649835 -6.245941141566328 5.157943207552055 1.0545367317130643 1.2671227378398369 0.5974147550401395 0.0816209749503043 0.1324216118632771 11.12276638681069 0.025923730024488712 0.03225530159955567 5.676215279844157e-07 6.245941141566328 0.2125860061267726 ST(ph)SPIIGSPPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSPIIGSPPVR 12 0 Q86TB9-4;Q86TB9;Q86TB9-2 Q86TB9-4 PATL1 Protein PAT1 homolog 1 1 S(0.179)T(0.729)S(0.092)PIIGSPPVR 86.11399999999999 0.022704 0.0 19699.0 25674.0 25158.0 23365.0 22704.0 17564.0 14646.0 13081.0 17339.0 12233.0 True False 23033.651627015082 28222.745046445063 25757.8621322463 22055.93480035206 18255.314182027716 16642.912920345127 13258.624852142453 12737.637610465157 17592.550072834747 14450.746063625282 1.5939420377051863 1.9530303087593512 1.7824589830059185 1.5262834668356806 1.2632783180640832 1.1516992165710989 0.9175045214804807 0.8814519025095682 1.2174146577191514 1.0 13.818856357708427 -6.287339951465813 1.3524912054828766 1.0031618715450235 1.8066838680350008 0.8776165099797062 0.12270273294924611 0.13240070779347968 0.49018144658825735 0.048001599473694125 0.06607475809760638 5.160122936574658e-07 6.287339951465813 0.8035219964899774 ST(ph)SPIIGSPPVR ddPTM_PC-9_Lapatinib_30min_R1 1 STSPIIGSPPVR 12 0 Q86TB9-4;Q86TB9;Q86TB9-2 Q86TB9-4 PATL1 Protein PAT1 homolog 1 1 S(0.128)T(0.436)S(0.436)PIIGSPPVR 128.57 0.00049152 13336000.0 54919.0 61480.0 67540.0 49825.0 48513.0 44792.0 50491.0 39304.0 32080.0 24436.0 True False 54135.84498908883 61337.646837319924 61987.121911939525 53489.29671132755 45659.560720227695 42876.3505752518 53105.176925639586 41130.207326306365 28466.812582623897 28659.730041076702 1.8889167801475575 2.140203231133281 2.162864821932941 1.8663573116237924 1.5931608795611787 1.4960486548128353 1.8529545410764974 1.435121938251208 0.9932686924065124 1.0 14.806737399818239 -7.4312759895760685 0.41833208315231346 0.9322301960928817 2.1408808191076427 0.7895413240503328 0.18205265593457268 0.5353486834050055 0.22720414545983195 0.21537960615686386 0.21575522572391564 3.704452329153558e-08 7.4312759895760685 1.2086506230147611 ST(ph)SPSAAGGQQK ddPTM_PC-9_AZD4547_30min_R2 1 STSPSAAGGQQK 12 0 Q2TB10 Q2TB10 ZNF800 Zinc finger protein 800 1 S(0.252)T(0.697)S(0.051)PS(0.001)AAGGQQK 130.15 0.00037728 7799500.0 35625.0 41893.0 41216.0 44743.0 48151.0 48874.0 40789.0 41985.0 44139.0 44055.0 True False 46953.00895396732 55434.09298773437 40669.448909944025 34428.19262245904 41466.064796760234 45817.90105385253 44419.14198123677 35497.18296932027 46472.09742844553 42512.647859298406 1.1044480012010758 1.3039435504276589 0.9566435157025573 0.8098341165764126 0.9753818424577555 1.0777475259949305 1.0448453393975405 0.8349793474827348 1.0931358023676032 1.0 15.375604498195136 -5.275103036713611 24.888098906938463 0.9685889410449956 1.2041957728977648 0.464587610987785 0.0986772072629418 544.2906260626141 991415.4137083777 0.025991655941224087 0.05458851329924171 5.307585064114812e-06 5.275103036713611 0.2356068318527692 ST(ph)SPSAAGGQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSPSAAGGQQK 12 0 Q2TB10 Q2TB10 ZNF800 Zinc finger protein 800 1 S(0.083)T(0.869)S(0.049)PSAAGGQQK 158.34 6.0806e-12 0.0 44774.0 55894.0 59844.0 41458.0 72063.0 43617.0 37801.0 36562.0 43410.0 39282.0 True False 52353.35387319017 61442.78692942279 61270.907919633806 39135.242668649465 57942.77245857387 41329.64773665985 34220.21562445974 35602.28624064115 44044.78912634846 46403.515643859115 1.1282195572205194 1.3240976696892561 1.3203936613311795 0.8433680535976479 1.248672038198076 0.890657683220803 0.7374487719227009 0.7672325199212064 0.9491692281331965 1.0 15.501946491148473 -6.351888626241919 0.9791607937533445 0.8436764659694018 1.2493637605317949 0.47124209268428907 0.15318316447655791 0.45395708880934776 0.9298180233103389 0.0747129752644789 0.10592142154969081 4.4474530669249033e-07 6.351888626241919 0.40568729456239305 ST(ph)SPSAAGGQQK ddPTM_PC-9_Lapatinib_30min_R1 2 STSPSAAGGQQK 12 0 Q2TB10 Q2TB10 ZNF800 Zinc finger protein 800 1 S(0.137)T(0.79)S(0.072)PSAAGGQQK;S(0.023)T(0.766)S(0.21)PSAAGGQQK 124.38 0.00079267 17822200.0 57921.0 76343.0 63383.0 58907.0 76188.0 60089.0 80658.0 65462.0 77276.0 57012.0 True False 57095.03591858945 76166.23247399999 58171.89440545539 63239.21728799137 71706.77163137116 57519.133544300465 84834.07657737502 68503.60350078021 68572.36312764478 66866.44823628518 0.8538667362267155 1.1390799793171646 0.8699713524471053 0.9457540957540274 1.072387924329131 0.8602091940197837 1.268709177996083 1.0244839573160793 1.0255122701497683 1.0 16.028994866869994 -7.231181974653333 24.999895320805 1.0817168414450256 0.9659546178793558 0.22521406015044398 0.11079054633001952 1085.968533437878 897272.7180529572 0.040510347057315994 0.03137477150499723 5.87243238934198e-08 7.231181974653333 -0.11576222356566979 ST(ph)SPTFNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSPTFNK 8 0 Q9BX63 Q9BX63 BRIP1 Fanconi anemia group J protein 1 S(0.324)T(0.337)S(0.337)PT(0.002)FNK 83.948 0.035072000000000006 7599200.0 84355.0 69692.0 78507.0 89377.0 91699.0 90120.0 96669.0 74875.0 88593.0 64961.0 True False 98634.63541280545 76610.56118161754 80378.90461945557 84369.49645414346 73731.23921677953 85393.9485528071 87511.81249704763 72909.61058662037 89888.50502351053 76737.91506900694 1.2853442177065637 0.99834040464515 1.047447074202817 1.0994499443759163 0.9608189009367321 1.1127999565275677 1.1403986206603636 0.9501119560136089 1.1713701752605328 1.0 16.227651947715778 -4.752756247451867 24.999439834344603 1.0547886725081168 1.2853446536737136 0.4805622789921238 0.07232558540055536 281.3770515108588 810046.8072120255 0.01688751942830907 0.1951762044800262 1.767029307025945e-05 4.752756247451867 0.23055598116559683 ST(ph)SQGSINSPVYSR ddPTM_PC-9_AZD4547_30min_R2 1 STSQGSINSPVYSR 14 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4;H0Y7N6;F6XFR5 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 S(0.001)T(0.499)S(0.499)QGSINSPVYSR 224.06 5.9057e-20 35421000.0 74303.0 82239.0 134510.0 189010.0 155940.0 133790.0 129020.0 196270.0 137200.0 136870.0 True False 97929.8084015896 108821.1484787026 132726.30951272737 145436.66467539014 134290.4227203337 125424.09015007855 140502.53005514186 165940.9813359177 144452.11190064857 132078.22295998555 0.7414531041295009 0.8239143898208797 1.0049068388279132 1.101140380420258 1.0167491635696702 0.9496197581949377 1.0637827107782072 1.2563841155418272 1.0936860646922226 1.0 17.011033089261076 -5.22770281100345 2.0739830560438244 1.0730235304562912 0.7391107376608423 0.6873384358107392 0.07692003291521174 0.22680020085953637 1.7504320269745244 0.023870387456624415 0.09873953363712944 5.919665800858134e-06 5.22770281100345 -0.33391279279544883 ST(ph)SQGSINSPVYSR ddPTM_PC-9_Lapatinib_30min_R1 1 STSQGSINSPVYSR 14 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4;H0Y7N6;F6XFR5 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 S(0.008)T(0.591)S(0.399)QGS(0.002)INSPVYSR 168.5 0.00085461 4480100.0 22176.0 19890.0 24706.0 15927.0 23214.0 19276.0 21760.0 17795.0 25988.0 22744.0 True False 21859.76617341967 19843.94592703795 22674.768047917914 17098.324710914487 21848.598160479996 18451.61041455068 22886.6263275023 18621.820663841365 23060.957774227845 26675.270095524967 0.819476844850649 0.7439079662914814 0.8500295579658188 0.6409803780687077 0.8190581794388394 0.6917122244114077 0.8579716810943089 0.6980930501230559 0.8645070018652423 1.0 14.70321525841552 -8.549848248233317 4.985657609955093 0.9999214035249184 0.7659924895383559 0.5310560471201079 0.06892039566461959 0.12849782342349284 13.059486905279902 0.06024066467348221 0.01567042196261129 2.819367906525131e-09 8.549848248233317 -0.23392891398656257 ST(ph)TPPPAEPVSLPQEPPKPR ddPTM_PC-9_Lapatinib_30min_R1 1 STTPPPAEPVSLPQEPPKPR 20 1 Q9UN86-2 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 S(0.288)T(0.356)T(0.356)PPPAEPVSLPQEPPKPR 87.74799999999999 0.0019898 0.0 12655.0 24353.0 10653.0 12177.0 10615.0 10975.0 7949.0 9386.6 8411.9 7157.2 True False 12474.537379357225 24296.61212474386 9777.151461769197 13072.537201281202 9990.646569892959 10505.62483397457 8360.560325244282 9822.73570346802 7464.463240766018 8394.312483630461 1.4860701699732417 2.8944135892158025 1.164735227671757 1.557308859632475 1.1901685324885711 1.2515170068378234 0.9959791634571623 1.1701655999372302 0.8892286599197112 1.0 13.03519645412762 -5.290761233541481 24.801568031952716 1.17223017051081 2.190241815990124 0.5719451942797615 0.358815751173875 361.1420731637891 305467.4710954088 0.08760019346476126 0.18239798582778885 5.119632253691012e-06 5.290761233541481 1.0180116454793138 ST(ph)TPTSSPFR ddPTM_PC-9_Lapatinib_30min_R1 2 STTPTSSPFR 10 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;H7C5N8;A0A2R8Y7F4;A0A2R8YET2;A0A2R8Y424 E7EPN9 PRRC2C Protein PRRC2C 1 S(0.208)T(0.723)T(0.068)PTSSPFR;S(0.288)T(0.423)T(0.288)PTSSPFR 128.51 0.00067752 55885000.0 121825.0 117125.0 128194.0 103848.0 110745.0 106603.0 86302.0 89185.0 112707.0 85029.0 True False 120087.75316003109 116853.80425863866 117654.38416315021 111485.32834677242 104231.19683304732 102043.83819373048 90770.29528107087 93328.86068584974 100012.75080267423 99726.14935597908 1.2041751730668946 1.1717468789607155 1.179774662141773 1.11791470007348 1.0451741845660476 1.023240532726058 0.9101955291290782 0.9358514420596568 1.0028738846184877 1.0 16.605684225193208 -6.344377378166924 1.17934023273791 0.9586232494724689 1.191296277763906 0.9062562228715707 0.03019436656889935 0.1301604580478444 0.3750390222346179 0.013228604982785221 0.01787862785680847 4.525042075956193e-07 6.344377378166924 0.2326730282914371 ST(ph)VLGLPQHVQK ddPTM_PC-9_AZD4547_30min_R2 1 STVLGLPQHVQK 12 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 S(0.21)T(0.79)VLGLPQHVQK 143.56 0.00017993 52740000.0 150540.0 164850.0 214180.0 250240.0 216830.0 245070.0 199430.0 266240.0 253370.0 255280.0 True False 198408.58857347994 218134.5386825485 211339.83325727415 192551.03416945974 186726.89725824047 229745.73415860522 217178.88365289767 225098.72558656253 266762.62093489297 246342.7249011845 0.8054168786720518 0.8854921076725478 0.8579097813505511 0.7816388092918019 0.7579963943856766 0.9326264221960002 0.8816127358338456 0.9137624245930397 1.0828922227839264 1.0 17.91030734042844 -7.834703121409025 1.23486176407392 1.0378186740030335 0.8308924877522844 0.680350254871215 0.05337664719064904 0.2848700694212747 0.7849655901263461 0.04764899890204924 0.017788942818565884 1.4631770432561458e-08 7.834703121409025 -0.2069261862507491 ST(ph)VLGLPQHVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STVLGLPQHVQK 12 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 S(0.016)T(0.984)VLGLPQHVQK 105.19 0.0038176 32274000.0 101480.0 93447.0 108640.0 103530.0 124430.0 92065.0 82697.0 98326.0 78219.0 74963.0 True False 118658.55967863786 102723.80059029192 111230.3896194945 97729.54974878853 100048.83472822877 87236.94932883019 74863.34148556778 95745.0466850087 79362.8048991905 88553.19849321856 1.3399692128311411 1.1600236054506665 1.2560855114455585 1.1036252943056901 1.1298161605748274 0.9851360629905518 0.8454052790797935 1.081215001989351 0.8962161305248407 1.0 16.434256796825544 -6.26079150875071 1.0017358538787038 0.9538959031598149 1.2609455330742934 0.7206117211473434 0.07700567122209914 0.28943780385787643 0.6126247909044658 0.03439405539584857 0.05360873966487483 5.48540238798583e-07 6.26079150875071 0.3070496299144785 STAALSGEAASCS(ph)PIIMPYK ddPTM_PC-9_AZD4547_30min_R2 1 STAALSGEAASCSPIIMPYK 20 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;Q14244-2;Q14244-4 Q14244-5 MAP7 Ensconsin 1 STAALSGEAAS(0.023)CS(0.977)PIIMPYK 162.82 4.1515e-21 0.0 9563.7 9683.1 11115.0 15435.0 12150.0 12845.0 10748.0 17644.0 13994.0 12736.0 True False 12604.75766268231 12812.972711659004 10967.60783758801 11876.69921837282 10463.182224266104 12041.80011942415 11704.551178365065 14917.525218784971 14733.694270682767 12290.116516536704 1.0256011524156217 1.0425428184036158 0.8923925027749557 0.9663618080749992 0.8513493106584947 0.9797954399554767 0.9523547773217819 1.213782245165293 1.19882462065011 1.0 13.585210972805415 -7.751528485884693 24.999099463846807 1.1547275741907799 0.9562936362593976 0.5360250919171947 0.07575023453008739 134.68074925094652 339718.9811204237 0.036044428858546404 0.02048899679752896 1.7720318116772877e-08 7.751528485884693 -0.1984339379313823 STADS(ph)GGEGLETAPK ddPTM_PC-9_AZD4547_30min_R2 4 STADSGGEGLETAPK 15 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 STADS(1)GGEGLETAPK;STADS(1)GGEGLETAPK;ST(0.001)ADS(0.998)GGEGLETAPK;S(0.132)T(0.176)ADS(0.692)GGEGLETAPK 179.97 2.5560999999999998e-05 22216900.0 98686.0 81568.0 111992.0 141733.0 125887.0 107717.0 97909.0 116278.0 87736.0 118680.0 True False 130066.09520368313 107933.2608508228 110506.91290572725 109058.64660302136 108409.76301779323 100981.43896177568 106622.71132513449 98309.90690262272 92373.54584340609 114525.04932338033 1.1356999710728795 0.9424423869581184 0.9649147811645362 0.9522689337166432 0.9466030676981454 0.8817410650192166 0.9309990430483702 0.8584140105893211 0.8065794024028243 1.0 16.80530365862939 -1.5228787452803778 0.6355896220496797 0.898271001567631 18.11663032757093 0.5897982535231706 0.05381971686474219 144.50864684741632 0.9844882800853424 0.022995344246511396 3489.120737554347 0.02999999999999722 1.5228787452803778 17.2183593260033 STADS(ph)GGEGLETAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STADSGGEGLETAPK 15 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 S(0.001)T(0.001)ADS(0.997)GGEGLET(0.002)APK;S(0.002)T(0.001)ADS(0.981)GGEGLET(0.016)APK;S(0.238)T(0.137)ADS(0.625)GGEGLETAPK;S(0.001)T(0.001)ADS(0.902)GGEGLET(0.095)APK 109.1 0.00066544 9136200.0 56880.0 57600.0 56084.0 80586.0 79945.0 75496.0 79726.0 89140.0 61882.0 58046.0 True False 66508.66056879117 63318.147334861584 57421.255259754405 76071.02768333722 64280.35113998443 71536.8568568877 72173.77611374513 86800.16945163721 62786.90718075783 68569.28030811693 0.9699483539849574 0.9234185782662541 0.837419541254207 1.1094039100528852 0.9374511567153667 1.0432785138685419 1.0525672107018094 1.2658754629128315 0.9156710832988777 1.0 16.065274759542937 -6.2768787861296245 1.002377504701438 1.0734755094323376 0.9209782042949076 0.18621354669759338 0.1033354354008349 0.7858190082210277 1.6681126914191098 0.04687030546392442 0.07171273356185015 5.285927642046012e-07 6.2768787861296245 -0.15249730513742998 STADS(ph)GGEGLETAPK ddPTM_PC-9_Lapatinib_30min_R1 2 STADSGGEGLETAPK 15 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 STADS(1)GGEGLETAPK;S(0.015)T(0.037)ADS(0.887)GGEGLET(0.062)APK 182.1 8.8334e-06 11182300.0 37629.0 43084.0 54215.0 50354.0 51914.0 51346.0 46670.0 44786.0 46628.0 46460.0 True False 37092.403559686514 42984.241645073045 49757.65197595198 54057.201136019794 48860.52058685098 49150.051273372024 49086.344241936196 46866.92105933125 41376.26362539236 54490.54909594134 0.6807126038384755 0.788838474895726 0.9131427890062888 0.992047282196431 0.8966788075639028 0.9019922186292101 0.9008230795309115 0.8600926552751893 0.7593291738084949 1.0 15.733718408434163 -4.990113487317713 2.7299067028671926 0.9005453975550285 0.6781807294764267 0.5562391210597742 0.06358236024383959 0.2410750926698839 3.2236277624997296 0.01727174000225593 0.0983751905776149 1.0230256262197565e-05 4.990113487317713 -0.22236466807860178 STAGDTHLGGEDFDNR ddPTM_PC-9_AZD4547_30min_R2 5 STAGDTHLGGEDFDNR 16 0 P11142;E9PKE3;P11142-2;E9PN89;P54652 P11142 HSPA8;HSPA2 Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2 0 ;;;; 297.5 3.676699999999999e-111 389634000.0 347621.4 313332.6 630132.0 883561.0 732030.0 650223.0 542025.0 754792.0 548060.0 645631.0 False True 458157.7742257024 414611.23539704876 621776.037959065 679869.6623313713 630400.2702575746 609564.4530208136 590264.1749584426 638156.2397946696 577029.3327133349 623027.6552047826 0.7353730936311499 0.6654780601364645 0.997991072731264 1.0912351268065386 1.0118335277594839 0.9783906828669688 0.9474124784467697 1.02428236445606 0.9261696939017442 1.0 19.248936678041268 -5.265720999293968 24.832617232154266 0.9994678315924002 0.7004255620944445 0.8747765599692262 0.04490173461066096 94.26882385894665 546745.5358217843 0.012097009305297994 0.026674943792387374 5.423491960351316e-06 5.265720999293968 -0.29904226949795565 STAGDTHLGGEDFDNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 9 STAGDTHLGGEDFDNR 16 0 P11142;E9PKE3;P11142-2;E9PN89;P54652 P11142 HSPA8;HSPA2 Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2 0 ;;;;;;;; 213.99 2.9661e-21 497235000.0 526441.2 540705.5 815136.0 872430.0 936916.0 853494.0 828293.0 782375.0 784211.6 610843.0 False True 615557.2974723488 594383.1686418407 834571.933660493 823550.575556223 753334.0355077822 808735.2721496844 749831.0907179858 761838.4852448337 795679.2110674097 721584.0004694739 0.8530639496882657 0.823719994145 1.156583201841376 1.14130936248643 1.0440004698242358 1.120777721822419 1.0391459486769854 1.0557862767871373 1.1026841096112556 1.0 19.46080782481053 -5.25328281257489 24.98834921069389 1.0850671811107924 0.83839193692774 0.8112119982907935 0.04709872378684377 232.58937196045812 712553.4965208727 0.011990034624175477 0.030575979409232158 5.5810663732252325e-06 5.25328281257489 -0.24667524418305242 STAGDTHLGGEDFDNR ddPTM_PC-9_Lapatinib_30min_R1 5 STAGDTHLGGEDFDNR 16 0 P11142;E9PKE3;P11142-2;E9PN89;P54652 P11142 HSPA8;HSPA2 Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2 0 ;;;; 166.79 4.907e-06 575546000.0 961441.0 771158.0 1143927.0 844850.0 942232.0 1003413.0 807440.0 903400.0 1146126.0 784762.0 False True 947730.6750333156 769372.4310308072 1049877.7377459174 906983.0873369809 886811.7662593871 960499.3650599467 849245.2923657373 945375.262023845 1017037.2206381677 920407.0660703627 1.0296864398049548 0.8359045246312686 1.1406667511021227 0.9854151720165568 0.9634995198869896 1.043559312468945 0.9226844552503844 1.027127340579949 1.1049863241276092 1.0 19.811912533776237 -7.995607237724458 24.89028123464332 1.0570143983715992 0.9886823404635293 0.09931286806851913 0.07854021726758094 232.38892617891432 1316761.1557496646 0.041367830398210424 0.019743936920724764 1.010166035506283e-08 7.995607237724458 -0.06833205790806984 STAPETAIECTQAPAPAS(ph)EDEKVVVEPPEGEEKVEK ddPTM_PC-9_AZD4547_30min_R2 1 STAPETAIECTQAPAPASEDEKVVVEPPEGEEKVEK 36 2 Q14839-2;A0A2R8Y8C1;A0A0C4DGG9;A0A2R8Y521;A0A2R8Y212;F5GWX5;A0A2U3TZM0;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8YER1;Q14839;A0A2R8YDJ9;A0A2R8YD40;A0A2R8YE38;A0A2R8YDW2;A0A2R8YFD8;A0A2R8Y5M9;A0A2R8Y4X2;A0A2R8Y7I0;A0A2R8Y7M9;A0A2R8Y6G9 Q14839-2 CHD4 Chromodomain-helicase-DNA-binding protein 4 1 STAPETAIECT(0.029)QAPAPAS(0.971)EDEKVVVEPPEGEEKVEK 105.05 7.7042e-22 12663000.0 61904.0 60986.0 57036.0 75581.0 71916.0 67552.0 65947.0 64923.0 64245.0 75211.0 True False 81588.18431681088 80698.53185376964 56279.66537333964 58156.968164809616 61931.70476052022 63327.96276117864 71816.15524373284 54890.64213212293 67640.85954123299 72577.88578244674 1.1241466107372242 1.1118887107798188 0.7754382036153374 0.8013042476758825 0.8533137069624953 0.8725517708108104 0.9895046468975798 0.7562998224646337 0.9319761634278992 1.0 16.147242410800352 -5.247150786408464 24.110516703476566 0.8647907133480457 1.118017762518054 0.6058751328571568 0.07899415633819998 307.5457278221652 518947.5617985411 0.019541332080359554 0.05111518382718259 5.660427257110966e-06 5.247150786408464 0.2532270491700084 STAPETAIECTQAPAPAS(ph)EDEKVVVEPPEGEEKVEK ddPTM_PC-9_Lapatinib_30min_R1 3 STAPETAIECTQAPAPASEDEKVVVEPPEGEEKVEK 36 2 Q14839-2;A0A2R8Y8C1;A0A0C4DGG9;A0A2R8Y521;A0A2R8Y212;F5GWX5;A0A2U3TZM0;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8YER1;Q14839;A0A2R8YDJ9;A0A2R8YD40;A0A2R8YE38;A0A2R8YDW2;A0A2R8YFD8;A0A2R8Y5M9;A0A2R8Y4X2;A0A2R8Y7I0;A0A2R8Y7M9;A0A2R8Y6G9 Q14839-2 CHD4 Chromodomain-helicase-DNA-binding protein 4 1 STAPETAIECT(0.032)QAPAPAS(0.968)EDEKVVVEPPEGEEKVEK;STAPETAIECTQAPAPAS(1)EDEKVVVEPPEGEEKVEK;STAPETAIECT(0.018)QAPAPAS(0.982)EDEKVVVEPPEGEEKVEK 130.21 4.9485e-23 16304200.0 100233.4 97082.0 94754.0 106507.0 105337.0 103827.0 88962.0 95232.0 92419.0 83207.0 True False 98804.05333544569 96857.21259370008 86963.6918810174 114339.88007693632 99141.28476051008 99386.56124255821 93568.01706559086 99656.82638150848 82009.7990047854 97589.21908364192 1.0124484473101742 0.992499104954263 0.8911198664934743 1.171644584827938 1.0159040690297758 1.0184174253651503 0.9587946080949314 1.021186841305641 0.8403571600926155 1.0 16.574434158140328 -8.226399686938397 24.909042338794915 0.9201784936341206 1.0098141599184944 0.18770147744360755 0.07494700225473098 828.0477571843223 588644.8091080977 0.04973894561185449 0.018798007421183212 5.937454753040495e-09 8.226399686938397 0.0896356662843738 STAPSAAASASASAAAS(ph)SPAGGGAEALELLEHCGVCR ddPTM_PC-9_AZD4547_30min_R2 3 STAPSAAASASASAAASSPAGGGAEALELLEHCGVCR 37 0 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 STAPSAAASASASAAAS(0.55)S(0.449)PAGGGAEALELLEHCGVCR;STAPSAAAS(0.115)AS(0.098)AS(0.09)AAAS(0.349)S(0.349)PAGGGAEALELLEHCGVCR;STAPSAAASASAS(0.003)AAAS(0.499)S(0.499)PAGGGAEALELLEHCGVCR 152.01 1.1662999999999998e-26 84863400.0 49654.0 50435.0 76410.0 101855.0 89928.0 85564.0 70519.0 86528.0 69215.0 80210.0 True False 65442.93913263981 66737.12743982006 75396.75347459287 78373.90339406306 77443.04947027177 80213.66955378804 76795.05438659544 73157.08581563279 72873.5635947769 77401.87231402397 0.8454955568404591 0.8622159315353973 0.9740946984939044 1.012558237300714 1.0005319917337494 1.0363272509527475 0.9921601647442502 0.9451591237848894 0.9414961346041417 1.0 16.24008084443964 -5.26579246118208 3.712531990926305 0.9902480107165889 0.8486904753603187 0.7998528334444567 0.026950420079557193 0.10057587416092795 3.1045868585239305 0.00809747809238696 0.021544370105595314 5.422599614013649e-06 5.26579246118208 -0.14155753535627014 STAPSAAASASASAAAS(ph)SPAGGGAEALELLEHCGVCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 STAPSAAASASASAAASSPAGGGAEALELLEHCGVCR 37 0 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 STAPSAAASASASAAAS(0.5)S(0.5)PAGGGAEALELLEHCGVCR;STAPSAAASASASAAAS(0.565)S(0.435)PAGGGAEALELLEHCGVCR;STAPSAAASASASAAAS(0.5)S(0.5)PAGGGAEALELLEHCGVCR;STAPSAAASASASAAAS(0.5)S(0.5)PAGGGAEALELLEHCGVCR;STAPSAAASASASAAAS(0.555)S(0.445)PAGGGAEALELLEHCGVCR 175.75 2.608e-31 278876700.0 85126.6 82663.5 97921.9 104357.7 110933.9 86634.9 100143.5 92101.9 91520.4 75839.7 True False 99536.852053011 90869.78597596053 100256.72946687385 98510.87640122809 89197.19864066454 82091.61333197486 90657.18270384592 89684.32271502954 92858.71271041359 89588.83726326494 1.1110407846963446 1.0142980839111844 1.1190761319098308 1.0995887368394448 0.995628488609027 0.9163151999700722 1.0119249838843376 1.0010658186296582 1.0364986927728488 1.0 16.451031363749834 -6.2705397201698005 22.357998361551097 0.9906802523958026 1.0832418168644102 0.5704657885123021 0.039213994069237444 117.9202372952005 289709.3551311631 0.012424695362893144 0.014331796932826052 5.363648137694294e-07 6.2705397201698005 0.09256156446860764 STAPSAAASASASAAAS(ph)SPAGGGAEALELLEHCGVCR ddPTM_PC-9_Lapatinib_30min_R1 6 STAPSAAASASASAAASSPAGGGAEALELLEHCGVCR 37 0 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 STAPSAAASASASAAAS(0.5)S(0.5)PAGGGAEALELLEHCGVCR;STAPSAAAS(0.147)AS(0.134)AS(0.112)AAAS(0.303)S(0.303)PAGGGAEALELLEHCGVCR;STAPSAAASASASAAAS(0.5)S(0.5)PAGGGAEALELLEHCGVCR;STAPSAAASASASAAAS(0.5)S(0.5)PAGGGAEALELLEHCGVCR;STAPSAAAS(0.005)AS(0.005)AS(0.028)AAAS(0.481)S(0.481)PAGGGAEALELLEHCGVCR;STAPSAAASASASAAAS(0.563)S(0.437)PAGGGAEALELLEHCGVCR 167.41 3.601699999999999e-27 84227800.0 52476.600000000006 60100.5 64999.1 58087.5 65533.7 68529.5 59491.0 57201.5 70619.1 52798.3 True False 51728.27406097015 59961.340984813745 59655.12490178185 62359.44852421958 61679.13661021145 65598.65303506702 62571.1528883014 59859.290514342385 62665.23330590942 61924.41580568751 0.8353453704478729 0.9682988560274239 0.9633538585002326 1.007025221197034 0.9960390551564391 1.059334225144875 1.0104439755175614 0.9666508716396247 1.0119632537599794 1.0 15.918220732714861 -3.8368773925697495 1.0174309043993803 1.0069716869673013 1.163834310734225e-15 0.8137306373219205 0.024073685468089735 4.5242399278420855 0.8937245696173919 0.00794354986542325 7.821133894133209 0.0001455870035123174 3.8368773925697495 -1.0069716869673002 STAPSAAASASASAAASS(ph)PAGGGAEALELLEHCGVCR ddPTM_PC-9_AZD4547_30min_R2 5 STAPSAAASASASAAASSPAGGGAEALELLEHCGVCR 37 0 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 STAPSAAASASASAAAS(0.204)S(0.796)PAGGGAEALELLEHCGVCR;STAPSAAASASASAAAS(0.187)S(0.813)PAGGGAEALELLEHCGVCR;STAPSAAASASASAAAS(0.208)S(0.792)PAGGGAEALELLEHCGVCR;STAPSAAASASASAAAS(0.204)S(0.796)PAGGGAEALELLEHCGVCR;STAPSAAAS(0.004)AS(0.03)AS(0.086)AAAS(0.219)S(0.662)PAGGGAEALELLEHCGVCR 203.29 7.2351e-55 862901400.0 93340.6 97720.1 132080.0 214406.0 165553.0 153744.0 116890.0 159102.0 119175.0 143068.0 True False 123020.96919491055 129306.21130429205 130328.53290046105 164978.00923967903 142568.82360279237 144130.36337569103 127292.98355406531 134516.44170024502 125474.34719941553 138059.23286651025 0.8910738285345955 0.936599520506669 0.944004469635696 1.1949799069157265 1.0326641735047337 1.0439748243063973 0.9220171727098119 0.974338614718432 0.9088443025084525 1.0 17.07492784744295 -10.565808700449868 14.679270086608707 0.9999851816764888 0.9880608928080453 0.0005415894597825543 0.08529500158903086 0.0 0.0 0.08835443416143766 0.02142909791407582 2.7176360790634215e-11 10.565808700449868 -0.011924288868443433 STAPSAAASASASAAASS(ph)PAGGGAEALELLEHCGVCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 STAPSAAASASASAAASSPAGGGAEALELLEHCGVCR 37 0 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 STAPSAAASASASAAAS(0.205)S(0.795)PAGGGAEALELLEHCGVCR;STAPSAAASASASAAAS(0.357)S(0.643)PAGGGAEALELLEHCGVCR;STAPSAAASASAS(0.001)AAAS(0.234)S(0.765)PAGGGAEALELLEHCGVCR;STAPSAAASASASAAAS(0.097)S(0.903)PAGGGAEALELLEHCGVCR;STAPSAAASASAS(0.001)AAAS(0.216)S(0.783)PAGGGAEALELLEHCGVCR 184.28 1.7975999999999999e-37 268239100.0 76764.9 70134.5 103016.4 100492.8 121008.1 100375.7 101536.20000000001 90492.7 95934.59999999999 80585.0 True False 89759.68139411396 77096.98965723706 105472.70166787281 94862.51421805363 97297.4314689143 95111.821590679 91917.95607757126 88117.36250994114 97337.46203456807 95194.4225894912 0.9429090376564015 0.8098897767330755 1.1079714420108921 0.9965133632579626 1.0220917236768372 0.9991322916136758 0.9655813184975226 0.9256567781279729 1.0225122374481785 1.0 16.53858942852176 -5.2497218796658975 24.995872356951264 1.000976892855702 0.8763994126467557 0.4830454952040125 0.05306106140648659 643.9537849267616 1373682.042792932 0.013420333507124809 0.034908566979851306 5.627015615114099e-06 5.2497218796658975 -0.12457748020894621 STAPSAAASASASAAASS(ph)PAGGGAEALELLEHCGVCR ddPTM_PC-9_Lapatinib_30min_R1 3 STAPSAAASASASAAASSPAGGGAEALELLEHCGVCR 37 0 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 STAPSAAASASASAAAS(0.317)S(0.683)PAGGGAEALELLEHCGVCR;STAPSAAASASAS(0.001)AAAS(0.496)S(0.503)PAGGGAEALELLEHCGVCR;STAPSAAASASASAAAS(0.042)S(0.958)PAGGGAEALELLEHCGVCR 189.35 7.606699999999999e-38 639752000.0 146706.0 171474.0 235665.0 165642.0 202556.0 200322.0 184212.0 174405.0 207066.0 152931.0 True False 144613.94553741478 171076.96248833142 216289.53339320683 177823.86524551408 190642.05432041836 191754.69503339 193749.59600376143 182508.49299675468 183744.04657835411 179364.91958225158 0.8062554588390346 0.9537927644200263 1.2058630745463172 0.9914082734777421 1.062872577115033 1.0690758007752839 1.0801978249426496 1.0175261328794092 1.0244146235858256 1.0 17.452538228163256 -4.928327234004823 4.07109208546938 1.0577311285283972 0.8149116263155677 0.6371477030520899 0.05831372716906246 0.13038414132697126 4.051344636105473 0.014149344862683235 0.06997480057675638 1.1794316177434765e-05 4.928327234004823 -0.24281950221282955 STAQQELDGKPAS(ph)PTPVIVASHTANK ddPTM_PC-9_AZD4547_30min_R2 4 STAQQELDGKPASPTPVIVASHTANK 26 1 H0YAC7;P35606-2;P35606 H0YAC7 COPB2 Coatomer subunit beta 1 STAQQELDGKPAS(0.5)PT(0.5)PVIVASHTANK;STAQQELDGKPAS(0.913)PT(0.087)PVIVASHTANK;STAQQELDGKPAS(0.921)PT(0.079)PVIVASHTANK;STAQQELDGKPAS(0.907)PT(0.091)PVIVAS(0.001)HTANK 104.81 4.2655999999999997e-10 222012000.0 296422.0 365148.0 346507.0 259336.0 275734.0 392294.0 432474.0 413985.0 405858.0 349535.0 True False 390678.0300393796 483174.9501416764 341912.09077634814 199550.0919012593 237453.09361529158 367763.79416499595 470963.34818684973 350013.1306789104 427310.82530447165 337297.8860401742 1.158258163506093 1.432487335791151 1.0136799100354408 0.5916138231518346 0.7039863083725626 1.0903234481617625 1.396283130368493 1.037697374235016 1.2668648188728238 1.0 18.363663750963873 -6.997291777480098 24.984312093727326 1.1876314423123588 0.9766083762645372 0.1286708097014282 0.23921525979612984 189.40956547938222 1747348.131470997 0.09533541329121796 0.08360806157867769 1.0062553965857489e-07 6.997291777480098 -0.21102306604782162 STAQQELDGKPAS(ph)PTPVIVASHTANK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STAQQELDGKPASPTPVIVASHTANK 26 1 H0YAC7;P35606-2;P35606 H0YAC7 COPB2 Coatomer subunit beta 1 S(0.001)T(0.001)AQQELDGKPAS(0.71)PT(0.289)PVIVASHTANK;S(0.001)T(0.001)AQQELDGKPAS(0.831)PT(0.154)PVIVAS(0.012)HT(0.001)ANK;STAQQELDGKPAS(0.5)PT(0.5)PVIVASHTANK;S(0.006)T(0.006)AQQELDGKPAS(0.64)PT(0.343)PVIVAS(0.004)HT(0.001)ANK 88.709 3.3195e-07 232777000.0 259964.0 407654.0 277725.0 286706.0 303748.0 203304.0 317441.0 185461.4 203834.3 219873.0 True False 303970.7706769558 448123.1950285711 284347.0172779282 270642.792333393 244230.7598732629 192642.38034376263 287370.690406183 180593.23476259675 206814.9910208906 259734.23438629013 1.1703146156115671 1.7253143240336166 1.0947614123713574 1.0419989223710846 0.9403102384648699 0.7416903697694889 1.106402823968097 0.6953000831380941 0.7962561866731233 1.0 17.98667665604753 -5.62071460495119 2.1061199131336097 0.8803436809018824 1.4468552163478268 0.5826860042436672 0.17949427647840718 0.20130267272915442 1.7925353825768002 0.05051085397862351 0.11314693784577352 2.3948890320824775e-06 5.62071460495119 0.5665115354459443 STAQQELDGKPAS(ph)PTPVIVASHTANK ddPTM_PC-9_Lapatinib_30min_R1 2 STAQQELDGKPASPTPVIVASHTANK 26 1 H0YAC7;P35606-2;P35606 H0YAC7 COPB2 Coatomer subunit beta 1 STAQQELDGKPAS(0.762)PT(0.238)PVIVASHTANK;STAQQELDGKPAS(0.957)PT(0.043)PVIVASHTANK 125.37 3.622e-11 91651000.0 167957.0 195033.0 168956.0 151243.0 191136.0 191135.0 194397.0 203832.0 177998.0 161200.0 True False 165561.90238045872 194581.4130712921 155065.08986902077 162365.91475185775 179893.75626783422 182960.60160744688 204461.92546817384 213302.77884529982 157949.99083796394 189063.20521450127 0.8756960519770137 1.0291871062406361 0.8201759284314046 0.8587917176567795 0.9515006162290337 0.967721886444638 1.0814474727443766 1.1282088368453163 0.8354348518463024 1.0 17.528509093040682 -6.764570539779412 2.460885442775251 1.0206780807845717 0.9017379617346961 0.2406339448998598 0.0878840551476746 0.3965771114241203 4.925523779696645 0.03359849424741839 0.031022167678255313 1.7196080132094857e-07 6.764570539779412 -0.11894011904987556 STAQQELDGKPAS(ph)PTPVIVASHTANKEEK ddPTM_PC-9_AZD4547_30min_R2 8 STAQQELDGKPASPTPVIVASHTANKEEK 29 2 H0YAC7;P35606-2;P35606 H0YAC7 COPB2 Coatomer subunit beta 1 STAQQELDGKPAS(0.5)PT(0.5)PVIVASHTANKEEK;STAQQELDGKPAS(0.844)PT(0.146)PVIVAS(0.01)HTANKEEK;STAQQELDGKPAS(0.5)PT(0.5)PVIVASHTANKEEK;STAQQELDGKPAS(0.604)PT(0.395)PVIVAS(0.001)HTANKEEK;S(0.001)T(0.001)AQQELDGKPAS(0.753)PT(0.238)PVIVAS(0.006)HTANKEEK;STAQQELDGKPAS(0.839)PT(0.161)PVIVASHTANKEEK;STAQQELDGKPAS(0.829)PT(0.171)PVIVASHTANKEEK;STAQQELDGKPAS(0.702)PT(0.266)PVIVAS(0.029)HT(0.003)ANKEEK 111.56 3.1076e-12 515644600.0 1077710.0 976079.0 941815.0 1220524.0 1122013.0 1148725.0 1038418.0 1002140.0 1019944.0 1129795.0 True False 1420399.362239444 1291577.4484848257 929325.9177290114 939151.048707824 966240.8623041569 1076895.044156133 1130835.1903177775 847282.2898862589 1073856.1575830556 1090241.2209328339 1.3028303598942257 1.1846712669511104 0.8524039450038957 0.8614158322726654 0.8862633734187929 0.9877585102081523 1.0372339337437733 0.7771512153625103 0.984971157726215 1.0 20.05621594262133 -5.11967648997941 3.955780608419857 0.9187640323880815 1.2806056240280073 0.7366807847670349 0.07775303019897926 0.10912595801655063 2.878851436279497 0.02037298758939231 0.06427348706693323 7.5914285707396545e-06 5.11967648997941 0.3618415916399258 STAQQELDGKPAS(ph)PTPVIVASHTANKEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 STAQQELDGKPASPTPVIVASHTANKEEK 29 2 H0YAC7;P35606-2;P35606 H0YAC7 COPB2 Coatomer subunit beta 1 STAQQELDGKPAS(0.826)PT(0.174)PVIVASHTANKEEK;STAQQELDGKPAS(0.994)PT(0.006)PVIVASHTANKEEK;STAQQELDGKPAS(0.807)PT(0.193)PVIVASHTANKEEK;STAQQELDGKPAS(0.846)PT(0.154)PVIVASHTANKEEK;STAQQELDGKPAS(0.83)PT(0.17)PVIVASHTANKEEK 154.33 1.2326e-13 563886000.0 1602750.0 1475530.0 1167950.0 1915270.0 1775950.0 1617710.0 1889390.0 1804470.0 1545580.0 1475500.0 True False 1874063.9192445525 1622010.866961949 1195798.3574750435 1807963.6312891238 1427965.346263744 1532874.4397843026 1710413.3012009684 1757104.574494005 1568181.1835499124 1742996.4699484282 1.0751966234905812 0.9305875800253004 0.6860589668953402 1.0372732604229644 0.8192588859953311 0.8794478165693917 0.9813062336560993 1.0080941670214594 0.899704164975338 1.0 20.733138216932893 -7.26637191532468 24.18476566156706 0.9729506613252007 0.8980294579615832 0.08824588472355221 0.10522368611046402 665.2136777854688 3261590.346321529 0.04295999699806076 0.03002329273615814 5.4153693758243964e-08 7.26637191532468 -0.07492120336361752 STAQQELDGKPAS(ph)PTPVIVASHTANKEEK ddPTM_PC-9_Lapatinib_30min_R1 7 STAQQELDGKPASPTPVIVASHTANKEEK 29 2 H0YAC7;P35606-2;P35606 H0YAC7 COPB2 Coatomer subunit beta 1 STAQQELDGKPAS(0.736)PT(0.264)PVIVASHTANKEEK;STAQQELDGKPAS(0.5)PT(0.5)PVIVAS(0.001)HTANKEEK;STAQQELDGKPAS(0.858)PT(0.142)PVIVASHTANKEEK;STAQQELDGKPAS(0.823)PT(0.176)PVIVAS(0.001)HTANKEEK;STAQQELDGKPAS(0.5)PT(0.5)PVIVASHTANKEEK;STAQQELDGKPAS(0.5)PT(0.5)PVIVASHTANKEEK;STAQQELDGKPAS(0.5)PT(0.5)PVIVASHTANKEEK 126.99 1.5973e-12 1143300000.0 1924989.0 1635839.0 1468881.0 1509965.0 1534975.0 1567469.0 1383217.0 1405878.0 1508428.0 1219903.0 True False 1897538.3038602537 1632051.3153011457 1348115.274224631 1621012.8631955774 1444690.7883769635 1500432.0048187044 1454833.2081272386 1471200.224289969 1338532.9541889704 1430761.6081314264 1.3262435146959508 1.1406871040051203 0.9422361255452392 1.1329720157312713 1.0097355004260484 1.048694622703965 1.0168243261903356 1.0282636995071146 0.9355387694090377 1.0 20.44835188120893 -4.886811713450292 2.9548350300598454 1.0207662832748985 1.3449440267438062 0.7655260126531701 0.05330220574822635 0.14275361315246063 2.066771107828915 0.013187342932343638 0.09838820520831056 1.29774177953987e-05 4.886811713450292 0.3241777434689077 STAQQELDGKPASPT(ph)PVIVASHTANK ddPTM_PC-9_AZD4547_30min_R2 1 STAQQELDGKPASPTPVIVASHTANK 26 1 H0YAC7;P35606-2;P35606 H0YAC7 COPB2 Coatomer subunit beta 1 S(0.001)T(0.001)AQQELDGKPAS(0.183)PT(0.814)PVIVAS(0.001)HTANK 60.472 0.001459 101620000.0 32426.0 34810.0 30662.0 31445.0 30589.0 36723.0 34489.0 40974.0 39636.0 33815.0 True False 42736.793497300874 46061.651753348604 30255.401845805092 24195.841070407096 26342.245354574134 34426.7050047188 37558.45418595395 34642.40978885147 41731.07804150225 32631.14714248495 1.3096932605736873 1.4115854264092809 0.9271939387755481 0.7414952641644861 0.8072730400665926 1.0550258884370043 1.1510001172178765 1.0616362838114235 1.2788725403762902 1.0 14.993962085572045 -5.2597508091989935 24.9992628419164 0.9958543463334807 1.3606393719500622 0.4792518482726028 0.14905769511700157 133.51436662068033 1976634.580564048 0.04338371036784595 0.10316144834911935 5.498562815610176e-06 5.2597508091989935 0.36478502561658155 STAQQELDGKPASPT(ph)PVIVASHTANK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STAQQELDGKPASPTPVIVASHTANK 26 1 H0YAC7;P35606-2;P35606 H0YAC7 COPB2 Coatomer subunit beta 1 STAQQELDGKPAS(0.087)PT(0.913)PVIVASHTANK 70.391 0.00016056 163880000.0 58994.0 126020.0 76626.0 79745.0 80381.0 58344.0 85617.0 59835.0 60232.0 58010.0 True False 68980.51901538808 138530.43276283453 78453.05444572338 75277.1461867781 64630.920069836575 55284.337931257985 77506.73794659848 58264.394650422924 61112.77905225112 68526.75379309274 1.0066217235922985 2.0215525337900644 1.1448529239047536 1.0985074006871427 0.9431487191846398 0.8067555351911396 1.1310434780059713 0.8502430280930041 0.8918090478468146 1.0 16.064379725712065 -5.492383922353373 10.858888792852554 0.9667496913367488 1.5316806904814904 0.44163957527218756 0.24626593721228326 0.6296648670395333 221.31698277888958 0.060331866517086476 0.12287942249053474 3.2182225799690843e-06 5.492383922353373 0.5649309991447415 STAQQELDGKPASPT(ph)PVIVASHTANK ddPTM_PC-9_Lapatinib_30min_R1 2 STAQQELDGKPASPTPVIVASHTANK 26 1 H0YAC7;P35606-2;P35606 H0YAC7 COPB2 Coatomer subunit beta 1 S(0.002)T(0.002)AQQELDGKPAS(0.411)PT(0.583)PVIVAS(0.001)HTANK;S(0.009)T(0.009)AQQELDGKPAS(0.379)PT(0.602)PVIVASHTANK 94.72 3.0091999999999995e-09 185638000.0 236356.0 302560.0 242114.0 267968.0 345930.0 292240.0 345270.0 348090.0 277870.0 263080.0 True False 232985.520097618 301859.44090923126 222208.32150706754 287675.2606350432 325583.0775245474 279741.5764447133 363146.3911809149 364263.5321650206 246573.35449918002 308553.0274679352 0.7550906954618355 0.9783065276862354 0.720162506038478 0.9323365354596574 1.0551932683868481 0.9066239885582844 1.176933489069891 1.1805540692770382 0.7991279700692742 1.0 18.235158924559784 -6.008194418943387 5.478295386106142 1.0286505342140182 0.831751337305034 0.3435386956799429 0.12414925991482556 0.19177737476047915 19.47129066481065 0.03577732902936116 0.050156650430866756 9.813085460463375e-07 6.008194418943387 -0.19689919690898416 STAQQELDGKPASPT(ph)PVIVASHTANKEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STAQQELDGKPASPTPVIVASHTANKEEK 29 2 H0YAC7;P35606-2;P35606 H0YAC7 COPB2 Coatomer subunit beta 1 STAQQELDGKPAS(0.174)PT(0.825)PVIVAS(0.002)HTANKEEK;STAQQELDGKPAS(0.191)PT(0.809)PVIVASHTANKEEK 98.96700000000001 4.5736000000000006e-11 92055000.0 347078.0 335138.0 254865.0 399082.0 400400.0 362879.0 404680.0 366404.0 353597.0 338262.0 True False 405831.45029702806 368408.2857901194 260941.94818089454 376722.7293813014 321944.49429545057 343848.98642802954 366345.7807705184 356786.28323712805 358767.6871851971 399586.2229194807 1.0156292359929682 0.9219744442098948 0.6530303929759763 0.9427820774922301 0.8056946807205726 0.860512617066173 0.9168128422794485 0.8928893509649928 0.897847990263396 1.0 18.608147316655263 -8.906940271556415 0.6805927603316274 1.000962234653656 0.8637056925298727 0.14415959175294235 0.09092827529591324 2.6843771036311193 2.3088212400864068 0.1008105261441357 0.03549353439842478 1.2389669697227876e-09 8.906940271556415 -0.13725654212378324 STATT(ph)GSRCRSVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STATTGSRCRSVR 13 2 R4GMV4 R4GMV4 DPP7 1 S(0.037)T(0.21)AT(0.325)T(0.404)GS(0.023)RCRSVR 53.981 0.039434 7598200.0 5095.9 2414.9 5434.4 8929.9 12318.0 14141.0 6669.4 13481.0 11424.0 8755.6 True False 5958.5352213871865 2654.635312481896 5563.97670607677 8429.586654126415 9904.376325502877 13399.421066192226 6037.626149725446 13127.138034300197 11591.054387915336 10342.92097070853 0.5760979164649852 0.2566620512715803 0.5379502291310282 0.815010254646561 0.9575995362966009 1.2955161413434173 0.5837447822355202 1.2691905963002768 1.1206751381685656 1.0 13.33635605793408 -5.8803952752493664 1.9397333841122926 1.043176398031307 0.40763466340352983 0.6349707183802531 0.19830846234245966 0.20476320807096676 1.569610998306631 0.06147378749488881 0.10951229649516778 1.3170574665749644e-06 5.8803952752493664 -0.6355417346277771 STAVTTS(ph)SAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STAVTTSSAK 10 0 Q9UKM9-2;Q5QPL9;Q9UKM9;Q5QPM0;Q5QPM1 Q9UKM9-2 RALY RNA-binding protein Raly 1 STAVT(0.056)T(0.046)S(0.499)S(0.4)AK 76.655 0.022838999999999998 2557900.0 19694.0 22177.0 19955.0 24206.0 29172.0 29501.0 22646.0 30690.0 27177.0 28957.0 True False 23027.805225769593 24378.585997312923 20430.80287975894 22849.81629691083 23455.95601295419 27953.915626457605 20500.80693715815 29884.420018742883 27574.41221116729 34206.67487651411 0.6731962492378997 0.712685055923134 0.5972753257518895 0.6679929101381099 0.6857128352179815 0.8172064583117498 0.5993218285953236 0.8736429403508368 0.8061120325407469 1.0 15.061990250614826 -8.465581861166799 0.54839095375901 1.006426043232888 0.6619844208666954 0.6723704028009859 0.0699121208096365 0.5290030183610235 0.38680338594129327 0.07356164536989757 0.03434695176276269 3.4230885896011957e-09 8.465581861166799 -0.3444416223661926 STAVTTSS(ph)AK ddPTM_PC-9_Lapatinib_30min_R1 3 STAVTTSSAK 10 0 Q9UKM9-2;Q5QPL9;Q9UKM9;Q5QPM0;Q5QPM1 Q9UKM9-2 RALY RNA-binding protein Raly 1 STAVT(0.006)T(0.005)S(0.043)S(0.946)AK;STAVT(0.011)T(0.008)S(0.082)S(0.899)AK;STAVT(0.051)T(0.035)S(0.359)S(0.555)AK 107.83 0.0021154 6478500.0 77399.0 94096.0 83456.0 87285.0 93124.0 78900.0 86456.0 100057.0 92266.0 74512.0 True False 76295.2760667616 93878.12649324111 76594.56982947615 93704.2300742241 87646.62940882817 75525.63092488323 90932.26864754311 104706.01349603671 81874.0314759468 87391.29991900107 0.8730305664005014 1.0742273725216627 0.8764553210727852 1.0722375128997301 1.00292168087743 0.8642236812461243 1.0405185496934362 1.1981285733600924 0.9368670743178329 1.0 16.415202041558324 -7.5032896739177435 24.813093291455772 1.0643634009099225 0.9674946828475719 0.14540198668219917 0.0947552722406043 1131.4855824329413 1433235.8302242619 0.03813794792562702 0.02527763748703012 3.1384146766364115e-08 7.5032896739177435 -0.09686871806235064 STAYEDYYYHPPPR ddPTM_PC-9_AZD4547_30min_R2 2 STAYEDYYYHPPPR 14 0 O43390-4;O43390;O43390-2;B4DT28;O43390-3;A0A286YEZ8 O43390-4 HNRNPR Heterogeneous nuclear ribonucleoprotein R 0 ; 121.56 5.9148000000000004e-05 9048400.0 30766.0 36734.0 45502.0 68475.0 54247.0 48685.0 42045.0 52255.0 39785.0 54352.0 False True 40548.948027445826 48607.547127477934 44898.61374952135 52689.14667820396 46715.740421379676 45640.71925373027 45786.92354804236 44180.19045044253 41887.95387731273 52449.15302346122 0.7731096822346727 0.92675561616286 0.8560407778069855 1.0045757393762942 0.8906862690515344 0.870189824291625 0.8729773677672401 0.8423432582539537 0.7986392813354998 1.0 15.678631855140965 -9.854567604272619 15.452112209324843 0.9999999999999846 0.875574185339779 0.2840338150491619 0.06117912393945866 0.0 0.0 0.05971321943738455 0.014482582999177773 1.3977593167555656e-10 9.854567604272619 -0.12442581466020552 STAYEDYYYHPPPR ddPTM_PC-9_Lapatinib_30min_R1 2 STAYEDYYYHPPPR 14 0 O43390-4;O43390;O43390-2;B4DT28;O43390-3;A0A286YEZ8 O43390-4 HNRNPR Heterogeneous nuclear ribonucleoprotein R 0 ; 176.99 7.9044e-05 13173300.0 65585.0 62023.0 69121.0 63615.0 59444.0 66731.0 61427.0 54097.0 73537.0 50702.0 False True 64649.74587318403 61879.38955418175 63438.13819477602 68293.45931341898 55947.62079140058 63877.070687558735 64607.38949538064 56610.54411080791 65254.48868106029 59465.773143831684 1.0871757391737549 1.040588329769331 1.0668008644457754 1.1484498679305069 0.9408373562398383 1.0741821271381995 1.086463457544103 0.9519853374121994 1.0973453338145838 1.0 15.85977191144056 -6.247510506465805 24.988838565976717 1.0282535821297816 1.0811738183538389 0.2189936238522412 0.05562738269279764 1440.2990926503567 2583941.4421863738 0.016053410262940108 0.020628855906168544 5.655740745377988e-07 6.247510506465805 0.05292023622405728 STCS(ph)CPDLQPNGQDLGENSR ddPTM_PC-9_AZD4547_30min_R2 2 STCSCPDLQPNGQDLGENSR 20 0 F5H7V1;O43847;O43847-2 F5H7V1 NRD1 Nardilysin 1 S(0.002)T(0.002)CS(0.996)CPDLQPNGQDLGENSR;STCS(1)CPDLQPNGQDLGENSR 244.89 2.5594999999999997e-54 12406800.0 12345.4 12429.900000000001 19474.2 24961.0 24346.6 20233.6 15031.300000000001 23484.4 15678.900000000001 17138.2 True False 16270.980399727943 16447.62209505739 19215.959383783775 19206.627093605704 20966.494842906744 18968.38979341227 16369.056580513474 19855.42559782553 16507.654644891252 16538.196834462095 0.9838424685950449 0.9945233001934065 1.1619138154010715 1.1613495283586883 1.2677618396231092 1.1469442517388695 0.9897727511867456 1.200579833253105 0.9981532333980209 1.0 14.013514325074897 -10.720901061914322 14.523520784640793 0.9999999994356179 1.106981423088198 0.08364057297467775 0.0977614290786758 0.0 0.0 0.09877795443485886 0.023957172918668918 1.9015114202918833e-11 10.720901061914322 0.10698142365258012 STCS(ph)CPDLQPNGQDLGENSR ddPTM_PC-9_Lapatinib_30min_R1 2 STCSCPDLQPNGQDLGENSR 20 0 F5H7V1;O43847;O43847-2 F5H7V1 NRD1 Nardilysin 1 S(0.011)T(0.011)CS(0.977)CPDLQPNGQDLGENSR;S(0.002)TCS(0.998)CPDLQPNGQDLGENSR 188.9 8.562999999999999e-12 12107100.0 23955.0 28903.0 33057.0 28688.0 30943.0 30995.0 26710.0 30440.0 33129.0 29289.0 True False 23613.39730719101 28836.07687929501 30339.181063710137 30797.81122036258 29122.99357627867 29669.416102873955 28092.913106966276 31854.353526683408 29397.663156164177 34351.56462486068 0.6874038363336058 0.8394399845888232 0.8831964830432577 0.896547553414024 0.8477923464132978 0.8636991190032086 0.8178059256909382 0.927304298204513 0.8557881854059335 1.0 15.068088191114514 -1.522878745364596 0.03359723326564868 1.4319269130474708 2.644715194534596e-13 0.5236225421376066 0.052627813847221705 996.022350896938 2.5696834690991683 33.09927417518287 88.98463463433362 0.029999999994179634 1.522878745364596 -1.4319269130472063 STDEYS(ph)EADEEEEEEEGKPSR ddPTM_PC-9_Lapatinib_30min_R1 2 STDEYSEADEEEEEEEGKPSR 21 1 Q96T23-3;Q96T23-2;Q96T23 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 S(0.013)T(0.013)DEYS(0.973)EADEEEEEEEGKPSR;S(0.011)T(0.003)DEYS(0.986)EADEEEEEEEGKPSR 117.51 1.3321000000000001e-06 16578000.0 19907.8 21068.0 17222.0 17413.4 14486.4 13593.8 8369.4 11236.6 12299.900000000001 8420.2 True False 19623.9111213566 21019.218340414074 15806.073638842485 18694.03952539952 13634.338433358209 13012.42486269554 8802.726580211285 11758.693457225068 10914.555738310957 9875.620350788753 1.9871066752570397 2.128394733069634 1.6005145071803084 1.8929483780638094 1.3806057694663456 1.3176311361195912 0.8913593544033133 1.1906789689708877 1.1052020380106273 1.0 13.269655660575529 -6.343677170177616 0.9096961449082779 1.0395817913597392 2.025036815330352 0.8714525132734435 0.1474188980128176 0.19159871532511535 0.34208449887509407 0.07374430891547444 0.10830972961701692 4.5323436336855403e-07 6.343677170177616 0.985455023970613 STDS(ph)PGADAELPESAAR ddPTM_PC-9_AZD4547_30min_R2 1 STDSPGADAELPESAAR 17 0 A0A0J9YWL0;A0A494C1M5;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 S(0.012)T(0.005)DS(0.983)PGADAELPESAAR 227.0 4.5921999999999993e-29 22655000.0 10327.0 12249.0 15749.0 12927.0 12326.0 14398.0 12391.0 16547.0 7003.5 11490.0 True False 13610.77118505601 16208.24970774969 15540.157969786196 9946.879870159088 10614.747662247246 13497.690783921282 13493.774995452326 13990.041362232761 7373.690712071372 11087.738597283807 1.2275515936487065 1.4618174450577566 1.4015624406579272 0.8971062749076535 0.9573410816924894 1.2173529043359523 1.2169997404843158 1.2617578633807203 0.6650310744048137 1.0 13.43667752979524 -5.746552741481568 24.991745917615006 1.0541757674034988 1.373461322141966 0.42082439983259223 0.17735031922061414 247.00739229772006 414673.59319097054 0.04918422213184833 0.08474273873975306 1.7924508607794103e-06 5.746552741481568 0.3192855547384672 STDS(ph)PVPGSEDDLVAGATLHSPEWSEER ddPTM_PC-9_Lapatinib_30min_R1 2 STDSPVPGSEDDLVAGATLHSPEWSEER 28 0 Q9H694-2;Q9H694 Q9H694-2 BICC1 Protein bicaudal C homolog 1 1 S(0.16)T(0.16)DS(0.511)PVPGS(0.169)EDDLVAGATLHSPEWSEER;S(0.048)T(0.048)DS(0.657)PVPGS(0.248)EDDLVAGATLHSPEWSEER 83.56200000000001 9.9213e-07 6053800.0 27584.0 16818.5 22766.0 21257.0 25116.0 22955.0 17635.2 24731.8 20349.7 19141.8 True False 27190.64710171394 16779.557796575555 20894.267359301364 22820.310691273247 23638.726259955863 21973.26816071856 18548.264366303683 25880.929715874805 18057.702494159013 22450.434625154758 1.2111412342658159 0.7474045860018573 0.9306843144983138 1.0164752296467374 1.0529295603689417 0.9787457805426379 0.8261873177956716 1.1528030591833764 0.8043364324860831 1.0 14.454455754381614 -4.723013709980216 24.4855355842785 0.9527038991662037 1.211144486562527 0.3140055716612563 0.11735364437588428 7483.881446726081 4768461.072183872 0.028143265199469983 8.516873540212652 1.8922838813350315e-05 4.723013709980216 0.25844058739632325 STDSEVSQS(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 4 STDSEVSQSPAK 12 0 A0A0G2JNJ7;H7C148;H7C3F5;A0A2H2FJL5;B7Z6J7;O75175 A0A0G2JNJ7 CNOT3 CCR4-NOT transcription complex subunit 3 1 STDS(0.001)EVS(0.016)QS(0.983)PAK;STDSEVS(0.002)QS(0.998)PAK;STDSEVSQS(1)PAK;STDSEVSQS(1)PAK 196.84 1.1635e-05 293865000.0 172912.0 151119.0 178147.0 206943.0 197577.0 185665.0 176967.0 201198.0 179211.0 195015.0 True False 227894.41920697276 199965.26145688866 175784.65438081816 159235.48858747812 170146.8439772696 174055.3381995239 192716.72016949518 170107.4721700916 188683.72759349225 188187.58420794617 1.2109960397554749 1.0625847730524465 0.9340927305096661 0.8461529981251252 0.904134269502383 0.924903409181308 1.0240671348251347 0.9039250537491562 1.0026364299623394 1.0 17.52181192294696 -4.93734889857144 2.398085059314854 0.9366843075114609 1.230880209038039 0.724711921754994 0.051838889691019074 0.20803984193852174 1.9004419417066127 0.014318602367569917 0.11210340181402464 1.155183830839563e-05 4.93734889857144 0.29419590152657815 STDSEVSQS(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 STDSEVSQSPAK 12 0 A0A0G2JNJ7;H7C148;H7C3F5;A0A2H2FJL5;B7Z6J7;O75175 A0A0G2JNJ7 CNOT3 CCR4-NOT transcription complex subunit 3 1 STDS(0.018)EVS(0.091)QS(0.89)PAK;STDSEVS(0.029)QS(0.971)PAK;STDSEVS(0.001)QS(0.999)PAK;STDSEVSQS(1)PAK;STDSEVS(0.015)QS(0.985)PAK;STDS(0.001)EVS(0.009)QS(0.99)PAK 146.84 8.298e-05 317827700.0 227386.0 257309.0 251070.0 276673.0 306508.0 290263.0 289403.0 288941.0 268874.0 224519.0 True False 265877.9587217856 282852.9370240607 257056.46098827763 261171.9087959691 246449.95768608822 275041.09730119206 261988.6527437241 281356.6049082956 272805.7735903664 265222.51740857365 1.002471288334098 1.066474067842164 0.9692105462986905 0.9847275086135895 0.929219585478987 1.0370201594817567 0.9878069754542455 1.0608322689090064 1.0285920526503065 1.0 18.0168437399877 -7.742443199246239 24.993115872642285 1.0335341334080503 0.996824698233409 0.13936726996615667 0.03735425157102097 433.5841970237199 570465.1712237564 0.01813104208157233 0.010447478104823662 1.8094925557199866e-08 7.742443199246239 -0.036709435174641314 STDSEVSQS(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 4 STDSEVSQSPAK 12 0 A0A0G2JNJ7;H7C148;H7C3F5;A0A2H2FJL5;B7Z6J7;O75175 A0A0G2JNJ7 CNOT3 CCR4-NOT transcription complex subunit 3 1 STDSEVSQS(1)PAK;STDSEVSQS(1)PAK;STDSEVS(0.001)QS(0.999)PAK;STDSEVS(0.017)QS(0.983)PAK 186.29 0.000384 313156000.0 529426.0 468752.0 435660.0 516340.0 487953.0 425489.0 364171.0 396061.0 466567.0 332629.0 True False 521876.2881551635 467666.63354403595 399841.71649623243 554313.3660597455 459252.56389250833 407291.8273333035 383025.9924776117 414463.43995176686 414017.31129168003 390123.4794497173 1.3377207875088373 1.1987656682537948 1.024910669463481 1.420866457055145 1.1771979593238018 1.044007471449303 0.9818070755902288 1.0623904014605372 1.0612468438855969 1.0 18.57357130352554 -6.699544939953219 4.074673161528017 1.029520467346924 1.233675010505073 0.5201504746839978 0.09828144469052012 0.19212782478053622 6.383757620651777 0.03432165248555004 0.03340859082070779 1.997354075411232e-07 6.699544939953219 0.20415454315814907 STEDLS(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 2 STEDLSPQK 9 0 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 S(0.001)T(0.001)EDLS(0.998)PQK;STEDLS(1)PQK 115.29 0.0019879999999999997 35166000.0 228700.0 343320.0 277080.0 284330.0 302440.0 232380.0 317470.0 330160.0 253600.0 235140.0 True False 301421.8427444861 454291.4760114807 273405.7381591445 218782.11135470963 260451.42649440718 217849.24186467731 345724.21497911756 279141.35832203855 267004.7782653387 226907.82017104555 1.3283889577594599 2.002097043940711 1.2049198566759325 0.9641893839965028 1.1478292211263414 0.9600781572907457 1.5236328775205146 1.2301971704263819 1.1767103401904246 1.0 17.791746805472492 -5.386630069030632 7.6786944226012235 1.155767893371952 1.6626993938953618 0.47591632480765966 0.2163348740228553 0.20937294035711732 12.032717437935284 0.05521487360146422 0.11551994692356492 4.1055366268649405e-06 5.386630069030632 0.5069315005234099 STEDLS(ph)PQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STEDLSPQK 9 0 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 STEDLS(1)PQK;ST(0.001)EDLS(0.999)PQK 102.53 0.0031473000000000004 30856000.0 272860.0 234370.0 208360.0 188282.0 383260.0 215340.0 212290.0 201129.0 205510.0 203812.0 True False 319049.8087693456 257636.7047026304 213328.09260970075 177733.16995848043 308162.9542549296 204047.19131559544 192180.35435349765 195849.57686379057 208515.1949632772 240761.50222509546 1.325169538405089 1.0700909502622964 0.8860556635431425 0.7382125809811243 1.2799511192899038 0.8475075517880152 0.7982187873783169 0.8134588588863542 0.8660653511304719 1.0 17.877245197974744 -4.878675544981518 2.3768085770684504 0.8992973891148426 1.377981294666962 0.4546919793576595 0.1426488289153825 0.41637974881757944 3.430550427026391 0.03862924121032985 0.3838925889997614 1.322283123540624e-05 4.878675544981518 0.4786839055521195 STEDLS(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 2 STEDLSPQK 9 0 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 STEDLS(1)PQK;STEDLS(1)PQK 118.77 0.0017779 37923000.0 592350.0 654750.0 290630.0 208546.0 311360.0 204049.0 193048.0 183666.0 348880.0 154041.0 True False 583902.9803763131 653233.9666027204 266735.52326424344 223883.16852906157 293046.4169573122 195322.2999314512 203043.08084888174 192199.79286569732 309585.4605307304 180666.78160326937 3.2319332596432697 3.6156838617802634 1.4763949459728272 1.2392049415076876 1.6220271062381575 1.0811190535311812 1.123853976071534 1.0638358150849976 1.7135715696234448 1.0 17.462971743108902 -5.294118545354151 5.711305189913106 1.280303915328108 3.4315746244319216 0.9243979060525728 0.244266293439408 0.03837974134648174 3.8305594425282425 0.0626236658558045 0.1393991396825138 5.080207538993611e-06 5.294118545354151 2.1512707091038137 STEGGQSLDSLIKVT(ph)PER ddPTM_PC-9_AZD4547_30min_R2 2 STEGGQSLDSLIKVTPER 18 1 O95171-2;O95171;O95171-3 O95171-2 SCEL Sciellin 1 STEGGQSLDS(0.003)LIKVT(0.997)PER;S(0.002)T(0.002)EGGQSLDS(0.051)LIKVT(0.945)PER 77.681 0.0034762 19097300.0 59301.0 52609.0 58051.0 79775.0 76593.0 59770.0 57229.0 73788.0 58819.0 60604.0 True False 78157.48446257449 69613.83042493301 57281.2058101504 61384.10626146368 65959.3840414167 56032.57245138045 62322.270132736754 62385.76007955714 61928.052258631535 58482.272406421944 1.3364303616559197 1.1903407231024201 0.9794627235425336 1.0496190338650913 1.127852618021281 0.958112093558586 1.0656608843724262 1.066746511592572 1.058920074587102 1.0 15.835711749762199 -4.9808385534546975 3.159628980279588 1.0428079290298249 1.333642469091657 0.7995616554970064 0.04763881048384522 0.1093761976252006 2.1055603261494102 0.012223011407168038 0.06252686009639391 1.045108660316702e-05 4.9808385534546975 0.2908345400618322 STEGGQSLDSLIKVT(ph)PER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 STEGGQSLDSLIKVTPER 18 1 O95171-2;O95171;O95171-3 O95171-2 SCEL Sciellin 1 STEGGQSLDS(0.012)LIKVT(0.988)PER;STEGGQSLDSLIKVT(1)PER;STEGGQSLDS(0.002)LIKVT(0.998)PER 83.064 0.0017221 23881600.0 79697.0 82260.0 82234.0 91796.0 93548.0 92370.0 94342.0 80397.0 68943.0 63961.0 True False 93188.12801249929 90426.22916259927 84194.77043418167 86652.96772664726 75217.94093993705 87525.95459190846 85405.24278306881 78286.66393766268 69951.16094765814 75556.62298500257 1.2333548579983047 1.1968008308225766 1.114326806941778 1.1468613114676556 0.9955175068487014 1.1584153861572362 1.1303475381638102 1.0361323844926473 0.9258111093919976 1.0 16.205270601237807 -1.522878745287845 0.17774954436751814 0.9642223548689147 2.1069924258393162 0.6036546367179867 0.05933784090442657 42.813065616921136 0.47822364582198795 0.14630681038504548 13.166061167460198 0.029999999999481407 1.522878745287845 1.1427700709704016 STEGGQSLDSLIKVT(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 2 STEGGQSLDSLIKVTPER 18 1 O95171-2;O95171;O95171-3 O95171-2 SCEL Sciellin 1 STEGGQSLDS(0.004)LIKVT(0.996)PER;STEGGQSLDS(0.001)LIKVT(0.999)PER 64.34899999999999 0.011552 17074100.0 92900.0 76270.0 88348.0 78841.0 74757.0 75194.0 64770.0 59764.0 75891.0 57371.0 True False 91575.22896422633 76093.40150101473 81084.36847314225 84639.2301458662 70359.9402379169 71978.12790577525 68123.47367795596 62540.853619208516 67343.35641234138 67287.50090794782 1.3609545268965357 1.1308697822663047 1.2050435426940458 1.2578744789713068 1.0456613678396574 1.0697102275241936 1.012423893869261 0.9294572212566949 1.0008301022276036 1.0 16.038050919261245 -6.512845882850084 1.0497028783203672 0.9758204119563112 1.243888894145955 0.7561408122921476 0.06351918412902263 0.251363073367109 0.5922612282849359 0.030823380607511722 0.03605770463259733 3.0701112788974893e-07 6.512845882850084 0.26806848218964374 STELKTEIKEEEDQPSTS(ph)ATQSSPAPGQSK ddPTM_PC-9_AZD4547_30min_R2 1 STELKTEIKEEEDQPSTSATQSSPAPGQSK 30 2 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 1 STELKTEIKEEEDQPS(0.126)T(0.061)S(0.202)AT(0.202)QS(0.202)S(0.202)PAPGQS(0.003)K 42.536 0.014666 8033700.0 35488.0 23271.0 28580.0 61621.0 46783.0 37642.0 26918.0 29533.0 26466.0 45444.0 True False 46772.4458037443 30792.895660792154 28201.01052615972 47415.23048495959 40287.9879833614 35288.239789440544 29313.649852924347 24969.353450826136 27864.93872859014 43853.019392077076 1.0665729852160344 0.7021841617217242 0.6430802466307439 1.0812306915752783 0.9187049955023219 0.804693502947623 0.6684522584600057 0.5693873260489185 0.6354166512334724 1.0 15.42038855886734 -7.1027530239165095 3.810458206039608 0.6833691967963439 0.8696837584276047 0.16023499049179946 0.16778296097488493 0.4004873157788718 10.446698144303577 0.06756826568900527 0.05199468144624097 7.893088568935721e-08 7.1027530239165095 0.1863145616312608 STELKTEIKEEEDQPSTSATQS(ph)SPAPGQSK ddPTM_PC-9_AZD4547_30min_R2 3 STELKTEIKEEEDQPSTSATQSSPAPGQSK 30 2 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 1 STELKTEIKEEEDQPS(0.006)T(0.025)S(0.021)AT(0.092)QS(0.428)S(0.428)PAPGQSK;S(0.001)T(0.001)ELKTEIKEEEDQPS(0.032)T(0.032)S(0.032)AT(0.079)QS(0.41)S(0.41)PAPGQS(0.004)K;STELKTEIKEEEDQPS(0.008)T(0.033)S(0.028)AT(0.028)QS(0.449)S(0.449)PAPGQS(0.004)K 57.803000000000004 0.00049262 26024400.0 103691.0 63453.0 98128.0 171876.0 143567.0 101004.0 78857.0 86554.0 85193.0 117249.0 True False 136662.5810932162 83962.94135895516 96826.75860430386 132252.64365772903 123635.20019680749 94688.20391298713 85875.12023374882 73179.0681130535 89696.12805504345 113144.14819781789 1.207862565320474 0.7420882360805512 0.8557822931771497 1.1688862903143908 1.0927228863895582 0.8368811416339187 0.7589886140961288 0.6467773126464249 0.79275976251305 1.0 16.78780244495144 -6.927325198158342 5.582297725937223 0.7736275555310601 0.9974898469377212 0.30445913251850276 0.1536779174424331 0.2557088442697014 14.218021033102568 0.05650638748791171 0.04955871582095994 1.1821560300103474e-07 6.927325198158342 0.22386229140666114 STELKTEIKEEEDQPSTSATQS(ph)SPAPGQSK ddPTM_PC-9_Lapatinib_30min_R1 3 STELKTEIKEEEDQPSTSATQSSPAPGQSK 30 2 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 1 STELKTEIKEEEDQPS(0.001)T(0.006)S(0.015)AT(0.02)QS(0.479)S(0.479)PAPGQS(0.001)K;STELKTEIKEEEDQPS(0.001)T(0.001)S(0.004)AT(0.023)QS(0.483)S(0.483)PAPGQS(0.006)K;STELKTEIKEEEDQPS(0.008)T(0.021)S(0.021)AT(0.036)QS(0.453)S(0.453)PAPGQS(0.009)K 58.357 0.00045448 29961000.0 243565.0 101225.0 126430.0 121669.0 104916.0 116667.0 79889.0 77534.0 122425.0 92427.0 True False 240091.7184356496 100990.61973174522 116035.41343391324 130616.9441358857 98745.04715279235 111677.42437406014 84025.26152012087 81136.51269178295 108636.20730759746 108402.88379876371 2.214809329993007 0.9316229992480788 1.070408916881938 1.2049213042926017 0.9109079361403345 1.0302071352767257 0.7751201681691714 0.7484719026700679 1.0021523736330382 1.0 16.726043611080954 -4.760616722398418 24.999857762895125 0.9612960363663129 2.2148107874045166 0.8965384165154618 0.12749508271357163 6.431502247732104 195330.93075278235 0.03486612816511322 0.20410439778074105 1.7353348059607206e-05 4.760616722398418 1.2535147510382036 STELVLS(ph)PDMPR ddPTM_PC-9_AZD4547_30min_R2 1 STELVLSPDMPR 12 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 S(0.001)T(0.001)ELVLS(0.997)PDMPR 72.29 0.022349 3400500.0 20481.0 19821.0 19206.0 28104.0 22782.0 27131.0 19262.0 28707.0 18625.0 17471.0 True False 26993.53196873554 26227.750629219274 18951.31589102253 21625.057002471647 19619.112545944885 25434.49428105073 20976.28068456158 24270.992771234425 19609.4794763089 16859.34560775854 1.6011019998494678 1.5556802286056386 1.124083717834296 1.282674755330952 1.1636935977465415 1.5086287969175964 1.244193053074875 1.4396165388569473 1.163122219126036 1.0 14.041260918987 -1.5228787452880044 0.03143248651271147 4.810006948708794e-10 3.2530464132026027 0.3876985533890015 0.15254558942462257 1576.5540756191265 3.8107086952368463 123.15383240677765 310.8020936976589 0.029999999999470395 1.5228787452880044 3.253046412721602 STETSDFENIES(ph)PLNER ddPTM_PC-9_AZD4547_30min_R2 2 STETSDFENIESPLNER 17 0 Q96K76-2;Q96K76-4;Q96K76 Q96K76-2 USP47 Ubiquitin carboxyl-terminal hydrolase 47 1 STETSDFENIES(1)PLNER;STETSDFENIES(1)PLNER 134.82 3.4262e-05 16050500.0 10550.0 10335.8 14881.2 16297.7 15130.9 14092.400000000001 11397.7 16089.4 10861.900000000001 11846.3 True False 13904.68054636785 13676.645222414836 14683.865564796644 12540.51706195495 13030.235713345506 13211.200000231456 12412.073219729396 13603.152927630856 11436.03785899165 11431.564642733085 1.2163409805154621 1.1963931141402349 1.2845018178794108 1.0970079296998783 1.1398470918527044 1.1556773209194653 1.0857720362557377 1.1899642221135691 1.000391303937682 1.0 13.48073525885213 -6.837301643060016 0.1728681738981412 0.9443268408240761 1.3404208889154285 0.594507949405072 0.055657273562111344 5.071156380878526 0.4308571525040506 0.2801083795895863 0.5988773286521895 1.4544485296341666e-07 6.837301643060016 0.3960940480913524 STETSDFENIES(ph)PLNER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STETSDFENIESPLNER 17 0 Q96K76-2;Q96K76-4;Q96K76 Q96K76-2 USP47 Ubiquitin carboxyl-terminal hydrolase 47 1 STETSDFENIES(1)PLNER;STETSDFENIES(1)PLNER;STETSDFENIES(1)PLNER;ST(0.01)ET(0.009)S(0.212)DFENIES(0.769)PLNER 225.17 7.079299999999999e-81 13463300.0 50153.0 58358.0 62331.0 59270.0 75456.0 63274.0 64693.0 58091.0 55590.0 50075.4 True False 58642.91233309749 64151.39656541408 63817.20743163389 55949.29405593264 60670.93846542822 59955.800052488994 58564.810703239964 56566.17280250223 56402.89858405232 59153.673623351715 0.9913655186741843 1.0844871101985025 1.0788376025126727 0.9458295762352432 1.0256495454827939 1.0135600442035881 0.9900452011846093 0.9562579859819893 0.9534978155910592 1.0 15.852180146654119 -6.381531122107105 0.6925104284687567 0.9707558829174926 1.049744116689877 0.28509426494304535 0.03895168632431701 0.968497620808753 1.0191771483660756 0.026326557825455812 0.04157933285146406 4.154022819077239e-07 6.381531122107105 0.07898823377238451 STETSDFENIES(ph)PLNER ddPTM_PC-9_Lapatinib_30min_R1 2 STETSDFENIESPLNER 17 0 Q96K76-2;Q96K76-4;Q96K76 Q96K76-2 USP47 Ubiquitin carboxyl-terminal hydrolase 47 1 STETSDFENIES(1)PLNER;STETSDFENIES(1)PLNER 102.89 0.00091852 16126700.0 15794.5 12226.4 16195.099999999999 15991.2 15559.3 15738.9 16834.8 14826.5 13687.1 11576.8 True False 15569.267533643437 12198.090521987782 14863.60139289386 17167.24619307941 14644.132564760772 15065.78393616787 17706.423570690968 15515.393316799325 12145.514666447367 13577.834454883632 1.146667945126075 0.8983826222450674 1.0946960240443766 1.2643581898219969 1.0785322662034384 1.1095866565635626 1.3040683055553368 1.1427001388442175 0.894510439555323 1.0 13.728965780315463 -4.3902822725327555 22.656049715226438 1.09998518639654 48.27104721994813 0.010496931462499526 0.12803666082923126 6783.013246014821 1161773.6270753923 0.031719252268812115 40176.843693645395 4.071155843628888e-05 4.3902822725327555 47.17106203355159 STFAGS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 1 STFAGSPER 9 0 H0YE03;H7C3G7;Q2TBE0-3;Q2TBE0-2;Q2TBE0 H0YE03 CWF19L2 CWF19-like protein 2 1 S(0.004)T(0.012)FAGS(0.984)PER 68.355 0.04328 17732000.0 30941.0 35790.0 31687.0 27031.0 33924.0 32404.0 37891.0 33827.0 34748.0 34146.0 True False 30499.775666115536 35707.13045393106 29081.81717535721 29018.94991277261 31928.657017150144 31018.1564574134 39852.810577913086 35398.72591153481 30834.31432733836 40048.09060331498 0.7615787720873494 0.8916063142090325 0.7261723776900855 0.7246025834342915 0.7972579100814172 0.7745227298014021 0.995123861775679 0.8839054591183102 0.769932195588522 1.0 15.289445839591782 -7.229862369766493 24.389333663816938 0.902565841032436 0.7803118502040904 0.43281573679984986 0.0742246422002003 521.6857108519814 402938.0214194255 0.028571722415460608 0.022129180090328517 5.890302926165948e-08 7.229862369766493 -0.12225399082834554 STFETEHAGQR ddPTM_PC-9_AZD4547_30min_R2 1 STFETEHAGQR 11 0 H0YIQ2;P49750-3;P49750-1;P49750;F8VU51;H0YI23 H0YIQ2 YLPM1 YLP motif-containing protein 1 0 113.69 0.0010375999999999999 0.0 9672.4 9623.1 14155.0 19970.0 14336.0 14122.0 9901.8 16473.0 13002.0 16703.0 False True 12748.022001581843 12733.578885022947 13967.295451287298 15366.22503342438 12345.693857372742 13238.949107552195 10783.041017671678 13927.476361881938 13689.259175890915 16118.233053997517 0.7909069163397026 0.7900108431466603 0.8665525187838898 0.9533442643462318 0.7659458587063214 0.8213647899990362 0.6689964701185005 0.8640820811576337 0.8493027200953527 1.0 13.976405978008689 -8.781604072562974 1.8471507308739075 0.9995633355301855 0.8145160841069692 0.38572960663187117 0.06997567426858713 1.1406600252746208 6.280724172398732 0.0703428955262794 0.019698030079080726 1.6534685068251866e-09 8.781604072562974 -0.18504725142321632 STFETEHAGQR ddPTM_PC-9_Lapatinib_30min_R1 1 STFETEHAGQR 11 0 H0YIQ2;P49750-3;P49750-1;P49750;F8VU51;H0YI23 H0YIQ2 YLPM1 YLP motif-containing protein 1 0 129.82 0.0002017 1918500.0 10869.0 9238.0 17422.0 10548.0 12612.0 14470.0 10479.0 9342.8 13764.0 10899.0 False True 10714.006066869517 9216.60997858103 15989.630410864815 11323.735107096501 11870.18695614603 13851.15183121749 11021.551345859207 9776.900595568259 12213.75337865447 12782.87762799537 0.8381529088102287 0.7210121419292966 1.2508631370957066 0.885851796179035 0.9286005312410652 1.0835707134426857 0.8622120673142689 0.7648434789171557 0.9554776110744829 1.0 13.641925025874635 -10.188396036860627 13.269237373031872 1.0000003395460695 0.9226090301214998 0.02556470094661112 0.14575275716384958 0.0 0.0 0.14234770972355623 0.03452439075029322 6.480432078613354e-11 10.188396036860627 -0.07739130942456973 STFREES(ph)PLR ddPTM_PC-9_AZD4547_30min_R2 1 STFREESPLR 10 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 S(0.001)TFREES(0.999)PLR 108.9 0.0094637 166510000.0 69131.0 56434.0 101820.0 153030.0 116700.0 82707.0 71543.0 95906.0 86347.0 82840.0 True False 91113.21998587277 74675.18687298117 100469.8002719939 117751.29778993141 100498.21938863018 77535.31821543115 77910.18840284436 81085.9314006343 90911.12613910563 79939.79681453378 1.1397729743704772 0.9341428155769911 1.2568183092220166 1.4729997133107944 1.25717381571276 0.9699213821536075 0.9746107884612434 1.0143374718447138 1.1372448988083639 1.0 16.286626285369643 -6.760742155836891 24.999950563261578 1.0173307296771343 1.2137046650524037 0.34927531031326675 0.13166791487901416 24.881215236665177 892168.9879091132 0.05070092207621632 0.047870934390600334 1.734833676911193e-07 6.760742155836891 0.19637393537526937 STFREES(ph)PLR ddPTM_PC-9_Lapatinib_30min_R1 2 STFREESPLR 10 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 STFREES(1)PLR;S(0.001)T(0.001)FREES(0.997)PLR 113.38 0.0063495 483130000.0 233997.0 204710.0 268470.0 233506.0 218296.0 238020.0 180238.0 185560.0 250348.0 187063.0 True False 230660.1598702058 204236.0065723449 246397.4329241695 250678.81019318165 205456.25846644863 227840.4394517199 189569.8417286927 194181.7950200843 222151.17195868853 219396.59030421995 1.0513388542199655 0.9308987267721296 1.1230686519900315 1.1425829811009602 0.9364605811856904 1.0384866926864795 0.8640509930707271 0.8850720731385466 1.0125552619147318 1.0 17.743181579077564 -6.65189307854215 1.9671923192210365 0.9395686897550587 1.052705218104411 0.26388271333619906 0.07684925104150839 0.43788491237544735 3.474427654591897 0.030690341061698292 0.03039595536938174 2.2289838480851606e-07 6.65189307854215 0.11313652834935228 STFS(ph)PISDIGLAK ddPTM_PC-9_AZD4547_30min_R2 1 STFSPISDIGLAK 13 0 Q8TEK3-1;Q8TEK3;H7C2S2 Q8TEK3-1 DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 1 S(0.001)T(0.048)FS(0.95)PISDIGLAK 172.58 0.00020585 4665100.0 34342.0 28657.0 42731.0 52477.0 47374.0 46185.0 32796.0 43480.0 42815.0 40877.0 True False 45262.041642025135 37919.81483182165 42164.35902006057 40379.238411567894 40796.937834763994 43297.04464893767 35714.78046572952 36761.165071002644 45078.11349144515 39445.90867199046 1.1474457850216686 0.9613117331670837 1.0689159012833291 1.0236610023954187 1.0342501721536679 1.0976308090395648 0.905411528549466 0.9319386042463211 1.1427829909126666 1.0 15.267588051278045 -7.237590657592472 24.973940997651408 0.989361464134071 1.0494447676396828 0.133032082840554 0.07413815241665622 1610.0874797774898 1686056.223763168 0.02764994858155788 0.02140551201247892 5.786411862329089e-08 7.237590657592472 0.06008330350561175 STFS(ph)PISDIGLAK ddPTM_PC-9_Lapatinib_30min_R1 2 STFSPISDIGLAK 13 0 Q8TEK3-1;Q8TEK3;H7C2S2 Q8TEK3-1 DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 1 S(0.023)T(0.017)FS(0.959)PIS(0.001)DIGLAK;S(0.008)T(0.018)FS(0.72)PIS(0.254)DIGLAK 127.79 0.00089294 4379500.0 32667.0 26027.0 27554.0 29075.0 35442.0 34530.0 31079.0 24108.0 36106.0 25288.0 True False 32201.162589605905 25966.736080594113 25288.616481515834 31213.272491356725 33357.37124165299 33053.23239336146 32688.1185492851 25228.14569058093 32039.362066964393 29658.997105858038 1.0857131303082987 0.875509579366908 0.8526457044807156 1.0524048530687404 1.1246965338239463 1.114442011487739 1.1021316207225622 0.8506068361157783 1.080257769762424 1.0 14.856182194642491 -5.788277681759371 24.743911871730386 1.0485623805635733 0.9317114840850164 0.2166333212233581 0.09417899556531564 280.46337553328584 258575.68206538144 0.027677898443725233 0.041065999248914874 1.6282546167313558e-06 5.788277681759371 -0.11685089647855695 STFS(ph)TNYR ddPTM_PC-9_AZD4547_30min_R2 6 STFSTNYR 8 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 ST(0.005)FS(0.498)T(0.498)NYR;S(0.008)T(0.001)FS(0.953)T(0.038)NYR;S(0.017)T(0.123)FS(0.494)T(0.366)NYR;ST(0.001)FS(0.783)T(0.217)NYR;S(0.06)T(0.008)FS(0.701)T(0.231)NYR;S(0.167)T(0.01)FS(0.411)T(0.411)NYR 108.43 0.0037941000000000003 1615913400.0 205826.1 223015.7 272219.0 386564.0 318474.7 266679.0 207526.4 306590.2 252362.0 272686.0 True False 271274.51835116313 295101.16371529084 268609.1981952652 297447.64215426415 274259.98517847573 250003.5199725902 225995.84756809313 259213.72933191614 265701.34011276567 263139.3461391592 1.0309158334979736 1.1214634681019116 1.0207869029712238 1.1303807146992044 1.0422614071307885 0.9500803419963572 0.8588447561489986 0.9850816046142827 1.009736263357026 1.0 18.005467459298472 -6.665436060356417 4.196531724992552 0.9533971390227387 1.0761890322373744 0.5386323873560763 0.050567609796144185 0.16436683362512908 5.287534430082072 0.017371269827403238 0.01715158054464794 2.160548101230833e-07 6.665436060356417 0.12279189321463568 STFS(ph)TNYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 STFSTNYR 8 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.134)T(0.008)FS(0.612)T(0.246)NYR;S(0.038)T(0.001)FS(0.658)T(0.303)NYR;S(0.035)T(0.121)FS(0.422)T(0.422)NYR;S(0.005)T(0.017)FS(0.74)T(0.238)NYR;S(0.001)T(0.007)FS(0.496)T(0.496)NYR;S(0.001)T(0.003)FS(0.964)T(0.033)NYR;S(0.337)T(0.005)FS(0.572)T(0.086)NYR 106.18 0.0038301999999999998 966177300.0 227842.7 225399.0 253005.0 237718.0 289630.0 271714.0 253402.0 239508.0 237599.0 198631.0 True False 266411.96901154995 247775.12310990418 259037.59872680597 224399.431152154 232879.08062635144 257464.83951484048 229397.9280883929 233221.16877970297 241073.43588185325 234641.2279378687 1.1354013587164398 1.0559743711173948 1.1039730784029023 0.9563512479212448 0.9924900354170331 1.0972702528773643 0.9776539702951768 0.9939479554780468 1.0274129486983752 1.0 17.84009700065812 -5.742848920889859 24.998102036753647 1.0081975579627913 1.0942021208462005 0.5300137303797487 0.039617322653883846 207.41418816011384 278902.2050188532 0.010850473476607477 0.01875027939759806 1.8078029015650226e-06 5.742848920889859 0.08600456288340919 STFS(ph)TNYR ddPTM_PC-9_Lapatinib_30min_R1 6 STFSTNYR 8 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.06)T(0.006)FS(0.895)T(0.038)NYR;S(0.025)T(0.003)FS(0.928)T(0.044)NYR;ST(0.001)FS(0.499)T(0.499)NYR;ST(0.001)FS(0.731)T(0.267)NYR;S(0.005)T(0.022)FS(0.487)T(0.487)NYR;S(0.1)T(0.004)FS(0.764)T(0.132)NYR 112.3 0.0037321999999999998 1262453600.0 238695.0 192347.0 253041.0 206586.0 222848.0 224249.0 222511.0 191885.0 223425.0 156199.0 True False 235291.16552869772 191901.63233926406 232236.94574650677 221779.02359069322 209740.5187760253 214658.39301995112 234031.53082531542 200800.6776106324 198260.52373044708 183197.789027915 1.2843559236014848 1.047510635131207 1.2676842170356073 1.2105988001683763 1.1448856445754694 1.1717302602775532 1.277480105339342 1.0960867960040455 1.0822211598865796 1.0 17.483042566421283 -8.201048831920895 1.9753062529850898 1.0166071724946766 1.193690269918657 0.4565370340680255 0.0707657704123405 0.29622281612500057 2.077342972511766 0.06194638615541907 0.018536089959255753 6.294354053795355e-09 8.201048831920895 0.17708309742398032 STFST(ph)NYR ddPTM_PC-9_AZD4547_30min_R2 1 STFSTNYR 8 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.014)T(0.002)FS(0.276)T(0.708)NYR 103.88 0.0094553 40176000.0 24492.0 37651.0 43152.0 43771.0 55060.0 44907.0 29138.0 41800.0 38962.0 46602.0 True False 32279.946534752744 49820.9494445656 42579.77628498409 33680.27220520873 47415.86940478122 42098.958190967736 31731.22555221449 35340.770468443174 41021.451777500544 44970.478164544846 0.7178030532973644 1.1078590105774084 0.9468384153974683 0.7489418298372147 1.0543777015509774 0.9361465545669683 0.7056012488039697 0.7858660150139603 0.9121862486630673 1.0 15.456690603604189 STFSTNY(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 STFSTNYR 8 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 STFST(0.001)NY(0.999)R 107.01 0.005534300000000001 5808500.0 11365.0 18842.0 24978.0 41012.0 30452.0 24831.0 24074.0 32121.0 23239.0 21806.0 True False 14978.833593314761 24932.308024607722 24646.77539966472 31557.31702908364 26224.265439782022 23278.313644641592 26216.5393624824 27157.437517149858 24467.366096641214 21042.578577229844 0.7118345091757596 1.184850418075043 1.171281138820837 1.4996886865962227 1.2462477135838892 1.1062481510622009 1.2458805495848924 1.2905945636594602 1.1627551256060096 1.0 14.361023884210104 -4.745387841189902 3.670224998387258 1.2318454242125696 0.6315426445045244 0.5926110814345957 0.12398124685619659 0.21697284699382188 4.744936331885417 0.031035871853731068 0.3761983265562548 1.797265173327982e-05 4.745387841189902 -0.6003027797080452 STFSTNY(ph)R ddPTM_PC-9_Lapatinib_30min_R1 2 STFSTNYR 8 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 STFST(0.012)NY(0.987)R;STFST(0.012)NY(0.987)R 95.815 0.0091504 8708800.0 24643.0 21182.0 30656.0 20672.9 37636.0 35184.0 38282.0 26842.0 38080.0 26133.0 True False 24291.586301027266 21132.954380418203 28135.582015582113 22193.254028772786 35422.324475222944 33679.262337909924 40264.054644735406 28089.17731153864 33791.02939982288 30650.05422996633 0.7925462747559371 0.6894915820330482 0.9179618999849652 0.724085310331184 1.1557018532316592 1.0988320635655502 1.3136699316299918 0.9164478829559806 1.1024786170455008 1.0 14.90360200606695 -6.262415460825129 24.99991485427063 1.104517052938646 0.7842648983692029 0.6612872568229482 0.11101448836431127 53.538537725753145 1371254.9018396528 0.033390701203643056 0.04008651650831135 5.464929190991701e-07 6.262415460825129 -0.3202521545694432 STFSTNYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 STFSTNYR 8 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ;; 116.25 0.01658 52154200.0 83617.0 73768.0 78993.0 94906.0 95492.0 69038.0 93025.0 82987.0 63830.0 70352.0 False True 97771.70658897024 81091.1995242719 80876.4927026209 89588.72450940328 76781.02809505777 65417.52574554692 84212.99855732285 80808.6791819946 64763.39299550384 83106.26069387452 1.1764661984867364 0.9757531965368388 0.9731696749121338 1.0780021115305285 0.9238898183361178 0.78715520586969 1.0133171418640172 0.9723536892082877 0.7792841652936664 1.0 16.342669544051446 -1.5228787454749733 0.5531696058687586 0.9189657397122708 11.425569898458054 0.3932907054966588 0.08846992738219378 150.69778717255448 1.3663554812692238 0.0442893015846044 1883.5210240180434 0.029999999986555042 1.5228787454749733 10.506604158745784 STFSTNYR ddPTM_PC-9_Lapatinib_30min_R1 4 STFSTNYR 8 0 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ;;; 146.58 0.0056415 261914000.0 262945.0 224026.0 246774.0 256753.0 248942.0 200815.0 227567.0 211713.0 230136.0 212445.0 False True 259195.35608179323 223507.2815611165 226485.1942951873 275635.4721229002 234299.72099880304 192226.61057262906 239349.30576611715 221549.9588763048 204215.66024048437 249165.83518483117 1.0402523921047289 0.8970221836204745 0.9089737127370637 1.1062330111125944 0.9403364663738892 0.771480610213015 0.9606024260451593 0.889166681748158 0.8195973580767895 1.0 17.92674673867166 -6.528644034853751 24.995389823727084 0.8824515178859735 0.9818755855337981 0.24492476756577852 0.08223314112314667 220.8618570332867 957535.9962603373 0.026686420912620353 0.026761365469219322 2.960437965888509e-07 6.528644034853751 0.09942406764782452 STGGAPT(ph)FNVTVTK ddPTM_PC-9_Lapatinib_30min_R1 1 STGGAPTFNVTVTK 14 0 P07737;K7EJ44 P07737 PFN1 Profilin-1 1 STGGAPT(1)FNVTVTK 139.67 0.00026006 5638300.0 30396.0 35666.0 30447.0 31098.0 42581.0 39075.0 32888.0 38327.0 32176.0 28918.0 True False 29962.547466056283 35583.417568312514 27943.765188818794 33385.050659886874 40076.46929746698 37403.85333827391 34590.779717780126 40107.81233959251 28552.00005169907 33916.43776918708 0.8834225949659463 1.0491496132485905 0.8239003570771682 0.9843324610645587 1.1816237769485407 1.1028237574010538 1.019882452077726 1.182547902363445 0.8418336927364 1.0 15.049697031685124 -6.006317548861783 24.80342427104953 1.066242963883142 0.927233335100608 0.2451083784214454 0.10608267420522759 346.43671337135675 1360163.68732753 0.02888036198907469 0.04123023613502804 9.855585981489614e-07 6.006317548861783 -0.1390096287825341 STGGAPTFNVT(ph)VTK ddPTM_PC-9_AZD4547_30min_R2 1 STGGAPTFNVTVTK 14 0 P07737;K7EJ44 P07737 PFN1 Profilin-1 1 STGGAPTFNVT(1)VTK 180.7 0.00010291 6996000.0 19106.0 28996.0 30223.0 45322.0 35715.0 38798.0 22075.0 30910.0 30916.0 29152.0 True False 25181.31057051225 38368.38995231533 29822.223272642615 34873.71311791984 30756.58873577479 36371.954926696635 24039.632235058514 26133.569741138268 32550.156643735063 28131.397353178225 0.8951318789596963 1.3638991860452518 1.060104583438809 1.2396722665459732 1.0933189115932762 1.2929309721113946 0.8545481027213377 0.9289822831422824 1.1570757127732092 1.0 14.779893596063816 -7.262376967359374 24.998906415419658 0.9792333854612398 1.1632803774796283 0.26142650607497353 0.14158641818918752 109.3987789821233 2916834.8532114965 0.05348217097092898 0.0383690848552236 5.46541359361818e-08 7.262376967359374 0.18404699201838848 STGGAPTFNVTVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STGGAPTFNVTVTK 14 0 P07737;K7EJ44 P07737 PFN1 Profilin-1 0 90.434 0.022729 12974000.0 25682.0 24783.0 23925.0 29255.0 24617.0 29948.0 27745.0 26420.0 26989.0 20100.0 False True 30029.455357378618 27243.292454858914 24495.462736067773 27615.937195989703 19793.4755646131 28377.474159559097 25116.792743595026 25726.502994303915 27383.663066828354 23743.970888487547 1.2647191785405463 1.1473772682255114 1.0316497965361215 1.1630715572254813 0.8336211182860793 1.1951444134105698 1.0578177029257183 1.083496232164672 1.1532891105466079 1.0 14.535273607792451 -4.877807144002102 2.5385627325279745 1.0673043460509317 1.2864963102354061 0.28976419952641275 0.09698677526709902 0.5118432689464659 5.004023826358567 0.024282826576497177 0.22428552141970295 1.3249297626218345e-05 4.877807144002102 0.2191919641844744 STGGAPTFNVTVTK ddPTM_PC-9_Lapatinib_30min_R1 2 STGGAPTFNVTVTK 14 0 P07737;K7EJ44 P07737 PFN1 Profilin-1 0 ; 267.93 6.9049e-56 85789000.0 290810.0 279930.0 270060.0 287640.0 288420.0 264830.0 290850.0 267310.0 246440.0 264270.0 False True 286662.996071978 279281.8392838473 247856.7092617465 308794.00513891113 271455.7026555371 253503.8382488827 305908.78986002 279730.19846313196 218683.33207175267 309948.71738235996 0.9248723417633758 0.901058219057957 0.7996700594698208 0.9962745054949708 0.8758084400157818 0.8178896186111797 0.9869658195186005 0.9025047782922433 0.7055468205147621 1.0 18.241670008328484 STGHT(ph)PTKPSGSSVSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STGHTPTKPSGSSVSEK 17 1 Q8NI08-2;Q8NI08;Q8NI08-7 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 1 S(0.004)T(0.004)GHT(0.99)PT(0.001)KPSGSSVSEK 76.817 0.030797 0.0 7828.8 8573.8 13426.0 14649.0 17443.0 15863.0 16443.0 15547.0 18326.0 11257.0 True False 9154.06121415177 9424.950201729793 13746.12675838854 13828.264022698793 14025.1693656232 15031.11635478448 14885.400002989107 15138.907723408136 18593.98308061419 13297.804989637028 0.6883888898420096 0.7087598448822682 1.0337139677639196 1.0398907213239441 1.0546980781078537 1.1303456748311635 1.1193877496766789 1.1384516268065201 1.3982746096144794 1.0 13.698900505583422 -4.891433106202062 0.6485667281250664 1.1710857320271522 0.34839947522142567 0.7304255193980949 0.10213293071476354 1.476595595392064 0.5176412714128972 0.04773647504214307 0.8844835106308722 1.2840055288953975e-05 4.891433106202062 -0.8226862568057265 STGHT(ph)PTKPSGSSVSEK ddPTM_PC-9_Lapatinib_30min_R1 1 STGHTPTKPSGSSVSEK 17 1 Q8NI08-2;Q8NI08;Q8NI08-7 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 1 S(0.002)T(0.002)GHT(0.973)PT(0.022)KPSGSSVSEK 63.446999999999996 0.018347 5737300.0 22343.0 18039.0 22020.0 20765.0 23766.0 22562.0 15867.0 17170.0 24920.0 14719.0 True False 22024.384722795614 17997.231803812865 20209.600599658083 22292.127370009377 22368.130605753744 21597.07585459081 16688.515622172737 17967.780882166695 22113.247180766433 17263.15953816532 1.2758026521219477 1.042522474754674 1.1706779720698741 1.2913121332584592 1.295714759300137 1.2510500066250378 0.9667127031571386 1.040816476407091 1.2809501720631475 1.0 14.075408913179128 -7.240723594826441 24.716185754163604 1.0755211970516014 1.217339430325088 0.32623062463528973 0.10481197395290609 938.5340534845726 1119774.5160516885 0.0418759351886704 0.032399593380387025 5.744819728830485e-08 7.240723594826441 0.14181823327348653 STGS(ph)PTQETQAPFIAK ddPTM_PC-9_AZD4547_30min_R2 4 STGSPTQETQAPFIAK 16 0 O15231-3;O15231-2 O15231-3 ZNF185 Zinc finger protein 185 1 STGS(0.97)PT(0.03)QETQAPFIAK;S(0.001)T(0.001)GS(0.94)PT(0.057)QETQAPFIAK;S(0.066)T(0.066)GS(0.747)PT(0.116)QET(0.005)QAPFIAK;S(0.019)T(0.019)GS(0.696)PT(0.139)QET(0.128)QAPFIAK 235.02 5.813899999999999e-37 457245700.0 1085388.5 918566.4 1302761.0 1654207.0 1621633.0 1470961.0 1176752.2 1591027.0 1265886.0 1371673.0 True False 1430519.4655167214 1215475.0252550163 1285485.5379310856 1272855.1333933808 1396497.2493731142 1378981.5761361031 1281480.8661289273 1345170.3353132978 1332798.1496025093 1323651.1457747659 1.0807375267139612 0.9182744480182266 0.9711664149836542 0.9616243203176824 1.0550342164027742 1.0418013692942871 0.9681409412287743 1.0162574478987334 1.0069104339590849 1.0 20.33609151278568 -6.233543914978526 24.969764946184956 1.0145316594840823 0.9774892133290085 0.10657840161348398 0.04389384996772263 1468.2074088606446 1314221.9620690902 0.012734089113741513 0.016434196119786172 5.840581453298907e-07 6.233543914978526 -0.037042446155073794 STGS(ph)PTQETQAPFIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STGSPTQETQAPFIAK 16 0 O15231-3;O15231-2 O15231-3 ZNF185 Zinc finger protein 185 1 S(0.042)T(0.042)GS(0.916)PTQETQAPFIAK;S(0.021)T(0.021)GS(0.919)PT(0.037)QET(0.002)QAPFIAK;S(0.001)T(0.012)GS(0.921)PT(0.056)QET(0.01)QAPFIAK;S(0.014)T(0.014)GS(0.745)PT(0.226)QETQAPFIAK 149.6 8.0421e-06 270095000.0 760434.0 644010.0 813962.0 897830.0 1047971.0 1045985.0 966272.0 1032401.0 865333.0 746341.0 True False 889160.4569438852 707943.0566861856 833369.9410480731 847527.495904133 842628.6054727687 991131.7052486453 874739.7209565329 1005301.5676692799 877986.8580758024 881646.7152678946 1.0085223951338689 0.8029781594219088 0.9452424952265011 0.9613005767810361 0.955744053576755 1.1241823829032052 0.9921658027056076 1.1402544242041575 0.995848839304097 1.0 19.74984114355886 -6.603844808532646 6.099639297344671 1.055331640505276 0.925896018327155 0.42261531547488473 0.06795188499459469 0.1860678620842537 11.01658184280802 0.021610728205677544 0.02161092721161666 2.4897468493611014e-07 6.603844808532646 -0.129435622178121 STGS(ph)PTQETQAPFIAK ddPTM_PC-9_Lapatinib_30min_R1 5 STGSPTQETQAPFIAK 16 0 O15231-3;O15231-2 O15231-3 ZNF185 Zinc finger protein 185 1 S(0.011)T(0.054)GS(0.811)PT(0.123)QETQAPFIAK;S(0.001)T(0.001)GS(0.819)PT(0.176)QET(0.002)QAPFIAK;STGS(0.997)PT(0.003)QETQAPFIAK;S(0.078)T(0.016)GS(0.898)PT(0.008)QETQAPFIAK;S(0.009)T(0.009)GS(0.979)PT(0.003)QETQAPFIAK 237.34 4.052e-37 503094000.0 1197117.0 1074844.5 1250152.0 1023474.0 1296401.0 1214641.0 1153864.0 1029159.0 1239495.0 1048744.0 True False 1180045.8920556295 1072355.763598501 1147369.3282862767 1098743.6921691778 1220149.242002431 1162693.6358964646 1213605.4320200882 1076977.4842696458 1099890.0206390093 1230018.0030364606 0.959372862139035 0.8718211936339552 0.9328069389666209 0.8932744800944254 0.991976734478953 0.9452655432897754 0.9866566416297519 0.8755786351183362 0.8942064408193918 1.0 20.230248000906045 -9.59927927822418 14.387144829748129 0.9999999986062337 0.9279487816977308 0.214985709230318 0.04134117495312625 0.0 0.0 0.04079683980333317 0.009894687041208562 2.5160584261651517e-10 9.59927927822418 -0.07205121690850291 STGSAT(ph)SLASQGER ddPTM_PC-9_AZD4547_30min_R2 1 STGSATSLASQGER 14 0 H0Y2V6;Q5SW79-2;Q5SW79-3;Q5SW79 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 S(0.025)T(0.001)GS(0.317)AT(0.605)S(0.046)LAS(0.005)QGER 88.78 0.016314 0.0 31665.0 29221.0 27459.0 38973.0 33958.0 32965.0 25570.0 28043.0 20414.0 28109.0 True False 41733.811327084186 38666.1168022005 27094.875718608117 29988.376976847692 29243.517857747196 30903.69333879466 27845.68046434637 23709.598714032367 21493.042363993012 27124.91246571374 1.5385786545794864 1.4254835605856793 0.9988926509110918 1.1055658525996503 1.0781055199610838 1.1393103435027616 1.0265721778657788 0.8740894092838686 0.7923727824434645 1.0 14.727330861420503 -1.5228787452838095 0.4110227289307745 0.9323166805868943 12.235582392326805 0.7806313553863807 0.10171102443996938 36.655079682205525 0.4773636146609833 0.07693405914028037 338.3899614076947 0.029999999999760166 1.5228787452838095 11.303265711739911 STGSPT(ph)QETQAPFIAK ddPTM_PC-9_AZD4547_30min_R2 1 STGSPTQETQAPFIAK 16 0 O15231-3;O15231-2 O15231-3 ZNF185 Zinc finger protein 185 1 S(0.001)T(0.004)GS(0.364)PT(0.622)QET(0.008)QAPFIAK 178.02 1.8599e-05 89661000.0 52512.0 44028.0 65216.0 82680.0 78471.0 64025.0 52395.0 77321.0 52664.0 53324.0 True False 69209.72368254686 58259.18998553383 64351.193228622586 63619.403393266315 67576.65615805646 60021.50662873738 57058.053497435605 65372.81610982052 55447.711524313105 51457.14299056241 1.3449974028919638 1.1321885864557026 1.2505784326274203 1.2363570866135056 1.3132609435865974 1.1664368276284933 1.1088461228385813 1.270432292010661 1.0775513038973539 1.0 15.651083737364058 -8.70800888097084 0.4547625591184214 0.9858257871149289 1.249469746358563 0.5224195658182649 0.07272150318975365 1.202096257831424 0.5725664795859985 0.10444983981641039 0.04550134640934487 1.958804617126548e-09 8.70800888097084 0.26364395924363404 STGSPT(ph)QETQAPFIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STGSPTQETQAPFIAK 16 0 O15231-3;O15231-2 O15231-3 ZNF185 Zinc finger protein 185 1 STGS(0.086)PT(0.809)QET(0.104)QAPFIAK;S(0.002)T(0.002)GS(0.469)PT(0.506)QET(0.022)QAPFIAK 98.156 0.0051086000000000005 145349000.0 229269.0 202010.0 262013.0 224600.0 261370.0 230701.0 263710.0 264204.0 197027.0 192133.0 True False 268079.7134308409 222064.2177624195 268260.38360983634 212016.39016302503 210156.42476024386 218602.6334341003 238729.47970493583 257268.92494727776 199908.14713653654 226965.191976009 1.1811490171549206 0.9784064940931226 1.1819450430892169 0.934136148002095 0.9259412112076556 0.963154885253098 1.0518330041117951 1.1335170944383048 0.8807876899364706 1.0 17.792111533124206 -1.522899042708633 0.8280853425199806 1.000055301147978 50.02127924088831 0.24568267586706805 0.08982324139441732 940.0233998452928 2.884444118164857 0.031666384913046276 86662.20586900476 0.029998597936089492 1.522899042708633 49.02122393974033 STGTEPPGEVRLADS(ph)AASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STGTEPPGEVRLADSAASR 19 1 O43586-2 O43586-2 1 STGTEPPGEVRLADS(0.994)AAS(0.006)R 74.33800000000001 0.021146 23407000.0 25597.0 21562.0 23185.0 25052.0 31062.0 23367.0 28409.0 26074.0 28000.0 21230.0 True False 29930.06653620515 23702.53286170633 23737.81832960215 23648.417659679857 24975.624080432714 22141.593384747463 25717.893856651306 25389.585127686616 28409.44702920426 25078.830943412464 1.1934394630969423 0.9451211228780324 0.9465281050446028 0.942963318866012 0.9958847019937801 0.8828798054704964 1.0254821652046229 1.0123910953016644 1.1328058749351975 1.0 14.614182477631537 -7.8326155085512505 2.5772914060000884 1.0648732308593418 0.9795689924573144 0.10209878555354457 0.0837502940348355 0.5603484651666955 7.351970932513273 0.05553976305739184 0.02299892050300691 1.4702273295819136e-08 7.8326155085512505 -0.08530423840202739 STGTEPPGEVRLADS(ph)AASR ddPTM_PC-9_Lapatinib_30min_R1 1 STGTEPPGEVRLADSAASR 19 1 O43586-2 O43586-2 1 STGTEPPGEVRLADS(1)AASR 94.454 0.0036792 5789500.0 15470.0 11526.0 13356.0 13223.0 16221.0 14384.0 11636.0 12766.0 13752.0 12190.0 True False 15249.394963149442 11499.312255155326 12257.921235650932 14195.463530634914 15266.912671713015 13768.829850741706 12238.45514461474 13359.15496457426 12203.104945020072 14297.025257846 1.0666131372175338 0.8043150269210492 0.8573756438545818 0.9928963035750845 1.0678384066877658 0.9630555729196584 0.8560140955125229 0.9344010186484737 0.8535415392319591 1.0 13.803427380245568 -10.697471489601583 20.877202559828085 0.9999999999884589 0.9312954948221939 0.050946633765554195 0.08664236139994294 0.0 0.0 0.08671801985429857 0.021032209147275438 2.0069128347416977e-11 10.697471489601583 -0.06870450516626503 STIFIS(ph)PSSVK ddPTM_PC-9_AZD4547_30min_R2 2 STIFISPSSVK 11 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 S(0.008)T(0.001)IFIS(0.989)PS(0.002)SVK;ST(0.01)IFIS(0.929)PS(0.058)S(0.002)VK 169.09 0.0016876999999999999 65450000.0 82153.0 87533.0 104325.0 118627.0 111456.0 104756.0 93953.0 124996.0 86149.0 100334.0 True False 108275.94511144637 115826.3304488901 102941.58233525584 91279.37791888003 95982.25827060103 98205.59075985967 102314.6349889221 105680.74032233295 90702.66026333066 96821.33719929273 1.1183066485497508 1.196289307701652 1.0632117394058034 0.9427609714891111 0.9913337395148285 1.0142969886660174 1.056736437943655 1.0915025900210862 0.9368044574372315 1.0 16.56303739894411 -5.462121733119665 5.032936744274717 1.00990233393618 1.1543548280237315 0.6195952644634076 0.04727483512698985 0.1397327075235307 7.175022168155897 0.012940182402470017 0.027152870448484984 3.450470088040558e-06 5.462121733119665 0.14445249408755156 STIFIS(ph)PSSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 STIFISPSSVK 11 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 ST(0.001)IFIS(0.994)PS(0.004)S(0.001)VK;S(0.017)T(0.031)IFIS(0.75)PS(0.149)S(0.053)VK;STIFIS(0.933)PS(0.057)S(0.011)VK 153.81 0.0004614 48655000.0 170709.0 164411.0 166194.0 171359.0 189865.0 166078.0 176753.0 156441.0 154662.0 109070.0 True False 199606.6620435619 180732.6375255543 170156.6952542551 161758.31078337374 152662.31620730672 157368.57731639006 160009.67625909692 152334.5895129409 156923.63915824227 128843.52760235511 1.5492176111445843 1.4027296589033373 1.3206460457944247 1.2554632257710474 1.18486600800362 1.221392958147426 1.241891457310364 1.1823224056941795 1.2179396363824324 1.0 16.975260540307076 -1.5228787452803376 0.31649559233925906 1.1342386189126208 4.986412865334337 0.8417362175862284 0.05491239116957996 21.75909133626487 0.31066385003039343 0.052100069341307696 48.33331912625251 0.029999999999999995 1.5228787452803376 3.8521742464217166 STIFIS(ph)PSSVK ddPTM_PC-9_Lapatinib_30min_R1 2 STIFISPSSVK 11 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 S(0.074)T(0.074)IFIS(0.819)PS(0.032)S(0.001)VK;S(0.031)T(0.031)IFIS(0.905)PS(0.032)S(0.002)VK 166.45 0.00014078 42614000.0 138457.0 135844.0 150328.0 135096.0 141652.0 142346.0 128762.0 117367.0 134762.0 98114.0 True False 136482.57779009573 135529.46156423024 137968.61212286132 145031.41050704478 133320.30785854702 136258.19340473277 135428.6663226953 122820.29928929891 119583.68445322817 115072.87417131299 1.1860534359027948 1.1777707173843839 1.1989672902187414 1.2603440346082908 1.1585728506274071 1.1841035029843825 1.1768947920869512 1.0673262502025636 1.0391995969023924 1.0 16.81218826524251 -7.895028647776335 1.493415289341813 1.0069993621094762 1.1976723416860107 0.8852705824524627 0.02622785068700009 0.13090370030140686 0.5308181476344669 0.022996077557762562 0.00815862923670544 1.2734190785029506e-08 7.895028647776335 0.1906729795765345 STIGVMVT(ph)ASHNPEEDNGVK ddPTM_PC-9_AZD4547_30min_R2 1 STIGVMVTASHNPEEDNGVK 20 0 D6RC77;D6RCQ8;D6RF77;A0A494C163;A0A494C099;A0A494C0G1;H0Y987;O95394;O95394-3;O95394-4 D6RC77 PGM3 Phosphoacetylglucosamine mutase 1 STIGVMVT(0.589)AS(0.41)HNPEEDNGVK 61.903 0.023005 12059000.0 32341.0 25216.0 33455.0 41306.0 37058.0 37842.0 29753.0 39316.0 34919.0 40174.0 True False 42624.765265410715 33366.57887424412 33011.364840891314 31783.53987133839 31913.13636764225 35475.73375782398 32400.959360801615 33240.615591801725 36764.7470514486 38767.52048801392 1.0994968140557086 0.8606838522097472 0.8515211812707422 0.8198496956018937 0.8231926098422803 0.9150890567992944 0.8357759008812362 0.8574346559532742 0.9483388823594087 1.0 15.242560844996056 -10.29182810728592 11.008301387328734 0.9999978012265441 0.8822851441023302 0.13827537222963138 0.0801273418479845 0.0 0.0 0.07664216529104373 0.018588455463001242 5.107070966217591e-11 10.29182810728592 -0.11771265712421397 STIGVMVT(ph)ASHNPEEDNGVK ddPTM_PC-9_Lapatinib_30min_R1 2 STIGVMVTASHNPEEDNGVK 20 0 D6RC77;D6RCQ8;D6RF77;A0A494C163;A0A494C099;A0A494C0G1;H0Y987;O95394;O95394-3;O95394-4 D6RC77 PGM3 Phosphoacetylglucosamine mutase 1 STIGVMVT(0.565)AS(0.435)HNPEEDNGVK;STIGVMVT(0.812)AS(0.188)HNPEEDNGVK 110.1 0.00015729 44176100.0 136808.0 171357.0 167064.0 152575.0 190858.0 172996.0 159979.0 168668.0 183223.0 145796.0 True False 134857.09283248527 170960.2333946431 153328.6428056895 163795.87447527953 179632.1076812653 165597.36435337245 168261.9298367414 176504.93103280684 162586.49631627472 170996.6443390418 0.788653446117333 0.9997870663220354 0.8966763260083557 0.9578894083471894 1.0505007766415675 0.9684246436148537 0.9840072036917976 1.0322128350240811 0.9508168826629605 1.0 17.38360848818585 -4.158150302049576 1.6880398468080853 0.9846562802043554 1.4344406616617888e-33 0.6351356131164766 0.042971755267923684 4.7246973670996235 2.890699169023014 0.011818245436123708 12.747558359964248 6.947838229260096e-05 4.158150302049576 -0.9846562802043554 STIGVMVTAS(ph)HNPEEDNGVK ddPTM_PC-9_AZD4547_30min_R2 8 STIGVMVTASHNPEEDNGVK 20 0 D6RC77;D6RCQ8;D6RF77;A0A494C163;A0A494C099;A0A494C0G1;H0Y987;O95394;O95394-3;O95394-4 D6RC77 PGM3 Phosphoacetylglucosamine mutase 1 S(0.001)T(0.001)IGVMVT(0.187)AS(0.812)HNPEEDNGVK;STIGVMVT(0.001)AS(0.999)HNPEEDNGVK;STIGVMVT(0.041)AS(0.959)HNPEEDNGVK;STIGVMVT(0.025)AS(0.975)HNPEEDNGVK;STIGVMVT(0.303)AS(0.697)HNPEEDNGVK;S(0.006)T(0.006)IGVMVT(0.034)AS(0.954)HNPEEDNGVK;STIGVMVT(0.004)AS(0.995)HNPEEDNGVK;STIGVMVT(0.072)AS(0.928)HNPEEDNGVK 140.2 0.00010809 416188200.0 329988.0 364666.0 406445.0 516538.0 449796.0 426768.0 397773.0 497131.0 434747.0 435820.0 True False 434917.3198232063 482537.15306769934 401055.2737335543 397458.14453254687 387349.5894441148 400082.1294952444 433174.02641159436 420310.82688391523 457726.83886640833 420562.0744532828 1.0341334757504819 1.1473624998045346 0.95361730906172 0.9450641621673321 0.9210283403410944 0.9513033956172542 1.029988324493374 0.9994025909975497 1.0883692721495122 1.0 18.681959230675908 -10.813075279969416 14.737553325035822 0.9999998864730254 1.0046639627538647 0.0 0.0670127401085773 0.0 0.0 0.07027232519994968 0.01704354231512625 1.5378880419370518e-11 10.813075279969416 0.004664076280839313 STIGVMVTAS(ph)HNPEEDNGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 STIGVMVTASHNPEEDNGVK 20 0 D6RC77;D6RCQ8;D6RF77;A0A494C163;A0A494C099;A0A494C0G1;H0Y987;O95394;O95394-3;O95394-4 D6RC77 PGM3 Phosphoacetylglucosamine mutase 1 S(0.001)T(0.004)IGVMVT(0.024)AS(0.972)HNPEEDNGVK;S(0.001)T(0.002)IGVMVT(0.197)AS(0.8)HNPEEDNGVK;STIGVMVT(0.001)AS(0.999)HNPEEDNGVK;STIGVMVT(0.016)AS(0.984)HNPEEDNGVK;STIGVMVT(0.002)AS(0.998)HNPEEDNGVK;STIGVMVT(0.004)AS(0.996)HNPEEDNGVK;S(0.001)T(0.001)IGVMVT(0.221)AS(0.777)HNPEEDNGVK 103.92 0.00011492 438832000.0 276134.0 302743.0 262463.0 315553.0 321465.0 255443.0 296186.0 265571.0 234436.0 231716.0 True False 322878.032304898 332797.32428121485 268721.1133164708 297873.58844662993 258476.24090581143 242047.11939829847 268129.1178790574 258600.0426457343 237864.1829906623 273724.27653715265 1.1795739727202228 1.2158122344550035 0.9817218871341039 1.0882249547427318 0.9442941787106282 0.8842734830114543 0.9795591434969569 0.9447464650094142 0.8689919140525226 1.0 18.0623638670739 -5.392673321029077 0.8819555436650653 0.9321366870408447 1.2541819555523168 0.7227173989910644 0.0584733941624745 0.5400572300913649 0.5931247253927808 0.022412086773927465 0.14119663453872353 4.048803306487457e-06 5.392673321029077 0.3220452685114721 STIGVMVTAS(ph)HNPEEDNGVK ddPTM_PC-9_Lapatinib_30min_R1 7 STIGVMVTASHNPEEDNGVK 20 0 D6RC77;D6RCQ8;D6RF77;A0A494C163;A0A494C099;A0A494C0G1;H0Y987;O95394;O95394-3;O95394-4 D6RC77 PGM3 Phosphoacetylglucosamine mutase 1 STIGVMVT(0.013)AS(0.986)HNPEEDNGVK;STIGVMVT(0.002)AS(0.998)HNPEEDNGVK;S(0.001)T(0.004)IGVMVT(0.223)AS(0.772)HNPEEDNGVK;STIGVMVT(0.001)AS(0.999)HNPEEDNGVK;STIGVMVTAS(1)HNPEEDNGVK;STIGVMVT(0.045)AS(0.954)HNPEEDNGVK;STIGVMVT(0.436)AS(0.564)HNPEEDNGVK 118.24 1.0422000000000001e-05 334962000.0 475544.0 519682.0 533450.0 448729.0 510787.0 531579.0 486854.0 504238.0 500618.0 467281.0 True False 468762.65535591054 518478.70825816813 489591.80017654825 481730.02757606143 480743.5129058797 508844.6053411724 512060.91792508285 527666.7382913205 444233.12909875315 548049.8982372055 0.8553284233126925 0.9460428875652516 0.8933343510350301 0.8789893568551679 0.87718931150646 0.9284640084376691 0.9343326576140591 0.9628078391922942 0.8105705895167987 1.0 19.06394772649511 -6.7757791474977225 24.61805879163255 0.9253541208124116 0.8928344216670432 0.11946444415448809 0.04991480749596509 508.19428060776556 872445.6511648027 0.01687229626661866 0.014950221430922788 1.6757948541508136e-07 6.7757791474977225 -0.03251969914536845 STKPVVFS(ph)PTLMLTDEEK ddPTM_PC-9_AZD4547_30min_R2 1 STKPVVFSPTLMLTDEEK 18 1 P40818;P40818-2;A0A075B720 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 S(0.001)T(0.004)KPVVFS(0.705)PT(0.245)LMLT(0.045)DEEK 60.618 0.03911 8072000.0 58500.0 50089.0 52737.0 60874.0 53097.0 59181.0 52699.0 55081.0 50602.0 49222.0 True False 77101.78312440937 66279.28970621881 52037.67292225633 46840.43979392465 45725.398070934774 55480.40271449133 57389.108908509574 46569.49708546219 53276.71841396953 47498.75276201077 1.6232380566016658 1.395390107153058 1.0955587230466346 0.9861404156992384 0.9626652367071349 1.1680391481534698 1.20822349159469 0.9804362088999568 1.1216445762462197 1.0 15.53560201072596 -5.066449847384574 2.300588910008241 1.0637910964857562 1.6325113261241448 0.8425939337156714 0.07981162103537538 0.141042134613001 1.2838420485007456 0.023159540129525452 0.12624639472578186 8.581242057545812e-06 5.066449847384574 0.5687202296383886 STKPVVFS(ph)PTLMLTDEEK ddPTM_PC-9_Lapatinib_30min_R1 1 STKPVVFSPTLMLTDEEK 18 1 P40818;P40818-2;A0A075B720 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 STKPVVFS(0.858)PT(0.074)LMLT(0.068)DEEK 88.23899999999999 0.00073672 8705700.0 27794.0 28072.0 24222.0 25591.0 34052.0 42025.0 40083.0 43465.0 44237.0 36203.0 True False 27397.652463204635 28007.001008738553 22230.560659623887 27473.047509073436 32049.128308807813 40227.68871505981 42158.301612374744 45484.54257678366 39254.563223738536 42460.64031253475 0.6452482172087407 0.6595991205641485 0.5235568869426878 0.6470238627316026 0.7547961611720356 0.9474112594384086 0.9928795539131153 1.0712165959342874 0.9244929641852397 1.0 15.373838507004542 -6.635082565911239 1.9108571586543108 1.0037962860031455 0.6122177622486623 0.9306653446174202 0.04788803286703502 0.07929442715334564 0.5931427868558575 0.01886737535101233 0.018914089704111063 2.3169541202772114e-07 6.635082565911239 -0.3915785237544832 STKPVVFSPT(ph)LMLTDEEK ddPTM_PC-9_Lapatinib_30min_R1 1 STKPVVFSPTLMLTDEEK 18 1 P40818;P40818-2;A0A075B720 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 S(0.004)T(0.004)KPVVFS(0.118)PT(0.687)LMLT(0.187)DEEK 65.265 0.0109 5213800.0 17070.0 16451.0 16315.0 12212.0 24938.0 23586.0 29725.0 29220.0 25802.0 25625.0 True False 16826.578669745395 16412.908720246436 14973.643677721237 13110.111218037766 23471.195869994404 22577.281761651393 31264.015054457963 30577.66787285446 22895.907052894694 30054.247106833765 0.5598735716097626 0.5461094620638309 0.49822055513466895 0.4362149273423913 0.78096103311327 0.7512176791984168 1.0402528116350358 1.0174158668543616 0.7618193519041306 1.0 14.875281258905526 -6.645244254864334 1.6782961278582451 0.9469204303252721 0.5128203700123335 0.8002344909790151 0.09562738171492428 0.1546376697347344 0.8975555542033575 0.03881475644384152 0.03868926869983009 2.2633709898569228e-07 6.645244254864334 -0.4341000603129386 STKPVVFSPTLMLT(ph)DEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STKPVVFSPTLMLTDEEK 18 1 P40818;P40818-2;A0A075B720 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 S(0.002)T(0.002)KPVVFS(0.248)PT(0.355)LMLT(0.393)DEEK;STKPVVFS(0.008)PT(0.004)LMLT(0.988)DEEK 64.76100000000001 0.010103000000000001 14548600.0 73046.0 85159.0 76992.0 82660.0 98350.0 79532.0 107207.0 89242.0 83350.0 68865.0 True False 85411.24507573727 93613.0227237754 78827.78127378605 78028.82818733566 79079.02351138218 75361.20191191573 97051.57684853447 86899.49205971508 84568.83606729186 81349.67936495994 1.0499272491604532 1.1507485149855143 0.9689992866491843 0.959178066790824 0.9720877098557341 0.9263859734937856 1.193017324790316 1.0682216910758424 1.0395718425378149 1.0 16.311849039159682 -7.245293777838079 24.995083870632115 1.080887872678221 1.006045188606462 0.17731637070119244 0.07410508350271439 1495.3253767929134 2314923.8327438273 0.03026169568422516 0.02335224583974563 5.684682612680104e-08 7.245293777838079 -0.07484268407175887 STLEPVEK ddPTM_PC-9_Lapatinib_30min_R1 1 STLEPVEK 8 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;P17066;P48741 A0A0G2JIW1;P17066 HSPA1B;HSPA1A;HSPA6;HSPA7 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7 0 90.65700000000001 0.0429 17640000.0 411590.0 362030.0 372760.0 329360.0 336970.0 322210.0 289040.0 243230.0 322550.0 216140.0 False True 405720.6511236386 361191.74177805666 342113.11169521144 353582.23311275203 317150.08710850944 308429.82940819557 304005.076916418 254531.35375477056 286221.0223979221 253499.51101155355 1.6004790285577608 1.4248222426022545 1.349561229250731 1.3948043990374288 1.2510875695300845 1.2166880645151954 1.1992333859080406 1.0040703934264 1.1290791893672618 1.0 17.9516234387783 -4.80839733870893 0.24868536625158785 0.9638804744447326 2.0454216874363933 0.9107610350678281 0.053860988148739325 2.7246445321279347 0.14646206451152413 0.08066777039203515 0.9121853302676598 1.5545427200348794e-05 4.80839733870893 1.0815412129916608 STLES(ph)EKPGS(ph)PEAAETSPPSNIIDHCEK ddPTM_PC-9_Lapatinib_30min_R1 1 STLESEKPGSPEAAETSPPSNIIDHCEK 28 1 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 2 S(0.11)T(0.11)LES(0.592)EKPGS(0.725)PEAAET(0.23)S(0.23)PPS(0.004)NIIDHCEK 42.708 0.023535 10257000.0 17601.0 21444.0 25174.0 22177.0 24020.0 21580.0 23603.0 19807.0 22953.0 22528.0 True False 17350.006512371907 21394.347735515432 23104.290894450154 23807.970560303274 22607.19082513697 20657.073705437015 24825.04784963403 20727.305529008492 20367.791434194707 26421.934783326866 0.6566516288322817 0.8097191939560758 0.8744359973604107 0.9010684022779024 0.8556220810673892 0.7818153316490785 0.9395620742088681 0.7844734194896327 0.7708667666172377 1.0 14.68944849337529 -14.50448070826134 0.019545622633310732 2.016678333081483 8.519958466204288e-07 0.3039122014677115 0.0775454160686388 5381.3175944728455 7.95735289266006 549.6264923780781 304.7143981329188 3.1298194977803964e-15 14.50448070826134 -2.0166774810856363 STLESEKPGS(ph)PEAAET(ph)SPPSNIIDHCEK ddPTM_PC-9_AZD4547_30min_R2 1 STLESEKPGSPEAAETSPPSNIIDHCEK 28 1 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 2 S(0.027)T(0.027)LES(0.073)EKPGS(0.844)PEAAET(0.515)S(0.515)PPS(0.001)NIIDHCEK 52.465 0.011427 5613000.0 21030.0 18695.0 21858.0 24407.0 28964.0 20900.0 23134.0 23274.0 20491.0 20809.0 True False 27717.10254882616 24737.793149349392 21568.148638236515 18780.343234391028 24942.848555032386 19593.11969606576 25192.88118350369 19677.538083314525 21574.112426794403 20080.483243766656 1.380300574062631 1.2319321626399828 1.0740851391079773 0.9352535497481509 1.2421438394803122 0.9757294910792458 1.2545953639499197 0.9799334928566915 1.074382133382741 1.0 14.293506368210483 -5.001733154340571 2.5038926375819015 1.0712346349826667 1.3874401489368873 0.49368806747712024 0.1021786815217635 0.279941251125639 3.0316387355481162 0.025753998978531745 0.15467354661985744 9.960172170536923e-06 5.001733154340571 0.3162055139542206 STLESEKPGS(ph)PEAAETSPPSNIIDHCEK ddPTM_PC-9_AZD4547_30min_R2 3 STLESEKPGSPEAAETSPPSNIIDHCEK 28 1 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 S(0.019)T(0.019)LES(0.05)EKPGS(0.395)PEAAET(0.395)S(0.123)PPSNIIDHCEK;S(0.227)T(0.047)LES(0.116)EKPGS(0.411)PEAAET(0.146)S(0.052)PPS(0.001)NIIDHCEK;S(0.093)T(0.093)LES(0.087)EKPGS(0.505)PEAAET(0.198)S(0.024)PPSNIIDHCEK 61.708999999999996 0.00047407 116772000.0 214972.0 210913.0 264083.0 344292.0 326937.0 339648.0 277533.0 278604.0 261741.0 290089.0 True False 283328.624304625 279086.50262148865 260581.08687123304 264920.7986583745 281547.4408934067 318409.7568674327 302232.8993473387 235552.15348301837 275576.094905158 279933.0724062192 1.0121298704337385 0.9969758136205426 0.9308692418204023 0.9463719180488259 1.0057669802046285 1.1374495843970118 1.0796612802818795 0.8414588224902616 0.984435645764861 1.0 18.094722417145448 -7.749061195185311 24.999990957822007 0.9347103903581772 1.0132733564690775 0.19282847189841856 0.06844546421009233 370.7604789687881 748821.7219174315 0.03543236157792921 0.020270981370488026 1.7821276352801885e-08 7.749061195185311 0.0785629661109003 STLESEKPGS(ph)PEAAETSPPSNIIDHCEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STLESEKPGSPEAAETSPPSNIIDHCEK 28 1 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 S(0.021)T(0.021)LES(0.051)EKPGS(0.606)PEAAET(0.13)S(0.169)PPS(0.002)NIIDHCEK;S(0.009)T(0.009)LES(0.063)EKPGS(0.551)PEAAET(0.164)S(0.202)PPS(0.003)NIIDHCEK;S(0.009)T(0.009)LES(0.023)EKPGS(0.808)PEAAET(0.075)S(0.075)PPS(0.002)NIIDHCEK;STLES(0.001)EKPGS(0.999)PEAAETSPPSNIIDHCEK 144.48 4.0236e-17 53169000.0 107665.0 113462.0 112762.0 156403.0 164194.0 139309.0 160852.0 132370.0 130578.0 122923.0 True False 125890.5580193198 124725.7575157648 115450.67373226628 147640.24697536763 132021.36437649105 132003.39080052156 145614.93409236797 128895.42775760846 132487.45622069415 145207.96684206743 0.8669672935799877 0.8589456916742061 0.7950712088533952 1.0167503215298483 0.9091881612809956 0.9090643831139956 1.0028026509781187 0.8876608533318218 0.9123979840912689 1.0 17.14776108347457 -5.751847974502114 24.99998847481137 0.9425962166384794 0.8421898300481803 0.5275052790711765 0.046587576664937375 166.6164470140721 434281.3540592639 0.012479116920158332 0.02126189896755848 1.7707286963342675e-06 5.751847974502114 -0.1004063865902991 STLESEKPGS(ph)PEAAETSPPSNIIDHCEK ddPTM_PC-9_Lapatinib_30min_R1 2 STLESEKPGSPEAAETSPPSNIIDHCEK 28 1 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 STLES(0.005)EKPGS(0.992)PEAAET(0.001)S(0.002)PPSNIIDHCEK;S(0.055)T(0.021)LES(0.048)EKPGS(0.835)PEAAET(0.029)S(0.012)PPSNIIDHCEK 69.771 6.971399999999999e-05 91452100.0 200931.0 195124.0 199855.0 207856.0 235309.0 204314.0 205127.0 197866.0 234271.0 205090.0 True False 198065.6870937677 194672.20236638293 183423.69336260975 223142.42362728907 221468.58725529353 195575.9664991964 215747.47236588062 207059.57670534594 207884.93299700366 240539.53323475292 0.8234225968189055 0.8093147922441253 0.7625511320153708 0.92767463471177 0.9207159599796545 0.8130720296539586 0.8969314501634263 0.8608130809968254 0.8642443518592837 1.0 17.875914498222578 -14.522878745224855 0.09927810686182631 1.4451123653380693 0.7571613538795203 0.500558522662921 0.04700260288702647 173.92911823563065 1.1723157052005397 16.216543054823 0.8678848632869175 3.0000000003832624e-15 14.522878745224855 -0.687951011458549 STLESEKPGSPEAAET(ph)S(ph)PPSNIIDHCEK ddPTM_PC-9_AZD4547_30min_R2 1 STLESEKPGSPEAAETSPPSNIIDHCEK 28 1 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 2 S(0.016)T(0.016)LES(0.029)EKPGS(0.14)PEAAET(0.869)S(0.927)PPS(0.004)NIIDHCEK 49.559 0.023167 4961200.0 25282.0 25242.0 25085.0 30799.0 32204.0 30988.0 28697.0 28559.0 24300.0 31728.0 True False 33321.15010173196 33400.98286578643 24752.356509752186 23698.766389806588 27733.030481503338 29050.315461324695 31250.977406544695 24145.862770532753 25584.448390566777 30617.21237725161 1.0883143014838725 1.0909217486632827 0.8084457920193618 0.7740340987873415 0.9057986775474308 0.9488230052879958 1.0206996320071244 0.7886368776170156 0.8356230500454005 1.0 14.902055314490614 -5.2485587423211575 24.279747892739536 0.8815777045849345 1.0896180906691089 0.5021007769319937 0.08133540105962038 444.2967583038197 837484.9210273256 0.021976810554274456 0.05728958801291488 5.642106215103787e-06 5.2485587423211575 0.2080403860841744 STLESEKPGSPEAAET(ph)S(ph)PPSNIIDHCEK ddPTM_PC-9_Lapatinib_30min_R1 1 STLESEKPGSPEAAETSPPSNIIDHCEK 28 1 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 2 S(0.012)T(0.012)LES(0.025)EKPGS(0.305)PEAAET(0.762)S(0.762)PPS(0.122)NIIDHCEK 51.473 0.015433 10583000.0 29264.0 29403.0 29363.0 30154.0 32879.0 32824.0 30747.0 27136.0 27697.0 29642.0 True False 28846.68999363964 29334.919160014928 26948.887484457777 32371.62575079521 30945.121862601114 31420.194036481207 32338.929213773565 28396.8376248384 24577.472197660027 34765.58020451775 0.8297485565879049 0.8437920203674003 0.7751600095820003 0.931140097773733 0.8901080229513855 0.9037730379197926 0.9301996119015197 0.8168089661609693 0.706948425801512 1.0 15.085372046490512 -5.756080228695917 24.999800207470557 0.8782426713556951 0.8189893898574357 0.1381485303288188 0.07542073372786035 312.87199288873734 1459491.21566472 0.02118851540054706 0.03537370935493359 1.7535565314597752e-06 5.756080228695917 -0.05925328149825937 STLESEKPGSPEAAET(ph)SPPSNIIDHCEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STLESEKPGSPEAAETSPPSNIIDHCEK 28 1 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 S(0.023)T(0.009)LES(0.025)EKPGS(0.278)PEAAET(0.486)S(0.179)PPSNIIDHCEK 55.788999999999994 0.0019158 24778000.0 22704.0 25500.0 17115.0 31277.0 32242.0 30077.0 23968.0 29223.0 23213.0 19667.0 True False 26547.338775559725 28031.471476370996 17523.086508998953 29524.651091402156 25924.411551133617 28499.709172467577 21697.57752670697 28455.927214327912 23552.446210318536 23232.471416113658 1.1426825110455934 1.2065643372288335 0.7542497823475306 1.2708355715838457 1.1158697276241079 1.2267187877696322 0.9339332496351589 1.2248342720263223 1.0137727402510845 1.0 14.503855012392668 -8.48861028628272 24.015413485669963 0.999999606337233 1.1054326141731323 0.0707079299438731 0.14859029480956412 910.1242464568323 637817.7736022983 0.13716700964424158 0.03541636959965121 3.246307938032333e-09 8.48861028628272 0.10543300783589937 STLESEKPGSPEAAETS(ph)PPSNIIDHCEK ddPTM_PC-9_Lapatinib_30min_R1 1 STLESEKPGSPEAAETSPPSNIIDHCEK 28 1 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 S(0.013)T(0.013)LES(0.013)EKPGS(0.301)PEAAET(0.301)S(0.358)PPS(0.001)NIIDHCEK 53.089 0.0029701999999999997 83531000.0 39996.0 49816.0 51775.0 47327.0 53206.0 54993.0 44199.0 47444.0 47968.0 40036.0 True False 39425.649705631884 49700.65411268592 47518.259357279654 50807.58545824383 50076.52768702074 52641.07758494425 46487.407952632086 49648.421442837294 42565.33871456679 46956.1692553833 0.8396266205449016 1.0584478014459833 1.0119705272131396 1.0820215163190507 1.0664525765435966 1.1210684010154683 0.9900170454663426 1.0573354306824196 0.9064908698804658 1.0 15.51902709588309 -4.757809996241785 24.99776501186334 1.0378211947619667 0.8396263400028794 0.508772018723489 0.05669337000956569 83.58511232256384 575615.3923392128 0.013857702494076876 0.09980266374897463 1.7465861169052585e-05 4.757809996241785 -0.19819485475908727 STLNPQWNES(ph)FTFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STLNPQWNESFTFK 14 0 P17252;J3KRN5 P17252 PRKCA Protein kinase C alpha type 1 STLNPQWNES(0.992)FT(0.008)FK;STLNPQWNES(0.991)FT(0.009)FK 205.33 9.758599999999999e-11 10407000.0 37270.0 33650.0 32409.0 42900.0 52656.0 41547.0 36366.0 40104.0 39172.0 31649.0 True False 43579.074883946 36990.54961489743 33181.75347181696 40496.45208367657 42338.43479425877 39368.20218068659 32921.14921296002 39051.312493700374 39744.81639385678 37386.71316665383 1.165630011113555 0.9894036271658736 0.887527965454118 1.0831776493205183 1.1324460271629737 1.0529998185505136 0.8805574607805652 1.04452382105981 1.0630732960314415 1.0 15.190238022540038 -10.288443858093311 8.270260893561103 1.0000011282725683 1.0284898646886023 0.010044467932562973 0.08828413431145687 0.0 0.0 0.08844919091057096 0.021452079801453274 5.147023390656826e-11 10.288443858093311 0.028488736416034 STLNPQWNES(ph)FTFK ddPTM_PC-9_Lapatinib_30min_R1 2 STLNPQWNESFTFK 14 0 P17252;J3KRN5 P17252 PRKCA Protein kinase C alpha type 1 STLNPQWNES(0.996)FT(0.004)FK;STLNPQWNES(0.971)FT(0.029)FK 142.54 4.0635e-05 10001700.0 136863.0 99736.0 115625.0 99358.0 96897.0 107784.0 97349.0 88435.0 104214.0 79088.0 True False 134911.3085223995 99505.06741976162 106118.7588254073 106665.11876857163 91197.70896683157 103174.32957677591 102389.25488768479 92544.01294783987 92476.32189792919 92758.25542186397 1.4544399084353592 1.0727354343525888 1.144035733992407 1.1499258829681447 0.9831761987336325 1.1122926914433622 1.103829027637692 0.997690313675589 0.9969605559887629 1.0 16.501188065877763 -2.4162927881911602 1.2847452078426462 1.0579054987287548 199.9993617684187 0.7728708415990339 0.06316770274245277 349.8065371863464 1.5214821976444606 0.018622927578414206 204065.93067697936 0.003834486488631499 2.4162927881911602 198.94145626968995 STLPDADRER ddPTM_PC-9_AZD4547_30min_R2 4 STLPDADRER 10 1 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ;;; 119.75 0.006795399999999999 95000300.0 248519.0 226434.0 297972.0 441240.0 401722.0 334029.0 252265.0 361187.0 291657.0 287543.0 False True 327542.87248367775 299624.3623417911 294020.69658855355 339518.93509004376 345949.8345264708 313142.1138257018 274716.0962979406 305373.8484015695 307073.3935904333 277476.207091278 1.1804358864395532 1.0798200158589717 1.059624894223212 1.2235965694109272 1.2467729689438485 1.1285368108073182 0.9900528019239162 1.1005406611353685 1.1066656734622982 1.0 18.082004543618254 -7.017372089163849 24.110285911687384 1.057921957379349 1.1554551086900446 0.39241082190894017 0.0637681942477223 589.592414136565 818279.6150329513 0.026026614573449097 0.020654340801437174 9.607887535881413e-08 7.017372089163849 0.09753315131069562 STLPDADRER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STLPDADRER 10 1 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ;;; 148.94 0.0013697000000000002 60848500.0 195980.0 173103.0 223680.0 247874.0 271274.0 256454.0 235321.0 245234.0 221919.0 185195.0 False True 229155.54321856063 190287.52184212787 229013.3795111237 233986.42339835083 218119.8070567029 243005.10077853518 213029.6913034974 238796.86734690124 225164.1455454994 218769.38749718654 1.047475361339153 0.8698087242419831 1.0468255276989744 1.0695574279164628 0.9970307525750512 1.1107820136931192 0.97376371411305 1.0915460800015828 1.0292305889844624 1.0 17.73905134969784 -5.371062291619889 24.823702637611945 1.042818366706721 0.9585211940995599 0.2444307697401532 0.05691259476945924 26.091772125340917 5881.441573288286 0.013516954643313947 0.028137786553318195 4.255373731839004e-06 5.371062291619889 -0.08429717260716107 STLPDADRER ddPTM_PC-9_Lapatinib_30min_R1 4 STLPDADRER 10 1 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ;;; 117.71 0.0012113 144804000.0 336838.0 328092.0 368324.0 309661.0 342610.0 355713.0 287568.0 292213.0 346944.0 274494.0 False True 332034.62835147674 327332.3231319128 338041.82249175553 332434.5029388141 322458.35339717666 340499.9841975027 302456.8639589697 305790.282756004 307867.5132377142 321939.9221597363 1.0313558695175797 1.0167497119835327 1.0500152333516128 1.032597947805525 1.0016103353506534 1.0576507005196998 0.9394823168556906 0.9498364809949872 0.9562887111743793 1.0 18.296431963742805 -7.265928570413609 24.99996279898818 0.9572215817116396 1.0304960287985412 0.7302851782760609 0.02084937377374472 189.0443558130755 1052767.337253504 0.008137682201210326 0.005703089000711371 5.4209004208322394e-08 7.265928570413609 0.07327444708690156 STLS(ph)PPEASPGPPAAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STLSPPEASPGPPAAPR 17 0 Q6NUJ5-2;Q6NUJ5 Q6NUJ5-2 PWWP2B PWWP domain-containing protein 2B 1 S(0.203)T(0.203)LS(0.551)PPEAS(0.043)PGPPAAPR 63.062 0.026743 3209500.0 11312.0 11117.0 12804.0 10981.0 12244.0 10383.0 11166.0 12231.0 10424.0 11142.0 True False 13226.89817781587 12220.622290306535 13109.295919440407 10365.770170882342 9844.876094289433 9838.497201773138 10108.275645160635 11909.949209815708 10576.431279729475 13161.956399976536 1.0049340520410364 0.9284806847049213 0.9959990385216423 0.7875554253394139 0.7479796920089314 0.7474950457813914 0.7679918803847926 0.904876816780592 0.803560728992259 1.0 13.684086327495375 -5.761784288507389 24.999995210970273 0.810280081022425 0.9716722248698476 0.45221401596534105 0.0766022254362608 7.715214720247511 559302.4328848283 0.02090298867013509 0.03331265904046897 1.7306757621506975e-06 5.761784288507389 0.16139214384742262 STLS(ph)PPEASPGPPAAPR ddPTM_PC-9_Lapatinib_30min_R1 1 STLSPPEASPGPPAAPR 17 0 Q6NUJ5-2;Q6NUJ5 Q6NUJ5-2 PWWP2B PWWP domain-containing protein 2B 1 ST(0.005)LS(0.994)PPEASPGPPAAPR 133.23 1.3139e-05 0.0 17353.0 20663.0 17759.0 20705.0 25644.0 21973.0 21314.0 23008.0 21354.0 14996.0 True False 17105.543037849548 20615.156093030928 16298.92357172244 22227.714769855236 24135.670338043816 21033.266011564752 22417.534629797054 24077.0356748335 18948.887652411173 17588.03861908603 0.9725668341032131 1.1721122826430435 0.9267050138288485 1.2637972460291487 1.3722775382044299 1.1958846843069848 1.2745898002219642 1.368943757532224 1.0773735527194255 1.0 14.102306985026084 -5.778286841889379 24.99979477896688 1.2445956862668128 1.038626464316494 0.3308656101212851 0.1256603714337645 238.69910203057574 354202.788292865 0.0334544850312737 0.049768355994752954 1.6661463962548883e-06 5.778286841889379 -0.20596922195031886 STLS(ph)QTVPSK ddPTM_PC-9_AZD4547_30min_R2 2 STLSQTVPSK 10 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 S(0.019)T(0.069)LS(0.908)QT(0.004)VPSK;STLS(0.991)QT(0.008)VPSK 94.402 0.0063163 18462300.0 73793.0 89190.0 81762.0 94452.0 104593.0 106412.0 105451.0 158753.0 116932.0 107333.0 True False 97257.63901024881 118018.9232944889 80677.78245765816 72677.55066885328 90072.06735659808 99758.04081807412 114835.93471434458 134221.37163102278 123112.78679859062 103575.3043396226 0.939004134531353 1.1394504128851584 0.7789287511346947 0.7016880243049459 0.8696287974327596 0.9631450417077058 1.1087192593496848 1.2958819912410005 1.1886307028836214 1.0 16.660320533890975 -7.2409722292825975 2.6284119589884716 1.1835290841338941 0.8860371808031019 0.4869745515014908 0.12698380520224567 0.24893961327074793 3.407044891905444 0.06253697619265315 0.04257297219333746 5.7415317493672295e-08 7.2409722292825975 -0.29749190333079223 STLS(ph)QTVPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STLSQTVPSK 10 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 ST(0.002)LS(0.994)QT(0.004)VPSK;S(0.001)T(0.004)LS(0.936)QT(0.059)VPSK 112.5 0.0014425 16071100.0 111714.0 133482.0 82075.0 72287.0 88333.0 58528.0 68940.0 76195.0 61836.0 50523.0 True False 130624.97374792444 146733.21080819448 84031.9792711709 68236.99374761617 71024.78275374629 55458.6886473445 62409.5041176226 74194.96198527576 62740.23451778128 59682.41996015203 2.188667514406058 2.4585667086918286 1.4079854558055163 1.1433349015200078 1.1900452897380362 0.9292298918906509 1.0456932570644983 1.243162761074589 1.0512347615875974 1.0 15.865018413697038 -5.388629797842062 3.2668776353814257 1.0978325292798814 2.3325382499166207 0.9479393656186909 0.11395324398625337 0.048580337481840964 0.9573354632396334 0.03159057313367974 0.07534601639785476 4.086675951378196e-06 5.388629797842062 1.2347057206367393 up STLS(ph)QTVPSKGELSR ddPTM_PC-9_AZD4547_30min_R2 1 STLSQTVPSKGELSR 15 1 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 S(0.073)T(0.199)LS(0.707)QT(0.021)VPSKGELSR 71.402 0.010263 4863200.0 16268.0 10852.0 17627.0 29232.0 23762.0 11971.0 16795.0 23934.0 17065.0 18551.0 True False 21440.885604579365 14359.69677757366 17393.25446272281 22493.014029897913 20463.056461976215 11222.451477588675 18289.722463773855 20235.550248605723 17967.02106111202 17901.535136484945 1.1977121202796126 0.8021489033254641 0.9716068666800417 1.2564852041127534 1.1430894784140975 0.6268988325317589 1.0216845831560974 1.1303807240175645 1.0036581178165893 1.0 14.12779568987862 -10.34878195490771 0.0028961269008995188 0.06020258458215534 1.940447477455905 0.002729531774363969 0.17853684952639254 1461608.3682098454 862.6485754070563 284533.548730802 275555.44754396734 4.479381428589439e-11 10.34878195490771 1.8802448928737496 STLSAPT(ph)SPCSQSAPSFKPNQVR ddPTM_PC-9_AZD4547_30min_R2 1 STLSAPTSPCSQSAPSFKPNQVR 23 1 K7ER94;Q2V2M9-2;Q2V2M9;Q2V2M9-3;Q2V2M9-4 K7ER94 FHOD3 FH1/FH2 domain-containing protein 3 1 STLS(0.002)APT(0.498)S(0.498)PCS(0.002)QSAPSFKPNQVR 79.461 0.00016013 7938300.0 33242.0 30087.0 38706.0 53515.0 57595.0 46646.0 35034.0 53285.0 38512.0 48888.0 True False 43812.26452344648 39812.03436664748 38192.73314994888 41177.94354850801 49598.92841206633 43729.21824606141 38151.958130149025 45051.027617487925 40547.66569619372 47176.446000349104 0.9286893828993026 0.8438964301455195 0.8095720722511877 0.8728496323822972 1.0513494045672558 0.9269290494188099 0.8087077634009714 0.954947467156694 0.8594896210683964 1.0 15.52577911794881 -6.020753051907075 24.94718897057063 0.9281387822933926 0.8560659632308137 0.1954204975245769 0.06901121446434591 1276.3986865068027 1534355.6524977847 0.02074725590255108 0.027104612853656247 9.533380960851034e-07 6.020753051907075 -0.0720728190625789 STLSAPT(ph)SPCSQSAPSFKPNQVR ddPTM_PC-9_Lapatinib_30min_R1 2 STLSAPTSPCSQSAPSFKPNQVR 23 1 K7ER94;Q2V2M9-2;Q2V2M9;Q2V2M9-3;Q2V2M9-4 K7ER94 FHOD3 FH1/FH2 domain-containing protein 3 1 STLS(0.01)APT(0.445)S(0.445)PCS(0.1)QSAPSFKPNQVR;STLS(0.017)APT(0.486)S(0.486)PCS(0.01)QSAPSFKPNQVR 92.897 0.0011154000000000001 5447300.0 24461.0 20348.9 24389.0 22322.1 29867.0 27360.0 25590.0 25705.0 31972.0 24737.0 True False 24112.181654401982 20301.783372282694 22383.83056426254 23963.741698342692 28110.28178078127 26189.876579275107 26914.92498716836 26899.348140716073 28370.976679914307 29012.75749001939 0.8310889326082416 0.6997536645479722 0.7715168257261568 0.8259725641930589 0.9688938319789638 0.9027020816027096 0.9276927571061558 0.9271558606578383 0.9778793584054924 1.0 14.824399801183855 -6.065357675446807 2.870753030141089 0.9437948203829782 0.7613718659591451 0.8101478414295158 0.040491074426473886 0.10889246230314209 1.7673942674598375 0.012131825634037254 0.017241082019080582 8.602849484590339e-07 6.065357675446807 -0.18242295442383316 STLT(ph)PTQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STLTPTQR 8 0 O75376-2;O75376;A0A088AWL3;E7EVK1 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 S(0.002)T(0.007)LT(0.991)PTQR 86.882 0.029689999999999998 3268800.0 31990.0 31949.0 30065.0 34643.0 34432.0 32265.0 30912.0 26033.0 26518.0 20831.0 True False 37405.27516869956 35120.68557641482 30781.86362214744 32702.065024121377 27685.296772180125 30572.9666007137 27983.791576500607 25349.66133424352 26905.775582872808 24607.49540189472 1.5200764871755068 1.4272352794470342 1.250914126749255 1.3289473182875569 1.1250757673634848 1.242424964482962 1.1372060065221397 1.0301601573109165 1.0933975662066415 1.0 14.586810204547977 -1.5228787452803376 0.2175593589499329 0.9845109817124411 3.8617503113113982 0.8916161705594982 0.053334642293147314 14.826211069278521 0.1883701029989847 0.08305120839305251 14.923532105743849 0.029999999999999995 1.5228787452803376 2.8772393295989573 STLTDSLVCK ddPTM_PC-9_Lapatinib_30min_R1 1 STLTDSLVCK 10 0 P13639 P13639 EEF2 Elongation factor 2 0 112.75 0.0064803 17126000.0 91469.0 101920.0 79783.0 93308.0 86645.0 92780.0 85199.0 79874.0 93183.0 94588.0 False True 90164.63528663975 101684.01050194608 73223.549711286 100170.18158636322 81548.71145062425 88812.01568074351 89610.18733809139 83585.23763437298 82687.74927950886 110937.40976941267 0.8127523030693625 0.9165890091836458 0.6600438018472194 0.9029432163106249 0.7350875743369719 0.8005596657190972 0.8077544583414137 0.7534450083890354 0.745354965934199 1.0 16.759386420530575 -11.067513482561214 3.2445197988546086 1.0068769311735652 0.7935297865146677 0.42225102228279765 0.07273083231662078 39486903.01326669 52303933.52147202 2400525.685173397 0.01713652047485458 8.560251362259707e-12 11.067513482561214 -0.2133471446588976 STLTPT(ph)QR ddPTM_PC-9_AZD4547_30min_R2 1 STLTPTQR 8 0 O75376-2;O75376;A0A088AWL3;E7EVK1 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 STLT(0.076)PT(0.924)QR 108.43 0.004392899999999999 0.0 31601.0 28275.0 30683.0 56491.0 53161.0 41034.0 33743.0 52566.0 40903.0 39292.0 True False 41649.4606583669 37414.34080223877 30276.123372083945 43467.8727272497 45780.51277565519 38468.13749322312 36746.06163114744 44443.1325465116 43065.0490748705 37916.39903955403 1.0984550672894484 0.986758810170989 0.7984968018851204 1.1464135262925264 1.2074066613735495 1.0145514465414693 0.9691337405963655 1.1721348459316758 1.1357895308028974 1.0 15.210534336020286 -5.80754196902356 24.99999790308624 1.0958131995375278 0.9637869030255669 0.2637255981596456 0.1001260064579009 167.81650108487733 91000.84204062345 0.0294053657968911 0.04361537846113133 1.5576075046555694e-06 5.80754196902356 -0.13202629651196085 STLTTLPFPGAEANS(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STLTTLPFPGAEANSPGK 18 0 Q96GV9 Q96GV9 C5orf30 UNC119-binding protein C5orf30 1 STLTTLPFPGAEANS(1)PGK 200.94 3.0233e-54 0.0 13535.0 26095.0 16773.0 18609.0 20035.0 12368.0 15814.0 12910.0 12799.0 12348.0 True False 15826.208171564505 28685.539144152997 17172.931931956737 17566.398061192 16109.285572450894 11719.400307380358 14315.98343655475 12571.126179275678 12986.161161670914 14586.594653285787 1.0849830647758134 1.9665686080946434 1.177309189714705 1.2042836918920607 1.1043897465692656 0.8034363459013676 0.9814479511384737 0.8618273475121142 0.8902805260819147 1.0 13.832355494453923 -5.954392175193438 1.2939091315766067 0.9097520570653485 1.5121907137501331 0.491893209023892 0.22316897719878037 0.3403979793404094 1.1564602701161815 0.07667960213303708 0.15078901439144024 1.1107282680440625e-06 5.954392175193438 0.6024386566847847 STLTTLPFPGAEANS(ph)PGKAEAEKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STLTTLPFPGAEANSPGKAEAEKPR 25 2 Q96GV9 Q96GV9 C5orf30 UNC119-binding protein C5orf30 1 STLTTLPFPGAEANS(1)PGKAEAEKPR;STLTTLPFPGAEANS(1)PGKAEAEKPR 88.555 2.3998e-06 32788000.0 224966.0 212349.0 198138.0 277690.0 261130.0 235086.0 268530.0 260610.0 223788.0 199796.0 True False 263048.30051896395 233429.60535434974 202862.36136254977 262131.92958312717 209963.45103738926 222757.67631474888 243092.89441115767 253769.26363912015 227060.47613469846 236017.43321573435 1.114529113103784 0.9890354376533738 0.8595227843916139 1.1106464722185272 0.8896099248968182 0.943818739487497 1.0299785532747316 1.0752140644083674 0.9620495954091295 1.0 17.84853390133322 -7.292532640374983 24.121379029203677 1.0230784023937969 0.9804682643774527 0.03278521098416087 0.08138868303121241 1503.9573981330848 1166724.8330783285 0.0337709788087191 0.022771590715588624 5.098792750152947e-08 7.292532640374983 -0.04261013801634417 STMGSS(ph)FSYPDVK ddPTM_PC-9_AZD4547_30min_R2 1 STMGSSFSYPDVK 13 0 Q8NAX2 Q8NAX2 KDF1 Keratinocyte differentiation factor 1 1 ST(0.001)MGS(0.214)S(0.782)FS(0.003)YPDVK 96.06700000000001 0.0029561 6590100.0 40832.0 85549.0 67008.0 68029.0 75564.0 47363.0 69092.0 83662.0 62193.0 65353.0 True False 53815.726641639085 113201.04124812465 66119.43013775053 52345.96508757269 65073.24292958385 44401.38412271595 75241.05415106067 70733.96026150479 65480.395010474036 63065.01136190508 0.8533373019281956 1.7949896274260346 1.0484328585674447 0.830031803010071 1.031843831061162 0.7040573396223465 1.193071285110568 1.121603861380293 1.038299900315692 1.0 15.944552195617414 -5.4950513178042915 24.98954722791802 0.9879139991498129 1.3485504823283139 0.22098673625166987 0.24791581780209593 888.6123391893444 797989.0137720169 0.061152715273917295 0.12680630561140227 3.1985171390251225e-06 5.4950513178042915 0.36063648317850094 STMGSS(ph)FSYPDVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STMGSSFSYPDVK 13 0 Q8NAX2 Q8NAX2 KDF1 Keratinocyte differentiation factor 1 1 STMGS(0.014)S(0.973)FS(0.014)YPDVK;S(0.003)T(0.061)MGS(0.061)S(0.869)FS(0.006)YPDVK 135.58 4.5422e-05 12465500.0 141997.0 100903.0 91110.0 73483.0 213860.0 60107.0 69684.0 83856.0 63500.0 65811.0 True False 166034.28753141063 110919.98299530432 93282.40793659906 69365.98574510051 171955.6682068554 56954.883107673864 63083.027051529156 81654.86885277639 64428.56736980252 77742.01334041054 2.135708613621735 1.4267701366263403 1.1998969917095081 0.8922586741015601 2.2118756746613903 0.7326139452844417 0.8114406141670941 1.0503312860606342 0.8287483768613997 1.0 16.246406850213617 -6.8107843909271715 24.999989395446644 0.8831976817832916 1.5065861387176327 0.44629324761787803 0.3799242971930009 118.38418432722186 59976.87925710888 0.13507922564986535 0.11912888588317228 1.5460217842947496e-07 6.8107843909271715 0.6233884569343411 STMGSS(ph)FSYPDVK ddPTM_PC-9_Lapatinib_30min_R1 1 STMGSSFSYPDVK 13 0 Q8NAX2 Q8NAX2 KDF1 Keratinocyte differentiation factor 1 1 S(0.002)T(0.002)MGS(0.389)S(0.548)FS(0.06)YPDVK 93.958 0.003889 2796100.0 27884.0 29763.0 12618.0 8906.4 13415.0 9349.1 6314.8 6578.3 15078.0 6361.4 True False 27486.36904670065 29694.08560213328 11580.596746888543 9561.406366879428 12625.956074904763 8949.26078681655 6641.749445446301 6883.951833264833 13379.756861621036 7460.959513967314 3.6840260284544772 3.9799285261559683 1.5521591727188773 1.2815250302564927 1.692269747780872 1.1994785349073478 0.8902004404410173 0.9226630730776261 1.7933024347033941 1.0 12.865145464341754 -5.299297512688512 4.770260946582367 1.2675634832403686 3.8533644841834147 0.9219221666091602 0.2962635404873701 0.04513680292049669 2.540889971316573 0.08078923684559937 0.18573946367596988 5.019985784402417e-06 5.299297512688512 2.585801000943046 STNGDTFLGGEDFDQALLR ddPTM_PC-9_AZD4547_30min_R2 2 STNGDTFLGGEDFDQALLR 19 0 P38646 P38646 HSPA9 Stress-70 protein, mitochondrial 0 ; 184.99 3.599e-10 7041900.0 16844.0 18410.4 21081.1 27376.4 24266.0 18008.9 17050.4 24951.0 18888.1 21397.1 False True 22200.041623035086 24361.201765005735 20801.550839853964 21065.193941163696 20897.084761649498 16882.800636099466 18567.85256899848 21095.396266940825 19886.486405179607 20647.994041770373 1.075166990949579 1.1798338238437902 1.0074368869815127 1.0202053477228508 1.0120636764702287 0.8176484651218896 0.8992569705045528 1.0216680721752132 0.9631195342729054 1.0 14.333714009786842 -5.70129978880299 1.323761512942306 0.9446244404340683 1.1283505356698724 0.49842704157925477 0.06484316214095832 0.39748588132333756 1.3646702425242385 0.0230339852146795 0.06218524409570589 1.9892996727912387e-06 5.70129978880299 0.18372609523580408 STNGDTFLGGEDFDQALLR ddPTM_PC-9_Lapatinib_30min_R1 2 STNGDTFLGGEDFDQALLR 19 0 P38646 P38646 HSPA9 Stress-70 protein, mitochondrial 0 ; 120.32 0.00020708 11258900.0 19600.8 16458.6 19257.199999999997 16275.3 16055.0 14234.7 15181.0 15423.599999999999 19310.3 11340.0 False True 19321.2889976535 16420.491122913376 17673.947350941682 17472.239854809228 15110.676465344466 13625.915063706398 15966.997898796513 16140.236762620047 17135.37066752626 13300.103890399809 1.4527171484427173 1.2346137487516848 1.3288578417570838 1.3136919830694647 1.1361322129409495 1.0244968893469895 1.2005167801976122 1.2135421569353517 1.2883636705946933 1.0 13.699149894567585 -6.2420584331977915 7.60917644998469 1.1513199737461344 1.325647039695138 0.4885612844519548 0.09426532753238985 0.19196640701607584 57.958870948028895 0.028559150829393483 0.03593333484838637 5.727189679477364e-07 6.2420584331977915 0.1743270659490037 STNNVERHT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STNNVERHTPR 11 1 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 STNNVERHT(1)PR 84.17299999999999 0.0087599 2172800.0 10436.0 7260.7 11311.0 13207.0 13606.0 12611.0 12767.0 11078.0 9498.8 8528.6 True False 12202.608679604522 7981.494311705375 11580.69713720638 12467.054607671718 10940.001971488235 11949.656959603306 11557.617334924402 10787.21423811123 9637.701980035916 10074.767667639542 1.2112049708897674 0.7922261410893053 1.1494753545934293 1.2374533109796937 1.0858813158171232 1.1860975214332699 1.147184502531787 1.070715930528114 0.9566177899062135 1.0 13.298458948961843 -8.10818468220415 4.14827024320041 0.9802972685293114 1.1107543171159069 0.17458714527934138 0.11741591130825269 0.445082610205003 12.681012933723812 0.08914801589603255 0.031240282224775654 7.794985610059228e-09 8.10818468220415 0.13045704858659546 STNT(ph)SQTGLVGTK ddPTM_PC-9_AZD4547_30min_R2 2 STNTSQTGLVGTK 13 0 Q96R06 Q96R06 SPAG5 Sperm-associated antigen 5 1 STNT(0.956)S(0.044)QTGLVGTK;S(0.044)T(0.001)NT(0.912)S(0.043)QTGLVGTK 164.15 3.3761e-12 11775000.0 68503.0 72610.0 91538.0 124974.0 88816.0 103816.0 70946.0 90685.0 87139.0 99149.0 True False 90285.52904908404 96079.76253406036 90324.14631013332 96163.17512905254 76485.43147575442 97324.36910845767 77260.05655938659 76671.71698398955 91744.98964220565 95677.82368860685 0.9436411235996277 1.0042009614136047 0.9440447412777948 1.0050727683985092 0.7994060538488417 1.0172092691532122 0.8075022359500699 0.8013530620588257 0.958895030271581 1.0 16.54589695356119 -6.232074741140826 24.995293298969955 0.8889580523016376 0.9742231815057933 0.18716465236080448 0.07726285549046275 1090.471206130982 928213.1499688113 0.022014540907212953 0.028416530193769222 5.860373000834331e-07 6.232074741140826 0.08526512920415574 STNT(ph)SQTGLVGTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STNTSQTGLVGTK 13 0 Q96R06 Q96R06 SPAG5 Sperm-associated antigen 5 1 S(0.001)T(0.037)NT(0.721)S(0.241)QTGLVGTK 98.676 0.006442399999999999 0.0 42207.0 35368.0 57697.0 48365.0 56707.0 49482.0 47931.0 43603.0 43148.0 38253.0 True False 49351.81147375124 38879.10130103096 59072.71529709097 45655.26585144564 45595.67042460559 46887.07681191743 43390.62868961085 42458.467451197306 43778.95787200379 45187.96608941864 1.0921450055108282 0.8603861750293519 1.3072665226887392 1.01034124353157 1.0090224095145195 1.0376009559522235 0.9602253087414647 0.9395967804167119 0.9688189502792252 1.0 15.46365100230864 -6.8774118413627106 1.3791560176621571 0.962467148480963 1.0644619946505551 0.1430891224805726 0.10422312614199072 0.8493725598214574 3.3493339142959893 0.05144249107392726 0.04196675371628929 1.3261362865102748e-07 6.8774118413627106 0.10199484616959209 STNT(ph)SQTGLVGTK ddPTM_PC-9_Lapatinib_30min_R1 2 STNTSQTGLVGTK 13 0 Q96R06 Q96R06 SPAG5 Sperm-associated antigen 5 1 STNT(0.99)S(0.01)QTGLVGTK;ST(0.003)NT(0.99)S(0.007)QTGLVGTK 184.51 2.027e-27 0.0 54779.0 47790.0 65413.0 54339.0 47548.0 37440.0 43660.0 36433.0 56035.0 36828.0 True False 53997.84141476172 47679.34519120886 60034.99564148206 58335.271329590134 44751.32012296474 35838.77847690275 45920.50116997932 38125.81018520555 49723.748225290845 43193.67072977462 1.2501331908690845 1.103850272172912 1.3899026090435571 1.3505513734765306 1.036061982389387 0.8297229170707658 1.06313032428441 0.8826712233772794 1.151181350998605 1.0 15.398532305925634 -6.37261896503434 5.265331360406707 0.9784682329871508 1.2686370229570674 0.6143739905279257 0.10887594590266204 0.15300987819670622 6.134297089628748 0.034171921657572 0.03883432018489345 4.240148188449355e-07 6.37261896503434 0.2901687899699166 STPENHPET(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 STPENHPETPK 11 0 A0A590UJS4;Q6KC79-2;Q6KC79;Q6KC79-3 A0A590UJS4 NIPBL Nipped-B-like protein 1 STPENHPET(1)PK 101.72 0.0075819 30766000.0 49348.0 49099.0 60248.0 71043.0 59321.0 79259.0 78326.0 60221.0 72936.0 80168.0 True False 65039.63749783515 64969.29156672405 59449.07215465609 54665.133953408505 51085.30310499502 74302.92220050114 85296.8622624323 50915.228190911876 76791.24805820482 77361.34272123998 0.8407252926335024 0.8398159763181874 0.768459673313478 0.7066208009132692 0.6603466448232842 0.9604657776977915 1.1025773243076555 0.6581481965014139 0.9926307553232443 1.0 16.23932521470111 -6.778315952419702 24.99248619090269 0.931387016559951 0.764600079661678 0.36522629522759276 0.11788446844726222 304.9860813032942 451650.38707106764 0.04249606595553538 0.03757424763407834 1.666034719082594e-07 6.778315952419702 -0.16678693689827306 STPFIVPS(ph)SPTEQEGR ddPTM_PC-9_AZD4547_30min_R2 6 STPFIVPSSPTEQEGR 16 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 STPFIVPS(0.486)S(0.486)PT(0.027)EQEGR;STPFIVPS(0.444)S(0.444)PT(0.112)EQEGR;STPFIVPS(0.499)S(0.499)PT(0.003)EQEGR;STPFIVPS(0.559)S(0.394)PT(0.046)EQEGR;STPFIVPS(0.745)S(0.255)PTEQEGR;STPFIVPS(0.447)S(0.447)PT(0.105)EQEGR 243.99 7.306499999999999e-47 879454000.0 933915.7 925834.0 1406344.0 1797927.0 1402377.0 1386368.0 1101327.6 1457758.0 1201433.0 1360142.0 True False 1230881.4659466813 1225091.7348293525 1387694.9596711544 1383442.7078452483 1207681.1603390616 1299678.1897988168 1199343.6228457373 1232494.997046332 1264938.2956059186 1312523.8425750036 0.9377974144316111 0.933386270854996 1.0572721916797143 1.0540324396173337 0.9201213122115526 0.990213013768203 0.9137690180871524 0.9390267491281034 0.9637450037663863 1.0 20.323912199533254 -6.286471734387186 24.9848511004931 0.9511817066306275 0.9955802638615429 0.15987022663946726 0.04583253270399628 1450.5730425582885 1447816.0377756006 0.015127811118050848 0.017160598920741007 5.170449082133951e-07 6.286471734387186 0.04439855723091535 STPFIVPS(ph)SPTEQEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STPFIVPSSPTEQEGR 16 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 STPFIVPS(0.68)S(0.313)PT(0.006)EQEGR;STPFIVPS(0.455)S(0.455)PT(0.091)EQEGR;STPFIVPS(0.755)S(0.245)PTEQEGR;STPFIVPS(0.5)S(0.5)PTEQEGR 225.6 1.1891e-28 239880000.0 345242.0 330720.0 376125.0 394057.0 458661.0 370140.0 404823.0 322874.0 324129.0 303933.0 True False 403684.6517596796 363551.69594766333 385093.24646200653 371979.26384003164 368789.66957553866 350729.20680576994 366475.2347752877 314398.899613281 328868.7734331765 359033.6469676949 1.1243644019692736 1.012583915235039 1.0725826108901053 1.036056834733101 1.027173003673167 0.976870022539497 1.020726714252111 0.875680879128217 0.9159831570403412 1.0 18.45375952750682 -6.913361166073045 0.9155552773914444 0.930652126266072 1.0649564970784626 0.5625861536233453 0.04486894001442088 0.4071581080065949 0.7211850034691139 0.028794480999761153 0.022791610805311637 1.2207840148597725e-07 6.913361166073045 0.13430437081239066 STPFIVPS(ph)SPTEQEGR ddPTM_PC-9_Lapatinib_30min_R1 5 STPFIVPSSPTEQEGR 16 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 STPFIVPS(0.703)S(0.294)PT(0.003)EQEGR;STPFIVPS(0.755)S(0.244)PT(0.001)EQEGR;STPFIVPS(0.494)S(0.494)PT(0.013)EQEGR;STPFIVPS(0.492)S(0.492)PT(0.015)EQEGR;STPFIVPS(0.456)S(0.456)PT(0.087)EQEGR 251.28 1.1251999999999999e-47 796614500.0 1037479.0 1270860.0 1469952.0 1231851.0 1447054.0 1469925.0 1347952.0 1417006.0 1437215.0 1129285.0 True False 1022684.359209653 1267917.401751403 1349098.2207388117 1322445.4318744717 1361941.1287376261 1407059.7343125362 1417742.3589802112 1482845.2717947282 1275340.712155105 1324480.4075723237 0.7721400432673512 0.9572941921242938 1.0185867703483893 0.9984635667796838 1.0282833335632084 1.0623484698362389 1.0704139909316062 1.1195675400836438 0.9628988883970824 1.0 20.33699507206734 -4.067645091270771 1.0097178289715014 1.0446671768576197 6.987214618559035e-11 0.7836312225158627 0.04144839580088179 2.932095190013111 0.8564755026235908 0.01314338736033167 4.693508270285095 8.55765765454219e-05 4.067645091270771 -1.0446671767877476 STPFIVPSS(ph)PTEQEGR ddPTM_PC-9_AZD4547_30min_R2 1 STPFIVPSSPTEQEGR 16 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 STPFIVPS(0.025)S(0.882)PT(0.093)EQEGR 193.54 1.0414e-11 86228000.0 47112.0 40098.0 47373.0 63213.0 54784.0 53926.0 39868.0 60223.0 48157.0 39263.0 True False 62092.63600952441 53058.8943408725 46744.803067031666 48640.21948111445 47178.18724067441 50553.99869521736 43416.17476545015 50916.91913686731 50702.48070553596 37888.4143207271 1.6388291017910517 1.4003989159252384 1.2337492583177234 1.2837755380674643 1.2451876935600676 1.3342864725685146 1.1458957980645565 1.3438651379245736 1.338205401691853 1.0 15.209469142001154 -4.824476413435094 2.0937699651364863 1.253846772627896 1.7260723995285312 0.601268424411488 0.09998521724079251 0.4131732258154814 2.2155672927006473 0.024960284152135966 0.3633447337045752 1.4980406095301013e-05 4.824476413435094 0.4722256269006353 STPFIVPSS(ph)PTEQEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STPFIVPSSPTEQEGR 16 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 STPFIVPS(0.416)S(0.563)PT(0.021)EQEGR;STPFIVPS(0.225)S(0.774)PT(0.001)EQEGR;STPFIVPS(0.199)S(0.772)PT(0.029)EQEGR;STPFIVPS(0.491)S(0.495)PT(0.014)EQEGR 273.44 3.3762e-82 275643500.0 257489.7 246880.0 282005.0 292695.0 310996.0 260001.0 281804.0 238930.7 249523.0 216692.8 True False 301077.6205566087 271388.61482692 288729.06870991876 276296.24807999376 250058.56630346586 246366.0898543985 255109.48503571944 232659.02229300266 253171.8018238622 255977.48930073922 1.1761878803447552 1.0602050030581975 1.1279471077657959 1.079377131304631 0.976877173795859 0.9624521692411452 0.9966090601662242 0.9089042279794358 0.9890393194942985 1.0 17.965657419419415 -6.190637991313545 2.8382151098345987 0.9667681250594641 1.1150232731458938 0.7857940258653446 0.035852115220454395 0.11754359381513964 1.8601613761810631 0.01082342648326801 0.014257946984958369 6.447064403973458e-07 6.190637991313545 0.1482551480864297 STPFIVPSS(ph)PTEQEGR ddPTM_PC-9_Lapatinib_30min_R1 2 STPFIVPSSPTEQEGR 16 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 STPFIVPS(0.227)S(0.773)PTEQEGR;STPFIVPS(0.219)S(0.74)PT(0.041)EQEGR 227.41 8.8874e-29 33923000.0 33867.0 40713.0 52855.0 39373.0 43362.0 42394.0 42644.0 42043.0 49783.0 37219.0 True False 33384.050369552846 40618.731549899254 48509.46592620018 42268.62176447768 40811.532412972054 40580.90744524079 44851.897661305484 43996.47126551743 44175.91430176948 43652.254558799876 0.7647726493618859 0.9305070714087758 1.1112705727686438 0.968303291357874 0.9349238160883225 0.9296405845562464 1.0274818131304004 1.0078854279165328 1.0119961671685074 1.0 15.413768547878439 -4.830036301378541 3.6942479313178325 0.9957193535218025 0.7514587377918246 0.6735341726859319 0.04911242978125611 0.14693095102927128 3.3986992782814736 0.01303200090795102 0.08973524567659516 1.47898475908298e-05 4.830036301378541 -0.24426061572997793 STPFIVPSSPT(ph)EQEGR ddPTM_PC-9_AZD4547_30min_R2 1 STPFIVPSSPTEQEGR 16 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 STPFIVPS(0.301)S(0.301)PT(0.397)EQEGR 86.772 0.015203 0.0 8261.0 7383.3 7888.5 11693.0 10030.0 9835.3 8207.5 11011.0 7636.7 11163.0 True False 10887.826160525578 9769.80733669919 7783.893335745666 8997.359505049135 8637.50763040239 9220.297136206485 8937.951599965696 9309.502957608325 8040.3603713679495 10772.186767752764 1.0107349970127688 0.9069474515560516 0.722591754447412 0.8352398356091737 0.801834188046138 0.8559355064106425 0.8297249010499921 0.8642166310629632 0.7464000155880407 1.0 13.395023528108695 -4.952550087342585 4.272685613119778 0.826052586116245 1.0007361552040552 0.374135105444415 0.07128336189330031 0.19480384798372324 7.488386412257554 0.016612780005371534 0.07573036691101775 1.1154494987306152e-05 4.952550087342585 0.17468356908781024 STPFIVPSSPT(ph)EQEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STPFIVPSSPTEQEGR 16 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 STPFIVPS(0.062)S(0.212)PT(0.726)EQEGR 236.75 1.0993e-36 226700000.0 86200.0 84797.0 98826.0 95249.0 112540.0 86611.0 103740.0 78265.0 85064.0 79706.0 True False 100791.9574723947 93215.08575615025 101182.38663969224 89912.50733142465 90488.59487514947 82068.96669004849 93912.9961874408 76210.62667862202 86307.9000747226 94156.06684765127 1.0704775682217123 0.9900061554926294 1.0746241854325742 0.9549305779404222 0.9610490104855811 0.8716269640153911 0.9974184280594074 0.8094075000173301 0.9166472534836512 1.0 16.522766435929384 -6.067189535704626 1.7647566774157004 0.9135986684193221 1.0405510516271566 0.4359488553272971 0.05886172575754375 0.31440320878774447 1.9550240268610506 0.018952424143796835 0.029448876565929386 8.566638965900638e-07 6.067189535704626 0.12695238320783442 STPFIVPSSPT(ph)EQEGRQDKPMDTSVLSEEGGEPFQK ddPTM_PC-9_AZD4547_30min_R2 2 STPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQK 36 2 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 S(0.001)T(0.001)PFIVPS(0.181)S(0.181)PT(0.633)EQEGRQDKPMDT(0.002)S(0.001)VLSEEGGEPFQK;STPFIVPS(0.119)S(0.119)PT(0.634)EQEGRQDKPMDT(0.102)S(0.024)VLS(0.002)EEGGEPFQK 62.302 5.8188999999999995e-05 10215900.0 24145.1 12180.7 25924.6 74669.0 47605.0 29639.0 19182.3 25578.9 17936.1 30488.0 True False 31822.73955072101 16117.873068428995 25580.82286516727 57455.21567455012 40995.8674721142 27785.668644578633 20889.487538960933 21626.268749647406 18884.16562872613 29420.62439982496 1.081647320541244 0.5478426579051425 0.8694860624820547 1.952889064954446 1.393439748762032 0.9444282441790715 0.7100286946692137 0.7350717121345689 0.6418682816547728 1.0 14.844540245073933 -6.995091382894068 6.047863609693956 0.75857588788516 1.1633260377337185 0.2232628542408922 0.3497697211264822 0.2690255565858325 39.887037751515 0.14426999036909832 0.12149637506628409 1.0113666232499188e-07 6.995091382894068 0.4047501498485585 STPFIVPSSPT(ph)EQEGRQDKPMDTSVLSEEGGEPFQK ddPTM_PC-9_Lapatinib_30min_R1 1 STPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQK 36 2 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 S(0.002)T(0.002)PFIVPS(0.157)S(0.157)PT(0.564)EQEGRQDKPMDT(0.053)S(0.053)VLS(0.012)EEGGEPFQK 42.24100000000001 0.015386000000000002 4100400.0 26938.0 6530.8 8450.3 6899.8 6376.4 6833.8 6069.4 4477.6 9809.5 3595.6 True False 26553.859180175812 6515.678333851154 7755.548953101302 7407.234309058059 6001.352688484733 6541.53430436587 6383.643834197723 4685.6456422824485 8704.650811385567 4217.094669164158 6.296718775212811 1.5450633303289305 1.839073950559065 1.756478070843545 1.4231012484417904 1.551194558708454 1.513753978746458 1.1111075301544413 2.064134550982432 1.0 12.042033693568824 -4.761401727566316 24.998001570303305 1.550200648049372 6.2967239484703255 0.9576336639876272 0.3005261695535637 0.15241577542807203 99873.75808288703 0.07065583399189714 0.39431732768683425 1.7322009499476195e-05 4.761401727566316 4.746523300420954 STPGSNRSS(ph)PGNK ddPTM_PC-9_Lapatinib_30min_R1 1 STPGSNRSSPGNK 13 1 O15231-4;O15231-5 O15231-4;O15231-5 ZNF185 Zinc finger protein 185 1 STPGS(0.001)NRS(0.173)S(0.826)PGNK 51.611999999999995 0.046035 2336600.0 14436.0 13823.0 15213.0 13593.0 18920.0 13858.0 13848.0 13737.0 17690.0 15095.0 True False 14230.139992761819 13790.99369278259 13962.24586387822 14592.674564918727 17807.16279815119 13265.325644575807 14564.981681215604 14375.271169384047 15697.565916041669 17704.15063717681 0.8037742269815564 0.7789695182452294 0.7886425138384785 0.8242516042693222 1.0058185316587889 0.74927772116444 0.8226874013730268 0.8119718061592589 0.8866602096730059 1.0 14.11180001113898 -14.522878745187796 0.19350842747900535 1.7493635748069847 0.7998111231895059 0.39518040809590327 0.06598661022814825 153.07071423430187 1.4995928077575404 44.20815692196056 0.17802695690211837 3.0000000006392525e-15 14.522878745187796 -0.9495524516174788 STPGSNS(ph)ADGGR ddPTM_PC-9_AZD4547_30min_R2 2 STPGSNSADGGR 12 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;H7C1R1;O15231-3 O15231-7;O15231-3 ZNF185 Zinc finger protein 185 1 STPGS(0.04)NS(0.96)ADGGR;STPGS(0.05)NS(0.95)ADGGR 125.47 0.00029211 4170800.0 8993.400000000001 8340.5 11289.3 13584.7 12706.0 9814.9 8304.3 12198.1 9104.900000000001 13237.900000000001 True False 11853.114125659216 11036.403517632973 11139.596505702415 10452.957296522794 10941.991221524706 9201.17275143139 9043.36661243925 10313.163929452554 9586.166425978243 12774.445150303172 0.9278770221482309 0.863943865097816 0.8720219449561019 0.8182709443372355 0.8565531491021371 0.72027963979422 0.707926372224834 0.8073277397263547 0.7504174399113325 1.0 13.64097300955462 -5.785688471379233 1.1301789025894435 0.785624242638269 0.9043197117961627 0.1629931955602506 0.07974062067800264 0.8169915214228833 2.036962530478644 0.028459083020746487 0.07597017970825726 1.6379910657631398e-06 5.785688471379233 0.11869546915789364 STPGSNS(ph)ADGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STPGSNSADGGR 12 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;H7C1R1;O15231-3 O15231-7;O15231-3 ZNF185 Zinc finger protein 185 1 ST(0.006)PGS(0.031)NS(0.963)ADGGR;STPGS(0.022)NS(0.978)ADGGR 111.66 0.0020109999999999998 0.0 6650.3 10811.2 9521.4 12380.2 12984.3 11235.9 9018.0 10586.4 11232.7 8640.9 True False 7776.064440587769 11884.46448726833 9748.426286110585 11686.577531149951 10440.119623577442 10646.669624328504 8163.749755333924 10308.518217217983 11396.95698731939 10207.426768673236 0.7618045778640942 1.1642958364141245 0.9550326940408398 1.1449092700832548 1.022796426580139 1.0430316930613024 0.7997852877464288 1.0099037152884602 1.1165357582869802 1.0 13.317331596796476 -4.7404031969955405 24.912392623641146 1.0232603371561109 0.7618035668945934 0.39150183656362425 0.09954721373614676 1703.1514048071328 2016872.4444334102 0.02496594751711904 1.1076770576060486 1.8180122406928268e-05 4.7404031969955405 -0.2614567702615175 STPGSNS(ph)ADGGR ddPTM_PC-9_Lapatinib_30min_R1 2 STPGSNSADGGR 12 0 O15231-7;O15231;O15231-8;O15231-6;H7BZT5;H7C1R1;O15231-3 O15231-7;O15231-3 ZNF185 Zinc finger protein 185 1 ST(0.001)PGS(0.045)NS(0.954)ADGGR;STPGS(0.042)NS(0.958)ADGGR 128.35 0.001389 1523600.0 9266.6 9002.5 10565.099999999999 9561.2 9686.9 8291.3 7592.1 8944.8 10893.400000000001 8700.4 True False 9134.456584713684 8981.655264361954 9696.478260465381 10264.362543228195 9117.135587178152 7936.700426964315 7985.181789569399 9360.40806259783 9666.470579412564 10204.252547445725 0.8951617516561928 0.8801874730756438 0.9502389533560254 1.0058906809198402 0.8934643223290574 0.7777836142394366 0.7825347081955756 0.9173046256034576 0.9472982498686024 1.0 13.316882889643125 -1.5452989979273601 23.073187639156636 0.8988058308746842 0.004478206168756049 0.0 0.07456561964540499 0.0 0.0 0.01852113004245852 0.0 0.028490561076933645 1.5452989979273601 -0.8943276247059282 STPKEDDSSASTSQSTR ddPTM_PC-9_AZD4547_30min_R2 2 STPKEDDSSASTSQSTR 17 1 E7EX17;P23588-2;P23588;F8VX11 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 ; 86.539 0.0039511 4024600.0 13702.2 9608.1 19695.9 23808.9 20932.6 15976.8 12718.4 17522.8 13471.5 14481.0 False True 18059.21457653476 12713.730428363946 19434.71949692757 18320.125948838147 18026.46981297716 14977.768170339888 13850.312961194479 14815.053893886032 14183.575987387672 13974.024597673353 1.292341690849863 0.9098116537222037 1.3907746734726236 1.3110128596659556 1.2899984315168969 1.0718292404346887 0.9911470288595691 1.0601851879059028 1.0149957793654671 1.0 13.770459964427523 -6.885859308313944 5.079150585920253 1.0230195163763738 1.232278269949427 0.43724871323383707 0.1206738021804891 0.22528177127997784 9.115107509379438 0.04472610491716236 0.03940158403190885 1.3005908421531334e-07 6.885859308313944 0.20925875357305324 STPKEDDSSASTSQSTR ddPTM_PC-9_Lapatinib_30min_R1 3 STPKEDDSSASTSQSTR 17 1 E7EX17;P23588-2;P23588;F8VX11 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 ;; 98.552 0.001743 5209600.0 27562.5 19282.8 24271.300000000003 23521.800000000003 23177.0 23579.399999999998 21449.9 17672.100000000002 25123.0 18198.6 False True 27169.453695656557 19238.15186133171 22275.8074039274 25251.671638424585 21813.774427735203 22570.964028266044 22560.470866833235 18493.210281172862 22293.38318308167 21344.203761889774 1.2729195241364688 0.9013290950530357 1.0436466804960423 1.183069273519194 1.021999914875431 1.0574751009717522 1.0569834845334036 0.8664277425139943 1.044470125556366 1.0 14.38155672390126 -7.55636893859692 24.23967229393007 0.9656102777433029 1.071075955590514 0.18761079526227065 0.10133204632660492 227.62437824359813 164747.71628369193 0.045655431512244486 0.026359393615766235 2.7773528692903602e-08 7.55636893859692 0.10546567784721117 STPLAS(ph)PSPSPGR ddPTM_PC-9_Lapatinib_30min_R1 2 STPLASPSPSPGR 13 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 S(0.003)T(0.01)PLAS(0.977)PS(0.009)PSPGR;S(0.039)T(0.026)PLAS(0.935)PS(0.001)PSPGR 115.37 0.0002904 5767600.0 33882.0 30057.0 65936.0 29625.0 44377.0 52934.0 45789.0 41969.0 69558.0 27414.0 True False 33398.83646680219 29987.404863196563 60514.99660032037 31803.721326102917 41766.83210853888 50670.13621518085 48159.730372702325 43919.032955367176 61723.64556178777 32152.473373141114 1.0387641435604837 0.9326624585045714 1.8821257045460202 0.9891531813745461 1.2990239234107948 1.5759327634653653 1.497854607133678 1.3659612573400146 1.9197168704709737 1.0 14.972642102667598 -6.625124094935854 5.62133908648562 1.494899611062127 1.2279593124441732 0.12432406225030479 0.32513908218793175 0.44424822419776777 20.781260561586283 0.10611035400339826 0.10591540638392179 2.3706962081544467e-07 6.625124094935854 -0.2669402986179539 STPLASPS(ph)PSPGRSPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STPLASPSPSPGRSPQR 17 1 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 STPLAS(0.008)PS(0.501)PS(0.47)PGRS(0.021)PQR 77.597 0.036568 7007100.0 11649.0 9107.2 13097.0 15991.0 15606.0 15213.0 16094.0 15914.0 18374.0 11098.0 True False 13620.945621762463 10011.302628612006 13409.282150649089 15095.07611352149 12548.116328608374 14415.203499044084 14569.459809530294 15496.274362276787 18642.684989807123 13109.979548280335 1.0389753524481395 0.7636398357253891 1.0228301349568478 1.1514187385213386 0.957142326759338 1.0995595718480704 1.1113258991652204 1.18202124612082 1.4220224311679057 1.0 13.678377814489929 -6.5009462167064775 0.6471796655981628 1.208608610565399 0.9146181402627589 0.32377542676735327 0.1326272809044041 0.9134330312577038 0.8449017573247336 0.09552727840155972 0.13587717903408458 3.155395365265834e-07 6.5009462167064775 -0.29399047030264014 STPLASPS(ph)PSPGRSPQR ddPTM_PC-9_Lapatinib_30min_R1 1 STPLASPSPSPGRSPQR 17 1 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 STPLAS(0.037)PS(0.423)PS(0.296)PGRS(0.243)PQR 108.72 0.0063097000000000006 0.0 11871.0 13400.0 10824.0 8114.0 9847.2 10017.0 10530.0 13178.0 11883.0 9316.9 True False 11701.717363125224 13368.973123293548 9934.092501848274 8710.730627510526 9268.007056340088 9588.596260767497 11075.191876314291 13790.2979886542 10544.611406462576 10927.313751011108 1.0708686169135082 1.223445526313044 0.9091065497162163 0.7971520563967076 0.8481505397868269 0.8774888759719434 1.0135328891137128 1.2620025655782217 0.9649774543617254 1.0 13.41565116807957 -9.41673946785643 11.955385072457604 1.0000141150423905 0.9950310066274172 0.0 0.14573023033761326 0.0 0.0 0.1569304734586879 0.03806123046755054 3.8305446779516243e-10 9.41673946785643 -0.004983108414973292 STPLASPSPSPGRS(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 1 STPLASPSPSPGRSPQR 17 1 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 STPLAS(0.151)PS(0.229)PS(0.229)PGRS(0.39)PQR 136.39 0.00023939 4129100.0 15291.0 13178.0 12771.0 11266.0 11686.0 12876.0 13445.0 11515.0 14600.0 10373.0 True False 15072.94753597402 13147.487150653898 11721.017677485628 12094.539222274283 10998.652455559974 12325.323495422006 14141.116313109746 12050.028937574234 12955.59425518418 12165.959228846315 1.2389444393529643 1.0806782189011708 0.9634273349933887 0.9941295211311665 0.9040513985515768 1.0130991945294232 1.1623511181576376 0.9904709288358289 1.0649052829690229 1.0 13.570562454050387 -4.828640242089577 3.048673211808529 1.0123511759693988 1.262674179560272 0.5381729736962394 0.06376294747240606 0.27068537468942505 3.9343432048683487 0.017392707967864438 0.15693815509512565 1.4837466721926535e-05 4.828640242089577 0.2503230035908732 STPLPGPPGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 STPLPGPPGSPR 12 0 J3KNK0;Q8TDC3;Q8TDC3-2 J3KNK0 BRSK1 Serine/threonine-protein kinase BRSK1 1 STPLPGPPGS(1)PR 91.20200000000001 0.0065327 3163200.0 17795.0 16548.0 26478.0 36114.0 31680.0 32095.0 19880.0 32503.0 20843.0 25709.0 True False 23453.439841006246 21896.817386222723 26126.88441958215 27788.475255737994 27281.778836604954 30088.094576326843 21649.281487336953 27480.408194636566 21944.718428172153 24808.935735210565 0.9453625939995279 0.8826181670963514 1.053123950919872 1.120099449340693 1.0996755011092538 1.2127926363896266 0.872640475931855 1.107681864628899 0.8845489650338642 1.0 14.598572226731958 -5.269592658502183 23.92653179010847 1.0523063824399403 0.9139903787469474 0.20752206227043324 0.10039395649289727 431.68923789293075 1266837.322967294 0.025917994882502862 0.0555823156369475 5.375357354416248e-06 5.269592658502183 -0.1383160036929929 STPLSQPSANGVQT(ph)EGLDYDR ddPTM_PC-9_Lapatinib_30min_R1 1 STPLSQPSANGVQTEGLDYDR 21 0 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 1 S(0.131)T(0.032)PLS(0.002)QPS(0.001)ANGVQT(0.823)EGLDY(0.012)DR 109.6 0.00010668 18668000.0 2388.9 3877.7 6315.4 4276.6 5803.9 5499.0 6711.2 6498.6 8274.6 5695.1 True False 2354.833847929393 3868.7214238951756 5796.172190148987 4591.115430319386 5462.526012906426 5263.820588795094 7058.673097846204 6800.54868030568 7342.627412599119 6679.490446756252 0.3525469295450473 0.5791940949288932 0.8677566404730426 0.687345160071149 0.8178057976801483 0.7880572074702724 1.0567682002261256 1.0181238725490231 1.0992795739628471 1.0 12.705522333772004 -4.8782735192599675 0.37306077442217633 1.0685207658068068 3.159523980586215e-17 0.8193914926009054 0.09528147302000337 2.5398303048867445 0.2972304599287039 0.09202478198534735 1.2199286795413002 1.3235077256753428e-05 4.8782735192599675 -1.0685207658068068 down STPS(ph)PTPVESSDPK ddPTM_PC-9_AZD4547_30min_R2 2 STPSPTPVESSDPK 14 0 Q9NW07 Q9NW07 ZNF358 Zinc finger protein 358 1 S(0.006)T(0.006)PS(0.897)PT(0.071)PVES(0.008)S(0.011)DPK;S(0.008)T(0.002)PS(0.818)PT(0.17)PVES(0.001)SDPK 143.64 0.00016779 31179000.0 148058.0 161124.0 167591.0 228020.0 215202.0 196095.0 164165.0 202920.0 164196.0 177920.0 True False 195137.3642022875 213204.1820484501 165368.63383798604 175453.5118738822 185324.91695691505 183833.1486507182 178775.3669702551 171563.37663771532 172875.06534722238 171691.07495463308 1.1365609089106687 1.2417895461647397 0.9631754817871712 1.021913992443948 1.0794091481219075 1.0707204710512384 1.0412618536956213 0.9992562320612676 1.0068960509036486 1.0 17.389455519872634 -5.258997163781272 24.999438674738045 1.0271593344993397 1.1891752331801009 0.7288952703956504 0.040510863921099746 107.15207065679151 1096831.6869139213 0.01075132178416272 0.025848636367676918 5.508112935411495e-06 5.258997163781272 0.16201589868076116 STPS(ph)PTPVESSDPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STPSPTPVESSDPK 14 0 Q9NW07 Q9NW07 ZNF358 Zinc finger protein 358 1 STPS(0.791)PT(0.209)PVESSDPK;S(0.122)T(0.18)PS(0.665)PT(0.033)PVESSDPK;S(0.002)T(0.002)PS(0.889)PT(0.107)PVESSDPK;S(0.039)T(0.007)PS(0.737)PT(0.188)PVES(0.023)S(0.006)DPK 147.39 0.0001367 27899100.0 150433.0 164747.0 131969.0 176488.0 183520.0 161409.0 182725.0 142159.0 123388.0 133380.0 True False 175898.33571281563 181101.99338500734 135115.64145521942 166599.9495418165 147560.57340934325 152944.4278956951 165415.96518556104 138427.47687991077 125192.31607283762 157560.73816450068 1.1163843084383729 1.1494106685126628 0.8575463851543552 1.0573696942691297 0.9365313664326909 0.9707013922212908 1.0498552311481248 0.8785658057490572 0.7945654325516746 1.0 17.265548555474304 -1.522878757621884 0.43377015199730284 0.9254873022465242 5.528119379199148 0.3524946340710571 0.08822149699392647 91.62610907856812 1.1428305330146917 0.05804026475750455 369.5173920055437 0.02999999914747618 1.522878757621884 4.602632076952624 STPS(ph)PTPVESSDPK ddPTM_PC-9_Lapatinib_30min_R1 2 STPSPTPVESSDPK 14 0 Q9NW07 Q9NW07 ZNF358 Zinc finger protein 358 1 STPS(0.987)PT(0.013)PVESSDPK;STPS(0.584)PT(0.414)PVES(0.001)SDPK 168.93 0.00033107 28328000.0 170462.0 152658.0 145807.0 133791.0 146548.0 142489.0 136510.0 133349.0 141802.0 103773.0 True False 168031.18062109753 152304.5297802799 133819.31129129606 143630.43645369253 137928.33476445358 136395.07762808207 143577.81985144017 139544.88135445805 125830.76551874164 121710.02478116938 1.3805862000538744 1.2513721039340715 1.0994929261734914 1.1801035840057983 1.1332536905850128 1.120656066526286 1.1796712728436984 1.1465356416232364 1.0338570363861252 1.0 16.893088476559484 -1.5228787735314924 0.6964880273324007 1.1111610288528837 35.04108427666383 0.7077599759810667 0.0553576530439383 155.3495859416305 0.8364159214344616 0.02145998771462518 8203.242133656235 0.029999998048479425 1.5228787735314924 33.92992324781095 STPSES(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 STPSESPR 8 0 A8K855-2;A8K855 A8K855-2 EFCAB7 EF-hand calcium-binding domain-containing protein 7 1 STPS(0.011)ES(0.989)PR 70.816 0.037106 4867800.0 23830.0 21798.0 29541.0 48679.0 31368.0 30409.0 26864.0 27272.0 24058.0 31715.0 True False 31407.444305208173 28843.777216877133 29149.26703825348 37456.80863305283 27013.09465109292 28507.520422854748 29254.843957536206 23057.73904821491 25329.656764619565 30604.667503294713 1.026230534993626 0.9424633420301654 0.9524451469735931 1.2238920298356601 0.8826462384597008 0.9314762338060298 0.9558948469015979 0.7534059648167278 0.8276403186505041 1.0 14.901464073981998 -6.414511133460578 22.90512919920096 0.8846531780366651 1.0272872719260018 0.34820314641660977 0.09618008006066492 17.570366521573025 3697.38271311601 0.030713074662010075 0.03482532965703633 3.8502494415259603e-07 6.414511133460578 0.14263409388933668 STPSES(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STPSESPR 8 0 A8K855-2;A8K855 A8K855-2 EFCAB7 EF-hand calcium-binding domain-containing protein 7 1 STPS(0.007)ES(0.993)PR 78.113 0.022587 2705000.0 14832.0 13760.0 18208.0 21807.0 29112.0 25239.0 20659.0 20608.0 18235.0 21312.0 True False 17342.764654646828 15126.001863328034 18642.14777422453 20585.224489247914 23407.712582240583 23915.42240927981 18702.029961792377 20067.061835980898 18501.652377769282 25175.696894300814 0.6888692983340144 0.6008176030571851 0.7404818961911109 0.8176625487538312 0.9297741659552446 0.9499408302255855 0.7428604673909177 0.7970806893740292 0.7349013000691799 1.0 14.61974409391006 -5.600989723528371 2.687896931942715 0.8486197874086505 0.646020029763163 0.49901872825928617 0.08455543000143408 0.23724276642985254 3.442239684101015 0.025049398089487293 0.05161128065401902 2.506168554419571e-06 5.600989723528371 -0.20259975764548754 STPSHGSVSSLNSTGS(ph)LSPK ddPTM_PC-9_Lapatinib_30min_R1 1 STPSHGSVSSLNSTGSLSPK 20 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;M0R2S2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 STPSHGSVS(0.067)S(0.271)LNS(0.111)T(0.184)GS(0.307)LS(0.06)PK 101.23 0.0002799 3311300.0 3456.8 2523.8 15175.0 3053.4 7550.3 11803.0 5403.1 7782.6 17596.0 5303.5 True False 3407.505398100518 2517.956296161809 13927.37007719398 3277.9572218438043 7106.206198460932 11298.213204136833 5682.846080428659 8144.208007778135 15614.153185905549 6220.2029085304575 0.5478125791406943 0.40480291932416784 2.2390539797494107 0.5269855774878945 1.1424396121733262 1.816373737365116 0.9136110451694652 1.3093154881827207 2.5102321283590476 1.0 12.602745927776157 -5.21906461078611 24.981885725291956 1.3958130441891397 0.47630688805944105 0.3019363786557424 0.5792935918259565 597.41333167008 352200.9061093255 0.14328119889372865 0.3790799438011221 6.038587855150673e-06 5.21906461078611 -0.9195061561296987 STPSHGSVSSLNSTGSLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 STPSHGSVSSLNSTGSLSPK 20 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;M0R2S2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 STPSHGSVSSLNS(0.008)T(0.016)GS(0.144)LS(0.833)PK;STPSHGSVS(0.001)S(0.001)LNS(0.162)T(0.162)GS(0.248)LS(0.427)PK 121.97 5.202999999999999e-06 37525000.0 4120.9 6066.08 41226.0 149583.0 72075.0 49843.0 22185.2 66776.0 25836.2 51881.0 True False 5431.260479955193 8026.821731340213 40679.3163034101 115098.95038431248 62068.63035506003 46726.30933067013 24159.639821572826 56457.30355982688 27201.848786352308 50064.66198134741 0.10848491261118905 0.160329090693367 0.8125355229316438 2.2990058422284942 1.2397692883292597 0.9333191812636016 0.4825687194407501 1.1276877007750732 0.5433343142611629 1.0 15.611505019441246 -5.335349936520806 4.293557426595385 1.0979885637300082 0.1275662918288625 0.3866884505914261 0.47052100301039923 0.22448635688468818 7.830327016428893 0.1347795080067049 0.3062934698579209 4.6200860396668046e-06 5.335349936520806 -0.9704222719011457 STPSHGSVSSLNSTGSLS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STPSHGSVSSLNSTGSLSPK 20 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;M0R2S2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 STPSHGSVSSLNS(0.001)T(0.002)GS(0.019)LS(0.977)PK 162.2 1.6243e-06 15077000.0 4909.8 6790.7 24669.0 21016.0 34384.0 31609.0 15199.0 14047.0 23569.0 10560.0 True False 5740.932167029731 7464.835817827159 25257.202517703467 19838.54165479131 27646.70202760927 29951.368395535697 13759.240688769169 13678.281134026767 23913.65203683268 12474.444407085997 0.46021545967759864 0.5984102837948299 2.0247156260808166 1.590334688054099 2.2162672040050784 2.401018227194318 1.1029942689033392 1.0965042359928223 1.9170113919661818 1.0 13.606687941084614 -5.247073868677554 21.571856600369316 1.6947733317373719 0.5293106957558215 0.4918105467426359 0.46263205486395703 110.0358897172152 165228.45503602698 0.12336620400325371 0.32142288388013407 5.66142986201766e-06 5.247073868677554 -1.1654626359815503 STPSHGSVSSLNSTGSLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 STPSHGSVSSLNSTGSLSPK 20 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;M0R2S2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 STPSHGSVSSLNS(0.059)T(0.068)GS(0.128)LS(0.745)PK;STPSHGSVSSLNSTGSLS(1)PK 229.89 1.7612e-36 33005000.0 66998.0 43597.0 267030.0 69383.0 145651.0 181560.0 79391.0 108327.0 281130.0 67134.0 True False 66042.5962340714 43496.05382509168 245075.8241656079 74485.65727490286 137084.09454088358 173795.10203703164 83501.47751685366 113360.26788715627 249466.17896985845 78738.0224495681 0.8387637151589862 0.5524148622471565 3.112547363284105 0.9459934979013614 1.7410152081059223 2.2072576454196295 1.0604975197381488 1.4397144398662514 3.168306381197752 1.0 16.264772858390977 STPSSST(ph)PSSR ddPTM_PC-9_Lapatinib_30min_R1 1 STPSSSTPSSR 11 0 H3BUV9;Q96S82 H3BUV9 UBL7 Ubiquitin-like protein 7 1 S(0.017)T(0.001)PS(0.028)S(0.028)S(0.169)T(0.743)PS(0.011)S(0.002)R 74.962 0.042 0.0 3026.3 5288.4 5020.9 3921.4 6667.8 5997.8 6530.2 5799.5 6556.6 5641.4 True False 2983.1444070445514 5276.155034718325 4608.1009832344835 4209.79283740692 6275.613113399178 5741.288075554684 6868.301803486 6068.965942115652 5818.126663941137 6616.508473307005 0.45086383839444283 0.7974228486223404 0.696455086821842 0.6362559429025892 0.9484780588911655 0.8677217143629113 1.0380553174222937 0.9172460016638223 0.879334876908753 1.0 12.691854393374799 -6.263162313559466 24.990462777710473 0.938776555730116 0.6597764978428006 0.7066826800450019 0.09339910493187757 88.26742423704955 1280281.827644527 0.027681933776830675 0.03302832182091972 5.455539272328303e-07 6.263162313559466 -0.2790000578873154 STPVPEVVQELPLT(ph)SPVDDFRQPR ddPTM_PC-9_AZD4547_30min_R2 2 STPVPEVVQELPLTSPVDDFRQPR 24 1 A0A0G2JMZ8;Q16625-5;Q16625-4;Q16625-2;Q16625-3;Q16625 A0A0G2JMZ8 OCLN Occludin 1 STPVPEVVQELPLT(0.5)S(0.5)PVDDFRQPR;STPVPEVVQELPLT(0.5)S(0.5)PVDDFRQPR 122.22 3.2175e-06 4214200.0 7397.5 15829.7 17494.3 20629.7 16171.2 12755.400000000001 19853.1 27258.5 19246.5 17208.6 True False 9749.751122441345 20946.340958344805 17262.314151427447 15873.841390687765 13926.108015230624 11957.802821588386 21619.987439449153 23046.325163015747 20263.8306974915 16606.13215189019 0.587117519797142 1.26136181301921 1.0395144392165137 0.9559023886776024 0.8386123805262797 0.72008356384345 1.3019279409376652 1.3878201710199267 1.2202619196418338 1.0 14.019428463982242 -7.279658974763807 24.738235999251305 1.2598208940825202 0.9228712394026984 0.3979952568534876 0.19428180299358047 748.2082899848865 1015899.12094228 0.08141377578524742 0.05501334309631351 5.2521972170398905e-08 7.279658974763807 -0.33694965467982174 STPVPEVVQELPLTS(ph)PVDDFRQPR ddPTM_PC-9_AZD4547_30min_R2 2 STPVPEVVQELPLTSPVDDFRQPR 24 1 A0A0G2JMZ8;Q16625-5;Q16625-4;Q16625-2;Q16625-3;Q16625 A0A0G2JMZ8 OCLN Occludin 1 STPVPEVVQELPLT(0.246)S(0.754)PVDDFRQPR;STPVPEVVQELPLT(0.03)S(0.97)PVDDFRQPR 100.47 1.6471e-06 2035400.0 11352.4 14231.2 17287.8 24764.2 18679.3 15039.1 16289.4 27554.6 19530.2 16088.2 True False 14962.227055411042 18831.157093716014 17058.55247635214 19055.196293076006 16086.00162318797 14098.702699574287 17739.12504325084 23296.669711716848 20562.52650030648 15524.957014866959 0.9637532033797558 1.2129603370677924 1.0987825898658903 1.227391243327014 1.0361382390807103 0.9081315127683209 1.142619913618025 1.5005947964562842 1.32448202469195 1.0 13.922301653500899 -7.540941759027586 24.674513097406106 1.311844667603943 1.0819789592912068 0.25857849939378796 0.1476205480193856 242.38399028645233 331097.8195839785 0.06786200772625661 0.039189681137561196 2.8777843135347336e-08 7.540941759027586 -0.22986570831273623 STPVPEVVQELPLTS(ph)PVDDFRQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 STPVPEVVQELPLTSPVDDFRQPR 24 1 A0A0G2JMZ8;Q16625-5;Q16625-4;Q16625-2;Q16625-3;Q16625 A0A0G2JMZ8 OCLN Occludin 1 STPVPEVVQELPLT(0.288)S(0.712)PVDDFRQPR;STPVPEVVQELPLT(0.254)S(0.746)PVDDFRQPR;STPVPEVVQELPLT(0.434)S(0.566)PVDDFRQPR 115.34 9.617100000000001e-09 5024200.0 12532.2 8927.7 9970.6 13455.6 21428.6 15067.4 18135.0 20062.0 16600.3 16694.0 True False 14653.65393776733 9813.983054886176 10208.336917711065 12701.726355643783 17229.819656492204 14277.239019358247 16417.121513969916 19535.393757446072 16843.047982817843 19720.490050368724 0.7430674339400275 0.4976541165975071 0.5176512800461668 0.644087764715882 0.8737013944625605 0.7239799306656326 0.832490545216596 0.9906140114951559 0.8540887138097727 1.0 14.267407782403831 -6.6878203515272245 0.735717246070921 0.9487399101437795 0.5646459926232105 0.6806559369086904 0.09452616277312413 0.40620132142630216 0.48678437813517483 0.06741400058585251 0.07254080932860094 2.052010829665852e-07 6.6878203515272245 -0.384093917520569 STPVPEVVQELPLTS(ph)PVDDFRQPR ddPTM_PC-9_Lapatinib_30min_R1 1 STPVPEVVQELPLTSPVDDFRQPR 24 1 A0A0G2JMZ8;Q16625-5;Q16625-4;Q16625-2;Q16625-3;Q16625 A0A0G2JMZ8 OCLN Occludin 1 STPVPEVVQELPLT(0.262)S(0.738)PVDDFRQPR 67.218 0.0038629 0.0 3833.9 3357.4 3377.4 2198.8 2296.7 3126.3 2659.8 2402.2 3020.9 1238.4 True False 3779.2278829488496 3349.626146578043 3099.723209141019 2360.5070869817782 2161.6126214859305 2992.5954367612476 2797.511429498648 2513.8149816622513 2680.654430512734 1452.4557899357253 2.6019572568994267 2.306181138034 2.1341256860411493 1.6251834330091632 1.488246758671799 2.060369380945961 1.9260561656217052 1.7307342495935754 1.8456013939201272 1.0 10.504278535995041 -1.5228787452803376 0.060969367542401065 1.300125454530395e-13 5.843425522636688 0.6597235674535442 0.2486998596948572 241.74455926583144 1.1042259783063144 21.16734585624809 125.03353693342841 0.029999999999999995 1.5228787452803376 5.843425522636558 STQIENQHQGAQDT(ph)SDLMSPSKR ddPTM_PC-9_AZD4547_30min_R2 1 STQIENQHQGAQDTSDLMSPSKR 23 1 H0YBW3;Q9NVR2 H0YBW3 INTS10 Integrator complex subunit 10 1 STQIENQHQGAQDT(0.341)S(0.341)DLMS(0.233)PS(0.085)KR 65.598 0.00080991 4013500.0 7425.9 8466.9 10843.0 16600.0 15453.0 10451.0 9591.9 12403.0 10042.0 13720.0 True False 9787.181731684652 11203.659845746253 10699.214735309657 12773.126467443391 13307.617688196224 9797.4973178748 10445.56051802753 10486.401342586147 10572.799618850682 13239.666976042987 0.7392317155253554 0.8462191583836011 0.808118116163326 0.9647619151264307 1.005132358108115 0.7400108579470503 0.788959460757483 0.7920441927701928 0.7985699064774086 1.0 13.69257921332194 -4.520386414062713 1.9292031933647849 0.8562444137876074 0.6202923445687826 0.1371719805262216 0.09080922055660086 4.7008693456841755 9.913696764183129 0.02575155869113551 2.527347431030275 3.017265909581027e-05 4.520386414062713 -0.23595206921882483 STQIENQHQGAQDT(ph)SDLMSPSKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STQIENQHQGAQDTSDLMSPSKR 23 1 H0YBW3;Q9NVR2 H0YBW3 INTS10 Integrator complex subunit 10 1 STQIENQHQGAQDT(0.459)S(0.079)DLMS(0.231)PS(0.231)KR 61.086999999999996 0.0014165 28117000.0 19658.0 22944.0 22893.0 27067.0 28011.0 24713.0 26660.0 28388.0 24277.0 23352.0 True False 22985.711136801998 25221.72868838651 23438.85594218598 25550.523742397985 22522.445628645957 23417.006775249894 24134.571798314773 27642.84507957227 24632.0051974283 27585.532745669723 0.8332523917055839 0.9143100088340953 0.8496792923408494 0.9262291208209061 0.8164586066289203 0.8488872406832821 0.8748996084588336 1.0020776228768518 0.8929320098519737 1.0 14.751624222341066 -7.6883666642825546 7.761984760251075 0.9603443707694728 0.8667902391543897 0.5322268862362709 0.042382898206214346 0.184648855279182 16.877697902219296 0.019120246617334496 0.010946745296182649 2.049431163248393e-08 7.6883666642825546 -0.09355413161508308 STQIENQHQGAQDTS(ph)DLMSPSKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STQIENQHQGAQDTSDLMSPSKR 23 1 H0YBW3;Q9NVR2 H0YBW3 INTS10 Integrator complex subunit 10 1 STQIENQHQGAQDT(0.129)S(0.535)DLMS(0.269)PS(0.067)KR 83.395 2.2222e-05 3981900.0 7799.1 6774.4 7745.9 10083.0 9429.5 10409.0 11917.0 12377.0 10254.0 9008.7 True False 9119.333590753507 7446.9176615501065 7930.591632489336 9518.082199527062 7581.857165232124 9863.133716002756 10788.135488391485 12052.116864515494 10403.945351337883 10641.905997170044 0.8569267190650408 0.6997729225883439 0.7452228608858492 0.8943963799396615 0.7124529353339838 0.9268202254958479 1.013740911755876 1.132514877289882 0.977639283235969 1.0 13.377468944524287 -7.024882571031787 2.8918663742425075 1.041839898208217 0.7814814038255317 0.7420713432890809 0.06901957455845699 0.12884287389471422 2.169556702274885 0.02741086119853206 0.021751936420956873 9.44316175600892e-08 7.024882571031787 -0.26035849438268543 STQIENQHQGAQDTSDLMS(ph)PSKR ddPTM_PC-9_AZD4547_30min_R2 6 STQIENQHQGAQDTSDLMSPSKR 23 1 H0YBW3;Q9NVR2 H0YBW3 INTS10 Integrator complex subunit 10 1 STQIENQHQGAQDT(0.267)S(0.058)DLMS(0.338)PS(0.338)KR;STQIENQHQGAQDT(0.057)S(0.057)DLMS(0.662)PS(0.225)KR;STQIENQHQGAQDT(0.111)S(0.111)DLMS(0.389)PS(0.389)KR;STQIENQHQGAQDT(0.118)S(0.036)DLMS(0.656)PS(0.19)KR;STQIENQHQGAQDT(0.008)S(0.008)DLMS(0.929)PS(0.055)KR;STQIENQHQGAQDT(0.033)S(0.012)DLMS(0.797)PS(0.158)KR 89.917 5.5568999999999996e-05 109701100.0 122385.9 104619.9 130585.3 189593.0 157577.0 143411.0 130447.0 146198.0 112577.4 144745.0 True False 161302.0704151397 138436.23672134883 128853.65359908075 145885.26303265052 135700.15352701047 134443.48749916223 142056.53029067622 123606.45839582437 118528.01153268284 139677.52160694942 1.1548176725890187 0.9911132094032027 0.9225081610602536 1.0444433818289645 0.9715246373634033 0.9625277278149617 1.0170321513179572 0.8849416640112732 0.8485832950717653 1.0 17.09174034002679 -4.773177971513106 3.5882583805050117 0.9581802315687381 1.179317408491486 0.5263794923297029 0.05616212189339767 0.23969378329648414 5.16472309143375 0.014836284196061405 0.14558694967339458 1.6858620267389094e-05 4.773177971513106 0.2211371769227478 STQIENQHQGAQDTSDLMS(ph)PSKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STQIENQHQGAQDTSDLMSPSKR 23 1 H0YBW3;Q9NVR2 H0YBW3 INTS10 Integrator complex subunit 10 1 STQIENQHQGAQDT(0.015)S(0.011)DLMS(0.806)PS(0.168)KR;STQIENQHQGAQDT(0.172)S(0.05)DLMS(0.389)PS(0.389)KR 95.523 3.5425e-06 22785600.0 36509.0 37777.0 36715.0 50729.0 47281.0 53728.0 57481.0 53047.0 45944.0 38502.0 True False 42689.252614381134 41527.250900504594 37590.42484241287 47886.81859563701 38016.6274594984 50910.40909726159 52035.98355359833 51654.57245794245 46615.84408249148 45482.10781833571 0.9385944201374796 0.9130458743550854 0.8264881872352148 1.0528715772564055 0.8358589626352438 1.1193502574816356 1.1440978892499896 1.135711930156376 1.0249270827263357 1.0 15.473011495446155 -6.773017567716826 24.99063361267345 1.0970044921136082 0.9162768151769947 0.5805933613935936 0.07246800477830602 147.6714365263862 318735.5727892635 0.02452413294572686 0.021807637526497104 1.6864848037374353e-07 6.773017567716826 -0.1807276769366135 STQIENQHQGAQDTSDLMS(ph)PSKR ddPTM_PC-9_Lapatinib_30min_R1 5 STQIENQHQGAQDTSDLMSPSKR 23 1 H0YBW3;Q9NVR2 H0YBW3 INTS10 Integrator complex subunit 10 1 STQIENQHQGAQDT(0.019)S(0.011)DLMS(0.485)PS(0.485)KR;STQIENQHQGAQDT(0.009)S(0.009)DLMS(0.91)PS(0.071)KR;STQIENQHQGAQDT(0.025)S(0.025)DLMS(0.913)PS(0.038)KR;STQIENQHQGAQDT(0.011)S(0.011)DLMS(0.489)PS(0.489)KR;STQIENQHQGAQDT(0.005)S(0.015)DLMS(0.728)PS(0.252)KR 106.39 7.9504e-07 53743400.0 121192.0 96932.0 113017.0 108075.0 118448.0 117248.0 103969.0 104515.0 118824.0 94470.0 True False 119463.77985610903 96707.5599094845 103725.1785182361 116023.19602763103 111481.12151772792 112233.57635843748 109352.00609577599 109371.14845076621 105440.78984780876 110799.01362663775 1.0782025574584009 0.8728196826314936 0.9361561544921462 1.047150080402316 1.0061562632081607 1.012947432335759 0.9869402489832826 0.9871130154580342 0.951640149100201 1.0 16.757585512481924 -5.732091074596565 24.9998611097313 0.998708312927343 0.9534354777014343 0.08498184377927787 0.052401492133487784 430.65202792238995 366840.5108254566 0.013853659820004964 0.02399047136327681 1.853142965596647e-06 5.732091074596565 -0.045272835225908636 STS(ph)ADSASSSDTSR ddPTM_PC-9_AZD4547_30min_R2 1 STSADSASSSDTSR 14 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.018)T(0.136)S(0.772)ADS(0.034)AS(0.034)S(0.006)SDTSR 104.41 0.0046911 0.0 3067.8 3396.5 5587.7 4718.6 4365.1 4909.5 4094.8 6065.5 4264.3 5500.2 True False 4043.296585795952 4494.3522028224215 5513.60344706168 3630.799671643279 3759.081212110614 4602.508188891619 4459.229267321295 5128.216346323976 4489.702192259006 5307.639672130584 0.7617880706986462 0.846770406518253 1.0388051540146128 0.6840704900726258 0.7082397156402387 0.8671478233645971 0.8401529762345903 0.966195270046547 0.8458943088833981 1.0 12.373854716245175 -7.643765017872849 5.097616325360253 0.9290091754781312 0.8207948971459589 0.2240317580899428 0.09932137855645395 0.3751195054621962 15.105559417210024 0.05093831130186399 0.028506657725165325 2.27109333167312e-08 7.643765017872849 -0.10821427833217234 STS(ph)ADSASSSDTSR ddPTM_PC-9_Lapatinib_30min_R1 1 STSADSASSSDTSR 14 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.02)T(0.12)S(0.549)ADS(0.189)AS(0.06)S(0.06)S(0.002)DTSR 99.834 0.009398100000000001 0.0 4626.0 3515.8 4762.4 4164.1 5030.1 4134.6 3369.3 4619.9 4048.4 4387.9 True False 4560.0323916955 3507.6593811101097 4370.853855395623 4470.341805030391 4734.2394075571 3957.7727962233466 3543.7458678884855 4834.557419774139 3592.4265604580596 5146.342668490766 0.8860724373475874 0.6815829428899607 0.8493126355842594 0.8686444127400825 0.9199230817922739 0.7690457187111515 0.688595007399252 0.9394161506917178 0.6980542866788128 1.0 12.329331806575091 -11.074330475734316 3.0492424036282144 1.0080471441004575 0.8123076460919654 0.2738749556954949 0.09221783402160189 55965298.268341795 61983331.921843685 3676641.376479142 0.022009251281189357 8.426932675472993e-12 11.074330475734316 -0.1957394980084921 STS(ph)EGAWPQLPSGLSMMR ddPTM_PC-9_AZD4547_30min_R2 7 STSEGAWPQLPSGLSMMR 18 0 G3V1A6;P57764 G3V1A6 GSDMD Gasdermin-D 1 S(0.011)T(0.038)S(0.951)EGAWPQLPSGLSMMR;S(0.028)T(0.121)S(0.85)EGAWPQLPSGLSMMR;S(0.013)T(0.013)S(0.975)EGAWPQLPSGLSMMR;S(0.003)T(0.003)S(0.824)EGAWPQLPS(0.136)GLS(0.034)MMR;S(0.045)T(0.168)S(0.787)EGAWPQLPSGLSMMR;S(0.037)T(0.037)S(0.926)EGAWPQLPSGLSMMR;S(0.137)T(0.137)S(0.726)EGAWPQLPSGLSMMR 141.85 0.00015471 91993500.0 103182.1 130407.0 171161.0 311426.0 246544.0 200530.0 192309.0 265968.0 191307.0 211766.0 True False 135991.86147899358 172558.51250212386 168891.29330538944 239631.54718373643 212315.62125921523 187990.8273996201 209424.1284481025 224868.75693662418 201419.09745901907 204352.1367965536 0.665478049854613 0.8444174609924318 0.8264718732720283 1.1726402813311705 1.038969421056702 0.9199357067980047 1.0248198611037693 1.1003983636368642 0.9856471315469798 1.0 17.640697803333303 -5.6148265034536795 6.354539121951401 1.0333521913463155 0.7742950928330651 0.709484064706256 0.07567377381559302 0.114609516215467 6.502860382650034 0.021118743578313365 0.036932183680115624 2.4275796965716455e-06 5.6148265034536795 -0.25905709851325043 STS(ph)EGAWPQLPSGLSMMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STSEGAWPQLPSGLSMMR 18 0 G3V1A6;P57764 G3V1A6 GSDMD Gasdermin-D 1 S(0.07)T(0.07)S(0.86)EGAWPQLPSGLSMMR;S(0.05)T(0.05)S(0.899)EGAWPQLPSGLSMMR;S(0.043)T(0.043)S(0.785)EGAWPQLPS(0.063)GLS(0.067)MMR;S(0.128)T(0.128)S(0.744)EGAWPQLPSGLSMMR 114.58 0.00012315 65444400.0 118138.0 121692.0 132195.0 145294.0 164306.0 149308.0 122626.0 126503.0 117421.0 92454.0 True False 138136.43006814114 133772.7775255899 135347.03015232953 137153.6482295037 132111.41878049003 141478.0256382879 111009.97754464176 123182.43029100815 119138.05998629252 109215.17833453894 1.2648098201608298 1.224855185566132 1.2392694148952965 1.2558112372383439 1.2096433920184355 1.2954062594204996 1.0164336060012202 1.1278874618845183 1.0908562509632005 1.0 16.736813845220816 -7.260843124373479 24.99999998773625 1.0694516149037967 1.2454075091461432 0.8407401859810076 0.04028779197908195 20.977167355092103 879562.3094697688 0.01536168294054324 0.01118065888076089 5.4847504901427745e-08 7.260843124373479 0.17595589424234648 STS(ph)EGAWPQLPSGLSMMR ddPTM_PC-9_Lapatinib_30min_R1 8 STSEGAWPQLPSGLSMMR 18 0 G3V1A6;P57764 G3V1A6 GSDMD Gasdermin-D 1 S(0.036)T(0.036)S(0.927)EGAWPQLPS(0.001)GLSMMR;S(0.014)T(0.014)S(0.971)EGAWPQLPSGLS(0.001)MMR;S(0.133)T(0.133)S(0.733)EGAWPQLPSGLSMMR;S(0.015)T(0.043)S(0.937)EGAWPQLPS(0.002)GLS(0.003)MMR;S(0.158)T(0.158)S(0.683)EGAWPQLPSGLSMMR;S(0.029)T(0.029)S(0.742)EGAWPQLPS(0.173)GLS(0.028)MMR;S(0.033)T(0.042)S(0.92)EGAWPQLPS(0.004)GLS(0.001)MMR;S(0.139)T(0.139)S(0.718)EGAWPQLPS(0.002)GLS(0.002)MMR 94.61 0.00075806 61000700.0 233003.0 223395.0 266142.0 188672.0 209990.0 199698.0 164554.0 182843.0 192434.0 154372.0 True False 229680.33449248289 222877.74260284778 244260.8320978291 202547.56827134185 197638.80105622453 191157.38205877453 173073.8009510943 191338.55328118821 170760.0565001449 181054.99451223965 1.2685666866646756 1.2309947218152042 1.3490974538198481 1.1187074337109726 1.0915954104920524 1.0557973425353475 0.9559184015738058 1.0567979844834017 0.943139165865989 1.0 17.466068449420767 -6.206485978894831 1.3152772946302793 0.9990473173285369 1.280800978141897 0.8441304125615465 0.05097870823699822 0.1577817881225293 0.5531317248371821 0.019083332636833473 0.02856448296135008 6.216043157919743e-07 6.206485978894831 0.28175366081336006 STS(ph)FGVPNANSIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STSFGVPNANSIK 13 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6;P53814-2;H7BZZ8;B5MCI0;A0A096LNK9 A0A087WVP4 SMTN Smoothelin 1 S(0.011)T(0.011)S(0.978)FGVPNANSIK;S(0.001)T(0.003)S(0.996)FGVPNANSIK;S(0.003)T(0.003)S(0.994)FGVPNANSIK;S(0.003)T(0.049)S(0.948)FGVPNANSIK 174.94 0.00017243 22490900.0 182372.0 165184.0 153245.0 185143.0 205344.0 197303.0 189919.0 214630.0 185407.0 123066.0 True False 213243.9775888114 181582.37585697495 156898.9419848992 174770.03795170473 165108.31727423775 186956.0833479192 171928.49742551133 208996.1899192832 188118.22661941705 145376.89161008032 1.4668354456274895 1.249045662250108 1.0792564089602528 1.202185822080036 1.1357260115113734 1.2860096352132748 1.1826397959219397 1.4376163061722222 1.294003637964516 1.0 17.149438438267566 STS(ph)FGVPNANSIK ddPTM_PC-9_Lapatinib_30min_R1 3 STSFGVPNANSIK 13 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6;P53814-2;H7BZZ8;B5MCI0;A0A096LNK9 A0A087WVP4 SMTN Smoothelin 1 S(0.072)T(0.072)S(0.856)FGVPNANSIK;ST(0.132)S(0.868)FGVPNANSIK;S(0.003)T(0.011)S(0.986)FGVPNANSIK 110.92 0.00062278 12781300.0 141578.0 118010.0 137245.0 114762.0 133545.0 130353.0 126870.0 127160.0 131191.0 120752.0 True False 139559.0717577746 117736.75509551275 125961.24588102032 123201.98031480922 125690.14565957196 124778.10605768429 133438.7078203223 133068.31782040285 116414.88807752526 141623.82230807375 0.9854208810590657 0.8313343982441065 0.8894071903172993 0.869924129337566 0.8874929627740076 0.8810530885563514 0.942205242350073 0.9395899337537993 0.8220007494522242 1.0 17.111704433607997 -7.2435224364573285 23.730465943118805 0.9209148109645715 0.8869116620668586 0.08487601458206218 0.05473834631804923 1122.7022613993306 1486987.3634709097 0.019938338173937302 0.015400578175817558 5.70791587259539e-08 7.2435224364573285 -0.03400314889771294 STS(ph)FRGGMGSGGLATGIAGGLAGMGGIQNEK ddPTM_PC-9_AZD4547_30min_R2 9 STSFRGGMGSGGLATGIAGGLAGMGGIQNEK 31 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.069)T(0.229)S(0.587)FRGGMGS(0.062)GGLAT(0.052)GIAGGLAGMGGIQNEK;S(0.057)T(0.057)S(0.873)FRGGMGS(0.011)GGLAT(0.001)GIAGGLAGMGGIQNEK;S(0.135)T(0.135)S(0.595)FRGGMGS(0.11)GGLAT(0.024)GIAGGLAGMGGIQNEK;S(0.041)T(0.113)S(0.386)FRGGMGS(0.348)GGLAT(0.113)GIAGGLAGMGGIQNEK;S(0.042)T(0.146)S(0.461)FRGGMGS(0.322)GGLAT(0.029)GIAGGLAGMGGIQNEK;S(0.123)T(0.123)S(0.407)FRGGMGS(0.337)GGLAT(0.009)GIAGGLAGMGGIQNEK;S(0.128)T(0.128)S(0.639)FRGGMGS(0.1)GGLAT(0.006)GIAGGLAGMGGIQNEK;S(0.19)T(0.19)S(0.597)FRGGMGS(0.016)GGLAT(0.007)GIAGGLAGMGGIQNEK;S(0.195)T(0.195)S(0.597)FRGGMGS(0.011)GGLAT(0.003)GIAGGLAGMGGIQNEK 91.086 2.2058000000000004e-09 795343800.0 648741.3 391484.0 844110.0 1758805.0 1270959.0 759590.6 620027.6 725187.0 572643.9 788246.0 True False 855027.5387426907 518023.54711312574 832916.5498683249 1353339.6805163727 1094508.2811992595 712093.2797036577 675208.8552473817 613126.0122894475 602912.6874783086 760649.7474634106 1.1240752285713733 0.6810276988069915 1.095006673762671 1.7791890223186753 1.4389123047094792 0.9361644857943129 0.8876738045323037 0.8060556311680634 0.7926285251377282 1.0 19.536872770586186 -6.920539132989643 7.344323782305348 0.8632731987018536 1.2165593737703895 0.2919036749970564 0.26530316389723557 0.34736195988510643 27.14519731860835 0.10740994154467104 0.0946614422486892 1.200772870052473e-07 6.920539132989643 0.3532861750685359 STS(ph)FRGGMGSGGLATGIAGGLAGMGGIQNEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 STSFRGGMGSGGLATGIAGGLAGMGGIQNEK 31 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.105)T(0.105)S(0.361)FRGGMGS(0.325)GGLAT(0.105)GIAGGLAGMGGIQNEK;S(0.092)T(0.197)S(0.512)FRGGMGS(0.176)GGLAT(0.023)GIAGGLAGMGGIQNEK;S(0.034)T(0.127)S(0.544)FRGGMGS(0.104)GGLAT(0.191)GIAGGLAGMGGIQNEK 65.093 5.9261e-05 330479400.0 101891.4 48403.200000000004 93815.0 173077.0 175220.0 225654.0 153629.0 241694.0 175063.0 122711.0 True False 119139.60157311763 53208.349810395346 96051.90539536878 163380.05681320457 140886.89882729464 213820.30699883605 139076.14894235923 235349.7885959615 177622.96518834206 144957.53292025832 0.8218931377554333 0.3670616403196201 0.6626209998221154 1.1270891103195069 0.9719184370004217 1.4750548156504526 0.9594268482677994 1.6235774978691744 1.2253448414167831 1.0 17.145270781443003 -5.8540415762074245 1.8361908734193986 1.2484746437821013 0.5627571133549575 0.5722625738729461 0.22886604707639943 0.22525957755925916 1.5496089136937576 0.06974996397754218 0.12999199297855535 1.3994533426349876e-06 5.8540415762074245 -0.6857175304271438 STS(ph)FRGGMGSGGLATGIAGGLAGMGGIQNEK ddPTM_PC-9_Lapatinib_30min_R1 8 STSFRGGMGSGGLATGIAGGLAGMGGIQNEK 31 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.066)T(0.066)S(0.609)FRGGMGS(0.145)GGLAT(0.114)GIAGGLAGMGGIQNEK;S(0.122)T(0.062)S(0.768)FRGGMGS(0.046)GGLAT(0.001)GIAGGLAGMGGIQNEK;S(0.14)T(0.14)S(0.568)FRGGMGS(0.117)GGLAT(0.034)GIAGGLAGMGGIQNEK;S(0.065)T(0.231)S(0.699)FRGGMGS(0.004)GGLAT(0.001)GIAGGLAGMGGIQNEK;S(0.041)T(0.171)S(0.767)FRGGMGS(0.008)GGLAT(0.013)GIAGGLAGMGGIQNEK;S(0.336)T(0.124)S(0.404)FRGGMGS(0.056)GGLAT(0.079)GIAGGLAGMGGIQNEK;S(0.392)T(0.129)S(0.463)FRGGMGS(0.013)GGLAT(0.003)GIAGGLAGMGGIQNEK;S(0.189)T(0.189)S(0.592)FRGGMGS(0.028)GGLAT(0.003)GIAGGLAGMGGIQNEK 93.419 1.882e-10 230128500.0 517193.0 247468.19999999998 410551.0 301883.8 377878.5 330817.5 267292.1 276273.30000000005 402130.4 307478.2 True False 509817.73297842056 246895.20258730053 376797.0815526889 324085.34170683485 355652.4295677156 316669.2066982577 281131.1770677103 289109.966103267 356838.2397311593 360625.3971810523 1.413704461647958 0.6846306569566052 1.0448434428025533 0.8986758676459149 0.9862101569878063 0.8781112178277163 0.7795656636090114 0.8016905308477735 0.9894983617917745 1.0 18.460141477133078 -4.746698997017612 24.992263739385095 0.8930867167735792 1.4137058301317091 0.6726799394961026 0.10834092541262264 460.60490339716307 780910.1301752761 0.026091908404140683 0.5776530431465884 1.7918473262313423e-05 4.746698997017612 0.5206191133581299 STS(ph)FRGGMGSGGLATGIAGGLAGMGGIQNEKETMQSLNDR ddPTM_PC-9_AZD4547_30min_R2 1 STSFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQSLNDR 40 2 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.156)T(0.156)S(0.388)FRGGMGS(0.278)GGLAT(0.022)GIAGGLAGMGGIQNEKETMQSLNDR 41.406000000000006 0.0059481000000000004 22165000.0 17459.0 4488.0 20930.0 126880.0 58656.0 25676.0 14061.0 20064.0 12269.0 22403.0 True False 23010.59883024041 5938.658232376576 20652.45452458095 97629.77627645894 50512.62687625949 24070.475661061457 15312.40176023365 16963.569824852737 12917.514292340076 21618.677788942485 1.0643851143389476 0.274700344320506 0.9553060888462042 4.51599201531162 2.336527116477756 1.113411092762251 0.708295017379168 0.7846719392584341 0.5975163892283516 1.0 14.39999066924237 -6.9450040195037355 5.804166078502369 0.7738119038422031 1.8406965316992012 0.18260895037153146 1.0645420679511355 0.393338162997827 28.04924826223293 0.43048453945668397 0.3764225112809595 1.1350003109127763e-07 6.9450040195037355 1.0668846278569981 STS(ph)FRQGPEESGLGDGTGPK ddPTM_PC-9_AZD4547_30min_R2 2 STSFRQGPEESGLGDGTGPK 20 1 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614;Q92614-5;Q92614-2 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 S(0.149)T(0.149)S(0.702)FRQGPEESGLGDGTGPK;S(0.089)T(0.089)S(0.795)FRQGPEES(0.027)GLGDGTGPK 73.91 0.0030403 31668300.0 46557.0 23446.3 61926.0 215937.0 145198.0 67292.0 45779.0 54904.0 33824.0 96529.0 True False 61361.15755424152 31024.857957613815 61104.82077827041 166156.06084339303 125039.76399991661 63084.22060228021 49853.24231432587 46419.84836840684 35611.8675869354 93149.54909114083 0.6587381061201228 0.33306503638850676 0.655986221881582 1.7837559329548665 1.3423550110540339 0.6772359202786519 0.5351957449149612 0.49833680164128347 0.3823085343343045 1.0 16.507261165081907 -6.983247614605536 24.366202075300663 0.5684493128169897 0.9557050511322547 0.14755602617644825 0.4034567801414063 366.12550759079164 532523.6610376543 0.16019179838506295 0.14123810417145638 1.0393274204933425e-07 6.983247614605536 0.38725573831526494 STS(ph)FRQGPEESGLGDGTGPK ddPTM_PC-9_Lapatinib_30min_R1 1 STSFRQGPEESGLGDGTGPK 20 1 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614;Q92614-5;Q92614-2 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 S(0.152)T(0.042)S(0.742)FRQGPEES(0.064)GLGDGTGPK 95.365 0.0025946 5871100.0 119020.0 19281.0 46013.0 38236.0 21812.0 27147.0 11361.0 11618.0 44440.0 17674.0 True False 117322.75297440536 19236.356029121107 42229.98875531642 41048.00299155684 20529.06104404194 25985.98609274784 11949.216990200068 12157.814693594219 39434.69922605377 20728.927350875325 5.659856440639759 0.9279957280717089 2.0372491079975332 1.980228030941673 0.9903580969989292 1.2536097817743823 0.5764512937856133 0.586514414750015 1.9023994130785815 1.0 14.339357843531216 -4.758847614440115 24.99997977831582 1.2559006889360467 5.659862259958909 0.8660478104131798 0.5202281384624948 25.20129911335403 243040.85213452243 0.1374297788634016 0.9128797177783866 1.742418147074778e-05 4.758847614440115 4.403961571022863 STS(ph)GPRPGCQPSSPCVPK ddPTM_PC-9_AZD4547_30min_R2 1 STSGPRPGCQPSSPCVPK 18 1 O14545 O14545 TRAFD1 TRAF-type zinc finger domain-containing protein 1 1 S(0.239)T(0.28)S(0.481)GPRPGCQPSSPCVPK 53.958 0.02104 24371000.0 19876.0 22704.0 27909.0 36105.0 28821.0 32427.0 23399.0 40057.0 22547.0 26798.0 True False 26196.154553517306 30042.62399908151 27538.908424583366 27781.5500666894 24819.701636672708 30399.3345638433 25481.465670130663 33867.111068287755 23738.788389387217 25859.810176676376 1.01300645188588 1.1617495949826313 1.0649308032980618 1.0743137662992706 0.9597789568872486 1.1755436082535995 0.9853694012461487 1.309642678616155 0.9179799939443422 1.0 14.658424064667734 -6.787380380478888 24.982509773374193 1.091288593776605 1.0623516322788737 0.0008325635923360775 0.11285016299674447 1410.3065421992967 1358187.4760013928 0.03731113768334798 0.032915065730929616 1.6316222517919775e-07 6.787380380478888 -0.028936961497731284 STS(ph)GPRPGCQPSSPCVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSGPRPGCQPSSPCVPK 18 1 O14545 O14545 TRAFD1 TRAF-type zinc finger domain-containing protein 1 1 S(0.126)T(0.126)S(0.747)GPRPGCQPS(0.001)S(0.001)PCVPK 55.126999999999995 0.019133 13654000.0 19814.0 16294.0 14714.0 16110.0 20044.0 16239.0 12385.0 16894.0 12642.0 10996.0 True False 23168.11885566156 17911.560636705464 15064.83756315575 15207.408929324689 16116.522087057923 15387.398252874309 11211.803140364902 16450.550400672615 12826.865333685719 12989.487755711902 1.7836052730773608 1.3789274044951594 1.1597714895671116 1.1707473932247632 1.240735769581904 1.1846039306752467 0.8631443634437937 1.2664510494987589 0.9874804591924979 1.0 13.665056918351752 -1.5228787463660287 0.7036395523341099 1.087943151778141 90.70450249513324 0.775208080995575 0.11417459117612465 132.68669822960885 0.6940037936210824 0.043979228665513986 18718.950757288236 0.02999999992500311 1.5228787463660287 89.6165593433551 STS(ph)LSALVR ddPTM_PC-9_AZD4547_30min_R2 2 STSLSALVR 9 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5;X6R5W5;A0A0A0MRX3 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 S(0.013)T(0.083)S(0.901)LS(0.003)ALVR;S(0.004)T(0.044)S(0.939)LS(0.013)ALVR 156.48 9.0376e-05 47223000.0 51086.0 62989.0 81688.0 107616.0 83506.0 78062.0 73959.0 75259.0 58235.0 68530.0 True False 67330.28534518945 83348.96243296973 80604.76374600895 82806.79385062576 71912.63331848278 73180.77079972645 80541.20772243224 63629.450829774265 61313.183210891235 66130.78555890862 1.0181382963493202 1.2603655276213728 1.218868989151914 1.2521670981340804 1.0874305017051966 1.1066067064111582 1.2179079235447303 0.9621759410841083 0.9271503837841769 1.0 16.013034418810427 -7.770177181903881 24.986665471488482 0.9584972669858288 1.1696113066621994 0.6054196056432761 0.07496442775717949 127.81840278377176 365503.649632955 0.04063540682774918 0.0199890312747476 1.6975509504247013e-08 7.770177181903881 0.21111403967637055 STS(ph)LSALVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 STSLSALVR 9 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5;X6R5W5;A0A0A0MRX3 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 S(0.004)T(0.019)S(0.958)LS(0.019)ALVR;ST(0.001)S(0.986)LS(0.012)ALVR;S(0.006)T(0.015)S(0.977)LS(0.002)ALVR;S(0.003)T(0.015)S(0.976)LS(0.006)ALVR;ST(0.003)S(0.995)LS(0.002)ALVR 167.93 7.3029e-05 69215400.0 88749.0 99370.8 109085.0 130149.0 164406.0 146184.0 165279.0 144079.0 156597.0 140908.0 True False 103772.45282734977 109235.67630526122 111686.00010716626 122857.17347875102 132191.82449834587 138517.8536977755 149622.57660366336 140297.07891431893 158886.93487258186 166453.50497288568 0.6234320679775034 0.6562533863318474 0.6709741565691829 0.7380870321641094 0.7941666624555558 0.8321714446345799 0.8988851068533282 0.8428604668743535 0.954542440535954 1.0 17.34475972373002 -6.161274634110573 0.31347716295555306 1.0057927417902943 0.4977268672889256 0.962022498426666 0.02377792814036992 0.5475908467248529 0.08448188076592864 0.02916241222112329 0.10048948452759297 6.898034559744806e-07 6.161274634110573 -0.5080658745013686 STS(ph)LSALVR ddPTM_PC-9_Lapatinib_30min_R1 3 STSLSALVR 9 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5;X6R5W5;A0A0A0MRX3 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 S(0.004)T(0.02)S(0.976)LSALVR;S(0.017)T(0.02)S(0.959)LS(0.004)ALVR;S(0.058)T(0.041)S(0.893)LS(0.008)ALVR 150.1 0.00023362 60532000.0 126426.0 110570.0 116252.0 94909.0 113555.0 155239.0 143468.0 133614.0 148103.0 121816.0 True False 124623.1420563113 110313.9819584007 106694.20930569743 101888.92446714255 106875.91815771977 148599.78984978376 150896.07104568457 139822.19422188817 131422.08054626998 142871.73329038278 0.8722729065169125 0.7721190148522287 0.7467831939075341 0.7131496351350073 0.7480550259756245 1.0400923011675016 1.0561646280233232 0.9786554065086024 0.9198606156695691 1.0 17.12436098656235 -6.758345169350567 24.99997256590464 1.0011961966165828 0.7660661464489931 0.8312316505150452 0.05145129818388195 33.17661074511536 268054.0544614961 0.01869210672821234 0.017937421663697703 1.744435156498046e-07 6.758345169350567 -0.2351300501675897 STS(ph)PASEKADPGAVK ddPTM_PC-9_AZD4547_30min_R2 1 STSPASEKADPGAVK 15 1 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;A0A087WYS3;Q9ULU4-4;Q9ULU4-18;Q9ULU4-8;Q9ULU4-15;Q9ULU4-17;A0A087WV57;Q9ULU4-2 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 S(0.01)T(0.064)S(0.926)PASEKADPGAVK 127.2 0.00056142 0.0 18572.0 11098.0 19761.0 35818.0 28686.0 25175.0 16184.0 17846.0 15862.0 23214.0 True False 24477.509678402253 14685.211466781462 19498.956228391984 27560.713482583582 24703.444056403096 23600.80327026104 17624.344647437698 15088.310760283186 16700.4329370852 22401.28492579168 1.0926832884581597 0.6555521933419842 0.8704391865460314 1.2303184202997037 1.1027690660708855 1.0535468544970963 0.7867559698392989 0.6735466653036177 0.7455122771934027 1.0 14.451293866426138 -7.27613605428587 19.98785398347832 0.7742487715674332 0.9943183937845566 0.25265005857130607 0.16517765658690103 83.40316847685183 113425.95439131299 0.07391288887226294 0.050284248656706415 5.2949753873290186e-08 7.27613605428587 0.22006962221712334 STS(ph)PASEKADPGAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSPASEKADPGAVK 15 1 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;A0A087WYS3;Q9ULU4-4;Q9ULU4-18;Q9ULU4-8;Q9ULU4-15;Q9ULU4-17;A0A087WV57;Q9ULU4-2 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 S(0.02)T(0.158)S(0.821)PAS(0.002)EKADPGAVK 65.105 0.016319 9312400.0 39088.0 22105.0 20987.0 59757.0 51653.0 65043.0 49577.0 48638.0 62276.0 43498.0 True False 45704.826376809295 24299.438313144372 21487.409673640715 56409.009024807965 41531.965444163034 61632.03057834254 44880.70765360281 47361.30403622079 63186.668685383 51383.84307002144 0.8894785529086785 0.4729003683128801 0.4181744375242533 1.0977966157170975 0.8082689608787509 1.1994437725172826 0.8734400732238591 0.9217158781152457 1.229699160478863 1.0 15.649027175018242 -5.767490959121542 24.999994179577424 1.0080817836248646 0.5814560258693244 0.5637904258606181 0.17108000248010807 99.26636451702913 410086.22128982155 0.046756984349193335 0.07140764995678735 1.708083277528698e-06 5.767490959121542 -0.4266257577555401 STS(ph)PIIGSPPVR ddPTM_PC-9_AZD4547_30min_R2 1 STSPIIGSPPVR 12 0 Q86TB9-4;Q86TB9;Q86TB9-2 Q86TB9-4 PATL1 Protein PAT1 homolog 1 1 S(0.064)T(0.064)S(0.872)PIIGSPPVR 169.65 0.0010218 58806000.0 145800.0 213120.0 218250.0 241190.0 219000.0 211150.0 169200.0 197920.0 167660.0 168800.0 True False 192161.3671716051 282006.87221125094 215355.8623979834 185587.3718483537 188595.63021516684 197946.75712077893 184258.47221616792 167336.01174914517 176522.16531532604 162890.363378721 1.1796975780871017 1.7312679913150135 1.3220908710067756 1.1393391726732296 1.1578071673686487 1.2152146573615998 1.131180926816192 1.027292273638607 1.083686976036213 1.0 17.313541730743673 -5.632623684200545 3.6241457867317313 1.1157281169875102 1.4699216796404315 0.5149493757466754 0.1377738098191536 0.16439290132679504 4.122267970759914 0.03658495563704533 0.06773789909364632 2.3301094210032273e-06 5.632623684200545 0.35419356265292135 STS(ph)PIIGSPPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STSPIIGSPPVR 12 0 Q86TB9-4;Q86TB9;Q86TB9-2 Q86TB9-4 PATL1 Protein PAT1 homolog 1 1 S(0.116)T(0.047)S(0.837)PIIGSPPVR;ST(0.079)S(0.921)PIIGSPPVR;S(0.222)T(0.222)S(0.555)PIIGSPPVR;S(0.001)T(0.225)S(0.775)PIIGSPPVR 165.35 0.00034189 147940000.0 509420.0 695120.0 615120.0 543900.0 505680.0 267716.0 383683.0 240551.0 264454.0 220871.0 True False 595654.7444963705 764126.919711961 629786.7936555898 513427.0463475921 406595.6340542525 253676.50167291687 347337.76861563383 234236.79113485213 268321.1394521855 260913.16388612599 2.2829616398977115 2.9286637298433114 2.413779298350989 1.9678081347082752 1.5583561519023579 0.972264096968417 1.3312389587488478 0.8977576587016645 1.0283924944825424 1.0 17.993210208910824 -6.1733291666409436 1.2874235248934531 1.0345875048740711 2.6399559407643958 0.9188376986984423 0.19453353004900478 0.10781728910480608 0.36290450366259064 0.07236001020136208 0.11270610056866878 6.709201468423076e-07 6.1733291666409436 1.6053684358903246 up STS(ph)PIIGSPPVR ddPTM_PC-9_Lapatinib_30min_R1 1 STSPIIGSPPVR 12 0 Q86TB9-4;Q86TB9;Q86TB9-2 Q86TB9-4 PATL1 Protein PAT1 homolog 1 1 S(0.392)T(0.137)S(0.47)PIIGSPPVR 143.55 8.5614e-05 12296000.0 69785.0 97493.0 93933.0 68880.0 66351.0 66534.0 58673.0 60925.0 51831.0 47904.0 True False 68789.8531029984 97267.26094845214 86210.1913318656 73945.66497694427 62448.36463108499 63688.495918329325 61710.80085080614 63755.79791764738 45993.2469753734 56184.14257193229 1.2243642058776119 1.7312226634752206 1.5344221231371664 1.3161305235239995 1.111494485319103 1.1335671063554855 1.0983668705417742 1.1347649888226228 0.8186161587584694 1.0 15.77787538079641 -6.1182192866447185 1.94524593267976 1.0513138749236168 1.5217530163711595 0.6648959345676764 0.14406374570260266 0.19784764647251055 1.480161110466047 0.04720201742629848 0.06876575927931987 7.616943135276924e-07 6.1182192866447185 0.4704391414475426 STS(ph)PSAAGGQQK ddPTM_PC-9_AZD4547_30min_R2 1 STSPSAAGGQQK 12 0 Q2TB10 Q2TB10 ZNF800 Zinc finger protein 800 1 S(0.003)T(0.091)S(0.906)PS(0.001)AAGGQQK 142.12 6.7278e-05 0.0 28880.0 32571.0 28068.0 35312.0 36436.0 37147.0 30052.0 42874.0 33414.0 35203.0 True False 38063.239258682835 43098.93878938 27695.799980694603 27171.363964961518 31377.490331140736 34824.19221769162 32726.569781561884 36248.80844650796 35180.19582396699 33970.55368495926 1.120477446781671 1.2687146400107812 0.8152884476815915 0.7998504886598848 0.9236673214729901 1.0251287789021324 0.9633805231750414 1.067065576342296 1.0356085493991611 1.0 15.051997112398153 -5.252176943234276 24.998315181011634 0.9524664896966543 1.1945960556833068 0.5320153654704827 0.0903492804266538 552.8567426512916 1492093.4522446927 0.025574086469290516 0.06566737707087907 5.595295876694142e-06 5.252176943234276 0.24212956598665258 STS(ph)PSAAGGQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSPSAAGGQQK 12 0 Q2TB10 Q2TB10 ZNF800 Zinc finger protein 800 1 S(0.19)T(0.062)S(0.748)PSAAGGQQK 141.37 7.823199999999999e-05 4432300.0 26950.0 42019.0 35045.0 31903.0 48912.0 30968.0 34508.0 29416.0 33548.0 26043.0 True False 31512.102713237076 46190.36862610325 35880.60570890263 30115.57834092151 39328.04471772988 29343.98356395171 31239.152423715164 28643.861168828294 34038.57603341946 30764.389743725416 1.0243044954163005 1.5014232042592053 1.1663031839017934 0.9789103112979436 1.2783625823668767 0.9538295350043988 1.0154322151014414 0.9310719766404723 1.1064277990549716 1.0 14.908973754424366 -6.074627182746338 0.899156342052458 1.0044066541144563 1.264316861162029 0.24907470455073255 0.1462009125787491 0.8144260053544153 1.356501151513542 0.0669144604149019 0.13779831092528205 8.421177419053414e-07 6.074627182746338 0.2599102070475727 STS(ph)PSAAGGQQK ddPTM_PC-9_Lapatinib_30min_R1 1 STSPSAAGGQQK 12 0 Q2TB10 Q2TB10 ZNF800 Zinc finger protein 800 1 S(0.289)T(0.105)S(0.605)PS(0.001)AAGGQQK 151.16 0.00018407 8498900.0 34080.0 46635.0 40633.0 34037.0 46805.0 39396.0 41747.0 41550.0 43993.0 34842.0 True False 33594.01295049343 46527.01952274587 37292.31158791587 36540.19452410346 44052.02192217055 37711.12491656148 43908.455390360214 43480.56468573243 39038.04507317247 40864.393275953254 0.8220852007672387 1.138571156766074 0.91258693934557 0.8941817458869658 1.0780050403462875 0.9228357964818402 1.0744917976354305 1.0640208063805678 0.9553071009656834 1.0 15.318556694161838 -6.2608349978019415 24.99999616851451 1.0172664998055703 0.9538166614011074 0.13696047033586622 0.08885254408710488 133.1753552160582 5508786.3298467845 0.026131841780261258 0.031712228647690154 5.484853122425946e-07 6.2608349978019415 -0.06344983840446283 STS(ph)PTFNK ddPTM_PC-9_AZD4547_30min_R2 3 STSPTFNK 8 0 Q9BX63 Q9BX63 BRIP1 Fanconi anemia group J protein 1 S(0.378)T(0.054)S(0.562)PT(0.006)FNK;S(0.278)T(0.278)S(0.442)PT(0.001)FNK;S(0.003)T(0.003)S(0.77)PT(0.225)FNK 107.21 0.0038138000000000004 75728300.0 275521.0 256191.0 325063.0 418752.0 382292.0 334949.0 297731.0 377210.0 295026.0 311645.0 True False 363130.94680718693 338999.7306619401 320752.45222760923 322215.1960539074 329217.35464025836 314004.58608026523 324228.48221862747 318920.8619234792 310620.4720524834 300734.403407355 1.2074805632241339 1.1272396068458899 1.0665638802659339 1.0714277861234782 1.094711316398085 1.0441259214860605 1.0781223516334741 1.0604734886001386 1.032873088456519 1.0 18.19813039318371 -1.522878745280421 0.6269404670886396 1.0516208774301545 12.908999045342322 0.8116628833383304 0.02345778896194502 80.79728324333459 0.5683970403353916 0.00994516147696306 1322.2534099225052 0.02999999999999423 1.522878745280421 11.857378167912167 STS(ph)PTFNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STSPTFNK 8 0 Q9BX63 Q9BX63 BRIP1 Fanconi anemia group J protein 1 S(0.006)T(0.22)S(0.766)PT(0.008)FNK;S(0.079)T(0.079)S(0.833)PT(0.009)FNK;ST(0.003)S(0.987)PT(0.01)FNK;ST(0.013)S(0.971)PT(0.017)FNK 106.88 0.003819 62791200.0 519457.0 524463.0 578606.0 603338.0 657057.0 601730.0 632170.0 617076.0 590662.0 444810.0 True False 607390.810356585 576528.2205847827 592402.1614154733 569534.9279081888 528311.3975731401 570174.2195148757 572286.2810855464 600878.4088460677 599299.3143272803 525450.5318859762 1.1559428975673585 1.0972074164916639 1.127417569241372 1.0838982803271364 1.0054445956632596 1.0851149345465019 1.0891344595874033 1.143548959193859 1.1405437390580648 1.0 19.0031954236631 -4.242990753547896 1.0448417336514908 1.0850669852808172 1.2862146898607851 0.1827710357529363 0.04649646061520543 9.74282271079731 3.969705176524702 0.015373438258163058 2.863454327221557 5.7149080400604886e-05 4.242990753547896 0.2011477045799679 STS(ph)PTFNK ddPTM_PC-9_Lapatinib_30min_R1 2 STSPTFNK 8 0 Q9BX63 Q9BX63 BRIP1 Fanconi anemia group J protein 1 ST(0.007)S(0.832)PT(0.161)FNK;S(0.352)T(0.048)S(0.589)PT(0.011)FNK 108.43 0.0064351 0.0 125660.0 115699.0 130971.0 114328.0 123231.0 119028.0 110087.0 103943.0 129989.0 86312.0 True False 123868.06535677842 115431.10607402511 120203.06994268003 122736.0625070279 115982.7948614678 113937.44990782006 115786.76620017199 108772.57124257713 115348.26997514642 101230.914196489 1.223618954150219 1.1402752507991143 1.1874146440025832 1.2124365711920517 1.1457250562446313 1.1255203098004993 1.1437886056766227 1.0744995449853372 1.1394569622403652 1.0 16.62729040624049 -10.256485379887424 0.13332989001456655 0.825739059750968 1.2605311134292807 0.7668476362332578 0.030010941431302063 13.807073945769774 0.42385899650625963 1.1709165484720532 0.30944121061242275 5.540061937186987e-11 10.256485379887424 0.43479205367831275 STS(ph)PVTDPSIPIR ddPTM_PC-9_AZD4547_30min_R2 3 STSPVTDPSIPIR 13 0 A0A087WU18;Q99607 A0A087WU18 ELF4 ETS-related transcription factor Elf-4 1 S(0.09)T(0.257)S(0.642)PVT(0.01)DPSIPIR;S(0.002)T(0.022)S(0.973)PVT(0.003)DPSIPIR;S(0.032)T(0.045)S(0.815)PVT(0.108)DPSIPIR 181.76 7.8477e-05 111172900.0 139584.0 126528.0 191385.0 254507.0 207039.0 180362.0 150283.0 207742.0 152482.0 168095.0 True False 183968.80847243726 167425.70161010334 188847.10985126268 195834.34324395304 178295.2086032779 169083.9356278382 163657.89586325278 175640.24733625184 160541.88722182717 162210.0452141358 1.1341394315597249 1.0321537201292452 1.1642134098536432 1.2072886299083962 1.0991625602958672 1.0423764780080547 1.0089257767433923 1.0827951321040976 0.9897160623430782 1.0 17.30750363882479 -6.706054112716136 3.502999671874821 1.0276366788319589 1.1314101189321608 0.5468060242433929 0.047484972468852575 0.20622742877180125 5.144599803324803 0.017607693781428024 0.01698009732586352 1.9676411080553172e-07 6.706054112716136 0.10377344010020195 STS(ph)PVTDPSIPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STSPVTDPSIPIR 13 0 A0A087WU18;Q99607 A0A087WU18 ELF4 ETS-related transcription factor Elf-4 1 ST(0.001)S(0.679)PVT(0.319)DPS(0.001)IPIR;S(0.002)T(0.002)S(0.984)PVT(0.012)DPSIPIR;ST(0.001)S(0.819)PVT(0.18)DPSIPIR;S(0.007)T(0.054)S(0.543)PVT(0.396)DPSIPIR 186.51 3.9719000000000004e-05 95834000.0 165919.0 180153.0 191691.0 192995.0 226337.0 193439.0 204863.0 169854.0 189956.0 155367.0 True False 194005.80965037402 198037.39925030107 196261.64043216562 182182.11584823206 181987.88962374892 183294.71831010235 185456.89356032058 165395.51247518923 192733.74713855423 183533.80721550496 1.0570576211203033 1.0790240896477783 1.0693487124239496 0.9926351913700251 0.9915769327994116 0.9986973031888241 1.0104781041378252 0.9011719147796144 1.050126677273396 1.0 17.48568630867588 -5.768061929698299 6.406447053225897 0.9887671319103237 1.0699304034603891 0.4955963245348979 0.03520574789505335 0.11069642171025348 19.08548317839354 0.00943540732677351 0.015058922726414741 1.705839121729158e-06 5.768061929698299 0.08116327155006542 STS(ph)PVTDPSIPIR ddPTM_PC-9_Lapatinib_30min_R1 2 STSPVTDPSIPIR 13 0 A0A087WU18;Q99607 A0A087WU18 ELF4 ETS-related transcription factor Elf-4 1 S(0.26)T(0.26)S(0.479)PVT(0.002)DPSIPIR;S(0.029)T(0.131)S(0.807)PVT(0.032)DPSIPIR 193.0 1.924e-06 46760000.0 115452.0 104354.0 110194.0 90836.0 110076.0 111938.0 103017.0 93150.0 110231.0 81053.0 True False 113805.63330869639 104112.3747244907 101134.27468114108 97516.3824600129 103601.54609774251 107150.67268022284 108350.71619394784 97478.0890607939 97815.62399611008 95062.90305366617 1.1971613495166387 1.095194564652794 1.0638668863715157 1.025809009903281 1.0898209792652345 1.1271554858758386 1.1397791642527502 1.0254061882137586 1.0289568365158164 1.0 16.536594839228584 STS(ph)PVTDPSIPIRK ddPTM_PC-9_AZD4547_30min_R2 1 STSPVTDPSIPIRK 14 1 A0A087WU18;Q99607 A0A087WU18 ELF4 ETS-related transcription factor Elf-4 1 S(0.154)T(0.154)S(0.676)PVT(0.016)DPSIPIRK 75.911 0.0077587 12416000.0 62575.0 47998.0 67693.0 111920.0 82469.0 64474.0 55168.0 72953.0 57759.0 65601.0 True False 82472.54835914388 63512.41484795248 66795.34659017956 86118.57314676285 71019.60286855992 60442.43058775811 60077.84512542282 61679.790143165876 60812.022822664454 63304.32895739039 1.3027947648675884 1.0032870720531948 1.055146586185898 1.3603899538170374 1.1218759291542701 0.954791427114588 0.9490321770231656 0.9743376347087104 0.9606297677303635 1.0 15.950016538789404 -6.692586682044205 4.816197878944062 0.9647509213999156 1.1674839455347183 0.5126310046244513 0.09867205012589585 0.18508255434748094 8.162068209100607 0.03438701469795378 0.033822182353863486 2.0296133832466547e-07 6.692586682044205 0.20273302413480276 STS(ph)PVTDPSIPIRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSPVTDPSIPIRK 14 1 A0A087WU18;Q99607 A0A087WU18 ELF4 ETS-related transcription factor Elf-4 1 S(0.192)T(0.192)S(0.602)PVT(0.013)DPS(0.001)IPIRK 71.781 0.011141 10046000.0 60513.0 47480.0 56164.0 68944.0 70669.0 66516.0 60979.0 55306.0 59593.0 59441.0 True False 70756.6557137704 52193.5006156116 57503.162763156106 65081.29119946376 56821.91675166124 63027.78386527415 55202.6276702714 53854.27610155077 60464.434886120376 70217.18276530283 1.0076829192972712 0.743315219439458 0.8189329235175576 0.9268570545901064 0.8092309391219162 0.8976119716443358 0.7861697877396082 0.7669672006288802 0.8611059644506034 1.0 16.09953649351148 STS(ph)PVTDPSIPIRK ddPTM_PC-9_Lapatinib_30min_R1 1 STSPVTDPSIPIRK 14 1 A0A087WU18;Q99607 A0A087WU18 ELF4 ETS-related transcription factor Elf-4 1 S(0.151)T(0.151)S(0.697)PVT(0.001)DPSIPIRK 98.421 0.0011267000000000002 11968000.0 179350.0 155880.0 148370.0 144060.0 153510.0 160110.0 103100.0 138300.0 148500.0 122780.0 True False 176792.4361112382 155519.0694372389 136171.59132476267 154654.65297007197 144480.84361227215 153262.46853463954 108438.01352782574 144725.92288897204 131774.3662256747 144002.35940593388 1.2277051351142871 1.0799758426099126 0.9456205570972851 1.0739730488311647 1.0033227525459458 1.0643052597673208 0.7530294224009593 1.0050246640820548 0.9150847720085667 1.0 17.135732924127694 -1.5228787453389165 0.5313107991025096 0.9471157224362425 11.55351043794027 0.4730129966557248 0.085460115328002 111.25736673286056 1.0798019046118958 0.04425250154377239 1336.389647671961 0.029999999995953507 1.5228787453389165 10.606394715504027 STS(ph)QELAK ddPTM_PC-9_AZD4547_30min_R2 1 STSQELAK 8 0 E7EV90;Q5BKX6-2;Q5BKX6;Q5BKX6-3 E7EV90 SLC45A4 Solute carrier family 45 member 4 1 S(0.011)T(0.23)S(0.759)QELAK 72.096 0.033615 4056500.0 33519.0 50641.0 44638.0 60576.0 53950.0 43432.0 53979.0 61345.0 44043.0 44601.0 True False 44177.344761488566 67009.71291127046 44046.07095404891 46611.139089870565 46459.97374478652 40716.1901741401 58783.02642882097 51865.53981786238 46371.02306443344 43039.53256548786 1.0264364440824127 1.5569340305754988 1.023386368962756 1.0829843242128208 1.0794720800950661 0.9460184102182657 1.3657914694909432 1.2050674513935553 1.0774053596859228 1.0 15.393374789016603 STS(ph)QELAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 STSQELAK 8 0 E7EV90;Q5BKX6-2;Q5BKX6;Q5BKX6-3 E7EV90 SLC45A4 Solute carrier family 45 member 4 1 S(0.007)T(0.064)S(0.928)QELAK;S(0.002)T(0.052)S(0.946)QELAK;S(0.002)T(0.023)S(0.975)QELAK 82.749 0.016028 14065500.0 143773.0 147644.0 143810.0 133958.0 259321.0 124229.0 124769.0 127638.0 133182.0 117218.0 True False 168110.9292538116 162301.12057479666 147238.97580246182 126452.76755769552 208508.91160137454 117714.21254734432 112949.9770706654 124287.63774363996 135129.53479441 138468.69550282246 1.2140717339998695 1.1721141734269347 1.063337639368897 0.9132227836660597 1.5058198594578687 0.850114259543558 0.8157076706797104 0.8975865432422345 0.975885085821839 1.0 17.079200328346104 STS(ph)QELAK ddPTM_PC-9_Lapatinib_30min_R1 3 STSQELAK 8 0 E7EV90;Q5BKX6-2;Q5BKX6;Q5BKX6-3 E7EV90 SLC45A4 Solute carrier family 45 member 4 1 S(0.007)T(0.028)S(0.966)QELAK;S(0.004)T(0.021)S(0.975)QELAK;S(0.044)T(0.005)S(0.951)QELAK 91.54899999999999 0.0086414 15297600.0 347460.0 346810.0 181221.0 136767.0 161384.0 135668.0 96993.0 102714.0 205297.0 83976.0 True False 342505.15668363945 346006.9827529434 166321.70891328948 146825.3014213371 151891.71041315174 129865.79589755459 102014.82294960614 107486.46741589232 182174.28998674973 98491.13970901362 3.4775225233005846 3.5130772552252014 1.6886971701685791 1.4907462930688382 1.5421865445146337 1.3185530828583727 1.035776652102951 1.0913313393819473 1.849651557743906 1.0 16.587706324699 -5.3114562441177595 3.321505266648333 1.3429768381109404 3.5559452215657648 0.9216817527069547 0.2484830483033382 0.058743402377279506 1.2985208479614312 0.06883975200810112 0.177767001980613 4.881392796041659e-06 5.3114562441177595 2.2129683834548244 STS(ph)QGSINSPVYSR ddPTM_PC-9_AZD4547_30min_R2 1 STSQGSINSPVYSR 14 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4;H0Y7N6;F6XFR5 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 ST(0.002)S(0.998)QGSINSPVYSR 186.29 5.2015e-06 36456000.0 34715.0 42056.0 51120.0 77343.0 67069.0 56490.0 59248.0 88191.0 61834.0 63637.0 True False 45753.64788314317 55649.77955009563 50442.115398785376 59512.766287438295 57757.6270452102 52957.671369892596 64520.95722141548 74563.10737757108 65102.41900338704 61409.087999595286 0.7450631392448738 0.906214069657937 0.8214112445232505 0.9691198522249754 0.9405387529218942 0.8623751482881754 1.0506744086777628 1.2142031384355112 1.0601430687883868 1.0 15.906164556997158 -7.358094150410108 4.1208665550146835 1.1073250192193898 0.8803829542647646 0.6301636275118521 0.07756330298389351 0.14582514333712104 4.38985147427591 0.03373716195910215 0.022131860188513215 4.384356393026774e-08 7.358094150410108 -0.2269420649546251 STS(ph)QGSINSPVYSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 STSQGSINSPVYSR 14 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4;H0Y7N6;F6XFR5 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 STS(1)QGSINSPVYSR;S(0.01)T(0.003)S(0.985)QGS(0.002)INSPVYSR;ST(0.032)S(0.967)QGSINSPVYSR 181.58 2.958e-05 40103300.0 95304.0 93856.0 97338.0 125393.0 141639.0 123133.0 112642.0 148388.0 114485.0 99304.0 True False 111437.0848601982 103173.4034073051 99658.90707642067 118367.63673959085 113885.85471406882 116675.68871674186 101971.73430254191 144492.97223008185 116159.12654065902 117307.02910996861 0.9499608480897792 0.8795159521991299 0.8495561419682376 1.0090412964821398 0.9708357255157094 0.994618051467019 0.8692721576551842 1.2317503335169113 0.9902145457265523 1.0 16.839929937575306 -6.783966769694348 0.7029822481066379 1.0565180150060351 0.8991901634230999 0.23456295448365816 0.08964733497024004 0.9652477695946862 1.0440890966473249 0.06651568271210924 0.06621053412960072 1.644497548128254e-07 6.783966769694348 -0.15732785158293527 STS(ph)QGSINSPVYSR ddPTM_PC-9_Lapatinib_30min_R1 3 STSQGSINSPVYSR 14 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4;H0Y7N6;F6XFR5 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 S(0.033)T(0.004)S(0.964)QGSINSPVYSR;S(0.004)T(0.007)S(0.989)QGSINSPVYSR;S(0.041)T(0.071)S(0.887)QGS(0.001)INSPVYSR 244.57 6.0318e-35 67228800.0 219271.0 186786.0 198114.0 183963.0 225991.0 195988.0 228540.0 187805.0 224669.0 223067.0 True False 216144.15533062373 186353.50849309773 181825.8316621556 197492.25270257788 212698.65369540072 187606.05011034218 240372.6829451918 196531.10591585972 199364.41135054626 261623.83373190585 0.8261638561267832 0.7122956109727374 0.6949895545391259 0.7548710294680354 0.8129941781732306 0.7170831779133242 0.9187721145907113 0.7511972556646017 0.7620269472652145 1.0 17.997134449678633 -14.522878745253685 0.2156502503303619 2.131236985620666 0.740950954576171 0.5475520706503132 0.0624395122932714 114.07950057754583 1.1369861131581973 55.946728109877036 0.12513141513291853 3.0000000001841097e-15 14.522878745253685 -1.3902860310444949 STS(ph)SHGTDEMESSSYR ddPTM_PC-9_AZD4547_30min_R2 2 STSSHGTDEMESSSYR 16 0 Q8IWS0-5;Q8IWS0;Q8IWS0-3;Q8IWS0-4;A0A0D9SGE8;Q5JRC6;Q8IWS0-2 Q8IWS0-5;A0A0D9SGE8 PHF6 PHD finger protein 6 1 S(0.002)T(0.011)S(0.493)S(0.493)HGTDEMESSSYR;S(0.006)T(0.006)S(0.977)S(0.011)HGTDEMESSSYR 117.0 0.0015604000000000002 0.0 2539.3 6556.0 16131.0 22344.0 16734.8 14330.8 10861.400000000001 18736.7 13219.9 13945.7 True False 3346.7445792788553 8675.098790432443 15917.092400191834 17192.936011358757 14411.461883674756 13434.692810544473 11828.043558680156 15841.373541533008 13918.676925039239 13457.465287740722 0.24869056005127665 0.6446309616964164 1.1827704593592185 1.27757609949185 1.0708897682837117 0.9983078182473936 0.8789206069478097 1.1771439273905422 1.0342718058294873 1.0 13.716119083616144 -5.000004355664939 2.9425467335885354 1.0795545011703935 0.25310700537783126 0.8527737246364693 0.11052662153052961 0.10560462219364522 1.7132551486030696 0.031734326819216584 0.16284049159286698 9.999899707611347e-06 5.000004355664939 -0.8264474957925623 down STS(ph)SHGTDEMESSSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSSHGTDEMESSSYR 16 0 Q8IWS0-5;Q8IWS0;Q8IWS0-3;Q8IWS0-4;A0A0D9SGE8;Q5JRC6;Q8IWS0-2 Q8IWS0-5;A0A0D9SGE8 PHF6 PHD finger protein 6 1 S(0.015)T(0.39)S(0.564)S(0.031)HGTDEMESSSYR 127.66 0.00013541 0.0 4525.9 6096.1 12667.0 11122.0 11503.0 10693.0 11044.0 7951.5 8594.0 6635.4 True False 5292.045479400353 6701.280520278638 12969.029319865018 10498.870398010511 9249.069724976422 10132.240256049332 9997.832368364143 7742.781550310662 8719.670991749335 7838.345494202496 0.6751482801204064 0.854935588796785 1.6545620921478068 1.3394242963359841 1.1799772964610127 1.2926503767336457 1.2755028948084612 0.9878081485483746 1.1124376946893573 1.0 12.93633344930767 -10.678993100506197 14.452232444451496 0.9999999885394467 1.1677117852852232 0.027366796091331858 0.2587963919272616 0.0 0.0 0.265886203076832 0.06448687645177682 2.094145724591993e-11 10.678993100506197 0.16771179674577652 STS(ph)SSSDTMSTFKPMVAPR ddPTM_PC-9_AZD4547_30min_R2 1 STSSSSDTMSTFKPMVAPR 19 1 G5EA48;Q7Z6B7-2;Q7Z6B7 G5EA48 SRGAP1 SLIT-ROBO Rho GTPase-activating protein 1 1 S(0.006)T(0.025)S(0.379)S(0.085)S(0.085)S(0.378)DT(0.036)MS(0.004)T(0.001)FKPMVAPR 60.541000000000004 0.029681 5247400.0 16681.0 23162.0 22610.0 32602.0 22026.0 22564.0 20307.0 31183.0 18849.0 22757.0 True False 21985.211013645698 30648.663542403327 22310.176626888446 25086.11259587889 18968.07009643499 21153.0695130157 22114.28366012834 26364.38386405418 19845.31965900384 21960.284356691718 1.0011350789702496 1.3956405593201753 1.015932957174578 1.1423400621055562 0.8637442843792256 0.9632420586835414 1.0070126279302798 1.200548382517663 0.9036913792492214 1.0 14.422609115009726 -5.407665257230718 24.83982929121683 1.0166401494109958 1.2002475963733812 0.2492254106703573 0.12915236774375516 24.7586485449471 5300.413058601596 0.03243025364454739 0.06750895303074196 3.911422618074619e-06 5.407665257230718 0.1836074469623854 STS(ph)TPNVHMVSTTLPVDSR ddPTM_PC-9_AZD4547_30min_R2 7 STSTPNVHMVSTTLPVDSR 19 0 P04049;P04049-2;H7C155 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 S(0.251)T(0.251)S(0.396)T(0.102)PNVHMVSTTLPVDSR;S(0.15)T(0.15)S(0.521)T(0.178)PNVHMVSTTLPVDSR;S(0.159)T(0.159)S(0.644)T(0.039)PNVHMVSTTLPVDSR;S(0.123)T(0.123)S(0.376)T(0.376)PNVHMVSTTLPVDSR;S(0.147)T(0.147)S(0.59)T(0.116)PNVHMVSTTLPVDSR;STS(0.907)T(0.093)PNVHMVSTTLPVDSR;S(0.117)T(0.117)S(0.76)T(0.005)PNVHMVSTTLPVDSR 280.63 2.0467999999999996e-92 381382200.0 93707.59999999999 71158.4 130089.0 211667.0 158111.0 146392.0 111846.8 155790.0 103213.40000000001 136913.2 True False 123504.6675608363 94158.96122164547 128363.93486135747 162870.4433725508 136160.01684452192 137238.0850979165 121800.94852403822 131716.2351980563 108669.04960966768 132119.910541135 0.9347922433113033 0.7126780576522526 0.9715714636469714 1.2327471514737496 1.030579087488324 1.0387388587822877 0.9218969951248641 0.9969446290008422 0.8225032030719852 1.0 17.011488372319235 -5.4537607844391145 8.50891879124556 1.0122805123515506 0.8271401296309192 0.3023034521592687 0.10904891016278966 0.4291879555303279 49.27392704741425 0.029370369117798806 0.06116946201155272 3.5175413834650834e-06 5.4537607844391145 -0.18514038272063138 STS(ph)TPNVHMVSTTLPVDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STSTPNVHMVSTTLPVDSR 19 0 P04049;P04049-2;H7C155 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 S(0.023)T(0.023)S(0.719)T(0.22)PNVHMVS(0.014)TTLPVDSR;S(0.119)T(0.119)S(0.627)T(0.134)PNVHMVSTTLPVDSR;S(0.002)T(0.003)S(0.498)T(0.498)PNVHMVSTTLPVDSR;S(0.259)T(0.269)S(0.319)T(0.153)PNVHMVSTTLPVDSR 181.86 1.9099e-09 81012200.0 57111.8 59868.8 83530.0 83574.0 108973.0 109841.0 86572.0 79923.0 92627.0 69456.6 True False 66779.69973053249 65812.17880488475 85521.6719892891 78891.61973056372 87620.52291922571 104080.74459597071 78371.27343299724 77825.10593541835 93981.49464193246 82048.53176185698 0.8139048718672779 0.8021128153262062 1.0423303153981205 0.961523844930509 1.0679109185468576 1.2685265946996036 0.9551819118526965 0.94852527235104 1.145437860054711 1.0 16.32418989684919 -5.267277061707273 7.973025719996087 1.0490996200337133 0.8074817224256267 0.5160487591567667 0.09322675986195599 0.09451106164347182 60.201223465388765 0.02521331358107167 0.05770994979423447 5.4040945433189035e-06 5.267277061707273 -0.2416178976080866 STS(ph)TPNVHMVSTTLPVDSR ddPTM_PC-9_Lapatinib_30min_R1 5 STSTPNVHMVSTTLPVDSR 19 0 P04049;P04049-2;H7C155 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 S(0.129)T(0.129)S(0.577)T(0.166)PNVHMVSTTLPVDSR;S(0.016)T(0.016)S(0.756)T(0.107)PNVHMVS(0.104)T(0.001)TLPVDSR;S(0.152)T(0.152)S(0.52)T(0.176)PNVHMVSTTLPVDSR;S(0.022)T(0.022)S(0.956)TPNVHMVSTTLPVDSR;STS(0.92)T(0.08)PNVHMVSTTLPVDSR 342.98 1.0368999999999995e-222 170122700.0 184958.0 132195.0 173060.0 128687.0 165387.1 157501.0 132315.0 141989.0 175340.0 119506.4 True False 182320.46500285703 131888.91059953682 158831.67483091872 138151.07126724784 155659.35594154906 150765.04938276327 139165.6232777329 148586.327296329 155591.36278794496 140162.92200773148 1.3007752862971858 0.9409686150254611 1.1331932336724362 0.9856463413314638 1.1105601517993666 1.075641455123538 0.9928847179003334 1.0600972437499045 1.1100750509422346 1.0 17.096745230987693 -4.745369368400613 24.999874056203296 1.0495382431603226 1.3007759940723607 0.6144982428798937 0.060590946741097634 600.3119516564516 933845.67160712 0.01395458176672347 0.3574183880679451 1.7973416219321675e-05 4.745369368400613 0.25123775091203804 STS(ph)TPTSPGPR ddPTM_PC-9_AZD4547_30min_R2 4 STSTPTSPGPR 11 0 H3BUF6;H3BRB0;A0A0C4DGL7;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 S(0.023)T(0.004)S(0.952)T(0.006)PT(0.015)S(0.001)PGPR;S(0.022)T(0.002)S(0.768)T(0.17)PT(0.038)SPGPR;S(0.003)T(0.097)S(0.891)T(0.007)PT(0.001)S(0.001)PGPR;S(0.003)T(0.208)S(0.784)T(0.001)PT(0.003)SPGPR 156.58 0.00061307 76645200.0 114249.0 132963.0 214296.0 279453.0 241806.0 216516.0 178275.0 234125.0 153590.0 193716.0 True False 150577.80547317376 175940.68951681975 211454.29502148126 215029.4283558109 208235.410775382 202977.2202925061 194141.1296355635 197946.36090727887 161708.45383980038 186934.0618025616 0.8055129387399336 0.9411911762910659 1.1311704939296603 1.1502955977221714 1.113951137462143 1.0858225533390975 1.0385540642700737 1.0589100723459826 0.8650561180797306 1.0 17.512169945158853 -4.96417715133369 3.400168025132291 1.0631189211323593 0.8100741863385337 0.5045170612528158 0.07741921631489015 0.20319564041318547 4.626126251314326 0.02082173343779139 0.1058855950407741 1.0859825544361743e-05 4.96417715133369 -0.2530447347938256 STS(ph)TPTSPGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSTPTSPGPR 11 0 H3BUF6;H3BRB0;A0A0C4DGL7;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 S(0.001)T(0.003)S(0.956)T(0.039)PT(0.001)SPGPR 123.01 0.00061307 12630000.0 13740.0 14551.0 26709.0 25634.0 28916.0 26043.0 25634.0 23767.0 26921.0 15343.0 True False 16065.91062262996 15995.527115791154 27345.84385444656 24197.810086549296 23250.117375242826 24677.25923391869 23205.76194591149 23143.14143321805 27314.668695471704 18124.56444487882 0.8864163699762428 0.8825330486940758 1.5087724694081273 1.3350836738803122 1.2827959229559447 1.3615366763139716 1.2803486680458347 1.2768936601815695 1.5070524193032178 1.0 14.145658705393513 -5.2464025316636596 24.613639485527635 1.3283610344729877 0.884474578555218 0.6255335279908246 0.13434415019634263 376.62603368185125 616491.4939362995 0.03169474362561106 0.08309923933930148 5.670188127878838e-06 5.2464025316636596 -0.44388645591776965 STS(ph)TPTSPGPR ddPTM_PC-9_Lapatinib_30min_R1 1 STSTPTSPGPR 11 0 H3BUF6;H3BRB0;A0A0C4DGL7;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 S(0.318)T(0.004)S(0.663)T(0.014)PT(0.001)SPGPR 111.5 0.0018047999999999999 9046900.0 26817.0 23141.0 26793.0 21746.0 21140.0 23796.0 13504.0 18832.0 25057.0 17291.0 True False 26434.584662364483 23087.41843627881 24590.182963970892 23345.27338252944 19896.58676283912 22778.300551185323 14203.171044420542 19707.003469596002 22234.816798092488 20279.726311190756 1.3034980973967758 1.138448225681365 1.2125500406976173 1.1511631382148908 0.9811072623726578 1.123205520708423 0.7003630535478652 0.9717588475896386 1.0964061574057276 1.0 14.307750561863473 -6.239403867993425 1.3023969256896637 0.9530932045302525 1.2229663034211977 0.48939418114927513 0.11268452144019625 0.3826721118912467 1.317854440453874 0.044795105135730144 0.06516771347062189 5.762303542577633e-07 6.239403867993425 0.26987309889094524 STS(ph)VPENPK ddPTM_PC-9_AZD4547_30min_R2 4 STSVPENPK 9 0 A0A494C0P1;P04150-7;P04150-5;P04150-2;P04150-6;P04150-10;P04150;P04150-3;D6RDA9;Q3MSN4;P04150-9;P04150-8;P04150-13;P04150-12;P04150-11 A0A494C0P1 NR3C1 Glucocorticoid receptor 1 S(0.222)T(0.222)S(0.557)VPENPK;ST(0.004)S(0.996)VPENPK;S(0.02)T(0.005)S(0.975)VPENPK;S(0.006)T(0.006)S(0.989)VPENPK 154.84 6.9578e-05 125714000.0 974455.0 881490.0 1091560.0 1814640.0 1219520.0 1041180.0 1495970.0 2401120.0 1924250.0 1478130.0 True False 1284311.4200768645 1166414.4040235346 1077085.2011873657 1396302.7839085227 1050210.6984474887 976074.8500071642 1629108.4319221072 2030082.0762485194 2025961.9265657684 1426381.1186077558 0.9003985003183715 0.817743861585909 0.7551173996460873 0.9789128345104627 0.7362763603268706 0.6843015777998233 1.1421270308963618 1.423239588469887 1.4203510549433267 1.0 20.443928080182076 -7.449830195619542 4.382096618804404 1.3132939416594136 0.8158307269733709 0.7144067737852016 0.13591123612514522 0.10960335299501794 3.9697292962852053 0.05948168433131355 0.03799962358542965 3.549521445024229e-08 7.449830195619542 -0.4974632146860427 STS(ph)VPENPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STSVPENPK 9 0 A0A494C0P1;P04150-7;P04150-5;P04150-2;P04150-6;P04150-10;P04150;P04150-3;D6RDA9;Q3MSN4;P04150-9;P04150-8;P04150-13;P04150-12;P04150-11 A0A494C0P1 NR3C1 Glucocorticoid receptor 1 S(0.086)T(0.013)S(0.9)VPENPK;STS(1)VPENPK;ST(0.019)S(0.981)VPENPK;S(0.001)T(0.001)S(0.997)VPENPK 161.51 6.9578e-05 91995000.0 1025620.0 950440.0 618160.0 744950.0 1140910.0 1154190.0 1282340.0 2040360.0 1372080.0 1109820.0 True False 1199237.2090816419 1044793.4019608672 632899.2787848554 703212.8666604876 917356.8755909653 1093662.2445646299 1160867.4718623743 1986802.7119401186 1392144.0742796622 1311021.5806697118 0.914734911128643 0.7969307426862899 0.4827527541244212 0.5363854241829215 0.6997267544004501 0.8342061341247733 0.8854678587894533 1.515461485329018 1.0618773136964765 1.0 20.322260003220165 -7.455699475957174 2.791515705435412 1.2153013038579592 0.6927642448989351 0.5754916177728555 0.18072241178671125 0.1848635408825316 2.8296786988495786 0.09246278021561312 0.05428339262750621 3.501874066513871e-08 7.455699475957174 -0.5225370589590241 STS(ph)VPENPK ddPTM_PC-9_Lapatinib_30min_R1 3 STSVPENPK 9 0 A0A494C0P1;P04150-7;P04150-5;P04150-2;P04150-6;P04150-10;P04150;P04150-3;D6RDA9;Q3MSN4;P04150-9;P04150-8;P04150-13;P04150-12;P04150-11 A0A494C0P1 NR3C1 Glucocorticoid receptor 1 S(0.007)T(0.025)S(0.968)VPENPK;ST(0.007)S(0.993)VPENPK;ST(0.001)S(0.999)VPENPK 143.4 0.00060673 71550000.0 375213.0 317629.0 270449.0 241051.0 477764.0 364177.0 574940.0 420512.0 472892.0 551740.0 True False 369862.39381436346 316893.54956556775 248213.72718333005 258778.6946625633 449662.86084016383 348601.99864805053 604707.579996975 440050.5226745292 419629.9231864771 647107.5238526632 0.5715624995554458 0.48970771917298817 0.38357416354170626 0.39990061175904884 0.6948812125734848 0.5387079979731808 0.9344777455170773 0.680026898860045 0.648470165650586 1.0 19.303645925820796 -6.761069209311347 1.4205900819273305 0.7839226225650224 0.4640120390753721 0.553524712843847 0.13052639148988843 0.3255658048653535 1.3712443853918053 0.0595047694689059 0.05383833778716062 1.7335277201937474e-07 6.761069209311347 -0.31991058348965035 STS(ph)WHTALR ddPTM_PC-9_AZD4547_30min_R2 2 STSWHTALR 9 0 E7EPJ7;O75962-4;O75962;O75962-2;O75962-3 E7EPJ7 TRIO Triple functional domain protein 1 S(0.011)T(0.014)S(0.971)WHT(0.005)ALR;S(0.036)T(0.007)S(0.956)WHTALR 91.469 0.0044074 22609000.0 79559.0 76518.0 104029.0 160176.0 114837.0 99540.0 77324.0 118609.0 78747.0 90765.0 True False 104857.10706999809 101250.94710895506 102649.5074886588 123249.89789453088 98893.86478090902 93315.74806442042 84205.68620356366 100280.7044136742 82909.40565481332 87587.34497671576 1.1971718870788164 1.1559997295941742 1.1719673374726356 1.407165589130435 1.1290885093868182 1.065402177554617 0.9613910117488882 1.1449222994524249 0.9465911505463943 1.0 16.4184348172044 -6.632037951800178 3.4477930575360296 1.0277961212255073 1.227067321469963 0.5794735699318148 0.08347201754138384 0.1838536651364724 4.276473189050028 0.02904015400659829 0.02896864097518905 2.3332541567089893e-07 6.632037951800178 0.19927120024445566 STS(ph)WHTALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSWHTALR 9 0 E7EPJ7;O75962-4;O75962;O75962-2;O75962-3 E7EPJ7 TRIO Triple functional domain protein 1 S(0.001)T(0.063)S(0.916)WHT(0.02)ALR 72.289 0.018525 6613400.0 30399.0 39187.0 39740.0 37730.0 48345.0 38878.0 44533.0 33924.0 35355.0 31106.0 True False 35544.95029238197 43077.22638213925 40687.55231478929 35616.1104223104 38872.14429748634 36839.16923919253 40314.5118490004 33033.53094544912 35871.99998991131 36745.27156503948 0.9673339936940476 1.1723202618299375 1.107286749609999 0.9692705729298949 1.057881535279506 1.0025553675385648 1.0971346824214738 0.898987258455267 0.9762344503677848 1.0 15.165270993347095 -7.04708554122833 0.6805999734123231 0.9651748625855461 1.0752038451483334 0.18150680484005155 0.070413846597078 1.133712217063478 1.0934223679145292 0.058053144795157524 0.04602315745878632 8.972520489862272e-08 7.04708554122833 0.11002898256278737 STS(ph)WHTALR ddPTM_PC-9_Lapatinib_30min_R1 2 STSWHTALR 9 0 E7EPJ7;O75962-4;O75962;O75962-2;O75962-3 E7EPJ7 TRIO Triple functional domain protein 1 S(0.008)T(0.01)S(0.965)WHT(0.017)ALR;ST(0.008)S(0.977)WHT(0.015)ALR 81.525 0.0096939 15241000.0 70815.0 54987.0 70474.0 52943.0 76656.0 83653.0 74224.0 80638.0 97130.0 72577.0 True False 69805.16511411953 54859.680979891215 64679.899757506915 56836.60483267063 72147.24479149457 80075.35619466733 78066.95553917877 84384.73586349223 86190.19657575627 85121.83774722644 0.8200617721789497 0.6444842173497215 0.7598508381548001 0.6677088551759159 0.8475762119438659 0.9407146076011083 0.917120184493696 0.9913406253525321 1.01255093706626 1.0 16.37724167794717 -6.602786682779259 2.075747416074312 0.9754999106099954 0.7190185577203453 0.8338044518079575 0.05238241150593401 0.1190549945612295 1.0446504486057027 0.018988587729519925 0.01943214700801109 2.4958203255774113e-07 6.602786682779259 -0.2564813528896501 STSAPQMS(ph)PGSSDNQSSS(ph)PQPAQQK ddPTM_PC-9_AZD4547_30min_R2 1 STSAPQMSPGSSDNQSSSPQPAQQK 25 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 2 STSAPQMS(0.767)PGS(0.21)S(0.021)DNQS(0.044)S(0.343)S(0.612)PQPAQQK 138.24 2.7128e-07 2908400.0 32810.0 29757.0 38529.0 53793.0 46718.0 48141.0 33635.0 47104.0 40932.0 44440.0 True False 43242.89750960469 39375.36832014923 38018.08028559864 41391.854943565246 40232.012111379714 45130.735659727405 36628.449840371155 39825.15914223797 43095.581955665824 42884.16912648324 1.0083650538282183 0.9181795782032037 0.8865294830236192 0.9652012802552723 0.9381553363601096 1.0523868499496425 0.8541252071909947 0.928668083198185 1.0049298571824732 1.0 15.388157548538219 STSAPQMS(ph)PGSSDNQSSS(ph)PQPAQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSAPQMSPGSSDNQSSSPQPAQQK 25 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 2 STS(0.001)APQMS(0.913)PGS(0.02)S(0.066)DNQS(0.009)S(0.32)S(0.671)PQPAQQK 101.22 1.8047999999999999e-06 5695700.0 23356.0 22902.0 30406.0 31005.0 36277.0 29823.0 31464.0 34677.0 30161.0 22768.0 True False 27309.70949797271 25175.559205954865 31130.994355397146 29267.89036956623 29168.78226662346 28259.029379609015 28483.50214036669 33766.765493318584 30602.04756599394 26895.658168611168 1.0153947275343038 0.9360454779774172 1.1574728590107108 1.0882013069203713 1.0845163960577535 1.05069112651755 1.0590371859205376 1.2554727339867224 1.1378062352721432 1.0 14.71508567336528 -5.258997308246675 24.998182545914776 1.1084825820742112 0.9757200971590555 0.3604780712743584 0.06822980690531383 221.20101895439544 2264280.021518118 0.01807182281070548 0.043502381696533365 5.508111103171721e-06 5.258997308246675 -0.13276248491515574 STSAPQMS(ph)PGSSDNQSSSPQPAQQK ddPTM_PC-9_AZD4547_30min_R2 2 STSAPQMSPGSSDNQSSSPQPAQQK 25 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 STSAPQMS(0.659)PGS(0.232)S(0.109)DNQSSSPQPAQQK;STS(0.001)APQMS(0.455)PGS(0.375)S(0.131)DNQS(0.015)S(0.018)S(0.003)PQPAQQK 152.38 2.5081e-07 27286000.0 79664.0 66017.0 101849.0 138094.0 123462.0 107162.0 90365.0 112475.0 93549.0 100242.0 True False 104995.4948858625 87355.70421720242 100498.4157130455 106258.56183103177 106321.43240924602 100461.1431995122 98407.30993979896 95094.57316837652 98493.80915593126 96732.55809129 1.0854204309036721 0.9030641382890101 1.0389306113273828 1.098477740356579 1.0991276826247751 1.0385452962455866 1.0173132178198827 0.9830668706045419 1.0182074277719306 1.0 16.561713931001087 -10.079846857666157 9.865537123435566 0.9999997577466312 1.0301466413685816 0.02708635438626339 0.055950084422416294 0.0 0.0 0.05704775345929348 0.013836112542168374 8.320571220691867e-11 10.079846857666157 0.030146883621950393 STSAPQMS(ph)PGSSDNQSSSPQPAQQK ddPTM_PC-9_Lapatinib_30min_R1 2 STSAPQMSPGSSDNQSSSPQPAQQK 25 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 STSAPQMS(0.894)PGS(0.081)S(0.026)DNQSSSPQPAQQK;STS(0.001)APQMS(0.864)PGS(0.126)S(0.009)DNQSSSPQPAQQK 159.89 4.0587000000000005e-09 36518800.0 210032.0 168056.0 225346.0 170105.0 199273.0 191861.0 168645.0 167210.0 207927.0 153686.0 True False 207036.90516484858 167666.87665733026 206818.92174071542 182615.08915364507 187552.1539257919 183655.5522798355 177376.61291367756 174979.18703011636 184508.0716916222 180250.42032627692 1.1486070589465733 0.9301885474321292 1.1473977223817067 1.013118797854051 1.0405088298063212 1.0188911179646343 0.9840565841266978 0.9707560554554107 1.0236207569315976 1.0 17.459643098129973 -6.685893897653348 1.3597896706679675 0.9924604158977874 1.0581329329865765 0.1964769510725659 0.06002504479124346 0.7200932322399834 2.7854095056505344 0.02574550615730161 0.024865094910588758 2.0611334066099235e-07 6.685893897653348 0.06567251708878907 STSAPQMSPGS(ph)SDNQSSSPQPAQQK ddPTM_PC-9_AZD4547_30min_R2 5 STSAPQMSPGSSDNQSSSPQPAQQK 25 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 STSAPQMS(0.053)PGS(0.755)S(0.192)DNQSSSPQPAQQK;S(0.001)TSAPQMS(0.089)PGS(0.7)S(0.209)DNQS(0.001)SSPQPAQQK;STSAPQMSPGS(0.398)S(0.398)DNQS(0.028)S(0.131)S(0.044)PQPAQQK;STSAPQMS(0.22)PGS(0.609)S(0.171)DNQSSSPQPAQQK;S(0.001)T(0.001)SAPQMS(0.124)PGS(0.465)S(0.409)DNQSSSPQPAQQK 163.14 2.3847e-09 100805500.0 244320.0 202600.0 332518.0 459437.0 404187.0 345225.0 284084.7 382075.0 283983.0 339677.0 True False 322008.6778283027 268086.48794106394 328108.59405659855 353520.89788089064 348072.61182546866 323638.0261758045 309367.6879550134 323034.0879600587 298993.76161721465 327785.01161963266 0.9823776756515247 0.8178729302368349 1.000987178868756 1.0785145304054424 1.0618930075710054 0.987348459213137 0.9438127949364841 0.9855059765054571 0.9121642266064689 1.0 18.32239036134397 -5.301841301060436 24.32032643903846 0.9988483594553357 0.9001252844629563 0.2980670351953856 0.05891642772882686 399.10285973601435 240243.1016381134 0.01605570026522213 0.03342338340805703 4.99066822050242e-06 5.301841301060436 -0.09872307499237942 STSAPQMSPGS(ph)SDNQSSSPQPAQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STSAPQMSPGSSDNQSSSPQPAQQK 25 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 STSAPQMS(0.325)PGS(0.666)S(0.009)DNQSSSPQPAQQK;STSAPQMS(0.103)PGS(0.42)S(0.42)DNQS(0.039)S(0.011)S(0.006)PQPAQQK 131.62 1.8149999999999998e-07 64025500.0 30455.0 35776.0 35038.0 39584.0 43722.0 39576.0 41954.0 36734.0 38016.0 31553.0 True False 35610.429986331525 39327.60484465292 35873.438802354976 37366.236813059535 35154.987961003164 37500.56489043378 37979.81339934349 35769.77142289022 38571.912080793925 37273.30912658944 0.9553868658505644 1.0551143905974802 0.9624430897863091 1.0024931429123851 0.943167880308348 1.0060970106805522 1.0189546967873067 0.9596618132671604 1.0348400231864068 1.0 15.18585528685322 STSAPQMSPGS(ph)SDNQSSSPQPAQQK ddPTM_PC-9_Lapatinib_30min_R1 1 STSAPQMSPGSSDNQSSSPQPAQQK 25 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 STSAPQMS(0.273)PGS(0.593)S(0.134)DNQSSSPQPAQQK 167.51 1.5263999999999998e-10 7875000.0 69627.0 59541.0 69129.0 62855.0 67870.0 64032.0 51703.0 58664.0 66552.0 54765.0 True False 68634.10621197203 59403.136472688166 63445.480465656925 67477.56637813334 63878.020037553964 61293.50062588241 54379.928355278076 61389.7436034611 59056.21293637116 64231.05728022446 1.0685501549902587 0.9248351029553624 0.9877695176160615 1.0505442263505824 0.9945036364397635 0.9542657901219622 0.8466298183140859 0.9557641770651946 0.9194339224204777 1.0 15.970983423781396 -6.865207158408721 3.908545641483522 0.9239065752281506 1.0024941774226972 0.32278344135538206 0.05091705439716703 0.2617223056478564 7.478413286884603 0.01827210125430385 0.016133787714289565 1.3639323858349655e-07 6.865207158408721 0.07858760219454664 STSAPQMSPGSS(ph)DNQSSSPQPAQQK ddPTM_PC-9_Lapatinib_30min_R1 1 STSAPQMSPGSSDNQSSSPQPAQQK 25 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 S(0.001)T(0.001)S(0.001)APQMS(0.228)PGS(0.295)S(0.39)DNQS(0.011)S(0.058)S(0.015)PQPAQQK 86.54299999999999 5.2283e-06 26958000.0 37907.0 26803.0 44225.0 32740.0 39374.0 35212.0 28048.0 26882.0 43149.0 25044.0 True False 37366.439228707575 26740.939300271413 40588.99121343682 35147.80881743832 37058.09873226239 33706.064843181084 29500.188200082004 28131.035857565832 38289.105240886485 29372.82203096763 1.2721433163389038 0.910397348680987 1.3818553481393119 1.1966098722275358 1.261645840266632 1.1475255870084575 1.0043361910878055 0.957723293591178 1.3035555521535678 1.0 14.842194260618985 -7.035456093814626 6.63213772349186 1.0640586357886779 1.1984189567414871 0.1724883617420755 0.14226599769532702 0.38721696667144706 53.008621028236455 0.05288524156462583 0.041897836498296176 9.216030560003955e-08 7.035456093814626 0.13436032095280925 STSAPQMSPGSSDNQSS(ph)SPQPAQQK ddPTM_PC-9_AZD4547_30min_R2 1 STSAPQMSPGSSDNQSSSPQPAQQK 25 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 STSAPQMSPGSSDNQSS(0.5)S(0.5)PQPAQQK 181.03 1.9899000000000002e-15 11672000.0 47758.0 41512.0 58371.0 84423.0 67039.0 63436.0 57968.0 66422.0 53197.0 59242.0 True False 62944.050571889675 54929.94218859545 57596.96240106613 64960.581672347864 57731.79202737249 59469.336891848274 63127.03970110407 56158.006125716056 56008.884816172074 57167.95561186142 1.1010372838805838 0.9608519598206234 1.0075043227383786 1.136311085066502 1.0098628052984648 1.0402564908147485 1.1042381877305796 0.9823336434662391 0.9797251662529479 1.0 15.802919078403136 -7.806883558791212 24.97744433842281 0.9857718498839125 1.0474990150634755 0.2554371791641996 0.049799920280984 195.62033826888293 107516.12482649718 0.02737425665801034 0.013150232891285939 1.5599706995408016e-08 7.806883558791212 0.061727165179563004 STSAPQMSPGSSDNQSS(ph)SPQPAQQK ddPTM_PC-9_Lapatinib_30min_R1 1 STSAPQMSPGSSDNQSSSPQPAQQK 25 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 STSAPQMSPGSS(0.001)DNQS(0.097)S(0.596)S(0.306)PQPAQQK 110.9 1.5971e-07 8154200.0 81148.0 71475.0 80649.0 75323.0 81392.0 73762.0 62503.0 68558.0 77575.0 58844.0 True False 79990.81463927939 71309.50402891081 74018.35053414294 80862.50469016202 76604.68258282883 70607.37120762018 65739.09951047228 71743.45496328405 68837.68659903512 69015.10699529861 1.15903340763825 1.033244852228781 1.0724949037489018 1.1716638314517207 1.1099697720971036 1.0230712416693062 0.9525320233865682 1.0395326195490981 0.9974292527536677 1.0 16.07462457334825 -6.832537719694812 4.478721699556451 0.9993822348738619 1.1066445646613 0.6230711353017746 0.041786251217788756 0.15349277736325131 5.887741399273569 0.015484301887766292 0.013815578148678486 1.4704906936137564e-07 6.832537719694812 0.107262329787438 STSAPQMSPGSSDNQSSS(ph)PQPAQQK ddPTM_PC-9_AZD4547_30min_R2 1 STSAPQMSPGSSDNQSSSPQPAQQK 25 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 STSAPQMSPGSSDNQSS(0.233)S(0.766)PQPAQQK 175.85 6.8669e-15 11552000.0 25309.0 25257.0 34188.0 43908.0 41444.0 34303.0 32462.0 35543.0 26855.0 34926.0 True False 33356.735540097055 33420.831322445425 33734.64478195763 33785.68897183763 35690.215975513136 32158.027987279642 35351.055112773254 30050.646046886977 28274.500474430883 33703.251370647034 0.9897186230865617 0.9916203916027052 1.000931465364138 1.0024459836317867 1.0589546860928853 0.9541520974824059 1.048891536427887 0.8916245413953979 0.8389250094445136 1.0 15.040600155230837 -7.773590523092024 24.982107287011793 0.8989560299248707 1.005701883326676 0.46886001670887045 0.04659727981462526 172.43942476195102 354520.74631253403 0.02360188852574504 0.011474619936832027 1.6842613276000005e-08 7.773590523092024 0.10674585340180531 STSAPQMSPGSSDNQSSS(ph)PQPAQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 STSAPQMSPGSSDNQSSSPQPAQQK 25 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 STSAPQMSPGSSDNQSS(0.152)S(0.848)PQPAQQK;STSAPQMSPGSSDNQS(0.001)S(0.222)S(0.777)PQPAQQK;STSAPQMSPGSSDNQS(0.005)S(0.422)S(0.573)PQPAQQK 166.98 1.6668e-10 23323200.0 127842.0 123184.0 134977.0 160931.0 177021.0 164636.0 160100.0 163416.0 153451.0 128828.0 True False 149483.12560540435 135412.89342530517 138195.36358312276 151914.5578153418 142335.00580588108 156002.19833488614 144934.1689763764 159126.5031535641 155694.9305742293 152183.4965981132 0.9822558223915697 0.8898001192790574 0.9080837717119198 0.9982327992930691 0.9352854217941906 1.025092745416787 0.9523645613106073 1.0456225984463086 1.0230736844310333 1.0 17.215452389999648 -6.5826103061069885 0.811812939922147 1.0177720110640236 0.9262588098141673 0.4144159538520694 0.038140716721713167 0.5855344717655202 0.8551003366773909 0.02308067225777199 0.02679350661359543 2.6145063074400924e-07 6.5826103061069885 -0.09151320124985629 STSAPQMSPGSSDNQSSS(ph)PQPAQQK ddPTM_PC-9_Lapatinib_30min_R1 1 STSAPQMSPGSSDNQSSSPQPAQQK 25 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 STSAPQMSPGSS(0.001)DNQS(0.016)S(0.35)S(0.634)PQPAQQK 129.82 1.409e-07 6126200.0 41478.0 30297.0 35706.0 35017.0 32638.0 33545.0 28758.0 30058.0 35204.0 26550.0 True False 40886.51611386637 30226.849157942142 32770.39050914584 37592.26699328766 30718.29700877685 32110.358547214295 30246.948526025328 31454.604412123845 31238.954805445497 31139.132124348747 1.3130268355133703 0.9707030060194497 1.0523861223325988 1.2072355402574944 0.9864853293312298 1.0311899001869134 0.9713484757776601 1.0101310558854149 1.0032056988839035 1.0 14.926441115316871 -6.28793583275311 24.7171887358356 1.0009875273836393 1.1180816984815853 0.36600248200164553 0.08606908772791477 805.6648611739087 751561.5271983438 0.026172636942564075 0.029686323051321337 5.153047755194394e-07 6.28793583275311 0.11709417109794606 STSAT(ph)DTHHVEMAR ddPTM_PC-9_Lapatinib_30min_R1 1 STSATDTHHVEMAR 14 0 H3BQP2;H3BNP3;H3BTL2;H3BS02;O14874-2;O14874-3;O14874 H3BQP2 BCKDK [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial 1 S(0.19)T(0.223)S(0.223)AT(0.308)DT(0.056)HHVEMAR 77.562 0.014969 18912000.0 14383.0 15191.0 15260.0 12460.0 13875.0 7685.3 8263.3 10855.0 16264.0 10960.0 True False 14177.895782480842 15155.82617283226 14005.381705303464 13376.34996534152 13058.899779299554 7356.6176343093175 8691.133241362579 11359.362928125769 14432.177052487365 12854.421396717978 1.1029586898482087 1.1790360456598912 1.0895380875625682 1.0406030386367138 1.0159072412729353 0.572302510339954 0.6761201436559112 0.88369305607377 1.122740309118248 1.0 13.649977052585882 -6.537310592923301 24.99249310228065 0.8284772272621206 1.0975932837236164 0.3930012219052399 0.14760496687211477 243.06151036804366 420921.42344480625 0.05198399604031419 0.05200471510061731 2.9019465368276824e-07 6.537310592923301 0.26911605646149583 STSEGAWPQLPS(ph)GLSMMR ddPTM_PC-9_Lapatinib_30min_R1 1 STSEGAWPQLPSGLSMMR 18 0 G3V1A6;P57764 G3V1A6 GSDMD Gasdermin-D 1 S(0.07)T(0.094)S(0.094)EGAWPQLPS(0.62)GLS(0.123)MMR 111.86 0.00019218 13758000.0 40500.0 33724.0 57826.0 31505.0 35504.0 37263.0 26510.0 25313.0 33867.0 27200.0 True False 39922.4625732096 33645.9141499964 53071.76949481512 33821.98279759911 33415.72452354967 35669.3483542956 27882.558085573783 26489.134389649716 30052.541824679658 31901.4837582782 1.2514296474642819 1.0546817948950584 1.6636144543290525 1.0602009315263448 1.0474661547639939 1.1181093840200982 0.8740207288426973 0.8303417668708272 0.9420421336007999 1.0 14.961335905763057 -6.5255012474562495 1.2132865002538578 0.9103858780380077 1.2844357397190531 0.4545482477009526 0.165729563003693 0.41792932387632886 1.288861789701124 0.07572092062753041 0.08540107470457117 2.9819389826688034e-07 6.5255012474562495 0.37404986168104537 STSEGAWPQLPSGLS(ph)MMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSEGAWPQLPSGLSMMR 18 0 G3V1A6;P57764 G3V1A6 GSDMD Gasdermin-D 1 S(0.002)T(0.002)S(0.006)EGAWPQLPS(0.345)GLS(0.645)MMR 59.265 0.017541 25937000.0 39455.0 31811.0 39266.0 54035.0 51064.0 43022.0 44163.0 35376.0 37253.0 35290.0 True False 46133.95222822885 34968.985848425014 40202.25035713427 51007.594133833634 41058.37576599113 40765.85058409744 39979.56092756843 34447.417483970305 37797.75464924808 41687.79764451372 1.1066536213217362 0.8388302530783147 0.9643649371922397 1.2235617378685497 0.9849015320048834 0.9778844862883369 0.9590230999605206 0.826318957353309 0.90668629155137 1.0 15.347337536505885 -7.254277803166537 2.0993632160690185 0.9015056553670826 1.0185590330491192 0.17724308943566303 0.10156808089498108 0.5713437763012341 4.922810380960976 0.05248810141868563 0.03394938177035415 5.568294504382826e-08 7.254277803166537 0.11705337768203661 STSFRGGMGS(ph)GGLATGIAGGLAGMGGIQNEK ddPTM_PC-9_AZD4547_30min_R2 1 STSFRGGMGSGGLATGIAGGLAGMGGIQNEK 31 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.101)T(0.101)S(0.101)FRGGMGS(0.597)GGLAT(0.1)GIAGGLAGMGGIQNEK 48.696999999999996 0.020224000000000002 6872500.0 3800.4 3924.6 8046.4 14164.0 8409.7 7026.9 5807.8 6683.8 7182.0 7776.0 True False 5008.84814676933 5193.150200264063 7939.69947857564 10898.708631618572 7242.158316988533 6587.506832166723 6324.682948800582 5650.972288444513 7561.625857656407 7503.764606830191 0.6675113638572964 0.692072642515608 1.0580954886762632 1.4524321061055385 0.965136660923034 0.8778935877293569 0.8428679842973263 0.7530849626200692 1.0077109629443264 1.0 12.873398855867546 -10.19110336805657 15.65611040009335 0.9999739466503745 0.9291764915216594 0.010570237966422646 0.2153256926438057 0.0 0.0 0.22954426778994527 0.05567266246194178 6.440159626199591e-11 10.19110336805657 -0.07079745512871516 STSFRGGMGS(ph)GGLATGIAGGLAGMGGIQNEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STSFRGGMGSGGLATGIAGGLAGMGGIQNEK 31 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.131)T(0.131)S(0.131)FRGGMGS(0.352)GGLAT(0.255)GIAGGLAGMGGIQNEK;S(0.018)T(0.059)S(0.166)FRGGMGS(0.478)GGLAT(0.28)GIAGGLAGMGGIQNEK 76.711 1.984e-06 51602100.0 41442.0 21751.8 42488.0 77239.0 77006.0 105864.0 76484.0 124192.0 81723.0 53263.0 True False 48457.31208319 23911.174951361845 43501.07505663731 72911.54924221666 61917.2270921964 100312.30547707892 69238.88182379233 120932.09159230089 82918.04427027356 62919.160270324006 0.7701519199397997 0.38003010289124306 0.6913804136886218 1.1588131330577467 0.9840758653830896 1.59430458140414 1.1004419246270367 1.922023292630287 1.3178504594471214 1.0 15.941211795981316 -6.016701070064633 1.1337026421090775 1.4222454924307242 0.5345553920422047 0.5607893191617301 0.280224755352832 0.3352696830808291 0.8779871511962918 0.10558113135944068 0.20676742575347842 9.62274395127286e-07 6.016701070064633 -0.8876901003885195 STSFRGGMGS(ph)GGLATGIAGGLAGMGGIQNEK ddPTM_PC-9_Lapatinib_30min_R1 1 STSFRGGMGSGGLATGIAGGLAGMGGIQNEK 31 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.047)T(0.047)S(0.147)FRGGMGS(0.752)GGLAT(0.006)GIAGGLAGMGGIQNEK 62.11600000000001 0.00024531 45886000.0 200530.0 124430.0 196250.0 122630.0 160820.0 137350.0 109140.0 123920.0 184180.0 114610.0 True False 197670.40542730186 124141.88997995635 180115.08254690692 131648.61928168815 151360.88378428508 131475.86067848795 114790.73517387868 129677.77559220164 163435.70889861797 134420.18579177413 1.470541081779983 0.9235360689968132 1.3399407349869108 0.9793813221298524 1.1260279316884239 0.9780961088846646 0.8539694726482318 0.9647195086687441 1.2158568888737502 1.0 17.036390277396997 -4.751387474874602 24.89867422214361 1.0433349763680042 1.4705419992240683 0.46319101412600494 0.13827239100235092 366.83358919095394 908585.3597206109 0.0344388561398907 0.4554004607784238 1.7726072658370388e-05 4.751387474874602 0.42720702285606404 STSFRGGMGSGGLAT(ph)GIAGGLAGMGGIQNEK ddPTM_PC-9_AZD4547_30min_R2 1 STSFRGGMGSGGLATGIAGGLAGMGGIQNEK 31 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.091)T(0.108)S(0.108)FRGGMGS(0.086)GGLAT(0.609)GIAGGLAGMGGIQNEK 49.708999999999996 0.035786 0.0 3604.4 2860.5 3166.5 9208.6 5916.2 3792.7 2300.5 4424.7 3512.6 4717.8 True False 4750.5242238225865 3785.1006848737075 3124.510141045655 7085.699541451768 5094.837751045526 3555.5418694386926 2505.240043340978 3740.9642844909213 3698.2688648849735 4552.63125798656 1.0434678221498541 0.8314094576040187 0.6863086342792226 1.5563965407963831 1.1190973883746431 0.7809861304276071 0.5502839789508764 0.8217147562584268 0.8123365709439346 1.0 12.152484897145133 -6.774329302444336 22.66113173346334 0.7667473781491867 1.0435640600581841 0.2239360351543639 0.23407460392254906 116.5187097965433 204842.4148546333 0.08724935764705723 0.07757088031157246 1.6813986622756322e-07 6.774329302444336 0.27681668190899744 STSFRGGMGSGGLAT(ph)GIAGGLAGMGGIQNEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STSFRGGMGSGGLATGIAGGLAGMGGIQNEK 31 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.064)T(0.064)S(0.165)FRGGMGS(0.153)GGLAT(0.553)GIAGGLAGMGGIQNEK;S(0.005)T(0.011)S(0.081)FRGGMGS(0.216)GGLAT(0.687)GIAGGLAGMGGIQNEK 57.838 0.00084073 82580000.0 83173.0 31066.0 76918.0 156042.0 156107.0 197691.0 147327.0 224890.0 173163.0 123499.0 True False 97252.5461583698 34150.027171958485 78752.0168331394 147299.47263498945 125518.95397347589 187323.7359448841 133371.1200048881 218986.87579065154 175695.18128278942 145888.3910824536 0.6666229261751495 0.23408323937617134 0.5398100304542403 1.0096723361061561 0.8603765730923356 1.2840208501512087 0.9141996769949231 1.5010575835803408 1.204312282692113 1.0 17.154505561297043 -5.947915676879913 1.2209386117895453 1.1880587410374461 0.40690221588235886 0.6722613425859763 0.20225878207899922 0.2629101377492993 0.7942685917431387 0.07335063847855415 0.15000918027551316 1.1274163353886025e-06 5.947915676879913 -0.7811565251550873 STSFRGGMGSGGLAT(ph)GIAGGLAGMGGIQNEK ddPTM_PC-9_Lapatinib_30min_R1 3 STSFRGGMGSGGLATGIAGGLAGMGGIQNEK 31 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 S(0.022)T(0.026)S(0.056)FRGGMGS(0.135)GGLAT(0.76)GIAGGLAGMGGIQNEK;S(0.027)T(0.05)S(0.119)FRGGMGS(0.106)GGLAT(0.699)GIAGGLAGMGGIQNEK;S(0.085)T(0.086)S(0.086)FRGGMGS(0.246)GGLAT(0.498)GIAGGLAGMGGIQNEK 67.351 0.0015421 84621000.0 81889.0 43199.899999999994 65931.0 49454.6 65269.2 58943.2 45168.0 46458.8 64310.0 50459.0 True False 80721.24784339657 43099.873285743924 60510.407681019875 53091.65625970935 61430.19398018446 56422.33673931022 47506.57803127863 48617.4454541879 57066.730585677724 59180.77091760882 1.363977633136552 0.728274955149661 1.0224673782175324 0.8971099131781047 1.0380093572236035 0.9533896883138128 0.8027367216526642 0.8215074710985579 0.9642782562789821 1.0 15.85284086945349 -7.013105885731431 22.75900317266599 0.8816572078467302 0.9894384615070454 0.09140984121064966 0.15847342339120774 472.811636901159 821060.273665256 0.05551087564068405 0.04514402101341203 9.702733751733982e-08 7.013105885731431 0.10778125366031521 STSLSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSLSSPR 8 0 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 S(0.002)T(0.002)S(0.011)LS(0.123)S(0.863)PR 72.87899999999999 0.031477 9387700.0 89766.0 94948.0 118580.0 117850.0 140930.0 112620.0 113110.0 114360.0 105300.0 83169.0 True False 104961.61084068408 104373.80995052832 121407.39691715418 111247.24657485502 113315.7781744701 106714.00894382068 102395.4019545157 111358.17117443575 106839.81329197169 98246.88133455827 1.068345472293011 1.0623625761219446 1.235737921326254 1.1323234393163772 1.1533778643680097 1.0861821514764367 1.0422254687742256 1.1334524787125795 1.0874626435026682 1.0 16.584123991963168 -6.874980605228753 6.006298251859003 1.0752917354369096 1.1324096361575697 0.2300796721873707 0.05517641833704619 0.37532032894398054 18.360729407616667 0.020278469292567745 0.01789644351627833 1.3335809860414409e-07 6.874980605228753 0.05711790072066014 STSQGS(ph)INSPVYSR ddPTM_PC-9_Lapatinib_30min_R1 1 STSQGSINSPVYSR 14 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4;H0Y7N6;F6XFR5 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 STS(0.002)QGS(0.986)INS(0.012)PVYSR 82.65100000000001 0.008992299999999998 5084000.0 11909.0 10349.0 11611.0 9657.2 11953.0 10275.0 9297.2 10441.0 11932.0 7810.6 True False 11739.175476156866 10325.037526340659 10656.388399756126 10367.422703474815 11249.948040502175 9835.562202194862 9778.563524451023 10926.126976744472 10588.092510469713 9160.651803029694 1.2814781882959878 1.1271073006973007 1.1632784029878473 1.1317341742042861 1.228072879790223 1.0736749320547208 1.067452811733 1.1927237506321202 1.1558230503824982 1.0 13.161234537956311 -14.522878745280336 0.09871581545680033 0.5524927986015621 1.2532789666395627 0.42345359856251097 0.05920451245033637 208.08728657023104 1.3963194162680013 19.647691816383272 1.068403523040167 3.0000000000000132e-15 14.522878745280336 0.7007861680380006 STSQGSINS(ph)PVYSR ddPTM_PC-9_AZD4547_30min_R2 1 STSQGSINSPVYSR 14 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4;H0Y7N6;F6XFR5 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 STSQGS(0.083)INS(0.917)PVYSR 125.98 3.3336e-05 6797400.0 5757.2 5060.9 7065.8 10236.0 8967.4 7065.6 5345.2 9330.0 6544.5 7207.7 True False 7587.869842800861 6696.736953706464 6972.102875288293 7876.248344623534 7722.431298591261 6623.786915048913 5820.912444975528 7888.262882071172 6890.428909138443 6955.360616853133 1.090938379875679 0.9628166420990433 1.0024071014225477 1.1323997098783132 1.1102848182852638 0.9523283234228282 0.836895851362647 1.1341270879553789 0.9906645088167882 1.0 12.763909601249644 -6.774030114538575 24.896273320556727 0.982066889723618 1.0552313072203527 0.1798136845249445 0.08189539695578664 447.47236847217613 884803.4151419447 0.030497116320814133 0.027081372375926723 1.6825573863296887e-07 6.774030114538575 0.07316441749673475 STSQGSINS(ph)PVYSR ddPTM_PC-9_Lapatinib_30min_R1 1 STSQGSINSPVYSR 14 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4;H0Y7N6;F6XFR5 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 STSQGS(0.033)INS(0.967)PVYSR 162.26 0.00053866 5663100.0 17899.0 13249.0 17161.0 15762.0 12188.0 13801.0 14274.0 14314.0 14153.0 11959.0 True False 17643.756977725407 13218.32275451614 15750.088823375674 16921.19006049062 11471.125802529947 13210.763401702328 15013.03787678161 14979.080695826106 12558.940102302871 14026.097215634152 1.2579234769639869 0.9424091784978057 1.1229131369359024 1.206407584401273 0.8178416009938735 0.941870229373356 1.0703645957941434 1.0679435958229144 0.8953980504501339 1.0 13.775826012104599 -1.5228787452803376 0.6600561732423178 0.995754029534917 20.3870551662017 0.26291773975751775 0.11330881222735363 375.7409761882287 2.3343455568782656 0.04845496895674585 10670.254606309782 0.029999999999999995 1.5228787452803376 19.391301136666783 STSS(ph)HGTDEMESSSYR ddPTM_PC-9_AZD4547_30min_R2 1 STSSHGTDEMESSSYR 16 0 Q8IWS0-5;Q8IWS0;Q8IWS0-3;Q8IWS0-4;A0A0D9SGE8;Q5JRC6;Q8IWS0-2 Q8IWS0-5;A0A0D9SGE8 PHF6 PHD finger protein 6 1 ST(0.002)S(0.305)S(0.487)HGT(0.202)DEMES(0.004)S(0.001)SYR 87.51899999999999 0.021159999999999998 0.0 2645.6 2380.9 9551.4 9980.5 8586.1 7038.3 5859.5 9205.1 6778.5 8639.9 True False 3486.845768101497 3150.479363962875 9424.742195226103 7679.649922187883 7394.068221874176 6598.193988364584 6380.984148644414 7782.663307154703 7136.79767141798 8337.419730780894 0.4182164123545828 0.3778722273429069 1.1304147445559118 0.9211063098857082 0.8868533024163385 0.7913952039627719 0.7653427984543562 0.9334618573204265 0.855995967801604 1.0 13.025385251356695 -5.2457262010987815 24.997761812078686 0.8982810703425494 0.39804420783198907 0.8107567761929529 0.09890456389527966 341.46297506371445 543224.1111035735 0.02622070791859355 0.0688633860180542 5.679025240318428e-06 5.2457262010987815 -0.5002368625105604 STSS(ph)SSDTMSTFKPMVAPR ddPTM_PC-9_Lapatinib_30min_R1 1 STSSSSDTMSTFKPMVAPR 19 1 G5EA48;Q7Z6B7-2;Q7Z6B7 G5EA48 SRGAP1 SLIT-ROBO Rho GTPase-activating protein 1 1 S(0.119)T(0.119)S(0.119)S(0.533)S(0.089)S(0.016)DT(0.005)MSTFKPMVAPR 95.751 0.00094351 0.0 10486.0 8658.4 9760.3 7187.6 10490.0 11244.0 7599.6 9764.6 9533.7 9971.2 True False 10336.467717103116 8638.352006770512 8957.845809847544 7716.200081130713 9872.998824133505 10763.12033104419 7993.070102871621 10218.29896342487 8459.914311688326 11694.708634211163 0.8838585073308529 0.7386547435222348 0.7659742615256504 0.659802678500095 0.8442278583368454 0.9203410420639513 0.6834774899384035 0.873754044075346 0.723396757995328 1.0 13.5135682979123 STSS(ph)TSSGSNSNALVPVSWK ddPTM_PC-9_AZD4547_30min_R2 1 STSSTSSGSNSNALVPVSWK 20 0 H0Y9X0;A0A286YEZ9;A0A2C9F2R7;O94915 H0Y9X0 FRYL Protein furry homolog-like 1 S(0.022)T(0.022)S(0.1)S(0.207)T(0.207)S(0.162)S(0.026)GS(0.127)NS(0.127)NALVPVSWK 113.88 2.1874e-05 14596000.0 35763.0 33705.0 54905.0 56893.0 50420.0 41694.0 40508.0 44120.0 39493.0 36576.0 True False 47134.89008338897 44599.48211280134 54176.92382571029 43777.19783808778 43420.053312551165 39086.867588888315 44113.13352560591 37302.267776739536 41580.51935344256 35295.48537286794 1.3354368012069364 1.2636030257593651 1.534953358860925 1.2403058741257553 1.230187171357861 1.1074183334204792 1.2498236831024345 1.0568566314550312 1.1780690622094692 1.0 15.107196040476243 -6.292363342763817 1.8897106090743259 1.1309586224049115 1.3643698503069288 0.5652799431988312 0.09446554410695318 0.26087801258237675 1.8334049238748504 0.032131743966950475 0.041221118963146786 5.100780759994497e-07 6.292363342763817 0.2334112279020173 STSS(ph)TSSGSNSNALVPVSWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSSTSSGSNSNALVPVSWK 20 0 H0Y9X0;A0A286YEZ9;A0A2C9F2R7;O94915 H0Y9X0 FRYL Protein furry homolog-like 1 S(0.001)T(0.001)S(0.062)S(0.875)T(0.04)S(0.021)SGSNSNALVPVSWK 218.11 1.3717999999999998e-28 12111000.0 80342.0 84371.0 75127.0 81051.0 96737.0 91592.0 83871.0 75597.0 87586.0 75533.0 True False 93942.31377316867 92746.79529148617 76918.31260073416 76509.9752408873 77782.07928236501 86788.75428149906 75926.1317065437 73612.65885164234 88866.77955356718 89226.53498110102 1.0528517530470785 1.0394530652919647 0.862056479241586 0.8574800675280375 0.871737082459158 0.9726787474138908 0.8509366829343483 0.8250086016142413 0.9959680668131958 1.0 16.44518519499521 -5.250993183782998 23.011019828171698 0.8959085143437772 1.0461525074467959 0.4594628462693874 0.06089877828093021 190.95231162842148 420624.5944832821 0.015040137839700438 0.03869968779139977 5.6105678170448146e-06 5.250993183782998 0.15024399310301872 STSSTSSGS(ph)NSNALVPVSWK ddPTM_PC-9_Lapatinib_30min_R1 1 STSSTSSGSNSNALVPVSWK 20 0 H0Y9X0;A0A286YEZ9;A0A2C9F2R7;O94915 H0Y9X0 FRYL Protein furry homolog-like 1 S(0.001)T(0.001)S(0.015)S(0.003)T(0.003)S(0.103)S(0.022)GS(0.748)NS(0.105)NALVPVSWK 169.72 2.3478e-08 10609000.0 45460.0 41875.0 40852.0 32355.0 38315.0 36129.0 37394.0 43867.0 40018.0 28292.0 True False 44811.732063657015 41778.041010292356 37493.306253280294 34734.49463311597 36061.38703018829 34583.846890812514 39330.078349752795 45905.2209643568 35510.751431778146 33182.23450327968 1.3504736113906943 1.259048452754533 1.1299210801965285 1.0467798553374357 1.0867678916145338 1.0422398433533553 1.1852751611970398 1.3834276579480986 1.0701736023313415 1.0 15.018123420703239 -5.070494926457546 2.725266533916993 1.1275175227537946 1.346195277590744 0.36127513185527216 0.10205465731795804 0.3633061215816649 4.91610945062799 0.02887043427028998 0.1313491678210994 8.501686250230846e-06 5.070494926457546 0.2186777548369494 STST(ph)PTSPGPR ddPTM_PC-9_Lapatinib_30min_R1 1 STSTPTSPGPR 11 0 H3BUF6;H3BRB0;A0A0C4DGL7;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 ST(0.001)S(0.22)T(0.62)PT(0.159)S(0.001)PGPR 127.51 0.00087156 15982000.0 86620.0 79668.0 88293.0 74637.0 74190.0 75262.0 59540.0 59797.0 76042.0 52617.0 True False 85384.7829158374 79483.53364078728 81033.89036083622 80126.05396173314 69826.29006315197 72043.21970429106 62622.68986854254 62575.38691968097 67477.34920224085 61711.778342254525 1.383605937302471 1.2879799574073252 1.3131024990305893 1.2983915893227505 1.131490485914929 1.1674144164949871 1.014760740182143 1.0139942260719965 1.093427397732899 1.0 15.913258248733758 -6.506389428207249 0.9229260280207174 1.0257971554637466 1.3448382687025715 0.8987248104636076 0.04283788404656818 0.16319270404636665 0.3030998602544823 0.02264752926524949 0.02750782497381285 3.116094155555882e-07 6.506389428207249 0.3190411132388249 STSTLEIQPSRAS(ph)PTSDIESVER ddPTM_PC-9_Lapatinib_30min_R1 2 STSTLEIQPSRASPTSDIESVER 23 1 Q96JK2-2;Q96JK2-3;Q96JK2 Q96JK2-2 DCAF5 DDB1- and CUL4-associated factor 5 1 STSTLEIQPS(0.003)RAS(0.734)PT(0.223)S(0.039)DIESVER;S(0.002)T(0.001)S(0.002)T(0.002)LEIQPS(0.004)RAS(0.783)PT(0.102)S(0.102)DIESVER 65.915 0.00080401 6727100.0 14983.0 13815.8 18533.2 13074.9 11946.7 18061.9 12039.8 14315.7 17849.0 11674.900000000001 True False 14769.339672454304 13783.810363940223 17009.471836220855 14036.471762587786 11244.018594115903 17289.434641345357 12663.161932806159 14980.859684032244 15838.657661697436 13692.890909173604 1.0786136959989603 1.0066399020754417 1.2422118856453677 1.0250919148989932 0.8211573924526727 1.2626577364873501 0.9247982779386948 1.0940611287566573 1.1567066273117146 1.0 13.741139447038487 STSTPNVHMVS(ph)TTLPVDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STSTPNVHMVSTTLPVDSR 19 0 P04049;P04049-2;H7C155 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 S(0.019)T(0.026)S(0.046)T(0.051)PNVHMVS(0.855)T(0.003)T(0.001)LPVDSR 110.8 0.0001222 31196000.0 25933.0 24430.0 41938.0 40382.0 45855.0 44346.0 44697.0 36775.0 39624.0 32154.0 True False 30322.94469990265 26855.248947754648 42937.9609707507 38119.527460210425 36870.041922871744 42020.41769332869 40462.976581743256 35809.69521633331 40203.426038756785 37983.26566907606 0.7983237924850144 0.7070284367259856 1.130444163091234 1.0035874164249468 0.9706917315666556 1.1062876493934395 1.065284300046008 0.9427755772323612 1.058451013375826 1.0 15.213076328271248 -5.254929735440685 24.9996304422099 1.0328997235820703 0.7526760876923959 0.7856865257694305 0.0589097415490553 214.1917615043524 822576.3691848199 0.014891249214347407 0.03742162175477808 5.559942043667807e-06 5.254929735440685 -0.28022363588967436 STSTPTS(ph)PGPR ddPTM_PC-9_AZD4547_30min_R2 4 STSTPTSPGPR 11 0 H3BUF6;H3BRB0;A0A0C4DGL7;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 ST(0.001)ST(0.002)PT(0.008)S(0.989)PGPR;ST(0.004)S(0.017)T(0.017)PT(0.114)S(0.849)PGPR;STST(0.001)PT(0.028)S(0.971)PGPR;ST(0.001)S(0.004)T(0.028)PT(0.102)S(0.865)PGPR 147.62 0.00026143 51988900.0 104221.0 114299.4 176390.0 290746.0 220080.0 191069.0 190307.0 273329.0 201708.0 235494.0 True False 137361.11006853124 151244.44580340973 174050.9533488215 223719.0016809217 189525.69085732385 179121.42522524355 207243.95432649102 231092.2835255773 212369.8730849564 227249.42673879463 0.6044508540231305 0.6655437946483946 0.7659027168806872 0.9844645370131963 0.8339985432621959 0.7882150806528967 0.9119668960252281 1.0169103035458908 0.9345232510929891 1.0 17.793917129506838 -3.96579148845225 0.392413972537721 0.967239499548712 3.056058423601776e-15 0.7438357516255616 0.06881918569877885 6.091693382183251 0.45243363808907244 0.06015965153633001 3.145132576035327 0.0001081953289249536 3.96579148845225 -0.9672394995487089 STSTPTS(ph)PGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 STSTPTSPGPR 11 0 H3BUF6;H3BRB0;A0A0C4DGL7;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 S(0.083)T(0.269)S(0.132)T(0.042)PT(0.132)S(0.341)PGPR;STS(0.001)T(0.005)PT(0.115)S(0.878)PGPR;STSTPT(0.005)S(0.995)PGPR;STSTPT(0.001)S(0.999)PGPR 104.07 0.0027285 124218400.0 142080.7 130889.4 255753.0 260283.0 331952.0 320237.0 262106.0 335069.0 280100.0 259303.0 True False 166132.15628826016 143883.23461409073 261851.12146865326 245700.18735887102 266908.38853737 303443.207974981 237277.42219689008 326273.793784951 284195.93260286195 306312.5812585819 0.5423615171327726 0.46972681965233376 0.8548493842229898 0.8021224147873204 0.871359535545986 0.990632532063126 0.7746251271232835 1.0651661529681613 0.927797126174685 1.0 18.224645098789942 -5.327686555269915 1.0391274303964968 0.9398952469446225 0.4165709109222842 0.7538620675781657 0.09124809178059315 0.41472842871518073 0.6424228626375978 0.03078576833945281 0.19767825815992318 4.7023336917955725e-06 5.327686555269915 -0.5233243360223383 STSTPTS(ph)PGPR ddPTM_PC-9_Lapatinib_30min_R1 2 STSTPTSPGPR 11 0 H3BUF6;H3BRB0;A0A0C4DGL7;Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 H3BUF6;Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 STSTPT(0.003)S(0.997)PGPR;S(0.02)T(0.001)S(0.001)T(0.005)PT(0.101)S(0.871)PGPR 142.19 0.00013857 46832000.0 139055.0 133202.0 178123.0 146737.0 152834.0 140168.0 143081.0 130366.0 174825.0 118132.0 True False 137072.05020043597 132893.5789529062 163478.41451466343 157528.52848028252 143844.60460320493 134173.3413875669 150489.03407929002 136423.28028448136 155134.36751113544 138550.95879900453 0.9893258869416126 0.959167515727513 1.1799154327890367 1.136971767252861 1.0382072116287544 0.9684042791952944 1.0861637868389207 0.9846433504829816 1.1196917643578954 1.0 17.08005716901495 -6.497143658001083 24.22727481638033 1.0307848869035525 1.0694002324314222 0.047965623787486256 0.07299453455266056 1775.2065997827324 1671200.6769803998 0.023928243447551772 0.027018670235652516 3.183144411861542e-07 6.497143658001083 0.038615345527869716 STSYGYS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 STSYGYSR 8 0 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 1 STSYGY(0.001)S(0.999)R;STSYGYS(1)R;STS(0.026)Y(0.005)GY(0.002)S(0.967)R 77.288 0.023754 402068000.0 174913.0 181611.0 208366.0 199628.0 225933.0 178686.0 175519.0 128873.0 175782.0 147338.0 True False 204522.31621077686 199640.1398547139 213334.23567245586 188443.49036270834 181663.05052361122 169315.3916012746 158892.5696724838 125490.22030223072 178352.47920312782 174049.2130730334 1.1750832571989656 1.1470327060366667 1.2257121529353765 1.0827023405364946 1.0437453138462796 0.9728018220354009 0.9129174838946864 0.7210042383217977 1.0247244216398077 1.0 17.40913576567049 -6.519621050678984 1.2622545337144535 0.8942932373695093 1.1772638157056943 0.6487954613165472 0.08155831036634945 0.254464692823066 0.8445461562790142 0.03527204485050671 0.03979592482290682 3.022587968688062e-07 6.519621050678984 0.282970578336185 STSYGYS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 STSYGYSR 8 0 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 1 STSYGYS(0.999)R 72.096 0.033615 263030000.0 72308.0 67482.0 63588.0 50489.0 57750.0 57460.0 58111.0 58620.0 63855.0 47851.0 True False 71276.8746603367 67325.74957508183 58360.04009677832 54202.129486366626 54353.25854086846 55002.56974580215 61119.70324069329 61343.69920283122 56662.97747704016 56121.98159255038 1.2700348889640416 1.1996324374978706 1.0398784654554147 0.9657914412195561 0.9684843086168451 0.9800539500747633 1.0890510546193242 1.0930422886381825 1.0096396433115538 1.0 15.776278329050278 -5.188187290601608 2.8759391416152393 1.0172664651416077 1.2600185363772478 0.8120030294912269 0.04241750580302901 0.1268155625474029 1.99829807909943 0.01308767314722023 0.045282710230105896 6.483547686039354e-06 5.188187290601608 0.24275207123564013 STT(ph)PPPAEPVSLPQEPPK ddPTM_PC-9_AZD4547_30min_R2 4 STTPPPAEPVSLPQEPPK 18 0 Q9UN86-2;Q9UN86 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 S(0.019)T(0.026)T(0.954)PPPAEPVSLPQEPPK;S(0.005)T(0.005)T(0.989)PPPAEPVSLPQEPPK;S(0.028)T(0.028)T(0.944)PPPAEPVSLPQEPPK;S(0.005)T(0.005)T(0.99)PPPAEPVSLPQEPPK 229.02 8.533499999999998e-35 84943000.0 450786.0 480422.0 540047.0 550715.0 553565.0 622466.0 543590.0 627752.0 554304.0 550491.0 True False 594126.5710687198 635709.0163357441 532885.6239195588 423756.16521193297 476712.0549774373 583543.1026187222 591968.4569266331 530747.3527058894 583603.3778059552 531218.4776464188 1.1184222614036647 1.1966997442413412 1.0031383439080024 0.7977059967669023 0.8973935867018895 1.0984992562836469 1.1143596878432562 0.999113123958683 1.0986127221922501 1.0 19.018945804000467 -5.272293392570737 22.938222524278533 0.9976263987618218 1.1575609848441075 0.30961981874086475 0.09333644916212641 272.6715637193325 576251.6767434686 0.02737553937622618 0.0580653861409556 5.342033503270694e-06 5.272293392570737 0.15993458608228572 STT(ph)PPPAEPVSLPQEPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 STTPPPAEPVSLPQEPPK 18 0 Q9UN86-2;Q9UN86 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 S(0.177)T(0.177)T(0.646)PPPAEPVSLPQEPPK;S(0.118)T(0.118)T(0.764)PPPAEPVSLPQEPPK;S(0.006)T(0.006)T(0.988)PPPAEPVSLPQEPPK;S(0.083)T(0.083)T(0.835)PPPAEPVSLPQEPPK;S(0.03)T(0.049)T(0.921)PPPAEPVSLPQEPPK 207.05 7.3923e-20 44836000.0 297260.0 310606.0 303379.0 329210.0 368677.0 265864.0 344128.0 259983.0 257119.0 229090.0 True False 347580.2468473788 341440.9109564582 310612.70593126514 310765.4310132204 296437.3884199888 251921.6238131765 311529.7045690345 253158.7217247585 260878.87895364242 270622.20352455793 1.2843744612250088 1.261688459075287 1.1477724365771718 1.1483367845130255 1.095391969170365 0.9308978366600121 1.1511609192139491 0.9354691463880026 0.963996581049081 1.0 18.045920686259187 -5.503274687972338 0.5169540316724801 0.9768933069139631 1.3885128318570192 0.7463976014798096 0.06186216068694366 1.1048839699661996 0.382424948900883 0.04222672124115349 0.25398206578048194 3.1385229739425663e-06 5.503274687972338 0.4116195249430561 STT(ph)PPPAEPVSLPQEPPK ddPTM_PC-9_Lapatinib_30min_R1 4 STTPPPAEPVSLPQEPPK 18 0 Q9UN86-2;Q9UN86 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 S(0.107)T(0.138)T(0.756)PPPAEPVSLPQEPPK;S(0.139)T(0.139)T(0.723)PPPAEPVSLPQEPPK;S(0.117)T(0.117)T(0.766)PPPAEPVS(0.001)LPQEPPK;S(0.019)T(0.027)T(0.954)PPPAEPVSLPQEPPK 150.12 0.00011082 82412000.0 307997.0 374818.0 400668.0 354525.0 437371.0 421088.0 377322.0 407613.0 412093.0 354971.0 True False 303604.90630026837 373950.131949749 367726.62366320647 380597.95116073074 411645.69768447033 403079.04784407147 396857.8869092747 426552.1880444149 365678.74680833 416327.26438087353 0.7292457935748304 0.8982119691484914 0.883263372650019 0.9141797420515412 0.9887550802050756 0.9681783595016202 0.9532354012400508 1.024559822376147 0.8783444614230017 1.0 18.66735851501702 -3.741682995079182 0.6836261057080351 0.968180104794643 2.7237745399126625e-15 0.7273940007456061 0.04219856919871266 5.597752508955204 0.6797086391686307 0.016525019013356537 5.830247647012811 0.00018126627282091893 3.741682995079182 -0.9681801047946402 STT(ph)PPPAEPVSLPQEPPKPR ddPTM_PC-9_AZD4547_30min_R2 3 STTPPPAEPVSLPQEPPKPR 20 1 Q9UN86-2 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 S(0.154)T(0.154)T(0.692)PPPAEPVSLPQEPPKPR;S(0.17)T(0.17)T(0.661)PPPAEPVSLPQEPPKPR;S(0.16)T(0.16)T(0.68)PPPAEPVSLPQEPPKPR 170.02 1.5693999999999998e-08 1120532100.0 301714.0 333566.0 353426.0 401117.0 376851.0 387310.0 379274.0 459002.0 373951.0 395218.0 True False 397652.7759589415 441384.6862613472 348739.34031555377 308645.67284587293 324531.7435717613 363091.44447288226 413028.65124890534 388073.7877166586 393717.2864239031 381381.53811499703 1.0426639368134234 1.1573310245769095 0.9144106503928338 0.8092832033018016 0.8509372141498524 0.9520425300802059 1.0829801916745267 1.0175473874135033 1.0323449015646544 1.0 18.54087548191916 -7.2330965585907 20.854142594057627 1.0346803497716768 0.9505438792669292 0.14637815877419036 0.09287924900303465 204.6516092430195 150578.0872616655 0.040986226019232797 0.03172961343632851 5.8466007966140445e-08 7.2330965585907 -0.0841364705047476 STT(ph)PPPAEPVSLPQEPPKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STTPPPAEPVSLPQEPPKPR 20 1 Q9UN86-2 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 S(0.133)T(0.176)T(0.69)PPPAEPVSLPQEPPKPR;S(0.199)T(0.199)T(0.603)PPPAEPVSLPQEPPKPR 151.01 1.0067999999999999e-05 1154619000.0 179648.0 232434.0 199828.0 212689.0 220427.0 180612.0 226982.0 180674.0 183878.0 155248.0 True False 210058.85819026397 255508.51141720888 204592.65737190982 200772.72487704124 177235.91169845965 171140.3887707456 205480.62175262917 175931.49893992653 186566.86788700047 183393.23345750815 1.1454013554918545 1.393227583156222 1.1155954530858607 1.0947662631378376 0.9664255782889878 0.9331881310135605 1.1204373131914849 0.9593129235091954 1.0173050791987244 1.0 17.48458088415829 -5.65431662938696 2.13267701937006 1.0040582989109519 1.2678083461314726 0.6238132919402752 0.07868056211904523 0.18448509450941722 1.6941498222332514 0.022167775536087023 0.04755829672209962 2.216579797357088e-06 5.65431662938696 0.26375004722052076 STT(ph)PPPAEPVSLPQEPPKPR ddPTM_PC-9_Lapatinib_30min_R1 3 STTPPPAEPVSLPQEPPKPR 20 1 Q9UN86-2 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 S(0.142)T(0.142)T(0.715)PPPAEPVSLPQEPPKPR;S(0.171)T(0.171)T(0.659)PPPAEPVSLPQEPPKPR;S(0.155)T(0.155)T(0.69)PPPAEPVSLPQEPPKPR 178.52 1.1509999999999999e-09 2426315000.0 1541094.0 1861482.0 1809253.0 1802267.0 1920474.0 1915674.0 1759110.0 1628809.0 1828942.0 1562643.0 True False 1519117.7169579717 1857171.8527981143 1660503.202258546 1934811.7273664621 1807515.4951171547 1833745.0886742023 1850188.1084086664 1704489.412399598 1622947.2923469227 1832743.7604590857 0.8288762181230651 1.0133287003159184 0.9060203821633008 1.055691346007807 0.9862347012789111 1.0005463547260234 1.0095181597809457 0.9300205785301043 0.8855287505878012 1.0 20.80557366324546 -4.752586088608805 24.984468127972676 0.9765218266718728 0.8288759337291393 0.4356407963901927 0.05034543281175072 334.70585656718725 944487.896597056 0.012629034300584695 0.1478576362394812 1.767721773971558e-05 4.752586088608805 -0.14764589294273356 STT(ph)PTSSPFR ddPTM_PC-9_AZD4547_30min_R2 1 STTPTSSPFR 10 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;H7C5N8;A0A2R8Y7F4;A0A2R8YET2;A0A2R8Y424 E7EPN9 PRRC2C Protein PRRC2C 1 S(0.013)T(0.045)T(0.929)PT(0.009)S(0.003)S(0.001)PFR 99.34299999999999 0.010783 25700000.0 60228.0 46458.0 70494.0 97587.0 92190.0 80590.0 70712.0 112210.0 82857.0 86509.0 True False 79379.25117977675 61474.63996429384 69559.20350003865 75089.8248541204 79391.00981523376 75550.69456009279 77005.23101270487 94870.52282928243 87236.65186408204 83480.34624129029 0.9508735259714928 0.7363965619717066 0.833240476734318 0.8994910566983267 0.9510143811067006 0.905011753805168 0.922435453132048 1.136441415265219 1.0449962870534173 1.0 16.349148963750558 -7.103383836751555 0.8453696112483117 1.0637925915824749 0.8423651540400284 0.5433835620473701 0.07069037546061903 0.4512673861309436 0.6542185087147627 0.053907350003182516 0.03643948675397797 7.881632178189698e-08 7.103383836751555 -0.22142743754244643 STT(ph)PTSSPFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STTPTSSPFR 10 0 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;H7C5N8;A0A2R8Y7F4;A0A2R8YET2;A0A2R8Y424 E7EPN9 PRRC2C Protein PRRC2C 1 S(0.079)T(0.079)T(0.775)PT(0.049)S(0.017)S(0.001)PFR;S(0.324)T(0.057)T(0.468)PT(0.04)S(0.085)S(0.026)PFR 112.85 0.0034046999999999997 83145000.0 573260.0 486690.0 678640.0 657040.0 837410.0 637170.0 633580.0 687850.0 585260.0 536940.0 True False 670301.5955988957 535005.3667778431 694821.3513565307 620228.1789524194 673325.5218979826 603755.6835263206 573562.7156780295 669794.666337318 593818.3202968596 634282.9715852978 1.0567863644889828 0.8434805768798667 1.0954438042376038 0.9778414473310697 1.0615538364763342 0.9518711845870957 0.9042694528665858 1.0559871482333254 0.9362041027409221 1.0 19.274767085503683 STT(ph)SVSEEDVSSR ddPTM_PC-9_Lapatinib_30min_R1 1 STTSVSEEDVSSR 13 0 Q96IZ0 Q96IZ0 PAWR PRKC apoptosis WT1 regulator protein 1 STT(0.588)S(0.319)VS(0.093)EEDVSSR 198.37 1.7054e-06 19535000.0 40889.0 47209.0 56744.0 46700.0 80659.0 86847.0 97610.0 78884.0 105510.0 115770.0 True False 40305.91536187577 47099.69046101232 52078.727358174285 50134.47378663315 75914.79620169534 83132.75626024502 102663.76819060196 82549.23862020012 93626.35273044412 135780.69024617138 0.29684570971616697 0.34688062327286917 0.38355032121102917 0.3692312485357011 0.5590986175137368 0.6122575758712431 0.756099913798286 0.6079600749601269 0.6895409985079533 1.0 17.050918798887764 -6.764969996772499 0.19534134581912252 1.0904744862732179 2.2004658655135642e-20 0.9171415397454956 0.06010646223303093 1.66321279742636 0.15886513448374148 0.2329146600782009 0.5489397602896493 1.718027072931346e-07 6.764969996772499 -1.0904744862732179 down STTS(ph)VSEEDVSSR ddPTM_PC-9_AZD4547_30min_R2 2 STTSVSEEDVSSR 13 0 Q96IZ0 Q96IZ0 PAWR PRKC apoptosis WT1 regulator protein 1 S(0.002)T(0.036)T(0.221)S(0.74)VS(0.001)EEDVSSR;STT(0.266)S(0.726)VS(0.007)EEDVSSR 197.36 8.4966e-07 50126000.0 162124.0 157159.0 231626.0 309890.0 254620.0 233980.0 232614.0 304250.0 239228.0 249182.0 True False 213676.05961131243 207957.57333825095 228554.48789826018 238449.64825277316 219270.4080611225 219349.19361174543 253316.19536697227 257235.15346946998 251873.10368635852 240458.21402509825 0.8886203387878845 0.8648387171192455 0.950495656074383 0.9916469238513289 0.9118857051738551 0.9122133527484758 1.0534728305872385 1.0697707063673882 1.047471406653918 1.0 17.875426683789833 -7.262683925638703 24.963204892802086 1.0484929677037953 0.9217258649292374 0.7336769911979264 0.036147267137150454 60.93482516633694 1222214.432708862 0.015849797609396553 0.011350437194113466 5.461552017472963e-08 7.262683925638703 -0.12676710277455794 STTS(ph)VSEEDVSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 STTSVSEEDVSSR 13 0 Q96IZ0 Q96IZ0 PAWR PRKC apoptosis WT1 regulator protein 1 S(0.01)T(0.01)T(0.048)S(0.929)VS(0.003)EEDVSSR;STT(0.025)S(0.795)VS(0.18)EEDVSSR 175.21 0.00016865 36429000.0 92339.0 92353.0 97262.0 114587.0 174895.0 160165.0 171681.0 213065.0 174001.0 146138.0 True False 107970.16892161747 101521.19550028592 99581.09494818911 108167.06188606622 140625.58024426267 151765.6654456318 155418.13281719724 207472.26951102848 176545.4354474494 172631.66257222867 0.6254366511499188 0.5880798110127086 0.5768414291122559 0.6265771891110032 0.8145990031546227 0.8791299532444311 0.9002875283795095 1.2018204912104267 1.0226712343315538 1.0 17.397337569583 -6.779661154117807 0.9866680264059232 1.0741381597306596 0.5835366899466677 0.8852704136941553 0.06919203485579119 0.1613637136265905 0.33699200616345254 0.040563205175385676 0.03632606077016225 1.6608822580504284e-07 6.779661154117807 -0.4906014697839919 STTS(ph)VSEEDVSSR ddPTM_PC-9_Lapatinib_30min_R1 1 STTSVSEEDVSSR 13 0 Q96IZ0 Q96IZ0 PAWR PRKC apoptosis WT1 regulator protein 1 STT(0.036)S(0.773)VS(0.191)EEDVSSR 187.74 3.2532e-05 19218000.0 22427.0 27569.0 35608.0 27725.0 48984.0 48701.0 60546.0 49121.0 62685.0 67646.0 True False 22107.186867391916 27505.165674334305 32680.447690854904 29763.988987888737 46102.85742624933 46618.17175757592 63680.77562614676 51403.3409850268 55624.75519768635 79338.52096737071 0.2786437987227398 0.34668109940751557 0.411911481237409 0.37515180047444635 0.5810904572472417 0.5875855913264177 0.802646367107556 0.6478989065874732 0.7011065308434846 1.0 16.275733882491068 -6.459142890271111 0.2205138022309405 1.0469255431908204 4.626685863805101e-19 0.9098674307926325 0.06441289459226747 1.5574103434490505 0.14752881304096416 0.1608918013609209 0.4857255009385017 3.4742183494384125e-07 6.459142890271111 -1.0469255431908204 down STTSVS(ph)EEDVSSR ddPTM_PC-9_AZD4547_30min_R2 2 STTSVSEEDVSSR 13 0 Q96IZ0 Q96IZ0 PAWR PRKC apoptosis WT1 regulator protein 1 S(0.001)T(0.003)T(0.019)S(0.239)VS(0.737)EEDVS(0.001)SR;STTS(0.002)VS(0.997)EEDVS(0.001)SR 118.13 0.00024808 17896100.0 22207.5 21439.9 32204.0 36052.0 30992.0 26486.0 29165.0 36140.0 28169.0 24516.0 True False 29269.02305530468 28369.92839490429 31776.9539182802 27740.768397847554 26689.295760860485 24829.82623301425 31760.628499908566 30555.393414582206 29657.955831846724 23657.70230208965 1.2371879010718378 1.1991835907242108 1.3431969644606354 1.1725892922152992 1.1281440361392603 1.0495451297829996 1.3425068966694707 1.2915621738922336 1.2536279074416743 1.0 14.53002234171615 STTSVS(ph)EEDVSSR ddPTM_PC-9_Lapatinib_30min_R1 1 STTSVSEEDVSSR 13 0 Q96IZ0 Q96IZ0 PAWR PRKC apoptosis WT1 regulator protein 1 STT(0.001)S(0.006)VS(0.992)EEDVS(0.001)SR 101.3 0.0020361 11033000.0 9339.4 15265.0 13571.0 9950.7 12295.0 12961.0 12305.0 12486.0 15273.0 10176.0 True False 9206.218443363794 15229.65483037881 12455.244765574926 10682.507672562111 11571.832272900048 12406.688243566688 12942.092691172595 13066.145142384006 13552.79390818 11934.908041332308 0.771369030367166 1.2760596711458787 1.0435978829866654 0.8950640956400373 0.969578670637857 1.03952943756253 1.0843898123347293 1.0947838975494457 1.1355591397306724 1.0 13.542899830022348 -7.093374838368305 3.5454876251649114 1.0863531542462541 1.0044771568642352 0.09394267105014331 0.12365436723374909 0.6832276680332868 16.0302539190293 0.049602295052164166 0.03821525193778972 8.06538608505966e-08 7.093374838368305 -0.0818759973820189 STTSVSEEDVSSR ddPTM_PC-9_Lapatinib_30min_R1 1 STTSVSEEDVSSR 13 0 Q96IZ0 Q96IZ0 PAWR PRKC apoptosis WT1 regulator protein 0 91.70100000000001 0.031445999999999995 0.0 4711.7 4027.2 5603.3 4978.0 6055.7 6942.7 4750.5 3923.9 5876.3 4089.5 False True 4644.510293980041 4017.875265830429 5142.618303363493 5344.098726121194 5699.515631964281 6645.776905224164 4996.457645624982 4106.218718901218 5214.449213817727 4796.364626083772 0.968339702265772 0.8376917893148212 1.072190857925336 1.114197760749613 1.1882990715445108 1.3855862561163192 1.0417176414097162 0.8561106252370022 1.0871669733907032 1.0 12.227725623198843 -5.36684546456541 5.379131507621213 1.1028068632829702 0.9044252879765685 0.2516373937711198 0.13101932490730836 0.3108054313378988 12.906814053375978 0.0382421183076844 0.0819359043835334 4.296892963322682e-06 5.36684546456541 -0.19838157530640166 STTTGHLIYK ddPTM_PC-9_AZD4547_30min_R2 2 STTTGHLIYK 10 0 Q5VTE0;P68104;A0A087WVQ9;A0A087WV01;A0A2U3TZH3;Q05639;A6PW80;Q5JR01;A0A2R8Y660;A0A2R8Y488;A0A2R8YDN5 Q5VTE0 EEF1A1P5;EEF1A1;EEF1A2 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha;Elongation factor 1-alpha 2 0 ; 89.08 0.0080389 40247000.0 86319.0 75659.0 298970.0 485060.0 387040.0 304210.0 213569.0 418910.0 219000.0 311100.0 False True 113766.64645326296 100114.29215761577 295005.46245647216 373236.91110229475 333306.17679670407 285187.7006095775 232576.22726202573 354177.0850941524 230575.8929026386 300208.48369147046 0.3789587990797187 0.33348255494506607 0.9826686402362115 1.2432590395609102 1.110249026603954 0.9499654943218392 0.7747157055729591 1.1797704073484694 0.7680525549024974 1.0 18.195605221570872 -5.2701972252866724 7.956239386894632 1.0106527632475184 0.3549341187947037 0.7576115333899074 0.14583170255679503 0.05871126263711531 32.87979216443898 0.03860921488596879 0.08737963138690347 5.3678797056017155e-06 5.2701972252866724 -0.6557186444528147 STTTGHLIYK ddPTM_PC-9_Lapatinib_30min_R1 1 STTTGHLIYK 10 0 Q5VTE0;P68104;A0A087WVQ9;A0A087WV01;A0A2U3TZH3;Q05639;A6PW80;Q5JR01;A0A2R8Y660;A0A2R8Y488;A0A2R8YDN5 Q5VTE0 EEF1A1P5;EEF1A1;EEF1A2 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha;Elongation factor 1-alpha 2 0 71.34899999999999 0.028031999999999998 82264000.0 134700.0 144130.0 213150.0 185050.0 216050.0 227960.0 180070.0 178670.0 240550.0 140300.0 False True 132779.15329904528 143796.27584032106 195625.62978279367 198659.19430870327 203342.36377064287 218210.6822007144 189393.14351072337 186971.6604669034 213456.72589620255 164550.66806200135 0.806919563821006 0.8738723308381817 1.1888473750169373 1.2072828184073376 1.2357431675332071 1.326100250887431 1.1509715866930517 1.1362558576574968 1.2972097191107956 1.0 17.32817235813262 -5.230395736594845 3.689140271307365 1.2051522915319903 0.8209406933951388 0.7288390610849793 0.08616537931877075 0.10517012539875266 3.086762730570847 0.02180035751505966 0.06223613641687429 5.883073352872552e-06 5.230395736594845 -0.3842115981368516 STTTPPRCS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 1 STTTPPRCSPAR 12 1 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 STTTPPRCS(1)PAR 60.691 0.027801 7982500.0 4869.5 3773.9 8617.0 15486.0 11283.0 6435.8 5793.6 9003.3 6312.5 8712.6 True False 6417.899708107897 4993.739372363181 8502.732949752219 11915.941956314962 9716.550208756738 6033.368408609576 6309.219176309623 7612.04686025202 6646.165862775837 8407.57452590905 0.763347346887059 0.593957193834478 1.0113181778585398 1.41728650987207 1.155690048160014 0.717611052987631 0.7504208445452291 0.9053796474589066 0.7904974071053191 1.0 13.037473946719967 -6.774284405284285 24.99750749505716 0.8217204807394191 0.9915200105139796 0.11196747110894123 0.2178117724956349 584.0339503409784 1136572.5261867284 0.08738485775182865 0.07754866095985274 1.68157249346666e-07 6.774284405284285 0.1697995297745606 STTTPPRCS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 1 STTTPPRCSPAR 12 1 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 STTTPPRCS(1)PAR 82.494 0.0056862 5827300.0 10051.0 7051.6 10323.0 7096.2 7553.9 7358.5 4476.0 5253.9 8306.5 5486.7 True False 9907.670896872341 7035.272453449014 9474.282787932358 7618.078220229258 7109.594453538806 7043.794108501308 4707.745378763795 5498.015374304928 7370.934498677226 6435.068784431803 1.5396371396746709 1.0932707464556197 1.472289280085591 1.183837885099143 1.104820273365044 1.0945949988199317 0.731576543541092 0.8543833109610477 1.1454321228872548 1.0 12.651739854153641 -6.4185019689809115 1.3260681068518405 0.9299960045827803 1.34301102617013 0.5560677081303522 0.15515958003212962 0.32204998656730044 1.160422604742295 0.06321383376984067 0.07762592912795499 3.8150306463748787e-07 6.4185019689809115 0.4130150215873497 STVLTNGEAAMQSSNS(ph)ESKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 STVLTNGEAAMQSSNSESKK 20 1 Q9NVP1 Q9NVP1 DDX18 ATP-dependent RNA helicase DDX18 1 STVLTNGEAAMQS(0.01)S(0.035)NS(0.477)ES(0.477)KK 57.802 0.030066000000000002 0.0 10740.0 15388.0 12238.0 10807.0 9357.9 8028.9 10109.0 10755.0 11591.0 8273.5 True False 12558.06987533083 16915.618944250866 12529.800332873447 10201.51882676673 7524.286671247224 7607.85034992934 9151.40233717794 10472.692645864445 11760.496446982386 9773.420057010035 1.2849207137396588 1.730777849061962 1.2820282214194185 1.0438023503808822 0.7698724323068864 0.7784225281990792 0.9363561868615328 1.0715484021740018 1.2033143340183268 1.0 13.254647783998163 -5.652728191730013 2.9285972827065447 0.9522819428078526 1.5094027411354058 0.653801394389074 0.15875607966890257 0.15114617737203975 2.588894521608869 0.04726047516192504 0.09060377004848308 2.224701810623127e-06 5.652728191730013 0.5571207983275532 STVTGERQS(ph)GDGQESTEPVENK ddPTM_PC-9_AZD4547_30min_R2 3 STVTGERQSGDGQESTEPVENK 22 1 O15234;J3KSY7 O15234 CASC3 Protein CASC3 1 STVTGERQS(1)GDGQESTEPVENK;STVT(0.002)GERQS(0.998)GDGQESTEPVENK;S(0.001)T(0.001)VT(0.012)GERQS(0.977)GDGQES(0.007)T(0.003)EPVENK 113.49 1.3039e-06 91275000.0 70514.0 56444.0 84853.0 108806.0 91424.0 74052.0 68735.0 87688.0 75473.0 78721.0 True False 92935.98521768546 74688.41917742055 83727.79377803479 83722.45773594259 78731.35569311131 69421.51673363934 74852.28184266134 74137.83446978108 79462.34869881663 75965.00175080741 1.2234052929077657 0.9831951221751497 1.1021890587548742 1.102118815327385 1.0364161637404885 0.9138618460296616 0.9853522032185796 0.975947248878897 1.0460389240756127 1.0 16.21304727929067 -6.501154504953999 5.078486471722383 0.9817379509489885 1.0922449787475275 0.4431009728230201 0.06205192031729859 0.18420944478629828 13.339394896115989 0.019405375421373303 0.02099765049812482 3.153882396027682e-07 6.501154504953999 0.11050702779853894 STVTGERQS(ph)GDGQESTEPVENK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 STVTGERQSGDGQESTEPVENK 22 1 O15234;J3KSY7 O15234 CASC3 Protein CASC3 1 S(0.005)T(0.005)VT(0.056)GERQS(0.935)GDGQESTEPVENK;S(0.001)T(0.001)VT(0.011)GERQS(0.988)GDGQESTEPVENK;STVT(0.009)GERQS(0.991)GDGQESTEPVENK 89.507 9.8127e-05 44120000.0 54447.0 51900.0 55428.0 72722.0 79610.0 65755.0 72163.0 73880.0 63753.0 53448.0 True False 63663.80172273167 57052.289004849205 56749.61373186058 68647.62210790493 64010.99198516679 62306.6920449381 65327.19822512338 71940.72828233047 64685.267016173566 63137.69930586477 1.0083326193803521 0.903616850662623 0.8988229592741779 1.0872683493794704 1.0138315568812768 0.9868381763975761 1.034678154942767 1.139425875083288 1.024510993072645 1.0 15.946214070347743 -5.758450802516669 24.999996130051162 1.0431013803776097 0.9335934042950392 0.47319414055887343 0.05021875038114386 66.89459617789105 559572.9688455346 0.014275315221718338 0.023426399286462913 1.7440109102592073e-06 5.758450802516669 -0.10950797608257046 STVTGERQS(ph)GDGQESTEPVENK ddPTM_PC-9_Lapatinib_30min_R1 4 STVTGERQSGDGQESTEPVENK 22 1 O15234;J3KSY7 O15234 CASC3 Protein CASC3 1 S(0.001)T(0.001)VT(0.01)GERQS(0.976)GDGQES(0.009)T(0.003)EPVENK;STVTGERQS(1)GDGQESTEPVENK;S(0.002)T(0.002)VT(0.02)GERQS(0.972)GDGQES(0.002)T(0.001)EPVENK;STVT(0.001)GERQS(0.915)GDGQES(0.062)T(0.023)EPVENK 162.91 1.7452000000000003e-07 165608000.0 97078.0 92085.0 124620.0 100217.0 107391.0 96231.0 87649.0 87855.0 108386.0 82850.0 True False 95693.64991807532 91871.78284018552 114374.22464711146 107587.29249411185 101074.47251882954 92115.4244554174 92187.03635014927 91937.06403044595 96178.42732482142 97170.51210931444 0.9848013336640884 0.9454697813759798 1.177046638577383 1.1072010444184837 1.040176390190506 0.9479771430224614 0.9487141144881599 0.9461416023723227 0.9897902690542892 1.0 16.568230951734172 -6.691205573706671 5.368672542889236 0.9621109975628379 1.0565846661858436 0.32095910337753963 0.061243036276068724 0.25599147670252276 13.512848283830587 0.022449275849280567 0.02218572011037415 2.0360780700729364e-07 6.691205573706671 0.09447366862300566 SVAAEGALLPQT(ph)PPSPR ddPTM_PC-9_AZD4547_30min_R2 1 SVAAEGALLPQTPPSPR 17 0 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 SVAAEGALLPQT(0.943)PPS(0.057)PR 87.15700000000001 0.0071960999999999995 44004000.0 31566.0 26927.0 30174.0 46864.0 44636.0 35322.0 30645.0 30296.0 35002.0 38537.0 True False 41603.33138641213 35630.62616381552 29773.873044658634 36060.228841582364 38439.06187344375 33113.309756193084 33372.34563276866 25614.44933282189 36852.134262000756 37187.83135974991 1.1187350771801476 0.9581259476824502 0.8006348301580247 0.9696781856608073 1.0336462350167617 0.8904340087987259 0.897399617362175 0.6887857773966777 0.990972931588786 1.0 15.182542997954888 -6.932000418770428 8.804470246804005 0.8719587560087868 0.9650319161685742 0.10745655043211 0.10963120359401121 0.6123693410829794 72.47185627650812 0.03898804782807435 0.03437402018761884 1.1694982633253127e-07 6.932000418770428 0.0930731601597874 SVAAEGALLPQT(ph)PPSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SVAAEGALLPQTPPSPR 17 0 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 S(0.009)VAAEGALLPQT(0.964)PPS(0.027)PR;SVAAEGALLPQT(0.996)PPS(0.004)PR;SVAAEGALLPQT(0.967)PPS(0.033)PR 137.52 7.2952e-08 49078000.0 44909.0 41420.0 48877.0 54317.0 62061.0 54685.0 50454.0 48046.4 46510.0 36607.3 True False 52511.20670681865 45531.90386475634 50042.41304705474 51273.79458808997 49900.59255861617 51817.2223325594 45674.631864672665 46785.232909368766 47190.12076172467 43243.91370677264 1.2143028279744859 1.0529089520781596 1.1572128597420948 1.1856881163847974 1.1539333117946027 1.1982546881376293 1.0562094859031999 1.0818917368721301 1.091254623291277 1.0 15.400209476855167 -8.100643916189403 0.76430472287137 1.0108384436187474 1.1550252095850349 0.4938328633003565 0.048831903626713045 0.5529054016706454 0.6722180828701442 0.046786688531662166 0.019370872264048985 7.931513792965135e-09 8.100643916189403 0.14418676596628743 SVAAEGALLPQTPPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 SVAAEGALLPQTPPSPR 17 0 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 SVAAEGALLPQTPPS(1)PR;SVAAEGALLPQT(0.002)PPS(0.998)PR;SVAAEGALLPQT(0.385)PPS(0.615)PR 161.55 2.9156e-05 64036000.0 195546.0 176084.0 224581.0 257485.0 248534.0 239391.0 217205.0 224032.0 200175.0 220374.0 True False 257725.56039052538 232999.7094897051 221602.9092013812 198125.8113535943 214029.34410911534 224421.8429263583 236535.82421816 189413.00214321236 210755.84183463818 212658.77333662487 1.2119206574306847 1.0956505853670182 1.0420586262415723 0.9316606516862305 1.006444929362594 1.0553142924938876 1.112278701258844 0.8906898087076992 0.9910517141045742 1.0 17.698180849683332 -4.897244888651251 1.701389058767421 1.0012794185236267 1.2546101120275637 0.5653566777004309 0.05780358616836788 0.5791167629729655 2.013122748184031 0.017134201784034277 0.2251383041876787 1.2669372676718185e-05 4.897244888651251 0.253330693503937 SVAAEGALLPQTPPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVAAEGALLPQTPPSPR 17 0 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 SVAAEGALLPQTPPS(1)PR;SVAAEGALLPQT(0.021)PPS(0.979)PR 176.85 4.4801e-06 26142000.0 80100.0 91683.0 99598.0 111692.0 123926.0 111013.0 115156.0 91119.0 121959.0 82891.0 True False 93659.34795288635 100784.6823281618 101972.79404751836 105434.25935034982 99643.58991023473 105191.28285278247 104247.59002275842 88727.22279856107 123742.41965123992 97918.48213520485 0.9565032658856218 1.0292712890401972 1.0414049709912307 1.0767554505672103 1.0176177953069971 1.0742740344722197 1.0646364991525747 0.9061335599141276 1.26372894016451 1.0 16.57929357408956 -4.587789501678931 1.6797946876664154 1.0529937827212976 0.880885314935111 0.11106108657456226 0.08443789949571018 3.8699994645109257 7.272096071432815 0.02157533797876507 1.2578127156960333 2.5835120904585828e-05 4.587789501678931 -0.1721084677861866 SVAAEGALLPQTPPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 SVAAEGALLPQTPPSPR 17 0 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 SVAAEGALLPQT(0.002)PPS(0.998)PR;SVAAEGALLPQT(0.03)PPS(0.97)PR;SVAAEGALLPQT(0.002)PPS(0.998)PR 175.77 5.2474e-06 79247100.0 427444.0 410298.0 388834.0 373241.0 418886.0 418990.0 378180.0 343422.0 405139.0 306393.0 True False 421348.5701763706 409347.98018963344 356865.56946264557 400690.3882354759 394247.94904156186 401070.7744133948 397760.3099510483 359378.6398436493 359507.97951719625 359352.6218069905 1.1725212078810945 1.139126182331002 0.993079075555818 1.1150339914611451 1.0971060877727887 1.1160925232620433 1.1068802224147587 1.000072402523538 1.0004323266362287 1.0 18.45504068631807 -7.76268673708905 24.97248492313797 1.000189242131 1.1030752276512406 0.556674439335225 0.04310945255808467 26.284325262760444 526177.5071353269 0.02299148515100314 0.012006780196013962 1.7270832129818333e-08 7.76268673708905 0.10288598552024064 SVAEGLS(ph)GSLVQEPFQLATEKR ddPTM_PC-9_AZD4547_30min_R2 1 SVAEGLSGSLVQEPFQLATEKR 22 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 SVAEGLS(0.552)GS(0.448)LVQEPFQLATEKR 75.226 0.00040963 5622100.0 7706.9 7220.6 7929.1 14824.0 9920.7 10719.0 6495.7 14873.0 7500.2 11122.0 True False 10157.533886521562 9554.5177434711 7823.954953218098 11406.555828516925 8543.382048747058 10048.73923550857 7073.8047161617005 12574.719597539612 7896.645260038231 10732.622165273333 0.9464167963899319 0.8902314454324006 0.7289882036967097 1.0627930111454202 0.7960200142319536 0.9362799771357323 0.6590937990018721 1.1716353565698607 0.7357610412848371 1.0 13.389714974066463 -10.998194263198052 3.4571544959681026 1.0017919259446384 0.8831382571566856 0.05343405039003912 0.1502174179539314 31022818.62451126 24678374.947906308 389483.2341096487 0.03328770523110241 1.00416651854544e-11 10.998194263198052 -0.1186536687879528 SVAEGLSGS(ph)LVQEPFQLATEKR ddPTM_PC-9_AZD4547_30min_R2 1 SVAEGLSGSLVQEPFQLATEKR 22 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 SVAEGLS(0.429)GS(0.571)LVQEPFQLATEKR 88.471 9.7698e-05 4536100.0 15385.0 10743.0 17749.0 27611.0 21666.0 14285.0 14918.0 19250.0 10801.0 19266.0 True False 20277.109972120325 14215.464659184836 17513.636663009416 21245.71053569757 18658.049882382667 13391.75669178467 16245.673100004662 16275.35482099358 11371.918809321476 18591.503204114015 1.0906654372968245 0.7646215856305353 0.9420237014043016 1.1427645361670498 1.0035794135384344 0.7203159714821381 0.8738224618873068 0.875418982656125 0.6116729069441272 1.0 14.182355802708692 -6.746136297525634 24.977945433884837 0.8120582721443632 0.9822430281614043 0.293086159580063 0.13367010392160467 323.1024486498102 527372.2032221276 0.04430828069480999 0.04414973663205646 1.7941704620176175e-07 6.746136297525634 0.17018475601704108 SVAEGLSGS(ph)LVQEPFQLATEKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVAEGLSGSLVQEPFQLATEKR 22 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 S(0.001)VAEGLS(0.228)GS(0.772)LVQEPFQLATEKR 89.979 0.00068632 0.0 1885.9 1145.1 4177.5 1053.5 5047.7 3872.1 4343.7 4198.5 3628.7 1664.6 True False 2205.1456217771342 1258.777960297742 4277.107443256971 994.4758104930826 4058.639420217638 3669.0402595575256 3932.233290335326 4088.2938236784635 3681.7628726740527 1966.378803033649 1.1214246300738828 0.6401502896368445 2.175118769922878 0.5057396921482503 2.0640170723749334 1.8658868036499783 1.999733359751863 2.0790977899940795 1.8723568759966183 1.0 10.941325553754695 -6.2878088230690095 24.80584078315591 1.8793997277012153 1.1530405126273844 0.3079799845376361 0.5088927067668347 777.5236014117017 731417.2347951689 0.14928828323362758 0.16933064308494278 5.154554987514177e-07 6.2878088230690095 -0.7263592150738309 SVAPLPPQRS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 SVAPLPPQRSPR 12 1 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 SVAPLPPQRS(1)PR;SVAPLPPQRS(1)PR;SVAPLPPQRS(1)PR;SVAPLPPQRS(1)PR 103.3 0.0010095 49396100.0 175150.4 167639.0 278952.0 492635.0 394752.0 332814.0 300565.0 358867.0 290572.0 359808.0 True False 230844.58384536003 221825.0283906808 275252.91421600117 379065.6118848784 339947.49871551315 312003.08796777227 327314.7027284418 303412.3510932724 305931.04270550475 347211.231437032 0.6648534463875041 0.6388763044115684 0.7927534863339214 1.091743519689752 0.97907978756489 0.8985973370632602 0.9426961834551182 0.8738552316914244 0.8811092931508077 1.0 18.40545409064211 -5.5240929589889864 5.161264008973209 0.946304208557763 0.6632138319196228 0.7952811073841062 0.06158687184257276 0.07769273786305388 6.327027015006083 0.018027020979716847 0.034548147605697875 2.991624222926178e-06 5.5240929589889864 -0.2830903766381402 SVAPLPPQRS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SVAPLPPQRSPR 12 1 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 SVAPLPPQRS(1)PR;SVAPLPPQRS(1)PR;SVAPLPPQRS(1)PR;SVAPLPPQRS(1)PR 103.21 0.0010218 38227500.0 71155.0 72369.0 89109.0 132827.0 143441.0 149248.0 130652.0 163499.0 146578.0 100365.0 True False 83200.13612468944 79553.31604994103 91233.69650776421 125385.13382094432 115334.76574983445 141421.17214391197 118275.69672143343 159207.32449150973 148721.42595166762 118560.38001109696 0.7017532848401979 0.6709941047970244 0.7695125175815476 1.0575635284671707 0.9727934891828063 1.1928198284340459 0.9975988328509331 1.3428375016730574 1.2543939715590289 1.0 16.855262451343386 -5.833264168680409 0.8610671712505787 1.180078190649741 0.619944792110444 0.7363609727963013 0.11174706258242567 0.3721589689667036 0.5184790005982718 0.04961563022671036 0.14760038064890657 1.468033044276999e-06 5.833264168680409 -0.5601333985392971 SVAPLPPQRS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 SVAPLPPQRSPR 12 1 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 SVAPLPPQRS(1)PR;SVAPLPPQRS(1)PR;SVAPLPPQRS(1)PR;SVAPLPPQRS(1)PR 131.42 5.5271999999999995e-05 40252500.0 669501.0 574809.5 694770.8 632733.3 648140.7 595067.7 558697.6 520511.2 701381.0 460863.3 True False 659953.7929685519 573478.5639189408 637649.426716844 679266.6176184133 610018.3383196434 569618.0416415606 587624.2279996481 544696.0505715584 622384.0859106403 540522.9073432528 1.2209543462502244 1.0609699535911805 1.1796899225806763 1.256684237412075 1.1285707414658346 1.053827754389383 1.0871402858537578 1.00772056682818 1.1514481208016638 1.0 19.04399623506132 -6.597888800791207 4.462678345355586 1.0628621535874816 1.1734928857441709 0.4570325514397239 0.06128319221113427 0.210413031495893 7.990223800074485 0.020484745666774707 0.020607478105357593 2.524126981457269e-07 6.597888800791207 0.11063073215668928 SVAS(ph)SQPAKPTK ddPTM_PC-9_Lapatinib_30min_R1 1 SVASSQPAKPTK 12 1 A0A087X0K9;G5E9E7;Q07157-2;H0YKB1;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 SVAS(0.761)S(0.237)QPAKPT(0.002)K 116.19 0.0033218 12340000.0 32741.0 31213.0 26577.0 26616.0 29119.0 33007.0 25463.0 30689.0 28585.0 28079.0 True False 32274.10733603597 31140.72821622102 24391.94165018679 28573.429428373176 27406.277670156676 31595.36755307505 26781.34954858415 32114.922975702593 25365.456286605484 32932.41773708433 0.9800102620371217 0.9455949594965287 0.740666593170281 0.8676383755510725 0.8321975595279537 0.9594001814660676 0.8132214817142434 0.9751765944453821 0.770227576034969 1.0 15.007220810986523 -7.7510772510132995 24.99141014132687 0.9045265848231986 0.8754494774752164 0.03311914357905932 0.08889003789057831 1078.107037532755 2600196.118827936 0.04166297745067512 0.023711256953707256 1.7738739213979594e-08 7.7510772510132995 -0.02907710734798219 SVAVS(ph)DEEEVEEEAER ddPTM_PC-9_Lapatinib_30min_R1 1 SVAVSDEEEVEEEAER 16 0 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 S(0.05)VAVS(0.95)DEEEVEEEAER 188.04 4.3845e-08 8299200.0 14687.0 15752.0 16674.0 13291.0 14356.0 12709.0 7241.5 9904.2 13447.0 8742.2 True False 14477.56068673407 15715.527211799987 15303.128083501322 14268.464477476253 13511.60830498195 12165.465696125986 7616.4294370683765 10364.385289059717 11932.457256812446 10253.277621750725 1.4119934347649175 1.5327320483805054 1.492510848534729 1.3916003256566405 1.3177843030719452 1.1864952988612005 0.7428287536964094 1.0108363073163351 1.163770035008084 1.0 13.323797543209732 -6.762085396764968 2.001815553728583 0.9802680637570507 1.4610266618502095 0.7941076360930428 0.10850350083497184 0.14496499824517892 1.196666482957657 0.04534743076264373 0.04162428453743328 1.7294762531240384e-07 6.762085396764968 0.4807585980931588 SVAVS(ph)DEEEVEEEAERR ddPTM_PC-9_AZD4547_30min_R2 1 SVAVSDEEEVEEEAERR 17 1 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 S(0.066)VAVS(0.934)DEEEVEEEAERR 66.777 0.0090193 5490700.0 11716.0 9172.1 8234.4 14265.0 10391.0 14490.0 9180.5 10903.0 11406.0 11713.0 True False 15441.444292061213 12136.801954808636 8125.206475738615 10976.42464205301 8948.38901171597 13583.938009377654 9997.546715014934 9218.191876015222 12008.89787418949 11302.931435159728 1.366145090823777 1.07377471273116 0.7188583353220875 0.9711130873455481 0.7916874540953557 1.2018066363848285 0.8845091888212143 0.8155576213919549 1.0624587031319797 1.0 13.464409366216396 -4.860567954847311 3.5885344228433893 0.9269338791375826 1.3823468675647503 0.49270730843898347 0.13390517819302689 0.19910508949738376 4.30069171565185 0.03289079994880955 0.21234912756857835 1.3785802271368197e-05 4.860567954847311 0.4554129884271677 SVCPGGS(ph)SPGSSSGGGR ddPTM_PC-9_AZD4547_30min_R2 3 SVCPGGSSPGSSSGGGR 17 0 Q53LP3 Q53LP3 SOWAHC Ankyrin repeat domain-containing protein SOWAHC 1 S(0.039)VCPGGS(0.368)S(0.368)PGS(0.067)S(0.067)S(0.09)GGGR;SVCPGGS(0.5)S(0.5)PGSSSGGGR;S(0.03)VCPGGS(0.443)S(0.443)PGS(0.062)S(0.019)S(0.003)GGGR 210.02 1.1470999999999999e-17 26509000.0 37138.3 36294.9 55733.7 72588.1 58867.2 56378.2 44917.4 62006.6 43080.7 52184.9 True False 48947.506875371895 48026.516639546484 54994.63472224731 55854.0350199656 50694.50540183685 52852.862241566254 48914.96158346625 52424.904739917925 45357.857851007815 50357.922534847334 0.9719921794132901 0.9537032947757618 1.0920751284803578 1.1091409694535155 1.0066838116039556 1.0495441348874637 0.9713458999349592 1.0410458196253083 0.9007094726677911 1.0 15.619931146909503 -7.843180787508467 1.4935356868135896 0.9616009314611069 1.0304683436497417 0.16775511783974906 0.05568231019062905 0.7751707158538396 3.176028932522685 0.04845518963398766 0.017782791066966768 1.4348919941496628e-08 7.843180787508467 0.06886741218863479 SVCPGGS(ph)SPGSSSGGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVCPGGSSPGSSSGGGR 17 0 Q53LP3 Q53LP3 SOWAHC Ankyrin repeat domain-containing protein SOWAHC 1 SVCPGGS(0.476)S(0.476)PGS(0.041)S(0.006)S(0.001)GGGR;S(0.002)VCPGGS(0.491)S(0.491)PGS(0.008)S(0.002)S(0.005)GGGR 225.29 5.959e-29 17436600.0 28696.0 30941.0 36993.0 34169.0 37392.0 35926.0 39017.0 35996.0 34649.0 25834.0 True False 33553.66602816515 34012.61799805473 37875.053416733754 32254.621707392653 30065.306020717926 34041.97731589152 35321.02730138212 35051.1431409146 35155.676075532094 30517.499698168536 1.0994893539780661 1.1145283307759302 1.2410929398323798 1.0569221602819698 0.9851824794978945 1.1154903793751656 1.157402397009014 1.148558810111765 1.1519841541160698 1.0 14.897349146413342 -10.64498393807281 4.1430495746025695 0.9999773020697177 1.1185626611940158 0.23914252224945465 0.06365397822795171 9226650.642528933 11853291.966844592 1751.2227981864658 0.016604908941293097 2.2647280646430344e-11 10.64498393807281 0.11858535912429813 SVCPGGS(ph)SPGSSSGGGR ddPTM_PC-9_Lapatinib_30min_R1 2 SVCPGGSSPGSSSGGGR 17 0 Q53LP3 Q53LP3 SOWAHC Ankyrin repeat domain-containing protein SOWAHC 1 S(0.002)VCPGGS(0.499)S(0.499)PGSSSGGGR;S(0.001)VCPGGS(0.499)S(0.499)PGSSSGGGR 236.31 1.2857999999999999e-112 15371000.0 45424.0 41685.0 44187.0 38104.0 45138.0 41478.0 33702.0 35114.0 44717.0 34262.0 True False 44776.24543025858 41588.48094361877 40554.11542675257 40906.29527121778 42483.0715847224 39704.0826299405 35446.924654847535 36745.524629959305 39680.500569114476 40184.141048754704 1.114276534514757 1.03494761510916 1.0092069748996 1.0179711250163814 1.0572098961423224 0.9880535353926875 0.8821122893193215 0.9144285200815071 0.9874666854511294 1.0 15.29433862362718 -6.9787039455392375 4.871317744892302 0.9380050804149638 1.0415383190416911 0.5639166358924768 0.04149166756612294 0.1380148061067427 8.630557277691011 0.015487575827507736 0.013137108423461438 1.0502581357653962e-07 6.9787039455392375 0.10353323862672736 SVCPVTSGFSSPS(ph)PSAAAAAQEVR ddPTM_PC-9_Lapatinib_30min_R1 1 SVCPVTSGFSSPSPSAAAAAQEVR 24 0 K4DI93 K4DI93 CUL4B 1 SVCPVTSGFS(0.001)S(0.004)PS(0.888)PS(0.107)AAAAAQEVR 60.527 0.019865 0.0 6922.5 5133.5 6865.2 3411.9 6240.0 6507.2 5657.5 5424.7 6359.6 4531.7 True False 6823.783880568981 5121.613696151301 6300.769756438358 3662.822507764746 5872.975468312018 6228.902225024084 5950.4176676398965 5676.751365840983 5643.314878443106 5314.998306889315 1.2838731993054397 0.9636153015350262 1.1854697579623465 0.6891483865605349 1.1049816254314608 1.1719481108677239 1.1195521285353842 1.068062685642395 1.0617717170536491 1.0 12.375853516843156 SVDALDDLT(ph)PPSTAESGSR ddPTM_PC-9_AZD4547_30min_R2 1 SVDALDDLTPPSTAESGSR 19 0 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 1 SVDALDDLT(0.978)PPS(0.011)T(0.011)AESGSR 110.61 0.0011045 0.0 3468.3 7121.5 4867.3 4070.8 4399.4 5158.8 5388.6 6163.4 4964.9 2930.0 True False 4571.147254878451 9423.385606477215 4802.756421762676 3132.3399532330477 3788.6192491717093 4836.219420481533 5868.174960898584 5210.988150842172 5227.334477955758 2827.421591822591 1.6167193700787414 3.332854793827469 1.6986346980065183 1.1078432598422305 1.339955548238393 1.710469862177167 2.0754509967209684 1.8430177395239826 1.8487990942256878 1.0 11.465271301571375 -5.486937025845008 24.861089344834117 1.5981531050185562 2.4850270073206815 0.3408760631192722 0.5000837330501735 580.0200089976767 401202.0397910503 0.12763401006734476 0.265526098190855 3.2588395184106132e-06 5.486937025845008 0.8868739023021253 SVDALDDLT(ph)PPSTAESGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SVDALDDLTPPSTAESGSR 19 0 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 1 SVDALDDLT(0.994)PPS(0.002)T(0.003)AESGS(0.001)R;S(0.001)VDALDDLT(0.999)PPSTAESGSR;S(0.004)VDALDDLT(0.967)PPS(0.008)T(0.008)AES(0.004)GS(0.009)R 124.98 6.8602e-05 5654400.0 41184.2 48378.6 48511.6 23970.6 61134.2 22431.0 20330.2 17469.3 19764.2 21500.9 True False 48155.871634972085 53181.30768497105 49668.30052526751 22627.604995733753 49155.392365526706 21254.678872481287 18404.376278098232 17010.74938525334 20053.21403480711 25398.84296896924 1.8959868248252882 2.0938476508534163 1.9555339818411892 0.890891172616752 1.9353398273134637 0.8368365007196966 0.724614751175224 0.6697450512228467 0.7895325806497134 1.0 14.632475156824434 -6.224694079742082 0.728074905657813 0.7270876187612066 2.0959935835258636 0.6595186950853482 0.333938797009946 0.458837655825145 0.5179871472455007 0.19644946347699566 0.3688768940864179 5.960818801814695e-07 6.224694079742082 1.3689059647646569 SVDALDDLT(ph)PPSTAESGSR ddPTM_PC-9_Lapatinib_30min_R1 1 SVDALDDLTPPSTAESGSR 19 0 S4R3V8;Q86X29-6;Q86X29-5;Q86X29-2;Q86X29-3;Q86X29-4;Q86X29 S4R3V8 LSR Lipolysis-stimulated lipoprotein receptor 1 S(0.175)VDALDDLT(0.703)PPS(0.025)T(0.073)AES(0.013)GS(0.011)R 104.16 0.0006468 1437500.0 16018.0 23838.0 8679.5 5601.8 9138.7 5796.2 4346.1 4614.6 9497.4 1877.3 True False 15789.58038265855 23782.804575602342 7965.905013838887 6013.775059056997 8601.179633375486 5548.310037602133 4571.119792369378 4829.011162425536 8427.702799944267 2201.788803654986 7.171251101126378 10.8015830292727 3.6179242080872713 2.731313307195533 3.9064507999574993 2.519910187749114 2.07609366746769 2.1932217814939112 3.8276617566381557 1.0 11.104460376392609 -5.355178455795391 5.336752094551538 2.7297388834309455 8.951122388685171 0.8261068853475343 1.1516171217614526 0.07329734293545685 3.2216115813595643 0.28673365083717206 0.6166791722511046 4.413890390672346e-06 5.355178455795391 6.2213835052542255 SVDEALR ddPTM_PC-9_Lapatinib_30min_R1 1 SVDEALR 7 0 P32119 P32119 PRDX2 Peroxiredoxin-2 0 124.59 0.021338 3032200.0 51791.0 44213.0 45577.0 39789.0 37895.0 45128.0 38405.0 39115.0 46230.0 37772.0 False True 51052.45084269382 44110.62751493863 41829.834992307726 42715.21579221297 35666.09060443654 43197.980638506095 40393.42298289178 40932.42569632792 41023.09057651815 44300.83987197369 1.1524036788068084 0.9957063487377494 0.9442221662883369 0.9642078099570334 0.8050883619251697 0.9751052296828959 0.911798130681629 0.923965004153866 0.9260115766444158 1.0 15.435046429743865 -4.445015751727447 1.2906888631344666 0.9230970847313206 1.4430422579794622 0.6481128246940552 0.04933329653184297 1.6950648723283375 1.4005672882075781 0.013881148850758215 1.4359644128466424 3.589089168927697e-05 4.445015751727447 0.5199451732481416 SVDETLR ddPTM_PC-9_AZD4547_30min_R2 1 SVDETLR 7 0 A0A0A0MSI0;Q06830;A0A0A0MRQ5;H7C3T4;Q13162 A0A0A0MSI0;Q13162 PRDX1;PRDX4 Peroxiredoxin-1;Peroxiredoxin-4 0 125.25 0.021208 48217000.0 87657.0 83170.0 110060.0 154870.0 119420.0 111730.0 98207.0 129100.0 87674.0 96912.0 False True 115530.1026211342 110053.07602200515 108600.5324880736 119167.1142176481 102840.59433924781 104743.50543738878 106947.23274783214 109150.56142287125 92308.26864998156 93519.14037771724 1.2353631797139732 1.176797344131998 1.1612652987339669 1.2742537381795906 1.0996742904594918 1.1200221154122796 1.1435865675826336 1.1671467571453267 0.9870521507913241 1.0 16.512974048314398 -7.937646730894885 0.4270875762965305 0.9850687122066247 1.2124847807545236 0.6211276452005569 0.05315352651803695 0.7137221529817457 0.35363726295710934 0.0626097818274114 0.0460124909408974 1.1543918955209514e-08 7.937646730894885 0.22741606854789886 SVDETLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVDETLR 7 0 A0A0A0MSI0;Q06830;A0A0A0MRQ5;H7C3T4;Q13162 A0A0A0MSI0;Q13162 PRDX1;PRDX4 Peroxiredoxin-1;Peroxiredoxin-4 0 ; 120.62 0.027533 47319000.0 141438.0 134792.0 152975.0 156751.0 170316.0 143231.0 172737.0 130240.0 129881.0 112715.0 False True 165380.65987216387 148173.25895070581 156622.50416091835 147968.74966359904 136943.80242363614 135719.71421623512 156374.1008524196 126821.33800068665 131780.2639142889 133149.33724855082 1.2420689677444403 1.1128351219211083 1.1762920296670347 1.111299182716807 1.0284978149609725 1.0193044668550333 1.1744264303810612 0.9524744217385653 0.9897177608048754 1.0 17.022685721981894 -1.5228787452835604 0.22210602023829099 0.9777731444056452 2.306501033884639 0.5880761823545325 0.05870323334547919 37.40764624237153 0.4807346628062395 0.09212484983786902 17.868493359260267 0.029999999999777375 1.5228787452835604 1.3287278894789938 SVDETLR ddPTM_PC-9_Lapatinib_30min_R1 3 SVDETLR 7 0 A0A0A0MSI0;Q06830;A0A0A0MRQ5;H7C3T4;Q13162 A0A0A0MSI0;Q13162 PRDX1;PRDX4 Peroxiredoxin-1;Peroxiredoxin-4 0 ;; 127.12 0.02084 97136000.0 286102.0 223123.0 267817.0 256590.0 244992.0 253615.0 224711.0 236738.0 243658.0 231007.0 False True 282022.1330153185 222606.37240213662 245798.12006351605 275460.48455914744 230582.05223280442 242768.4776554404 236345.4360606328 247737.71173455918 216214.67020751172 270936.2521525211 1.0409169344254334 0.8216189994272984 0.9072175395898893 1.0166985125492896 0.8510564769420386 0.8960354169170985 0.8723285798150935 0.9143763884173665 0.798027833077855 1.0 18.0475939181853 -6.329025549189064 24.9999029136943 0.8839107457870676 0.934874165553739 0.11895131276954107 0.07394137149138456 431.4473905246267 159589.38636330102 0.022065604527916283 0.025020047330002945 4.6878580304877684e-07 6.329025549189064 0.0509634197666714 SVDISLGDS(ph)PRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SVDISLGDSPRR 12 1 H0YDE2;A0A1B0GTN9;E9PKC0;Q6IQ23-3;Q6IQ23;Q6IQ23-2 H0YDE2 PLEKHA7 Pleckstrin homology domain-containing family A member 7 1 SVDISLGDS(1)PRR;SVDISLGDS(1)PRR;SVDISLGDS(1)PRR 85.163 0.0044995 6277600.0 26527.9 33637.8 37238.9 38183.4 45235.0 38771.3 28587.6 33417.3 34820.2 26752.3 True False 31018.549520092063 36977.1384795244 38126.81660531471 36044.107890253064 36371.526472164536 36738.06477502716 25879.57557169928 32540.131283556122 35329.37955165353 31602.280218909724 0.9815288423881395 1.1700781786435317 1.2064577727053039 1.1405540246012218 1.1509146245213362 1.162513100970618 0.8189148185647005 1.0296766897245984 1.11793767117202 1.0 14.947741037376824 SVDISLGDS(ph)PRR ddPTM_PC-9_Lapatinib_30min_R1 2 SVDISLGDSPRR 12 1 H0YDE2;A0A1B0GTN9;E9PKC0;Q6IQ23-3;Q6IQ23;Q6IQ23-2 H0YDE2 PLEKHA7 Pleckstrin homology domain-containing family A member 7 1 SVDISLGDS(1)PRR;SVDISLGDS(1)PRR 127.18 0.00011089 15475400.0 46678.0 37220.0 49521.0 37587.0 40280.0 41643.0 30702.0 33050.0 40680.0 29778.0 True False 46012.36316030319 37133.81937679 45449.574536588036 40351.27336655633 37910.80959352695 39862.025964574306 32291.59933396024 34585.62365495686 36098.19002060908 34925.08762330911 1.3174587750953672 1.0632419817325462 1.3013446101207444 1.1553664174524723 1.085489319380409 1.1413579371514666 0.9245960864077755 0.99028022572159 1.0335891039115686 1.0 15.09197611475627 -6.693718931080842 1.127148892204473 0.9883139972326359 1.2116997869923603 0.5951885916071942 0.07827783180031021 0.3354113839114061 0.9068016898515217 0.038503038477545055 0.037153077605616994 2.024328870315262e-07 6.693718931080842 0.22338578975972434 SVDQGGGGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 SVDQGGGGSPR 11 0 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 SVDQGGGGS(1)PR;S(0.004)VDQGGGGS(0.996)PR 96.23 0.0058909 176733000.0 33918.0 22661.3 31667.0 42155.0 34132.0 25494.4 27123.8 31364.0 29557.0 34529.0 True False 44703.21846177298 29986.122059125515 31247.07488914976 32436.816038257617 29393.36096120582 23900.231137769326 29537.765654236933 26517.414473020395 31119.32267818858 33320.15021980963 1.3416271585473178 0.8999395819439627 0.9377831337198662 0.9734894898214821 0.8821497132306073 0.717290617842415 0.8864835680325361 0.7958371825483295 0.9339490510366125 1.0 15.024107284481177 -4.7599552534210074 5.596569519900602 0.8822172595156661 1.3633511486546315 0.7433934356528684 0.07915472633300222 0.0762496582926344 7.838928809563664 0.020422193255794033 0.14202979385737352 1.737979888468952e-05 4.7599552534210074 0.4811338891389654 SVDQGGGGS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SVDQGGGGSPR 11 0 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 SVDQGGGGS(1)PR;S(0.001)VDQGGGGS(0.999)PR;SVDQGGGGS(1)PR;S(0.001)VDQGGGGS(0.999)PR 110.15 0.0019722000000000003 188888000.0 38672.2 56697.0 51542.5 46499.4 68644.0 66244.0 52431.0 50762.0 62532.0 57720.0 True False 45218.639649233635 62325.50346258068 52771.468676019766 43894.18937108882 55193.70096507706 62770.04802410283 47464.356112432164 49429.55128678482 63446.41220107865 68184.17908873128 0.6631837510339237 0.9140757327513406 0.7739547411335079 0.6437591528962642 0.8094795846005699 0.9205954938962777 0.6961197853634721 0.7249416499164685 0.9305151583406592 1.0 16.057149406217356 -8.42165172012299 4.182432868291814 0.9974585193832262 0.7736966611040922 0.44233000943928935 0.0897143238646778 0.2002004504052063 5.671735072183855 0.08690598807849231 0.02279614064948109 3.787461962207554e-09 8.42165172012299 -0.22376185827913397 SVDQGGGGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 SVDQGGGGSPR 11 0 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 SVDQGGGGS(1)PR;SVDQGGGGS(1)PR 101.38 0.0037575000000000004 152420000.0 25066.0 32791.0 27463.0 26463.1 29139.0 23141.9 28288.0 29223.0 31802.0 20917.7 True False 24708.554243458577 32715.07445417302 25205.098150245693 28409.28465231375 27425.1013094782 22152.17488340374 29752.614225752975 30580.807263806495 28220.123870093663 24533.29657391674 1.0071436657121802 1.3334968806823524 1.0273832574560402 1.1579888812218522 1.1178726522482902 0.9029432639295382 1.212744244790376 1.2465021637703322 1.1502785116981251 1.0 14.582453483452928 -10.274263146688321 15.000739740656522 1.0000091025589295 1.1314115267242955 0.09524052711476017 0.11849350418440105 0.0 0.0 0.11340594935307187 0.027504982809186014 5.31785943143531e-11 10.274263146688321 0.13140242416536596 SVEAAAELS(ph)AK ddPTM_PC-9_Lapatinib_30min_R1 1 SVEAAAELSAK 11 0 P20962;F5H7R9;F5GXR3 P20962 PTMS Parathymosin 1 SVEAAAELS(1)AK 120.53 0.0018437999999999998 0.0 19663.0 19550.0 20610.0 18850.0 19262.0 14188.0 21178.0 13318.0 19091.0 17489.0 True False 19382.60201424743 19504.733176148413 18915.525356900696 20236.291881756635 18129.04703054905 13581.21231384338 22274.49321525015 13936.802899749342 16940.770542857626 20511.950347372338 0.9449419331658249 0.9508960798867694 0.922170980163466 0.9865610797146349 0.8838285352456233 0.6621121874733471 1.085927609906856 0.6794479639297051 0.8258975990075856 1.0 14.324177054336838 -6.517419312482553 24.73832081257301 0.8373040341922238 0.9473229450333374 0.12869248581310622 0.12091946807306891 395.77715461600957 1793394.7340300677 0.037451807758951156 0.038563892073679495 3.037950459953349e-07 6.517419312482553 0.11001891084111359 SVEAAAELSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVEAAAELSAK 11 0 P20962;F5H7R9;F5GXR3 P20962 PTMS Parathymosin 0 103.88 0.010131 0.0 15919.0 14681.0 15493.0 20020.0 24578.0 20273.0 19853.0 20083.0 19060.0 17329.0 False True 18613.77228541822 16138.43265665109 15862.411877529692 18898.34430571574 19762.11733464928 19209.848191423174 17972.380116727047 19555.842529697416 19338.716442022625 20470.61052371148 0.9092924836734865 0.7883708518589444 0.7748870928473761 0.9231939752761865 0.96538973821804 0.9384111025497779 0.8779601417314502 0.9553131064188598 0.9447063837994593 1.0 14.321266510068863 -5.860042893448107 6.297625103060097 0.940938346480002 0.821169442405784 0.6083196566532247 0.04400210587917217 0.1393706767758475 7.530413508261346 0.012438183378330378 0.018668514038783543 1.380247936559472e-06 5.860042893448107 -0.11976890407421792 SVEAAAELSAK ddPTM_PC-9_Lapatinib_30min_R1 2 SVEAAAELSAK 11 0 P20962;F5H7R9;F5GXR3 P20962 PTMS Parathymosin 0 ; 192.1 0.001334 14109500.0 65585.0 75183.0 79391.0 67713.0 64969.0 67682.0 68956.0 65542.0 70420.0 66018.0 False True 64649.74587318403 75008.91838272987 72863.77843812236 72692.8399039464 61147.65115396849 64787.39863444793 72526.2042757008 68587.32059283469 62488.55804452539 77429.12333654435 0.8349538660302923 0.9687429632478841 0.9410384012927695 0.9388307237831975 0.7897241828270647 0.8367316565480228 0.9366786184633256 0.8858077895925682 0.8070420450573869 1.0 16.240588687398215 SVEDEMDS(ph)PGEEPFYTGQGR ddPTM_PC-9_AZD4547_30min_R2 2 SVEDEMDSPGEEPFYTGQGR 20 0 A0A590UJA3;S4R3W2;A0A590UJU2;A0A590UK38;B1AKN5;A0A590UK09;B1AKN8;Q12857-2;Q12857-3;Q12857;Q12857-4;A0A590UK73;B1AKN7 A0A590UJA3 NFIA Nuclear factor 1;Nuclear factor 1 A-type 1 SVEDEMDS(1)PGEEPFYTGQGR;SVEDEMDS(1)PGEEPFYTGQGR 180.32 8.6771e-10 13590000.0 27634.0 28799.4 32860.0 43907.0 42426.0 39776.0 30827.0 44679.0 38778.0 32531.0 True False 36421.03717709284 38108.242847037865 32424.254929657425 33784.91950638776 36535.88222606697 37288.80043209147 33570.54328018793 37774.887171281654 40827.72591314396 31392.09959166578 1.160197554507064 1.2139437419838952 1.0328794617568577 1.0762236341578517 1.1638559606177727 1.187840282017683 1.0693946475979101 1.2033246473679775 1.300573279398719 1.0 14.938113903187078 -6.38525711688291 16.740188601627334 1.1617942557113936 1.1209997480211011 0.029494283736241522 0.087365965067171 6.396331762489822 837.983043232651 0.027486429904790024 0.03116639521083474 4.118536157666341e-07 6.38525711688291 -0.04079450769029247 SVEDEMDS(ph)PGEEPFYTGQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SVEDEMDSPGEEPFYTGQGR 20 0 A0A590UJA3;S4R3W2;A0A590UJU2;A0A590UK38;B1AKN5;A0A590UK09;B1AKN8;Q12857-2;Q12857-3;Q12857;Q12857-4;A0A590UK73;B1AKN7 A0A590UJA3 NFIA Nuclear factor 1;Nuclear factor 1 A-type 1 SVEDEMDS(1)PGEEPFYTGQGR;SVEDEMDS(1)PGEEPFYTGQGR;S(0.024)VEDEMDS(0.974)PGEEPFY(0.002)TGQGR 104.16 0.00014282 10833500.0 32118.9 40128.1 45927.6 42481.0 40350.0 32358.5 34095.8 32233.9 29977.9 25533.8 True False 37555.995392808516 44111.752570626 47022.688165392916 40100.92729526024 32443.707154898595 30661.563296116354 30865.998991784723 31387.794279640173 30416.270074885106 30162.8758145504 1.2451065881023093 1.4624518179843693 1.5589590480198654 1.3294795742226868 1.0756171710672209 1.0165331543527885 1.023310879955788 1.040610135207959 1.0084008654178946 1.0 14.880486365370848 -6.223824433620663 3.029458058069147 1.0228707593879527 1.4284945718941646 0.8611430153102012 0.07389649839156509 0.09071154571854263 1.6773521986592619 0.02391288737783 0.03067890382791105 5.972766907871449e-07 6.223824433620663 0.40562381250621193 SVEDEMDS(ph)PGEEPFYTGQGR ddPTM_PC-9_Lapatinib_30min_R1 2 SVEDEMDSPGEEPFYTGQGR 20 0 A0A590UJA3;S4R3W2;A0A590UJU2;A0A590UK38;B1AKN5;A0A590UK09;B1AKN8;Q12857-2;Q12857-3;Q12857;Q12857-4;A0A590UK73;B1AKN7 A0A590UJA3 NFIA Nuclear factor 1;Nuclear factor 1 A-type 1 SVEDEMDS(0.999)PGEEPFY(0.001)TGQGR;SVEDEMDS(1)PGEEPFYTGQGR 164.82 4.5395000000000004e-08 12527100.0 17567.7 23769.0 24653.0 21724.9 21855.0 23091.0 18232.2 18739.1 20974.8 16638.7 True False 17317.18137647838 23713.964340863018 22626.125503331998 23322.621618141908 20569.531868583188 22103.45175775004 19176.174105160262 19609.786996447878 18612.397149564204 19514.67712532586 0.8873926668253403 1.2151860975494893 1.1594414479944506 1.1951323339023712 1.0540544297239924 1.1326578254817503 0.9826539266834042 1.0048737609395846 0.9537640325808573 1.0 14.252271972813393 -7.265271705339602 23.411807080090743 0.9857290570269205 1.1161549453498285 0.31687520281285275 0.08716692010333037 161.06237858463118 983923.170305174 0.03479897857423254 0.024526199304873195 5.429105669795816e-08 7.265271705339602 0.13042588832290802 SVEDVRPHHT(ph)DANNQSACFEAPDQK ddPTM_PC-9_Lapatinib_30min_R1 1 SVEDVRPHHTDANNQSACFEAPDQK 25 1 E7EPN9;Q9Y520-2;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3 E7EPN9 PRRC2C Protein PRRC2C 1 S(0.338)VEDVRPHHT(0.55)DANNQS(0.112)ACFEAPDQK 50.426 0.014971 5090900.0 15819.0 10375.0 28888.0 17880.0 23182.0 25257.0 19126.0 23594.0 25813.0 16822.0 True False 15593.418159150688 10350.977324938105 26512.940150904764 19194.95484593149 21818.480337565587 24176.81698694265 20116.250695763272 24690.26337413169 22905.668117059544 19729.66028609397 0.7903541131998798 0.5246404233444288 1.343811285468095 0.9728983959982648 1.1058720738817727 1.2254046261497549 1.0195943774025233 1.2514287127150432 1.1609763059734035 1.0 14.268078494871594 -5.255972363369301 24.99329871079906 1.1362555561208016 0.6574972428757673 0.6951357633012135 0.12648676203988313 221.01430224143462 1010392.7085646087 0.03026842777697665 0.0754739608342533 5.546610080729949e-06 5.255972363369301 -0.4787583132450344 SVEEEEQVWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVEEEEQVWR 10 0 Q9P2E9;A0A087WVV2;Q9P2E9-3;F8W7S5;A0A087WU26 Q9P2E9 RRBP1 Ribosome-binding protein 1 0 95.573 0.027020999999999996 1965500.0 10164.0 13216.0 10166.0 13347.0 15033.0 11940.0 14515.0 11401.0 12473.0 11607.0 False True 11884.564451849403 14527.997138498802 10408.395994769691 12599.210861557835 12087.391565293457 11313.84538083129 13140.034120500331 11101.735830358017 12655.394028402323 13711.257219038554 0.8667742324421771 1.0595671065324466 0.759113174561212 0.9188953762798203 0.8815669761128613 0.8251501084176018 0.9583391158510935 0.8096803708811525 0.9229929703915022 1.0 13.74307324100317 -8.537142443478505 22.85618963370216 1.0000000051688998 0.8866426424960964 0.16484637704988803 0.07903941908259689 1367.549348062684 2191366.1246154173 0.07213638058785436 0.018625533417194712 2.903070325398454e-09 8.537142443478505 -0.11335736267280339 SVEST(ph)SPEPSK ddPTM_PC-9_Lapatinib_30min_R1 1 SVESTSPEPSK 11 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;P18583-8 P18583-10 SON Protein SON 1 SVES(0.001)T(0.5)S(0.5)PEPSK 176.32 0.0058042 68945000.0 96519.0 90393.0 97214.0 80222.0 90259.0 89394.0 86826.0 73166.0 92380.0 74253.0 True False 95142.62136058319 90183.7005622294 89221.44017689205 86121.79349274685 84950.14307602154 85570.82700759204 91321.42543711909 76565.5594656151 81975.19159547373 87087.53211409676 1.0924941728275541 1.0355523732613783 1.024503025989984 0.9889107131881443 0.9754570030153692 0.9825841303607316 1.048616526616868 0.8791793452741729 0.9412965278207086 1.0 16.41017856973201 -1.5228787453079466 0.3626646801004879 0.95632425022777 2.6961497709101487 0.48314103457174384 0.040513960639490455 55.96136980948366 0.7791110493791935 0.03386240542286507 67.37545688955312 0.029999999998092833 1.5228787453079466 1.7398255206823787 SVESTS(ph)PEPSK ddPTM_PC-9_AZD4547_30min_R2 3 SVESTSPEPSK 11 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;P18583-8 P18583-10 SON Protein SON 1 SVES(0.016)T(0.403)S(0.58)PEPSK;SVES(0.003)T(0.425)S(0.572)PEPSK;SVES(0.01)T(0.149)S(0.836)PEPS(0.005)K 105.36 0.0025681999999999996 75953000.0 126587.0 117769.0 164970.0 215281.0 197422.0 174739.0 149926.0 176302.0 139984.0 159744.0 True False 166839.03282683113 155835.5261516836 162782.39001051703 165651.29150829394 170013.36305177474 163812.5427067385 163269.12355485282 149058.5769169255 147383.26845699997 154151.41118228965 1.0823062309143436 1.0109250700754364 1.0559902680230473 1.074601200454826 1.102898518721491 1.0626730008525462 1.0591477710300112 0.9669621301141272 0.9560941889965178 1.0 17.233988571124016 -7.750911518800318 8.252836479410675 0.9709898829406002 1.063670917234246 0.7394479033132795 0.024383515278734277 0.06959026528615893 33.155838793406254 0.012776451308387475 0.006944221735387785 1.774550983080052e-08 7.750911518800318 0.09268103429364583 SVESTS(ph)PEPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SVESTSPEPSK 11 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;P18583-8 P18583-10 SON Protein SON 1 SVES(0.003)T(0.018)S(0.979)PEPSK;SVES(0.053)T(0.198)S(0.749)PEPSK;SVEST(0.085)S(0.915)PEPSK 160.86 7.726e-05 84008000.0 324948.0 327461.0 347193.0 408990.0 414530.0 385295.0 413770.0 354785.0 341848.0 297719.0 True False 379955.27838445106 359969.1639656443 355471.3978567844 386075.6162634702 333305.8222285035 365089.4519269171 374574.71016461804 345472.26967577945 346846.8802871216 351693.09795769205 1.0803603499496566 1.023532068317553 1.0107431732980636 1.0977628463721352 0.9477178374100462 1.0380910346180199 1.0650613058368255 0.9823117703530794 0.9862203219263818 1.0 18.423957496519968 -1.5228787455928976 0.19912482126506129 0.9927935445380883 1.311113929621934 0.193123723831219 0.040403318114246425 100.39472778821415 1.2096193817486136 0.07584303454676222 9.95692079168546 0.029999999978409117 1.5228787455928976 0.31832038508384575 SVESTS(ph)PEPSK ddPTM_PC-9_Lapatinib_30min_R1 1 SVESTSPEPSK 11 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;P18583-8 P18583-10 SON Protein SON 1 SVEST(0.023)S(0.977)PEPSK 160.56 0.0012158 70617000.0 47603.0 42041.0 47411.0 41232.0 45298.0 40854.0 40339.0 39622.0 44004.0 34734.0 True False 46924.172490678946 41943.65664749137 43513.05059175246 44264.33882591985 42633.660699294545 39106.769655325465 42427.55603975713 41462.98276722241 39047.80613733735 40737.72561985423 1.1518603892753807 1.0296023160175984 1.0681266548308632 1.0865687308853311 1.0465400326255891 0.9599644815778844 1.041480725646582 1.0178030839064496 0.9585170881092765 1.0 15.314077816688028 -1.5228787452803403 0.2507262056904087 0.9831528292517708 1.8621461592963295 0.5693519870627759 0.036305501202952506 40.14460755642509 0.5464915004594861 0.04768900411800573 14.89545457897383 0.02999999999999981 1.5228787452803403 0.8789933300445587 SVFEEEVR ddPTM_PC-9_Lapatinib_30min_R1 1 SVFEEEVR 8 0 Q03252 Q03252 LMNB2 Lamin-B2 0 98.62899999999999 0.025099 2050900.0 14474.0 13876.0 14374.0 10629.0 12050.0 14064.0 11695.0 13284.0 16049.0 12729.0 False True 14267.598105793484 13843.870974538895 13192.225205244564 11410.692117304574 11341.24269121151 13462.515504785271 12300.509875925516 13901.22313562623 14241.392616537736 14929.190689673636 0.9556846316968964 0.9273021734603842 0.883653071319498 0.7643208767637505 0.7596689550664074 0.9017578906066992 0.8239234216784201 0.9311437856602339 0.9539293128855509 1.0 13.865848338749885 -8.095560242625705 2.007593770647892 0.9877280778174902 0.8570293946785228 0.3738142849297389 0.06175917265098281 0.40035989090518065 2.8791631971977 0.060471452229889505 0.019031000304755925 8.024902367040525e-09 8.095560242625705 -0.13069868313896738 SVFGT(ph)PTLETANK ddPTM_PC-9_AZD4547_30min_R2 1 SVFGTPTLETANK 13 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 S(0.107)VFGT(0.893)PTLETANK 215.09 5.3268e-14 12323000.0 40070.0 47411.0 48499.0 51519.0 53590.0 56249.0 40697.0 62221.0 40715.0 51385.0 True False 52811.426492223705 62735.678577363105 47855.87157131633 39642.090510615424 46149.953530734194 52731.741137990626 44318.95415946437 52606.174146339814 42867.111778680104 49586.02679037675 1.0650465445735795 1.2651886557190004 0.9651080086256035 0.7994609182583032 0.9307048077441566 1.0634395322882446 0.8937790952040026 1.0609072263186288 0.8644998309684978 1.0 15.597646009831974 -5.342773822123821 7.272280515086236 0.944970285471431 1.1642238609555653 0.483562115682008 0.09013793971348082 0.1962440770892534 15.217315472158338 0.02312877673628715 0.0485817354493635 4.541780882035807e-06 5.342773822123821 0.21925357548413427 SVFGT(ph)PTLETANK ddPTM_PC-9_Lapatinib_30min_R1 2 SVFGTPTLETANK 13 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 S(0.004)VFGT(0.983)PT(0.012)LETANK;SVFGT(0.64)PT(0.353)LET(0.007)ANK 190.24 4.4e-05 28390000.0 108986.0 153411.0 156168.0 133175.0 141181.0 133736.0 136492.0 101735.0 129420.0 92748.0 True False 107431.8396544153 153055.78625504358 143328.4698659129 142969.13375877668 132877.01115252546 128016.42303384263 143558.88789951467 106461.9795018772 114843.35674698206 108779.36822105838 0.9876122780571341 1.4070295567814652 1.3176071180579465 1.3143037700700635 1.2215276970766784 1.1768447006760625 1.3197253325444795 0.9786964315285244 1.0557457597437099 1.0 16.731045426358442 -7.765582387019355 24.99927780258395 1.012915760018333 1.2565870916326147 0.5032781610394369 0.1080655954999308 84.92332590560007 512420.2977673754 0.05505867399072151 0.02795578997627111 1.7156062233912756e-08 7.765582387019355 0.24367133161428178 SVFGTPT(ph)LETANK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVFGTPTLETANK 13 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 SVFGT(0.395)PT(0.604)LET(0.001)ANK 126.32 0.00031973 13788000.0 95566.0 106740.0 109750.0 103170.0 120910.0 98815.0 113470.0 89802.0 86674.0 73758.0 True False 111743.43628546264 117336.44177991513 112366.8562291928 97389.71938165302 97218.55345969723 93632.96744613441 102721.3001483413 87444.79265308389 87941.44327890199 87129.74153199335 1.2824947523163641 1.3466864438801316 1.2896498285597757 1.1177551737128968 1.1157906789382515 1.0746384162261418 1.1789464578019304 1.0036158849498578 1.009316012335588 1.0 16.41087764299605 -5.702039686236743 0.4522666332475923 1.0091529277419289 1.4335026837744302 0.8020212720239407 0.05404465165742465 1.037386872352325 0.29842745268686044 0.04692303624995792 0.21831694439182736 1.985913434434777e-06 5.702039686236743 0.42434975603250136 SVGDES(ph)WEQTQEGDVGALYHEQLALK ddPTM_PC-9_AZD4547_30min_R2 1 SVGDESWEQTQEGDVGALYHEQLALK 26 0 O75691 O75691 UTP20 Small subunit processome component 20 homolog 1 S(0.015)VGDES(0.606)WEQT(0.378)QEGDVGALYHEQLALK 83.601 2.5311e-06 2137600.0 7437.2 10542.0 13095.0 18127.0 12578.0 12533.0 10800.0 14483.0 7068.0 13224.0 True False 9802.074896630054 13949.49533995406 12921.351743878999 13948.10020935822 10831.761812083869 11749.309528746046 11761.179077627723 12244.98513623117 7441.600050392011 12761.031785072339 0.7681255764989452 1.0931322462711806 1.0125632442193429 1.093022918857901 0.8488155185660379 0.9207178327453278 0.9216479729629521 0.9595607426160608 0.5831503420512659 1.0 13.63945736155408 -7.220348475869102 0.9780061242378825 0.833871032888519 0.9861815016778558 0.11862868742049482 0.13862965995462 1.081254082679876 2.0299322365907524 0.098523642621194 0.058291354796624215 6.02076288993132e-08 7.220348475869102 0.15231046878933674 SVGDGETVEFDVVEGEK ddPTM_PC-9_AZD4547_30min_R2 1 SVGDGETVEFDVVEGEK 17 0 H0Y449;P67809;Q9Y2T7;P16989-2;P16989;P16989-3;A0A0D9SEI8 H0Y449;P16989-2 YBX1;YBX2;YBX3 Nuclease-sensitive element-binding protein 1;Y-box-binding protein 2;Y-box-binding protein 3 0 214.65 1.3165999999999998e-21 2260600.0 6788.2 7293.5 6339.3 8874.3 9545.8 7770.2 10206.0 7780.9 4857.6 6875.3 False True 8946.706396668656 9650.9812428339 6255.23673997496 6828.467241568251 8220.530442502004 7284.328165663645 11114.314228358202 6578.54069229449 5114.362819013055 6634.597839678453 1.34849264610472 1.4546444978346473 0.9428207844890447 1.0292209726308286 1.239039749077001 1.0979306269476437 1.675205415147945 0.9915507844275487 0.770862521376416 1.0 12.695793303040432 -1.5228787533116734 0.09184008511492005 0.8294684467354185 2.1721687370888745 0.14331355533860624 0.23909593945580115 360.58292696723646 2.3842009060852742 4.446585739842346 60.96240413203647 0.02999999944521498 1.5228787533116734 1.342700290353456 SVGDGETVEFDVVEGEK ddPTM_PC-9_Lapatinib_30min_R1 2 SVGDGETVEFDVVEGEK 17 0 H0Y449;P67809;Q9Y2T7;P16989-2;P16989;P16989-3;A0A0D9SEI8 H0Y449;P16989-2 YBX1;YBX2;YBX3 Nuclease-sensitive element-binding protein 1;Y-box-binding protein 2;Y-box-binding protein 3 0 ; 199.31 8.9824e-12 13926000.0 74299.0 64090.0 83311.0 73566.0 74707.0 65441.0 71942.0 66827.0 65511.0 70665.0 False True 73239.4826352323 63941.60354267787 76461.49116975999 78976.28904898198 70312.88113961309 62642.24098042184 75666.80474509056 69932.02638395784 58132.4613185871 82879.35109480612 0.883687935146274 0.7715022221823955 0.9225638251232843 0.9529067011955801 0.8483763471939088 0.7558244623412297 0.9129753520697201 0.8437810559588267 0.7014106716652387 1.0 16.33872508701443 -6.509317757596948 24.59695768198303 0.8334962168227168 0.8804581962526424 0.04028574438200827 0.08748098005085553 1693.7583474844855 3072151.0531181805 0.027423847437378007 0.029781020067302252 3.095153858185629e-07 6.509317757596948 0.04696197942992564 SVGGDSDT(ph)EDMR ddPTM_PC-9_Lapatinib_30min_R1 1 SVGGDSDTEDMR 12 0 Q9UK61-3;Q9UK61;Q9UK61-2;Q9UK61-4;A0A087X0F1 Q9UK61-3 FAM208A Protein FAM208A 1 SVGGDS(0.105)DT(0.895)EDMR 104.59 0.0026468000000000004 0.0 13363.0 13614.0 16633.0 17281.0 15279.0 12275.0 13129.0 14685.0 16364.0 13878.0 True False 13172.441169525924 13582.477619441675 15265.498945236739 18551.902387726073 14380.319259669766 11750.026864422578 13808.755379309629 15367.318710228177 14520.913999440696 16276.793808727387 0.8092773874461103 0.8344688627903453 0.9378689147645032 1.139776211810142 0.8834859880057732 0.7218882909312508 0.8483707259291795 0.9441244320480633 0.8921237296533662 1.0 13.99052892609534 -9.063720088519396 1.3470377618156937 0.9998396646344244 0.89054436545858 0.09214342524806463 0.10355032111627635 8.348714356533998 17.889010598019738 0.10988983573275639 0.0323619054730852 8.635349339845801e-10 9.063720088519396 -0.10929529917584446 SVGGS(ph)GGGSFGDNLVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVGGSGGGSFGDNLVTR 17 0 P02545;P02545-3;P02545-5;P02545-4;A0A0C4DGC5 P02545 LMNA Prelamin-A/C;Lamin-A/C 1 S(0.013)VGGS(0.986)GGGS(0.002)FGDNLVTR 192.72 1.4809e-09 13790000.0 23459.0 24590.0 25138.0 22017.0 30778.0 26909.0 26232.0 17340.0 22378.0 20272.0 True False 27430.145363629974 27031.132690351504 25737.385256395894 20783.458870077087 24747.271841721664 25497.844669412825 23747.115056766434 16884.843373248674 22705.235914983314 23947.153126936293 1.14544493945612 1.1287827219823587 1.0747576181590415 0.8678885026504211 1.033411851109992 1.0647547344879287 0.9916466868061719 0.7050877105828595 0.9481392545756914 1.0 14.547566535979607 -4.648186623309878 0.42905852088126195 0.9054595328674745 1.385127215444928 0.36632075184914736 0.09931781013133144 6.5796621217828735 0.8702993568437472 0.08016576027708038 1.658854337680605 2.248088358592177e-05 4.648186623309878 0.4796676825774534 SVGGSGGGS(ph)FGDNLVTR ddPTM_PC-9_AZD4547_30min_R2 2 SVGGSGGGSFGDNLVTR 17 0 P02545;P02545-3;P02545-5;P02545-4;A0A0C4DGC5 P02545 LMNA Prelamin-A/C;Lamin-A/C 1 S(0.018)VGGSGGGS(0.981)FGDNLVTR;SVGGSGGGS(0.999)FGDNLVTR 167.93 2.0096e-05 67329000.0 43317.0 34124.0 58008.0 75668.0 65882.0 56979.0 40271.0 60986.0 46987.0 52208.0 True False 57090.90495042812 45153.91566880979 57238.776018246084 58223.911658946236 56735.421506098755 53416.09412259002 43855.040984735715 51562.01501886307 49470.63689413828 50380.21381087846 1.1332009261560665 0.8962628828514386 1.1361360281858646 1.1556900468408515 1.1261449131414372 1.06025937728466 0.8704814383948927 1.0234576457420559 0.9819457511602745 1.0 15.62056962435363 -7.023592912904102 23.18079702482329 0.9701323096585294 1.085839893584176 0.3491619892296669 0.07811611486404263 375.49367691591584 368933.08333674533 0.030579647169137233 0.02387227699805699 9.471245351296707e-08 7.023592912904102 0.11570758392564662 SVGGSGGGS(ph)FGDNLVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVGGSGGGSFGDNLVTR 17 0 P02545;P02545-3;P02545-5;P02545-4;A0A0C4DGC5 P02545 LMNA Prelamin-A/C;Lamin-A/C 1 S(0.055)VGGS(0.069)GGGS(0.871)FGDNLVT(0.006)R 72.66199999999999 0.011714 6402400.0 6143.9 4323.2 6515.3 7407.8 7913.3 6680.2 5451.9 7569.6 7385.8 6116.9 True False 7183.940922443679 4752.378724966553 6670.649461412842 6992.7649824116415 6362.745671099363 6329.878552179998 4935.456563662122 7370.906020654164 7493.803352439172 7225.845548646244 0.9942007304307222 0.6576917113675239 0.9231652429469078 0.96774348902624 0.8805537882402451 0.8760052383580071 0.6830282394545196 1.0200752245576432 1.0370832454124528 1.0 12.818950702374106 -7.9221219368877565 24.999901861888816 1.0218988927820676 0.8555499222752259 0.3464556510824519 0.10346430198256665 35.64850157367834 11441.708158333542 0.05591508863905419 0.026860733537702262 1.1964045695626298e-08 7.9221219368877565 -0.16634897050684172 SVGGSGGGS(ph)FGDNLVTR ddPTM_PC-9_Lapatinib_30min_R1 2 SVGGSGGGSFGDNLVTR 17 0 P02545;P02545-3;P02545-5;P02545-4;A0A0C4DGC5 P02545 LMNA Prelamin-A/C;Lamin-A/C 1 S(0.012)VGGS(0.099)GGGS(0.888)FGDNLVTR;S(0.01)VGGS(0.014)GGGS(0.975)FGDNLVTR 150.23 3.9937e-05 73038000.0 75382.0 70239.0 90013.0 68601.0 89536.0 80765.0 72831.0 78140.0 96977.0 57711.0 True False 74307.03885663423 70076.36591097144 82612.47860022822 73646.14638622753 84269.6685145488 77310.86922241065 76601.83281518005 81770.66966409475 86054.42904691765 67686.26945492609 1.0978155459744618 1.0353113929204942 1.220520487618864 1.0880514907867727 1.2450038862116044 1.142194271378685 1.1317189354953452 1.2080835644007208 1.27137201887339 1.0 16.046575584127652 -5.254510372735486 24.922407006467633 1.1691387899857848 1.0665634653002296 0.19807126438394917 0.07721828982006147 752.4114134773179 2706270.1130766394 0.01856663947245065 0.04695445735229458 5.565313418459014e-06 5.254510372735486 -0.10257532468555519 SVGKVEPSSQSPGRS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 SVGKVEPSSQSPGRSPR 17 2 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 S(0.435)VGKVEPS(0.026)S(0.043)QS(0.016)PGRS(0.48)PR 47.638999999999996 0.031837 3806400.0 9553.3 5282.2 15183.0 42447.0 31109.0 15026.0 9673.9 16089.0 11520.0 21161.0 True False 12591.050679015734 6989.567850949095 14981.663499604041 32661.499949612655 26790.052330427498 14086.421844645183 10534.858359172486 13602.814738439776 12128.92368145387 20420.159830907116 0.6165990268087146 0.3422876171796644 0.733670236847432 1.5994732764127315 1.3119413634500143 0.6898291669257434 0.5159047943996675 0.666146340238293 0.593968107100515 1.0 14.317706537947076 -10.861683504615078 4.30656173057584 1.0002896388876894 0.7961386053971911 0.03010328939410689 0.36071042965924366 0.0011373643845457343 0.00017462134704732753 0.3960007180260636 0.09590882336046795 1.375043683440096e-11 10.861683504615078 -0.20415103349049835 SVGKVEPSSQSPGRS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 SVGKVEPSSQSPGRSPR 17 2 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 S(0.008)VGKVEPS(0.007)S(0.007)QS(0.034)PGRS(0.944)PR 57.17100000000001 0.014846000000000002 3288500.0 58456.0 10839.0 23419.0 16178.0 13515.0 10704.0 7872.3 7859.0 19015.0 9450.9 True False 57622.40672048247 10813.902961446169 21493.580219954256 17367.784088225937 12720.074271512332 10246.214872242712 8279.88917454027 8224.157830690045 16873.330463173104 11084.475472467326 5.198478436224653 0.9755899580730517 1.9390705742767942 1.5668566484147752 1.1475576181396823 0.924375257782223 0.7469806934127508 0.7419528196095512 1.5222488881034277 1.0 13.436252881719074 -4.759670277310893 24.99999794652228 1.1800213863475688 5.198483452262382 0.9144972935378013 0.3691822752197983 13.170793872738104 186069.1142814661 0.1007316494590656 0.6293735991900995 1.7391206933882278e-05 4.759670277310893 4.018462065914813 SVGMIAGGT(ph)GITPMLQVIRAIMK ddPTM_PC-9_Lapatinib_30min_R1 1 SVGMIAGGTGITPMLQVIRAIMK 23 1 P00387-2;P00387;P00387-3 P00387-2 CYB5R3 NADH-cytochrome b5 reductase 3;NADH-cytochrome b5 reductase 3 membrane-bound form;NADH-cytochrome b5 reductase 3 soluble form 1 S(0.021)VGMIAGGT(0.83)GIT(0.149)PMLQVIRAIMK 52.045 0.015862 10729000.0 29575.0 34597.0 36952.0 40865.0 38756.0 31738.0 36965.0 35069.0 29868.0 30619.0 True False 29153.255076609228 34516.892772133346 33913.949198844944 43870.34842164374 36476.44827722764 30380.639724891556 38878.866828865896 36698.433765678725 26503.95131601652 35911.45335274706 0.8118093910108802 0.9611666905564812 0.9443769614590294 1.2216255351939929 1.0157330008042504 0.8459874744269457 1.0826313946965846 1.0219144684900774 0.7380361651107915 1.0 15.132156420253835 -10.3339525147704 14.811421202948706 0.9999999993514995 0.9712726604745477 0.0019453768993453746 0.1326530543648541 0.0 0.0 0.12936353138687123 0.0313752649418221 4.634975952282748e-11 10.3339525147704 -0.02872733887695178 SVGRDEREDITHTYK ddPTM_PC-9_AZD4547_30min_R2 1 SVGRDEREDITHTYK 15 2 P21980;P21980-2 P21980 TGM2 Protein-glutamine gamma-glutamyltransferase 2 0 39.005 0.042691 8972400.0 29401.0 19841.0 44077.0 65110.0 48961.0 36529.0 31383.0 36755.0 28254.0 50623.0 False True 38749.90642120959 26254.215238097957 43492.51018059981 50099.89543947229 42163.610278378015 34244.835855386926 34176.026203073205 31075.3592958763 29747.44875831579 48850.70417844199 0.7932312762506722 0.5374378052401555 0.8903149076772824 1.0255716121607428 0.8631116170682547 0.7010100761351831 0.699601505809106 0.6361291985139894 0.6089461607278828 1.0 15.576091738210335 -6.773772251489321 24.025077057967213 0.7045494188794051 0.8212403284286962 0.07423095505135247 0.1519057376777407 335.4822495003545 653530.9482450126 0.055889316411934606 0.04967537082290192 1.683556704136122e-07 6.773772251489321 0.11669090954929107 SVGRDEREDITHTYKYPEGSSEER ddPTM_PC-9_AZD4547_30min_R2 1 SVGRDEREDITHTYKYPEGSSEER 24 3 P21980;P21980-2 P21980 TGM2 Protein-glutamine gamma-glutamyltransferase 2 0 37.373000000000005 0.030070999999999997 9191400.0 14060.0 5280.2 21796.0 52188.0 34207.0 13577.0 14868.0 15009.0 12736.0 26910.0 False True 18530.78753383243 6986.921390061229 21506.970798746603 40156.86289656243 29457.94850580006 12728.028043707413 16191.223196867502 12689.70392250871 13409.198958940684 25967.88909076654 0.7136039232554126 0.2690600443355091 0.8282140578917476 1.5464045905387471 1.1343990419411676 0.49014488621769203 0.6235094096510391 0.4886690588578036 0.5163761641183465 1.0 14.664441122789546 -6.778379722480004 24.982476755046683 0.5917672923249767 0.8954847002534065 0.14230749461554193 0.3324293155906691 512.8032688180807 756242.7857941779 0.13085526760072225 0.11569493513872513 1.6657901031845083e-07 6.778379722480004 0.30371740792842983 SVHELEK ddPTM_PC-9_AZD4547_30min_R2 2 SVHELEK 7 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 108.46 0.0081886 7029900.0 24735.0 22523.0 84431.0 161101.0 128773.0 104511.0 53994.0 101975.0 78041.0 99294.0 False True 32600.215480038765 29803.11928872942 83311.38977376453 123961.65343563842 110895.0917337796 97975.91064859 58799.36139976215 86217.10690238042 82166.08793614079 95817.74728274163 0.3402314957775114 0.31103965741112194 0.8694776503973424 1.293723312758011 1.1573544033189105 1.0225236287332031 0.6136583573213779 0.8998031089999289 0.8575247307128067 1.0 16.548005275025375 -5.304363050077529 4.541393690236578 0.9742100536059273 0.3188680542820819 0.6933266016165195 0.17076975398919603 0.11678789948015739 5.560026475803817 0.05095524858382189 0.11788118339463825 4.961773667291831e-06 5.304363050077529 -0.6553419993238454 SVHELEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVHELEK 7 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 105.14 0.0023732 0.0 26200.0 28440.0 83380.0 72571.0 94098.0 93428.0 67645.0 62886.0 82311.0 54176.0 False True 30635.142526412288 31263.335246587903 85368.09542041096 68505.08214835635 75660.17238814497 88528.47120940589 61237.175892610714 61235.30913322468 83514.64265788671 63997.679943019975 0.4786914549666197 0.4885073220532848 1.333924846907232 1.0704307126344192 1.1822330505654055 1.3833075087757367 0.9568655605505221 0.9568363913777068 1.3049635976217195 1.0 15.96573198473444 -5.25104063914372 24.866791187723987 1.1469770784348194 0.4835992537135624 0.7654301799235246 0.14724467973223007 296.0111465901728 707855.7496467899 0.03766806060523493 0.09730315417254351 5.609954783758452e-06 5.25104063914372 -0.6633778247212571 SVHELEK ddPTM_PC-9_Lapatinib_30min_R1 2 SVHELEK 7 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 109.01 0.0081203 7787600.0 65465.0 56504.0 117942.0 64391.0 106858.0 115495.0 85740.0 89428.0 160516.0 58566.0 False True 64531.45709518929 56373.16845959542 108245.26402928564 69126.52894207902 100572.82253091113 110555.54808199486 90179.19767095795 93583.15135296475 142436.99777158542 68689.05506571036 0.9394721915078935 0.8207008875819717 1.5758735351030004 1.0063689022355913 1.4641753687643488 1.6095074823235456 1.3128612350932671 1.3624172186302435 2.0736491080758817 1.0 16.067792617452163 -4.99288728304453 0.6924734636223209 1.489927366152496 0.560268521953943 0.2941167289593287 0.3069379448950717 2.9342649191719707 1.2919621113777824 0.13414077139872593 2.0489910023150135 1.016512484674866e-05 4.99288728304453 -0.929658844198553 SVHIS(ph)TPEKEPCAPLTIPSIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVHISTPEKEPCAPLTIPSIR 21 1 E9PHV5;P28290-3;P28290;P28290-2 E9PHV5 SSFA2 Sperm-specific antigen 2 1 S(0.016)VHIS(0.492)T(0.492)PEKEPCAPLTIPSIR 56.553000000000004 0.0065854 1703000.0 12314.0 14254.0 19212.0 17311.0 17441.0 20089.0 14895.0 17788.0 19234.0 12652.0 True False 14398.516987413774 15669.042918595778 19670.08694191573 16341.120793019241 14023.561251266077 19035.497475336673 13484.03776953858 17321.08384794391 19515.26086284697 14945.707446823113 0.9633881192070536 1.0483975398519136 1.3161027680959219 1.0933654931465113 0.9383002645516757 1.2736431208134542 0.9022013723682764 1.1589336877877743 1.305743534207554 1.0 13.867443567356192 -7.977299977987148 24.99988157967846 1.1793609712611914 1.0834693026427376 0.05102573048104786 0.14425910248925702 594.5704332420869 654808.8767488285 0.07704858474096642 0.03700968726405338 1.0536588566359585e-08 7.977299977987148 -0.09589166861845388 SVIAGEAVAS(ph)VR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVIAGEAVASVR 12 0 Q08EI0 Q08EI0 AOF1 1 SVIAGEAVAS(1)VR 84.352 0.010256 3726300.0 35213.0 39207.0 40513.0 41060.0 53431.0 35950.0 36575.0 32825.0 28300.0 31305.0 True False 41173.865411547915 43099.21184996384 41478.983566408075 38759.54131831608 42961.57910764282 34064.718713641945 33110.35121993109 31963.378530962374 28713.83396166004 36980.348689756356 1.113398517601138 1.1654625599001565 1.121649336364907 1.0481118402502398 1.161740779354611 0.9211573151844821 0.8953498923903532 0.8643341575580196 0.7764619582836394 1.0 15.174471207607152 -6.848589205767257 4.709352202569838 0.8776024351750729 1.120257227828823 0.7903379279781003 0.05945414521553976 0.09227214315771827 3.604553864876173 0.02112064712981992 0.01873517782259515 1.4171335968208514e-07 6.848589205767257 0.24265479265375012 SVICDIS(ph)PLR ddPTM_PC-9_AZD4547_30min_R2 1 SVICDISPLR 10 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 SVICDIS(1)PLR 102.05 0.0033668 7752300.0 35430.0 32727.0 42578.0 67993.0 60158.0 58859.0 45917.0 60478.0 48973.0 55708.0 True False 46696.00301021929 43305.36273863371 42013.387900028996 52318.26433137823 51806.100102666715 55178.537425394 50003.524046984436 51132.51474618439 51561.61279963897 53757.67987619555 0.8686387343680128 0.8055660668088053 0.7815327595384739 0.9732240017029695 0.9636967261603674 1.0264307825871708 0.9301652184793509 0.9511666958831382 0.9591487749915149 1.0 15.714183253839163 -5.768975895205223 24.99991739882945 0.9701231891845239 0.8172778696379903 0.8282139638307852 0.03200521226632821 63.44168355326076 210447.4831116767 0.009130263913967835 0.013844920686593754 1.7022529865011887e-06 5.768975895205223 -0.15284531954653358 SVICDIS(ph)PLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SVICDISPLR 10 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 SVICDIS(1)PLR;SVICDIS(1)PLR;SVICDIS(1)PLR 70.488 0.035644 11426500.0 68390.0 85185.0 98176.0 98993.0 109776.0 91200.0 112684.0 98379.0 87841.0 73197.0 True False 79967.07623592876 93641.60383194746 100516.88817455349 93446.7431496364 88266.18083360959 86417.31145157569 102009.75575848819 95796.65549116691 89125.50844615477 86467.0366728667 0.9248273019748621 1.0829745928060945 1.1624879496546414 1.0807210093619402 1.02080728367678 0.9994249228005913 1.1797531138302417 1.1078979825988167 1.0307454941857894 1.0 16.399862626839976 SVIEPLPVT(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 3 SVIEPLPVTPTR 12 0 H0YCM0;E9PM17;B3KNX7;Q13153;Q13153-2 H0YCM0 PAK1 Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase PAK 1 1 SVIEPLPVT(0.985)PT(0.015)R;SVIEPLPVT(0.973)PT(0.027)R;SVIEPLPVT(0.989)PT(0.011)R 113.52 0.0020141 52953200.0 64734.0 82985.0 76017.0 86581.0 78444.0 95616.0 84382.0 144034.0 112015.0 78176.0 True False 85318.06544915431 109808.27838987755 75008.96491137454 66621.08811311539 67553.40464200258 89637.11640473806 91891.83453040593 121776.85487205119 117935.8842168452 75439.0820349223 1.1309531233380972 1.4555887403169228 0.994298484128576 0.8831110654590828 0.8954696003688211 1.18820529077015 1.2180932223945582 1.6142409423232136 1.5633260776191609 1.0 16.20302450052902 -7.479793744015473 3.0678944864248914 1.439820595429296 1.0856022950038844 0.2603158326678272 0.21915386556304392 0.31619971467430047 5.955587726170034 0.11290081090483348 0.0663064751225223 3.3128842027163805e-08 7.479793744015473 -0.3542183004254116 SVIEPLPVT(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SVIEPLPVTPTR 12 0 H0YCM0;E9PM17;B3KNX7;Q13153;Q13153-2 H0YCM0 PAK1 Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase PAK 1 1 SVIEPLPVT(0.993)PT(0.007)R;S(0.002)VIEPLPVT(0.987)PT(0.011)R;SVIEPLPVT(0.973)PT(0.027)R;SVIEPLPVT(0.978)PT(0.022)R;SVIEPLPVT(0.977)PT(0.023)R 127.78 0.00054818 40713100.0 74428.0 94046.0 76148.0 69769.5 95116.0 73774.8 88251.0 72523.3 69957.8 70605.0 True False 87027.19037999303 103382.26535163884 77963.65711289813 65860.54111077078 76478.70259591904 69905.91961488704 79891.22639808993 70619.64021978808 70980.80047784532 83405.1275911274 1.0434273394631308 1.2395192998018578 0.9347585617888542 0.789646188584897 0.916954446384119 0.8381489440023782 0.9578694824344196 0.8467062189027881 0.8510364114039941 1.0 16.347848460136568 -5.400405140413522 5.4383791434953155 0.8804371775609897 1.1385947483381256 0.6546202664631239 0.07303748258550673 0.11374620453683962 4.5376719174611955 0.01779418997590159 0.037875434713773526 3.977359613790519e-06 5.400405140413522 0.25815757077713586 SVIEPLPVT(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 4 SVIEPLPVTPTR 12 0 H0YCM0;E9PM17;B3KNX7;Q13153;Q13153-2 H0YCM0 PAK1 Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase PAK 1 1 SVIEPLPVT(0.984)PT(0.016)R;S(0.002)VIEPLPVT(0.998)PTR;SVIEPLPVT(0.972)PT(0.028)R;S(0.001)VIEPLPVT(0.99)PT(0.009)R 164.92 0.00016508 48664300.0 77802.0 106092.0 109945.0 90583.0 152854.0 138385.0 182506.0 154333.0 158801.0 155438.0 True False 76692.52921286068 105846.35049227308 100905.74649997326 97244.7759960299 143863.4282425265 132466.596141191 191955.2676712837 161503.87460031625 140915.15913133582 182305.25119188373 0.42068195354470983 0.5805995702277685 0.5534988478953129 0.5334173061952878 0.7891348565220668 0.7266197505290974 1.0529332886261349 0.8858980942371585 0.7729626997031307 1.0 17.475996592365583 -6.4893842084659585 1.2465713800118834 0.9131241879089 0.5087288506835237 0.7830107186814615 0.09253498409872367 0.20739950725705453 0.6705520850994738 0.04028913819368486 0.04683327850803835 3.240528098328831e-07 6.4893842084659585 -0.40439533722537635 SVIEPLPVT(ph)PTRDVATSPISPTENNTTPPDALTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVIEPLPVTPTRDVATSPISPTENNTTPPDALTR 34 1 H0YCM0;E9PM17;B3KNX7;Q13153;Q13153-2 H0YCM0 PAK1 Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase PAK 1 1 SVIEPLPVT(0.396)PT(0.132)RDVAT(0.197)S(0.197)PIS(0.06)PT(0.01)ENNT(0.004)T(0.005)PPDALTR;S(0.001)VIEPLPVT(0.503)PT(0.16)RDVAT(0.16)S(0.068)PIS(0.02)PT(0.022)ENNT(0.03)T(0.034)PPDALT(0.001)R 60.637 0.0017503 0.0 12906.400000000001 9099.3 7943.799999999999 13196.6 15425.4 20510.8 20381.7 24429.0 18382.1 18479.699999999997 True False 15091.19860698043 10002.618368821288 8133.21031902926 12457.237285954465 12402.903602160417 19435.177540800203 18450.997825270508 23787.764634665025 18650.903436983415 21829.923324775296 0.691307907153896 0.45820675684504486 0.3725716393056996 0.5706496124893142 0.5681606580855036 0.8902998536299375 0.8452158787168086 1.0896861285659087 0.854373291170293 1.0 14.414019442578075 -6.779579278802486 1.9187783849554294 0.9589443444392236 0.5042330825461451 0.7991863446502292 0.10132501246613353 0.14032779277159815 1.0652745367856975 0.04105909638888444 0.03715480205211939 1.6611954051968103e-07 6.779579278802486 -0.45471126189307853 SVKTS(ph)PTTQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVKTSPTTQSK 11 1 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 S(0.001)VKT(0.098)S(0.856)PT(0.02)T(0.02)QS(0.005)K 55.841 0.039218 17883000.0 85573.0 55265.0 67305.0 124100.0 124300.0 152180.0 120260.0 139820.0 128040.0 112110.0 True False 100058.81875620932 60751.34396633894 68909.80645563379 117147.07933762869 99944.30729501601 144199.41290242074 108868.10219299838 136149.8731515355 129912.34277211849 132434.65553772825 0.7555334995204813 0.45872693759551464 0.5203306202280462 0.8845651378936504 0.7546688356549066 1.0888344317197316 0.8220514619149957 1.0280532131013762 0.9809542845460779 1.0 17.01492117082806 -6.041728707994618 1.5660630316697126 0.9644932510520416 0.5657985267350751 0.6472333085431257 0.11966162727123225 0.22751937014170642 1.1230537471673034 0.039940474567856314 0.06589008219698461 9.0838779824642e-07 6.041728707994618 -0.3986947243169665 SVLEDFFTATEGQY(ph)QPQP ddPTM_PC-9_AZD4547_30min_R2 1 SVLEDFFTATEGQYQPQP 18 0 Q573B4;P06239;P06239-3 Q573B4 LCK Non-specific protein-tyrosine kinase;Tyrosine-protein kinase Lck 1 SVLEDFFTATEGQY(1)QPQP 160.52 5.4828e-18 0.0 1139.9 954.06 748.52 1021.2 3047.9 1202.0 1221.7 2630.1 1017.9 887.24 True False 1502.3644886070836 1262.4412373398375 738.5941357257205 785.7781173827223 2624.7516955835936 1126.8387499842615 1330.428933253499 2223.678478685465 1071.7041159159635 856.1779976548381 1.7547338202128744 1.4745079186778884 0.8626642330786447 0.9177742473353104 3.065661232562698 1.3161267319071406 1.5539162848119017 2.5972151641088126 1.2517305032965973 1.0 9.74176695093194 SVLPPDGNGS(ph)PVLPDKR ddPTM_PC-9_Lapatinib_30min_R1 2 SVLPPDGNGSPVLPDKR 17 1 Q8N6S5 Q8N6S5 ARL6IP6 ADP-ribosylation factor-like protein 6-interacting protein 6 1 SVLPPDGNGS(1)PVLPDKR;SVLPPDGNGS(1)PVLPDKR 117.22 5.9191e-05 19733500.0 182654.0 185972.0 80830.0 63468.0 79661.0 88517.0 96813.0 70671.0 137372.0 35791.0 True False 180049.32046535844 185541.39326008523 74184.46941282308 68135.6484430413 74975.49659955183 84731.3342532052 101825.50343035284 73954.63265716966 121899.71876870979 41977.42666149026 4.289193854527872 4.420027810573233 1.7672467159803127 1.623149722647205 1.7860908245796239 2.0184975829148915 2.4257204771384115 1.7617714695459172 2.9039350065862797 1.0 15.35732610748254 -5.25980550227644 24.921600547161244 1.9455165857998429 4.354611095392784 0.8091232725516444 0.4745448319035007 51.03703518193134 778451.8988290426 0.11784485274000306 0.279939403721073 5.497870395147221e-06 5.25980550227644 2.409094509592941 SVNEILGLAES(ph)SPNEPK ddPTM_PC-9_Lapatinib_30min_R1 2 SVNEILGLAESSPNEPK 17 0 Q9H8G2;Q9H8G2-2 Q9H8G2 CAAP1 Caspase activity and apoptosis inhibitor 1 1 SVNEILGLAES(0.5)S(0.5)PNEPK;SVNEILGLAES(0.597)S(0.403)PNEPK 103.5 0.0064266 0.0 20455.9 13911.3 16589.0 12511.599999999999 15702.7 15636.6 13848.7 16980.6 15106.3 11752.9 True False 20164.195114847374 13879.089239557723 15225.116455391819 13431.744801474068 14779.09805869602 14967.859068694917 14565.71792379049 17769.580666727998 13404.869417608821 13784.37310524514 1.462830043912162 1.0068712689064214 1.1045200488369293 0.9744182560150746 1.0721632348352768 1.085857075574909 1.0566833770806767 1.2891105406865715 0.9724685566228679 1.0 13.750746036558812 -4.755710709799881 24.9976943844777 1.0709071669507197 1.4628306733010288 0.6501151308436702 0.0879196585380595 115.80884804174359 505293.31433706894 0.02125125582492157 0.1839373098647348 1.755049177675736e-05 4.755710709799881 0.39192350635030904 SVNEILGLAESS(ph)PNEPK ddPTM_PC-9_AZD4547_30min_R2 1 SVNEILGLAESSPNEPK 17 0 Q9H8G2;Q9H8G2-2 Q9H8G2 CAAP1 Caspase activity and apoptosis inhibitor 1 1 SVNEILGLAES(0.196)S(0.804)PNEPK 160.64 1.8837000000000002e-17 0.0 11344.0 12709.0 14581.0 20490.0 16357.0 14849.0 14408.0 10898.0 13443.0 14875.0 True False 14951.156030141896 16816.93571195941 14387.64641294384 15766.347067344295 14086.112892372066 13920.489682625861 15690.284088005583 9213.964511126653 14153.569535571578 14354.230777597617 1.0415853180705363 1.1715664860429367 1.0023279293654923 1.0983763122960613 0.9813213338018784 0.9697830485177452 1.093077318534764 0.6418988696703077 0.9860207596537177 1.0 13.809188400231795 -6.928092503754474 0.9704898554812237 0.8875370587394052 1.0831576074938425 0.24231659585913978 0.1165185119990666 0.6799019937609754 1.344657300697076 0.07201870353552711 0.055688819436054283 1.1800692567655774e-07 6.928092503754474 0.19562054875443724 SVNEILGLAESS(ph)PNEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVNEILGLAESSPNEPK 17 0 Q9H8G2;Q9H8G2-2 Q9H8G2 CAAP1 Caspase activity and apoptosis inhibitor 1 1 SVNEILGLAES(0.317)S(0.683)PNEPK 98.169 0.010355 0.0 9581.4 11034.0 11501.0 13898.0 14184.0 12606.0 13167.0 15612.0 13606.0 12498.0 True False 11203.341778723916 12129.382598834418 11775.227457785395 13119.340117923934 11404.747020695962 11944.919168405295 11919.726439175187 15202.201542281333 13804.962009976898 14763.788465886431 0.7588392237270691 0.8215630173014782 0.7975749236040276 0.8886160993323495 0.7724810638575625 0.8090687018447545 0.8073623153513203 1.0296951610630232 0.9350555273719194 1.0 13.8497753516006 -7.7533566136381875 24.9999424237034 0.9867815136608612 0.8098392005591242 0.8179653840081929 0.03897295965292005 66.67042461164534 206212.88582800434 0.018002596087927984 0.010160624881110157 1.7645882635369327e-08 7.7533566136381875 -0.17694231310173703 SVNFS(ph)LTPNEIK ddPTM_PC-9_Lapatinib_30min_R1 1 SVNFSLTPNEIK 12 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 SVNFS(0.92)LT(0.08)PNEIK 91.712 0.0062558 16497000.0 85273.0 79679.0 86357.0 75998.0 89390.0 95648.0 90736.0 81868.0 93087.0 78183.0 True False 84056.99138284686 79494.50817096308 79257.06080766015 81587.14644189592 84132.25594750185 91557.35800637817 95433.86610534231 85671.88615382767 82602.56181043356 91696.82737770096 0.9166837478096654 0.8669275747515637 0.8643380918861983 0.8897488470984599 0.9175045457239158 0.998479016392265 1.0407542859934338 0.9342949871203674 0.900822462157737 1.0 16.484584198368267 -6.5539921184480905 3.691718694218695 0.9745873071237624 0.8829997432629615 0.5569580245502731 0.0381679292236048 0.18784897421650662 5.49189882797628 0.014019678673016399 0.014537735034493654 2.792594520626271e-07 6.5539921184480905 -0.09158756386080091 SVNFSLT(ph)PNEIK ddPTM_PC-9_AZD4547_30min_R2 3 SVNFSLTPNEIK 12 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 SVNFS(0.018)LT(0.982)PNEIK;SVNFS(0.001)LT(0.999)PNEIK;SVNFS(0.026)LT(0.974)PNEIK 164.65 0.00013727 131190000.0 200282.0 180888.0 213103.0 225629.0 213618.0 193091.0 196942.0 201628.0 167771.0 187997.0 True False 263967.5098756063 239356.50854236502 210277.1149809735 173613.71998330028 183960.82801508417 181016.98924560015 214469.45647279263 170471.0255505087 176639.0325487153 181415.2822518331 1.4550456091630564 1.3193844838832285 1.1590926209241603 0.9569961131626 1.0140315949773044 0.9978045234045936 1.182201707654789 0.9396729064636791 0.9736722857973585 1.0 17.468936466688426 -5.2609716627811745 1.821906864047779 1.0133564854876724 1.4510355049549633 0.8399361016019788 0.06627134469135249 0.15970158841575266 0.9243699174005521 0.019531996353291725 0.08512066266590039 5.483127405336339e-06 5.2609716627811745 0.4376790194672908 SVNFSLT(ph)PNEIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SVNFSLTPNEIK 12 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.007)VNFS(0.021)LT(0.972)PNEIK;SVNFS(0.003)LT(0.996)PNEIK;SVNFS(0.052)LT(0.948)PNEIK;SVNFS(0.009)LT(0.991)PNEIK 160.46 4.2021e-12 30372000.0 105593.0 110113.0 88276.0 95912.0 117683.0 96209.0 123774.0 109734.0 91469.0 67369.7 True False 123467.80934318533 121044.29092853512 90380.83462859434 90538.36159089925 94623.86094448407 91163.63067373516 112049.23067384139 106853.59877278356 92806.56108265328 79583.29331174816 1.5514287510009201 1.5209761482774231 1.1356759800646783 1.1376553774450786 1.1889915207934176 1.1455121656831144 1.407949156299876 1.3426636964395358 1.166156327799934 1.0 16.280177981348352 -5.251098629166355 22.620450192267953 1.2070208810653045 1.5362027190951049 0.6160532210881848 0.10852301273764542 134.71564952994237 294684.42947867804 0.028871019193545566 0.07419158479337862 5.609205753550089e-06 5.251098629166355 0.3291818380298004 SVNFSLT(ph)PNEIK ddPTM_PC-9_Lapatinib_30min_R1 3 SVNFSLTPNEIK 12 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 S(0.348)VNFS(0.151)LT(0.501)PNEIK;SVNFS(0.057)LT(0.943)PNEIK;S(0.001)VNFSLT(0.998)PNEIK 194.77 3.791e-05 67501000.0 136699.0 124803.0 125502.0 120368.0 146162.0 133752.0 134380.0 121157.0 139246.0 101288.0 True False 134749.64719247379 124514.02632137369 115183.71001172948 129220.26425587686 137565.03852554818 128031.73875114029 141337.53887361012 126786.39652537386 123562.64915461477 118795.4958422238 1.1342992950796655 1.048137603522821 0.9695966096619416 1.0877539029551975 1.1579987738613662 1.077749100194703 1.1897550312961793 1.0672660240735308 1.04012907457975 1.0 16.858120611507523 -4.74113715243158 23.771846474584564 1.0770399361024126 1.1342996709869264 0.07726845543663119 0.06256742479386622 2549.8765552669834 2985356.873338869 0.01637539519150088 0.6108814971263448 1.8149424041108296e-05 4.74113715243158 0.05725973488451386 SVNFSLTPNEIK ddPTM_PC-9_Lapatinib_30min_R1 1 SVNFSLTPNEIK 12 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 0 118.76 0.0024938000000000004 0.0 13667.0 14907.0 12619.0 14540.0 16558.0 11589.0 14818.0 14199.0 10055.0 12736.0 False True 13472.106073779156 14872.48375738335 11581.514530748662 15609.320104018107 15584.090994280505 11093.365485278473 15585.203534969167 14858.737375997955 8922.500016155956 14937.40063034674 0.9019043143563613 0.9956540716440647 0.7753366745228565 1.0449823560537232 1.043293366760208 0.7426570231196219 1.0433678469670522 0.9947338056804226 0.5973261504434082 1.0 13.866641495281643 SVNGGPGS(ph)PDLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVNGGPGSPDLAR 13 0 A0A087X2C4;H0YAH0;O60245;O60245-2 A0A087X2C4 PCDH7 Protocadherin-7 1 S(0.079)VNGGPGS(0.921)PDLAR;S(0.001)VNGGPGS(0.999)PDLAR 81.327 0.011759 20360700.0 55250.0 54110.0 121818.0 65546.0 167366.0 95481.0 61654.0 61921.0 92785.0 57490.0 True False 64602.733762758726 59481.68319946804 124722.60311733781 61873.67012299918 134571.8337468839 90473.8082753059 55813.6867836946 60295.63936072266 94141.8050930256 67912.48190941048 0.9512645090623153 0.8758578913197663 1.8365195853643996 0.9110795009013725 1.9815478681281502 1.3322117780350058 0.8218472542079283 0.8878432604061203 1.386222421065436 1.0 16.051389137139665 -7.234658571037893 22.727750912354107 1.0146318799554535 1.3304750517687853 0.12575506192784647 0.3738829833329501 492.1577884597621 417673.34801173594 0.14375411222195503 0.11129698151085744 5.825610293494042e-08 7.234658571037893 0.3158431718133319 SVPAGLTLQS(ph)VSPQSLQGK ddPTM_PC-9_Lapatinib_30min_R1 1 SVPAGLTLQSVSPQSLQGK 19 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;Q9HAU0-3;H0YG48 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 SVPAGLT(0.001)LQS(0.682)VS(0.315)PQS(0.001)LQGK 163.44 1.1399e-07 4716400.0 42073.0 32181.0 40099.0 34366.0 36667.0 35298.0 31925.0 26595.0 37329.0 28104.0 True False 41473.031304756754 32106.486871694746 36802.21500661626 36893.39028161533 34510.31915009566 33788.386823656896 33577.920289775306 27830.700789820814 33124.61492820346 32961.73895377392 1.2582173338281457 0.9740531868394869 1.1165131505418535 1.1192792447435864 1.0469811437586316 1.0250790127014318 1.0186938358096194 0.8443335113129511 1.0049413647337586 1.0 15.008504735960365 -6.93557962350346 1.2254994802764905 0.947795633947393 1.1072476336496295 0.41704741946416335 0.07858644430649515 0.4432936772506566 1.3777433011725715 0.04143776789837209 0.03175177979973135 1.1598995407960326e-07 6.93557962350346 0.15945199970223656 SVPAGLTLQSVS(ph)PQSLQGK ddPTM_PC-9_AZD4547_30min_R2 2 SVPAGLTLQSVSPQSLQGK 19 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;Q9HAU0-3;H0YG48 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 SVPAGLTLQS(0.008)VS(0.968)PQS(0.024)LQGK;SVPAGLTLQS(0.32)VS(0.651)PQS(0.029)LQGK 167.97 6.8618e-08 10507200.0 47082.0 31371.0 44481.0 59573.0 51544.0 44928.0 40312.0 51451.0 43982.0 42404.0 True False 62053.0966335632 41511.06225665899 43891.15287663093 45839.36524367504 44388.00531420347 42118.64505764799 43899.68990530822 43500.430176360554 46306.79872896742 40919.448866773084 1.5164695114931228 1.0144579999552805 1.0726232657613062 1.1202341799108875 1.0847654732282301 1.0293062644802302 1.072831895860531 1.0630746840699326 1.1316574394668573 1.0 15.32049909348587 -4.75717855824283 24.99986795735115 1.0690527786246493 1.5164701691292781 0.9187666608769405 0.04022093845454764 31.711370435190894 186038.5762708342 0.009750928211611182 0.0738412910908915 1.749127394825999e-05 4.75717855824283 0.4474173905046288 SVPAGLTLQSVS(ph)PQSLQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVPAGLTLQSVSPQSLQGK 19 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;Q9HAU0-3;H0YG48 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 SVPAGLTLQS(0.005)VS(0.993)PQS(0.002)LQGK;SVPAGLT(0.005)LQS(0.333)VS(0.643)PQS(0.019)LQGK 249.14 5.4036e-54 10326100.0 52413.0 54239.0 51622.0 53012.0 64964.0 55362.0 58910.0 53616.0 45525.0 41760.0 True False 61285.48569606289 59623.48946693673 52852.86425752523 50041.909507222874 52234.770547976004 52458.71926076899 53329.61832853423 52208.636810847776 46190.71700016158 49330.75742802188 1.2423382265209297 1.208647354623186 1.071397785339956 1.0144159975698452 1.0588682045717897 1.0634079425460088 1.0810622238336205 1.0583384389956911 0.9363472082819343 1.0 15.590199818296044 -5.267216074944299 2.866514698880122 1.0373499433586237 1.2382461688724997 0.7905406251680074 0.039656979310432376 0.11909552319300945 1.9357910816495496 0.01091643255005243 0.03282503165978036 5.4048534785315205e-06 5.267216074944299 0.20089622551387598 SVPAGLTLQSVS(ph)PQSLQGK ddPTM_PC-9_Lapatinib_30min_R1 1 SVPAGLTLQSVSPQSLQGK 19 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;Q9HAU0-3;H0YG48 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 SVPAGLTLQS(0.33)VS(0.625)PQS(0.045)LQGK 153.68 2.2026e-05 4151900.0 22005.0 19139.0 23190.0 21768.0 20226.0 19311.0 15317.0 15075.0 22696.0 15203.0 True False 21691.20466477723 19094.684821396666 21283.407715988695 23368.89133591928 19036.34644584597 18485.11354613968 16110.039313343415 15775.439533993183 20139.737480524684 17830.81829327586 1.2165007969913053 1.0708810166383345 1.1936304529565438 1.3105899545132973 1.06760924444083 1.0366946284854779 0.9034941104984865 0.884728859580282 1.1294903660209208 1.0 14.122085292302698 -6.620260748527765 2.747246608142797 0.9749501419554669 1.1884000437984537 0.5604661843388876 0.08514603369852324 0.20363738252737637 3.1135365549650356 0.03097741414882886 0.031175388304416445 2.3973931023876253e-07 6.620260748527765 0.21344990184298673 SVPGTTSSPLVGDIS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 SVPGTTSSPLVGDISPK 17 0 Q9UQR0;H0Y6S1;B4DRC2;Q9UQR0-2 Q9UQR0 SCML2 Sex comb on midleg-like protein 2 1 SVPGTTSSPLVGDIS(1)PK;SVPGTTSSPLVGDIS(1)PK 157.54 2.8019e-05 6588500.0 35339.0 30005.0 27269.0 32948.0 29353.0 27926.0 35632.0 37748.0 32867.0 32789.0 True False 46576.06690313685 39703.52947024488 26907.39524275192 25352.347641525612 25277.842619661144 26179.78280537477 38803.17897166952 31914.913962746257 34604.28252068966 31641.06709019484 1.4720131520965731 1.2548100655729306 0.8503946837839164 0.801248187024071 0.7988934933074499 0.8273988589179898 1.226354941224284 1.0086547925760785 1.0936509322535801 1.0 14.949510634852333 -5.05002716596723 3.509335258492292 0.9468314353688069 1.4480070181174962 0.6240376212771908 0.13276085490352327 0.16178409994363901 3.9072165512319983 0.038616575274061433 0.1476368698998032 8.911951903921565e-06 5.05002716596723 0.5011755827486893 SVPGTTSSPLVGDIS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 SVPGTTSSPLVGDISPK 17 0 Q9UQR0;H0Y6S1;B4DRC2;Q9UQR0-2 Q9UQR0 SCML2 Sex comb on midleg-like protein 2 1 SVPGTTSSPLVGDIS(1)PK;SVPGTTSSPLVGDIS(1)PK 213.69 3.1959e-22 7043700.0 87326.0 80586.0 61502.0 73047.0 85067.0 78977.0 79151.0 68902.0 68136.0 65900.0 True False 86080.71522637273 80399.40806818924 56445.54296458544 78419.12005764853 80063.52630815684 75599.33781437892 83249.05149118253 72103.4384591176 60461.806176111604 77290.72719376942 1.1137262948835587 1.040220618789448 0.7303016159115093 1.0145993304093286 1.03587492594598 0.9781165290999249 1.0770897688991266 0.9328860146231103 0.7822646825994098 1.0 16.238007719520766 -7.998038243769931 24.8051338127726 0.8799466666938777 0.9921027233473201 0.13713564066792294 0.10928976727720777 101.87499945050922 1288148.1240773676 0.061454935520543284 0.029201421361699346 1.0045273281745324e-08 7.998038243769931 0.11215605665344242 SVPHLQK ddPTM_PC-9_AZD4547_30min_R2 2 SVPHLQK 7 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YN28;H0YNP5;H0YL33 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ; 100.45 0.009665100000000001 68368000.0 331860.0 359510.0 480300.0 632200.0 567420.0 487590.0 409020.0 627900.0 480720.0 497330.0 False True 437384.57688318845 475714.5768987752 473930.9081775551 486456.05739263404 488643.5273821451 457100.92022032145 445421.9876232677 530872.482706591 506129.8777906694 479918.6280754703 0.9113723687641625 0.9912400750236476 0.987523468463963 1.013621953670312 1.018179955509672 0.9524550485846934 0.9281198135806102 1.1061718625831458 1.0546160290137294 1.0 18.87243028688772 -7.762177270349401 24.999999997933813 1.0602954568519813 0.9757907141952935 0.4579456878391024 0.040427270267972944 17.655415463371227 598084.428524217 0.020947167690979145 0.010994103999582828 1.7291104267465386e-08 7.762177270349401 -0.08450474265668784 SVPHLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVPHLQK 7 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YN28;H0YNP5;H0YL33 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ; 100.19 0.009736 57710000.0 304510.0 326290.0 400340.0 417960.0 484220.0 369880.0 386790.0 404150.0 376490.0 327050.0 False True 356057.52865335153 358681.91482451407 409885.6238979046 394543.05624460295 389340.5670023538 350482.84166347375 350150.4510829013 393541.49073232035 381995.4540008964 386341.5760736242 0.921613283954452 0.9284062007247206 1.0609410151078165 1.0212285725350352 1.007762537387791 0.9071838584534921 0.9063235042975907 1.0186361373059267 0.9887505711476946 1.0 18.55951741570758 -8.95229977496219 0.0029083357009178873 1.963055648111663 0.002966264450608728 0.027554624522452498 0.05184377691345277 197096.3150884941 255.33278822683948 86620.27336856369 85454.89396719742 1.1160925907110244e-09 8.95229977496219 -1.9600893836610542 SVPHLQK ddPTM_PC-9_Lapatinib_30min_R1 2 SVPHLQK 7 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YN28;H0YNP5;H0YL33 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ; 107.59 0.0082959 136952000.0 876120.0 828470.0 907710.0 830410.0 811550.0 805800.0 899340.0 768750.0 832850.0 748770.0 False True 863626.3681392687 826551.7286160433 833081.5876619255 891481.1215665542 763816.2245686894 771337.8124115457 945903.4246955834 804468.9314598507 739045.6627006952 878193.8968266916 0.983411944970169 0.9411950272061164 0.9486305822349972 1.015130172035897 0.8697580651934612 0.8783229024919612 1.0771008863914413 0.916049330753445 0.841551809197489 1.0 19.74417998265615 -6.247313961490301 24.925561821777865 0.9309911004067982 0.9682091907954048 0.08447537369020863 0.06663494347576711 2541.649524635672 4484966.59191626 0.02032639232819409 0.026124483170247834 5.658300895335953e-07 6.247313961490301 0.03721809038860657 SVPPATPATPT(ph)SPATVDAAVPGAGKK ddPTM_PC-9_AZD4547_30min_R2 2 SVPPATPATPTSPATVDAAVPGAGKK 26 1 A0A0G2JHC2;Q6NYC8;Q6NYC8-3;Q6NYC8-4 A0A0G2JHC2 PPP1R18 Phostensin 1 SVPPAT(0.002)PAT(0.055)PT(0.471)S(0.471)PATVDAAVPGAGKK;SVPPAT(0.003)PAT(0.037)PT(0.773)S(0.186)PAT(0.001)VDAAVPGAGKK 133.74 4.5208e-10 20620900.0 40502.0 35674.0 42848.0 65776.0 46951.0 45064.0 35241.0 49727.0 40337.0 46250.0 True False 53380.79350606551 47204.922856907724 42279.80752361417 50612.35942906966 40432.664083252486 42246.140956148694 38377.380729136894 42042.83476278171 42469.13147038239 44630.801577404396 1.1960527622047246 1.0576758917278006 0.9473235081894543 1.1340230880973823 0.9059363187355941 0.9465691733741345 0.859885535835111 0.9420138845112539 0.9515655101270596 1.0 15.445752097440165 -1.522878745285496 0.499102703559899 0.9329174585292487 9.022040485739568 0.5667347019669713 0.0655576879793283 77.96208950262941 0.8304790322061649 0.036397108433907435 660.9091893301354 0.029999999999643673 1.522878745285496 8.08912302721032 SVPPATPATPT(ph)SPATVDAAVPGAGKK ddPTM_PC-9_Lapatinib_30min_R1 1 SVPPATPATPTSPATVDAAVPGAGKK 26 1 A0A0G2JHC2;Q6NYC8;Q6NYC8-3;Q6NYC8-4 A0A0G2JHC2 PPP1R18 Phostensin 1 SVPPATPAT(0.007)PT(0.496)S(0.496)PAT(0.001)VDAAVPGAGKK 95.361 3.8732e-09 6994700.0 8987.8 7381.4 8995.2 7266.3 9214.2 11543.0 12466.0 9358.8 13946.0 12054.0 True False 8859.63232383934 7364.308821811866 8255.649378476131 7800.687941666223 8672.238871814205 11049.33279804724 13111.428483393547 9793.64401397913 12375.254622109502 14137.5178390546 0.6266752356884593 0.5209053601664159 0.58395324217877 0.551772102463205 0.6134201894944616 0.7815610154367896 0.9274208268139897 0.6927414080373 0.8753484708555498 1.0 13.78724122419244 -6.790178358311813 2.920914409784161 0.8496695283119128 0.5691956914895061 0.7637028029312809 0.0778582590629553 0.1276094433499885 2.2327968517144483 0.027813174610117182 0.025410189365969442 1.6211441807213743e-07 6.790178358311813 -0.2804738368224067 SVPPATPATPTS(ph)PATVDAAVPGAGKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVPPATPATPTSPATVDAAVPGAGKK 26 1 A0A0G2JHC2;Q6NYC8;Q6NYC8-3;Q6NYC8-4 A0A0G2JHC2 PPP1R18 Phostensin 1 SVPPAT(0.006)PAT(0.025)PT(0.143)S(0.826)PATVDAAVPGAGKK 124.08 5.2469e-07 0.0 7979.8 6855.7 8563.6 9991.5 12368.0 12243.0 11147.0 8589.8 11107.0 9242.7 True False 9330.622531765825 7536.288588257129 8767.78870163386 9431.708647880061 9944.579184430884 11600.955527430275 10091.075462708728 8364.326851645415 11269.418862620427 10918.328344827054 0.8545834341194308 0.6902419812120519 0.8030339832917656 0.8638418217518314 0.9108151788769461 1.062521217630045 0.9242326429475565 0.7660812706377632 1.032156068832617 1.0 13.414464368294398 -5.957586364671408 2.08703429354532 0.942128867792885 0.769389567138972 0.43987885844678576 0.08481603605907742 0.3131960346406125 2.755928256155979 0.02733452924209318 0.04456270103296363 1.1025889489975342e-06 5.957586364671408 -0.17273930065391296 SVPPATPATPTS(ph)PATVDAAVPGAGKK ddPTM_PC-9_Lapatinib_30min_R1 1 SVPPATPATPTSPATVDAAVPGAGKK 26 1 A0A0G2JHC2;Q6NYC8;Q6NYC8-3;Q6NYC8-4 A0A0G2JHC2 PPP1R18 Phostensin 1 SVPPAT(0.001)PAT(0.008)PT(0.187)S(0.803)PAT(0.002)VDAAVPGAGKK 130.17 1.4549e-10 4550800.0 22678.0 16488.0 20128.0 17253.0 21764.0 26831.0 21817.0 21848.0 23988.0 20950.0 True False 22354.607561364133 16449.823049019695 18473.15353632687 18521.843174320813 20483.884309670328 25683.500676115855 22946.577508599155 22863.137840045303 21286.218835161526 24571.179585879727 0.909789759308528 0.669476326585187 0.7518220064185605 0.7538035815327615 0.8336549019991601 1.0452693402996145 0.933881803614582 0.9304859687397352 0.8663083821744576 1.0 14.58467949821207 -6.55716052471993 6.0338623765255965 0.9494801887098279 0.7658630690437904 0.6055556372081186 0.0704844973230676 0.12179489814578875 12.509164126669411 0.022995624000303007 0.02329438849009418 2.7722952144300025e-07 6.55716052471993 -0.18361711966603744 SVPSIAAATGTHS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 SVPSIAAATGTHSR 14 0 Q8IY63-2;Q8IY63 Q8IY63-2 AMOTL1 Angiomotin-like protein 1 1 SVPSIAAAT(0.046)GT(0.267)HS(0.687)R 57.61600000000001 0.037663999999999996 1779700.0 31942.0 25742.0 28356.0 18920.0 21248.0 23075.0 17875.0 17969.0 22782.0 14546.0 True False 31486.501222554616 25682.39598058375 26024.679137325384 20311.439915269795 19998.234415175295 22088.136040452227 18800.480036953275 18803.905339059613 20216.05125490453 17060.25671867333 1.8456053588039516 1.5053932894499207 1.5254564785558025 1.19057059047874 1.1722118104639188 1.2947129931682462 1.102004521208358 1.1022052979119459 1.1849793111716205 1.0 14.058351735699809 -1.5228787452803854 0.3714742039287712 1.0806520286959007 11.40185235693524 0.892679535233579 0.08024471713379702 19.428642199482628 0.26797151413532333 0.06228204483920885 143.2740683781276 0.0299999999999967 1.5228787452803854 10.321200328239339 SVPT(ph)STVFYPSDGVATEK ddPTM_PC-9_AZD4547_30min_R2 1 SVPTSTVFYPSDGVATEK 18 0 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 1 SVPT(0.82)S(0.144)T(0.035)VFYPS(0.001)DGVATEK 177.67 6.0791e-33 0.0 5959.7 10071.0 7004.9 14226.0 9051.9 10851.0 5333.8 9799.5 9350.6 7905.4 True False 7854.760630539198 13326.253800861075 6912.01044907965 10946.415489509027 7795.199932167438 10172.485254641611 5808.497867060254 8285.212445107869 9844.85362637176 7628.63435221649 1.0296417770052129 1.746872793423262 0.9060613118875431 1.4349115430245467 1.0218342592213183 1.3334608509170465 0.7614072976734824 1.0860675794089687 1.2905132389142953 1.0 12.897209099307185 -6.322238304771916 1.0116759065178322 1.0624047136558799 1.3123681471799082 0.09951764168242017 0.26119353032276654 1.1554505525181544 2.5064085830370426 0.11669359874994202 0.16912728330043095 4.7616963272756297e-07 6.322238304771916 0.2499634335240284 SVPTAYRVS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 SVPTAYRVSR 10 1 Q12872;Q12872-2 Q12872 SFSWAP Splicing factor, suppressor of white-apricot homolog 1 SVPT(0.001)AYRVS(0.999)R;SVPTAYRVS(1)R 82.774 0.006819499999999999 15286900.0 27563.0 29008.0 37440.0 35895.0 32439.0 39561.0 35846.0 43566.0 38968.0 26921.0 True False 36327.460653984584 38384.26871764254 36943.52113713857 27619.96232222173 27935.404787898628 37087.244416079324 39036.2245570966 36833.87574708603 41027.768925251294 25978.503984114654 1.3983661521155382 1.477539612793476 1.4220803923016048 1.063185252665465 1.0753276941959622 1.4276127847376219 1.502635585981644 1.4178597724337485 1.5792968274978025 1.0 14.665030732704674 SVPTAYRVS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVPTAYRVSR 10 1 Q12872;Q12872-2 Q12872 SFSWAP Splicing factor, suppressor of white-apricot homolog 1 SVPTAYRVS(1)R 77.74 0.010074 5496100.0 10826.0 14255.0 14710.0 12671.0 15015.0 14630.0 13155.0 10394.0 11208.0 10919.0 True False 12658.627976753407 15670.142191987014 15060.742187985663 11961.084949936265 12072.91853607937 13862.777045356928 11908.863166047664 10121.168513353328 11371.89579654719 12898.528265243562 0.9814009564845788 1.214878307799802 1.1676326072462402 0.9273216838363384 0.9359919432522482 1.0747564962672242 0.923273021631262 0.7846762285760833 0.8816428946541099 1.0 13.65491884166594 -6.2044123158954125 0.8490565103294676 0.8964265465400842 1.1311201104264372 0.37942688963507865 0.09797181013166306 0.6627085199508115 1.014850981962448 0.052858211841951885 0.09468603322388137 6.245794402102919e-07 6.2044123158954125 0.23469356388635298 SVPTAYRVS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 SVPTAYRVSR 10 1 Q12872;Q12872-2 Q12872 SFSWAP Splicing factor, suppressor of white-apricot homolog 1 SVPTAY(0.001)RVS(0.999)R 70.54 0.016753999999999998 9677000.0 31080.0 21154.0 23143.0 19927.0 19368.0 19365.0 16811.0 19071.0 19933.0 16592.0 True False 30636.79350062605 21105.019212697895 21240.271874563445 21392.498054523305 18228.81231895308 18536.80409201981 17681.39132314527 19957.10828210839 17687.935636204544 19459.9050925497 1.574354723464477 1.0845386507449122 1.091488975590912 1.099311530697727 0.9367369590066528 0.9525639515640134 0.9086062464875361 1.025550134350298 0.9089425437627874 1.0 14.248217053551219 -1.6855771876849246 0.8924641499027908 0.9692384092795133 199.99999994688017 0.8908899918461887 0.061347567345589604 186.4181052388961 0.5918661541062403 0.020713484784502932 75299.72223856657 0.020626370397487197 1.6855771876849246 199.03076153760065 SVPTSTVFYPSDGVATEK ddPTM_PC-9_Lapatinib_30min_R1 2 SVPTSTVFYPSDGVATEK 18 0 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 ; 217.2 6.505e-27 46053000.0 138512.0 129840.0 147572.0 134128.0 128761.0 120622.0 143685.0 126466.0 127210.0 131655.0 False True 136536.79348001027 129539.36345734597 135439.19980439363 143992.22055789124 121187.53113386602 115463.27824361558 151124.3062438954 132342.0720468315 112882.27021931387 154411.39133073922 0.8842404197210896 0.8389236204722813 0.8771321768242578 0.932523302309149 0.7848354327323569 0.7477639910406655 0.9787121593911223 0.857074539036847 0.7310488510366916 1.0 17.23641966234173 -11.213507295826721 6.452413199642572 1.0015091353096266 0.8504037852794136 0.27625742080289284 0.07370346557264776 0.0016290047505328428 7.8105141796682e-05 0.07265337362547561 0.017453783751802534 6.1163552784296654e-12 11.213507295826721 -0.15110535003021297 SVPVNNLPERSPTDS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 SVPVNNLPERSPTDSPR 17 1 P49454 P49454 CENPF Centromere protein F 1 SVPVNNLPERS(0.125)PT(0.272)DS(0.603)PR 166.9 7.393600000000001e-24 0.0 9961.9 8173.3 9755.7 8918.4 12771.0 10037.0 8259.0 10084.0 12490.0 10682.0 True False 9819.841479211278 8154.375226016058 8953.624004091029 9574.288886910252 12019.834888752055 9607.740907389767 8686.610608402632 10552.53945345189 11083.244674469208 12528.369467129693 0.7838084201599659 0.6508728248644365 0.7146679404356955 0.7642086954754987 0.9594093565238586 0.7668787971648912 0.6933552391788439 0.8422915273322894 0.8846518059311697 1.0 13.612911043630127 -14.52287874528001 0.08343365839170862 1.7543821456846262 0.5693411368768209 0.48181992335209256 0.07804216204288023 223.98976283935843 1.310087666419653 30.32149332590111 2.5495380640889387 3.0000000000022587e-15 14.52287874528001 -1.1850410088078054 SVPVT(ph)PARPPPHNK ddPTM_PC-9_AZD4547_30min_R2 1 SVPVTPARPPPHNK 14 1 Q99618;F5GX58;F8WDL1;J3KMY0 Q99618 CDCA3 Cell division cycle-associated protein 3 1 S(0.014)VPVT(0.986)PARPPPHNK 58.723 0.038851 5911900.0 21927.0 25103.0 26117.0 31577.0 30590.0 24124.0 21989.0 36048.0 26820.0 29723.0 True False 28899.32989006712 33217.053834079554 25770.671515455346 24297.41050978675 26343.106521835394 22615.522466406263 23945.978401662604 30477.609900632542 28237.650445884803 28682.40681697708 1.0075629313284005 1.1580985530969605 0.8984835784492715 0.8471189557009262 0.9184412831855848 0.7884806393939077 0.8348664236743553 1.062588997328944 0.9844937569594394 1.0 14.807878469043521 -2.3680521145828743 13.239227647871314 0.9446801052466449 1.1540921904861876 0.0 0.10809611404407032 0.0 0.0 0.027033887444888365 0.0 0.00428497098405294 2.3680521145828743 0.2094120852395427 SVQAGNPGGPGPGGR ddPTM_PC-9_Lapatinib_30min_R1 1 SVQAGNPGGPGPGGR 15 0 Q96AE4;E9PEB5;Q96AE4-2 Q96AE4 FUBP1 Far upstream element-binding protein 1 0 164.9 0.0013575999999999998 2186000.0 6096.5 3962.1 4874.9 4852.9 4832.3 5008.5 5124.7 4181.4 3996.6 5664.2 False True 6009.562792038823 3952.926000880697 4474.104539658182 5209.798454799829 4548.073614667334 4794.298130383749 5390.031890650319 4375.683108951185 3546.4608219362403 6643.249422927918 0.9046119465721029 0.5950289909690762 0.6734813424612144 0.7842244243937607 0.6846158145094656 0.7216796819094488 0.8113547373439938 0.6586660879914192 0.5338442975957371 1.0 12.697673366543102 -10.800081638153262 4.800865775595993 1.000099333028301 0.7068109720826502 0.4287111966986351 0.10129296440282316 0.00010485113977941561 1.578584963815046e-05 0.09548638698846952 0.023151035127732346 1.5845952941491928e-11 10.800081638153262 -0.2932883609456508 SVQEGENPDDGVRGS(ph)PPEDYR ddPTM_PC-9_AZD4547_30min_R2 1 SVQEGENPDDGVRGSPPEDYR 21 1 H7C5M1;Q5TCT4;A2A2V2;P42696-2;P42696 H7C5M1 RBM34 RNA-binding protein 34 1 SVQEGENPDDGVRGS(0.997)PPEDY(0.003)R 73.346 0.0008577999999999999 20383000.0 39612.0 38738.0 44205.0 65837.0 55390.0 41653.0 28441.0 56163.0 42619.0 45275.0 True False 52207.7920192155 51259.30093712204 43618.8128169661 50659.296821510296 47700.05460099581 39048.431325369726 30972.193902482417 47484.29884734869 44871.75333158704 43689.936030637495 1.1949615120197217 1.1732519109475588 0.9983720916043108 1.1595186769324988 1.0917858649998076 0.893762611553999 0.7089091153798719 1.0868475251154044 1.027050103715437 1.0 15.415013372986659 -6.6775014572209725 5.4684520370769585 0.9345027784918485 1.1244248142036062 0.41821211702814964 0.1065144266652297 0.2191724868576845 10.810616376354085 0.03788688757192937 0.03757786214658645 2.101350718214646e-07 6.6775014572209725 0.1899220357117577 SVQEGENPDDGVRGS(ph)PPEDYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVQEGENPDDGVRGSPPEDYR 21 1 H7C5M1;Q5TCT4;A2A2V2;P42696-2;P42696 H7C5M1 RBM34 RNA-binding protein 34 1 SVQEGENPDDGVRGS(0.977)PPEDY(0.023)R 50.505 0.0198 11766000.0 11568.0 12244.0 15907.0 22327.0 18242.0 14421.0 4814.5 10598.0 11746.0 3466.0 True False 13526.233921585384 13459.503402223008 16286.28320763343 21076.090575110644 14667.611051292693 13664.737373280403 4358.4357060385 10319.813729509196 11917.763028751193 4094.3583631590977 3.3036272650909098 3.287329102242534 3.977737599663203 5.1475930306327395 3.58239551849476 3.337455142235536 1.0644978576510453 2.520495963999278 2.9107767253562447 1.0 11.999421665998968 -7.064337795458881 4.776824574996401 2.0027520769515736 3.874532381482748 0.6196864465484981 0.7343146423276629 0.16240662642654932 7.323258081287118 0.2975007919587535 0.23282661854369302 8.623075816199427e-08 7.064337795458881 1.8717803045311743 SVQEGENPDDGVRGS(ph)PPEDYR ddPTM_PC-9_Lapatinib_30min_R1 1 SVQEGENPDDGVRGSPPEDYR 21 1 H7C5M1;Q5TCT4;A2A2V2;P42696-2;P42696 H7C5M1 RBM34 RNA-binding protein 34 1 SVQEGENPDDGVRGS(0.989)PPEDY(0.011)R 79.695 0.00045132 20585000.0 31847.0 23846.0 27184.0 24446.0 16457.0 19647.0 18714.0 12017.0 17494.0 16089.0 True False 31392.855939975467 23790.786052093863 24949.03645327453 26243.84038946541 15489.03161570688 18806.74360939393 19682.919351694745 12575.353690215326 15523.641500013162 18869.962212755076 1.663641696047255 1.2607755004412555 1.32215614276166 1.3907733409092888 0.8208300282253417 0.9966497758369429 1.0430820756169905 0.6664217738451572 0.8226641540129856 1.0 14.20380391348275 -5.97367525121784 0.7430908132492383 0.8380224062282035 1.5558408184285215 0.7157610695365468 0.15490357976550256 0.47235335213880325 0.5078301981787396 0.08326946425030232 0.21820871312150558 1.0624897493747627e-06 5.97367525121784 0.7178184122003181 SVRPTDSNVSPAIS(ph)IHEIGAVGATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVRPTDSNVSPAISIHEIGAVGATK 25 1 A6NIT2;A6NMN0;P46020-3;P46020-2;P46020 A6NIT2 PHKA1 Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform 1 S(0.028)VRPT(0.016)DS(0.015)NVS(0.04)PAIS(0.901)IHEIGAVGATK 49.745 0.012785 3086200.0 13390.0 9826.0 11425.0 15882.0 16290.0 14848.0 13532.0 13705.0 16390.0 11522.0 True False 15656.662535445055 10801.460342228302 11697.415329553778 14992.18303013873 13098.091438743446 14069.34474158987 12250.15099680403 13345.258271647814 16629.672743166364 13610.847391898184 1.1503076983116156 0.7935920542800178 0.8594185940631903 1.101487849982271 0.9623274041365012 1.0336861722485116 0.9000285319557617 0.9804869518698401 1.2217955476501137 1.0 13.732469269318027 -8.11208736505903 8.630139798579549 1.110055269234098 0.9655300005537342 0.19301638729860193 0.11269595889907429 0.4818425555906003 33.81544552387781 0.0742784261994692 0.02795070943612548 7.725251640661241e-09 8.11208736505903 -0.14452526868036375 SVS(ph)ANPK ddPTM_PC-9_AZD4547_30min_R2 1 SVSANPK 7 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 S(0.004)VS(0.996)ANPK 71.34899999999999 0.041643 15107000.0 81616.0 70896.0 62915.0 63055.0 51209.0 46199.0 43535.0 56819.0 81995.0 130360.0 True False 107568.19028174017 93811.7455531572 62080.705992069255 48518.64394003877 44099.51428168255 43310.16922672452 47409.53066152988 48038.929120729044 86329.08830388979 125796.13607849587 0.8550993189060943 0.7457442531829385 0.493502486859623 0.38569264090721744 0.3505633452379235 0.34428854952825655 0.3768758893512173 0.3818792104294293 0.6862618439251669 1.0 16.94072808388769 -8.567128577703949 4.123061034088684 0.9996706329060712 0.4844553587468432 0.47147032365841 0.16602827345961674 0.2280507903037807 12.230181678745694 0.1802846086481047 0.047178593587097736 2.709389368328536e-09 8.567128577703949 -0.515215274159228 SVS(ph)ANPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVSANPK 7 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 S(0.002)VS(0.998)ANPK 74.376 0.034272000000000004 16935000.0 39494.0 69070.0 53763.0 36154.0 128690.0 131280.0 57234.0 80876.0 105760.0 143590.0 True False 46179.55415794374 75926.81313227236 55044.913817312896 34128.40859284947 103474.1183088947 124395.445694768 51812.381181723445 78753.09069520538 107306.53992173742 169621.7303421851 0.27225022445404706 0.4476243284342283 0.32451569563798494 0.20120304470424152 0.6100286684975562 0.7333697483442705 0.30545839307970823 0.4642865659743798 0.6326225991520272 1.0 17.371961480709807 -14.522878732017217 0.12935789527379413 2.9037785950034642 0.20472693146341317 0.6224071534446508 0.14384199398809258 105.10124445147336 0.8560959531637264 51.580419204793394 1.1885836268785115 3.0000000916183925e-15 14.522878732017217 -2.699051663540051 SVS(ph)ANPK ddPTM_PC-9_Lapatinib_30min_R1 1 SVSANPK 7 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 S(0.074)VS(0.926)ANPK 75.378 0.032806 20830000.0 30081.0 45259.0 26547.0 41165.0 42252.0 23133.0 70232.0 65339.0 39331.0 36998.0 True False 29652.039423820213 45154.20556620468 24364.40813438342 44192.41142241444 39766.82043062813 22143.655515656814 73868.26931218481 68374.88847174667 34901.12860620886 43393.055003263864 0.6833360642985358 1.0405860007507732 0.5614817424712507 1.0184212985025012 0.9164328353382131 0.5103041377010964 1.7023062632172066 1.575710409571388 0.8043021770092871 1.0 15.405176539405568 -7.255400934592235 24.995872549801582 1.3185555808665064 0.805845830212262 0.39041690382853234 0.29221836443524296 482.8565762948005 1998768.3374918005 0.1117403564152043 0.08426679463007591 5.553912910522725e-08 7.255400934592235 -0.5127097506542444 SVS(ph)CDNVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVSCDNVSK 9 0 Q96CB8;A0A087WXN4 Q96CB8 INTS12 Integrator complex subunit 12 1 S(0.052)VS(0.948)CDNVSK;S(0.26)VS(0.739)CDNVS(0.001)K 125.97 0.0014095000000000002 87283000.0 192558.0 214001.0 174370.0 231645.0 205335.0 177283.0 245676.0 249242.0 183331.0 154786.0 True False 225154.2662061412 235245.6049966616 178527.6421019078 218666.68165322236 165101.08075963083 167985.96739111503 222403.79073978894 242699.66159372762 186011.86904682306 182847.476514698 1.2313774873892909 1.2865674138945615 0.9763746566530113 1.1958966337478825 0.90294426757571 0.918721825387684 1.2163350294960797 1.32733394094295 1.0173061865137127 1.0 17.480281190561797 -5.245589727087494 24.590018068394155 1.079498902830526 1.258972486711724 0.2467793308528271 0.13155271552997413 1044.6282689590396 1620685.0625183787 0.03563792987434887 0.09355699757164788 5.680810114810648e-06 5.245589727087494 0.17947358388119805 SVS(ph)CDNVSK ddPTM_PC-9_Lapatinib_30min_R1 2 SVSCDNVSK 9 0 Q96CB8;A0A087WXN4 Q96CB8 INTS12 Integrator complex subunit 12 1 S(0.004)VS(0.996)CDNVSK;S(0.182)VS(0.818)CDNVSK 112.43 0.0021686 188614000.0 87104.0 89191.0 80916.0 74326.0 88030.0 90359.0 78888.0 86959.0 82803.0 69606.0 True False 85861.88098708258 88984.48371937878 74263.39882479249 79792.18198426739 82852.248473639 86494.55620711697 82972.43463805142 90999.4325994371 73476.8541857545 81637.30435583492 1.051748115210099 1.0899978192753585 0.9096748038261826 0.9773985387424707 1.0148822174787702 1.0594979450829318 1.0163544141094742 1.1146795367323155 0.9000401809629675 1.0 16.31694092526311 SVS(ph)CIEVTPGDR ddPTM_PC-9_AZD4547_30min_R2 2 SVSCIEVTPGDR 12 0 Q96JZ2-2;Q96JZ2 Q96JZ2-2 HSH2D Hematopoietic SH2 domain-containing protein 1 SVS(1)CIEVTPGDR;S(0.429)VS(0.571)CIEVTPGDR 145.31 0.00010842 14805100.0 18277.9 17096.4 31148.0 41325.0 37099.0 28696.0 25983.0 34877.0 31419.0 26309.0 True False 24089.891996062284 22622.47696167621 30734.957168258356 31798.15971488546 31948.44422535374 26901.63458365088 28295.436664259363 29487.561043729485 33079.74419684021 25387.929917836373 0.9488718487101957 0.8910721368339178 1.2106129671748231 1.252491235709043 1.2584107616788502 1.059623004739392 1.1145231909743185 1.161479535320952 1.3029713058093773 1.0 14.631855144797768 -5.260657270557015 24.965875632653322 1.1759594226127765 0.9199719725726853 0.5545118653304266 0.08952016508130382 46.41856682751852 1481674.9559358621 0.023321172381898035 0.05473772714077406 5.4870981597530235e-06 5.260657270557015 -0.25598745004009127 SVS(ph)CIEVTPGDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVSCIEVTPGDR 12 0 Q96JZ2-2;Q96JZ2 Q96JZ2-2 HSH2D Hematopoietic SH2 domain-containing protein 1 S(0.008)VS(0.992)CIEVTPGDR;SVS(1)CIEVTPGDR 143.42 8.4408e-05 8503100.0 26606.0 29724.0 33284.0 36353.0 39607.0 32742.0 31251.0 35856.0 30201.0 26989.0 True False 31109.870307546753 32674.80228092753 34077.616790272936 34316.259268016176 31846.29267122847 31024.951881003206 28290.67904235315 34914.817992572345 30642.632490321354 31881.892055193548 0.9757849456892245 1.0248702374489351 1.0688705905934999 1.0763557949637457 0.9988833980146646 0.9731214141021863 0.8873588491353231 1.0951300484967528 0.9611296731471645 1.0 14.9604496292557 -6.478760182322135 9.190661618505828 0.9835760717081197 1.0379807559827237 0.17867614742752502 0.053900043038045284 0.8175493210849862 164.83563931807728 0.017141282813799858 0.01929810289018705 3.3207778048541556e-07 6.478760182322135 0.05440468427460399 SVS(ph)CIEVTPGDR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSCIEVTPGDR 12 0 Q96JZ2-2;Q96JZ2 Q96JZ2-2 HSH2D Hematopoietic SH2 domain-containing protein 1 S(0.002)VS(0.996)CIEVT(0.002)PGDR 101.39 0.0027362 4552500.0 23796.0 26079.0 22862.0 22052.0 28962.0 29111.0 28880.0 33598.0 28823.0 30024.0 True False 23456.66467634806 26018.615677788992 20982.374609872077 23673.77764331551 27258.512101482793 27865.99039105545 30375.26508907474 35159.08573552923 25576.65022035436 35213.60839553474 0.6661249938623864 0.7388795656933664 0.5958598270926629 0.6722905922449418 0.7740902833729276 0.7913415199616122 0.862600184221009 0.9984516593871015 0.7263285810720155 1.0 15.10384544962497 -6.8098225454842085 1.2799657902404251 0.9007897751559145 0.6676818037318437 0.6156624301964715 0.07989609182733533 0.29330464163823994 1.0068496338005009 0.03855983591436584 0.03326388522608784 1.5494496010791012e-07 6.8098225454842085 -0.2331079714240708 SVS(ph)EAALAQPQGPLGTDSLK ddPTM_PC-9_AZD4547_30min_R2 2 SVSEAALAQPQGPLGTDSLK 20 0 M0R201;M0QY29;Q05469-2;Q05469 M0R201 LIPE Hormone-sensitive lipase 1 S(0.006)VS(0.994)EAALAQPQGPLGTDSLK;S(0.027)VS(0.973)EAALAQPQGPLGTDSLK 155.88 1.8944e-05 18203000.0 30274.0 35581.0 51720.0 68113.0 58347.0 51382.0 51769.0 64432.0 43568.0 50636.0 True False 39900.50226168156 47081.862425621875 51034.159006752336 52410.600185359785 50246.52619253124 48169.075417380474 56376.3407101583 54475.51490006533 45870.915534165164 48863.24905239887 0.8165748908529181 0.963543426576757 1.0444282768021724 1.0725975288535743 1.0283091519077867 0.9857935432358583 1.15375751313022 1.1148565835572684 0.9387610612011319 1.0 15.576462175122305 -4.795533376427456 1.916266943671744 1.0496012930748322 0.7480913375529689 0.5750737793389502 0.05917179140438304 0.5475435234370849 2.2008131274648255 0.016270039883610955 0.2954535133063747 1.6012775821277357e-05 4.795533376427456 -0.3015099555218633 SVS(ph)EAALAQPQGPLGTDSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SVSEAALAQPQGPLGTDSLK 20 0 M0R201;M0QY29;Q05469-2;Q05469 M0R201 LIPE Hormone-sensitive lipase 1 S(0.022)VS(0.978)EAALAQPQGPLGTDSLK;S(0.012)VS(0.988)EAALAQPQGPLGTDSLK;S(0.014)VS(0.986)EAALAQPQGPLGTDSLK;S(0.015)VS(0.985)EAALAQPQGPLGTDSLK 218.14 1.3635e-28 21885300.0 95976.0 94058.6 101839.0 127245.0 138552.0 107914.0 116321.0 105446.0 110121.0 96898.9 True False 112222.84118759313 103396.11619636814 104267.2279865584 120115.87518385625 111403.73020385414 102254.79986826032 105302.23278888878 102678.15422927191 111731.31129653558 114465.90351872974 0.9804041005907966 0.9032918364152842 0.9109020658671291 1.0493594292400097 0.9732481619351867 0.8933210390597114 0.9199441017093659 0.8970195584265926 0.9761099843872135 1.0 16.80455839459256 -6.725036468552311 24.999802400472866 0.929759135739145 0.9619539032210048 0.056354144505460835 0.048716897320619894 464.9492903266606 319303.93179185246 0.016622801609869713 0.016622337096732033 1.88349092245311e-07 6.725036468552311 0.03219476748185979 SVS(ph)EAALAQPQGPLGTDSLK ddPTM_PC-9_Lapatinib_30min_R1 2 SVSEAALAQPQGPLGTDSLK 20 0 M0R201;M0QY29;Q05469-2;Q05469 M0R201 LIPE Hormone-sensitive lipase 1 S(0.011)VS(0.989)EAALAQPQGPLGTDSLK;S(0.001)VS(0.999)EAALAQPQGPLGTDSLK 197.84 1.3513e-15 19011800.0 88996.0 71815.0 76563.0 61538.0 74728.0 66279.0 65074.0 62645.0 68943.0 49659.0 True False 87726.90072013254 71648.71677980063 70268.2856817268 66063.7098047501 70332.64596090076 63444.40167389525 68443.2133104726 65555.71539681603 61177.913338024904 58242.4919835418 1.5062353572529568 1.2301794504267978 1.2064780075272752 1.1342871425113203 1.2075830474557203 1.089314682686026 1.1751422540404577 1.1255650842573977 1.050399995853759 1.0 15.829784464059006 -1.5228787452803405 0.6795206089165436 1.1111493242840567 42.25397722553821 0.8163987407456492 0.05625207269991525 103.08785742500241 0.5938753183784383 0.02171020347508486 6419.838490199191 0.029999999999999798 1.5228787452803405 41.14282790125415 SVS(ph)EESANSLVSVGVEAK ddPTM_PC-9_AZD4547_30min_R2 2 SVSEESANSLVSVGVEAK 18 0 Q8NEZ4;Q8NEZ4-3;H0YMU7;C9J4Z5 Q8NEZ4 KMT2C Histone-lysine N-methyltransferase 2C 1 S(0.414)VS(0.586)EESANSLVSVGVEAK;S(0.027)VS(0.972)EES(0.001)ANSLVSVGVEAK 154.39 1.7954e-05 9352400.0 46201.0 52630.0 72276.0 90358.0 79621.0 75986.0 70518.0 87889.0 68129.0 63345.0 True False 60891.956959501564 69641.61826425557 71317.57301570062 69527.35911718367 68566.99850850136 71234.58340790673 76793.96538853251 74307.7745383014 71730.15985188985 61127.3108307174 0.9961497754765033 1.1392881073587096 1.166705553483345 1.1374189077240597 1.1217080806709627 1.165347901614384 1.2562954977882388 1.2156231564657776 1.173455185204129 1.0 15.899529479671585 -4.74622142974378 3.1234038664781982 1.164274052998587 0.9621250776625857 0.34600272203559435 0.06381806962377377 0.4425129837007518 5.9815075914512095 0.016058602376121466 0.23278469031341087 1.7938187956990897e-05 4.74622142974378 -0.2021489753360014 SVS(ph)EESANSLVSVGVEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVSEESANSLVSVGVEAK 18 0 Q8NEZ4;Q8NEZ4-3;H0YMU7;C9J4Z5 Q8NEZ4 KMT2C Histone-lysine N-methyltransferase 2C 1 S(0.029)VS(0.971)EESANSLVSVGVEAK 209.45 2.9229999999999997e-67 0.0 12437.0 16227.0 11234.0 15897.0 19309.0 15530.0 15693.0 11995.0 19302.0 13958.0 True False 14542.338458053033 17837.909319493036 11501.861165182254 15006.342628769384 15525.540060816289 14715.579460997478 14206.445432518884 11680.14395975304 19584.255234203607 16488.47490853279 0.8819698934391663 1.0818410688948505 0.6975697406210709 0.9101110146338397 0.9415995200855004 0.8924766870574647 0.861598511161699 0.7083823109503332 1.1877541945415917 1.0 14.009170343294597 -8.273938818928759 24.99970070070449 1.0938770984863018 0.8770614228096476 0.38417814844384435 0.11224470157035599 904.8573579366484 1809755.1810380346 0.1026940773393074 0.027255668483718867 5.321832250972754e-09 8.273938818928759 -0.21681567567665416 SVS(ph)EESANSLVSVGVEAK ddPTM_PC-9_Lapatinib_30min_R1 2 SVSEESANSLVSVGVEAK 18 0 Q8NEZ4;Q8NEZ4-3;H0YMU7;C9J4Z5 Q8NEZ4 KMT2C Histone-lysine N-methyltransferase 2C 1 S(0.001)VS(0.999)EESANSLVSVGVEAK;S(0.001)VS(0.999)EESANSLVSVGVEAK 301.82 3.5044999999999994e-122 7396000.0 69177.0 60664.0 61420.0 49551.0 68786.0 67510.0 71839.0 63338.0 71817.0 62862.0 True False 68190.52329449184 60523.53623518504 56370.28468805627 53195.14583729033 64740.142718479176 64622.75467349634 75558.4719090734 66280.914706737 63728.21319346319 73727.61294165003 0.9248980208875013 0.8209073075929497 0.7645749324973968 0.7215091295494723 0.8780989935170724 0.8765068078989684 1.024832744400288 0.8989971607950126 0.8643737488680038 1.0 16.169917427540568 -6.716241849895462 2.4742151029159185 0.9372160499830533 0.8067873724423547 0.4337908825409622 0.06725381287414477 0.28526743788600134 3.575522478611668 0.026143235118777475 0.024867401514147763 1.9220210957920668e-07 6.716241849895462 -0.13042867754069865 SVS(ph)EINSDDELSGK ddPTM_PC-9_AZD4547_30min_R2 1 SVSEINSDDELSGK 14 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 S(0.001)VS(0.964)EINS(0.035)DDELSGK 171.08 5.1289e-19 0.0 6117.4 6431.2 8931.2 10273.0 9148.4 10852.0 8635.4 9239.8 8690.9 9020.6 True False 8062.605950175422 8509.959631029464 8812.766452457588 7904.718566267828 7878.302572878689 10173.42272448353 9403.93387101356 7812.001219481376 9150.283231175996 8704.791539656955 0.9262261954745397 0.9776178547481713 1.0124040779504857 0.9080882098388933 0.9050535600981391 1.1687152619492196 1.08031695281518 0.897436909763061 1.0511777553189512 1.0 13.087594033623565 SVS(ph)ENSLVAMDFSGQTGR ddPTM_PC-9_AZD4547_30min_R2 2 SVSENSLVAMDFSGQTGR 18 0 A0A2R8YCL1;Q13322-3;Q13322-2;Q13322-4;Q13322 A0A2R8YCL1 GRB10 Growth factor receptor-bound protein 10 1 S(0.016)VS(0.981)ENS(0.003)LVAMDFSGQTGR;S(0.032)VS(0.723)ENS(0.245)LVAMDFSGQTGR 109.77 0.00021223 26569000.0 126927.0 118588.0 197387.0 290150.0 248460.0 235787.0 191004.0 258270.0 211383.0 230185.0 True False 167287.1457543917 156919.25188526604 194769.51940962518 223260.4002728131 213965.61773178267 221043.2016160887 208002.98597622235 218360.30595418223 222556.27383305272 222126.29321286117 0.7531172619626902 0.706441590572495 0.8768413526938016 1.0051056857949956 0.963261100867252 0.995123982932833 0.9364176701805192 0.983045738511154 1.0019357484157876 1.0 17.76102065004406 -5.466902372383194 3.095657005799384 0.9801235750583958 0.7300030882628867 0.9460947446080497 0.024060132624440806 0.0494943291768725 0.9297733224511426 0.0065526033657298905 0.014817440910942592 3.4126961900933594e-06 5.466902372383194 -0.250120486795509 SVS(ph)ENSLVAMDFSGQTGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVSENSLVAMDFSGQTGR 18 0 A0A2R8YCL1;Q13322-3;Q13322-2;Q13322-4;Q13322 A0A2R8YCL1 GRB10 Growth factor receptor-bound protein 10 1 S(0.025)VS(0.945)ENS(0.03)LVAMDFSGQTGR;S(0.04)VS(0.952)ENS(0.007)LVAMDFSGQTGR 79.92 0.0033554 17884900.0 53480.0 58221.0 63934.0 92477.0 106479.0 119165.0 128138.0 126614.0 128846.0 105151.0 True False 62533.10772185224 64000.796110815514 65458.42903104521 87295.81350447907 85615.20431589728 112915.77762200688 115999.84100121768 123290.51665862235 130730.1289973162 124214.04392514174 0.5034302543079441 0.5152460550224573 0.5269809029846423 0.7027853755175087 0.6892554304688264 0.9090419573655952 0.9338705780412849 0.9925650334105863 1.0524585213255067 1.0 16.922468771632325 -6.529437285312159 0.7659085094441683 1.0324934667395533 0.48262363376367634 0.9665272792246569 0.0380653282772579 0.10354018376310054 0.13511832271795432 0.023094001207941906 0.029151068853734273 2.955035582258596e-07 6.529437285312159 -0.549869832975877 SVS(ph)ENSLVAMDFSGQTGR ddPTM_PC-9_Lapatinib_30min_R1 3 SVSENSLVAMDFSGQTGR 18 0 A0A2R8YCL1;Q13322-3;Q13322-2;Q13322-4;Q13322 A0A2R8YCL1 GRB10 Growth factor receptor-bound protein 10 1 S(0.031)VS(0.875)ENS(0.094)LVAMDFSGQTGR;S(0.022)VS(0.97)ENS(0.008)LVAMDFSGQTGR;S(0.12)VS(0.88)ENSLVAMDFSGQTGR 125.59 3.8947e-05 10825200.0 80729.4 79364.0 92985.6 75788.4 109190.5 104509.3 96549.9 98503.0 116178.5 83047.5 True False 79578.18395204138 79180.23753410944 85340.6829027961 81362.13175869106 102768.12946678272 100039.6808620774 101548.78139971096 103079.80898288083 103093.25391615868 97402.14972116194 0.8170064436960978 0.8129208416937687 0.8761683715103331 0.8353217253583267 1.0550909785973126 1.0270787775061028 1.0425722809036535 1.0582909030034 1.0584289382861563 1.0 16.571665993313275 -6.259560018245662 24.999389313954897 1.0426163842166611 0.8366672301992348 0.9507088395849548 0.02285061890891223 33.458280681068466 445064.1276924019 0.0069613090661669805 0.008530599259498603 5.500978933141191e-07 6.259560018245662 -0.2059491540174263 SVS(ph)GFLHFDTATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVSGFLHFDTATK 13 0 Q92621 Q92621 NUP205 Nuclear pore complex protein Nup205 1 S(0.411)VS(0.589)GFLHFDTATK 78.763 0.008293 3753500.0 27117.0 37547.0 31313.0 24491.0 30480.0 21118.0 28405.0 14829.0 22268.0 25391.0 True False 31707.372514836727 41274.41802052167 32059.620675213784 23118.848670893312 24507.66280251078 20010.5349038857 25714.272765608817 14439.754462624254 22593.627373082887 29994.18730495459 1.0571172404994331 1.376080558572219 1.068861121298593 0.7707776322072385 0.8170804080583467 0.6671470942164937 0.8573085346226802 0.4814184267042642 0.7532668627881363 1.0 14.872395321642706 -5.671968878823992 3.1078515569785754 0.7405099428250427 1.2204369484488398 0.6233711583642951 0.14573717769579608 0.14098494094331712 2.71079385210459 0.03956877955509154 0.07370341608339942 2.1282915520946613e-06 5.671968878823992 0.4799270056237971 SVS(ph)GFLHFDTATK ddPTM_PC-9_Lapatinib_30min_R1 1 SVSGFLHFDTATK 13 0 Q92621 Q92621 NUP205 Nuclear pore complex protein Nup205 1 S(0.456)VS(0.544)GFLHFDTATK 87.148 0.004104600000000001 3394700.0 43010.0 55006.0 36063.0 34485.0 39913.0 44438.0 43872.0 46301.0 42528.0 23485.0 True False 42396.66951293197 54878.636986558544 33098.03934720571 37021.14193858764 37565.3958119772 42537.4903300375 46143.47749265536 48452.31349011065 37738.048800306366 27544.350958204544 1.5392146860626394 1.9923735748876676 1.201627128460143 1.3440557011041234 1.3638148841836377 1.5443271977830721 1.6752428678632834 1.7590653547666304 1.3700830655828344 1.0 14.749468847883143 -5.259614186518565 24.999847787039126 1.4450412384403364 1.765794112186995 0.2631664741287143 0.2332091067338515 230.34283669156605 3154965.3066028254 0.06074239440175133 0.14461686835484913 5.500292855011538e-06 5.259614186518565 0.3207528737466585 SVS(ph)GSPESDELQELR ddPTM_PC-9_AZD4547_30min_R2 1 SVSGSPESDELQELR 15 0 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 S(0.002)VS(0.821)GS(0.177)PESDELQELR 121.92 5.8181000000000004e-05 3012900.0 6735.0 6805.0 5939.0 9868.6 7844.7 6941.3 4899.4 8847.5 5711.9 7862.8 True False 8876.589903297398 9004.583170972059 5860.244979526335 7593.54673835012 6755.5988143786235 6507.259413698633 5335.4371086045585 7480.322170324191 6013.819372925037 7587.525765250057 1.169892554955279 1.1867614621108704 0.7723525640420943 1.0007935357699396 0.8903559636421193 0.8576260055024904 0.7031853694705341 0.9858710733587429 0.7925929425462509 1.0 12.88941379505319 -5.250578482351736 24.95961037100093 0.8730772972559867 1.1783270640262014 0.6165776978740023 0.0955559018453963 430.90825396429597 990272.632687523 0.023392171182288438 0.06058701040064376 5.615927824655905e-06 5.250578482351736 0.30524976677021465 SVS(ph)LRAR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSLRAR 7 1 Q8TEP8;H0Y966;C9JT09;K7EPA2;A0A0A0MR42;K7ENP4;Q8TEP8-2;Q8TEP8-1 Q8TEP8 CEP192 Centrosomal protein of 192 kDa 1 S(0.068)VS(0.932)LRAR 58.433 0.04384 0.0 7085.6 5660.2 7048.8 6244.1 8683.1 5653.8 6864.2 5764.3 8380.4 6021.0 True False 6984.558044660098 5647.0941546616505 6469.274873154857 6703.311943706984 8172.377129631422 5412.000153651521 7219.59468921145 6032.130421611732 7436.511102475728 7061.7218275218 0.9890729506561742 0.7996766642170907 0.916104461654382 0.9492461056143591 1.1572782572348066 0.7663853498957176 1.0223561428141177 0.8542010813995222 1.0530733557775178 1.0 12.785804276821766 -1.5228787534857435 0.13140990421316417 1.0093505311357511 0.645895017063552 0.04516147923312841 0.11119160232027847 301.93111595913473 2.689282299279869 0.5699271570279654 20.360864778200934 0.029999999433190642 1.5228787534857435 -0.3634555140721991 SVS(ph)LTGAPESVQK ddPTM_PC-9_AZD4547_30min_R2 1 SVSLTGAPESVQK 13 0 A0A087WTP3;Q92945;M0R0I5;M0QXW7;M0QYH3 A0A087WTP3 KHSRP Far upstream element-binding protein 2 1 S(0.003)VS(0.997)LT(0.001)GAPESVQK 103.76 0.0040598 0.0 11728.0 9641.6 10704.0 17022.0 16428.0 13754.0 12422.0 15529.0 11618.0 14087.0 True False 15457.260042445701 12758.058648235732 10562.057966130644 13097.840887278404 14147.255767921284 12893.960205726735 13527.53393539736 13129.349870919961 12232.103761382916 13593.818417749097 1.1370800732679758 0.9385191309880868 0.7769750662801291 0.9635144802417613 1.040712427749482 0.9485164366247106 0.9951239246902701 0.9658323708206451 0.8998283915144677 1.0 13.730663136507065 -4.760042207630628 24.959440971402888 0.9461794080211096 1.137080310097479 0.41356036219176784 0.06764475431843252 37.195434088831355 664223.1998694843 0.017839374389286577 0.10858463932163473 1.7376319458958965e-05 4.760042207630628 0.19090090207636934 SVS(ph)MLSLNTPNSNR ddPTM_PC-9_AZD4547_30min_R2 2 SVSMLSLNTPNSNR 14 0 Q9H8V3-2;Q9H8V3-4;Q9H8V3;Q9H8V3-3;H7C3G1 Q9H8V3-2 ECT2 Protein ECT2 1 S(0.012)VS(0.986)MLS(0.001)LNTPNSNR;S(0.002)VS(0.993)MLS(0.004)LNT(0.001)PNSNR 88.10799999999999 0.0051481 8123700.0 23189.0 28369.0 44019.0 64864.0 51817.0 49125.0 43044.0 48903.0 43705.0 46998.0 True False 30562.61963883644 37538.72446396861 43435.27929849634 49910.606938810124 44623.10397652646 46053.20598417372 46874.83261272293 41346.165029145384 46015.15707447413 45352.61432507788 0.6738888175171137 0.8277080609928907 0.9577238257349733 1.1005012099426403 0.9839147012932387 1.015447657638304 1.0335640692449197 0.9116600144103024 1.0146087002757391 1.0 15.46889809601692 -5.021412909321628 1.9778113546007945 1.0061172250342978 0.6522908515435061 0.8477305050095084 0.04524292597558456 0.1732674050840878 1.0430576957640365 0.012871554334909446 0.09411794487883758 9.518907151396364e-06 5.021412909321628 -0.3538263734907917 SVS(ph)MLSLNTPNSNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVSMLSLNTPNSNR 14 0 Q9H8V3-2;Q9H8V3-4;Q9H8V3;Q9H8V3-3;H7C3G1 Q9H8V3-2 ECT2 Protein ECT2 1 S(0.005)VS(0.992)MLS(0.002)LNT(0.001)PNSNR;S(0.002)VS(0.994)MLS(0.001)LNT(0.002)PNSNR 88.76799999999999 0.0049199 9541100.0 34897.0 46509.0 50053.0 55728.0 67235.0 53965.0 60189.0 50124.0 54918.0 47272.0 True False 40804.37285283241 51126.10615272701 51246.453347059585 52605.74083261369 54060.784400485965 51134.98040004692 54487.46218937608 48808.298110767966 55721.071855351416 55842.039395053915 0.7307106490893412 0.9155486924651142 0.9177038285531998 0.9420454804749328 0.9681018993241547 0.9157076094283206 0.9757426981472704 0.8740421846966258 0.9978337549807822 1.0 15.769064010412986 -4.154625168559287 1.4306141663876395 0.9465803063508627 1.3312267265583868e-17 0.7518464660800026 0.0373483296109562 2.8837094508058976 1.496478198898538 0.009736836060584496 6.08708635608631 7.004462772678351e-05 4.154625168559287 -0.9465803063508627 SVS(ph)MLSLNTPNSNR ddPTM_PC-9_Lapatinib_30min_R1 2 SVSMLSLNTPNSNR 14 0 Q9H8V3-2;Q9H8V3-4;Q9H8V3;Q9H8V3-3;H7C3G1 Q9H8V3-2 ECT2 Protein ECT2 1 SVS(1)MLSLNTPNSNR;SVS(0.988)MLS(0.005)LNT(0.007)PNSNR 130.72 1.6379e-05 7939400.0 53742.0 45024.0 54837.0 38689.0 46435.0 43078.0 41095.0 36866.0 53342.0 32558.0 True False 52975.62922492424 44919.74969426634 50328.51353694141 41534.31812272055 43703.78459472255 41235.65435972267 43222.69802062071 38578.92894594977 47334.06224383803 38185.606919191974 1.387319293812215 1.176352906720197 1.3179969521879316 1.0876956391086068 1.1445093615300679 1.0798742690403005 1.1319107252135125 1.0103002690932774 1.2395786282513706 1.0 15.220741333538315 -1.5228787452804122 0.3643136565808941 1.0754526755743867 4.772189530665552 0.5366531739227333 0.0816450508453426 48.87193743427308 0.6792912132083423 0.06152165362058395 125.78038265807439 0.029999999999994843 1.5228787452804122 3.6967368550911655 SVS(ph)NGALR ddPTM_PC-9_AZD4547_30min_R2 1 SVSNGALR 8 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 S(0.12)VS(0.88)NGALR 77.288 0.023754 23435000.0 41528.0 50978.0 67325.0 98517.0 61359.0 71680.0 55140.0 87127.0 58397.0 56642.0 True False 54733.040163939775 67455.6415708763 66432.22651062644 75805.42772247727 52840.361983435716 67197.8382686123 60047.35317966597 73663.52412928354 61483.746200161615 54658.98082048299 1.0013549345843096 1.2341181734145665 1.2153945337694902 1.3868796414526234 0.9667279043672589 1.2294015962227836 1.098581647119987 1.3476929687221457 1.1248608239164442 1.0 15.738170938954235 -6.2576050029803 24.975555028422807 1.1488735567802035 1.2116253050797952 0.06883982528175558 0.13412980529058194 1206.9659028775827 7861665.154201682 0.0396900730631563 0.04916097938488294 5.525797899914564e-07 6.2576050029803 0.06275174829959163 SVS(ph)NGALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVSNGALR 8 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 S(0.121)VS(0.879)NGALR 68.786 0.042647000000000004 19468000.0 37673.0 36315.0 62286.0 48587.0 52437.0 59439.0 58135.0 42531.0 51144.0 34073.0 True False 44050.29482433321 39920.113202526 63771.134460970396 45864.82791117931 42162.34627215409 56321.914203620654 52628.03193904832 41414.60631531944 51891.88424505796 40250.16517828041 1.0944127714562375 0.9917999845642246 1.5843695095040815 1.1394941538259489 1.0475074098554389 1.3992964737946665 1.3075233780021154 1.0289300958612557 1.2892340693563065 1.0 15.296707083308307 -11.01602907756065 2.7814441675319226 0.9918673886510232 1.2101948399150375 0.1105004800358157 0.17801984606303634 37639926.46424738 40095589.27733524 2354530.3735701405 0.043649389463800994 9.637644940020968e-12 11.01602907756065 0.21832745126401432 SVS(ph)NGALR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSNGALR 8 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 S(0.12)VS(0.88)NGALR 77.288 0.023754 17417000.0 47217.0 57516.0 68160.0 53314.0 67981.0 62116.0 69789.0 56102.0 80980.0 49797.0 True False 46543.6769214627 57382.825235772536 62556.147905208694 57234.889410290336 63982.4912357883 59459.443479468275 73402.33293980036 58708.70373042028 71859.17964279553 58404.34509966836 0.796921476339386 0.9825095228419636 1.0710872247339678 0.9799765636035757 1.0955090948558828 1.0180654089691334 1.2567957540579828 1.0052112326614147 1.2303738620845106 1.0 15.83378808462313 -3.8232322467350426 0.664534322626686 1.1038316972973006 4.6256273034308936e-12 0.5006464170328327 0.08838599584483631 8.121164288054503 1.0487543569031688 0.03524741698996379 9.084312583256068 0.0001502338348955963 3.8232322467350426 -1.103831697292675 SVS(ph)PAVHR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSPAVHR 8 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 S(0.118)VS(0.882)PAVHR 66.962 0.033195999999999996 0.0 49273.0 42349.0 63030.0 48081.0 46172.0 50522.0 49668.0 45349.0 52769.0 33853.0 True False 48570.35798443846 42250.94349241483 57847.916702835995 51617.037133514124 43456.25373764465 48361.291832534225 52239.56601260955 47456.08009466381 46825.59953779549 39704.445943712926 1.2232977146512587 1.06413633254855 1.456963202177514 1.3000316691659444 1.0944933924843196 1.2180321544114654 1.3157107414788525 1.1952334043885162 1.1793540603532884 1.0 15.277012943134773 -8.783179735436187 1.5561689178701703 1.0003943906097716 1.2361421350376136 0.30954191751027094 0.10514227363805435 1.2267824653685735 5.069048731569776 0.1034507191315667 0.02984920769667495 1.6474804305331773e-09 8.783179735436187 0.23574774442784197 SVS(ph)PCSNVESR ddPTM_PC-9_AZD4547_30min_R2 1 SVSPCSNVESR 11 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.028)VS(0.971)PCSNVESR 164.22 0.0016412 19020000.0 43388.0 34386.0 48972.0 51326.0 44932.0 47357.0 37781.0 46747.0 40969.0 40222.0 True False 57184.48147353638 45500.60204512052 48322.59928226363 39493.58367879517 38693.96738277567 44395.75930366441 41143.43580850492 39523.32528919412 43134.53770012883 38813.84002262398 1.4733013131451163 1.1722777756233067 1.2449837288476775 1.0175129195095094 0.9969116006100288 1.1438126008090623 1.0600197193713132 1.0182791825327406 1.111318480083042 1.0 15.244283551851893 -1.522878745280454 0.7050193613782569 1.052266331876114 54.655708935274504 0.7865476628066458 0.06495617659957333 129.02230718262084 0.6711842549277347 0.02512464607066924 10911.212860169333 0.02999999999999196 1.522878745280454 53.60344260339839 SVS(ph)PCSNVESR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSPCSNVESR 11 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 S(0.36)VS(0.514)PCS(0.126)NVESR 110.51 0.0019275 14034000.0 68403.0 83692.0 79847.0 74029.0 106480.0 63863.0 52838.0 66941.0 91645.0 64821.0 True False 67427.56067642606 83498.216316021 73282.2878783334 79473.33961350446 100217.0557477346 61131.72836192419 55573.693101680394 70051.32324013508 81322.97503536685 76025.2234814467 0.8869103909031083 1.0982962297558787 0.9639207163424823 1.0453548963640895 1.3182079730708285 0.8040979764675452 0.7309901971579561 0.9214221285022662 1.069684129967905 1.0 16.214190531714447 SVS(ph)PER ddPTM_PC-9_AZD4547_30min_R2 1 SVSPER 6 0 Q14966-3;Q14966;Q14966-2;Q14966-6;Q14966-4;A0A096LNR2;A0A096LNX0;A0A096LPI0;A0A096LNQ0;A0A096LPB4 Q14966-3 ZNF638 Zinc finger protein 638 1 S(0.013)VS(0.987)PER 87.696 0.039516 30085000.0 66971.0 50980.0 43363.0 56760.0 43370.0 53798.0 49639.0 50559.0 63804.0 99467.0 True False 88266.38491666384 67458.28803176423 42787.978287119106 43674.85893325827 37348.8241206931 50434.00255545195 54056.77483651502 42746.268280239674 67176.5491815524 95984.69060539833 0.9195881589027032 0.7028025782683542 0.44577919684113293 0.4550190104045814 0.3891123041093862 0.5254379863846274 0.563181216666596 0.44534464830410736 0.6998673304862879 1.0 16.55051669633137 -8.583385318369752 4.838657501625014 0.9999248273648855 0.5480692190350384 0.4564111061059436 0.14757737349472033 0.3198812695242609 22.049591870741786 0.1520018149807652 0.03956701323697696 2.6098447986408724e-09 8.583385318369752 -0.45185560832984717 SVS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 1 SVSPER 6 0 Q14966-3;Q14966;Q14966-2;Q14966-6;Q14966-4;A0A096LNR2;A0A096LNX0;A0A096LPI0;A0A096LNQ0;A0A096LPB4 Q14966-3 ZNF638 Zinc finger protein 638 1 S(0.009)VS(0.991)PER 95.741 0.034543 27794000.0 36944.0 43451.0 32324.0 36966.0 63303.0 27836.0 80896.0 58532.0 48757.0 39722.0 True False 36417.17178530016 43350.39187912149 29666.445494248317 39684.60295496103 59579.641998486484 26645.5191688853 85084.3990528321 61251.610401571445 43265.47322602847 46587.894773762 0.7816874310837089 0.9305076370082331 0.6367844187489723 0.851822198613515 1.2788652994048006 0.5719408292278509 1.8263198941702574 1.314753772391277 0.928684874818497 1.0 15.507667518579735 -6.605117389330312 1.2462414709978944 1.2375137686994855 0.7993380371821824 0.21478794549778457 0.3136495676919566 0.6485969496108618 2.1158527296156224 0.14454797835965738 0.1508213523859354 2.482462007796447e-07 6.605117389330312 -0.43817573151730305 SVS(ph)PLLSTHVLGK ddPTM_PC-9_AZD4547_30min_R2 1 SVSPLLSTHVLGK 13 0 Q96H12;X6RL08;X6R907;Q96H12-2 Q96H12 MSANTD3 Myb/SANT-like DNA-binding domain-containing protein 3 1 S(0.104)VS(0.894)PLLS(0.001)THVLGK 75.998 0.010048999999999999 28842000.0 125240.0 112560.0 393550.0 697970.0 478940.0 409120.0 250090.0 525570.0 287010.0 368130.0 True False 165063.7148461716 148942.81876923068 388331.2698589984 537063.8000290039 412447.44810617366 383537.6617250922 272347.52551147423 444355.23289712274 302180.762657472 355241.8807500521 0.46465161849064274 0.4192715635182292 1.0931460813096752 1.5118256859102757 1.1610327229304682 1.0796521539501391 0.7666537654187732 1.2508526076906195 0.8506338329800875 1.0 18.43844215068743 -5.263322315455004 23.37754010150186 1.1039788822745649 0.44196146030050626 0.6365792677305675 0.19536847911253757 38.85889862926651 482474.79968572565 0.052830600302969 0.11993350476611125 5.453529723772056e-06 5.263322315455004 -0.6620174219740587 SVS(ph)PLLSTHVLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVSPLLSTHVLGK 13 0 Q96H12;X6RL08;X6R907;Q96H12-2 Q96H12 MSANTD3 Myb/SANT-like DNA-binding domain-containing protein 3 1 S(0.225)VS(0.775)PLLSTHVLGK;S(0.22)VS(0.78)PLLSTHVLGK 120.54 0.00011957 31929000.0 149587.0 195571.0 486370.0 511010.0 604030.0 562090.0 448240.0 445860.0 492030.0 356760.0 True False 174909.12462207803 214985.99639628828 497966.9053684954 482379.7664167728 485674.65756563557 532613.0108971068 405779.4622234288 434156.6474277186 499225.00792069105 421437.76388939406 0.4150295479167898 0.5101251354700884 1.181590612034441 1.1446049873769093 1.1524232026181223 1.26379991669871 0.9628455183478177 1.0301797433171238 1.1845758750079933 1.0 18.68496007035496 -5.231837732405989 6.209856011503659 1.118701244719385 0.4532590980215608 0.8933580075620868 0.09019462017499584 0.05395600318904248 7.054402855297655 0.02374848834667159 0.06187182872105478 5.8635720713218396e-06 5.231837732405989 -0.6654421466978242 SVS(ph)PLLSTHVLGK ddPTM_PC-9_Lapatinib_30min_R1 1 SVSPLLSTHVLGK 13 0 Q96H12;X6RL08;X6R907;Q96H12-2 Q96H12 MSANTD3 Myb/SANT-like DNA-binding domain-containing protein 3 1 S(0.224)VS(0.776)PLLSTHVLGK 106.6 0.0006235 11526000.0 130150.0 102930.0 263670.0 97889.0 160620.0 208990.0 121340.0 135320.0 278660.0 103240.0 True False 128294.03713341303 102691.6719090006 241992.07039563343 105088.08360813117 151172.64739106997 200051.98487948472 127622.39147882025 141607.46120994724 247274.37638011118 121084.89644134686 1.0595379019509528 0.8480964589893679 1.9985322489238253 0.8678876284048812 1.2484847560182497 1.6521629927345172 1.053991003251509 1.1694890557926971 2.0421570620898213 1.0 16.885659395719323 SVS(ph)PLVWCR ddPTM_PC-9_AZD4547_30min_R2 1 SVSPLVWCR 9 0 Q9P270 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 S(0.001)VS(0.999)PLVWCR 102.06 0.0032981 3423500.0 23219.0 20514.0 24289.0 42245.0 27173.0 28079.0 23819.0 28818.0 23012.0 24344.0 True False 30602.15901479767 27144.74932686565 23966.911989849337 32506.06792874375 23400.497990122047 26323.21569118809 25938.844856482832 24364.84027176066 24228.367340070887 23491.723969736908 1.3026782987157837 1.1555026511393858 1.0202278904998454 1.383724241380476 0.9961166758245422 1.1205314571675895 1.1041694892166456 1.0371669743416252 1.0313575696395443 1.0 14.51986497077636 -1.5228787452803378 0.15493009859434245 0.9645696049741749 2.022650243273511 0.34551488368465966 0.10188873632701025 79.89861266369374 0.8079653454727179 0.3274890659592774 19.135480144680844 0.02999999999999998 1.5228787452803378 1.0580806382993364 SVS(ph)PLVWCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVSPLVWCR 9 0 Q9P270 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 S(0.211)VS(0.789)PLVWCR;S(0.018)VS(0.982)PLVWCR 118.03 0.0018222000000000002 7557100.0 42535.0 42963.0 42576.0 52343.0 49705.0 50313.0 50870.0 43777.0 39230.0 34549.0 True False 49735.335395455964 47228.08270742462 43591.17331037915 49410.39140829563 39965.662060328 47674.49770902552 46051.225333093455 42627.90013556558 39803.66453413156 40812.46021026647 1.2186311518398718 1.157197641703165 1.068084920286518 1.2106692699663897 0.9792514799260875 1.1681358453620712 1.128361904571221 1.0444824917671203 0.9752821645414763 1.0 15.316722059666914 -1.5228787452803392 0.12498361330748792 0.9476186992427397 1.750608777119987 0.4376759512066606 0.06666198828711821 89.37482748454845 0.7648403950348035 0.40623699607705943 12.56203989335335 0.029999999999999888 1.5228787452803392 0.8029900778772473 SVS(ph)PLVWCR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSPLVWCR 9 0 Q9P270 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 SVS(1)PLVWCR 102.06 0.0032981 3875100.0 23557.0 23392.0 28496.0 18923.0 22190.0 23231.0 20589.0 18399.0 20556.0 16212.0 True False 23221.07286017529 23337.83726120019 26153.168877740984 20314.660545277497 20884.82782721853 22237.464284105994 21654.997677249303 19253.88470885179 18240.766815723717 19014.22259886788 1.2212475550569124 1.2273884530304038 1.3754529664177888 1.0683929063966593 1.0983792641862744 1.1695174056408715 1.1388841991646115 1.012604360169749 0.9593222505352275 1.0 14.214791334784834 -6.876833300564658 0.4726947564578683 0.9703782513853947 1.2781665090777246 0.6121895617819331 0.07478722454540848 0.7981124750137412 0.38112021875702745 0.07571389802340187 0.09707290236285232 1.3279040621305952e-07 6.876833300564658 0.30778825769232987 SVS(ph)PQGNSVDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVSPQGNSVDR 11 0 B0QY04;A0A494BZS1;A0A0G2JR51;A0A217FLJ2;Q15080;Q15080-3 B0QY04 NCF4 Neutrophil cytosol factor 4 1 S(0.285)VS(0.708)PQGNS(0.007)VDR 100.02 0.00432 2254200.0 8181.1 10244.0 11610.0 12553.0 14437.0 11421.0 12335.0 10812.0 12776.0 8299.0 True False 9565.998645909605 11260.956619762532 11886.826431170197 11849.696107375108 11608.173486871654 10822.06265447857 11166.53950233356 10528.196456260928 12962.824830182635 9803.543005152142 0.9757695397350021 1.1486619290438633 1.2125031149374474 1.2087156756641588 1.1840794170812643 1.103893015901614 1.1390310111829072 1.0739175062248365 1.3222591897001084 1.0 13.259087518808975 -4.764009316225376 5.491083331602472 1.1600305368126305 0.9670927891382747 0.2949599238329692 0.08285132562151382 0.1779520045878511 16.992947800100172 0.019509651648578576 0.1304975412252778 1.7218316388877415e-05 4.764009316225376 -0.1929377476743558 SVS(ph)PS(ph)KT(ph)LS(ph)VPDK ddPTM_PC-9_Lapatinib_30min_R1 1 SVSPSKTLSVPDK 13 1 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3 C9JWC4 HJURP Holliday junction recognition protein 4 S(0.621)VS(0.69)PS(0.69)KT(0.999)LS(0.999)VPDK 95.57 0.0035328000000000004 0.0 21949.0 24014.0 19327.0 17764.0 16151.0 13410.0 11440.0 11973.0 13029.0 11022.0 True False 21636.00323504636 23958.39705841575 17738.008664377474 19070.42381896684 15201.029934087735 12836.485560236802 12032.307223650107 12529.309289585428 11561.536818547593 12927.138014108175 1.673688577582576 1.8533411674160583 1.3721528032747001 1.4752239666780165 1.1759006454095193 0.9929874304913865 0.9307788940226766 0.9692253053933073 0.8943616758736374 1.0 13.6581152865705 -6.024243518525563 0.8382387759996833 0.9227460850193914 1.7957533649811366 0.9150592621448819 0.09434054496147858 0.17685767804970434 0.2513112557154582 0.04421617504767661 0.10119822642739365 9.457067339772711e-07 6.024243518525563 0.8730072799617452 SVS(ph)PSPSVLSEGR ddPTM_PC-9_AZD4547_30min_R2 1 SVSPSPSVLSEGR 13 0 C9IYE1;A0A087X1P3;Q86UW7-3;Q86UW7-2;Q86UW7 C9IYE1 CADPS2 Calcium-dependent secretion activator 2 1 S(0.096)VS(0.877)PS(0.027)PSVLSEGR 132.06 6.0743000000000004e-05 3725600.0 8587.8 9719.4 8952.4 14506.0 13124.0 10334.0 10606.0 14518.0 12639.0 9606.4 True False 11318.541762663304 12861.005976773808 8833.68532660575 11161.865815465895 11301.95913672991 9687.813346370516 11549.913453455516 12274.576690451151 13307.071736970109 9270.08285996059 1.2209752527186604 1.3873668845316538 0.9529240957230564 1.2040740071133893 1.2191864201716487 1.0450622171042494 1.245934219567981 1.324106469799487 1.4354857381530115 1.0 13.178366518995091 -7.5113992905047455 23.9199861631297 1.2848817662829144 1.1726381000144854 0.05259615933839945 0.14883799839036604 735.8166482396932 1533252.1507575696 0.06411122268421499 0.04041715905972637 3.080354568831152e-08 7.5113992905047455 -0.11224366626842897 SVS(ph)PSPVPLLFQPDQNAPPIR ddPTM_PC-9_AZD4547_30min_R2 4 SVSPSPVPLLFQPDQNAPPIR 21 0 Q02241-2;Q02241-3 Q02241-2 KIF23 Kinesin-like protein KIF23 1 S(0.02)VS(0.744)PS(0.237)PVPLLFQPDQNAPPIR;S(0.041)VS(0.889)PS(0.07)PVPLLFQPDQNAPPIR;S(0.022)VS(0.963)PS(0.015)PVPLLFQPDQNAPPIR;S(0.032)VS(0.84)PS(0.128)PVPLLFQPDQNAPPIR 169.62 1.1847e-08 309450000.0 64658.0 60427.4 86106.9 113095.0 86134.0 81388.9 78429.5 92792.3 69242.7 89671.0 True False 85217.89903005246 79959.37532778796 84965.066244751 87022.69505033197 74175.7808810649 76299.63921680047 85409.5735619261 78453.38218992623 72902.72776022616 86531.64558372811 0.984817732925182 0.924047783771998 0.9818958794969259 1.0056747963509918 0.8572098725349252 0.8817541686870252 0.9870328130912951 0.906643825628101 0.842497877723652 1.0 16.400940218396336 -6.250697572189369 24.92960454093537 0.9100423227566684 0.9710894437390312 0.2585076455379941 0.05089157237720534 1033.6961950225807 2399003.260058057 0.015157140480390342 0.01936310460893296 5.614388067022022e-07 6.250697572189369 0.06104712098236276 SVS(ph)PSPVPLLFQPDQNAPPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SVSPSPVPLLFQPDQNAPPIR 21 0 Q02241-2;Q02241-3 Q02241-2 KIF23 Kinesin-like protein KIF23 1 S(0.01)VS(0.532)PS(0.457)PVPLLFQPDQNAPPIR;S(0.031)VS(0.873)PS(0.096)PVPLLFQPDQNAPPIR;S(0.02)VS(0.557)PS(0.424)PVPLLFQPDQNAPPIR;S(0.16)VS(0.828)PS(0.011)PVPLLFQPDQNAPPIR;S(0.084)VS(0.91)PS(0.006)PVPLLFQPDQNAPPIR 178.23 1.0436e-12 230391400.0 50017.0 45019.8 61032.3 65187.8 73696.5 64123.3 65732.6 70791.9 53445.9 46041.9 True False 58483.89021921997 49489.06821850693 62487.541498286686 61535.53890769908 59256.19985975185 60760.561265381824 59505.93226518771 68933.687635218 54227.44517779103 54388.932002520174 1.0752902854667206 0.9099106453536134 1.1489017930227285 1.1313981841902643 1.089490042882367 1.1171493726438022 1.0940816462884477 1.26742123989535 0.9970308881093369 1.0 15.73102547643568 -5.276267981265887 24.91173125747748 1.115570001896349 0.9926004569472455 0.2279574267864516 0.08163817386028081 822.4376463403252 1381676.8931198765 0.019880941906453998 0.04165554711041915 5.293367160534541e-06 5.276267981265887 -0.1229695449491035 SVS(ph)PSPVPLLFQPDQNAPPIR ddPTM_PC-9_Lapatinib_30min_R1 4 SVSPSPVPLLFQPDQNAPPIR 21 0 Q02241-2;Q02241-3 Q02241-2 KIF23 Kinesin-like protein KIF23 1 S(0.019)VS(0.826)PS(0.155)PVPLLFQPDQNAPPIR;S(0.119)VS(0.565)PS(0.316)PVPLLFQPDQNAPPIR;S(0.03)VS(0.61)PS(0.359)PVPLLFQPDQNAPPIR;S(0.027)VS(0.751)PS(0.222)PVPLLFQPDQNAPPIR 156.0 2.7287000000000002e-06 170422100.0 111695.0 109555.5 117401.0 98147.6 110308.2 113110.7 106917.0 100938.8 115228.0 94724.79999999999 True False 110102.20881764578 109301.83097081982 107748.74296096561 105365.70191479582 103820.08855026537 108273.21903492002 112452.63911110134 105628.78514320604 102249.8092353674 111097.85546713797 0.9910381109940803 0.9838338508986846 0.9698543910493124 0.948404462640256 0.9344922826253355 0.9745752389158092 1.0121945076101322 0.950772494203998 0.9203580825699398 1.0 16.761471442947922 -5.286635354895593 3.0042879352943883 0.9621541970319942 0.9889833845253733 0.11798436297055637 0.026355916425167616 0.5783539726936826 10.426530814130192 0.007481213381182958 0.021171214306653776 5.168501481602382e-06 5.286635354895593 0.026829187493379036 SVS(ph)PSPVPLSSNYIAQISNGQQLMSQPQLHR ddPTM_PC-9_AZD4547_30min_R2 1 SVSPSPVPLSSNYIAQISNGQQLMSQPQLHR 31 0 Q02241;H7BYN4 Q02241 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 S(0.169)VS(0.642)PS(0.169)PVPLS(0.006)S(0.006)NY(0.007)IAQIS(0.001)NGQQLMSQPQLHR 48.693999999999996 0.0092118 11098000.0 12215.0 15724.0 26882.0 37730.0 32811.0 24719.0 17992.0 30277.0 20150.0 25850.0 True False 16099.115912216432 20806.475500420947 26525.527115613237 29031.9314226891 28255.759009086003 23173.317022346884 19593.25314487758 25598.385346245333 21215.087862959703 24944.999368127636 0.6453844986978177 0.834094048004086 1.0633605046109984 1.1638377293279614 1.1327223782249738 0.9289764525693097 0.7854581535853631 1.026193064528698 0.850474580090242 1.0 14.606463012351425 -4.952034012459021 3.1429480430437553 0.9952701472936886 0.6444759310413601 0.4922421206961951 0.11117782707202765 0.25362168896395587 4.670719045128648 0.031955987308030585 0.18032798041172257 1.116775782294463e-05 4.952034012459021 -0.35079421625232843 SVS(ph)PSPVPLSSNYIAQISNGQQLMSQPQLHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVSPSPVPLSSNYIAQISNGQQLMSQPQLHR 31 0 Q02241;H7BYN4 Q02241 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 S(0.237)VS(0.543)PS(0.176)PVPLS(0.01)S(0.015)NY(0.017)IAQIS(0.002)NGQQLMS(0.001)QPQLHR 51.452 0.005263 10470000.0 11421.0 12150.0 15897.0 20596.0 21107.0 16289.0 19985.0 16381.0 13943.0 11395.0 True False 13354.349724967733 13356.171703447362 16276.04476970823 19442.07289313294 16971.234867867293 15434.776164854346 18091.8761211298 15951.016107104178 14146.889997435535 13460.82329722964 0.9920901144075029 0.9922254685711672 1.2091418489282146 1.4443450050439557 1.2607872856751734 1.1466442894344333 1.3440393445216143 1.184995579756778 1.0509676626055329 1.0 13.716479030991458 -5.2714814840012085 6.167335866424845 1.225642129476814 0.9906057438289048 0.3125564721477986 0.12349887721634374 0.15244217656906647 27.39987421065496 0.032405785711276384 0.07503858621278536 5.352029714830888e-06 5.2714814840012085 -0.2350363856479093 SVS(ph)PTFLNPSDENLK ddPTM_PC-9_AZD4547_30min_R2 4 SVSPTFLNPSDENLK 15 0 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 S(0.011)VS(0.972)PT(0.016)FLNPSDENLK;S(0.039)VS(0.952)PT(0.009)FLNPSDENLK;S(0.001)VS(0.998)PT(0.002)FLNPSDENLK;S(0.048)VS(0.952)PTFLNPSDENLK 257.54 4.496e-50 395959000.0 298642.0 275637.0 372701.0 480516.0 439654.0 392078.0 366476.0 410439.0 330710.0 388223.0 True False 393603.94386051176 364731.269874684 367758.74122149247 369740.4600981943 378615.63108045235 367561.30067914247 399091.6540419158 347015.08349993743 348190.6554421541 374631.4309358852 1.050643142453986 0.9735735972914256 0.9816547968299838 0.9869445795685843 1.0106349863240627 0.9811277707290057 1.0652914333560464 0.9262839549608585 0.9294218976029905 1.0 18.515112418740365 -7.794530141790908 24.99990251757987 0.9458896668599753 1.003213400862588 0.34330576446317107 0.03440581415729063 208.23692577224259 157319.2567821103 0.018077913475152824 0.008685281526014997 1.6049808620778526e-08 7.794530141790908 0.05732373400261259 SVS(ph)PTFLNPSDENLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SVSPTFLNPSDENLK 15 0 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 S(0.003)VS(0.566)PT(0.431)FLNPSDENLK;S(0.001)VS(0.998)PT(0.001)FLNPSDENLK;S(0.018)VS(0.749)PT(0.214)FLNPS(0.02)DENLK;SVS(0.995)PT(0.005)FLNPSDENLK;S(0.019)VS(0.568)PT(0.402)FLNPS(0.011)DENLK 213.83 1.3018e-17 172076900.0 83447.7 65580.3 81680.0 91044.0 97937.0 83703.0 88139.0 83482.0 73314.4 60034.6 True False 97573.74744279764 72090.67877889634 83627.56097312497 85943.09984863031 78746.94789663702 79313.4673292899 79789.83584889953 81290.68595649031 74386.48440278186 70918.39774636792 1.3758594461166442 1.0165299988406529 1.1792082679618625 1.2118590179659252 1.1103881418509634 1.1183764699950787 1.1250936059534138 1.1462566631470972 1.0489024959195663 1.0 16.11387232146172 -1.5228787564268942 0.056943521285872496 0.784976909581853 1.8313751784744317 0.3741048106119511 0.08169180284982118 454.53790984798275 1.9476027199033268 7.603498470078197 40.07503332470621 0.029999999230023156 1.5228787564268942 1.0463982688925788 SVS(ph)PTFLNPSDENLK ddPTM_PC-9_Lapatinib_30min_R1 4 SVSPTFLNPSDENLK 15 0 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 S(0.001)VS(0.999)PTFLNPSDENLK;S(0.001)VS(0.999)PTFLNPSDENLK;S(0.019)VS(0.978)PT(0.002)FLNPSDENLK;S(0.027)VS(0.961)PT(0.008)FLNPS(0.004)DENLK 265.56 1.4493999999999999e-61 343808000.0 381493.0 283293.0 310174.0 302517.0 338707.0 288216.0 269419.0 263602.0 313771.0 220837.0 True False 376052.8398627512 282637.0524639694 284672.69102626503 324765.10934712813 318784.92018358316 275889.67354431114 283368.19754270866 275849.91124641226 278430.80582489 259008.3812031942 1.4518944835523862 1.0912274388612866 1.0990867928823391 1.253878765769928 1.230789979469791 1.0651766258014386 1.0940503014858194 1.0650231083835304 1.0749876298653778 1.0 17.982639256999796 -1.5228787452803376 0.21620838074398052 1.018659375628002 2.513725336344169 0.5044327350509781 0.08894286334011264 50.63518842938448 0.6410695371251268 0.14954857920619163 26.267675144137826 0.029999999999999995 1.5228787452803376 1.495065960716167 SVS(ph)PTTEMVSNESVDYR ddPTM_PC-9_AZD4547_30min_R2 3 SVSPTTEMVSNESVDYR 17 0 P08581;P08581-2 P08581 MET Hepatocyte growth factor receptor 1 S(0.003)VS(0.959)PT(0.035)T(0.003)EMVS(0.001)NESVDYR;S(0.097)VS(0.753)PT(0.115)T(0.031)EMVSNESVDY(0.003)R;S(0.001)VS(0.725)PT(0.238)T(0.036)EMVSNESVDYR 123.14 4.8746000000000004e-05 15488800.0 33952.7 45054.3 48834.799999999996 49703.1 41343.3 28202.0 36250.3 50618.9 32198.0 32360.4 True False 44748.95233996813 59617.22139014344 48187.2186439085 38244.81820024009 35603.496432304586 26438.524481743876 39476.50647386374 42796.912111604746 33899.92054648019 31227.472245739176 1.4329995072231274 1.9091273517432361 1.5431034015403982 1.2247170664112397 1.140133794760237 0.8466431183955747 1.2641595247674937 1.3704891569455853 1.0855800392587223 1.0 14.930528172534908 -5.736486929286804 3.0109565606819158 1.1340543540526982 1.6827242682881804 0.6447439021635171 0.1710377703989446 0.15477744082979672 2.869850619993627 0.05004480698041294 0.08936163738268167 1.8344803775960012e-06 5.736486929286804 0.5486699142354823 SVS(ph)PTTEMVSNESVDYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SVSPTTEMVSNESVDYR 17 0 P08581;P08581-2 P08581 MET Hepatocyte growth factor receptor 1 S(0.002)VS(0.672)PT(0.303)T(0.017)EMVS(0.005)NESVDYR;S(0.002)VS(0.566)PT(0.426)T(0.006)EMVSNESVDYR;S(0.002)VS(0.925)PT(0.037)T(0.037)EMVSNESVDYR;S(0.104)VS(0.842)PT(0.034)T(0.015)EMVS(0.005)NESVDYR 122.16 5.4659e-05 30085800.0 120022.0 111884.0 108838.0 85617.0 137943.0 78782.0 68700.0 77837.0 75689.0 62153.5 True False 140339.35405744478 122991.1041044036 111433.11069041365 80820.15706405896 110914.05938211126 74650.53323221536 62192.2386550721 75793.86122511866 76795.80843548012 73421.4375431648 1.9114220417563828 1.6751388725138563 1.517718998962689 1.1007705619567096 1.51064951999754 1.016740283630758 0.8470583079840817 1.0323124112158537 1.0459589325029426 1.0 16.163913741277725 -4.802811319413938 0.4688091137850596 0.9552010518496303 2.599459773612376 0.8201296440978358 0.14356694350577517 1.9582990324586087 0.33855791703858434 0.10217914535507926 1.7958557331463723 1.574666834774348e-05 4.802811319413938 1.6442587217627456 SVS(ph)PTTEMVSNESVDYR ddPTM_PC-9_Lapatinib_30min_R1 2 SVSPTTEMVSNESVDYR 17 0 P08581;P08581-2 P08581 MET Hepatocyte growth factor receptor 1 S(0.146)VS(0.83)PT(0.024)TEMVSNESVDYR;S(0.001)VS(0.962)PT(0.018)T(0.018)EMVSNESVDYR 222.09 2.613e-23 9199000.0 36393.0 39670.0 20462.8 12610.6 20707.2 12676.8 9911.6 10290.6 19605.2 7750.4 True False 35874.02914634117 39578.14655231753 18780.427572692264 13538.025591728387 19489.243207921572 12134.642815064122 10424.77415016874 10768.738843682268 17397.055924091575 9090.046313241148 3.9465177525096595 4.354009340377666 2.066043111940528 1.4893241602089557 2.144020232276736 1.3349374026167522 1.146833997422361 1.1846737049068528 1.9138577873635145 1.0 13.150071929544959 -5.357310880396865 3.4663496499749487 1.4895294466497724 4.179200416855998 0.9003324153913304 0.3519033261810156 0.06656080941204677 1.4864840685715217 0.09757646552176096 0.23395321713748155 4.392270915788902e-06 5.357310880396865 2.689670970206226 SVS(ph)SENPTYPSAPLKPVTVPPR ddPTM_PC-9_AZD4547_30min_R2 2 SVSSENPTYPSAPLKPVTVPPR 22 1 A0A0U1RQE4;A0A494C1M0;Q5HYK7-2;Q5HYK7;A0A0U1RQN2;Q5HYK7-3 A0A0U1RQE4 SH3D19 SH3 domain-containing protein 19 1 S(0.353)VS(0.602)S(0.044)ENPT(0.001)YPSAPLKPVTVPPR;S(0.033)VS(0.748)S(0.209)ENPT(0.006)Y(0.003)PSAPLKPVTVPPR 98.92399999999999 5.4385e-05 13918400.0 20009.6 22181.3 24961.3 38306.0 36383.0 25874.5 22422.4 35375.0 26520.0 26366.9 True False 26372.23657446466 29350.971446037085 24630.29685257631 29475.143521800397 31331.848466294112 24256.563424681994 24417.950162055527 29908.60658663105 27921.79305834694 25443.80285645974 1.036489581500165 1.15356071620345 0.9680273421204844 1.1584409645084626 1.2314137412183062 0.9533387584208417 0.9596816285603404 1.1754770603812383 1.097390716940651 1.0 14.635026692944384 -6.782612727197109 24.999991401739052 1.0433015133255092 1.106879328284703 0.13587040493416425 0.09051951866793176 622.370181934136 734846.2478056622 0.03358568793376011 0.029649664158930195 1.6496327605268231e-07 6.782612727197109 0.06357781495919368 SVS(ph)SENPTYPSAPLKPVTVPPR ddPTM_PC-9_Lapatinib_30min_R1 2 SVSSENPTYPSAPLKPVTVPPR 22 1 A0A0U1RQE4;A0A494C1M0;Q5HYK7-2;Q5HYK7;A0A0U1RQN2;Q5HYK7-3 A0A0U1RQE4 SH3D19 SH3 domain-containing protein 19 1 S(0.152)VS(0.658)S(0.152)ENPT(0.031)Y(0.007)PSAPLKPVTVPPR;S(0.169)VS(0.781)S(0.047)ENPT(0.002)YPSAPLKPVTVPPR 103.71 0.00049917 6702300.0 16857.5 14982.4 17502.9 11324.3 15161.5 12615.5 12858.8 17286.800000000003 18888.4 21551.0 True False 16617.108958713117 14947.709173315914 16063.87912514785 12157.12679875738 14269.730378655875 12075.964473166845 13524.565745408387 18090.007836566074 16760.98948833021 25276.06163509756 0.6574247680912089 0.5913780947803983 0.6355372667252102 0.48097393392475224 0.5645551346037773 0.4777628986470951 0.5350740926596171 0.7156972513252162 0.6631171315493398 1.0 14.625484068454194 -8.810841903594142 0.9885852964279123 0.9981900365190751 0.5643769340327661 0.7875495580328747 0.06619473084755216 0.45602660879590556 0.8256686993029896 0.06642326363024402 0.02158428598618837 1.5458170615720146e-09 8.810841903594142 -0.433813102486309 SVS(ph)SNVASVSPIPAGSK ddPTM_PC-9_AZD4547_30min_R2 4 SVSSNVASVSPIPAGSK 17 0 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 S(0.325)VS(0.518)S(0.155)NVAS(0.002)VSPIPAGSK;S(0.005)VS(0.775)S(0.22)NVASVSPIPAGSK;SVS(0.969)S(0.027)NVAS(0.004)VSPIPAGSK;S(0.003)VS(0.953)S(0.044)NVASVSPIPAGSK 226.14 8.346099999999999e-43 26633400.0 92839.0 96847.0 123741.0 177978.0 119804.0 115925.0 159743.0 276158.0 206851.0 167995.0 True False 122359.8708288383 128150.89880369305 122100.11348906683 136947.92183268908 103171.28256757016 108676.1914242307 173959.8175368042 233484.12657952996 217784.7215653141 162113.5461836981 0.7547788183609707 0.7905008669570373 0.7531765010600023 0.8447654440765071 0.6364137050623898 0.67037082330606 1.0730739141298073 1.4402505655817228 1.3434085348952425 1.0 17.30664512171124 -7.458213827759234 3.884781654905194 1.2920017300607498 0.7464065888113165 0.7957297909825606 0.11948596126330574 0.0923164514823832 2.7351146079496957 0.05401214793067599 0.033680634606205864 3.4816585107030954e-08 7.458213827759234 -0.5455951412494333 SVS(ph)SNVASVSPIPAGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SVSSNVASVSPIPAGSK 17 0 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 S(0.001)VS(0.682)S(0.206)NVAS(0.111)VSPIPAGSK;S(0.006)VS(0.836)S(0.158)NVASVSPIPAGSK;SVS(0.771)S(0.229)NVASVSPIPAGSK 224.99 1.0820999999999998e-66 10707500.0 102900.0 76689.0 62261.0 73509.0 122106.0 98284.0 118232.0 161731.0 114557.0 87016.0 True False 120318.93763235991 84302.17710005541 63745.53836615735 69390.52904939353 98180.20584525546 93129.8140209063 107032.20903444655 157485.73261815897 116232.1794044484 102791.31198172306 1.1705166060508438 0.8201294007711942 0.620145196487926 0.6750621984641232 0.95514109074425 0.9060086132324623 1.0412573491957915 1.5320918624539097 1.1307587884967867 1.0 16.649358806180977 -7.406660735182384 3.006605463814222 1.252810004916239 0.8386076795998605 0.40850859625677005 0.1917868751539976 0.23745602755999404 4.100977084910277 0.09345289221246532 0.057609662580631826 3.920480199832323e-08 7.406660735182384 -0.41420232531637846 SVS(ph)SNVASVSPIPAGSK ddPTM_PC-9_Lapatinib_30min_R1 3 SVSSNVASVSPIPAGSK 17 0 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 S(0.01)VS(0.925)S(0.058)NVAS(0.007)VSPIPAGSK;S(0.024)VS(0.91)S(0.066)NVASVSPIPAGSK;S(0.026)VS(0.963)S(0.011)NVASVSPIPAGSK 251.0 6.5243e-48 18079600.0 80804.0 82221.0 72757.0 54286.0 108626.0 100617.0 140307.0 103028.0 109990.0 132043.0 True False 79651.72014236113 82030.62232614336 66775.20031014187 58278.37353278728 102236.83224693294 96313.84545968274 147571.40993257656 107815.05700220562 97601.76795395273 154866.45661376198 0.514325192711118 0.5296861833077792 0.43117923513081774 0.376313727369213 0.6601612413843257 0.621915471985584 0.9528945980898929 0.6961808215906762 0.6302318144811192 1.0 17.240665171066276 -6.691090318217586 1.8930942787545075 0.7887413199380007 0.4693323769688648 0.6121058877717395 0.12021576137113195 0.24048065715240652 1.774528989987201 0.047547354763371213 0.045806573867210904 2.036618487520596e-07 6.691090318217586 -0.31940894296913586 SVS(ph)SYGNIR ddPTM_PC-9_AZD4547_30min_R2 1 SVSSYGNIR 9 0 Q8N122-3;Q8N122 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 1 S(0.001)VS(0.69)S(0.309)YGNIR 180.09 0.006979600000000001 36824000.0 43373.0 52688.0 77932.0 125560.0 80796.0 62332.0 85896.0 111150.0 64641.0 89717.0 True False 57164.711785555766 69718.3656300037 76898.5707601357 96614.0818826622 69578.87004047754 58434.37018637186 93540.5775973991 93974.32147290591 68057.79129278306 86576.03513772952 0.6602833185259093 0.8052848056519591 0.888220055790284 1.1159448654464674 0.8036735561958684 0.6749485593029471 1.0804442297292782 1.085454205929006 0.786104274520233 1.0 16.401680111514445 -4.960223337461706 2.1171681533591844 0.931382919240406 0.6384736121968645 0.2776249435114445 0.13758987202917833 0.6570099698127816 4.440638203819403 0.03896722688846101 0.3229617834023876 1.095914473342784e-05 4.960223337461706 -0.29290930704354146 SVS(ph)TMNLSK ddPTM_PC-9_AZD4547_30min_R2 4 SVSTMNLSK 9 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40 Q14244-5 MAP7 Ensconsin 1 SVS(0.686)T(0.314)MNLSK;S(0.002)VS(0.989)T(0.009)MNLSK;SVS(0.996)T(0.004)MNLSK;S(0.004)VS(0.498)T(0.498)MNLSK 96.64 0.0050398000000000005 74387000.0 322302.0 346478.0 653974.0 816083.0 580233.0 709616.0 673460.0 616614.0 540354.0 653193.0 True False 424787.33170193783 458470.2377534249 645301.8774609796 627947.672706663 499677.66350062506 665243.5993417908 733396.6353351065 521330.4746801099 568916.0092854449 630324.9118864747 0.6739180439983063 0.7273554148150155 1.0237607070450079 0.9962285495385278 0.7927303111107562 1.0553979174816512 1.163521576737547 0.8270821362903782 0.9025757963186929 1.0 19.26573615691325 -5.1936930113240765 5.406646359838871 0.9683987352879708 0.6916097547130046 0.5223511115808839 0.10327017795604615 0.17733048170474996 9.96351126858563 0.027712825230297083 0.07633664455012824 6.401872031409244e-06 5.1936930113240765 -0.27678898057496626 SVS(ph)TMNLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SVSTMNLSK 9 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40 Q14244-5 MAP7 Ensconsin 1 S(0.001)VS(0.586)T(0.408)MNLS(0.005)K;SVS(0.952)T(0.048)MNLSK;SVS(0.98)T(0.02)MNLSK;SVS(0.584)T(0.413)MNLS(0.003)K 119.03 0.0015517 79537100.0 489539.0 560532.0 682448.0 795351.0 850713.0 821747.0 860321.0 765429.0 814499.0 548299.0 True False 572408.2838640203 616177.9125330661 698720.148518454 750790.0620327317 684021.8945443698 778653.1407170834 778825.1666953467 745337.2997890644 826409.5069942822 647701.2683675041 0.883753532406605 0.9513304089802218 1.078769152760099 1.1591610186669192 1.0560762004811413 1.2021794286116443 1.2024450232409352 1.1507423810789295 1.2759115156238656 1.0 19.304969043693184 -5.003402045750785 0.8904924765047013 1.1676489419492175 0.7682609691511548 0.6113623091448692 0.07351022371019447 1.038329848579194 0.8107163495797081 0.025717116962622293 0.37802000769028005 9.921971020695664e-06 5.003402045750785 -0.3993879727980627 SVS(ph)TMNLSK ddPTM_PC-9_Lapatinib_30min_R1 4 SVSTMNLSK 9 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40 Q14244-5 MAP7 Ensconsin 1 SVS(0.857)T(0.143)MNLSK;S(0.001)VS(0.953)T(0.046)MNLSK;SVS(0.998)T(0.002)MNLSK;S(0.034)VS(0.954)T(0.011)MNLSK 141.1 0.00064935 65100200.0 790170.0 691792.0 775370.0 612153.0 717546.0 761386.0 579282.0 615772.0 673191.0 418097.0 True False 778902.030900568 690190.1981275746 711622.0716147551 657172.7737025453 675341.3550297149 728823.2956574536 609274.3875114047 644383.0151062052 597369.1405644999 490364.50937076646 1.5884143652648346 1.40750438691663 1.4512103914859282 1.3401719764463103 1.3772231516026923 1.4862888356106285 1.242492831084417 1.3140898307120037 1.2182144693363746 1.0 18.903495040725595 -12.471816927779246 0.08023398639464575 1.0765826663778126e-11 1.8436068812133442 0.8208908877394441 0.06583176374180681 63.06174574310029 0.5506723333821563 13.615058125280289 2.6492281357229324 3.3742951850869165e-13 12.471816927779246 1.8436068812025783 SVS(ph)TPPR ddPTM_PC-9_AZD4547_30min_R2 1 SVSTPPR 7 0 Q9UQ84;Q9UQ84-4 Q9UQ84 EXO1 Exonuclease 1 1 S(0.001)VS(0.5)T(0.5)PPR 101.6 0.011146 13641000.0 127720.0 112230.0 167750.0 215470.0 211890.0 166000.0 144660.0 201290.0 152150.0 180680.0 True False 168332.3032589672 148506.1527227325 165525.52539409706 165796.72047831488 182472.7309876337 155619.993758226 157534.45975644665 170185.25568404145 160192.33837961874 174354.44819471176 0.9654603309631695 0.8517485745869073 0.9493622164961635 0.9509176404444813 1.0465619482438198 0.892549604380819 0.9035299149954509 0.976087833985088 0.9187740263484567 1.0 17.411663645586643 SVS(ph)TPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVSTPPR 7 0 Q9UQ84;Q9UQ84-4 Q9UQ84 EXO1 Exonuclease 1 1 S(0.015)VS(0.492)T(0.492)PPR;S(0.021)VS(0.49)T(0.49)PPR 92.47 0.014563999999999999 20801700.0 237230.0 228840.0 288170.0 292120.0 348760.0 322680.0 291730.0 303320.0 285800.0 233870.0 True False 277388.35349392286 251557.72284912653 295041.06569081044 275753.46346581774 280422.9815946082 305758.0927543252 264095.22245770326 295358.1713941059 289979.28431952046 276268.77968609903 1.004052480374713 0.9105542911325355 1.067949357238414 0.9981347287201008 1.015036812748908 1.1067413882297246 0.955935820029221 1.0690971731575913 1.0496274122939244 1.0 18.075713011118737 -5.267026915323641 24.96916718873949 1.0333040712962418 0.9573033854746608 0.3010468545689222 0.04601899085906723 477.40309547983856 2133392.180161686 0.011359650910838102 0.02475587024760486 5.407208108305999e-06 5.267026915323641 -0.07600068582158104 SVS(ph)TTNIAGHFNDESPLGLR ddPTM_PC-9_AZD4547_30min_R2 5 SVSTTNIAGHFNDESPLGLR 20 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF5;V9GYG5;V9GZ14 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 S(0.148)VS(0.556)T(0.148)T(0.148)NIAGHFNDESPLGLR;S(0.008)VS(0.799)T(0.18)T(0.013)NIAGHFNDESPLGLR;S(0.43)VS(0.559)T(0.009)T(0.003)NIAGHFNDESPLGLR;S(0.129)VS(0.836)T(0.018)T(0.018)NIAGHFNDESPLGLR;S(0.156)VS(0.649)T(0.156)T(0.039)NIAGHFNDESPLGLR 133.53 2.7665e-05 136303800.0 43907.5 51488.2 72937.8 101664.8 87229.9 78368.4 54991.8 103804.6 75277.20000000001 70942.8 True False 57869.17166726512 68130.75374337156 71970.59711528812 78227.55106550231 75119.53408267582 73468.01155929003 59885.96366676746 87763.98426240585 79256.19911055031 68459.11416530784 0.8453099689185103 0.995203554326698 1.0512931403333838 1.1426900861820486 1.0972904776606531 1.073166260695212 0.8747697716648971 1.2819912342202187 1.1577158144227635 1.0 16.062955004097233 -4.763565252862641 1.5414406991293714 1.091708142742888 0.7437576875381037 0.35503806100849633 0.09993853175732272 1.3133547113785333 2.8580146119233656 0.02910805498109909 0.709792782971759 1.723593101244056e-05 4.763565252862641 -0.3479504552047844 SVS(ph)TTNIAGHFNDESPLGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SVSTTNIAGHFNDESPLGLR 20 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF5;V9GYG5;V9GZ14 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 S(0.173)VS(0.638)T(0.173)T(0.016)NIAGHFNDESPLGLR;S(0.011)VS(0.927)T(0.049)T(0.013)NIAGHFNDESPLGLR;S(0.181)VS(0.758)T(0.057)T(0.004)NIAGHFNDESPLGLR;S(0.005)VS(0.332)T(0.332)T(0.332)NIAGHFNDESPLGLR;S(0.159)VS(0.554)T(0.222)T(0.065)NIAGHFNDESPLGLR;S(0.165)VS(0.586)T(0.177)T(0.071)NIAGHFNDESPLGLR 290.94 2.2833999999999996e-107 201583500.0 87533.2 83020.1 135481.8 133508.4 163062.7 128274.8 112593.6 100219.0 117962.4 98000.7 True False 102350.8419004945 91261.78686727327 138712.1999295877 126028.35718807265 131111.73449038598 121547.84367312033 101927.91910092781 97588.35744080805 119687.37693706433 115767.45113688578 0.8841072416760113 0.7883199117804147 1.1981968901221776 1.0886337735729723 1.1325440199539059 1.0499310685297865 0.8804540317675836 0.8429688697682183 1.033860344696918 1.0 16.82087016054387 -7.252765694020688 24.521367762551943 0.9262348831611413 1.0287678809315188 0.09854567967422012 0.12177974419945786 1108.6370802966744 3134232.4752663067 0.051135967581593174 0.038954276342037374 5.587715759790225e-08 7.252765694020688 0.1025329977703775 SVS(ph)TTNIAGHFNDESPLGLR ddPTM_PC-9_Lapatinib_30min_R1 4 SVSTTNIAGHFNDESPLGLR 20 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF5;V9GYG5;V9GZ14 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 S(0.17)VS(0.581)T(0.17)T(0.079)NIAGHFNDESPLGLR;S(0.166)VS(0.69)T(0.072)T(0.072)NIAGHFNDESPLGLR;S(0.164)VS(0.627)T(0.164)T(0.044)NIAGHFNDESPLGLR;S(0.041)VS(0.692)T(0.204)T(0.062)NIAGHFNDES(0.001)PLGLR 135.86 5.5693000000000004e-05 122829000.0 76531.0 81207.9 104608.0 69879.0 74629.9 87764.0 68072.4 62829.4 99697.0 57756.9 True False 75439.65390593343 81019.86809694837 96007.53403855753 75018.13476951032 70240.3160100287 84010.53830787641 71596.85579118873 65748.68329400152 88468.07400404788 67740.10320876833 1.1136631084460538 1.1960399270023714 1.4172924086441345 1.1074405147909476 1.036908901563893 1.2401891099717433 1.0569345542703747 0.9706020537254062 1.3059926072358938 1.0 16.04772256447223 -5.944351798898052 24.999881219811083 1.1019968026671387 1.2418137006433179 0.22184142260984263 0.1199820656587156 130.6906722714606 58711.47692652658 0.033190079995468504 0.04922883975539147 1.1367061275101177e-06 5.944351798898052 0.13981689797617913 SVS(ph)VATGLNMMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVSVATGLNMMK 12 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 S(0.001)VS(0.996)VAT(0.003)GLNMMK 87.21600000000001 0.0051997 9229400.0 57417.0 58656.0 53715.0 58675.0 63045.0 51836.0 66551.0 61400.0 51797.0 42300.0 True False 67136.5640625579 64478.98003600072 54995.769315271886 55387.62997691659 50691.78482231928 49117.628907937244 60246.8074924849 59788.315058677515 52554.433134703366 49968.65515338426 1.3435735633963906 1.2903885413380736 1.100605352424562 1.1084474818643448 1.014471665621484 0.9829687982829497 1.205691994462343 1.1965163936301815 1.0517480002890167 1.0 15.608735769733473 -5.21156379395653 2.994008144649382 1.0867892849436362 1.3374881584641283 0.6335603141660029 0.07183089454167257 0.1836016476995284 3.219164656430867 0.020697043097344197 0.06709370166786899 6.143787783559004e-06 5.21156379395653 0.250698873520492 SVS(ph)VATGLNMMK ddPTM_PC-9_Lapatinib_30min_R1 3 SVSVATGLNMMK 12 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 S(0.001)VS(0.915)VAT(0.084)GLNMMK;S(0.024)VS(0.968)VAT(0.008)GLNMMK;S(0.082)VS(0.912)VAT(0.006)GLNMMK 110.51 0.0010427 32527700.0 227642.0 259705.0 237369.0 209734.0 235296.0 233228.0 235998.0 224359.0 212194.0 150340.0 True False 224395.78333556952 259103.66902872804 217853.43709083783 225158.5380121143 221456.35188973494 223253.38212102256 248216.82169291755 234783.53820279814 188294.4772181199 176326.0686845422 1.272618308850445 1.4694575280997155 1.2355146276220255 1.2769441279549893 1.2559478785064588 1.2661393961005056 1.40771482937666 1.3315304988897576 1.067876568807247 1.0 17.42788625812291 -8.336654756320886 4.064318160143883 1.0084067518704871 1.315658206361811 0.7221092327412503 0.07001298411320012 0.11907486352754743 3.550942561614022 0.06775637157740447 0.018163738502453036 4.606226013699701e-09 8.336654756320886 0.30725145449132385 SVS(ph)VDIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVSVDIR 7 0 Q6UB99 Q6UB99 ANKRD11 Ankyrin repeat domain-containing protein 11 1 S(0.137)VS(0.863)VDIR 93.14299999999999 0.016388999999999997 0.0 78257.0 82619.0 75890.0 91746.0 109150.0 86287.0 98133.0 104680.0 88471.0 79082.0 True False 91504.36445379548 90820.86831005072 77699.50541442774 86605.76906454518 87762.8410398309 81761.95782041791 88837.13181860554 101932.26091762782 89764.72100431191 93418.94058723225 0.9795054822779864 0.9721890201189392 0.831731819329228 0.9270686278407846 0.9394544670294155 0.8752182084967091 0.9509541776022569 1.0911305595726173 0.9608835257609444 1.0 16.51142746397023 -7.537291356949653 23.774583122547416 1.0198127903847876 0.9196716304165414 0.42219526599931745 0.05044322395877984 123.47319228200969 203672.82325920303 0.023500383503771947 0.013577347327866616 2.9020750740430935e-08 7.537291356949653 -0.10014115996824613 SVS(ph)VDIR ddPTM_PC-9_Lapatinib_30min_R1 2 SVSVDIR 7 0 Q6UB99 Q6UB99 ANKRD11 Ankyrin repeat domain-containing protein 11 1 S(0.161)VS(0.839)VDIR;S(0.028)VS(0.972)VDIR 95.815 0.013005000000000001 10365100.0 175600.0 147870.0 170069.0 118816.0 202271.0 172439.0 193569.0 170183.0 196286.0 174933.0 True False 173095.91179890395 147527.61610010575 156086.583305325 127554.12499855696 190373.81746008675 165064.185944942 203591.05567960904 178090.32346358578 174178.2036967865 205169.9359664294 0.8436709354299672 0.7190508463396154 0.7607673247549506 0.6216998820890981 0.9278835934872854 0.804524235811773 0.9923045241527068 0.8680137400477891 0.8489460352772452 1.0 17.64645981936922 -6.282097962646351 24.99353252572058 0.8994929539152925 0.7368132168994408 0.5468152850684382 0.07592472374238333 629.9407028076621 762124.0194614446 0.022781647437848763 0.02586069966806739 5.222783667749262e-07 6.282097962646351 -0.1626797370158517 SVS(ph)VDSGEQR ddPTM_PC-9_AZD4547_30min_R2 2 SVSVDSGEQR 10 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 S(0.002)VS(0.996)VDS(0.002)GEQR;S(0.018)VS(0.973)VDS(0.009)GEQR 126.66 0.00033883 97855000.0 75113.0 68389.0 97099.0 126706.0 103713.0 85362.0 67160.0 94219.0 71545.0 76374.0 True False 98997.3715525432 90494.40683021434 95811.40381664035 97495.88928818567 89314.24016669217 80024.30064572106 73137.10989384048 79659.61848723066 75326.72263798756 73700.16950643624 1.3432448285468022 1.2278724382351855 1.3000160577415378 1.3228719817214443 1.211859358870163 1.0858089090111593 0.9923601313759991 1.0808607228545652 1.0220698696141977 1.0 16.16938031699481 -6.712299449478521 2.3484459151320034 1.030503199996193 1.2930849114674672 0.9211649816920173 0.03676819231365054 0.07530767412770414 0.8512056431839512 0.013551200751433444 0.012909795644707692 1.93954808269988e-07 6.712299449478521 0.26258171147127407 SVS(ph)VDSGEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVSVDSGEQR 10 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 SVS(0.822)VDS(0.178)GEQR;S(0.042)VS(0.958)VDSGEQR 118.77 0.00084579 45265000.0 40076.0 46754.0 48778.0 45582.0 73731.0 63696.0 96985.0 71468.0 83826.0 67420.0 True False 46860.075262919774 51395.42813357845 49941.052511595146 43028.1883188379 59283.9398324121 60355.66962960046 87797.87868940554 69592.04072660534 85051.7966667886 79642.7123035736 0.5883786966509068 0.6453249349127492 0.6270636831306694 0.5402652304811976 0.7443736924282526 0.7578304139058343 1.1023968942035391 0.8738029973331624 1.067916877850634 1.0 16.28125473371037 -6.928656223423266 1.8089092870961876 1.0027039858944264 0.6112041401132814 0.8519642654591963 0.07493748907037914 0.12084238552435063 0.8058508817864763 0.03132687109845408 0.025278034050199277 1.1785385057942388e-07 6.928656223423266 -0.39149984578114505 SVS(ph)VDSGEQR ddPTM_PC-9_Lapatinib_30min_R1 2 SVSVDSGEQR 10 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 S(0.001)VS(0.999)VDSGEQR;S(0.001)VS(0.998)VDS(0.001)GEQR 158.06 0.00040998 34777700.0 42813.0 43778.0 46430.0 36434.7 81109.0 102375.0 111275.0 100896.0 115197.0 83851.0 True False 42202.47876905738 43676.634730712314 42612.70462498299 39114.229380596196 76338.3280864294 97996.6598977811 117036.2750272433 105583.9964989569 102222.30078181195 98344.53362556567 0.42912887186732673 0.44411858107950924 0.43330018511476653 0.3977265226506504 0.7762335665455276 0.9964627039759112 1.1900638572637303 1.0736132716939262 1.0394304290567933 1.0 16.585557243639833 -6.530328803539236 2.1764620478112175 1.0811081453996847 0.4235811628829913 0.9694028510356578 0.053031659191858066 0.04874237694667899 0.4647116508771053 0.019760299362980096 0.021191251209462445 2.948975717285206e-07 6.530328803539236 -0.6575269825166934 down SVS(ph)VVTGSEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SVSVVTGSEQK 11 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 S(0.036)VS(0.964)VVTGSEQK;S(0.016)VS(0.984)VVTGSEQK;S(0.159)VS(0.84)VVTGS(0.001)EQK 185.57 0.001104 83716000.0 170218.0 165530.0 111390.0 144882.0 165992.0 144461.0 201688.0 216997.0 179099.0 148928.0 True False 199032.54544125384 181962.7244503406 114045.96004892762 136764.7312537812 133467.05918354247 136885.21085094378 182582.65254533032 211301.05867732698 181717.9840529803 175927.46748660094 1.1313329765087003 1.034305370559599 0.6482555662185817 0.777392713074765 0.7586482150304792 0.7780775384683423 1.0378291414854606 1.201069177520106 1.032914226806683 1.0 17.42462122224415 -7.385880833689162 5.04072080542703 1.0928407649121572 0.8462957491240118 0.35508014864919835 0.14050858173521144 0.258847984738243 9.543372770581325 0.06591393944420766 0.04354741417725582 4.1126255219041555e-08 7.385880833689162 -0.24654501578814536 SVS(ph)VVTGSEQK ddPTM_PC-9_Lapatinib_30min_R1 2 SVSVVTGSEQK 11 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 S(0.309)VS(0.691)VVT(0.001)GSEQK;S(0.02)VS(0.953)VVT(0.004)GS(0.023)EQK 131.06 0.00017779 95701000.0 192138.0 146899.0 142829.0 123347.0 184816.0 177966.0 224353.0 182329.0 194982.0 146059.0 True False 189398.07688620614 146558.86439094768 131086.15095588422 132418.34985352983 173945.48624223625 170354.80903900845 235968.90057233995 190800.67096473943 173021.07390851522 171305.10353861604 1.1056184140101322 0.8555428960580267 0.7652203480693991 0.7729971093574556 1.0154133335731297 0.9944526200330431 1.3774773529683384 1.113806109820474 1.0100170417252767 1.0 17.38620860741257 -6.700346041295507 2.332315345697074 1.1332151127807883 0.8700836545164968 0.3680043093141332 0.13642065497169298 0.295607630655255 3.2937822631310496 0.05291364095552036 0.050782660106467044 1.9936731440509622e-07 6.700346041295507 -0.2631314582642915 SVSASSGPCS(ph)PAAPHPPPPPR ddPTM_PC-9_AZD4547_30min_R2 1 SVSASSGPCSPAAPHPPPPPR 21 0 Q86UY5 Q86UY5 FAM83A Protein FAM83A 1 S(0.037)VS(0.115)AS(0.082)S(0.259)GPCS(0.507)PAAPHPPPPPR 65.67699999999999 0.0023993 4326100.0 13086.0 10812.0 16103.0 21623.0 21453.0 19139.0 16820.0 22307.0 20942.0 22741.0 True False 17247.07579429097 14306.767559816282 15889.46369848671 16638.1514220198 18474.621255735026 17942.235304449903 18316.94741534244 18859.96571386513 22048.95136605964 21944.84451182168 0.7859283662274288 0.6519420792482367 0.7240636264215525 0.7581804196906856 0.8418661269521757 0.8176059436094171 0.8346811209108868 0.8594258074467228 1.004744023325473 1.0 14.421594427700139 -7.454100281053651 0.4506856391600685 1.0160218646343522 0.6992909485596441 0.8134343652075618 0.045424568559584606 0.42661187472797124 0.20232804460456935 0.0483091913808032 0.04375869285839945 3.514792726044401e-08 7.454100281053651 -0.31673091607470805 SVSASSGPCS(ph)PAAPHPPPPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVSASSGPCSPAAPHPPPPPR 21 0 Q86UY5 Q86UY5 FAM83A Protein FAM83A 1 S(0.003)VS(0.003)AS(0.049)S(0.043)GPCS(0.903)PAAPHPPPPPR 80.061 0.0039138 0.0 8302.1 8068.0 13079.0 16643.0 15352.0 16824.0 13444.0 13337.0 16178.0 11298.0 True False 9707.481556050667 8868.937720445545 13390.852962383713 15710.546667334009 12343.885805254115 15941.719823040672 12170.486993868857 12986.917881719573 16414.572644230953 13346.237965081213 0.7273571459949311 0.6645271681540542 1.0033428893909453 1.1771516968630948 0.9248962769546273 1.1944729192413786 0.9119039406993519 0.9730770510535062 1.2299025903162868 1.0 13.704145512174183 -5.311393199623632 4.997931833375786 1.0534280575271093 0.6945251808218922 0.638823843790908 0.10739420969553828 0.11023236998661515 6.288037478153622 0.027130213166115955 0.06065049899866008 4.882101456386918e-06 5.311393199623632 -0.35890287670521714 SVSDYDGK ddPTM_PC-9_Lapatinib_30min_R1 1 SVSDYDGK 8 0 P07237;H7BZ94;I3L398;I3L312;I3L4M2 P07237 P4HB Protein disulfide-isomerase 0 90.65700000000001 0.0379 0.0 25125.0 28888.0 26554.0 24770.0 27946.0 29231.0 28725.0 28698.0 30449.0 22703.0 False True 24766.712892639287 28821.111610873435 24370.832621404214 26591.668430297712 26302.271223949945 27980.858270789126 30212.23994749556 30031.413847199772 27019.512977815284 26627.183300154025 0.9301289067438095 1.0823943068250377 0.915261383327137 0.9986662175470844 0.9877977301413552 1.0508380835995998 1.1346389742741132 1.1278479405302346 1.014734178724003 1.0 14.700612203748612 -6.856471833731018 3.730199410487105 1.0813797863261565 0.9850762416925786 0.33092039393701855 0.05807328052518113 0.2448581055001551 6.538049523802215 0.02058970144009334 0.018230864764537526 1.3916440473142406e-07 6.856471833731018 -0.09630354463357793 SVSEINS(ph)DDELSGK ddPTM_PC-9_AZD4547_30min_R2 1 SVSEINSDDELSGK 14 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 S(0.003)VS(0.224)EINS(0.564)DDELS(0.209)GK 126.63 0.0006494 0.0 7878.2 7359.0 10081.0 11471.0 9112.2 10647.0 7166.8 7527.9 8261.0 8930.8 True False 10383.303723260215 9737.652836911593 9947.319353191611 8826.538175183323 7847.128318021203 9981.241406890542 7804.631316068734 6364.636028932855 8697.65959483424 8618.135410323961 1.2048202109729789 1.1299025106111147 1.1542310348564928 1.0241818856326752 0.9105366699879023 1.158167159329345 0.9056055567100162 0.7385165962127305 1.0092275394530255 1.0 13.073160051277952 -5.841962597706348 0.6244988991862916 0.9120102230892556 1.231517010065289 0.45694133447014196 0.1010571672181809 1.127841751820273 0.7596880999178082 0.063846297658446 0.22018489011386702 1.4389224957508596e-06 5.841962597706348 0.3195067869760334 SVSEINS(ph)DDELSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SVSEINSDDELSGK 14 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 S(0.217)VS(0.079)EINS(0.704)DDELSGK;SVS(0.058)EINS(0.804)DDELS(0.138)GK;S(0.228)VSEINS(0.77)DDELS(0.001)GK;S(0.379)VS(0.001)EINS(0.62)DDELSGK 222.09 2.3731e-16 37859700.0 93047.0 96070.0 102903.0 111205.0 123143.0 103224.0 107082.0 98630.0 95160.0 80989.0 True False 108798.01933798046 105607.19469548858 105356.59778180091 104974.54438147448 99014.0131394218 97810.7517245334 96938.4177534563 96041.06700712332 96551.53497496709 95671.66459142859 1.1372021151989853 1.1038502899107092 1.1012309468193366 1.0972375658955489 1.034935616122777 1.0223586277320449 1.0132406305193649 1.0038611475745958 1.0091967709279026 1.0 16.545804079532225 -6.281254889046936 1.123105312838658 1.005329491163835 1.1209350780806748 0.9633745245499591 0.009364335235053325 0.0836058512049543 0.2191262025409093 0.0039955999848349435 0.00584387788882611 5.232932237028171e-07 6.281254889046936 0.11560558691683975 SVSEINS(ph)DDELSGK ddPTM_PC-9_Lapatinib_30min_R1 3 SVSEINSDDELSGK 14 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 SVSEINS(0.994)DDELS(0.006)GK;SVS(0.001)EINS(0.955)DDELS(0.044)GK;S(0.022)VS(0.051)EINS(0.924)DDELS(0.003)GK 214.63 2.6013000000000003e-15 80579700.0 86546.0 98223.0 103099.0 94907.0 110424.0 100624.0 91392.0 100968.0 100645.0 85508.0 True False 85311.83816940739 97995.57067830331 94622.59819364872 101886.77738047077 103929.07742193688 96320.54608600058 96123.83057550955 105659.34188180564 89309.30026116516 100287.94386775211 0.8506689326675853 0.9771420860669782 0.943509205038901 1.0159424298779822 1.0363067923596705 0.9604399329695774 0.958478425903978 1.053559758101499 0.890528779600225 1.0 16.613788656980773 -3.9618381689269486 1.4190712179502156 0.986833815889079 1.0299565052123084e-07 0.42378363890889337 0.04548458408096169 10.065137195374191 3.191649739117516 0.01233002753526399 24.69174317533647 0.0001091847115445214 3.9618381689269486 -0.9868337128934285 SVSENS(ph)LVAMDFSGQTGR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSENSLVAMDFSGQTGR 18 0 A0A2R8YCL1;Q13322-3;Q13322-2;Q13322-4;Q13322 A0A2R8YCL1 GRB10 Growth factor receptor-bound protein 10 1 S(0.001)VS(0.117)ENS(0.882)LVAMDFSGQTGR 159.4 7.0137e-06 8949700.0 68519.0 64333.0 65979.0 67417.0 79738.0 77213.0 69731.0 85518.0 94754.0 67078.0 True False 67541.90649515425 64184.04089110777 60554.46130630526 72375.07107651935 75047.96761093962 73910.7799822941 73341.3299835966 89491.47847880803 84081.80671614532 78672.3429241834 0.8585216098145755 0.8158399572892088 0.7697045626906224 0.9199557098009306 0.953930756622609 0.939476024675177 0.9322377757870476 1.137521461195722 1.0687594088455588 1.0 16.26356892838504 -6.729013631122658 0.7303409043264383 1.0662596259763435 0.8126221611754395 0.7086601558820954 0.056842399799983304 0.3820387761291468 0.4492190215756046 0.042484274800252235 0.04389467067178162 1.8663211120308783e-07 6.729013631122658 -0.253637464800904 SVSGS(ph)PEPAAK ddPTM_PC-9_AZD4547_30min_R2 4 SVSGSPEPAAK 11 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 S(0.126)VS(0.228)GS(0.646)PEPAAK;SVS(0.013)GS(0.987)PEPAAK;SVS(0.002)GS(0.998)PEPAAK;S(0.002)VS(0.038)GS(0.961)PEPAAK 154.67 6.3822e-05 111070000.0 385510.0 339586.0 453943.0 532942.0 499843.0 401986.0 376672.0 449293.0 379412.0 414049.0 True False 508094.16089386394 449350.53353383 447923.4192189133 410080.4557718207 430448.42736821715 376849.7518728565 410195.07828964805 379865.09057603445 399466.9437350501 399553.2705367077 1.2716556173131972 1.1246323498496988 1.121060575019775 1.0263473884745633 1.0773242496301154 0.9431777428993279 1.0266342651598008 0.9507245180743316 0.9997839416968314 1.0 18.608028338079862 -1.522878757449799 0.41284169211301863 0.9776375377962678 6.124339931445632 0.8507977210822221 0.036177412538289246 25.005139372146097 0.3246067772515344 0.023333872933422088 105.71878739509201 0.029999999159363393 1.522878757449799 5.146702393649364 SVSGS(ph)PEPAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SVSGSPEPAAK 11 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 S(0.003)VS(0.007)GS(0.989)PEPAAK;SVS(0.012)GS(0.988)PEPAAK;S(0.018)VS(0.001)GS(0.982)PEPAAK;SVS(0.001)GS(0.999)PEPAAK;S(0.064)VS(0.204)GS(0.732)PEPAAK 158.01 6.2859e-05 73963800.0 334400.0 347337.0 351604.0 406896.0 422056.0 398685.0 385029.0 381762.0 364242.0 330089.0 True False 391007.31529894134 381818.321889737 359987.5728255953 384098.9362946298 339357.1565543465 377777.2567551691 348556.2657514385 371741.15201027464 369568.35017183656 389931.52271691343 1.002758926938074 0.9791932676521089 0.9232071578038149 0.9850420238362775 0.8702993648469826 0.9688297425223346 0.8938909666056597 0.9533498328632312 0.9477775677042137 1.0 18.572861263768594 -5.06878388399573 3.7348456362589926 0.9392992531054386 0.9996537782474161 0.21465062767365817 0.03748675728480156 0.29452951876329064 7.792708977650402 0.009000677226906345 0.03153218327120062 8.535247440242623e-06 5.06878388399573 0.06035452514197748 SVSGS(ph)PEPAAK ddPTM_PC-9_Lapatinib_30min_R1 3 SVSGSPEPAAK 11 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 SVS(0.001)GS(0.999)PEPAAK;S(0.01)VSGS(0.989)PEPAAK;S(0.01)VS(0.001)GS(0.989)PEPAAK 174.05 6.2859e-05 83167000.0 401570.0 347580.0 367284.0 345376.0 394710.0 364819.0 306568.0 317114.0 379000.0 315270.0 True False 395843.5381610814 346775.1998652519 337087.3272772395 370776.1031805617 371493.9338297176 349216.5418046258 322440.5909912553 331848.2741215734 336313.0289530687 369763.99942913087 1.0705302267722494 0.9378284538263033 0.9116283029112082 1.0027371614137488 1.0046784825003447 0.9444308865756869 0.8720172636845746 0.8974596624709421 0.9095342690805318 1.0 18.49624524386973 -6.996852783260569 7.502899558056031 0.910703741074564 0.9793119582904938 0.265552606282878 0.050461732069241316 0.16554875318863993 66.43461929979176 0.018295036661787008 0.01549191334313332 1.0072730554703061e-07 6.996852783260569 0.0686082172159298 SVSGS(ph)PESDELQELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVSGSPESDELQELR 15 0 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 S(0.001)VS(0.049)GS(0.787)PES(0.163)DELQELR;SVS(0.005)GS(0.947)PES(0.047)DELQELR 159.18 2.0571e-14 3301700.0 16311.2 12085.400000000001 16645.0 16837.0 18014.3 17597.5 14519.2 13091.6 11732.7 11069.0 True False 19072.363999115114 13285.158642373888 17041.879926514015 15893.677476290506 14484.527231734568 16674.656121371743 13143.836266094953 12747.959371696787 11904.268541412312 13075.722077844204 1.4586088543004254 1.0160172083256922 1.3033222811755962 1.2155104996626618 1.1077420539763134 1.2752378814800334 1.0052092104623547 0.9749334909233972 0.9104100309368895 1.0 13.674602997865689 -7.359837443030921 4.658578197033445 0.9632576582999158 1.2166522094000194 0.5553292881346417 0.11248545549043883 0.1749597345754251 6.282629840143987 0.04591218530869939 0.030335656323803518 4.366792512455225e-08 7.359837443030921 0.25339455110010356 SVSGS(ph)PESDELQELR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSGSPESDELQELR 15 0 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 S(0.012)VS(0.3)GS(0.672)PES(0.016)DELQELR 232.26 1.8460999999999999e-25 3403300.0 8608.8 6345.3 6970.2 6277.6 7752.1 6271.0 5157.0 5656.3 8670.8 5522.8 True False 8486.036933339434 6330.607847704073 6397.137061750077 6739.275645459703 7296.136719214996 6002.8039484149895 5424.004226605209 5919.112347338353 7694.203196428158 6477.408621331573 1.3100975142116236 0.9773364963970234 0.9876074578162101 1.0404277450191644 1.126397475556377 0.9267292368504276 0.8373725580230857 0.913808699337784 1.187852063414589 1.0 12.661201042696685 -6.767532285519378 24.999670031487188 0.9592792996011407 1.0739428783088907 0.17373028757614306 0.12178768373044487 277.3152895757037 1137837.998449037 0.04308288316653469 0.03896224568322511 1.70792074824597e-07 6.767532285519378 0.11466357870775001 SVSGSPES(ph)DELQELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVSGSPESDELQELR 15 0 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 S(0.018)VS(0.018)GS(0.4)PES(0.564)DELQELR 137.21 3.9398000000000005e-05 3596800.0 5371.0 7135.2 7058.6 6986.6 5075.9 3955.7 4839.2 4382.4 4371.9 3812.0 True False 6280.204217914517 7843.535501105976 7226.903793889571 6595.163452862815 4081.3138326530307 3748.256128388137 4380.795943225985 4267.366643536619 4435.830766677791 4503.085424224601 1.3946446994164947 1.741813614929718 1.6048782363781142 1.4645876841207057 0.9063371995337626 0.8323750884724909 0.9728431798471436 0.9476539398031582 0.985064760889276 1.0 12.136698130748739 -6.187490126409394 3.829529321111012 0.9324285735007445 1.587802181533137 0.9143553325332678 0.09189428001466932 0.06062743199314444 1.7241202547544394 0.028083079132103818 0.036552544047095126 6.493963952942167e-07 6.187490126409394 0.6553736080323924 SVSGSPES(ph)DELQELR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSGSPESDELQELR 15 0 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 S(0.016)VS(0.319)GS(0.319)PES(0.346)DELQELR 107.11 0.00087342 3579200.0 10446.0 10284.0 10263.0 9168.2 9019.9 7762.4 6780.4 6418.2 8102.6 6298.4 True False 10297.03812443821 10260.188029847077 9419.215756325653 9842.460012218633 8489.367215805705 7430.420247038195 7131.455935248004 6716.41300279105 7189.999863839412 7387.070047909531 1.3939272347027725 1.3889387759021738 1.275094955812853 1.3323902370472245 1.1492198071423614 1.005868388799282 0.9653970909976867 0.9092120366032983 0.9733222803097842 1.0 12.850786542737387 -6.501008333098518 1.4081104249479228 0.9496887313664613 1.3645742577487632 0.9595468492757238 0.03658774134213635 0.07256760652843976 0.29535646779801533 0.015228466705049301 0.017244546657433014 3.154944086772809e-07 6.501008333098518 0.4148855263823019 SVSLT(ph)IY ddPTM_PC-9_Lapatinib_30min_R1 1 SVSLTIY 7 0 P30291;P30291-2 P30291 WEE1 Wee1-like protein kinase 1 S(0.001)VS(0.275)LT(0.671)IY(0.053) 88.94200000000001 0.0043396 2262600.0 37008.0 27941.0 30202.0 28477.0 31271.0 32077.0 35057.0 27712.0 33243.0 31878.0 True False 36480.259133564 27876.30433118994 27718.908143091452 30571.293576487205 29431.701261151455 30705.14148513917 36872.07992478162 28999.600687629783 29498.82327569097 37388.069825235005 0.975719241567847 0.7455935666509022 0.7413837695462585 0.8176750958096577 0.7871949902395492 0.8212550588641192 0.9861990762597452 0.775637812360577 0.7889902691842304 1.0 15.19029037293222 -7.021597692248653 24.65873026973011 0.8739695296588912 0.8057901085578352 0.12468615375753389 0.0908319842773334 1527.6836252139692 1744197.9100878723 0.03420829230257646 0.026768627540321124 9.514857923376771e-08 7.021597692248653 -0.06817942110105601 SVSMLS(ph)LNTPNSNR ddPTM_PC-9_AZD4547_30min_R2 1 SVSMLSLNTPNSNR 14 0 Q9H8V3-2;Q9H8V3-4;Q9H8V3;Q9H8V3-3;H7C3G1 Q9H8V3-2 ECT2 Protein ECT2 1 SVS(0.007)MLS(0.925)LNT(0.067)PNS(0.001)NR 74.53699999999999 0.016327 10699000.0 17632.0 19917.0 23542.0 34786.0 27534.0 28785.0 20315.0 27928.0 20144.0 39837.0 True False 23238.609231616883 26354.780751836963 23229.817697930455 26766.625138342537 23711.37937143564 26985.06939958149 22122.995644630293 23612.36932159524 21208.770715208935 38442.318755439104 0.6045059191006503 0.6855668857932273 0.6042772249435066 0.696280193414592 0.6168040882830664 0.7019625837674904 0.575485463958913 0.6142285399538858 0.5517037317684735 1.0 15.230407738452001 -11.125878131593003 6.312467817636521 1.0011513657956002 0.6307955550901794 0.8410940903208992 0.04850999806193618 0.0007695507259228237 4.839812946669124e-05 0.04598419112685003 0.011121255599818894 7.483794755927099e-12 11.125878131593003 -0.3703558107054208 SVSMLS(ph)LNTPNSNR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSMLSLNTPNSNR 14 0 Q9H8V3-2;Q9H8V3-4;Q9H8V3;Q9H8V3-3;H7C3G1 Q9H8V3-2 ECT2 Protein ECT2 1 SVS(0.003)MLS(0.863)LNT(0.122)PNS(0.012)NR 96.665 0.0025479 10818000.0 36530.0 32306.0 48042.0 41039.0 41333.0 39023.0 35737.0 30665.0 43637.0 33254.0 True False 36009.07550121846 32231.197441874734 44092.17220748292 44057.14496209073 38901.87420380462 37354.077257056 37587.286997516036 32089.807848086304 38722.141542018646 39001.90959183028 0.9232644216159425 0.8264004962625265 1.1305131638149046 1.1296150732916772 0.9974351156373479 0.9577499575785016 0.9637294017365098 0.8227752995665666 0.9928268114884755 1.0 15.251257141760723 -6.984237908901239 2.5154226146699457 0.9307256157088376 1.0054766395526924 0.06766095866854771 0.09553280422123166 0.7517619066570108 9.593527917064232 0.04290130983738924 0.034559133073207106 1.0369602077043038e-07 6.984237908901239 0.07475102384385479 SVSMLSLNT(ph)PNSNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SVSMLSLNTPNSNR 14 0 Q9H8V3-2;Q9H8V3-4;Q9H8V3;Q9H8V3-3;H7C3G1 Q9H8V3-2 ECT2 Protein ECT2 1 SVSMLS(0.051)LNT(0.943)PNS(0.006)NR;SVSMLS(0.001)LNT(0.988)PNS(0.011)NR;SVSMLS(0.001)LNT(0.999)PNSNR 108.66 0.0025385 21161900.0 81047.0 74910.0 82861.0 90446.0 105276.0 85142.0 91191.0 87671.0 78757.0 71224.0 True False 94766.65634878399 82346.56973705701 84836.72049209224 85378.60384988858 84647.92353008954 80677.00363607517 82552.72831433329 85369.72914510292 79908.67213139439 84136.34739112631 1.1263462140594285 0.9787276520841922 1.0083242632070784 1.0147648013882438 1.0060803226527657 0.9588840749293569 0.9811779435892168 1.0146593213542174 0.9497520941801925 1.0 16.36044156733655 -4.758200701041666 24.999976497017414 0.9912813117589367 1.1263464002909083 0.7792994165103132 0.021719637206825945 41.8522241148799 323011.82872528856 0.0054137702519608125 0.037776536490872384 1.745015540382171e-05 4.758200701041666 0.13506508853197152 SVSMLSLNT(ph)PNSNR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSMLSLNTPNSNR 14 0 Q9H8V3-2;Q9H8V3-4;Q9H8V3;Q9H8V3-3;H7C3G1 Q9H8V3-2 ECT2 Protein ECT2 1 SVS(0.002)MLS(0.041)LNT(0.801)PNS(0.155)NR 80.719 0.043039 11576000.0 74031.0 60951.0 65639.0 64805.0 66990.0 52765.0 50156.0 44116.0 63166.0 45448.0 True False 72975.30436437721 60809.87170431827 60242.41479386721 69570.97588314272 63049.779907407334 50508.36395122262 52752.83226480719 46165.79041337598 56051.57991253184 53303.626244346575 1.3690495282601347 1.1408205405306326 1.1301747936943891 1.3051827949608112 1.1828422257499684 0.9475596222982968 0.989666857241297 0.8660909897902558 1.0515528466222637 1.0 15.701946062379683 -6.710203888917784 4.900629741573944 0.9631484336437286 1.223703559850363 0.7195492945870305 0.07967790582392585 0.1075542655775962 5.474106145239237 0.026642491942848352 0.0260300484523526 1.9489294179704778e-07 6.710203888917784 0.26055512620663435 SVSPQGNS(ph)VDR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSPQGNSVDR 11 0 B0QY04;A0A494BZS1;A0A0G2JR51;A0A217FLJ2;Q15080;Q15080-3 B0QY04 NCF4 Neutrophil cytosol factor 4 1 S(0.021)VS(0.06)PQGNS(0.919)VDR 100.02 0.00432 2479800.0 8271.3 7616.8 10237.0 6992.1 9858.5 10083.0 9790.7 9274.7 11112.0 6553.0 True False 8153.349745229353 7599.163767574799 9395.353375962748 7506.322358961837 9278.642412556737 9651.773594621009 10297.614539736986 9705.636420956987 9860.449545452508 7685.677318676364 1.0608498649060552 0.9887435358636076 1.2224496275860859 0.9766637405816284 1.2072641132108726 1.2558130135345376 1.3398447674499105 1.2628212216732126 1.2829642901467382 1.0 12.907956691128135 -6.432980795499122 5.6314599761161785 1.2498214905651572 1.0689978563165905 0.35639212892676486 0.10512914224203233 0.2254649313827728 11.110914964232727 0.031388632862161765 0.03543671550078495 3.6899391511937054e-07 6.432980795499122 -0.18082363424856673 SVSPS(ph)PSVLSEGR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSPSPSVLSEGR 13 0 C9IYE1;A0A087X1P3;Q86UW7-3;Q86UW7-2;Q86UW7 C9IYE1 CADPS2 Calcium-dependent secretion activator 2 1 S(0.005)VS(0.213)PS(0.782)PSVLSEGR 115.24 0.00029243 3971100.0 15321.0 17866.0 18457.0 16020.0 21417.0 21752.0 17308.0 17396.0 18905.0 14968.0 True False 15102.519730472697 17824.632374683762 16939.53670608036 17198.164241153383 20157.29416744206 20821.71766638859 18204.123551305587 18204.28166722027 16775.719821524457 17555.198856393676 0.8602875908165687 1.0153477907310606 0.9649299244429185 0.9796621719776043 1.1482236306369547 1.1860713078055072 1.036964815962513 1.0369738227482508 0.9555983933166711 1.0 14.099610717978777 -3.764043202538841 0.7812623350465454 1.05700543120517 0.14737034827325798 0.3659470586731457 0.07091251794064678 12.667126882669816 1.7953434988394623 0.028590037323111144 14.543272124183828 0.00017216972962864367 3.764043202538841 -0.909635082931912 SVSPS(ph)PVPLLFQPDQNAPPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVSPSPVPLLFQPDQNAPPIR 21 0 Q02241-2;Q02241-3 Q02241-2 KIF23 Kinesin-like protein KIF23 1 S(0.037)VS(0.27)PS(0.694)PVPLLFQPDQNAPPIR 118.66 2.4902e-06 59295000.0 25559.0 18199.0 23817.0 24156.0 26656.0 19017.0 21968.0 25023.0 17810.0 15810.0 True False 29885.633886739382 20005.676446999067 24384.887606475502 22802.61763480864 21432.94815169709 18019.71504248481 19887.032005453057 24366.172764060055 18070.43755679029 18676.22784810887 1.6001964706039695 1.0711839997724604 1.3056644952500236 1.2209434271341686 1.1476058402161422 0.9648476763635899 1.064831301437929 1.3046624276715142 0.967563562821926 1.0 14.188915474084531 -3.0009540730569233 1.7227112601382968 1.1245240307022728 199.99999999507307 0.5620118596479324 0.12508356654943822 447.6328572125521 4.074505083318987 0.03408544966967923 349552.39696474024 0.0009978055768761415 3.0009540730569233 198.8754759643708 SVSPS(ph)PVPLLFQPDQNAPPIR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSPSPVPLLFQPDQNAPPIR 21 0 Q02241-2;Q02241-3 Q02241-2 KIF23 Kinesin-like protein KIF23 1 S(0.02)VS(0.249)PS(0.73)PVPLLFQPDQNAPPIR 61.015 0.0091766 107950000.0 10323.0 10833.0 14585.0 8661.4 12035.0 10288.0 8738.7 11587.0 12818.0 11292.0 True False 10175.792126993656 10807.916854077537 13385.877599728125 9298.388249583386 11327.124961720381 9848.006222499347 9191.14712721251 12125.374320423154 11374.301860476096 13243.80715435578 0.7683434233370667 0.8160732580980614 1.010727311543918 0.7020932984912289 0.8552770989265713 0.7435932966798311 0.6939958442531095 0.915550504405768 0.8588392844979762 1.0 13.693030288187686 -8.564989560417475 1.4260040220738146 0.9955163927150348 0.8078558190873185 0.28653561600587596 0.09107341258933782 0.634082179455539 2.8252528300350646 0.08744332030753225 0.02602526751831557 2.722766757232371e-09 8.564989560417475 -0.18766057362771627 SVSPS(ph)PVPLSSNYIAQISNGQQLMSQPQLHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVSPSPVPLSSNYIAQISNGQQLMSQPQLHR 31 0 Q02241;H7BYN4 Q02241 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 S(0.077)VS(0.073)PS(0.585)PVPLS(0.082)S(0.082)NY(0.069)IAQIS(0.011)NGQQLMS(0.02)QPQLHR 59.275 0.00071558 10703000.0 11865.0 14393.0 19720.0 18277.0 23368.0 17789.0 22450.0 16631.0 17863.0 11485.0 True False 13873.510155568012 15821.841919976783 20190.19958851646 17252.998944833493 18789.2081485916 16856.11352425527 20323.373476075256 16194.453872001066 18124.212581524138 13567.139584790026 1.0225818101791666 1.1661884821848874 1.488169224053055 1.2716754948239528 1.3849056413966565 1.2424220609591485 1.497985138949965 1.1936527792605962 1.3358904777424858 1.0 13.727828963104084 -5.013150126493267 6.088050369772653 1.3166674643429492 1.0527166176563962 0.2853253159817577 0.13831091167337647 0.1463482283856754 23.28451258032965 0.03206455052191983 0.10385005936363818 9.701745402841857e-06 5.013150126493267 -0.263950846686553 SVSPS(ph)PVPLSSNYIAQISNGQQLMSQPQLHR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSPSPVPLSSNYIAQISNGQQLMSQPQLHR 31 0 Q02241;H7BYN4 Q02241 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 S(0.107)VS(0.31)PS(0.316)PVPLS(0.098)S(0.098)NY(0.07)IAQISNGQQLMSQPQLHR 60.101000000000006 0.00060879 5060700.0 11918.0 9501.8 15516.0 9287.5 9343.5 13977.0 10136.0 11097.0 14394.0 7949.5 True False 11748.047134506476 9479.799165888846 14240.334373492053 9970.533732191761 8793.933700027777 13379.236291978363 10660.792484171101 11612.607131590206 12772.796144460357 9323.560482957071 1.260038711174902 1.0167574054158142 1.5273493854115667 1.0693912213491101 0.943194793030257 1.4349921702588655 1.143425036353699 1.2455120715758083 1.3699483333441436 1.0 13.186665281406471 -6.78124168126747 24.999771665693057 1.2481604710238727 1.170204961410418 0.03798079223168871 0.1852468743428302 985.2312110849755 1243815.0152861092 0.06431962585656757 0.05679887480712057 1.6548487975890334e-07 6.78124168126747 -0.07795550961345477 SVSPSPVPLS(ph)SNYIAQISNGQQLMSQPQLHR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSPSPVPLSSNYIAQISNGQQLMSQPQLHR 31 0 Q02241;H7BYN4 Q02241 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 S(0.015)VS(0.173)PS(0.055)PVPLS(0.34)S(0.34)NY(0.078)IAQISNGQQLMSQPQLHR 84.68299999999999 5.7905e-09 3666800.0 23309.0 21131.0 27373.0 21374.0 22364.0 26650.0 17414.0 20600.0 29680.0 16650.0 True False 22976.6093856529 21082.072467784783 25122.497602835625 22945.9152615738 21048.593489315692 25510.241624184244 18315.611712643607 21557.151203997328 26337.125855744303 19527.930315269554 1.1766023851327811 1.0795856052036397 1.286490539306743 1.1750305788233792 1.0778711901105607 1.3063464080592768 0.9379187357260286 1.103913771504042 1.3486900777780022 1.0 14.25325143158398 -7.239414161519238 24.988681427608558 1.1062900555543271 1.178398070067112 0.10568406836187627 0.12097470659106728 2301.6117362561895 2611293.51994228 0.045824660686506195 0.0354706150881118 5.7621669676962835e-08 7.239414161519238 0.07210801451278481 SVSPT(ph)TEMVSNESVDYR ddPTM_PC-9_AZD4547_30min_R2 1 SVSPTTEMVSNESVDYR 17 0 P08581;P08581-2 P08581 MET Hepatocyte growth factor receptor 1 S(0.001)VS(0.082)PT(0.697)T(0.2)EMVS(0.019)NESVDYR 77.191 0.029942 5369000.0 8601.8 11596.0 12795.0 10660.0 9234.6 6046.7 10554.0 14127.0 8491.9 6371.1 True False 11336.993471445212 15344.180227860688 12625.329939895515 8202.501695358229 7952.53519079899 5668.598893119661 11493.285554192864 11943.996756165 8940.764497442551 6148.049728211913 1.8439983364842498 2.4957801101461423 2.053550393706305 1.3341631993832015 1.2935053459809749 0.9220157844702901 1.8694197448424914 1.9427293669010006 1.454244011139914 1.0 12.585913118909147 -5.6885976404761545 5.143375073790466 1.4367371937740179 2.1894312637742996 0.4910897972777859 0.33905011477552 0.18117955601759098 8.695638638940466 0.0984135473118383 0.171899707978352 2.048341478778267e-06 5.6885976404761545 0.7526940700002818 SVSPT(ph)TEMVSNESVDYR ddPTM_PC-9_Lapatinib_30min_R1 2 SVSPTTEMVSNESVDYR 17 0 P08581;P08581-2 P08581 MET Hepatocyte growth factor receptor 1 S(0.005)VS(0.334)PT(0.556)T(0.099)EMVS(0.006)NESVDYR;SVS(0.038)PT(0.559)T(0.27)EMVS(0.133)NES(0.001)VDYR 86.411 0.011727 16725000.0 72345.0 82019.0 36551.9 34041.6 38798.4 30469.0 28064.5 24668.4 43345.3 15837.3 True False 71313.34703355188 81829.09004473215 33546.743876414286 36545.13282344862 36516.35439258928 29165.911896708087 29517.542489346888 25814.58392042171 38463.29586775582 18574.756203124238 3.8392615361248787 4.405392412685807 1.8060395253409458 1.967462314111116 1.9659129839048601 1.570190831996085 1.589121395002864 1.3897670385617094 2.070729513062808 1.0 14.181055654816586 -5.267288465452752 24.13751699309804 1.698575768673319 4.122327109039939 0.900218279561178 0.3264815668014279 69.2383754022938 285729.1547839191 0.08195749951021306 0.17846799731992355 5.403952643957557e-06 5.267288465452752 2.4237513403666204 SVSPTT(ph)EMVSNESVDYR ddPTM_PC-9_AZD4547_30min_R2 1 SVSPTTEMVSNESVDYR 17 0 P08581;P08581-2 P08581 MET Hepatocyte growth factor receptor 1 S(0.001)VS(0.122)PT(0.039)T(0.617)EMVS(0.221)NESVDYR 83.37 0.014719999999999999 11521000.0 14264.0 21737.0 20449.0 22611.0 19348.0 13576.0 15345.0 24581.0 15821.0 13787.0 True False 18799.655290368817 28763.060159797136 20177.832898860746 17398.383286467637 16661.864170790166 12727.090573865493 16710.675272796052 20782.571265186663 16657.265760788345 13304.321326436197 1.4130488003933865 2.161933664563846 1.516637519778376 1.3077242243011962 1.2523648340996096 0.9566132883889594 1.2560336497278746 1.562091801247381 1.252019201286857 1.0 13.699607297729377 -5.596971761495161 3.3779757861337085 1.240282553055817 1.7995692117166944 0.48507075248934306 0.23138998820243306 0.1893839054215845 4.311746473637249 0.06383485234941798 0.12309359595245598 2.5294624606951166e-06 5.596971761495161 0.5592866586608773 SVSS(ph)PTSSNTPTPTK ddPTM_PC-9_AZD4547_30min_R2 3 SVSSPTSSNTPTPTK 15 0 Q5M775;Q5M775-4;Q5M775-2;Q5M775-5;Q5M775-3 Q5M775 SPECC1 Cytospin-B 1 SVS(0.152)S(0.799)PT(0.017)S(0.025)S(0.007)NTPTPTK;SVS(0.036)S(0.957)PT(0.003)S(0.001)SNT(0.002)PTPTK;S(0.011)VS(0.147)S(0.768)PT(0.031)S(0.031)S(0.01)NT(0.001)PTPTK 144.88 1.2027e-06 36074000.0 82774.7 79628.0 136180.0 175523.0 139022.0 148711.0 130155.0 168721.0 120667.0 142707.0 True False 109095.33277928276 105366.19378959044 134374.1642215688 135058.88415331737 119721.1949943969 139412.07766132217 141738.54285635485 142649.046272876 127045.21127343696 137710.8713666302 0.7922056675455654 0.7651261860733717 0.9757701980101627 0.98074235398415 0.8693663311131112 1.0123534640207368 1.0292473023353523 1.0358590055907702 0.9225503405261459 1.0 17.071282929680436 -5.264396594541778 24.316871631964233 0.9787584167504136 0.7786659082506279 0.735679214564608 0.04784864587399094 82.23826194939902 676247.0221361887 0.013106544790652009 0.029345251877535533 5.4400564397265026e-06 5.264396594541778 -0.20009250849978577 SVSS(ph)PTSSNTPTPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SVSSPTSSNTPTPTK 15 0 Q5M775;Q5M775-4;Q5M775-2;Q5M775-5;Q5M775-3 Q5M775 SPECC1 Cytospin-B 1 S(0.012)VS(0.077)S(0.819)PT(0.077)S(0.011)S(0.001)NT(0.004)PTPTK;SVS(0.003)S(0.984)PT(0.012)SSNTPTPTK;SVS(0.003)S(0.996)PT(0.001)SSNTPTPTK 214.58 1.1932000000000001e-17 20928400.0 81558.0 93783.0 89982.0 120714.0 147676.0 135483.0 154329.0 148598.0 128240.0 101392.0 True False 95364.15855607366 103093.15644974516 92127.5121386355 113950.78594006851 118739.94790103588 128378.03297580942 139709.83987479826 144697.45995259585 130115.26739375528 119773.5669813699 0.7962037113823871 0.8607337916702499 0.7691806669911184 0.9513850911511461 0.9913702237782164 1.0718394401310423 1.1664496883233788 1.2080917651480039 1.086343762426262 1.0 16.86995002703265 -6.324802412114392 1.2610430154143113 1.1301899259662114 0.8102585845689847 0.8096433381699045 0.06159374190129568 0.17426622847920037 0.5674890909733636 0.02481437345566045 0.03358603418236964 4.7336657421635304e-07 6.324802412114392 -0.3199313413972267 SVSS(ph)PTSSNTPTPTK ddPTM_PC-9_Lapatinib_30min_R1 4 SVSSPTSSNTPTPTK 15 0 Q5M775;Q5M775-4;Q5M775-2;Q5M775-5;Q5M775-3 Q5M775 SPECC1 Cytospin-B 1 SVSS(0.866)PT(0.133)SSNTPTPTK;SVS(0.003)S(0.662)PT(0.057)S(0.171)S(0.098)NT(0.009)PTPTK;SVS(0.153)S(0.815)PT(0.024)S(0.006)S(0.002)NTPTPTK;SVS(0.388)S(0.577)PT(0.017)S(0.009)S(0.009)NTPTPTK 241.41 1.1860999999999999e-32 43013400.0 84680.0 83456.0 72954.0 69070.0 91543.0 90177.0 85954.0 88387.0 103834.0 81885.0 True False 83472.44767158969 83262.76275952155 66956.00373058385 74149.63821076574 86158.6207204627 86320.33992285408 90404.2775438479 92493.7826926072 92139.12149950641 96038.71314509613 0.8691541664607562 0.8669708290835534 0.6971772271607402 0.7720807139381367 0.897123856608673 0.8988077525824462 0.9413316212105458 0.9630885261120354 0.9593956278891598 1.0 16.551328452092932 -6.7194053551411566 1.570250099612914 0.9621086321086364 0.8011342013718511 0.6668017771133712 0.05063550743812925 0.25426767414053253 1.3016824286270041 0.023804693098696112 0.022371401055086948 1.9080715005865646e-07 6.7194053551411566 -0.1609744307367853 SVSS(ph)YGNIR ddPTM_PC-9_AZD4547_30min_R2 1 SVSSYGNIR 9 0 Q8N122-3;Q8N122 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 1 SVS(0.041)S(0.959)YGNIR 158.47 0.00011567 29506000.0 34986.0 46389.0 76100.0 82567.0 80747.0 61803.0 74634.0 85917.0 66509.0 60014.0 True False 46110.82024599298 61383.3370636624 75090.86427714335 63532.45379743361 69536.6728446762 57938.44863999773 81276.28141478398 72640.50182624979 70024.52995918543 57912.928126839906 0.7962094429934858 1.0599245979968699 1.2966166054094281 1.0970340449421918 1.2007107064657163 1.000440670399223 1.4034220690201342 1.2543054577926678 1.2091346824290925 1.0 15.821597822107988 -4.847923286566662 3.0744532223677274 1.1907727125799155 0.763038078868249 0.48779987017399096 0.11982105655573431 0.2543532237072587 3.856096942492231 0.03000755341165652 0.24655319986850652 1.4193082050254836e-05 4.847923286566662 -0.4277346337116664 SVSS(ph)YGNIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SVSSYGNIR 9 0 Q8N122-3;Q8N122 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 1 S(0.403)VS(0.098)S(0.499)YGNIR;SVS(0.037)S(0.963)YGNIR;SVS(0.019)S(0.981)YGNIR 146.11 0.00045592 63283000.0 129861.0 138975.0 192508.0 203542.0 215871.0 180487.0 190899.0 165328.0 183505.0 150262.0 True False 151843.90242833714 152771.51954622168 197098.1208106558 192138.20163206762 173572.6271929393 171021.9439907953 172815.664730926 160988.3151794959 186188.41346764765 177503.31112666219 0.8554426476021335 0.8606685620484427 1.1103912347303269 1.0824485493398055 0.9778557148665354 0.9634859367144879 0.9735912171666972 0.9069595049109728 1.0489292412961693 1.0 17.437486411175037 -5.188639187288133 11.825009652600906 1.0033913007067201 0.8577622348720414 0.5261542964705366 0.05677055684369901 0.8816265305134544 141.26596540342527 0.015735503111991827 0.04168313023706239 6.476804865108304e-06 5.188639187288133 -0.14562906583467872 SVSS(ph)YGNIR ddPTM_PC-9_Lapatinib_30min_R1 2 SVSSYGNIR 9 0 Q8N122-3;Q8N122 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 1 SVS(0.203)S(0.797)YGNIR;SVS(0.04)S(0.96)YGNIR 169.99 0.0010921 68355000.0 116412.0 98408.0 96469.0 87764.0 83026.0 82867.0 90269.0 81165.0 87287.0 63114.0 True False 114751.94353265357 98180.14232216925 88537.69120110868 94218.45733212153 78142.57391539634 79322.97158241192 94942.68713039081 84936.2222074001 77455.81888714133 74023.17080588137 1.5502165373809706 1.3263433767196655 1.1960807708884864 1.272823851050644 1.055650184458022 1.0715965111847041 1.2826076767147527 1.1474275052353156 1.0463726160861408 1.0 16.17568931480855 -1.5228787453082562 0.5513171089785842 1.110646058363703 20.93149662854024 0.7387338463071861 0.08149271750801197 72.53370090945921 0.6615654429371236 0.04122739100542627 1703.3188750281568 0.02999999999807145 1.5228787453082562 19.82085057017654 SVSSNVASVS(ph)PIPAGSK ddPTM_PC-9_AZD4547_30min_R2 1 SVSSNVASVSPIPAGSK 17 0 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 SVSSNVAS(0.033)VS(0.496)PIPAGS(0.471)K 159.26 2.9051e-05 40997000.0 61487.0 55658.0 72042.0 85985.0 72278.0 60262.0 54278.0 78664.0 61640.0 55586.0 True False 81038.58699094984 73648.36004848822 71086.67600859336 66162.48670500726 62243.44730909507 56493.80761360364 59108.63684958126 66508.28631889018 64898.164559445926 53639.95105906165 1.5107878622357471 1.3730131850306089 1.3252561683048807 1.2334553891027484 1.1603934395943114 1.0532039365844998 1.101951729681822 1.2399020693672804 1.2098848577991455 1.0 15.711020300481596 -5.400102685841331 0.9515930544138822 1.1311702694712367 1.5309270199158058 0.7782317505276324 0.06879858195367343 0.4765568114806394 0.63287644973385 0.027281280530107744 0.1612988434767236 3.980130520718145e-06 5.400102685841331 0.39975675044456915 SVSSNVASVS(ph)PIPAGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVSSNVASVSPIPAGSK 17 0 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 SVSSNVAS(0.052)VS(0.923)PIPAGS(0.025)K;SVS(0.001)S(0.001)NVAS(0.027)VS(0.596)PIPAGS(0.375)K 105.2 0.00073784 35158300.0 161832.0 164069.0 151462.0 163604.0 173329.0 125836.0 146980.0 130565.0 112089.0 106739.0 True False 189226.96127230316 180356.68602575333 155073.42850283376 154437.79829132423 139366.42670263734 119236.93863838247 133056.99035695073 127137.8070950524 113728.08957344558 126089.93575454097 1.500730095070164 1.4303812984475885 1.2298636491076884 1.2248225630947103 1.1052938195950999 0.9456499277666441 1.0552546447162325 1.0083105073711143 0.9019600881932388 1.0 16.944093601677388 -5.382597566232765 0.5947454317891414 0.9632323984804823 1.67107484385539 0.9352294133700743 0.04891981328413828 0.4651512114771841 0.20249558156475608 0.028467580778102596 0.20638177804138305 4.143834804446278e-06 5.382597566232765 0.7078424453749077 SVSSNVASVS(ph)PIPAGSK ddPTM_PC-9_Lapatinib_30min_R1 4 SVSSNVASVSPIPAGSK 17 0 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 S(0.007)VS(0.298)S(0.238)NVAS(0.083)VS(0.366)PIPAGS(0.009)K;SVS(0.002)S(0.001)NVAS(0.343)VS(0.655)PIPAGSK;SVSSNVAS(0.178)VS(0.818)PIPAGS(0.003)K;SVS(0.002)S(0.001)NVAS(0.251)VS(0.701)PIPAGS(0.045)K 106.58 0.00064706 76836100.0 196452.0 181323.0 237492.0 180047.0 181038.0 171670.0 147976.0 137180.0 184896.0 117001.0 True False 193650.5584551153 180903.15773395234 217966.32450563123 193288.25699918473 170389.70077440244 164328.07428231544 155637.4732278711 143553.8836002113 164071.06543880393 137224.46695596728 1.4111955597339219 1.3183010416939767 1.5883925756153419 1.408555349398495 1.2416860094568796 1.1975129357583527 1.134181656379195 1.046124548957257 1.1956400274555354 1.0 17.066178209657636 -6.575545544871979 1.5516600434171062 1.102211310574908 1.4380411268750746 0.7753846241403786 0.08117785912634166 0.18426449971700432 0.9112493396401672 0.0336375321780501 0.03551549563123302 2.657384852484815e-07 6.575545544871979 0.3358298163001665 SVSSNVASVS(ph)PIPAGSKK ddPTM_PC-9_Lapatinib_30min_R1 1 SVSSNVASVSPIPAGSKK 18 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 SVSS(0.001)NVAS(0.083)VS(0.916)PIPAGSKK 106.58 0.00014472 25054000.0 181140.0 112110.0 160470.0 114240.0 112350.0 105880.0 66533.0 75972.0 101650.0 79245.0 True False 178556.91038299224 111850.41618301783 147276.77603211324 122641.59069346805 105741.79388859871 101351.75921833506 69977.75319153079 79501.93646942166 90201.10657804618 92942.39266267465 1.921156807648014 1.2034380972842824 1.5846028040900553 1.3195441518122277 1.137713274419115 1.0904793422543078 0.7529153402098031 0.8553893889730834 0.9705055356754403 1.0 16.504049164898873 -6.157611746697168 0.793211196934039 0.8738286813036071 1.6431505003548896 0.7231644865941713 0.17504126839141732 0.37764526046912833 0.4991069525254275 0.09076446246127022 0.1784687670312998 6.95645937602712e-07 6.157611746697168 0.7693218190512825 SVSSNVASVSPIPAGS(ph)K ddPTM_PC-9_AZD4547_30min_R2 2 SVSSNVASVSPIPAGSK 17 0 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 SVSSNVAS(0.01)VS(0.075)PIPAGS(0.915)K;SVSSNVASVS(0.051)PIPAGS(0.949)K 153.36 1.7607e-08 36090000.0 84370.0 74386.0 86556.0 114871.0 84675.0 79950.0 67572.0 110189.0 76962.0 79836.0 True False 111197.90499498165 98429.81980248757 85408.21088531426 88389.26568925848 72919.33784689158 74950.7138612659 73585.77709569094 93161.82194132265 81030.05419896299 77040.96594018702 1.44336073202033 1.2776296169353123 1.108607736715339 1.1473021477674883 0.9465008253336883 0.9728683038509156 0.9551512782539796 1.2092504397420396 1.0517787934002931 1.0 16.233338171365055 -4.90380574292141 1.0853337831548246 1.0332372135050072 1.5957755860041878 0.7501389591573099 0.07670261458053754 0.7631772996770757 0.8533302586445186 0.026581641320930226 0.472244281075666 1.2479415855242164e-05 4.90380574292141 0.5625383724991806 SVSSNVASVSPIPAGS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVSSNVASVSPIPAGSK 17 0 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 SVSSNVAS(0.001)VS(0.419)PIPAGS(0.58)K;SVSSNVAS(0.01)VS(0.251)PIPAGS(0.738)K 200.71 1.2083e-12 35494700.0 153038.0 156730.0 151635.0 146994.0 170322.0 123616.0 144459.0 118015.0 110538.0 85303.0 True False 178944.31076172052 172289.11860751497 155250.55347893958 138758.40274097817 136948.62676670705 117133.3593464692 130774.79772740997 114917.23129722828 112154.40913264945 100767.75864182337 1.7758091791817447 1.7097643227325576 1.5406768550918555 1.3770118995520348 1.3590520282731278 1.162409097167845 1.2977841274831359 1.1404166654703403 1.1129989457371943 1.0 16.62067458660725 -2.3908956533004933 0.22778008621902876 0.9856039788179459 4.337235838870879 0.9569348888664128 0.05118532595845208 6.076692050132668 0.11168200703134736 0.07602988825199224 6.975692316637335 0.004065409958800756 2.3908956533004933 3.351631860052933 SVSSPTS(ph)SNTPTPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVSSPTSSNTPTPTK 15 0 Q5M775;Q5M775-4;Q5M775-2;Q5M775-5;Q5M775-3 Q5M775 SPECC1 Cytospin-B 1 S(0.001)VS(0.015)S(0.326)PT(0.1)S(0.409)S(0.135)NT(0.015)PTPTK 84.62 0.0060486 11390000.0 44107.0 42736.0 42528.0 51541.0 69345.0 70477.0 73096.0 69441.0 64077.0 51740.0 True False 51573.44394704067 46978.54764761537 43542.02880833813 48653.32486817655 55757.34504724767 66781.06205233229 66171.81771078827 67618.24732882134 65014.00490322577 61120.05242638539 0.8438056235170461 0.7686274108517427 0.71240169273057 0.7960288471083349 0.912259444057305 1.0926211513441546 1.0826531569240285 1.1063185426789768 1.0637099007977842 1.0 15.899358160410902 -6.520848336706892 2.454560370901402 1.0777249761558922 0.7733175140648637 0.914218053802525 0.041635381802231114 0.07560739423288405 0.9157319578866835 0.01494572128465778 0.016044467311425725 3.01405840277665e-07 6.520848336706892 -0.30440746209102854 SVSSPTSSNT(ph)PTPTK ddPTM_PC-9_Lapatinib_30min_R1 2 SVSSPTSSNTPTPTK 15 0 Q5M775;Q5M775-4;Q5M775-2;Q5M775-5;Q5M775-3 Q5M775 SPECC1 Cytospin-B 1 SVSSPTS(0.007)S(0.034)NT(0.924)PT(0.034)PT(0.001)K;SVSSPTS(0.001)S(0.003)NT(0.883)PT(0.109)PT(0.004)K 163.9 3.0718000000000003e-15 0.0 29892.0 23964.1 24516.0 19705.1 20422.5 15325.8 11087.9 14314.9 17568.8 12061.9 True False 29465.734598478557 23908.61259879992 22500.389114496724 21154.278788286614 19221.288702179838 14670.351260184723 11661.977208488637 14980.022513111704 15590.016736334248 14146.783343528517 2.0828575572946577 1.6900387896119844 1.590495066483759 1.4953419639358296 1.3587038293742348 1.0370096794403594 0.824355397640513 1.058899549766863 1.1020184841853777 1.0 13.78818643388652 -5.67366623918334 0.6137509909320584 0.9611248720362943 2.1523473291564046 0.9068499464380542 0.11288331430329906 0.448082954645269 0.2596323856548307 0.07366470911577985 0.33031207087630016 2.119989748368782e-06 5.67366623918334 1.1912224571201104 up SVSSS(ph)SYRR ddPTM_PC-9_AZD4547_30min_R2 3 SVSSSSYRR 9 1 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 1 SVSS(0.082)S(0.535)S(0.383)YRR;SVSS(0.1)S(0.453)S(0.446)YRR;SVSS(0.001)S(0.5)S(0.5)YRR 77.288 0.010671 4891660.0 13680.699999999999 9050.4 14581.499999999998 25155.2 13263.2 14449.400000000001 10963.800000000001 15696.900000000001 12576.8 17245.9 True False 18030.87802376253 11975.764809781855 14388.139782617143 19356.057283965798 11421.833619496809 13545.876733795832 11939.55696030508 13271.304783878128 13241.583971953925 16642.126290243432 1.0834479746937904 0.7196054519068716 0.86456138666922 1.1630759763740903 0.6863205710794865 0.8139510839872187 0.7174297774260212 0.7974524740662813 0.7956665957833104 1.0 14.022552151514951 -6.308071293979724 24.999988752926612 0.788064769725407 0.9340179840535249 0.22738619613701305 0.13662639229795343 653.5964820661726 350400.07818634715 0.04151741716653177 0.04707646413671904 4.919587688769676e-07 6.308071293979724 0.14595321432811792 SVSSS(ph)SYRR ddPTM_PC-9_Lapatinib_30min_R1 2 SVSSSSYRR 9 1 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 1 SVSS(0.09)S(0.455)S(0.455)YRR;SVSS(0.092)S(0.454)S(0.454)YRR 84.31 0.006099800000000001 22445900.0 11655.8 9939.2 12077.2 10344.0 11736.6 11355.8 7575.1 8680.4 9868.6 11591.599999999999 True False 11489.586154588065 9916.186393062635 11084.259235340172 11104.732266572453 11046.276263043408 10870.138905662721 7967.3016127510355 9083.72307335817 8757.094347034983 13595.192615163884 0.8451212483575072 0.7293891799666201 0.8153072596394808 0.8168131618956537 0.812513406446522 0.7995575504784187 0.5860381561541409 0.6681569971451757 0.6441316864659531 1.0 13.73080897099842 -7.068548813839339 24.99686044711338 0.6963378767417193 0.8015509508408051 0.09124264457700482 0.10749158120650187 291.22345895606486 106195.58503076038 0.03833225466591189 0.029692048561074585 8.539868555933556e-08 7.068548813839339 0.10521307409908576 SVSSSS(ph)YRR ddPTM_PC-9_AZD4547_30min_R2 1 SVSSSSYRR 9 1 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 1 SVSS(0.029)S(0.126)S(0.822)Y(0.022)RR 65.278 0.02364 3583800.0 6676.0 5435.3 9067.6 11419.0 8548.7 7365.4 8848.9 8449.0 6854.5 7873.7 True False 8798.829130573633 7192.15443191542 8947.357699335413 8786.525971791336 7361.860566303182 6904.840373655641 9636.434957409248 7143.401188705182 7216.814876260904 7598.044159567758 1.158038693351604 0.9465797093135837 1.1775869567786792 1.1564194399590315 0.9689152118223525 0.9087654965733245 1.2682783562497026 0.9401631576081233 0.9498253398768689 1.0 12.891412381582668 -6.265739606815928 24.864365759394666 1.0112524857590706 1.1028600754864715 0.1711170977619172 0.11101030658007853 727.4276479280385 4206067.349929506 0.03468185736878607 0.040771389260230384 5.42325959363229e-07 6.265739606815928 0.0916075897274009 SVSSSS(ph)YRR ddPTM_PC-9_Lapatinib_30min_R1 1 SVSSSSYRR 9 1 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 1 SVS(0.001)S(0.094)S(0.434)S(0.471)YRR 65.627 0.023209999999999998 7508000.0 5949.5 3325.0 5097.7 4610.6 4707.9 3958.8 4812.2 4696.7 4700.1 4133.4 True False 5864.6590389953235 3317.3011667873907 4678.586783691057 4949.678904510725 4430.990578087525 3789.4913524135304 5061.352169724562 4914.925828146323 4170.725243752822 4847.852682590702 1.209743658270828 0.6842825852980785 0.9650843559030781 1.0210043969128217 0.9140109793352044 0.7816845107571253 1.0440400113436958 1.013835640219945 0.8603242542271269 1.0 12.243130143265637 -10.765273111617715 4.7787813606289395 1.0000147594873874 0.9384109898991516 0.013162337048499229 0.13922580881507063 2.071827980223398e-05 3.2845300960073323e-06 0.12757017550630295 0.030932900208497798 1.716828398200731e-11 10.765273111617715 -0.06160376958823577 SVSSSSYR ddPTM_PC-9_Lapatinib_30min_R1 2 SVSSSSYR 8 0 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 0 ; 107.29 0.017565 26499000.0 50517.0 61331.0 58692.0 60746.0 61487.0 62671.0 54951.0 47551.0 57650.0 50804.0 False True 49796.61831631677 61188.99183766543 53866.570317671765 65213.46348271556 57870.45554809315 59990.70742323643 57796.093902692 49760.39305346 51156.84991858688 59585.40370792519 0.8357184011105987 1.026912432071463 0.9040229144324353 1.0944536652361694 0.9712186533427156 1.0068020637620911 0.969970669091981 0.8351104457959995 0.858546669740575 1.0 15.86267134484747 -10.33653680058304 5.345811807228115 1.0000000071921018 0.9504928997472999 0.034959594894935275 0.08224607844764092 2.2661456903785452e-08 5.007732983377564e-09 0.08166046280113903 0.019805562384888578 4.6074772489850275e-11 10.33653680058304 -0.04950710744480191 SVSSVLSS(ph)LTPAK ddPTM_PC-9_AZD4547_30min_R2 1 SVSSVLSSLTPAK 13 0 H0Y4T7;E7ESY4;Q13330-3;Q13330;F8W9Y9 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 SVSSVLS(0.031)S(0.592)LT(0.377)PAK 176.43 0.00015189 26358000.0 35727.0 37114.0 54334.0 62290.0 67639.0 61831.0 54076.0 59471.0 52068.0 58171.0 True False 47087.44283223547 49110.37469617294 53613.49565879509 47930.0028709066 58248.492384126286 57964.697795571425 58888.659240907065 50281.12345762643 54820.208181071226 56134.45099587436 0.8388332298056357 0.8748704908467412 0.9550907634731379 0.8538429078860904 1.0376603200128796 1.0326046976006158 1.0490644906322346 0.8957266449674886 0.9765875894127882 1.0 15.77659883712269 -6.258853419390415 24.999049081447353 0.9976163539131233 0.8855623857372789 0.5765983575822307 0.04943912777550666 192.73864161383452 1863247.4114322334 0.0159358374376567 0.019642625285540435 5.509936332705283e-07 6.258853419390415 -0.11205396817584445 SVSSVLSS(ph)LTPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVSSVLSSLTPAK 13 0 H0Y4T7;E7ESY4;Q13330-3;Q13330;F8W9Y9 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 SVSSVLS(0.041)S(0.879)LT(0.08)PAK 203.85 1.0282999999999999e-09 22482000.0 68772.0 58633.0 78000.0 81094.0 83692.0 83462.0 81844.0 90756.0 67479.0 69416.0 True False 80413.74129108504 64453.696748002396 79859.81581664729 76550.5660902952 67293.1533880488 79085.1057935461 74091.14382075294 88373.75116393056 68465.75271727426 82000.5713032465 0.9806485493095749 0.7860152157921685 0.9738934076607529 0.9335369848485978 0.8206424945405787 0.9644457902748176 0.9035442393048253 1.0777211641259838 0.83494238673144 1.0 16.323346340664187 SVSSVLSSLT(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 1 SVSSVLSSLTPAK 13 0 H0Y4T7;E7ESY4;Q13330-3;Q13330;F8W9Y9 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 SVSSVLS(0.001)S(0.024)LT(0.975)PAK 167.32 0.0006963999999999999 22700000.0 24548.0 26276.0 33695.0 40243.0 41228.0 36361.0 33006.0 31512.0 29448.0 36458.0 True False 32353.753369880378 34769.20314481436 33248.18228407809 30965.598098152084 35504.203847081735 34087.34092194487 35943.47005890562 26642.544473722042 31004.56116071648 35181.61651695156 0.9196210001974005 0.9882775888953685 0.9450441899978677 0.880164164237079 1.0091692014769913 0.9688963810267379 1.0216548759658892 0.7572859666890197 0.8812716478157719 1.0 15.10253415250743 -7.743148488257913 24.99989713947321 0.8644590104169836 0.9611551336198236 0.22961107809934544 0.06741323172517688 279.54890376073774 382086.94207335863 0.03057253342679033 0.017608946994540124 1.806556346417184e-08 7.743148488257913 0.09669612320284005 SVSSVLSSLT(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVSSVLSSLTPAK 13 0 H0Y4T7;E7ESY4;Q13330-3;Q13330;F8W9Y9 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 SVSSVLS(0.001)S(0.022)LT(0.977)PAK 204.18 2.4223000000000002e-09 19609000.0 69664.0 66269.0 67290.0 74674.0 80100.0 71270.0 82504.0 95502.0 61816.0 55868.0 True False 81456.73927328199 72847.74836343656 68894.4487987461 70490.25787637442 64404.98000266122 67532.47573633549 74688.62384276689 92995.17369273331 62719.94205561755 65996.42614915528 1.2342598535439724 1.1038135337631307 1.0439118118766182 1.0680920466369324 0.9758858738366029 1.0232747389034167 1.131707096895926 1.4090940846184534 0.9503536132982003 1.0 16.010100281043393 -7.510525085908863 24.76863736967576 1.161914380042599 1.0705999357775584 0.0011032774078154617 0.13110633694547302 1325.5295069779306 2657656.025729045 0.05609061396590613 0.03558847519831559 3.0865613532202784e-08 7.510525085908863 -0.09131444426504065 SVSSVLSSLT(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 2 SVSSVLSSLTPAK 13 0 H0Y4T7;E7ESY4;Q13330-3;Q13330;F8W9Y9 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 SVSSVLS(0.028)S(0.174)LT(0.798)PAK;SVSSVLSS(0.008)LT(0.992)PAK 164.15 0.00081323 37881000.0 236690.0 211694.0 225259.0 226994.0 219861.0 200424.0 187587.0 183554.0 221611.0 173424.0 True False 233314.75719637028 211203.83554944023 206739.07454488552 243687.89598978581 206929.20824335728 191852.33273116354 197299.33698975996 192082.5889368211 196650.83551271382 203400.10732704587 1.1470729306018743 1.0383663918615678 1.016415759370623 1.1980716194901582 1.0173505361559962 0.9432263102137172 0.9700060613661501 0.9443583460257108 0.9668177568683386 1.0 17.633960914891595 -6.51238250301615 13.586121268132851 0.9637775534597279 1.0918774717694457 0.617013503697159 0.05004119365725305 0.9143363569912099 1182.279259171813 0.015928628447055497 0.01699111369369125 3.073388748300082e-07 6.51238250301615 0.1280999183097178 SVST(ph)MNLSK ddPTM_PC-9_Lapatinib_30min_R1 2 SVSTMNLSK 9 0 Q14244-5;Q14244-3;Q14244-6;Q14244;Q14244-7;A0A087WZ40 Q14244-5 MAP7 Ensconsin 1 S(0.001)VS(0.492)T(0.507)MNLSK;SVS(0.275)T(0.724)MNLSK 117.14 0.0045878 49164000.0 410440.0 331155.0 376020.0 286945.0 335164.0 320139.0 298211.0 286714.0 301971.0 197719.0 True False 404587.05033452297 330388.23094360175 345105.0870791743 308047.89252045896 315450.3124777774 306447.4012504584 313650.90642237075 300035.7791409175 267959.846084399 231894.46570599327 1.7447033464243062 1.4247352990410884 1.4881988926666099 1.3283969135814417 1.360318416903145 1.3214951047559145 1.3525588265656678 1.2938462253830456 1.155524972399001 1.0 17.823108864089583 -1.5228787452806596 0.10487256610327843 0.8424422458719288 3.132194141767214 0.836997212957231 0.07501777513502284 47.50184992500515 0.35184261884185775 0.8198692633159942 15.681933550498917 0.029999999999977756 1.5228787452806596 2.2897518958952854 SVST(ph)PLTTLDATSDK ddPTM_PC-9_AZD4547_30min_R2 2 SVSTPLTTLDATSDK 15 0 A0A3B3IRW6;Q2KHR3-2;Q2KHR3;H0YCQ7 A0A3B3IRW6 QSER1 Glutamine and serine-rich protein 1 1 SVS(0.016)T(0.984)PLTTLDATSDK;S(0.006)VS(0.37)T(0.624)PLTTLDATSDK 148.18 7.814e-10 3825700.0 34757.0 43373.0 50464.0 64703.0 61710.0 50136.0 47668.0 69942.0 53788.0 65052.0 True False 45809.003009488886 57392.47404475696 49794.814387408165 49786.72300138497 53142.63169213676 47000.987994351824 51910.359654847976 59134.07100726923 56631.12386962161 62774.549280287756 0.7297384614416287 0.9142634188976828 0.793232527486176 0.7931036315225097 0.8465633334116892 0.7487268094031686 0.8269332117872917 0.9420070981829941 0.9021350932646953 1.0 15.937892144568677 -7.7314771231089745 4.69239540625509 0.9431361674493908 0.8086197645870857 0.5991823887847132 0.05279277686967741 0.1362330369875171 7.060701375285761 0.026196024912789908 0.013774666324815839 1.8557645610911835e-08 7.7314771231089745 -0.13451640286230504 SVST(ph)PLTTLDATSDK ddPTM_PC-9_Lapatinib_30min_R1 2 SVSTPLTTLDATSDK 15 0 A0A3B3IRW6;Q2KHR3-2;Q2KHR3;H0YCQ7 A0A3B3IRW6 QSER1 Glutamine and serine-rich protein 1 1 SVS(0.089)T(0.91)PLTTLDATSDK;S(0.008)VS(0.178)T(0.803)PLT(0.008)T(0.002)LDATSDK 192.46 8.7883e-08 5438600.0 38649.0 59927.0 67315.0 41431.0 53694.0 46623.0 48656.0 39710.0 57183.0 48548.0 True False 38097.85817264144 59788.242713403895 61780.620543414414 44477.97394976442 50535.824486465644 44629.04297352131 51175.16960436358 41555.071568482206 50742.44837631489 56939.45711385622 0.6690941590198325 1.0500318363389247 1.085022999426879 0.7811450302525049 0.8875361137605183 0.7837981820634682 0.8987646212016677 0.7298115169132826 0.8911649486725913 1.0 15.797141117398136 -5.794966732800288 24.999987989145353 0.8423571699068246 0.9462484783578269 0.07414686633887047 0.12615188200946104 375.3520060786184 279883.3161440423 0.03449764426957848 0.05117173028292883 1.603368204885567e-06 5.794966732800288 0.10389130845100225 SVST(ph)PSEAGSQDSGDGAVGSR ddPTM_PC-9_AZD4547_30min_R2 3 SVSTPSEAGSQDSGDGAVGSR 21 0 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E9PGG1;E7ETL8;E7ESD3;E7EMU4;Q13409;Q13409-7;Q13409-5;E7ET01;E7ERR6;E7EUM4;E7ERH4 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 1 S(0.014)VS(0.062)T(0.918)PS(0.005)EAGSQDSGDGAVGSR;SVS(0.003)T(0.996)PS(0.002)EAGSQDSGDGAVGSR;SVS(0.09)T(0.618)PS(0.283)EAGS(0.008)QDSGDGAVGSR 230.67 3.3646999999999995e-41 52746900.0 49844.200000000004 53332.3 66384.3 108134.0 91403.0 86098.0 57378.4 86796.1 66224.9 73520.0 True False 65693.61877623391 70570.9230050305 65504.0008072689 83205.37695364613 78713.27118062491 80714.27844937178 62484.96644331061 73383.75712095787 69725.41301318706 70946.08717774638 0.9259653546734287 0.9947119821876019 0.9232926495742744 1.1727972642830276 1.1094800899085364 1.13768470764501 0.8807387261084955 1.0343594698479175 0.9827943412650642 1.0 16.114435498438162 -5.666677190397591 24.351448262339662 1.0466461971605912 0.9526599485019609 0.2327918026053114 0.08088543286698772 21.69302499666519 5560.661716870282 0.023294714059830385 0.04034761684220273 2.1543824848641486e-06 5.666677190397591 -0.09398624865863026 SVST(ph)PSEAGSQDSGDGAVGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 SVSTPSEAGSQDSGDGAVGSR 21 0 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E9PGG1;E7ETL8;E7ESD3;E7EMU4;Q13409;Q13409-7;Q13409-5;E7ET01;E7ERR6;E7EUM4;E7ERH4 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 1 S(0.022)VS(0.147)T(0.781)PS(0.05)EAGSQDSGDGAVGSR;SVS(0.16)T(0.803)PS(0.037)EAGSQDSGDGAVGSR;SVS(0.024)T(0.976)PSEAGSQDSGDGAVGSR;SVS(0.331)T(0.587)PS(0.082)EAGSQDSGDGAVGSR;S(0.008)VS(0.044)T(0.85)PS(0.098)EAGSQDSGDGAVGSR 372.52 0.0 67354300.0 80794.0 100039.0 104113.0 91895.0 110655.0 93712.0 93651.0 84087.4 80961.0 64316.0 True False 94470.82844576167 109970.21078528157 106595.44877075107 86746.42107760994 88972.94709356407 88797.57774945234 84779.69930547538 81880.19484796477 82144.90146183611 75975.98167482407 1.243430178369991 1.4474338910940596 1.403015090044875 1.141761108778866 1.1710667652096527 1.1687585443713577 1.1158750099252561 1.0777115746711985 1.081195657509434 1.0 16.213255790274324 -5.80070930730476 6.031941876924279 1.1152777168948265 1.3732152734096121 0.751696883200349 0.06748853257022751 0.0863660813877997 8.087610935003847 0.019121966068094763 0.029339261527077158 1.582306793508425e-06 5.80070930730476 0.25793755651478567 SVST(ph)PSEAGSQDSGDGAVGSR ddPTM_PC-9_Lapatinib_30min_R1 7 SVSTPSEAGSQDSGDGAVGSR 21 0 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E9PGG1;E7ETL8;E7ESD3;E7EMU4;Q13409;Q13409-7;Q13409-5;E7ET01;E7ERR6;E7EUM4;E7ERH4 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 1 SVS(0.035)T(0.962)PS(0.003)EAGSQDSGDGAVGSR;S(0.036)VS(0.049)T(0.895)PS(0.019)EAGSQDSGDGAVGSR;SVS(0.049)T(0.951)PS(0.001)EAGSQDSGDGAVGSR;SVS(0.027)T(0.917)PS(0.055)EAGSQDSGDGAVGSR;SVS(0.086)T(0.634)PS(0.279)EAGS(0.002)QDSGDGAVGSR;SVS(0.235)T(0.758)PS(0.007)EAGSQDSGDGAVGSR;SVS(0.013)T(0.665)PS(0.294)EAGS(0.014)QDS(0.014)GDGAVGSR 266.99 2.4478e-86 100832100.0 136796.1 124623.2 150419.7 117568.1 122088.1 121194.4 123697.1 101981.29999999999 127892.1 102061.70000000001 True False 134845.3625286677 124334.64263722686 138052.77290283304 126214.45026968452 114907.11799243977 116011.1980299451 130101.53058344134 106719.72349903938 113487.54493448244 119702.92885633327 1.1265001100391476 1.0386934039554918 1.1532948627223911 1.0543973441215155 0.9599357266383232 0.9691592272498281 1.0868700693162523 0.8915381145529342 0.9480765927681645 1.0 16.869098926591356 -6.08856193034711 4.0914298017797055 0.9762165448857753 1.100327365799132 0.5485007667626274 0.05346056448068184 0.18392401591551233 5.561130378259064 0.016220160764358733 0.021805032480606907 8.155264848502956e-07 6.08856193034711 0.12411082091335668 SVSTPS(ph)EAGSQDSGDGAVGSR ddPTM_PC-9_AZD4547_30min_R2 3 SVSTPSEAGSQDSGDGAVGSR 21 0 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E9PGG1;E7ETL8;E7ESD3;E7EMU4;Q13409;Q13409-7;Q13409-5;E7ET01;E7ERR6;E7EUM4;E7ERH4 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 1 S(0.009)VS(0.075)T(0.332)PS(0.583)EAGS(0.001)QDSGDGAVGSR;S(0.002)VS(0.055)T(0.366)PS(0.574)EAGSQDS(0.003)GDGAVGSR;SVS(0.066)T(0.35)PS(0.584)EAGSQDSGDGAVGSR 151.07 3.0398000000000003e-05 54581100.0 27689.8 33069.8 44748.0 58633.0 44426.0 43983.0 34432.0 47965.0 36226.0 39217.2 True False 36494.58041638071 43758.96613481437 44154.612282176175 45116.067720819796 38258.21674857993 41232.736057036396 37496.38129637754 40553.11137604968 38140.83240315523 37844.21776478666 0.9643370261529949 1.156291997017607 1.1667465967089223 1.1921522067447634 1.0109395571700384 1.0895386004094576 0.9908087288110689 1.0715801190052234 1.007837779610405 1.0 15.207785266568271 -6.279436703172018 24.968705772367258 1.0332020867516847 1.125830152302432 0.32145424335225803 0.06462658016336825 968.608529264223 1343801.9514669636 0.02002181540908066 0.022751821209017295 5.254885975650275e-07 6.279436703172018 0.09262806555074743 SVSVAT(ph)GLNMMK ddPTM_PC-9_AZD4547_30min_R2 1 SVSVATGLNMMK 12 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 SVS(0.092)VAT(0.908)GLNMMK 95.618 0.0040313 34292000.0 153370.0 145720.0 211790.0 241050.0 163510.0 173880.0 202360.0 180790.0 152950.0 151460.0 True False 202138.46970582358 192821.1402900878 208981.52621887208 185479.64668537545 140809.45888804542 163007.25611253185 220369.6479767355 152853.05964090538 161034.62474638625 146157.43150083633 1.3830187601830353 1.3192701753860832 1.429838524616357 1.2690401355630974 0.9634095060519704 1.1152854455546388 1.5077553410308424 1.0458110687312587 1.1017888251919972 1.0 17.157163660521107 -1.5228787507701371 0.13339611352757838 0.9585549060684337 2.461940178087997 0.3426420550467678 0.14834539763891436 104.35831435972621 0.9405976901347726 0.793849192762148 29.627947178230176 0.029999999620778085 1.5228787507701371 1.5033852720195633 SVSVAT(ph)GLNMMK ddPTM_PC-9_Lapatinib_30min_R1 1 SVSVATGLNMMK 12 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 SVS(0.261)VAT(0.738)GLNMMK 123.26 0.0013875 12957000.0 87133.0 101530.0 98100.0 82494.0 88623.0 81397.0 102480.0 83032.0 77965.0 59239.0 True False 85890.46744176469 101294.91352298473 90034.59667695104 88560.88395191699 83410.36937952177 77915.84005567452 107785.91296150902 86889.96984321874 69183.76069215311 69478.38221899421 1.2362185862508999 1.4579342564958633 1.2958648978492926 1.2746538005559078 1.2005226189149636 1.1214400446182762 1.5513589913733221 1.2506043904324602 0.9957595223516796 1.0 16.084276541314985 -8.221642771293602 4.636919461153754 0.9933954529564889 1.3044473088794244 0.5194212616718255 0.11635913505885555 0.15541572697370368 7.806870887843716 0.09221180127301849 0.03048652037554768 6.002846370631416e-09 8.221642771293602 0.3110518559229355 SVSVVTGS(ph)EQK ddPTM_PC-9_AZD4547_30min_R2 1 SVSVVTGSEQK 11 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 S(0.154)VS(0.354)VVT(0.088)GS(0.404)EQK 134.75 6.476399999999999e-05 52466000.0 153000.0 105700.0 210570.0 235990.0 198560.0 175920.0 236970.0 276080.0 233330.0 199990.0 True False 201650.81740230205 139865.45792384236 207777.7042160062 181586.1515091548 170993.37139508448 164919.69459004243 258059.87092828163 233418.1796872683 245663.34744736372 192988.41097221867 1.0448856301082783 0.724735009834225 1.076633063971476 0.9409173877041493 0.8860292207893227 0.8545575030087333 1.3371780700626124 1.2094932463114048 1.2729435213740776 1.0 17.558154690143105 -7.255583357262723 24.98197810683758 1.2223614828310247 0.9187085448513778 0.5619253670509576 0.12227620886849344 317.6082606477616 1354930.351287685 0.04508959790723494 0.033968352347019184 5.5515805141623584e-08 7.255583357262723 -0.303652937979647 SVT(ph)PASTLTK ddPTM_PC-9_AZD4547_30min_R2 1 SVTPASTLTK 10 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 SVT(0.986)PAS(0.001)T(0.011)LT(0.001)K 105.36 0.0060438 17705000.0 69335.0 69043.0 105180.0 141250.0 169530.0 163550.0 118160.0 149150.0 116500.0 116480.0 True False 91382.08774240896 91359.79954054723 103785.24447660884 108686.99479074587 145993.68580080924 153323.1926455289 128676.01109374948 126102.29462603573 122657.9521605363 112402.07065375253 0.8129929209569965 0.8127946309990616 0.9233392576575633 0.9669483325227103 1.2988522804934222 1.3640602148498786 1.144783279750493 1.1218858682282276 1.0912428164991406 1.0 16.77830908734782 -5.988299437634032 2.840796700153073 1.183537143889678 0.843713107548726 0.6662792937340936 0.10239171338958022 0.16185877198393903 2.65785657194296 0.03318218400890738 0.04989892135953416 1.027307745093987e-06 5.988299437634032 -0.33982403634095204 SVT(ph)PASTLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVTPASTLTK 10 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 S(0.004)VT(0.995)PAS(0.001)TLTK;S(0.002)VT(0.537)PAS(0.187)T(0.271)LT(0.003)K 121.29 0.0015526 27000000.0 111951.0 122957.0 196664.0 189643.0 227480.0 179475.0 170855.0 116429.0 149145.0 128802.0 True False 130902.0931669609 135163.3583654959 201353.2156123734 179017.91754090137 182906.92697884366 170063.0150523195 154670.37751691943 113372.86211672233 151325.96347038102 152152.78300392866 0.860333216274992 0.8883397049793424 1.3233620288573646 1.176566829778454 1.2021267266213653 1.117712155471572 1.0165464900692993 0.7451251293497207 0.9945658599387808 1.0 17.215161196651117 -7.528926906298074 24.090695817524555 0.8980743867263697 1.1012490125276855 0.23536146415047798 0.14557404246600134 144.68999895219554 576303.0471023765 0.07286801916726245 0.04224089739530094 2.95851035516465e-08 7.528926906298074 0.20317462580131573 SVT(ph)PPEEQQEAEEPK ddPTM_PC-9_AZD4547_30min_R2 1 SVTPPEEQQEAEEPK 15 0 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4;P30305-3 G8JLH2 CDC25B M-phase inducer phosphatase 2 1 S(0.368)VT(0.632)PPEEQQEAEEPK 87.363 0.012681 10959000.0 40330.0 32436.0 39347.0 38749.0 34750.0 43263.0 44327.0 41602.0 32296.0 42842.0 True False 53154.10108388772 42920.3026794489 38825.233071126924 29816.016716082166 29925.562328662298 40557.75777085614 48272.017127222614 35173.36681885581 34003.100626409236 41342.11462008991 1.2857131661586043 1.038173859123115 0.939120638310554 0.721202023410609 0.7238517575518544 0.981027655299165 1.1676233199683783 0.8507878017870802 0.822480923844318 1.0 15.335324563036899 -4.8352571070989425 2.0488161648013548 0.8951145625437315 1.3683567743507175 0.4651649983891749 0.12686414079241626 0.6206399126294316 3.2027582328209068 0.037750968778068814 0.5345180351743627 1.4613118057036634e-05 4.8352571070989425 0.473242211806986 SVTEQGAELSNEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVTEQGAELSNEER 14 0 P63104;E7EX29;E7ESK7;E9PD24;E7EVZ2;E5RIR4;E5RGE1 P63104 YWHAZ 14-3-3 protein zeta/delta 0 96.23 0.019489 0.0 11699.0 8125.5 13665.0 12714.0 11737.0 9353.7 12810.0 14027.0 9357.0 7633.3 False True 13679.409634217456 8932.145940441284 13990.825424801087 12001.675799344146 9437.219104759473 8863.175505752237 11596.544063631356 13658.80611283501 9493.828423295152 9017.156864830453 1.5170424380184793 0.9905723139052026 1.551578356074673 1.3309822574068984 1.046584776801143 0.9829235133217225 1.286053269058817 1.5147575136580296 1.0528627332994347 1.0 13.138456903997211 -14.522878745280336 0.11392029102561435 0.25846906130624286 1.3752274988148527 0.144163171200412 0.21023771998921367 394.06074029287527 2.94492861153214 69.14417686054655 2.4497482118279628 3.0000000000000132e-15 14.522878745280336 1.11675843750861 SVTEQGAELSNEER ddPTM_PC-9_Lapatinib_30min_R1 2 SVTEQGAELSNEER 14 0 P63104;E7EX29;E7ESK7;E9PD24;E7EVZ2;E5RIR4;E5RGE1 P63104 YWHAZ 14-3-3 protein zeta/delta 0 ; 196.02 5.509100000000001e-07 15062600.0 17499.1 17685.3 22531.2 19933.5 21773.3 16059.8 14882.6 16381.599999999999 22490.5 17937.4 False True 17249.55962505807 17644.3507744316 20678.771708947144 21399.476086206672 20492.63730195481 15372.959791222294 15653.148206878937 17142.74893997099 19957.38305453561 21037.855689916887 0.8199295536248741 0.8386953040507955 0.9829315313184772 1.0171890330278814 0.9740839372606119 0.7307284553049915 0.7440467525585911 0.8148524827170118 0.9486415036158304 1.0 14.360700043154166 -6.740193505103625 24.994984042347067 0.8296066226528053 0.9298502186566666 0.12952973738577 0.09659834380817298 419.9070287898364 494003.99181737064 0.033662461093427194 0.033630523020956316 1.8188902497176795e-07 6.740193505103625 0.10024359600386135 SVTPAST(ph)LTK ddPTM_PC-9_Lapatinib_30min_R1 1 SVTPASTLTK 10 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 S(0.012)VT(0.134)PAS(0.057)T(0.765)LT(0.033)K 81.017 0.041229 17310000.0 178640.0 131400.0 131540.0 128450.0 120150.0 109390.0 81117.0 98049.0 120380.0 80287.0 True False 176092.56084143647 131095.75137319215 120725.2889590836 137896.64149663894 113083.01322398857 104711.6447005446 85316.84135147063 102604.71448547266 106821.5367424023 94164.50097429703 1.8700525040694729 1.3921992897193372 1.2820679524658296 1.4644227927706956 1.200909175474264 1.112007642127541 0.9060403917476137 1.0896326473761004 1.1344140906301847 1.0 16.522895661035648 -1.5228787452826567 0.3541842238181959 1.0149367495197743 10.46053222437888 0.8200629720842343 0.11165110312397558 27.239717255595792 0.3821757256725097 0.0997188386511495 172.51201968162192 0.029999999999839804 1.5228787452826567 9.445595474859106 SVTPDSLGHT(ph)PPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVTPDSLGHTPPAR 14 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 SVTPDSLGHT(1)PPAR 98.227 0.0052551 4717800.0 35971.0 44693.0 49471.0 36454.0 45011.0 49624.0 56464.0 30774.0 34003.0 33811.0 True False 42060.17984036553 49129.82567425291 50650.57625981229 34411.600565462584 36191.417664167086 47021.63008194067 51115.321156040656 29966.215107748227 34500.22954764403 39940.666652271284 1.0530665450966807 1.230070246497978 1.2681454894276776 0.861568006990332 0.9061295340724866 1.1772870616135978 1.2797813717296556 0.75026827590631 0.8637870230862088 1.0 15.285570792649292 -6.41196959263061 0.3965876364571593 0.9186588727136491 1.197080595881769 0.1423410391516301 0.16849796951664556 3.7270004283135116 1.083595288681706 0.1871755356798947 0.4315127054925299 3.8728475992996294e-07 6.41196959263061 0.27842172316811986 SVTPDSLGHT(ph)PPARGEEELSNYICMGGK ddPTM_PC-9_AZD4547_30min_R2 1 SVTPDSLGHTPPARGEEELSNYICMGGK 28 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 S(0.027)VT(0.025)PDS(0.021)LGHT(0.85)PPARGEEELS(0.06)NY(0.017)ICMGGK 49.765 0.014266999999999998 7404600.0 11812.0 10235.0 20448.0 38834.0 26224.0 19640.0 15794.0 20183.0 18446.0 20366.0 True False 15567.970295137176 13543.263593666268 20176.84615951416 29881.421279319075 22583.25025918965 18411.907695250327 17199.6354029678 17064.181109200697 19421.017901744646 19652.992538927945 0.7921424823370129 0.6891196629134345 1.026655157963785 1.5204514640775966 1.1490998235743262 0.9368500832013588 0.8751662307355675 0.8682739320945946 0.988196472535986 1.0 14.26246138630089 -10.571861925877792 14.491939605337599 0.9999233305371478 0.9883377142018133 0.0 0.2164153032375047 0.0 0.0 0.23529225605766066 0.057066754389153644 2.68002024129692e-11 10.571861925877792 -0.011585616335334503 SVTSS(ph)PVEKK ddPTM_PC-9_AZD4547_30min_R2 1 SVTSSPVEKK 10 1 G8JLP4;Q9Y4F3-3;Q9Y4F3-4;Q9Y4F3-5;Q9Y4F3;F8VVB8 G8JLP4 KIAA0430 Meiosis arrest female protein 1 1 SVT(0.003)S(0.213)S(0.784)PVEKK 88.155 0.010043999999999999 0.0 9295.2 7629.8 9816.1 12873.0 14043.0 10406.0 8546.3 9647.9 10363.0 10480.0 True False 12250.880247829247 10095.983641128962 9685.9321002742 9905.328735867397 12093.371849824593 9755.311174988537 9306.90414362313 8157.038741686434 10910.767023516188 10113.098389863733 1.2113874280218804 0.9983076651610623 0.9577610863533496 0.9794553908222052 1.195812735486255 0.9646214047285644 0.9202821711841896 0.8065815665219039 1.0788748020539334 1.0 13.303937448686577 -6.9795447113174225 24.944109129547225 0.9363357239335423 1.0562065820598894 0.23096930027378693 0.10196563408737154 344.2797063003847 419828.96483865427 0.03601208083571171 0.03175655515400007 1.0482268713785316e-07 6.9795447113174225 0.11987085812634712 SVTVVEDDEDEDGDDLLHHHHVSGSR ddPTM_PC-9_AZD4547_30min_R2 2 SVTVVEDDEDEDGDDLLHHHHVSGSR 26 0 P02545-2;Q3BDU5;Q5TCI8 P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ; 100.85 6.5583e-10 13993400.0 10630.6 11273.0 57781.0 164249.0 73446.0 62149.0 25686.9 99467.0 33017.0 75014.0 False True 14010.909669783718 14916.776794469943 57014.78618656527 126383.93067175362 63249.290670242706 58262.81320530102 27972.98433788107 84096.66067427369 34762.21121445857 72387.78269248456 0.19355351343339816 0.20606760201288266 0.7876299572370332 1.7459290224243194 0.873756431232827 0.8048708088326344 0.3864323964268252 1.1617521292443838 0.48022207507217446 1.0 16.143458605362206 -5.299553661515449 4.768178047096682 0.9227892773927162 0.19224997512767394 0.3922720421385205 0.35314975064810555 0.19098425178762077 10.71660628784524 0.09649800609445268 0.22179225155431542 5.017025847322835e-06 5.299553661515449 -0.7305393022650423 SVTVVEDDEDEDGDDLLHHHHVSGSR ddPTM_PC-9_Lapatinib_30min_R1 1 SVTVVEDDEDEDGDDLLHHHHVSGSR 26 0 P02545-2;Q3BDU5;Q5TCI8 P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 92.8 4.6687e-08 9428800.0 14345.0 10647.0 32844.0 17545.0 23538.0 39219.0 19083.0 24860.0 38132.0 21092.0 False True 14140.437669449188 10622.347525649733 30143.69310150637 18835.317828404255 22153.54111748852 37541.6947939543 20071.024366163896 26015.08635589192 33837.17261223857 24737.724096676604 0.571614333403811 0.4293987387092249 1.2185313808054006 0.761400594282426 0.8955367531350527 1.5175888714434265 0.8113529073137469 1.0516362076892483 1.3678369311582885 1.0 14.594425156117826 -5.067449723542187 0.8876678520429957 1.1078079724532521 0.26385198997143544 0.4130128278593673 0.2485075443570236 1.5248992260752414 1.260851868056986 0.09089355011080522 1.147542442729272 8.561508189869302e-06 5.067449723542187 -0.8439559824818167 SVVS(ph)DLEADDVK ddPTM_PC-9_AZD4547_30min_R2 4 SVVSDLEADDVK 12 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 SVVS(1)DLEADDVK;S(0.021)VVS(0.979)DLEADDVK;S(0.042)VVS(0.958)DLEADDVK;SVVS(1)DLEADDVK 159.12 6.697e-05 24360400.0 92932.9 106565.0 88459.0 79491.0 80051.2 99158.0 101889.0 113699.0 111219.0 96390.0 True False 122483.62907559719 141010.0522578451 87285.9758619161 61165.578073707395 68937.47266429377 92957.63458480831 110956.92361485289 96129.43209309879 117097.80928191134 93015.41543883273 1.316809998619453 1.515985835171309 0.9384033329326543 0.6575853882406202 0.7411402974341098 0.9993788034622884 1.1928874702260353 1.0334785007364058 1.258907555585937 1.0 16.505182213341698 -5.266962183087177 24.90411323973259 0.9674933629968187 1.416397929174667 0.4975273134959165 0.17610013271249167 344.5360800538418 1553632.0181315932 0.051570814783387445 0.11243197241915935 5.408014120759096e-06 5.266962183087177 0.44890456617784824 SVVS(ph)DLEADDVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SVVSDLEADDVK 12 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 S(0.336)VVS(0.664)DLEADDVK;SVVS(1)DLEADDVK;S(0.003)VVS(0.997)DLEADDVK;SVVS(1)DLEADDVK 185.2 0.00044248 24242200.0 113231.0 180301.0 123696.0 123172.0 127591.0 86781.1 142160.0 91768.0 87135.0 93121.9 True False 132398.77188580862 198200.0917122022 126645.3817596924 116271.07216901188 102590.45946965735 82230.14634660451 128693.57565072861 89359.1872362333 88409.18453177548 110004.16331744507 1.2035796454697645 1.801750822287019 1.1512780783962226 1.0569697424404025 0.9326052430725409 0.7475184926347601 1.1698973181528638 0.8123255024299814 0.8036894410682278 1.0 16.74719860076646 -5.582113201791718 2.6416610634718123 0.9207370401538675 1.5037156646289134 0.6001820756261836 0.18272663613822174 0.16622846748058542 2.3289163472082226 0.04947322598501793 0.1045327436111337 2.61750065005842e-06 5.582113201791718 0.5829786244750459 SVVS(ph)DLEADDVK ddPTM_PC-9_Lapatinib_30min_R1 1 SVVSDLEADDVK 12 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 S(0.002)VVS(0.998)DLEADDVK 185.2 0.00044248 5518600.0 12034.0 23301.0 24193.0 21576.0 24092.0 21615.0 24940.0 28482.0 21647.0 20180.0 True False 11862.39295323468 23247.047966109174 22203.944927680655 23162.77101542606 22674.955926694416 20690.576837025994 26231.271167642786 29805.377698652974 19208.8869069844 23668.086111840217 0.5011978111445348 0.9822107227537754 0.9381385897769271 0.9786499384011719 0.9580392694004533 0.8741972941646223 1.1082970986200826 1.2593066274058597 0.8115944321064028 1.0 14.530655428731713 -4.7607089876168125 6.21944956392334 0.9962725250633877 0.48473755356288434 0.6126016076166265 0.11658200947342585 0.088125008594893 14.299919864441026 0.029588815776981848 0.1914822266330957 1.734966175814454e-05 4.7607089876168125 -0.5115349715005033 SVVS(ph)DLEADDVKGSVPLS(ph)SSPPATHFPDETEITNPVPK ddPTM_PC-9_Lapatinib_30min_R1 1 SVVSDLEADDVKGSVPLSSSPPATHFPDETEITNPVPK 38 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 2 S(0.337)VVS(0.376)DLEADDVKGS(0.304)VPLS(0.323)S(0.323)S(0.323)PPAT(0.012)HFPDET(0.001)EIT(0.001)NPVPK 45.336000000000006 0.002859 5304200.0 6890.1 7165.5 4910.4 4744.4 4545.5 4695.8 4125.2 4897.9 6691.5 4311.5 True False 6791.845910510413 7148.908724997008 4506.685866692144 5093.319002854439 4278.14262679684 4494.971580444443 4338.782671241381 5125.474314663031 5937.832805381166 5056.7370302873705 1.3431281614666915 1.4137394691831031 0.8912240916819107 1.007234303929186 0.8460282987177042 0.8889075214949426 0.858020230289652 1.0135932092105953 1.1742419607380143 1.0 12.303991039404744 -5.25937547412536 24.999258757697202 0.9518404379879044 1.3784338552736772 0.7590724992810597 0.09422844640580115 82.10026105007896 994429.8698466443 0.02550654038932206 0.06099414576124135 5.503316952800528e-06 5.25937547412536 0.4265934172857728 SVVS(ph)DLEADDVKGSVPLSSSPPAT(ph)HFPDETEITNPVPK ddPTM_PC-9_AZD4547_30min_R2 1 SVVSDLEADDVKGSVPLSSSPPATHFPDETEITNPVPK 38 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 2 S(0.133)VVS(0.837)DLEADDVKGS(0.152)VPLS(0.152)S(0.152)S(0.152)PPAT(0.411)HFPDET(0.008)EIT(0.004)NPVPK 49.504 0.004476 6282600.0 7701.9 5272.0 9718.6 12283.0 9933.0 7589.5 6736.9 10625.0 8634.2 8065.1 True False 10150.94399052802 6976.070900420964 9589.725013979565 9451.344120458269 8553.974406060514 7114.927365229244 7336.471048895387 8983.150388210744 9090.58618493134 7782.743303825388 1.3042886800003555 0.89635114869998 1.2321779916942663 1.2143975140247434 1.099095019857079 0.9141927322377577 0.9426587467287212 1.1542395833350088 1.1680439441531008 1.0 12.926063058539077 -6.526968372345199 24.98614391021977 1.0359772792360293 1.148979239128203 0.18234420294652365 0.12466167141017048 236.192674351049 1443035.516547269 0.042053186529396984 0.04222572551210227 2.971882452286173e-07 6.526968372345199 0.11300195989217365 SVVS(ph)FDK ddPTM_PC-9_AZD4547_30min_R2 3 SVVSFDK 7 0 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 1 S(0.002)VVS(0.998)FDK;S(0.005)VVS(0.995)FDK;S(0.359)VVS(0.641)FDK 99.68799999999999 0.011761 51032800.0 232675.0 309670.0 320226.0 254198.0 243436.0 341995.0 330831.0 326425.0 291021.0 235048.0 True False 306660.81005934946 409764.7715730953 315979.5940080487 195596.57841995044 209639.11341122998 320609.998586412 360274.31809543096 275983.51675027655 306403.77592885355 226819.0410630431 1.3520064656922466 1.8065713074732708 1.3930911290654118 0.8623463775494291 0.9242571189292786 1.4135056610935066 1.5883777499760026 1.2167563863104793 1.3508732533777457 1.0 17.791182231534172 -5.522089284227791 24.998191200215963 1.2102570700435258 1.5844245156890948 0.3028678157216519 0.23548112345598493 35.07873708379211 1110762.4449022561 0.06839759834058667 0.12034694108208915 3.0054583633601005e-06 5.522089284227791 0.37416744564556903 SVVS(ph)FDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SVVSFDK 7 0 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 1 S(0.042)VVS(0.958)FDK;S(0.001)VVS(0.999)FDK;S(0.278)VVS(0.722)FDK 105.4 0.010208 58324000.0 232186.0 446746.0 330578.0 304443.0 278282.0 194605.0 301930.0 189267.0 184696.0 171698.0 True False 271490.50391746353 491095.99043854274 338460.2332440463 287386.04572752345 223754.63976405177 184399.57121747665 273329.00461609755 184298.94179496265 187396.82958949724 202825.48823937975 1.338542341370053 2.4212735524587465 1.668726333075984 1.4169128753105389 1.1031879755663199 0.9091538386923227 1.3476067874344657 0.9086577007395067 0.9239313619614059 1.0 17.629879435683293 -5.925485678826459 1.9649021002229952 1.0335033569941883 1.9004733846571749 0.6193456155172243 0.2749897191207187 0.2000200461174146 1.56683022345365 0.08381453186011092 0.1427807925016271 1.1871738483113958e-06 5.925485678826459 0.8669700276629866 SVVS(ph)FDK ddPTM_PC-9_Lapatinib_30min_R1 1 SVVSFDK 7 0 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 1 SVVS(1)FDK 89.88600000000001 0.016299 9484700.0 46615.0 75016.0 56438.0 60533.0 69479.0 61712.0 65930.0 76097.0 55263.0 44255.0 True False 45950.26155185596 74842.30506096945 51797.88549698015 64984.798752168375 65392.38182096966 59072.72161769827 69343.53280203247 79632.74442575658 49038.6989948112 51904.41778391919 0.885286137745525 1.4419255288160997 0.997947529488096 1.2520090105374748 1.2598615804381348 1.1381058518683536 1.3359851774219533 1.5342190092040309 0.9447885380192853 1.0 15.663569716662607 SVVS(ph)FDKVK ddPTM_PC-9_AZD4547_30min_R2 1 SVVSFDKVK 9 1 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 1 S(0.004)VVS(0.996)FDKVK 73.9 0.013375 120450000.0 477770.0 644120.0 692440.0 572450.0 564470.0 699250.0 753240.0 616770.0 633530.0 513830.0 True False 629690.9217666506 852319.1935468809 683257.7931677407 440480.49676433613 486103.0839614388 655525.786960478 820276.9007807685 521462.3684646343 667017.1024228706 495840.96809767873 1.269945329815111 1.7189366115043914 1.3779776927047738 0.8883503484076031 0.9803608722094911 1.3220484573419558 1.6543144950845956 1.0516726168578878 1.345223862767771 1.0 18.919517951245837 -5.529074637686758 24.991854249746694 1.1923321524995156 1.5079450591138597 0.23609552625037733 0.23428715473474795 216.83010986219153 874606.8242738569 0.06613964021087905 0.11494772660487752 2.957504147319608e-06 5.529074637686758 0.31561290661434405 SVVS(ph)FDKVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVVSFDKVK 9 1 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 1 SVVS(1)FDKVK 67.08 0.022042 99369000.0 335870.0 443090.0 367180.0 468750.0 421790.0 292810.0 422240.0 298790.0 327650.0 266320.0 True False 392726.15726511733 487077.04692020477 375934.96373790404 442487.4572080042 339143.27734485036 277454.5281374544 382242.37044712726 290947.0790941734 332441.26139709994 314601.7078120398 1.24832811619622 1.5482339568582733 1.1949552542242017 1.406500493227997 1.0780083798765423 0.881923146784762 1.2150041177637207 0.9248108699651465 1.056705202616759 1.0 18.263166976866422 -6.340528484834264 4.881275409513922 1.0199974404767547 1.352483791732534 0.6338948215672477 0.12085629863775024 0.1365179406645423 5.859796233420775 0.03592872515893443 0.04116084926371333 4.5653230583479525e-07 6.340528484834264 0.3324863512557794 SVVSDLEADDVKGSVPLS(ph)SSPPATHFPDETEITNPVPK ddPTM_PC-9_AZD4547_30min_R2 1 SVVSDLEADDVKGSVPLSSSPPATHFPDETEITNPVPK 38 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 SVVS(0.001)DLEADDVKGS(0.014)VPLS(0.294)S(0.294)S(0.294)PPAT(0.057)HFPDET(0.033)EIT(0.013)NPVPK 60.527 4.117600000000001e-05 72209000.0 30455.0 25509.0 38128.0 53434.0 37076.0 36020.0 31930.0 34694.0 30896.0 42203.0 True False 40139.05649664768 33754.285394316845 37622.397807607354 41115.61684707052 31928.637378344847 33767.663705851155 34771.70814339379 29332.83948880784 32529.099484565897 40725.48581559348 0.9856004340475846 0.8288246221827165 0.9238047638759419 1.0095795304503812 0.7839964763813724 0.8291531219235149 0.8538070804321742 0.7202575709379634 0.7987406124965304 1.0 15.313644288357137 -6.27753610226461 24.71440261634541 0.8180541153617841 0.9282898225148108 0.2816182141896051 0.08087573138259398 863.726442208327 1326135.4039362783 0.024383677126415575 0.027739779086712713 5.277933302708855e-07 6.27753610226461 0.11023570715302677 SVVSDLEADDVKGSVPLS(ph)SSPPATHFPDETEITNPVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVVSDLEADDVKGSVPLSSSPPATHFPDETEITNPVPK 38 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 SVVS(0.001)DLEADDVKGS(0.082)VPLS(0.264)S(0.264)S(0.264)PPAT(0.082)HFPDET(0.036)EIT(0.007)NPVPK 42.669 0.009351700000000001 3107700.0 5477.1 7311.6 8138.0 8857.3 13019.0 11184.0 12159.0 15624.0 10292.0 9369.5 True False 6404.264852343999 8037.447327318991 8332.040783536868 8361.05419675404 10468.020407673486 10597.491351693223 11007.211496463215 15213.88655499637 10442.501029448944 11068.116181078814 0.5786228430897961 0.7261802456554605 0.7527966500551081 0.7554180006754395 0.9457815798472368 0.9574792293750823 0.9944972853899278 1.3745687437763656 0.9434759139320047 1.0 13.43412207253718 -6.389906298962021 0.8395946559169488 1.1140757694916947 0.6461955962682427 0.6757704261225207 0.11772114994279195 0.35358978836252125 0.5456344170062849 0.06420487991530167 0.09203903795588345 4.0746818146086396e-07 6.389906298962021 -0.467880173223452 SVVSDLEADDVKGSVPLS(ph)SSPPATHFPDETEITNPVPK ddPTM_PC-9_Lapatinib_30min_R1 3 SVVSDLEADDVKGSVPLSSSPPATHFPDETEITNPVPK 38 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 SVVSDLEADDVKGS(0.002)VPLS(0.314)S(0.314)S(0.314)PPAT(0.054)HFPDET(0.002)EIT(0.001)NPVPK;S(0.064)VVS(0.058)DLEADDVKGS(0.1)VPLS(0.338)S(0.338)S(0.05)PPAT(0.05)HFPDET(0.002)EIT(0.001)NPVPK;SVVSDLEADDVKGS(0.001)VPLS(0.314)S(0.314)S(0.314)PPAT(0.055)HFPDET(0.001)EITNPVPK 98.94 3.0372e-20 108617800.0 453438.7 282955.4 350208.2 282218.0 245389.7 295845.3 222592.1 202451.0 357417.4 213577.6 True False 446972.580987527 282300.2341560277 321415.43363874627 302973.2531716495 230956.36030071235 283192.68616807787 234116.82978648998 211857.61254371147 317161.28863992286 250494.20358573605 1.7843629696387076 1.1269731199963895 1.2831252341882482 1.2095020516830106 0.9220028128182354 1.1305358851193943 0.9346197494201074 0.8457585425572511 1.2661422264462452 1.0 17.934417694404736 -1.522878745351494 0.7582170699494085 1.0273275012762109 131.94201387424255 0.6852248387188207 0.14320592243109762 224.1991778703224 0.9352945760285498 0.052076639419515396 50183.49163128472 0.029999999995084684 1.522878745351494 130.91468637296634 SVVSDLEADDVKGSVPLSS(ph)SPPATHFPDETEITNPVPK ddPTM_PC-9_AZD4547_30min_R2 1 SVVSDLEADDVKGSVPLSSSPPATHFPDETEITNPVPK 38 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 SVVSDLEADDVKGSVPLS(0.077)S(0.423)S(0.423)PPAT(0.077)HFPDET(0.001)EITNPVPK 96.686 4.4531e-20 101500000.0 178910.0 133880.0 224630.0 296950.0 260850.0 232230.0 189930.0 203640.0 178860.0 243340.0 True False 235799.6584408226 177154.09183390703 221651.25942936563 228492.7653317661 224635.48009875006 217708.6213883903 206833.40205683652 172172.11718166902 188314.17445007313 234820.74066693135 1.0041687875232441 0.7544226771909454 0.9439168737814124 0.9730518892104986 0.9566253792605653 0.9271268831282123 0.8808140263479028 0.7332066013107298 0.8019486435279458 1.0 17.841200315320165 -7.529357123061775 24.905981245859184 0.8219486172858821 0.9214123058534015 0.13006824129752304 0.08897040499763664 259.62465733318214 998102.5072744692 0.040727893003709104 0.023591828891516013 2.9555810742585446e-08 7.529357123061775 0.09946368856751941 SVVSDLEADDVKGSVPLSS(ph)SPPATHFPDETEITNPVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVVSDLEADDVKGSVPLSSSPPATHFPDETEITNPVPK 38 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 SVVS(0.001)DLEADDVKGS(0.001)VPLS(0.073)S(0.304)S(0.304)PPAT(0.304)HFPDET(0.01)EIT(0.004)NPVPK 73.758 5.5945e-08 93661000.0 38296.0 34553.0 37928.0 52988.0 51600.0 61915.0 47898.0 67101.0 55040.0 50709.0 True False 44778.756419522324 37983.19348717835 38832.347362741 50019.254149413864 41489.35041369934 58668.0684048718 43360.754688510126 65339.66984938638 55844.85587455008 59902.14028777684 0.7475318278178371 0.6340874183243316 0.6482631033913963 0.835016143148067 0.6926188315539259 0.9793985343933219 0.7238598567630475 1.0907735439082313 0.9322681227459471 1.0 15.870319930600209 -6.959988334579675 0.6336689933742593 1.0114179088865218 0.6681441583179535 0.5656450876455001 0.10168081107654096 0.5412911402107562 0.46210393384015985 0.0799623118678848 0.0720821213861656 1.0965076486261316e-07 6.959988334579675 -0.34327375056856835 SVVSDLEADDVKGSVPLSSSPPAT(ph)HFPDETEITNPVPK ddPTM_PC-9_AZD4547_30min_R2 1 SVVSDLEADDVKGSVPLSSSPPATHFPDETEITNPVPK 38 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 SVVS(0.001)DLEADDVKGS(0.011)VPLS(0.136)S(0.136)S(0.136)PPAT(0.563)HFPDET(0.013)EIT(0.004)NPVPK 57.417 0.00011144 17254000.0 59646.0 45243.0 58622.0 94830.0 93620.0 75442.0 58448.0 76040.0 61590.0 84792.0 True False 78612.18728612867 59866.91497491382 57844.63397706564 72968.40860889504 80622.47899883069 70724.59981390391 63649.7587712208 64289.76522536896 64845.52166152294 81823.45788867635 0.9607536678917099 0.7316595572918079 0.7069443833058885 0.8917785986039736 0.9853223156190779 0.8643560372396775 0.7778913335319867 0.785713130247287 0.7925052709181213 1.0 16.320226886873577 -11.794002315832829 2.232138006156034 1.6833402486135685 0.8304246543059995 0.24519444342057728 0.08780276664635549 8024580.108642369 1292306.720978069 27647268.65140936 0.02414962378780543 1.606932684178731e-12 11.794002315832829 -0.8529155943075689 SVVSDLEADDVKGSVPLSSSPPATHFPDET(ph)EITNPVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SVVSDLEADDVKGSVPLSSSPPATHFPDETEITNPVPK 38 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 SVVSDLEADDVKGS(0.002)VPLS(0.093)S(0.093)S(0.093)PPAT(0.115)HFPDET(0.463)EIT(0.143)NPVPK 68.543 1.7341999999999998e-06 85595000.0 117650.0 80681.0 99926.0 156060.0 141220.0 170130.0 135920.0 189370.0 165880.0 120690.0 True False 137565.82130658012 88690.47647784643 102308.61481146516 147316.46415334634 113548.9547562523 161208.08330325168 123044.6736244165 184399.2381541005 168305.68118587194 142570.14161848545 0.9648992400856501 0.6220831056981074 0.7176019722645767 1.0332911399328055 0.79644274367144 1.130728225932755 0.8630465834401801 1.293393105041228 1.1805114259916654 1.0 17.121312345072944 -6.709656576895395 0.8242217693848669 1.1442888732240128 0.7701902885749466 0.41398608498558553 0.15405989456878566 0.5631847797134016 0.8403011540598051 0.09752876805803316 0.09790187314367944 1.951387070452447e-07 6.709656576895395 -0.3740985846490662 SVWGSLAVQNS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 SVWGSLAVQNSPK 13 0 P18615;P18615-3;P18615-4 P18615 NELFE Negative elongation factor E 1 SVWGSLAVQNS(1)PK;SVWGSLAVQNS(1)PK 204.17 9.918799999999999e-10 46113000.0 210326.0 190423.0 208984.0 255770.0 236481.0 215798.0 242610.0 229602.0 196445.0 217266.0 True False 277205.2929474285 251973.51082527742 206212.73561227997 196806.17810710828 203649.6951091911 202304.1169460094 264201.8200021544 194122.286629079 206828.6816495841 209659.58347062368 1.3221684807280414 1.2018220519863931 0.9835597886760723 0.9386939287451349 0.9713350171647429 0.9649170984561987 1.2601466416591105 0.9258927420137621 0.9864976273720575 1.0 17.67768925124428 -5.083113065637445 3.0707026502417745 1.0054742137202723 1.3111324714004198 0.5836489919992873 0.08967622775525233 0.19010603575606444 3.314578508193908 0.024445323838117785 0.09703047796591038 8.258229241631023e-06 5.083113065637445 0.3056582576801474 SVWGSLAVQNS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SVWGSLAVQNSPK 13 0 P18615;P18615-3;P18615-4 P18615 NELFE Negative elongation factor E 1 SVWGS(0.004)LAVQNS(0.996)PK;SVWGSLAVQNS(1)PK 160.63 0.00029129 42607000.0 108292.0 103560.0 85933.0 111581.0 113172.0 92904.0 103652.0 101300.0 79858.0 74524.0 True False 126623.69673550516 113840.75239580331 87981.9686227172 105329.47832048289 90996.7590119998 88031.95069185502 93833.33218450578 98640.98233622227 81025.77217350696 88034.61126834073 1.4383399314337855 1.2931363103177929 0.9994020233080481 1.1964553123251171 1.0336475359064183 0.9999697780628849 1.065868649075871 1.1204795581541442 0.920385414397186 1.0 16.42578321793686 -5.067725963847972 2.871117944185348 1.0502346047416986 1.4335310375427737 0.7661137120539188 0.07318394497344602 0.1278236069150048 1.9431590589953447 0.01890242678983521 0.08241172691797317 8.556064230209165e-06 5.067725963847972 0.38329643280107506 SVWGSLAVQNS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 SVWGSLAVQNSPK 13 0 P18615;P18615-3;P18615-4 P18615 NELFE Negative elongation factor E 1 SVWGS(0.005)LAVQNS(0.995)PK 164.7 0.00026868 21490000.0 119100.0 119120.0 92965.0 96966.0 110130.0 89684.0 91839.0 76380.0 82231.0 67105.0 True False 117401.6121597348 118844.18495871112 85321.77655527751 104097.20310909358 103652.3699239106 85848.42438361511 96593.9740483217 79928.89363889882 72969.27884918149 78704.00983820797 1.4916852699256058 1.5100143589001298 1.0840842382830773 1.322641671283159 1.3169896951500824 1.0907757376033818 1.2273068963943536 1.015563168931403 0.9271354661494963 1.0 16.26414952006401 -1.5228787452814034 0.19003734596672822 0.9207223018941376 3.6376204375969574 0.6784826166105999 0.11118344147794453 32.63953679322019 0.3815394434823774 0.23203858527265328 26.004863844149902 0.029999999999926374 1.5228787452814034 2.7168981357028197 SWAS(ph)PVYTEADGTFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SWASPVYTEADGTFSR 16 0 E9PMS6;E9PJ10;E9PK58;E9PLU6;Q8WWI1-3;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.014)WAS(0.985)PVYTEADGTFSR 97.823 0.0021352 9197800.0 18656.0 18587.0 18874.0 17005.0 23299.0 20799.0 19101.0 18889.0 17502.0 17392.0 True False 21814.09232720411 20432.194522796388 19324.0277400436 16052.264980953856 18733.728203270948 19708.263825453105 17291.615000735575 18393.18376454984 17757.933639469033 20545.031925003743 1.061769697259798 0.994507801077202 0.9405693702780692 0.7813210044914998 0.9118373858777801 0.9592715113510107 0.8416445914445775 0.8952618731229589 0.8643419832245307 1.0 14.326501951866106 -5.198337502341537 2.3973046068157626 0.8896303341977809 1.0506373505066076 0.461265160398478 0.05821573811566044 0.2678460532495942 2.8470615087840314 0.015514022461157186 0.060156099493111875 6.333773048005685e-06 5.198337502341537 0.16100701630882663 SWCPDCVQAEPVVR ddPTM_PC-9_Lapatinib_30min_R1 2 SWCPDCVQAEPVVR 14 0 I3L0K2;I3L3M7;Q9BRA2 I3L0K2 TXNDC17 Thioredoxin domain-containing protein 17 0 ; 126.83 0.00014133 8625300.0 40379.0 50917.0 51544.0 48714.0 53988.0 52014.0 40213.0 42757.0 50516.0 39112.0 False True 39803.18805539829 50799.10481483115 47306.25128559385 52296.59006514018 50812.53198449185 49789.48247055607 42295.032376279836 44743.64631210257 44826.35612293727 45872.45708653589 0.8676925236490329 1.107398819274089 1.0312561020298778 1.1400433590571684 1.1076915258460382 1.0853894827702584 0.9220136670789743 0.9753924065522831 0.9771954451529551 1.0 15.48534056474613 -7.252938753964935 24.68748437802034 0.9665997462099041 1.06385478631337 0.25611771172637265 0.07274721383045595 693.6154729717719 2014398.079695693 0.02800961580992025 0.021317546481989542 5.585489581070098e-08 7.252938753964935 0.09725504010346597 SWDS(ph)SSPVDRPEPEAASPTTR ddPTM_PC-9_Lapatinib_30min_R1 1 SWDSSSPVDRPEPEAASPTTR 21 1 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 S(0.111)WDS(0.37)S(0.37)S(0.148)PVDRPEPEAASPTTR 50.891000000000005 0.018662 8476100.0 3080.4 4055.3 4925.6 3749.0 5568.9 3679.7 2913.1 1570.1 3981.4 4046.4 True False 3036.4729311238243 4045.9102020068917 4520.636181365845 4024.7139662973827 5241.348250878652 3522.327808799654 3063.9260640922303 1643.0525779318532 3532.97280599934 4745.814848510918 0.6398211957376657 0.8525217125308558 0.9525521592533838 0.8480554119299886 1.1044148198329349 0.7421966345578875 0.6456058994913362 0.3462108468996403 0.7444396628974836 1.0 12.21244010151387 -6.994439236239095 24.971556975268204 0.6387701609559235 0.8845918517263062 0.1870489455973654 0.18506959226723807 192.4037730254977 864015.42776352 0.06435147200099219 0.05658301696290478 1.0128864556230638e-07 6.994439236239095 0.24582169077038263 SWDSSSPVDRPEPEAAS(ph)PTTR ddPTM_PC-9_Lapatinib_30min_R1 1 SWDSSSPVDRPEPEAASPTTR 21 1 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 SWDSSSPVDRPEPEAAS(0.803)PT(0.183)T(0.014)R 90.545 0.00019844 9597600.0 9432.9 10804.0 10385.0 8428.5 10843.0 12156.0 7811.8 8418.5 14309.0 9423.1 True False 9298.385116218004 10778.98400179578 9531.185387259278 9048.360006651772 10205.236058158207 11636.116217020037 8216.256780569045 8809.654243245219 12697.369739550044 11051.870279508508 0.8413404139802766 0.9753085884279068 0.8624047465460428 0.818717536291438 0.923394484377901 1.0528639879708677 0.7434268203276843 0.7971188604682932 1.1488887779557537 1.0 13.432002913387945 -8.263071906635314 24.998156954315615 1.074444394658426 0.880661415468227 0.42889038081138264 0.09113235666585251 146.44075401181436 2242277.6542191864 0.0755210302000444 0.023448906272657766 5.456675068167014e-09 8.263071906635314 -0.19378297919019893 SWEDS(ph)PER ddPTM_PC-9_AZD4547_30min_R2 2 SWEDSPER 8 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IU26;B1AN86 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(0.001)WEDS(0.999)PER;SWEDS(1)PER 115.23 0.0036428000000000003 210793000.0 183029.0 154623.0 213361.0 284100.0 269652.0 235184.0 177956.0 265517.0 193210.0 245669.0 True False 241228.41476030025 204601.86093243377 210531.69373239926 218605.1343012449 232215.47433232924 220477.90730141258 193793.7392535476 224487.4486236752 203422.68615396757 237068.20308582354 1.0175485856826216 0.8630506253863311 0.8880638187322932 0.9221191684745059 0.9795302419711786 0.9300188908994896 0.8174598564084543 0.9469319195978643 0.8580766357786261 1.0 17.854942647899293 SWEDS(ph)PER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SWEDSPER 8 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IU26;B1AN86 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(0.054)WEDS(0.946)PER;S(0.004)WEDS(0.996)PER 80.706 0.018919 66009000.0 197132.0 172169.0 247953.0 195769.0 261358.0 215063.0 226925.0 212139.0 182853.0 135812.0 True False 230502.55406552344 189260.80049471886 253865.13988698888 184800.69762166153 210146.77607410133 203784.71768322613 205429.02120527258 206570.57602985032 185526.87920111004 160433.64051279993 1.4367470147081352 1.179682764099709 1.582368504981564 1.151882466987449 1.3098672784735264 1.2702118896751426 1.28046100897949 1.2875764420079305 1.1564088342576013 1.0 17.291617159323877 -14.456020804341971 0.1164311687255561 3.8796287197233456e-12 1.455418544355228 0.4469511080644051 0.11402654616917694 142.45326275726228 1.097811779736211 33.30067345097179 1.1393022103068486 3.4992840373788633e-15 14.456020804341971 1.4554185443513485 SWEDS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 2 SWEDSPER 8 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IU26;B1AN86 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 S(0.085)WEDS(0.915)PER;S(0.005)WEDS(0.995)PER 136.52 0.0034314999999999997 187093000.0 264438.0 294840.0 312420.0 293140.0 341870.0 278080.0 266390.0 285410.0 420270.0 252457.0 True False 260667.06562800994 294157.31609491503 286734.03357607586 314698.4934863738 321761.87874228024 266187.16663614096 280182.3707437195 298671.1905404314 372934.76696070295 296093.8560721923 0.8803528350296307 0.993459709016032 0.9683890013110087 1.06283358142239 1.0866888054030734 0.8989959135499265 0.9462620213078878 1.008704451022485 1.259515384438695 1.0 18.175695029436774 -8.027863793253667 23.336907566925948 1.1312086030634279 0.9812956727959425 0.34160942374335335 0.08362958816096552 351.66060871030317 294524.09438276646 0.05493234033624552 0.020902544169372306 9.37856098385349e-09 8.027863793253667 -0.1499129302674853 SWLASPGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 SWLASPGSPR 10 0 E7EV07;H0Y451 E7EV07 ARHGEF4 1 SWLAS(0.014)PGS(0.986)PR 84.198 0.012697 4259300.0 10652.0 8752.8 15746.0 16505.0 22873.0 20782.0 12418.0 17230.0 12297.0 19627.0 True False 14039.114424636056 11581.971429667035 15537.197751746371 12700.027249708022 19697.47876671922 19482.498254719554 13523.177943146386 14567.499406011384 12946.994315176942 18939.864703993855 0.7412468169149922 0.6115128914951933 0.8203436505261855 0.6705447714750551 1.0400010282315062 1.0286503393348567 0.7140060477989977 0.7691448504877403 0.6835843084162478 1.0 14.20913840457041 -6.205182301711995 24.999971802910252 0.8608988211895223 0.7116285689180737 0.27230388991438703 0.12861234516849324 467.54705393205376 207771.7689951582 0.04056203999701296 0.05236535055258801 6.234730682459026e-07 6.205182301711995 -0.14927025227144863 SWLVMVS(ph)IIAMGNTLQSFR ddPTM_PC-9_Lapatinib_30min_R1 1 SWLVMVSIIAMGNTLQSFR 19 0 Q9UKR5 Q9UKR5 C14orf1 Probable ergosterol biosynthetic protein 28 1 S(0.061)WLVMVS(0.938)IIAMGNTLQSFR 47.223 0.031569 2899500.0 5135.9 5287.5 3768.8 4405.1 10381.0 19619.0 16339.0 15109.0 18480.0 15303.0 True False 5062.661124191288 5275.2571186130335 3458.9438119887095 4729.065748982821 9770.409989831258 18779.941104122736 17184.953472658995 15811.019298116285 16398.58779697286 17948.10316003423 0.28207221002966604 0.29391724972696076 0.19271918492706686 0.2634855453423749 0.5443700597613806 1.046346844380792 0.957480203864965 0.8809298206689231 0.913666901218189 1.0 14.131543760856092 -6.550334584793394 3.0623299398459505 0.9519530621819838 0.25949461948128905 0.9725804596979983 0.055595413337481005 0.041646978019268595 0.8030347950490831 0.02116660597098881 0.022142167016283475 2.8162124571746276e-07 6.550334584793394 -0.6924584427006948 down SWS(ph)LATFR ddPTM_PC-9_AZD4547_30min_R2 1 SWSLATFR 8 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 SWS(0.993)LAT(0.007)FR 122.94 0.0033068000000000004 3392800.0 11168.0 11784.0 17037.0 24317.0 20908.0 15170.0 13540.0 13269.0 15005.0 11457.0 True False 14719.191691169319 15592.9475513203 16811.078248221955 18711.09134390489 18005.285098350272 14221.417501881238 14745.033769544374 11218.580941286433 15798.133666685364 11055.893917239402 1.3313434265335844 1.4103742011314246 1.5205535051316403 1.6924087264195593 1.6285689093194642 1.2863200034604032 1.3336808294218991 1.014714958850442 1.4289331812465575 1.0 13.432528057605436 -7.065329954658148 2.3019148401318006 1.1872961411185945 1.517640302713788 0.488792110732591 0.1552094028423469 0.27647364384329975 2.8985521440805195 0.06877488870324017 0.05192835407916173 8.603398617479372e-08 7.065329954658148 0.3303441615951934 SWS(ph)LATFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SWSLATFR 8 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 S(0.013)WS(0.987)LATFR 106.88 0.003819 1995800.0 14418.0 14606.0 12657.0 14106.0 18161.0 16403.0 17479.0 15013.0 15869.0 12225.0 True False 16858.682631519558 16055.987152308822 12958.790881939802 13315.686552269044 14602.482419829324 15542.797804168804 15823.262582998635 14618.924657588359 16101.05410380152 14441.295726953247 1.1673940448469937 1.1118107028541708 0.8973426711118104 0.9220562201642776 1.0111615118147077 1.076274463042794 1.0956954889765247 1.012300068774548 1.1149314028484645 1.0 13.817912571565756 -6.75388050593029 24.369307454176624 1.0628499889712493 1.0144724924414945 0.04738582950290582 0.08099863459647705 399.7539506837298 1288776.382235954 0.02947656847819629 0.028914547571842975 1.762460912476644e-07 6.75388050593029 -0.04837749652975476 SWS(ph)LATFR ddPTM_PC-9_Lapatinib_30min_R1 2 SWSLATFR 8 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 S(0.347)WS(0.653)LATFR;S(0.005)WS(0.995)LATFR 120.27 0.003423 4755600.0 31779.0 28049.0 31564.0 24283.0 27941.3 29384.0 25991.1 22155.7 31568.0 22538.2 True False 31325.825632445147 27984.05426382543 28968.92976056348 26068.85282571335 26297.847668709393 28127.31481744954 27336.79198257099 23185.13470535939 28012.479414222908 26433.897839736248 1.1850626730256635 1.0586427485453522 1.095900798898318 0.9861902691674116 0.9948531929777552 1.0640623258809638 1.034156678228418 0.8770985968821738 1.0597180780548259 1.0 14.69010155441298 -1.5228787471165635 0.5190644851086186 0.9937630892052755 7.597779096196743 0.5043442115665645 0.05379797865839686 96.7885350015027 0.9742254303565568 0.028244141095528898 703.3739796836643 0.02999999987315801 1.5228787471165635 6.6040160069914675 SWS(ph)PPPEVSR ddPTM_PC-9_AZD4547_30min_R2 1 SWSPPPEVSR 10 0 Q9NR19;Q9NR19-2;F8WCJ4;C9JXD9;C9IYL0;B4DEH9;C9JY31 Q9NR19 ACSS2 Acetyl-coenzyme A synthetase, cytoplasmic 1 S(0.01)WS(0.99)PPPEVSR 75.566 0.024332 3528400.0 22815.0 26422.0 33190.0 50784.0 34070.0 35305.0 27260.0 36672.0 30597.0 24267.0 True False 30069.695418519685 34962.39478962875 32749.878914039247 39076.53340497865 29339.968591007902 33097.37276888047 29686.08719038257 31005.18503872606 32214.294954986475 23417.419716299937 1.2840738126920688 1.493007992050158 1.3985263667304624 1.6686950944377112 1.2529121033170667 1.4133654847482067 1.2676924934526095 1.3240222626724574 1.375655189395755 1.0 14.515294498617497 -11.016134787124065 0.24737334790032064 0.6617018296339273 1.4575711733330687 0.524152057638241 0.11391787592887394 17.351952111294015 0.8009963738378505 3.8352037506131977 0.1875255031361563 9.635299371974682e-12 11.016134787124065 0.7958693436991414 SWS(ph)PPPEVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SWSPPPEVSR 10 0 Q9NR19;Q9NR19-2;F8WCJ4;C9JXD9;C9IYL0;B4DEH9;C9JY31 Q9NR19 ACSS2 Acetyl-coenzyme A synthetase, cytoplasmic 1 S(0.247)WS(0.723)PPPEVS(0.03)R;S(0.002)WS(0.994)PPPEVS(0.004)R 69.65 0.037828 58915900.0 43233.0 47836.0 51137.0 54474.0 66499.0 47578.0 46856.0 40095.0 46931.0 41217.0 True False 50551.49300932753 52584.84194288955 52356.30001815247 51421.99838709083 53468.9983170657 45082.925923717856 42417.460471936865 39042.548734164084 47617.277090270916 48689.315826407554 1.0382461152167184 1.080007822052188 1.0753139396088218 1.0561248913504173 1.0981669676300072 0.9259305693358356 0.8711862089656016 0.8018709663812658 0.9779820538050116 1.0 15.57131760780521 -6.836585637347326 5.160951985669122 0.8971129942087613 1.069620607954597 0.6655285765418766 0.05412211265883084 0.11193308596861058 5.345236800633718 0.018706906678608453 0.016619849764102697 1.4568484044320634e-07 6.836585637347326 0.17250761374583556 SWS(ph)PPPEVSR ddPTM_PC-9_Lapatinib_30min_R1 3 SWSPPPEVSR 10 0 Q9NR19;Q9NR19-2;F8WCJ4;C9JXD9;C9IYL0;B4DEH9;C9JY31 Q9NR19 ACSS2 Acetyl-coenzyme A synthetase, cytoplasmic 1 S(0.004)WS(0.884)PPPEVS(0.112)R;S(0.052)WS(0.948)PPPEVSR;S(0.001)WS(0.999)PPPEVSR 103.43 0.0028323 99749500.0 153725.0 152274.0 145802.0 132173.0 150910.0 156869.0 146155.0 143095.0 153633.0 114825.0 True False 151532.8533102876 151921.41890868676 133814.72237199615 141893.4433362029 142033.77050047528 150160.07854949927 153722.19075809265 149743.71609398027 136329.23371278838 134672.34825530465 1.125196488168601 1.1280817545460946 0.9936317596416848 1.053619730957753 1.0546617203942656 1.115003046244013 1.1414532585908008 1.1119113762693447 1.0123030858149342 1.0 17.03909413273366 -8.317868572947917 6.7710943164633886 1.0042384123921873 1.088531591772122 0.3814775811955894 0.04289178997641979 0.3239520950943816 31.508746505515415 0.04501655296232493 0.01182531501164115 4.809848830209314e-09 8.317868572947917 0.08429317937993486 SWS(ph)STPTAGGIEGSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SWSSTPTAGGIEGSVK 16 0 B5MCH3;Q8N3C7 B5MCH3 CLIP4 CAP-Gly domain-containing linker protein 4 1 S(0.383)WS(0.598)S(0.019)T(0.001)PTAGGIEGSVK 168.45 3.905e-05 5456200.0 11377.0 16315.0 18246.0 19084.0 23482.0 18748.0 17526.0 23327.0 16560.0 14158.0 True False 13302.90139400735 17934.64537792129 18681.05383834034 18014.78535116278 18880.870666947438 17764.821876032252 15865.810402748111 22714.690966999533 16802.158671557958 16724.73332533366 0.7954029003175126 1.0723426812883723 1.1169717014287672 1.0771343853880782 1.1289190864614735 1.0621886478227505 0.9486435504903088 1.3581496652381675 1.0046293919740423 1.0 14.02969558693123 -4.761883265499654 4.724588242212329 1.095217555626005 0.773156966215545 0.40458315061867867 0.10531879767952439 0.18030608625936503 9.598378826921667 0.025107722016140897 0.19584608892840433 1.7302813809863287e-05 4.761883265499654 -0.3220605894104601 SWSTAT(ph)SPLGGERPFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SWSTATSPLGGERPFR 16 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;Q9UPQ0-2;Q9UPQ0;D6RD46;D6RJ93;Q6NVB9;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 S(0.007)WS(0.018)T(0.015)AT(0.48)S(0.48)PLGGERPFR 57.61600000000001 0.040964999999999994 6156700.0 8208.6 8261.7 9914.1 14816.0 10788.0 14271.0 14891.0 12985.0 10236.0 10663.0 True False 9598.153852759837 9081.866976326843 10150.489743433627 13985.907554120087 8674.168842305977 13522.603637340319 13480.416678496065 12644.15750874475 10385.682135390536 12596.117491738441 0.7619930394468841 0.7210052607308141 0.8058427328969537 1.1103347966778798 0.6886382925528602 1.0735533108681736 1.070204107522625 1.0038138749529621 0.8245145492015544 1.0 13.62069149910253 -5.572924886061633 8.537885776129459 0.9644635743374905 0.7468167270706135 0.385882195347964 0.11989483527632329 0.26739824303531873 41.57793975599757 0.032273873237648264 0.056142001642982234 2.673468761769514e-06 5.572924886061633 -0.217646847266877 SWSTAT(ph)SPLGGERPFR ddPTM_PC-9_Lapatinib_30min_R1 1 SWSTATSPLGGERPFR 16 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;Q9UPQ0-2;Q9UPQ0;D6RD46;D6RJ93;Q6NVB9;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 SWST(0.001)AT(0.977)S(0.022)PLGGERPFR 135.57 8.285399999999999e-05 4232700.0 13386.0 10953.0 15976.0 14907.0 15038.0 19412.0 18694.0 16889.0 19267.0 20261.0 True False 13195.113185308246 10927.639001450318 14662.514949143388 16003.310508294226 14153.49440584554 18581.794011582166 19661.8838495555 17673.72459632576 17096.947569495456 23763.086853914512 0.5552777409107775 0.45985772255216073 0.6170290517929079 0.6734525108911928 0.5956084111822376 0.7819604467136462 0.8274128681357145 0.7437470015985888 0.7194750275753448 1.0 14.536434635703767 -5.219247600132596 0.1244363832011047 1.1325541396394452 1.846754956984611e-18 0.8038488218198099 0.06452758158925169 13.920101266448405 0.3377713473318013 0.670828494748072 2.8676089538040976 6.0360440409196575e-06 5.219247600132596 -1.1325541396394452 SWSTATS(ph)PLGGERPFR ddPTM_PC-9_AZD4547_30min_R2 3 SWSTATSPLGGERPFR 16 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;Q9UPQ0-2;Q9UPQ0;D6RD46;D6RJ93;Q6NVB9;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 SWS(0.001)T(0.001)AT(0.062)S(0.935)PLGGERPFR;SWST(0.001)AT(0.061)S(0.938)PLGGERPFR;S(0.022)WS(0.018)T(0.018)AT(0.279)S(0.664)PLGGERPFR 90.476 0.01291 79731200.0 59920.0 60584.0 91647.0 97435.0 87544.0 81210.0 64606.0 85014.0 67797.0 76657.0 True False 78973.31358657472 80166.59321530789 90431.70089891394 74972.8661057438 75390.02671943636 76131.92586208154 70355.8088415941 71877.03972737385 71380.61100968125 73973.26176257493 1.0675926909921587 1.0837239200376363 1.2224917320688675 1.0135130494363924 1.0191523926768118 1.0291816806244813 0.9510978313678877 0.9716624360579215 0.9649515150323495 1.0 16.174716270651288 -5.933460750399275 9.998825080883625 0.9905620053935016 1.1204997494956968 0.6541157704426275 0.044186592988642685 0.2512434385604377 35.915164566889544 0.012935192230591605 0.01920494784282781 1.1655723853174781e-06 5.933460750399275 0.12993774410219516 SWSTATS(ph)PLGGERPFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SWSTATSPLGGERPFR 16 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;Q9UPQ0-2;Q9UPQ0;D6RD46;D6RJ93;Q6NVB9;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 SWSTAT(0.08)S(0.919)PLGGERPFR;S(0.001)WS(0.009)T(0.009)AT(0.255)S(0.726)PLGGERPFR 124.25 0.00065125 39453000.0 19069.0 28053.0 26447.0 31932.0 35982.0 33022.0 43135.0 33606.0 29793.0 25067.0 True False 22297.005070082287 30837.916444181792 27077.596780806016 30142.953564940788 28931.585398948235 31290.26818809136 39048.940529643936 32723.878108500274 30228.66626218152 29611.44866973718 0.7529859588690021 1.0414187022095296 0.9144299923589773 1.0179493040388397 0.9770405265081218 1.0566949471833822 1.31871091364577 1.1051089892114596 1.0208438837062077 1.0 14.853867452216926 -6.8173281118368285 3.1922686709582484 1.1267658856984217 0.9460418668692464 0.3513539726120881 0.10894051809515783 0.2720082704755218 5.6353768282331345 0.0400573640596824 0.03609148312406542 1.5229017585211885e-07 6.8173281118368285 -0.18072401882917533 SWSTATS(ph)PLGGERPFR ddPTM_PC-9_Lapatinib_30min_R1 1 SWSTATSPLGGERPFR 16 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;Q9UPQ0-2;Q9UPQ0;D6RD46;D6RJ93;Q6NVB9;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 SWSTAT(0.04)S(0.96)PLGGERPFR 140.93 0.00010783 4017800.0 15405.0 13899.0 14487.0 12711.0 18350.0 16370.0 18228.0 19841.0 19028.0 14493.0 True False 15185.321875069 13866.817719452016 13295.934781437187 13645.809342652972 17270.68907748806 15669.893260333823 19171.756649711024 20762.885293131596 16884.866266277044 16998.095739291388 0.8933542973268394 0.8157865405710494 0.7822014292285345 0.8027845914004621 1.0160366986030422 0.9218616897251966 1.1278767306501976 1.2214830185441203 0.9933386965957244 1.0 14.053085512891226 -6.672092501045371 1.3647691768486392 1.095679054608316 0.8204033726499563 0.6396346295331099 0.08173103604390464 0.24876641673284317 0.9685504286130582 0.03709274599791853 0.036262761802701965 2.127685818663681e-07 6.672092501045371 -0.2752756819583596 SWT(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 1 SWTSPK 6 0 O75494-2;O75494 O75494-2 SRSF10 Serine/arginine-rich splicing factor 10 1 SWT(0.615)S(0.385)PK 67.494 0.019397 15189000.0 122910.0 117850.0 94501.0 106750.0 116480.0 107900.0 106630.0 92023.0 113940.0 96340.0 True False 121157.28086106623 117577.12556568233 86731.49256440903 114600.75110756107 109628.87540849097 103285.36852718503 112150.77965540305 96298.72452647774 101106.87735860875 112992.24063501939 1.0722619551586825 1.0405769892241783 0.7675880403554769 1.0142355834657477 0.9702336619963794 0.914092577921444 0.9925529312907921 0.8522596240704349 0.8948125711144891 1.0 16.785864178212336 -5.027487780027901 24.90480468890106 0.9256288037454321 1.0643408166443404 0.35096007839878196 0.07166314047433077 604.474287214107 547675.0312347197 0.01767699734741628 0.04703515779030062 9.386684481080388e-06 5.027487780027901 0.13871201289890833 SWVIGS(ph)PEILR ddPTM_PC-9_AZD4547_30min_R2 2 SWVIGSPEILR 11 0 Q6P0Q8;Q6P0Q8-2;A0A669KBJ4;E7ERL6 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 SWVIGS(1)PEILR;S(0.184)WVIGS(0.816)PEILR 100.04 0.008739499999999999 3901100.0 34550.9 30302.9 42480.2 54593.0 50426.1 38999.9 36499.5 50274.5 43543.6 42528.6 True False 45537.36749663521 40097.719819492886 41916.8847919304 42007.42730344203 43425.30643284486 36561.23008777969 39747.88479109937 42505.731218080065 45845.22579997873 41039.68665869838 1.1095934497585533 0.9770474163938129 1.0213743867132108 1.0235806051052911 1.0581295806175666 0.8908749813768502 0.9685231059792896 1.0357226060611493 1.1170949276792739 1.0 15.324732095444034 -11.91249862770625 2.0591424823402757 0.8915998598595707 1.0170904604955364 0.004805234202084674 0.06367269417996724 9815688.249349726 1189143.1581564078 4951848.460629608 0.016798631169298864 1.2232109841741858e-12 11.91249862770625 0.12549060063596573 SWVIGS(ph)PEILR ddPTM_PC-9_Lapatinib_30min_R1 2 SWVIGSPEILR 11 0 Q6P0Q8;Q6P0Q8-2;A0A669KBJ4;E7ERL6 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 SWVIGS(1)PEILR;SWVIGS(1)PEILR 98.902 0.011829000000000001 0.0 14747.2 13260.2 14500.400000000001 11564.7 11563.5 14092.1 13495.1 10119.4 17500.1 12067.9 True False 14536.902223694731 13229.496821604267 13308.233085162672 12415.20661670828 10883.357664715713 13489.413733289573 14193.810245968572 10589.584266685944 15529.054453777315 14153.82043553402 1.0270656102997435 0.934694408612873 0.9402573069071549 0.8771629309030341 0.7689342756809594 0.9530581368281024 1.0028253721754272 0.7481785087579714 1.0971634495793579 1.0 13.788903901119877 -9.795416064693637 12.999816106848598 0.9999999999999992 0.9197979687966368 0.0377251907242272 0.10277936418951182 0.0 0.0 0.09560768798686364 0.023188270364172682 1.6017101780516097e-10 9.795416064693637 -0.08020203120336244 SY(ph)STS(ph)LKS(ph)RLT(ph)ISK ddPTM_PC-9_Lapatinib_30min_R1 1 SYSTSLKSRLTISK 14 2 A0A0B4J1V2 A0A0B4J1V2 IGHV2-26 4 S(0.418)Y(0.497)S(0.151)T(0.27)S(0.824)LKS(0.84)RLT(0.958)IS(0.042)K 69.456 0.031051 0.0 7598.7 11962.0 9183.3 8891.0 12822.0 10083.0 7999.5 10604.0 10458.0 8089.6 True False 7490.34114456908 11934.302723943088 8428.284522563128 9544.87379950654 12067.835169021908 9651.773594621009 8413.674968145893 11096.700551805225 9280.109912377826 9487.876581285562 0.7894644371052911 1.257847593368046 0.8883214753433414 1.0060073734868562 1.2719216007536613 1.0172743618586615 0.8867816624787799 1.1695662835341893 0.9781018790529435 1.0 13.211869528027734 -4.72372412205776 24.273810041372485 1.052104332742581 0.7894609463876731 0.2684703390841736 0.13043501929892815 6836.4578117470055 4399588.53470756 0.03152817118639201 8.45906796141671 1.889191043444598e-05 4.72372412205776 -0.2626433863549079 SY(ph)TEKR ddPTM_PC-9_AZD4547_30min_R2 1 SYTEKR 6 1 A0A087WWW8;Q9Y6J0-2;Q9Y6J0 A0A087WWW8 CABIN1 Calcineurin-binding protein cabin-1 1 S(0.324)Y(0.587)T(0.089)EKR 68.485 0.027348 0.0 1304.7 1034.4 32868.0 52000.0 31102.0 20938.0 6412.2 38971.0 11921.0 14874.0 True False 1719.5674605541365 1368.7495712055093 32432.1488444303 40012.203391991374 26784.024159598714 19628.743550058618 6982.873377922635 32948.92741449042 12551.119722796153 14353.265787293256 0.11980322011987302 0.09536154290525603 2.259565824604323 2.7876724353152866 1.866057840530636 1.36754546602458 0.4865006669147362 2.295570074627869 0.8744434826746873 1.0 13.809091409069644 -5.247422131958739 24.360445090138906 1.6648361949129487 0.1075818862031176 0.4411114556120188 0.6779869635199249 525.6324940871781 913486.0671360461 0.18110444003996812 0.473539476819786 5.6568917481634775e-06 5.247422131958739 -1.557254308709831 SY(ph)Y(ph)DILGVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SYYDILGVPK 10 0 Q9UBS3 Q9UBS3 DNAJB9 DnaJ homolog subfamily B member 9 2 S(0.209)Y(0.814)Y(0.977)DILGVPK 60.43600000000001 0.037984 10704000.0 58467.0 59022.0 75153.0 89846.0 102570.0 82422.0 78609.0 92868.0 76430.0 76692.0 True False 68364.30832411235 64881.31409719098 76944.93253933979 84812.21990466226 82472.14480490569 78099.64522436155 71162.5864401247 90430.31340177964 77547.64415864598 90595.652506462 0.7546091499173878 0.7161636601995127 0.8493225713436026 0.9361621397739012 0.9103322568268177 0.8620683560813348 0.7854967039952476 0.998174977494968 0.8559753367096139 1.0 16.46715419960178 -5.4059288526488745 3.762592557580026 0.8998216993926968 0.7359648711097447 0.5404461798032587 0.062146132811584584 0.1767646002944385 4.393842952771587 0.016410024695734465 0.03696787763452683 3.927092648733188e-06 5.4059288526488745 -0.16385682828295212 SYCAEIAHNVSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SYCAEIAHNVSSK 13 0 D3YTB1;F8W727;P62910 D3YTB1 RPL32 60S ribosomal protein L32 0 89.44 0.0051242 4220300.0 27375.0 29316.0 49320.0 49878.0 59617.0 52792.0 45319.0 43640.0 42510.0 33298.0 False True 32009.04681910444 32226.29873730559 50495.97584714158 47083.49736665784 47935.47681421534 50023.49458499541 41026.056238853205 42494.49624040209 43131.628328981205 39334.66381317704 0.8137617997991244 0.8192849668263809 1.2837525722089818 1.1969975792925158 1.218657341064068 1.2717407430399248 1.0430000478384553 1.0803320054350258 1.0965297309731217 1.0 15.263513632731824 -5.2472906854609755 24.71527400833063 1.1565627750039755 0.8165232906649759 0.6830927853517907 0.09042824452757277 387.0904249551877 676175.5191819755 0.024051584946752302 0.06295411458812403 5.658604160314971e-06 5.2472906854609755 -0.34003948433899966 SYCAEIAHNVSSK ddPTM_PC-9_Lapatinib_30min_R1 2 SYCAEIAHNVSSK 13 0 D3YTB1;F8W727;P62910 D3YTB1 RPL32 60S ribosomal protein L32 0 ; 143.94 7.4584e-05 20140000.0 218811.0 208214.0 245107.0 223841.0 236782.0 269250.0 232306.0 209605.0 262680.0 203587.0 False True 215690.71501497686 207731.8932756298 224955.24860038175 240303.01385168653 222854.94829132324 257734.80515240564 244333.66799801216 219344.01350067244 233094.21225697157 238776.74168737401 0.9033154296802355 0.8699837840471469 0.9421154129614161 1.0063920470374406 0.9333193288276925 1.0793966084429323 1.023272477341674 0.9186154897274522 0.9762014952116129 1.0 17.865302790577026 -5.50450401160341 3.5117108054425636 0.9900901645506602 0.8876350657494282 0.48291082576684563 0.04317968123595128 0.20562559309934303 5.319982950403079 0.01246153865671359 0.02619381241851094 3.1296515626564913e-06 5.50450401160341 -0.10245509880123205 SYCNDQSTGDIK ddPTM_PC-9_Lapatinib_30min_R1 1 SYCNDQSTGDIK 12 0 P00492 P00492 HPRT1 Hypoxanthine-guanine phosphoribosyltransferase 0 173.76 1.8479e-18 0.0 8999.3 9526.8 9127.0 7993.4 8067.0 7166.7 8293.4 7783.1 11658.0 10804.0 False True 8870.968331730499 9504.741279924845 8376.613291238848 8581.261301200711 7592.514920332219 6860.196947393667 8722.791672082141 8144.731239603477 10344.953275817623 12671.457004574911 0.7000748476302069 0.7500906388660157 0.6610615723365157 0.6772118863760124 0.5991824710916047 0.5413897505959147 0.6883811126796909 0.642762015186012 0.8163980884031469 1.0 13.62929479924696 -8.53757886007836 2.4839590376095018 0.9994404557869632 0.6559831122013692 0.7985918771693659 0.05427140176444375 0.1347549558933498 1.9857586248314776 0.05760863288611291 0.01565131974725542 2.9001545348989866e-09 8.53757886007836 -0.343457343585594 SYDYDLIIIGGGSGGLAAAK ddPTM_PC-9_Lapatinib_30min_R1 1 SYDYDLIIIGGGSGGLAAAK 20 0 Q16881;Q16881-5;A0A182DWI3;Q16881-2;F8W809;Q16881-3;Q16881-6;Q16881-4;A0A087WSW9;E9PIR7;A0A087WSY9;E9PKD3;A0A0B4J225;E9PIZ5;E9PKI4;E9PLT3;E9PQI3 Q16881 TXNRD1 Thioredoxin reductase 1, cytoplasmic 0 227.41 9.419999999999997e-102 0.0 3472.3 2891.3 3660.4 2469.9 4177.5 4174.7 3902.5 3196.6 4348.8 2852.1 False True 3422.7843652581664 2884.605372490941 3359.456041552609 2651.5446853448657 3931.7876632810007 3996.157812701012 4104.552354920851 3345.1257057620305 3858.992349105822 3345.0816848156333 1.0232289336297078 0.8623422816803137 1.0042971616514553 0.7926696371514789 1.1753936177787851 1.1946368397641278 1.2270409938127047 1.0000131599017736 1.1536317234413107 1.0 11.707825725675177 -6.276866826545729 24.9964150150106 1.1336920082079407 0.9224466734205846 0.5327431706211829 0.09360540163450772 601.9810933793586 975361.2756781976 0.028268662248619316 0.032165330281446226 5.286073207712131e-07 6.276866826545729 -0.21124533478735608 SYELPDGQVIT(ph)IGNER ddPTM_PC-9_AZD4547_30min_R2 1 SYELPDGQVITIGNER 16 0 P60709;A0A2R8Y793;Q6S8J3;A5A3E0;P63267-2;A0A2R8YEA7;Q9BYX7;Q562R1;P63261;P68133;P68032;P63267;P62736 P60709;P63261;P68133 ACTB;POTEE;POTEF;ACTG2;POTEKP;ACTBL2;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Actin, gamma-enteric smooth muscle;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 1 SYELPDGQVIT(1)IGNER 138.98 4.1951000000000005e-05 5060200.0 9570.8 11737.0 11701.0 20454.0 14798.0 13451.0 10062.0 13342.0 9646.3 9958.9 True False 12614.115314993129 15530.755720455396 11545.837094702416 15738.646311149841 12743.55313207324 12609.906843625866 10957.498507323162 11280.300468659552 10156.183724688242 9610.241942253242 1.3125700050830968 1.6160629268001565 1.201409617372791 1.6376951179503518 1.3260387416516337 1.3121320898471902 1.140189661526257 1.1737790303762887 1.0568083286264276 1.0 13.230357036628352 -7.292378118918634 0.9369795820514185 1.039111014828582 1.4437281302254816 0.608594356270832 0.12671992666098064 0.37749618116864464 0.6398067905720397 0.09132489492893908 0.05131460381646813 5.100607217278244e-08 7.292378118918634 0.4046171153968996 SYELPDGQVIT(ph)IGNER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SYELPDGQVITIGNER 16 0 P60709;A0A2R8Y793;Q6S8J3;A5A3E0;P63267-2;A0A2R8YEA7;Q9BYX7;Q562R1;P63261;P68133;P68032;P63267;P62736 P60709;P63261;P68133 ACTB;POTEE;POTEF;ACTG2;POTEKP;ACTBL2;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Actin, gamma-enteric smooth muscle;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 1 SYELPDGQVIT(1)IGNER;SYELPDGQVIT(1)IGNER 120.9 0.00020590000000000002 5931700.0 32485.1 39988.0 38250.7 43382.0 47148.0 41883.0 41805.0 37021.0 41585.0 35174.0 True False 37984.18582002885 43957.74436851468 39162.74175458755 40951.44718634164 37909.687854749915 39686.58174919238 37844.92775801006 36049.23797699187 42193.101953909274 41550.76776276922 0.914163272190216 1.0579285711274435 0.9425275118424788 0.9855761852621028 0.912370333833354 0.955134739646202 0.9108117562130896 0.867594990851002 1.0154590209934846 1.0 15.342587514482645 -6.246711278778963 24.129229751055433 0.9358827001210188 0.9786459115486486 0.06486866299289229 0.05334320418179898 1075.3204975581893 1761708.7806779721 0.015011016726680246 0.01928486651104446 5.666158530074634e-07 6.246711278778963 0.04276321142762973 SYELPDGQVIT(ph)IGNER ddPTM_PC-9_Lapatinib_30min_R1 2 SYELPDGQVITIGNER 16 0 P60709;A0A2R8Y793;Q6S8J3;A5A3E0;P63267-2;A0A2R8YEA7;Q9BYX7;Q562R1;P63261;P68133;P68032;P63267;P62736 P60709;P63261;P68133 ACTB;POTEE;POTEF;ACTG2;POTEKP;ACTBL2;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Actin, gamma-enteric smooth muscle;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 1 SYELPDGQVIT(1)IGNER;SYELPDGQVIT(1)IGNER 124.29 8.7771e-05 9668000.0 17159.9 13931.1 16270.6 11622.8 19455.7 17188.6 14886.2 16825.5 15572.6 13549.0 True False 16915.196679259752 13898.843393874226 14932.894074332278 12477.57948452419 18311.353977377898 16453.483646583612 15656.934597264002 17607.274154507624 13818.649801252142 15890.926597092326 1.064456284277019 0.8746402111263539 0.9397119785994514 0.7852015052921647 1.1523150563623177 1.0354011483253733 0.9852751192072626 1.1080080224981563 0.8695937091409532 1.0 13.955915629978804 -6.2633412271851014 24.994544881649375 1.029023167769931 0.9147415850840144 0.23811599950427798 0.09543633747617046 239.06079683598645 3141789.7008653106 0.028100788057022052 0.03347100905501918 5.453292250258165e-07 6.2633412271851014 -0.1142815826859167 SYELPDGQVITIGNER ddPTM_PC-9_AZD4547_30min_R2 4 SYELPDGQVITIGNER 16 0 P60709;A0A2R8Y793;Q6S8J3;A5A3E0;P63267-2;A0A2R8YEA7;Q9BYX7;Q562R1;P63261;P68133;P68032;P63267;P62736 P60709;P63261;P68133 ACTB;POTEE;POTEF;ACTG2;POTEKP;ACTBL2;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Actin, gamma-enteric smooth muscle;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 0 ;;; 187.63 2.1834e-07 261166000.0 313047.0 281032.0 436975.0 573940.0 475870.0 414790.0 353308.0 449857.0 358558.0 385263.0 False True 412589.4342178979 371870.09811970894 431180.4259856067 441627.000284606 409803.66461411596 388853.11572876107 384751.7275517131 380341.93733546586 377510.6438693346 371775.0596349315 1.1097824437794308 1.0002556343743736 1.1597884656625674 1.1878876456055616 1.1022892848609238 1.0459365297677568 1.0349046219763214 1.0230431748405788 1.0154275659051342 1.0 18.504070465383094 -6.8478532681812645 2.96275669709747 1.0218865632221816 1.1134366120038168 0.4859347498451624 0.04607701049633605 0.26410037584831136 4.677364639399537 0.01913463336667362 0.016929672994520563 1.4195370490114566e-07 6.8478532681812645 0.0915500487816352 SYELPDGQVITIGNER ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SYELPDGQVITIGNER 16 0 P60709;A0A2R8Y793;Q6S8J3;A5A3E0;P63267-2;A0A2R8YEA7;Q9BYX7;Q562R1;P63261;P68133;P68032;P63267;P62736 P60709;P63261;P68133 ACTB;POTEE;POTEF;ACTG2;POTEKP;ACTBL2;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Actin, gamma-enteric smooth muscle;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 0 ;;;;; 167.22 8.978799999999999e-05 220640000.0 272176.6 299327.1 331443.0 356140.0 354530.0 314456.7 335946.4 280298.9 279794.4 264178.1 False True 318250.7226471116 329042.3163041114 339345.858124578 336186.6304214594 285062.3915148997 297966.03708261764 304123.12495068886 272941.3508762341 283885.86378099985 312071.4982973116 1.019800668704173 1.0543811853994807 1.087397791775531 1.077274381850704 0.9134521834586757 0.9548005463758961 0.9745302810734408 0.8746115949884086 0.9096821251857509 1.0 18.251517075388925 -6.260114410721136 24.996329977511607 0.93425862859666 1.061310080049366 0.7223505237566056 0.0369687121000951 63.30829324013097 1194350.6675455198 0.011476624755459202 0.014003629024342828 5.493961216461062e-07 6.260114410721136 0.12705145145270602 SYELPDGQVITIGNER ddPTM_PC-9_Lapatinib_30min_R1 4 SYELPDGQVITIGNER 16 0 P60709;A0A2R8Y793;Q6S8J3;A5A3E0;P63267-2;A0A2R8YEA7;Q9BYX7;Q562R1;P63261;P68133;P68032;P63267;P62736 P60709;P63261;P68133 ACTB;POTEE;POTEF;ACTG2;POTEKP;ACTBL2;ACTG1;ACTA1;ACTC1;ACTA2 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Actin, gamma-enteric smooth muscle;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle 0 ;;; 157.09 9.554700000000001e-05 564562000.0 214241.0 188680.1 223421.0 208336.0 217951.0 219727.3 205011.6 197408.4 220277.0 182635.9 False True 211185.88405301288 188243.2228209209 205052.18781000088 223657.7244285231 205131.55068815287 210330.07558835344 215626.09751853693 206580.714938795 195467.08464035657 214204.27196795985 0.9859088341832956 0.8788023744413364 0.957274035322097 1.0441328848099596 0.9576445362342537 0.9819135428812275 1.006637708657789 0.9644098739995943 0.9125265469476447 1.0 17.70862772709983 -5.519912714388152 24.99158738361097 0.9813003018604625 0.9287762487268101 0.18973616706502705 0.04034377775558782 161.88744406723654 1364053.2699764231 0.010671232393398912 0.018958789176390326 3.0205587389936844e-06 5.519912714388152 -0.05252405313365238 SYEPLEDPGVK ddPTM_PC-9_Lapatinib_30min_R1 2 SYEPLEDPGVK 11 0 P37837;F2Z393 P37837 TALDO1 Transaldolase 0 ; 121.5 0.0035085 12070900.0 132273.0 132733.0 129946.0 127965.0 134583.0 123362.0 154917.0 119420.0 128428.0 128605.0 False True 130386.76276410259 132425.6648935911 119262.34148606576 137375.97297872583 126667.09254035851 118086.09483086735 162937.84424529728 124968.68916414396 113963.08623320506 150834.20289460904 0.8644376425365969 0.8779551477864714 0.790684998477413 0.9107746806917079 0.8397769876429381 0.7828867230688821 1.080244673412338 0.8285169196767801 0.7555520170238404 1.0 17.20260408309243 SYES(ph)SEDCSEAAGSPAR ddPTM_PC-9_Lapatinib_30min_R1 1 SYESSEDCSEAAGSPAR 17 0 Q6P6C2-3;Q6P6C2;K7ER58 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 S(0.003)YES(0.498)S(0.498)EDCSEAAGSPAR 263.45 3.647699999999999e-69 5737800.0 14387.0 18308.0 19110.0 16672.0 22364.0 21548.0 23235.0 23868.0 22979.0 19187.0 True False 14181.838741747319 18265.608950840167 17538.849566733254 17898.114496161616 21048.593489315692 20626.44227084137 24437.994610271853 24976.994414417863 20390.863040402575 22503.44738492956 0.6302073855246206 0.8116804789239781 0.7793850100708982 0.7953498941743428 0.9353497323886394 0.9165903302733424 1.0859667051119397 1.1099185821255468 0.9061217462200137 1.0 14.457858409621373 -6.300052630545271 0.9378126905139473 1.0326383835752933 0.7179063757118392 0.7505285092603025 0.06996398047901392 0.28360807551560846 0.5332426399814463 0.0343421337617704 0.05247179027402754 5.01126500276422e-07 6.300052630545271 -0.314732007863454 SYESS(ph)EDCSEAAGSPAR ddPTM_PC-9_AZD4547_30min_R2 1 SYESSEDCSEAAGSPAR 17 0 Q6P6C2-3;Q6P6C2;K7ER58 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 S(0.002)YES(0.075)S(0.923)EDCSEAAGSPAR 271.45 4.0409999999999994e-70 5108700.0 17092.0 16998.0 21546.0 26602.0 20291.0 21497.0 24507.0 25514.0 20824.0 19751.0 True False 22526.900464314647 22492.27108599308 21260.2859620937 20469.31989680297 17473.944898155012 20152.78919169023 26688.07552365024 21571.397553393756 21924.714126961422 19059.523501736523 1.1819235912305053 1.1801066844060293 1.1154678636198154 1.073968081885048 0.9168091162700344 1.0573605992749031 1.400248832097963 1.1317910204538102 1.1503285549066244 1.0 14.218224431101877 SYESSEDCSEAAGS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 2 SYESSEDCSEAAGSPAR 17 0 Q6P6C2-3;Q6P6C2;K7ER58 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 SYESSEDCSEAAGS(1)PAR;SYESSEDCSEAAGS(1)PAR 278.89 6.316599999999999e-83 45658000.0 16172.4 15824.6 17709.7 23450.0 22675.9 18367.4 15520.5 22633.0 16744.5 21823.6 True False 21314.886793182908 20939.59248308073 17474.85780668759 18043.96479888841 19527.74269952558 17218.883574426713 16901.794432807503 19135.589904599874 17629.580085425743 21059.562406586858 1.012123916996309 0.9943033040672961 0.8297825695191999 0.8568062550646707 0.9272625101373347 0.8176277950125457 0.8025710176922328 0.9086413827200314 0.8371294590580709 1.0 14.362187838685823 -5.246007652274054 19.3204013514187 0.8661561769083883 1.003214591903995 0.4558472058693168 0.05680054689774233 32.973731077948045 41277.348448749566 0.013744439701540259 0.035750807210178336 5.675346053537969e-06 5.246007652274054 0.13705841499560667 SYESSEDCSEAAGS(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SYESSEDCSEAAGSPAR 17 0 Q6P6C2-3;Q6P6C2;K7ER58 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 SYESSEDCSEAAGS(1)PAR;SYESSEDCSEAAGS(1)PAR 222.09 2.613e-23 36920000.0 16111.0 11779.6 19894.0 15855.0 17772.4 16016.400000000001 14037.0 15043.7 14416.5 14392.7 True False 18838.274093245353 12949.000839335687 20368.34840841513 14966.695752603546 14290.025800240888 15176.471788739222 12707.313740920637 14648.818815117698 14627.314039161554 17001.98257744948 1.1080045522591837 0.7616171102604558 1.1979984284556686 0.880291206300527 0.8404917329579208 0.8926295342090564 0.7474018799298701 0.8615947433417035 0.8603299040291008 1.0 14.053415366376127 -5.971857365341131 24.99991707179996 0.8558977492313966 1.0035639816402986 0.2528069216247739 0.11892281400455919 288.5822470221874 256354.09345859295 0.03142450581448697 0.04660917818988073 1.066946479260292e-06 5.971857365341131 0.14766623240890198 SYESSEDCSEAAGS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 2 SYESSEDCSEAAGSPAR 17 0 Q6P6C2-3;Q6P6C2;K7ER58 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 SYESSEDCSEAAGS(1)PAR;SYESSEDCSEAAGS(1)PAR 268.17 1.7335999999999995e-69 40747000.0 8015.3 12973.4 17842.0 11101.3 16468.0 12033.3 13670.7 14122.6 12429.1 10168.0 True False 7901.000352174005 12943.360889383315 16375.099632111689 11917.726634851184 15499.384617333699 11518.663809992358 14378.501954751166 14778.787553086051 11029.20387377464 11925.525251991641 0.6625284996025216 1.0853493339609246 1.3731134927895055 0.9993460567165245 1.2996815058309654 0.965883142804856 1.2056912924946313 1.2392567405463248 0.9248400922158704 1.0 13.541765189742952 -4.771941996579313 4.796453775900016 1.1389551454965723 0.632890066864792 0.4740631798654604 0.14494389408358577 0.13805015755214184 7.731346516837182 0.033696260299491514 0.23372266291733526 1.6906667183125496e-05 4.771941996579313 -0.5060650786317803 SYESSEDCSEAAGS(ph)PARK ddPTM_PC-9_Lapatinib_30min_R1 1 SYESSEDCSEAAGSPARK 18 1 Q6P6C2-3;Q6P6C2;K7ER58 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 SYESSEDCS(0.001)EAAGS(0.999)PARK 59.261 0.013456999999999998 9869800.0 10327.0 14797.0 17519.0 17198.0 15994.0 14124.0 12192.0 13833.0 14014.0 12629.0 True False 10179.735086260143 14762.738455624967 16078.655445295646 18462.798290846193 15053.26436541386 13519.949444652102 12823.242104085835 14475.731679849268 12435.59574603776 14811.905822915263 0.6872670679900784 0.9966805509109955 1.085522392427085 1.2464836403619777 1.016294901235815 0.9127758173924927 0.8657388358658885 0.9773037887841614 0.8395675677871816 1.0 13.854469661254734 -6.750654955005531 7.377910450663247 0.9141573389134856 1.0239173207030885 0.0855199284730318 0.13664127647040114 0.3280549023259886 96.77681896825146 0.04890025142290381 0.04684175976323436 1.7755996264820743e-07 6.750654955005531 0.10975998178960289 SYIEGYVPSQADVAVFEAVSSPPPADLCHALR ddPTM_PC-9_Lapatinib_30min_R1 2 SYIEGYVPSQADVAVFEAVSSPPPADLCHALR 32 0 P24534;C9JZW3;F2Z2G2 P24534 EEF1B2 Elongation factor 1-beta 0 ; 104.91 1.4872e-15 4188000.0 16154.9 14006.8 19879.3 15266.0 20592.5 18621.9 18476.8 16772.4 15919.1 16781.1 False True 15924.528163554176 13974.36811517522 18244.90069031713 16388.71256588313 19381.289636412697 17825.48474676911 19433.438296323257 17551.706934656544 14126.123322445388 19681.690775589792 0.8091036662004956 0.7100186805346482 0.9269986455099355 0.8326882457786209 0.9847370257666244 0.9056886905710947 0.9873866284102771 0.8917784114576701 0.7177291566822758 1.0 14.264566541729728 -5.268147642340138 24.909104816452853 0.9051178394867849 0.7595611708205394 0.33483186234151696 0.08248425079817194 503.25234200150874 1868681.4553087687 0.021288998565075573 0.04597451614601075 5.393272421682952e-06 5.268147642340138 -0.1455566686662455 SYISLISS(ph)ERPVHNWR ddPTM_PC-9_Lapatinib_30min_R1 2 SYISLISSERPVHNWR 16 1 C9JVA0;Q6ZU64-5 C9JVA0 CCDC108 1 S(0.006)Y(0.005)IS(0.036)LIS(0.177)S(0.775)ERPVHNWR;SYISLISS(1)ERPVHNWR 67.095 0.012066 14070400.0 56573.0 63486.0 56934.0 52757.0 43391.0 57418.0 62874.0 73488.0 54647.0 35638.0 True False 55766.25864578239 63339.002067568224 52253.10629159554 56636.925772192815 40838.82668998829 54962.3659878954 66129.30807515532 76902.52076113384 48492.07940157881 41797.98081534992 1.3341854692010087 1.515360331576294 1.2501347020190525 1.355015832520633 0.9770526205655994 1.3149526583760474 1.5821172885669623 1.839862100058482 1.1601536355500348 1.0 15.351145629557935 -7.098365437237525 8.111560997041604 1.4643601643938515 1.2857528594403813 0.01252665394837904 0.24889894404033988 0.7548553480241459 56.073594790029844 0.09439720085726214 0.07312893345225314 7.973234967969345e-08 7.098365437237525 -0.17860730495347021 SYLEGS(ph)SDNQLKDSESTPVDDR ddPTM_PC-9_Lapatinib_30min_R1 2 SYLEGSSDNQLKDSESTPVDDR 22 1 Q9UHI6;E9PJ60 Q9UHI6 DDX20 Probable ATP-dependent RNA helicase DDX20 1 SYLEGS(0.5)S(0.5)DNQLKDSESTPVDDR;S(0.003)Y(0.002)LEGS(0.497)S(0.497)DNQLKDSESTPVDDR 100.67 4.2823e-05 16540400.0 48744.0 44484.0 39688.0 43262.0 48226.0 39690.0 33933.0 35552.0 47895.0 48078.0 True False 48048.901621445155 44381.00003108879 36425.00584011037 46443.63179780133 45389.44149596402 37992.551221908936 35689.88470455585 37203.875708956926 42500.560743290844 56388.2182400919 0.8521088823353261 0.7870615780431593 0.6459683773837044 0.8236407045183068 0.8049454817441319 0.6737675423639529 0.6329315913582179 0.6597810122417568 0.753713489621721 1.0 15.783106136815416 -8.573176987915728 20.948478157195076 1.0000000009067223 0.7319507921782656 0.5227586259647075 0.0754996526914619 4098.202900262008 1706838.6414486847 0.07833219992608187 0.020225287098845555 2.6719173010031575e-09 8.573176987915728 -0.2680492087284566 SYLLGNS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SYLLGNSSPR 10 0 P02545;P02545-3;P02545-5;P02545-4;A0A0C4DGC5 P02545 LMNA Prelamin-A/C;Lamin-A/C 1 SYLLGNS(0.696)S(0.304)PR 87.789 0.010403 6703400.0 56662.0 59342.0 55379.0 57889.0 60956.0 59724.0 57996.0 66875.0 52466.0 39900.0 True False 66253.75747448752 65233.081582384664 56699.44538602702 54645.66700867021 49012.10937630729 56591.968301906876 52502.19902532117 65119.602109919564 53233.21599407967 47133.55415177378 1.4056601218984073 1.3840051478470936 1.2029528943107137 1.1593792997809338 1.0398560061582545 1.2006726273956818 1.1139028229498655 1.3815975324124568 1.1294123040809632 1.0 15.524466852835868 -5.2961365856125076 2.979263057916486 1.1594863663781094 1.4060206496985208 0.5030740245889932 0.09686101596761325 0.2208453691048722 3.887547990196953 0.026213542281694056 0.07335805049919336 5.0566560516230174e-06 5.2961365856125076 0.24653428332041138 SYLLGNSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SYLLGNSSPR 10 0 P02545;P02545-3;P02545-5;P02545-4;A0A0C4DGC5 P02545 LMNA Prelamin-A/C;Lamin-A/C 1 SYLLGNS(0.3)S(0.7)PR;SYLLGNS(0.317)S(0.683)PR 98.04 0.0049128 16880900.0 153432.0 147267.0 115240.0 127830.0 146134.0 143489.0 135067.0 158118.0 132910.0 107140.0 True False 179405.0071798664 161886.69450630317 117987.75865013352 120668.09953045165 117500.09173169661 135964.184242052 122272.47595960146 153967.57003986905 134853.55730898347 126563.63388022664 1.4175083448508292 1.2790932872510952 0.9322406052420327 0.9534184175262049 0.928387469048911 1.0742752880398612 0.966094858459215 1.2165229878400623 1.0655000427421513 1.0 16.9495034024458 -5.088553277334364 3.9786645409106054 1.0203507478903753 1.394270530259691 0.7251958596578806 0.08330589851323181 0.11856874055050913 3.337148078083797 0.023343933061879145 0.07600375649969698 8.155427338050104e-06 5.088553277334364 0.37391978236931567 SYLLGNSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 SYLLGNSSPR 10 0 P02545;P02545-3;P02545-5;P02545-4;A0A0C4DGC5 P02545 LMNA Prelamin-A/C;Lamin-A/C 1 SYLLGNS(0.009)S(0.991)PR;SYLLGNS(0.229)S(0.771)PR 113.67 0.0012735 9177000.0 113638.0 99810.0 96501.0 86571.0 94238.0 87736.0 80848.0 84589.0 91220.0 90455.0 True False 112017.5012813428 99578.89607730815 88567.06028463248 92937.72013239007 88695.10611903662 83983.7358026053 85033.9138476978 88519.31374732684 80945.8430108152 106090.02622628877 1.0558721235718314 0.9386263687493822 0.8348292807065575 0.8760269314492863 0.8360362352050984 0.7916270623165742 0.8015259951611423 0.8343792239104192 0.7629920162161019 1.0 16.694929505899402 -4.578121716885073 1.1356134546807684 0.8289293431309132 1.2567242248866628 0.5366681444557059 0.06165124700323776 1.6543304278196624 1.3239553563854767 0.0177364658888088 0.9428587871558886 2.6416682904022328e-05 4.578121716885073 0.42779488175574965 SYLS(ph)QPR ddPTM_PC-9_AZD4547_30min_R2 1 SYLSQPR 7 0 B4DTR8;Q9Y5X9 B4DTR8 LIPG Endothelial lipase 1 S(0.001)Y(0.001)LS(0.998)QPR 65.672 0.031866000000000005 2211500.0 0.0 0.0 0.0 0.0 0.0 399.54 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 374.5567006395272 0.0 0.0 0.0 0.0 0.0 SYMNPGDQS(ph)PADSNK ddPTM_PC-9_AZD4547_30min_R2 2 SYMNPGDQSPADSNK 15 0 Q92754-2;Q92754 Q92754-2 TFAP2C Transcription factor AP-2 gamma 1 SYMNPGDQS(0.593)PADS(0.407)NK;SYMNPGDQS(0.993)PADS(0.007)NK 154.31 1.9265999999999998e-05 12859700.0 48251.0 54990.0 62734.0 62939.0 66025.0 62289.0 67725.0 79942.0 63866.0 62000.0 True False 63593.814316852666 72764.44211194023 61902.1061703326 48429.38594785663 56858.568424458375 58394.05898316941 73752.39379929067 67588.80078440877 67241.82637497687 59829.398871331265 1.0629191587503182 1.2161987832842343 1.0346436256773845 0.809458006623275 0.95034497248983 0.9760094549629574 1.232711596482895 1.1296921256014092 1.1238927290509257 1.0 15.868566947310727 -7.239578448794862 24.692239846256435 1.1323818054378303 1.0072439666771644 0.20383005990280756 0.10886472347467079 1140.0639394220393 1287719.902177816 0.04603569263579258 0.03562979674377229 5.759987636107377e-08 7.239578448794862 -0.12513783876066586 SYMNPGDQS(ph)PADSNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SYMNPGDQSPADSNK 15 0 Q92754-2;Q92754 Q92754-2 TFAP2C Transcription factor AP-2 gamma 1 SYMNPGDQS(1)PADSNK;SYMNPGDQS(0.593)PADS(0.407)NK 151.11 6.5802e-10 5609200.0 32040.0 38240.0 30891.0 31657.0 37563.0 25660.0 31844.0 26890.0 23116.2 24727.0 True False 37463.73918115456 42036.21448064422 31627.558594769893 29883.36092337875 30202.799798251686 24314.34442815167 28827.50578940492 26184.165992310063 23454.230693446145 29209.809361175718 1.282573902414768 1.439112935003155 1.0827718251666418 1.0230590879205903 1.0339951016043194 0.8324033932405303 0.9869118087337148 0.896416873816123 0.8029573354429484 1.0 14.83416532194852 -5.557450713542748 1.2630248569970157 0.9146780460317816 1.3914045949984035 0.7915175264270576 0.08475617381952628 0.22403396980034943 0.6524233459402948 0.027480194416096365 0.09659209044150767 2.7704434285920715e-06 5.557450713542748 0.4767265489666219 SYMNPGDQS(ph)PADSNK ddPTM_PC-9_Lapatinib_30min_R1 5 SYMNPGDQSPADSNK 15 0 Q92754-2;Q92754 Q92754-2 TFAP2C Transcription factor AP-2 gamma 1 SYMNPGDQS(0.996)PADS(0.004)NK;SYMNPGDQS(0.534)PADS(0.465)NK;SYMNPGDQS(0.999)PADS(0.001)NK;SYMNPGDQS(0.974)PADS(0.026)NK;SYMNPGDQS(0.973)PADS(0.027)NK 174.68 6.7186e-05 20596700.0 63261.7 94523.0 102521.0 92740.5 95516.6 106955.0 98944.1 98928.1 98182.8 84124.1 True False 62359.57655722504 94304.1378009756 94092.11912250427 99560.94574323898 89898.50138086079 102380.78397428244 104066.94136080059 103524.660680785 87124.41915328061 98664.83859668259 0.6320344455448362 0.9558028892792046 0.9536540115078842 1.009082335301023 0.9111503414944364 1.037662306354037 1.054752055959879 1.0492558661547926 0.8830341223120391 1.0 16.59024841944894 -4.740476723696376 3.490813381182209 0.9900374757280491 0.5688932986232661 0.7915795871177252 0.0543299609606397 0.15857357961531077 2.929824452232815 0.013980709680737793 0.18778445747543182 1.817704474573585e-05 4.740476723696376 -0.421144177104783 SYS(ph)AGNASQLEQLSR ddPTM_PC-9_AZD4547_30min_R2 2 SYSAGNASQLEQLSR 15 0 Q14678-2;Q14678 Q14678-2 KANK1 KN motif and ankyrin repeat domain-containing protein 1 1 S(0.003)Y(0.002)S(0.995)AGNASQLEQLSR;S(0.426)YS(0.573)AGNAS(0.001)QLEQLSR 106.31 0.00095606 50342000.0 84964.0 71323.0 115983.0 168734.0 146145.0 112297.0 110625.0 125791.0 106518.0 118254.0 True False 111980.78463901392 94376.76495271713 114444.98963805396 129834.98321431286 125855.28939632673 105275.05083775573 120470.41069097858 106352.89133961554 112148.32401919318 114113.96345371616 0.9813065925488825 0.8270395847831163 1.002900838550508 1.1377659603153916 1.1028912289719284 0.9225431108652585 1.0557026243316887 0.9319884098386569 0.9827747685293551 1.0 16.80011581096145 -5.422210444631743 7.8386411637757885 1.0212214129854287 0.9052645870363583 0.2796987482958684 0.07279124578873387 0.3597644175382981 24.966189665595053 0.019825651922027506 0.041426179283775365 3.7825924847619564e-06 5.422210444631743 -0.11595682594907042 SYS(ph)AGNASQLEQLSR ddPTM_PC-9_Lapatinib_30min_R1 2 SYSAGNASQLEQLSR 15 0 Q14678-2;Q14678 Q14678-2 KANK1 KN motif and ankyrin repeat domain-containing protein 1 1 S(0.311)YS(0.688)AGNAS(0.001)QLEQLSR;S(0.099)YS(0.901)AGNAS(0.001)QLEQLSR 112.44 0.0003182 42853000.0 77671.0 102944.0 145668.0 164038.0 136742.0 125807.0 121892.0 106484.0 177805.0 118500.0 True False 76563.39729688303 102705.63949286068 133691.73933474114 176101.90173472656 128699.10440511562 120426.52788044098 128202.97133786343 111431.63537895365 157778.72853034397 138982.5671086755 0.5508848979384252 0.7389821733005653 0.961931716444716 1.2670790689671614 0.9260089742368994 0.8664865701197987 0.9224392238892587 0.8017669963731583 1.1352411443585662 1.0 17.084544408298342 -5.055121991260938 2.7274221895468784 0.9795076478733645 0.5592973302902176 0.559126998842065 0.12611545826910092 0.2349041274700278 3.1843618712893695 0.03526547032562457 0.16655803751830267 8.808014253117864e-06 5.055121991260938 -0.420210317583147 SYS(ph)CSSPK ddPTM_PC-9_AZD4547_30min_R2 2 SYSCSSPK 8 0 Q8N1W1-5;Q8N1W1-4;Q8N1W1-3;Q8N1W1;Q8N1W1-6;Q8N1W1-2 Q8N1W1-5 ARHGEF28 Rho guanine nucleotide exchange factor 28 1 S(0.128)YS(0.831)CS(0.03)S(0.011)PK;S(0.011)YS(0.817)CS(0.151)S(0.021)PK 96.171 0.006201600000000001 27188000.0 56159.0 52095.0 66812.0 89070.0 78333.0 70629.0 66107.0 68776.0 64553.0 68413.0 True False 74016.39382023434 68933.68997675071 65926.02922581477 68536.2876177822 67457.8150760031 66212.55746475741 71990.39493377192 58148.24951525481 67965.13979243854 66017.88169329645 1.121156752106908 1.0441669470250563 0.9986086729061012 1.0381473300852893 1.0218112630362215 1.002948833959341 1.0904681139001455 0.8807954454733627 1.029495919123679 1.0 16.01056922729491 -1.5228788484494222 0.8242760880598126 1.0038290635893239 35.43111145671085 0.32272500059653797 0.049825434362605545 686.7276708683222 2.1531262300798466 0.017216902565519197 44241.755494562836 0.029999992873332954 1.5228788484494222 34.42728239312153 SYS(ph)CSSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SYSCSSPK 8 0 Q8N1W1-5;Q8N1W1-4;Q8N1W1-3;Q8N1W1;Q8N1W1-6;Q8N1W1-2 Q8N1W1-5 ARHGEF28 Rho guanine nucleotide exchange factor 28 1 S(0.001)YS(0.815)CS(0.155)S(0.029)PK;S(0.002)YS(0.938)CS(0.059)SPK 74.944 0.02707 17700900.0 30554.0 34839.0 25695.0 31723.0 42587.0 43286.0 43576.0 51582.0 39977.0 36337.0 True False 35726.18873099241 38297.58567707018 26307.66624883015 29945.663157353658 34242.383063337445 41016.00595935204 39448.16581708044 50228.027155646625 40561.58799594638 42924.610456466275 0.8323008258217176 0.8922057828785941 0.6128807220163625 0.6976338943768461 0.7977331115926082 0.9555358924212038 0.9190104557172017 1.1701452062468314 0.9449494722167263 1.0 15.38951742128823 -6.897099215983797 1.8642129943405141 1.0262839029389166 0.755815639691211 0.6106278149293751 0.0933458850418047 0.23670340603702186 1.6823473750112767 0.04240771944546561 0.03515862044312329 1.2673622997526258e-07 6.897099215983797 -0.27046826324770556 SYS(ph)CSSPK ddPTM_PC-9_Lapatinib_30min_R1 3 SYSCSSPK 8 0 Q8N1W1-5;Q8N1W1-4;Q8N1W1-3;Q8N1W1;Q8N1W1-6;Q8N1W1-2 Q8N1W1-5 ARHGEF28 Rho guanine nucleotide exchange factor 28 1 S(0.251)YS(0.733)CS(0.016)SPK;S(0.001)YS(0.99)CS(0.009)SPK;S(0.028)YS(0.823)CS(0.149)S(0.001)PK 101.97 0.0044214 39831000.0 54365.0 65633.0 66780.0 58698.0 73736.0 103723.0 103913.0 80865.0 115104.0 85419.0 True False 53589.745130680014 65481.030820979555 61289.60617825456 63014.84673078789 69398.99345055364 99287.00908012252 109293.10668978604 84622.28311219643 102139.77542114523 100183.56033633703 0.5349155585084828 0.6536105385069778 0.6117730890426794 0.6289938840188346 0.6927183783204229 0.9910509144094639 1.0909285547735215 0.8446723477195444 1.019526308290909 1.0 16.612286262739453 -6.688553958977559 3.741733705732081 0.98784228617628 0.6158367451998165 0.8911510294211251 0.06420737333568668 0.07208545003540916 1.992208404795647 0.022464389588969406 0.021904550626731974 2.0485475120782564e-07 6.688553958977559 -0.37200554097646354 SYS(ph)EPEKMNEVGIVEEAEPAPLGPQR ddPTM_PC-9_AZD4547_30min_R2 1 SYSEPEKMNEVGIVEEAEPAPLGPQR 26 1 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 S(0.071)Y(0.059)S(0.87)EPEKMNEVGIVEEAEPAPLGPQR 77.584 2.7463e-05 3665800.0 11266.0 9355.8 17296.0 20553.0 18268.0 17385.0 15464.0 15025.0 13629.0 18216.0 True False 14848.35365264268 12379.879387359344 17066.643738994353 15814.823390684584 15731.803528633181 16297.91320172743 16840.2660422625 12703.231490152122 14349.401115845043 17578.26338451888 0.8446996911947273 0.7042720385144681 0.9708947559646246 0.8996806478968024 0.8949577773699836 0.9271628741256062 0.9580164817130724 0.7226670355468572 0.8163150592272109 1.0 14.101504928398388 -5.258817535910687 24.999867355699898 0.8918417392901269 0.774485868624049 0.2638682801113632 0.08235882400669042 328.2693175821715 3130074.200157358 0.021815820261946006 0.052593890843682954 5.510391608711006e-06 5.258817535910687 -0.11735587066607789 SYS(ph)EPEKMNEVGIVEEAEPAPLGPQR ddPTM_PC-9_Lapatinib_30min_R1 1 SYSEPEKMNEVGIVEEAEPAPLGPQR 26 1 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 S(0.164)Y(0.032)S(0.804)EPEKMNEVGIVEEAEPAPLGPQR 125.59 4.5475e-11 2757600.0 8263.0 7902.5 5667.7 7842.4 8491.5 7114.5 6609.2 7097.6 6047.3 6077.4 True False 8145.168104751383 7884.202246778156 5201.72358395468 8419.156257479486 7992.046664931335 6810.2294197095225 6951.39203693603 7427.380407062688 5366.1893931078985 7127.870492373528 1.1427211133348052 1.1061090763663377 0.7297724600243887 1.1811601047588576 1.1212390395535992 0.9554367502883413 0.9752410687559039 1.0420195505810075 0.7528460847948147 1.0 12.799255409161116 -8.229082516298334 24.48402400417337 0.8764229490000967 1.0276685518074697 0.17670149073752828 0.13385131661164384 775.738146932141 586992.9749178197 0.08973820052676353 0.03391093129573956 5.900889521478966e-09 8.229082516298334 0.1512456028073731 SYS(ph)FIAR ddPTM_PC-9_AZD4547_30min_R2 1 SYSFIAR 7 0 J3QK89;Q8IWX8 J3QK89 CHERP Calcium homeostasis endoplasmic reticulum protein 1 S(0.144)Y(0.003)S(0.853)FIAR 69.825 0.04556 3047400.0 12640.0 14637.0 20035.0 26817.0 23300.0 24369.0 17018.0 22685.0 18040.0 18277.0 True False 16659.257071667278 19368.1240078645 19769.32280936355 20634.754968519843 20065.19718727574 22845.202577675922 18532.569031765597 19179.554499441005 18993.55757061007 17637.127793085838 0.9445561242799461 1.0981450174363 1.1208924174781782 1.1699611870255395 1.1376680728673838 1.2952904149524715 1.0507702415713511 1.0874533951588101 1.076907634476402 1.0 14.106328016632212 -8.460063299641345 1.208415665505726 1.004142247423925 1.1244417547354533 0.14828294763107308 0.08363961350792695 0.9098219232366832 2.8982691413267623 0.08244531489504489 0.02590952649532011 3.466863162648957e-09 8.460063299641345 0.12029950731152828 SYS(ph)FIAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SYSFIAR 7 0 J3QK89;Q8IWX8 J3QK89 CHERP Calcium homeostasis endoplasmic reticulum protein 1 S(0.033)YS(0.967)FIAR 71.692 0.040763 1978400.0 10377.0 7819.6 11207.0 8279.5 10279.0 17421.0 14120.0 20386.0 14388.0 11757.0 True False 12133.621144907636 8595.87821006395 11474.217382784174 7815.626457501167 8264.903738418905 16507.41209208223 12782.451380052677 19850.88910075245 14598.397280578247 13888.451031639202 0.8736482648256527 0.6189227431109292 0.8261696971566392 0.562742845814586 0.5950918298657405 1.1885711411932682 0.920365514551122 1.4293090752547026 1.051117741447316 1.0 13.761598085162163 -6.76457087692192 24.99849414838696 1.1323603677082021 0.690975611759105 0.6470444064835013 0.15584462555195586 48.979914568481846 390999.46206394996 0.05224446366969822 0.048017801840750975 1.7196066782794855e-07 6.76457087692192 -0.4413847559490971 SYS(ph)FPKPGHR ddPTM_PC-9_Lapatinib_30min_R1 1 SYSFPKPGHR 10 1 P43405 P43405 SYK Tyrosine-protein kinase SYK 1 S(0.054)Y(0.002)S(0.943)FPKPGHR 58.781000000000006 0.035584 7614600.0 28104.0 35569.0 36393.0 41054.0 36967.0 31108.0 30314.0 31242.0 36067.0 37061.0 True False 27703.231806357613 35486.642165852834 33400.90802104254 44073.2481121293 34792.673739918355 29777.58335628982 31883.510592458853 32693.617374528352 32004.7546576526 43466.944469321614 0.63734021667684 0.8164052614947165 0.7684208869251542 1.0139486142909264 0.8004398322609163 0.6850627234059766 0.7335116599916934 0.7521489668454397 0.7363009994926404 1.0 15.407631063757773 -6.536069803426232 24.689499006130227 0.7606797862999292 0.8192224776870005 0.0 0.1174672190774914 696.186078461408 1303030.4985043919 0.03822234457283332 0.03824267615298513 2.9102493209640857e-07 6.536069803426232 0.058542691387071355 SYS(ph)HDVLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SYSHDVLPK 9 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 S(0.002)YS(0.998)HDVLPK 84.198 0.013393 5986700.0 30664.0 25391.0 48506.0 37225.0 55951.0 52091.0 52243.0 56459.0 45777.0 48609.0 True False 35854.80955839336 27911.65067672691 49662.567000029405 35139.40393507831 44987.80319761416 49359.25625903538 47294.164833434304 54977.011073255264 46446.402023424445 57421.42691136772 0.6244151614994992 0.4860842402925595 0.8648786641384857 0.6119562996809083 0.7834671762346596 0.8595964766814899 0.8236326991043734 0.9574302491318177 0.8088688233943808 1.0 15.8093015612331 -4.00844321978925 0.2115505544363496 1.0071484710536094 6.673803780202072e-12 0.6245622370609947 0.09392193826573599 11.3188973289181 0.3483929886947755 0.16655231518296398 3.147934743636486 9.807465299840394e-05 4.00844321978925 -1.0071484710469356 SYS(ph)LSELSVLQAK ddPTM_PC-9_AZD4547_30min_R2 2 SYSLSELSVLQAK 13 0 Q9P0V3;Q9P0V3-2 Q9P0V3 SH3BP4 SH3 domain-binding protein 4 1 S(0.089)YS(0.86)LS(0.036)ELS(0.015)VLQAK;S(0.197)YS(0.803)LSELSVLQAK 169.04 0.00022586 176843400.0 71868.72 52612.6 66045.6 90769.9 87841.2 67832.1 78065.5 106444.3 70083.5 85920.3 True False 94721.47799775933 69618.59405453122 65169.79219057163 69844.30193597531 75645.96562948173 63590.5480638996 85013.17826708777 89995.77928167721 73787.97073169907 82912.25644910404 1.142430348110287 0.8396658954429351 0.7860091496915937 0.8423881453383127 0.9123616805184557 0.7669619762783186 1.025339098318635 1.0854339652053906 0.8899525099403616 1.0 16.339297762468767 -7.290464715472737 24.82069930710611 1.0073009155265626 0.8749943721600629 0.22422338941063746 0.1072721136576208 943.2904732761958 806640.4679405836 0.04472444168172696 0.03015882618778255 5.1231289175558285e-08 7.290464715472737 -0.13230654336649972 SYS(ph)LSELSVLQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SYSLSELSVLQAK 13 0 Q9P0V3;Q9P0V3-2 Q9P0V3 SH3BP4 SH3 domain-binding protein 4 1 S(0.023)YS(0.939)LS(0.038)ELSVLQAK;S(0.152)YS(0.493)LS(0.356)ELSVLQAK 178.84 0.00011873 19949900.0 38982.0 38424.0 42298.0 47292.0 62015.0 52925.0 51484.0 55814.0 47920.0 43122.0 True False 45580.88267040469 42238.48078463056 43306.54473605828 44642.38256273267 49863.60592840239 50149.5198308623 46607.06280811839 54348.94163982131 48620.739344266716 50939.677246435815 0.8948011674650711 0.8291862663418413 0.8501534967830677 0.876377412969499 0.9788755764425516 0.984488370200092 0.914946174131471 1.0669274832051283 0.95447678455145 1.0 15.636502198281274 -6.2219250487817455 3.486745689265139 0.9843619176889468 0.8560358402996596 0.7000814150004919 0.038814913837730745 0.1320327192940939 3.3405274702554886 0.01182666838821583 0.015101421021152677 5.998945980665577e-07 6.2219250487817455 -0.12832607738928714 SYS(ph)LSELSVLQAK ddPTM_PC-9_Lapatinib_30min_R1 2 SYSLSELSVLQAK 13 0 Q9P0V3;Q9P0V3-2 Q9P0V3 SH3BP4 SH3 domain-binding protein 4 1 SYS(0.5)LS(0.5)ELSVLQAK;S(0.003)YS(0.864)LS(0.133)ELSVLQAK 230.69 5.1274000000000006e-20 261270000.0 327950.0 278290.0 266970.0 247020.0 262180.0 233080.0 212113.0 210530.0 271500.0 232570.0 True False 323273.3728613364 277645.63660308596 245020.75713400118 265186.6748345637 246759.08786571218 223111.71173601772 223095.17326312017 220311.9923775513 240920.81097825363 272769.4146199547 1.1851525703926449 1.0178767182894213 0.8982706417997219 0.9722009163089054 0.9046435364079133 0.8179498865254953 0.8178892548270309 0.8076858348818489 0.8832398284606974 1.0 18.057322359818357 -1.5228874946106576 0.6088319773753946 0.858678351393823 23.018235582006426 0.7106823202819721 0.059756958741200475 90.79490802324821 0.6818298033415239 0.026642187316773883 2683.435628374792 0.029999395623760864 1.5228874946106576 22.159557230612602 SYS(ph)PAHNR ddPTM_PC-9_AZD4547_30min_R2 1 SYSPAHNR 8 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 S(0.057)YS(0.943)PAHNR 75.387 0.014986000000000001 50160000.0 8018.7 6218.9 13281.0 19468.0 16504.0 13241.0 10785.0 13373.0 9318.1 13999.0 True False 10568.479800678666 8229.037807782232 13104.88526234875 14979.953377601696 14212.704479776768 12413.0381768233 11744.844106686574 11306.510130968685 9810.635742721826 13508.899270963975 0.7823346365010326 0.6091567967694987 0.97009275141435 1.1088951865826406 1.0520993749894598 0.9188785798043428 0.8694153291919897 0.8369675355616053 0.7262350207769188 1.0 13.721622505655159 -5.26932253025339 24.81813699283735 0.9369288399194257 0.6957457127894126 0.42905636293725746 0.1105340786775282 490.3553262929684 1543765.6204253815 0.03206930861621723 0.06880915068340623 5.37870183057522e-06 5.26932253025339 -0.2411831271300131 SYS(ph)PDGK ddPTM_PC-9_AZD4547_30min_R2 2 SYSPDGK 7 0 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2 A0A0R4J2E8 MATR3 Matrin-3 1 S(0.001)YS(0.999)PDGK;S(0.001)YS(0.999)PDGK 122.52 0.0051521 713840000.0 323500.0 360690.0 358900.0 378490.0 393520.0 450000.0 422790.0 431070.0 427350.0 386150.0 True False 426366.2707819913 477275.9888226176 354140.7514989061 291234.97811220796 338886.5406496453 421861.4288626607 460417.49094724207 364458.036503153 449938.84854768374 372631.0060349116 1.1442050282365532 1.280827362975538 0.9503791841351142 0.7815639960055345 0.9094426796515565 1.132115744611807 1.2355855618308524 0.9780668559529561 1.2074648680886453 1.0 18.50738819807681 -6.802684751687863 24.954876676116832 1.1170845776998042 1.0117789776021722 0.09944321085717689 0.14582080242166276 386.46080730281227 233819.34588287788 0.0569434478567245 0.05021991845797748 1.5751258114671596e-07 6.802684751687863 -0.10530560009763201 SYS(ph)PDGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SYSPDGK 7 0 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2 A0A0R4J2E8 MATR3 Matrin-3 1 SYS(1)PDGK;S(0.002)YS(0.998)PDGK;S(0.223)YS(0.777)PDGK;S(0.011)YS(0.989)PDGK 104.2 0.010385 580042000.0 1638670.0 2213242.0 1771919.0 1810828.0 2019794.0 1484870.0 1882621.0 1403127.0 1375285.0 1407921.0 True False 1916064.4657922168 2432958.038953183 1814168.2690002264 1709373.1779435892 1624029.8649125502 1407000.8032357586 1704285.5098842855 1366296.402985944 1395395.941341402 1663165.9322034996 1.1520585100331249 1.4628474476565303 1.0907921055096808 1.0277827033643423 0.9764689340172459 0.8459774073003333 1.024723677225824 0.8215033608677648 0.8389998341853157 1.0 20.665500681199447 -5.687029370218667 1.6836214593486567 0.9120672423796208 1.3094959748833461 0.6788089249795366 0.10188969750879491 0.19904530963804723 1.1346766915641515 0.03061074278116963 0.07173384816790256 2.0557515660927117e-06 5.687029370218667 0.39742873250372535 SYS(ph)PDGK ddPTM_PC-9_Lapatinib_30min_R1 5 SYSPDGK 7 0 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2 A0A0R4J2E8 MATR3 Matrin-3 1 S(0.001)YS(0.999)PDGK;S(0.018)YS(0.982)PDGK;S(0.005)YS(0.995)PDGK;S(0.002)YS(0.998)PDGK;S(0.028)YS(0.972)PDGK 93.598 0.013808 316133300.0 209705.0 294800.0 269912.0 274228.0 325801.0 256820.0 282322.0 326388.0 292000.0 273208.0 True False 206714.56824481313 294117.4087124575 247720.87725045005 294395.6419177916 306638.02572941093 245836.4072766602 296939.25174784503 341553.1780179754 259111.88510368383 320431.6387732229 0.6451128516404397 0.9178788019762661 0.7730849494102797 0.9187471095079423 0.9569530240627266 0.7672039135019513 0.9266851827886946 1.065915898085522 0.8086338979998896 1.0 18.289657078012716 -4.014014665624259 0.9302685851989765 0.9145730924977734 3.052039665267505e-76 0.38559063407369787 0.09418576077111322 8.385930604698443 2.0384115839757415 0.030719659762765215 10.909105788829986 9.682451591857686e-05 4.014014665624259 -0.9145730924977734 SYS(ph)PDGKESPSDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 SYSPDGKESPSDK 13 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2 A0A0R4J2E8 MATR3 Matrin-3 1 S(0.225)YS(0.775)PDGKESPSDK;S(0.062)YS(0.938)PDGKESPSDK;S(0.028)YS(0.963)PDGKES(0.007)PS(0.001)DK 155.09 0.00086717 28350900.0 54770.0 24384.5 32462.1 65928.0 56095.0 57650.0 55210.0 63393.0 57793.0 40962.6 True False 64041.47924319086 26805.23200845367 33236.11957719982 62234.26790145994 45103.58743132683 54626.73251297519 49980.10911421449 61729.0009204356 58638.11329138582 48388.79512023679 1.3234774514236234 0.5539553514785366 0.6868556965432698 1.2861297279012596 0.9321080907109413 1.1289128480516684 1.0328860016047845 1.2756879101257013 1.2118118077890028 1.0 15.562385396141707 -5.758591951592453 24.998175322092308 1.1238418338881315 0.8246820853188851 0.24576218188130095 0.21415338073704066 93.95138094500734 824799.7617135064 0.057619367409947685 0.09440553096519878 1.7434441852836982e-06 5.758591951592453 -0.29915974856924643 SYS(ph)PDGKESPSDK ddPTM_PC-9_Lapatinib_30min_R1 1 SYSPDGKESPSDK 13 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2 A0A0R4J2E8 MATR3 Matrin-3 1 S(0.21)YS(0.789)PDGKES(0.001)PSDK 162.7 0.0016077 13112000.0 44835.0 27918.0 31954.0 36211.0 33725.0 27092.0 24997.0 28041.0 31457.0 22747.0 True False 44195.644678268 27853.357586276823 29326.865466007028 38874.077736354906 31741.361805901084 25933.338314536577 26291.22234873965 29343.887228703334 27913.981403104717 26678.78864152773 1.656583635490625 1.044026322204179 1.099257760914877 1.4571155481866296 1.1897602335847077 0.9720583143032664 0.9854728676779274 1.0998957869858887 1.0462986823792406 1.0 14.703405541554117 -6.5906727084225665 5.037367169401759 1.0266640541606802 1.284721873426194 0.4094059328064973 0.1649281448521394 0.23321939992404947 11.343842535777709 0.055138704872629354 0.05542187323065046 2.566417402950261e-07 6.5906727084225665 0.25805781926551385 SYS(ph)PDGKESPSDKK ddPTM_PC-9_AZD4547_30min_R2 2 SYSPDGKESPSDKK 14 2 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2 A0A0R4J2E8 MATR3 Matrin-3 1 S(0.112)Y(0.004)S(0.884)PDGKESPSDKK;S(0.112)YS(0.887)PDGKESPSDKK 99.238 0.0063405 168512000.0 74852.0 51762.0 66655.0 115716.0 94238.0 71009.0 71847.0 65868.0 66263.0 88647.0 True False 98653.37898168022 68493.05423892075 65771.11114839675 89039.46399437828 81154.68036628712 66568.79600468594 78241.24381391847 55689.6140960626 69765.52690140432 85543.4955120469 1.153254007112523 0.8006810316662245 0.7688616271138272 1.0408677300524745 0.9486949285917162 0.7781865307960347 0.9146369732214173 0.6510093346398261 0.815556185584904 1.0 16.384370539941862 -6.755677489108364 24.79085183801011 0.8152383328687576 0.9304160343876371 0.13822119632826957 0.1332225707095301 253.2201149207032 1089492.3968488723 0.04439942736174436 0.04324219670054962 1.7551834326104645e-07 6.755677489108364 0.11517770151887952 SYS(ph)PDGKESPSDKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SYSPDGKESPSDKK 14 2 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2 A0A0R4J2E8 MATR3 Matrin-3 1 S(0.01)YS(0.989)PDGKESPSDKK;S(0.023)YS(0.973)PDGKES(0.001)PS(0.003)DKK 112.34 0.00088213 145287000.0 198047.0 109487.0 146525.0 307190.0 264770.0 301040.0 288250.0 344920.0 304450.0 224020.0 True False 231572.44549344893 120356.14578562471 150018.71169915725 289979.1402234175 212890.21916734878 285252.93244936777 260944.87325072184 335866.2154729483 308902.00528718735 264633.0526586564 0.8750700003908752 0.45480390516776875 0.5668933271637185 1.095778238243937 0.8044732773496386 1.0779187617856205 0.9860630432560069 1.2691771194060697 1.1672842911487418 1.0 18.01363373986552 -6.171968271787585 0.9140767721226176 1.1273516715132705 0.6090686090175786 0.5431469523624406 0.16627662258362486 0.442683548951941 0.777737840774099 0.07940433200608267 0.1431527498347631 6.730258236745976e-07 6.171968271787585 -0.5182830624956919 SYS(ph)PDGKESPSDKK ddPTM_PC-9_Lapatinib_30min_R1 2 SYSPDGKESPSDKK 14 2 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2 A0A0R4J2E8 MATR3 Matrin-3 1 S(0.411)Y(0.001)S(0.588)PDGKESPSDKK;S(0.028)YS(0.972)PDGKESPSDKK 81.346 0.029601 365398000.0 66622.0 52119.0 33918.0 47008.0 33895.0 33217.0 25551.8 28310.0 37447.0 27125.0 True False 65671.95806302143 51998.321657681845 31129.392967266253 50465.12513409105 31901.362740133965 31796.386342608937 26874.74717808241 29625.385950736112 33229.32452560838 31813.520108209395 2.064278264072857 1.6344724343869075 0.9784957106721867 1.586279197097358 1.0027611729738106 0.9994614313178114 0.844758677652507 0.9312199923167684 1.0445032304687856 1.0 14.957352391844559 -1.5228787464728832 0.49314568054445695 0.9473397994160827 35.527135693341826 0.7769306827844991 0.1813918574229924 46.93706553738556 0.5081487969505224 0.10144155467705247 1675.546326208591 0.029999999917621863 1.5228787464728832 34.57979589392574 up SYS(ph)PDHR ddPTM_PC-9_Lapatinib_30min_R1 3 SYSPDHR 7 0 A0A024RAC6;Q14241 A0A024RAC6 TCEB3 Transcription elongation factor B polypeptide 3 1 S(0.221)Y(0.005)S(0.774)PDHR;S(0.002)YS(0.998)PDHR;S(0.182)YS(0.818)PDHR 98.62899999999999 0.012101 64997000.0 129199.0 115640.0 154698.0 93745.0 116001.0 125069.0 120622.0 136619.0 129481.0 82692.0 True False 127356.59856780505 115372.24268490027 141979.3275915489 100639.3200241528 109178.04924674072 119720.09042007885 126867.21695202126 142966.81749218024 114897.4862846236 96985.20201983608 1.3131549547296628 1.1895860428408813 1.46392773984747 1.0376770675135507 1.125718635141997 1.2344160544780107 1.3081090136418285 1.4741096014105295 1.1846909001759256 1.0 16.56547701755823 -5.751392282831865 24.999833498743282 1.2181881988800396 1.308959117796173 0.12821270045581246 0.14212346490884972 614.0607473034436 1527930.2269622618 0.040333140590470794 0.06882798692162972 1.7725876418879513e-06 5.751392282831865 0.09077091891613343 SYS(ph)PSFQR ddPTM_PC-9_Lapatinib_30min_R1 1 SYSPSFQR 8 0 Q9P227;Q9P227-2 Q9P227 ARHGAP23 Rho GTPase-activating protein 23 1 S(0.002)YS(0.945)PS(0.053)FQR 79.48899999999999 0.020640000000000002 8738000.0 56775.0 46758.0 90849.0 43383.0 56618.0 66334.0 45444.0 45982.0 70459.0 47742.0 True False 55965.37808874012 46649.73472380294 83379.74590728135 46573.5305414455 53287.840555270785 63497.04945210651 47796.86796080027 48118.491585543896 62523.16545383718 55994.14108778376 0.9994863212742464 0.8331181408902888 1.4890798267012315 0.8317572095343104 0.9516681481323157 1.1339945254729455 0.8536048063647879 0.8593486863225035 1.1166019201154933 1.0 15.772988259116094 SYS(ph)SPDITQAIQEEEK ddPTM_PC-9_AZD4547_30min_R2 3 SYSSPDITQAIQEEEK 16 0 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 S(0.001)YS(0.5)S(0.5)PDITQAIQEEEK;SYS(0.791)S(0.209)PDITQAIQEEEK;S(0.003)YS(0.95)S(0.048)PDITQAIQEEEK 254.53 2.8954999999999995e-57 22034600.0 40786.7 41528.7 51651.8 72674.0 57992.0 52284.9 45301.4 54445.4 49089.2 52371.2 True False 53756.02218393762 54952.040137009106 50966.86338331339 55920.13210210732 49940.81181478519 49015.51693764733 49333.13683955967 46032.11446082722 51683.95489441197 50537.70022855264 1.0636816068168986 1.0873474631511322 1.0084919407258324 1.1065033004907836 0.9881892446417612 0.9698802421950077 0.9761650533454149 0.910847036027574 1.0226811798058772 1.0 15.625072393963663 -6.403166862046852 5.609887528189964 0.9712522391294395 1.063500631858338 0.5974825024907415 0.03554440888583484 0.1517178573778998 6.377250722064433 0.01064404903746727 0.012056886533623874 3.952147438315446e-07 6.403166862046852 0.09224839272889851 SYS(ph)SPDITQAIQEEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 SYSSPDITQAIQEEEK 16 0 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 S(0.006)YS(0.833)S(0.161)PDITQAIQEEEK;S(0.039)YS(0.941)S(0.021)PDITQAIQEEEK;SYS(0.98)S(0.02)PDITQAIQEEEK;SYS(0.968)S(0.032)PDITQAIQEEEK 311.95 4.3965999999999995e-130 35921800.0 85514.0 88373.0 85422.0 100485.0 115434.0 90982.0 100758.0 95976.0 96182.0 74312.0 True False 99989.83122151229 97146.08740318952 87458.78444473914 94855.1512267654 92815.53634990234 86210.74375534267 91213.47281525136 93456.73169497783 97588.47979153309 87784.17734653184 1.1390416159713852 1.1066468962817881 0.9962932625032391 1.080549526053204 1.0573151011429884 0.9820761139564141 1.0390650749642754 1.0646193257134864 1.1116864421511674 1.0 16.421673304266598 -5.066010436255965 5.775848747833765 1.0436266517634605 1.1320075086124803 0.4292829384583631 0.03827066468929006 0.18117823085098242 11.659256517745263 0.009911936651112905 0.028266924596277138 8.589928793428827e-06 5.066010436255965 0.08838085684901986 SYS(ph)SPDITQAIQEEEK ddPTM_PC-9_Lapatinib_30min_R1 4 SYSSPDITQAIQEEEK 16 0 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 S(0.001)YS(0.875)S(0.123)PDITQAIQEEEK;S(0.009)YS(0.988)S(0.002)PDITQAIQEEEK;SYS(0.995)S(0.005)PDITQAIQEEEK;S(0.237)Y(0.001)S(0.635)S(0.127)PDITQAIQEEEK 339.81 9.980299999999994e-190 35562000.0 95054.7 73206.29999999999 77010.6 81311.8 74068.7 69247.8 66738.1 68768.7 78281.09999999999 54735.0 True False 93699.20254710311 73036.79531013167 70679.08573751253 87291.74102021329 69712.12469066709 66286.23301850607 70193.4722659688 71963.94485448212 69464.25818147253 64195.87182019695 1.459582990157694 1.1377179441490697 1.100991134375028 1.3597718754362338 1.0859284672684302 1.0325622370884517 1.0934265751942778 1.1210058032398467 1.082067369939792 1.0 15.970192905930993 -2.357034586018225 1.2750421478595357 1.111143061662873 199.9989773115418 0.559360942100813 0.09183081490876548 679.9440831779721 2.5426466798346974 0.027601778752437668 393943.73579167033 0.004395066129460839 2.357034586018225 198.88783424987892 SYS(ph)SPDITQAIQEEEKR ddPTM_PC-9_AZD4547_30min_R2 6 SYSSPDITQAIQEEEKR 17 1 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 S(0.008)YS(0.911)S(0.081)PDITQAIQEEEKR;S(0.017)Y(0.001)S(0.933)S(0.049)PDITQAIQEEEKR;S(0.134)YS(0.837)S(0.03)PDITQAIQEEEKR;S(0.008)YS(0.766)S(0.225)PDITQAIQEEEKR;S(0.043)YS(0.941)S(0.015)PDITQAIQEEEKR;S(0.193)Y(0.002)S(0.768)S(0.037)PDITQAIQEEEKR 148.44 3.2994e-05 519885300.0 180048.3 163845.4 210717.3 256615.0 236420.8 217791.1 204298.8 243878.0 183800.1 218245.7 True False 237299.91416271162 216805.22137857246 207923.05092176213 197456.37641222804 203597.85284006398 204172.58808793416 222480.9974207822 206192.25885892296 193515.39805065875 210604.98447182085 1.126753551241151 1.029440124232108 0.9872655741895912 0.9375674412808017 0.9667285574967271 0.969457530171859 1.056389989908099 0.9790473828339599 0.9188547865378338 1.0 17.684180056041086 -4.796134822363464 1.966571066637142 0.9767720422486251 1.1688191911147379 0.6376418888315044 0.03466129610466983 0.5001234112667325 2.153920235536004 0.00988680281415614 0.175024232306482 1.599061538946452e-05 4.796134822363464 0.19204714886611274 SYS(ph)SPDITQAIQEEEKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 SYSSPDITQAIQEEEKR 17 1 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 S(0.175)Y(0.002)S(0.81)S(0.012)PDITQAIQEEEKR;S(0.213)Y(0.014)S(0.758)S(0.014)PDITQAIQEEEKR;S(0.047)YS(0.894)S(0.058)PDITQAIQEEEKR;S(0.087)Y(0.003)S(0.779)S(0.131)PDITQAIQEEEKR;S(0.045)YS(0.953)S(0.002)PDITQAIQEEEKR;S(0.284)YS(0.69)S(0.026)PDITQAIQEEEKR 167.97 9.1609e-06 320753000.0 134159.0 137365.8 124643.2 162375.6 159493.3 143025.9 151732.8 140768.1 134697.3 118332.5 True False 156869.46893896777 151002.56880505447 127615.16659996864 153278.22156079815 128241.73279723372 135525.37002129303 137359.5707336582 137073.08653113036 136666.99319024384 139785.24553044527 1.1222176442420138 1.0802468331478237 0.9129373140613328 1.0965264680056244 0.9174196626446003 0.9695255712218609 0.9826471328387891 0.9805976733165004 0.9776925502518627 1.0 17.092852565311766 -5.084427559855187 5.677621008805489 0.9808955729440131 1.1129279154145975 0.5180246142104483 0.04761468715715055 0.146437895060385 7.494779653705205 0.011455810379662212 0.032354388689178754 8.233271561070017e-06 5.084427559855187 0.13203234247058437 SYS(ph)SPDITQAIQEEEKR ddPTM_PC-9_Lapatinib_30min_R1 6 SYSSPDITQAIQEEEKR 17 1 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 S(0.152)Y(0.053)S(0.759)S(0.036)PDIT(0.001)QAIQEEEKR;S(0.2)Y(0.002)S(0.784)S(0.014)PDITQAIQEEEKR;S(0.032)YS(0.963)S(0.005)PDITQAIQEEEKR;S(0.061)Y(0.001)S(0.931)S(0.006)PDITQAIQEEEKR;S(0.186)YS(0.813)S(0.001)PDITQAIQEEEKR;S(0.001)YS(0.712)S(0.286)PDITQAIQEEEKR 179.85 1.0845e-06 486943800.0 224634.1 184729.9 189199.7 197315.8 192853.5 190494.1 192172.7 190173.3 210093.7 158540.9 True False 221430.77654115166 184302.16926632155 173644.43099796207 211827.0621582129 181510.2362945693 182347.11140643578 202122.46209775718 199009.4457797644 186430.73512125982 185944.48332252988 1.1908434850259528 0.9911677183056856 0.9338509424706473 1.1391951961854572 0.9761528443935109 0.9806535162979034 1.0870043492883077 1.0702627054257519 1.002615037510344 1.0 17.504512420551322 -4.754818258638361 24.999214697852135 1.0228070749077076 1.1908437685937678 0.4370214212420248 0.058064785134692 224.48925094696753 847522.0130229185 0.014499663193572727 0.1362993157989873 1.7586594149017015e-05 4.754818258638361 0.16803669368606022 SYS(ph)VVASEYDK ddPTM_PC-9_Lapatinib_30min_R1 1 SYSVVASEYDK 11 0 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 S(0.002)YS(0.972)VVAS(0.026)EYDK 103.43 0.007264699999999999 0.0 22215.0 25039.0 19659.0 16296.0 26400.0 22565.0 24451.0 22405.0 22422.0 16596.0 True False 21898.21002626795 24981.02373389156 18042.712905934535 17494.4622018624 24847.203904396996 21599.947551584144 25716.953140338173 23446.018093473787 19896.598245872596 19464.59648722004 1.1250276901782044 1.283408250990123 0.926950266746137 0.8987837078127369 1.2765332135557519 1.109704358154361 1.3212168645377917 1.2045468350123698 1.0221942314055263 1.0 14.248564816609644 -6.284435670175308 24.970484807086656 1.1719027124121377 1.0652048201520836 0.099987716850234 0.13716470115506244 1801.21572696735 1955841.7688265562 0.04420463386924956 0.05015356585735098 5.194746149313807e-07 6.284435670175308 -0.1066978922600541 SYSCS(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 1 SYSCSSPK 8 0 Q8N1W1-5;Q8N1W1-4;Q8N1W1-3;Q8N1W1;Q8N1W1-6;Q8N1W1-2 Q8N1W1-5 ARHGEF28 Rho guanine nucleotide exchange factor 28 1 S(0.009)YS(0.367)CS(0.62)S(0.003)PK 109.83 0.0037717 13282000.0 21415.0 21663.0 35973.0 30686.0 31118.0 29934.0 27279.0 31302.0 27793.0 27936.0 True False 28224.524540328675 28665.141106946 35495.974515659356 23611.81679397397 26797.802835778813 28062.222247944144 29706.7781535747 26464.995148402115 29262.08123946596 26957.969143056638 1.0469825968918824 1.0633271725637043 1.3167154516460224 0.8758752066475856 0.9940586656796038 1.0409620286686885 1.1019664721749285 0.9817132369267699 1.0854705369006914 1.0 14.718424195891206 -5.77459498718087 24.998299838167547 1.0149516585825273 1.134440356829067 0.3079451790225791 0.08958705540395306 299.76735223006386 569617.4487191859 0.025477996814502763 0.038043400213852524 1.68037036151804e-06 5.77459498718087 0.11948869824653974 SYSCS(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SYSCSSPK 8 0 Q8N1W1-5;Q8N1W1-4;Q8N1W1-3;Q8N1W1;Q8N1W1-6;Q8N1W1-2 Q8N1W1-5 ARHGEF28 Rho guanine nucleotide exchange factor 28 1 S(0.03)YS(0.038)CS(0.908)S(0.024)PK 95.775 0.0063234 12461000.0 20012.0 13875.0 13869.0 18817.0 24995.0 25104.0 27448.0 30526.0 24010.0 23363.0 True False 23399.636344983315 15252.418303319511 14199.689558475404 17762.7444955371 20097.409178108825 23787.502046933732 24847.926733688815 29724.724844970537 24361.100827542654 27598.526958593768 0.8478581621435785 0.5526533472675119 0.5145089656335384 0.6436120493744703 0.7282058643296827 0.8619120173559358 0.9003352523476454 1.0770402670246393 0.8826956911175642 1.0 14.752303646326641 -6.822521319496058 1.4844162691074867 0.9783683981102269 0.623415919503695 0.7078971145915912 0.09547591591089447 0.2113855759166693 0.9672460666638539 0.04463372855705448 0.03841115532807166 1.5047996464441908e-07 6.822521319496058 -0.3549524786065319 SYSCSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 SYSCSSPK 8 0 Q8N1W1-5;Q8N1W1-4;Q8N1W1-3;Q8N1W1;Q8N1W1-6;Q8N1W1-2 Q8N1W1-5 ARHGEF28 Rho guanine nucleotide exchange factor 28 1 SYSCS(0.151)S(0.849)PK;SYS(0.002)CS(0.116)S(0.882)PK 89.029 0.010532 6158500.0 114931.0 121427.0 105527.0 103520.0 87048.0 73063.0 67535.0 71136.0 65947.0 49931.0 True False 113292.06286423566 121145.84324195265 96850.97740599989 111133.20613259662 81928.00778295276 69938.26580817172 71031.6318487072 74441.23825473578 58519.35440730355 58561.50682112455 1.93458244184674 2.06869409306682 1.653833425117118 1.897717667546563 1.3990078505527686 1.1942702571127028 1.2129406448791098 1.271163299846701 0.9992802027114883 1.0 15.837665055019015 -6.349705209194414 0.9258405124970852 1.098906634269903 1.990726081754853 0.8918273459181134 0.12392440197828142 0.1746151409465662 0.32236598381840886 0.06155593026751484 0.08920183621500967 4.469868953747073e-07 6.349705209194414 0.8918194474849501 SYSEDDIHR ddPTM_PC-9_AZD4547_30min_R2 2 SYSEDDIHR 9 0 Q9Y5A9;A0A024R7W5;A0A087X0Q1;A0A087WY31;Q9Y5A9-2;Q7Z739;Q9BYJ9 Q9Y5A9 YTHDF2;YTHDF3;YTHDF1 YTH domain-containing family protein 2;YTH domain-containing family protein 3;YTH domain-containing family protein 1 0 ; 170.5 8.5072e-05 15748200.0 74623.0 53752.0 115110.0 147536.0 113736.0 101613.0 87011.0 124855.0 97417.0 99931.0 False True 98351.56174517628 71126.28282234973 113583.56618846221 113523.85460847763 97945.71962626575 95259.12304671443 94754.810437358 105561.5286324754 102566.26373925286 96432.44610662929 1.0199011402907374 0.7375762587594481 1.1778563209199135 1.1772371146009268 1.015692576313611 0.9878326942094007 0.982602995806865 1.094668162993104 1.0636074047716384 1.0 16.55723102352875 -5.266389627244492 24.999422600468538 1.0627330460663782 0.8787387010668071 0.3872869835045426 0.09242185455317069 381.71080872503376 1927701.377925584 0.02445602473810025 0.05357121766569189 5.415148524221933e-06 5.266389627244492 -0.18399434499957112 SYSEDDIHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SYSEDDIHR 9 0 Q9Y5A9;A0A024R7W5;A0A087X0Q1;A0A087WY31;Q9Y5A9-2;Q7Z739;Q9BYJ9 Q9Y5A9 YTHDF2;YTHDF3;YTHDF1 YTH domain-containing family protein 2;YTH domain-containing family protein 3;YTH domain-containing family protein 1 0 ; 190.02 0.0075206000000000005 10875100.0 90595.0 94650.0 139971.0 128174.0 153833.0 131115.0 130855.0 134798.0 117670.0 93263.0 False True 105930.94416718782 104046.22647994186 143308.43948297363 120992.82632571492 123690.52794943053 124239.09858523395 118459.46709184106 131259.69533028675 119390.70114023087 110170.84363049845 0.9615152310394317 0.9444080035267959 1.3007837170024332 1.0982290989030843 1.1227156285039959 1.1276949008570631 1.0752342742254184 1.1914195353765114 1.0836869103104525 1.0 16.749382944124292 -5.204770875325382 24.999848354402218 1.1290924623749308 0.9529612149888298 0.4568007712681942 0.07492082484697879 229.81960241931958 101386.11974032315 0.01782913330018825 0.04717140158271529 6.2406399174108515e-06 5.204770875325382 -0.17613124738610098 SYSEDDIHR ddPTM_PC-9_Lapatinib_30min_R1 2 SYSEDDIHR 9 0 Q9Y5A9;A0A024R7W5;A0A087X0Q1;A0A087WY31;Q9Y5A9-2;Q7Z739;Q9BYJ9 Q9Y5A9 YTHDF2;YTHDF3;YTHDF1 YTH domain-containing family protein 2;YTH domain-containing family protein 3;YTH domain-containing family protein 1 0 ; 209.21 0.00034125 14017500.0 118968.0 101191.0 123961.0 108711.0 115159.0 114862.0 91851.0 89584.0 129217.0 93617.0 False True 117271.49450394096 100956.69845665651 113769.40508329777 116705.96958926508 108385.57403130503 109949.62001639979 96606.59534960527 93746.39968247051 114663.22074466672 109798.57371318877 1.0680602719874361 0.9194718568965328 1.0361646899028163 1.0629097049486227 0.9871309832714702 1.0013756672614489 0.879852916869002 0.8538034376234332 1.0443051932913552 1.0 16.744499788249193 -7.116562392994 7.045554499937145 0.9324883123319612 1.0114703314121272 0.2034924421659855 0.06445791480561897 0.3690125883498664 20.15779484765866 0.024406119311542327 0.01889486740321125 7.646058333147853e-08 7.116562392994 0.078982019080166 SYSEHDDER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SYSEHDDER 9 0 E9PQA4;Q9UBU9-2;Q9UBU9 E9PQA4 NXF1 Nuclear RNA export factor 1 0 ; 144.65 0.00045068 3424800.0 15596.599999999999 20962.3 41300.0 32867.0 41122.0 32781.0 30799.0 22960.0 27340.0 22593.4 False True 18236.796333108465 23043.298608985577 42284.7486311222 31025.568546251714 33064.43929674699 31061.906652347596 27881.49575454976 22357.324328130864 27739.795777801603 26689.404570744013 0.6832972344800453 0.8633875119958588 1.5843271632021816 1.1624676175901223 1.238860133020392 1.1638291356412112 1.044665334539253 0.8376853919265841 1.0393561124330586 1.0 14.703979499476052 -7.524608020598333 7.318293995633635 0.9508965325931845 1.1313588016007852 0.0853561230887121 0.22680386735590816 0.3128885127224877 114.22362783319427 0.11038671995646519 0.0667951971387581 2.988078339898926e-08 7.524608020598333 0.18046226900760065 SYSEHDDER ddPTM_PC-9_Lapatinib_30min_R1 1 SYSEHDDER 9 0 E9PQA4;Q9UBU9-2;Q9UBU9 E9PQA4 NXF1 Nuclear RNA export factor 1 0 102.06 0.002768 2119000.0 9608.9 12398.0 20527.0 13413.0 21298.0 19904.0 15094.0 19540.0 23022.0 16311.0 False True 9471.875323943557 12369.293192730853 18839.349296511435 14399.436764456319 20045.29351347907 19052.752318490195 15875.493464490795 20447.899734277074 20429.019927592493 19130.334616958662 0.4951233480018132 0.6465800750691376 0.9847893240618345 0.7527017719643808 1.0478276472858616 0.9959445404368572 0.8298596852779295 1.0688730826564015 1.0678861785032538 1.0 14.22357448825725 -4.536386577563669 0.7491909746677503 0.9948722749967307 3.888631700240192e-18 0.7361869791774407 0.09725008620100586 1.9620727984216837 0.6519568295943545 0.03840174024253983 1.785460540340594 2.9081273608083145e-05 4.536386577563669 -0.9948722749967307 down SYSFDEIRK ddPTM_PC-9_AZD4547_30min_R2 1 SYSFDEIRK 9 1 P43490 P43490 NAMPT Nicotinamide phosphoribosyltransferase 0 76.17 0.01576 10993000.0 46672.0 38496.0 58151.0 84828.0 60532.0 63507.0 54787.0 54172.0 52231.0 55869.0 False True 61512.72516209293 50939.07916968994 57379.879744811595 65272.215179535444 52128.1766583766 59535.89725062438 59662.93686351761 45800.9621487202 54991.82402830015 53913.043315200084 1.1409618411348375 0.9448377616503115 1.064304224292122 1.2106943174757265 0.966893602232982 1.1042948716983114 1.1066512516220062 0.849533977908593 1.0200096423196336 1.0 15.71834672951586 -7.739548407204805 24.999927336130927 0.9510787786540403 1.073343798349776 0.29929969705436443 0.08419502069156835 273.0795753509813 311862.9079508739 0.038676568798664476 0.022305854818512234 1.821594023794471e-08 7.739548407204805 0.12226501969573567 SYSPS(ph)FQR ddPTM_PC-9_AZD4547_30min_R2 2 SYSPSFQR 8 0 Q9P227;Q9P227-2 Q9P227 ARHGAP23 Rho GTPase-activating protein 23 1 S(0.001)YS(0.231)PS(0.768)FQR;S(0.001)YS(0.351)PS(0.648)FQR 112.11 0.0037351999999999997 25391000.0 61029.0 58929.0 115570.0 141605.0 110537.0 127105.0 92733.0 127235.0 100850.0 114646.0 True False 80434.95251794162 77976.64683059692 114037.46628790353 108960.15502544102 95190.84555750633 119157.10425686324 100986.0573523752 107573.75431943448 106180.72511064439 110632.27843552656 0.7270477807687644 0.7048272704248747 1.030779334029186 0.9848857545579701 0.8604256090864197 1.0770555026244417 0.9128082579554491 0.9723541432993762 0.959762617313568 1.0 16.755412846852053 -5.25480746669855 24.9903649036835 0.9714908199294158 0.7159374906636176 0.7709657670502726 0.056405258615034655 221.36846406910092 834154.8733383286 0.013851339740104579 0.03488705416024036 5.56150757777383e-06 5.25480746669855 -0.2555533292657982 SYSPYDMLESIR ddPTM_PC-9_Lapatinib_30min_R1 2 SYSPYDMLESIR 12 0 P07355;P07355-2;H0YN42;A6NMY6;H0YM50;H0YN28;H0YL33 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ; 128.51 0.00093321 35757000.0 35230.0 34762.0 45001.0 37622.0 35241.0 38576.0 35571.0 35366.0 41768.0 39161.0 False True 34727.613739609274 34681.510724770895 41301.19148888344 40388.84738331292 33168.193666471765 36926.19440504812 37412.692329760306 37009.23346993055 37063.64800346118 45929.92667124752 0.7560999169055722 0.7550961483786078 0.8992218033463202 0.8793579766064952 0.7221477600841741 0.8039680679081987 0.8145602451654017 0.8057760190829699 0.806960748462577 1.0 15.487146859796484 SYSPYDMLESIRK ddPTM_PC-9_AZD4547_30min_R2 1 SYSPYDMLESIRK 13 1 P07355;P07355-2;H0YN42;A6NMY6;H0YM50;H0YN28;H0YL33 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 70.622 0.017580000000000002 2068300.0 10358.0 11537.0 14951.0 25028.0 17548.0 18236.0 17286.0 24157.0 15411.0 21842.0 False True 13651.628540215954 15266.109631668567 14752.739971190138 19258.18127874537 15111.763100528522 17095.700037198818 18824.420512580808 20424.09072263593 16225.593997819944 21077.318228187374 0.6476928607529963 0.7242908925317031 0.6999343944743798 0.9136922007938746 0.7169680192197827 0.8110946493342872 0.893112696254038 0.9690080351551621 0.769813019956255 1.0 14.363403696950614 -2.598802811409744 0.14824719412899173 1.021505799479229 1.189546684062399e-17 0.5750963070554198 0.07571261900261758 37.04449980756027 0.4847431633198092 0.2956414790028131 7.68253814395662 0.002518820322179998 2.598802811409744 -1.021505799479229 SYSPYDMLESIRK ddPTM_PC-9_Lapatinib_30min_R1 2 SYSPYDMLESIRK 13 1 P07355;P07355-2;H0YN42;A6NMY6;H0YM50;H0YN28;H0YL33 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ; 74.53699999999999 0.012256999999999999 6008700.0 35691.0 24213.0 35442.0 26818.0 27742.0 30295.0 19691.9 22580.9 28188.0 22607.4 False True 35182.03979507222 24156.9362861423 32528.095570076395 28790.28518222543 26110.270102870527 28999.35347109427 20711.450228793317 23630.091049628292 25013.170607200816 26515.058967533023 1.3268701321068785 0.9110647770280963 1.2267781719779003 1.0858088310298823 0.9847336238188967 1.0936937197312364 0.781120277882615 0.8911951158985807 0.9433571555631376 1.0 14.694524336478905 -6.682446792845206 1.2439868729339376 0.90367251617394 1.1311133184991464 0.38569037085729674 0.12130304629732915 0.46368935301971154 1.5121384032201541 0.055639523890526635 0.05401058612109143 2.0775582399547197e-07 6.682446792845206 0.22744080232520647 SYSS(ph)ERR ddPTM_PC-9_AZD4547_30min_R2 1 SYSSERR 7 1 A0A0A0MT33;Q9UPN6;Q9UPN6-2 A0A0A0MT33 SCAF8 Protein SCAF8 1 SYS(0.147)S(0.852)ERR 58.433 0.038118 17383000.0 11910.0 13555.0 16012.0 20034.0 12234.0 18363.0 10236.0 12854.0 17252.0 16406.0 True False 15697.132256610545 17936.388667527724 15799.670417945063 15415.470822214525 10535.520274211643 17214.75870712229 11146.9841702405 10867.709655535136 18163.905499343957 15831.630933597768 0.9915044332734039 1.1329463617967026 0.9979812240579157 0.9737133771543354 0.6654728321043186 1.08736483179312 0.704095757221352 0.6864554701355351 1.147317391084241 1.0 13.950522265385407 -5.904286493424635 3.306075961665136 0.8647086708186258 1.0519691254965673 0.15517003522418016 0.16129900621858376 0.3830368965425796 8.307982478308203 0.04596179601367483 0.07185187922881134 1.2465609172668182e-06 5.904286493424635 0.1872604546779415 SYSS(ph)PDITQAIQEEEK ddPTM_PC-9_Lapatinib_30min_R1 1 SYSSPDITQAIQEEEK 16 0 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 S(0.001)YS(0.332)S(0.667)PDITQAIQEEEK 146.86 2.9966e-05 2474300.0 9315.8 8272.8 9305.8 9446.0 8595.9 10131.0 8821.5 7142.7 9654.7 5429.2 True False 9182.954983691514 8253.644839879318 8540.713045426808 10140.69035093227 8090.306062189625 9697.720746514473 9278.234106068998 7474.575917708331 8567.28601750183 6367.629986045736 1.4421307462612287 1.2961878843410604 1.3412703100122414 1.5925376275246772 1.2705364601773386 1.522971775647521 1.457093789432123 1.1738395500505523 1.3454434438364828 1.0 12.636540790015028 -8.777084580920759 0.8065747365881757 1.0027122063390652 1.4109487830292504 0.5312328499822715 0.11275267844766779 0.7766469910056125 1.003009184608346 0.10950891545974097 0.0384444558268433 1.670765193136686e-09 8.777084580920759 0.4082365766901852 SYSS(ph)PDITQAIQEEEKR ddPTM_PC-9_Lapatinib_30min_R1 1 SYSSPDITQAIQEEEKR 17 1 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 S(0.074)Y(0.052)S(0.233)S(0.641)PDITQAIQEEEKR 59.606 0.017556 2931900.0 12007.0 8135.8 11076.0 10547.0 9948.2 9953.9 8230.8 11677.0 11551.0 9358.1 True False 11835.777978185866 8116.962054962065 10165.374034596407 11322.6615637606 9363.066434913724 9528.194900674207 8656.950550386295 12219.556048984312 10250.004742577574 10975.635116115564 1.0783683908011257 0.7395437228998166 0.9261763831480287 1.03161789217423 0.8530774151890218 0.8681224184178576 0.7887425610273125 1.1133347564590859 0.9338871631699432 1.0 13.422016804718657 -7.7645224441581355 24.99965003970068 1.0177081904170253 0.8952109342273622 0.21260343135970283 0.10376571026848642 122.25858666152959 991322.2384889488 0.05227590106903381 0.02679089267062915 1.7197984604726892e-08 7.7645224441581355 -0.12249725618966312 SYSSGGEDGYVR ddPTM_PC-9_AZD4547_30min_R2 1 SYSSGGEDGYVR 12 0 Q13347 Q13347 EIF3I Eukaryotic translation initiation factor 3 subunit I 0 95.48299999999999 0.021112 5236500.0 11896.0 11111.0 16361.0 24950.0 19380.0 14900.0 11266.0 17684.0 14400.0 15325.0 False True 15678.680547828635 14702.413462552602 16144.042449912515 19198.162973657396 16689.421523150384 13968.30064456363 12268.6521748661 14951.344137893522 15161.154601817352 14788.47641456697 1.06019579761339 0.9941804044174831 1.091663670911378 1.2981839667233597 1.128542322771732 0.9445395355808628 0.8296089354263169 1.0110131509670681 1.025200580289886 1.0 13.852185805727272 -6.761825572281996 24.999960522791312 0.9544817733925112 1.1167959344783993 0.4260866555114471 0.0882441538580414 10.922797348390466 707043.8598088915 0.033426152536543824 0.031319643071237226 1.7305112529634401e-07 6.761825572281996 0.16231416108588814 SYSSGGEDGYVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SYSSGGEDGYVR 12 0 Q13347 Q13347 EIF3I Eukaryotic translation initiation factor 3 subunit I 0 ; 99.53 0.015281999999999999 4098700.0 20435.5 18697.8 23699.0 25489.0 26926.0 23335.9 25637.8 24132.0 20450.1 21127.6 False True 23894.826530477014 20553.994014544685 24264.074038958002 24060.93396645295 21650.043589908302 22112.124323495897 23209.20198240187 23498.560569967525 20749.144024711804 24957.866634010425 0.9574066117460219 0.8235477140716618 0.972201446332477 0.9640621259536979 0.8674637102357736 0.8859781425934621 0.9299353315228625 0.9415292145982428 0.831366892410454 1.0 14.607206999323616 -10.74941091188542 4.675070300082456 1.0000220362796044 0.9089762133439586 0.22284350507830375 0.05142937703896475 1.1471678633377454e-05 1.8979281332630554e-06 0.048359813290481314 0.0117261393867322 1.780693150255869e-11 10.74941091188542 -0.09104582293564578 SYSSGGEDGYVR ddPTM_PC-9_Lapatinib_30min_R1 2 SYSSGGEDGYVR 12 0 Q13347 Q13347 EIF3I Eukaryotic translation initiation factor 3 subunit I 0 ; 125.74 0.0013095000000000001 13982900.0 29568.0 26490.0 32514.0 28636.0 27872.0 22179.0 28428.0 27202.0 27679.0 23950.0 False True 29146.354897892896 26428.66403254076 29840.824427669537 30741.986966895656 26232.62375846035 21230.45587177421 29899.862740727698 28465.904225783255 24561.49954720843 28089.725588630987 1.0376162204193824 0.9408658674557319 1.0623394783090117 1.0944210497854825 0.933886793435879 0.7558085893287263 1.0644412543791224 1.0133920367418798 0.8743944283011946 1.0 14.777754910248898 -6.291443679907343 23.466549858508003 0.9379705294410096 1.0292095171985605 0.21536020830019087 0.08717676818357718 560.0166600637831 437990.47679032525 0.02823274194615123 0.032019155410665384 5.111593628086129e-07 6.291443679907343 0.0912389877575509 SYSSSHS(ph)SPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 SYSSSHSSPAK 11 0 Q9H792;H0YN99 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 SYSSSHS(0.843)S(0.156)PAK 67.118 0.041252 0.0 7243.2 6844.4 15647.0 12603.0 19518.0 17448.0 12650.0 11690.0 15072.0 8912.7 True False 8469.330700278984 7523.86679893622 16020.083821577957 11896.894769477294 15693.588011135336 16532.99616455145 11451.700421931053 11383.149886578836 15292.399486577393 10528.501957105622 0.8044193499496939 0.7146189296054989 1.5215919498182835 1.129970324168307 1.490581288304157 1.5703085046580088 1.0876856430845196 1.0811746944584475 1.4524762923424872 1.0 13.36201255733744 -5.249502118077096 24.972662769841705 1.2986102337553007 0.7595190506918865 0.5325371808103653 0.19936786486393657 556.1707969331342 1163499.816723473 0.05065951228829745 0.13180569634850564 5.62986371673317e-06 5.249502118077096 -0.5390911830634142 SYT(ph)MDDAWK ddPTM_PC-9_AZD4547_30min_R2 1 SYTMDDAWK 9 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 S(0.021)YT(0.979)MDDAWK 104.82 0.010227 6605600.0 85134.0 74318.0 86365.0 86349.0 116330.0 104900.0 90569.0 104200.0 101250.0 95850.0 True False 112204.84110279447 98339.8401322999 85219.7436701114 66442.57212875121 100179.5875019653 98340.58641709585 98629.46554459866 88098.284277794 106601.86829402827 92494.32067446926 1.2130997912584898 1.0631986852295912 0.9213510953828129 0.7183421819226466 1.0830890672146682 1.063206753668718 1.0663299630225065 0.9524723640909049 1.1525233929682026 1.0 16.49707716370464 SYT(ph)MDDAWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SYTMDDAWK 9 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 SYT(1)MDDAWK;S(0.003)YT(0.997)MDDAWK 90.05 0.033894 8613100.0 140322.0 129091.0 131665.0 156168.0 139439.0 125481.0 114472.0 133210.0 99788.0 97345.0 True False 164075.74311416855 141906.30134730256 134804.3929422934 147418.41326348748 112116.92892123671 118900.55546332421 103628.38345448945 129713.37864766202 101247.21071965134 114992.8779174042 1.426833957769272 1.2340442635867366 1.1722847134856405 1.2819786401847733 0.9749901989735992 1.0339819092859541 0.9011721884978171 1.1280122821243859 0.8804650562130818 1.0 16.811184985072323 -5.322528100494046 0.5420924836696794 0.9650962004651437 1.5228295693837715 0.7165719413351347 0.08932470589022817 1.349261640509188 0.4567780823332293 0.055481777651211206 0.4432924905867388 4.758520005701623e-06 5.322528100494046 0.5577333689186278 SYVS(ph)EPELATLSGDMAQPSLGLVGPESR ddPTM_PC-9_AZD4547_30min_R2 2 SYVSEPELATLSGDMAQPSLGLVGPESR 28 0 H0YDE2;A0A1B0GTN9;E9PKC0;Q6IQ23-3;Q6IQ23;Q6IQ23-2;A0A1B0GUM1;A0A1B0GUN0 H0YDE2 PLEKHA7 Pleckstrin homology domain-containing family A member 7 1 S(0.201)YVS(0.799)EPELATLSGDMAQPSLGLVGPESR;S(0.066)YVS(0.934)EPELATLSGDMAQPSLGLVGPESR 115.76 2.5678e-12 9201300.0 22296.1 24640.6 33914.0 55069.0 44583.0 39289.0 25963.0 36639.0 33202.0 36620.0 True False 29385.796012310166 32605.192076804396 33464.27820098606 42373.69285756868 38393.42000859717 36832.252619077895 28273.6567030045 30977.28443046149 34956.989936773585 35337.94494626049 0.8315649383969005 0.9226680308203582 0.9469786160988203 1.1990989550186824 1.0864644242041588 1.0422862075055537 0.8000934051485203 0.876601185427438 0.9892196614696686 1.0 15.108930522946464 -7.2303168015571195 24.980656127895394 0.9061952780857718 1.0110178939818704 0.1369617450402285 0.10676154133546942 1284.6295794829512 1031114.4549799915 0.04460320148107994 0.03454564209495144 5.884142725937666e-08 7.2303168015571195 0.10482261589609854 SYVS(ph)EPELATLSGDMAQPSLGLVGPESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 SYVSEPELATLSGDMAQPSLGLVGPESR 28 0 H0YDE2;A0A1B0GTN9;E9PKC0;Q6IQ23-3;Q6IQ23;Q6IQ23-2;A0A1B0GUM1;A0A1B0GUN0 H0YDE2 PLEKHA7 Pleckstrin homology domain-containing family A member 7 1 S(0.011)YVS(0.989)EPELATLSGDMAQPSLGLVGPESR;S(0.027)YVS(0.972)EPELATLSGDMAQPSLGLVGPESR 111.43 6.364199999999999e-11 8854800.0 27689.0 27389.0 37238.0 42713.0 46468.0 37765.0 34075.0 31675.0 31729.7 34201.0 True False 32376.200817321744 30107.998912404917 38125.89514590141 40319.929087414406 37362.92897332909 35784.53691851706 30847.169318363663 30843.564812436667 32193.686835805096 40401.37056503296 0.8013639231670786 0.7452222162597408 0.9436782617196421 0.9979841902272236 0.9247936010781375 0.8857258161803122 0.7635178927583617 0.7634286753413141 0.7968464036135561 1.0 15.302116614948229 -7.229732849364871 21.01514820812695 0.8112340142306381 0.8867265727380167 0.05465996157591324 0.09207817301778803 212.75182824510173 141011.38533778308 0.03711704816592901 0.02874230824920748 5.892059863466379e-08 7.229732849364871 0.07549255850737857 SYVS(ph)EPELATLSGDMAQPSLGLVGPESR ddPTM_PC-9_Lapatinib_30min_R1 2 SYVSEPELATLSGDMAQPSLGLVGPESR 28 0 H0YDE2;A0A1B0GTN9;E9PKC0;Q6IQ23-3;Q6IQ23;Q6IQ23-2;A0A1B0GUM1;A0A1B0GUN0 H0YDE2 PLEKHA7 Pleckstrin homology domain-containing family A member 7 1 S(0.011)YVS(0.989)EPELATLSGDMAQPSLGLVGPESR;S(0.069)Y(0.001)VS(0.926)EPELAT(0.004)LSGDMAQPSLGLVGPESR 121.91 8.517299999999999e-13 5376000.0 21301.1 17714.6 20508.8 19274.1 18687.4 18590.3 17788.0 14376.5 18892.0 15929.1 True False 20997.342407856664 17673.58293208177 18822.645630257386 20691.581610512767 17588.243872842002 17795.236205105906 18708.975602647555 15044.484673993562 16764.184018420536 18682.423710808416 1.1239089067286805 0.9460005407037739 1.0075055528993193 1.1075426791943481 0.9414326612593957 0.9525121836740464 1.0014212230838002 0.8052747816274939 0.8973238311002382 1.0 14.189394010653686 -6.841276689753323 1.1582009637445407 0.9042049421750852 1.0346457084087508 0.3329331128511258 0.07274339551904692 0.5425241772579146 1.5307499660058934 0.03921915479153779 0.032758406443978545 1.4411968699949593e-07 6.841276689753323 0.13044076623366563 SYVTTSTR ddPTM_PC-9_Lapatinib_30min_R1 2 SYVTTSTR 8 0 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 0 ; 127.12 0.015992 26022000.0 63770.0 64919.0 80893.0 78612.0 102841.0 96194.0 84333.0 70680.0 77894.0 71421.0 False True 62860.62810601423 64768.684044111506 74242.28979601007 84393.3887219444 96792.0945731853 92080.00685916618 88699.35009546192 73964.05083002578 69120.7574598163 83766.02468749968 0.7504310768061894 0.7732094758673306 0.8863055167411946 1.0074894808102113 1.1555054084789282 1.0992524379983761 1.0588941092330293 0.8829838959883619 0.8251645905088668 1.0 16.354077588224598 -5.496432907523821 2.475331947228886 1.0118090434576106 0.7586300055646337 0.5337007577995327 0.09085316384883765 0.2518609571870794 3.0348783316174845 0.029563209244026008 0.07064922381967258 3.1883580947718944e-06 5.496432907523821 -0.2531790378929769 T(ph)ADGRVSPAGGTLDDKPK ddPTM_PC-9_Lapatinib_30min_R1 1 TADGRVSPAGGTLDDKPK 18 2 C9JA69;Q8WY36-2;Q8WY36 C9JA69 BBX HMG box transcription factor BBX 1 T(0.982)ADGRVS(0.018)PAGGTLDDKPK 81.884 0.024243999999999998 9174300.0 17367.0 18671.0 16316.0 22100.0 21618.0 19555.0 20669.0 22087.0 21273.0 21422.0 True False 17119.34339528226 18627.76844664282 14974.561461581356 23725.307723438826 20346.47174262328 18718.67823493145 21739.139685806287 23113.242652557707 18877.010725378994 25124.764156979258 0.6813732972107036 0.7414106787334092 0.5960080408325609 0.9442997186044556 0.8098174221854876 0.7450290127293274 0.8652475123738625 0.9199386910916423 0.7513308625480276 1.0 14.616822433506552 -2.1362023997174266 0.08858056081771097 1.116910286584347 1.0871159504633153e-13 0.44101061678859965 0.08964796667594672 136.42024502966663 0.9898399803496473 1.8800724100549928 18.572748134110636 0.007307984209321264 2.1362023997174266 -1.1169102865842382 T(ph)ADSVSPLEPPTKDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TADSVSPLEPPTKDK 15 1 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 T(0.644)ADS(0.15)VS(0.206)PLEPPTKDK 65.905 0.023756 5652900.0 15733.0 12330.0 16249.0 26444.0 29329.0 31768.0 29074.0 28857.0 28989.0 23873.0 True False 18396.286159085674 13554.040913868801 16636.437784675665 24962.428412604735 23582.19298998813 30102.0301556322 26319.90024246823 28099.53432651884 29412.909283200075 28200.98592143598 0.6523277664949434 0.4806229452980287 0.5899239775170437 0.8851615501013541 0.8362187426951964 1.0674105593149215 0.9332971661271634 0.9964025514852647 1.0429745032723448 1.0 14.783457980439563 -5.917199060080652 1.5498961661406276 0.9926978794872066 0.5444276159752118 0.8647405842340201 0.07168654005899093 0.12572750196110793 0.6138536593622259 0.02339105471371808 0.043889396831897486 1.2100433796835837e-06 5.917199060080652 -0.4482702635119947 T(ph)ALATSPITVGDLGIVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TALATSPITVGDLGIVR 17 0 P13994 P13994 CCDC130 Coiled-coil domain-containing protein 130 1 T(0.673)ALAT(0.101)S(0.226)PITVGDLGIVR 96.334 0.007991700000000001 0.0 11096.0 9356.3 9638.9 12068.0 15332.0 14003.0 11736.0 13531.0 8441.7 8506.3 True False 12974.333644010332 10285.131630367458 9868.72793173181 11391.869084983893 12327.804661682907 13268.658029127351 10624.281118718001 13175.825587279578 8565.14389237263 10048.42485416625 1.2911808400130445 1.0235566051034422 0.9821169063766314 1.1336969973219861 1.2268395137145887 1.3204714392252173 1.0573081127549053 1.3112329323751328 0.8523867189812714 1.0 13.294681748298565 -8.273540253407804 24.958629098837235 0.9261933411332177 1.1594399893495095 0.3948610883796614 0.11948507699657664 903.5743532940949 1863645.7675356835 0.11415630967703407 0.030395318863000304 5.326718503340423e-09 8.273540253407804 0.23324664821629182 T(ph)APSPLVEAK ddPTM_PC-9_Lapatinib_30min_R1 2 TAPSPLVEAK 10 0 Q8TEH3;Q8TEH3-7;Q8TEH3-6;A0A0A0MS48;Q8TEH3-4;Q8TEH3-3;Q8TEH3-5;Q8TEH3-2 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 T(0.771)APS(0.229)PLVEAK;T(0.838)APS(0.162)PLVEAK 115.91 0.002651 12217600.0 128819.0 166323.0 156818.0 159939.0 143410.0 139648.0 118015.0 115998.0 129812.0 97800.0 True False 126982.01743748876 165937.88931235461 143925.0293749857 171701.4476008635 134974.90575490816 133675.58057538766 124125.2392481701 121387.69055151824 115191.20557903915 114704.59968969146 1.107035095201162 1.4466541861552524 1.2547450561210605 1.4969011536186405 1.1767174648623826 1.165389887912238 1.0821295709497627 1.0582634949244096 1.0042422526268702 1.0 16.80756371946495 -6.890936723624502 1.447079384739581 1.0317759222296936 1.3269644495916124 0.5887103174870862 0.1054474296654772 0.2746104566100754 1.187512675435526 0.0491342813163412 0.03980267104347905 1.2854739388746838e-07 6.890936723624502 0.2951885273619188 T(ph)ASAPNLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASAPNLDR 9 0 Q86W92-2 Q86W92-2 PPFIBP1 Liprin-beta-1 1 T(0.957)AS(0.043)APNLDR 88.155 0.025274 9417000.0 19207.0 26048.0 21821.0 27666.0 24073.0 25981.0 28370.0 29709.0 24718.0 19125.0 True False 22458.365744458053 28633.873294765184 22341.295396603346 26115.96371438219 19356.068459476428 24618.51062306345 25682.588218986853 28929.170229287465 25079.453988138248 22592.21110658329 0.994075597050072 1.2674223501046065 0.9888937072694567 1.1559720113792709 0.8567584805294307 1.0896901815816382 1.1367894934154115 1.2804930908625234 1.1100929373322908 1.0 14.463537854193536 -7.2306974727628415 4.412110969007702 1.156140400555866 1.0592795900841943 0.0702893896820801 0.12066102997520894 0.46444698735675893 21.924298657387496 0.04817410463062424 0.035293003521033296 5.878987370738764e-08 7.2306974727628415 -0.09686081047167172 T(ph)ASAPNLDR ddPTM_PC-9_Lapatinib_30min_R1 1 TASAPNLDR 9 0 Q86W92-2 Q86W92-2 PPFIBP1 Liprin-beta-1 1 T(0.608)AS(0.392)APNLDR 91.469 0.019015 11588000.0 20462.0 21417.0 23801.0 20483.0 20629.0 15228.0 17685.0 14759.0 20976.0 14118.0 True False 20170.208127728758 21367.41025235655 21844.173654516904 21989.388149284932 19415.642778174464 14576.733938201794 18600.64276663043 15444.757020378467 18613.46199292765 16558.27748894749 1.21813444310208 1.2904367780174668 1.319229833483447 1.3279997369269034 1.1725641626149967 0.8803291252928719 1.123344066376844 0.9327514308591405 1.1241182547732986 1.0 14.015264980683448 -6.541988651800089 5.8089045715155585 1.0147259166898888 1.2872427813710647 0.7522497204059223 0.07511866417917072 0.0778577699788698 8.722882348536457 0.023297541934646466 0.023923483255222176 2.870855597063893e-07 6.541988651800089 0.272516864681176 T(ph)ASEGDGGAAAGAAAAGAR ddPTM_PC-9_AZD4547_30min_R2 3 TASEGDGGAAAGAAAAGAR 19 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 T(0.985)AS(0.015)EGDGGAAAGAAAAGAR;T(0.999)AS(0.001)EGDGGAAAGAAAAGAR;T(0.956)AS(0.044)EGDGGAAAGAAAAGAR 297.73 5.292499999999998e-121 146622000.0 152163.0 155251.0 185943.0 220161.0 207137.0 209320.0 177839.0 222864.0 175866.0 227720.0 True False 200547.66881298355 205432.84965122453 183477.27432700194 169406.28290354242 178379.60299488137 196231.18731007096 193666.32648020715 188425.48970524187 185161.91772244533 219747.5921125735 0.9126273780066991 0.9348582511247007 0.8349455507708553 0.7709130337899586 0.8117477023525249 0.8929844710632577 0.8813126215325932 0.8574632736303851 0.8426118163223812 1.0 17.745487831540274 -10.77850859286132 4.230447083616505 1.0001001167899275 0.8589005058810716 0.4551052016809186 0.04596366446089541 4.861113546451052e-05 8.553447848382029e-06 0.04984555661131273 0.0120807631051182 1.665295878257228e-11 10.77850859286132 -0.1411996109088559 T(ph)ASEGDGGAAAGAAAAGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TASEGDGGAAAGAAAAGAR 19 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 T(1)ASEGDGGAAAGAAAAGAR;T(0.994)AS(0.006)EGDGGAAAGAAAAGAR 298.93 3.871199999999999e-121 95066000.0 72159.0 87169.0 89878.0 99596.0 123777.0 126752.0 134284.0 110967.0 118402.0 108594.0 True False 84374.0934947855 95822.5622401483 92021.0323842133 94015.95901458843 99523.7853906293 120104.90198585652 121563.64738803096 108054.23382925511 120133.40525542309 128281.23257036896 0.6577274929791612 0.7469725720602554 0.7173382305454148 0.7328894268537354 0.7758249854360832 0.9362624569418032 0.9476339208180508 0.8423230090962972 0.9364846505471768 1.0 16.968950595307618 -6.634712505464652 3.164179206315691 0.9244818447226549 0.7184007227307424 0.85471961844618 0.04297876072582298 0.09558626186957261 1.9071872704014785 0.015050346013243746 0.015003562243310545 2.3189292282165894e-07 6.634712505464652 -0.20608112199191253 T(ph)ASEGDGGAAAGAAAAGAR ddPTM_PC-9_Lapatinib_30min_R1 4 TASEGDGGAAAGAAAAGAR 19 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 T(0.867)AS(0.133)EGDGGAAAGAAAAGAR;T(0.949)AS(0.051)EGDGGAAAGAAAAGAR;T(0.957)AS(0.043)EGDGGAAAGAAAAGAR;T(0.996)AS(0.004)EGDGGAAAGAAAAGAR 284.24 1.5657999999999996e-105 203166000.0 109505.4 119472.4 151064.5 134739.3 157676.2 190018.0 170997.0 176524.0 191397.0 165458.1 True False 107943.83291516897 119195.76899816227 138644.55993583341 144648.47759912835 148401.99591933656 181891.3730935927 179850.38796525312 184725.94947254483 169839.85436023885 194057.31212594 0.5562471814775791 0.6142297226131123 0.7144516144068582 0.7453905035294619 0.7647328219357492 0.9373074948886657 0.9267900600856163 0.9519143981168859 0.8752046109451191 1.0 17.566123269678606 -5.702423081839578 0.4918607501342013 0.9701835531522738 0.45672433111335514 0.9254582651069598 0.039412795260770676 0.5156696908052839 0.18106590677037238 0.030778650366298996 0.1401121937864356 1.9841610416901684e-06 5.702423081839578 -0.5134592220389187 T(ph)ASEINFDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TASEINFDK 9 0 Q9Y4K4 Q9Y4K4 MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 1 T(0.989)AS(0.011)EINFDK;T(0.677)AS(0.323)EINFDK 156.01 0.00020646 21701500.0 74820.0 123942.0 86030.0 106246.0 123236.0 76145.0 133220.0 88793.0 74325.0 76438.0 True False 87485.54823764006 136246.1426558581 88081.28147059181 100293.38107417968 99088.79045702805 72151.82215438846 120600.43717072351 86462.2778339603 75411.86251591446 90295.60431712492 0.9688793701450213 1.5088900914528625 0.9754769585598404 1.1107227404109488 1.0973822170680736 0.7990623984417432 1.335618030166405 0.9575469203384287 0.8351664855252793 1.0 16.4623681370868 T(ph)ASELLLDRR ddPTM_PC-9_AZD4547_30min_R2 2 TASELLLDRR 10 1 Q92508 Q92508 PIEZO1 Piezo-type mechanosensitive ion channel component 1 1 T(0.856)AS(0.144)ELLLDRR;T(0.955)AS(0.045)ELLLDRR 134.49 9.474e-05 21918000.0 42691.0 70485.0 77285.0 70004.0 62218.0 39365.0 67545.0 70903.0 53361.0 48751.0 True False 56265.84997203699 93267.89784070016 76260.1504028781 53865.65935101854 53580.104660854995 36903.50032706358 73556.37414799661 59946.570538852386 56181.553521359376 47044.24232864951 1.1960198992889637 1.982557125463595 1.6210304731900502 1.145000040062604 1.1389301221294237 0.7844424418456345 1.563557419718533 1.2742594539001741 1.1942280445049347 1.0 15.52173054411437 -5.756716460827276 16.285015456090058 1.1692655621662602 1.638154510652932 0.3810025463709097 0.2568561918807147 1.5502249598505002 5331.7668508069555 0.07010099550578454 0.1150880162480238 1.7509894894198193e-06 5.756716460827276 0.46888894848667184 T(ph)ASELLLDRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TASELLLDRR 10 1 Q92508 Q92508 PIEZO1 Piezo-type mechanosensitive ion channel component 1 1 T(0.997)AS(0.003)ELLLDRR;T(0.996)AS(0.004)ELLLDRR;T(0.94)AS(0.06)ELLLDRR;T(0.958)AS(0.042)ELLLDRR;T(0.987)AS(0.013)ELLLDRR 129.34 0.00021181 18686100.0 86354.7 74164.1 76688.9 64495.7 155834.0 71468.9 64322.3 66627.0 66469.4 58059.0 True False 100972.84512693055 81526.62171453821 78517.454220273 60882.215026880636 125299.44636372918 67720.945070192 58229.22609087556 64878.11184714183 67441.38922724956 68584.6371052089 1.47223706924392 1.1887009271402327 1.1448256859597747 0.8876946441152305 1.8269316810923664 0.9874069168917233 0.849012673225228 0.945956916672443 0.9833308459997303 1.0 16.06559782979159 -6.969479083281111 24.999789516619256 0.9369477473480952 1.2798365348306775 0.36591700459463106 0.23034336897403945 232.0688497180936 190087.78212796204 0.08083133923117404 0.07128579487293456 1.0728053156042445e-07 6.969479083281111 0.34288878748258234 T(ph)ASELLLDRR ddPTM_PC-9_Lapatinib_30min_R1 3 TASELLLDRR 10 1 Q92508 Q92508 PIEZO1 Piezo-type mechanosensitive ion channel component 1 1 T(0.976)AS(0.024)ELLLDRR;T(0.906)AS(0.094)ELLLDRR;T(0.991)AS(0.009)ELLLDRR 136.53 9.807e-05 24480200.0 212629.0 189734.0 74569.9 41060.7 66385.2 52569.6 35093.7 35361.9 97542.2 18268.8 True False 209596.8714686168 189294.68258022223 68439.05067013827 44080.440852479805 62480.553054324846 50321.32075372293 36910.68007120711 37004.94296896275 86555.9702710978 21426.53773835415 9.7821157122101 8.834590305337993 3.194125504823409 2.057282487294925 2.916035890506135 2.3485511923676894 1.7226618934862201 1.7270612462377803 4.039661998968691 1.0 14.38711112684581 -5.263772984633561 3.2498089979771243 2.3044594445791002 9.670508088834909 0.930156852656679 0.7655899699361863 0.053002253327909025 1.1602775032655406 0.1979421986291229 0.5598838296951887 5.447873508687888e-06 5.263772984633561 7.366048644255809 T(ph)ASEPNLK ddPTM_PC-9_AZD4547_30min_R2 1 TASEPNLK 8 0 P56524-2;P56524;Q9UQL6-2;Q9UQL6;Q9UQL6-3;Q9UKV0-10;Q9UKV0-3;Q9UKV0-4;Q9UKV0-2;Q9UKV0;Q9UKV0-5;Q9UKV0-7 P56524-2;Q9UKV0-10 HDAC4;HDAC5;HDAC9 Histone deacetylase 4;Histone deacetylase 5;Histone deacetylase 9 1 T(0.7)AS(0.3)EPNLK 103.26 0.009849799999999999 63869000.0 157550.0 169470.0 288090.0 364780.0 300680.0 311070.0 237950.0 283800.0 263790.0 262580.0 True False 207647.62275642267 224247.86333352447 284269.73836533783 280685.60679481935 258935.7721145948 291618.74372512836 259127.08902977005 239945.23107522007 277733.40086204157 253387.15412313127 0.8194875682431719 0.8850009153366677 1.1218790445359335 1.1077341618447738 1.0218977872444441 1.150882114503006 1.0226528251856426 0.9469510477181522 1.0960831926273558 1.0 17.95098386098097 -5.125154659094276 4.605839660999873 1.0586246383241622 0.8340879781484919 0.6618147338800374 0.059617307698235686 0.1280241460147062 4.131217070524935 0.015763761854906248 0.04640556710210385 7.496272077569953e-06 5.125154659094276 -0.2245366601756703 T(ph)ASESNVYLNSFHYPDHSYK ddPTM_PC-9_AZD4547_30min_R2 1 TASESNVYLNSFHYPDHSYK 20 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;E9PGF6;A0A1W2PRJ2;A0A1W2PRT1 E9PFQ4;A0A1W2PRT1 PHLDB2 Pleckstrin homology-like domain family B member 2 1 T(0.423)AS(0.423)ES(0.151)NVY(0.002)LNSFHYPDHSYK 70.316 0.042954 9600800.0 9166.8 11872.0 32082.0 30375.0 34632.0 45884.0 30297.0 48353.0 36048.0 38324.0 True False 12081.65171871515 15709.391830386507 31656.57171799357 23372.51303907187 29823.944591834043 43014.866226520644 32993.374306934 40881.15489140269 37953.42368654943 36982.28842491772 0.3266875099750409 0.42478149675026383 0.8559927756299738 0.6319920706508813 0.8064385916080691 1.1631207277464832 0.8921398786318454 1.105425235498894 1.0262594691402975 1.0 15.174546879497926 -5.126105677056505 0.5437913482062368 1.0554118648880921 2.411710937027582e-18 0.8047832280056018 0.11819518448364708 1.2579303065840068 0.3702218127100618 0.07225443537973912 0.8028631534643865 7.479874702637657e-06 5.126105677056505 -1.0554118648880921 down T(ph)ASESNVYLNSFHYPDHSYK ddPTM_PC-9_Lapatinib_30min_R1 1 TASESNVYLNSFHYPDHSYK 20 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;E9PGF6;A0A1W2PRJ2;A0A1W2PRT1 E9PFQ4;A0A1W2PRT1 PHLDB2 Pleckstrin homology-like domain family B member 2 1 T(0.499)AS(0.499)ES(0.002)NVYLNSFHYPDHSYK 152.17 0.00011326 6179600.0 23180.0 26814.0 43438.0 24040.0 47208.0 47690.0 33526.0 39060.0 55318.0 36591.0 True False 22849.448949308608 26751.913830447258 39866.69531552895 25807.9817950891 44431.318254499005 45650.40987081981 35261.81223602212 40874.870195540556 49087.504315635524 42915.70559555727 0.5324262675451393 0.6233595244258706 0.9289535092638915 0.6013644990089781 1.035316037285395 1.0637226916652545 0.8216528598721792 0.9524454888555302 1.1438121227282623 1.0 15.389218098095816 -4.4200978247224585 0.4271989662901878 1.025609809566957 1.7597092273851348e-16 0.6111588797797076 0.12722883606351368 5.083558558160352 0.5752246945243848 0.09575122225370596 2.8241418671128096 3.801037683991732e-05 4.4200978247224585 -1.0256098095669568 T(ph)ASGSSVTSLDGTR ddPTM_PC-9_AZD4547_30min_R2 1 TASGSSVTSLDGTR 14 0 Q92597;E5RJY1;E7ESM1;Q92597-3;Q92597-2 Q92597 NDRG1 Protein NDRG1 1 T(0.969)AS(0.031)GS(0.001)SVTSLDGTR 201.3 7.1093e-08 123070000.0 73654.0 52201.0 66554.0 115190.0 74730.0 58113.0 75999.0 64413.0 51189.0 60044.0 True False 97074.43990162828 69073.95240380787 65671.45047438884 88634.72516775939 64355.029433696 54479.184923323955 82762.76377042865 54459.4509134888 53894.74603558528 57941.87783597118 1.675376144633045 1.192124849652797 1.1334021769245979 1.5297178565506144 1.1106824948939338 0.9402385106942887 1.428375587079235 0.939897927845196 0.930151870261385 1.0 15.82231882116057 -1.522878745280359 0.23723641204444867 0.9713625880095654 4.161053966723932 0.4265125648590863 0.19245184204181912 54.5547573548703 0.7249630654230133 0.2733405880989847 68.25106458796432 0.029999999999998524 1.522878745280359 3.1896913787143664 T(ph)ASGSSVTSLDGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASGSSVTSLDGTR 14 0 Q92597;E5RJY1;E7ESM1;Q92597-3;Q92597-2 Q92597 NDRG1 Protein NDRG1 1 T(0.963)ASGSS(0.036)VT(0.001)SLDGTR 187.62 1.0297e-05 5247200.0 23288.0 26650.0 25243.0 29343.0 30334.0 21660.0 18444.0 24092.0 16213.0 10612.0 True False 27230.19844103393 29295.635876285764 25844.888854610588 27699.006841289534 24390.27045444099 20524.11146974923 16696.850797003655 23459.610527584024 16450.08445301746 12535.871595454224 2.1721823036946377 2.336944475955624 2.061674663609549 2.209579655501081 1.9456381846863704 1.6372305119327892 1.3319257994839617 1.871398438389476 1.312240982029731 1.0 13.613774687067494 -7.106102023943226 0.30002860506414836 0.9624341258465511 2.528494451439659 0.8265034474210825 0.17727679433754645 0.8416468216068024 0.19084501576643825 0.2745829351641271 0.4730029327986244 7.832456220220007e-08 7.106102023943226 1.5660603255931078 up T(ph)ASGSSVTSLDGTR ddPTM_PC-9_Lapatinib_30min_R1 2 TASGSSVTSLDGTR 14 0 Q92597;E5RJY1;E7ESM1;Q92597-3;Q92597-2 Q92597 NDRG1 Protein NDRG1 1 T(0.978)AS(0.019)GS(0.003)SVTSLDGTR;T(0.877)AS(0.061)GS(0.061)SVTSLDGTR 259.27 1.12e-44 116040000.0 86043.0 99905.0 141940.0 121679.0 178762.0 266698.0 254830.0 285090.0 244325.0 238762.0 True False 84816.01104164639 99673.67611064478 130270.24110424449 130627.6795692449 168247.57061961418 255291.9482434032 268023.850507234 298336.3221722133 216806.54564369042 280031.6935696325 0.30288004175697386 0.35593712568773933 0.46519820468768325 0.4664746261542825 0.6008161736084986 0.9116537667188106 0.9571196998834969 1.065366274685723 0.7742214564358926 1.0 18.09523059292185 -6.553643973320065 1.512748186057162 0.9645612582653535 0.37596184457204207 0.9111463325694585 0.08078495095907919 0.10497319513491551 0.4930152501794631 0.03292529161487465 0.03544424048624234 2.794834056257186e-07 6.553643973320065 -0.5885994136933115 down T(ph)ASISSSPSEGTPTVGSYGCTPQSLPK ddPTM_PC-9_AZD4547_30min_R2 2 TASISSSPSEGTPTVGSYGCTPQSLPK 27 0 Q6PKG0;Q6PKG0-3 Q6PKG0 LARP1 La-related protein 1 1 T(0.97)AS(0.023)IS(0.007)SSPSEGTPTVGSYGCTPQSLPK;T(0.938)AS(0.059)IS(0.003)SSPSEGTPTVGSYGCTPQSLPK 227.36 4.795399999999999e-54 25612000.0 100945.0 102587.0 122994.0 149908.0 117662.0 110570.0 85053.0 95192.0 78637.0 100683.0 True False 133043.41021356432 135746.24155187525 121363.01919714813 115349.02665551241 101326.66229395886 103656.04042076507 92622.55223050655 80482.26369454661 82793.59127938276 97158.11881552015 1.3693493846477378 1.3971682779246133 1.2491289526466363 1.1872299305684624 1.0429047364158395 1.0668798622746383 0.9533176780251834 0.828363750510269 0.8521530911543052 1.0 16.568046936198876 -6.122257798482432 0.6753300382463766 0.8827133309839056 1.4342884878288147 0.9107626671237404 0.056797830477348765 0.24338957811059495 0.22604855275080285 0.0357823372282668 0.07993450837457906 7.546441357046354e-07 6.122257798482432 0.5515751568449091 T(ph)ASISSSPSEGTPTVGSYGCTPQSLPK ddPTM_PC-9_Lapatinib_30min_R1 2 TASISSSPSEGTPTVGSYGCTPQSLPK 27 0 Q6PKG0;Q6PKG0-3 Q6PKG0 LARP1 La-related protein 1 1 T(0.928)AS(0.027)IS(0.044)S(0.001)SPSEGTPTVGSYGCTPQSLPK;T(0.668)AS(0.104)IS(0.212)S(0.008)S(0.008)PS(0.001)EGTPTVGSYGCTPQSLPK 234.49 9.732699999999998e-65 22968000.0 202648.0 195316.0 203248.0 183673.0 190672.0 211656.0 201482.0 210386.0 189747.0 132788.0 True False 199758.20235890846 194863.7578021797 186537.7339999688 197180.92513516644 179457.04783557542 202603.96627423406 211913.75210100244 220161.30161185385 168375.69473550902 155740.22887111196 1.2826371439599273 1.2512101671781009 1.1977491965441012 1.2660885794533545 1.1522844748359211 1.3009096477051267 1.3606873037048042 1.4136443949498476 1.0811316764845258 1.0 17.24878212595963 -8.458600921686239 6.014802024439076 1.0005984914159443 1.2729678637261437 0.6544564134956379 0.07016949520903214 0.12605305498433433 8.384768856556024 0.07367709440625939 0.01909936937083514 3.478556632891346e-09 8.458600921686239 0.2723693723101994 T(ph)ASLNQRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASLNQRPR 9 1 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 T(0.606)AS(0.394)LNQRPR 86.189 0.0085455 72832000.0 22797.0 19085.0 20357.0 17677.0 25303.0 13284.0 11427.0 18976.0 12386.0 11976.0 True False 26656.081838725982 20979.632671629046 20842.388084352413 16686.614999607238 20345.058789105315 12587.363654854507 10344.55183568427 18477.900106733952 12567.121817990139 14147.153998036158 1.8842010090811379 1.4829578213781613 1.4732566060456864 1.179503312250902 1.4381025888266659 0.8897452912862776 0.7312108030435134 1.306121366127701 0.8883144850006333 1.0 13.788224232897214 -4.436025561393711 0.4454740854731147 0.9560294108142225 2.7580954073952912 0.698066948580768 0.18527759182604242 4.0162943843703625 0.4927083082336961 0.13379549343335895 4.0758055962656154 3.664160077620822e-05 4.436025561393711 1.8020659965810686 T(ph)ASLNQRPR ddPTM_PC-9_Lapatinib_30min_R1 1 TASLNQRPR 9 1 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 T(0.543)AS(0.457)LNQRPR 78.488 0.015518 43981000.0 37257.0 27316.0 36186.0 37962.0 20455.0 23682.0 23094.0 25093.0 33744.0 29830.0 True False 36725.70834790296 27252.751480290044 33210.92676199945 40753.852117519666 19251.8771160773 22669.176065438336 24289.69432019017 26258.912386500237 29943.39537992709 34986.07575402348 1.049723570202909 0.7789599402886995 0.9492612716983589 1.1648591972431455 0.5502725498976058 0.6479485217152807 0.6942674706064113 0.7505532364109285 0.8558660762770324 1.0 15.094493231960568 -6.263964023924864 24.999998266653343 0.729474644777836 0.9683309355454844 0.3808709186449528 0.1452844487404554 241.03677457577865 2386834.486125054 0.0445080421847875 0.05284105401168819 5.445477602074655e-07 6.263964023924864 0.23885629076764847 T(ph)ASLPGYGR ddPTM_PC-9_AZD4547_30min_R2 1 TASLPGYGR 9 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;O14639-4 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 T(0.5)AS(0.5)LPGYGR 117.71 0.0045037 61600000.0 22847.0 28312.0 43770.0 62796.0 45814.0 63259.0 41398.0 47227.0 47095.0 40011.0 True False 30111.87075287834 37463.30032866436 43189.581201190034 48319.35238852867 39453.5169072039 59303.4047298289 45082.341801447445 39929.15231849682 49584.345553651954 38610.227068400556 0.7798936457828436 0.9702947424343208 1.1186046931212512 1.2514651183720769 1.0218411002170331 1.5359506854173381 1.1676269533867571 1.0341599972401017 1.2842282814294261 1.0 15.236695418405551 -4.956485517803717 1.478173487987612 1.1953961554691659 0.693814095954392 0.4250309652522696 0.149534005737307 0.7739497753033066 2.0122203403798804 0.04289180499696006 0.5216620733479373 1.1053873295549908e-05 4.956485517803717 -0.5015820595147739 T(ph)ASLPGYGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TASLPGYGR 9 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;O14639-4 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 T(0.863)AS(0.137)LPGYGR;T(0.998)AS(0.002)LPGYGR 120.27 0.0035731 47645000.0 62855.0 59443.0 80941.0 114511.0 121774.0 92708.0 97905.0 76807.0 100493.0 72232.0 True False 73495.11005716199 65344.108194898916 82870.9404104519 108095.3199196708 97913.25886197329 87846.22927689341 88630.72962918239 74790.89763374337 101962.5200109225 85327.08981180278 0.8613338415650015 0.7658072991710103 0.9712148931040757 1.2668347198771874 1.1475049609441799 1.0295233257180907 1.038717361914793 0.8765199633399192 1.1949607121936394 1.0 16.38071622346724 -5.482512328855418 5.801886461908398 1.076551357086454 0.8229075385795632 0.5035433741347821 0.10478520944208963 0.1662838739630479 14.829095151231604 0.02903835334080325 0.05945731642403108 3.2922110719337086e-06 5.482512328855418 -0.2536438185068908 T(ph)ASLPGYGR ddPTM_PC-9_Lapatinib_30min_R1 1 TASLPGYGR 9 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;O14639-4 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 T(0.985)AS(0.015)LPGYGR 125.68 0.0034689 77306000.0 43458.0 37077.0 45568.0 32960.0 42946.0 41896.0 29446.0 29686.0 33388.0 24743.0 True False 42838.28095077884 36991.150484504076 41821.574937566766 35383.98835133679 40420.00071508461 40104.2057443461 30970.56979961547 31065.319934071093 29627.491848773283 29019.794582024897 1.476174506669776 1.2746868479702025 1.4411395924722155 1.219305265973658 1.3928424131617076 1.3819603591952019 1.067222226955352 1.0704872443622744 1.0209407845748433 1.0 14.824749686805834 -7.2854731086729405 6.284972676326924 1.0435878025413563 1.3587385621093335 0.8284264933712082 0.07236895021634598 0.07179858064355947 10.831651956514545 0.02857613736031832 0.019714327310597822 5.182351799126688e-08 7.2854731086729405 0.3151507595679772 T(ph)ASLTSAASVDGNR ddPTM_PC-9_AZD4547_30min_R2 2 TASLTSAASVDGNR 14 0 Q9UN36-6;Q9UN36-2;Q9UN36-5;Q9UN36-4;A0A0A0MS87;H0YJT9;G3V578;Q9UN36-3;Q9UN36 Q9UN36-6;Q9UN36-3 NDRG2 Protein NDRG2 1 T(0.896)AS(0.076)LT(0.022)S(0.006)AASVDGNR;T(0.993)AS(0.006)LT(0.001)SAASVDGNR 263.72 7.0728999999999995e-56 77323000.0 44958.0 47364.0 62966.0 81624.0 64316.0 58297.0 45883.0 61145.0 45333.0 50262.0 True False 59253.70881550772 62673.48674649824 62131.02969874646 62806.84787822889 55386.833574971104 54651.67937423666 49966.49811285116 51696.44522231957 47729.209830846215 48502.342678562156 1.2216669452071152 1.2921744246840199 1.2809902835107412 1.2949240059282594 1.1419414097589944 1.126784323314603 1.0301873137137385 1.0658546034554572 0.9840598864916753 1.0 15.565766811160982 -6.7476909108037875 1.1842611230645996 1.0170662874992076 1.2784436822733705 0.9142985317126876 0.034040640634738786 0.12146812850402362 0.36027959969372825 0.016997585750106972 0.015530046767476614 1.7877594780744684e-07 6.7476909108037875 0.2613773947741629 T(ph)ASLTSAASVDGNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TASLTSAASVDGNR 14 0 Q9UN36-6;Q9UN36-2;Q9UN36-5;Q9UN36-4;A0A0A0MS87;H0YJT9;G3V578;Q9UN36-3;Q9UN36 Q9UN36-6;Q9UN36-3 NDRG2 Protein NDRG2 1 T(0.799)AS(0.2)LTSAASVDGNR;T(0.998)AS(0.001)LT(0.001)SAASVDGNR;T(0.914)AS(0.079)LT(0.007)SAASVDGNR;T(0.858)AS(0.135)LT(0.007)SAASVDGNR 214.48 6.480500000000001e-15 60078100.0 59475.0 61869.0 46893.2 54863.7 92157.0 70582.0 90792.0 75024.0 79558.0 62656.0 True False 69542.94281520495 68010.94544202334 48011.31173145132 51789.86475951527 74099.49740455984 66880.55566749029 82191.52448284294 73054.6994944986 80721.38524105109 74015.0368153769 0.9395785749411011 0.9188801136675759 0.6486697000666329 0.6997208538678419 1.001141127435951 0.9036076795356752 1.1104706289326245 0.9870251051381119 1.0906079185288053 1.0 16.175530776442493 -6.329245666686516 7.941092303873781 1.0146576899634294 0.7993786892966879 0.535825536230113 0.09746799530563784 0.27198496349739176 29.15126971563567 0.032626851952993564 0.037042158958336145 4.6854826419744486e-07 6.329245666686516 -0.21527900066674155 T(ph)ASPPALPK ddPTM_PC-9_AZD4547_30min_R2 1 TASPPALPK 9 0 Q13029-5;Q13029-3;Q13029-2;Q13029 Q13029-5 PRDM2 PR domain zinc finger protein 2 1 T(0.888)AS(0.112)PPALPK 82.831 0.037172000000000004 2704200.0 31925.0 32141.0 48079.0 63459.0 61213.0 59097.0 51597.0 54601.0 48112.0 56048.0 True False 42076.485918748236 42529.94969848828 47441.441045739455 48829.507981776514 52714.63156329227 55401.65524777024 56189.033043366406 46163.67005615951 50655.10209740532 54085.77657968347 0.7779584315805803 0.7863425911215266 0.8771518880910391 0.9028160649563198 0.9746486950340609 1.0243294771990212 1.0388874228436795 0.8535269894506834 0.9365697471825367 1.0 15.722961625063828 -5.5796721705072425 1.4055513696050612 0.9688397898755262 0.7703830326766529 0.6867596458630725 0.04980600589047631 0.29967373171895234 1.1232459751500656 0.017685096133061753 0.05489263428591101 2.6322542131980804e-06 5.5796721705072425 -0.19845675719887335 T(ph)ASPPALPK ddPTM_PC-9_Lapatinib_30min_R1 1 TASPPALPK 9 0 Q13029-5;Q13029-3;Q13029-2;Q13029 Q13029-5 PRDM2 PR domain zinc finger protein 2 1 T(0.72)AS(0.28)PPALPK 92.23899999999999 0.017561 3884300.0 52715.0 47631.0 56731.0 41699.0 42125.0 49711.0 43730.0 44681.0 52118.0 32957.0 True False 51963.274433252955 47520.71334593989 52066.79616799285 44765.683563786195 39647.29032093651 47584.97641200089 45994.12542746666 46757.04237600989 46247.922013129435 38653.5735375579 1.3443329989337889 1.2294002597137932 1.3470111920545182 1.1581253547046417 1.025708277202703 1.231062798521455 1.189906164375107 1.209643458465185 1.1964720925011616 1.0 15.238314177569967 -1.5228787452848418 0.022525779920904175 3.5234394627251247e-14 2.7752536163322077 0.4545614236160652 0.07959268898540275 2605.228831955482 4.534650966515256 199.5482559517911 387.8679947650718 0.02999999999968886 1.5228787452848418 2.7752536163321726 T(ph)ASPPGPPPYGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASPPGPPPYGK 12 0 P54259 P54259 ATN1 Atrophin-1 1 T(0.995)AS(0.005)PPGPPPYGK 107.34 0.0038213 26921000.0 166040.0 140230.0 162590.0 168310.0 199360.0 156880.0 154750.0 137360.0 170270.0 112440.0 True False 194147.29256051494 154151.1076522157 166466.76222600855 158880.13636838266 160296.83911773463 148652.9366285438 140090.95970702235 133754.4455449504 172759.87663080782 132824.4819254498 1.4616830402506948 1.1605624612090402 1.2532837306261138 1.1961660536162082 1.2068320297134998 1.1191682020787252 1.05470736777013 1.0070014473688862 1.300662905862283 1.0 17.019161560106504 -1.5228787452803376 0.3721621673942527 1.0884641870766865 5.228262765050592 0.5072678558506639 0.09475068397208576 57.34817264918484 0.7903635983673241 0.07308881741619781 170.04452658651556 0.029999999999999995 1.5228787452803376 4.139798577973905 T(ph)ASPPPPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASPPPPPK 9 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 T(0.812)AS(0.188)PPPPPK 118.71 0.0043553 160330000.0 148650.0 142280.0 141620.0 180730.0 196590.0 154900.0 158830.0 161650.0 140260.0 124980.0 True False 173813.509028671 156404.61810423815 144996.75789684113 170604.28403456602 158069.60073312288 146776.77131413465 143784.47257038046 157406.85878233227 142311.0371541498 147637.8846588641 1.1772961217257276 1.059379971920017 0.9821107788957718 1.1555589842591465 1.0706574474320232 0.9941673958095569 0.9738995712557964 1.066168478003059 0.9639195080786842 1.0 17.17170344648796 -6.698309437821518 5.242114685436041 1.0021395338487755 1.086323000142545 0.3915854307815628 0.055827851517980843 0.24012635265382012 12.838442979547663 0.018990887626491888 0.01870898931104 2.003044335865101e-07 6.698309437821518 0.0841834662937695 T(ph)ASPPPPPK ddPTM_PC-9_Lapatinib_30min_R1 1 TASPPPPPK 9 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 T(0.583)AS(0.417)PPPPPK 84.213 0.019793 0.0 36539.0 31511.0 35433.0 28088.0 42449.0 33523.0 28624.0 33620.0 36300.0 30280.0 True False 36017.94715956806 31438.03821553007 32519.835515335395 30153.68521882124 39952.23327794501 32089.2994359298 30106.010661692344 35182.10793584416 32211.51174405385 35513.85765443617 1.0141941635864196 0.8852329848656423 0.915694257485802 0.8490681443910847 1.1249758803083567 0.9035712129099386 0.8477257231426586 0.9906585839865646 0.9070124698219086 1.0 15.116094459611087 -11.354171266968134 2.525815635610328 1.0239005996603323 0.9362155011453913 0.050943743823428256 0.08064682869996949 47201629.30330439 28845056.612833302 6830569.658817643 0.019591975389129133 4.424138690532011e-12 11.354171266968134 -0.087685098514941 T(ph)ASPPPPPKR ddPTM_PC-9_AZD4547_30min_R2 1 TASPPPPPKR 10 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 T(0.654)AS(0.346)PPPPPKR 71.61399999999999 0.027769 37043000.0 28688.0 27180.0 32772.0 37022.0 32390.0 26773.0 27017.0 30302.0 21727.0 26109.0 True False 37810.18725253092 35965.40346613087 32337.421867155583 28487.149884198167 27893.207592097053 25098.88007764446 29421.460661135938 25619.522170688168 22875.444863450393 25194.9318569611 1.5007060732368824 1.4274856415693777 1.283489157690303 1.1306698524103156 1.1070959727319305 0.9961876547290561 1.1677531349626211 1.0168522112358784 0.907938350193638 1.0 14.620845933902075 -5.1340030121808615 0.60449620202765 1.003065634565367 1.737808562012921 0.8954021638705266 0.059869218829974515 0.7809625897351606 0.28962634595848297 0.033441519800123984 0.37689070791140755 7.345087737314758e-06 5.1340030121808615 0.7347429274475541 T(ph)ASPPPPPKR ddPTM_PC-9_Lapatinib_30min_R1 2 TASPPPPPKR 10 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 T(0.852)AS(0.148)PPPPPKR;T(0.968)AS(0.032)PPPPPKR 91.265 0.0069458 433184000.0 235961.0 209228.0 231785.0 220040.0 218456.0 221843.0 194213.0 179627.0 224235.0 171989.0 True False 232596.15287005206 208743.54542092961 212728.53201597382 236222.47563192176 205606.8475810207 212355.29203129123 204268.39884849254 187973.12618060334 198979.29300076913 201717.0694890629 1.1530811619423382 1.0348333234746288 1.054588650106817 1.171058434619633 1.0192833363175975 1.052738335774827 1.0126480588176896 0.9318652440109697 0.9864276409764012 1.0 17.621973645771185 -7.065721722477975 1.2983416236580991 0.9703508600593155 1.0914918178669042 0.5421402756517439 0.0467226931225118 0.34696303494605496 1.1796133139643168 0.026377006831417468 0.018084233380567874 8.595641173917413e-08 7.065721722477975 0.12114095780758871 T(ph)ASQEGCQELTQEQR ddPTM_PC-9_AZD4547_30min_R2 1 TASQEGCQELTQEQR 15 0 A0A0C4DG33;O43933-2;O43933 A0A0C4DG33 PEX1 Peroxisome biogenesis factor 1 1 T(0.875)AS(0.125)QEGCQELTQEQR 149.19 0.00032364 6150800.0 8246.4 7245.1 10068.0 9994.4 8935.5 7191.8 6410.8 10395.0 6081.7 6080.1 True False 10868.583664224445 9586.93688934748 9934.491741685666 7690.345491940742 7694.960062957182 6742.095609098845 6981.348780634794 8788.691603336529 6403.166245963369 5867.237549638407 1.8524192300504805 1.6339779680368176 1.6932145081287737 1.3107267989199947 1.311513296991259 1.1491090231235574 1.1898868456527807 1.4979266697456572 1.0913425938170838 1.0 12.518465688934436 -1.5228787452807946 0.2751149154798993 1.10436363517315 6.879915155663881 0.765044390008065 0.13059394419274847 26.060922963777543 0.365790563008337 0.15377705145878945 71.9207173551313 0.02999999999996843 1.5228787452807946 5.7755515204907315 T(ph)ASQEGCQELTQEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASQEGCQELTQEQR 15 0 A0A0C4DG33;O43933-2;O43933 A0A0C4DG33 PEX1 Peroxisome biogenesis factor 1 1 T(0.875)AS(0.125)QEGCQELTQEQR 88.95100000000001 0.01146 6207100.0 6330.8 8942.3 6865.8 6518.7 10618.0 9078.4 10351.0 10761.0 8945.3 5824.3 True False 7402.479401000411 9830.032446398136 7029.506710691497 6153.4783729105475 8537.47912195077 8602.312722390187 9370.478345249669 10478.535152221968 9076.108089655037 6880.199484866571 1.0759105774887237 1.428742359581275 1.0217010024423472 0.8943749939875302 1.2408766839870689 1.2502998991979102 1.3619486420212992 1.5229987408461283 1.3191635082120083 1.0 12.748234679771947 -6.730991937508385 2.584004125961449 1.3366505289782669 1.1206531269530642 0.1696011986395939 0.1777612895865918 0.4350510807684343 5.949677705677921 0.06769754820166403 0.06387716154388652 1.8578389447582756e-07 6.730991937508385 -0.21599740202520268 T(ph)ASQEGCQELTQEQR ddPTM_PC-9_Lapatinib_30min_R1 1 TASQEGCQELTQEQR 15 0 A0A0C4DG33;O43933-2;O43933 A0A0C4DG33 PEX1 Peroxisome biogenesis factor 1 1 T(0.5)AS(0.5)QEGCQELTQEQR 234.36 1.4390999999999996e-93 0.0 8031.4 7036.1 7089.9 3175.8 8916.9 10017.0 10497.0 6641.3 8585.4 8838.3 True False 7916.870763221624 7019.808342746693 6506.995789805443 3409.3589261582333 8392.42547329991 9588.596260767497 11040.483297784538 6949.8790432576425 7618.42184373002 10365.988378705526 0.7637352535996437 0.6771962389198921 0.6277255532306527 0.3288985865700907 0.809611699984168 0.9250054997616053 1.0650680759458115 0.670450205938348 0.7349440849635012 1.0 13.339570060982297 -6.500842799942783 24.375760634388058 0.8698077596512939 0.6022561514441008 0.4411059705060242 0.14937188888738595 578.5650751189502 639998.8047830489 0.04899114182088503 0.055046434012701394 3.156146836090933e-07 6.500842799942783 -0.26755160820719304 T(ph)ASTDLK ddPTM_PC-9_AZD4547_30min_R2 2 TASTDLK 7 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 T(0.999)AS(0.001)TDLK;T(0.948)AS(0.052)TDLK 132.76 0.010469 127631000.0 730800.0 665680.0 720280.0 1010620.0 1032950.0 1003590.0 979780.0 873290.0 1146570.0 1141590.0 True False 963179.1984156988 880848.0419181021 710728.6165774092 777637.1729233513 889542.7225148707 940835.3586495032 1066978.5219146374 738343.0967078186 1207175.3494309518 1101623.281572954 0.8743271992585545 0.7995909823731958 0.6451648476079722 0.7059011786797036 0.8074835902566766 0.854044548973339 0.9685511733113982 0.6702319286985062 1.0958150300775098 1.0 20.071199523974066 -6.757773262574857 2.3679545682088845 0.9067235197681457 0.7523896364628117 0.3057418794958261 0.11675583674649649 0.4096549747444993 4.713529002892118 0.044165837026909814 0.04090272751905654 1.7467338535880153e-07 6.757773262574857 -0.15433388330533404 T(ph)ASTDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASTDLK 7 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 T(0.971)AS(0.029)TDLK 117.81 0.017597 53610000.0 185570.0 219540.0 161440.0 238420.0 254850.0 219520.0 192350.0 177030.0 182440.0 202200.0 True False 216983.33582543224 241334.48031068585 165289.34186460942 225062.1003680688 204913.97195603268 208007.98475712602 174129.2155065961 172383.15007878974 185107.83985742932 238857.2593856808 0.9084226135035363 1.0103711351766165 0.6920004955667607 0.9422451758297323 0.8578930047303265 0.8708464012862899 0.7290095178787559 0.7216994389123594 0.7749726356800287 1.0 17.865789198516538 -7.150134558953786 6.870590560271397 0.7835044862756649 0.8802429742075318 0.09038208063090647 0.10548424021890342 0.4736028182509747 25.810498612064112 0.039235522175034114 0.030342641949372418 7.077264730823804e-08 7.150134558953786 0.0967384879318669 T(ph)ASTDLK ddPTM_PC-9_Lapatinib_30min_R1 2 TASTDLK 7 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 T(0.998)AS(0.002)TDLK;T(0.997)AS(0.003)TDLK 129.42 0.010818000000000001 125908000.0 583390.0 586530.0 483350.0 489190.0 522230.0 415820.0 382160.0 396800.0 477410.0 384060.0 True False 575070.7516193772 585171.9258212949 443610.828784956 525166.6644900003 491513.45814368356 398036.3479237634 401946.3748767593 415236.7765896188 423639.0584498272 450444.25927221874 1.2766746157416171 1.2990995306872268 0.9848295758096607 1.165886019589883 1.091174874640028 0.8836528376826677 0.8923332168250577 0.9218383141579282 0.9404916362666035 1.0 18.78098906361219 -5.353675497234882 0.5822803760830355 0.9186772354173394 1.416904806939157 0.7045066355426352 0.07990225671680001 1.1975188041581344 0.4862833150803717 0.04851673997722486 0.3695291884488074 4.4291919586260985e-06 5.353675497234882 0.4982275715218176 T(ph)ATCHSSSSPPIDAASAEPYGFR ddPTM_PC-9_AZD4547_30min_R2 1 TATCHSSSSPPIDAASAEPYGFR 23 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.321)AT(0.321)CHS(0.096)S(0.096)S(0.096)S(0.069)PPIDAASAEPYGFR 64.76100000000001 0.0039494 7614000.0 2294.9 2155.7 7965.3 7273.1 7607.8 1380.7 935.56 6518.5 2949.3 3153.8 True False 3024.630463114653 2852.4878679889002 7859.67491756544 5596.399163274852 6551.588290186969 1294.364610734833 1018.8230275801283 5511.215605228397 3105.193976884714 3043.38642194201 0.9938371418456323 0.9372742966266847 2.582542545665337 1.8388723570974412 2.15272968393095 0.42530406306698576 0.3347662394215483 1.8108826291311522 1.020308809455509 1.0 11.571461810636006 -6.758338541423981 24.99983504382817 0.9324646444102643 1.7152475991177623 0.305200751434644 0.5901611910434289 114.81257402539724 925652.7024209631 0.21460736782569953 0.20596897873958367 1.7444617791627546e-07 6.758338541423981 0.7827829547074979 T(ph)AVPSPVEAAAASDPAAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TAVPSPVEAAAASDPAAAR 19 0 Q147X3;Q147X3-2;J3KNC2 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 T(0.894)AVPS(0.105)PVEAAAAS(0.001)DPAAAR 101.38 0.00097278 6098100.0 48195.0 55997.0 61032.0 71106.0 68596.0 72208.0 70555.0 54167.0 58735.0 52907.0 True False 56353.4616053603 61556.01208871949 62487.23434514896 67122.16134876237 55155.10622050624 68421.28536508096 63871.51962603518 52745.173644680515 59593.88825929685 62498.620288418424 0.9016752905152231 0.98491793586244 0.9998178208860145 1.0739782900647605 0.8825011810817045 1.094764733194599 1.0219668743290828 0.8439414086466591 0.9535232615421456 1.0 15.931536720923734 -7.727244090290114 24.999988819110992 0.9240489248103804 0.9967248704963083 0.13077576392936596 0.07176493224023954 302.35179853772 221047.7730815656 0.03296211219695822 0.019029372158833793 1.8739409847484477e-08 7.727244090290114 0.07267594568592795 T(ph)CARCQES(ph)LGRLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 TCARCQESLGRLSPK 15 2 Q96C24-2;Q96C24 Q96C24-2 SYTL4 Synaptotagmin-like protein 4 3 T(1)CARCQES(1)LGRLS(1)PK 84.94 0.018502 0.0 7804.0 5782.0 7081.8 4484.9 5562.2 5451.6 3838.5 6206.2 8312.2 4977.8 True False 7692.713528921677 5768.612134245023 6499.561740538538 4814.734507187818 5235.042331705946 5218.447776300298 4037.2387480752554 6494.562708846996 7375.992504653561 5838.206097498424 1.317650216599561 0.9880795638092974 1.1132806262737958 0.8246941657730879 0.8966867980130191 0.8938443914366636 0.6915204226526271 1.1124243646742464 1.2634005003376043 1.0 12.511309425716494 T(ph)CSFGGFDLTNR ddPTM_PC-9_AZD4547_30min_R2 2 TCSFGGFDLTNR 12 0 O94885;A0A1B0GWB9 O94885 SASH1 SAM and SH3 domain-containing protein 1 1 T(0.999)CS(0.001)FGGFDLTNR;T(0.763)CS(0.237)FGGFDLTNR 185.57 0.0010332000000000002 27178000.0 59445.0 47582.0 70354.0 85957.0 64575.0 69306.0 53426.0 69224.0 53950.0 52899.0 True False 78347.27346718837 62961.95098327585 69421.05999151302 66140.94167241156 55609.87589563651 64972.284863901084 58180.81050012395 58527.0214092706 56801.68685889208 51047.022111202474 1.5348059539401564 1.2334108510016022 1.3599433839702528 1.2956865834079019 1.089385307814708 1.272792852095532 1.1397493544947834 1.1465315504942375 1.112732623955095 1.0 15.639539181774767 -1.5228787452805561 0.18030345923233917 1.0044330718248264 2.905853979373512 0.7260365793506725 0.07695523902341574 30.57786054692666 0.3449510835149946 0.16907101464011517 15.934316503649645 0.029999999999984903 1.5228787452805561 1.9014209075486856 T(ph)CSFGGFDLTNR ddPTM_PC-9_Lapatinib_30min_R1 1 TCSFGGFDLTNR 12 0 O94885;A0A1B0GWB9 O94885 SASH1 SAM and SH3 domain-containing protein 1 1 T(0.513)CS(0.487)FGGFDLTNR 126.32 0.00065302 15575000.0 31381.0 34911.0 34057.0 29847.0 31648.0 30517.0 28966.0 31691.0 34295.0 28719.0 True False 30933.501185429413 34830.16572442545 31256.964923821783 32042.047946673218 29786.526862361967 29211.85904860154 30465.717748273506 33163.479553683464 30432.33595763985 33683.04088433791 0.9183702056963927 1.0340564512576695 0.9279733688877178 0.9512813304683625 0.8843182230679248 0.8672571799235798 0.9044824026692788 0.9845749873819726 0.903491346346654 1.0 15.039734769459617 -5.480818470064796 24.381710004811524 0.9233116717368511 0.9774137754455099 0.1371592686135118 0.04745641469911082 602.9579419433585 349524.0058074602 0.012264111080393086 0.025525582312683627 3.3050766044520595e-06 5.480818470064796 0.054102103708658755 T(ph)CSLPDLSK ddPTM_PC-9_AZD4547_30min_R2 2 TCSLPDLSK 9 0 Q96PY6-4;Q96PY6-2;Q96PY6-6;Q96PY6;Q96PY6-3 Q96PY6-4 NEK1 Serine/threonine-protein kinase Nek1 1 T(0.762)CS(0.236)LPDLS(0.002)K;T(0.609)CS(0.39)LPDLS(0.002)K 108.31 0.0059756 98835000.0 531060.0 551940.0 691860.0 853630.0 780930.0 701620.0 591470.0 680760.0 599050.0 662060.0 True False 699926.0332657922 730343.8112250281 682685.4843467064 656838.7919520307 672511.3493330155 657747.5904858202 644109.6841707833 575564.1843085503 630714.5600151869 638881.4809153815 1.0955491028836004 1.143160090003862 1.0685635829803097 1.0281074214436772 1.0526386652645645 1.0295299052077822 1.0081833695475269 0.9008935170321248 0.9872168451517908 1.0 19.28518879566454 -6.27386918394069 0.5934253381248181 0.9608424160085559 1.129625894670606 0.6885533187904123 0.0348343023667282 0.5635869306889152 0.412385308120761 0.026114228376371344 0.051370033614736785 5.32268562455285e-07 6.27386918394069 0.16878347866205 T(ph)CSLPDLSK ddPTM_PC-9_Lapatinib_30min_R1 2 TCSLPDLSK 9 0 Q96PY6-4;Q96PY6-2;Q96PY6-6;Q96PY6;Q96PY6-3 Q96PY6-4 NEK1 Serine/threonine-protein kinase Nek1 1 T(0.823)CS(0.174)LPDLS(0.003)K;T(0.767)CS(0.216)LPDLS(0.017)K 118.23 0.004425899999999999 65330000.0 542640.0 503010.0 542754.0 469813.0 541093.0 535392.0 482929.0 473124.0 486777.0 422969.0 True False 534901.8540920115 501845.3112498428 498130.861211028 504364.6152702252 509266.9735697679 512494.5322197094 507932.70063025516 495107.0682640785 431951.048270945 496078.6280792341 1.078260226938413 1.0116245345882702 1.0041369109968312 1.016702971508919 1.0265851918305728 1.033091335145874 1.0238955517937123 0.9980415205167831 0.8707310168620153 1.0 18.920209279221794 -8.047503192140056 7.4975221670272365 0.9343672778568763 1.024978349012935 0.52661779686124 0.034569704803322054 0.2005831892429698 27.491645943264704 0.021543467169978483 0.008225851737676027 8.963895973061282e-09 8.047503192140056 0.0906110711560586 T(ph)CSPASLSQASADLEATLR ddPTM_PC-9_AZD4547_30min_R2 1 TCSPASLSQASADLEATLR 19 0 A0A3B3IUA7;Q14258 A0A3B3IUA7 TRIM25 E3 ubiquitin/ISG15 ligase TRIM25 1 T(0.996)CS(0.004)PASLSQASADLEATLR 154.46 2.5638000000000004e-15 0.0 3897.1 5433.1 4802.8 8780.1 8148.9 6133.9 5441.2 8226.8 4215.3 6792.5 True False 5136.296735284379 7189.243324938762 4739.111733906227 6755.983596192756 7017.565895252841 5750.346263334823 5925.456258998882 6955.537093057138 4438.112152294492 6554.696642476094 0.7836055603244665 1.0968079404850937 0.7230100784825926 1.0307088130383137 1.070616426361708 0.8772864065243116 0.9040016010200114 1.0611531658053397 0.677088871441342 1.0 12.678313297371103 -4.457254255486588 10.77723144203001 0.9373578004750699 0.000134924303224516 0.1014885535666259 0.13767804855517446 24913.450424259678 176220.0839120237 0.03213363589741725 463519.2956991433 3.489359728853689e-05 4.457254255486588 -0.9372228761718454 T(ph)CSPESQQIYGDIK ddPTM_PC-9_AZD4547_30min_R2 1 TCSPESQQIYGDIK 14 0 Q4VC44-2;Q4VC44;Q4VC44-4;Q4VC44-3;I3L287;J3KNW1;Q4VC44-5 Q4VC44-2 FLYWCH1 FLYWCH-type zinc finger-containing protein 1 1 T(0.474)CS(0.474)PES(0.053)QQIYGDIK 86.777 0.015571000000000002 8240000.0 36204.0 34177.0 48941.0 46248.0 34463.0 46776.0 40732.0 55622.0 46043.0 42730.0 True False 47716.118910019155 45224.04688233829 48292.01036251867 35586.23812447725 29678.40732468172 43851.08932551067 44357.06909166039 47026.89796640546 48476.73898135252 41234.03570599976 1.1572022503505814 1.0967649929972283 1.1711686604445544 0.8630306860625643 0.7197550959185729 1.063468287173504 1.075739212332452 1.1404873949692682 1.1756486638124268 1.0 15.33154804883024 -9.758621591331682 14.361399866439987 1.0000043022135066 1.0447120606494589 0.009887028024010425 0.1405673368464539 0.0 0.0 0.15075724171772972 0.03656400184876312 1.7433252027273002e-10 9.758621591331682 0.044707758435952316 T(ph)CSVSTLSASVHNGAQVK ddPTM_PC-9_Lapatinib_30min_R1 1 TCSVSTLSASVHNGAQVK 18 0 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 T(0.942)CS(0.036)VS(0.022)TLSASVHNGAQVK 82.65100000000001 0.015913999999999998 0.0 12227.0 7289.0 14669.0 7409.5 14566.0 14670.0 10306.0 11951.0 19970.0 8792.0 True False 12052.640737842816 7272.122768334828 13462.971443977494 7954.4193473674195 13709.256517857835 14042.59829744027 10839.594252354718 12506.287089270489 17720.768306577284 10311.685485396396 1.168833238262745 0.7052312426163255 1.305603382011991 0.7713985612374057 1.3294874574358522 1.3618140620490864 1.051195196721812 1.212826662235008 1.7185132664949654 1.0 13.331992545687225 -6.285185854521677 24.67993649032376 1.2823673175157184 0.9902881119459176 0.2540742026033822 0.24438398490346275 925.0403176000804 961400.2221975619 0.07282868059167899 0.08262701619163991 5.185780681038966e-07 6.285185854521677 -0.2920792055698008 T(ph)CT(ph)GT(ph)S(ph)KR ddPTM_PC-9_Lapatinib_30min_R1 1 TCTGTSKR 8 1 B1B0D4;Q86TH1 B1B0D4 ADAMTSL2 ADAMTS-like protein 2 4 T(1)CT(1)GT(1)S(1)KR 40.589 0.035564 14232000.0 48993.0 80615.0 40002.0 42308.0 53445.0 50358.0 65003.0 57684.0 39599.0 48408.0 True False 48294.350835784186 80428.34092047077 36713.1899721854 45419.471455350664 50301.47017691282 48204.30573023152 68368.53727787828 60364.2092257952 35138.94362404375 56775.25830039455 0.8506231813206665 1.416608982999763 0.6466406507203908 0.7999870509622152 0.8859751885367162 0.8490371893190759 1.2041959706487706 1.063213291015106 0.6189129680066917 1.0 15.792974744072112 -5.26676030395314 24.999190437564685 0.89308199604934 1.133616074345478 0.18289882096671717 0.2106886744377139 695.473232077551 3267540.653465712 0.05484727995405332 0.11972960344664947 5.4105285874230215e-06 5.26676030395314 0.24053407829613793 T(ph)DGSSVGGT(ph)FS(ph)RATTLS(ph)RGQS(ph)RK ddPTM_PC-9_Lapatinib_30min_R1 1 TDGSSVGGTFSRATTLSRGQSRK 23 3 P83369 P83369 LSM11 U7 snRNA-associated Sm-like protein LSm11 5 T(0.509)DGS(0.509)S(0.562)VGGT(0.603)FS(0.674)RAT(0.131)T(0.088)LS(0.933)RGQS(0.992)RK 43.11600000000001 0.041614 0.0 2464.9 1023.7 2684.7 2032.8 2091.7 2517.3 1048.3 2027.6 2029.5 2655.8 True False 2429.750073992702 1021.3296855459404 2463.974329241691 2182.2988932220105 1968.6703184404232 2409.64094711291 1102.5758446287055 2121.8096981177177 1800.9163384175565 3114.851491368944 0.780053264409358 0.3278903306870264 0.7910407080623932 0.7006108956619673 0.6320270240476902 0.7735973781703147 0.3539738082807072 0.681191287609415 0.5781708512934827 1.0 11.604947665319711 -10.722226903616566 5.198407719704208 1.0000260889393537 0.62105876697599 0.3398272338711539 0.15704374639034854 4.520140547803913e-05 6.961916928562011e-06 0.14474680076775948 0.03510384252608378 1.895715217796455e-11 10.722226903616566 -0.3789673219633637 T(ph)DIPRYIIRQLGLTR ddPTM_PC-9_AZD4547_30min_R2 1 TDIPRYIIRQLGLTR 15 2 Q9Y2H9;K7EJZ9;K7EME4 Q9Y2H9 MAST1 Microtubule-associated serine/threonine-protein kinase 1 1 T(0.999)DIPRYIIRQLGLT(0.001)R 82.494 0.032576999999999995 23949000.0 33492.0 23411.0 50324.0 82520.0 58575.0 40518.0 45844.0 51483.0 36209.0 52947.0 True False 44141.75932312343 30978.14792294293 49656.67087888253 63496.28892129094 50442.87232809772 37984.40305479392 49924.02718840417 43527.485311647375 38122.933817861434 51093.34164581255 0.8639434787632675 0.6063049885773483 0.9718814483325584 1.2427507553030621 0.9872690002892356 0.7434315672305807 0.9771141518690585 0.8519208943777267 0.7461428943547259 1.0 15.640847674617383 -5.280001608320225 24.299785035654793 0.9415721017017288 0.7351242194382721 0.23634630896448194 0.14733326384802872 750.6917876751019 982729.0492444575 0.04112749609642874 0.08588466343524898 5.248055167369611e-06 5.280001608320225 -0.20644788226345667 T(ph)DSIGEK ddPTM_PC-9_Lapatinib_30min_R1 1 TDSIGEK 7 0 A0A286YFF8;Q7Z3U7-2;Q7Z3U7-6;Q7Z3U7-5;Q7Z3U7;Q7Z3U7-3 A0A286YFF8 MON2 Protein MON2 homolog 1 T(0.946)DS(0.054)IGEK 101.46 0.027364 26784000.0 173160.0 193240.0 136630.0 159420.0 197920.0 155010.0 215780.0 193640.0 204310.0 161820.0 True False 170690.7066463454 192792.56465262984 125396.80880705187 171144.27860953045 186278.73472569147 148380.5836459588 226952.03258035146 202637.22131757502 181298.4563203205 189790.37138840352 0.8993644166332817 1.0158184698320778 0.6607121735929845 0.9017542742423214 0.9814972875756403 0.7818130211795616 1.1958037223916753 1.0676896822277702 0.9552563441129243 1.0 17.534047276582115 -7.253596996505201 24.998043664968932 1.0603282458401195 0.8764845982833821 0.3953925120237425 0.1096410071544756 623.1911895772857 1986461.5083983503 0.042689494648205546 0.03243264374733752 5.5770302932626076e-08 7.253596996505201 -0.18384364755673743 T(ph)DSPSCEYSR ddPTM_PC-9_Lapatinib_30min_R1 1 TDSPSCEYSR 10 0 Q9HAV4 Q9HAV4 XPO5 Exportin-5 1 T(0.692)DS(0.268)PS(0.04)CEYSR 121.36 0.0015375999999999999 5378700.0 95985.0 121470.0 110400.0 110080.0 140690.0 134550.0 142140.0 127940.0 135000.0 112880.0 True False 94616.236298507 121188.74367809475 101323.33815632403 118175.6504161151 132414.8908071824 128795.6101513693 149499.31370363844 133884.55946793268 119794.878386977 132391.1575968548 0.7146718709615301 0.9153839718444595 0.7653331234164776 0.8926249498925944 1.0001792658267998 0.9728414834438238 1.1292243108779196 1.011280223680991 0.9048555852330046 1.0 17.014447242222623 -6.106117458939238 2.5634767852960625 1.0103779862618332 0.8094704036531408 0.6289598979396026 0.07042703251744345 0.1898214201885043 2.4388913792185827 0.02212340533842273 0.03107822580232942 7.832177856604356e-07 6.106117458939238 -0.20090758260869235 T(ph)DSPWIKPAR ddPTM_PC-9_Lapatinib_30min_R1 1 TDSPWIKPAR 10 1 A0A0D9SER9;A0A1W2PPZ7;A0A0D9SEQ1;A0A1B0GVZ8;A0A1B0GUD1;A0A0C4DGF8;A0A1B0GU48;A0A1B0GV09;Q9H9B1-4;Q9H9B1-3;Q9H9B1 A0A0D9SER9 EHMT1 Histone-lysine N-methyltransferase EHMT1 1 T(0.581)DS(0.419)PWIKPAR 64.22399999999999 0.037464 3484400.0 38238.0 37749.0 33545.0 36955.0 33735.0 35297.0 26414.0 32510.0 27756.0 25056.0 True False 37692.71910800963 37661.59450979165 30787.05958744462 39672.79397826612 31750.773625561866 33787.42959132578 27781.58767530541 34020.53328358995 24629.826996362495 29386.896214978624 1.2826369560184274 1.2815778241526363 1.0476458405890556 1.3500164729218573 1.080439846157634 1.149744748276757 0.945373321226929 1.1576769807438714 0.8381227747287096 1.0 14.842885372029034 -6.923408181333399 0.6724849901576909 0.9595192884995108 1.2523138151503637 0.4969955615077817 0.10952320116971352 0.6359372431610227 0.6145568337140619 0.0830240294928348 0.07410139186912419 1.19286643536925e-07 6.923408181333399 0.2927945266508528 T(ph)DSQTIGDFATR ddPTM_PC-9_AZD4547_30min_R2 1 TDSQTIGDFATR 12 0 Q13480-2 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 T(0.997)DS(0.003)QTIGDFATR 172.58 0.0028324 18149000.0 24742.0 27301.0 36837.0 39382.0 39493.0 27930.0 38415.0 33816.0 40515.0 36673.0 True False 32609.44133442972 36125.5143498469 36348.51731113179 30303.08834583468 34010.07864880177 26183.53268474244 41833.86058028418 28590.514214374984 42656.54018698821 35389.08943239246 0.9214546589769428 1.0208093773890767 1.0271108382308687 0.8562833582854934 0.9610328831369013 0.7398758517017971 1.1821118104833934 0.8078906429337348 1.2053585122182795 1.0 15.11101702098843 -8.269029373337203 24.99400060600748 1.102679237757205 0.9445644120924912 0.2100664192296755 0.12622123332185495 981.9546514129354 3233552.4830998955 0.10598515164422956 0.029475046205939655 5.382333780814618e-09 8.269029373337203 -0.1581148256647138 T(ph)DSQTIGDFATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TDSQTIGDFATR 12 0 Q13480-2 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 T(0.94)DS(0.059)QT(0.001)IGDFATR;T(0.796)DS(0.202)QT(0.002)IGDFAT(0.001)R 154.13 0.00045195 21540500.0 41697.0 43487.0 35144.0 50289.0 65890.0 59783.0 52541.0 65780.0 52557.0 44134.0 True False 48755.478546710416 47804.10196442928 35981.96624436221 47471.47036913776 52979.3274953226 56647.874238043325 47563.93611610111 64053.34469967114 53325.54669692461 52135.14483544823 0.9351748940296436 0.9169266166865209 0.6901671867975133 0.9105464369374975 1.0161921993798775 1.0865582979933865 0.91232001495776 1.2286020284750294 1.0228330019075154 1.0 15.669968615511435 -6.229216344406649 3.243724645469483 1.054237830052903 0.8485702174841209 0.4620343382677258 0.0971514565370805 0.22061831722173 4.770334397974013 0.03063362821207894 0.03901383437068177 5.899071438925732e-07 6.229216344406649 -0.20566761256878208 T(ph)DSQTIGDFATR ddPTM_PC-9_Lapatinib_30min_R1 2 TDSQTIGDFATR 12 0 Q13480-2 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 T(0.987)DS(0.012)QTIGDFATR;T(0.998)DS(0.002)QTIGDFATR 214.58 2.4168000000000004e-10 36112000.0 52754.0 57827.0 52374.0 53856.0 53855.0 52665.0 54489.0 53662.0 52302.0 43369.0 True False 52001.71828610126 57693.10513438033 48068.01188948649 57816.74989834937 50687.35478300382 50412.64071811119 57310.17380327536 56155.33242276231 46411.197995523515 50865.27386443998 1.0223422452160584 1.1342336480510664 0.945006450129249 1.1366644766808025 0.9965021503293126 0.9911013327572935 1.1267053030327046 1.1040013776868824 0.9124338565287796 1.0 15.634393432289622 -8.26266973802662 24.999307436988676 0.9562169269541446 1.0566628105632128 0.2657475480989473 0.06705294073513571 145.7522708692077 2961303.778158094 0.05186357710799593 0.01629020925827687 5.461730439374011e-09 8.26266973802662 0.10044588360906814 T(ph)DSSPNQAR ddPTM_PC-9_Lapatinib_30min_R1 1 TDSSPNQAR 9 0 A6NLN1;P26599;P26599-2;P26599-3;K7ES59;A0A087WU68 A6NLN1 PTBP1 Polypyrimidine tract-binding protein 1 1 T(0.81)DS(0.095)S(0.095)PNQAR 83.206 0.035835000000000006 2127000.0 4303.7 7756.2 5363.1 7131.8 8856.2 3830.1 13859.0 13805.0 9385.5 9582.9 True False 4242.328448798079 7738.240995439504 4922.166620164683 7656.296362987374 8335.295727959117 3666.29555139918 14576.551207392196 14446.430697630245 8328.406156303512 11239.291496588381 0.3774551492045395 0.688499003499322 0.43794278506423445 0.6812080961964013 0.7416211004483019 0.3262034401823337 1.2969279435288978 1.285350655956861 0.7410081105941196 1.0 13.456263473242181 -7.264053213236695 24.994702796584946 1.1046009065083506 0.5594572570668368 0.6457773461341828 0.1948737923097065 145.01807663665213 1386718.8164371424 0.07743334931796826 0.05488864167088974 5.444359401055174e-08 7.264053213236695 -0.5451436494415138 T(ph)DSVKTPESEGNPLLEQLEKK ddPTM_PC-9_AZD4547_30min_R2 1 TDSVKTPESEGNPLLEQLEKK 21 2 Q8WYK2;Q8WYK2-2 Q8WYK2 JDP2 Jun dimerization protein 2 1 T(0.362)DS(0.318)VKT(0.318)PES(0.003)EGNPLLEQLEKK 67.995 0.0016539999999999999 9632900.0 36832.0 19204.0 27476.0 54383.0 55382.0 41875.0 36416.0 34862.0 35606.0 53814.0 True False 48543.809846807664 25411.31744531188 27111.650287500535 41845.839558974345 47693.16526290577 39256.54963027534 39656.95345286028 29474.878949063797 37488.0604689103 51929.988239706814 0.9347933918785292 0.48933801656211096 0.5220808093072197 0.8058126138179653 0.9184127876701217 0.7559514446463693 0.7636618993596787 0.5675887853663455 0.7218961863782226 1.0 15.66428027825614 -5.783606752504042 24.94578177085695 0.7752327775034527 0.6327974086426706 0.14100153112092584 0.15571217087918995 437.199468982599 491995.4516462258 0.044534349813798446 0.06611285327683987 1.6458613528139444e-06 5.783606752504042 -0.142435368860782 T(ph)DSVKTPESEGNPLLEQLEKK ddPTM_PC-9_Lapatinib_30min_R1 2 TDSVKTPESEGNPLLEQLEKK 21 2 Q8WYK2;Q8WYK2-2 Q8WYK2 JDP2 Jun dimerization protein 2 1 T(0.361)DS(0.319)VKT(0.319)PESEGNPLLEQLEKK;T(0.367)DS(0.316)VKT(0.316)PES(0.001)EGNPLLEQLEKK 80.60300000000001 0.00040241 14006800.0 141688.0 53414.0 57672.0 57694.0 60823.0 62182.0 46351.0 44445.0 62075.0 47924.0 True False 139667.5031376032 53290.323164746405 52930.43078035792 61937.00922154205 57245.51072261888 59522.62081332177 48750.8279828152 46510.07695444958 55083.459821271135 56207.59954528395 2.484850879018225 0.9480981859368105 0.9416952726777496 1.1019330076823894 1.0184656734272868 1.0589781683412234 0.8673351713506078 0.827469547369275 0.9800002182426035 1.0 15.77847758268389 -4.76093129460213 24.9998924993267 0.9702437350524797 2.484852596069441 0.971344825138167 0.07797563450948693 1.9877655643248848 97712.45299718245 0.021430830430953597 0.12311896201973338 1.734078307287147e-05 4.76093129460213 1.5146088610169612 T(ph)DSYSAGQSVEILDGVELGEPAHKK ddPTM_PC-9_AZD4547_30min_R2 1 TDSYSAGQSVEILDGVELGEPAHKK 25 1 B1AKQ2;B1AKP8;P42345 B1AKQ2 MTOR Serine/threonine-protein kinase mTOR 1 T(0.503)DS(0.379)Y(0.051)S(0.067)AGQSVEILDGVELGEPAHKK 153.36 5.0069e-07 5648600.0 48870.0 53392.0 62937.0 69064.0 63270.0 64821.0 72602.0 69077.0 62241.0 64125.0 True False 64409.64344085279 70649.91986253332 62102.41425769474 53142.36182816324 54486.05261969682 60767.73262290329 79063.43735128963 58402.736881546676 65530.93219248014 61880.00326813091 1.0408797679237467 1.1417245657923074 1.0035942304107532 0.8587970106900805 0.8805114696520696 0.9820253622093705 1.2776896117587704 0.943806299241502 1.0590001411042187 1.0 15.917185652530906 -9.270803247743235 15.631326723606259 0.9999995783962117 1.0191833507677468 0.0026849064192066008 0.11668635440410766 0.0 0.0 0.12041495812900672 0.029204917133542514 5.360394491881804e-10 9.270803247743235 0.019183772371535124 T(ph)EAPGTPEGPEPERPSPGDGNPR ddPTM_PC-9_Lapatinib_30min_R1 1 TEAPGTPEGPEPERPSPGDGNPR 23 1 A0A0G2JNW7;Q9Y666-2;Q9Y666 A0A0G2JNW7 SLC12A7 Solute carrier family 12 member 7 1 T(0.542)EAPGT(0.458)PEGPEPERPSPGDGNPR 86.91799999999999 2.1266999999999998e-05 22210000.0 32515.0 69543.0 25427.0 14564.0 22410.0 18148.0 16832.0 12683.0 30875.0 11908.0 True False 32051.33013747926 69381.97745620909 23336.49021105842 15635.085144079776 21091.887859755177 17371.85234505425 17703.47860039147 13272.298481567868 27397.532371836427 13966.281933587381 2.294907856642885 4.967820196250873 1.6709164487748678 1.1194880082206493 1.5102006360784894 1.2438423073271092 1.267587084706957 0.9503100785649645 1.9616912004295401 1.0 13.76966038097603 -5.4075954245483455 6.513851235555974 1.3046832590767237 3.6142867596786377 0.6632444424157393 0.6571732928468177 0.11840060738573126 5.92161555993254 0.15626123431133795 0.32855558137464563 3.912051608554936e-06 5.4075954245483455 2.3096035006019138 T(ph)EEPDRDER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEEPDRDER 9 1 O95232;J3KPP4;H0YA81 O95232 LUC7L3 Luc7-like protein 3 1 T(1)EEPDRDER 62.633 0.043864999999999994 1855700.0 4215.0 5400.4 6689.1 7042.5 5876.5 7476.5 6353.3 5993.0 4886.3 4852.9 True False 4928.516249955257 5936.516021999763 6848.5935125530195 6647.931557093063 4725.042009808217 7084.419178373965 5751.469430091268 5835.690100108375 4957.7528935286 5732.692354464738 0.8597210429610491 1.0355546146438999 1.194655685163219 1.1596525935872903 0.8242273817691015 1.2357926677953466 1.0032754375196684 1.0179667317335492 0.8648210277091533 1.0 12.484997143395598 -7.993174230390517 3.0686696975313046 0.9330036498857166 1.053177937498749 0.099107213371872 0.12930616943301557 0.5746065772418502 10.733257460393611 0.09376990587076442 0.03473438352801471 1.0158410756847242e-08 7.993174230390517 0.1201742876130325 T(ph)EGSSPPDSK ddPTM_PC-9_AZD4547_30min_R2 1 TEGSSPPDSK 10 0 Q96JN0-3;A0A1P0AZG4 Q96JN0-3 LCOR Ligand-dependent corepressor 1 T(0.924)EGS(0.075)S(0.001)PPDSK 100.82 0.0093906 4876100.0 20582.0 20572.0 20842.0 27722.0 30583.0 27747.0 24458.0 25534.0 22258.0 24811.0 True False 27126.647867805048 27221.49669261384 20565.621462079114 21331.121200630478 26337.078351006607 26011.97570367164 26634.714618575814 21588.307012948047 23434.51243939239 23942.374441880642 1.1329973947928236 1.1369589410897054 0.8589633209522101 0.8909359116578475 1.1000194828185914 1.0864409362076803 1.112450842468893 0.9016777790921691 0.9787881522059948 1.0 14.547278615609345 -5.189971926982388 24.910285303243526 0.9956910623494319 1.1349790020504515 0.3151135163521369 0.0845999717069144 200.17650949755188 69770.74619352861 0.02365073310699293 0.06257395343562507 6.4569596580343965e-06 5.189971926982388 0.1392879397010196 T(ph)EGTPPPPGQPAK ddPTM_PC-9_AZD4547_30min_R2 1 TEGTPPPPGQPAK 13 0 F8VWT9;J3KPF0;Q9Y4D8-2;Q9Y4D8-4;Q9Y4D8;A0A494C150 F8VWT9 HECTD4 Probable E3 ubiquitin-protein ligase HECTD4 1 T(0.624)EGT(0.376)PPPPGQPAK 143.55 0.00021156 12269000.0 110990.0 110990.0 141190.0 193600.0 147420.0 136050.0 116650.0 159080.0 128040.0 138060.0 True False 146282.5112645846 146865.34697225408 139317.728348093 148968.5110901833 126953.27765442879 127542.77199281081 127031.62401900665 134497.84129473535 134807.9330011592 133226.56142219325 1.0979980996508438 1.1023728707283804 1.0457203643243251 1.1181592431715177 0.9529126647059177 0.9573374155370521 0.9535007333593567 1.009542240368371 1.0118697920451059 1.0 17.02352221609437 -6.2625932971222555 24.999999057805276 0.9787934445953445 1.0886317854583494 0.8005598112556775 0.026923889040370404 47.62757314177178 1031867.2035533418 0.008622347119225066 0.010324935128430482 5.462691852369435e-07 6.2625932971222555 0.10983834086300492 T(ph)ERVRNCS(ph)SPEFS(ph)KTLQLEY(ph) ddPTM_PC-9_AZD4547_30min_R2 1 TERVRNCSSPEFSKTLQLEY 20 3 Q5JX53 Q5JX53 CPNE1 4 T(0.997)ERVRNCS(0.502)S(0.502)PEFS(0.715)KT(0.616)LQLEY(0.669) 74.222 0.010514 0.0 4321.2 5101.0 4983.5 5551.7 6076.0 3304.0 3582.6 7145.5 5216.0 4616.2 True False 5695.251713456377 6749.798494508221 4917.415533838942 4271.8413379099675 5232.452279394311 3097.400357693844 3901.4444595841755 6041.327162255045 5491.707111324949 4454.588243061928 1.2785136139859383 1.5152463316943174 1.1038990060412144 0.9589755786213034 1.1746208614329092 0.6953280951428183 0.8758260576969645 1.3562032746044443 1.2328203667035549 1.0 12.121076368003763 -5.3782316804228065 5.328919258113909 1.0406359982457132 1.3938369698156288 0.36589354967479415 0.1839106061675966 0.2404015612088879 9.463793214928081 0.052177528433662496 0.11166943540416033 4.185702134547662e-06 5.3782316804228065 0.3532009715699156 T(ph)ERVRNCS(ph)SPEFS(ph)KTLQLEY(ph) ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TERVRNCSSPEFSKTLQLEY 20 3 Q5JX53 Q5JX53 CPNE1 4 T(0.989)ERVRNCS(0.505)S(0.505)PEFS(0.581)KT(0.455)LQLEY(0.964) 54.071999999999996 0.018116 3950500.0 12696.0 25879.0 19135.0 13559.0 16699.0 12290.0 15002.0 12314.0 14302.0 11971.0 True False 14845.182042569862 28448.096091647272 19591.25096989161 12799.333188871115 13426.950824774523 11645.4907646915 13580.901954925659 11990.770547761484 14511.13969327426 14141.247537616138 1.0497788121649974 2.011710495553839 1.3853976403268737 0.9051063673713728 0.9494884230728892 0.8235122632366167 0.9603750955352459 0.8479287641253488 1.0261569677409434 1.0 13.787621779536938 -5.671657170467331 4.231046981806896 0.9208620592045138 1.5655429835310064 0.5607353978764471 0.22481462723642337 0.13244868690407383 4.336010350382425 0.05777746890500278 0.10276246410987572 2.129819649783611e-06 5.671657170467331 0.6446809243264926 T(ph)ERVRNCS(ph)SPEFS(ph)KTLQLEY(ph) ddPTM_PC-9_Lapatinib_30min_R1 1 TERVRNCSSPEFSKTLQLEY 20 3 Q5JX53 Q5JX53 CPNE1 4 T(0.984)ERVRNCS(0.508)S(0.508)PEFS(0.827)KT(0.323)LQLEY(0.85) 64.256 0.0049503 4834600.0 2252.9 2941.3 2129.7 2571.1 2758.0 2247.8 2918.8 2464.7 3150.7 3525.2 True False 2220.773232868739 2934.489600562934 1954.6042868797376 2760.1872709381696 2595.7798624366274 2151.6668338777245 3069.9211822019174 2579.218959829717 2795.834987658138 4134.526122966261 0.5371288430209444 0.7097523424178109 0.4727517081153263 0.667594589765927 0.6278300790065681 0.5204143763721196 0.7425085949147282 0.6238245649248166 0.6762165492504624 1.0 12.013506269627252 -12.470553681859391 0.25961397421865917 1.739125716510453 0.5802730556293084 0.7014796544303785 0.07671439132447909 30.683890352765342 0.7825849946005379 12.479092390523558 0.1002207040589614 3.3841243911794e-13 12.470553681859391 -1.1588526608811445 T(ph)ESGEETDLISPPQEEVK ddPTM_PC-9_AZD4547_30min_R2 1 TESGEETDLISPPQEEVK 18 0 A0A5F9UY30;A0A5H1ZRP2;O43493;O43493-5;O43493-3;O43493-7 A0A5F9UY30 TGOLN2 Trans-Golgi network integral membrane protein 2 1 T(0.5)ES(0.5)GEETDLISPPQEEVK 154.39 4.3898e-05 1712200.0 7974.9 10833.0 7573.2 6446.7 7650.2 7829.3 11060.0 8720.3 7939.8 6392.6 True False 10510.752311775263 14334.55539913891 7472.774419759027 4960.5129155221275 6588.101782064244 7339.732633320942 12044.318573940982 7372.778007558976 8359.481618577045 6168.797019756003 1.7038577016092191 2.3237197387483324 1.2113827697405095 0.8041297030256854 1.0679718851123465 1.18981587655015 1.9524582402968054 1.1951727352913608 1.3551234692607363 1.0 12.590773460771796 -5.274989601606714 24.81415232940387 1.2334896936108684 2.013788705541072 0.5020195049740983 0.3152702027063575 527.0625770784538 965195.575369933 0.0868519085750817 0.1823750762383521 5.308971554478199e-06 5.274989601606714 0.7802990119302038 T(ph)ESPATAAETASEELDNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TESPATAAETASEELDNR 18 0 Q9NTJ3;C9JWF0;C9IYK2;C9JJ64;C9JR83;Q9NTJ3-2 Q9NTJ3 SMC4 Structural maintenance of chromosomes protein 4 1 T(0.607)ES(0.393)PATAAETASEELDNR;T(0.632)ES(0.366)PAT(0.002)AAETASEELDNR 250.38 1.5549e-53 42709500.0 63316.0 60479.8 52395.0 71690.0 83526.0 62906.0 75757.0 61796.0 62895.0 51968.0 True False 74034.14825199691 66483.83484692639 53644.29550914404 67673.44172211603 67159.67989640808 59607.09862031603 68580.74852681677 60173.92047827419 63814.72038935012 61389.387021538365 1.205976339624016 1.0829858070353535 0.8738366371099784 1.1023638613360467 1.0939949583279798 0.9709674833437085 1.1171433997664013 0.9802007056555601 1.0395073722915793 1.0 15.905701644023974 -4.8528847695540875 4.095282274133258 1.025898166596092 1.209123933388842 0.3888747078589192 0.06959511177956741 0.21654148226462597 6.027020688245642 0.01705563849571786 0.09666862544153958 1.4031859595687616e-05 4.8528847695540875 0.18322576679274993 T(ph)ESPATAAETASEELDNR ddPTM_PC-9_Lapatinib_30min_R1 1 TESPATAAETASEELDNR 18 0 Q9NTJ3;C9JWF0;C9IYK2;C9JJ64;C9JR83;Q9NTJ3-2 Q9NTJ3 SMC4 Structural maintenance of chromosomes protein 4 1 T(0.968)ES(0.031)PATAAETASEELDNR 142.4 0.00045157 4042100.0 10481.0 10220.0 11062.0 10735.0 13239.0 12885.0 9621.7 9290.6 9977.8 9722.2 True False 10331.539018020001 10196.336217914924 10152.525060554854 11524.487710910205 12460.308048875457 12333.938586402035 10119.864546660327 9722.275193002792 8853.995093108 11402.669315982805 0.9060631972847419 0.8942060788891776 0.8903638945597011 1.0106833226108427 1.092753609140466 1.081671163533077 0.8874996078747626 0.8526315131646718 0.7764844220026271 1.0 13.477083972197663 -7.498102201950327 22.8238506030156 0.8627478423371386 0.9785167611647395 0.24883358983420867 0.08440153220283954 347.7683876197518 320361.8841227714 0.03896776255398143 0.02608874841338986 3.176126549005108e-08 7.498102201950327 0.11576891882760088 T(ph)ESPIKLSPATPSR ddPTM_PC-9_AZD4547_30min_R2 1 TESPIKLSPATPSR 14 1 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 T(0.999)ES(0.001)PIKLSPATPSR 143.93 1.5265e-05 0.0 8221.5 5640.3 8965.4 13939.0 11595.0 10080.0 7753.4 10112.0 7277.8 8505.2 True False 10835.76598217662 7463.416672921922 8846.512938111699 10725.578905403218 9985.234394268764 9449.69600652359 8443.437579673955 8549.422750643478 7662.48965007683 8207.435536781406 1.3202377202496955 0.9093481928033205 1.077865661992261 1.3068124455363455 1.2166083241860626 1.1513579319843608 1.0287546629924673 1.0416679744031452 0.9336033911856614 1.0 13.002715798222937 -7.380256663286127 2.512884071324749 0.9921384674133843 1.1581742294078952 0.3379263992866782 0.11230441960911872 0.40124660452316546 4.934073593346455 0.05896140110852448 0.03583211444673989 4.1662309101193433e-08 7.380256663286127 0.16603576199451087 T(ph)ESPIKLSPATPSR ddPTM_PC-9_Lapatinib_30min_R1 1 TESPIKLSPATPSR 14 1 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 T(0.816)ES(0.183)PIKLSPAT(0.001)PSR 98.421 0.031836 0.0 15517.0 11159.0 11477.0 11493.0 12321.0 7632.2 9888.1 9717.3 12541.0 6883.5 True False 15295.724734530697 11133.162021106913 10533.405362501178 12338.23355952408 11596.303004018013 7305.788597527173 10400.057435155119 10168.801232747726 11128.5005174154 8073.303803312797 1.89460536939713 1.3790094231977912 1.3047205480089705 1.5282756427995703 1.4363763939193752 0.904931707701786 1.2882034032817595 1.2595588473426533 1.3784320259134724 1.0 12.978943466871423 -1.5228787452803376 0.664219587471251 1.2340849283830526 60.16975016566714 0.5409000073624955 0.1754547971714702 200.13317848085097 1.2234944856538124 0.07415992656307442 17397.731287783958 0.029999999999999995 1.5228787452803376 58.935665237284084 T(ph)ESPQGLPTVQR ddPTM_PC-9_AZD4547_30min_R2 1 TESPQGLPTVQR 12 0 F5H212;P15822;A0A0D9SFF3;P15822-2;P15822-3 F5H212 HIVEP1 Zinc finger protein 40 1 T(0.782)ES(0.175)PQGLPT(0.042)VQR 107.93 0.0036509 8672100.0 11127.0 21492.0 26200.0 27741.0 22088.0 21170.0 13517.0 19723.0 18672.0 21077.0 True False 14665.154544022296 28438.86870103328 25852.57088122412 21345.74104417755 19021.462466632885 19846.236553383373 14719.986814101287 16675.26353945227 19658.963800356505 20339.100645339517 0.7210325962658853 1.3982362935772057 1.2710773859682905 1.0494928667885173 0.9352164974409253 0.9757676555836761 0.7237285006244468 0.8198623838007914 0.9665601317952641 1.0 14.311968267044048 -6.235684814242257 2.24406624526002 0.8798485802400272 1.1557081261301307 0.24009958875943893 0.17972978176637386 0.3838646531934931 3.7974437826374037 0.059567652080380194 0.0778133058207579 5.811860556488181e-07 6.235684814242257 0.27585954589010353 T(ph)ESPQGLPTVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TESPQGLPTVQR 12 0 F5H212;P15822;A0A0D9SFF3;P15822-2;P15822-3 F5H212 HIVEP1 Zinc finger protein 40 1 T(0.544)ES(0.359)PQGLPT(0.097)VQR 114.87 0.0018313 4630500.0 17749.0 19504.0 20391.0 20099.0 24082.0 21460.0 19092.0 18213.0 13994.0 13651.0 True False 20753.555141270666 21440.228222554524 20877.198773298143 18972.918191837187 19363.30497408347 20334.599821829095 17283.46754588992 17734.928048268626 14198.635775953011 16125.81823874345 1.2869768736081089 1.329559089971808 1.29464430667705 1.1765553791405992 1.2007641837089371 1.2609964667078872 1.0717885622923078 1.09978469220614 0.880490872819077 1.0 13.97708474560645 -7.520462061673552 0.8942990747383501 0.945189819349451 1.2775389072414203 0.8088393444333382 0.06030945005933909 0.2524922338539182 0.3740241185330965 0.051542878674685585 0.024986602582620508 3.016740392704324e-08 7.520462061673552 0.33234908789196926 T(ph)ESVPSDINNPVDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TESVPSDINNPVDR 14 0 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;A8MY87 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 T(0.754)ES(0.245)VPS(0.001)DINNPVDR 220.25 2.0096e-15 16575000.0 33166.0 31426.0 34533.0 28276.0 31958.0 30697.0 28219.0 31299.0 31124.0 19794.0 True False 38780.34874164085 34545.7655928014 35356.3976871318 26691.787392028873 25696.059312422527 29087.195281019925 25545.892032132186 30477.434414031733 31579.12961917691 23382.49551078222 1.658520525482762 1.4774199604516778 1.512088291466928 1.1415286011589592 1.0989442636939015 1.243973093787493 1.092522054386897 1.303429499215679 1.3505457364298445 1.0 14.513141290124885 -5.726647735803215 6.438073333887753 1.1845004400220565 1.5461184732614186 0.7176756758874969 0.10730225332591789 0.10121212564967409 11.910069029677445 0.029611988449662903 0.05057983558183071 1.8765159673617133e-06 5.726647735803215 0.36161803323936215 T(ph)ETPIVSK ddPTM_PC-9_AZD4547_30min_R2 1 TETPIVSK 8 0 O95292 O95292 VAPB Vesicle-associated membrane protein-associated protein B/C 1 T(0.958)ET(0.042)PIVSK 111.61 0.009152500000000001 17632000.0 80184.0 103930.0 106590.0 95817.0 118460.0 101840.0 134180.0 139030.0 132430.0 90784.0 True False 105680.84406919051 137523.34003807872 105176.5469553312 73727.87100789309 102013.87376844141 95471.92870082973 146121.760058897 117546.10809157083 139429.9794387967 87605.67979249913 1.2063241141385332 1.5697993596284334 1.200567671005465 0.8415877963908652 1.1644664365377817 1.0897915400800773 1.667948475544026 1.341763551975031 1.5915632384686411 1.0 16.418736787536126 -7.237537052969009 24.968916508784346 1.4287991699864722 1.1815469056869077 0.17204896485224286 0.23476097939786716 1289.7383864212686 1347292.0274344839 0.0915218025639932 0.0708513342817508 5.787126118635195e-08 7.237537052969009 -0.24725226429956448 T(ph)ETPIVSK ddPTM_PC-9_Lapatinib_30min_R1 1 TETPIVSK 8 0 O95292 O95292 VAPB Vesicle-associated membrane protein-associated protein B/C 1 T(0.989)ET(0.01)PIVS(0.001)K 123.86 0.008065000000000001 14551000.0 211690.0 285310.0 116680.0 86231.0 129700.0 144190.0 154120.0 111670.0 176870.0 39254.0 True False 208671.26178080877 284649.3822243935 107087.02079782487 92572.71539818354 122071.30100001094 138023.3298233067 162099.57948504837 116858.59587137763 156949.03807633073 46039.001597332805 4.532488858161898 6.1827879047855845 2.3260065831668424 2.010745502429544 2.6514758523148108 2.997965312768704 3.520918652902311 2.53825217352558 3.4090452145127172 1.0 15.490568927046638 -5.267992307681975 24.99261298598344 2.6458065561695885 5.357638437124039 0.6732834630121217 0.7784580400357817 257.5291691759651 982209.3308203967 0.1958645143227418 0.4233596950958863 5.395201785288769e-06 5.267992307681975 2.7118318809544504 T(ph)ETPPPLASLNVSK ddPTM_PC-9_AZD4547_30min_R2 1 TETPPPLASLNVSK 14 0 K7ELG9;Q3MHD2;Q3MHD2-2 K7ELG9 LSM12 Protein LSM12 homolog 1 T(0.611)ET(0.385)PPPLAS(0.004)LNVSK 96.37100000000001 0.0072528 12663000.0 24645.0 25920.0 19020.0 18103.0 19863.0 21968.0 32759.0 27371.0 27072.0 23166.0 True False 32481.597352155066 34298.133106773814 18767.782372552767 13929.633038561908 17105.36531033725 20594.33748723314 35674.48753740801 23141.440873008578 28502.970651416614 22354.965391181606 1.452992513464956 1.5342512281545937 0.8395352908913972 0.6231113667506168 0.7651707354950693 0.9212421995230204 1.5958194035710997 1.0351812435432002 1.2750174358426973 1.0 14.448307691924779 -5.25226887308512 24.428134588385426 1.0037770701625919 1.4936219647075593 0.36335989699293303 0.2576847362002187 570.3660655225243 1519313.0310173517 0.07343618587680123 0.18825363507613685 5.594111610487285e-06 5.25226887308512 0.4898448945449674 T(ph)ETPPPLASLNVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TETPPPLASLNVSK 14 0 K7ELG9;Q3MHD2;Q3MHD2-2 K7ELG9 LSM12 Protein LSM12 homolog 1 T(0.94)ET(0.06)PPPLASLNVSK;T(0.861)ET(0.139)PPPLASLNVSK 150.05 4.7377e-05 21854200.0 92055.0 134444.0 93338.0 76732.0 106727.0 71128.0 96021.0 63345.0 77144.0 66916.0 True False 107638.09333087353 147790.7118105575 95563.53190633625 72432.95480850032 85814.61049617981 67397.92246631216 86925.19574816151 61682.26086957535 78272.08505789048 79047.34109323533 1.361691510963231 1.8696481091785269 1.2089404979937313 0.916323734698003 1.0856103356463638 0.8526273184422126 1.099659957513743 0.7803205018220906 0.9901925096451955 1.0 16.270429315173978 -5.485246653964756 4.406514892127153 0.9619494555149115 1.6120275430552797 0.7575957561388309 0.146829309540963 0.08553718507780445 3.74381037311717 0.036602126707087596 0.07585709793817869 3.2715483721739616e-06 5.485246653964756 0.6500780875403682 T(ph)ETPPPLASLNVSK ddPTM_PC-9_Lapatinib_30min_R1 1 TETPPPLASLNVSK 14 0 K7ELG9;Q3MHD2;Q3MHD2-2 K7ELG9 LSM12 Protein LSM12 homolog 1 T(0.56)ET(0.439)PPPLAS(0.001)LNVSK 125.22 8.7266e-05 42629000.0 29841.0 40888.0 34426.0 36898.0 40349.0 41700.0 42219.0 41521.0 32792.0 37864.0 True False 29415.461867830803 40793.32634815125 31595.62716820298 39611.60200811972 37975.75114918616 39916.58820744778 44404.89324084646 43450.21723986276 29098.619644931507 44408.74194939138 0.6623799859350428 0.9185877500119167 0.7114731420270733 0.891977576245269 0.8551413411454818 0.8988452826008244 0.9999133344387621 0.9784158553597181 0.6552453045864837 1.0 15.438556081476356 -5.839188576989543 8.823222413039215 0.8991774870677942 0.7798054956385347 0.22423595026236998 0.11215467408797619 0.4593614160343791 47.137771933325006 0.03078589475086864 0.04580599180375063 1.448142912262199e-06 5.839188576989543 -0.11937199142925947 T(ph)ETQEKNPLPSKETIEQEK ddPTM_PC-9_Lapatinib_30min_R1 1 TETQEKNPLPSKETIEQEK 19 2 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 1 T(0.5)ET(0.5)QEKNPLPSKETIEQEK 112.57 0.00050721 0.0 15608.0 14072.0 11242.0 18121.0 11477.0 13777.0 10441.0 11490.0 14581.0 25502.0 True False 15385.427057843353 14039.4171485811 10317.726155374934 19453.678789883917 10801.945424650172 13187.789825755584 10981.583891794646 12023.867346307235 12938.734235263053 29909.98672072099 0.514390969193733 0.46938894622961824 0.3449592355795677 0.650407469970785 0.3611484527061598 0.44091593717155914 0.3671544221778889 0.40200176143767263 0.4325890999576867 1.0 14.86833964948668 -10.796499747880993 4.375551855300669 1.000370888559068 0.440730738484685 0.7936755275283687 0.08526236199302406 240709129.12119398 212612711.23453888 1018667.429310975 0.0207639426213782 1.5977184565746227e-11 10.796499747880993 -0.5596401500743831 T(ph)EVCSPLRDQEYGQPCSR ddPTM_PC-9_Lapatinib_30min_R1 1 TEVCSPLRDQEYGQPCSR 18 1 E9PJ09;A0A087WWZ6;Q9NQV5-2;Q9NQV5 E9PJ09 PRDM11 PR domain-containing protein 11 1 T(0.49)EVCS(0.49)PLRDQEY(0.02)GQPCSR 53.21 0.035868000000000004 5227600.0 8600.7 14719.0 16790.0 11146.0 12186.0 13804.0 11573.0 11257.0 16461.0 11292.0 True False 8478.052440824784 14684.919059832664 15409.591011274271 11965.714021966021 11469.243438597794 13213.635098695664 12172.193312876107 11780.041315698922 14606.988837985413 13243.80715435578 0.6401522116724889 1.1088140206725159 1.1635318176772291 0.9034950360199556 0.8660080371848101 0.9977217989277205 0.9190856655499375 0.8894754490459763 1.1029297442753305 1.0 13.693030288187686 -8.263617744724728 24.98801305717067 1.0514648706499916 0.9474502829858026 0.09748387115909496 0.13700971653800179 537.0222282998468 6159952.762767607 0.11232741241010949 0.0346128096472003 5.449821216047796e-09 8.263617744724728 -0.10401458766418903 T(ph)FCGTPDYIAPEIIAYQPYGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TFCGTPDYIAPEIIAYQPYGK 21 0 P17252;P05129-2;P05771;P05771-2;P05129 P17252 PRKCA;PRKCG;PRKCB Protein kinase C alpha type;Protein kinase C gamma type;Protein kinase C beta type 1 T(0.499)FCGT(0.499)PDY(0.002)IAPEIIAYQPYGK 96.48700000000001 0.00066511 1944400.0 25971.0 25268.0 18761.0 23602.0 22566.0 20850.0 21999.0 20645.0 20332.0 15036.0 True False 30367.37734936844 27776.4400496056 19208.333391488704 22279.65645871642 18144.354291386404 19756.589295672726 19915.095461032495 20103.090625185636 20629.317035635035 17761.907775089483 1.7096911961201449 1.5638207562681519 1.081434136170203 1.2543504189320778 1.0215318377473668 1.1123010853248951 1.1212250234157162 1.1318091997628537 1.161435882724659 1.0 14.116498926881814 -5.1699279685713915 3.455570098975631 1.1159919212710085 1.685832225494076 0.9018949231874112 0.06993682810758857 0.06404232828246163 1.4239324231977912 0.017564824003527366 0.05629665321909473 6.761951187956352e-06 5.1699279685713915 0.5698403042230675 T(ph)FEEALAR ddPTM_PC-9_AZD4547_30min_R2 2 TFEEALAR 8 0 F8WCC1;E7EXA6;A0A0D9SF58;Q8WVB6;Q8WVB6-2 F8WCC1 CHTF18 Chromosome transmission fidelity protein 18 homolog 1 T(1)FEEALAR;T(1)FEEALAR 104.42 0.0058668999999999995 774000.0 4871.1 3384.5 6479.200000000001 12143.099999999999 9190.900000000001 6284.8 5631.2 7555.299999999999 6332.799999999999 6067.0 True False 6420.008474825831 4478.473437495212 6393.2815745659245 9343.695904024815 7914.902181482083 5891.810462480103 6132.365890920111 6387.801988522219 6667.538879332562 5854.596176651076 1.096575798076338 0.7649500157424984 1.0920106838560786 1.5959590759288815 1.351912573073406 1.0063564223229335 1.0474447264828988 1.091074737826947 1.138855469814231 1.0 12.515353948294681 -10.657933192844823 14.452915698461785 1.0000398572676166 1.1325037277825378 0.03533732544419388 0.20636429412379625 0.0 0.0 0.22154024656124865 0.053731402170435774 2.198197993727774e-11 10.657933192844823 0.13246387051492126 T(ph)FEEALAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TFEEALAR 8 0 F8WCC1;E7EXA6;A0A0D9SF58;Q8WVB6;Q8WVB6-2 F8WCC1 CHTF18 Chromosome transmission fidelity protein 18 homolog 1 T(1)FEEALAR 92.23899999999999 0.019864 1147000.0 3406.5 2619.6 5396.4 6766.4 5993.1 6370.5 5072.1 6013.1 5053.5 4819.9 True False 3983.153168558148 2879.6565756667237 5525.070641960968 6387.300544964784 4818.795076828321 6036.41976537569 4591.633969176005 5855.262496406087 5127.397877217278 5693.709715692597 0.6995708189302425 0.5057610449879487 0.9703815118521344 1.1218170338681936 0.8463366271636753 1.0601909944124022 0.8064397727409374 1.0283739053763543 0.9005372829397167 1.0 12.475153226213243 -5.270684226746379 24.591368346975102 0.9666210781861988 0.6026659313398222 0.6772978228972693 0.10052731873095916 242.33947823141722 644626.5257408564 0.024666946319257477 0.052547228375561535 5.361863741329644e-06 5.270684226746379 -0.36395514684637664 T(ph)FEEALAR ddPTM_PC-9_Lapatinib_30min_R1 2 TFEEALAR 8 0 F8WCC1;E7EXA6;A0A0D9SF58;Q8WVB6;Q8WVB6-2 F8WCC1 CHTF18 Chromosome transmission fidelity protein 18 homolog 1 T(1)FEEALAR;T(1)FEEALAR 105.98 0.009373200000000002 1935210.0 4913.9 5643.0 5526.6 3841.4 6076.4 4886.7 4017.5299999999997 4434.9 6063.6 4649.1 True False 4843.826884901101 5629.933980204888 5072.224281292934 4123.909370534744 5718.998098662047 4677.707232454081 4225.538045474737 4640.961644398433 5380.65351546129 5452.690740463645 0.8883369909383909 1.0325056468774116 0.9302240898521307 0.7563072191004337 1.0488396226512853 0.857871362067443 0.7749454804244845 0.8511323794614858 0.9867886831600815 1.0 12.412752617296642 -5.526562459294387 24.996156405842452 0.8864220966316266 0.9656572264166716 0.06087521197774082 0.09550780104993398 228.54973887051455 1550839.838324902 0.025493386985969823 0.04443041706177813 2.974661418735599e-06 5.526562459294387 0.07923512978504499 T(ph)FLRPSPEDEAIYGPNTK ddPTM_PC-9_AZD4547_30min_R2 1 TFLRPSPEDEAIYGPNTK 18 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 T(0.606)FLRPS(0.394)PEDEAIYGPNTK 61.437 0.016914 2912300.0 26112.0 19160.0 30133.0 45689.0 36640.0 34197.0 29136.0 33003.0 29870.0 27888.0 True False 34415.07283665947 25353.095305778792 29733.416731447574 35156.10693801333 31553.168452437058 32058.656184036427 31729.04755608899 27903.144683493567 31448.867219186406 26911.64960844656 1.278816918969466 0.9420862590980451 1.1048529972728005 1.3063527301194922 1.1724724761032002 1.1912557071185415 1.1790079024412694 1.0368425975171665 1.168596785286465 1.0 14.71594320638745 -8.997784896578366 0.7456611106084498 1.0001857449670695 1.1584036970032054 0.17539351822224458 0.10094471868974274 3.047183112268318 2.845201276414745 0.1117882765166878 0.03710329307013921 1.0051134936279673e-09 8.997784896578366 0.15821795203613598 T(ph)FNWS(ph)ST(ph)LTNHR ddPTM_PC-9_Lapatinib_30min_R1 1 TFNWSSTLTNHR 12 0 F5H2M4;A0A087X0A2;A0A087WZJ7;O75437-2;O75437 F5H2M4 ZNF254 Zinc finger protein 254 3 T(0.998)FNWS(0.998)S(0.025)T(0.854)LT(0.126)NHR 54.198 0.045042 1265900.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 T(ph)FPASNYTVSSR ddPTM_PC-9_AZD4547_30min_R2 1 TFPASNYTVSSR 12 0 O95835;O95835-2;Q6PJG3 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 T(1)FPASNYTVSSR 79.744 0.036799 10492000.0 28602.0 13394.0 23719.0 80461.0 58845.0 25115.0 23643.0 35587.0 21370.0 36964.0 True False 37696.84104144204 17723.348566054327 23404.47056228072 61911.95956005807 50675.387488636945 23544.55507974603 25747.181197440023 30087.84685790642 22499.57457228032 35669.90161096597 1.0568249235050575 0.496871249025415 0.6561405976820945 1.7356919072920718 1.4206764022320109 0.6600678447766659 0.7218181165244534 0.8435079856978506 0.6307719829920498 1.0 15.122419615943823 -6.812959570555194 24.99997123389251 0.7583637444577004 1.0548554865454993 0.1626877059644738 0.3406762704100418 227.8663534158769 110569.45493804867 0.13424260202073626 0.11839098878501025 1.5382978372243983e-07 6.812959570555194 0.29649174208779894 T(ph)FPASNYTVSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TFPASNYTVSSR 12 0 O95835;O95835-2;Q6PJG3 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 T(1)FPASNYTVSSR;T(1)FPASNYTVSSR;T(1)FPASNYTVSSR;T(0.999)FPAS(0.001)NYTVSSR 136.93 0.00015866 26621400.0 20290.0 14141.4 28331.6 43644.2 45711.5 49578.2 39796.1 61955.1 47895.5 33885.6 True False 23724.69625423302 15545.26473474325 29007.132792191343 41198.95697040553 36754.65971774837 46978.23191456701 36026.32530918657 60328.8442718546 48595.8810781162 40028.79104173797 0.5926908017155779 0.38835209183645397 0.7246567292513442 1.0292331069266476 0.9182055905566655 1.1736110607383288 0.9000103268575353 1.5071363061889576 1.2140232021358162 1.0 15.288750423343156 -5.739736964548422 0.7990515197596977 1.1940610447484077 0.3866354607532577 0.6840695781116101 0.1719647875443153 0.5046800248914179 0.5637815933970071 0.07994128052846416 0.28781393545795075 1.8208033152033314e-06 5.739736964548422 -0.80742558399515 T(ph)FPASNYTVSSR ddPTM_PC-9_Lapatinib_30min_R1 1 TFPASNYTVSSR 12 0 O95835;O95835-2;Q6PJG3 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 T(1)FPASNYTVSSR 98.337 0.009022 8996400.0 56081.0 11102.0 36346.0 21597.0 20391.0 24113.0 9324.4 11033.0 27983.0 9692.6 True False 55281.274656004156 11076.29400110485 33357.77217961731 23185.315425480014 19191.641470248465 23081.74320014841 9807.171807360395 11545.63345794672 24831.259865946507 11367.95299542232 4.8629049291693045 0.9743437543738159 2.9343692917317576 2.039533013095352 1.6882231548614435 2.0304221181634925 0.8627034094273239 1.0156299434556026 2.1843211241237213 1.0 13.472684873953256 -4.753604194629048 24.991950633466693 1.679984920700018 4.862910696394065 0.6926378310122732 0.6441748799920697 167.56213788493494 534431.1599789511 0.16259451207107398 1.720585106024048 1.763582600270268e-05 4.753604194629048 3.1829257756940477 T(ph)FPAWENPVVHR ddPTM_PC-9_Lapatinib_30min_R1 1 TFPAWENPVVHR 12 0 E9PQX3 E9PQX3 TTC39A 1 T(1)FPAWENPVVHR 82.645 0.029064999999999997 6402300.0 3380.3 13745.0 9817.9 13432.0 10351.0 13953.0 12388.0 11221.0 11840.0 10608.0 True False 3332.0963021288985 13713.174296990284 9010.710160189972 14419.834087838464 9742.174530848995 13356.262716031637 13029.390025050468 11742.368624274468 10506.454519272662 12441.578665728497 0.26781941356907324 1.1022053282325432 0.7242417061599123 1.1590035698250463 0.7830336320329457 1.073518327125377 1.0472457213923465 0.9438005368739846 0.8444631345870667 1.0 13.602881934850581 -4.754283735385604 24.999934945103487 0.9613556139307884 0.26781820864543493 0.7052663038750688 0.13503637931729723 129.51764580227314 452461.7614633763 0.030994212015244972 0.30711889468388637 1.7608252795947137e-05 4.754283735385604 -0.6935374052853535 T(ph)FSATVR ddPTM_PC-9_AZD4547_30min_R2 1 TFSATVR 7 0 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 1 T(0.565)FS(0.43)AT(0.005)VR 47.574 0.033311 515860000.0 468020.0 490590.0 788770.0 1017700.0 1025800.0 981710.0 847030.0 962020.0 807080.0 984100.0 True False 616840.6245792499 649163.6234896671 778310.3944268373 783084.9883082609 883385.3765968874 920323.5185083612 922414.0290854649 813361.9140203774 849740.6011135232 949646.9585367288 0.6495473070642103 0.6835841653091125 0.8195786733483601 0.8246064300725859 0.9302250364262303 0.9691217459659421 0.9713231014889724 0.8564887263722223 0.8947963171733345 1.0 19.857031750163316 -5.449265646358484 1.0436954317261862 0.9340219217713762 0.6170504300972197 0.8564911489700741 0.04291853111687485 0.295205953440896 0.5100011466222493 0.016328342022546103 0.08188231326167614 3.5541385488590024e-06 5.449265646358484 -0.3169714916741565 T(ph)FSLDAVPPDHSPR ddPTM_PC-9_AZD4547_30min_R2 1 TFSLDAVPPDHSPR 14 0 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 T(0.636)FS(0.364)LDAVPPDHSPR 188.09 9.4575e-06 26346000.0 32780.0 20673.0 51579.0 64561.0 48125.0 44987.0 42682.0 50026.0 31627.0 39647.0 True False 43203.35813364347 27355.142967451193 50895.02875888009 49677.45890750682 41443.67444796758 42173.9557783211 46480.61531400985 42295.63118311814 33298.7386521998 38258.97059760761 1.1292347247927534 0.7149994508519723 1.330277003377154 1.298452575475547 1.0832407093190093 1.102328555095999 1.2148945616669664 1.1055088655668888 0.8703511394078652 1.0 15.22351043635669 -8.196432657915087 7.05276745615126 0.9360153832312346 1.1232692422190138 0.17795945458655438 0.16103842089386688 0.4221374652225347 39.218825743336545 0.11525321926825857 0.04265106918863261 6.361614409431578e-09 8.196432657915087 0.18725385898777924 T(ph)FSLDAVPPDHSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TFSLDAVPPDHSPR 14 0 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 T(0.5)FS(0.5)LDAVPPDHSPR;T(0.579)FS(0.421)LDAVPPDHSPR;T(0.576)FS(0.424)LDAVPPDHSPR 111.7 0.00078567 84293000.0 85607.0 76153.0 83106.0 112741.0 145588.0 159129.0 172785.0 169702.0 167235.0 120873.0 True False 100098.57428467851 83712.96656235612 85087.56222126004 106424.48728125387 117061.07651220266 150783.9951094057 156417.55394492942 165247.50231413206 169680.49549746347 142786.31806985842 0.7010375758530669 0.5862814287388475 0.5959083711342065 0.7453409312591528 0.819833987559861 1.056011508298956 1.095465980629894 1.1573062779956582 1.1883526222340648 1.0 17.123498219921238 -6.576061251096614 1.3814176917322178 1.1311884231649405 0.6270092406532637 0.9253376301363532 0.060015938962905184 0.09618919983576554 0.3806251059829768 0.02522645806102806 0.02681729719685878 2.654231193792146e-07 6.576061251096614 -0.5041791825116768 T(ph)FSLDAVPPDHSPR ddPTM_PC-9_Lapatinib_30min_R1 3 TFSLDAVPPDHSPR 14 0 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 T(0.5)FS(0.5)LDAVPPDHSPR;T(0.853)FS(0.147)LDAVPPDHSPR;T(0.578)FS(0.422)LDAVPPDHSPR 201.08 8.0382e-08 42194200.0 84297.0 92763.0 92306.0 79032.0 121332.0 131640.0 122245.0 110585.0 155306.0 119031.0 True False 83094.90932182358 92548.21297284165 84716.95699146416 84844.27692302327 114195.49030789001 126010.06406782795 128574.2479506213 115723.1828103903 137813.80283531747 139605.34975116194 0.5952129303779204 0.6629274102876661 0.6068317377698419 0.6077437367139085 0.817987924613466 0.9026162986764708 0.9209836741915485 0.8289308612933519 0.9871670611546206 1.0 17.090994701884014 -6.427923095773111 2.6039268037926244 0.9168771701789308 0.6184351718992961 0.9007555987340239 0.048383429546594484 0.08396194861507321 1.1143646593121714 0.016065176930484006 0.018227419793523825 3.7331625823596166e-07 6.427923095773111 -0.2984419982796347 T(ph)FSPRVR ddPTM_PC-9_Lapatinib_30min_R1 1 TFSPRVR 7 1 Q9Y6L7 Q9Y6L7 TLL2 Tolloid-like protein 2 1 T(0.995)FS(0.005)PRVR 70.816 0.031004000000000004 14941000.0 16453.0 13306.0 16361.0 14422.0 14832.0 13441.0 12405.0 14389.0 13603.0 12386.0 True False 16218.377202889325 13275.190774518196 15015.86173528638 15482.641990381653 13959.610920833951 12866.15976250134 13047.270201868838 15057.565469627065 12070.886894059628 14526.903596692408 1.1164373119803759 0.9138348503627979 1.033658799711819 1.0657909228437956 0.9609488235340378 0.8856780577404535 0.8981453008912055 1.0365295927932971 0.8309332276981597 1.0 13.82643960545552 -6.469391453054639 6.225008831843724 0.9296795488038323 1.0233633441197894 0.3086447663045324 0.07185030112920093 0.2918679370650339 25.689882050812574 0.021755021002010797 0.024362495167832187 3.393192879242144e-07 6.469391453054639 0.09368379531595705 T(ph)FSSEEEEANYWK ddPTM_PC-9_Lapatinib_30min_R1 1 TFSSEEEEANYWK 13 0 Q9NXR1;Q9NXR1-1;I3L464;I3L3G9;I3L2S8 Q9NXR1 NDE1 Nuclear distribution protein nudE homolog 1 1 T(0.907)FS(0.085)S(0.007)EEEEANY(0.001)WK 83.087 0.029927999999999996 0.0 3711.7 5825.7 6894.9 5597.2 7676.4 6297.0 5835.0 7081.6 7724.3 5136.3 True False 3658.770477357581 5812.2109495799405 6328.027937083677 6008.836759711843 7224.889244383069 6027.69198902395 6137.107749125728 7410.636988651816 6854.307993515014 6024.102611310455 0.6073552715533291 0.9648260205042521 1.0504515519378093 0.9974658712535955 1.1993303750865891 1.0005958360846567 1.0187588334905022 1.230164468768858 1.1378139510183343 1.0 12.556530628969394 -4.442028038107757 1.3483439464438298 1.0904243523994541 5.3742753880911415e-14 0.7593688548217691 0.0799653707622926 1.3934495393589008 1.2414587282278178 0.023550005290506007 2.592799975718314 3.6138653072543905e-05 4.442028038107757 -1.0904243523994004 T(ph)FSWASVTSK ddPTM_PC-9_AZD4547_30min_R2 1 TFSWASVTSK 10 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 1 T(0.797)FS(0.201)WAS(0.002)VTSK 130.1 0.00054861 5501600.0 20709.0 25121.0 27356.0 42674.0 31081.0 30290.0 30834.0 37778.0 24212.0 28884.0 True False 27294.031226040937 33240.8719820704 26993.24156590714 32836.16860672768 26765.93964711232 28395.9615116666 33578.16626662715 31940.27815207769 25491.796890222344 27872.779951605353 0.9792360601788096 1.1925926312260742 0.9684445402566473 1.1780729680979116 0.9602895618443942 1.0187703401300348 1.2046938383945873 1.1459308403228745 0.914576763942562 1.0 14.766569279457418 -8.267331939689983 24.99701933366284 0.9572883756475109 1.0822318743525425 0.22051563304896715 0.0930166996615132 768.2600171532335 3259008.769745329 0.07915550378265676 0.02261195877095984 5.403411718455018e-09 8.267331939689983 0.12494349870503163 T(ph)FT(ph)CS(ph)S(ph)SLIK ddPTM_PC-9_AZD4547_30min_R2 1 TFTCSSSLIK 10 0 A8MUV8 A8MUV8 ZNF727 Putative zinc finger protein 727 4 T(1)FT(1)CS(0.919)S(0.919)S(0.163)LIK 56.205 0.035123 0.0 3049.9 1995.6 7720.6 9658.7 9504.6 5405.7 3396.5 7423.9 4338.8 5371.0 True False 4019.704758139084 2640.6386739150385 7618.219799449572 7432.035940427443 8185.05035133824 5067.680724450846 3698.781920107643 6276.706839250611 4568.140110164241 5182.962924805166 0.7755611638472582 0.5094843841689844 1.4698580541623207 1.4339357715368612 1.5792222460564729 0.9777574715415018 0.7136423651432322 1.2110267679536912 0.8813761889558497 1.0 12.3395613584173 -6.966020110578856 24.999890483778508 0.9514678665653062 1.1637221131191364 0.08455561040282367 0.32392451718200244 538.4904140121521 396179.9661112834 0.12718576443317225 0.11216679527555734 1.0813838752317484e-07 6.966020110578856 0.21225424655383018 T(ph)FT(ph)VQTT(ph)WS(ph)SMK ddPTM_PC-9_AZD4547_30min_R2 1 TFTVQTTWSSMK 12 0 Q15058 Q15058 KIF14 Kinesin-like protein KIF14 4 T(0.975)FT(0.885)VQT(0.326)T(0.904)WS(0.868)S(0.043)MK 43.282 0.04438 0.0 3434.1 2804.8 3049.9 5423.7 3068.9 5294.3 4359.3 3633.8 4216.4 3487.0 True False 4526.072366282642 3711.39674914657 3009.4563332307416 4173.349760329682 2642.836208069979 4963.246584061294 4747.269254916901 3072.279706416958 4439.270296048793 3364.921191360195 1.345075295642534 1.1029669160383277 0.8943616097036244 1.2402518582144557 0.7854080549808273 1.4749963823238939 1.4108114231935172 0.9130316972371817 1.3192791282741205 1.0 11.71635700103847 -6.771562414706823 24.99999151405947 1.2298873360412446 1.0745428347695254 0.1062449043106305 0.21715620280222742 501.28191255434075 1237966.0530508023 0.07559315139311365 0.06743121086410274 1.6921450400427148e-07 6.771562414706823 -0.15534450127171917 T(ph)FWSPELK ddPTM_PC-9_AZD4547_30min_R2 1 TFWSPELK 8 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EPP6;O15083 X6RM00 ERC1;ERC2 ELKS/Rab6-interacting/CAST family member 1;ERC protein 2 1 T(0.863)FWS(0.137)PELK 114.4 0.008995600000000001 16112000.0 75208.0 83401.0 92601.0 98485.0 91754.0 95119.0 122300.0 108900.0 94181.0 76239.0 True False 99122.57957642006 110358.74225455413 91373.0502355814 75780.80482808204 79015.54088932618 89171.19389330506 133184.4630735066 92072.0072730495 99159.21538567771 73569.89581534543 1.3473252677319243 1.500052990853022 1.2419896646981867 1.03005181655124 1.0740200188355422 1.2120608967167446 1.8103119706433863 1.2514902495464026 1.3478232405624093 1.0 16.16682792786255 T(ph)FWSPELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TFWSPELK 8 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EPP6;O15083 X6RM00 ERC1;ERC2 ELKS/Rab6-interacting/CAST family member 1;ERC protein 2 1 T(1)FWSPELK;T(1)FWSPELK;T(0.988)FWS(0.012)PELK 153.05 0.00027137 23438200.0 148218.0 177392.0 140558.0 144389.0 170679.0 115403.0 161911.0 129652.0 121849.0 116783.0 True False 173308.3799610604 195002.30541711432 143909.43578918374 136299.35244545416 137235.6751794534 109351.06352462932 146573.61794587196 126248.77237764893 123630.81110933989 137954.83344628033 1.2562689949428032 1.4135228215330946 1.0431634194623716 0.9879998332826024 0.9947870020291316 0.7926584432955781 1.0624754079598653 0.9151456982245588 0.8961687533585533 1.0 17.07383647891212 -5.406443135266507 3.620672528027688 0.9490618414269569 1.3341445191085268 0.7869405030970883 0.07866798124077286 0.09673480102593292 2.265475744024042 0.02075433324256097 0.047213659516265015 3.922445018524657e-06 5.406443135266507 0.3850826776815699 T(ph)FWSPELK ddPTM_PC-9_Lapatinib_30min_R1 1 TFWSPELK 8 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EPP6;O15083 X6RM00 ERC1;ERC2 ELKS/Rab6-interacting/CAST family member 1;ERC protein 2 1 T(0.954)FWS(0.046)PELK 109.29 0.0092433 11442000.0 35580.0 32834.0 38103.0 32631.0 40320.0 30245.0 38356.0 40168.0 39858.0 31752.0 True False 35072.6226754271 32757.97489031495 34970.31842183342 35030.79259382499 37948.45687216998 28951.491854538574 40341.88600265063 42034.35192049342 35368.772316652845 37240.290893119476 0.9417923929779808 0.8796379970374324 0.9390452540287365 0.9406691449957842 1.0190161237215618 0.7774238911728709 1.0832860065038914 1.128733178833995 0.9497447916871021 1.0 15.184576721737827 -7.30666572953364 24.9999917444223 1.0511688005346187 0.9214145276483325 0.40683324993487824 0.0728384175122482 424.3425797517279 234564.36998941214 0.029460869888211668 0.01986261393258133 4.9355353914224264e-08 7.30666572953364 -0.12975427288628616 T(ph)GAFS(ph)ERQGSTIGVDFT(ph)MK ddPTM_PC-9_AZD4547_30min_R2 2 TGAFSERQGSTIGVDFTMK 19 1 C9JFM7;Q86YS6-2;Q86YS6 C9JFM7 RAB43 Ras-related protein Rab-43 3 T(1)GAFS(0.999)ERQGS(0.003)T(0.003)IGVDFT(0.995)MK;T(0.997)GAFS(0.993)ERQGS(0.013)T(0.013)IGVDFT(0.983)MK 50.534 0.025975 120586000.0 6009.4 5951.099999999999 25097.0 33493.0 28190.0 18499.4 9085.099999999999 27148.0 14461.9 15689.0 True False 7920.264196714974 7874.676694896666 24764.1973819115 25771.706311691676 24276.30509481988 17342.629593559777 9893.656299829225 22952.900398978378 15226.326509446002 15139.732885359936 0.5231442494189471 0.5201331327656017 1.6357090028885772 1.702256341432075 1.6034830520883876 1.145504331211156 0.6534894885362444 1.5160703674748282 1.0057196269406974 1.0 13.886052131216152 -5.244863129933871 24.026172443773728 1.3002678529716345 0.5216383425202861 0.47256690679678337 0.3212201393462291 443.9388012672034 643454.9599590487 0.08777841089479474 0.2306040478165135 5.690322359274005e-06 5.244863129933871 -0.7786295104513484 T(ph)GAFS(ph)ERQGSTIGVDFT(ph)MK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGAFSERQGSTIGVDFTMK 19 1 C9JFM7;Q86YS6-2;Q86YS6 C9JFM7 RAB43 Ras-related protein Rab-43 3 T(0.992)GAFS(0.981)ERQGS(0.016)T(0.016)IGVDFT(0.994)MK 40.493 0.036192 17060000.0 2437.1 2976.9 29005.0 11502.0 21761.0 22161.0 7105.6 11609.0 16808.0 7855.3 True False 2849.652895080892 3272.4269583532882 29696.589202075047 10857.580229987136 17497.08826264556 20998.838147789123 6432.506127910932 11304.276050752242 17053.785202388048 9279.403707479414 0.30709439797128407 0.3526548754114056 3.2002691270063948 1.1700730534264474 1.8855832566636261 2.2629512423156646 0.6932025301072076 1.2182114721057704 1.8378104606702585 1.0 13.179816385715139 -5.063173661606023 24.999869393428963 1.6529090972719414 0.31845846427873886 0.37923642035193406 0.6800256656135305 187.1661920259678 74067.4239928876 0.16976117602618265 0.44914699590317786 8.646221126566497e-06 5.063173661606023 -1.3344506329932024 T(ph)GARKWK ddPTM_PC-9_Lapatinib_30min_R1 1 TGARKWK 7 2 E7EQG5;Q6ZTQ4 E7EQG5 CDHR3 Cadherin-related family member 3 1 T(1)GARKWK 81.635 0.015609 0.0 188460.0 173110.0 195470.0 133860.0 180720.0 175630.0 147830.0 154300.0 140430.0 116680.0 True False 185772.52584066917 172709.1744308463 179399.21113602005 143704.51094386945 170090.4049091905 168118.71431352635 155483.91406225483 161469.34129984397 124613.2946065422 136847.982533673 1.3575101539765684 1.262051301255751 1.3109379313785414 1.050103248022011 1.2429149612588393 1.2285070718682962 1.1361798046529203 1.1799175867288552 0.9105965049640369 1.0 17.062214640523536 -2.278768429520099 0.12159599864598765 0.8907060301188693 2.1435527727673787 0.5830123883400012 0.08759296879160737 57.53655889417849 0.5759725852939521 0.6218842366007584 11.94748723917571 0.005262978192341867 2.278768429520099 1.2528467426485093 T(ph)GGSPSVR ddPTM_PC-9_Lapatinib_30min_R1 1 TGGSPSVR 8 0 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 T(0.96)GGS(0.038)PS(0.002)VR 88.177 0.027313999999999998 54288000.0 183120.0 216610.0 241670.0 176000.0 198800.0 169380.0 156590.0 210480.0 229110.0 158160.0 True False 180508.67521990518 216108.45285347823 221800.8254731781 188943.62711878863 187106.97485583797 162136.01224406474 164697.46399924555 220259.66919501757 203305.21916474286 185497.74526504733 0.9731044167786862 1.1650192973757874 1.1957063152237206 1.0185764082944386 1.0086751975798482 0.8740592076329429 0.8878677407313958 1.1873980941401787 1.0959983307303893 1.0 17.501042125354566 -5.89271360381042 8.579530765983257 1.006323120604879 1.1163726642365452 0.1735099591766026 0.10079621143946123 0.458698881735681 33.57942530177267 0.03095760808283307 0.046039943912550486 1.280225272449023e-06 5.89271360381042 0.11004954363166619 T(ph)GQPMINLY(ph)T(ph)DRETGK ddPTM_PC-9_AZD4547_30min_R2 1 TGQPMINLYTDRETGK 16 1 H3BPE7;P35637-2;P35637 H3BPE7 FUS RNA-binding protein FUS 3 T(1)GQPMINLY(0.754)T(0.781)DRET(0.466)GK 45.915 0.044933 0.0 840.9 2345.4 4509.4 13503.0 7882.2 4292.0 3796.1 6085.0 515.69 3833.1 True False 1108.2887081934339 3103.5046832032126 4449.602409610381 10390.091969270368 6787.892586675746 4023.6205615078607 4133.945545979869 5144.703069389398 542.9483205979991 3698.904335704837 0.2996262156594126 0.8390335087192328 1.2029514704284712 2.808964770723249 1.8351089865054033 1.0877871381177928 1.1176135338445117 1.3908721617178723 0.14678625650223492 1.0 11.852882273367053 -8.241316913108362 23.686954189499502 0.5733931949660448 1.3545778462220222 0.17352725086712728 0.6511900421491501 655.9044684417875 772095.3293604137 0.4801772262339399 0.18085338273289794 5.73697671106098e-09 8.241316913108362 0.7811846512559774 T(ph)GSCSELDACPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGSCSELDACPSK 13 0 A0A1B0GUA8;Q9H1H9-3;Q9H1H9-4;Q9H1H9-2;Q9H1H9;H0Y9Z7 A0A1B0GUA8 KIF13A Kinesin-like protein KIF13A 1 T(0.948)GS(0.04)CS(0.012)ELDACPSK 157.33 0.00054985 19488000.0 40458.0 43461.0 31401.0 42149.0 49471.0 38289.0 47235.0 42435.0 37854.0 34975.0 True False 47306.74031807591 47775.52085625729 32149.71892895564 39787.5281789017 39777.51268054497 36281.057436067764 42760.558848214445 41321.12621359905 38407.5431372678 41315.69063805232 1.145006644872729 1.156352952557336 0.7781479247340792 0.9630125398958438 0.9627701259799184 0.8781423443676483 1.0349714161338834 1.0001315620158535 0.9296115481582661 1.0 15.334402163778275 -5.223894108508827 24.76600095409783 0.9456925076004639 1.1506799815646567 0.5916858148474698 0.06887122345145462 344.31458224003063 227119.1688397246 0.017446377713077867 0.04615640638196699 5.971808759648649e-06 5.223894108508827 0.2049874739641928 T(ph)GSCSELDACPSK ddPTM_PC-9_Lapatinib_30min_R1 2 TGSCSELDACPSK 13 0 A0A1B0GUA8;Q9H1H9-3;Q9H1H9-4;Q9H1H9-2;Q9H1H9;H0Y9Z7 A0A1B0GUA8 KIF13A Kinesin-like protein KIF13A 1 T(0.921)GS(0.077)CS(0.001)ELDACPSK;T(0.77)GS(0.229)CSELDACPSK 219.97 1.9693000000000002e-14 76230000.0 166168.0 197762.0 157293.0 162798.0 187187.0 159262.0 183197.0 181544.0 148933.0 158831.0 True False 163798.41384852063 197304.094239461 144360.97670853857 174770.7079982074 176177.0286838018 152450.7355178549 192682.0442701945 189979.19699895612 132158.59720598254 186284.72672099582 0.8792906253331567 1.0591533600871597 0.7749480016402649 0.9381912896163875 0.9457405971218852 0.8183748512361129 1.0343416106183527 1.0198323842377781 0.7094440834321345 1.0 17.507149868592087 -8.227983284385246 24.997498869998964 0.8547214567725271 0.9326789139586471 0.07851011817281361 0.10822845186537924 1453.3344135866546 1085896.21674704 0.06973044204907279 0.026351754348246922 5.915844033035447e-09 8.227983284385246 0.07795745718612002 T(ph)GSEPALSPAVVR ddPTM_PC-9_AZD4547_30min_R2 2 TGSEPALSPAVVR 13 0 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 T(0.863)GS(0.137)EPALSPAVVR;T(0.793)GS(0.201)EPALS(0.006)PAVVR 195.72 2.6804e-06 34158000.0 52058.0 55396.0 74871.0 94004.0 106579.0 92298.0 77073.0 76264.0 80792.0 77415.0 True False 68611.36112633339 73301.67367217738 73878.16162015771 72332.83014732218 91782.34553745303 86526.59146925755 83932.34768981476 64479.15117237679 85062.50017986292 74704.72441329197 0.9184340303131563 0.981218714718062 0.98893560213727 0.9682497421067018 1.2286016213604087 1.158247917368157 1.1235212812709465 0.8631201263210098 1.138649541216004 1.0 16.18891186315433 -6.078536133448572 24.999997687159702 1.0853712308834114 0.9670087375712493 0.28146288338916636 0.09478711702053665 160.80113477083614 51185.71906770247 0.02941585054441085 0.03797571251668488 8.345721087054339e-07 6.078536133448572 -0.11836249331216209 T(ph)GSEPALSPAVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TGSEPALSPAVVR 13 0 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 T(0.755)GS(0.239)EPALS(0.006)PAVVR;T(0.989)GS(0.01)EPALS(0.001)PAVVR 176.99 0.00031436 34528000.0 77445.0 64246.0 64700.0 101793.0 90164.0 62455.0 80126.0 63996.0 62192.0 65606.0 True False 90554.9088915268 70623.91829297782 66242.69337611651 96089.8682273588 72497.01144768951 59179.749854256166 72535.88521799578 62316.17280936692 63101.440344295435 77499.84846318964 1.1684527220016172 0.9112781469053103 0.8547461019563157 1.239871691787874 0.9354471380950332 0.763611168638155 0.9359487361120246 0.8040812213841352 0.8142137255180174 1.0 16.241905869012214 -6.5202114653835785 24.912106410112695 0.8551473592915769 1.0290243162161232 0.3233435890587084 0.12178148032822272 126.55674956114817 1182042.281025717 0.03932970946978193 0.04001637189104994 3.018481612389007e-07 6.5202114653835785 0.1738769569245463 T(ph)GSEPALSPAVVR ddPTM_PC-9_Lapatinib_30min_R1 1 TGSEPALSPAVVR 13 0 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 T(0.832)GS(0.168)EPALSPAVVR 168.82 0.00064132 23728000.0 77254.0 84839.0 73165.0 71209.0 74321.0 67602.0 64367.0 58327.0 64602.0 52635.0 True False 76152.34379335154 84642.56050799262 67149.65612506722 76445.94740626054 69949.584900708 64710.82004795894 67699.60830985014 61037.08535318213 57325.84247078144 61732.88961827106 1.2335781503869983 1.3711096472461415 1.0877452285206648 1.2383341826207803 1.1331007722665398 1.0482389605946212 1.0966538052644974 0.9887287915827125 0.928611034170912 1.0 15.913751702748678 -6.420613003999929 0.5057885045364148 0.9580686331422656 1.3151070672824925 0.7168300338370281 0.06826751123195438 0.6134487601555493 0.3199453366890035 0.05647621856849162 0.10463172518892157 3.7965313986776746e-07 6.420613003999929 0.35703843414022685 T(ph)GSESSQT(ph)GTSTTSSR ddPTM_PC-9_AZD4547_30min_R2 1 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 T(0.973)GS(0.027)ES(0.029)S(0.248)QT(0.704)GT(0.015)S(0.003)T(0.001)TSSR 123.08 0.00085706 0.0 10501.0 11956.0 7730.1 7634.5 9244.9 10117.0 10679.0 10225.0 11534.0 9295.5 True False 13840.09956563118 15820.543187676982 7627.593823242388 5874.483976849195 7961.405213589929 9484.382390674513 11629.410312035778 8644.961197125154 12143.66369287231 8970.067374330003 1.5429203581277373 1.7637039419515685 0.8503385208756151 0.6548985343923323 0.8875524431815749 1.0573368063896984 1.2964685577854322 0.9637565512456219 1.353798492932652 1.0 13.130903105954532 -5.259242036592572 24.99893421360629 1.0018736586968278 1.6533121983105195 0.6271185463845312 0.19898909457680802 125.33302966851305 1425876.078494878 0.05553027865791795 0.13294707277642864 5.505008113737009e-06 5.259242036592572 0.6514385396136917 T(ph)GSESSQTGTSTTSSR ddPTM_PC-9_AZD4547_30min_R2 1 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 T(0.722)GS(0.277)ES(0.001)SQTGTSTTSSR 104.55 0.0030099 856590.0 0.0 0.0 555.81 639.13 0.0 0.0 0.0 0.0 423.91 0.0 True False 0.0 0.0 548.4395962401973 491.7884529600659 0.0 0.0 0.0 0.0 446.3170171705827 0.0 0.0 T(ph)GSESSQTGTSTTSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 T(0.761)GS(0.236)ES(0.002)SQTGTSTTSSR;T(0.974)GS(0.025)ESSQTGTSTTSSR;T(0.577)GS(0.319)ES(0.052)S(0.052)QTGTSTTSSR;T(0.65)GS(0.347)ES(0.002)SQT(0.001)GTSTTSSR;T(0.887)GS(0.113)ESSQTGTSTTSSR 276.14 5.757899999999999e-82 529173190.0 43739.9 61223.619999999995 43487.78 67050.5 69719.2 72215.59999999999 97406.8 86801.61 61206.600000000006 74274.90000000001 True False 51144.2011675962 67301.49638079117 44524.69360352405 63293.87786565394 56058.22324346487 68428.48680770182 88179.7227398381 84523.15971140785 62101.63073348906 87740.35141021523 0.5829039928103331 0.767052961369329 0.5074597136653392 0.7213770727875717 0.638910402596567 0.7798975694521209 1.005007631295761 0.9633328149808069 0.7077887167689054 1.0 16.420952864078004 -6.976524161953633 3.600296711772905 0.9155000728228526 0.6479861704382958 0.6148977774857751 0.10251462598843519 0.15788280423563775 4.3839595828974804 0.0381008368500785 0.031726802837747585 1.0555427765082324e-07 6.976524161953633 -0.26751390238455686 T(ph)GSESSQTGTSTTSSR ddPTM_PC-9_Lapatinib_30min_R1 1 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 T(0.418)GS(0.298)ES(0.096)S(0.188)QTGTSTTSSR 98.676 0.0049341 1027200.0 0.0 0.0 0.0 0.0 508.04 408.71 525.86 715.37 536.12 647.89 True False 0.0 0.0 0.0 0.0 478.1580860450699 391.2304260495441 553.0864577472588 748.6087017865809 475.7365200061199 759.87692324084 0.0 0.0 0.0 0.0 0.62925728025237 0.514860254448792 0.7278632115690138 0.9851709913676537 0.6260704930702798 1.0 9.569621954897881 -6.511013626694989 1.2783418557952213 0.8236439214716539 2.6544418902652835e-39 0.8748291287791156 0.1389936360167154 0.14722164131817933 0.49993868316768963 0.05942068915890307 0.06746708063720484 3.0830912117356793e-07 6.511013626694989 -0.8236439214716539 down T(ph)GSGSPFAGNSPAR ddPTM_PC-9_AZD4547_30min_R2 2 TGSGSPFAGNSPAR 14 0 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 T(0.795)GS(0.041)GS(0.135)PFAGNS(0.029)PAR;T(0.582)GS(0.023)GS(0.395)PFAGNSPAR 160.63 0.00077148 40633000.0 60902.0 58806.0 84024.0 129326.0 113166.0 92583.0 74374.0 103398.0 78434.0 80816.0 True False 80267.5691597056 77813.88948599303 82909.78685969362 99511.88876678233 97454.85428734978 86793.77037420364 80993.14191847056 87420.21494966719 82579.8611138154 77986.65643847582 1.0292474741884747 0.9977846600896515 1.06312785604678 1.2760117347162832 1.2496349854956603 1.1129310363840998 1.0385512806587185 1.1209637512621606 1.0588973150677794 1.0 16.250939678692966 -10.691214107288872 14.542184951701087 1.0000120006862292 1.1088369290112405 0.11457941994746668 0.08725008570623624 0.0 0.0 0.09498214041754388 0.023036553136725025 2.03603806295887e-11 10.691214107288872 0.10882492832501134 T(ph)GSGSPFAGNSPAR ddPTM_PC-9_Lapatinib_30min_R1 1 TGSGSPFAGNSPAR 14 0 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 T(0.986)GS(0.001)GS(0.013)PFAGNSPAR 137.73 0.00018519999999999998 25374000.0 36520.0 36573.0 41803.0 35858.0 33183.0 43748.0 24911.0 30826.0 33679.0 22914.0 True False 35999.218103052204 36488.31746553842 38366.11870424648 38495.116938781386 31231.241180288092 41877.00002156894 26200.769689540877 32258.28849584569 29885.71636440741 26874.654369014228 1.339523017068393 1.3577222971696519 1.4275948697774365 1.4323948658169627 1.1621076405840922 1.5582339942519234 0.9749248987458488 1.2003238461380419 1.1120409570314274 1.0 14.713958580081664 -7.270334302278127 24.995719595655 1.088516076755495 1.373297716860802 0.6523751889713232 0.1097356604144017 430.30684326648736 1209204.7374223603 0.04348474511041874 0.02980727919783696 5.36618570137053e-08 7.270334302278127 0.28478164010530693 T(ph)GSNAAQYK ddPTM_PC-9_AZD4547_30min_R2 1 TGSNAAQYK 9 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 T(0.958)GS(0.042)NAAQYK 91.31299999999999 0.019309 61128000.0 42521.0 35060.0 29852.0 41835.0 45171.0 41449.0 45532.0 32873.0 40527.0 36128.0 True False 56041.793508256655 46392.45936433214 29456.142975049694 32190.58709430688 38899.78635821599 38857.18747761867 49584.259792828285 27793.23319639075 42669.17448248971 34863.169716507364 1.607478435379369 1.3307011307800212 0.844907196177934 0.9233408022296079 1.1157845564397242 1.1145626686726702 1.42225334632584 0.797209015198378 1.2239040462888915 1.0 15.089416123034766 -4.988350501915178 4.108638117485373 1.0605685089905148 1.5761243973169503 0.5025970312968335 0.17474863293810536 0.16598333536680737 6.539950866833921 0.04487620957701619 0.18654281235573314 1.02718696150179e-05 4.988350501915178 0.5155558883264355 T(ph)GSNAAQYK ddPTM_PC-9_Lapatinib_30min_R1 2 TGSNAAQYK 9 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 T(0.962)GS(0.038)NAAQYK;T(0.961)GS(0.039)NAAQYK 118.9 0.004326699999999999 129006000.0 149514.0 160104.0 131678.0 154254.0 154207.0 131354.0 125485.0 125701.0 131048.0 126390.0 True False 147381.9029424902 159733.2890247605 120851.94313177896 165598.35373625963 145136.84744262695 125736.29562112948 131981.99929717934 131541.52735406146 116287.99424338203 148236.3430959109 0.994235960388824 1.0775582133823345 0.8152652757602508 1.1171238461347852 0.9790908518886051 0.8482150395451701 0.8903484566654832 0.8873770399810276 0.7844769495436226 1.0 17.177539670908764 -6.687524710064499 5.947252095166829 0.8757677764807054 0.9992838289580691 0.2936528834323492 0.08885128212751528 0.2523952634944116 15.274807369853006 0.02852505594047069 0.028306220068355443 2.0534081903138388e-07 6.687524710064499 0.12351605247736375 T(ph)GSNISGASSDISLDEQYK ddPTM_PC-9_AZD4547_30min_R2 1 TGSNISGASSDISLDEQYK 19 0 P22059 P22059 OSBP Oxysterol-binding protein 1 1 T(0.461)GS(0.461)NIS(0.079)GASSDISLDEQYK 231.5 1.5679e-35 12325000.0 9595.1 12184.0 18296.0 24296.0 27532.0 25448.0 33531.0 28587.0 25854.0 24580.0 True False 12646.142209521733 16122.239728893977 18053.383085605958 18694.932569458113 23709.65703691312 23856.732537104395 36515.19404184585 24169.536013908735 27220.58965801291 23719.461681569715 0.533154688723308 0.6797051276008147 0.7611211134540055 0.7881685014792845 0.999586641350119 1.005787266902492 1.5394613306177416 1.0189748965799141 1.1476057097519885 1.0 14.533783647521789 -6.2217461134287095 1.1358698098562943 1.1768225311565077 0.6223186389141728 0.6794766425125047 0.15063739162968973 0.2850801362260305 0.759909066850774 0.06356620946004844 0.0986110173844849 6.001418138900823e-07 6.2217461134287095 -0.5545038922423349 T(ph)GSNISGASSDISLDEQYK ddPTM_PC-9_Lapatinib_30min_R1 2 TGSNISGASSDISLDEQYK 19 0 P22059 P22059 OSBP Oxysterol-binding protein 1 1 T(0.766)GS(0.109)NIS(0.125)GASSDISLDEQYK;T(0.325)GS(0.325)NIS(0.322)GAS(0.022)S(0.006)DISLDEQYK 227.4 6.684399999999999e-35 35490000.0 16500.3 28380.9 29604.0 31472.1 41384.0 32386.5 33634.5 38459.0 27057.0 33535.0 True False 16265.002696215566 28315.185769767293 27170.073394744675 33786.6632218479 38949.87448407444 31001.404891618888 35375.92983512757 40245.945541482164 24009.555737158797 39331.48006742128 0.41353650227081223 0.7199115243369926 0.6907971260723026 0.8590234378144793 0.9902977059929425 0.7882084487661503 0.8994304250561337 1.023250217700766 0.610441196110649 1.0 15.26339685634012 -4.5165282998719025 0.8789835381577055 0.8849819568556292 1.9855438130733866e-12 0.5733048920187188 0.1210107427443632 2.406853464008627 1.0597929544895186 0.0407167150694235 2.290322532563358 3.04418961544789e-05 4.5165282998719025 -0.8849819568536437 T(ph)GSPGPELLFHEGQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGSPGPELLFHEGQQK 16 0 A6NHN7;A6NHB5;Q14202-2;Q14202;A6NL54;Q14202-3 A6NHN7 ZMYM3 Zinc finger MYM-type protein 3 1 T(0.739)GS(0.261)PGPELLFHEGQQK 160.47 0.00011685 16976000.0 46726.0 57254.0 36263.0 54970.0 46165.0 36354.0 58441.0 34780.0 32925.0 37056.0 True False 54635.788919432845 62937.798741495884 37127.64744819334 51890.209115144535 37119.29964822538 34447.532242440575 52905.04540380018 33867.061852456114 33406.46583701967 43773.95946486538 1.2481344979378797 1.4377908581016556 0.8481674470867407 1.1854127373785677 0.8479767446675396 0.7869412011972428 1.208596299045412 0.7736805686869401 0.7631584221626776 1.0 15.417785264828034 -5.262520281508807 24.9988894598999 0.9301574164733877 1.3429626973512914 0.5238031783588566 0.1587157385861221 69.82907790535731 1615040.7347880926 0.04100032646640816 0.0939578211792046 5.463610342804924e-06 5.262520281508807 0.4128052808779037 T(ph)GSPGPELLFHEGQQK ddPTM_PC-9_Lapatinib_30min_R1 1 TGSPGPELLFHEGQQK 16 0 A6NHN7;A6NHB5;Q14202-2;Q14202;A6NL54;Q14202-3 A6NHN7 ZMYM3 Zinc finger MYM-type protein 3 1 T(0.765)GS(0.235)PGPELLFHEGQQK 164.58 0.00012349 23230000.0 44399.0 73341.0 56889.0 61331.0 77320.0 70177.0 70718.0 77431.0 59288.0 55155.0 True False 43765.86211822056 73171.18342055747 52211.80601789052 65841.4863342184 72772.18961696874 67175.69330057708 74379.43201416847 81028.72693576278 52610.36110968223 64688.46826058214 0.6765635869119697 1.1311317981097453 0.807126948926471 1.0178241671914627 1.1249638702809168 1.0384492801711698 1.1498097576611117 1.2525992516835889 0.8132880948386948 1.0 15.981220931549808 -5.954475852633091 6.5362839603818506 1.0783878866343355 0.8984038085658981 0.23567902300193988 0.15079700822815179 0.28502561674443644 29.647455825822764 0.040605198548434106 0.0602606933571245 1.1105142797292028e-06 5.954475852633091 -0.17998407806843741 T(ph)GSQEGTSMEGSR ddPTM_PC-9_Lapatinib_30min_R1 1 TGSQEGTSMEGSR 13 0 Q8IV36-3;Q8IV36-2;Q8IV36 Q8IV36-3 HID1 Protein HID1 1 T(0.699)GS(0.299)QEGTS(0.002)MEGSR 76.311 0.042499 2715100.0 6341.0 6811.4 5410.8 6276.3 6970.0 5710.6 10029.0 8059.2 7491.3 5557.0 True False 6250.57617720302 6795.628621791166 4965.944910292005 6737.88003912303 6560.038303547235 5466.3709500587875 10548.252547726119 8433.659853556079 6647.5509071137885 6517.520045762935 0.9590421100839641 1.0426709199320423 0.761937803861514 1.0338104051560764 1.0065236865380938 0.8387194687053546 1.6184457391248959 1.2939982990982641 1.0199509722160942 1.0 12.670107399688481 -7.221791886420532 24.999205710696135 1.257599084306305 0.9442297943898649 0.3878048852499578 0.17903837390876554 511.45303309470097 322490.34372533526 0.06756639466822387 0.05233591445299166 6.000785645514352e-08 7.221791886420532 -0.3133692899164401 T(ph)GSQEGTSMEGSRPAAPAEPGTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TGSQEGTSMEGSRPAAPAEPGTLK 24 1 Q8IV36-3;Q8IV36-2;Q8IV36 Q8IV36-3 HID1 Protein HID1 1 T(0.831)GS(0.165)QEGT(0.003)S(0.001)MEGSRPAAPAEPGTLK;T(0.498)GS(0.498)QEGT(0.003)S(0.001)MEGSRPAAPAEPGTLK 58.479 0.0051775 55949000.0 205486.8 219513.0 151506.3 226383.5 205866.0 197348.2 232783.8 160847.9 169032.2 200196.2 True False 240271.65669070138 241304.7999291224 155118.7847828421 213699.96644020957 165528.0351214463 186998.91298034933 210732.83325523438 156625.81305743748 171503.9761474951 236490.186307753 1.0159899674569473 1.0203586190891827 0.6559205995168889 0.9036314350994433 0.6999361694697929 0.7907258897288916 0.8910848967787625 0.6622930765237539 0.7252054676142499 1.0 17.851420791367673 -5.239866673871032 23.952827512294018 0.7833594358885101 1.0181744328300364 0.4177780869937405 0.10691404375909198 411.55806373362213 456961.99795188656 0.0255157606787685 0.06734454974952148 5.756166215000954e-06 5.239866673871032 0.2348149969415263 T(ph)GSQEGTSMEGSRPAAPAEPGTLK ddPTM_PC-9_Lapatinib_30min_R1 1 TGSQEGTSMEGSRPAAPAEPGTLK 24 1 Q8IV36-3;Q8IV36-2;Q8IV36 Q8IV36-3 HID1 Protein HID1 1 T(0.497)GS(0.497)QEGT(0.003)S(0.003)MEGS(0.001)RPAAPAEPGTLK 49.394 0.023381 24032000.0 32433.0 18657.0 25296.0 18170.0 23077.0 23202.0 20346.0 23451.0 20968.0 21202.0 True False 31970.499472516218 18613.80086278266 23216.260525383772 19506.28241334313 21719.656231127632 22209.70454650369 21399.416326257437 24540.619072084508 18606.36303717137 24866.737450110813 1.2856732627936178 0.7485421398817123 0.9336271222536399 0.7844327166954588 0.8734421342849238 0.8931491149999944 0.8605638905863815 0.9868853572495956 0.7482430324645767 1.0 14.601929615962097 -4.751058806838991 24.99500848045122 0.8693361536734282 1.2856741269546184 0.6832041146588972 0.08494024082494321 233.35853703095978 561858.1593360165 0.0192598196912064 0.2652903701501746 1.7739492581473966e-05 4.751058806838991 0.41633797328119015 T(ph)GSQGQCTQVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGSQGQCTQVR 11 0 P62857 P62857 RPS28 40S ribosomal protein S28 1 T(0.771)GS(0.229)QGQCTQVR 126.83 0.00095564 17977000.0 4012.8 4198.0 4409.9 5583.7 7565.9 7388.7 5662.7 8012.3 4435.9 4509.2 True False 4692.087783587295 4614.74969638453 4515.048740638882 5270.863391599644 6083.416207267593 7001.223564937032 5126.288061602287 7801.9856147335795 4500.766645601687 5326.682265192441 0.8808649643415103 0.8663459667080047 0.8476286956597294 0.9895208929660496 1.1420647796133965 1.3143685349297052 0.9623791708208984 1.4646988925388271 0.844947459136477 1.0 12.379021511853162 -6.050097729190628 2.863260527789072 1.1461235406696233 0.8660581649418869 0.3181639451072138 0.16638265454113943 0.2795288616185693 4.553571185084102 0.047720121557014085 0.06854568238029658 8.910504026975179e-07 6.050097729190628 -0.2800653757277364 T(ph)GSSGALGPPERR ddPTM_PC-9_AZD4547_30min_R2 1 TGSSGALGPPERR 13 1 Q9BZL4-3;K7EL81;Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-3;Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 T(0.975)GS(0.012)S(0.014)GALGPPERR 78.069 0.013083000000000001 5368200.0 16128.0 16705.0 26260.0 47799.0 36518.0 32439.0 24549.0 26872.0 24220.0 29933.0 True False 21256.36851676026 22104.564565920387 25911.77524202082 36779.67903718837 31448.10604656373 30410.58420194631 26733.813442285467 22719.549857129303 25500.219753890007 28885.0547808961 0.7358950390780884 0.7652595687836407 0.8970651237662968 1.2733117287183957 1.0887327818870116 1.052813797052556 0.9255240692832817 0.7865503468650329 0.8828170812663737 1.0 14.818035610320692 -5.396009297673492 4.078505198706526 1.0001613305462507 0.7523947701174049 0.38928569564456594 0.12371171544052771 0.2615373742703833 7.271354711870878 0.03783701367143476 0.0840860376933039 4.0178220912835854e-06 5.396009297673492 -0.24776656042884582 T(ph)GSSGALGPPERR ddPTM_PC-9_Lapatinib_30min_R1 2 TGSSGALGPPERR 13 1 Q9BZL4-3;K7EL81;Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-3;Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 T(0.904)GS(0.066)S(0.03)GALGPPERR;T(0.962)GS(0.019)S(0.019)GALGPPERR 72.523 0.01986 12700700.0 90494.0 39722.0 56482.0 45273.0 44852.0 47593.0 34788.0 30084.0 42670.0 36390.0 True False 89203.53896543266 39630.0261495124 51838.26798682508 48602.52744630072 42213.89354242481 45557.55833470176 36589.15242100872 31481.812467041516 37864.05526498011 42679.96301337293 2.090056613626457 0.9285393742514516 1.2145809022979372 1.1387668595465295 0.9890798998396019 1.0674226292189426 0.8572910995622051 0.7376251112770953 0.887162326104082 1.0 15.381271305467022 -3.156324875831109 1.6427706813227188 0.9694358850807723 199.99999999992667 0.8355284436851744 0.14522628241684873 102.1839931757246 2.010253894975676 0.04376232940807364 75288.87066664279 0.0006977102836742958 3.156324875831109 199.0305641148459 up T(ph)GSSSPPGGPPKPGSQLDSMLGSLQSDLNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TGSSSPPGGPPKPGSQLDSMLGSLQSDLNK 30 1 A0A1B0GTU4;F5GZ78;P49023;P49023-2;P49023-4;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 T(0.397)GS(0.187)S(0.174)S(0.174)PPGGPPKPGS(0.055)QLDS(0.013)MLGS(0.001)LQSDLNK;T(0.263)GS(0.263)S(0.236)S(0.236)PPGGPPKPGS(0.001)QLDSMLGSLQSDLNK 47.61600000000001 0.014573 112421000.0 67619.0 63085.3 62245.0 71983.0 81799.0 61566.8 77327.6 73744.6 71630.1 63937.1 True False 79065.56116387284 69347.99166777673 63729.156865477016 67950.0258820347 65771.07314903472 58338.12862584285 70002.56992465747 71808.88238886242 72677.55470166447 75528.39010419487 1.0468323375461637 0.9181711879745882 0.8437775090606291 0.8996620448058608 0.8708125919048522 0.7724000014479686 0.9268378397591385 0.9507535151987058 0.9622547839481612 1.0 16.204731415559856 -7.6781432096791775 3.4716889698836413 0.9694575849813155 0.8879965528593432 0.2180583254592129 0.06598918666933039 0.3880733246974071 9.177128039918484 0.03743123661489086 0.01931788545078466 2.098247867110731e-08 7.6781432096791775 -0.08146103212197231 T(ph)GSTSSKEDDYESDAATIVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGSTSSKEDDYESDAATIVQK 21 1 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 T(0.216)GS(0.152)T(0.211)S(0.211)S(0.211)KEDDYESDAATIVQK 68.309 0.0024541999999999997 32354000.0 19555.0 17264.0 17042.0 33804.0 27021.0 29074.0 42097.0 33988.0 32621.0 29869.0 True False 22865.27527114474 18977.85582619878 17448.345912144905 31910.071474046672 21726.429021871496 27549.308258148136 38109.26740411315 33095.85101326272 33098.02041213116 35284.01325712608 0.6480349926330105 0.5378598995500022 0.4945113750239559 0.9043776069776305 0.6157584417493538 0.7807872663856963 1.080071791335031 0.9379843152218115 0.9380457991253751 1.0 15.106727044097513 -6.709844336680891 0.8340062172715633 1.0002279943412076 0.5769615026834993 0.6648776244499789 0.11380718066530972 0.377744535801707 0.5765297164871835 0.07441002868094564 0.07439438144496534 1.950543603996426e-07 6.709844336680891 -0.42326649165770824 T(ph)GSYGALAEITASK ddPTM_PC-9_AZD4547_30min_R2 2 TGSYGALAEITASK 14 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 T(0.912)GS(0.088)YGALAEITASK;T(0.818)GS(0.182)YGALAEITASK 159.18 0.00037063 120818000.0 108926.0 121598.0 155484.0 186299.0 178098.0 175114.0 177988.0 172488.0 170125.0 155063.0 True False 143562.20219845147 160902.1755215078 153422.18056855907 143350.64384085775 153372.1668952549 164164.0938974575 193828.5871915561 145833.94297992412 179117.46018292903 149634.29156750411 0.9594204690285625 1.0753028188656906 1.025314311053801 0.9580066329661364 1.0249800716707007 1.097102089218624 1.2953487142625641 0.9746024220266011 1.197034839451385 1.0 17.191081308787957 -6.787041676835729 4.334196121863511 1.124542923736146 1.0094431945496645 0.2475307345091623 0.0908192976004443 0.2804555989557661 11.99062343436423 0.031018053489209805 0.028408700198873857 1.632895240464196e-07 6.787041676835729 -0.11509972918648148 T(ph)GSYGALAEITASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TGSYGALAEITASK 14 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 T(0.996)GS(0.004)YGALAEITASK;T(0.795)GS(0.205)YGALAEITASK;T(0.997)GS(0.003)YGALAEITASK;T(0.661)GS(0.339)YGALAEITASK 222.75 6.5844e-17 201827700.0 199607.0 217562.0 176781.0 243629.0 278870.0 183642.0 235515.0 188962.0 168908.0 173722.0 True False 233396.52268204503 239160.1175428324 180996.12948567563 229979.25698587467 224227.42538504562 174011.4902367354 213205.31421905826 184001.94772178875 171377.95995745854 205216.42341740508 1.1373189279657328 1.1654043743681601 0.8819768246205812 1.1206669191290923 1.0926387939671507 0.8479413457216355 1.0389291006470958 0.8966238893440481 0.8351084045982033 1.0 17.646786668513883 -5.01480771854523 0.391796999626935 0.9124540102582791 1.286407202524927 0.3454542344993685 0.09768051894976 5.650567201092356 0.7877440303394058 0.08609681956231896 0.9799199785610084 9.664786873155112e-06 5.01480771854523 0.3739531922666478 T(ph)GSYGALAEITASK ddPTM_PC-9_Lapatinib_30min_R1 2 TGSYGALAEITASK 14 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 T(0.884)GS(0.116)YGALAEITASK;T(0.869)GS(0.131)YGALAEITASK 187.08 1.1289000000000002e-05 78127200.0 196891.7 149325.4 157483.0 165645.3 159746.8 168986.4 156908.4 144325.0 177560.8 126568.2 True False 194083.9882524848 148979.64621082545 144535.35564195964 177827.4079385225 150350.80729829267 161759.24559853828 165032.34919330222 151030.86638431597 157562.0329058841 148445.34472847474 1.307444087300204 1.0035993145041229 0.9736604129037056 1.1979318601320321 1.0128361220980238 1.089688908024811 1.111738124864523 1.017417330671908 1.0614144431008257 1.0 17.17957232530633 -4.754002415693607 24.998377740086884 1.0565041318666228 1.307444531016127 0.5912355813109522 0.06361395062537403 189.2096663462373 635950.4557025768 0.015531942648313164 0.1578671968087478 1.7619662457288866e-05 4.754002415693607 0.25094039914950406 T(ph)GTPSDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGTPSDPR 8 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 T(0.393)GT(0.393)PS(0.215)DPR 106.68 0.009345399999999998 22082000.0 239810.0 337750.0 269130.0 387770.0 449140.0 290100.0 378700.0 313950.0 265880.0 305910.0 True False 280405.0965365998 371279.58788801223 275547.07988120825 366044.5040673021 361134.24117846735 274886.64530813723 342826.79444943 305709.1451575209 269767.9920044589 361369.06141777243 0.7759521399991361 1.0274249445466015 0.762508773717773 1.012938137623587 0.9993501927409507 0.7606811834684032 0.9486888365716897 0.8459748711140933 0.7465165693655906 1.0 18.463113469710144 -6.752945250577164 24.99997111210359 0.856265500155032 0.9187441096185827 0.05772178551721585 0.11066580231196342 549.5785131043177 1617521.174463547 0.035302699489494244 0.03476682504219059 1.7662604706397528e-07 6.752945250577164 0.06247860946355066 T(ph)GTPSDPR ddPTM_PC-9_Lapatinib_30min_R1 1 TGTPSDPR 8 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 T(0.717)GT(0.181)PS(0.102)DPR 120.87 0.0083061 17747000.0 331200.0 352030.0 172150.0 253120.0 210140.0 153270.0 175700.0 152080.0 174580.0 134810.0 True False 326477.02726535936 351214.8961636589 157996.491518217 271735.2891835669 197779.97835113606 146714.99938982082 184796.88629329723 159146.19199533548 154916.96199109967 158111.7288769665 2.0648501511194346 2.2213083030478673 0.9992711650200273 1.7186282833895 1.2508874563318269 0.9279197718721174 1.168774053676281 1.0065426083549687 0.9797942448130916 1.0 17.270584866579675 -4.429681768283383 0.49604017180969606 0.9872978152351697 3.5584974399591576 0.6971672794548665 0.2536645945059425 3.382549502854817 0.4946369703291894 0.15213732942041402 5.454969287928128 3.718075733881345e-05 4.429681768283383 2.571199624723988 T(ph)GVPSTASVGK ddPTM_PC-9_AZD4547_30min_R2 1 TGVPSTASVGK 11 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7;H7BZ26 E9PHV5 SSFA2 Sperm-specific antigen 2 1 T(0.971)GVPS(0.023)T(0.005)AS(0.001)VGK 78.334 0.045248000000000003 4055100.0 29331.0 33778.0 31729.0 44026.0 38816.0 43077.0 25536.0 36661.0 32330.0 34576.0 True False 38657.64787730006 44696.07793520852 31308.25272863968 33876.485894919446 33427.0684129311 40383.38838025957 27808.654530213083 30995.884835971177 34038.89779699685 33365.50476411534 1.1586112109077524 1.3395894427852093 0.9383419477685156 1.0153146530950632 1.0018451286516117 1.2103335065888758 0.8334552324867369 0.9289799466575822 1.0201823121706746 1.0 15.026069709121273 -5.266199299844199 24.99815708668134 0.9941173765269838 1.2491003325680592 0.5172440680914494 0.09874975078349317 284.2519633429418 1492841.48460173 0.02596993759349885 0.0569984601154682 5.417522206264052e-06 5.266199299844199 0.25498295604107535 T(ph)HLTRHMRT(ph)HS(ph)GEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 THLTRHMRTHSGEK 14 2 Q13127 Q13127 REST RE1-silencing transcription factor 3 T(0.984)HLT(0.017)RHMRT(0.999)HS(0.999)GEK 51.211000000000006 0.039564999999999996 3128800.0 16206.0 13764.0 19832.0 19185.0 17685.0 15827.0 16535.0 18176.0 20096.0 17023.0 True False 18949.35571690982 15130.39895689297 20304.87009327884 18110.1266486092 14219.751202834748 14997.004258158866 14968.685096966788 17698.89925906388 20389.86598210319 20109.135146006152 0.9423257429682811 0.7524142061324799 1.0097336332891256 0.9005920203488227 0.7071289291950934 0.7457806687990458 0.7443723953458883 0.8801422403578124 1.0139603634894658 1.0 14.295563415076423 -8.152128774677282 3.85090250894774 1.0072866634346418 0.8270399242894787 0.3624673662272795 0.09276699586407855 0.27126143770371436 6.840538829107686 0.07666568292690308 0.025736216512106686 7.0448414812242586e-09 8.152128774677282 -0.1802467391451631 T(ph)HPYSPK ddPTM_PC-9_AZD4547_30min_R2 1 THPYSPK 7 0 E9PME6;B1AQP1;P22415;M0QZ39;M0R1C6;H0YD59;M0QXT0;B4DLJ1;Q15853-4;P22415-2;Q15853-3;Q15853-2;Q15853 E9PME6 USF1;USF2 Upstream stimulatory factor 1;Upstream stimulatory factor 2 1 T(0.986)HPY(0.006)S(0.008)PK 88.64299999999999 0.035929 3956900.0 91765.0 89920.0 80494.0 120410.0 99326.0 101650.0 94435.0 94183.0 84316.0 102480.0 True False 120944.36116942635 118984.88151856107 79426.59696615467 92651.33481595531 85536.29939155997 95293.80943086556 102839.53205516405 79629.18146003316 88772.77162547444 98892.2063924843 1.2229918370859405 1.2031775390502744 0.8031633620441804 0.9368921798371032 0.8649447970862609 0.9636129368239861 1.0399154372895025 0.8052119005617099 0.8976720700633603 1.0 16.593569207490773 -5.246219946004421 23.896302981179563 0.9123148378429892 1.2130848340028617 0.7289155233924032 0.07296976639917223 222.80863877200187 349832.80580725084 0.018519416815028205 0.048524434395128074 5.6725724839778554e-06 5.246219946004421 0.30076999615987254 T(ph)HPYSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 THPYSPK 7 0 E9PME6;B1AQP1;P22415;M0QZ39;M0R1C6;H0YD59;M0QXT0;B4DLJ1;Q15853-4;P22415-2;Q15853-3;Q15853-2;Q15853 E9PME6 USF1;USF2 Upstream stimulatory factor 1;Upstream stimulatory factor 2 1 T(1)HPYSPK 99.13600000000001 0.025036000000000003 12521000.0 152390.0 149110.0 127240.0 184410.0 176360.0 173700.0 158780.0 150220.0 144670.0 135540.0 True False 178186.61716030445 163912.6553663405 130273.88416038746 174078.10556528645 141803.52401085297 164590.8662186262 143739.2089323484 146276.88417124646 146785.52506124967 160112.32906595044 1.1128850488890782 1.0237353757987289 0.8136405542306958 1.0872248663223398 0.885650248410564 1.027971219822997 0.8977397916255535 0.9135891347317473 0.9167659100180134 1.0 17.2887248778404 -5.007300958912917 10.565574621076756 0.9425688041954513 1.0909045707001457 0.3412325142889553 0.0744165771481825 0.1999686512548816 289.147225351831 0.017435509548437252 0.05561266405965234 9.833294385140011e-06 5.007300958912917 0.14833576650469438 T(ph)HSAGTSPTITHQK ddPTM_PC-9_AZD4547_30min_R2 1 THSAGTSPTITHQK 14 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 T(0.56)HS(0.088)AGT(0.176)S(0.176)PT(0.001)ITHQK 75.445 0.036642 12179000.0 12445.0 14086.0 16213.0 27797.0 25990.0 21996.0 18429.0 24112.0 17386.0 24812.0 True False 16402.25112791925 18639.02403325678 15998.005026613993 21388.831109368923 22381.737120055648 20620.586642806833 20069.14529829642 20386.044438638804 18304.988465777533 23943.339432185014 0.6850444222442542 0.7784638431931475 0.6681609752860632 0.8933102740304354 0.9347792601549041 0.8612243376163442 0.8381932418048235 0.8514286194863679 0.7645127580312243 1.0 14.547336761833519 -5.767675384459759 24.999870440726056 0.8714988033157232 0.7173471491820141 0.5852780016620578 0.06422957526234373 106.83754963737783 428308.7738711098 0.017751462587182614 0.02708428063485172 1.7073580853546184e-06 5.767675384459759 -0.15415165413370902 T(ph)HSEGSLLQEPR ddPTM_PC-9_AZD4547_30min_R2 2 THSEGSLLQEPR 12 0 P49796-1;P49796-4;P49796-6;P49796;C9J582 P49796-1 RGS3 Regulator of G-protein signaling 3 1 T(0.942)HS(0.058)EGSLLQEPR;T(0.957)HS(0.043)EGSLLQEPR 153.81 0.00016612 17719600.0 9417.6 11430.9 17196.199999999997 24543.7 26230.0 19319.5 13804.5 22978.8 14205.5 18323.0 True False 12412.200901751092 15125.714881567153 16968.167152202524 18885.52916138498 22588.41726275719 18111.448610915908 15033.073757139997 19427.95446029336 14956.373728896966 17681.51734708715 0.7019873157999009 0.8554534424082649 0.959655600767649 1.0680943716912497 1.2775157708101563 1.0243152923693841 0.8502140094677193 1.098771902825066 0.8458761448638273 1.0 14.109954465092555 -5.038713370254731 1.8158972172259054 1.0290282218926756 0.6797756055277355 0.42928348431698615 0.11688915514173404 0.5193001044608642 2.5454415608619176 0.03445773001721991 0.2624185487904052 9.147167456317788e-06 5.038713370254731 -0.3492526163649401 T(ph)HSEGSLLQEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 THSEGSLLQEPR 12 0 P49796-1;P49796-4;P49796-6;P49796;C9J582 P49796-1 RGS3 Regulator of G-protein signaling 3 1 T(0.806)HS(0.194)EGSLLQEPR;T(0.613)HS(0.387)EGSLLQEPR 135.94 0.00014476 11498000.0 6429.700000000001 9865.1 20013.6 19375.2 21146.4 15269.8 19237.5 20247.6 13979.9 13767.2 True False 7518.121217636378 10844.441931825397 20490.800126000657 18289.670359245927 17002.914720702553 14469.024807053398 17415.184732561145 19716.121954105532 14184.329590127607 16263.084378904765 0.462281387864427 0.666813359579686 1.259957806809375 1.1246126462314796 1.0454913917041124 0.8896851587280403 1.0708414423005022 1.2123236585847015 0.8721795484580059 1.0 13.989313277562502 -5.081025815139345 4.594300720844339 1.0618509770396247 0.501489964870507 0.7458128840986615 0.11805227819627684 0.09551276366776981 3.547554255889097 0.0308060361686546 0.09389376131073023 8.298014413603856e-06 5.081025815139345 -0.5603610121691177 T(ph)HSEGSLLQEPR ddPTM_PC-9_Lapatinib_30min_R1 1 THSEGSLLQEPR 12 0 P49796-1;P49796-4;P49796-6;P49796;C9J582 P49796-1 RGS3 Regulator of G-protein signaling 3 1 T(0.95)HS(0.047)EGS(0.003)LLQEPR 105.95 0.0042287 5136300.0 4258.0 7680.7 10975.0 5657.6 9341.5 9408.9 7778.1 9805.3 11155.0 6803.9 True False 4197.280139178435 7662.9158110508015 10072.67786472514 6073.67877720034 8792.05133609563 9006.503280217154 8180.811959464409 10260.890034007514 9898.606432642438 7979.945049373129 0.5259785766956071 0.9602717517024466 1.2622490258271148 0.7611178698125826 1.1017684058847368 1.1286422681475314 1.0251714653231927 1.2858346731113852 1.2404354129506232 1.0 12.962163096614741 -4.801168234094479 3.3506429450102346 1.0981986937225874 0.46304831900181276 0.58231790494811 0.14604691433118372 0.2120249443173265 3.843137210292525 0.03763191521837655 0.3403095060279167 1.5806356245949147e-05 4.801168234094479 -0.6351503747207746 T(ph)HSFENVSCHLPDSR ddPTM_PC-9_AZD4547_30min_R2 1 THSFENVSCHLPDSR 15 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 T(0.59)HS(0.41)FENVSCHLPDSR 160.76 0.00060776 15558000.0 34222.0 29422.0 48116.0 89688.0 58896.0 49557.0 39608.0 62836.0 46500.0 45918.0 True False 45103.88413818019 38932.086121431275 47477.95040156409 69011.81726578687 50719.30701896103 46458.1929558819 43133.035269136926 53126.140027633905 48957.8950683685 44310.42479635146 1.017906832206539 0.8786213695842736 1.0714848846466813 1.557462325919054 1.144635991463961 1.048470944916495 0.9734286111535658 1.1989535255371404 1.1048843538146291 1.0 15.43535853730655 -5.517469724875173 24.98953673403712 1.1568439607788321 0.9549613084412917 0.20051794830587766 0.15649056824859844 354.2775324737285 1636751.036997994 0.04450585132384453 0.08015777144218424 3.037597838703673e-06 5.517469724875173 -0.20188265233754044 T(ph)HSTSSSLGSGESPFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 THSTSSSLGSGESPFSR 17 0 F8WBF9;Q5TH30;Q9UGV2-3;Q9UGV2-2;Q9UGV2 F8WBF9 NDRG3 Protein NDRG3 1 T(0.477)HS(0.477)T(0.046)SSSLGSGESPFSR 166.21 5.0987e-05 10985000.0 3631.1 4123.7 13156.0 19410.0 31054.0 38293.0 32650.0 31350.0 35204.0 17488.0 True False 4245.77351250594 4533.073683416124 13469.688934407846 18322.520628069044 24969.19162300423 36284.84766902617 29557.155634470244 30527.09571807068 35718.79190057526 20658.435965068184 0.2055225051734417 0.21942966500858058 0.6520188148407773 0.8869268060297986 1.2086680552789766 1.7564179461785507 1.4307547620956933 1.4777060455926885 1.729017238331739 1.0 14.334443412510703 -5.86919946024434 1.153451555141345 1.5092343942999273 0.1665697998910035 0.8488603221566233 0.20947292865620437 0.17474479069461848 0.4646279296726277 0.07557598922676413 0.17695397371945484 1.3514517337457844e-06 5.86919946024434 -1.342664594408924 T(ph)HTGERPNACADCGK ddPTM_PC-9_Lapatinib_30min_R1 1 THTGERPNACADCGK 15 1 Q6DD87 Q6DD87 ZNF787 Zinc finger protein 787 1 T(0.5)HT(0.5)GERPNACADCGK 69.229 0.016332 2818900.0 18642.0 20672.0 22051.0 18887.0 20545.0 17742.0 13717.0 14245.0 16758.0 15566.0 True False 18376.161661475886 20624.135254083885 20238.051899321556 20276.01298518501 19336.583493024114 16983.216018622035 14427.19914220353 14906.874703929208 14870.537570436762 18256.562359608768 1.006551030775198 1.129683389886871 1.1085357418709165 1.1106150536885366 1.0591579680852081 0.9302526775903928 0.7902473016564494 0.8165214463873832 0.8145310862759506 1.0 14.156127516523297 -6.85762377778571 2.6864151467320565 0.8407013429320643 1.0923321204476968 0.747793956911621 0.06269050562407484 0.12101972607701585 1.7730175473177605 0.02313662432699215 0.020273179765176924 1.3879576732839377e-07 6.85762377778571 0.25163077751563245 T(ph)HVGSYK ddPTM_PC-9_Lapatinib_30min_R1 1 THVGSYK 7 0 H0Y8R1;F5H5I6;H0YAK1;Q12849-5;Q12849 H0Y8R1 GRSF1 G-rich sequence factor 1 1 T(0.949)HVGS(0.051)YK 87.639 0.037342 1105100.0 28644.0 25448.0 21489.0 30607.0 19604.0 11078.0 13203.0 14376.0 21046.0 24258.0 True False 28235.531307333735 25389.076719520464 19722.25736993882 32857.94088195892 18450.931262946924 10604.219764079293 13886.586737224841 15043.961442168225 18675.577855794967 28450.962978246767 0.9924279655814199 0.8923802241397811 0.6932017515547083 1.1548973195417558 0.6485169334006116 0.372719186067169 0.4880884611126289 0.5287680931457625 0.6564128556939907 1.0 14.796189863730843 -6.500999130885367 22.86555200123891 0.5653365873102768 0.9117325323135232 0.3946690210099728 0.18852168063430855 236.92179268240807 247598.05264625532 0.05635677882520168 0.06321869210047987 3.1550109372090046e-07 6.500999130885367 0.34639594500324644 T(ph)IETSPSLSR ddPTM_PC-9_Lapatinib_30min_R1 1 TIETSPSLSR 10 0 H3BP78;F8W7R3;Q9NVI1-2;Q9NVI1-1;Q9NVI1 H3BP78 FANCI Fanconi anemia group I protein 1 T(0.344)IET(0.327)S(0.327)PS(0.002)LSR 150.15 0.00038995 41641000.0 95786.0 80621.0 107000.0 75637.0 83377.0 83597.0 68488.0 74493.0 87356.0 53991.0 True False 94420.0740749987 80434.32702783939 98202.87303194459 81199.59729763556 78472.92878548898 80021.751184125 72033.97352564223 77954.21673006662 77517.047380539 63323.27241151462 1.4910801428801315 1.270217472418771 1.5508180372258764 1.2823026070091463 1.2392431060025189 1.2637020819785356 1.1375592382137165 1.2310516143807426 1.2241478437308841 1.0 15.95044819235041 -1.5228787467695548 0.08656031369916492 0.7998617723762632 2.6133888252683417 0.6725567808335948 0.08543678565919549 100.59764656669006 0.6316101901196669 1.8188655417074762 21.696342150269512 0.029999999897128517 1.5228787467695548 1.8135270528920784 T(ph)IHTFPCLK ddPTM_PC-9_AZD4547_30min_R2 2 TIHTFPCLK 9 0 Q86X02 Q86X02 CDR2L Cerebellar degeneration-related protein 2-like 1 T(0.996)IHT(0.004)FPCLK;T(1)IHTFPCLK 103.31 0.0060739 7537000.0 56294.0 55348.0 83774.0 101307.0 83999.0 74406.0 72771.0 94624.0 75163.0 89494.0 True False 74194.32101206 73238.15861086865 82663.10202304077 77952.2363275474 72337.18877828206 69753.38105767801 79247.47802389335 80002.03504320481 79135.96273169428 86360.84229985367 0.8591199325551936 0.848048220240584 0.9571826747129913 0.9026340439905539 0.837615600449101 0.8076968589014816 0.9176320646426537 0.9263693233263007 0.9163407931678819 1.0 16.398089693960074 -8.486821313593007 0.9368760559804427 0.996686641625084 0.8743906565563612 0.46012645562192855 0.041079007786405046 0.5915499426914226 1.1502484090145189 0.0428026880896818 0.014716056277203803 3.259707910515219e-09 8.486821313593007 -0.12229598506872286 T(ph)ILETSFHQHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TILETSFHQHR 11 0 Q5M775;Q5M775-4;Q5M775-2;Q5M775-5;Q5M775-3 Q5M775 SPECC1 Cytospin-B 1 T(0.996)ILET(0.003)S(0.001)FHQHR 78.548 0.033749 0.0 8287.4 10301.0 9088.2 9583.5 11501.0 8821.0 9647.9 8951.4 6661.8 7915.2 True False 9690.293136388893 11323.615203062662 9304.897155190438 9046.567565126212 9247.461610619306 8358.411231516986 8733.981067252847 8716.435234792276 6759.216222112607 9350.163103311272 1.0363769090784274 1.2110607139090985 0.9951588065768817 0.9675304553695385 0.9890160747403867 0.8939321313611025 0.9340993275464672 0.9322228006595342 0.7228982155101545 1.0 13.190775816110058 -5.827887762051009 0.7895657731729101 0.8885785582173013 1.1409791393113102 0.4800520217112718 0.08345388737763626 0.7118262513780909 0.8140718082572052 0.03910203058049238 0.12331591754433958 1.4863197132999188e-06 5.827887762051009 0.252400581094009 T(ph)ILYDMY(ph)S(ph)YVWDIKS(ph)IMS(ph)MVK ddPTM_PC-9_AZD4547_30min_R2 1 TILYDMYSYVWDIKSIMSMVK 21 1 O60502-3;O60502-2;O60502-4;O60502 O60502-3 MGEA5 Protein O-GlcNAcase 5 T(0.544)ILY(0.505)DMY(0.904)S(0.55)Y(0.511)VWDIKS(0.993)IMS(0.993)MVK 48.477 0.045708 0.0 520.24 1215.4 1058.8 4133.0 2374.4 2261.7 523.33 1485.6 765.07 1378.8 True False 685.6654983357736 1608.2542815575955 1044.7596201923695 3180.200704213468 2044.7555451273606 2120.27554146373 569.9053561754553 1256.0346556918466 805.5100382786386 1330.5286316740578 0.5153331405375893 1.2087333134155152 0.7852214490701064 2.3901783310083085 1.5367993566246445 1.5935587487478722 0.42833002057115155 0.9440117452500939 0.6054060161525077 1.0 10.377783840741673 -7.2568470061881625 24.982447076249972 0.7397712551030372 1.3641093426915503 0.2566725040913468 0.4939072200256671 564.9983359578108 3073593.4233484142 0.2023143664018923 0.1513794526826612 5.535450784352048e-08 7.2568470061881625 0.6243380875885131 T(ph)IS(ph)FRSRVLPS(ph)NAVWMENSKLK ddPTM_PC-9_Lapatinib_30min_R1 1 TISFRSRVLPSNAVWMENSKLK 22 3 H7C5Q2;Q9Y305-3;Q9Y305-2;Q9Y305;Q9Y305-4 H7C5Q2 ACOT9 Acyl-coenzyme A thioesterase 9, mitochondrial 3 T(0.989)IS(0.928)FRS(0.481)RVLPS(0.602)NAVWMENSKLK 69.148 0.007448699999999999 0.0 9569.9 13723.0 11008.0 11921.0 11230.0 10480.0 9269.2 9646.2 14709.0 9387.9 True False 9433.43147109528 13691.225236638598 10102.96473210882 12797.71010729023 10569.47347902948 10031.794830073204 9749.11382145607 10094.397667184408 13052.317527363297 11010.586006409556 0.856760163864469 1.2434601781111896 0.9175683043779518 1.162309626375957 0.9599374159446834 0.9111045337853434 0.8854309675961708 0.9167902290857354 1.1854335018831146 1.0 13.426603633741728 T(ph)ISAQDTLAYATALLNEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TISAQDTLAYATALLNEK 18 0 Q9UPU5;A0A0U1RQI9 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 T(0.542)IS(0.413)AQDT(0.039)LAY(0.004)AT(0.002)ALLNEK 95.365 0.0022023000000000004 1772300.0 2915.0 1203.0 2620.9 3498.2 4308.2 4000.9 4730.5 3607.8 3452.0 3309.5 True False 3408.451926125641 1322.4258896499728 2683.392195818601 3302.207195317421 3464.039136672469 3791.0857608180845 4282.392794145837 3513.0990727800763 3502.478969457613 3909.4861520124136 0.8718414117853149 0.3382607939330472 0.6863797674375496 0.8446652749025866 0.8860599582605887 0.969714589951065 1.0953850781493288 0.8986089056669772 0.8958924097108534 1.0 11.932763282307283 -5.867716630401961 2.0385449039841648 0.9608442425895882 0.5888946821798118 0.5447687937736606 0.13357713088097276 0.2241390459602784 1.8986626712852 0.04043276081863536 0.07168466002584377 1.3560739384164627e-06 5.867716630401961 -0.37194956040977645 T(ph)ISAQDTLAYATALLNEK ddPTM_PC-9_Lapatinib_30min_R1 1 TISAQDTLAYATALLNEK 18 0 Q9UPU5;A0A0U1RQI9 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 T(0.955)IS(0.045)AQDTLAYATALLNEK 147.84 0.00010159 709760.0 6766.3 8658.8 8871.9 9488.1 12873.0 11328.0 11723.0 10420.0 12911.0 9738.8 True False 6669.8113212125445 8638.751080595082 8142.486628524368 10185.886525373748 12115.83544929176 10843.527846857753 12329.95957892046 10904.1512400802 11456.827221142677 11422.138603864692 0.5839371725848088 0.7563164290155043 0.7128688340175936 0.8917670218016215 1.060732658697764 0.9493430453723293 1.0794790718743865 0.9546505797426386 1.0030369634339973 1.0 13.47954517598853 -5.848976472423618 2.205653715277091 1.0072446027106716 0.6759340113582992 0.874521436802691 0.054843393160417614 0.09548026100431825 0.946971901785587 0.016000049065851743 0.028154815847020655 1.4158704815961327e-06 5.848976472423618 -0.3313105913523724 T(ph)ISDGTISASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TISDGTISASK 11 0 A0A075B6Q2;S4R347;Q5T0N5-3;Q5T0N5-4;Q5T0N5-2;Q5T0N5-5;Q5T0N5 A0A075B6Q2 FNBP1L Formin-binding protein 1-like 1 T(0.518)IS(0.356)DGT(0.124)IS(0.001)ASK 100.04 0.010546999999999999 25457000.0 19717.0 21826.0 22493.0 29867.0 37056.0 29358.0 34318.0 29312.0 31970.0 22164.0 True False 23054.698671498893 23992.741036991123 23029.318425177527 28193.64882012048 29795.142808721735 27818.414798194735 31067.150599196037 28542.591058631195 32437.500768702153 26182.15774987255 0.8805499871992453 0.9163775295452078 0.8795806153635153 1.0768267875193642 1.13799416737785 1.0624951183914608 1.1865771681612935 1.0901542696101942 1.2389162527622481 1.0 14.676296378542393 -5.837907975842808 4.075083164594866 1.1230737982492651 0.8933937500571832 0.7269510228818425 0.06239752110119739 0.10326176539462018 3.290431831364548 0.016781335892892633 0.026397451780623533 1.4524193431332379e-06 5.837907975842808 -0.22968004819208188 T(ph)ISDGTISASK ddPTM_PC-9_Lapatinib_30min_R1 1 TISDGTISASK 11 0 A0A075B6Q2;S4R347;Q5T0N5-3;Q5T0N5-4;Q5T0N5-2;Q5T0N5-5;Q5T0N5 A0A075B6Q2 FNBP1L Formin-binding protein 1-like 1 T(0.569)IS(0.431)DGTISASK 151.26 0.00087468 22897000.0 59065.0 59597.0 70282.0 63500.0 66941.0 73678.0 65127.0 64437.0 73535.0 66457.0 True False 58222.72226880556 59459.00680812875 64503.685256365534 68170.00182979032 63003.66199106968 70526.96369180667 68498.95739114165 67430.9782588337 65252.71394212122 77944.0039016137 0.7469814142765657 0.7628426027893308 0.8275644312266346 0.8746022582550314 0.8083195478461339 0.9048414266840932 0.8788226670727073 0.8651207903554676 0.8371742619802762 1.0 16.250150422688883 -1.5228787452805947 0.06044119105217975 1.1823987282743222 0.15122310550172158 0.7292974979842065 0.03596510278857786 190.30375226382174 0.8622317244944446 2.9655719322216583 17.258138498659754 0.029999999999982235 1.5228787452805947 -1.0311756227726008 T(ph)ISDGTISASKQESGK ddPTM_PC-9_Lapatinib_30min_R1 1 TISDGTISASKQESGK 16 1 A0A075B6Q2;S4R347;Q5T0N5-3;Q5T0N5-4;Q5T0N5-2;Q5T0N5-5;Q5T0N5 A0A075B6Q2 FNBP1L Formin-binding protein 1-like 1 T(0.486)IS(0.455)DGT(0.013)IS(0.045)AS(0.001)KQESGK 66.893 0.018688999999999997 7910600.0 116600.0 11437.0 26159.0 19824.0 12122.0 15912.0 7099.8 6227.9 26409.0 8025.2 True False 114937.26261817888 11410.51832918719 24008.307996660118 21281.923090925397 11409.007792768953 15231.480852683673 7467.392904411795 6517.270970066741 23434.540320901313 9412.345127093167 12.211331083401866 1.212292810677154 2.5507254220367344 2.2610648890961285 1.2121323260797618 1.6182450438244438 0.7933615696811963 0.6924173393628504 2.489766365817341 1.0 13.200338506203586 -4.760336534534695 24.99999487703303 1.5505607579335827 12.211343746898606 0.9603534501285734 0.6506672005799536 4.955872974847105 112292.25945827978 0.16762445597895995 1.0004379199708329 1.736454729537971e-05 4.760336534534695 10.660782988965023 T(ph)ISEPDEQR ddPTM_PC-9_AZD4547_30min_R2 1 TISEPDEQR 9 0 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 T(0.625)IS(0.375)EPDEQR 145.46 0.0012032 14458000.0 75490.0 82463.0 101170.0 83367.0 95390.0 114030.0 91804.0 132380.0 99930.0 84347.0 True False 99494.24971045594 109117.55209814369 99828.41969669622 64148.026157310385 82146.7450512547 106899.68607379787 99974.37815208637 111923.71278977273 105212.09578886168 81394.03720322855 1.222377622847653 1.3406086716855403 1.2264832059803081 0.7881170213629102 1.0092477025822757 1.313360164294168 1.2282764387576148 1.375084915745317 1.2926265781136161 1.0 16.312635488384622 -6.776338261169602 24.99364382289917 1.2644628631187371 1.1175395152424017 0.11465189925778285 0.1671937186695696 511.28680525427586 857704.5135125163 0.06377970300605516 0.05647641726012407 1.6736388125989245e-07 6.776338261169602 -0.14692334787633543 T(ph)ISEPDEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TISEPDEQR 9 0 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 T(0.999)IS(0.001)EPDEQR 108.47 0.00595 13239000.0 137400.0 196750.0 186050.0 173210.0 186930.0 132080.0 166600.0 129340.0 111910.0 107870.0 True False 160659.10622629954 216282.0397245489 190486.13759855434 163505.60525439706 150302.40838823252 125153.49228644859 150818.44192045153 125944.96204705784 113546.47203708052 127425.97710155013 1.2608034082270743 1.6973151365532502 1.4948768055884665 1.2831418598744104 1.1795272189158996 0.9821662359058033 1.1835768918629452 0.9883774479256139 0.8910778996545692 1.0 16.959299890298553 -6.190031039937811 1.46256092601724 1.0149991310265143 1.5104440473234957 0.7335128997176313 0.12358021364045696 0.20291426789798117 0.869735392979143 0.0451908322385881 0.06649097700630267 6.456080844213113e-07 6.190031039937811 0.4954449162969814 T(ph)ISEPDEQRSELPR ddPTM_PC-9_AZD4547_30min_R2 1 TISEPDEQRSELPR 14 1 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 T(0.996)IS(0.004)EPDEQRSELPR 93.90899999999999 0.0025783 19559000.0 10395.0 12374.0 26618.0 41205.0 38596.0 22059.0 13716.0 37256.0 17400.0 19169.0 True False 13700.393770568138 16373.653513241474 26265.027928107756 31705.823860903944 33237.61161545468 20679.64724284759 14936.697428587198 31498.94125771101 18319.728477195953 18497.8991445895 0.7406459330045273 0.8851628709431388 1.4198924819951828 1.7140229608278335 1.7968317026518354 1.1179457235226755 0.8074807475072688 1.7028388473468468 0.9903680593130674 1.0 14.175073808897029 -5.175947950271654 4.472514898401864 1.3493086934386787 0.7802108232901834 0.276528530364493 0.3264949178682443 0.28236190681812434 9.985869195667435 0.08756822087878406 0.25318679375073616 6.668866900796041e-06 5.175947950271654 -0.5690978701484952 T(ph)ISGIPR ddPTM_PC-9_Lapatinib_30min_R1 2 TISGIPR 7 0 A0A087WU78;A0A087WWC4;Q6T4R5-4;Q6T4R5-3;Q6T4R5-2;Q6T4R5 A0A087WU78 NHS Nance-Horan syndrome protein 1 T(0.998)IS(0.002)GIPR;T(0.998)IS(0.002)GIPR 96.03399999999999 0.031627999999999996 14477500.0 26927.0 32619.0 30583.5 26425.9 29932.0 32589.0 24150.0 24276.4 31023.0 21522.1 True False 26543.01604219298 32543.472709605398 28069.042685724013 28369.348840218172 28171.458608576188 31195.244438669455 25400.368833142464 25404.370169355378 27528.863053327324 25242.16630860437 1.0515347897515905 1.2892503880901938 1.1119902445201797 1.1238872485578955 1.1160475794414404 1.2358386383040287 1.006267390944341 1.006425908884679 1.0905903525381448 1.0 14.62354810875135 -7.278921678662309 24.93134357835655 1.0263563938323448 1.155764643717425 0.4686721644979045 0.0672498493539085 712.6064678724584 1016237.6159762086 0.027067417237385726 0.018299102882490696 5.2611213771139264e-08 7.278921678662309 0.12940824988508015 T(ph)ISNPEVVMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TISNPEVVMK 10 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6;F8W9I4;E9PFY5 A8MQ02 MLLT4 Afadin 1 T(0.718)IS(0.282)NPEVVMK 86.262 0.043465 31902000.0 105070.0 91726.0 101390.0 112540.0 130930.0 109430.0 114630.0 113130.0 101290.0 63809.0 True False 122856.27577290633 100831.9510839847 103807.52212371615 106234.7486596026 105275.20638886934 103691.2981594949 103771.41655066861 110160.45737114322 102771.17462814652 75377.0665882339 1.6298893195730142 1.3377006515098882 1.377176465234323 1.4093775927887526 1.3966476960951733 1.3756345643686902 1.3766974657895081 1.4614585358292371 1.3634276216871082 1.0 16.201838030999657 -8.58927520103445 13.130134477902415 0.9999999979975559 1.412247127795258 0.7251074226115239 0.07709270415764645 30.009906194828318 5935.152615903117 0.07072640614255642 0.0182623751900587 2.574689126928241e-09 8.58927520103445 0.41224712979770206 T(ph)ISNPEVVMK ddPTM_PC-9_Lapatinib_30min_R1 4 TISNPEVVMK 10 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6;F8W9I4;E9PFY5 A8MQ02 MLLT4 Afadin 1 T(0.932)IS(0.068)NPEVVMK;T(0.815)IS(0.185)NPEVVMK;T(0.932)IS(0.068)NPEVVMK;T(0.953)IS(0.047)NPEVVMK 137.62 0.00026999 31884100.0 203279.0 195385.0 196709.0 176226.0 184061.0 164697.0 158417.0 148437.0 183527.0 145436.0 True False 200380.20418319717 194932.5980369186 180536.34533869827 189186.2479127025 173234.89385784915 157653.29323745877 166619.0571196658 155333.92491591015 162856.25663501295 170574.41881871095 1.1747377219333472 1.1428008923430417 1.0584022304691245 1.1091126630996906 1.0155971514226045 0.9242493354470406 0.9768115188289227 0.9106519370938111 0.9547519362097256 1.0 17.38004177519239 -6.137454951385103 0.9789558457056914 0.9439696941988633 1.1541793013150483 0.8302450963688436 0.035837170578825364 0.21648139592012594 0.431780505876513 0.015986505410460917 0.02911474048860642 7.286937567352592e-07 6.137454951385103 0.21020960711618497 T(ph)ISPAESTALLQGR ddPTM_PC-9_AZD4547_30min_R2 1 TISPAESTALLQGR 14 0 H0Y8J2;Q03188;Q03188-2 H0Y8J2 CENPC Centromere protein C 1 T(0.886)IS(0.087)PAES(0.023)T(0.004)ALLQGR 103.3 0.0030526999999999998 15095000.0 21500.0 16875.0 47692.0 70139.0 44009.0 36840.0 23381.0 64812.0 22084.0 31660.0 True False 28336.552772218856 22329.5137413892 47059.57291860075 53969.537186747744 37899.11000063597 34536.38897622311 25461.86370500126 54796.794631596655 23251.315154620424 30551.593036554015 0.927498370979054 0.7308788682368427 1.5403312312485788 1.7665048471343179 1.2404953795794178 1.130428417755546 0.8334054356686718 1.7935822386097517 0.7610508272613137 1.0 14.89895998728631 -6.731483162160187 6.894319798968427 1.1363125891900403 1.2592021452164381 0.027872781533472057 0.3753620957674006 1.024826369551239 158.7551127381151 0.1326603196896094 0.12992518555025484 1.8557387560677e-07 6.731483162160187 0.12288955602639784 T(ph)ISPSTSNNIPLMR ddPTM_PC-9_Lapatinib_30min_R1 1 TISPSTSNNIPLMR 14 0 Q15139;F8WBA3;O94806;O94806-2 Q15139;O94806 PRKD1;PRKD3 Serine/threonine-protein kinase D1;Serine/threonine-protein kinase;Serine/threonine-protein kinase D3 1 T(0.999)IS(0.001)PSTSNNIPLMR 108.97 0.0015515999999999998 3594900.0 8879.6 13328.0 13962.0 8749.0 11355.0 14312.0 11369.0 13400.0 13615.0 10917.0 True False 8752.975275680794 13297.139834869886 12814.098254878576 9392.430645808425 10687.121224788938 13699.909122901503 11957.631191055762 14022.612919105053 12081.53532769402 12803.988904011883 0.6836131569075492 1.0385154137944843 1.0007895469874646 0.7335550441523334 0.834671234480712 1.069971961519656 0.9338989029667988 1.0951753413900052 0.9435758979694604 1.0 13.644305711300817 -6.755041604376095 24.999516629122294 1.0098087882517404 0.8692384990986552 0.31552235261687656 0.11007925236002493 209.78367741052313 819735.7477159661 0.03724155070652394 0.03636944754063829 1.7577552171331493e-07 6.755041604376095 -0.14057028915308512 T(ph)ISQEFLTPGK ddPTM_PC-9_AZD4547_30min_R2 1 TISQEFLTPGK 11 0 E7ETM8;E7EUA0;Q0ZGT2-4;Q0ZGT2-2;Q0ZGT2;Q0ZGT2-3;H7BXY5 E7ETM8 NEXN Nexilin 1 T(0.879)IS(0.12)QEFLT(0.001)PGK 131.32 0.00040237 5368300.0 25768.0 29268.0 39757.0 34958.0 29302.0 38169.0 38430.0 51265.0 42430.0 36987.0 True False 33961.68799230397 38728.308633065426 39229.79620323768 26898.973195716033 25233.92308933708 35782.28639613083 41850.19555122528 43343.17220250576 44672.76317743822 35692.09638796663 0.9515184432751319 1.0850667949591897 1.0991171764420025 0.753639486549881 0.7069890996328403 1.0025268901883446 1.172533972124283 1.2143633069734352 1.2516149987900225 1.0 15.12331702063099 -7.170096943427545 4.045141393981576 1.178116533926996 0.9239350401612563 0.4205763278937419 0.13170314086612428 0.24395646882468108 7.237226848289622 0.05838813050706908 0.04404901996253298 6.75932076660642e-08 7.170096943427545 -0.2541814937657396 T(ph)ISQEFLTPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TISQEFLTPGK 11 0 E7ETM8;E7EUA0;Q0ZGT2-4;Q0ZGT2-2;Q0ZGT2;Q0ZGT2-3;H7BXY5 E7ETM8 NEXN Nexilin 1 T(0.997)IS(0.003)QEFLTPGK 148.96 0.00072575 2766600.0 22336.0 39023.0 34289.0 30771.0 31478.0 27814.0 36436.0 23737.0 29159.0 25181.0 True False 26117.043643891033 42896.94554597748 35106.57980175666 29047.00063092801 25310.111866713723 26355.384876251366 32984.51830620394 23113.92890143044 29585.395211591684 29746.11596731367 0.8779984476827017 1.4421024107185798 1.18020718537954 0.9764972564097484 0.8508711488426112 0.8860109637578167 1.1088680734805434 0.7770402336503036 0.994596916252912 1.0 14.860413683583143 -5.7947673956675265 4.453057322800866 0.930536879332813 1.1969385479609493 0.30798928358070576 0.1532325329697463 0.2036791229241527 9.08515750974252 0.041512518651763676 0.06641309139111623 1.6041043049155365e-06 5.7947673956675265 0.2664016686281363 T(ph)ISQEFLTPGK ddPTM_PC-9_Lapatinib_30min_R1 1 TISQEFLTPGK 11 0 E7ETM8;E7EUA0;Q0ZGT2-4;Q0ZGT2-2;Q0ZGT2;Q0ZGT2-3;H7BXY5 E7ETM8 NEXN Nexilin 1 T(0.953)IS(0.047)QEFLTPGK 130.15 0.00054629 4258000.0 28115.0 42517.0 33974.0 26683.0 39083.0 38103.0 30396.0 33961.0 30972.0 29964.0 True False 27714.07494434044 42418.554498736696 31180.788863432514 28645.356831878642 36784.21478013438 36473.42351243124 31969.756151229758 35538.95204072589 27483.607210381135 35143.2374754797 0.7886033540215875 1.2070189756516645 0.8872486174669627 0.8151029583391459 1.0466939708044722 1.0378504125546102 0.9096986631791064 1.011260048694213 0.7820454000448059 1.0 15.100959481387362 -8.217545033354373 24.998513003082294 0.891021692816012 0.96713481580555 0.04859132543727929 0.12619105143704706 1258.6051288008287 716797.2333290426 0.08174002309439224 0.03089448956644826 6.059753617869005e-09 8.217545033354373 0.0761131229895381 T(ph)ISQSSSLK ddPTM_PC-9_AZD4547_30min_R2 3 TISQSSSLK 9 0 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 T(0.991)IS(0.008)QSSS(0.001)LK;T(0.996)IS(0.004)QSSSLK;T(0.999)IS(0.001)QSSSLK 152.64 0.00022638 238438000.0 426190.0 421070.0 489560.0 685670.0 662930.0 630550.0 456040.0 522570.0 463430.0 598470.0 True False 561709.5546973012 557172.6430273631 483068.11452717887 527599.3749958981 570893.6125047511 591121.6088207791 496626.6765334588 441818.8139639808 487925.9636889041 577517.7474600904 0.9726273472420315 0.9647714645615574 0.8364558780257423 0.9135639161155962 0.9885299889319902 1.0235557459844622 0.8599331859801908 0.7650307127479452 0.8448674795446393 1.0 19.139505756513977 -7.441562364940342 9.708013938107293 0.845528027319027 0.9453735799378012 0.21676808651335333 0.07232690565764763 0.6121369511552569 69.98619349884007 0.03084179624376744 0.02075437532991788 3.6177423601132665e-08 7.441562364940342 0.09984555261877426 T(ph)ISQSSSLK ddPTM_PC-9_Lapatinib_30min_R1 1 TISQSSSLK 9 0 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 T(0.612)IS(0.381)QS(0.007)SSLK 124.39 0.0035708 88167000.0 86411.0 68787.0 82563.0 91896.0 138860.0 180740.0 128670.0 164130.0 221910.0 162370.0 True False 85178.7632941633 68627.72792776053 75774.98884239637 98654.33839606927 130692.52780926398 173010.1715255184 135331.90301285466 171756.078986023 196916.15898410426 190435.4381555744 0.44728420360803506 0.3603726732400288 0.39790382281943093 0.5180461123810084 0.6862826009437171 0.9084977733197925 0.7106445329902125 0.9019123785443155 1.0340310652854197 1.0 17.538942449374403 -6.492687457646283 0.7289621928974822 0.9685563489590779 0.3463257914960675 0.8945320905784441 0.07885520390949174 0.22431769829435871 0.26512920455587186 0.05377326927421436 0.07245017730253889 3.215974099070186e-07 6.492687457646283 -0.6222305574630105 down T(ph)ISVLASPSVPLLQHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TISVLASPSVPLLQHR 16 0 A0A1B0GTU4;A0A1B0GV30 A0A1B0GTU4 1 T(0.783)IS(0.217)VLASPSVPLLQHR 101.53 0.0034094 4721400.0 9762.7 7308.4 6803.4 6435.6 9216.8 8501.3 9479.9 10891.0 7105.9 5864.8 True False 11415.332287885696 8033.929652467055 6965.618858038181 6075.034196496708 7410.8342033523995 8055.476862316672 8581.89524346752 10605.122789968354 7209.810344457948 6928.041814268746 1.647699681080892 1.1596248792726196 1.0054239054521934 0.8768760869752238 1.0696867025382717 1.1627350235857268 1.2387187424002777 1.5307532884871486 1.0406707317511974 1.0 12.758231922153993 -7.1741258060162565 4.156753243425013 1.246602314612797 1.128452660590295 0.0 0.2316764403681743 0.8510065259247063 26.757519502607533 0.09566369924038587 0.07222369953856038 6.696905859777625e-08 7.1741258060162565 -0.118149654022502 T(ph)ISVSGSTAK ddPTM_PC-9_Lapatinib_30min_R1 1 TISVSGSTAK 10 0 Q8TDJ6-3;Q8TDJ6 Q8TDJ6-3 DMXL2 DmX-like protein 2 1 T(0.951)IS(0.049)VSGSTAK 99.34299999999999 0.008331700000000001 0.0 76539.0 63426.0 42054.0 46549.0 53983.0 63621.0 62448.0 51040.0 52487.0 37797.0 True False 75447.53982446653 63279.14099388183 38596.482453134464 49972.368742911895 50807.82607466148 60900.078137794604 65681.25187958938 53411.5047306807 46575.361347387145 44330.161088663284 1.7019459882757115 1.4274511853751066 0.8706596480878768 1.127276949049741 1.1461231998016528 1.3737842733300782 1.4816380149898958 1.2048569962074833 1.0506472388907704 1.0 15.436000984583496 -4.99337468424004 5.312000009767356 1.1793528340401431 1.6527334320861224 0.5131198634107099 0.167670020402085 0.14060776034591324 13.081903071056058 0.04588838448304595 0.16917106584287459 1.0153723101901823e-05 4.99337468424004 0.4733805980459793 T(ph)IT(ph)S(ph)WMDTK ddPTM_PC-9_Lapatinib_30min_R1 1 TITSWMDTK 9 0 Q86W56 Q86W56 PARG Poly(ADP-ribose) glycohydrolase 3 T(1)IT(1)S(0.998)WMDT(0.002)K 66.993 0.038383999999999995 0.0 11382.0 6390.9 9274.9 6633.2 6860.0 7801.3 6546.9 7977.6 9362.4 6217.0 True False 11219.69059279684 6376.102263705725 8512.353524149348 7121.02765570653 6456.508287278918 7467.65658471852 6885.86644777228 8348.268419660637 8307.90792155729 7291.600166368215 1.5387144572938263 0.8744448568525283 1.1674191302221615 0.9766069851925736 0.8854720692254802 1.0241451004352033 0.9443560111171013 1.14491582494693 1.1393806204400365 1.0 12.832019738275438 -4.751499233541743 24.99997596042311 1.0191605298183515 1.5387155083102557 0.712118804054093 0.09942921690560427 226.48938037903332 569593.3672579841 0.02493404417781293 0.32739054009821633 1.772151172687404e-05 4.751499233541743 0.5195549784919042 T(ph)ITGVPDNIQK ddPTM_PC-9_AZD4547_30min_R2 2 TITGVPDNIQK 11 0 Q5SYE7-2 Q5SYE7-2 NHSL1 NHS-like protein 1 1 T(0.974)IT(0.026)GVPDNIQK;T(1)ITGVPDNIQK 147.96 0.00018891 24398000.0 122577.0 106254.0 150730.0 182739.0 165346.0 170787.0 155233.0 192834.0 147539.0 156155.0 True False 161553.93624001273 140598.5275897818 148731.2217147676 140611.34683940603 142390.56197971254 160107.66189148254 169048.43627383196 163035.93618449225 155337.6103331618 150688.06097988316 1.072108401883147 0.933043578074521 0.9870139727567614 0.9331286495097819 0.9449359229509342 1.0625105987186132 1.1218435964638227 1.081943288169708 1.030855459437489 1.0 17.2012055911241 -6.774042159589374 22.690289853453823 1.0684529668342404 0.9702154437471737 0.43310405424828535 0.048195269334768254 62.80565390995747 113074.69058150357 0.016613090221297245 0.014777067627458264 1.682510721660909e-07 6.774042159589374 -0.09823752308706668 T(ph)ITGVPDNIQK ddPTM_PC-9_Lapatinib_30min_R1 1 TITGVPDNIQK 11 0 Q5SYE7-2 Q5SYE7-2 NHSL1 NHS-like protein 1 1 T(0.939)IT(0.061)GVPDNIQK 96.23 0.014403999999999998 9635800.0 52466.0 70834.0 80598.0 57619.0 62249.0 58435.0 55474.0 53138.0 79409.0 48801.0 True False 51717.82521891395 70669.98822502786 73971.54355727723 61856.49347134935 58587.636206242794 55935.87126863817 58346.17228363333 55606.985469806255 70465.12220615904 57236.187826754904 0.903586125886927 1.2347081611887745 1.2923911666021095 1.0807235041330738 1.0236117818254862 0.9772815659552206 1.0193930535736968 0.9715354495327329 1.23112885189779 1.0 15.804639965195673 -5.9912761087077175 24.93598096060203 1.0336998732198255 1.1583232804845989 0.13896711352732538 0.1166908928499184 324.8346951555511 928481.9986223785 0.03272620924828894 0.04845775260740271 1.0202906136335342e-06 5.9912761087077175 0.12462340726477339 T(ph)IVLGT(ph)PAY(ph)Y(ph)DGRLK ddPTM_PC-9_AZD4547_30min_R2 1 TIVLGTPAYYDGRLK 15 1 Q8N448 Q8N448 LNX2 Ligand of Numb protein X 2 4 T(1)IVLGT(1)PAY(1)Y(1)DGRLK 47.201 0.045292 0.0 2492.2 3740.8 3363.3 3202.6 3237.0 5889.7 3136.0 6236.5 3591.0 5078.6 True False 3284.6677590197123 4949.940444668959 3318.70044445882 2464.2900496767593 2787.59842468719 5521.416127938685 3415.0979247630103 5272.792225513064 3780.8129288282034 4900.799759805535 0.6702309663739554 1.0100270746147304 0.677175278957022 0.5028342659269439 0.5688047994839525 1.1266357326457623 0.6968450236984426 1.0759044408952325 0.7714685590374389 1.0 12.258801486003268 -6.7491898980999885 24.993498587629848 0.924081951263793 0.6931807797921864 0.34013089122655105 0.17252388908473906 296.85065603317497 605684.8309369024 0.05838948948706122 0.05798056760423898 1.7815995810501518e-07 6.7491898980999885 -0.2309011714716066 T(ph)KFASDDEHDEHDENGATGPVK ddPTM_PC-9_Lapatinib_30min_R1 1 TKFASDDEHDEHDENGATGPVK 22 1 P05455 P05455 SSB Lupus La protein 1 T(0.903)KFAS(0.089)DDEHDEHDENGAT(0.008)GPVK 49.559 0.025814 10365000.0 45786.0 42965.0 48245.0 40874.0 50785.0 48466.0 41127.0 44084.0 45717.0 44804.0 True False 45133.083243875946 42865.51718226175 44278.4823310856 43880.0103116669 47797.92614715161 46393.222159764155 43256.3548240435 46132.30357655425 40567.870038647634 52548.311702422674 0.8588874082094466 0.8157353831842611 0.8426242613051296 0.8350412960963666 0.9095996540826629 0.8828679867487589 0.8231730653688959 0.8779026781640138 0.7720109119467163 1.0 15.681356792877349 -11.777482872211898 2.482894246465478 1.6506193143299126 0.8482491844357726 0.6081201158164591 0.036958308282748195 2802017.576539867 1351051.6954491646 9994842.34707007 0.009173092992856543 1.6692336374655486e-12 11.777482872211898 -0.80237012989414 T(ph)KPIVKPQTSPEYGQGINPISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TKPIVKPQTSPEYGQGINPISR 22 2 O95793-2;O95793-3;O95793;A0A087X1A5 O95793-2 STAU1 Double-stranded RNA-binding protein Staufen homolog 1 1 T(0.541)KPIVKPQT(0.085)S(0.373)PEY(0.001)GQGINPISR 70.89699999999999 0.00080443 61755000.0 44965.0 55762.0 40930.0 52341.0 46301.0 50726.0 58000.0 47508.0 43437.0 33774.0 True False 52576.68640076823 61297.68284178043 41905.926427889404 49408.50346181153 37228.65142450954 48065.839261980596 52505.82011636371 46260.96533888686 44072.183950269515 39896.958845163106 1.317811881472323 1.5363998814965274 1.0503539026752124 1.2384027477773925 0.9331200297494089 1.2047494509173058 1.3160356487353981 1.1595110674580975 1.1046502095889092 1.0 15.283991160427771 -5.264012707851632 24.999714283189032 1.138296001534596 1.4271058880471248 0.5061679227888259 0.11851501515389526 170.46599582905333 1656083.010401531 0.030510280596317812 0.06854364715246135 5.444867204325476e-06 5.264012707851632 0.2888098865125288 T(ph)KPQDMIS(ph)AGGESVAGIT(ph)AISGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TKPQDMISAGGESVAGITAISGK 23 1 H0Y944;D6RBR1;P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;F8W7E0;P20810-2;E9PCH5;E9PSG1 H0Y944;P20810-6 CAST Calpastatin 3 T(0.999)KPQDMIS(0.998)AGGES(0.003)VAGIT(0.581)AIS(0.418)GK 56.36600000000001 0.02341 0.0 9578.4 12661.0 12655.0 13090.0 14561.0 13684.0 11826.0 9953.4 12189.0 10749.0 True False 11199.833937976618 13917.90040636602 12956.743194354758 12356.60973835259 11707.876577013096 12966.386950694752 10705.755667174431 9692.133796499036 12367.241065677536 12697.708610962814 0.882035828756302 1.0960954320805352 1.0204001045644016 0.9731369743108036 0.9220464050423138 1.0211595924874168 0.84312500744673 0.7632978589641869 0.9739742377612948 1.0 13.63228055577069 -7.261435605801956 24.999999815890355 0.8753740957755007 0.9889228159473968 0.20928411262563873 0.08277509836520457 0.4356227681373118 2879550.129725363 0.032432991884981444 0.023473321782645263 5.4772730817848384e-08 7.261435605801956 0.1135487201718961 T(ph)KSNSLSEQLAINTSPDAVK ddPTM_PC-9_AZD4547_30min_R2 2 TKSNSLSEQLAINTSPDAVK 20 1 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 T(0.424)KS(0.129)NS(0.199)LS(0.248)EQLAINTSPDAVK;T(0.807)KS(0.183)NS(0.01)LS(0.001)EQLAINTSPDAVK 148.36 0.00010412 27415000.0 116804.0 162603.0 160270.0 259360.0 186202.0 209520.0 158188.0 200976.0 173521.0 158652.0 True False 153945.2423258718 215161.23987502864 158144.71508144215 199568.55907205518 160351.06638047742 196418.6812784543 172266.42554923863 169919.77716903907 182692.9658098574 153097.6417699107 1.0055363397251733 1.4053857223901127 1.032966368738172 1.3035377734425542 1.0473777683752166 1.2829634670248578 1.1252062641705256 1.109878474969655 1.193310123512061 1.0 17.224092534981516 -13.24974114536592 0.25764745947470336 0.47905510963456627 1.1874984100512567 0.1371695622964172 0.12398788696716743 168.735107198265 3.0200603813273603 46.377568698131896 0.1547466330741442 5.626766001096721e-14 13.24974114536592 0.7084433004166903 T(ph)KSNSLSEQLAINTSPDAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TKSNSLSEQLAINTSPDAVK 20 1 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 T(0.496)KS(0.193)NS(0.281)LS(0.03)EQLAINTSPDAVK 84.125 0.00057645 9850900.0 114110.0 109810.0 71914.0 115570.0 126140.0 91236.0 110320.0 81838.0 83935.0 87375.0 True False 133426.5692247676 120711.21109099215 73628.70249536389 109094.9875829953 101423.77250356655 86451.42354820129 99869.69095236626 79689.83921452858 85162.39058558091 103215.3958398804 1.292700261807398 1.1695078055821564 0.7133499987694201 1.05696429001964 0.982641898316282 0.8375826381784621 0.9675852147803184 0.7720731831339641 0.8250938718260076 1.0 16.65529865687632 -5.080768802167883 5.524532818320576 0.896473349584096 1.265942290008484 0.6353160003616329 0.10380300245959898 0.1191332255713767 6.039472757332721 0.026349604111024227 0.0751308209113042 8.30292658406438e-06 5.080768802167883 0.36946894042438805 T(ph)KSNSLSEQLAINTSPDAVK ddPTM_PC-9_Lapatinib_30min_R1 1 TKSNSLSEQLAINTSPDAVK 20 1 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 T(0.351)KS(0.208)NS(0.287)LS(0.153)EQLAINTSPDAVK 86.91799999999999 0.00053595 10135000.0 74437.0 64751.0 46846.0 38252.0 55199.0 56110.0 64539.0 64949.0 56835.0 51812.0 True False 73375.514729926 64601.07303778959 42994.50271078943 41065.179684931296 51952.303345409484 53710.30609879843 67880.5136282477 67966.76764798176 50433.64380091735 60767.635164849664 1.2074768835560876 1.0630835454192125 0.707523052265478 0.6757738650439531 0.8549337686825222 0.8838636875220468 1.1170504404869848 1.11846984770104 0.8299425123933424 1.0 15.891015528560468 -7.232973341176667 22.815883145805795 1.026238172298189 0.8854216960708813 0.10592403558694397 0.1636427035495531 534.4035205187434 428330.6880521306 0.06846146016684712 0.053012171411741325 5.8482598212311944e-08 7.232973341176667 -0.14081647622730775 T(ph)KSPSLPPK ddPTM_PC-9_Lapatinib_30min_R1 1 TKSPSLPPK 9 1 P41970 P41970 ELK3 ETS domain-containing protein Elk-3 1 T(0.888)KS(0.088)PS(0.024)LPPK 78.548 0.015455000000000002 9280800.0 83995.0 93291.0 86049.0 78129.0 101520.0 95539.0 83597.0 77947.0 88937.0 79027.0 True False 82797.21589720338 93074.9904212819 78974.38337874568 83874.86729070373 95548.79319599933 91453.01968228677 87925.24361673753 81568.7021795136 78919.97851187101 92686.71165314167 0.893301902942167 1.0041891524816768 0.8520572363629517 0.9049287194974162 1.030879092502152 0.9866896564906553 0.9486283637483783 0.8800474277776233 0.8514702604534139 1.0 16.500074896325728 -10.895226354418508 3.6176801401788015 1.0003681070934594 0.931293973094844 0.11252521919728764 0.06001256868280177 46877350.21500241 138310.97516453685 143791.77538384465 0.015289905793979618 1.2728395037596753e-11 10.895226354418508 -0.0690741339986154 T(ph)KSPTDDEVTPSAVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TKSPTDDEVTPSAVVR 16 1 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 T(0.563)KS(0.343)PT(0.094)DDEVTPSAVVR;T(0.495)KS(0.495)PT(0.01)DDEVT(0.001)PSAVVR;T(0.557)KS(0.409)PT(0.033)DDEVTPSAVVR 86.539 0.0032153 21635300.0 41701.6 46984.0 41933.0 45566.0 47209.0 38411.0 38033.3 44371.0 40118.0 31793.0 True False 48760.85723585627 51648.261013561394 42932.841751788066 43013.08474696517 37958.73534264209 36396.65954129904 34430.51048675339 43206.3082649606 40704.649854200594 37556.819226750486 1.2983223350588091 1.3752032807073833 1.1431437122664643 1.1452802881754258 1.0107015483250863 0.9691092134707431 0.9167578936564913 1.1504251199789084 1.0838151550706405 1.0 15.196787262559523 -5.582529279611911 1.4558685930858464 1.0242145416999822 1.3486726945739127 0.7431271329880478 0.06978922023616518 0.2358822194801127 0.9567959788830932 0.023690104058835426 0.07118458417934705 2.6149941424332697e-06 5.582529279611911 0.32445815287393054 T(ph)KSPTDDEVTPSAVVR ddPTM_PC-9_Lapatinib_30min_R1 1 TKSPTDDEVTPSAVVR 16 1 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 T(0.92)KS(0.048)PT(0.032)DDEVTPSAVVR 60.968 0.031251 51840000.0 12508.0 14385.0 15439.0 12866.0 16464.0 16872.0 12175.0 4611.5 14104.0 13629.0 True False 12329.633626313731 14351.69241631176 14169.665016263458 13812.208559717821 15495.61988946941 16150.423890552984 12805.361927267479 4825.76712510843 12515.45899829574 15984.754490499025 0.7713370658049321 0.8978362742350582 0.8864487111569705 0.8640863747971534 0.9693999303323461 1.0103642129850934 0.8010984425740599 0.3018981072231517 0.7829622285243508 1.0 13.964408965515892 -7.531606581254519 24.993740130262182 0.6357577410513208 0.9011521773386801 0.19812546203407944 0.17344794261894747 226.92656929177076 649835.3702832144 0.07666073400290498 0.0443447440131846 2.9403120161449026e-08 7.531606581254519 0.26539443628735937 T(ph)KSSDDLLAGMAGGVTVTNGVK ddPTM_PC-9_AZD4547_30min_R2 1 TKSSDDLLAGMAGGVTVTNGVK 22 1 Q69YQ0-2;Q69YQ0;F8WAN1;C9J8U1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 T(0.701)KS(0.149)S(0.149)DDLLAGMAGGVTVTNGVK 137.42 2.9864e-05 14269000.0 44627.0 36707.0 41017.0 44434.0 54022.0 50357.0 42203.0 37116.0 37455.0 42984.0 True False 58817.45770073539 48571.81990549175 40473.08777996829 34190.42779845661 46521.97778759701 47208.168829415525 45958.98524195583 31380.575040831052 39434.79483410198 41479.143243311366 1.4180007854964525 1.170993808154996 0.9757455100400295 0.824279990497873 1.1215751857434717 1.1381182237178435 1.108002278937303 0.7565386502020208 0.9507138226742655 1.0 15.340098474968883 -4.907763127970613 2.3992103907450795 0.9852465965397262 1.4592480867956539 0.5709990157838563 0.1173728069711536 0.3320783707031964 2.9250442014940288 0.03391581304926004 0.2966478542689995 1.2366217252952207e-05 4.907763127970613 0.47400149025592764 T(ph)KSSDDLLAGMAGGVTVTNGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TKSSDDLLAGMAGGVTVTNGVK 22 1 Q69YQ0-2;Q69YQ0;F8WAN1;C9J8U1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 T(0.333)KS(0.333)S(0.333)DDLLAGMAGGVTVTNGVK;T(0.423)KS(0.423)S(0.153)DDLLAGMAGGVTVTNGVK 92.90100000000001 0.00012361 34574000.0 141228.0 124453.0 114499.0 169624.0 162403.0 149392.0 155456.0 139498.0 144560.0 115015.0 True False 165135.11101985324 136807.87135877664 117229.09039987568 160120.517208428 130581.29796969044 141557.62053041434 140730.0822760245 135836.32531034845 146673.916519349 135866.30904176077 1.2154235452815327 1.006930064735375 0.8628267833774992 1.1785152503054477 0.9611013862866776 1.0418890564466887 1.035798228924941 0.9997793144479761 1.079545897388486 1.0 17.0518282277879 -4.759470183354441 24.986023239638808 1.018095864151771 1.2154237970825117 0.3735513203775024 0.07650782272751554 54.10729874808899 686357.2246375859 0.018167434404540436 0.11520017444369335 1.7399221489255157e-05 4.759470183354441 0.1973279329307407 T(ph)KSSDDLLAGMAGGVTVTNGVK ddPTM_PC-9_Lapatinib_30min_R1 2 TKSSDDLLAGMAGGVTVTNGVK 22 1 Q69YQ0-2;Q69YQ0;F8WAN1;C9J8U1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 T(0.333)KS(0.333)S(0.333)DDLLAGMAGGVTVTNGVK;T(0.636)KS(0.182)S(0.182)DDLLAGMAGGVTVTNGVK 100.59 5.9475e-05 14040700.0 183119.0 137461.0 121971.0 140813.0 142304.0 156622.0 131731.0 135235.0 142325.0 117293.0 True False 180507.68948008816 137142.71750007852 111943.01520167543 151168.85775839764 133933.9585004285 149923.6421637142 138551.38661526667 141518.51179963953 126294.8597513076 137566.93876690188 1.3121444083737777 0.9969162556743217 0.8137348712204427 1.0988749121948793 0.9735911818708911 1.0898232053978458 1.0071561369118847 1.0287247289803645 0.9180611336078789 1.0 17.069774265639026 -4.761757967498723 8.766537719202336 0.9933531988726515 1.3147067209997774 0.6050642365159218 0.07762104694967621 0.056882510113794575 54.40474425946013 0.019128401213208697 0.10924311320597041 1.73078065529133e-05 4.761757967498723 0.32135352212712587 T(ph)LAYT(ph)MPSHVKAEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLAYTMPSHVKAEPK 15 1 G3V2D8;Q68DK2-4;Q68DK2-5;Q68DK2-2;Q68DK2 G3V2D8 ZFYVE26 Zinc finger FYVE domain-containing protein 26 2 T(0.682)LAY(0.636)T(0.682)MPSHVKAEPK 48.70399999999999 0.042357 5142600.0 20478.0 22667.0 24216.0 32972.0 33022.0 32519.0 34082.0 36365.0 32755.0 33040.0 True False 23944.52094106378 24917.229959015738 24793.401279691425 31124.685736666288 26551.576150410452 30813.646393572257 30853.506227688074 35410.45728190243 33233.979908628084 39029.89045550391 0.613491881776142 0.6384140377596669 0.6352413750163399 0.7974576759868193 0.6802882570393227 0.7894884160308214 0.7905096803400631 0.9072650952549349 0.8515007221584835 1.0 15.252291793145606 -6.646610396030259 0.22257863084417345 1.0443494097384076 0.46498365045645185 0.871932038205106 0.04352961694743251 1.5149347866893226 0.1626410186287906 0.1027878113547188 0.2712242470297707 2.2562623891495607e-07 6.646610396030259 -0.5793657592819558 T(ph)LCGTPNYIAPEVLSK ddPTM_PC-9_AZD4547_30min_R2 3 TLCGTPNYIAPEVLSK 16 0 P53350 P53350 PLK1 Serine/threonine-protein kinase PLK1 1 T(1)LCGTPNYIAPEVLSK;T(1)LCGTPNYIAPEVLSK;T(1)LCGTPNYIAPEVLSK 176.28 2.4828e-05 14710900.0 39373.1 35431.0 51090.2 77867.0 56112.0 60158.0 59202.0 68943.0 57868.2 57479.0 True False 51892.9267886442 46883.37785903174 50412.710566256355 59915.96618315755 48321.817363622984 56396.31075004427 64470.86331052931 58289.443502532995 60926.99491172825 55466.677705245966 0.9355694073549359 0.8452530383769059 0.9088828221180514 1.0802155214984288 0.8711864377457165 1.0167602078087035 1.16233504471157 1.050891200159624 1.0984431992754067 1.0 15.75933369430948 -6.982603778781385 6.864722861660925 1.0833940418494596 0.9317656833481546 0.5092311477220587 0.06943902545738553 0.12851928014000877 26.461771295128827 0.02518547009413638 0.021688265199432243 1.0408693523093459e-07 6.982603778781385 -0.15162835850130507 T(ph)LCGTPNYIAPEVLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLCGTPNYIAPEVLSK 16 0 P53350 P53350 PLK1 Serine/threonine-protein kinase PLK1 1 T(1)LCGTPNYIAPEVLSK;T(1)LCGTPNYIAPEVLSK 162.15 1.9208e-12 3315900.0 40289.0 44501.0 55242.0 49645.0 57396.0 39710.0 45670.0 38227.0 41351.0 36488.0 True False 47109.13195597806 48918.76518313669 56559.17878645166 46863.55160126162 46149.66582063348 37627.53769454024 41343.80697783326 37223.58175485447 41955.680146593775 43102.98556115095 1.0929435941077335 1.1349275356746413 1.3121870341489497 1.0872460687154837 1.0706837408086305 0.8729682458111261 0.959186618736145 0.8635963674034769 0.9733822286409959 1.0 15.395500181696553 -6.444649666224509 2.1955641599262243 0.9274777069073947 1.1713885225739806 0.6838971844144202 0.07123973872957517 0.17103947358961807 1.6325107637606562 0.02492618101431537 0.02827950261218647 3.592115842074641e-07 6.444649666224509 0.2439108156665859 T(ph)LCGTPNYIAPEVLSK ddPTM_PC-9_Lapatinib_30min_R1 4 TLCGTPNYIAPEVLSK 16 0 P53350 P53350 PLK1 Serine/threonine-protein kinase PLK1 1 T(1)LCGTPNYIAPEVLSK;T(1)LCGTPNYIAPEVLSK;T(0.995)LCGT(0.005)PNYIAPEVLSK;T(1)LCGTPNYIAPEVLSK 180.1 1.1142000000000001e-05 12425600.0 48989.3 60759.0 77484.0 70711.3 61452.4 62184.0 57858.3 53857.8 66008.0 42735.700000000004 True False 48290.70359846267 60618.31626852186 71113.56461688937 75911.64488798186 57837.890652066904 59524.53527798398 60853.919671163865 56360.23000556537 58573.48394494511 50122.50880325915 0.9634534414071992 1.2094030749031508 1.4187949948001266 1.5145220520774452 1.153930480197872 1.1875809232061718 1.2141036257787423 1.1244495008577986 1.168606387498633 1.0 15.613171007845224 -8.281293395668133 0.6724152646324659 1.0106082282846842 1.2639700157684441 0.20564113018099062 0.14142915580263757 1.1575223297748216 1.1995585145636418 0.15005480404038898 0.0646666355600137 5.23246828085334e-09 8.281293395668133 0.2533617874837599 T(ph)LDNSDLQR ddPTM_PC-9_AZD4547_30min_R2 1 TLDNSDLQR 9 0 E7EUN2 E7EUN2 AGAP1 1 T(1)LDNSDLQR 90.913 0.011227 0.0 5244.9 8849.2 10616.0 14853.0 14466.0 10919.0 13186.0 18214.0 12145.0 12924.0 True False 6912.669099302825 11709.530844462288 10475.22490362882 11428.870326562455 12457.645601336091 10236.233203891972 14359.528455333246 15399.444816081923 12786.959905491094 12471.53469375944 0.554275738234671 0.9389005549029625 0.8399307030649931 0.9163964666097816 0.9988863365444272 0.8207677286913231 1.1513842368187877 1.2347674279242924 1.02529161161613 1.0 13.606351387527129 -3.9931789332069063 0.3811100427140704 1.098153933671189 1.1411188160740532e-17 0.578625638005452 0.11590905842987748 8.296442360814684 0.6009366849767057 0.09914666518187991 4.69062056285722 0.00010158300755721444 3.9931789332069063 -1.098153933671189 T(ph)LDNSDLQR ddPTM_PC-9_Lapatinib_30min_R1 1 TLDNSDLQR 9 0 E7EUN2 E7EUN2 AGAP1 1 T(1)LDNSDLQR 94.76700000000001 0.013793999999999999 4128000.0 13850.0 11166.0 10736.0 9581.5 13898.0 12342.0 9026.3 12695.0 14672.0 8561.9 True False 13652.496460221058 11140.14581303699 9853.327522158454 10286.155472947019 13080.546964519295 11814.161430607206 9493.6376479749 13284.856045376013 13019.484856990572 10041.813006985374 1.359564896371202 1.1093759468820605 0.9812299348040234 1.0243325050756944 1.302608100292257 1.1764968559351718 0.9454107183006547 1.3229539363195355 1.2965273151306287 1.0 13.293732144859394 -6.239173812020948 24.976613086930406 1.1788426416796611 1.1081511418372982 0.0295344562733707 0.14925188079341428 3032.4690497359466 3401700.211468384 0.04556449936959994 0.058783147908529745 5.765356778520113e-07 6.239173812020948 -0.07069149984236289 T(ph)LGSRGYIPIYTPFFMRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLGSRGYIPIYTPFFMRK 18 2 Q5T5C7;P49591 Q5T5C7 SARS Serine--tRNA ligase, cytoplasmic 1 T(0.713)LGS(0.156)RGY(0.131)IPIYTPFFMRK 54.236999999999995 0.044962 0.0 11047.0 15986.0 15969.0 35888.0 18930.0 31267.0 24098.0 20236.0 33754.0 21494.0 True False 12917.038911804448 17572.984432206547 16349.76152276974 33877.31171046582 15220.802390142018 29627.30347759229 21815.26298558849 19704.826441814294 34247.58839370575 25390.692053589624 0.5087312659513861 0.6921034052603602 0.643927368669665 1.334241368410295 0.5994638648689439 1.1668568708194669 0.8591834732013279 0.7760649611371467 1.3488245346532008 1.0 14.63201209744448 -5.56824117921945 24.444484637578764 0.9859098741985152 0.6173166241016599 0.3894908642179895 0.2264511110393819 100.8815571987893 54361.54455080516 0.057812312720946245 0.10013394157875398 2.7024571764344483e-06 5.56824117921945 -0.3685932500968553 T(ph)LHSPPLQLQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLHSPPLQLQQR 12 0 A0A2R8YGT1;F8W9A8;B7WPL9;Q6PFW1-7;Q6PFW1-4;Q6PFW1-3;Q6PFW1-2;Q6PFW1 A0A2R8YGT1 PPIP5K1 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 1 T(0.973)LHS(0.027)PPLQLQQR 74.133 0.044391 5674900.0 18891.0 20886.0 20693.0 21807.0 26052.0 20641.0 23478.0 22546.0 19245.0 17374.0 True False 22088.873185742534 22959.42404923471 21186.399598639502 20585.224489247914 20947.2976158468 19558.54962359621 21253.99387399977 21954.191389461615 19526.42171703701 20523.76866749167 1.076258144574095 1.118674860412014 1.032286026113586 1.002994373146175 1.020636022322059 0.9529706722223825 1.0355794892418921 1.0696959094182172 0.9514052722668623 1.0 14.325008049026758 -5.417743054140835 4.078880430637058 1.0079040599988656 1.0967909182494233 0.5244738814443317 0.03467640013879323 0.17759455312389008 5.066772655299123 0.009240433403917355 0.020326317132920515 3.821703110963824e-06 5.417743054140835 0.08888685825055775 T(ph)LIPCY(ph)EEY(ph)KK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLIPCYEEYKK 11 1 E9PDS3;Q13797 E9PDS3 ITGA9 Integrin alpha-9 3 T(1)LIPCY(1)EEY(1)KK 47.198 0.045594 0.0 14974.0 17512.0 19654.0 17674.0 22879.0 18037.0 18597.0 14785.0 17027.0 12897.0 True False 17508.802450018997 19250.475627223885 20122.62589821007 16683.783079881112 18396.02418827572 17091.107967676217 16835.357529379584 14396.909416002396 17275.98766308075 15235.12400740418 1.1492392475118562 1.263558840602037 1.3208048643667485 1.0950867923210137 1.207474529208647 1.1218227012376165 1.1050358054977236 0.9449814395344326 1.1339577974347121 1.0 13.895113622543256 -6.954002383329562 0.8961398046754279 1.0237516756420406 1.2306588435399366 0.5287667204092343 0.07313257791020308 0.4452866412070269 0.750125029806445 0.048792205004040246 0.037277447643707454 1.1117256263157016e-07 6.954002383329562 0.20690716789789598 T(ph)LMS(ph)S(ph)GQMAPS(ph)SSNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLMSSGQMAPSSSNK 15 0 J3KN16;R4GMY1;Q5VYK3 J3KN16 KIAA0368;ECM29 Proteasome-associated protein ECM29 homolog 4 T(0.999)LMS(0.999)S(0.999)GQMAPS(0.396)S(0.33)S(0.276)NK 49.223 0.044941 0.0 0.0 1057.6 706.6 562.6 1093.8 502.81 738.82 648.38 618.02 1026.6 True False 0.0 1162.591538565097 723.4480237954228 531.07934597381 879.4777419089988 476.44175845358325 668.833621006411 631.3607120153963 627.0573733210296 1212.714453438872 0.0 0.9586688237023626 0.5965526523939372 0.4379261288325855 0.7252141997772683 0.3928721696212543 0.5515178112290259 0.5206177845287969 0.5170692668359765 1.0 10.244024177162006 -10.809000376955172 5.575767078741993 1.0000483528934268 0.5377848847309016 0.27462165726318843 0.23169444890595495 0.00012908624306689549 1.6527228329689306e-05 0.20793837905950427 0.05042720917930192 1.5523856625312026e-11 10.809000376955172 -0.46226346816252517 T(ph)LPPNVK ddPTM_PC-9_Lapatinib_30min_R1 1 TLPPNVK 7 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 T(1)LPPNVK 79.906 0.031039999999999998 0.0 28567.0 35665.0 36927.0 32970.0 34436.0 39145.0 27152.0 32534.0 34645.0 22457.0 True False 28159.629341453798 35582.41988375105 33891.00460234215 35394.723784695816 32410.54218378087 37470.85960145186 28557.79770424365 34045.64841120624 30742.91527197646 26338.66252792844 1.069136646995438 1.3509577354590767 1.2867397714825313 1.3438314776676568 1.2305310548481365 1.4226561262068373 1.084253905222489 1.2926111329725123 1.167216263900186 1.0 14.68489446723516 -8.868730073561869 0.7430422269831751 0.9977567983209328 1.277177920253401 0.35958379905628757 0.10602593083058331 1.2833525005031106 1.3305906342929836 0.10368191807127972 0.03646862925772167 1.3529131761570696e-09 8.868730073561869 0.27942112193246826 T(ph)LPSPIDAK ddPTM_PC-9_AZD4547_30min_R2 1 TLPSPIDAK 9 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 T(0.744)LPS(0.256)PIDAK 96.34200000000001 0.012556999999999999 4749700.0 47122.0 42662.0 55408.0 100020.0 97742.0 75103.0 78869.0 92327.0 71497.0 86838.0 True False 62105.81580151149 56451.65719911973 54673.25371705592 76961.93429359561 84172.21044972992 70406.79753749419 85888.18821050187 78059.98361339605 75276.18545598161 83797.82805143022 0.7411387293164038 0.6736649208195825 0.6524423721758119 0.9184239745015929 1.0044676861800037 0.8401983580562805 1.0249452785075612 0.9315275279627461 0.8983071185303453 1.0 16.354625230872188 -5.800183328851067 6.483540156584809 0.9451721918023205 0.6873987039860229 0.8163243140021521 0.05575934126325936 0.06876696627517126 7.778114325191705 0.015108363638249852 0.023041858117727503 1.5842243022440114e-06 5.800183328851067 -0.2577734878162976 T(ph)LRVQGNDHS(ph)ATRERR ddPTM_PC-9_AZD4547_30min_R2 1 TLRVQGNDHSATRERR 16 3 H7C0L5;B7ZKJ8;Q14624-4;Q14624-3;Q14624-2;Q14624 H7C0L5 ITIH4 Inter-alpha-trypsin inhibitor heavy chain H4;70 kDa inter-alpha-trypsin inhibitor heavy chain H4;35 kDa inter-alpha-trypsin inhibitor heavy chain H4 2 T(1)LRVQGNDHS(0.721)AT(0.279)RERR 76.051 0.043476999999999995 0.0 3633.4 3061.1 5996.7 15271.0 8533.7 5838.4 5405.5 7096.5 3488.0 7848.9 True False 4788.745620585114 4050.5407119269003 5917.179839825829 11750.506884598073 7348.943057384335 5473.323925048343 5886.579028158946 5999.898986347061 3672.36855910687 7574.112400019224 0.6322517237231599 0.5347875101400158 0.7812373948676561 1.5514038165803097 0.9702711907689252 0.7226356879829842 0.777197210348239 0.7921586939126798 0.48485794310334623 1.0 12.886861115674108 -6.771588297779292 24.56926445633971 0.7437439984644165 0.9042935354868256 0.05627414665142472 0.28024754282867165 560.8074879475749 1357635.1948348272 0.10804906323012274 0.09639965924284799 1.692044194626949e-07 6.771588297779292 0.16054953702240904 T(ph)LRY(ph)LS(ph)LLY(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 1 TLRYLSLLYPAR 12 1 Q9UKK3 Q9UKK3 PARP4 Poly [ADP-ribose] polymerase 4 4 T(1)LRY(1)LS(1)LLY(1)PAR 47.622 0.034956 2805400.0 6267.4 8237.4 6650.7 6920.7 8963.0 6311.1 9020.0 11774.0 7403.6 7992.0 True False 6178.025726699603 8218.326806404351 6103.905118444416 7429.67136477842 8435.813961935995 6041.188964892657 9487.011464801042 12321.063023100207 6569.728604635728 9373.40655132938 0.659101436907525 0.8767705488287809 0.6511938946656198 0.7926330010432235 0.8999731224438983 0.6445030343889082 1.0121199174333848 1.3144701401384085 0.7008901799638657 1.0 13.19435774253041 -7.3301401892112645 7.826530037246385 1.0346093601039337 0.7635234405429242 0.3646577986419781 0.16162967304136208 0.31965643933270743 33.034912950375684 0.06436911301461427 0.04330014880031029 4.6758418187771893e-08 7.3301401892112645 -0.27108591956100947 T(ph)LSADASVNTLPVVVSR ddPTM_PC-9_AZD4547_30min_R2 1 TLSADASVNTLPVVVSR 17 0 Q92615;H0Y4V9;H0Y641 Q92615 LARP4B La-related protein 4B 1 T(0.994)LS(0.006)ADASVNTLPVVVSR 212.41 4.909e-18 7145800.0 12088.0 12296.0 15307.0 22515.0 15280.0 15638.0 12725.0 16933.0 12424.0 13986.0 True False 15931.732553980528 16270.441538614608 15104.019178583869 17324.514603282416 13158.635751998854 14660.15338789839 13857.500348408594 14316.393931630339 13080.707275901303 13496.35439700709 1.1804471107778187 1.2055434423256322 1.1191184474181628 1.2836440192415404 0.97497704675841 1.0862306187772737 1.026758778020944 1.0607600771661048 0.9692030077990572 1.0 13.720282142111788 -6.269996622179179 24.99860788385683 1.0263769005276806 1.1922086407629566 0.7477715740033151 0.05038861474598472 317.53375966068353 927622.3993081045 0.014744862512940339 0.016986109666951087 5.370359732693689e-07 6.269996622179179 0.16583174023527603 T(ph)LSADASVNTLPVVVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLSADASVNTLPVVVSR 17 0 Q92615;H0Y4V9;H0Y641 Q92615 LARP4B La-related protein 4B 1 T(0.943)LS(0.057)ADASVNTLPVVVSR 213.36 8.093999999999999e-22 6088300.0 13361.0 11342.0 18899.0 16607.0 20887.0 16820.0 18425.0 21663.0 13479.0 15542.0 True False 15622.75340822117 12467.95880333334 19349.623834856633 15676.563630620447 16794.342288584066 15937.929590082276 16679.650614551734 21094.369203845778 13676.104875237297 18359.641569595697 0.8509291071397099 0.6790959810446834 1.0539216553606574 0.8538600043576813 0.9147423834458822 0.8680959009829542 0.9084954382864372 1.1489532147936319 0.7449004286600821 1.0 14.164250273224132 -5.254543535853894 24.9992286012955 0.9347519297807847 0.7650125477487829 0.2701496103069102 0.11279368970422142 679.3166355638808 2462684.0762173072 0.027254041703841294 0.06881659454657313 5.5648884623312286e-06 5.254543535853894 -0.16973938203200178 T(ph)LSADASVNTLPVVVSR ddPTM_PC-9_Lapatinib_30min_R1 1 TLSADASVNTLPVVVSR 17 0 Q92615;H0Y4V9;H0Y641 Q92615 LARP4B La-related protein 4B 1 T(0.985)LS(0.015)ADASVNTLPVVVSR 189.56 3.5976e-08 5074200.0 13250.0 9205.3 10107.0 8807.2 10876.0 13187.0 12003.0 10637.0 13691.0 10788.0 True False 13061.052570247586 9183.98569342195 9276.041474148242 9454.910867957935 10236.295063038704 12623.022750398415 12624.456608869941 11131.23385227764 12148.975407378544 12652.691425893574 1.0322746466035129 0.7258523411569999 0.7331279300121822 0.7472647952678731 0.8090211575135907 0.997655149051178 0.9977684734359481 0.8797522580450915 0.9601890221171299 1.0 13.627156680973597 -6.734350511716144 9.992097520688406 0.9614632851308905 0.7969912483417334 0.4396691082140568 0.08826328102176834 0.34732081323373115 123.20576133307776 0.02953215778704931 0.029224798535804373 1.8435269392472893e-07 6.734350511716144 -0.16447203678915712 T(ph)LSDDLDEAAKEFQEK ddPTM_PC-9_AZD4547_30min_R2 1 TLSDDLDEAAKEFQEK 16 1 A0A087WV29;Q9H0A0-2;Q9H0A0 A0A087WV29 NAT10 N-acetyltransferase 10 1 T(0.5)LS(0.5)DDLDEAAKEFQEK 61.684 0.029176999999999998 2275700.0 11900.0 9326.2 9295.9 16049.0 10962.0 11594.0 11878.0 12469.0 10910.0 13859.0 True False 15683.952464623459 12340.71176621889 9172.630292166845 12349.151004578252 9440.115517893417 10869.025347185961 12935.118989265004 10542.202559115265 11486.680326793565 13373.800628351291 1.1727371224134182 0.9227527842801587 0.6858656373807209 0.9233838119583695 0.7058663262768546 0.8127102870177813 0.9671984313751231 0.7882727469980908 0.8588942400145254 1.0 13.7071218949798 -4.817419133373783 3.648182702261233 0.8349188417757374 1.1972100921072455 0.5040898017267836 0.09774675739842612 0.18615948599672855 4.215723633855735 0.023339970835134644 0.17228026141448302 1.5225826148537319e-05 4.817419133373783 0.3622912503315081 T(ph)LSDDLDEAAKEFQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLSDDLDEAAKEFQEK 16 1 A0A087WV29;Q9H0A0-2;Q9H0A0 A0A087WV29 NAT10 N-acetyltransferase 10 1 T(0.5)LS(0.5)DDLDEAAKEFQEK 66.60600000000001 0.019048 2763000.0 19611.0 16251.0 16908.0 21736.0 25865.0 18924.0 22990.0 24985.0 19707.0 18151.0 True False 22930.754965094326 17864.291880882567 17311.15084394707 20518.202389062786 20796.93892345608 17931.592126201955 20812.220766813803 24329.170223795743 19995.177593018874 21441.632616763065 1.0694500449171518 0.8331591255283549 0.8073616012995771 0.9569328397606094 0.9699326210447723 0.8362978904965958 0.9706453393172502 1.134669670852172 0.9325398839912333 1.0 14.388127139749697 -7.522163398786261 24.9996643500332 1.0306943791977972 0.9080721531625864 0.24667143823568138 0.08634253933835322 34.296574002071104 1198733.1983240996 0.03931352943427001 0.023048341495332702 3.004945510391884e-08 7.522163398786261 -0.12262222603521078 T(ph)LSDESIYNSQR ddPTM_PC-9_AZD4547_30min_R2 4 TLSDESIYNSQR 12 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 T(0.999)LS(0.001)DESIYNSQR;T(0.999)LS(0.001)DESIYNSQR;T(1)LSDESIYNSQR;T(0.989)LS(0.01)DES(0.001)IYNSQR 246.63 2.0603e-29 287520000.0 65660.0 63339.0 82567.0 102366.0 95953.0 90623.0 67615.0 91558.0 67524.8 80981.0 True False 86538.5141871578 83812.09308834671 81472.1076316805 78767.10023893439 82631.58221934206 84956.3294840462 73632.60401238874 77409.81489353391 71094.02307338869 78145.87983869785 1.1073970165258018 1.0725081509267613 1.0425643399223141 1.0079494965252016 1.0574016491963905 1.0871504634589297 0.9422455050013508 0.990580886072519 0.9097603510272709 1.0 16.253882190164347 -7.265015441830521 24.995748494754952 0.9598617556003121 1.0593335002582045 0.6823954708016102 0.033996967984428056 193.08832711544147 1349626.3987303707 0.014094240695555604 0.009914128086247047 5.432310159570897e-08 7.265015441830521 0.09947174465789244 T(ph)LSDESIYNSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLSDESIYNSQR 12 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 T(0.997)LS(0.003)DESIYNSQR 248.67 1.3585e-29 50297000.0 20227.0 20532.0 23485.0 25604.0 23607.0 26538.0 22684.0 19119.0 22400.0 17613.0 True False 23651.031598539743 22570.281268739196 24044.971467358482 24169.490889287998 18981.377814267446 25146.300562521013 20535.20730206198 18617.146508254988 22727.557623363416 20806.09747556871 1.1367355952413305 1.0847916720202844 1.1556694615889875 1.1616542178401648 0.9122988026253401 1.2086024585844959 0.9869802506777247 0.8947928139871464 1.0923508192755012 1.0 14.344718768907914 -6.7665671535487775 0.8129569193861612 0.9912774737606257 1.1294595472377824 0.23282940088465176 0.09062091974105964 0.9237338097649472 1.3329471051018305 0.06023308792896663 0.05717311205887753 1.7117204784464517e-07 6.7665671535487775 0.13818207347715672 T(ph)LSDESIYNSQR ddPTM_PC-9_Lapatinib_30min_R1 4 TLSDESIYNSQR 12 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 T(0.997)LS(0.003)DESIYNSQR;T(0.989)LS(0.011)DESIYNSQR;T(0.867)LS(0.128)DES(0.004)IYNS(0.001)QR;T(1)LSDESIYNSQR 234.04 3.7483e-21 295864000.0 91877.0 60332.0 87851.0 67145.0 77805.0 76895.0 65650.6 67672.0 75467.0 53361.9 True False 90566.81713182155 60192.30496078704 80628.22989466698 72083.06728915391 73228.66287051543 73606.38010099996 69049.66683714707 70816.28816878202 66967.1117572593 62585.433314737675 1.447090997618687 0.9617622148285566 1.288290671236442 1.1517547050709598 1.1700592133356928 1.176094439273732 1.1032865505604352 1.1315139069606175 1.0700111545203574 1.0 15.933539290221054 -1.522878745873282 0.0674054479201901 0.8123789071459853 1.912175506010179 0.30709548398064 0.11022089830237758 365.83765865019103 1.833770569028899 5.436978701304629 38.47004386419536 0.02999999995904085 1.522878745873282 1.0997965988641938 T(ph)LSDESLCSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TLSDESLCSGR 11 0 O60292;M0R2Q7 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 T(0.958)LS(0.04)DES(0.002)LCSGR;T(0.986)LS(0.014)DESLCSGR;T(0.9)LS(0.099)DES(0.001)LCSGR 173.04 0.00059709 56635000.0 50664.1 54352.0 62383.0 65824.0 74363.0 66016.0 60738.0 53214.0 53183.0 44975.0 True False 59240.53146841241 59747.70736014573 63870.44730884499 62136.0946842874 59792.10396926209 62554.00474547396 54984.456934960326 51817.18888489356 53960.70076264893 53128.61147809586 1.1150400851871765 1.1245862765447734 1.202185517970441 1.1695410995242213 1.1254219206145353 1.177407107115232 1.0349311868922004 0.9753160762776009 1.0156617924203821 1.0 15.697201387865004 -7.3805045241826415 4.0678357439357615 0.9978587383473346 1.1528038983560829 0.8752538975718975 0.027193821435031858 0.07989413488994043 2.2558940452642653 0.01257720722326986 0.008179695908246975 4.163853833846589e-08 7.3805045241826415 0.15494516000874825 T(ph)LSDESLCSGR ddPTM_PC-9_Lapatinib_30min_R1 2 TLSDESLCSGR 11 0 O60292;M0R2Q7 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 T(0.995)LS(0.004)DES(0.001)LCSGR;T(0.798)LS(0.16)DES(0.042)LCSGR 168.85 0.0054825 58495200.0 64926.0 61384.0 63883.0 53555.0 66765.0 59884.0 58077.0 55949.0 69372.0 56421.0 True False 64000.14333402981 61241.86911942168 58630.78633551127 57493.61335424279 62838.01396504041 57322.90091642215 61083.94288705656 58548.59479186633 61558.59484045463 66173.29467374313 0.9671596925855407 0.9254771040397027 0.8860188483070248 0.8688340763098751 0.9495977837412087 0.8662542978862329 0.9230905486604708 0.8847767831499221 0.9302634113045066 1.0 16.013961490616026 -10.44904927306551 5.682172829119364 1.0000000719466056 0.9090725611778163 0.40129014953699416 0.03241199079120983 2.8816192867808124e-08 5.463778071582894e-09 0.030639249427582674 0.007431103641765466 3.555909725549723e-11 10.44904927306551 -0.09092751076878924 T(ph)LSFDTSK ddPTM_PC-9_Lapatinib_30min_R1 1 TLSFDTSK 8 0 Q7L804;Q7L804-2 Q7L804 RAB11FIP2 Rab11 family-interacting protein 2 1 T(0.985)LS(0.015)FDTSK 105.2 0.009403700000000001 8169500.0 73972.0 74548.0 63972.0 48507.0 49188.0 56019.0 39423.0 46232.0 62252.0 41554.0 True False 72917.14571519647 74375.38868621556 58712.46909906116 52074.366594608444 46294.85854732879 53623.197956667114 41464.13004177954 48380.107498213816 55240.524217378515 48736.55353277547 1.4961489976134543 1.5260699268814302 1.2046906242472986 1.0684868506261587 0.9499001302214644 1.1002665159858989 0.850780923888982 0.9926862691609504 1.1334515925552493 1.0 15.5727166122074 -5.462978895325488 1.9680224082942823 1.0025759657891518 1.5327576872080009 0.8709121310742907 0.0759873993699365 0.11124060400062714 0.8258427960445334 0.022088145628018478 0.0632354096259667 3.4436666496120023e-06 5.462978895325488 0.5301817214188491 T(ph)LSGSGSGSGSSYSGSSSR ddPTM_PC-9_AZD4547_30min_R2 2 TLSGSGSGSGSSYSGSSSR 19 0 E7ERS3;Q86VM9 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 T(0.975)LS(0.024)GS(0.001)GSGSGSSYSGSSSR;T(1)LSGSGSGSGSSYSGSSSR 214.81 6.920999999999998e-75 0.0 10327.7 9905.2 15300.0 16095.7 17413.1 13148.6 13309.8 14613.0 11070.099999999999 17269.2 True False 13611.69377049511 13106.862193256786 15097.112003157592 12385.085041086068 14995.59163698503 12326.415963430161 14494.346415500868 12354.896623333983 11655.242885942927 16664.6105643354 0.8168023919878478 0.7865087601451249 0.9059384823229849 0.7431967877840413 0.8998465088093746 0.7396762088044481 0.8697680848612688 0.7413852592376322 0.6994008555403497 1.0 14.024499983018204 -6.780015342226711 24.99765544816357 0.7976153275908714 0.827362425945505 0.0026690385985116416 0.09089717433025747 1221.347462006814 1643554.0674488065 0.030237701139960712 0.02671337111559073 1.6595282806073678e-07 6.780015342226711 0.029747098354633628 T(ph)LSMIEEEIR ddPTM_PC-9_AZD4547_30min_R2 1 TLSMIEEEIR 10 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 T(0.997)LS(0.003)MIEEEIR 203.03 0.00021761 6620600.0 4952.9 5347.9 8342.1 7323.9 7623.9 6407.3 5071.7 7215.5 5922.6 5213.9 True False 6527.819173280126 7076.504091115567 8231.478303368689 5635.488008127026 6565.453083093195 6006.650518114939 5523.071474815231 6100.51027069502 6235.656544772463 5031.362947987648 1.2974256162320794 1.4064785554669428 1.6360334939980754 1.1200718505869278 1.3049054800785391 1.1938416250645103 1.0977286933800408 1.2124965608245355 1.23935732906458 1.0 12.296733549891762 -5.78092863549566 24.99998766268822 1.1797573376727388 1.442629226935565 0.5703423862495516 0.11085328478996166 172.44569360218608 221205.40420875204 0.030893605834571874 0.0458974071074411 1.6560420666544795e-06 5.78092863549566 0.2628718892628261 T(ph)LSMIEEEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLSMIEEEIR 10 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 T(0.825)LS(0.175)MIEEEIR 114.71 0.0028973000000000002 1621500.0 1218.4 2298.0 2177.0 3146.9 3135.3 2890.9 4268.6 3798.2 3219.5 2297.5 True False 1424.6510555030816 2526.130253047081 2228.9079363184765 2970.5893953874534 2520.9604719393706 2739.2961148614054 3864.247306012242 3698.5012745255544 3266.5790968044 2714.018563000007 0.5249231066158622 0.9307711772813968 0.8212574396892476 1.0945354007099493 0.9288663336011841 1.0093136989577025 1.4238101974294537 1.3627398592430133 1.2035949721705685 1.0 11.406214873015195 -4.924330695910179 0.4668484566877873 1.251514399047385 0.23689226847211067 0.6108058001327606 0.15536111055967766 2.965690689251819 0.553060012607617 0.1142343400937393 1.644378501978332 1.1903352755426038e-05 4.924330695910179 -1.0146221305752743 T(ph)LSPEFNER ddPTM_PC-9_AZD4547_30min_R2 2 TLSPEFNER 9 0 Q9BSJ8;Q9BSJ8-2 Q9BSJ8 ESYT1 Extended synaptotagmin-1 1 T(0.996)LS(0.004)PEFNER;T(0.976)LS(0.024)PEFNER 181.53 0.0042722 15148200.0 45858.0 52564.0 83626.0 76359.0 79701.0 54558.0 60795.0 77062.0 59056.0 54453.0 True False 60439.89009434477 69554.28505495604 82517.06459974237 58755.61228478978 68635.89188940203 51146.47963530894 66205.63722447946 65153.83860859254 62177.57959478651 52546.617044203274 1.1502146759229337 1.3236681820343557 1.5703592208481727 1.1181616551140365 1.306190498080288 0.9733543758351464 1.259940999984565 1.2399245141468158 1.1832841597106332 1.0 15.68131026589382 T(ph)LSPEFNER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLSPEFNER 9 0 Q9BSJ8;Q9BSJ8-2 Q9BSJ8 ESYT1 Extended synaptotagmin-1 1 T(0.995)LS(0.005)PEFNER;T(0.915)LS(0.085)PEFNER 161.67 0.00038219 11413200.0 46179.0 49528.0 50047.0 55223.0 64858.0 58165.0 53263.0 48096.0 42404.0 37716.0 True False 53996.19262317531 54444.8125208511 51240.31028430444 52129.034345381595 52149.5404870487 55114.725006369496 48217.5430492738 46833.53096192432 43024.07827951349 44553.61224030829 1.2119374817901787 1.2220066967228775 1.1500820631092756 1.1700293584325743 1.1704896161004934 1.237042794848998 1.0822364478373472 1.0511724775382714 0.9656698102828346 1.0 15.443254784358706 -7.627901851529974 1.951861735457992 0.9922814270808523 1.1908039814123907 0.8797817548744175 0.03149802257189928 0.11128894093510554 0.8378004714464148 0.020716273418748602 0.009576620154756549 2.3555815738845376e-08 7.627901851529974 0.19852255433153843 T(ph)LSPEFNER ddPTM_PC-9_Lapatinib_30min_R1 2 TLSPEFNER 9 0 Q9BSJ8;Q9BSJ8-2 Q9BSJ8 ESYT1 Extended synaptotagmin-1 1 T(1)LSPEFNER;T(0.591)LS(0.409)PEFNER 166.86 0.0026735 10393800.0 59339.0 56480.0 46878.0 36373.0 25459.2 41991.0 38010.0 41535.0 52248.0 21913.4 True False 58492.81497856012 56349.22403012085 43023.87179431295 39047.99175677103 23961.739910713044 40195.14281580191 39977.97181564161 43464.867730972284 46363.280044168736 25701.101992229917 2.275887430672971 2.1924827988759636 1.6740088346141788 1.5193119644665902 0.9323234434833679 1.5639462785663394 1.5554964074197266 1.6911674738348883 1.8039413274257856 1.0 14.649542599071356 -5.33822827272603 2.3633473344770977 1.457661429539927 2.2822991608471845 0.5913725675481922 0.2615790200809155 0.22812879588026766 2.4169386857965383 0.07584521542484877 0.23005003756575856 4.589567138032914e-06 5.33822827272603 0.8246377313072575 T(ph)LSPTPSAEGYQDVR ddPTM_PC-9_AZD4547_30min_R2 1 TLSPTPSAEGYQDVR 15 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4;H0Y7N6;F6XFR5 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 T(0.999)LS(0.001)PTPSAEGYQDVR 206.49 1.6214e-12 140310000.0 13933.0 12751.0 22159.0 32749.0 23653.0 24745.0 20929.0 33906.0 24073.0 17987.0 True False 18363.404175596523 16872.511390604664 21865.157181566614 25199.224017006247 20369.18923049927 23197.69123823671 22791.640455154695 28666.60678236926 25345.449633996453 17357.280604816704 1.0579655070219132 0.9720711311150023 1.2597109927173131 1.451795623446531 1.1735242227314542 1.336481892895093 1.3130882062729305 1.6515609463854712 1.4602200777328567 1.0 14.083253315508056 -5.397160316052076 3.906347084605976 1.3598184488568368 1.0163450423828913 0.3692222445707566 0.1660416176698647 0.22633455311434333 5.92047987922506 0.044685987371628495 0.1002375821974699 4.007187684540745e-06 5.397160316052076 -0.34347340647394553 T(ph)LSPTPSAEGYQDVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TLSPTPSAEGYQDVR 15 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4;H0Y7N6;F6XFR5 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 T(0.537)LS(0.383)PT(0.08)PSAEGYQDVR;T(0.645)LS(0.355)PTPSAEGYQDVR;T(0.988)LS(0.012)PTPSAEGYQDVR;T(1)LSPTPSAEGYQDVR 271.41 5.342e-62 234098500.0 146949.7 160886.0 155078.0 138594.0 193521.0 141501.0 167102.0 151747.0 152888.0 130941.9 True False 171825.38182112685 176857.6988214675 158775.64765659044 130829.02750781065 155601.94925212252 134080.43846172583 151272.88884628617 147763.80203923653 155123.69776432062 154680.62993449016 1.1108396823435345 1.1433732775485184 1.0264740176183313 0.8458009743250912 1.0059562682025704 0.8668211302120449 0.9779691801769411 0.9552831670120362 1.002864404095187 1.0 17.238933019335533 -5.4783586974614735 4.657129779088356 0.9476505660478238 1.12199931929566 0.6374566717225026 0.05289278696275871 0.11721943733603243 5.687035947465917 0.013518656572074822 0.028096795575060052 3.3238491274696178e-06 5.4783586974614735 0.17434875324783627 T(ph)LSPTPSAEGYQDVR ddPTM_PC-9_Lapatinib_30min_R1 2 TLSPTPSAEGYQDVR 15 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4;H0Y7N6;F6XFR5 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 T(0.64)LS(0.36)PTPSAEGYQDVR;T(0.684)LS(0.312)PT(0.003)PSAEGYQDVR 242.01 1.5222999999999998e-32 131137000.0 36876.0 31516.0 40430.0 34408.0 30024.0 33553.0 31560.0 30421.0 36684.0 28326.0 True False 36350.14147776981 31443.026638337265 37106.0014643132 36938.4791017232 28258.04734945515 32118.016405863207 33194.022375734035 31834.47071732049 32552.26162035457 33222.111357977505 1.0941550669699138 0.9464487762240603 1.1169067812844795 1.1118642853159089 0.8505795144976435 0.9667662617761597 0.9991545094187181 0.9582314132384664 0.9798372315833537 1.0 15.019856143063143 -6.238655655819444 24.999788665281983 0.9593929329549075 1.0622485907634616 0.4416572638788009 0.05951540081225786 822.5453993562047 902550.5874739453 0.017819420531422967 0.02298829140466028 5.772239523540273e-07 6.238655655819444 0.1028556578085541 T(ph)LSTHSVPNISGATCSAFASPFGCPYSHR ddPTM_PC-9_AZD4547_30min_R2 1 TLSTHSVPNISGATCSAFASPFGCPYSHR 29 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 T(0.598)LS(0.134)T(0.134)HS(0.134)VPNIS(0.001)GATCSAFASPFGCPYSHR 90.712 2.0798000000000001e-07 7080300.0 5495.8 6654.7 9531.6 14924.0 12169.0 9944.8 7257.8 14995.0 10897.0 11332.0 True False 7243.3500802586195 8805.701635248748 9405.204756163195 11483.502373501522 10479.544402229976 9322.950083896403 7903.7301397783785 12677.867300820704 11472.993173333587 10935.270129192351 0.6623841930454071 0.8052568918020055 0.8600797826708866 1.0501343119860964 0.9583251514065676 0.8525578219607246 0.7227741104153342 1.1593556584374067 1.0491732748975036 1.0 13.416701238639863 -5.034591371181288 1.5033970504137193 0.9603224021127289 0.6272760940667856 0.42042103724571356 0.11412153404801025 0.7808547081510089 2.3261820906256077 0.03596070984415794 0.3376926641401363 9.23439885537054e-06 5.034591371181288 -0.33304630804594326 T(ph)LSTHSVPNISGATCSAFASPFGCPYSHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLSTHSVPNISGATCSAFASPFGCPYSHR 29 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 T(0.448)LS(0.448)T(0.051)HS(0.051)VPNISGATCSAFASPFGCPYSHR;T(0.571)LS(0.143)T(0.143)HS(0.143)VPNIS(0.001)GATCSAFASPFGCPYSHR 90.45700000000001 2.2465999999999997e-07 7725500.0 7499.700000000001 6322.099999999999 16490.5 17553.9 23854.1 21100.1 18754.2 16469.9 16977.0 14897.9 True False 8769.251084173058 6949.71630669667 16883.69606056951 16570.411893511664 19180.06034308964 19993.57361139685 16977.66640735013 16037.582576301518 17225.256507671456 17598.771338288498 0.4982876881350445 0.3948978126431261 0.9593678863158336 0.9415664068241231 1.089852238795832 1.1360778106081835 0.9647074833237324 0.9112899001880658 0.9787760847938055 1.0 14.1031870898874 -5.287547349639642 6.378527852266668 1.0010295697826692 0.4451690904681984 0.9129400671163682 0.0680866732104527 0.044814036462908234 6.981081899345902 0.01978057097729695 0.043751442326459736 5.15765929814274e-06 5.287547349639642 -0.5558604793144708 T(ph)LT(ph)LPAAS(ph)AS(ph)SS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLTLPAASASSSPR 14 0 A0A494C083;Q8IZF5-2;Q8IZF5-3;Q8IZF5 A0A494C083 GPR113 Probable G-protein coupled receptor 113 5 T(1)LT(1)LPAAS(0.892)AS(0.719)S(0.548)S(0.841)PR 48.391000000000005 0.045741000000000004 0.0 4586.9 8228.0 4703.2 6042.6 8596.3 5302.2 6282.9 4159.2 6779.4 4543.5 True False 5363.3715745954405 9044.821463042377 4815.342124985327 5704.052712373519 6911.916724055883 5024.143298010359 5687.738227743132 4050.025407036668 6878.535899635262 5367.200583673789 0.999286591022889 1.6852028021004757 0.8971794606731986 1.0627612334304 1.2878066724543304 0.936082641161771 1.059721569759172 0.7545880471388068 1.2815872618136772 1.0 12.389954090355326 -5.289562670694923 24.994426839217923 1.033576457460479 1.3422450024989256 0.24322964404757308 0.21679239758976712 818.4632078431936 727403.5606595139 0.05327410699090796 0.11093403314007905 5.13378089333579e-06 5.289562670694923 0.30866854503844654 T(ph)LTEPSVDFNHSDDFTPISTVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLTEPSVDFNHSDDFTPISTVQK 23 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 T(0.499)LT(0.452)EPS(0.047)VDFNHS(0.002)DDFTPISTVQK 70.21300000000001 0.0021743 10629000.0 45075.0 70709.0 47082.0 67840.0 67115.0 80021.0 75298.0 55184.0 64314.0 56858.0 True False 52705.30722816919 77728.52222049858 48204.61343947933 64039.144740247546 53964.29753905868 75824.5578910804 68165.22832968879 53735.478472281124 65254.47057986587 67165.9053123196 0.7847032952670103 1.1572615876918966 0.7176946877337425 0.953447205728372 0.8034477803600828 1.128914402902757 1.0148784269745543 0.8000410062577529 0.97154159206869 1.0 16.035441458994462 -6.719169571974351 24.999965414954982 0.9725669192025687 0.8932261019244487 0.11652232566479848 0.134440967337234 410.77514102246306 242946.7407461882 0.0437043561824304 0.04370399124934758 1.9091076944760465e-07 6.719169571974351 -0.07934081727811992 T(ph)LTPPLRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLTPPLRR 8 1 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 T(0.95)LT(0.05)PPLRR 78.939 0.018183 9575300.0 46229.0 37703.0 42021.0 54614.0 49283.0 52539.0 50806.0 48737.0 44814.0 32896.0 True False 54054.65663563028 41445.90466955356 43022.94000552992 51554.154640976994 39626.349930975666 49783.76235037645 45993.28787641335 47457.705391119955 45469.31997024142 38859.7843954073 1.3910179244849028 1.0665500417560705 1.1071327511177504 1.3266711445540083 1.0197264484992603 1.2811126753513384 1.1835703309215768 1.2212549845420348 1.1700867793701726 1.0 15.245990276032677 -8.575770558667449 16.553531928705027 0.9999999970044297 1.192725500371831 0.22751494957231355 0.1091542026412345 448.0135482694591 140216.6415743065 0.0985920865650795 0.025456354316201496 2.6560083823687157e-09 8.575770558667449 0.19272550336740124 T(ph)LTPTPDGK ddPTM_PC-9_Lapatinib_30min_R1 1 TLTPTPDGK 9 0 M0QZR4;Q92888-2;Q92888;Q92888-3;Q92888-4;M0R2C7;M0QYC1;M0QXV6 M0QZR4 ARHGEF1 Rho guanine nucleotide exchange factor 1 1 T(0.625)LT(0.295)PT(0.079)PDGK 83.499 0.021103 0.0 62653.0 97550.0 104250.0 120000.0 105770.0 96260.0 79546.0 76948.0 113120.0 85947.0 True False 61759.55673084695 97324.1289684542 95678.96741663734 128825.20030826483 99548.81655182087 92143.18419301976 83664.5026584327 80523.2849924849 100379.23439359157 100802.82443282117 0.6126768478794546 0.9654900992711241 0.9491695094357345 1.277991971287658 0.9875597942016394 0.9140932777575838 0.8299817304642083 0.7988197299585457 0.9957978356101331 1.0 16.6211765372641 -10.172384545167779 15.738084038695975 0.9999972582978712 0.9328778970577323 0.017106448993928214 0.16087961717745028 0.0 0.0 0.16301526538809286 0.039537009281364804 6.723810342046369e-11 10.172384545167779 -0.06711936124013895 T(ph)LVPPGRPR ddPTM_PC-9_Lapatinib_30min_R1 1 TLVPPGRPR 9 1 Q9HCM7 Q9HCM7 FBRSL1 Fibrosin-1-like protein 1 T(1)LVPPGRPR 63.623999999999995 0.040878 17555000.0 42222.0 28608.0 28573.0 25317.0 23682.0 32728.0 28261.0 32268.0 21173.0 23703.0 True False 41619.906537433504 28541.759933670288 26223.838234969608 27178.896635036213 22289.071320603405 31328.299732694286 29724.216297865005 33767.289080125505 18788.273778425686 27800.031967737803 1.4971172186324748 1.0266808314031173 0.9433024489109443 0.9776570281134057 0.8017642334537629 1.1269159607100838 1.069215184081811 1.2146492895876078 0.6758364091174303 1.0 14.762798921479177 -4.7622049041230285 4.680928526283744 0.9861633646416297 1.5357935858642335 0.5322412795898748 0.1453739483822122 0.1515789407697987 7.8019640561722525 0.03555454916553985 0.27889052459434716 1.72900040848019e-05 4.7622049041230285 0.5496302212226039 T(ph)LYRQSLPPLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLYRQSLPPLAK 12 1 F5H8C5;F5H0S5;F5H7J1;Q8NHQ8-2;Q8NHQ8;F5GYP8 F5H8C5 RASSF8 Ras association domain-containing protein 8 1 T(0.805)LYRQS(0.195)LPPLAK 67.095 0.027174 9903400.0 45052.0 32821.0 40593.0 45807.0 44539.0 43830.0 44687.0 51992.0 45534.0 33829.0 True False 52678.4137824399 36079.251973567574 41560.891069809804 43240.58229829773 35811.902675886726 41531.47764169477 40453.92385413698 50627.26509007758 46199.84860813523 39961.92990978334 1.3182149586209888 0.9028405798973882 1.0400121106171853 1.0820443956514654 0.8961504801378318 1.0392760743901706 1.0123115661697106 1.2668873901829047 1.1560965326858437 1.0 15.28633863745559 -7.731280987002927 24.949779813128018 1.158619117416951 1.0320335804872318 0.10900618329134337 0.1252794569649472 321.2027800129032 265728.45172115247 0.056138703012270606 0.03240636011481882 1.8566028508995615e-08 7.731280987002927 -0.12658553692971908 T(ph)MDKS(ph)TEKT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 TMDKSTEKTK 10 2 Q9H160-2;Q9H160 Q9H160-2 ING2 Inhibitor of growth protein 2 3 T(1)MDKS(0.5)T(0.5)EKT(1)K 64.945 0.035992 0.0 7356.1 5585.6 7111.1 7949.3 7344.0 8507.4 7371.5 6825.3 5497.2 5632.7 True False 7251.2006650564745 5572.6668863782415 6526.452807639807 8533.918040087432 6912.040358859526 8143.558333718019 7753.160200973487 7142.428354982667 4878.047447917708 6606.304689899032 1.097618260953583 0.843537673171325 0.9879127763541822 1.2917839004815657 1.046279377550957 1.2326949355165877 1.1736001539299246 1.081153336131069 0.7383927440367971 1.0 12.689627794471622 -8.175179255330521 8.211700066714986 0.87018209155048 1.0952164044828339 0.31648369000443444 0.13239406935798023 0.36105962552966797 30.85022140978693 0.0944141923767836 0.035419891226005154 6.680681151036854e-09 8.175179255330521 0.22503431293235387 T(ph)MFSNLIHYPRY(ph)S(ph)LY(ph)WSK ddPTM_PC-9_Lapatinib_30min_R1 1 TMFSNLIHYPRYSLYWSK 18 1 Q7Z4T9-2;Q7Z4T9-1;Q7Z4T9-3;Q7Z4T9-8;Q7Z4T9 Q7Z4T9-2 MAATS1 Protein MAATS1 4 T(0.824)MFS(0.189)NLIHY(0.019)PRY(0.964)S(0.967)LY(0.964)WS(0.074)K 57.147 0.030141 0.0 26581.0 31015.0 24102.0 27764.0 24665.0 29394.0 32744.0 32216.0 30710.0 26738.0 True False 26201.950065641606 30943.18667305593 22120.426596410503 29805.857177988917 23214.253193255765 28136.88714076068 34439.32410237754 33712.87297029017 27251.116409363443 31359.627673854488 0.8355312868553921 0.9867204736889859 0.7053791207748619 0.9504531586910071 0.7402592095380718 0.897232819005032 1.098205771463629 1.0750406006381783 0.8689872434959921 1.0 14.936620810294903 -7.06051790551373 6.778222416783074 1.0152455802724343 0.8468200006224686 0.39801981921224683 0.09691293912212126 0.246347156412743 22.950856572630734 0.035703858916252315 0.02781685622932519 8.69925566191698e-08 7.06051790551373 -0.16842557964996563 T(ph)MLCLACGQSMRT(ph)EK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TMLCLACGQSMRTEK 15 1 M0R2J8;H0Y2Q8;H7C298;B6ZDN3 M0R2J8 DCDC1 2 T(1)MLCLACGQS(0.274)MRT(0.726)EK 58.461000000000006 0.043613 0.0 5010.9 5701.8 5517.7 4849.6 5517.7 4179.1 5195.9 4003.8 3828.1 3801.2 True False 5859.1464002137145 6267.83702211656 5649.262893993778 4577.892634615335 4436.546294140868 3959.940639114912 4703.706736941624 3898.704492376761 3884.078720446316 4490.327469717358 1.30483721726926 1.3958529894282043 1.2580959700806338 1.0195008416398388 0.9880228834223809 0.8818823717915095 1.0475197563347638 0.8682450263749169 0.8649878537011906 1.0 12.132604946044966 -5.761395000479313 2.1167812978728033 0.9374475824784088 1.3553755450995895 0.8899400526399558 0.060174786297147634 0.09122851309910805 0.8340661215209538 0.018193805729921762 0.035129598984188895 1.732227781411594e-06 5.761395000479313 0.4179279626211807 T(ph)MQT(ph)LLSLVRQY(ph)NPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TMQTLLSLVRQYNPK 15 1 P00492 P00492 HPRT1 Hypoxanthine-guanine phosphoribosyltransferase 3 T(0.999)MQT(0.709)LLS(0.294)LVRQY(0.997)NPK 70.529 0.019005 0.0 9445.5 18617.0 9677.5 15454.0 10149.0 7577.5 12135.0 8673.0 10478.0 10047.0 True False 11044.436592871267 20465.172724533288 9908.248302123126 14588.162482544003 8160.376305206098 7180.122560573628 10985.484950208169 8445.3429398031 10631.220927571516 11868.441567991766 0.9305717629058583 1.7243352977130726 0.8348398772796655 1.229155689815848 0.6875693205765092 0.6049760214464756 0.9256046707796195 0.7115797715665984 0.8957554255685148 1.0 13.53484288826667 -5.863675160745771 1.5546090092014269 0.7945432804967958 1.2803563589223854 0.3120604143498362 0.2545334926617668 0.4052353962890503 1.9931365541886896 0.07971670894147552 0.15831897771491119 1.3687522284485275e-06 5.863675160745771 0.48581307842558963 T(ph)MQT(ph)LLSLVRQY(ph)NPK ddPTM_PC-9_Lapatinib_30min_R1 1 TMQTLLSLVRQYNPK 15 1 P00492 P00492 HPRT1 Hypoxanthine-guanine phosphoribosyltransferase 3 T(0.999)MQT(0.635)LLS(0.385)LVRQY(0.981)NPK 68.944 0.021247 0.0 17132.0 21764.0 17505.0 19436.0 23040.0 17262.0 27553.0 25986.0 16666.0 21534.0 True False 16887.694538375978 21713.606795176183 16065.806471254076 20865.38827659533 21684.832498382824 16523.74449968738 28979.559522135605 27193.404426556997 14788.899579239696 25256.123207748635 0.6686574340591906 0.8597363346926657 0.6361153031723036 0.8261516664677097 0.8585970348659794 0.6542470657023821 1.1474270727838631 1.0767054073530178 0.58555699374726 1.0 14.624345583275227 -7.24585630589204 24.99405154034343 0.9588145040592341 0.7586870417425946 0.28057432597413257 0.15788341618035245 1090.776357111195 1749523.6620890554 0.05960635255724854 0.046005178347281184 5.67732418775498e-08 7.24585630589204 -0.20012746231663947 T(ph)MSQGEITK ddPTM_PC-9_Lapatinib_30min_R1 1 TMSQGEITK 9 0 H3BV44;H3BRD5;B2RTY4-5;B2RTY4-2;B2RTY4;B2RTY4-4 H3BV44 MYO9A Unconventional myosin-IXa 1 T(0.998)MS(0.002)QGEITK 95.618 0.0060573 0.0 25291.0 25867.0 26687.0 22058.0 24692.0 24453.0 19087.0 20558.0 21292.0 16065.0 True False 24930.345702198636 25807.10655076374 24492.897874799048 23680.218903330908 23239.665106339813 23407.20219272713 20075.23146659174 21513.199730668784 18893.87074530011 18841.81384473306 1.3231393701072751 1.3696720901410306 1.2999225062212183 1.256790832266414 1.2334091238692555 1.2423008944688334 1.065461724227971 1.141779656032557 1.002762839129822 1.0 14.201650235096768 -7.126200768114311 0.5204578737039013 0.9884759160737548 1.3584668431299558 0.9052911871905959 0.03893229766821554 0.2527187827104128 0.14615979660456693 0.03506117444244466 0.03330842999514586 7.478237124070619e-08 7.126200768114311 0.36999092705620096 T(ph)MSVQQPDPPAANPKPER ddPTM_PC-9_AZD4547_30min_R2 1 TMSVQQPDPPAANPKPER 18 1 Q9BZ71;Q9BZ71-3;Q9BZ71-2 Q9BZ71 PITPNM3 Membrane-associated phosphatidylinositol transfer protein 3 1 T(0.768)MS(0.232)VQQPDPPAANPKPER 50.172 0.045773 14431000.0 15291.0 15222.0 21035.0 30657.0 26407.0 24358.0 25649.0 25371.0 27046.0 24364.0 True False 20153.219927441784 20142.21381756599 20756.062155975156 23589.502295928436 22740.84386799958 22834.89040941484 27931.7113113031 21450.49491758066 28475.59634449668 23511.023775824448 0.8571817254578521 0.8567135999529512 0.8828225582127938 1.003337945674007 0.9672417536910147 0.9712418577405867 1.1880261607333447 0.912359033026773 1.2111593529915583 1.0 14.521049741345442 -5.991860927483871 0.7029661010213393 1.0705294452571155 0.8262279119502727 0.47327719448574745 0.08646727957715973 0.7911779627921474 0.7587790676040185 0.04617685288716199 0.12122321055357894 1.0189176200392988e-06 5.991860927483871 -0.2443015333068428 T(ph)MSVQQPDPPAANPKPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TMSVQQPDPPAANPKPER 18 1 Q9BZ71;Q9BZ71-3;Q9BZ71-2 Q9BZ71 PITPNM3 Membrane-associated phosphatidylinositol transfer protein 3 1 T(0.532)MS(0.468)VQQPDPPAANPKPER;T(0.5)MS(0.5)VQQPDPPAANPKPER 66.711 0.008857299999999999 17016900.0 36420.0 36747.0 32820.0 38182.0 46919.0 36749.0 39670.0 42372.0 37518.0 40251.0 True False 42585.18667221128 40394.99930753749 33602.553270543125 36042.78632771419 37725.55876085965 34821.81774708283 35912.17041407151 41259.77989684503 38066.62977291735 47548.18767325932 0.8956216578610169 0.8495591795237923 0.7067052376728314 0.7580265009340057 0.7934173857498288 0.7323479495448006 0.7552794790172033 0.8677466359048878 0.8005905510952983 1.0 15.537102732525303 -9.15573967658456 0.9014962167615673 1.0009836887254413 0.7852740905847061 0.5359573141832071 0.0572934335969023 2.011685473918361 2.1876526193536403 0.06420056928146892 0.019444817136328896 6.986510617841766e-10 9.15573967658456 -0.2157095981407352 T(ph)MSY(ph)RGTFQEFCR ddPTM_PC-9_Lapatinib_30min_R1 1 TMSYRGTFQEFCR 13 1 Q9BR01-2;Q9BR01 Q9BR01-2 SULT4A1 Sulfotransferase 4A1 2 T(0.864)MS(0.408)Y(0.602)RGT(0.126)FQEFCR 65.495 0.036192 0.0 2480.8 2780.8 3857.5 2754.5 4240.5 2914.5 3611.2 4411.7 4271.1 2439.9 True False 2445.4233370769975 2774.3612284518445 3540.3512403806126 2957.0751187426345 3991.082127143768 2789.853629031333 3798.170266262697 4616.683687702669 3790.043741323097 2861.6334640376103 0.8545550531921154 0.9695026506075906 1.23717844541326 1.0333521591442256 1.394686698104434 0.9749164818246849 1.3272735009548302 1.6133036413366433 1.3244336806068622 1.0 11.482623179130655 -4.152729806532831 0.49028129183573094 1.3152691894196544 0.15808400869346462 0.33400605199464184 0.18705068955157292 9.019148317099827 1.0511689977927337 0.11580508202386541 6.847910694841043 7.035098678170117e-05 4.152729806532831 -1.1571851807261897 T(ph)MTSEDLLRALRTVITDSSYKENAMR ddPTM_PC-9_Lapatinib_30min_R1 1 TMTSEDLLRALRTVITDSSYKENAMR 26 3 Q6UWM9 Q6UWM9 UGT2A3 UDP-glucuronosyltransferase 2A3 1 T(0.78)MT(0.11)S(0.11)EDLLRALRTVITDSSYKENAMR 47.43899999999999 0.036209 4346000.0 3703.7 6417.7 23241.0 19232.0 18145.0 14005.0 11025.0 11504.0 19492.0 11338.0 True False 3650.8845588246018 6402.840209952315 21330.214692854384 20646.38543607129 17077.74677444256 13406.038797249554 11595.820554260692 12038.51783741675 17296.60570014043 13297.758193064636 0.27454887551863427 0.4814977169077775 1.6040459138427579 1.5526215123116982 1.2842575813530248 1.0081427713312903 0.8720131909383358 0.9053043123987143 1.3007159138418811 1.0 13.69889542855742 -5.117577561240084 5.818540988862959 1.18411599569081 0.32505096780981274 0.6483696783173303 0.2411642468058612 0.14497502771940293 6.221293213453302 0.06998604158986635 0.19432225114424573 7.628206458228553e-06 5.117577561240084 -0.8590650278809973 T(ph)MY(ph)LEDRTMLT(ph)HSSK ddPTM_PC-9_AZD4547_30min_R2 1 TMYLEDRTMLTHSSK 15 1 F5GX61 F5GX61 RAB6A 3 T(0.996)MY(0.994)LEDRT(0.01)MLT(0.353)HS(0.353)S(0.294)K 48.711000000000006 0.043992 0.0 8134.2 7914.2 10011.0 15552.0 10907.0 12279.0 8976.6 12026.0 12176.0 10669.0 True False 10720.70639812943 10472.310379383842 9878.247598928796 11966.726676004797 9392.751318524308 11511.192188899126 9775.500010021571 10167.658029987992 12819.598502203336 10295.481557390856 1.0413020836731348 1.01717538135611 0.9594740706263963 1.1623280182959677 0.9123178227424921 1.1180819590352762 0.9494941985500421 0.9875845023187766 1.2451674485299313 1.0 13.329723691230317 -8.21358224850363 24.999816261506485 1.1225848323721082 1.0187381733710388 0.17518457278873933 0.09036325406133457 547.9236276933855 286227.58248385496 0.055925315553741514 0.021137591380026913 6.115299778848733e-09 8.21358224850363 -0.10384665900106937 T(ph)NADVMTALSQGYRMPR ddPTM_PC-9_AZD4547_30min_R2 1 TNADVMTALSQGYRMPR 17 1 P07948-2;P07948 P07948-2 LYN Tyrosine-protein kinase Lyn 1 T(0.88)NADVMT(0.108)ALS(0.01)QGY(0.001)RMPR 64.945 0.029642 0.0 2418.4 1235.6 4103.7 3954.8 2830.9 2507.3 947.66 3264.4 2055.9 2653.6 True False 3187.400894155076 1634.9835365250656 4049.2822566900522 3043.081961050914 2437.878399890939 2350.518134638551 1031.9999041393232 2759.9619884494255 2164.5706767969646 2560.6982716929783 1.2447389563190356 0.6384912875518574 1.5813195570335246 1.1883797457476366 0.9520365701965978 0.9179207720886737 0.4030150352142143 1.0778161640358768 0.8453048532601546 1.0 11.322321554162425 -6.515567515648353 2.8233361543106987 0.8268627331136242 1.1525682062546916 0.2271620311922795 0.27197688123650676 0.41894182964279153 6.760636332409626 0.09456686407362244 0.10138934891024882 3.050931692827657e-07 6.515567515648353 0.32570547314106735 T(ph)NEEIHS(ph)ES(ph)Y(ph)NK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TNEEIHSESYNK 12 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 4 T(1)NEEIHS(1)ES(1)Y(1)NK 45.973 0.036409 4559700.0 0.0 2110.4 2295.3 1921.8 1548.3 2201.9 2608.5 2494.3 2396.5 0.0 True False 0.0 2319.9065648522887 2350.028656973726 1814.1277765596653 1244.9217295645483 2086.4284877765854 2361.403996095425 2428.827267929305 2431.5442787674283 0.0 0.0 T(ph)NIPLSPTLTTK ddPTM_PC-9_AZD4547_30min_R2 1 TNIPLSPTLTTK 12 0 H7C066;A0A0D9SG23;A0A1B0GW10;E9PHH0;Q9P267-2;Q9P267 H7C066 MBD5 Methyl-CpG-binding domain protein 5 1 T(0.422)NIPLS(0.076)PT(0.161)LT(0.277)T(0.064)K 90.10799999999999 0.017209000000000002 0.0 22038.0 20205.0 21239.0 31458.0 31267.0 24047.0 24476.0 27409.0 21624.0 23841.0 True False 29045.62558112368 26735.871119689993 20957.356982683927 24205.84412125509 26926.11675770603 22543.33728857864 26654.316583705182 23173.568846161714 22767.000493729036 23006.333846635618 1.2625056114871267 1.162109152110725 0.9109385755413903 1.0521382625591553 1.1703784243591522 0.9798752569121445 1.1585642789236945 1.0072690851415491 0.9895970668555006 1.0 14.489743482073699 -5.024468529065328 6.767620088128243 1.0413260327293294 1.239939847013928 0.489958639935794 0.0757491647656076 0.12464555514358615 24.193224491629145 0.019121183327274843 0.057310623460705326 9.452168846327716e-06 5.024468529065328 0.19861381428459857 T(ph)NSLSRPGALPPR ddPTM_PC-9_AZD4547_30min_R2 1 TNSLSRPGALPPR 13 1 Q5JPT2;Q96B97-2;Q96B97;Q96B97-3;Q5VSN0 Q5JPT2 SH3KBP1 SH3 domain-containing kinase-binding protein 1 1 T(0.724)NS(0.245)LS(0.031)RPGALPPR 73.758 0.014809000000000001 19978000.0 19394.0 18507.0 18105.0 31933.0 35912.0 28477.0 18216.0 26097.0 30851.0 26400.0 True False 25560.888579740127 24489.025825889767 17864.91587040315 24571.340209931932 30926.23868624231 26696.328688271056 19837.18871093209 22064.30829940099 32481.72087643519 25475.7440355346 1.0033421808637566 0.961268326127452 0.701251976997588 0.9644994146455087 1.213948399038126 1.0479116390490475 0.7786696507572997 0.8660908301098016 1.2750057792670695 1.0 14.636836661394943 -5.99349507255227 24.993244390923874 1.0189090470222697 0.8853839332752448 0.1420025753627986 0.1547482242284252 369.75397069696345 1420649.2336113786 0.045951030008450994 0.06796557767934061 1.0150908835942136e-06 5.99349507255227 -0.13352511374702491 T(ph)NSMQQLEQWIK ddPTM_PC-9_AZD4547_30min_R2 1 TNSMQQLEQWIK 12 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;Q9HAU0-3 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 T(0.714)NS(0.286)MQQLEQWIK 111.07 0.004266300000000001 9239200.0 20744.0 21317.0 27062.0 41252.0 47067.0 45348.0 32583.0 37236.0 34150.0 36551.0 True False 27340.160497995705 28207.303373344796 26703.140198003333 31741.988737046675 40532.559485558224 42512.382391253166 35482.823878365205 31482.031798156717 35955.099281393224 35271.36061525854 0.7751376760376019 0.799722576087473 0.7570771224076749 0.8999366109884334 1.1491634793363674 1.2052946540673604 1.0059953248022755 0.8925664122108591 1.0193850947116254 1.0 15.106209609269511 -6.009153664188193 4.37933170581957 1.045729623523258 0.7831013389077669 0.6903420271699203 0.08092250857363498 0.13132413336977597 6.241650589637188 0.02734065248178074 0.038764989060916195 9.791434787978094e-07 6.009153664188193 -0.26262828461549115 T(ph)NSMQQLEQWIK ddPTM_PC-9_Lapatinib_30min_R1 2 TNSMQQLEQWIK 12 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;Q9HAU0-3 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 T(0.739)NS(0.261)MQQLEQWIK;T(0.791)NS(0.209)MQQLEQWIK 159.22 0.00016205 18619100.0 64458.0 41816.0 40817.0 39349.0 49887.0 43977.0 35788.0 37105.0 47954.0 39760.0 True False 63538.81709985051 41719.17762116741 37461.18381817639 42242.856724416015 46952.744741615665 42096.20622539404 37640.92752797114 38829.03375846215 42552.91554199331 46632.463023130185 1.3625447377363404 0.8946380893600723 0.8033284409531457 0.9058680152378638 1.0068682136374958 0.9027231995983974 0.8071829169585326 0.8326610099750157 0.9125170060369022 1.0 15.509047011187642 -4.761586704488491 8.254262682821649 0.8889281885673982 1.3676119516741845 0.8145666561269875 0.06667571282414196 0.03728667684079219 25.12912732120169 0.01724157849135766 0.09990493650367549 1.731463319177529e-05 4.761586704488491 0.4786837631067863 T(ph)NTPQGVLPSSQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TNTPQGVLPSSQLK 14 0 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YF61 Q14004 CDK13 Cyclin-dependent kinase 13 1 T(0.554)NT(0.406)PQGVLPS(0.039)S(0.001)QLK 82.48299999999999 0.022471 14016000.0 78734.0 68024.0 39618.0 74049.0 82587.0 65880.0 93243.0 66392.0 57887.0 74024.0 True False 92062.111132616 74776.97316504573 40562.6433721017 69900.27460009714 66404.67020573992 62425.1368248882 84410.34801913952 64649.28034813878 58733.487863555274 87443.96522633848 1.0528126314300135 0.8551416095038037 0.463870128340018 0.7993721970311897 0.7593968324041482 0.7138873067261764 0.9653078723117509 0.7393223784031486 0.6716699970264444 1.0 16.416071202364726 T(ph)NTPQGVLPSSQLK ddPTM_PC-9_Lapatinib_30min_R1 1 TNTPQGVLPSSQLK 14 0 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YF61 Q14004 CDK13 Cyclin-dependent kinase 13 1 T(0.964)NT(0.036)PQGVLPSSQLK 103.11 0.0031664 17651000.0 89391.0 88716.0 84261.0 82936.0 88340.0 87499.0 88956.0 84841.0 89724.0 79210.0 True False 88116.26794769842 88510.5835526947 77333.38583686619 89035.39010638575 83144.01488312236 83756.8717401312 93561.70641494925 88783.02258729773 79618.33828439355 92901.34295930958 0.9484929403689352 0.9527373957496179 0.8324248431019765 0.9583864696701198 0.8949710761397617 0.9015679329502952 1.0071082229234178 0.9556699586806225 0.8570203158340356 1.0 16.503411831558154 T(ph)NTPVKEDWNVR ddPTM_PC-9_AZD4547_30min_R2 1 TNTPVKEDWNVR 12 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347;A0A494C0Q7 A0A494C1K3 GTF2I General transcription factor II-I 1 T(0.887)NT(0.113)PVKEDWNVR 128.73 0.0020215 39009000.0 21546.0 19211.0 19298.0 21962.0 20996.0 14639.0 23410.0 19165.0 16470.0 19994.0 True False 28397.17981535943 25420.580058419415 19042.095910910793 16899.000209517588 18081.06781734082 13723.621015823297 25493.44464882084 16203.489617887879 17340.570575828584 19294.01614569997 1.4718127942319708 1.317536995224546 0.9869430898737316 0.8758674234489974 0.9371334449396385 0.711288977483408 1.3213135334968884 0.8398194287558491 0.8987538128339989 1.0 14.235865858364685 -5.176008993250668 2.6224243228198243 0.9381488105841943 1.4584882608726155 0.6048203594817401 0.1477595318680813 0.19576695388025728 2.5123089605017874 0.03930179295481293 0.14839794745274956 6.667929613054325e-06 5.176008993250668 0.5203394502884212 T(ph)NY(ph)QIMES(ph)S(ph)ELIPRPGHQFAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TNYQIMESSELIPRPGHQFAK 21 1 C9JG08;Q68DN1 C9JG08 C2orf16 Uncharacterized protein C2orf16 4 T(1)NY(1)QIMES(1)S(1)ELIPRPGHQFAK 46.494 0.042235 0.0 0.0 543.13 542.32 659.74 910.3 399.61 0.0 614.34 880.1 0.0 True False 0.0 597.0483569788779 555.2509655600534 622.7769067059393 731.9332496432271 378.6537481267998 0.0 598.2142259470351 892.9697975143819 0.0 0.0 T(ph)PAAPASPAAVPSEGSGGSTTGWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPAAPASPAAVPSEGSGGSTTGWR 24 0 P07199 P07199 CENPB Major centromere autoantigen B 1 T(0.898)PAAPAS(0.102)PAAVPSEGSGGSTTGWR 105.19 3.8157e-06 62161000.0 27000.0 29252.0 30722.0 28627.0 40694.0 35570.0 34959.0 30825.0 30882.0 26794.0 True False 31570.566725692035 32155.945240266836 31454.528993833803 27023.12199998622 32720.302824323287 33704.64658259373 31647.43043875792 30015.87641178723 31333.590826995955 31651.54009881269 0.9974417240719452 1.0159361958337398 0.9937756234178862 0.8537695769502195 1.033766531491802 1.0648659268197207 0.9998701592389521 0.9483227772829034 0.9899546982287708 1.0 14.949988079483076 -5.5198569717906825 24.996738088049096 0.9833084589908295 1.0062307118403144 0.02729511295398057 0.05288711582421932 548.8106631096886 4539879.502835968 0.015380614294523623 0.02732374104208413 3.0209464588541983e-06 5.5198569717906825 0.022922252849484903 T(ph)PAEIPR ddPTM_PC-9_Lapatinib_30min_R1 1 TPAEIPR 7 0 Q05GC8 Q05GC8 BCAR2 1 T(1)PAEIPR 94.85 0.010431999999999999 0.0 5043.0 6343.1 9368.6 6302.3 8212.8 9108.5 7556.5 8740.0 8361.2 6257.3 True False 4971.085895227064 6328.412941668905 8598.349871841814 6765.792165856488 7729.739250986052 8718.950687950557 7947.738595761541 9146.09230693867 7419.473608660689 7338.865967671841 0.6773643117512985 0.8623148275967917 1.1716183276432732 0.9219124856156553 1.0532607197128319 1.1880514954705639 1.0829654923215415 1.246254168863115 1.010983664416809 1.0 12.841341433668562 -5.0117053724576754 3.0086233602654726 1.0898439935418731 0.6808346991047702 0.6650010432029265 0.09329777871127769 0.15643770387718664 2.688474268374923 0.0244237447848126 0.1184388304570689 9.734073642405825e-06 5.0117053724576754 -0.4090092944371029 T(ph)PAIPTAVNLADSR ddPTM_PC-9_AZD4547_30min_R2 1 TPAIPTAVNLADSR 14 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(1)PAIPTAVNLADSR 75.02 0.043945 5312400.0 2895.7 1992.7 2128.5 7105.8 6976.7 2057.2 4592.5 2808.8 2453.7 4965.8 True False 3816.472365698332 2636.801305627629 2100.274699262807 5467.667593515619 6008.105631608011 1928.5629587916978 5001.22360314864 2374.764499802949 2583.397572672168 4791.948853471884 0.7964342864246567 0.5502565628840554 0.43829238656024194 1.1410112588230488 1.2537916858722296 0.4024590031661976 1.0436721584632798 0.49557384112778546 0.5391120923171859 1.0 12.226396794367195 -12.000948134780351 2.1431074373626453 3.7058771418499625 0.7443196250661279 0.06577166045787963 0.2934996391029601 15559964.987653581 774594.3006740495 205807921.1010633 0.07525411371865898 9.97819220351333e-13 12.000948134780351 -2.9615575167838344 T(ph)PAPEPEPCEASELPAKR ddPTM_PC-9_AZD4547_30min_R2 3 TPAPEPEPCEASELPAKR 18 1 H0Y5D5;A0A494C0L7;Q9BTG3;Q5SYW2;F5H2X7;Q9ULV3-5;Q9ULV3-3;Q9ULV3-4;Q9ULV3-2;Q9ULV3 H0Y5D5 CIZ1 Cip1-interacting zinc finger protein 1 T(1)PAPEPEPCEASELPAKR;T(1)PAPEPEPCEASELPAKR;T(1)PAPEPEPCEASELPAKR 168.62 7.0586e-25 0.0 29971.300000000003 30384.8 46329.0 39368.0 37354.0 37129.0 34084.0 49249.0 38171.0 38381.0 True False 39501.549958232696 40206.092392851104 45714.64718916914 30292.31582953686 32168.041876974152 34807.31776053711 37117.40997054289 41638.69867943441 40188.64113235905 37037.29287226721 1.066534481730728 1.085556996066433 1.2342869482072585 0.817886877801999 0.8685311312550315 0.9397910878794314 1.0021631467113967 1.124237098619393 1.085085815287853 1.0 15.17669103261617 -5.74936407241895 24.999044696721295 0.9769919795457481 1.1244691803109803 0.3501394630978236 0.09482672617322765 296.2793324078375 613370.3266976494 0.029005466991385072 0.04975395253969514 1.7808852116762338e-06 5.74936407241895 0.14747720076523219 T(ph)PAPEPEPCEASELPAKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPAPEPEPCEASELPAKR 18 1 H0Y5D5;A0A494C0L7;Q9BTG3;Q5SYW2;F5H2X7;Q9ULV3-5;Q9ULV3-3;Q9ULV3-4;Q9ULV3-2;Q9ULV3 H0Y5D5 CIZ1 Cip1-interacting zinc finger protein 1 T(1)PAPEPEPCEASELPAKR 74.141 0.0331 0.0 8942.3 13713.0 13706.0 14133.0 20553.0 12579.0 13580.0 10703.0 10099.0 10174.0 True False 10456.054771524296 15074.336013940223 14032.803020294452 13341.17382980421 16525.787190945004 11919.335095936076 12293.60408931412 10422.057590765888 10246.678769569073 12018.465662660314 0.8699991384099711 1.2542645989141583 1.1676035372711844 1.1100563253472 1.3750330245805258 0.9917518117947266 1.0228929743926152 0.867170392901796 0.8525779460687787 1.0 13.552965105701427 -7.200707553476044 2.242558179317015 0.9099351344366572 1.1570677964573752 0.37008035913582726 0.13190890223392096 0.3128187146808651 3.0800810594092263 0.060559452782429656 0.04135561232762882 6.299302243784112e-08 7.200707553476044 0.24713266202071804 T(ph)PAPEPEPCEASELPAKR ddPTM_PC-9_Lapatinib_30min_R1 3 TPAPEPEPCEASELPAKR 18 1 H0Y5D5;A0A494C0L7;Q9BTG3;Q5SYW2;F5H2X7;Q9ULV3-5;Q9ULV3-3;Q9ULV3-4;Q9ULV3-2;Q9ULV3 H0Y5D5 CIZ1 Cip1-interacting zinc finger protein 1 T(1)PAPEPEPCEASELPAKR;T(1)PAPEPEPCEASELPAKR;T(1)PAPEPEPCEASELPAKR 118.54 8.358e-05 6383800.0 26534.0 37237.0 41011.0 36678.0 41011.0 45404.0 34455.0 43274.0 45925.0 34330.0 True False 26155.620294260356 37150.780014334465 37639.23388703806 39375.4224742212 38598.813610728255 43462.17676189353 36238.91131039023 45284.66801950386 40752.44288831052 40263.894758150396 0.6496048246541232 0.9226822252910404 0.9348135373669723 0.9779337719496363 0.958645800228129 1.079433001277049 0.9000349203191425 1.1246966616496317 1.012133653067957 1.0 15.297199111582612 -4.241287916478428 1.0367986819043384 1.0103091347284394 4.9662777086336104e-15 0.749426732453408 0.06086406666503433 2.3436590711640726 0.9411098300336203 0.01856963682267735 3.4328680447979005 5.73735976576498e-05 4.241287916478428 -1.0103091347284345 T(ph)PAQPQRR ddPTM_PC-9_AZD4547_30min_R2 1 TPAQPQRR 8 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 T(1)PAQPQRR 68.626 0.036575 779100.0 841.27 503.36 770.41 2063.7 2133.6 1194.3 1042.1 892.83 969.74 909.97 True False 1108.7763604969566 666.0612762587059 760.1938600230486 1587.945848847165 1837.3864686168029 1119.6202322015 1134.844881184801 754.8636386923475 1020.998476636552 878.1122272733113 1.2626818373089927 0.7585149774385218 0.8657137851087447 1.8083632131829077 2.092427837296153 1.2750309099761796 1.2923688407217473 0.859643693877636 1.162719803830687 1.0 9.778261525188853 -7.645550594827912 6.215374859409912 1.010436101245917 1.3450070803460905 0.14005204535532423 0.3748842981419335 0.4988068029496745 25.081113155559503 0.20626995494254163 0.11723754787579807 2.2617750301254104e-08 7.645550594827912 0.3345709791001734 T(ph)PAQPQRR ddPTM_PC-9_Lapatinib_30min_R1 1 TPAQPQRR 8 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 T(1)PAQPQRR 73.84100000000001 0.024494 939470.0 1328.3 1116.1 2195.3 1238.2 951.53 1005.5 1500.1 874.58 2203.4 927.66 True False 1309.358198419613 1113.515739022979 2014.810908103061 1329.2613585141153 895.562876179957 962.497108934982 1577.767837954329 915.2161796112607 1955.229889169372 1088.0047949707482 1.2034489227180438 1.0234474555352642 1.8518400998014264 1.2217421877721168 0.823124015923142 0.884644179312518 1.4501478718177419 0.8411876343209195 1.7970783752124362 1.0 10.087469199398571 -5.9947484733512235 24.894053764520464 1.1186086989061463 1.3611031966060303 0.07931587780312133 0.3439490321825814 348.76618109505455 1653242.5828101125 0.09560504738448121 0.14128153388742762 1.0121654918349217e-06 5.9947484733512235 0.24249449769988396 T(ph)PAQSGAWDPNNPNTPSR ddPTM_PC-9_Lapatinib_30min_R1 1 TPAQSGAWDPNNPNTPSR 18 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 T(1)PAQSGAWDPNNPNTPSR 124.25 0.00010178 0.0 6162.5 8620.1 6508.7 5018.6 7861.6 5585.3 7356.8 6252.1 7777.9 6234.5 True False 6074.621619935903 8600.140688067366 5973.579810308562 5387.684585558823 7399.196144500286 5346.42973897022 7737.699106901144 6542.5953904131875 6901.870997081994 7312.125018050932 0.8307600875176381 1.176147927837229 0.8169416955484217 0.7368151627958524 1.011907773217007 0.7311731850552147 1.0582011505273263 0.8947597824520148 0.9438940089295282 1.0 12.836075021548801 -9.887988689972001 7.051123753164973 0.9999955947408851 0.9125808529107747 0.03756148594898423 0.13471474355833124 172573252.4437578 0.0 0.12615113755727222 0.03153778438931807 1.294229545727636e-10 9.887988689972001 -0.08741474183011033 T(ph)PASGLQTPTSTPAPGSATR ddPTM_PC-9_Lapatinib_30min_R1 2 TPASGLQTPTSTPAPGSATR 20 0 Q96DF8 Q96DF8 DGCR14 Protein DGCR14 1 T(0.752)PAS(0.019)GLQT(0.188)PT(0.027)S(0.008)T(0.004)PAPGS(0.002)ATR;T(0.975)PAS(0.024)GLQTPTSTPAPGSATR 194.1 1.3774999999999998e-48 0.0 13709.4 10037.1 13969.2 9625.5 11409.0 16974.8 7642.299999999999 7155.5 10800.400000000001 12649.0 True False 13513.901442003955 10013.859711627592 12820.706298671377 10333.391379726714 10737.945050957027 16248.827374191485 8037.980899938912 7487.970652437029 9583.945218745983 14835.362796266938 0.9109249047421 0.6749993140813116 0.8641990408146598 0.696537828001546 0.7238073782502337 1.0952767112834088 0.5418122232886364 0.5047379531777441 0.6460202794068249 1.0 13.856752587660196 T(ph)PASINATPANINLADLTR ddPTM_PC-9_Lapatinib_30min_R1 2 TPASINATPANINLADLTR 19 0 Q7KZ85;Q7KZ85-2 Q7KZ85 SUPT6H Transcription elongation factor SPT6 1 T(0.997)PAS(0.003)INATPANINLADLTR;T(0.924)PAS(0.076)INATPANINLADLTR 126.26 7.4573e-05 4996900.0 14905.3 14630.400000000001 15023.5 9320.6 13496.2 13723.8 9244.099999999999 9752.4 10837.8 8728.0 True False 14692.747688702748 14596.524207689097 13788.325822387074 10006.068016610127 12702.380050550113 13136.865065740336 9722.714266271312 10205.532106886574 9617.132836906521 10236.623170671028 1.4353119621320996 1.4259120380155863 1.3469603786815205 0.9774774209993912 1.2408760036164788 1.2833201776322878 0.9497970281965524 0.9969627617168196 0.9394829404740218 1.0 13.3214522610616 -4.75868887093321 0.3272669464928276 0.943163567210567 1.9019694869498596 0.6744067130773674 0.11145360550314774 4.484646206626631 0.3842625564148365 0.12286658949019509 1.7302927173570686 1.743055152921916e-05 4.75868887093321 0.9588059197392925 T(ph)PASKSPSEGQTATTSPR ddPTM_PC-9_Lapatinib_30min_R1 1 TPASKSPSEGQTATTSPR 18 1 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 T(0.928)PAS(0.033)KS(0.018)PS(0.018)EGQT(0.002)AT(0.001)T(0.001)SPR 52.365 0.040083 3457900.0 9100.0 11967.0 13780.0 10037.0 11789.0 11205.0 11006.0 10082.0 12166.0 7631.6 True False 8970.232331264386 11939.291146750285 12647.061592338252 10775.154462450466 11095.594198065763 10725.788270130752 11575.83682722841 10550.446526150536 10795.736966340468 8950.711891532206 1.0021808812493056 1.333892911696266 1.4129671187721913 1.2038321189451162 1.2396325937563375 1.1983167819620975 1.2932867203758056 1.178727083834723 1.206131657142684 1.0 13.127786715814329 -9.277943988032632 0.6762552966488707 0.9927148933950973 1.2493894233110305 0.31532171616591564 0.10225652618037454 3.3873914293381433 2.1000289286077916 0.1610528956864103 0.03870162766106978 5.272978638669209e-10 9.277943988032632 0.2566745299159332 T(ph)PATTPEAR ddPTM_PC-9_Lapatinib_30min_R1 2 TPATTPEAR 9 0 A0A0C4DG98;Q8NI27;Q8NI27-2;H0Y7U4;H7C477 A0A0C4DG98 THOC2 THO complex subunit 2 1 T(0.731)PAT(0.135)T(0.135)PEAR;T(0.666)PAT(0.167)T(0.167)PEAR 104.01 0.0066786 16545700.0 57807.0 48441.0 60584.0 44032.0 58686.0 61911.0 52662.0 64322.0 70553.0 48855.0 True False 56982.66157949452 48328.83784070619 55603.01738100296 47270.26016644605 55234.20486111522 59263.2108515899 55388.580682855005 67310.63493900553 62606.57818397323 57299.52165480446 0.9944701095897652 0.843442256496637 0.970392348403501 0.8249677973093956 0.9639557759987676 1.0342706036642941 0.9666499664087644 1.1747154774609125 1.0926195607904132 1.0 15.806235474742415 -6.998630132099186 1.310429032334634 1.0856540455820778 0.9080484034918535 0.481259068618875 0.07091099007300912 0.3425338172509629 1.2004444866299617 0.03730494616625959 0.027180073573995107 1.003159217249088e-07 6.998630132099186 -0.17760564209022434 T(ph)PCEEILVK ddPTM_PC-9_AZD4547_30min_R2 2 TPCEEILVK 9 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 T(1)PCEEILVK;T(1)PCEEILVK 118.23 0.004425899999999999 13913800.0 61929.0 63165.0 77692.0 64474.0 69198.0 83430.0 71287.0 84984.0 73246.0 60944.0 True False 81621.13379677855 83581.85099110226 76661.75331694906 49610.515413370216 59591.05214442513 78213.10891113733 77631.40489878214 71851.6755380424 77117.63402532741 58810.369109909865 1.3878697758933969 1.4212094271147546 1.303541441368562 0.8435674892747881 1.0132745814442392 1.3299203881030905 1.3200292069872561 1.2217518207335143 1.3112931476625043 1.0 15.843782924825105 -1.5612158131568448 0.018281898386280818 4.996219527355984e-06 2.7393823963340447 0.12263099796856325 0.1723799538137627 11125.870152904927 15.839430544003264 905.0297764984651 1547.6698374205434 0.02746528986345997 1.5612158131568448 2.7393774001145172 T(ph)PCEEILVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPCEEILVK 9 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 T(1)PCEEILVK 91.069 0.019772 7596400.0 12091.0 25077.0 14876.0 15278.0 19301.0 16444.0 14716.0 12880.0 16316.0 11731.0 True False 14137.767491864535 27566.478831880624 15230.70025754417 14422.02319194431 15519.107603387813 15581.647691992446 13321.993945386352 12541.913647488056 16554.59063316061 13857.737437455085 1.0202074873819285 1.9892481695729898 1.0990755400212882 1.040719905181928 1.1198875482690507 1.1244005568959567 0.96133975733869 0.9050477182219816 1.1946099215602393 1.0 13.758404106416938 -5.4858125764608685 24.92319357367135 1.0495571453794723 1.5145865917142276 0.37875942562206966 0.23076000770395433 476.5905371839272 320457.3916087163 0.05516310999373914 0.11477592226667958 3.2672880439210865e-06 5.4858125764608685 0.4650294463347553 T(ph)PCEEILVK ddPTM_PC-9_Lapatinib_30min_R1 2 TPCEEILVK 9 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 T(1)PCEEILVK;T(1)PCEEILVK 123.51 0.0036466999999999997 14107700.0 49582.0 81714.0 63759.0 56159.0 70790.0 73564.0 73317.0 74679.0 68802.0 57734.0 True False 48874.951587774776 81524.79625349336 58516.98113685742 60289.12020093212 66626.27137849486 70417.83920605965 77112.99551716376 78148.85896909314 61052.79424282075 67713.2449742807 0.7217930791285928 1.2039711918171794 0.864188109122281 0.8903593414232555 0.9839474005979377 1.0399418789161003 1.13881701499394 1.1541148116410043 0.9016374014568382 1.0 16.047150437718187 -6.674168495413189 3.0903153369682443 1.0638257513585831 0.9366149044553163 0.16402684422191927 0.13026810716872675 0.46219616453859913 8.86717039102575 0.045042027552409616 0.04402176243317397 2.1175394234427454e-07 6.674168495413189 -0.1272108469032669 T(ph)PDIAQR ddPTM_PC-9_AZD4547_30min_R2 1 TPDIAQR 7 0 Q9UEW8-2;Q9UEW8 Q9UEW8-2 STK39 STE20/SPS1-related proline-alanine-rich protein kinase 1 T(1)PDIAQR 91.265 0.037587999999999996 7170000.0 10615.0 14429.0 17580.0 26733.0 26861.0 25183.0 15463.0 31732.0 18177.0 15117.0 True False 13990.349194283865 19092.89207552619 17346.877713432055 20570.1198707328 23131.813804610032 23608.303028996386 16839.177044199765 26828.548528819112 19137.79911091901 14587.758431256696 0.9590472216970098 1.3088297400522138 1.1891393592221466 1.410094632953196 1.585700360587702 1.6183639961031762 1.1543361595650659 1.83911384708253 1.3119081455251616 1.0 13.832470593952674 -4.440840084393419 0.8480966501159712 1.4520145846608048 0.4548412647643609 0.22556277886059217 0.23474368324182826 5.137009810390183 1.9305568894496152 0.0798166480867818 5.48116273371473 3.6237640783750726e-05 4.440840084393419 -0.9971733198964439 T(ph)PDSTFSETFK ddPTM_PC-9_AZD4547_30min_R2 2 TPDSTFSETFK 11 0 B7Z1S6;Q9NZI5-3;Q9NZI5 B7Z1S6 GRHL1 Grainyhead-like protein 1 homolog 1 T(1)PDSTFSETFK;T(0.999)PDS(0.001)TFSETFK 108.56 0.0053047 16032800.0 38870.0 44879.0 50855.0 44116.0 50358.0 46253.0 47853.0 54364.0 46371.0 44378.0 True False 51229.85145377427 59385.25909332184 50180.629471933265 33945.73778540558 43366.660942353265 43360.79259818802 52111.82429645552 45963.29296044127 48822.07639172721 42824.33972761194 1.196278840015429 1.3867174478590238 1.1717782408581583 0.7926739326588687 1.0126638546721516 1.012526821755764 1.216873969988036 1.0732983451185687 1.1400543873475788 1.0 15.386143382331735 -5.525076400970778 24.99975418392462 1.0393880352458478 1.2884356079321395 0.4628745303726739 0.11171035891015847 58.4447658324933 664844.6485252578 0.03166116287284501 0.05529447227607608 2.984857477387311e-06 5.525076400970778 0.24904757268629174 T(ph)PDSTFSETFK ddPTM_PC-9_Lapatinib_30min_R1 2 TPDSTFSETFK 11 0 B7Z1S6;Q9NZI5-3;Q9NZI5 B7Z1S6 GRHL1 Grainyhead-like protein 1 homolog 1 T(0.995)PDS(0.004)T(0.001)FSETFK;T(1)PDSTFSETFK 106.26 0.006006 13824200.0 22617.0 37221.0 34914.0 26601.0 40816.0 37034.0 34551.0 36534.0 40463.0 33695.0 True False 22294.47743255016 37134.81706135143 32043.505691937426 28557.32627833464 38415.2831273435 35450.14215047054 36339.88172065861 38231.503013924186 35905.630845720385 39519.13585423468 0.5641438495715789 0.939666727489241 0.8108351814707963 0.7226202107168438 0.9720678931097403 0.8970373816175405 0.9195515270044703 0.9674174849100979 0.9085631573058021 1.0 15.270263780104615 -3.2812229820104175 0.33269382589345226 0.9658322157072295 2.165239363205063e-20 0.5254215190252844 0.08851821374697715 16.691955152480084 0.6748659564278991 0.08242816405931029 7.91149983192068 0.0005233316707705394 3.2812229820104175 -0.9658322157072295 T(ph)PDTIRR ddPTM_PC-9_AZD4547_30min_R2 1 TPDTIRR 7 1 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 1 T(1)PDTIRR 80.455 0.021547 10941000.0 11511.0 9616.8 14519.0 22278.0 18807.0 13434.0 15542.0 12346.0 10494.0 11970.0 True False 15171.258556326105 12725.242533226161 14326.468573453933 17142.15129166891 16195.972682450416 12593.969856313284 16925.207891156486 10438.209382856456 11048.691416074395 11550.933943384443 1.3134226747972295 1.1016635187767028 1.2402865987870286 1.4840489414699423 1.4021353391711084 1.0902988380022913 1.465267481756317 0.903668000701772 0.9565193143886259 1.0 13.49572188409263 -7.775052672600833 24.995011227574484 0.9475700925124296 1.2926847498552259 0.6053976319634125 0.12797100822818988 168.35274400815587 309103.47548579535 0.07125196396881497 0.034520087746293414 1.678600419837354e-08 7.775052672600833 0.3451146573427962 T(ph)PDTIRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPDTIRR 7 1 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 1 T(0.999)PDT(0.001)IRR;T(1)PDTIRR 86.67 0.01178 0.0 22595.7 18411.9 22870.3 25238.6 26226.0 26610.0 27559.0 18619.0 22796.0 25892.0 True False 26420.7057245822 20239.711751991963 23415.614688095735 23824.563066645213 21087.20356491625 25214.524755772258 24948.41201011841 18130.27097846118 23129.34837420501 30586.014639040764 0.863816552642924 0.6617309247657746 0.765566059012064 0.7789364959053847 0.6894393994698482 0.824380850311495 0.8156803789099618 0.5927634310133116 0.7562066731205354 1.0 14.900584515374415 -11.162659994447077 2.7753916383779456 1.0253822077319774 0.7462958765491867 0.48281105924941226 0.07759745951502607 35368136.07858015 33448460.656981725 6441580.929720833 0.018882053494383398 6.876065508191704e-12 11.162659994447077 -0.2790863311827907 T(ph)PDTIRR ddPTM_PC-9_Lapatinib_30min_R1 1 TPDTIRR 7 1 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 1 T(1)PDTIRR 78.516 0.023954 9768000.0 17489.0 13758.0 14095.0 8888.2 10112.0 12677.0 9500.5 10023.0 14367.0 8814.3 True False 17239.603652910202 13726.144196288997 12936.163508273425 9541.867878166018 9517.232040956907 12134.834261530348 9992.389403696488 10488.705170760439 12748.837168782968 10337.840010683514 1.6676214407549492 1.3277574601758086 1.2513410436710866 0.9230040190508938 0.9206209451027914 1.1738268583175744 0.9665838698770707 1.0145934895414337 1.2332205911107 1.0 13.335647159844195 -4.9115091280715975 1.320981590973923 1.036164886926432 1.8300689865803332 0.7706790074421751 0.10663599781919478 0.49457606301115326 0.9082945934646968 0.03231601003846074 0.49907101602623577 1.2260011341171764e-05 4.9115091280715975 0.7939040996539013 T(ph)PDTSTYCYETAEK ddPTM_PC-9_AZD4547_30min_R2 4 TPDTSTYCYETAEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.989)PDT(0.009)S(0.001)T(0.001)YCYETAEK;T(0.985)PDT(0.013)S(0.002)TYCYETAEK;T(0.619)PDT(0.163)S(0.183)T(0.031)Y(0.003)CYETAEK;T(1)PDTSTYCYETAEK 249.39 5.9049e-35 281019000.0 102669.0 101450.0 109800.0 106305.8 108129.0 120652.0 116441.0 145809.0 130145.0 109305.0 True False 135315.6063521367 134241.72853712187 108343.98025795454 81798.64021823763 93117.1547924009 113107.61136697249 126804.02342389371 123277.56940749336 137024.19900371655 105478.26521985243 1.2828766767266522 1.272695642626627 1.0271687729422643 0.7755023278752411 0.8828089331798662 1.0723309786259558 1.202181540998908 1.1687485488175327 1.2990752049070178 1.0 16.6865862232273 -9.29882630486494 13.774481984789697 1.0000065649646295 1.0985765477991363 0.03390606932175966 0.16639180505788867 0.0 0.0 0.18226970519521835 0.04420689687471044 5.025435405326184e-10 9.29882630486494 0.0985699828345068 T(ph)PDTSTYCYETAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TPDTSTYCYETAEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(1)PDTSTYCYETAEK;T(1)PDTSTYCYETAEK;T(1)PDTSTYCYETAEK;T(0.996)PDT(0.004)STYCYETAEK;T(0.999)PDTSTYCYETAEK 209.22 1.1642e-10 234401200.0 119999.0 156821.0 141456.0 127045.0 134413.0 105177.0 127439.0 90593.0 100119.1 96113.0 True False 140312.4606117158 172389.15248611686 144828.8475148676 119927.08053544752 108075.73754179392 99661.33296647343 115367.05534153894 88215.02974121772 101583.15243077165 113537.52606991041 1.235824537213527 1.5183451538301858 1.2756033403941676 1.0562770273997582 0.9518944201342434 0.8777832001122453 1.0161138729630415 0.7769680456741638 0.8947099337731043 1.0 16.792809685848198 -5.835691263311275 2.021006077480792 0.9103378138813867 1.3854185720932002 0.8164693933322998 0.09040614967845298 0.11984835604646903 0.9993582824005068 0.027154340675389837 0.04971107994706079 1.45985168909416e-06 5.835691263311275 0.4750807582118135 T(ph)PDTSTYCYETAEK ddPTM_PC-9_Lapatinib_30min_R1 4 TPDTSTYCYETAEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(1)PDTSTYCYETAEK;T(0.989)PDT(0.007)S(0.004)TYCYETAEK;T(1)PDTSTYCYETAEK;T(0.999)PDT(0.001)STYCYETAEK 241.41 3.2436e-27 285995000.0 81617.0 100417.0 104681.0 91756.0 98592.0 85615.0 94004.0 79392.0 96703.0 80155.0 True False 80453.12661327547 100184.49060610226 96074.53226034535 98504.04232904286 92793.01239933 81953.44602831277 98871.06715489538 83080.84215474543 85811.28981226555 94009.68495017596 0.8557961518104724 1.065682654496703 1.0219641977447722 1.047807386879861 0.9870580084223154 0.8717553523527618 1.0517115040572245 0.8837476925784542 0.9127920156071636 1.0 16.52052177155079 -6.5380279003070685 24.87768951644102 0.9419051148459269 1.0060164745522775 0.10937697957114301 0.07260186974499726 433.93851845628836 712601.6485996199 0.023194793502905462 0.023202692907671203 2.897157460125192e-07 6.5380279003070685 0.06411135970635062 T(ph)PDVFSSSPLHLQPPPLGK ddPTM_PC-9_AZD4547_30min_R2 1 TPDVFSSSPLHLQPPPLGK 19 0 G5E9C8;Q07889 G5E9C8 SOS1 Son of sevenless homolog 1 1 T(0.486)PDVFS(0.122)S(0.196)S(0.196)PLHLQPPPLGK 115.38 0.00015517 10596000.0 49019.0 50915.0 99626.0 120640.0 103470.0 96373.0 77781.0 114900.0 79553.0 87818.0 True False 64606.02234146028 67372.27805290844 98304.89414552794 92828.31186941988 89104.97652220675 90346.78107506927 84703.35831823727 97144.84513933322 83758.00916933155 84743.51854971879 0.7623712520687479 0.7950139338783923 1.16002846976259 1.0954030875524452 1.05146656696735 1.066120248736935 0.9995260967190315 1.1463395289911005 0.9883706813541256 1.0 16.37081541017298 -5.246397979092782 23.000431904772572 1.0671649749737744 0.7786923500415908 0.8031335512789435 0.056360118052626126 106.80982256416259 163324.86652390292 0.013722289278126841 0.035899672933986056 5.670247566968482e-06 5.246397979092782 -0.2884726249321836 T(ph)PDYFL ddPTM_PC-9_AZD4547_30min_R2 2 TPDYFL 6 0 H0YBN9;P67775-2;P67775;P62714 H0YBN9 PPP2CB;PPP2CA Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform;Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform 1 T(1)PDYFL;T(1)PDYFL 68.915 0.018815000000000002 2681000.0 11731.3 12293.5 14476.9 15917.0 13773.0 15369.0 13092.9 18117.7 13753.9 13501.4 True False 15461.60937380145 16267.133462504773 14284.926846961573 12247.581565198583 11860.856689285356 14407.974000422726 14258.142735691843 15318.025768328072 14480.903074856635 13028.72009550633 1.1867327918982797 1.2485595932109546 1.0964182776394524 0.9400448758909813 0.9103623842050473 1.1058625785806933 1.0943625030834414 1.1757122461792187 1.1114601410349716 1.0 13.669407744149211 -5.390396633979098 4.759404224141878 1.0519226350539073 1.2158605758452963 0.41995652039149867 0.0781827019318019 0.23703426912448072 8.041514700929081 0.02357981498262456 0.05106603393306241 4.070083939667346e-06 5.390396633979098 0.16393794079138901 T(ph)PEAPAHSEKPR ddPTM_PC-9_Lapatinib_30min_R1 1 TPEAPAHSEKPR 12 1 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;Q9NUQ6-2 B8ZZZ7 SPATS2L SPATS2-like protein 1 T(1)PEAPAHSEKPR 97.163 0.0025308 1556000.0 10024.0 14839.0 10936.0 8733.7 9792.0 8418.4 11801.0 8826.9 9926.7 7171.2 True False 9881.055921823532 14804.641207205443 10036.884294180789 9376.005432769127 9216.053811812702 8058.36465624888 12411.998037263535 9237.029998182712 8808.650513214858 8410.732364976635 1.174815163893398 1.7602083343959274 1.1933424889342168 1.1147668271804738 1.095749265568065 0.958104990928607 1.4757333248349076 1.0982432441492118 1.0473107609386318 1.0 13.038015713361023 -5.493526789415223 21.149175341652867 1.1271408598382835 1.4698286626530375 0.35956602868308396 0.18599849834521004 103.91650681332828 74873.75211448489 0.04657619383793727 0.09646447185289729 3.2097648040568448e-06 5.493526789415223 0.342687802814754 T(ph)PEASAIGLHQDPELGDAALR ddPTM_PC-9_AZD4547_30min_R2 1 TPEASAIGLHQDPELGDAALR 21 0 G5E953;Q13615-3;Q13615-2;Q13615 G5E953 MTMR3 Myotubularin-related protein 3 1 T(0.991)PEAS(0.009)AIGLHQDPELGDAALR 79.36 0.024314 0.0 2951.5 4284.9 5033.8 5382.8 6515.8 5676.0 5697.8 7227.3 3943.3 5171.5 True False 3890.0156049862326 5669.910129213545 4967.048522973509 4141.878623430983 5611.1936408949 5321.078822721022 6204.893161898814 6110.486851832042 4151.734787593496 4990.447359082091 0.7794923631258853 1.1361526775540278 0.995311274836714 0.8299613893117614 1.1243869010426724 1.0662528707045105 1.243354095421237 1.2244366911739077 0.8319363954491522 1.0 12.28495343365156 -6.29066156338538 24.734555068381678 1.1002572423827401 0.9538726203579175 0.19343341424714577 0.14155883506106237 1024.0992889617626 866826.236000267 0.04370185929941503 0.04956126793290725 5.12080733908906e-07 6.29066156338538 -0.1463846220248226 T(ph)PEDGDYSYEIIEK ddPTM_PC-9_AZD4547_30min_R2 2 TPEDGDYSYEIIEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(1)PEDGDYSYEIIEK;T(0.997)PEDGDY(0.001)S(0.002)YEIIEK 180.85 9.755e-05 6634900.0 10907.6 9609.3 11244.7 13376.4 12850.5 16824.4 13756.7 13890.0 13623.6 15120.3 True False 14375.989907825793 12715.31830489666 11095.587930843534 10292.677643319876 11066.429890776259 15772.36760834876 14981.01964974085 11743.619660446795 14343.715682869362 14590.942899261132 0.9852680534137226 0.8714528178669351 0.7604435167384146 0.7054155248487117 0.7584451510215046 1.0809697301431735 1.0267341701748056 0.8048568033969538 0.9830561178877419 1.0 13.832785495987832 -6.747859808487719 24.99970544690335 0.9699026043033663 0.8100214914362254 0.4104363920623608 0.09717532749967829 266.8850271003475 491328.8719654682 0.034980882800351575 0.0347997827418127 1.78706435128517e-07 6.747859808487719 -0.1598811128671409 T(ph)PEDGDYSYEIIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPEDGDYSYEIIEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.999)PEDGDY(0.001)SYEIIEK;T(1)PEDGDYSYEIIEK 91.845 0.010708 7540200.0 32788.0 39147.0 35782.0 33217.0 36647.0 36213.0 41289.0 29900.0 31622.0 25795.0 True False 38338.36080748115 43033.25544649001 36635.17858399067 31355.959180966995 29466.28342269068 34313.92653065693 37377.807013526544 29115.156681668705 32084.411927053494 30471.429306892343 1.2581740233238545 1.4122493242138892 1.2022796244646177 1.029028171444343 0.9670134973296344 1.1261016404929667 1.2266509272366835 0.9554903509263064 1.0529342619250326 1.0 14.895169552878833 -5.548363908186364 3.8309734713616987 1.0570181680667143 1.3332701955825021 0.6573318298572783 0.0828338234880846 0.13189523194339142 4.220355836065332 0.023713642463382235 0.04638180642086973 2.829020482454931e-06 5.548363908186364 0.2762520275157878 T(ph)PEDGDYSYEIIEK ddPTM_PC-9_Lapatinib_30min_R1 2 TPEDGDYSYEIIEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.964)PEDGDY(0.011)S(0.014)Y(0.011)EIIEK;T(1)PEDGDYSYEIIEK 119.62 0.00024105 5567000.0 12062.4 14193.7 13464.2 13204.8 16386.4 14954.2 16476.800000000003 13076.5 15095.7 11567.400000000001 True False 11890.387964026757 14160.835359708326 12357.22544931501 14175.925041921486 15422.584168901934 14314.643725942822 17329.88808239842 13684.081928110247 13395.463301231774 13566.809677408362 0.876432134507407 1.0437852152735025 0.9108423972286154 1.0448974651371008 1.1367878326312657 1.0551223217776662 1.277373862718542 1.0086440551235245 0.9873701791172086 1.0 13.72779388116751 -5.929265486990601 5.280033531728959 1.0872824971048605 0.9547982898852798 0.3052382327548574 0.08916185857874052 0.2511144473752114 12.950887787890334 0.025504387389997933 0.03824226023570866 1.176886315456091e-06 5.929265486990601 -0.13248420721958065 T(ph)PEEGGYSYDISEK ddPTM_PC-9_AZD4547_30min_R2 6 TPEEGGYSYDISEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(1)PEEGGYSYDISEK;T(1)PEEGGYSYDISEK;T(1)PEEGGYSYDISEK;T(1)PEEGGYSYDISEK;T(1)PEEGGYSYDISEK;T(1)PEEGGYSYDISEK 203.11 3.0849999999999997e-10 319218100.0 297493.0 342343.8 321840.0 331202.3 334696.3 370973.5 383338.9 459676.7 382029.4 304110.9 True False 392089.5857611947 452999.73845211254 317572.19131347997 254848.7267595256 288229.4960236741 347776.468400404 417455.31947414996 388644.22833472287 402222.6941555223 293464.0699551537 1.336073563694229 1.543629305357002 1.0821501636026871 0.8684154308855283 0.9821628115077954 1.1850734178584457 1.4225091321671652 1.324333259584774 1.3706028619346442 1.0 18.16282435334064 -7.0265586891989855 22.709757725787377 1.3060180706374822 1.1549362951057809 0.06351949531910439 0.20318945303529937 617.1152542358167 527678.8273876238 0.08537131178168637 0.06642893457528222 9.406787010671142e-08 7.0265586891989855 -0.15108177553170132 T(ph)PEEGGYSYDISEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 TPEEGGYSYDISEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(1)PEEGGYSYDISEK;T(1)PEEGGYSYDISEK;T(1)PEEGGYSYDISEK;T(1)PEEGGYSYDISEK;T(1)PEEGGYSYDISEK;T(1)PEEGGYSYDISEK 190.86 4.4328e-06 270416900.0 312061.0 468486.0 480942.0 323348.0 384913.0 324955.0 447957.0 258076.0 314034.0 320634.0 True False 364886.76381430397 514994.1939638881 492409.4812626908 305231.8598683594 309492.0607710908 307913.78774941666 405523.2700321708 251301.77845412513 318626.1531560411 378762.4060626518 0.9633658408906278 1.3596761075562023 1.300048456185064 0.8058663029452571 0.8171139897128469 0.8129470687185467 1.070653432181156 0.6634813129066375 0.8412296153365775 1.0 18.530933618129836 -5.764531075730066 24.99853423829056 0.8499195921199856 1.2228947683216482 0.5568701930801309 0.14229664700993944 53.030294374209525 428792.5981653787 0.03886954870530853 0.060539930248805086 1.719764279940311e-06 5.764531075730066 0.37297517620166265 T(ph)PEEGGYSYDISEK ddPTM_PC-9_Lapatinib_30min_R1 6 TPEEGGYSYDISEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.999)PEEGGYSYDISEK;T(1)PEEGGYSYDISEK;T(1)PEEGGYSYDISEK;T(1)PEEGGYSYDISEK;T(1)PEEGGYSYDISEK;T(1)PEEGGYSYDISEK 204.17 2.7522e-10 330263300.0 345178.1 420066.0 350843.0 347811.3 452353.0 382628.7 418031.4 423545.0 406731.0 352907.0 True False 340255.79699608876 419093.36298577825 321998.04283314483 373390.50326648395 425746.48590021534 366264.5624520644 439675.02044865105 443224.44692704175 360920.671712693 413906.50473098183 0.8220595547712828 1.012531473160026 0.7779487375836898 0.9021131559871686 1.0286054484138365 0.8848968505341991 1.0622568513012798 1.0708322818340705 0.8719859861764508 1.0 18.658945395798902 -6.130604266521751 5.686028941684874 0.9882841215613521 0.8782905687087282 0.28907953340435055 0.08344030220523165 0.30810307898719375 12.967043765015081 0.02419476256031774 0.03154217240077557 7.402795179284764e-07 6.130604266521751 -0.10999355285262391 T(ph)PEFLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPEFLR 6 0 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 1 T(1)PEFLR 122.74 0.037904 20912000.0 25310.0 29153.0 34654.0 23825.0 32145.0 13927.0 26174.0 21565.0 19188.0 24507.0 True False 29594.483104713538 32047.11717453507 35480.282786026844 22490.162491692172 25846.41800481327 13196.643602917708 23694.60923665007 20998.941600006205 19468.588199870417 28949.925102694746 1.0222645827141983 1.1069844588838686 1.2255742514071042 0.7768642720805768 0.8927974049372379 0.4558437908251902 0.8184687577808105 0.7253539180331613 0.6724918330810542 1.0 14.821271995324906 -5.811612644212612 7.6167528790882955 0.7453123372580355 1.116683100149694 0.5639767262900577 0.14254130519929575 0.15035990357146092 19.3653969534785 0.03918501620553579 0.058775566475939296 1.5430761393056894e-06 5.811612644212612 0.3713707628916585 T(ph)PEGISEEQR ddPTM_PC-9_AZD4547_30min_R2 1 TPEGISEEQR 10 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 T(1)PEGISEEQR 98.898 0.011203 14196000.0 2724.7 8162.0 7518.9 4267.7 4066.9 2436.0 2457.0 4414.1 2843.7 3321.0 True False 3591.09792271929 10800.20688339073 7419.194473238015 3283.847700307722 3502.2811348039345 2283.676534909867 2675.668240160306 3732.0022709271543 2994.012176471389 3204.7328008337277 1.12056079114772 3.370080301415769 2.3150742774273954 1.0246868941627245 1.0928465343172442 0.7125949889849652 0.8349114907377667 1.1645283718992905 0.9342470535117565 1.0 11.645988359764473 -5.760976874559965 5.778379688967736 0.957291021351836 2.3906232742253497 0.5653047251362511 0.520714677702095 0.10069732360542141 11.621043839911671 0.13802414446559017 0.22450310714408112 1.7338963223163107e-06 5.760976874559965 1.4333322528735137 T(ph)PEGISEEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPEGISEEQR 10 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 T(0.999)PEGIS(0.001)EEQR 91.961 0.018918 8665100.0 2823.3 2865.9 3357.9 3526.4 2341.0 4448.8 3746.3 3519.0 3608.2 3818.5 True False 3301.228927283197 3150.4076119267324 3437.965070906667 3328.827240743053 1882.2978550091104 4215.497096335199 3391.42334313678 3426.629978688702 3660.963098956245 4510.763822770634 0.7318558578966993 0.6984199873252656 0.7621691593675537 0.7379741816538727 0.4172902703322986 0.9345417454700445 0.7518512332693303 0.7596562607403313 0.8116060256747342 1.0 12.13915603522001 -8.896410862510422 0.5207091711872242 1.0108995412428723 0.6984272487171785 0.35511794341536984 0.11728743602801461 1.8216079151395679 0.9767997897636622 0.1652389493682933 0.059909404072671826 1.2693726522005733e-09 8.896410862510422 -0.31247229252569375 T(ph)PEGISEEQR ddPTM_PC-9_Lapatinib_30min_R1 2 TPEGISEEQR 10 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 T(0.66)PEGIS(0.34)EEQR;T(1)PEGISEEQR 124.12 0.0010347000000000002 23033800.0 9595.5 13107.0 9176.0 10315.1 7642.8 13965.5 14239.0 11898.1 5102.6 5383.4 True False 9458.666410400812 13076.651546791683 8421.584700384308 11073.706864164871 7193.265530322936 13368.22812017056 14976.225748037916 12450.929162149532 4527.891455239923 6313.913517070401 1.498067147234153 2.071084995294508 1.3338137555440968 1.7538578623583954 1.1392721029318986 2.117265002763816 2.3719402724709395 1.9719828484325916 0.7171291534162196 1.0 12.624318784567318 -8.263137176610533 24.996627748701485 0.8585644721448109 1.7853028743219457 0.5091789646466067 0.36270685028527666 130.68837889865856 1924034.4676399052 0.3110545478329261 0.09650427567422243 5.455855047882872e-09 8.263137176610533 0.9267384021771348 T(ph)PELPEPSVK ddPTM_PC-9_AZD4547_30min_R2 4 TPELPEPSVK 10 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 T(1)PELPEPSVK;T(1)PELPEPSVK;T(1)PELPEPSVK;T(1)PELPEPSVK 134.75 0.00027409 100113000.0 438271.0 384573.0 542696.0 645457.0 640974.0 581227.0 504508.0 581295.0 461801.0 481870.0 True False 577632.0613968896 508878.70151509735 535499.4964487334 496656.86086124217 551985.8241166037 544882.7838079052 549408.2346385005 491469.21458023106 486210.8580745732 464999.87796981365 1.2422198128714084 1.0943630861514595 1.1516121225380114 1.0680795509659975 1.187066599945295 1.171791240433997 1.1815233953118722 1.0569233194769476 1.0456150229487513 1.0 18.826870812050238 -7.875395024861772 4.768514791159528 1.0315953774908027 1.1522321868588492 0.5878290302746214 0.0472505136127127 0.15865813111147248 5.848902916616023 0.02703611621504521 0.012499987391471332 1.3323090413943837e-08 7.875395024861772 0.12063680936804655 T(ph)PELPEPSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TPELPEPSVK 10 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 T(1)PELPEPSVK;T(1)PELPEPSVK;T(1)PELPEPSVK;T(1)PELPEPSVK;T(1)PELPEPSVK 130.01 0.00055607 78081900.0 605456.0 675799.0 674019.0 732893.0 756004.0 701707.0 697913.0 638543.0 590866.0 536289.0 True False 707947.7424989124 742887.8585200023 690090.1691912925 691831.3812811638 607870.4432201218 664908.2496354255 631801.628187443 621781.9228422332 599506.29744135 633513.9504386127 1.1174935327134714 1.1726464081898507 1.0893054031620129 1.0920539015789235 0.9595217955330949 1.0495558135303524 0.9972971041127284 0.9814810272319072 0.9463190148003566 1.0 19.27301686334829 -5.970384091519487 1.484718185006537 0.9890137909600788 1.1430908080246087 0.7821701635538845 0.03330774051066171 0.17804115295558914 0.7956599756535877 0.011347500861401079 0.020518777525399857 1.0705720688445512e-06 5.970384091519487 0.15407701706452992 T(ph)PELPEPSVK ddPTM_PC-9_Lapatinib_30min_R1 4 TPELPEPSVK 10 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 T(1)PELPEPSVK;T(1)PELPEPSVK;T(1)PELPEPSVK;T(1)PELPEPSVK 118.9 0.0020397 99384000.0 679370.0 570120.0 567450.0 528280.0 534540.0 503360.0 490700.0 508393.0 555360.0 415096.0 True False 669682.0592187993 568799.9221680682 520796.45142034366 567131.4734904182 503099.4081460748 481832.46618947043 516106.04498645966 532014.7947598939 492809.5085999373 486844.7905193465 1.3755555615669819 1.168339341910787 1.0697381620634758 1.164912277043008 1.0333876790781484 0.9897044716766321 1.060103866852305 1.0927811185827045 1.0122517857780258 1.0 18.893102378904885 -1.5228787453127965 0.7022845068614024 1.0410983413196588 43.20140810819878 0.8366522167423232 0.04456179377384195 113.26787070188603 0.5956157045590416 0.017958638230155845 7501.3409153691255 0.029999999997757813 1.5228787453127965 42.16030976687912 T(ph)PENHENLFLQPPK ddPTM_PC-9_AZD4547_30min_R2 1 TPENHENLFLQPPK 14 0 Q7LBC6;Q7LBC6-2 Q7LBC6 KDM3B Lysine-specific demethylase 3B 1 T(1)PENHENLFLQPPK 81.494 0.021713999999999997 16561000.0 16750.0 22804.0 33552.0 37699.0 36103.0 48814.0 31879.0 47083.0 33185.0 39649.0 True False 22076.151578356545 30174.947043474906 33107.078557512636 29008.077993743886 31090.72163314231 45761.65286333755 34716.16924219391 39807.40420970601 34939.09135147979 38260.90057821635 0.5769898576544612 0.7886627493722628 0.8652979427348342 0.7581650602928957 0.8125977476558316 1.196042230364847 0.9073536879045493 1.0404199485144934 0.913180056492768 1.0 15.223583211530277 -6.578493951046568 10.505391621260427 1.0073998746616915 0.7619798697947086 0.6125127829273782 0.1006198583781628 0.33781569682353624 61.97045781868863 0.03258743610100318 0.03258843824532295 2.6394050843507965e-07 6.578493951046568 -0.2454200048669829 T(ph)PENHENLFLQPPK ddPTM_PC-9_Lapatinib_30min_R1 1 TPENHENLFLQPPK 14 0 Q7LBC6;Q7LBC6-2 Q7LBC6 KDM3B Lysine-specific demethylase 3B 1 T(1)PENHENLFLQPPK 91.40100000000001 0.0095493 14800000.0 123270.0 121580.0 119930.0 94706.0 169180.0 175620.0 170370.0 139000.0 172310.0 142870.0 True False 121512.1471950508 121298.48897985311 110069.81834318781 101670.99516995483 159229.16502067752 168109.14199021534 179190.92497318765 145458.44744444804 152902.6332952594 167564.88913769164 0.7251647276488912 0.7238896501771296 0.6568787704251163 0.6067559599935617 0.9502537544714127 1.0032480124883232 1.0693822906178312 0.8680723521078556 0.9124980422934309 1.0 17.35436035871568 -6.274033266807124 22.450488793844706 0.9675533901213154 0.6799168553292572 0.8485663534894946 0.05982232831244649 76.9082382075427 137099.97417196273 0.020049123933982387 0.022934355921522445 5.32067501519185e-07 6.274033266807124 -0.2876365347920582 T(ph)PENLITEIR ddPTM_PC-9_AZD4547_30min_R2 2 TPENLITEIR 10 0 Q5VY60;Q7Z4H7-3;Q7Z4H7;Q5SYF9 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 T(1)PENLITEIR;T(1)PENLITEIR 152.38 0.00041488 11615300.0 2771.6 2594.11 4483.200000000001 3672.1000000000004 740.1 4318.0 3244.5 10211.2 3392.9 2468.02 True False 3652.9111471386873 3432.605326914079 4423.749838729158 2825.5540783794527 637.3498900559131 4047.9947773977015 3533.25421457066 8633.293670032708 3572.2417672573656 2381.615371006824 1.5337955874858271 1.4412929009032012 1.857457712350515 1.186402352276117 0.2676124355825242 1.699684519455557 1.4835536659628556 3.6249739463106496 1.4999238797099326 1.0 11.2177247225716 -7.550681435615009 24.970944273488747 2.2483223654304103 1.3289467932274146 0.13621571538217303 0.7504454052651252 308.5404043241099 277111.4431088663 0.34172278264570066 0.19729859779999154 2.8139641770686176e-08 7.550681435615009 -0.9193755722029957 T(ph)PENLITEIR ddPTM_PC-9_Lapatinib_30min_R1 2 TPENLITEIR 10 0 Q5VY60;Q7Z4H7-3;Q7Z4H7;Q5SYF9 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 T(1)PENLITEIR;T(1)PENLITEIR 113.99 0.0030451000000000002 10088600.0 2219.62 1593.46 2320.71 1203.59 2474.78 2549.3 3711.9 4414.2 4064.6000000000004 1389.9 True False 2187.9678117715425 1589.7704412718908 2129.9101819996595 1292.1060236585392 2329.218306004683 2440.2723817085525 3904.0840195338096 4619.299846829365 3606.8019458644976 1630.142363074665 1.342194314639333 0.9752341128497346 1.3065792474605507 0.7926338539055299 1.4288434916883384 1.496968876451916 2.394934398349227 2.833678794848784 2.21256868575674 1.0 10.67078224760506 -7.042072395621574 2.5650950064241838 2.259659685619531 1.1420240718341503 0.45260925492751514 0.47484197984396587 0.219413160110794 2.8700757071130805 0.1912408576547255 0.14852270732568523 9.076692117600376e-08 7.042072395621574 -1.1176356137853807 T(ph)PEPAPR ddPTM_PC-9_AZD4547_30min_R2 1 TPEPAPR 7 0 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;K7ENL0;K7ER34;K7EJ51 Q9UHD8 SEPT9 Septin-9 1 T(1)PEPAPR 87.476 0.043806 8252400.0 16679.0 19265.0 25829.0 22605.0 26434.0 32636.0 24160.0 31628.0 31782.0 28144.0 True False 21982.57505524829 25492.034502391863 25486.4905836312 17393.766493768562 22764.09538405351 30595.26576080393 26310.193195878324 26740.619339136872 33461.931635761044 27158.68712636689 0.8094122868666432 0.9386327985509666 0.9384286679633992 0.6404494596088889 0.8381883585953274 1.1265369941649592 0.9687579179899013 0.9846064802291514 1.2320894408505731 1.0 14.729126119733726 -6.749101224065812 24.845947865007304 1.0555835481274318 0.834046915890162 0.5401156801833604 0.10573194846212718 178.26535478188993 358981.02958663297 0.03604183199033923 0.03578851054466942 1.7819633843175794e-07 6.749101224065812 -0.22153663223726983 T(ph)PESFLGPNAALVDLDSLVSRPGPTPPGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPESFLGPNAALVDLDSLVSRPGPTPPGAK 30 1 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 T(0.934)PES(0.066)FLGPNAALVDLDSLVSRPGPTPPGAK 123.02 1.1325000000000001e-17 3087100.0 1130.7 2547.1 2793.4 3908.1 4242.2 2503.9 3427.6 3956.2 2578.8 2185.4 True False 1322.105177657037 2799.959254802532 2860.0052500284955 3689.1418272311503 3410.9713628875056 2372.5910761359683 3102.912914324968 3852.353941940392 2616.510071389712 2581.5957203831185 0.5121271185950184 1.0845847135147124 1.107843969312151 1.4290160919091033 1.3212647262915762 0.9190405211021448 1.2019360312018506 1.492237499281525 1.0135243294412541 1.0 11.334047375986948 -4.620449008147593 1.9912006067650636 1.2082563278765814 0.06268211419053253 0.557670394960567 0.17807516299615606 0.9588436507860387 2.8426108700863666 0.04770329078083813 2.335327947281236 2.3963540965417157e-05 4.620449008147593 -1.145574213686049 T(ph)PESFLGPNAALVDLDSLVSRPGPTPPGAK ddPTM_PC-9_Lapatinib_30min_R1 1 TPESFLGPNAALVDLDSLVSRPGPTPPGAK 30 1 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 T(0.748)PES(0.252)FLGPNAALVDLDSLVSRPGPTPPGAK 48.84 0.010894 3212800.0 841.73 927.9 832.27 775.1 910.29 634.11 597.27 1050.5 1159.4 622.14 True False 829.7267758456229 925.7515045600057 763.8439732551058 832.1034396578021 856.7485318989975 606.9905934826068 628.1937181354456 1099.3100650387953 1028.8161629767505 729.6760700505582 1.137116605438537 1.2687157254531614 1.046826125464386 1.1403737546170958 1.1741491424264943 0.831863094318756 0.8609213648625189 1.5065727247470588 1.409962865995407 1.0 9.511112330686231 -7.767490141130091 24.99992116169715 1.3437008089759186 1.0708394330411541 0.272736421413737 0.17602724938488198 181.67606315160964 750614.4715172418 0.09597019583562214 0.04798044756180655 1.7080864946979045e-08 7.767490141130091 -0.27286137593476445 T(ph)PGPPGLTTTPAPPDK ddPTM_PC-9_AZD4547_30min_R2 2 TPGPPGLTTTPAPPDK 16 0 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 T(1)PGPPGLTTTPAPPDK;T(1)PGPPGLTTTPAPPDK 151.11 4.5256e-05 33259000.0 144414.0 164989.0 170887.0 155421.0 153836.0 212416.0 123261.0 188702.0 132956.0 148743.0 True False 190334.64800219567 218318.46771425527 168620.9267244176 119591.08968051332 132478.5268026505 199133.5939406461 134230.9902118026 159542.44184057813 139983.78272494642 143535.55284384542 1.3260453193033208 1.5210062133649032 1.174767668243581 0.8331809597766927 0.9229666391209429 1.3873468279826577 0.9351759027802303 1.1115186354850137 0.9752551193866023 1.0 17.131048601990322 -5.46114924556802 5.084109527067959 1.0330238629974389 1.415095347099998 0.5349275355515131 0.14759221057149563 0.16244054022639998 8.448913524759497 0.03969522034095354 0.08330336021996917 3.458205159690539e-06 5.46114924556802 0.3820714841025592 T(ph)PGPPGLTTTPAPPDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPGPPGLTTTPAPPDK 16 0 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 T(0.935)PGPPGLT(0.002)T(0.013)T(0.05)PAPPDK;T(1)PGPPGLTTTPAPPDK 109.14 0.0017517 16722200.0 40733.0 45884.0 44456.0 37008.0 89366.0 64658.0 86216.0 58419.0 75629.0 78963.0 True False 47628.29238657827 50439.06028320811 45515.99964031884 34934.56174155485 71855.37381919885 61267.2206560963 78048.99633021413 56885.56315004693 76734.93104898882 93278.36682923611 0.5106038410146156 0.5407369575364293 0.48795879674485065 0.3745194403490066 0.7703326747856108 0.6568213267311773 0.8367320203311207 0.6098473320634659 0.8226444529144339 1.0 16.509254908782665 -6.274608813746166 24.578144425394466 0.7596267256067728 0.48358234930526645 0.6522098874904321 0.10803883683318821 400.58593134723793 747612.7198832948 0.03175835413769582 0.03623165436626125 5.313628483188112e-07 6.274608813746166 -0.27604437630150636 T(ph)PGPPGLTTTPAPPDK ddPTM_PC-9_Lapatinib_30min_R1 2 TPGPPGLTTTPAPPDK 16 0 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 T(1)PGPPGLTTTPAPPDK;T(0.999)PGPPGLTTT(0.001)PAPPDK 160.93 0.00014012 28594000.0 35357.0 59141.0 55500.0 45200.0 81594.0 128597.0 124678.0 131093.0 130130.0 128909.0 True False 34852.80269632029 59004.06264811221 50937.004236195426 48524.15878277986 76794.80133997613 123097.20608424845 131133.21678586066 137184.05935852503 115473.38907035065 151190.74888955455 0.23052205873905948 0.39026238762276994 0.33690556208174555 0.32094661306444716 0.5079332029506318 0.8141847764387453 0.8673362474158653 0.9073574961834373 0.7637596209984013 1.0 17.206010340586538 -6.655654919624296 2.15477919226058 0.8785812598757221 0.3238144294331329 0.9412783106837065 0.06559648099612796 0.06669346333161426 0.6336124183458024 0.023891901623072642 0.023589581252563226 2.2097598598381342e-07 6.655654919624296 -0.5547668304425892 down T(ph)PGT(ph)PGTPSYPR ddPTM_PC-9_Lapatinib_30min_R1 2 TPGTPGTPSYPR 12 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 2 T(1)PGT(0.68)PGT(0.287)PS(0.033)YPR;T(1)PGT(0.769)PGT(0.207)PS(0.024)YPR 114.87 0.0038189 3913300.0 36119.0 43859.0 42282.0 38139.3 38311.0 34548.0 31374.0 34202.0 35054.0 24521.1 True False 35603.93643658661 43757.44718018892 38805.737173239926 40944.19135097509 36057.62230232398 33070.46257532151 32998.392205839 35791.14978053962 31105.84938501553 28759.539462688077 1.2379870158483688 1.521493320049814 1.3493170578612894 1.4236734007543856 1.2537621594777015 1.1498954153360599 1.1473894513731804 1.2444966243974172 1.081583709828577 1.0 14.811752953093844 -6.519470125082846 2.594460540965939 1.1400191794986998 1.3910544052832314 0.6520584438838433 0.08838549721874879 0.17560613593609792 2.3802946024613845 0.029373964063441674 0.031497292148889466 3.023638558059756e-07 6.519470125082846 0.25103522578453163 T(ph)PHTPGTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPHTPGTPK 9 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 T(0.999)PHT(0.001)PGTPK 89.14200000000001 0.023409 2767600.0 21495.0 16830.0 18351.0 25708.0 27548.0 21181.0 19898.0 24100.0 19414.0 15049.0 True False 25133.67895439817 18500.77117440486 18788.557436555046 24267.66410646054 22150.167154972663 20070.23107298052 18013.117390955253 23467.400536060723 19697.893022320422 17777.264572181542 1.4138102547974782 1.0406984212495485 1.056886865820516 1.365095513312852 1.2459828712699694 1.1289830891298704 1.0132671040483237 1.3200793879606931 1.1080384691548295 1.0 14.117745730052754 -6.777195582162921 23.62545052772956 1.127778111953448 1.2127834548121028 0.13465935113083927 0.13617666886603558 356.6560547455437 534777.8827441488 0.04869671279395752 0.04311665870948894 1.6703382171536032e-07 6.777195582162921 0.0850053428586548 T(ph)PIQAGGYGEFAAFK ddPTM_PC-9_Lapatinib_30min_R1 1 TPIQAGGYGEFAAFK 15 0 H7C560;A0A2R8Y8E0 H7C560 BRAF 1 T(1)PIQAGGYGEFAAFK 78.903 0.027923000000000003 1481000.0 3931.3 1304.6 1485.0 1405.5 2793.4 4877.1 4341.5 3946.8 4495.0 3560.2 True False 3875.238941087873 1301.579278854385 1362.90903226577 1508.8651586105539 2629.0977040357056 4668.517802075389 4566.281626877353 4130.182736501776 3988.7257655515696 4175.57582633169 0.9280729418563408 0.31171252373061153 0.32640025925792066 0.36135498943534117 0.6296371598514138 1.118053652058034 1.0935693223631155 0.9891289030021537 0.9552516662248542 1.0 12.02775944859834 -6.62784624513492 4.171509569918992 1.0332486909697525 0.4617485127666469 0.7021671280926968 0.17080413390340257 0.12096009134409658 3.8241274043257807 0.058874634660623454 0.05875701567283795 2.3558831982223531e-07 6.62784624513492 -0.5715001782031055 T(ph)PISPLK ddPTM_PC-9_AZD4547_30min_R2 1 TPISPLK 7 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 T(0.994)PIS(0.006)PLK 89.355 0.040724 248350000.0 343300.0 290250.0 334380.0 348760.0 359230.0 341030.0 351690.0 372570.0 322300.0 330760.0 True False 452462.2589164067 384067.6363518944 329945.90271998954 268358.7702882865 309357.1152611608 319705.340188962 382989.728686193 314997.8673068872 339336.12001150876 319180.1930755083 1.4175762429261014 1.2032940786555504 1.0337292535001832 0.8407751361463742 0.969224036993976 1.0016452998176157 1.1999169653850963 0.9868966625769547 1.063149053021696 1.0 18.28401160144083 -4.95658633569838 2.265785602640048 1.0098564340416394 1.4465587898142371 0.7003977232517644 0.08408152076441622 0.25089534408387715 2.0189963820623418 0.02458107722460058 0.19132868578944848 1.1051307527534677e-05 4.95658633569838 0.43670235577259775 T(ph)PISPLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TPISPLK 7 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 T(0.638)PIS(0.362)PLK;T(0.993)PIS(0.007)PLK;T(0.704)PIS(0.296)PLK 91.853 0.036623 324610000.0 937100.0 965590.0 793010.0 1070520.0 1081400.0 854640.0 1039500.0 967420.0 850900.0 694130.0 True False 1095732.5214313315 1061447.3938380012 811918.3659071731 1010542.2350726691 869507.4328948517 809821.1738922648 941031.0346717265 942026.2500662162 863342.8027553561 819970.2742699442 1.3363076148180013 1.2944949678609445 0.9901802435826835 1.2324132554346554 1.060413359092819 0.98762259962812 1.1476404257575898 1.1488541470664213 1.0528952449209557 1.0 19.645212084239887 -5.161642624864104 6.03814230651811 1.0873616266565989 1.3237689136899167 0.6089087161647071 0.07609096245165364 0.15089539548809328 7.5325276851692315 0.019047053672818354 0.05221522218251555 6.892192123544957e-06 5.161642624864104 0.23640728703331781 T(ph)PKDSPGIPPSAGAHQLFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPKDSPGIPPSAGAHQLFR 19 1 E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2;Q5SVM6 E9PGT3 RPS6KA1 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 T(0.909)PKDS(0.09)PGIPPS(0.001)AGAHQLFR;T(0.836)PKDS(0.156)PGIPPS(0.008)AGAHQLFR 99.39200000000001 0.00036218 41761000.0 53821.0 71634.0 130709.0 150442.0 210376.0 220929.0 174117.0 174654.0 160448.0 125428.0 True False 62931.832286795274 78745.35010738682 133825.59827664297 142013.22247954446 169154.33299675255 209343.0943167231 157623.37726208463 170069.51756120985 162794.24846220633 148167.1035124983 0.424735523573806 0.5314631132054521 0.9032072241687199 0.9584666171702902 1.1416456756373317 1.4128851098116015 1.0638216819078783 1.1478223811459205 1.0987205972375251 1.0 17.17686564632111 -5.363162929752158 1.238202894427047 1.1558042234407082 0.35329666238714935 0.8486987314865172 0.108474022311168 0.2354850743384399 0.577057606972639 0.03618657046196761 0.18577705569601768 4.3334827311514015e-06 5.363162929752158 -0.8025075610535588 down T(ph)PKDSPGIPPSANAHQLFR ddPTM_PC-9_AZD4547_30min_R2 1 TPKDSPGIPPSANAHQLFR 19 1 B4DG22;B1AXG1;B7ZB17;P51812 B4DG22 RPS6KA3 Ribosomal protein S6 kinase alpha-3 1 T(0.617)PKDS(0.383)PGIPPS(0.001)ANAHQLFR 70.335 0.0044276 21395000.0 58997.0 51766.0 141440.0 221570.0 196680.0 141470.0 102500.0 176860.0 139210.0 171590.0 True False 77756.81878616737 68498.34716069646 139564.41318474588 170490.45972237553 169374.37694392228 132623.8585360011 111622.30143118912 149530.3508384899 146568.35639715215 165582.6863279312 0.46959510387560977 0.4136806128693774 0.8428683957231073 1.0296394116032435 1.0228990765887307 0.800952451473965 0.6741181937954837 0.9030554712849013 0.8851671611781815 1.0 17.337192303948676 -5.294337445198467 5.379400726463268 0.8916839572100217 0.4391783218090481 0.7556433343511619 0.10324292966144938 0.08871810197602077 7.394637296598191 0.029941063896893008 0.0674205293995527 5.0776475791627525e-06 5.294337445198467 -0.4525056354009736 T(ph)PKDSPGIPPSANAHQLFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPKDSPGIPPSANAHQLFR 19 1 B4DG22;B1AXG1;B7ZB17;P51812 B4DG22 RPS6KA3 Ribosomal protein S6 kinase alpha-3 1 T(0.631)PKDS(0.368)PGIPPS(0.001)ANAHQLFR 80.508 0.0015307 16035000.0 53773.0 54297.0 82136.0 101210.0 106450.0 74341.0 64371.0 63125.0 64849.0 46353.0 True False 62875.70683483846 59687.247323628086 84094.43374251465 95539.53182724715 85591.88665771905 70442.42709014895 58273.312874318035 61468.03563646611 65797.29394274535 54756.431969853926 1.148279838055456 1.090049975434645 1.535790969521402 1.7448093016697344 1.5631384949414078 1.2864685399686182 1.0642277222591918 1.122571968719716 1.2016358914505232 1.0 15.740740820537031 -7.046369980074251 4.440036784122898 1.1110535352807365 1.4241429089984117 0.3935898893826295 0.18605040165887018 0.26751133675886196 11.464775369198096 0.08276086065545697 0.06552232215806232 8.987316163156178e-08 7.046369980074251 0.3130893737176752 T(ph)PKDSPGIPPSANAHQLFR ddPTM_PC-9_Lapatinib_30min_R1 2 TPKDSPGIPPSANAHQLFR 19 1 B4DG22;B1AXG1;B7ZB17;P51812 B4DG22 RPS6KA3 Ribosomal protein S6 kinase alpha-3 1 T(0.612)PKDS(0.388)PGIPPSANAHQLFR;T(0.632)PKDS(0.368)PGIPPSANAHQLFR 80.508 0.0015307 37615000.0 228400.0 144954.0 298040.0 214240.0 221100.0 147655.0 86505.0 131212.0 170167.0 102119.0 True False 225142.9741165697 144618.36791894736 273536.30166766996 229995.9242836895 208095.33269932505 141340.13985061637 90983.8056277843 137308.58853295626 151001.00052204976 119770.13308498573 1.8797923014480928 1.2074660367650254 2.2838440153821638 1.9203111690665857 1.7374559695251075 1.1800950388050844 0.7596535403632272 1.1464342987372795 1.2607567231715726 1.0 16.869908664514803 -6.784224330306636 3.8584828411288976 1.0443870012644678 1.8138238834211313 0.6479201060582893 0.2732702182429948 0.1457631147435686 4.69166353750292 0.10067246637245078 0.09251489552182524 1.6435225594021942e-07 6.784224330306636 0.7694368821566635 T(ph)PKLDPTMPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPKLDPTMPPK 11 1 Q702N8 Q702N8 XIRP1 Xin actin-binding repeat-containing protein 1 1 T(1)PKLDPTMPPK 64.827 0.033315 70740000.0 30415.0 32292.0 41784.0 36317.0 42059.0 34727.0 38911.0 42758.0 34381.0 27881.0 True False 35563.65877636752 35497.736349606756 42780.28902670242 34282.2762313026 33817.84087305775 32905.85498661039 35225.06838875563 41635.64780584583 34883.757082538265 32935.604594125456 1.0797937130539519 1.07779215797175 1.2989070507098845 1.0408880193265784 1.0267867036237632 0.999096734130687 1.0695133374001744 1.2641531351536857 1.0591503484578597 1.0 15.007360413260589 -12.136003114535097 1.6053239214825252 3.646245210571866e-05 1.1036878306930917 0.09448756327306351 0.09436602885153354 2189053.3413383067 111656.49477268303 7934065.310620635 0.025529919236308114 7.311338401513798e-13 12.136003114535097 1.103651368240986 T(ph)PLGASLDEQSSSTLK ddPTM_PC-9_Lapatinib_30min_R1 1 TPLGASLDEQSSSTLK 16 0 E9PHV5;P28290-3;P28290 E9PHV5 SSFA2 Sperm-specific antigen 2 1 T(0.903)PLGAS(0.095)LDEQS(0.001)SSTLK 120.57 0.00021921 3337300.0 11337.0 8259.2 10753.0 10043.0 11551.0 11069.0 10641.0 7235.7 13534.0 10725.0 True False 11175.332301048831 8240.076329843738 9868.929847780353 10781.595722465889 10871.592890139766 10595.604673099264 11191.93891318712 7571.897037221527 12009.65840066184 12578.801959835797 0.8884258084936663 0.6550764020416538 0.7845683459594893 0.8571242123766317 0.8642788816337866 0.842338142132383 0.8897460146779526 0.6019569320988316 0.9547537546905313 1.0 13.618706902012264 -14.522878745126159 0.2822770416684563 2.420333220078699 0.7972890417605502 0.2338537536322215 0.10283506888492312 343.8240719384928 3.278258200086717 286.29356527255743 0.11336009527353742 3.000000001065031e-15 14.522878745126159 -1.6230441783181488 T(ph)PLISR ddPTM_PC-9_AZD4547_30min_R2 1 TPLISR 6 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(1)PLISR 101.6 0.027788999999999998 0.0 8166.5 6720.7 10402.0 10068.0 11210.0 9442.5 9652.1 16286.0 8562.3 8579.9 True False 10763.277126247682 8893.034844548403 10264.062683453943 7746.978149049408 9653.684998685025 8852.05898230148 10511.118201404684 13769.372915049415 9014.885697718106 8279.520312518309 1.2999880089640012 1.0741002508445427 1.2396929165008612 0.9356795872988296 1.165971533892976 1.0691511884954874 1.2695322681330086 1.6630640901056386 1.0888173900712526 1.0 13.015331469923169 -7.385165616138569 5.844046441553998 1.315654510027482 1.126611842196868 0.06300214109615876 0.1895448710479342 0.4038015314018511 17.589913323798257 0.0768680620662828 0.051189102594208426 4.119403976257997e-08 7.385165616138569 -0.18904266783061385 T(ph)PLLPR ddPTM_PC-9_AZD4547_30min_R2 1 TPLLPR 6 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(1)PLLPR 79.469 0.042472 0.0 6030.0 6676.1 10467.0 10124.0 11452.0 9218.0 9384.1 13095.0 8663.3 10778.0 True False 7947.414568208362 8834.018766748943 10328.20074098369 7790.068214240782 9862.087475909088 8641.59700279111 10219.266720589476 11071.4686431642 9121.224351522511 10400.665500567879 0.764125580980797 0.8493705298249044 0.9930326804972016 0.7489970919471877 0.948216965094264 0.8308696210179317 0.9825589256794675 1.0644961750341548 0.8769846843958677 1.0 13.344388223651512 -7.27184974608891 23.232329108763892 0.9863846623253839 0.8610661227775829 0.36046426766612927 0.0814160752660334 307.30018952876264 685782.145647475 0.03255710198713787 0.02226591128935677 5.347493359163554e-08 7.27184974608891 -0.12531853954780103 T(ph)PLSPSPMK ddPTM_PC-9_Lapatinib_30min_R1 1 TPLSPSPMK 9 0 Q69YQ0-2;Q69YQ0;F8WAN1;A0A494C1J1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 T(0.982)PLS(0.018)PSPMK 84.81700000000001 0.031577 5316400.0 42363.0 45629.0 44990.0 36641.0 56844.0 71965.0 63098.0 67884.0 72202.0 58832.0 True False 41758.89585157726 45523.348853937394 41291.09586642224 39335.70137079284 53500.547679603915 68887.22470860861 66364.90569911488 71038.13846272604 64069.850439233436 69001.03281128766 0.6051923304653211 0.6597488037380561 0.5984127220146126 0.5700740955337996 0.7753586504411268 0.9983506318957529 0.9617958310945522 1.029522828404753 0.9285346585240164 1.0 16.07433033594129 -6.5673878420423435 2.9698896080457278 0.9850919055361725 0.6125786832181396 0.9632762174156481 0.03453895275943207 0.044541939548730945 0.8023909977778214 0.012064125380232323 0.012498733097943906 2.707772404632409e-07 6.5673878420423435 -0.37251322231803297 T(ph)PMYGSQTPLQDGSR ddPTM_PC-9_AZD4547_30min_R2 2 TPMYGSQTPLQDGSR 15 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 T(0.49)PMY(0.408)GS(0.038)QT(0.063)PLQDGS(0.001)R;T(0.966)PMY(0.012)GS(0.006)QT(0.017)PLQDGSR 138.25 0.00018932 18342400.0 27213.0 27499.0 40202.0 44728.0 45447.0 43307.0 32657.0 51117.0 37967.0 41121.0 True False 35866.16793443682 36387.51397774586 39668.895212479845 34416.65064071132 39137.46852232278 40599.0064439005 35563.40973500818 43218.04220180406 39973.85810883326 39681.36630625827 0.9038541580857878 0.9169924668649092 0.9996857191437871 0.8673252421573842 0.9862933705523715 1.0231252152599772 0.8962244258560059 1.0891268679674473 1.0073710113789316 1.0 15.276174080912526 -6.819922848068891 0.6837151702736493 1.0234259674547266 0.920053946290973 0.29888995287764397 0.05529935656060768 0.9305619525659187 0.9468229241482521 0.041915604024803314 0.040895655786613264 1.513830154791344e-07 6.819922848068891 -0.10337202116375355 T(ph)PNGPNIDKK ddPTM_PC-9_AZD4547_30min_R2 1 TPNGPNIDKK 10 1 Q92598-2;Q92598-3;Q92598;A0A0A0MSM0;Q92598-4;Q5TBM3 Q92598-2 HSPH1 Heat shock protein 105 kDa 1 T(1)PNGPNIDKK 73.36 0.023905000000000003 26051000.0 141140.0 152790.0 139610.0 106420.0 123470.0 165450.0 134170.0 165100.0 171430.0 126630.0 True False 186019.5841056267 202176.3795287024 137758.68018044648 81886.51317260995 106328.32174733639 155104.38534517158 146110.87007826954 139587.58862057352 180491.4398187186 122196.72224317241 1.5222960214550298 1.65451556979057 1.1273516805655854 0.6701203736844525 0.8701405389233127 1.269300702162147 1.1957020400883405 1.1423185995348808 1.4770563113758424 1.0 16.898846061827975 -5.288519773854499 7.532402790503212 1.0851085448193603 1.5887295011289067 0.47083461904410073 0.20953712825660809 0.17927754883344238 42.387659392657575 0.05981346282801737 0.12939526583465016 5.146123756731827e-06 5.288519773854499 0.5036209563095464 T(ph)PNGPNIDKK ddPTM_PC-9_Lapatinib_30min_R1 1 TPNGPNIDKK 10 1 Q92598-2;Q92598-3;Q92598;A0A0A0MSM0;Q92598-4;Q5TBM3 Q92598-2 HSPH1 Heat shock protein 105 kDa 1 T(1)PNGPNIDKK 70.628 0.02995 24673000.0 151140.0 152510.0 113890.0 117410.0 130770.0 127310.0 126140.0 117340.0 118340.0 98118.0 True False 148984.7158843189 152156.87246518684 104526.40382811341 126044.7230682783 123078.36570371193 121865.24807410498 132670.91199223965 122792.04477073014 105011.30302455464 115077.5655659828 1.2946460515702733 1.322211429454889 0.9083126090999936 1.0953023071730448 1.0695252814775758 1.0589835427499574 1.1528825044197621 1.0670372123950087 0.9125262818002836 1.0 16.812247081135574 -5.2439512840084594 24.83173113585978 1.044194288908976 1.308428809736542 0.6904686522740618 0.07344433823022833 427.79398068967294 607431.5672508407 0.018738919665862462 0.04933428586000551 5.702282327429273e-06 5.2439512840084594 0.26423452082756604 T(ph)PPAPSPFDLPELK ddPTM_PC-9_AZD4547_30min_R2 2 TPPAPSPFDLPELK 14 0 O95239 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 T(1)PPAPSPFDLPELK;T(1)PPAPSPFDLPELK 131.96 3.6054000000000004e-05 58237000.0 157725.0 165851.0 172522.0 165649.0 178339.0 208523.0 172717.0 224996.0 191825.0 172177.0 True False 207878.26911619608 219459.0923569267 170234.24555612766 127461.1823015381 153579.70820521776 195484.02384606312 188088.47840283587 190228.0380937282 201964.47788150108 166149.13563660035 1.251154682928145 1.3208560581195279 1.0245870067507437 0.767149235012091 0.9243485234923261 1.1765575733937235 1.1320460842734748 1.1449234289716257 1.2155614117863103 1.0 17.342119262103928 -5.2633381994482145 24.82142047622852 1.0464480180159752 1.2860053831653986 0.3605099272399571 0.126701554961124 171.75255269965626 2245196.8689127197 0.03746712676782883 0.08502621992179647 5.453330268681941e-06 5.2633381994482145 0.23955736514942338 T(ph)PPAPSPFDLPELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TPPAPSPFDLPELK 14 0 O95239 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 T(1)PPAPSPFDLPELK;T(1)PPAPSPFDLPELK;T(1)PPAPSPFDLPELK 165.86 0.0011296 102278500.0 353664.7 404803.4 386170.4 342880.0 382386.7 297015.3 371099.5 242411.7 270010.2 279909.8 True False 413533.14851377165 444989.60629952943 395378.1668953968 323669.5452319593 307460.7711208936 281439.29480244726 335946.2688322853 236048.64973142714 273958.5883658871 330655.2309752421 1.2506475318539119 1.3457812386244938 1.1957414547148077 0.9788732036003814 0.9298530382055707 0.8511563357771893 1.0160016759494102 0.7138814923182066 0.82853244921566 1.0 18.334968199668737 -5.776335245914288 1.8029193465592301 0.8774692171927395 1.3065540247218115 0.8001543662216495 0.08464618924796766 0.14445041809369363 0.9573529812270294 0.0266677185601211 0.054275101653236985 1.6736504325159474e-06 5.776335245914288 0.42908480752907197 T(ph)PPAPSPFDLPELK ddPTM_PC-9_Lapatinib_30min_R1 4 TPPAPSPFDLPELK 14 0 O95239 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 T(1)PPAPSPFDLPELK;T(1)PPAPSPFDLPELK;T(1)PPAPSPFDLPELK;T(1)PPAPSPFDLPELK 150.34 0.00041703 60467700.0 125344.0 138014.0 134561.0 111874.0 129711.0 130348.0 98221.0 114160.0 112514.0 97281.3 True False 123556.57157472546 137694.43706255456 123497.91400048087 120101.58716072355 122081.654001638 124773.31989602902 103306.40278095593 119464.29036156966 99841.48849505429 114096.24308581585 1.0829153373770086 1.2068270903450316 1.0824012312797513 1.052634021177988 1.0699883773545116 1.0935795651236524 0.905432115790662 1.0470484139579979 0.8750637689267293 1.0 16.79989176237632 -6.778054231659935 0.7130471957020476 0.9501059526891966 1.1343748565611755 0.5245444370580005 0.06256820800274994 0.5457591619699775 0.6078458317938695 0.04435346782060154 0.04407356236217107 1.6670390313687023e-07 6.778054231659935 0.18426890387197892 T(ph)PPEDCEGPFRPAEILK ddPTM_PC-9_Lapatinib_30min_R1 1 TPPEDCEGPFRPAEILK 17 1 P49790-3;P49790 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 T(1)PPEDCEGPFRPAEILK 59.673 0.027444 12064000.0 11827.0 23917.0 19646.0 20073.0 22208.0 22739.0 23935.0 28064.0 20796.0 18104.0 True False 11658.34481119383 23861.621655956103 18030.781715753088 21549.23538156504 20901.769102607897 21766.505977197972 25174.23718514555 29367.95589266895 18453.735488411676 21233.25227793634 0.549060721296479 1.1237855295842232 0.8491766348242862 1.0148815216572846 0.984388487877908 1.0251140848458595 1.185604393317755 1.3831115228252364 0.8690960408164657 1.0 14.374037744004886 -4.756642146999258 24.928775862889502 1.0546172424887252 0.54905992299996 0.5081312571901017 0.14725450157726136 122.50880438375955 636538.0868950639 0.03795265277804455 0.30118621276068547 1.751289133718192e-05 4.756642146999258 -0.5055573194887653 T(ph)PPFSESEEQLHLHDAGMKPR ddPTM_PC-9_AZD4547_30min_R2 1 TPPFSESEEQLHLHDAGMKPR 21 1 Q8IVM0-2 Q8IVM0-2 CCDC50 Coiled-coil domain-containing protein 50 1 T(0.735)PPFS(0.205)ES(0.06)EEQLHLHDAGMKPR 63.522 0.0044821999999999996 6862400.0 24738.0 34221.0 36966.0 35759.0 40247.0 46866.0 36551.0 47547.0 39467.0 37318.0 True False 32604.169417634905 45282.26902187135 36475.80668684466 27515.315021042683 34659.398763789104 43935.46161128317 39803.968191330634 40199.703671365256 41553.14504652261 36011.508178715165 0.9053819477881743 1.2574388386386917 1.0128930592361007 0.7640700546195338 0.9624534077213341 1.22003947719278 1.1053124460601467 1.1163015853672453 1.1538851647175072 1.0 15.13617040108236 -6.741873673405096 24.98715243168784 1.1255143932173202 0.9856174042317228 0.23349849538258172 0.12516994915194926 394.2515228995494 503493.482155837 0.043777970853969624 0.04371672872611764 1.811867047757787e-07 6.741873673405096 -0.13989698898559733 T(ph)PPGPCCSPGVGWAQR ddPTM_PC-9_AZD4547_30min_R2 2 TPPGPCCSPGVGWAQR 16 0 H3BSW6;Q2VPK5-3;Q2VPK5-5;Q2VPK5 H3BSW6 CTU2 Cytoplasmic tRNA 2-thiolation protein 2 1 T(1)PPGPCCSPGVGWAQR;T(0.978)PPGPCCS(0.022)PGVGWAQR 157.97 7.1195e-05 16646200.0 7296.3 9573.4 13034.3 16482.0 15903.6 11322.099999999999 11360.4 19856.8 10088.7 15227.9 True False 9616.371627532115 12667.814331959427 12861.45666553968 12682.329544361566 13695.659656118385 10614.127297168725 12371.453591989075 16788.387823870406 10621.96808551074 14694.775856012022 0.6544075065696088 0.8620624401546546 0.8752400711357374 0.8630502206110813 0.93200874857272 0.7223061720146078 0.8418946783000835 1.1424732155408708 0.7228397486012018 1.0 13.843015732830214 -4.751594067730968 3.7608921865759735 0.8850880285627667 0.6222895088129444 0.2604583682211099 0.11701995369555526 0.41447576585938334 9.951856415987507 0.028596995084328242 0.3174187515984124 1.7717642412875872e-05 4.751594067730968 -0.26279851974982227 T(ph)PPGPCCSPGVGWAQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPPGPCCSPGVGWAQR 16 0 H3BSW6;Q2VPK5-3;Q2VPK5-5;Q2VPK5 H3BSW6 CTU2 Cytoplasmic tRNA 2-thiolation protein 2 1 T(1)PPGPCCSPGVGWAQR 163.9 0.00015248 5891800.0 2163.7 3349.1 2995.3 6347.1 3276.1 2465.4 5013.9 2712.3 6010.4 5481.7 True False 2529.9716749770323 3681.5765145691817 3066.7193117385077 5991.492564575842 2634.1717226806263 2336.110083911345 4538.947094507514 2641.104998919399 6098.29072944033 6475.488816886674 0.39069972113601886 0.5685403247038937 0.4735888515074209 0.9252571866005429 0.4067911778044117 0.3607619671613478 0.7009427740298032 0.4078618732275421 0.9417498665949832 1.0 12.660773386662871 -8.30937884327252 7.682748618694986 0.9765717064034322 0.5380936979924402 0.5351133546065592 0.16447811266219603 0.2575089788933051 36.17447276841699 0.15382999886479895 0.04044757911374942 4.904798346693516e-09 8.30937884327252 -0.43847800841099194 T(ph)PPGPCCSPGVGWAQR ddPTM_PC-9_Lapatinib_30min_R1 1 TPPGPCCSPGVGWAQR 16 0 H3BSW6;Q2VPK5-3;Q2VPK5-5;Q2VPK5 H3BSW6 CTU2 Cytoplasmic tRNA 2-thiolation protein 2 1 T(0.998)PPGPCCS(0.002)PGVGWAQR 133.42 7.5059e-06 6383800.0 5935.5 6542.9 7563.8 5098.6 5338.6 6168.0 5257.2 5013.4 6063.1 4666.3 True False 5850.858681562612 6527.750317044578 6941.933561112347 5473.568052431002 5024.594044091432 5904.2090183102655 5529.392092322839 5246.340866316515 5380.209830726527 5472.863737546087 1.0690671213725504 1.1927485554338833 1.2684279920013064 1.0001286922018693 0.9180922977527577 1.0788152787004313 1.0103288438169846 0.9586098097645785 0.9830703062851874 1.0 12.418080221672723 -5.783547978111932 22.994508091343004 0.9922073972832481 1.1783478392462534 0.6706423272063706 0.059095015519302116 52.20108489262858 54292.55160926286 0.016953930600288145 0.02518043848077098 1.6460841073054744e-06 5.783547978111932 0.18614044196300528 T(ph)PPPPSSTFPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPPPPSSTFPK 11 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PGF6 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 T(0.999)PPPPSSTFPK 80.014 0.040681999999999996 5249500.0 16755.0 25704.0 20754.0 16063.0 22373.0 15906.0 21947.0 19305.0 18579.0 16869.0 True False 19591.290573665574 28255.72324818199 21248.854069983292 15163.042186948644 17989.171255924317 15071.861359087314 19868.021277479893 18798.264205338273 18850.682726985207 19927.216165069472 0.9831423722901774 1.4179463410303945 1.0663232582998987 0.7609212476717157 0.9027438206575806 0.7563455544536554 0.9970294452020176 0.9433462280742382 0.9459767270467349 1.0 14.282452559100758 -5.528978378409687 11.119850616720143 0.8978419913308079 1.2109865379975069 0.48362245500397283 0.12577783327305952 0.14429691216641272 243.51181851418153 0.03224396762297731 0.05748787768998243 2.9581597364995868e-06 5.528978378409687 0.313144546666699 T(ph)PPPPTLSPAAITVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPPPPTLSPAAITVGR 16 0 Q8NDX5-2;Q8NDX5;Q8NDX5-7;E7EX82;H7C4H9 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 1 T(0.862)PPPPT(0.078)LS(0.06)PAAITVGR 99.927 0.004514100000000001 4250800.0 1731.8 1543.9 0.0 1508.9 2205.5 1087.7 1503.3 2130.6 1231.3 1729.6 True False 2024.9595353908685 1697.1681887203601 0.0 1424.3612249198043 1773.3481073142227 1030.659097213584 1360.896541050509 2074.6740075573016 1249.3054331092578 2043.1627884939337 0.991090649650837 0.8306573505928939 0.0 0.6971354573121099 0.8679426413307977 0.5044429660806952 0.6660734762371333 1.015422764764914 0.6114566299585713 1.0 10.996588439686086 -8.330328976150948 0.6197865345887958 0.9775495158994482 0.6283478368552595 0.10451206768811083 0.2764351618304515 1.7566580933286011 1.5968092943705081 0.2888301702608125 0.1301409787261274 4.6738096814376765e-09 8.330328976150948 -0.34920167904418864 T(ph)PPPPTLSPAAITVGR ddPTM_PC-9_Lapatinib_30min_R1 1 TPPPPTLSPAAITVGR 16 0 Q8NDX5-2;Q8NDX5;Q8NDX5-7;E7EX82;H7C4H9 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 1 T(0.76)PPPPT(0.098)LS(0.141)PAAIT(0.001)VGR 97.223 0.005422 4592600.0 975.02 938.79 1252.9 770.83 1192.3 862.19 828.15 1113.9 1673.1 1298.1 True False 961.1160360032309 936.6162894340852 1149.8913983338616 827.5194096134995 1122.1712581519903 825.3161435630552 871.027554830929 1165.6558604918744 1484.6578594759364 1522.4748553904756 0.631285326388349 0.6151932730566294 0.7552777599331478 0.5435356824998349 0.737070470608319 0.5420885216205313 0.5721129329308581 0.7656322574817919 0.9751608404036072 1.0 10.572202685993679 -8.126603550528717 2.7734582874789617 0.9973528888213898 0.6307028478157842 0.810339118645542 0.06889317848543906 0.11223459074269254 1.5505730350364697 0.05667396437712479 0.017991923000521624 7.47130471717117e-09 8.126603550528717 -0.3666500410056056 T(ph)PPRDLPTIPGVTSPSSDEPPMEASQSHLR ddPTM_PC-9_AZD4547_30min_R2 4 TPPRDLPTIPGVTSPSSDEPPMEASQSHLR 30 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 T(0.853)PPRDLPT(0.136)IPGVT(0.005)S(0.002)PS(0.002)S(0.002)DEPPMEASQSHLR;T(0.661)PPRDLPT(0.321)IPGVT(0.009)S(0.007)PS(0.001)S(0.001)DEPPMEASQSHLR;T(0.476)PPRDLPT(0.177)IPGVT(0.225)S(0.109)PS(0.006)S(0.006)DEPPMEASQSHLR;T(0.692)PPRDLPT(0.26)IPGVT(0.019)S(0.025)PS(0.002)S(0.002)DEPPMEASQSHLR 53.631 0.0029139 211712000.0 14834.57 23170.0 45629.600000000006 60979.6 63945.5 52600.2 42192.6 68925.5 46009.9 50217.4 True False 19551.654681775573 30659.249385954827 45024.521690148984 46921.69534542839 55067.771104675594 49311.10117880376 45947.659662103295 58274.647725422925 48441.88938292748 48459.30411098696 0.4034654446749002 0.6326803479417608 0.9291202693919985 0.9682701022276967 1.1363714794284536 1.017577575316928 0.9481700264797197 1.2025481751028815 0.9996406318997154 1.0 15.56448606698756 -5.034965167938101 1.2821879339893867 1.053467573664684 0.2653274861118148 0.8978433974864731 0.07156465723622908 0.2535190563478569 0.5004806658079601 0.021501795952138216 0.2338785026666027 9.226454238438926e-06 5.034965167938101 -0.7881400875528691 down T(ph)PPRDLPTIPGVTSPSSDEPPMEASQSHLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TPPRDLPTIPGVTSPSSDEPPMEASQSHLR 30 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 T(0.83)PPRDLPT(0.15)IPGVT(0.014)S(0.002)PS(0.003)S(0.001)DEPPMEASQSHLR;T(0.92)PPRDLPT(0.071)IPGVT(0.004)S(0.004)PS(0.001)SDEPPMEASQSHLR;T(0.571)PPRDLPT(0.411)IPGVT(0.008)S(0.008)PS(0.001)S(0.001)DEPPMEASQSHLR;T(0.727)PPRDLPT(0.208)IPGVT(0.049)S(0.013)PS(0.002)S(0.002)DEPPMEASQSHLR;T(0.754)PPRDLPT(0.241)IPGVT(0.003)S(0.001)PS(0.001)SDEPPMEASQSHLR 66.252 0.00011856 102203000.0 21295.600000000002 38496.2 94108.8 61783.8 77508.8 65396.4 57323.2 41513.3 48482.200000000004 37860.100000000006 True False 24900.524472727684 42317.848323477396 96352.71070161152 58322.25399178223 62321.507041576406 61966.897660217386 51893.13151197139 40423.61986197716 49191.16045568883 44723.83642961334 0.5567618178712439 0.9462034499226716 2.1543927890276597 1.3040530206653933 1.3934740848911384 1.3855452172074123 1.160301433300364 0.9038495596323923 1.0998868697927153 1.0 15.448756328029802 -7.5166765455319124 4.543117345164082 1.0029325474150774 1.317343757314047 0.10108622042821458 0.38044065975878455 0.4683381644289894 25.05393297375 0.1891313280228566 0.1137088850233557 3.0431506639918256e-08 7.5166765455319124 0.31441120989896953 T(ph)PPRDLPTIPGVTSPSSDEPPMEASQSHLR ddPTM_PC-9_Lapatinib_30min_R1 3 TPPRDLPTIPGVTSPSSDEPPMEASQSHLR 30 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 T(0.759)PPRDLPT(0.215)IPGVT(0.018)S(0.004)PS(0.002)S(0.002)DEPPMEASQSHLR;T(0.959)PPRDLPT(0.039)IPGVT(0.001)S(0.001)PSSDEPPMEASQSHLR;T(0.688)PPRDLPT(0.263)IPGVT(0.032)S(0.007)PS(0.007)S(0.003)DEPPMEASQSHLR 63.297 0.00023121 80431000.0 30171.8 25979.4 44175.5 31302.3 36076.2 37675.1 29589.7 32911.4 40326.3 23733.6 True False 29741.544599169516 25919.246295469577 40543.56091236131 33604.37556341172 33954.268844538135 36063.82379794762 31121.709882485946 34440.58379297268 35784.327439235225 27835.92113696586 1.068459148624078 0.931143832745274 1.4565194632097092 1.2072305923724365 1.2198004397794893 1.2955857871739396 1.1180413153691755 1.2372712087920053 1.2855449353789823 1.0 14.764660204723532 -5.233854246305323 24.9935853454719 1.2334968351685616 0.9998014513805316 0.3807052062125219 0.11596268241857975 693.6940016353959 628521.1785394956 0.027643430901124547 0.07309911296350863 5.8364094731287665e-06 5.233854246305323 -0.23369538378803 T(ph)PPSAPSQSR ddPTM_PC-9_Lapatinib_30min_R1 1 TPPSAPSQSR 10 0 Q9UQ35;I3L3Q8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(1)PPSAPSQSR 91.469 0.019686000000000002 20485000.0 4426.8 4827.0 5433.5 4702.3 7789.0 4337.8 4471.1 3594.0 5560.6 3135.5 True False 4363.6730202243025 4815.823378069995 4986.778603916538 5048.1228284129575 7330.866333763191 4152.282405905682 4702.591680739681 3760.9903605420564 4934.306672286111 3677.4669972088705 1.186597466010232 1.3095490406100492 1.3560362629226612 1.3727173710177112 1.9934553700487816 1.129114798054527 1.2787583639251856 1.0227121992927684 1.3417677646138386 1.0 11.844496678983322 T(ph)PPTANHPVEPVTSVTQPSELLQQK ddPTM_PC-9_AZD4547_30min_R2 2 TPPTANHPVEPVTSVTQPSELLQQK 25 0 O95487-2;O95487;O95487-3 O95487-2 SEC24B Protein transport protein Sec24B 1 T(0.874)PPT(0.126)ANHPVEPVTSVTQPSELLQQK;T(0.656)PPT(0.344)ANHPVEPVTSVTQPSELLQQK 100.06 3.3772000000000005e-06 17837200.0 47244.0 53516.0 59407.0 61054.0 64852.0 74297.0 62183.0 73399.0 64565.0 58580.0 True False 62266.60926375382 70814.00043758127 58619.22436415577 46978.943574896926 55848.41922700457 69651.19684490893 67717.16653556704 62056.87109122633 67977.77408794005 56529.13203036433 1.101495937179924 1.2526992347864796 1.0369737206060188 0.8310572246123014 0.9879581946704202 1.2321292463414466 1.1979162619937826 1.0977856701902446 1.2025264080019156 1.0 15.786706925028495 -6.754335569978981 24.999778299904467 1.15542342064917 1.0417379524242292 0.1670196515490635 0.11522313480723716 317.3145022604872 1116694.9944535806 0.04214029467295156 0.041293961197927435 1.7606151313667352e-07 6.754335569978981 -0.11368546822494086 T(ph)PPTPPSSIVAK ddPTM_PC-9_Lapatinib_30min_R1 1 TPPTPPSSIVAK 12 0 Q96QT6;Q96QT6-4 Q96QT6 PHF12 PHD finger protein 12 1 T(1)PPTPPSSIVAK 138.42 0.00016961 12471000.0 109630.0 104530.0 117490.0 88310.0 104190.0 108170.0 83377.0 90299.0 107410.0 100110.0 True False 108066.65609632015 104287.96720730393 107830.42572451536 94804.61199352393 98061.74904542122 103543.82125658574 87693.8530932058 94494.62119270646 95312.35472255721 117413.88011180998 0.9203908089351214 0.8882081667686426 0.9183788630597288 0.8074395625393193 0.8351802099721067 0.8818703645427937 0.7468780778703283 0.8047994078955729 0.8117639467479816 1.0 16.84124344152883 -5.7561078408968696 24.96883962904536 0.8305217804210031 0.9069141840587158 0.17933459082727676 0.06370775334619871 186.30007419366464 872474.0663171889 0.016590129758054486 0.027704623556713937 1.753445044857633e-06 5.7561078408968696 0.07639240363771271 T(ph)PPVALNSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPPVALNSSR 10 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(1)PPVALNSSR 84.18799999999999 0.03106 85195000.0 12859.0 22874.0 18238.0 14266.0 15177.0 12829.0 5779.7 14336.0 11556.0 12067.0 True False 15035.774723173114 25144.779551000418 18672.863088000155 13466.722270996033 12203.175799006107 12156.224655836231 5232.204974595645 13959.69519024757 11724.98463819587 14254.651577680555 1.0547977718877124 1.7639701268020644 1.3099487550602418 0.9447247586241789 0.856083765534713 0.8527900236348134 0.3670524632666611 0.9793080605425096 0.8225374415011623 1.0 13.799145155879287 -5.80089028376619 2.7037517820122576 0.7964426004822022 1.4372939967794813 0.549728072225456 0.2285880241226505 0.18287172133202992 2.723548497653407 0.06604616950551034 0.11468054516613721 1.581647561951323e-06 5.80089028376619 0.6408513962972792 T(ph)PPVALNSSR ddPTM_PC-9_Lapatinib_30min_R1 1 TPPVALNSSR 10 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(0.995)PPVALNS(0.003)S(0.003)R 80.014 0.044587 292790000.0 13269.0 16308.0 10544.0 13681.0 13087.0 10911.0 12141.0 16296.0 14515.0 11603.0 True False 13079.781626763423 16270.239827960526 9677.113021017021 14687.146378478124 12317.24839003196 10444.361964783286 12769.601573630762 17053.171651472836 12880.167850273872 13608.563089974336 0.9611434756399465 1.1955883747893334 0.7111046887930672 1.0792576910120952 0.905110136066187 0.7674845533455202 0.9383504701564229 1.2531206666511472 0.9464752277749967 1.0 13.73222712218796 -10.940165214349038 5.823287025473152 1.0000104291877157 0.9742036009854862 0.0024904070408193757 0.1602482121949548 2.1766851318811996e-05 2.1781957009291712e-06 0.1556539274232222 0.03773636685237396 1.1477169238540876e-11 10.940165214349038 -0.02580682820222946 T(ph)PPVVIK ddPTM_PC-9_AZD4547_30min_R2 1 TPPVVIK 7 0 Q96A49 Q96A49 SYAP1 Synapse-associated protein 1 1 T(1)PPVVIK 93.429 0.034038 562190000.0 116150.0 140960.0 147010.0 120710.0 122510.0 163670.0 138170.0 178090.0 152880.0 119860.0 True False 153083.2839299173 186522.56337696122 145060.5513453723 92882.1744509092 105501.60117652996 153435.68902655886 150466.86232924295 150570.2826010778 160960.92468929407 115663.73788254481 1.3235201173022058 1.6126278364475193 1.2541575605370772 0.8030362510437797 0.9121406856457087 1.3265669243922502 1.3008991848598246 1.301793330888028 1.3916282461210794 1.0 16.81957710571956 -1.5228787459519504 0.01655073930540095 2.565461068037939e-14 2.7275834912131396 0.0624623156379851 0.2243899098751634 19771.924896032448 25.345397314586794 1632.0670325102453 2660.743316069582 0.02999999995360663 1.5228787459519504 2.727583491213114 T(ph)PQAPASANLVGPR ddPTM_PC-9_AZD4547_30min_R2 2 TPQAPASANLVGPR 14 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(1)PQAPASANLVGPR;T(1)PQAPASANLVGPR 158.91 0.00060953 26018000.0 4729.5 4808.5 5981.5 11325.3 4686.7 6532.299999999999 9937.4 11803.1 11377.0 6719.799999999999 True False 6233.382620288798 6362.75358965748 5902.1814017573315 8714.427059140768 4036.0326033306937 6123.834248354567 10821.80934870534 9979.202103255544 11978.364993394165 6484.541847347929 0.9612680073671124 0.9812186796604206 0.9101925071500967 1.3438770639910087 0.6224082901063187 0.9443742352991543 1.6688625971519147 1.5389216907185004 1.8472183965152633 1.0 12.662788931936518 -7.255924594298583 24.805415983593402 1.5586608221846854 0.9612596527512417 0.5192942206593385 0.25930853356872763 298.4355099216264 1342362.2328407946 0.09657713153769301 0.07262231120069323 5.5472201989615965e-08 7.255924594298583 -0.5974011694334437 T(ph)PQAPASANLVGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPQAPASANLVGPR 14 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(1)PQAPASANLVGPR 108.66 0.0016248 8901500.0 2668.1 2585.1 3409.8 3288.5 7507.4 2266.2 7020.2 3297.7 3317.4 5370.7 True False 3119.756632622922 2841.7316436692827 3491.102563738511 3104.256006460849 6036.378862321829 2147.356482582904 6355.195834153385 3211.1388692019677 3365.910699095793 6344.365395562195 0.4917365943022691 0.44791424618402953 0.550268205891876 0.4892933828546883 0.9514551079520421 0.3384667100171994 1.001707095653533 0.5061402786554696 0.5305354419608628 1.0 12.631260148261491 -14.522878745280336 0.09921582707345199 2.163268957168062 0.3389812846060751 0.28029380185589803 0.20201673046849059 256.55460704391436 1.728378534808186 63.38984727191051 3.398520770565765 3.0000000000000132e-15 14.522878745280336 -1.824287672561987 T(ph)PQAPASANLVGPR ddPTM_PC-9_Lapatinib_30min_R1 1 TPQAPASANLVGPR 14 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(1)PQAPASANLVGPR 103.88 0.0027388 14822000.0 3254.0 7486.6 9691.6 3525.0 5464.3 11750.0 6174.4 2456.7 7815.0 2731.1 True False 3207.597363289483 7469.265237675336 8894.794058657866 3784.240259055288 5142.900617227139 11247.479890587807 6494.080220428771 2570.847250624281 6934.792404401675 3203.1669960379977 1.0013831209103257 2.331837599136755 2.7768749083828133 1.18140585980563 1.6055674348506965 3.5113623187613485 2.0273935853052025 0.8025954481312295 2.164979975436601 1.0 11.645283299157919 -7.62382273778625 9.405250767152054 1.3658348302717522 2.110287700198016 0.16135377435715526 0.7677029407983669 0.5562712273929393 47.26928010046713 0.36629231250678473 0.21098705357999778 2.3778106189322674e-08 7.62382273778625 0.7444528699262638 T(ph)PQASTYSYETSDLCYTAEKK ddPTM_PC-9_Lapatinib_30min_R1 1 TPQASTYSYETSDLCYTAEKK 21 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.951)PQAS(0.011)T(0.007)Y(0.016)S(0.004)Y(0.01)ETSDLCYTAEKK 102.79 0.00069388 0.0 9445.4 9826.9 11601.0 12446.0 11187.0 10925.0 13053.0 11735.0 14266.0 8232.3 True False 9310.706863925776 9804.146416812933 10647.21056115502 13361.320358638897 10529.002654488224 10457.763217418871 13728.82047118048 12280.250940723716 12659.21285236011 9655.242086149763 0.9643162523373479 1.0154221229602074 1.1027388506838387 1.38384105125706 1.0904959772672973 1.083117660241819 1.4219032882535567 1.271873955220602 1.31112329855711 1.0 13.237096717023848 -5.532759013732142 6.063967668569893 1.2327808044866106 1.0047566002257935 0.3469754401057019 0.12845135617211506 0.16119439686621317 23.329705049341438 0.03496937102488695 0.06464117614502635 2.9325200239722267e-06 5.532759013732142 -0.22802420426081715 T(ph)PQMPPTTPSS(ph)SS(ph)FTKVTK ddPTM_PC-9_AZD4547_30min_R2 1 TPQMPPTTPSSSSFTKVTK 19 1 Q6K0P9-4;Q6K0P9-3 Q6K0P9-4 3 T(0.705)PQMPPT(0.192)T(0.103)PS(0.156)S(0.441)S(0.441)S(0.475)FT(0.286)KVT(0.201)K 46.295 0.03096 67553000.0 23194.0 18814.0 63094.0 114420.0 86728.0 60896.0 39145.0 75242.0 43820.0 69599.0 True False 30569.209534829963 24895.257572177547 62257.33233511272 88042.23677137782 74687.31423425117 57088.163493379005 42628.82916608675 63615.077789153205 46136.235739696975 67162.3601942867 0.45515389045887633 0.3706727622460074 0.9269676073773352 1.3108865816610673 1.1120412388456324 0.8500023425060533 0.6347130899326712 0.9471834760590315 0.6869358909698002 1.0 16.03536530935928 -5.2652644401630235 23.07367062204647 0.9378935261747825 0.41291324092811066 0.5607215075061878 0.18431105800945558 80.66161787399108 486582.7051838774 0.05317229402522138 0.11820996397698422 5.4291964923664875e-06 5.2652644401630235 -0.5249802852466718 T(ph)PQPGSPSPNTPCLPEAAVSQPGSAVASDWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPQPGSPSPNTPCLPEAAVSQPGSAVASDWR 31 0 H3BU45;Q9Y4R8 H3BU45 TELO2 Telomere length regulation protein TEL2 homolog 1 T(0.454)PQPGS(0.41)PS(0.135)PNT(0.002)PCLPEAAVSQPGSAVASDWR 67.262 0.0068409 0.0 4852.5 6504.0 7713.2 5379.9 8090.9 5608.4 6952.9 8845.2 6687.6 4055.7 True False 5673.932408756318 7149.674136561448 7897.1119404738965 5078.481644871134 6505.546226011623 5314.285630976064 6294.270977363193 8613.02287226408 6785.393498303806 4790.966305096465 1.1842981243096167 1.4923240284440888 1.6483338511634327 1.060011972839137 1.3578776830659918 1.1092304333935536 1.3137790116928114 1.797763190924938 1.4162891296241717 1.0 12.22610095168255 -7.606863034123653 23.629213165824936 1.475369816805298 1.3139270742922449 0.0064796100327531025 0.24539152645569007 45.76968478850213 12869.377663468635 0.11353896912944082 0.06555174897383038 2.4725037893985734e-08 7.606863034123653 -0.16144274251305313 T(ph)PQPSSPMDQMGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPQPSSPMDQMGK 13 0 O14497-2;O14497 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 T(0.464)PQPS(0.107)S(0.429)PMDQMGK 67.01899999999999 0.032053 3371400.0 14653.0 12704.0 14737.0 17518.0 20628.0 21184.0 18647.0 17660.0 18524.0 16391.0 True False 17133.463490057988 13965.169162188908 15088.385970383733 16536.52325412229 16586.091479337018 20073.07374769933 16880.621167410933 17196.443712316704 18794.878456034996 19362.558548915404 0.8848760067928998 0.7212460650233214 0.7792557957806103 0.854046391252802 0.8566063951432745 1.0366953157037053 0.8718176952062208 0.8881286875840055 0.9706815557744456 1.0 14.240981981022767 -6.289103332370641 2.0261505219533715 0.9403427967420022 0.7922123247533064 0.5300987282277457 0.06264114505694968 0.2650105684477067 2.1369618687343244 0.02138413271232699 0.02723197572106045 5.139213589153581e-07 6.289103332370641 -0.14813047198869578 T(ph)PQPSSPMDQMGK ddPTM_PC-9_Lapatinib_30min_R1 1 TPQPSSPMDQMGK 13 0 O14497-2;O14497 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 T(1)PQPSSPMDQMGK 99.991 0.0017429000000000001 0.0 6708.0 8404.1 5892.9 4138.2 4143.4 5162.2 5394.2 6179.0 6523.8 4928.0 True False 6612.34268990346 8384.640822796368 5408.4085092518235 4442.537032630521 3899.6933582378233 4941.424739675946 5673.485281976696 6466.0988975485125 5789.0209453404495 5779.798233852757 1.1440438614577273 1.450680539968823 0.9357434793440239 0.7686318540689212 0.674710984787842 0.8549476192323828 0.9816061136436601 1.1187412840254587 1.0015956805262984 1.0 12.496803415432895 -5.320095193636756 8.000814814246509 0.906635736008477 1.2965940774725386 0.546342795721823 0.13841795687171982 0.2237591234290197 28.189186838473763 0.04020137317855845 0.08439528944621011 4.785251921962204e-06 5.320095193636756 0.3899583414640616 T(ph)PS(ph)LISGIPTPPS(ph)LPGNS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 TPSLISGIPTPPSLPGNSK 19 0 Q5JT55;Q96SF7-2;Q96SF7 Q5JT55 TBX15 T-box transcription factor TBX15 4 T(0.943)PS(0.793)LIS(0.232)GIPT(0.079)PPS(0.96)LPGNS(0.993)K 44.998000000000005 0.034921 43119000.0 10293.0 12488.0 11224.0 18055.0 16220.0 13899.0 9878.8 14759.0 10685.0 15967.0 True False 13565.959892299945 16524.501783849963 11075.162426368679 13892.698696969304 13968.13297757993 13029.893332804697 10757.994062228587 12478.335678080215 11249.78728614016 15408.00018997656 0.8804490994960575 1.0724624597681227 0.7187929835030413 0.9016548887380589 0.9065506753216869 0.8456576565517631 0.6982083287633288 0.8098608206273132 0.7301263724969668 1.0 13.911392005631507 -7.003876441926458 8.287345943314692 0.7905679726179012 0.8944110208146007 0.11344230566496871 0.10925156624893675 0.21782079105061952 147.61240765899043 0.03854401085733789 0.032262140170283976 9.911138796357767e-08 7.003876441926458 0.10384304819669943 T(ph)PSASNDDQQE ddPTM_PC-9_AZD4547_30min_R2 1 TPSASNDDQQE 11 0 O43765 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 T(0.867)PS(0.117)AS(0.016)NDDQQE 143.0 0.00035830000000000004 7996500.0 9683.4 7143.6 14094.0 16951.0 13176.0 14663.0 8843.0 12021.0 7307.5 10573.0 True False 12762.51977276763 9452.628999288163 13907.104351143995 13043.208840339337 11346.739834315242 13746.120292029307 9630.009868839072 10163.43066509942 7693.759531443074 10202.842488170734 1.2508788396532249 0.9264701489067997 1.3630617513960461 1.2783897090895746 1.1121155548045314 1.347283397540115 0.9438555853434168 0.9961371722520456 0.754080006661211 1.0 13.316683519225819 -7.353540225428523 6.94531158720419 0.919974703117419 1.2048443411219574 0.5289213114207627 0.1337857082512032 0.21840214764232418 14.164351093442354 0.055892163190181206 0.03748094950918005 4.4305717553789445e-08 7.353540225428523 0.28486963800453835 T(ph)PSASNDDQQE ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TPSASNDDQQE 11 0 O43765 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 T(0.472)PS(0.472)AS(0.056)NDDQQE;T(0.742)PS(0.254)AS(0.005)NDDQQE;T(0.5)PS(0.5)AS(0.001)NDDQQE 164.9 0.00068179 10439100.0 18510.399999999998 16445.300000000003 24689.7 16912.3 33632.7 32535.199999999997 41226.799999999996 42442.2 33465.5 29773.0 True False 21643.845122935178 18077.880700798585 25278.39608420866 15964.758661416392 27042.613869357087 30828.996837053775 37321.49904781557 41328.13722122807 33954.86962699413 35170.60921706167 0.6153957979333352 0.5140053329536526 0.7187363724125034 0.45392329040668716 0.7688980791449698 0.8765556674548097 1.061155887789128 1.175075955214882 0.9654330812820333 1.0 15.102082704754963 -6.791913011430973 1.7651332772058035 1.0639119269394042 0.5814308897215782 0.8496000587849356 0.08869845347972208 0.1192613261430572 0.7678059591978015 0.03599374715184821 0.0321259499715148 1.6146819429425566e-07 6.791913011430973 -0.482481037217826 T(ph)PSASNDDQQE ddPTM_PC-9_Lapatinib_30min_R1 2 TPSASNDDQQE 11 0 O43765 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 T(0.645)PS(0.287)AS(0.068)NDDQQE;T(0.776)PS(0.112)AS(0.112)NDDQQE 130.1 0.00055323 8968400.0 16449.1 12484.0 15082.8 11951.8 16530.0 20323.7 18973.8 17676.5 20304.0 16567.4 True False 16214.53281760449 12455.09406501468 13842.750405291696 12830.775242036016 15557.737899230391 19454.502727858664 19956.170524483598 18497.814721235856 18017.149709401354 19431.053015327132 0.8344649569333445 0.6409891453227036 0.7124035117588632 0.660323206977777 0.8006636535322359 1.0012068163528263 1.0270246552640383 0.951971810619057 0.9272348593351839 1.0 14.246076465692763 -6.618170416139877 3.6416613911434323 0.981320880241378 0.7083912593882917 0.8446481216178546 0.05490101068317482 0.0849288249982199 2.1893025385147236 0.01876644787045662 0.018819613087608437 2.40895997293708e-07 6.618170416139877 -0.27292962085308625 T(ph)PSEAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSEAER 7 0 A0A0C4DGH3;Q9Y6R0 A0A0C4DGH3 NUMBL Numb-like protein 1 T(0.996)PS(0.004)EAER 107.01 0.024380000000000002 32480000.0 31436.0 36551.0 42970.0 34725.0 47534.0 32656.0 36242.0 29145.0 35371.0 37298.0 True False 36757.49391069834 40179.54172285634 43994.56776463249 32779.47082996897 38220.05392567409 30943.46187239753 32808.895390642276 28379.974631680063 35888.23395964231 44059.83214919446 0.8342631398646935 0.9119313388848427 0.998518732791787 0.743976298388333 0.8674580011166216 0.7023054869482354 0.7446441302714341 0.6441235303752497 0.8145340599146711 1.0 15.42717637849233 -5.7759585038995835 24.999042349864553 0.7712356354660862 0.9146071083600726 0.24215060712822223 0.09966401988666407 273.1605992994981 470327.5926243771 0.027176292224010468 0.04050970816203194 1.6751029216205052e-06 5.7759585038995835 0.14337147289398644 T(ph)PSFELPDASERPPTYCELVPR ddPTM_PC-9_AZD4547_30min_R2 2 TPSFELPDASERPPTYCELVPR 22 1 Q9BRG2;Q9BRG2-2 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 T(0.721)PS(0.255)FELPDAS(0.007)ERPPT(0.009)Y(0.008)CELVPR;T(0.47)PS(0.47)FELPDAS(0.049)ERPPT(0.006)Y(0.006)CELVPR 49.593 0.029685000000000003 60503000.0 0.0 0.0 2661.4 0.0 1763.0 5889.8 0.0 3194.3 0.0 0.0 True False 0.0 0.0 2626.1080970721323 0.0 1518.2378815951556 5521.509874922881 0.0 2700.6943327116755 0.0 0.0 0.0 T(ph)PSFELPDASERPPTYCELVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPSFELPDASERPPTYCELVPR 22 1 Q9BRG2;Q9BRG2-2 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 T(0.644)PS(0.349)FELPDAS(0.007)ERPPTYCELVPR;T(0.346)PS(0.346)FELPDAS(0.299)ERPPT(0.005)Y(0.004)CELVPR 61.806999999999995 0.0042306 40263000.0 11892.0 18311.4 13019.0 14419.32 17150.9 11539.26 18442.2 14721.7 11977.0 11567.46 True False 13905.080722293691 20129.23477617333 13329.422334832454 13611.452248466174 13790.30426376581 10934.120891893746 16695.22130603453 14335.270973930505 12152.140966742123 13664.54893003702 1.0176026148750466 1.4730991033246492 0.9754747414700312 0.9961142748404865 1.0092030358537747 0.8001816194502165 1.2217908832201239 1.0490848287292618 0.8893188519402667 1.0 13.738150216495137 -5.302840241258901 24.977993812726478 0.996424215827436 1.245351078734416 0.3292715933549829 0.14418724402919103 467.8308531489149 282251.156497431 0.03606642305563461 0.07507940915317897 4.979202152761071e-06 5.302840241258901 0.24892686290697996 T(ph)PSFELPDASERPPTYCELVPR ddPTM_PC-9_Lapatinib_30min_R1 2 TPSFELPDASERPPTYCELVPR 22 1 Q9BRG2;Q9BRG2-2 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 T(0.778)PS(0.222)FELPDASERPPTYCELVPR;T(0.71)PS(0.269)FELPDAS(0.011)ERPPT(0.006)Y(0.005)CELVPR 83.115 0.0002144 49856000.0 3564.8 2067.0 4982.5 3150.9 5905.8 10790.0 4660.3 5946.6 3818.1 9520.7 True False 3513.965298295745 2062.2139884961016 4572.8580830061965 3382.6276970942677 5558.432455249536 10328.536852718507 4901.587530976972 6222.900745130608 3388.0653716245697 11166.340309464678 0.3146926567621515 0.1846812770651592 0.4095216477622669 0.30293073678106747 0.4977846188816371 0.924970631959332 0.43896096618355324 0.5572909809900768 0.3034177069413529 1.0 13.446868809551184 -6.38509662399918 4.077234515508969 0.6133127976079229 0.3024794117720591 0.3836314640939319 0.20117538430106097 0.2725843556030126 7.70307695510051 0.06340461932028685 0.07225062436828862 4.120058437875469e-07 6.38509662399918 -0.3108333858358638 T(ph)PSGEFLER ddPTM_PC-9_AZD4547_30min_R2 1 TPSGEFLER 9 0 B3KT28;B1ANM7;Q9UNN5-2;Q9UNN5 B3KT28 FAF1 FAS-associated factor 1 1 T(0.912)PS(0.088)GEFLER 96.171 0.012691 3704200.0 17019.0 14830.0 25275.0 25231.0 25529.0 26838.0 24773.0 26086.0 18703.0 24077.0 True False 22430.687982808962 19623.507483543795 24939.83698560839 19414.382765064114 21984.739012616414 25159.815617369055 26977.749008339964 22055.00809664615 19691.602397068735 23234.071558468437 0.9654221786466585 0.8446004581745962 1.073416552189202 0.8355996802457937 0.9462284282499482 1.0828844851430577 1.1611287733383526 0.9492528264426155 0.8475312795484384 1.0 14.503954374957347 -6.550305121588154 21.40825641935826 1.0145495372022078 0.9285601239686533 0.12749248769063615 0.09826426152608478 90.63230256471077 70742.51168452599 0.03364922016769411 0.03365164022075122 2.8164035198376596e-07 6.550305121588154 -0.08598941323355447 T(ph)PSGEFLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSGEFLER 9 0 B3KT28;B1ANM7;Q9UNN5-2;Q9UNN5 B3KT28 FAF1 FAS-associated factor 1 1 T(0.777)PS(0.223)GEFLER 98.04 0.011223 5886900.0 7315.2 6840.0 12799.0 8096.5 12134.0 7027.2 9941.3 10456.0 7055.2 7095.2 True False 8553.518878214165 7519.029996014815 13104.176700477807 7642.87935420716 9756.42980464782 6658.681261321413 8999.588095220795 10181.541079047753 7158.368952872924 8381.503594427704 1.0205232010997194 0.8970979862149925 1.563463709445867 0.9118744946060029 1.164042906470172 0.794449490631767 1.0737438687258947 1.2147630749471696 0.8540673964074942 1.0 13.03299336314985 T(ph)PSIDLQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPSIDLQR 8 0 A0A0U1RR27;Q7Z401;Q7Z401-2 A0A0U1RR27 DENND4A C-myc promoter-binding protein 1 T(0.993)PS(0.007)IDLQR;T(0.947)PS(0.053)IDLQR 120.99 0.0082932 8889800.0 24151.0 31571.0 40479.0 38988.0 47617.0 49047.0 47613.0 36800.0 40113.0 36457.0 True False 28239.28729600699 34705.16023452975 41444.17287746237 36803.62876080147 38286.79067149461 46474.88897769116 43102.751951731465 35834.03899282301 40699.57673865966 43066.36550654678 0.6557155906670175 0.8058530091018247 0.9623327250859417 0.8545793992113573 0.8890183840954584 1.079145835295208 1.0008448924063293 0.8320655474717423 0.9450432201545466 1.0 15.394273955115978 -4.1494815159437985 0.9087670598630487 0.9502750111366717 4.415857177400399e-10 0.6319565627218384 0.07008340675112829 4.10705202833812 1.1819358117358865 0.02515129459495326 5.088895719317282 7.087914727626686e-05 4.1494815159437985 -0.9502750106950859 T(ph)PSIQPSLLPHAAPFAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSIQPSLLPHAAPFAK 17 0 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;H0YF36 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 T(0.499)PS(0.499)IQPS(0.001)LLPHAAPFAK 88.471 0.005704 31926000.0 32974.0 26923.0 38902.0 53220.0 70665.0 55523.0 46841.0 61796.0 52037.0 37449.0 True False 38555.846933813686 29595.737512091648 39829.57121665657 50238.25594156802 56818.70052294697 52611.27613734466 42403.88138052746 60173.92047827419 52797.942680667955 44238.2072538791 0.871550845461371 0.6690085188634423 0.9003432482713016 1.135630466516312 1.2843807208748208 1.1892723372674951 0.9585352574794768 1.3602251133944343 1.1934919147529035 1.0 15.433005301325869 -5.672322055934008 3.1148223416031997 1.1761390195151276 0.7714357791799219 0.6412412749124277 0.12103903566517633 0.14290121028630437 2.7595275937165464 0.03386723485991596 0.0630367371052931 2.126561485654473e-06 5.672322055934008 -0.40470324033520566 T(ph)PSNELYKPLR ddPTM_PC-9_Lapatinib_30min_R1 2 TPSNELYKPLR 11 1 Q8WUM4;Q8WUM4-2 Q8WUM4 PDCD6IP Programmed cell death 6-interacting protein 1 T(0.851)PS(0.149)NELYKPLR;T(0.987)PS(0.012)NELYKPLR 64.73 0.03349 11285000.0 31834.0 41578.0 42169.0 30856.0 41009.0 46074.0 39807.0 44567.0 40034.0 34564.0 True False 31380.041322359368 41481.72869554468 38702.02759704731 33125.253172598554 38596.9312467961 44103.52242373979 41868.01168285312 46637.74551983244 35524.94934329067 40538.341346364956 0.7740830108031342 1.0232714836830472 0.9547018035684307 0.8171339051485113 0.9521092862931615 1.08794590402487 1.0328003142784576 1.1504601315913092 0.8763296218698441 1.0 15.306999440719151 -6.570664469474596 6.148222111368754 1.0381178802046915 0.9034548091261378 0.328922504211134 0.09164039544058677 0.22739204088736045 20.066298395304543 0.029504649099028297 0.0296869850792286 2.6874199110776375e-07 6.570664469474596 -0.1346630710785537 T(ph)PSPESHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSPESHR 8 0 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 T(0.816)PS(0.183)PES(0.001)HR 94.309 0.01656 4013800.0 31331.0 29082.0 23173.0 34986.0 39359.0 36169.0 31340.0 27367.0 36054.0 31682.0 True False 36634.71948454288 31969.068763757692 23725.532204091898 33025.847846142395 31646.886490945595 34272.23396811449 28371.248318048918 26648.64524773334 36581.221542533225 37425.69580542599 0.9788654211001087 0.854201052933338 0.6339369701351595 0.8824377779865965 0.8455924682195867 0.915740729211658 0.7580686933797941 0.7120414109674298 0.9774359769479468 1.0 15.191741518163294 -8.39120381437408 7.024228937918636 0.9983597987098595 0.8213076396100464 0.32924605511344307 0.0950121118752695 0.29802560949553164 14.93344441631991 0.0934707351123481 0.024191015555267672 4.062526300864605e-09 8.39120381437408 -0.1770521590998131 T(ph)PSPGPVESK ddPTM_PC-9_AZD4547_30min_R2 1 TPSPGPVESK 10 0 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 T(0.528)PS(0.472)PGPVESK 90.913 0.020555 14520000.0 37133.0 42386.0 48866.0 67659.0 70096.0 57803.0 47818.0 70078.0 53884.0 59577.0 True False 48940.521585618735 56086.445596593876 48218.00491152281 52061.26287112971 60364.38034503351 54188.569272329616 52073.7093642595 59249.055332238364 56732.198233633746 57491.227363827464 0.851269381951155 0.9755652847982603 0.8387019571939212 0.9055514251185703 1.0499755025757858 0.942553703531196 0.905767918898587 1.0305755860330945 0.9867974791111994 1.0 15.811054210314884 -6.085903245224472 9.292498632111167 0.9811631875846004 0.8930756747088606 0.4427098231438149 0.05123327977846438 0.4191008837502739 42.76072834230718 0.015060085460360872 0.019475785619814393 8.205343276141634e-07 6.085903245224472 -0.08808751287573979 T(ph)PSPNSNEQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSPNSNEQQK 11 0 Q9H4E7 Q9H4E7 DEF6 Differentially expressed in FDCP 6 homolog 1 T(0.98)PS(0.02)PNS(0.001)NEQQK 104.2 0.0044291 0.0 5214.6 4304.9 4933.6 3567.6 6390.0 6207.5 6495.8 4800.7 4682.0 3365.6 True False 6097.328786955326 4732.262021907042 5051.23573478219 3367.718938315257 5137.925370998813 5881.967772320792 5880.470798480612 4674.686711762103 4750.465392526226 3975.756637925057 1.5336272670194209 1.1902796003069254 1.270509287866881 0.8470636522845286 1.2923138509001624 1.4794587063534614 1.4790821808322814 1.1757980021135843 1.1948581930823334 1.0 11.957013734720224 -8.601266076787212 1.8154796215343525 1.0034311189875693 1.2800775809378286 0.1787384505432208 0.1867413946394634 0.8723782072302794 6.316183450455506 0.1902958631629978 0.05382342345502071 2.5045743192481263e-09 8.601266076787212 0.2766464619502593 T(ph)PSPPPPIPEDIALGK ddPTM_PC-9_Lapatinib_30min_R1 1 TPSPPPPIPEDIALGK 16 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 T(0.592)PS(0.408)PPPPIPEDIALGK 102.63 0.0036066 2150000.0 3477.2 4411.6 4825.7 4118.5 6030.3 5005.5 4681.3 4320.7 5848.6 4433.0 True False 3427.6144903596146 4401.385211247895 4428.94957374069 4421.388228913248 5675.609610025959 4791.426433390403 4923.674808223183 4521.4554954908335 5189.869079511658 5199.238143398793 0.6592532205341434 0.8465442608810118 0.8518458765663389 0.8503915587184362 1.091623321242169 0.9215631793042279 0.9469992857462245 0.869638083654909 0.9981979929311315 1.0 12.344084521903257 -3.9815372504063102 0.6986278065767211 0.9575294323167945 1.5935179431432544e-19 0.6599462819346436 0.06530776610557981 5.205320296669401 0.8497291654018561 0.026889390098865668 5.101009104360015 0.00010434286316894508 3.9815372504063102 -0.9575294323167945 T(ph)PSPSPPCSSSPSPSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSPSPPCSSSPSPSGR 17 0 O75385 O75385 ULK1 Serine/threonine-protein kinase ULK1 1 T(0.866)PS(0.124)PS(0.01)PPCSSSPSPSGR 125.39 5.3228e-05 0.0 6111.1 9755.6 13236.0 10258.0 12436.0 11220.0 7618.0 7983.3 7631.9 9010.7 True False 7145.588530273209 10724.071495485692 13551.596437809527 9683.27751688471 9999.255072572956 10631.603448318849 6896.367890456179 7773.746834005538 7743.502099363712 10644.26858133805 0.6713085521724935 1.007497266114419 1.2731355221126905 0.909717510685686 0.9394027401848957 0.9988101452981554 0.6478949528337872 0.730322311448884 0.7274809011245661 1.0 13.377789198261217 -7.2469757741230065 24.176397765815743 0.7539514009803545 0.9786076654524588 0.24286696698397403 0.16178750154785293 652.5320235030508 1090730.2542139594 0.0626946116700751 0.04831419216043025 5.662708759603617e-08 7.2469757741230065 0.2246562644721043 T(ph)PSPSQPK ddPTM_PC-9_AZD4547_30min_R2 1 TPSPSQPK 8 0 Q9NTI5-2;Q9NTI5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 T(0.83)PS(0.085)PS(0.085)QPK 104.2 0.0094428 5108100.0 28658.0 26131.0 36151.0 46349.0 34679.0 29653.0 24159.0 39508.0 32396.0 39767.0 True False 37770.64787656967 34577.334730443916 35671.61411935623 35663.954134911706 29864.419453113118 27798.793222365457 26309.104197815563 33402.94640352281 34108.386422255215 38374.76943413278 0.9842573241097894 0.9010434522556062 0.9295590473991954 0.9293594374847262 0.7782305898768461 0.724402872832366 0.6855833816271661 0.8704403152403636 0.8888232274802206 1.0 15.22787046196106 -6.251692371037998 22.68837996641607 0.8061433875580591 0.9330900602475453 0.27214091623424497 0.08614943458419554 239.50345524215166 557495.4887018818 0.026092240853000652 0.033178217838664585 5.60154241698712e-07 6.251692371037998 0.12694667268948612 T(ph)PSPTPQPTSPQR ddPTM_PC-9_AZD4547_30min_R2 1 TPSPTPQPTSPQR 13 0 H7C1I9;O15021-2;O15021-3;O15021-6;O15021 H7C1I9 MAST4 Microtubule-associated serine/threonine-protein kinase 4 1 T(0.851)PS(0.149)PTPQPTSPQR 126.09 0.00073165 0.0 4646.9 3357.5 4836.7 6256.6 4476.9 3406.6 3864.8 4599.2 3032.9 3783.6 True False 6124.5175384755275 4442.74621550899 4772.56219775636 4814.23753350641 3855.359711919087 3193.58476347453 4208.759712890335 3888.4993191020058 3193.212902211934 3651.1373156382087 1.6774273353794635 1.216811593604063 1.3071439897138266 1.3185583332860473 1.0559339128129124 0.8746821845883658 1.1527256712213398 1.0650104290647056 0.8745803365255708 1.0 11.834130212778893 -1.5228787452803503 0.35256332644488036 0.96788762686336 8.6016679978144 0.7392767473060384 0.11708478362001191 33.68246260557763 0.47319520426147266 0.10173055963032367 171.34374041457826 0.02999999999999912 1.5228787452803503 7.63378037095104 T(ph)PSPTPQPTSPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSPTPQPTSPQR 13 0 H7C1I9;O15021-2;O15021-3;O15021-6;O15021 H7C1I9 MAST4 Microtubule-associated serine/threonine-protein kinase 4 1 T(0.54)PS(0.447)PT(0.013)PQPTSPQR 92.538 0.013222 0.0 4271.8 5710.6 4317.4 4864.8 6002.3 4892.5 5092.8 3384.4 3310.9 2544.6 True False 4994.931368104122 6277.5106279593865 4420.343189830679 4592.241027894399 4826.192402871077 4635.928687245984 4610.373115320982 3295.5630860682127 3359.315648892585 3005.9158369574848 1.6617003399402794 2.0883853602213063 1.47054788942622 1.527734400089709 1.6055647145982745 1.5422682931596512 1.5337665341912865 1.096359068191311 1.117568099409198 1.0 11.553588900269027 -7.473731548456102 0.48125800076660685 0.9429760351973597 1.7987021206099838 0.7173602762505404 0.16252419992091977 0.5248648036654746 0.27456787512398284 0.1708139790254701 0.14166481945254697 3.3594520873541396e-08 7.473731548456102 0.8557260854126241 T(ph)PSSDVLVFDYTK ddPTM_PC-9_AZD4547_30min_R2 1 TPSSDVLVFDYTK 13 0 Q09028-3;Q09028;Q09028-4;Q09028-2;H0YF10;E9PC52;Q16576;Q16576-2;Q5JP01 Q09028-3;E9PC52 RBBP4;RBBP7 Histone-binding protein RBBP4;Histone-binding protein RBBP7 1 T(0.699)PS(0.196)S(0.105)DVLVFDYTK 111.83 0.0012772999999999999 2330000.0 6179.2 8612.0 8393.1 9754.7 9217.4 10639.0 8401.0 8813.7 8118.8 7543.5 True False 8144.057064655566 11395.660583161105 8281.802010045882 7505.904623612657 7937.723113905384 9973.741648155203 9148.672725106531 7451.745183677462 8547.943193141302 7279.4043610626995 1.11878069423068 1.565466076333955 1.137703251428781 1.0311152192288562 1.0904357994404061 1.3701315593215877 1.256788642494225 1.023675126983824 1.1742640976044656 1.0 12.829604691061705 -1.6811654882665654 0.024127718469263242 1.915047217107485e-06 2.765719902692927 0.15791577404399593 0.15440726224749818 3901.12450514436 7.454107223529317 300.53807582803694 601.666888131442 0.020836967374605813 1.6811654882665654 2.7657179876457096 T(ph)PSSDVLVFDYTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSSDVLVFDYTK 13 0 Q09028-3;Q09028;Q09028-4;Q09028-2;H0YF10;E9PC52;Q16576;Q16576-2;Q5JP01 Q09028-3;E9PC52 RBBP4;RBBP7 Histone-binding protein RBBP4;Histone-binding protein RBBP7 1 T(0.984)PS(0.015)S(0.001)DVLVFDYTK 84.29700000000001 0.021168 2427300.0 7082.7 6922.7 9844.3 9326.8 10572.0 8274.0 11640.0 8829.9 7491.8 7654.4 True False 8281.661220298489 7609.939905469551 10079.025446715654 8804.24963389358 8500.492491737006 7840.096874455455 10537.37493369782 8598.124481052391 7601.353401906873 9042.082127802942 0.9159020127492228 0.8416136679482501 1.1146797058748537 0.9736971539798267 0.940103437636268 0.8670676469912194 1.1653704074747446 0.9509009495295943 0.8406640522025275 1.0 13.14243930614954 -5.196722793170668 24.999941365728915 0.9805223872148313 0.8787577338388863 0.15766068941700795 0.09502413458472414 388.9114107596991 150233.72503259525 0.02425475395464301 0.0641720360598291 6.357365881515659e-06 5.196722793170668 -0.10176465337594498 T(ph)PSSDVLVFDYTK ddPTM_PC-9_Lapatinib_30min_R1 2 TPSSDVLVFDYTK 13 0 Q09028-3;Q09028;Q09028-4;Q09028-2;H0YF10;E9PC52;Q16576;Q16576-2;Q5JP01 Q09028-3;E9PC52 RBBP4;RBBP7 Histone-binding protein RBBP4;Histone-binding protein RBBP7 1 T(0.832)PS(0.164)S(0.003)DVLVFDYTK;T(0.761)PS(0.225)S(0.014)DVLVFDYTK 110.44 0.0016537 4331200.0 28391.0 29978.0 35071.0 33371.0 39312.0 42789.0 40786.0 39613.0 40458.0 38874.0 True False 27986.139133728262 29908.587782842827 32187.59775797495 35825.2146623926 36999.74545036571 40959.01421603078 42897.69951256931 41453.56459436628 35901.19399837275 45593.31910365098 0.6138210528192761 0.6559861920745277 0.7059718044391609 0.7857557941975718 0.8115168225908537 0.898355614841625 0.9408768731016598 0.9092026070777286 0.7874222518600952 1.0 15.476534817926908 -5.8414976098701965 0.8103516596276396 0.90982989050198 0.5969821133610772 0.8201667846200428 0.051063925899406545 0.3413115771445789 0.41684180548960537 0.02422983397354282 0.07375334837521248 1.4404639377850818e-06 5.8414976098701965 -0.31284777714090284 T(ph)PSSEEISPTK ddPTM_PC-9_AZD4547_30min_R2 2 TPSSEEISPTK 11 0 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 T(0.586)PS(0.406)S(0.008)EEISPTK;T(0.872)PS(0.102)S(0.026)EEISPTK 145.14 0.00033649 53202700.0 63938.0 78550.0 83967.0 79164.0 68508.0 82381.0 80984.0 96749.0 74504.0 81335.0 True False 84268.95400698263 103939.75137102937 82853.54271693683 60913.9628716078 58996.8467341582 77229.70304696615 88191.41911320404 81798.66512084713 78442.12933706936 78487.48640644709 1.0736610110125866 1.3242843685014685 1.055627419228081 0.7760977661606479 0.7516720108558873 0.983974727474804 1.1236366859362164 1.0421873456012225 0.9994221108172219 1.0 16.26017503688565 -5.517436477822454 24.988051880153012 0.9524679888469543 1.1967185224975907 0.395902760536299 0.12068414083893729 237.66740270176757 1091243.2189098524 0.03605257417603288 0.06495386754434952 3.0378303883800786e-06 5.517436477822454 0.24425053365063643 T(ph)PSSEEISPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPSSEEISPTK 11 0 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 T(0.889)PS(0.108)S(0.003)EEISPTK;T(0.384)PS(0.308)S(0.308)EEISPTK 153.34 0.00016376 45155800.0 61323.0 91049.0 76299.0 76010.0 88313.0 48689.0 79663.0 52669.0 50668.0 46688.0 True False 71703.7727155412 100087.74299812151 78118.25752556903 71751.40612774475 71008.70161017512 46135.66312791411 72116.74392982564 51286.49455741838 51408.92364556152 55152.16481799536 1.3001080365959685 1.8147563804324922 1.4164132592684768 1.3009717091709387 1.2875052474278579 0.8365159061328578 1.3075958879912357 0.9299090022425436 0.9321288441752611 1.0 15.751129894756689 -6.176727097170902 1.1877001057087422 1.010121424467154 1.5614944373991564 0.605117274973177 0.17543990391585362 0.30896596842339435 0.8933104450006659 0.06838393390943914 0.10939440958815183 6.656913332426451e-07 6.176727097170902 0.5513730129320025 T(ph)PSSEEISPTKFPGLYR ddPTM_PC-9_AZD4547_30min_R2 1 TPSSEEISPTKFPGLYR 17 1 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 T(0.406)PS(0.187)S(0.406)EEISPTKFPGLYR 146.1 0.00096771 23241000.0 47976.0 55078.0 68973.0 84830.0 75722.0 70232.0 65427.0 80261.0 46656.0 69056.0 True False 63231.370037207984 72880.88639100647 68058.37295384244 65273.75411043508 65209.307356862424 65840.38193751629 71249.87625110634 67858.50666429936 49122.140909888185 66638.3704590105 0.9488732932943164 1.0936774997497238 1.0213090819155817 0.9795220630520249 0.9785549512644955 0.988025089509278 1.0692019591765436 1.0183098145540543 0.7371449897638687 1.0 16.02406550174978 -8.214420983018888 24.94807987300432 0.8685723719274879 1.014090437507225 0.39087908444730424 0.07167851721060886 317.0478204390296 168226.8050369903 0.04502764361129691 0.0170187078019753 6.1035009566743055e-09 8.214420983018888 0.14551806557973712 T(ph)PSSEEISPTKFPGLYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSSEEISPTKFPGLYR 17 1 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 T(0.661)PS(0.174)S(0.164)EEISPTKFPGLYR 65.92399999999999 0.015013 41897000.0 65268.0 63796.0 61680.0 91335.0 91669.0 89040.0 72748.0 77276.0 79960.0 67281.0 True False 76316.58329823958 70129.24526692415 63150.68512270262 86217.79606206545 73707.11750142247 84370.58565403837 65856.78279009007 75247.58688068992 81129.26373054206 79478.51270389718 0.9602165503846606 0.8823673579322704 0.794562995384362 1.084793777951985 0.9273842073017087 1.0615521451485503 0.8286111623080338 0.9467664192588773 1.020769777522069 1.0 16.278277254970597 -5.751607056607118 24.999989006124874 0.9739144406358834 0.8793808464132215 0.2628539576227873 0.07784795169095607 304.3580019262578 773862.9190379367 0.02106858030887803 0.035925253921321815 1.7717112521681778e-06 5.751607056607118 -0.09453359422266194 T(ph)PSSPCPASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TPSSPCPASK 10 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 T(0.971)PS(0.028)SPCPASK;T(0.949)PS(0.048)S(0.003)PCPASK;T(0.869)PS(0.021)S(0.108)PCPAS(0.002)K 108.7 0.004867100000000001 88176100.0 312251.0 329242.0 359439.0 372295.0 392176.0 350080.0 371731.0 332191.0 326481.0 287363.0 True False 365108.9270616317 361926.96987542487 368009.38893999765 351436.51814667485 315331.9280589724 331721.18851938174 336517.9485806213 323471.3382354592 331255.16698362987 339459.6371357431 1.075559174405268 1.0661855793202817 1.0841035241925923 1.0352821947021125 0.9289231872149721 0.9772036266766322 0.9913342022635065 0.9529007364905344 0.975830793253242 1.0 18.372880517932124 -6.044865531804273 4.6981541346240805 0.9702438990631118 1.0729615930009004 0.8599952991470416 0.01911378189443766 0.06888565427251671 3.4335323152085793 0.005572785183640168 0.007573028438598922 9.018503293053199e-07 6.044865531804273 0.10271769393778862 T(ph)PSSSSTLAYSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPSSSSTLAYSPR 13 0 A0A087WUB0;H3BR17;Q6Q0C0 A0A087WUB0 TRAF7 E3 ubiquitin-protein ligase TRAF7 1 T(0.573)PS(0.418)S(0.009)S(0.001)STLAYSPR;T(0.504)PS(0.475)S(0.014)S(0.006)S(0.001)T(0.001)LAYSPR 156.52 0.00050954 31635000.0 59672.0 71505.0 69625.0 54618.0 74353.0 46361.0 67016.0 51096.0 57668.0 52688.0 True False 69773.29102427754 78603.54383991807 71285.1240542828 51557.930533945146 59784.06339747653 43929.74754612393 60667.759326176325 49754.78414068711 58511.28540286256 62239.917322021494 1.121037655999434 1.2629120863582326 1.1453280647122737 0.8283740202801188 0.9605421403142507 0.7058130768207315 0.9747403585433602 0.7994031207217407 0.9400925952412909 1.0 15.925552523434146 -5.696515307672916 5.394166845838663 0.8778571440585415 1.192667041407554 0.6760140618314315 0.09179198293891888 0.10081545856613496 5.580483403114214 0.02329414031303538 0.04051985605417916 2.0113363029393967e-06 5.696515307672916 0.31480989734901244 T(ph)PSTSDMAEEGR ddPTM_PC-9_Lapatinib_30min_R1 1 TPSTSDMAEEGR 12 0 Q9HCH0 Q9HCH0 NCKAP5L Nck-associated protein 5-like 1 T(0.792)PS(0.154)T(0.023)S(0.032)DMAEEGR 95.273 0.010102 0.0 4534.2 2076.2 3861.1 3827.0 5149.7 4592.6 5558.9 7375.5 7936.9 6344.7 True False 4469.541476529554 2071.392686461348 3543.655262277015 4108.450346497755 4846.804770699746 4396.185203873493 5846.712642093405 7718.192655586513 7042.96274273777 7441.372941218665 0.6006339840558484 0.2783616279984643 0.47620987286476124 0.552109184548533 0.6513320604928572 0.5907760891169009 0.7857034835208643 1.0372000861339055 0.9464601221269192 1.0 12.861353109322337 -7.223309023665171 0.8223148897059362 1.035152817051329 0.44957203771127785 0.8386966669617134 0.09376365671539613 0.23416810376374994 0.3121127818888918 0.07508037303695812 0.04638265779904614 5.979859447785768e-08 7.223309023665171 -0.5855807793400513 T(ph)PSVSAPLALSCPR ddPTM_PC-9_AZD4547_30min_R2 1 TPSVSAPLALSCPR 14 0 C9JRJ5;Q9UGP4 C9JRJ5 LIMD1 LIM domain-containing protein 1 1 T(0.987)PS(0.013)VSAPLALSCPR 82.925 0.027699 0.0 25018.0 30703.0 31357.0 26978.0 28743.0 37244.0 27788.0 33161.0 30173.0 31638.0 True False 32973.20359327308 40627.14432011096 30941.185691700168 20758.638905945056 24752.530590294686 34915.12679235759 30261.078167511034 28036.72941397234 31767.883180599645 30530.36324985772 1.0800134712916245 1.3307127723185637 1.0134561923970675 0.6799342260050507 0.8107512638392875 1.1436197632702683 0.9911797615985476 0.9183228245442838 1.040534071626144 1.0 14.897957134362754 -5.507797530476645 24.483454280434472 0.9350111582051227 1.1970435451519645 0.3843082846455309 0.13205220959874306 527.9136040725496 857034.2723872586 0.036819952560312674 0.07267519237403101 3.106007281506331e-06 5.507797530476645 0.26203238694684183 T(ph)PSYSISSTLNPQAPEFILGCTASK ddPTM_PC-9_AZD4547_30min_R2 1 TPSYSISSTLNPQAPEFILGCTASK 25 0 Q14694;Q14694-3;Q14694-2;H3BQC6 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 T(0.9)PS(0.087)Y(0.002)S(0.005)IS(0.005)S(0.001)T(0.001)LNPQAPEFILGCTASK 103.85 1.6475e-06 8626200.0 15618.0 17719.0 26098.0 27857.0 26622.0 30218.0 29428.0 31445.0 25619.0 26286.0 True False 20584.19912541926 23446.320236069623 25751.923467869718 21434.999036359688 22925.99482916973 28328.463683048587 32047.034990410066 26585.89778421523 26973.168037774893 25365.73514083572 0.8114962571016215 0.9243304050086025 1.0152248032587978 0.84503756415291 0.9038174806241547 1.1168004209522489 1.2633986286018681 1.0481027905008438 1.0633702468315773 1.0 14.630593352305873 -6.760720352845843 24.963809363512087 1.1116573803840453 0.9046839900490284 0.5933095093854086 0.08169315592495054 13.391895430417765 464959.03019942855 0.028447341999378442 0.026862747715346393 1.7349207733726442e-07 6.760720352845843 -0.20697339033501683 T(ph)PSYSISSTLNPQAPEFILGCTASK ddPTM_PC-9_Lapatinib_30min_R1 1 TPSYSISSTLNPQAPEFILGCTASK 25 0 Q14694;Q14694-3;Q14694-2;H3BQC6 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 T(0.703)PS(0.186)Y(0.021)S(0.014)IS(0.051)S(0.012)T(0.012)LNPQAPEFILGCTASK 90.71 1.188e-05 6154500.0 15461.0 15225.0 19411.0 14600.0 22597.0 28471.0 28049.0 23948.0 25307.0 23295.0 True False 15240.523304799854 15189.74744792122 17815.102508626835 15673.732704172238 21267.888887411318 27253.361699142595 29501.23997518896 25060.711506472217 22456.659165475765 27321.509711363615 0.5578214185748669 0.5559629613587375 0.6520541030431105 0.5736774017891547 0.7784302226375703 0.9975057010779798 1.0797807400415633 0.917252076156279 0.8219406395443641 1.0 14.737749584733812 -6.5026215886913965 2.8748780511020917 0.9648916607154979 0.5875208708893145 0.8727703035418528 0.06794644330655247 0.09628410861656979 1.6063316773779541 0.025241804612758607 0.027274009476632763 3.1432462877142364e-07 6.5026215886913965 -0.37737078982618344 T(ph)PT(ph)PPPR ddPTM_PC-9_AZD4547_30min_R2 1 TPTPPPR 7 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 2 T(1)PT(1)PPPR 91.087 0.025973000000000003 0.0 31498.0 33272.0 43543.0 37508.0 34309.0 47332.0 35974.0 56007.0 40598.0 43033.0 True False 41513.70880089996 44026.523330577824 42965.59136950922 28861.11009282329 29545.78756644822 44372.32255761653 39175.61630912774 47352.40506282532 42743.92739754031 41526.42776822577 0.9996937139067971 1.0602049272406961 1.0346565712157074 0.6950058467322964 0.7114935994820961 1.0685321358551414 0.9433899907736161 1.1402956528578974 1.0293186699349595 1.0 15.341742151559561 -7.640111007222344 6.697595277816851 1.0630412163130643 0.9257368749883984 0.16719294628625425 0.1288817873959609 0.41261424945102443 22.462758507406004 0.0682532046242288 0.03895864412086872 2.2902821736334634e-08 7.640111007222344 -0.13730434132466585 T(ph)PT(ph)PPPR ddPTM_PC-9_Lapatinib_30min_R1 2 TPTPPPR 7 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 2 T(1)PT(1)PPPR;T(1)PT(1)PPPR 91.087 0.025973000000000003 0.0 90761.0 108819.0 105832.0 93285.0 102367.0 97627.0 81642.0 83910.0 108824.0 83120.0 True False 89466.73149647097 108567.03629131953 97130.90148333398 100145.49008963774 96345.97432126552 93451.72078965249 85869.02328262609 87808.76492851526 96567.09515247702 97487.18124956173 0.9177281602536146 1.1136544815404394 0.9963453680611023 1.027268291133281 0.9882937744873883 0.9586052195972444 0.8808237368439876 0.9007211389539486 0.9905619786592317 1.0 16.572924908529565 -6.692189859997575 2.4780387258355305 0.9338178331371727 1.018985076742585 0.23527838780790156 0.056222104787006844 0.34008289324379 4.267629626379789 0.02019301981206199 0.019490231110232802 2.0314687220404706e-07 6.692189859997575 0.08516724360541228 T(ph)PTAPAVNLAGAR ddPTM_PC-9_AZD4547_30min_R2 3 TPTAPAVNLAGAR 13 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(0.999)PT(0.001)APAVNLAGAR;T(0.999)PT(0.001)APAVNLAGAR;T(0.999)PT(0.001)APAVNLAGAR 113.53 0.00081896 55867000.0 9037.4 15546.0 14453.2 18042.2 16556.7 20362.1 10225.599999999999 20197.5 15076.0 13838.3 True False 11911.10521040236 20570.940481400663 14261.541124446892 13882.849539211284 14258.087994444983 19088.854668098607 11135.658590387966 17076.440467377543 15872.886581735993 13353.825329050696 0.8919620346156724 1.5404530143620667 1.0679742151053524 1.039615930051872 1.0677156277779896 1.4294671524998601 0.8338927847260964 1.2787676973899345 1.1886396736974822 1.0 13.704965454250443 -10.89689945673169 3.6249409924407034 0.9991737843260445 1.1550985533303668 0.04241272046818201 0.2100409218285814 66200231.84308546 554.748063744739 461128.780022252 0.04909499509626167 1.2679453731933243e-11 10.89689945673169 0.15592476900432228 T(ph)PTAPAVNLAGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TPTAPAVNLAGAR 13 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(0.999)PT(0.001)APAVNLAGAR;T(1)PTAPAVNLAGAR;T(0.998)PT(0.002)APAVNLAGAR 133.04 0.00011927 37825100.0 11484.5 20852.1 9413.9 5834.5 11669.7 13185.7 14091.400000000001 4280.6 9339.8 10095.4 True False 13428.599020785568 22922.158681271994 9638.363078414566 5507.611880704219 9383.106056642382 12494.218679901773 12756.560579098747 4168.238785670604 9476.376905834359 11925.61610485757 1.1260297918961018 1.9220942951480122 0.8082067201952481 0.4618303853048603 0.7868026250501584 1.0476790943163596 1.0696772784680462 0.3495197857302137 0.794623675834611 1.0 13.541776180661765 -5.318326245552464 10.231881158802388 0.7734760319463356 1.5234819016769972 0.5152141725973116 0.28455900531486855 0.43577672762859254 77.19648906698534 0.07407534643177913 0.15454567605765038 4.804782736525164e-06 5.318326245552464 0.7500058697306615 T(ph)PTAPAVNLAGAR ddPTM_PC-9_Lapatinib_30min_R1 4 TPTAPAVNLAGAR 13 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(1)PTAPAVNLAGAR;T(1)PTAPAVNLAGAR;T(1)PTAPAVNLAGAR;T(0.999)PT(0.001)APAVNLAGAR 151.66 0.00030321 82293000.0 13286.2 14249.2 13327.0 12389.900000000001 14454.899999999998 19839.3 31101.6 25903.6 21058.5 16474.5 True False 13096.736351609332 14216.206852868236 12231.305503707687 13301.094577494787 13604.69120142683 18990.81938666711 32711.888666702453 27107.175821741017 18686.669974164124 19322.09537410861 0.6778113914683814 0.7357487155310181 0.6330216918449486 0.688387792315636 0.7041001991769983 0.9828550692340849 1.6929783252460298 1.4029107763366249 0.9671140532306891 1.0 14.237963934484851 -6.973612429223127 4.234885631835323 1.306293445536973 0.6925844173899633 0.6589023845118274 0.19461340969478255 0.12078280152392373 4.998479216189336 0.07318504720381994 0.06176545445506271 1.0626434528088637e-07 6.973612429223127 -0.6137090281470097 T(ph)PTDPGLDSALEPSGDPHGK ddPTM_PC-9_AZD4547_30min_R2 2 TPTDPGLDSALEPSGDPHGK 20 0 Q5T5Y3-2;Q5T5Y3;Q5T5Y3-3 Q5T5Y3-2 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1 1 T(0.972)PT(0.028)DPGLDSALEPSGDPHGK;T(0.838)PT(0.162)DPGLDSALEPSGDPHGK 153.83 3.9614000000000004e-05 4286000.0 25835.8 35456.0 51174.0 49418.0 51582.0 59149.0 59023.0 100055.0 72428.0 61746.0 True False 34051.04698197637 46916.4586201301 50495.39932350237 38025.44360048901 44420.729670131186 55450.40367954998 64275.93265729827 84593.7987851693 76256.39621530737 59584.29133401969 0.5714769147977581 0.7873964357002115 0.8474616076313388 0.6381790023703505 0.7455107491522542 0.9306211828333105 1.078739567396682 1.4197332365832875 1.2798070516241706 1.0 15.862644411551777 -7.180824535928338 1.852569412192815 1.257509535372156 0.7240416091535927 0.7642557597228253 0.1251240087183387 0.15880427509322365 1.06898782729576 0.061884286304205886 0.04130559558888019 6.594402691181841e-08 7.180824535928338 -0.5334679262185632 T(ph)PTPEPAEVETR ddPTM_PC-9_AZD4547_30min_R2 1 TPTPEPAEVETR 12 0 F8W6G1;Q9UHY1 F8W6G1 NRBP1 Nuclear receptor-binding protein 1 T(0.612)PT(0.388)PEPAEVETR 96.756 0.010231 73374000.0 14697.0 12714.0 20765.0 17197.0 20782.0 21960.0 12100.0 21456.0 19653.0 17548.0 True False 19370.34028340933 16823.55186417909 20489.642532390037 13232.497341001457 17896.77802343194 20586.83772849781 13176.876559194026 18140.468209830557 20691.817457605295 16933.6498611955 1.1438963508863884 0.993498271316646 1.2099956418340332 0.7814320863764013 1.0568765842054824 1.2157354083288219 0.7781474559356308 1.0712674679426646 1.2219348827462098 1.0 14.047605343280996 -10.907458355457292 14.608103699664962 1.000002774943425 1.044861922517457 0.008022307757890035 0.15544814553592398 1.9968603672190626e-10 0.0 0.146167610119259 0.03545085268034152 1.2374898472754476e-11 10.907458355457292 0.044859147574031866 T(ph)PTPEPAEVETR ddPTM_PC-9_Lapatinib_30min_R1 1 TPTPEPAEVETR 12 0 F8W6G1;Q9UHY1 F8W6G1 NRBP1 Nuclear receptor-binding protein 1 T(0.754)PT(0.246)PEPAEVETR 129.34 0.00043559999999999996 82445000.0 17705.0 26220.0 34468.0 22647.0 29304.0 27958.0 21708.0 29404.0 28061.0 26211.0 True False 17452.52345330064 26159.289200952 31634.174090327648 24312.535928177316 27580.396333880675 26762.301513281192 22831.93402194023 30770.217184579487 24900.4746845701 30741.53642603785 0.5677179959853433 0.8509428038474772 1.0290368591835815 0.790869252311826 0.8971703935565266 0.8705583592957223 0.7427063405523789 1.0009329643822664 0.8099944758609914 1.0 14.907901650590924 -4.7712985295592905 4.751964577177945 0.8864074363261089 0.547183078407809 0.5312092575727951 0.09081186433707318 0.13390073861026616 7.258239014641889 0.021451215885488137 0.151145894169722 1.6931735302724e-05 4.7712985295592905 -0.33922435791829986 T(ph)PTQTNGSNVPFKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPTQTNGSNVPFKPR 15 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347 A0A494C1K3 GTF2I General transcription factor II-I 1 T(0.836)PT(0.15)QT(0.014)NGSNVPFKPR;T(0.744)PT(0.254)QT(0.001)NGS(0.001)NVPFKPR 82.12100000000001 0.0058541 8620100.0 36827.0 49766.0 43579.0 41959.0 44422.0 34529.0 44508.0 30862.3 33403.0 28243.0 True False 43061.08373359485 54706.43958796391 44618.08863427784 39608.173262913406 35717.82798599521 32718.238455169467 40291.880029984764 30052.197326309823 33891.45568273251 33363.23232853501 1.2906748156042853 1.639722406068384 1.337343102578126 1.1871803329150816 1.070574566465083 0.9806675244468478 1.2076731544840098 0.900757967045258 1.015832499351261 1.0 15.02597144766192 -5.848651492711434 1.837017043873589 1.0289588874492295 1.4708583657358738 0.727081965128627 0.10899932020449325 0.1676492564256816 1.1545550576242345 0.033388434769917055 0.06254676419210525 1.4169303646928634e-06 5.848651492711434 0.44189947828664433 T(ph)PTQTNGSNVPFKPR ddPTM_PC-9_Lapatinib_30min_R1 1 TPTQTNGSNVPFKPR 15 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347 A0A494C1K3 GTF2I General transcription factor II-I 1 T(0.913)PT(0.086)QT(0.001)NGSNVPFKPR 70.117 0.017566 4589500.0 14242.0 18180.0 17533.0 12880.0 16789.0 15038.0 16967.0 11691.0 15380.0 14725.0 True False 14038.906468337065 18137.90532697587 16091.504419337203 13827.23816642045 15801.504028443986 14394.85979529017 17845.468239831396 12234.206540093812 13647.742441420052 17270.196630170823 0.8128978939250331 1.050243127822249 0.9317499252571069 0.8006416176098674 0.9149579687378284 0.8335087378300328 1.0333100787431442 0.7083999564151343 0.7902482371033119 1.0 14.075996888343179 -5.581409329964127 11.447446219906707 0.8640112438095369 0.9464027805680109 0.06392910748556269 0.10628223618278543 1.3682219352590448 262.87373094441494 0.0281796776503142 0.04883099138610449 2.6217463378336516e-06 5.581409329964127 0.082391536758474 T(ph)PTRHLLNGS(ph)LVDGEPPMKRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPTRHLLNGSLVDGEPPMKRR 21 3 Q9P2D1 Q9P2D1 CHD7 Chromodomain-helicase-DNA-binding protein 7 2 T(0.793)PT(0.207)RHLLNGS(1)LVDGEPPMKRR 90.37 0.00074785 0.0 31141.0 31940.0 25756.0 35784.0 34784.0 26690.0 33202.0 29794.0 32340.0 28883.0 True False 36412.55623721391 35110.79211589371 26370.120720173953 33779.13849329331 27968.324899033272 25290.329414940294 30056.866198336334 29011.939069352415 32812.91131873092 34119.259262297826 1.0672141489733395 1.0290607966009255 0.7728808095582907 0.9900314140354051 0.8197225116765238 0.7412332495414518 0.8809354847732441 0.8503097574984854 0.9617123005653749 1.0 15.058298705273359 -5.130230290887312 6.127153945941644 0.8693469721617427 1.0573804644421183 0.40385607078972774 0.08312058904293965 0.2010189990455568 8.978686413492799 0.02070035058871817 0.056866037789174 7.409172550996542e-06 5.130230290887312 0.18803349228037558 T(ph)PTSSPASS(ph)PLVAK ddPTM_PC-9_Lapatinib_30min_R1 1 TPTSSPASSPLVAK 14 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 2 T(0.979)PT(0.018)SS(0.003)PAS(0.032)S(0.968)PLVAK 132.08 0.0003829 4067900.0 25683.0 20896.0 23348.0 21178.0 27241.0 28571.0 34183.0 31670.0 31656.0 20658.0 True False 25316.75571031463 20847.616595846426 21428.417565886328 22735.50076773697 25638.737937866612 27349.084932253976 35952.82848129646 33141.50381701917 28090.567927541844 24228.707774945266 1.044907386125417 0.8604510314580127 0.88442263470796 0.9383703406273936 1.058196672146892 1.1287884267825241 1.483893768303856 1.3678609740504015 1.1593919159233947 1.0 14.564429841029066 -6.73463053193563 2.118980733020371 1.2820144514283505 0.9278853155298178 0.5283886990229858 0.13168594356686364 0.21847064532273683 2.017197202999379 0.051068637214798776 0.047849950588428725 1.8423386707976883e-07 6.73463053193563 -0.3541291358985327 T(ph)PTSSPASSPLVAK ddPTM_PC-9_Lapatinib_30min_R1 1 TPTSSPASSPLVAK 14 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 T(0.913)PT(0.036)S(0.025)S(0.025)PAS(0.001)S(0.001)PLVAK 118.76 0.0002712 45477000.0 224000.0 193280.0 195310.0 204670.0 263630.0 285250.0 246670.0 242180.0 339470.0 283050.0 True False 220805.7189234306 192832.47203508814 179252.36571840264 219722.11455910467 248123.80171652194 273050.5224502275 259441.36563442028 253432.56692155657 301235.31382242276 331974.81535958237 0.6651279214788095 0.5808647617627843 0.5399577239744628 0.6618638053043575 0.7474175456585879 0.8225037256349391 0.7815091797051031 0.763409015370784 0.9074041158698627 1.0 18.34071427283432 -7.21032742622296 0.31461515864982187 1.0112129288262457 0.5224199884518301 0.8369618304066457 0.05437075806290887 0.7495556165383156 0.1930895420946273 0.08551727988410239 0.1321540088286662 6.16130309595775e-08 7.21032742622296 -0.48879294037441556 T(ph)PTSTPVHVK ddPTM_PC-9_AZD4547_30min_R2 2 TPTSTPVHVK 10 0 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 T(0.83)PT(0.054)S(0.1)T(0.016)PVHVK;T(0.781)PT(0.09)S(0.115)T(0.014)PVHVK 87.001 0.022871000000000002 9284400.0 44809.0 56410.0 84654.0 87245.0 69696.0 92403.0 80616.0 103788.0 75785.0 80571.0 True False 59057.32991490021 74643.42934232665 83531.43264805901 67132.01317181313 60019.91344053096 86625.02580265864 87790.66782611464 87749.94941097559 79790.84038185599 77750.23381390382 0.7595775217378083 0.9600412202101752 1.074356031494292 0.8634316564564226 0.7719579800131455 1.1141448913195136 1.1291370266003666 1.1286133186558154 1.026245664711908 1.0 16.24655939333484 -6.78254347315585 24.9998018338206 1.0907608801453161 0.8992178820677956 0.514320952144872 0.0933810276745997 213.14145533219073 252484.54376778548 0.03449978984003668 0.030455771070708123 1.6498958374236008e-07 6.78254347315585 -0.1915429980775205 T(ph)PTSTPVHVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPTSTPVHVK 10 0 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 T(0.89)PT(0.095)S(0.014)T(0.002)PVHVK 97.911 0.010407 4651000.0 17211.0 24753.0 28346.0 26345.0 28334.0 26730.0 26538.0 22776.0 19395.0 16923.0 True False 20124.482367255034 27210.314253122007 29021.876142803634 24868.975061642406 22782.156097320873 25328.231744524313 24024.128521518283 22178.154133166776 19678.615183264887 19991.00593760571 1.0066768240710806 1.3611278160813223 1.4517466621431825 1.2440081874449647 1.1396202956682955 1.266981352693142 1.2017468553858883 1.10940661027201 0.9843734349679134 1.0 14.287063449164817 -7.9087361155947375 1.4877752815584775 0.9824236033635761 1.2575920073070042 0.43981285946356374 0.11251672781096676 0.396449543118817 1.591052405004855 0.10065841401369194 0.03541742617793587 1.233854315498275e-08 7.9087361155947375 0.275168403943428 T(ph)PTSTPVHVK ddPTM_PC-9_Lapatinib_30min_R1 2 TPTSTPVHVK 10 0 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 T(0.955)PT(0.014)S(0.029)T(0.002)PVHVK;T(0.97)PT(0.025)S(0.004)T(0.001)PVHVK 107.85 0.004431399999999999 13083400.0 74685.0 82392.0 90219.0 76668.0 87074.0 88160.0 77074.0 72287.0 82493.0 68131.0 True False 73619.97820444829 82201.22638614944 82801.54207541126 82306.42047695046 81952.4785140706 84389.6023109975 81064.51459402168 75645.71791666764 73201.7696501992 79907.35257114904 0.9213166978457644 1.0287066676743915 1.0362193141323917 1.0300231183815696 1.0255937141841933 1.056093082746766 1.0144812959713851 0.9466678031826061 0.9160830298441033 1.0 16.286040636518734 -7.746018089220653 6.579348851839871 0.9482336567050993 1.0199755556506684 0.339093374741982 0.03904276726299863 0.14965976918011276 26.282556354408236 0.019403510276602753 0.010473433961300658 1.794658874198474e-08 7.746018089220653 0.07174189894556915 T(ph)PVGSPWPR ddPTM_PC-9_Lapatinib_30min_R1 1 TPVGSPWPR 9 0 A0A1C7CYW6;A0A1B0GWB1;A0A1B0GTQ2;P0DI83 A0A1C7CYW6 RAB34 Ras-related protein Rab-34, isoform NARR 1 T(0.999)PVGS(0.001)PWPR 84.81700000000001 0.031577 2883900.0 6419.2 8091.6 9378.9 4631.7 6954.5 6167.3 7016.3 5280.4 8063.0 6482.0 True False 6327.6610308628915 8072.86439734642 8607.803045600964 4972.330668898258 6545.449983073064 5903.538955678484 7379.569682980437 5525.746661047933 7154.860032845899 7602.405063277918 0.8323235842072592 1.0618829607410651 1.1322473577709564 0.6540470584652518 0.8609709596624507 0.776535702391667 0.9706888309103855 0.7268419158220182 0.941131125386385 1.0 12.892240180055834 -5.747612053504303 24.999998766847828 0.8385701465786518 1.014124420017737 0.2603161507009272 0.12417782295918602 289.9700581869576 524265.65234781406 0.03223861922584891 0.05547017222525144 1.7880841211226595e-06 5.747612053504303 0.17555427343908525 T(ph)PVQDHR ddPTM_PC-9_AZD4547_30min_R2 2 TPVQDHR 7 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(1)PVQDHR;T(1)PVQDHR 108.43 0.020469 7108900.0 22952.0 20094.7 26493.0 24219.0 22902.0 24277.0 27771.0 22687.0 26867.0 32417.0 True False 30250.258568742647 26589.91880172406 26141.685509781317 18635.683729819968 19722.45261729567 22758.955352219567 30242.565200444405 19181.24544539643 28287.134769932425 31282.090696966865 0.9670152440187041 0.8500045300457567 0.8356757789311069 0.595730122719288 0.6304710515786585 0.727539459324766 0.9667693087846186 0.6131701883741504 0.9042597262425036 1.0 14.933049316023062 -9.714927958522726 16.238926839555866 0.9999999999641142 0.7791549017916997 0.18090972755807233 0.13428432010159072 0.0 0.0 0.13306822333288676 0.032273784718516045 1.927844680689625e-10 9.714927958522726 -0.2208450981724145 T(ph)PVQDHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPVQDHR 7 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(1)PVQDHR;T(1)PVQDHR 93.195 0.029522000000000003 6110700.0 14574.9 26594.0 23117.0 16155.900000000001 30334.0 23609.0 15993.7 15539.9 18978.7 18162.5 True False 17042.142702603305 29234.0765663769 23668.196951710695 15250.737301134506 24390.27045444099 22370.90247873082 14478.66095163941 15131.994090885055 19256.22758332711 21455.21747572912 0.794312279606672 1.3625625841102516 1.1031441176713763 0.7108171855347849 1.1367990318453822 1.0426788963587785 0.674831703198449 0.7052827177353428 0.8975079187666317 1.0 14.389040904246365 -7.242951018686376 23.793103163996932 0.7948458187863667 1.0347393613824694 0.21467609862393866 0.18984465939380304 602.0783715302808 774829.3726746438 0.07283506021707944 0.05629148650182178 5.71543093748955e-08 7.242951018686376 0.23989354259610263 T(ph)PVQDHR ddPTM_PC-9_Lapatinib_30min_R1 2 TPVQDHR 7 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(1)PVQDHR;T(1)PVQDHR 107.55 0.020741 6673300.0 10178.0 23578.2 20517.1 24899.4 29290.4 21936.5 22185.0 24173.0 34245.0 28248.9 True False 10032.85985358339 23523.60612654028 18830.26323629632 26730.584937963464 27567.596259142058 20998.327031479086 23333.63074796131 25296.16582787511 30387.96748416317 33131.68472570679 0.30281767850455604 0.7100033192181251 0.5683460829773611 0.806798240393229 0.8320614085088293 0.6337838599311111 0.7042693705779713 0.7635037589334501 0.9171875120671187 1.0 15.015923944985447 -4.301512919428072 0.19305592111928263 0.9815528339739314 4.314874971561945e-30 0.6083846182062094 0.11605654015501905 15.25635674730669 0.4605988447229491 0.2786989374038989 3.7271132766308956 4.994443224763513e-05 4.301512919428072 -0.9815528339739314 T(ph)PVSPQVTDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPVSPQVTDSK 11 0 C9JM94;B5MCC4;E7EX78;O14901-2;O14901 C9JM94 KLF11 Krueppel-like factor 11 1 T(0.51)PVS(0.489)PQVTDSK 104.59 0.004159 0.0 13545.0 9716.1 15691.0 17287.0 22844.0 20210.0 20573.0 17699.0 15036.0 14014.0 True False 15837.900974055516 10680.650196532088 16065.13294844887 16318.465435210182 18367.882187026113 19150.152022328333 18624.176504378443 17234.42000364062 15255.873054682686 16554.627265237046 0.9567053803327497 0.6451761205738721 0.9704315712492022 0.9857343915847155 1.1095316066461194 1.1567854543328566 1.1250133395323996 1.0410636088334688 0.9215473601582317 1.0 14.014946907732396 -5.56873792832185 2.7816565910276023 1.0622631277699142 0.8002729197591941 0.484659402787343 0.098462622613838 0.20080866511057227 3.127112340377402 0.027647543686656038 0.05810097549608112 2.699367853918954e-06 5.56873792832185 -0.26199020801072004 T(ph)PVYT(ph)TS(ph)MR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPVYTTSMR 9 0 A0A0J9YY17;A0A1C7CYW8;A0A669KB38;Q8IVF4 A0A0J9YY17 DNAH10 Dynein heavy chain 10, axonemal 3 T(0.998)PVY(0.007)T(0.615)T(0.612)S(0.768)MR 72.789 0.026716000000000004 1526500.0 0.0 1008.7 1101.8 854.34 1954.5 1765.9 785.08 744.2 1194.7 869.24 True False 0.0 1108.837069733938 1128.0710905997694 806.4740996076508 1571.529755495646 1673.2930953107186 710.7115389130138 724.6655385450782 1212.170227349655 1026.8263310999455 0.0 1.079868168696202 1.0985996915285272 0.7854045763938957 1.5304727858042064 1.6295775094881646 0.6921438585935883 0.7057333032829515 1.1805016979367557 1.0 10.00397648146157 -4.761434206972132 24.991941501010526 1.079651214179703 5.6586033341470884e-05 0.5377443642239491 0.29984844338285854 0.11416476077254237 494812.8741321313 0.08002414903234159 0.44570029975113534 1.7320714093795797e-05 4.761434206972132 -1.0795946281463615 T(ph)PYPHPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPYPHPR 7 0 A8MQ11;O95744;A4D2B8-3;A4D2B8-2;A4D2B8 A8MQ11 PMS2P5;PMS2P2;PMS2P1 Postmeiotic segregation increased 2-like protein 5;Putative postmeiotic segregation increased 2-like protein 2;Putative postmeiotic segregation increased 2-like protein 1 1 T(0.999)PY(0.001)PHPR 75.21300000000001 0.044095999999999996 0.0 6741.9 8185.2 8680.0 7655.0 11315.0 9630.0 9177.6 10105.0 8970.7 8338.8 True False 7883.170511405306 8997.772561897726 8886.964119083315 7226.1151678448505 9097.906975407126 9124.985847353882 8308.23128792999 9839.754457132512 9101.879516602952 9850.55843009552 0.8002765089256837 0.9134276625787676 0.9021787122171447 0.7335741642593129 0.9235930165757014 0.926341984782826 0.8434274408795549 0.9989032121336392 0.9239962973870398 1.0 13.265989798215161 -7.714372832387945 0.6399601762246994 0.9950739705512277 0.8502110583981549 0.3790213990360094 0.06230783321534127 0.8137174582695637 0.67303707711225 0.058779816506504844 0.03200830751374259 1.9303104758551976e-08 7.714372832387945 -0.1448629121530728 T(ph)QDPSSPGTTPPQAR ddPTM_PC-9_Lapatinib_30min_R1 1 TQDPSSPGTTPPQAR 15 0 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 T(0.56)QDPS(0.261)S(0.149)PGT(0.023)T(0.006)PPQAR 92.11200000000001 0.009031200000000001 4113800.0 15501.0 17083.0 19594.0 15470.0 16723.0 16132.0 11488.0 13091.0 17852.0 14475.0 True False 15279.952897464753 17043.445363076386 17983.056955027274 16607.715406407162 15739.386018683 15442.071965528721 12082.792428784296 13699.25565104509 15841.319770106033 16976.984463274883 0.9000392814471145 1.003914764718391 1.0592609655695189 0.9782488428574265 0.9271013973495063 0.9095886256439399 0.7117160562243637 0.8069310354073616 0.9331056292343582 1.0 14.051292602501954 -6.667204058270383 2.184526109016539 0.8462517107041948 0.9899847335247445 0.2856240874993793 0.08152403063278382 0.3335451671777516 3.258817211451897 0.03128544036964127 0.030655773729194022 2.1517704629989853e-07 6.667204058270383 0.14373302282054967 T(ph)QLSPSIK ddPTM_PC-9_Lapatinib_30min_R1 1 TQLSPSIK 8 0 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 T(0.996)QLS(0.004)PSIK 93.667 0.017245 17968000.0 38940.0 60114.0 66776.0 59326.0 72139.0 58529.0 64457.0 68080.0 68295.0 64441.0 True False 38384.70845927857 59974.80972639313 61285.93504281421 63689.03194573447 67895.92585073086 56025.85110776288 67794.26806947678 71243.24533825909 60602.89792176737 75579.54098776486 0.5078716800554854 0.7935323361662397 0.8108799582778022 0.8426755589326047 0.8983373670094416 0.7412832940707139 0.8969923233650176 0.9426260652971186 0.8018426300257371 1.0 16.20570813634941 -4.402772516527342 1.3792762639602834 0.8661584681596219 2.0770760878542385e-15 0.7055361405562519 0.06962369116694021 1.7224814774060504 1.477810096531753 0.019288459680751022 2.677870250338327 3.955737673718396e-05 4.402772516527342 -0.8661584681596198 T(ph)QQSPISNGSPELGIK ddPTM_PC-9_Lapatinib_30min_R1 1 TQQSPISNGSPELGIK 16 0 Q15723-2;Q15723-3;Q15723-1;Q15723 Q15723-2 ELF2 ETS-related transcription factor Elf-2 1 T(0.501)QQS(0.285)PIS(0.143)NGS(0.071)PELGIK 115.58 0.00042498 7799700.0 42683.0 32885.0 37288.0 36588.0 35997.0 39035.0 32249.0 31170.0 39586.0 30580.0 True False 42074.33259289645 32808.85680294837 34222.32457584246 39278.80357399 33879.72723282496 37365.56404502934 33918.695424431135 32618.271991679423 35127.40782093981 35865.71225471128 1.1731074039208467 0.9147694201622508 0.9541794216381986 1.0951630709307991 0.944627196923283 1.0418185418894348 0.9457136995787839 0.9094555758444396 0.9794147561178158 1.0 15.13031766098616 -7.276101002522902 24.041226333935782 0.9511006294745294 1.0127151942751416 0.13334272614947484 0.07482130322448052 1021.533859150039 1675039.6254372497 0.030187017197540317 0.020469858252741648 5.2954027602750774e-08 7.276101002522902 0.061614564800612115 T(ph)QSAPLPQNAQALQHLVIQQQHQQFLEK ddPTM_PC-9_AZD4547_30min_R2 3 TQSAPLPQNAQALQHLVIQQQHQQFLEK 28 0 P56524-2;P56524 P56524-2 HDAC4 Histone deacetylase 4 1 T(0.766)QS(0.234)APLPQNAQALQHLVIQQQHQQFLEK;T(0.692)QS(0.308)APLPQNAQALQHLVIQQQHQQFLEK;T(0.5)QS(0.5)APLPQNAQALQHLVIQQQHQQFLEK 97.479 2.6183999999999998e-06 111665000.0 62448.1 69180.3 91978.0 133241.8 98805.9 104447.8 88219.9 97032.6 84012.3 97099.7 True False 82305.29679882787 91541.47908049937 90758.31162264237 102524.9615752892 85088.40629898038 97916.66255458063 96071.30019540837 82038.44125732676 88453.01866349019 93700.26905784855 0.8783891191178366 0.9769606853955095 0.9686024654487398 1.0941800125674397 0.9080913764126826 1.0449987341458857 1.0253044218698668 0.8755411492647687 0.9439996229774024 1.0 16.515765570100577 -10.47621202605865 12.462307024114432 0.9999999997811522 0.9718202045406991 0.016939274414243033 0.06786658397792278 0.0 0.0 0.06587747606273069 0.01597763495173311 3.340319231407127e-11 10.47621202605865 -0.02817979524045311 T(ph)QSAPLPQNAQALQHLVIQQQHQQFLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQSAPLPQNAQALQHLVIQQQHQQFLEK 28 0 P56524-2;P56524 P56524-2 HDAC4 Histone deacetylase 4 1 T(0.941)QS(0.059)APLPQNAQALQHLVIQQQHQQFLEK 105.79 3.1223000000000003e-09 38160000.0 70128.0 63986.0 66374.0 88797.0 83896.0 76153.0 78032.0 77905.0 67426.0 73763.0 True False 81999.2853088642 70338.10721125783 67956.60788479673 83821.99197375838 67457.18105247508 72159.40262030537 70640.24405724298 75860.07629717047 68411.97769254034 87135.64799241326 0.9410532565960115 0.807225387448568 0.7798944456201621 0.9619712930930016 0.7741628438724465 0.8281272278664658 0.8106928184363017 0.8705974884558783 0.7851204331262545 1.0 16.41097543890588 -10.734522673313428 5.301461803156482 1.000010683569 0.838506090836208 0.3711315043891098 0.06250969791268625 7.489707662725377e-06 1.113800666032581e-06 0.05742971375587035 0.013927830436869983 1.842796279163497e-11 10.734522673313428 -0.16150459273279194 T(ph)QSAPLPQNAQALQHLVIQQQHQQFLEK ddPTM_PC-9_Lapatinib_30min_R1 3 TQSAPLPQNAQALQHLVIQQQHQQFLEK 28 0 P56524-2;P56524 P56524-2 HDAC4 Histone deacetylase 4 1 T(0.967)QS(0.033)APLPQNAQALQHLVIQQQHQQFLEK;T(0.884)QS(0.116)APLPQNAQALQHLVIQQQHQQFLEK;T(0.946)QS(0.054)APLPQNAQALQHLVIQQQHQQFLEK 107.72 2.3719e-09 48838000.0 154495.0 130959.0 130182.0 107560.0 129008.0 114349.0 117533.0 111105.0 132663.0 100077.0 True False 152291.87296908683 130655.77248159677 119478.9384770522 115470.32120964165 121420.00307948655 109458.55983053843 123618.28364661429 116267.34390874374 117721.09593667818 117375.17610577957 1.2974793991519982 1.1131465512251808 1.0179234011915492 0.9837712286418958 1.0344606679870856 0.9325528911828289 1.0531893348147856 0.9905616141863128 1.002947129387792 1.0 16.840767796888763 -4.740371864224092 1.619514118586611 0.999331670748089 1.429149365284093 0.901862105207132 0.03011203450855919 0.29860982487376964 0.7048122108545025 0.00796695585982245 0.21033994279391482 1.8181434084126606e-05 4.740371864224092 0.42981769453600394 T(ph)QSAPLPQSTLAQLVIQQQHQQFLEK ddPTM_PC-9_AZD4547_30min_R2 1 TQSAPLPQSTLAQLVIQQQHQQFLEK 26 0 Q9UKV0-10;Q9UKV0-3;Q9UKV0-4;Q9UKV0-2;Q9UKV0;Q9UKV0-5;Q9UKV0-7;B7Z3P7;B5MCF1;Q9UKV0-11;Q9UKV0-9;Q9UKV0-8;Q9UKV0-6 Q9UKV0-10 HDAC9 Histone deacetylase 9 1 T(0.482)QS(0.416)APLPQS(0.051)T(0.051)LAQLVIQQQHQQFLEK 100.55 5.1271e-09 8140000.0 16535.0 14705.0 23669.0 34844.0 32353.0 24536.0 23730.0 27227.0 27103.0 25804.0 True False 21792.786050634364 19458.10367805203 23355.133594950148 26811.254134433602 27861.34440343056 23001.760041276062 25841.924028898702 23019.692764217776 28535.60924812886 24900.609814126336 0.8751908573046723 0.7814308092572607 0.9379342019849078 1.0767308244484575 1.1189020916116108 0.9237428405559354 1.0378028579138794 0.9244630125949165 1.1459803378767197 1.0 14.603893453772244 -5.502265406930988 4.372252200365343 1.0281400480321365 0.8313844639779424 0.5631460121636536 0.07189644124856663 0.14213796306633916 6.513343418435969 0.019094683326630717 0.0387374043568285 3.1458252433964608e-06 5.502265406930988 -0.19675558405419413 T(ph)QSAPLPQSTLAQLVIQQQHQQFLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQSAPLPQSTLAQLVIQQQHQQFLEK 26 0 Q9UKV0-10;Q9UKV0-3;Q9UKV0-4;Q9UKV0-2;Q9UKV0;Q9UKV0-5;Q9UKV0-7;B7Z3P7;B5MCF1;Q9UKV0-11;Q9UKV0-9;Q9UKV0-8;Q9UKV0-6 Q9UKV0-10 HDAC9 Histone deacetylase 9 1 T(0.381)QS(0.322)APLPQS(0.251)T(0.046)LAQLVIQQQHQQFLEK 108.8 1.1820999999999999e-09 5971800.0 24862.0 26636.0 26493.0 38851.0 31507.0 27294.0 31170.0 33138.0 24292.0 21677.0 True False 29070.645553116858 29280.24604880857 27124.693595262008 36674.304426641465 25333.429524891937 25862.65459165907 28217.351948742336 32268.16261261327 24647.224544051085 25606.868504962415 1.1352674985417757 1.1434528217745283 1.059274139280461 1.4322057544652236 0.9893216548514128 1.0099889639628166 1.1019446576715943 1.2601370060677255 0.9625239626342691 1.0 14.644243214343746 T(ph)QSAPLPQSTLAQLVIQQQHQQFLEK ddPTM_PC-9_Lapatinib_30min_R1 1 TQSAPLPQSTLAQLVIQQQHQQFLEK 26 0 Q9UKV0-10;Q9UKV0-3;Q9UKV0-4;Q9UKV0-2;Q9UKV0;Q9UKV0-5;Q9UKV0-7;B7Z3P7;B5MCF1;Q9UKV0-11;Q9UKV0-9;Q9UKV0-8;Q9UKV0-6 Q9UKV0-10 HDAC9 Histone deacetylase 9 1 T(0.688)QS(0.293)APLPQS(0.016)T(0.004)LAQLVIQQQHQQFLEK 100.55 5.1271e-09 4883900.0 19966.0 19649.0 15033.0 13264.0 17727.0 18614.0 15076.0 12171.0 16235.0 16289.0 True False 19681.28117868403 19603.503947730966 13797.044769058137 14239.478807406897 16684.332712622945 17817.9226113533 15856.561512565462 12736.509092419976 14406.44333787091 19104.53194627182 1.030189131774294 1.0261179914201728 0.7221870081852793 0.7453455990156136 0.8733180566550771 0.932654234160937 0.8299895311311101 0.6666747517415865 0.7540851238013332 1.0 14.221627292200946 -5.246320738134309 24.22105100688396 0.8078837564295577 1.028153645170133 0.4403241539602354 0.09557413846270049 492.1288075151398 788417.1618753193 0.025230143845423523 0.06612899383578433 5.671256132182225e-06 5.246320738134309 0.2202698887405753 T(ph)QSESGDVSR ddPTM_PC-9_Lapatinib_30min_R1 1 TQSESGDVSR 10 0 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 T(0.874)QS(0.124)ES(0.001)GDVSR 91.31299999999999 0.013935 0.0 5558.4 6003.1 9384.4 7655.6 11468.0 11758.0 15439.0 15244.0 15442.0 15581.0 True False 5479.136196714278 5989.200190779362 8612.850856831574 8218.618362332947 10793.47478695549 11255.137749236714 16238.35587639283 15952.291890958011 13702.759348531106 18274.155089622527 0.2998297962254766 0.3277415651452193 0.47131321883782273 0.44973999191897585 0.590641522632412 0.6159046858274858 0.8885968077185806 0.8729427879276865 0.7498436606961155 1.0 14.157517083883642 -6.5462567182452425 0.46617549446438966 0.9627316788852696 0.2292237555042516 0.9165889032097042 0.0669166497360279 0.33855474140564684 0.14962695902177542 0.06270080798052308 0.10964462614568213 2.8427801989552046e-07 6.5462567182452425 -0.733507923381018 down T(ph)QSLPVTEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQSLPVTEK 9 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 T(0.997)QS(0.001)LPVT(0.003)EK 123.01 0.0037213000000000003 90008000.0 123730.0 113250.0 83882.0 83750.0 73303.0 62717.0 68196.0 83263.0 57205.0 47832.0 True False 144675.0452211069 124492.71155682413 85882.06500425664 79057.7590211633 58939.80335998846 59428.010113031494 61735.98118371623 81077.43447444067 58041.51490377253 56503.56296209631 2.560458803600717 2.203271882878187 1.5199406993478979 1.3991641389799931 1.0431165800911781 1.051756862711418 1.092603332379764 1.4349083531038387 1.0272186719040692 1.0 15.786054222399011 -5.189475205346979 1.2116274578842687 1.1295185729696928 2.7812298130033457 0.9373649855698734 0.12855595605167 0.18520068464896422 0.3708986638652021 0.04190273601493005 0.32150029382374323 6.464348990769927e-06 5.189475205346979 1.6517112400336529 up T(ph)QSLSALPK ddPTM_PC-9_Lapatinib_30min_R1 1 TQSLSALPK 9 0 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 T(0.745)QS(0.164)LS(0.091)ALPK 85.288 0.030687 56115000.0 116350.0 114450.0 136520.0 103210.0 159950.0 162600.0 154070.0 161460.0 165440.0 129920.0 True False 114690.82766402325 114184.99805678723 125295.8525824394 110800.40769846682 150542.05547379932 155645.97703911312 162046.99072970042 168962.02103870874 146806.40503956663 152376.49889248208 0.7526805544006487 0.7493609505843611 0.8222780644858433 0.727148927188886 0.9879611132161715 1.021456577427586 1.063464457495128 1.1088456702101386 0.9634451907387257 1.0 17.217280886810535 -6.355478213865776 4.054655822152806 1.037122702559358 0.7659264334054289 0.8973502143648069 0.043376818501533236 0.0678869867582981 2.008276436307168 0.013858290843386236 0.015940150139875178 4.4108448931751925e-07 6.355478213865776 -0.271196269153929 T(ph)QSPEFEAQSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQSPEFEAQSSK 12 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 T(0.992)QS(0.008)PEFEAQSSK 138.21 0.00016808 4851400.0 25339.0 23593.0 25575.0 27731.0 25028.0 21493.0 27018.0 18950.0 17744.0 17220.0 True False 29628.392231937432 25935.157119294945 26184.804993727605 26177.321975115046 20123.943065001284 20365.869243735913 24458.659446619222 18452.58257918467 18003.472431650014 20341.849686555015 1.4565239979882643 1.2749655276647156 1.287238151751485 1.2868702885174201 0.9892877675869487 1.001180795136677 1.2023812889928698 0.9071241240849862 0.8850459869217028 1.0 14.312163249123005 -5.772012432284688 0.5261012817242415 0.9470088721621107 1.5072681132814625 0.7459480877185862 0.09364294785970391 0.9224346515163487 0.3968223025065397 0.0703885485646723 0.28547262422906217 1.6903925411087706e-06 5.772012432284688 0.5602592411193518 T(ph)QSPEFEAQSSK ddPTM_PC-9_Lapatinib_30min_R1 1 TQSPEFEAQSSK 12 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 T(0.982)QS(0.018)PEFEAQSSK 178.14 0.0021376 39924000.0 29969.0 51052.0 47999.0 49391.0 49590.0 49647.0 55465.0 48818.0 41809.0 38559.0 True False 29541.636564358476 50933.79223062552 44052.70750149811 53023.37890354597 46673.21369769117 47523.713542809586 58336.7063076707 51086.26249887096 37100.03015171202 45223.871773362116 0.653231034980936 1.1262589918412664 0.9741029631931283 1.172464382732881 1.0320481610153236 1.0508545969034462 1.289953823503284 1.1296304472754568 0.8203638630862379 1.0 15.464796891079686 -4.757299143490123 24.987191895871437 1.0761277031695908 0.6532304134105205 0.5134770791009986 0.12024119279243038 97.90665427941472 590807.9722595761 0.02961077207533184 0.2224169189301677 1.7486418033913805e-05 4.757299143490123 -0.42289728975907037 T(ph)QSSASLAASYAAQQHPQAAASYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQSSASLAASYAAQQHPQAAASYR 24 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 T(0.347)QS(0.347)S(0.149)AS(0.149)LAAS(0.008)YAAQQHPQAAASYR 67.788 0.025869 0.0 3116.6 3199.5 2509.0 6038.5 4790.5 5315.3 1277.1 2038.8 5643.1 2862.9 True False 3644.1788243441397 3517.1252152411403 2568.824075435487 5700.182422081144 3851.8359138919873 5036.556310949127 1156.1238425966906 1985.2836602871619 5725.619661803663 3381.921107296071 1.077546964795329 1.039978492595047 0.7595753992881652 1.685486515277874 1.1389490741171147 1.4892589599690507 0.3418541727961951 0.5870283774521413 1.6930080507943712 1.0 11.723627289933262 -7.22977482982691 24.987922122841404 0.871057815221221 1.1907442950351077 0.11089573405208952 0.40136916293255454 1445.5813843614214 1140774.9956044569 0.15492919374449599 0.1199968987135158 5.8914903433569015e-08 7.22977482982691 0.31968647981388665 T(ph)QSSSCERDSPSTSR ddPTM_PC-9_AZD4547_30min_R2 1 TQSSSCERDSPSTSR 15 1 Q5JS79;A0A2U3TZM1;A0A2R8YE77;A0A2R8YEK3;O14936-6;O14936-2;O14936 Q5JS79 CASK Peripheral plasma membrane protein CASK 1 T(0.765)QS(0.114)S(0.019)S(0.012)CERDS(0.086)PS(0.004)TSR 70.438 0.017095 13931000.0 6577.0 8226.8 11290.0 11094.0 9094.9 7379.0 11215.0 10380.0 7751.9 7492.1 True False 8668.349189901557 10885.95221615766 11140.287223245045 8536.449700591387 7832.230124401465 6917.589963505706 12213.113273666197 8776.009508670822 8161.649608182492 7229.80385941776 1.1989743232950787 1.505705054775074 1.5408837417813723 1.180730468845507 1.0833253953631075 0.9568157169982758 1.6892731132334977 1.2138655044201412 1.128889492285587 1.0 12.819740792850416 -14.522878636844203 0.07061623482096861 0.039813764588668574 1.6247794975798966 0.1596501212956587 0.21352990151247336 627.0909210937832 3.1731948135347348 98.00383875589479 11.929707566601325 3.000000749050377e-15 14.522878636844203 1.5849657329912281 T(ph)QSTFDPFEKPANQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TQSTFDPFEKPANQVK 16 1 O94921;O94921-3;O94921-2;C9JWL6;F8WF96;C9IYJ9 O94921 CDK14 Cyclin-dependent kinase 14 1 T(0.381)QS(0.309)T(0.309)FDPFEKPANQVK;T(0.396)QS(0.341)T(0.263)FDPFEKPANQVK 76.118 0.0084633 16355300.0 128432.0 102921.0 92141.0 99602.0 106897.0 86352.0 84288.0 109106.0 71889.0 80689.0 True False 150173.00095237355 113138.31669880702 94337.9908866882 94021.62285404067 85951.30021653505 81823.54910599193 76303.6304477254 106242.08310736288 72940.2406243738 95317.27696622735 1.575506620962143 1.1869654725752812 0.9897260380205141 0.9864069332084912 0.9017389391745755 0.8584335569613839 0.8005225587252264 1.1146151724939266 0.7652363028605805 1.0 16.540450116606017 -4.269195140960304 0.988938641581034 0.9078589058614188 2.7744619691724615 0.8225290113315735 0.09429206529229776 1.753010254781185 0.6824997679714162 0.029188117162659642 4.439297989004313 5.380279768020273e-05 4.269195140960304 1.8666030633110426 T(ph)QTESSTPPGIPGGSR ddPTM_PC-9_Lapatinib_30min_R1 1 TQTESSTPPGIPGGSR 16 0 E9PER6;Q6A1A2;O15530-4;O15530-5;O15530;H3BQ10;O15530-3 E9PER6 PDPK1;PDPK2P Putative 3-phosphoinositide-dependent protein kinase 2;3-phosphoinositide-dependent protein kinase 1 1 T(0.778)QT(0.125)ES(0.076)S(0.011)T(0.011)PPGIPGGSR 162.76 0.00015535 8785100.0 29738.0 22886.0 26593.0 23943.0 23786.0 22767.0 17844.0 19540.0 29471.0 16970.0 True False 29313.9306667187 22833.008873111663 24406.62619194857 25703.848091506596 22386.95424507528 21793.308482469143 18767.87500863745 20447.899734277074 26151.66563661188 19903.241888896366 1.472821906619764 1.1472004912852793 1.2262638583297607 1.2914402706348194 1.1247893368348465 1.0949627504968027 0.9429556809590746 1.0273652829233093 1.3139399994531238 1.0 14.28071581916802 -6.406714587796461 2.816920386806809 1.070154404996739 1.271787717710711 0.40596159334390847 0.11914884076770345 0.3018601112324994 4.631514110187144 0.04007835542796045 0.045850778805872856 3.9199940895394887e-07 6.406714587796461 0.201633312713972 T(ph)QTPPLGQTPQLGLK ddPTM_PC-9_AZD4547_30min_R2 1 TQTPPLGQTPQLGLK 15 0 H0Y3P2;D3DQV9;P78344-2;P78344;E9PKF8 H0Y3P2 EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 1 T(0.495)QT(0.495)PPLGQT(0.009)PQLGLK 85.845 0.013848 4330500.0 12933.0 12314.0 17979.0 19599.0 21604.0 17212.0 16102.0 18846.0 17077.0 20744.0 True False 17045.424976888666 16294.259686605421 17740.586712730077 15080.753351531508 18604.657512184767 16135.730919075793 17535.046806292736 15933.783737997142 17979.655356613537 20017.758873982184 0.8515151513311128 0.8139902068549576 0.8862424022795163 0.7533687185698154 0.9294076139745056 0.8060708004654804 0.8759745242552441 0.795982399343758 0.8981852299151407 1.0 14.288992843115059 -8.567389593427974 5.468151069427896 0.999981300098251 0.8403032598370431 0.51775841285083 0.047796979788960484 0.20679356618468986 21.970115440868014 0.04157964030968111 0.010793794831331716 2.7077614849815382e-09 8.567389593427974 -0.1596780402612079 T(ph)QTPPLGQTPQLGLK ddPTM_PC-9_Lapatinib_30min_R1 1 TQTPPLGQTPQLGLK 15 0 H0Y3P2;D3DQV9;P78344-2;P78344;E9PKF8 H0Y3P2 EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 1 T(0.589)QT(0.411)PPLGQTPQLGLK 125.61 6.3435e-05 13985000.0 40360.0 53642.0 43070.0 50397.0 42245.0 43220.0 36134.0 38346.0 39613.0 26586.0 True False 39784.45899888247 53517.79524475465 39528.95085500787 54103.36349946363 39760.232156865575 41371.58135074085 38004.84171498011 40127.69514895538 35151.36679661719 31181.354676381765 1.2759054060283372 1.7163396459260174 1.267711145499043 1.7351190819314877 1.275128440361889 1.3268051301849835 1.2188322832480007 1.2869131429799616 1.127320065514745 1.0 14.928395986945095 -7.616835670506078 0.5064629574485887 1.0116302684326937 1.5115951186359886 0.47991725297784904 0.15913343579484437 0.7353959752802239 0.424109683702332 0.15037571780940281 0.10877226842881321 2.416374975836357e-08 7.616835670506078 0.49996485020329495 T(ph)QTPPVEENVTQK ddPTM_PC-9_AZD4547_30min_R2 2 TQTPPVEENVTQK 13 0 Q6P1Q9-2;Q6P1Q9 Q6P1Q9-2 METTL2B Methyltransferase-like protein 2B 1 T(0.621)QT(0.379)PPVEENVTQK;T(0.594)QT(0.406)PPVEENVTQK 174.24 0.00044523 25425000.0 36002.0 33384.0 38549.0 49522.0 45647.0 41319.0 38658.0 40116.0 36539.0 38761.0 True False 47449.88711188016 44174.72514029847 38037.81507253086 38105.46800727299 39309.70197457407 38735.31639816946 42098.48710953079 33916.99397397288 38470.376944153075 37403.98918793019 1.268578249059907 1.1810164129379312 1.0169454087214098 1.0187541177979262 1.0509494529331869 1.0355931877626805 1.1255079477756735 0.9067747775127013 1.028510000654342 1.0 15.190904523318352 -5.098333386739923 2.7495142339911207 1.0237881177942794 1.2641522205680245 0.7237914112539319 0.05112679876233616 0.15139050649542235 2.0898117617051635 0.013737545247748395 0.05819825891514317 7.973823406433623e-06 5.098333386739923 0.2403641027737451 T(ph)QTPPVEENVTQK ddPTM_PC-9_Lapatinib_30min_R1 1 TQTPPVEENVTQK 13 0 Q6P1Q9-2;Q6P1Q9 Q6P1Q9-2 METTL2B Methyltransferase-like protein 2B 1 T(0.943)QT(0.057)PPVEENVTQK 104.82 0.0031707 12377000.0 25087.0 24647.0 27315.0 23859.0 29068.0 27511.0 26839.0 23209.0 27752.0 21814.0 True False 24729.254779607636 24589.931385807173 25069.26613894917 25613.670451290804 27358.277389886804 26334.41866127328 28228.59209576443 24287.374868620074 24626.27751848435 25584.520834672065 0.966570956689352 0.9611253439025902 0.9798606861135886 1.0011393458101914 1.0693292857301024 1.0293106066534166 1.1033465226172665 0.9492995794435946 0.9625459737010549 1.0 14.642983593318908 -5.792238070076292 2.9834049063823214 1.0219275669968602 0.9660811655254671 0.20990526359793094 0.04290998429253942 0.40320762033376245 7.335970018516228 0.01342900636340585 0.02298625290408147 1.6134738457386034e-06 5.792238070076292 -0.05584640147139308 T(ph)QTPPVS(ph)PAPQPTEER ddPTM_PC-9_AZD4547_30min_R2 1 TQTPPVSPAPQPTEER 16 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 T(0.625)QT(0.375)PPVS(0.574)PAPQPT(0.426)EER 123.63 0.0010195 7775500.0 14659.0 19222.0 19124.0 16704.0 12564.0 19321.0 22412.0 18842.0 15628.0 15219.0 True False 19320.25707385843 25435.13559330271 18870.40326460039 12853.150874227384 10819.705470426285 18112.8548156788 24406.624582203 15930.40184608629 16454.06417480566 14686.187442303079 1.3155393222210323 1.7319086858470594 1.2849082403949725 0.8751863562087125 0.7367266360267526 1.233325863968297 1.6618761457381732 1.0847200411046976 1.120376832955997 1.0 13.842172298114061 -5.516856096361708 23.76423791242709 1.1158991589506584 1.5198952229089562 0.3150505483075484 0.24793753272060182 172.21133447337712 679510.310771274 0.07277598756231243 0.1319676364713179 3.041892791014329e-06 5.516856096361708 0.4039960639582978 T(ph)QTPPVSPAPQPT(ph)EER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TQTPPVSPAPQPTEER 16 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 T(0.953)QT(0.047)PPVS(0.419)PAPQPT(0.581)EER;T(0.806)QT(0.194)PPVS(0.34)PAPQPT(0.66)EER 145.82 0.00037889 48757000.0 93009.5 138252.6 129058.5 99691.0 128789.4 87867.0 132905.0 98236.2 99011.3 92710.1 True False 108754.17132863919 151977.40444839763 132135.74409708672 94105.63647258254 103554.04159244362 83259.09983898677 120315.27625112614 95657.60383985759 100459.15295152353 109517.7072372524 0.9930281967375455 1.3876970974124136 1.2065240172608436 0.8592732522122464 0.9455461057827894 0.7602341387463436 1.098591992895565 0.8734441785987253 0.917286852379908 1.0 16.74080462351497 -5.753358847553149 24.908667586097334 0.9183727470184311 1.214944624902375 0.5107105012339372 0.12229552002565382 123.11635950465663 379508.3848205976 0.03171624350475845 0.053720794972399157 1.7645791869077126e-06 5.753358847553149 0.2965718778839439 T(ph)QTPPVSPAPQPTEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQTPPVSPAPQPTEER 16 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 T(0.975)QT(0.025)PPVSPAPQPTEER 145.33 7.2326e-05 81196000.0 23030.0 40150.0 25718.0 21236.0 29387.0 15055.0 20226.0 11264.0 14117.0 16487.0 True False 26928.524136766227 44135.82665789396 26331.214656058142 20046.215768040933 23628.828306344607 14265.489297187196 18310.046856440895 10968.331935194516 14323.434418259887 19475.96258897981 1.382654336787612 2.2661692050521585 1.351985275991302 1.0292798456792986 1.2132303190864946 0.7324664561257226 0.9401356555696696 0.5631727769594703 0.7354416683037065 1.0 14.249407014025282 -5.780821314139603 1.2359205995231128 0.8055070955565984 1.8533525255490904 0.6567160336056126 0.26902420051042114 0.2785868787015173 0.8420461770494659 0.09270572462749396 0.23431648256006055 1.65645135263288e-06 5.780821314139603 1.047845429992492 T(ph)QTPPVSPAPQPTEER ddPTM_PC-9_Lapatinib_30min_R1 1 TQTPPVSPAPQPTEER 16 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 T(0.889)QT(0.111)PPVSPAPQPTEER 146.86 7.326899999999999e-05 359530000.0 341410.0 867760.0 877600.0 800570.0 954930.0 956020.0 830330.0 935520.0 819780.0 728320.0 True False 336541.4307930732 865750.7550350144 805447.1156339677 859446.588423233 898762.8948646148 915133.253191469 873320.4245641083 978987.6744836663 727447.7437338963 854209.1415746026 0.39398013251498465 1.013511460951046 0.942915588738901 1.006131340199633 1.0521578980153319 1.071322242588697 1.0223730724237825 1.146074921042233 0.8516037915409788 1.0 19.70422981193194 -4.761373014023596 8.912695519151379 1.0177686709958238 0.3893075550347089 0.8636196191540275 0.07362020653601382 0.026827315395876017 27.974037220369553 0.017647631193840944 0.10133838826434444 1.7323154788497697e-05 4.761373014023596 -0.6284611159611149 T(ph)QTPPVSPAPQPTEERLPSSPVYEDAASFK ddPTM_PC-9_AZD4547_30min_R2 1 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 T(0.676)QT(0.07)PPVS(0.252)PAPQPT(0.002)EERLPSSPVYEDAASFK 65.668 9.8386e-05 6175100.0 16940.0 18836.0 23209.0 40029.0 36633.0 26649.0 26177.0 27156.0 21479.0 28467.0 True False 22326.56762611103 24924.368641944107 22901.233495508783 30800.932491885047 31547.14028160826 24982.633817246722 28506.70228843155 22959.66418280008 22614.33608975243 27470.37899468045 0.8127506224225919 0.9073179750002951 0.8336700960676054 1.1212416289505707 1.1484057168529513 0.9094389932546809 1.0377251181700762 0.8357971394295705 0.8232262137385007 1.0 14.745589194221472 -5.70306729980126 24.999996934758066 0.9816213690661223 0.8568529201469433 0.2508002185559348 0.10362896649972715 129.5756271836966 55494.059103644075 0.030716510347175426 0.05320253297577682 1.9812199851945636e-06 5.70306729980126 -0.12476844891917904 T(ph)QTPPVSPAPQPTEERLPSSPVYEDAASFK ddPTM_PC-9_Lapatinib_30min_R1 1 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 T(0.924)QT(0.066)PPVS(0.009)PAPQPTEERLPSSPVYEDAASFK 76.35 1.3178000000000001e-06 4938200.0 22700.0 18613.0 17131.0 17251.0 19234.0 14135.0 8882.2 10899.0 12992.0 11503.0 True False 22376.293837329828 18569.90274207931 15722.555307572335 18519.696087649005 18102.693935498948 13530.479000294345 9342.076855061614 11405.407328755671 11528.704148174864 13491.278223215957 1.6585747819524193 1.3764376091602644 1.1653866333077891 1.3727161934723193 1.3418071761612336 1.0029056384747095 0.6924530574861063 0.8453911586471552 0.8545301607030925 1.0 13.719739421603874 -6.853616381151786 3.158105609630731 0.8350364038578971 1.3749554104831267 0.7887937294707519 0.13212383778025463 0.11578880858450687 2.3083629484711325 0.05092900103113836 0.04501458906775325 1.4008241452778738e-07 6.853616381151786 0.5399190066252296 T(ph)QWRY(ph)SY(ph)DLNGNINLLSHGK ddPTM_PC-9_Lapatinib_30min_R1 1 TQWRYSYDLNGNINLLSHGK 20 1 Q9UKZ4;Q9UKZ4-2 Q9UKZ4 TENM1 Teneurin-1;Ten-1 intracellular domain;Teneurin C-terminal-associated peptide 3 T(0.999)QWRY(0.997)S(0.385)Y(0.618)DLNGNINLLSHGK 51.827 0.040324 0.0 1224.9 2147.3 2516.5 2658.3 2333.3 2779.4 2818.8 3409.3 3692.9 3139.7 True False 1207.4327013808506 2142.3280587797194 2309.6030839709174 2853.8002498288415 2196.0598814442997 2660.531541097851 2964.7436715056747 3567.7085242615576 3276.966714039019 3682.3929616127234 0.32789349587830224 0.5817760573389418 0.6272016886973992 0.7749852553973503 0.5963676077858143 0.7225007132135776 0.8051133332079935 0.9688560024563649 0.8899014168775333 1.0 11.84642787482617 -5.008792450274493 0.24534722273512438 1.032719016281303 6.596635562877069e-18 0.8300590617899019 0.07986428433589557 3.9641712158296527 0.22647088317274633 0.1314266963233155 1.2411504120595764 9.799581964285157e-06 5.008792450274493 -1.032719016281303 down T(ph)RELQHQER ddPTM_PC-9_AZD4547_30min_R2 1 TRELQHQER 9 1 Q9BX97 Q9BX97 PLVAP Plasmalemma vesicle-associated protein 1 T(1)RELQHQER 80.165 0.013757 28257000.0 5109.0 0.0 0.0 4694.5 5039.0 5591.3 5189.3 5724.1 4536.9 7011.7 True False 6733.555726198427 0.0 0.0 3612.255554301989 4339.42182947135 5241.675127110645 5651.137646993842 4839.571871732434 4776.71127173508 6766.2225171953805 0.9951720785247697 0.0 0.0 0.5338659119060837 0.6413359623398927 0.7746826406890525 0.8351983152537903 0.715254613550376 0.7059642599095368 1.0 12.724134907725935 -6.2019706741747385 2.466664040896624 0.7794863300300641 0.30074569608029894 0.3472385445158237 0.2738092655054383 0.3179286892585232 3.801057407488907 0.088722582201228 0.11743503207045904 6.281007700165841e-07 6.2019706741747385 -0.4787406339497651 T(ph)RESPLVPIGAVYT(ph)MYSDY(ph)VK ddPTM_PC-9_Lapatinib_30min_R1 1 TRESPLVPIGAVYTMYSDYVK 21 1 K7EID5 K7EID5 HIGD1B 3 T(0.724)RES(0.276)PLVPIGAVY(0.149)T(0.402)MY(0.351)S(0.402)DY(0.697)VK 50.403999999999996 0.012578 9794900.0 27349.0 23151.0 17663.0 25400.0 21570.0 18514.0 19039.0 18059.0 18058.0 19874.0 True False 26958.99824480764 23097.39528189321 16210.816321151711 27268.000731916105 20301.295008251647 17722.199378241934 20024.746261457545 18898.087067620767 16024.117880829861 23309.194419559593 1.1565821520706594 0.9909134938833983 0.695468750629521 1.1698388301671436 0.8709565265462839 0.7603093894729623 0.8590921634191722 0.8107567652257727 0.6874591027214325 1.0 14.50861152442852 -6.510331162100581 24.19985350694024 0.8141092585986696 0.9853492128104546 0.2590974151942034 0.14245825303161155 575.5624188794167 1110059.1888821635 0.04468669723777284 0.048201859125732015 3.0879398910851775e-07 6.510331162100581 0.17123995421178506 T(ph)RHSPT(ph)PQQSNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TRHSPTPQQSNR 12 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 2 T(0.996)RHS(0.133)PT(0.504)PQQS(0.367)NR 71.354 0.036045999999999995 0.0 6239.6 9095.4 12160.0 13803.0 16293.0 16417.0 12573.0 12087.0 14836.0 13187.0 True False 7295.841042282525 9998.331202595482 12449.940517056799 13029.662659929778 13100.503610279135 15556.063619523224 11381.994419362774 11769.729057235107 15052.948433045527 15577.698711765435 0.4683516594638054 0.6418362164781117 0.7992156445838613 0.8364305216719083 0.8409781093265504 0.9986111496542251 0.7306595556868901 0.7555499226818229 0.966314005140979 1.0 13.927194499833046 -4.853318415270705 1.169291069447832 0.8672707201890243 0.30641889140997025 0.6952796022710297 0.08758791252210629 0.8213245833625498 1.033139431309353 0.027398841238849208 0.5490191680535396 1.4017855690063392e-05 4.853318415270705 -0.560851828779054 T(ph)RHSPTPQQSNR ddPTM_PC-9_AZD4547_30min_R2 8 TRHSPTPQQSNR 12 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 T(0.998)RHS(0.002)PTPQQSNR;T(1)RHSPTPQQSNR;T(0.987)RHS(0.013)PTPQQSNR;T(0.934)RHS(0.064)PTPQQS(0.003)NR;T(0.946)RHS(0.054)PTPQQSNR;T(1)RHSPTPQQSNR;T(1)RHSPTPQQSNR;T(0.773)RHS(0.218)PT(0.009)PQQSNR 100.09 0.0022657 4103331040.0 13487.410000000002 13224.05 18058.4 35301.93000000001 23736.33 21235.489999999998 20269.3 22994.93 21929.56 25658.06 True False 17776.1258244443 17498.46555210772 17818.93381685104 27163.61544788157 20440.950298379765 19907.631453330523 22073.228433162923 19441.59193942389 23088.711771515955 24759.77912910564 0.7179436347858247 0.7067294688238114 0.7196725675110934 1.0970863393506678 0.8255707852559557 0.8040310597895717 0.8914953690849117 0.7852086174940831 0.9325087938435885 1.0 14.595710824523064 -5.5779560617165975 24.999999098325024 0.8896451852976844 0.7125497798894176 0.48371878295595316 0.08913809702544613 75.39051785078176 34219.857281190954 0.023889714783115405 0.04137820364858965 2.6426761076638023e-06 5.5779560617165975 -0.17709540540826685 T(ph)RHSPTPQQSNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 TRHSPTPQQSNR 12 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 T(0.992)RHS(0.002)PTPQQS(0.006)NR;T(0.957)RHS(0.042)PT(0.001)PQQSNR;T(1)RHSPTPQQSNR;T(0.996)RHS(0.004)PTPQQSNR;T(1)RHSPTPQQSNR;T(1)RHSPTPQQSNR;T(0.499)RHS(0.475)PT(0.024)PQQS(0.002)NR 86.911 0.0063902 1907663800.0 12050.14 19964.199999999997 21079.180000000004 19323.05 27109.670000000002 23251.62 15794.67 21046.710000000003 25115.14 19758.19 True False 14089.990700886325 21946.113837198656 21581.787594435333 18240.442154673343 21797.724771894416 22032.26411506234 14298.484514091824 20494.256163332557 25482.401409323196 23340.193441254018 0.6036792598291894 0.940271291771245 0.9246618991721515 0.7815034695656458 0.9339136295831519 0.9439623613453049 0.6126120826753353 0.8780671083517568 1.0917819286057333 1.0 14.510528897560494 -10.340229873407429 0.0262364826984771 1.9368087179016487 1.6490645934947683e-09 0.18992347414352417 0.13609096643966706 1444.7812094073474 7.770386692549492 329.55515485566525 246.8451668633941 4.5684631544574035e-11 10.340229873407429 -1.936808716252584 T(ph)RHSPTPQQSNR ddPTM_PC-9_Lapatinib_30min_R1 3 TRHSPTPQQSNR 12 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 T(1)RHSPTPQQSNR;T(0.993)RHS(0.006)PTPQQSNR;T(0.993)RHS(0.006)PTPQQSNR 103.43 0.0015115 989931900.0 8174.8 7271.43 9535.81 7368.4 10686.94 9229.619999999999 7944.13 8708.2 11189.44 4256.4 True False 8058.225852925279 7254.593450590325 8751.812511091077 7910.296716261837 10058.355200532442 8834.89066789506 8355.438180473384 9112.814762847062 9929.167437173159 4992.113068703504 1.6141913738780904 1.4532109651263183 1.7531278620185582 1.5845588045376968 2.0148492356052916 1.7697697440554088 1.6737277512513085 1.8254423802972357 1.9889708627436702 1.0 12.285434895506976 -5.27395805804059 23.33139204434833 1.7392745854923404 1.5337011739630826 0.04350848131154017 0.2710265700796662 671.0678423593303 1250691.2183412015 0.06599188387223182 0.1391664828461406 5.321596500664479e-06 5.27395805804059 -0.2055734115292578 T(ph)RLSPPR ddPTM_PC-9_AZD4547_30min_R2 1 TRLSPPR 7 1 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 T(0.956)RLS(0.044)PPR 75.043 0.024000999999999998 619060000.0 23209.0 16312.0 28522.0 45784.0 24950.0 35149.0 32591.0 37961.0 30024.0 25853.0 True False 30588.97922281056 21584.535001454242 28143.77964405628 35229.20615574872 21486.123168348913 32951.12747354142 35491.53586286714 32094.999706999348 31611.00734478919 24947.89433904077 1.2261146695231149 0.8651846407605137 1.1281024066233236 1.412111406156583 0.86123994579877 1.3207979409298864 1.4226265102993765 1.2864813066317236 1.2670811778820694 1.0 14.606630433395756 T(ph)RLSPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TRLSPPR 7 1 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 T(0.95)RLS(0.05)PPR 76.17 0.022813 226880000.0 4487.8 7663.3 5260.5 5808.4 6330.2 7229.7 5921.5 4818.7 5377.9 4107.5 True False 5247.495901909658 8424.061779014668 5385.930270557349 5482.974179086879 5089.842751720922 6850.561804840532 5360.572652052542 4692.21423083468 5456.54161351277 4852.157235047892 1.0814768870238114 1.7361477320162566 1.1100073657246576 1.130007523145066 1.0489855347135477 1.4118589882780077 1.1047813152740158 0.9670367227471693 1.1245599326623867 1.0 12.244410586676235 -5.668795939831622 0.2969864290610998 0.9973774893761664 1.519807839994024 0.18628435996744241 0.19826668901590508 7.357952755357891 0.8055698470742247 0.24812677817251813 1.3461961163942826 2.1438977089290546e-06 5.668795939831622 0.5224303506178576 T(ph)RLSPPR ddPTM_PC-9_Lapatinib_30min_R1 1 TRLSPPR 7 1 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 T(0.999)RLS(0.001)PPR 66.29899999999999 0.03937 560590000.0 18401.0 14837.0 13488.0 13244.0 14584.0 14177.0 13142.0 14441.0 15141.0 13407.0 True False 18138.598365669888 14802.64583808257 12379.068705185664 14218.007940688858 13726.197793247191 13570.682758201134 13822.428455700147 15111.981579462385 13435.661138201624 15724.382086295438 1.1535333004581818 0.9413817189664829 0.7872531103129721 0.9042013773679884 0.8729244632900544 0.8630344062949629 0.8790443007453415 0.9610540812686821 0.8544476383533985 1.0 13.94071570485416 -4.793907656721129 3.7686126860869305 0.8861454614076067 1.1773489684245748 0.6672577179677107 0.055436202434206897 0.13290132497549975 3.330715298441661 0.013228122305752628 0.1054161143344988 1.6072829704593013e-05 4.793907656721129 0.29120350701696807 T(ph)RMEERR ddPTM_PC-9_Lapatinib_30min_R1 1 TRMEERR 7 2 A2A2L6;A2A2L5;A0A0A0MQR2;Q9BY42 A2A2L6 RTFDC1 Protein RTF2 homolog 1 T(1)RMEERR 56.258 0.034625 0.0 4158.5 4333.1 6927.6 3164.8 6058.9 3653.0 3250.1 3622.9 3258.5 4072.2 True False 4099.199027424501 4323.0669731748685 6358.039469309325 3397.54994946331 5702.527414255718 3496.7697055589133 3418.374275138565 3791.233160046694 2891.4934164738142 4776.074344134574 0.8582778935295817 0.9051506868782231 1.331227072944863 0.7113687318615111 1.193977941582695 0.7321430642831689 0.7157288661841329 0.7937969317212684 0.6054121456515463 1.0 12.221609578358501 -6.79306813358711 24.977730133757643 0.7531728842090413 0.997097488573275 0.27547295657855164 0.18601668671200436 245.48165253548095 193859.07101490576 0.062290541897318814 0.05493996478913304 1.6103929714636878e-07 6.79306813358711 0.2439246043642337 T(ph)RNSGIWESPELDR ddPTM_PC-9_AZD4547_30min_R2 1 TRNSGIWESPELDR 14 1 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 T(0.562)RNS(0.434)GIWES(0.004)PELDR 66.215 0.026771 15176000.0 7156.5 5727.3 8257.2 10507.0 10669.0 9394.8 10773.0 11868.0 12619.0 9588.1 True False 9432.118135552762 7578.537721544198 8147.704132841364 8084.773481531795 9187.793510345267 8807.341670842045 11731.776129933658 10034.073299509175 13286.014577800917 9252.423537390503 1.0194213545711657 0.81908677125708 0.8806021579011387 0.8738006262748296 0.9930148001997471 0.9518956449896816 1.2679679094373166 1.0844805427421154 1.4359496756833532 1.0 13.175615592714376 -7.175615729220139 4.673621996884913 1.2038750006667167 0.913255869434147 0.5562666808680264 0.11990501454944942 0.15844583877142857 6.0692480812961715 0.044726559519992964 0.034051313501097004 6.673970317232718e-08 7.175615729220139 -0.29061913123256966 T(ph)RS(ph)RYY(ph)QPY(ph)EIPAVNGRR ddPTM_PC-9_Lapatinib_30min_R1 1 TRSRYYQPYEIPAVNGRR 18 3 Q96GV9 Q96GV9 C5orf30 UNC119-binding protein C5orf30 4 T(0.982)RS(0.62)RY(0.407)Y(0.992)QPY(0.999)EIPAVNGRR 47.548 0.019791999999999997 7443800.0 14746.0 29990.0 21879.0 24634.0 24889.0 33500.0 31904.0 31473.0 26587.0 25518.0 True False 14535.719335914782 29920.559997580094 20080.193075382358 26445.666536615023 23425.077953656713 32067.28309231416 33555.83301252909 32935.35047783531 23592.49208647822 29928.752299402327 0.4856774245214712 0.9997262731924045 0.6709331840667262 0.8836207494404349 0.782694771880768 1.0714540576739826 1.1211905086066416 1.100458520567629 0.7882885277161842 1.0 14.869244515084914 -6.7549412847263595 24.88019369120439 1.0291140009807294 0.7790131385273116 0.4033508882259004 0.152185105631217 146.87393328656725 562356.945909325 0.048561789503616816 0.04745060809470541 1.7581612958725923e-07 6.7549412847263595 -0.2501008624534178 T(ph)RS(ph)S(ph)GASHQPS(ph)PTELRPT(ph)LTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TRSSGASHQPSPTELRPTLTPK 22 2 Q8TBP0 Q8TBP0 TBC1D16 TBC1 domain family member 16 5 T(0.792)RS(0.792)S(0.792)GAS(0.792)HQPS(0.826)PT(0.17)ELRPT(0.694)LT(0.142)PK 42.711000000000006 0.031449 1726400.0 0.0 802.83 883.78 928.89 714.75 2233.3 1291.0 1054.5 1148.7 932.02 True False 0.0 882.5296566813697 904.8526669543144 876.8473048020121 574.6998683758065 2116.181816500045 1168.7071339694057 1026.8204923351057 1165.497564373106 1100.9878481337394 0.0 0.8015798341256233 0.8218552715982383 0.7964186946189615 0.5219856598326383 1.9220755434196108 1.0615077504719566 0.9326356272466102 1.058592577882413 1.0 10.104582830281952 -5.0658895610486345 0.780156792478564 1.112395518234719 1.5457877353515849e-15 0.41732175156654305 0.3486072292652718 2.142075439572412 1.3126521060712173 0.14753726352709673 1.930344341755359 8.592319921970651e-06 5.0658895610486345 -1.1123955182347174 T(ph)RSEGGGTGESSQGGTSK ddPTM_PC-9_AZD4547_30min_R2 3 TRSEGGGTGESSQGGTSK 18 1 F5H0R1;Q9H6E5 F5H0R1 TUT1 Speckle targeted PIP5K1A-regulated poly(A) polymerase 1 T(0.975)RS(0.025)EGGGTGESSQGGTSK;T(0.725)RS(0.252)EGGGT(0.015)GES(0.004)S(0.004)QGGTSK;T(0.477)RS(0.477)EGGGT(0.046)GESSQGGTSK 93.115 0.00077033 14599300.0 37259.1 42150.4 56679.4 72166.0 60753.4 57348.9 51924.3 55998.1 46208.9 50418.5 True False 49106.71876257578 55774.69250400305 55927.79412233793 55529.243653585494 52318.8390900188 53762.86421711513 56545.462109302294 47344.88035332362 48651.40811666097 48653.363661197036 1.0093180628689054 1.1463686846483248 1.1495154684843 1.141323836112738 1.075338582021722 1.1050184441819615 1.1622107466826495 0.97310600522946 0.9999598065911808 1.0 15.570251929048679 -7.770132513633077 24.99996724121497 0.9898996385084163 1.1148017894796562 0.6278473621453222 0.04291582161607599 121.90579177696178 350573.9133437093 0.022893587269765786 0.01126749446011217 1.6977255567536588e-08 7.770132513633077 0.12490215097123991 T(ph)RSEGGGTGESSQGGTSK ddPTM_PC-9_Lapatinib_30min_R1 3 TRSEGGGTGESSQGGTSK 18 1 F5H0R1;Q9H6E5 F5H0R1 TUT1 Speckle targeted PIP5K1A-regulated poly(A) polymerase 1 T(0.934)RS(0.008)EGGGT(0.036)GES(0.019)S(0.002)QGGTSK;T(0.843)RS(0.155)EGGGT(0.002)GESSQGGTSK;T(0.762)RS(0.209)EGGGT(0.009)GES(0.016)S(0.004)QGGTSK 98.135 0.00052597 9175100.0 14785.900000000001 17481.2 18579.5 17650.7 26366.0 24236.5 29848.2 30385.6 32316.9 26079.9 True False 14575.050354598017 17440.723355441736 17051.965228944016 18948.791359009123 24815.203717550434 23199.961393040972 31393.593747635747 31797.42590408646 28677.030409956293 30587.775965717618 0.47649918617599213 0.5701860565145067 0.5574764653715144 0.6194890200662736 0.8112784579487895 0.7584716659048107 1.0263444384718026 1.0395468418404987 0.937532380323994 1.0 14.900667592039689 -6.568245385464145 0.8532101147011304 1.0171894515339688 0.5100005329714911 0.9228042807478956 0.056540681486317086 0.15058840642760166 0.2417654280703246 0.033360561944468556 0.03869939073365756 2.702431002624768e-07 6.568245385464145 -0.5071889185624777 T(ph)RSEITFGQVK ddPTM_PC-9_AZD4547_30min_R2 1 TRSEITFGQVK 11 1 F5H5A3;Q8IVH8-3;Q8IVH8-2;Q8IVH8;H7C1A4 F5H5A3 MAP4K3 Mitogen-activated protein kinase kinase kinase kinase;Mitogen-activated protein kinase kinase kinase kinase 3 1 T(0.869)RS(0.131)EITFGQVK 64.798 0.033367 3798000.0 39594.0 35887.0 43367.0 75459.0 76150.0 67091.0 39478.0 52621.0 49232.0 67532.0 True False 52184.06839363874 47486.77094146571 42791.92524450558 58063.09337992834 65577.88694468017 62895.78916405498 42991.4655209803 44489.63356028587 51834.30301087998 65167.72523514103 0.800765535475512 0.7286854155200579 0.6566429177956096 0.8909792872226635 1.006293939339745 0.9651370971920786 0.6597048671847394 0.6826942846287243 0.7953983789344984 1.0 15.99187001622145 -11.908565318452947 2.0464643016059245 2.2406240404575044 0.7985012578311386 0.2103767106258686 0.11712641948161903 8447730.700108692 744019.334594533 48573473.771720976 0.033219499242941396 1.2343396549253987e-12 11.908565318452947 -1.4421227826263658 T(ph)RSEITFGQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TRSEITFGQVK 11 1 F5H5A3;Q8IVH8-3;Q8IVH8-2;Q8IVH8;H7C1A4 F5H5A3 MAP4K3 Mitogen-activated protein kinase kinase kinase kinase;Mitogen-activated protein kinase kinase kinase kinase 3 1 T(0.5)RS(0.5)EITFGQVK;T(0.831)RS(0.169)EITFGQVK 105.58 0.0018312 8418300.0 20570.3 27281.0 34089.0 40531.0 59342.0 52788.0 52797.0 46301.0 50997.0 47787.0 True False 24052.445508055665 29989.27738615207 34901.81104325241 38260.179473274955 47714.36109011137 50019.70435203703 47795.68594282163 45085.64780996461 51742.73464815464 56450.40481831611 0.42608101014452815 0.5312499969251175 0.6182738840506604 0.6777662551121496 0.8452439135499307 0.8860822967173382 0.8466845560567825 0.7986771388986736 0.9166052008783115 1.0 15.78469630646948 -4.71923094188029 0.40089043873228 0.9323568403426096 9.660775854906657e-13 0.9283338860738961 0.04672904704396633 1.603548238173686 0.1958961525943552 0.04195111856343137 0.7306901878753564 1.9088379386148115e-05 4.71923094188029 -0.9323568403416435 down T(ph)RSEITFGQVK ddPTM_PC-9_Lapatinib_30min_R1 1 TRSEITFGQVK 11 1 F5H5A3;Q8IVH8-3;Q8IVH8-2;Q8IVH8;H7C1A4 F5H5A3 MAP4K3 Mitogen-activated protein kinase kinase kinase kinase;Mitogen-activated protein kinase kinase kinase kinase 3 1 T(0.9)RS(0.1)EITFGQVK 73.415 0.017874 4546800.0 93678.0 63249.0 68083.0 58838.0 66883.0 60226.0 43521.0 46125.0 56524.0 37993.0 True False 92342.13454155884 63102.550826506995 62485.47854798005 63165.14279781418 62949.073437037325 57650.27437366309 45774.304430111544 48268.13588759108 50157.671895892534 44560.039427509706 2.072308187513637 1.4161242143683974 1.402276105469598 1.4175288803451636 1.4126799312968048 1.293766233475816 1.0272500881552675 1.0832157356169694 1.1256200070803137 1.0 15.443462888750005 -1.5228787452803376 0.3077106137884921 1.0416778321229412 8.841184769336664 0.8222380223072562 0.12524700512680031 24.25918809684728 0.3462805349084749 0.1309723313461716 105.05824408814253 0.029999999999999995 1.5228787452803376 7.799506937213723 up T(ph)RSEPLPPSATAPPPPGPMQPR ddPTM_PC-9_AZD4547_30min_R2 3 TRSEPLPPSATAPPPPGPMQPR 22 1 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;Q8WUI4-10 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 T(0.496)RS(0.496)EPLPPS(0.006)AT(0.002)APPPPGPMQPR;T(0.781)RS(0.208)EPLPPS(0.006)AT(0.005)APPPPGPMQPR;T(0.498)RS(0.498)EPLPPS(0.004)AT(0.001)APPPPGPMQPR 71.742 0.00097607 137782000.0 45274.0 37707.5 66608.3 87577.0 62877.8 65422.2 60113.8 58552.6 57879.2 53997.6 True False 59670.19024229936 49895.71196464786 65725.03042090997 67387.47570116201 54148.30281983201 61331.33949186379 65463.81174413864 49504.64107489395 60938.576349271294 52107.16045959031 1.145143771335885 0.9575596045641854 1.2613435435976303 1.293247897348422 1.039172012871909 1.1770232526761257 1.2563304384031166 0.9500544769328845 1.1694856486476526 1.0 15.6691940178828 -7.762412651108233 24.999999831794188 1.0448275710209858 1.1583772200843399 0.2047523584453932 0.10953470936344428 46.87302937465469 1203883.831653359 0.056680729924634625 0.02970508250743934 1.728173530083966e-08 7.762412651108233 0.11354964906335407 T(ph)RSEPLPPSATAPPPPGPMQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TRSEPLPPSATAPPPPGPMQPR 22 1 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;Q8WUI4-10 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 T(0.496)RS(0.496)EPLPPS(0.004)AT(0.004)APPPPGPMQPR;T(0.48)RS(0.48)EPLPPS(0.029)AT(0.01)APPPPGPMQPR 54.117 0.0095986 60142000.0 17147.8 33760.6 26404.4 34537.9 24564.6 34202.4 29674.5 26662.4 22550.0 23845.4 True False 20050.583855511926 37112.1292519675 27033.98103524463 32602.853436382575 19751.34296845655 32408.76593411593 26863.516535224724 25962.540251147948 22879.751089591293 28168.38225991747 0.7118116926453082 1.3175101398981168 0.9597278532290067 1.1574272578221572 0.701188402876865 1.1505369969447043 0.9536762277417145 0.9216908522322792 0.8122493822496971 1.0 14.781789090134406 T(ph)RSEPLPPSATAPPPPGPMQPR ddPTM_PC-9_Lapatinib_30min_R1 3 TRSEPLPPSATAPPPPGPMQPR 22 1 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;Q8WUI4-10 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 T(0.491)RS(0.491)EPLPPS(0.016)AT(0.002)APPPPGPMQPR;T(0.602)RS(0.394)EPLPPS(0.004)ATAPPPPGPMQPR;T(0.496)RS(0.496)EPLPPS(0.008)ATAPPPPGPMQPR 112.58 4.4764e-06 93726000.0 81276.0 71554.0 73129.0 63762.0 72597.0 73609.0 61409.0 67469.0 73267.0 49982.0 True False 80116.98933580691 71388.32110926458 67116.61590610351 68451.27018379667 68326.98719119346 70460.91466095975 64588.45754345534 70603.85604769397 65014.89892428631 58621.32210317138 1.3666868378506365 1.2177876333738047 1.1449181543190161 1.1676855404817543 1.1655654417165902 1.2019673411144007 1.101791212244958 1.2044057266984491 1.1090657220228242 1.0 15.839137885451004 -1.5228787452803627 0.06939158812746656 0.8400433980205398 1.9361020447816903 0.6472554045402155 0.05347091397988573 184.23981234900546 0.948438946126072 2.6433174448118497 19.765703583771867 0.029999999999998264 1.5228787452803627 1.0960586467611506 T(ph)RSLSSLR ddPTM_PC-9_AZD4547_30min_R2 2 TRSLSSLR 8 1 H0Y9X0;A0A286YEZ9;A0A2C9F2R7;O94915 H0Y9X0 FRYL Protein furry homolog-like 1 T(0.938)RS(0.045)LS(0.013)S(0.004)LR;T(0.886)RS(0.088)LS(0.026)SLR 83.883 0.010398000000000001 11290400.0 15054.7 11372.400000000001 19253.2 31664.0 27391.0 17167.4 17112.6 18165.7 15412.6 22285.9 True False 19841.78144278713 15048.305900597006 18997.88998818261 24364.354003923345 23588.232453075947 16093.919764126304 18635.588248501117 15358.608471258338 16227.278570553473 21505.67742430002 0.922629920058561 0.699736427906865 0.8833895167941199 1.1329265999495186 1.0968374530914693 0.7483567918647016 0.866542721757935 0.7141652954351536 0.7545578895467715 1.0 14.392429956137077 -6.794923448930831 24.99998856586322 0.8019734850994744 0.9401454117101105 0.1867607431470799 0.13388747401461432 342.9441058522052 256047.7515674817 0.0512941477258497 0.04523978652490233 1.6035280122085826e-07 6.794923448930831 0.13817192661063604 T(ph)RSLSSLR ddPTM_PC-9_Lapatinib_30min_R1 3 TRSLSSLR 8 1 H0Y9X0;A0A286YEZ9;A0A2C9F2R7;O94915 H0Y9X0 FRYL Protein furry homolog-like 1 T(0.892)RS(0.08)LS(0.022)S(0.006)LR;T(0.902)RS(0.07)LS(0.021)S(0.006)LR;T(0.618)RS(0.272)LS(0.084)S(0.026)LR 90.149 0.0069862 86862700.0 82178.0 47549.7 62680.7 40577.299999999996 42943.8 47548.4 33878.7 34767.2 44261.8 28925.300000000003 True False 81006.12665040033 47439.60159109483 57527.334800499055 43561.49000390471 40417.93011475923 45514.865772734054 35632.773316247796 36382.61103590368 39276.569986582974 33924.999564460464 2.3878003740716816 1.398367050851554 1.6957210181002977 1.2840527800489452 1.1913907334902578 1.3416320223159275 1.0503396838235004 1.0724424908767807 1.1577471036353018 1.0 15.050061176671818 -1.5228787452803376 0.5195133245900979 1.1101733783538184 42.73276487076531 0.831061582238062 0.1620347341827619 44.74249589777574 0.44977368949034474 0.08180086198966456 2051.481140120943 0.029999999999999995 1.5228787452803376 41.62259149241149 up T(ph)RSNPEGAEDR ddPTM_PC-9_Lapatinib_30min_R1 1 TRSNPEGAEDR 11 1 M0R3H9;M0QXG9;M0R3F4;M0R2A4;M0R2K3;M0R193;M0R0I0;J3KQS6;Q9NWV8-3;Q9NWV8;M0R2I2 M0R3H9 BABAM1 BRISC and BRCA1-A complex member 1 1 T(0.575)RS(0.425)NPEGAEDR 67.207 0.029036000000000003 110360000.0 7453.8 5431.0 8954.9 9108.0 8091.2 8838.5 6823.5 7494.2 9372.1 7943.3 True False 7347.507445140487 5418.424853179647 8218.662688913633 9777.832703397318 7615.291523911252 8460.497958549811 7176.787442358084 7842.4078909221735 8316.515405411763 9316.28882121806 0.788673213780832 0.5816076505527673 0.8821820412217621 1.0495416029962576 0.817416856652968 0.908140368005856 0.7703483200319838 0.8417952729268022 0.8926854421334286 1.0 13.185539650969133 -5.285024395746847 22.239717405153364 0.8883419428469413 0.6851405332609894 0.46309096514852577 0.09025473710928965 147.57064082183263 139153.23747705884 0.02341024894563189 0.048811194550957206 5.187708970460479e-06 5.285024395746847 -0.2032014095859519 T(ph)RSPDVISSASTALSQDIPEIASEALSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TRSPDVISSASTALSQDIPEIASEALSR 28 1 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 T(0.44)RS(0.44)PDVIS(0.02)S(0.02)AS(0.036)T(0.043)ALS(0.001)QDIPEIASEALSR;T(0.554)RS(0.425)PDVIS(0.008)S(0.008)AS(0.003)T(0.003)ALSQDIPEIASEALSR 84.365 3.6576e-07 5152100.0 7146.0 9132.1 4671.610000000001 8996.7 9875.1 6337.6 8123.5 7781.9 8285.7 5937.2 True False 8355.67666006649 10038.67453605363 4782.998899579582 8492.64406669494 7940.145043998491 6005.245099292829 7353.983270953107 7577.633370604599 8406.862687495639 7013.567361150655 1.19135900887614 1.4313221815847323 0.6819637786718108 1.2108879304043108 1.1321121813102284 0.8562326117457579 1.0485367705581718 1.080424979244999 1.1986571532858847 1.0 12.775932723925012 -5.219327772296561 24.999997393601955 1.034094000224239 1.3113406251228137 0.33631530351706074 0.15996374441981973 553.076216262291 328337.769051965 0.03930292456679948 0.10398360377972134 6.034929870538479e-06 5.219327772296561 0.27724662489857477 T(ph)RSPDVISSASTALSQDIPEIASEALSR ddPTM_PC-9_Lapatinib_30min_R1 2 TRSPDVISSASTALSQDIPEIASEALSR 28 1 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 T(0.487)RS(0.366)PDVIS(0.014)S(0.022)AS(0.047)T(0.065)ALSQDIPEIASEALSR;T(0.481)RS(0.481)PDVIS(0.01)S(0.01)AS(0.014)T(0.004)ALSQDIPEIASEALSR 84.87799999999999 3.4604e-07 14478450.0 27763.6 25372.62 23670.1 19146.82 18481.36 23538.3 21918.86 19432.0 24971.0 20295.75 True False 27367.685972779305 25313.87125727912 21724.035747228292 20554.94101471912 17394.32274055177 22531.62177945728 23053.711320994327 20334.881660003673 22158.503023712623 23803.84334511303 1.1497171097959666 1.0634363069136943 0.9126272355379231 0.8635135392511766 0.7307358937111663 0.9465539431086477 0.9684869366159433 0.8542688407575351 0.9308792156986616 1.0 14.538906908010565 -5.144087276054726 2.505927304408445 0.8902906844140659 1.1447500944897855 0.5822938785868547 0.07122683648851287 0.2191263834888576 2.509328598140388 0.01985711885637264 0.08294001259133527 7.176500574342629e-06 5.144087276054726 0.2544594100757196 T(ph)RSPSPTLGESLAPHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TRSPSPTLGESLAPHK 16 1 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 T(0.333)RS(0.333)PS(0.333)PT(0.002)LGESLAPHK;T(0.36)RS(0.36)PS(0.14)PT(0.14)LGESLAPHK 83.85600000000001 0.0032185000000000004 10814100.0 26875.0 28022.0 60301.0 67577.0 71083.0 73783.0 63434.0 52718.0 67224.0 51817.0 True False 31424.406694554567 30803.83896905365 61738.804532815964 63790.87977759 57154.79642358511 69913.68959245176 57425.0722976106 51334.20835933814 68207.02382468682 61211.01191685367 0.5133783237767755 0.503240152456493 1.0086225108756448 1.042147119937189 0.9337338925424343 1.1421750335939458 0.9381493705023906 0.8386433543864339 1.114293354884187 1.0 15.901503597969361 -5.26105573590936 24.984846100663212 0.9981479622978867 0.5083091899683893 0.8487637528918368 0.08338149711617872 11.055201851516014 719906.5008928819 0.021421695033383835 0.05006260016256566 5.482066053936753e-06 5.26105573590936 -0.48983877232949746 T(ph)RSYDNLTTACDNTVPLASR ddPTM_PC-9_AZD4547_30min_R2 3 TRSYDNLTTACDNTVPLASR 20 1 G5E953;Q13615-3;Q13615-2;Q13615 G5E953 MTMR3 Myotubularin-related protein 3 1 T(0.489)RS(0.489)Y(0.022)DNLTTACDNTVPLASR;T(0.483)RS(0.415)Y(0.102)DNLTTACDNTVPLASR;T(0.366)RS(0.366)Y(0.267)DNLTTACDNTVPLASR 124.2 6.5425e-06 77946500.0 86743.0 62807.0 84706.0 151436.0 128052.0 108394.0 91441.0 113344.0 79188.0 126015.0 True False 114325.46963351518 83108.13449217367 83582.74309408283 116524.76986287694 110274.19013841361 101616.10604475351 99579.07185531098 95829.28918601004 83373.71601449396 121603.25320598067 0.9401514072971565 0.6834367691742499 0.6873396960236264 0.9582372740102486 0.9068358553831036 0.8356364107515164 0.8188849330094525 0.7880487294504139 0.6856207693166673 1.0 16.89182229961103 -11.90468477385058 2.414646705715918 2.5749835967064945 0.8114998595866366 0.249683750388084 0.09799008088257233 9291044.299454773 2268238.4716716423 78658499.65160511 0.025946373430065978 1.2454182519823514e-12 11.90468477385058 -1.763483737119858 T(ph)RSYDNLTTACDNTVPLASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TRSYDNLTTACDNTVPLASR 20 1 G5E953;Q13615-3;Q13615-2;Q13615 G5E953 MTMR3 Myotubularin-related protein 3 1 T(0.358)RS(0.358)Y(0.285)DNLTTACDNTVPLASR;T(0.458)RS(0.458)Y(0.084)DNLTTACDNTVPLASR;T(0.494)RS(0.286)Y(0.22)DNLTTACDNTVPLASR 129.2 2.1866e-05 41733300.0 50189.7 50599.4 45195.9 66269.3 72795.2 60563.5 65591.0 65528.6 65891.0 54785.3 True False 58685.824918239494 55622.57403221516 46273.54166240526 62556.44596896943 58531.50312471554 57387.44344405157 59377.74564228301 63808.54368329079 66854.53122147506 64717.44120980386 0.9068007606788593 0.8594680659869639 0.7150088260194597 0.9666087657293368 0.9044162134742864 0.8867384490374152 0.917492171079348 0.9859559106552658 1.033021855804575 1.0 15.981866947346639 -7.442704622390217 0.7522143185000925 1.0246004385041976 0.8522648600976916 0.49245073461100364 0.060807759630619074 0.5901353713396412 0.6374373407969711 0.05491972030910798 0.030448018298772073 3.6082396754159906e-08 7.442704622390217 -0.17233557840650593 T(ph)RSYDNLTTACDNTVPLASR ddPTM_PC-9_Lapatinib_30min_R1 3 TRSYDNLTTACDNTVPLASR 20 1 G5E953;Q13615-3;Q13615-2;Q13615 G5E953 MTMR3 Myotubularin-related protein 3 1 T(0.748)RS(0.208)Y(0.044)DNLTTACDNTVPLASR;T(0.364)RS(0.364)Y(0.272)DNLTTACDNTVPLASR;T(0.455)RS(0.304)Y(0.241)DNLTTACDNTVPLASR 124.86 8.5671e-06 70285300.0 135620.0 114109.0 161798.6 132172.6 119575.9 129197.0 104333.1 96328.0 139762.4 113918.3 True False 133686.03393033828 113844.787621336 148496.14366865775 141893.0139188682 112542.68065726457 123671.54548291684 109734.95741222109 100803.75054265294 124020.88674868197 133608.92636840686 1.0005771138503037 0.852074713237541 1.1114238225311504 1.062002500698338 0.842329054773966 0.9256233759555169 0.8213145662861115 0.754468681715932 0.9282380310931675 1.0 17.027656871449643 -6.270673337260377 24.90959614741387 0.8658663830721652 1.0029809285135018 0.3275590739860771 0.08855684254407614 721.1719266608196 1945436.0820997003 0.027860527464166326 0.03202944008416972 5.361998186215781e-07 6.270673337260377 0.1371145454413366 T(ph)RTPASINATPANINLADLTR ddPTM_PC-9_AZD4547_30min_R2 1 TRTPASINATPANINLADLTR 21 1 Q7KZ85;Q7KZ85-2 Q7KZ85 SUPT6H Transcription elongation factor SPT6 1 T(0.519)RT(0.37)PAS(0.11)INATPANINLADLTR 69.03 0.0022904 5863100.0 14909.0 13210.0 21704.0 27428.0 25352.0 24667.0 17394.0 23700.0 17817.0 21447.0 True False 19649.751873535402 17479.87416437044 21416.190778858327 21104.898358375754 21832.312407374004 23124.56859056719 18942.032303357097 20037.70957182066 18758.770245873584 20696.14705795873 0.9494400971594887 0.8445955720849274 1.0347911965876133 1.0197501157714204 1.0548974331421925 1.1173368900891438 0.91524438101018 0.9681855040798587 0.9063894933361462 1.0 14.337074589894348 -5.268694240271586 24.9826998202773 1.004471407126348 0.8970178330384422 0.3012755485035786 0.06391283632423878 629.9687961136935 2169354.0949204243 0.01773074326624963 0.03814876600315613 5.386488782190319e-06 5.268694240271586 -0.1074535740879059 T(ph)RTPASINATPANINLADLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TRTPASINATPANINLADLTR 21 1 Q7KZ85;Q7KZ85-2 Q7KZ85 SUPT6H Transcription elongation factor SPT6 1 T(0.423)RT(0.423)PAS(0.153)INATPANINLADLTR;T(0.491)RT(0.475)PAS(0.034)INATPANINLADLTR 86.439 0.00032551 20410500.0 38616.9 45943.0 49497.1 50780.0 66876.0 62601.0 54344.0 55210.0 55493.0 53564.0 True False 45153.97845145842 50503.91741329072 50677.298582797055 47934.961230981244 53772.127873382815 59318.093357237805 49196.14290351152 53760.79599983041 56304.480142558314 63274.72918760934 0.7136178855475942 0.7981688434184648 0.8009089763551426 0.7575688090083209 0.8498199607294826 0.9374689408999267 0.7775006473381362 0.8496408706930985 0.8898415033214245 1.0 15.949341807242515 -12.082479777722252 0.029449394244539677 2.0181079752189746 3.41912562529596e-11 0.6720325275154664 0.04710668847225033 600.2564755522835 2.1202899637233044 95.43595591120739 54.532136762876796 8.270280170030946e-13 12.082479777722252 -2.0181079751847832 T(ph)RTPASINATPANINLADLTR ddPTM_PC-9_Lapatinib_30min_R1 2 TRTPASINATPANINLADLTR 21 1 Q7KZ85;Q7KZ85-2 Q7KZ85 SUPT6H Transcription elongation factor SPT6 1 T(0.632)RT(0.361)PAS(0.007)INATPANINLADLTR;T(0.496)RT(0.496)PAS(0.008)INATPANINLADLTR 142.84 6.5846e-05 14803500.0 37857.0 29803.0 33800.0 31805.0 33020.0 36325.0 33819.0 29381.0 39191.0 36845.0 True False 37317.15223787647 29733.99298459087 31021.094471773078 34144.045798369756 31077.828519817755 34771.46442771083 35569.98234236211 30746.148520613846 34776.8968804742 43213.60915712355 0.8635509267969792 0.6880701141272151 0.7178547470770421 0.790122520760136 0.7191676216355728 0.804641526267401 0.8231199160669637 0.7114922618201515 0.8047672378862482 1.0 15.399198107946196 -14.522878745280332 0.3286283102262164 3.356570809182255 0.7564182955477322 0.6204540212764542 0.054327209608559024 223.57289009678396 1.940392411614918 367.6998843930997 0.045027908999279324 3.000000000000038e-15 14.522878745280332 -2.600152513634523 T(ph)S(ph)FNHHINSNHVSS(ph)NSTGS(ph)S ddPTM_PC-9_Lapatinib_30min_R1 1 TSFNHHINSNHVSSNSTGSS 20 0 P34947 P34947 GRK5 G protein-coupled receptor kinase 5 4 T(0.984)S(0.985)FNHHINS(0.05)NHVS(0.308)S(0.579)NS(0.205)T(0.193)GS(0.381)S(0.314) 49.093999999999994 0.021308 1071600.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 T(ph)S(ph)LVASVMY(ph)T(ph)MVTPMLNPFIYSLRNTDMK ddPTM_PC-9_Lapatinib_30min_R1 1 TSLVASVMYTMVTPMLNPFIYSLRNTDMK 29 1 O76099 O76099 OR7C1 Olfactory receptor 7C1 4 T(0.632)S(0.632)LVAS(0.743)VMY(0.892)T(0.901)MVT(0.184)PMLNPFIY(0.005)S(0.005)LRNT(0.005)DMK 43.658 0.0097211 11724000.0 22995.0 26116.0 29130.0 20868.0 24902.0 26667.0 22582.0 21292.0 24315.0 15031.0 True False 22667.087083233444 26055.53000656227 26735.04384505178 22402.702333607285 23437.31331921568 25526.514573813183 23751.18546542539 22281.30405026751 21576.388651698875 17629.088322451462 1.2857776119009998 1.4779851079071027 1.5165301435924772 1.2707805374754635 1.3294682566974931 1.4479770086184198 1.347272475524282 1.2638942889571456 1.2239083642357356 1.0 14.105670248042664 -8.583588412062701 0.7383726578686616 0.9980902788666228 1.3979648731108556 0.7063845347708609 0.0764463943298499 0.44226468075405856 0.5378643741572305 0.07825631059440168 0.029705644160849396 2.608624614814494e-09 8.583588412062701 0.3998745942442328 T(ph)S(ph)PFLT(ph)HQVFNS(ph)YHSETNIVRY(ph)MKK ddPTM_PC-9_AZD4547_30min_R2 1 TSPFLTHQVFNSYHSETNIVRYMKK 25 2 P23378 P23378 GLDC Glycine dehydrogenase (decarboxylating), mitochondrial 5 T(0.98)S(0.98)PFLT(0.964)HQVFNS(0.374)Y(0.326)HS(0.374)ET(0.099)NIVRY(0.902)MKK 49.559 0.010144 3974200.0 0.0 0.0 9490.7 8104.9 8523.2 8542.7 3482.2 13515.0 6727.7 7170.6 True False 0.0 0.0 9364.847116886782 6236.440524456748 7339.900801141142 8008.523618544549 3792.109054084747 11426.567293804063 7083.312487128231 6919.559476560772 0.0 0.0 1.3533877624159667 0.9012771037783528 1.060746833090203 1.1573747787951705 0.5480275250079271 1.6513431718464553 1.0236652363668748 1.0 12.756464478418433 -5.252567506642542 24.61814938647431 1.0859370239516908 2.3200790271881965e-07 0.720962204265388 0.2704923103499142 253.96392283024488 704707.8041654824 0.06674893597168059 0.17086182268691508 5.590266258360904e-06 5.252567506642542 -1.0859367919437881 T(ph)S(ph)PLT(ph)SPT(ph)NCSHGGLSPSR ddPTM_PC-9_Lapatinib_30min_R1 1 TSPLTSPTNCSHGGLSPSR 19 0 Q7Z460 Q7Z460 CLASP1 CLIP-associating protein 1 4 T(0.928)S(0.928)PLT(0.583)S(0.583)PT(0.974)NCSHGGLS(0.001)PS(0.001)R 59.155 0.013363 21462000.0 35598.0 34339.0 29536.0 30943.0 34801.0 32188.0 27498.0 26162.0 35954.0 25146.0 True False 35090.365992126324 34259.490155281856 27107.664092257088 33218.65144282206 32754.07360139848 30811.39427389278 28921.71189125265 27377.58202907659 31904.48190759538 29492.452595061164 1.1898083375406558 1.1616358471665047 0.9191390239547783 1.126344149770199 1.110591718197201 1.0447213291122655 0.9806479063764235 0.928291126037489 1.081784629635656 1.0 14.848058181589769 -7.008466251243451 3.548397619299737 0.9925686811018406 1.095713904173864 0.2901303099766017 0.07611319902924624 0.3299166642350359 8.877581935168564 0.030668270947931994 0.024907907247516875 9.806945205277881e-08 7.008466251243451 0.10314522307202334 T(ph)S(ph)RT(ph)KRR ddPTM_PC-9_AZD4547_30min_R2 1 TSRTKRR 7 3 J3KN16 J3KN16 KIAA0368 3 T(1)S(1)RT(1)KRR 68.37100000000001 0.02114 0.0 8493.9 6905.5 11506.0 12906.0 11049.0 9912.8 8304.7 10955.0 7444.7 9931.0 True False 11194.78351590464 9137.567830587437 11353.422922113152 9930.721095712322 9515.037069622731 9292.951048955054 9043.802211664346 9262.156470856347 7838.211643343726 9583.318712761142 1.1681531055622385 0.9534867935071237 1.1847068079865632 1.0362507387434146 0.9928749481067047 0.9697007192905487 0.9437025400837002 0.9664873671083134 0.817901593203445 1.0 13.226309633872114 -6.489627365527134 1.247360018794127 0.9284074985604085 1.0903302569969038 0.47570514034593736 0.07390610270492431 0.3990499102157063 1.2917362493064604 0.03105009055382645 0.036081940912763906 3.238714267441266e-07 6.489627365527134 0.16192275843649528 T(ph)S(ph)RT(ph)KRR ddPTM_PC-9_Lapatinib_30min_R1 2 TSRTKRR 7 3 J3KN16 J3KN16 KIAA0368 3 T(1)S(1)RT(1)KRR;T(1)S(1)RT(1)KRR 68.893 0.020665 0.0 52944.0 40633.0 45475.0 38165.0 42168.0 37939.0 34294.0 32492.0 42055.0 30655.0 True False 52189.00885125949 40538.9167849841 41736.221038576354 40971.7814147078 39687.76114547774 36316.43741012856 36069.575518169266 34001.69693787772 37318.3230412172 35953.67590478008 1.4515625325620989 1.1275319077901131 1.16083321074348 1.1395714174878169 1.1038582327600392 1.0100896916996531 1.0032235817471387 0.9457085007921863 1.037955705559878 1.0 15.133851658934123 -1.522878745280369 0.42537097967237786 0.993711948077595 8.76628593429964 0.842450971622982 0.05394405108161373 31.010502530175284 0.393314662508334 0.03706060019167453 205.8914188074393 0.029999999999997834 1.522878745280369 7.772573986222045 T(ph)SAGSSSGTNSSGQR ddPTM_PC-9_AZD4547_30min_R2 1 TSAGSSSGTNSSGQR 15 0 Q9UHB7;Q9UHB7-2;Q9UHB7-3 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 T(0.977)S(0.023)AGSSSGTNSSGQR 113.43 0.00052543 388040.0 0.0 0.0 686.53 1000.4 657.81 653.12 429.65 948.11 654.55 2125.9 True False 0.0 0.0 677.4261636292665 769.7732360259258 566.484436127118 612.280303152846 467.8880176576621 801.601384900375 689.1481767096908 2051.4728880735993 0.0 0.0 0.3302145339417047 0.3752295438565451 0.27613547291822393 0.29845888128104753 0.22807419019659791 0.39074432304738144 0.335928483732887 1.0 11.002444372599467 -14.522878745274935 0.14651386552324563 3.6214480195514076 0.01180627620286678 0.8338235996541257 0.10679510556576864 58.588806488175464 0.5136289078950799 44.74002245500513 0.6424639933023042 3.000000000037316e-15 14.522878745274935 -3.609641743348541 T(ph)SAGSSSGTNSSGQR ddPTM_PC-9_Lapatinib_30min_R1 1 TSAGSSSGTNSSGQR 15 0 Q9UHB7;Q9UHB7-2;Q9UHB7-3 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 T(0.983)S(0.017)AGSSSGTNSSGQR 140.49 0.00017465 480070.0 475.78 3169.9 2673.0 852.26 2548.3 1089.9 2138.7 1051.5 2488.2 1000.9 True False 468.9952899526338 3162.5602913080756 2453.236258078387 914.938043456017 2398.414004150564 1043.287517680992 2249.4314212605304 1100.356528689475 2207.952714092419 1173.904231384583 0.3995175052733805 2.694053063918115 2.089809536834936 0.7793975172718105 2.0431087477397627 0.8887330753126832 1.9161967059334961 0.9373477829546957 1.880862727181934 1.0 10.197099000995728 -5.727250949156604 24.985872186029614 1.3800957178536846 1.8244191263463299 0.052759069568949046 0.6911999725695325 487.438541146581 356230.395112616 0.17574320557481685 0.30437646986627653 1.873911389600305e-06 5.727250949156604 0.4443234084926453 T(ph)SALSPNAK ddPTM_PC-9_AZD4547_30min_R2 1 TSALSPNAK 9 0 P50616 P50616 TOB1 Protein Tob1 1 T(0.788)S(0.002)ALS(0.21)PNAK 80.706 0.044739999999999995 7778100.0 53061.0 45262.0 54019.0 71529.0 67164.0 57777.0 50052.0 72559.0 52152.0 73305.0 True False 69933.29426263749 59892.05635334858 53302.67276461242 55039.09416203361 57839.43793502958 54164.195056439785 54506.531036427994 61346.6737899467 54908.64824958181 70738.61426230561 0.9886155530742811 0.8466670852677868 0.7535159307328381 0.7780629396830328 0.8176501411316224 0.7656948842055871 0.770534334109409 0.8672303582660994 0.7762188844408974 1.0 16.11021033711696 -10.637644438720343 5.299050219143729 1.000003780216703 0.8144684119449845 0.3969691712038874 0.06706010560816315 3.0498924618811276e-06 5.094837770448743e-07 0.06612243919847312 0.016036720244226647 2.303326802596925e-11 10.637644438720343 -0.18553536827171846 T(ph)SCSPQKAQEANK ddPTM_PC-9_AZD4547_30min_R2 1 TSCSPQKAQEANK 13 1 Q8IY33-4;Q8IY33-2;Q8IY33;Q8IY33-5 Q8IY33-4 MICALL2 MICAL-like protein 2 1 T(0.907)S(0.05)CS(0.043)PQKAQEANK 77.191 0.011818 6112800.0 25697.0 12049.0 26690.0 62861.0 51641.0 32905.0 25060.0 26976.0 19991.0 32880.0 True False 33868.111469195705 15943.603618962867 26336.0731610638 48369.36764276863 44471.538538545356 30847.445148279618 27290.2914523473 22807.47904681157 21047.68344756462 31728.8812078931 1.0674221775197807 0.5024949828674269 0.8300347241525885 1.5244586572669925 1.401610672849136 0.9722197560689846 0.8601088476311726 0.7188239288165579 0.6633604037172496 1.0 14.95350903083081 -7.296045575124625 3.1786078780417237 0.7753758954919975 1.0554688546173532 0.15485198999908367 0.2771575911219596 0.5390575158270076 11.10602561732434 0.1413028509707705 0.09440424557659712 5.057715832433948e-08 7.296045575124625 0.2800929591253557 T(ph)SDANETEDHLESLICK ddPTM_PC-9_AZD4547_30min_R2 4 TSDANETEDHLESLICK 17 0 F2Z2T1;Q09161 F2Z2T1 NCBP1 Nuclear cap-binding protein subunit 1 1 T(0.5)S(0.5)DANETEDHLESLICK;T(0.802)S(0.198)DANETEDHLESLICK;T(0.5)S(0.5)DANETEDHLESLICK;T(0.5)S(0.5)DANETEDHLESLICK 133.93 5.3515e-05 61052100.0 124638.5 116202.8 172850.0 262568.0 186786.0 191255.0 165561.0 200347.0 167968.0 185245.5 True False 164270.95035814878 153763.08263039406 170557.8960618165 202037.00423516115 160853.9880610506 179295.7946158398 180295.60826584478 169387.9746660575 176846.4455665316 178760.1114293423 0.9189463412427968 0.8601643923855535 0.9541160759973689 1.1302130135168291 0.8998315495268117 1.0029966595020234 1.0085897061946587 0.9475714314096896 0.9892947825579806 1.0 17.447665323580367 -5.516303091368919 24.971777432499138 0.9953388364755795 0.8939515625527165 0.3650817189510658 0.056261183016612204 293.46568072434803 1114466.8225018703 0.014798637414378922 0.026892307422803644 3.0457686250888107e-06 5.516303091368919 -0.10138727392286306 T(ph)SDANETEDHLESLICK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSDANETEDHLESLICK 17 0 F2Z2T1;Q09161 F2Z2T1 NCBP1 Nuclear cap-binding protein subunit 1 1 T(0.5)S(0.5)DANETEDHLESLICK;T(0.804)S(0.196)DANETEDHLESLICK;T(0.8)S(0.2)DANETEDHLESLICK 118.84 0.00022459 24181400.0 33372.4 45582.2 45710.6 59110.6 72148.0 71034.0 106108.0 91799.0 77745.0 59125.0 True False 39021.68818505502 50107.29957373482 46800.514062415845 55798.82472115084 58011.11731875155 67308.8519917897 96056.68208460564 89389.37351908059 78881.87354591025 69843.89446675757 0.5586986304669411 0.7174184652258122 0.6700730882738891 0.7989076947550294 0.8305825120671375 0.9637041649191767 1.3753053551491767 1.2798452062495707 1.129402564793324 1.0 16.09184638484028 -6.802439832875366 1.7430999146140704 1.2178798724225346 0.6882998397672886 0.8008658230730231 0.11325429574598304 0.14695750844546657 0.9226113016293798 0.04864079781086104 0.04303458779725152 1.576014348528652e-07 6.802439832875366 -0.529580032655246 T(ph)SDANETEDHLESLICK ddPTM_PC-9_Lapatinib_30min_R1 3 TSDANETEDHLESLICK 17 0 F2Z2T1;Q09161 F2Z2T1 NCBP1 Nuclear cap-binding protein subunit 1 1 T(0.773)S(0.226)DANET(0.001)EDHLESLICK;T(0.5)S(0.5)DANETEDHLESLICK;T(0.847)S(0.153)DANETEDHLESLICK 169.51 3.3941e-05 16392300.0 31566.5 53540.0 78748.4 63054.0 103766.0 117432.0 110171.0 120785.0 147741.0 94453.0 True False 31116.355921412855 53416.03141948781 72274.01052961474 67691.20150197785 97662.68789180528 112409.70710736237 115875.115309157 126397.11204732093 131100.852798299 110779.07519928859 0.28088658318762244 0.4821852080223074 0.6524157238142287 0.6110468189069388 0.881598692858852 1.0147196743170162 1.0460018293229183 1.1409836363043824 1.1834441889179168 1.0 16.75732587426147 -5.926587560291012 0.6308219229811932 1.139675064995757 0.2532968234491803 0.9369442932284855 0.07260250010526532 0.2565576188815947 0.18589159963069168 0.045383828889989576 0.1377177524934182 1.184165597356633e-06 5.926587560291012 -0.8863782415465766 down T(ph)SDIFGSPVTATSR ddPTM_PC-9_AZD4547_30min_R2 1 TSDIFGSPVTATSR 14 0 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2;H3BMV3;H3BMT0;H3BTV5 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 T(0.952)S(0.031)DIFGS(0.015)PVT(0.003)ATSR 177.42 0.00021566 331330000.0 82068.0 78130.0 106060.0 147020.0 116180.0 108210.0 88085.0 128810.0 94525.0 117020.0 True False 108163.9168795562 103383.99458457707 104653.575101627 113126.81043635712 100050.41241277673 101443.6115938411 95924.39435674428 108905.37425933396 99521.39852338779 112923.16541811592 0.9578540991041311 0.9155251201273135 0.9267679905547328 1.0018033945248273 0.8860043202147603 0.8983419054737798 0.8494660418132011 0.9644201334251882 0.8813195959827554 1.0 16.784981949968397 T(ph)SDIFGSPVTATSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSDIFGSPVTATSR 14 0 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2;H3BMV3;H3BMT0;H3BTV5 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 T(0.758)S(0.072)DIFGS(0.17)PVTATSR 161.87 0.0012873 171570000.0 73605.0 86299.0 85051.0 86705.0 98660.0 108950.0 100850.0 102380.0 88427.0 71196.0 True False 86064.87273498376 94866.19438977828 87078.9383977136 81847.19995140254 79328.28123673599 103236.47020448647 91296.7579092288 99692.6334805765 89720.07758755183 84103.2712127739 1.0233237244392928 1.1279727057200322 1.035381111127194 0.9731749879780097 0.9432246819037797 1.2274964899201988 1.0855315922047313 1.1853597611960047 1.0667846362428388 1.0 16.359874295019942 -6.753121527676115 24.999857177242305 1.1229005547781525 1.0247644865240715 0.27578923215969053 0.07387044548511179 240.60983512496765 723168.6092550138 0.024594850075723387 0.02420286593027325 1.7655437033179874e-07 6.753121527676115 -0.09813606825408105 T(ph)SDSDQQAYLVQR ddPTM_PC-9_AZD4547_30min_R2 3 TSDSDQQAYLVQR 13 0 Q96CV9-3;Q96CV9-2;Q96CV9 Q96CV9-3 OPTN Optineurin 1 T(0.999)S(0.001)DSDQQAYLVQR;T(0.998)S(0.002)DSDQQAYLVQR;T(0.988)S(0.012)DSDQQAYLVQR 247.17 8.9152e-34 28938300.0 42086.3 47030.0 53470.0 77261.0 68156.0 66277.0 48666.0 57740.0 48204.0 52035.0 True False 55468.86795057836 62231.52777822419 52760.952863322666 59449.670120550894 58693.71585819598 62132.68871273445 52997.17972146577 48817.60973320358 50751.96502958359 50213.27048822136 1.1046655079674568 1.2393442445224112 1.0507372324154611 1.1839433986777685 1.1688885286204151 1.237375859182665 1.0554417030832006 0.9722053405116251 1.0107281309527247 1.0 15.615781073156667 -7.475192946883738 5.134803801890827 0.9962298852840057 1.1631833537565597 0.6761364446907601 0.05361590320279856 0.11568064831987536 7.045522754708469 0.02302652705173574 0.014763965008541404 3.348166548984239e-08 7.475192946883738 0.166953468472554 T(ph)SDSDQQAYLVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSDSDQQAYLVQR 13 0 Q96CV9-3;Q96CV9-2;Q96CV9 Q96CV9-3 OPTN Optineurin 1 T(0.986)S(0.014)DSDQQAYLVQR;T(0.999)S(0.001)DSDQQAYLVQR 202.92 2.944e-08 13483300.0 21560.2 22562.0 22828.0 28215.0 35290.0 40497.0 41854.0 42003.0 39646.0 33856.0 True False 25209.916026639476 24801.806252936567 23372.30609567211 26634.2050242642 28375.177831384684 38373.26602910594 37889.28612328079 40900.46575585721 40225.74774713689 39993.82479605147 0.6303452134222585 0.6201408937358052 0.5843978717929379 0.6659579362585435 0.7094889767628857 0.9594797753100741 0.9473784094543901 1.0226695237184529 1.0057989690225457 1.0 15.287489638952824 -6.693225658708067 1.8738162101420224 1.0001179129536422 0.6175913253270998 0.9763404440629515 0.027114663430273574 0.045545577376883736 0.32942180105306307 0.010747761664185543 0.010337274793842758 2.0266294125425384e-07 6.693225658708067 -0.38252658762654235 T(ph)SDSDQQAYLVQR ddPTM_PC-9_Lapatinib_30min_R1 3 TSDSDQQAYLVQR 13 0 Q96CV9-3;Q96CV9-2;Q96CV9 Q96CV9-3 OPTN Optineurin 1 T(0.604)S(0.393)DS(0.003)DQQAYLVQR;T(0.939)S(0.055)DS(0.006)DQQAYLVQR;T(0.998)S(0.002)DSDQQAYLVQR 191.63 2.4160999999999998e-05 27169800.0 38394.2 40053.0 42997.0 37040.0 54896.0 58550.0 65165.0 62742.0 73767.0 62989.0 True False 37846.69166736605 39960.259739348985 39461.952633219735 39764.04516181783 51667.12520968857 56045.952986716235 68538.92484520607 65657.22237093204 65458.58365905288 73876.5647224334 0.5122963122278682 0.540905764764325 0.5341606337745249 0.538249786129309 0.6993709764904554 0.7586431935119107 0.9277492138774762 0.8887422231612583 0.8860534312199236 1.0 16.17282916177212 -6.744792568861823 1.1162707588789278 0.9310153533368674 0.518805231732845 0.9604392085187262 0.0356672285209539 0.08458656923376504 0.22412149139391688 0.018299297645765725 0.01679958418811177 1.7997303111896805e-07 6.744792568861823 -0.4122101216040224 T(ph)SDSTPDPQRVPLR ddPTM_PC-9_AZD4547_30min_R2 1 TSDSTPDPQRVPLR 14 1 P52948-6;P52948-2;P52948-5;P52948;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 T(0.334)S(0.334)DS(0.053)T(0.28)PDPQRVPLR 63.894 0.030836000000000002 10932000.0 27899.0 23906.0 36959.0 54491.0 38272.0 30478.0 36151.0 36248.0 27090.0 32850.0 True False 36770.30166475043 31633.14699269037 36468.8995114184 41928.94182755771 32958.59342280759 28572.205841947012 39368.36896623333 30646.704496175338 28521.922094668895 31699.93149876183 1.1599489313150926 0.9978932286943879 1.1504409564053109 1.3226824111337723 1.0397055092719971 0.9013333622838591 1.2419070674575754 0.9667751016235593 0.8997471207716311 1.0 14.95219210235882 -6.499753470519208 24.639280955891838 1.0099449299419678 1.150226179438147 0.29022322853535787 0.11521721073308176 952.6487778884681 1015019.5575196008 0.03709706954581216 0.04176745135831817 3.164073252823822e-07 6.499753470519208 0.14028124949617915 T(ph)SDTETEPSK ddPTM_PC-9_AZD4547_30min_R2 1 TSDTETEPSK 10 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 T(0.976)S(0.024)DTETEPSK 129.0 0.00063784 5097500.0 30240.0 63333.0 36436.0 37080.0 40903.0 40359.0 33585.0 34641.0 29727.0 32758.0 True False 39855.69096892551 83804.15370568307 35952.83483314054 28531.778880289214 35224.32448717338 37835.3453499291 36573.99993723398 29288.02942098902 31298.308531126688 31611.152390759187 1.2608110731381128 2.651094546308958 1.1373465411419341 0.902585850955242 1.1143005497474499 1.1968986414107894 1.15699672967081 0.9265093869070942 0.990103370615367 1.0 14.948146009481162 -5.406837582766596 8.531490913934789 1.0500350128522757 1.953014044466161 0.5560115538608386 0.3235949538125009 0.19081983361753252 12.872546869514325 0.07735306878303758 0.16144938804334855 3.918884079373567e-06 5.406837582766596 0.9029790316138853 T(ph)SDTETEPSK ddPTM_PC-9_Lapatinib_30min_R1 1 TSDTETEPSK 10 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 T(0.994)S(0.006)DTETEPSK 167.11 0.0026015 4236800.0 16347.0 43174.0 27299.0 16383.0 19650.0 27292.0 50556.0 42056.0 20303.0 11922.0 True False 16113.888782327353 43074.03325560263 25054.58159718737 17587.86047208588 18494.22563338641 26124.784780759353 53173.5423075922 44010.075292976275 18016.26233993182 13982.701814933549 1.1524159633524969 3.0805229079260985 1.7918269250674455 1.2578299033239781 1.3226503631533175 1.8683645783576703 3.802808857069581 3.1474657670217527 1.288467892570692 1.0 13.771355532708819 -7.031154151391892 24.9920762691679 2.5382048026729143 1.7568463380876482 0.06279240222132054 0.919486901714853 1399.4124565914665 1122614.2834146977 0.35183143993073335 0.272849378729842 9.307774404497286e-08 7.031154151391892 -0.781358464585266 T(ph)SDVGGYYYEK ddPTM_PC-9_AZD4547_30min_R2 3 TSDVGGYYYEK 11 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.99)S(0.01)DVGGYYYEK;T(1)SDVGGYYYEK;T(0.623)S(0.377)DVGGYYYEK 213.06 3.8725e-08 64811000.0 130983.0 142151.0 176483.0 228053.0 245621.0 254855.0 240103.0 281754.0 259528.0 243440.0 True False 172632.86938435063 188098.53083568695 174142.72010805632 175478.90423372705 211520.7638770754 238918.8765617623 261471.70185885616 238215.39336281663 273246.12024308724 234917.239697369 0.734866753954474 0.8007012643176123 0.7412939141137315 0.7469818071240191 0.9004054540635928 1.0170342409503381 1.1130375199184863 1.0140396408100847 1.163159079321276 1.0 17.841793065663722 -6.603075331600513 1.9977434284357893 1.0736168586364558 0.7564106874807328 0.9019191771746057 0.04767223882043181 0.08790802240645983 0.7151203442366323 0.017049853066226046 0.017462381775385023 2.4941620585026053e-07 6.603075331600513 -0.317206171155723 T(ph)SDVGGYYYEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSDVGGYYYEK 11 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.989)S(0.011)DVGGYYYEK;T(0.918)S(0.082)DVGGYYYEK;T(0.902)S(0.098)DVGGYYYEK 173.19 0.0010157999999999999 30399300.0 56283.0 78131.0 88762.0 100852.0 116351.0 97621.0 114134.0 86930.0 84466.0 75041.0 True False 65810.60026007869 85887.32933020956 90878.42271175954 95201.58940659562 93552.85678264186 92501.58290805109 103322.40126139739 84648.17960994838 85701.15545602732 88645.33927577084 0.7424033885791275 0.9688871409586323 1.0251912108886143 1.0739604606896325 1.0553612580984546 1.0435019332520539 1.165570599712716 0.9549084058058878 0.9667869304376588 1.0 16.435757159793617 -4.679562493772403 1.9859468525610267 1.0415054118130744 0.5951850537235932 0.7090577762193084 0.05629720425478883 0.5840160559664095 1.9998206873550346 0.015717878410384672 0.5246703128584643 2.0914019385059638e-05 4.679562493772403 -0.44632035808948123 T(ph)SDVGGYYYEK ddPTM_PC-9_Lapatinib_30min_R1 3 TSDVGGYYYEK 11 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.592)S(0.408)DVGGYYYEK;T(0.989)S(0.011)DVGGYYYEK;T(0.999)S(0.001)DVGGYYYEK 221.09 6.9157e-09 77723000.0 298466.0 307878.0 352197.0 317501.0 335354.0 295208.0 289204.0 259138.0 299090.0 262734.0 True False 294209.82010803843 307165.12740696745 323240.72217973496 340851.08269228664 315629.1370513313 282582.64200345933 304177.5680339598 271178.49750977923 265403.33464267367 308147.2218289506 0.9547703151818493 0.9968129051556781 1.048981458476892 1.1061306367431396 1.0242803267151757 0.9170377728095114 0.9871176713149328 0.8800290195713906 0.8612874491206556 1.0 18.23326025865817 -6.747577770510004 9.00350595763325 0.9251793696292231 1.030397985906376 0.45021158700366415 0.053465407762263537 0.1712500557370247 90.46015176348902 0.018986552123568517 0.0184000987417668 1.788225277181233e-07 6.747577770510004 0.10521861627715301 T(ph)SETSISPPGSSIGSPNR ddPTM_PC-9_Lapatinib_30min_R1 1 TSETSISPPGSSIGSPNR 18 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 T(0.997)S(0.002)ETSISPPGSSIGSPNR 193.31 5.3525e-14 28920000.0 27014.0 25700.0 31193.0 22592.0 31298.0 28044.0 25862.0 22052.0 28683.0 17975.0 True False 26628.775406239132 25640.493229003285 28628.431948462076 24253.491044702707 29457.113174235517 26844.623493756964 27201.007816262154 23076.616424783926 25452.418494619724 21081.95479981803 1.263107508724427 1.2162293996202194 1.3579590801849732 1.1504384330105883 1.3972666886891236 1.2733460321235806 1.290250741667321 1.094614642897494 1.2073082755513458 1.0 14.363721024952016 -8.437848520298825 0.8531541517535578 1.0091016309418328 1.2797150004219349 0.5271220245070566 0.07809596764104725 0.46046119558615967 0.748345281602067 0.07136863269279452 0.02581531749442768 3.648811934328893e-09 8.437848520298825 0.27061336948010206 T(ph)SFSFQK ddPTM_PC-9_AZD4547_30min_R2 1 TSFSFQK 7 0 H0Y7F8;Q9BPZ7-4;Q9BPZ7-3;Q9BPZ7-2;Q9BPZ7 H0Y7F8 MAPKAP1 Target of rapamycin complex 2 subunit MAPKAP1 1 T(0.978)S(0.015)FS(0.007)FQK 104.01 0.025459 20429000.0 176970.0 158140.0 181580.0 232500.0 224790.0 193540.0 181870.0 250080.0 172190.0 199710.0 True False 233242.77879532898 209255.66240375023 179172.13055773574 178900.71708919224 193581.78865784153 181437.9132046203 198056.07767112515 211435.88226670542 181291.61186714805 192718.2136869934 1.2102788539445173 1.0858115504516683 0.9297104156887902 0.9283020720592445 1.0044810241560806 0.9414673877130566 1.027697765986983 1.0971245437658146 0.9407082413164951 1.0 17.556133400788454 -4.937985196222665 3.2302017844838145 0.9863193651846275 1.21147884854411 0.6616695359675847 0.050735550879791376 0.1707432698813892 3.28892166136119 0.013857560567830005 0.0798113898017283 1.1534925762028245e-05 4.937985196222665 0.22515948335948244 T(ph)SFSFQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSFSFQK 7 0 H0Y7F8;Q9BPZ7-4;Q9BPZ7-3;Q9BPZ7-2;Q9BPZ7 H0Y7F8 MAPKAP1 Target of rapamycin complex 2 subunit MAPKAP1 1 T(0.99)S(0.01)FSFQK;T(0.985)S(0.015)FSFQK 102.07 0.026887 18732400.0 207521.0 220827.0 177008.0 196067.0 249496.0 169159.0 188441.0 180144.0 173023.0 141947.0 True False 242650.20657341985 242749.24516519962 181228.54202657857 185082.00164779037 200609.04982202145 160288.00425259984 170590.50428530498 175415.41087834522 175553.134047643 167680.86744816595 1.447095367922215 1.4476860053234102 1.0807943970268434 1.1037753111875064 1.1963741175422673 0.9559111107422472 1.017352229156606 1.0461265709552117 1.0469479119429683 1.0 17.35535855980703 -5.271702271884629 5.100974667260813 1.0577566092058062 1.4524084981877177 0.8688236721776776 0.06088982703745315 0.05668616663841983 4.772323581958029 0.017056365621211062 0.04081602769183186 5.349309526009346e-06 5.271702271884629 0.3946518889819115 T(ph)SFYLPK ddPTM_PC-9_AZD4547_30min_R2 2 TSFYLPK 7 0 Q9NS23-3;Q9NS23-4;Q9NS23-2;Q9NS23-5;Q9NS23 Q9NS23-3 RASSF1 Ras association domain-containing protein 1 1 T(0.651)S(0.349)FYLPK;T(0.663)S(0.337)FYLPK 112.41 0.022431 16996100.0 133052.0 109231.0 138146.0 174371.0 170236.0 133402.0 138732.0 149391.0 122178.0 142098.0 True False 175359.76834647736 144537.78462137378 136314.0937770072 134172.45995509482 146601.6698872564 125060.3518514146 151078.87924050435 126306.05361366515 128636.0796486693 137123.1922712649 1.278848351193361 1.0540724893236215 0.9940994774052728 0.9784811579478635 1.0691238109250012 0.912029174495975 1.1017748109424954 0.921113719142414 0.9381059288219755 1.0 17.06511307578745 -4.704532810369167 2.2246905553013896 0.9900620303344517 1.3938836049349337 0.6981139978115849 0.057092796497809906 0.4494783808053511 2.1715639464650924 0.01449051492856896 0.3897871944208433 1.974545699478824e-05 4.704532810369167 0.40382157460048196 T(ph)SFYLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSFYLPK 7 0 Q9NS23-3;Q9NS23-4;Q9NS23-2;Q9NS23-5;Q9NS23 Q9NS23-3 RASSF1 Ras association domain-containing protein 1 1 T(0.999)S(0.001)FYLPK 117.04 0.01842 9920400.0 36637.0 49375.0 36383.0 34447.0 39794.0 33631.0 44557.0 42701.0 38354.0 32704.0 True False 42838.92048626588 54276.62369199289 37250.508703295855 32517.046268680813 31996.65136361921 31867.33115600813 40336.238395255445 41580.14399544935 38914.85469136071 38632.97631527844 1.1088692762541332 1.404929903641096 0.9642153480306446 0.8416914607695156 0.828221235208463 0.8248738304795156 1.044088295607279 1.0762863222372376 1.0072963152976333 1.0 15.237545207776419 -5.334373995456319 7.801191839540498 0.9411531517495061 1.255984698999973 0.5649838271900969 0.10820506706113435 0.19922848200657545 19.211677174348303 0.030382220824907703 0.06369070572240566 4.630479912671924e-06 5.334373995456319 0.3148315472504669 T(ph)SFYLPK ddPTM_PC-9_Lapatinib_30min_R1 2 TSFYLPK 7 0 Q9NS23-3;Q9NS23-4;Q9NS23-2;Q9NS23-5;Q9NS23 Q9NS23-3 RASSF1 Ras association domain-containing protein 1 1 T(0.929)S(0.071)FYLPK;T(0.647)S(0.353)FYLPK 111.74 0.022674 12063700.0 94025.0 119221.0 123125.0 119446.0 129467.0 110444.0 114863.0 127087.0 117261.0 114171.0 True False 92684.18625792686 118944.95109941653 113002.13777624416 128230.45730017555 121852.00560191536 105720.56757753869 120810.04411102453 132991.9259739031 104053.83136692832 133905.30522670542 0.6921621671449831 0.8882766138207848 0.8438958978132225 0.9576204399301268 0.9099863922166229 0.7895173936428495 0.9022050613042535 0.9931789166138268 0.7770702676101017 1.0 17.030853594715445 -4.759809466925245 6.049401112761736 0.893627472239122 0.6847002788679913 0.4150065473371175 0.072499801246243 0.13296812705894345 19.02088468611163 0.017275202825351308 0.11494405900655046 1.738563401591942e-05 4.759809466925245 -0.20892719337113064 T(ph)SGETTQTHTEPTGDSK ddPTM_PC-9_AZD4547_30min_R2 1 TSGETTQTHTEPTGDSK 17 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 T(0.409)S(0.409)GET(0.091)T(0.091)QT(0.001)HTEPTGDSK 101.17 0.0022813000000000004 8569600.0 12093.0 21262.0 19187.0 21061.0 20262.0 18871.0 15056.0 22156.0 18801.0 18819.0 True False 15938.322449974075 28134.525698928428 18932.56784343692 16205.711839206346 17448.971047578583 17690.993386816128 16395.954832663232 18732.299294230317 19794.782476997767 18160.152538057788 0.8776535558593201 1.5492450099175978 1.042533525187104 0.8923775174930074 0.9608383525970501 0.9741654619773454 0.9028533652623584 1.0315056140070131 1.0900119057653468 1.0 14.148488700293656 -5.504623576605404 24.92819741674773 0.9753665385485499 1.2340593033143863 0.2491450352321567 0.15988336329793396 791.8598490508524 1081316.1092396087 0.03887510203696799 0.07856149295814577 3.1287900612885226e-06 5.504623576605404 0.25869276476583636 T(ph)SGETTQTHTEPTGDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSGETTQTHTEPTGDSK 17 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 T(0.713)S(0.196)GET(0.042)T(0.042)QT(0.008)HTEPTGDSK 88.471 0.005704 5986900.0 15051.0 22722.0 21157.0 21034.0 22300.0 15608.0 22407.0 18566.0 17263.0 10932.0 True False 17598.83702919966 24977.689995533412 21661.46311836931 19855.53317314809 17930.475081889446 14789.489003686333 20284.446747368296 18078.66217230305 17515.43871661262 12913.88506233562 1.362784084282125 1.9341731690320558 1.677377722800608 1.537533676140447 1.3884648187078197 1.145239324362663 1.5707470408366504 1.399939838788787 1.3563260499892322 1.0 13.656635471362005 -8.331225360426924 0.061965278712973186 4.753216982189818e-13 2.6447023496256317 0.4648306638120444 0.18285831233692315 28.079570851867267 1.4120773591929718 30.85641113832431 27.68404290692792 4.664172881850891e-09 8.331225360426924 2.6447023496251565 T(ph)SGETTQTHTEPTGDSK ddPTM_PC-9_Lapatinib_30min_R1 1 TSGETTQTHTEPTGDSK 17 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 T(0.781)S(0.21)GET(0.004)T(0.004)QT(0.001)HTEPTGDSK 70.072 0.03191 6469400.0 10636.0 16820.0 13017.0 8934.5 11992.0 12193.0 16272.0 11876.0 10651.0 6862.8 True False 10484.328689596481 16781.054323417728 11946.792507073083 9591.57293461828 11286.654137179123 11671.53381327124 17114.484540492518 12427.802315469527 9451.37221999772 8049.025835893807 1.3025587075199447 2.084855318588286 1.484253219041438 1.1916439492398747 1.402238527654793 1.4500554540678985 2.126280234332486 1.5440132220782563 1.1742256035320813 1.0 12.974598470775074 -8.352443355415284 3.443767511376933 1.019833533031277 1.5843311373907765 0.3172497128674373 0.290138669822651 0.29450534740097456 6.233447796030714 0.2863958070265253 0.07721138527754577 4.441775912161883e-09 8.352443355415284 0.5644976043594994 T(ph)SIETNIR ddPTM_PC-9_Lapatinib_30min_R1 1 TSIETNIR 8 0 A0A0C4DG88;P14859-4;P14859-5;P14859-3;P14859;P14859-2;P14859-6;A0A0A0MT46;H0YLC5;Q9UKI9-3;Q9UKI9;Q9UKI9-2 A0A0C4DG88 POU2F1;POU2F3 POU domain protein;POU domain, class 2, transcription factor 1;POU domain, class 2, transcription factor 3 1 T(0.977)S(0.023)IETNIR 92.611 0.019181 1869800.0 18005.0 23970.0 27169.0 16767.0 22440.0 20105.0 23163.0 23200.0 26941.0 21710.0 True False 17748.24539828739 23914.498937712397 24935.269695372866 18000.10111307234 21120.12331873745 19245.15601704406 24362.266802570553 24277.95669576396 23906.620878692946 25462.544573243358 0.6970334542659049 0.9392030269764285 0.9792921372664158 0.7069246775904428 0.8294584721485759 0.7558221827235336 0.9567883811648188 0.9534772389274798 0.9388936290293071 1.0 14.6360889802405 -7.284027777346918 23.513874548463118 0.9584129674441736 0.8262763811875877 0.40018404252715656 0.08615464087445758 453.05547236234423 471614.4861533086 0.03718536707321132 0.025097364358400133 5.199627388065977e-08 7.284027777346918 -0.13213658625658586 T(ph)SIQSELHR ddPTM_PC-9_AZD4547_30min_R2 1 TSIQSELHR 9 0 A0A0U1RQE4;A0A494C1M0 A0A0U1RQE4 1 T(0.866)S(0.134)IQSELHR 111.52 0.0046747 3825100.0 15376.0 12752.0 19947.0 33157.0 46176.0 27612.0 23941.0 47182.0 36900.0 33908.0 True False 20265.248159331954 16873.83462104859 19682.489746861742 25513.165920543423 39765.25945577872 25885.41727501282 26071.702620137523 39891.10603449967 38850.45866715696 32720.891240791952 0.6193366803550877 0.5156899455114043 0.6015267005418329 0.7797209963748506 1.2152865630446157 0.7910975616318912 0.7967907239529856 1.219132625115323 1.187328865257909 1.0 14.997924424013698 -5.974593425920905 3.4486609835801265 1.0222407503687923 0.5746348923932053 0.6593512479457195 0.14751812024250519 0.15698743166439566 3.945209122694139 0.04719975367028114 0.07022338553805815 1.0602458325535018e-06 5.974593425920905 -0.44760585797558694 T(ph)SIQSELHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSIQSELHR 9 0 A0A0U1RQE4;A0A494C1M0 A0A0U1RQE4 1 T(0.971)S(0.029)IQSELHR 114.71 0.0018419 0.0 31746.0 40688.0 42492.0 41886.0 57276.0 29267.0 19979.0 34569.0 20001.0 14715.0 True False 37119.970787919265 44727.235742375844 43505.17043180739 39539.26321624422 46053.178959206234 27732.18699839105 18086.444484566033 33661.60037888313 20293.476786825515 17382.71301612409 2.1354532375634934 2.57308716429289 2.5027836789028433 2.2746313063770804 2.649366581412672 1.5953888770220654 1.0404845588711709 1.9364986551672834 1.1674516381879756 1.0 14.085365648666555 -6.8664766881310175 4.94519167587967 1.3597760079893153 2.428671826886449 0.7873703784485169 0.28243932631813845 0.09551574116830319 3.78590981632253 0.09649376353316315 0.08524939530482085 1.359951160188084e-07 6.8664766881310175 1.0688958188971338 up T(ph)SIQSELHR ddPTM_PC-9_Lapatinib_30min_R1 1 TSIQSELHR 9 0 A0A0U1RQE4;A0A494C1M0 A0A0U1RQE4 1 T(0.552)S(0.447)IQS(0.001)ELHR 94.538 0.011984999999999999 3489200.0 18778.0 17898.0 20876.0 30093.0 16588.0 10512.0 10135.0 14815.0 21831.0 25319.0 True False 18510.222276536544 17856.55828064985 19159.65586369039 32306.139607305176 15612.326453262785 10062.426264668853 10659.740709064143 15503.358984816527 19372.162889378487 29695.35541455314 0.6233372868628819 0.6013249557504431 0.6452071576924315 1.0879189407334906 0.5257497758592737 0.33885522244793354 0.35896996551319277 0.5220802636771479 0.6523633955189015 1.0 14.857949679451371 -8.573038635510946 14.71298606666104 1.0000000088161356 0.5888368725206995 0.28610853236674705 0.19426085509253777 113.88266086858044 33406.01810511927 0.2083661903186785 0.053800949357168004 2.672768624442841e-09 8.573038635510946 -0.4111631362954361 T(ph)SIVQAAAGGVPGGGSNNGK ddPTM_PC-9_AZD4547_30min_R2 1 TSIVQAAAGGVPGGGSNNGK 20 0 Q9NR12-2;Q9NR12 Q9NR12-2 PDLIM7 PDZ and LIM domain protein 7 1 T(0.817)S(0.183)IVQAAAGGVPGGGSNNGK 128.66 2.2279e-06 0.0 18950.0 23057.0 27399.0 33161.0 34644.0 34743.0 30144.0 41405.0 31316.0 32725.0 True False 24975.705815513822 30509.724345790255 27035.67135781144 25516.243782342786 29834.278598969133 32570.514717723094 32826.75760333428 35006.80864224617 32971.299827118884 31579.307710714795 0.7908883261250093 0.9661302465930363 0.856119823951628 0.8080051664237458 0.9447413753420068 1.031387863726727 1.0395021291805022 1.1085362910083185 1.0440792473715879 1.0 14.946691923981732 -6.631991265452135 2.698260367177667 1.053952215519971 0.863405631516006 0.7535198550032348 0.050848710256760354 0.13431111683674254 1.9823852200814134 0.01815983698114937 0.01815792018059125 2.3335049933541458e-07 6.631991265452135 -0.19054658400396496 T(ph)SIVQAAAGGVPGGGSNNGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSIVQAAAGGVPGGGSNNGK 20 0 Q9NR12-2;Q9NR12 Q9NR12-2 PDLIM7 PDZ and LIM domain protein 7 1 T(0.602)S(0.398)IVQAAAGGVPGGGSNNGK 191.89 4.8181e-48 0.0 18851.0 20542.0 15796.0 17441.0 22675.0 15210.0 14532.0 20488.0 15784.0 11995.0 True False 22042.10197577855 22581.2740026515 16172.636546663585 16463.83731448491 18231.996523849473 14412.360824325287 13155.42375743099 19950.211708830375 16014.811139605721 14169.59854763224 1.5555911412509154 1.5936424681858654 1.1413616618916882 1.161912757029806 1.2866981702100562 1.0171326150050746 0.9284260039695535 1.4079588523108924 1.1302233500667398 1.0 13.790511264019594 -5.2628164619070965 24.451754242472898 1.1436881517721589 1.57461684972832 0.6394990737879527 0.13211133868771138 53.120423467449186 943249.208529578 0.034856070146355674 0.07954659493322115 5.459885536976381e-06 5.2628164619070965 0.43092869795616107 T(ph)SLAGDTSNSSSPASTGAK ddPTM_PC-9_AZD4547_30min_R2 1 TSLAGDTSNSSSPASTGAK 19 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y6T5;H0Y4F5;H0Y314 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 T(0.821)S(0.179)LAGDTSNSSSPASTGAK 139.12 0.00036639999999999996 5890200.0 38167.0 43930.0 50195.0 59334.0 60022.0 61051.0 54518.0 58199.0 56637.0 60429.0 True False 50303.31207708266 58129.51340202826 49529.38150316964 45655.46300116182 51688.98135513583 57233.47131887611 59369.99638463964 49205.681829974266 59630.71619327285 58313.39910315606 0.8626372814950539 0.9968465960833031 0.8493653648203985 0.7829326313219639 0.8863997323102076 0.9814806236492994 1.0181192881521872 0.8438143306125871 1.0225902984627335 1.0 15.831539799829637 -6.714747101271611 6.595650566121552 0.9662186434215574 0.8751388504807976 0.3369078492916142 0.06815035685137798 0.2708421950416598 27.93806481907406 0.02354537643601357 0.02326382123265272 1.9286476779943579e-07 6.714747101271611 -0.09107979294075974 T(ph)SLAGDTSNSSSPASTGAK ddPTM_PC-9_Lapatinib_30min_R1 1 TSLAGDTSNSSSPASTGAK 19 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y6T5;H0Y4F5;H0Y314 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 T(0.983)S(0.017)LAGDTSNSSSPASTGAK 277.64 1.3617999999999997e-91 5847900.0 35422.0 34899.0 29270.0 29570.0 29471.0 26317.0 24990.0 26498.0 32073.0 22178.0 True False 34916.875784400756 34818.19350968817 26863.5335854674 31744.67644262831 27737.573722215322 25191.48325792335 26283.85992299091 27729.193815704915 28460.600996337158 26011.437749672554 1.3423662359778752 1.3385724328185773 1.0327585058540478 1.220412218199201 1.0663606521544353 0.9684771561018566 1.0104731686091355 1.066038489781442 1.0941571654068 1.0 14.666858524197375 -4.954215537052623 0.7795085185012168 1.0343911671214083 1.523261268250553 0.7069961414380472 0.07065174649224004 1.1843471374607462 0.6510159536178626 0.02868881230105287 0.48267955976170457 1.1111801201601916e-05 4.954215537052623 0.48887010112914475 T(ph)SLDLRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSLDLRR 7 1 Q5T457;A0A0A0MRN9;Q9GZV1-2;Q9GZV1 Q5T457 ANKRD2 Ankyrin repeat domain-containing protein 2 1 T(0.99)S(0.01)LDLRR 70.256 0.037737 2006500.0 24514.0 17779.0 24710.0 31479.0 31546.0 27976.0 25036.0 35026.0 25473.0 19884.0 True False 28663.736026430168 19543.98162268236 25299.18011319684 29715.33368629497 25364.78775485581 26508.889311066672 22664.408835056587 34106.60461311463 25845.494434818593 23488.811798342605 1.2203144319310657 0.8320549285537467 1.0770736438435755 1.2650845833075182 1.0798667881806425 1.128575150529205 0.9649023130516892 1.4520361824143537 1.100332135005751 1.0 14.519686114781406 -5.5242554876460845 24.97343516656316 1.1515357821598586 1.0082795777952362 0.07788337484987506 0.15661683211419694 84.79619542563871 1538158.1625948907 0.04084601070265702 0.07143317238000617 2.99050485872125e-06 5.5242554876460845 -0.14325620436462239 T(ph)SLDVSNSAEPGFLAPGAR ddPTM_PC-9_AZD4547_30min_R2 1 TSLDVSNSAEPGFLAPGAR 19 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 T(0.994)S(0.006)LDVSNSAEPGFLAPGAR 98.368 0.0020213 0.0 5226.1 4323.3 7514.2 10663.0 8549.2 7314.9 6953.8 8541.1 6412.7 9294.0 True False 6887.891090367116 5720.722178260614 7414.556798308942 8204.810091707766 7362.291149933809 6857.498146638825 7572.674728704408 7221.269249952636 6751.662230213477 8968.619888873434 0.7679989982530431 0.6378598099979466 0.8267221590590009 0.9148353027968932 0.8208945457781688 0.7646101888147039 0.8443522885944971 0.8051706215034734 0.7528094973218412 1.0 13.13067028177249 -14.522878745280336 0.27078465007995933 2.3889895220318396 0.7808095309469292 0.4442192371409244 0.06885160322022096 221.51425297259954 2.1466267447412086 172.48850024515218 0.09171106398999954 3.0000000000000132e-15 14.522878745280336 -1.6081799910849104 T(ph)SLDVSNSAEPGFLAPGAR ddPTM_PC-9_Lapatinib_30min_R1 1 TSLDVSNSAEPGFLAPGAR 19 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 T(0.991)S(0.009)LDVSNSAEPGFLAPGAR 106.87 0.00159 0.0 6072.4 8742.1 10053.0 6768.3 6457.3 8009.8 7243.9 4564.9 8205.2 5392.7 True False 5985.806462458225 8721.858204563021 9226.48114570221 7266.063360386919 6077.494309540256 7667.239525755765 7618.953697325083 4777.001918986768 7281.043971413513 6324.821009678924 0.9463993452618022 1.378988937586675 1.4587734785826905 1.148817231233517 0.960895857802113 1.2122460879165633 1.204611748801387 0.7552785939201258 1.1511857743122331 1.0 12.626808937259163 -6.766456010915152 0.8051261209468823 0.995540988101964 1.2556554580245327 0.17453811133453445 0.18219929224276624 1.0353625436450844 1.4662858005698909 0.1264926453393485 0.1204930088056387 1.7121585900857553e-07 6.766456010915152 0.2601144699225687 T(ph)SLSPAEILEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSLSPAEILEEK 12 0 A0A2R8Y2X6;A1A5D9;A1A5D9-2 A0A2R8Y2X6;A1A5D9-2 CCDC64B Bicaudal D-related protein 2 1 T(0.609)S(0.388)LS(0.003)PAEILEEK;T(0.961)S(0.039)LSPAEILEEK 138.89 9.1081e-05 1930300.0 14537.9 21657.0 15464.4 16124.400000000001 19390.8 12245.7 16652.1 12764.4 12501.900000000001 13237.5 True False 16998.879333386598 23806.96383387321 15833.129945063585 15221.002144010132 15591.311938022502 11603.513934677192 15074.692537236211 12429.348024999728 12684.716636228894 15637.353962007666 1.0870687825246443 1.522441961198444 1.0125197641194013 0.9733745351669407 0.9970556384349278 0.7420381966711859 0.964018118018017 0.7948498227512102 0.8111805019600844 1.0 13.93270879060586 -5.4621983867328705 4.7338536047341195 0.8948726454120915 1.3049916656504947 0.6032804802272654 0.13001136852773035 0.12829004216720283 5.790993833311543 0.033512146990858506 0.0706005408652988 3.449861128750551e-06 5.4621983867328705 0.4101190202384032 T(ph)SLSPAEILEEK ddPTM_PC-9_Lapatinib_30min_R1 1 TSLSPAEILEEK 12 0 A0A2R8Y2X6;A1A5D9;A1A5D9-2 A0A2R8Y2X6;A1A5D9-2 CCDC64B Bicaudal D-related protein 2 1 T(0.599)S(0.401)LSPAEILEEK 129.54 0.00042161 1361200.0 10716.0 11180.0 11065.0 11444.0 12702.0 12131.0 14680.0 12505.0 12347.0 11160.0 True False 10563.187874926276 11154.113396897152 10155.278412135185 12285.62993606487 11954.893333092838 11612.185408742185 15440.058570208343 13086.027951746915 10956.350840325975 13088.991130234735 0.8070284233386014 0.8521751818695835 0.7758641067971342 0.9386231386226436 0.9133548349251911 0.8871719212887826 1.17962174598337 0.9997736129195645 0.8370661062652494 1.0 13.676066281454544 -6.247773607437244 1.141300663328817 0.9943552922346856 0.8147009302305396 0.3851309315096485 0.08824341403776452 0.5254645529466664 1.4155251710936612 0.03860139858561256 0.05815583065104475 5.652315465289142e-07 6.247773607437244 -0.17965436200414597 T(ph)SLSPTSK ddPTM_PC-9_AZD4547_30min_R2 1 TSLSPTSK 8 0 Q8NDI1-3;Q8NDI1-2;Q8NDI1;H7C0Q4 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 T(0.651)S(0.004)LS(0.323)PT(0.022)SK 96.14299999999999 0.015184999999999999 7907300.0 47229.0 46247.0 44821.0 68207.0 60431.0 51034.0 48908.0 54636.0 46470.0 47471.0 True False 62246.839575773265 61195.43834062373 44226.64425447884 52482.92993764532 52041.19876498969 47842.83591239334 53260.717252649694 46193.261610379464 48926.30932961472 45809.05473904787 1.358832657219485 1.3358808359880963 0.9654563820715519 1.1456889961300294 1.1360461171146916 1.0443969251260683 1.1626678951585088 1.0083871381655927 1.0680488739251301 1.0 15.483345172980398 -5.24413893567747 23.853060191793407 1.0746165804461518 1.347356900295686 0.7602802881084414 0.0629822130716043 205.22053864380572 282946.3816332217 0.015493929944800105 0.040738783117434556 5.699818995060037e-06 5.24413893567747 0.2727403198495342 T(ph)SMCSIQSAPPEPATLK ddPTM_PC-9_AZD4547_30min_R2 2 TSMCSIQSAPPEPATLK 17 0 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;P20810-2;E9PCH5;P20810-3;H0Y7F0;H0Y9H6;E7EQ12;E7EQA0;H0YD33;A0A0A0MR45 P20810-6 CAST Calpastatin 1 T(0.836)S(0.164)MCSIQSAPPEPATLK;T(0.986)S(0.014)MCSIQSAPPEPATLK 195.46 1.5258e-11 12465000.0 37380.0 40026.0 45129.0 70752.0 73378.0 71961.0 48953.0 60402.0 52258.0 69493.0 True False 49266.062447699565 52963.621748909274 44530.55997323523 54441.21950750328 63190.73129647721 67461.26729419094 53309.72216547313 51068.25879987811 55020.251193178534 67060.07122202283 0.7346556833288952 0.7897936996451591 0.6640398550398674 0.8118276422233285 0.9423003904553726 1.00598263713201 0.7949547501817442 0.7615300411895038 0.8204621646019015 1.0 16.033166394915035 -5.992871514689425 9.49762568752258 0.8769570439609222 0.735775535030849 0.4242690629752688 0.08207463550562605 0.16961478490194956 165.7272596835706 0.025155349472639556 0.03634038944426555 1.0165493928592505e-06 5.992871514689425 -0.1411815089300732 T(ph)SMCSIQSAPPEPATLK ddPTM_PC-9_Lapatinib_30min_R1 2 TSMCSIQSAPPEPATLK 17 0 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810;P20810-8;P20810-4;B7Z574;E7EVY3;E7ES10;E9PDE4;P20810-2;E9PCH5;P20810-3;H0Y7F0;H0Y9H6;E7EQ12;E7EQA0;H0YD33;A0A0A0MR45 P20810-6 CAST Calpastatin 1 T(0.492)S(0.492)MCS(0.016)IQS(0.001)APPEPATLK;T(0.794)S(0.202)MCS(0.004)IQSAPPEPATLK 105.39 0.002771 11032100.0 46013.0 49353.0 60363.0 60752.0 53413.0 62454.0 48776.0 41616.0 54726.0 46838.0 True False 45356.84618224924 49238.7261607393 55400.187147918296 65219.904742730985 50271.35235399836 59782.988007384745 51301.38261719905 43549.63128667728 48562.18158967189 54933.88589228802 0.8256624385025844 0.8963270185780132 1.0084884083486207 1.1872436053515556 0.9151246364141843 1.088271602060059 0.9338749987173414 0.7927644400046177 0.8840114039063341 1.0 15.745408727827584 -7.5230864154210595 24.99874356625922 0.8756966805279435 0.9913618105600835 0.13345783087876528 0.10618508005132767 13.098040346776378 1575996.6916519965 0.051005980502400954 0.029819069115123543 2.9985658084160226e-08 7.5230864154210595 0.11566513003214007 T(ph)SMGGTQQQFVEGVR ddPTM_PC-9_AZD4547_30min_R2 5 TSMGGTQQQFVEGVR 15 0 A0A2R8Y6G0;A0A2R8Y804;A0A2R8Y543;A0A2R8Y5C3;A0A2R8Y750;A0A2R8Y5Z1;B4DGU4;A0A2R8YCH5;A0A2R8Y5A3;P35222 A0A2R8Y6G0 CTNNB1 Catenin beta-1 1 T(0.92)S(0.08)MGGTQQQFVEGVR;T(0.602)S(0.398)MGGTQQQFVEGVR;T(0.535)S(0.411)MGGT(0.054)QQQFVEGVR;T(0.998)S(0.002)MGGTQQQFVEGVR;T(0.999)S(0.001)MGGTQQQFVEGVR 193.3 3.7739e-09 93774000.0 169880.0 258091.0 223798.0 214236.0 218404.0 232263.0 239817.0 304830.0 234075.0 232368.0 True False 223898.30627649042 341513.8685054146 220830.2922929846 164847.20011320518 188082.37452745828 217739.55789317377 261160.24841291198 257725.52779654352 246447.72662641658 224232.8670473141 0.9985079762158457 1.5230321629583128 0.9848257090981604 0.7351607384051407 0.8387814730468218 0.9710421168865927 1.1646831789284755 1.1493655287481221 1.0990704880672781 1.0 17.774638231843774 -5.325156944410962 24.921347251747218 0.9888505211172497 1.260770743627292 0.2808435352857671 0.1713856309249909 234.9902292981703 91909.24824377213 0.047520109249575795 0.09892101751947882 4.7298030346316255e-06 5.325156944410962 0.2719202225100422 T(ph)SMGGTQQQFVEGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TSMGGTQQQFVEGVR 15 0 A0A2R8Y6G0;A0A2R8Y804;A0A2R8Y543;A0A2R8Y5C3;A0A2R8Y750;A0A2R8Y5Z1;B4DGU4;A0A2R8YCH5;A0A2R8Y5A3;P35222 A0A2R8Y6G0 CTNNB1 Catenin beta-1 1 T(0.588)S(0.412)MGGTQQQFVEGVR;T(0.597)S(0.403)MGGTQQQFVEGVR;T(0.5)S(0.5)MGGTQQQFVEGVR;T(0.702)S(0.297)MGGT(0.001)QQQFVEGVR 116.58 0.00054245 119607000.0 223810.0 315834.0 264125.0 216871.0 352546.0 190957.0 199808.0 194722.0 181211.0 181013.0 True False 261696.61255100538 347187.9122458105 270422.74169964093 204720.4209752683 283467.1420726371 180942.87875941393 180880.73975535185 189610.75382501315 183860.86805746885 213829.2240018802 1.2238580286327199 1.6236691400178194 1.2646668993068182 0.95740150548116 1.325670723428078 0.8462027564474671 0.8459121553645135 0.8867391943738517 0.8598491105025576 1.0 17.70609951384398 -6.039215742343711 0.8307088898237269 0.8782137547124268 1.4495975979924929 0.5879003969425459 0.16078462137047655 0.47706085017342686 0.6686057648354914 0.07868124640318985 0.1772475456309157 9.136592546820071e-07 6.039215742343711 0.5713838432800661 T(ph)SMGGTQQQFVEGVR ddPTM_PC-9_Lapatinib_30min_R1 7 TSMGGTQQQFVEGVR 15 0 A0A2R8Y6G0;A0A2R8Y804;A0A2R8Y543;A0A2R8Y5C3;A0A2R8Y750;A0A2R8Y5Z1;B4DGU4;A0A2R8YCH5;A0A2R8Y5A3;P35222 A0A2R8Y6G0 CTNNB1 Catenin beta-1 1 T(0.587)S(0.413)MGGTQQQFVEGVR;T(0.5)S(0.5)MGGTQQQFVEGVR;T(0.705)S(0.295)MGGTQQQFVEGVR;T(0.565)S(0.435)MGGTQQQFVEGVR;T(0.836)S(0.164)MGGTQQQFVEGVR;T(0.999)S(0.001)MGGTQQQFVEGVR;T(0.998)S(0.002)MGGTQQQFVEGVR 308.78 7.679999999999999e-121 125739200.0 401404.0 543773.0 285077.1 248536.2 311075.0 230936.4 209226.3 221577.2 334220.0 202650.4 True False 395679.9053515214 542513.9270278125 261639.16126742953 266814.3812404583 292778.18009698106 221059.78851104205 220059.01406185154 231872.4856193376 296576.6241073741 237678.25162531502 1.6647711881324596 2.282556032442766 1.1008123775661536 1.1225864353002502 1.2318257059485933 0.9300800010071139 0.9258693740677666 0.975573002719955 1.2478071598023563 1.0 17.85865037221535 -5.2758164598428685 24.17617402474581 1.0639140891030228 1.9736635491038919 0.8110607468514276 0.17507171998685753 166.5941263492186 280141.17173426645 0.04415029507821179 0.09265071186856398 5.298873358840936e-06 5.2758164598428685 0.9097494600008691 T(ph)SMKNMEKELLCPVCQEMY(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 TSMKNMEKELLCPVCQEMYK 20 2 A0A0A0MS35 A0A0A0MS35 TRIM46 2 T(0.846)S(0.235)MKNMEKELLCPVCQEMY(0.92)K 40.844 0.040875 7798900.0 22195.0 28942.0 15526.0 21421.0 19655.0 20819.0 15921.0 17568.0 16287.0 16591.0 True False 21878.495229935488 28874.986577191186 14249.51221209317 22996.37179836121 18498.931543216793 19928.61990145936 16745.31147794872 18384.273415137133 14452.586550286629 19458.732243882125 1.1243535784205132 1.4839089317480874 0.7322939661998409 1.1818021600863196 0.9506750651257306 1.0241479070521138 0.860555110583501 0.9447826911189035 0.7427301208089011 1.0 14.248130099686811 -5.054711344686101 0.5737734050313809 0.8949290702415429 1.4499359188592214 0.2964013068101693 0.1771142732637069 3.4532217341971263 1.0761464174748663 0.09521644588013563 1.2229910726636357 8.816346598081461e-06 5.054711344686101 0.5550068486176785 T(ph)SNRYSPESQAQSVHHQRPGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSNRYSPESQAQSVHHQRPGSR 22 2 O75376-2;O75376;A0A088AWL3;E7EVK1;J3KS29;J3QKP0 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 T(0.358)S(0.093)NRY(0.247)S(0.286)PES(0.014)QAQS(0.001)VHHQRPGSR 41.513000000000005 0.029844 1621800.0 816.67 902.82 5866.3 5164.1 6550.5 6292.1 2199.9 3052.3 3724.8 3140.5 True False 954.9161010322558 992.4460030704812 6006.174840066642 4874.772219238091 5266.976548157704 5962.131199391002 1991.5095461032504 2972.1803591791763 3779.268153370716 3709.847789815679 0.2574003450097612 0.26751663661106434 1.618981473190051 1.3140086859143862 1.4197284758195943 1.6071093848535565 0.5368170498990195 0.8011596506299917 1.018712456005772 1.0 11.857144280838938 -5.241151311532329 23.982617584877772 1.1652990779277628 0.262457979318132 0.5502337800059135 0.3262396101316466 392.97509689902364 464534.27008944337 0.09144624733921623 0.2412048894885417 5.739164704647563e-06 5.241151311532329 -0.9028410986096308 T(ph)SPADHGGSVGSESGGSAVDSVAGEHSVSGR ddPTM_PC-9_AZD4547_30min_R2 3 TSPADHGGSVGSESGGSAVDSVAGEHSVSGR 31 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;A0A0A0MSW0;X6RE05 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 T(0.486)S(0.486)PADHGGS(0.027)VGS(0.002)ESGGSAVDSVAGEHSVSGR;T(0.793)S(0.205)PADHGGS(0.001)VGSESGGSAVDSVAGEHSVSGR;T(0.493)S(0.493)PADHGGS(0.014)VGSESGGSAVDSVAGEHSVSGR 196.86 2.0138999999999998e-36 28282700.0 5856.7 6640.799999999999 24331.9 27743.6 22598.6 25664.5 16134.7 28828.3 16462.399999999998 24370.6 True False 7719.008773072289 8787.308732078058 24009.243107818973 21347.741654347155 19461.174470230446 24059.694757879413 17570.65704294444 24373.548643431113 17332.568855344296 23517.392711833316 0.32822553365740637 0.37365148593434516 1.0209143250704902 0.9077427041308687 0.8275226216058428 1.0230596160335932 0.7471345679448284 1.03640522323578 0.7370106485751295 1.0 14.521440502214642 -5.252710288768822 24.577805324810846 0.9086154953354911 0.3509383777110338 0.8162820334106368 0.10654704459576142 178.4713342048861 502503.8480814717 0.024886756664203306 0.06365022359110702 5.588428659817081e-06 5.252710288768822 -0.5576771176244573 T(ph)SPADHGGSVGSESGGSAVDSVAGEHSVSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSPADHGGSVGSESGGSAVDSVAGEHSVSGR 31 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;A0A0A0MSW0;X6RE05 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 T(0.499)S(0.499)PADHGGS(0.001)VGSESGGSAVDSVAGEHSVSGR;T(0.497)S(0.497)PADHGGS(0.003)VGS(0.003)ES(0.001)GGSAVDSVAGEHSVSGR;T(0.5)S(0.5)PADHGGSVGSESGGSAVDSVAGEHSVSGR 206.23 5.7022e-46 22512200.0 10690.400000000001 19740.7 34829.2 24777.3 36189.5 30186.7 38450.2 26900.9 35053.8 21438.6 True False 12500.073574975491 21700.426234258703 35659.66021847655 23389.108210090417 29098.42726349947 28603.656311351733 34807.91870065875 26194.779878859586 35566.39550972574 25325.248472135772 0.4935814781335219 0.8568692330160038 1.4080675361472272 0.9235490121972306 1.1489888162603876 1.1294521490212839 1.3744354271175794 1.0343345656679546 1.4043848591992234 1.0 14.628288803275154 -4.957019835457251 3.51071883393827 1.1742842816283527 0.506677671618434 0.6331214750355749 0.16402396288889895 0.14333299099672453 3.488602359595534 0.039515888104392834 0.2006146189459239 1.1040281946605114e-05 4.957019835457251 -0.6676066100099187 T(ph)SPADHGGSVGSESGGSAVDSVAGEHSVSGR ddPTM_PC-9_Lapatinib_30min_R1 2 TSPADHGGSVGSESGGSAVDSVAGEHSVSGR 31 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;A0A0A0MSW0;X6RE05 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 T(0.496)S(0.496)PADHGGS(0.004)VGS(0.002)ES(0.002)GGSAVDSVAGEHSVSGR;T(0.5)S(0.5)PADHGGS(0.001)VGSESGGSAVDSVAGEHSVSGR 128.55 1.1772e-14 14449200.0 12174.5 10580.3 16759.9 8623.0 14291.1 19336.3 13481.5 17028.4 22030.6 10184.0 True False 12000.889397470131 10555.80196540169 15381.965717084908 9257.164185484748 13450.52559538363 18509.33152411685 14179.506104513883 17819.60162923049 19549.281835497317 11944.290830672977 1.004738545603043 0.8837529255646017 1.2878090407497422 0.775028364322168 1.126104997447202 1.5496383825973852 1.1871367087027775 1.4918928115405308 1.6367051097997964 1.0 13.54403357863935 -6.579443298886458 6.1258478713913185 1.3897590107280717 0.9954789355810522 0.4323778075443515 0.20904964156272202 0.1798006851244473 13.985022914118717 0.0663830746716181 0.06663281583281432 2.633641767231403e-07 6.579443298886458 -0.39428007514701957 T(ph)SPAKQQAPPVR ddPTM_PC-9_AZD4547_30min_R2 3 TSPAKQQAPPVR 12 1 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 1 T(0.988)S(0.012)PAKQQAPPVR;T(0.992)S(0.008)PAKQQAPPVR;T(0.971)S(0.029)PAKQQAPPVR 177.16 0.0015785999999999999 53531700.0 91227.0 37212.0 92390.0 282427.0 212646.0 99595.0 62660.0 65228.0 61534.3 110021.0 True False 120235.28836052142 49240.05127967846 91164.84823344633 217317.8186036528 183123.77343714304 93367.30890572563 68236.61861149553 55148.511390325635 64786.877473236775 106169.1982777862 1.132487485173732 0.4637884817670415 0.858675112106604 2.046900816139272 1.7248295777651932 0.8794199298880916 0.6427157755581611 0.5194398402259045 0.6102229132758945 1.0 16.69600574776014 -6.990990046668925 24.85318570261541 0.6684793053441799 1.2326829874695735 0.2783602709098334 0.42219131079674715 278.340128699223 767773.2666280179 0.16932146007540375 0.1491179429907623 1.0209628822668579e-07 6.990990046668925 0.5642036821253936 T(ph)SPAKQQAPPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSPAKQQAPPVR 12 1 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 1 T(0.998)S(0.002)PAKQQAPPVR 161.87 0.0067065 5936800.0 14629.0 1343.3 4023.9 19699.0 16137.0 29210.0 14708.0 27240.0 25420.0 18184.0 True False 17105.400764079597 1476.6539464395762 4119.84503672573 18595.32889501968 12975.070690423765 27678.176178733833 13314.751763301325 26524.978863165732 25791.71941008472 21480.615255535213 0.7963180086134547 0.06874355919852276 0.19179362358646182 0.8656795289058566 0.604036268797296 1.2885187807458918 0.6198496460603159 1.2348332926046273 1.2006974243178907 1.0 14.390747695656646 -6.206111486878638 1.3741027839022424 1.051676467665074 0.33930734304556087 0.5003143223868102 0.283322749273449 0.3375227677189992 1.285004630537294 0.10546892694908357 0.15576646479847497 6.221405561948433e-07 6.206111486878638 -0.7123691246195132 T(ph)SPAPWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSPAPWK 7 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(0.987)S(0.013)PAPWK 98.62899999999999 0.029588 11102000.0 165600.0 289110.0 186730.0 173560.0 230170.0 146040.0 203640.0 163750.0 131770.0 122310.0 True False 193632.80925091114 317810.9301385735 191182.35137746856 163835.99588911235 185069.84078917032 138381.40531127297 184349.744974074 159451.73600746682 133696.88696565185 144483.83479457296 1.340169365840948 2.199629672000587 1.3232092825421717 1.1339399741296614 1.280903438452492 0.9577639291483617 1.2759195188595485 1.1035956806806464 0.925341489971816 1.0 17.140548563935866 -5.474781134797744 6.445381084514116 1.1182191577448046 1.773811403134811 0.5861478207902423 0.22331029175872474 0.1358080497104769 13.847655825831906 0.05472391153008106 0.11289822370683161 3.3513428946060978e-06 5.474781134797744 0.6555922453900063 T(ph)SPDPSPVSAAPSK ddPTM_PC-9_AZD4547_30min_R2 2 TSPDPSPVSAAPSK 14 0 Q13469-3;Q13469-4;Q13469-2;Q13469;Q13469-5 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 T(0.5)S(0.5)PDPSPVSAAPSK;T(0.5)S(0.5)PDPSPVSAAPSK 113.54 0.00048722 96791000.0 191073.0 213245.0 352340.0 396840.0 386340.0 340400.0 377170.0 384620.0 346880.0 372700.0 True False 251830.23943470523 282172.27601674286 347667.7413851334 305354.66911688214 332703.3597138244 319114.7341885543 410737.399324893 325185.816688341 365215.36863044463 359651.88644105074 0.7002055290928714 0.7845705435024674 0.9666784868709938 0.8490284094948901 0.9250705258523831 0.8872878086261873 1.1420415540965487 0.9041682497657106 1.0154690755120113 1.0 18.45624164576534 -3.5879565652698475 0.4226861770372925 1.0008050976515002 2.235327769623971e-15 0.6097702246131869 0.07390431361031702 9.791439291314214 0.6240855676974127 0.05220495625734948 6.0864450921162145 0.0002582518460974412 3.5879565652698475 -1.000805097651498 T(ph)SPDPSPVSAAPSK ddPTM_PC-9_Lapatinib_30min_R1 2 TSPDPSPVSAAPSK 14 0 Q13469-3;Q13469-4;Q13469-2;Q13469;Q13469-5 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 T(0.986)S(0.014)PDPSPVSAAPSK;T(0.87)S(0.13)PDPSPVSAAPSK 241.76 2.3386e-27 96418000.0 723940.0 685560.0 699840.0 748110.0 750070.0 693880.0 557340.0 523710.0 727830.0 478000.0 True False 713616.4828456648 683972.6279406797 642301.8566605239 803128.5050218017 705952.3572943588 664204.3699132826 586196.3381144352 548043.4784973521 645854.1210103221 560621.663105037 1.272902083186113 1.2200253271563855 1.145695749791573 1.432567733065515 1.2592313207884245 1.1847640104282566 1.0456184209289228 0.9775638626983841 1.1520320449859538 1.0 19.09666796738083 -7.099478968136613 2.7692016426915456 1.0406254439366383 1.2649721482701133 0.6366959972120498 0.07916897511213668 0.18751841172749215 2.79327851561492 0.03419943377866124 0.025807246622303978 7.952817782325224e-08 7.099478968136613 0.22434670433347503 T(ph)SPDSLRR ddPTM_PC-9_AZD4547_30min_R2 1 TSPDSLRR 8 1 Q9BRL6-2;Q9BRL6 Q9BRL6-2 SRSF8 Serine/arginine-rich splicing factor 8 1 T(0.987)S(0.013)PDSLRR 108.57 0.012929 11375000.0 36714.0 32161.0 41693.0 54274.0 41091.0 36915.0 33190.0 50397.0 32137.0 45278.0 True False 48388.28830136012 42556.41430736698 41140.12357827775 41761.96782494115 35386.22393228959 34606.69921436688 36143.84570245037 42609.30165785005 33835.696211014176 43692.831001550614 1.1074651651581666 0.9739907745015811 0.9415760580223729 0.9558082382773289 0.8098862701534211 0.792045249096785 0.8272259973533796 0.9752012099270447 0.7743992649460819 1.0 15.415108965294461 -4.655752425058568 0.8276815626285382 0.8626679886781675 1.274730079180746 0.4820515456176373 0.07457609793309777 2.490740801836426 1.1431018559821524 0.027375133484863826 0.989175401722147 2.2092637922660152e-05 4.655752425058568 0.4120620905025786 T(ph)SPDSLRR ddPTM_PC-9_Lapatinib_30min_R1 1 TSPDSLRR 8 1 Q9BRL6-2;Q9BRL6 Q9BRL6-2 SRSF8 Serine/arginine-rich splicing factor 8 1 T(0.529)S(0.471)PDSLRR 70.908 0.031287 3285100.0 13746.0 11790.0 12697.0 14123.0 17259.0 13280.0 13562.0 14051.0 10995.0 11585.0 True False 13549.979519292328 11762.700979375448 11653.101671837358 15161.652532946895 16243.859552499536 12712.045357192006 14264.174000624362 14703.860755697395 9756.627317517135 13587.451813957832 0.9972421396463015 0.8657032341628699 0.8576370191698935 1.1158569495254402 1.1955044827325816 0.9355724333928046 1.0498049373740086 1.0821647029204344 0.7180615947056793 1.0 13.729987298490178 -5.746878674932334 24.99675947884261 1.0230809218164245 0.902745033240913 0.13031873602460375 0.12494245276947606 454.2531198747942 779822.4155118117 0.03420582334787447 0.058918872846292304 1.791106149878918e-06 5.746878674932334 -0.12033588857551147 T(ph)SPDTLR ddPTM_PC-9_AZD4547_30min_R2 1 TSPDTLR 7 0 J3QL05;J3KP15;Q01130-2;Q01130 J3QL05 SRSF2 Serine/arginine-rich splicing factor 2 1 T(0.949)S(0.051)PDTLR 148.99 0.0027305999999999997 386690000.0 150490.0 144870.0 149290.0 163700.0 164700.0 172140.0 162970.0 190230.0 150320.0 140250.0 True False 198342.6896135448 191696.39441274383 147310.317055647 125961.49413978834 141834.24792894023 161376.0585875959 177474.01428527726 160834.32455052529 158265.6083156376 135339.89018877732 1.4655153727174504 1.4164071963214857 1.0884471448157145 0.9307048643536829 1.0479855401914715 1.1923761602178213 1.3113208089479726 1.1883733932855076 1.1693936510136265 1.0 17.046227597532642 -5.230859001101147 6.512267433077624 1.1233504975619728 1.4449190453793455 0.6123212844415322 0.1033157976164705 0.14763072330827062 21.557203862615232 0.030097645544555792 0.07843329695931422 5.876801189416145e-06 5.230859001101147 0.32156854781737265 T(ph)SPDTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSPDTLR 7 0 J3QL05;J3KP15;Q01130-2;Q01130 J3QL05 SRSF2 Serine/arginine-rich splicing factor 2 1 T(0.949)S(0.051)PDTLR;T(0.681)S(0.313)PDT(0.006)LR;T(0.947)S(0.053)PDTLR 148.99 0.0027305999999999997 1114540000.0 4343700.0 6548000.0 5182300.0 5841900.0 5933700.0 3966520.0 5534100.0 3761460.0 4079430.0 3756490.0 True False 5079002.618014394 7198042.1657755785 5305865.685982193 5514597.282695335 4771034.08042186 3758508.7085406105 5009869.9845856605 3662725.6605963116 4139083.946226678 4437511.900641517 1.144560900733616 1.6220896590125158 1.195684835282389 1.2427228154358545 1.0751597262718613 0.846985606505586 1.1289817575162784 0.8254007521797977 0.9327488103475968 1.0 22.081319557893302 -6.1643537208560595 1.3883094829579625 0.9425607178470736 1.3675085014558097 0.5832235960000959 0.14186940664991643 0.2743732378625232 1.0655899544861873 0.050492330258501555 0.07730393357962094 6.849301425349053e-07 6.1643537208560595 0.4249477836087361 T(ph)SPDTLRR ddPTM_PC-9_AZD4547_30min_R2 2 TSPDTLRR 8 1 J3QL05;J3KP15;Q01130-2;Q01130 J3QL05 SRSF2 Serine/arginine-rich splicing factor 2 1 T(0.967)S(0.027)PDT(0.007)LRR;T(0.893)S(0.106)PDT(0.001)LRR 86.898 0.010298 676200000.0 57545.0 46772.0 66312.0 74526.0 70970.0 65393.0 49533.0 63182.0 57473.0 58885.0 True False 75843.11298964338 61890.13432368919 65432.659552508936 57345.18211522208 61117.040531371604 61303.965372479826 53941.341041864245 53418.67367792289 60510.90544654504 56823.45407319906 1.3347149381652075 1.0891652986100302 1.1515079577566623 1.0091815615670061 1.0755601103136325 1.0788496822722013 0.9492795170877483 0.9400814249888755 1.0648931226284812 1.0 15.794198909472158 -1.5228787452836092 0.5351946041134134 1.00265494369615 13.276058485666667 0.7357185345003768 0.055669943598609876 65.2789033112181 0.6261198802545999 0.02852571396928001 915.492681492417 0.029999999999774003 1.5228787452836092 12.273403541970517 T(ph)SPDTLRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSPDTLRR 8 1 J3QL05;J3KP15;Q01130-2;Q01130 J3QL05 SRSF2 Serine/arginine-rich splicing factor 2 1 T(0.569)S(0.431)PDTLRR;T(0.997)S(0.002)PDTLRR;T(0.595)S(0.4)PDT(0.005)LRR 75.652 0.02213 1040310000.0 68716.0 69703.5 56792.0 93025.0 113098.0 98036.0 98017.0 85830.0 92512.0 71953.0 True False 80348.26159713528 76623.2028256167 58146.13666485936 87813.11084111927 90937.25878078605 92894.81957748537 88732.12017837276 83577.05344440206 93864.81298449104 84997.50932036528 0.9453013651764023 0.9014758601550915 0.6840922414055682 1.0331256944264293 1.0698814530909746 1.0929122549621333 1.04393788580241 0.983288264711271 1.1043242764997252 1.0 16.3751329461668 -5.898472968354956 10.22921230395017 1.0502603293081956 0.8496531787649175 0.627829926145131 0.07171657152978374 0.2119051593840653 19.720150910678623 0.020201354083847264 0.02999553166215343 1.2633597362343906e-06 5.898472968354956 -0.20060715054327805 T(ph)SPDTLRR ddPTM_PC-9_Lapatinib_30min_R1 2 TSPDTLRR 8 1 J3QL05;J3KP15;Q01130-2;Q01130 J3QL05 SRSF2 Serine/arginine-rich splicing factor 2 1 T(0.98)S(0.013)PDT(0.007)LRR;T(0.913)S(0.087)PDTLRR 79.48899999999999 0.017522 917250000.0 60949.0 69277.0 71760.0 69773.0 66815.0 69818.0 63854.0 60944.0 69654.0 47232.0 True False 60079.85608332229 69116.59336286625 65860.16980161058 74904.33917590465 62885.07306334411 66832.04689370713 67160.04767997855 63775.68072701029 61808.833030862916 55395.98826731601 1.0845524732477747 1.2476822875573732 1.188897822055257 1.3521617994149713 1.135191825803146 1.2064420002980336 1.2123630208724594 1.1512689406181846 1.1157637035483763 1.0 15.757493880798389 -8.545596232727299 1.0020294514101968 1.0004858761670503 1.2105815624334173 0.47306354378986293 0.06629188922024515 0.5031966600056542 1.108242325512864 0.06141326337924545 0.020393180695537746 2.847106856823695e-09 8.545596232727299 0.210095686266367 T(ph)SPENVQDR ddPTM_PC-9_AZD4547_30min_R2 2 TSPENVQDR 9 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 T(0.985)S(0.015)PENVQDR;T(0.92)S(0.08)PENVQDR 160.72 0.00035276 221905000.0 78857.0 69011.0 94014.0 123656.0 107161.0 90548.0 86337.0 96905.0 85933.0 89370.0 True False 103931.88567250528 91317.45616634125 92767.3129323436 95149.01966615554 92283.54488350451 84886.01924590263 94020.82574306903 81930.55890537046 90475.24294430349 86241.18350211105 1.2051305588815486 1.0588613520604797 1.0756730040708777 1.1032898181856055 1.070063525754439 0.9842863443986104 1.0902079717026094 0.9500166344930195 1.049095562818764 1.0 16.396089356119816 -1.5228787452803376 0.31616578813653057 1.0058378622292805 2.541910379371891 0.5490433338036539 0.04541050351289515 44.057681255170216 0.6290446150865118 0.04223670077265563 38.96955557403195 0.029999999999999995 1.5228787452803376 1.5360725171426104 T(ph)SPENVQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSPENVQDR 9 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 T(0.999)S(0.001)PENVQDR 136.5 0.0024406 100850000.0 36664.0 44611.0 40761.0 38831.0 55203.0 38039.0 40150.0 33272.0 40202.0 32864.0 True False 42870.49105299158 49039.68525617205 41732.896826953314 36655.42496180056 44386.36842805126 36044.167876167616 36346.701339172454 32398.64525459801 40789.87819528822 38821.983048719136 1.1042839053118905 1.2631937218310139 1.074981068704841 0.9441924930985705 1.143330786898474 0.9284473652707144 0.9362402042564296 0.8345437999377764 1.0506902273410275 1.0 15.244586193156993 -5.732961184488463 0.8318861380209628 0.9470605965997448 1.2066452850012803 0.434144148164225 0.08923478032673346 0.7596454061865585 0.927309851197796 0.0399407447163278 0.14205864921961023 1.849433906630168e-06 5.732961184488463 0.2595846884015355 T(ph)SPGQFGALGACYNPGGQLGGASAGAYHAR ddPTM_PC-9_AZD4547_30min_R2 1 TSPGQFGALGACYNPGGQLGGASAGAYHAR 30 0 O00358 O00358 FOXE1 Forkhead box protein E1 1 T(0.5)S(0.5)PGQFGALGACYNPGGQLGGASAGAYHAR 130.43 5.2949e-15 8257500.0 6568.1 5961.1 5928.2 10201.0 9101.6 7651.6 7215.2 8214.3 8726.5 7018.3 True False 8656.619175033054 7887.90899933601 5849.588194582932 7849.31705387892 7837.999945051886 7173.144242412287 7857.3388223055135 6944.968680835712 9187.764974497157 6772.591453204261 1.2781841684747453 1.1646810609850191 0.8637149066204731 1.1589828071151755 1.1573117910934312 1.0591432086189867 1.1601672530517155 1.025452181609138 1.3566099532181621 1.0 12.725492254550202 T(ph)SPGRVDLPGSSTTLTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSPGRVDLPGSSTTLTK 17 1 H7BZX1;H7C1R7;H7BZK1;H7BXR3;O94875-9;O94875-5;O94875-3;O94875-8;O94875-2;O94875-4;O94875-12;O94875-10;O94875-7;O94875;O94875-11 H7BZX1 SORBS2 Sorbin and SH3 domain-containing protein 2 1 T(0.848)S(0.152)PGRVDLPGSSTTLTK;T(0.5)S(0.5)PGRVDLPGSSTTLTK 74.047 0.0071115 12125400.0 52796.0 49172.0 39117.0 51833.0 54503.0 55371.0 48901.0 51295.0 37696.0 42496.0 True False 61733.32003146807 54053.47119357314 40049.69763204859 48928.9650548533 43823.52840305919 52467.24728492543 44268.74326741899 49948.56060154498 38247.232686174415 50200.18840184912 1.229742795730108 1.0767583332731494 0.7977997475119708 0.9746769207952019 0.8729753771490816 1.045160366031471 0.8818441658634962 0.994987512829835 0.7618942060537284 1.0 15.615405158185723 -4.995748920770882 4.1302936022311085 0.9198678039306745 1.2114778430434137 0.5711030074638115 0.0868316232636168 0.13192781531137934 5.326835043087182 0.02066688793509683 0.08342925853107584 1.009836535446503e-05 4.995748920770882 0.2916100391127392 T(ph)SPINEDIR ddPTM_PC-9_Lapatinib_30min_R1 1 TSPINEDIR 9 0 D6RA28;A0A590UJ84;B1AKN3;Q9P2R6-2;Q9P2R6 D6RA28 RERE Arginine-glutamic acid dipeptide repeats protein 1 T(0.653)S(0.347)PINEDIR 163.46 0.00053207 12190000.0 57203.0 92465.0 90155.0 63205.0 93849.0 96818.0 90887.0 95005.0 83557.0 73028.0 True False 56387.274730254576 92250.90297353249 82742.80390836408 67853.30654569916 88328.98633423312 92677.31983378119 95592.6841464935 99419.27913280415 74145.93076578257 85650.79249630673 0.6583392060579708 1.0770583702130994 0.9660483166216115 0.7922087416602128 1.0312687572393666 1.0820369214654662 1.1160747187554096 1.1607514213845844 0.8656771128997989 1.0 16.386178974664354 -6.419037001011695 6.820344813369083 1.0591105811374666 0.8950596141680115 0.2920866363764347 0.1264271764790599 0.338974842476657 19.312888409028464 0.03875851047732453 0.04388923621533837 3.8103335873913336e-07 6.419037001011695 -0.1640509669694551 T(ph)SPINLGLNVNDLLK ddPTM_PC-9_Lapatinib_30min_R1 1 TSPINLGLNVNDLLK 15 0 P50616 P50616 TOB1 Protein Tob1 1 T(0.761)S(0.239)PINLGLNVNDLLK 130.64 0.00013478 0.0 608.94 708.83 591.46 0.0 1162.7 529.2 425.41 656.79 987.53 0.0 True False 600.2564039340805 707.1887476853858 542.8324419016247 0.0 1094.312271956152 506.5673496254523 447.4356482528836 687.3068611297771 876.3039722480847 0.0 0.0 T(ph)SPKPAVVETVTTAK ddPTM_PC-9_AZD4547_30min_R2 1 TSPKPAVVETVTTAK 15 1 H0YI94;H0YIP0;P56192 H0YI94 MARS Methionine--tRNA ligase, cytoplasmic 1 T(0.783)S(0.217)PKPAVVETVTTAK 69.024 0.019173 10486000.0 39743.0 42666.0 44961.0 38532.0 42193.0 50632.0 51168.0 42996.0 45656.0 46214.0 True False 52380.447294246245 56456.95012089545 44364.78776300447 29649.042713465613 36335.23025419422 47465.973035942676 55721.85287444958 36351.95614978907 48069.282951428686 44596.06192644682 1.1745532011467374 1.265962681054911 0.9948140227308906 0.6648354458374907 0.8147632029510283 1.0643534649814879 1.2494792245636566 0.8151382561479326 1.077881787650002 1.0 15.444628697541905 -5.328028473673876 5.6073762860961995 0.9501180115202077 1.2196732926415748 0.3071656177794404 0.1563913727341399 0.2502111993842982 15.24720002114212 0.04436527908729372 0.09575574109920304 4.698633019208858e-06 5.328028473673876 0.26955528112136706 T(ph)SPKPAVVETVTTAK ddPTM_PC-9_Lapatinib_30min_R1 1 TSPKPAVVETVTTAK 15 1 H0YI94;H0YIP0;P56192 H0YI94 MARS Methionine--tRNA ligase, cytoplasmic 1 T(0.517)S(0.483)PKPAVVETVTTAK 88.781 0.0034170999999999997 7326300.0 21181.0 62969.0 47189.0 48218.0 67374.0 50975.0 58498.0 74974.0 45266.0 44607.0 True False 20878.95505588031 62823.19914930381 43309.302574807705 51764.11257053272 63411.19378238047 48794.918078528804 61526.74020708769 78457.56574604333 40167.66640788818 52317.260514908645 0.3990834927209255 1.2008120939627818 0.8278205347251701 0.9894270468497047 1.2120511119711712 0.9326734159680228 1.1760313824068571 1.499649732685938 0.7677708276877716 1.0 15.674999378622648 -4.755006836126508 24.999831472946653 1.0767613137108039 0.3990823632647879 0.49204487695780463 0.20349661933358923 183.2572091534145 712155.9549963537 0.049702943571398324 0.4593350989611245 1.757895943117508e-05 4.755006836126508 -0.6776789504460159 T(ph)SPKPAVVETVTTAKPQQIQALMDEVTK ddPTM_PC-9_AZD4547_30min_R2 4 TSPKPAVVETVTTAKPQQIQALMDEVTK 28 2 H0YI94;H0YIP0;P56192 H0YI94 MARS Methionine--tRNA ligase, cytoplasmic 1 T(0.499)S(0.499)PKPAVVET(0.001)VTTAKPQQIQALMDEVTK;T(0.497)S(0.497)PKPAVVET(0.004)VT(0.002)T(0.001)AKPQQIQALMDEVTK;T(0.742)S(0.251)PKPAVVET(0.004)VT(0.001)T(0.001)AKPQQIQALMDEVTK;T(0.5)S(0.5)PKPAVVETVTTAKPQQIQALMDEVTK 69.152 8.722e-05 82417600.0 83312.0 80577.3 79612.6 120231.2 114843.0 99851.2 89321.6 87999.0 82841.0 91111.1 True False 109803.48300274884 106622.33645001714 78556.88490605135 92513.75439352302 98899.03178447689 93607.488679225 97271.0493611325 74400.77656584996 87219.8061367465 87921.3281210605 1.2488833523028495 1.2127016132332178 0.8934906533473302 1.052233358737929 1.1248582556476054 1.0646732787104298 1.10634190178745 0.8462198894835409 0.9920210260774488 1.0 16.423925559048556 -5.143185326371008 6.651178433058298 1.0158101254518672 1.238758910051979 0.5323620368282136 0.08283687922795199 0.19294533384802764 9.697130532362284 0.022414977313664097 0.06086842705568373 7.191420332248226e-06 5.143185326371008 0.2229487846001117 T(ph)SPKPAVVETVTTAKPQQIQALMDEVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSPKPAVVETVTTAKPQQIQALMDEVTK 28 2 H0YI94;H0YIP0;P56192 H0YI94 MARS Methionine--tRNA ligase, cytoplasmic 1 T(0.5)S(0.5)PKPAVVETVTTAKPQQIQALMDEVTK;T(0.499)S(0.499)PKPAVVET(0.001)VT(0.001)T(0.001)AKPQQIQALMDEVTK 73.574 2.3452e-05 51959100.0 208315.7 208491.2 161271.2 279989.3 257292.3 215133.8 246202.6 233582.1 210980.8 209143.1 True False 243579.4335873796 229188.828465661 165116.51703243173 264302.4072585579 206877.72080322975 203851.80480658964 222880.50737553538 227450.81737569236 214065.99506354076 247059.0884541315 0.985915697784994 0.9276680728473251 0.6683280427592403 1.0697943107955237 0.837361305336631 0.8251135632455648 0.9021344196245382 0.9206332735981111 0.8664566699527989 1.0 17.914496602986986 -10.800443886191447 3.2027752550432074 1.000546365434163 0.8870955601622654 0.09838571908563332 0.10037020579931967 33787231.059930265 50577964.34099493 182624.0749221047 0.02474820030031874 1.5832741233043136e-11 10.800443886191447 -0.11345080527189766 T(ph)SPKPAVVETVTTAKPQQIQALMDEVTK ddPTM_PC-9_Lapatinib_30min_R1 7 TSPKPAVVETVTTAKPQQIQALMDEVTK 28 2 H0YI94;H0YIP0;P56192 H0YI94 MARS Methionine--tRNA ligase, cytoplasmic 1 T(0.5)S(0.5)PKPAVVETVTTAKPQQIQALMDEVTK;T(0.5)S(0.5)PKPAVVETVTTAKPQQIQALMDEVTK;T(0.5)S(0.5)PKPAVVETVTTAKPQQIQALMDEVTK;T(0.496)S(0.496)PKPAVVET(0.006)VT(0.001)TAKPQQIQALMDEVTK;T(0.5)S(0.5)PKPAVVET(0.001)VTTAKPQQIQALMDEVTK;T(0.631)S(0.369)PKPAVVETVTTAKPQQIQALMDEVTK;T(0.5)S(0.5)PKPAVVETVTTAKPQQIQALMDEVTK 112.88 1.6982e-11 140491900.0 267961.8 214703.5 180956.4 207109.3 208725.2 209176.3 190101.2 194326.8 204415.6 163165.4 True False 264140.6155938238 214206.36723709424 166078.86330390387 222340.80881837182 196448.39410553226 200230.317262771 199943.7099636845 203355.93255286114 181392.16253630322 191368.32198577063 1.3802734582867076 1.1193407822900896 0.8678492949123148 1.1618475122277772 1.026546045171151 1.0463085801507905 1.0448109064704632 1.062641561794025 0.9478693268251096 1.0 17.54599250856365 -4.817811353929104 3.656204742195578 1.027308155728589 1.405550926478058 0.687017430445289 0.07310994732634946 0.133241813439223 3.0330956829302287 0.01752660125734948 0.12874921351823249 1.5212081589532034e-05 4.817811353929104 0.3782427707494689 T(ph)SPLKDNPSPEPQLDDIKR ddPTM_PC-9_AZD4547_30min_R2 1 TSPLKDNPSPEPQLDDIKR 19 2 Q96JC9-2;Q96JC9 Q96JC9-2 EAF1 ELL-associated factor 1 1 T(0.499)S(0.499)PLKDNPS(0.002)PEPQLDDIKR 48.354 0.034489 19850000.0 90041.0 58512.0 85832.0 110300.0 116600.0 100100.0 118180.0 100090.0 91280.0 127350.0 True False 118672.16503085365 77424.85973547633 84693.81159836757 84872.03911801237 100412.10266250416 93840.73117589395 128697.79105500407 84623.39033938962 96104.87444818654 122891.51526232308 0.9656660573965351 0.6300260808909871 0.6891754196177088 0.6906257029775026 0.817079213712724 0.7636062666782356 1.0472471657647557 0.6886023836450654 0.7820301852657767 1.0 16.907025786310683 -6.680100455747205 2.200282772099079 0.8534117467658792 0.7348711984468134 0.14290785095068048 0.1294496732400872 0.6262301374999258 6.211734349911619 0.04883506039930853 0.04745345637799684 2.0888129160288166e-07 6.680100455747205 -0.1185405483190658 T(ph)SPLKDNPSPEPQLDDIKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSPLKDNPSPEPQLDDIKR 19 2 Q96JC9-2;Q96JC9 Q96JC9-2 EAF1 ELL-associated factor 1 1 T(0.499)S(0.499)PLKDNPS(0.001)PEPQLDDIKR 97.12899999999999 0.0051563 11278000.0 16310.0 16030.0 13296.0 25103.0 26046.0 19758.0 22908.0 24135.0 20411.0 15725.0 True False 19070.9608628162 17621.352461420684 13613.0270653608 23696.56029502406 20942.47327277544 18721.855698028863 20737.988400442402 23501.4818231463 20709.47226118172 18575.818020968487 1.0266552375399454 0.9486178450676898 0.7328359402527705 1.2756671209997457 1.1274051699438195 1.007861709072275 1.1163970478733827 1.2651653777302134 1.1148619262852786 1.0 14.181138123492811 -5.766627512267161 24.99999980139125 1.1349543377960087 0.9072944935048847 0.4769130893742288 0.10877308078632504 108.73031097754503 523940.7928881666 0.030898295004107946 0.04741939455228267 1.711482598207639e-06 5.766627512267161 -0.22765984429112407 T(ph)SPLKDNPSPEPQLDDIKR ddPTM_PC-9_Lapatinib_30min_R1 1 TSPLKDNPSPEPQLDDIKR 19 2 Q96JC9-2;Q96JC9 Q96JC9-2 EAF1 ELL-associated factor 1 1 T(0.498)S(0.498)PLKDNPS(0.005)PEPQLDDIKR 45.577 0.043352 35264000.0 88011.0 75048.0 69915.0 82795.0 87174.0 83325.0 72073.0 75677.0 70241.0 73543.0 True False 86755.94700075907 74874.23096693531 64166.85857970458 88884.02049602343 82046.5967106781 79761.38399006205 75804.58728410264 79193.22969247107 62329.71890947893 86254.80956011207 1.0058099651857413 0.8680586201370546 0.7439220943962074 1.0304819052910785 0.9512118469579228 0.924718104379737 0.8788447585786328 0.9181311754828037 0.7226231120021261 1.0 16.39631728311101 -10.527169404826553 5.07323539889026 1.0000009282738658 0.8954933309541899 0.10246393912711393 0.09420752521772587 9.834232991484985e-07 1.928502441310309e-07 0.09068650620566411 0.021994513130736474 2.970507102902402e-11 10.527169404826553 -0.10450759731967585 T(ph)SPLNSSGSSQGR ddPTM_PC-9_AZD4547_30min_R2 1 TSPLNSSGSSQGR 13 0 G3XAH6;P51003;H0YJL4 G3XAH6 PAPOLA Poly(A) polymerase alpha 1 T(0.981)S(0.019)PLNSSGSSQGR 96.866 0.0077157 7498100.0 19856.0 19533.0 18596.0 15482.0 15531.0 17331.0 20116.0 21904.0 23725.0 23138.0 True False 26169.79496954315 25846.660261366214 18349.404889589445 11912.864094515584 13374.78873457422 16247.289830263917 21906.28503014437 18519.240103846412 24979.055064452532 22327.94566265909 1.1720646119857372 1.1575924024480124 0.8218133977402455 0.5335405359051224 0.5990156432950304 0.7276661308539295 0.9811151174010647 0.8294197945320917 1.11873503464437 1.0 14.446562898124306 -10.254586271018976 15.565989170453967 0.9998750270704998 0.8668546551359648 0.021923043478371707 0.2144342130350191 0.0 0.0 0.23058626582031513 0.05592538410552417 5.5643408967123556e-11 10.254586271018976 -0.13302037193453498 T(ph)SPLNSSGSSQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSPLNSSGSSQGR 13 0 G3XAH6;P51003;H0YJL4 G3XAH6 PAPOLA Poly(A) polymerase alpha 1 T(0.995)S(0.005)PLNSSGSSQGR;T(0.996)S(0.004)PLNSSGSSQGR 107.93 0.0023323 6520400.0 36958.0 66022.0 51787.0 40814.0 48476.0 30491.0 41810.0 28573.0 27068.0 30650.0 True False 43214.25944622693 72576.22783580267 53021.79848329115 38527.32390077331 38977.4757878777 28891.998283662208 37849.45412181323 27822.989025595987 27463.81829237505 36206.60237473351 1.1935463868983094 2.0045025789674593 1.4644234754347454 1.0640966391162758 1.0765295065376757 0.7979759598714586 1.045374369295313 0.7684507023783054 0.7585306681949383 1.0 15.143965180304304 -5.809334929214694 2.323616476851977 0.9013774053356796 1.6294623664937058 0.6553716518005193 0.21078639545901579 0.16323893743790371 1.7978452346374956 0.061276292008288546 0.10986521159174209 1.5511902659381214e-06 5.809334929214694 0.7280849611580262 T(ph)SPLNSSGSSQGR ddPTM_PC-9_Lapatinib_30min_R1 2 TSPLNSSGSSQGR 13 0 G3XAH6;P51003;H0YJL4 G3XAH6 PAPOLA Poly(A) polymerase alpha 1 T(0.994)S(0.006)PLNSSGSSQGR;T(0.861)S(0.138)PLNSSGSSQGR 93.228 0.010332 16137200.0 23139.6 39260.0 34563.0 39668.0 44162.0 33027.0 56429.0 53502.0 40025.0 35891.0 True False 22809.62506071707 39169.0958821272 31721.36355703827 42585.31704856884 41564.47798583259 31614.512199697303 59350.617510782446 55987.89823865364 35516.96301806488 42094.711528248605 0.5418643870598842 0.9304992114233137 0.7535712303373533 1.0116548018149738 0.9874037967439168 0.7510328744854724 1.4099304961611123 1.3300458942706306 0.8437393137670138 1.0 15.361351374569947 -4.255916493999018 0.4278855276592647 1.1246389758767104 2.6944052552394465e-09 0.36128020214857315 0.19895618825819295 9.237809742816525 0.9406779899321828 0.15010425014905987 5.791448258180095 5.5473236646197825e-05 4.255916493999018 -1.124638973182305 T(ph)SPLVSQNNEQGSTLR ddPTM_PC-9_AZD4547_30min_R2 4 TSPLVSQNNEQGSTLR 16 0 A0A1W2PNZ9;Q15652-3;Q15652;H7BXU7 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 T(0.613)S(0.387)PLVSQNNEQGSTLR;T(0.873)S(0.127)PLVSQNNEQGSTLR;T(0.614)S(0.386)PLVSQNNEQGSTLR;T(0.997)S(0.003)PLVSQNNEQGSTLR 194.55 2.2749000000000003e-11 40993300.0 62293.3 77564.0 81485.0 71901.0 72668.4 85831.0 77874.0 88531.0 80006.0 72354.0 True False 82101.27361886781 102635.04615331022 80404.45565864693 55325.33530937641 62579.64700788957 80463.97400157999 84804.63513807248 74850.56818999404 84234.95382451375 69820.9084828437 1.1758837775512707 1.4699758050058824 1.1515813444106617 0.7923892213887602 0.8962880656768675 1.1524337873855006 1.214602287206139 1.0720365835455465 1.2064431078723625 1.0 16.09137150835599 -5.514223079686704 24.993447942505764 1.0493042492113962 1.3198920305126822 0.37585535342114496 0.1408127239125201 422.4542735149481 1219845.0669499927 0.04042599907989812 0.0748648454334892 3.0603910295473712e-06 5.514223079686704 0.270587781301286 T(ph)SPLVSQNNEQGSTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSPLVSQNNEQGSTLR 16 0 A0A1W2PNZ9;Q15652-3;Q15652;H7BXU7 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 T(0.5)S(0.5)PLVSQNNEQGSTLR;T(0.997)S(0.003)PLVSQNNEQGSTLR;T(0.984)S(0.016)PLVSQNNEQGSTLR 223.14 3.9085e-28 31940600.0 45475.0 58691.0 57364.0 50090.0 50300.0 34615.5 45924.0 33879.0 37099.1 33983.7 True False 53173.019327809096 64517.45460469379 58731.77531418145 47283.61969397109 40444.07608157125 32800.20224289492 41573.746259032545 32989.71214776769 37641.604152898304 40144.675795178824 1.32453478013129 1.6071235681131597 1.463002855318484 1.1778304035936347 1.0074580322411866 0.8170498725719952 1.0355980073458544 0.8217705460142137 0.9376487269432345 1.0 15.292921041931363 -6.00806488497273 2.026356875560436 0.9205900114742562 1.487751636654008 0.8662077101103551 0.0931311063808167 0.10085407476689354 0.8304899915167172 0.02880335194604505 0.04538002651736108 9.8160127772061e-07 6.00806488497273 0.5671616251797518 T(ph)SPLVSQNNEQGSTLR ddPTM_PC-9_Lapatinib_30min_R1 2 TSPLVSQNNEQGSTLR 16 0 A0A1W2PNZ9;Q15652-3;Q15652;H7BXU7 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 T(0.5)S(0.5)PLVSQNNEQGSTLR;T(0.6)S(0.4)PLVSQNNEQGSTLR 149.59 4.7701e-05 27885000.0 27983.0 32971.0 34923.0 29143.0 39758.0 34229.0 33163.0 36163.0 32150.0 31806.0 True False 27583.957288546277 32894.657675232214 32051.76574667843 31286.273438198088 37419.51260723544 32765.105461696166 34880.01787219476 37843.26499952208 28528.92844549122 37303.624721169006 0.7394444238254674 0.8818086156803203 0.8592131726140205 0.8386925847568856 1.0031066119427443 0.8783357034766295 0.935030258665483 1.0144661619986446 0.7647763095070401 1.0 15.187028200731923 -3.403896447152524 0.5905918850468216 0.9282980819831114 2.4352770006256337e-13 0.3341454818147681 0.07501953257556412 19.335118160467477 1.437627346970181 0.03367934555041887 17.591290817599557 0.0003945513673897411 3.403896447152524 -0.9282980819828678 T(ph)SPPCS(ph)PANLSR ddPTM_PC-9_Lapatinib_30min_R1 2 TSPPCSPANLSR 12 0 P49585;C9JEJ2 P49585 PCYT1A Choline-phosphate cytidylyltransferase A 2 T(0.792)S(0.208)PPCS(1)PANLSR;T(0.788)S(0.212)PPCS(1)PANLSR 171.11 0.0056506 146745000.0 181072.0 372890.0 403350.0 387340.0 394790.0 422470.0 346710.0 407350.0 422040.0 331990.0 True False 178489.88007546176 372026.596115293 370188.1199760254 415826.2757283623 371569.2283870037 404401.9429256702 364660.94733494084 426276.9681042866 374505.4109217765 389374.02915113064 0.45840211907451883 0.9554478939603225 0.9507262741253386 1.0679353130841824 0.9542732708626126 1.0385950593759468 0.9365312528160482 1.094775039397485 0.9618140473781237 1.0 18.570797135422644 -4.750660412598402 3.9155200544392117 1.0015506915101602 0.3879995866031828 0.9120826356451872 0.050195970886651245 0.06877470033418485 1.8744733045390711 0.011807548014603939 0.12637944069541457 1.7755773134217415e-05 4.750660412598402 -0.6135511049069774 down T(ph)SPPCSPANLSR ddPTM_PC-9_AZD4547_30min_R2 2 TSPPCSPANLSR 12 0 P49585;C9JEJ2 P49585 PCYT1A Choline-phosphate cytidylyltransferase A 1 T(0.996)S(0.004)PPCSPANLSR;T(0.999)S(0.001)PPCSPANLSR 138.63 0.00017111 34747000.0 35739.0 41247.0 49435.0 53120.0 49816.0 48832.0 48403.0 50328.0 44384.0 43252.0 True False 47103.258582619994 54579.28612095286 48779.45959974479 40874.00469581887 42899.90828675228 45778.527320492045 52710.77323096433 42550.96402238775 46730.04762826814 41737.76064488423 1.1285526069159968 1.3076716449961867 1.1687129075939933 0.979305167893064 1.0278440343686839 1.0968132121411045 1.2629037211517256 1.019483636997741 1.1196108010168442 1.0 15.349065577239644 -5.531598794548915 24.489164251285246 1.0797286078412804 1.2231321745469512 0.3284348818252524 0.0861921084131023 163.2139423103862 458364.3003587386 0.02371821113156304 0.041169536086357636 2.940364735095431e-06 5.531598794548915 0.14340356670567078 T(ph)SPPCSPANLSR ddPTM_PC-9_Lapatinib_30min_R1 1 TSPPCSPANLSR 12 0 P49585;C9JEJ2 P49585 PCYT1A Choline-phosphate cytidylyltransferase A 1 T(0.997)S(0.003)PPCSPANLSR 113.07 0.0021469 19924000.0 16193.0 19583.0 17868.0 15618.0 21124.0 18826.0 19109.0 17375.0 17114.0 14014.0 True False 15962.08485056748 19537.65676667593 16398.962012474603 16766.599820120697 19881.527851381896 18020.85586554944 20098.370518944914 18182.30593055598 15186.44110159057 16436.30122751878 0.9711482303477541 1.1886893831055279 0.9977282470960279 1.0200956765168618 1.2096108227862654 1.0964057920390078 1.2228037342911948 1.106228565591991 0.9239573363479364 1.0 14.004598055631591 -8.251614633951197 23.647400218226938 0.9619786710541662 1.1057821782699009 0.3028285751995734 0.08454083554590827 345.6405720319468 831940.3897942245 0.05847720461393718 0.021426317965057822 5.602545161855643e-09 8.251614633951197 0.14380350721573465 T(ph)SPPLLDR ddPTM_PC-9_AZD4547_30min_R2 10 TSPPLLDR 8 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(0.941)S(0.059)PPLLDR;T(0.883)S(0.117)PPLLDR;T(0.995)S(0.005)PPLLDR;T(0.936)S(0.064)PPLLDR;T(0.5)S(0.5)PPLLDR;T(0.99)S(0.01)PPLLDR;T(0.989)S(0.011)PPLLDR;T(0.988)S(0.012)PPLLDR;T(0.923)S(0.077)PPLLDR;T(0.607)S(0.393)PPLLDR 174.86 0.00012308 4741965800.0 521311.4 577475.0 603330.6 710949.0 647294.0 674731.0 612883.0 689946.0 600118.0 623795.0 True False 687077.5812492704 764132.5006108875 595330.0420347883 547050.692102555 557428.4012077457 632539.9639065142 667428.3996883064 583330.6990818311 631839.0123148205 601956.1269184201 1.1414080703299931 1.2694156042944411 0.9889924122584273 0.9087883113725559 0.9260282872464075 1.0508074187144856 1.1087658549221135 0.9690584961200783 1.0496429624354506 1.0 19.199298815601544 -5.270808845037261 24.85714341078939 0.9989178352325417 1.2054118379837597 0.6275770486302588 0.06320807610411107 356.69760496023423 946318.4331758101 0.017718426675288397 0.03770109476683168 5.360325406245277e-06 5.270808845037261 0.206494002751218 T(ph)SPPLLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 13 TSPPLLDR 8 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(0.995)S(0.005)PPLLDR;T(0.936)S(0.064)PPLLDR;T(0.783)S(0.217)PPLLDR;T(0.992)S(0.008)PPLLDR;T(0.645)S(0.355)PPLLDR;T(0.928)S(0.072)PPLLDR;T(0.983)S(0.017)PPLLDR;T(0.713)S(0.287)PPLLDR;T(0.879)S(0.121)PPLLDR;T(0.979)S(0.021)PPLLDR;T(0.5)S(0.5)PPLLDR;T(0.999)S(0.001)PPLLDR;T(0.917)S(0.083)PPLLDR 162.64 5.3315e-05 4238487200.0 712138.0 810663.0 766621.0 818494.0 880926.0 707080.0 858760.0 712881.0 676861.0 587827.0 True False 832688.8980333678 891140.2651548786 784900.1520663336 772636.4347733506 708314.8740802018 669999.4800567991 777412.0359160088 694168.6291098557 686758.8116297944 694395.3818640275 1.1991567337301505 1.2833326494233175 1.1303360773502786 1.1126750766966418 1.020045485007128 0.9648674192766947 1.1195524282277516 0.9996734529634068 0.9890025618924286 1.0 19.40539782748415 -5.734725151051562 1.4608232202868363 1.01799049695595 1.24358964694918 0.7734646400507579 0.047274915840458696 0.1928228083500051 0.8242551481027146 0.015446128209553244 0.03719711492661782 1.8419373268353602e-06 5.734725151051562 0.22559914999323016 T(ph)SPPLLDR ddPTM_PC-9_Lapatinib_30min_R1 8 TSPPLLDR 8 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(0.944)S(0.056)PPLLDR;T(0.937)S(0.063)PPLLDR;T(0.939)S(0.061)PPLLDR;T(0.988)S(0.012)PPLLDR;T(0.988)S(0.012)PPLLDR;T(0.984)S(0.016)PPLLDR;T(0.983)S(0.017)PPLLDR;T(0.924)S(0.076)PPLLDR 182.39 0.0010914000000000002 4428973800.0 447872.1 696361.0 610346.2 593459.0 669771.0 609883.0 581984.2 625876.0 620484.6 534421.0 True False 441485.3617243161 694748.6188887921 560165.8914404653 637103.9545811883 630376.38660045 583799.7257967117 612116.4942054389 654956.4838326722 550599.0903554965 626794.9577787778 0.7043537224499096 1.1084144986597004 0.8936987837706432 1.0164471597521194 1.005713876248086 0.9314046300971667 0.9765817140180002 1.044929407463156 0.8784357364754456 1.0 19.257634048604658 -4.744449160401935 24.997971383351732 0.9823641479403705 0.7043528994733957 0.6199803475170715 0.06566124167319057 651.4286435190292 958405.9244793052 0.015001923930017662 0.4274555855006025 1.8011539696889573e-05 4.744449160401935 -0.2780112484669748 T(ph)SPQELSEELSR ddPTM_PC-9_AZD4547_30min_R2 2 TSPQELSEELSR 12 0 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5;Q96PU5-3;K7ERN1 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 T(0.984)S(0.016)PQELSEELSR;T(0.7)S(0.3)PQELSEELSR 151.7 0.00040551 22477000.0 13259.900000000001 12527.099999999999 14607.9 16381.3 14827.2 15497.2 14861.5 18612.4 16639.9 15274.1 True False 17476.27237694628 16576.240094207787 14414.189701367704 12604.844373562075 12768.69921610192 14528.15763415648 16184.144709459659 15736.281250403152 17519.45114297087 14739.358408074213 1.1856874562038457 1.124624263504396 0.97793874755577 0.8551827036553469 0.8662995269256247 0.9856709655827327 1.0980223332240835 1.0676367868076826 1.188616943690963 1.0 13.847386106042467 -9.61738170107807 11.247105859715894 1.0000020382478618 1.0301298384643376 0.0053015179457365225 0.11243178627564587 0.0 0.0 0.12172642197187554 0.029522993836385257 2.4133388204749e-10 9.61738170107807 0.030127800216475764 T(ph)SPQELSEELSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSPQELSEELSR 12 0 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5;Q96PU5-3;K7ERN1 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 T(0.827)S(0.173)PQELSEELSR;T(0.986)S(0.014)PQELSEELSR 126.32 0.00065302 20408000.0 15459.199999999999 17742.9 16969.800000000003 17620.5 18353.300000000003 14191.0 16975.199999999997 15355.3 16255.0 12219.6 True False 18076.13722688217 19504.29785325895 17374.42439032489 16633.280511431767 14757.102615266442 13446.79897817227 15367.186166194771 14952.239645285192 16492.698623561268 14434.916749699625 1.2522508816864713 1.3511888008404909 1.203638697167161 1.1522948694371853 1.0223198977280918 0.9315466941263851 1.0645843292802188 1.0358383012909536 1.1425558532510736 1.0 13.817275166711717 -5.832730743191923 1.8256527765205708 1.0320139689296675 1.2978290906017564 0.7749825692460128 0.05788439650514623 0.15844974393378458 1.0781068972113246 0.018775477362684635 0.03582683864169798 1.4698372747914799e-06 5.832730743191923 0.265815121672089 T(ph)SPQELSEELSR ddPTM_PC-9_Lapatinib_30min_R1 1 TSPQELSEELSR 12 0 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5;Q96PU5-3;K7ERN1 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 T(0.885)S(0.115)PQELSEELSR 109.6 0.0031615 10279000.0 6687.0 6535.7 9420.1 6873.1 6052.2 6601.9 4735.6 5650.6 6195.7 4651.3 True False 6591.64215375439 6520.566988202211 8645.615740637564 7378.57070198947 5696.221495083009 6319.552126780563 4980.78619653124 5913.147504529482 5497.87502238662 5455.2710075323275 1.2083070015500652 1.19527828758626 1.5848187429552427 1.3525580474006809 1.044168380859171 1.1584304644177872 0.913022687535423 1.0839328598643303 1.007809697225943 1.0 12.413435153348672 -6.263300952295908 22.670617598627665 1.0388738744717398 1.3430702664365568 0.6192313863933593 0.11541349882008108 31.74248091889353 386568.24774540245 0.03671172604600653 0.04383064807287487 5.453797992178598e-07 6.263300952295908 0.30419639196481696 T(ph)SPQELSEELSRR ddPTM_PC-9_AZD4547_30min_R2 1 TSPQELSEELSRR 13 1 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5;Q96PU5-3;K7ERN1 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 T(0.878)S(0.109)PQELSEELS(0.013)RR 92.8 0.0037676000000000003 2832500.0 9802.9 8767.3 11785.0 14351.0 17545.0 13505.0 11497.0 13099.0 11930.0 11488.0 True False 12920.018287013223 11601.158271104085 11628.723199817789 11042.598670739768 15109.179598744757 12660.530215089382 12520.21072735981 11074.850535075062 12560.595444422295 11085.80861667506 1.1654556499901307 1.0464873309876417 1.0489738369040655 0.9961022287656764 1.3629298611576082 1.1420484199993906 1.1293908419569096 0.9990115216689277 1.1330337622398505 1.0 13.436426386084817 -8.54496904909909 0.9376121310954739 1.008103491652319 1.120916717971839 0.10106853197914012 0.10102949274866564 1.624329692524505 3.144180644234335 0.10124911176213697 0.03453824311860018 2.8512214584998905e-09 8.54496904909909 0.11281322631951984 T(ph)SPQELSEELSRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSPQELSEELSRR 13 1 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5;Q96PU5-3;K7ERN1 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 T(0.779)S(0.216)PQELSEELS(0.005)RR 70.167 0.024477000000000002 1839100.0 10160.0 13524.0 11042.0 14280.0 17711.0 15339.0 14079.0 14914.0 13282.0 12860.0 True False 11879.887330853013 14866.573342997708 11305.28315701819 13479.937896384652 14240.6566894773 14534.595837233768 12745.335196866972 14522.52330268919 13476.224122924685 15191.416200296006 0.7820131562600157 0.978616683723538 0.7441888898283167 0.8873391208992085 0.9374146887766672 0.9567637174571362 0.8389826879088882 0.9559690229806367 0.8870946556425793 1.0 13.890968749054107 -1.5230618553328557 0.0235636784176712 1.5671804809416052 1.3752625763267497e-08 0.2673233180313911 0.06958270886981055 3179.0148747812605 5.785854094533755 135.31476219171003 271.14979387867004 0.02998735387183941 1.5230618553328557 -1.5671804671889795 T(ph)SPQELSEELSRR ddPTM_PC-9_Lapatinib_30min_R1 2 TSPQELSEELSRR 13 1 A0A1B0GVY1;Q96PU5-4;Q96PU5-7;Q96PU5;Q96PU5-9;Q96PU5-2;Q96PU5-6;Q96PU5-5;Q96PU5-3;K7ERN1 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 T(0.959)S(0.041)PQELSEELSRR;T(0.989)S(0.01)PQELSEELS(0.001)RR 141.55 6.5938e-05 4903800.0 26623.0 18648.2 24255.0 20035.0 19325.5 21138.3 15113.900000000001 15279.4 19407.5 15587.8 True False 26243.351137939735 18605.02123864199 22260.84752700757 21508.44073480075 18188.81208539486 20234.264184784017 15896.423789119335 15989.336704192074 17221.622979964875 18282.13046056208 1.4354646026923106 1.0176615509213462 1.217628742723848 1.176473430227315 0.9948956509544375 1.1067782405575242 0.8695060908470622 0.8745882619470425 0.9419921281666317 1.0 14.158146580459299 -6.212004308445215 0.6404574480201236 0.9084127141749617 1.2770870381533623 0.575762652320654 0.10814412854737039 0.6839733198832563 0.5834491226105656 0.07024883448103189 0.1432048893289277 6.137559163311398e-07 6.212004308445215 0.3686743239784006 T(ph)SPQVLGSILK ddPTM_PC-9_AZD4547_30min_R2 2 TSPQVLGSILK 11 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 T(0.998)S(0.002)PQVLGSILK;T(0.976)S(0.024)PQVLGSILK 136.33 0.00019662 217820000.0 583960.0 496890.0 633390.0 810350.0 759900.0 675070.0 636340.0 716570.0 585360.0 643270.0 True False 769647.1328774394 657499.975286451 624990.8347503261 623536.3272826958 654401.0018287922 632857.7661829257 692973.0272460774 605840.5716404858 616300.9345638745 620749.3130961508 1.2398678768384317 1.0592037097987217 1.0068329059165924 1.0044897579872365 1.0542113990667097 1.0195061884585597 1.1163492453816692 0.9759826694268839 0.992833856697982 1.0 19.24365123439378 -4.764123286390398 3.381877547724073 1.0245374306957251 1.2726512792356237 0.7518056875251954 0.03747081445761189 0.16519588374187721 2.9394324458030776 0.009650877881020913 0.10987191638477803 1.7213798447767195e-05 4.764123286390398 0.2481138485398986 T(ph)SPQVLGSILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSPQVLGSILK 11 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 T(0.989)S(0.011)PQVLGSILK;T(0.977)S(0.023)PQVLGSILK;T(0.997)S(0.003)PQVLGSILK 159.5 0.00074206 112876700.0 193316.0 210577.0 196674.0 217947.0 235699.0 210236.0 228745.0 214951.0 216096.0 169157.0 True False 226040.5806349584 231481.69290508903 201363.45405029837 205736.13618370757 189515.47292942906 199210.85406067394 207076.617629614 209308.76400941054 219255.9951865328 199823.82505392496 1.1311993480955462 1.1584288952662216 1.0077049320618197 1.0295876186345 0.9484127975144402 0.9969324429002118 1.0362959350504464 1.0474665068238282 1.0972465126586572 1.0 17.608369080780136 -5.261908404195321 24.99997202867195 1.0196298384683173 1.1448141308150448 0.6442328195596749 0.036961389307961515 25.7924833662198 1374872.3786369115 0.010354095223424712 0.02397270916133499 5.471313446301838e-06 5.261908404195321 0.12518429234672745 T(ph)SPQVLGSILK ddPTM_PC-9_Lapatinib_30min_R1 1 TSPQVLGSILK 11 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 T(0.981)S(0.019)PQVLGSILK 164.92 0.0042354 95503000.0 276870.0 214310.0 240980.0 242810.0 256100.0 239470.0 225890.0 220660.0 253380.0 175890.0 True False 272921.7830282602 213813.77836216765 221167.55460970098 260667.05739041514 241036.70151197218 229228.42633183487 237585.47891174152 230912.6691589346 224841.67619031318 206292.3521413074 1.3229854630835398 1.0364600342319437 1.0721073869873967 1.263580809878312 1.1684228669168761 1.1111823775939913 1.1516931017830403 1.119346726924528 1.0899176525763774 1.0 17.654330811742987 -8.691549531392546 0.6736039072417253 0.9980170492482453 1.1610585018878543 0.2921590970961282 0.07891602011644208 1.3571725109910198 1.3271957591797416 0.08134545902048478 0.031380427959980445 2.034466151253129e-09 8.691549531392546 0.163041452639609 T(ph)SPSGGTWSSVVSGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSPSGGTWSSVVSGAK 16 0 F8WB06;F8VRK6 F8WB06 ATXN2 1 T(0.903)S(0.095)PS(0.002)GGTWSSVVSGAK;T(0.98)S(0.02)PSGGTWSSVVSGAK 189.33 7.965e-08 11593500.0 43826.0 42665.0 39499.0 49738.0 58269.0 47172.0 45232.0 47804.0 41811.0 36769.0 True False 51244.8761970437 46900.49923683799 40440.805960791695 46951.34111277168 46851.60773751638 44698.21727843998 40947.29750867867 46549.19565252478 42422.4067763593 43434.92863675616 1.179807997973283 1.079787643466948 0.931066476452531 1.0809581732117735 1.0786620171368007 1.0290846256994832 0.9427274038163753 1.071699600149296 0.976688764269316 1.0 15.406568046740741 -4.895715719165976 3.7567823640773383 1.0183407267875724 1.179978879604158 0.49679129126432886 0.05128878771683659 0.20044100797133557 4.8934738377162805 0.012917950661513657 0.07274407347334054 1.271406070901e-05 4.895715719165976 0.16163815281658556 T(ph)SPSGGTWSSVVSGAK ddPTM_PC-9_Lapatinib_30min_R1 1 TSPSGGTWSSVVSGAK 16 0 F8WB06;F8VRK6 F8WB06 ATXN2 1 T(0.898)S(0.101)PS(0.001)GGTWSSVVSGAK 172.26 4.7848999999999995e-05 5888400.0 34520.0 27851.0 31688.0 30296.0 34400.0 30354.0 23421.0 27975.0 31102.0 22500.0 True False 34027.7384698073 27786.512720660343 29082.734959217305 32524.06890449332 32376.659633002168 29055.830178629996 24633.624780166865 29274.82062775849 27598.965241420454 26389.09502063452 1.2894621222592086 1.0529543623581308 1.1020739792886622 1.2324814048781005 1.2268954129607617 1.1010544376724654 0.9334774368315779 1.1093529582908215 1.0458473555019563 1.0 14.687654255729754 -7.000662514649825 12.628076482160434 1.029272920718761 1.1713691390487675 0.4956296287005113 0.07503927917257518 0.08450212188584781 878.5068858675788 0.027496254122024225 0.023471223176423674 9.984756666215413e-08 7.000662514649825 0.14209621833000652 T(ph)SPSGGTWSSVVSGVPR ddPTM_PC-9_AZD4547_30min_R2 2 TSPSGGTWSSVVSGVPR 17 0 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4 Q99700 ATXN2 Ataxin-2 1 T(0.499)S(0.499)PS(0.002)GGTWSSVVSGVPR;T(0.981)S(0.019)PSGGTWSSVVSGVPR 189.52 3.6442e-08 84807000.0 201135.0 198340.0 266200.0 309310.0 290510.0 251870.0 246770.0 268660.0 245990.0 263440.0 True False 265091.74613210466 262449.5262499038 262670.01406800986 238003.35829186227 250177.70106761713 236120.52908364078 268732.05194316653 227144.77019263082 258992.52920146196 254217.04578489592 1.0427772272847915 1.0323836682138683 1.0332509893544526 0.9362210844557105 0.9841106456696981 0.9288146998743452 1.0570969036063473 0.8935072370592642 1.018785063770298 1.0 17.95570124374448 -5.713049751773194 12.328366314782356 0.9716378118851691 1.0358250418513804 0.28952445880112976 0.04443576347906313 1.0772771720521 271.810705896272 0.0111393298901419 0.019282150213086168 1.9362001446228207e-06 5.713049751773194 0.06418722996621129 T(ph)SPSGGTWSSVVSGVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSPSGGTWSSVVSGVPR 17 0 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4 Q99700 ATXN2 Ataxin-2 1 T(0.829)S(0.171)PSGGTWSSVVSGVPR 139.0 0.00018372 6372500.0 21199.0 19526.0 21941.0 20908.0 26838.0 23050.0 23315.0 23152.0 19492.0 16950.0 True False 24787.57200066466 21464.412237161592 22464.15665170586 19736.592544650586 21579.286558195017 21841.217422794063 21106.434414017585 22544.2845315717 19777.033624758922 20022.900823873835 1.237961083596328 1.0719931355585104 1.1219231843230852 0.9857009590297787 1.0777302823407817 1.0908118466407326 1.0541147159282647 1.1259249960770694 0.9877207003481854 1.0 14.289363379749867 T(ph)SPSGGTWSSVVSGVPR ddPTM_PC-9_Lapatinib_30min_R1 1 TSPSGGTWSSVVSGVPR 17 0 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4 Q99700 ATXN2 Ataxin-2 1 T(0.98)S(0.02)PSGGTWSSVVSGVPR 198.61 5.6746e-12 34999000.0 140290.0 133460.0 166630.0 117680.0 173430.0 140070.0 143950.0 131260.0 126040.0 102780.0 True False 138289.43887396454 133150.9815697579 152930.32461040124 126334.57976897195 163229.18837649887 134079.53261911767 151403.02664724068 137358.8187881886 111844.04793996002 120545.38605425827 1.1471981085341545 1.1045713645964497 1.2686534890814178 1.0480250128537307 1.3540890590621888 1.1122742811472486 1.2559835892772635 1.1394780280214334 0.9278169127901609 1.0 16.879216906430507 -8.164907978615664 4.633958198763777 0.9652871035687384 1.1837257380170563 0.49780269488960427 0.0870293727922806 0.16653624327859837 5.770016967862891 0.05964171131649988 0.020849350700954207 6.840565746685887e-09 8.164907978615664 0.2184386344483179 T(ph)SPSKSPFLHSGMK ddPTM_PC-9_AZD4547_30min_R2 1 TSPSKSPFLHSGMK 14 1 O14497-2;O14497;H0Y488;A0A1B0GTU5;O14497-3;H0YEW5 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 T(0.457)S(0.457)PS(0.086)KS(0.001)PFLHSGMK 65.949 0.02355 12419000.0 33419.0 26386.0 68347.0 86605.0 84432.0 76578.0 58396.0 83107.0 64416.0 82805.0 True False 44045.546841617754 34914.75849364714 67440.67412286348 66639.55528391183 72710.07420240638 71789.56555432173 63593.130871958216 70264.72275887337 67820.89825212958 79906.02215388027 0.5512168626889767 0.43694777380370026 0.8439998926862927 0.8339741297042627 0.9099448607563497 0.8984249699737505 0.7958490381299766 0.8793420178464143 0.8487582840943131 1.0 16.28601661617126 -5.284892543979148 8.652984803387403 0.8698663855725274 0.4939937647125355 0.8733530095076432 0.05817821735502894 0.07558980593660702 26.324200322381174 0.014336300969055565 0.030853825936412393 5.1892841975691636e-06 5.284892543979148 -0.3758726208599919 T(ph)SPTPGDFPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSPTPGDFPK 10 0 Q9UPU7;C9JW56;Q9UPU7-2 Q9UPU7 TBC1D2B TBC1 domain family member 2B 1 T(0.5)S(0.5)PT(0.001)PGDFPK 89.171 0.023275999999999998 4429600.0 38981.0 42468.0 38232.0 43275.0 44156.0 40144.0 52032.0 37912.0 37772.0 32409.0 True False 45579.71339015559 46683.94237876566 39143.59587566744 40850.44204944297 35503.94877649821 38038.777970526906 47103.15228094197 36916.85017108439 38324.34404239657 38284.49515049718 1.1905528128549363 1.219395533237413 1.0224399126015142 1.0670231353151973 0.9273714760226409 0.9935818095810234 1.230345394285035 0.9642767921050924 1.001040862410298 1.0 15.224472612471391 -5.263070191009 24.96156029251768 1.028601308711687 1.2049741856208405 0.46177866556888403 0.07734334478058254 119.72617919208653 1832591.9846018872 0.020648292720264052 0.04698888859782961 5.456696624125515e-06 5.263070191009 0.1763728769091535 T(ph)SPTPPESATTVK ddPTM_PC-9_AZD4547_30min_R2 2 TSPTPPESATTVK 13 0 Q5M775;Q5M775-4;J3KSG2 Q5M775 SPECC1 Cytospin-B 1 T(0.864)S(0.136)PTPPESATTVK;T(0.999)S(0.001)PTPPESATTVK 226.42 3.8486e-19 342090000.0 151272.0 158238.0 196643.0 255890.0 210918.0 190440.0 202533.0 226555.0 188941.0 207471.0 True False 199373.3493469347 209385.33898725605 194035.38533574645 196898.51396108995 181635.6764096922 178531.75669467816 220558.04464159044 191546.1304659844 198928.03552930366 200207.5034392576 0.9958335522995222 1.0458416162748017 0.9691713946905904 0.983472200485375 0.9072371079478546 0.8917335945345535 1.1016472452467654 0.9567380201816411 0.9936092909207964 1.0 17.611136519398677 -10.470001638291045 14.991427494265842 0.99999948347432 0.9821086531489267 0.0078027920199452705 0.057670012615676614 0.0 0.0 0.05737835701901975 0.013916295683165821 3.388428779182657e-11 10.470001638291045 -0.017890830325393292 T(ph)SPTPPESATTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSPTPPESATTVK 13 0 Q5M775;Q5M775-4;J3KSG2 Q5M775 SPECC1 Cytospin-B 1 T(0.999)S(0.001)PTPPESATTVK;T(0.991)S(0.009)PTPPESATTVK;T(0.983)S(0.017)PTPPESATTVK 231.52 7.5145e-20 236723200.0 221723.0 219532.0 239185.0 302864.0 315867.0 257674.0 260837.0 264874.0 237671.0 195360.0 True False 259256.32467113377 241325.6861235555 244888.07751416415 285895.51197833574 253975.1288202319 244161.12183084787 236128.63106365493 257921.33815720104 241146.48874564335 230777.22153109056 1.1234051738343096 1.0457084305048878 1.0611449253503233 1.238837655127153 1.1005207842231348 1.057994893130968 1.0231886383632685 1.117620432580057 1.0449319354213467 1.0 17.81614130671356 -6.720013640908344 4.9449107017609855 1.0542487116744426 1.1149550259786891 0.25367778926419193 0.05585691320228255 0.336870587144935 18.710526848016382 0.019953817232705486 0.019394652831767088 1.9054008696163426e-07 6.720013640908344 0.060706314304246556 T(ph)SPTPPESATTVK ddPTM_PC-9_Lapatinib_30min_R1 4 TSPTPPESATTVK 13 0 Q5M775;Q5M775-4;J3KSG2 Q5M775 SPECC1 Cytospin-B 1 T(0.893)S(0.107)PTPPESATTVK;T(0.999)S(0.001)PTPPESATTVK;T(0.997)S(0.003)PTPPESATTVK;T(0.966)S(0.034)PTPPESATTVK 231.74 6.1632e-20 357670700.0 346247.0 279836.0 329821.0 286847.0 299847.0 272698.0 262029.0 269380.0 324355.0 233654.0 True False 341309.45428607665 279188.0569350731 302704.39052587835 307942.68527354096 282210.58898188366 261035.34223008595 275595.57950225595 281896.37822003925 287822.72429042944 274040.7825756149 1.2454695650706682 1.018782877172809 1.104596139599603 1.1237111585337545 1.0298123743826868 0.9525419529775995 1.0056735968713417 1.0286657904367091 1.0502915718794947 1.0 18.06403108456184 -6.339165727998027 4.492746764096535 1.0076694976569494 1.1144473005733375 0.48430478020229606 0.056575785372613194 0.2103800514338161 7.892847674397505 0.01758851245282425 0.020239224414420335 4.5796709183286563e-07 6.339165727998027 0.10677780291638816 T(ph)SPTVATQTGASATSTR ddPTM_PC-9_AZD4547_30min_R2 3 TSPTVATQTGASATSTR 17 0 Q6P1L5;Q6P1L5-2 Q6P1L5 FAM117B Protein FAM117B 1 T(0.498)S(0.498)PT(0.004)VATQTGASATSTR;T(0.897)S(0.103)PTVATQTGASATSTR;T(0.987)S(0.013)PTVATQTGASATSTR 183.23 1.0081e-07 53910400.0 57727.0 56236.0 76178.0 102267.0 94980.0 84226.0 65998.0 88956.0 65994.0 81601.0 True False 76082.98520380826 74413.18724508224 75167.82994617896 78690.9231593997 81793.66647413929 78959.33490530319 71871.69414493292 75209.89420552248 69482.30811057874 78744.17382741118 0.9662046283013188 0.9449992758598058 0.9545827493336747 0.9993237510100975 1.0387265812631659 1.002732406315718 0.9127239597745843 0.955116938179642 0.8823803048955433 1.0 16.264885563985935 -9.907777560800003 5.832579089078202 0.9999999972929776 0.9640758074127207 0.06511646713917241 0.04261394262872607 9430627.753662886 2669961.0728386156 0.04458894413311884 0.011147235948288177 1.2365806295535992e-10 9.907777560800003 -0.03592418988025692 T(ph)SPTVATQTGASATSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TSPTVATQTGASATSTR 17 0 Q6P1L5;Q6P1L5-2 Q6P1L5 FAM117B Protein FAM117B 1 T(0.798)S(0.196)PT(0.006)VATQTGASATSTR;T(0.497)S(0.497)PT(0.006)VATQTGASATSTR;T(0.571)S(0.426)PT(0.003)VATQTGASATSTR;T(0.984)S(0.016)PTVATQTGASATSTR 226.79 1.1629e-28 59249100.0 73346.4 77738.0 78703.5 87707.0 101070.0 81995.0 85051.0 68099.0 70860.0 65688.0 True False 85762.49686256655 85455.3148874559 80580.08992468573 82793.06113993074 81266.05903706569 77695.03785605203 76994.3535640837 66311.47340685481 71896.19344605065 77596.71441407793 1.105233610857719 1.1012749126392423 1.0384471885586246 1.0669660663481657 1.0472873710013946 1.001267108314012 0.9922372892390797 0.8545654788036271 0.9265365678035323 1.0 16.243707946924907 -7.044712072598986 1.2526870204130276 0.9215473727159423 1.078214192435876 0.7004255767839436 0.040350329954730695 0.23959281075690841 0.7623736782104582 0.02311474199775858 0.01607169194957697 9.021690570234975e-08 7.044712072598986 0.15666681971993357 T(ph)SPTVATQTGASATSTR ddPTM_PC-9_Lapatinib_30min_R1 3 TSPTVATQTGASATSTR 17 0 Q6P1L5;Q6P1L5-2 Q6P1L5 FAM117B Protein FAM117B 1 T(0.872)S(0.128)PT(0.001)VATQTGASATSTR;T(0.984)S(0.016)PTVATQTGASATSTR;T(0.837)S(0.163)PTVATQTGASATSTR 217.32 4.7086e-22 53867000.0 119774.0 98772.8 117029.0 101995.1 109931.0 112286.0 92652.3 104946.0 122779.0 78415.3 True False 118066.00079613843 98544.09765018255 107407.32736500398 109496.15989967961 103465.0747126616 107483.78953145044 97449.38274281443 109822.17428420867 108950.3360998124 91969.28012318038 1.2837547563491314 1.0714892790092094 1.1678609120474406 1.1905731974092257 1.1249960266524233 1.168692300162516 1.0595862293615237 1.194118015679983 1.1846383483037837 1.0 16.488864427512823 -11.27766358073464 2.6471742043165642 0.964956504629135 1.1563071520803248 0.3809395573694687 0.06120918962226999 14081718.035337923 11015963.580638222 3226659.3515447364 0.014182823645502045 5.276384298166578e-12 11.27766358073464 0.1913506474511898 T(ph)SPVKSNTPAAHLEIKPDELAK ddPTM_PC-9_AZD4547_30min_R2 1 TSPVKSNTPAAHLEIKPDELAK 22 2 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3 B8ZZZ7 SPATS2L SPATS2-like protein 1 T(0.762)S(0.231)PVKS(0.006)NT(0.002)PAAHLEIKPDELAK 75.945 0.00039619 5101400.0 36751.0 27707.0 38008.0 82744.0 69015.0 48365.0 40460.0 41551.0 41044.0 49553.0 True False 48437.05353171235 36662.745910084144 37503.989086013986 63668.6491820564 59433.45853561519 45340.72890431681 44060.86161859422 35130.24769699241 43213.502047013266 47818.16455275936 1.0129425498603184 0.7667116932025471 0.7843042374542544 1.33147413284357 1.242905475178586 0.9481904905465557 0.9214251954397041 0.7346632399123569 0.9037047417270562 1.0 15.545271134411802 -10.973523441192466 4.547085759565748 1.0001244075864772 0.9608423450906596 0.004016229157117079 0.1856420886229041 0.000260515398584371 3.1474018370310885e-05 0.20000149898309702 0.04835393122362741 1.0628612134317019e-11 10.973523441192466 -0.03928206249581767 T(ph)SPYGSSLDLSTGSSSRPPPK ddPTM_PC-9_AZD4547_30min_R2 2 TSPYGSSLDLSTGSSSRPPPK 21 1 J3KNZ9 J3KNZ9 FBRS 1 T(0.294)S(0.294)PY(0.291)GS(0.085)S(0.036)LDLSTGSSSRPPPK;T(0.551)S(0.148)PY(0.291)GS(0.007)S(0.003)LDLSTGSSSRPPPK 98.135 0.00019324 33578000.0 48802.0 49778.0 48580.0 68561.0 55160.0 66353.0 60794.0 77434.0 62577.0 65083.0 True False 64320.02085534069 65867.76503815535 47935.7974583919 52755.320706890816 47501.98613090685 62203.93642072017 66204.54822641652 65468.354556302096 65884.69246652251 62804.46397972341 1.0241313559511722 1.0487752122113634 0.7632546226947833 0.8399931687009224 0.7563472899990515 0.9904381389323358 1.054137620660067 1.0424156247466538 1.0490447380904893 1.0 15.938579485362675 -6.985750675892995 24.69476844376419 1.037413254112591 0.8848156335292178 0.38591127661888946 0.0902339365786564 231.9107091643714 401910.7014854521 0.03497899097141262 0.03083495396602705 1.0333544739489916e-07 6.985750675892995 -0.15259762058337334 T(ph)SPYGSSLDLSTGSSSRPPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSPYGSSLDLSTGSSSRPPPK 21 1 J3KNZ9 J3KNZ9 FBRS 1 T(0.371)S(0.371)PY(0.233)GS(0.02)S(0.005)LDLSTGSSSRPPPK 103.41 7.9927e-05 14746000.0 28074.0 34698.0 29603.0 37902.0 42353.0 31452.0 37163.0 26239.0 33062.0 27838.0 True False 32826.37371322512 38142.588128906726 30308.847790002674 35778.47381994195 34054.23368355443 29802.60175191839 33642.65160317973 25550.254052518572 33545.469202841115 32884.809034513266 0.9982230299337661 1.159884738539163 0.9216671368896481 1.0879939665269678 1.0355612419039388 0.9062726111816543 1.0230453693032273 0.7769622145502827 1.0200901324266312 1.0 15.00513367196682 -6.726645123096594 9.568078318440076 0.9362200063939741 1.043464273438771 0.223731990740892 0.0879654498565929 0.47330192265306176 124.0533074915637 0.02752968546557595 0.027346896832218425 1.8765272564769192e-07 6.726645123096594 0.10724426704479684 T(ph)SPYGSSLDLSTGSSSRPPPK ddPTM_PC-9_Lapatinib_30min_R1 2 TSPYGSSLDLSTGSSSRPPPK 21 1 J3KNZ9 J3KNZ9 FBRS 1 T(0.392)S(0.392)PY(0.215)GS(0.001)S(0.001)LDLSTGSSSRPPPK;T(0.685)S(0.275)PY(0.039)GSSLDLSTGSSSRPPPK 108.96 3.5889e-05 34102000.0 41379.0 78484.0 70351.0 69981.0 80822.0 74378.0 69686.0 73524.0 76352.0 57182.0 True False 40788.92787202074 78302.27512004251 64567.01234271324 75127.63618977231 76068.20886216564 71197.02632358638 73294.00010378323 76940.19345255823 67752.43373779616 67065.83250977442 0.6081923737556826 1.1675434746691684 0.9627407865741919 1.1202073153840733 1.1342319332437898 1.0615990834559441 1.0928664770261531 1.1472338532641742 1.0102377201971164 1.0 16.03329033490041 -4.755054610581261 24.99999999994802 1.081526926431095 0.6081915856809879 0.8237766080616494 0.06508067325041737 79.27300640318434 310369.9001329054 0.015133424525950694 0.13950555784220522 1.757702576854233e-05 4.755054610581261 -0.4733353407501071 T(ph)SPYILR ddPTM_PC-9_AZD4547_30min_R2 2 TSPYILR 7 0 P49454 P49454 CENPF Centromere protein F 1 T(0.711)S(0.289)PYILR;T(0.695)S(0.305)PYILR 143.89 0.0045341 46938000.0 113593.0 130481.0 142809.0 182835.0 196928.0 171666.0 147212.0 191332.0 153100.0 170308.0 True False 149713.21111882155 172656.43155497496 140915.25935025702 140685.21552259134 169587.94642471444 160931.69788252778 160313.58281256785 161766.03577196613 161192.55344015537 164345.56875772073 0.9109659131700089 1.0505694364629092 0.8574326671259095 0.8560329103244053 1.03189850329778 0.9792274844950295 0.9754664152150226 0.9843042133398963 0.980814722651795 1.0 17.326373032057063 -6.2756575725304 24.995267423992683 0.9897066043598115 0.9237860582573488 0.3161045456965812 0.05247723713059306 1140.785012596969 2005470.680443809 0.017048340666349943 0.019418735823407564 5.300812314573802e-07 6.2756575725304 -0.06592054610246267 T(ph)SPYILR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSPYILR 7 0 P49454 P49454 CENPF Centromere protein F 1 T(0.694)S(0.306)PYILR 115.49 0.020059 16311000.0 51201.0 54550.0 46195.0 47133.0 72225.0 46085.0 64230.0 46591.0 47825.0 32906.0 True False 59868.318034153985 59965.36349160934 47296.46399551311 44492.290817247725 58073.02972150065 43668.22147199413 58145.66941506964 45368.03561724501 48524.35014898908 38871.59731624732 1.5401558507381066 1.5426524154320096 1.216735798396029 1.1445964120093184 1.4939707583672575 1.123396631137202 1.495839467105363 1.1671255813890198 1.2483240591892826 1.0 15.24642877183888 -1.8655537033334741 0.034215508737826 7.427731623718678e-06 3.233633038712701 0.4050090583949618 0.14737891861142122 1078.0346037568006 2.99649464847893 87.09844947344722 225.94351457626502 0.013628444712171395 1.8655537033334741 3.2336256109810773 T(ph)SPYILR ddPTM_PC-9_Lapatinib_30min_R1 2 TSPYILR 7 0 P49454 P49454 CENPF Centromere protein F 1 T(0.998)S(0.002)PYILR;T(0.878)S(0.122)PYILR 180.93 0.00049446 25165700.0 104359.0 140630.0 145168.0 124273.0 123697.0 129082.0 98921.0 93494.0 108745.0 86516.0 True False 102870.82152290313 140304.37987528113 133232.8474046851 133412.4509825755 116421.38565765898 123561.46376483874 104042.64535582963 97838.07255662735 96496.99296438378 101470.17532467654 1.0138035259498164 1.3827154572892562 1.3130247087715852 1.3147947222490994 1.147345860841796 1.2177121343239645 1.0253519817317935 0.9642052183666041 0.950988728023974 1.0 16.63069621924562 -7.246804915833711 1.5307375096278772 0.9596881591607958 1.257332780568711 0.6073303522367912 0.09713884791197254 0.26093307949886696 1.1947271065692928 0.05511025354698425 0.033367338602542186 5.6649369967000475e-08 7.246804915833711 0.29764462140791514 T(ph)SQDYQALTVHDNLAMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSQDYQALTVHDNLAMK 17 0 Q9BPX3 Q9BPX3 NCAPG Condensin complex subunit 3 1 T(0.497)S(0.497)QDY(0.006)QALT(0.001)VHDNLAMK 60.635 0.034827 3673300.0 20986.0 29741.0 23547.0 27728.0 32311.0 23498.0 25935.0 19430.0 25549.0 19136.0 True False 24538.51530760641 32693.489928578434 24108.449782494783 26174.49005538891 25979.891496454242 22265.723514135152 23478.24904686023 18919.98308778671 25922.605791040703 22605.205319507346 1.085524991291749 1.4462814854579233 1.0664999252048466 1.1578965855621501 1.1492880126169296 0.9849821401498514 1.0386213580019767 0.8369746180301029 1.1467538305732874 1.0 14.464367401036903 -6.311792396404984 0.9436821596263495 0.9860134536185158 1.2401577887428339 0.3491104874278106 0.12091669375443054 0.5726098971595625 1.09073748151034 0.056596278562768776 0.08509871253196338 4.877615965930645e-07 6.311792396404984 0.2541443351243181 T(ph)SQETADVK ddPTM_PC-9_Lapatinib_30min_R1 1 TSQETADVK 9 0 H3BVG0;Q8N1F7;H3BNN5;H3BV11;H3BRI8;H3BM93 H3BVG0 NUP93 Nuclear pore complex protein Nup93 1 T(0.961)S(0.039)QETADVK 130.69 0.0030756 24183000.0 163250.0 194340.0 198070.0 202120.0 183150.0 194470.0 183340.0 172730.0 187880.0 133970.0 True False 160922.0250636168 193890.01767021383 181785.4491723102 216984.5790525545 172377.47708675428 186152.97143171154 192832.44811049037 180755.66638186693 166718.9759358906 157126.535996196 1.0241556210945342 1.2339737297773041 1.1569366563055345 1.380954386073958 1.0970615242922908 1.1847328667400792 1.2272430426084031 1.1503828123993198 1.0610491402924254 1.0 17.261567322269634 -8.32166330499065 2.180658181969204 1.002968690071663 1.1912954730791423 0.33526804093386975 0.08805244855755467 0.33017741893898883 2.9785644255495893 0.08044785651036544 0.022907167660229037 4.768004921514631e-09 8.32166330499065 0.1883267830074793 T(ph)SQSEEEEAPR ddPTM_PC-9_AZD4547_30min_R2 1 TSQSEEEEAPR 11 0 Q7RTP6;A0A5F9ZHV5;J3KSK6;Q7RTP6-2;Q7RTP6-4;Q7RTP6-3;Q7RTP6-5 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 T(0.986)S(0.014)QSEEEEAPR 128.21 0.00083151 0.0 4060.6 4205.2 4557.8 7478.2 5049.3 7078.9 3839.6 5592.5 6175.7 6028.5 True False 5351.786334273114 5564.4486628319855 4497.360593986384 5754.216527038269 4348.291852262292 6636.255263946414 4181.316961709201 4728.307627865278 6502.134894058569 5817.44404993259 0.9199549300925599 0.956510903254233 0.7730818819028431 0.9891313913203766 0.7474574426397239 1.1407510251900594 0.7187549937429397 0.8127809373465427 1.1176961631687568 1.0 12.506169715041667 -8.263766834320075 24.996128455904774 1.0588480894639158 0.8833652711652351 0.2448666086149014 0.124000502910557 289.9317833360827 3113668.8422815627 0.09682035966441398 0.02956501975773208 5.447950659949437e-09 8.263766834320075 -0.17548281829868073 T(ph)SQSEEEEAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSQSEEEEAPR 11 0 Q7RTP6;A0A5F9ZHV5;J3KSK6;Q7RTP6-2;Q7RTP6-4;Q7RTP6-3;Q7RTP6-5 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 T(0.864)S(0.136)QSEEEEAPR 111.88 0.004297100000000001 1808000.0 5428.6 6435.7 5555.9 9096.3 10388.0 6920.1 9309.0 7757.2 7908.9 6221.5 True False 6347.55476026266 7074.593763940424 5688.373726868084 8586.6638016025 8352.545970881954 6557.197773860188 8427.184128676374 7553.581719432789 8024.5527003312045 7349.408700633097 0.8636823748440967 0.962607204485852 0.7739906649058819 1.1683475707185562 1.1364922419081747 0.8922075286540173 1.146647910321062 1.0277808769543737 1.0918637168239056 1.0 12.843412466722626 -5.761510259155963 24.999999999817742 1.0663811692780474 0.8763447967016508 0.5204152007406767 0.08758750558753779 1.5365509283718206 542254.6463307921 0.023826638169956196 0.03806457893314481 1.7317681214366503e-06 5.761510259155963 -0.1900363725763966 T(ph)SQVGAASAPAKESPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSQVGAASAPAKESPR 16 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 T(0.495)S(0.495)QVGAAS(0.006)APAKES(0.003)PR 111.5 0.00466 2267200.0 8978.0 8406.4 7943.8 9850.5 10808.0 11435.0 10592.0 12596.0 10628.0 8990.0 True False 10497.79807641715 9240.931836037847 8133.21031902926 9298.608420751887 8690.249985877183 10835.328469832983 9588.649080560761 12265.36834656518 10783.414393799392 10619.815835199155 0.9885103696075802 0.8701593303914908 0.7658522939797041 0.8755903647530163 0.8183051496122496 1.0202934436884974 0.9029016349586201 1.1549511344548815 1.0154050278403128 1.0 13.374471127240607 -7.13335458445725 1.466742924015012 1.0498254181325866 0.8608852515921783 0.455199479374197 0.08079329891294296 0.3469267972979924 1.4813289437742558 0.043797316408340586 0.02892341389719907 7.356062585101664e-08 7.13335458445725 -0.18894016654040824 T(ph)SRDTSPSSGSAVSSSK ddPTM_PC-9_AZD4547_30min_R2 1 TSRDTSPSSGSAVSSSK 17 1 F8WF16;B7Z8L1;F8W6A0;F8W0Q9;Q8NEY8-5;Q8NEY8-6;Q8NEY8-9;Q8NEY8-8;Q8NEY8-2;Q8NEY8-3;Q8NEY8;Q8NEY8-7 F8WF16 PPHLN1 Periphilin-1 1 T(0.417)S(0.417)RDT(0.09)S(0.072)PS(0.003)S(0.001)GSAVSSSK 57.196999999999996 0.033408999999999994 2232200.0 6310.4 3755.6 8233.9 36913.0 18828.0 7493.6 7032.6 9616.1 4429.0 11144.0 True False 8316.975935526036 4969.524255239186 8124.713106065313 28403.278150164937 16214.05719493681 7025.024007389403 7658.487776048586 8130.1527009951305 4663.107898017294 10753.851951969613 0.773395056271232 0.462115740242174 0.7555165481497296 2.6412190047830033 1.507744133669902 0.6532565297314457 0.7121622847565706 0.7560223757317078 0.43362210293059006 1.0 13.392565894863019 -6.7772747637304365 24.538683426081107 0.6958357171882286 1.237712368539854 0.16978393816969628 0.5709094263918815 397.4316970484821 615859.9253677871 0.22466200375705536 0.19881727637187738 1.6700337050136044e-07 6.7772747637304365 0.5418766513516253 T(ph)SSAELSTSAPDEPLLQK ddPTM_PC-9_Lapatinib_30min_R1 1 TSSAELSTSAPDEPLLQK 18 0 Q15139 Q15139 PRKD1 Serine/threonine-protein kinase D1 1 T(0.457)S(0.086)S(0.457)AELSTSAPDEPLLQK 153.92 4.6184e-05 2857400.0 18144.0 16096.0 15912.0 13132.0 18008.0 16854.0 16915.0 15699.0 15258.0 12922.0 True False 17885.263232797897 16058.730700935286 14603.77678209625 14097.771087067811 16948.8048450902 16133.193708592935 17790.775934269353 16428.432852017188 13539.483366137016 15155.550482517303 1.1801130716716266 1.0595940226295208 0.9635926322136863 0.9302051484919869 1.1183232746736258 1.064507272579996 1.1738785704149721 1.0839878677431227 0.8933679698243556 1.0 13.88755863444137 -8.252303649567985 0.007572719874268005 5.453919087796419e-08 2.073401913486009 0.06667982669791539 0.09018625654792939 9092.257785541091 59.52271448101906 8189.105065592535 8100.8240207226345 5.5936636753976954e-09 8.252303649567985 2.073401858946818 T(ph)SSDSALHTSVMNPSPQDTYPGPTPPSILPSR ddPTM_PC-9_AZD4547_30min_R2 1 TSSDSALHTSVMNPSPQDTYPGPTPPSILPSR 32 0 Q53ET0;H0YDQ8 Q53ET0 CRTC2 CREB-regulated transcription coactivator 2 1 T(0.317)S(0.317)S(0.317)DS(0.019)ALHT(0.023)S(0.004)VMNPS(0.001)PQDTYPGPTPPSILPSR 77.032 5.8771e-07 9054600.0 4028.6 3777.6 12882.0 32714.0 14320.0 16798.0 9542.8 22270.0 8589.3 15561.0 True False 5309.610999914459 4998.635325005734 12711.176263050724 25172.292726261636 12331.915181192637 15747.618404522149 10392.090713146838 18828.683213689717 9043.312862596513 15016.214126399771 0.35359185445948826 0.33288252837429316 0.846496737197121 1.676340821619387 0.8212399661717723 1.0487076350913582 0.6920579731795823 1.2538901653371675 0.6022365415459551 1.0 13.874233507346359 -5.333895880322817 4.375062632572717 1.0193561838898768 0.3394810129763236 0.4576186259260423 0.2859279413069292 0.17494171957545926 6.368491219553524 0.07432262038343529 0.16821346214504737 4.635580418675935e-06 5.333895880322817 -0.6798751709135532 T(ph)SSEDNLYLAVLR ddPTM_PC-9_AZD4547_30min_R2 4 TSSEDNLYLAVLR 13 0 Q15149-4 Q15149-4 PLEC Plectin 1 T(0.767)S(0.117)S(0.117)EDNLYLAVLR;T(0.95)S(0.016)S(0.034)EDNLYLAVLR;T(0.482)S(0.482)S(0.036)EDNLYLAVLR;T(0.851)S(0.09)S(0.058)EDNLYLAVLR 249.58 4.9527e-34 57398640.0 56469.2 64667.0 83427.29000000001 112639.36 110221.9 91974.5 87763.87 120255.98999999999 95352.4 95456.73000000001 True False 74425.23096767346 85569.34311789111 82320.98962417716 86672.09581276406 94919.49175348456 86223.31997539717 95574.68440885526 101673.18995323914 100392.5331982172 92114.81893746734 0.8079615400231904 0.9289422060958545 0.8936780267685401 0.9409137076152959 1.030447574541955 0.9360417896921706 1.0375603568600256 1.1037658340539165 1.089863003111033 1.0 16.491145647568743 -5.846283532289103 0.5111702406022108 1.0693057322182988 0.8050377373037007 0.715260183785317 0.04672264128590754 0.9331992968446886 0.3917809361406243 0.03582371889823894 0.1324828778965922 1.424677179135529e-06 5.846283532289103 -0.2642679949145982 T(ph)SSEDNLYLAVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSEDNLYLAVLR 13 0 Q15149-4 Q15149-4 PLEC Plectin 1 T(0.862)S(0.01)S(0.128)EDNLYLAVLR 260.73 5.5167e-44 315570000.0 509560.0 678420.0 744330.0 940580.0 1369100.0 897860.0 1112300.0 1069400.0 857260.0 900680.0 True False 595818.443731246 745769.0540784168 762077.6500872457 887882.3520015043 1100834.683166585 850774.6410078049 1006934.8916453696 1041329.3831229575 869795.8057234164 1063966.1542210446 0.5599975538389744 0.7009330617517738 0.7162611771660925 0.8345024402130014 1.0346519753464645 0.7996256625575441 0.9463974842156243 0.9787241624103541 0.8175032657502296 1.0 20.02102082738687 -5.576762556113649 1.3395482762487032 0.925633637499973 0.5973784785550296 0.7214066603476856 0.0763533980914799 0.26363189137313175 0.8861538233766666 0.02434399825205921 0.0789294096528398 2.6499485615916704e-06 5.576762556113649 -0.3282551589449434 T(ph)SSEDNLYLAVLR ddPTM_PC-9_Lapatinib_30min_R1 5 TSSEDNLYLAVLR 13 0 Q15149-4 Q15149-4 PLEC Plectin 1 T(0.641)S(0.006)S(0.353)EDNLYLAVLR;T(0.69)S(0.015)S(0.296)EDNLYLAVLR;T(0.848)S(0.094)S(0.058)EDNLYLAVLR;T(0.389)S(0.389)S(0.222)EDNLYLAVLR;T(0.523)S(0.106)S(0.371)EDNLYLAVLR 250.52 3.4179e-34 377224400.0 1471382.0 1459480.0 1537972.0 1415489.0 1666636.0 1632175.0 1518405.0 1474097.0 1672799.0 1252631.0 True False 1450399.8228615855 1456100.6637301852 1411525.878903605 1519588.7829928831 1568607.7472124458 1562370.6800357578 1597020.5812872755 1542588.9280756712 1484390.761265607 1469146.599324113 0.9872396829076472 0.9911200586790117 0.9607794617317179 1.0343343432792726 1.067699947666278 1.063454580199507 1.0870396337724169 1.0499897891642302 1.0103762020403595 1.0 20.486546932247187 -5.89315406439061 5.111896295672187 1.0517321331475828 0.9812934860416677 0.5698933079772929 0.025735592951902458 0.14125555252043154 5.81060911870111 0.007396095408564262 0.011181493263881254 1.2789275287774207e-06 5.89315406439061 -0.07043864710591519 T(ph)SSFTEQLDEGTPNRENASTHASK ddPTM_PC-9_AZD4547_30min_R2 1 TSSFTEQLDEGTPNRENASTHASK 24 1 Q13439-5;E7EVX2;C9JHJ5 Q13439-5 GOLGA4 Golgin subfamily A member 4 1 T(0.423)S(0.14)S(0.423)FT(0.014)EQLDEGTPNRENASTHASK 79.993 0.00010127 9005300.0 5050.5 4065.3 23693.0 66708.0 36163.0 30003.0 15137.0 35448.0 20071.0 31710.0 True False 6656.453943074013 5379.328723725599 23378.81533926882 51329.50122832609 31142.39166881769 28126.90766703644 16484.163675745443 29970.32611400417 21131.91208424139 30599.84255177283 0.21753229389372677 0.1757959608656203 0.7640175043290981 1.6774433117255458 1.0177304545318135 0.9191847186614653 0.5387009311520271 0.9794274615399226 0.6905889155634591 1.0 14.901236609252967 -5.343292864730306 4.3362512336263 0.9706875735086575 0.1940115329412412 0.5429258745838332 0.27990680220117176 0.1666470239048106 5.690700848849048 0.07969041283618518 0.1795006897886664 4.536356061439815e-06 5.343292864730306 -0.7766760405674163 T(ph)SSGLGGSTTDFLEEWK ddPTM_PC-9_Lapatinib_30min_R1 1 TSSGLGGSTTDFLEEWK 17 0 Q96IZ0;A0A0B4J260;F8W1M8 Q96IZ0 PAWR PRKC apoptosis WT1 regulator protein 1 T(0.483)S(0.118)S(0.088)GLGGS(0.216)T(0.071)T(0.024)DFLEEWK 91.59200000000001 0.010176000000000001 0.0 5530.7 7099.6 7058.1 7281.8 7478.3 5413.9 4984.5 5313.9 5875.5 4407.7 True False 5451.83120379384 7083.161312398125 6477.810263053895 7817.3278633726995 7038.441096903492 5182.360117417302 5242.57302065419 5560.8031933457 5213.739318242104 5169.565072108928 1.0546015240639504 1.3701658096178184 1.253066780801981 1.5121828924350138 1.3615151369072822 1.0024750719122206 1.0141226481390395 1.0756810516512496 1.008545060467757 1.0 12.335827192918726 -6.763523887041861 24.998523085889346 1.0245171597973017 1.3216673501960052 0.6354056685152439 0.10969694318127883 36.179754980298014 433882.0015411872 0.03821449114515398 0.03536476771745784 1.723757278413933e-07 6.763523887041861 0.2971501903987035 T(ph)SSGTSLSAMHSSGSSGK ddPTM_PC-9_AZD4547_30min_R2 1 TSSGTSLSAMHSSGSSGK 18 0 Q12888;Q12888-3;Q12888-2;A6NNK5;M0R142 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 T(0.423)S(0.114)S(0.131)GT(0.15)S(0.032)LS(0.15)AMHSSGSSGK 62.589 0.020325 5671100.0 5390.5 4639.4 37641.0 132000.0 55756.0 35339.0 14793.0 63459.0 19665.0 34426.0 True False 7104.566870634684 6138.995321588205 37141.85574580749 101569.43937967031 48015.24181861569 33129.24674350566 16109.548342161746 53652.86969274966 20704.451753106816 33220.7562184589 0.21385927592723122 0.18479396679649068 1.1180316155828462 3.0574090099500477 1.4453386161009885 0.9972454126464951 0.4849241912563863 1.6150405890802024 0.6232384241031371 1.0 15.019797293915452 -3.2320895119728856 9.984219256258921 1.1145118595446917 0.8947006887289778 0.0 0.8046727359696292 0.0 0.0 0.19842266828791116 0.0 0.0005860173686505042 3.2320895119728856 -0.21981117081571389 T(ph)SSIADEGTYTLDSILR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSSIADEGTYTLDSILR 17 0 E7ERV5;A0A087WY00;G3V394;F8WE88;F8W6H6;Q9Y4I1-2;Q9Y4I1;Q9Y4I1-3 E7ERV5 MYO5A Unconventional myosin-Va 1 T(0.333)S(0.333)S(0.333)IADEGTYTLDSILR;T(0.487)S(0.025)S(0.487)IADEGTYTLDSILR 168.05 4.8411e-05 2680500.0 5047.700000000001 7718.5 7318.6 8486.7 7631.200000000001 6539.0 11054.0 7343.0 9582.1 5098.6 True False 5902.175913380583 8484.741670210573 7493.1031799450575 8011.217713252632 6135.921141027568 6196.083328748392 10006.88509597042 7150.254030551614 9722.220084947794 6022.935819504608 0.9799499928700954 1.4087385163118757 1.2440948076649723 1.330118392978586 1.0187591774026663 1.0287480249553822 1.6614630133637212 1.1871708822458826 1.6141995160339357 1.0 12.556251170284677 -7.235428561166761 24.997955299529423 1.3813060617954496 1.1833153644385335 0.1583880612087537 0.2200450610626793 1380.8093595092885 1327042.310739006 0.08044300494841121 0.06229123323052843 5.815290824818112e-08 7.235428561166761 -0.1979906973569161 T(ph)SSIATALNTSGAGGSRPAQAVR ddPTM_PC-9_AZD4547_30min_R2 1 TSSIATALNTSGAGGSRPAQAVR 23 1 Q8N4C8;Q8N4C8-4;Q8N4C8-3;Q8N4C8-2;Q8N4C8-5 Q8N4C8;Q8N4C8-3 MINK1 Misshapen-like kinase 1 1 T(0.863)S(0.068)S(0.022)IAT(0.046)ALNTSGAGGSRPAQAVR 86.508 2.2062e-05 26685000.0 6983.9 6250.9 6572.4 11081.0 8766.8 9716.7 6828.4 7392.0 5810.4 7505.2 True False 9204.634925855778 8271.381181988127 6485.245681670124 8526.446649743395 7549.68114598322 9109.113212955137 7436.114371636401 6249.736251261535 6117.525881833298 7242.445232405087 1.2709291724666703 1.142070242378809 0.8954497374247302 1.1772883848114255 1.0424215722341204 1.2577400202072584 1.026740849673916 0.8629317931598784 0.8446768578188856 1.0 12.822261154494482 -7.580571869194262 4.6217218323238285 0.8936701054346764 1.1207917578076447 0.4699087411969153 0.10817229039033822 0.1853775012460081 8.170832689349924 0.053231127570249746 0.03010428119383611 2.626806793546559e-08 7.580571869194262 0.22712165237296833 T(ph)SSISGPLSPAYTGQVPYNYNQLEGR ddPTM_PC-9_Lapatinib_30min_R1 1 TSSISGPLSPAYTGQVPYNYNQLEGR 26 0 Q01082-3 Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 T(0.263)S(0.263)S(0.21)IS(0.263)GPLSPAYTGQVPYNYNQLEGR 114.68 2.5351999999999996e-11 22516000.0 21415.0 17714.0 18458.0 17652.0 13743.0 14053.0 15756.0 9615.7 12718.0 11450.0 True False 21109.61817296996 17672.984321344924 16940.454489940457 18950.186965345798 12934.663759777573 13451.985949143016 16571.768585299902 10062.48052583869 11285.564913522781 13429.117243834022 1.5719289503308522 1.316019809824765 1.2614719331398097 1.4111267793158015 0.9631804924271193 1.001702919476669 1.2340177157146222 0.7493032001384065 0.8403802505115925 1.0 13.713076852609662 -5.932070400838562 0.5121247393210883 0.8801801333664004 1.5895936104017456 0.6737160342646373 0.14300850010465121 0.974116229120777 0.4311517863452025 0.11165544806650905 0.36815285371416 1.1693098259475397e-06 5.932070400838562 0.7094134770353452 T(ph)SSLDTITGPYLTGQWPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSLDTITGPYLTGQWPR 18 0 Q86VQ1;H7C0Q2;H7C2L5 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 T(0.52)S(0.068)S(0.412)LDTITGPYLTGQWPR 102.08 0.0011878 10091000.0 6190.4 6386.2 9242.7 9408.5 11641.0 11036.0 6456.6 6313.9 7669.4 7834.2 True False 7238.312454026819 7020.179731074532 9463.081021134944 8881.37224776855 9360.029615617708 10457.25273223234 5844.9841062640335 6148.166815130036 7781.550465920682 9254.478444506927 0.7821415866307604 0.7585710824407851 1.022540716678835 0.9596837143253775 1.011405415415218 1.1299667285344783 0.6315843881762319 0.6643450359732949 0.8408416003755983 1.0 13.175935970951796 -10.993384473440797 6.184734231908692 1.0000690282880096 0.870039349623428 0.062285646566876185 0.1546007778561738 0.00016222388792989204 1.3888376055431474e-05 0.1650239769994939 0.0400029840993348 1.0153494234813253e-11 10.993384473440797 -0.1300296786645816 T(ph)SSLDTITGPYLTGQWPR ddPTM_PC-9_Lapatinib_30min_R1 1 TSSLDTITGPYLTGQWPR 18 0 Q86VQ1;H7C0Q2;H7C2L5 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 T(0.475)S(0.475)S(0.05)LDTITGPYLTGQWPR 208.38 5.7151e-20 13877000.0 27240.0 23048.0 27504.0 19385.0 27648.0 26681.0 23789.0 25835.0 26390.0 19448.0 True False 26851.552604795805 22994.63377206489 25242.727288510276 20810.637566464316 26021.7989980594 25539.915826448792 25020.67801952905 27035.38841530441 23417.680300980188 22809.5608871689 1.1772060294199111 1.0081138293635499 1.1066730926288944 0.9123646732792194 1.1408285817855215 1.1197022140314767 1.096938171817414 1.1852656238776027 1.0266607242822186 1.0 14.477351052766721 T(ph)SSLDTLAAPYLAGHWPR ddPTM_PC-9_AZD4547_30min_R2 1 TSSLDTLAAPYLAGHWPR 18 0 Q6P1L5;Q6P1L5-2 Q6P1L5 FAM117B Protein FAM117B 1 T(0.472)S(0.472)S(0.032)LDT(0.024)LAAPYLAGHWPR 104.68 0.00075558 8385400.0 33074.0 25059.0 29216.0 41731.0 34767.0 37805.0 29038.0 26834.0 20545.0 28709.0 True False 43590.84401806357 33158.831694546454 28828.576750604716 32110.562687522895 29940.20217210366 35441.04737367303 31622.325745940176 22687.421883976192 21630.96675655122 27703.90664833952 1.5734547683612072 1.196900932256566 1.0405960833084384 1.1590626222907625 1.080721305920881 1.27927977175007 1.1414392254254695 0.8189250047641204 0.7807912086596533 1.0 14.75780181087018 -1.5228787452803376 0.34978740808664655 0.9575841668361333 6.957647657452759 0.5673544015001266 0.14186658808099367 54.95499612714453 0.7737117406301951 0.13513928279179077 217.41885537783932 0.029999999999999995 1.5228787452803376 6.0000634906166255 T(ph)SSLDTLAAPYLAGHWPR ddPTM_PC-9_Lapatinib_30min_R1 1 TSSLDTLAAPYLAGHWPR 18 0 Q6P1L5;Q6P1L5-2 Q6P1L5 FAM117B Protein FAM117B 1 T(0.38)S(0.38)S(0.239)LDT(0.001)LAAPYLAGHWPR 212.41 5.4728e-21 4981800.0 18049.0 19159.0 17497.0 14769.0 21148.0 16716.0 17806.0 19503.0 17896.0 15299.0 True False 17791.61795021878 19114.63851262545 16058.464200373179 15855.161527939727 19904.116218567724 16001.095646899217 18727.90755457287 20409.18057920193 15880.364026765488 17943.411765363904 0.9915404151044379 1.0652733584101526 0.8949504369827129 0.8836202242510469 1.1092715520795526 0.8917532438165449 1.0437205476565652 1.1374191734594026 0.8850247787000737 1.0 14.131166610330217 T(ph)SSLTQFPPSQSEER ddPTM_PC-9_AZD4547_30min_R2 1 TSSLTQFPPSQSEER 15 0 B7Z7F3;Q9H6Z4-3;Q9H6Z4-2;Q9H6Z4 B7Z7F3 RANBP3 Ran-binding protein 3 1 T(0.767)S(0.116)S(0.116)LTQFPPSQSEER 284.53 1.3231999999999998e-88 16833000.0 93158.0 74632.0 120650.0 157680.0 124020.0 124230.0 89943.0 111510.0 90542.0 109430.0 True False 122780.30619322641 98755.33449169534 119050.10216869041 121329.3121317153 106801.96374102742 116461.87846135187 97947.75275732126 94278.69174488289 95327.86527484345 105598.88900789992 1.1627045260300146 0.9351929307164148 1.1273802526443644 1.1489639074009441 1.0113928730162822 1.1028703005827956 0.9275452959547114 0.8928000344570844 0.902735494383013 1.0 16.688235130807186 -7.269208422862267 23.30245705171943 0.9218368390256343 1.0767474708827864 0.5320512945885811 0.06892669069553564 182.6877170557378 547948.1408751885 0.02768738170794301 0.019099264939618808 5.380115227003345e-08 7.269208422862267 0.15491063185715215 T(ph)SSLTQFPPSQSEER ddPTM_PC-9_Lapatinib_30min_R1 1 TSSLTQFPPSQSEER 15 0 B7Z7F3;Q9H6Z4-3;Q9H6Z4-2;Q9H6Z4 B7Z7F3 RANBP3 Ran-binding protein 3 1 T(0.865)S(0.027)S(0.108)LTQFPPSQSEER 128.71 4.2063999999999996e-05 10286000.0 15614.0 17538.0 21705.0 20471.0 31183.0 37599.0 37808.0 36556.0 38482.0 35589.0 True False 15391.341496743084 17497.391838531512 19920.498683722915 21976.505629254123 29348.877248136825 35990.97841754987 39765.513244035246 38254.52521423912 34147.751926575205 41740.51123063835 0.3687386915722666 0.4191944785210988 0.47724615957987787 0.5265030298220913 0.7031269235292493 0.8622553331625653 0.9526839051948789 0.9164843478524419 0.8180961593376481 1.0 15.349160650037375 -6.369338428496951 1.2170952768036432 0.9236411079307787 0.40306879808942897 0.9567630003768386 0.046917254570127825 0.08699067494883045 0.26616826034018426 0.02029751709021769 0.026558832014440065 4.2722983310509606e-07 6.369338428496951 -0.5205723098413497 down T(ph)SSNASTISGR ddPTM_PC-9_Lapatinib_30min_R1 1 TSSNASTISGR 11 0 Q12778 Q12778 FOXO1 Forkhead box protein O1 1 T(0.608)S(0.016)S(0.318)NAS(0.046)T(0.013)ISGR 83.137 0.032195999999999995 3014400.0 9155.2 13973.0 11502.0 11170.0 18611.0 16900.0 17433.0 17445.0 17756.0 15083.0 True False 9024.64516914194 13940.64637699856 10556.34995900397 11991.479062027678 17516.33757063382 16177.22639582416 18335.5954396759 18255.558386103567 15756.132301030857 17690.076453165813 0.5101529771809942 0.7880489614562262 0.5967385153451277 0.6778647392381215 0.9901787376107749 0.9144802985251704 1.0364904576992129 1.0319660536479227 0.8906763259472031 1.0 14.110652662646494 -6.235358253074801 5.161313710547915 0.9795620373609905 0.647024355880273 0.8165319036422329 0.07763996706084968 0.07665737307521714 5.961108244697456 0.022460171978478386 0.028291866844448108 5.816232340578314e-07 6.235358253074801 -0.3325376814807175 T(ph)SSPLFNK ddPTM_PC-9_Lapatinib_30min_R1 1 TSSPLFNK 8 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 T(0.767)S(0.116)S(0.116)PLFNK 125.71 0.008461 34375000.0 340440.0 303160.0 292790.0 296950.0 281250.0 273750.0 258630.0 241040.0 249120.0 215130.0 True False 335585.26317095 302458.05164609494 268717.93640208367 318788.6935961614 264707.42795877485 262042.35064241826 272020.59591369104 252239.59835978167 221061.48225010172 252314.93385729418 1.3300253696467779 1.198732262978778 1.0650100344598183 1.2634555106296794 1.0491151828075689 1.0385526795279814 1.0780994678164477 0.9997014227562324 0.8761331676670832 1.0 17.94486607260299 -4.226841695643559 0.2810025071314468 0.940412236200429 1.7018820310550404 0.6852224575011845 0.07241657393722571 7.056184564379401 0.36133274246591124 0.08873017338364156 1.9534082738477565 5.931414907410268e-05 4.226841695643559 0.7614697948546114 T(ph)SSPRSPPSSSEIFTPAHEENVR ddPTM_PC-9_AZD4547_30min_R2 1 TSSPRSPPSSSEIFTPAHEENVR 23 1 I3L3A7;I3L2L5;I3L317;I3L4Q0;C9JLW8 I3L3A7 FAM195B Protein FAM195B 1 T(0.309)S(0.309)S(0.309)PRS(0.067)PPS(0.004)S(0.001)SEIFTPAHEENVR 90.729 1.2014e-05 32669000.0 8093.6 3503.4 15747.0 28046.0 22763.0 17945.0 9180.0 15868.0 11828.0 13485.0 True False 10667.196442661885 4635.805537278987 15538.184491092989 21580.428006380575 19602.750367981018 16822.896313200967 9997.002215983566 13415.965210364991 12453.20393265942 13012.89425451455 0.8197405000014601 0.35624707667709604 1.1940606130494253 1.6583880253152523 1.5064097182823304 1.2927866763663753 0.7682381813342806 1.0309747353637801 0.9569895589014753 1.0 13.66765425338473 -5.276052048300355 24.06293093833489 1.1957264756001273 0.5879938228061308 0.428834108025981 0.27066767989098883 419.81267576985573 691313.3974576179 0.07880607396159184 0.16532582922886227 5.2959996984058865e-06 5.276052048300355 -0.6077326527939966 T(ph)SSPRSPPSSSEIFTPAHEENVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSSPRSPPSSSEIFTPAHEENVR 23 1 I3L3A7;I3L2L5;I3L317;I3L4Q0;C9JLW8 I3L3A7 FAM195B Protein FAM195B 1 T(0.597)S(0.183)S(0.183)PRS(0.035)PPS(0.001)S(0.001)SEIFTPAHEENVR;T(0.309)S(0.309)S(0.309)PRS(0.072)PPS(0.001)S(0.001)SEIFTPAHEENVR;T(0.589)S(0.146)S(0.146)PRS(0.119)PPSSSEIFTPAHEENVR 95.366 6.0148e-06 27337000.0 17355.399999999998 6532.4 21018.6 26985.0 38380.4 37905.3 29063.5 39261.4 37702.5 21966.3 True False 20293.32643522503 7180.893500872388 21519.76313748438 25473.117936550396 30860.03613600671 35917.47933953303 26310.394878481668 38230.829850891874 38253.827736377665 25948.61630486489 0.7820581335360223 0.2767351220776309 0.8293221836822883 0.9816753863586419 1.1892748258110788 1.3841770565931548 1.0139421142679177 1.473328265435267 1.4742145510551088 1.0 14.66336998929511 -5.83361758459178 1.5241580182477008 1.28140532910264 0.5250604296673825 0.6741044244634604 0.19908870952153887 0.21693064651062605 1.0242058268448861 0.06440494227960153 0.1337212877911014 1.466838888669549e-06 5.83361758459178 -0.7563448994352574 T(ph)SSPRSPPSSSEIFTPAHEENVR ddPTM_PC-9_Lapatinib_30min_R1 2 TSSPRSPPSSSEIFTPAHEENVR 23 1 I3L3A7;I3L2L5;I3L317;I3L4Q0;C9JLW8 I3L3A7 FAM195B Protein FAM195B 1 T(0.306)S(0.306)S(0.306)PRS(0.082)PPS(0.001)S(0.001)SEIFTPAHEENVR;T(0.3)S(0.3)S(0.3)PRS(0.081)PPS(0.012)S(0.004)S(0.001)EIFTPAHEENVR 112.82 1.7995999999999998e-07 46300000.0 111106.0 46647.0 85418.0 62348.0 63454.0 62144.0 45983.0 42924.0 87792.0 46489.0 True False 109521.6080656549 46538.99173748312 78395.26176301514 66933.27990683084 59721.760475363924 59486.24598473942 48363.77474345301 44918.40574176605 77903.94046925554 54524.56170730129 2.008665537810074 0.8535417852107404 1.4377971928294724 1.2275803383095865 1.0953184877663433 1.0909990676142147 0.8870089594315198 0.823819657329792 1.4287861842422396 1.0 15.734618647437129 -4.751941694806003 24.99968091813276 1.096783709885345 2.0086673386594853 0.6361628087336623 0.20753506326604582 249.73541454718426 657303.9647338488 0.051809673006090566 0.649547480331221 1.770346616124964e-05 4.751941694806003 0.9118836287741403 T(ph)SSPSVEDATPALGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSPSVEDATPALGVR 16 0 K7ER94;Q2V2M9-2;Q2V2M9;Q2V2M9-3;Q2V2M9-4;A0A0A0MTS9;K7EP24 K7ER94 FHOD3 FH1/FH2 domain-containing protein 3 1 T(0.97)S(0.017)S(0.013)PS(0.001)VEDATPALGVR 108.06 0.0029995 0.0 9009.6 10152.0 12401.0 11660.0 13602.0 14537.0 11339.0 17071.0 11986.0 9527.6 True False 10534.747332288707 11159.82346776935 12696.686871054402 11006.728002230042 10936.785742774 13774.654129074068 10264.8878327491 16622.904338219603 12161.272574715793 11254.878459559899 0.9360160902795435 0.991554329784005 1.1281051960423287 0.977951742595756 0.9717373476818214 1.223882974708969 0.9120389766652789 1.4769510304307285 1.0805334432008906 1.0 13.4582628568891 -6.974216893432334 1.388524704445695 1.171946657269856 1.0070825600451099 0.12244612890155371 0.15245667244342118 0.7497748415252334 2.954623233462143 0.07640098342683205 0.057306270838630824 1.0611654622717842e-07 6.974216893432334 -0.16486409722474615 T(ph)SSPSVEDATPALGVR ddPTM_PC-9_Lapatinib_30min_R1 1 TSSPSVEDATPALGVR 16 0 K7ER94;Q2V2M9-2;Q2V2M9;Q2V2M9-3;Q2V2M9-4;A0A0A0MTS9;K7EP24 K7ER94 FHOD3 FH1/FH2 domain-containing protein 3 1 T(0.729)S(0.001)S(0.263)PS(0.007)VEDATPALGVR 127.18 6.2377e-05 2962300.0 12588.0 9848.1 12666.0 9820.3 12673.0 14545.0 12826.0 11010.0 16204.0 9305.0 True False 12408.492811643524 9825.297329515464 11624.650372173905 10542.517621560457 11927.599056076633 13922.944256051032 13490.067521900013 11521.56479398109 14378.934884315375 10913.356851866865 1.1370005562972951 0.9003001975358961 1.0651764191313293 0.9660196917098911 1.0929358599720185 1.2757710065779935 1.2361061500149122 1.0557306015344108 1.3175538085566842 1.0 13.413807309684508 -6.530475384639352 7.1670573102424955 1.1845915581506479 1.0140444876302073 0.3352106616075293 0.10598089459936409 0.14230839436381748 42.66435616905124 0.032466965694227135 0.03354506520087811 2.947980560350998e-07 6.530475384639352 -0.1705470705204406 T(ph)SSTLDSEGTFNSYR ddPTM_PC-9_AZD4547_30min_R2 1 TSSTLDSEGTFNSYR 15 0 Q92609;Q92609-2;C9JNM0;C9JED7;F2Z3C3;C9K0P2;C9J397;C9JWX0;C9JW04;C9JDR8 Q92609 TBC1D5 TBC1 domain family member 5 1 T(0.868)S(0.129)S(0.002)T(0.002)LDSEGTFNSYR 266.07 3.283399999999999e-61 20935000.0 21733.0 28951.0 24676.0 20732.0 21627.0 24694.0 25796.0 31616.0 26872.0 23809.0 True False 28643.6419255178 38308.84458233828 24348.78011698803 15952.557706207013 18624.464359193666 23149.88027629896 28091.794026526357 26730.473663404307 28292.399059724692 22975.454156895576 1.2467062339623456 1.6673813854008508 1.0597736153859783 0.6943304622955279 0.8106244269214562 1.0075918464206304 1.222687213697372 1.1634361384487255 1.2314184897726321 1.0 14.487805759167141 -5.353246410056609 7.055902802241843 1.014649107476895 1.4547872726856215 0.46481349746656475 0.18610721946430994 0.21926412959473945 14.388796737009557 0.05366798406275756 0.11277709223927837 4.433570205942159e-06 5.353246410056609 0.4401381652087264 T(ph)SSTLDSEGTFNSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSSTLDSEGTFNSYR 15 0 Q92609;Q92609-2;C9JNM0;C9JED7;F2Z3C3;C9K0P2;C9J397;C9JWX0;C9JW04;C9JDR8 Q92609 TBC1D5 TBC1 domain family member 5 1 T(0.874)S(0.123)S(0.001)T(0.002)LDSEGTFNSYR;T(0.988)S(0.01)S(0.002)TLDSEGTFNSYR;T(0.871)S(0.128)STLDSEGTFNSYR 305.98 1.4073999999999995e-120 42042200.0 92627.0 187844.0 115027.0 87362.0 85648.0 56640.0 79815.0 59366.0 56144.0 55600.0 True False 108306.92163335861 206491.91090225268 117769.67992232656 82467.39037142564 68865.88922931226 53669.6986909786 72254.34538944095 57807.7054034764 56964.99978598733 65679.83987064208 1.6490131804016501 3.143916174414297 1.7930871962275878 1.2555967026388466 1.048508786942008 0.8171411318401852 1.1000992927471733 0.8801438236958247 0.8673133171180255 1.0 16.003162989337028 -5.679804441462227 2.554953533352237 0.9648822854230586 2.412809902316282 0.7191590547457538 0.3565236953894486 0.12740689555194334 1.6815481675387185 0.09617310328409097 0.18756326294914116 2.0902371322180326e-06 5.679804441462227 1.4479276168932231 T(ph)SSTLDSEGTFNSYR ddPTM_PC-9_Lapatinib_30min_R1 3 TSSTLDSEGTFNSYR 15 0 Q92609;Q92609-2;C9JNM0;C9JED7;F2Z3C3;C9K0P2;C9J397;C9JWX0;C9JW04;C9JDR8 Q92609 TBC1D5 TBC1 domain family member 5 1 T(0.886)S(0.114)STLDSEGTFNSYR;T(0.622)S(0.378)STLDSEGTFNSYR;T(0.922)S(0.078)STLDSEGTFNSYR 299.27 4.308299999999999e-104 47894000.0 44896.0 103288.0 88379.0 81610.0 98449.0 100769.0 105141.0 93089.0 85674.0 97417.0 True False 44255.774807081936 103048.8429819957 81112.81977280579 87611.87164297933 92658.42337818109 96459.34477401205 110584.68652113597 97414.25477810219 76024.49193278427 114255.39865000677 0.38734077627831476 0.9019166201297885 0.7099254891339962 0.7668072815653699 0.8109763256090622 0.8442432122572295 0.9678727467389517 0.8526008917662327 0.6653908071833572 1.0 16.80190280971211 -4.755597041381499 24.978928100958957 0.8284883239547501 0.38734005650436926 0.6436658681709682 0.09991738446372622 121.1098554871491 517753.01535396813 0.024646434216211988 0.2152281189294327 1.755508588931598e-05 4.755597041381499 -0.4411482674503809 T(ph)SSVSSISQVSPER ddPTM_PC-9_AZD4547_30min_R2 1 TSSVSSISQVSPER 14 0 P42356 P42356 PI4KA Phosphatidylinositol 4-kinase alpha 1 T(0.981)S(0.015)S(0.004)VSSISQVSPER 164.88 4.5856e-14 0.0 6493.9 9602.8 9696.4 18087.0 13031.0 10498.0 10858.0 15841.0 11093.0 12492.0 True False 8558.82511848893 12706.71730701108 9567.819400484788 13917.321591364374 11221.870581433051 9841.558400444897 11824.340965266827 13393.13743996671 11679.35333319166 12054.658882268872 0.7100014361317231 1.054091818865262 0.7937030399556174 1.1545180769764694 0.930915647720172 0.816411189778318 0.9808938669064441 1.111034129689609 0.968866348459744 1.0 13.557303206282338 -4.750812824903541 24.904205562151926 0.9755868202633933 0.7100008498327076 0.3559263607433111 0.1084476216393414 504.4468496552294 1182130.6239038985 0.026743236221386676 0.3776020058985665 1.7749542975600492e-05 4.750812824903541 -0.26558597043068566 T(ph)SSVSSISQVSPER ddPTM_PC-9_Lapatinib_30min_R1 1 TSSVSSISQVSPER 14 0 P42356 P42356 PI4KA Phosphatidylinositol 4-kinase alpha 1 T(0.908)S(0.026)S(0.065)VSSISQVSPER 112.62 0.0015902999999999998 0.0 7030.7 7525.8 9748.9 9142.7 9806.1 13475.0 11371.0 12367.0 10678.0 9912.2 True False 6930.440928727524 7508.374472483773 8947.38307384226 9815.084657153124 9229.324477534372 12898.705661759213 11959.734741269687 12941.615967953143 9475.331195675122 11625.51056282372 0.5961407794759416 0.6458533095737057 0.7696335593599108 0.8442712777312327 0.7938855182023646 1.1095173491138481 1.0287492043157878 1.113208396140303 0.8150464570541545 1.0 13.505006456654343 -5.845994692602125 0.8537635202840641 1.0167921992641802 0.5833036750990784 0.7085052671129841 0.09403963062227631 0.41208330442324176 0.5667476016348495 0.042817126092900615 0.12556868324231413 1.4256250156815856e-06 5.845994692602125 -0.43348852416510175 T(ph)SSVVTLEVAK ddPTM_PC-9_AZD4547_30min_R2 2 TSSVVTLEVAK 11 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 T(0.806)S(0.093)S(0.1)VVT(0.001)LEVAK;T(0.867)S(0.002)S(0.084)VVT(0.046)LEVAK 191.79 0.00080266 50143000.0 284820.0 297310.0 350660.0 522140.0 422760.0 385410.0 364110.0 407740.0 365610.0 379520.0 True False 375386.83537597145 393409.6432860695 346010.0192828261 401768.6899825836 364067.07136878476 361310.2517732395 396515.0846254653 344733.151933087 384935.3981923918 366233.1203168978 1.0249942305904858 1.0742055304710183 0.9447807969509343 1.097029918088613 0.9940856005971311 0.9865581011913981 1.0826849419909503 0.9412943090313428 1.051066593483711 1.0 18.482402741695132 -1.5228787530817114 0.18850529685514372 1.0019858697974762 1.1670011881652913 0.02544040019830962 0.052081276043950894 233.2551611384034 2.7120063031549573 0.10239353559805753 11.16995941264067 0.029999999461100192 1.5228787530817114 0.16501531836781513 T(ph)SSVVTLEVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSVVTLEVAK 11 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 T(0.654)S(0.005)S(0.341)VVTLEVAK 209.19 7.8678e-06 39137000.0 111780.0 103670.0 105800.0 123880.0 129530.0 107990.0 119680.0 105120.0 108580.0 89712.0 True False 130702.14624436521 113961.6724688384 108322.67324873459 116939.40522437905 104149.52633888506 102326.81429446996 108343.04399183433 102360.71138384682 110167.77708682133 105976.07544019863 1.2333174794543065 1.0753528284140506 1.0221427128603202 1.1034509887127018 0.9827645145970302 0.9655652360160486 1.022334933066769 0.9658850920706916 1.0395532824669285 1.0 16.69337908130511 -1.5228787553694407 0.7228575872578747 1.0009485846489539 34.161677068771645 0.771053376912328 0.036808222638821116 150.3365321604587 0.7267838587424741 0.014219119155901136 8087.056635940049 0.02999999930306945 1.5228787553694407 33.16072848412269 T(ph)STFCGTPEFLAPEVLTDTSYTR ddPTM_PC-9_AZD4547_30min_R2 1 TSTFCGTPEFLAPEVLTDTSYTR 23 0 Q16512;Q16512-2 Q16512 PKN1 Serine/threonine-protein kinase N1 1 T(0.333)S(0.333)T(0.333)FCGT(0.001)PEFLAPEVLTDTSYTR 106.36 4.4941e-06 3076800.0 8193.9 8223.0 13368.0 14822.0 11934.0 11116.0 10860.0 9395.9 9173.8 9185.8 True False 10799.389756292278 10880.923940470708 13190.731585503963 11405.016897617237 10277.170095834705 10420.91476274963 11826.518961392316 7943.979551302524 9658.708339316114 8864.207937939911 1.2183141270941478 1.2275122624209887 1.4880891420705502 1.2866368859424369 1.159400836237961 1.1756171375613629 1.3341878985908426 0.8961860559815282 1.089630162890882 1.0 13.113776009406147 -7.7571456386795825 24.999997270138557 0.994681063447933 1.2694819818577154 0.6219340572463716 0.09814443218161746 72.67209201438042 423135.6660405761 0.05057970508156726 0.027879769963269588 1.7492599838748152e-08 7.7571456386795825 0.2748009184097825 T(ph)STFCGTPEFLAPEVLTDTSYTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSTFCGTPEFLAPEVLTDTSYTR 23 0 Q16512;Q16512-2 Q16512 PKN1 Serine/threonine-protein kinase N1 1 T(0.311)S(0.311)T(0.311)FCGT(0.067)PEFLAPEVLTDTSYTR;T(0.331)S(0.331)T(0.331)FCGT(0.008)PEFLAPEVLTDTSYTR 116.83 5.7526e-08 5525700.0 19375.1 18177.1 20769.0 21770.3 18175.2 19732.8 22516.5 19088.2 22253.7 14828.5 True False 22654.921754331695 19981.602359731118 21264.211726871126 20550.580671264906 14613.900031764888 18697.97723039092 20383.574114656964 18587.154975619687 22579.118262635813 17516.789667658595 1.2933261279125638 1.1407114396437223 1.2139331538661693 1.1731933225873932 0.8342795859875318 1.067431737501145 1.1636592378734407 1.0611051070583624 1.2889986516378535 1.0 14.096450773498985 -6.020008176644913 24.828523760672244 1.0702769100335165 1.2059792246895424 0.2603333347812964 0.11368284289162282 1045.668452150379 1297590.1026470053 0.034058867565362576 0.044582098034245767 9.549746061435242e-07 6.020008176644913 0.1357023146560259 T(ph)STFCGTPEFLAPEVLTDTSYTR ddPTM_PC-9_Lapatinib_30min_R1 3 TSTFCGTPEFLAPEVLTDTSYTR 23 0 Q16512;Q16512-2 Q16512 PKN1 Serine/threonine-protein kinase N1 1 T(0.331)S(0.331)T(0.331)FCGT(0.007)PEFLAPEVLTDTSYTR;T(0.333)S(0.333)T(0.333)FCGT(0.001)PEFLAPEVLTDTSYTR;T(0.332)S(0.332)T(0.332)FCGT(0.005)PEFLAPEVLTDTSYTR 116.83 1.6503000000000001e-06 3009000.0 13793.2 16549.3 15076.1 13989.4 15452.4 15836.9 16498.699999999997 14264.099999999999 15586.400000000001 8914.5 True False 13596.506438636916 16510.981112635953 13836.601253428933 15018.227143270358 14543.520212587277 15159.59270461703 17352.921957240906 14926.862159657192 13830.895499931708 10455.359447175399 1.3004341464616145 1.5791882810013318 1.3233979494762378 1.436414235124901 1.3910110203352528 1.4499351056469436 1.6597154832327587 1.4276756562099648 1.3228522242406728 1.0 13.351955041069791 -8.67094898032065 2.400492982401056 1.0006251094701817 1.450819137428501 0.6371265127419155 0.10165290726209997 0.35998022018297726 4.084830558733897 0.09706782046511644 0.026344998794699915 2.133295511909975e-09 8.67094898032065 0.4501940279583194 T(ph)STFCGTPEFLAPEVLTETSYTR ddPTM_PC-9_AZD4547_30min_R2 2 TSTFCGTPEFLAPEVLTETSYTR 23 0 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5;H0Y429 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 T(0.649)S(0.163)T(0.163)FCGT(0.025)PEFLAPEVLTETSYTR;T(0.689)S(0.162)T(0.137)FCGT(0.012)PEFLAPEVLTETSYTR 98.23 1.5394000000000002e-05 5633000.0 13583.2 11232.4 14108.3 18695.5 7108.6 12622.0 15241.5 8588.0 9080.4 8838.7 True False 17902.375051888514 14863.053638446218 13921.214723800536 14385.541317595667 6121.693593367738 11832.74434467666 16597.96397330212 7260.921932607418 9560.371405995988 8529.2598032909 2.0989365390160963 1.7425959557137076 1.6321714949319777 1.6866107551378842 0.7177285877733217 1.3873119845770383 1.9460028602831418 0.8512956692684972 1.1208911003399435 1.0 13.058204829903529 -1.522878745544752 0.2994704795582459 1.091254413948618 9.69033351570474 0.45263191277682435 0.3342681507804482 54.3941636435003 0.7750205237602991 0.357810395041814 250.4183028572772 0.02999999998173489 1.522878745544752 8.599079101756121 T(ph)STGSASSSAAVAASSK ddPTM_PC-9_AZD4547_30min_R2 2 TSTGSASSSAAVAASSK 17 0 Q9UDT6-2;Q9UDT6 Q9UDT6-2 CLIP2 CAP-Gly domain-containing linker protein 2 1 T(0.977)S(0.019)T(0.004)GSASSSAAVAASSK;T(0.967)S(0.033)TGSASSSAAVAASSK 191.36 1.7569999999999998e-08 8558400.0 15697.3 19581.5 27195.0 43762.0 45359.0 45569.0 33195.0 46388.0 34069.0 46345.0 True False 20688.714875876787 25910.83693789703 26834.376531102655 33673.347016160136 39061.68580333218 42719.563226316815 36149.2906927641 39219.8004901948 35869.81778675801 44722.47565632015 0.46260218318108853 0.5793694682068731 0.6000199259387475 0.7529401385319204 0.8734240497666189 0.9552146342390532 0.8083025405516768 0.8769595134130792 0.8020534923515333 1.0 15.448712431734108 -5.7910277798714525 1.522475328717269 0.8821280794547312 0.5108797589353745 0.8625806540008419 0.06111980454886932 0.1397530514836448 0.6564280113937688 0.01982780099255307 0.04333889466118499 1.6179765396256553e-06 5.7910277798714525 -0.37124832051935663 T(ph)STSDLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSTSDLSR 8 0 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 T(0.824)S(0.157)T(0.009)S(0.009)DLSR 74.165 0.040037 0.0 16222.0 18397.0 30074.0 24307.0 27773.0 27746.0 19832.0 22075.0 20825.0 27076.0 True False 18968.06420089541 20223.332578462643 30791.078216280133 22945.157594357268 22331.080020148675 26290.950915958532 17953.369388753887 21495.554640395872 21129.52622797067 31984.664466501927 0.5930362102363456 0.6322821550822544 0.9626825458346809 0.7173799687155735 0.6981808436207416 0.8219861409987116 0.5613117938928748 0.6720581565865268 0.6606142843893196 1.0 14.965092728373243 -10.729676539837278 4.084486049091057 1.0001674660356226 0.7066022912414192 0.3951727638202228 0.11041551917377473 163701944.00301382 253131737.65198442 336279.8096154548 0.028418249088425065 1.863474525607484e-11 10.729676539837278 -0.2935651747942034 T(ph)STSDLSR ddPTM_PC-9_Lapatinib_30min_R1 2 TSTSDLSR 8 0 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 T(0.99)S(0.009)TSDLSR;T(0.703)S(0.292)T(0.002)S(0.003)DLSR 145.9 0.0032804 18140200.0 185530.0 143624.0 130955.0 129009.0 133964.0 125743.0 110005.0 111497.0 134345.0 104993.0 True False 182884.30817796526 143291.4474522324 120188.3854009185 138496.7522214081 126084.50090335752 120365.26501124968 115700.52064140113 116677.5576598103 119213.65138443279 123140.90015562165 1.485162995778346 1.163638135429781 0.9760232810465747 1.1247014764905907 1.0239043302754474 0.9774596812199341 0.9395783244655708 0.9475126258810584 0.9681076818000702 1.0 16.90995049419068 -1.5228787484930344 0.8237867381590441 0.9791971344990762 150.97769130552555 0.902768113080566 0.0493084286077041 169.4946520829504 0.5306576165299336 0.018534209748333384 47547.78852325906 0.029999999778074767 1.5228787484930344 149.99849417102646 T(ph)STSSSSVQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSTSSSSVQAR 11 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 T(0.945)S(0.054)TSSSSVQAR;T(0.996)S(0.004)TSSSSVQAR 100.04 0.010546999999999999 5059600.0 18240.8 21503.0 26993.0 27556.0 30145.0 25833.0 29590.0 23831.0 24781.0 17798.2 True False 21328.607167777904 23637.675731623745 27636.61549152255 26012.12665775737 24238.303647693156 24478.272003602568 26787.020986951746 23205.461501031677 25143.375243953975 21024.87276952633 1.0144464321654212 1.1242719987292593 1.3144724248500257 1.2372073278588214 1.1528394922239151 1.1642530383861172 1.2740634048343509 1.1037147171071549 1.1958871532576905 1.0 14.359809449693184 -9.896922312133755 0.8965011992118571 0.9937090450711202 1.181354196114532 0.2871608033685611 0.08245869021816288 24.82807866464895 14.04700112779587 0.6608913544614672 0.027216779212928952 1.2678786474116726e-10 9.896922312133755 0.18764515104341173 T(ph)STSSSSVQAR ddPTM_PC-9_Lapatinib_30min_R1 1 TSTSSSSVQAR 11 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 T(0.884)S(0.115)T(0.001)SSSSVQAR 84.605 0.029138 3174600.0 12264.0 13340.0 16298.0 16770.0 12394.0 16748.0 12223.0 9966.0 14613.0 9719.4 True False 12089.113111057844 13309.11204960715 14958.041352099333 18003.321743080036 11665.009287541525 16031.727081494864 12855.847132401683 10429.056742671717 12967.130058288123 11399.385339713564 1.0605056984029992 1.1675289195848495 1.3121796400712942 1.57932390269846 1.0233016026664674 1.406367677180189 1.1277666952457557 0.9148788668752705 1.137528881764598 1.0 13.476668415232966 -7.518581625134962 21.408102290044067 1.019986587785112 1.261003830287431 0.315885602709877 0.15993122789308484 34.80892426947437 173438.811803191 0.07318163646385954 0.04384902339399805 3.029830791152095e-08 7.518581625134962 0.24101724250231893 T(ph)SVAGATEK ddPTM_PC-9_Lapatinib_30min_R1 1 TSVAGATEK 9 0 Q5JTC6;Q5JTC6-2 Q5JTC6 AMER1 APC membrane recruitment protein 1 1 T(0.5)S(0.5)VAGATEK 82.671 0.037739 6842100.0 16070.0 14298.0 16712.0 12406.0 15600.0 18038.0 13486.0 12045.0 17303.0 11771.0 True False 15840.838853122923 14264.893859466496 15338.00387018555 13318.378625202795 14682.438670780039 17266.556788631726 14184.239092495205 12604.65467243436 15354.153931332326 13805.601666128403 1.147421114719535 1.0332685387022973 1.110998581671152 0.9647083080688186 1.0635131322673843 1.2506920890666189 1.0274263618148405 0.9130101662544323 1.1121684011065773 1.0 13.752966143377257 -7.507443008184601 24.940353353306243 1.0015972101051205 1.0901005111048663 0.18864596852630833 0.08321550693537254 1136.8192044666387 1836827.9193272344 0.03602092798424187 0.023421719916080566 3.108543805529615e-08 7.507443008184601 0.0885033009997458 T(ph)SVAGTVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSVAGTVR 8 0 Q96EB6;B0QZ35;E9PC49 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 T(0.984)S(0.016)VAGTVR 101.46 0.011196 3830900.0 25357.0 26849.0 25978.0 34640.0 27720.0 27564.0 31837.0 20402.0 21994.0 24083.0 True False 29649.43927642122 29514.391281140593 26597.414042113625 32699.23310439527 22288.464989684984 26118.49531635124 28821.168880080524 19866.46911770584 22315.620641439964 28449.05725907691 1.0421940877130935 1.037447076448334 0.9349137231472757 1.1493960171197695 0.7834517954922271 0.918079466693678 1.0130799280136036 0.6983173093149607 0.7844063315778232 1.0 14.796093225044768 -6.269380154674716 24.970436910896748 0.8610740601495882 1.0331581097323583 0.4045191720284743 0.10359150943442394 633.082365689582 1990778.0276206424 0.03251206168726291 0.03754015627696859 5.377988204149436e-07 6.269380154674716 0.17208404958277013 T(ph)SVAGTVR ddPTM_PC-9_Lapatinib_30min_R1 1 TSVAGTVR 8 0 Q96EB6;B0QZ35;E9PC49 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 T(0.904)S(0.096)VAGTVR 91.265 0.02165 3774200.0 25273.0 31690.0 30164.0 31593.0 29961.0 34415.0 29645.0 27513.0 32169.0 23997.0 True False 24912.60238549943 31616.62375202781 27684.032356407184 33916.454611158464 28198.752885592363 32943.15067528334 31179.87304590099 28791.35442114457 28545.788465412348 28144.84947600743 0.8851567107060428 1.1233538050711536 0.9836269467352071 1.2050678984824963 1.0019152139943361 1.1704859428495542 1.1078358430191932 1.0229706307609945 1.0142455545817257 1.0 14.780583311969131 -4.752239349995191 24.99883273309758 1.0743877497532544 0.8851563434247468 0.35666291057745747 0.07423796754382994 386.98295495049695 1051456.058127984 0.017501302399024022 0.2128416396443328 1.769133678038889e-05 4.752239349995191 -0.18923140632850755 T(ph)SVPSPEQPQPYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSVPSPEQPQPYR 13 0 Q8TEH3 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 T(0.655)S(0.016)VPS(0.329)PEQPQPYR 84.169 0.021324 10519000.0 27648.0 31166.0 33298.0 32810.0 31283.0 30232.0 26505.0 22140.0 24231.0 21885.0 True False 32328.26032710865 34259.95451108153 34091.95060336823 30971.762071455207 25153.320716894505 28646.58069960564 23994.254520417588 21558.84845926905 24585.332534451725 25852.577258435314 1.2504850098285816 1.3252046079817057 1.3187060718383319 1.198014486596286 0.9729521534912867 1.108074464423414 0.9281184726984469 0.8339148644158763 0.9509818804014943 1.0 14.658020490365207 -6.2818698277255605 1.138599163760989 0.9298962702094606 1.316520840432554 0.8316894698359671 0.06843666936095645 0.1878831490517219 0.5050777296647948 0.030227816058838272 0.04398339489823454 5.225527917078135e-07 6.2818698277255605 0.38662457022309327 T(ph)SVSPAPDKTK ddPTM_PC-9_Lapatinib_30min_R1 1 TSVSPAPDKTK 11 1 O75362 O75362 ZNF217 Zinc finger protein 217 1 T(0.775)S(0.058)VS(0.167)PAPDKTK 118.76 0.0056607 0.0 9164.0 9341.7 13180.0 9278.7 12441.0 12528.0 7056.2 9332.9 10034.0 8017.6 True False 9033.31967952822 9320.069867602333 12096.391276271286 9961.08655083583 11709.244839947089 11992.206644194388 7421.535509748239 9766.540605426537 8903.865257295762 9403.43147721953 0.9606407726171099 0.991134979840163 1.2863805415688558 1.0593033590947365 1.245209779888709 1.275301114624629 0.7892369426764503 1.0386145343948816 0.9468740511233582 1.0 13.198971602280208 -7.25772364847863 24.998145877638283 0.9468992626363917 1.1379972825610865 0.37608486933741625 0.12151949427037667 373.29184108337296 2511386.63212271 0.049311939350547354 0.036704821224721504 5.524288505880469e-08 7.25772364847863 0.19109801992469477 T(ph)SWPPATAR ddPTM_PC-9_AZD4547_30min_R2 1 TSWPPATAR 9 0 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 T(0.996)S(0.004)WPPATAR 83.081 0.036279 6085700.0 47928.0 49212.0 68579.0 80201.0 63844.0 61727.0 52534.0 60583.0 56679.0 67407.0 True False 63168.107035669986 65118.81660688861 67669.59765127748 61711.89854309801 54980.36262765806 57867.20093201204 57209.424228156946 51221.28940884432 59674.936227528124 65047.10144709394 0.9711133260418646 1.0011025112295435 1.040316880319664 0.9487263409160727 0.8452392405582644 0.8896199775954403 0.8795076637609783 0.7874492217075215 0.9174111513034094 1.0 15.989197150234679 -6.035725742531857 4.430911219466621 0.8763660414878878 1.0034700490924373 0.48986417314077335 0.05343525946731592 0.15366879456596463 6.935122085806451 0.015200466181859246 0.02094887708900315 9.21031020296811e-07 6.035725742531857 0.12710400760454954 T(ph)SWPPATAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSWPPATAR 9 0 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 T(0.998)S(0.002)WPPATAR 131.42 0.0030180999999999997 4370400.0 31414.0 26521.0 30360.0 40977.0 39279.0 35444.0 34271.0 34554.0 29066.0 27994.0 True False 36731.76974521813 29153.829608817072 31083.89754094116 38681.19153922644 31582.561916660772 33585.25424440402 31024.60277944656 33646.994112989305 29491.035262530408 33069.09059961793 1.1107583873395817 0.8816036086929439 0.9399683201841752 1.1697083541714737 0.9550477906708952 1.0156086434621234 0.9381752632715279 1.0174756397255766 0.8918006128318249 1.0 15.013195751493322 -7.246194832908299 23.137162923181705 0.9633191806444749 1.007473339711322 0.07778017296168693 0.08380230796690656 995.5427470465199 1510969.8912676584 0.03206084003374824 0.02470735131104468 5.6729005101969905e-08 7.246194832908299 0.044154159066847165 T(ph)T(ph)IINNT(ph)PY(ph)QIFYK ddPTM_PC-9_Lapatinib_30min_R1 1 TTIINNTPYQIFYK 14 0 Q7Z7G8-2;Q7Z7G8-6;Q7Z7G8 Q7Z7G8-2 VPS13B Vacuolar protein sorting-associated protein 13B 4 T(1)T(1)IINNT(1)PY(0.962)QIFY(0.038)K 47.223 0.044662 0.0 17465.0 22285.0 19831.0 21317.0 20799.0 21317.0 18690.0 15927.0 19753.0 19502.0 True False 17215.945897311263 22233.400451686306 18200.57172987374 22884.723291427388 19575.643712407327 20405.32160235407 19657.67674912765 16667.026564372107 17528.209131688585 22872.894715218434 0.7526789289969786 0.9720413934705587 0.7957266431066998 1.0005171438226874 0.855844612417278 0.8921180225071133 0.8594310861776694 0.7286802467237666 0.7663310372353626 1.0 14.48135133939685 -7.53712940869125 24.701168026980312 0.8073144955008486 0.8826024730236112 0.025724992535255953 0.0959833050896774 454.18498463603026 787243.1312517748 0.04197148885617656 0.02424680828849659 2.903157458607677e-08 7.53712940869125 0.07528797752276262 T(ph)T(ph)MLQK ddPTM_PC-9_AZD4547_30min_R2 1 TTMLQK 6 0 A0A5F9ZHF7;A0A5F9ZI46;A0A5F9ZHT4;A0A5F9ZI30;A0A5F9ZHE4;D6RHE1;A0A5F9ZH30;A0A5F9ZHD2;A0A5F9ZGY3;A0A5F9ZGY4;A0A5F9ZI40;A0A5F9ZHN5;A0A5F9ZH19;A0A5F9ZI65;B7Z651;A0A5F9ZGZ1;A0A5F9ZHQ5;A0A5F9ZHG3;A0A5F9ZHC9;A0A5F9ZI45;A0A5F9ZI56;A0A5F9ZI18;A0A5F9ZHL5;A0A5F9ZHR2;A0A5F9ZH34;A0A5F9ZH38;A0A5F9ZI53;A0A5F9ZH35;A0A5F9ZHY6;A0A5F9ZI15;A0A5F9ZH58;A0A5F9ZHN0;A0A5F9ZH03;A0A5F9ZI08;A0A5F9ZHL9;A0A5F9ZGS5;A0A5F9ZHJ4;A0A5F9ZI73;A0A5F9ZGS7;A0A5F9ZGX8;A0A5F9ZHQ3;A0A5F9ZI36;A0A5F9ZHA1;A0A5F9ZHJ6;A0A5F9ZHL3;Q01484-5 A0A5F9ZHF7 ANK2 Ankyrin-2 2 T(1)T(1)MLQK 47.067 0.044757 0.0 2140.2 2191.8 4001.2 5991.0 5273.3 3228.5 3169.4 3961.7 2067.3 3630.8 True False 2820.7390810745474 2900.256487014922 3948.1414736623633 4609.867510027309 4541.193318783741 3026.621384629109 3451.4704600586388 3349.5102958093617 2176.5732575234024 3503.686797129508 0.8050774068576894 0.8277727590808166 1.126853426766624 1.3157190630749502 1.2961185122209666 0.8638390243981717 0.9850967452017547 0.9559959236520629 0.6212236947967553 1.0 11.774658099434593 -7.584265165419713 1.5280721582363335 0.8287696863978342 1.0610422663031904 0.16455280560626506 0.18979910482701381 0.766780336662572 3.4364362784390265 0.14804806128576997 0.06694476778640716 2.6045628070762023e-08 7.584265165419713 0.2322725799053562 T(ph)T(ph)S(ph)NFS(ph)GKGY(ph)IIQKREIK ddPTM_PC-9_AZD4547_30min_R2 1 TTSNFSGKGYIIQKREIK 18 3 G3V5V3;O60524-4;O60524-3;O60524 G3V5V3 NEMF Nuclear export mediator factor NEMF 5 T(1)T(1)S(1)NFS(1)GKGY(1)IIQKREIK 42.647 0.046004 0.0 10137.0 6864.5 9350.0 13058.0 12925.0 11836.0 9854.5 9825.8 8618.1 8972.0 True False 13360.355137301516 9083.31538238614 9226.012890818525 10047.679844088912 11130.586851739867 11095.89304892988 10731.531409303927 8307.448384421752 9073.635171800144 8657.893010864256 1.5431416304794285 1.0491369402449358 1.0656187226200844 1.1605225233761491 1.2855999534497342 1.2815927657001915 1.2395084341926599 0.95952310498608 1.0480188609877945 1.0 13.079800257348037 -7.757628119304667 24.99422865290578 1.002828212856796 1.2199167044127155 0.3874885811970501 0.13168266099065806 107.11414904729813 702468.6823138305 0.06565530009258475 0.03606096516005376 1.7473177178641062e-08 7.757628119304667 0.21708849155591947 T(ph)T(ph)VLRLLETKY(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 TTVLRLLETKYK 12 2 Q96NH3;Q96NH3-4 Q96NH3 TBC1D32 Protein broad-minded 3 T(0.998)T(0.998)VLRLLET(0.02)KY(0.983)K 54.25899999999999 0.045086 5815500.0 14760.0 12097.0 16312.0 13846.0 16804.0 18944.0 18835.0 15589.0 18707.0 12326.0 True False 14549.519693347496 12068.990139737467 14970.8903261409 14864.281028901989 15815.621757935127 18133.809280620877 19810.18413963721 16313.321850442428 16600.0206665569 14456.532676637396 1.0064321797480784 0.8348468066095587 1.0355795999641557 1.0282051278397855 1.0940121059245485 1.254367813239628 1.3703274901907585 1.1284394546975784 1.148271237499674 1.0 13.819433950506603 -6.137964172801866 1.5069152840506488 1.1963175927466094 0.9380882058495553 0.4684746586181857 0.10244661097984668 0.32397543890104535 1.4732590400735557 0.03741511427195551 0.05718921087571632 7.278398453337334e-07 6.137964172801866 -0.2582293868970541 T(ph)TAGSVDWTDQLGLR ddPTM_PC-9_AZD4547_30min_R2 1 TTAGSVDWTDQLGLR 15 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 T(0.928)T(0.015)AGS(0.055)VDWT(0.001)DQLGLR 184.51 1.1727e-06 9284000.0 17199.0 21427.0 30638.0 47927.0 41567.0 37452.0 28310.0 38641.0 32665.0 39841.0 True False 22667.92423857637 28352.858722177552 30231.720101486408 36878.17061476868 35796.139548647654 35110.120519476346 30829.535156263028 32669.921331844824 34391.605213080824 38446.1787166566 0.5896014895429805 0.7374688374398528 0.7863387496658719 0.9592155019242891 0.9310714547851584 0.9132278341167123 0.801888150795759 0.8497573080700153 0.8945389726906942 1.0 15.230552590987667 -5.061102276169258 1.4738589080158264 0.8961017160522068 0.5595736182490247 0.7529245322790417 0.057471806393883496 0.3686443379489694 1.0729354858513702 0.017660508071827334 0.15666665037510644 8.687558135622246e-06 5.061102276169258 -0.33652809780318205 T(ph)TFSPPVVAATVK ddPTM_PC-9_AZD4547_30min_R2 1 TTFSPPVVAATVK 13 0 A0A1B0GV05;Q684P5-3;Q684P5-2;Q684P5 A0A1B0GV05 RAP1GAP2 Rap1 GTPase-activating protein 2 1 T(0.695)T(0.001)FS(0.304)PPVVAATVK 151.99 0.00033487 7953000.0 56430.0 41259.0 59383.0 81743.0 71339.0 69752.0 49258.0 62672.0 58103.0 61298.0 True False 74373.56618308408 54595.164886280065 58595.54261983704 62898.41426676058 61434.81125077532 65390.396413396134 53641.866574609834 52987.48245928881 61174.20596037451 59151.97567765911 1.2573302130832118 0.9229643517536796 0.9905931619113743 1.063335815011779 1.0385927189576256 1.1054642835555057 0.9068482660143782 0.895785505931993 1.0341870285742487 1.0 15.852138734974371 -7.264694702310618 24.991605946285617 0.9505206587366304 1.0522876219136967 0.2371059465570261 0.08947739174142567 443.8750272612633 3407676.525633477 0.03564550912496214 0.025159649161497075 5.4363235656235044e-08 7.264694702310618 0.10176696317706635 T(ph)TFSPPVVAATVK ddPTM_PC-9_Lapatinib_30min_R1 1 TTFSPPVVAATVK 13 0 A0A1B0GV05;Q684P5-3;Q684P5-2;Q684P5 A0A1B0GV05 RAP1GAP2 Rap1 GTPase-activating protein 2 1 T(0.973)T(0.013)FS(0.014)PPVVAATVK 201.09 7.0256e-07 8645700.0 62641.0 51398.0 59120.0 48237.0 53977.0 49096.0 44470.0 43462.0 58057.0 41902.0 True False 61747.72785304748 51278.9910888837 54259.38180979952 51784.50989391486 50802.178982865065 46996.27852836584 46772.43900661887 45481.40318583162 51518.00929268688 49144.704869094596 1.2564472208658737 1.0434286099687473 1.104073815364824 1.0537149430819015 1.0337264028380155 0.9562836658302972 0.9517289630938945 0.9254588730765438 1.0482921696226275 1.0 15.584748360293698 -1.5228787452806887 0.45917671718622854 0.9730387077712168 7.100358768206851 0.7220779211693158 0.0473616573355491 48.60389601474782 0.5732880383644611 0.029267886004265574 280.8218410910612 0.029999999999975747 1.5228787452806887 6.127320060435634 T(ph)TGTPPDSSLVTYELHSRPEQDK ddPTM_PC-9_AZD4547_30min_R2 1 TTGTPPDSSLVTYELHSRPEQDK 23 1 F8VW18;F8W1I6;Q13561;Q13561-3;Q13561-2;H0YI98 F8VW18 DCTN2 Dynactin subunit 2 1 T(0.33)T(0.33)GT(0.33)PPDS(0.007)S(0.003)LVT(0.001)YELHSRPEQDK 45.571999999999996 0.035559 2212500.0 14874.0 16668.0 18249.0 22114.0 22022.0 20389.0 16473.0 22650.0 18650.0 22046.0 True False 19603.622601580628 22055.605039494803 18007.00633631522 17015.958957894185 18964.625427389972 19114.072606846166 17939.065087570514 19149.962945221014 19635.80092527038 21274.17625028015 0.9214750489491914 1.036731330041715 0.8464255501351359 0.7998410259325603 0.8914387661491822 0.898463582419294 0.8432319482797499 0.9001506201664958 0.9229876021644695 1.0 14.376815650466861 -10.447272771712282 11.810049390018563 1.0000000104431621 0.8940740954658081 0.21487178170808197 0.059779767148503755 0.0 0.0 0.06207632451233025 0.015055720389903968 3.5704851265426263e-11 10.447272771712282 -0.10592591497735404 T(ph)TIFSPEGR ddPTM_PC-9_AZD4547_30min_R2 1 TTIFSPEGR 9 0 P25789;H0YMI6;H0YMA1;H0YMZ1;H0YL69;H0YLS6;H0YLC2 P25789 PSMA4 Proteasome subunit alpha type-4;Proteasome subunit alpha type 1 T(0.864)T(0.011)IFS(0.125)PEGR 105.17 0.006490300000000001 4378300.0 18942.0 23984.0 27330.0 36539.0 30424.0 27407.0 27641.0 37139.0 24931.0 27418.0 True False 24965.16198192418 31736.358967317232 26967.586342895225 28115.498071922553 26200.152756466836 25693.235957419827 30100.99545228777 31400.020919318442 26248.801762354728 26458.104165389694 0.9435733499976745 1.1994948227935438 1.019256186094089 1.0626422020327868 0.9902505709664455 0.9710913448980065 1.1376852726909816 1.1867827234724306 0.9920892894771819 1.0 14.691422069692894 -7.276846864800325 24.951398723905616 1.0947045422293582 1.0377531415160184 0.05611609018681063 0.08515672386065408 2112.70898763516 3421377.6547926324 0.035104553118854194 0.023778930980984332 5.286316180342495e-08 7.276846864800325 -0.05695140071333982 T(ph)TIFSPEGR ddPTM_PC-9_Lapatinib_30min_R1 2 TTIFSPEGR 9 0 P25789;H0YMI6;H0YMA1;H0YMZ1;H0YL69;H0YLS6;H0YLC2 P25789 PSMA4 Proteasome subunit alpha type-4;Proteasome subunit alpha type 1 T(0.783)T(0.012)IFS(0.204)PEGR;T(0.972)T(0.017)IFS(0.012)PEGR 96.171 0.012691 7888200.0 50335.0 44548.0 62060.0 50970.0 46088.0 47199.0 39032.0 38062.0 53727.0 37259.0 True False 49617.21366969153 44444.85184302099 56957.66635852772 54718.5038309356 43377.19445249428 45180.4087962429 41052.88597495721 39830.49947216242 47675.69948960826 43699.16850550322 1.1354269512803894 1.017064016616789 1.3034038931737293 1.2521635010983028 0.9926320325072457 1.0338963037832891 0.9394431834506701 0.9114704200183212 1.090997863806133 1.0 15.415318208373728 -6.278412470047596 23.899948213438826 0.9895064375012417 1.1746173489879246 0.5321254956802465 0.0836332037294321 381.657050946611 537412.8885597559 0.02746935990702041 0.031238675411363145 5.267293639524522e-07 6.278412470047596 0.1851109114866829 T(ph)TKSPSDSGYSYETIGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTKSPSDSGYSYETIGK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.382)T(0.378)KS(0.089)PS(0.06)DS(0.089)GY(0.001)S(0.002)YETIGK;T(0.276)T(0.276)KS(0.276)PS(0.111)DS(0.059)GY(0.001)S(0.002)YETIGK 74.742 0.006788600000000001 501410000.0 81235.0 67386.0 84906.0 102833.0 99862.0 91991.0 100218.0 104058.0 80213.0 62487.0 True False 94986.4810356147 74075.63674144052 86930.48104779824 97071.60039908424 80294.75796536524 87166.83001909981 90724.62552451256 101326.5877585646 81385.96337691294 73815.39845318013 1.2868111942234255 1.0035255284630817 1.1776740743726635 1.3150589502088124 1.0877778843975876 1.180875966880925 1.2290745213826582 1.3727025780783986 1.1025607811158087 1.0 16.17163418438176 -5.510964565660352 24.789099546915967 1.201050614377413 1.1315262256204546 0.0 0.1212866691559026 1612.1577353545233 3354311.168644601 0.030872428631416895 0.0591153196493045 3.0834395196121192e-06 5.510964565660352 -0.06952438875695832 T(ph)TKSPSDSGYSYETIGK ddPTM_PC-9_Lapatinib_30min_R1 1 TTKSPSDSGYSYETIGK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.302)T(0.302)KS(0.302)PS(0.087)DS(0.003)GY(0.003)S(0.001)YETIGK 54.008 0.041466 355930000.0 30658.0 23332.0 26582.0 26351.0 30209.0 24859.0 19525.0 21589.0 23835.0 15721.0 True False 30220.81129801138 23277.976187513817 24396.530569487335 28288.940444359097 28432.16601317912 23795.83851915935 20535.90896344129 22592.103754519332 21150.45130632295 18438.353903084248 1.6390189415420777 1.2624758321630885 1.323140378892849 1.5342443578776903 1.542012164568724 1.290561979894471 1.1137604295579866 1.2252776941622903 1.1470899960752483 1.0 14.170422243458745 -7.01373739885177 3.994548967369886 1.143572051654435 1.445259532299704 0.6549059964768145 0.11503390864105441 0.15580063147762435 5.646169589422784 0.045303475260156253 0.03680670743699075 9.688635136362754e-08 7.01373739885177 0.30168748064526896 T(ph)TKTPEDGDYSYEIIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TTKTPEDGDYSYEIIEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.372)T(0.372)KT(0.256)PEDGDYSYEIIEK;T(0.704)T(0.148)KT(0.148)PEDGDYSYEIIEK;T(0.49)T(0.099)KT(0.411)PEDGDYSYEIIEK 105.46 0.00051952 35719300.0 95978.0 88433.0 83684.0 115822.0 122284.0 103092.0 124496.0 120567.0 105963.0 80933.0 True False 112225.17974809134 97212.04380666355 85679.34393333714 109332.86883999038 98323.32802303914 97685.67403690609 112702.83760701388 117402.24400129626 107512.50841269924 95605.51223472459 1.1738358712263701 1.0168037546621236 0.8961757740807104 1.1435833173673422 1.0284273963371686 1.0217577601286671 1.1788320042709777 1.2279861407264647 1.1245429881568056 1.0 16.544806180228726 -7.259315699267518 24.729020444782716 1.1518391305155955 1.042124628033271 0.16758194999577736 0.08972933865532742 233.2043223777511 2715545.527636213 0.03514443891285711 0.025830802786137714 5.504074463295697e-08 7.259315699267518 -0.1097145024823245 T(ph)TKTPEDGDYSYEIIEK ddPTM_PC-9_Lapatinib_30min_R1 1 TTKTPEDGDYSYEIIEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.627)T(0.223)KT(0.15)PEDGDYSYEIIEK 71.309 0.009762999999999999 16896000.0 90347.0 64960.0 75329.0 57350.0 74366.0 61126.0 72718.0 59455.0 63808.0 51997.0 True False 89058.63521238948 64809.58911113049 69135.74039834895 61567.71031399166 69991.9380891814 58511.78347166553 76482.98222809329 62217.49635114857 56621.2711119721 60984.6121683526 1.4603460126389987 1.0627203618548684 1.1336587696498674 1.0095613979478852 1.147698338983667 0.9594515959229085 1.2541357484894102 1.0202163158698543 0.9284517700246224 1.0 15.89615764273394 -4.761259142541867 24.875219100003093 1.0647626320422743 1.4603464528542651 0.6277585894673312 0.09294523855258904 2.5734486349582055 354151.5109850422 0.02215288045150005 0.12466559722499505 1.7327697494005595e-05 4.761259142541867 0.39558382081199084 T(ph)TPAPVNQTDR ddPTM_PC-9_Lapatinib_30min_R1 1 TTPAPVNQTDR 11 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 T(0.977)T(0.023)PAPVNQTDR 94.76700000000001 0.011382 0.0 10075.0 17549.0 19457.0 17979.0 22183.0 16323.0 19784.0 16148.0 16431.0 12938.0 True False 9931.328652471286 17508.36636870734 17857.32056619198 19301.2356361858 20878.239553456024 15624.903340771474 20808.318716144535 16898.295031172263 14580.367753899414 15174.316061198644 0.6544827860720593 1.1538158489710755 1.1768122196857285 1.2719674190482866 1.3758932837073659 1.0296940750249035 1.3712854426007555 1.113611642397637 0.9608583144766584 1.0 13.889343872152098 -4.760875148176433 5.366831638738743 1.1799380622065638 0.6266985848667228 0.5454925553993211 0.13814444423010155 0.11615789247953226 10.082227443324257 0.033941638803890874 0.2401698879059137 1.7343025067572136e-05 4.760875148176433 -0.553239477339841 T(ph)TPDQELAPASEPVWERPWSVEEIR ddPTM_PC-9_AZD4547_30min_R2 1 TTPDQELAPASEPVWERPWSVEEIR 25 1 E7ESD2;Q641Q2-2;Q641Q2;A0A087WYF6;Q5T1D7 E7ESD2 FAM21A WASH complex subunit FAM21A 1 T(0.756)T(0.243)PDQELAPAS(0.002)EPVWERPWSVEEIR 58.294 0.0032305 4545300.0 1002.0 563.24 795.18 2501.7 981.9 826.83 1033.2 2701.6 1964.5 612.42 True False 1320.6151571052692 745.2963152414842 784.6353936386182 1924.9717158797066 845.5801338277272 775.1281893922517 1125.1527984263853 2284.1297965920135 2068.3394593937624 590.9793622061402 2.2346214462978553 1.2611207140284477 1.327686622946621 3.2572570871066304 1.4308116118829535 1.3115994211687518 1.9038783253380673 3.8649907977586593 3.4998505729076586 1.0 9.206963940206762 -7.642957524429809 8.669712764403348 3.007794269487286 1.7908315432209305 0.182863274980278 0.9061833194023493 0.3379228766930868 24.057746335826014 0.41779513633721693 0.2403246239625667 2.2753199544063128e-08 7.642957524429809 -1.2169627262663554 T(ph)TPDQELAPASEPVWERPWSVEEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTPDQELAPASEPVWERPWSVEEIR 25 1 E7ESD2;Q641Q2-2;Q641Q2;A0A087WYF6;Q5T1D7 E7ESD2 FAM21A WASH complex subunit FAM21A 1 T(0.61)T(0.39)PDQELAPAS(0.001)EPVWERPWSVEEIR;T(0.774)T(0.226)PDQELAPASEPVWERPWSVEEIR 84.03 8.198099999999999e-06 9352100.0 2197.57 4470.3 2049.14 2214.1099999999997 2897.9 1746.1 2088.45 1542.8 2403.1 1138.24 True False 2569.5751970140386 4914.0818408165205 2097.9992690067256 2090.060594941472 2330.0772977492115 1654.531442166625 1890.6168969313753 1502.303134731722 2438.2407912814556 1344.593901697118 1.9110418348400768 3.654695915706646 1.5603218684531257 1.5544177259047818 1.7329227023923262 1.2305064302897033 1.4060876630074541 1.1172913493327217 1.8133659450663575 1.0 10.392954796125924 -5.386068722371555 7.371724667792236 1.429853395119792 2.776352361615743 0.5844942361861192 0.458359734746663 0.15236506119989374 8.396201222335886 0.1104556466908606 0.23136668936837299 4.110846662865214e-06 5.386068722371555 1.3464989664959508 T(ph)TPDQELAPASEPVWERPWSVEEIRR ddPTM_PC-9_AZD4547_30min_R2 3 TTPDQELAPASEPVWERPWSVEEIRR 26 2 E7ESD2;Q641Q2-2;Q641Q2;A0A087WYF6;Q5T1D7 E7ESD2 FAM21A WASH complex subunit FAM21A 1 T(0.5)T(0.5)PDQELAPASEPVWERPWSVEEIRR;T(0.5)T(0.5)PDQELAPASEPVWERPWSVEEIRR;T(0.5)T(0.5)PDQELAPASEPVWERPWSVEEIRR 60.464 0.0011061 17741800.0 38389.3 34072.8 47947.1 57238.4 53706.8 45251.7 45052.7 53007.6 39519.4 48300.9 True False 50596.29885295544 45086.16627008034 47311.290125921405 44042.971204464586 46250.537866848936 42422.10404547651 49062.30302135542 44816.49341347006 41608.314803545865 46609.900192649766 1.0855268654047519 0.9673087924181029 1.0150480891478555 0.9449273871521833 0.9922900001005044 0.9101522180939221 1.0526154919570583 0.9615230504299058 0.8926926389365529 1.0 15.508348803138098 -2.3430816112450183 1.3858995534063183 0.9689579559529761 121.93496199851803 0.3547559479949054 0.045704211941918524 1688.8416907516948 4.036223023882341 0.012489259410128706 648966.4514539102 0.0045385632139224134 2.3430816112450183 120.96600404256506 T(ph)TPDQELAPASEPVWERPWSVEEIRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TTPDQELAPASEPVWERPWSVEEIRR 26 2 E7ESD2;Q641Q2-2;Q641Q2;A0A087WYF6;Q5T1D7 E7ESD2 FAM21A WASH complex subunit FAM21A 1 T(0.762)T(0.238)PDQELAPASEPVWERPWSVEEIRR;T(0.767)T(0.233)PDQELAPASEPVWERPWSVEEIRR;T(0.5)T(0.5)PDQELAPASEPVWERPWSVEEIRR 73.60300000000001 5.1433999999999996e-05 12047900.0 29998.8 25023.2 26443.9 37812.0 39253.0 35654.0 35755.8 34655.0 33072.0 29521.1 True False 35077.00433669223 27507.337923432446 27074.422865049215 35693.516228158 31561.656430018218 33784.241474720184 32368.751774425487 33745.34297000763 33555.61543392298 34873.041741100984 1.0058487182479083 0.7887851632687549 0.7763711312036081 1.023527471252673 0.905044551729481 0.9687781675466081 0.9281883701092822 0.9676627356034658 0.9622222140254173 1.0 15.089824585746525 -5.764652660979938 24.99985487631966 0.9598310116172728 0.8501800231627886 0.3585800899261311 0.06578036314508916 86.5258874095951 673193.9472458562 0.017956013126173235 0.027943776833118602 1.7192828814617033e-06 5.764652660979938 -0.10965098845448418 T(ph)TPDQELAPASEPVWERPWSVEEIRR ddPTM_PC-9_Lapatinib_30min_R1 2 TTPDQELAPASEPVWERPWSVEEIRR 26 2 E7ESD2;Q641Q2-2;Q641Q2;A0A087WYF6;Q5T1D7 E7ESD2 FAM21A WASH complex subunit FAM21A 1 T(0.5)T(0.5)PDQELAPASEPVWERPWSVEEIRR;T(0.5)T(0.5)PDQELAPASEPVWERPWSVEEIRR 54.728 0.0024464 7325000.0 12738.099999999999 13839.0 13493.1 13754.4 15318.4 16587.1 13521.099999999999 14350.4 13959.4 14581.0 True False 12556.452358118548 13806.956645765635 12383.749402872223 14765.944459333348 14417.401829133138 15877.708399418629 14221.156398749601 15017.171972710825 12387.145373001249 17101.306422038757 0.7342393644228739 0.8073626835884518 0.7241405479357451 0.8634395580623135 0.8430585052001159 0.9284500264235219 0.8315830409554292 0.878130103169073 0.7243391275088619 1.0 14.061818920836243 -5.773909947554517 24.94349160532405 0.8620093011879054 0.7604590510361529 0.3503227291985258 0.06939896008302451 245.03800507080132 490122.12842190336 0.018515679323692264 0.027681643395744242 1.6830230054655026e-06 5.773909947554517 -0.10155025015175256 T(ph)TPDQELVPASEPVWERPWSVEEIR ddPTM_PC-9_AZD4547_30min_R2 1 TTPDQELVPASEPVWERPWSVEEIR 25 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;A0A0A0MT65 J3KP36 FAM21C WASH complex subunit FAM21C 1 T(0.5)T(0.5)PDQELVPAS(0.001)EPVWERPWSVEEIR 52.909 0.0091601 2646600.0 831.86 1190.6 1896.4 1575.4 3703.7 1482.1 805.99 772.13 1328.3 920.76 True False 1096.374176237116 1575.438166548027 1871.2524969142528 1212.2158696873694 3189.5051855155843 1389.4240527052186 877.7215485904779 652.8150502822739 1398.5112262218045 888.5244726575322 1.2339268190980894 1.7730948499774806 2.1060224613931346 1.3643021739870511 3.5896649824128466 1.563743144349779 0.9878417259180906 0.7347181426863086 1.5739704074091818 1.0 9.795267702770861 -7.000499795736193 24.999999943929918 1.0839922710231538 2.029892992466487 0.3310699674042348 0.6292514242514043 21.798239515798436 1090418.763705767 0.22567992809399157 0.19680559184874513 9.988498397302314e-08 7.000499795736193 0.9459007214433333 T(ph)TPDQELVPASEPVWERPWSVEEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTPDQELVPASEPVWERPWSVEEIR 25 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;A0A0A0MT65 J3KP36 FAM21C WASH complex subunit FAM21C 1 T(0.498)T(0.498)PDQELVPAS(0.004)EPVWERPWSVEEIR 75.112 0.00012412 1256000.0 629.09 793.72 1025.6 2033.8 1104.0 648.62 874.61 1105.9 1006.3 1047.7 True False 735.5825119061335 872.5152760872621 1050.054193609659 1919.8527796685637 887.6791251303108 614.6052253697477 791.7606091719459 1076.8712967979063 1021.0152337674372 1237.6397164113637 0.5943430080274205 0.7049832552377929 0.8484328514071736 1.5512210493982304 0.7172354873227631 0.496594620566836 0.639734325485061 0.8701007914648874 0.8249696743151984 1.0 10.273375684032857 -5.091435778289498 3.487642800141157 0.860353210517581 0.613471941278733 0.10425180597887773 0.26466455129465033 0.6409950105652983 14.207568006284353 0.07529649597997025 0.26619348548766963 8.101477341913815e-06 5.091435778289498 -0.246881269238848 T(ph)TPDQELVPASEPVWERPWSVEEIRR ddPTM_PC-9_AZD4547_30min_R2 1 TTPDQELVPASEPVWERPWSVEEIRR 26 2 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;A0A0A0MT65 J3KP36 FAM21C WASH complex subunit FAM21C 1 T(0.5)T(0.5)PDQELVPASEPVWERPWSVEEIRR 48.867 0.012898 4488400.0 4753.7 4807.9 6634.3 8155.2 7721.0 6224.3 6302.4 6027.3 4785.1 6952.8 True False 6265.277716897525 6361.959651391117 6546.324847225389 6275.144636583999 6649.072424161198 5835.093537044126 6863.301390633421 5095.919278575303 5038.030617024733 6709.384588267618 0.9338081063132555 0.9482180619838031 0.9756967663878795 0.9352787210256283 0.9910107755319489 0.8696913197147287 1.022940524625008 0.7595211172551198 0.7508931036438868 1.0 12.711964727365963 -7.7650778846533 24.999997633501657 0.8164053284486411 0.951916480524987 0.3301135877406606 0.0746675099901672 89.53646272411868 615181.1623064231 0.03622469072089248 0.018471677129329338 1.717600331891031e-08 7.7650778846533 0.1355111520763459 T(ph)TPESPPYSSGSYDSIKTEVSGCPEDLTVGR ddPTM_PC-9_AZD4547_30min_R2 1 TTPESPPYSSGSYDSIKTEVSGCPEDLTVGR 31 1 A0A087WTU5;A0A087X0N3;Q96MY1-2;Q96MY1 A0A087WTU5 NOL4L Nucleolar protein 4-like 1 T(0.17)T(0.17)PES(0.112)PPY(0.1)S(0.112)S(0.112)GS(0.112)Y(0.1)DS(0.011)IKT(0.001)EVSGCPEDLTVGR 60.172 0.00062332 10724000.0 21508.0 12560.0 27947.0 71318.0 45141.0 28350.0 19480.0 23208.0 16251.0 30198.0 True False 28347.096605808514 16619.77437581323 27576.404519754593 54876.73695211621 38873.9513403783 26577.270018347583 21213.68226223964 19621.7368667854 17109.994682925964 29140.77721155585 0.9727639177230798 0.5703270799936873 0.9463167135027235 1.8831596890406443 1.3340053032272157 0.912030239461434 0.7279724253142877 0.673342949103099 0.5871495656657006 1.0 14.830751735479824 -7.002373597429975 4.547542802401417 0.728267733216013 1.1405280389856194 0.2422868063369934 0.3283890565485458 0.3222262515853604 17.20995513823905 0.13993949311956463 0.11544083473479207 9.945494981223865e-08 7.002373597429975 0.41226030576960637 T(ph)TPESPPYSSGSYDSIKTEVSGCPEDLTVGR ddPTM_PC-9_Lapatinib_30min_R1 1 TTPESPPYSSGSYDSIKTEVSGCPEDLTVGR 31 1 A0A087WTU5;A0A087X0N3;Q96MY1-2;Q96MY1 A0A087WTU5 NOL4L Nucleolar protein 4-like 1 T(0.308)T(0.308)PES(0.257)PPY(0.064)S(0.018)S(0.018)GS(0.011)Y(0.009)DS(0.003)IKT(0.003)EVSGCPEDLTVGR 62.683 0.00028603 7333200.0 22589.0 9935.8 14331.0 11296.0 10481.0 12541.0 6930.1 5383.9 11605.0 8335.5 True False 22266.87671768474 9912.794265553734 13152.760499259766 12126.745522351353 9864.528186438827 12004.650664498859 7288.906668760272 5634.055648893262 10297.922693932369 9776.280068644402 2.2776430872824114 1.0139638181343817 1.3453747649317858 1.2404253394136724 1.009026758355406 1.2279364523323693 0.7455705664711961 0.5762985112265192 1.0533579870487793 1.0 13.255069900409637 -2.5361948921073605 1.1095236041211476 0.9800421253077711 199.99999990524432 0.7214472429112464 0.22926029054800098 145.03337790238322 1.480948428211192 0.07465408827518706 72015.7972858109 0.0029094112103205277 2.5361948921073605 199.01995777993656 up T(ph)TPLKPSPLPVIPDTIK ddPTM_PC-9_AZD4547_30min_R2 1 TTPLKPSPLPVIPDTIK 17 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 T(0.5)T(0.5)PLKPSPLPVIPDTIK 87.352 0.0020976 4835700.0 27605.0 32685.0 32488.0 43339.0 30756.0 36709.0 35961.0 34468.0 29633.0 33728.0 True False 36382.81578033032 43249.78705998848 32057.187892717888 33347.863130875274 26486.06028720398 34413.580426931985 39161.459334312094 29141.76259584449 31199.339883031498 32547.1929860042 1.1178480367254864 1.3288330910314312 0.9849447817666789 1.0246002825870537 0.813774026491114 1.0573440370642826 1.2032207923783822 0.8953694596144098 0.9585877312506704 1.0 14.99024550389898 -5.277441624011378 24.47651858557474 0.9931368394402984 1.2233405566401419 0.42727369431432316 0.10702451625181504 510.4161337398893 780716.1395984556 0.028669954238487866 0.06000488922460681 5.279081611478664e-06 5.277441624011378 0.23020371719984345 T(ph)TPLKPSPLPVIPDTIK ddPTM_PC-9_Lapatinib_30min_R1 2 TTPLKPSPLPVIPDTIK 17 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 T(0.852)T(0.148)PLKPSPLPVIPDTIK;T(0.77)T(0.23)PLKPSPLPVIPDTIK 81.665 0.0035702 9183800.0 76901.0 98253.0 90000.0 90309.0 97479.0 91413.0 86668.0 84849.0 93835.0 70022.0 True False 75804.37763808364 98025.50121514613 82600.54741004683 96950.6251219924 91745.47687108768 87503.47908411096 91155.24497021918 88791.39429650344 83266.31417364432 82125.2094015499 0.9230342082592367 1.193610365555989 1.0057879670805192 1.180522105556576 1.1171414665440869 1.0654886571584141 1.1099544906426608 1.0811709941871726 1.013894695434078 1.0 16.325537523549926 -8.27548340328724 3.5265916631979675 1.0013162706446694 1.0907444607432784 0.14590732725899536 0.07463482603806995 0.40001602538771747 10.113633201825623 0.06198387167485138 0.017741625718607178 5.3029385760386405e-09 8.27548340328724 0.08942819009860892 T(ph)TPNSGDVQVTEDAVR ddPTM_PC-9_AZD4547_30min_R2 2 TTPNSGDVQVTEDAVR 16 0 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 T(0.997)T(0.003)PNSGDVQVTEDAVR;T(0.989)T(0.011)PNSGDVQVTEDAVR 207.21 1.1519e-16 12663000.0 37125.4 48289.8 39374.4 36054.8 35594.5 47328.0 46453.0 48879.0 42983.2 37132.2 True False 48930.50494370855 63898.53349149251 38852.26972922406 27742.922901107107 30652.81808079339 44368.57267824885 50587.22700861484 41325.87367768026 45255.204200058004 35832.21298016207 1.3655451582294997 1.7832706432859424 1.0842832886356755 0.7742453115152708 0.8554542276739601 1.2382314400400778 1.4117807079518547 1.1533162548615032 1.2629754189369444 1.0 15.12896952599832 -5.2768461525451436 24.44224300296701 1.099067393469461 1.5744078831679296 0.4707156873190379 0.20226271144125033 491.28567407007034 779405.7425079695 0.05822861976969596 0.12197216494210958 5.2863248500570145e-06 5.2768461525451436 0.47534048969846854 T(ph)TPNSGDVQVTEDAVR ddPTM_PC-9_Lapatinib_30min_R1 1 TTPNSGDVQVTEDAVR 16 0 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 T(0.996)T(0.004)PNSGDVQVTEDAVR 195.89 3.1813e-50 0.0 7837.2 12665.0 10939.0 10507.0 12353.0 11641.0 11442.0 10898.0 11021.0 9914.9 True False 7725.440090833545 12635.674970635277 10039.637645761113 11279.719830324511 11626.420826932426 11143.141566496392 12034.41077386403 11404.360865104994 9779.698923724995 11628.677254226199 0.664343839109121 1.0865960671531327 0.8633516457869203 0.9699916494135336 0.9998059601066878 0.9582466967553555 1.0348907713893578 0.980710068375173 0.8409983964574104 1.0 13.505399381150056 -4.747311581176049 24.999824837209335 0.9690865740329507 0.664343068019309 0.6379020841707874 0.06919386711289767 461.4835457652469 816571.174037979 0.01642497500419366 0.3409734755682828 1.7893216586066223e-05 4.747311581176049 -0.30474350601364175 T(ph)TPNSGDVQVTEDAVRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTPNSGDVQVTEDAVRR 17 1 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 T(0.646)T(0.283)PNS(0.07)GDVQVTEDAVRR;T(0.672)T(0.131)PNS(0.198)GDVQVTEDAVRR 136.61 4.3944e-05 25959000.0 38121.0 28194.0 37909.0 44960.0 53099.0 45279.0 36700.0 40265.0 35305.0 31946.0 True False 44574.13237592989 30992.91399234528 38812.89433068311 42441.03696228668 42694.632124360876 42904.489530876046 33223.51031500942 39208.08641429396 35821.268834502014 37737.556915603134 1.1811610506640953 0.8212750513144854 1.0284951518585286 1.1246365804019185 1.1313565480628178 1.1369175176556428 0.8803831787338805 1.0389672681244189 0.9492206640353869 1.0 15.203713407155762 -7.2554592217867215 24.96020092986384 0.9703900509048865 1.0626040432789756 0.1991000963736319 0.10083911490273219 956.4481015600135 3992066.5297715035 0.04078841691700983 0.030750408317108353 5.5531675630848086e-08 7.2554592217867215 0.09221399237408912 T(ph)TPNSGDVQVTEDAVRR ddPTM_PC-9_Lapatinib_30min_R1 2 TTPNSGDVQVTEDAVRR 17 1 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 T(0.828)T(0.169)PNS(0.004)GDVQVTEDAVRR;T(0.499)T(0.499)PNS(0.002)GDVQVTEDAVRR 71.376 0.011420999999999999 28547000.0 49336.0 42594.0 50086.0 35811.0 36888.0 37486.0 33715.0 36649.0 48918.0 27761.0 True False 48632.45959288568 42495.37620996754 45968.12241755107 38444.660401994 34718.32036459836 35882.81116413399 35460.59773123804 38351.84633375233 43408.33971062327 32559.451860792684 1.4936510541029018 1.305162519063764 1.4118211391913753 1.1807526909962553 1.0663054314622948 1.1020704930030847 1.0891030316741557 1.177902088085663 1.3332024106614202 1.0 14.990788791550028 -5.825161605089327 4.495068987088723 1.1331968287890077 1.3948808437870848 0.6392475609043109 0.09265305920689809 0.1363361729321428 5.418784207421038 0.026616123853474265 0.04158560099095597 1.495678996213624e-06 5.825161605089327 0.26168401499807703 T(ph)TPPESAPQNGPSPMAALMSVADTLGTAHS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 TTPPESAPQNGPSPMAALMSVADTLGTAHSPK 32 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 2 T(0.548)T(0.265)PPES(0.181)APQNGPS(0.021)PMAALMS(0.003)VADT(0.016)LGT(0.042)AHS(0.925)PK 55.504 0.0040365999999999996 0.0 1807.6 3196.5 2965.1 1090.2 3555.4 3079.1 2879.4 2784.0 4054.4 2215.6 True False 2382.3791995843153 4229.706114035587 2925.7808366380773 838.8712334220963 3061.79408067125 2886.5633902467025 3135.6610218630804 2353.796769955643 4268.707306778352 2138.032518376155 1.114285764649521 1.9783170170152824 1.3684454335896725 0.39235662985108505 1.4320615118598363 1.3501026600096147 1.4666105379185852 1.1009171982769288 1.9965586444964147 1.0 11.062068080537724 T(ph)TPPPGRPPAPS(ph)SEEEDGEAVAH ddPTM_PC-9_Lapatinib_30min_R1 1 TTPPPGRPPAPSSEEEDGEAVAH 23 1 Q96KN1 Q96KN1 FAM84B Protein FAM84B 2 T(0.5)T(0.5)PPPGRPPAPS(0.5)S(0.5)EEEDGEAVAH 65.02199999999999 0.0067277000000000005 3739000.0 39187.0 33973.0 30059.0 31051.0 27045.0 34189.0 25977.0 32006.0 35196.0 24794.0 True False 38628.18619398433 33894.3376057949 27587.665051095482 33334.594123099465 25454.26627251579 32726.816168451634 27321.961953562823 33493.1156036475 31231.85584968922 29079.609864071663 1.3283598498929687 1.1655705755417274 0.9486944694254821 1.1463219169348247 0.8753303910024238 1.12542143176708 0.9395573765011049 1.151773210170498 1.0740122029036123 1.0 14.827720293547511 -4.932227534310843 3.2226915187870095 1.0365758197228898 1.3314378819182573 0.5163687340655347 0.08952146836349484 0.20523634724494233 3.894477380292499 0.021488923194283836 0.1262622871446087 1.1688868307555156e-05 4.932227534310843 0.2948620621953675 T(ph)TPPPGRPPAPSSEEEDGEAVAH ddPTM_PC-9_AZD4547_30min_R2 2 TTPPPGRPPAPSSEEEDGEAVAH 23 1 Q96KN1 Q96KN1 FAM84B Protein FAM84B 1 T(0.493)T(0.493)PPPGRPPAPS(0.007)S(0.007)EEEDGEAVAH;T(0.5)T(0.5)PPPGRPPAPSSEEEDGEAVAH 67.194 0.0010852 93976000.0 301370.0 273740.0 334530.0 494580.0 447070.0 409940.0 335960.0 389870.0 308450.0 382850.0 True False 397199.39111458685 362221.1017225409 330093.91362198134 380562.2221848284 385002.04748992925 384306.38699546334 365859.7891592424 329624.5498213392 324754.03728684474 369446.53803046985 1.075120078894414 0.9804425388678754 0.8934822217626439 1.0300873956313588 1.042104899784381 1.0402219196428577 0.9902915618309797 0.8922117705543464 0.8790285030633063 1.0 18.49500608400804 -7.672464926472666 5.575212578514032 0.9146579546297127 1.0064789468176467 0.3257051844959977 0.05501176119616964 0.23593169873813744 11.502352900974584 0.027877379786143536 0.01564972316174599 2.125862022436494e-08 7.672464926472666 0.09182099218793405 T(ph)TPPPGRPPAPSSEEEDGEAVAH ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTPPPGRPPAPSSEEEDGEAVAH 23 1 Q96KN1 Q96KN1 FAM84B Protein FAM84B 1 T(0.496)T(0.496)PPPGRPPAPS(0.001)S(0.006)EEEDGEAVAH;T(0.5)T(0.5)PPPGRPPAPSSEEEDGEAVAH 87.419 2.0298e-05 112868000.0 290490.0 336990.0 303720.0 379070.0 416150.0 367410.0 410760.0 369960.0 295330.0 309320.0 True False 339664.2195609733 370444.1401106772 310961.8366645138 357831.9368615219 334608.39485777024 348142.37281166035 371849.83915512933 360248.9420050219 299648.64254053147 365397.26742422715 0.9295751496866622 1.013812015404567 0.8510239796169201 0.9792956016993913 0.9157386348740508 0.9527777130513299 1.0176590585265946 0.9859103340988371 0.820062625680883 1.0 18.479106319435992 -6.9861202886299045 24.305113074054194 0.9590888002544743 0.9390492029817811 0.017291991926627448 0.06383001195895567 925.579141806473 1620793.6694009707 0.022177210265322173 0.01954925924740714 1.0324753964818259e-07 6.9861202886299045 -0.02003959727269322 T(ph)TPPPGRPPAPSSEEEDGEAVAH ddPTM_PC-9_Lapatinib_30min_R1 2 TTPPPGRPPAPSSEEEDGEAVAH 23 1 Q96KN1 Q96KN1 FAM84B Protein FAM84B 1 T(0.496)T(0.496)PPPGRPPAPS(0.004)S(0.004)EEEDGEAVAH;T(0.497)T(0.497)PPPGRPPAPS(0.003)S(0.003)EEEDGEAVAH 77.795 0.0002097 121579000.0 335010.0 252610.0 238700.0 221218.0 255000.0 259900.0 214946.0 205994.0 295380.0 230690.0 True False 330232.6959666904 252025.09706531267 219075.0074086464 237487.10968161473 240001.40134928905 248784.68285649142 226074.85214114477 215565.2332580696 262111.19391070615 270564.4591248972 1.2205324270407936 0.9314789454625804 0.8096961741287595 0.8777468794302603 0.8870396434385356 0.9195024492911988 0.835567438799435 0.7967241298257913 0.9687569267540461 1.0 18.04561281629455 -4.773527464157303 3.7917785463945948 0.8780751808898712 1.2582360812882687 0.7205215311460785 0.06173578271275939 0.12407935342753484 3.1650764027936567 0.014753663366452207 0.13400473420138484 1.6845058976797826e-05 4.773527464157303 0.38016090039839745 T(ph)TPTLGLEEVLSSR ddPTM_PC-9_AZD4547_30min_R2 1 TTPTLGLEEVLSSR 14 0 O43474-4;O43474-1;O43474 O43474-4 KLF4 Krueppel-like factor 4 1 T(0.589)T(0.411)PTLGLEEVLSSR 100.73 0.0046107 3709100.0 6523.7 6071.9 7998.2 10980.0 9761.8 9819.1 8338.1 10241.0 7046.4 7607.1 True False 8598.10089861043 8034.522932523912 7892.138642068959 8448.730639308944 8406.542570933405 9205.11012476744 9080.17474695997 8658.488764768581 7418.858318489285 7340.777744421036 1.1712792837441448 1.0945056794057169 1.075109329943541 1.1509312682474209 1.1451841839677472 1.2539693265830436 1.2369499613117791 1.1795056418032817 1.010636553344445 1.0 12.841717207209806 -8.266826880748768 22.8947338333294 1.0053181525433224 1.1626317965004034 0.5967576344783356 0.051985075942490265 117.27783879110683 498357.41589727753 0.05224830668563706 0.01514848569392962 5.40969922379506e-09 8.266826880748768 0.15731364395708103 T(ph)TPTLGLEEVLSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTPTLGLEEVLSSR 14 0 O43474-4;O43474-1;O43474 O43474-4 KLF4 Krueppel-like factor 4 1 T(0.996)T(0.004)PTLGLEEVLSSR 131.08 4.2705e-05 2751800.0 9864.8 12339.0 13806.0 13983.0 15947.0 15223.0 14938.0 13317.0 13999.0 11192.0 True False 11534.715801318778 13563.934374389879 14135.187399546565 13199.57784349766 12822.299826497352 14424.679081440087 13522.96449824553 12967.44286052783 14203.708891493947 13221.021004176753 0.8724527249200162 1.025936980971802 1.0691449166506135 0.9983781010050344 0.9698418769962291 1.0910412347793015 1.0228381373854099 0.980820078602945 1.074327685207273 1.0 13.690545974003552 -4.761431491882826 21.306650203387274 1.0259079002616511 0.8724520082251502 0.5841171517861221 0.03882152825561405 0.03687714513497916 54499.71759902835 0.009490329263859976 0.052857103352911744 1.7320822378461096e-05 4.761431491882826 -0.1534558920365009 T(ph)TPTLGLEEVLSSR ddPTM_PC-9_Lapatinib_30min_R1 2 TTPTLGLEEVLSSR 14 0 O43474-4;O43474-1;O43474 O43474-4 KLF4 Krueppel-like factor 4 1 T(0.574)T(0.424)PT(0.003)LGLEEVLSSR;T(0.986)T(0.014)PTLGLEEVLSSR 108.66 0.0016237000000000003 5543600.0 14924.5 13882.7 13601.1 14776.7 13896.3 14514.7 14737.4 16127.5 17323.6 14255.7 True False 14711.673893181905 13850.555461100554 12482.870059764287 15863.427811626161 13078.946955176967 13893.940116418285 15500.430461347996 16876.842526333337 15372.433742404717 16719.778750473775 0.8798964455654075 0.8283934654762152 0.7465930169327492 0.9487821608390992 0.7822440207114798 0.830988275848123 0.9270715057104911 1.0093938908046323 0.9194160982524437 1.0 14.029268136196343 -7.397860019481581 3.498799771148083 0.9729612202413364 0.8343728693540382 0.5695569697942744 0.055489334764155566 0.18114917606216355 4.052987653729023 0.024804156426875494 0.015736838155334484 4.000736795520304e-08 7.397860019481581 -0.13858835088729815 T(ph)TPTMSEEPPLDLTGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTPTMSEEPPLDLTGK 16 0 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 T(0.846)T(0.153)PT(0.001)MSEEPPLDLTGK 145.7 0.00011335 5709800.0 21655.0 19798.0 21336.0 23381.0 19128.0 18761.0 19980.0 21199.0 18365.0 15125.0 True False 25320.763794254133 21763.414599576216 21844.73115723058 22071.038372224742 15380.005711496917 17777.140133147044 18087.34975732667 20642.548712197153 18633.553381833437 17867.04277056588 1.4171770963669206 1.2180759221906161 1.2226271262537936 1.2352933082235922 0.8608030947815213 0.9949682418868476 1.0123303553693688 1.1553422117622976 1.0429008102297883 1.0 14.12501324877548 -6.116320940470011 6.69002756614409 1.018514871936777 1.27108694089369 0.697911799263533 0.08472013155955667 0.15577527820639023 8.033126635418538 0.026487096495003398 0.03440006177036214 7.650310455740595e-07 6.116320940470011 0.2525720689569131 T(ph)TPTQPSEQK ddPTM_PC-9_AZD4547_30min_R2 3 TTPTQPSEQK 10 0 O95104-2;O95104-3;O95104 O95104-2 SCAF4 Splicing factor, arginine/serine-rich 15 1 T(0.991)T(0.009)PTQPSEQK;T(0.603)T(0.397)PTQPSEQK;T(0.998)T(0.002)PTQPSEQK 152.54 0.00041668 46581200.0 172429.0 148125.0 165588.0 184819.0 176235.0 189434.0 162013.0 183203.0 161590.0 165200.0 True False 227257.8352539962 196003.50950774958 163392.19492672294 142211.8349750857 151767.81228753366 177588.6620337093 176431.8431392315 154893.18593612933 170131.31750747687 159416.39828296693 1.425561220186455 1.2295065728422736 1.0249396968353213 0.8920778320600191 0.9520213348324625 1.1139924370796928 1.1067358505118265 0.9716264299309484 1.0672134067756993 1.0 17.28244051345594 -5.0022253182587235 2.3852176376850163 1.0144835804793775 1.4395143047471288 0.8017845562633854 0.0655299336906213 0.1698462838459802 1.6272339190807452 0.019542695054146863 0.12346578623274894 9.948891205664444e-06 5.0022253182587235 0.42503072426775135 T(ph)TPTQPSEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TTPTQPSEQK 10 0 O95104-2;O95104-3;O95104 O95104-2 SCAF4 Splicing factor, arginine/serine-rich 15 1 T(0.994)T(0.006)PTQPSEQK;T(0.988)T(0.012)PTQPSEQK;T(0.997)T(0.003)PTQPSEQK 121.61 0.0014870999999999999 56560600.0 205376.0 203150.0 189365.0 225278.0 222197.0 174923.0 223538.0 180853.0 172155.0 163164.0 True False 240142.10043910154 223317.38942842226 193880.17977076207 212656.40402113026 178659.09290451038 165749.72994565775 202362.86236502993 176105.80037959252 174672.44118973767 192744.3415944868 1.2459099886020752 1.1586196906275872 1.0058929780603623 1.103308155569808 0.9269226345455565 0.859946022666529 1.0499029994394309 0.9136755918370877 0.9062390093776634 1.0 17.556328981926548 -4.801668422324625 0.6966491843037974 0.9401746698427956 1.4400714859701615 0.7082870477878147 0.06324617357319283 1.6365352192266933 0.61243568067559 0.02785541104613181 0.6470314979955752 1.578816213441579e-05 4.801668422324625 0.4998968161273659 T(ph)TPTQPSEQK ddPTM_PC-9_Lapatinib_30min_R1 4 TTPTQPSEQK 10 0 O95104-2;O95104-3;O95104 O95104-2 SCAF4 Splicing factor, arginine/serine-rich 15 1 T(0.906)T(0.093)PTQPSEQK;T(0.989)T(0.011)PTQPSEQK;T(0.97)T(0.029)PT(0.001)QPSEQK;T(0.88)T(0.12)PTQPSEQK 130.01 0.00055607 85043900.0 205194.0 230812.0 226281.0 220054.0 239497.0 231872.0 211595.0 211230.0 228474.0 180942.0 True False 202267.89593202923 230277.5689950472 207677.04964991933 236237.50523862432 225410.25732921867 221955.37508003204 222550.3537577133 221044.51693302713 202740.8521821202 212217.58360993981 0.9531156301534452 1.0851012676607514 0.9786043461489691 1.113185350714546 1.0621657899164814 1.0458858842158456 1.0486895099454403 1.04159378866226 0.955344268525656 1.0 17.695184672328928 -8.246157893618383 22.24003797523903 0.977672157945525 1.0439552450629532 0.23787328317728373 0.04513179321019708 213.7084457131367 311027.1059151234 0.029093240653497183 0.01086229354327274 5.6733830441398475e-09 8.246157893618383 0.06628308711742825 T(ph)TPVDLCLLEESVGSLEGSR ddPTM_PC-9_Lapatinib_30min_R1 1 TTPVDLCLLEESVGSLEGSR 20 0 Q9UKK3 Q9UKK3 PARP4 Poly [ADP-ribose] polymerase 4 1 T(0.5)T(0.5)PVDLCLLEESVGSLEGSR 80.975 0.0032654000000000003 486480.0 0.0 0.0 0.0 0.0 0.0 512.45 864.8 553.79 765.05 525.73 True False 0.0 0.0 0.0 0.0 0.0 490.5337080792956 909.575112501102 579.5211051097904 678.8820126663467 616.6017300088084 0.0 0.0 0.0 0.0 0.0 0.7955438400607279 1.4751420053396678 0.939862924324769 1.101005689128781 1.0 9.268195127016808 -6.860841342636229 3.6234767147965536 1.1265267431403108 5.164648793110591e-25 0.9403056187437862 0.13566555557314572 0.0496573371548923 1.258803665515253 0.048296659150926416 0.04267280170659557 1.3777126858352326e-07 6.860841342636229 -1.1265267431403108 down T(ph)TRTPDTSTYCYETAEK ddPTM_PC-9_AZD4547_30min_R2 3 TTRTPDTSTYCYETAEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.333)T(0.333)RT(0.333)PDTSTYCYETAEK;T(0.48)T(0.48)RT(0.04)PDTSTYCYETAEK;T(0.333)T(0.333)RT(0.333)PDT(0.001)STYCYETAEK 92.792 0.0014315999999999999 162836000.0 142064.0 126159.0 174133.0 306878.0 245844.0 191536.0 160639.0 196433.0 150563.0 219898.0 True False 187237.396885233 166937.4295762914 171823.88264351911 236132.01831783727 211712.80417633496 179559.2236414188 174935.55980102226 166078.79343128452 158521.45279954353 212199.43795174162 0.8823651876392552 0.7867006208294308 0.8097282646082941 1.112783429575051 0.9977067150596444 0.8461814290113914 0.8243921920321301 0.782654256930945 0.7470399277664179 1.0 17.69506130945806 -6.97988605372082 23.388893663377115 0.8225347581413476 0.9160477152691391 0.110939961613156 0.10645629551633162 241.86688598533075 281245.046523863 0.04030476117390188 0.03553951934181753 1.047403320263757e-07 6.97988605372082 0.09351295712779151 T(ph)TRTPDTSTYCYETAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TTRTPDTSTYCYETAEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.436)T(0.436)RT(0.127)PDTSTYCYETAEK;T(0.378)T(0.378)RT(0.242)PDT(0.002)STYCYETAEK;T(0.331)T(0.331)RT(0.331)PDT(0.003)S(0.003)T(0.001)YCYETAEK;T(0.333)T(0.333)RT(0.333)PDT(0.001)STYCYETAEK;T(0.333)T(0.333)RT(0.333)PDTSTYCYETAEK 100.59 0.00082522 200234100.0 286357.0 186655.9 266233.0 423647.0 418338.0 416427.0 387469.0 472281.0 366209.0 271985.0 True False 334831.5842914438 205185.86418613177 272581.00441427453 399911.43207210646 336367.67196446104 394588.8350421634 350765.13128736796 459884.1241730837 371564.1138256372 321293.72746792523 1.0421354532197336 0.6386239339409933 0.8483857016520383 1.24469106578506 1.0469163983229042 1.2281249252883568 1.09172729281615 1.4313510811349217 1.1564623958079931 1.0 18.2935332901691 -5.737027891996636 9.269044243733584 1.1831725596037286 0.8217162485536921 0.5144589435243321 0.14539251174411053 0.19544890192731887 67.81373097423884 0.03809442713458784 0.06482801623301189 1.8321967481461586e-06 5.737027891996636 -0.3614563110500365 T(ph)TRTPDTSTYCYETAEK ddPTM_PC-9_Lapatinib_30min_R1 3 TTRTPDTSTYCYETAEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.578)T(0.201)RT(0.201)PDT(0.017)S(0.001)TYCYETAEK;T(0.454)T(0.454)RT(0.091)PDT(0.001)STYCYETAEK;T(0.333)T(0.333)RT(0.333)PDTSTYCYETAEK 81.665 0.0035702 123989800.0 138828.0 106647.0 146307.0 118620.0 111186.0 114121.0 91551.0 78573.0 124903.0 100012.0 True False 136848.2872620627 106400.06542387199 134278.2032213523 127343.71050471974 104646.25808008666 109240.31085904443 96291.06281751663 82223.78842483884 110835.10885310077 117298.940942387 1.166662598678343 0.9070846213021809 1.144752050978064 1.0856339322557598 0.8921330170532837 0.931298355990267 0.8209030878191077 0.7009763921502429 0.9448943695709834 1.0 16.83983046219314 -6.339213558164941 3.7427294188621087 0.8618164026058618 1.0694684591594414 0.4684736660701826 0.10026146310892987 0.2085923261506281 5.617183248821466 0.03191707430726041 0.0371493891945633 4.579166573070122e-07 6.339213558164941 0.20765205655357966 T(ph)TRTPEEGGYSYDISEK ddPTM_PC-9_AZD4547_30min_R2 1 TTRTPEEGGYSYDISEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.461)T(0.461)RT(0.077)PEEGGYSYDISEK 74.726 0.0067962000000000005 379900000.0 100500.0 83422.0 132950.0 179860.0 163700.0 152200.0 121040.0 142730.0 124250.0 125870.0 True False 132456.9094701396 110386.53009387654 131186.9961320131 138396.05580929946 140973.08066768438 142682.90993977073 131812.3255144499 120674.35810911239 130817.6013385975 121463.32961184614 1.0905094557626984 0.9088054019812635 1.0800543386324115 1.139406076315908 1.160622560884709 1.1746994784000642 1.085202636348563 0.9935044469367419 1.0770131343891551 1.0 16.89016129713739 -4.4249833035691335 22.920622680338838 1.0732567365346015 4.11553118364279 0.003997133224195815 0.07827732322975543 12316.24386923946 2626282.757854574 0.020577126325448773 175495.88978765032 3.758518536174699e-05 4.4249833035691335 3.042274447108188 T(ph)TRTPEEGGYSYDISEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 TTRTPEEGGYSYDISEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.333)T(0.333)RT(0.333)PEEGGYSYDISEK;T(0.368)T(0.368)RT(0.265)PEEGGYSYDISEK;T(0.391)T(0.391)RT(0.218)PEEGGYSYDISEK;T(0.358)T(0.358)RT(0.285)PEEGGYSYDISEK;T(0.443)T(0.443)RT(0.114)PEEGGYSYDISEK;T(0.446)T(0.446)RT(0.108)PEEGGYSYDISEK 119.27 7.3013e-05 620926700.0 381966.0 286001.0 359802.0 514571.0 532881.0 481917.0 489807.0 489985.0 438475.0 381361.0 True False 446625.29962761764 314393.2891652387 368381.0442366845 485741.2551316913 428466.79336826573 456644.4241536076 443408.9350644085 477123.41293202096 444886.86736179795 450498.7304479857 0.9914019051363003 0.6978783022376094 0.8177182738569727 1.078230019979545 0.9510943414694845 1.0136419778575412 0.9842623410358405 1.0591004606329504 0.9875429991098816 1.0 18.78116351481752 -5.748990940581807 24.991837740888716 1.0095714783545895 0.8218872918147868 0.5321961883280055 0.07480074266163533 155.6871026576849 312559.0432181245 0.019231582471073688 0.03301336660440624 1.7824159484018514e-06 5.748990940581807 -0.18768418653980268 T(ph)TRTPEEGGYSYDISEK ddPTM_PC-9_Lapatinib_30min_R1 4 TTRTPEEGGYSYDISEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.411)T(0.411)RT(0.177)PEEGGYSYDISEK;T(0.427)T(0.427)RT(0.147)PEEGGYSYDISEK;T(0.348)T(0.348)RT(0.304)PEEGGYSYDISEK;T(0.333)T(0.333)RT(0.333)PEEGGYSYDISEK 115.99 0.00010508 106667900.0 243575.0 189131.0 202093.0 180569.0 187533.0 162111.0 149141.0 151354.0 187488.0 136380.0 True False 240101.57583381524 188693.07878967415 185477.69364153917 193848.6466205257 176502.67764406378 155177.89042919807 156862.7912274824 158386.45938494214 166371.12710383386 159953.101285073 1.501074839467472 1.17967752593543 1.1595754765078015 1.2119092725501024 1.1034651796434733 0.9701461814900081 0.9806798990906531 0.9902056172243966 1.040124422516338 1.0 17.28728943916436 -1.5228787452875767 0.40610395964478885 0.9892720055065174 8.890667082031147 0.8528151870895874 0.05920610470958485 28.81521624949817 0.37843589890386287 0.045092619862529666 183.03715369632533 0.029999999999499937 1.5228787452875767 7.901395076524629 T(ph)TSFFLNSPEKEHQEMDEGSQSLEK ddPTM_PC-9_Lapatinib_30min_R1 1 TTSFFLNSPEKEHQEMDEGSQSLEK 25 1 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 T(0.269)T(0.269)S(0.255)FFLNS(0.206)PEKEHQEMDEGS(0.001)QSLEK 42.828 0.042704 3656400.0 14007.0 19621.0 13930.0 13457.0 13968.0 12985.0 12511.0 14265.0 11676.0 11572.0 True False 13807.257611430787 19575.56878001065 12784.729171355 14446.672671236016 13146.429702144604 12429.661819513418 13158.758363206845 14927.803976942798 10360.925926269223 13572.204781279244 1.0173186916893386 1.442327838068883 0.9419787998623154 1.0644307910209965 0.9686288936841028 0.9158174386418199 0.9695372693873081 1.099880543913793 0.7633929853873497 1.0 13.728367482667593 -5.292197755997361 24.98838958747147 0.9710462294295922 1.2298233396317737 0.4056154464858135 0.12786587559576043 531.619105920372 431891.3968784741 0.03090525106151969 0.06434459643559755 5.1027259443470704e-06 5.292197755997361 0.2587771102021815 T(ph)TSGDDACNLTSFR ddPTM_PC-9_Lapatinib_30min_R1 2 TTSGDDACNLTSFR 14 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GUE9;Q96N67-7;A0A0U1RQT6 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 T(0.853)T(0.135)S(0.012)GDDACNLTSFR;T(0.333)T(0.333)S(0.333)GDDACNLTSFR 235.93 1.7210000000000002e-26 40337000.0 35456.0 114668.0 86378.0 62137.0 94247.0 95631.0 141699.0 144397.0 94154.0 94808.0 True False 34950.39093816594 114402.49329118094 79276.33426872246 66706.76226295557 88703.57675673116 91541.08505674922 149035.48088146801 151106.21176716473 83549.38503442558 111195.43647628097 0.31431497591739016 1.028841622610871 0.7129459335827406 0.5999055750564435 0.7977267733973279 0.8232449816074582 1.3403021347306703 1.3589245796017635 0.7513742261558319 1.0 16.76273805469124 -7.079622269240949 4.777611026067932 1.1412732392091924 0.7135073945575074 0.42036333194900666 0.23219836421604853 0.21510633564997902 8.77665230953569 0.08821497729119436 0.06862022905248134 8.324875183402923e-08 7.079622269240949 -0.427765844651685 T(ph)TSGDDACNLTSFRPATLTVTNFFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTSGDDACNLTSFRPATLTVTNFFK 25 1 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GUE9;Q96N67-7;A0A0U1RQT6 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 T(0.743)T(0.134)S(0.123)GDDACNLTSFRPATLTVTNFFK;T(0.377)T(0.13)S(0.377)GDDACNLT(0.103)S(0.012)FRPATLT(0.001)VTNFFK 64.733 0.00065508 18921700.0 21810.5 16613.5 13203.4 17911.4 22054.5 17937.5 19906.5 17293.9 17431.3 13652.1 True False 25502.58687298912 18262.778485203526 13518.219130173338 16907.882327542302 17733.07904455294 16996.825922835946 18020.81220942059 16839.953449401688 17686.199785720302 16127.117660035865 1.5813481001745482 1.1324266908810356 0.8382290881198466 1.0484131562728798 1.0995814266610555 1.053928313858296 1.117423000768292 1.0442010658316383 1.0966745675544958 1.0 13.977200993545026 -4.782458647528562 4.048605858800208 1.0417146018719206 1.6273053991835558 0.8240768935771262 0.07496793990171682 0.08867943837725684 2.7714319680543458 0.01939061301768176 0.15101416977938342 1.65021812362299e-05 4.782458647528562 0.5855907973116352 T(ph)TSPLEEEEREIK ddPTM_PC-9_AZD4547_30min_R2 1 TTSPLEEEEREIK 13 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 T(0.364)T(0.364)S(0.271)PLEEEEREIK 83.85600000000001 0.006432300000000001 17605000.0 23830.0 16864.0 19776.0 34735.0 33329.0 23900.0 21021.0 22440.0 20983.0 25662.0 True False 31407.444305208173 22314.958206505904 19513.757318591146 26727.382400400376 28701.843650416882 22405.529221816836 22891.828276927074 18972.41361990108 22092.118542356493 24763.581190904893 1.2682916926709866 0.9011199969211919 0.7880022347397035 1.0793019876388776 1.1590344477703582 0.9047774249245454 0.9244150957186567 0.7661417576739353 0.8921213120205098 1.0 14.595932344859255 -6.9716221748901885 24.71600279693512 0.8816691397119466 1.020974430360256 0.2084061669973709 0.1347422958432351 323.8290260496791 282041.6095284648 0.04941488440177522 0.04357898979582683 1.0675244363675303e-07 6.9716221748901885 0.13930529064830932 T(ph)TSPLEEEEREIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTSPLEEEEREIK 13 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 T(0.79)T(0.164)S(0.046)PLEEEEREIK;T(0.543)T(0.427)S(0.03)PLEEEEREIK 85.006 0.0059868000000000005 29302000.0 44945.0 20947.8 36887.0 58417.0 51868.0 60706.0 49835.0 58895.0 51209.0 41475.0 True False 52553.30079578623 23027.359144812723 37766.5259747265 55144.084880469345 41704.837737553426 57522.47049319468 45114.268025844576 57349.068654410665 51957.834747090055 48994.08918408063 1.072645734842277 0.47000280091531677 0.7708384134426927 1.1255252582261903 0.8512218194496887 1.1740695959684282 0.9208104238113544 1.1705303559974083 1.0604919003979039 1.0 15.580320087569385 -5.705570601814774 7.100788463323208 1.042490206180951 0.737648009720245 0.3535117102954136 0.16695446173087206 0.20745370971694876 21.250831962002504 0.0427275885235662 0.07391272099176195 1.969832951970606e-06 5.705570601814774 -0.30484219646070587 T(ph)TSPLEEEEREIK ddPTM_PC-9_Lapatinib_30min_R1 1 TTSPLEEEEREIK 13 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 T(0.362)T(0.362)S(0.276)PLEEEEREIK 80.507 0.0091384 10770000.0 23724.0 20230.0 24607.0 21138.0 21221.0 21473.0 15784.0 16420.0 21552.0 16986.0 True False 23385.691409551222 20183.1586779275 22583.907445766876 22692.559034300884 19972.822502091247 20554.649846007822 16601.21828829486 17182.933144157083 19124.58680737873 19922.0074675777 1.1738621947416963 1.0131086794729303 1.1336160516213698 1.13906989901656 1.0025506984974404 1.0317559552901345 0.8333105142798838 0.8625101246509241 0.9599728761523285 1.0 14.282075409364897 -6.7978871818578455 1.7549982556680637 0.9063638640818356 1.1052066770618427 0.6217655371927298 0.06585375284675678 0.22134359264040854 1.4086249778408064 0.027531912584797886 0.024453898383288857 1.5926223942092025e-07 6.7978871818578455 0.19884281298000717 T(ph)TSPPEVSGYSYEK ddPTM_PC-9_AZD4547_30min_R2 3 TTSPPEVSGYSYEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.73)T(0.135)S(0.135)PPEVSGYSYEK;T(0.921)T(0.06)S(0.019)PPEVSGYSYEK;T(0.674)T(0.133)S(0.193)PPEVS(0.001)GYSYEK 150.9 0.00058267 1014790000.0 254113.0 233273.0 299526.0 419850.0 355188.0 363794.0 279922.0 344561.0 256039.0 293139.0 True False 334915.6481212495 308673.93534785643 295554.08953318844 323060.06911783776 305876.27719116263 341045.90367036057 304834.51571923157 291317.0146740976 269572.69882602134 282876.2928345668 1.183965063898503 1.0911976124078264 1.0448174591500177 1.1420542381993513 1.08130757132782 1.2056362173475343 1.0776248255540684 1.0298389156438328 0.9529702758925587 1.0 18.109811747518926 -7.812250551137992 2.5720216203477446 0.9802721095436487 1.1193369138356408 0.612710218657205 0.04692615204684968 0.19531117337665133 2.564384587798612 0.03121631454777446 0.013170799742979617 1.540811278860273e-08 7.812250551137992 0.13906480429199208 T(ph)TSPPEVSGYSYEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTSPPEVSGYSYEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.487)T(0.026)S(0.487)PPEVSGYSYEK 88.706 0.01372 188880000.0 81925.0 73648.0 83756.0 88579.0 109380.0 90111.0 85559.0 82897.0 92443.0 79603.0 True False 95793.28440749345 80959.28671732447 85753.060686399 83616.20580699289 87947.7741908998 85385.42052865056 77454.23212648205 80721.0415866318 93794.80399002631 94034.3937629989 1.0187047586963511 0.8609539922315183 0.9119329349060101 0.8892087507655587 0.935272411204781 0.9080232998986848 0.8236798157246068 0.8584203965846623 0.9974521048800885 1.0 16.52090090906126 -8.27747676081996 23.537489500388787 0.9987261417922798 0.8982553449993413 0.38168948232215916 0.0497851645962707 440.67970242125557 646757.0377931718 0.046941072634960945 0.012315157268611498 5.278654522062568e-09 8.27747676081996 -0.10047079679293847 T(ph)TSPPEVSGYSYEK ddPTM_PC-9_Lapatinib_30min_R1 3 TTSPPEVSGYSYEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.767)T(0.116)S(0.116)PPEVSGYSYEK;T(0.692)T(0.16)S(0.147)PPEVS(0.001)GYSYEK;T(0.957)T(0.021)S(0.021)PPEVSGYSYEK 233.52 2.3359000000000002e-26 899290000.0 1090579.0 973197.0 1116217.0 1027492.0 1087488.0 1056921.0 965281.0 948808.0 994519.0 769524.0 True False 1075027.1434723071 970943.6221395461 1024445.9469822226 1103057.1892928341 1023524.0939236707 1011718.9526331866 1015258.5270237919 992893.0834738987 882505.7974706517 902535.1980737236 1.1911193555295485 1.0757958517427644 1.1350758941797423 1.2221763668021852 1.134054490182957 1.1209745113459213 1.1248963244764894 1.100115636036163 0.9778076238513239 1.0 19.783623671363166 -8.116964774947741 2.4827967025924242 0.9856195964206644 1.1425899169546363 0.7148232975241756 0.03833193693753791 0.16545428252619024 1.8312015672491904 0.033827362552274746 0.010648718498557069 7.638977398025703e-09 8.116964774947741 0.15697032053397186 T(ph)TSPPLSIPTTHLIHQPAGSR ddPTM_PC-9_AZD4547_30min_R2 1 TTSPPLSIPTTHLIHQPAGSR 21 0 Q5T5U3;A0A087WW76;A0A452Q6Z5;E7ESW5;A0A1B0GV73;Q5T5U3-3 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 T(0.333)T(0.333)S(0.333)PPLS(0.001)IPTTHLIHQPAGSR 80.835 0.0083527 19568000.0 12579.0 6539.4 20662.0 32282.0 19092.0 19795.0 11485.0 23596.0 16142.0 18678.0 True False 16578.86034054609 8653.133165063144 20388.008379689025 24839.883651928172 16441.405351908506 18557.215520747464 12507.142750606889 19949.7803821384 16995.233165453872 18024.088905140747 0.919816831119688 0.48008713287000804 1.1311533407868428 1.378149197036165 0.9121906487722198 1.0295785611362949 0.693912619740777 1.1068398789604514 0.9429177394151984 1.0 14.137638714452102 -5.274152701832223 24.98135102956186 1.0251748913918914 0.6999519642056716 0.313257558547818 0.1921177156783477 802.3057240702208 1576510.4940550327 0.051360281258312115 0.10805609639035874 5.319211981219036e-06 5.274152701832223 -0.3252229271862198 T(ph)TSPPLSIPTTHLIHQPAGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TTSPPLSIPTTHLIHQPAGSR 21 0 Q5T5U3;A0A087WW76;A0A452Q6Z5;E7ESW5;A0A1B0GV73;Q5T5U3-3 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 T(0.333)T(0.333)S(0.333)PPLS(0.002)IPTTHLIHQPAGSR;T(0.331)T(0.331)S(0.331)PPLS(0.006)IPTTHLIHQPAGSR;T(0.308)T(0.308)S(0.308)PPLS(0.072)IPT(0.003)THLIHQPAGSR 79.236 0.0021165 18045700.0 17259.6 18408.8 25443.199999999997 26068.300000000003 30240.1 30429.2 31291.7 26476.5 26017.9 19184.3 True False 20181.309387361263 20236.30400447916 26049.862381873343 24607.7776655689 24314.76948537421 28833.439184454903 28327.523643710643 25781.519929170612 26398.362566469048 22662.26172716475 0.8905249454060614 0.8929516501092365 1.149482019733624 1.0858482688897775 1.0729189247791908 1.272310748661635 1.2499866070187986 1.1376410809988518 1.1648600163692362 1.0 14.468004230987392 -5.261189752210045 8.071157912040668 1.1507809647326475 0.891060628962527 0.6311704503566444 0.0761554455425491 0.06611872673096907 49.8855489641757 0.020519585895790837 0.04816854333446121 5.4803746374008595e-06 5.261189752210045 -0.25972033577012044 T(ph)TSPPLSIPTTHLIHQPAGSR ddPTM_PC-9_Lapatinib_30min_R1 2 TTSPPLSIPTTHLIHQPAGSR 21 0 Q5T5U3;A0A087WW76;A0A452Q6Z5;E7ESW5;A0A1B0GV73;Q5T5U3-3 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 T(0.329)T(0.329)S(0.329)PPLS(0.012)IPTTHLIHQPAGSR;T(0.333)T(0.333)S(0.333)PPLS(0.002)IPTTHLIHQPAGSR 91.725 0.0041639 29894000.0 35267.0 27161.5 36130.0 28989.1 36806.0 32278.0 32388.0 33903.7 45238.0 24841.7 True False 34764.0861128243 27098.609215547578 33159.53086583319 31121.055118802702 34641.14344338015 30897.545183693055 34064.89216429889 35478.98967354195 40142.82006274126 29135.554745515412 1.1931842869123759 0.9300872920471382 1.1381122190898787 1.0681469905285705 1.1889646085668633 1.0604756097341463 1.1691863244698375 1.2177214397815073 1.377794945501084 1.0 14.830493159635227 -7.49811957301509 3.3803073099723657 1.2216642260394805 1.0938789280429044 0.1415554867963329 0.1109901732173844 0.37917330330847826 8.985851395352736 0.05164188923858174 0.03040637850668745 3.175999511709259e-08 7.49811957301509 -0.12778529799657612 T(ph)TSPSSDTDLLDR ddPTM_PC-9_AZD4547_30min_R2 1 TTSPSSDTDLLDR 13 0 Q96QT6;C9J9G2;Q96QT6-2;Q96QT6-5;Q96QT6-3;K7ENU0;K7ERZ4;K7EJ43 Q96QT6 PHF12 PHD finger protein 12 1 T(0.981)T(0.01)S(0.01)PSSDTDLLDR 228.62 2.5096999999999996e-19 12952000.0 39188.0 35508.0 39094.0 56293.0 46720.0 43886.0 31910.0 44557.0 33017.0 36379.0 True False 51648.96883896338 46985.26660321466 38575.5880164342 43315.518568180174 40233.73444590224 41141.801482370436 34749.92818213892 37671.73946800054 34762.21121445857 35105.38228290582 1.4712549894126428 1.3384063510424615 1.098851102248733 1.2338711545457857 1.1460844984301344 1.1719513877051264 0.9898746551767368 1.0731043793915436 0.9902245454648032 1.0 15.099404617987272 -1.5228787452807522 0.3083812203939539 1.0046808643073275 5.135049850739412 0.8309679312596429 0.0621361295084641 22.197260060810642 0.31687339423462385 0.06294660085667168 51.055700519847434 0.02999999999997136 1.5228787452807522 4.130368986432084 T(ph)TSPSSDTDLLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTSPSSDTDLLDR 13 0 Q96QT6;C9J9G2;Q96QT6-2;Q96QT6-5;Q96QT6-3;K7ENU0;K7ERZ4;K7EJ43 Q96QT6 PHF12 PHD finger protein 12 1 T(0.689)T(0.118)S(0.07)PS(0.06)S(0.06)DT(0.002)DLLDR 76.32600000000001 0.042460000000000005 11641000.0 10934.0 16537.0 15401.0 16594.0 20692.0 13584.0 13583.0 15674.0 20639.0 13300.0 True False 12784.910243656177 18178.68407077441 15768.21824861776 15664.291978473868 16637.55113876485 12871.631126734692 12296.319907595998 15262.57410797576 20940.806329848096 15711.184717257927 0.8137457788025757 1.1570536785049736 1.0036301228956455 0.9970153276390067 1.0589622258396185 0.8192654696877103 0.7826475296983253 0.9714464174818471 1.3328597878965613 1.0 13.939504352114712 -8.119346848955084 9.012741172941853 1.16526752141262 0.9532128816024432 0.2948007300785698 0.13382844451985504 0.4185306234238304 29.309599186146773 0.09170688612223467 0.034538969656524 7.597192853608391e-09 8.119346848955084 -0.2120546398101768 T(ph)TSRSPVLSR ddPTM_PC-9_AZD4547_30min_R2 1 TTSRSPVLSR 10 1 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;H7C3Z6;O95819-6;E7EN19 C9J840;O95819-6;E7EN19 MAP4K4 1 T(0.958)T(0.03)S(0.011)RSPVLSR 63.091 0.040846 5535000.0 8510.4 10685.0 11469.0 19867.0 16773.0 11934.0 10308.0 14506.0 11740.0 12162.0 True False 11216.530172683317 14138.717293436644 11316.913566288527 15286.970092090245 14444.35847305477 11187.765093437745 11225.392030758007 12264.431014718582 12360.552432314971 11736.2120818247 0.9557197922533975 1.2047087420422973 0.96427309658237 1.3025471920164455 1.230751316723736 0.953268824339302 0.9564748789894675 1.0450076165300308 1.0531977733648112 1.0 13.518679226449821 -6.774012268545668 24.997967648424464 1.0015831046791135 1.135862757378012 0.27290171952173015 0.10599204750775715 315.65684123058446 627598.9804832481 0.03761989551981901 0.03340072434931524 1.68262652725911e-07 6.774012268545668 0.13427965269889852 T(ph)TSRSPVLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TTSRSPVLSR 10 1 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;H7C3Z6;O95819-6;E7EN19 C9J840;O95819-6;E7EN19 MAP4K4 1 T(0.622)T(0.189)S(0.189)RSPVLSR;T(0.333)T(0.333)S(0.333)RSPVLSR;T(0.431)T(0.431)S(0.137)RS(0.001)PVLSR 72.73100000000001 0.021478999999999998 134316000.0 55101.0 56232.0 68467.0 76622.0 98259.0 89454.0 74711.0 74531.0 67003.0 56521.0 True False 64428.51100564283 61814.34133565861 70099.51294254357 72329.1177518758 79005.85430813323 84762.87476523303 67633.83321920094 72574.64022212221 67982.79211777759 66767.80988001017 0.9649636721861726 0.9258105282582498 1.0498998404848217 1.0832932498738534 1.183292584407311 1.2695170759316827 1.0129706716567028 1.0869705079820293 1.0181971258298106 1.0 16.02686509722426 -5.45755983979713 2.6861176011181853 1.104657672356057 0.9442451792329543 0.3472847841386524 0.07877240399233919 0.3021255484869788 4.235492355042878 0.023253435551473897 0.05600230723898509 3.4869053607251093e-06 5.45755983979713 -0.1604124931231028 T(ph)TT(ph)ES(ph)VQEQY(ph)T(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 TTTESVQEQYTK 12 0 P30968-2 P30968-2 5 T(0.504)T(0.504)T(0.993)ES(0.998)VQEQY(1)T(1)K 50.148999999999994 0.030916000000000003 21471000.0 17481.0 19968.0 18883.0 19059.0 16369.0 15340.0 18122.0 18078.0 21202.0 11589.0 True False 17231.71773437722 19921.76532283027 17330.5126304879 20460.662438960204 15406.207602692219 14683.94395928654 19060.268488373003 18917.969876983676 18814.007493042132 13592.143208628158 1.2677704663557912 1.4656824179268602 1.2750389960198965 1.5053301105576917 1.133464190762242 1.0803258716377648 1.4023004463544597 1.3918312650630944 1.3841825534253631 1.0 13.73048533769108 -11.037235805578115 2.767461787985236 0.9853950895358873 1.3226985976677779 0.35761952459202795 0.1298219705429532 13538014.276889358 14043173.671950132 1490090.3823468194 0.03393206860504697 9.178341117462023e-12 11.037235805578115 0.3373035081318906 T(ph)TTLSGTAPAAGVVPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTTLSGTAPAAGVVPSR 17 0 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 T(0.96)T(0.023)T(0.01)LS(0.005)GT(0.001)APAAGVVPSR;T(0.743)T(0.002)T(0.234)LS(0.006)GT(0.016)APAAGVVPSR 125.33 5.8497e-05 0.0 22384.9 16883.2 19575.3 22108.6 31655.0 26416.0 23580.7 23871.0 14844.9 19075.3 True False 26174.221448071996 18559.25251881831 20042.04939173866 20869.926819048298 25452.429987318832 25030.698457289727 21346.96538651615 23244.41154341518 15061.978578708375 22533.500890008272 1.1615692375470197 0.8236293423472333 0.8894334479834706 0.9261732973016354 1.1295373103166966 1.11082155318301 0.9473434905084699 1.0315490547552748 0.6684260316330654 1.0 14.459783853099891 -8.222735817237325 24.98721131016577 0.8342125932322594 0.996236970574266 0.21640512906992226 0.12765220972230507 736.2719175754811 475342.0790715896 0.08614858374582747 0.03255980501884568 5.987757215415042e-09 8.222735817237325 0.1620243773420066 T(ph)TTPPDSGVLFEGLGISTRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTTPPDSGVLFEGLGISTRPR 21 1 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 T(0.364)T(0.364)T(0.271)PPDSGVLFEGLGISTRPR;T(0.405)T(0.124)T(0.405)PPDS(0.067)GVLFEGLGISTRPR 122.29 1.0409e-06 11381700.0 32754.0 35137.0 39199.0 47900.0 39004.0 45765.0 42762.0 42080.0 41549.0 34772.0 True False 38298.60527901174 38625.169147656794 40133.65282303533 45216.31829389529 31361.44619255676 43365.00283532191 38711.27378993007 40975.44458744542 42156.57552201459 41075.88834499947 0.9323865367764874 0.9403367937715942 0.9770611042164145 1.1007995229249832 0.7635001324657819 1.055728910135698 0.942433027005799 0.9975546783867358 1.0263095265996038 1.0 15.326004156114125 T(ph)TTPPDSGVLFEGLGISTRPR ddPTM_PC-9_Lapatinib_30min_R1 1 TTTPPDSGVLFEGLGISTRPR 21 1 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 T(0.364)T(0.364)T(0.271)PPDS(0.001)GVLFEGLGISTRPR 101.54 0.00012009 5843600.0 15718.0 14083.0 15930.0 12010.0 23686.0 21680.0 27054.0 24243.0 25249.0 18826.0 True False 15493.858437671819 14050.391678756934 14620.296891578264 12893.255464185528 22292.836048467692 20752.7969385484 28454.72374376133 25369.41828342267 22405.191736242843 22080.049015931803 0.7017130454054819 0.636338790218215 0.6621496574137596 0.5839323750994588 1.0096370724712773 0.9398890792123817 1.2887074536487622 1.1489747266918398 1.0147256339909587 1.0 14.430455754335968 -6.427987148554563 2.3163567002163865 1.1039828835354508 0.6434136657073427 0.8130858409563749 0.09812614423518039 0.12275182111983207 1.2976771607091522 0.03438600401641383 0.03929005245572389 3.732612030086123e-07 6.427987148554563 -0.4605692178281081 T(ph)TTSPFFSEDTFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTTSPFFSEDTFR 13 0 A0A494C0H4;H0Y9M2;Q17R98-2;Q17R98;A0A5F9ZGT0;H0Y9K9;G5E9Z1;A0A590UJE4;Q17R98-3;A0A5F9ZHK5 A0A494C0H4 ZNF827 Zinc finger protein 827 1 T(0.739)T(0.12)T(0.12)S(0.021)PFFSEDTFR 151.66 0.00033006 6760900.0 39204.0 50619.0 50336.0 66184.0 65843.0 54403.0 47581.0 50649.0 54775.0 42744.0 True False 45840.46288570484 55644.1197906833 51536.201140343066 62475.92505142309 52941.53680793035 51550.01090899204 43073.783223391394 49319.51741705143 55575.98075088085 50493.148838682144 0.9078551039103954 1.1020132645808585 1.0206573035283126 1.2373148929773439 1.048489508488972 1.0209308013981542 0.8530619344221434 0.976756620479735 1.1006637935858898 1.0 15.623800028661572 -6.857681470658691 3.771868078240978 0.976286053977697 1.0730876802622784 0.12996378029531352 0.0949065825294253 0.416664997820858 11.31924928723815 0.035367918834676985 0.03130433140788266 1.3877733054169473e-07 6.857681470658691 0.09680162628458144 T(ph)VATPLNQVANPNSAIFGGARPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVATPLNQVANPNSAIFGGARPR 23 1 Q15056;Q15056-2 Q15056;Q15056-2 EIF4H Eukaryotic translation initiation factor 4H 1 T(0.579)VAT(0.421)PLNQVANPNSAIFGGARPR 100.95 3.7175e-06 23518000.0 20275.0 16827.0 22946.0 25464.0 25905.0 25721.0 19618.0 21874.0 23160.0 18486.0 True False 23707.15705049654 18497.473354231177 23493.119663189584 24037.33463540188 20829.101210598463 24372.145480767304 17759.6410179797 21299.830677418755 23498.67118558468 21837.36546490451 1.085623496506345 0.8470560876017313 1.0758220674992176 1.1007433416834558 0.953828484671081 1.1160753580800082 0.8132684799602661 0.9753846319809208 1.0760762887515027 1.0 14.414511194599305 T(ph)VFGITTVLTMT(ph)T(ph)LSISARHSLPK ddPTM_PC-9_AZD4547_30min_R2 1 TVFGITTVLTMTTLSISARHSLPK 24 1 E7EV53;Q16445;P48169 E7EV53 GABRA6;GABRA4 Gamma-aminobutyric acid receptor subunit alpha-6;Gamma-aminobutyric acid receptor subunit alpha-4 3 T(0.716)VFGIT(0.174)T(0.176)VLT(0.211)MT(0.565)T(0.554)LS(0.239)IS(0.182)ARHS(0.182)LPK 41.521 0.031643 12501000.0 27456.0 26522.0 32433.0 29552.0 28518.0 41691.0 42556.0 43268.0 40862.0 32444.0 True False 36186.43687972282 35094.71783402216 32002.917228654245 22739.242973848643 24558.767956511998 39084.05517936257 46343.40155810419 36581.92479972727 43021.88189857362 31308.145435185015 1.1558154076752 1.1209452794537513 1.0221914068627145 0.7263043740781149 0.7844210385234806 1.2483669868046148 1.4802346454549846 1.1684475171312902 1.3741434154136887 1.0 14.934250431280427 -6.861555109968493 7.666225983114856 1.2822896903081298 0.9616744462832424 0.4170647639638919 0.1715117662710557 0.2335020758726351 15.795426592503057 0.06380322714928849 0.05631310199810722 1.3754502609008523e-07 6.861555109968493 -0.3206152440248874 T(ph)VFSPTLPAAR ddPTM_PC-9_AZD4547_30min_R2 4 TVFSPTLPAAR 11 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 T(0.984)VFS(0.01)PT(0.007)LPAAR;T(0.638)VFS(0.121)PT(0.241)LPAAR;T(0.969)VFS(0.024)PT(0.006)LPAAR;T(0.963)VFS(0.029)PT(0.008)LPAAR 167.11 0.0017305 355418000.0 343433.0 482179.0 533619.0 754260.0 609301.0 610141.0 608954.0 809900.0 474904.0 481633.0 True False 452637.55014983466 638033.9322257368 526542.8633995389 580377.0102008347 524710.0734508281 571988.7868170951 663149.7262997869 684748.5646505312 500006.4559042681 464771.1752676749 0.9738933355519473 1.3727915287738637 1.132907743463841 1.2487371013630075 1.1289643191590628 1.2306890299030928 1.4268305815606146 1.4733025649797775 1.0758121039160833 1.0 18.82616107117431 -7.004377371161594 24.201088209807967 1.2899041335262686 1.1842985758596265 0.011226050153069989 0.16489961196448819 329.24688352876126 1820310.1480689005 0.05659456702866824 0.04866608655441858 9.899713560220011e-08 7.004377371161594 -0.10560555766664215 T(ph)VFSPTLPAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TVFSPTLPAAR 11 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 T(0.995)VFS(0.001)PT(0.003)LPAAR;T(0.478)VFS(0.25)PT(0.272)LPAAR;T(0.982)VFS(0.011)PT(0.006)LPAAR 179.94 0.0045527 226599000.0 300532.0 414040.0 432506.0 472887.0 523410.0 547530.0 627430.0 649407.0 466878.0 351088.0 True False 351406.1318224327 455143.1549049667 442818.5833281385 446392.6745103403 420851.56783012254 518816.56292852206 567995.2882001749 632360.7543535928 473705.20750360144 414737.4751889221 0.8472977554351929 1.097424713543523 1.0677081523111092 1.0763258717023307 1.0147420790426893 1.2509517320376937 1.3695296957224339 1.5247253797490532 1.1421808634192467 1.0 18.661838887792342 -6.827808419611878 4.4040258717504015 1.3032981355619113 1.0299683670781996 0.3805273050206073 0.14620403783359173 0.19893571777979777 7.544725176770539 0.051023543881968475 0.04562585743811955 1.486591277893222e-07 6.827808419611878 -0.2733297684837117 T(ph)VFSPTLPAAR ddPTM_PC-9_Lapatinib_30min_R1 4 TVFSPTLPAAR 11 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 T(0.813)VFS(0.047)PT(0.14)LPAAR;T(0.902)VFS(0.056)PT(0.042)LPAAR;T(0.865)VFS(0.061)PT(0.075)LPAAR;T(0.999)VFS(0.001)PTLPAAR 199.8 0.00014602 294366000.0 656409.0 742248.0 684900.0 658359.0 663035.0 680777.0 723564.0 780206.0 707280.0 516800.0 True False 647048.4872893322 740529.3703595818 628590.1657904561 706776.9170812438 624036.584876965 651661.7546786967 761026.6034941581 816457.2190420366 627618.6784114159 606128.1914072856 1.0675109596652144 1.2217372180631436 1.037058125164941 1.1660518799501403 1.029545554428182 1.0751220021060115 1.2555538816421576 1.3470041991388273 1.0354553497243453 1.0 19.209263419206643 -7.243703072066193 24.688149130097333 1.1884203818425776 1.1020668166465877 0.042509440340227744 0.10880118025029394 1477.5817381860418 2056729.9265774405 0.040330049804385266 0.031163738302848118 5.7055422793093756e-08 7.243703072066193 -0.08635356519598991 T(ph)VHPNSPGIPYR ddPTM_PC-9_AZD4547_30min_R2 1 TVHPNSPGIPYR 12 0 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;F8VWY3;C9J102;C9JNI4 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 T(1)VHPNSPGIPYR 103.08 0.004626600000000001 8772800.0 34635.0 40778.0 45699.0 77366.0 54133.0 49012.0 41143.0 61769.0 52537.0 50653.0 True False 45648.20954724651 53958.691042747734 45093.00140080387 59530.46399278472 46617.567353596445 45947.27189203709 44804.647295447925 52224.02036041312 55313.99856358877 48879.65388757328 0.9338897867861478 1.1039090245372156 0.9225311108896356 1.2178986399885128 0.9537213062273354 0.9400081268521074 0.9166318443764319 1.0684204204991328 1.1316364614777132 1.0 15.576946449148615 -7.96498087822796 24.841508474405032 1.0772218778526783 1.0031746113989863 0.09403282287412784 0.09508261752721707 365.49563665282915 259271.31059743013 0.05152128100620145 0.02474992264889674 1.0839746398397875e-08 7.96498087822796 -0.07404726645369197 T(ph)VHPNSPGIPYR ddPTM_PC-9_Lapatinib_30min_R1 1 TVHPNSPGIPYR 12 0 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;F8VWY3;C9J102;C9JNI4 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 T(0.945)VHPNS(0.055)PGIPYR 91.845 0.012967 7613000.0 42761.0 39871.0 45364.0 28679.0 37014.0 33362.0 34688.0 30703.0 41082.0 31925.0 True False 42151.22029859301 39778.68114916695 41634.34703010397 30788.149330339456 34836.9092923239 31935.18503062044 36483.97491031245 32129.57346681213 36454.91254736142 37443.19371261145 1.1257378476343973 1.0623741514808036 1.111933649401303 0.8222629075566684 0.9303936400219591 0.8528969317022809 0.9743820249506141 0.8580884876812842 0.9736058528330834 1.0 15.192415874215442 -5.747124574975833 24.999998851102426 0.9104437760043899 1.0962511865045628 0.6850935942227108 0.0570854879999287 122.64925600657082 214198.20378362553 0.014307510228904906 0.024636688874136645 1.7900923022843325e-06 5.747124574975833 0.1858074105001729 T(ph)VLAMDFMVFT(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 1 TVLAMDFMVFTLR 13 0 A0A0C4DGF4;E9PQF7;E9PRW0;Q9NZQ8-3;Q9NZQ8;Q9NZQ8-2 A0A0C4DGF4 TRPM5 Transient receptor potential cation channel subfamily M member 5 2 T(1)VLAMDFMVFT(1)LR 69.878 0.007926899999999999 24139000.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1670.7 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1482.5281727490567 0.0 0.0 T(ph)VLRQRS(ph)RS(ph)LS(ph)S(ph)SGTK ddPTM_PC-9_Lapatinib_30min_R1 2 TVLRQRSRSLSSSGTK 16 3 Q9NZJ5 Q9NZJ5 EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 5 T(0.999)VLRQRS(0.998)RS(0.965)LS(0.878)S(0.558)S(0.558)GT(0.043)K;T(1)VLRQRS(1)RS(0.949)LS(0.877)S(0.514)S(0.514)GT(0.146)K 51.771 0.028367000000000003 6202600.0 22694.4 22426.0 26545.0 19880.5 23673.0 26831.0 20650.7 18668.5 27751.0 20422.8 True False 22370.773694356743 22374.073974849347 24362.57256666321 21342.578289403868 22280.600682908716 25683.500676115855 21719.892201348874 19535.90666270989 24625.39014901481 23952.85376832956 0.9339502470446907 0.9340880293951581 1.0171052185387353 0.8910244472674484 0.9301856429469838 1.0722522219909576 0.9067768046105176 0.8155982937006131 1.0280775053857873 1.0 14.547909929963861 -10.338330546060824 22.037193505122445 0.9999999999803927 0.9457119379733262 0.04647958284103193 0.07060047862537576 0.0 0.0 0.06808103925469172 0.016512077408759783 4.588486454093145e-11 10.338330546060824 -0.054288062007066484 T(ph)VPSTPTLVVPHR ddPTM_PC-9_Lapatinib_30min_R1 1 TVPSTPTLVVPHR 13 0 P12270 P12270 TPR Nucleoprotein TPR 1 T(0.912)VPS(0.058)T(0.03)PTLVVPHR 205.12 2.162e-09 16432000.0 13509.0 16604.0 28248.0 30121.0 72405.0 117990.0 106760.0 116510.0 119520.0 110320.0 True False 13316.359182752813 16565.554458146715 25925.558480433323 32336.198820710426 68146.28025370704 112943.84274812383 112287.51041930809 121923.47994066615 106058.39899860384 129388.66500783978 0.10291750967479231 0.12802941012756405 0.20036962649597218 0.24991523653753708 0.5266789038249834 0.8729036870523431 0.8678311227069581 0.9423041804572193 0.8196884865623867 1.0 16.981351711139332 -6.473346554515204 1.5412912045435878 0.9138753369551947 0.13627202522485915 0.9788254763610389 0.05084190405696218 0.04821005352405188 0.23226227655800866 0.01941457832528095 0.022272144774938617 3.362431499240108e-07 6.473346554515204 -0.7776033117303356 down T(ph)VPT(ph)TIMAGIVT(ph)PFVGTTAFSPLS(ph)SK ddPTM_PC-9_AZD4547_30min_R2 1 TVPTTIMAGIVTPFVGTTAFSPLSSK 26 0 Q8IZF6;Q8IZF6-3;Q8IZF6-2 Q8IZF6 GPR112 Probable G-protein coupled receptor 112 4 T(0.67)VPT(0.65)T(0.65)IMAGIVT(0.718)PFVGT(0.11)T(0.11)AFS(0.113)PLS(0.856)S(0.124)K 49.902 0.0070461 14496000.0 37292.0 37026.0 44675.0 61036.0 54570.0 59940.0 42858.0 45441.0 45053.0 48426.0 True False 49150.08027821331 48993.93041710672 44082.58030987358 46965.09319679974 46993.89744676554 56191.94232450634 46672.278973052664 38419.13758029969 47434.40960247758 46730.62047972726 1.0517746131690175 1.04843312402328 0.9433339394454979 1.00501753913527 1.0056339283393958 1.2024651448590031 0.998751535800816 0.822140540525601 1.0150605559165566 1.0 15.512080572692298 -7.530694422285704 24.938944532759503 0.9332495187823215 1.0405670901236614 0.2299186791608253 0.07863251409997109 249.75383518332697 796922.6219904858 0.03724238087343498 0.021555371397100676 2.9464941129226484e-08 7.530694422285704 0.1073175713413399 T(ph)VS(ph)LLALIMAY(ph)QR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVSLLALIMAYQR 13 0 B4E0F6;K7EIT8;E7EVE9;A8MX75;P18074-2;P18074 B4E0F6 ERCC2 TFIIH basal transcription factor complex helicase XPD subunit 3 T(1)VS(1)LLALIMAY(1)QR 59.155 0.042986 1602400.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 T(ph)VSDNSLSNSR ddPTM_PC-9_AZD4547_30min_R2 1 TVSDNSLSNSR 11 0 H0Y7W6;B7ZL14;Q96RU3-4;Q96RU3-3;Q96RU3-5;Q96RU3-2;Q96RU3 H0Y7W6;Q96RU3-5 FNBP1 Formin-binding protein 1 1 T(0.989)VS(0.011)DNSLSNSR 158.86 0.0025074999999999997 85333000.0 17233.0 17354.0 20635.0 21003.0 30646.0 22029.0 18510.0 26684.0 18496.0 18627.0 True False 22712.735531332444 22963.34112403367 20361.366417330508 16161.082843115284 26391.331888465753 20651.523147590087 20157.354141378633 22560.600937319105 19473.660799667607 17974.874399617536 1.2635824332555958 1.2775244273485593 1.1327682166037139 0.8990929496263492 1.468234564633581 1.1489105675213789 1.1214183583840527 1.255118697118637 1.0833823016911852 1.0 14.133694069341589 -8.496881515835327 4.749328652291984 1.000323079097197 1.1911498974512604 0.17897665176164368 0.1374899402702133 0.2914874129457776 18.475404119134385 0.13182466346972516 0.03434633823546956 3.1850663525960746e-09 8.496881515835327 0.19082681835406334 T(ph)VSDNSLSNSR ddPTM_PC-9_Lapatinib_30min_R1 2 TVSDNSLSNSR 11 0 H0Y7W6;B7ZL14;Q96RU3-4;Q96RU3-3;Q96RU3-5;Q96RU3-2;Q96RU3 H0Y7W6;Q96RU3-5 FNBP1 Formin-binding protein 1 1 T(0.989)VS(0.011)DNS(0.001)LSNSR;T(0.694)VS(0.004)DNS(0.302)LSNSR 161.87 0.00033698 111954000.0 30178.1 39434.2 53368.0 38001.0 47087.0 44550.0 38795.0 32347.1 48752.0 37232.0 True False 29747.754760014242 39342.89253273004 48980.28904643747 40795.72030761985 44317.43523660385 42644.70035112226 40803.615274607146 33850.06435489426 43261.03637868078 43667.50159147846 0.6812332667509285 0.9009650449158659 1.1216645620045225 0.9342352738490762 1.0148836920235487 0.9765775186791131 0.9344160711628579 0.7751774917551034 0.9906918143245227 1.0 15.414272370143342 -4.802195081213361 4.01025755329724 0.9626285166129357 0.6623013842385361 0.521221399083259 0.08226206415654284 0.18153847250095959 5.356612323513878 0.02152557215070767 0.15030834962471978 1.5769027799030755e-05 4.802195081213361 -0.30032713237439956 T(ph)VSEPNLK ddPTM_PC-9_AZD4547_30min_R2 2 TVSEPNLK 8 0 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;F8VWY3;H0YI41;C9JEB6;C9JAH2;C9JF80 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 T(0.993)VS(0.007)EPNLK;T(0.906)VS(0.094)EPNLK 112.3 0.0091256 108709000.0 361810.0 327890.0 399950.0 466590.0 522010.0 525920.0 427520.0 441390.0 413560.0 424300.0 True False 476858.05388448853 433874.03026157594 394646.4016773122 359024.88424363965 449537.9220484902 493034.13926099986 465568.45178401854 373183.31763316185 435419.9373005263 409445.3861468687 1.164643857321276 1.0596627656366964 0.963856023366574 0.8768565879378523 1.0979191297743438 1.2041511662904605 1.1370709441014886 0.9114361286252238 1.0634383779436227 1.0 18.643311505327226 T(ph)VSEPNLK ddPTM_PC-9_Lapatinib_30min_R1 2 TVSEPNLK 8 0 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;F8VWY3;H0YI41;C9JEB6;C9JAH2;C9JF80 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 T(0.999)VS(0.001)EPNLK;T(0.985)VS(0.015)EPNLK 114.97 0.0089351 107988000.0 500880.0 411900.0 428730.0 425040.0 508860.0 439870.0 409037.0 413480.0 515620.0 430352.0 True False 493737.35934985644 410946.27085706004 393481.4743456589 456298.8594918757 478929.85525725194 421057.78548705165 430214.93442658754 432691.790282952 457545.4458806896 504737.7697920049 0.9782056919443901 0.8141777680445927 0.7795760450180039 0.9040315324131772 0.9488686678918679 0.834210971888558 0.852353360842944 0.8572605740625633 0.906501302783894 1.0 18.945174522739094 -8.64195966537384 3.138129574378163 0.999943564655665 0.8682035504214733 0.31872835109135167 0.056764747907216105 0.6128641346198039 12.68482171018075 0.05578477180414517 0.014799942977228111 2.2805538661172605e-09 8.64195966537384 -0.13174001423419168 T(ph)VSFEALPIMR ddPTM_PC-9_AZD4547_30min_R2 1 TVSFEALPIMR 11 0 O15084-2;O15084;O15084-4;O15084-1 O15084-2 ANKRD28 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A 1 T(0.936)VS(0.064)FEALPIMR 118.77 0.0025215 2779700.0 9342.2 14386.0 17926.0 24064.0 20749.0 21234.0 17034.0 21689.0 17788.0 18280.0 True False 12312.825270168512 19035.99316643703 17688.28952735967 18516.41658509385 17868.359503810494 19906.234623266064 18549.99300076949 18337.46341363791 18728.23736507827 17640.022763998964 0.698005066937749 1.0791365420053234 1.0027362075438593 1.0496821252908752 1.0129442429222675 1.1284698942618232 1.0515855477594767 1.039537400771519 1.061690090519623 1.0 14.106564802207197 -4.758429554312029 24.999963176374912 1.0488219386028348 0.6980045905424724 0.8918223319264895 0.03649335039239037 24.258652129052717 201459.67220364098 0.008834035609746134 0.060722476135853125 1.7440962394742884e-05 4.758429554312029 -0.35081734806036236 T(ph)VSFEALPIMR ddPTM_PC-9_Lapatinib_30min_R1 1 TVSFEALPIMR 11 0 O15084-2;O15084;O15084-4;O15084-1 O15084-2 ANKRD28 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A 1 T(0.847)VS(0.153)FEALPIMR 123.35 0.0011654000000000002 0.0 3560.0 3685.6 3534.3 2708.1 2509.9 2607.4 3413.7 2354.2 4720.4 3811.7 True False 3509.2337471759565 3677.066219642588 3243.723496792534 2907.2627079567706 2362.272616653258 2495.8875801462664 3590.444682637616 2463.5847264296362 4188.738843984347 4470.547266229005 0.784967373834762 0.8225091919773541 0.7255763788241253 0.6503147231925152 0.5284079277045385 0.5582957592240372 0.8031331442931432 0.5510700546753684 0.9369633278740908 1.0 12.12623573574554 -8.39302229906329 5.446151942709875 0.9956224662053825 0.6793002671899487 0.5660362249109856 0.1022231333943717 0.17094402272081868 6.3872127531506795 0.10543630417637717 0.027416164325455326 4.04555119083045e-09 8.39302229906329 -0.3163221990154338 T(ph)VSPGSVSPIHGQGQVVENLK ddPTM_PC-9_Lapatinib_30min_R1 1 TVSPGSVSPIHGQGQVVENLK 21 0 A0A087WVF7;Q9NZM3-4;Q9NZM3-3;Q9NZM3-2;Q9NZM3 A0A087WVF7 ITSN2 Intersectin-2 1 T(0.488)VS(0.488)PGS(0.013)VS(0.012)PIHGQGQVVENLK 74.748 0.0031962 3405700.0 11924.0 9961.2 19792.0 13600.0 17750.0 16943.0 12020.0 15589.0 18016.0 11514.0 True False 11753.96157340621 9938.13545341431 18164.778159329384 14600.189368270041 16705.979897842673 16218.387386062062 12642.336785688305 16313.321850442428 15986.848363109475 13504.179558559385 0.8703943488337409 0.7359303399602088 1.3451226770615592 1.081160784700613 1.2370969910018623 1.20099020571615 0.9361795532165583 1.2080202117945416 1.1838444752444435 1.0 13.72111837165453 -5.248220064350932 24.992102511100356 1.1514533035125671 0.8031623022586345 0.586713495303011 0.11610677704514288 508.0477525110146 960498.1706448903 0.02849604959219208 0.07440973772900474 5.646507842180737e-06 5.248220064350932 -0.34829100125393264 T(ph)VSPPTVCTIPTVVGR ddPTM_PC-9_AZD4547_30min_R2 3 TVSPPTVCTIPTVVGR 16 0 A0A0C4DH56;Q9BWT3-2;Q9BWT3 A0A0C4DH56 PAPOLG Poly(A) polymerase gamma 1 T(0.819)VS(0.176)PPT(0.005)VCTIPTVVGR;T(0.999)VS(0.001)PPTVCTIPTVVGR;T(0.998)VS(0.002)PPTVCTIPTVVGR 148.85 4.3766e-05 21041500.0 38383.7 33205.5 46976.0 60582.0 48822.0 49607.0 39119.9 57751.0 37263.0 41398.1 True False 50588.91816944265 43938.528506056195 46353.06754642688 46615.7558825696 42043.90802906333 46505.06644797774 42601.49531471191 48826.90993595845 39232.64610607776 39948.76511960098 1.2663449800760185 1.0998720079209063 1.1603129009783486 1.1668885319235422 1.0524457490285315 1.16411774703794 1.0664033090176637 1.2222382792003095 0.9820740638320292 1.0 15.28586328737447 -1.5228787452805579 0.018029221975780302 1.1750542244515992e-09 2.5229921598765226 0.38604223409178384 0.06958528522158626 4221.936064148603 5.892884265023941 315.14949083449386 536.6396184629274 0.029999999999984782 1.5228787452805579 2.5229921587014683 T(ph)VSPPTVCTIPTVVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TVSPPTVCTIPTVVGR 16 0 A0A0C4DH56;Q9BWT3-2;Q9BWT3 A0A0C4DH56 PAPOLG Poly(A) polymerase gamma 1 T(1)VSPPTVCTIPTVVGR;T(1)VSPPTVCTIPTVVGR;T(0.985)VS(0.008)PPT(0.006)VCTIPT(0.001)VVGR 210.02 1.4772e-63 8194000.0 44594.0 57551.0 47819.0 51321.0 53281.0 49090.0 51327.0 39252.0 41909.0 44630.0 True False 52142.88342835227 63264.28293869128 48959.18631456736 48445.65075492692 42840.970530858795 46515.633981993946 46464.93498469998 38221.67659093176 42521.83984096147 52721.065709114424 0.9890331829794139 1.199981109785384 0.9286456116933784 0.9189049975245783 0.812596823577723 0.8822969216639397 0.8813352757523473 0.7249792104320834 0.8065436323987337 1.0 15.686091912978016 -5.558869491936292 2.3849358546196595 0.8461641591675682 1.093891756445173 0.5226712408444703 0.08592577320690972 0.20559687718752803 2.3312908657456433 0.023873661618643863 0.05399505672030378 2.7614075508721416e-06 5.558869491936292 0.24772759727760474 T(ph)VSPPTVCTIPTVVGR ddPTM_PC-9_Lapatinib_30min_R1 3 TVSPPTVCTIPTVVGR 16 0 A0A0C4DH56;Q9BWT3-2;Q9BWT3 A0A0C4DH56 PAPOLG Poly(A) polymerase gamma 1 T(0.592)VS(0.408)PPTVCTIPTVVGR;T(0.553)VS(0.11)PPT(0.323)VCT(0.014)IPTVVGR;T(0.617)VS(0.242)PPT(0.134)VCT(0.007)IPTVVGR 116.87 0.0011043 17152900.0 36697.0 33422.2 36130.8 33182.0 35844.9 40260.8 30762.3 32711.8 34560.0 26571.5 True False 36173.69405059439 33344.81294935385 33160.26509292129 35622.31497190711 33736.573455784855 38538.93943650872 32355.021372910076 34231.70964829705 30667.488867066153 31164.348370701802 1.16073962530216 1.0699666347171868 1.0640448726370897 1.14304700191955 1.0825374256020464 1.2366354970136295 1.0382062537629584 1.0984253301596043 0.9840567979241704 1.0 14.92760892665777 -8.095048843205532 1.7298851497870904 0.9896964984297789 1.1165384108269212 0.43179668965805507 0.054606213058796864 0.3580861027314485 1.9108008393367613 0.048101141920478624 0.01520236060839318 8.034357581899949e-09 8.095048843205532 0.12684191239714226 T(ph)VSPSTIR ddPTM_PC-9_Lapatinib_30min_R1 1 TVSPSTIR 8 0 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 T(0.766)VS(0.23)PS(0.004)TIR 83.78299999999999 0.035616 18222000.0 43035.0 53218.0 53371.0 54119.0 48371.0 44478.0 42282.0 49476.0 51571.0 28965.0 True False 42421.31300834756 53094.77699070419 48983.04239801781 58099.09179569164 45525.912881045 42575.77962328207 44471.1550725851 51774.83558101805 45762.5309132948 33971.56165656352 1.2487301419112564 1.5629183470417805 1.4418837406773726 1.7102272890203305 1.3401183419617422 1.2532770808037363 1.3090700840358038 1.5240640422844625 1.3470835216800576 1.0 15.052039919297162 -6.48817150016168 24.58078887736544 1.3181673674598473 1.496651680526071 0.25240967249516666 0.1622417937657439 774.1206922191437 548257.4758162923 0.049126656897074565 0.05567315167047604 3.2495894779852333e-07 6.48817150016168 0.1784843130662237 T(ph)VSSPIPYTPSPSSSR ddPTM_PC-9_AZD4547_30min_R2 1 TVSSPIPYTPSPSSSR 16 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 T(0.629)VS(0.341)S(0.03)PIPYTPSPSSSR 225.21 3.0667999999999998e-28 28386000.0 23742.0 28730.0 30450.0 25423.0 28722.0 32643.0 32911.0 39468.0 33520.0 23839.0 True False 31291.462135721882 38016.41065422882 30046.21310432346 19562.120131434553 24734.446077808316 30601.82804969736 35840.01524294499 33369.12748441427 35291.798767563705 23004.403866026874 1.3602379056617684 1.6525709979545187 1.3061070080018895 0.8503641409427731 1.075204826947782 1.3302595549928784 1.557963225288088 1.4505538886706 1.5341322893258267 1.0 14.489622450610467 -7.0025759871594975 24.688235001251417 1.4261946480641738 1.2473980594617666 0.05757407731998665 0.2405992241028128 227.0892413802388 2176447.168393527 0.09260493701907688 0.08023864538200147 9.940861265672709e-08 7.0025759871594975 -0.1787965886024072 T(ph)VSSPIPYTPSPSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVSSPIPYTPSPSSSR 16 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 T(0.63)VS(0.35)S(0.018)PIPYT(0.001)PSPSSSR 76.311 0.045357999999999996 0.0 8353.0 9798.6 8024.4 10557.0 16191.0 12879.0 13943.0 15688.0 14507.0 13928.0 True False 9766.997920729835 10771.340251308582 8215.732128706464 9965.525516255797 13018.489778066007 12203.60256781627 12622.218101421702 15276.206622809992 14719.137430452372 16453.03614601266 0.5936289104364993 0.654671888867088 0.4993444404908526 0.6056952302187041 0.7912515150719459 0.741723439948424 0.7671664967733421 0.9284734128850821 0.8946152734259634 1.0 14.006066214489898 -7.195635631182469 0.5531925690254895 0.991885379427451 0.5642816934905966 0.8529095898178574 0.05872645002569619 0.33065419251238093 0.21261694414410356 0.05723033130640079 0.04846498008021497 6.3733001029853e-08 7.195635631182469 -0.4276036859368544 T(ph)VSSPPTSPRPGSAATVSASTSNIIPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVSSPPTSPRPGSAATVSASTSNIIPPR 28 1 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 1 T(0.304)VS(0.091)S(0.304)PPT(0.102)S(0.051)PRPGS(0.003)AAT(0.008)VS(0.036)AS(0.015)T(0.043)S(0.043)NIIPPR 50.464 0.011128 61348000.0 20636.0 18288.0 20442.0 18216.0 26941.0 19209.0 21531.0 17187.0 18608.0 18602.0 True False 24129.267220421523 20103.511778818538 20929.41480671671 17195.41657706882 21662.104447586687 18201.646224488126 19491.42780905909 16735.859461131768 18880.106797122604 21974.39534664901 1.0980628517772217 0.9148607486887792 0.9524455383892212 0.7825205793292073 0.9857884190151359 0.828311584339625 0.887006331759269 0.7616072796143584 0.8591866351399621 1.0 14.42353584788093 -1.5228832616994743 0.8988228215338453 0.8660129728646906 114.11923106041812 0.4152644748342391 0.07608493631778966 799.3375070927209 1.775977487753212 0.02413089803339891 185674.9851701355 0.02999968801844088 1.5228832616994743 113.25321808755342 T(ph)VSSSGCEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVSSSGCEGK 10 0 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 T(0.777)VS(0.072)S(0.138)S(0.013)GCEGK 96.113 0.01383 6219700.0 16432.0 20387.0 24679.0 17861.0 40026.0 28242.0 23621.0 24794.0 29375.0 26467.0 True False 19213.613053206354 22410.88662701081 25267.440955628685 16860.30607614329 32183.192629045156 26760.939802800447 21383.44787876944 24143.183771414497 29804.55380295983 31265.257587343283 0.6145355751357813 0.716798400409889 0.8081635305591527 0.5392665014526742 1.0293595867277763 0.8559321709741402 0.6839364050986046 0.7722048572274701 0.9532802894617836 1.0 14.932272782883636 -3.138181288773142 0.08080694172850783 1.1922083792976785 1.3843655446439998e-13 0.3632953539990238 0.12432736029562266 170.61247483988333 1.4121719628094607 4.1610265788670695 23.708851380820725 0.0007274760687549532 3.138181288773142 -1.1922083792975402 T(ph)VSSSGCEGK ddPTM_PC-9_Lapatinib_30min_R1 2 TVSSSGCEGK 10 0 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 T(0.994)VS(0.005)S(0.001)SGCEGK;T(0.97)VS(0.03)SSGCEGK 139.32 0.00029559 16305800.0 27155.0 56888.0 43956.0 39024.0 72399.0 41466.0 78897.0 73304.0 62927.0 58514.0 True False 26767.764720382886 56756.279331188285 40342.10735506679 41893.95514024782 68140.63316191052 39692.59584196715 82981.90061401422 76709.97144940871 55839.498609313414 68628.0669349959 0.3900410708892202 0.8270126475359927 0.5878368597104534 0.6104492959116788 0.992897457339909 0.5783726340356307 1.209153984952165 1.1177638373825673 0.8136539626302494 1.0 16.066511098028535 -6.628350770902414 0.9495832295265721 1.0256567905991831 0.6004439823178737 0.450415646916274 0.1879871886364417 0.5163561442636451 1.0126090263024148 0.10320727012012047 0.10898490071981586 2.3531479259889989e-07 6.628350770902414 -0.4252128082813095 T(ph)VSVPSEGQFPEYPPEGATK ddPTM_PC-9_Lapatinib_30min_R1 1 TVSVPSEGQFPEYPPEGATK 20 0 Q9UJF2-2 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 T(0.526)VS(0.447)VPS(0.026)EGQFPEYPPEGATK 105.73 0.004048599999999999 0.0 25287.0 20856.0 28215.0 23858.0 29952.0 24204.0 24291.0 24529.0 32313.0 21336.0 True False 24926.402742932132 20807.70921338882 25895.271613049626 25612.59690795491 28190.282247897696 23168.851342279777 25548.66912322417 25668.706887517 28673.5696690251 25023.899171567027 0.9961038674282354 0.8315134692131122 1.0348216093546556 1.0235254199336281 1.126534360397696 0.9258689536523143 1.0209707507235084 1.0257676755940028 1.1458473946220558 1.0 14.611018984288918 -5.294316695859679 22.15900650850502 1.0368813485663149 0.9138087838950264 0.34057978056405047 0.06906484847150715 152.37338514043643 102698.00164559747 0.017529956979602194 0.03650078107702629 5.077890180326584e-06 5.294316695859679 -0.12307256467128846 T(ph)VTPASSAK ddPTM_PC-9_AZD4547_30min_R2 4 TVTPASSAK 9 0 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 1 T(0.998)VT(0.002)PASSAK;T(1)VTPASSAK;T(1)VTPASSAK;T(0.93)VT(0.064)PAS(0.003)S(0.004)AK 130.98 0.0030523000000000004 389414000.0 2169510.0 2025340.0 2568930.0 3327620.0 2854520.0 2749620.0 2498630.0 2564400.0 2373900.0 2647500.0 True False 2859369.0513886767 2679991.5473176427 2534864.3096909574 2560488.6202165056 2458219.170601815 2577685.8267318862 2721003.2295123166 2168130.904049659 2499379.5075871004 2554811.8308362793 1.1192092571658028 1.0489976267412178 0.9921921759933324 1.0022219990183654 0.9621918690572032 1.0089532996596933 1.0650503480021998 0.8486460246819642 0.9783027765175825 1.0 21.28478560580355 -1.5228787756118576 0.581809615319208 0.9708411441949946 9.33817909914569 0.42248871947614797 0.051390873745571664 153.9076956203548 1.2698892287996295 0.024528796451320774 1627.7833194757613 0.0299999979047729 1.5228787756118576 8.367337954950695 T(ph)VTPASSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TVTPASSAK 9 0 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 1 T(0.605)VT(0.395)PAS(0.001)SAK;T(0.997)VT(0.002)PASSAK;T(0.572)VT(0.16)PAS(0.211)S(0.057)AK;T(1)VTPASSAK 104.05 0.006673 229951000.0 1489650.0 1691880.0 1653860.0 1824680.0 1787640.0 1453940.0 1494170.0 1352260.0 1422750.0 1104560.0 True False 1741818.323071374 1859838.6651546068 1693294.2946989806 1722449.0952923754 1437364.7746811113 1377692.826884911 1352631.4007459867 1316764.6078379038 1443555.0271714425 1304807.984307853 1.3349231028773456 1.425373455344983 1.2977344674950035 1.3200785985426535 1.1015910325254288 1.0558586730412447 1.036651688994302 1.0091635119296065 1.1063352190760767 1.0 20.315406084572217 -6.274785677996534 1.8925137603004798 1.0388165983760638 1.363988329506763 0.9287180324883256 0.04009704773208728 0.07858888464144514 0.5537496522922877 0.013414003699271614 0.017431642626592584 5.311464975197636e-07 6.274785677996534 0.3251717311306992 T(ph)VTPASSAK ddPTM_PC-9_Lapatinib_30min_R1 4 TVTPASSAK 9 0 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 1 T(0.994)VT(0.006)PASSAK;T(0.943)VT(0.056)PASSAK;T(0.99)VT(0.01)PASSAK;T(1)VTPASSAK 128.27 0.0032655 399543000.0 1411980.0 1687320.0 1624770.0 1469750.0 1554720.0 1349350.0 1255690.0 1299230.0 1259630.0 933140.0 True False 1391844.9062745802 1683413.1142086294 1491187.6823935749 1577840.317942269 1463274.4262971256 1291641.4459884826 1320703.4840616419 1359596.968872305 1117757.2049080583 1094432.0056691088 1.2717509165164083 1.538161444008056 1.3625219974098797 1.4416978942219587 1.3370172095821664 1.1801934147556337 1.2067478630197737 1.2422854611612724 1.0213126070127025 1.0 20.061750895582527 -7.443875656416983 0.5367494091804735 1.0000638795173462 1.4343118248260167 0.7409558606502273 0.08223482800280611 0.43131292125946036 0.26461376518645924 0.07774383861478973 0.05797885348477415 3.598523503390299e-08 7.443875656416983 0.4342479453086705 T(ph)VVLTPTYSGEADALLPSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVVLTPTYSGEADALLPSLR 20 0 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 1 T(0.727)VVLT(0.27)PT(0.003)YSGEADALLPSLR 146.88 0.00043854 2680400.0 8098.5 11130.0 10844.0 11998.0 14094.0 12747.0 13704.0 11569.0 11813.0 10746.0 True False 9469.41609733397 12234.912844392524 11102.562086099015 11325.790958040825 11332.381874625551 12078.524880188988 12405.857911631869 11265.326008368738 11985.742776999647 12694.16473471081 0.7459660635599665 0.9638218110513005 0.874619348190769 0.8922045045682828 0.892723712938622 0.9515021376051296 0.9772882399823757 0.8874412963591792 0.9441931019081499 1.0 13.631877849545916 -4.753992824623595 24.999400455513964 0.9258488050582621 0.7459657458689165 0.6448306845135157 0.04112150944221025 172.43590745442432 578849.563585418 0.010121174596783395 0.10318293360671707 1.76200515787014e-05 4.753992824623595 -0.17988305918934555 T(ph)VVLTPTYSGEADALLPSLR ddPTM_PC-9_Lapatinib_30min_R1 1 TVVLTPTYSGEADALLPSLR 20 0 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 1 T(0.953)VVLT(0.041)PT(0.006)YS(0.001)GEADALLPSLR 166.36 1.0449999999999999e-07 2468900.0 8510.8 9487.4 9817.9 6029.7 10833.0 10771.0 9973.0 8351.2 10852.0 5993.6 True False 8389.434431310427 9465.43250820412 9010.710160189972 6473.14425248955 10195.824238497453 10310.349438427334 10489.35314173623 8739.22723955449 9629.733483373891 7029.585774030006 1.1934464847565023 1.3465135517903584 1.2818266182168232 0.9208429145859255 1.4504160794459255 1.466707964005181 1.492172295626285 1.2432065729734114 1.3698863336940608 1.0 12.779223964093676 -4.743277314501458 23.127331761664788 1.299059030456763 1.1934456592516673 0.017970339180436112 0.18206495859522934 2159.9861645908404 2750110.9780508084 0.046106022607718615 1.287888635798042 1.8060205409604053e-05 4.743277314501458 -0.10561337120509573 T(ph)WTLCGTPEYLAPEIILSK ddPTM_PC-9_Lapatinib_30min_R1 1 TWTLCGTPEYLAPEIILSK 19 0 B1APG2;Q15136;B1APF8;B1APF9;K7ERP6;B1APG3;A0A087WVC4;A0A0A0MS54;P22694;P22694-9;P22694-6;P22694-7;P22694-5;P22694-3;P22612;P17612;P17612-2;P22694-4;P22694-10;P22694-8;P22694-2 B1APG2 PRKACB;KIN27;PRKACA;PRKACG cAMP-dependent protein kinase catalytic subunit beta;cAMP-dependent protein kinase catalytic subunit gamma;cAMP-dependent protein kinase catalytic subunit alpha 1 T(0.523)WT(0.459)LCGT(0.018)PEYLAPEIILSK 67.413 0.019244999999999998 11433000.0 12598.0 14528.0 14100.0 8283.3 11169.0 11583.0 12677.0 11099.0 12588.0 8465.0 True False 12418.350209809749 14494.36130859765 12940.752427573985 8892.48151427877 10512.061379098866 11087.622091291785 13333.353030962613 11614.700058891563 11170.206882483466 9928.163971096501 1.2508204181521212 1.459923642558136 1.3034386282547228 0.8956823779469321 1.0588122244658977 1.1167847472675483 1.3429827579177291 1.1698739155301034 1.1251029812765865 1.0 13.277311227520997 -5.5431682278356496 24.923420409120425 1.1159726983282083 1.361949358338057 0.45414397728035194 0.1190446736986248 204.56513778162446 251284.9413607946 0.03416903248964172 0.059190389256319045 2.8630687199126715e-06 5.5431682278356496 0.24597666000984875 T(ph)WVVSPAEK ddPTM_PC-9_Lapatinib_30min_R1 1 TWVVSPAEK 9 0 P42566;B1AUU8 P42566 EPS15 Epidermal growth factor receptor substrate 15 1 T(0.931)WVVS(0.069)PAEK 101.97 0.0081327 3329000.0 42637.0 45840.0 42520.0 37392.0 46879.0 45001.0 45758.0 41768.0 45189.0 42221.0 True False 42028.98856133181 45733.86029640121 39024.169731946495 40141.93241605538 44121.6693876601 43076.41213245462 48127.12534438648 43708.69376158059 40099.33895873413 49518.843594053826 0.8487473759661587 0.9235647882111061 0.7880670649714542 0.8106395364385203 0.8910076687040847 0.8698993959872519 0.9718951787106259 0.88266790153454 0.8097793899926455 1.0 15.595690003459383 -6.567403910081182 2.667165722294832 0.9042877376173665 0.8453041724355599 0.2016010508009718 0.059365571380459115 0.5240993663154396 7.568349117070611 0.021307100080495616 0.022146921485357178 2.707672224249928e-07 6.567403910081182 -0.058983565181806585 T(ph)Y(ph)HMYHAESISAESKLKEAEKQEEK ddPTM_PC-9_AZD4547_30min_R2 1 TYHMYHAESISAESKLKEAEKQEEK 25 3 G5EA48;Q7Z6B7-2;Q7Z6B7;A0A087WZH4;O43295-3;O43295-2;O43295 G5EA48 SRGAP1;SRGAP3 SLIT-ROBO Rho GTPase-activating protein 1;SLIT-ROBO Rho GTPase-activating protein 3 2 T(0.879)Y(0.873)HMY(0.199)HAES(0.043)IS(0.003)AES(0.003)KLKEAEKQEEK 43.497 0.044538 8727500.0 24559.0 14547.0 26415.0 40783.0 31863.0 25158.0 13187.0 27019.0 16062.0 25183.0 True False 32368.251141066186 19249.03326791043 26064.719840745624 31381.109441068915 27439.372445414887 23584.866282948446 14360.617453395995 22843.83438485326 16911.00452877711 24301.35083510865 1.331952752778793 0.7920972541205802 1.0725625919975361 1.2913318956628532 1.1291295134825459 0.9705166779813291 0.5909390614059579 0.9400232332702392 0.6958874279673969 1.0 14.568748890456485 -7.006176917757144 5.604445233070874 0.7978111540619047 1.1073306003175005 0.4242889976524198 0.17320075692954265 0.16560871674455788 18.298327989582756 0.06341726687247039 0.05240450519852383 9.858777885668911e-08 7.006176917757144 0.3095194462555958 T(ph)Y(ph)VPALEQS(ph)ADGHK ddPTM_PC-9_AZD4547_30min_R2 1 TYVPALEQSADGHK 14 0 P98175-5;P98175-2;P98175;P98175-4;P98175-3 P98175-5 RBM10 RNA-binding protein 10 3 T(1)Y(1)VPALEQS(1)ADGHK 49.924 0.033214 2689600.0 32412.0 27091.0 38757.0 52423.0 49581.0 42898.0 32453.0 44977.0 37266.0 40410.0 True False 42718.34178851895 35847.63595662069 38243.05685662607 40337.68727727621 42697.53398035701 40215.581278556434 35341.25413020855 38026.83811864043 39235.80467995312 38995.25819984673 1.0954752900876255 0.9192819232765482 0.9807104407575479 1.0344254440001313 1.0949416916676509 1.0312941402376585 0.9062961950165382 0.9751656963971557 1.0061686084721793 1.0 15.251011083332587 -7.151998395641153 21.16600454971168 0.9696542827003092 1.0226267844727963 0.1904712319978854 0.05430208226142476 15.234602725486667 2923.316921505816 0.021797053688867158 0.01688391403535323 7.04695672229899e-08 7.151998395641153 0.052972501772487135 T(ph)YSAPAINAIQVPKPFSGPVR ddPTM_PC-9_Lapatinib_30min_R1 1 TYSAPAINAIQVPKPFSGPVR 21 1 Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 T(0.482)Y(0.035)S(0.482)APAINAIQVPKPFSGPVR 97.78399999999999 0.00020078 44218000.0 32945.0 19680.0 22148.0 17127.0 17050.0 19163.0 15455.0 10645.0 22140.0 11760.0 True False 32475.19825862694 19634.432169135587 20327.076933752367 18386.57671399713 16047.152521589724 18343.44316113483 16255.18427810423 11139.605561483082 19646.36005546423 13792.700330784986 2.3545206870146416 1.423537936607815 1.4737561497209364 1.3330657719691565 1.163452560900845 1.329938497988874 1.178535304056671 0.8076450074551204 1.4244027336412153 1.0 13.75161731446172 -1.525748931256588 0.7490049596939675 1.1568036579790308 199.9999999278852 0.786366301075551 0.18001377677817912 162.01970936366803 0.7058465898925778 0.06536899926615064 54345.797144964825 0.029802388288789602 1.525748931256588 198.84319626990617 up T(ph)YSDEANQMR ddPTM_PC-9_AZD4547_30min_R2 1 TYSDEANQMR 10 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 T(0.987)YS(0.013)DEANQMR 122.18 0.0013705 33014000.0 13224.0 15529.0 15717.0 29437.0 18938.0 13951.0 17079.0 21259.0 15839.0 16773.0 True False 17428.956923712663 20548.44556385379 15508.582310694637 22650.75444711635 16308.785593675013 13078.641764584389 18598.997913592953 17973.910033220916 16676.21720404063 16185.782375303874 1.076806577500116 1.2695367506736301 0.9581608074971709 1.3994228960891426 1.0075994607810133 0.8080327204040298 1.1490947723337206 1.1104752069720987 1.0303003473891417 1.0 13.982439482612184 T(ph)YSDEANQMR ddPTM_PC-9_Lapatinib_30min_R1 2 TYSDEANQMR 10 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 T(0.96)YS(0.04)DEANQMR;T(0.928)YS(0.072)DEANQMR 124.39 0.0010134 69472000.0 45832.0 38620.0 54012.0 38676.0 47544.0 40850.0 38843.0 38023.0 39105.0 38216.0 True False 45178.42727544057 38530.57776280572 49571.341852349324 41520.362059353814 44747.555395100404 39102.94072600101 40854.10047974131 39789.687389785926 34700.583106094346 44821.58468038087 1.0079614006868414 0.8596433624014899 1.1059703088554007 0.9263474809164423 0.9983483563598128 0.8724131688971051 0.911482732506417 0.887734953449839 0.7741935800249239 1.0 15.451906036209259 -6.765237625963247 24.985357825148935 0.8835431746808194 0.9770429975068162 0.25002949546082487 0.07799129861401595 135.18245299886817 889241.4954026581 0.025764903841414326 0.023584038842744317 1.7169686838154155e-07 6.765237625963247 0.09349982282599678 T(ph)YSFEQPWPNAR ddPTM_PC-9_AZD4547_30min_R2 1 TYSFEQPWPNAR 12 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-5 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 T(0.583)YS(0.417)FEQPWPNAR 104.59 0.004626 39824000.0 16710.0 11786.0 24815.0 22445.0 22526.0 25965.0 16551.0 24748.0 13444.0 21758.0 True False 22023.432410408226 15595.594012208176 24485.936886167052 17270.6520217932 19398.65372706322 24341.404445375498 18024.006936464477 20923.765252464884 14154.622393530033 20996.259042619775 1.0489217324716473 0.7427796532968599 1.166204743257533 0.8225585322954885 0.9239100016667915 1.1593210198047899 0.8584389676217083 0.9965472996876378 0.6741497313782385 1.0 14.357844681658174 T(ph)YSFEQPWPNAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TYSFEQPWPNAR 12 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-5 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 T(0.756)YS(0.244)FEQPWPNAR;T(0.987)YS(0.013)FEQPWPNAR 146.67 0.00030812 28390200.0 36080.0 33323.0 40620.0 44425.0 57194.0 50448.0 56882.0 46217.0 46909.0 41969.0 True False 42187.63138751738 36631.08721596515 41588.53485220788 41936.01127779329 45987.24627056435 47802.41807137163 51493.72516998277 45003.85272095929 47594.955381890846 49577.64747357882 0.8509405657055477 0.7388629570510941 0.8388565607993291 0.8458652924211874 0.9275802425896088 0.9641929479781537 1.0386480156692606 0.9077448207872908 0.960008346649675 1.0 15.597402194767458 -6.220864171574952 1.582135135313421 0.9731340352547676 0.7992116124229197 0.7656901955921542 0.04115275206796965 0.18068529247935416 0.899418102330425 0.014859625086810272 0.020853246025318066 6.013617878868059e-07 6.220864171574952 -0.1739224228318479 T(ph)YSQDCSFK ddPTM_PC-9_AZD4547_30min_R2 1 TYSQDCSFK 9 0 Q86U86-8;Q86U86;E7EVG2;Q86U86-5;Q86U86-4;Q86U86-7;Q86U86-9;Q86U86-2;Q86U86-3;H0Y5B5 Q86U86-8 PBRM1 Protein polybromo-1 1 T(0.599)YS(0.401)QDCSFK 127.87 0.0032971 6662800.0 13926.0 20357.0 19629.0 28055.0 27857.0 21555.0 14402.0 22042.0 19802.0 19794.0 True False 18354.178321205567 26937.002147167976 19368.706634639235 21587.353195429176 23989.536396821477 20207.16244252143 15683.750099629118 18635.915374770924 20848.69329341576 19101.018084824704 0.9609005258095388 1.4102390787519734 1.0140143603145009 1.1301676748099518 1.2559297253312682 1.0579102303753918 0.8210949819522697 0.9756503706771896 1.0914964427984883 1.0 14.221361915547853 -6.998332844313297 24.121226246155626 0.965670064375187 1.1591007976183125 0.30039570363749535 0.13100733112388907 40.48766458496734 585775.3839536457 0.04467648161002658 0.039091510334928144 1.0038461453382934e-07 6.998332844313297 0.19343073324312554 T(ph)YSQDCSFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TYSQDCSFK 9 0 Q86U86-8;Q86U86;E7EVG2;Q86U86-5;Q86U86-4;Q86U86-7;Q86U86-9;Q86U86-2;Q86U86-3;H0Y5B5 Q86U86-8 PBRM1 Protein polybromo-1 1 T(0.984)YS(0.016)QDCSFK 93.561 0.015065 3542200.0 8903.3 11379.0 3272.4 14216.0 10080.0 11757.0 12713.0 9510.9 7795.3 9063.5 True False 10410.452841809409 12508.631918808856 3350.4264266461078 13419.523608893847 8104.896359885453 11140.442222984373 11508.73260585055 9261.248952631531 7909.291515241292 10706.640803373475 0.9723360513345378 1.168305927930972 0.3129297496924009 1.2533831904275325 0.7569971299804643 1.0405170424204588 1.0749153555449762 0.8650004350303294 0.738727642076982 1.0 13.386218286668898 T(ph)YSSSGSSGGSHPSSR ddPTM_PC-9_AZD4547_30min_R2 1 TYSSSGSSGGSHPSSR 16 0 H0Y6B5;B7Z836;E7EW77;E7EP65;A0A0C4DG21;F8WAL6;Q9NYB9-3;Q9NYB9-2;Q9NYB9-4;Q9NYB9 H0Y6B5 ABI2 Abl interactor 2 1 T(0.853)YS(0.146)SSGSSGGSHPSSR 170.42 7.086399999999999e-05 1727000.0 0.0 0.0 3374.5 8116.9 4572.6 2417.8 765.81 4578.1 2099.5 3263.5 True False 0.0 0.0 3329.751925140867 6245.674109854895 3937.77341882133 2266.6145837869776 833.9656064294525 3870.6598392722412 2210.4752837858 3149.245858332091 0.0 0.0 1.0573172355950564 1.9832284905068478 1.250386154641753 0.7197324965245572 0.26481438539420316 1.2290751543044742 0.7019062287364619 1.0 11.620790676225798 -5.260797032578427 24.999999998789214 1.0380934881580262 3.430535999135443e-05 0.48465512365270913 0.4229632597224939 49.762245026875895 1936632.6393253936 0.12085045216233825 0.283292900855198 5.485332619139306e-06 5.260797032578427 -1.0380591827980348 T(ph)YSSSGSSGGSHPSSR ddPTM_PC-9_Lapatinib_30min_R1 1 TYSSSGSSGGSHPSSR 16 0 H0Y6B5;B7Z836;E7EW77;E7EP65;A0A0C4DG21;F8WAL6;Q9NYB9-3;Q9NYB9-2;Q9NYB9-4;Q9NYB9 H0Y6B5 ABI2 Abl interactor 2 1 T(0.789)YS(0.07)S(0.07)S(0.07)GSSGGSHPSSR 104.84 0.0025138 556800.0 2288.9 2457.7 2655.0 929.45 2147.4 2549.2 1170.8 2125.2 1274.8 931.77 True False 2256.2598662671485 2452.0093466506382 2436.7161485963775 997.8048535543079 2021.0941539508378 2440.1766584754405 1231.4182952316025 2223.944550424035 1131.2185997608772 1092.8252029945181 2.06461185200033 2.2437342586277618 2.229740073636095 0.9130507338412044 1.8494212509125085 2.2329066458102917 1.1268209150533104 2.0350414177217604 1.0351322395028546 1.0 10.093846945562253 -1.522878745664378 0.0736092159872679 0.23514977812187937 5.2768680028515895 0.3432627864883362 0.4438994811976349 277.5648734543926 1.5077746750369418 17.123362963697637 143.87117803490597 0.029999999973471428 1.522878745664378 5.04171822472971 T(ph)YTHEVVTLWYR ddPTM_PC-9_AZD4547_30min_R2 2 TYTHEVVTLWYR 12 0 G3V5T9;P24941;Q00526;K7EJ83 G3V5T9 CDK2;CDK3 Cyclin-dependent kinase 2;Cyclin-dependent kinase 3 1 T(0.787)Y(0.014)T(0.199)HEVVTLWYR;T(0.886)Y(0.016)T(0.099)HEVVTLWYR 78.985 0.033296 15020800.0 28189.0 28872.0 35255.0 44356.0 42398.0 39512.0 40208.0 45103.0 42526.0 39435.0 True False 37152.515632375675 38204.309377267455 34787.49566479224 34130.409493368614 36511.7695427518 37041.3083938254 43786.434106782894 38133.36771383238 44773.837541450324 38054.392653079805 0.9763003175763169 1.003939537954379 0.9141519083468234 0.8968848827654692 0.9594626795284522 0.9733779942701984 1.150627589985704 1.0020753204885582 1.1765747505058841 1.0 15.215775374488329 -7.11400954774213 5.848076381799021 1.0819756828916745 0.9498577809809423 0.5351992910131268 0.05885250844253215 0.1798880760149926 8.06049726591401 0.02183337638560926 0.01688781712571078 7.691135315330017e-08 7.11400954774213 -0.13211790191073214 TAAAAAEHSQR ddPTM_PC-9_AZD4547_30min_R2 3 TAAAAAEHSQR 11 0 O43242 O43242 PSMD3 26S proteasome non-ATPase regulatory subunit 3 0 ;; 126.71 0.00033323 4387100.0 33828.0 25467.9 30683.5 41976.0 39257.0 36230.6 29811.6 28807.5 37613.0 45432.0 False True 44584.600333889255 33699.90062307117 30276.616741757265 32299.081722735187 33806.84317514522 33965.09485455889 32464.7746472784 24355.96280549467 39601.14639153862 43841.43950842456 1.0169511045667623 0.7686768728612435 0.6905935818083555 0.7367249361538095 0.7711161757963925 0.7747258127332285 0.7405043039483221 0.5555466033640257 0.9032811612841515 1.0 15.420007548686627 -4.763706442629237 5.373012332342404 0.7519584097288419 1.030339777278441 0.2859147107831629 0.11314781168982434 0.17178886337010388 15.015566581179513 0.026146656965333935 0.17846340497673022 1.723032849698676e-05 4.763706442629237 0.2783813675495992 TAAAAAEHSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TAAAAAEHSQR 11 0 O43242 O43242 PSMD3 26S proteasome non-ATPase regulatory subunit 3 0 ; 110.31 0.001639 3625500.0 22416.3 29205.0 29535.0 29868.0 37948.0 35052.0 25642.0 28372.0 33977.0 31619.0 False True 26210.93684789374 32104.27939087902 30239.226412111253 28194.592793362503 30512.361811997318 33213.81141448061 23213.004127996526 27627.265062618855 34473.8493468312 37351.2744041337 0.7017414336200789 0.85952299896161 0.8095902186610439 0.754849553145158 0.8169028312624451 0.8892283314114928 0.6214782359722516 0.7396605739257271 0.9229631357107309 1.0 15.188869847333917 -8.43702743284003 3.9614282696580694 0.9976730427909417 0.7782295962920163 0.519370282939122 0.07365119556792758 0.17102526468734086 4.7455741847360144 0.07242948678948917 0.019037599482814006 3.6557169901789133e-09 8.43702743284003 -0.21944344649892544 TAAAAAEHSQR ddPTM_PC-9_Lapatinib_30min_R1 1 TAAAAAEHSQR 11 0 O43242 O43242 PSMD3 26S proteasome non-ATPase regulatory subunit 3 0 81.709 0.012384000000000001 1661400.0 8494.5 9789.9 10338.0 7412.9 9148.7 8905.9 10775.0 11210.0 11289.0 7896.5 False True 8373.366872299479 9767.232088039664 9488.049545834027 7958.0693947094815 8610.591453036248 8525.015417666886 11332.876777520087 11730.857524116991 10017.513941559888 9261.399503575138 0.9041146393768182 1.0546172945319183 1.0244725478229717 0.8592728768084632 0.9297289734356389 0.9204888974259248 1.2236678455718604 1.266639833384639 1.0816414881674061 1.0 13.177014502370985 -7.25703431277161 24.97625710293825 1.1652072810688554 0.9520989666610823 0.5374382776961115 0.0872637571185238 270.6484567894744 1534552.4163943722 0.03448433564614096 0.02577546645968934 5.5330639181506324e-08 7.25703431277161 -0.21310831440777311 TAAALAPAS(ph)LTSAR ddPTM_PC-9_AZD4547_30min_R2 2 TAAALAPASLTSAR 14 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 TAAALAPAS(0.888)LT(0.102)S(0.01)AR;TAAALAPAS(0.9)LT(0.077)S(0.023)AR 102.63 0.0014138 14631100.0 48208.0 52494.0 71388.0 97808.0 87535.0 84101.0 74080.0 90256.0 67070.0 76571.0 True False 63537.14121130818 69461.65892388044 70441.34847590936 75259.87671853646 75382.27621408502 78842.15117506332 80672.97648802405 76309.00907655046 70615.1832738812 73890.27259639848 0.8598850562963692 0.9400649975036918 0.9533237055528574 1.0185356485233041 1.0201921520284019 1.0670166505639092 1.0917942734989472 1.0327341664221965 0.9556763128970115 1.0 16.173096830515746 -5.146126323188633 0.9974261785702926 1.0354459205258193 0.8340972873321617 0.6804037171472239 0.036523247905406814 0.6999250530363643 0.8281802331136774 0.013451995578721529 0.13307965097112734 7.142885308291506e-06 5.146126323188633 -0.2013486331936576 TAAALAPAS(ph)LTSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TAAALAPASLTSAR 14 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 TAAALAPAS(0.993)LT(0.003)S(0.003)AR;TAAALAPAS(0.555)LT(0.207)S(0.237)AR 86.214 0.006589399999999999 9101100.0 67592.0 61746.0 52265.0 59218.0 56667.0 45323.0 47161.0 43787.0 45862.0 34358.0 True False 79033.9905971472 67875.73481490213 53511.19581611628 55900.207447346394 45563.5081374632 42946.18209341846 42693.568663928054 42637.637646161456 46532.644987620195 40586.83342222166 1.9472815179977894 1.6723584742075381 1.3184373183156095 1.37729905819015 1.1226179599543917 1.0581308880801978 1.0519068639770488 1.0505288057978173 1.1464960693913893 1.0 15.308724165156233 -4.216672162628721 0.5436912536443642 1.0398898508306895 3.292508165485537 0.957407537556751 0.061387183569478795 1.2983209309524693 0.18601599519271372 0.03342577404679253 2.112750139907191 6.071945116442177e-05 4.216672162628721 2.2526183146548475 TAAALAPAS(ph)LTSAR ddPTM_PC-9_Lapatinib_30min_R1 2 TAAALAPASLTSAR 14 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(0.001)AAALAPAS(0.966)LT(0.028)S(0.005)AR;TAAALAPAS(0.87)LT(0.122)S(0.008)AR 125.33 3.5338e-05 15071600.0 107395.0 98327.0 108276.0 91276.0 78788.0 81355.0 79348.0 66826.0 77217.0 54821.0 True False 105863.5276061688 98099.3298726931 99373.96523744683 97988.74152781004 74153.8447431678 77875.63629776773 83456.2511872543 69930.97992030691 68520.00832894223 64296.736805609136 1.6464836765546935 1.5257279723118868 1.545552234445242 1.5240080040774584 1.1533065039888424 1.2111911143051042 1.297985797313025 1.0876287568330567 1.065684072523019 1.0 15.972457899158218 -6.141494673074167 0.4178118655389837 1.00966378797295 1.7676474492833574 0.8724454208584217 0.07990568845991941 0.6809497600993599 0.20184257656306556 0.0799411724227838 0.23087734374074992 7.219470180684023e-07 6.141494673074167 0.7579836613104074 TAADVVS(ph)PGANSVDSR ddPTM_PC-9_AZD4547_30min_R2 2 TAADVVSPGANSVDSR 16 0 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 T(0.087)AADVVS(0.902)PGANS(0.01)VDSR;TAADVVS(0.999)PGANS(0.001)VDSR 219.85 2.1706e-22 104685000.0 68683.0 58818.0 77921.0 112725.0 94076.0 82965.0 63439.0 98553.0 65469.0 68166.0 True False 90522.76530485162 77829.76825132035 76887.71662732303 86737.99283388907 81015.17126996355 77777.1854346456 69084.94810237255 83323.89837264307 68929.5576823875 65779.52908811568 1.3761540491357254 1.1831913260896507 1.168869976620344 1.3186168103711757 1.2316167718598108 1.1823919464436774 1.0502499646938648 1.2667147291526766 1.0478876732311684 1.0 16.0053510595885 -6.9157196535423076 0.03030860626694836 9.65756216587927e-07 2.3716660927599347 0.5273234164570505 0.07977461169105841 198.80150157562235 2.6671663896381688 96.44638614499571 111.25227721321143 1.2141723720088585e-07 6.9157196535423076 2.371665127003718 TAADVVS(ph)PGANSVDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TAADVVSPGANSVDSR 16 0 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 TAADVVS(0.987)PGANS(0.01)VDS(0.003)R;TAADVVS(0.894)PGANS(0.068)VDS(0.038)R;TAADVVS(0.994)PGANS(0.006)VDSR 176.44 9.9277e-06 68424700.0 113462.0 103304.0 105145.0 97280.0 120517.0 91255.0 96604.0 91262.0 88506.0 77703.0 True False 132668.8756233509 113559.33840764813 107652.0555646329 91829.71698601513 96902.55898852336 86469.4271547538 87452.96976760689 88866.46920008199 89800.2328130985 91789.93880339028 1.4453531329563405 1.2371654223551327 1.1728088826294842 1.0004333610321938 1.0556991349137304 0.9420360039673545 0.952751150155215 0.9681504352065184 0.9783232670570394 1.0 16.48604840645715 -4.557719323827486 0.6811918966117756 0.9639207480696192 1.8792451411185274 0.9505810647979346 0.03429318556024584 0.7579827211618415 0.2154674623711613 0.014255382636245366 0.5753329339648476 2.768730444561821e-05 4.557719323827486 0.9153243930489081 TAADVVS(ph)PGANSVDSR ddPTM_PC-9_Lapatinib_30min_R1 2 TAADVVSPGANSVDSR 16 0 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 TAADVVS(0.993)PGANS(0.007)VDSR;TAADVVS(0.995)PGANS(0.004)VDS(0.001)R 154.47 1.7453e-05 52049800.0 128870.0 117419.0 125457.0 113252.0 118801.0 113093.0 106859.0 97850.0 130174.0 98351.0 True False 127032.29016813607 117147.12351970158 115142.40973802475 121580.92987759721 111813.35875175252 108256.2760226592 112391.6361548975 102396.46821898741 115512.43332701009 115350.83930552982 1.1012688848467378 1.0155723549562907 0.9981930814828924 1.0540099284025646 0.9693328581302509 0.9384957809966233 0.9743460631197118 0.8876959095873576 1.0014008915969155 1.0 16.815668975705393 -6.356742765086136 4.714271123055774 0.9543328479622473 1.03708706522532 0.48976985005791585 0.03980765403226334 0.1897648892333268 7.030267147549315 0.012189019004996185 0.013925077205706763 4.3980203537301296e-07 6.356742765086136 0.08275421726307264 TAADVVSPGANS(ph)VDSR ddPTM_PC-9_Lapatinib_30min_R1 1 TAADVVSPGANSVDSR 16 0 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 TAADVVS(0.334)PGANS(0.629)VDS(0.038)R 84.40299999999999 0.0049805 7098200.0 25054.0 24287.0 24759.0 25999.0 23822.0 25567.0 23408.0 26408.0 23490.0 25656.0 True False 24696.725365659087 24230.764943688835 22723.410592503828 27911.053190121514 22420.836795854 24473.559009587945 24619.95170377636 27635.012087143747 20844.308839334008 30090.60541552889 0.8207453796497501 0.8052601338218353 0.7551662812598956 0.9275670198286349 0.7451108572339743 0.8133289002207263 0.8181939633248694 0.9183933558505977 0.692718160751158 1.0 14.87702551317964 -10.795075805209319 4.126067561998321 1.0001823276215953 0.8138962549172446 0.40700873652359926 0.06844395039466009 11765461.86577332 30782161.239552286 11125.92670725788 0.01545066278991963 1.6029655719234547e-11 10.795075805209319 -0.1862860727043507 TAAELLQSQGSQAGGS(ph)QTLK ddPTM_PC-9_Lapatinib_30min_R1 1 TAAELLQSQGSQAGGSQTLK 20 0 B1AMS2;Q14141-2;Q14141-4;Q14141 B1AMS2 SEPT6 Septin-6 1 TAAELLQSQGSQAGGS(0.5)QT(0.5)LK 122.19 0.00017536 0.0 7328.5 7493.8 6410.7 7562.6 7864.1 7830.9 7277.7 5480.6 5129.3 5069.7 True False 7223.994246117696 7476.448566517703 5883.636992017626 8118.778832094045 7401.549099415476 7495.99066171949 7654.5036959404115 5735.248683913969 4551.584220076458 5945.990890049375 1.2149353034171415 1.2573932090998576 0.9895132873250616 1.3654206644818165 1.2447965757569492 1.2606798093592848 1.287338618151978 0.964557260508407 0.7654879235845352 1.0 12.537701537532492 -7.871119892564879 4.660417336332513 0.8782435673420044 1.2294656256560086 0.66569425237144 0.10511368924648112 0.12093035848250056 4.34692273394366 0.05972280048121402 0.027561784502297095 1.345488863314007e-08 7.871119892564879 0.3512220583140042 TAAELLQSQGSQAGGSQT(ph)LKR ddPTM_PC-9_AZD4547_30min_R2 2 TAAELLQSQGSQAGGSQTLKR 21 1 B1AMS2;Q14141-2;Q14141-4;Q14141 B1AMS2 SEPT6 Septin-6 1 TAAELLQSQGSQAGGS(0.021)QT(0.979)LKR;TAAELLQSQGS(0.002)QAGGS(0.192)QT(0.806)LKR 104.89 7.5823e-05 20272400.0 31014.0 26121.0 38851.0 51246.0 43717.0 56720.0 44039.0 32082.0 35499.0 35917.0 True False 40875.80686872537 34564.10242600457 38335.81035520757 39432.0264428075 37647.64916034906 53173.2894335335 47958.38568515251 27124.464071018996 37375.40466735515 34659.556762283966 1.1793516907638542 0.997245944691847 1.1060675304689427 1.1376956350958554 1.0862126546672026 1.5341595334939746 1.383698759164172 0.7825969690568995 1.0783578371673388 1.0 15.080965584510786 -7.764362044621992 24.999998433115163 0.9478580875230287 1.1974875545808787 0.33472590331932384 0.16119039554789139 99.73586649221915 853090.9087242406 0.09129549921137495 0.046871602822599244 1.7204337571074015e-08 7.764362044621992 0.24962946705785005 TAAELLQSQGSQAGGSQT(ph)LKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TAAELLQSQGSQAGGSQTLKR 21 1 B1AMS2;Q14141-2;Q14141-4;Q14141 B1AMS2 SEPT6 Septin-6 1 TAAELLQSQGSQAGGS(0.028)QT(0.972)LKR;TAAELLQSQGSQAGGS(0.11)QT(0.89)LKR 116.05 2.7536e-06 5763600.0 23770.0 21545.2 27811.0 30274.0 29208.0 24520.0 22891.0 20325.9 18435.0 19687.1 True False 27793.791521099993 23684.06506873368 28474.119713804852 28577.845929632265 23484.902071382374 23234.12803500696 20722.598763511738 19792.366662071225 18704.576999406447 23256.215387002147 1.1951124058058857 1.0183972187482688 1.2243660131269245 1.2288261634179896 1.0098333576884586 0.9990502602582736 0.8910563657358264 0.8510570758272706 0.804282927731242 1.0 14.505328717691144 -6.776719616890255 1.5711009924319337 0.8744233409218296 1.1573295324365394 0.7099493766241574 0.07779152259955342 0.20618342501288983 1.0566054894190116 0.034742254521945085 0.03116810252559958 1.6721698287219024e-07 6.776719616890255 0.28290619151470975 TAAELLQSQGSQAGGSQT(ph)LKR ddPTM_PC-9_Lapatinib_30min_R1 2 TAAELLQSQGSQAGGSQTLKR 21 1 B1AMS2;Q14141-2;Q14141-4;Q14141 B1AMS2 SEPT6 Septin-6 1 TAAELLQSQGS(0.001)QAGGS(0.062)QT(0.937)LKR;TAAELLQS(0.003)QGS(0.002)QAGGS(0.149)QT(0.845)LKR 73.21300000000001 0.0015789999999999999 13137500.0 45917.0 31396.0 32982.0 33705.0 33611.0 29199.0 24846.0 24450.0 28637.0 19688.4 True False 45262.21515985346 31323.30449096449 30270.347274201773 36183.77813658395 31634.06706176849 27950.22683619347 26132.404307588335 25586.036259113323 25411.59949902121 23091.513706856047 1.9601233481031937 1.3564855422043796 1.3108862267965689 1.5669729839252897 1.3699434113916964 1.2104112008861 1.131688664473712 1.108027675618192 1.1004735255392248 1.0 14.495075128053234 -1.5228787452803938 0.22922022651972285 0.9929341106536005 5.3437892478688 0.7499279401000292 0.13389749077074947 27.64550157350615 0.3612274196316011 0.20632835738622538 45.07791677335612 0.029999999999996117 1.5228787452803938 4.3508551372152 TAAENVCY(ph)T(ph)LINVPMDS(ph)EPPS(ph)EISLK ddPTM_PC-9_Lapatinib_30min_R1 1 TAAENVCYTLINVPMDSEPPSEISLK 26 0 E9PP73;P53618;E9PP63;E9PKQ1 E9PP73 COPB1 Coatomer subunit beta 4 T(0.018)AAENVCY(0.99)T(0.991)LINVPMDS(0.863)EPPS(0.569)EIS(0.569)LK 42.38399999999999 0.036832 4548200.0 18733.0 35001.0 22933.0 26210.0 30548.0 31391.0 39571.0 36575.0 26735.0 31046.0 True False 18465.863984788528 34919.95733495502 21047.53726394001 28137.570833996906 28751.226699678788 30048.48010599505 41619.79275760996 38274.40802360206 23723.82276796914 36412.25973380531 0.5071331502022857 0.9590164848389009 0.5780343603448312 0.7727499210348062 0.789602922473554 0.825229752991625 1.1430159254568306 1.051140695562707 0.6515339322910474 1.0 15.152136656327261 -6.8992727245106265 2.8134496296676006 0.9666711277743916 0.725702184254291 0.31517756937616104 0.16486305677283075 0.3308452596686278 5.293136648662126 0.06243300957524086 0.05355141505753907 1.2610353917440286e-07 6.8992727245106265 -0.24096894352010056 TAAILHGGS(ph)PDFVGNGK ddPTM_PC-9_AZD4547_30min_R2 2 TAAILHGGSPDFVGNGK 17 0 H0YME5;Q9P2K8-2;Q9P2K8;Q9P2K8-3 H0YME5 EIF2AK4 Eukaryotic translation initiation factor 2-alpha kinase 4 1 T(0.001)AAILHGGS(0.999)PDFVGNGK;TAAILHGGS(1)PDFVGNGK 103.73 0.00047387 18698600.0 131219.0 102266.0 131455.0 172584.0 141180.0 126283.0 123841.0 161031.0 123329.0 141648.0 True False 172943.9124752463 135321.4845793721 129711.82080882874 132797.4251962199 121579.59394418805 118386.50404680733 134862.60908819424 136147.3590742557 129847.91915885649 136688.9466342958 1.265236997823597 0.9899958110103645 0.9489561811890027 0.9715300941744217 0.8894617812036254 0.8661015170710495 0.9866387327500018 0.9960378101274782 0.9499518604548023 1.0 17.06053705841493 -4.749044357574652 3.3382072648958907 0.9483122767305678 1.3214140025355703 0.8358489085177015 0.04148866304239463 0.14746742333504786 2.4401973755706914 0.011384623112764553 0.14894654844995942 1.7821967297637853e-05 4.749044357574652 0.37310172580500245 TAAILHGGS(ph)PDFVGNGK ddPTM_PC-9_Lapatinib_30min_R1 2 TAAILHGGSPDFVGNGK 17 0 H0YME5;Q9P2K8-2;Q9P2K8;Q9P2K8-3 H0YME5 EIF2AK4 Eukaryotic translation initiation factor 2-alpha kinase 4 1 TAAILHGGS(1)PDFVGNGK;T(0.001)AAILHGGS(0.999)PDFVGNGK 83.167 0.0022581 13975200.0 146871.0 102021.0 116618.0 106437.0 107866.0 98809.0 93089.0 88844.0 112659.0 64364.0 True False 144776.5926071575 101784.77664265156 107030.11819849786 114264.73204342315 101521.53395271531 94583.16940502902 97908.69293202487 92972.0165809679 99970.15706813656 75489.23164036093 1.9178442999246468 1.3483350463489352 1.4178196793471314 1.5136560481605246 1.3448478908405792 1.2529359135039781 1.2969888658884852 1.2315930969319824 1.3242969215053806 1.0 16.203983241642195 -1.5228787452803376 0.2541310469141863 1.1479180136305702 4.901982308460478 0.6823475060670388 0.12616130355148575 32.209007221784496 0.4407729981944971 0.15724815166930872 51.966480137953134 0.029999999999999995 1.5228787452803376 3.7540642948299077 TAAKGEAAAERPGEAAVASS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 1 TAAKGEAAAERPGEAAVASSPSK 23 2 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 TAAKGEAAAERPGEAAVAS(0.201)S(0.769)PS(0.03)K 59.537 0.016613 5285200.0 7740.8 7320.5 8158.6 14586.0 12386.0 8152.7 6139.4 8955.3 7762.3 10277.0 True False 10202.213381357757 9686.708464820123 8050.41163326546 11223.423051453572 10666.417697922625 7642.910380196913 6685.794706406261 7571.464157321755 8172.599330950469 9917.205358075342 1.0287387437278728 0.9767578783606079 0.8117621187212992 1.1317122764141017 1.0755467203507305 0.7706717874883446 0.674161163856729 0.7634675177071426 0.824082897940166 1.0 13.275717914944611 -6.7718920377451015 24.991985861523855 0.7834236251112996 0.9996547494348472 0.44160693073639923 0.10996828726725072 188.42008353686288 450503.93981877156 0.03912885191802098 0.03487373280005607 1.690861214443894e-07 6.7718920377451015 0.21623112432354763 TAAKGEAAAERPGEAAVASS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 1 TAAKGEAAAERPGEAAVASSPSK 23 2 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 TAAKGEAAAERPGEAAVAS(0.413)S(0.545)PS(0.042)K 58.093 0.0022866999999999996 21664000.0 127420.0 43103.0 52064.0 50955.0 37214.0 43200.0 26122.0 20088.0 53498.0 26035.0 True False 125602.96743403358 43003.197651740404 47783.49889285188 54702.40068089706 35025.145685539035 41352.436704118576 27474.469344072368 21021.361814849413 47472.49188108521 30535.1150605431 4.11339427360912 1.408319489429674 1.5648704384479892 1.7914588031660137 1.1470448241669757 1.354258420907456 0.8997663604541107 0.6884323760748758 1.5546852136289564 1.0 14.898181661015604 -3.1865427689821204 1.3681936662776433 1.2078492573892141 199.9999999999944 0.8651507481979996 0.33491130461462804 35.018902508259636 1.2386962687254481 0.10046227131012715 20898.474663258778 0.000650814515978119 3.1865427689821204 198.79215074260517 up TAANKS(ph)PCETISSPSSTLESK ddPTM_PC-9_AZD4547_30min_R2 2 TAANKSPCETISSPSSTLESK 21 1 Q9C0D5 Q9C0D5 TANC1 Protein TANC1 1 T(0.002)AANKS(0.983)PCET(0.015)ISS(0.001)PSSTLESK;T(0.008)AANKS(0.947)PCET(0.029)IS(0.011)S(0.004)PSSTLESK 98.92399999999999 0.00011540000000000001 37635000.0 66237.0 72346.0 86117.0 103514.0 95601.0 94767.0 75535.0 84883.0 74586.0 86114.0 True False 87298.9881848122 95730.42969686167 84975.0323121518 79650.4465753575 82328.45134337968 88841.20450895057 82257.4686693158 71766.28276729345 78528.46368966314 83099.1750710617 1.0505397690188747 1.1520021662669748 1.022573716760557 0.9584986434250997 0.9907252541674096 1.0690985131077246 0.9898710618844757 0.8636220841653722 0.9449969102883398 1.0 16.34254653492298 -5.44382274676083 0.5001071450933076 0.9476408263042804 1.1516752760110458 0.389439368355018 0.05758038425390522 2.6002753400358762 0.8016867490108982 0.04412095934203498 0.2903665440533962 3.598961934564407e-06 5.44382274676083 0.20403444970676543 TAANKS(ph)PCETISSPSSTLESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TAANKSPCETISSPSSTLESK 21 1 Q9C0D5 Q9C0D5 TANC1 Protein TANC1 1 T(0.008)AANKS(0.882)PCET(0.106)IS(0.004)SPSSTLESK;T(0.026)AANKS(0.968)PCET(0.004)IS(0.001)SPSSTLESK 96.133 0.00015462 29757000.0 56364.0 63059.0 50437.0 72374.0 76657.0 66362.0 71132.0 70274.0 64422.0 51379.0 True False 65905.31196025592 69319.08077758734 51639.60936338765 68319.119419674 61636.61113687884 62881.85989637578 64393.86200891686 68429.38196145782 65364.04987554987 60693.60598405979 1.0858691107851608 1.1421150490842955 0.850824539523158 1.1256394856093561 1.015537141640039 1.036054109437668 1.060966158870654 1.1274561933168004 1.0769511683441038 1.0 15.88925691743117 -7.522759390771625 24.999496014793444 1.0801644366431662 1.0416356128332385 0.014316486276592544 0.08056282729215965 16.67263730352248 3494744.5139765916 0.036718435245878665 0.02147307989590584 3.0008245850402856e-08 7.522759390771625 -0.038528823809927726 TAANKS(ph)PCETISSPSSTLESK ddPTM_PC-9_Lapatinib_30min_R1 2 TAANKSPCETISSPSSTLESK 21 1 Q9C0D5 Q9C0D5 TANC1 Protein TANC1 1 T(0.013)AANKS(0.79)PCET(0.19)IS(0.004)S(0.002)PSSTLESK;TAANKS(0.992)PCET(0.004)IS(0.004)SPSSTLESK 118.04 1.2597e-06 37384000.0 109810.0 99999.0 98686.0 92405.0 98983.0 96158.0 94267.0 90195.0 91374.0 72822.0 True False 108244.08926331227 99767.45845942006 90572.41801897642 99200.77195404364 93161.01454806556 92045.54649524612 99147.68400802658 94385.78897303583 81082.4979091232 85409.18567078453 1.2673588726222778 1.1681115757733653 1.0604528928316201 1.1614766160682026 1.0907610676345865 1.077700785604512 1.1608550442126684 1.105101146109181 0.9493416577188917 1.0 16.382103618119295 -1.5228787452803376 0.1600146945835176 0.9859776693512954 1.8749062097733733 0.5588850858021401 0.057453912865514316 55.55301538927375 0.575411903222624 0.18026418168254882 11.635816961882469 0.029999999999999995 1.5228787452803376 0.8889285404220779 TAAPS(ph)PSLLYK ddPTM_PC-9_AZD4547_30min_R2 2 TAAPSPSLLYK 11 0 Q9BTC0;Q9BTC0-1;Q9BTC0-2;Q9BTC0-3 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 T(0.021)AAPS(0.81)PS(0.17)LLYK;T(0.002)AAPS(0.946)PS(0.053)LLYK 163.71 0.00027484 22875000.0 168777.0 166993.0 218360.0 280680.0 263660.0 233870.0 178090.0 235380.0 192332.0 199654.0 True False 222444.57522031534 220970.22152389956 215464.40372611044 215973.5624627721 227055.3601028812 219246.07192913382 193939.66499395578 199007.42949431026 202498.27686643967 192664.17422994805 1.1545715549317637 1.1469191011099331 1.1183418224342525 1.1209845490267634 1.1785032739500738 1.137970112011898 1.0066202799202586 1.0329238961509857 1.051042715521955 1.0 17.555728802863655 -7.254213921117177 24.303142515728723 1.0253903794114894 1.1425736439663559 0.8910156419816773 0.02059130565516619 122.1135264114199 410735.2887792899 0.008241784891057426 0.006242794930942974 5.569113626527272e-08 7.254213921117177 0.1171832645548665 TAAPS(ph)PSLLYK ddPTM_PC-9_Lapatinib_30min_R1 2 TAAPSPSLLYK 11 0 Q9BTC0;Q9BTC0-1;Q9BTC0-2;Q9BTC0-3 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 TAAPS(0.833)PS(0.167)LLYK;TAAPS(0.993)PS(0.007)LLYK 155.88 0.00069335 11384300.0 110459.0 92271.0 111959.0 82365.0 95033.0 102482.0 86294.0 82697.0 92560.0 77962.0 True False 108883.83440430036 92057.3521686135 102754.16319423803 88422.39686158532 89443.34578206677 98099.08375721029 90761.88108021514 86539.40452024114 82134.91809998966 91437.62782216494 1.1907989850312628 1.0067775636924206 1.1237623464388466 0.9670241777658113 0.9781897005904745 1.072852457939975 0.9926097520457984 0.946430988876371 0.8982616900312865 1.0 16.480500355569127 -1.5228787452807604 0.3708243162638908 0.962526025563771 3.564165507540353 0.5268752064810223 0.05704943240667409 55.795637463782626 0.7701371233622394 0.045464968265798385 103.4737163104864 0.029999999999970793 1.5228787452807604 2.601639481976582 TAAPSPS(ph)LLYK ddPTM_PC-9_Lapatinib_30min_R1 1 TAAPSPSLLYK 11 0 Q9BTC0;Q9BTC0-1;Q9BTC0-2;Q9BTC0-3 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 T(0.017)AAPS(0.108)PS(0.874)LLYK 114.72 0.0014301 8340700.0 60179.0 49414.0 55556.0 50536.0 48484.0 49008.0 43321.0 41615.0 46841.0 41173.0 True False 59320.83642452296 49299.58491898711 50988.400132361676 54252.58602315404 45632.26644321154 46912.04208322785 45563.94940871904 43548.58482302661 41565.273322402936 48289.69819042603 1.2284366779555473 1.0209130884309667 1.0558856659508113 1.1234815717674171 0.9449689717103812 0.9714710143400457 0.9435542386088592 0.9018193622021975 0.8607482523186222 1.0 15.559427826275252 -5.857958936612198 0.5687152411282281 0.9088092207840558 1.1820005911885807 0.6335231152659427 0.06255810941094908 0.9361030615173325 0.510875142250339 0.04217191369751187 0.1474106855140871 1.3868869555312665e-06 5.857958936612198 0.2731913704045249 TAAQVLIR ddPTM_PC-9_Lapatinib_30min_R1 1 TAAQVLIR 8 0 O60218 O60218 AKR1B10 Aldo-keto reductase family 1 member B10 0 98.62899999999999 0.025099 15132000.0 145430.0 127310.0 142170.0 129120.0 147360.0 146440.0 148110.0 123980.0 112400.0 122680.0 False True 143356.14153140417 127015.22151690292 130481.33139207028 138615.91553169306 138692.57452090693 140177.102568313 155778.4110922043 129740.56341124242 99740.32837552766 143885.0745391756 0.9963239202574313 0.8827546701678253 0.9068441032536986 0.9633793913346591 0.9639121706341062 0.9742296274805555 1.0826585842285574 0.9016957723152719 0.6931944032066464 1.0 17.134557420892378 -8.0024536398932 24.956284783133963 0.8302131514068541 0.9637779222197359 0.24299027601680157 0.08526969403545093 106.3898604250308 1082096.6171672754 0.0460763271891258 0.02153025605386819 9.943662149827108e-09 8.0024536398932 0.13356477081288176 TAATASDS(ph)TRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TAATASDSTRR 11 1 F2Z363;F8WD80;C9J9P8;C9IZ93;C9JSK8;C9JFD2;C9JF62;F8WFB7;H3BSR4;F8WDQ9;F8WB39;H3BUI7;G5E9R6;Q969M7-4;Q969M7-5;Q969M7-3;Q969M7-6;Q969M7;Q969M7-2 F2Z363 UBE2F;UBE2F-SCLY NEDD8-conjugating enzyme UBE2F 1 TAATAS(0.116)DS(0.442)T(0.442)RR 80.905 0.0071737 585970.0 3551.4 4559.7 4912.2 3870.0 6879.5 5621.9 3089.6 5829.8 5096.9 4927.4 True False 4152.5818766526945 5012.356881992507 5029.3254776222375 3653.1764467092826 5531.511359903964 5327.0776672106695 2796.930721233055 5676.773927183688 5171.432520112544 5820.69861472306 0.713416404372668 0.8611263378787715 0.8640415542046622 0.6276182102039817 0.9503174319852918 0.9151955838662029 0.4805146093904277 0.97527364031951 0.8884556412235051 1.0 12.506976604034378 TAATASDST(ph)RR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TAATASDSTRR 11 1 F2Z363;F8WD80;C9J9P8;C9IZ93;C9JSK8;C9JFD2;C9JF62;F8WFB7;H3BSR4;F8WDQ9;F8WB39;H3BUI7;G5E9R6;Q969M7-4;Q969M7-5;Q969M7-3;Q969M7-6;Q969M7;Q969M7-2 F2Z363 UBE2F;UBE2F-SCLY NEDD8-conjugating enzyme UBE2F 1 TAATAS(0.046)DS(0.118)T(0.835)RR 72.705 0.022555000000000002 742470.0 3003.0 4006.1 5136.9 4045.0 7871.9 6001.1 3590.2 4567.9 5900.8 2908.0 True False 3511.348588046413 4403.799132607449 5259.383177801734 3818.371764066938 6329.457703906969 5686.391751667224 3250.1102652029135 4447.997465090115 5987.0880367831605 3435.1973802846655 1.0221679278747695 1.281963929607596 1.5310279426697464 1.1115436294814942 1.8425310115317053 1.6553318840724103 0.9461203841898557 1.2948302448698075 1.7428658018733778 1.0 11.746177280758392 -4.840088433509747 3.226370613956461 1.4015183592789606 0.9919024483138439 0.12504008413813994 0.2928306914856494 0.6201396941943653 10.476844096258699 0.07469254632605353 0.5937637926849473 1.4451454720522855e-05 4.840088433509747 -0.40961591096511674 TAAYGHFGR ddPTM_PC-9_AZD4547_30min_R2 2 TAAYGHFGR 9 0 P31153 P31153 MAT2A S-adenosylmethionine synthase isoform type-2 0 ; 105.1 0.0022314 13515200.0 77064.0 66036.0 113766.0 172716.0 145674.0 111191.0 99568.0 120219.0 99069.0 112664.0 False True 101568.74896922208 87380.84559563713 112257.38850661622 132898.99463559946 125449.67961627514 104238.20919259566 108429.35911122555 101641.91590779378 104305.58508662801 108719.66765225292 0.9342260803638259 0.8037262022832021 1.0325398424292367 1.2224006705087227 1.1538821109859743 0.9587796894855171 0.9973297513936858 0.9348990675072905 0.9593994107879023 1.0 16.730253425452588 -5.2780065573169495 23.217269030911766 1.0373208458620307 0.8689761658567883 0.3412996968192866 0.09061007594959762 337.96855973144693 473630.497457919 0.026711839903005564 0.05592908642310989 5.272219009550966e-06 5.2780065573169495 -0.1683446800052424 TAAYGHFGR ddPTM_PC-9_Lapatinib_30min_R1 1 TAAYGHFGR 9 0 P31153 P31153 MAT2A S-adenosylmethionine synthase isoform type-2 0 90.62899999999999 0.007071600000000001 5764100.0 49461.0 39131.0 50176.0 45035.0 49183.0 44998.0 35540.0 39727.0 47400.0 43445.0 False True 48755.67706996347 39040.39457370149 46050.7229649611 48347.024132356 46290.15263749842 43073.540435461284 37380.08730144444 41572.861450543736 42061.31285587195 50954.41036317631 0.9568490091919146 0.7661828347230796 0.9037632392708641 0.9488290373250082 0.9084621391468667 0.84533488128811 0.733598662706894 0.8158834761158885 0.8254695237582179 1.0 15.63691940393285 -6.909738180337238 5.586099970620777 0.8232858642033718 0.8923478308198789 0.0753434925992128 0.07939816253284868 0.41666958116793584 20.437996672279606 0.02777128965279177 0.02442240991703038 1.2310106767797212e-07 6.909738180337238 0.0690619666165071 TADEDRGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TADEDRGPR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 85.161 0.016397 3758700.0 19832.0 19173.0 23998.0 23829.0 39894.0 36869.0 25504.0 26660.0 33053.0 30492.0 False True 23189.16590014537 21076.368730057296 24570.203332921814 22493.938384660338 32077.057081475232 34935.524735834915 23088.07648703 25960.203248604947 33536.33759486747 36019.958225460796 0.643786585064778 0.5851302935481867 0.6821274799689886 0.6244854101124537 0.8905356547249265 0.9698935383867451 0.6409801017123373 0.7207171947871642 0.931048764269866 1.0 15.136508887613308 -3.615579580065498 0.1186969206351174 1.0854571827696011 5.341410488073459e-16 0.49678654236629105 0.10790620157887255 55.541624323587456 0.7647105973549561 1.0588968993993961 9.676398024465126 0.00024233738651494095 3.615579580065498 -1.0854571827696007 TADEDRGPR ddPTM_PC-9_Lapatinib_30min_R1 1 TADEDRGPR 9 1 Q14152-2;Q14152 Q14152-2 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 75.043 0.034412 5253600.0 27611.0 40619.0 28294.0 30249.0 35621.0 25430.0 32723.0 33177.0 40230.0 24490.0 False True 27217.262076762734 40524.949201123934 25967.77653799845 32473.612367705915 33525.84281358054 24342.418180225355 34417.23682513132 34718.52453859316 35698.87375931916 28723.063869126217 0.9475751681915091 1.410885321488398 0.9040740450363526 1.1305761988229632 1.1672098410649263 0.8474868242169137 1.198243926272978 1.208733326527583 1.2428644075707775 1.0 14.809922028189334 TADGGEPAGASS(ph)PAGR ddPTM_PC-9_Lapatinib_30min_R1 2 TADGGEPAGASSPAGR 16 0 O76081-6 O76081-6 1 TADGGEPAGAS(0.423)S(0.577)PAGR;TADGGEPAGAS(0.383)S(0.617)PAGR 97.823 0.01295 0.0 18518.9 18500.2 14852.8 15176.099999999999 16504.4 16020.6 15382.0 13934.0 22621.0 15206.6 True False 18254.817090049666 18457.363923548895 13631.660117466006 16292.201019985505 15533.643640898856 15335.436283842633 16178.404695295962 14581.424508567894 20073.184770309686 17835.04054847917 1.0235366182896788 1.034893297460027 0.7643189865709841 0.913493915289964 0.8709620591371989 0.8598486918018426 0.9071134237861617 0.8175717049217072 1.125491400804321 1.0 14.122426875366695 -8.265071810933525 24.99994799105746 1.0627457065057162 0.8975282151523226 0.38259125525651994 0.08320539168429089 347.9897866160664 2394958.2742980905 0.07160735381767495 0.0213217155177386 5.431605120497047e-09 8.265071810933525 -0.1652174913533936 TADGRVS(ph)PAGGTLDDKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TADGRVSPAGGTLDDKPK 18 2 C9JA69;Q8WY36-2;Q8WY36 C9JA69 BBX HMG box transcription factor BBX 1 T(0.445)ADGRVS(0.554)PAGGT(0.001)LDDKPK 71.65100000000001 0.024778 18625000.0 51843.0 44317.0 52960.0 50984.0 63419.0 43336.0 46080.0 41785.0 44815.0 43773.0 True False 60618.99595407603 48716.498879150335 54222.76725191843 48127.53177235821 50992.50220710076 41063.38387133208 41714.968809690305 40688.188024867115 45470.334593349595 51708.69839312263 1.1723171891354065 0.9421335363883331 1.0486198441833179 0.9307434390721249 0.9861494060326779 0.7941291339252431 0.8067302041243894 0.7868731816749566 0.8793556211308009 1.0 15.658119369433193 -5.9248012920266975 0.8661241251122669 0.8412591041343201 1.085960051072311 0.496315707483197 0.08321264808900669 0.5719058444561232 0.8399886863525031 0.037144964755256624 0.09609121906043307 1.1890461415658844e-06 5.9248012920266975 0.24470094693799094 TADS(ph)VSPLEPPTKDK ddPTM_PC-9_AZD4547_30min_R2 1 TADSVSPLEPPTKDK 15 1 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 T(0.038)ADS(0.536)VS(0.426)PLEPPTKDK 75.143 0.0072066000000000005 5536300.0 22413.0 17636.0 28992.0 47181.0 47701.0 34966.0 28495.0 35210.0 26812.0 35202.0 True False 29539.867780639146 23336.492109223105 28607.54713696371 36304.14938918353 41078.53952919483 32779.57049247061 31030.999797870558 29769.10354530825 28229.227582217147 33969.58869465489 0.8695974521848491 0.6869818860331123 0.8421517079323689 1.0687250209448658 1.209273974390468 0.96496813038035 0.9134935390828939 0.8763457165435863 0.831014700706665 1.0 15.051956129654286 -5.578556815436401 6.120586658941387 0.9807368200339797 0.7746733507914946 0.3823934404722763 0.10735069095323661 0.20672547768277919 16.15682460495431 0.03265128225984254 0.05762981546624762 2.639023056513003e-06 5.578556815436401 -0.2060634692424851 TADS(ph)VSPLEPPTKDK ddPTM_PC-9_Lapatinib_30min_R1 1 TADSVSPLEPPTKDK 15 1 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 T(0.162)ADS(0.603)VS(0.235)PLEPPTKDK 52.644 0.039994999999999996 4580400.0 28800.0 17263.0 34446.0 28848.0 25208.0 31895.0 25479.0 20530.0 36146.0 26076.0 True False 28389.306718726843 17223.028584135565 31613.982845405197 30969.57815410693 23725.31500083483 30530.925200876416 26798.177950295532 21483.898748449752 32074.856845745737 30583.20185591404 0.9282647007490175 0.5631532193809542 1.0337041554493689 1.01263361174586 0.7757629535524561 0.9982906742307782 0.8762384683117612 0.7024738236913965 1.0487736698354637 1.0 14.900451834640432 -1.5231228843023552 0.02422065055900179 1.5411503531122372 0.0002518130977452641 0.07249369276792306 0.14959258888229643 6621.51632230975 12.383376261925147 274.3038225875676 560.3690458205522 0.029983140213134463 1.5231228843023552 -1.540898540014492 TADSSS(ph)SEDEEEYVVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TADSSSSEDEEEYVVEK 17 0 P45973;F8VNY3 P45973 CBX5 Chromobox protein homolog 5 1 TADS(0.281)S(0.089)S(0.616)S(0.014)EDEEEYVVEK 132.15 2.4606999999999997e-05 10759000.0 13134.0 13032.0 17523.0 19485.0 24531.0 19733.0 21670.0 18870.0 18633.0 14517.0 True False 15357.326791675529 14325.730834512431 17940.814776347568 18393.318621222337 19724.326647256938 18698.16674203886 19617.260722786225 18374.682494417673 18905.472374827244 17148.81718349123 0.8955327138515229 0.835377197227543 1.0461838029050061 1.0725706866202505 1.15018583708765 1.0903473132852075 1.1439424954434356 1.0714839570455366 1.1024359390236609 1.0 14.065821451436753 -5.376272644160232 3.497478706623731 1.0962608882207763 0.8643149072226155 0.8102570498692496 0.04263563993225762 0.08649850077777074 1.9212263708485695 0.010970395752065135 0.02578426540482782 4.204625848279901e-06 5.376272644160232 -0.23194598099816077 TADSSSS(ph)EDEEEYVVEK ddPTM_PC-9_AZD4547_30min_R2 2 TADSSSSEDEEEYVVEK 17 0 P45973;F8VNY3 P45973 CBX5 Chromobox protein homolog 5 1 TADSSS(0.015)S(0.985)EDEEEYVVEK;TADSSS(0.017)S(0.982)EDEEEYVVEK 293.52 1.1891999999999995e-222 10373000.0 15709.3 17420.6 23013.1 25482.9 24530.0 22280.9 21226.3 29252.0 23512.0 22923.1 True False 20704.530626261294 23051.468271599664 22707.931257507586 19608.21111188033 21124.432918621198 20887.671800768996 23115.39957920828 24731.775544088512 24754.796319300654 22120.56924624861 0.9359854349034231 1.0420829597551573 1.026552752992945 0.886424345305022 0.9549678710100851 0.9442646601109191 1.0449730891590134 1.1180442631820033 1.119084958606966 1.0 14.433100891621748 -7.446462799255997 4.090638410862709 1.0883954552013995 0.9677515942021591 0.5002505966678497 0.052055175496955125 0.18955592622021103 5.95985627496952 0.024461388153408238 0.015498073650577692 3.577150403756848e-08 7.446462799255997 -0.1206438609992404 TADSSSS(ph)EDEEEYVVEK ddPTM_PC-9_Lapatinib_30min_R1 3 TADSSSSEDEEEYVVEK 17 0 P45973;F8VNY3 P45973 CBX5 Chromobox protein homolog 5 1 TADSSS(0.012)S(0.988)EDEEEYVVEK;TADSSS(0.026)S(0.974)EDEEEYVVEK;TADSSS(0.004)S(0.996)EDEEEYVVEK 354.25 0.0 24325000.0 144878.0 115238.0 126256.0 109368.0 121835.0 121323.0 109614.0 116390.0 128769.0 116271.0 True False 142812.01315262864 114971.17349120187 115875.71904225377 117411.28756095296 114668.90483682606 116134.2981077262 115289.27657457873 121797.90430258482 114265.67922231583 136368.2874286312 1.047252376967554 0.8430931828734185 0.8497262906736854 0.8609867424081317 0.8408766216767106 0.8516224724792079 0.8454258592556994 0.8931541680196589 0.8379197346899083 1.0 17.057148657737166 -4.757705071421139 24.973070833346117 0.8628189737074342 1.0472526434502667 0.5633389293373289 0.04672479822523353 69.16024493861192 462438.9315334284 0.01042580951410403 0.07560173562213948 1.7470081401686495e-05 4.757705071421139 0.18443366974283248 TADSVS(ph)PLEPPTK ddPTM_PC-9_AZD4547_30min_R2 2 TADSVSPLEPPTK 13 0 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 TADS(0.009)VS(0.99)PLEPPTK;TADS(0.024)VS(0.976)PLEPPTK 126.95 0.00012309 10158000.0 46713.0 60517.0 60282.0 66447.0 57386.0 70201.0 66332.0 75288.0 58465.0 65179.0 True False 61566.76230924001 80077.93677556443 59482.621292440934 51128.67074591636 49418.94445446375 65811.32037241696 72235.41949788912 63653.96954612798 61555.34054133686 62897.10304894353 0.9788489346056477 1.2731577909598093 0.9457132110862784 0.8128938896618253 0.7857109796616274 1.0463330929757721 1.1484697386090892 1.0120334079074436 0.9786673401068635 1.0 15.94070594970377 -5.2991814478114065 24.987423108511884 0.9641037662150242 1.126003485703679 0.2221569322517376 0.1195348717949702 768.4020702040635 508725.04964449484 0.03411209107226611 0.07101222839064969 5.021327551152742e-06 5.2991814478114065 0.16189971948865467 TADSVS(ph)PLEPPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TADSVSPLEPPTK 13 0 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 TADS(0.008)VS(0.992)PLEPPTK 145.61 1.6597000000000002e-07 0.0 21402.0 29856.0 28109.0 29244.0 34349.0 29072.0 35412.0 27695.0 26215.0 21147.0 True False 25024.935891231904 32819.90636856993 28779.225163976145 27605.553490327227 27618.560026359646 27547.413141668956 32057.518999321906 26968.035595278063 26598.344781092495 24980.78370044012 1.0017674461826835 1.313806114417127 1.1520545355616327 1.1050715550545704 1.1055922167034757 1.1027441521453796 1.2832871611933099 1.0795512229987778 1.0647522151446305 1.0 14.608531117624343 -7.986147903355169 24.99405231126925 1.0456345869017971 1.154824168157262 0.2399825130930624 0.08675912959249607 316.36204129002476 570828.1605695992 0.04630759654197814 0.02222999135503342 1.0324097483578746e-08 7.986147903355169 0.10918958125546485 TADSVS(ph)PLEPPTK ddPTM_PC-9_Lapatinib_30min_R1 2 TADSVSPLEPPTK 13 0 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 T(0.001)ADS(0.011)VS(0.989)PLEPPTK;TADS(0.004)VS(0.996)PLEPPTK 165.51 0.00029513 10397200.0 38010.0 65437.0 65666.0 59307.0 85078.0 79258.0 86621.0 85405.0 74927.0 72260.0 True False 37467.97042981967 65285.48464693733 60267.19495809024 63668.63462235232 80073.87930978369 75868.32009942194 91105.81154019195 89373.22808628109 66487.93224371139 84750.04471960211 0.442099712794058 0.7703297958477329 0.711116969406753 0.7512519295181704 0.9448240360782151 0.8952009447361874 1.0749942591961819 1.054550807400455 0.7845179605944583 1.0 16.370926509057796 -4.438260589721544 0.47002954878306036 0.9915092361299259 2.9419099499411513e-14 0.7150766302023326 0.09719380057169417 3.6240828413597894 0.48724526537025864 0.06520371534167776 2.1330135886259494 3.645351492609844e-05 4.438260589721544 -0.9915092361298965 down TADSVS(ph)PLEPPTKDK ddPTM_PC-9_AZD4547_30min_R2 1 TADSVSPLEPPTKDK 15 1 Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;Q9UMZ2-6;Q9UMZ2-9 Q9UMZ2-4 SYNRG Synergin gamma 1 T(0.006)ADS(0.086)VS(0.908)PLEPPTKDK 66.977 0.014518999999999999 5834000.0 25354.0 15371.0 31796.0 43390.0 42108.0 36423.0 28620.0 35222.0 32456.0 36140.0 True False 33416.04460403892 20339.375153712183 31374.36426486265 33387.105868817394 36262.03103698743 34145.464052143725 31167.124555713468 29779.24922104083 34171.55789976278 34874.749600159856 0.958173033130129 0.5832120771304105 0.8996298073698238 0.9573432426498155 1.0397789648021218 0.9790884362933809 0.8936874074522562 0.8538914131989733 0.9798366523499326 1.0 15.089895238013726 -5.505137670121628 23.727201381842196 0.9513191659276645 0.7633745986923419 0.36333123619655416 0.09748547550982226 363.7544372514806 486489.0919755019 0.024693362911805655 0.04965463926743923 3.125088565860867e-06 5.505137670121628 -0.1879445672353226 TAENATSGETLEENEAGD ddPTM_PC-9_AZD4547_30min_R2 2 TAENATSGETLEENEAGD 18 0 Q9UQ80;Q9UQ80-2 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 0 ; 166.62 4.4283e-08 10445000.0 48891.0 50691.0 67038.0 88140.0 78416.0 62011.0 54260.0 71265.0 57177.0 63714.0 False True 64437.3210040257 67075.87443346727 66149.03231814886 67820.68474942536 67529.29195868746 58133.442367116484 59089.034884451845 60252.631756784845 60199.259490841025 61483.39225303231 1.0480443359214244 1.0909592326561834 1.0758845583196728 1.103073240824322 1.0983338668233122 0.9455145566443496 0.9610568434687763 0.9799822285149408 0.979114152372945 1.0 15.90790914528756 -6.757850401575393 24.99999998548813 0.9711276447187316 1.0843779427883935 0.8908090433076822 0.019269471849060513 27.87562174865928 194175.25078528756 0.006557706366953534 0.006312403133838101 1.7464236278226081e-07 6.757850401575393 0.11325029806966191 TAENATSGETLEENEAGD ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TAENATSGETLEENEAGD 18 0 Q9UQ80;Q9UQ80-2 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 0 ; 170.0 1.446e-24 5970100.0 99012.0 95246.0 109801.0 125409.0 120691.0 123693.0 131457.0 114566.0 130545.0 85505.0 False True 115772.77602386012 104701.3934211152 112419.07226261156 118382.74031146381 97042.46493759254 117206.32133091832 119004.44129373858 111558.76389271072 132453.97365812425 101006.37964279225 1.1461927101366174 1.036581984141896 1.1129898196547598 1.1720323085543987 0.9607557986018502 1.1603853315544717 1.1781873750410246 1.1044724529998684 1.3113426510933863 1.0 16.624086892051018 TAENATSGETLEENEAGD ddPTM_PC-9_Lapatinib_30min_R1 2 TAENATSGETLEENEAGD 18 0 Q9UQ80;Q9UQ80-2 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 0 ; 179.59 4.8958e-08 18719300.0 138942.0 124120.0 128810.0 116715.0 125810.0 125576.0 115917.0 113177.0 132054.0 101682.0 False True 136960.66160115745 123832.60776590988 118219.7390209788 125298.61044982652 118410.10315197673 120205.40721195344 121918.61507376294 118435.61659295177 117180.68792973229 119257.59821725161 1.1484439033532787 1.0383624156200428 0.9912973327336163 1.0506551559219732 0.9928935759402852 1.0079475774195554 1.0223131850405351 0.9931075114995823 0.9825846711776317 1.0 16.86372166151569 -4.76888801883211 2.8352011179670136 1.0067909544784672 1.1767274611695056 0.8424918340445691 0.01858572461427196 0.16230008579454128 1.7607652125584776 0.004746185580004327 0.06582095307085929 1.702597460032032e-05 4.76888801883211 0.16993650669103832 TAES(ph)QTPTPSATSFFSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TAESQTPTPSATSFFSGK 18 0 P55265-5;P55265;P55265-4;A0A3B3ITG9;A0A3B3ISX1;A0A3B3IRQ9;P55265-3;P55265-2 P55265-5 ADAR Double-stranded RNA-specific adenosine deaminase 1 T(0.004)AES(0.494)QT(0.494)PT(0.007)PS(0.001)ATSFFSGK 149.52 9.0893e-05 5897100.0 17275.0 20746.0 19529.0 28169.0 28918.0 21944.0 36059.0 24175.0 26709.0 23420.0 True False 20199.31630319742 22805.525774462472 19994.64542414492 26590.78225513019 23251.725489599943 20793.218009795786 32643.230475447555 23540.431865529805 27099.568596536308 27665.86060738201 0.7301170417163054 0.8243201286273139 0.7227190835628587 0.9611406141486537 0.8404482990634221 0.7515839938934553 1.179910176614475 0.8508837733118837 0.9795310177087136 1.0 14.755819182227375 -6.202712272856859 0.44752666214611336 0.9985073067203593 0.7130275143084475 0.3631292978191104 0.1099666433555646 1.89567965366729 0.682719977064703 0.09788322016690758 0.25221868980142237 6.270291440775122e-07 6.202712272856859 -0.2854797924119118 TAESQT(ph)PTPSATSFFSGK ddPTM_PC-9_AZD4547_30min_R2 3 TAESQTPTPSATSFFSGK 18 0 P55265-5;P55265;P55265-4;A0A3B3ITG9;A0A3B3ISX1;A0A3B3IRQ9;P55265-3;P55265-2 P55265-5 ADAR Double-stranded RNA-specific adenosine deaminase 1 TAES(0.006)QT(0.957)PT(0.009)PS(0.028)ATSFFSGK;T(0.24)AES(0.018)QT(0.449)PT(0.174)PS(0.052)AT(0.052)S(0.015)FFSGK;TAES(0.001)QT(0.956)PT(0.042)PS(0.001)ATSFFSGK 214.59 5.046699999999999e-27 73659000.0 308895.0 339707.0 340744.0 353703.0 307146.0 381971.0 301718.0 388380.0 293823.0 279753.0 True False 407117.18458486255 449510.64441754634 336225.5119218253 272162.2380068757 264504.07962588 358086.292986887 328570.3174947846 328364.795084544 309353.8839284565 269958.9326201857 1.5080708040791129 1.6651075037771688 1.245469111388406 1.0081616317167392 0.9797937673654225 1.3264472840789105 1.2171122263142935 1.2163509164059834 1.1459294231382107 1.0 18.04238042907778 -5.37708231131678 4.443348602186884 1.1417742732621594 1.5840588081135274 0.7230571084341018 0.11142462071441578 0.11717893770826611 3.6989200720462505 0.03123777657229834 0.06874201190256513 4.196794351085048e-06 5.37708231131678 0.442284534851368 TAESQT(ph)PTPSATSFFSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TAESQTPTPSATSFFSGK 18 0 P55265-5;P55265;P55265-4;A0A3B3ITG9;A0A3B3ISX1;A0A3B3IRQ9;P55265-3;P55265-2 P55265-5 ADAR Double-stranded RNA-specific adenosine deaminase 1 T(0.004)AES(0.021)QT(0.456)PT(0.334)PS(0.139)AT(0.037)S(0.008)FFS(0.001)GK;T(0.064)AES(0.288)QT(0.479)PT(0.163)PS(0.005)ATSFFSGK;TAES(0.014)QT(0.979)PT(0.006)PSATSFFSGK;TAES(0.002)QT(0.776)PT(0.003)PS(0.205)AT(0.014)SFFSGK 190.18 1.252e-10 51851000.0 89884.9 100736.0 100018.0 105942.7 138522.0 129773.0 204957.0 139423.0 140785.0 134001.8 True False 105100.63826230227 110736.40433896918 102402.80844037738 100007.07398986786 111379.60848849708 122967.4754276899 185541.98919982032 135763.29398087953 142843.7142859475 158295.26558233463 0.6639531376738235 0.6995560096607658 0.6469101148645174 0.6317755216617699 0.7036193285930263 0.7768234569449611 1.1721259540975582 0.8576585880912815 0.9023877862705233 1.0 17.27225858131412 -7.036439240665788 5.680610786062325 0.9733191091493344 0.6732227288971051 0.7764603945759501 0.07941701783269614 0.09449819663116074 8.416134386459587 0.03055596226615684 0.024280737183962158 9.195191097815234e-08 7.036439240665788 -0.3000963802522293 TAESQT(ph)PTPSATSFFSGK ddPTM_PC-9_Lapatinib_30min_R1 3 TAESQTPTPSATSFFSGK 18 0 P55265-5;P55265;P55265-4;A0A3B3ITG9;A0A3B3ISX1;A0A3B3IRQ9;P55265-3;P55265-2 P55265-5 ADAR Double-stranded RNA-specific adenosine deaminase 1 T(0.001)AES(0.009)QT(0.972)PT(0.017)PS(0.001)ATSFFSGK;TAES(0.009)QT(0.862)PT(0.029)PS(0.097)AT(0.003)SFFSGK;TAES(0.008)QT(0.956)PT(0.03)PS(0.006)ATSFFSGK 237.66 4.7364e-43 57456100.0 45735.0 54433.0 63796.0 54842.0 82835.0 102651.0 117247.0 114471.0 105992.0 94787.0 True False 45082.810513228214 54306.96373285357 58550.93913968156 58875.26362754892 77962.80815987592 98260.85602116841 123317.47596602286 119789.74055693121 94054.06481475913 111170.80665426138 0.40552742100212247 0.488500222020939 0.5266754906418338 0.5295928436558854 0.701288499258069 0.8838728347699895 1.1092613220801513 1.0775287520353658 0.8460320442511952 1.0 16.76241846191735 -6.609021328646121 1.607654765194834 1.0163123617602767 0.47819451487955955 0.913093736993131 0.0730120055161585 0.10221383884809472 0.5435395099968111 0.03077559350365813 0.03158702810565908 2.4602467759456075e-07 6.609021328646121 -0.5381178468807172 down TAESQTPTPS(ph)ATSFFSGK ddPTM_PC-9_AZD4547_30min_R2 1 TAESQTPTPSATSFFSGK 18 0 P55265-5;P55265;P55265-4;A0A3B3ITG9;A0A3B3ISX1;A0A3B3IRQ9;P55265-3;P55265-2 P55265-5 ADAR Double-stranded RNA-specific adenosine deaminase 1 T(0.019)AES(0.006)QT(0.45)PT(0.037)PS(0.484)AT(0.005)SFFSGK 195.86 1.6115e-14 34756000.0 36141.0 31995.0 34651.0 39371.0 27282.0 35166.0 28102.0 39127.0 28622.0 30770.0 True False 47633.08622050056 42336.758053673904 34191.50509943882 30294.62422588638 23494.36522159901 32967.064460854024 30603.023559212426 33080.8211990138 30134.90048702889 29692.751665659074 1.6041991243132325 1.4258280448503586 1.151510155893795 1.0202700162990752 0.7912491737426693 1.1102731344020849 1.0306563670421331 1.114104262599319 1.0148907998271235 1.0 14.857823175482672 -5.209527847129681 1.8561610234026802 1.0124180453396396 1.6127626882915997 0.8516621394904589 0.08439531842498915 0.15875759759474195 0.9344315417170914 0.025435426558544885 0.12165859210505926 6.17265711304257e-06 5.209527847129681 0.6003446429519601 TAESQTPTPS(ph)ATSFFSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TAESQTPTPSATSFFSGK 18 0 P55265-5;P55265;P55265-4;A0A3B3ITG9;A0A3B3ISX1;A0A3B3IRQ9;P55265-3;P55265-2 P55265-5 ADAR Double-stranded RNA-specific adenosine deaminase 1 TAES(0.005)QT(0.128)PT(0.128)PS(0.737)AT(0.002)SFFSGK 205.06 5.302399999999999e-67 0.0 5923.3 8601.3 9973.3 10010.0 16833.0 13337.0 19380.0 16907.0 12016.0 16363.0 True False 6925.997699492282 9455.180219988622 10211.101295950872 9449.17215285787 13534.694486701565 12637.584241553337 17544.186100950497 16463.20916444724 12191.711267961377 19329.48237056328 0.35831263179814016 0.48915848022851577 0.5282656358921064 0.48884765622321785 0.7002098777002661 0.6537983790398348 0.9076386922636067 0.8517149527769524 0.6307313891927101 1.0 14.238515383295162 -5.3256945570321435 0.23948507432144212 0.984725645747691 1.1458880235954515e-14 0.7718492951123124 0.09348223174585092 3.9444805294569356 0.24735266096823041 0.15895691272929716 1.1446131078343147 4.723951639560818e-06 5.3256945570321435 -0.9847256457476795 down TAESQTPTPSATSFFSGKSPVT(ph)TLLECMHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TAESQTPTPSATSFFSGKSPVTTLLECMHK 30 1 P55265-5;P55265;P55265-4;A0A3B3ITG9;A0A3B3ISX1;A0A3B3IRQ9;P55265-3;P55265-2 P55265-5 ADAR Double-stranded RNA-specific adenosine deaminase 1 T(0.001)AES(0.001)QT(0.001)PT(0.01)PS(0.07)AT(0.084)S(0.07)FFS(0.177)GKS(0.177)PVT(0.204)T(0.204)LLECMHK 42.056999999999995 0.041497000000000006 15523000.0 30435.0 29743.0 24691.0 37867.0 48520.0 38691.0 36828.0 40548.0 34822.0 28756.0 True False 35587.04438134952 32695.688475360905 25279.727081138943 35745.43475647044 39012.85430373434 36661.97584838723 33339.3852283697 39483.657964157275 35331.205873248255 33969.23516762923 1.047625717969122 0.9625088205258756 0.7441947678948362 1.0522884775025438 1.1484760875897315 1.079269982602494 0.9814582242976214 1.1623357950014424 1.0400942411243013 1.0 15.051941115214596 -5.969494649752288 24.9999100281164 1.075396955942168 0.9184982137263545 0.37224592835964243 0.08812600444230062 202.74833310872313 166156.15596479469 0.02478777900080369 0.036765794179254296 1.0727668635988958e-06 5.969494649752288 -0.15689874221581357 TAESS(ph)GGPSTSR ddPTM_PC-9_AZD4547_30min_R2 1 TAESSGGPSTSR 12 0 H7C309;A0A2R8Y762;A0A2R8YES7;A0A2R8Y5L2;A0A2R8Y6W8;P19447 H7C309 ERCC3 TFIIH basal transcription factor complex helicase XPB subunit 1 T(0.007)AES(0.228)S(0.759)GGPS(0.003)T(0.003)SR 67.952 0.035668 1787300.0 4649.6 5249.7 8871.5 16426.0 11666.0 6934.0 6832.6 14455.0 6367.0 8330.0 True False 6128.076082312041 6946.562861521231 8753.858113464868 12639.239479170203 10046.377269817976 6500.415883852634 7440.68816349992 12221.311892855174 6703.546621511881 8038.369235454671 0.7623531468650458 0.8641756378746783 1.0890092078445968 1.5723636360746613 1.249802910956942 0.8086734626696895 0.9256464769845889 1.520372047473371 0.8339436053701894 1.0 12.972687132514675 -5.236205807698334 3.7710724200130463 1.1475086796550362 0.794585033806942 0.2023904891942867 0.24848360868821104 0.3458095578727563 10.869959231894509 0.06755366812142095 0.1893913369150277 5.804892644247966e-06 5.236205807698334 -0.3529236458480942 TAETEEGTVQIQEGAVATGEDPTSVAIASIQSAATFPDPNVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TAETEEGTVQIQEGAVATGEDPTSVAIASIQSAATFPDPNVK 42 0 E9PME6;B1AQP1;P22415;E9PJ52 E9PME6 USF1 Upstream stimulatory factor 1 0 29.401 0.042204000000000005 5114700.0 4217.6 4438.9 4986.2 6320.6 6226.3 5358.3 6273.7 4793.9 5143.5 4172.2 False True 4931.556378602918 4879.564656331893 5105.089918268802 5966.477273661682 5006.301210868527 5077.3013152519525 5679.409718345357 4668.0652045569095 5218.713956954003 4928.586832882973 1.0006025146397204 0.9900535025123207 1.03581210829202 1.210585808056383 1.0157680853803879 1.0301738586356586 1.1523403991693884 0.9471407043926076 1.0588661890129103 1.0 12.26695832853697 -10.359022365875132 14.667536295136625 0.9999999999986283 1.0501736463739104 0.037848410467997584 0.07397511144672086 0.0 0.0 0.07224623604253491 0.017522286015098656 4.374995736428664e-11 10.359022365875132 0.0501736463752821 TAFDDAIAELDTLNEDSYK ddPTM_PC-9_Lapatinib_30min_R1 2 TAFDDAIAELDTLNEDSYK 19 0 P61981 P61981 YWHAG 14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed 0 ; 308.68 3.388499999999998e-227 981650.0 14549.400000000001 15064.099999999999 15511.900000000001 13972.9 14096.0 10684.5 16828.8 15075.1 10629.7 14670.9 False True 14341.922887966817 15029.220001985546 14236.571459665582 15000.513678227973 13266.900993802285 10227.54884178599 17700.11292004919 15775.544180358256 9432.471250296663 17206.74551725455 0.8335058406939913 0.873449310150753 0.8273831588541516 0.8717809921222921 0.7710290699945859 0.5943918233421903 1.0286729063494258 0.9168232403122882 0.54818450362028 1.0 14.070686631482074 -4.357463886762646 0.006808682254865716 1.6179944099076484 1.4682440634138273e-06 0.017767737544345907 0.14628018830008024 151392.88258302724 142.4951189815675 16000.065960893342 17902.746084023733 4.390723746602944e-05 4.357463886762646 -1.617992941663585 TAFQEALDAAGDK ddPTM_PC-9_AZD4547_30min_R2 1 TAFQEALDAAGDK 13 0 P10599-2;P10599 P10599-2 TXN Thioredoxin 0 93.228 0.019469999999999998 8484800.0 27539.0 21802.0 28192.0 23057.0 26130.0 31100.0 33216.0 36870.0 31396.0 34257.0 False True 36295.82915321559 28849.070138652874 27818.15565967445 17741.56487709894 22502.300536631537 29155.31208361939 36172.15965208172 31172.588688313394 33055.52846379566 33057.67285701929 1.0979547565311671 0.8726890807901263 0.8415037495226373 0.5366852335261036 0.680698264332104 0.8819529496138958 1.0942137339350284 0.9429758961902961 0.9999351317549511 1.0 15.012697547137693 -7.016308179763191 9.026331248819035 1.0023988964522061 0.7950394488352488 0.3226050265258703 0.13847124747757497 0.3221372292414122 160.3235644270693 0.056241205625160065 0.045670700109387126 9.631453233954775e-08 7.016308179763191 -0.20735944761695735 TAFQEALDAAGDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TAFQEALDAAGDK 13 0 P10599-2;P10599 P10599-2 TXN Thioredoxin 0 ; 137.62 0.00027878 6918200.0 40422.0 52353.0 43254.0 39629.0 42976.0 31465.0 40426.0 36315.0 33024.0 32717.0 False True 47264.646229108286 57550.25985107652 44285.33940170849 37408.71560895146 34555.16130579735 29814.920009033194 36596.556621105505 35361.769728923035 33506.91352473006 38648.33311237049 1.2229413902971122 1.4890748246178807 1.1458538010668748 0.9679257188191059 0.8940918927946467 0.771441291461289 0.9469116433741289 0.9149623510568557 0.8669691763240682 1.0 15.23811857216334 -5.628211721033011 2.473049328327463 0.894761865881817 1.3563668485332294 0.8197122334269527 0.08466058680654115 0.10137610670903557 1.2477564910353933 0.023343953931234902 0.04831507887902904 2.353901463766474e-06 5.628211721033011 0.46160498265141237 TAFQEALDAAGDK ddPTM_PC-9_Lapatinib_30min_R1 1 TAFQEALDAAGDK 13 0 P10599-2;P10599 P10599-2 TXN Thioredoxin 0 173.72 0.00087208 18994000.0 114790.0 87522.0 102570.0 91303.0 95731.0 75141.0 105990.0 110880.0 89646.0 98991.0 False True 113153.07355009236 87319.34818633564 94137.09053164994 98017.72719787937 90100.29079438747 71927.39459222619 111477.6435869471 116031.88958734075 79549.12346577006 116101.46245278396 0.9746050666339311 0.7520951617801248 0.8108174397022219 0.8442419684225867 0.7760478541002821 0.6195218653811321 0.9601743271087798 0.9994007580613249 0.6851690046378272 1.0 16.825026619423156 -10.652164339678247 5.384545083619697 1.0000035991679148 0.8243682268247009 0.16389676132060083 0.11879650287087705 5.148945159367739e-06 8.326474613604357e-07 0.1153869911478817 0.027984882472796926 2.2275920553572495e-11 10.652164339678247 -0.1756353723432139 TAFYNEDDS(ph)EEEQR ddPTM_PC-9_AZD4547_30min_R2 5 TAFYNEDDSEEEQR 14 0 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 TAFYNEDDS(1)EEEQR;TAFYNEDDS(1)EEEQR;TAFYNEDDS(1)EEEQR;TAFYNEDDS(1)EEEQR;TAFYNEDDS(1)EEEQR 245.39 9.219799999999998e-48 104327000.0 78397.1 87420.3 90648.9 101196.0 89741.0 103111.0 87821.8 122126.0 91688.4 93494.0 True False 103325.74703901944 115677.2023778587 89446.836357061 77866.82566261454 77282.01119241687 96663.4528699061 95637.77006663028 103254.2328762941 96534.86163842154 90220.80351735895 1.14525412112007 1.2821566409082337 0.9914214113583123 0.8630695208520568 0.8565874851419099 1.0714097979775536 1.0600412137565267 1.1444614639951356 1.0699845032952708 1.0 16.46117251447999 -5.270735095724541 24.820053326789317 1.0059462668151122 1.2137053813481833 0.4518010385723936 0.09101559822883122 530.7943464107877 1417251.2127133093 0.027183848476551305 0.05784673298545768 5.361235742200522e-06 5.270735095724541 0.20775911453307105 TAFYNEDDS(ph)EEEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TAFYNEDDSEEEQR 14 0 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 TAFYNEDDS(1)EEEQR;TAFYNEDDS(1)EEEQR;TAFYNEDDS(1)EEEQR 226.7 1.6823e-20 36748400.0 38441.0 38106.4 51997.0 42700.0 49275.0 40320.0 46291.4 37105.0 42218.0 41611.2 True False 44948.30205564175 41889.35155557585 53236.8056797206 40307.657435267836 39619.9174735472 38205.54822069663 41906.34347128689 36131.03306599722 42835.35838139091 49154.981165922036 0.9144200849944242 0.8521893521671559 1.0830398957944958 0.8200116545505294 0.8060203978069008 0.7772467268725884 0.8525350326110906 0.7350431677318187 0.8714347430385679 1.0 15.585050000372597 TAFYNEDDS(ph)EEEQR ddPTM_PC-9_Lapatinib_30min_R1 4 TAFYNEDDSEEEQR 14 0 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 TAFYNEDDS(1)EEEQR;TAFYNEDDS(1)EEEQR;TAFYNEDDS(1)EEEQR;TAFYNEDDS(1)EEEQR 270.79 5.502799999999999e-57 125226000.0 78339.0 101294.0 93201.0 73176.0 79532.0 91671.0 86828.0 87085.0 98440.0 72286.4 True False 77221.87149438703 101059.45996648486 85538.37354626395 78557.6071479799 74854.0841259281 87750.44502553824 91323.52898733305 91131.28701942285 87352.65058084452 84781.00792442633 0.9108392714937111 1.1920058800972162 1.0089331990781796 0.9265943997505436 0.8829109957344801 1.0350247912098292 1.0771696541840916 1.0749021420063458 1.0303327681443768 1.0 16.37145349761653 -6.983687094446364 24.993633988968025 1.052450768032359 0.990466029534746 0.11189009629131597 0.08203829301691896 588.165401630056 901147.0910852967 0.03073388063108886 0.027098922708354786 1.0382762157515235e-07 6.983687094446364 -0.06198473849761288 TAGTSFMMT(ph)PYVVTR ddPTM_PC-9_AZD4547_30min_R2 1 TAGTSFMMTPYVVTR 15 0 P45983-2;P45983-5;P45983-3;D6RJF9;A0A286YEX7;A0A286YFC0;A0A1P0B7D2;A0A286YFJ6;A0A286YFJ4;A0A286YES9;A0A286YEN5;A0A286YES0;A0A286YF85;A0A286YF97;A0A286YFA6;A0A286YF62;F8W9R5;A0A1W2PRF2;A0A286YFI3;A0A286YEW9;A0A286YEQ7;A0A1W2PPZ3;A0A286YFD7;A0A286YF35;A0A286YF83;A0A286YF02;A0A286YEY0;A0A286YEV3;A0A286YFN2;A0A286YFB6;A0A286YFM6;A0A286YF19;A0A286YEV8;A0A286YEQ0;P53779-3;P45983-4;P45983;P53779-2;P53779;D6RCB1;A0A286YFE2 P45983-2 MAPK8;MAPK10 Mitogen-activated protein kinase 8;Mitogen-activated protein kinase 10 1 T(0.002)AGT(0.03)S(0.13)FMMT(0.826)PY(0.012)VVTR 65.241 0.030465 4650600.0 12972.0 10540.0 13619.0 24557.0 18587.0 16291.0 16396.0 20780.0 11965.0 21851.0 True False 17096.826165638275 13946.848879066201 13438.403161503476 18895.763051867918 16006.515884973996 15272.321194670218 17855.212236739273 17568.928476895915 12597.445472968375 21086.003140926765 0.8108139817381645 0.661426861499235 0.6373139125366192 0.8961282479936792 0.7591062079425681 0.7242871535491469 0.8467803081221824 0.8332033510322114 0.5974316416807048 1.0 14.363998037259206 -11.479852877676112 2.527760635450519 1.190986856471168 0.7546388538810143 0.3917626807977326 0.09270719171354538 57034828.17624093 28435942.42882258 63942225.336730905 0.023462680157669183 3.3124331501659883e-12 11.479852877676112 -0.4363480025901538 TAGTSFMMT(ph)PYVVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TAGTSFMMTPYVVTR 15 0 P45983-2;P45983-5;P45983-3;D6RJF9;A0A286YEX7;A0A286YFC0;A0A1P0B7D2;A0A286YFJ6;A0A286YFJ4;A0A286YES9;A0A286YEN5;A0A286YES0;A0A286YF85;A0A286YF97;A0A286YFA6;A0A286YF62;F8W9R5;A0A1W2PRF2;A0A286YFI3;A0A286YEW9;A0A286YEQ7;A0A1W2PPZ3;A0A286YFD7;A0A286YF35;A0A286YF83;A0A286YF02;A0A286YEY0;A0A286YEV3;A0A286YFN2;A0A286YFB6;A0A286YFM6;A0A286YF19;A0A286YEV8;A0A286YEQ0;P53779-3;P45983-4;P45983;P53779-2;P53779;D6RCB1;A0A286YFE2 P45983-2 MAPK8;MAPK10 Mitogen-activated protein kinase 8;Mitogen-activated protein kinase 10 1 TAGT(0.004)S(0.016)FMMT(0.98)PYVVTR 86.539 0.0048352 5853600.0 22811.0 17520.0 22704.0 25061.0 27346.0 30813.0 37889.0 36045.0 33584.0 20272.0 True False 26672.45176221339 19259.269814353724 23245.349465399497 23656.91341885825 21987.74760490353 29197.11203681361 34299.879627394905 35098.85694283438 34075.10246531415 23947.153126936293 1.1138047024141513 0.8042404753611596 0.9706936495617347 0.9878799911396744 0.9181779349033025 1.2192310243329947 1.4323155427111556 1.4656797305628118 1.4229291592488176 1.0 14.547566535979607 -6.9153953581621055 3.5292569255753024 1.3664118046751967 0.9524856554644685 0.6006050148950393 0.14292322934914983 0.14212290446970594 3.5031799093746456 0.050973936613502385 0.043958533001592505 1.2150793546076608e-07 6.9153953581621055 -0.41392614921072823 TAGTSFMMT(ph)PYVVTR ddPTM_PC-9_Lapatinib_30min_R1 1 TAGTSFMMTPYVVTR 15 0 P45983-2;P45983-5;P45983-3;D6RJF9;A0A286YEX7;A0A286YFC0;A0A1P0B7D2;A0A286YFJ6;A0A286YFJ4;A0A286YES9;A0A286YEN5;A0A286YES0;A0A286YF85;A0A286YF97;A0A286YFA6;A0A286YF62;F8W9R5;A0A1W2PRF2;A0A286YFI3;A0A286YEW9;A0A286YEQ7;A0A1W2PPZ3;A0A286YFD7;A0A286YF35;A0A286YF83;A0A286YF02;A0A286YEY0;A0A286YEV3;A0A286YFN2;A0A286YFB6;A0A286YFM6;A0A286YF19;A0A286YEV8;A0A286YEQ0;P53779-3;P45983-4;P45983;P53779-2;P53779;D6RCB1;A0A286YFE2 P45983-2 MAPK8;MAPK10 Mitogen-activated protein kinase 8;Mitogen-activated protein kinase 10 1 TAGTS(0.001)FMMT(0.983)PY(0.016)VVTR 98.75399999999999 0.0019489000000000002 3879100.0 32869.0 28802.0 34402.0 27369.0 35714.0 36980.0 41894.0 33781.0 39711.0 27927.0 True False 32400.28203256363 28735.310738589607 31573.60035556028 29381.807560307556 33613.372736425554 35398.45160459037 44063.06633108366 35350.588583603545 35238.32900463145 32754.144739611584 0.9891963991164756 0.8773030395703859 0.9639574046754578 0.8970409025754333 1.0262326494446625 1.0807319771589354 1.3452668870268352 1.0792706958045504 1.0758433561544225 1.0 14.999389857709025 -6.625274779180714 2.574750728912139 1.138015879793988 0.9315662406275683 0.47874238220209786 0.08968570469802946 0.22722540146943673 3.0599478648340708 0.03248940634831428 0.03263434589543661 2.3698738062642248e-07 6.625274779180714 -0.20644963916641978 TAGTSFMMTPY(ph)VVTR ddPTM_PC-9_AZD4547_30min_R2 1 TAGTSFMMTPYVVTR 15 0 P45983-2;P45983-5;P45983-3;D6RJF9;A0A286YEX7;A0A286YFC0;A0A1P0B7D2;A0A286YFJ6;A0A286YFJ4;A0A286YES9;A0A286YEN5;A0A286YES0;A0A286YF85;A0A286YF97;A0A286YFA6;A0A286YF62;F8W9R5;A0A1W2PRF2;A0A286YFI3;A0A286YEW9;A0A286YEQ7;A0A1W2PPZ3;A0A286YFD7;A0A286YF35;A0A286YF83;A0A286YF02;A0A286YEY0;A0A286YEV3;A0A286YFN2;A0A286YFB6;A0A286YFM6;A0A286YF19;A0A286YEV8;A0A286YEQ0;P53779-3;P45983-4;P45983;P53779-2;P53779;D6RCB1;A0A286YFE2 P45983-2 MAPK8;MAPK10 Mitogen-activated protein kinase 8;Mitogen-activated protein kinase 10 1 TAGTS(0.001)FMMT(0.214)PY(0.76)VVT(0.025)R 61.48 0.018561 4217300.0 7512.0 6339.8 6650.3 12001.0 12496.0 8957.4 6898.6 15071.0 10638.0 9856.6 True False 9900.659740693396 8389.016368453877 6562.11267677117 9234.3548636017 10761.146096660843 8397.292361987542 7512.5620356409845 12742.123247126963 11200.302962092572 9511.523434115552 1.040912090399957 0.8819845134759894 0.6899118445352768 0.9708597079706796 1.131379864771525 0.8828546152626265 0.7898379358132291 1.3396511437299334 1.177550898094807 1.0 13.21546071668614 -7.758568046359685 24.999800683521723 1.193950769112584 0.9123158545906583 0.4207467974731157 0.13903969725454182 68.52343069061287 596629.8498372011 0.07095404715806093 0.03863596115634091 1.7435401537748193e-08 7.758568046359685 -0.2816349145219256 TAGTSFMMTPY(ph)VVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TAGTSFMMTPYVVTR 15 0 P45983-2;P45983-5;P45983-3;D6RJF9;A0A286YEX7;A0A286YFC0;A0A1P0B7D2;A0A286YFJ6;A0A286YFJ4;A0A286YES9;A0A286YEN5;A0A286YES0;A0A286YF85;A0A286YF97;A0A286YFA6;A0A286YF62;F8W9R5;A0A1W2PRF2;A0A286YFI3;A0A286YEW9;A0A286YEQ7;A0A1W2PPZ3;A0A286YFD7;A0A286YF35;A0A286YF83;A0A286YF02;A0A286YEY0;A0A286YEV3;A0A286YFN2;A0A286YFB6;A0A286YFM6;A0A286YF19;A0A286YEV8;A0A286YEQ0;P53779-3;P45983-4;P45983;P53779-2;P53779;D6RCB1;A0A286YFE2 P45983-2 MAPK8;MAPK10 Mitogen-activated protein kinase 8;Mitogen-activated protein kinase 10 1 TAGTSFMMT(0.227)PY(0.772)VVTR 104.07 0.0021550000000000002 0.0 6849.8 7565.3 7936.6 7710.1 11746.0 9329.8 9017.7 14751.0 10342.0 6470.7 True False 8009.335850283158 8316.332986674102 8125.838643723111 7278.128093481463 9444.45561936652 8840.52886382577 8163.478173505744 14363.801879976414 10493.232184858236 7643.786687966983 1.0478230459899713 1.087986010881996 1.0630645484279388 0.9521626375234742 1.2355728914092003 1.1565640466841813 1.0679887478227081 1.879147399886005 1.3727793060181694 1.0 12.900071802837974 -7.657159051180253 23.489267688453722 1.470555213292706 1.0895524402760326 0.3306969758414884 0.2110782752055924 6.110680052991275 1356.9287825081087 0.09344330919935878 0.05394944488104081 2.2021198354836676e-08 7.657159051180253 -0.3810027730166734 TAGTSFMMTPY(ph)VVTR ddPTM_PC-9_Lapatinib_30min_R1 1 TAGTSFMMTPYVVTR 15 0 P45983-2;P45983-5;P45983-3;D6RJF9;A0A286YEX7;A0A286YFC0;A0A1P0B7D2;A0A286YFJ6;A0A286YFJ4;A0A286YES9;A0A286YEN5;A0A286YES0;A0A286YF85;A0A286YF97;A0A286YFA6;A0A286YF62;F8W9R5;A0A1W2PRF2;A0A286YFI3;A0A286YEW9;A0A286YEQ7;A0A1W2PPZ3;A0A286YFD7;A0A286YF35;A0A286YF83;A0A286YF02;A0A286YEY0;A0A286YEV3;A0A286YFN2;A0A286YFB6;A0A286YFM6;A0A286YF19;A0A286YEV8;A0A286YEQ0;P53779-3;P45983-4;P45983;P53779-2;P53779;D6RCB1;A0A286YFE2 P45983-2 MAPK8;MAPK10 Mitogen-activated protein kinase 8;Mitogen-activated protein kinase 10 1 TAGTS(0.001)FMMT(0.087)PY(0.91)VVT(0.001)R 77.387 0.022276 0.0 8755.9 7534.3 9881.2 9338.5 11696.0 12278.0 11150.0 9847.5 10403.0 7767.7 True False 8631.039260364589 7516.854791256011 9068.805878535031 10025.284442322774 11008.06427522073 11752.898561415925 11727.292442631002 10305.050800066198 9231.304591553495 9110.336595190356 0.9473897226718491 0.8250907870104826 0.9954413630911013 1.1004296424805478 1.2083048919435364 1.2900619465169556 1.287251279916729 1.1311383166135234 1.0132781039535907 1.0 13.153288642228503 -5.7013909554480176 2.2660682317054097 1.1733532899987742 0.8873081562200218 0.5400477758216808 0.09760858010014754 0.21732544406218554 2.266521663510497 0.030240808498849234 0.06028516106988084 1.988882124904278e-06 5.7013909554480176 -0.2860451337787524 TAHNSEAADLEES(ph)FNEHELEPSSPK ddPTM_PC-9_AZD4547_30min_R2 1 TAHNSEAADLEESFNEHELEPSSPK 25 0 A0A0D9SGE8;Q5JRC6;Q8IWS0-2 A0A0D9SGE8 PHF6 PHD finger protein 6 1 TAHNSEAADLEES(0.958)FNEHELEPS(0.013)S(0.029)PK 59.614 0.003175 3195100.0 8990.4 9373.6 20310.0 52888.0 32310.0 28694.0 9898.1 25390.0 16632.0 24171.0 True False 11849.160188063086 12403.43288926137 20040.676129681757 40695.4887114546 27824.31421119651 26899.759643967056 10779.011724839525 21466.55890415723 17511.13356509904 23324.7806470798 0.5080073578118116 0.5317706124200678 0.859201054574153 1.7447318938259584 1.1929078619086624 1.1532695655740213 0.46212703510200126 0.920332723765391 0.7507523363265322 1.0 14.509575893172755 -12.190517376712474 2.052848023883051 2.909920282902021 0.9186365584548413 0.004515783807104268 0.3702855699255191 50790165.246722296 3168136.4610762503 449667910.5062033 0.10705777585918477 6.448855166059084e-13 12.190517376712474 -1.9912837244471797 TAHNSEAADLEESFNEHELEPS(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 1 TAHNSEAADLEESFNEHELEPSSPK 25 0 A0A0D9SGE8;Q5JRC6;Q8IWS0-2 A0A0D9SGE8 PHF6 PHD finger protein 6 1 TAHNSEAADLEESFNEHELEPS(0.5)S(0.5)PK 73.616 0.001819 0.0 1074.5 996.36 3877.8 8024.5 4616.5 2959.2 1850.6 4405.5 3689.1 3819.3 True False 1416.1686490115897 1318.4138851182536 3826.3778382904916 6174.575502289126 3975.5786615904926 2774.160756200851 2015.2998149127645 3724.7312033188146 3884.098294553084 3685.5874695044427 0.38424502490562384 0.35772150193888225 1.038200251642645 1.6753300670189626 1.078682488066154 0.7527051736405702 0.5468055857004902 1.0106207583291016 1.0538613794113352 1.0 11.847678882758489 -5.261116120661445 24.493434752790506 1.0190271994020639 0.3709831899555501 0.47947748026479764 0.2702921336518521 19.773900300151755 1498046.8678578627 0.07917682161581212 0.1848685923138506 5.481303874814428e-06 5.261116120661445 -0.6480440094465139 TAHNSEAADLEESFNEHELEPS(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TAHNSEAADLEESFNEHELEPSSPK 25 0 A0A0D9SGE8;Q5JRC6;Q8IWS0-2 A0A0D9SGE8 PHF6 PHD finger protein 6 1 TAHNSEAADLEES(0.314)FNEHELEPS(0.368)S(0.318)PK 76.73100000000001 0.00012312 3845900.0 19462.0 19552.0 34417.0 39758.0 56821.0 48236.0 40487.0 42592.0 41410.0 30258.0 True False 22756.532207978453 21492.993345333576 35237.63180719937 37530.48815717512 45687.33294296143 45706.419245375066 36651.77825950373 41474.00512995427 42015.54290997675 35743.53587780379 0.6366614731619186 0.6013113369312858 0.9858462779862083 1.0499937187378543 1.2781984720021107 1.2787324511383351 1.0254099758010775 1.1603218347435238 1.175472484132936 1.0 15.125394737517277 -5.42086198134736 2.010018231725613 1.1559608781510171 0.5932613594357138 0.8311823902258747 0.09207693150451098 0.12981816078581515 0.9942333149312593 0.026957853904767987 0.0809417177304302 3.79435550315924e-06 5.42086198134736 -0.5626995187153033 TAHNSEAADLEESFNEHELEPSS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 TAHNSEAADLEESFNEHELEPSSPK 25 0 A0A0D9SGE8;Q5JRC6;Q8IWS0-2 A0A0D9SGE8 PHF6 PHD finger protein 6 1 TAHNSEAADLEES(0.058)FNEHELEPS(0.284)S(0.658)PK 59.99100000000001 0.0029771999999999997 2738900.0 6185.4 8035.5 18931.0 34733.0 19704.0 20562.0 11665.0 21228.0 12177.0 16859.0 True False 8152.22853568756 10632.81823223306 18679.962570704338 26725.843469500694 16968.439715797478 19276.254889497814 12703.162401900685 17947.70037091176 12820.6513601618 16268.771541480228 0.501096749370532 0.6535722875647206 1.1482097786594603 1.6427696093314874 1.043006822766754 1.1848623505683544 0.7808310768586082 1.103199484063735 0.7880528242389532 1.0 13.98981769645259 -5.175549072371226 4.298471555025062 1.100818420021689 0.5424161056250031 0.44606180160489883 0.22834449454207456 0.2075483015988935 6.860481833282394 0.062397507223326286 0.18250149292655857 6.674994737277317e-06 5.175549072371226 -0.558402314396686 TAHNSEADLEESFNEHELEPS(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 1 TAHNSEADLEESFNEHELEPSSPK 24 0 Q8IWS0-5;Q8IWS0 Q8IWS0-5 PHF6 PHD finger protein 6 1 T(0.003)AHNS(0.011)EADLEES(0.027)FNEHELEPS(0.751)S(0.209)PK 59.547 0.0027132 12423000.0 5048.5 7148.8 8030.9 15993.0 12275.0 10625.0 6718.2 11315.0 8659.7 11342.0 True False 6653.817984676597 9459.509797596626 7924.405018703159 12306.06093938688 10570.828131923161 9960.61707036837 7316.106785122084 9566.526742833363 9117.434062872064 10944.920032236125 0.6079366468717062 0.8642831349827579 0.7240258490115388 1.1243628005633464 0.9658204994452998 0.9100675967509417 0.6684477148826963 0.8740609081342784 0.8330288422408243 1.0 13.417973793226112 -4.2819400147118065 1.4314866584751547 0.8882537745107504 1.5305294614643977e-09 0.3134050929709076 0.12367542735216341 5.905952879486889 4.138888282961006 0.03665632426746747 10.700274425833754 5.224683479867265e-05 4.2819400147118065 -0.8882537729802209 TAHNSEADLEESFNEHELEPSS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 TAHNSEADLEESFNEHELEPSSPK 24 0 Q8IWS0-5;Q8IWS0 Q8IWS0-5 PHF6 PHD finger protein 6 1 TAHNSEADLEES(0.035)FNEHELEPS(0.294)S(0.671)PK;TAHNSEADLEES(0.013)FNEHELEPS(0.217)S(0.77)PK 52.427 0.014986000000000001 28738300.0 8830.0 10084.0 21708.2 51486.0 32321.0 25465.4 14802.6 31852.8 17889.6 23579.1 True False 11637.756324590355 13343.45579663221 21420.335084114093 39616.698150770535 27833.78705107035 23873.044512353743 16120.002723564085 26930.681664526954 18835.207733657757 22753.602885919467 0.5114687279609731 0.5864326569964661 0.9414041016497464 1.741117586933294 1.2232694395969543 1.0491984338500966 0.7084593505646338 1.1835787852829398 0.8277901230891871 1.0 14.473807384381793 -5.325756888806386 4.001112654132252 1.1122574368638318 0.5403534118119456 0.40895599334609456 0.2615986422360362 0.21663971969780965 6.877069385275799 0.0745652364739718 0.1749204157840619 4.72327368676636e-06 5.325756888806386 -0.5719040250518862 TAHNSEADLEESFNEHELEPSS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TAHNSEADLEESFNEHELEPSSPK 24 0 Q8IWS0-5;Q8IWS0 Q8IWS0-5 PHF6 PHD finger protein 6 1 TAHNSEADLEES(0.014)FNEHELEPS(0.055)S(0.932)PK 64.423 0.0012286 11492000.0 22558.0 22292.0 48950.0 77111.0 84530.0 72073.0 45004.0 46917.0 54683.0 42055.0 True False 26376.62385919114 24505.002437304414 50117.15364390879 72790.72066723501 67966.95330368234 68293.36500273485 40740.895319255724 45685.478462670566 55482.63542492772 49679.23859280317 0.5309385692358862 0.49326445274574626 1.0088148502978276 1.4652140960505764 1.368115841323068 1.374686225819657 0.8200788996222195 0.9196090712487054 1.1168173465719191 1.0 15.60035544185976 -5.335005122124376 4.058363708029072 1.157555869310888 0.5065469234874853 0.6189532170975112 0.19721707483899778 0.15147866530737106 4.761868961359253 0.05937371904593964 0.13731591946430508 4.6237556805082255e-06 5.335005122124376 -0.6510089458234027 TAHNSEADLEESFNEHELEPSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 TAHNSEADLEESFNEHELEPSSPK 24 0 Q8IWS0-5;Q8IWS0 Q8IWS0-5 PHF6 PHD finger protein 6 1 TAHNSEADLEES(0.04)FNEHELEPS(0.108)S(0.851)PK 93.529 6.39e-06 14332000.0 33370.0 18249.0 55977.0 23239.0 38663.0 51735.0 27766.0 31763.0 51543.0 22668.0 True False 32894.13768069149 18206.745561715215 51374.78713746868 24948.07358303144 36388.918354382615 49522.41465017531 29203.587619918588 33238.82493653238 45737.68456814784 26586.133596788593 1.2372666962248644 0.6848211115554784 1.9323903173221988 0.9383866778599571 1.3687179529850149 1.8627159330966896 1.0984518494801427 1.2502316222674583 1.7203586373940665 1.0 14.698386361847518 -5.237054803038882 24.997088598626345 1.394009474166928 0.9610439765837714 0.19646639586813253 0.3521567082997257 1223.9858339101231 1254726.6826882341 0.08492049801587843 0.22444931059650414 5.7935558370898775e-06 5.237054803038882 -0.4329654975831566 TAIT(ph)TPNFK ddPTM_PC-9_AZD4547_30min_R2 2 TAITTPNFK 9 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6;Q9BXS6-7;H0YMD2 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 TAIT(0.934)T(0.066)PNFK;T(0.008)AIT(0.592)T(0.399)PNFK 169.99 0.004645300000000001 23163000.0 149656.0 183984.0 173802.0 237740.0 198662.0 208690.0 154297.0 201148.0 171899.0 188514.0 True False 197243.49496182293 243453.22999678503 171497.2719197907 182932.71604638512 171081.21045573306 195640.58130966336 168029.1340871042 170065.19852120618 180985.23020123606 181914.18223919577 1.084266726947495 1.3382861467979041 0.9427372281194215 1.0055989796653133 0.9404500976772738 1.0754553542857863 0.9236725362411032 0.9348649809919187 0.9948934600561365 1.0 17.472898495977986 -5.276076757889808 24.99778270055191 0.9761807013073183 1.2112764408878598 0.6332648625336488 0.07124647865251023 390.6808690123822 667206.5123302642 0.01731452779793793 0.036298496910551016 5.2956983861372395e-06 5.276076757889808 0.23509573958054153 TAIT(ph)TPNFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TAITTPNFK 9 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6;Q9BXS6-7;H0YMD2 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 T(0.001)AIT(0.624)T(0.375)PNFK;TAIT(0.929)T(0.071)PNFK 153.1 0.00016331 25991000.0 166289.0 186388.0 152259.0 185508.0 183083.0 140764.0 162780.0 116101.0 115133.0 102844.0 True False 194438.44334254047 204891.36884462152 155889.4320054729 175114.5881850505 147209.200422312 133382.08803914022 147360.29997485635 113053.47176917776 116816.60231476332 121488.80308734407 1.600463897917814 1.68650413567179 1.2831588429873375 1.4414051643850034 1.2117100233218718 1.097896140628248 1.21295375565526 0.9305670061453997 0.9615421285431409 1.0 16.89046382962806 -5.737535250327346 0.4407473492430138 0.9464395951316108 1.8548276601150109 0.8541870778877563 0.0954079651512009 0.8057352514377351 0.22246225285822827 0.0791664233384015 0.35465989152264027 1.8300575602234094e-06 5.737535250327346 0.9083880649834001 TAIT(ph)TPNFK ddPTM_PC-9_Lapatinib_30min_R1 3 TAITTPNFK 9 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6;Q9BXS6-7;H0YMD2 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 TAIT(0.5)T(0.5)PNFK;T(0.001)AIT(0.916)T(0.082)PNFK;T(0.002)AIT(0.867)T(0.13)PNFK 160.77 0.00035422 39377000.0 463160.0 486820.0 504790.0 370751.0 378820.0 408760.0 370983.0 344999.0 380957.0 264905.0 True False 456555.2534668573 485692.79820013273 463288.1147457505 398017.265329079 356538.55238877586 391278.2876660994 390190.6845062404 361028.9130207707 338049.611004945 310693.4762862752 1.4694716442844908 1.5632539311916929 1.4911420744440527 1.281060903133811 1.1475572536973988 1.2593707867415045 1.255870220289775 1.1620099570037836 1.0880486292974612 1.0 18.245132423562325 -4.264816007758468 0.22045277467820698 0.9865208431299063 2.2047949019488646 0.8381522541553587 0.07057573685878074 6.424727192566429 0.23054387869949983 0.13753498577603654 2.220331034519643 5.434805324884701e-05 4.264816007758468 1.2182740588189582 TAITT(ph)ASIRR ddPTM_PC-9_AZD4547_30min_R2 1 TAITTASIRR 10 1 Q8IXS8 Q8IXS8 FAM126B Protein FAM126B 1 TAIT(0.001)T(0.897)AS(0.102)IRR 95.40100000000001 0.005035100000000001 3423900.0 18672.0 13385.0 21961.0 23100.0 21508.0 17851.0 20600.0 23271.0 15463.0 21213.0 True False 24609.30759827306 17711.439492058926 21669.782790937505 17774.651891442307 18521.98545510414 16734.774148060776 22433.360092512146 19675.001664381365 16280.342611659838 20470.339326734684 1.2021934373180028 0.8652245187224338 1.0585942150278047 0.8683125183092714 0.9048206363103148 0.8175132752296304 1.095895858610107 0.9611468256750101 0.7953137635777916 1.0 14.321247396954245 -4.752724261102041 24.888515086802848 0.9314608792049471 1.202193981510256 0.4277841469178687 0.0945438555305651 309.14485962665697 882781.587199514 0.023009753880710054 0.2655418737731152 1.7671594558106725e-05 4.752724261102041 0.2707331023053089 TAITT(ph)PNFK ddPTM_PC-9_AZD4547_30min_R2 1 TAITTPNFK 9 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6;Q9BXS6-7;H0YMD2 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 TAIT(0.041)T(0.958)PNFK 115.7 0.004799800000000001 18499000.0 114870.0 110060.0 116750.0 164010.0 151860.0 148040.0 121330.0 125410.0 110920.0 148160.0 True False 151396.27055557133 145634.74265939533 115201.81871690524 126200.02842924053 130776.86029440758 138783.03539739575 132128.1349526452 106030.76613510647 116783.00475233188 142972.96349639428 1.0589153840921084 1.0186173602190751 0.8057594659833052 0.8826845673687336 0.9146964369784901 0.970694262771547 0.9241476970292878 0.7416141034090024 0.8168188019357737 1.0 17.125382830409364 -5.12813314463537 5.5489239754426825 0.8790219114556748 1.048894023171019 0.4207265688487719 0.07399249889914489 0.21061547169634548 8.439816812120577 0.01998777614228626 0.05588026793058793 7.445036913162534e-06 5.12813314463537 0.16987211171534433 TAITT(ph)PNFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TAITTPNFK 9 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6;Q9BXS6-7;H0YMD2 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 TAIT(0.016)T(0.984)PNFK 105.2 0.0064854 10067000.0 65024.0 59821.0 59522.0 67203.0 68899.0 55262.0 63998.0 49302.0 41534.0 44942.0 True False 76031.27891745922 65759.63353678392 60941.230218442055 63437.8337850657 55398.735545609896 52363.96343680896 57935.6461346042 48007.874739786945 42141.356175391804 53089.62883932376 1.4321305418722847 1.238653103712705 1.1478933183518996 1.1949195195366853 1.0434944970754019 0.9863313152045 1.0912799241815563 0.9042797207168882 0.7937775625241795 1.0 15.696142434864196 -4.083854574605163 0.33560566549526644 0.8982930223145668 2.0783877979305267 0.8036247469575334 0.0762810294400597 4.819894993209932 0.3040863039935343 0.07587479958695999 2.524800053432963 8.244141274521644e-05 4.083854574605163 1.1800947756159599 TAITT(ph)PNFK ddPTM_PC-9_Lapatinib_30min_R1 1 TAITTPNFK 9 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6;Q9BXS6-7;H0YMD2 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 TAIT(0.038)T(0.962)PNFK 115.7 0.004799800000000001 11952000.0 92346.0 93367.0 92091.0 67833.0 68899.0 78343.0 76927.0 63795.0 73363.0 55417.0 True False 91029.12910581747 93150.8144479513 84519.63346154024 72821.66510425438 64846.496280645806 74992.45251645283 80909.90365329817 66759.14859509743 65100.08639336153 64995.75461148907 1.400539614470859 1.4331830594899402 1.3003869863001791 1.1204064871551156 0.9977035679986261 1.1538053979789733 1.2448490541718553 1.0271309102286605 1.001605209178601 1.0 15.988057866906285 -5.648099954578181 2.5839193280341832 1.0825921250518817 1.4142528038095394 0.7794555447399583 0.07500014910406032 0.13542816444311145 1.8208568837110377 0.023274603170121814 0.04652748027607927 2.248537036660711e-06 5.648099954578181 0.3316606787576577 TAITT(ph)PNFKK ddPTM_PC-9_Lapatinib_30min_R1 1 TAITTPNFKK 10 1 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6;Q9BXS6-7;H0YMD2 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 TAIT(0.026)T(0.974)PNFKK 88.056 0.034886 3489300.0 43230.0 32563.0 35217.0 28525.0 24337.0 26472.0 23660.0 20152.0 33294.0 15897.0 True False 42613.532272588935 32487.60237416475 32321.59420155126 30622.8236566105 22905.54550838296 25339.854269245985 24884.999030730887 21088.33548849292 29544.07911863714 18644.775268578993 2.2855481848796084 1.742450735188764 1.7335469983390495 1.64243458102804 1.2285235503473408 1.3590860658937434 1.3346902106494252 1.131058711339467 1.5845768422012647 1.0 14.186483787502485 -1.5228787452819323 0.35672792477290877 1.2053834980493012 13.949142531125185 0.7922737475963639 0.16208238701530256 26.96292233485102 0.37746895839929884 0.12892484676565344 232.59719375196798 0.029999999999889837 1.5228787452819323 12.743759033075884 up TAITTAS(ph)IRR ddPTM_PC-9_AZD4547_30min_R2 1 TAITTASIRR 10 1 Q8IXS8 Q8IXS8 FAM126B Protein FAM126B 1 TAITT(0.007)AS(0.993)IRR 104.59 0.0011837999999999998 2848800.0 17746.0 14830.0 21189.0 32987.0 27891.0 23931.0 28124.0 26773.0 25416.0 28019.0 True False 23388.85886026959 19623.507483543795 20908.020015353348 25382.35679406959 24018.81608370419 22434.590786916266 30626.98151659278 22635.84803233565 26759.43787220762 27038.063338319855 0.8650345465801758 0.7257734120229041 0.7732809762939394 0.9387638632422425 0.8883334498911164 0.8297410397408423 1.1327357708045054 0.8371845183251294 0.9896950657069676 1.0 14.722704198615437 -6.195445065172557 0.8494616979398916 0.9682074313022618 0.7766376476895525 0.38195192139243817 0.0897495374657288 0.7002925454156591 1.0713795126740124 0.04527255642584602 0.08200875596208515 6.37609728537114e-07 6.195445065172557 -0.19156978361270938 TAITTAS(ph)IRR ddPTM_PC-9_Lapatinib_30min_R1 2 TAITTASIRR 10 1 Q8IXS8 Q8IXS8 FAM126B Protein FAM126B 1 TAITT(0.055)AS(0.945)IRR;TAITT(0.019)AS(0.981)IRR 92.792 0.004220000000000001 2107300.0 59459.0 43812.0 45774.0 49480.0 38253.0 38072.0 29813.0 28556.0 43148.0 26487.0 True False 58611.10375655482 43710.55600580127 42010.63841274975 53118.924260441294 36003.03374829163 36443.749310166706 31356.571263870646 29882.816008803264 38288.21787141695 31065.242658290976 1.8867099929416502 1.4070566416172963 1.352335755907497 1.7099149955058996 1.1589490590598304 1.1731358325778365 1.009377960081761 0.9619373116606853 1.2325098597354185 1.0 14.9230137031207 -6.37951423834193 4.757784698988411 1.0782872890746826 1.5577829120639228 0.700851351357875 0.15988980197069305 0.13794428918018764 4.801313494788864 0.05080927003762359 0.057779207804892686 4.1733591588558005e-07 6.37951423834193 0.4794956229892402 TALAT(ph)SPITVGDLGIVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TALATSPITVGDLGIVR 17 0 P13994 P13994 CCDC130 Coiled-coil domain-containing protein 130 1 TALAT(0.912)S(0.087)PIT(0.001)VGDLGIVR 135.61 0.00010271 1846300.0 9770.3 8959.3 9475.1 10753.0 14816.0 9922.7 13475.0 9400.8 8668.5 9661.9 True False 11424.218817778854 9848.720094049055 9701.022318516852 10150.544271696366 11912.91115754591 9402.336144084977 12198.550449448296 9154.038960970935 8795.26041330919 11413.525986441684 1.000936856090736 0.8628989942063927 0.8499584028669893 0.8893434232115794 1.0437538033117422 0.8237889110914688 1.0687801879926637 0.8020342680995486 0.7705997624009641 1.0 13.478456932553769 TALATS(ph)PITVGDLGIVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TALATSPITVGDLGIVR 17 0 P13994 P13994 CCDC130 Coiled-coil domain-containing protein 130 1 TALAT(0.463)S(0.527)PIT(0.01)VGDLGIVR 163.91 2.9996999999999998e-05 1937000.0 8727.5 9361.4 9259.4 11045.0 14950.0 8918.0 8355.8 8935.3 9460.3 9739.5 True False 10204.893374017684 10290.737924662733 9480.179212470051 10426.184458373138 12020.654819472968 8450.32438075824 7564.278133246749 8700.75784273292 9598.638990370755 11505.194252160418 0.8869814059942042 0.894442779419423 0.8239912342801067 0.9062154214749859 1.044802421933533 0.7344790705442855 0.6574663554095445 0.7562460617385155 0.834287434005588 1.0 13.48999772158713 -6.796472045527609 24.999990165111495 0.7725717712574923 0.9052196420010655 0.23554047339355866 0.09850407187782172 229.7952362190972 163984.81629370037 0.03449391896252598 0.030422028156258697 1.5978203735337192e-07 6.796472045527609 0.1326478707435732 TALATS(ph)PITVGDLGIVR ddPTM_PC-9_Lapatinib_30min_R1 1 TALATSPITVGDLGIVR 17 0 P13994 P13994 CCDC130 Coiled-coil domain-containing protein 130 1 T(0.002)ALAT(0.034)S(0.964)PIT(0.001)VGDLGIVR 173.19 1.0468e-24 0.0 6232.3 8544.4 8453.0 5281.5 10145.0 9369.0 8592.9 8250.1 10164.0 7935.9 True False 6143.426259136152 8524.61596676637 7758.026969523609 5669.919128567519 9548.291045837406 8968.30971020571 9037.798316617393 8633.429764470791 9019.223288335072 9307.609741077935 0.660043387081748 0.9158759556864613 0.8335144237176767 0.609170268876236 1.0258585513848153 0.9635459542985814 0.9710117385702406 0.9275667979898494 0.9690160566713378 1.0 13.184195005889352 -6.282586909634388 24.96109157743231 0.9716560972757857 0.7718001597149344 0.6270781988428014 0.08322432282624495 571.2729645250716 674289.5800898814 0.02584914125122848 0.029339595965181903 5.216906947049751e-07 6.282586909634388 -0.1998559375608513 TALIHDGLAR ddPTM_PC-9_AZD4547_30min_R2 3 TALIHDGLAR 10 0 P25398 P25398 RPS12 40S ribosomal protein S12 0 ;; 123.11 0.0004049 31974000.0 93049.0 70744.0 109643.0 155234.0 129500.0 105385.0 91673.0 119167.0 101199.0 110369.0 False True 122636.64646056698 93610.61452567914 108189.06218053657 119447.19964139203 111521.16033271258 98795.25929042543 99831.71940586738 100752.4783352383 106548.17253814673 106505.01490370913 1.1514635866812695 0.8789315189553488 1.0158119059309083 1.1215171393514558 1.0470977393274723 0.9276113371726761 0.9373428987933098 0.9459881154547353 1.0004052169231337 1.0 16.700561837342157 -6.752796668205228 24.9820942839682 0.9573358563911548 1.036707024560777 0.2387740778063765 0.07133494861330753 295.70456485992304 854744.5137838193 0.024055870910195492 0.023696772519037793 1.7668648533313786e-07 6.752796668205228 0.0793711681696222 TALIHDGLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TALIHDGLAR 10 0 P25398 P25398 RPS12 40S ribosomal protein S12 0 ;;; 133.75 9.2473e-05 30469000.0 161493.0 164299.0 178254.0 215538.0 226377.0 195803.0 197319.0 190868.0 179187.0 143528.0 False True 188830.57526785863 180609.5189057365 182504.25139205993 203462.10464362413 182020.05191089198 185534.74598851835 178627.51585415154 185857.9172413623 181807.2708865005 169548.49023297738 1.1137260792377783 1.065238143126843 1.0764133089081476 1.2000230987845772 1.073557491787614 1.0942872197421174 1.0535482540050851 1.0961932895183795 1.0723025055350142 1.0 17.37133841218798 -9.359074090405008 0.41113925915350175 0.9870835769521273 1.1057107859174484 0.39159626127171776 0.03759858810127575 3.9716507276992763 0.999674487575326 0.13066621060427303 0.0265685398223486 4.374474704889515e-10 9.359074090405008 0.11862720896532108 TALIHDGLAR ddPTM_PC-9_Lapatinib_30min_R1 4 TALIHDGLAR 10 0 P25398 P25398 RPS12 40S ribosomal protein S12 0 ;;; 133.75 9.2473e-05 51844400.0 267830.0 243224.0 269484.0 245283.0 259647.0 263107.0 230736.0 234934.0 258985.0 236135.0 False True 264010.69508599327 242660.82977163838 247328.06575832277 263321.93006010173 244375.073945643 251854.52694237308 242682.38108008122 245849.89130873387 229815.3820670464 276950.62011989113 0.9532771400609387 0.8761880716013245 0.8930403031820444 0.9507901803798469 0.882377782147062 0.9093842318653989 0.8762658880309592 0.887702981861193 0.829806345866133 1.0 18.079269243278866 TALINS(ph)TGEEVAMR ddPTM_PC-9_AZD4547_30min_R2 1 TALINSTGEEVAMR 14 0 P02545;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 TALINS(0.916)T(0.084)GEEVAMR 86.539 0.0056903 4828500.0 19802.0 21230.0 29476.0 34671.0 30999.0 26412.0 26255.0 32325.0 24938.0 22573.0 True False 26098.624092812905 28092.18232472251 29085.128980723726 26678.136611610233 26695.323931689287 24760.45346471241 28591.64413732553 27329.914004603484 26256.171768063956 21782.726140686475 1.1981339674497884 1.289654111394764 1.3352382430405527 1.2247381911385258 1.2255272255306422 1.1367013157487225 1.312583372377856 1.254659946054952 1.2053666560597223 1.0 14.410896900341143 -13.377500574061575 0.3195004585467861 2.3326134123904816e-09 1.2564237022315092 0.6389792063281972 0.055055115700458616 94.98675752264319 1.6916490405581595 62.93012679140431 0.05186308637710557 4.1927544247521566e-14 13.377500574061575 1.2564236998988958 TALINS(ph)TGEEVAMR ddPTM_PC-9_Lapatinib_30min_R1 1 TALINSTGEEVAMR 14 0 P02545;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 TALINS(0.968)T(0.032)GEEVAMR 102.15 0.0013489 2406500.0 14990.0 18878.0 21311.0 17164.0 24959.0 16843.0 21905.0 20500.0 19684.0 17964.0 True False 14776.239851170663 18834.28915086087 19558.891842838933 18426.297817425508 23490.960691282 16122.664152950674 23039.13371801184 21452.50483892937 17466.9806382908 21069.053464474604 0.7013243322053119 0.89393143278212 0.928323233685746 0.874566949507003 1.1149509270025384 0.765229637873185 1.093505873762154 1.0181997437664354 0.8290349002978512 1.0 14.362837881517565 -4.100650689191545 1.0567066518913184 0.9613304541141666 2.1293992284163542e-15 0.34581433700198405 0.10451522565481405 7.124318963433546 2.3273209196245994 0.03119857236342905 10.904940173012228 7.93139009869028e-05 4.100650689191545 -0.9613304541141645 TALINST(ph)GEEVAMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TALINSTGEEVAMR 14 0 P02545;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 TALINS(0.365)T(0.635)GEEVAMR 85.176 0.026729000000000003 3839700.0 19617.0 20132.0 20346.0 20767.0 25333.0 15313.0 23109.0 20154.0 20206.0 14561.0 True False 22937.770646588917 22130.571912247113 20831.1258026347 19603.492317522414 20369.18050446212 14509.959323004152 20919.94822532842 19624.978854928137 20501.474524003628 17200.794035187417 1.3335297544790927 1.2866017619288341 1.2110560570646194 1.1396853120512827 1.1842000120920686 0.8435633432573716 1.216219913018712 1.1409344716750633 1.191891169795072 1.0 14.07018754472019 -5.487442249189198 1.2812560452594575 1.098091545723042 1.3376858201541482 0.41016538491737187 0.10296601024216592 0.5958512701360434 1.7243551154323273 0.03420224125892946 0.1342288261885085 3.255050650326026e-06 5.487442249189198 0.23959427443110615 TALINSTGEEVAMR ddPTM_PC-9_Lapatinib_30min_R1 1 TALINSTGEEVAMR 14 0 P02545;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 101.38 0.010019 0.0 7451.6 8199.0 8393.2 7118.9 7109.4 8915.5 7123.2 6608.5 9395.8 6495.2 False True 7345.33881754392 8180.01571924506 7703.143494688935 7642.447653954235 6691.239069618184 8534.204848045581 7492.004441914718 6915.555035515353 8337.5460618397 7617.886665690021 0.9642226433515189 1.0737906821437493 1.011191664137365 1.0032241209855266 0.8783589679477198 1.120285089890158 0.9834754401975734 0.9078049253032499 1.0944696905758564 1.0 12.895175109178824 -5.707137525149531 4.170150267127837 0.9937557638839808 1.0234671616614037 0.009572626501903936 0.07292034278081028 0.9669047908127133 34.292831394123596 0.019906567041229947 0.03481908971247941 1.962738651003676e-06 5.707137525149531 0.029711397777422932 TALPAQSAAT(ph)LPAR ddPTM_PC-9_AZD4547_30min_R2 1 TALPAQSAATLPAR 14 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 TALPAQS(0.003)AAT(0.997)LPAR 130.47 4.7343000000000004e-05 6099000.0 9880.3 10155.0 21974.0 25996.0 27514.0 25789.0 39011.0 32157.0 29013.0 31114.0 True False 13022.029876993205 13437.405158151547 21682.61040244345 20003.023834196305 23694.156026210512 24176.40975319808 42482.903425679164 27187.874544347567 30546.56794878657 30024.708330364538 0.4337104538605555 0.44754490236170097 0.7221589020571909 0.666218756035904 0.7891552439244907 0.8052171394034171 1.4149314277506377 0.90551669129295 1.0173810054265962 1.0 14.87386261074662 -6.187045013636739 0.7727889330194083 1.0743136853091606 0.4327304074834215 0.6901926571105678 0.1529342491862338 0.42966943938068336 0.5428402809167305 0.08688800513088725 0.16646483563713294 6.500623093691748e-07 6.187045013636739 -0.6415832778257391 TALPAQSAAT(ph)LPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TALPAQSAATLPAR 14 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 TALPAQS(0.02)AAT(0.98)LPAR 91.59200000000001 0.01095 5452600.0 10633.0 9477.5 13713.0 13948.0 20982.0 26744.0 24780.0 26525.0 24067.0 16499.0 True False 12432.95688867717 10418.363565384563 14039.969926842106 13166.538780026121 16870.727720547267 25341.49755987872 22432.659008336075 25828.746855560603 24418.934344709254 19490.13809398786 0.6379101486465288 0.5345453949655864 0.7203627731695255 0.6755487681273851 0.8656032932753511 1.3002215498768495 1.1509748622692364 1.3252213366065384 1.2528866766850555 1.0 14.25045669214657 -6.550355275464698 2.6667047992363013 1.224500227000787 0.6391490359357693 0.8777611666634542 0.0990823015775374 0.08452552358962283 1.2188820119237878 0.03386370087382401 0.0355755879376638 2.8160782902885863e-07 6.550355275464698 -0.5853511910650177 TALPAQSAAT(ph)LPAR ddPTM_PC-9_Lapatinib_30min_R1 2 TALPAQSAATLPAR 14 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 TALPAQS(0.002)AAT(0.998)LPAR;TALPAQS(0.002)AAT(0.998)LPAR 135.69 7.3354e-05 18188700.0 108707.0 102340.0 70738.0 65567.0 55539.0 57356.0 60057.0 51989.0 48003.0 32354.0 True False 107156.81824557787 102103.03801775089 64922.19469657646 70389.01590510028 52272.305213875174 54903.01758336632 63166.45759884212 54404.59873517557 42596.396646000474 37946.34579100489 2.8239034882504863 2.690721224649627 1.7108945102156883 1.8549616422297472 1.3775319895563232 1.446859149119465 1.6646255728217079 1.4337243178781152 1.1225427839773143 1.0 15.211673341263229 -1.5228787452825137 0.3491983503179625 1.2004591728058382 22.353441504927684 0.8811224213319281 0.19899021507064824 19.542636335120324 0.27526223545435047 0.17069497783054258 271.9629190653971 0.02999999999984968 1.5228787452825137 21.152982332121844 up TALPTS(ph)GSSAGELELLAGEVPAR ddPTM_PC-9_Lapatinib_30min_R1 1 TALPTSGSSAGELELLAGEVPAR 23 0 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 TALPT(0.006)S(0.981)GS(0.013)S(0.001)AGELELLAGEVPAR 200.4 1.4725999999999998e-65 0.0 6069.6 4843.7 6326.6 5494.8 6587.3 5681.4 5803.3 4232.1 7684.6 4599.1 True False 5983.046390971684 4832.48471024604 5806.451369382239 5898.905922115456 6199.84796513009 5438.41976599026 6103.76647823502 4428.738816040634 6819.079425574552 5394.048307084455 1.1091940691583442 0.8958919970922644 1.076455203739303 1.0935953084379926 1.1493868078614187 1.0082260032501986 1.1315743075972147 0.8210417415476241 1.2641858280391158 1.0 12.397152726532065 TALPTSGS(ph)SAGELELLAGEVPAR ddPTM_PC-9_AZD4547_30min_R2 1 TALPTSGSSAGELELLAGEVPAR 23 0 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 TALPT(0.01)S(0.064)GS(0.525)S(0.401)AGELELLAGEVPAR 101.05 5.0724e-06 3051700.0 3877.2 4934.9 7637.4 10727.0 8054.3 7447.9 6637.9 8631.2 6893.6 6572.4 True False 5110.068949230092 6530.00991777076 7536.123085811489 8254.055880497912 6936.099472337982 6982.181635613793 7228.6602406838 7297.446365244665 7257.981622436674 6342.302276482863 0.8057119838292998 1.0295961360882961 1.1882314587488665 1.3014289639117005 1.0936248652255045 1.1008907067554303 1.1397533459557005 1.1505989539955321 1.1443764907499179 1.0 12.630790923124096 -4.851042423184041 2.7793677718570358 1.1471351662846596 0.769455984593203 0.6605016960213907 0.07274266546196413 0.2163986594316695 2.5645217378965035 0.019040402623858275 0.1760581986158837 1.4091511416000961e-05 4.851042423184041 -0.37767918169145664 TALPTSGS(ph)SAGELELLAGEVPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TALPTSGSSAGELELLAGEVPAR 23 0 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 TALPTSGS(0.5)S(0.5)AGELELLAGEVPAR;TALPT(0.152)S(0.17)GS(0.349)S(0.329)AGELELLAGEVPAR 193.36 1.8445999999999997e-24 4792000.0 10059.900000000001 9472.6 13857.1 17490.6 15253.9 13015.5 15601.099999999999 13496.4 13238.8 12437.3 True False 11762.842377918125 10412.977125767524 14187.50581734439 16510.658387290285 12265.007796037362 12332.944267521752 14123.250865817261 13142.133800617834 13432.392404651055 14692.084036387376 0.8006244960745869 0.7087474520277766 0.9656564570558327 1.123779196089466 0.8348038144664189 0.8394278331771842 0.9612830168163138 0.8945043989722061 0.9142605209297411 1.0 13.842751432741771 -5.264861279788371 24.99086206592045 0.9376765736350868 0.7546859678852362 0.45557409677158844 0.08168659906391347 256.9999062926357 1876938.614819942 0.02235806369290731 0.049799238838957274 5.434238815624969e-06 5.264861279788371 -0.1829906057498506 TALPTSGSS(ph)AGELELLAGEVPAR ddPTM_PC-9_AZD4547_30min_R2 1 TALPTSGSSAGELELLAGEVPAR 23 0 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 TALPTS(0.006)GS(0.406)S(0.588)AGELELLAGEVPAR 110.98 8.184300000000001e-07 3232800.0 9899.6 11068.0 14443.0 21683.0 17687.0 16397.0 12958.0 19018.0 14887.0 16939.0 True False 13047.466875528275 14645.514553463443 14251.476383111449 16684.319349010555 15231.465349843169 15371.69299791342 14111.236897027782 16079.20509016394 15673.896427587139 16345.970765830336 0.7982069136452108 0.8959709253902783 0.871864790857376 1.0206992039828864 0.9318177285428081 0.940396457214181 0.8632853379700123 0.9836800347016377 0.9588844035101235 1.0 13.996647438970992 -4.678402034069578 1.1198668396866496 0.9486454629849048 0.7071140893586197 0.5122971493812638 0.04589417247637957 1.7366394299340875 1.560260673303993 0.014350546979401538 0.5243811048096959 2.0969977569846e-05 4.678402034069578 -0.24153137362628507 TALPTSGSS(ph)AGELELLAGEVPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TALPTSGSSAGELELLAGEVPAR 23 0 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 TALPTSGS(0.006)S(0.994)AGELELLAGEVPAR;TALPTS(0.001)GS(0.023)S(0.975)AGELELLAGEVPAR 202.22 8.784299999999997e-66 0.0 9883.099999999999 8583.1 12386.6 13134.5 15600.2 12210.3 12006.5 10863.9 10622.5 8260.6 True False 11556.113629877293 9435.173444268232 12681.943520442088 12398.61654762354 12543.452796972722 11569.970372995336 10869.157400467597 10578.734136253526 10777.833966704371 9758.181389126381 1.1842487005574995 0.9668987558257444 1.2996216215629768 1.2705868084640666 1.2854293537677002 1.1856687134231636 1.1138507235148534 1.0840886958753906 1.1044920704911467 1.0 13.252396585589574 -7.417446824636515 2.420942919784775 1.070494266922104 1.200616979720119 0.315453430703998 0.09118375946145808 0.4405691707436081 5.045991134294507 0.05114006675101181 0.029985039758694775 3.824310759581825e-08 7.417446824636515 0.1301227127980149 TALPTSGSS(ph)AGELELLAGEVPAR ddPTM_PC-9_Lapatinib_30min_R1 2 TALPTSGSSAGELELLAGEVPAR 23 0 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 TALPTSGS(0.027)S(0.973)AGELELLAGEVPAR;TALPTSGS(0.108)S(0.892)AGELELLAGEVPAR 220.17 4.488399999999999e-94 2265200.0 14899.9 17991.7 14925.4 11750.1 13054.8 13548.6 14125.0 10150.4 14365.5 10758.2 True False 14687.424693692983 17950.041324056754 13698.291225710116 12614.241551184543 12286.942330724323 12969.157961329187 14856.323385844202 10622.024639857007 12747.506114578657 12617.740535599583 1.164029697096244 1.4226034584728275 1.085637415594486 0.9997226932662652 0.9737830870795013 1.0278510581778186 1.177415508262252 0.8418325460004602 1.0102843752899304 1.0 13.623165968956464 -5.445988707044093 5.14299863266764 1.006891916891153 1.29108767234704 0.5854557243931839 0.09581315516504872 0.14100226712489233 6.613401836178626 0.02484440176934451 0.05253726157488812 3.5810574880246443e-06 5.445988707044093 0.28419575545588693 TALPTSGSSAGELELLAGEVPARS(ph)PGAFDMSGVR ddPTM_PC-9_AZD4547_30min_R2 3 TALPTSGSSAGELELLAGEVPARSPGAFDMSGVR 34 1 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 TALPTSGSSAGELELLAGEVPARS(0.995)PGAFDMS(0.004)GVR;TALPTSGSSAGELELLAGEVPARS(0.997)PGAFDMS(0.003)GVR;TALPT(0.001)S(0.005)GS(0.005)S(0.005)AGELELLAGEVPARS(0.79)PGAFDMS(0.194)GVR 85.291 2.4111999999999996e-11 50065000.0 19423.98 17321.6 30351.300000000003 58299.4 43328.7 29855.7 24977.1 35716.8 24850.0 37440.9 True False 25600.40159611737 22920.468457650197 29948.821930812876 44859.374046751174 37313.257912803194 27988.81835932204 27200.013512945854 30197.589250413697 26163.520267719512 36130.10548712301 0.7085614960421721 0.63438697863252 0.8289159836936214 1.2416065063175454 1.0327469961609126 0.7746674963154322 0.7528351535713093 0.8358013031867926 0.7241473534320112 1.0 15.140913846484962 -5.41182648836725 5.269950959877104 0.90442888649185 0.676535732330444 0.2833275428337504 0.14838661070880715 0.3167625983418015 12.564629971708186 0.043748273704424585 0.09320900720441619 3.874123950592455e-06 5.41182648836725 -0.2278931541614061 TALPTSGSSAGELELLAGEVPARS(ph)PGAFDMSGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TALPTSGSSAGELELLAGEVPARSPGAFDMSGVR 34 1 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 TALPTSGS(0.002)S(0.002)AGELELLAGEVPARS(0.609)PGAFDMS(0.386)GVR;TALPTS(0.001)GS(0.001)S(0.001)AGELELLAGEVPARS(0.953)PGAFDMS(0.045)GVR;TALPTSGSSAGELELLAGEVPARS(0.957)PGAFDMS(0.043)GVR 72.07300000000001 9.8786e-06 42072400.0 23012.5 17005.4 26280.1 37781.3 53643.2 56926.5 53916.1 66218.5 47051.1 39869.5 True False 26908.061732406968 18693.58372722665 26906.717251834263 35664.53624962727 43132.20004093323 53941.17412662418 48808.77668923925 64480.33453930034 47739.13332556405 47097.524743211645 0.5713264524859204 0.39691223326807706 0.5712979057506082 0.7572486334277629 0.915806091213956 1.1453080479436224 1.0363342225596315 1.3690811755153682 1.0136229788263953 1.0 15.523363619121444 -6.169304114194762 1.2440617259227333 1.1404729052392566 0.4727013039716536 0.8475953396533702 0.11086889027318723 0.15187585747571855 0.479136168486944 0.04156028185459284 0.06581962356465132 6.771671560518373e-07 6.169304114194762 -0.6677716012676029 TALPTSGSSAGELELLAGEVPARS(ph)PGAFDMSGVR ddPTM_PC-9_Lapatinib_30min_R1 4 TALPTSGSSAGELELLAGEVPARSPGAFDMSGVR 34 1 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 TALPTSGSSAGELELLAGEVPARS(0.994)PGAFDMS(0.006)GVR;TALPTSGSSAGELELLAGEVPARS(0.937)PGAFDMS(0.063)GVR;TALPTSGSSAGELELLAGEVPARS(0.998)PGAFDMS(0.002)GVR;TALPT(0.001)S(0.001)GS(0.004)S(0.011)AGELELLAGEVPARS(0.968)PGAFDMS(0.015)GVR 111.89 2.3537e-21 27196500.0 69991.6 41264.700000000004 59923.100000000006 52697.600000000006 56563.0 65187.100000000006 56652.700000000004 51543.7 75213.20000000001 46207.9 True False 68993.50694911249 41169.15412244564 54996.45402785521 56573.157298040234 53236.07554713665 62399.199691552065 59585.89960220993 53938.608471527965 66741.89738589173 54194.87394684351 1.2730633346759708 0.7596503345099757 1.0147906992421076 1.0438839170200753 0.9823083194058669 1.1513856412463601 1.0994748259891545 0.995271407484647 1.2315167934767197 1.0 15.725868779445884 -6.747226741453635 24.88885246781765 1.0954807702412703 1.0021896950591296 0.08138419048485457 0.13239937620033349 522.4581148996007 914915.2311329092 0.04162883901122901 0.04143990429959268 1.789671237953764e-07 6.747226741453635 -0.09329107518214075 TAMPS(ph)PGVSQNK ddPTM_PC-9_AZD4547_30min_R2 4 TAMPSPGVSQNK 12 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 T(0.006)AMPS(0.973)PGVS(0.021)QNK;T(0.001)AMPS(0.972)PGVS(0.027)QNK;T(0.109)AMPS(0.885)PGVS(0.006)QNK;TAMPS(0.984)PGVS(0.016)QNK 114.71 0.00066593 44018100.0 156270.0 178391.0 204862.0 230728.0 211390.0 218311.0 210602.0 250102.0 224892.0 215943.0 True False 205960.60938207645 236052.4021238612 202145.39602554715 177537.2243120649 182042.14735700496 204659.9786587468 229345.17000986575 211454.48267221468 236779.3319938825 208382.90129793392 0.9883757645144109 1.1327820116409983 0.970067096515425 0.8519759692674226 0.8735944562780203 0.9821342220690925 1.1005949556387122 1.014740083544039 1.136270445027296 1.0 17.66887737765441 -7.146029246954469 5.840135658385323 1.0636357383416668 0.9635037921587208 0.26320965606177327 0.07937982099526525 0.36702798350846194 16.329741497549 0.033993578315660467 0.02623477244635674 7.144482109398874e-08 7.146029246954469 -0.10013194618294596 TAMPS(ph)PGVSQNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 TAMPSPGVSQNK 12 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 T(0.001)AMPS(0.988)PGVS(0.011)QNK;T(0.014)AMPS(0.964)PGVS(0.022)QNK;T(0.005)AMPS(0.967)PGVS(0.029)QNK;T(0.004)AMPS(0.954)PGVS(0.042)QNK;T(0.032)AMPS(0.96)PGVS(0.008)QNK;T(0.006)AMPS(0.989)PGVS(0.005)QNK 127.52 0.00020409 42146200.0 187738.0 203202.0 188722.0 213767.0 265929.0 208786.0 254057.0 208817.0 197185.0 197848.0 True False 219518.33540548058 223374.55164476583 193221.8482121709 201790.32803196515 213822.12143729976 197836.89461325304 229990.8817466031 203335.77500990042 200068.4575876304 233716.27623609366 0.9392513818067565 0.9557509440169203 0.8267368080817084 0.8633986955539297 0.9148790357300688 0.8464831709598339 0.9840601837857142 0.8700111874300799 0.8560313419743468 1.0 17.834398682787054 TAMPS(ph)PGVSQNK ddPTM_PC-9_Lapatinib_30min_R1 7 TAMPSPGVSQNK 12 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 T(0.011)AMPS(0.988)PGVS(0.001)QNK;TAMPS(0.996)PGVS(0.004)QNK;T(0.001)AMPS(0.919)PGVS(0.079)QNK;TAMPS(0.971)PGVS(0.029)QNK;T(0.008)AMPS(0.83)PGVS(0.161)QNK;TAMPS(0.995)PGVS(0.005)QNK;T(0.004)AMPS(0.833)PGVS(0.163)QNK 135.04 5.0672e-05 34273000.0 175003.0 234359.0 246461.0 228647.0 311941.0 303928.0 322607.0 302844.0 295814.0 278654.0 True False 172507.42512838062 233816.3561344746 226197.9279469725 245462.46312403234 293593.24367960216 290929.7079307719 339310.01193182566 316915.23782637727 262496.31226048304 326818.97261688416 0.5278378539259521 0.7154307911265833 0.6921199406992036 0.7510655246192742 0.8983359849912046 0.8901861039500186 1.038220055631789 0.969696573270498 0.8031856601183194 1.0 18.31813221222206 -5.853860970979054 0.8299859304342538 0.9552341523321972 0.5727665468339982 0.785914644973051 0.07023684894759469 0.3674945744609115 0.47643704246643326 0.03311599368052769 0.09757212336156583 1.4000354387983903e-06 5.853860970979054 -0.382467605498199 TAMSS(ph)ETPT(ph)S(ph)RQLSEY(ph)LKHAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TAMSSETPTSRQLSEYLKHAK 21 2 P22079 P22079 LPO Lactoperoxidase 4 T(0.3)AMS(0.35)S(0.368)ET(0.12)PT(0.938)S(0.921)RQLS(0.459)EY(0.545)LKHAK 40.141999999999996 0.046188 0.0 2569.1 2278.5 2162.5 3207.9 4418.9 3981.5 3229.0 4037.3 3212.1 2322.2 True False 3003.997887962052 2504.6944219180928 2214.062201326919 3028.1717631521215 3553.048266339067 3772.7031309698327 2923.1257440644536 3931.3251528729447 3259.070885803821 2743.196477474914 1.0950720856594287 0.913056881810974 0.8071103253110553 1.1038843874353195 1.2952219410873602 1.375294537576313 1.0655910971259204 1.4331183293482834 1.188055945888267 1.0 11.421642241491865 -5.992644773816255 5.062251050212082 1.2445736831919487 0.9361132597068884 0.45890515670733756 0.13897342106231445 0.14242925931005507 10.759208616915316 0.038878955415797306 0.055839749707338085 1.0170802618575406e-06 5.992644773816255 -0.3084604234850603 TANLTGTDSPETDASAS(ph)LQQNKSPR ddPTM_PC-9_AZD4547_30min_R2 1 TANLTGTDSPETDASASLQQNKSPR 25 1 R4GN62;A0A087WZG6;A0A087X1S9;Q8TEW8-5;Q8TEW8-2;Q8TEW8;A0A087WYL6;Q8TEW8-6;Q8TEW8-3 R4GN62 PARD3B Partitioning defective 3 homolog B 1 TANLT(0.002)GT(0.004)DS(0.01)PET(0.016)DAS(0.036)AS(0.654)LQQNKS(0.278)PR 43.303000000000004 0.029712 4874400.0 4610.1 4524.1 1606.6 5919.6 7729.0 5961.4 3944.8 7678.8 7602.8 8299.0 True False 6076.015903963078 5986.426851402597 1585.2954342662083 4554.927676908308 6655.961762251249 5588.63271560414 4295.879557909801 6492.217901269891 8004.668486576171 8008.454536019 0.7587001807446687 0.7475133715847312 0.1979527294731023 0.5687648792188262 0.8311168818297275 0.6978415985841692 0.5364180490241356 0.8106705072833154 0.9995272434368202 1.0 12.967308144231943 -8.026172259027419 3.1083063531873854 0.9956764637926828 0.6178650262002691 0.456907233395325 0.16621277364733622 0.256474702548374 4.84092694932153 0.13422086656962756 0.04794350860626056 9.41516078507898e-09 8.026172259027419 -0.37781143759241376 TANS(ph)PGSGARPDPVR ddPTM_PC-9_Lapatinib_30min_R1 1 TANSPGSGARPDPVR 15 1 Q13206;A0A3B3ISR7;E9PIF2 Q13206 DDX10 Probable ATP-dependent RNA helicase DDX10 1 T(0.137)ANS(0.768)PGS(0.095)GARPDPVR 57.788000000000004 0.028895999999999998 26356000.0 30263.0 41953.0 47642.0 44730.0 41856.0 41815.0 42116.0 44044.0 47151.0 36443.0 True False 29831.444070445505 41855.86040608462 43725.05866343827 48019.593414905794 39394.11237206217 40026.669925525886 44296.56040482932 46090.44503052709 41840.35785795821 42742.12399275489 0.6979401415685884 0.9792648679129634 1.02299686068128 1.1234723249374663 0.9216695075504382 0.9364689020206555 1.0363677858484037 1.0783377316096825 0.9789021683866358 1.0 15.383370981456306 -4.759537168571853 3.948473310654601 1.013455754731077 0.6611836095373533 0.7288654186743574 0.05715376382568954 0.1399850827087809 3.9971074359788417 0.015119462913473205 0.14693355110798045 1.7396538054845352e-05 4.759537168571853 -0.35227214519372363 TANSPGS(ph)GARPDPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TANSPGSGARPDPVR 15 1 Q13206;A0A3B3ISR7;E9PIF2 Q13206 DDX10 Probable ATP-dependent RNA helicase DDX10 1 TANS(0.056)PGS(0.944)GARPDPVR;T(0.039)ANS(0.073)PGS(0.888)GARPDPVR 151.73 0.00070686 16397400.0 18418.4 20754.9 23239.0 22315.0 22807.4 20902.9 22947.0 22752.0 17703.0 18268.1 True False 21536.271340018026 22815.309307644424 23793.105894398293 21064.762896206135 18338.453694290823 19806.715126547606 20773.29403810687 22154.784107736676 17961.872884214397 21579.961919799967 0.9979754097831908 1.0572451143535617 1.1025555088013261 0.9761260457498245 0.8497908273630915 0.917829011939758 0.9626195873426001 1.0266368490395388 0.8323403419787356 1.0 14.397404698584637 -5.962846339863074 6.999956619349402 0.9318563122875717 1.0516551105572132 0.44246686036503546 0.060768041893844806 0.18105037820443293 25.48015846765202 0.01723556929782411 0.025494572749247192 1.0893154418902944e-06 5.962846339863074 0.11979879826964146 TAPAAAVS(ph)PMQR ddPTM_PC-9_AZD4547_30min_R2 1 TAPAAAVSPMQR 12 0 Q5M775;Q5M775-4;J3KSG2 Q5M775 SPECC1 Cytospin-B 1 TAPAAAVS(1)PMQR 80.318 0.012702 6435800.0 24168.0 22210.0 31375.0 45089.0 41438.0 42262.0 29637.0 38287.0 33339.0 34372.0 True False 31852.921274371394 29388.948159778003 30958.946999939177 34694.42766810573 35685.048971945565 39619.35045909723 32274.635585523403 32370.62389773407 35101.231477082554 33168.646742022545 0.9603322535922392 0.8860460418647136 0.9333798644463893 1.0460006987306516 1.0758668947061654 1.1944819686870751 0.9730464988984164 0.9759404460937071 1.0582654079948202 1.0 15.017532531910549 -5.746295013522422 5.113500632077776 1.0500793259077947 0.9205547411357656 0.43915287429466565 0.06190271057132267 0.17061516289471287 12.206416522327576 0.01846964489367862 0.030889153777831236 1.7935148895038992e-06 5.746295013522422 -0.1295245847720291 TAPAAAVS(ph)PMQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TAPAAAVSPMQR 12 0 Q5M775;Q5M775-4;J3KSG2 Q5M775 SPECC1 Cytospin-B 1 T(0.004)APAAAVS(0.996)PMQR;TAPAAAVS(1)PMQR 89.43 0.025957 6441000.0 59013.0 49995.0 61583.0 73586.0 82399.0 74920.0 75621.0 81534.0 68069.0 58514.0 True False 69002.73534012098 54958.173194555595 63051.372274828085 69463.21498903101 66253.50745617063 70991.06331087767 68457.63143137122 79393.81889241394 69064.38035110364 69122.1250034308 0.9982727720928155 0.795088015477357 0.9121735229016555 1.004934599241318 0.9584992859071131 1.0270382067587491 0.9903866732681236 1.148602113845217 0.9991645995790162 1.0 16.07685995012934 -6.1983822998334235 0.9682373142023898 1.0446992816141272 0.8885986172519236 0.38755733707560214 0.06622394947173224 0.5253892877616266 1.035196072050588 0.029907926227343146 0.05085443777917209 6.333119752775589e-07 6.1983822998334235 -0.1561006643622036 TAPAAAVS(ph)PMQR ddPTM_PC-9_Lapatinib_30min_R1 2 TAPAAAVSPMQR 12 0 Q5M775;Q5M775-4;J3KSG2 Q5M775 SPECC1 Cytospin-B 1 T(0.042)APAAAVS(0.958)PMQR;T(0.014)APAAAVS(0.986)PMQR 120.6 0.00048522 9994500.0 42095.0 32517.0 38721.0 33634.0 36109.0 37323.0 27619.0 31039.0 33230.0 23776.0 True False 41494.71758072246 32441.708884338543 35537.508847382414 36107.55655973488 33985.139613025414 35726.78229416244 29048.976679195115 32481.185253440413 29487.28747258702 27885.649920471395 1.4880312167392014 1.1633836391427426 1.2744013120990105 1.2948436440503266 1.21873220491362 1.281188797681015 1.0417177566971354 1.1647992908924583 1.0574359054453966 1.0 14.767235275276589 -1.5228800316244109 0.10819197149766645 0.8738383045284721 2.3814637229171067 0.64060790396353 0.08314801825844786 74.02518604387278 0.5628192041230062 0.8010550868004909 16.6347622366379 0.029999911142630963 1.5228800316244109 1.5076254183886346 TAPAAPAEDAVAAAAAAPSEPSEPS(ph)RPSPQPKPR ddPTM_PC-9_AZD4547_30min_R2 2 TAPAAPAEDAVAAAAAAPSEPSEPSRPSPQPKPR 34 2 Q53GA4 Q53GA4 PHLDA2 Pleckstrin homology-like domain family A member 2 1 TAPAAPAEDAVAAAAAAPS(0.004)EPS(0.135)EPS(0.431)RPS(0.431)PQPKPR;TAPAAPAEDAVAAAAAAPS(0.162)EPS(0.162)EPS(0.562)RPS(0.115)PQPKPR 97.059 3.0914000000000003e-16 46026000.0 30305.0 29196.0 52824.0 71252.0 64355.0 62701.0 57588.0 62409.0 61902.0 71748.0 True False 39941.35961684153 38633.03604110215 52123.51924541157 54825.95223242629 55420.4190981601 58780.29655803924 62713.220437261574 52765.123066150016 65174.013344562314 69236.1243583917 0.5768861268156827 0.557989581293189 0.7528370446560675 0.7918691685950957 0.8004552480621762 0.8489830576560116 0.9057875642003708 0.7621039385887386 0.9413296013970627 1.0 16.07923734854314 -4.020053810836398 0.31571713243352717 0.9376844088751749 2.801679964576013e-20 0.8244137528031608 0.057034080778624895 4.935247967302461 0.27457934933468847 0.0593287786933025 1.9409593013104263 9.548742659219843e-05 4.020053810836398 -0.9376844088751749 TAPAAPAEDAVAAAAAAPSEPSEPS(ph)RPSPQPKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TAPAAPAEDAVAAAAAAPSEPSEPSRPSPQPKPR 34 2 Q53GA4 Q53GA4 PHLDA2 Pleckstrin homology-like domain family A member 2 1 TAPAAPAEDAVAAAAAAPS(0.044)EPS(0.158)EPS(0.399)RPS(0.399)PQPKPR;TAPAAPAEDAVAAAAAAPS(0.051)EPS(0.301)EPS(0.324)RPS(0.324)PQPKPR;TAPAAPAEDAVAAAAAAPS(0.073)EPS(0.073)EPS(0.427)RPS(0.427)PQPKPR 102.06 7.9164e-17 30621900.0 59628.0 69084.0 98607.0 111038.0 138178.0 130638.0 128135.0 141737.0 122049.0 94077.0 True False 69721.84269331714 75942.2029597497 100958.16484912987 104816.90085005305 111103.0128190726 123787.1133049445 115997.12518293578 138016.55393276535 123833.7357309767 111132.41538687792 0.6273762920620334 0.6833488023757707 0.9084492989527033 0.9431712654238721 0.9997354276184588 1.1138704479157824 1.0437739950051717 1.2419108632913038 1.1142899693116766 1.0 16.761920161522873 -5.250013998225635 0.6611438891330341 1.1244287484915119 0.44502465192217994 0.8687842349464144 0.06547288698619268 0.6241316185841537 0.30997152399825934 0.03199524019048655 0.29246346213488494 5.623232000374378e-06 5.250013998225635 -0.679404096569332 TAPAAPAEDAVAAAAAAPSEPSEPS(ph)RPSPQPKPR ddPTM_PC-9_Lapatinib_30min_R1 4 TAPAAPAEDAVAAAAAAPSEPSEPSRPSPQPKPR 34 2 Q53GA4 Q53GA4 PHLDA2 Pleckstrin homology-like domain family A member 2 1 TAPAAPAEDAVAAAAAAPS(0.008)EPS(0.162)EPS(0.796)RPS(0.034)PQPKPR;TAPAAPAEDAVAAAAAAPSEPS(0.013)EPS(0.493)RPS(0.493)PQPKPR;TAPAAPAEDAVAAAAAAPS(0.002)EPS(0.076)EPS(0.864)RPS(0.057)PQPKPR;TAPAAPAEDAVAAAAAAPS(0.07)EPS(0.262)EPS(0.334)RPS(0.334)PQPKPR 135.06 1.2696e-24 62173600.0 171171.0 149720.0 155137.0 147122.0 141148.0 122876.0 97449.9 102473.2 141711.0 92635.5 True False 168730.07015108308 149373.33253876958 142382.23470613803 157941.84266460486 132845.952147645 117620.8799179461 102495.37899597717 107234.47896880883 125750.01489701417 108647.42274595535 1.5530057307076293 1.3748446927088323 1.31049804134851 1.4537099792409445 1.2227252961008732 1.082592453140586 0.9433760728557438 0.9869951468572767 1.1574136939359245 1.0 16.729294426814 -6.5777205458640315 2.143065843064338 1.02047836140042 1.4139609973884657 0.8431438908761624 0.0790494171726315 0.12123146238789118 1.1294208376488537 0.029786709162667173 0.03097000501633883 2.6441096071282466e-07 6.5777205458640315 0.39348263598804567 TAPAAPAEDAVAAAAAAPSEPSEPSRPS(ph)PQPK ddPTM_PC-9_Lapatinib_30min_R1 1 TAPAAPAEDAVAAAAAAPSEPSEPSRPSPQPK 32 1 Q53GA4 Q53GA4 PHLDA2 Pleckstrin homology-like domain family A member 2 1 TAPAAPAEDAVAAAAAAPS(0.065)EPS(0.065)EPS(0.207)RPS(0.663)PQPK 146.34 2.4385e-15 4900400.0 9751.0 17520.0 15131.0 14136.0 16903.0 13055.0 15579.0 13818.0 14229.0 13811.0 True False 9611.948951885604 17479.433516425586 13886.987587349066 15175.608596313616 15908.798772576605 12496.668082691389 16385.604391367553 14460.03472508907 12626.380181987377 16198.212947999265 0.5933956407872037 1.079096414681014 0.8573160281279255 0.9368693105240379 0.9821329564963889 0.7714843682330355 1.011568649206543 0.892693210757864 0.7794921712982501 1.0 13.983547037519156 -4.742572428600982 24.991017867711363 0.9182507343470168 0.5933945695200289 0.5183594799048268 0.0953156163689242 1026.3705275714296 1359451.4544011755 0.022448344762100423 0.789476576898082 1.8089542003465078e-05 4.742572428600982 -0.32485616482698787 TAPAAPAEDAVAAAAAAPSEPSEPSRPS(ph)PQPKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TAPAAPAEDAVAAAAAAPSEPSEPSRPSPQPKPR 34 2 Q53GA4 Q53GA4 PHLDA2 Pleckstrin homology-like domain family A member 2 1 TAPAAPAEDAVAAAAAAPS(0.002)EPS(0.067)EPS(0.251)RPS(0.68)PQPKPR 84.10700000000001 5.0670000000000004e-11 5041400.0 3503.1 4055.0 7295.6 9233.3 8105.7 8455.7 7544.3 9751.8 9091.9 6536.7 True False 4096.1056406211765 4457.553601438603 7469.554772717079 8715.988135762493 6517.446272254316 8012.268206590882 6829.649287997975 9495.825582886175 9224.851837315087 7721.751965511267 0.530463249650621 0.5772723109144134 0.9673393817982484 1.128757848567517 0.8440372471641269 1.0376230993144027 0.8844688768173578 1.229750142881913 1.194657880558366 1.0 12.91471249811384 -5.28128348245189 3.578218631241455 1.0404599234921112 0.5367378325322126 0.7402812136909 0.11507783653503358 0.11480263378422746 3.170554569189543 0.03223000945199392 0.08452546217641248 5.232587718662743e-06 5.28128348245189 -0.5037220909598986 TAPATGQLPGRSS(ph)PAGSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TAPATGQLPGRSSPAGSPR 19 1 Q9NQU5-2;Q9NQU5 Q9NQU5-2 PAK6 Serine/threonine-protein kinase PAK 6 1 T(0.001)APAT(0.006)GQLPGRS(0.184)S(0.674)PAGS(0.134)PR 47.618 0.036819 5537500.0 9938.5 3249.1 6929.2 8460.4 10185.0 12408.0 9857.0 12179.0 6235.7 5890.1 True False 11620.891755677427 3571.649175446159 7094.418407137339 7986.391216986886 8189.322363634257 11757.302636964369 8923.273601499945 11859.314154717162 6326.885315714608 6957.928503994053 1.6701654449318784 0.5133207639882946 1.019616456688932 1.1478116241640692 1.1769770785850053 1.6897705445256206 1.2824612377631828 1.7044317353806626 0.9093058820714802 1.0 12.764442139322224 -6.31498094339 2.6078578220285684 1.3605008979745987 1.0296516911008882 0.0651213077869941 0.35561477919723894 0.5500721420922764 7.370668597630463 0.1128262101866775 0.1372914437857009 4.841936132752148e-07 6.31498094339 -0.33084920687371056 TAPATGQLPGRSS(ph)PAGSPR ddPTM_PC-9_Lapatinib_30min_R1 2 TAPATGQLPGRSSPAGSPR 19 1 Q9NQU5-2;Q9NQU5 Q9NQU5-2 PAK6 Serine/threonine-protein kinase PAK 6 1 TAPATGQLPGRS(0.016)S(0.981)PAGS(0.003)PR;TAPATGQLPGRS(0.015)S(0.942)PAGS(0.043)PR 212.74 1.5282999999999996e-72 10196000.0 44267.0 25534.6 31135.7 26136.7 21269.7 16034.9 12909.199999999999 10391.5 24562.3 19547.5 True False 43635.7444624264 25475.476202541155 28575.84293327765 28058.88010747525 20018.658063839124 15349.124706177572 13577.57521079928 10874.327026035835 21795.835121514425 22926.2593295935 1.9033085090379678 1.1111920107113633 1.2464241341103386 1.223875194993389 0.8731759410048543 0.6694997419995478 0.5922281090693752 0.47431754433655554 0.9506930375414575 1.0 14.484713362166275 -3.027174533836859 0.44087811145544076 0.6918580127990475 6.688831884152655 0.7093364567453311 0.2094541376550824 12.22570843458244 0.5363281637058795 0.14244834744320123 53.29832006079521 0.0009393457313656572 3.027174533836859 5.996973871353607 TAPPALPT(ph)GYDSEEEEESRPMSYDEK ddPTM_PC-9_AZD4547_30min_R2 1 TAPPALPTGYDSEEEEESRPMSYDEK 26 1 H0Y6K2;A0A140T9E9;A0A0G2JK44;P25440-4;P25440-3;P25440;P25440-2;A0A0G2JHN8;A0A140T9I1 H0Y6K2 BRD2 Bromodomain-containing protein 2 1 TAPPALPT(0.366)GY(0.314)DS(0.314)EEEEES(0.003)RPMS(0.001)Y(0.001)DEK 49.515 0.015944 8262800.0 14849.0 15854.0 18536.0 20880.0 17806.0 20293.0 16611.0 23947.0 18455.0 18000.0 True False 19570.673121612912 20978.495458132387 18290.200528792746 16066.438592784221 15333.944253932692 19024.07550202214 18089.34682022907 20246.541397316 19430.493623370778 17369.825478773593 1.126705224846894 1.207755108637602 1.0529870061817188 0.924962580218083 0.8827920736838257 1.095236997359017 1.0414236367737115 1.1656157065053896 1.1186349366097763 1.0 14.084295638366164 -5.346993893671135 5.987270028913736 1.0332049759662871 1.1664705905547337 0.29325133334581466 0.0822502932525292 0.29409174042900976 16.318696153862458 0.024325102523744382 0.05174396119768935 4.4978617899625e-06 5.346993893671135 0.13326561458844655 TAPPALPT(ph)GYDSEEEEESRPMSYDEK ddPTM_PC-9_Lapatinib_30min_R1 1 TAPPALPTGYDSEEEEESRPMSYDEK 26 1 H0Y6K2;A0A140T9E9;A0A0G2JK44;P25440-4;P25440-3;P25440;P25440-2;A0A0G2JHN8;A0A140T9I1 H0Y6K2 BRD2 Bromodomain-containing protein 2 1 T(0.001)APPALPT(0.565)GY(0.161)DS(0.188)EEEEES(0.024)RPMS(0.031)Y(0.029)DEK 54.306000000000004 0.003886 6439900.0 20326.0 27400.0 30548.0 30018.0 32845.0 40253.0 36377.0 29535.0 33073.0 33318.0 True False 20036.147512668114 27336.55698345097 28036.461358690078 32225.623857112514 30913.121675754515 38531.47302432601 38260.423065972 30907.30392281849 29347.97046587032 39076.971906555606 0.5127354176925573 0.6995566864500304 0.7174676028053915 0.8246704461689955 0.79108283389196 0.986040400378667 0.9791040912142268 0.7909339545737278 0.7510298017986103 1.0 15.254031056050879 -4.441736880682118 0.6275371641921752 0.8894173275484569 0.128717742362617 0.6625810341175289 0.08397696938461906 3.36155095822439 0.7400061082308476 0.04186661280505218 2.0221120204127323 3.616288908171747e-05 4.441736880682118 -0.7606995851858399 TAPPALPT(ph)GYDSEEEEESRPMSYDEKR ddPTM_PC-9_Lapatinib_30min_R1 2 TAPPALPTGYDSEEEEESRPMSYDEKR 27 2 H0Y6K2;A0A140T9E9;A0A0G2JK44;P25440-4;P25440-3;P25440;P25440-2;A0A0G2JHN8;A0A140T9I1 H0Y6K2 BRD2 Bromodomain-containing protein 2 1 T(0.001)APPALPT(0.413)GY(0.413)DS(0.041)EEEEES(0.026)RPMS(0.056)Y(0.05)DEKR;TAPPALPT(0.437)GY(0.388)DS(0.117)EEEEES(0.004)RPMS(0.028)Y(0.026)DEKR 51.301 0.007072 18437500.0 87302.0 37176.0 58821.0 42681.0 43244.0 48788.0 31874.0 33725.0 53748.0 31754.0 True False 86057.05747077403 37089.921256086636 53984.964435626185 45819.903119642164 40700.47294097514 46701.450970382815 33524.27975932023 35291.9866191655 47694.334248468476 37242.636590454604 2.3107133476374417 0.9958994489018774 1.4495473301012929 1.2303077148782193 1.0928461748974772 1.253978108047069 0.9001586039134672 0.9476232042124252 1.2806379626917357 1.0 15.184667591579501 -4.75730157663679 24.999986436335348 1.1352329857980954 2.310715062010935 0.8217473683258727 0.16523674978849934 50.47079180217196 304896.37407880713 0.04215796948275654 0.316808334833468 1.7486320066054784e-05 4.75730157663679 1.1754820762128397 TAPPALPTGYDS(ph)EEEEESRPMSYDEK ddPTM_PC-9_Lapatinib_30min_R1 1 TAPPALPTGYDSEEEEESRPMSYDEK 26 1 H0Y6K2;A0A140T9E9;A0A0G2JK44;P25440-4;P25440-3;P25440;P25440-2;A0A0G2JHN8;A0A140T9I1 H0Y6K2 BRD2 Bromodomain-containing protein 2 1 TAPPALPT(0.311)GY(0.311)DS(0.346)EEEEES(0.012)RPMS(0.013)Y(0.008)DEK 49.577 0.01151 7113800.0 9212.7 13948.0 14274.0 7317.0 13210.0 13613.0 12798.0 14058.0 11967.0 10551.0 True False 9081.325208597733 13915.704262962561 13100.446819233408 7855.116588796465 12433.01377185926 13030.803723452915 13460.617818905073 14711.186001252152 10619.150441903366 12374.726291676216 0.7338606927174002 1.1245262266788782 1.0586453801443143 0.634770935829115 1.0047102035882807 1.0530175307568626 1.0877507511385747 1.188809001064334 0.8581321470557514 1.0 13.595108995084455 -6.508888324504528 24.63234358868781 1.0498564671378374 0.9048789132162371 0.1726282865484272 0.1530007443942112 1023.2346546515246 1801569.1624040327 0.04889158125177294 0.053252969655016 3.0982158792484917e-07 6.508888324504528 -0.14497755392160028 TAPPAS(ph)PEAR ddPTM_PC-9_AZD4547_30min_R2 4 TAPPASPEAR 10 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 TAPPAS(1)PEAR;T(0.001)APPAS(0.999)PEAR;TAPPAS(1)PEAR;TAPPAS(1)PEAR 123.01 0.00049114 333658000.0 442697.0 477573.0 612072.0 828352.0 765045.0 589837.0 474550.0 647035.0 525359.0 555884.0 True False 583465.4373303719 631939.132800976 603955.5253592593 637388.2443108242 658831.7073879541 552954.3991468098 516784.0306748366 547050.6081351473 553128.4041983446 536422.6703579219 1.087697201427116 1.1780619420490226 1.1258948563010527 1.1882201844406282 1.2281951226042631 1.030818475247993 0.9633896164940575 1.0198126186019207 1.0311428557433562 1.0 19.033010684314952 -6.875240400645444 6.267277397247082 1.004408154959621 1.16153596423193 0.7968284529152332 0.038669161414947695 0.0946306547475041 4.845593664076546 0.013956641309342974 0.012316939346204989 1.3327834750501367e-07 6.875240400645444 0.15712780927230896 TAPPAS(ph)PEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TAPPASPEAR 10 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 TAPPAS(1)PEAR;TAPPAS(1)PEAR 124.39 0.00041448 188048000.0 142607.0 186071.0 187012.0 190221.0 226159.0 199812.0 193699.0 180663.0 167850.0 165693.0 True False 166747.54848336143 204542.89917960105 191471.07532695925 179563.53407480262 181844.7674459652 189333.50697107703 175350.4284606817 175920.7876782712 170304.4887089981 195731.82927493335 0.851918408472751 1.0450160300310243 0.9782316756362132 0.9173956772384728 0.9290505694428381 0.9673107724606765 0.8958707896934685 0.8987847726654887 0.8700909266513884 1.0 17.578518855865113 -7.264445454043753 24.882449978119872 0.9077520191118981 0.9516574252692851 0.062436186647652936 0.056079835642796734 553.7751485305029 4583793.977174163 0.02213349768147129 0.015686395340141372 5.439444450607566e-08 7.264445454043753 0.04390540615738703 TAPPAS(ph)PEAR ddPTM_PC-9_Lapatinib_30min_R1 3 TAPPASPEAR 10 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 TAPPAS(1)PEAR;TAPPAS(1)PEAR;TAPPAS(1)PEAR 139.32 0.00012089 225549000.0 815170.0 617410.0 691810.0 671220.0 684110.0 623990.0 599090.0 592550.0 719240.0 548940.0 True False 803545.5263161317 615980.4250785577 634932.052263827 720583.7579242798 643871.9948120088 597303.402291735 630107.9488301175 620082.0362101254 638231.6172670325 643823.5475834277 1.248083468416487 0.9567534884218224 0.9861895462615886 1.1192255403347224 1.0000752492336804 0.9277439517919084 0.9786966494083801 0.9631241953444925 0.9913144986116392 1.0 19.29630581819955 -6.507163097059102 19.592580804768996 0.969570929551259 1.0620626899425134 0.29279105278635287 0.07615190719108555 59.4840387481243 74158.759354908 0.023684699647021086 0.025928112185275208 3.1105479674405153e-07 6.507163097059102 0.0924917603912544 TAPS(ph)PLVEAK ddPTM_PC-9_AZD4547_30min_R2 3 TAPSPLVEAK 10 0 Q8TEH3;Q8TEH3-7;Q8TEH3-6;A0A0A0MS48;Q8TEH3-4;Q8TEH3-3;Q8TEH3-5;Q8TEH3-2 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 T(0.108)APS(0.892)PLVEAK;T(0.074)APS(0.926)PLVEAK;T(0.013)APS(0.987)PLVEAK 105.36 0.0024718000000000006 21697800.0 122609.0 137444.0 212010.0 243871.0 227946.0 255434.0 241218.0 277942.0 231157.0 269382.0 True False 161596.11157437158 181870.08513608863 209198.60887512707 187650.3087193908 196299.63253436712 239461.6716002329 262685.9346988148 234992.45037177094 243375.48710363128 259951.01817349947 0.6216406179510221 0.6996321322915644 0.8047616445014321 0.7218679505003789 0.7551408488938889 0.9211799718376508 1.0105208917608084 0.9039874204875382 0.9362359448086287 1.0 17.987880280400354 -6.755789551232972 3.246838155150464 0.9566707116023117 0.7193456884319909 0.8461302014529762 0.05028654203367742 0.09928391086592946 2.1777241148502693 0.01911840004137544 0.017865979907321642 1.7547305965309086e-07 6.755789551232972 -0.23732502317032078 TAPS(ph)PLVEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TAPSPLVEAK 10 0 Q8TEH3;Q8TEH3-7;Q8TEH3-6;A0A0A0MS48;Q8TEH3-4;Q8TEH3-3;Q8TEH3-5;Q8TEH3-2 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 T(0.043)APS(0.957)PLVEAK;T(0.017)APS(0.983)PLVEAK;T(0.059)APS(0.941)PLVEAK 95.094 0.006049499999999999 15922700.0 127782.0 139773.0 157164.0 185540.0 208030.0 162302.0 165454.0 146926.0 125229.0 108235.0 True False 149412.96879045866 153648.73971242405 160911.38580778908 175144.79532879614 167268.01485585034 153790.5974036582 149780.99933677312 143069.3481809648 127060.23721500815 127857.14871221158 1.1685929984780608 1.2017219315461642 1.258524747567912 1.3698474985002393 1.3082413970637423 1.202831432991042 1.1714714495464704 1.1189780909551936 0.993767172932996 1.0 16.964173300822637 -7.8309313684402 1.2572514864419484 0.9905681815176517 1.2598755566463093 0.7707344427608667 0.05473040752628258 0.24315683074099123 0.6954289836145885 0.05348244821121787 0.01995901508477909 1.4759397576166841e-08 7.8309313684402 0.26930737512865766 TAPS(ph)PLVEAK ddPTM_PC-9_Lapatinib_30min_R1 1 TAPSPLVEAK 10 0 Q8TEH3;Q8TEH3-7;Q8TEH3-6;A0A0A0MS48;Q8TEH3-4;Q8TEH3-3;Q8TEH3-5;Q8TEH3-2 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 T(0.192)APS(0.808)PLVEAK 94.402 0.0063163 9231500.0 94872.0 122720.0 127360.0 129850.0 114790.0 115180.0 102910.0 90507.0 99618.0 81607.0 True False 93519.10788260616 122435.84937989441 116888.95242381732 139399.60216690192 108038.27788582326 110254.019897694 108238.17625750274 94712.28563204783 88397.97181595469 95712.66121550776 0.9770818896367057 1.279202227009616 1.2212485886337312 1.4564384732029143 1.1287772851970233 1.151927221514035 1.130865811094651 0.989548137406738 0.9235765748579153 1.0 16.546422161780157 -7.524525543906159 1.3175067076807423 0.9520458212806842 1.2262889280191256 0.44581789034972197 0.11534721881420226 0.4124394809805797 1.3542524646185374 0.08582400866576108 0.03982291954423413 2.988645858553872e-08 7.524525543906159 0.27424310673844143 TAPSAGMQPQPS(ph)LCSSAMR ddPTM_PC-9_AZD4547_30min_R2 2 TAPSAGMQPQPSLCSSAMR 19 0 Q13555-6;H0Y6G2;A0A2Q3DQE3;Q13555-3;Q13555-7;Q13555-9;Q13555-2;Q13555-8;Q13555 Q13555-6 CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 1 TAPSAGMQPQPS(0.994)LCS(0.005)S(0.002)AMR;TAPSAGMQPQPS(0.974)LCS(0.02)S(0.006)AMR 105.01 0.00014854 9410700.0 40287.0 46141.0 45967.0 60705.0 101957.0 69899.0 50525.0 57020.0 54337.0 54112.0 True False 53097.42797834334 61055.17591356671 45357.44754569578 46710.400132900686 87802.03045592568 65528.20448015799 55021.62712010564 48208.869189249555 57209.142888815906 52217.555350410956 1.0168501306127395 1.1692461568499337 0.8686244930717312 0.8945344112616155 1.6814657420616814 1.2549075505435794 1.0536997902501886 0.9232310640691483 1.095592133812248 1.0 15.672247296671749 -7.510763869431306 22.917067928500703 1.0033400113687567 1.1491401721991992 0.08166898287959579 0.21700561037022711 563.1442128309316 1065286.8407026771 0.10351095320239817 0.06556160795669998 3.08486476842343e-08 7.510763869431306 0.14580016083044245 TAPSAGMQPQPS(ph)LCSSAMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TAPSAGMQPQPSLCSSAMR 19 0 Q13555-6;H0Y6G2;A0A2Q3DQE3;Q13555-3;Q13555-7;Q13555-9;Q13555-2;Q13555-8;Q13555 Q13555-6 CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 1 TAPSAGMQPQPS(0.993)LCS(0.005)S(0.002)AMR;TAPSAGMQPQPS(0.994)LCS(0.005)S(0.001)AMR;TAPSAGMQPQPS(0.999)LCSSAMR 105.92 0.00013819 10506100.0 68902.0 51405.1 52954.1 65775.1 63017.0 56888.5 40640.7 48860.9 37208.0 33000.299999999996 True False 80565.74772346787 56508.2586035294 54216.7265735426 62089.93439275134 50669.2712213196 53905.166913519344 36790.918682812095 47578.353147402886 37752.096609379754 38982.99315976892 2.0666896303543214 1.4495618223037536 1.3907789571554792 1.5927441522584047 1.2997788808482542 1.3827867627453079 0.9437684410744764 1.2204899955323214 0.9684247808949809 1.0 15.250557246209185 -1.522878745290273 0.23981351645326646 0.9595863227275945 6.581096104371065 0.7638708673848088 0.15627174957171014 24.969284354895887 0.3334789851467848 0.21429000637650272 55.84843880479888 0.029999999999313683 1.522878745290273 5.6215097816434705 up TAPSAGMQPQPS(ph)LCSSAMR ddPTM_PC-9_Lapatinib_30min_R1 2 TAPSAGMQPQPSLCSSAMR 19 0 Q13555-6;H0Y6G2;A0A2Q3DQE3;Q13555-3;Q13555-7;Q13555-9;Q13555-2;Q13555-8;Q13555 Q13555-6 CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 1 TAPSAGMQPQPS(0.978)LCS(0.016)S(0.006)AMR;TAPSAGMQPQPS(0.956)LCS(0.032)S(0.011)AMR 88.471 0.0039657 2418800.0 16063.6 10430.3 24633.0 22465.7 16134.3 13256.5 12349.4 13122.9 20465.4 19344.5 True False 15834.530118296549 10406.149281185717 22607.769826129777 24117.90252137825 15185.31219525426 12689.550397410829 12988.791505921728 13732.637841501766 18160.371141784002 22688.171050073986 0.6979200784121782 0.4586596803338091 0.9964562492160889 1.0630166031518704 0.6693052587508918 0.5593024827521057 0.5724917833727003 0.6052774289824029 0.8004334550239025 1.0 14.469652694009758 -8.540704255161202 18.225813939906782 1.000000014912397 0.7060071007368889 0.202384051280049 0.17997353031358157 134.32113096842969 137340.5879427787 0.19140433682693492 0.04942038335760517 2.8793585260870814e-09 8.540704255161202 -0.2939929141755082 TAPSS(ph)PLTSPSDTR ddPTM_PC-9_AZD4547_30min_R2 1 TAPSSPLTSPSDTR 14 0 A0A087WVA8;Q8IWB9;Q8IWB9-2 A0A087WVA8 TEX2 Testis-expressed sequence 2 protein 1 TAPS(0.023)S(0.968)PLT(0.007)S(0.002)PSDTR 141.91 0.00014167 9397200.0 13592.0 12357.0 23029.0 28314.0 27398.0 25360.0 20649.0 26938.0 17021.0 21872.0 True False 17913.97326883714 16351.158595694582 22723.620413118708 21786.644746939302 23594.26062390474 23774.235191015687 22486.72099758656 22775.351073658436 17920.6953109398 21106.267937318687 0.8487513435363366 0.7747062931378579 1.076629012793888 1.032235770513347 1.117879328262812 1.126406395560803 1.0654048865658077 1.0790799747874227 0.8490698291218802 1.0 14.365383879867826 -5.263261191206603 24.958792241677013 1.0521829312842603 0.8117288046257146 0.5931646122511638 0.07644491115265907 94.2287458715462 1290954.0379522392 0.019922459843968288 0.04521063955837632 5.454297328193613e-06 5.263261191206603 -0.2404541266585457 TAPSS(ph)PLTSPSDTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TAPSSPLTSPSDTR 14 0 A0A087WVA8;Q8IWB9;Q8IWB9-2 A0A087WVA8 TEX2 Testis-expressed sequence 2 protein 1 T(0.022)APS(0.144)S(0.585)PLT(0.182)S(0.062)PS(0.005)DTR;TAPS(0.136)S(0.796)PLT(0.032)S(0.013)PS(0.022)DT(0.001)R;TAPS(0.152)S(0.828)PLT(0.015)S(0.002)PS(0.002)DTR;TAPS(0.145)S(0.798)PLT(0.043)S(0.008)PS(0.005)DT(0.001)R 140.33 0.00011671 27086100.0 74703.0 83262.0 107418.0 82648.0 126942.0 109796.0 81592.0 106386.0 84258.0 69989.0 True False 87348.74244849512 91527.70110061174 109979.25250503355 78017.50050843133 102068.62636077157 104038.10447518856 73863.0150850751 103593.48022528458 85490.1138495246 82677.45166738098 1.056500178548163 1.1070455033959696 1.3302206379980146 0.9436369764068555 1.2345400626449285 1.2583612868686793 0.8933876600627801 1.252983469326688 1.0340197009634406 1.0 16.33520630141041 -8.803322742896285 0.6778172965927433 0.9973133726362848 1.140330923581785 0.08711801906522199 0.13572508995926338 3.0589628399734528 2.823010817028711 0.13870053585952563 0.05129417241848711 1.5728136046643513e-09 8.803322742896285 0.14301755094550006 TAPSS(ph)PLTSPSDTR ddPTM_PC-9_Lapatinib_30min_R1 1 TAPSSPLTSPSDTR 14 0 A0A087WVA8;Q8IWB9;Q8IWB9-2 A0A087WVA8 TEX2 Testis-expressed sequence 2 protein 1 TAPS(0.008)S(0.85)PLT(0.142)SPS(0.001)DTR 226.23 1.8148e-20 9174500.0 57208.0 54443.0 52596.0 38141.0 44062.0 33642.0 29695.0 28071.0 49594.0 19483.0 True False 56392.20342933764 54316.940578467955 48271.759906431245 40946.01637464613 41470.359789225025 32203.21008333234 31232.461801249083 29375.281138223712 44008.20147202774 22850.610590534343 2.4678641827058048 2.3770454782056567 2.1124932182962053 1.7919003176049766 1.8148468998199874 1.4092931983477162 1.366810820109413 1.2855359388248537 1.9259092135707627 1.0 14.479945095562186 -5.679716692417215 0.656538828817078 1.3714653109284842 2.6863573405534082 0.7660430336779797 0.2225869915320094 0.6181223986523174 0.4207923051091087 0.12059810760606288 0.5238207261891739 2.0906595065531706e-06 5.679716692417215 1.314892029624924 TAPSSPLT(ph)SPSDTR ddPTM_PC-9_Lapatinib_30min_R1 1 TAPSSPLTSPSDTR 14 0 A0A087WVA8;Q8IWB9;Q8IWB9-2 A0A087WVA8 TEX2 Testis-expressed sequence 2 protein 1 T(0.001)APS(0.019)S(0.33)PLT(0.458)S(0.148)PS(0.043)DT(0.001)R 85.287 0.020884 0.0 18315.0 15117.0 20709.0 11161.0 12857.0 15255.0 8795.8 7669.9 15955.0 8962.3 True False 18053.82474144034 15081.997515285715 19006.385959051735 11981.817172004554 12100.776537834552 14602.579211141861 9251.203485820064 8026.271554346551 14157.979886401616 10511.421613485913 1.7175435830941934 1.4348199577434757 1.8081651234184135 1.1398855086006785 1.1512026615229223 1.3892106841578011 0.8801096393993922 0.7635762173262111 1.3469139006123827 1.0 13.359670178823814 -6.031532101616459 0.9260140609053289 1.0200518288587228 1.6793496070340943 0.5574505356706885 0.2154775683129614 0.47545875058627296 0.8315257900779233 0.09744081602898307 0.20913730941845102 9.299677720612855e-07 6.031532101616459 0.6592977781753715 TAPT(ph)LSPEHWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TAPTLSPEHWK 11 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 T(0.012)APT(0.66)LS(0.328)PEHWK 127.52 0.00087088 21608000.0 81457.0 77474.0 70884.0 77450.0 98165.0 93462.0 83510.0 83687.0 85727.0 94911.0 True False 95246.0612509147 85165.10671217118 72574.14338906694 73110.72759628783 78930.27293334872 88560.68818955217 75599.32823995728 81490.30492370616 86980.59519544999 112117.6129849376 0.8495191675522962 0.7596050651168667 0.647303679207092 0.6520895838739438 0.7039953030747504 0.7898909531854715 0.6742859237478918 0.7268287537895937 0.7757977794901446 1.0 16.774653408869447 -8.801912930167937 2.098682771748364 0.9999278581007823 0.7212506402341969 0.6546585322325194 0.059537278282011816 0.8228078502761201 5.266253555302571 0.06041104229971236 0.016610592335057513 1.5779275899026923e-09 8.801912930167937 -0.2786772178665854 TAPTALGIT(ph)LSSSPTSTPELR ddPTM_PC-9_AZD4547_30min_R2 1 TAPTALGITLSSSPTSTPELR 21 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 TAPTALGIT(0.393)LS(0.047)S(0.288)S(0.213)PT(0.044)S(0.011)T(0.002)PELR 99.941 0.00052392 20180000.0 36590.0 29708.0 38247.0 52200.0 43744.0 37416.0 38441.0 41485.0 34561.0 34947.0 True False 48224.85888072036 39310.53002839645 37739.819789854126 40166.096481960536 37670.90067640302 35076.371605167325 41862.17452991546 35074.44648046328 36387.82390232011 33723.51616703892 1.4300068427578418 1.1656711546234977 1.1190950434385816 1.1910411797812037 1.1170513919667202 1.040116084913194 1.2413348098864967 1.0400589993858573 1.0790044466918685 1.0 15.041467345612554 -1.9750277147363973 1.0941458509955246 1.1047861731305422 199.99999994242836 0.6726204362551255 0.06814153892370707 567.7248995998003 1.4936534712413312 0.02009627602076659 282368.220330235 0.0105918613048682 1.9750277147363973 198.8952137692978 TAPTALGITLSS(ph)SPTSTPELR ddPTM_PC-9_AZD4547_30min_R2 2 TAPTALGITLSSSPTSTPELR 21 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 TAPTALGIT(0.007)LS(0.005)S(0.46)S(0.46)PT(0.061)S(0.005)T(0.001)PELR;TAPTALGITLSS(0.607)S(0.39)PT(0.002)STPELR 206.63 1.4014e-24 41446000.0 27819.8 33440.0 36854.0 50845.0 46133.0 41952.0 39141.0 49404.0 32923.0 40873.0 True False 36665.917712212744 44248.826045158785 36365.29188002418 39123.47079741925 39728.229263544716 39328.73480810295 42624.47317383582 41769.74699098006 34663.24256636336 39442.048710772935 0.9296149391499043 1.1218693625585672 0.9219929762444519 0.9919228862656246 1.0072557223097192 0.9971270786793832 1.0806860841940407 1.059015653504108 0.8788398092743006 1.0 15.26744687011185 -5.293285385922201 24.998364337924166 0.9980903060840574 1.0257424345570125 0.030067738947412437 0.07010916584396817 2827.105144922405 2219205.563258665 0.017932405579578967 0.03733933756930041 5.089962867639461e-06 5.293285385922201 0.027652128472955173 TAPTALGITLSS(ph)SPTSTPELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TAPTALGITLSSSPTSTPELR 21 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 TAPTALGITLS(0.002)S(0.862)S(0.135)PT(0.001)STPELR;TAPTALGITLSS(0.793)S(0.194)PT(0.01)S(0.003)TPELR 289.61 2.3222999999999995e-186 25036000.0 31643.3 35754.2 38663.9 43437.1 44230.0 41177.0 41084.1 39290.5 35732.7 29273.0 True False 36999.885706336696 39303.6406847241 39585.79400965728 41003.46011197826 35563.44900771166 39017.60563203435 37192.31662487411 38259.166006725885 36255.223137873116 34579.96317505949 1.0699804831782629 1.136601577212538 1.1447610227129508 1.1857577726268853 1.0284409161361252 1.128329878042654 1.075545292994955 1.1063969563252742 1.048445973014277 1.0 15.077648712173735 -8.5781530888451 0.4496916120865094 0.9940798479267019 1.1266557367798582 0.43321449454410155 0.04140354538458889 1.219575559428922 0.6105162367633213 0.05687517953665751 0.027506509706610543 2.6414774721389182e-09 8.5781530888451 0.1325758888531563 TAPTALGITLSS(ph)SPTSTPELR ddPTM_PC-9_Lapatinib_30min_R1 1 TAPTALGITLSSSPTSTPELR 21 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 TAPTALGITLSS(0.609)S(0.384)PT(0.005)S(0.001)TPELR 216.34 5.5808e-32 21800000.0 29737.0 28723.0 27951.0 23266.0 28021.0 25907.0 21487.0 22232.0 29480.0 23346.0 True False 29312.9449269021 28656.493658235846 25652.97667398017 24977.059253100793 26372.859871405624 24799.01800216665 22599.49172330154 23264.979881906245 26159.651961837662 27381.32499341039 1.070545159299507 1.0465707435681924 0.9368785725363485 0.9121932287466654 0.9631696010968255 0.905690941111681 0.8253615093038905 0.8496659634807743 0.9553829834068754 1.0 14.740904640432005 -5.263567284817306 1.9996612200882702 0.9064056459335181 1.0774831604277437 0.5635626102783005 0.04926338971048463 0.2691441485211405 1.9369905206204605 0.014494675077791029 0.057588173440268196 5.450454457919022e-06 5.263567284817306 0.1710775144942256 TAPTALGITLSSS(ph)PTSTPELR ddPTM_PC-9_AZD4547_30min_R2 1 TAPTALGITLSSSPTSTPELR 21 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 TAPTALGITLSS(0.027)S(0.967)PT(0.005)S(0.001)TPELR 248.94 1.6477999999999998e-61 15408000.0 31803.0 23828.0 36240.0 47929.0 30890.0 35061.0 36949.0 36622.0 31697.0 34484.0 True False 41915.692456505865 31529.935018063505 35759.43392120467 36879.70954566833 26601.456700212348 32868.63012745274 40237.389420302476 30962.91138984034 33372.43870929197 33276.72565611272 1.2596098813828525 0.9475071358852778 1.0746079494343486 1.1082733898397772 0.799401268475639 0.9877363075659154 1.209175140490757 0.9304674897950079 1.0028762761747765 1.0 15.022225862544996 -4.7527072720074255 24.945540093751237 1.009056137281893 1.259610370068665 0.3461171251837979 0.10425118617081808 394.6104924218469 1127220.7898964433 0.02630787290462175 0.3041425819854924 1.7672285863837643e-05 4.7527072720074255 0.250554232786772 TAPTALGITLSSS(ph)PTSTPELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TAPTALGITLSSSPTSTPELR 21 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 TAPTALGITLS(0.001)S(0.099)S(0.889)PT(0.008)S(0.002)T(0.001)PELR;TAPTALGITLS(0.002)S(0.216)S(0.591)PT(0.139)S(0.044)T(0.007)PELR;TAPTALGITLSS(0.03)S(0.8)PT(0.166)S(0.003)T(0.001)PELR;TAPTALGITLSS(0.027)S(0.937)PT(0.032)S(0.003)TPELR 261.06 9.496399999999996e-74 45198600.0 132156.8 119018.5 148295.9 147911.2 175034.0 163354.5 167913.4 160296.3 138624.7 117963.3 True False 154528.33602421955 130833.87011413548 151831.83667133262 139624.21499858025 140737.34419208227 154787.90245083775 152007.42716425908 156088.69197296913 140651.82398533353 139349.11249303116 1.1089294596831214 0.9388927404950532 1.0895787849307308 1.0019741963233735 1.009962257198592 1.1107921656736686 1.090838861078939 1.1201269185031595 1.0093485453118154 1.0 17.088344288461023 -6.747195358055622 24.989255594899582 1.0752678338226216 1.0265809994822586 0.07959830542832114 0.05731341518077268 453.54609071265526 795685.8356070983 0.017840233302630976 0.017764897214383252 1.7898005695398676e-07 6.747195358055622 -0.04868683434036303 TAPTALGITLSSS(ph)PTSTPELR ddPTM_PC-9_Lapatinib_30min_R1 3 TAPTALGITLSSSPTSTPELR 21 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 TAPTALGITLS(0.002)S(0.208)S(0.739)PT(0.037)S(0.011)T(0.003)PELR;TAPTALGITLSS(0.404)S(0.586)PT(0.007)S(0.002)TPELR;TAPTALGITLSS(0.228)S(0.765)PT(0.005)S(0.001)TPELR 171.29 6.3763e-09 31297800.0 70273.0 54729.0 73557.0 54418.0 61538.0 60270.0 49467.0 44502.0 62871.0 51870.0 True False 69270.89413351013 54602.27836303976 67509.42739823114 58420.081253126395 57918.45582836297 57692.3925962321 52028.15921611012 46569.72538253829 55789.805919019505 60835.66038756952 1.1386560726422914 0.8975373656697673 1.109701562671378 0.9602933687404057 0.9520477867648393 0.94833182098604 0.8552246969072267 0.7655004496680671 0.9170576198827451 1.0 15.892629623988794 -6.549386186516056 1.1844036348525016 0.8697785082542192 1.0321798868147904 0.35373101777560934 0.0844570531100482 0.47772339054781904 1.4111018102703528 0.037717009172354383 0.04170779544612832 2.8223691310014e-07 6.549386186516056 0.16240137856057124 TAPTALGITLSSSPT(ph)STPELR ddPTM_PC-9_Lapatinib_30min_R1 1 TAPTALGITLSSSPTSTPELR 21 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 TAPTALGITLSS(0.232)S(0.069)PT(0.628)S(0.069)T(0.001)PELR 202.84 3.4996000000000003e-20 10772000.0 21935.0 20226.0 22182.0 20253.0 23596.0 19107.0 18535.0 18306.0 26501.0 16737.0 True False 21622.202877613665 20179.16793968173 20358.281584996177 21742.473182027446 22208.12967152089 18289.838150592444 19494.651607548487 19156.563589338584 23516.17831209836 19629.96814934934 1.1014894529174444 1.0279776200426791 1.0371021200903465 1.1076163250294488 1.131338038989992 0.9317304038111077 0.9931066346735087 0.9758835798199474 1.1979733300218234 1.0 14.260770211507225 -6.7420696622813825 24.999905445829665 1.016566951588473 1.0771814623522922 0.153887835036574 0.07145837412319356 500.8545436490323 646436.5886384186 0.023910555903932686 0.02387812803242795 1.8110495709367426e-07 6.7420696622813825 0.060614510763819185 TAPTLS(ph)PEHWK ddPTM_PC-9_AZD4547_30min_R2 6 TAPTLSPEHWK 11 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 T(0.002)APT(0.123)LS(0.875)PEHWK;T(0.009)APT(0.404)LS(0.586)PEHWK;TAPT(0.13)LS(0.869)PEHWK;TAPT(0.086)LS(0.914)PEHWK;TAPT(0.121)LS(0.879)PEHWK;TAPT(0.002)LS(0.998)PEHWK 160.18 0.00052274 199710700.0 314167.0 253144.0 362897.0 489859.0 440130.0 356476.0 332636.0 423762.0 346167.0 401532.0 True False 414065.57092045085 334967.8474992725 358084.74866731284 376929.57579610584 379025.54669681017 334185.4993672131 362239.9595986832 358279.3199820204 364464.680906063 387474.48689682945 1.0686266707172947 0.8644900730934123 0.9241505202964704 0.9727855343840192 0.9781948476977558 0.8624709772341598 0.9348743513405432 0.9246526728801562 0.94061594564575 1.0 18.563741794270946 TAPTLS(ph)PEHWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TAPTLSPEHWK 11 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 TAPT(0.082)LS(0.918)PEHWK;T(0.043)APT(0.025)LS(0.932)PEHWK;TAPT(0.022)LS(0.978)PEHWK;TAPT(0.03)LS(0.969)PEHWK;T(0.002)APT(0.081)LS(0.917)PEHWK 131.06 0.00017779 129434000.0 220255.0 217674.0 253554.0 313059.0 318122.0 305740.0 284889.0 296171.0 275595.0 221900.0 True False 257539.82126545606 239283.23616264993 259599.68896889995 295519.3191809726 255788.2777578849 289706.4561754907 257902.2515022536 288396.8250691137 279625.0555004838 262128.71344056627 0.9824937447146527 0.9128463380525605 0.990351974652179 1.1273824805460586 0.9758117468343698 1.1052068747942687 0.983876386974787 1.1002107372510463 1.0667471404802227 1.0 17.999915868810533 -5.5298590786855595 24.653964112857622 1.0523287166530226 0.9486523082276498 0.4032312384166663 0.051609998008186816 117.32332591189628 414374.93099467066 0.012894735898931687 0.02240086881091518 2.9521670002104835e-06 5.5298590786855595 -0.10367640842537285 TAPTLS(ph)PEHWK ddPTM_PC-9_Lapatinib_30min_R1 5 TAPTLSPEHWK 11 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 T(0.001)APT(0.055)LS(0.944)PEHWK;TAPT(0.035)LS(0.965)PEHWK;T(0.007)APT(0.367)LS(0.626)PEHWK;T(0.197)APT(0.226)LS(0.576)PEHWK;TAPTLS(1)PEHWK 155.86 0.00019969 179354100.0 376541.0 347810.0 425221.0 358702.0 396411.0 409335.0 346020.0 336202.0 401242.0 298785.0 True False 371171.45629083813 347004.6673143835 390260.9707805275 385082.1416747947 373094.8843540123 391828.6962564905 363935.2225111372 351823.17228574253 356049.9006944257 350429.5891440124 1.0591898281120937 0.9902265050220361 1.1136644360820398 1.0988859206079813 1.064678599958879 1.118138160689007 1.0385402197346254 1.0039767850230175 1.0160383475725947 1.0 18.418765071034166 -7.520594992785463 5.761687040808414 1.009470003664707 1.073351200541971 0.4418033249675001 0.03412354981332064 0.1664029037187404 20.87874501319317 0.016590868407861926 0.01007734234238075 3.015817154429879e-08 7.520594992785463 0.0638811968772639 TAPTSTIAPGVVMASS(ph)PALPTQPAEEAAR ddPTM_PC-9_AZD4547_30min_R2 1 TAPTSTIAPGVVMASSPALPTQPAEEAAR 29 0 C9JBT4;C9J896;P16220;P16220-1;H7C1R5 C9JBT4 CREB1 Cyclic AMP-responsive element-binding protein 1 1 TAPTSTIAPGVVMAS(0.216)S(0.76)PALPT(0.024)QPAEEAAR 86.009 3.5424e-08 5392400.0 11228.0 13449.0 19610.0 23247.0 24659.0 20522.0 11922.0 18894.0 20319.0 17509.0 True False 14798.270443091791 17796.126240470716 19349.95858705362 17887.76331256967 21235.52349532328 19238.75609582113 12983.034904025708 15974.366440927404 21393.020857939347 16896.015239324825 0.8758438148569722 1.0532735670746152 1.1452379932765058 1.0586971578326108 1.2568361944832067 1.1386564123737095 0.7684080962360992 0.9454517064915804 1.2661577629350094 1.0 14.044395420594748 TAQALS(ph)SGSGSQETK ddPTM_PC-9_AZD4547_30min_R2 1 TAQALSSGSGSQETK 15 0 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 TAQALS(0.958)S(0.038)GS(0.002)GS(0.002)QETK 106.38 0.0042976 0.0 4009.7 2417.1 5243.4 6304.8 8805.9 5389.4 6452.2 6502.3 4846.3 3843.1 True False 5284.701193058879 3198.380306033292 5173.8690900233005 4851.325768188981 7583.352785898345 5052.3999660275995 7026.433300432366 5497.518942989427 5102.465524082457 3708.5542387485984 1.425003074740557 0.862433201762351 1.3951175463377212 1.3081447528797625 2.0448272555013904 1.3623637786493488 1.8946556658163751 1.482388712439188 1.3758637990971423 1.0 11.856641153690708 -5.742282931369847 2.446922263025514 1.5613193417994917 1.1551272390631457 0.14686575662019785 0.30981130639413307 0.40973427450006766 4.997550892580444 0.08656104754351392 0.16194606267413258 1.8101604367499866e-06 5.742282931369847 -0.406192102736346 TAQALSS(ph)GSGSQETK ddPTM_PC-9_AZD4547_30min_R2 1 TAQALSSGSGSQETK 15 0 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 TAQALS(0.005)S(0.439)GS(0.439)GS(0.117)QETK 108.77 0.00070052 3427000.0 14202.0 12719.0 14718.0 18656.0 17150.0 17808.0 20663.0 22559.0 20794.0 19181.0 True False 18717.940580048933 16830.168016398762 14522.829703429645 14355.147432326752 14769.018530548445 16694.462944858347 22501.966970464953 19073.024904249032 21893.128388207635 18509.47902824201 1.0112624213511816 0.9092729185256412 0.7846158004377388 0.7755565356768538 0.7979164896004732 0.9019412658446903 1.2156996388786065 1.0304463391512617 1.1828062991293709 1.0 14.175976668926008 -7.121707580173919 5.467678621706527 1.108441925065504 0.8503468200999779 0.6505059734097202 0.08792512060951893 0.1446052563959184 5.875418186145236 0.03482374453252022 0.026898760519711722 7.556008187247321e-08 7.121707580173919 -0.2580951049655261 TAQALSS(ph)GSGSQETK ddPTM_PC-9_Lapatinib_30min_R1 1 TAQALSSGSGSQETK 15 0 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 TAQALS(0.124)S(0.414)GS(0.414)GS(0.037)QET(0.011)K 186.17 3.8713e-07 6011200.0 14216.0 18982.0 17484.0 20568.0 20226.0 17928.0 17000.0 16255.0 16648.0 20835.0 True False 14013.277233104885 18938.048345250598 16046.533010191732 22080.639332836632 19036.34644584597 17161.26123220921 17880.176818361157 17010.266641794977 14772.926928788109 24436.301989107586 0.5734614525287527 0.7749964930737957 0.6566678140311258 0.9035998713176411 0.7790191189457132 0.702285527485247 0.7317055103645059 0.6961064177950189 0.6045483860599324 1.0 14.576738354327905 -11.67819022519744 2.527490044463705 1.689216570029248 0.7209280167774319 0.47776243992772494 0.08953590067658815 7655840.946060947 1547405.4254672274 30485993.437136155 0.02283055770239887 2.098020728900555e-12 11.67819022519744 -0.9682885532518162 TAQALSSGS(ph)GSQETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TAQALSSGSGSQETK 15 0 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 TAQALS(0.039)S(0.019)GS(0.94)GS(0.002)QETK 191.93 1.5083e-38 0.0 8499.2 8649.3 10129.0 10761.0 13269.0 12374.0 11349.0 10605.0 9877.3 8945.1 True False 9937.946693148213 9507.94534276767 10370.513774446414 10158.096057632718 10669.034702313502 11725.085656817957 10273.940560355368 10326.629986926304 10021.736826484255 10566.775820627363 0.9404899717611482 0.8997962580229295 0.9814264966426347 0.9613240812588394 1.0096773967217625 1.1096180950417687 0.9722871701602345 0.9772734997148069 0.9484195554637264 1.0 13.367247622195919 -5.583001027191795 1.6816882770727455 1.0029647729339144 0.9200983968259238 0.32154963452230334 0.04318660973589821 0.48057434752615685 2.661830548732906 0.014221879548456754 0.038322079439227774 2.6121551761315817e-06 5.583001027191795 -0.08286637610799064 TAQALSSGS(ph)GSQETK ddPTM_PC-9_Lapatinib_30min_R1 1 TAQALSSGSGSQETK 15 0 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 TAQALS(0.041)S(0.008)GS(0.951)GSQETK 216.29 9.458e-18 4654800.0 12560.0 15107.0 15921.0 18296.0 18959.0 13134.0 14919.0 15579.0 19671.0 17507.0 True False 12380.892096778096 15072.020669671314 14612.036836837264 19641.5488736668 17843.868894828138 12572.289436849382 15691.43282077237 16302.857213935635 17455.44483518686 20533.06162338884 0.6029735031172967 0.7340366938997079 0.7116345874203658 0.9565815967402284 0.8690310885982298 0.6122949254936494 0.7642032692727393 0.7939808253127407 0.850114082125175 1.0 14.325661138976567 -14.522878745280131 0.12352852326164022 1.7508617365613306 0.66354989052854 0.38530682897326785 0.09861844739607581 187.4350792190251 1.4815019014106012 35.10844254493273 0.9511920245064802 3.0000000000014245e-15 14.522878745280131 -1.0873118460327906 TAQALSSGSGS(ph)QETK ddPTM_PC-9_AZD4547_30min_R2 3 TAQALSSGSGSQETK 15 0 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 TAQALSSGS(0.004)GS(0.551)QET(0.445)K;TAQALS(0.001)S(0.007)GS(0.38)GS(0.611)QETK;TAQALS(0.001)S(0.008)GS(0.027)GS(0.962)QET(0.002)K 220.78 2.9687000000000002e-18 20526000.0 44654.0 52145.0 51938.0 52555.0 55344.0 57248.0 60508.0 62691.0 57184.0 55053.0 True False 58853.0431391005 68999.85149894744 51249.268184313674 40439.256716655866 47660.44090697802 53668.2735100657 65893.09478047199 53003.54644586534 60206.62949655023 53125.61122682902 1.1078092426610813 1.2988057907576929 0.9646810079134153 0.7612007802412557 0.8971273893392679 1.0102147019244576 1.24032633712448 0.9977023364410339 1.1332882221248726 1.0 15.69711991444183 -5.2726624804923 24.443137777096073 0.9971497737680081 1.2033075200074146 0.2874175138140379 0.12760020560334495 648.235772336935 1411814.804853944 0.03675848451102996 0.0777056392184 5.337495470807337e-06 5.2726624804923 0.20615774623940653 TAQALSSGSGS(ph)QETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TAQALSSGSGSQETK 15 0 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 TAQALSSGS(0.005)GS(0.988)QET(0.007)K;TAQALS(0.002)S(0.001)GS(0.005)GS(0.992)QETK 216.71 8.852599999999999e-18 8036500.0 40173.0 45734.0 36242.0 35172.0 41852.0 29416.0 37897.0 30220.0 29203.0 26132.0 True False 46973.49544708249 50274.1692745236 37106.146728550375 33201.42686916255 33651.40103709581 27873.373176091547 34307.1218094799 29426.75702073673 29630.038628351864 30869.52473920181 1.5216786083988503 1.6286019852673486 1.2020316814734942 1.075540590587694 1.0901172376768484 0.9029414418128248 1.1113589243540447 0.9532623929051658 0.9598475803783303 1.0 14.913895651239942 -5.452337437944957 2.166409161816824 1.0094858825200221 1.5913610477371132 0.9082657847561616 0.07029338113908717 0.08367808708249022 0.7565986994959608 0.019714000833444115 0.0536831610830822 3.529088602606217e-06 5.452337437944957 0.581875165217091 TAQALSSGSGS(ph)QETK ddPTM_PC-9_Lapatinib_30min_R1 2 TAQALSSGSGSQETK 15 0 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 TAQALSSGS(0.008)GS(0.99)QET(0.001)K;TAQALS(0.005)S(0.059)GS(0.205)GS(0.723)QET(0.008)K 210.2 2.8069e-13 9037300.0 28918.0 38242.0 36811.0 34711.0 44141.0 44698.0 41121.0 38363.0 41537.0 36849.0 True False 28505.624017088285 38153.452998581466 33784.541674569205 37263.76273250158 41544.71316454503 42786.370736127144 43250.044173401715 40145.48503101695 36858.66565599902 43218.300551793865 0.659572996928152 0.8828078039037522 0.7817184212063356 0.8622218425234879 0.9612759556511675 0.9900058583944298 1.0007344949061523 0.9289001306959218 0.8528485661259794 1.0 15.399354722600556 -6.009095431307496 2.258785388971564 0.9567166129995136 0.7817652397175847 0.611134803304386 0.06478788610152902 0.21936135252399722 2.2423501656577183 0.020508678505442638 0.03153195651298167 9.79274777192375e-07 6.009095431307496 -0.1749513732819289 TAQDLSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 TAQDLSSPR 9 0 Q9UHI6;Q9UHI6-2 Q9UHI6 DDX20 Probable ATP-dependent RNA helicase DDX20 1 TAQDLS(0.027)S(0.973)PR;TAQDLS(0.136)S(0.864)PR 90.913 0.008206399999999999 13305600.0 112387.0 94665.0 105076.0 88100.0 82117.0 89818.0 73785.0 66613.0 97169.0 65582.0 True False 110784.3407707486 94445.80900870045 96437.05688508948 94579.16789298445 77287.03950823369 85976.69351598427 77605.22626722232 69708.0831627122 86224.8039850679 76917.76131747784 1.4402959586081368 1.2278803671739178 1.2537683785029285 1.229614152479155 1.0048009482391416 1.117774257120091 1.008937661964796 0.9062677068173147 1.120999916120482 1.0 16.231029153366457 -5.277182211358429 0.5159166062237432 0.9918457922465721 1.5442596183806483 0.7637023946905913 0.07349870620574384 1.3044465483405119 0.38346759251176316 0.048083787401547465 0.4104701206913056 5.282235852914806e-06 5.277182211358429 0.5524138261340762 TAQDPGIS(ph)PSQSLCAESSR ddPTM_PC-9_AZD4547_30min_R2 1 TAQDPGISPSQSLCAESSR 19 0 A0A0A0MT72;Q9BSQ5-4;Q9BSQ5;Q9BSQ5-2;A0A3B3IRS0;E9PEC4 A0A0A0MT72 CCM2 Cerebral cavernous malformations 2 protein 1 TAQDPGIS(0.46)PS(0.46)QS(0.081)LCAESSR 240.94 3.6696999999999996e-44 8616300.0 18152.0 20957.0 25121.0 34713.0 27120.0 22469.0 18655.0 24732.0 21866.0 21606.0 True False 23923.95841494495 27730.94041352848 24787.879126230193 26710.45416050377 23354.85612527544 21064.00987803359 20315.258860476395 20910.237684821448 23021.792119676258 20849.58051635459 1.1474551440581164 1.3300478823435364 1.1888910238163481 1.2811027128124646 1.1201595210491497 1.0102845887719805 0.9743725464663874 1.0029092752450957 1.1041849068194811 1.0 14.347730737173203 -6.5183186432554345 3.167480988489878 1.0162588719986843 1.2395460306533168 0.7699695318276254 0.05614043437368729 0.1118914910116938 2.318271798367795 0.018386149065422252 0.019623979930734295 3.0316660248968784e-07 6.5183186432554345 0.22328715865463256 TAQDPGIS(ph)PSQSLCAESSR ddPTM_PC-9_Lapatinib_30min_R1 1 TAQDPGISPSQSLCAESSR 19 0 A0A0A0MT72;Q9BSQ5-4;Q9BSQ5;Q9BSQ5-2;A0A3B3IRS0;E9PEC4 A0A0A0MT72 CCM2 Cerebral cavernous malformations 2 protein 1 TAQDPGIS(0.487)PS(0.487)QS(0.026)LCAESSR 160.05 1.8901e-20 0.0 21101.0 17829.0 18302.0 16000.0 15186.0 16833.0 16569.0 16719.0 19537.0 13498.0 True False 20800.095870550518 17787.71804591049 16797.280207763037 17176.69337443534 14292.789336824733 16113.091829639534 17426.861747260347 17495.825775710255 17336.53732626941 15831.111315045546 1.313874652045593 1.123592506674211 1.0610297580182677 1.0849960582433011 0.9028291856706974 1.0178117953302495 1.1007983836673698 1.1051546178620195 1.095092882695679 1.0 13.95047491313129 -4.584490734320765 1.5506720166989159 1.0449278630121195 1.5313022349818133 0.6613025245931713 0.05817729017666517 1.2055779391066905 1.8926822540786703 0.017843071287837162 1.033611497072721 2.603210370313714e-05 4.584490734320765 0.4863743719696938 TAQDPGISPS(ph)QSLCAESSR ddPTM_PC-9_AZD4547_30min_R2 1 TAQDPGISPSQSLCAESSR 19 0 A0A0A0MT72;Q9BSQ5-4;Q9BSQ5;Q9BSQ5-2;A0A3B3IRS0;E9PEC4 A0A0A0MT72 CCM2 Cerebral cavernous malformations 2 protein 1 TAQDPGIS(0.264)PS(0.704)QS(0.031)LCAESSR 161.1 5.1372000000000006e-06 9288400.0 28252.0 22156.0 37293.0 51540.0 58087.0 41057.0 36335.0 50161.0 40253.0 44448.0 True False 37235.54832189429 29317.493715805558 36798.47045318669 39658.24928506222 50022.622704604546 38489.6992995872 39568.744609778085 42409.77003510953 42380.69140187176 42891.889048918245 0.8681256327840238 0.6835206927437709 0.8579354108469784 0.9246095279187155 1.1662489998412915 0.8973654495769504 0.9225227773169395 0.9887596693804077 0.9880817175838661 1.0 15.388417236243157 -5.705133748693851 2.8846526847558893 0.9877724921527549 0.7764503312095564 0.53341188231061 0.08037728000494906 0.1922870700798882 3.2387337713172046 0.023054329486413342 0.04258280424085007 1.9718153870521517e-06 5.705133748693851 -0.21132216094319844 TAQDPGISPS(ph)QSLCAESSR ddPTM_PC-9_Lapatinib_30min_R1 1 TAQDPGISPSQSLCAESSR 19 0 A0A0A0MT72;Q9BSQ5-4;Q9BSQ5;Q9BSQ5-2;A0A3B3IRS0;E9PEC4 A0A0A0MT72 CCM2 Cerebral cavernous malformations 2 protein 1 TAQDPGIS(0.428)PS(0.557)QS(0.015)LCAESSR 197.0 6.337399999999999e-59 0.0 24801.0 20259.0 23550.0 19331.0 18136.0 18116.0 16672.0 17541.0 22089.0 16945.0 True False 24447.333192053607 20212.091530209247 21613.809905628874 20752.666226325586 17069.276136747885 17341.22091045861 17535.19458327748 18356.018896568796 19601.104212518054 19873.920672206754 1.2301213029516955 1.0170158099944224 1.087546350924874 1.0442160139719052 0.8588781458013414 0.8725616448046878 0.8823218564920644 0.9236234359252168 0.9862726402007719 1.0 14.278588891109349 -6.08089401792129 3.920273412269805 0.9129447872967016 1.098835723415502 0.6353590371190396 0.06557908995704848 0.1505887507575029 4.32675891916628 0.019686774246088435 0.026680364717317925 8.30053302994735e-07 6.08089401792129 0.18589093611880037 TAQEVETYRR ddPTM_PC-9_AZD4547_30min_R2 1 TAQEVETYRR 10 1 P17844-2;P17844;J3KTA4;J3QRQ7;J3QR02;J3KRX8;J3KTQ4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 100.69 0.0024625999999999997 4597700.0 23945.0 15297.0 28277.0 58712.0 36537.0 32474.0 24006.0 37757.0 25580.0 27054.0 False True 31559.011913059567 20241.456100861054 27902.028504136433 45176.85549135764 31464.468224527624 30443.3956464134 26142.487494215835 31922.523219545685 26932.106577394978 26106.8476945967 1.2088403886307304 0.7753312976599009 1.0687628330520837 1.7304599934793288 1.20521897521315 1.166107681882797 1.0013651513976738 1.2227643717457564 1.0316108207491124 1.0 14.672140647620441 -8.276783127871838 0.9432434684975021 1.0008695492372892 1.1814281952769048 0.06669703842401797 0.22734254793827918 1.9029567677776644 3.562785281645493 0.23335281874688485 0.08269450914959821 5.287092055458875e-09 8.276783127871838 0.18055864603961558 TAQEVETYRR ddPTM_PC-9_Lapatinib_30min_R1 2 TAQEVETYRR 10 1 P17844-2;P17844;J3KTA4;J3QRQ7;J3QR02;J3KRX8;J3KTQ4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 ; 151.79 0.00010566 12745200.0 116030.0 84462.0 95630.0 82089.0 86815.0 92731.0 68140.0 64057.0 105074.0 67266.0 False True 114375.39092270381 84266.43342832968 87767.67054247535 88126.09890087637 81708.71238485706 88765.11129651887 71667.95578841945 67033.32207157566 93239.45964172768 78892.83847368891 1.4497563167390468 1.068112582315477 1.1124922393525774 1.117035469959251 1.0356923893935854 1.1251352215717576 0.9084215649348326 0.8496756279586968 1.1818494738635044 1.0 16.26760672456105 -1.8139930702920433 0.9929359907734218 1.0239717020317523 199.99999999933078 0.6005244667062083 0.09838715286147537 579.8333085753834 1.59486289949374 0.03214355056091922 261373.28868255092 0.015346414697149766 1.8139930702920433 198.97602829729902 TAQSPAMVGS(ph)PIR ddPTM_PC-9_AZD4547_30min_R2 1 TAQSPAMVGSPIR 13 0 Q5VWG9 Q5VWG9 TAF3 Transcription initiation factor TFIID subunit 3 1 TAQS(0.139)PAMVGS(0.86)PIR 64.53399999999999 0.036839 7188000.0 27252.0 28879.0 37253.0 45541.0 44197.0 40923.0 33397.0 41551.0 36458.0 38222.0 True False 35917.56912318645 38213.57199037501 36759.00087932219 35042.22605143614 38061.0094457522 38364.07834077033 36369.26830143826 35130.24769699241 38385.09544951786 36883.85941387136 0.9738018117940904 1.0360513405493452 0.996614819150346 0.950069396432451 1.0319150449705417 1.0401318883224646 0.9860483387419167 0.9524558507502757 1.0407017069119917 1.0 15.17070200239739 TAQVPS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 4 TAQVPSPPR 9 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-3;Q9UKV3-2;G3V3B0;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 TAQVPS(1)PPR;TAQVPS(1)PPR;TAQVPS(1)PPR;TAQVPS(1)PPR 111.5 0.002231 826720000.0 1362070.0 1587600.0 1747700.0 2268720.0 2046510.0 2147530.0 1752920.0 2250520.0 1901770.0 1791320.0 True False 1795179.9271840057 2100760.6527898964 1724524.356073107 1745701.6553745903 1762387.4118339808 2013244.6096120607 1908926.4841440003 1902753.8458048026 2002293.6796595962 1728606.4320353726 1.038512812352691 1.215291470549676 0.9976385162714806 1.0098895983622418 1.0195423198552098 1.1646633798773598 1.1043152731395933 1.1007443976500642 1.1583282594303241 1.0 20.72117800384288 -6.7525445557668515 24.999872562623082 1.1118258535609282 1.0591913266004755 0.10465947196379577 0.07086947624349794 453.0327550343552 1273296.5811025482 0.023910015112489042 0.023568745931451564 1.7678908344198012e-07 6.7525445557668515 -0.05263452696045268 TAQVPS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TAQVPSPPR 9 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-3;Q9UKV3-2;G3V3B0;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 T(0.001)AQVPS(0.999)PPR;TAQVPS(1)PPR;TAQVPS(1)PPR;TAQVPS(1)PPR 98.182 0.0045443 567734000.0 1099891.0 1358759.0 1312677.0 1364597.0 1399351.0 1122243.0 1270469.0 1040281.0 987010.0 1100379.0 True False 1286080.8224625217 1493647.6137946013 1343976.1980352441 1288143.0541731622 1125158.2168752057 1063390.6014841078 1150120.9789209727 1012974.7260188307 1001443.1540105345 1299869.0021046281 0.9893926390891837 1.1490754925121105 1.033932031504099 0.990979131041297 0.8655935444675219 0.8180752058571776 0.884797604265355 0.7792898548843886 0.7704185209348712 1.0 20.309934808318907 -6.11943979565668 1.9247506984867933 0.8373150118537578 1.0696561247985168 0.6330694244778441 0.07110930260971866 0.19476882782330932 1.4270142661837286 0.022833792089703625 0.03330582562360277 7.595567093923762e-07 6.11943979565668 0.232341112944759 TAQVPS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 4 TAQVPSPPR 9 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-3;Q9UKV3-2;G3V3B0;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 TAQVPS(1)PPR;TAQVPS(1)PPR;TAQVPS(1)PPR;TAQVPS(1)PPR 112.64 0.0021543000000000005 802580000.0 1745060.0 2046400.0 1890090.0 1899930.0 2077290.0 2091190.0 1931750.0 2052000.0 1984760.0 1688500.0 True False 1720175.1243951926 2041661.6865304448 1734694.0961583937 2039657.1901806884 1955107.8863092754 2001754.6785019862 2031766.562874655 2147343.411194298 1761215.4283506398 1980354.9752151766 0.8686195888735988 1.0309574354509887 0.8759510885011459 1.029945245023089 0.9872512306016461 1.0108059936499436 1.0259607940510223 1.0843224765605355 0.8893432997583042 1.0 20.91732762340756 -5.781644830930269 24.999675458688746 1.0079678238314367 0.9357541444838591 0.24699446159102711 0.06193255850201412 332.4756613520291 411362.42537052534 0.016455152591357325 0.024440436572126988 1.6533133367338545e-06 5.781644830930269 -0.07221367934757761 TAS(ph)APNLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASAPNLDR 9 0 Q86W92-2 Q86W92-2 PPFIBP1 Liprin-beta-1 1 TAS(1)APNLDR 92.866 0.0066979 8780100.0 18251.0 17028.0 17917.0 21571.0 25790.0 24595.0 17905.0 24950.0 21640.0 15743.0 True False 21340.533826318726 18718.42730586846 18344.2092306009 20362.44680412558 20736.634635064052 23305.194902977008 16208.90877902572 24295.08893671017 21956.444061142156 18597.08127848056 1.1475205978162135 1.0065250038740388 0.9864025948968524 1.0949270210314022 1.1150478037141913 1.2531641150562909 0.8715834778751926 1.3063925770342795 1.1806392482969277 1.0 14.182788594674218 -5.979042871553417 5.82411631341222 1.1286280144655436 1.0419062064227211 0.06682313434004494 0.12171099586565644 0.42527724974497366 47.15266484666218 0.034298000490548514 0.05002286318289962 1.049438827765445e-06 5.979042871553417 -0.08672180804282248 TAS(ph)EGDGGAAAGAAAAGAR ddPTM_PC-9_AZD4547_30min_R2 2 TASEGDGGAAAGAAAAGAR 19 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 T(0.019)AS(0.981)EGDGGAAAGAAAAGAR;T(0.049)AS(0.951)EGDGGAAAGAAAAGAR 216.77 8.296099999999999e-28 95880000.0 21557.4 17793.7 28922.3 31657.0 27905.2 27275.0 23435.1 31620.0 23372.0 24129.5 True False 28412.204778224695 23545.165550231523 28538.771404504892 24358.967745774422 24031.04465881402 25569.489938286788 25520.778500195695 26733.855555315167 24607.396205116318 23284.7335494482 1.2202074255171371 1.0111846674229816 1.2256430310400181 1.046134699976057 1.0320515202710363 1.0981225052022436 1.0960305148435114 1.1481280427170146 1.0568038561772362 1.0 14.507096752835492 -10.089199530219297 0.012591873590880834 1.5153043578828922e-07 2.092301121072792 0.20677486441982385 0.06864949615434493 5149.239142456915 14.73340197290354 1300.9919625391706 1148.7475079235928 8.143300660777804e-11 10.089199530219297 2.0923009695423564 TAS(ph)EGDGGAAAGAAAAGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TASEGDGGAAAGAAAAGAR 19 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 T(0.01)AS(0.99)EGDGGAAAGAAAAGAR;T(0.226)AS(0.774)EGDGGAAAGAAAAGAR;T(0.03)AS(0.97)EGDGGAAAGAAAAGAR 239.7 6.2802e-44 30941000.0 82266.3 94132.0 116725.0 131503.0 158049.0 150465.0 167978.0 145413.0 152444.0 130131.0 True False 96192.35975651092 103476.80286328468 119508.16668202747 124135.31324847844 127080.43301423962 142574.350521506 152065.9077845954 141596.06282780928 154673.20510428658 153722.72018357075 0.6257523913292784 0.6731392909240481 0.7774268275978635 0.8075274305596468 0.8266860803821597 0.9274774109594749 0.9892220720723855 0.9211134350128581 1.0061831128123466 1.0 17.22997088522824 -5.432297377899099 0.4175732201926532 1.0084866411689617 0.4682866170652307 0.9547231328837095 0.027433371466203817 0.6299755230773061 0.12860015469784983 0.02417262465440267 0.16117981087205838 3.6957503108277585e-06 5.432297377899099 -0.540200024103731 TAS(ph)EINFDK ddPTM_PC-9_AZD4547_30min_R2 4 TASEINFDK 9 0 Q9Y4K4 Q9Y4K4 MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 1 T(0.093)AS(0.907)EINFDK;T(0.007)AS(0.993)EINFDK;T(0.103)AS(0.897)EINFDK;T(0.036)AS(0.964)EINFDK 133.05 0.0011819 60837300.0 152203.0 170120.0 184564.0 164085.0 171747.0 202270.0 182219.0 187481.0 182963.0 199177.0 True False 200600.38798093106 225107.96312208145 182116.56076802462 126257.73833797894 147902.89361901509 189622.02492455655 198436.13799502287 158510.1193347892 192634.05065363238 192203.8738547605 1.0436854573103735 1.1711936841199415 0.9475176390338605 0.656894867963931 0.7695104716296114 0.9865671337500985 1.032425278509068 0.8246978385803395 1.0022381276206584 1.0 17.55227788825259 -5.415929698443025 5.540951364313737 0.8867136630503487 1.1033244818060002 0.33395018896874407 0.11680235691585633 0.2515637261565756 10.805458197265287 0.032810010785819445 0.06957460712470118 3.837693632518483e-06 5.415929698443025 0.21661081875565147 TAS(ph)EINFDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASEINFDK 9 0 Q9Y4K4 Q9Y4K4 MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 1 T(0.08)AS(0.92)EINFDK 123.26 0.001507 15188000.0 52581.0 87364.0 61066.0 64016.0 83022.0 50972.0 93629.0 60644.0 54935.0 58581.0 True False 61481.92477791163 96036.92055143809 62522.045034094655 60429.391062672235 66754.43507841365 48298.938588922305 84759.7833047416 59052.15925762929 55738.32044819061 69201.27157305928 0.8884507954886646 1.3877912698475066 0.9034811588409467 0.8732410501861064 0.9646417408376322 0.6979487152621274 1.2248298532384108 0.8533392221743346 0.8054522580462246 1.0 16.078510927170008 -5.386396517426534 20.89269980616894 0.9136508990850275 1.1401308567375177 0.2118706326628681 0.17180859754212208 6.0557777743725785 984.7674945462903 0.042438397321695 0.08834261277989955 4.107745065088044e-06 5.386396517426534 0.22647995765249018 TAS(ph)EINFDK ddPTM_PC-9_Lapatinib_30min_R1 4 TASEINFDK 9 0 Q9Y4K4 Q9Y4K4 MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 1 T(0.271)AS(0.729)EINFDK;T(0.206)AS(0.794)EINFDK;T(0.228)AS(0.772)EINFDK;T(0.017)AS(0.983)EINFDK 130.44 0.0012659000000000001 67898300.0 140831.6 225786.0 205012.0 191925.0 260950.0 297670.0 308877.0 290636.0 257403.0 215293.0 True False 138823.31555864747 225263.2063892506 188156.70472920508 206039.80474303104 245601.4340474395 284939.3480026616 324869.13971323153 304140.009578881 228411.56356624505 252506.10819010923 0.5497820094479807 0.8921099295532775 0.745157042250811 0.8159794874661243 0.9726554173593644 1.128445367302298 1.2865793308597546 1.2044857518848502 0.9045783692261272 1.0 17.945958761901217 -6.380774484284788 1.952389131029379 1.1291206218899408 0.7464025817378448 0.6367237986457379 0.12620061782674044 0.21402457776316677 1.6108506466674064 0.045285549563485246 0.05424904462676649 4.161266361152936e-07 6.380774484284788 -0.382718040152096 TAS(ph)ELLLDR ddPTM_PC-9_AZD4547_30min_R2 2 TASELLLDR 9 0 Q92508 Q92508 PIEZO1 Piezo-type mechanosensitive ion channel component 1 1 T(0.178)AS(0.822)ELLLDR;TAS(1)ELLLDR 165.63 8.388e-05 12530300.0 24591.0 47242.0 43593.0 39743.0 36216.0 30109.0 43406.0 43899.0 30320.0 25395.1 True False 32410.426475424836 62512.052632338295 43014.928336839796 30580.865373229095 31188.03353366428 28226.27947027964 47269.049911436035 37115.41824866479 31922.653300493195 24506.025278666846 1.3225492958108953 2.550885013848277 1.7552796852080883 1.2478916929809323 1.272667973651945 1.1518097753229437 1.9288746083431578 1.5145425594975928 1.3026450816682509 1.0 14.580848886774787 -1.5228787452984085 0.1172717704956507 0.9232889740042662 3.974427074257916 0.21153356729202266 0.3881052080870159 159.14116752536506 1.2933274692387389 3.0585265409291793 79.06729831172522 0.029999999998751702 1.5228787452984085 3.0511381002536497 TAS(ph)ELLLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TASELLLDR 9 0 Q92508 Q92508 PIEZO1 Piezo-type mechanosensitive ion channel component 1 1 T(0.028)AS(0.972)ELLLDR;T(0.011)AS(0.989)ELLLDR;T(0.013)AS(0.987)ELLLDR;T(0.098)AS(0.902)ELLLDR 158.08 0.0001107 12465900.0 49249.8 62867.4 51196.4 33785.2 85449.0 36165.0 44744.1 33498.4 33292.6 28820.9 True False 57586.81841211065 69108.45999582774 52417.11633942823 31892.324777096255 68705.88185077911 34268.44373515608 40505.61492876877 32619.102494488663 33779.44129158878 34045.90102388112 1.6914464496538666 2.0298613905783367 1.5396013841037963 0.9367449184183946 2.0180368204262282 1.0065365493226002 1.189735436884357 0.9580919145481965 0.9921735150406086 1.0 15.055193494130727 -5.796084699489391 0.38877761649154985 0.9173627221677388 2.14362575902203 0.4739892794655145 0.3057909450214604 2.3938195073459605 0.5059813260464714 0.2925788637848052 1.2786797164834849 1.5992461007790027e-06 5.796084699489391 1.226263036854291 TAS(ph)ELLLDR ddPTM_PC-9_Lapatinib_30min_R1 2 TASELLLDR 9 0 Q92508 Q92508 PIEZO1 Piezo-type mechanosensitive ion channel component 1 1 T(0.027)AS(0.973)ELLLDR;T(0.077)AS(0.923)ELLLDR 147.28 0.00039065 13553000.0 36749.0 41561.0 16424.2 12396.4 16524.8 12437.7 11649.3 8398.2 22202.0 4481.5 True False 36224.95252105877 41464.768058000256 15073.865675245426 13308.072609178142 15552.843753006811 11905.7685646948 12252.443753537334 8788.411031136424 19701.376962575305 5256.1213037766065 6.891955194228597 7.88885295097873 2.867868681876618 2.531918850429894 2.9589963499951657 2.2651243905159335 2.3310808570444825 1.6720335249534313 3.7482728848779714 1.0 12.359782856048644 -5.292846476125445 6.028307919953395 2.443502641912847 7.403645631781564 0.8810572509684746 0.7305452501918871 0.047140668318973046 5.623056193089322 0.1790628933886243 0.39568791067879605 5.095109522568917e-06 5.292846476125445 4.960142989868717 TAS(ph)EPNLK ddPTM_PC-9_AZD4547_30min_R2 1 TASEPNLK 8 0 P56524-2;P56524;Q9UQL6-2;Q9UQL6;Q9UQL6-3;Q9UKV0-10;Q9UKV0-3;Q9UKV0-4;Q9UKV0-2;Q9UKV0;Q9UKV0-5;Q9UKV0-7 P56524-2;Q9UKV0-10 HDAC4;HDAC5;HDAC9 Histone deacetylase 4;Histone deacetylase 5;Histone deacetylase 9 1 T(0.342)AS(0.658)EPNLK 82.831 0.015913999999999998 59603000.0 182270.0 195290.0 296650.0 394630.0 296680.0 331990.0 244310.0 302070.0 282860.0 314750.0 True False 240228.0685484809 258413.67339590495 292716.22717233317 303654.15047272184 255491.10306956896 311230.6128180324 266053.11670881725 255392.022378053 297811.4021298648 303730.69830244425 0.790924558798697 0.8507986675044147 0.9637360622694013 0.9997479746691716 0.8411764253580979 1.0246926456808787 0.8759506964419217 0.840850213052033 0.9805113667941288 1.0 18.21243320464287 -5.046404314264811 3.659616073001516 0.9340444772286378 0.7981718888492552 0.3721780451645643 0.0639120853897562 0.241310336047299 6.473682564580048 0.01629097148654429 0.060848825557976785 8.986605677433958e-06 5.046404314264811 -0.13587258837938265 TAS(ph)EPNLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TASEPNLK 8 0 P56524-2;P56524;Q9UQL6-2;Q9UQL6;Q9UQL6-3;Q9UKV0-10;Q9UKV0-3;Q9UKV0-4;Q9UKV0-2;Q9UKV0;Q9UKV0-5;Q9UKV0-7 P56524-2;Q9UKV0-10 HDAC4;HDAC5;HDAC9 Histone deacetylase 4;Histone deacetylase 5;Histone deacetylase 9 1 T(0.028)AS(0.972)EPNLK;T(0.044)AS(0.956)EPNLK 85.355 0.013288 64308000.0 259390.0 231130.0 333360.0 329770.0 407670.0 379960.0 341970.0 319840.0 338500.0 274000.0 True False 303299.6038139728 254075.05891504438 341308.5666748394 311294.05602876545 327789.9899835816 360034.22871864826 309576.1259516023 311444.538898492 343449.92212091543 323674.03101719316 0.9370526355197828 0.7849720229842851 1.0544823926782978 0.961751719934028 1.0127163707062115 1.1123358509398726 0.956444126761464 0.9622166409820764 1.0610981704079676 1.0 18.30418209446141 -5.269510300839356 24.9997129424494 1.0131643066015297 0.8610123263436216 0.5273536701303569 0.05833840782175734 402.73817742598516 1247485.4452893366 0.014867050860029969 0.03183329780415537 5.376376809798884e-06 5.269510300839356 -0.1521519802579081 TAS(ph)EPNLK ddPTM_PC-9_Lapatinib_30min_R1 4 TASEPNLK 8 0 P56524-2;P56524;Q9UQL6-2;Q9UQL6;Q9UQL6-3;Q9UKV0-10;Q9UKV0-3;Q9UKV0-4;Q9UKV0-2;Q9UKV0;Q9UKV0-5;Q9UKV0-7 P56524-2;Q9UKV0-10 HDAC4;HDAC5;HDAC9 Histone deacetylase 4;Histone deacetylase 5;Histone deacetylase 9 1 T(0.003)AS(0.997)EPNLK;T(0.396)AS(0.604)EPNLK;T(0.229)AS(0.771)EPNLK;T(0.002)AS(0.998)EPNLK 99.53 0.0051711000000000005 149673100.0 999977.0 898440.0 869581.0 806776.0 1017409.0 940842.0 801588.0 773927.0 884491.0 729844.0 True False 985717.1446066791 896359.7173799891 798087.406859732 866108.9983658408 957567.0029230543 900604.3808698216 843090.304439794 809886.4737794194 784870.3094768581 855996.5629439994 1.151543344072009 1.0471534071318815 0.9323488450875288 1.0118136402172715 1.1186575324902324 1.052112146072648 0.9849225346655396 0.9461328571156932 0.916908248763851 1.0 19.70724547826697 -7.436129908134278 3.2373734686100724 0.9499555195835097 1.0476103902331872 0.3694617565509918 0.05841765943093593 0.30945654870574985 6.213986724282933 0.02993982628868561 0.018350245596384814 3.6632798057123475e-08 7.436129908134278 0.0976548706496776 TAS(ph)ESISNLSEAGSIK ddPTM_PC-9_AZD4547_30min_R2 1 TASESISNLSEAGSIK 16 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 T(0.226)AS(0.526)ES(0.032)IS(0.079)NLS(0.138)EAGSIK 218.83 2.9188999999999998e-22 57304000.0 26087.0 29465.0 38535.0 56704.0 34883.0 34796.0 35988.0 45964.0 42462.0 45254.0 True False 34382.123356691765 38988.98503052042 38024.00072167827 43631.76886806688 30040.097574409425 32620.200619344698 39190.86228200615 38861.31994764409 44706.45463210889 43669.671234245594 0.7873226975368075 0.8928160878835608 0.870718731032259 0.9991320666012024 0.6878938339900322 0.7469760979964525 0.897438912965134 0.8898926611833338 1.0237414976701327 1.0 15.414344049423997 -8.0639318171647 2.056682987583538 1.0144600231365901 0.8389250677200584 0.4043072946204843 0.08207878850870695 0.3702141264311777 2.8151659049466597 0.07531923976590534 0.024195698247621168 8.631140432562152e-09 8.0639318171647 -0.17553495541653175 TAS(ph)ESISNLSEAGSIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TASESISNLSEAGSIK 16 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 TAS(0.997)ES(0.003)ISNLSEAGSIK;T(0.004)AS(0.602)ES(0.185)IS(0.185)NLS(0.024)EAGS(0.001)IK 218.63 3.0592000000000003e-22 47245000.0 27427.9 33796.0 28206.7 35555.0 43477.0 34727.9 39477.0 36967.0 43919.0 30524.2 True False 32070.90174428181 37151.04353001705 28879.25470250546 33562.96862086529 34957.99395225594 32906.70778902604 35737.452771270524 35996.65541977416 44561.2322884151 36057.995830565735 0.889425521456627 1.0303136010272862 0.8009112552513253 0.9308051611791066 0.9694935380358178 0.9126050139794957 0.9911103473193179 0.9982988402605677 1.2358211060261237 1.0 15.13803159091601 -7.885829524166 2.3457344902227426 1.1156698244963137 0.9279076881655737 0.45162806746206696 0.079761210958004 0.25621486246836517 2.7282826988790343 0.05527781845295737 0.02115718306891312 1.3006800404275858e-08 7.885829524166 -0.18776213633074001 TAS(ph)ESISNLSEAGSIK ddPTM_PC-9_Lapatinib_30min_R1 1 TASESISNLSEAGSIK 16 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 T(0.001)AS(0.998)ES(0.001)ISNLSEAGSIK 242.67 6.093399999999999e-40 48148000.0 85218.0 81595.0 70251.0 70399.0 86409.0 78498.0 84281.0 79223.0 84383.0 67730.0 True False 84002.77569293266 81406.07179068177 64475.233956702024 75576.37730417971 81326.59250663029 75140.82352777553 88644.65778989982 82903.98979778045 74878.89794761696 79437.04025544782 1.0574761524699645 1.0247873224997066 0.8116520171115047 0.951399713045032 1.023786790710054 0.9459167069435513 1.115910883699126 1.043643991910875 0.9426194342944662 1.0 16.277524250044955 -6.763161542495671 1.8751584631571663 1.0248145977550829 0.9604047577558926 0.07643732579975371 0.07639526676046099 0.8113678767075843 5.887810212024105 0.03312028761989467 0.03029211021623947 1.7251960594848778e-07 6.763161542495671 -0.06440983999919025 TAS(ph)ESNVYLNSFHYPDHSYK ddPTM_PC-9_AZD4547_30min_R2 2 TASESNVYLNSFHYPDHSYK 20 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;E9PGF6;A0A1W2PRJ2;A0A1W2PRT1 E9PFQ4;A0A1W2PRT1 PHLDB2 Pleckstrin homology-like domain family B member 2 1 T(0.126)AS(0.621)ES(0.143)NVY(0.095)LNS(0.015)FHYPDHSYK;T(0.151)AS(0.797)ES(0.051)NVYLNSFHYPDHSYK 103.53 0.00010112 8900400.0 24140.0 30175.7 68571.0 84517.0 84012.0 100384.0 60779.0 99233.0 81366.0 74064.0 True False 31816.017856807593 39929.40490702445 67661.70373650455 65032.9114246333 72348.38395267852 94106.97261099835 66188.21325547552 83898.81999748856 85666.84064801867 71471.04190332723 0.44515956406291657 0.5586794853366422 0.9467009565639851 0.909919733821675 1.0122754898485737 1.3167147155667438 0.9260843481896158 1.1738855033199505 1.1986230837923544 1.0 16.12507119955366 -5.100307555851352 0.8685266896397232 1.1196816050901093 0.204803722643069 0.8044165168894207 0.1138706846831743 0.6258528211052454 0.5078089095570081 0.04219786324642194 0.4976790347330891 7.937659116380438e-06 5.100307555851352 -0.9148778824470403 down TAS(ph)ESNVYLNSFHYPDHSYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TASESNVYLNSFHYPDHSYK 20 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;E9PGF6;A0A1W2PRJ2;A0A1W2PRT1 E9PFQ4;A0A1W2PRT1 PHLDB2 Pleckstrin homology-like domain family B member 2 1 T(0.184)AS(0.76)ES(0.056)NVYLNSFHYPDHSYK;T(0.222)AS(0.706)ES(0.071)NVYLNSFHYPDHSYK 115.58 1.0885e-05 17956300.0 26675.0 54227.0 74302.0 76518.0 88883.0 73914.0 85028.0 56017.0 74142.0 56342.0 True False 31190.550644734656 59610.29818624196 76073.64147190405 72230.94453470297 71467.0142019543 70037.81972183946 76973.53229058906 54546.61310491755 75226.18648711649 66556.35859697344 0.4686336708053166 0.8956364116493696 1.1429958470619124 1.0852598618276508 1.0737819151843466 1.0523084675642747 1.1565165810331657 0.8195552499381777 1.1302629541775637 1.0 16.022288883073564 -4.804068933803765 2.898285923578845 1.0554435841493273 0.3828597720520251 0.7882317859159378 0.09204816904174316 0.161112689049052 1.9839433927179795 0.023050514029961035 0.2519735968521003 1.570113566787991e-05 4.804068933803765 -0.6725838120973022 down TAS(ph)ESNVYLNSFHYPDHSYK ddPTM_PC-9_Lapatinib_30min_R1 1 TASESNVYLNSFHYPDHSYK 20 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;E9PGF6;A0A1W2PRJ2;A0A1W2PRT1 E9PFQ4;A0A1W2PRT1 PHLDB2 Pleckstrin homology-like domain family B member 2 1 T(0.132)AS(0.677)ES(0.15)NVY(0.041)LNSFHYPDHSYK 77.641 0.0010967000000000001 7163000.0 15451.0 13553.0 30855.0 14825.0 26110.0 24737.0 18702.0 25867.0 34012.0 19413.0 True False 15230.665906633614 13521.618861193845 28318.22100374435 15915.27995475025 24574.26113423507 23679.056174763442 19670.298050411202 27068.875252126145 30181.21039776196 22768.51118380349 0.6689355216808394 0.5938736508521701 1.2437449587783622 0.6990039808167904 1.0793090920989208 1.0399914154952596 0.8639255281831418 1.1888733098799074 1.325568024809261 1.0 14.47475233734076 -4.226869730612911 0.42874946911039946 1.1195290262761082 5.285812635472511e-15 0.3962290698658787 0.18774782018766015 8.811213481705671 0.8828912527652507 0.1363708005938439 5.5379440070754615 5.931032029720052e-05 4.226869730612911 -1.1195290262761028 TAS(ph)FGNILDVPEIVISGNGQPR ddPTM_PC-9_AZD4547_30min_R2 1 TASFGNILDVPEIVISGNGQPR 22 0 O43318-3;O43318 O43318-3 MAP3K7 Mitogen-activated protein kinase kinase kinase 7 1 T(0.194)AS(0.806)FGNILDVPEIVISGNGQPR 154.08 3.4049000000000002e-06 6904200.0 22458.0 23466.0 28679.0 38999.0 30500.0 31625.0 32013.0 35219.0 26647.0 27802.0 True False 29599.176844580998 31050.925597359343 28298.697721474295 30008.38307854368 26265.601468322322 29647.48375062584 34862.09498260152 29776.71280210766 28055.506019071294 26828.660442270208 1.1032670419111075 1.157378903213397 1.0547935400042543 1.118519619834005 0.979012780934051 1.1050676128396781 1.2994347987525363 1.1098844411625046 1.0457289166352903 1.0 14.711487402036823 -7.004611219465388 24.989557481868516 1.1342522333653697 1.0826844095628825 0.007471797231002997 0.08517739758397086 591.5951534061729 3206038.717002457 0.030919818656845035 0.026623783422922962 9.894384438710039e-08 7.004611219465388 -0.051567823802487256 TAS(ph)FGNILDVPEIVISGNGQPR ddPTM_PC-9_Lapatinib_30min_R1 2 TASFGNILDVPEIVISGNGQPR 22 0 O43318-3;O43318 O43318-3 MAP3K7 Mitogen-activated protein kinase kinase kinase 7 1 T(0.052)AS(0.948)FGNILDVPEIVISGNGQPR;T(0.026)AS(0.974)FGNILDVPEIVISGNGQPR 156.32 6.2559000000000005e-06 27663000.0 110129.0 98976.0 108698.0 98033.0 120373.0 126040.0 115622.0 102752.0 140431.0 116209.0 True False 108558.54026481503 98746.82715306748 99761.27002641404 105242.67384850133 113292.89680242358 120649.56301359046 121608.34141720901 107526.233034618 124614.18197601169 136295.57081124067 0.7964935296038388 0.7245050339150387 0.7319479967883626 0.7721650323784526 0.8312294825730316 0.8852053100146682 0.8922398629198861 0.7889194960233441 0.9142937018004287 1.0 17.056379154169925 -6.38881649797997 2.0329327824831798 0.8832524099804788 0.7483526953629531 0.6132521630131462 0.05191576620732927 0.23495078289625873 1.9152552358105823 0.01790193505322652 0.021232786122277404 4.084919495750747e-07 6.38881649797997 -0.1348997146175257 TAS(ph)FSESR ddPTM_PC-9_AZD4547_30min_R2 4 TASFSESR 8 0 P53396;P53396-2;P53396-3 P53396 ACLY ATP-citrate synthase 1 T(0.001)AS(0.999)FSESR;T(0.042)AS(0.935)FS(0.023)ESR;T(0.32)AS(0.645)FS(0.032)ES(0.004)R;T(0.004)AS(0.482)FS(0.482)ES(0.032)R 133.99 0.0035428000000000005 920165900.0 192270.0 171908.0 257483.0 260930.0 258762.0 265841.0 234841.0 319899.0 248049.0 232081.0 True False 253407.8605355594 227473.89915583585 254068.60718359618 200776.61982831376 222837.3628572461 249217.9202450627 255741.39405270125 270465.9600977155 261160.3637379297 223955.91482995832 1.1315077823595903 1.01570837871618 1.1344581248345298 0.8965006348716275 0.9950054814423567 1.112799009726021 1.14192739337506 1.2076750029266723 1.166123984428897 1.0 17.772855243703262 -6.916960573542162 4.945089696995987 1.1439790154163787 1.0318805358690013 0.23231885658184903 0.08110030470100421 0.2707998745186766 11.654452066894885 0.029301529962596624 0.02566049802555523 1.210708039996082e-07 6.916960573542162 -0.1120984795473774 TAS(ph)FSESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 TASFSESR 8 0 P53396;P53396-2;P53396-3 P53396 ACLY ATP-citrate synthase 1 T(0.005)AS(0.995)FS(0.001)ESR;T(0.001)AS(0.992)FS(0.003)ES(0.004)R;T(0.076)AS(0.923)FS(0.001)ESR;T(0.009)AS(0.981)FS(0.009)ES(0.001)R;T(0.001)AS(0.997)FS(0.002)ESR;T(0.076)AS(0.921)FS(0.002)ES(0.001)R 122.94 0.0033068000000000004 746251900.0 273997.0 341404.0 354297.0 347556.0 416942.0 365045.0 467016.0 371439.0 390064.0 323075.0 True False 320379.28041257267 375296.33285956667 362744.78415885573 328083.56411175476 335245.20814319124 345901.3975750051 422776.86357696 361689.1198221524 395767.9480714112 381645.94003970776 0.8394672831557943 0.98336257113208 0.9504746313326811 0.8596542755770435 0.8784194274628238 0.9063410907476608 1.1077724645334177 0.9477085483590394 1.0370029038701005 1.0 18.54187531841724 -7.219211515559674 22.199998199081243 1.0187633159191303 0.905684801600803 0.5440492865812095 0.053799182059068584 107.7753871668959 56659.33044243344 0.020419845824788237 0.015816775142552603 6.036545583373643e-08 7.219211515559674 -0.11307851431832727 TAS(ph)FSESR ddPTM_PC-9_Lapatinib_30min_R1 4 TASFSESR 8 0 P53396;P53396-2;P53396-3 P53396 ACLY ATP-citrate synthase 1 T(0.01)AS(0.929)FS(0.051)ES(0.011)R;T(0.001)AS(0.961)FS(0.035)ES(0.003)R;T(0.087)AS(0.909)FS(0.003)ES(0.001)R;T(0.002)AS(0.926)FS(0.072)ES(0.001)R 123.21 0.003295 649692000.0 202031.0 203060.0 231244.0 230717.0 282507.0 284334.0 313217.0 333453.0 318175.0 279309.0 True False 199150.0008920523 202589.82704596946 212232.01094765333 247684.69782935004 265890.49369013193 272173.6976349269 329433.84367744863 348946.44371002517 282338.78096871416 327587.1884941522 0.6079297600357999 0.6184302505150805 0.6478641973858569 0.7560878646320184 0.8116632854672166 0.8308435347732943 1.0056371410365132 1.0652017416006312 0.8618736961801368 1.0 18.32151941060568 -6.415412362716696 0.8091131251695397 0.9948654763689407 0.5973968647946908 0.8697327998465527 0.05686633943376267 0.21688586803307014 0.31265821029380325 0.03342531298132426 0.04716655650715049 3.842267853639598e-07 6.415412362716696 -0.39746861157424995 TAS(ph)FSESRADEVAPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASFSESRADEVAPAK 16 1 P53396;P53396-2;P53396-3 P53396 ACLY ATP-citrate synthase 1 T(0.294)AS(0.543)FS(0.158)ES(0.005)RADEVAPAK 69.361 0.010205 18648000.0 42534.0 18392.0 44351.0 60449.0 69357.0 74583.0 69811.0 79019.0 89673.0 54131.0 True False 49734.166115206885 20217.83621150649 45408.496042104154 57062.238508302195 55766.99373339043 70671.73618413229 63197.99669212873 76944.83497755099 90984.29798035101 63944.52179923976 0.7777705535331437 0.31617776851913 0.7101233188461192 0.8923710257378235 0.8721152674888476 1.1052039204548796 0.9883254251325106 1.2033061286958562 1.42286306035731 1.0 15.964533146606234 -6.233297331449665 0.756587208261914 1.198919023865036 0.5130629978119197 0.6747007908262963 0.16229026405488237 0.41427959228228517 0.5073263116689833 0.09198620534338639 0.16764706356486173 5.84389855765627e-07 6.233297331449665 -0.6858560260531164 TAS(ph)FSESRADEVAPAK ddPTM_PC-9_Lapatinib_30min_R1 1 TASFSESRADEVAPAK 16 1 P53396;P53396-2;P53396-3 P53396 ACLY ATP-citrate synthase 1 T(0.034)AS(0.891)FS(0.057)ES(0.019)RADEVAPAK 130.27 6.9442e-05 13838000.0 22625.0 12404.0 17546.0 15978.0 17666.0 17918.0 15745.0 14628.0 20083.0 15465.0 True False 22302.363351083153 12375.279300099482 16103.43560951865 17153.075421045487 16626.920612692335 17151.68890889808 16560.199059123315 15307.670282139461 17821.041056634534 18138.104644182808 1.2295862102789166 0.6822807312487549 0.8878235033605505 0.9456928249968369 0.9166845675920645 0.9456163830435784 0.9130060380611184 0.8439509299583232 0.9825194752280823 1.0 14.14673608771462 -8.472018978894022 11.808524625662134 0.9999993075519833 0.9128415754236484 0.045447492654943966 0.12689582807408717 2.997677583879817 691.4281515858876 0.11381433010207391 0.029389952635988485 3.3727256935067162e-09 8.472018978894022 -0.08715773212833489 TAS(ph)GSSVTSLDGTR ddPTM_PC-9_AZD4547_30min_R2 3 TASGSSVTSLDGTR 14 0 Q92597;E5RJY1;E7ESM1;Q92597-3;Q92597-2 Q92597 NDRG1 Protein NDRG1 1 T(0.002)AS(0.997)GS(0.001)SVTSLDGTR;TAS(0.927)GS(0.052)S(0.003)VT(0.018)SLDGTR;T(0.125)AS(0.801)GS(0.071)S(0.003)VTSLDGTR 211.82 1.4112999999999999e-11 173489000.0 150898.0 115062.0 190397.0 222860.0 204315.0 171749.0 139194.0 170322.0 137009.0 143014.0 True False 198880.42512661725 152253.54133995404 187872.21137681013 171483.07015267698 175949.38898361573 161009.50787940677 151581.99634549193 144002.6485101958 144251.01603058298 138007.12339007374 1.4410881137235694 1.1032295840962727 1.3613225662692348 1.242566803366985 1.2749297620406095 1.1666753419989586 1.0983635671982608 1.0434435916990739 1.0452432634427211 1.0 17.074383209659842 -7.173646017466519 1.1487796544576023 1.0211710444217632 1.2846351071035196 0.6608368031979412 0.08150376386055902 0.29891406611082466 0.7815015717757253 0.049484415438283004 0.030398350079752976 6.70430838129174e-08 7.173646017466519 0.2634640626817564 TAS(ph)GSSVTSLDGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TASGSSVTSLDGTR 14 0 Q92597;E5RJY1;E7ESM1;Q92597-3;Q92597-2 Q92597 NDRG1 Protein NDRG1 1 T(0.063)AS(0.858)GS(0.065)S(0.004)VT(0.004)S(0.004)LDGT(0.001)R;T(0.013)AS(0.977)GS(0.01)SVTSLDGTR;T(0.137)AS(0.85)GS(0.013)SVTSLDGTR;T(0.001)AS(0.841)GS(0.15)S(0.008)VTSLDGTR 203.85 1.1669e-10 176485000.0 81562.0 80165.8 56269.6 105806.0 153657.0 166146.0 199066.0 170221.0 167043.0 142998.0 True False 95368.83567707003 88124.13082668498 57611.28066764636 99878.03284768021 123549.01388600386 157433.01127668296 180209.02736696627 165752.87911405764 169485.68786069137 168922.40542845466 0.5645718543681437 0.5216840868632376 0.3410517421979704 0.5912657506524942 0.7313950661111783 0.9319841904771009 1.0668154227965452 0.9812367914939535 1.0033345631730024 1.0 17.36600117058515 -6.528711113944246 1.6851568712787597 1.0129125343056953 0.48178968704800285 0.9333520266943861 0.06257383824383109 0.0871276971427762 0.5023528261403214 0.025480158938740335 0.027764682076019915 2.959980745824367e-07 6.528711113944246 -0.5311228472576924 TAS(ph)GSSVTSLDGTR ddPTM_PC-9_Lapatinib_30min_R1 2 TASGSSVTSLDGTR 14 0 Q92597;E5RJY1;E7ESM1;Q92597-3;Q92597-2 Q92597 NDRG1 Protein NDRG1 1 T(0.27)AS(0.729)GS(0.001)SVTSLDGTR;T(0.137)AS(0.859)GS(0.004)SVTSLDGTR 206.45 8.320600000000001e-11 103554000.0 34443.9 46194.0 60487.0 50796.0 79293.0 92725.0 103678.0 102886.0 98445.0 99981.0 True False 33952.72366976232 46087.0406311509 55513.992346572166 54531.7072904886 74629.14163603612 88759.36790253225 109045.93953964987 107666.45916380937 87357.08742819219 117262.58263369159 0.28954439606557936 0.39302426738390195 0.4734160812404112 0.46503928248652343 0.6364275795388619 0.7569283049120745 0.9299295401013884 0.9181655115011506 0.7449698400476211 1.0 16.83938321107309 -6.458009699398452 0.9022587616276534 0.9100771264212122 0.34516468771098 0.9109287731903568 0.07022179068579926 0.16169924320748377 0.2872357469126666 0.03825656856638723 0.04939409232652392 3.483295354651763e-07 6.458009699398452 -0.5649124387102322 down TAS(ph)ISSSPSEGTPTVGSYGCTPQSLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASISSSPSEGTPTVGSYGCTPQSLPK 27 0 Q6PKG0;Q6PKG0-3 Q6PKG0 LARP1 La-related protein 1 1 T(0.189)AS(0.59)IS(0.162)S(0.045)S(0.013)PSEGTPTVGSYGCTPQSLPK 99.774 1.041e-09 5602500.0 77656.0 77363.0 57913.0 69544.0 81341.0 64015.0 66793.0 62994.0 56418.0 49968.0 True False 90801.62702408675 85043.08736574482 59293.86555627555 65647.67514468999 65402.81496125428 60657.94070803308 60465.88350055661 61340.474247660124 57243.0065176302 59026.80285352962 1.5383117945487215 1.4407537466796665 1.004524431103081 1.1121672184683549 1.1080189303755148 1.0276338506517286 1.0243801218676531 1.0391969627742113 0.9697798923596495 1.0 15.84908258085937 -5.198949343497433 4.292588876826393 1.0410354891781952 1.5129608912344292 0.9413867021618109 0.045432499427044214 0.04718635270035063 1.751431996581959 0.012368412286487246 0.035422304971153375 6.324856207707687e-06 5.198949343497433 0.471925402056234 TAS(ph)LNQRPR ddPTM_PC-9_AZD4547_30min_R2 1 TASLNQRPR 9 1 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 T(0.042)AS(0.958)LNQRPR 103.31 0.0013666 59474000.0 12495.0 11610.0 15941.0 23673.0 22610.0 14673.0 12252.0 23614.0 15091.0 19058.0 True False 16468.150087854632 15362.70545407577 15729.611924335635 18215.555594204066 19470.991777008774 13755.494990448471 13342.404264731003 19964.998895737263 15888.679451112897 18390.78522080373 0.8954566044970063 0.8353479892037137 0.8552985495443792 0.990471879014636 1.058736293379312 0.7479558281659556 0.72549399628886 1.0855979587621292 0.8639478554259641 1.0 14.166695458536669 -7.778627575580446 24.999897429560054 0.981079580207374 0.8774651079366309 0.1838138205407137 0.10634309472554704 502.73596488085303 731209.2578561702 0.06125226613020074 0.029538966341864908 1.6648397032416826e-08 7.778627575580446 -0.10361447227074305 TAS(ph)LNQRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASLNQRPR 9 1 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 T(0.041)AS(0.959)LNQRPR 77.744 0.010669 56869000.0 24554.0 21363.0 20275.0 16633.0 23091.0 17896.0 14821.0 22809.0 14480.0 10472.0 True False 28710.507236394176 23483.777456851512 20758.432893365694 15701.106934913578 18566.484310130447 16957.502255892516 13417.047585252185 22210.287918133152 14691.742606531347 12370.490703693615 2.320886691085077 1.8983707291287695 1.6780605871331835 1.269238812832663 1.5008688624281343 1.370802716082176 1.0846010806383037 1.7954249714202157 1.1876442865879724 1.0 13.594615108784039 -4.821752575462309 0.9420551835915376 1.3320829255984463 2.8192725311569187 0.6996153045492228 0.2151131367931658 1.1025019159246074 0.8049245644352944 0.0712283796392934 1.6638743328268322 1.5074656489675718e-05 4.821752575462309 1.4871896055584723 TAS(ph)LPGYGR ddPTM_PC-9_AZD4547_30min_R2 1 TASLPGYGR 9 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;O14639-4 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 T(0.128)AS(0.872)LPGYGR 115.23 0.0019913 61606000.0 42412.0 27941.0 44423.0 81546.0 49699.0 63680.0 48800.0 81505.0 58312.0 48136.0 True False 55898.1337755975 36972.381833964784 43833.921994527445 62746.82957314097 42799.15171718525 59698.079533276 53143.105461873376 68910.2750485757 61394.25327369261 46450.7732914581 1.2033843532563253 0.7959476067702772 0.9436639885301571 1.3508242194254185 0.9213872812975461 1.2851902197342744 1.144073643907365 1.4835119022926515 1.3217057311074407 1.0 15.503414993691619 -6.481748112998055 0.8859592065252228 1.2829173303797983 0.9900184613640085 0.17646625549309813 0.19135794089600425 0.8430543288670506 1.449537786339655 0.10414262519844128 0.13164070712488324 3.298009383777481e-07 6.481748112998055 -0.29289886901578976 TAS(ph)LPGYGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TASLPGYGR 9 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;O14639-4 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 T(0.278)AS(0.722)LPGYGR;T(0.094)AS(0.904)LPGY(0.001)GR;T(0.012)AS(0.987)LPGY(0.001)GR 102.06 0.0032981 61924700.0 168636.0 166407.0 197828.0 243380.0 274919.0 198502.0 206016.0 199115.0 198591.0 174954.0 True False 197182.7440871779 182926.78721444955 202544.9697868679 229744.20764860633 221050.5954725543 188092.20567720037 186500.67305332384 193888.44222978115 201495.01767773938 206671.77526489797 0.9540864679487189 0.8851077365546713 0.9800320799841169 1.1116380422732406 1.069573216706667 0.9101010790472789 0.9024003050938129 0.9381466916866998 0.9749517921326056 1.0 17.656981850787318 -9.992412907617247 15.173782270631396 1.0000141132428415 0.9698562172244095 0.017515953545563567 0.06836120227400003 0.0 0.0 0.07468142556369313 0.018112906227694694 1.0176234175004196e-10 9.992412907617247 -0.030157896018431996 TAS(ph)LPGYGR ddPTM_PC-9_Lapatinib_30min_R1 1 TASLPGYGR 9 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;O14639-4 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 T(0.027)AS(0.973)LPGYGR 90.149 0.008796600000000002 72288000.0 40307.0 37901.0 45133.0 35599.0 42899.0 39970.0 30914.0 39339.0 45047.0 23066.0 True False 39732.21478860149 37813.24256313049 41422.338958418164 38217.06921478272 40375.765162679076 38260.57627462081 32514.57565663628 41166.83355408011 39973.332494060436 27052.927366486925 1.4686844883863337 1.3977504929826339 1.531159212356886 1.4126777740927918 1.4924730553447032 1.4142859941293409 1.2018875153938138 1.521714563322173 1.477597302226866 1.0 14.72349709443726 -11.13662816396217 2.9400058497257056 0.9683050046528533 1.4331364653395438 0.6814558873676606 0.0892849037429684 61661385.71579059 68300884.52279879 15156893.00136914 0.022498166303416396 7.30082327630607e-12 11.13662816396217 0.46483146068669046 TAS(ph)LTSAASVDGNR ddPTM_PC-9_Lapatinib_30min_R1 2 TASLTSAASVDGNR 14 0 Q9UN36-6;Q9UN36-2;Q9UN36-5;Q9UN36-4;A0A0A0MS87;H0YJT9;G3V578;Q9UN36-3;Q9UN36 Q9UN36-6;Q9UN36-3 NDRG2 Protein NDRG2 1 T(0.007)AS(0.991)LT(0.001)SAASVDGNR;TAS(0.995)LT(0.003)S(0.001)AASVDGNR 135.14 3.4968e-05 62775000.0 37518.0 44345.0 46068.0 43063.0 53261.0 72496.0 74967.0 74578.0 85104.0 46083.0 True False 36982.986440041444 44242.3218770487 42280.46686762255 46229.99667395684 50128.292695154865 69395.5150764301 78848.42444365192 78043.16614037454 75518.6913351503 54048.385148262256 0.6842570104285625 0.8185688019297125 0.782270677498344 0.855344642529865 0.9274706831230197 1.2839516830349054 1.4588488486262763 1.4439500075033 1.397242325149808 1.0 15.721963893468722 -6.699138405966618 2.3821574841510387 1.36721111690155 0.7890184053767346 0.7942000498637303 0.1290931183813863 0.11718006304964443 1.3611759470316696 0.0465116433075257 0.04468344643330755 1.9992246321691674e-07 6.699138405966618 -0.5781927115248153 TAS(ph)LVSR ddPTM_PC-9_Lapatinib_30min_R1 1 TASLVSR 7 0 Q9UL54-2;Q9UL54-3;Q9UL54-4;Q9UL54 Q9UL54-2 TAOK2 Serine/threonine-protein kinase TAO2 1 T(0.46)AS(0.54)LVSR 85.86200000000001 0.019 33283000.0 155200.0 119640.0 186380.0 123570.0 106340.0 146450.0 80777.0 112270.0 151820.0 109750.0 True False 152986.8195398057 119362.98093065948 171056.55584760572 132657.75001743596 100085.29027248388 140186.6748916242 84959.23781510354 117486.47406178554 134720.43286452486 128720.14126731733 1.1885227753292544 0.9273061679040149 1.328902797677692 1.0305904632433651 0.7775417994968905 1.0890811143571846 0.6600306446111328 0.9127279764073404 1.0466150171848128 1.0 16.97387828893544 -6.003083330625518 24.984846669768462 0.9058164282860588 1.1350828984332777 0.33012616677804774 0.1492604026049733 144.07961320324736 1167530.3204564913 0.04079453437405799 0.05922118046175837 9.9292551170921e-07 6.003083330625518 0.2292664701472189 TAS(ph)LVTR ddPTM_PC-9_Lapatinib_30min_R1 2 TASLVTR 7 0 Q7L7X3;Q7L7X3-3;Q7L7X3-2 Q7L7X3 TAOK1 Serine/threonine-protein kinase TAO1 1 T(0.003)AS(0.918)LVT(0.079)R;T(0.019)AS(0.801)LVT(0.181)R 106.68 0.010019 17029300.0 151842.0 130112.0 180988.0 157833.0 131724.0 124084.0 110364.0 96576.0 151753.0 107403.0 True False 149676.70523558746 129810.73365805755 166107.86527388368 169440.56533545363 123976.25329934814 118777.21657393174 116078.10790480068 101063.27352802156 134660.9791100662 125967.46544449845 1.1882171694685353 1.0305100066909931 1.3186568824556621 1.3451137143829375 0.984192647378242 0.9429197940500379 0.9214927639863085 0.8022966340665977 1.0690139603499296 1.0 16.94269164067947 -6.400045253334745 5.748152302927773 0.936405385030416 1.2129769684945804 0.6251861673845346 0.1013835879121148 0.1585999740108262 6.805801174935122 0.033174215003473985 0.0375872440476296 3.980656900852368e-07 6.400045253334745 0.27657158346416433 TAS(ph)NPKVENEDEPVR ddPTM_PC-9_AZD4547_30min_R2 2 TASNPKVENEDEPVR 15 1 Q9UBF8-2 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 T(0.448)AS(0.552)NPKVENEDEPVR;T(0.089)AS(0.911)NPKVENEDEPVR 77.027 0.0062954 80274000.0 111310.0 97771.0 142787.0 183885.0 170586.0 146457.0 133917.0 144539.0 138906.0 147219.0 True False 146704.2646081711 129373.56373388818 140893.55108463168 141493.15424492955 146903.07842869606 137299.02063764143 145835.35356839583 122203.8187257968 146248.28757778063 142064.90761997635 1.0326566008870046 0.9106651734146936 0.9917547791712359 0.9959754074061961 1.0340560585282736 0.9664527499283379 1.0265403047915636 0.8601970801451688 1.02944696215194 1.0 17.11619070350698 -10.163659539801719 12.128620306386846 0.9999999999956257 0.9802610849551399 0.006153097578242894 0.054798610550800333 0.0 0.0 0.05044095584617864 0.012233728753583011 6.860258178094463e-11 10.163659539801719 -0.01973891504048586 TAS(ph)NPKVENEDEPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TASNPKVENEDEPVR 15 1 Q9UBF8-2 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 T(0.153)AS(0.847)NPKVENEDEPVR;T(0.057)AS(0.943)NPKVENEDEPVR;T(0.483)AS(0.517)NPKVENEDEPVR 123.92 0.00014813 99081000.0 120505.0 103061.0 98801.0 157572.0 155218.0 143708.0 139974.0 154810.0 121052.0 107522.0 True False 140904.11641776015 113292.21497357919 101156.79054487882 148743.75169531663 124804.14714173584 136171.69949652458 126714.64939599796 150746.40153475318 122822.15649211573 127014.88745631614 1.1093511889794878 0.8919601256391575 0.7964168025552861 1.1710733652893535 0.9825946362756836 1.0720924312384854 0.9976361978793907 1.1868404133853911 0.9669902398989063 1.0 16.954638080100587 -5.766373643990205 24.9997781988082 1.057118547803377 0.9285144551359741 0.23182434604382318 0.10099667666747876 164.4056137513416 832977.5294624399 0.027394664298097844 0.04211234109146432 1.7124833434915922e-06 5.766373643990205 -0.12860409266740302 TAS(ph)NPKVENEDEPVR ddPTM_PC-9_Lapatinib_30min_R1 2 TASNPKVENEDEPVR 15 1 Q9UBF8-2 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 T(0.095)AS(0.905)NPKVENEDEPVR;T(0.45)AS(0.55)NPKVENEDEPVR 111.11 0.0022052 54545000.0 73816.0 79654.0 70403.0 59178.0 66341.0 69292.0 71857.0 61293.0 64758.0 50344.0 True False 72763.37030380337 79469.5660569272 64614.73710343913 63530.147532020936 62438.9528114243 66328.54268754128 75577.40386099879 64140.89654109743 57464.2721080286 59045.893320836665 1.2323188999517762 1.3458948893382774 1.0943138204776264 1.075945234443626 1.05746478374289 1.1233387955896104 1.2799773127376555 1.086288866739235 0.973213696603521 1.0 15.849549102310045 -1.5228787452803385 0.35052230747738955 1.0672180157708555 3.777950178601868 0.3644119860525096 0.09172361258907537 75.6819819117634 1.0649405708904047 0.08330138352788387 135.65383806035013 0.029999999999999933 1.5228787452803385 2.710732162831013 TAS(ph)PPALPK ddPTM_PC-9_AZD4547_30min_R2 1 TASPPALPK 9 0 Q13029-5;Q13029-3;Q13029-2;Q13029 Q13029-5 PRDM2 PR domain zinc finger protein 2 1 T(0.189)AS(0.811)PPALPK 89.82700000000001 0.0090455 11958000.0 58743.0 59181.0 72024.0 91647.0 76582.0 71738.0 62702.0 75834.0 67326.0 75186.0 True False 77422.05206969545 78310.10090246839 71068.91470035433 70519.20008203521 65949.91120154309 67252.21151944324 68282.35653013096 64115.59779195978 70884.7149112468 72553.76102483724 1.0670990859204619 1.0793389590880147 0.9795345368247058 0.9719578845525936 0.9089799104827458 0.9269293634057216 0.9411277315693661 0.8836977833583454 0.9769957326813276 1.0 16.14676278186687 -5.444261980566785 1.7185075874762206 0.9347768452495012 1.0816760197704107 0.70067179703727 0.03289938675395545 0.19638230221300487 1.0820303128543798 0.009267220209180579 0.030346044469749776 3.5953238808909545e-06 5.444261980566785 0.1468991745209095 TAS(ph)PPALPK ddPTM_PC-9_Lapatinib_30min_R1 2 TASPPALPK 9 0 Q13029-5;Q13029-3;Q13029-2;Q13029 Q13029-5 PRDM2 PR domain zinc finger protein 2 1 T(0.226)AS(0.774)PPALPK;T(0.062)AS(0.938)PPALPK 101.97 0.0033260999999999994 13646700.0 113916.0 119936.0 108199.0 91830.0 85688.0 111918.0 104116.0 106006.0 108318.0 72843.0 True False 112291.5369503642 119658.29556084613 99303.29588021827 98583.48453589993 80648.00030908972 107131.5280336006 109506.61703649948 110931.42575392904 96118.08620089317 85433.8154928037 1.3143687461766564 1.4005964133830036 1.16234181169847 1.1539164435914004 0.9439821907039011 1.2539710115443052 1.281771350194742 1.2984486893632075 1.125059037179364 1.0 16.382519594449484 -1.5229020025896414 0.020152694723462754 6.495862712508564e-07 2.737902865076969 0.24968150002953826 0.11841565262154385 5677.502856499272 8.850306110468527 445.0737862561554 806.7808017513422 0.029998393485005194 1.5229020025896414 2.7379022154906973 TAS(ph)PPGPPPYGK ddPTM_PC-9_AZD4547_30min_R2 2 TASPPGPPPYGK 12 0 P54259 P54259 ATN1 Atrophin-1 1 T(0.011)AS(0.989)PPGPPPYGK;T(0.177)AS(0.823)PPGPPPYGK 83.226 0.011254 64413000.0 362000.0 305460.0 385130.0 511470.0 472190.0 469710.0 356330.0 426160.0 346920.0 397110.0 True False 477108.46993224375 404193.97140413243 380022.9245605279 393558.49363272695 406634.5690926925 440338.9594468446 388042.679697323 360306.764182578 365257.4829487833 383207.29977087706 1.245040139416736 1.0547658451334394 0.9916902021118775 1.0270119955127133 1.0611347156899746 1.1490881298715527 1.0126181832374723 0.9402398242361472 0.9531589903615456 1.0 18.54776551787765 -4.768072735885347 3.662297664825582 1.0212066701834182 1.2731084806687545 0.6018084657273417 0.055311487989647114 0.22034884538405883 5.020931197315546 0.01566976021321668 0.1555953314915484 1.705796677286367e-05 4.768072735885347 0.25190181048533633 TAS(ph)PPGPPPYGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASPPGPPPYGK 12 0 P54259 P54259 ATN1 Atrophin-1 1 T(0.194)AS(0.806)PPGPPPYGK 89.266 0.007584899999999999 28285000.0 261550.0 286920.0 243300.0 303460.0 330370.0 268530.0 298210.0 292120.0 219990.0 226840.0 True False 305825.24915202835 315403.52141177905 249101.19472038865 286458.12003059394 265636.3700808885 254447.81407995164 269961.38994656556 284452.15952672396 223206.93756980897 267964.29633554776 1.1412910351648888 1.1770356190170477 0.9296059143956308 1.0690159993251043 0.9913125506401637 0.9495586447879958 1.0074528347183873 1.0615300747773126 0.8329726781597309 1.0 18.031681262690505 -5.253613678809849 24.970400196226134 0.9858291492646192 1.1591633489601414 0.5493942248758625 0.0646758789753209 417.74701998188783 1332947.8951648008 0.015781255636399108 0.040149769141835503 5.576816070113615e-06 5.253613678809849 0.17333419969552222 TAS(ph)PPGPPPYGK ddPTM_PC-9_Lapatinib_30min_R1 3 TASPPGPPPYGK 12 0 P54259 P54259 ATN1 Atrophin-1 1 T(0.145)AS(0.855)PPGPPPYGK;T(0.032)AS(0.968)PPGPPPYGK;T(0.4)AS(0.6)PPGPPPYGK 109.72 0.0018131 66044000.0 430800.0 396760.0 475050.0 386975.0 423180.0 434190.0 376800.0 368561.0 433720.0 379970.0 True False 424656.7130009552 395841.3265968608 435993.22274602985 415434.4324107566 398289.38440389105 415620.70584632497 396308.8603034407 385685.6895580813 384869.88632592355 445647.3082218001 0.9528986379282745 0.8882390161321232 0.9783369375340973 0.9322045140772927 0.8937322789923846 0.9326224980572961 0.8892881276109863 0.8654505086029249 0.8636199057537505 1.0 18.765542866257945 -6.197041639651198 5.860275018218275 0.9010978689086919 0.9376685133322168 0.09999186340236066 0.042414748538171225 0.4551954959544193 31.07198975606624 0.012311725570910871 0.015912434049927537 6.352700199790277e-07 6.197041639651198 0.03657064442352487 TAS(ph)PPGPPPYGKR ddPTM_PC-9_Lapatinib_30min_R1 2 TASPPGPPPYGKR 13 1 P54259 P54259 ATN1 Atrophin-1 1 T(0.123)AS(0.772)PPGPPPY(0.105)GKR;T(0.022)AS(0.978)PPGPPPYGKR 59.75 0.027582 4688900.0 76557.0 42068.0 45557.0 42509.0 39439.0 33999.0 27816.0 26582.6 46471.0 27510.0 True False 75465.28314116558 41970.59413065022 41811.47931510551 45635.25366586701 37119.275560057315 32544.942025539993 29256.17637526671 27817.72464055239 41236.94661867564 32265.066845229172 2.338916063715645 1.3008060492165427 1.2958745604237887 1.4143858397930082 1.1504478121217934 1.0086742476515962 0.9067446385778256 0.8621623123854033 1.2780679121628127 1.0 14.977685393941567 -1.6972899922466909 0.7845600808825745 1.0524061495421586 199.99999999576923 0.8296595118875875 0.16595432438011917 137.92161072358965 0.6993416772316348 0.06346681802796696 48426.87423285607 0.020077517251929505 1.6972899922466909 198.94759384622708 up TAS(ph)PPPPPK ddPTM_PC-9_AZD4547_30min_R2 4 TASPPPPPK 9 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 T(0.015)AS(0.985)PPPPPK;T(0.013)AS(0.987)PPPPPK;T(0.082)AS(0.918)PPPPPK;T(0.001)AS(0.999)PPPPPK 105.86 0.0026076999999999997 961870000.0 468224.0 400846.0 515307.0 717768.0 634688.0 545627.0 492351.0 581415.0 517018.0 559802.0 True False 617109.4923357851 530411.6305292381 508473.6924843879 552297.6770050543 546572.5267123464 511508.8574356593 536169.2851897298 491570.6713375577 544346.5159668329 540203.5023704672 1.142364848853898 0.9818737349938286 0.9412632281226506 1.022388182567341 1.0117900463694354 0.9468817865695188 0.9925320417897424 0.9099731289791648 1.007669357155564 1.0 19.043143467923315 -4.762084421370147 6.637573494642654 0.9768437877224759 1.1466319077380922 0.671809107433461 0.03415262826307854 0.06681445745044663 14.704599742470867 0.008355407952541343 0.051359389308463364 1.7294801374102654e-05 4.762084421370147 0.16978812001561627 TAS(ph)PPPPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TASPPPPPK 9 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 T(0.008)AS(0.992)PPPPPK;T(0.012)AS(0.988)PPPPPK;T(0.001)AS(0.999)PPPPPK;T(0.006)AS(0.994)PPPPPK 95.573 0.0053826 596501000.0 417793.0 404720.0 401715.0 451291.0 530273.0 449934.0 442997.0 446489.0 412383.0 338475.0 True False 488517.1031121127 444897.9268987016 411293.40911262087 426006.62837516336 426369.81224658136 426338.6689764608 401033.11713946174 434769.1368442003 418413.3212230123 399837.83813337336 1.2217880763679967 1.1126959093608784 1.0286505425117527 1.065448508735336 1.0663568366542582 1.066278946902088 1.0029894094357565 1.0873636644143094 1.0464575418283517 1.0 18.609055480547163 -4.847435324220328 2.4725260584504656 1.0493115826501096 1.2469337180156934 0.7964071944400212 0.027396426418810547 0.18582797502522458 1.616049544692436 0.006858525042612743 0.0744936655726407 1.4209038002104444e-05 4.847435324220328 0.19762213536558382 TAS(ph)PPPPPK ddPTM_PC-9_Lapatinib_30min_R1 4 TASPPPPPK 9 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 T(0.004)AS(0.996)PPPPPK;TAS(1)PPPPPK;T(0.001)AS(0.999)PPPPPK;T(0.157)AS(0.843)PPPPPK 121.5 0.0016128 911760000.0 906048.0 803923.0 915960.0 826310.0 939452.0 868384.0 779902.0 790522.0 855837.0 698198.0 True False 893127.5893711454 802061.5656863835 840653.3045078483 887079.5938893552 884195.280393697 831245.2406219739 820281.5094702067 827252.5380624448 759443.6246968551 818880.5940096442 1.0906688910503437 0.9794609513935281 1.0265883825523257 1.0832832043873148 1.079760940559404 1.015099450033107 1.00171076890918 1.010223644465437 0.9274168056398109 1.0 19.643293573447004 -7.4727827835015335 1.460562233269993 0.9721492602450859 1.0468756977343538 0.42461691811353297 0.03689857682820726 0.44398842577640496 1.8201434231103573 0.02571204741583806 0.012682953325069303 3.3667992092192374e-08 7.4727827835015335 0.074726437489268 TAS(ph)PPPPPKR ddPTM_PC-9_AZD4547_30min_R2 3 TASPPPPPKR 10 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 T(0.166)AS(0.834)PPPPPKR;T(0.021)AS(0.979)PPPPPKR;T(0.255)AS(0.745)PPPPPKR 116.84 0.00046169 722213000.0 465001.0 424468.0 588765.0 713854.0 616245.0 596704.0 430123.0 583613.0 464156.0 584790.0 True False 612861.6453783519 561668.9800758514 580957.591407783 549285.9892343584 530690.0189129941 559392.0045512539 468403.1137413394 493429.0209425721 488690.3385667448 564316.6800962227 1.0860243317171694 0.9953081308531944 1.0294886043572606 0.9733647942866028 0.9404117185097296 0.9912732057749399 0.8300359182391546 0.8743831935969651 0.865985989433127 1.0 19.10614546789016 -6.202427151143243 0.7981536133587024 0.8895323800115226 1.0515333061839423 0.5285962519249581 0.052351412276200104 0.5258677024087193 0.7120795112918948 0.027811512052165643 0.051420666448617494 6.274409345337011e-07 6.202427151143243 0.16200092617241968 TAS(ph)PPPPPKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TASPPPPPKR 10 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 T(0.067)AS(0.933)PPPPPKR;T(0.295)AS(0.705)PPPPPKR;T(0.05)AS(0.95)PPPPPKR;T(0.157)AS(0.843)PPPPPKR;T(0.036)AS(0.964)PPPPPKR 122.18 0.00025695 643189400.0 341807.0 353856.0 373853.0 417577.0 430112.0 397219.0 380877.0 357774.0 355127.0 303870.0 True False 399668.1741040237 388984.4851271659 382767.0733653974 394181.51449290034 345834.64118482615 376388.1363759147 344797.573249314 348382.811592888 360320.06054072286 358959.22556640423 1.1134082804903107 1.0836453207558174 1.0663246577976275 1.0981233700594228 0.9634371163998676 1.0485540127350377 0.9605480196399898 0.9705358903735443 1.003791057249389 1.0 18.453460451036648 -6.255064882645055 24.997654619540384 0.9910118099795084 1.0881767809230571 0.7739551475018296 0.026261161184920428 246.36444659179233 966120.474163236 0.007774168169348269 0.009793718102977423 5.558212125945774e-07 6.255064882645055 0.0971649709435487 TAS(ph)PPPPPKR ddPTM_PC-9_Lapatinib_30min_R1 2 TASPPPPPKR 10 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 T(0.421)AS(0.579)PPPPPKR;T(0.026)AS(0.974)PPPPPKR 98.182 0.002227 421895000.0 316831.0 253090.0 293100.0 235243.0 287203.0 306164.0 224363.0 220588.0 296653.0 241900.0 True False 312312.93184030993 252503.985654803 269002.44939871895 252543.55496764384 270310.28420282307 293070.07942314236 235979.41832340992 230837.32377608554 263240.8152454215 283712.0926885102 1.100809376437827 0.890000786579193 0.9481529209756276 0.8901402565343363 0.9527626462492698 1.032984095411493 0.831756644869183 0.813632304455643 0.9278448893415189 1.0 18.11406811849264 -7.273111259042179 24.997592740337126 0.8777778206253998 0.9602548590192513 0.1737837284708731 0.07666614051059796 1232.7660127269096 2640197.879878783 0.031222130854978984 0.021249872408288073 5.331982814342402e-08 7.273111259042179 0.08247703839385156 TAS(ph)PSTSSIDSATDTR ddPTM_PC-9_Lapatinib_30min_R1 1 TASPSTSSIDSATDTR 16 0 Q96P50-4;Q96P50-1;Q96P50 Q96P50-4 ACAP3 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 1 T(0.004)AS(0.414)PS(0.13)T(0.279)S(0.086)S(0.086)IDSATDTR 125.33 3.214e-05 3706300.0 5979.0 6618.6 8488.8 8052.5 7320.2 9247.3 5763.8 6009.4 8908.2 4820.1 True False 5893.738363585683 6603.2750383455705 7790.883631715602 8644.70771235254 6889.640228066929 8851.814535509153 6062.221361510002 6288.618662393274 7904.86470849533 5653.247862620469 1.0425402364816423 1.1680498005415123 1.3781252513673206 1.529157737716002 1.2187047862559754 1.5657927532308906 1.0723431041461464 1.1123904019800555 1.3982873032620156 1.0 12.464864236977213 TAS(ph)QEGCQELTQEQR ddPTM_PC-9_AZD4547_30min_R2 1 TASQEGCQELTQEQR 15 0 A0A0C4DG33;O43933-2;O43933 A0A0C4DG33 PEX1 Peroxisome biogenesis factor 1 1 T(0.226)AS(0.72)QEGCQELT(0.054)QEQR 106.76 0.00090966 4728000.0 9441.8 13688.0 16203.0 24609.0 18694.0 20624.0 19575.0 19633.0 16163.0 17722.0 True False 12444.09599835982 18112.378316570976 15988.137633147875 18935.775255259923 16098.660781928436 19334.37801969668 21317.137078200256 16599.170971458025 17017.343182581513 17101.558174156977 0.7276586069896671 1.0591069031324585 0.9348936202379706 1.1072543836312367 0.9413563733774816 1.1305623629613955 1.2465026204696161 0.9706233082633292 0.9950755954096203 1.0 14.061840158913041 -4.335062214046246 1.88677236203467 1.0507006954642604 8.888450413900064e-13 0.494174937800253 0.0938868284132845 3.617546134113959 4.255541160047523 0.025862404525483045 10.225071406580954 4.623147886123074e-05 4.335062214046246 -1.0507006954633715 TAS(ph)QGPQTDSVIQNSENIK ddPTM_PC-9_AZD4547_30min_R2 1 TASQGPQTDSVIQNSENIK 19 0 Q9NZN5-2;Q9NZN5;E9PMR6 Q9NZN5-2 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 T(0.066)AS(0.934)QGPQTDSVIQNSENIK 256.66 1.6095999999999996e-65 13800000.0 32950.0 27852.0 42720.0 54390.0 62700.0 62122.0 48350.0 51366.0 49041.0 58268.0 True False 43427.41459742379 36854.614324454604 42153.504887247866 41851.22581712327 53995.18728078061 58237.50151956926 52653.056333638946 43428.564973254855 51633.20714081422 56228.05505539888 0.7723442426496308 0.6554488553470945 0.7496881200268439 0.7443121725602853 0.9602890803813446 1.035737435025817 0.9364196624222969 0.7723647017572761 0.9182819339908241 1.0 15.779002524054704 -6.221897669571699 6.219203534080351 0.9307217273282973 0.7250423082269516 0.6719144492790596 0.07067176212028273 0.1391322674041087 15.448824091607197 0.022956876705989993 0.02936036070288549 5.999324183903947e-07 6.221897669571699 -0.20567941910134568 TAS(ph)QGPQTDSVIQNSENIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASQGPQTDSVIQNSENIK 19 0 Q9NZN5-2;Q9NZN5;E9PMR6 Q9NZN5-2 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 T(0.116)AS(0.863)QGPQT(0.019)DS(0.002)VIQNSENIK 127.71 6.462e-05 6425000.0 11064.0 12276.0 14830.0 25917.0 44989.0 51018.0 62203.0 65375.0 58802.0 53328.0 True False 12936.916676039145 13494.680150742375 15183.603443088188 24464.9545140477 36173.72840623873 48342.52626794394 56310.68152927881 63658.97552053819 59661.86800754531 62995.94425578427 0.20536110425634713 0.21421506273403143 0.24102509490829696 0.38835761259029516 0.5742231318791173 0.7673910890462625 0.8938778868150449 1.0105249833554648 0.9470747476265851 1.0 15.942971328949046 -6.5616130117357425 0.9153901895803517 0.9991565507668465 0.18534255196552712 0.995214415835076 0.022270632743962217 0.03363325903064726 0.06161141854702125 0.012248421119184543 0.014026113648551787 2.744018204514269e-07 6.5616130117357425 -0.8138139988013193 down TAS(ph)QGPQTDSVIQNSENIK ddPTM_PC-9_Lapatinib_30min_R1 1 TASQGPQTDSVIQNSENIK 19 0 Q9NZN5-2;Q9NZN5;E9PMR6 Q9NZN5-2 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 T(0.118)AS(0.829)QGPQT(0.052)DSVIQNSENIK 142.97 0.00022275 8602500.0 32301.0 32374.0 31409.0 37576.0 62759.0 77187.0 82950.0 75256.0 98195.0 81476.0 True False 31840.381816722074 32299.03999205264 28826.67326224617 40339.46438986137 59067.63900894132 73885.89194168526 87244.74512253281 78752.66849553514 87135.24506080906 95559.01804005404 0.3332012244346841 0.3380009616519326 0.30166355675780726 0.4221418890360812 0.6181273125282934 0.7731964335455563 0.9129933198556283 0.824125970638643 0.9118474304987718 1.0 16.544104408353917 -6.532549506023696 1.2275996990212796 0.9081807180352526 0.31410621519953624 0.9728992320502212 0.042842716356826335 0.06534767310173728 0.2061107951178559 0.018949332898029546 0.02119728640033943 2.9339350402625406e-07 6.532549506023696 -0.5940745028357164 down TAS(ph)TDLK ddPTM_PC-9_AZD4547_30min_R2 2 TASTDLK 7 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 T(0.093)AS(0.881)T(0.025)DLK;TAS(0.996)T(0.004)DLK 104.01 0.010412000000000001 68982000.0 391770.0 433080.0 402430.0 670450.0 634120.0 631370.0 627460.0 541190.0 659520.0 743640.0 True False 516344.71067777555 573064.6406590116 397093.5152569095 515888.110849242 546083.3837079514 591890.3340911496 683302.7244489146 457561.52080901404 694380.8807632348 717605.3899463991 0.719538506694248 0.7985790640477437 0.5533591592540436 0.7189022240869397 0.7609800474725261 0.8248131109151233 0.9521984283032675 0.6376227481278968 0.9676360998558009 1.0 19.452831200841892 -6.627588365201838 2.163483371441642 0.8619579255434686 0.695477146650923 0.3735099310914447 0.11002147719308894 0.37992354310224685 3.6286310763621397 0.04047120545993872 0.04070178281722123 2.3572825146695806e-07 6.627588365201838 -0.16648077889254564 TAS(ph)TDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TASTDLK 7 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 T(0.008)AS(0.988)T(0.004)DLK;T(0.023)AS(0.975)T(0.003)DLK 114.89 0.0084641 108936000.0 382640.0 456580.0 406930.0 570660.0 706750.0 531530.0 491710.0 472240.0 476280.0 435640.0 True False 447413.3945155102 501906.24496790045 416632.7544906186 538687.7703046816 568267.4109473255 503655.6310949123 445131.6691278821 459844.2003796403 483244.6939667652 514618.0834756573 0.8694086136533404 0.9752985001578202 0.8095960244473732 1.0467719413714751 1.1042507622532973 0.9786978873600668 0.8649747908614602 0.8935640140624636 0.939035586746193 1.0 18.97314262813167 -5.765584228231865 24.999928896426635 0.9718071729244677 0.8938207990174426 0.22876319329656136 0.07545917805715244 201.14166742065964 1213209.6923526945 0.02358523057312039 0.036455836744117405 1.7155989500109413e-06 5.765584228231865 -0.07798637390702512 TAS(ph)TDLK ddPTM_PC-9_Lapatinib_30min_R1 2 TASTDLK 7 0 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 T(0.061)AS(0.936)T(0.004)DLK;T(0.276)AS(0.722)T(0.002)DLK 113.66 0.008990100000000001 121225000.0 1148150.0 1289950.0 1029810.0 927680.0 1170010.0 890890.0 870980.0 866460.0 1063980.0 780270.0 True False 1131777.1704550795 1286963.2000292914 945142.9969815562 995904.6818497598 1101192.3121281634 852788.7114660237 916075.0826621304 906718.8947677449 944143.3681938949 915138.6298555791 1.236727566219873 1.4063040921268848 1.0327866906139807 1.0882555378597958 1.2033065550975004 0.9318683351839326 1.0010232906534597 0.9907994976792064 1.0316943656316782 1.0 19.80363078117321 -5.330612813767182 0.7047802630919381 0.9999910185145506 1.403278062167792 0.5735215872696723 0.09046683152213393 1.1600517536064032 0.7124386894905063 0.04276036031147806 0.33304889644789354 4.670756063119018e-06 5.330612813767182 0.4032870436532414 TASAETPRPSQLAQPSPFQLSAS(ph)VPK ddPTM_PC-9_AZD4547_30min_R2 2 TASAETPRPSQLAQPSPFQLSASVPK 26 1 O60292;M0R2Q7 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 TASAETPRPSQLAQPS(0.238)PFQLS(0.34)AS(0.423)VPK;TASAETPRPSQLAQPSPFQLS(0.136)AS(0.864)VPK 100.15 1.2299e-09 24281000.0 39862.0 36827.0 50854.0 62978.0 64236.0 52419.0 53070.0 50463.0 51234.0 60175.0 True False 52537.28681889248 48730.60755876383 50179.642732586704 48459.39510040059 55317.94019407058 49141.231643448395 57793.12718978734 42665.102874379154 53942.12464371595 58068.29156584451 0.9047500004252692 0.8391947867711497 0.8641487699993249 0.834524209231328 0.9526359171656485 0.8462661862150087 0.9952613660805715 0.7347401089973613 0.9289428565769007 1.0 15.825462968510987 -6.223738659239192 24.981905303575598 0.8974904037567218 0.8593712097628035 0.07954601098415681 0.07504383249892282 1849.002121354317 1225216.9073122798 0.021136746866978057 0.027286776127880143 5.973946662630595e-07 6.223738659239192 -0.03811919399391839 TASAETPRPSQLAQPSPFQLSAS(ph)VPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TASAETPRPSQLAQPSPFQLSASVPK 26 1 O60292;M0R2Q7 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 TASAETPRPSQLAQPSPFQLS(0.022)AS(0.978)VPK;TASAETPRPSQLAQPSPFQLS(0.049)AS(0.951)VPK 89.652 3.0401e-07 12696600.0 11170.7 10550.0 10167.5 13106.0 22580.6 32931.0 33047.0 40029.0 33368.6 28781.0 True False 13061.678878618071 11597.33427747898 10409.931760458472 12371.7133102253 18156.09352619339 31204.040388287707 29916.54892043915 38978.28116423132 33856.552647810895 33998.767469729355 0.38418095274328623 0.3411104325415506 0.30618556304215755 0.36388711212076724 0.5340221095473118 0.9177991648100208 0.8799303959202406 1.1464615944956078 0.9958170594847275 1.0 15.053194825984779 -6.71272136341645 1.6789207621784883 1.0260296004910863 0.3360169544983249 0.9597436039000287 0.06278123818331355 0.06330156153051507 0.3693278944404857 0.02598362906567283 0.02458553172481234 1.9376647407855208e-07 6.71272136341645 -0.6900126459927614 down TASAETPRPSQLAQPSPFQLSAS(ph)VPK ddPTM_PC-9_Lapatinib_30min_R1 2 TASAETPRPSQLAQPSPFQLSASVPK 26 1 O60292;M0R2Q7 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 TASAETPRPSQLAQPS(0.001)PFQLS(0.064)AS(0.935)VPK;TASAETPRPSQLAQPS(0.009)PFQLS(0.342)AS(0.65)VPK 93.494 2.824e-08 12765700.0 29744.6 20281.1 21599.0 23135.7 45356.0 42182.0 38009.0 34176.0 50949.0 41492.0 True False 29320.436549508406 20234.140359017074 19823.21359455109 24837.176556432747 42688.249253326896 40377.97419104468 39976.92004053467 35763.941725621975 45210.58710324517 48663.83691538526 0.602509756895857 0.4157941839686704 0.40734999233658664 0.5103826194309059 0.8772068122690679 0.8297326464670736 0.8214913285618013 0.7349182471535668 0.9290386859929589 1.0 15.570562454050387 -6.224679993680985 5.375996732863179 0.8486692706209966 0.46987086243663057 0.8330660981651596 0.08342323920583455 0.07660313686457633 6.034448761956466 0.02453477817401585 0.031235418301645706 5.961012140259025e-07 6.224679993680985 -0.37879840818436605 TASDTDSSYCIPT(ph)AGMSPSR ddPTM_PC-9_AZD4547_30min_R2 2 TASDTDSSYCIPTAGMSPSR 20 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 TASDTDSSYCIPT(0.943)AGMS(0.056)PS(0.001)R;TASDTDSS(0.001)Y(0.001)CIPT(0.75)AGMS(0.242)PS(0.007)R 102.03 0.00093466 20381900.0 46556.0 52350.0 72538.0 107748.0 90335.0 74562.0 68279.0 90278.0 62184.0 77403.0 True False 61359.83957504285 69271.11373995407 71576.09872451275 82908.36329000551 77793.54454560328 69899.62635301691 74355.69872605018 76327.60948206007 65470.91928884788 74693.14452963974 0.8214922528893402 0.9274092579201282 0.9582686493552285 1.109986248565366 1.0415084949962607 0.9358238536239337 0.995482238621569 1.021882395803697 0.8765318383786573 1.0 16.18868821550968 -4.885818676697295 1.9348667973497276 0.9975899243624019 0.7922157456214879 0.4460034156179312 0.05900628255423162 0.5817343745260699 2.7997836518438466 0.016657286877926794 0.20147403938870143 1.3007125282044873e-05 4.885818676697295 -0.20537417874091402 TASDTDSSYCIPT(ph)AGMSPSR ddPTM_PC-9_Lapatinib_30min_R1 1 TASDTDSSYCIPTAGMSPSR 20 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 TASDTDS(0.001)S(0.003)Y(0.011)CIPT(0.725)AGMS(0.205)PS(0.055)R 83.87700000000001 0.0031075 6213000.0 28472.0 30665.0 35450.0 35504.0 32944.0 29646.0 25595.0 29004.0 36875.0 26398.0 True False 28065.984058874667 30593.997076551987 32535.43784095729 38115.08259787202 31006.298690396015 28378.109688201366 26920.18386270317 30351.631724307663 32721.749189035418 30960.859126876036 0.9064988779497908 0.9881507793817779 1.0508570743346852 1.2310731572944515 1.0014676454336675 0.9165801753726958 0.8694908546428126 0.9803226583580323 1.0568747157481433 1.0 14.918157884652143 -6.521065346056533 24.857716387280124 0.9576481267295994 1.0500805140387992 0.14768236307246552 0.08878171601639498 120.6212503684832 1653485.4016981465 0.031402347594345716 0.031878471092777014 3.0125527067746185e-07 6.521065346056533 0.09243238730919978 TASDTDSSYCIPTAGMS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 2 TASDTDSSYCIPTAGMSPSR 20 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 TASDTDSSYCIPTAGMS(0.886)PS(0.114)R;TASDTDSSYCIPTAGMS(0.991)PS(0.009)R 173.59 2.884e-09 19265400.0 43097.0 43164.0 59870.0 84236.0 75380.0 60689.0 59311.0 65302.0 47757.0 67918.0 True False 56800.94952671239 57115.91888197467 59076.08468163696 64816.69163322662 64914.78815351263 56894.10723610216 64589.564099368334 55211.076390676506 50281.337522152186 65540.21149263026 0.866658013959864 0.8714637560850278 0.9013715906040345 0.9889606724951597 0.9904574104221809 0.8680793964557114 0.9854952040646249 0.8424000340140003 0.7671830221024862 1.0 16.000092707890552 -9.936764611656269 9.321400612125746 0.9999994450382795 0.9027775107277064 0.1616853082609896 0.06890568121411911 0.0 0.0 0.07032705833857673 0.017056817051113365 1.1567390268265676e-10 9.936764611656269 -0.09722193431057313 TASDTDSSYCIPTAGMS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TASDTDSSYCIPTAGMSPSR 20 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 TASDTDSSYCIPT(0.01)AGMS(0.989)PS(0.001)R;TASDTDSSYCIPT(0.001)AGMS(0.811)PS(0.188)R;TASDTDSSY(0.001)CIPT(0.038)AGMS(0.862)PS(0.099)R 141.37 5.696e-05 27823600.0 54194.0 57108.0 68113.0 81889.0 106286.0 83553.0 72621.0 78286.0 70420.0 67802.0 True False 63367.97381970943 62777.304826376276 69737.07223999109 77301.02481772004 85460.02128043491 79171.33359334971 65741.81314949058 76231.07545087351 71449.75927844884 80093.96587966342 0.7911703849815124 0.7837956846923471 0.8706907127656413 0.9651291950489802 1.0669969996096047 0.988480626771561 0.8208085643837875 0.9517705187105646 0.8920741842874655 1.0 16.289405936498028 -5.507671350829672 2.99721642263866 0.9531248093999588 0.788463044726097 0.5435076279067983 0.0617262503978915 0.2137232101290618 3.86608314506984 0.018784377697565205 0.04108574509225407 3.1069098300246234e-06 5.507671350829672 -0.16466176467386184 TASDTDSSYCIPTAGMS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 7 TASDTDSSYCIPTAGMSPSR 20 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 TASDTDSSYCIPT(0.003)AGMS(0.995)PS(0.002)R;TASDTDSSYCIPT(0.001)AGMS(0.953)PS(0.046)R;TASDTDSSYCIPTAGMS(0.991)PS(0.009)R;TASDTDSSYCIPTAGMS(1)PSR;TASDTDSSYCIPTAGMS(0.995)PS(0.005)R;TASDTDSSYCIPT(0.005)AGMS(0.948)PS(0.047)R;TASDTDSSYCIPTAGMS(0.999)PS(0.001)R 334.98 1.1305999999999995e-199 35225800.0 132571.4 159552.7 179672.9 168765.1 161291.1 168202.1 130489.90000000001 149064.40000000002 183902.0 129919.1 True False 130680.907525383 159183.26552603836 164900.88771945104 181176.6484378699 151804.27460850327 161008.48828124604 137246.02853001552 155990.4762103462 163189.02018608793 152375.4433286807 0.8576244614658701 1.0446779484189777 1.0822012006472224 1.18901474200842 0.996251569756254 1.0566564058090613 0.9007096257234156 1.023724511001866 1.0709666637955688 1.0 17.21727089273699 TASES(ph)ISNLSEAGSIK ddPTM_PC-9_AZD4547_30min_R2 1 TASESISNLSEAGSIK 16 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 T(0.026)AS(0.097)ES(0.877)ISNLSEAGSIK 199.05 4.3398e-12 54212000.0 26381.0 32869.0 32538.0 45022.0 36574.0 36114.0 36381.0 38483.0 36111.0 43182.0 True False 34769.609241111895 43493.26146167238 32106.524860048467 34642.87348296606 31496.331413194104 33855.78587099134 39618.83852066426 32536.336601366016 38019.7537379324 41670.21132357785 0.8343996379360462 1.0437494814686243 0.7704910496069873 0.8313582384777689 0.7558476526221224 0.8124697426680687 0.9507712407075584 0.7808056539170056 0.9123964705314573 1.0 15.346728795997512 -10.461534296584496 8.097792735419883 1.000000000372373 0.8535988400969076 0.2056048769922546 0.08565792842790716 5.888939849466234e-10 7.607919051314694e-11 0.08268798008270423 0.020054780932350528 3.4551404297860354e-11 10.461534296584496 -0.14640116027546546 TASES(ph)ISNLSEAGSIK ddPTM_PC-9_Lapatinib_30min_R1 1 TASESISNLSEAGSIK 16 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 T(0.024)AS(0.383)ES(0.584)IS(0.009)NLSEAGSIK 147.17 3.0045e-05 44855000.0 56344.0 42301.0 41981.0 41136.0 51986.0 40670.0 48835.0 38300.0 47087.0 42597.0 True False 55540.52422777587 42203.054633465676 38529.48423134631 44161.278665673264 48928.285688408425 38930.6389064005 51363.43734850981 40079.55782102416 41783.56621190807 49959.834693065284 1.1117035228198067 0.8447396772376372 0.7712092017128797 0.8839356442426961 0.9793524335900166 0.7792387453956948 1.0280946216909592 0.8022355972003934 0.8363431638357257 1.0 15.608481082918669 -4.756865703685119 24.97482024661394 0.8756097898997532 1.1117038817253981 0.3813993802975567 0.08810328119519029 140.59304960529744 767621.3680053785 0.021064666222221827 0.1641363572791964 1.7503878750994654e-05 4.756865703685119 0.2360940918256449 TASES(ph)NVYLNSFHYPDHSYK ddPTM_PC-9_AZD4547_30min_R2 1 TASESNVYLNSFHYPDHSYK 20 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;E9PGF6;A0A1W2PRJ2;A0A1W2PRT1 E9PFQ4;A0A1W2PRT1 PHLDB2 Pleckstrin homology-like domain family B member 2 1 T(0.008)AS(0.036)ES(0.938)NVY(0.005)LNS(0.012)FHYPDHSYK 102.92 0.00011635 7509400.0 5455.0 12998.0 27381.0 35680.0 29546.0 39785.0 27170.0 48468.0 31843.0 32342.0 True False 7189.576528951346 17199.349310256403 27017.91004957243 27454.52725050483 25444.047901083643 37297.23766066875 29588.077364735676 40978.3842838398 33526.155971227075 31209.716424138634 0.23036340450023082 0.5510895734045778 0.8656890592147732 0.8796788435178022 0.8152604642509461 1.1950521162640817 0.9480405705273013 1.3130008529057235 1.074221742857517 1.0 14.92970762833661 -5.0612892978935164 0.7029003128151853 1.1044174165593887 1.12850654019575e-20 0.8198613198272308 0.12573236349881733 0.9111937610513479 0.4406455838586275 0.056807163128211303 0.7533918869317481 8.68381778804341e-06 5.0612892978935164 -1.1044174165593887 down TASESISNLS(ph)EAGSIK ddPTM_PC-9_AZD4547_30min_R2 1 TASESISNLSEAGSIK 16 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 TASESIS(0.004)NLS(0.995)EAGSIK 193.8 1.0129e-11 6424200.0 60229.0 53349.0 67053.0 90226.0 76161.0 66801.0 67513.0 64714.0 56253.0 72035.0 True False 79380.56915897547 70593.02095344425 66163.83340834807 69425.78967780404 65587.35978455385 62623.92290989909 73521.5262099889 54713.93827978069 59226.41873722437 69513.07657574763 1.141951602048218 1.0155358449214922 0.9518185162794525 0.9987443096717425 0.943525492114912 0.9008941338060112 1.0576646845701514 0.7871028153984742 0.852018377760708 1.0 16.084996778053394 -1.522878745281429 0.48641215560843853 0.9117197980661151 7.28339383912485 0.4474418034010611 0.07205932147497242 95.70408471217623 1.0548591432108032 0.04169666097962287 618.7070862329443 0.029999999999924608 1.522878745281429 6.371674041058735 TASESISNLS(ph)EAGSIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TASESISNLSEAGSIK 16 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 TASES(0.003)IS(0.002)NLS(0.945)EAGS(0.049)IK;T(0.007)AS(0.032)ES(0.262)IS(0.152)NLS(0.547)EAGSIK 170.48 2.8675999999999998e-05 51512000.0 22279.9 23208.9 24832.4 33632.5 32035.7 30305.7 37364.4 39066.0 33847.3 28387.2 True False 26051.447021916516 25512.926209723424 25424.498593401444 31748.180063036198 25758.534555196653 28716.415741864224 33824.97353716997 38040.55889384846 34342.252729699474 33533.57464704842 0.7768765273644791 0.760817374176631 0.7581803867020563 0.9467579999208533 0.7681416260065755 0.8563481836968968 1.0086897652036388 1.1344021415622247 1.0241154750474009 1.0 15.033318660792915 -7.25893396279317 2.878040862077252 1.0613925670114854 0.8057902226065187 0.7760405668463437 0.06136985938264146 0.12386396224162488 2.0661567231456983 0.0279662883769336 0.019025325111479408 5.5089145654710326e-08 7.25893396279317 -0.25560234440496676 TASESISNLSEAGS(ph)IK ddPTM_PC-9_AZD4547_30min_R2 3 TASESISNLSEAGSIK 16 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 TASESISNLS(0.002)EAGS(0.998)IK;TASESISNLSEAGS(1)IK;TASESISNLS(0.004)EAGS(0.996)IK 252.37 1.9887999999999996e-48 122206000.0 301459.0 273056.0 214918.0 213982.0 269169.0 287399.0 271314.0 290912.0 238253.0 240635.0 True False 397316.6912632706 361316.0120988895 212068.04689507335 164651.75588894406 231799.53054514204 269427.89509711 295460.42039513827 245958.23489272088 250846.5671768606 232210.44189359376 1.7110199180678267 1.55598520528399 0.9132580135748146 0.7090626698190977 0.9982304355260647 1.160274675419508 1.2723821460644207 1.0592040258268265 1.0802553284481777 1.0 17.825073322305215 -5.170988792933805 4.71969822874744 1.0283244289592248 1.6680300640446886 0.7468354733160282 0.1426336630369205 0.12065273157147935 4.526962934044484 0.042369567304625017 0.12118216114016839 6.7454543426906095e-06 5.170988792933805 0.6397056350854637 TASESISNLSEAGS(ph)IK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 TASESISNLSEAGSIK 16 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 TASESISNLSEAGS(1)IK;TASESISNLSEAGS(1)IK;TASESISNLS(0.011)EAGS(0.989)IK;TAS(0.001)ESIS(0.003)NLS(0.209)EAGS(0.786)IK;TASESIS(0.001)NLS(0.124)EAGS(0.875)IK;TASESISNLSEAGS(1)IK 210.57 1.9353000000000002e-17 104228300.0 418319.0 467547.0 392043.0 485783.0 487190.0 373345.0 483121.0 382677.0 360219.0 322625.0 True False 489132.1445231408 513961.9762495223 401390.7919513562 458566.15343973483 391728.616822677 353766.1309636902 437356.28138685814 372632.1342297965 365486.52140760445 381114.35860190605 1.2834261776897915 1.3485767844983836 1.053203016081139 1.2032245521316904 1.0278505860018203 0.9282414135784831 1.1475723008476302 0.9777436242412223 0.9589943626064593 1.0 18.539864437594858 -5.360012266715415 0.740935151197762 1.0009588538020162 1.401711443729814 0.6560769352808159 0.08074565908172861 0.8949784696671863 0.6325088311153096 0.03613924909139093 0.26272066107628594 4.365035029564858e-06 5.360012266715415 0.4007525899277977 TASESISNLSEAGS(ph)IK ddPTM_PC-9_Lapatinib_30min_R1 3 TASESISNLSEAGSIK 16 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 TASESISNLSEAGS(1)IK;TASESISNLS(0.001)EAGS(0.999)IK;TASESISNLSEAGS(1)IK 130.95 1.1958e-05 134771900.0 148075.0 199960.0 186328.0 178386.0 191461.0 195946.0 170435.0 188246.0 171337.0 204278.0 True False 145963.42334637107 199497.00490550563 171008.83108687957 191505.10151825158 180199.64040680908 187565.84635243536 179259.29035514008 196992.59638581012 152039.22280140364 239587.18011667478 0.6092288547128833 0.8326697814480477 0.713764530320868 0.7993128072419899 0.75212555329152 0.7828709627163443 0.7482006769637839 0.8222167658965649 0.6345883061329207 1.0 17.870191188586418 -11.58209788035086 2.3600540541293715 1.3434004640919543 0.7510616396539468 0.5387493311809131 0.07081378750312341 9170327.19664135 2996306.4418277177 16973936.883921623 0.015962059816694126 2.61759299428681e-12 11.58209788035086 -0.5923388244380076 TASESISNLSEAGS(ph)IKKGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TASESISNLSEAGSIKKGER 20 2 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 TASESISNLS(0.003)EAGS(0.997)IKKGER;TASESISNLS(0.274)EAGS(0.725)IKKGER 74.812 0.0007813 17082500.0 50119.0 13110.2 24015.0 86303.0 75838.0 95710.0 64746.0 104655.0 77432.0 64006.0 True False 58603.15680462816 14411.69401370664 24587.608677394684 81467.72270810106 60978.08830763812 90690.79911217449 58612.790159553144 101907.9171411383 78564.2965130479 75609.78112878276 0.775073752757094 0.19060621256342278 0.3251908458181582 1.0774759758838706 0.8064841267530832 1.199458558909262 0.7752011616026317 1.3478139417909847 1.0390758356942318 1.0 16.206285257821396 -5.763633578956922 24.99941594257995 1.0360619992852624 0.4063217817774194 0.636979873381188 0.20898812594600547 32.955772080535084 375486.03948136495 0.05628943098569451 0.08829218132717186 1.7233219554518912e-06 5.763633578956922 -0.629740217507843 TASET(ph)RSEGSEYEEIPK ddPTM_PC-9_Lapatinib_30min_R1 1 TASETRSEGSEYEEIPK 17 1 P48634 P48634 PRRC2A Protein PRRC2A 1 T(0.048)AS(0.056)ET(0.368)RS(0.319)EGS(0.2)EY(0.009)EEIPK 66.335 0.014612 5412200.0 26005.0 29043.0 36568.0 26542.0 31636.0 22434.0 19366.0 21762.0 19991.0 16388.0 True False 25634.16393126706 28975.7527178966 33561.52019656209 28493.98722151644 29775.23267876908 21474.550116208255 20368.676721434254 22773.141966086874 17739.40306543747 19220.6439643626 1.3336787247501125 1.5075328782751063 1.7461184057510877 1.482467875392091 1.5491277365095553 1.1172648614700251 1.0597291515934766 1.1848272101762582 0.9229348974117865 1.0 14.230369052218293 -6.795183872311409 4.976694272776738 1.0627177750949348 1.5345666305885708 0.8096889194251995 0.11327487495316316 0.08401954290773933 4.993265966916514 0.04082299127100482 0.03702373906565796 1.6025667496941831e-07 6.795183872311409 0.471848855493636 TASETRS(ph)EGSEYEEIPK ddPTM_PC-9_AZD4547_30min_R2 1 TASETRSEGSEYEEIPK 17 1 P48634 P48634 PRRC2A Protein PRRC2A 1 T(0.012)AS(0.058)ET(0.314)RS(0.594)EGS(0.022)EY(0.001)EEIPK 54.658 0.025874 3292600.0 17298.0 17762.0 26426.0 32178.0 29135.0 21733.0 20574.0 29831.0 25078.0 29830.0 True False 22798.404179248442 23503.219145158804 26075.57397355835 24759.859245144202 25090.108156707232 20374.03207438266 22405.046142880794 25221.304398184886 26403.57188224829 28785.660779545356 0.7920055875683991 0.8164905202335958 0.9058528888135597 0.8601455924450473 0.8716182806731285 0.7077840675750661 0.7783405187210943 0.8761759749530139 0.9172473782853113 1.0 14.81306270948434 -8.387674242007567 1.8896292728297084 0.9952902850274742 0.8225702253887927 0.5372953743549401 0.05320467290589604 0.27690211972119083 2.0269233588561963 0.05547359591016572 0.015907317130384433 4.095677553750867e-09 8.387674242007567 -0.17272005963868153 TASETRS(ph)EGSEYEEIPK ddPTM_PC-9_Lapatinib_30min_R1 3 TASETRSEGSEYEEIPK 17 1 P48634 P48634 PRRC2A Protein PRRC2A 1 T(0.002)AS(0.002)ET(0.009)RS(0.642)EGS(0.342)EY(0.002)EEIPK;TAS(0.001)ET(0.015)RS(0.983)EGSEYEEIPK;T(0.051)AS(0.051)ET(0.304)RS(0.574)EGS(0.019)EY(0.001)EEIPK 103.73 0.00039452 14263700.0 64221.0 68885.0 75270.0 50007.0 69297.0 61901.0 44423.3 50285.9 46252.4 31685.3 True False 63305.196763310945 68725.50101478181 69081.59115060241 53684.68159846174 65221.0867031439 59253.63852827879 46723.32110912373 52622.36649170337 41042.96765263571 37162.0618869916 1.7034898912719 1.8493457446945063 1.8589278323866116 1.4446098755691972 1.7550448869462278 1.5944658482208771 1.257285487850689 1.4160238646533112 1.104431927847432 1.0 15.181542929483504 -7.554869148445257 0.5288040986240201 0.9862098262086042 1.8058147320247864 0.8145960229270748 0.1249239491473736 0.3554089204614144 0.21581790422433894 0.12194812736046821 0.08688872950505454 2.786960744606357e-08 7.554869148445257 0.8196049058161822 TASFSES(ph)RADEVAPAK ddPTM_PC-9_AZD4547_30min_R2 1 TASFSESRADEVAPAK 16 1 P53396;P53396-2;P53396-3 P53396 ACLY ATP-citrate synthase 1 T(0.166)AS(0.145)FS(0.145)ES(0.544)RADEVAPAK 52.823 0.037328 42535000.0 146010.0 97902.0 169430.0 302060.0 221860.0 164070.0 118760.0 161890.0 141690.0 162690.0 True False 192438.14280333396 129546.90692204353 167183.2474964048 232424.7337804793 191058.5685823603 153810.67696332597 129329.40993139504 136873.62036211195 149179.44413413212 156994.27261898227 1.2257653708831295 0.825169636834127 1.0649002967270704 1.4804663246828322 1.2169779533680856 0.9797215809051663 0.8237842551445902 0.8718383038997722 0.9502222064889184 1.0 17.260352402885495 -6.915639165589986 4.853465643763502 0.9006962940485003 1.154912725179302 0.3635507785407015 0.15851159986218094 0.25706080564067774 10.692039879845842 0.06278972637428785 0.05497042041568635 1.2143974158637563e-07 6.915639165589986 0.25421643113080183 TASFSESR ddPTM_PC-9_Lapatinib_30min_R1 1 TASFSESR 8 0 P53396;P53396-2;P53396-3 P53396 ACLY ATP-citrate synthase 0 125.81 0.015985 9386300.0 34190.0 31391.0 31462.0 29484.0 30980.0 22794.0 19420.0 28115.0 25571.0 23821.0 False True 33702.44433032189 31318.3160681573 28875.315806832084 31652.351715740715 29157.817309023445 21819.153755409236 20425.47257721023 29421.32553885361 22690.924705432535 27938.428110512687 1.2063114000905553 1.120976310631192 1.0335340160374615 1.1329324466837327 1.0436455907142437 0.780972847473803 0.7310888249122548 1.0530773393003787 0.8121761401778499 1.0 14.769963232760606 -6.598803378772247 5.210867028408863 0.8707716893165963 1.1138936913961235 0.5893980554736349 0.0983457684268156 0.14987366282295125 7.2923974952204 0.0332015924142887 0.03328234851365791 2.518817031594167e-07 6.598803378772247 0.24312200207952717 TASGS(ph)SVTSLDGTR ddPTM_PC-9_AZD4547_30min_R2 1 TASGSSVTSLDGTR 14 0 Q92597;E5RJY1;E7ESM1;Q92597-3;Q92597-2 Q92597 NDRG1 Protein NDRG1 1 T(0.096)AS(0.055)GS(0.475)S(0.161)VT(0.135)S(0.079)LDGTR 70.27199999999999 0.027781999999999998 5427400.0 12758.0 12360.0 25279.0 45014.0 32849.0 21305.0 21538.0 29277.0 24218.0 25866.0 True False 16814.778617114796 16355.128287026386 24943.783942994825 34636.71775936728 28288.483365013773 19972.794982042167 23454.84027536537 24752.912368531364 25498.11403797308 24960.439212997648 0.673657160982922 0.6552420070601074 0.9993327332960491 1.3876645945128605 1.1333327560311164 0.8001780261799935 0.9396805911633052 0.9916857695213064 1.0215410802825715 1.0 14.607355700161413 -5.283903850663423 5.716740750638802 1.039630019043404 0.6620647240823384 0.5199445892923189 0.1422819761745453 0.13717232649925773 15.81040208410369 0.04169349079002959 0.09464869556658057 5.201111322469088e-06 5.283903850663423 -0.3775652949610656 TASGSS(ph)VTSLDGTR ddPTM_PC-9_AZD4547_30min_R2 1 TASGSSVTSLDGTR 14 0 Q92597;E5RJY1;E7ESM1;Q92597-3;Q92597-2 Q92597 NDRG1 Protein NDRG1 1 TASGS(0.044)S(0.911)VT(0.044)S(0.001)LDGTR 137.93 7.9034e-05 5710600.0 16045.0 14259.0 27020.0 46821.0 39255.0 26986.0 19698.0 30823.0 29319.0 25496.0 True False 21146.97624326752 18867.94290005739 26661.697145445632 36027.141827239 33805.1208406227 25298.56115397277 21451.08383991768 26060.013592077128 30868.742484075214 24603.392800378417 0.8595146374666776 0.7668837811574991 1.0836593701432737 1.4643160038758913 1.3740024034450549 1.0282549792719506 0.8718750301620086 1.0592040619567034 1.2546538899952218 1.0 14.586569656039618 -5.341557106731477 5.042413131347326 1.1534398066567966 0.8140850511918093 0.377100944553001 0.1700062120305109 0.2319385175619233 10.31488078550283 0.050479589579814806 0.11008341643715215 4.5545229339020116e-06 5.341557106731477 -0.3393547554649873 TASGSS(ph)VTSLDGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASGSSVTSLDGTR 14 0 Q92597;E5RJY1;E7ESM1;Q92597-3;Q92597-2 Q92597 NDRG1 Protein NDRG1 1 TASGS(0.032)S(0.918)VT(0.05)SLDGTR 156.2 0.00034994 5841300.0 39686.0 29703.0 31868.0 29799.0 33699.0 25280.0 21865.0 29274.0 21593.0 19156.0 True False 46404.0559657709 32651.717539711706 32627.853980063028 28129.4586396615 27095.922860295603 23954.27229710344 19793.788911108473 28505.588518366858 21908.75677505741 22628.831161187423 2.050660753762763 1.4429255009739683 1.4418709365787197 1.2430804949355343 1.197407089534967 1.0585731152649807 0.8747154800049255 1.2597022053555795 0.9681788961612355 1.0 14.465874447074798 -1.5228787452803445 0.47296137643758135 1.027602508449331 26.997090774577252 0.8755322399670712 0.11362503449258242 30.95706942193831 0.3531695842261372 0.06576979760347816 787.2332249368428 0.02999999999999952 1.5228787452803445 25.96948826612792 up TASGSS(ph)VTSLDGTR ddPTM_PC-9_Lapatinib_30min_R1 3 TASGSSVTSLDGTR 14 0 Q92597;E5RJY1;E7ESM1;Q92597-3;Q92597-2 Q92597 NDRG1 Protein NDRG1 1 TAS(0.001)GS(0.073)S(0.499)VT(0.073)S(0.354)LDGTR;TAS(0.003)GS(0.045)S(0.902)VT(0.02)S(0.029)LDGTR;TASGS(0.052)S(0.891)VT(0.052)S(0.005)LDGTR 139.64 5.0703e-05 18629800.0 101880.0 91501.0 105135.0 91551.0 82824.0 58985.0 67659.0 55209.0 79634.0 61988.0 True False 100427.17251749613 91289.13505630461 96491.20613283635 98283.96594518324 77952.45515824913 56462.34905075077 71162.0519619705 57774.21169036348 70664.78033680395 72702.5432061819 1.3813433215491258 1.2556525677157095 1.3272053751846151 1.3518642073696556 1.0722108432600308 0.7766213747244782 0.9788110404908035 0.7946656216209358 0.9719712298977089 1.0 16.149718211462847 -6.449288335923639 3.523558023901316 0.8966544367556589 1.3222978448634213 0.8703955685460836 0.07698485963995746 0.07556138775541935 1.812007674314404 0.023682161641948467 0.026371510037871252 3.553952868968927e-07 6.449288335923639 0.42564340810776236 TASGSSVTS(ph)LDGTR ddPTM_PC-9_AZD4547_30min_R2 1 TASGSSVTSLDGTR 14 0 Q92597;E5RJY1;E7ESM1;Q92597-3;Q92597-2 Q92597 NDRG1 Protein NDRG1 1 TASGS(0.002)S(0.013)VT(0.179)S(0.806)LDGTR 98.25299999999999 0.0024995 3352500.0 15710.0 21237.0 22353.0 36535.0 29380.0 28289.0 23198.0 30801.0 22849.0 25933.0 True False 20705.45321170039 28101.444937830074 22056.584614809257 28112.42021012317 25301.09413571507 26520.08435799064 25262.577059519244 26041.41318656744 24056.751492841988 25025.093563390867 0.8273876442959772 1.1229306642409358 0.8813787072938567 1.1233692349206137 1.0110289526640557 1.059739668537615 1.0094898145146514 1.0406120209142131 0.9613051568380362 1.0 14.611087842544292 -4.742027772401199 24.953565665069505 1.0235994010540321 0.827386965715459 0.42659995773233894 0.06814514578145683 1225.4030280797322 1575168.71933105 0.01543401809163439 0.5805660573349124 1.8112242641727252e-05 4.742027772401199 -0.19621243533857313 TASLTSAAS(ph)VDGNR ddPTM_PC-9_AZD4547_30min_R2 1 TASLTSAASVDGNR 14 0 Q9UN36-6;Q9UN36-2;Q9UN36-5;Q9UN36-4;A0A0A0MS87;H0YJT9;G3V578;Q9UN36-3;Q9UN36 Q9UN36-6;Q9UN36-3 NDRG2 Protein NDRG2 1 TASLT(0.019)S(0.033)AAS(0.948)VDGNR 83.292 0.039024 0.0 12275.0 16934.0 20289.0 23463.0 24011.0 22478.0 18807.0 25120.0 22422.0 17983.0 True False 16178.194664138904 22407.584337581302 20019.954603402904 18053.96784973641 20677.48711002908 21072.447106610845 20480.78656601338 21238.281200174475 23607.181144579765 17353.420643599195 0.9322769842559097 1.291248843544073 1.1536604231850542 1.0403694015447964 1.1915510800261715 1.2143108577491557 1.1802161076276172 1.2238671346912928 1.3603762410546574 1.0 14.082932449220186 -6.494700831227338 22.411352774859285 1.2081253737703443 1.1205934886496123 0.11374875528432482 0.11818509655512621 451.31151354286743 358950.7580405134 0.035462697537910474 0.04008074086398379 3.201099464715391e-07 6.494700831227338 -0.08753188512073207 TASLTSAAS(ph)VDGNR ddPTM_PC-9_Lapatinib_30min_R1 1 TASLTSAASVDGNR 14 0 Q9UN36-6;Q9UN36-2;Q9UN36-5;Q9UN36-4;A0A0A0MS87;H0YJT9;G3V578;Q9UN36-3;Q9UN36 Q9UN36-6;Q9UN36-3 NDRG2 Protein NDRG2 1 TASLT(0.001)S(0.004)AAS(0.994)VDGNR 101.3 0.0078863 0.0 8374.5 7718.4 10889.0 9863.2 9457.1 9485.9 7861.9 7401.6 11827.0 7074.7 True False 8255.078094304783 7700.5285190170825 9993.74845275553 10588.572630670662 8900.851971373972 9080.210169712922 8268.950713427857 7745.505356869247 10494.918716168728 8297.552468554804 0.9948810960327173 0.9280481862814052 1.2044212423637923 1.2761079451799944 1.0727081274997041 1.0943239231236142 0.9965529889403726 0.9334686808215257 1.2648210126951618 1.0 13.018470131699557 -7.10342337768628 8.894361215389136 1.0431830380717133 1.1002310549806409 0.03202778986913146 0.12185734446911874 1.393930688419588 109.97259162822925 0.049304375565450795 0.038192956685296854 7.880914616881117e-08 7.10342337768628 0.05704801690892758 TASLVT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 TASLVTR 7 0 Q7L7X3;Q7L7X3-3;Q7L7X3-2 Q7L7X3 TAOK1 Serine/threonine-protein kinase TAO1 1 TAS(0.022)LVT(0.978)R 107.01 0.024380000000000002 5706100.0 34739.0 31311.0 46809.0 66921.0 61020.0 56409.0 38102.0 62706.0 48185.0 52782.0 True False 45785.279383912115 41431.66843002293 46188.28207554274 51493.39736914336 52548.42628186973 52881.7363126973 41493.00418664549 53016.228540531054 50731.96072837286 50934.11824559047 0.8989117896013816 0.8134364519721474 0.9068240241803225 1.0109804418495318 1.0316940410845143 1.0382379853464025 0.8146406694737997 1.040878498865951 0.99603099996268 1.0 15.636344749686744 -5.584380201525363 4.330378341764635 0.988009662428899 0.85627483847653 0.42102066669619154 0.06467061166886867 0.19776497421484823 7.465817129138403 0.018177632831232235 0.033472354375759364 2.6038730007428e-06 5.584380201525363 -0.13173482395236902 TASLVT(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASLVTR 7 0 Q7L7X3;Q7L7X3-3;Q7L7X3-2 Q7L7X3 TAOK1 Serine/threonine-protein kinase TAO1 1 T(0.005)AS(0.356)LVT(0.639)R 93.14299999999999 0.034506 8042200.0 54712.0 49024.0 52534.0 55805.0 77783.0 54627.0 58014.0 50344.0 51571.0 33233.0 True False 63973.66098874311 53890.77873167107 53786.60979630449 52678.426772251056 62541.97951993754 51762.26395466258 52518.493935012455 49022.52334387722 52325.128312253364 39257.879827716766 1.629575037406288 1.3727378800936472 1.3700844271862633 1.341856131900917 1.593106397859565 1.3185190892076015 1.3377822278098028 1.2487307913471792 1.332856703975921 1.0 15.2606946398565 -13.380299733596171 0.11527619182530183 6.066882306027676e-13 1.6212285614216486 0.6658061993751951 0.09538296657541051 72.86384273686234 0.7176288195463665 18.23938660135667 1.1297098955847618 4.1658177527642796e-14 13.380299733596171 1.621228561421042 TASLVT(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 TASLVTR 7 0 Q7L7X3;Q7L7X3-3;Q7L7X3-2 Q7L7X3 TAOK1 Serine/threonine-protein kinase TAO1 1 T(0.002)AS(0.092)LVT(0.906)R 95.815 0.031799 5734800.0 46032.0 39941.0 44425.0 39452.0 38969.0 40495.0 29629.0 29525.0 39644.0 27180.0 True False 45375.575238765065 39848.51906846771 40772.54798545916 42353.43168801396 36676.92003600177 38763.123248455595 31163.04464418957 30896.8392863117 35178.87525017274 31878.026784926533 1.4234122941455343 1.2500309174503237 1.2790173074557547 1.3286089497873408 1.150539218862329 1.215982517047908 0.9775713175234848 0.9692205698541296 1.1035461977466876 1.0 14.960274710392747 -6.802520244909416 1.1086549316720749 1.0060153287250995 1.3192860318265143 0.7845981716070084 0.06896651348600434 0.2196041214230971 0.5718803904548716 0.03698259333271247 0.03208602979432047 1.5757225677369724e-07 6.802520244909416 0.3132707031014148 TASPLPLRPDAPVEKSPEETAT(ph)QVPSLESLTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASPLPLRPDAPVEKSPEETATQVPSLESLTLK 33 2 H0YJG4;Q9HCK8-2;Q9HCK8 H0YJG4 CHD8 Chromodomain-helicase-DNA-binding protein 8 1 T(0.002)AS(0.006)PLPLRPDAPVEKS(0.163)PEET(0.163)AT(0.649)QVPS(0.011)LES(0.005)LT(0.001)LK 59.536 0.00030191 3839200.0 14906.0 11676.0 10760.0 19067.0 17889.0 17477.0 17471.0 20344.0 15998.0 15535.0 True False 17429.291393080202 12835.116116004236 11016.559207527242 17998.737806048037 14383.778867260997 16560.475353499874 15816.020400913632 19809.991556249774 16231.940484757504 18351.372525007675 0.9497541052762708 0.6994090550182904 0.6003125484219134 0.980784286380809 0.7837985331974499 0.9024107232814701 0.8618440053658611 1.0794828304670083 0.8845082547715714 1.0 14.163600347848002 -6.966884799076525 0.8295842231865684 0.9868534387095986 0.7726784807809804 0.2947980710737841 0.11570115658320734 0.7526174054284531 1.087444626309603 0.08274280077062703 0.06377861499501712 1.0792329615230905e-07 6.966884799076525 -0.21417495792861818 TASPPPPPKR ddPTM_PC-9_Lapatinib_30min_R1 1 TASPPPPPKR 10 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 0 96.03399999999999 0.014351 0.0 8191.8 9161.3 7368.0 9259.8 8911.2 8849.9 6722.4 6879.7 8565.1 6469.2 False True 8074.983429807864 9140.087572718596 6762.231481302491 9940.796581787268 8387.060736093279 8471.410407124513 7070.452979044179 7199.355977579631 7600.408243498497 7587.392600332843 1.064263292432453 1.2046414432696733 0.8912457595783096 1.3101729547184873 1.1053943268634019 1.116511409565506 0.9318686077657314 0.9488577113122906 1.0017154303001379 1.0 12.889388474802885 -7.252721410833359 23.899184426087547 0.9663485791323693 1.1176428336827609 0.32812403791792855 0.10137601131813584 395.1549730714622 1083268.7351392615 0.037776003042853355 0.028769405554968007 5.5882855447858435e-08 7.252721410833359 0.15129425455039158 TASQGPQT(ph)DSVIQNSENIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASQGPQTDSVIQNSENIK 19 0 Q9NZN5-2;Q9NZN5;E9PMR6 Q9NZN5-2 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 TAS(0.002)QGPQT(0.998)DSVIQNSENIK 137.09 0.00027254 5341900.0 3601.8 9852.9 10951.0 18178.0 32030.0 38770.0 38775.0 43241.0 42103.0 35356.0 True False 4211.513601207319 10831.030796452389 11212.113371898771 17159.545593871146 25753.95142927885 36736.83294931567 35101.95129331038 42105.96956762664 42718.676723949524 41765.762922058006 0.10083650594547303 0.25932797676089214 0.26845225820063373 0.4108519608726834 0.6166283009684294 0.8795920481058332 0.8404479850832984 1.008145586762141 1.0228156685098706 1.0 15.350033171089601 -6.3757595460030245 0.7955888728576004 1.0183367742381328 0.13127023419558612 0.9802586866574884 0.04735559008966648 0.08128343332982099 0.1129271834752234 0.026951671712530323 0.040168813972594815 4.209596348229908e-07 6.3757595460030245 -0.8870665400425467 down TASQGPQT(ph)DSVIQNSENIK ddPTM_PC-9_Lapatinib_30min_R1 1 TASQGPQTDSVIQNSENIK 19 0 Q9NZN5-2;Q9NZN5;E9PMR6 Q9NZN5-2 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 TASQGPQT(0.922)DS(0.078)VIQNSENIK 214.61 2.7501e-27 8989600.0 23974.0 18256.0 22751.0 21745.0 41790.0 58215.0 54801.0 57945.0 81640.0 56834.0 True False 23632.126363706855 18213.72935364529 20880.500601399683 23344.199839193534 39331.99436230116 55725.280155793116 57638.32763664766 60637.33623862252 72444.84349268742 66657.6811734553 0.35452967981607103 0.2732427686203167 0.313249729570773 0.3502101997584902 0.5900594450615859 0.8359918793272435 0.8646914597383358 0.9096826527888547 1.0868191364799036 1.0 16.024483510712827 -6.653158204608426 1.1538531351131633 0.9857851934060851 0.2897496074503006 0.9698069186363883 0.052039538673993524 0.07415391816725547 0.20955205013730716 0.02620094443284269 0.026265101173465078 2.2225001317720452e-07 6.653158204608426 -0.6960355859557845 down TASQGPQTDS(ph)VIQNSENIK ddPTM_PC-9_AZD4547_30min_R2 1 TASQGPQTDSVIQNSENIK 19 0 Q9NZN5-2;Q9NZN5;E9PMR6 Q9NZN5-2 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 T(0.008)AS(0.074)QGPQT(0.082)DS(0.837)VIQNSENIK 166.62 8.212e-08 12253000.0 22628.0 25056.0 30485.0 40602.0 37891.0 37651.0 33670.0 30368.0 37276.0 43164.0 True False 29823.23330836133 33154.86200321467 30080.748981454868 31241.836194646803 32630.48869626887 35296.67701801782 36666.56477256718 25675.323387217308 39246.33325953775 41652.84149809907 0.7159951694945562 0.7959807977260753 0.7221775970032603 0.7500529392712043 0.7833916612329567 0.8474014196517342 0.8802896382048881 0.6164122893846045 0.9422246321737462 1.0 15.3461272971183 -14.522878744804705 0.15799996508536635 1.8308467296560613 0.719101416603587 0.44220066342077124 0.08121034951094877 127.9006421175764 1.1649231226972208 33.092248743842084 0.34719085723816717 3.0000000032855503e-15 14.522878744804705 -1.1117453130524744 TASRPAPLVQQLS(ph)PSLLPNSK ddPTM_PC-9_AZD4547_30min_R2 2 TASRPAPLVQQLSPSLLPNSK 21 1 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 TASRPAPLVQQLS(0.974)PS(0.026)LLPNSK;TASRPAPLVQQLS(0.998)PS(0.002)LLPNSK 105.52 3.9248e-05 41782000.0 256080.0 227223.0 311420.0 448840.0 352900.0 300050.0 289570.0 342030.0 278770.0 346680.0 True False 337508.1132051067 300668.3911620545 307290.3673217868 345366.8725088732 303905.92649740836 281287.8260672027 315341.16902858 289177.12256750313 293505.21307976515 334542.8387211795 1.0088636615127144 0.8987440661153795 0.9185381713637399 1.0323547018046164 0.9084215571886591 0.8408125761784382 0.942603255935773 0.8643948968476176 0.8773322250798001 1.0 18.3518314364349 -6.4982828105963755 24.854213662290054 0.8962033921158538 0.9583475243760293 0.20403562595370306 0.05525307794466266 1060.4214458129045 1071557.7993447531 0.016621375280139686 0.018754186413965056 3.174805978106637e-07 6.4982828105963755 0.062144132260175566 TASRPAPLVQQLS(ph)PSLLPNSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASRPAPLVQQLSPSLLPNSK 21 1 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 TASRPAPLVQQLS(0.969)PS(0.03)LLPNS(0.002)K 77.83800000000001 0.00055186 15230000.0 123030.0 95703.0 95830.0 122090.0 155510.0 146500.0 150380.0 133650.0 137000.0 108660.0 True False 143856.54904673694 105203.76136090732 98114.95063729868 115249.6931211205 125038.93183787559 138817.2821014893 136134.9177430821 130141.8291138804 139003.36582146396 128359.19784791306 1.1207342477878832 0.8196043846079377 0.7643780288620267 0.8978685988492587 0.9741330106006777 1.0814751449753337 1.0605778162027948 1.0138878342639652 1.0829248558109772 1.0 16.969827153397482 -6.45493155039517 3.050897187135664 1.0488562909067143 0.8853956229284768 0.3672406147072259 0.08989538461792802 0.27030632129249454 4.936516249178035 0.03074481720742865 0.03415818033730922 3.508071606768843e-07 6.45493155039517 -0.16346066797823744 TASRPAPLVQQLS(ph)PSLLPNSK ddPTM_PC-9_Lapatinib_30min_R1 2 TASRPAPLVQQLSPSLLPNSK 21 1 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 TASRPAPLVQQLS(0.852)PS(0.09)LLPNS(0.057)K;TASRPAPLVQQLS(0.882)PS(0.117)LLPNS(0.001)K 71.882 0.0010753 39434000.0 202668.0 159394.0 164536.0 149830.0 181548.0 204517.0 171758.0 164022.0 197846.0 160505.0 True False 199777.91715524058 159024.9329861379 151008.485207327 160848.99801822758 170869.70357710123 195770.28466241236 180650.78882165177 171643.06091175022 175562.5000692584 188248.07539053127 1.061248125595919 0.8447625966758581 0.8021781093594257 0.8544522842240869 0.9076836680673753 1.0399590235187044 0.9596421554211457 0.9117918499600434 0.93261245675444 1.0 17.522275589593086 -6.5359999925027426 24.76944079992506 0.9639496359763768 0.8810624914124365 0.2101933011349576 0.07177287618316582 325.9569058246748 615315.7117564948 0.024399548608640017 0.024413429181821027 2.9107171683145284e-07 6.5359999925027426 -0.08288714456394031 TASRPAPLVQQLSPS(ph)LLPNSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASRPAPLVQQLSPSLLPNSK 21 1 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 TASRPAPLVQQLS(0.352)PS(0.637)LLPNS(0.011)K 94.73 0.00017434 21308000.0 89358.0 74839.0 74966.0 99670.0 111270.0 110570.0 112770.0 104940.0 107570.0 89725.0 True False 104484.54449905173 82268.52132627966 76753.47375013809 94085.81303449963 89467.44225837816 104771.51455263952 102087.60921590209 102185.4361931207 109143.00774755346 105991.43223729101 0.9857829288044179 0.7761808628276569 0.7241479063921346 0.887673758609683 0.8441007010649753 0.9884904123012475 0.9631685039159662 0.9640914745292851 1.0297342477947349 1.0 16.693588124429603 -6.7468156525129865 5.921306827583207 0.9857204650283526 0.8348025832784975 0.5416712516799645 0.06667022522065427 0.13104031002677846 15.535133678171949 0.02326358031229985 0.02225562122665928 1.7913660841820767e-07 6.7468156525129865 -0.1509178817498551 TASRPDDIPDS(ph)PSSPK ddPTM_PC-9_AZD4547_30min_R2 2 TASRPDDIPDSPSSPK 16 1 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 TASRPDDIPDS(0.904)PS(0.096)SPK;TASRPDDIPDS(0.997)PS(0.003)SPK 222.09 2.6275e-22 9808200.0 26907.0 24477.0 27792.0 47436.0 38129.0 36963.0 43042.0 58053.0 50486.0 43375.0 True False 35462.86629963224 32388.7115761768 27423.459921029775 36500.36307889429 32835.44650444793 34651.69776677891 46872.65461659747 49082.24277522805 53154.5868907882 41856.454452322476 0.8472496479611527 0.773804470540377 0.6551787598796042 0.8720366680954986 0.7844774941902897 0.8278698762278037 1.1198429305565958 1.1726325943621496 1.2699256921375202 1.0 15.353162489502113 -7.261712156856629 3.2109840965364436 1.1647647121749605 0.7840762055572935 0.8129765936445732 0.0817165462968998 0.09980554530919078 2.1385396835455386 0.03530241406654008 0.024290608922710673 5.473786361296052e-08 7.261712156856629 -0.38068850661766696 TASRPDDIPDS(ph)PSSPK ddPTM_PC-9_Lapatinib_30min_R1 4 TASRPDDIPDSPSSPK 16 1 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 TASRPDDIPDS(0.961)PS(0.029)S(0.009)PK;TASRPDDIPDS(0.725)PS(0.228)S(0.047)PK;TASRPDDIPDS(0.813)PS(0.094)S(0.094)PK;TASRPDDIPDS(0.787)PS(0.212)S(0.001)PK 191.4 7.0258e-08 23409700.0 157634.0 136143.0 109667.0 112066.0 152795.0 139892.0 157435.0 136020.0 162212.0 183466.0 True False 155386.11025346495 135827.76924810084 100650.60258686209 120307.707481217 143807.89850652788 133909.14526417942 165586.21396462893 142339.98576542322 143941.97639191354 215177.85364692184 0.7221287303498846 0.6312348921881901 0.46775539806255484 0.5591082234634885 0.6683210937799271 0.6223184356318865 0.7695318600785647 0.6614992358785405 0.6689441964046315 1.0 17.71517007613297 -10.884097223032706 0.2781858983183481 1.270379876044051 0.5887342039819008 0.6881072627560134 0.07452525176137927 11.854975606114978 0.6731151164836476 2.4068668998581226 0.10284261755985728 1.3058785158197918e-11 10.884097223032706 -0.6816456720621502 TASRPDDIPDSPS(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASRPDDIPDSPSSPK 16 1 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 TASRPDDIPDS(0.113)PS(0.774)S(0.113)PK 138.98 8.280700000000001e-05 3135200.0 11176.0 9042.6 6862.5 12161.0 14298.0 18028.0 19554.0 19160.0 17931.0 13995.0 True False 13067.876063938313 9940.289567538526 7026.128026176182 11479.658596493951 11496.409539051798 17082.579943519795 17701.703561299582 18657.07030169808 18193.206952880766 16532.182715640956 0.7904507401539246 0.6012690361892808 0.4249969980992784 0.6943825140302342 0.6953957463931937 1.0332924718620555 1.0707420711333024 1.128530371494551 1.1004721678806713 1.0 14.012989593299075 -6.729507920037817 2.509909833347379 1.0871510303831997 0.6138301678328296 0.8444694739654677 0.09157134085915616 0.10581712942610301 1.3656576602868074 0.0355854564032581 0.03358641789389589 1.8641981813786298e-07 6.729507920037817 -0.4733208625503701 TASRPDDIPDSPS(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 3 TASRPDDIPDSPSSPK 16 1 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 TASRPDDIPDS(0.183)PS(0.408)S(0.408)PK;TASRPDDIPDS(0.021)PS(0.49)S(0.49)PK;TASRPDDIPDS(0.017)PS(0.98)S(0.003)PK 226.22 5.2467e-28 19525100.0 68716.1 68049.2 58494.1 59154.1 100007.3 100008.0 99100.0 96112.0 96237.0 105936.0 True False 67736.1958130105 67891.63625833024 53684.94089175569 63504.489846292825 94125.06723591674 95730.89097003454 104230.91309997583 100577.71439410638 85397.77563946298 124246.89644915273 0.5451741471927318 0.546425208183083 0.432082751569782 0.511115300753461 0.7575647354252976 0.7704891929369987 0.8389015426444209 0.8094988065578539 0.6873232095130158 1.0 16.92285028973876 -6.315363503687667 3.4449045128708127 0.8068243093981879 0.5030762686796227 0.7784516094286713 0.07928165109548921 0.11387811019707764 2.7343154782794583 0.02468007996801982 0.029317040832302205 4.83767285747298e-07 6.315363503687667 -0.3037480407185652 TASRPDDIPDSPSS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TASRPDDIPDSPSSPK 16 1 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 TASRPDDIPDS(0.19)PS(0.072)S(0.738)PK;TASRPDDIPDSPS(0.011)S(0.989)PK;TASRPDDIPDS(0.009)PS(0.263)S(0.729)PK;TASRPDDIPDS(0.004)PS(0.215)S(0.781)PK 180.93 4.9318e-29 51859000.0 138643.9 155578.0 114502.3 157043.0 187966.0 193546.0 253496.0 227942.0 222308.0 209856.0 True False 162113.57392815445 171022.75566081752 117232.46908439086 148244.3898502757 151135.4116252208 183396.10704173954 229483.02372789162 221958.76402451284 225558.8339345839 247901.23158081755 0.6539442054982462 0.6898826382194189 0.47289990588922204 0.597997794948215 0.6096597853163532 0.7397950622199757 0.9257034435227424 0.8953515987360181 0.9098737932693575 1.0 17.919405913231856 -7.05493713671627 2.185205084188263 0.9294966552270273 0.5996794587934425 0.8742545499670829 0.058546037043828665 0.11148981875804602 1.0568736223937776 0.027093531555090786 0.020459001135512193 8.811764123534725e-08 7.05493713671627 -0.32981719643358476 TAST(ph)PTPPQTGGGLEPQANGETPQVAVIVRPDDR ddPTM_PC-9_AZD4547_30min_R2 1 TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDR 34 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73;C9JF13;C9K073;C9J6B6;C9J2Z7;C9JSU8;C9JWH7;C9JWW9;C9J556 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 T(0.086)AS(0.225)T(0.6)PT(0.09)PPQT(0.001)GGGLEPQANGETPQVAVIVRPDDR 75.083 3.6630000000000004e-08 9997900.0 21552.0 17667.0 21137.0 37418.0 33440.0 30646.0 18631.0 42867.0 35740.0 33261.0 True False 28405.08769055165 23377.512252985052 20856.70956932954 28791.85820233717 28797.43321641634 28729.700775389065 20289.122906970566 36242.89013566398 37629.143435343874 32096.542513860495 0.8849890195582675 0.7283498602034709 0.6498117222539727 0.8970392430868142 0.897212938246558 0.8951026660576447 0.6321279900540365 1.1291836221927312 1.172373735242486 1.0 14.970130276063372 -7.780015695360923 24.98407477785246 1.1130842332539497 0.8008237245178791 0.6407353783975833 0.1037297015453361 156.6957158495957 210743.70198502153 0.05803042014839222 0.027955863307721866 1.6595269312096695e-08 7.780015695360923 -0.3122605087360706 TAST(ph)PTPPQTGGGLEPQANGETPQVAVIVRPDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDR 34 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73;C9JF13;C9K073;C9J6B6;C9J2Z7;C9JSU8;C9JWH7;C9JWW9;C9J556 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 T(0.013)AS(0.107)T(0.269)PT(0.221)PPQT(0.18)GGGLEPQANGET(0.21)PQVAVIVRPDDR 54.153 0.00079123 16541000.0 4669.1 4194.9 6729.6 6280.7 7357.5 6365.7 4698.7 5482.1 6346.5 4146.2 True False 5459.486411071436 4611.341948871713 6890.059186150125 5928.812741304138 5915.850691255673 6031.871485825604 4253.605120357897 5338.200683765083 6439.305556101603 4897.87323869886 1.114664701392266 0.9414988351345602 1.406745101467856 1.2104871752212092 1.2078407102318642 1.2315287047788104 0.8684596176866114 1.089901764216176 1.3147146204649898 1.0 12.257939720820607 TAST(ph)PTPPQTGGGLEPQANGETPQVAVIVRPDDR ddPTM_PC-9_Lapatinib_30min_R1 2 TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDR 34 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73;C9JF13;C9K073;C9J6B6;C9J2Z7;C9JSU8;C9JWH7;C9JWW9;C9J556 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 T(0.019)AS(0.179)T(0.592)PT(0.198)PPQT(0.012)GGGLEPQANGETPQVAVIVRPDDR;T(0.014)AS(0.131)T(0.401)PT(0.356)PPQT(0.092)GGGLEPQANGET(0.006)PQVAVIVRPDDR 60.391000000000005 0.00030514 248078000.0 123337.0 103459.0 123149.0 92618.0 87157.0 90814.0 85314.0 60777.0 97704.0 69985.0 True False 121578.19176276441 103219.44704200223 113024.16458888726 99429.43668459078 82030.59661725485 86930.09691777363 89731.14147539204 63600.92129734684 86699.54665126823 82081.8140008491 1.4811830518451594 1.2575190777452172 1.3769696243277234 1.2113455080751776 0.9993760203253583 1.0590664689364 1.0931915012802202 0.7748479011037562 1.0562576827355614 1.0 16.324774994279878 -6.043016593660152 0.9850052644398108 0.9664381073513181 1.410013498373656 0.7518242741014005 0.09699816983012846 0.2843671578280558 0.5648283055588309 0.04138414357491965 0.08459340106710038 9.056979950432484e-07 6.043016593660152 0.443575391022338 TASTPT(ph)PPQTGGGLEPQANGETPQVAVIVRPDDR ddPTM_PC-9_AZD4547_30min_R2 1 TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDR 34 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73;C9JF13;C9K073;C9J6B6;C9J2Z7;C9JSU8;C9JWH7;C9JWW9;C9J556 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 T(0.015)AS(0.055)T(0.211)PT(0.548)PPQT(0.169)GGGLEPQANGET(0.001)PQVAVIVRPDDR 57.073 0.00055773 24428000.0 11900.0 4794.8 6503.8 24511.0 18281.0 14764.0 11385.0 26116.0 11375.0 20884.0 True False 15683.952464623459 6344.625332575575 6417.555362492575 18860.367641175017 15742.998703029509 13840.804746062928 12398.24294433255 22080.372285977577 11976.259277477246 20152.85751659488 0.7782495584910726 0.3148250975004954 0.31844394062767706 0.9358656768969085 0.7811794774049253 0.6867911776116966 0.6152101722608425 1.0956447376157692 0.5942710242264845 1.0 14.298696795609693 -6.223283746710529 0.29973043252432335 0.9574557966798577 0.35788169231773787 0.23876133517355558 0.21828227082876117 4.665035721928451 0.6753986715155986 0.2914244620208661 0.9786709294172957 5.980207499720862e-07 6.223283746710529 -0.5995741043621199 TASTPT(ph)PPQTGGGLEPQANGETPQVAVIVRPDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDR 34 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73;C9JF13;C9K073;C9J6B6;C9J2Z7;C9JSU8;C9JWH7;C9JWW9;C9J556 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 T(0.011)AS(0.112)T(0.379)PT(0.401)PPQT(0.097)GGGLEPQANGETPQVAVIVRPDDR;T(0.004)AS(0.03)T(0.091)PT(0.781)PPQT(0.093)GGGLEPQANGET(0.001)PQVAVIVRPDDR;T(0.021)AS(0.093)T(0.246)PT(0.556)PPQT(0.083)GGGLEPQANGET(0.001)PQVAVIVRPDDR 79.373 2.1814e-08 442801000.0 70225.0 59223.0 87956.0 100655.0 134099.0 105080.0 101072.0 90363.0 105552.0 64654.0 True False 82112.705493027 65102.26804882822 90053.20461498748 95015.62667791275 107823.26358772634 99569.41981723226 91497.72846208805 87991.06699751265 107095.49831523439 76375.25839921761 1.075121802715474 0.8523999710552224 1.1790887062440367 1.244062916046201 1.4117564489815315 1.3036868470778524 1.1980022114468598 1.1520886323890203 1.402227639681956 1.0 16.22081773553665 -5.43485247093555 4.648197000051258 1.2558413281240477 0.9661985175845595 0.4415526109434298 0.1237644747956833 0.18027151605404138 6.658857834530817 0.03182360731275386 0.06819100325457612 3.6740708683713434e-06 5.43485247093555 -0.28964281053948815 TASTPT(ph)PPQTGGGLEPQANGETPQVAVIVRPDDR ddPTM_PC-9_Lapatinib_30min_R1 4 TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDR 34 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73;C9JF13;C9K073;C9J6B6;C9J2Z7;C9JSU8;C9JWH7;C9JWW9;C9J556 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 T(0.013)AS(0.083)T(0.21)PT(0.343)PPQT(0.343)GGGLEPQANGET(0.008)PQVAVIVRPDDR;T(0.01)AS(0.084)T(0.255)PT(0.481)PPQT(0.138)GGGLEPQANGET(0.031)PQVAVIVRPDDR;T(0.011)AS(0.045)T(0.167)PT(0.776)PPQT(0.001)GGGLEPQANGETPQVAVIVRPDDR;T(0.004)AS(0.064)T(0.271)PT(0.543)PPQT(0.118)GGGLEPQANGETPQVAVIVRPDDR 98.98 4.976700000000001e-16 284262900.0 68247.0 62104.3 56173.5 55208.8 60793.2 51596.2 52854.0 51771.9 61645.4 46975.1 True False 67273.78526503297 61960.5013090268 51555.13166598062 59269.03932315786 57217.46350002986 49389.55080261669 55590.521503391785 54177.41147661307 54702.245897159715 55094.683444613765 1.2210576603577867 1.1246185191592069 0.9357551117942001 1.075766945511912 1.0385296715163108 0.8964485811460847 1.0089997442180874 0.9833509894122031 0.9928770341724794 1.0 15.749625487127037 -5.036913604395333 3.5807004161356293 0.9930842686594984 1.2111718393985071 0.7148870162048522 0.04751501755078657 0.11868168656820066 3.0823959407359887 0.012514186359886529 0.04870896793649289 9.185153015269549e-06 5.036913604395333 0.21808757073900875 TASTPTPPQT(ph)GGGLEPQANGETPQVAVIVRPDDR ddPTM_PC-9_AZD4547_30min_R2 1 TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDR 34 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73;C9JF13;C9K073;C9J6B6;C9J2Z7;C9JSU8;C9JWH7;C9JWW9;C9J556 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 T(0.003)AS(0.022)T(0.056)PT(0.117)PPQT(0.793)GGGLEPQANGET(0.007)PQVAVIVRPDDR 58.711999999999996 0.00043294 198520000.0 8969.1 6037.9 14702.0 23680.0 20179.0 14624.0 11508.0 18165.0 10603.0 11871.0 True False 11821.087231130618 7989.533097430152 14507.041873883856 18220.941852352997 17377.494164894306 13709.558968194542 12532.189706049983 15358.016640173933 11163.452933546481 11455.399903251193 1.0319227029145999 0.6974468953425728 1.2663933163753252 1.5905984955777628 1.5169696659793033 1.1967769858740234 1.093998447185871 1.3406792228890347 0.9745144672232827 1.0 13.483740202955623 -5.2785817803566735 23.146087987000328 1.2742434489189662 0.8646848678471588 0.3509975952576352 0.20565631072961113 280.0556689244134 378138.65509784245 0.05568856397341474 0.11652874421056321 5.2652405779782e-06 5.2785817803566735 -0.4095585810718074 TASTPTPPQT(ph)GGGLEPQANGETPQVAVIVRPDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDR 34 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73;C9JF13;C9K073;C9J6B6;C9J2Z7;C9JSU8;C9JWH7;C9JWW9;C9J556 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 T(0.001)AS(0.01)T(0.031)PT(0.432)PPQT(0.507)GGGLEPQANGET(0.02)PQVAVIVRPDDR;T(0.001)AS(0.005)T(0.016)PT(0.06)PPQT(0.917)GGGLEPQANGET(0.001)PQVAVIVRPDDR 90.12700000000001 4.9681e-12 66596000.0 41996.0 44976.0 54820.0 56538.0 59334.0 55146.0 47382.0 52860.0 43676.0 40954.0 True False 49105.09334119123 49440.92004397106 56127.11670600776 53370.35915866914 47707.92863268285 52254.046681015294 42893.63394402663 51472.48100979958 44314.67887312593 48378.6360083144 1.0150160771947347 1.0219577095037176 1.160163273234113 1.10318032012099 0.9861362900864695 1.0801058275399673 0.8866234661236602 1.063950645507109 0.9159968641015419 1.0 15.56208247396483 -6.85287677415905 1.616950106297038 0.9750324880499487 1.0713418922837152 0.2803884357306242 0.06689240922596106 0.5016364516105899 2.7073118806676195 0.029943115859685076 0.025314758988299962 1.4032117925687136e-07 6.85287677415905 0.09630940423376655 TATCHS(ph)SSSPPIDAASAEPYGFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TATCHSSSSPPIDAASAEPYGFR 23 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.168)AT(0.168)CHS(0.217)S(0.217)S(0.217)S(0.013)PPIDAASAEPYGFR 77.847 0.00016367 7610900.0 2102.1 1128.0 21546.0 2097.0 5137.1 3105.4 3426.1 2108.7 5839.6 1783.9 True False 2457.9440116324895 1239.9803853077058 22059.73835366004 1979.511888565728 4130.522131980907 2942.5473572557353 3101.5550051840296 2053.348859352335 5924.993102562185 2107.30694865537 1.1663910723593702 0.5884194450641906 10.468213170243619 0.9393562194766237 1.960095151120016 1.396354412978762 1.471809793615054 0.9743947651586947 2.8116421797701583 1.0 11.041184755936419 TATCHSSS(ph)SPPIDAASAEPYGFR ddPTM_PC-9_AZD4547_30min_R2 3 TATCHSSSSPPIDAASAEPYGFR 23 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.002)AT(0.001)CHS(0.004)S(0.018)S(0.539)S(0.437)PPIDAASAEPYGFR;TATCHS(0.012)S(0.048)S(0.893)S(0.048)PPIDAASAEPYGFR;TATCHS(0.001)S(0.003)S(0.784)S(0.212)PPIDAASAEPYGFR 105.82 1.3028999999999998e-06 68904000.0 29847.3 30449.9 58709.0 102440.0 84558.0 58190.0 40570.5 73227.0 50976.0 64789.0 True False 39338.12053759293 40292.23469475121 57930.480300220835 78824.04068222294 72818.58127732443 54551.370101151566 44181.195904527376 61911.44973905951 53670.487290433375 62520.7568302368 0.6292009651196018 0.6444617233946335 0.9265799589969778 1.2607659388425927 1.1647104892707778 0.8725321455924696 0.7066644446498463 0.9902543231709151 0.8584426998567108 1.0 15.932047622196379 -5.287196975846529 4.687059863878153 0.9784091234659776 0.6319014725739156 0.458074226875514 0.14672989918497345 0.18010109356615772 10.482826733545275 0.04360014086632015 0.10290281588156133 5.161821998521655e-06 5.287196975846529 -0.34650765089206204 TATCHSSS(ph)SPPIDAASAEPYGFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TATCHSSSSPPIDAASAEPYGFR 23 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.111)AT(0.111)CHS(0.111)S(0.111)S(0.279)S(0.279)PPIDAASAEPYGFR;T(0.003)AT(0.003)CHS(0.008)S(0.038)S(0.541)S(0.408)PPIDAASAEPYGFR;TATCHSS(0.004)S(0.849)S(0.147)PPIDAASAEPYGFR;TATCHSS(0.001)S(0.552)S(0.447)PPIDAASAEPYGFR 102.46 2.2335e-06 255622000.0 41627.7 50575.4 127772.2 114772.5 151060.0 139866.4 91320.0 101064.6 112489.9 70777.29999999999 True False 48674.44742544779 55596.19147082566 130818.77382676676 108342.16892246566 121460.87739328336 132531.55976327482 82669.50850045387 98411.76133679514 114134.85197751706 83608.66421720161 0.5821698968781459 0.6649572982818606 1.5646557094480187 1.2958246604802877 1.452730749025578 1.5851414563804003 0.9887672440943683 1.1770521902028899 1.3651079471980727 1.0 16.351364833524272 -5.231162384526535 13.010014327911712 1.3138207232394568 0.6232976841799135 0.6575073038919708 0.19622912455514913 1.3025024010416033 557.3890816855254 0.050591734384492326 0.13295966716046523 5.872697288608708e-06 5.231162384526535 -0.6905230390595433 TATCHSSS(ph)SPPIDAASAEPYGFR ddPTM_PC-9_Lapatinib_30min_R1 1 TATCHSSSSPPIDAASAEPYGFR 23 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.145)AT(0.145)CHS(0.145)S(0.145)S(0.415)S(0.006)PPIDAASAEPYGFR 61.345 0.0024660999999999997 7597100.0 9135.3 12869.0 14885.0 10542.0 9869.9 9153.6 6851.5 8590.6 13503.0 8414.3 True False 9005.028946791157 12839.202621169008 13661.212757761603 11317.29384708108 9289.371886969995 8762.121866083788 7206.237145353031 8989.750637527155 11982.149947106303 9868.700543650008 0.9124837567987025 1.3010023522732548 1.3842970203966598 1.1467866308257946 0.9412963587133283 0.8878698697288727 0.730211349861038 0.9109355986398421 1.2141568075866067 1.0 13.268644415680848 -6.201951510829999 3.9089176826190455 0.9277734111651547 1.2159811299607075 0.3441622866508741 0.16027538916807488 0.2437337149146048 7.571577763287531 0.05079358042960025 0.06557404639240202 6.281284857202124e-07 6.201951510829999 0.28820771879555285 TATCHSSSS(ph)PPIDAASAEPYGFR ddPTM_PC-9_AZD4547_30min_R2 3 TATCHSSSSPPIDAASAEPYGFR 23 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TATCHS(0.001)SS(0.225)S(0.774)PPIDAASAEPYGFR;TATCHSS(0.002)S(0.468)S(0.53)PPIDAASAEPYGFR;TATCHSSS(0.019)S(0.981)PPIDAASAEPYGFR 109.4 7.198300000000001e-07 1140265000.0 26098.8 20100.5 196986.9 535705.0 301417.0 246320.0 88161.8 346484.0 120239.7 242692.3 True False 34397.675511236535 26597.593538298872 194374.7249970459 412206.48880974465 259570.45238614155 230917.5714610012 96008.0294079629 292942.85921024147 126595.32506778721 234195.71644678715 0.14687576712809866 0.11356994031247472 0.8299670375961417 1.7600940574991442 1.1083484203910277 0.986002540799969 0.40994784560791653 1.2508463589973584 0.5405535463606638 1.0 17.837355162925412 -5.317075633621627 4.51537271953849 1.0146024590827953 0.12312987852308262 0.4925443356496213 0.34975965846958085 0.16569325906614316 7.136038553587884 0.09597331181149246 0.2188201539662283 4.818638723508951e-06 5.317075633621627 -0.8914725805597127 TATCHSSSS(ph)PPIDAASAEPYGFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TATCHSSSSPPIDAASAEPYGFR 23 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.002)AT(0.002)CHS(0.009)S(0.03)S(0.425)S(0.532)PPIDAASAEPYGFR;T(0.001)AT(0.001)CHS(0.001)S(0.01)S(0.134)S(0.854)PPIDAASAEPYGFR;TATCHSS(0.001)S(0.148)S(0.851)PPIDAASAEPYGFR;T(0.014)AT(0.013)CHSS(0.004)S(0.128)S(0.842)PPIDAASAEPYGFR;T(0.001)AT(0.001)CHS(0.003)S(0.012)S(0.128)S(0.856)PPIDAASAEPYGFR 86.641 1.7144e-05 358978000.0 35585.0 55231.2 172581.0 157820.0 223951.0 230743.0 139850.0 117689.3 173351.0 93399.9 True False 41608.83766421303 60714.18852571541 176695.98555708682 148977.8570593436 180069.40919570465 218642.43088016388 126602.39557368046 114600.08057712052 175885.93042712778 110332.56251679835 0.37712200926972944 0.5502834987311344 1.601485377720512 1.3502619141711807 1.6320604279293225 1.9816672965143463 1.1474617527749797 1.0386786816418991 1.5941434370324608 1.0 16.751499111680985 -5.208720716274437 5.671364099776642 1.4352322859954079 0.43931498962400317 0.6348279205630147 0.28964449641200407 0.13219945795337287 9.706895977928507 0.07681624898295218 0.2080650779279131 6.184139585687761e-06 5.208720716274437 -0.9959172963714047 TATCHSSSS(ph)PPIDAASAEPYGFR ddPTM_PC-9_Lapatinib_30min_R1 6 TATCHSSSSPPIDAASAEPYGFR 23 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TATCHSSS(0.222)S(0.778)PPIDAASAEPYGFR;TATCHSS(0.001)S(0.392)S(0.607)PPIDAASAEPYGFR;TATCHS(0.001)S(0.002)S(0.235)S(0.762)PPIDAASAEPYGFR;TATCHSSS(0.19)S(0.81)PPIDAASAEPYGFR;TATCHS(0.002)S(0.02)S(0.377)S(0.6)PPIDAASAEPYGFR;TATCHSSS(0.006)S(0.994)PPIDAASAEPYGFR 128.25 4.1889e-09 591454000.0 142175.5 76314.30000000002 381157.0 128454.59999999999 250825.8 307969.2 150766.19999999998 185649.6 383495.4 107061.2 True False 140148.0512982063 76137.59892708651 349819.7427685691 137901.57979598385 236072.71958649642 294798.07522726944 158572.13613131773 194275.55816318557 340302.1096664082 125566.5857699179 1.116125364394368 0.6063523863474104 2.7859301949131736 1.0982346852105065 1.8800600345944307 2.347743019527847 1.2628529728591775 1.5471915316640579 2.710132696368453 1.0 16.938093077539513 -5.228647988962625 24.997580048564295 1.822590125401856 0.8612386059490666 0.28737387743377885 0.6095305497314661 789.2381714854894 601650.8962298251 0.14628367414939333 0.3869702682129107 5.9067965294497876e-06 5.228647988962625 -0.9613515194527893 TATDEAYKDPSNLQGK ddPTM_PC-9_Lapatinib_30min_R1 2 TATDEAYKDPSNLQGK 16 1 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 ; 100.4 0.0066879999999999995 1933500.0 37243.0 45082.0 40526.0 37106.0 35906.0 37886.0 41730.0 43883.0 37354.0 42954.0 False True 36711.907990470274 44977.61539882985 37194.10871488391 39834.899021987345 33794.07967391206 36265.70409657953 43890.57521354182 45921.96438276766 33146.79916494179 50378.54166739271 0.7287211335502373 0.8927931200505832 0.7382926834294934 0.7907116344292735 0.670803055337053 0.7198641107162566 0.8712156755809747 0.9115381839742783 0.6579547177800883 1.0 15.620521739817873 -10.522854576222363 5.267031891035586 1.0000011858990279 0.7806147473067688 0.3805587205031924 0.08562373709316803 1.203139296403617e-06 2.2850291032928486e-07 0.08365327505809735 0.020288789763055422 3.000166958583502e-11 10.522854576222363 -0.21938643859225904 TATES(ph)FASDPILYRPVAVALDTK ddPTM_PC-9_AZD4547_30min_R2 2 TATESFASDPILYRPVAVALDTK 23 1 P14618;P14618-2;H3BTN5;P14618-3;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 1 T(0.029)AT(0.079)ES(0.651)FAS(0.215)DPILY(0.025)RPVAVALDT(0.001)K;T(0.03)AT(0.084)ES(0.82)FAS(0.063)DPILY(0.003)RPVAVALDTK 61.522 0.0019809999999999997 15571900.0 51667.0 57700.0 73800.0 83634.0 71575.0 71073.0 56660.0 73444.0 63898.0 59065.0 True False 68096.0312596387 76350.39661500185 72821.36377993664 64353.473432419305 61638.04672443182 66628.7940745687 61702.630235035824 62094.91737522356 67275.51782964761 56997.15232798679 1.1947269026316272 1.3395475650370732 1.2776316150128053 1.129064712954447 1.081423267775542 1.1689846133216828 1.082556368429981 1.0894389428072122 1.1803312109790076 1.0 15.798602221196669 -5.790168407405723 4.9156516606865 1.1076467843635522 1.278808677883143 0.6365036569473036 0.057565843215198295 0.1096649535278409 6.501560844056108 0.015374788087966858 0.02438589284607589 1.6211813261123192e-06 5.790168407405723 0.17116189351959066 TATESFASDPILYRPVAVALDTK ddPTM_PC-9_AZD4547_30min_R2 1 TATESFASDPILYRPVAVALDTK 23 1 P14618;P14618-2;H3BTN5;P14618-3;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 97.62100000000001 1.0151e-05 7427100.0 41032.0 37836.0 47157.0 57549.0 56605.0 49302.0 48253.0 58366.0 45046.0 51279.0 False True 54079.32248138064 50065.747076693435 46531.66736816359 44281.967173186764 48746.372823422455 46219.13814619303 52547.423521552795 49346.8758172525 47427.03959676838 49483.73781811283 1.0928706048876053 1.011761626834252 0.9403426139553128 0.894879189117722 0.98509884201956 0.934026817377469 1.0619129806786451 0.997234202449229 0.9584368862977924 1.0 15.594666859814906 -10.029799177484758 16.102576792688545 0.9999999999896187 0.9839689902147788 0.0037829936459689018 0.056454284799254247 0.0 0.0 0.057228606843545964 0.013879975930757986 9.336859475774902e-11 10.029799177484758 -0.016031009774839955 TATESFASDPILYRPVAVALDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TATESFASDPILYRPVAVALDTK 23 1 P14618;P14618-2;H3BTN5;P14618-3;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ; 131.98 1.2927000000000001e-06 13553900.0 56802.0 65671.0 61834.0 75358.0 77209.0 63213.0 67485.0 62591.0 56559.0 54670.0 False True 66417.45670936155 72190.38287548095 63308.35706675084 71135.9355739325 62080.450699443965 59897.99899987342 61092.33225091044 60948.05257064636 57386.06837588447 64581.23823251809 1.0284326923282632 1.1178228360312157 0.9802902328818105 1.1014953804046757 0.9612768723313991 0.9274829755387602 0.9459764774245083 0.9437423969978584 0.8885873040908855 1.0 15.978827481925743 -6.396641968055066 5.27245836503247 0.938615962508918 1.0554111818860024 0.6172857226981793 0.043540334337990004 0.14333018809945752 5.5629811825365625 0.012835296658979279 0.014548772291912019 4.01197328014868e-07 6.396641968055066 0.11679521937708437 TATESFASDPILYRPVAVALDTK ddPTM_PC-9_Lapatinib_30min_R1 2 TATESFASDPILYRPVAVALDTK 23 1 P14618;P14618-2;H3BTN5;P14618-3;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 ; 193.42 2.3776e-24 29595000.0 61000.0 58009.0 56500.0 59911.0 62994.0 52794.0 62416.0 57621.0 61759.0 61470.0 False True 60130.12881397005 57874.68372456237 51854.78809630708 64317.05479723723 59288.81677096911 50536.12368882489 65647.59507616653 60298.28201580243 54803.051068898654 72095.00759637357 0.8340401203729763 0.8027557753870533 0.7192562956178316 0.8921152371231933 0.8223706293631263 0.700965647604244 0.9105706104325128 0.8363725038130861 0.7601504306056177 1.0 16.13761173935776 -11.196515541026674 2.8386329627442826 1.022570165162621 0.809417601191139 0.4457484811262207 0.06397965948190096 31166074.244159132 29344627.006032944 5095867.242371246 0.015983825956660813 6.360400440319451e-12 11.196515541026674 -0.21315256397148186 TATNDEESPLSVS(ph)SPEGTGTWLHYTSGVGTGR ddPTM_PC-9_AZD4547_30min_R2 2 TATNDEESPLSVSSPEGTGTWLHYTSGVGTGR 32 0 A0A087WWN8;A0A087WZV0;O43314-2;O43314 A0A087WWN8 PPIP5K2 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 1 TATNDEESPLS(0.003)VS(0.496)S(0.496)PEGT(0.006)GTWLHYTSGVGTGR;TATNDEES(0.002)PLS(0.018)VS(0.489)S(0.489)PEGT(0.003)GTWLHYTSGVGTGR 120.4 5.55e-18 9189600.0 8101.799999999999 2589.1 15606.199999999999 29155.0 20027.4 20167.3 13738.2 19141.5 15888.8 16743.7 True False 10678.00387209129 3425.975942389971 15399.251591090067 22433.765190259768 17246.941208087825 18906.235542893162 14960.873185580109 16183.621002911603 16728.649530371913 16157.508159385638 0.6608694711312034 0.21203615734520773 0.9530709462860391 1.388442139032952 1.0674258083582866 1.1701207485951868 0.9259393860735622 1.0016161429886574 1.0353483572684758 1.0 13.979917099712553 -5.391790605526597 5.4189714474068085 1.0863224730407388 0.4434746605727425 0.7254949165768839 0.15674009406329403 0.10432426297575509 4.112592225127883 0.04081373436300317 0.08700925417403098 4.057040979595112e-06 5.391790605526597 -0.6428478124679964 TATNDEESPLSVS(ph)SPEGTGTWLHYTSGVGTGR ddPTM_PC-9_Lapatinib_30min_R1 1 TATNDEESPLSVSSPEGTGTWLHYTSGVGTGR 32 0 A0A087WWN8;A0A087WZV0;O43314-2;O43314 A0A087WWN8 PPIP5K2 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 1 TATNDEESPLS(0.003)VS(0.498)S(0.498)PEGTGTWLHYTSGVGTGR 123.18 1.0334999999999998e-10 0.0 1636.3 3265.4 3816.8 4155.5 6828.9 4694.2 4448.4 5799.6 9728.6 3847.7 True False 1612.9660619393303 3257.839166925577 3502.9974372740676 4461.109332341629 6427.237528133961 4493.4400087146605 4678.716385811635 6069.070588480721 8632.862621300334 4512.7698182620215 0.3574226310883552 0.7219156522767765 0.7762411065369068 0.9885523773644878 1.4242334058618678 0.995716641812942 1.036772663847837 1.3448659765274864 1.912985365742643 1.0 12.139797477898737 -5.123678112582675 0.5401524370191143 1.3552443769836773 1.0086191796896127e-11 0.5889395481026494 0.2598824146633445 2.244294870235833 0.6500583386514314 0.16437214134627837 1.8300241217006985 7.5218018323867125e-06 5.123678112582675 -1.3552443769735911 TATNNASSSCQST(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 TATNNASSSCQSTPR 15 0 Q92833-2;Q92833-3;Q92833 Q92833-2 JARID2 Protein Jumonji 1 TATNNASSSCQS(0.075)T(0.925)PR;TATNNASSSCQS(0.003)T(0.997)PR;TATNNASSSCQS(0.002)T(0.998)PR 239.7 6.8004e-32 16684100.0 25121.6 28180.4 33024.5 33509.2 28482.4 35919.2 24345.699999999997 35855.5 34688.0 36341.4 True False 33109.746238259206 37289.1632022426 32586.57355217502 25784.171651979163 24528.110402011265 33673.16674578592 26512.420136129753 30314.85635242262 36521.536863044435 35069.09864746125 0.9441288061350306 1.0633054352807572 0.92921046759022 0.7352390750380963 0.6994223218733032 0.9601948166473225 0.7560051771689621 0.8644321502861664 1.041416468389567 1.0 15.097912730198662 -5.5242605031445144 24.964903975190847 0.8505628393284145 1.0018523466793068 0.1921978900742929 0.11097782133570103 59.11681776746866 1068086.5682490135 0.03020788318235258 0.05284052100932952 2.9904703227406178e-06 5.5242605031445144 0.1512895073508923 TATNNASSSCQST(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TATNNASSSCQSTPR 15 0 Q92833-2;Q92833-3;Q92833 Q92833-2 JARID2 Protein Jumonji 1 TATNNASSSCQS(0.222)T(0.778)PR;TATNNASSSCQS(0.219)T(0.781)PR;TATNNASSSCQS(0.003)T(0.997)PR 219.03 1.3441e-17 16342600.0 15242.400000000001 19523.5 17488.2 20921.2 22362.5 18654.6 24742.6 29152.5 25131.5 18705.0 True False 17822.637268877344 21461.664053683508 17905.18501236783 19749.052991445566 17980.72865554945 17676.31993645355 22398.801807088632 28387.27776462697 25499.0006433731 22096.068431301468 0.8065976680100091 0.971288811872104 0.8103335246284449 0.8937813101388163 0.8137523972399454 0.7999757962105662 1.0137007801513824 1.2847207571285997 1.1540062306854106 1.0 14.431502072276986 -7.506404517630684 4.640716244296432 1.1646956286123569 0.8555833200075754 0.7286199107326335 0.08149660200608594 0.09161270905498062 5.1301159869664446 0.03617724223784657 0.022096217332328316 3.1159858897378776e-08 7.506404517630684 -0.30911230860478145 TATNNASSSCQST(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 TATNNASSSCQSTPR 15 0 Q92833-2;Q92833-3;Q92833 Q92833-2 JARID2 Protein Jumonji 1 TATNNASSSCQS(0.031)T(0.969)PR;TATNNASSSCQS(0.051)T(0.949)PR;TATNNASSSCQS(0.003)T(0.997)PR 229.02 2.8830999999999997e-64 12837900.0 11158.7 17116.0 18680.1 16442.7 17479.7 21777.1 21391.8 21427.8 20530.5 18105.6 True False 10999.574891745044 17076.368953603906 17144.294285271262 17651.95100923924 16451.578412412433 20845.744197899545 22499.362733118724 22423.41381402978 18218.138894250606 21235.128835804473 0.5179895529147297 0.8041565975720149 0.8073553222980371 0.8312617806903225 0.7747340993134681 0.9816631845789234 1.0595350236435876 1.0559584539097189 0.8579245755991397 1.0 14.374165241246883 -4.089561373232484 0.3940939249138244 1.0079250830473887 3.0693762524923556e-15 0.7106304380469931 0.08381317436893537 5.8271507810695455 0.47025714905477345 0.07092729660270015 3.087183862818375 8.136518697391905e-05 4.089561373232484 -1.0079250830473856 TATPPGYKPGS(ph)PPSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TATPPGYKPGSPPSFR 16 1 P54259 P54259 ATN1 Atrophin-1 1 TATPPGY(0.001)KPGS(0.939)PPS(0.061)FR 60.826 0.020725 9916200.0 40153.0 48329.0 42523.0 44651.0 49069.0 45783.0 48138.0 52191.0 43887.0 36411.0 True False 46950.10984210049 53126.783724766065 43536.90958937555 42149.34923049517 39454.28169476382 43382.058883634745 43578.02015106059 50821.04155093546 44528.76434895315 43012.026070682565 1.0915577370139782 1.2351611532426234 1.0122031805204998 0.9799433572654834 0.9172848921352315 1.008603008199244 1.0131589727823542 1.181554234795175 1.035263120964776 1.0 15.392452470220096 -5.278503077754356 24.58034265856309 1.0194491612024879 1.1633594411725214 0.40445901301076537 0.07030315627118426 604.6727169903921 871033.7522789442 0.019912867923028064 0.04161688986912789 5.266194828383044e-06 5.278503077754356 0.14391027997003358 TATPPGYKPGS(ph)PPSFR ddPTM_PC-9_Lapatinib_30min_R1 1 TATPPGYKPGSPPSFR 16 1 P54259 P54259 ATN1 Atrophin-1 1 T(0.06)AT(0.07)PPGY(0.001)KPGS(0.76)PPS(0.109)FR 50.403999999999996 0.044481 55370000.0 86372.0 49221.0 72908.0 49664.0 73090.0 49832.0 52984.0 59760.0 70324.0 55700.0 True False 85140.31944131514 49107.03179862921 66913.78567301866 53316.45623424727 68790.98990046882 47700.801524065646 55727.252267296906 62536.66776460581 62403.370575450215 65327.67078441529 1.3032811122607235 0.7517033932020164 1.0242793730368505 0.816138943789904 1.0530145813323524 0.7301775947512467 0.8530420815277455 0.9572768631378281 0.9552364231901759 1.0 15.99540658185275 -4.747788844879728 24.99219782596985 0.9017667947152106 1.3032821073279846 0.5539985375197882 0.10730494898840974 497.97612626538927 911671.14594142 0.025068339936683014 0.49057746877910946 1.7873563810042263e-05 4.747788844879728 0.40151531261277396 TATPQQAQEVHEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TATPQQAQEVHEK 13 0 P60174;P60174-3;P60174-4;U3KPZ0 P60174 TPI1 Triosephosphate isomerase 0 ;; 170.26 6.579e-05 43107000.0 316528.0 317118.0 301363.0 340602.0 380927.0 387766.0 385123.0 337974.0 342758.0 309775.0 False True 370109.938687031 348599.37928014953 308548.63684554223 321519.17418658244 306287.0888573502 367430.86833697004 348641.3613909372 329102.5406130532 347770.1873155719 365934.75532244856 1.0114096387507752 0.9526271397013828 0.843179371070289 0.8786243162480462 0.8369991764992669 1.0040884693043248 0.9527418653735881 0.899347590865098 0.9503611839469287 1.0 18.48122691922049 -6.772304495128934 24.998492757965657 0.9544816573555235 0.9023860893979875 0.2042926744799275 0.055089330569819815 424.5480122561369 976795.8639712514 0.02076873067849182 0.018491161482290484 1.6892561350423348e-07 6.772304495128934 -0.052095567957536004 TATPQQAQEVHEK ddPTM_PC-9_Lapatinib_30min_R1 2 TATPQQAQEVHEK 13 0 P60174;P60174-3;P60174-4;U3KPZ0 P60174 TPI1 Triosephosphate isomerase 0 ; 210.38 2.4176e-10 90084000.0 641780.0 574150.0 680070.0 591390.0 591950.0 616630.0 574300.0 540280.0 601610.0 626290.0 False True 632628.099511961 572820.5909506722 624157.2697461171 634882.7934192087 557132.6648184772 590258.1723347369 604034.443928519 565383.3811891102 533850.3465658465 734543.3920210308 0.8612535438802887 0.7798322021175731 0.8497214412736106 0.8643230615313076 0.7584748169683704 0.8035715503623198 0.8223264282135492 0.7697072594084716 0.7267785026246097 1.0 19.486488192726164 -4.731727952028526 23.275152715901946 0.8122603302475532 0.8612542206821957 0.020752634671035164 0.07252533425409705 5612.164790864315 4395852.661189559 0.01689579625271438 1.6311266235569615 1.8546930645718914e-05 4.731727952028526 0.04899389043464253 TATVYPEPQNK ddPTM_PC-9_Lapatinib_30min_R1 2 TATVYPEPQNK 11 0 P48163;P48163-2 P48163 ME1 NADP-dependent malic enzyme 0 ; 148.56 3.2701e-07 2457200.0 52426.0 42667.0 45072.0 45760.0 41316.0 33902.0 37693.0 33060.0 38483.0 39252.0 False True 51678.39562624908 42568.20718295267 41366.354142951364 49125.3430508851 38885.87411038132 32452.090489421935 39644.55910673456 34596.08829146365 34148.639296044734 46036.65589999763 1.1225488605972298 0.9246589777376696 0.8985525411056952 1.0670919094904898 0.8446719977847765 0.7049185014636045 0.8611520174891025 0.7514900379952539 0.7417706309994269 1.0 15.490495419541928 -6.420865005498925 5.536954525502467 0.796913782067311 0.9889866074959005 0.4612796602246384 0.09767268416636797 0.20006937532061403 8.886158270571414 0.029455365789665816 0.03330379247087246 3.794329081763945e-07 6.420865005498925 0.1920728254285895 TATYNGPPAS(ph)PSLSHEATPLSQTR ddPTM_PC-9_AZD4547_30min_R2 3 TATYNGPPASPSLSHEATPLSQTR 24 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;A2SY06 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 T(0.019)AT(0.048)Y(0.109)NGPPAS(0.58)PS(0.097)LS(0.123)HEAT(0.02)PLS(0.002)QT(0.002)R;TATYNGPPAS(0.876)PS(0.123)LS(0.001)HEATPLSQTR;TATYNGPPAS(0.995)PS(0.005)LSHEATPLSQTR 148.27 1.3166999999999998e-06 42600800.0 18625.7 22298.9 55013.0 100511.6 70901.3 69973.8 42306.5 100695.3 57199.8 75567.1 True False 24548.28516137288 29506.583346243748 54283.49167514433 77340.20350874001 61057.87834052335 65598.32722433339 46071.69654144975 85135.15513279955 60223.26465229387 72921.51882983503 0.3366397951564501 0.40463478846482087 0.7444097784333977 1.0605950719322803 0.8373094707887817 0.8995743407019461 0.6317983673510655 1.1674901524125614 0.8258641018274319 1.0 16.15405699009615 -5.337483339852901 2.940974075196459 0.9087385305628182 0.35013698807174315 0.7092337398333369 0.138161462304666 0.1351105474266247 2.2512577111042393 0.0366153381922985 0.09703138651575115 4.597446246429633e-06 5.337483339852901 -0.5586015424910751 down TATYNGPPAS(ph)PSLSHEATPLSQTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TATYNGPPASPSLSHEATPLSQTR 24 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;A2SY06 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 TATYNGPPAS(0.996)PS(0.003)LSHEATPLSQTR 118.98 7.2311e-09 6762200.0 2898.5 5841.7 9461.3 10450.0 13782.0 13187.0 12889.0 15683.0 16992.0 7816.0 True False 3389.158802015497 6421.625369549664 9686.893274180056 9864.520379357109 11081.516034914815 12495.45050561325 11668.060611720886 15271.337867512053 17240.47585429424 9232.978928578039 0.3670709993202007 0.695509587883209 1.0491622854458225 1.0684006164927242 1.2002102594012383 1.3533498345736679 1.263737381183201 1.6539989948687097 1.867271222826177 1.0 13.172580478807182 -5.159386406936955 0.5664232510900549 1.4964957539699666 1.0614189938460274e-14 0.7049762330239401 0.22290336519082474 1.4986044253114532 0.49331347736262304 0.13143628900486767 1.3945363389601722 6.92809115295379e-06 5.159386406936955 -1.496495753969956 TATYNGPPAS(ph)PSLSHEATPLSQTR ddPTM_PC-9_Lapatinib_30min_R1 3 TATYNGPPASPSLSHEATPLSQTR 24 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;A2SY06 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 TATYNGPPAS(0.967)PS(0.03)LS(0.001)HEATPLSQTR;TATYNGPPAS(0.948)PS(0.052)LSHEATPLSQTR;TATYNGPPAS(0.999)PS(0.001)LSHEATPLSQTR 167.26 2.9854000000000004e-10 29179000.0 37301.7 34604.8 60987.0 35875.9 48675.0 54258.5 34106.3 43429.0 63301.0 35905.6 True False 36769.77091770599 34524.67471171258 55972.884276627985 38514.33336449404 45812.032198732 51937.990437741166 35872.157330592454 45446.86988535923 56171.37479091881 42111.83511879534 0.8731457751480157 0.8198330615210719 1.329148542653896 0.9145726671812585 1.0878659661707593 1.2333347689842238 0.8518307793853896 1.079194714672394 1.3338619566794518 1.0 15.36193812513717 -5.21947333722816 24.992159962142438 1.0948653190640407 0.8464892098885793 0.31072017480548275 0.15279666051493954 593.4888414352281 353440.30909846467 0.03774403327122022 0.09985927673362242 6.032907447999654e-06 5.21947333722816 -0.24837610917546138 TATYNGPPASPS(ph)LSHEATPLSQTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TATYNGPPASPSLSHEATPLSQTR 24 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;A2SY06 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 TATYNGPPAS(0.449)PS(0.551)LSHEATPLSQTR 149.97 1.018e-06 11211000.0 1868.4 6716.3 14335.0 15163.0 18209.0 17701.0 13564.0 13950.0 13960.0 8862.7 True False 2184.6832174178885 7383.049877519635 14676.80076579024 14313.466269109274 14641.077164400207 16772.728399170413 12279.119725144083 13583.827281246768 14164.1385902747 10469.437352905408 0.2086724571508716 0.7052002537147557 1.401871014751068 1.3671667145643789 1.3984588350716969 1.6020658831790764 1.1728538326595424 1.2974744318496805 1.3529035145660395 1.0 13.353896290778568 -5.0261505949457055 2.5314145910374335 1.3454841386487786 0.18990161475774306 0.8471285888716372 0.1537619367262293 0.11247484826247997 1.2678506338485018 0.04021018235426765 0.2217610475902885 9.41563045694578e-06 5.0261505949457055 -1.1555825238910356 down TAVAPSAVNLADPRT(ph)PTAPAVNLAGAR ddPTM_PC-9_AZD4547_30min_R2 3 TAVAPSAVNLADPRTPTAPAVNLAGAR 27 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 TAVAPSAVNLADPRT(0.929)PT(0.071)APAVNLAGAR;TAVAPSAVNLADPRT(0.912)PT(0.088)APAVNLAGAR;TAVAPS(0.01)AVNLADPRT(0.617)PT(0.373)APAVNLAGAR 101.3 1.026e-09 96521000.0 62795.1 57884.9 95221.6 161041.0 126724.0 105210.0 66383.3 98828.0 98162.0 106552.0 True False 82762.63558077955 76595.06192408527 93958.89936731184 123915.48550864783 109130.56001546505 98631.20206808971 72291.28509850784 83556.40344151454 103350.6429183053 102821.64691190493 0.8049145103821236 0.7449312885418966 0.9138046529036199 1.2051497834382636 1.0613578297278727 0.9592454996620946 0.7030745691171942 0.8126343620337421 1.0051447921939394 1.0 16.649784499715977 -5.355969207292792 5.25297225704468 0.9562420415058009 0.7761356036850446 0.24888433843641944 0.12825179606603263 0.3417146201782323 14.615318295407418 0.0386816654667698 0.08335290107229501 4.405861011999326e-06 5.355969207292792 -0.1801064378207563 TAVAPSAVNLADPRT(ph)PTAPAVNLAGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TAVAPSAVNLADPRTPTAPAVNLAGAR 27 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 TAVAPS(0.001)AVNLADPRT(0.721)PT(0.278)APAVNLAGAR;TAVAPSAVNLADPRT(0.967)PT(0.033)APAVNLAGAR;T(0.001)AVAPS(0.125)AVNLADPRT(0.471)PT(0.403)APAVNLAGAR;TAVAPSAVNLADPRT(0.73)PT(0.27)APAVNLAGAR 96.045 2.0540999999999998e-09 68337000.0 54792.4 40668.7 39553.4 51686.0 66665.0 62683.0 68299.0 66617.0 53807.1 46271.0 True False 64067.671120770705 44706.0197659251 40496.50306310482 48790.20098827292 53602.47180870676 59395.79313288509 61829.22427806077 64868.37433654598 54593.92704446775 54659.56601896555 1.1721218404577303 0.817899281352018 0.7408859237750537 0.8926196188850805 0.9806603987691377 1.086649555766253 1.1311693227971755 1.186770753248173 0.9987991310711282 1.0 15.738186384877606 -6.568205256194317 2.6470759994601374 1.096626116947833 0.8890130525068725 0.3270004721406715 0.11642943729932004 0.2949890603153961 4.194867028799191 0.042070659019318765 0.04371716422420466 2.7026807216469035e-07 6.568205256194317 -0.20761306444096062 TAVAPSAVNLADPRT(ph)PTAPAVNLAGAR ddPTM_PC-9_Lapatinib_30min_R1 4 TAVAPSAVNLADPRTPTAPAVNLAGAR 27 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 TAVAPSAVNLADPRT(0.683)PT(0.317)APAVNLAGAR;TAVAPSAVNLADPRT(0.752)PT(0.248)APAVNLAGAR;TAVAPS(0.012)AVNLADPRT(0.929)PT(0.059)APAVNLAGAR;TAVAPS(0.002)AVNLADPRT(0.755)PT(0.243)APAVNLAGAR 108.94 2.628e-10 80790000.0 95155.0 52427.8 76621.0 62751.0 78892.0 96619.0 79515.0 63860.0 93456.0 78046.0 True False 93798.07225070997 52306.40665025443 70321.51714561321 67365.9178711995 74251.7276676397 92486.83059988971 83631.89763011684 66827.16873239157 82930.00114469134 91536.14711024192 1.0247107313545096 0.5714289742527507 0.768237678399564 0.7359488027179809 0.811173836912912 1.010385880547308 0.9136488728261027 0.7300631591136123 0.9059809022201281 1.0 16.482053947630376 -6.532817285799063 24.088131954538433 0.8969727099717154 0.7617354737622412 0.2073146888299814 0.12560851515122082 216.01415919404184 523549.6319833799 0.04051664687831191 0.040570047379138774 2.932126575410438e-07 6.532817285799063 -0.13523723620947425 TAVETAVLLLR ddPTM_PC-9_Lapatinib_30min_R1 2 TAVETAVLLLR 11 0 P49368-2;P49368;B4DUR8 P49368-2 CCT3 T-complex protein 1 subunit gamma 0 ; 112.71 0.0076194 5321800.0 17136.4 13635.599999999999 16850.6 16175.0 12733.0 10216.3 13473.6 12465.5 12244.6 16897.2 False True 16892.031793569113 13604.027605968768 15465.208713197024 17364.563458218236 11984.06997404118 9779.372664358485 14171.197081168875 13044.69263754507 10865.484206645779 19817.858505896253 0.8523641335184303 0.6864529586746856 0.7803672989488638 0.8762078633799859 0.6047106437093419 0.4934626342926459 0.7150720688086772 0.6582291741392736 0.5482673217902457 1.0 14.274513454594404 -4.759665294077187 24.183088515649388 0.694261226068927 0.8523644217991826 0.07878415272057437 0.1433321340924749 77.79610124745018 1059982.5386292243 0.03549559373573207 0.22102060763149642 1.7391406487294562e-05 4.759665294077187 0.15810319573025555 TAVIPINGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 TAVIPINGSPR 11 0 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 TAVIPINGS(1)PR;TAVIPINGS(1)PR;TAVIPINGS(1)PR;TAVIPINGS(1)PR 120.9 0.00082131 260053000.0 322924.0 271711.0 461073.0 496463.0 453457.0 409633.0 389285.0 458086.0 333485.0 388045.0 True False 425607.1147635341 359536.2671517982 454958.8707602541 382011.1256268887 390502.3227875754 384018.5837539961 423930.61085502885 387299.33446907427 351112.33627687884 374459.6626617065 1.1365900181030584 0.9601468542597327 1.2149743113219433 1.0201662921755188 1.0428421582496648 1.025527238432956 1.132112889921645 1.0342885311493948 0.93765062378449 1.0 18.514450792287185 -8.04247229156268 6.084945830829443 0.9726827848994952 1.0724205727921312 0.2713600090119944 0.06957688080183007 0.27880359496065793 27.083027401473146 0.04414827793623725 0.01694438543137119 9.068338196742956e-09 8.04247229156268 0.09973778789263599 TAVIPINGS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 TAVIPINGSPR 11 0 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 TAVIPINGS(1)PR;TAVIPINGS(1)PR;TAVIPINGS(1)PR;TAVIPINGS(1)PR;TAVIPINGS(1)PR;TAVIPINGS(1)PR 99.834 0.0043978 234765000.0 312553.0 350773.0 356325.0 380248.0 409438.0 336605.0 376954.0 337261.0 312180.0 247708.0 True False 365462.0496968603 385595.4252620033 364821.1393700875 358943.93734064966 329211.56307527516 318952.8412407638 341246.1882093753 328408.2561075682 316745.04191346455 292615.4995445503 1.248949731868934 1.3177546160821085 1.2467594503296089 1.226674382933707 1.1250653625241513 1.090006652884782 1.1661931399413825 1.1223200979398855 1.0824616003132825 1.0 18.15864666402198 -4.170946259829573 0.16793270676312927 0.9709043758739573 1.67764104491136 0.8339327779757645 0.03732532219187367 10.219804844553684 0.2463131327046198 0.13122491148723484 1.5818486994802259 6.746114998476602e-05 4.170946259829573 0.7067366690374026 TAVIPINGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 6 TAVIPINGSPR 11 0 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 TAVIPINGS(1)PR;TAVIPINGS(1)PR;TAVIPINGS(1)PR;TAVIPINGS(1)PR;TAVIPINGS(1)PR;TAVIPINGS(1)PR 139.19 0.00010879 283822100.0 778055.0 749114.0 712005.0 637890.0 674599.0 680737.0 551161.0 606226.0 661415.0 501758.0 True False 766959.7930221861 747379.4725584261 653466.6973187806 684802.5585386606 634920.413132663 651623.4653854523 579697.419728515 634393.4730968188 586919.477691278 588486.2017494899 1.3032757450253183 1.2700033923252032 1.1104197437019125 1.1636679951081865 1.0789045031899311 1.1072875854153654 0.9850654407956431 1.0780090870624541 0.9973377046844017 1.0 19.16664906319083 -1.5228787454989101 0.2820807245752654 0.9952728089213188 3.5496127477299533 0.8655347414029445 0.03814907073141673 16.451942117861975 0.23226594423362756 0.0395630735776261 20.763993474591544 0.02999999998490154 1.5228787454989101 2.5543399388086345 TAVPS(ph)PVEAAAASDPAAAR ddPTM_PC-9_AZD4547_30min_R2 4 TAVPSPVEAAAASDPAAAR 19 0 Q147X3;Q147X3-2;J3KNC2 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 T(0.151)AVPS(0.849)PVEAAAASDPAAAR;T(0.001)AVPS(0.999)PVEAAAASDPAAAR;T(0.009)AVPS(0.991)PVEAAAASDPAAAR;T(0.002)AVPS(0.997)PVEAAAAS(0.001)DPAAAR 184.2 8.576299999999998e-11 36300700.0 102141.0 99157.0 139089.0 191098.0 162442.0 140617.0 111417.0 154293.0 103793.0 138034.0 True False 134619.71333521884 131207.56112918083 137244.58898086185 147043.30853466838 139889.7322530237 131824.1967608461 121332.89715667132 130450.5621504185 109279.2860823909 133201.47167427948 1.0106473422786755 0.9850308670014216 1.0303533981701725 1.103916546014121 1.050211611738789 0.9896602124877324 0.9108975721632366 0.9793477542756596 0.8204059963362414 1.0 17.023250496526586 -7.047906656588442 3.3866641524382812 0.9262426339031608 1.0362404306191435 0.4816530143583089 0.05284578235590491 0.21889820583048147 5.0518461651921704 0.021121596838106507 0.016654754773026643 8.955572280088652e-08 7.047906656588442 0.10999779671598275 TAVPS(ph)PVEAAAASDPAAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TAVPSPVEAAAASDPAAAR 19 0 Q147X3;Q147X3-2;J3KNC2 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 T(0.051)AVPS(0.949)PVEAAAAS(0.001)DPAAAR;TAVPS(1)PVEAAAASDPAAAR;T(0.029)AVPS(0.971)PVEAAAASDPAAAR 152.13 4.9072e-05 30192400.0 63932.0 58875.0 75272.0 78018.0 89947.0 75656.0 71085.0 65926.0 64474.0 57667.0 True False 74754.42488544225 64719.72090868015 77066.76995064948 73646.9043977686 72322.53103994225 71688.46617522372 64351.31418916749 64195.51235437099 65416.81027717557 68121.57060827925 1.0973679000342496 0.9500620777057415 1.1313122886406712 1.081109900141055 1.0616685786036828 1.0523607358887137 0.9446540004077133 0.9423668858652079 0.9602950973245038 1.0 16.055824077670046 -7.228151469747854 6.296304375178261 0.9569457394050026 1.061576786281113 0.5318645072425487 0.04610597737706194 0.1522981929980734 19.60916929876933 0.01785400748407494 0.013499669668696573 5.913553500261472e-08 7.228151469747854 0.10463104687611036 TAVPS(ph)PVEAAAASDPAAAR ddPTM_PC-9_Lapatinib_30min_R1 4 TAVPSPVEAAAASDPAAAR 19 0 Q147X3;Q147X3-2;J3KNC2 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 T(0.008)AVPS(0.992)PVEAAAASDPAAAR;TAVPS(1)PVEAAAASDPAAAR;T(0.062)AVPS(0.938)PVEAAAASDPAAAR;T(0.1)AVPS(0.9)PVEAAAASDPAAAR 184.21 8.5664e-11 30516200.0 150487.0 132383.0 143404.0 125406.0 144232.0 141381.0 123067.0 120886.0 146551.0 106621.0 True False 148341.02778406406 132076.47529708705 131613.8766754484 134628.7755821522 135748.55733102217 135334.4642052079 129438.80708854446 126502.80487603966 130044.88312955471 125050.29778644793 1.1862508959186198 1.056186811507142 1.052487511067021 1.0765970010888075 1.0855516518868589 1.0822402393341162 1.0350939532314503 1.011615382892348 1.039940611350132 1.0 16.93214896749764 -1.5228787452803376 0.20565691595476593 1.0066400032216574 1.6213572584475264 0.5944047428172496 0.03141331949394564 42.85695209899837 0.5268295211127088 0.058293710801943274 8.5610442033327 0.029999999999999995 1.5228787452803376 0.6147172552258691 TAVSVTQGGHS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 TAVSVTQGGHSR 12 0 P40425 P40425 PBX2 Pre-B-cell leukemia transcription factor 2 1 TAVSVTQGGHS(1)R 90.49799999999999 0.0039192 8002700.0 9506.5 10389.0 20570.0 28342.0 20154.0 16921.0 15508.0 19814.0 16848.0 19548.0 True False 12529.369252516215 13747.041082032132 20297.228359800753 21808.189779534976 17355.964983362894 15862.927195077942 16888.18195702322 16752.20158042424 17738.550884126296 18863.630469948126 0.6642077341621435 0.7287590320396017 1.0759979841704654 1.1560971687967416 0.9200755395952486 0.840926523680018 0.8952773955113243 0.8880687949815583 0.940357208141126 1.0 14.20331974150844 -5.131922940630378 5.594723268454561 0.9583802954567667 0.6807090315548967 0.5922717949959839 0.08938675668526025 0.16913018326985213 6.8448072369961634 0.026124345943812095 0.07285769829956422 7.380351723404286e-06 5.131922940630378 -0.27767126390187 TAVSVTQGGHS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TAVSVTQGGHSR 12 0 P40425 P40425 PBX2 Pre-B-cell leukemia transcription factor 2 1 TAVSVTQGGHS(1)R;TAVSVTQGGHS(1)R;TAVSVTQGGHS(1)R;TAVSVTQGGHS(1)R 130.47 8.214600000000001e-05 20751100.0 69772.1 118428.0 144886.0 136583.0 190125.0 124357.0 96327.0 84475.0 100787.0 95423.0 True False 81583.13846820964 130184.74917661404 148340.6317232149 128930.69731806072 152871.37107373198 117835.5000020131 87202.20921291318 82257.62075866082 102260.81920472917 112722.43453194744 0.7237524527123977 1.1549142787518265 1.3159814400670407 1.1437891476831046 1.3561752077879905 1.0453597856655281 0.7736011875098262 0.7297360201650686 0.9071913646058338 1.0 16.78241515025696 -7.097312302567218 4.6425240513546955 0.8329924559137638 1.154254122876597 0.3728607614502062 0.17357288522661488 0.2275216355818987 8.117749804467211 0.068947397270906 0.05336210003652257 7.99259298357535e-08 7.097312302567218 0.3212616669628332 TAVSVTQGGHS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 2 TAVSVTQGGHSR 12 0 P40425 P40425 PBX2 Pre-B-cell leukemia transcription factor 2 1 TAVSVTQGGHS(1)R;TAVSVTQGGHS(1)R 121.13 0.00026136 12413200.0 87454.0 60390.0 109004.0 69058.0 72359.0 74993.0 56544.0 60059.0 71576.0 41031.0 True False 86206.8899229006 60250.17066535056 100042.11188760813 74136.7556907348 68102.98588326754 71785.7242072214 59471.57164808312 62849.560396158944 63514.35715130572 48123.15367962912 1.7913807248961036 1.2519996313303734 2.0788768864488754 1.5405631182088848 1.4151812729616686 1.4917086416472498 1.2358203297315875 1.306014996742901 1.3198294852856205 1.0 15.55444357004507 -7.464303895266148 0.4012356519388909 1.0217907854564001 1.7211782388780263 0.4952529507605772 0.20688322741369336 1.0285641497090086 0.41566535918502245 0.23412962811280671 0.2410191481547924 3.433176291340674e-08 7.464303895266148 0.6993874534216262 TAVVVGTITDDVR ddPTM_PC-9_Lapatinib_30min_R1 2 TAVVVGTITDDVR 13 0 F8VUA6;G3V203;H0YHA7;J3QQ67;Q07020-2;Q07020;F8VYV2;A0A075B7A0 F8VUA6 RPL18 60S ribosomal protein L18 0 ; 193.3 6.7328e-06 19872500.0 125725.0 131323.0 123577.0 121390.0 124925.0 121252.0 106525.0 105753.0 129122.0 115529.0 False True 123932.1384448586 131018.92966196137 113416.97608101495 130317.42554516885 117577.15711199968 116066.33461221722 112040.34326917189 110666.67045030725 114578.920645061 135498.03371728375 0.9146416006555685 0.9669434018159406 0.8370378002507338 0.9617661745341323 0.8677406888230134 0.8565905454715992 0.8268780010708033 0.8167400471745069 0.8456131613254964 1.0 17.047912390466834 -6.4434145342613895 7.715392297402854 0.8558160397986941 0.917459843709406 0.1357802775589867 0.05843583404404725 0.47410684359158517 41.282325348756025 0.01727154549471237 0.019546740354016188 3.6023463476287876e-07 6.4434145342613895 0.06164380391071189 TAWVFDDK ddPTM_PC-9_Lapatinib_30min_R1 1 TAWVFDDK 8 0 P05198;H0YJS4;G3V4T5 P05198 EIF2S1 Eukaryotic translation initiation factor 2 subunit 1 0 97.635 0.022936 0.0 20014.0 17857.0 15480.0 20526.0 19656.0 22421.0 23628.0 21908.0 19220.0 17180.0 False True 19728.59668988191 17815.653213630812 14207.29415452802 22035.550512728732 18499.872725182857 21462.10609590375 24851.342227308105 22925.92565908609 17055.24120442741 20149.540109088954 0.9791090309293379 0.884171704027856 0.7050927255714121 1.0936006674806957 0.918128782345659 1.0651412379492835 1.2333453812227846 1.1377890281845577 0.8464332740147363 1.0 14.29845929076382 -5.784475655124867 24.999915154071033 1.051571681697228 0.8589291188504062 0.33360084697870074 0.11988336325433571 258.3775324065023 280400.98560339445 0.03510499718524265 0.0521071617251095 1.642571733335808e-06 5.784475655124867 -0.1926425628468218 TCDSIT(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TCDSITPSK 9 0 Q76FK4-2;Q76FK4-4;Q76FK4;F8WE42;F5H101;F5GWN9 Q76FK4-2 NOL8 Nucleolar protein 8 1 TCDS(0.001)IT(0.767)PS(0.232)K 85.92399999999999 0.029488 3260000.0 29733.0 23812.0 35391.0 40990.0 46972.0 48249.0 51866.0 51266.0 38785.0 39054.0 True False 34766.20964648154 26175.89799197438 36234.855661114925 38693.46319137301 37768.17379132337 45718.73750248985 46952.87700267791 49920.32182081695 39352.15725098886 46134.18104870608 0.7535889628077971 0.5673862068633931 0.785423190299185 0.838715726860361 0.8186592442477668 0.9909948862909775 1.017745973492138 1.0820680173798611 0.8529935149264466 1.0 15.493548426448848 -6.131350521187367 0.9488421021049576 0.9999360548010929 0.6594963095673162 0.7074696181549784 0.07921707259838459 0.30592338035588124 0.573687579911788 0.03573181973516934 0.06656836752471278 7.3900857687705e-07 6.131350521187367 -0.34043974523377674 TCDSITPSKS(ph)SPVPVSDTQK ddPTM_PC-9_Lapatinib_30min_R1 1 TCDSITPSKSSPVPVSDTQK 20 1 Q76FK4-2;Q76FK4-4;Q76FK4;F8WE42;F5H101;F5GWN9 Q76FK4-2 NOL8 Nucleolar protein 8 1 TCDSIT(0.001)PS(0.004)KS(0.479)S(0.479)PVPVS(0.022)DT(0.016)QK 62.556000000000004 0.0046225 61696000.0 37092.0 29746.0 34380.0 27079.0 33081.0 30232.0 26760.0 27525.0 33776.0 22581.0 True False 36563.06127816026 29677.124964588806 31553.40911063783 29070.479992895915 31135.240619748365 28939.047834234072 28145.50186231438 28803.911984952712 29971.791202952143 26484.095762708814 1.3805667222228986 1.1205640256888048 1.191409719755919 1.097658015337223 1.175620300527256 1.092695332833752 1.0627322191586743 1.0875928044902456 1.1316901838557092 1.0 14.692838631589478 -1.6296355024097615 0.9933243767086457 1.1002244548454083 199.99999983084305 0.7113909125023956 0.052147952118160236 671.7978201418798 1.2073127259949197 0.01632047960640961 303700.23918057245 0.023461971212988982 1.6296355024097615 198.89977537599765 TCDSITPSKSS(ph)PVPVSDTQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TCDSITPSKSSPVPVSDTQK 20 1 Q76FK4-2;Q76FK4-4;Q76FK4;F8WE42;F5H101;F5GWN9 Q76FK4-2 NOL8 Nucleolar protein 8 1 TCDSIT(0.007)PS(0.059)KS(0.175)S(0.666)PVPVS(0.059)DT(0.034)QK 58.29 0.00824 30933000.0 108520.0 87093.0 101030.0 123000.0 134030.0 136890.0 120530.0 132370.0 130880.0 82084.0 True False 126890.29263229998 95739.0174624148 103438.93835840862 116108.70877138065 107767.78364240564 129711.24741892757 109112.5258383676 128895.42775760846 132793.87239936605 96965.17942341341 1.3086171075723374 0.9873546156642027 1.0667637493530182 1.1974268439639972 1.1114070461502576 1.3377095591451793 1.1252753461313254 1.329296026924951 1.3695006103118845 1.0 16.565179142396012 -6.735081975716154 24.961110552816383 1.2462447784902597 1.1259029122474498 0.11963990463898555 0.12927829853403258 389.4445351160152 368812.53353535867 0.04113541292115186 0.04112345336955826 1.8404245773851436e-07 6.735081975716154 -0.12034186624280996 TCDSITPSKSSPVPVS(ph)DTQK ddPTM_PC-9_AZD4547_30min_R2 2 TCDSITPSKSSPVPVSDTQK 20 1 Q76FK4-2;Q76FK4-4;Q76FK4;F8WE42;F5H101;F5GWN9 Q76FK4-2 NOL8 Nucleolar protein 8 1 TCDSITPS(0.003)KS(0.025)S(0.394)PVPVS(0.497)DT(0.08)QK;TCDSITPSKSSPVPVS(0.603)DT(0.397)QK 130.64 1.7217e-05 96414000.0 193810.0 183869.0 209961.0 269737.0 255367.0 224453.0 199445.0 218422.0 178776.0 217137.0 True False 255437.54850156963 243301.05849573272 207176.77995391987 207553.30204510712 219913.7000052805 210417.91842780152 217195.2186238392 184669.89873823652 188225.7343815623 209535.09972135938 1.2190680646882146 1.1611470289191426 0.9887449894047555 0.9905419298299537 1.049531559618043 1.0042132258872911 1.036557688485921 0.8813315715782764 0.8983016908950607 1.0 17.676832407871906 -1.522878745280387 0.4515199815251158 0.9543846340032166 7.449370328902977 0.7140621732518619 0.05270388481035952 50.24222445824007 0.6031534053959245 0.03550292910912293 301.1358838117853 0.029999999999996592 1.522878745280387 6.494985694899761 TCDSITPSKSSPVPVS(ph)DTQK ddPTM_PC-9_Lapatinib_30min_R1 1 TCDSITPSKSSPVPVSDTQK 20 1 Q76FK4-2;Q76FK4-4;Q76FK4;F8WE42;F5H101;F5GWN9 Q76FK4-2 NOL8 Nucleolar protein 8 1 TCDSITPS(0.001)KS(0.027)S(0.291)PVPVS(0.43)DT(0.251)QK 72.676 0.0015037000000000002 54405000.0 122560.0 84577.0 91783.0 79761.0 95645.0 100640.0 92416.0 76729.0 93605.0 70553.0 True False 120812.27192524874 84381.16715289543 84236.95603262575 85626.89001489618 90019.34914530498 96335.86180329835 97200.84828503909 80294.1094529861 83062.21919565187 82747.99204403683 1.4600024597691128 1.0197367340102883 1.0179939591500482 1.034791152023692 1.0878735171893776 1.1642078487177105 1.174661111212351 0.970345110129744 1.0037973991132958 1.0 16.336436683574952 -4.758079134977624 24.992058809019888 1.058440396845001 1.4600030205485026 0.7744500659016381 0.06589039095045252 48.92242024171374 363805.31267057115 0.0180208672157885 0.12713707064085303 1.7455040668832286e-05 4.758079134977624 0.4015626237035017 TCEERPAEDGS(ph)DEEDPDSMEAPTR ddPTM_PC-9_Lapatinib_30min_R1 1 TCEERPAEDGSDEEDPDSMEAPTR 24 1 D6RGJ8;Q9H6Y2 D6RGJ8 WDR55 WD repeat-containing protein 55 1 TCEERPAEDGS(0.999)DEEDPDSMEAPTR 105.58 7.0336e-07 49889000.0 29926.0 27110.0 26696.0 26883.0 23618.0 24290.0 27161.0 22066.0 29595.0 21885.0 True False 29499.24975224373 27047.228460633425 24501.15792954006 28860.06549905909 22228.835674774567 23251.173322755563 28567.263680206324 23091.26691589344 26261.699450833963 25667.793090070518 1.1492709812927155 1.053741876667088 0.9545486767624846 1.124368791574196 0.8660205260643815 0.9058501150124272 1.112961429132661 0.8996202686714895 1.0231381934036703 1.0 14.647671638264402 -3.474061024371343 0.8442483553967877 0.978553751845149 2.4824474317600065 0.27728345836930746 0.08158055703669125 23.270532197820916 2.2677640591039223 0.02786814639885996 53.56733464540807 0.0003356904417866362 3.474061024371343 1.5038936799148575 TCFS(ph)PNRVIGLSSDLQQVGGASAR ddPTM_PC-9_AZD4547_30min_R2 1 TCFSPNRVIGLSSDLQQVGGASAR 24 1 O00303 O00303 EIF3F Eukaryotic translation initiation factor 3 subunit F 1 T(0.107)CFS(0.888)PNRVIGLS(0.002)S(0.003)DLQQVGGASAR 54.261 0.004084900000000001 7967400.0 6410.0 5767.5 9661.9 23616.0 15167.0 8314.2 7843.6 7656.3 7690.8 10931.0 True False 8448.246663717342 7631.731585390347 9533.776893026688 18171.696063562846 13061.323851476865 7794.3117596665115 8541.665204933408 6473.194759271326 8097.319986920613 10548.309017137452 0.8009100463393503 0.723502845147156 0.903820401690689 1.7227117667902938 1.2382386437728181 0.7389157586304477 0.8097663038744957 0.6136713238827725 0.7676415218557964 1.0 13.364724120840052 -6.776482512055317 24.70081827575702 0.7633387947899737 1.0843103372324814 0.2176213588409841 0.27486436428434696 345.53385971177966 567362.5353431747 0.10810417979414615 0.09572636902775203 1.6730830058799424e-07 6.776482512055317 0.3209715424425077 TCFS(ph)PNRVIGLSSDLQQVGGASAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TCFSPNRVIGLSSDLQQVGGASAR 24 1 O00303 O00303 EIF3F Eukaryotic translation initiation factor 3 subunit F 1 T(0.117)CFS(0.883)PNRVIGLSSDLQQVGGASAR 78.352 8.9141e-05 8852500.0 8799.0 2686.1 8659.6 14137.0 13544.0 14886.0 13979.0 16642.0 16318.0 12318.0 True False 10288.496911828306 2952.7582561835343 8866.07770571588 13344.949722772393 10890.150426417516 14105.351954694694 12654.807920804284 16205.165133656543 16556.619879376965 14551.155890765654 0.7070570193229471 0.20292259105391014 0.609304014902514 0.9171058177750171 0.7484044915860287 0.9693629881077782 0.8696771593819006 1.1136685810603226 1.1378216276195627 1.0 13.828846139668556 -6.0132992925465745 0.721314200900925 1.055197171032365 0.3969630442400661 0.6516314379577374 0.15575192196377077 0.5260853345919011 0.5394606309717662 0.08671610957756141 0.21798335106228844 9.698413740496276e-07 6.0132992925465745 -0.658234126792299 TCFS(ph)PNRVIGLSSDLQQVGGASAR ddPTM_PC-9_Lapatinib_30min_R1 2 TCFSPNRVIGLSSDLQQVGGASAR 24 1 O00303 O00303 EIF3F Eukaryotic translation initiation factor 3 subunit F 1 T(0.255)CFS(0.745)PNRVIGLSSDLQQVGGASAR;T(0.02)CFS(0.98)PNRVIGLSSDLQQVGGASAR 88.684 7.500399999999999e-06 11419300.0 49259.0 24728.1 31652.1 31156.0 25158.8 25913.0 16122.2 18322.9 34141.0 18719.4 True False 48556.55762700574 24670.843603739933 29049.786518639306 33447.31617336921 23679.008848103906 24804.76139615334 16956.92862946955 19174.248825035065 30295.681059331724 21955.02334796738 2.211637713038513 1.1236992652082052 1.3231498804727424 1.5234470782954461 1.078523510215084 1.1297989076586334 0.7723484671693341 0.8733422197344298 1.379897464884114 1.0 14.422263448242045 -2.7342845145531216 1.2660438541114136 1.106205676864441 199.99999998605134 0.6664881561038578 0.2246607313290777 176.43085637787064 2.0299475854535087 0.07000384791483394 100168.54419622291 0.0018438071104169293 2.7342845145531216 198.8937943091869 TCNS(ph)PQNSTDSVSDIVPDSPFPGALGSDTR ddPTM_PC-9_AZD4547_30min_R2 3 TCNSPQNSTDSVSDIVPDSPFPGALGSDTR 30 0 Q14694;Q14694-3;Q14694-2 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 T(0.289)CNS(0.625)PQNS(0.084)T(0.001)DSVSDIVPDSPFPGALGSDTR;T(0.042)CNS(0.958)PQNSTDSVSDIVPDSPFPGALGSDTR;T(0.285)CNS(0.714)PQNSTDSVSDIVPDSPFPGALGSDTR 148.02 1.0014000000000001e-16 19384200.0 27109.2 27102.3 33797.4 47359.0 39615.1 30918.5 23100.6 37934.0 26176.3 37611.8 True False 35729.36169361093 35862.58846063718 33349.22439317113 36441.11423925615 34115.22717140115 28985.161307311453 25156.508648208055 32072.17193660107 27559.925778024397 36295.02233014096 0.9844149252372749 0.9880855874513496 0.9188374121890672 1.004025122447545 0.9399423111270658 0.7985988007848922 0.6931118107431774 0.8836520789234217 0.7593307293583738 1.0 15.147484083361821 -6.690195419704711 4.724027834758059 0.8112169254029173 0.970564241674848 0.4379475575590409 0.07888144214971611 0.17562383543262225 7.39252290420638 0.025443825761612204 0.025026398461808277 2.0408194294957146e-07 6.690195419704711 0.15934731627193066 TCNS(ph)PQNSTDSVSDIVPDSPFPGALGSDTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TCNSPQNSTDSVSDIVPDSPFPGALGSDTR 30 0 Q14694;Q14694-3;Q14694-2 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 T(0.069)CNS(0.93)PQNSTDSVSDIVPDSPFPGALGSDTR;T(0.096)CNS(0.848)PQNS(0.032)T(0.013)DS(0.005)VS(0.005)DIVPDSPFPGALGSDTR;T(0.136)CNS(0.857)PQNS(0.006)T(0.001)DSVSDIVPDSPFPGALGSDTR;T(0.079)CNS(0.904)PQNS(0.009)T(0.007)DS(0.001)VSDIVPDSPFPGALGSDTR 150.45 9.531600000000001e-17 30098400.0 44467.8 51265.7 52770.8 59465.5 58123.3 52571.0 50982.9 53267.5 46235.3 38177.4 True False 51995.32026091591 56355.01989279185 54029.056006373445 56133.8408247522 46734.456606600215 49814.0842140437 46153.43062776826 51869.2845665815 46911.403793905985 45098.66040786787 1.1529238294591309 1.2495940984304759 1.1980190878784414 1.244689760562359 1.036271503054378 1.1045579572326538 1.0233880609836556 1.1501291634270456 1.0401950605548778 1.0 15.460796960444108 -6.261625897014529 24.99999544372576 1.067085018350683 1.2130923973212657 0.7099083561431503 0.04749858058267098 9.107192136093808 1220687.502714367 0.01348351300127452 0.016299268905632523 5.474873676150706e-07 6.261625897014529 0.1460073789705827 TCNS(ph)PQNSTDSVSDIVPDSPFPGALGSDTR ddPTM_PC-9_Lapatinib_30min_R1 7 TCNSPQNSTDSVSDIVPDSPFPGALGSDTR 30 0 Q14694;Q14694-3;Q14694-2 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 T(0.09)CNS(0.908)PQNS(0.001)TDSVSDIVPDSPFPGALGSDTR;T(0.059)CNS(0.933)PQNS(0.005)T(0.003)DS(0.001)VSDIVPDSPFPGALGSDTR;T(0.058)CNS(0.827)PQNS(0.108)T(0.006)DS(0.001)VSDIVPDSPFPGALGSDTR;T(0.039)CNS(0.961)PQNS(0.001)TDSVSDIVPDSPFPGALGSDTR;T(0.078)CNS(0.912)PQNS(0.01)TDSVSDIVPDSPFPGALGSDTR;T(0.183)CNS(0.816)PQNS(0.001)TDSVSDIVPDSPFPGALGSDTR;T(0.155)CNS(0.785)PQNS(0.038)T(0.015)DS(0.006)VS(0.001)DIVPDSPFPGALGSDTR 200.33 2.422e-77 24744300.0 61182.7 60844.0 64175.8 43866.37 57016.9 56474.299999999996 46500.3 50337.93000000001 61893.700000000004 44454.6 True False 60310.223478466956 60703.11945624419 58899.51344975191 47092.44918372057 53663.27804153836 54059.02583702323 48907.858006284696 52676.81399544823 54922.57973644479 52138.51837796889 1.1567306734966796 1.1642662918840108 1.1296737092291422 0.9032180170969236 1.0292443995534357 1.0368347148864485 0.9380369739649275 1.0103243366751826 1.0533974007142541 1.0 15.670061965891895 -5.622064268917718 7.099592556147448 0.9972819222261737 1.1570702757537723 0.7333609197264537 0.04287868304900903 0.10730887389760203 6.621856964331208 0.011636754575454343 0.020261793922197752 2.3874579496363143e-06 5.622064268917718 0.15978835352759857 TCNSPQNS(ph)TDSVSDIVPDSPFPGALGSDTR ddPTM_PC-9_AZD4547_30min_R2 1 TCNSPQNSTDSVSDIVPDSPFPGALGSDTR 30 0 Q14694;Q14694-3;Q14694-2 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 T(0.071)CNS(0.335)PQNS(0.59)T(0.004)DSVSDIVPDSPFPGALGSDTR 149.97 5.8313e-15 7014300.0 8892.2 6709.0 9928.1 12395.0 11691.0 7681.8 7984.3 13066.0 6953.0 12886.0 True False 11719.734630749981 8877.553048354379 9796.4469070947 9537.52425084102 10067.90645134938 7201.45583163818 8694.887232361387 11046.949926810492 7320.521385169169 12434.865062193145 0.9424898921004426 0.7139243573575731 0.7878209259286401 0.7669986126217666 0.8096514438230419 0.5791342162234976 0.6992345464847259 0.8883851872584884 0.5887093545893327 1.0 13.602103231683197 -11.084412522398393 3.1874004671198506 1.0098815436310102 0.7521822030321542 0.31314287829133736 0.10977100011315317 256253869.76344204 265486271.51300302 21313647.457273863 0.02638974381634352 8.233556643229637e-12 11.084412522398393 -0.257699340598856 TCPSLS(ph)PTSPLNNK ddPTM_PC-9_AZD4547_30min_R2 2 TCPSLSPTSPLNNK 14 0 O75925;O75925-2 O75925 PIAS1 E3 SUMO-protein ligase PIAS1 1 TCPS(0.01)LS(0.98)PT(0.008)S(0.002)PLNNK;T(0.001)CPS(0.015)LS(0.87)PT(0.108)S(0.007)PLNNK 211.13 2.2958000000000003e-11 17390500.0 54141.0 49065.0 70086.0 88595.0 82844.0 73482.0 64090.0 77703.0 68327.0 75206.0 True False 71356.71179724188 64924.30173163022 69156.61384662103 68170.79152910532 71342.54059153111 68887.15892374661 69793.88584121858 65695.78678730725 71938.6257276648 72573.06083092479 0.9832396619385164 0.8946060836938645 0.9529240334472988 0.9393401731797486 0.9830443938108047 0.9492111554208067 0.9617051429568209 0.9052365441821493 0.9912579806336396 1.0 16.14714649776915 -8.440493839708044 8.682797839262482 0.9999679359293041 0.9463216423034521 0.3477826213055587 0.027224955257277465 0.3309007457792865 31.1601382702785 0.02512513673244511 0.006492111678178061 3.6266543047117256e-09 8.440493839708044 -0.05364629362585205 TCPSLS(ph)PTSPLNNK ddPTM_PC-9_Lapatinib_30min_R1 1 TCPSLSPTSPLNNK 14 0 O75925;O75925-2 O75925 PIAS1 E3 SUMO-protein ligase PIAS1 1 TCPS(0.015)LS(0.605)PT(0.289)S(0.091)PLNNK 101.45 0.0017059000000000002 8843400.0 43152.0 37730.0 41832.0 33277.0 38034.0 29685.0 30576.0 34527.0 29738.0 22102.0 True False 42536.644566892384 37642.63850312427 38392.7344361897 35724.301588817805 35796.91489772104 28415.441749114816 32159.075670482984 36131.25046701044 26388.593284977214 25922.301250936212 1.6409285639852722 1.4521333634206093 1.4810696806790293 1.3781300218292765 1.3809312125183406 1.0961774371049933 1.240594936351244 1.3938288162477672 1.0179880647758524 1.0 14.66190617863397 -1.5228787452803378 0.14355534947974793 0.9314668653861249 3.367107027920707 0.7453657712317024 0.1018712920339477 38.16470231276726 0.36423023325992276 0.4132520156268762 19.16434268244278 0.02999999999999998 1.5228787452803378 2.435640162534582 TCPSLSPT(ph)SPLNNK ddPTM_PC-9_Lapatinib_30min_R1 1 TCPSLSPTSPLNNK 14 0 O75925;O75925-2 O75925 PIAS1 E3 SUMO-protein ligase PIAS1 1 TCPSLS(0.017)PT(0.638)S(0.344)PLNNK 85.976 0.01634 26755000.0 30400.0 29034.0 23947.0 26995.0 26528.0 30959.0 30808.0 25093.0 29714.0 21449.0 True False 29966.490425322776 28966.77355684364 21978.17009809319 28980.302352680133 24967.675196054686 29634.95573895386 32403.08749529826 26258.912386500237 26367.296417708436 25156.43107100401 1.1912059520979894 1.1514659402633443 0.873660100515046 1.1520037270343813 0.9924967148791273 1.1780270283693746 1.2880637719969326 1.0438250287723434 1.0481334312998039 1.0 14.618639641934353 -7.970249283074613 24.996991863610248 1.0313702761013201 1.1128682702267565 0.1204342043207437 0.10819992676129117 490.1770762242846 411853.74468792096 0.061808065149689326 0.029691022518758714 1.0709044344707093e-08 7.970249283074613 0.08149799412543635 TCPSLSPTS(ph)PLNNK ddPTM_PC-9_AZD4547_30min_R2 3 TCPSLSPTSPLNNK 14 0 O75925;O75925-2 O75925 PIAS1 E3 SUMO-protein ligase PIAS1 1 TCPSLS(0.013)PT(0.163)S(0.824)PLNNK;TCPS(0.006)LS(0.003)PT(0.225)S(0.766)PLNNK;TCPSLS(0.219)PT(0.161)S(0.62)PLNNK 185.27 4.0150999999999995e-36 40491000.0 152115.0 138547.0 195225.0 233274.0 212685.0 184860.0 195369.0 237761.0 179356.0 205459.0 True False 200484.4058114452 183329.6083157479 192636.18894225088 179496.283347373 183157.35896033185 173300.67497678043 212756.4625200971 201020.5006542471 188836.39199746883 198265.94294685207 1.0111893289973046 0.9246651522238085 0.971605037552464 0.9053308938464004 0.9237963728820018 0.8740819144276134 1.0730862767345242 1.0138932469513104 0.9524398854930373 1.0 17.597077354921254 -7.260655225404062 24.99884305898395 1.0110126205729266 0.9344274357694284 0.40872192279174724 0.04402790032523598 72.67728711411908 2317003.7644250365 0.017706841178722416 0.01287904244196814 5.48712399932017e-08 7.260655225404062 -0.07658518480349819 TCPSLSPTS(ph)PLNNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TCPSLSPTSPLNNK 14 0 O75925;O75925-2 O75925 PIAS1 E3 SUMO-protein ligase PIAS1 1 TCPSLSPT(0.229)S(0.771)PLNNK 138.31 2.5166999999999998e-05 0.0 9215.2 8654.8 10085.0 13531.0 15271.0 14428.0 13149.0 10805.0 10327.0 9085.8 True False 10775.151351503608 9513.991346419441 10325.464647575485 12772.901938093892 12278.75717379074 13671.37028095761 11903.431529483894 10521.380198843824 10478.012838235449 10732.983616846777 1.003928798939993 0.886425591061746 0.9620311570557474 1.1900606945905707 1.1440208624298722 1.2737716527861518 1.1090514953176627 0.9802847534705248 0.9762441844958079 1.0 13.38976356010665 -5.652791089957657 7.089295982330406 1.1050006508868546 0.940616756757082 0.33415040430049114 0.09352642366180776 0.2531115800448061 14.921645361012466 0.027889699749362683 0.04850914036399739 2.2243796336802204e-06 5.652791089957657 -0.1643838941297726 TCPSLSPTS(ph)PLNNK ddPTM_PC-9_Lapatinib_30min_R1 1 TCPSLSPTSPLNNK 14 0 O75925;O75925-2 O75925 PIAS1 E3 SUMO-protein ligase PIAS1 1 T(0.001)CPS(0.005)LS(0.379)PT(0.073)S(0.542)PLNNK 95.195 0.014427 0.0 17144.0 13256.0 17981.0 13436.0 15760.0 12576.0 12378.0 14658.0 16736.0 11446.0 True False 16899.523416175452 13225.306546446214 16502.671588667217 14424.12826118207 14833.027785352155 12038.153796087849 13018.872273980847 15339.064191659842 14851.015442107031 13424.425849163688 1.2588637760793513 0.9851673877933573 1.2293018542536251 1.074468913847862 1.1049282816274946 0.896735095515299 0.9697898755790657 1.1426234808109452 1.1062682016327883 1.0 13.712572766286963 -1.5228787453784687 0.5133238447279556 1.0399141150402722 6.741518147378237 0.24127355609008172 0.09564542313465194 195.62872016445831 2.0021589033340983 0.05322293679570401 1210.593853680094 0.02999999999322134 1.5228787453784687 5.701604032337965 TCPVQLWVDS(ph)TPPPGTR ddPTM_PC-9_AZD4547_30min_R2 3 TCPVQLWVDSTPPPGTR 17 0 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;E7EQX7;E7EMR6;E9PFT5 J3KP33 TP53 Cellular tumor antigen p53 1 TCPVQLWVDS(0.778)T(0.222)PPPGTR;TCPVQLWVDS(0.785)T(0.214)PPPGTR;TCPVQLWVDS(0.7)T(0.3)PPPGTR 158.14 2.7915e-05 48870000.0 62021.0 59449.0 85285.0 124753.0 91198.0 81797.0 65863.0 91877.0 66855.0 75145.0 True False 81742.38788305983 78664.72666144278 84154.065175771 95993.12326463652 78536.73189206759 76682.2206592868 71724.67940646254 77679.52077342481 70388.81881281237 72514.196422358 1.1272604802368953 1.0848182913489255 1.160518482279204 1.3237838657898906 1.0830531918830268 1.0574787344074283 0.9891122420870953 1.071231905004938 0.970690185999354 1.0 16.145975845065507 -6.59468698573188 3.5992841709817003 1.0204577562213908 1.170043239404135 0.559809551193206 0.06463678609131665 0.19345369885797004 5.030119780672159 0.0232978697495191 0.02361976523259644 2.5428047514045876e-07 6.59468698573188 0.14958548318274412 TCPVQLWVDS(ph)TPPPGTR ddPTM_PC-9_Lapatinib_30min_R1 1 TCPVQLWVDSTPPPGTR 17 0 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;E7EQX7;E7EMR6;E9PFT5 J3KP33 TP53 Cellular tumor antigen p53 1 TCPVQLWVDS(0.5)T(0.5)PPPGT(0.001)R 145.04 3.1006e-05 4333900.0 26235.0 22988.0 30458.0 23762.0 30033.0 29242.0 25864.0 26143.0 29625.0 19578.0 True False 25860.88408909022 22934.77269837851 27953.86081128002 25509.536747708273 28266.517987149804 27991.38782643137 27203.111366476063 27357.699219713693 26288.320534919956 22962.031213954804 1.126245489701002 0.9988128874435234 1.2173949486790834 1.1109442588077862 1.231011216898411 1.219029255975406 1.1846996945959996 1.191432019441185 1.1448604128254845 1.0 14.486962647551014 -5.267495966803488 24.99643358450352 1.172686852736274 1.0625291873968552 0.23019943928419617 0.07111301011176598 524.4821527502316 2164623.3600645894 0.01720623084708593 0.037408071523386294 5.401371308750563e-06 5.267495966803488 -0.11015766533941873 TCPVQLWVDST(ph)PPPGTR ddPTM_PC-9_AZD4547_30min_R2 1 TCPVQLWVDSTPPPGTR 17 0 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;E7EQX7;E7EMR6;E9PFT5 J3KP33 TP53 Cellular tumor antigen p53 1 TCPVQLWVDS(0.234)T(0.766)PPPGTR 149.31 0.00015609 6576900.0 6478.8 4781.1 9652.5 13697.0 11592.0 10809.0 8514.8 8056.6 6613.6 9846.5 True False 8538.923632588441 6326.497075493678 9524.501543168542 10539.368266540498 9982.650892484997 10133.1115212811 9272.600704646718 6811.637592250227 6963.181394068001 9501.77703204135 0.8986659657234611 0.6658225144791154 1.002391606438518 1.109199703487068 1.0506088344129811 1.0664438333072646 0.9758806877259047 0.716880386614042 0.7328293823973304 1.0 13.213981637638755 -2.3410416614069685 0.00560559818657159 0.8209383368400762 1.03198129617392 0.0 0.15234467479457145 3753473.8731723665 1874.6709317576688 32825.49305947156 37919.36649917313 0.00455993170914034 2.3410416614069685 0.21104295933384387 TCPVQLWVDST(ph)PPPGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TCPVQLWVDSTPPPGTR 17 0 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;E7EQX7;E7EMR6;E9PFT5 J3KP33 TP53 Cellular tumor antigen p53 1 TCPVQLWVDS(0.222)T(0.778)PPPGTR;TCPVQLWVDS(0.233)T(0.767)PPPGTR;TCPVQLWVDS(0.174)T(0.825)PPPGT(0.001)R;TCPVQLWVDS(0.21)T(0.79)PPPGTR 193.3 1.2554999999999999e-11 39952400.0 51831.3 59446.0 63638.0 62815.0 70898.0 60712.0 67476.0 60738.0 64319.0 45863.399999999994 True False 60605.31537516157 65347.406015072556 65155.37126845897 59295.67919897774 57006.04584555139 57528.15584263224 61084.18479606484 59143.691857230566 65259.54369540674 54178.07136552533 1.1186318347560456 1.206159694651931 1.2026151840819999 1.0944590256623432 1.0521977694803208 1.0618346942345873 1.1274706399928074 1.09165369616433 1.2045379625110242 1.0 15.725421416852457 -5.772191693141572 24.543479008234595 1.0929007367395758 1.1788379801223736 0.3384950645601307 0.054635998265229774 184.43149350111005 420987.9135655242 0.01519511970865894 0.022808543420250096 1.68969495295468e-06 5.772191693141572 0.08593724338279785 TCPVQLWVDST(ph)PPPGTR ddPTM_PC-9_Lapatinib_30min_R1 3 TCPVQLWVDSTPPPGTR 17 0 J3KP33;P04637;P04637-3;P04637-2;A0A087WZU8;P04637-8;A0A0U1RQC9;E7ESS1;P04637-7;P04637-5;P04637-6;P04637-4;P04637-9;E7EQX7;E7EMR6;E9PFT5 J3KP33 TP53 Cellular tumor antigen p53 1 TCPVQLWVDS(0.25)T(0.73)PPPGT(0.02)R;TCPVQLWVDS(0.215)T(0.785)PPPGTR;TCPVQLWVDS(0.079)T(0.921)PPPGTR 281.61 3.358899999999999e-83 39576900.0 73697.7 56581.1 68475.5 56926.9 65009.6 74210.9 59225.9 52128.7 61591.7 44725.1 True False 72646.75728349689 56450.089939282436 62845.70871307394 61113.49412857145 61185.863141791204 71037.07280105723 62292.327307445696 54550.78970717549 54654.59415664576 52455.77394255033 1.3849144111963683 1.076146355234539 1.1980703741384635 1.165047992533731 1.1664276121214432 1.3542279040407865 1.1875208890382283 1.0399387065934749 1.0419176012254359 1.0 15.678813962262621 -7.742864019272649 4.491247671136504 1.0274328587547439 1.215275316668722 0.5134625577088369 0.08587005193756635 0.16814490977444518 8.058321120385898 0.045042349876759966 0.023160786969371756 1.8077400538271348e-08 7.742864019272649 0.18784245791397813 TCS(ph)FGGFDLTNR ddPTM_PC-9_AZD4547_30min_R2 2 TCSFGGFDLTNR 12 0 O94885;A0A1B0GWB9 O94885 SASH1 SAM and SH3 domain-containing protein 1 1 T(0.014)CS(0.984)FGGFDLT(0.001)NR;T(0.055)CS(0.945)FGGFDLTNR 93.649 0.0052028 28710000.0 43272.0 46247.0 53308.0 82471.0 59945.0 53874.0 49146.0 50059.0 49024.0 51625.0 True False 57031.59588648627 61195.43834062373 52601.101089171556 63458.58511424852 51622.671476019044 50505.25026343768 53519.89879158256 42323.53179138271 51615.308555520394 49817.62446342708 1.1448076157937885 1.228389330076337 1.0558733310896413 1.2738179669894891 1.036233100876119 1.0138028620878021 1.0743165570023006 0.849569449511868 1.0360853033731678 1.0 15.604368608343298 -6.443953100599102 5.872130370557436 0.9936468296701276 1.170671364270642 0.5628566153781887 0.07577946482260106 0.17001138087627982 9.848309725148232 0.023117611544706793 0.026065767993486096 3.597881865343164e-07 6.443953100599102 0.17702453460051426 TCS(ph)FGGFDLTNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TCSFGGFDLTNR 12 0 O94885;A0A1B0GWB9 O94885 SASH1 SAM and SH3 domain-containing protein 1 1 T(0.007)CS(0.993)FGGFDLTNR;T(0.046)CS(0.954)FGGFDLTNR;T(0.006)CS(0.994)FGGFDLTNR;T(0.005)CS(0.994)FGGFDLT(0.001)NR 137.62 6.697e-05 41861400.0 74818.0 73556.0 67469.0 76749.0 89505.0 88073.0 80027.0 70745.0 70503.0 67593.0 True False 87483.20967714179 80858.15356533132 69077.71683760724 72449.00235361516 71967.13776701853 83454.29683634458 72446.26321469386 68888.01871052357 71533.97299642829 79847.07583410632 1.0956344833328728 1.012662677006803 0.8651251923254653 0.9073469704030024 0.9013121271534166 1.0451766199896009 0.9073126655910517 0.8627494243326862 0.8958871974854823 1.0 16.284951953662087 -5.0058554763614955 3.8669786221055755 0.9208723635621969 1.0867086573312141 0.50487898206395 0.054706829059889654 0.17176823200756494 5.721645491703066 0.014521100389707026 0.05884105917450591 9.866077523387561e-06 5.0058554763614955 0.1658362937690172 TCS(ph)FGGFDLTNR ddPTM_PC-9_Lapatinib_30min_R1 2 TCSFGGFDLTNR 12 0 O94885;A0A1B0GWB9 O94885 SASH1 SAM and SH3 domain-containing protein 1 1 T(0.228)CS(0.772)FGGFDLTNR;T(0.017)CS(0.983)FGGFDLTNR 131.79 0.00010607 25077000.0 65887.0 62392.0 71018.0 61846.0 66731.0 65825.0 67463.0 70168.0 62379.0 54614.0 True False 64947.43929780394 62247.53515735302 65179.17417740772 66394.36115220803 62806.01377819383 63009.818195569635 70955.90404100582 73428.261440878 55353.2201400092 64053.95713141934 1.013948898809662 0.9717984328374891 1.0175667062017695 1.0365380083542206 0.980517310575128 0.983699072116537 1.1077520768221356 1.1463501199500514 0.8641655038804417 1.0 15.96700007982016 TCS(ph)LPDLSK ddPTM_PC-9_AZD4547_30min_R2 2 TCSLPDLSK 9 0 Q96PY6-4;Q96PY6-2;Q96PY6-6;Q96PY6;Q96PY6-3 Q96PY6-4 NEK1 Serine/threonine-protein kinase Nek1 1 T(0.283)CS(0.692)LPDLS(0.025)K;T(0.245)CS(0.735)LPDLS(0.02)K 110.93 0.0022688 33349000.0 174435.0 175149.0 203792.0 272680.0 226550.0 228720.0 203712.0 226630.0 183806.0 202688.0 True False 229901.7015266041 231762.48902462664 201089.5849246726 209817.83886400398 195097.44303765325 214418.1022432617 221841.97335756422 191609.5409393127 193521.60991261402 195591.95481342572 1.1754149179903963 1.1849285378107899 1.0281076495016939 1.0727324601062873 0.997471717196936 1.096252156423275 1.1342080688808405 0.9796391734112385 0.9894149792470421 1.0 17.577487504289955 -1.5228787452816657 0.4301404768409668 1.0246519885348844 4.523220951058049 0.5035050582392668 0.05251200847371254 72.7203332435585 0.9136960104336265 0.036732518956601956 220.50334327895743 0.029999999999908256 1.5228787452816657 3.498568962523165 TCS(ph)LPDLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TCSLPDLSK 9 0 Q96PY6-4;Q96PY6-2;Q96PY6-6;Q96PY6;Q96PY6-3 Q96PY6-4 NEK1 Serine/threonine-protein kinase Nek1 1 T(0.044)CS(0.953)LPDLS(0.003)K;T(0.151)CS(0.431)LPDLS(0.419)K 141.89 0.0006925 35710000.0 315890.0 279800.0 274500.0 346300.0 380570.0 334970.0 358360.0 311270.0 293010.0 292870.0 True False 369363.9378881066 307576.6948662206 281045.1210470475 326897.93371974863 306000.04044460313 317403.58351901633 324413.5464982779 303099.492317826 297294.7169295406 345965.01264235604 1.0676337906744906 0.8890398844584332 0.81235128055443 0.9448872625096395 0.8844826189431271 0.9174441689776726 0.937706226478002 0.8760986840919588 0.8593201799769021 1.0 18.400266620276852 -4.759593453103166 24.965645170102015 0.8980300275738742 1.0676340075946356 0.5029063000697245 0.04912150974584921 37.4436930991196 506273.02856756287 0.011731829047771154 0.07357104361848239 1.7394283610948054e-05 4.759593453103166 0.16960398002076138 TCS(ph)LPDLSK ddPTM_PC-9_Lapatinib_30min_R1 2 TCSLPDLSK 9 0 Q96PY6-4;Q96PY6-2;Q96PY6-6;Q96PY6;Q96PY6-3 Q96PY6-4 NEK1 Serine/threonine-protein kinase Nek1 1 T(0.002)CS(0.98)LPDLS(0.018)K;T(0.331)CS(0.669)LPDLSK 121.29 0.0016258 66104000.0 633110.0 575098.0 606690.0 587490.0 548946.0 578600.0 548794.0 520940.0 634930.0 447982.0 True False 624081.7353018449 573766.3959149155 556810.2900911239 630695.9744091881 516658.0755493599 553854.6267824775 577207.8680503356 545144.774184969 563417.4972906915 525415.091801507 1.1877879890393641 1.092024962487516 1.0597531338164863 1.200376586532186 0.9833331467085924 1.0541277466611378 1.098574968738041 1.0375506579299316 1.07232834778096 1.0 19.00309811486742 -1.5228787452803376 0.245412159671973 1.0291233434553866 1.8223134897206652 0.35465641779462476 0.054046444212089914 62.676897635452484 0.8456906918945981 0.07131358879321159 20.396156948274015 0.029999999999999995 1.5228787452803376 0.7931901462652786 TCS(ph)PESQQIYGDIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TCSPESQQIYGDIK 14 0 Q4VC44-2;Q4VC44;Q4VC44-4;Q4VC44-3;I3L287;J3KNW1;Q4VC44-5 Q4VC44-2 FLYWCH1 FLYWCH-type zinc finger-containing protein 1 1 T(0.17)CS(0.592)PES(0.238)QQIYGDIK;T(0.13)CS(0.87)PESQQIYGDIK 123.92 3.9717e-05 11242300.0 34031.0 42205.0 39231.0 44927.0 45646.0 34734.0 33933.0 30120.0 27740.0 27893.0 True False 39791.776157112065 46394.83347687207 40166.41582439601 42409.88584529923 36701.99397255269 32912.48789428761 30718.62058635465 29329.38191477795 28145.645021075932 32949.78009913349 1.207649217609149 1.4080468317933375 1.2190192378689746 1.2871067945735553 1.1138767500763345 0.998868210812525 0.9322860575680287 0.8901237527697264 0.8541982658578078 1.0 15.007981216529416 -6.613440886458699 1.367133963706357 0.9054578171956682 1.2976814521754931 0.87323862909175 0.06247197352760282 0.12556175837825873 0.4887140984421201 0.02597399765626568 0.026739423246299972 2.4353372607893397e-07 6.613440886458699 0.39222363497982493 TCS(ph)PESQQIYGDIK ddPTM_PC-9_Lapatinib_30min_R1 2 TCSPESQQIYGDIK 14 0 Q4VC44-2;Q4VC44;Q4VC44-4;Q4VC44-3;I3L287;J3KNW1;Q4VC44-5 Q4VC44-2 FLYWCH1 FLYWCH-type zinc finger-containing protein 1 1 T(0.023)CS(0.977)PESQQIYGDIK;T(0.026)CS(0.941)PES(0.033)QQIYGDIK 161.19 1.9913e-05 18130200.0 29988.0 57442.0 66572.0 52440.0 64711.0 73710.0 59115.0 67485.0 53621.0 52712.0 True False 29560.36562087433 57308.99657822595 61098.70713535147 56296.61253471183 60904.82620672104 70557.59512640226 62175.68544808357 70620.59946610493 47581.63832583778 61823.19896567497 0.47814357903554333 0.9269820639667099 0.9882812303076431 0.9106065922918098 0.9851451756894071 1.1412802363329133 1.005701524481195 1.142299341470738 0.76964050909523 1.0 15.915860686164075 -4.7325554779995125 2.979337017336076 0.9997865192052312 0.35273638629599274 0.6976969754778234 0.10090707011438957 0.260259286642646 2.958858720710759 0.025246014095830226 0.4312104558428208 1.851162406404586e-05 4.7325554779995125 -0.6470501329092384 TCSDGGPSSELAHS(ph)PTNSGK ddPTM_PC-9_Lapatinib_30min_R1 1 TCSDGGPSSELAHSPTNSGK 20 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 T(0.001)CS(0.001)DGGPS(0.008)S(0.052)ELAHS(0.62)PT(0.23)NS(0.087)GK 53.958 0.014879 5381700.0 14317.0 19043.0 24827.0 10940.0 18369.0 18762.0 14274.0 19399.0 21552.0 11912.0 True False 14112.836954583749 18998.90710349843 22785.819894991444 11744.564094770165 17288.571534843497 17959.59299635817 15013.03787678161 20300.34835953126 19124.58680737873 13970.97332825772 1.0101541691471914 1.3598842870218069 1.6309400468831186 0.840640363332137 1.2374636418405864 1.2854933278007954 1.074587827493465 1.4530375144637728 1.36888005996671 1.0 13.770144913320093 -7.760954956198931 24.99983864072436 1.3082190331727934 1.2181505065054266 0.009867589885476202 0.22834831527303195 59.41785345981208 3066980.03767909 0.11463343673856206 0.06098672397832166 1.7339838323497165e-08 7.760954956198931 -0.09006852666736687 TCSDGGPSSELAHS(ph)PTNSGKK ddPTM_PC-9_AZD4547_30min_R2 1 TCSDGGPSSELAHSPTNSGKK 21 1 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 T(0.003)CS(0.003)DGGPS(0.017)S(0.015)ELAHS(0.807)PT(0.099)NS(0.057)GKK 41.31 0.040981000000000004 7282700.0 18984.0 14435.0 39702.0 65976.0 62442.0 46594.0 30931.0 50787.0 34167.0 49040.0 True False 25020.51710826989 19100.8314581898 39175.52553917404 50766.25251903891 53773.00612737644 43680.46981428176 33683.79907871323 42939.03611915848 35972.997866687016 47323.124526614265 0.5287165071739608 0.40362574638214344 0.8278304936763409 1.0727578330228016 1.136294500105013 0.9230259043803437 0.7117830746735594 0.9073584330850725 0.7601568625599943 1.0 15.530257710839908 -5.357982770982582 4.411606224021529 0.9266437504703774 0.4670149791523464 0.6815378408661068 0.12461604647213706 0.12985990116091653 4.2806182064037515 0.0364224342705893 0.08096257540479479 4.385480951935911e-06 5.357982770982582 -0.459628771318031 TCSDGGPSSELAHS(ph)PTNSGKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TCSDGGPSSELAHSPTNSGKK 21 1 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 TCSDGGPS(0.001)S(0.002)ELAHS(0.452)PT(0.233)NS(0.312)GKK 57.36600000000001 0.018061 3103700.0 25729.0 23941.0 37749.0 53168.0 62973.0 64463.0 55938.0 55440.0 56243.0 40499.0 True False 30084.411529086312 26317.704259443068 38649.07932387972 50189.169332981735 50633.892705462975 61082.44679937413 50639.14768395093 53984.75874353553 57065.44747369769 47841.14811009237 0.6288396645468429 0.5501060342214319 0.8078627050283199 1.0490795333231988 1.0583753673499625 1.2767763570140664 1.0584852095819226 1.1284168728414594 1.1928109948862076 1.0 15.545964391845947 -5.629593899614351 1.8714973228729928 1.1296385507761086 0.5781607121002951 0.8864965879725542 0.0761115280810407 0.09917483550697487 0.6951654042174676 0.02220441120094035 0.05248733383615714 2.346421883616159e-06 5.629593899614351 -0.5514778386758136 TCSDGGPSSELAHS(ph)PTNSGKK ddPTM_PC-9_Lapatinib_30min_R1 1 TCSDGGPSSELAHSPTNSGKK 21 1 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 TCSDGGPS(0.001)S(0.004)ELAHS(0.554)PT(0.29)NS(0.151)GKK 73.76 0.00061889 5905600.0 81605.0 50949.0 80596.0 60125.0 79685.0 85775.0 60381.0 54773.0 102710.0 67460.0 True False 80441.29773547563 50831.030720797244 73969.70798955695 64546.79307112029 74998.0849667376 82106.60320129094 63507.23273349798 57317.95353866723 91141.71821575132 79120.37111520038 1.0166951519773835 0.6424518743319156 0.9349009230739831 0.815804983739766 0.9478985488773722 1.037742897865615 0.8026660117788192 0.7244398974723144 1.1519374458323468 1.0 16.271761572643484 -8.272481707345849 24.86757519188963 1.0759687333198884 0.8649755350180476 0.3187292215068379 0.12318399953640412 899.6910485937856 2026100.8997239936 0.1123626110602662 0.030128717044280412 5.3397176420094745e-09 8.272481707345849 -0.21099319830184082 TCSDGGPSSELAHSPT(ph)NSGKK ddPTM_PC-9_AZD4547_30min_R2 1 TCSDGGPSSELAHSPTNSGKK 21 1 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 TCSDGGPSS(0.001)ELAHS(0.126)PT(0.597)NS(0.276)GKK 68.525 0.008768000000000001 5684700.0 33886.0 33430.0 79655.0 141210.0 120060.0 93691.0 65138.0 94708.0 69811.0 98347.0 True False 44661.04312741435 44235.593740719465 78598.72265434758 108656.2161727519 103391.74138645153 87832.4869590478 70935.15581097358 80073.05477333283 73501.06693801882 94903.90146449716 0.47059227743257437 0.4661093280476743 0.8281927448867924 1.1449077908920253 1.0894361537405246 0.9254886849083362 0.7474419356459217 0.8437277449893623 0.774478876039833 1.0 16.53417977667766 -5.321685751191458 4.009006867834666 0.9275536091031243 0.4622367799587173 0.6981216001399922 0.11989304683814801 0.12898816210323016 4.181020419824524 0.03628010111496213 0.08544574363404457 4.767758496946264e-06 5.321685751191458 -0.46531682914440703 TCSDGGPSSELAHSPTNS(ph)GKK ddPTM_PC-9_Lapatinib_30min_R1 1 TCSDGGPSSELAHSPTNSGKK 21 1 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 TCSDGGPS(0.007)S(0.017)ELAHS(0.174)PT(0.292)NS(0.509)GKK 43.946000000000005 0.030887 6231700.0 27330.0 16103.0 26468.0 19057.0 28069.0 33031.0 21059.0 20277.0 35412.0 20420.0 True False 26940.269188291815 16065.714492865369 24291.903209434622 20458.515352288403 26418.036605777255 31618.34112902177 22149.33197752163 21219.143444827845 31423.527655108377 23949.569792060312 1.124874869243913 0.6708143249483932 1.0142939276298732 0.8542331043904908 1.1030693592890877 1.3202049725128584 0.9248321439521017 0.885992676656027 1.3120706521219354 1.0 14.547712120503157 -6.268710786844974 24.31409131764543 1.088476970647759 0.9055540648929125 0.19720023729049985 0.1723877027206803 632.5616399777441 2115152.2654689876 0.05243390002242267 0.06071473443894356 5.386283561452339e-07 6.268710786844974 -0.1829229057548466 TCSPASLS(ph)QASADLEATLR ddPTM_PC-9_Lapatinib_30min_R1 1 TCSPASLSQASADLEATLR 19 0 A0A3B3IUA7;Q14258 A0A3B3IUA7 TRIM25 E3 ubiquitin/ISG15 ligase TRIM25 1 TCSPAS(0.003)LS(0.887)QAS(0.109)ADLEAT(0.001)LR 81.788 0.018612 0.0 2939.4 2891.2 2883.5 2223.6 2660.0 2276.3 2072.3 905.96 2626.1 2121.9 True False 2897.483616980059 2884.5056040347995 2646.4297606318837 2387.130961712153 2503.544029761214 2178.947955314471 2179.593554158227 948.0542089695832 2330.3209639410425 2488.6675877459734 1.164271046582142 1.159056202699752 1.0633922238802482 0.9592004064609594 1.0059776733897654 0.8755480105271832 0.8758074259858547 0.3809485098121326 0.9363729312084029 1.0 11.281157826537031 -6.444413919676198 0.8743620799109992 0.751042614584058 1.1481863704819955 0.40210245589444527 0.1626770386469668 0.5431187218696331 0.9090490419111691 0.08839622845246395 0.11712548519428598 3.594066267024473e-07 6.444413919676198 0.3971437558979375 TDALTS(ph)SPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDALTSSPGR 10 0 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 TDALT(0.052)S(0.474)S(0.474)PGR 70.942 0.034463 33663000.0 144130.0 258730.0 210080.0 162910.0 193610.0 124280.0 191750.0 96818.0 117330.0 119800.0 True False 168528.3623027404 284415.0045129987 215089.10393283624 153782.6808613465 155673.5103410138 117762.53801756394 173586.05185022004 94276.63008715052 119045.72928344803 141518.7916637215 1.190855011701904 2.00973313274769 1.5198624960276181 1.086659086425544 1.1000200645503455 0.832133574863984 1.2265936545211404 0.6661774664609326 0.8412008602103231 1.0 17.110634109402305 -5.808308159914746 2.6864250487139736 0.9427658412418073 1.6387086705918916 0.5924335826976402 0.23394836421597182 0.17193015755924024 2.525973100138164 0.06730377681168359 0.11636063760435056 1.5548619653523457e-06 5.808308159914746 0.6959428293500843 TDALTSS(ph)PGR ddPTM_PC-9_AZD4547_30min_R2 2 TDALTSSPGR 10 0 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 TDALT(0.013)S(0.104)S(0.883)PGR;TDALT(0.001)S(0.004)S(0.995)PGR 100.82 0.0038406 84582000.0 425250.0 578330.0 590640.0 474200.0 471570.0 652590.0 575830.0 689370.0 612120.0 464780.0 True False 560470.6542505159 765263.8626404514 582807.7276826797 364880.51631696726 406100.6453907123 611783.444136629 627077.7544694797 582843.7066466663 644475.413532252 448508.19366802124 1.2496330327141525 1.706242769796281 1.2994360770007802 0.813542587333524 0.9054475506222338 1.3640407305233349 1.3981411339245964 1.2995162961907405 1.436931192408232 1.0 18.774774816005525 -14.522762237981704 0.02067165979535668 1.3358892085462893e-06 2.1252166941942177 0.0481765555828122 0.24960974341495448 15032.711472793324 23.43188116964242 1641.0399592379506 877.9712348113762 3.000804911868386e-15 14.522762237981704 2.125215358305009 TDALTSS(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TDALTSSPGR 10 0 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 TDALT(0.02)S(0.215)S(0.764)PGR;TDALT(0.021)S(0.186)S(0.793)PGR 98.898 0.0045817 63724000.0 375040.0 682570.0 504430.0 350520.0 454110.0 264142.0 399520.0 250998.0 282050.0 309632.0 True False 438526.86462235294 750331.0386520233 516457.524261428 330881.50080117275 365130.40535591025 250289.9285245842 361674.573325683 244409.56845436443 286174.44766382355 365765.8305544361 1.198927915047789 2.051397303883347 1.4119895329713277 0.904626603036197 0.9982627540752983 0.6842900774662004 0.9888145450258395 0.6682132338165183 0.7823979818728116 1.0 18.48056078081872 -5.6910856611088 3.3750537270746284 0.8446106142040082 1.6476180975097403 0.6737236018375781 0.22369213654250117 0.12005007329651322 2.726293490861643 0.059428159304338146 0.1075570428220173 2.036640327090522e-06 5.6910856611088 0.8030074833057321 TDALTSS(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 2 TDALTSSPGR 10 0 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 TDALTS(0.004)S(0.996)PGR;TDALT(0.004)S(0.031)S(0.965)PGR 117.14 0.00098213 92089000.0 328430.0 515120.0 425390.0 395500.0 527150.0 480070.0 556080.0 596610.0 464310.0 449050.0 True False 323746.52797331463 513927.2712888779 390416.07625288673 424586.38934932294 496144.07341677614 459538.52519782825 584871.1014796627 624330.6786318857 412014.51839894353 526667.6941784859 0.6147073981408817 0.9758093708225621 0.7412949010701538 0.8061751158130311 0.9420438711181601 0.872539801239626 1.1105125830661864 1.1854356846507128 0.7823045213388639 1.0 19.006533441660004 -6.636732536821397 1.4126435180203296 1.0253733763822195 0.7927339354422525 0.35421952056937644 0.1328252773546316 0.4526377359278534 1.8792819488503842 0.05680608319612017 0.05722688808547148 2.3081682520367674e-07 6.636732536821397 -0.23263944093996702 TDANESSS(ph)SPEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDANESSSSPEIR 13 0 Q96JM7-2;Q96JM7 Q96JM7-2 L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 1 TDANES(0.004)S(0.015)S(0.607)S(0.374)PEIR 73.38600000000001 0.021401 6708700.0 11513.0 15066.0 13997.0 15618.0 15555.0 14345.0 16438.0 13303.0 11569.0 13403.0 True False 13461.923507884909 16561.65291227472 14330.7415639181 14742.974094239178 12507.109412501799 13592.722947070763 14880.873639185982 12953.810345693597 11738.174738602296 15832.857801910373 0.850252283972424 1.0460305473264853 0.905126651373637 0.9311631721002578 0.7899464246431056 0.8585135492993995 0.939872878627791 0.818159962513565 0.7413806708467995 1.0 13.950634062347998 -6.118082897127502 7.6213381071523525 0.8530905670322803 0.9406315760485241 0.16456789239586067 0.08208310308473356 0.4421293547927968 26.077263604894036 0.02368071876716823 0.03067694819900391 7.619335600263728e-07 6.118082897127502 0.08754100901624384 TDANESSSS(ph)PEIR ddPTM_PC-9_AZD4547_30min_R2 2 TDANESSSSPEIR 13 0 Q96JM7-2;Q96JM7 Q96JM7-2 L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 1 TDANES(0.05)S(0.031)S(0.338)S(0.58)PEIR;TDANES(0.003)S(0.001)S(0.013)S(0.982)PEIR 151.07 0.00013144 12060200.0 29945.0 33441.0 47882.0 52440.0 41259.0 45314.0 54336.0 53411.0 44332.0 42323.0 True False 39466.887105306705 44250.14927560272 47247.053394456976 40350.7681899236 35530.90003218065 42480.50841662798 59171.79873722035 45157.557212679894 46675.29901442825 40841.2846521186 0.9663478375247287 1.083466145899191 1.1568454272901056 0.9879896906678336 0.869975083664209 1.0401364398419908 1.4488231514076744 1.1056840546845381 1.142846005261664 1.0 15.317740626080834 -7.032556082409502 24.870629901534592 1.1919073944625078 1.0166142030176757 0.2653174649547596 0.12714508189846876 789.4453911470222 603080.0279031307 0.048972345764340765 0.037966966549295926 9.277776742665915e-08 7.032556082409502 -0.17529319144483213 TDANESSSS(ph)PEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDANESSSSPEIR 13 0 Q96JM7-2;Q96JM7 Q96JM7-2 L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 1 TDANES(0.025)S(0.025)S(0.202)S(0.747)PEIR 126.56 0.00012778 6324200.0 22295.0 24782.0 25009.0 25347.0 27478.0 25535.0 24257.0 22994.0 24365.0 25167.0 True False 26069.10315367794 27242.1931814677 25605.309407160654 23926.889766082753 22093.88315247344 24195.8996482016 21959.201354528184 22390.431864156864 24721.292030948644 29729.57787813761 0.8768743121929259 0.9163329964903716 0.8612738974000085 0.8048176756548565 0.7431616837291434 0.8138662360892336 0.7386314546590462 0.7531365549802249 0.8315386155929265 1.0 14.85961135852185 -5.651808705761815 3.1371912210711135 0.7955161572739845 0.895645955811856 0.16060761300372184 0.07217844865860705 0.32754180548584816 6.376599329059643 0.01915183833382756 0.03611530101394755 2.22941692711764e-06 5.651808705761815 0.10012979853787152 TDANESSSS(ph)PEIR ddPTM_PC-9_Lapatinib_30min_R1 2 TDANESSSSPEIR 13 0 Q96JM7-2;Q96JM7 Q96JM7-2 L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 1 TDANES(0.025)S(0.014)S(0.199)S(0.762)PEIR;T(0.002)DANES(0.025)S(0.025)S(0.189)S(0.759)PEIR 107.46 0.0010049 14326000.0 37045.0 38913.0 44751.0 41801.0 43168.0 49509.0 39912.0 44709.0 51572.0 38251.0 True False 36516.73150677902 38822.89933930759 41071.74552385552 44875.18498404824 40628.943111553424 47391.61548111591 41978.44806908415 46786.34335822895 45763.4182827643 44862.63438374629 0.8139676148846268 0.865372706542911 0.9155000834889846 1.0002797562041184 0.9056299004650799 1.0563716583323486 0.9357107233161707 1.0428799824376702 1.020078711635899 1.0 15.45322671911711 -3.736227758351404 0.43487104752409533 1.015178205005829 0.3590091342084568 0.7005348787106949 0.04189081488860216 6.473857405878093 0.4732047569025403 0.027343775364653194 2.6523053203851594 0.00018355754545707276 3.736227758351404 -0.6561690707973721 TDASS(ph)ASSFLDSDELER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDASSASSFLDSDELER 17 0 G3XAC6;Q14498-2;Q14498;H0Y4X3;Q14498-3;A0A0U1RQH7;A0A0U1RQW2 G3XAC6 RBM39 RNA-binding protein 39 1 T(0.003)DAS(0.053)S(0.657)AS(0.215)S(0.071)FLDSDELER 92.95200000000001 0.0019588 2264300.0 2871.8 2667.2 2415.0 2482.0 3616.3 2241.8 2794.8 2225.5 3582.9 1114.2 True False 3357.9390193645345 2931.9819890892836 2472.582758938502 2342.94158675257 2907.7119748267614 2124.2360615366483 2530.05631140023 2167.082983112163 3635.2931343191412 1316.1956399976525 2.551246119741381 2.227618676122125 1.8785830037720777 1.7800861175598095 2.2091791573112545 1.6139212112421502 1.92224942441288 1.6464748227824462 2.7619701994496997 1.0 10.362158232608012 -11.50842805218513 2.869676276308852 0.06311208656113355 2.03094407592261 0.4384424489836086 0.3598951074085339 92423156.66246401 79531097.10249689 574679528.7069496 0.08838206700382217 3.1015011591595805e-12 11.50842805218513 1.9678319893614762 TDASS(ph)ASSFLDSDELER ddPTM_PC-9_Lapatinib_30min_R1 1 TDASSASSFLDSDELER 17 0 G3XAC6;Q14498-2;Q14498;H0Y4X3;Q14498-3;A0A0U1RQH7;A0A0U1RQW2 G3XAC6 RBM39 RNA-binding protein 39 1 TDAS(0.135)S(0.638)AS(0.197)S(0.029)FLDSDELER 123.63 4.2206e-05 2446500.0 7368.8 5733.7 6762.1 7525.8 5390.7 6675.5 5377.3 5104.3 5856.2 4857.8 True False 7263.7195607275835 5720.423969927476 6206.146240460852 8079.272437332843 5073.629624523973 6390.004426350545 5655.71028266903 5341.4644121632755 5196.613087480111 5697.464257388373 1.274903927884781 1.0040298124747915 1.0892821718737118 1.4180470595942365 0.8905066175614139 1.1215523499009403 0.992671481060158 0.9375160897651191 0.9120922664396242 1.0 12.476104253542692 -6.815475205834348 1.2100627675130444 0.9535480651629666 1.161995734395603 0.3206522642278724 0.13180793729578297 0.5885658872210121 1.811760151289726 0.06815700620660736 0.05838596031800253 1.5294130591521557e-07 6.815475205834348 0.20844766923263647 TDASSAS(ph)SFLDSDELER ddPTM_PC-9_AZD4547_30min_R2 1 TDASSASSFLDSDELER 17 0 G3XAC6;Q14498-2;Q14498;H0Y4X3;Q14498-3;A0A0U1RQH7;A0A0U1RQW2 G3XAC6 RBM39 RNA-binding protein 39 1 TDASSAS(0.5)S(0.5)FLDSDELER 364.82 3.447299999999999e-266 2176700.0 7569.6 6622.9 10919.0 15217.0 11174.0 12831.0 10767.0 11252.0 9883.4 9134.3 True False 9976.575342538978 8763.622907131647 10774.206925652143 11708.955750306402 9622.682977279796 12028.675541637318 11725.242141557195 9513.261945237386 10405.816346639003 8814.510937264535 1.131835380719951 0.9942267891553969 1.2223261168243298 1.3283727065111703 1.0916865434471927 1.3646446895634865 1.3302203860213222 1.0792728051443883 1.1805324675073021 1.0 13.105664810196586 -5.2766437324779245 24.1775214907074 1.2137630203741427 1.0630310890698695 0.16915825175985688 0.11781067650356516 696.6852613286745 1107848.9777372908 0.03033904891193884 0.06355546878594988 5.288789324477603e-06 5.2766437324779245 -0.1507319313042732 TDASSASS(ph)FLDSDELER ddPTM_PC-9_AZD4547_30min_R2 1 TDASSASSFLDSDELER 17 0 G3XAC6;Q14498-2;Q14498;H0Y4X3;Q14498-3;A0A0U1RQH7;A0A0U1RQW2 G3XAC6 RBM39 RNA-binding protein 39 1 TDASSAS(0.02)S(0.979)FLDSDELER 166.04 2.4753000000000002e-05 3184100.0 8278.6 6573.4 9684.2 13788.0 12336.0 11500.0 8892.8 12648.0 10320.0 11151.0 True False 10911.022594422842 8698.123000156898 9555.781180456132 10609.389622476478 10623.359334859811 10780.903182045753 9684.241972363683 10693.542222126058 10865.494131302426 10760.606884100247 1.0139783668284406 0.8083301521784192 0.8880336660728353 0.9859471437575509 0.9872453709424855 1.0018861666599395 0.899971728051232 0.9937675762439308 1.0097473356597721 1.0 13.39347182584468 -5.761397009509292 24.99999999998575 0.9799402902179924 0.8939356546359875 0.2983614369240365 0.05497406222111045 1.2655956517503333 745438.6955761501 0.014837158271002722 0.023730127035494656 1.7322197682094037e-06 5.761397009509292 -0.086004635582005 TDASSASS(ph)FLDSDELER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDASSASSFLDSDELER 17 0 G3XAC6;Q14498-2;Q14498;H0Y4X3;Q14498-3;A0A0U1RQH7;A0A0U1RQW2 G3XAC6 RBM39 RNA-binding protein 39 1 TDAS(0.001)S(0.007)AS(0.143)S(0.848)FLDSDELER 231.41 2.3015999999999993e-96 0.0 3967.7 4485.9 5762.6 5523.7 5839.6 5244.9 5209.3 5228.1 4522.6 4942.8 True False 4639.3532443529 4931.230505719716 5900.002238782198 5214.224997077023 4695.3722999193515 4969.848210881244 4715.837391934023 5090.867914629839 4588.734469081399 5838.890512816728 0.79456075330908 0.8445492332653538 1.0104663250374923 0.8930164019399703 0.804154880043172 0.8511631105211029 0.8076598424961843 0.8718896001654881 0.7858915078145139 1.0 12.511478543540848 -6.217224820024901 23.49445229883304 0.8446494596439739 0.8916281707274859 0.0318172254583734 0.07559214787941115 635.7477674046163 337817.9243057048 0.022043887039369867 0.028458339244227596 6.064223233509901e-07 6.217224820024901 0.04697871108351204 TDASSASS(ph)FLDSDELER ddPTM_PC-9_Lapatinib_30min_R1 1 TDASSASSFLDSDELER 17 0 G3XAC6;Q14498-2;Q14498;H0Y4X3;Q14498-3;A0A0U1RQH7;A0A0U1RQW2 G3XAC6 RBM39 RNA-binding protein 39 1 TDASSAS(0.023)S(0.977)FLDSDELER 253.1 1.6383e-57 2431200.0 3746.4 5002.6 7786.9 4636.7 4653.2 6126.5 4272.1 3329.5 3359.2 3857.2 True False 3692.975648994383 4991.0167870588275 7146.691140303253 4977.698385577769 4379.507924543184 5864.483876569036 4493.28843445416 3484.2007249373355 2980.8515220558043 4523.911880604069 0.8163235152363904 1.1032524325810669 1.5797591396384514 1.1003084314969254 0.9680798477353183 1.2963302626898123 0.9932307598029916 0.7701743130487541 0.6589101646378173 1.0 12.143355112607491 -7.579596305815057 3.8375044532970084 0.7887462216533486 1.152408678280868 0.34613196935618173 0.20463358940321794 0.24742566132559782 7.4990153827398895 0.10625600589902509 0.05920826802967401 2.6327140684503117e-08 7.579596305815057 0.3636624566275194 TDASSASSFLDSDELER ddPTM_PC-9_AZD4547_30min_R2 2 TDASSASSFLDSDELER 17 0 G3XAC6;Q14498-2;Q14498;H0Y4X3;Q14498-3;A0A0U1RQH7;A0A0U1RQW2 G3XAC6 RBM39 RNA-binding protein 39 0 ; 242.07 1.025e-37 4091000.0 2569.5 3355.16 5177.5 6679.9 5642.5 6260.799999999999 3125.79 5831.4 6473.799999999999 5027.2 False True 3386.547551079832 4439.649856270182 5108.842967081596 5139.952258426214 4859.136271639626 5869.311186274097 3403.979254542402 4930.29112224114 6815.991851475359 4851.19925816059 0.6980846118375883 0.9151654302391088 1.05310928189305 1.0595219831013722 1.0016360930682624 1.209868091153102 0.7016778889913244 1.0163035694622322 1.4050117277721863 1.0 12.244125722668599 -4.818368741268494 2.0165494621861515 1.0482647533265992 0.6119225836264797 0.30386415513416953 0.16722214904411078 0.8833532457183253 4.23875689204399 0.045199228563741194 0.702942987875283 1.5192570443890191e-05 4.818368741268494 -0.4363421697001195 TDASSASSFLDSDELER ddPTM_PC-9_Lapatinib_30min_R1 2 TDASSASSFLDSDELER 17 0 G3XAC6;Q14498-2;Q14498;H0Y4X3;Q14498-3;A0A0U1RQH7;A0A0U1RQW2 G3XAC6 RBM39 RNA-binding protein 39 0 ; 267.93 8.437599999999999e-69 4842200.0 7485.4 6992.0 11220.2 6813.4 8557.6 5699.3 6179.1 6061.2 8464.4 5835.3 False True 7378.65682334576 6975.8104535872035 10297.718467224506 7314.480164836104 8054.258792888933 5455.554224717198 6499.023563431498 6342.825479498474 7511.0501379165125 6843.923829951501 1.0781325167667812 1.019270615353508 1.5046512385421273 1.068755343656117 1.1768481054158677 0.7971383610147307 0.9496048940506038 0.9267820094285623 1.0974771672714159 1.0 12.7406079879782 -6.732938467566892 24.43720084816382 0.9493371583457987 1.1742029938581917 0.3644593576672852 0.14203567146151502 181.91037720174035 155972.59801251465 0.04728215035175401 0.04727246903022725 1.8495306486925022e-07 6.732938467566892 0.22486583551239303 TDATDGKDYNAS(ph)ASTISPPSSMEEDKFSR ddPTM_PC-9_AZD4547_30min_R2 1 TDATDGKDYNASASTISPPSSMEEDKFSR 29 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TDATDGKDY(0.008)NAS(0.32)AS(0.32)T(0.32)IS(0.029)PPS(0.001)SMEEDKFSR 46.861999999999995 0.007308499999999999 19255000.0 60179.0 57053.0 75170.0 78446.0 78300.0 92856.0 70819.0 77807.0 76181.0 82089.0 True False 79314.67019903999 75494.26651777633 74173.19668479449 60361.48667861837 67429.39655638151 87049.69964104703 77121.75380541843 65783.71597698958 80207.77213340616 79215.08909594714 1.0012570976594148 0.9530288658305481 0.9363518684546854 0.7619948089120641 0.851219096335415 1.0989030074259012 0.9735740335027179 0.8304442591399579 1.012531489250194 1.0 16.27348764432982 -6.668798275461044 21.37649015294913 0.9723275344142426 0.8979423016886368 0.17988795283174353 0.0862494777962348 12.93997917787105 2973.208637487751 0.03064705194487468 0.03064699254220413 2.1438861791092863e-07 6.668798275461044 -0.07438523272560582 TDATDGKDYNASAST(ph)ISPPSSMEEDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDATDGKDYNASASTISPPSSMEEDK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TDATDGKDY(0.001)NAS(0.135)AS(0.101)T(0.378)IS(0.378)PPS(0.004)S(0.001)MEEDK 56.485 0.0027895 9125900.0 44503.0 73246.0 45461.0 55494.0 53508.0 36293.0 59333.0 38034.0 29789.0 37316.0 True False 52036.478925684205 80517.37881405001 46544.96265180259 52384.8510939755 43023.49151039191 34389.73118982497 53712.54870627944 37035.64780035409 30224.607769748767 44081.095406706554 1.1804715478501315 1.8265739104523249 1.0558939659362725 1.1883745313190561 0.9760077673534008 0.7801469285763908 1.2184939646056878 0.840170768413333 0.6856591809002631 1.0 15.427872454597077 -5.69706367433516 1.4578086407645763 0.9197854775962968 1.4933115634944583 0.47333514389354847 0.21998802377625726 0.35201393894055033 1.4859547822006955 0.06945599878032857 0.1762673457396904 2.008798269903689e-06 5.69706367433516 0.5735260858981615 TDATDGKDYNASAST(ph)ISPPSSMEEDKFSR ddPTM_PC-9_AZD4547_30min_R2 1 TDATDGKDYNASASTISPPSSMEEDKFSR 29 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TDATDGKDY(0.001)NAS(0.088)AS(0.088)T(0.291)IS(0.291)PPS(0.117)S(0.117)MEEDKFS(0.007)R 52.272 0.0039801 55815000.0 54235.0 51097.0 65696.0 65306.0 57188.0 64893.0 60311.0 66865.0 53494.0 62611.0 True False 71480.60184192036 67613.10599370452 64824.82811499617 50250.71066764209 49248.433336734946 60835.2304515213 65678.56216211159 56532.5506548434 56321.58362983456 60419.0079473052 1.183081355858451 1.1190701120527118 1.0729210941618494 0.8317036703328288 0.8151148952939985 1.006888933108255 1.0870513170191993 0.9356749237615519 0.9321831910738383 1.0 15.882714875411843 -5.563527016447015 6.292515758290744 0.9444577805583055 1.1385465011212368 0.5492144909152299 0.077096469354993 0.14931485901491703 15.437502932017468 0.02350515733056234 0.04169197012926228 2.7319514902605904e-06 5.563527016447015 0.19408872056293125 TDATDGKDYNASASTIS(ph)PPSSMEEDK ddPTM_PC-9_AZD4547_30min_R2 2 TDATDGKDYNASASTISPPSSMEEDK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TDATDGKDY(0.001)NAS(0.013)AS(0.047)T(0.193)IS(0.709)PPS(0.028)S(0.009)MEEDK;TDATDGKDYNASAS(0.019)T(0.091)IS(0.888)PPS(0.001)S(0.001)MEEDK 99.95700000000001 0.00017805 9514300.0 29349.0 48967.0 34639.0 24378.0 30011.6 51114.0 44589.0 39286.0 46608.0 40146.0 True False 38681.37150287683 64794.62514812471 34179.664227279485 18758.0287363455 25845.007377924663 47917.833499746695 48557.33461966135 33215.251402470305 49071.603727882124 38740.50075949138 0.9984737095428468 1.672529365337388 0.8822721327087004 0.4841968577742198 0.6671314740709093 1.2368924655163855 1.2533997668516161 0.8573779572101325 1.2666744818950137 1.0 15.241554981878993 TDATDGKDYNASASTIS(ph)PPSSMEEDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDATDGKDYNASASTISPPSSMEEDK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TDATDGKDYNAS(0.001)AS(0.024)T(0.133)IS(0.799)PPS(0.033)S(0.009)MEEDK 75.184 0.00012128 10698000.0 66032.0 108460.0 70289.0 83833.0 83267.0 48124.0 84056.0 55212.0 56818.0 50513.0 True False 77209.91340855183 119227.1920128311 71964.95633251697 79136.10880025297 66951.42908716078 45600.292722539794 76093.6071672596 53762.743501949546 57648.85576090456 59670.60703931202 1.2939354439227444 1.9980891418497249 1.2060369401823787 1.3262159164581107 1.122016892555694 0.7642002484153972 1.275227636231819 0.9009920657674847 0.9661181379120964 1.0 15.864732833300824 -5.821803958610508 1.3347745960922217 0.9959174369760273 1.6297965345949355 0.5238382682219224 0.22310328318387718 0.33049904005523756 1.1849533177014233 0.07351281023686554 0.16719347082936767 1.5072873051201378e-06 5.821803958610508 0.6338790976189081 TDATDGKDYNASASTIS(ph)PPSSMEEDK ddPTM_PC-9_Lapatinib_30min_R1 1 TDATDGKDYNASASTISPPSSMEEDK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TDATDGKDYNAS(0.002)AS(0.028)T(0.327)IS(0.642)PPSSMEEDK 96.34100000000001 0.00020758 0.0 6318.3 16454.0 13876.0 14726.0 17935.0 15251.0 19650.0 17035.0 14076.0 14193.0 True False 6228.199883365688 16415.90177393074 12735.16884290897 15808.99916449593 16880.09856156667 14598.75028181742 20667.380851811584 17826.50828932496 12490.612653148815 16646.241139016267 0.3741505263171835 0.9861626800211581 0.7650477207770146 0.9497038419948172 1.0140486624336034 0.876999807938632 1.241564427621463 1.0709029227951243 0.7503563446448407 1.0 14.022908820970816 -4.760198986157197 24.99187358148128 0.9650821146506394 0.3741498136144922 0.6256269123537213 0.13631500612737638 20.96327654856409 422204.29235136864 0.034810149545711266 0.20970603507523275 1.7370047810996527e-05 4.760198986157197 -0.5909323010361472 TDATDGKDYNASASTIS(ph)PPSSMEEDKFSR ddPTM_PC-9_Lapatinib_30min_R1 6 TDATDGKDYNASASTISPPSSMEEDKFSR 29 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TDATDGKDY(0.003)NAS(0.01)AS(0.099)T(0.042)IS(0.83)PPS(0.008)S(0.008)MEEDKFSR;TDAT(0.001)DGKDY(0.051)NAS(0.057)AS(0.167)T(0.167)IS(0.544)PPS(0.008)S(0.004)MEEDKFS(0.001)R;TDATDGKDYNAS(0.016)AS(0.209)T(0.209)IS(0.564)PPS(0.002)S(0.001)MEEDKFSR;TDATDGKDYNAS(0.001)AS(0.003)T(0.023)IS(0.676)PPS(0.271)S(0.023)MEEDKFS(0.001)R;TDATDGKDYNASAS(0.007)T(0.057)IS(0.732)PPS(0.147)S(0.056)MEEDKFSR;TDATDGKDYNAS(0.007)AS(0.205)T(0.205)IS(0.504)PPS(0.06)S(0.018)MEEDKFSR 78.484 3.1449e-06 145827000.0 193416.0 239190.0 266934.0 239976.0 284504.0 288301.0 241140.0 251795.0 267845.0 220857.0 True False 190657.8523718498 238636.17025079008 244987.7169150381 257624.63557646904 267770.03407638485 275971.0382924557 253625.04929291818 263494.31492284 237677.47556711046 259031.83817654612 0.7360402246842905 0.9212619264514691 0.9457822584267186 0.9945674531363284 1.0337340612696542 1.0653942783063002 0.9791269331149058 1.0172275222139002 0.9175608575387503 1.0 17.982769908087825 -4.093803074244592 1.0277596119451955 1.00411628384553 1.3347172677648337e-11 0.8121567266706208 0.03794019211944957 2.6642288289075187 0.8308155229195877 0.012338697386590266 4.134478316334698 8.057437134453674e-05 4.093803074244592 -1.0041162838321829 TDCSSGDASRPSSDNADS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 TDCSSGDASRPSSDNADSPK 20 1 Q9NZN5-2;Q9NZN5;E9PMR6 Q9NZN5-2 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 TDCS(0.001)S(0.001)GDASRPS(0.014)S(0.014)DNADS(0.97)PK 51.786 0.019165 5184200.0 9601.9 9575.0 7105.3 8534.5 7174.4 9452.5 10068.0 7159.5 8582.5 5952.7 True False 12655.104468072943 12669.931500669722 7011.07907947945 6567.002881710582 6178.358399158413 8861.433680720655 10964.032495699623 6053.163783943035 9036.153428478987 5744.297784860867 2.2030724976385363 2.2056536717266653 1.2205284861723558 1.1432211782296453 1.0755637382590986 1.5426487296802438 1.9086810792775053 1.0537691482318667 1.5730649362040083 1.0 12.487914825189042 -5.256983045633461 24.57012835360681 1.3312969812085071 2.2043632340312254 0.6319430006209423 0.27135182658130935 188.7750423639985 1040804.1766719079 0.07186803565153387 0.17683726292186774 5.53371711801297e-06 5.256983045633461 0.8730662528227182 TDCSSGDASRPSSDNADS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDCSSGDASRPSSDNADSPK 20 1 Q9NZN5-2;Q9NZN5;E9PMR6 Q9NZN5-2 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 TDCSSGDASRPS(0.003)S(0.003)DNADS(0.993)PK 53.589 0.013538 6691100.0 10587.0 9499.1 8522.9 10941.0 9325.2 7769.0 8916.4 6442.9 6706.6 6661.6 True False 12379.169997218572 10442.107870635133 8726.118259278239 10328.011241200595 7497.9940015083175 7361.579963457144 8071.774042854227 6273.780701816829 6804.671337359334 7869.295346803418 1.5730976474592617 1.3269431900121547 1.1088817835287972 1.312444226076218 0.9528164430318495 0.9354814680386201 1.0257302194322975 0.7972480921516432 0.8647116466563242 1.0 12.942018740574465 -4.004998879432285 0.4092124415240479 0.8758541575586035 2.6147078502660057 0.8105741048336448 0.10026826234168006 4.237909557916658 0.3424994949724575 0.07647175076024643 4.0904226383133535 9.885556453274121e-05 4.004998879432285 1.7388536927074023 TDDEVVQR ddPTM_PC-9_AZD4547_30min_R2 1 TDDEVVQR 8 0 P14625;Q96GW1;A0A1W2PRR1;F8VPC7 P14625 HSP90B1 Endoplasmin 0 116.25 0.01658 3121600.0 14539.0 28335.0 23157.0 27618.0 27511.0 25412.0 24611.0 33266.0 21096.0 26120.0 False True 19162.099570013495 37493.73462887484 22849.923049484994 21251.096793846482 23691.572524426723 23822.983622795386 26801.331322175534 28125.50407663233 22211.09149166242 25205.546750309244 0.7602334422592281 1.487519195687149 0.9065434396579655 0.843111915181358 0.9399348785852485 0.9451484571546976 1.0633108493013235 1.1158458237485867 0.8811985596539347 1.0 14.621453628695559 TDDEVVQR ddPTM_PC-9_Lapatinib_30min_R1 1 TDDEVVQR 8 0 P14625;Q96GW1;A0A1W2PRR1;F8VPC7 P14625 HSP90B1 Endoplasmin 0 102.51 0.019609 5917300.0 39728.0 34295.0 29082.0 40776.0 37530.0 29637.0 40523.0 37810.0 40015.0 29305.0 False True 39161.471434777064 34215.59203457853 26690.9902197664 43774.80306474844 35322.55918681892 28369.494597221343 42621.0826594382 39566.790632191194 35508.08932336955 34370.330203542006 1.13939759097052 0.9954979143916537 0.7765706660861752 1.2736218362032863 1.02770497046836 0.8254065186227902 1.240054500699732 1.1511902969181738 1.0331029441116715 1.0 15.068876091624052 -7.283473800410701 24.992935219978683 1.1186860978512 1.0085451416655782 0.09845020121450798 0.1457652113890981 1918.0798028106099 2175606.8964906125 0.061466224654282975 0.041478608696507935 5.206264155713972e-08 7.283473800410701 -0.11014095618562192 TDDEVVQREEEAIQLDGLNASQIR ddPTM_PC-9_Lapatinib_30min_R1 2 TDDEVVQREEEAIQLDGLNASQIR 24 1 P14625;Q96GW1;A0A1W2PRR1 P14625 HSP90B1 Endoplasmin 0 ; 106.47 3.0403000000000004e-05 1568200.0 7080.5 10156.8 8889.8 10115.1 10977.6 9108.3 8353.2 9296.5 10690.9 8422.5 False True 6979.530771595327 10133.282553631925 8158.914959620365 10858.998196984428 10331.919150791988 8718.75924148433 8785.687823478504 9728.4493285418 9486.778261832096 9878.317902724191 0.7065505322187038 1.0258105330703542 0.8259417281327159 1.0992760411152378 1.045918875312031 0.882615778044551 0.889391079533453 0.9848285329892995 0.9603637335072889 1.0 13.270049682747112 -4.753054710793995 24.997222206567084 0.964700343274027 0.7065500516718611 0.4989657334715123 0.07859699433202917 278.10052095706016 829037.8389684514 0.019753881993510518 0.22086339534442556 1.765815355861767e-05 4.753054710793995 -0.25815029160216585 TDDIPVWDQEFLK ddPTM_PC-9_Lapatinib_30min_R1 1 TDDIPVWDQEFLK 13 0 E5RJR5;P63208;E7ERH2;F8W8N3;P63208-2;E5RGM3 E5RJR5 SKP1 S-phase kinase-associated protein 1 0 113.63 0.0014914000000000001 1288600.0 6812.3 6832.6 6999.4 5635.3 5063.4 5157.4 5924.3 7171.1 4599.1 4162.9 False True 6715.155352777185 6816.779534493689 6423.936350465338 6049.73876080972 4765.580767027417 4936.830024486599 6231.031266177469 7504.295485387628 4081.100927329971 4882.451718284422 1.375365439381494 1.3961796097164365 1.3157193805743475 1.239078051331034 0.9760630605276993 1.0111375000388707 1.2762095000023688 1.5369932809134792 0.8358712308503837 1.0 12.253390062284438 -5.825562812229953 2.8119796012663194 1.1355537439412662 1.3750028715308051 0.27606659071944406 0.18284148035806627 0.401274036569339 6.436607399967403 0.055731341323024056 0.09416165622052332 1.4942979056771115e-06 5.825562812229953 0.23944912758953896 TDDYLDQPCYETINR ddPTM_PC-9_AZD4547_30min_R2 3 TDDYLDQPCYETINR 15 0 P50395;P50395-2;Q5SX87;Q5SX91 P50395 GDI2 Rab GDP dissociation inhibitor beta 0 ;; 191.53 4.0458e-07 11876300.0 21478.0 23766.4 30346.5 40081.0 33280.1 31274.9 31839.3 38024.0 25890.4 32689.5 False True 28307.557229847283 31448.42402271714 29944.08558194915 30840.944695277027 28659.732571341436 29319.275558970694 34672.936019103 32148.264504595314 27258.913687700813 31545.050554909427 0.8973692142472003 0.9969368718549335 0.9492482990263867 0.9776793554853626 0.9085334170396838 0.9294413875779213 1.0991561404775358 1.0191223009338943 0.8641264860315289 1.0 14.945126042442332 TDDYLDQPCYETINR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDDYLDQPCYETINR 15 0 P50395;P50395-2;Q5SX87;Q5SX91 P50395 GDI2 Rab GDP dissociation inhibitor beta 0 116.24 0.00313 0.0 5940.8 5293.6 1779.5 6723.1 6289.9 5349.7 5101.5 4910.4 4629.5 6660.3 False True 6946.46010385153 5819.113623816373 1821.9300287913309 6346.426503584285 5057.439247424953 5069.152314391386 4618.248988338437 4781.50720299886 4697.197679346468 7867.7596670942075 0.882901918433543 0.7396150708764011 0.23156910046595547 0.8066370570681405 0.6428055077199393 0.6442942500636362 0.5869839933791585 0.6077342732006467 0.5970184497363122 1.0 12.941737173596914 -11.536209190102204 2.610137379462523 1.3990425889238804 0.6317152386178249 0.30413057219348094 0.1641684382595756 13248956.00574623 4959187.201137329 31719052.937591504 0.04180100122680307 2.909315427243702e-12 11.536209190102204 -0.7673273503060556 TDDYLDQPCYETINR ddPTM_PC-9_Lapatinib_30min_R1 4 TDDYLDQPCYETINR 15 0 P50395;P50395-2;Q5SX87;Q5SX91 P50395 GDI2 Rab GDP dissociation inhibitor beta 0 ;;; 279.77 1.1187999999999999e-74 26680200.0 72814.0 76318.0 80608.0 73454.0 79642.0 79572.0 78577.0 69847.0 79980.0 65743.0 False True 71775.65900754761 76141.29035996378 73980.72139587837 78856.0521953607 74957.61414219644 76168.89105139165 82645.33257978622 73092.34660900976 70971.81017326246 77106.5899529588 0.930862836125116 0.9874809715540016 0.9594604227863343 1.0226888809824064 0.9721298035346472 0.9878389265802154 1.071832286062793 0.9479390367749624 0.9204376722736792 1.0 16.23456654560635 TDENIDTPGT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 TDENIDTPGTPK 12 0 B8ZZI9;Q6ULP2-7;Q6ULP2-8;Q6ULP2-6;Q6ULP2;Q6ULP2-9;A0A0U1RR74 B8ZZI9 AFTPH Aftiphilin 1 TDENIDT(0.003)PGT(0.997)PK 137.39 0.00016205 8545300.0 41038.0 43680.0 43208.0 42474.0 44732.0 45599.0 45455.0 56512.0 46216.0 42544.0 True False 54087.23035657292 57798.705791044704 42635.03368839434 32682.275516758502 38521.73393052439 42747.68732157431 49500.406941997026 47779.368916570835 48658.88340816602 41054.54750938578 1.3174479719745453 1.4078514877756456 1.0384972256397962 0.7960695586594095 0.9383061382351773 1.0412412245391682 1.2057228722513718 1.163802107565493 1.1852251786977253 1.0 15.325254414119433 -5.265808963146156 24.499762765052328 1.0447048035047704 1.3626497456134912 0.5353490875033005 0.11795447495063238 220.90833084623253 1238618.9007213656 0.0354760408032458 0.07825096265226231 5.422393574453584e-06 5.265808963146156 0.3179449421087208 TDES(ph)SPVLSPR ddPTM_PC-9_AZD4547_30min_R2 1 TDESSPVLSPR 11 0 Q8NA72;Q8NA72-3 Q8NA72 POC5 Centrosomal protein POC5 1 TDES(0.5)S(0.5)PVLSPR 114.76 0.0014259000000000001 6321800.0 27792.0 21361.0 34257.0 35509.0 36381.0 33196.0 24532.0 36155.0 24872.0 33608.0 True False 36629.27789048865 28265.525512877884 33802.72979687384 27322.948658581183 31330.12613177161 31120.248872277465 26715.30047521883 30568.07550924792 26186.683142805614 32431.394149479067 1.1294388925021595 0.8715482714865621 1.0422842028028203 0.8424845547079283 0.9660431490354185 0.9595717263600072 0.8237481358983746 0.942545835937766 0.8074485796727996 1.0 14.985103422748283 -4.753867091909115 24.920637603278188 0.9169906531966229 1.1294392867730942 0.42070365047274916 0.07468012024293558 247.05074722993393 812981.8784527996 0.017433101400063242 0.1793752852180617 1.762515350315713e-05 4.753867091909115 0.21244863357647137 TDES(ph)SPVLSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TDESSPVLSPR 11 0 Q8NA72;Q8NA72-3 Q8NA72 POC5 Centrosomal protein POC5 1 TDES(0.5)S(0.5)PVLSPR;TDES(0.499)S(0.499)PVLS(0.002)PR 151.26 0.00035773 11870400.0 66604.0 70425.0 65258.0 59973.0 66015.0 43691.0 49077.0 44327.0 41187.0 39578.0 True False 77878.74171103691 77416.32857738934 66813.99821234314 56612.90724508937 53079.83464264267 41399.76704639029 44428.07127328931 43163.463218338766 41789.28195685129 46753.17810072437 1.6657421992416448 1.655851681582046 1.4290792824479233 1.21088896081296 1.135320352517817 0.8854963176449574 0.9502684753873655 0.9232198744938371 0.8938276210190689 1.0 15.512776816727577 -5.795045811980733 0.9488886993052025 0.9199952380398132 1.735775364146154 0.9709967891536556 0.049559655876993035 0.09765873742666116 0.1660349660107856 0.01992320656104367 0.05910081499491099 1.6030762796921208e-06 5.795045811980733 0.8157801261063408 TDES(ph)SPVLSPR ddPTM_PC-9_Lapatinib_30min_R1 2 TDESSPVLSPR 11 0 Q8NA72;Q8NA72-3 Q8NA72 POC5 Centrosomal protein POC5 1 TDES(0.5)S(0.5)PVLSPR;TDES(0.5)S(0.5)PVLSPR 177.04 8.7106e-05 13576500.0 84770.0 81696.0 81823.0 65391.0 61950.0 50424.0 43532.0 45449.0 64181.0 43792.0 True False 83561.16425508577 81506.8379313874 75095.82878591404 70200.07227798125 58306.22279838613 48267.48306408506 45785.87395628814 47560.72645973177 56952.25992410798 51361.388850827905 1.6269257145241474 1.5869282306230623 1.462106661562824 1.3667868772370566 1.135215073091745 0.9397620302728054 0.8914454024844795 0.9260015650640866 1.108853580449664 1.0 15.64839659410295 -6.131823941687817 1.3107908670891415 0.9584241197466735 1.5978723745890007 0.9443120791264604 0.0632686172763081 0.09596128415935078 0.3342362589171132 0.025393976710659374 0.04096034200569132 7.382034292098782e-07 6.131823941687817 0.6394482548423271 TDESSPVLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 TDESSPVLSPR 11 0 Q8NA72;Q8NA72-3 Q8NA72 POC5 Centrosomal protein POC5 1 TDESSPVLS(1)PR;TDESSPVLS(0.999)PR 110.64 0.0019117000000000001 19331200.0 24433.0 20112.8 29814.0 46114.0 34865.0 34322.0 23870.0 36294.0 28132.0 31072.0 True False 32202.185762029 26613.869272759268 29418.64687987846 35483.12975419788 30024.596563706797 32175.839914276043 25994.383757682743 30685.596253150186 29619.00008738371 29984.178737580718 1.0739725788009775 0.8875970726322656 0.9811389912442908 1.1833950852795925 1.0013479717580331 1.07309392049309 0.8669366596692089 1.0233929207035557 0.9878209553980776 1.0 14.871913837680957 TDESSPVLS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TDESSPVLSPR 11 0 Q8NA72;Q8NA72-3 Q8NA72 POC5 Centrosomal protein POC5 1 TDESSPVLS(0.999)PR;TDESSPVLS(1)PR 117.95 0.0011119 13441700.0 14850.400000000001 14264.9 21103.4 21686.0 31496.0 32684.0 28330.0 33391.0 33951.0 26403.0 True False 17364.27941123026 15681.024998560195 21606.585091090175 20471.003726960607 25324.584895927783 30969.99350310635 25646.377308561794 32514.521630688938 34447.46914601835 31189.654893967003 0.5567320148383246 0.502763658394738 0.6927484502327573 0.6563395393938873 0.8119546363055881 0.9929572356088127 0.8222719166258732 1.042477761976719 1.1044517569407768 1.0 14.928779969276043 -6.293581824395997 0.6160115639337553 1.049800604304709 0.48415631307307905 0.8738352952906381 0.07154282064640094 0.30821954504524274 0.2469615294641077 0.050552664253305186 0.09493721828780317 5.08648977265676e-07 6.293581824395997 -0.56564429123163 TDESSPVLS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 TDESSPVLSPR 11 0 Q8NA72;Q8NA72-3 Q8NA72 POC5 Centrosomal protein POC5 1 TDESSPVLS(1)PR 127.56 0.00035422 6856500.0 11407.0 10820.0 14770.0 12050.0 15578.0 18558.0 22582.0 18518.0 19402.0 16804.0 True False 11244.33408821239 10794.946954778818 13555.667613848766 12936.197197621615 14661.732667526381 17764.317600810944 23751.18546542539 19378.413883282632 17216.742447882436 19708.549010077462 0.570530792625215 0.5477291580044323 0.6878064745871155 0.65637491583003 0.743927554485593 0.9013508600621799 1.2051209580817355 0.9832491409374671 0.8735672240041159 1.0 14.266533945224511 -6.681042374791726 1.9980175417983914 1.0175348576400667 0.6144753552863698 0.8158257225669205 0.08617000255929769 0.14053087996226243 1.152537011989982 0.03573377786742261 0.03468394227737882 2.0842875059842802e-07 6.681042374791726 -0.4030595023536969 TDEVPAGGSRS(ph)EAEDEDDEDYVPYVPLR ddPTM_PC-9_AZD4547_30min_R2 4 TDEVPAGGSRSEAEDEDDEDYVPYVPLR 28 1 D6RD33;D6RGI7;A0A499FJW5;Q9UJV9 D6RD33 DDX41 Probable ATP-dependent RNA helicase DDX41 1 TDEVPAGGS(0.173)RS(0.827)EAEDEDDEDYVPYVPLR;T(0.012)DEVPAGGS(0.185)RS(0.803)EAEDEDDEDYVPYVPLR;T(0.003)DEVPAGGS(0.175)RS(0.821)EAEDEDDEDYVPYVPLR;TDEVPAGGS(0.193)RS(0.807)EAEDEDDEDYVPYVPLR 96.723 6.478400000000001e-10 18385200.0 20226.4 19923.699999999997 25933.0 40422.9 37186.0 32315.0 22630.6 30413.1 24841.0 26271.1 True False 26657.974464744533 26363.64639581131 25589.11147567881 31104.02493257939 32023.36577708307 30294.337941548565 24644.679558718704 25713.454218512186 26154.044546093395 25351.356785300486 1.0515403451779617 1.0399303918557046 1.009378381298952 1.2269175648466468 1.2631815349485052 1.194978959039943 0.9721246782739638 1.0142831579500178 1.0316625168266471 1.0 14.62977534078373 -7.26981158081133 24.930542752913343 1.0057078476826886 1.1316904280224034 0.3820524715951745 0.07878789911720464 780.972714901479 2325552.529606326 0.03807615858060393 0.026153618996592576 5.372648388168552e-08 7.26981158081133 0.12598258033971477 TDEVPAGGSRS(ph)EAEDEDDEDYVPYVPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TDEVPAGGSRSEAEDEDDEDYVPYVPLR 28 1 D6RD33;D6RGI7;A0A499FJW5;Q9UJV9 D6RD33 DDX41 Probable ATP-dependent RNA helicase DDX41 1 TDEVPAGGS(0.172)RS(0.828)EAEDEDDEDYVPYVPLR;T(0.004)DEVPAGGS(0.286)RS(0.705)EAEDEDDEDY(0.005)VPYVPLR;T(0.005)DEVPAGGS(0.172)RS(0.823)EAEDEDDEDYVPYVPLR 120.33 8.794e-13 12583900.0 32917.0 34187.9 40311.6 53457.6 51004.2 42772.0 40020.6 46642.1 42246.2 33638.0 True False 38489.19795961503 37581.848772040175 41272.78142659434 50462.54398387757 41010.293146713215 40528.96102419733 36229.55904394733 45417.79429638993 42863.97075304176 39736.3031217385 0.9686154708881003 0.9457812081033857 1.0386668659172593 1.2699355506041294 1.032061110996452 1.0199479528840516 0.9117496142746924 1.1429798629541676 1.0787105841658482 1.0 15.2781700368369 -5.348852165464393 5.188818619953786 1.0674934360859527 0.9577534472003368 0.18183852320154392 0.08929365537138509 0.35639366387569993 15.711796386442854 0.02482692644445637 0.05371903441409832 4.47865732442454e-06 5.348852165464393 -0.10973998888561587 TDEVPAGGSRS(ph)EAEDEDDEDYVPYVPLR ddPTM_PC-9_Lapatinib_30min_R1 4 TDEVPAGGSRSEAEDEDDEDYVPYVPLR 28 1 D6RD33;D6RGI7;A0A499FJW5;Q9UJV9 D6RD33 DDX41 Probable ATP-dependent RNA helicase DDX41 1 TDEVPAGGS(0.203)RS(0.797)EAEDEDDEDYVPYVPLR;TDEVPAGGS(0.186)RS(0.814)EAEDEDDEDYVPYVPLR;TDEVPAGGS(0.118)RS(0.882)EAEDEDDEDYVPYVPLR;T(0.006)DEVPAGGS(0.07)RS(0.925)EAEDEDDEDYVPYVPLR 104.57 1.6772e-10 15370600.0 26614.4 23846.899999999998 38115.5 28836.6 29698.4 33081.7 26991.1 27383.4 34907.7 26858.0 True False 26234.873775516782 23791.683968199177 34981.790720084835 30957.33976007763 27951.598501300916 31666.872808209228 28388.567089533422 28655.732732016517 30976.02723162283 31500.369513964568 0.8328433659765955 0.7552826946252799 1.1105200116645269 0.982761162416009 0.887341924319636 1.0052857568597995 0.901213780268462 0.9096951297448437 0.9833544085218019 1.0 14.943081131744146 -5.236099903273665 24.970447376872524 0.9652433784356964 0.7940629937957874 0.5531969975540094 0.06388542890188359 580.6365721851909 572178.4875204867 0.016412130568463926 0.04338651700406867 5.806308362853104e-06 5.236099903273665 -0.17118038463990903 TDGCHAYLSK ddPTM_PC-9_Lapatinib_30min_R1 1 TDGCHAYLSK 10 0 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 0 63.623999999999995 0.045612 3176100.0 57524.0 63945.0 72791.0 65641.0 62717.0 76866.0 62127.0 56681.0 76977.0 61011.0 False True 56703.697211390354 63796.93928126913 66806.40496138562 70468.45811195705 59028.109366366174 73578.6203633976 65343.63207025432 59314.60618416371 68307.03965625429 71556.67005795256 0.7924306310713868 0.891558246486331 0.9336153416205675 0.9847923059427697 0.8249141459288182 1.0282566293793085 0.9131731817220337 0.8289179210844467 0.9545866178643241 1.0 16.126798631631033 -4.787385525968825 2.6279419879062806 0.9277352867360994 0.7657991566936736 0.3108973605963494 0.06318632966742205 0.6003595797011488 5.501547989270845 0.015910999299663806 0.21694378954221888 1.6316029205628385e-05 4.787385525968825 -0.1619361300424258 TDGEPGPQGWS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDGEPGPQGWSPR 13 0 Q9H773 Q9H773 DCTPP1 dCTP pyrophosphatase 1 1 TDGEPGPQGWS(1)PR 125.33 0.00014282 15168000.0 18441.0 19973.0 25279.0 18506.0 23186.0 22933.0 26018.0 18902.0 20160.0 13944.0 True False 21562.69707364768 21955.78744304148 25881.74723114137 17469.168817261496 18642.86974209365 21730.353108760806 23553.386685992253 18405.842528324476 20454.80186102708 16471.936819356735 1.3090565675500052 1.332920814584505 1.5712631437929536 1.0605412714267384 1.1317958505150274 1.3192348505868918 1.4299099701690128 1.1174060907455121 1.2417970081690664 1.0 14.007722580964483 -14.522878745012235 0.11333810766980994 0.08208594346411982 1.4328815215379291 0.2958425103460399 0.14059817608130923 223.79752541086285 1.6663707258155744 47.22830178184899 1.7008019644763381 3.000000001851984e-15 14.522878745012235 1.3507955780738092 TDGFAEAIHS(ph)PQVAGVPR ddPTM_PC-9_AZD4547_30min_R2 7 TDGFAEAIHSPQVAGVPR 18 0 P12270 P12270 TPR Nucleoprotein TPR 1 TDGFAEAIHS(1)PQVAGVPR;TDGFAEAIHS(1)PQVAGVPR;TDGFAEAIHS(1)PQVAGVPR;TDGFAEAIHS(1)PQVAGVPR;TDGFAEAIHS(1)PQVAGVPR;TDGFAEAIHS(1)PQVAGVPR;T(0.029)DGFAEAIHS(0.971)PQVAGVPR 117.13 6.4142e-05 953199000.0 288244.9 332068.6 322677.0 464662.0 323371.0 326312.0 291628.6 379356.0 283855.5 338495.0 True False 379900.7823336255 439403.2809945994 318398.09214659367 357541.3548563362 278476.51843976625 305907.6590556278 317582.9804405433 320735.24693365407 298859.52222751157 326644.39307985967 1.1630408798743574 1.3452038066582452 0.9747545002823609 1.0945889855483382 0.8525372678651273 0.9365158733364144 0.972259090217719 0.9819095436156441 0.9149384730275927 1.0 18.31736135022269 -5.274439976850876 24.31934042570888 0.9650114775104849 1.2541223288355994 0.7226002247050509 0.0714205512225531 228.08561000550426 426664.88002627133 0.018347521158444513 0.038613984907589695 5.315694617992513e-06 5.274439976850876 0.2891108513251145 TDGFAEAIHS(ph)PQVAGVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TDGFAEAIHSPQVAGVPR 18 0 P12270 P12270 TPR Nucleoprotein TPR 1 TDGFAEAIHS(1)PQVAGVPR;TDGFAEAIHS(1)PQVAGVPR;TDGFAEAIHS(1)PQVAGVPR;TDGFAEAIHS(1)PQVAGVPR;T(0.004)DGFAEAIHS(0.996)PQVAGVPR 117.48 6.2091e-05 348385000.0 100713.4 110453.9 106855.0 118040.3 244502.0 268417.0 304176.0 310755.0 271523.0 261894.0 True False 117762.18943967827 121419.0332276055 109402.82844984389 111426.88468281596 196593.58827229313 254340.73999887708 275362.24723646586 302598.0105221391 275493.51020395145 309373.30904823635 0.38064754132140477 0.39246770705961026 0.35362723690163655 0.36016967664603117 0.6354574959200536 0.8221159762661401 0.8900646538759179 0.9780999254688746 0.89048894053429 1.0 18.238989209152734 -6.61473613131525 1.6093725307532971 0.9390505569826118 0.363109515640187 0.9787862048176746 0.03803758808273822 0.048258942616426236 0.2573194966604791 0.015597361001218116 0.015935955285914495 2.428084903073303e-07 6.61473613131525 -0.5759410413424247 down TDGFAEAIHS(ph)PQVAGVPR ddPTM_PC-9_Lapatinib_30min_R1 4 TDGFAEAIHSPQVAGVPR 18 0 P12270 P12270 TPR Nucleoprotein TPR 1 TDGFAEAIHS(1)PQVAGVPR;T(0.001)DGFAEAIHS(0.999)PQVAGVPR;TDGFAEAIHS(1)PQVAGVPR;TDGFAEAIHS(1)PQVAGVPR 143.14 0.0001115 460360000.0 54963.7 56004.3 58467.6 60518.8 172819.0 242405.0 268301.0 239081.0 279584.0 262928.0 True False 54179.90755889189 55874.625484243945 53660.619619462705 64969.554436798564 162654.12619522688 232037.90322365417 282192.31297312444 250189.57606810055 248094.30576996025 308374.75447046175 0.1756950164481821 0.18119066063041162 0.1740110655673102 0.21068376543457223 0.5274560379449188 0.7524542779842905 0.9150953795089434 0.8113166607873714 0.8045221023231472 1.0 18.234325136281583 -6.538956818538494 1.6915741744596573 0.8685488228245167 0.16922938934802095 0.9710357630629155 0.0549557456935991 0.054663660422831196 0.31798218344650225 0.021176394606962173 0.02288967728104404 2.890967314034599e-07 6.538956818538494 -0.6993194334764958 down TDGS(ph)ISGDR ddPTM_PC-9_Lapatinib_30min_R1 1 TDGSISGDR 9 0 P51116 P51116 FXR2 Fragile X mental retardation syndrome-related protein 2 1 T(0.001)DGS(0.997)IS(0.002)GDR 98.04 0.0045899999999999995 3578700.0 10933.0 14944.0 13282.0 11502.0 15730.0 16129.0 13045.0 16243.0 15730.0 13791.0 True False 10777.093415133351 14909.398086156616 12190.005230002667 12347.89544954721 14804.79232636988 15439.200268535373 13720.406270324793 16997.709077986812 13958.321755756662 16174.755974647598 0.6662909432467128 0.9217695840064412 0.753643841620198 0.7634053625848433 0.9153023606399375 0.9545244634747417 0.8482604802094222 1.0508788574386603 0.8629695420218403 1.0 13.981456326275953 -6.334599783211181 4.766832782867191 0.9395736670980274 0.7850847706636733 0.4936284285436162 0.08059526822022599 0.19559392806676026 8.388685411724252 0.02405585174499872 0.027641681244215306 4.628073172597605e-07 6.334599783211181 -0.15448889643435404 TDGS(ph)ISGDRQPVTVADYISR ddPTM_PC-9_AZD4547_30min_R2 1 TDGSISGDRQPVTVADYISR 20 1 P51116 P51116 FXR2 Fragile X mental retardation syndrome-related protein 2 1 T(0.105)DGS(0.489)IS(0.386)GDRQPVT(0.018)VADY(0.002)ISR 45.608000000000004 0.038438 56931000.0 52227.0 46608.0 59290.0 77309.0 66274.0 57880.0 49536.0 58349.0 58293.0 77811.0 True False 68834.09961091497 61673.12453088395 58503.77586060222 59486.60446214352 57072.999072511244 54260.754450157256 53944.60803605247 49332.50277663137 61374.24897248188 75086.86057382502 0.9167262965167872 0.821357079781585 0.7791479815976805 0.7922372037868942 0.7600930260814056 0.7226398072244392 0.7184293979505829 0.6570057983464085 0.8173766821977999 1.0 16.196272852622492 -4.15702731865077 0.9540941476478405 0.759421683475775 1.2682998738090547 0.15639762515026479 0.08690861786711897 8.403283117221585 2.620575543274422 0.026930707848477908 5.876779313208527 6.965826952304778e-05 4.15702731865077 0.5088781903332797 TDGS(ph)ISGDRQPVTVADYISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDGSISGDRQPVTVADYISR 20 1 P51116 P51116 FXR2 Fragile X mental retardation syndrome-related protein 2 1 T(0.126)DGS(0.458)IS(0.208)GDRQPVT(0.208)VADYISR 82.755 0.0049001 13845000.0 20935.0 24985.0 23102.0 26318.0 28654.0 36729.0 25002.0 24557.0 30769.0 19251.0 True False 24478.882014902334 27465.345679887447 23652.839294822894 24843.487784107234 23039.454394460085 34802.86658229082 22633.629561195274 23912.404770292247 31218.93841577093 22741.053909167855 1.0764180988566185 1.2077428684523295 1.0400942449411925 1.0924510307805833 1.0131216647427204 1.5303981390352517 0.995276193073476 1.0515082047561646 1.3728008622848078 1.0 14.473011495446155 TDGS(ph)ISGDRQPVTVADYISR ddPTM_PC-9_Lapatinib_30min_R1 1 TDGSISGDRQPVTVADYISR 20 1 P51116 P51116 FXR2 Fragile X mental retardation syndrome-related protein 2 1 T(0.08)DGS(0.744)IS(0.171)GDRQPVT(0.005)VADYISR 48.372 0.029814999999999998 46821000.0 69129.0 57161.0 59006.0 60232.0 62389.0 60534.0 57759.0 71596.0 76893.0 43709.0 True False 68143.20778329417 57028.64721646138 54154.75444974682 64661.66220806183 58719.40168149332 57945.10193164617 60749.478403042485 74922.61153404825 68232.50062081356 51264.042411418435 1.3292593517384441 1.112449282847795 1.0563886869304813 1.261345363463948 1.1454305770552011 1.130326427764105 1.1850309797167162 1.4615041656831995 1.3310011737508942 1.0 15.64565962596984 -7.554971367479032 24.99623895064371 1.302405240644893 1.1665236883881018 0.0684647221124206 0.1303311520716746 325.50763008109436 253527.1461623931 0.058418412912639515 0.03372818021133751 2.7863048603547485e-08 7.554971367479032 -0.1358815522567911 TDGSIS(ph)GDRQPVTVADYISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TDGSISGDRQPVTVADYISR 20 1 P51116 P51116 FXR2 Fragile X mental retardation syndrome-related protein 2 1 T(0.014)DGS(0.057)IS(0.877)GDRQPVT(0.051)VADYISR;T(0.001)DGS(0.103)IS(0.579)GDRQPVT(0.14)VADY(0.173)IS(0.005)R;T(0.061)DGS(0.235)IS(0.7)GDRQPVT(0.003)VADYISR 73.36 0.013900999999999998 34019500.0 93337.0 89206.0 83742.0 108771.0 133076.0 111403.0 117313.0 92210.0 117353.0 79111.0 True False 109137.11061021943 98061.78213808422 85738.72687330355 102676.91351033984 107000.71309405938 105560.83056622685 106200.2633674307 89789.58520457076 119069.06561493596 93453.1980576685 1.167826386667609 1.049314353881949 0.9174509664227384 1.098698767344265 1.1449657723648037 1.1295582469107897 1.1364005253399267 0.9607973517306815 1.2741037020633612 1.0 16.511956414766466 -5.970252473274634 24.999977566854547 1.1094499785654237 1.0391032647017926 0.0766542606942261 0.09749512096546126 495.6111839349915 416511.06234704284 0.02662809970843216 0.03949536814657975 1.0708965679493873e-06 5.970252473274634 -0.07034671386363112 TDGSIS(ph)GDRQPVTVADYISR ddPTM_PC-9_Lapatinib_30min_R1 1 TDGSISGDRQPVTVADYISR 20 1 P51116 P51116 FXR2 Fragile X mental retardation syndrome-related protein 2 1 T(0.005)DGS(0.021)IS(0.972)GDRQPVT(0.002)VADYISR 74.53699999999999 0.012034 10790000.0 37096.0 29312.0 39542.0 36227.0 35734.0 39768.0 32169.0 25608.0 44968.0 26727.0 True False 36567.00423742674 29244.129864923907 36291.00939653405 38891.254429729306 33632.19637574708 38067.21534373582 33834.55341587414 26797.841166600163 39903.23030596728 31346.726338511093 1.16653343135555 0.9329245277200116 1.1577288487681294 1.2406799360719645 1.0729093689897744 1.2143920527027492 1.079364813106708 0.854884841154134 1.2729632394481996 1.0 14.93602716414607 -10.681563113807009 6.0741251372892915 0.9999991963495525 1.1038243401901486 0.06228085861072041 0.12614768748121524 1.350141408460578e-06 1.8700142706382609e-07 0.11985276391560441 0.029068339338362108 2.0817898473113907e-11 10.681563113807009 0.10382514384059616 TDIT(ph)MKHKLGGGQY(ph)GEVY(ph)VGVWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDITMKHKLGGGQYGEVYVGVWK 23 2 P42684-2;P42684-6;P42684-3;P42684;P42684-4;P42684-7;P42684-10;P42684-5;P42684-8 P42684-2 ABL2 Abelson tyrosine-protein kinase 2 3 T(0.481)DIT(0.52)MKHKLGGGQY(1)GEVY(1)VGVWK 46.361999999999995 0.041195999999999997 0.0 1091.5 2588.1 969.46 2169.2 1020.5 898.27 2413.1 1219.4 1033.7 657.53 True False 1276.269391892329 2845.029463842972 992.5756030975239 2047.666756641287 820.5403507205457 851.1631398860409 2184.5136986689186 1187.3920420610975 1048.81590693173 776.7349839953841 1.6431207788883542 3.6628058764762406 1.277881933412983 2.6362489122203043 1.0563967989440035 1.0958218149359151 2.8124311942693447 1.5286964878977998 1.3502879727868196 1.0 9.601278635906464 -1.5228787458553459 0.12096350282346927 0.789068614499139 6.273245009140739 0.17609976997359156 0.7837648783293762 159.16753964681163 1.3266178069963026 5.221641098068484 147.19111753710035 0.02999999996027983 1.5228787458553459 5.4841763946416 TDLEKDIISDTSGDFR ddPTM_PC-9_AZD4547_30min_R2 3 TDLEKDIISDTSGDFR 16 1 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YN28;H0YNP5;H0YL33;H0YNA0;H0YN52 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ;; 80.102 0.010828 25726200.0 171541.0 186659.0 214986.0 252494.0 226549.0 238719.0 206482.0 261088.0 236377.0 233501.0 False True 226087.46972554392 246992.87143430923 212135.14517064317 194285.40929341305 195096.58187039229 223791.8631925896 224858.49799136337 220742.84880537988 248871.40564679 225326.20106217332 1.0033785181651402 1.0961569061653753 0.94145795815423 0.8622406465717881 0.8658406388192739 0.9931905927391003 0.9979243289568402 0.9796590354996986 1.1044938603394816 1.0 17.781655555185772 -7.8231958356596465 1.7156784578099968 1.045983099331834 0.9589662255926817 0.1793004541330261 0.06936188080147133 0.7264542173957246 4.028131354549991 0.06136213393639727 0.023136247702867634 1.502464309681518e-08 7.8231958356596465 -0.08701687373915223 TDLEKDIISDTSGDFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TDLEKDIISDTSGDFR 16 1 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YN28;H0YNP5;H0YL33;H0YNA0;H0YN52 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ; 123.68 4.9368999999999994e-05 17621300.0 171619.0 162323.0 171865.0 213231.0 253319.0 172660.0 201775.0 208530.0 164006.0 144236.0 False True 200670.70707024244 178437.35468466557 175962.91340164223 201284.35837422922 203682.96041565714 163605.40564944156 182661.41127550462 203056.30845579825 166404.2774811316 170384.8450284522 1.1777497408101811 1.0472607153228253 1.0327380546800307 1.181351301171282 1.1954288562556403 0.9602110188973758 1.0720519846997096 1.1917509941796192 0.976637784031462 1.0 17.378437494421803 -6.751320258277209 24.999984652502512 1.0541098845443424 1.1202742025543377 0.21947780254832538 0.07917666435620123 447.6735492328669 1106006.3458187552 0.02729093236691612 0.026995791908919486 1.7728816369257734e-07 6.751320258277209 0.06616431800999534 TDLEKDIISDTSGDFR ddPTM_PC-9_Lapatinib_30min_R1 3 TDLEKDIISDTSGDFR 16 1 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YN28;H0YNP5;H0YL33;H0YNA0;H0YN52 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ;; 135.86 1.1418e-05 32717400.0 124538.0 133740.0 139995.0 141202.0 153661.0 123624.0 130168.0 129599.0 132419.0 121520.0 False True 122762.06528252795 133430.3332469608 128485.15149632769 151586.466116064 144622.96208914963 118336.88970161934 136907.4621230845 135620.6426644099 117504.57778611188 142524.57008477836 0.8613396638172982 0.9361917960362343 0.9014947487292924 1.0635812900603405 1.0147230193581576 0.8302911535269225 0.9605884939112419 0.9515597386733967 0.8244513750591652 1.0 17.12085112412744 TDLEKDIISDTSGDFRK ddPTM_PC-9_AZD4547_30min_R2 1 TDLEKDIISDTSGDFRK 17 2 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YN28;H0YNP5;H0YL33;H0YNA0;H0YN52 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 91.07600000000001 0.0092255 23737000.0 31610.0 26275.0 31189.0 44091.0 48505.0 36055.0 36204.0 42004.0 36869.0 49677.0 False True 41661.322471155276 34767.87991437042 30775.413481469415 33926.50114915945 41770.91800724507 33800.47515031823 39426.085863558714 35513.24695589685 38817.820070444715 47937.82335050198 0.8690699652035624 0.7252703081690158 0.6419860421373752 0.7077188486657516 0.8713561669630472 0.7050899016249198 0.822442136667139 0.7408189290581333 0.8097534964536147 1.0 15.548876783473336 -10.511758861844093 0.38275724437995917 1.1043420250124174 0.7452735855425897 0.5047611191215341 0.07069132324571736 12.362884538973152 1.3174012439582674 1.479490503685992 0.05059215387965323 3.077805264447896e-11 10.511758861844093 -0.3590684394698277 TDLEKDIISDTSGDFRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDLEKDIISDTSGDFRK 17 2 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YN28;H0YNP5;H0YL33;H0YNA0;H0YN52 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 73.833 0.041030000000000004 7734800.0 31104.0 23041.0 21229.0 36487.0 43152.0 40269.0 43545.0 43371.0 34874.0 37072.0 False True 36369.292867997225 25328.358207335845 21735.179871430846 34442.75168245005 34696.67536922391 38157.22275047696 39420.10236150099 42232.557205373 35383.96627487391 43792.86013820945 0.830484529971699 0.5783672983997853 0.49631788841457314 0.7864924002165962 0.7922906898458298 0.8713115021502016 0.9001490708095311 0.9643708374398895 0.8079848213430858 1.0 15.418408055703619 -6.32490215929528 1.578033756054378 0.9080847322306712 0.6360562328452087 0.5770479294054413 0.09747291627402697 0.273813866198145 1.3593911357831974 0.036606489350746084 0.04717490604146387 4.732578655834454e-07 6.32490215929528 -0.2720284993854625 TDLLLEPYNK ddPTM_PC-9_Lapatinib_30min_R1 1 TDLLLEPYNK 10 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 92.051 0.035383 6533000.0 56213.0 64776.0 71668.0 62151.0 71101.0 55918.0 71016.0 68620.0 60277.0 74872.0 False True 55411.39231179833 64626.01515182556 65775.73368648023 66721.79186965806 66918.97896994429 53526.5174912246 74692.86099604331 71808.3357096261 53487.96951505048 87813.52543933118 0.6310120455200388 0.7359460268620526 0.7490387540803556 0.7598122445927191 0.762057765419946 0.609547529534105 0.8505849255266182 0.8177366225802791 0.6091085541486929 1.0 16.422155546888952 -11.6870441452304 2.3577658099559393 1.6555016034277792 0.7311546250348746 0.5157518264193057 0.07974407477724765 8521494.933435632 2303586.0777950217 29760805.830580167 0.01946882665238247 2.055681629130322e-12 11.6870441452304 -0.9243469783929046 TDLQGSAS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDLQGSASPSK 11 0 Q6VY07-2;Q6VY07;B4DF77 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 T(0.005)DLQGS(0.052)AS(0.901)PS(0.041)K 114.7 0.0014317 5425300.0 23102.0 34161.0 34646.0 31193.0 30254.0 22167.0 32425.0 20352.0 20335.0 19241.0 True False 27012.712314701395 37552.27831781609 35472.092035686685 29445.35733907048 24325.9458801562 21004.523497226735 29353.4692633292 19817.781564726458 20632.36090495959 22729.24098832781 1.188456417377654 1.6521571634134367 1.5606368929742414 1.2954835295288396 1.0702489314380692 0.9241190019505372 1.2914408043103218 0.8719068786724344 0.9077452659134094 1.0 14.472261887697352 -6.131412687257807 2.5921386318450907 1.0091985465657576 1.4829760454178156 0.6400974364955214 0.15557055941120845 0.17812628397646335 2.3323923185792563 0.049446102886489325 0.0682274796375823 7.389028007890736e-07 6.131412687257807 0.473777498852058 TDLQGSAS(ph)PSKVEGVHTPR ddPTM_PC-9_AZD4547_30min_R2 1 TDLQGSASPSKVEGVHTPR 19 1 Q6VY07-2;Q6VY07;B4DF77 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 T(0.002)DLQGS(0.225)AS(0.725)PS(0.049)KVEGVHTPR 68.525 0.0035335 41875000.0 149480.0 116180.0 239700.0 330700.0 316420.0 258030.0 222720.0 270470.0 227780.0 270620.0 True False 197011.5306228502 153732.91297627232 236521.42138280204 254462.22426406806 272490.54480677214 241895.34330984898 242541.64853419003 228675.07628229234 239819.98577791365 261145.67617031763 0.7544123782250963 0.5886864191310931 0.9057068255977717 0.9744071891050929 1.0434426822715435 0.9262850791069054 0.9287599629871177 0.8756609706727514 0.9183379533402825 1.0 17.99449529141797 -5.361129859074999 5.3332596495136615 0.9479375682973525 0.6733371984771461 0.7830015842843437 0.05818090779894837 0.09177908339668547 3.88454148375124 0.01573367083256615 0.033788890077761605 4.353816700635062e-06 5.361129859074999 -0.2746003698202064 TDLQGSAS(ph)PSKVEGVHTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TDLQGSASPSKVEGVHTPR 19 1 Q6VY07-2;Q6VY07;B4DF77 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 T(0.004)DLQGS(0.276)AS(0.526)PS(0.194)KVEGVHTPR;T(0.002)DLQGS(0.225)AS(0.635)PS(0.138)KVEGVHTPR 75.91 0.0016394000000000003 84041000.0 262580.0 301040.0 314520.0 433860.0 474190.0 435960.0 416400.0 444870.0 389350.0 320400.0 True False 307029.6078086009 330925.2616959505 322019.34962374164 409552.23079309805 381275.8735013968 413097.4901362826 376955.57752506627 433192.6338787274 395043.507172167 378485.9837149963 0.8112046971858202 0.8743395421087522 0.8508091804694817 1.0820803105393064 1.0073711838917165 1.0914472606926153 0.9959565049809547 1.1445407558471854 1.0437467282002144 1.0 18.529880349022235 -5.756548555552242 24.95529696281851 1.0556143386403969 0.848339913595559 0.809628889663448 0.04590611893685705 45.46952659458623 232003.40640447856 0.011923191994061697 0.019835361731629544 1.7516665811721468e-06 5.756548555552242 -0.20727442504483784 TDLQGSAS(ph)PSKVEGVHTPR ddPTM_PC-9_Lapatinib_30min_R1 2 TDLQGSASPSKVEGVHTPR 19 1 Q6VY07-2;Q6VY07;B4DF77 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 T(0.004)DLQGS(0.234)AS(0.6)PS(0.161)KVEGVHT(0.001)PR;T(0.001)DLQGS(0.226)AS(0.74)PS(0.033)KVEGVHTPR 70.334 0.0029912 76200000.0 565170.0 473320.0 595250.0 530880.0 600940.0 597700.0 433590.0 481230.0 588350.0 427820.0 True False 557110.5721605145 472224.0566206941 546310.8427314475 569922.6861637653 565593.8906934982 572137.7643067522 456039.1686278365 503589.7026164858 522083.8273998369 501768.1169656836 1.1102948818858809 0.941120092437021 1.08877153461867 1.1358288159284198 1.1272017323734815 1.1402433613490857 0.908864380195415 1.0036303335927717 1.0404882449626482 1.0 18.936661277274695 -7.251753475557918 24.991323999367726 0.9885482652178124 1.0874228819320904 0.39719242823511036 0.06168537096888758 792.8540389287226 2045704.0156815362 0.025582450884166517 0.019555040879066336 5.600754344615702e-08 7.251753475557918 0.098874616714278 TDLQGSASPS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDLQGSASPSK 11 0 Q6VY07-2;Q6VY07;B4DF77 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 T(0.002)DLQGS(0.133)AS(0.336)PS(0.529)K 91.441 0.008190600000000001 5695300.0 25039.0 47014.0 30682.0 28828.0 28944.0 21059.0 30855.0 20455.0 19079.0 20074.0 True False 29277.608157207505 51681.239215298265 31413.575242132953 27212.860621637024 23272.630976242497 19954.628967749257 27932.191029144877 19918.077923863988 19357.994281078154 23713.257294303425 1.2346514776036606 2.1794238798106202 1.3247262850590904 1.1475800344043963 0.9814185663069249 0.8414967509563904 1.1779145598801797 0.8399553750318755 0.8163363658070069 1.0 14.533406227083528 -5.665683836442844 2.4550675371225577 0.9544442798034494 1.713751291905451 0.5923208320664533 0.24326318478361755 0.1737341582342067 2.115906136531557 0.06661322678093948 0.1333798815373131 2.15931580495706e-06 5.665683836442844 0.7593070121020016 TDLQGSASPS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 TDLQGSASPSK 11 0 Q6VY07-2;Q6VY07;B4DF77 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 T(0.024)DLQGS(0.001)AS(0.321)PS(0.653)K 104.7 0.0026506 6171100.0 38836.0 40258.0 34478.0 29735.0 40985.0 44693.0 36320.0 35165.0 33676.0 33110.0 True False 38282.191518349835 40164.785074444124 31643.35192892876 31921.811093052194 38574.34287961026 42781.584574471555 38200.47188487515 36798.894276143976 29883.05425599881 38833.0193836982 0.9858154767749119 1.034294672726504 0.814856852007042 0.8220275322307985 0.9933387486166855 1.1016806123613179 0.9837110915179419 0.947618672463874 0.7695269317261352 1.0 15.244996265022355 -11.804837032246846 2.3496417115422847 1.263058219239605 0.9428276526910356 0.030876232183930874 0.10034767079939662 38381304.830048 7276539.137649373 53445073.371606685 0.02657413605759634 1.5673390992546987e-12 11.804837032246846 -0.3202305665485693 TDLQGSASPS(ph)KVEGVHTPR ddPTM_PC-9_AZD4547_30min_R2 2 TDLQGSASPSKVEGVHTPR 19 1 Q6VY07-2;Q6VY07;B4DF77 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 T(0.001)DLQGS(0.098)AS(0.169)PS(0.731)KVEGVHTPR;TDLQGSAS(0.004)PS(0.679)KVEGVHT(0.317)PR 71.637 0.0026009 60247800.0 279548.0 201523.0 406689.0 564911.0 522338.0 488277.0 355969.0 468069.0 375093.0 517938.0 True False 368438.4490403832 266661.3687529463 401296.0381341278 434679.4967379463 449820.3849101809 457744.9620017191 387649.5513966731 395739.69120559085 394919.6502124637 499805.1482680579 0.7371641735126356 0.5335306562507219 0.8029049711166696 0.8696979177669792 0.8999914996252321 0.9158468326865236 0.7756013573288905 0.7917879449159771 0.7901472235349174 1.0 18.931006236490767 -5.4284282737495735 5.514975785724895 0.8535320519619415 0.6373570858995644 0.5611267646265172 0.07912011751697816 0.15792538919573063 7.254732402882543 0.02061021039006203 0.0436209542107418 3.728822635244638e-06 5.4284282737495735 -0.21617496606237707 TDLQGSASPS(ph)KVEGVHTPR ddPTM_PC-9_Lapatinib_30min_R1 1 TDLQGSASPSKVEGVHTPR 19 1 Q6VY07-2;Q6VY07;B4DF77 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 TDLQGSAS(0.005)PS(0.717)KVEGVHT(0.277)PR 48.677 0.029867 6289200.0 81085.0 38174.0 63804.0 52254.0 45266.0 41146.0 39134.0 36295.0 49227.0 35912.0 True False 79928.71303083216 38085.61044840358 58558.28141056245 56096.93347423405 42603.5428763801 39386.28149601069 41160.16703586738 37981.39820141176 43682.536876709026 42119.34135026787 1.897672434289475 0.9042309121522236 1.3902943287642373 1.3318568542591251 1.011495942495529 0.9351115243819027 0.9772272242715309 0.9017566985569732 1.0371134845970524 1.0 15.362195255653537 TDMDQIIT(ph)SK ddPTM_PC-9_AZD4547_30min_R2 1 TDMDQIITSK 10 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 1 TDMDQIIT(0.5)S(0.5)K 95.48299999999999 0.010269 0.0 8004.9 10089.0 9107.1 14699.0 9626.0 10036.0 10034.0 9771.2 9685.4 9796.8 True False 10550.291687736504 13350.07194885189 8986.333903526567 11310.37264728618 8289.596056854778 9408.447333479236 10927.006561566344 8261.285559838565 10197.350470864008 9453.817013913844 1.1159822188443993 1.4121356410012649 0.950550861128447 1.1963815917570557 0.8768517567723597 0.9952009140469047 1.1558301314150998 0.873857146555709 1.0786490214329147 1.0 13.206681225128278 -5.273351341113985 24.998179227676303 1.017145917665955 1.264058938213511 0.405504739881582 0.12017462918898676 599.3017469234657 1257682.2168448954 0.02957026126513039 0.06231590978065668 5.329036058696091e-06 5.273351341113985 0.24691302054755604 TDNSSLS(ph)SPLNPK ddPTM_PC-9_AZD4547_30min_R2 2 TDNSSLSSPLNPK 13 0 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 TDNSS(0.009)LS(0.767)S(0.224)PLNPK;TDNS(0.001)S(0.019)LS(0.773)S(0.207)PLNPK 175.6 5.3018e-05 36061000.0 126389.0 167763.0 171979.0 197850.0 172383.0 171492.0 123443.0 190028.0 142302.0 164332.0 True False 166578.07294548678 221989.10896572904 169698.4460909174 152238.73925202864 148450.59599717392 160768.57813003406 134429.18785922203 160663.5390090268 149823.79320470936 158578.78669876812 1.050443608588795 1.3998663603563408 1.070120724364425 0.9600195740002547 0.9361314907722593 1.0138088547456579 0.847712299089411 1.0131464766105118 0.9447908911632077 1.0 17.274840267096685 -5.509001467189931 5.091422021612577 0.9593596116062444 1.2299274966897265 0.5762321861939608 0.09068516613444051 0.1076952479076413 8.158933951405638 0.022595969518400125 0.044594295305151334 3.097408835130758e-06 5.509001467189931 0.27056788508348206 TDNSSLS(ph)SPLNPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDNSSLSSPLNPK 13 0 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 TDNSS(0.001)LS(0.771)S(0.227)PLNPK 147.7 0.00011129 13259000.0 47336.0 48089.0 32403.0 42228.0 53737.0 41520.0 50167.0 41197.0 33593.0 28541.0 True False 55349.04987138364 52862.9581108708 33175.61040906183 39862.10206502319 43207.62060428216 39342.61810821735 45414.818582372696 40115.622401829605 34084.23407328781 33715.25736956831 1.6416617931958066 1.5679239084968508 0.9839939836557924 1.1823164102850088 1.2815450325846167 1.1669084318996878 1.3470108824785219 1.1898358645791718 1.0109439088563072 1.0 15.041113990247702 -5.171516696752017 6.322790152955239 1.1668046995384223 1.6175847653998394 0.7146602087015408 0.11565262764529237 0.12706474763739853 7.345034868592142 0.029715129618207086 0.08089462732008616 6.7372599311044556e-06 5.171516696752017 0.45078006586141717 TDNSSLS(ph)SPLNPK ddPTM_PC-9_Lapatinib_30min_R1 2 TDNSSLSSPLNPK 13 0 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 TDNSS(0.007)LS(0.496)S(0.496)PLNPK;TDNS(0.003)S(0.011)LS(0.78)S(0.206)PLNPK 165.78 0.00021988 32292000.0 192010.0 221900.0 206317.0 156500.0 151765.0 185678.0 183666.0 148174.0 164726.0 119163.0 True False 189271.90218967822 221386.20418349517 189354.41266665113 168009.53206869564 142838.48108147012 177736.98477655853 193175.32679535996 155058.70497578185 146172.82323832004 139760.16577528353 1.3542621471557441 1.5840436576145442 1.354852519072629 1.2021274526737002 1.022025698732614 1.271728491380991 1.3821915974682026 1.109462800903488 1.0458832989175701 1.0 17.09259369904509 -1.5228787486619844 0.1688234746935496 0.984026327852103 3.032894291404586 0.5140737230332599 0.1259713027299881 53.6960438107978 0.5783106021525765 0.3632515483749775 27.728703259395264 0.029999999766404117 1.5228787486619844 2.048867963552483 TDNSSLSS(ph)PLNPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TDNSSLSSPLNPK 13 0 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 TDNS(0.001)S(0.01)LS(0.444)S(0.546)PLNPK;TDNSS(0.001)LS(0.086)S(0.913)PLNPK 174.46 7.2653e-05 14901800.0 132072.0 130698.0 106016.0 137759.0 151985.0 121246.0 143150.0 112167.0 99690.0 75787.0 True False 154429.1810590961 143672.8336870095 108543.8235079188 130040.80985070422 122204.63028345145 114887.64631861557 129589.79568374925 109222.73510076043 101147.77765504929 89526.5831704381 1.7249533668128305 1.6048064005021765 1.2124200395459774 1.4525385114177352 1.3650094302247842 1.2832796947013585 1.4475007432936424 1.2200033915381912 1.129807193272272 1.0 16.450028505655368 -1.5228787452803387 0.126332154989704 0.9131981680907049 3.2850044138694856 0.7109348094425535 0.11235036264029415 53.24890967001161 0.4596277673257038 0.7019388178231282 22.38193326509299 0.02999999999999992 1.5228787452803387 2.3718062457787807 TDPPAVNGASLGPSIS(ph)EPDLTSVK ddPTM_PC-9_AZD4547_30min_R2 1 TDPPAVNGASLGPSISEPDLTSVK 24 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 TDPPAVNGASLGPS(0.226)IS(0.598)EPDLT(0.13)S(0.046)VK 104.29 9.7634e-07 1827500.0 7766.4 10212.0 11863.0 12863.0 13283.0 10766.0 11856.0 14927.0 12591.0 13897.0 True False 10235.953648844677 13512.82929345579 11705.68886885349 9897.634081368937 11438.884731269678 10092.800318078664 12911.161031884654 12620.375138336158 13256.534554964048 13410.470259917589 0.763280738889434 1.0076327698845984 0.8728768374245978 0.7380527222040728 0.8529816262640124 0.7526059953501352 0.9627672096238628 0.9410837124822581 0.9885212299069304 1.0 13.711072208123348 -7.350485188589909 8.782047008912745 0.9688637428647161 0.8379814648978976 0.4647920592930962 0.07431710746943057 0.38584564159158774 35.26267131337025 0.03224965288787171 0.02169894763633361 4.46184841246717e-08 7.350485188589909 -0.1308822779668185 TDPTTLTDEEINR ddPTM_PC-9_Lapatinib_30min_R1 2 TDPTTLTDEEINR 13 0 V9GZ78;V9GYY3;A0A384N5Y3;F5H2F4;P11586;A0A494C1T2 V9GZ78 MTHFD1 C-1-tetrahydrofolate synthase, cytoplasmic;Methylenetetrahydrofolate dehydrogenase;Methenyltetrahydrofolate cyclohydrolase;Formyltetrahydrofolate synthetase;C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed 0 ; 129.82 0.00040579 6975900.0 15205.6 18180.6 20094.4 15862.7 20967.8 19330.6 21313.0 21838.0 20720.4 18731.5 False True 14988.765355634463 18138.503937712743 18442.315998627124 17029.295874415962 19734.5152282809 18503.875299829506 22416.482854690094 22852.673203538525 18386.65035651496 21969.21481684516 0.6822622237796886 0.8256327815505189 0.8394617719558305 0.7751435823440783 0.898280407051654 0.8422638430228028 1.0203588540407 1.040213471171303 0.8369279698797781 1.0 14.423195688086865 -6.6101143358206125 0.9427834013258651 0.9763082381615518 0.7724033882630066 0.5719747257367673 0.07104444767639795 0.4170748271245565 0.8072246952911025 0.03949471472497603 0.042596176269504474 2.4540627545463785e-07 6.6101143358206125 -0.20390484989854518 TDQDEEHCR ddPTM_PC-9_AZD4547_30min_R2 2 TDQDEEHCR 9 0 Q16186;A0A087WX59;A0A087WUX6 Q16186 ADRM1 Proteasomal ubiquitin receptor ADRM1 0 ; 183.72 0.00025158 5612100.0 56847.0 43774.0 38208.0 24814.0 27092.0 20089.0 20280.1 22463.8 48214.0 72407.0 False True 74923.16350894544 57923.08945277454 37701.33695533631 19093.51567247835 23330.743441960265 18832.831654271075 22084.98961224055 18992.53587677066 50762.49360916815 69872.05296897553 1.072290856291466 0.8289879428402289 0.5395767743088412 0.27326398554449544 0.3339066543861183 0.26953310879005077 0.3160775828648786 0.2718187754581033 0.7265063992281381 1.0 16.092427909466558 -5.148586452169752 2.076191213579663 0.40663981412232153 1.0721741063384473 0.42300534760676123 0.2299836302185283 0.31914035068382124 2.3754694254212674 0.06034553960958715 0.2973464462521129 7.102537703443585e-06 5.148586452169752 0.6655342922161258 TDQDEEHCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TDQDEEHCR 9 0 Q16186;A0A087WX59;A0A087WUX6 Q16186 ADRM1 Proteasomal ubiquitin receptor ADRM1 0 ; 159.34 0.0001063 4258600.0 7339.3 23539.0 17392.6 9896.1 43317.0 41283.0 12471.8 33594.0 36215.0 47099.0 False True 8581.698532217466 25875.7963561685 17807.305545802818 9341.653600589085 34829.34480368633 39118.046805432 11290.380815987319 32712.193095785206 36744.57586295115 55637.675864521116 0.15424257751373507 0.46507687379279816 0.3200584005191729 0.16790157847959364 0.6260028705817349 0.7030855656279613 0.20292689513989814 0.5879503877092218 0.6604261463477544 1.0 15.763774535433177 -13.665328185920288 0.10005012380233022 2.6290553990783843 6.148174290635406e-12 0.5898564193918663 0.16834994813827275 113.34056091436085 0.9241506158804019 40.29992607278174 3.1138018555504536 2.1610848265776602e-14 13.665328185920288 -2.6290553990722363 TDQDEEHCR ddPTM_PC-9_Lapatinib_30min_R1 2 TDQDEEHCR 9 0 Q16186;A0A087WX59;A0A087WUX6 Q16186 ADRM1 Proteasomal ubiquitin receptor ADRM1 0 ; 194.12 0.00058003 10029800.0 11595.4 41524.0 17806.2 34384.0 40700.0 15144.8 68718.0 71398.0 39871.0 42615.0 False True 11430.047469664061 41427.85372922695 16342.242969919693 36912.71406166156 38306.10601927869 14497.092208253129 72275.88180024372 74715.41173121348 35380.30811975677 49980.94596908184 0.2286880979950775 0.82887294199782 0.32696946112282443 0.7385357228831908 0.7664141859774884 0.2900523775044397 1.4460687047610803 1.4948779036201585 0.7078759201885253 1.0 15.609090586536054 -7.26260926553807 24.999440767804895 1.2034454654847908 0.554517754717889 0.5386969644192368 0.285078398205923 80.54651022269007 1721179.0852055661 0.11116794375053544 0.07971214439349615 5.46249100033252e-08 7.26260926553807 -0.6489277107669018 TDQEAPNASQPT(ph)PPPLPK ddPTM_PC-9_AZD4547_30min_R2 2 TDQEAPNASQPTPPPLPK 18 0 Q9H792 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 TDQEAPNAS(0.002)QPT(0.998)PPPLPK;TDQEAPNAS(0.001)QPT(0.999)PPPLPK 179.87 2.3938000000000002e-08 10297100.0 48687.0 60101.0 77814.0 103182.0 107696.0 100049.0 80502.0 100921.0 85728.0 86888.0 True False 64168.4532474893 79527.47291088781 76782.13551723564 79394.98404600864 92744.26936827679 93792.92021395615 87666.52204696165 85325.97838386957 90259.40706281927 83846.07756664875 0.7653125239696774 0.9484936590822856 0.915751073223455 0.9469135152195766 1.1061253198702696 1.1186321761969213 1.0455649756218597 1.017650209290285 1.0764893204583434 1.0 16.355455673684844 -4.758302285849617 0.6983819432876578 1.0610603538070726 0.6176621071059959 0.7353976705305107 0.05166349687341499 1.720249980687271 0.6211951855442166 0.023824137856515132 0.6115957791079444 1.7446074156062854e-05 4.758302285849617 -0.44339824670107675 TDQEAPNASQPT(ph)PPPLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDQEAPNASQPTPPPLPK 18 0 Q9H792 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 TDQEAPNAS(0.061)QPT(0.939)PPPLPK 134.06 2.5225e-06 0.0 18693.0 16454.0 18204.0 22301.0 29209.0 24523.0 22287.0 20625.0 16249.0 20695.0 True False 21857.35569642078 18087.444379302287 18638.052399054443 21051.547270817497 23485.70612856093 23236.970709725778 20175.814016093067 20083.61560399388 16486.610884912152 24446.839678470136 0.894076943436993 0.7398684090537704 0.7623910756640098 0.8611152831078281 0.9606847526080986 0.9505102097180329 0.8252933418572512 0.8215219581810052 0.674386182498329 1.0 14.57736035495645 -4.468575358466793 22.293974519721992 0.8412580984133701 1.7519697061993278 0.022155098252403027 0.09837812259380253 484.51129062511734 673135.714387788 0.02459397154201064 93544.02177171365 3.399575115024972e-05 4.468575358466793 0.9107116077859577 TDQEAPNASQPT(ph)PPPLPK ddPTM_PC-9_Lapatinib_30min_R1 2 TDQEAPNASQPTPPPLPK 18 0 Q9H792 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 TDQEAPNAS(0.018)QPT(0.982)PPPLPK;TDQEAPNAS(0.008)QPT(0.992)PPPLPK 147.1 0.00011177 11512200.0 46639.0 68374.0 62713.0 58993.0 70769.0 63147.0 51133.0 55862.0 60594.0 33763.0 True False 45973.91930745492 68215.6842038861 57556.97921918065 63331.54201487899 66606.50655720719 60446.35001284666 53780.4165443095 58457.552454257224 53769.26563689253 39598.889563630386 1.160990113967228 1.722666593826379 1.4534998292488452 1.5993262112341118 1.6820296551543192 1.5264657842416782 1.358129410621255 1.4762422153359467 1.357847814153782 1.0 15.273172354210256 -8.922367028733602 0.7276592462122679 0.9948661764323854 1.5311133966985895 0.5010888233340718 0.15105357128079108 1.08725300558833 1.03919352728232 0.15428543965907965 0.053344746998068 1.195729575311095e-09 8.922367028733602 0.5362472202662041 TDQGILVTNQDACALASSVSS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 2 TDQGILVTNQDACALASSVSSPVK 24 0 Q8IWI9-3;Q8IWI9;H3BP52;H3BTF4 Q8IWI9-3 MGA MAX gene-associated protein 1 TDQGILVTNQDACALAS(0.001)S(0.003)VS(0.256)S(0.74)PVK;TDQGILVTNQDACALAS(0.003)S(0.003)VS(0.261)S(0.733)PVK 152.0 1.2306e-08 11945700.0 140296.0 126035.0 162524.0 179358.0 187350.0 175791.0 167357.0 181957.0 166592.0 184871.0 True False 184907.20966191744 166773.34900124365 160368.82556870504 138009.7841534768 161339.6863963996 164798.76098043518 182251.44878653184 153839.7266058973 175397.71301569117 178398.7225603529 1.036482812254234 0.9348348833878205 0.8989348312987595 0.7736029842186095 0.9043769152652863 0.9237664856298687 1.0215961536657054 0.8623364808784031 0.9831780771656228 1.0 17.444745759188066 -7.011021625349636 21.408950400281917 0.9577879446745831 0.9040106102937938 0.11866387563384717 0.07151227354804776 197.73891594853285 384098.73185724387 0.027563128283029457 0.022725297545321547 9.749410900895648e-08 7.011021625349636 -0.05377733438078924 TDQGILVTNQDACALASSVSS(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDQGILVTNQDACALASSVSSPVK 24 0 Q8IWI9-3;Q8IWI9;H3BP52;H3BTF4 Q8IWI9-3 MGA MAX gene-associated protein 1 TDQGILVTNQDACALASS(0.001)VS(0.067)S(0.932)PVK 132.7 3.8655000000000003e-07 3949400.0 63799.0 65552.0 62965.0 74105.0 81710.0 69562.0 74638.0 76879.0 67709.0 61238.0 True False 74598.91061231207 72059.56934192436 64466.32439609223 69953.13710165156 65699.512060143 65914.0462630976 67567.74830767495 74861.00771003366 68699.1160321569 72339.96464025874 1.0312268050349058 0.9961239226514864 0.8911578090572543 0.9670054091057869 0.9082049236111986 0.9111705623700985 0.9340307068670041 1.034849935057501 0.9496703015240953 1.0 16.14250527235464 -7.7375181478094746 24.99734346343772 0.9941951267297726 0.9457854944675531 0.18524565313116914 0.04436923212787417 377.3654532549575 394342.1142080732 0.021761428631480475 0.012555464598624414 1.8301296293141088e-08 7.7375181478094746 -0.048409632262219504 TDQGILVTNQDACALASSVSS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 2 TDQGILVTNQDACALASSVSSPVK 24 0 Q8IWI9-3;Q8IWI9;H3BP52;H3BTF4 Q8IWI9-3 MGA MAX gene-associated protein 1 TDQGILVTNQDACALASSVS(0.271)S(0.728)PVK;TDQGILVTNQDACALASSVS(0.248)S(0.751)PVK 195.25 5.2881e-25 15444900.0 110879.0 134981.0 157577.0 146962.0 151810.0 151867.0 139006.0 138458.0 149571.0 134010.0 True False 109297.84512728144 134668.4597877077 144621.62732481005 157770.07573086026 142880.8342699436 145372.00242926792 146203.0505184182 144891.26414577998 132724.73892754468 157173.44994289905 0.695396360943844 0.8568143018851632 0.9201403123577865 1.003795970554683 0.9090646945896527 0.9249144972136287 0.9302019556835688 0.9218558490535063 0.8444475767107195 1.0 17.261998009649766 -4.778093725694174 2.124309309562821 0.930381230124559 0.6293939213112437 0.7388517257316177 0.042780381723053026 0.3488521125545813 1.7749762975768175 0.011331665188453828 0.20491447402929697 1.666887440441779e-05 4.778093725694174 -0.30098730881331526 TDRGSHS(ph)DLWS(ph)SS(ph)S(ph)SLESSS(ph)FPLPK ddPTM_PC-9_Lapatinib_30min_R1 1 TDRGSHSDLWSSSSSLESSSFPLPK 25 1 H0YBE8;H3BLZ3;Q8IX03;Q8IX03-2 H0YBE8 WWC1 Protein KIBRA 5 T(0.402)DRGS(0.482)HS(0.503)DLWS(0.509)S(0.157)S(0.861)S(0.851)S(0.223)LES(0.092)S(0.448)S(0.471)FPLPK 48.696999999999996 0.035383 0.0 4330.7 2788.1 3531.0 2757.1 3580.3 4312.0 2532.5 1286.9 2516.4 2571.8 True False 4268.943423846883 2781.644325750353 3240.6948100541654 2959.8663314159808 3369.7137931406287 4127.585811762947 2663.6204583823323 1346.6940720594241 2232.976533133253 3016.3322032919086 1.4152762813021467 0.9221942870598184 1.0743825917176484 0.981279955896667 1.117156057765472 1.368412208462403 0.8830660149022577 0.4464674251031415 0.740295293302332 1.0 11.558579613019585 -7.51906514927903 24.75457037934843 0.6889820884258586 1.1242748193217662 0.49204200927922714 0.19138637556503935 112.33190959606561 729179.1835889076 0.0851830795510274 0.05061196799781216 3.0264593895508913e-08 7.51906514927903 0.4352927308959076 TDRLEVCR ddPTM_PC-9_Lapatinib_30min_R1 1 TDRLEVCR 8 1 C9JP00;A0A0A0MQX8;Q9NR56-7;Q9NR56-6;Q9NR56-2;Q9NR56-5;Q9NR56;C9JCX1;H7C4Y1;H7C4T5;Q86VM6 C9JP00 MBNL1 Muscleblind-like protein 1 0 87.696 0.014948 1874700.0 13801.0 11946.0 13669.0 11637.0 13216.0 12321.0 11757.0 13224.0 10788.0 12447.0 False True 13604.19520920657 11918.339770960047 12545.187583865865 12492.823799894008 12438.66086365572 11794.059551653821 12365.719932557182 13838.435316585466 9572.94183732377 14598.447365415028 0.93189329444966 0.8164114629885652 0.8593508110723124 0.8557638690735412 0.8520536843612542 0.8078982138603972 0.8470571988259952 0.9479388437821069 0.655750683459865 1.0 13.8335273173308 -4.74814092275312 24.36836738209918 0.8467730309712311 0.9318935811419438 0.07737166660527584 0.08538304557966102 1245.229271023113 2281597.2634384604 0.01932121420535829 0.3537580857497058 1.7859079775591524e-05 4.74814092275312 0.08512055017071263 TDS(ph)ASADPDNLK ddPTM_PC-9_AZD4547_30min_R2 1 TDSASADPDNLK 12 0 Q96Q15;H3BR09;E9PNP6;I3L0W2 Q96Q15 SMG1 Serine/threonine-protein kinase SMG1 1 T(0.114)DS(0.857)AS(0.029)ADPDNLK 92.23899999999999 0.005969100000000001 3185800.0 18853.0 14645.0 19085.0 21539.0 19196.0 18602.0 20342.0 26331.0 22453.0 21548.0 True False 24847.861833239185 19378.70985141599 18831.920430082526 16573.516324232725 16530.966747079183 17438.813999340444 22152.39859232436 22262.148976186058 23639.81974129201 20793.611078700753 1.1949757903614573 0.931955001854677 0.9056589718258403 0.7970484905918654 0.7950022093089993 0.8386621223863957 1.0653463945478636 1.0706244765244048 1.1368789986413987 1.0 14.343852702100861 -7.279300483731709 21.171277897692143 1.0740980734421586 0.9008896843806279 0.3242686578487086 0.11084335351275833 138.26383343573016 163884.75248122576 0.04929810821155814 0.03338120656938476 5.256534465162836e-08 7.279300483731709 -0.1732083890615307 TDS(ph)PDMHEDT ddPTM_PC-9_AZD4547_30min_R2 2 TDSPDMHEDT 10 0 Q9BW61 Q9BW61 DDA1 DET1- and DDB1-associated protein 1 1 T(0.004)DS(0.995)PDMHEDT;T(0.022)DS(0.978)PDMHEDT 73.84100000000001 0.023691999999999998 12423200.0 18429.0 17189.6 19830.3 24602.2 20104.2 22563.1 15915.3 23761.3 17655.2 18969.4 True False 24289.038652987045 22745.802039050883 19567.337265112164 18930.542890200955 17313.078853752315 21152.22579015797 17331.730867978553 20089.537065354518 18588.41782819483 18305.287079835995 1.3268865190179067 1.242581006233237 1.0689445721212627 1.034157115790536 0.9457966312270165 1.1555254882321944 0.9468155725932399 1.0974718384768707 1.0154671569543816 1.0 14.159972778999503 -5.179686622081985 2.188241911909961 1.030255238278475 1.3285485455926525 0.7489116171881786 0.05967328221592674 0.16396271205602164 1.4032796012084436 0.015503165362016421 0.06768258869388455 6.6117036278341295e-06 5.179686622081985 0.29829330731417736 TDS(ph)PDMHEDT ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TDSPDMHEDT 10 0 Q9BW61 Q9BW61 DDA1 DET1- and DDB1-associated protein 1 1 T(0.021)DS(0.979)PDMHEDT;T(0.164)DS(0.836)PDMHEDT 91.54899999999999 0.007045 29533000.0 82188.0 73722.0 77525.0 95205.0 99474.0 77396.0 88314.0 89491.0 78743.0 66545.0 True False 96100.80511300669 81040.63294827525 79373.49001519983 89870.97250877475 79982.78378008385 73337.2175121288 79948.25858200926 87141.95607355215 79894.4674078796 78609.0817300697 1.2225152997334408 1.030932192116874 1.0097241726821715 1.1432644998624522 1.0174751061808762 0.9329356850135512 1.0170359050438738 1.1085482002293692 1.0163516180258116 1.0 16.262408376639648 -4.76104901134089 24.94224826433444 1.0330557909426963 1.2225155178848661 0.521907556725753 0.05503551866522163 7.836465824843325 500065.7170443071 0.01431676509918016 0.08136787398625785 1.7336083441881847e-05 4.76104901134089 0.18945972694216984 TDS(ph)PSCEYSR ddPTM_PC-9_AZD4547_30min_R2 1 TDSPSCEYSR 10 0 Q9HAV4 Q9HAV4 XPO5 Exportin-5 1 T(0.07)DS(0.929)PSCEYSR 99.34299999999999 0.0044101999999999995 5525800.0 148540.0 144870.0 152410.0 183080.0 166640.0 181310.0 168530.0 180970.0 166530.0 166580.0 True False 195772.63017606505 191696.39441274383 150388.94381707514 140873.7345578034 143504.91241577832 169972.65703797576 183528.8435141297 153005.2447768938 175332.43582226685 160748.08490300606 1.2178846814516795 1.192526769624731 0.935556674953972 0.8763633771612603 0.8927317081405224 1.0573852692586398 1.1417171384957359 0.9518324580303135 1.0907279917397514 1.0 17.29444202432351 -5.248197013395105 21.784737649901665 0.9913919313347492 1.2052060602766683 0.5254625677891638 0.08053818434938813 118.79070338762163 195413.52499745102 0.022608504602647 0.05872360000006688 5.64680754862993e-06 5.248197013395105 0.2138141289419191 TDS(ph)PSCEYSR ddPTM_PC-9_Lapatinib_30min_R1 1 TDSPSCEYSR 10 0 Q9HAV4 Q9HAV4 XPO5 Exportin-5 1 T(0.004)DS(0.662)PS(0.334)CEYSR 91.70100000000001 0.008151 4991300.0 358340.0 453690.0 422880.0 407010.0 505520.0 471200.0 473870.0 485380.0 498530.0 406650.0 True False 353230.0058884927 452639.50867963035 388112.438764005 436942.8731455583 475786.30749056 451047.87442084885 498404.6699362825 507932.5267668076 442380.30164636753 476938.910672935 0.7406189723335935 0.9490513324672556 0.8137571292231103 0.9161401247993282 0.9975833316246964 0.9457141456218044 1.045007355833183 1.0649844569195293 0.9275408060587735 1.0 18.863444963071586 -6.002876745826419 0.9671018347252416 1.011140447144661 0.821569574281544 0.581318343726251 0.06141672173508399 0.4336668465885404 0.8228804580899592 0.0257385848308347 0.05602219851793514 9.933979379547145e-07 6.002876745826419 -0.18957087286311702 TDS(ph)QSVRHSPIAPSSPSPQVLAQK ddPTM_PC-9_Lapatinib_30min_R1 1 TDSQSVRHSPIAPSSPSPQVLAQK 24 1 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 T(0.015)DS(0.333)QS(0.333)VRHS(0.318)PIAPSSPSPQVLAQK 69.922 0.002932 0.0 5131.7 3387.0 8824.8 4302.9 6733.5 7654.7 3462.3 4768.7 8635.7 2759.3 True False 5058.521016961476 3379.15760959666 8099.259008713108 4619.349620053613 6337.448768570345 7327.326324977227 3641.560952835993 4990.271210995244 7663.056528047539 3236.241328463862 1.5630852286787247 1.0441611939986677 2.5026746112773863 1.4273810730444714 1.9582744688507285 2.264147071026767 1.1252439429677894 1.5419960084880204 2.3678878520734243 1.0 11.660103479079032 -10.958626902684212 6.823393860669303 0.9998951551529833 1.7426009623785024 0.18017198817934166 0.48249359325156577 0.0007531022105987074 6.227696245284028e-05 0.457081976413928 0.11084331377048715 1.0999503881774208e-11 10.958626902684212 0.742705807225519 TDS(ph)QTIGDFATR ddPTM_PC-9_AZD4547_30min_R2 2 TDSQTIGDFATR 12 0 Q13480-2 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 T(0.066)DS(0.589)QT(0.345)IGDFATR;T(0.018)DS(0.956)QT(0.002)IGDFAT(0.025)R 127.3 0.00023828 7224300.0 26142.0 27258.0 33292.0 38097.0 39924.0 35164.0 34922.0 37711.0 31827.0 30470.0 True False 34454.61221262071 36068.61544075772 32850.526327393636 29314.325242782597 34381.24173840327 32965.18952117018 38029.99034712179 31883.63146257086 33509.31024389172 29403.25457434621 1.1717958678860576 1.2266878603373013 1.1172411626859533 0.9969755276124704 1.1693005497561573 1.1211408396243214 1.2933939081798873 1.0843572224956597 1.1396462986491287 1.0 14.843688231835614 -8.997207700639253 1.522008429361543 1.0001813606456749 1.1486481369666612 0.2557364392481122 0.07536152799588319 3.73268598288655 10.396343210068407 0.07493911059814452 0.021587109402035287 1.006450220531667e-09 8.997207700639253 0.14846677632098637 TDS(ph)QTIGDFATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TDSQTIGDFATR 12 0 Q13480-2 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 T(0.302)DS(0.672)QT(0.018)IGDFAT(0.007)R;T(0.1)DS(0.9)QTIGDFATR 140.03 7.4206e-05 19424700.0 33116.0 29800.0 29362.0 40538.0 51551.0 38449.0 41301.0 52839.0 37228.0 34322.0 True False 38721.88472918582 32758.347058661002 30062.101436005098 38266.78728596922 41449.95161194988 36432.666754403894 37388.6702866541 51452.03223754822 37772.389071543425 40544.30690719748 0.9550510955290705 0.8079641645778312 0.7414629507618598 0.9438264014121314 1.0223371608454264 0.8985889643592925 0.9221681942235104 1.2690322307227402 0.9316323783262902 1.0 15.307211729913698 -6.6199003778546555 0.847421753791842 1.052677019868804 0.8388462226105906 0.29136211040031235 0.11199141231454433 0.7248523109081074 1.147609189972921 0.06943790235500512 0.07620582738166437 2.399383246741903e-07 6.6199003778546555 -0.2138307972582134 TDS(ph)QTIGDFATR ddPTM_PC-9_Lapatinib_30min_R1 2 TDSQTIGDFATR 12 0 Q13480-2 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 T(0.002)DS(0.998)QTIGDFATR;T(0.104)DS(0.895)QT(0.001)IGDFATR 117.2 0.00064156 8110700.0 21838.9 24327.0 25053.0 23600.0 20148.1 20356.5 25542.0 24972.0 23697.4 20987.8 True False 21527.473281236238 24270.672326146436 22993.23904737667 25335.622727292128 18963.02837068869 19485.899948319202 26864.439782034176 26132.290284768012 21028.3492673152 24615.51326551437 0.874549031297089 0.9859909100554467 0.9340954543324327 1.0292542939897422 0.770369001293804 0.7916105481179785 1.0913621622373597 1.0616187443622638 0.8542722242064851 1.0 14.587280201506637 -7.270902513225882 24.993992445780812 1.0069481696041547 0.9035144243769977 0.2260211604479423 0.09386697399900845 1153.5847441164185 3046830.846961628 0.041106939218195596 0.028106878078876383 5.359169421422327e-08 7.270902513225882 -0.10343374522715698 TDS(ph)SPNQAR ddPTM_PC-9_AZD4547_30min_R2 2 TDSSPNQAR 9 0 A6NLN1;P26599;P26599-2;P26599-3;K7ES59;A0A087WU68 A6NLN1 PTBP1 Polypyrimidine tract-binding protein 1 1 T(0.095)DS(0.868)S(0.037)PNQAR;T(0.007)DS(0.844)S(0.149)PNQAR 115.0 0.0020050000000000003 356670000.0 42827.0 34730.0 31141.0 36055.0 34984.0 27461.3 24708.8 33571.0 42103.0 48867.0 True False 56445.09514306129 45955.79331783387 30728.04999283205 27743.076794197073 30127.07546779632 25744.140569835912 26907.83533271184 28383.373334835065 44328.47862502191 47156.18120395718 1.1969818950972353 0.9745444212089299 0.6516229518231951 0.5883232290206946 0.6388786093066451 0.5459335322020425 0.5706109919361712 0.6019014392211478 0.9400353780407905 1.0 15.525159270445874 -5.053237796890749 2.5970594239672136 0.661709744687461 1.1966061417422886 0.5382693235075744 0.15016773122049698 0.21642662070788468 2.6167164050149005 0.0387064479380756 0.19287029806817463 8.846310995826815e-06 5.053237796890749 0.5348963970548276 TDS(ph)SPNQAR ddPTM_PC-9_Lapatinib_30min_R1 1 TDSSPNQAR 9 0 A6NLN1;P26599;P26599-2;P26599-3;K7ES59;A0A087WU68 A6NLN1 PTBP1 Polypyrimidine tract-binding protein 1 1 T(0.011)DS(0.719)S(0.271)PNQAR 108.31 0.0024439 272270000.0 36370.0 74546.0 42117.0 58022.0 73127.0 37653.0 115290.0 107650.0 77482.0 49990.0 True False 35851.357130558856 74373.39331709265 38654.302836321505 62289.13143571792 68825.81363321366 36042.66896343001 121259.15208169763 112651.81199564593 68755.16123836863 58630.70489251205 0.6114775047696479 1.2685058699778853 0.6592842932246273 1.0623977922474732 1.1738868526208641 0.6147405020885764 2.0681851310504045 1.9213791170031307 1.172681811764293 1.0 15.83936878130888 -7.25425354977428 24.98913339966623 1.617343113869896 0.924316056793225 0.41823923486327796 0.36582762544262437 498.18660225061035 1732476.0023716977 0.1369267861463683 0.10384068854911976 5.5686054772537336e-08 7.25425354977428 -0.6930270570766709 TDS(ph)SPNQAVR ddPTM_PC-9_AZD4547_30min_R2 1 TDSSPNQAVR 10 0 A0A0U1RRM4 A0A0U1RRM4 1 T(0.005)DS(0.675)S(0.32)PNQAVR 81.565 0.01611 2177900.0 18210.0 17300.0 26013.0 27581.0 24397.0 22647.0 20260.0 25789.0 18929.0 23401.0 True False 24000.401208470026 22891.88668006121 25668.050623407747 21222.62657220218 21009.897672874085 21230.879509894803 22063.100751179416 21803.902622265094 19929.54829568059 22581.738112710038 1.062823467736591 1.0137344860613986 1.136672938783246 0.9398136877806192 0.9303932924918986 0.9401791573317861 0.9770328856467116 0.9655546669365037 0.8825515642865119 1.0 14.462868913936772 -5.782595211950864 24.999090628374894 0.9466556248825364 1.065342716272073 0.6600382808949585 0.04043005439958687 134.46738001600536 158894.78612562697 0.011015997653505456 0.016358209853015778 1.6496992921266336e-06 5.782595211950864 0.11868709138953659 TDS(ph)TSDGRPAWMR ddPTM_PC-9_AZD4547_30min_R2 1 TDSTSDGRPAWMR 13 1 Q14204;A0A2R8Y706;A0A2R8Y5T0;A0A2R8Y542;A0A2R8Y6I5 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 1 T(0.001)DS(0.455)T(0.455)S(0.089)DGRPAWMR 77.64399999999999 0.034486 78469000.0 58583.0 53664.0 60965.0 83214.0 70382.0 60059.0 60059.0 61971.0 56239.0 66683.0 True False 77211.17539790212 71009.83854328362 60156.56426617667 64030.297943483965 60610.67418175277 56303.50123569442 65404.134650300264 52394.805901911284 59211.67872580598 64348.44846672562 1.1998917959588067 1.1035206012776297 0.9348564837158962 0.9950558167162932 0.941913529012193 0.8749783806335095 1.0164057752553357 0.8142357298483192 0.9201725936939125 1.0 15.973617742970626 -4.689455786500071 0.9631044609370794 0.9224097999007326 1.404220123809677 0.688042295185993 0.05888123651280819 1.2580204245154205 0.8245197369907781 0.019142377167913747 0.6605338707174873 2.0442980458784245e-05 4.689455786500071 0.4818103239089444 TDS(ph)TSDGRPAWMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TDSTSDGRPAWMR 13 1 Q14204;A0A2R8Y706;A0A2R8Y5T0;A0A2R8Y542;A0A2R8Y6I5 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 1 T(0.024)DS(0.89)T(0.043)S(0.043)DGRPAWMR;T(0.056)DS(0.841)T(0.052)S(0.052)DGRPAWMR;T(0.001)DS(0.99)T(0.008)S(0.001)DGRPAWMR 92.906 0.0095193 84089000.0 75630.0 82715.0 89543.0 99729.0 112443.0 113715.0 126915.0 108036.0 103003.0 90796.0 True False 88432.66523941055 90926.39855560893 91678.04471371853 94141.50745578046 90410.60132882925 107751.58521618342 114892.69241497086 105200.16947360388 104509.22401246901 107256.59605925951 0.8244962873010747 0.8477464500679464 0.8547543748551018 0.877722311863851 0.8429374476780634 1.0046149996840328 1.0711946550260871 0.9808270385112776 0.9743850527824641 1.0 16.710706847656894 -6.76432282955037 24.4991566428767 1.009067970326882 0.8512885253536804 0.8913519831851658 0.027336981948668657 18.805603601549453 159779.50984313048 0.009937380587487476 0.009153065511616758 1.7205891124754926e-07 6.76432282955037 -0.1577794449732015 TDS(ph)TSDGRPAWMR ddPTM_PC-9_Lapatinib_30min_R1 2 TDSTSDGRPAWMR 13 1 Q14204;A0A2R8Y706;A0A2R8Y5T0;A0A2R8Y542;A0A2R8Y6I5 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 1 T(0.004)DS(0.672)T(0.212)S(0.111)DGRPAWMR;T(0.125)DS(0.798)T(0.039)S(0.039)DGRPAWMR 70.47 0.013272999999999998 20977000.0 67397.0 64350.0 52640.0 61932.0 64448.0 80927.0 78145.0 80599.0 81312.0 79264.0 True False 66435.90642090382 64201.00152865222 48312.14239627616 66486.68587909566 60657.29534964308 77465.94086005099 82190.9657335785 84343.92378111552 72153.78630668066 92964.67678735907 0.7146360178593928 0.6905956514591141 0.5196827877623024 0.715182241005072 0.6524768056622877 0.8332836033759488 0.8841096271606085 0.9072685098883089 0.776141958431375 1.0 16.50439502798436 -6.835455040015083 3.270124434864683 0.8824394718283154 0.6537010167712013 0.7018707637450183 0.07277491953667024 0.1408527282420807 3.023229234063404 0.026594786410862915 0.02374096128952101 1.4606459538056213e-07 6.835455040015083 -0.2287384550571141 TDS(ph)VKTPESEGNPLLEQLEK ddPTM_PC-9_AZD4547_30min_R2 3 TDSVKTPESEGNPLLEQLEK 20 1 Q8WYK2;Q8WYK2-2 Q8WYK2 JDP2 Jun dimerization protein 2 1 T(0.014)DS(0.626)VKT(0.357)PES(0.003)EGNPLLEQLEK;T(0.043)DS(0.522)VKT(0.423)PES(0.012)EGNPLLEQLEK;T(0.12)DS(0.525)VKT(0.326)PES(0.028)EGNPLLEQLEK 119.28 6.3233e-06 48939800.0 53235.0 67873.0 59684.0 72010.0 85635.0 88076.0 81297.0 81387.0 84161.0 89122.0 True False 70162.62264321258 89811.61992114424 58892.551163167154 55409.207043409566 73746.0584176978 82568.59379668348 88532.27550684272 68810.50923720536 88609.57864191326 86001.8659066257 0.8158267486822883 1.0442985041586759 0.6847822491096672 0.6442791264967284 0.8574937024943817 0.9600790974271441 1.0294227290715339 0.8001048408869942 1.0303215832330757 1.0 16.3920803405855 -6.631746720669639 4.4897227883800355 0.9549853552192964 0.8010616677940724 0.3135507796024599 0.11627949703977104 0.31038124518595417 10.822618773723793 0.041544027149814776 0.041414237490908355 2.3348193254174816e-07 6.631746720669639 -0.153923687425224 TDS(ph)VKTPESEGNPLLEQLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TDSVKTPESEGNPLLEQLEK 20 1 Q8WYK2;Q8WYK2-2 Q8WYK2 JDP2 Jun dimerization protein 2 1 T(0.095)DS(0.762)VKT(0.142)PESEGNPLLEQLEK;T(0.103)DS(0.691)VKT(0.204)PES(0.002)EGNPLLEQLEK 113.86 1.034e-05 17795900.0 47839.0 56684.0 37437.9 66285.0 65353.0 40535.0 69614.0 46949.0 51715.0 50430.0 True False 55937.1978366808 62311.21290849465 38330.561520026415 62571.26634886942 52547.54879043593 38409.27324221072 63019.65795828525 45716.638496577376 52471.234039832125 59572.55979633963 0.9389758980965899 1.0459717212340318 0.643426464316237 1.0503370438131492 0.8820763950731669 0.6447477391188206 1.0578638583557631 0.7674110136087586 0.8807953564395291 1.0 15.862360331683483 TDS(ph)VKTPESEGNPLLEQLEKK ddPTM_PC-9_AZD4547_30min_R2 1 TDSVKTPESEGNPLLEQLEKK 21 2 Q8WYK2;Q8WYK2-2 Q8WYK2 JDP2 Jun dimerization protein 2 1 T(0.316)DS(0.377)VKT(0.266)PES(0.041)EGNPLLEQLEKK 64.26 0.0014960999999999998 10289000.0 25599.0 16743.0 17467.0 41023.0 34012.0 32532.0 22514.0 22593.0 24670.0 30159.0 True False 33738.949507722355 22154.84732278989 17235.376167264934 31565.781149031947 29290.020889855037 30497.768897244576 24517.70238460282 19101.770985491305 25974.00583519682 29103.142589685147 1.159288877610085 0.7612527497508843 0.5922170127900059 1.084617616525702 1.0064212412660936 1.0479201276378214 0.8424417503727754 0.6563473661521843 0.8924811385971297 1.0 14.828887324908548 -7.5027650118191005 24.372870054417852 0.8145274721902519 0.9287509830156893 0.05160542643227428 0.17449488021709492 1547.444119111397 1875128.2146406819 0.07709516347897334 0.05118332091884323 3.1422084210100324e-08 7.5027650118191005 0.11422351082543736 TDSCSS(ph)AQAQYDTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDSCSSAQAQYDTPK 15 0 Q96PD2;Q96PD2-2 Q96PD2 DCBLD2 Discoidin, CUB and LCCL domain-containing protein 2 1 T(0.001)DS(0.026)CS(0.123)S(0.851)AQAQYDTPK 164.41 2.7561999999999997e-15 0.0 8007.4 7110.5 6980.5 4307.8 12269.0 6042.0 4210.1 5876.3 3357.9 7234.9 True False 9362.894666640981 7816.383448342585 7146.941593693673 4066.447932076036 9864.977523753436 5725.1468836668855 3811.2888495155657 5722.053351454504 3407.0029349773235 8546.530098563113 1.0955200015284705 0.9145680595750452 0.8362389778391179 0.47580104266639256 1.1542669843767341 0.6698796842275706 0.44594575875375897 0.6695177206965579 0.39864165874173035 1.0 13.061123087621931 -6.982587412830177 24.95563886801988 0.594832708861499 0.8739970545225237 0.2372045582154254 0.22795877459669492 326.64975849425934 468151.3214889487 0.07797488249663544 0.06875355998474186 1.0409085771641808e-07 6.982587412830177 0.27916434566102477 TDSLAAT(ph)PPAAK ddPTM_PC-9_AZD4547_30min_R2 2 TDSLAATPPAAK 12 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 T(0.337)DS(0.06)LAAT(0.602)PPAAK;T(0.029)DS(0.009)LAAT(0.962)PPAAK 135.02 0.00014458 25935000.0 81009.0 72993.0 93884.0 120337.0 117313.0 105733.0 103613.0 110980.0 100143.0 104597.0 True False 106768.1769081243 96586.55979408714 92639.03681728407 92595.16383811661 101026.1149197803 99121.4987954123 112834.3562750223 93830.59106669444 105436.35453401342 100935.09086684913 1.057790467033611 0.9569175493337747 0.9178080291173563 0.9173733638409824 1.0009018078068732 0.9820320955193941 1.117890272906876 0.9296131826985051 1.0445956270362131 1.0 16.623068300203222 -6.63588756326228 2.6621771574950324 1.0180201610243518 0.9595389518735754 0.14801824719451284 0.05792304114640502 0.5065325458571385 7.283341561334165 0.020916945326711466 0.020870902785198146 2.3126634500422702e-07 6.63588756326228 -0.05848120915077637 TDSLAAT(ph)PPAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TDSLAATPPAAK 12 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 TDS(0.026)LAAT(0.974)PPAAK;TDS(0.006)LAAT(0.994)PPAAK 105.19 0.004451 27663000.0 85102.0 89476.0 84951.0 110317.0 127701.0 125672.0 132900.0 132400.0 123430.0 101565.0 True False 99508.0877588831 98358.58595371679 86976.5540184616 104136.2961425396 102678.90575929871 119081.53908708782 120310.74988732317 128924.64028939587 125234.93024338155 119977.93051190229 0.8293865991380098 0.8198056553739208 0.7249379418978491 0.8679620968475438 0.8558149429749712 0.9925286973946801 1.0027740049690876 1.0745696290919606 1.0438163894730434 1.0 16.872409526360308 -6.7231723174989595 1.4210747552183605 1.0419029219543514 0.7992396642599403 0.8797784215768517 0.038116213649142694 0.12528232765948494 0.5281347654070317 0.017087703916764622 0.015975663574620373 1.8915929316098217e-07 6.7231723174989595 -0.2426632576944111 TDSLAAT(ph)PPAAK ddPTM_PC-9_Lapatinib_30min_R1 2 TDSLAATPPAAK 12 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 T(0.221)DS(0.072)LAAT(0.707)PPAAK;T(0.001)DS(0.003)LAAT(0.997)PPAAK 115.57 0.0017518 24370000.0 81414.0 85610.0 87432.0 98161.0 101807.0 102726.0 101057.0 106020.0 118359.0 103812.0 True False 80253.02143050077 85411.77530486269 80243.6784572798 105380.08739549696 95818.91242026303 98332.64844600184 106289.2369843014 110946.07624503852 105028.16304447567 121755.76587920489 0.659131178314139 0.7015008668221969 0.659054442948438 0.8655038768352507 0.7869763844722223 0.8076221091948832 0.8729708709627109 0.9112182527364596 0.8626134646360416 1.0 16.893630568784417 -3.01921142332777 0.15093994885678164 1.0415378720620758 1.4050635914894022e-10 0.8337441739417994 0.043524227741518574 16.629538341104507 0.2492707784751797 0.16923308331234935 3.5249620580585486 0.0009567282032890839 3.01921142332777 -1.0415378719215695 TDSQS(ph)VRHSPIAPSSPSPQVLAQK ddPTM_PC-9_AZD4547_30min_R2 1 TDSQSVRHSPIAPSSPSPQVLAQK 24 1 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 T(0.013)DS(0.088)QS(0.45)VRHS(0.45)PIAPSSPSPQVLAQK 77.631 9.919e-05 7411800.0 1782.4 0.0 7674.7 24205.0 14385.0 12990.0 6007.7 12725.0 8277.9 14303.0 True False 2349.1661237768794 0.0 7572.928463440099 18624.91121352213 12387.891053174308 12177.733246502128 6542.373661542967 10758.643641410043 8715.452894332211 13802.256323494375 0.1702016010076627 0.0 0.548673223127248 1.3494106164235313 0.8975265176091161 0.8823001805706967 0.47400754689698493 0.7794844110449205 0.631451314195394 1.0 13.752616510366712 -5.4482869437591495 4.599169510771754 0.8441652359969475 0.10244200619196739 0.6558572731799781 0.22203514507955083 0.1375211450673828 5.365127951978369 0.06302980761963337 0.134323947306949 3.562156995200484e-06 5.4482869437591495 -0.7417232298049801 TDSQSVRHS(ph)PIAPSSPSPQVLAQK ddPTM_PC-9_AZD4547_30min_R2 1 TDSQSVRHSPIAPSSPSPQVLAQK 24 1 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 T(0.043)DS(0.05)QS(0.148)VRHS(0.76)PIAPSSPSPQVLAQK 71.524 0.0023808 0.0 869.16 1089.0 4793.1 12841.0 7262.2 6309.3 3492.6 8448.9 4655.6 7963.6 True False 1145.5348003489175 1440.9979534443155 4729.540362244093 9880.705841472323 6253.968884696731 5914.778473607072 3803.434633937277 7143.3166414074085 4901.685511404228 7684.796787931189 0.14906507380233602 0.18751282476426342 0.6154411746673296 1.2857471855325782 0.8138105739527761 0.7696727235385203 0.494929760525417 0.9295387813801188 0.6378419165360653 1.0 12.907791395336737 -5.357774221633337 3.7327811039417296 0.8315973180343608 0.16182502544285424 0.6351184459343195 0.20228866863432562 0.14638318409670784 3.709830606195223 0.055720916967980316 0.12994116410469525 4.38758737710591e-06 5.357774221633337 -0.6697722925915065 TDSQT(ph)IGDFATR ddPTM_PC-9_AZD4547_30min_R2 1 TDSQTIGDFATR 12 0 Q13480-2 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 TDS(0.296)QT(0.703)IGDFATR 147.39 0.00033074 21137000.0 13370.0 13957.0 18921.0 23138.0 24833.0 14568.0 16203.0 21405.0 17168.0 18558.0 True False 17621.381886724004 18468.32730598927 18670.09517723823 17803.89157853647 21385.366598781893 13657.060657047177 17645.035610629813 18097.349087967148 18075.46543083335 17908.290068615588 0.9839790297793761 1.0312725131895844 1.0425392433171332 0.9941703820030212 1.1941601636361647 0.7626110926682653 0.9852998551521605 1.0105570670693393 1.009335082332106 1.0 14.128339971072187 -6.742391729097697 24.99996557728109 0.956203995917628 1.0447969157096582 0.23322993397557756 0.08647507498497388 407.5884338773245 534957.094700957 0.028490295741986343 0.028446722171565568 1.8097070193469425e-07 6.742391729097697 0.08859291979203021 TDSREDEIS(ph)PPPPNPVVK ddPTM_PC-9_AZD4547_30min_R2 10 TDSREDEISPPPPNPVVK 18 1 K7EMU2;K7EMZ6;K7EIE5;K7EID3;K7EJ40;K7EK41;K7EPB2;P10644-2;P10644 K7EMU2 PRKAR1A cAMP-dependent protein kinase type I-alpha regulatory subunit;cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed 1 TDSREDEIS(1)PPPPNPVVK;TDSREDEIS(1)PPPPNPVVK;T(0.001)DS(0.006)REDEIS(0.993)PPPPNPVVK;TDSREDEIS(1)PPPPNPVVK;TDSREDEIS(1)PPPPNPVVK;T(0.019)DS(0.102)REDEIS(0.879)PPPPNPVVK;TDSREDEIS(1)PPPPNPVVK;TDSREDEIS(1)PPPPNPVVK;TDSREDEIS(1)PPPPNPVVK;TDSREDEIS(1)PPPPNPVVK 186.36 5.7325e-10 2621601000.0 650100.0 675555.0 783900.0 1129403.0 948572.0 897533.0 726256.5 900795.0 703742.0 874509.0 True False 856818.2770799751 893914.9425519501 773504.9738088383 869036.5874524089 816879.1513445713 841410.1196253104 790891.9215547362 761597.8309598408 740940.3654022315 843892.7060898242 1.0153166047020854 1.0592755881181908 0.9165916096050558 1.0297951163473007 0.967989349178736 0.9970581728617884 0.937194877793568 0.9024818267344712 0.8780030447654628 1.0 19.686700058402458 -7.340402501693186 3.1586328355498257 0.9176526576892443 0.9975113664094325 0.3404572908625769 0.046073019093004514 0.27412326018035305 5.3268410878038495 0.020618903059917374 0.01333659413961846 4.5666475908788706e-08 7.340402501693186 0.07985870872018819 TDSREDEIS(ph)PPPPNPVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 9 TDSREDEISPPPPNPVVK 18 1 K7EMU2;K7EMZ6;K7EIE5;K7EID3;K7EJ40;K7EK41;K7EPB2;P10644-2;P10644 K7EMU2 PRKAR1A cAMP-dependent protein kinase type I-alpha regulatory subunit;cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed 1 TDS(0.001)REDEIS(0.999)PPPPNPVVK;TDSREDEIS(1)PPPPNPVVK;TDSREDEIS(1)PPPPNPVVK;TDS(0.001)REDEIS(0.999)PPPPNPVVK;TDSREDEIS(1)PPPPNPVVK;TDSREDEIS(1)PPPPNPVVK;TDSREDEIS(1)PPPPNPVVK;T(0.041)DS(0.233)REDEIS(0.725)PPPPNPVVK;TDSREDEIS(1)PPPPNPVVK 171.39 2.6432e-08 2181993000.0 1187460.0 1261816.0 1161356.0 1544881.0 1600514.0 1434469.0 1444089.0 1400336.0 1327434.0 1074122.0 True False 1388473.524595936 1387080.7534285728 1189047.1315071566 1458326.3261417784 1286904.7710858851 1359242.9204016498 1307294.4356210295 1363578.6637786338 1346845.2109915998 1268851.8158549273 1.0942755546757128 1.0931778920881987 0.9371048034525609 1.149327532119412 1.0142277884662159 1.0712385035173069 1.0302971704699815 1.07465556398316 1.0614676939908243 1.0 20.2750921617386 -8.701806568347058 0.005356129779525775 3.401592874349946e-08 2.0836309601300607 0.07509557984221582 0.054171235223415035 21541.562508542633 63.90427380103216 12544.173891830691 12311.05906469258 1.986979706839094e-09 8.701806568347058 2.083630926114132 TDSREDEIS(ph)PPPPNPVVK ddPTM_PC-9_Lapatinib_30min_R1 6 TDSREDEISPPPPNPVVK 18 1 K7EMU2;K7EMZ6;K7EIE5;K7EID3;K7EJ40;K7EK41;K7EPB2;P10644-2;P10644 K7EMU2 PRKAR1A cAMP-dependent protein kinase type I-alpha regulatory subunit;cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed 1 T(0.002)DS(0.077)REDEIS(0.921)PPPPNPVVK;T(0.001)DS(0.004)REDEIS(0.996)PPPPNPVVK;TDS(0.001)REDEIS(0.999)PPPPNPVVK;TDSREDEIS(1)PPPPNPVVK;T(0.001)DS(0.021)REDEIS(0.978)PPPPNPVVK;TDSREDEIS(1)PPPPNPVVK 173.03 1.5162999999999998e-08 2486686000.0 936537.0 921847.0 906647.0 798926.0 849422.0 794661.0 728719.0 717413.0 863109.0 676225.0 True False 923181.8106401478 919712.51990961 832105.9834186297 857681.6831790064 799460.6679879066 760675.2014752679 766448.5041705491 750746.6270249193 765896.5754793 793109.5902368247 1.164002833914142 1.1596285446945376 1.049168984541166 1.0814163562476913 1.0080078186284263 0.9591047830453395 0.9663841083319714 0.9465862426411263 0.9656882036322385 1.0 19.597160702746095 -5.656503156109959 0.7438529931701104 0.9594381408833442 1.1974849373111915 0.8970762015718903 0.02470961318062329 0.3082167805202671 0.2761767173800287 0.011895744420304468 0.0509562245428543 2.2054481088761176e-06 5.656503156109959 0.23804679642784732 TDSS(ph)PNQAR ddPTM_PC-9_AZD4547_30min_R2 2 TDSSPNQAR 9 0 A6NLN1;P26599;P26599-2;P26599-3;K7ES59;A0A087WU68 A6NLN1 PTBP1 Polypyrimidine tract-binding protein 1 1 T(0.295)DS(0.1)S(0.605)PNQAR;TDS(0.045)S(0.955)PNQAR 103.08 0.0029698 3931100.0 21551.3 16284.099999999999 11365.599999999999 14843.0 13376.0 10735.8 9424.5 11664.900000000001 18632.7 23451.6 True False 28404.165105112552 21547.616872068495 11214.884717848883 11421.175672063999 11518.97328656654 10064.488728852775 10263.262242324305 9862.357737735483 19617.586482589035 22630.5666221115 1.2551239029675856 0.9521465914607329 0.49556358464711303 0.5046791740912393 0.5090006573371332 0.44472986014495686 0.45351326874407316 0.4357980912461703 0.8668623640833372 1.0 14.465985086676413 -5.035070641455455 2.780198478507175 0.5525901157789421 1.2510434709363634 0.5670070565297627 0.18623858453479075 0.18735844344917818 2.6561769411622245 0.04667301276801497 0.22818391528529527 9.22421375770223e-06 5.035070641455455 0.6984533551574212 TDSS(ph)PNQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TDSSPNQAR 9 0 A6NLN1;P26599;P26599-2;P26599-3;K7ES59;A0A087WU68 A6NLN1 PTBP1 Polypyrimidine tract-binding protein 1 1 TDS(0.204)S(0.796)PNQAR;T(0.315)DS(0.222)S(0.463)PNQAR;T(0.023)DS(0.203)S(0.775)PNQAR 166.69 0.0010493 157032500.0 148600.8 348747.0 260773.0 166960.4 721550.0 709222.0 252276.0 359050.0 599930.0 792666.0 True False 173755.98044041547 383368.29737137153 266990.81730710925 157606.15008092043 580167.4571900156 672029.1498060246 228378.59095992704 349625.3179449213 608702.8412939463 936370.0710593968 0.18556336411289848 0.40941963996951936 0.2851338648671666 0.16831609099018607 0.6195920556640835 0.7176961017620946 0.2438977900068319 0.3733836959882323 0.6500665282960911 1.0 19.836719297156463 -14.522878745273882 0.12696858123361418 3.005473383933863 0.14297056724687826 0.5907259031199688 0.1652295901897748 115.28839575947157 0.9278820790124958 58.701988794665304 1.4453843572333254 3.0000000000445926e-15 14.522878745273882 -2.862502816686985 TDSS(ph)PNQAR ddPTM_PC-9_Lapatinib_30min_R1 3 TDSSPNQAR 9 0 A6NLN1;P26599;P26599-2;P26599-3;K7ES59;A0A087WU68 A6NLN1 PTBP1 Polypyrimidine tract-binding protein 1 1 T(0.005)DS(0.264)S(0.731)PNQAR;TDS(0.314)S(0.686)PNQAR;T(0.016)DS(0.142)S(0.842)PNQAR 144.17 0.00056359 295087120.0 289854.54 628489.5 382492.4 555752.0 696410.9 325934.2 1241967.4 1112650.3 596902.7999999999 599388.6 True False 285721.16110678675 627034.2711770303 351045.3513353607 596623.8560143245 655449.380058508 311994.7540557297 1306270.3949788387 1164348.0948676206 529673.3209988596 702992.1208748919 0.40643579440292926 0.8919506386453805 0.49935887033623605 0.848692095256787 0.9323708767073866 0.4438097452179751 1.8581579454306707 1.65627474376037 0.7534555584202955 1.0 19.423148994120936 -7.248732633588822 24.973922257350527 1.3716616471529617 0.6927375648669173 0.46418940591645286 0.33775073409720807 646.9817505925496 1271584.0530498994 0.12777091007607858 0.09830174126736138 5.63984757114081e-08 7.248732633588822 -0.6789240822860444 TDSS(ph)PNQAVR ddPTM_PC-9_AZD4547_30min_R2 1 TDSSPNQAVR 10 0 A0A0U1RRM4 A0A0U1RRM4 1 T(0.004)DS(0.218)S(0.779)PNQAVR 87.21600000000001 0.025691000000000002 0.0 18714.0 22827.0 30864.0 41458.0 29802.0 24423.0 23201.0 31316.0 22620.0 28646.0 True False 24664.662724618767 30205.381343685407 30454.723193820642 31900.49861971494 25664.506719965317 22895.825949139427 25265.84405370747 26476.831770090113 23815.647020354758 27643.112259163816 0.8922534660127613 1.0926910494194513 1.101711084782965 1.1540125554835015 0.9284231992169195 0.8282651292836738 0.9140014270763499 0.9578093639334306 0.8615400030602475 1.0 14.754632433339719 -6.390252634794285 6.760964947095164 0.9066044960476819 1.064913162193794 0.4587449430976843 0.07715290342420196 0.21543117176261148 10.908387245350902 0.024176834655817957 0.027404133940376284 4.071433682686044e-07 6.390252634794285 0.15830866614611205 TDSS(ph)PNQAVR ddPTM_PC-9_Lapatinib_30min_R1 1 TDSSPNQAVR 10 0 A0A0U1RRM4 A0A0U1RRM4 1 TDS(0.163)S(0.836)PNQAVR 103.43 0.0028334 4259800.0 29149.0 29695.0 28055.0 24021.0 25341.0 28865.0 23307.0 25228.0 29228.0 22579.0 True False 28733.329914728078 29626.243051955345 25748.42619543176 25787.584471706963 23850.4922023229 27630.511237601455 24513.722417973157 26400.18497934197 25936.034855515292 26481.75006537365 1.0850238312723333 1.1187418874817225 0.9723083305245467 0.9737870196662589 0.9006388227154495 1.0433793525500368 0.9256836257973072 0.9969199510670433 0.9793927815000448 1.0 14.692710846377624 -5.266084637402716 24.826375465892106 0.9720263680814561 1.1018828652142765 0.6452868376478035 0.03789880275125159 179.63910323548137 960079.136679875 0.009343606467680652 0.020492903859066856 5.418952729466347e-06 5.266084637402716 0.12985649713282033 TDSTESSGTQS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDSTESSGTQSPK 13 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 TDSTESS(0.002)GT(0.007)QS(0.991)PK 104.81 0.002956 0.0 2930.6 4349.8 4983.0 4332.6 7119.3 4743.2 4524.8 4719.1 6005.8 4839.5 True False 3426.6926980115945 4781.619397173278 5101.813618132737 4089.85846847872 5724.324271322668 4494.458242073616 4096.178187284868 4595.228625299759 6093.623463142675 5716.863040539076 0.5994008731208771 0.8364061484884535 0.8924148754229484 0.7154025624677313 1.0013051267330848 0.7861756019346245 0.7165080146643876 0.8038024687165584 1.0659033494299126 1.0 12.481008012558048 -2.70361761691376 0.05155322036147339 1.3491076456200999 5.769685887115447e-16 0.3169915098619539 0.11636484693024768 539.7345021598219 2.61707422430856 18.124452666850082 62.07305840325256 0.0019787110682933967 2.70361761691376 -1.3491076456200992 TDSTESSGTQS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 TDSTESSGTQSPK 13 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 TDSTESSGT(0.001)QS(0.999)PK 161.49 2.0377e-12 0.0 10958.0 20719.0 10767.0 15218.0 15070.0 13940.0 21770.0 17154.0 15215.0 12916.0 True False 10801.736910548916 20671.02642847156 9881.77882182192 16337.182485759822 14183.612228759965 13343.818695727143 22897.144078571906 17951.037463755838 13501.326478947092 15148.513390511802 0.7130559040410217 1.3645580853774573 0.6523266387321758 1.0784677060121648 0.9363039040942329 0.8808665478742607 1.511510964033832 1.1850032409780475 0.8912641214948249 1.0 13.886888600351973 TDSVIIADQTPT(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 1 TDSVIIADQTPTPTR 15 0 K7ELQ4;P17544-2;P17544;P17544-4;P17544-3;P17544-1;K7ESA4;P17544-5 K7ELQ4 ATF7 Cyclic AMP-dependent transcription factor ATF-7 1 TDSVIIADQT(0.003)PT(0.997)PTR 218.34 1.5898e-17 21385000.0 16836.0 11355.0 17675.0 31619.0 26347.0 21487.0 18046.0 22376.0 15730.0 23182.0 True False 22189.49778944542 15025.281690872549 17440.61795136015 24329.728058680277 22689.173832324184 20143.414493271055 19652.059040265733 18918.30334932739 16561.455686568534 22370.405236051647 0.9919130903219098 0.6716588963108339 0.7796290575574034 1.0875854863581562 1.0142495673595942 0.9004492444691335 0.8784847137500625 0.8456844276937404 0.7403288188932072 1.0 14.449303770356263 TDSVIIADQTPT(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TDSVIIADQTPTPTR 15 0 K7ELQ4;P17544-2;P17544;P17544-4;P17544-3;P17544-1;K7ESA4;P17544-5 K7ELQ4 ATF7 Cyclic AMP-dependent transcription factor ATF-7 1 TDSVIIADQT(0.212)PT(0.785)PT(0.003)R;TDSVIIADQTPT(0.999)PTR;TDSVIIADQT(0.001)PT(0.998)PTR;TDSVIIADQT(0.008)PT(0.679)PT(0.313)R 193.31 3.7722e-09 36582200.0 83634.0 71765.0 75437.0 81951.0 106872.0 100541.0 104195.0 101389.0 86333.0 77946.0 True False 97791.58435320483 78889.35492163796 77235.70417641578 77359.55115872661 85931.19878707126 95268.45296768499 94324.89529352631 98727.6461805254 87595.45679901037 92076.99277980343 1.0620631864799006 0.8567759712819585 0.8388165365165683 0.8401615737356595 0.9332537498544347 1.034660777807044 1.0244132920272342 1.0722292637926023 0.9513283845888583 1.0 16.490553095594407 -6.628667217366869 4.17612468257445 1.0212746757986821 0.8914352731261682 0.41134233851106927 0.06636041657115475 0.2062110595999302 6.52340957367621 0.022809765003847893 0.02275870269424221 2.351433941245017e-07 6.628667217366869 -0.12983940267251393 TDSVIIADQTPT(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 2 TDSVIIADQTPTPTR 15 0 K7ELQ4;P17544-2;P17544;P17544-4;P17544-3;P17544-1;K7ESA4;P17544-5 K7ELQ4 ATF7 Cyclic AMP-dependent transcription factor ATF-7 1 TDSVIIADQTPT(0.957)PT(0.043)R;TDSVIIADQTPT(0.991)PT(0.009)R 142.57 0.00022446 38371000.0 34148.0 29925.0 36502.0 28299.0 32431.0 34841.0 30882.0 34502.0 33924.0 25703.8 True False 33661.04325802374 29855.710501086513 33500.94646179471 30380.20286269662 30523.47234179921 33350.93164833784 32480.918853213512 36105.08887574347 30103.121884443037 30146.66758183936 1.116575925569348 0.9903486154825244 1.1112653287747134 1.0077466366796024 1.012499051808527 1.106289163065863 1.0774298275269512 1.1976477591670371 0.9985555386087663 1.0 14.879710914714122 -6.7746491283586945 24.9830444711327 1.0884277786191392 1.045814843017467 0.027254002423399815 0.0657206316760556 588.8946978903763 1113745.4220305427 0.021889013556787632 0.019427005577930208 1.680160891760175e-07 6.7746491283586945 -0.04261293560167223 TDSVKT(ph)PESEGNPLLEQLEK ddPTM_PC-9_AZD4547_30min_R2 1 TDSVKTPESEGNPLLEQLEK 20 1 Q8WYK2;Q8WYK2-2 Q8WYK2 JDP2 Jun dimerization protein 2 1 T(0.005)DS(0.425)VKT(0.561)PES(0.009)EGNPLLEQLEK 76.155 0.0015876 4781100.0 19462.0 22870.0 23799.0 25879.0 26128.0 27520.0 29009.0 25015.0 29790.0 30245.0 True False 25650.511165252236 30262.28025277457 23483.409710009633 19912.996376564322 22500.578202109038 25799.170049556447 31590.744802120596 21149.50653751451 31364.638582509655 29186.131755861526 0.878859568640876 1.0368719125204702 0.8046085005867007 0.6822759707635851 0.7709338938891821 0.8839530454177139 1.0823888916274815 0.7246423306256403 1.0746418485625664 1.0 14.832995392498443 -7.005959827094345 24.550409881384216 0.9525716789038344 0.8349646319617261 0.2020990814261019 0.12529303304267111 418.47447916301525 1723834.153072786 0.04676208546971923 0.039905249500568805 9.863707222159889e-08 7.005959827094345 -0.11760704694210833 TDSVKT(ph)PESEGNPLLEQLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TDSVKTPESEGNPLLEQLEK 20 1 Q8WYK2;Q8WYK2-2 Q8WYK2 JDP2 Jun dimerization protein 2 1 T(0.017)DS(0.087)VKT(0.894)PES(0.002)EGNPLLEQLEK;T(0.082)DS(0.216)VKT(0.676)PES(0.026)EGNPLLEQLEK 133.15 3.4011e-05 28738000.0 28223.0 35272.0 23745.9 34600.0 36140.0 26190.0 43305.0 31268.0 26466.0 27905.0 True False 33000.596470341 38773.57105547288 24312.092312827244 32661.474174713494 29058.626433160716 24816.55029513999 39202.8368989505 30447.248131184493 26853.015181247152 32963.95560414155 1.0011115433669266 1.1762414535772951 0.7375356466556066 0.9908238734131152 0.881527289446714 0.7528389672998489 1.189263733082601 0.9236527465580964 0.814617502332559 1.0 15.008601752776507 -5.241666028706166 24.966711843094295 0.914603053768383 1.0886764882142108 0.22555909866096024 0.1313657174846952 1218.2441812407424 1538204.0028081853 0.0327868114232268 0.08647039569630852 5.732366790069528e-06 5.241666028706166 0.1740734344458278 TDSVKT(ph)PESEGNPLLEQLEK ddPTM_PC-9_Lapatinib_30min_R1 3 TDSVKTPESEGNPLLEQLEK 20 1 Q8WYK2;Q8WYK2-2 Q8WYK2 JDP2 Jun dimerization protein 2 1 T(0.048)DS(0.241)VKT(0.69)PES(0.021)EGNPLLEQLEK;T(0.105)DS(0.403)VKT(0.492)PESEGNPLLEQLEK;T(0.001)DS(0.008)VKT(0.991)PESEGNPLLEQLEK 112.42 2.9508000000000003e-05 43367000.0 37981.7 64023.9 55214.8 53874.5 82968.3 79179.6 87746.3 82068.4 63504.4 69639.6 True False 37440.073993009246 63875.65659316668 50675.2522792916 57836.61045006357 78088.26771595386 75793.27308466261 92289.37406805673 85881.59746942409 56351.86574102183 81676.71207106582 0.45839350095818177 0.7820547004584283 0.6204369763954227 0.7081162914557666 0.9560652692288873 0.9279667504088055 1.129934980582433 1.0514820600846377 0.6899379800204349 1.0 16.317637170664256 -6.199216688069227 2.7728822015269317 0.9732103831212555 0.6364925206060077 0.5941572843145723 0.12932832536290095 0.19825070586011942 3.00421567965997 0.04112919246349341 0.05397110657824951 6.320963927926039e-07 6.199216688069227 -0.3367178625152478 TDT(ph)NVLYER ddPTM_PC-9_Lapatinib_30min_R1 1 TDTNVLYER 9 0 A0A087WVD7;D6RDH4;Q9Y3D8-2;Q9Y3D8 A0A087WVD7 TAF9;AK6 Adenylate kinase isoenzyme 6 1 TDT(1)NVLYER 80.979 0.037537 4329800.0 5867.1 2414.6 55600.0 3486.4 9025.0 19443.0 5163.0 3932.5 35707.0 3720.9 True False 5783.434078105633 2409.0091420525832 51028.78262220661 3742.801486289459 8494.167243832688 18611.468213846703 5430.314877246984 4115.218306297061 31685.301648620654 4364.052607212404 1.325243895673356 0.552011939102487 11.692980634072125 0.8576435307181649 1.9463943284722338 4.264721324185646 1.2443284639310683 0.9429809117094284 7.2605223860626324 1.0 12.091452777640518 TDTAVQATGS(ph)VPSTPIAHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDTAVQATGSVPSTPIAHR 19 0 Q9NXR1;Q9NXR1-1;I3L533;I3L2R9;I3L2R3;I3L522 Q9NXR1 NDE1 Nuclear distribution protein nudE homolog 1 1 TDTAVQAT(0.003)GS(0.992)VPS(0.002)T(0.002)PIAHR 81.65 0.0011886 10997000.0 64564.0 61138.0 74187.0 88116.0 94085.0 75475.0 78179.0 97663.0 80339.0 53678.0 True False 75493.41000287337 67207.37659303422 75955.89943576424 83179.14619592644 75649.7196448235 71516.95813385602 70773.31915305505 95099.44973250212 81513.80588854446 63409.39648518581 1.190571337806546 1.059896171835285 1.1978650428175837 1.3117794965192484 1.1930364242229836 1.1278605711152663 1.116132987791323 1.4997690406140356 1.2855161917143991 1.0 15.952409025246858 TDTESELDLISR ddPTM_PC-9_AZD4547_30min_R2 1 TDTESELDLISR 12 0 V9GZ78;V9GYY3;A0A384N5Y3;F5H2F4;P11586;A0A494C1T2 V9GZ78 MTHFD1 C-1-tetrahydrofolate synthase, cytoplasmic;Methylenetetrahydrofolate dehydrogenase;Methenyltetrahydrofolate cyclohydrolase;Formyltetrahydrofolate synthetase;C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed 0 150.15 0.00078785 2938400.0 12553.0 11200.0 16593.0 23305.0 17005.0 15534.0 15635.0 19521.0 12437.0 14360.0 False True 16544.592881379696 14820.180972062752 16372.965978326409 17932.392308660743 14644.14927766627 14562.65652433903 17026.484710991615 16504.477997954065 13094.394429361271 13857.260770843819 1.1939295330423543 1.0694884953918853 1.1815441918200547 1.2940791549792545 1.0567852853341761 1.0509044150326874 1.228704936174396 1.1910346691808014 0.9449482582381905 1.0 13.758354480972178 -8.262855792170633 24.997083327619112 0.9724741087644252 1.1560306193401897 0.4896080623894954 0.07586669639757379 112.90383429303888 1992441.3108292914 0.06378284567599733 0.01988117338589419 5.45939110515009e-09 8.262855792170633 0.1835565105757645 TDTESELDLISR ddPTM_PC-9_Lapatinib_30min_R1 2 TDTESELDLISR 12 0 V9GZ78;V9GYY3;A0A384N5Y3;F5H2F4;P11586;A0A494C1T2 V9GZ78 MTHFD1 C-1-tetrahydrofolate synthase, cytoplasmic;Methylenetetrahydrofolate dehydrogenase;Methenyltetrahydrofolate cyclohydrolase;Formyltetrahydrofolate synthetase;C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed 0 ; 152.69 0.00029264 9571000.0 27727.0 31468.0 31838.0 30284.0 32987.0 30446.0 29749.0 31981.0 33939.0 27426.0 False True 27331.60789549095 31395.137779388155 29220.40253823408 32511.186384462486 31046.769514937263 29143.89555309244 31289.25765702506 33466.9540123805 30116.432426486033 32166.54755715213 0.849690438395023 0.9760182600761438 0.908409660263245 1.0107142001079854 0.9651881184878391 0.9060311959594304 0.9727266378659898 1.0404272933835335 0.9362656148589295 1.0 14.973273479063185 -3.96168144271209 1.5331333204946727 0.9694783524222563 1.986545733293237e-17 0.41590291861034223 0.04134966439705576 12.375183891300455 4.03828447183261 0.011488833144927274 33.0127912325686 0.00010922412073647518 3.96168144271209 -0.9694783524222563 TDTGIVTVEQS(ph)PSSSK ddPTM_PC-9_AZD4547_30min_R2 2 TDTGIVTVEQSPSSSK 16 0 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 TDTGIVTVEQS(0.918)PS(0.06)S(0.019)S(0.003)K;TDTGIVT(0.029)VEQS(0.693)PS(0.253)S(0.002)S(0.022)K 225.17 1.2613999999999999e-28 60280000.0 103059.0 95574.0 124971.0 137855.0 150976.0 136957.0 132900.0 145060.0 143408.0 152994.0 True False 135829.61823963275 126466.4264485647 123313.80288539926 106074.65958851873 130015.58843545687 128393.05713942963 144727.84253858574 122644.31014718564 150988.2541067654 147637.72662774913 0.9200197086623454 0.8565996601087923 0.835245879911984 0.7184793616876348 0.8806393284778465 0.8696493780560396 0.9802903759382565 0.8307111803232964 1.0226942500101226 1.0 17.17170190223102 -6.9963298278503725 2.078375470354887 0.9456476382286348 0.8341762076241162 0.3845801891800167 0.06852062668059065 0.37975118673612357 3.2963138657206876 0.030100981713015455 0.02353198225295467 1.0084866932008955e-07 6.9963298278503725 -0.1114714306045187 TDTGIVTVEQS(ph)PSSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TDTGIVTVEQSPSSSK 16 0 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 TDTGIVTVEQS(0.967)PS(0.031)S(0.001)S(0.001)K;TDTGIVTVEQS(0.993)PS(0.006)SSK;TDTGIVTVEQS(0.812)PS(0.152)S(0.036)SK;TDTGIVTVEQS(0.51)PS(0.25)S(0.079)S(0.161)K;TDTGIVTVEQS(0.834)PS(0.129)S(0.009)S(0.029)K 289.32 7.242799999999999e-97 30437100.0 143628.0 140474.0 145738.0 165846.0 194038.0 160365.0 164301.0 151395.0 143319.0 130977.2 True False 167941.3836176923 154419.33035967578 149212.94663444292 156554.1862999862 156017.64681343743 151955.17709355184 148737.2198437702 147421.0416662623 145414.76924209003 154722.32954505528 1.0854372740606109 0.9980416583290179 0.9643918048105137 1.0118396404728218 1.0083718831806041 0.9821153646041915 0.9613170915996181 0.9528103803745609 0.9398434580817574 1.0 17.239321896170033 TDTGIVTVEQS(ph)PSSSK ddPTM_PC-9_Lapatinib_30min_R1 2 TDTGIVTVEQSPSSSK 16 0 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 TDTGIVTVEQS(0.709)PS(0.289)S(0.001)SK;TDTGIVTVEQS(0.406)PS(0.406)S(0.062)S(0.127)K 169.15 8.3593e-06 63641000.0 108034.0 120342.0 138867.0 144054.0 157025.0 129380.0 113817.0 107058.0 137137.0 101244.0 True False 106493.41534899063 120063.35549279072 127449.89130212138 154648.21171005687 147789.09822302806 123846.71899951056 119709.88734914185 112032.30551444384 121691.18694336958 118743.89050084983 0.8968327961953417 1.011111855830018 1.0733174630252598 1.302367734944225 1.24460380740153 1.0429733982703238 1.0081351288408822 0.9434784816456898 1.0248206154446209 1.0 16.85749376159938 -6.993570833154556 24.88969516081592 0.9945635293377556 1.1129537645521135 0.19235936088090022 0.10751715518104336 280.54410092098266 1086082.9242096872 0.04288033152623108 0.037721757551167724 1.0149138212723302e-07 6.993570833154556 0.11839023521435788 TDTLEDLFPTTK ddPTM_PC-9_Lapatinib_30min_R1 2 TDTLEDLFPTTK 12 0 P13010 P13010 XRCC5 X-ray repair cross-complementing protein 5 0 ; 171.92 0.0039524 7498700.0 56705.0 54838.0 62829.0 53841.0 55471.0 58038.0 59057.0 44916.0 46779.0 52595.0 False True 55896.37630157655 54711.02598023668 57663.44214695359 57800.646748310835 52208.304840182056 55555.85003318594 62114.68249187972 47002.961333919615 41510.256415291835 61685.97567156771 0.9061439929098877 0.8869281126642548 0.9347901450723396 0.9370143881010592 0.8463561493807401 0.9006236738311449 1.0069498263688745 0.7619715960103427 0.6729285864959536 1.0 15.912654908974755 -7.782024798672907 24.99862528560014 0.7880875077653138 0.9139281422827544 0.22572122130561334 0.0860257884687607 297.0086895770785 360677.74825997505 0.044530389063646356 0.021429921968465885 1.6518674721613244e-08 7.782024798672907 0.12584063451744065 TDTPAPPTHALS(ph)QSPAEADGSVAFVPGEAQVAR ddPTM_PC-9_AZD4547_30min_R2 1 TDTPAPPTHALSQSPAEADGSVAFVPGEAQVAR 33 0 Q5SXM2 Q5SXM2 SNAPC4 snRNA-activating protein complex subunit 4 1 TDTPAPPTHALS(0.499)QS(0.499)PAEADGS(0.001)VAFVPGEAQVAR 81.446 1.2329999999999999e-08 3532700.0 6400.9 4670.7 7610.1 13725.0 10644.0 10514.0 7696.3 8915.9 8933.8 8099.8 True False 8436.253053009097 6180.412434483345 7509.1851016489945 10560.913299136188 9166.264328813859 9856.557917915574 8381.255790291314 7538.152521999822 9406.022429285817 7816.228467387242 1.0793252894549938 0.7907154275582855 0.9607171966608489 1.3511520733050453 1.172722159678362 1.2610375910890383 1.072288997853839 0.9644232577709728 1.2033965573718703 1.0 12.932256922381553 -5.549991730099726 24.550057382168784 1.1483617654115879 0.920194289713724 0.3489568104443811 0.12694924679599684 171.17741756289746 154995.51787555218 0.03470956618895192 0.06012069819717865 2.818436599843409e-06 5.549991730099726 -0.2281674756978639 TDTPPSSVPTSVISTPS(ph)TEEIQSETPGDAQGSPPELKRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDTPPSSVPTSVISTPSTEEIQSETPGDAQGSPPELKRPR 40 2 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 TDTPPSSVPTSVIS(0.008)T(0.008)PS(0.197)T(0.197)EEIQS(0.197)ET(0.197)PGDAQGS(0.197)PPELKRPR 61.438 1.1918e-05 9458100.0 13189.0 2549.8 8682.9 21213.0 15184.0 27912.0 19077.0 27909.0 22572.0 16405.0 True False 15421.63720537602 2802.9272929588547 8889.93326608162 20024.50438347392 12208.804199256027 26448.245583732234 17269.88845448053 27176.418322029836 22902.07279797139 19379.096638091454 0.7957872079064474 0.1446366332396235 0.458738270008294 1.033304325657464 0.6299986231173678 1.3647821711021193 0.891160655060408 1.4023573353059196 1.18179258949332 1.0 14.24221370024458 -6.154801315589362 1.069841849794087 1.1748426593033883 0.42299468803708057 0.5299050247443067 0.2587067884828234 0.37589114523425177 0.8906601632006318 0.10579918161033405 0.18114356439923135 7.001622383987837e-07 6.154801315589362 -0.7518479712663078 TDTPPSSVPTSVISTPSTEEIQS(ph)ETPGDAQGSPPELKRPR ddPTM_PC-9_Lapatinib_30min_R1 1 TDTPPSSVPTSVISTPSTEEIQSETPGDAQGSPPELKRPR 40 2 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 TDTPPSSVPTSVIS(0.008)T(0.008)PS(0.08)T(0.08)EEIQS(0.379)ET(0.379)PGDAQGS(0.065)PPELKRPR 58.919 2.254e-05 6905800.0 60593.0 19436.0 34975.0 31156.0 16026.0 24934.0 8107.6 8856.6 27345.0 13757.0 True False 59728.93270860466 19390.99713614428 32099.490507404236 33447.31617336921 15083.382188328278 23867.630943992892 8527.371857208525 9268.109968607892 24265.118144384374 16134.879119949757 3.7018518864980905 1.201806161173438 1.9894472260232337 2.0729821354542235 0.9348308144235571 1.4792568798660584 0.5285054690409778 0.574414589641918 1.50389215586884 1.0 13.977895148963874 -1.5228787452803376 0.5385002968549931 0.9982578091898009 94.07960503682301 0.6363812576650483 0.5351265427681269 86.43244341473819 0.8206401938006672 0.27402653180712305 9262.538658248677 0.029999999999999995 1.5228787452803376 93.08134722763322 TDTS(ph)PVLETAGTVAAMAATPSAR ddPTM_PC-9_AZD4547_30min_R2 1 TDTSPVLETAGTVAAMAATPSAR 23 0 Q8WWH5 Q8WWH5 TRUB1 Probable tRNA pseudouridine synthase 1 1 T(0.041)DT(0.195)S(0.763)PVLETAGTVAAMAATPSAR 88.28200000000001 0.00093536 0.0 9663.1 13185.0 13061.0 15656.0 19042.0 13651.0 13729.0 17167.0 12300.0 12246.0 True False 12735.764795033856 17446.793403272084 12887.802606094201 12046.751082788784 16398.34698884569 12797.400812009268 14950.85440340287 14514.234608415421 12950.152889052322 11817.2712673923 1.0777246715302187 1.4763808842582355 1.0905904006499239 1.0194190190107333 1.3876593519600475 1.0829404286691349 1.265169772708624 1.2282221741380281 1.0958666003365778 1.0 13.52860932001564 -8.492308601911589 3.2988635887621442 1.0009542616546288 1.2065246724131864 0.18442070865993276 0.13788237539209675 0.3523151362013486 8.941177786938452 0.12751613201130557 0.0338241841375219 3.2187807702697823e-09 8.492308601911589 0.20557041075855764 TDTS(ph)PVLETAGTVAAMAATPSAR ddPTM_PC-9_Lapatinib_30min_R1 2 TDTSPVLETAGTVAAMAATPSAR 23 0 Q8WWH5 Q8WWH5 TRUB1 Probable tRNA pseudouridine synthase 1 1 T(0.123)DT(0.069)S(0.808)PVLETAGTVAAMAATPSAR;T(0.042)DT(0.209)S(0.743)PVLET(0.005)AGTVAAMAATPSAR 121.0 4.5658e-05 0.0 13847.9 15442.2 16505.4 13466.9 18699.6 15305.6 15763.1 15497.5 18257.4 16101.8 True False 13650.42640660616 15406.444534665949 15148.389724686489 14457.300750261462 17599.7262928281 14651.015167096226 16579.23618855935 16217.570426405262 16201.059353054787 18884.974675700145 0.7228194181361847 0.8158043523611327 0.8021397955157636 0.7655451489095243 0.9319433356441928 0.7758027436461495 0.8779061912056648 0.8587552117436985 0.857880914921277 1.0 14.20495122870925 -14.52287874446124 0.050390761372619525 1.7147744529846352 0.4734266345488738 0.6364830751736914 0.04730913925091902 350.7097469424821 1.3014137671600636 33.46631516475624 7.366724875734123 3.0000000056581276e-15 14.52287874446124 -1.2413478184357614 TDTVLILCR ddPTM_PC-9_Lapatinib_30min_R1 2 TDTVLILCR 9 0 Q9HB71;Q9HB71-3 Q9HB71 CACYBP Calcyclin-binding protein 0 ; 148.99 0.0013625 11443700.0 54035.0 55617.0 57743.0 39577.0 54840.0 59500.0 49685.0 47796.0 55674.0 47225.0 False True 53264.45099119459 55488.22225359832 52995.593434425835 42487.6246050017 51614.41901958831 56955.32370127439 52257.446189427894 50016.776647876475 49403.40784678937 55387.77832664293 0.9616643346312563 1.0018134673386434 0.9568102392894428 0.7670938587649411 0.9318737919979083 1.0283012863485341 0.9434833417806674 0.9030291186786441 0.891955036640729 1.0 15.757280050901088 -10.764320768570979 4.192179779612315 1.0000440051469224 0.9320728979578885 0.08442977683774378 0.06738883000115697 3.0282528096921525e-05 5.4794791136149075e-06 0.06990526796433738 0.0169433268508588 1.7205972776888732e-11 10.764320768570979 -0.06797110718903387 TDVIS(ph)DTFPGK ddPTM_PC-9_AZD4547_30min_R2 1 TDVISDTFPGK 11 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 TDVIS(0.871)DT(0.129)FPGK 121.68 0.0017882000000000002 0.0 13426.0 13204.0 22594.0 22812.0 24074.0 28280.0 23608.0 20831.0 22994.0 22279.0 True False 17695.188721851642 17471.934781706834 22294.388797342668 17553.045841886673 20731.740647488255 26511.64712941339 25709.066265243997 17612.047598759327 24209.415896818628 21499.018991199842 0.8230695888540209 0.8126852108395547 1.0369956325201812 0.8164579904353604 0.9643110067475332 1.2331561333224255 1.1958250874501504 0.8192023834189103 1.1260707247492654 1.0 14.391983210116704 -6.5277286769884535 24.91588679075643 1.074180996500856 0.881129680767189 0.3784915306937774 0.12239774444164744 150.0088867905698 770641.9166268482 0.04144100507831531 0.041585976009559614 2.966684229815424e-07 6.5277286769884535 -0.19305131573366696 TDVISDT(ph)FPGK ddPTM_PC-9_AZD4547_30min_R2 1 TDVISDTFPGK 11 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 TDVIS(0.202)DT(0.798)FPGK 108.59 0.0028236999999999997 0.0 19417.0 18267.0 29328.0 37906.0 35313.0 33962.0 30074.0 30957.0 29069.0 32531.0 True False 25591.202101310384 24171.450519345566 28939.091557425232 29167.35734186203 30410.3994967497 31838.350771185913 32750.52773894223 26173.306971090824 30605.527994460317 31392.09959166578 0.8152115479432455 0.7699851502052061 0.9218590643458652 0.9291305048486023 0.9687277975132089 1.0142153976740889 1.043272930608219 0.8337545851198662 0.9749436448202946 1.0 14.938113903187078 -5.4199074349086045 2.409560390735031 0.9652673096001464 0.7889969116232262 0.6046903010537422 0.05494546199912649 0.21015935147519904 2.3411413775632814 0.01602767849806535 0.04270745512624211 3.802704381444233e-06 5.4199074349086045 -0.17627039797692023 TDVISDT(ph)FPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDVISDTFPGK 11 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 TDVIS(0.093)DT(0.907)FPGK 106.01 0.006082100000000001 1717800.0 18653.0 18873.0 26117.0 18954.0 23359.0 21116.0 23369.0 22864.0 19626.0 16952.0 True False 21810.584486456795 20746.586712688222 26739.728329274058 17892.0688296971 18781.971633984536 20008.639787406482 21155.319143091434 22263.84422641047 19912.99312125582 20025.263408041836 1.0891534379367016 1.0360206649944348 1.3352997053979223 0.8934748305239232 0.9379138367009938 0.9991698675669516 1.0564315041466963 1.1117878338354168 0.9943935675402437 1.0 14.289533599210968 -5.785744525527997 24.999675865863537 1.0035340961666726 1.141744547660004 0.3753529622563204 0.09080653337784952 267.6363848030233 275283.2092995525 0.026616803278878328 0.039499550493979324 1.637779664804521e-06 5.785744525527997 0.13821045149333155 TDYNAS(ph)VSVPDSSGPER ddPTM_PC-9_AZD4547_30min_R2 3 TDYNASVSVPDSSGPER 17 0 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 TDYNAS(0.946)VS(0.008)VPDS(0.009)S(0.037)GPER;TDYNAS(0.985)VS(0.008)VPDS(0.006)S(0.001)GPER;TDYNAS(0.937)VS(0.063)VPDSSGPER 172.5 1.4214e-24 4768600.0 28673.4 64404.0 36717.8 40800.0 34331.3 54173.0 52932.0 54207.0 27070.800000000003 24987.7 True False 37790.944756229765 85221.33351113665 36230.89798101567 31394.1903537163 29564.99159637422 50785.55374617084 57642.84545712876 45830.55370294018 28501.707221866458 24112.888228663953 1.5672508576266762 3.534264858816483 1.5025532253720877 1.3019672324610527 1.226107437483542 2.106158053924043 2.3905408970712356 1.9006662855285654 1.1820113356634459 1.0 14.5575168460689 -1.9759797297409862 0.058130721012528336 5.5867334246743e-15 5.306358306285206 0.16863040529817674 0.6571189789762921 676.8991623866531 3.2063310492145662 64.84400566925186 313.61076453721165 0.01056866836261242 1.9759797297409862 5.306358306285201 TDYNAS(ph)VSVPDSSGPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TDYNASVSVPDSSGPER 17 0 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 T(0.014)DYNAS(0.961)VS(0.022)VPDS(0.002)S(0.002)GPER 91.14 0.015208000000000001 0.0 6350.2 14244.0 9081.3 11991.0 13453.0 11102.0 11620.0 13801.0 6181.3 4351.0 True False 7425.163437832945 15658.050184683467 9297.83263302204 11319.183145346524 10816.981223168545 10519.791576045982 10519.269478485276 13438.738373368222 6271.689818629302 5139.801857502949 1.4446400160336696 3.046430702737354 1.8089865895217938 2.202260604428374 2.1045521837341252 2.0467309572818384 2.0466293779651292 2.614641331698556 1.2202201548828293 1.0 12.327497028379327 -8.384053450524402 5.455249238085133 1.0196098024400702 2.171254694909591 0.5180737856653742 0.4083668630892898 0.1621103398934077 6.156808617825491 0.36020693180929203 0.09370382765552043 4.129966695528039e-09 8.384053450524402 1.1516448924695208 TDYNAS(ph)VSVPDSSGPER ddPTM_PC-9_Lapatinib_30min_R1 2 TDYNASVSVPDSSGPER 17 0 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 T(0.185)DYNAS(0.77)VS(0.002)VPDS(0.016)S(0.028)GPER;TDYNAS(0.842)VS(0.009)VPDS(0.031)S(0.118)GPER 147.84 3.8896e-05 5867000.0 27523.0 56032.0 30593.0 37516.0 33999.0 42960.0 50097.0 55926.0 25626.4 22634.4 True False 27130.516972899964 55902.26134659581 28077.76163239507 40275.051789707286 31999.24566460583 41122.700944651224 52690.77753349644 58524.526127900666 22740.084974044657 26546.72588155779 1.0219910769390863 2.1058062525681005 1.057673242179402 1.517138195097975 1.2053933056519013 1.5490686545725576 1.9848314917848726 2.204585468995937 0.8566060114344407 1.0 14.696246317953051 -6.990987980476627 24.4357842935791 1.6340396174010265 1.4079542628375672 0.0 0.47608829038815564 544.2240889503568 1475634.3964833915 0.16238894648706753 0.14299537873265697 1.0209677395946621e-07 6.990987980476627 -0.22608535456345935 TDYNASVSVPDSSGPER ddPTM_PC-9_Lapatinib_30min_R1 4 TDYNASVSVPDSSGPER 17 0 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 ;;; 252.46 2.7168e-48 47967000.0 74942.0 84013.0 78419.0 82048.0 76886.0 85433.0 82982.0 71819.0 82736.0 88874.0 False True 73873.31333732027 83818.47306024349 71971.692526094 88082.08362410456 72363.71664369194 81779.22974405004 87278.40192595555 75155.97292814986 73417.40043129584 104235.75248283884 0.708713772172198 0.8041240271570274 0.6904703118821277 0.8450275603719195 0.6942312490678834 0.7845602664739625 0.8373173296784603 0.7210191430289082 0.7043399091245888 1.0 16.669490676072577 -10.768124254029335 4.780082083123919 1.0000598945693366 0.7572400174859433 0.6291098566982033 0.05653052552499697 3.434878979004781e-05 5.423532262152735e-06 0.05210404915384774 0.012633976587022625 1.7055943393098245e-11 10.768124254029335 -0.24281987708339337 TEAACLSAPHLAS(ph)PPATPK ddPTM_PC-9_AZD4547_30min_R2 2 TEAACLSAPHLASPPATPK 19 0 Q5TGY3 Q5TGY3 AHDC1 AT-hook DNA-binding motif-containing protein 1 1 TEAACLSAPHLAS(0.999)PPAT(0.001)PK;TEAACLSAPHLAS(0.998)PPAT(0.002)PK 120.33 2.5425e-05 50927000.0 183082.0 167853.0 250390.0 305520.0 248660.0 218129.0 211947.0 244560.0 201360.0 220630.0 True False 241298.2676578312 222108.19970568287 247069.66499808012 235087.08423694596 214137.8511840332 204489.35914751785 230809.87240425538 206768.871429724 212003.47851541283 212905.81085454594 1.1333568900225206 1.0432228167667243 1.160464639299462 1.1041835039324217 1.0057867858305145 0.9604686613613469 1.0840938134936169 0.9711753314755012 0.995761823805976 1.0 17.699855800350235 -6.257348547462558 6.212090516571529 1.0031459533540814 1.109504604151511 0.6194851706758393 0.04126442085310424 0.10324335491604626 19.549380883123554 0.012301014363668627 0.015040439728807961 5.529061906056545e-07 6.257348547462558 0.10635865079742968 TEAACLSAPHLAS(ph)PPATPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEAACLSAPHLASPPATPK 19 0 Q5TGY3 Q5TGY3 AHDC1 AT-hook DNA-binding motif-containing protein 1 1 TEAACLSAPHLAS(0.998)PPAT(0.002)PK 138.04 7.3343e-05 27597000.0 62012.0 66820.0 71639.0 100140.0 99952.0 74402.0 71893.0 79098.0 67549.0 65605.0 True False 72509.40680717092 73453.44800200437 73347.14545242043 94529.48045826024 80367.1231114357 70500.22814276458 65082.774579754114 77021.76131125845 68536.77633484712 77498.66717110563 0.9356213397461512 0.9478027259466281 0.9464310565558599 1.2197562088332834 1.0370129712553244 0.9096960078953419 0.8397921790843312 0.9938462701714051 0.8843607101465116 1.0 16.241883878553473 -6.763556158635324 24.99641854697073 0.9197952343393617 1.0207701677145107 0.2116064161060215 0.08811049987279877 91.12221953537086 1076022.7147498396 0.03225821311869122 0.02986662735273054 1.7236291940617992e-07 6.763556158635324 0.10097493337514896 TEAACLSAPHLAS(ph)PPATPK ddPTM_PC-9_Lapatinib_30min_R1 2 TEAACLSAPHLASPPATPK 19 0 Q5TGY3 Q5TGY3 AHDC1 AT-hook DNA-binding motif-containing protein 1 1 TEAACLSAPHLAS(0.994)PPAT(0.006)PK;TEAACLSAPHLAS(0.993)PPAT(0.007)PK 96.579 0.00036866 46641000.0 227748.0 196526.0 222908.0 205804.0 262370.0 235890.0 224051.0 214559.0 225405.0 176282.0 True False 224500.27175613208 196070.9561215215 204581.36468976282 220939.51270201767 246937.9124392666 225801.53458644752 235651.26449003757 224528.19442613915 200017.51528012278 206752.10881900013 1.0858427178252845 0.948338361535991 0.9895007400812648 1.0686203587671157 1.1943670797353119 1.0921365488181023 1.1397768363095007 1.0859777716835817 0.9674267238320016 1.0 17.657542519031416 -4.4361414272138004 22.472993491080697 1.0606762900378575 3.325003850654185 0.0090856040407723 0.07475694457201269 4193.333341670965 1307477.288710776 0.019591078626829187 98837.99830714235 3.663182643409947e-05 4.4361414272138004 2.2643275606163273 TEAELSQDLET(ph)SPTAKPQIK ddPTM_PC-9_AZD4547_30min_R2 1 TEAELSQDLETSPTAKPQIK 20 1 Q5VT06;H0Y7F7 Q5VT06 CEP350 Centrosome-associated protein 350 1 TEAELS(0.001)QDLET(0.498)S(0.498)PT(0.002)AKPQIK 99.999 0.00024066 5791800.0 16044.0 17073.0 14570.0 20906.0 15842.0 16334.0 14465.0 19972.0 12920.0 15917.0 True False 21145.658264068814 22591.51336928816 14376.792280131112 16086.444694480226 13642.611752824987 15312.632397872654 15752.356977581943 16885.78631090305 13602.924823297237 15359.750674757735 1.376692806532313 1.4708255262512253 0.9360042740640302 1.0473115765424983 0.8882052867723498 0.9969323540542545 1.0255607210779416 1.0993528911021457 0.8856214603569268 1.0 13.906867177430787 -5.260958759198214 24.99999997043984 0.9890831549016864 1.4237592006091597 0.8720706118902093 0.06722343933090327 12.431838252167053 646611.4670149415 0.016902382848463 0.03953334136351472 5.483290320232551e-06 5.260958759198214 0.4346760457074733 TEAELSQDLET(ph)SPTAKPQIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEAELSQDLETSPTAKPQIK 20 1 Q5VT06;H0Y7F7 Q5VT06 CEP350 Centrosome-associated protein 350 1 TEAELSQDLET(0.499)S(0.499)PT(0.002)AKPQIK 67.895 0.0038445 5133600.0 30415.0 27379.0 29896.0 32469.0 29805.0 32019.0 33319.0 33325.0 29610.0 28936.0 True False 35563.65877636752 30097.00617849263 30608.834021211376 30649.86719591828 23964.924206982738 30339.867273771964 30162.78311132967 32450.25406075617 30042.99023338353 34181.86774275004 1.0404246790730316 0.880496244529417 0.8954699097068357 0.8966703465880417 0.7011004895151082 0.887601213079032 0.8824205669020877 0.9493411625419111 0.8789159931073585 1.0 15.060943609494572 -10.03866968180688 11.567366475416186 0.9999999963513722 0.8861888749409089 0.146351789427015 0.07895068060183298 0.0 0.0 0.07822539398185435 0.018972444823102452 9.148087674432846e-11 10.03866968180688 -0.11381112141046323 TEAELSQDLET(ph)SPTAKPQIK ddPTM_PC-9_Lapatinib_30min_R1 2 TEAELSQDLETSPTAKPQIK 20 1 Q5VT06;H0Y7F7 Q5VT06 CEP350 Centrosome-associated protein 350 1 TEAELS(0.002)QDLET(0.578)S(0.397)PT(0.022)AKPQIK;T(0.002)EAELS(0.033)QDLET(0.482)S(0.482)PT(0.002)AKPQIK 73.383 0.0020685 11592600.0 47342.0 41443.0 49079.0 44104.0 47476.0 47118.0 38500.5 40559.0 50992.0 34400.1 True False 46666.894398540484 41347.04127975034 45043.91407041868 47347.55528663102 44683.55502140729 45102.87297742267 40493.86750560672 42443.5192079091 45248.74399043507 40346.11144974801 1.1566639936704968 1.0248085823896316 1.1164375562319528 1.17353453865321 1.1075058640300852 1.117898884347239 1.0036622130497692 1.0519853756110662 1.1215143755995767 1.0 15.300142013089653 -7.235124616969715 24.433922680614245 1.0486226042625746 1.114219772888316 0.34744791697357635 0.0480497239313393 722.0358216518895 670429.1267127012 0.01860706874275933 0.014407218076633138 5.8193621235005685e-08 7.235124616969715 0.0655971686257415 TEAELSQDLETS(ph)PTAKPQIK ddPTM_PC-9_AZD4547_30min_R2 1 TEAELSQDLETSPTAKPQIK 20 1 Q5VT06;H0Y7F7 Q5VT06 CEP350 Centrosome-associated protein 350 1 TEAELSQDLET(0.411)S(0.587)PT(0.002)AKPQIK 92.792 0.00029507 7263700.0 17782.0 15879.0 21269.0 25382.0 23644.0 20601.0 21404.0 20133.0 16995.0 19453.0 True False 23436.306111423062 21011.57621923076 20986.959163082272 19530.572047990863 20361.438725147964 19312.81621333258 23308.914534957763 17021.907460315004 17893.321004019854 18771.95639103238 1.2484743530844182 1.1193066818154487 1.1179953077830518 1.0404121787391793 1.0846732381540636 1.0288121179824694 1.2416880824468965 0.906773226281657 0.9531942559043945 1.0 14.196291393519932 -1.5228787452803376 0.23645596236612565 0.9835345571317661 2.3214985785983484 0.40703880924465596 0.08216995985253485 56.078975340190766 0.7440579686512577 0.1188800407473356 29.300535750726002 0.029999999999999995 1.5228787452803376 1.3379640214665822 TEAELSQDLETS(ph)PTAKPQIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEAELSQDLETSPTAKPQIK 20 1 Q5VT06;H0Y7F7 Q5VT06 CEP350 Centrosome-associated protein 350 1 TEAELSQDLET(0.206)S(0.794)PTAKPQIK 109.44 3.9919e-05 5201000.0 15474.0 22404.0 18426.0 20056.0 23456.0 23179.0 21450.0 23042.0 20429.0 18438.0 True False 18093.44257456884 24628.1210571222 18865.345720994137 18932.327342429304 18859.965180304862 21963.452435702548 19418.100715448298 22437.171915017072 20727.735477129063 21780.6634448723 0.8307112692119797 1.1307332818147124 0.8661511054859763 0.8692263846942841 0.865904072575207 1.0083922600104855 0.8915293496268495 1.0301418031551894 0.9516576723933025 1.0 14.410760279152916 -7.761181904081175 24.99997881908791 0.9931748004435351 0.9280134730253655 0.12456335696978649 0.08522450190861469 16.279593281251632 1581239.755564391 0.042456080133744606 0.022533254137976935 1.7330779466624254e-08 7.761181904081175 -0.0651613274181696 TEAELSQDLETS(ph)PTAKPQIK ddPTM_PC-9_Lapatinib_30min_R1 1 TEAELSQDLETSPTAKPQIK 20 1 Q5VT06;H0Y7F7 Q5VT06 CEP350 Centrosome-associated protein 350 1 TEAELSQDLET(0.303)S(0.577)PT(0.12)AKPQIK 90.59200000000001 0.00031595 5518000.0 46617.0 37784.0 50207.0 39513.0 46850.0 44156.0 42373.0 38624.0 47798.0 37086.0 True False 45952.23303148922 37696.513469442056 46079.17426462462 42418.91783150399 44094.37511064393 42267.550812663416 44566.866607318654 40418.61204384432 42414.48590474617 43496.26568601124 1.0564638666502315 0.8666609161706856 1.0593823064549668 0.9752312563500426 1.013750822402785 0.9717512560223535 1.0246136284212493 0.9292432673557831 0.9751293642292382 1.0 15.40860392516522 -9.888942468045173 17.862184687821813 0.9999999997800326 0.9840386326381182 0.004997439840235818 0.05526229560345291 0.0 0.0 0.049311843318852217 0.011959878741031545 1.291390335629459e-10 9.888942468045173 -0.01596136714191443 TEAHQDVVGR ddPTM_PC-9_AZD4547_30min_R2 1 TEAHQDVVGR 10 0 A0A087WV29;Q9H0A0-2;Q9H0A0;E9PMU0 A0A087WV29 NAT10 N-acetyltransferase 10 0 88.134 0.0096139 0.0 8272.0 11816.0 11725.0 17130.0 10570.0 11093.0 9459.1 13849.0 8583.1 11365.0 False True 10902.323931711362 15635.290925526202 11569.518839021095 13180.94315586177 9102.537951480885 10399.352956385535 10300.94157529522 11708.955268360512 9036.785143254057 10967.114809236775 0.9940922586612438 1.4256521607996457 1.0549282140528848 1.20186059735241 0.8299847416400258 0.9482305179870045 0.9392572025068538 1.0676422625300632 0.8239892898397538 1.0 13.420896415966975 -6.248198156875083 24.75778758121189 0.9391221013262937 1.1792985961451157 0.4561406666891682 0.12507660757129765 601.7015180808617 1125031.2417060696 0.03497953053363071 0.044884512897912086 5.64679268083137e-07 6.248198156875083 0.24017649481882197 TEAPAPASSTPQEPWPGPT(ph)APSPTSRPPWAVDPAFAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAER 38 1 Q9NR12-2;Q9NR12 Q9NR12-2 PDLIM7 PDZ and LIM domain protein 7 1 TEAPAPASSTPQEPWPGPT(0.456)APS(0.456)PT(0.044)S(0.044)RPPWAVDPAFAER;TEAPAPASSTPQEPWPGPT(0.69)APS(0.254)PT(0.022)S(0.034)RPPWAVDPAFAER 83.368 1.7069e-10 6412300.0 14936.599999999999 14154.9 16467.0 20175.5 22219.5 20622.8 21336.0 20830.0 23041.8 16179.4 True False 17465.071368702655 15560.10492552485 16859.63573144527 19045.132144853535 17865.748479015354 19541.304063635474 19314.89962073681 20283.23457120934 23378.742734197105 19112.597143940075 0.9137989587270827 0.8141282321988568 0.8821216501594531 0.996470129173003 0.9347629913645696 1.0224305946735934 1.010584771670389 1.061249521373417 1.2232111919760562 1.0 14.222236213966108 -6.602153612066245 0.6713047514217054 1.100715161610758 0.8558439344603306 0.6184895731877215 0.06546597981798147 0.4940495180724157 0.4946303014384524 0.04708142473489536 0.05843653246694706 2.499461133792792e-07 6.602153612066245 -0.24487122715042742 TEAPAPASSTPQEPWPGPTAPS(ph)PTSRPPWAVDPAFAER ddPTM_PC-9_AZD4547_30min_R2 3 TEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAER 38 1 Q9NR12-2;Q9NR12 Q9NR12-2 PDLIM7 PDZ and LIM domain protein 7 1 TEAPAPASSTPQEPWPGPT(0.012)APS(0.936)PT(0.038)S(0.014)RPPWAVDPAFAER;TEAPAPASSTPQEPWPGPT(0.298)APS(0.52)PT(0.091)S(0.091)RPPWAVDPAFAER;TEAPAPASSTPQEPWPGPT(0.052)APS(0.763)PT(0.092)S(0.092)RPPWAVDPAFAER 101.85 1.2074e-20 12566900.0 29534.9 30904.6 39179.6 60033.0 47118.9 43175.5 32814.5 45031.8 38934.1 42300.0 True False 38926.38383591661 40893.907577608064 38660.052904504126 46193.31935060417 40577.254066417445 40475.72915968838 35734.92692989027 38073.17003781914 40992.07704045948 40819.08987511797 0.9536318412538861 1.0018329096194696 0.9471071751668347 1.131659708531673 0.9940754237921424 0.9915882319649931 0.8754464403595916 0.9327295183283187 1.004237898636906 1.0 15.31695639515644 -7.019613582502981 23.464385283060643 0.9455004031191437 1.0075592516796712 0.15054240753104042 0.0580250805997399 586.0362563044068 701093.001713057 0.02223689702331924 0.017514455240534597 9.558426775628041e-08 7.019613582502981 0.06205884856052746 TEAPAPASSTPQEPWPGPTAPS(ph)PTSRPPWAVDPAFAER ddPTM_PC-9_Lapatinib_30min_R1 2 TEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAER 38 1 Q9NR12-2;Q9NR12 Q9NR12-2 PDLIM7 PDZ and LIM domain protein 7 1 TEAPAPASSTPQEPWPGPT(0.039)APS(0.887)PT(0.037)S(0.037)RPPWAVDPAFAER;TEAPAPASSTPQEPWPGPT(0.123)APS(0.855)PT(0.011)S(0.011)RPPWAVDPAFAER 114.13 4.5144999999999997e-32 6795700.0 30793.0 28965.0 30929.0 27009.0 29772.0 35427.0 32862.0 30537.0 41866.0 30518.0 True False 30353.886173255396 28897.93332210429 28386.137009392598 28995.33195938276 28020.869494004088 33911.86979437058 34563.4335649991 31955.860500799343 37150.6102114754 35792.995637321124 0.8480398366435022 0.8073628040222652 0.7930640200395677 0.8100839687514032 0.7828590201817841 0.9474443027342169 0.9656479696535941 0.8927964796408148 1.0379296158363092 1.0 15.12738967240265 -6.802230318586195 6.601561339447183 0.96294874716286 0.807474096214783 0.8152138894482465 0.03816960988148838 0.08059099782673294 9.166095196860573 0.01294721513266783 0.01156834829252795 1.5767748398547238e-07 6.802230318586195 -0.155474650948077 TEAPGT(ph)PEGPEPERPSPGDGNPR ddPTM_PC-9_AZD4547_30min_R2 2 TEAPGTPEGPEPERPSPGDGNPR 23 1 A0A0G2JNW7;Q9Y666-2;Q9Y666 A0A0G2JNW7 SLC12A7 Solute carrier family 12 member 7 1 T(0.081)EAPGT(0.918)PEGPEPERPS(0.001)PGDGNPR;T(0.394)EAPGT(0.605)PEGPEPERPS(0.001)PGDGNPR 71.42699999999999 0.00061151 34200000.0 30202.0 53888.0 50296.0 43005.0 36812.0 24770.0 54231.0 54791.0 45290.0 27268.0 True False 39805.607759374616 71306.24216272465 49629.04217717743 33090.8616706267 31701.289221373172 23221.127984284645 59057.45394063229 46324.30992192512 47683.936938632454 26313.355619733262 1.5127530040115091 2.7098878300892086 1.8860780393952854 1.2575690515811961 1.2047604144261752 0.8824844812597884 2.244390825484194 1.7604865981891333 1.8121572036548879 1.0 14.683507619967026 -5.552405946958507 6.94764343466776 1.4870339981351743 2.1575580174650484 0.25025416875271433 0.47015623626089126 0.23023095951733677 37.65215159990262 0.13067877557281532 0.23175476392651082 2.8028125474122136e-06 5.552405946958507 0.670524019329874 TEAPGT(ph)PEGPEPERPSPGDGNPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEAPGTPEGPEPERPSPGDGNPR 23 1 A0A0G2JNW7;Q9Y666-2;Q9Y666 A0A0G2JNW7 SLC12A7 Solute carrier family 12 member 7 1 T(0.206)EAPGT(0.794)PEGPEPERPSPGDGNPR 79.426 0.00016116 5416800.0 14820.0 19031.0 16835.0 11686.0 29244.0 12260.0 13425.0 11964.0 9194.7 12999.0 True False 17328.733291657627 20920.271908502607 17236.410247093045 11031.271306523176 23513.848129810536 11617.06401750348 12153.286811416945 11649.957676905828 9329.155092836592 15355.615799972622 1.1284948462756228 1.3623857343799854 1.122482515297353 0.718386774598961 1.5312865622655432 0.7565352095826853 0.7914555150200238 0.7586773352929681 0.6075402780560077 1.0 13.906478748831823 -6.822404850579858 24.999062151808822 0.7682957191149097 1.1551329058131998 0.4520315229492574 0.21383752019538407 66.10417159635142 27105.46800488078 0.07398138222910414 0.06524546825147842 1.5052032571144205e-07 6.822404850579858 0.38683718669829015 TEAPGTPEGPEPERPS(ph)PGDGNPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEAPGTPEGPEPERPSPGDGNPR 23 1 A0A0G2JNW7;Q9Y666-2;Q9Y666 A0A0G2JNW7 SLC12A7 Solute carrier family 12 member 7 1 T(0.044)EAPGT(0.461)PEGPEPERPS(0.495)PGDGNPR 54.833999999999996 0.0046998000000000005 11874000.0 26231.0 37439.0 41309.0 31068.0 48418.0 19044.0 27293.0 22349.0 20366.0 25207.0 True False 30671.390214134386 41155.696494268814 42293.96322525488 29327.360683815008 38930.8404715212 18045.29911495403 24707.60945579164 21762.362430722875 20663.814221313358 29776.829561497805 1.030042172582177 1.3821382968012206 1.4203648893481275 0.9849054152405812 1.3074206033626818 0.6060181483621432 0.8297595754700227 0.7308488764989998 0.6939561573752027 1.0 14.861902533086683 -6.755748393594887 24.99995120296178 0.7588972799667517 1.2312235390600645 0.665612855676307 0.160321728650512 80.18677322754209 352252.49887688854 0.05242660425124547 0.051059773475738014 1.754896898411501e-07 6.755748393594887 0.47232625909331283 TEAPGTPEGPEPERPS(ph)PGDGNPR ddPTM_PC-9_Lapatinib_30min_R1 3 TEAPGTPEGPEPERPSPGDGNPR 23 1 A0A0G2JNW7;Q9Y666-2;Q9Y666 A0A0G2JNW7 SLC12A7 Solute carrier family 12 member 7 1 T(0.001)EAPGT(0.003)PEGPEPERPS(0.996)PGDGNPR;T(0.021)EAPGT(0.337)PEGPEPERPS(0.642)PGDGNPR;T(0.002)EAPGT(0.016)PEGPEPERPS(0.981)PGDGNPR 53.585 0.0064554 23158700.0 42162.3 72841.0 31201.0 30506.6 49768.0 29550.600000000002 23453.4 20130.1 38511.0 21718.199999999997 True False 41561.05787038112 72672.34113983785 28635.774219342962 32750.15713103432 46840.74408765266 28286.78972381312 24667.70229363244 21065.417934543042 34173.485641191655 25472.161932317562 1.631626635415305 2.8530103307656627 1.1241988134117347 1.2857234975992702 1.8388994311560147 1.110498190101584 0.9684180855624794 0.826997645135747 1.341601303100793 1.0 14.63663379211278 -5.543094686624715 0.6476496524321984 1.033613980568436 2.397496963677187 0.4048325772340887 0.4369842035624923 1.4532238516969742 0.8684501007782601 0.23663981892412497 1.2909619381051387 2.863553578407223e-06 5.543094686624715 1.363882983108751 TEAQDLCRAS(ph)PEPPGPESSSR ddPTM_PC-9_AZD4547_30min_R2 3 TEAQDLCRASPEPPGPESSSR 21 1 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 T(0.001)EAQDLCRAS(0.999)PEPPGPESSSR;TEAQDLCRAS(1)PEPPGPESSSR;T(0.001)EAQDLCRAS(0.997)PEPPGPESS(0.001)S(0.001)R 124.98 1.4369e-05 462856500.0 87259.3 78986.0 121899.0 249671.0 190377.0 119163.0 89390.0 141353.0 91818.0 144321.0 True False 115005.9422938082 104516.67984458474 120282.53961260823 192113.2083284974 163946.4396962232 111711.7187723581 97345.53682862416 119510.1418188005 96671.31202983794 139268.36571789338 0.8257865431318987 0.7504696368470152 0.8636745250264266 1.3794461314901065 1.177197986428006 0.8021327614244075 0.698978094033289 0.8581284141790262 0.6941369027454415 1.0 17.08750806687099 -6.878847907127501 11.570468563193266 0.7938441696818358 0.9989980950172848 0.19921633620093848 0.18765835887691729 0.6961065268271078 67.05880253052896 0.07348711870970187 0.06481667679664457 1.321758441911802e-07 6.878847907127501 0.20515392533544896 TEAQDLCRAS(ph)PEPPGPESSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TEAQDLCRASPEPPGPESSSR 21 1 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 TEAQDLCRAS(0.999)PEPPGPESSSR;TEAQDLCRAS(1)PEPPGPESSSR;T(0.003)EAQDLCRAS(0.997)PEPPGPESSSR;TEAQDLCRAS(0.999)PEPPGPESSSR;T(0.07)EAQDLCRAS(0.873)PEPPGPES(0.001)S(0.031)S(0.025)R 116.79 1.4634e-05 360439000.0 145853.0 93843.8 229799.0 250147.0 320420.0 295507.0 210760.0 301563.0 248676.0 175896.0 True False 170543.03217193927 103159.9922719318 235278.2796775606 236132.07457751656 257636.00115421624 280010.0927096575 190795.28702973816 293647.2907824102 252312.416051228 207784.55240803014 0.8207685807029627 0.49647575373820246 1.1323184372991335 1.1364274766384939 1.2399189360732261 1.3475982187539948 0.9182361480610461 1.4132296524419674 1.2142982388592474 1.0 17.664728876548367 -5.339066232704104 5.895475385107631 1.1912207080453652 0.6608836244094797 0.6346859492584762 0.15665815929277033 0.11734050023735217 6.898568693372896 0.03935001503480601 0.0840110253230284 4.580720224551969e-06 5.339066232704104 -0.5303370836358855 TEAQDLCRAS(ph)PEPPGPESSSR ddPTM_PC-9_Lapatinib_30min_R1 6 TEAQDLCRASPEPPGPESSSR 21 1 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 TEAQDLCRAS(1)PEPPGPESSSR;T(0.003)EAQDLCRAS(0.926)PEPPGPES(0.051)S(0.016)S(0.003)R;TEAQDLCRAS(1)PEPPGPESSSR;TEAQDLCRAS(0.987)PEPPGPES(0.011)S(0.002)SR;TEAQDLCRAS(1)PEPPGPESSSR;T(0.001)EAQDLCRAS(0.999)PEPPGPESSSR 113.54 2.6201e-05 809232000.0 446493.3 302344.5 487783.4 386986.5 354490.89999999997 361388.7 263526.6 255901.4 388054.7 287850.5 True False 440126.22366515617 301644.43988624134 447679.7317503757 415446.77815912064 333640.4422179245 345932.94773920573 277170.7179024431 267791.51325799036 344347.89328885125 337605.0753883182 1.3036718217548022 0.8934831312570926 1.3260456207165963 1.2305702977991897 0.988256594881361 1.0246674974933616 0.8209909687632431 0.7932093821456111 1.0199725015768124 1.0 18.364977067411168 -6.593666139765122 1.9898510971333614 0.902228649288197 1.174183540526659 0.4436732486587691 0.13403180933368533 0.3052585277043095 2.460827945629548 0.050474136307703636 0.052038622199718124 2.5487888596831964e-07 6.593666139765122 0.27195489123846195 TEARSS(ph)DEENGPPSSPDLDR ddPTM_PC-9_Lapatinib_30min_R1 1 TEARSSDEENGPPSSPDLDR 20 1 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 T(0.043)EARS(0.198)S(0.759)DEENGPPSSPDLDR 85.51 0.00036418 7255900.0 10912.0 12429.0 15511.0 12127.0 12986.0 11734.0 10517.0 12158.0 13465.0 9416.0 True False 10756.392878984285 12400.22141413549 14235.745454191483 13018.860034486084 12222.18901145831 11232.164173289983 11061.518799923786 12722.905064961129 11948.429907264048 11043.54305396866 0.9739983650553901 1.1228481071280187 1.2890560017399177 1.1788662362128035 1.1067271573741984 1.017079764926849 1.0016277154774766 1.1520673214008945 1.0819380925915985 1.0 13.430915479776438 -6.531689082203896 6.090615283274947 1.0571384373858903 1.1497873584612326 0.20545777987288683 0.08334267956653621 0.2668124147752623 39.58892655837076 0.029169451029739325 0.030255637026896258 2.939753511481381e-07 6.531689082203896 0.09264892107534228 TEATQGLDYVPS(ph)AGTISPTSSLEEDKGFK ddPTM_PC-9_AZD4547_30min_R2 1 TEATQGLDYVPSAGTISPTSSLEEDKGFK 29 1 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 TEATQGLDY(0.006)VPS(0.988)AGT(0.005)IS(0.001)PTSSLEEDKGFK 109.4 7.1332e-12 4840900.0 30813.0 26597.0 33637.0 42389.0 38378.0 37251.0 35318.0 34363.0 30897.0 39026.0 True False 40610.8930497851 35193.96011731725 33190.95140197463 32616.870953521575 33049.8771525008 34921.68908125101 38461.23357996813 29052.987933184522 32530.152342524365 37659.7116185899 1.0783644192787292 0.9345254810699218 0.8813384376950628 0.8660945490995466 0.8775924119447172 0.9272957115267095 1.021283274006341 0.7714607118457898 0.8637918599054423 1.0 15.200734332023545 -4.771512664545336 2.9846257743584292 0.896333458299225 1.1109879346758837 0.37987062203038524 0.06745595026550516 0.42055400712987645 5.295273115930295 0.01739467401761003 0.2218727427686582 1.69233889309526e-05 4.771512664545336 0.2146544763766588 TEATQGLDYVPSAGT(ph)ISPTSSLEEDKGFK ddPTM_PC-9_Lapatinib_30min_R1 1 TEATQGLDYVPSAGTISPTSSLEEDKGFK 29 1 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 TEATQGLDYVPS(0.007)AGT(0.41)IS(0.41)PT(0.13)S(0.042)S(0.001)LEEDKGFK 98.98 6.9712e-11 4514200.0 32085.0 32850.0 40631.0 37389.0 36811.0 33803.0 32561.0 30298.0 36599.0 30643.0 True False 31627.462016331614 32773.937843298 37290.476020195616 40138.71178604769 34645.84935321054 32357.32448864168 34246.84925780342 31705.755688286947 32476.835215444244 35939.60172076907 0.8800170425387458 0.9119171129923327 1.037587347514925 1.1168379688206729 0.9640020393767781 0.900325071491896 0.9529000772986467 0.8821955216594559 0.9036503928944841 1.0 15.13328680067735 -6.531536534824362 19.25453649760534 0.923146034743489 0.9918387980682244 0.14102676187208585 0.06780778656694611 22.831666240357098 50769.364943015025 0.02425881227565616 0.02435897532444515 2.940786291041426e-07 6.531536534824362 0.0686927633247354 TEATQGLDYVPSAGTISPT(ph)SSLEEDKGFK ddPTM_PC-9_AZD4547_30min_R2 1 TEATQGLDYVPSAGTISPTSSLEEDKGFK 29 1 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 TEATQGLDYVPS(0.003)AGT(0.12)IS(0.117)PT(0.571)S(0.187)S(0.003)LEEDKGFK 124.73 1.2115e-12 5419900.0 43621.0 41472.0 48480.0 59942.0 48956.0 50503.0 47861.0 51765.0 46470.0 52740.0 True False 57491.57062683528 54877.012970838055 47837.12352373073 46123.29799466819 42159.30444207172 47345.03942633539 52120.53628095745 43765.908691362696 48926.30932961472 50893.58865280663 1.1296426946631672 1.078269668606121 0.939944004540003 0.9062693202736967 0.8283814436761429 0.9302751226548542 1.0241080981048711 0.8599493541304664 0.9613452425881659 1.0 15.635196303013688 -5.200938449120365 2.916427509588114 0.9233589310431639 1.1225515781644742 0.6108170482922763 0.05567477287743443 0.17387569711340065 2.8522750000317116 0.015079521315158145 0.05057614992295476 6.2959540665980675e-06 5.200938449120365 0.19919264712131024 TEDEEFLIQHLLQAPS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 2 TEDEEFLIQHLLQAPSPPR 19 0 Q9ULL5;Q9ULL5-2 Q9ULL5 PRR12 Proline-rich protein 12 1 TEDEEFLIQHLLQAPS(1)PPR;TEDEEFLIQHLLQAPS(1)PPR 165.19 9.6512e-08 34084700.0 36568.6 34976.0 42612.0 45858.0 46732.0 48393.0 40185.0 58960.0 45931.0 57672.0 True False 48196.65412586805 46281.3080070417 42046.937037813834 35286.14659903731 40244.06845303732 45366.978059890454 43761.38715133984 49849.0867660146 48358.81889000505 55652.92083399062 0.8660220057386715 0.8316060920701019 0.7555207598759707 0.6340394371086795 0.7231258997723229 0.8151769463316665 0.7863268718972986 0.8957137562413209 0.8689358647366696 1.0 15.764169786112788 -8.207899327849464 0.901612564433884 0.9893292589546506 0.7621786498404428 0.5622575717650505 0.06346228272700273 0.4399198179523746 0.7390819482107608 0.0663572629045849 0.024362794816445068 6.1958468199809055e-09 8.207899327849464 -0.2271506091142078 TEDEEFLIQHLLQAPS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TEDEEFLIQHLLQAPSPPR 19 0 Q9ULL5;Q9ULL5-2 Q9ULL5 PRR12 Proline-rich protein 12 1 TEDEEFLIQHLLQAPS(1)PPR;TEDEEFLIQHLLQAPS(1)PPR;TEDEEFLIQHLLQAPS(1)PPR 240.21 1.6075e-118 20333200.0 61212.5 65517.7 65459.3 66404.8 78023.5 59124.700000000004 71875.9 56855.4 60944.2 52738.9 True False 71574.56724801575 72021.86426460522 67020.0979677777 62684.35434326632 62735.355271381144 56024.096648914245 65067.2944155473 55363.00599327584 61835.39362990111 62300.0450890973 1.1488686267506654 1.1560483489474915 1.0757632337493512 1.0061686834033492 1.0069873172910435 0.8992625377524588 1.044418095083117 0.8886511384397784 0.992541715523132 1.0 15.926945586936665 -5.630828622924537 1.3423700826912126 0.9646599222113876 1.1650974653824595 0.7212373406666025 0.04484152694176725 0.23286313253901686 0.8046877848128356 0.013941042939222006 0.04140987403370899 2.339760350044632e-06 5.630828622924537 0.20043754317107187 TEDEEFLIQHLLQAPS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 2 TEDEEFLIQHLLQAPSPPR 19 0 Q9ULL5;Q9ULL5-2 Q9ULL5 PRR12 Proline-rich protein 12 1 TEDEEFLIQHLLQAPS(1)PPR;TEDEEFLIQHLLQAPS(1)PPR 178.72 7.2016000000000004e-09 20275400.0 37432.9 48774.0 40575.0 45199.3 49716.0 46439.0 42736.0 44629.0 53003.0 41565.0 True False 36899.099981646854 48661.06679966565 37239.08012402935 48523.407302444706 46791.80262541674 44452.91222459636 44948.66097114606 46702.62626617457 47033.24399366629 48749.454868118875 0.7569130789558448 0.9981868911418119 0.7638871085794013 0.9953630750069782 0.9598425818709534 0.9118648063830481 0.9220341251557573 0.958013302764481 0.9647952807042577 1.0 15.573098465827929 -2.860522685608703 0.46263854622859124 0.9576287754628362 7.974365322422463e-42 0.3304877551844494 0.07047073391448687 34.59781568540799 1.3603395425517515 0.0415109903617232 26.432160309602438 0.0013787239326926283 2.860522685608703 -0.9576287754628362 TEDEEFLIQHLLQAPSPPR ddPTM_PC-9_AZD4547_30min_R2 1 TEDEEFLIQHLLQAPSPPR 19 0 Q9ULL5;Q9ULL5-2 Q9ULL5 PRR12 Proline-rich protein 12 0 114.03 6.8806e-05 3742000.0 36177.0 43319.0 46031.0 39513.0 35727.0 49157.0 33321.0 58664.0 41855.0 42177.0 False True 47680.53347165404 57321.01960078449 45420.598863878906 30403.888319764526 30766.92274290987 46083.205019115056 36286.50444866976 49598.82676461127 44067.36985132398 40700.39606767968 1.1715004785793057 1.4083651546158615 1.1159743700859843 0.7470170135250442 0.7559366914206023 1.132254461172428 0.89155162982517 1.2186325332592494 1.0827258235533002 1.0 15.312755213404536 -5.519949960594055 24.963925590415 0.9748354186055844 1.2829920950791953 0.40612515410237426 0.1521164804518258 109.70245510018785 935063.6608421121 0.043665574205127226 0.07749801692991087 3.0202996992562914e-06 5.519949960594055 0.3081566764736109 TEDEEFLIQHLLQAPSPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEDEEFLIQHLLQAPSPPR 19 0 Q9ULL5;Q9ULL5-2 Q9ULL5 PRR12 Proline-rich protein 12 0 132.87 3.6111e-05 3983100.0 29242.0 26129.0 27843.0 25942.0 33093.0 22980.0 27810.0 19639.0 25792.0 26065.0 False True 34192.09304417358 28722.914439454824 28506.88271516552 24488.553845098773 26608.664210088198 21774.888346022017 25175.635473035753 19123.49705924052 26169.159206329878 30790.378169573512 1.1104798017051178 0.9328535778699296 0.9258373690043047 0.7953313762575971 0.8641876388638315 0.7071978208939169 0.8176461924041535 0.6210867873697637 0.8499135366966607 1.0 14.910191966322172 -4.475439686434154 0.7316422667296908 0.782170811234593 1.4353490556089867 0.4640840561035712 0.09779145770586824 3.3203079926775088 0.9910679440664635 0.03710598667109407 1.9778145315644033 3.3462648658844193e-05 4.475439686434154 0.6531782443743938 TEDGGEFEEGAS(ph)ENNAK ddPTM_PC-9_AZD4547_30min_R2 2 TEDGGEFEEGASENNAK 17 0 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 TEDGGEFEEGAS(1)ENNAK;TEDGGEFEEGAS(1)ENNAK 269.87 1.0452999999999998e-69 14414000.0 40880.0 41509.0 39409.0 37126.0 43644.0 46800.0 46548.0 53664.0 46139.0 36668.0 True False 53878.98964317704 54925.97249726365 38886.41091061685 28567.17429098216 37584.783950277364 43873.58860171668 50690.68182457549 45371.461876041525 48577.81334536463 35384.26448087055 1.522682198814818 1.5522711381201024 1.0989746849659578 0.807341192761719 1.0621892104213855 1.2399180609062999 1.4325769538598123 1.2822496819333422 1.3728648612048098 1.0 15.11082031041138 -5.256209686880621 24.71581427475008 1.168307820403661 1.5374767230589794 0.42484860835326577 0.17462043832326002 395.8380197646957 1870734.674410654 0.05084206622340897 0.12628732789677194 5.5435799216135645e-06 5.256209686880621 0.36916890265531843 TEDGGEFEEGAS(ph)ENNAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEDGGEFEEGASENNAK 17 0 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 TEDGGEFEEGAS(1)ENNAK 149.31 5.4088e-05 6550600.0 45597.0 59966.0 49388.0 46782.0 40917.0 36718.0 47685.0 29492.0 32330.0 33711.0 True False 53315.67151819926 65919.02817851231 50565.59722503304 44160.95620929036 32899.607575142145 34792.443441655196 43167.93159049659 28717.866249356954 32802.76508764906 39822.53744387084 1.3388315999036162 1.6553196358073368 1.2697733612857882 1.108943805289516 0.8261554809638527 0.8736872553813159 1.0840075585675832 0.7211460668430353 0.8237236297130481 1.0 15.281297530317985 -5.777630368693717 1.909912040322989 0.8842651597720725 1.4959151159264958 0.791014063403262 0.12450442949683972 0.13787343146268016 1.0264645686413265 0.03780848285590582 0.07487409495786956 1.6686668232526139e-06 5.777630368693717 0.6116499561544233 TEDGGEFEEGAS(ph)ENNAK ddPTM_PC-9_Lapatinib_30min_R1 2 TEDGGEFEEGASENNAK 17 0 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 TEDGGEFEEGAS(1)ENNAK;TEDGGEFEEGAS(1)ENNAK 268.93 1.4276999999999998e-69 14067000.0 41200.0 68725.0 52827.0 57123.0 65014.0 56845.0 69102.0 69802.0 58033.0 56942.0 True False 40612.48044484536 68565.87148495139 48483.76797811706 61324.01597674189 61190.00434244189 54413.87186216715 72679.76344131722 73045.25574472926 51496.71242541807 66784.34882955441 0.6081137445615539 1.0266757509299633 0.725975005039823 0.9182393337883961 0.916232701446408 0.814769819812739 1.0882753925894968 1.093748116510858 0.7710895341189428 1.0 16.027222420697598 -3.218723029592012 0.3780941196120961 0.9767454537836663 8.182236082182452e-14 0.266403305131783 0.1323725341514327 28.47943915008087 1.2648409976518298 0.10444291729202111 16.101169825209645 0.0006043339192120205 3.218723029592012 -0.9767454537835845 TEEAAADGGGGMQNEPLT(ph)PGYHGFPAR ddPTM_PC-9_AZD4547_30min_R2 4 TEEAAADGGGGMQNEPLTPGYHGFPAR 27 0 O43251-6;O43251-8 O43251-6 1 TEEAAADGGGGMQNEPLT(1)PGYHGFPAR;TEEAAADGGGGMQNEPLT(1)PGYHGFPAR;TEEAAADGGGGMQNEPLT(0.996)PGY(0.004)HGFPAR;TEEAAADGGGGMQNEPLT(0.974)PGY(0.026)HGFPAR 176.38 2.0597e-17 52109200.0 39776.1 44083.9 60269.3 82845.0 61941.8 65487.3 51818.8 63028.3 46331.6 60753.5 True False 52424.072405723484 58333.15856734971 59470.08970273895 63746.36519249087 53342.25026329599 61392.36877857265 56430.572813682906 53288.72448124829 48780.59378816393 58626.53845692617 0.8942037818630596 0.9949957835257148 1.014388556241173 1.087329507597081 0.90986525330141 1.0471771043360947 0.9625431468232313 0.9089522575241303 0.8320565237533816 1.0 15.83926625636818 -7.660722303325571 3.7499487882485476 0.9022983971976026 0.9938982945289085 0.20927385123819464 0.06603954042252633 0.3070832302926424 8.17905467787038 0.033672116742512276 0.017873092611138786 2.1841260397984512e-08 7.660722303325571 0.09159989733130591 TEEAAADGGGGMQNEPLT(ph)PGYHGFPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TEEAAADGGGGMQNEPLTPGYHGFPAR 27 0 O43251-6;O43251-8 O43251-6 1 TEEAAADGGGGMQNEPLT(0.973)PGY(0.027)HGFPAR;TEEAAADGGGGMQNEPLT(1)PGYHGFPAR 95.152 3.0891999999999996e-09 28383000.0 24755.7 23049.0 30737.0 33126.0 43379.0 45816.0 49643.0 53479.0 52350.0 39149.0 True False 28946.35106263756 25337.15239446569 31469.88665072163 31270.05761594101 34879.196348757054 43413.32830554157 44940.45565580421 52075.23291568431 53115.5197135301 46246.40379668654 0.625915718547428 0.547872922311011 0.6804828930931139 0.6761619293343073 0.7542034295703675 0.9387395503529301 0.9717610877026528 1.1260385379287674 1.1485329745214852 1.0 15.497053562985881 -6.79369246465055 0.9817328679292372 1.1040200061759793 0.6024179237881092 0.934238896231175 0.0525578648615027 0.11854049328341411 0.24481715535119639 0.030604223098304028 0.027034304608128508 1.6080795733844437e-07 6.79369246465055 -0.5016020823878701 TEEAAADGGGGMQNEPLT(ph)PGYHGFPAR ddPTM_PC-9_Lapatinib_30min_R1 5 TEEAAADGGGGMQNEPLTPGYHGFPAR 27 0 O43251-6;O43251-8 O43251-6 1 TEEAAADGGGGMQNEPLT(1)PGYHGFPAR;TEEAAADGGGGMQNEPLT(1)PGYHGFPAR;TEEAAADGGGGMQNEPLT(0.996)PGY(0.004)HGFPAR;TEEAAADGGGGMQNEPLT(1)PGYHGFPAR;TEEAAADGGGGMQNEPLT(0.982)PGY(0.018)HGFPAR 168.41 3.3911e-16 23392000.0 26602.899999999998 31804.499999999996 30617.199999999997 26442.9 45315.4 56132.5 56242.200000000004 52785.7 63001.100000000006 53180.700000000004 True False 26223.53776762562 31730.858634312644 28099.972001809783 28387.599076928524 42650.03726550426 53731.84382624849 59154.14592080193 55238.31632567191 55905.25268700582 62372.913136171555 0.4204315054256775 0.508728180853736 0.45051562591701255 0.45512703591306003 0.6837910099275205 0.8614611876303097 0.9483947910474781 0.8856138594180537 0.896306583676064 1.0 15.928632021326615 -6.561957783528326 1.9698156762669312 0.9230384254935827 0.4571028208224467 0.970084967531334 0.0381591319305378 0.050925898809202265 0.4005624450802354 0.014173526605166123 0.0149438356343226 2.7418406851320013e-07 6.561957783528326 -0.46593560467113604 TEEARPS(ph)PAPGPGTPTGTPTR ddPTM_PC-9_AZD4547_30min_R2 1 TEEARPSPAPGPGTPTGTPTR 21 1 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 TEEARPS(0.99)PAPGPGT(0.01)PTGTPTR 118.24 1.2610999999999998e-05 4975900.0 3610.1 4612.1 7129.6 9418.8 9557.6 8553.2 7236.3 9439.0 8129.8 8683.7 True False 4758.036705255222 6102.871130468806 7035.056845602117 7247.441179009392 8230.692216184832 8018.367051884677 7880.316681429394 7980.419436641995 8559.524630684353 8379.68630611257 0.5678060647430762 0.7282935073616135 0.8395370170922017 0.8648821583837499 0.9822196100802659 0.9568815298056769 0.9404071218848717 0.9523530052456345 1.021461223964983 1.0 13.032680522251805 -4.267720143116253 0.5844380412049459 0.9834487065603567 1.2010773711288259e-17 0.9628548387256327 0.025980133194652894 1.1249424191820736 0.1883364463269155 0.013245581782427723 0.8519624440547108 5.398583921173015e-05 4.267720143116253 -0.9834487065603567 TEEARPS(ph)PAPGPGTPTGTPTR ddPTM_PC-9_Lapatinib_30min_R1 1 TEEARPSPAPGPGTPTGTPTR 21 1 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 TEEARPS(0.645)PAPGPGT(0.349)PT(0.006)GTPTR 112.16 9.0879e-05 8699800.0 6527.4 8398.7 7236.5 6860.3 5681.1 5863.7 6605.4 7127.4 6681.8 7501.2 True False 6434.318079021446 8379.253326164588 6641.54290369781 7364.82934728992 5346.948867472342 5612.9232199523185 6947.395291529578 7458.565023852934 5929.225321526696 8797.77242527928 0.7313576400923092 0.9524289696432553 0.754911877990181 0.8371243300324547 0.6077616706825201 0.6379936816533578 0.7896766312762445 0.8477788084653902 0.6739462030740669 1.0 13.102922567750614 -10.35477119417134 10.79610707576018 0.9999926556188893 0.7625475267734908 0.3470735042066746 0.09898012425703298 0.0 0.0 0.1001206604222787 0.024282826954567814 4.418031477803248e-11 10.35477119417134 -0.23744512884539848 TEEARPSPAPGPGT(ph)PTGTPTR ddPTM_PC-9_AZD4547_30min_R2 5 TEEARPSPAPGPGTPTGTPTR 21 1 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 T(0.089)EEARPS(0.06)PAPGPGT(0.769)PT(0.057)GT(0.021)PT(0.005)R;TEEARPSPAPGPGT(0.877)PT(0.084)GT(0.029)PT(0.01)R;T(0.002)EEARPS(0.373)PAPGPGT(0.619)PT(0.006)GTPTR;TEEARPS(0.007)PAPGPGT(0.854)PT(0.09)GT(0.039)PT(0.01)R;TEEARPS(0.001)PAPGPGT(0.747)PT(0.226)GT(0.022)PT(0.005)R 100.94 0.00013296 123681800.0 34079.2 32558.800000000003 62445.100000000006 82669.0 70993.29999999999 81723.2 57746.700000000004 95804.0 72935.4 64988.0 True False 44915.67670860472 43082.79537796401 61617.03717309651 63610.939273318 61137.10572855886 76613.03538495317 62886.04442981896 80999.69315690754 76790.61634342985 62712.789900807664 0.7162123831462051 0.6869857878449952 0.9825274440916392 1.0143216299885707 0.9748745961590761 1.2216492920524094 1.0027626665834088 1.2915976674777845 1.2244809466280957 1.0 15.936472081663851 -5.29821124678115 0.6728101112057329 1.1623767767123672 0.5272267885617287 0.7049457454011923 0.10347428007572979 0.9488176288780322 0.5101646372580327 0.050062344993859274 0.4175854388128788 5.032557587532917e-06 5.29821124678115 -0.6351499881506385 TEEARPSPAPGPGT(ph)PTGTPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TEEARPSPAPGPGTPTGTPTR 21 1 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 TEEARPSPAPGPGT(0.856)PT(0.083)GT(0.03)PT(0.03)R;T(0.003)EEARPS(0.049)PAPGPGT(0.747)PT(0.077)GT(0.101)PT(0.023)R;TEEARPS(0.004)PAPGPGT(0.97)PT(0.026)GTPTR;TEEARPSPAPGPGT(0.712)PT(0.252)GT(0.018)PT(0.018)R 101.38 0.00055554 94770500.0 34807.6 27933.9 33341.600000000006 44312.9 51879.6 47618.6 50772.1 28670.0 46786.5 38642.100000000006 True False 40699.83919856288 30706.992983286284 34136.590192722135 41830.191877360165 41714.164800824714 45121.39678824563 45962.599129828064 27917.442878375972 47470.66405113805 45647.60683930473 0.8916094844104381 0.6726966671305564 0.7478286936902228 0.9163720679731759 0.9138302682038275 0.9884723408849988 1.0069005214584898 0.6115861227217227 1.0399376295509006 1.0 15.478251605770556 -5.7640209391834265 24.94660470761153 0.9146702714156293 0.7609100983150132 0.24198259723620164 0.12402616968007776 92.8531329054458 897290.4558532314 0.03410129262571635 0.05332860874575816 1.7217855583825884e-06 5.7640209391834265 -0.15376017310061607 TEEARPSPAPGPGT(ph)PTGTPTR ddPTM_PC-9_Lapatinib_30min_R1 6 TEEARPSPAPGPGTPTGTPTR 21 1 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 TEEARPSPAPGPGT(0.778)PT(0.199)GT(0.018)PT(0.004)R;TEEARPS(0.005)PAPGPGT(0.991)PT(0.004)GTPTR;TEEARPSPAPGPGT(0.607)PT(0.232)GT(0.129)PT(0.031)R;T(0.006)EEARPS(0.005)PAPGPGT(0.67)PT(0.282)GT(0.029)PT(0.008)R;TEEARPS(0.315)PAPGPGT(0.54)PT(0.145)GT(0.001)PTR;TEEARPS(0.001)PAPGPGT(0.985)PT(0.013)GT(0.001)PTR 114.74 2.6119e-06 125724800.0 73764.5 75010.4 84782.0 73528.5 73419.8 77146.9 78573.5 69933.1 76162.2 65628.0 True False 72712.60470324739 74836.71802742529 77811.55122798402 78936.03117388554 69101.39171288052 73847.50692520755 82641.65136691187 73182.44712933319 67584.01101247872 76971.7123561867 0.9446665856512287 0.9722626109851665 1.0109110067333693 1.0255200093328956 0.8977504799830064 0.9594109922289127 1.0736626331565486 0.9507706778131856 0.8780369949382653 1.0 16.232040722219438 -7.991314655410982 24.998508874950883 0.9308135826120888 0.9836729031763092 0.1091608722970534 0.0527127739200798 345.3555964859568 994016.0409280923 0.029073307204008133 0.013935244091119103 1.0202000596526253e-08 7.991314655410982 0.05285932056422038 TEEDSEEVR ddPTM_PC-9_Lapatinib_30min_R1 2 TEEDSEEVR 9 0 Q16543;K7EKQ2 Q16543 CDC37 Hsp90 co-chaperone Cdc37;Hsp90 co-chaperone Cdc37, N-terminally processed 0 ; 129.42 0.005982899999999999 4347500.0 7203.7 14334.1 12466.099999999999 12150.199999999999 14056.5 14771.7 13911.3 11966.5 13085.0 12561.6 False True 7100.9739170032135 14300.910272134475 11441.185378537588 13043.766239879018 13229.724306142289 14139.948825514546 14631.559045486329 12522.507275856015 11611.229508841445 14732.855822720117 0.48198217660234766 0.9706814784734727 0.7765762128000795 0.8853521949060081 0.8979741921956644 0.9597561393160974 0.9931244302901835 0.8499714805153094 0.7881180436813419 1.0 13.846749489619821 -4.755278643628125 24.997560719198678 0.8977317943591469 0.48198149234088167 0.7330551145613092 0.07606278527568815 108.189817265334 438944.5253162801 0.01913042157111409 0.1722628218704312 1.7567960907485508e-05 4.755278643628125 -0.4157503020182652 TEEGEIDYS(ph)AEEGENRR ddPTM_PC-9_AZD4547_30min_R2 1 TEEGEIDYSAEEGENRR 17 1 B7WPG3;V9GYK2;Q8WVV9-2;Q8WVV9-5;Q8WVV9;C9IYN3;Q8WVV9-3;Q8WVV9-4 B7WPG3 HNRNPLL Heterogeneous nuclear ribonucleoprotein L-like 1 TEEGEIDY(0.035)S(0.965)AEEGENRR 96.455 0.00071074 17190000.0 26726.0 31957.0 47924.0 48869.0 44200.0 42141.0 36109.0 52577.0 41540.0 47047.0 True False 35224.31206466609 42286.47529680439 47288.496447014644 37603.00706852356 38063.592947535966 39505.916608225256 39322.63104759807 44452.43274926643 43735.719594409224 45399.898849992285 0.7758676331207746 0.9314222359068445 1.0415991586955415 0.8282619129344151 0.8384069989517704 0.8701763133604861 0.866139177479792 0.9791306561308337 0.963343987591652 1.0 15.470401462775396 -7.767544641923491 24.838409253630903 0.9784280328125017 0.8832879564489677 0.3246169753191449 0.06717142839061577 189.17022696093994 769595.014864345 0.03756073571172789 0.01877647810895602 1.7078721557364578e-08 7.767544641923491 -0.09514007636353394 TEEGEIDYS(ph)AEEGENRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEEGEIDYSAEEGENRR 17 1 B7WPG3;V9GYK2;Q8WVV9-2;Q8WVV9-5;Q8WVV9;C9IYN3;Q8WVV9-3;Q8WVV9-4 B7WPG3 HNRNPLL Heterogeneous nuclear ribonucleoprotein L-like 1 TEEGEIDYS(1)AEEGENRR 97.49 0.0006642 6757200.0 19187.0 17215.0 20193.0 25753.0 28369.0 25163.0 19407.0 24304.0 17223.0 21442.0 True False 22434.980139476058 18923.991430028505 20674.47770237897 24310.142902352512 22810.298098570485 23843.40798307015 17568.62846548741 23666.0457522166 17474.853792285183 25329.264865221405 0.8857335678257535 0.7471196472035111 0.8162288882993309 0.9597650398346852 0.9005511300839366 0.9413383337393488 0.6936098840203684 0.9343360685019918 0.6899076576154092 1.0 14.62851758566856 -5.554750877406788 24.995523630399525 0.869398229723604 0.8077383235440381 0.05830704572625023 0.10414512828488169 543.1094299493672 425927.82634328055 0.027272862807770963 0.047238359856605044 2.7877198185558714e-06 5.554750877406788 -0.06165990617956596 TEEGEIDYS(ph)AEEGENRR ddPTM_PC-9_Lapatinib_30min_R1 2 TEEGEIDYSAEEGENRR 17 1 B7WPG3;V9GYK2;Q8WVV9-2;Q8WVV9-5;Q8WVV9;C9IYN3;Q8WVV9-3;Q8WVV9-4 B7WPG3 HNRNPLL Heterogeneous nuclear ribonucleoprotein L-like 1 T(0.001)EEGEIDY(0.009)S(0.99)AEEGENRR;TEEGEIDY(0.055)S(0.945)AEEGENRR 66.264 0.009337200000000002 29689000.0 33997.0 44923.0 47633.0 35168.0 46553.0 41342.0 43088.0 50158.0 55325.0 45251.0 True False 33512.19654571377 44818.98355356091 43716.798608697245 37754.37203700889 43814.84406671948 39573.89903290903 45318.88580879683 52488.523790781415 49093.71590192227 53072.57505683259 0.6314409374300634 0.8444848117048522 0.82371730713807 0.7113725308519466 0.8255646917414597 0.7456562827511469 0.8539040316070448 0.9889952340653201 0.9250298454399551 1.0 15.69567892889433 -7.56528771802375 3.248957307450637 0.9678640953131635 0.7710379453295976 0.6894024661015626 0.062162461882413304 0.14412692778372632 3.133496902189496 0.031089567348497996 0.017136366395574466 2.7208981288066488e-08 7.56528771802375 -0.19682614998356596 TEELIES(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 TEELIESPK 9 0 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 TEELIES(1)PK 78.342 0.021741999999999997 7361700.0 48599.0 49411.0 30170.0 28130.0 36518.0 38188.0 51275.0 43173.0 41645.0 36483.0 True False 64052.47107800297 65382.13946523148 29769.92608727219 21645.063104167624 31448.10604656373 35800.09832312726 55838.37566716312 36501.60486684445 43846.269680047466 35205.74127456093 1.8193757256372896 1.8571442355192076 0.8455986157230392 0.6148162862234058 0.8932664079221532 1.0168823898332686 1.5860587973902704 1.0368083030031208 1.2454295263406379 1.0 15.10352309912002 -5.254135160483272 24.862696340553985 1.0308718956194083 1.8382601098026647 0.6422130142951135 0.2413562780662233 351.17715844322765 1195357.3951189094 0.069035252109869 0.17481249953365377 5.570123693920176e-06 5.254135160483272 0.8073882141832565 TEELIES(ph)PKLESSEGEIIQTVDR ddPTM_PC-9_AZD4547_30min_R2 3 TEELIESPKLESSEGEIIQTVDR 23 1 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 TEELIES(1)PKLESSEGEIIQTVDR;T(0.007)EELIES(0.993)PKLESSEGEIIQTVDR;T(0.006)EELIES(0.974)PKLES(0.004)S(0.011)EGEIIQT(0.005)VDR 72.015 0.00035716 72944900.0 24110.8 23718.9 17792.5 21412.4 17746.4 22667.0 18865.3 19354.8 15943.6 17021.2 True False 31777.532864205325 31385.570576630296 17556.55982458703 16476.101998282236 15282.618685161804 21249.628906733138 20544.27515307133 16363.960389057995 16786.346146495496 16425.292968850055 1.9346706889472358 1.9108073527913225 1.0688734659334467 1.0030933408328568 0.9304320302928362 1.2937138440715945 1.2507706980954778 0.9962659673767539 1.0219815365442897 1.0 14.003631482878648 -5.259111092930362 9.629127860485424 1.0773227391988294 1.9236850594228658 0.9063850889013052 0.10952196686051069 0.030494563103277618 58.76379037152852 0.030931879264391234 0.07303297228263368 5.50666817306222e-06 5.259111092930362 0.8463623202240365 TEELIES(ph)PKLESSEGEIIQTVDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 TEELIESPKLESSEGEIIQTVDR 23 1 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 T(0.011)EELIES(0.987)PKLES(0.001)S(0.001)EGEIIQTVDR;T(0.001)EELIES(0.566)PKLES(0.214)S(0.214)EGEIIQT(0.004)VDR;T(0.01)EELIES(0.989)PKLES(0.001)SEGEIIQTVDR;T(0.006)EELIES(0.988)PKLES(0.003)S(0.001)EGEIIQT(0.002)VDR;T(0.006)EELIES(0.98)PKLES(0.006)S(0.006)EGEIIQT(0.002)VDR;T(0.001)EELIES(0.833)PKLES(0.099)S(0.065)EGEIIQT(0.002)VDR 65.598 0.00082726 116780900.0 34694.9 33075.5 26202.62 35975.9 36396.3 30664.6 39174.3 37793.1 29748.600000000002 32638.600000000002 True False 40568.06131448934 36359.01705163564 26827.389834789723 33960.28695844148 29264.706288025685 29056.494394056877 35463.426706628736 36801.071170099436 30183.616996178083 38555.71981298456 1.0521930730710176 0.9430252431544768 0.6958082993889524 0.8808106066536086 0.7590237305897761 0.7536234451073952 0.9197967740881233 0.9544905749031249 0.7828570479966251 1.0 15.234657282068529 -9.924213540325459 11.657132859957168 1.0000022816902066 0.8568077958454346 0.1358235915864976 0.10549540797361211 0.0 0.0 0.10544616551007553 0.02557445165967079 1.1906564245380063e-10 9.924213540325459 -0.1431944858447719 TEELIES(ph)PKLESSEGEIIQTVDR ddPTM_PC-9_Lapatinib_30min_R1 4 TEELIESPKLESSEGEIIQTVDR 23 1 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 T(0.001)EELIES(0.998)PKLES(0.001)SEGEIIQTVDR;T(0.001)EELIES(0.999)PKLESSEGEIIQTVDR;T(0.001)EELIES(0.998)PKLESSEGEIIQTVDR;T(0.033)EELIES(0.957)PKLES(0.006)S(0.004)EGEIIQTVDR 77.28699999999999 0.00014718 59264800.0 36262.5 32650.7 29370.399999999998 33415.4 33593.9 27489.0 30795.0 28399.12 28041.100000000002 26560.8 True False 35745.39010027196 32575.09931020303 26955.679085022606 35872.87998650668 31617.972850148577 26313.359549988778 32389.414418907756 29718.646791284667 24882.816032126382 31151.798889958645 1.1474582969201819 1.0456891887775754 0.8653008829519441 1.1515508338129974 1.014964591991514 0.8446818638929557 1.0397285413057813 0.9539945637253091 0.7987601653446413 1.0 14.927027854987761 -6.542548385559153 23.17734463007248 0.9313812851208807 1.0442189454066542 0.26846816073387314 0.0981103970218591 157.06459446724202 185071.35397267764 0.032332931719165 0.03233939366658394 2.867157922368458e-07 6.542548385559153 0.11283766028577347 TEENVSDGS(ph)PNAGSVEQTPK ddPTM_PC-9_AZD4547_30min_R2 1 TEENVSDGSPNAGSVEQTPK 20 0 P46527;H7C2T1 P46527 CDKN1B Cyclin-dependent kinase inhibitor 1B 1 TEENVSDGS(1)PNAGSVEQTPK 234.22 3.9250999999999985e-103 0.0 13075.0 13831.0 17126.0 13326.0 17917.0 16236.0 14607.0 17715.0 17898.0 13619.0 True False 17232.578023105183 18301.60027005357 16898.898050070384 10253.896584647635 15429.533819932172 15220.760353364787 15906.994702491495 14977.553800202668 18844.051740508818 13142.202955300974 1.3112396819404113 1.392582380008941 1.2858497245512501 0.7802266195038232 1.1740447071477154 1.1581589787597533 1.2103750609082877 1.1396532111963311 1.4338579159522091 1.0 13.681919506526407 -5.538419353459176 24.963392633699687 1.1322022279025457 1.3487374609905964 0.2655565357323936 0.15629457041724845 297.686920211447 478182.5464669211 0.04280284077895175 0.07416847796066789 2.8945472716306364e-06 5.538419353459176 0.21653523308805078 TEENVSDGS(ph)PNAGSVEQTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEENVSDGSPNAGSVEQTPK 20 0 P46527;H7C2T1 P46527 CDKN1B Cyclin-dependent kinase inhibitor 1B 1 TEENVS(0.204)DGS(0.769)PNAGS(0.027)VEQTPK 183.18 1.1685e-37 0.0 9581.0 10474.0 8483.7 11563.0 9965.8 9528.3 8702.4 8564.6 9188.7 6712.2 True False 11202.874066624272 11513.789499745488 8685.983582611421 10915.162597751805 8013.073030093886 9028.619174386493 7878.045672080055 8339.78832494381 9323.067354187473 7929.068726254033 1.4128864881105525 1.452098587772615 1.0954607511284595 1.3766008310169493 1.0105944729122733 1.138673340601996 0.9935650634474846 1.051799222944031 1.1758086196576598 1.0 12.952935715167389 -5.266130737945425 0.6440439201167311 1.0534911475589293 1.5741435233146703 0.6093358191583177 0.10593014331738405 1.3157904213896254 0.6244763578184213 0.05206167277702131 0.4623440090947929 5.418377535874091e-06 5.266130737945425 0.5206523757557411 TEENVSDGS(ph)PNAGSVEQTPK ddPTM_PC-9_Lapatinib_30min_R1 2 TEENVSDGSPNAGSVEQTPK 20 0 P46527;H7C2T1 P46527 CDKN1B Cyclin-dependent kinase inhibitor 1B 1 TEENVSDGS(1)PNAGSVEQTPK;TEENVS(0.023)DGS(0.973)PNAGS(0.005)VEQTPK 261.94 1.2372999999999995e-157 3298700.0 27974.0 27903.0 34219.0 30235.0 32483.0 33878.0 33183.0 32862.0 34890.0 25913.0 True False 27575.085630196692 27838.392317855225 31405.645909159866 32458.582761003287 30572.41380403514 32429.116913475216 34901.05337433402 34388.88848862913 30960.320792012095 30392.02752309789 0.9073131303674844 0.9159768066377965 1.0333514565716824 1.067996623006965 1.005935315792938 1.0670270974461686 1.148362127133811 1.131510178532631 1.0186987613275325 1.0 14.891405303173935 -5.323494952319508 2.4217692596996336 1.0699450654943898 0.9019522764940984 0.618444670533036 0.04655299333379265 0.20039398868683267 2.235148763781487 0.013736123148013063 0.04193017730106932 4.74793809302114e-06 5.323494952319508 -0.16799278900029146 TEEPAS(ph)DKGSEAEAHMPPPFTPYVPR ddPTM_PC-9_AZD4547_30min_R2 1 TEEPASDKGSEAEAHMPPPFTPYVPR 26 1 O94886 O94886 TMEM63A CSC1-like protein 1 1 T(0.144)EEPAS(0.428)DKGS(0.428)EAEAHMPPPFTPYVPR 40.681999999999995 0.041518 6833800.0 10203.0 11568.0 10323.0 13131.0 9280.0 8718.1 8671.5 12873.0 10258.0 8846.0 True False 13447.34176441623 15307.12977543052 10186.110275071627 10103.850821927665 7991.632184460036 8172.955828816795 9443.246701078591 10883.773642111699 10800.216937877936 8536.304232512852 1.5753119146337764 1.793179970921037 1.1932693584508196 1.1836329337284375 0.9361934587595551 0.9574349280673309 1.1062453309842684 1.2749983301506367 1.2652099367244145 1.0 13.05939587916042 -5.345790521074178 4.637845357581016 1.1082810361038946 1.6833470592436108 0.7779850480181392 0.12214353922797151 0.09823772467340787 3.704659719517985 0.03545129270842785 0.07843347582399837 4.510342052973462e-06 5.345790521074178 0.5750660231397162 TEEPASDKGS(ph)EAEAHMPPPFTPYVPR ddPTM_PC-9_AZD4547_30min_R2 1 TEEPASDKGSEAEAHMPPPFTPYVPR 26 1 O94886 O94886 TMEM63A CSC1-like protein 1 1 T(0.049)EEPAS(0.152)DKGS(0.799)EAEAHMPPPFTPYVPR 48.198 0.014228999999999999 7777300.0 14419.0 20038.0 20045.0 23407.0 16681.0 12824.0 18645.0 19871.0 16142.0 16508.0 True False 19003.942066168554 26514.891635552973 19779.19020282966 18010.877784545042 14365.131085019158 12022.113252743891 20304.368879848975 16800.393540153942 16995.233165453872 15930.05994464414 1.1929611145347816 1.6644564884055926 1.2416268533552908 1.1306220972884975 0.9017625253725974 0.7546809801419396 1.2745946311818823 1.054634671717128 1.066865612842082 1.0 13.9594640752688 -5.682693293761737 2.644559493405256 1.015562543225011 1.4314878953037338 0.4897058200174499 0.16637845860499642 0.21808826987502603 3.0813880572273824 0.0483861182388498 0.09313409234321003 2.0763793746405277e-06 5.682693293761737 0.4159253520787227 TEEPDRDER ddPTM_PC-9_AZD4547_30min_R2 2 TEEPDRDER 9 1 O95232;J3KPP4;H0YA81 O95232 LUC7L3 Luc7-like protein 3 0 ; 104.06 0.0035369 23873000.0 102738.0 101098.0 115617.0 116321.0 113179.0 103930.0 90513.0 116892.0 96288.0 99030.0 False True 135406.5469168472 133775.95142085716 114083.8430371942 89504.99059153514 97466.04946174573 97431.24067043602 98568.48165308479 98829.02731093942 101377.58710415193 95562.98984238603 1.416935019929535 1.3998719759762284 1.1938078038930655 0.9366072654189402 1.0199141908650875 1.0195499411553712 1.0314503744143604 1.0341768029018361 1.060845702623537 1.0 16.54416437109282 -5.448900994651264 2.9057761368190236 1.0176484886468402 1.411720909474908 0.9547519401414121 0.034169774297189294 0.04924974409731157 0.8034425122287463 0.009762736631112682 0.02298228849371423 3.5571240045651e-06 5.448900994651264 0.3940724208280677 TEEPDRDER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TEEPDRDER 9 1 O95232;J3KPP4;H0YA81 O95232 LUC7L3 Luc7-like protein 3 0 ; 86.13600000000001 0.015421 16350500.0 59352.0 75716.0 64244.0 64975.0 75439.0 52835.0 60158.0 52576.0 51741.0 43384.0 False True 69399.12134456559 83232.5840903884 65775.82060672683 61334.66140179219 60657.26949339264 50064.23958929825 54459.398733796705 51195.93570887668 52497.614240644936 51249.17577244494 1.354150975085131 1.6240765404687723 1.2834512870759651 1.1967931284227578 1.183575512759878 0.9768789221429042 1.0626395042059935 0.9989611527841021 1.0243601667613793 1.0 15.645241181854006 -5.8723772173065685 1.0248886417370442 1.0151530770504544 1.5072205645712238 0.8234423112931584 0.082130875182535 0.2194139125741704 0.4543003227844161 0.03148431082038379 0.07917822958351436 1.341599175492406e-06 5.8723772173065685 0.49206748752076934 TEEPDRDER ddPTM_PC-9_Lapatinib_30min_R1 2 TEEPDRDER 9 1 O95232;J3KPP4;H0YA81 O95232 LUC7L3 Luc7-like protein 3 0 ; 131.22 0.0016081 17297000.0 46386.0 58289.0 65905.0 58592.0 69873.0 62641.0 60331.0 57525.0 61341.0 51164.0 False True 45724.527133849435 58154.03540176547 60486.54530065701 62901.05113718221 65763.2075156034 59961.99045330303 63454.64397814988 60197.82150533719 54432.130630633794 60007.629228255326 0.761978563757681 0.9691106972508577 1.0079809197357221 1.0482175674349834 1.0959141089453004 0.9992394504575627 1.0574429417430056 1.0031694682747492 0.9070868376350346 1.0 15.872858312771612 -4.699852450529931 2.3052824288677987 1.0199863996834326 0.6600821292162449 0.7211026545420962 0.04690766975820962 0.4356588684926096 2.2752318434076124 0.012787600833835303 0.34716426251128274 1.9959403109500264e-05 4.699852450529931 -0.35990427046718776 TEEPLGS(ph)PHPSGTVESPGEGPQDTR ddPTM_PC-9_AZD4547_30min_R2 2 TEEPLGSPHPSGTVESPGEGPQDTR 25 0 M0R202;A0A0B4J2G2;Q9NWS9-2;Q9NWS9;A0A0A0MR84 M0R202 ZNF446 Zinc finger protein 446 1 T(0.003)EEPLGS(0.996)PHPS(0.001)GTVESPGEGPQDTR;T(0.003)EEPLGS(0.997)PHPSGTVESPGEGPQDTR 92.565 2.3121000000000003e-06 15978500.0 3046.8 3889.2 29666.0 60829.0 43631.0 37673.0 14701.7 43546.0 20083.9 35812.0 True False 4015.619022623091 5146.307842548788 29272.609456579936 46805.813848681595 37573.58877588101 35317.301354539995 16010.122819033291 36816.96628753174 21145.493951905515 34558.23278032444 0.11619862184936042 0.1489169852886347 0.8470516893226714 1.3544041486788716 1.087254345866706 1.0219649129352393 0.46327955832708484 1.06536021449839 0.611880071713175 1.0 15.076741823201006 -5.2807080714715635 4.6512766574069 0.9457454028854334 0.11943671755022824 0.6487147483361952 0.2358883684553677 0.11225930328867177 6.603034533515971 0.06480279233790426 0.15532437879125183 5.239525140269333e-06 5.2807080714715635 -0.8263086853352052 TEEPLGS(ph)PHPSGTVESPGEGPQDTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TEEPLGSPHPSGTVESPGEGPQDTR 25 0 M0R202;A0A0B4J2G2;Q9NWS9-2;Q9NWS9;A0A0A0MR84 M0R202 ZNF446 Zinc finger protein 446 1 T(0.007)EEPLGS(0.993)PHPSGTVESPGEGPQDTR;T(0.002)EEPLGS(0.998)PHPSGTVESPGEGPQDTR 109.53 1.9195e-07 10894700.0 3733.5 6760.7 19080.6 26212.0 31336.0 29666.0 20207.4 15799.8 21825.6 17001.8 True False 4365.507810013748 7431.857616090256 19535.553867578463 24743.4266204506 25195.93574735819 28110.262735991706 18293.20878309324 15385.071991271881 22144.75811002145 20084.091753825254 0.21736147511785217 0.37003702767264895 0.9726879416320972 1.231991315501629 1.254522039442452 1.3996282769738777 0.9108307713048105 0.7660327477015042 1.1026019190438978 1.0 14.293765600610222 -5.2572513272232175 3.1117343321187714 1.0983188862893245 0.24360095700346318 0.7766630935281058 0.17050381966866354 0.12471464497992375 2.456696710126711 0.05178645332211558 0.15147777533203 5.530299768646658e-06 5.2572513272232175 -0.8547179292858613 down TEEPLGS(ph)PHPSGTVESPGEGPQDTR ddPTM_PC-9_Lapatinib_30min_R1 3 TEEPLGSPHPSGTVESPGEGPQDTR 25 0 M0R202;A0A0B4J2G2;Q9NWS9-2;Q9NWS9;A0A0A0MR84 M0R202 ZNF446 Zinc finger protein 446 1 T(0.001)EEPLGS(0.999)PHPSGTVESPGEGPQDTR;TEEPLGS(0.998)PHPS(0.002)GTVESPGEGPQDTR;TEEPLGS(1)PHPSGTVESPGEGPQDTR 120.44 2.3903000000000003e-09 5434900.0 26444.9 18957.1 62354.0 20593.4 35692.6 53145.0 26208.7 32062.1 59348.0 25154.0 True False 26067.790876599294 18913.205999670747 57227.49481340059 22107.90733356854 33593.23144235154 50872.11223704589 27565.65824584603 33551.822214450614 52663.603277854214 29501.83538440184 0.8835989536563482 0.6410857410475046 1.9397943913570141 0.7493739642129993 1.138682763449792 1.7243710967197285 0.9343709598630768 1.137279148137003 1.7850958285021965 1.0 14.848517090552967 TEES(ph)PASDEAGEK ddPTM_PC-9_AZD4547_30min_R2 1 TEESPASDEAGEK 13 0 A6NL93;A6NEL0;P05114 A6NL93 HMGN1 Non-histone chromosomal protein HMG-14 1 TEES(0.999)PAS(0.001)DEAGEK 140.31 4.5988e-05 0.0 7961.0 17103.0 11002.0 9223.9 9517.1 15264.0 12409.0 13196.0 15888.0 10953.0 True False 10492.432400913223 22631.21028260618 10856.106291420909 7097.472362834404 8195.814942103943 14309.539667021425 13513.376960581705 11156.861413913313 16727.807244005136 10569.538803833737 0.9927048469804051 2.141172921792717 1.0271125820062488 0.6715025598146288 0.7754184070104547 1.3538471197845579 1.2785209658987384 1.0555674775389958 1.5826430608247257 1.0 13.367624806417806 TEES(ph)PASDEAGEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEESPASDEAGEK 13 0 A6NL93;A6NEL0;P05114 A6NL93 HMGN1 Non-histone chromosomal protein HMG-14 1 TEES(0.995)PAS(0.005)DEAGEK 160.46 2.6004e-12 0.0 18678.0 42576.0 23113.0 17486.0 18441.0 15350.0 19991.0 10368.0 16861.0 13920.0 True False 21839.81649268431 46802.6639050185 23664.10157654061 16506.316110376883 14827.61842982616 14545.01897786937 18097.307757693558 10095.850985804045 17107.560227121907 16443.585809340628 1.3281662981488138 2.846256555454752 1.439108346009204 1.00381487965968 0.9017265821304905 0.8845405829674453 1.1005694236967187 0.6139689422284761 1.0403789310604086 1.0 14.005237317574888 -5.533024790016844 4.196588567081735 0.9307787829827984 2.109966989234897 0.6124822999578439 0.3644213104876304 0.11263299702817672 4.688280081931372 0.09202284066851184 0.17986896515578246 2.930725951346492e-06 5.533024790016844 1.1791882062520989 TEES(ph)PASDEAGEK ddPTM_PC-9_Lapatinib_30min_R1 2 TEESPASDEAGEK 13 0 A6NL93;A6NEL0;P05114 A6NL93 HMGN1 Non-histone chromosomal protein HMG-14 1 T(0.285)EES(0.641)PAS(0.074)DEAGEK;T(0.037)EES(0.823)PAS(0.14)DEAGEK 193.51 1.4300999999999999e-06 13583000.0 78088.0 122692.0 96909.0 86426.0 107603.0 108281.0 133601.0 136244.0 92986.0 104648.0 True False 76974.45080041476 122407.91421217426 88941.516099558 92782.0563486843 101274.00309563761 103650.07404533935 140518.20606528642 142574.39362317545 82512.93749401068 122736.26736530515 0.6271532649050867 0.9973247259332598 0.7246555399541164 0.755946537566872 0.825135106921669 0.8444942662044728 1.144879252739992 1.1616321457684977 0.6722783677983618 1.0 16.90520208869338 -7.077075542674754 6.55288041782484 1.0079878084710499 0.796523841654223 0.29387275227579757 0.15225647833360864 0.31045616584679014 21.858910128684293 0.05704869502000065 0.04429320249816299 8.373836120746934e-08 7.077075542674754 -0.2114639668168269 TEES(ph)PASDEAGEKEAK ddPTM_PC-9_AZD4547_30min_R2 1 TEESPASDEAGEKEAK 16 1 A6NL93;A6NEL0;P05114 A6NL93 HMGN1 Non-histone chromosomal protein HMG-14 1 T(0.247)EES(0.75)PAS(0.004)DEAGEKEAK 76.76100000000001 0.0052821000000000005 6518600.0 18672.0 28085.0 25522.0 24025.0 20209.0 25776.0 25017.0 24787.0 28487.0 24991.0 True False 24609.30759827306 37162.927017891285 25183.56160422143 18486.407432549855 17403.32918273199 24164.22264525317 27243.464535649335 20956.738698595724 29992.764662636855 24116.072696668398 1.020452538346876 1.5410024461829264 1.0442646247164658 0.7665596162804621 0.7216485620038887 1.001996591617151 1.1296808099028903 0.8689946726479585 1.24368362294663 1.0 14.557707362974776 -1.7941507113167814 8.19038260271213 1.0302467967495816 1.1232242030083086 0.0 0.2256291541752349 0.0 0.0 0.055255666918602675 0.0 0.016063836999581776 1.7941507113167814 0.09297740625872697 TEESKADS(ph)PPPSYPTQQAEQAPNTCECHVCK ddPTM_PC-9_AZD4547_30min_R2 1 TEESKADSPPPSYPTQQAEQAPNTCECHVCK 31 1 E7EUR8;A0A1B0GVL4;P78312-4;P78312-6;P78312-2;P78312-5;P78312;D6RFZ4;P78312-3 E7EUR8 FAM193A Protein FAM193A 1 T(0.07)EES(0.053)KADS(0.689)PPPS(0.086)Y(0.076)PT(0.025)QQAEQAPNTCECHVCK 73.212 5.264099999999999e-06 13690000.0 19439.0 18129.0 25183.0 31199.0 23437.0 32620.0 24629.0 19912.0 23296.0 26214.0 True False 25620.19764368197 23988.844718082637 24849.056965720116 24006.552569744963 20183.177102067864 30580.26624333328 26820.933287304917 16835.057932240205 24527.3790002734 25296.25583892062 1.0128059190586987 0.9483160223725121 0.9823215389641795 0.9490160410541337 0.7978721131929013 1.2088850792014336 1.0602728505788765 0.6655157996282564 0.9696051129644161 1.0 14.62663624342714 TEESPAS(ph)DEAGEK ddPTM_PC-9_AZD4547_30min_R2 1 TEESPASDEAGEK 13 0 A6NL93;A6NEL0;P05114 A6NL93 HMGN1 Non-histone chromosomal protein HMG-14 1 T(0.092)EES(0.133)PAS(0.775)DEAGEK 122.78 0.00017656 6191100.0 28591.0 37568.0 23646.0 20738.0 22351.0 33275.0 37810.0 36625.0 38695.0 21101.0 True False 37682.343270256264 49711.12131771905 23332.43858997806 15957.174498906092 19247.94945634334 31194.308989788922 41175.01675232445 30965.4478087735 40740.338702591805 20362.260412644533 1.850597257211008 2.4413360948300955 1.1458668201438535 0.7836641991375881 0.9452756750125232 1.5319669013965618 2.0221240627467685 1.5207274232454375 2.0007768232495895 1.0 14.313610103296039 -7.005966136809411 24.910369690254946 1.693264539936999 1.4174165204513303 0.02819694517392657 0.5145339869279976 942.0413543264482 3933309.2290992877 0.20300787451888835 0.17331498059001854 9.863563916793254e-08 7.005966136809411 -0.2758480194856687 TEESPAS(ph)DEAGEKEAK ddPTM_PC-9_Lapatinib_30min_R1 2 TEESPASDEAGEKEAK 16 1 A6NL93;A6NEL0;P05114 A6NL93 HMGN1 Non-histone chromosomal protein HMG-14 1 TEES(0.007)PAS(0.993)DEAGEKEAK;T(0.104)EES(0.23)PAS(0.666)DEAGEKEAK 93.115 0.0013494000000000002 25613000.0 61589.0 73615.0 56804.0 61564.0 68129.0 65229.0 80159.0 80577.0 60788.0 61935.0 True False 60710.729565960675 73444.54899039194 52133.79438978099 66091.62193148369 64121.78616676754 62439.30772622569 84309.2407990008 84320.90158080046 53941.41531398194 72640.38222680004 0.8357710643152698 1.0110705194402902 0.7176971374821136 0.9098468359531809 0.8827291955398104 0.8595674446105717 1.160638727584994 1.1607992551241146 0.7425816558283572 1.0 16.14848417352269 -7.226756140800871 24.691977174363668 1.0294048751023197 0.8714268005754068 0.23678443195647914 0.1279718801236505 723.9117522658524 515373.6562482979 0.04802784378202007 0.0372001944674339 5.932583495264823e-08 7.226756140800871 -0.15797807452691293 TEFLDLDNSPLSPPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 9 TEFLDLDNSPLSPPSPR 17 0 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 TEFLDLDNSPLSPPS(1)PR;TEFLDLDNS(0.005)PLS(0.01)PPS(0.984)PR;TEFLDLDNSPLSPPS(1)PR;TEFLDLDNSPLSPPS(1)PR;TEFLDLDNSPLS(0.001)PPS(0.999)PR;TEFLDLDNSPLS(0.01)PPS(0.99)PR;TEFLDLDNSPLSPPS(1)PR;TEFLDLDNS(0.002)PLS(0.001)PPS(0.996)PR;TEFLDLDNSPLSPPS(1)PR 203.64 2.7332999999999994e-54 26175600.0 93116.8 91031.4 116379.8 167863.2 142884.2 126064.5 112130.3 152955.7 114618.8 116380.20000000001 True False 122726.00545023932 120455.51983394937 114836.52781078948 129164.93270058687 123047.19519082177 118181.66688634864 122109.67947482574 129319.91113732189 120677.31576908198 112305.76462137603 1.0927845588692062 1.0725675591101593 1.0225345795734135 1.150118456840121 1.095644516607487 1.05232057574945 1.087296630644939 1.151498425510986 1.074542488321321 1.0 16.777072457181774 -5.73893937038767 24.99976631009091 1.0925426858960596 1.063622816757201 0.05184165637261695 0.0446682597901401 650.3571055482048 722606.9099425666 0.011829867660829945 0.020469370278158042 1.8241503447644001e-06 5.73893937038767 -0.028919869138858578 TEFLDLDNSPLSPPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 11 TEFLDLDNSPLSPPSPR 17 0 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 TEFLDLDNSPLSPPS(1)PR;TEFLDLDNSPLS(0.02)PPS(0.98)PR;TEFLDLDNSPLSPPS(1)PR;TEFLDLDNSPLSPPS(1)PR;TEFLDLDNS(0.003)PLS(0.001)PPS(0.996)PR;TEFLDLDNS(0.003)PLS(0.038)PPS(0.959)PR;TEFLDLDNSPLSPPS(1)PR;TEFLDLDNS(0.006)PLS(0.001)PPS(0.993)PR;TEFLDLDNSPLSPPS(1)PR;TEFLDLDNSPLSPPS(1)PR;TEFLDLDNS(0.002)PLS(0.003)PPS(0.996)PR 205.0 3.1374e-17 32817500.0 99393.6 111315.7 128318.3 127955.9 148721.5 121395.6 138285.7 127763.19999999998 115910.2 94397.70000000001 True False 116218.97336691657 122366.38703616773 131377.89492186237 120786.94576162491 119580.58968122059 115029.40103125978 125186.27739423171 124409.55137629993 117605.16739444545 111511.25575821822 1.0422174208037416 1.097345610576621 1.1781581511979342 1.0831816478106793 1.072363402852341 1.0315496875101982 1.1226335542814085 1.1156681048059234 1.0546483993458042 1.0 16.766829815138315 -5.9828278884869155 24.997360953154192 1.0734538859801723 1.1093207389125521 0.1179160188571754 0.045925808726074435 573.4068198126358 834698.0215924347 0.013153170528161916 0.01950499577358355 1.0403323693242178e-06 5.9828278884869155 0.03586685293237979 TEFLDLDNSPLSPPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 TEFLDLDNSPLSPPSPR 17 0 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 TEFLDLDNS(0.004)PLS(0.034)PPS(0.962)PR;TEFLDLDNS(0.001)PLS(0.033)PPS(0.966)PR;TEFLDLDNSPLS(0.003)PPS(0.997)PR;TEFLDLDNS(0.022)PLS(0.11)PPS(0.868)PR 123.54 4.3266e-05 16169300.0 62918.9 62106.7 80683.0 69367.0 83791.0 75753.0 69969.0 69339.0 75104.0 62501.6 True False 62021.6649480869 61962.8957519743 74049.55518538677 74468.48058152835 78862.57811944436 72513.22077886788 73591.65245905361 72560.7430744647 66644.99663981875 73304.9182818529 0.8460778130823012 0.8452761043090012 1.0101580756242137 1.015872909034584 1.075815647406121 0.9891999401739868 1.003911527137896 0.9898482226727695 0.9091476834279093 1.0 16.16162237658248 -5.259708638579378 24.860437264022767 1.0020182262403117 0.8456769400839935 0.7200036953813538 0.03827480096402636 71.40588710954462 1025654.4783303845 0.01039788238079676 0.024758018374703542 5.499096759900957e-06 5.259708638579378 -0.15634128615631815 TEFLHSQNSLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 TEFLHSQNSLSPR 13 0 Q96FS4;F6RY50 Q96FS4 SIPA1 Signal-induced proliferation-associated protein 1 1 TEFLHSQNS(0.045)LS(0.955)PR;TEFLHSQNS(0.385)LS(0.615)PR;TEFLHSQNSLS(1)PR;TEFLHS(0.001)QNS(0.047)LS(0.952)PR 190.44 1.6849e-05 167838000.0 122161.0 112212.0 163333.0 219126.0 220232.0 183901.0 157029.0 201512.0 151722.0 187756.0 True False 161005.65689334975 148482.3345747417 161167.09770011384 168609.88616295173 189656.5882810351 172401.64139838202 171004.27679451922 170372.9506850941 159741.715173398 181182.71958847845 0.8886369365635034 0.819517087015752 0.8895279752184633 0.9306068842874007 1.0467697400271032 0.9515346816184185 0.9438222209210813 0.9403377489424122 0.8816608754754341 1.0 17.46708583846973 -5.714598566288653 3.0139226678001134 0.9582373810080781 0.8548901502160963 0.49107795973577295 0.043501143177545123 0.21256490929766053 3.9201827257517814 0.012839291004809834 0.023317680177210733 1.9293074161587303e-06 5.714598566288653 -0.10334723079198183 TEFLHSQNSLS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TEFLHSQNSLSPR 13 0 Q96FS4;F6RY50 Q96FS4 SIPA1 Signal-induced proliferation-associated protein 1 1 TEFLHSQNS(0.027)LS(0.973)PR;T(0.001)EFLHS(0.005)QNS(0.262)LS(0.732)PR;T(0.001)EFLHS(0.003)QNS(0.085)LS(0.912)PR 214.89 2.2347e-14 66230700.0 172992.0 191029.0 214605.0 245274.0 264078.0 253073.0 259979.0 246797.0 260862.0 193925.0 True False 202276.12885225637 209993.09665332045 219721.9970939951 231532.09296903718 212333.81159978523 239801.4063704454 235351.90703503662 240318.84025303592 264676.613247581 229082.0673905441 0.8829854346801036 0.9166719117097876 0.9591409733499927 1.0106949688659663 0.9268897125753363 1.0467925713348252 1.027369403969118 1.0490512984734641 1.155379014440072 1.0 17.805505002920903 -6.017478292700803 0.5068474232907357 1.0741649916331732 0.8689505934933381 0.6099332796830041 0.04723109469121216 1.0163840210642587 0.4585928211542823 0.036749777347461425 0.10908825078901015 9.605538284562327e-07 6.017478292700803 -0.2052143981398351 TEFLHSQNSLS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 TEFLHSQNSLSPR 13 0 Q96FS4;F6RY50 Q96FS4 SIPA1 Signal-induced proliferation-associated protein 1 1 TEFLHS(0.062)QNS(0.379)LS(0.559)PR;TEFLHS(0.001)QNS(0.364)LS(0.635)PR 79.471 0.007843000000000001 98342000.0 158201.0 124573.0 195144.0 124971.0 178989.0 170207.0 161606.0 165047.0 204716.0 145130.0 True False 155945.02472949008 124284.55887224257 179100.0135976242 134161.78423103486 168461.21892591333 162927.64338189596 169973.16793576907 172715.68615369673 181658.72832495102 170215.52712643056 0.9161621584243556 0.7301599388164397 1.0521955113095796 0.7881876964807321 0.9896936065109138 0.9571843775502255 0.9985761628521617 1.014688196015215 1.0672277164821797 1.0 17.377003120664916 -6.555356443202178 0.6826293574069094 1.035550321722515 0.8504723015569262 0.36490148271070666 0.08377092080856335 0.7845041732392498 0.8131524039979134 0.0556800486790503 0.07215716285563348 2.7838354234327357e-07 6.555356443202178 -0.18507802016558883 TEFS(ph)PAAFEQEQLGSPQVR ddPTM_PC-9_AZD4547_30min_R2 2 TEFSPAAFEQEQLGSPQVR 19 0 Q92585 Q92585 MAML1 Mastermind-like protein 1 1 T(0.222)EFS(0.755)PAAFEQEQLGS(0.023)PQVR;T(0.001)EFS(0.999)PAAFEQEQLGSPQVR 150.9 7.5048e-05 6842900.0 20308.9 17235.3 25818.1 35140.0 27236.8 26266.1 17778.2 28537.0 25310.4 27404.7 True False 26766.707748637924 22806.273670338665 25475.735124753148 27039.015907588026 23455.440461390197 24623.676614776712 19360.425359063065 24127.262365023045 26648.2560717943 26445.269794341475 1.0121548373979996 0.8623951976174791 0.9633380685041912 1.0224518833751355 0.8869427555021195 0.9311183741466487 0.7320940761665301 0.9123469925871425 1.0076757121039566 1.0 14.690722073362167 -6.312534271999825 24.985067160509963 0.8993046413714404 0.9576254244900294 0.07787741683982707 0.08213136748998195 863.6924292238554 422337.4687288841 0.026037507599342327 0.02952378468645151 4.869290980314267e-07 6.312534271999825 0.058320783118589015 TEFS(ph)PAAFEQEQLGSPQVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEFSPAAFEQEQLGSPQVR 19 0 Q92585 Q92585 MAML1 Mastermind-like protein 1 1 T(0.001)EFS(0.999)PAAFEQEQLGSPQVR 199.09 4.8166e-15 2442100.0 4495.2 4025.3 3818.0 5731.5 7545.5 4937.8 4498.7 4560.9 5263.3 4571.6 True False 5256.1485757529945 4424.905181719067 3909.035599845632 5410.382636773709 6067.0134408249705 4678.8530754998965 4072.5505682325083 4441.181207673004 5340.265805314675 5400.394891234311 0.9732896726283015 0.8193669668307743 0.7238425482904242 1.001849447260905 1.12343885271662 0.8663909158003259 0.7541208837973863 0.8223808253136707 0.9888657983109281 1.0 12.398849189492944 -5.777055560031828 24.969423793654098 0.926561298800458 0.8368863891041224 0.13012833053463868 0.11384447918039492 568.879519569807 909605.7467410675 0.03542952586735146 0.052755557816094846 1.670876842520191e-06 5.777055560031828 -0.08967490969633563 TEFS(ph)PAAFEQEQLGSPQVR ddPTM_PC-9_Lapatinib_30min_R1 1 TEFSPAAFEQEQLGSPQVR 19 0 Q92585 Q92585 MAML1 Mastermind-like protein 1 1 T(0.129)EFS(0.871)PAAFEQEQLGSPQVR 197.84 5.661600000000001e-59 0.0 7019.3 4429.6 6801.8 5514.0 6935.0 6982.2 4717.2 6283.2 8078.6 6378.6 True False 6919.20349481803 4419.343533353813 6242.582259707281 5919.517954164781 6527.096934734589 6683.58758230316 4961.433534563133 6575.140409949322 7168.702996570616 7481.132511049751 0.924887172443244 0.5907318880966715 0.8344434817170914 0.7912596048020216 0.8724744448910594 0.8933924873582169 0.6631928424252636 0.878896397067922 0.9582376713662442 1.0 12.869040969801688 -8.1248428148494 3.3442187871018096 0.9811495734025256 0.7948168426176091 0.35594726719413083 0.09763201702172018 0.2761347892841069 5.444696443247999 0.07596168893376007 0.025092327042342447 7.501656693039546e-09 8.1248428148494 -0.18633273078491652 TEFSPAAFEQEQLGS(ph)PQVR ddPTM_PC-9_AZD4547_30min_R2 2 TEFSPAAFEQEQLGSPQVR 19 0 Q92585 Q92585 MAML1 Mastermind-like protein 1 1 TEFSPAAFEQEQLGS(1)PQVR;TEFSPAAFEQEQLGS(1)PQVR 175.77 1.1932e-08 8295100.0 22218.7 24848.8 28671.2 41512.0 34031.9 24879.4 27057.5 34418.1 29147.3 31622.6 True False 29283.78442233019 32880.68865523151 28291.001154570717 31942.04975400665 29307.15811835406 23323.68718499037 29465.565082677025 29099.57349425657 30687.966772607702 30515.502399170335 0.9596363199029739 1.0775076951092728 0.9271025849254869 1.0467482834192203 0.9604022812729727 0.7643225688994227 0.9655933137603576 0.9535996856157851 1.005651697002441 1.0 14.897254722306322 -6.517986740214012 24.999483561265812 0.9284122161296456 1.0027966021185135 0.1397322046742695 0.07425556886731764 381.02385206466636 1947146.580775365 0.024279739362993272 0.024943184586670275 3.0339838157233887e-07 6.517986740214012 0.07438438598886787 TEFSPAAFEQEQLGS(ph)PQVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TEFSPAAFEQEQLGSPQVR 19 0 Q92585 Q92585 MAML1 Mastermind-like protein 1 1 TEFSPAAFEQEQLGS(1)PQVR;TEFSPAAFEQEQLGS(1)PQVR;TEFSPAAFEQEQLGS(1)PQVR 206.21 3.767499999999999e-72 4649100.0 13459.7 14358.199999999999 14350.9 12966.4 20123.1 16177.7 12827.0 13658.5 13875.8 12876.6 True False 15738.161368807296 15783.587205961974 14693.079882091324 12239.934645635985 16180.123009882034 15329.31293278679 11611.933700562022 13299.978847376991 14078.707324565441 15211.025648890485 1.0346548439325827 1.037641219618432 0.965949320002827 0.8046751697199843 1.0637101917622653 1.0077764173584793 0.7633892656941916 0.8743643692657314 0.9255593705209723 1.0 13.892829813918915 -7.210710953330698 24.998511228442727 0.8803581923507527 0.9825089964297361 0.21977587227639817 0.08658228084292713 533.4337470166347 262871.43529877835 0.03398072767433443 0.02632134028165955 6.155864427582194e-08 7.210710953330698 0.10215080407898336 TEFSPAAFEQEQLGS(ph)PQVR ddPTM_PC-9_Lapatinib_30min_R1 2 TEFSPAAFEQEQLGSPQVR 19 0 Q92585 Q92585 MAML1 Mastermind-like protein 1 1 TEFSPAAFEQEQLGS(1)PQVR;TEFSPAAFEQEQLGS(1)PQVR 166.3 8.537800000000001e-08 6382000.0 39467.7 29756.9 42807.0 29428.6 34150.6 31494.7 29902.6 28833.3 38789.0 29979.1 True False 38904.883360510255 29687.999726308502 39287.57369979853 31592.877414931754 32141.92885066287 30147.74509873157 31450.810313454498 30173.000379136694 34420.17435372189 35160.94749036023 1.106479948277175 0.8443458394984322 1.1173639080849473 0.8985217882309143 0.9141371648040754 0.8574212940933095 0.8944813083343983 0.8581395705394163 0.9789319347312404 1.0 15.101686327198747 TEGAEATPGAQK ddPTM_PC-9_Lapatinib_30min_R1 1 TEGAEATPGAQK 12 0 H3BM18;X6RHM1;Q16666-3;Q16666-2;Q16666 H3BM18 IFI16 Gamma-interferon-inducible protein 16 0 96.331 0.01989 2605300.0 17360.0 23395.0 19477.0 20846.0 22384.0 24150.0 15716.0 21973.0 20458.0 15268.0 False True 17112.443216565905 23340.83031488453 17875.676243394206 22379.084380217446 21067.417128637226 23117.160796399607 16529.69758102141 22993.945796380245 18153.80460770947 17907.05345666881 0.9556258520126892 1.3034433817581592 0.9982477735183775 1.2497357219807257 1.17648708536085 1.2909527998192514 0.9230830533353629 1.2840719916328285 1.013779550702618 1.0 14.128240345953552 -8.447360057775137 13.158544014532922 1.0000016996620529 1.1495566132579902 0.1471153213266171 0.1357657324200882 2.240144845044819 386.8313900450351 0.11965001004849048 0.030895002845538744 3.569767589742975e-09 8.447360057775137 0.1495549135959373 TEGAQVDEPVVIT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 TEGAQVDEPVVITPR 15 0 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 TEGAQVDEPVVIT(1)PR;TEGAQVDEPVVIT(1)PR 145.33 0.00013399 101351000.0 16998.5 15623.6 19377.8 25285.0 26522.0 29056.0 22795.3 27922.0 24646.0 26333.0 True False 22403.669409235463 20673.62316384997 19120.837710770415 19455.93389935581 22839.878103044073 27239.12372674099 24824.03753965252 23607.296483728973 25948.73724419377 25411.089685141396 0.8816492990592033 0.8135669670214276 0.7524603607200255 0.7656473665799645 0.8988153749423511 1.0719384357085835 0.976897797270294 0.92901551158323 1.0211579891186937 1.0 14.633170622301673 -6.511897994842792 4.866149110413809 0.9940359774696705 0.8025840948475904 0.7968990668514493 0.04670209261324177 0.0878296137135807 5.778913385547805 0.016113719909470962 0.01721830633921537 3.076819399540873e-07 6.511897994842792 -0.19145188262208013 TEGAQVDEPVVIT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TEGAQVDEPVVITPR 15 0 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 TEGAQVDEPVVIT(1)PR;TEGAQVDEPVVIT(1)PR;TEGAQVDEPVVIT(1)PR 175.19 0.00015445 61779500.0 53410.7 59711.0 69390.0 82947.0 117744.0 125353.0 146041.0 164481.0 134700.0 117364.0 True False 62452.07660058962 65638.71346374854 71044.52076304061 78299.74850780233 94672.9084323763 118779.26800865545 132206.9392347218 160163.54803202522 136669.73267263657 138641.1641470874 0.4504583972934104 0.4734431787813828 0.5124345370301994 0.5647655152746153 0.6828629073825128 0.8567388245718995 0.9535908043476943 1.1552380493725822 0.9857803309242319 1.0 17.080996148171728 -6.728143343353723 1.0578355955736622 1.0593806423989003 0.4698150068413712 0.9588354117217766 0.04948147669732704 0.08722635622827808 0.20883736408586556 0.026327607110521862 0.02466559281733617 1.8700648043991132e-07 6.728143343353723 -0.5895656355575292 down TEGAQVDEPVVIT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 TEGAQVDEPVVITPR 15 0 A0A0J9YWL0;A0A494C1M5 A0A0J9YWL0 1 TEGAQVDEPVVIT(1)PR;TEGAQVDEPVVIT(1)PR 204.78 2.0522e-12 71092000.0 127888.0 99140.0 100491.0 104573.0 215060.0 200150.0 199852.0 182962.0 253730.0 215270.0 True False 126064.29366821327 98910.4474211432 92229.01788647776 112263.64726530192 202410.59362422818 191590.05107243816 210199.35867665373 191463.08245561944 225152.25550464986 252479.13267075512 0.49930579345187764 0.3917569201654663 0.3652936260944338 0.44464525078870215 0.8016923675358997 0.7588351918266479 0.8325415112652647 0.7583323042593642 0.8917657991096603 1.0 17.945804628889455 -6.259895195662848 4.090961882796736 0.8276023381774594 0.41339733794021505 0.8854000984851178 0.0731974747209437 0.06671173108424949 2.7060628599079615 0.021943820144058046 0.026985883806420113 5.496735055610704e-07 6.259895195662848 -0.4142050002372444 TEGS(ph)SPPDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEGSSPPDSK 10 0 Q96JN0-3;A0A1P0AZG4 Q96JN0-3 LCOR Ligand-dependent corepressor 1 T(0.021)EGS(0.787)S(0.192)PPDSK 91.93700000000001 0.007752299999999999 4210800.0 34367.0 39140.0 31565.0 30816.0 40060.0 37834.0 35454.0 31876.0 34492.0 26647.0 True False 40184.65432080958 43025.5605327514 32317.629310929122 29089.479426819966 32210.530573116204 35849.91843704948 32095.540455268256 31039.28877541377 34996.38024754693 31477.890162464046 1.2765993563548284 1.3668502021796056 1.026677110318735 0.9241241797554732 1.023274762281425 1.1388920366651154 1.0196217182796048 0.9860663664309596 1.111776553858064 1.0 14.942051225536 -5.266671259715495 24.956658174331384 1.027974178434592 1.3217247897805247 0.788531420559903 0.06067569137555641 162.59534835612666 775601.9076592306 0.016312370511396574 0.03564523186181034 5.411638032296368e-06 5.266671259715495 0.2937506113459327 TEGS(ph)SPPDSK ddPTM_PC-9_Lapatinib_30min_R1 2 TEGSSPPDSK 10 0 Q96JN0-3;A0A1P0AZG4 Q96JN0-3 LCOR Ligand-dependent corepressor 1 T(0.043)EGS(0.65)S(0.308)PPDSK;T(0.004)EGS(0.886)S(0.11)PPDSK 96.229 0.0056113 12081300.0 41370.0 48005.0 44926.0 38869.0 49244.0 41724.0 42960.0 43101.0 46889.0 35264.0 True False 40780.05621367115 47893.84737191843 41232.35769937509 41727.55592318293 46347.56473742903 39939.561783394514 45184.258595105595 45103.629807936355 41607.8670569405 41359.33541367362 0.9859939915811375 1.1579936401996553 0.9969298898778592 1.008902960016799 1.12060709568622 0.9656722329776671 1.0924802863289584 1.0905308162428753 1.00600908212816 1.0 15.335925383309151 TEGSS(ph)PPDSK ddPTM_PC-9_AZD4547_30min_R2 1 TEGSSPPDSK 10 0 Q96JN0-3;A0A1P0AZG4 Q96JN0-3 LCOR Ligand-dependent corepressor 1 TEGS(0.034)S(0.965)PPDSK 102.53 0.0031803 5519600.0 28597.0 22235.0 30950.0 38502.0 35656.0 33990.0 33836.0 33718.0 31629.0 33999.0 True False 37690.251145448514 29422.02892087636 30539.58277762924 29625.95874997023 30705.779867360667 31864.5999267596 36847.33845098254 28507.657862559034 33300.84436811674 32808.7053584902 1.1487881260055595 0.8967750662329186 0.9308377896638411 0.90299078937303 0.9359034296491878 0.971223935189924 1.1230963870217825 0.8689052966602918 1.0150002569211156 1.0 15.001791045343092 -7.008453318022177 24.856021217635664 0.9988736667837901 0.9541808229146939 0.03705766643535313 0.08789266189432389 1302.3166690160522 3829320.763209861 0.031535389317238524 0.026479257946746444 9.807237258910241e-08 7.008453318022177 -0.04469284386909622 TEGSS(ph)PPDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEGSSPPDSK 10 0 Q96JN0-3;A0A1P0AZG4 Q96JN0-3 LCOR Ligand-dependent corepressor 1 T(0.001)EGS(0.084)S(0.914)PPDSK 105.2 0.0024942 4198300.0 31751.0 28330.0 27963.0 30890.0 35297.0 25532.0 27690.0 32187.0 31402.0 21750.0 True False 37125.81718916476 31142.415173552585 28629.74397026804 29159.333446731227 28380.806231634608 24193.056973482784 25067.002741760545 31342.12535494549 31861.1948432526 25693.102827094743 1.4449721171867809 1.2120924196322156 1.1142968664756385 1.134908992618095 1.1046079729111402 0.941616788610285 0.9756315891643129 1.21986532984617 1.2400680080435158 1.0 14.649093507349614 -4.269469973361442 1.1111102539554962 1.0850187077251563 2.1396012952632852 0.5837205143008253 0.09181208223614068 3.552767308788888 1.66311814591539 0.030994109319811055 5.781632754939935 5.376876069616533e-05 4.269469973361442 1.054582587538129 TEGSS(ph)PPDSK ddPTM_PC-9_Lapatinib_30min_R1 1 TEGSSPPDSK 10 0 Q96JN0-3;A0A1P0AZG4 Q96JN0-3 LCOR Ligand-dependent corepressor 1 T(0.003)EGS(0.234)S(0.763)PPDS(0.001)K 70.41199999999999 0.035844 2974900.0 24700.0 26008.0 31801.0 20000.0 25766.0 25808.0 22537.0 23205.0 30752.0 19304.0 True False 24347.773470574764 25947.78007392674 29186.444535409926 21470.866718044166 24250.494537905044 24704.25200138639 23703.85558561208 24283.189014017382 27288.385927083837 22640.670679036837 1.0753998331471049 1.1460694094169206 1.2891157222844052 0.9483317443384837 1.0711031877849253 1.091144884866871 1.0469590729730305 1.0725472473084185 1.205281694784349 1.0 14.466629074953744 -5.76263789976058 24.999997615569335 1.0661607595088674 1.167782404731155 0.2808246253342245 0.0789946227171057 44.49021135572161 928059.1459032011 0.021970705250042955 0.0347530733364298 1.727277438044113e-06 5.76263789976058 0.10162164522228756 TEGT(ph)PPPPGQPAK ddPTM_PC-9_AZD4547_30min_R2 2 TEGTPPPPGQPAK 13 0 F8VWT9;J3KPF0;Q9Y4D8-2;Q9Y4D8-4;Q9Y4D8;A0A494C150 F8VWT9 HECTD4 Probable E3 ubiquitin-protein ligase HECTD4 1 T(0.197)EGT(0.803)PPPPGQPAK;T(0.014)EGT(0.986)PPPPGQPAK 113.69 0.00077392 17784600.0 49664.0 44387.0 50406.0 70669.0 56700.0 55316.0 51690.0 57807.0 54209.0 56633.0 True False 65456.11892462682 58734.22971490621 49737.5835053047 54377.35387516615 48828.18371324181 51857.08177548202 56290.30986320153 48874.256422710416 57074.37707013308 54650.29590774364 1.1977267064596453 1.0747284848019258 0.9101063897122863 0.9950056623108089 0.8934660444596628 0.9488893136648902 1.0300092420034914 0.8943090903883872 1.0443562312358123 1.0 15.737941687038186 -4.959427976858152 3.0354612062484807 0.961340078484102 1.1997302971194839 0.6683375470437082 0.05175857255572347 0.15162454500941397 2.584998119872302 0.012619959373983351 0.07173393966967072 1.09792335414093e-05 4.959427976858152 0.2383902186353819 TEGT(ph)PPPPGQPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TEGTPPPPGQPAK 13 0 F8VWT9;J3KPF0;Q9Y4D8-2;Q9Y4D8-4;Q9Y4D8;A0A494C150 F8VWT9 HECTD4 Probable E3 ubiquitin-protein ligase HECTD4 1 TEGT(1)PPPPGQPAK;T(0.015)EGT(0.985)PPPPGQPAK;T(0.012)EGT(0.988)PPPPGQPAK;T(0.059)EGT(0.941)PPPPGQPAK 124.3 0.0003799 35453600.0 123156.0 112300.0 110936.0 140599.0 136515.0 130881.0 127244.0 111188.0 117522.0 111754.0 True False 144003.87835812362 123448.40183515567 113581.1349671228 132721.69385810813 109765.86573112739 124017.36995716748 115190.5271532169 108269.43281342392 119240.53692021947 132014.1155558229 1.090821824255837 0.9351151679151676 0.8603711390172847 1.0053598685209235 0.8314706747000269 0.9394250715918787 0.8725622003997591 0.8201352738498754 0.9032408119251304 1.0 17.010332671850968 -4.778376780760083 3.4256314834326855 0.8985892607125451 1.1159367667042153 0.4594141009339394 0.06019463986031208 0.25455124371836374 4.809991812184819 0.014540889276391886 0.14660164599469794 1.6658013865526632e-05 4.778376780760083 0.2173475059916702 TEGT(ph)PPPPGQPAK ddPTM_PC-9_Lapatinib_30min_R1 2 TEGTPPPPGQPAK 13 0 F8VWT9;J3KPF0;Q9Y4D8-2;Q9Y4D8-4;Q9Y4D8;A0A494C150 F8VWT9 HECTD4 Probable E3 ubiquitin-protein ligase HECTD4 1 T(0.011)EGT(0.989)PPPPGQPAK;T(0.002)EGT(0.998)PPPPGQPAK 113.54 0.00081567 16296200.0 62274.0 54299.0 58535.0 52138.0 57577.0 51985.0 49225.0 48907.0 56319.0 36955.0 True False 61385.96134034707 54173.27400162065 53722.47825163426 55972.402447269385 54190.434060737374 49761.72273295377 51773.629640225176 51179.397763781424 49975.761154638254 43342.62251055774 1.4162955027789146 1.2498845446748106 1.239483795392125 1.2913939952211055 1.2502804611681546 1.1481013342197375 1.1945200045893334 1.1808099002619128 1.1530396238129053 1.0 15.403498828055133 -1.52287874597458 0.05338879576413693 0.6137416380579339 2.3711037082885063 0.8275876318375143 0.04264437247243112 177.0096019003371 0.71371317601883 5.265150116211268 25.078441798898265 0.029999999952043426 1.52287874597458 1.7573620702305723 TEIIILAT(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 TEIIILATR 9 0 P23396;P23396-2;E9PL09;F2Z2S8;H0YCJ7;E9PPU1;H0YF32;E9PQ96;E9PJH4;E9PK82;H0YEU2 P23396 RPS3 40S ribosomal protein S3 1 TEIIILAT(1)R 78.77 0.029787 0.0 7659.6 7384.4 8157.7 7044.4 7169.5 7082.1 5485.4 6249.3 7807.0 5706.0 True False 7550.372699401393 7367.3018754961795 7487.005395632638 7562.468675429517 6747.804105779331 6779.215092181441 5769.407171731663 6539.665292191284 6927.693448645407 6692.274497232918 1.1282222064446514 1.1008666602875252 1.1187534819033977 1.130029660103811 1.0082975688712967 1.0129911878217892 0.8620996006839173 0.9771962125724618 1.0351777189518794 1.0 12.708280906319713 -6.431996557378534 2.3478105528903277 0.9684819155124924 1.1193012387388626 0.6961534916595065 0.04433026544000677 0.17280155793974172 1.876831347896147 0.01597310640344536 0.018187848276778874 3.6983111139355997e-07 6.431996557378534 0.15081932322637015 TEIKEEEDQPSTSATQS(ph)SPAPGQSK ddPTM_PC-9_AZD4547_30min_R2 4 TEIKEEEDQPSTSATQSSPAPGQSK 25 1 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 1 TEIKEEEDQPST(0.001)S(0.003)AT(0.085)QS(0.455)S(0.455)PAPGQSK;TEIKEEEDQPSTSAT(0.028)QS(0.595)S(0.376)PAPGQS(0.001)K;TEIKEEEDQPS(0.001)T(0.001)S(0.006)AT(0.026)QS(0.483)S(0.483)PAPGQSK;TEIKEEEDQPSTSAT(0.097)QS(0.451)S(0.451)PAPGQSK 126.15 1.5811e-09 107997700.0 346996.0 357193.0 319869.0 289574.0 340615.0 401208.0 387071.0 368875.0 390760.0 373078.0 True False 457333.51003483 472648.6519601793 315627.32806130796 222817.18817370213 293326.4866928726 376120.40033584565 421519.56914411386 311873.84465423354 411414.77584764897 360016.65277610475 1.270312099477373 1.3128521925737715 0.8767020237188788 0.6189080045479805 0.8147581075236903 1.0447305629769184 1.1708335319873604 0.866276163197897 1.1427659600610443 1.0 18.45770411521913 -5.258023511347837 24.81593278900357 0.932872476152031 1.2915821881713134 0.44963534859740206 0.15450527610165335 248.17004123807908 1802908.005372039 0.04366435694556104 0.10609765646452538 5.520475523402038e-06 5.258023511347837 0.3587097120192825 TEIKEEEDQPSTSATQS(ph)SPAPGQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TEIKEEEDQPSTSATQSSPAPGQSK 25 1 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 1 TEIKEEEDQPSTSAT(0.018)QS(0.491)S(0.491)PAPGQS(0.001)K;TEIKEEEDQPST(0.002)S(0.001)AT(0.014)QS(0.492)S(0.492)PAPGQSK;TEIKEEEDQPS(0.034)T(0.034)S(0.081)AT(0.081)QS(0.376)S(0.376)PAPGQS(0.019)K 116.35 3.7553e-09 84653000.0 273744.0 342510.0 245754.0 315890.0 317860.0 221555.0 309156.0 223853.0 214380.0 225965.0 True False 320083.4525095505 376512.1292302684 251613.7073872355 298191.7074291978 255577.61477710222 209936.26577471313 279870.505584388 217977.0959418592 217514.9019328859 266930.6657620446 1.199125816420392 1.4105240705686106 0.9426182138680784 1.1171129648139448 0.9574681651786571 0.7864823817652365 1.04847640785446 0.8166056729359635 0.8148741595946477 1.0 18.02610553039044 -5.539489832348979 0.9625819018579221 0.8915507708567213 1.3409783961921615 0.5762495901652376 0.12037901558307806 0.5461791858043957 0.829354986071782 0.044480740094471415 0.2003301359578202 2.8874213783652194e-06 5.539489832348979 0.44942762533544023 TEIKEEEDQPSTSATQS(ph)SPAPGQSK ddPTM_PC-9_Lapatinib_30min_R1 2 TEIKEEEDQPSTSATQSSPAPGQSK 25 1 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 1 TEIKEEEDQPSTSAT(0.013)QS(0.493)S(0.493)PAPGQSK;TEIKEEEDQPSTS(0.001)AT(0.006)QS(0.497)S(0.497)PAPGQSK 144.95 3.009e-09 47761500.0 212750.0 295833.0 256262.0 326644.0 342735.0 301486.0 278015.0 306037.0 303891.0 286889.0 True False 209716.1459864286 295148.0168644261 235193.12755992688 350666.4894124414 322576.0011429357 288592.14657819207 292409.25636215764 320256.5962629961 269663.5954659026 336477.38139443676 0.6232696685801538 0.8771704524127814 0.6989864417787445 1.04216957454674 0.9586855431592738 0.8576866159092249 0.869030943923627 0.9517923461475534 0.8014315682925163 1.0 18.360150002015835 -4.1084332624357645 0.9327942755039822 0.9102295786097783 2.5864548091104086e-17 0.4445377251804751 0.09311261195237619 6.057411414152144 1.7030255711955096 0.030243082381237487 7.546431620497397 7.79052521515851e-05 4.1084332624357645 -0.9102295786097783 TEIKEEEDQPSTSATQSS(ph)PAPGQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEIKEEEDQPSTSATQSSPAPGQSK 25 1 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 1 TEIKEEEDQPSTSAT(0.001)QS(0.121)S(0.878)PAPGQSK 175.93 4.6223e-15 18424000.0 49039.0 59758.0 45965.0 52151.0 45646.0 34631.0 51004.0 35393.0 31254.0 30525.0 True False 57340.334135600424 65690.3793131364 47060.979923233244 49229.148545823205 36701.99397255269 32814.889395608734 46172.53188301751 34463.971251983305 31711.030623241077 36058.94086423297 1.5901835373228215 1.8217501052088576 1.3051126515452716 1.3652411126321744 1.0178333886938307 0.9100347544638498 1.280473879054397 0.9557677077023711 0.8794221311889776 1.0 15.138069401600927 -5.722345600369811 1.1700405614412501 1.0065210905476834 1.7310501899508912 0.7826263885409745 0.14000569761072126 0.2413692273972954 0.6360433624094363 0.04983512845734309 0.14265363520517735 1.8951971718524706e-06 5.722345600369811 0.7245290994032079 TEIKEEEDQPSTSATQSS(ph)PAPGQSK ddPTM_PC-9_Lapatinib_30min_R1 2 TEIKEEEDQPSTSATQSSPAPGQSK 25 1 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 1 TEIKEEEDQPSTSAT(0.003)QS(0.228)S(0.762)PAPGQS(0.007)K;TEIKEEEDQPSTSAT(0.023)QS(0.136)S(0.84)PAPGQSK 136.44 1.044e-07 57559900.0 147297.0 245242.0 193526.0 227507.0 221782.0 214504.0 225484.0 232967.0 221278.0 195675.0 True False 145196.51776903868 244674.15721662345 177615.03931196287 244238.6237211042 208737.21880018833 205330.1639532466 237158.4582183148 243791.49730784635 196355.34147935917 229497.16302945113 0.6326723862395012 1.066131511112513 0.7739313068944984 1.0642337382173275 0.9095416084659892 0.8946958700613515 1.0333829625069506 1.062285450894924 0.8555894063673506 1.0 17.808116794051323 -4.749737878428715 24.995665595347955 0.9599201996123843 0.6326716568651451 0.5152147265725722 0.09587127123132409 422.57912961074663 902618.132446048 0.022571252042920827 0.35743650392917053 1.7793530273827988e-05 4.749737878428715 -0.32724854274723914 TEIKPVAT(ph)EQLLS(ph)T(ph)FLT(ph)VGNNT(ph)CFYGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEIKPVATEQLLSTFLTVGNNTCFYGK 27 1 O75063 O75063 FAM20B Glycosaminoglycan xylosylkinase 5 T(0.139)EIKPVAT(0.873)EQLLS(0.992)T(0.992)FLT(0.992)VGNNT(0.884)CFY(0.128)GK 40.937 0.018300999999999998 3582000.0 5720.5 9270.7 9026.6 6672.8 9769.2 6280.0 8157.0 8789.0 7118.4 7127.6 True False 6688.867664974861 10191.03382807815 9241.828377571132 6298.944649509489 7854.9953887889815 5950.665744691835 7384.309908434115 8558.298062715263 7222.493133310277 8419.777457949443 0.794423332253234 1.2103685494034517 1.0976333310146527 0.7481129615323036 0.9329219718714502 0.7067485779061271 0.8770196059590978 1.0164518130624742 0.8578009536928125 1.0 13.039566386771378 -5.7449555001526695 24.978304660171393 0.8729295534969495 1.0517644618396067 0.22274941830779627 0.1331425030790057 320.1824629288364 485174.1042284666 0.03540971273638269 0.061106915099048885 1.7990552453141546e-06 5.7449555001526695 0.17883490834265725 TEIMS(ph)PLYQDEAPK ddPTM_PC-9_AZD4547_30min_R2 3 TEIMSPLYQDEAPK 14 0 Q8IY81 Q8IY81 FTSJ3 pre-rRNA processing protein FTSJ3 1 T(0.024)EIMS(0.976)PLYQDEAPK;TEIMS(1)PLYQDEAPK;TEIMS(1)PLYQDEAPK 155.37 0.00019875 39479000.0 202857.0 224079.0 200003.0 163174.0 178793.0 222091.0 215053.0 230079.0 197045.0 194890.0 True False 267361.30631227896 296508.1546463256 197350.8295403615 125556.75531316915 153970.67814182802 208203.61466119366 234192.30038713623 194525.57723944823 207460.3964246594 188066.96041989952 1.4216282632278308 1.5766094904937478 1.0493647002096156 0.6676172945680462 0.8187013699698007 1.1070717269866794 1.2452601980924882 1.0343421130704111 1.1031198460455782 1.0 17.5208868930741 -5.301710034563543 6.494773794120077 0.9966619524471202 1.4992377422010073 0.6205700049256748 0.15518071854851415 0.13255202612255115 16.30837648536072 0.046006782227241624 0.09932661767224288 4.9921768893333834e-06 5.301710034563543 0.5025757897538871 TEIMS(ph)PLYQDEAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TEIMSPLYQDEAPK 14 0 Q8IY81 Q8IY81 FTSJ3 pre-rRNA processing protein FTSJ3 1 T(0.074)EIMS(0.477)PLY(0.449)QDEAPK;T(0.001)EIMS(0.821)PLY(0.179)QDEAPK;TEIMS(0.992)PLY(0.008)QDEAPK;TEIMS(0.956)PLY(0.044)QDEAPK;TEIMS(1)PLYQDEAPK 182.02 2.0620999999999998e-05 43728400.0 218250.0 220766.0 193418.0 203351.0 229239.0 166868.0 223578.0 144778.0 171845.0 161552.0 True False 255195.41436601052 242682.18948833377 198029.81866185015 191957.9027428373 184321.26355593026 158117.14832567464 202399.0732754545 140977.73090497125 174357.90802620054 190840.09875507132 1.337221139743458 1.271651980225591 1.0376740525375974 1.0058572804932395 0.9658413758865873 0.8285321028292169 1.0605688982335848 0.7387217457160583 0.9136335034597504 1.0 17.542004812431166 -5.177393323265921 0.9155748542609213 0.9015467403532325 1.465485674910646 0.7526558566102466 0.08561974806623111 0.5908816928453662 0.5855956316128725 0.030374589093526458 0.2939627914756207 6.64670917475953e-06 5.177393323265921 0.5639389345574135 TEIMS(ph)PLYQDEAPK ddPTM_PC-9_Lapatinib_30min_R1 5 TEIMSPLYQDEAPK 14 0 Q8IY81 Q8IY81 FTSJ3 pre-rRNA processing protein FTSJ3 1 T(0.003)EIMS(0.989)PLY(0.008)QDEAPK;T(0.019)EIMS(0.981)PLYQDEAPK;T(0.002)EIMS(0.995)PLY(0.004)QDEAPK;T(0.004)EIMS(0.991)PLY(0.005)QDEAPK;T(0.002)EIMS(0.981)PLY(0.017)QDEAPK 147.56 0.00010355 44964900.0 186929.0 201362.0 204018.0 198661.0 243671.0 214761.0 222999.0 206753.0 223447.0 214449.0 True False 184263.35818141975 200895.75866064418 187244.42757225424 213271.1926536684 229338.75085561836 205576.1726623427 234544.79707751278 216359.4991689349 198280.04585877675 251516.22391466895 0.7326102281335702 0.7987387673599989 0.7444626221638092 0.8479420903123299 0.9118248806622722 0.8173475629631265 0.9325235303989217 0.8602208469952954 0.7883389897187966 1.0 17.94029193771342 -1.5228787452803376 0.07871522111561279 1.0931832421469667 0.19278144087385388 0.5437472794427136 0.05454985773589324 166.82907294416168 0.9627148962093132 1.6946217680077984 16.371243111746256 0.029999999999999995 1.5228787452803376 -0.9004018012731129 TEIMSPLY(ph)QDEAPK ddPTM_PC-9_AZD4547_30min_R2 1 TEIMSPLYQDEAPK 14 0 Q8IY81 Q8IY81 FTSJ3 pre-rRNA processing protein FTSJ3 1 TEIMS(0.018)PLY(0.982)QDEAPK 118.03 0.00012733 17163000.0 173130.0 180040.0 167700.0 143790.0 142990.0 190230.0 179320.0 186840.0 176270.0 153450.0 True False 228181.73867229084 238234.40912590854 165476.18842676666 110641.4370333546 123138.30668706262 178334.88802787542 195279.1326111297 157968.17115607476 185587.27233766278 148077.762206545 1.540958853457101 1.6088466328496327 1.1174951995557145 0.7471846912369416 0.8315786574036971 1.204332678792961 1.318760695064707 1.0667919936265258 1.2533095420418223 1.0 17.175995472502976 -5.292154337963045 5.771409903441092 1.0618538010840664 1.5770077781358445 0.5933759004256508 0.1682345230315204 0.12492227040984626 13.23657707948216 0.04946326463535695 0.11026284372357896 5.103236108335711e-06 5.292154337963045 0.5151539770517781 TEIMSPLY(ph)QDEAPK ddPTM_PC-9_Lapatinib_30min_R1 1 TEIMSPLYQDEAPK 14 0 Q8IY81 Q8IY81 FTSJ3 pre-rRNA processing protein FTSJ3 1 T(0.004)EIMS(0.052)PLY(0.944)QDEAPK 108.43 0.00071905 10306000.0 39401.0 53378.0 41505.0 48926.0 51995.0 51688.0 57388.0 46703.0 52388.0 47537.0 True False 38839.13451474152 53254.40652053451 38092.61911393318 52524.18125235147 48936.75632610311 49477.424730612955 60359.269838359454 48872.9918776838 46487.51176990336 55753.70711092904 0.6966197680356242 0.955172476954369 0.68323024759848 0.9420751367769676 0.8777309861878287 0.8874284293270647 1.0826054977522312 0.8765873053148702 0.8338012695265372 1.0 15.766780113779616 -5.794790308859121 24.997388717279144 0.926043312871125 0.7960238585539269 0.333127859950189 0.0964105286247252 230.86107321291715 173035.43448484378 0.02646864624357176 0.03926206579081768 1.6040196752892528e-06 5.794790308859121 -0.13001945431719808 TEKEPDATPPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEKEPDATPPSPR 13 1 A0A494C0S2;A0A090HNM7;A0A1W2PS85;R4GMW8;P28715 A0A494C0S2 ERCC5-201;BIVM-ERCC5;ERCC5 DNA repair protein complementing XP-G cells 1 TEKEPDAT(0.009)PPS(0.991)PR 66.387 0.01772 11178000.0 20368.0 26915.0 21027.0 29549.0 31535.0 27180.0 24557.0 25519.0 19646.0 18804.0 True False 23815.90011366279 29586.943324961776 21528.36342534156 27893.465329150546 25355.943125891637 25754.632952344604 22230.783182716263 24849.15328961551 19933.28558341955 22213.016347617897 1.0721596626482826 1.3319642349308698 0.9691778499793992 1.2557261423949664 1.1414903194185415 1.1594387970234625 1.0007998389241843 1.1186753253472626 0.8973695994941803 1.0 14.439117692032534 -7.577563822170435 1.1012056977398135 0.972106839272129 1.1625181744558197 0.33185203374992955 0.10409220781137772 0.5870396085634589 1.3117954567313854 0.07880866847582112 0.035052052183664355 2.645063958199668e-08 7.577563822170435 0.1904113351836907 TEKEPDATPPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 TEKEPDATPPSPR 13 1 A0A494C0S2;A0A090HNM7;A0A1W2PS85;R4GMW8;P28715 A0A494C0S2 ERCC5-201;BIVM-ERCC5;ERCC5 DNA repair protein complementing XP-G cells 1 TEKEPDAT(0.003)PPS(0.997)PR 62.813 0.022622999999999997 9764000.0 23822.0 45066.0 43465.0 42212.0 51043.0 45469.0 39700.0 47448.0 47521.0 36214.0 True False 23482.29391158024 44961.652445846776 39891.47547975198 45316.41129510402 48040.75109439912 43524.396863415895 41755.471746408126 49652.607297440016 42168.684561685484 42473.541647878206 0.5528687507685932 1.0585802525863266 0.9392076556852137 1.0669327194514242 1.1310747639713024 1.0247414078215957 0.9830937126123563 1.1690244178147184 0.9928224236933171 1.0 15.374276792091521 -4.760413239021135 24.998475150371206 1.0440783640685212 0.5528681698901137 0.8308260133710033 0.06601023825545983 9.651203198406508 235005.39237698365 0.016249729344442475 0.09650342411730202 1.7361480664044532e-05 4.760413239021135 -0.4912101941784075 TEKGESSSPS(ph)PSAEK ddPTM_PC-9_AZD4547_30min_R2 1 TEKGESSSPSPSAEK 15 1 E9PHV5;P28290-3;P28290;P28290-2 E9PHV5 SSFA2 Sperm-specific antigen 2 1 TEKGESSS(0.005)PS(0.53)PS(0.464)AEK 62.658 0.01993 11647000.0 13536.0 12102.0 13853.0 22559.0 24369.0 23368.0 24011.0 25276.0 24929.0 27967.0 True False 17840.16643370951 16013.734832491384 13669.300168610604 17358.371083075628 20985.784989558902 21906.795265916993 26147.932484529545 21370.17498469785 26246.696046437824 26987.883842492298 0.6610435459789645 0.593367561752946 0.5064976657076148 0.6431912625822463 0.7776002413541176 0.8117270473583722 0.9688767239823282 0.7918432993642357 0.9725362758940189 1.0 14.720024237064374 -6.531217009426717 1.38980749471896 0.9159537533987835 0.5836298331852026 0.8248240107406606 0.06803851225806183 0.1672142271014837 0.6661892671791637 0.02836519893731946 0.03133690824733957 2.9429507248567006e-07 6.531217009426717 -0.3323239202135809 TEKGESSSPSPS(ph)AEK ddPTM_PC-9_AZD4547_30min_R2 1 TEKGESSSPSPSAEK 15 1 E9PHV5;P28290-3;P28290;P28290-2 E9PHV5 SSFA2 Sperm-specific antigen 2 1 TEKGESSSPS(0.006)PS(0.994)AEK 86.45299999999999 0.002582 6227600.0 10643.0 14992.0 16378.0 19645.0 20475.0 25181.0 20985.0 29219.0 22361.0 24314.0 True False 14027.252611847682 19837.870815461134 16160.81701880491 15116.14876222442 17632.399674226217 23606.42808931254 22852.624346668308 24703.874935823962 23542.95680911373 23462.774260605624 0.5978514073418703 0.8455040565586159 0.68878542832589 0.6442609298596321 0.7515053198048834 1.0061226275764035 0.9739949799985176 1.0528965867988667 1.003417436813631 1.0 14.51808598862704 -6.723299759623936 4.232239862092923 1.0106777547938708 0.7040515692628858 0.8556069964717987 0.06222551401444853 0.0757652801527039 2.939716577222901 0.02124213655781707 0.020442467863871685 1.891037932027865e-07 6.723299759623936 -0.306626185530985 TEKGESSSPSPS(ph)AEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEKGESSSPSPSAEK 15 1 E9PHV5;P28290-3;P28290;P28290-2 E9PHV5 SSFA2 Sperm-specific antigen 2 1 TEKGESSSPS(0.257)PS(0.743)AEK 96.15299999999999 0.0042523000000000005 0.0 10701.0 7926.8 9741.3 13588.0 20067.0 16079.0 16891.0 15966.0 18443.0 16690.0 True False 12512.467945615952 8713.720317603835 9973.569536085972 12826.708412890372 16135.015402164807 15235.788934538221 15290.962199749994 15546.909417375327 18712.69398427194 19715.764882032687 0.6346427856328708 0.44196714506089474 0.5058677457233757 0.6505813236076664 0.8183814068947902 0.7727718922243212 0.7755703261446838 0.7885521819923654 0.9491234094257808 1.0 14.267062061088758 -6.5072606408647475 0.3571648160345868 0.9912595642250648 0.40798205206685534 0.8004278981195452 0.07535386765889561 0.9333778386335082 0.22223145218916396 0.09019804883437677 0.21034302986436237 3.109849407758853e-07 6.5072606408647475 -0.5832775121582094 TELGSQT(ph)PESSR ddPTM_PC-9_AZD4547_30min_R2 1 TELGSQTPESSR 12 0 H0YID1;F8VUX5;H0YIQ8;F8VXI8;F8VX10;Q9H9L4-4;Q9H9L4 H0YID1 KANSL2 KAT8 regulatory NSL complex subunit 2 1 TELGS(0.042)QT(0.953)PES(0.002)S(0.002)R 76.868 0.044467 4414400.0 14906.0 8868.5 19384.0 23350.0 22450.0 21033.0 18157.0 27713.0 15767.0 22880.0 True False 19645.797935939263 11735.069192030223 19126.955494719386 17967.018253903814 19333.205015207735 19717.803185040728 19772.93782523024 23430.592631386757 16600.41143103153 22078.978164130007 0.8897965200154171 0.5315041803472261 0.8662971335237543 0.8137613126993996 0.8756385767262039 0.8930577782387912 0.8955549336677995 1.0612172563969746 0.7518650232645695 1.0 14.430385783927518 -5.966676999087761 1.0800182044069382 0.9248570912503542 0.7184122424191381 0.2770877685867206 0.11574317108669496 0.6400343113827084 1.5105062197770904 0.04364715213479783 0.09350257787265884 1.0797494734013846e-06 5.966676999087761 -0.20644484883121605 TELGSQT(ph)PESSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TELGSQTPESSR 12 0 H0YID1;F8VUX5;H0YIQ8;F8VXI8;F8VX10;Q9H9L4-4;Q9H9L4 H0YID1 KANSL2 KAT8 regulatory NSL complex subunit 2 1 TELGS(0.032)QT(0.765)PES(0.156)S(0.047)R 85.976 0.022894 0.0 12587.0 19862.0 18176.0 18848.0 19629.0 16358.0 14797.0 15639.0 15559.0 12553.0 True False 14717.730495417984 21833.76809661493 18609.384772863847 17792.00766604046 15782.838357955501 15500.157683386778 13395.321038997128 15228.492820890191 15786.5209402639 14828.75953050668 0.9925125877953391 1.472393429247881 1.254952225408971 1.1998311544156874 1.0643397598758026 1.0452767577422004 0.9033338905684869 1.026956623685289 1.0645881004265292 1.0 13.85611029669211 -6.281746037165691 1.960311817914705 1.0032833924605506 1.261928425499939 0.4552001505617791 0.11522051643683434 0.28075553473859105 2.1204466955524226 0.038847482609801684 0.04996308775301768 5.227017604959734e-07 6.281746037165691 0.25864503303938835 TEMDKS(ph)PFNSPSPQDSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEMDKSPFNSPSPQDSPR 18 1 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 TEMDKS(0.999)PFNS(0.001)PSPQDSPR 113.14 0.0037484000000000003 0.0 7134.7 6347.9 7521.9 9093.6 11068.0 8688.0 10206.0 10855.0 8584.8 6774.0 True False 8342.463793251669 6978.0775601904115 7701.250622964605 8584.115073848976 8899.304852302797 8232.385985650106 9239.213794958761 10570.067751823199 8710.33645915403 8002.072577045506 1.0425378816461375 0.8720337753755828 0.9624069950397814 1.0727364681086622 1.1121249859481486 1.0287817195341704 1.1546025990144204 1.3209162563888965 1.0885100547750877 1.0 12.966157998332955 -6.11996106869095 1.0566249501199263 1.148796390393476 0.9425117104025076 0.3507171106512985 0.09192810230275422 0.5267267308304351 1.2144706408585997 0.03947710589879007 0.07079650504386209 7.586455789826401e-07 6.11996106869095 -0.20628467999096833 TEMDKS(ph)PFNSPSPQDSPR ddPTM_PC-9_Lapatinib_30min_R1 2 TEMDKSPFNSPSPQDSPR 18 1 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 TEMDKS(0.999)PFNS(0.001)PSPQDSPR;T(0.001)EMDKS(0.699)PFNS(0.291)PS(0.009)PQDSPR 127.2 5.0227e-05 16886000.0 44876.0 35885.0 48520.0 40916.0 39371.0 37187.0 32453.2 37676.3 50645.0 22952.5 True False 44236.06001074953 35801.91048726783 44530.87289261629 43925.0991317748 37055.275186364175 35596.59869713096 34133.467901272845 39426.878442095345 44940.82678450705 26919.80904271618 1.6432531129977939 1.329946673487081 1.6542046350312138 1.6317017354051335 1.376505870735008 1.3223198812683443 1.2679684260430701 1.4646046849564582 1.6694333423091983 1.0 14.716380555689971 -6.282573819940239 20.465103178795115 1.3678692295452388 1.5543905628377355 0.2516149604856791 0.17943450756478976 131.62617085648017 127456.08663960564 0.05512706107968922 0.0626537907899422 5.217064187697047e-07 6.282573819940239 0.18652133329249665 TEMDKSPFNSPS(ph)PQDSPR ddPTM_PC-9_AZD4547_30min_R2 2 TEMDKSPFNSPSPQDSPR 18 1 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 TEMDKSPFNSPS(0.996)PQDS(0.004)PR;TEMDKS(0.001)PFNS(0.036)PS(0.793)PQDS(0.17)PR 126.34 9.503200000000001e-05 26345200.0 44672.0 38496.0 60666.0 81634.0 68283.0 59709.0 47339.0 57064.0 48429.0 56092.0 True False 58876.766764677275 50939.07916968994 59861.52920153976 62814.54253272744 58803.0841003755 55975.38679102353 51552.07929220546 48246.07000026894 50988.85807023694 54128.23615307604 1.0877274219350557 0.9410814537838055 1.1059205593223067 1.160476435165674 1.0863661607978297 1.0341254540924574 0.9524064140278811 0.8913290627802432 0.9420011013482713 1.0 15.724093756061807 -7.180862037773579 2.8673155268283472 0.934989801819163 1.0743113618143472 0.5313914213961727 0.05733236601150776 0.22518019838305145 3.613813423179806 0.026579098954652897 0.019155044511974684 6.593833281248317e-08 7.180862037773579 0.13932155999518414 TEMDKSPFNSPS(ph)PQDSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TEMDKSPFNSPSPQDSPR 18 1 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 T(0.001)EMDKS(0.021)PFNS(0.26)PS(0.711)PQDS(0.008)PR;TEMDKS(0.104)PFNS(0.25)PS(0.645)PQDS(0.001)PR 67.785 0.019237999999999998 34351900.0 74673.0 51483.0 63801.0 78042.0 82035.0 80216.0 80801.0 77750.0 83096.0 55424.0 True False 87313.66404102228 56593.892000706204 65322.25780663993 73669.55975557782 65960.83064317476 76009.3317478026 73146.94433141919 75709.14488293462 84311.12179781291 65471.93246385738 1.3336045043304967 0.8643992909778225 0.9977139111129784 1.1252082683865456 1.0074672941658973 1.1609452919350167 1.1172259864453926 1.1563603216497162 1.2877445131828875 1.0 15.998588941565522 -6.7757411116447885 24.811587758380746 1.152525943315847 1.0540278489769865 0.07976115180890297 0.12938616713820975 477.24835972497056 827956.2267202296 0.043930661614433826 0.038925265133780196 1.6759416280117992e-07 6.7757411116447885 -0.09849809433886048 TEMDKSPFNSPS(ph)PQDSPR ddPTM_PC-9_Lapatinib_30min_R1 2 TEMDKSPFNSPSPQDSPR 18 1 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 TEMDKS(0.011)PFNS(0.093)PS(0.883)PQDS(0.014)PR;TEMDKSPFNS(0.014)PS(0.59)PQDS(0.395)PR 67.785 0.019237999999999998 60063000.0 79809.0 56136.0 66546.0 41145.0 56863.0 62426.0 53618.0 43925.0 68837.0 43392.0 True False 78670.9090248219 56006.02054098558 61074.84475498845 44170.94055569638 53518.430136959374 59756.18550211359 56394.07768511111 45965.91585609623 61083.85217425439 50892.24938379439 1.5458328129994794 1.100482317427682 1.2000814563019984 0.8679306002489591 1.0516027643690915 1.1741706492765427 1.1081073909668584 0.903200711555366 1.2002584463029318 1.0 15.635158337874337 -4.028317326383862 1.4461783002227504 1.0549546703904586 4.1098965594720065 0.6296129298594828 0.1100580840559799 5.801729196283336 2.211451603834595 0.030444436498923855 43.461414615879086 9.368772077676024e-05 4.028317326383862 3.054941889081548 TEMDKSPFNSPSPQDS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 TEMDKSPFNSPSPQDSPR 18 1 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 TEMDKSPFNS(0.01)PS(0.341)PQDS(0.649)PR;TEMDKSPFNS(0.055)PS(0.373)PQDS(0.571)PR 84.948 0.0028843000000000002 25019000.0 97570.0 70592.0 76278.0 64344.0 71382.0 68749.0 57297.0 57367.0 72096.0 52029.0 True False 96178.63390785315 70428.54856115962 70006.71728159473 69076.0724052916 67183.45110241164 65808.76553174642 60263.558303625854 60032.48024852978 63975.78927546289 61022.143325715304 1.5761267740873102 1.1541474081832255 1.1472346506729998 1.1319837134626227 1.100968393453658 1.0784407420840951 0.9875686925967123 0.9837819023841388 1.048402854910914 1.0 15.897045233197183 -1.522878745280439 0.7933129582334423 1.0387759436108597 123.22055385845933 0.904114391112517 0.050674051169730824 145.1476807398459 0.5198664403292373 0.01951986577917241 31850.341404939198 0.029999999999992987 1.522878745280439 122.18177791484847 TEMGPPPSPAS(ph)TCSDASSIASSASMPYKR ddPTM_PC-9_AZD4547_30min_R2 1 TEMGPPPSPASTCSDASSIASSASMPYKR 29 1 E7EMW7;O95071-2;O95071 E7EMW7 UBR5 E3 ubiquitin-protein ligase UBR5 1 T(0.006)EMGPPPS(0.15)PAS(0.397)T(0.397)CS(0.04)DAS(0.004)S(0.003)IAS(0.001)S(0.001)AS(0.001)MPYKR 51.46 0.017116 0.0 8317.2 8861.6 11445.0 13941.0 12266.0 12205.0 9334.4 14587.0 10014.0 11141.0 True False 10961.896591492965 11725.938901967085 11293.23182196984 10727.117836302916 10563.07762657186 11441.819420597263 10165.14351687113 12332.914325913418 10543.319596013813 10750.956981056486 1.019620542692912 1.0906879194688015 1.0504396810320105 0.997782602535237 0.982524406449056 1.0642605528752553 0.9455105749918284 1.1471457236452893 0.9806866137211285 1.0 13.392177464515358 -5.598007056067394 7.704765412506547 1.02065661571516 1.0589372798739758 0.0827835790650372 0.05486796482566995 0.5835662336268739 51.252371990562054 0.014256649761360658 0.02480149225648978 2.5234397733279403e-06 5.598007056067394 0.038280664158815814 TENNDHINLK ddPTM_PC-9_AZD4547_30min_R2 2 TENNDHINLK 10 0 P61956-2;P61956 P61956-2 SUMO2 Small ubiquitin-related modifier 2 0 ; 83.86200000000001 0.010879999999999999 15938200.0 219980.0 187322.0 255240.0 307380.0 279980.0 296000.0 232540.0 300880.0 233400.0 292890.0 False True 289929.0641317536 247870.1732186371 251855.35082914654 236518.28997365944 241109.60980658617 277491.0732074392 253235.60951032865 254385.9095345736 245737.0475044564 282636.0102487774 1.0258036966929898 0.8769943115191187 0.8910943464262123 0.8368299912154684 0.8530746297839419 0.9817965975502924 0.8959778666824146 0.900047765713442 0.8694470576773201 1.0 18.108585763525646 -6.727877406054867 24.999799073617147 0.9211148377664972 0.8920172445188095 0.05738419291050845 0.060280947152149204 675.123690431659 502887.5682615585 0.020067990343535343 0.020066776613693497 1.8712102766531967e-07 6.727877406054867 -0.02909759324768768 TENNDHINLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TENNDHINLK 10 0 P61956-2;P61956 P61956-2 SUMO2 Small ubiquitin-related modifier 2 0 77.533 0.018158 8482500.0 97224.0 121100.0 113910.0 128400.0 144830.0 120570.0 133180.0 111130.0 111270.0 82169.0 False True 113682.10293846954 133122.00767798178 116626.04640608089 121206.16427841643 116451.60117085428 114247.09694864556 120564.22626029828 108212.95525196785 112897.1132478414 97065.58925055376 1.1711885109461795 1.3714644778424636 1.2015179355171486 1.2487037395461436 1.1997207462498345 1.177009255604903 1.242090293699118 1.1148436442562522 1.1631013021146144 1.0 16.56667231560347 -9.269941008702947 0.2253729088419567 0.9099448216036559 1.2934380710281437 0.6176061029178693 0.056099020473444915 4.002928206016992 0.41478254110876206 0.4361717641878762 0.14103959793266146 5.371047476861097e-10 9.269941008702947 0.3834932494244878 TENNDHINLK ddPTM_PC-9_Lapatinib_30min_R1 4 TENNDHINLK 10 0 P61956-2;P61956 P61956-2 SUMO2 Small ubiquitin-related modifier 2 0 ;;; 86.014 0.009682600000000001 34249500.0 396739.0 366200.0 449090.0 405439.0 440463.0 376137.0 390584.0 393362.0 410352.0 376939.0 False True 391081.429106977 365352.086399261 412167.55373753095 435256.33656485606 414555.832323576 360050.49732817255 410806.5283778099 411639.03455858264 364133.83656187245 442092.40391035326 0.8846146770399607 0.8264156614492442 0.9323108700621546 0.9845370169561126 0.9377130858996593 0.8144236230785431 0.9292322707745789 0.931115375241901 0.8236600161890836 1.0 18.753988420366404 TEPAAEAEAASGPS(ph)ESPSPPAAEELPGSHAEPPVPAQGEAPGEQAR ddPTM_PC-9_AZD4547_30min_R2 1 TEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQAR 46 0 P55884;P55884-2 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 1 TEPAAEAEAAS(0.009)GPS(0.636)ES(0.262)PS(0.083)PPAAEELPGS(0.01)HAEPPVPAQGEAPGEQAR 83.274 1.5212e-13 5972100.0 6887.1 4481.8 7464.3 11746.0 6225.9 6764.6 8844.9 10013.0 5577.1 7148.2 True False 9077.054539420864 5930.454203624179 7365.31850491302 9038.141173890974 5361.541251856649 6341.608492631892 9632.078965158275 8465.720925849806 5871.894120124692 6897.943693742748 1.315907311283916 0.8597423329221726 1.0677556721134498 1.3102660118970872 0.7772666014540249 0.9193476743488761 1.3963696128595122 1.227281825093646 0.8512528342977336 1.0 12.751950637135883 -10.570637435972067 14.96758205624442 1.000018064135113 1.0803999811617655 0.012849166830506409 0.21187235822595668 0.0 0.0 0.2054292692845873 0.04982391622669455 2.687587199949978e-11 10.570637435972067 0.08038191702665243 TEPAAEAEAASGPS(ph)ESPSPPAAEELPGSHAEPPVPAQGEAPGEQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQAR 46 0 P55884;P55884-2 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 1 TEPAAEAEAAS(0.15)GPS(0.386)ES(0.222)PS(0.222)PPAAEELPGS(0.02)HAEPPVPAQGEAPGEQAR 70.346 1.7751e-09 8397400.0 18472.0 17906.0 22569.0 28767.0 25673.0 22655.0 20663.0 24958.0 28180.0 16067.0 True False 21598.944761369763 19683.589343368596 23107.130553409123 27155.278253872348 20642.55994517253 21466.931918151826 18705.651052834874 24302.878945186872 28592.079188677733 18979.81991369798 1.1379952422931858 1.0370798792017357 1.2174578398782598 1.4307447793155317 1.0876056800873295 1.131039810480966 0.9855547174783659 1.2804588797835312 1.5064462844582875 1.0 14.212178683244224 -7.967206538240042 24.973182462915073 1.2999665923002954 1.151870496287764 0.08431808028439303 0.16133214681020158 351.5197717269015 267692.342067071 0.08808415550120231 0.042313796495262554 1.078433727509243e-08 7.967206538240042 -0.1480960960125315 TEPAAEAEAASGPS(ph)ESPSPPAAEELPGSHAEPPVPAQGEAPGEQAR ddPTM_PC-9_Lapatinib_30min_R1 2 TEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQAR 46 0 P55884;P55884-2 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 1 TEPAAEAEAAS(0.004)GPS(0.352)ES(0.315)PS(0.315)PPAAEELPGS(0.015)HAEPPVPAQGEAPGEQAR;TEPAAEAEAAS(0.022)GPS(0.302)ES(0.302)PS(0.302)PPAAEELPGS(0.073)HAEPPVPAQGEAPGEQAR 98.245 1.2357000000000001e-23 51050000.0 86501.0 68032.0 85460.0 78286.0 72043.0 81846.0 72651.0 71019.0 86145.0 62173.0 True False 85267.4798776593 67874.47608387365 78433.80868513987 84043.4135944402 67805.5723819877 78345.63737234467 76412.51329592685 74318.80200760617 76442.44295293436 72919.52020968492 1.1693368199964425 0.930813530981774 1.0756215682659216 1.15255028218463 0.9298686029064409 1.0744124090100509 1.047902030570108 1.0191893994076966 1.0483124783750501 1.0 16.154017448422582 -6.250936792127131 24.97810312491956 1.0250279268484825 1.0708143950291236 0.14874897490653294 0.07016465225458517 1870.3197099686015 4448139.427641517 0.02047038231854062 0.026124422459636466 5.611296377421837e-07 6.250936792127131 0.04578646818064103 TEPAAEAEAASGPSES(ph)PSPPAAEELPGSHAEPPVPAQGEAPGEQAR ddPTM_PC-9_Lapatinib_30min_R1 1 TEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQAR 46 0 P55884;P55884-2 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 1 TEPAAEAEAAS(0.004)GPS(0.288)ES(0.319)PS(0.319)PPAAEELPGS(0.069)HAEPPVPAQGEAPGEQAR 85.86399999999999 4.592e-17 59601000.0 58578.0 45870.0 68478.0 50857.0 54120.0 55612.0 48838.0 46726.0 54338.0 37981.0 True False 57742.666978110465 45763.790833244384 62848.00317272414 54597.19343397865 50936.768004013866 53233.60439790375 51366.59267383075 48897.060541649465 48217.88223549304 44545.96524349867 1.2962490915277183 1.027338628382813 1.4108573656263197 1.2256372296691207 1.1434653559661705 1.1950263981690914 1.1531143705843825 1.0976765297231004 1.0824298445868847 1.0 15.443007144926206 -7.9047934847068975 0.619701971714468 1.0026745368469043 1.2310031168352962 0.4032434421872123 0.09151712606162597 0.770199255183151 0.6323851136253618 0.08723673665094354 0.045200042688141616 1.2451065428851847e-08 7.9047934847068975 0.22832857998839184 TEPAAEAEAASGPSESPS(ph)PPAAEELPGSHAEPPVPAQGEAPGEQAR ddPTM_PC-9_AZD4547_30min_R2 2 TEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQAR 46 0 P55884;P55884-2 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 1 TEPAAEAEAAS(0.007)GPS(0.093)ES(0.181)PS(0.556)PPAAEELPGS(0.163)HAEPPVPAQGEAPGEQAR;TEPAAEAEAAS(0.001)GPS(0.031)ES(0.14)PS(0.79)PPAAEELPGS(0.038)HAEPPVPAQGEAPGEQAR 91.176 1.5390999999999998e-17 133306000.0 96260.0 77450.0 118827.0 187368.0 147287.0 130600.0 114660.0 150500.0 102806.0 129611.0 True False 126868.67766761786 102484.19788270185 117251.27633981753 144173.2024067432 126838.74240868134 122433.5613543631 124864.51787414754 127243.68314594972 108240.11527739117 125073.35834051797 1.0143541306551636 0.8193927087468452 0.9374600466119695 1.1527091326213934 1.014114789045298 0.9788940105136708 0.9983302561861188 1.0173524148885724 0.8654130401032527 1.0 16.932414990692777 -5.537350631338716 24.98575587472384 1.0068962155983194 0.9072616035042042 0.17995808056489782 0.0784443398868067 318.8195930436765 550441.0861052254 0.02105732035291543 0.0364909393779911 2.9016790133151713e-06 5.537350631338716 -0.09963461209411528 TEPAAEAEAASGPSESPS(ph)PPAAEELPGSHAEPPVPAQGEAPGEQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQAR 46 0 P55884;P55884-2 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 1 TEPAAEAEAAS(0.016)GPS(0.165)ES(0.149)PS(0.641)PPAAEELPGS(0.029)HAEPPVPAQGEAPGEQAR;TEPAAEAEAAS(0.036)GPS(0.185)ES(0.17)PS(0.44)PPAAEELPGS(0.17)HAEPPVPAQGEAPGEQAR 91.76100000000001 1.203e-17 114337000.0 25872.4 29668.3 43264.6 28764.9 47994.6 45898.1 34559.3 45875.9 36352.4 24908.1 True False 30252.086316807225 32613.57275303599 44296.19214590919 27153.295910064044 38590.40266211885 43491.122837012765 31285.592916335296 44671.70623453396 36883.98507801589 29423.74135758888 1.0281522648378196 1.10841012217586 1.505457501395704 0.9228362763276109 1.3115396235008618 1.4780962865484022 1.0632771861375208 1.518219783529071 1.2535450413923275 1.0 14.844693082799516 -5.018057888488237 23.582307133322253 1.2688917430988538 1.0482164830736322 0.12770659699418097 0.19967118174245274 562.8735095466794 735085.7880283087 0.048108304242184076 0.13373615005400089 9.592727584868799e-06 5.018057888488237 -0.22067526002522153 TEPNS(ph)QEDKNDGGK ddPTM_PC-9_AZD4547_30min_R2 1 TEPNSQEDKNDGGK 14 1 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 T(0.001)EPNS(0.999)QEDKNDGGK 70.96 0.01236 21012000.0 33633.0 42813.0 257500.0 297090.0 234050.0 96512.0 51020.0 299780.0 67419.0 84256.0 True False 44327.59439014125 56651.464996153816 254085.38175248879 228600.49049474436 201556.19749707665 90477.08938309552 55560.68116116355 253455.88925908902 70982.63070138359 81306.22308553052 0.5451931316931373 0.6967666538459055 3.1250422428945233 2.8115989381804987 2.4789762683361705 1.1127941496915636 0.6833509054124454 3.117300000425118 0.8730282628761765 1.0 16.31107815830783 TEPS(ph)SPLSDPSDIIR ddPTM_PC-9_Lapatinib_30min_R1 1 TEPSSPLSDPSDIIR 15 0 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 T(0.002)EPS(0.761)S(0.237)PLS(0.001)DPSDIIR 104.9 0.0011024000000000001 2049900.0 7249.7 8908.3 11491.0 8537.7 11562.0 12193.0 8301.3 8894.8 10334.0 9043.9 True False 7146.317948567842 8887.673378674324 10546.25433654274 9165.590938932288 10881.945891766598 11671.53381327124 8731.100695427143 9308.084880063858 9170.076098155718 10607.126064760741 0.6737280112385501 0.8378964598338445 0.9942612421266274 0.8640974834250761 1.0259089809367752 1.1003483641103033 0.8231353754184014 0.8775312769202781 0.8645203273882803 1.0 13.37274619944378 -4.874343419021007 2.7556683003175375 0.9406009130249814 0.6498690799577934 0.4998183991918367 0.08323682184721778 0.31870126345321115 3.8227830973199786 0.02281228116931334 0.19375334723201743 1.3355390193806387e-05 4.874343419021007 -0.290731833067188 TEPSS(ph)PLSDPSDIIR ddPTM_PC-9_AZD4547_30min_R2 2 TEPSSPLSDPSDIIR 15 0 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 TEPS(0.025)S(0.975)PLSDPSDIIR;TEPS(0.205)S(0.794)PLS(0.001)DPSDIIR 272.74 8.989099999999998e-75 29589000.0 96649.0 115256.0 127281.0 146429.0 137266.0 144247.0 137344.0 165147.0 140356.0 135613.0 True False 127381.37157591511 152510.2480460772 125593.1707760719 112672.05635549815 118208.98528363065 135227.21228700507 149567.34992941702 139627.3258505258 147774.9316175469 130865.23014738435 0.9733782719248985 1.1653993033467758 0.9597138264657854 0.8609777878249516 0.9032879486056009 1.0333318646573129 1.1429112970723374 1.066955108650887 1.1292146237095855 1.0 16.99772231001475 -6.999670115584829 24.898564675804053 1.0900315322609349 0.9755490979427675 0.2923622884556947 0.0822293195374365 15.249973648221888 1150904.7554715117 0.03170987220785883 0.027685566114667402 1.0007598754959986e-07 6.999670115584829 -0.1144824343181674 TEPSS(ph)PLSDPSDIIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TEPSSPLSDPSDIIR 15 0 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 TEPS(0.207)S(0.79)PLS(0.004)DPSDIIR;TEPS(0.206)S(0.793)PLS(0.001)DPSDIIR;TEPS(0.292)S(0.707)PLS(0.001)DPSDIIR;TEPS(0.034)S(0.966)PLSDPSDIIR;TEPS(0.185)S(0.408)PLS(0.408)DPSDIIR 275.76 6.164999999999998e-75 28323800.0 74466.59999999999 92742.2 103655.3 97647.8 114591.6 80457.9 109672.7 82102.0 82220.7 74585.90000000001 True False 87072.32459760808 101949.03270415282 106126.83546691433 92176.91034443902 92138.19858268334 76238.54608596193 99283.70789441267 79946.9094942598 83423.02219121774 88107.73324834066 0.9882483794264213 1.1570951713943092 1.2045121529546672 1.0461841083191752 1.0457447398287094 0.8652877934230334 1.1268444236849378 0.9073767596417588 0.9468297403144105 1.0 16.426981030129895 -6.254175432065712 2.403774411982684 0.9739711065201777 1.1181516854097788 0.3371108247657111 0.0846940192541955 0.32713987039111964 3.7248206102980177 0.027592972834538997 0.035303870228584416 5.569607207285274e-07 6.254175432065712 0.14418057888960112 TEPSS(ph)PLSDPSDIIR ddPTM_PC-9_Lapatinib_30min_R1 2 TEPSSPLSDPSDIIR 15 0 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 TEPS(0.039)S(0.955)PLS(0.006)DPSDIIR;TEPS(0.368)S(0.632)PLSDPSDIIR 266.07 1.3427999999999998e-61 33091000.0 41932.0 67542.0 76521.0 68698.0 89284.0 83305.0 87043.0 84788.0 89617.0 74336.0 True False 41334.04199061298 67385.6106487681 70229.73875960211 73750.2800898101 84032.49065909775 79742.23934343985 91549.66063533006 88727.56001381196 79523.3897511536 87184.87855350628 0.47409645659190597 0.7729047945787163 0.8055265996213022 0.8459067823848464 0.9638424925662553 0.9146338294719445 1.050063521957481 1.0176943695500926 0.9121236511483957 1.0 16.411790313546803 -4.412140581994133 0.6143913719074122 0.9889261611147904 6.2797750860046914e-15 0.8893188373349354 0.053052108643185394 1.6513514811505707 0.3412690963744849 0.025369462901362636 1.2743999167818607 3.871323091326962e-05 4.412140581994133 -0.988926161114784 down TEPT(ph)SPTPSAFK ddPTM_PC-9_AZD4547_30min_R2 2 TEPTSPTPSAFK 12 0 Q86XN7-2;Q86XN7 Q86XN7-2 PROSER1 Proline and serine-rich protein 1 1 TEPT(0.987)S(0.01)PT(0.001)PS(0.002)AFK;T(0.001)EPT(0.611)S(0.367)PT(0.018)PS(0.003)AFK 140.63 0.00018583 18465200.0 80461.0 89596.0 117762.0 120688.0 108887.0 124915.0 124433.0 155237.0 115229.0 119353.0 True False 106045.92430723285 118556.15485472615 116200.3989356761 92865.24621101252 93769.91957643321 117104.04530306513 135507.29594133823 131248.68864138052 121319.76969533424 115174.48779822589 0.9207414448676745 1.029361251099502 1.0089074512686134 0.8063004922904722 0.8141552992248481 1.0167533413147851 1.1765391670656558 1.1395639012635768 1.0533562771980742 1.0 16.813461656467474 -6.998089289083041 24.62904291865155 1.1029453284997892 0.9206937594960379 0.5197628994335762 0.07990014526762883 43.437379797226825 559894.6746757267 0.03077567509137213 0.026950420055911133 1.0044092668110274e-07 6.998089289083041 -0.18225156900375128 TEPTS(ph)PLVELQEISTVEVTNTFKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEPTSPLVELQEISTVEVTNTFKK 24 1 Q5JWZ0;Q5JXL1;Q9BVI0 Q5JWZ0 PHF20 PHD finger protein 20 1 T(0.016)EPT(0.221)S(0.763)PLVELQEISTVEVTNTFKK 85.397 0.00017104 0.0 2188.8 653.58 798.07 1115.9 1111.0 2597.5 2296.8 2855.6 2694.1 830.74 True False 2559.3206092294354 718.463103040257 817.0990154973296 1053.3797407966126 893.3075253802317 2461.282527362585 2079.230476608003 2780.643525758299 2733.4961157635435 981.346585865778 2.607968118594425 0.7321196337646643 0.8326304154576096 1.0734023595417967 0.910287495005778 2.5080665310422985 2.118752443382308 2.8334979362109043 2.7854543492928734 1.0 9.938618938250672 -6.764675756725391 24.999940779700083 2.355597907267188 1.172631965704179 0.34493738491539994 0.6912790571162378 83.62710167146183 645985.9806356855 0.23165165186998582 0.21277285579926866 1.7191914525681117e-07 6.764675756725391 -1.182965941563009 TEPTS(ph)PTPSAFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEPTSPTPSAFK 12 0 Q86XN7-2;Q86XN7 Q86XN7-2 PROSER1 Proline and serine-rich protein 1 1 TEPT(0.003)S(0.722)PT(0.273)PS(0.002)AFK 122.18 0.00041276 10467000.0 25024.0 30469.0 36951.0 38230.0 49112.0 41185.0 43450.0 37873.0 36398.0 33291.0 True False 29260.068953471044 33493.760957394064 37832.05197744788 36088.09704333229 39488.856153441906 39025.18609795114 39334.10144924145 36878.87387976049 36930.25189174919 39326.394768589 0.7440313083782043 0.8516865365992407 0.962001531034452 0.9176558709662543 1.0041311029350362 0.9923408013266845 1.0001959671283827 0.9377639139506525 0.9390703650578803 1.0 15.263210313405105 -4.728664732466106 1.1748279081490758 0.9739643606425885 0.6098164301830125 0.8675862378325182 0.028422056445308968 0.5985368401573035 0.6433513474324192 0.009075085946887076 0.2769022760667935 1.8678210586926006e-05 4.728664732466106 -0.36414793045957605 TEPTS(ph)PTPSAFK ddPTM_PC-9_Lapatinib_30min_R1 2 TEPTSPTPSAFK 12 0 Q86XN7-2;Q86XN7 Q86XN7-2 PROSER1 Proline and serine-rich protein 1 1 TEPT(0.004)S(0.943)PT(0.041)PS(0.012)AFK;TEPT(0.012)S(0.619)PT(0.369)PSAFK 140.45 7.5475e-05 45485000.0 396740.0 631380.0 624400.0 653520.0 862670.0 864230.0 849550.0 773400.0 819630.0 735540.0 True False 391082.41484679445 629918.0784018723 573064.2422537017 701582.0408788105 811929.4466744763 827268.897518528 893535.5421199254 809334.9874355097 727314.6383134674 862677.1089545562 0.4533357971219748 0.7301898611465938 0.6642859029239517 0.8132614550640269 0.9411742101960038 0.9589554294781997 1.0357705482677815 0.9381667590743312 0.8430902254898949 1.0 19.7184611491627 -5.20674166505411 0.7020008606553154 0.966975445669195 0.37032068072214536 0.8335984330269153 0.06959483735956953 0.7605193824377124 0.41671974512781185 0.03332433110694326 0.3294890795243887 6.21238460709566e-06 5.20674166505411 -0.5966547649470497 down TEPTSPT(ph)PSAFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEPTSPTPSAFK 12 0 Q86XN7-2;Q86XN7 Q86XN7-2 PROSER1 Proline and serine-rich protein 1 1 TEPTS(0.336)PT(0.453)PS(0.211)AFK 113.95 0.001935 9904600.0 48105.0 58670.0 60445.0 68113.0 86653.0 71990.0 100310.0 88878.0 63369.0 71251.0 True False 56248.22638294133 64494.369863477885 61886.23803893907 64296.84943532549 69673.96669376515 68214.71766884788 90807.91061849048 86545.04667402498 64295.65174263021 84168.24227739446 0.66828324865765 0.7662553965535229 0.7352682717904423 0.763908663120485 0.8277940088631016 0.8104567212421008 1.0788856718572497 1.028238731525333 0.7638944333746466 1.0 16.36098836876235 -6.910518029730536 2.124348509402017 0.9675070783526194 0.7452367475239572 0.5711805425637362 0.08697657133153414 0.23527656243736209 2.1616803930961845 0.0365573377903924 0.030429453099054943 1.22880217181122e-07 6.910518029730536 -0.2222703308286622 TEPVS(ph)GEENSPDISATR ddPTM_PC-9_AZD4547_30min_R2 1 TEPVSGEENSPDISATR 17 0 Q86T82-2;Q86T82 Q86T82-2;Q86T82 USP37 Ubiquitin carboxyl-terminal hydrolase 37 1 TEPVS(1)GEENSPDISATR 100.77 0.001127 4309900.0 8253.6 7390.2 15238.0 18045.0 16096.0 14586.0 14145.0 13792.0 11506.0 13262.0 True False 10878.073114455146 9778.93762676233 15035.934163667682 13885.004042470853 13861.348237184126 13673.935114201682 15403.87759750409 11660.76330863083 12114.183670035443 12797.70141663864 0.850002102745753 0.7641167197453496 1.1748933401524007 1.0849607746293082 1.0831123329039862 1.0684680528976733 1.2036440838881497 0.9111607568426588 0.9465905849534404 1.0 13.643597091915003 -5.251878053668997 24.991362265183675 1.0632084213320205 0.8070593839317235 0.5670746759788792 0.08803089093717736 485.01415595208834 1267721.9255961985 0.023364897110692853 0.060136585581686886 5.599147989106282e-06 5.251878053668997 -0.25614903740029704 TEQELPRPQS(ph)PSDLDSLDGR ddPTM_PC-9_AZD4547_30min_R2 3 TEQELPRPQSPSDLDSLDGR 20 1 P54259 P54259 ATN1 Atrophin-1 1 T(0.01)EQELPRPQS(0.875)PS(0.112)DLDS(0.003)LDGR;TEQELPRPQS(0.674)PS(0.321)DLDS(0.005)LDGR;TEQELPRPQS(0.861)PS(0.121)DLDS(0.018)LDGR 77.445 0.00092969 36317000.0 32442.8 32051.9 47582.3 65533.7 50075.4 52197.1 39019.7 61636.9 36252.5 48832.0 True False 42758.935547839144 42412.049865933746 46951.327612277506 50425.91795057202 43123.29507432222 48933.207085527 42492.37770882502 52112.333380057105 38168.73313905439 47122.40654330402 0.9074013549911764 0.9000399804911999 0.99636947805564 1.0701048959422768 0.9151335476615197 1.0384275905042946 0.9017446439153283 1.1058928692906949 0.8099911685108552 1.0 15.524125599096296 -5.257363197022115 23.972078939519562 0.9837248628838207 0.9037206511148661 0.11900124716041083 0.08212168061253342 364.61757782510233 2144278.6211232394 0.0193338486675291 0.047300001863663364 5.528875403674031e-06 5.257363197022115 -0.08000421176895456 TEQELPRPQS(ph)PSDLDSLDGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TEQELPRPQSPSDLDSLDGR 20 1 P54259 P54259 ATN1 Atrophin-1 1 T(0.003)EQELPRPQS(0.859)PS(0.137)DLDS(0.002)LDGR;T(0.003)EQELPRPQS(0.72)PS(0.265)DLDS(0.012)LDGR 67.64399999999999 0.0025698 7695400.0 13229.8 17962.8 17489.5 18042.4 19868.0 24699.0 24019.6 21387.2 18864.9 18106.800000000003 True False 15469.343839539284 19746.028071990462 17906.51600929812 17031.542822250023 15975.008023631353 23403.74095989547 21744.289601155328 20825.808661611518 19140.763473615563 21389.419506650076 0.7232241078225516 0.9231680207988499 0.8371669929485883 0.7962601704527247 0.7468649637108966 1.094173731672294 1.0165909175045598 0.9736500167822073 0.8948706376844218 1.0 14.384609708885444 -6.755203107857517 24.999996054489078 0.9955060564385403 0.8131471020254598 0.6616338365475862 0.06800846186163256 99.91863568324246 400553.90508885204 0.023439842007725167 0.02288713395319569 1.7571016725435957e-07 6.755203107857517 -0.18235895441308048 TEQELPRPQS(ph)PSDLDSLDGR ddPTM_PC-9_Lapatinib_30min_R1 4 TEQELPRPQSPSDLDSLDGR 20 1 P54259 P54259 ATN1 Atrophin-1 1 TEQELPRPQS(0.729)PS(0.256)DLDS(0.014)LDGR;TEQELPRPQS(0.814)PS(0.186)DLDSLDGR;T(0.001)EQELPRPQS(0.989)PS(0.01)DLDSLDGR;TEQELPRPQS(0.881)PS(0.118)DLDS(0.001)LDGR 93.029 0.00029282 33789200.0 43479.3 36521.2 45439.4 40570.2 42889.7 39068.5 32981.0 39452.1 41991.3 33237.4 True False 42859.27720887291 36436.63740525585 41703.54793315637 43553.86784621981 40367.01217039457 37397.631328121664 34688.59480272761 41285.18859297196 37261.79760600792 38982.44030394836 1.0994508520938306 0.9346935984806818 1.069803419385533 1.1172688909834214 1.0355178345852805 0.9593455678128449 0.8898518033314132 1.0590714247509632 0.955861082976733 1.0 15.25053678579961 -6.685920934169471 5.4648909321522146 0.9714518292902241 1.0507517546051803 0.3002793444083196 0.06020640371257256 0.2825993146042418 14.755561191365764 0.02062654773111059 0.020423519134161818 2.0610050970541697e-07 6.685920934169471 0.07929992531495622 TEQS(ph)VTPEQQK ddPTM_PC-9_AZD4547_30min_R2 1 TEQSVTPEQQK 11 0 F6U236;Q9BY11 F6U236 PACSIN1 Protein kinase C and casein kinase substrate in neurons protein 1 1 T(0.336)EQS(0.426)VT(0.238)PEQQK 86.699 0.010776 4519500.0 47584.0 43561.0 51074.0 59080.0 60214.0 48584.0 45330.0 42932.0 51466.0 53213.0 True False 62714.72219131454 57641.24136821657 50396.72538884123 45460.01877690094 51854.32546929703 45546.03479969664 49364.28218415414 36297.84587921538 54186.38769007857 51350.02906677663 1.2213181439441647 1.1225162364223538 0.9814351871798221 0.8852968460404141 1.0098207617733692 0.8869719380385869 0.9613291965221639 0.7068709899270538 1.055235774445492 1.0 15.648077472733283 -5.145694139306957 1.720805658117927 0.9185140446021756 1.239388306249175 0.5334323537719842 0.0911243890893744 0.35950598420250685 1.6832979864779318 0.024915108823375835 0.1499109871160029 7.149997018331451e-06 5.145694139306957 0.3208742616469995 TEQS(ph)VTPEQQK ddPTM_PC-9_Lapatinib_30min_R1 1 TEQSVTPEQQK 11 0 F6U236;Q9BY11 F6U236 PACSIN1 Protein kinase C and casein kinase substrate in neurons protein 1 1 TEQS(0.868)VT(0.132)PEQQK 104.17 0.0027155 3377900.0 29097.0 40296.0 38253.0 34257.0 57834.0 40592.0 56306.0 65465.0 52329.0 52932.0 True False 28682.071444263704 40202.69708777885 35107.986000850186 36776.37405800197 54432.317826018814 38855.97478457362 59221.2491726261 68506.74289173215 46435.15697120089 62081.22567254344 0.46200878177810967 0.6475822062507897 0.5655169597654599 0.5923912367965215 0.8767919324455687 0.625889298473667 0.9539317004628306 1.1035017777046001 0.7479742300213266 1.0 15.921869420551367 -6.625536252519118 0.7155938862631475 0.9723220700587968 0.529343845103766 0.629777588171444 0.12354369712800803 0.46382461932603936 0.5283484268311102 0.08460270979856717 0.09881606556924498 2.3684474185442756e-07 6.625536252519118 -0.4429782249550308 TEQSVT(ph)PEQQK ddPTM_PC-9_AZD4547_30min_R2 1 TEQSVTPEQQK 11 0 F6U236;Q9BY11 F6U236 PACSIN1 Protein kinase C and casein kinase substrate in neurons protein 1 1 TEQS(0.014)VT(0.986)PEQQK 86.49799999999999 0.020898 0.0 48159.0 34486.0 42321.0 53884.0 45361.0 46810.0 39329.0 43616.0 55441.0 46351.0 True False 63472.56023057155 45632.92508951391 41759.795887949826 41461.8762995012 39063.408137854705 43882.96330013584 42829.20480963153 36876.14939597175 58371.49807495524 44728.265598146405 1.4190704553766988 1.0202256778631944 0.9336332480032582 0.9269725920519357 0.8733494942284 0.9811013843996312 0.957542266324908 0.8244484534070541 1.3050248493734178 1.0 15.448899196432853 -4.761423447669058 3.788731954145328 0.9636175626894775 1.475879692327714 0.540295063579062 0.12166542120387719 0.19673551647323084 4.9353894319073675 0.02900744234817125 0.2914829228602275 1.732114320613461e-05 4.761423447669058 0.5122621296382365 TEQSVT(ph)PEQQK ddPTM_PC-9_Lapatinib_30min_R1 1 TEQSVTPEQQK 11 0 F6U236;Q9BY11 F6U236 PACSIN1 Protein kinase C and casein kinase substrate in neurons protein 1 1 TEQS(0.004)VT(0.996)PEQQK 114.7 0.0016022000000000002 0.0 35784.0 40110.0 35889.0 30156.0 60278.0 42524.0 68995.0 75040.0 51570.0 50921.0 True False 35273.713598018105 40017.127759351046 32938.34495554629 32373.772837466997 56732.5665511077 40705.34764828563 72567.22350487218 78526.63234698812 45761.643543825245 59722.62700203247 0.5906256199483267 0.6700496908481469 0.5515220379442676 0.5420688014337558 0.9499342108507215 0.6815732946057506 1.2150708558483636 1.314855629915873 0.7662362799658478 1.0 15.86599000582983 -6.770206483800966 1.360398476270368 1.0833801581771856 0.5991901820275288 0.5537290698786458 0.1762462244846407 0.3032816685622684 1.174097396104924 0.08301937794963973 0.0743983372225489 1.6974364203366475e-07 6.770206483800966 -0.48418997614965675 TES(ph)FHSYR ddPTM_PC-9_Lapatinib_30min_R1 1 TESFHSYR 8 0 Q9Y597-3;Q9Y597-2;Q9Y597 Q9Y597-3 KCTD3 BTB/POZ domain-containing protein KCTD3 1 TES(1)FHSYR 92.538 0.0044768 4822200.0 27833.0 42806.0 40395.0 34886.0 47428.0 40308.0 41929.0 40031.0 45328.0 39929.0 True False 27436.09631605293 42706.88533699279 37073.87902920928 37451.632816284444 44638.378287035666 38584.12080253732 44099.87845982739 41890.9864003503 40222.68331499922 46830.67444795185 0.5858573817156044 0.9119425641511465 0.7916580204373015 0.7997243955542135 0.9531867480714434 0.8239070066227672 0.94168787829098 0.8945202454196645 0.8588960929807486 1.0 15.515166195201392 -4.757530042006429 24.98797374744496 0.8791016710423268 0.5858569570838376 0.6538110341139481 0.06537596783059725 69.99547907489232 447338.8738619972 0.01574795983824197 0.11604089346374807 1.7477123614990967e-05 4.757530042006429 -0.2932447139584893 TES(ph)GEETDLISPPQEEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TESGEETDLISPPQEEVK 18 0 A0A5F9UY30;A0A5H1ZRP2;O43493;O43493-5;O43493-3;O43493-7 A0A5F9UY30 TGOLN2 Trans-Golgi network integral membrane protein 2 1 T(0.097)ES(0.903)GEETDLISPPQEEVK;T(0.016)ES(0.984)GEETDLISPPQEEVK 258.13 2.2063e-65 3847000.0 15173.3 16385.1 15234.4 16381.2 21759.6 14632.400000000001 19261.1 13487.900000000001 12828.900000000001 16573.0 True False 17741.84000366457 18011.70444264652 15597.645872783738 15463.414472566958 17495.962582595585 13865.051185131966 17436.54916971195 13133.856916611348 13016.498392605672 19577.55370820419 0.906233754640635 0.9200181345996522 0.7967106669842705 0.7898542740856762 0.8936746052834839 0.708211628060643 0.8906398332292647 0.6708630257061924 0.664868480843496 1.0 14.25691288537307 -4.949135658314607 0.7466334074078281 0.7815624740482956 0.991688952860559 0.12467858064120807 0.102635348743423 4.19675469216207 2.0887674554366527 0.041891247864611805 0.711150649082418 1.1242537418037247e-05 4.949135658314607 0.21012647881226343 TES(ph)GEETDLISPPQEEVK ddPTM_PC-9_Lapatinib_30min_R1 3 TESGEETDLISPPQEEVK 18 0 A0A5F9UY30;A0A5H1ZRP2;O43493;O43493-5;O43493-3;O43493-7 A0A5F9UY30 TGOLN2 Trans-Golgi network integral membrane protein 2 1 T(0.008)ES(0.992)GEETDLISPPQEEVK;T(0.028)ES(0.932)GEET(0.04)DLISPPQEEVK;T(0.012)ES(0.987)GEET(0.001)DLISPPQEEVK 249.16 1.1517999999999996e-131 3553100.0 43293.2 54951.7 38953.4 44460.0 40016.8 31158.1 39767.0 38071.299999999996 43392.7 31760.2 True False 42675.831028999484 54824.46271487242 35750.80181647235 47729.73671421218 37663.09050005583 29825.54069607864 41825.94067857463 39840.231584113746 38505.357180611696 37249.908252193636 1.1456627151957164 1.471801281863394 0.959755432803435 1.2813383697770957 1.0110921682025313 0.8006876283869027 1.1228468106659435 1.0695390526704873 1.033703409949852 1.0 15.184949251721074 -5.698417316025878 1.198233511124845 1.0138908405525364 1.2888631343610326 0.29904550604187474 0.14624911503069477 0.6478448463109022 1.7842992781303622 0.05073337164615448 0.14801281533840815 2.002546843956193e-06 5.698417316025878 0.2749722938084962 TES(ph)LPSSQQYVPFGGK ddPTM_PC-9_AZD4547_30min_R2 1 TESLPSSQQYVPFGGK 16 0 Q13009-2;Q13009;H7C079;A0A1B0GW57 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 T(0.014)ES(0.977)LPS(0.007)S(0.002)QQYVPFGGK 127.05 0.0001495 0.0 10610.0 12641.0 15075.0 15769.0 16673.0 16430.0 11914.0 19548.0 13994.0 12948.0 True False 13983.759298290332 16726.956041771897 14875.09565016998 12133.700678621379 14358.24174692911 15402.629502696685 12974.322919523767 16527.305768352333 14733.694270682767 12494.694461064468 1.1191757703132346 1.3387246958215628 1.1905129570413455 0.9711082344936081 1.1491470873234846 1.2327335854985348 1.0383865695919097 1.3227458918546706 1.179196043296248 1.0 13.609028002470938 -5.524718414901541 24.996714737900884 1.1378687197784088 1.2378674018166558 0.1160834112489545 0.11224415327364595 117.77363464200164 1600254.3230435378 0.03018093509537627 0.05271918829101458 2.987318889989336e-06 5.524718414901541 0.09999868203824702 TES(ph)LPSSQQYVPFGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TESLPSSQQYVPFGGK 16 0 Q13009-2;Q13009;H7C079;A0A1B0GW57 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 T(0.023)ES(0.755)LPS(0.072)S(0.15)QQYVPFGGK 115.38 0.00017717 2613700.0 19423.0 25507.0 20121.0 20342.0 22347.0 14224.0 14676.0 14805.0 11671.0 10823.0 True False 22710.930278263568 28039.16639010963 20600.760949317435 19202.303689653814 17968.265769281756 13478.068400079077 13285.783034961272 14416.384437194158 11841.666295637251 12785.12422517914 1.7763558553100687 2.193108639092379 1.6113070617449388 1.5019254683373842 1.4054040815571343 1.0541992524042314 1.0391594794828924 1.1275904858869028 0.9262065887726117 1.0 13.642178557976427 -6.029178334406111 0.8325691826442649 1.003834014706521 2.0349374810780163 0.8805201281146726 0.1348024756231279 0.21631568457188188 0.3035565185340433 0.06385272354352148 0.1456761826158257 9.350216472317797e-07 6.029178334406111 1.0311034663714953 TES(ph)LPSSQQYVPFGGK ddPTM_PC-9_Lapatinib_30min_R1 1 TESLPSSQQYVPFGGK 16 0 Q13009-2;Q13009;H7C079;A0A1B0GW57 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 T(0.009)ES(0.986)LPS(0.004)SQQYVPFGGK 147.53 3.9372000000000006e-10 0.0 11584.0 21328.0 17654.0 23458.0 17374.0 17755.0 15576.0 19539.0 18061.0 27870.0 True False 11418.810035754574 21278.61632638841 16202.556266410704 25183.17957359401 16352.095478598236 16995.660038926515 16382.449066046676 20446.853270626387 16026.779989238463 32687.292365559304 0.34933483960837053 0.6509751890250918 0.4956836462686764 0.770427213485815 0.500258488703319 0.5199470133180517 0.5011870938355208 0.6255291212853729 0.49030613517946037 1.0 14.996442256729164 -10.840671444729715 4.957783930696709 1.0001857098842482 0.5522045290693931 0.6132477390130666 0.10829456518060047 0.0002102243097954747 2.892757696623255e-05 0.0991598717208719 0.02403994146887921 1.4432067627462894e-11 10.840671444729715 -0.44798118081485505 TES(ph)PATAAETASEELDNR ddPTM_PC-9_AZD4547_30min_R2 7 TESPATAAETASEELDNR 18 0 Q9NTJ3;C9JWF0;C9IYK2;C9JJ64;C9JR83;Q9NTJ3-2 Q9NTJ3 SMC4 Structural maintenance of chromosomes protein 4 1 TES(0.818)PAT(0.182)AAETASEELDNR;T(0.018)ES(0.979)PAT(0.003)AAETASEELDNR;T(0.001)ES(0.997)PAT(0.001)AAETASEELDNR;T(0.309)ES(0.691)PATAAETASEELDNR;T(0.01)ES(0.99)PATAAETASEELDNR;T(0.006)ES(0.992)PAT(0.001)AAETASEELDNR;T(0.318)ES(0.682)PATAAETASEELDNR 411.75 0.0 516502000.0 398197.0 374015.3 445055.0 471320.0 508069.0 516991.0 472467.5 508167.0 424084.0 418176.0 True False 524815.3629878708 494908.43145717296 439153.27990622935 362664.4558214107 437532.38925931347 484663.4710425244 514516.1922091741 429641.4666659649 446500.2144553547 403535.78552286763 1.3005423107838114 1.2264300942131126 1.0882635336472366 0.8987169634819392 1.0842468126894766 1.2010421093498271 1.2750199874900994 1.0646923571084823 1.1064699351925318 1.0 18.622337091699826 -5.110001595442347 3.441759510304353 1.0959473022117314 1.2884241391787248 0.35097754157771854 0.09640851594264478 0.306880449271722 6.526626663326522 0.027810286933727068 0.0964555415859825 7.762442649801014e-06 5.110001595442347 0.19247683696699336 TES(ph)PATAAETASEELDNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 TESPATAAETASEELDNR 18 0 Q9NTJ3;C9JWF0;C9IYK2;C9JJ64;C9JR83;Q9NTJ3-2 Q9NTJ3 SMC4 Structural maintenance of chromosomes protein 4 1 T(0.095)ES(0.679)PAT(0.155)AAET(0.053)AS(0.019)EELDNR;T(0.009)ES(0.991)PATAAETASEELDNR;TES(0.998)PAT(0.002)AAETASEELDNR;TES(0.985)PAT(0.015)AAETASEELDNR;T(0.004)ES(0.996)PATAAETASEELDNR;T(0.007)ES(0.99)PAT(0.003)AAETASEELDNR;T(0.086)ES(0.913)PATAAETASEELDNR;T(0.009)ES(0.99)PATAAETASEELDNR 319.11 9.948699999999998e-157 434526100.0 294196.9 341863.4 337768.9 326691.5 352562.2 302893.6 356350.5 287415.1 293648.9 260575.5 True False 343998.62451636046 375801.3390554984 345822.5915716858 308388.0344031329 283480.1677989294 287009.32640229125 322594.4008857976 279870.7581664712 297942.9596333603 307815.77543547767 1.1175470913720833 1.2208644554485202 1.123472606569428 1.0018590956452627 0.9209409991995379 0.9324061640318765 1.0480112672244042 0.9092151231382742 0.9679262188945646 1.0 18.23170764554193 -5.7508319456908845 2.9882452713647623 0.9612431957919373 1.1700489861295105 0.7884159535562554 0.044685641301384194 0.10208016975453803 1.8684869571081726 0.012571020264427265 0.022225985883419275 1.7748761529416305e-06 5.7508319456908845 0.20880579033757318 TES(ph)PATAAETASEELDNR ddPTM_PC-9_Lapatinib_30min_R1 9 TESPATAAETASEELDNR 18 0 Q9NTJ3;C9JWF0;C9IYK2;C9JJ64;C9JR83;Q9NTJ3-2 Q9NTJ3 SMC4 Structural maintenance of chromosomes protein 4 1 T(0.068)ES(0.931)PAT(0.001)AAETASEELDNR;T(0.013)ES(0.986)PAT(0.001)AAETASEELDNR;T(0.015)ES(0.917)PAT(0.067)AAETAS(0.001)EELDNR;T(0.001)ES(0.999)PATAAETASEELDNR;T(0.002)ES(0.996)PAT(0.001)AAETASEELDNR;T(0.061)ES(0.871)PAT(0.068)AAETASEELDNR;T(0.004)ES(0.996)PATAAETASEELDNR;T(0.033)ES(0.967)PATAAETASEELDNR;T(0.148)ES(0.681)PAT(0.169)AAET(0.001)AS(0.001)EELDNR 308.42 4.362899999999999e-138 414220200.0 444425.89999999997 550571.3 556867.2 451395.8 532444.2 548060.1000000001 545824.6 512934.5 558485.9 469253.60000000003 True False 438088.3051682723 549296.4859818502 511083.7283855541 484592.9529442465 501126.8789815738 524620.8471134929 574084.7270477213 536767.3094294533 495583.3368247512 550363.45951888 0.7959981673769602 0.9980613292569195 0.9286294712086015 0.8804962331036128 0.9105380640997712 0.9532261599854559 1.04310109459225 0.9752960523554521 0.9004655528148312 1.0 19.070025162280444 -6.879258940002706 4.0814462074200755 0.9799815735787967 0.9082618151634838 0.28682221232518035 0.05717639310596517 0.3205611365199682 9.719477704684072 0.020744729677226605 0.018245676336597186 1.320508071061984e-07 6.879258940002706 -0.07171975841531286 TES(ph)PQGLPTVQR ddPTM_PC-9_AZD4547_30min_R2 1 TESPQGLPTVQR 12 0 F5H212;P15822;A0A0D9SFF3;P15822-2;P15822-3 F5H212 HIVEP1 Zinc finger protein 40 1 T(0.033)ES(0.954)PQGLPT(0.013)VQR 120.9 0.00047175 9440800.0 15986.0 19490.0 26565.0 45766.0 29399.0 26825.0 19926.0 28457.0 27570.0 29227.0 True False 21069.215470543753 25789.76135227706 26212.730742737334 35215.355777651486 25317.45631367896 25147.62850942414 21699.37539822314 24059.624526805936 29027.293914729464 28203.771626006423 0.7470353876754567 0.9144082463246359 0.9294051551093554 1.2486044861170182 0.8976620804266469 0.8916406232078463 0.7693784961091642 0.8530640811394455 1.0291990128002484 1.0 14.783600483389568 -6.481108498063709 24.99986221684374 0.8911991354436003 0.9692774305709898 0.027008437875371105 0.1338625769456316 1538.1523216990454 920597.8064716342 0.04349426704486738 0.04931341887520396 3.3028701643671426e-07 6.481108498063709 0.07807829512738951 TES(ph)PQGLPTVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TESPQGLPTVQR 12 0 F5H212;P15822;A0A0D9SFF3;P15822-2;P15822-3 F5H212 HIVEP1 Zinc finger protein 40 1 TES(1)PQGLPTVQR 200.76 4.2898e-06 7018800.0 34911.0 28979.0 33989.0 35972.0 40531.0 31609.0 34587.0 32552.0 32059.0 20798.0 True False 40820.74277631982 31855.84360446099 34799.42666400031 33956.60546279752 32589.241504217985 29951.368395535697 31310.668971804665 31697.54449169497 32527.80222533071 24568.512763122595 1.6615064643876967 1.2966126159771747 1.4164238185485263 1.3821188848584467 1.3264637472535385 1.2190957053164726 1.2744226430670262 1.2901694456358412 1.3239630147314017 1.0 14.584522907407916 -1.5228787453139532 0.03452839603270658 8.905220556801254e-13 3.3407261031175786 0.6730827794010179 0.08966494201960569 642.5497610883386 1.7026082750099423 49.08927696479856 135.60693671422308 0.029999999997677915 1.5228787453139532 3.340726103116688 TES(ph)VPSDINNPVDR ddPTM_PC-9_AZD4547_30min_R2 2 TESVPSDINNPVDR 14 0 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;A8MY87 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 TES(0.999)VPSDINNPVDR;T(0.225)ES(0.775)VPSDINNPVDR 238.64 4.2183e-27 39995000.0 40452.0 43514.0 50502.0 67254.0 56040.0 59323.0 49921.0 68214.0 50717.0 51481.0 True False 53314.89454613009 57579.04953735168 49832.31048257936 51749.6293639421 48259.81332081256 55613.523432043505 54363.872290208616 57673.09370177956 53397.797079192416 49678.665859596884 1.0731949746156633 1.1590297070392965 1.003092768703103 1.0416871803723198 0.971439399302825 1.1194649145615114 1.0943102305495318 1.1609227563553484 1.0748637499667693 1.0 15.60033880947684 TES(ph)VPSDINNPVDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TESVPSDINNPVDR 14 0 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;A8MY87 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 T(0.156)ES(0.465)VPS(0.379)DINNPVDR 75.02 0.017973 18229000.0 16221.0 17333.0 17529.0 17943.0 21194.0 17414.0 19844.0 17806.0 16495.0 14139.0 True False 18966.89492064631 19053.705690193667 17946.957839102688 16937.711881990876 17041.187842402 16500.779184405033 17964.2326618814 17338.61136701648 16736.20816952587 16702.288775737594 1.1355865759067927 1.1407841132451162 1.0745208683718335 1.0140952602014202 1.0202905764123 0.9879352109140107 1.075555147147076 1.038097927764441 1.0020308230951886 1.0 14.027758193575307 -5.4728751734524925 2.6807328408503266 1.0223208324763873 1.1393292814580025 0.8051175810730961 0.02326570549111869 0.11932203199605405 1.67778176857002 0.006752919782577902 0.015998097322594766 3.3660830469318573e-06 5.4728751734524925 0.11700844898161522 TES(ph)VPSDINNPVDR ddPTM_PC-9_Lapatinib_30min_R1 2 TESVPSDINNPVDR 14 0 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;A8MY87 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 T(0.115)ES(0.884)VPSDINNPVDR;TES(0.998)VPS(0.002)DINNPVDR 247.9 3.5279000000000004e-35 43418000.0 71636.0 60415.0 66108.0 61831.0 63457.0 61216.0 56956.0 54045.0 52644.0 47959.0 True False 70614.45750356666 60275.11277938653 60672.855424259615 66378.25800216947 59724.58402126213 58597.93438146577 59904.90299215166 56556.128000972574 46714.678354103846 56248.64924864942 1.2553982797242405 1.0715832928349616 1.0786544429903164 1.1800862578715752 1.0617958798841054 1.0417660719714574 1.065001627458459 1.0054664201972912 0.8305031139076733 1.0 15.779530831511604 -7.322536694703651 0.7946127425876894 0.9276825286844294 1.1385727495799127 0.5668001714884052 0.06986543646107493 0.4979462817951012 0.6076271412249373 0.057525248994859786 0.03349398115803774 4.758425840761919e-08 7.322536694703651 0.21089022089548337 TESEVPPRPAS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 TESEVPPRPASPK 13 1 Q9Y3L3;A0A2R8Y5V0;Q6ZT62-2;Q6ZT62;A0A3B3IU28 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 TESEVPPRPAS(1)PK 95.755 0.016582 12611000.0 43890.0 34765.0 36951.0 53350.0 50188.0 49642.0 46033.0 45524.0 36973.0 49610.0 True False 57846.10703128769 46002.106383371545 36461.00559664552 41050.98174928347 43220.26250793967 46537.87789244482 50129.847822262695 38489.31183744994 38927.3172981245 47873.16900010877 1.2083199888262308 0.9609162573563289 0.7616167126216916 0.8574945550228814 0.9028076354803558 0.9721077351770693 1.047138697297202 0.8039850430073365 0.8131343320521784 1.0 15.546929689041805 -4.798332488635391 3.8172388986840153 0.8932013794005201 1.234017068925013 0.5395997026388917 0.08652852167703887 0.1898918224456009 4.918009989181734 0.023044334382533994 0.17579520672139246 1.590990225011475e-05 4.798332488635391 0.3408156895244928 TESEVPPRPAS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TESEVPPRPASPK 13 1 Q9Y3L3;A0A2R8Y5V0;Q6ZT62-2;Q6ZT62;A0A3B3IU28 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 TESEVPPRPAS(1)PK;TESEVPPRPAS(1)PK;TESEVPPRPAS(1)PK 118.52 0.0017084 32675600.0 113333.4 133254.2 106326.3 164053.9 155506.4 113871.3 151478.2 104931.6 107182.0 118192.4 True False 132518.50618331638 146482.79632967204 108861.5222367381 154862.4918529202 125036.03723203253 107899.68856903305 137129.08828880292 102177.2566842203 108749.33398157776 139619.7465094766 0.9491387106502287 1.049155294947693 0.7797000421380167 1.1091732775951504 0.8955469434514823 0.7728110905982015 0.982161132053734 0.7318252556581248 0.7788965150011676 1.0 17.09114347169104 -6.517026029355567 24.714005738086012 0.8433014547836957 0.9684423480181548 0.1945949686581656 0.1130028041748751 350.3016612715619 1479211.493084587 0.035167075704108416 0.036293217440431035 3.04070277628346e-07 6.517026029355567 0.1251408932344591 TESEVPPRPAS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 7 TESEVPPRPASPK 13 1 Q9Y3L3;A0A2R8Y5V0;Q6ZT62-2;Q6ZT62;A0A3B3IU28 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 T(0.001)ES(0.002)EVPPRPAS(0.998)PK;TES(0.001)EVPPRPAS(0.999)PK;T(0.01)ESEVPPRPAS(0.99)PK;TESEVPPRPAS(1)PK;TESEVPPRPAS(1)PK;TESEVPPRPAS(1)PK;TESEVPPRPAS(1)PK 115.91 0.0016414 93141000.0 396709.1 366138.30000000005 322703.8 310892.5 356326.7 309584.1 306408.4 322381.9 290033.0 249970.1 True False 391051.9554864608 365290.5292618194 296172.339236692 333756.5715569768 335368.2640712464 296343.90971878485 322272.72768418473 337360.93998698745 257366.42935711215 293177.0987207785 1.333842094736391 1.245972249727874 1.0102164886990923 1.138412833107562 1.143910167385382 1.0108016997638087 1.099242502536383 1.1507070008503277 0.8778531149945912 1.0 18.161412887416184 -1.5228787455251795 0.5535887671138031 1.045266940866518 14.875553026610385 0.5607794101678509 0.08312534104980324 104.84017443249103 0.9493374953328514 0.04033629720414409 1726.4668069731197 0.029999999983086913 1.5228787455251795 13.830286085743866 TESGYGSESS(ph)LRR ddPTM_PC-9_Lapatinib_30min_R1 1 TESGYGSESSLRR 13 1 A0A2U3TZL3;Q9Y5P4;Q9Y5P4-3;A0A2R8YCI0;A0A2R8YFI2;A0A2R8YEA4;A0A2R8Y5H3;A0A2R8Y7Q9;A0A2R8YEK8;A0A2R8YE18;A0A2R8Y5S9;A0A2R8Y7C5;Q9Y5P4-2 A0A2U3TZL3 COL4A3BP Collagen type IV alpha-3-binding protein 1 TESGYGS(0.003)ES(0.201)S(0.796)LRR 62.924 0.021778 3432400.0 20811.0 29091.0 17121.0 20769.0 23423.0 15151.0 15039.0 20353.0 17159.0 18352.0 True False 20514.231323729993 29023.641576845723 15713.377468971215 22296.421543352983 22045.30519138982 14503.027048706028 15817.645833607849 21298.674682279492 15226.372727719561 21524.118747497098 0.9530811256147461 1.3484241523347245 0.7300358102139919 1.03588080910145 1.0242140665551442 0.6738035233332139 0.7348800672941457 0.9895259793043178 0.7074098087983341 1.0 14.393666550753817 -5.6074377578265455 0.9044406216878966 0.8349814438842315 1.1404433577317807 0.19828606787877534 0.17825281619683087 1.2486921140939073 1.7126086004200027 0.07101962181948282 0.2959294689090818 2.4692339649766874e-06 5.6074377578265455 0.3054619138475493 TESIT(ph)ATSPASMVGGKPGSFR ddPTM_PC-9_Lapatinib_30min_R1 1 TESITATSPASMVGGKPGSFR 21 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 T(0.006)ES(0.097)IT(0.448)AT(0.365)S(0.083)PASMVGGKPGSFR 95.344 0.00025316 9461200.0 8548.2 8489.9 8478.4 8254.4 10588.0 9791.6 10458.0 7967.9 8997.1 10047.0 True False 8426.301100452107 8470.242158167905 7781.338679570437 8861.456111871197 9965.234656808925 9372.83609333443 10999.464068613002 8338.117722249046 7983.751854336822 11783.610563214013 0.7150865225262341 0.7188155203134634 0.6603526684649748 0.7520153576302686 0.8456860147702369 0.7954129206030008 0.9334544798137717 0.7076029606985587 0.6775301858040386 1.0 13.524494036165866 -6.025243430203028 4.809304390016126 0.8151110388693789 0.7002754713919578 0.2868316988600449 0.09067756628583455 0.28076215384927933 16.87493393482734 0.02679934218360981 0.03704125073145192 9.4353186073274e-07 6.025243430203028 -0.11483556747742107 TESITAT(ph)SPASMVGGKPGSFR ddPTM_PC-9_AZD4547_30min_R2 1 TESITATSPASMVGGKPGSFR 21 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 T(0.001)ES(0.002)IT(0.094)AT(0.324)S(0.324)PAS(0.256)MVGGKPGSFR 71.637 0.0016985 9208600.0 24627.0 17771.0 24917.0 35623.0 34432.0 33099.0 28873.0 31602.0 27572.0 27774.0 True False 32457.87372657832 23515.1282191542 24586.58429952143 27410.66771986364 29651.711139582738 31029.314297611527 31442.641065587537 26718.63704171632 29029.399630646392 26801.640713747674 1.2110405505857456 0.8773764438642114 0.9173537009213749 1.022723497140366 1.1063394012431913 1.1577393574153578 1.1731610538850072 0.9969030376566171 1.0831202440437167 1.0 14.710033700274813 -6.112987927107387 4.4281861165902825 1.0935043886558449 0.986875001893695 0.1283728304542473 0.09801986832993284 0.3866600048155468 12.34870479812715 0.02951456654265062 0.039080752514813244 7.709248996018849e-07 6.112987927107387 -0.10662938676214984 TESITAT(ph)SPASMVGGKPGSFR ddPTM_PC-9_Lapatinib_30min_R1 1 TESITATSPASMVGGKPGSFR 21 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 T(0.007)ES(0.022)IT(0.128)AT(0.759)S(0.083)PASMVGGKPGSFR 135.64 4.9735e-05 8623500.0 17933.0 16906.0 22815.0 19294.0 18729.0 22062.0 14478.0 19619.0 19766.0 17064.0 True False 17677.272131490572 16866.85519570155 20939.23876844683 20712.945122897218 17627.397042630735 21118.459689033876 15227.599998601927 20530.570362680748 17539.744934792514 20013.48966364924 0.883267857259198 0.8427743226778205 1.046256256173007 1.0349492003145462 0.8807757836779262 1.0552112622013945 0.7608668080639636 1.025836608593587 0.8763961322872231 1.0 14.288685125078565 -9.650820473385227 0.00499631934658027 1.9128943385070978 1.6915479694233086e-07 0.019646245932175566 0.09744406305175617 104828.27354838054 147.34837851720633 28761.292478429707 27652.112719971214 2.2344957172955397e-10 9.650820473385227 -1.912894169352301 TESLPS(ph)SQQYVPFGGK ddPTM_PC-9_AZD4547_30min_R2 1 TESLPSSQQYVPFGGK 16 0 Q13009-2;Q13009;H7C079;A0A1B0GW57 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 T(0.013)ES(0.349)LPS(0.602)S(0.035)QQY(0.001)VPFGGK 122.96 0.00060495 0.0 16141.0 18301.0 14188.0 19010.0 25782.0 22368.0 16954.0 23415.0 18367.0 15451.0 True False 21273.502246343465 24216.440354439324 13999.857849725478 14627.53820157222 22202.61432971428 20969.32542399995 18462.873155750036 19796.749773172192 19337.842123026327 14910.065192918371 1.426788010051589 1.624167301826492 0.9389534967543132 0.9810512571413612 1.4891024313065748 1.4063872392697159 1.2382825237088226 1.327744011647567 1.2969656317942162 1.0 13.86399894523884 -8.647549037862749 15.932376318174985 0.99999999954822 1.3000025112090148 0.16958815468625732 0.20122104912765154 13131.91562994424 1678218.7595755518 0.20678861538138874 0.05339259095265601 2.2513911891409983e-09 8.647549037862749 0.3000025116607947 TESSPSEASQHSMQS(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 2 TESSPSEASQHSMQSPQK 18 0 Q9UQR0 Q9UQR0 SCML2 Sex comb on midleg-like protein 2 1 TESSPSEASQHS(0.136)MQS(0.864)PQK;TESSPSEASQHS(0.018)MQS(0.982)PQK 101.48 0.00036286 23218900.0 4011.8 3871.8 20583.3 40170.0 29857.0 29710.0 13475.0 27315.0 22237.9 32036.0 True False 5287.46894937617 5123.283632824334 20310.351993110708 30909.427120313325 25711.870919334422 27852.229003354736 14674.248895466077 23094.094386256602 23413.34999442735 30914.42939099948 0.1710356313714003 0.16572467076865866 0.6569861515549733 0.9998381897778902 0.8317109979335492 0.9009459191720911 0.4746731278740141 0.747032852981601 0.757359927246271 1.0 14.915992756573536 -5.327189606925527 3.7434977386133856 0.7969682972329142 0.15824402202680035 0.7586655642256255 0.14342072978150716 0.10822432886039825 2.9830370674893785 0.03986633547241192 0.0956882770420945 4.707717491314873e-06 5.327189606925527 -0.6387242752061139 down TESSPSEASQHSMQS(ph)PQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TESSPSEASQHSMQSPQK 18 0 Q9UQR0 Q9UQR0 SCML2 Sex comb on midleg-like protein 2 1 TESSPSEASQHS(0.035)MQS(0.965)PQK;TESSPSEASQHS(0.206)MQS(0.794)PQK 73.464 0.0048684 8065900.0 4594.2 5079.200000000001 17331.6 20943.9 27252.8 27047.8 22169.3 20956.5 24423.9 14409.4 True False 5371.907320413868 5583.429408736614 17744.851074459013 19770.48118403994 21912.809475861734 25629.365753069396 20069.263412167275 20406.414080247167 24781.05333202078 17021.710155252367 0.3155915164467928 0.3280181226099507 1.0424834468811295 1.161486184626366 1.2873447659488038 1.5056868857070143 1.179039193425258 1.1988462906560764 1.4558498004017606 1.0 14.05508837007258 -5.346721129460782 2.2323434774211695 1.2749552380438285 0.2635654639365092 0.8738625298876139 0.13951156954512645 0.09915000475148131 0.9314757494215691 0.0385507829213684 0.1202309176646051 4.500687616958802e-06 5.346721129460782 -1.0113897741073192 down TESSPSEASQHSMQS(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 1 TESSPSEASQHSMQSPQK 18 0 Q9UQR0 Q9UQR0 SCML2 Sex comb on midleg-like protein 2 1 TESSPSEASQHS(0.222)MQS(0.778)PQK 69.069 0.007879 2937700.0 12522.0 7991.0 27421.0 13544.0 20234.0 24818.0 15645.0 15378.0 29129.0 16914.0 True False 12343.433983746447 7972.497330465578 25166.551228120992 14540.070941459519 19043.87590157457 23756.591993583676 16455.021548427074 16092.518020149071 25848.185278031513 19837.562363511657 0.6222253398658707 0.40188896117245937 1.2686312343703703 0.7329565334198463 0.9599907263103576 1.197556008054725 0.8294880815948293 0.8112144892231792 1.3029920110333482 1.0 14.27594713802957 -5.249112726509184 24.98945064113963 0.9942747562491446 0.5120571046117445 0.521035193938546 0.1913991497691412 589.6207845888192 1195315.2813339878 0.04696931150454674 0.1223634870609042 5.6349137567999095e-06 5.249112726509184 -0.48221765163740016 TESSS(ph)VVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TESSSVVR 8 0 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 T(0.015)ES(0.036)S(0.036)S(0.914)VVR 97.965 0.0056512 3163300.0 21302.0 23009.0 28355.0 19767.0 28532.0 26506.0 22291.0 18079.0 20706.0 15727.0 True False 24908.00786632191 25293.181458816493 29031.090736936334 18659.519075478674 22941.35941867576 25115.97869885377 20179.43510713556 17604.445406283903 21008.786078096553 18578.18060513649 1.3407129791512173 1.3614455579048166 1.5626444458673108 1.0043781720110792 1.2348550111700893 1.3519073386502503 1.0861900600512169 0.9475871604680509 1.1308311898038093 1.0 14.181321602450312 -6.676070503437284 0.46796698845099416 0.9902219295434469 1.4305553766457801 0.4655782095985077 0.13896357163318324 1.1072979979878759 0.5054531637924211 0.13410631276161314 0.20681056988155294 2.1082858626784934e-07 6.676070503437284 0.44033344710233324 TET(ph)DSVGTPQSNGGMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TETDSVGTPQSNGGMR 16 0 Q9H0H5;F8VRD2;H0YIK5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 T(0.007)ET(0.67)DS(0.282)VGT(0.034)PQS(0.007)NGGMR 85.469 0.018035 3567600.0 22218.0 20263.0 18217.0 19241.0 24149.0 20105.0 22871.0 14232.0 13794.0 14404.0 True False 25979.06857449725 22274.576726498264 18651.362368357226 18162.98915016366 19417.17680504699 19050.658407170267 20704.49330829921 13858.425080050465 13995.711154315843 17015.331177998727 1.5268035810016365 1.3090886385626088 1.0961504171293432 1.067448465161165 1.1411577360394791 1.1196172562191016 1.2168140068334765 0.8144669612995705 0.8225353363919632 1.0 14.054547611029077 -1.5228787452803376 0.3618997649330132 0.9561423780332303 7.910690131567042 0.6818127268509322 0.1142026850876164 42.358679598891186 0.5901720354354459 0.10346341751715615 203.28054838572763 0.029999999999999995 1.5228787452803376 6.954547753533812 TET(ph)PIVSK ddPTM_PC-9_AZD4547_30min_R2 1 TETPIVSK 8 0 O95292 O95292 VAPB Vesicle-associated membrane protein-associated protein B/C 1 T(0.003)ET(0.982)PIVS(0.014)K 114.51 0.0089837 16789000.0 74978.0 86414.0 102820.0 78421.0 105840.0 95751.0 118990.0 117120.0 107710.0 87092.0 True False 98819.44436071732 114345.63558212775 101456.53961860546 60342.25004237223 91145.94293138462 89763.6748333967 129579.87948582626 99021.79514985815 113403.33070567687 84042.93558874165 1.1758209499520995 1.3605621314999072 1.2071989026546632 0.7179931260094591 1.0845164116755874 1.0680692458513004 1.5418295253263943 1.1782286572474638 1.3493499472770478 1.0 16.358838935246183 TET(ph)PIVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TETPIVSK 8 0 O95292 O95292 VAPB Vesicle-associated membrane protein-associated protein B/C 1 T(0.006)ET(0.984)PIVS(0.01)K;T(0.029)ET(0.898)PIVS(0.073)K 94.40899999999999 0.016485 17847100.0 225810.0 269230.0 208950.0 174427.0 311080.0 157591.0 230350.0 119401.0 124476.0 130905.0 True False 264035.1730492043 295957.3751209167 213932.1604472874 164654.42068996423 250126.1071064647 149326.65053689975 208529.58041041996 116266.85026581676 126296.22601454366 154637.04025659052 1.7074510260354734 1.913884116184791 1.3834470712340847 1.0647799545099401 1.6175044911065835 0.9656590056891984 1.3485099046412496 0.7518693456166401 0.8167268709034995 1.0 17.238526404268782 -5.1816174018463235 0.3658934077276578 0.8582839017084335 2.376435568912194 0.6236282991425119 0.2316369851858222 3.037240839011511 0.40441461520746613 0.22103981250483387 1.9847372441530824 6.5823746604278514e-06 5.1816174018463235 1.5181516672037607 TET(ph)PIVSK ddPTM_PC-9_Lapatinib_30min_R1 1 TETPIVSK 8 0 O95292 O95292 VAPB Vesicle-associated membrane protein-associated protein B/C 1 T(0.281)ET(0.717)PIVS(0.002)K 93.096 0.018293 17025000.0 193840.0 262490.0 102710.0 82429.0 108370.0 131070.0 130420.0 94518.0 145570.0 37617.0 True False 191075.80605409763 261882.22053233706 94265.58027206545 88491.10363508316 101995.88966361767 125464.44163909322 137172.509450039 98909.65133492311 129174.37367994252 44119.048328498175 4.330914044913214 5.935808464915988 2.136618622645487 2.0057346426922673 2.3118334036623955 2.843770352998547 3.1091447945270856 2.2418808900516014 2.927859475076299 1.0 15.42911405110966 -5.268366444449899 24.998725460893272 2.401531738232575 5.133361305703149 0.7373705740353163 0.6697623719615939 227.42104896333657 820730.2964945304 0.1670367796103794 0.3601289535495421 5.390555918894371e-06 5.268366444449899 2.731829567470574 TET(ph)PPPLASLNVSK ddPTM_PC-9_AZD4547_30min_R2 3 TETPPPLASLNVSK 14 0 K7ELG9;Q3MHD2;Q3MHD2-2 K7ELG9 LSM12 Protein LSM12 homolog 1 T(0.038)ET(0.962)PPPLASLNVSK;T(0.12)ET(0.88)PPPLASLNVSK;T(0.001)ET(0.999)PPPLASLNVSK 155.06 0.00076934 89526000.0 91142.0 108149.0 95480.0 80022.0 93678.0 127526.0 119160.0 117839.0 120566.0 83891.0 True False 120123.26012863126 143106.0492810369 94213.87281447636 61574.164227575595 80672.4266999834 119551.77906030996 129765.00915649258 99629.69022083424 126938.87261963272 80954.00162443303 1.4838458596020336 1.767745218388877 1.1637951296287905 0.7606068012948191 0.9965217911554771 1.476786528909864 1.602947433760059 1.2306950641308956 1.568037034272075 1.0 16.30481477546997 TET(ph)PPPLASLNVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TETPPPLASLNVSK 14 0 K7ELG9;Q3MHD2;Q3MHD2-2 K7ELG9 LSM12 Protein LSM12 homolog 1 T(0.031)ET(0.963)PPPLAS(0.001)LNVS(0.006)K;T(0.04)ET(0.959)PPPLASLNVSK;T(0.235)ET(0.764)PPPLAS(0.001)LNVSK;T(0.006)ET(0.994)PPPLASLNVSK 149.35 4.7374e-05 83463000.0 76275.0 128794.0 91965.0 86340.0 93857.0 57341.3 91019.0 64430.0 59297.8 62404.0 True False 89186.85100007994 141579.81715010674 94157.79437920483 81502.64971805684 75466.39460811201 54334.221284410516 82397.02139950519 62738.78076922789 60164.91814458389 73717.3512102079 1.2098488284767608 1.9205765647545634 1.2772813026163978 1.1056101227192614 1.0237263462290804 0.7370614976313293 1.1177425673441097 0.8510720982137002 0.816156809175377 1.0 16.16971661296312 -5.7362848036757965 2.0311204356670842 0.9227038550272467 1.5702079074820479 0.6189533091523068 0.19587770293787182 0.1896528938003247 1.5938979263480593 0.0563404532803025 0.11337555831862614 1.8353343644235285e-06 5.7362848036757965 0.6475040524548011 TET(ph)PPPLASLNVSK ddPTM_PC-9_Lapatinib_30min_R1 3 TETPPPLASLNVSK 14 0 K7ELG9;Q3MHD2;Q3MHD2-2 K7ELG9 LSM12 Protein LSM12 homolog 1 T(0.031)ET(0.969)PPPLASLNVSK;T(0.015)ET(0.971)PPPLAS(0.002)LNVS(0.012)K;T(0.383)ET(0.615)PPPLAS(0.001)LNVS(0.001)K 149.35 0.0005457000000000001 64386000.0 53190.0 65003.0 52468.0 51566.0 74995.0 63649.0 66909.0 59851.0 59462.0 51788.0 True False 52431.50084614863 64852.489547272424 48154.28357233696 55358.33565913331 70583.94154584287 60926.880643065786 70373.22063174857 62631.89595681764 52764.76339738096 60739.4867968276 0.8632193587925919 1.067715467603517 0.7928003035885387 0.911406048660007 1.1620766863234255 1.0030852062821178 1.158607428922566 1.0311561598523233 0.8687061116251782 1.0 15.890347098413734 -6.205155447890688 22.865021471130085 1.0431871839518818 0.9118524381106691 0.2778189466353813 0.10116833140529054 154.98409303317936 62960.56296863857 0.02969762758227549 0.038339427659898576 6.235116207781088e-07 6.205155447890688 -0.13133474584121274 TET(ph)QEKNPLPSK ddPTM_PC-9_Lapatinib_30min_R1 2 TETQEKNPLPSK 12 1 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 1 T(0.154)ET(0.846)QEKNPLPSK;T(0.102)ET(0.898)QEKNPLPSK 80.719 0.010083 114396000.0 241500.0 419390.0 367820.0 515330.0 470160.0 457000.0 478010.0 514060.0 408770.0 1033080.0 True False 238056.16571432378 418418.9282222449 337579.2594262597 553229.0872904866 442506.11317012535 437455.1753190317 502759.0188791073 537945.104268295 362730.0180610711 1211646.50150743 0.19647328277525997 0.34533085986852 0.27861200358872956 0.4565928153155271 0.3652105730669762 0.361041916742867 0.4149386956126364 0.44397858913390026 0.2993695088541027 1.0 20.20853742249976 -14.522878745280282 0.2827496876890343 5.7635082466228855 0.3182075085371575 0.875380063484714 0.07360619836183857 74.58008497864088 0.7105769389610583 208.83310381817216 0.08169537987448308 3.0000000000003816e-15 14.522878745280282 -5.445300738085728 TET(ph)QEKNPLPSKETIEQEK ddPTM_PC-9_AZD4547_30min_R2 1 TETQEKNPLPSKETIEQEK 19 2 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 1 T(0.192)ET(0.808)QEKNPLPSKETIEQEK 74.14699999999999 0.036844 3077000.0 5850.0 3623.6 6058.8 9309.4 10076.0 8675.3 8127.0 7416.3 7304.0 8463.0 True False 7710.178312440949 4794.857836639874 5978.45635325041 7163.261658796239 8677.12132442019 8132.832119582747 8850.287255914855 6270.281244619982 7690.074528588465 8166.712945936718 0.9440981167676631 0.5871221222518317 0.7320517315629347 0.8771291101103611 1.0624986309500961 0.9958513508949977 1.0837025024025417 0.7677851892345144 0.9416364428989266 1.0 12.995539803568493 -5.921881812240749 3.8430224651889486 0.9704230371375253 0.738816448491875 0.42523217761798293 0.11425328748749483 0.20941061952299117 6.0724556276509984 0.03356022693014561 0.051237945238455165 1.1970662534497212e-06 5.921881812240749 -0.2316065886456503 TETDS(ph)VGTPQSNGGMR ddPTM_PC-9_AZD4547_30min_R2 1 TETDSVGTPQSNGGMR 16 0 Q9H0H5;F8VRD2;H0YIK5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 TET(0.004)DS(0.681)VGT(0.231)PQS(0.084)NGGMR 84.046 0.004462300000000001 3686100.0 12663.0 11290.0 15423.0 17325.0 14640.0 14268.0 10772.0 22610.0 12782.0 15404.0 True False 16689.57059323756 14939.271712016822 15218.480942790824 13330.98891858173 12607.488704794709 13375.819704472084 11730.687131870915 19116.144026112455 13457.63042502981 14864.710648612685 1.1227645789926755 1.0050159781220562 1.0237993394248246 0.8968212859108632 0.8481489483935134 0.8998372064322988 0.7891635033585893 1.2860084853314353 0.9053408938226325 1.0 13.85960376005875 -10.81801064977498 14.798826752101915 0.9999999907900101 0.9729263106885603 0.0026685641746919675 0.1375244365797294 0.0 0.0 0.13493424197413684 0.03272636095983147 1.520510243303205e-11 10.81801064977498 -0.027073680101449837 TETDS(ph)VGTPQSNGGMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TETDSVGTPQSNGGMR 16 0 Q9H0H5;F8VRD2;H0YIK5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 T(0.001)ET(0.019)DS(0.682)VGT(0.187)PQS(0.111)NGGMR 91.616 0.0028398000000000004 3934500.0 16839.0 15938.0 16498.0 17628.0 19868.0 13990.0 14634.0 12043.0 11899.0 9782.9 True False 19689.510114589935 17520.2193094275 16891.374889013427 16640.360310747106 15975.008023631353 13256.339772012541 13247.761579014943 11726.884010613241 12073.000364303629 11556.462328606209 1.7037662179585567 1.5160538589788801 1.461638900271537 1.4399181892850121 1.3823441438551423 1.147093236240519 1.1463509508634133 1.0147468729755802 1.0446968995363581 1.0 13.49641220627362 -6.4274695373023345 0.5354569190581139 0.974986445012483 1.6800669054807458 0.9506650088310592 0.05179004317437908 0.21886915276171298 0.13090295552858994 0.042969733488645745 0.07559612636400982 3.7370633732906905e-07 6.4274695373023345 0.7050804604682628 TETDS(ph)VGTPQSNGGMR ddPTM_PC-9_Lapatinib_30min_R1 1 TETDSVGTPQSNGGMR 16 0 Q9H0H5;F8VRD2;H0YIK5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 TET(0.002)DS(0.823)VGT(0.109)PQS(0.066)NGGMR 62.69 0.032081 3742000.0 18812.0 13050.0 14893.0 12694.0 13959.0 11418.0 9816.9 8020.4 12492.0 6950.6 True False 18543.737430301713 13019.783526789603 13668.555028642502 13627.559105942642 13137.959064449922 10929.678756658004 10325.171047539397 8393.057063909715 11085.019413408276 8152.001948907668 2.2747464422265615 1.5971271361796222 1.6767114525130884 1.671682513246783 1.6116236412591083 1.3407355426506655 1.2665810327637281 1.029570051198816 1.3597910651743184 1.0 12.992938681072474 -1.5228787452804127 0.1953369104361168 0.9526032972877395 6.276246838905432 0.8116509080542093 0.1534823755054978 22.7280732007971 0.2705007162616755 0.2990598188275231 36.768938927297796 0.029999999999994812 1.5228787452804127 5.323643541617693 up TETQEKNPLPSK ddPTM_PC-9_AZD4547_30min_R2 2 TETQEKNPLPSK 12 1 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 0 ; 85.67200000000001 0.012364 27852000.0 128831.0 113836.0 158243.0 160155.0 156648.0 140884.0 142559.0 159282.0 145458.0 157741.0 False True 169796.57814873144 150631.2608156908 156144.5944258605 123233.73912008424 134900.12914130324 132074.50120863755 155246.474826623 134668.62683623345 153146.61292160748 152218.5356026236 1.1154789886561283 0.9895723948423963 1.0257922519599463 0.809584316602506 0.886226691166369 0.867663722330286 1.0198920533035742 0.8847058362707856 1.0060970059612628 1.0 17.21578452049104 -4.891749228927933 1.449275687446329 0.9241599342601136 1.1558592490523032 0.3764091196422189 0.07016539485069488 0.984207620432788 2.2316394108268556 0.02035119360877946 0.31346536767428324 1.2830712420182603e-05 4.891749228927933 0.23169931479218964 TETQEKNPLPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TETQEKNPLPSK 12 1 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 0 ; 105.66 0.0022871 32470000.0 135729.0 138606.0 142370.0 163571.0 173826.0 140917.0 162475.0 129968.0 129303.0 140164.0 False True 158705.23893005424 152365.88766485805 145764.64074123203 154406.64717433683 139766.04312038157 133527.0644497993 147084.19178286512 126556.47771247901 131193.81175775733 165574.62366238632 0.9585118505457754 0.920224876823749 0.880356165196258 0.9325501925293729 0.8441271979296203 0.8064464318038653 0.8883256898277844 0.7643470654689999 0.7923545822170617 1.0 17.33712205354351 -6.294893107169576 7.02906709167364 0.8370545629873437 0.919694834250813 0.2291158741210294 0.06376913522619676 0.2865480948722719 48.2098055690822 0.018980540149288513 0.02186110510162507 5.071155091735218e-07 6.294893107169576 0.08264027126346929 TETQEKNPLPSK ddPTM_PC-9_Lapatinib_30min_R1 2 TETQEKNPLPSK 12 1 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 0 ; 84.352 0.013294 68393000.0 190615.0 237050.0 246590.0 228130.0 232640.0 191861.0 234110.0 202640.0 209910.0 207030.0 False True 187896.79514549044 236501.12528930808 226316.32206492723 244907.44121937046 218956.572587838 183655.5522798355 246231.0702909725 212055.3941736898 186267.72534970616 242814.85964986507 0.7738274149137102 0.9739977430966898 0.932053015170783 1.0086180128041704 0.9017428871674891 0.7563604325726346 1.014069199249311 0.8733213217653569 0.7671183123565876 1.0 17.8894971879875 -6.520803610313376 24.995601222438392 0.8765612121620181 0.9301187679352407 0.032591441112448716 0.09648848518093882 257.1011355656382 3096913.259657734 0.030995269853157106 0.0314670140861432 3.014368825565212e-07 6.520803610313376 0.05355755577322263 TETQEKNPLPSKETIEQEK ddPTM_PC-9_Lapatinib_30min_R1 1 TETQEKNPLPSKETIEQEK 19 2 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 0 69.935 0.029907 10480000.0 61684.0 43522.0 49381.0 48011.0 49039.0 44629.0 40948.0 33602.0 54069.0 29296.0 False True 60804.37484853977 43421.2274829837 45321.084796172356 51541.88910000097 46154.622434383484 42720.32170528026 43068.0870798972 35163.27159013193 47979.179848188636 34359.77456553374 1.769638352328789 1.2637227115727205 1.319015778457228 1.500064821487583 1.3432748910023742 1.243323690142396 1.2534449839813198 1.0233848165407982 1.3963764446905453 1.0 15.06843295053533 -1.5228787452803378 0.14461938495370258 0.9805551792092039 3.0649775032514714 0.5163112463654134 0.14655615595571833 62.0144318793324 0.5952133122679728 0.5671424151462499 26.889624990306405 0.02999999999999998 1.5228787452803378 2.0844223240422677 TEVCS(ph)PLRDQEYGQPCSR ddPTM_PC-9_AZD4547_30min_R2 1 TEVCSPLRDQEYGQPCSR 18 1 E9PJ09;A0A087WWZ6;Q9NQV5-2;Q9NQV5 E9PJ09 PRDM11 PR domain-containing protein 11 1 T(0.004)EVCS(0.994)PLRDQEY(0.002)GQPCSR 60.949 0.011695 5602800.0 3632.9 3922.3 13378.0 14788.0 8915.0 7773.9 3220.2 10270.0 6657.8 8186.1 True False 4788.086630985764 5190.106770243015 13200.598978970076 11378.855072322473 7677.306134101427 7287.796804078743 3506.7915616459995 8683.00748112228 7009.717715831915 7899.507130654915 0.6061247305423729 0.6570165308291487 1.6710661514240155 1.4404512691893854 0.9718715366821795 0.9225634819415046 0.44392536187954124 1.0991834474617923 0.8873614011474116 1.0 12.947546927528805 -6.624880139143398 3.8115219807201375 0.8504650911021793 1.1127341114657698 0.08290181950118347 0.3381215302082028 0.5846245550847039 16.146458081175084 0.12647369460304528 0.12642438738845146 2.372028270990263e-07 6.624880139143398 0.26226902036359057 TEVQAHS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 1 TEVQAHSPSR 10 0 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 TEVQAHS(0.974)PS(0.026)R 78.40100000000001 0.018954 0.0 6201.2 5047.7 5509.5 10397.0 8428.4 7387.8 7280.4 9103.5 7483.4 7618.1 True False 8173.052607027145 6679.270311846531 5436.44043015665 8000.132282048734 7258.262144774026 6925.839698114578 7928.341495996376 7696.7632526189645 7878.957246336103 7351.392637769178 1.1117692945737292 0.9085721088451335 0.7395116405871051 1.0882471765889 0.9873315849684485 0.9421126090493057 1.0784815730373336 1.0469802977296274 1.0717639003331778 1.0 12.843801862677193 -6.872069146582992 1.0708892574395812 1.0521748003666387 0.9432265129695578 0.11948238652098808 0.09995066527844737 1.0003655783835206 2.4167467317381677 0.059700093154213665 0.04843207879295057 1.3425511886363075e-07 6.872069146582992 -0.10894828739708085 TEVS(ph)PVPR ddPTM_PC-9_AZD4547_30min_R2 1 TEVSPVPR 8 0 E9PPY3;O43159 E9PPY3 RRP8 Ribosomal RNA-processing protein 8 1 T(0.017)EVS(0.983)PVPR 74.165 0.028172000000000003 38657000.0 245880.0 253930.0 259170.0 356100.0 312170.0 319350.0 223390.0 348750.0 280710.0 318540.0 True False 324064.7253782872 336007.9066282052 255733.23646133032 274006.6466901562 268830.5839464321 299380.99401620065 243271.27723622718 294858.7009777401 295547.75751917704 307388.01155603083 1.0542529740761102 1.0931067380516808 0.831955791531301 0.8914031659956593 0.8745643090814865 0.9739514319400493 0.7914143300669473 0.9592394299476221 0.961481080615613 1.0 18.22970137399402 -5.2499685419767195 24.993989552833263 0.9050929027787628 1.0736798804527818 0.5143442004199235 0.0632506133729184 543.173616742934 1183524.1379732995 0.015569211232532463 0.04044442180954536 5.623820597332525e-06 5.2499685419767195 0.1685869776740191 TEVS(ph)PVPR ddPTM_PC-9_Lapatinib_30min_R1 2 TEVSPVPR 8 0 E9PPY3;O43159 E9PPY3 RRP8 Ribosomal RNA-processing protein 8 1 T(0.016)EVS(0.984)PVPR;TEVS(1)PVPR 91.265 0.0088545 89722000.0 348640.0 425870.0 446430.0 429130.0 510310.0 452340.0 394210.0 489360.0 501310.0 340290.0 True False 343668.3296672547 424883.92418037436 409726.248669635 460689.6517357159 480294.5691080621 432994.4726560417 414620.2649156561 512097.45209651004 444847.1887716701 399108.67309207714 0.8610896050058227 1.0645820369890853 1.0266032193570203 1.1542962676469615 1.203418019926755 1.0849036912714418 1.0388655844118937 1.2831027903479453 1.11460165805277 1.0 18.606422105054904 -3.973033694387006 0.9440532992965404 1.1321139970688756 2.9685184422514695e-13 0.4702147762872194 0.08047015241828974 6.812891415737895 1.5804334776538311 0.02618133251746482 11.369705262896025 0.00010640604607493763 3.973033694387006 -1.1321139970685787 TEVSETARPS(ph)SPDTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEVSETARPSSPDTR 15 1 O75132 O75132 ZBED4 Zinc finger BED domain-containing protein 4 1 TEVS(0.003)ET(0.005)ARPS(0.604)S(0.364)PDT(0.024)R 87.669 0.024567 3525800.0 11923.0 11153.0 12298.0 11209.0 15860.0 13606.0 12349.0 12849.0 11766.0 10665.0 True False 13941.328410015782 12260.196132390814 12591.230960424717 10580.996070068308 12752.346851962626 12892.477408005901 11179.213320982326 12511.727364640838 11938.055490914914 12598.480075906453 1.106588122219395 0.9731488289478206 0.9994246039650767 0.8398629045978002 1.0122131221487924 1.0233359365834689 0.8873461920507096 0.9931140335387344 0.9475790269133698 1.0 13.620962072066732 -4.6070456137069025 2.2417304020262256 0.9597663231029714 1.202852538376625 0.37037595100610843 0.05564640335943194 1.3635040658422304 5.074239557911543 0.014355125782024655 0.7884369701817665 2.471464554842058e-05 4.6070456137069025 0.2430862152736537 TEVSETARPS(ph)SPDTR ddPTM_PC-9_Lapatinib_30min_R1 1 TEVSETARPSSPDTR 15 1 O75132 O75132 ZBED4 Zinc finger BED domain-containing protein 4 1 TEVSET(0.017)ARPS(0.967)S(0.017)PDTR 185.27 2.1106e-06 9117900.0 8195.2 11358.0 9488.7 9704.9 10687.0 8709.9 8125.3 8693.0 9843.8 7669.5 True False 8078.334945184383 11331.701248833442 8708.575713441227 10418.630720597348 10058.411671450402 8337.397880768569 8545.988276601767 9096.908515356736 8735.087584190553 8995.162856033628 0.8980754517152215 1.2597549850064746 0.9681398605918325 1.1582481481820988 1.1182022863214294 0.9268757013305373 0.9500648752423008 1.0113111525551601 0.9710872080911102 1.0 13.134933686146093 -6.7570757234271275 24.999656881235214 0.9712120489731741 1.0885225190531982 0.24338887251237595 0.0952233229156505 146.2904994405787 838106.9621690594 0.0298402709164822 0.028855174673876976 1.7495416125928533e-07 6.7570757234271275 0.11731047008002404 TEVSETARPSS(ph)PDTR ddPTM_PC-9_Lapatinib_30min_R1 1 TEVSETARPSSPDTR 15 1 O75132 O75132 ZBED4 Zinc finger BED domain-containing protein 4 1 TEVS(0.001)ET(0.038)ARPS(0.202)S(0.678)PDT(0.081)R 171.15 0.00063951 11103000.0 9328.0 9200.1 10217.0 10300.0 10544.0 9386.5 8385.6 8426.3 8789.2 8014.7 True False 9194.981009454306 9178.797733702464 9376.997698760522 11057.496359792756 9923.822650301589 8985.06127600021 8819.765336944085 8817.81665972051 7799.267741620884 9400.030216083544 0.9781863247334678 0.9764647051875909 0.9975497400759827 1.1763256187063391 1.0557224202664617 0.9558545099809022 0.9382698921385785 0.9380625867173427 0.829706667142012 1.0 13.198449678954896 -6.901735195248849 3.9117971278941037 0.9239522130644602 1.0387730095928778 0.38892143789375977 0.06608140112613638 0.2536465840105787 7.32750502290979 0.026090992298497415 0.02274951046521063 1.2539054925599998e-07 6.901735195248849 0.11482079652841759 TEVSETARPSSPDT(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEVSETARPSSPDTR 15 1 O75132 O75132 ZBED4 Zinc finger BED domain-containing protein 4 1 TEVS(0.001)ET(0.006)ARPS(0.043)S(0.321)PDT(0.629)R 125.67 0.00026538 8000500.0 8413.3 7302.9 8647.5 8636.3 9519.4 8274.9 9858.0 6283.1 6077.0 5668.0 True False 9837.505519750554 8027.883648815291 8853.689195826379 8152.436110262372 7654.141905584676 7840.949676871093 8924.17887426057 6118.175282494737 6165.864628445511 6695.5635321366835 1.4692572884318844 1.1989855088797041 1.3223217363753392 1.2175877461446134 1.1431661978632726 1.1710664291716302 1.3328495549967088 0.9137655483559141 0.9208880774338444 1.0 12.708989769756815 -7.767430107954426 24.999158016158603 0.9379950028103936 1.2545704300230622 0.7151404908459112 0.09239801204116958 79.29389219583416 330884.0556918384 0.04904549816920698 0.024532948069942002 1.7083226223680557e-08 7.767430107954426 0.3165754272126686 TEYLSNADER ddPTM_PC-9_AZD4547_30min_R2 2 TEYLSNADER 10 0 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2;A0A2R8Y5T0;H0YJ21 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ; 139.38 0.00055752 9810500.0 29328.0 33829.0 53485.0 60138.0 50761.0 47666.0 41146.0 52980.0 46968.0 42182.0 False True 38653.69393970395 44763.562687849175 52775.75395352179 46274.11322283799 43713.71134863962 44685.43748481681 44807.91428963611 44793.15835928519 49450.63259292758 40705.22101920156 0.9496003945407923 1.0997007648412769 1.296535251058489 1.1368102681719736 1.07390920019864 1.0977814728910988 1.100790345014936 1.1004278379462737 1.2148474164923613 1.0 15.312926231913833 -8.11670220351581 16.152489478299593 1.1240761368613117 1.1124171275493682 0.0 0.09315547393998 26.816616551987327 3618.7258018869416 0.06406197589478957 0.024211907990114363 7.643597267214021e-09 8.11670220351581 -0.011659009311943525 TEYLSNADER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TEYLSNADER 10 0 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2;A0A2R8Y5T0;H0YJ21 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 96.665 0.02508 3620600.0 20244.0 17885.0 24332.0 19524.0 22248.0 20040.0 22667.0 21867.0 19530.0 19295.0 False True 23670.909362774448 19660.504602152774 24912.167159623863 18430.13357766203 17888.664108604313 18989.067121596243 20519.817665131297 21293.01442000166 19815.589302869983 22793.03076086404 1.0385152203373382 0.8625664927329516 1.0929729977988891 0.80858635128536 0.7848304289273985 0.8331084760435081 0.900267186071811 0.9341896934813105 0.8693705330707329 1.0 14.476305150267414 -5.7769555358287965 24.996977616108463 0.8684772462584137 0.9844731079926688 0.32243888218098926 0.08001028993016947 280.79540189457384 452368.6911959605 0.022395206310225468 0.03335116391804231 1.671261713567309e-06 5.7769555358287965 0.11599586173425513 TFANFPSGS(ph)PVSASTLAR ddPTM_PC-9_AZD4547_30min_R2 1 TFANFPSGSPVSASTLAR 18 0 B1AKU2;P98170 B1AKU2 XIAP E3 ubiquitin-protein ligase XIAP 1 TFANFPS(0.208)GS(0.69)PVS(0.026)AS(0.031)T(0.045)LAR 71.592 0.0088705 4207100.0 6582.9 7617.5 9866.8 16525.0 13680.0 9116.6 7608.6 11634.0 7855.1 9760.5 True False 8676.125267173931 10079.707906668578 9735.959785147408 12715.416558704945 11780.768133988508 8546.537560820725 8285.750660188727 9836.232622724117 8270.304549495519 9418.787865864988 0.9211509369074369 1.0701703924343446 1.03367438823332 1.3500056206581956 1.2507732737758823 0.9073925097935988 0.8797045626452055 1.0443204330327907 0.8780646371141095 1.0 13.201325691376352 -6.778966984856099 24.998734013067295 0.9407794212231728 1.1295096931228932 0.3705514507006058 0.11935161572459482 289.08413957059577 412303.3625507634 0.04541421764287229 0.040139963170329675 1.6635391081028606e-07 6.778966984856099 0.18873027189972036 TFCGT(ph)PDYIAPEIIAYQPYGK ddPTM_PC-9_AZD4547_30min_R2 2 TFCGTPDYIAPEIIAYQPYGK 21 0 P17252;P05129-2;P05771;P05771-2;P05129 P17252 PRKCA;PRKCG;PRKCB Protein kinase C alpha type;Protein kinase C gamma type;Protein kinase C beta type 1 T(0.429)FCGT(0.571)PDY(0.001)IAPEIIAYQPYGK;T(0.392)FCGT(0.608)PDYIAPEIIAYQPYGK 124.08 5.5871e-06 10761300.0 42336.0 40053.0 64518.0 57299.0 46268.0 47617.0 57190.0 38011.0 39097.0 38790.0 True False 55797.96735649573 52999.34897089548 63662.44916468767 44089.60081072528 39844.48684381435 44639.50146256288 62279.799208289776 32137.273355885045 41163.587601892585 37431.9739067571 1.490649878509967 1.4158844281874274 1.7007505220876298 1.1778593595024485 1.0644505935772133 1.1925500261824211 1.663812850570705 0.8585513934140601 1.0996905400829495 1.0 15.191983507680538 -5.4028092548052165 0.23503022368359108 0.956107173643499 1.8831993514774128 0.34641133504308796 0.21968521236463784 10.047828508081178 0.6309353533216777 0.40133021285659026 2.7016227314501124 3.955403060111134e-06 5.4028092548052165 0.9270921778339138 TFCGT(ph)PDYIAPEIIAYQPYGK ddPTM_PC-9_Lapatinib_30min_R1 2 TFCGTPDYIAPEIIAYQPYGK 21 0 P17252;P05129-2;P05771;P05771-2;P05129 P17252 PRKCA;PRKCG;PRKCB Protein kinase C alpha type;Protein kinase C gamma type;Protein kinase C beta type 1 T(0.45)FCGT(0.55)PDY(0.001)IAPEIIAYQPYGK;T(0.074)FCGT(0.926)PDYIAPEIIAYQPYGK 130.17 5.048399999999999e-05 7175800.0 68515.0 97255.0 86317.0 69200.0 77772.0 78910.0 86223.0 84515.0 65135.0 49481.0 True False 67537.96353588781 97029.81202282959 79220.34945325552 74289.19884443274 73197.60386563491 75535.20324819432 90687.20504762075 88441.8754371763 57798.810398042624 58033.72492071191 1.1637709560804685 1.6719556112483862 1.365074352223464 1.2801039213996643 1.2612942554633624 1.301574271708281 1.5626638678030986 1.5239737852086743 0.9959521033159557 1.0 15.824603911442116 -8.273346126028734 24.31857177966115 0.9979758761125997 1.394463309621116 0.5343918698094012 0.14683245505694048 458.50363076983865 936442.9446634213 0.1393119922005111 0.037209126264336964 5.3291000510915076e-09 8.273346126028734 0.39648743350851634 TFCPAHK ddPTM_PC-9_Lapatinib_30min_R1 1 TFCPAHK 7 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 68.422 0.041263 2871300.0 39895.0 40450.0 44398.0 44445.0 39491.0 43016.0 42914.0 40188.0 40551.0 37773.0 False True 39326.08998415301 40356.3405102406 40747.76782123613 47713.633564173695 37168.217022293255 41176.30595519361 45135.876940185335 42055.28119350702 35983.719359039314 44302.01272064127 0.8876817907153489 0.9109369536937022 0.9197723832138862 1.0770082584067986 0.8389735531129893 0.9294454907690609 1.0188222649115792 0.9492860168385205 0.8122366716371267 1.0 15.435084624066215 -5.531349289933445 24.997751254038143 0.9465624766206594 0.9033206539038581 0.062313914980036134 0.0743740123840704 584.8790982593039 1726054.1490344456 0.020210906413524795 0.03507605383969269 2.942054476462412e-06 5.531349289933445 -0.043241822716801326 TFDHYCEYR ddPTM_PC-9_AZD4547_30min_R2 2 TFDHYCEYR 9 0 Q14204;A0A2R8YFZ7;A0A2R8Y6H2;A0A2R8YGC7 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ; 138.08 0.00076252 22294000.0 166448.0 182993.0 195148.0 222870.0 198388.0 189314.0 208305.0 214170.0 169599.0 194906.0 False True 219375.001666525 242141.9086268461 192560.2100125618 171490.76480717526 170845.2506261485 177476.16565267908 226843.74145974495 181074.94763699739 178563.6568967791 188082.40026476956 1.1663770844996866 1.2874245983992934 1.0238077020576548 0.9117852843528277 0.9083532025625164 0.9436085747674436 1.2060870189896016 0.9627426456813207 0.9493905684179348 1.0 17.521005330003504 -5.351740035173724 5.302249018572008 0.9852837799676929 1.2256160733752108 0.5619102248983252 0.0846884408480994 0.15585370074135674 6.9498663617754515 0.023669865184386536 0.05100365010280579 4.448974994776858e-06 5.351740035173724 0.24033229340751794 TFDHYCEYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TFDHYCEYR 9 0 Q14204;A0A2R8YFZ7;A0A2R8Y6H2;A0A2R8YGC7 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 109.44 0.0019879999999999997 5162800.0 55817.0 56694.0 67106.0 58188.0 70505.0 61424.0 65292.0 58799.0 52347.0 49171.0 False True 65265.71566399826 62322.20564240698 68706.06154092205 54927.915008041295 56690.05137437734 58202.817309227896 59107.06908685551 57255.58855269021 53112.47584420559 58085.3130625782 1.1236182129841368 1.0729425797406682 1.1828474001147518 0.9456420584126786 0.97597909670044 1.0020229596855768 1.0175906088889721 0.985715416408377 0.9143873561804664 1.0 15.825885802209184 -5.768390795015782 24.999998468103087 0.9793883476438923 1.1211167213651592 0.7695805876446495 0.03734954442161726 74.31157608256045 267254.0785436503 0.010513364510551418 0.015982515550111622 1.7045478804201571e-06 5.768390795015782 0.1417283737212669 TFDHYCEYR ddPTM_PC-9_Lapatinib_30min_R1 1 TFDHYCEYR 9 0 Q14204;A0A2R8YFZ7;A0A2R8Y6H2;A0A2R8YGC7 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 123.86 0.0012397999999999999 9101300.0 39640.0 47077.0 43059.0 37715.0 42430.0 42505.0 40877.0 43009.0 47067.0 27632.0 False True 39074.726330914316 46967.99609890225 39518.85523254668 40488.68691355181 39934.35082058959 40687.16023399445 42993.41104730289 45007.35515207383 41765.81882251739 32408.15438267438 1.2057066215348546 1.4492647604768156 1.2194108546234812 1.249336399582117 1.2322315658289622 1.255460578024958 1.3266232485700409 1.3887663771478165 1.2887441330150438 1.0 14.984069242266917 -10.770551537082437 3.2590627751184478 0.9989735767905393 1.2931684536789911 0.5809344771068856 0.0740202746222291 19234756.191874873 27202146.30321726 198269.27283414398 0.018501444988764507 1.6960883180305865e-11 10.770551537082437 0.2941948768884518 TFDHYCEYRR ddPTM_PC-9_AZD4547_30min_R2 2 TFDHYCEYRR 10 1 Q14204;A0A2R8YFZ7;A0A2R8Y6H2;A0A2R8YGC7 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ; 126.31 0.00013901 5204500.0 21426.0 10928.900000000001 26889.0 80443.0 42408.0 25270.0 19546.9 28964.0 18538.1 33381.0 False True 28239.02231151449 14461.4531987122 26532.434291039503 61898.10918196081 36520.38121536434 23689.862905243164 21286.53623263716 24488.27932650691 19517.98611971877 32212.341350385646 0.8766522744915719 0.4489413868246826 0.8236729520042124 1.9215650457901212 1.1337387996146737 0.7354281592747232 0.6608192804458257 0.7602142005183282 0.6059164066161586 1.0 14.975325906207088 -6.772501156737622 23.90655772033496 0.731760325438026 1.0448827999764108 0.1364269616020578 0.36090076165505053 283.1158898741729 611860.3478641887 0.1406929704604834 0.12535148146001468 1.6884913622063e-07 6.772501156737622 0.3131224745383847 TFDQLTPDESKER ddPTM_PC-9_AZD4547_30min_R2 1 TFDQLTPDESKER 13 1 Q15293 Q15293 RCN1 Reticulocalbin-1 0 73.219 0.028242000000000003 3566800.0 21401.0 15678.0 27291.0 45934.0 33303.0 26040.0 18783.0 29954.0 23455.0 27785.0 False True 28206.072831546797 20745.60689999998 26929.103508377375 35344.625973225615 28679.45330162421 24411.714683519273 20454.650612507554 25325.297574443724 24694.783415668455 26812.25560709581 1.0519843330182976 0.7737359811872634 1.004358003406869 1.3182265039973635 1.0696397096122807 0.9104685201143152 0.762884365726182 0.944541852261823 0.9210259583357482 1.0 14.710604972099617 -6.804036432268507 7.193593874922439 0.8944340178591782 1.0416221162537587 0.19880698444744538 0.13505994375340588 0.36961306229396473 49.15884034645801 0.05216461624971264 0.046444596058178966 1.570231074638413e-07 6.804036432268507 0.14718809839458047 TFEMSDFIVDTR ddPTM_PC-9_Lapatinib_30min_R1 1 TFEMSDFIVDTR 12 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 103.31 0.009835700000000001 20000000.0 10749.0 11488.0 13271.0 8432.9 9719.3 11808.0 8070.8 9877.7 10870.0 10793.0 False True 10595.717288874815 11461.400241820616 12179.909607541444 9053.083597329742 9147.629882879008 11302.999365792408 8488.66653327231 10336.654002316722 9645.706133825492 12658.555669231491 0.8370399882689056 0.9054271704693182 0.9621879403782638 0.7151750826782405 0.7226440458064017 0.8929138253320665 0.6705872893465469 0.8165745186428734 0.7619910506275862 1.0 13.627825183390863 -5.758555767948495 24.999999998062037 0.7850990471239037 0.9019392433765051 0.19722141264622506 0.09438648152770983 103.67858371362354 898839.5643781461 0.024518765442704097 0.04018480881070855 1.74358944798981e-06 5.758555767948495 0.11684019625260145 TFHHVYSGK ddPTM_PC-9_Lapatinib_30min_R1 1 TFHHVYSGK 9 0 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 0 55.567 0.038017 1978100.0 18114.0 13658.0 23987.0 18153.0 19751.0 21176.0 15226.0 19397.0 21175.0 13431.0 False True 17855.691038299232 13626.375740145022 22014.881452497662 19488.032176632805 18589.28501196005 20270.35184366702 16014.327778609835 20298.25543222991 18790.048517364743 15752.530454317437 1.1335125547023057 0.8650277350462331 1.3975457159940832 1.2371366132665718 1.1800824677577513 1.286799724174559 1.0166193822034888 1.2885710959959824 1.1928273093555446 1.0 13.943295978362693 -5.2518776225049075 24.99663472987993 1.2074270098925977 0.999270163911705 0.27779854524124903 0.12897622054181787 795.5489970114065 2079738.2621092622 0.0309942156675473 0.07969439285347123 5.599153547898398e-06 5.2518776225049075 -0.20815684598089268 TFIAIKPDGVQR ddPTM_PC-9_AZD4547_30min_R2 2 TFIAIKPDGVQR 12 1 Q32Q12;P22392-2;J3KPD9;P22392;E7ERL0;E5RHP0;F6XY72;C9K028;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Nucleoside diphosphate kinase A 0 ; 116.84 0.00085348 30054000.0 55286.0 43368.0 62136.0 76286.0 83718.0 56255.0 53518.0 74634.0 55811.0 55398.0 False True 72865.79797976253 57385.85789253725 61312.03604105884 58699.441306951034 72095.20077786922 52737.36595704208 58280.99832189635 63101.03021870314 58761.055519585294 53458.53288183889 1.3630340013411917 1.0734648857532072 1.1469083182020503 1.0980368921963553 1.3486191425646408 0.9865097883177821 1.0902094610549211 1.1803734000365738 1.0991894530563857 1.0 15.70613262429207 -6.784837271563166 24.999881975965643 1.0837143817295094 1.189366804757895 0.29131851366548545 0.10255744186611714 390.13048020608653 416838.80907240475 0.03581434197972074 0.03160327204461322 1.6412046109261783e-07 6.784837271563166 0.10565242302838551 TFIAIKPDGVQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TFIAIKPDGVQR 12 1 Q32Q12;P22392-2;J3KPD9;P22392;E7ERL0;E5RHP0;F6XY72;C9K028;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Nucleoside diphosphate kinase A 0 ; 121.29 0.00058815 26153000.0 60751.0 69793.0 56343.0 55917.0 72513.0 67184.0 69012.0 65992.0 66904.0 50908.0 False True 71034.94441305609 76721.58779413179 57686.4308020174 52784.15177535997 58304.59818892593 63660.75276932749 62474.68375638781 64259.77992430364 67882.34443006711 60137.21741249375 1.1812143539301552 1.2757754863827897 0.9592467574003982 0.8777285356138518 0.9695260389086927 1.0585915928345182 1.0388688809437405 1.0685525983607185 1.1287909110334773 1.0 15.875970494583585 -2.8779587356543668 7.141276094188137 1.0534230566739946 1.1577111932884174 0.0 0.110249465123931 0.0 0.0 0.027816039909041888 0.0 0.0013244673730429199 2.8779587356543668 0.10428813661442282 TFIAIKPDGVQR ddPTM_PC-9_Lapatinib_30min_R1 2 TFIAIKPDGVQR 12 1 Q32Q12;P22392-2;J3KPD9;P22392;E7ERL0;E5RHP0;F6XY72;C9K028;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Nucleoside diphosphate kinase A 0 ; 116.84 0.00085348 95937000.0 80419.0 74522.0 86150.0 70885.0 72563.0 67228.0 71674.0 71152.0 69433.0 67611.0 False True 79272.2103129615 74349.44888761807 79067.07954861692 76098.11936542804 68294.98700434696 64352.81515612229 75384.92901642462 74457.98167314641 61612.72437809616 79297.47126400557 0.9996814406482148 0.9376017633662741 0.9970945893769854 0.9596537966775017 0.8612505028939955 0.8115367883784347 0.9506599367518934 0.9389704423896821 0.7769822088395294 1.0 16.274987239765622 -6.162665317132318 5.363508107945709 0.8861698637077915 0.9743661144377338 0.2931177578943087 0.0637168244590852 0.2915851293979383 12.693526846723431 0.018629512736721452 0.024251977690064697 6.875981236091448e-07 6.162665317132318 0.0881962507299423 TFLDKDAQRLS(ph)PIPEEVPK ddPTM_PC-9_AZD4547_30min_R2 1 TFLDKDAQRLSPIPEEVPK 19 2 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 T(0.001)FLDKDAQRLS(0.999)PIPEEVPK 55.744 0.009666500000000001 120910000.0 29878.0 34861.0 40098.0 65798.0 48392.0 41104.0 34126.0 36570.0 30602.0 44577.0 True False 39378.58249899325 46129.136505989256 39566.27432043222 50629.287668966266 41673.60610672309 38533.7603821573 37163.14788917811 30918.94679499922 32219.559244778764 43016.372798182805 0.9154324257822308 1.0723623008013812 0.9197956904935431 1.1769771455743256 0.9687847532436199 0.8957928778175628 0.8639303007609241 0.7187715928551133 0.7490068815411571 1.0 15.392598259338492 -6.958589383900197 1.9600384730486338 0.8073670664812992 1.020802719156717 0.4128624241425485 0.1001590244842226 0.29133068624571534 2.2660131584855328 0.04278543595396495 0.03410941460257666 1.1000454172082346e-07 6.958589383900197 0.21343565267541786 TFLDKDAQRLS(ph)PIPEEVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TFLDKDAQRLSPIPEEVPK 19 2 Q96T23-3;Q96T23-2;Q96T23;H0YCN2;H0YER1 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 T(0.134)FLDKDAQRLS(0.866)PIPEEVPK;T(0.364)FLDKDAQRLS(0.636)PIPEEVPK 50.538999999999994 0.018636 75356000.0 94895.0 72846.0 83121.0 128374.0 132533.0 128725.0 115581.0 137760.0 122911.0 99531.0 True False 110958.84923831644 80077.66945755767 85102.91987814778 121181.62097412325 106564.11004610082 121974.43439258855 104632.33094602445 134143.94596878518 124708.34085023316 117575.18241303768 0.9437267879246976 0.6810762936029093 0.7238170346118118 1.0306734677086553 0.9063486686479861 1.037416501418611 0.8899185082992649 1.140920585583631 1.0606689123571753 1.0 16.84322404491619 -5.765215897189288 24.999781242883863 1.007185196635299 0.7726936431343023 0.5547804883736611 0.09285334378423644 67.62541753505961 447670.91034718335 0.025964645917788975 0.04023455042613345 1.7170545899442996e-06 5.765215897189288 -0.2344915535009966 TFLEGDWT(ph)SPSK ddPTM_PC-9_AZD4547_30min_R2 1 TFLEGDWTSPSK 12 0 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 TFLEGDWT(0.606)S(0.393)PS(0.001)K 103.43 0.0051293 18664000.0 72056.0 62416.0 80433.0 97671.0 94127.0 90572.0 92407.0 81542.0 84187.0 94192.0 True False 94968.3091420931 82590.75138859547 79366.40586601147 75154.45995190748 81059.0908002877 84908.51852210874 100631.04398392086 68941.55754875102 88636.95294883323 90894.36674981353 1.0448206257214276 0.9086454347157317 0.8731718884677118 0.8268329780961003 0.8917944389601459 0.934145003241171 1.107120799476028 0.7584799808167699 0.9751644256767438 1.0 16.471903264574514 -6.986433942889296 18.06719663509464 0.9515738059797176 0.9035186083749537 0.05550510069671877 0.09555800126961374 31.16434619406253 41497.26547582056 0.03416349973503793 0.030058726019874655 1.0317299958235253e-07 6.986433942889296 -0.048055197604763955 TFLEGDWT(ph)SPSK ddPTM_PC-9_Lapatinib_30min_R1 3 TFLEGDWTSPSK 12 0 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 TFLEGDWT(0.869)S(0.129)PS(0.002)K;TFLEGDWT(0.49)S(0.49)PS(0.02)K;TFLEGDWT(0.976)S(0.024)PSK 158.25 0.00020844 37610300.0 348560.0 310266.0 317550.0 324290.0 338690.0 279363.0 280611.0 279529.0 306248.0 265493.0 True False 343589.47048192436 309547.59813968674 291442.26477844757 348139.36839972733 318768.92009015963 267415.2957169599 295139.6645398317 292516.93781078537 271755.1253055921 311383.1113028143 1.1034300127722405 0.9941052899258158 0.9359604108233904 1.1180419096691736 1.0237193621595064 0.858798329164691 0.9478345286774846 0.9394116995841759 0.8727355962517674 1.0 18.248331172545406 -6.674692189525662 8.334011841321464 0.921649951145999 1.0325586190233558 0.45781119853187713 0.06054728270202809 0.24731341547881971 21.032991061466532 0.019895307036368035 0.019867052805999857 2.1149875268972504e-07 6.674692189525662 0.11090866787735676 TFLEGDWTS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 2 TFLEGDWTSPSK 12 0 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 TFLEGDWT(0.225)S(0.775)PSK;TFLEGDWT(0.031)S(0.968)PS(0.001)K 182.23 0.00048587 40270000.0 156336.0 119881.0 168920.0 198588.0 193219.0 171897.0 173733.0 166482.0 161732.0 150125.0 True False 206047.59600919115 158630.18884927267 166680.01042963268 152806.60475401516 166393.87705271385 161148.2534160101 189194.90043458322 140756.03227577423 170280.82333757821 144869.16944449392 1.4223012170173137 1.0949892890084612 1.150555436113655 1.0547903694068077 1.1485803203729075 1.1123709346435746 1.3059707676937606 0.9716079191694709 1.1754110553026997 1.0 17.14439107262949 -4.758765391748479 24.99728859009635 1.1183344873756622 1.422301621754138 0.5162556977076147 0.08975983254461518 57.31926514389473 535733.3072400475 0.020923532329804193 0.13935213649236006 1.742748061173995e-05 4.758765391748479 0.3039671343784758 TFLEGDWTS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 TFLEGDWTSPSK 12 0 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 TFLEGDWT(0.067)S(0.933)PSK;TFLEGDWT(0.069)S(0.925)PS(0.006)K;TFLEGDWT(0.069)S(0.93)PS(0.001)K;TFLEGDWT(0.413)S(0.559)PS(0.028)K;TFLEGDWT(0.056)S(0.751)PS(0.194)K;TFLEGDWT(0.222)S(0.769)PS(0.008)K 199.4 6.8381e-06 69729800.0 254663.0 247461.0 231855.0 318364.0 306788.0 286555.0 301772.0 297166.0 267333.0 226770.0 True False 297772.4160764787 272027.2926672247 237383.3025149841 300527.09723001457 246675.0936960854 271527.55134875263 273185.9715199196 289365.70737340313 271242.23938065197 267881.60588966805 1.1115821673815176 1.0154758172506406 0.8861500651625732 1.1218653712035465 0.9208362510626543 1.01361028670474 1.01980115660661 1.0801999876489605 1.0125452192950049 1.0 18.031235996256065 -7.530058058367081 24.393992617769797 1.0378236687286022 1.0077624446295848 0.01025378241998276 0.07078334716363019 567.4897430274045 1928178.149344633 0.032288985447973956 0.01869193691568281 2.9508147226066548e-08 7.530058058367081 -0.03006122409901746 TFLEGDWTS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 1 TFLEGDWTSPSK 12 0 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 TFLEGDWT(0.027)S(0.973)PSK 158.34 0.00046864 17548000.0 46857.0 48081.0 41899.0 48070.0 49718.0 40662.0 39425.0 43361.0 43542.0 40411.0 True False 46188.81058747859 47969.67139858786 38454.22595481718 51605.228156819154 46793.68498934889 38922.98104775159 41466.233591993434 45375.710357112985 38637.84144241299 47395.98750572723 0.9745299764436226 1.0121040603445874 0.8113392710758575 1.0888100633114415 0.9872921201123712 0.8212294562498191 0.8748891156025126 0.9573745109041115 0.8152133434870215 1.0 15.532477306803383 -6.733938368061136 24.984591403599843 0.8898988985740344 0.9741378027823565 0.19283986709405654 0.0827415609500438 357.0364201646659 324365.69059829845 0.02670289794441732 0.02669693623787861 1.8452772690330225e-07 6.733938368061136 0.08423890420832214 TFLPGEPPPCS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 TFLPGEPPPCSPR 13 0 F8WBW8;Q9P281 F8WBW8 BAHCC1 BAH and coiled-coil domain-containing protein 1 1 T(0.001)FLPGEPPPCS(0.999)PR;TFLPGEPPPCS(1)PR 69.456 0.030473 9342900.0 30439.0 42614.0 52256.0 62076.0 59296.0 48090.0 41696.0 62616.0 39778.0 50171.0 True False 40117.968829468366 56388.1421378109 51563.05129653616 47765.337264639515 51063.77392346362 45082.924697789625 45406.863224144945 52940.135972536795 41880.58387160353 48414.528560863895 0.8286349164597238 1.1646946446441804 1.065032601354656 0.9865909817668005 1.054720048740519 0.9311858658525204 0.9378768021475642 1.093476225963526 0.8650416541587042 1.0 15.563152425756817 -6.75405375089755 24.99685770686217 0.9696309156899361 1.0286298778308383 0.07017178008493086 0.0959009588818501 460.19218605116106 1557529.792406832 0.030786960443213437 0.03021100623300754 1.7617579871515154e-07 6.75405375089755 0.05899896214090217 TFLRPS(ph)PEDEAIYGPNTK ddPTM_PC-9_AZD4547_30min_R2 1 TFLRPSPEDEAIYGPNTK 18 1 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IT83;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 T(0.182)FLRPS(0.818)PEDEAIYGPNTK 56.036 0.017971 3069400.0 13128.0 11316.0 13975.0 22471.0 15236.0 16300.0 12223.0 12962.0 11013.0 14665.0 True False 17302.430920636714 14973.675703559107 13789.682368897205 17290.658123489196 13120.74439250356 15280.75842324747 13310.823320911455 10959.020737128249 11595.12469651489 14151.582813678593 1.2226498723459107 1.0580919393049022 0.9744268574373474 1.2218179656042747 0.9271573763339993 1.079791470992025 0.9405890136929079 0.7744024736607916 0.819351789066825 1.0 13.788675802906083 -7.423312528980974 3.1057170793827464 0.84737999288725 1.0750671207136544 0.4738361983234636 0.10296745680768014 0.2171095760294346 4.001633477196873 0.047915116173260046 0.02939149804639796 3.7730057844008156e-08 7.423312528980974 0.22768712782640443 TFNTS(ph)TGGLLLPSDTKR ddPTM_PC-9_AZD4547_30min_R2 2 TFNTSTGGLLLPSDTKR 17 1 P12956;B1AHC9;P12956-2 P12956 XRCC6 X-ray repair cross-complementing protein 6 1 T(0.172)FNT(0.172)S(0.554)T(0.102)GGLLLPSDTKR;T(0.041)FNT(0.297)S(0.493)T(0.168)GGLLLPSDTKR 126.55 1.6583e-05 21735000.0 47023.0 51028.0 59690.0 85320.0 80859.0 56222.0 53550.0 61522.0 67254.0 68627.0 True False 61975.3358608394 67521.803093073 58898.47159924681 65650.7921808596 69633.12357793683 52706.42945225881 58315.8462599041 52015.18853491777 70808.90913823782 66224.38961843308 0.9358385364957598 1.0195911730121676 0.8893773417709666 0.9913385772088139 1.0514724858793558 0.7958764098233131 0.8805795960658022 0.7854385496735438 1.0692270558659658 1.0 16.015075021073486 -6.75323572428334 24.99876058943965 0.8912114318167476 0.9757311723498011 0.12512834793328154 0.0899259122474423 325.4606360162238 991765.5730705941 0.02895331730514137 0.028475160515993584 1.7650795192126405e-07 6.75323572428334 0.08451974053305356 TFNTSTGGLLLPSDTKR ddPTM_PC-9_Lapatinib_30min_R1 2 TFNTSTGGLLLPSDTKR 17 1 P12956;B1AHC9;P12956-2 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 ; 103.75 0.00052795 7679000.0 36145.0 31922.0 35596.0 39920.0 39061.0 41443.0 40247.0 34303.0 39482.0 35750.0 False True 35629.56567181878 31848.086570281852 32669.434284533585 42855.8499692162 36763.508776880735 39670.57949835154 42330.792729916546 35896.842609258274 35035.121396108356 41929.339866119306 0.8497526024875243 0.7595656566970296 0.7791545106325865 1.0220969399006816 0.876796746485084 0.9461293601335006 1.0095745095219502 0.8561270633851418 0.8355753157091373 1.0 15.35567249617847 -5.738984569648399 24.999245427812113 0.9303136517967864 0.792498310056969 0.49200561313122115 0.06457285298629475 204.7272742001374 227923.89077350957 0.017683133621421494 0.03059916347864618 1.8239605059335714e-06 5.738984569648399 -0.13781534173981735 TFQARPLS(ph)ADLTK ddPTM_PC-9_Lapatinib_30min_R1 2 TFQARPLSADLTK 13 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 TFQARPLS(0.994)ADLT(0.006)K;T(0.001)FQARPLS(0.978)ADLT(0.021)K 113.11 0.0018413 25151000.0 152459.0 97053.0 92251.0 106723.0 109508.0 108008.0 104627.0 81154.0 104887.0 65527.0 True False 150284.9067024439 96828.27974141875 84666.47887915786 114571.76543749131 103066.95474101152 103388.74961894541 110044.07411615738 84924.71110724284 93073.52155092497 76853.25464076073 1.9554787549978028 1.2599112450608416 1.1016641946384562 1.490786121850535 1.3410877030879549 1.3452748371194032 1.4318726595320168 1.1050242635033605 1.2110550423138682 1.0 16.229818737118855 -4.760870179199284 24.99009893966615 1.271116769107087 1.9554795384524188 0.6687407155000988 0.14765859961602654 8.372978882657904 367288.5351490621 0.036487196112628566 0.21039175596157342 1.734322349880223e-05 4.760870179199284 0.6843627693453318 TFQEDSSPVVHQS(ph)LQEVSEPLTATK ddPTM_PC-9_AZD4547_30min_R2 2 TFQEDSSPVVHQSLQEVSEPLTATK 25 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 TFQEDS(0.006)S(0.004)PVVHQS(0.987)LQEVS(0.002)EPLTATK;T(0.001)FQEDS(0.036)S(0.036)PVVHQS(0.927)LQEVSEPLTATK 61.522 0.0014275 17791800.0 35728.0 29404.0 58226.0 91500.0 76864.0 68062.0 47628.0 66809.0 51764.0 64173.0 True False 47088.760811434186 38908.267973440474 57453.885195807474 70406.0886609078 66192.7603692173 63806.07238055645 51866.799732338266 56485.20416809136 54500.139361699556 61926.322802741015 0.7603997570052701 0.6282993436793941 0.9277780852388093 1.1369331404543117 1.0688953804033627 1.0303546132361703 0.8375565895871749 0.9121356090853046 0.8800803421721537 1.0 15.91826516063226 -5.356574012400101 5.217235696135865 0.9802674639803417 0.696078065427344 0.6132738005434535 0.08943985513034686 0.14730883164114433 6.217371290645568 0.02629350061369852 0.05670250918603435 4.3997296132086345e-06 5.356574012400101 -0.28418939855299774 TFQEDSSPVVHQS(ph)LQEVSEPLTATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TFQEDSSPVVHQSLQEVSEPLTATK 25 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 TFQEDS(0.001)S(0.002)PVVHQS(0.988)LQEVS(0.008)EPLT(0.001)ATK;T(0.001)FQEDS(0.031)S(0.025)PVVHQS(0.942)LQEVS(0.001)EPLTATK 78.642 6.1132e-05 14652200.0 41042.0 50009.0 74645.0 79355.0 96866.0 85534.0 95663.0 72438.0 84357.0 68017.0 True False 47989.59998355011 54973.56302203284 76424.81989273908 74908.9966223813 77885.8026583991 81048.44646599857 86601.10809985688 70536.5792544051 85590.56153723516 80347.94367772432 0.5972722858476185 0.6841937765393455 0.9511733143946919 0.9323075761943747 0.9693565148449739 1.0087183660988757 1.0778260666783708 0.877889041408793 1.0652489363080526 1.0 16.29397348143474 -5.185428032899546 1.9058630925563067 0.9909504504837057 0.5751294148233547 0.8639337282609956 0.05535999531169805 0.1366134769837401 0.8451977968907125 0.015172465548545925 0.07467237958344937 6.5248715592986425e-06 5.185428032899546 -0.415821035660351 TFS(ph)ATVR ddPTM_PC-9_AZD4547_30min_R2 5 TFSATVR 7 0 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 1 T(0.161)FS(0.833)AT(0.006)VR;T(0.228)FS(0.526)AT(0.246)VR;T(0.182)FS(0.814)AT(0.004)VR;T(0.18)FS(0.806)AT(0.014)VR;T(0.091)FS(0.801)AT(0.109)VR 88.37 0.017315999999999998 7071562500.0 297755.0 331093.0 420983.0 574622.0 446690.0 395709.0 385816.0 456723.0 339603.0 400033.0 True False 392434.89631125674 438112.3373734974 415400.4903545944 442151.7757214012 384674.8039306518 370965.25367514364 420152.876575371 386146.9548004499 357553.7212667347 386027.9664305697 1.0165970614510889 1.1349238279923832 1.0760891087648894 1.1453879360342298 0.9964946516377298 0.960980255149117 1.088400098211379 1.000308237693192 0.9262378696882411 1.0 18.558345844130052 -6.281583536694631 23.808490635510246 0.9983475796089573 1.0950004779375084 0.4747216392856305 0.05035186124433421 396.2442317126755 468321.8229098337 0.01555100613067169 0.017660634821793014 5.22897377015965e-07 6.281583536694631 0.09665289832855117 TFS(ph)ATVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 TFSATVR 7 0 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 1 T(0.194)FS(0.761)AT(0.045)VR;T(0.288)FS(0.689)AT(0.023)VR;T(0.44)FS(0.491)AT(0.069)VR;T(0.222)FS(0.777)AT(0.001)VR;T(0.174)FS(0.826)ATVR;T(0.225)FS(0.741)AT(0.034)VR 104.75 0.010853 3441910300.0 345059.0 385202.0 391346.0 455262.0 550025.0 507304.0 573668.0 513668.0 491400.0 407647.0 True False 403470.67347409547 423442.30884866917 400677.1728279697 429755.1461193194 442251.5496374987 480700.08518234844 519326.0140433473 500184.75927623315 498585.79536253563 481550.1741681238 0.8378580158777631 0.8793316492516366 0.8320569575540868 0.8924410563483232 0.9183914228698736 0.9982346824248504 1.0784463216953064 1.0386970789498737 1.035376627625233 1.0 18.877326599094005 -6.649687522543015 1.6894531473252734 1.0426033090816829 0.856784940519341 0.9195712021851464 0.024108007520663922 0.08925873914798321 0.5250505144861005 0.009634001477180541 0.009569369280607776 2.240332491332317e-07 6.649687522543015 -0.1858183685623419 TFS(ph)ATVR ddPTM_PC-9_Lapatinib_30min_R1 5 TFSATVR 7 0 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 1 T(0.325)FS(0.625)AT(0.05)VR;T(0.067)FS(0.925)AT(0.008)VR;T(0.105)FS(0.771)AT(0.124)VR;T(0.138)FS(0.862)ATVR;T(0.029)FS(0.969)AT(0.001)VR 93.14299999999999 0.014112999999999999 5414298600.0 343696.0 364507.3 429857.0 382521.0 459233.0 487677.0 422032.0 441300.0 479465.0 363843.2 True False 338794.8320138722 363663.3057421124 394515.8167560056 410652.8703926483 432221.8178268164 466820.1915406124 443882.75194156426 461804.40904485446 425462.60270971834 426733.01232941035 0.793926933762379 0.852203357216216 0.9245026875292808 0.962318026793884 1.012862387813505 1.0939397188710052 1.0401884530061045 1.0821858063523129 0.9970229403796129 1.0 18.702974197072542 -5.4906749743565335 0.9542029487112083 1.0482150459646558 0.7755896140129683 0.8807555256324966 0.0314594807641161 0.2622617207723819 0.3764367672571365 0.011898187534493293 0.05899294742206481 3.230911228502907e-06 5.4906749743565335 -0.2726254319516874 TFS(ph)DGLATR ddPTM_PC-9_AZD4547_30min_R2 2 TFSDGLATR 9 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 T(0.003)FS(0.997)DGLATR;T(0.134)FS(0.866)DGLATR 131.42 0.0012343 56371000.0 42118.0 62433.0 78537.0 110679.0 95490.0 93719.0 75763.0 96615.0 82997.0 75189.0 True False 55510.64789117739 82613.24630614235 77495.5480648359 85163.666523504 82232.86177738036 87858.73611462124 82505.76022762129 81685.37174183351 87384.05197826622 72556.65599575042 0.7650662386429248 1.1386032772924504 1.068069455535199 1.1737540182184245 1.1333606910191212 1.2108983649931033 1.1371218683569648 1.1258150009920214 1.2043561101187494 1.0 16.146820345758783 -4.761407232266267 23.445513632333686 1.1382799185659271 0.7650654131855248 0.7752292177649892 0.05927037862375415 0.15064109682203777 105780.33087982776 0.013813944831534444 0.07704511719245297 1.732178994370351e-05 4.761407232266267 -0.37321450538040235 TFS(ph)DGLATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TFSDGLATR 9 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 T(0.25)FS(0.749)DGLAT(0.001)R;T(0.137)FS(0.863)DGLATR;T(0.024)FS(0.976)DGLATR 98.898 0.0043143 43336400.0 70944.0 65340.0 64191.0 63514.0 91532.0 54226.0 60645.0 64980.0 41185.4 49609.7 True False 82953.41799212959 71826.52338298346 65721.55688572313 59955.51649516627 73596.96166795985 51382.293100582676 54900.266568222025 63274.34385200109 41787.65855987819 58603.545899830904 1.4155016854085778 1.2256344267248633 1.1214604146660136 1.0230697746113562 1.2558448561074564 0.8767778862461449 0.9368079307361576 1.0797016269314799 0.7130568281875715 1.0 15.838700339373306 -1.522878745294392 0.31657339122313066 0.9073317419973995 5.657293815973039 0.6024344399400522 0.12131528766668694 38.31695018498082 0.5470646379965446 0.11302089380244826 104.98429351631009 0.029999999999029157 1.522878745294392 4.749962073975639 TFS(ph)DGLATR ddPTM_PC-9_Lapatinib_30min_R1 2 TFSDGLATR 9 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 T(0.304)FS(0.696)DGLATR;T(0.003)FS(0.997)DGLATR 141.89 0.0006925 47210000.0 97718.0 81315.0 73924.0 62816.0 67771.0 62085.0 61024.0 65338.0 62432.0 73943.0 True False 96324.52340071333 81126.72011347875 67846.25407489216 67435.69818803307 63784.843022912406 59429.769277203726 64183.52412727476 68373.84200809587 55400.25072189448 86723.94902714582 1.1107026891794605 0.9354592476881437 0.7823243156703499 0.777590261335133 0.7354928337378508 0.6852751742036259 0.7400899618533793 0.7884078478332888 0.6388114395546427 1.0 16.40414283172283 -4.868359272954141 1.4519545913213092 0.7502839675702567 1.2215176576990312 0.5907588843549842 0.09023419099632513 0.6147970021816755 1.3553135248126624 0.024164277166618866 0.40407121373976135 1.3540687866215777e-05 4.868359272954141 0.4712336901287745 TFS(ph)EPGDHPGMLTSGK ddPTM_PC-9_AZD4547_30min_R2 2 TFSEPGDHPGMLTSGK 16 0 Q9HA47-3;Q9HA47;Q9HA47-4 Q9HA47-3 UCK1 Uridine-cytidine kinase 1 1 T(0.001)FS(0.999)EPGDHPGMLTSGK;T(0.118)FS(0.882)EPGDHPGMLTSGK 101.42 0.0091863 0.0 27704.0 24488.9 32197.0 42840.0 41370.0 38018.0 33397.0 49335.0 38327.0 35879.0 True False 36513.295721002374 32404.45801845958 31770.04674285392 32963.89987140212 35626.48959818014 35640.72845000136 36369.26830143826 41711.40935551782 40352.88697387873 34622.887130717645 1.0545999697583726 0.9359259352380853 0.9176024698029106 0.9520840866605934 1.0289866776179994 1.0293979330909317 1.0504400792495208 1.204735156777587 1.1654974589937475 1.0 15.079438412616167 -7.106994365597013 1.357824307995268 1.132732905686061 0.9652788555847535 0.4772282668530764 0.06394463446581512 0.3352764889246107 1.2353776588883454 0.036285157328311037 0.024162234698443735 7.816379452527597e-08 7.106994365597013 -0.16745405010130765 TFS(ph)FLMNR ddPTM_PC-9_AZD4547_30min_R2 1 TFSFLMNR 8 0 Q8N1W1-5;Q8N1W1-4;Q8N1W1-3;Q8N1W1;Q8N1W1-6 Q8N1W1-5 ARHGEF28 Rho guanine nucleotide exchange factor 28 1 T(0.28)FS(0.72)FLMNR 96.14299999999999 0.0062104 1739200.0 14693.0 14320.0 19524.0 22968.0 17354.0 15462.0 13227.0 19974.0 13571.0 17746.0 True False 19365.068366614494 18948.659957137366 19265.099003245017 17673.08245206264 14944.696651844779 14495.158695721011 14404.177375905732 16887.47725685847 14288.33535425439 17124.717941462026 1.1308255372620284 1.1065093172284752 1.124987814053319 1.0320218127081047 0.872697389990931 0.8464465660263882 0.8411337007210277 0.986146301187878 0.8343690916893736 1.0 14.063792605415014 -6.067881276778229 3.0093824336662713 0.8908422812491178 1.11821735008558 0.7750451076963085 0.054636380332439234 0.11556389404269493 2.0548875129400543 0.016432475976461053 0.02316981194721956 8.553004946992046e-07 6.067881276778229 0.2273750688364623 TFS(ph)FLMNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TFSFLMNR 8 0 Q8N1W1-5;Q8N1W1-4;Q8N1W1-3;Q8N1W1;Q8N1W1-6 Q8N1W1-5 ARHGEF28 Rho guanine nucleotide exchange factor 28 1 T(0.001)FS(0.999)FLMNR;T(0.054)FS(0.946)FLMNR 82.645 0.014244999999999999 10178300.0 105138.0 85478.0 81655.0 96233.0 111152.0 88317.0 98343.0 106743.0 79935.0 65700.0 True False 122935.78682984467 93963.69093557795 83601.96487831176 90841.37700159557 89372.56351130841 83685.5010468071 89027.2390983371 103941.10935355743 81103.89815283746 77610.8899190863 1.5840017677675402 1.2107024031490987 1.0771937413096473 1.170472044532704 1.1515466915079098 1.078270087278395 1.147097259046417 1.3392593418516636 1.0450066767356077 1.0 16.243971476935855 -4.769861848242181 3.5779825321393885 1.1396609673280746 1.6414727649356209 0.7062189164574638 0.08790797282214359 0.15713940816780655 3.342854585914557 0.02150848346339179 0.21726616916561695 1.6987839601926112e-05 4.769861848242181 0.5018117976075462 TFS(ph)FLMNR ddPTM_PC-9_Lapatinib_30min_R1 3 TFSFLMNR 8 0 Q8N1W1-5;Q8N1W1-4;Q8N1W1-3;Q8N1W1;Q8N1W1-6 Q8N1W1-5 ARHGEF28 Rho guanine nucleotide exchange factor 28 1 T(0.003)FS(0.997)FLMNR;T(0.006)FS(0.994)FLMNR;T(0.301)FS(0.699)FLMNR 105.2 0.003846 7203400.0 69325.0 57571.0 63404.0 50081.0 51322.5 57703.0 48705.5 46962.0 50803.2 47983.1 True False 68336.41278735202 57437.697886651666 58191.16786651777 53764.123805318544 48303.81145391724 55235.17720226279 51227.232472158204 49144.02596320979 45081.2086345872 56276.914901538155 1.2142885392156466 1.0206262725514434 1.034014888135371 0.9553495229684147 0.8583237289824678 0.981489075918643 0.9102708021892306 0.8732537319999144 0.8010604119550812 1.0 15.780255621801095 -1.5228787453080972 0.5088399591540027 0.8925113481421592 11.47617473826182 0.7104729905122174 0.05925219791478226 58.881544555809434 0.6103949772545796 0.03157568671402951 669.0331059866027 0.029999999998082432 1.5228787453080972 10.58366339011966 TFS(ph)LDAVPPDHSPR ddPTM_PC-9_AZD4547_30min_R2 6 TFSLDAVPPDHSPR 14 0 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 T(0.179)FS(0.821)LDAVPPDHSPR;T(0.18)FS(0.82)LDAVPPDHSPR;T(0.002)FS(0.998)LDAVPPDHSPR;T(0.202)FS(0.798)LDAVPPDHSPR;T(0.068)FS(0.932)LDAVPPDHSPR;T(0.202)FS(0.798)LDAVPPDHSPR 170.26 2.2798e-05 284282600.0 195203.0 165259.0 234067.0 318161.0 265852.0 226053.0 198019.0 252779.0 202049.0 247976.0 True False 257273.49352536933 218675.73993411774 230963.1186433389 244813.8969884491 228943.0387395546 211917.87017486824 215642.30738636662 213717.81383355556 212728.89764879105 239294.43571801967 1.0751336225324348 0.9138354566330216 0.9651838244809912 1.0230655646207063 0.9567420071954245 0.8855946421779256 0.9011588871229572 0.8931165206256482 0.8889838871952168 1.0 17.868427324905575 -6.577306023828175 5.053494389319109 0.9068231639232497 0.9870018659537421 0.3620810931660302 0.04960442581114269 0.2120606209856519 11.471465222696283 0.015928279730253354 0.016081154609931616 2.646634541199998e-07 6.577306023828175 0.08017870203049238 TFS(ph)LDAVPPDHSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TFSLDAVPPDHSPR 14 0 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 T(0.137)FS(0.863)LDAVPPDHSPR;T(0.178)FS(0.822)LDAVPPDHSPR;T(0.214)FS(0.786)LDAVPPDHSPR 120.32 5.0126999999999996e-05 72319400.0 89219.0 96106.0 100242.0 125845.0 176330.0 184128.0 182785.0 200140.0 164520.0 148045.0 True False 104322.01454442683 105646.76853757308 102632.14944990184 118794.31264499457 141779.40229549614 174472.003541181 165470.28155119874 194886.53706585834 166925.79375873855 174884.3865764244 0.5965198871474907 0.6040949143930895 0.5868571314972799 0.679273404393259 0.8107036029402122 0.9976419676832432 0.9461695511559478 1.1143735634781382 0.9544922621539575 1.0 17.41604196773153 -6.455875670244471 1.4760642739078782 1.0175868325970912 0.5932775892336644 0.9429529726376032 0.04497725025780256 0.07907278794354684 0.35004929243007776 0.016938421047611518 0.019813798617798316 3.5004536361682385e-07 6.455875670244471 -0.4243092433634268 TFS(ph)LDAVPPDHSPR ddPTM_PC-9_Lapatinib_30min_R1 3 TFSLDAVPPDHSPR 14 0 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 T(0.189)FS(0.811)LDAVPPDHSPR;T(0.228)FS(0.772)LDAVPPDHSPR;T(0.207)FS(0.793)LDAVPPDHSPR 175.01 0.00012211 188379000.0 99717.0 97183.0 110149.0 107679.0 133218.0 168564.0 179600.0 144689.0 205668.0 152395.0 True False 98295.01729414186 96957.97873440561 101092.97440743574 115598.0728666139 125382.37915666524 161354.91066187603 188898.80921045085 151411.77915316322 182503.50405994686 178736.27269642678 0.5499444282419957 0.5424639177694117 0.5655985373441031 0.6467521735946152 0.7014937553812591 0.9027541428925734 1.0568577175785945 0.8471239601730275 1.0210770388499626 1.0 17.447472918715107 -6.596706063265447 1.5088718128316263 0.9764672851227366 0.5585758192424569 0.9173213172732164 0.05618880506606004 0.10251671683248811 0.4814999438745443 0.023256288862465595 0.024169323107866236 2.531010441046694e-07 6.596706063265447 -0.4178914658802797 TFS(ph)LTEVR ddPTM_PC-9_AZD4547_30min_R2 3 TFSLTEVR 8 0 O95239;O95239-2 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 T(0.001)FS(0.995)LT(0.004)EVR;TFS(0.987)LT(0.013)EVR;T(0.006)FS(0.982)LT(0.012)EVR 133.99 0.0036912 196365600.0 93659.2 91935.0 138540.2 188898.0 147551.0 132446.0 109449.8 143982.0 106704.1 115704.0 True False 123440.87736761833 121651.19086308844 136703.0664274413 145350.48454500738 127066.0905656533 124164.13068254224 119190.62016764226 121732.8902772104 112344.26088526241 111653.23817755684 1.1055736437425683 1.0895446728525002 1.2243537998427678 1.301802678699416 1.1380421440494735 1.1120513180736409 1.0675070612649773 1.0902763973905027 1.0061890073139363 1.0 16.768665567379173 -7.3353249177103255 1.1396696947534117 1.022407063595524 1.1766110735766078 0.5282957457778545 0.059890280027508964 0.4666086855120018 1.1634447294748678 0.04774028817493527 0.02553128124751945 4.6203522009728605e-08 7.3353249177103255 0.15420400998108375 TFS(ph)LTEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 TFSLTEVR 8 0 O95239;O95239-2 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 T(0.008)FS(0.868)LT(0.124)EVR;T(0.141)FS(0.788)LT(0.072)EVR;TFS(0.846)LT(0.154)EVR;T(0.025)FS(0.702)LT(0.272)EVR;TFS(1)LTEVR;T(0.001)FS(0.922)LT(0.076)EVR;T(0.002)FS(0.533)LT(0.464)EVR 145.46 0.001418 125200240.0 125978.8 110956.0 132602.3 169724.5 274140.7 368815.0 421115.0 446457.1 386863.0 300104.0 True False 147304.5226452817 121970.97839734203 135764.04172902287 160215.38651925322 220424.79777048083 349473.6921382994 381223.93859142164 434738.0741853982 392520.1395021098 354510.47957804275 0.4155152841197004 0.34405464837744254 0.3829619984453392 0.4519341338229271 0.6217723042569635 0.9857922748976605 1.0753530870093733 1.226305283564104 1.1072173098220062 1.0 18.435468749607693 -6.6769049989430505 1.6225983612523276 1.1284150587704134 0.3804969454205151 0.9701204073389849 0.05717020274774186 0.054145334810028686 0.2949545875914608 0.02342095461149798 0.022780599587945722 2.104238687466841e-07 6.6769049989430505 -0.7479181133498982 down TFS(ph)LTEVR ddPTM_PC-9_Lapatinib_30min_R1 4 TFSLTEVR 8 0 O95239;O95239-2 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 T(0.033)FS(0.856)LT(0.111)EVR;TFS(0.998)LT(0.002)EVR;TFS(0.846)LT(0.154)EVR;T(0.013)FS(0.679)LT(0.308)EVR 145.46 0.001418 97854900.0 40859.3 27201.899999999998 46429.0 37586.2 103366.1 127605.6 157405.3 126653.5 148189.0 123012.3 True False 40276.63888932209 27138.915671829745 42611.78684112287 40350.41453188758 97286.30922357165 122148.2059511822 165554.9762439519 132538.28398133378 131498.39432064994 144274.81215141373 0.2791661156145017 0.18810570789964334 0.29535153229936345 0.2796774705867617 0.6743124996861647 0.8466356956541377 1.1474974305993553 0.9186515789203545 0.9114438782470555 1.0 17.138459927030418 -6.4875478581581705 1.7553235190507193 0.986700871023948 0.23986779792447144 0.9545456029808073 0.07271972256921613 0.06800887773190048 0.421848417567123 0.02795671727872049 0.031323417530734234 3.254259204052009e-07 6.4875478581581705 -0.7468330730994766 down TFS(ph)WASVTSK ddPTM_PC-9_AZD4547_30min_R2 1 TFSWASVTSK 10 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 1 T(0.347)FS(0.642)WAS(0.011)VTSK 113.61 0.0012824000000000002 4732100.0 15664.0 21878.0 18735.0 32439.0 27172.0 23474.0 24211.0 29680.0 19084.0 25452.0 True False 20644.826168559823 28949.63565239185 18486.561658768453 24960.68972755401 23399.636822860783 22006.167069160176 26365.732097078217 25093.6379785501 20092.74127924181 24560.933226985868 0.8405554454208077 1.17868630580307 0.7526815649845376 1.016276112022035 0.9527177410812252 0.8959825290751293 1.0734825038370024 1.0216891087419648 0.8180772731048056 1.0 14.584077758513477 TFS(ph)WASVTSK ddPTM_PC-9_Lapatinib_30min_R1 2 TFSWASVTSK 10 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 1 T(0.012)FS(0.986)WAS(0.002)VTSK;T(0.018)FS(0.971)WAS(0.008)VT(0.003)SK 124.39 0.00041448 8488700.0 76797.0 67665.0 76037.0 56139.0 70554.0 59526.0 73073.0 61736.0 61465.0 64189.0 True False 75701.86069715484 67508.32584982534 69785.53137130804 60267.64933421413 66404.15243450098 56980.211741883395 76856.36239106508 64604.47993834849 54542.16444485587 75283.98312353388 1.0055506836419013 0.8967156498487943 0.9269638570636811 0.8005374693754 0.8820488725408971 0.7568703112903082 1.0208859733809657 0.8581437545930409 0.724485636677291 1.0 16.200055339716734 -4.290658905846352 1.1450421552621477 0.8630958234890306 1.2622472146744865 0.16641258479799204 0.09043748897032225 7.608787877916089 3.8732364188095874 0.026718018088828597 4.788360004924947 5.12083867447913e-05 4.290658905846352 0.39915139118545595 TFSAT(ph)VR ddPTM_PC-9_Lapatinib_30min_R1 1 TFSATVR 7 0 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 1 T(0.05)FS(0.23)AT(0.72)VR 104.75 0.025195 424290000.0 65236.0 62329.0 87252.0 69369.0 81757.0 82814.0 74069.0 88485.0 105180.0 63985.0 True False 64305.72267718277 62184.68102998236 80078.4773624599 74470.62766820034 76948.21400044652 79272.23826886281 77903.93039759966 92596.33613037372 93333.52080549813 75044.7219953467 0.856898672783013 0.8286349709422369 1.0670767408189656 0.9923499706324189 1.0253647685605105 1.056333292483624 1.0381000598873595 1.233882059502004 1.2437053309529946 1.0 16.195462988118877 -5.074439440819855 0.45418501559835284 1.14769901249899 0.6629859302125467 0.5696236080541892 0.08351022931663282 2.8530812446619733 0.5571374319293501 0.06457400396177407 0.72503910758191 8.424818611643755e-06 5.074439440819855 -0.4847130822864434 TFSATVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TFSATVR 7 0 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 0 97.473 0.019500999999999998 0.0 17667.0 19763.0 23833.0 24854.0 34649.0 28729.0 29115.0 26027.0 29524.0 24550.0 False True 20657.674160844494 21724.940030883146 24401.269107155833 23461.510957755174 27859.777179927674 27222.400665485955 26357.016425653936 25343.818827885993 29955.73264607954 29000.720662306925 0.7123158904010917 0.7491172472523995 0.8414021634597125 0.8089975153013621 0.9606580989602038 0.9386801446237057 0.9088400503064364 0.8739030703063213 1.0329306293761822 1.0 14.823801130928215 -3.14504677064264 0.2848568804113901 0.990917449712528 8.247550124418879e-18 0.7984162487904259 0.04496831740846972 9.521806134518446 0.3024059930623599 0.0517308715648233 3.916731361786127 0.0007160662904579635 3.14504677064264 -0.990917449712528 TFSATVR ddPTM_PC-9_Lapatinib_30min_R1 1 TFSATVR 7 0 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 0 120.62 0.00069096 0.0 41922.0 38209.0 51611.0 54045.0 50103.0 63336.0 56653.0 54334.0 56971.0 49281.0 False True 41324.18459244675 38120.52940805395 47367.74280422134 58019.649588834865 47156.04004628799 60627.266923427196 59586.21513474206 56858.555996018964 50554.32604877386 57799.15518719513 0.7149617405065765 0.6595343700888417 0.8195230994434194 1.003814837793487 0.8158603684355403 1.0489299839603643 1.030918444080353 0.9837264197352049 0.8746551032630613 1.0 15.81876078549078 -5.530831101352942 3.1576975748766203 0.9647704826595799 0.6892177327346719 0.7256480507278301 0.06892069384854568 0.126273869738177 2.5834249743063773 0.019548055884672545 0.04101260200170706 2.9455669523928363e-06 5.530831101352942 -0.27555274992490797 TFSLT(ph)EVR ddPTM_PC-9_Lapatinib_30min_R1 1 TFSLTEVR 8 0 O95239;O95239-2 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 T(0.003)FS(0.375)LT(0.622)EVR 125.16 0.008342700000000002 64964000.0 17616.0 12340.0 14932.0 15911.0 40155.0 49026.0 56386.0 57119.0 66654.0 57328.0 True False 17364.792609621254 12311.427488167348 13704.348599186862 17081.148017540047 37793.16184776749 46929.27226518789 59305.39118118308 59772.9572631613 59146.72462226348 67237.0684152416 0.25826219106371573 0.18310476316627358 0.2038213283564323 0.25404361641781537 0.5620881864504427 0.6979672578132473 0.8820341603076118 0.8889881529934712 0.8796743525013031 1.0 16.03696920294873 -6.6197051500774995 1.2071260786553486 0.9176347568710361 0.19353181076999385 0.979728792188043 0.0444783801136337 0.05641406285180966 0.17341420931702792 0.02070230933576847 0.021358762147184646 2.400462080525432e-07 6.6197051500774995 -0.7241029461010423 down TFSVWYVPEVTGTHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TFSVWYVPEVTGTHK 15 0 Q60FE5;P21333-2;P21333;A0A087WWY3;F8WE98 Q60FE5 FLNA Filamin-A 0 76.156 0.011948 2534800.0 23698.0 28268.0 31119.0 34163.0 41444.0 30799.0 34582.0 34941.0 30834.0 23823.0 False True 27709.603343164807 31074.260223296307 31860.994979464704 32248.9578679404 33323.34570824333 29183.846221459215 31306.14260800156 34023.83577304969 31284.888917803026 28141.921317235774 0.9846379367919634 1.1041982483358233 1.132154220044356 1.1459401618108154 1.1841176489905878 1.0370239434784185 1.1124379979283017 1.209008986611425 1.111682765548858 1.0 14.78043320777651 -4.760511974903484 3.4899942802957913 1.124301314629501 0.9639522721581096 0.30184323659620516 0.05887059345277089 0.3690244960012123 7.166213524554299 0.01445697657480011 0.1625501429925701 1.7357534018764566e-05 4.760511974903484 -0.16034904247139126 TFSVWYVPEVTGTHK ddPTM_PC-9_Lapatinib_30min_R1 1 TFSVWYVPEVTGTHK 15 0 Q60FE5;P21333-2;P21333;A0A087WWY3;F8WE98 Q60FE5 FLNA Filamin-A 0 69.729 0.021118 3255500.0 30535.0 27273.0 41496.0 25907.0 31999.0 31428.0 32158.0 26014.0 27564.0 27813.0 False True 30099.565300566806 27209.851044148123 38084.359059192175 27812.287203218508 30116.88173245453 30083.89770224627 33822.983889697556 27222.705408776048 24459.452058212133 32620.439991507035 0.9227210089257976 0.8341350101725299 1.1674998580370992 0.8526030675999353 0.9232518549809775 0.9222407088953684 1.03686473568424 0.8345290687637467 0.7498198082116712 1.0 14.993488621111332 -7.795041530298209 24.79492484582305 0.8441306544541438 0.9491415419414985 0.12396220914215861 0.10644053110388849 319.0630110225023 235431.18130861118 0.05621514102682964 0.02700744696415728 1.603092084400246e-08 7.795041530298209 0.10501088748735465 TFSVYS(ph)SSR ddPTM_PC-9_AZD4547_30min_R2 2 TFSVYSSSR 9 0 H0YCB7;H0YEE1;Q9UID3-2;Q9UID3 H0YCB7 VPS51 Vacuolar protein sorting-associated protein 51 homolog 1 TFS(0.001)VYS(0.494)S(0.494)S(0.012)R;TFSVYS(0.495)S(0.495)S(0.01)R 102.95 0.0030111 16975300.0 23128.0 27896.0 27750.0 34392.0 33992.0 45265.0 29535.0 34179.0 29346.0 27762.0 True False 30482.222907715255 36912.83646398771 27382.01686847209 26463.45575110322 29272.797544629924 42434.572394374045 32163.55778312359 28897.420905285162 30897.1696489536 26790.06083009515 1.1378183536437678 1.37785564198947 1.022096106542317 0.9878087220083864 1.0926737990734885 1.5839670041623914 1.200578004921587 1.0786620115779157 1.1533071852619554 1.0 14.709410236548218 -8.541721342969556 1.3608751660705023 1.0072512651608214 1.1953458911948023 0.10184400986806785 0.1681185824632958 1.2253290716466874 4.985422409581723 0.17106355702827944 0.05159589309895047 2.8726231564093264e-09 8.541721342969556 0.18809462603398086 TFSVYS(ph)SSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TFSVYSSSR 9 0 H0YCB7;H0YEE1;Q9UID3-2;Q9UID3 H0YCB7 VPS51 Vacuolar protein sorting-associated protein 51 homolog 1 TFSVYS(0.915)S(0.085)SR 121.61 0.0016064 6027500.0 21300.0 23961.0 25163.0 27221.0 28464.0 20537.0 16144.0 19410.0 21769.0 15466.0 True False 24905.669305823718 26339.689727267683 25762.981351208902 25695.895621672713 22886.683530533675 19460.00356667773 14614.723447561651 18900.508066594957 22087.330442098137 18269.863371211366 1.3632104849272537 1.4417015164312779 1.4101354141380593 1.4064634802996323 1.2527014058899444 1.0651422603051164 0.7999361106657601 1.0345183038630341 1.208948857105419 1.0 14.15717822454863 -6.620259478192346 2.4576039267186105 1.0050315931857856 1.407024580805694 0.7878334562798435 0.09443076847406179 0.13398390351480868 1.6457140186145705 0.03643398474204581 0.036735105675310686 2.397400114905519e-07 6.620259478192346 0.4019929876199084 TFSVYS(ph)SSR ddPTM_PC-9_Lapatinib_30min_R1 1 TFSVYSSSR 9 0 H0YCB7;H0YEE1;Q9UID3-2;Q9UID3 H0YCB7 VPS51 Vacuolar protein sorting-associated protein 51 homolog 1 TFS(0.004)VYS(0.497)S(0.497)S(0.001)R 97.47200000000001 0.0047726999999999995 7081200.0 17405.0 13896.0 17075.0 15578.0 18091.0 18496.0 12811.0 11375.0 15278.0 11128.0 True False 17156.80150831391 13863.824665767686 15671.159411406077 16723.658086684605 17026.922948274485 17704.96919628187 13474.290895295588 11903.524026479103 13557.230755527678 13051.45997287205 1.3145503678496482 1.0622432045598091 1.2007207962924586 1.281363013903836 1.3045991010711127 1.3565508558492547 1.0323972125189371 0.912045399612076 1.0387520464152586 1.0 13.671923579280232 -7.400124736720946 5.576181717881391 0.9800994410720246 1.2450809061207053 0.706900016347273 0.08147811593339616 0.13708433388860647 5.671012541216912 0.03721319656543135 0.02469116277479962 3.97992843859516e-08 7.400124736720946 0.2649814650486807 TFSWAS(ph)VTSK ddPTM_PC-9_AZD4547_30min_R2 1 TFSWASVTSK 10 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 1 T(0.002)FS(0.003)WAS(0.992)VT(0.003)SK 97.911 0.0049625 3836600.0 17414.0 17643.0 30901.0 41591.0 36290.0 27986.0 33948.0 25581.0 28244.0 35771.0 True False 22951.289766298574 23345.754722330632 30491.232549645258 32002.83752454447 31251.759910997276 26236.03099588978 36969.30623400978 21628.044242900607 29736.920178731198 34518.66817784501 0.6648949967608924 0.6763225800616072 0.8833258685575631 0.9271168099435753 0.9053582180512828 0.7600533966350637 1.0709945715037077 0.6265607969423935 0.8614735662894764 1.0 15.075089182122966 -5.257869883920745 21.639836328286215 0.8712404989740293 0.6706085920688047 0.34170841125505647 0.11545750502215822 51.88596748496501 314525.32707770803 0.028705183942039435 0.06955669055190629 5.5224286830826965e-06 5.257869883920745 -0.2006319069052246 TFSWAS(ph)VTSK ddPTM_PC-9_Lapatinib_30min_R1 1 TFSWASVTSK 10 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 1 TFS(0.063)WAS(0.831)VT(0.08)S(0.026)K 74.611 0.025639999999999996 4521600.0 32912.0 26457.0 27415.0 23077.0 30578.0 23390.0 24611.0 21051.0 21829.0 21778.0 True False 32442.668844678385 26395.74044201324 25161.044524960336 24774.159562615263 28779.462158661056 22389.664224753087 25885.237157452146 22029.10631045377 19370.388150439434 25542.298282639047 1.270154646448925 1.0334128961274511 0.9850736314539931 0.9699267970515447 1.1267373765743818 0.8765720287579295 1.0134263123473972 0.8624559178931376 0.7583651218890265 1.0 14.640600723375835 -1.5228787452803376 0.44487401708018504 0.9111592922123865 7.830254851403288 0.5240340554121494 0.09331073734149717 73.83847529136274 0.8996077247573305 0.06070419627414377 462.5403175531882 0.029999999999999995 1.5228787452803376 6.919095559190902 TFSWASVT(ph)SK ddPTM_PC-9_AZD4547_30min_R2 1 TFSWASVTSK 10 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 1 T(0.01)FS(0.015)WAS(0.401)VT(0.569)S(0.005)K 87.363 0.026101 3951200.0 19444.0 22212.0 22683.0 36418.0 27642.0 22989.0 26971.0 24393.0 22322.0 25234.0 True False 25626.787539675504 29391.594620665866 22382.20859919109 28022.392752491167 23804.385435651337 21551.494195830433 29371.36675024975 20623.622345376418 23501.89534873381 24350.56534063183 1.0524103724571086 1.207018983317914 0.9191658709395013 1.150790232608376 0.9775701345188431 0.8850510817450792 1.2061882892402547 0.8469463462913297 0.9651478320923452 1.0 14.571667646914888 -5.632240036174099 0.5930533138557326 0.9717191718122062 1.1414984885039685 0.1314018822333003 0.11464696893809227 3.2107736656370096 1.6687590316606429 0.06864145651730633 0.3315044078017631 2.332168707686606e-06 5.632240036174099 0.16977931669176227 TFSWASVTS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TFSWASVTSK 10 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 1 TFS(0.001)WAS(0.113)VT(0.251)S(0.635)K 109.39 0.0018908000000000002 3663900.0 20483.0 17588.0 17237.0 20091.0 22184.0 22264.0 22079.0 26226.0 22728.0 16791.0 True False 23950.367342309255 19334.02040495738 17647.995451686536 18965.366405900833 17837.20444917647 21096.436646467984 19987.517281882654 25537.595288743916 23060.354002848377 19835.075382517134 1.2074754887707353 0.9747389426106547 0.8897367472191048 0.9561529785068086 0.8992758588101151 1.0635924613154044 1.0076854711376537 1.2874967599696168 1.162604807802951 1.0 14.275766259955606 -7.644087386986969 8.157175875778286 1.1681822167293223 0.9902136026946712 0.2858386511832385 0.10721851498815166 0.2652884779423362 17.73513048422106 0.0507323310530223 0.029145274984099512 2.2694081647658095e-08 7.644087386986969 -0.17796861403465114 TFTAWCNSHLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TFTAWCNSHLR 11 0 O43707;F5GXS2;O43707-3;K7EP19;P12814-4;P12814-3;P12814;P12814-2;P35609-2;P35609;A0A494C1A0;Q08043;G3V2N5;A0A494C033;A0A494C166;A0A494C0Q3 O43707;P12814-4 ACTN4;ACTN1;ACTN2;ACTN3 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2;Alpha-actinin-3 0 ; 124.6 0.00042247 10860400.0 108118.0 106996.0 115918.0 134519.0 123581.0 100381.0 116693.0 97202.0 97938.0 85027.0 False True 126420.24197216213 117617.8557680702 118681.92474146334 126982.33654648202 99366.19018363139 95116.84364934897 105638.99425584199 94650.55049403195 99370.15796950745 100441.72202663831 1.2586427176012973 1.1710059663938914 1.1815998605637956 1.2642389435816805 0.9892919812473777 0.9469853934216986 1.051744156953276 0.942342968482057 0.9893314846110796 1.0 16.615999142706798 -6.270196919667633 24.769587129357696 0.9850080098417445 1.2127905928157372 0.8932654648570146 0.03930612378142655 166.13140190414794 469880.5510683245 0.011849846050167048 0.013635563002800055 5.367883483054308e-07 6.270196919667633 0.22778258297399268 TFTTQETITNAETAK ddPTM_PC-9_Lapatinib_30min_R1 2 TFTTQETITNAETAK 15 0 P06744-2;P06744;A0A2U3TZU2;K7EQ48;A0A0J9YXP8;A0A2R8Y6C7;A0A0J9YYH3;A0A0J9YX90;CON__Q3ZBD7 P06744-2 GPI Glucose-6-phosphate isomerase 0 ; 230.69 3.4837999999999995e-24 28636000.0 50772.0 57053.0 49607.0 50486.0 60501.0 45273.0 55287.0 55063.0 52831.0 55705.0 False True 50047.98196955551 56920.897283825856 45528.50394855761 54198.90885635888 56942.45012954251 43336.779326517615 58149.490338631396 57621.42799736432 46880.61644490657 65333.5350277532 0.7660381754683181 0.8712355340889834 0.6968627050291621 0.8295725745336693 0.8715654235662249 0.6633160031537935 0.890040471771961 0.8819579098679899 0.7175582405726559 1.0 15.995536081878948 -11.040099159885415 2.8243685882624736 1.0085694957063258 0.8020291680235092 0.3651183627210852 0.07952990842636362 32649563.346594177 35135082.555103704 2154670.800681511 0.018769912349257997 9.118026290961668e-12 11.040099159885415 -0.2065403276828166 TFVLTPELS(ph)PGKLQVLPFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TFVLTPELSPGKLQVLPFEK 20 1 Q96DY7 Q96DY7 MTBP Mdm2-binding protein 1 T(0.004)FVLT(0.21)PELS(0.786)PGKLQVLPFEK 64.152 0.0033095 3416200.0 19752.0 12956.0 15049.0 22826.0 22296.0 19242.0 21371.0 21551.0 22484.0 18382.0 True False 23095.623480217382 14242.186056778926 15407.825233650314 21547.133222890487 17927.2588531752 18232.915646394955 19346.584167358775 20985.309085171986 22812.785964451014 21714.511088168078 1.0636032000187126 0.6558833398988793 0.7095635343153461 0.9922918888388516 0.8255888783488892 0.8396650319393931 0.8909518657272669 0.9664186773519656 1.0505779232985526 1.0 14.40637184978929 -7.762667840079992 1.8762235473678535 1.0256600839538348 0.8380486828802776 0.2883384230167678 0.11238712382881512 0.4461842214031986 3.042572733447726 0.08265265962551664 0.03342132785081737 1.727158363412091e-08 7.762667840079992 -0.18761140107355723 TFVNITPAEVGVLVGK ddPTM_PC-9_Lapatinib_30min_R1 2 TFVNITPAEVGVLVGK 16 0 P07737;I3L3D5 P07737 PFN1 Profilin-1 0 ; 176.23 4.7098e-05 171230000.0 581570.0 558500.0 561340.0 543990.0 577560.0 541720.0 610510.0 513940.0 519440.0 565360.0 False True 573276.7051531234 557206.8275641369 515188.7920350613 583996.8392974436 543589.0563266496 518551.89841099776 642119.2205516272 537819.5286302116 460935.1972543062 663081.7227051536 0.8645641789285707 0.8403290401233166 0.7769612317668202 0.8807313175741447 0.8197919467739005 0.7820331652265695 0.9683862464674696 0.8110908658982278 0.6951408574102199 1.0 19.338827163290055 TFWS(ph)PELK ddPTM_PC-9_AZD4547_30min_R2 1 TFWSPELK 8 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EPP6;O15083 X6RM00 ERC1;ERC2 ELKS/Rab6-interacting/CAST family member 1;ERC protein 2 1 T(0.394)FWS(0.606)PELK 106.29 0.0038284 17925000.0 89165.0 80669.0 84671.0 83235.0 102380.0 96248.0 87292.0 104920.0 82047.0 83363.0 True False 117517.61525278604 106743.67668172579 83548.20721695131 64046.45671793082 88166.30420743744 90229.5973448295 95060.81889298881 88707.02482174792 86383.83691772968 80444.48674372246 1.4608535651072023 1.326923459923195 1.0385821402915603 0.7961571924993198 1.0959893931365974 1.1216380512474415 1.1816946411235192 1.102711054697235 1.0738316622359543 1.0 16.295705928900333 -5.130948806206387 3.4745424017050213 1.0547062144559263 1.4371977798330213 0.6679529729647506 0.09841940397517662 0.15729067844686787 3.387988872272188 0.028591576389495242 0.09583935628600732 7.396924634363827e-06 5.130948806206387 0.38249156537709506 TGAAPIIDVVR ddPTM_PC-9_Lapatinib_30min_R1 2 TGAAPIIDVVR 11 0 E9PLL6;P46776;E9PJD9;E9PLX7 E9PLL6 RPL27A 60S ribosomal protein L27a 0 ; 100.48 0.019036 11878500.0 58642.0 54986.0 64298.0 49003.0 60142.0 58418.0 54420.0 54229.0 51700.0 45433.0 False True 57805.75432637426 54858.68329532977 59011.66663745756 52606.84408921591 56604.56580372136 55919.59831900924 57237.601320894944 56748.67731269759 45877.00157486455 53286.033514332856 1.0848199896662545 1.029513357952866 1.1074509162252548 0.9872538941196617 1.062277712761185 1.049423172095705 1.0741576647002482 1.0649822020892838 0.8609573381461124 1.0 15.701469825854781 -8.24307373194279 24.957936248151107 0.9304786695058177 1.0563237877389553 0.575130732303911 0.04365545070501922 447.3355265660111 607907.5514270236 0.027162481113608743 0.0102213293167172 5.713816226519266e-09 8.24307373194279 0.1258451182331376 TGADTTAAGPLFQQRPYPS(ph)PGAVLR ddPTM_PC-9_AZD4547_30min_R2 2 TGADTTAAGPLFQQRPYPSPGAVLR 25 1 H7C053;O60828-5;O60828-4;O60828-2;O60828 H7C053 PQBP1 Polyglutamine-binding protein 1 1 TGADTTAAGPLFQQRPYPS(1)PGAVLR;TGADTTAAGPLFQQRPY(0.012)PS(0.988)PGAVLR 131.64 1.2390000000000002e-07 64455000.0 35169.0 40340.0 48119.0 71699.0 62912.0 58325.0 45282.0 60877.0 52707.0 66161.0 True False 46352.01043935649 53379.116108304595 47480.91061960395 55169.9032885075 54177.754740167 54677.928529810335 49312.01027714247 51469.85846429225 55492.98441652688 63844.72352784117 0.7260116087611137 0.8360771753522784 0.743693573970896 0.8641262776312159 0.848586253436298 0.8564204762507365 0.7723740906425678 0.8061724700216999 0.8691866978220637 1.0 15.962279772307978 -14.522878745279186 0.190242628955141 1.7997088381542445 0.7811543565187425 0.6340628851669843 0.04477288369387412 92.58039345046299 0.9031753444603283 28.02847727037973 0.12316835285360808 3.0000000000079523e-15 14.522878745279186 -1.018554481635502 TGADTTAAGPLFQQRPYPS(ph)PGAVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TGADTTAAGPLFQQRPYPSPGAVLR 25 1 H7C053;O60828-5;O60828-4;O60828-2;O60828 H7C053 PQBP1 Polyglutamine-binding protein 1 1 TGADTTAAGPLFQQRPY(0.002)PS(0.998)PGAVLR;TGADTTAAGPLFQQRPY(0.01)PS(0.99)PGAVLR;TGADTTAAGPLFQQRPY(0.004)PS(0.996)PGAVLR 83.647 7.8556e-06 39738400.0 32570.8 26342.4 28728.8 34676.5 45643.4 41420.9 34986.2 39835.4 29941.7 30098.1 True False 38084.39313737669 28957.499381143345 29413.803546580733 32733.688127729867 36699.90342388846 39248.71508667295 31672.05385784696 38789.76295909518 30379.54071836878 35554.647273571485 1.0711509200004248 0.8144504755829223 0.8272843580829061 0.9206584972103352 1.0322111520754214 1.1038983113706022 0.8907992706030714 1.0909899530329028 0.8544464099057602 1.0 15.117750523370065 -6.112477615788418 5.198063072053063 0.9996243141500364 0.8922209844429074 0.15638963463847633 0.09776848092743962 0.3624004449772797 14.199597593834916 0.028231032070060932 0.03701633715078911 7.718312959426368e-07 6.112477615788418 -0.10740332970712896 TGADTTAAGPLFQQRPYPS(ph)PGAVLR ddPTM_PC-9_Lapatinib_30min_R1 2 TGADTTAAGPLFQQRPYPSPGAVLR 25 1 H7C053;O60828-5;O60828-4;O60828-2;O60828 H7C053 PQBP1 Polyglutamine-binding protein 1 1 TGADTTAAGPLFQQRPY(0.351)PS(0.649)PGAVLR;TGADTTAAGPLFQQRPY(0.027)PS(0.973)PGAVLR 72.822 0.00013401 45776000.0 45987.0 35502.0 41744.0 36706.0 37689.0 37516.0 31606.0 25966.0 44586.0 30845.0 True False 45331.21694701706 35419.797300236365 38311.96945649986 39405.48168762649 35472.20711942494 35911.528134067434 33242.40403065429 27172.475153543433 39564.25516860564 36176.51715162099 1.253056416598298 0.9790825676166365 1.0590286869222065 1.089255815380802 0.9805312924612343 0.9926751097557859 0.9188945384468767 0.7511081025201979 1.0936446701816582 1.0 15.14276590055588 -1.5228787452814863 0.413220761155287 0.9364365083005112 5.548511912928253 0.38238357648887533 0.09697905475826553 81.10883932919779 1.052206246321091 0.06748719939517 307.667094782224 0.029999999999920653 1.5228787452814863 4.612075404627742 TGAIVDVPVGEELLGR ddPTM_PC-9_Lapatinib_30min_R1 2 TGAIVDVPVGEELLGR 16 0 P25705-2;P25705;K7EQH4;K7EJP1;K7ERX7;K7EK77 P25705-2 ATP5A1 ATP synthase subunit alpha, mitochondrial 0 ; 161.87 0.00016235 8292700.0 29699.0 26416.0 36805.0 33246.0 30672.0 27438.0 32446.0 24456.0 38703.0 21686.5 False True 29275.48681387043 26354.835374994203 33779.03497140854 35691.02174540485 28867.93326347217 26264.540701101985 34125.89512050272 25592.3150410174 34343.860579342036 25434.98262955516 1.1509929941863866 1.0361648662724143 1.3280541788991702 1.4032257173210052 1.134969647273435 1.0326148471822776 1.3416913082869109 1.0061856700967202 1.3502608230380648 1.0 14.634526488483107 TGDLGIPPNPEDRS(ph)PS(ph)PEPIYNSEGK ddPTM_PC-9_AZD4547_30min_R2 5 TGDLGIPPNPEDRSPSPEPIYNSEGK 26 1 Q15637-6;Q15637-4;Q15637-7;Q15637-3;Q15637-2;Q15637;Q15637-5 Q15637-6;Q15637-5 SF1 Splicing factor 1 2 T(0.002)GDLGIPPNPEDRS(0.985)PS(0.965)PEPIY(0.033)NS(0.015)EGK;T(0.009)GDLGIPPNPEDRS(0.984)PS(0.928)PEPIY(0.058)NS(0.021)EGK;T(0.019)GDLGIPPNPEDRS(0.988)PS(0.948)PEPIY(0.032)NS(0.013)EGK;T(0.001)GDLGIPPNPEDRS(0.998)PS(0.994)PEPIY(0.005)NS(0.001)EGK;T(0.032)GDLGIPPNPEDRS(0.964)PS(0.96)PEPIY(0.034)NS(0.011)EGK 68.445 0.0011179 18502000.0 103222.5 111517.2 131503.5 139905.0 134212.0 135561.0 121023.0 137463.5 133687.0 134874.6 True False 136045.10783862148 147562.95406229605 129759.67766713952 107652.06376070279 115578.98046775328 127084.34924011328 131793.81254738322 116221.67467198208 140753.42189258034 130152.68130663295 1.0452731858678062 1.133768068247825 0.9969804414665301 0.8271213676119367 0.8880261190736072 0.976425133652907 1.01260927722944 0.8929641211015074 1.0814484994048843 1.0 16.98984550779187 -5.484576167247976 7.474811019374253 0.9473594562775078 1.0844597775201879 0.3578712432425357 0.07125503821622907 0.25632239434558973 42.589202349982024 0.019010587941071563 0.038824550766374505 3.276603061868272e-06 5.484576167247976 0.13710032124268 TGDLGIPPNPEDRS(ph)PS(ph)PEPIYNSEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TGDLGIPPNPEDRSPSPEPIYNSEGK 26 1 Q15637-6;Q15637-4;Q15637-7;Q15637-3;Q15637-2;Q15637;Q15637-5 Q15637-6;Q15637-5 SF1 Splicing factor 1 2 T(0.001)GDLGIPPNPEDRS(0.986)PS(0.968)PEPIY(0.032)NS(0.013)EGK;T(0.005)GDLGIPPNPEDRS(0.998)PS(0.957)PEPIY(0.003)NS(0.036)EGK;T(0.078)GDLGIPPNPEDRS(0.915)PS(0.96)PEPIY(0.036)NS(0.011)EGK;T(0.004)GDLGIPPNPEDRS(0.981)PS(0.973)PEPIY(0.018)NS(0.024)EGK 72.707 0.0031796999999999997 6802000.0 33677.5 41013.0 33313.6 41460.700000000004 40834.1 34148.200000000004 43294.3 40643.7 33975.8 31902.8 True False 39378.435589055305 45084.49959452567 34107.92256653156 39137.79139640301 32832.95123503954 32357.40827752957 39193.15048041179 39576.84594055982 34472.631799101364 37686.52509757417 1.0448943086978861 1.1963029087398587 0.9050429159553115 1.038508891309861 0.8712119557330307 0.8585935740626924 1.0399778270598525 1.0501590644956365 0.9147203598593471 1.0 15.20176115636086 -5.265863320360075 24.99907806552155 0.9604676802572977 1.1205986106256334 0.42063820681165653 0.07549276567916037 327.7153576282662 1851884.6925095606 0.020023809117845116 0.044071147326257186 5.42171493870066e-06 5.265863320360075 0.1601309303683357 TGDLGIPPNPEDRS(ph)PS(ph)PEPIYNSEGK ddPTM_PC-9_Lapatinib_30min_R1 4 TGDLGIPPNPEDRSPSPEPIYNSEGK 26 1 Q15637-6;Q15637-4;Q15637-7;Q15637-3;Q15637-2;Q15637;Q15637-5 Q15637-6;Q15637-5 SF1 Splicing factor 1 2 T(0.002)GDLGIPPNPEDRS(0.987)PS(0.955)PEPIY(0.035)NS(0.022)EGK;T(0.003)GDLGIPPNPEDRS(0.995)PS(0.963)PEPIY(0.031)NS(0.009)EGK;T(0.002)GDLGIPPNPEDRS(0.995)PS(0.992)PEPIY(0.006)NS(0.005)EGK;T(0.037)GDLGIPPNPEDRS(0.964)PS(0.971)PEPIY(0.013)NS(0.016)EGK 63.412 0.0028428 16621700.0 58821.0 61749.0 65140.0 62311.7 80101.0 64114.0 63911.3 62645.1 65221.0 61409.1 True False 57982.201753549714 61606.023984347274 59784.44064767157 66894.31028373765 75389.6166646251 61371.99367703378 67220.31439360733 65555.82004318108 57875.12417242247 72023.58111251768 0.8050446931119399 0.8553590786898565 0.830067593477118 0.9287834518979705 1.0467351872832993 0.8521097219694806 0.9333098043069182 0.9101993962334024 0.8035579914029543 1.0 16.136181713662847 -5.760453356942707 24.91938495059615 0.9236017051716205 0.832677297263303 0.30913480491801826 0.06488891005111654 32.59326937931244 823663.4029866842 0.018040756557727612 0.02909444607058504 1.7359876972586772e-06 5.760453356942707 -0.09092440790831757 TGDLGIPPNPEDRSPS(ph)PEPIYNSEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGDLGIPPNPEDRSPSPEPIYNSEGK 26 1 Q15637-6;Q15637-4;Q15637-7;Q15637-3;Q15637-2;Q15637;Q15637-5 Q15637-6;Q15637-5 SF1 Splicing factor 1 1 T(0.001)GDLGIPPNPEDRS(0.052)PS(0.607)PEPIY(0.142)NS(0.198)EGK 55.406000000000006 0.022655 0.0 5752.8 4327.1 9602.9 8532.6 11461.0 14216.0 9480.3 7709.5 10939.0 8915.5 True False 6726.635417020787 4756.665891192351 9831.869555201054 8054.546085062439 9215.299323476896 13470.487934162278 8582.257352571765 7507.133793890462 11098.962180445193 10531.809574940833 0.6386970224970647 0.4516475404673346 0.933540384037592 0.7647827306170876 0.8749967665009427 1.279028816302725 0.8148891500082007 0.7128056902730922 1.0538513919634316 1.0 13.362465720993637 -5.269064756623491 24.58004283652723 0.9195781557565003 0.5451722753156149 0.4837640645393886 0.15844691159591304 359.7068028131098 1159501.6781015529 0.042571116590061124 0.09146367348815534 5.381895283649304e-06 5.269064756623491 -0.3744058804408854 TGEDEDEEDNDALLKENES(ph)PDVRR ddPTM_PC-9_Lapatinib_30min_R1 2 TGEDEDEEDNDALLKENESPDVRR 24 2 A0A087WWS1;Q96FV9 A0A087WWS1 THOC1 THO complex subunit 1 1 TGEDEDEEDNDALLKENES(1)PDVRR;TGEDEDEEDNDALLKENES(1)PDVRR 91.06700000000001 3.7466000000000003e-06 10500100.0 42842.0 52576.0 42173.0 43360.0 49330.0 47005.0 51128.0 47989.0 49511.0 39085.0 True False 42231.06522373941 52454.26350225978 38705.698732487755 46548.83904471979 46428.50638651153 44994.70572400678 53775.15766877466 50218.74413245762 43934.54980605648 45840.79017251116 0.9212551761174407 1.144270491517715 0.844350601000285 1.0154458260763841 1.0128208133365206 0.9815429785280678 1.1730853125874217 1.0955034575859415 0.9584160665799829 1.0 15.484344292059149 TGGLYSCDITAR ddPTM_PC-9_AZD4547_30min_R2 1 TGGLYSCDITAR 12 0 P23229-4;P23229-2;P23229-5;P23229-3;P23229-9;P23229-6;P23229 P23229-4 ITGA6 Integrin alpha-6;Integrin alpha-6 heavy chain;Integrin alpha-6 light chain;Processed integrin alpha-6 0 68.069 0.029702999999999997 180310.0 1174.9 623.28 1207.7 3865.0 2116.5 2295.4 2145.8 3443.7 2036.5 2806.9 False True 1548.4937605618586 824.7430710952921 1191.6851089028378 2973.983963654743 1822.6605084493178 2151.8682751363326 2336.77204303459 2911.5552933535373 2144.145232402849 2708.631285353869 0.5716886491472226 0.3044870210112572 0.4399584082730368 1.097965596032096 0.6729083128829019 0.7944485787976867 0.8627132292497695 1.0749175456611317 0.7915973074654669 1.0 11.403348303526707 -5.742810454217615 24.909102083693746 0.8870266098224798 0.42528858976610273 0.6969953403788789 0.13889481886064337 126.54257411647149 169201.178185074 0.03716051210222188 0.06421570993381266 1.80796303079615e-06 5.742810454217615 -0.4617380200563771 TGGPAYGPSSDVSTAS(ph)ETESEKR ddPTM_PC-9_Lapatinib_30min_R1 2 TGGPAYGPSSDVSTASETESEKR 23 1 P51116 P51116 FXR2 Fragile X mental retardation syndrome-related protein 2 1 TGGPAYGPSSDVS(0.067)T(0.258)AS(0.666)ET(0.006)ES(0.003)EKR;TGGPAYGPSS(0.003)DVS(0.002)T(0.015)AS(0.958)ET(0.015)ES(0.006)EKR 82.541 4.353e-05 16855900.0 62863.0 63379.0 61339.0 49351.0 59861.0 64103.0 59339.0 64291.0 57506.0 52383.0 True False 61966.56209233771 63232.24981949417 56295.94419538728 52980.43717010993 56340.09367125413 61361.46412139152 62411.28307204311 67278.19456583455 51029.06871497409 61437.331754039966 1.0086141491368226 1.0292154300033738 0.9163149275551896 0.8623492534183187 0.917033537472098 0.9987651216209685 1.0158527606944632 1.0950702552509615 0.8305873197629314 1.0 15.90682794019177 -6.780578406698132 24.26650876659808 0.9957343628171405 0.9449145291192431 0.06485613326688222 0.07559754931498698 461.47621824415046 585103.7387905609 0.027515199323009186 0.024308691684113 1.6573780899550492e-07 6.780578406698132 -0.05081983369789733 TGGPAYGPSSDVSTAS(ph)ETESEKREEPNR ddPTM_PC-9_Lapatinib_30min_R1 1 TGGPAYGPSSDVSTASETESEKREEPNR 28 2 P51116 P51116 FXR2 Fragile X mental retardation syndrome-related protein 2 1 TGGPAY(0.002)GPS(0.086)S(0.086)DVS(0.18)T(0.18)AS(0.452)ET(0.011)ES(0.003)EKREEPNR 54.943000000000005 0.009417299999999998 4805000.0 8513.9 7612.1 7028.2 10942.0 9294.0 7923.6 6024.0 7168.4 7251.9 5313.1 True False 8392.490224741956 7594.474650136028 6450.368525636556 11746.71118144197 8747.345192707036 7584.726098813744 6335.893244341625 7501.470033530796 6435.114656107552 6231.462255739258 1.346793076859667 1.2187307470475999 1.0351291977570245 1.8850649653896396 1.4037387749000032 1.217166338739854 1.0167586650318206 1.2038057402372686 1.0326813181257302 1.0 12.605355026012381 -6.971981413144731 3.8443484999888367 1.0822274054091157 1.3765128390898589 0.3362359624271336 0.20752694048819434 0.3027141043839147 9.782967639386818 0.08310750427918805 0.06975234680527297 1.0666417701914901e-07 6.971981413144731 0.2942854336807432 TGISDVFAK ddPTM_PC-9_Lapatinib_30min_R1 2 TGISDVFAK 9 0 P19338 P19338 NCL Nucleolin 0 ; 135.79 0.004784399999999999 27161000.0 114105.0 91994.0 120670.0 113996.0 116242.0 90792.0 121808.0 98297.0 100479.0 96560.0 False True 112477.84177570592 91780.99354509442 110748.97839967055 122379.64611950816 109404.87410056502 86909.03780648927 128114.62222887854 102864.2374708408 89161.99692922276 113250.26734188761 0.9931794813000323 0.810426285953213 0.977913615562019 1.0806124258414347 0.9660451729467989 0.7674069107856705 1.1312522719449076 0.9082913434571174 0.7873005426120052 1.0 16.789154930380377 TGKEYIPGQPPLSQSSDS(ph)SPTR ddPTM_PC-9_AZD4547_30min_R2 1 TGKEYIPGQPPLSQSSDSSPTR 22 1 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 TGKEYIPGQPPLS(0.014)QS(0.039)S(0.039)DS(0.484)S(0.341)PT(0.083)R 80.171 0.00024529 4529100.0 24661.0 4813.3 26017.0 205760.0 102630.0 25638.0 13788.0 24710.0 9898.9 35920.0 True False 32502.685019334367 6369.105095788364 25671.997580794177 158325.21096031056 88381.5960227513 24034.85180706863 15015.10528910472 20891.637279311744 10422.135644995122 34662.4517331971 0.9376914613401605 0.1837465262068728 0.740628440780704 4.567628746488193 2.5497791299657555 0.6933973393477487 0.433180705296861 0.6027166641332327 0.3006750856868437 1.0 15.081086081890275 -6.874336443923768 7.689457606674608 0.5545679420945796 1.7991437521160283 0.2143124858646963 1.1394719788896828 0.4258736858247956 27.12993906702881 0.45486599594165816 0.40136146293471775 1.3355604693177702e-07 6.874336443923768 1.2445758100214488 TGKEYIPGQPPLSQSSDS(ph)SPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TGKEYIPGQPPLSQSSDSSPTR 22 1 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 TGKEYIPGQPPLS(0.006)QS(0.015)S(0.015)DS(0.405)S(0.405)PT(0.155)R;TGKEYIPGQPPLS(0.005)QS(0.013)S(0.013)DS(0.496)S(0.344)PT(0.128)R 89.345 9.850600000000001e-05 9532100.0 26352.5 5102.9 13107.8 51218.0 39516.0 141123.0 32102.0 123956.0 98147.0 50080.0 True False 30813.45776439998 5609.482188108769 13420.339663608325 48348.42151099645 31773.123467979512 133722.2614471568 29061.066161646664 120702.2863422385 99582.21419911807 59159.107566938095 0.520857379897673 0.09482026384122988 0.22685162463655 0.8172608326839712 0.537079154414702 2.2603833449625834 0.49123570920613163 2.0402993098850377 1.6832947333838923 1.0 15.852312668658778 -6.6314791419440215 8.345272119811764 1.4956951915701133 0.4159763481223132 0.5296505221210956 0.49834858694368883 0.1967075919873681 13.883855980678037 0.159706066231547 0.15957304677643783 2.3362583040505258e-07 6.6314791419440215 -1.0797188434478002 TGKEYIPGQPPLSQSSDS(ph)SPTR ddPTM_PC-9_Lapatinib_30min_R1 2 TGKEYIPGQPPLSQSSDSSPTR 22 1 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 TGKEYIPGQPPLS(0.066)QS(0.113)S(0.113)DS(0.314)S(0.314)PT(0.078)R;TGKEYIPGQPPLS(0.003)QS(0.023)S(0.023)DS(0.404)S(0.404)PT(0.141)R 93.39200000000001 8.9016e-05 7543200.0 269346.0 14836.4 39432.9 19073.8 15529.6 21349.3 12773.5 12103.7 23888.8 11179.099999999999 True False 265505.0766479932 14802.047227345696 36190.8791773959 20476.55088033156 14616.179460368325 20436.24020664904 13434.849328784496 12666.082088729234 21198.19178378384 13111.392539785586 20.249952538781596 1.128945471080203 2.7602620444454895 1.5617373073223861 1.114769420259257 1.5586628304077332 1.024669903522254 0.9660363725893273 1.6167765338013822 1.0 13.678533299552463 -4.76085876378054 24.999999185687017 1.4431775025009757 20.249973985271478 0.9919285248150164 0.5097122939813243 1.1257051211332547 48429.53813923994 0.13154110801078434 0.7582541697930643 1.7343679370955403e-05 4.76085876378054 18.8067964827705 TGNESGSNLS(ph)DSGSVK ddPTM_PC-9_Lapatinib_30min_R1 1 TGNESGSNLSDSGSVK 16 0 Q9UDT6-2;Q9UDT6 Q9UDT6-2 CLIP2 CAP-Gly domain-containing linker protein 2 1 TGNESGS(0.011)NLS(0.883)DS(0.059)GS(0.047)VK 131.25 7.5427e-05 0.0 20396.0 19101.0 26535.0 14088.0 23849.0 24855.0 17880.0 24046.0 28755.0 16552.0 True False 20105.14929983168 19056.77280806195 24353.3947280621 15124.078516190315 22446.24870893803 23792.009589834877 18805.73891248809 25163.26494423881 25516.30909642612 19412.991145846336 1.0356543795227269 0.9816505176812691 1.2544895603721957 0.7790699744601857 1.1562488511071463 1.22557154696511 0.9687192855137022 1.2962075115159584 1.3143934855132138 1.0 14.244734804598002 -6.483164590274877 24.99420866945531 1.170079206919328 1.020253249620022 0.1871165291660437 0.14968316599269021 897.5691818141211 564887.6652225896 0.04560191977142011 0.05170043155476458 3.28727025274273e-07 6.483164590274877 -0.14982595729930592 TGNESGSNLSDS(ph)GSVK ddPTM_PC-9_AZD4547_30min_R2 1 TGNESGSNLSDSGSVK 16 0 Q9UDT6-2;Q9UDT6 Q9UDT6-2 CLIP2 CAP-Gly domain-containing linker protein 2 1 TGNESGS(0.001)NLS(0.334)DS(0.643)GS(0.022)VK 128.44 2.097e-05 5960500.0 13205.0 12341.0 27676.0 33149.0 29293.0 27882.0 17282.0 30134.0 19463.0 22808.0 True False 17403.915318937212 16329.98690859164 27308.998156822847 25507.010196944655 25226.172583985768 26138.534132330424 18820.06452032983 25477.482710432236 20491.774445498 22009.49886221489 0.7907456425014576 0.7419517823109717 1.2407823698206026 1.1589091762890689 1.1461493395150921 1.1876024209349043 0.8550882797535857 1.157567597060152 0.9310423001351265 1.0 14.425838676199717 -5.247197020178292 24.96565758464374 1.0905979018539744 0.766348650406363 0.5460457160633472 0.11598438663905031 569.8991308468967 998981.2109607124 0.029522645690285787 0.07727862967198566 5.659824696009562e-06 5.247197020178292 -0.3242492514476114 TGNESGSNLSDS(ph)GSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGNESGSNLSDSGSVK 16 0 Q9UDT6-2;Q9UDT6 Q9UDT6-2 CLIP2 CAP-Gly domain-containing linker protein 2 1 TGNESGSNLS(0.069)DS(0.466)GS(0.466)VK 145.82 4.8068e-10 0.0 9740.3 8460.1 12415.0 11781.0 17022.0 15319.0 12207.0 15292.0 14247.0 8790.6 True False 11389.140410305863 9299.962817146912 12711.020684149698 11120.948764517336 13686.661293449419 14515.644672441744 11050.664588973304 14890.601203213308 14455.335422324053 10384.266193648684 1.0967689192397427 0.8955820896458757 1.224065374202765 1.0709421886083033 1.3180191106638401 1.3978498241233386 1.0641738552245712 1.433957963473705 1.3920420714142856 1.0 13.342111650985904 -5.783827110862311 1.32333205685484 1.2825014767646985 1.0073932800811094 0.2657196953150822 0.15390008197653385 0.5523792787693368 1.9332146902199299 0.05142887071467699 0.12367107729091485 1.6450264646777036e-06 5.783827110862311 -0.2751081966835891 TGNESGSNLSDS(ph)GSVK ddPTM_PC-9_Lapatinib_30min_R1 1 TGNESGSNLSDSGSVK 16 0 Q9UDT6-2;Q9UDT6 Q9UDT6-2 CLIP2 CAP-Gly domain-containing linker protein 2 1 TGNESGSNLS(0.169)DS(0.81)GS(0.021)VK 166.9 4.8355e-21 0.0 23850.0 18662.0 36287.0 21091.0 30607.0 35671.0 27687.0 25260.0 30744.0 18854.0 True False 23509.89462644566 18618.789285589854 33303.62293187071 22642.102497513493 28806.756435677253 34145.434483162346 29120.497386468553 26433.671816163707 27281.286971327576 22112.888778624147 1.0631760898273932 0.8419881034986287 1.5060729181645551 1.0239323647031102 1.3027133959776374 1.5441417367490082 1.3169015445244967 1.1953965888760916 1.2337278609070543 1.0 14.43259988748779 -6.280750584871296 23.476074152269888 1.2917541923830658 1.118112106429909 0.1195536685565799 0.20021742682848367 748.6547948262976 910114.5436228414 0.06274528839468395 0.07128715396736965 5.239012264481701e-07 6.280750584871296 -0.17364208595315667 TGPLSTSSPS(ph)RR ddPTM_PC-9_AZD4547_30min_R2 1 TGPLSTSSPSRR 12 1 Q8IY92;Q8IY92-2 Q8IY92 SLX4 Structure-specific endonuclease subunit SLX4 1 TGPLS(0.005)T(0.03)S(0.28)S(0.28)PS(0.405)RR 59.418 0.029432 4937700.0 24721.0 23149.0 30843.0 40318.0 44649.0 28876.0 27492.0 34492.0 24605.0 30967.0 True False 32581.763771256847 30631.461546632203 30434.001667541794 31023.308006890544 38450.2570478401 27070.379155195944 29938.734740939006 29162.053947309636 25905.570067896933 29882.854755621236 1.0903163047073983 1.0250513813734663 1.018443582998605 1.0381641332662428 1.286699592869629 0.9058833025350016 1.0018699681062853 0.9758791181697254 0.8669041254508612 1.0 14.867030357162747 TGQAGSLSGS(ph)PKPFSPQLSAPITTK ddPTM_PC-9_AZD4547_30min_R2 2 TGQAGSLSGSPKPFSPQLSAPITTK 25 1 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;A0A087WYS3;Q9ULU4-4;Q9ULU4-8;Q9ULU4-17;A0A087WV57 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 T(0.015)GQAGS(0.092)LS(0.214)GS(0.67)PKPFS(0.008)PQLSAPITTK;T(0.002)GQAGS(0.017)LS(0.13)GS(0.743)PKPFS(0.046)PQLS(0.059)APIT(0.002)T(0.001)K 66.613 0.00036027 251660000.0 105003.0 89789.0 104387.0 125181.0 124433.0 111606.0 112569.0 101500.0 106793.0 122437.0 True False 138391.76980192057 118811.53833040557 103002.7601747459 96322.45447717054 107157.62581992647 104627.25917699131 122587.42292495108 85815.50723796603 112437.85995776934 118150.51789692215 1.171317504699027 1.0055947315784102 0.8717927099110003 0.8152520716092415 0.9069585790001684 0.8855421122086921 1.0375529883999308 0.7263235808482355 0.951649319521928 1.0 16.850266427622323 -4.890527110607843 2.5207315946570494 0.8917622114943224 1.198443228903402 0.4963416957665424 0.08424504598327277 0.31120990365735784 3.0437851370657154 0.02122213763927193 0.18773626204497365 1.2866869297582087e-05 4.890527110607843 0.3066810174090795 TGQAGSLSGS(ph)PKPFSPQLSAPITTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TGQAGSLSGSPKPFSPQLSAPITTK 25 1 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;A0A087WYS3;Q9ULU4-4;Q9ULU4-8;Q9ULU4-17;A0A087WV57 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 T(0.002)GQAGS(0.048)LS(0.125)GS(0.814)PKPFS(0.01)PQLS(0.001)APITTK;T(0.004)GQAGS(0.055)LS(0.112)GS(0.789)PKPFS(0.026)PQLS(0.012)APIT(0.001)TK 61.091 0.0013122 224770000.0 95234.8 103849.0 81597.4 127782.0 122363.0 111698.0 135383.0 101899.0 104928.9 110182.0 True False 111356.17066696037 114158.4424058688 83542.99147586286 120622.78881483333 98386.84854014506 105840.36024690911 122558.54215195989 99224.25922091519 106463.28665652394 130157.12439976822 0.8555518661040631 0.8770817804428391 0.6418626092204265 0.9267474936243146 0.7559082838827704 0.8131737754272143 0.9416199283531355 0.7623421282430537 0.8179597324963145 1.0 16.989894757019464 -7.04447926132214 24.979124953500747 0.8630643834987518 0.8093114306171685 0.10254305750718529 0.09408239468312984 1335.826080249038 750182.9528038321 0.03487233636853343 0.027013508538579836 9.026528104337859e-08 7.04447926132214 -0.05375295288158333 TGQAGSLSGS(ph)PKPFSPQLSAPITTK ddPTM_PC-9_Lapatinib_30min_R1 1 TGQAGSLSGSPKPFSPQLSAPITTK 25 1 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;A0A087WYS3;Q9ULU4-4;Q9ULU4-8;Q9ULU4-17;A0A087WV57 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 T(0.002)GQAGS(0.161)LS(0.215)GS(0.62)PKPFS(0.002)PQLSAPITTK 67.47800000000001 0.00032878 111350000.0 17333.0 11112.0 12324.0 11633.0 11829.0 13219.0 9984.5 13224.0 12156.0 10585.0 True False 17085.828241517087 11086.270846719239 11310.768292015722 12488.529626550397 11133.24147670879 12653.654184994053 10501.4485554663 13838.435316585466 10786.863271645143 12414.603146374073 1.3762685798383605 0.8930024355999814 0.9110857720264101 1.0059548001095722 0.8967859339072366 1.0192556327255455 0.8458948249613161 1.1146901075631444 0.8688850657941214 1.0 13.599750523632945 -4.756587336671872 24.99992611143796 0.9518853254275502 1.3762692261732878 0.7226600271898895 0.07910341140901575 72.86933351113909 375412.2482844974 0.01798300943774784 0.14364220948673836 1.7515101698864415e-05 4.756587336671872 0.4243839007457376 TGQAGSLSGSPKPFSPQLS(ph)APITTK ddPTM_PC-9_Lapatinib_30min_R1 1 TGQAGSLSGSPKPFSPQLSAPITTK 25 1 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;A0A087WYS3;Q9ULU4-4;Q9ULU4-8;Q9ULU4-17;A0A087WV57 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 TGQAGSLSGSPKPFS(0.119)PQLS(0.851)APIT(0.022)T(0.007)K 57.802 0.0022558000000000005 3329700.0 8012.9 6428.8 7081.3 7659.8 7947.5 7897.9 7813.8 5453.3 5840.8 4999.1 True False 7898.634576614107 6413.914508584295 6499.102848608484 8223.127244343736 7480.0436753861795 7560.125227904123 8218.36033078297 5706.680226250419 5182.947597649303 5863.18777411796 1.3471570212165607 1.0939295747779774 1.1084589303616819 1.4025010900458152 1.2757639638296345 1.2894223277782444 1.4016880658438944 0.9733067481552584 0.8839811715614054 1.0 12.517469545805618 -7.837928305530151 7.301490418593492 0.9409591734951797 1.2660557448367304 0.6717130029904008 0.10296721645970972 0.14617079940464583 11.693222440918165 0.05977366812558454 0.02858593336670797 1.4523513557622689e-08 7.837928305530151 0.3250965713415508 TGQATVASGIPAGWMGLDCGPESSKK ddPTM_PC-9_Lapatinib_30min_R1 1 TGQATVASGIPAGWMGLDCGPESSKK 26 1 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 107.75 4.3168e-10 2676400.0 6142.0 7526.4 10649.0 4989.4 7217.1 5249.9 6965.9 6606.0 7379.5 7960.2 False True 6054.413953695147 7508.973083220636 9773.480326328747 5356.33712015048 6792.604367364534 5025.374015114633 7326.560217589531 6912.938876388656 6548.34300041998 9336.109963700219 0.6484942847969173 0.804293556140225 1.0468471734297335 0.573722582636289 0.7275625923189526 0.5382727961274897 0.7847551331417443 0.7404517409570894 0.701399514988644 1.0 13.188605838332744 -11.008831069540983 5.3485297517419825 1.000475913263558 0.7327442264224338 0.2699933652710821 0.13332626201314018 0.0007748061597471682 7.446650360242951e-05 0.13219490450554985 0.03200608776578712 9.798710583558826e-12 11.008831069540983 -0.26773168684112414 TGQLEGAPAPGPAAS(ph)PQTLDHSGATATGGASELK ddPTM_PC-9_AZD4547_30min_R2 3 TGQLEGAPAPGPAASPQTLDHSGATATGGASELK 34 0 P55317-2;P55317 P55317-2 FOXA1 Hepatocyte nuclear factor 3-alpha 1 TGQLEGAPAPGPAAS(0.783)PQT(0.215)LDHS(0.001)GATATGGASELK;TGQLEGAPAPGPAAS(0.929)PQT(0.068)LDHS(0.003)GATATGGASELK;TGQLEGAPAPGPAAS(0.491)PQT(0.491)LDHS(0.016)GAT(0.002)AT(0.001)GGASELK 91.223 2.7576e-12 126303500.0 191824.0 194417.0 270300.0 309423.0 274982.0 305590.0 269792.0 307892.0 256912.0 273204.0 True False 252820.04181293477 257258.49321835014 266715.6453891177 238090.3078876948 236805.49583482678 286481.4089914223 293802.9653436422 260314.36605430458 270491.84382375685 263639.2111168252 0.9589622148463487 0.9757975383424753 1.011669107411072 0.9030914137510107 0.8982180413591524 1.0866418837237195 1.114413004420085 0.987388654940834 1.0259924640113383 1.0 18.00820543308616 -6.766458651338744 24.99999755036975 1.0465693563290916 0.9518762771559812 0.49914727207631227 0.046647449173158155 116.33480879984016 579436.4284575037 0.01749379601128751 0.015902040057987513 1.7121481805356005e-07 6.766458651338744 -0.09469307917311043 TGQLEGAPAPGPAAS(ph)PQTLDHSGATATGGASELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGQLEGAPAPGPAASPQTLDHSGATATGGASELK 34 0 P55317-2;P55317 P55317-2 FOXA1 Hepatocyte nuclear factor 3-alpha 1 TGQLEGAPAPGPAAS(0.944)PQT(0.033)LDHS(0.016)GAT(0.006)AT(0.002)GGASELK 122.81 1.6583e-24 49510000.0 58007.0 63606.0 52498.0 70096.0 74944.0 56535.0 71857.0 49025.0 52257.0 44222.0 True False 67826.43940952656 69920.38332259035 53749.75141977369 66168.74837429832 60259.261190005505 53570.205075820544 65050.18476037155 47738.145696281186 53021.159764468845 52239.0985388406 1.2983845683917483 1.3384684130910767 1.0289180503336959 1.2666518034399235 1.1535279680448887 1.0254810395702032 1.245239419895535 0.9138393852793444 1.014970802473683 1.0 15.672842380860182 -2.6994165461134734 0.20226448435860978 0.9545388098208732 2.14487764815842 0.48507957836721116 0.10206233440434208 28.152269505672663 0.5169434399690771 0.18974602929125578 9.666825751958415 0.00199794465595357 2.6994165461134734 1.1903388383375466 TGQLEGAPAPGPAAS(ph)PQTLDHSGATATGGASELK ddPTM_PC-9_Lapatinib_30min_R1 4 TGQLEGAPAPGPAASPQTLDHSGATATGGASELK 34 0 P55317-2;P55317 P55317-2 FOXA1 Hepatocyte nuclear factor 3-alpha 1 TGQLEGAPAPGPAAS(0.786)PQT(0.182)LDHS(0.025)GAT(0.004)AT(0.002)GGASELK;T(0.001)GQLEGAPAPGPAAS(0.592)PQT(0.392)LDHS(0.011)GAT(0.002)AT(0.002)GGASELK;TGQLEGAPAPGPAAS(0.985)PQT(0.014)LDHSGATATGGASELK;TGQLEGAPAPGPAAS(0.787)PQT(0.181)LDHS(0.028)GAT(0.004)ATGGASELK 136.63 1.202e-21 125771400.0 134270.0 181363.0 218950.0 205677.0 231310.0 233112.0 208045.0 236681.0 236558.0 189876.0 True False 132355.28517789743 180943.06511640945 200948.77617144168 220803.17269835816 217704.80057295744 223142.3431706132 218816.552127997 247678.06330647075 209914.34697382618 222695.81360613368 0.5943321656328253 0.8125121985293834 0.9023464470097563 0.9915012281680207 0.9775882045003167 1.0020051098278355 0.9825804472238636 1.112181047752076 0.9426057166260288 1.0 17.76471491201272 -4.320355395527263 0.812740791058834 1.0127540498363818 1.827616133454003e-11 0.9030907575457372 0.04170235334512019 1.2582876486742849 0.37988674530168115 0.014532864820686118 1.3683215042593473 4.782385759206757e-05 4.320355395527263 -1.0127540498181056 TGQLEGAPAPGPAASPQT(ph)LDHSGATATGGASELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TGQLEGAPAPGPAASPQTLDHSGATATGGASELK 34 0 P55317-2;P55317 P55317-2 FOXA1 Hepatocyte nuclear factor 3-alpha 1 TGQLEGAPAPGPAAS(0.195)PQT(0.804)LDHS(0.001)GATATGGASELK;TGQLEGAPAPGPAAS(0.034)PQT(0.958)LDHS(0.007)GAT(0.001)ATGGASELK;TGQLEGAPAPGPAAS(0.006)PQT(0.972)LDHS(0.013)GAT(0.006)AT(0.002)GGASELK 128.65 7.5394e-22 83714000.0 196525.0 254962.0 223183.0 266304.0 303295.0 234641.0 240154.0 201956.0 212503.0 200405.0 True False 229792.80095431965 280272.94237484346 228504.52914624105 251383.85024921657 243866.52197137443 222336.01289812668 217404.8745556074 196654.86899006923 215610.45435882095 236736.84009489242 0.9706676867960671 1.1839008337802441 0.9652258983208885 1.0618704302568756 1.0301164866170562 0.9391694710844607 0.9183398514082722 0.83068976045825 0.9107600417087459 1.0 17.852924704744943 -6.825401356564436 2.2536794075663877 0.9012638200124304 1.0506688089937708 0.4443974923907429 0.06833241380501015 0.2494247331944901 2.595928138944469 0.026019669685875213 0.023031139009965375 1.4948535372244798e-07 6.825401356564436 0.14940498898134036 TGQPAQPAPSAQQPPRPPAS(ph)PDEPSVAASSVGSSR ddPTM_PC-9_AZD4547_30min_R2 2 TGQPAQPAPSAQQPPRPPASPDEPSVAASSVGSSR 35 1 O94964-2 O94964-2 SOGA1 Protein SOGA1;N-terminal form;C-terminal 80 kDa form 1 TGQPAQPAPS(0.026)AQQPPRPPAS(0.572)PDEPS(0.323)VAAS(0.031)S(0.038)VGS(0.005)S(0.005)R;TGQPAQPAPS(0.024)AQQPPRPPAS(0.868)PDEPS(0.082)VAAS(0.024)S(0.002)VGSSR 61.181000000000004 0.00012201 112552000.0 24384.1 24887.1 36239.0 52515.0 37716.8 41007.0 30689.0 42968.0 28047.1 37425.5 True False 32137.73657921217 32931.368381234184 35758.44718185806 40408.478098662046 32480.47335935801 38442.82580749134 33420.26154752935 36328.282906413086 29529.612446710526 36115.24463643563 0.8898662296970663 0.9118412103461339 0.9901205859694604 1.1188759346764912 0.899356315770028 1.0644487167257752 0.9253782407945428 1.0058988461000906 0.8176495201397294 1.0 15.140320322448998 -10.289256606135563 12.249845899601674 0.9999923722073181 0.9643007869754249 0.016912821117407772 0.08476555799646339 0.0 0.0 0.08027040825720007 0.019468433638581646 5.137400147667013e-11 10.289256606135563 -0.0356915852318932 TGQPAQPAPSAQQPPRPPAS(ph)PDEPSVAASSVGSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TGQPAQPAPSAQQPPRPPASPDEPSVAASSVGSSR 35 1 O94964-2 O94964-2 SOGA1 Protein SOGA1;N-terminal form;C-terminal 80 kDa form 1 TGQPAQPAPS(0.034)AQQPPRPPAS(0.71)PDEPS(0.088)VAAS(0.066)S(0.035)VGS(0.032)S(0.035)R;TGQPAQPAPS(0.025)AQQPPRPPAS(0.831)PDEPS(0.078)VAAS(0.045)S(0.013)VGS(0.004)S(0.004)R 50.733000000000004 0.0022095 57885000.0 30404.0 32042.2 42847.0 50713.0 47418.0 48831.0 56961.0 46239.0 36019.8 38046.7 True False 35550.796693627424 35223.137856477435 43868.6349781524 47871.715023764315 38126.78329296113 46270.216397937395 51565.24171807227 45025.27524427018 36546.52143223329 44944.26553248854 0.7909973891536635 0.7837070522604477 0.9760674572919962 1.0651351058158827 0.8483125231048819 1.0295021144463996 1.147315260515219 1.001802448228308 0.8131520450771449 1.0 15.455849432650623 -5.276371102728451 5.796474801254344 0.9911729628225 0.7858765503831538 0.4270794964394192 0.09151545250087464 0.14301226111702758 18.96568022981092 0.0247641102840668 0.05711273672214964 5.292110421190017e-06 5.276371102728451 -0.20529641243934615 TGQPAQPAPSAQQPPRPPAS(ph)PDEPSVAASSVGSSR ddPTM_PC-9_Lapatinib_30min_R1 2 TGQPAQPAPSAQQPPRPPASPDEPSVAASSVGSSR 35 1 O94964-2 O94964-2 SOGA1 Protein SOGA1;N-terminal form;C-terminal 80 kDa form 1 TGQPAQPAPS(0.019)AQQPPRPPAS(0.935)PDEPS(0.027)VAAS(0.008)S(0.009)VGS(0.001)S(0.001)R;TGQPAQPAPS(0.005)AQQPPRPPAS(0.96)PDEPS(0.026)VAAS(0.006)S(0.003)VGSSR 77.119 1.4749e-08 123501000.0 83844.0 80172.0 81540.0 74991.0 95221.0 95291.0 73031.0 63030.0 94606.0 67338.0 True False 82648.3691848935 79986.36665975286 74836.09595350231 80506.08830264246 89620.28799168879 91215.62606417037 76812.18783657259 65958.60390232768 83950.47603465454 78977.28357775515 1.0464828041790533 1.0127768775562438 0.9475648257745439 1.0193575247923303 1.1347603251440692 1.154960286452069 0.9725858418636167 0.8351591864689769 1.0629699102274537 1.0 16.269150126731134 -7.500991259377707 24.520149069752808 0.9502132317206293 1.049571408248598 0.2177091854584472 0.07712054847368506 862.3549622230724 966084.4505828618 0.03434613005833661 0.02290626629571447 3.155068121720569e-08 7.500991259377707 0.09935817652796874 TGQVYYNT(ph)DDEREGGSVLVK ddPTM_PC-9_AZD4547_30min_R2 1 TGQVYYNTDDEREGGSVLVK 20 1 Q6ISB3-2;Q6ISB3 Q6ISB3-2 GRHL2 Grainyhead-like protein 2 homolog 1 T(0.001)GQVY(0.004)Y(0.016)NT(0.967)DDEREGGS(0.012)VLVK 83.24700000000001 0.00066802 14882000.0 23336.0 23838.0 32562.0 43693.0 29454.0 28998.0 30445.0 36612.0 29982.0 32354.0 True False 30756.362581046465 31543.167322502828 32130.206604367177 33620.25390012076 25364.820513048046 27184.750475909812 33154.54602021999 30954.456660063202 31566.787310533855 31221.296307791174 0.9851084425783857 1.010309341788327 1.0291118692707575 1.076837219335154 0.8124204793738284 0.870711779802876 1.061920866237267 0.9914532809561344 1.011065876295997 1.0 14.930242818787 -10.849624151964104 14.686409600331382 0.9999999785555647 0.9823406153177263 0.004061673225491114 0.07777024883759634 0.0 0.0 0.08058930923045396 0.019545778485454475 1.4137605149257435e-11 10.849624151964104 -0.017659363237838344 TGQVYYNT(ph)DDEREGGSVLVK ddPTM_PC-9_Lapatinib_30min_R1 1 TGQVYYNTDDEREGGSVLVK 20 1 Q6ISB3-2;Q6ISB3 Q6ISB3-2 GRHL2 Grainyhead-like protein 2 homolog 1 TGQVYYNT(0.952)DDEREGGS(0.047)VLVK 98.26700000000001 0.00029555 22525000.0 34332.0 41966.0 43112.0 38963.0 43679.0 44515.0 42045.0 36760.0 47905.0 29232.0 True False 33842.4193842823 41868.830305383366 39567.49777713258 41828.468996757765 41109.88709621808 42611.197219533264 44221.884372235 38468.00379897774 42509.434437986216 34284.71225080839 0.9870994143602397 1.2212099083432193 1.154085747830642 1.2200326691022907 1.1990734177810916 1.242862909503595 1.289842657821703 1.1220162362036656 1.2398947416274113 1.0 15.065277793365482 -4.75735635471414 24.970309936390137 1.1967177726378004 0.9870991044146523 0.3718671847903353 0.07740191654152422 115.6124179284653 706946.9341116124 0.017730963482400726 0.1326848775343143 1.748411463488502e-05 4.75735635471414 -0.20961866822314812 TGQVYYNTDDEREGGS(ph)VLVK ddPTM_PC-9_AZD4547_30min_R2 1 TGQVYYNTDDEREGGSVLVK 20 1 Q6ISB3-2;Q6ISB3 Q6ISB3-2 GRHL2 Grainyhead-like protein 2 homolog 1 T(0.002)GQVY(0.006)Y(0.024)NT(0.435)DDEREGGS(0.533)VLVK 75.548 0.0014789000000000002 18340000.0 33337.0 43387.0 50121.0 66740.0 55609.0 56974.0 46531.0 66948.0 53880.0 57381.0 True False 43937.47254732374 57410.99927097203 49456.362791520354 51354.124122721245 47888.65023121099 53411.40677338043 50672.168857508856 56602.72491199371 56727.986801799925 55372.10865541707 0.793494660294562 1.0368216176892064 0.8931637965837522 0.9274366710919407 0.8648514819838999 0.9645904421982886 0.9151208087964261 1.0222244788298531 1.0244866626774238 1.0 15.756871842519214 -7.760869714189358 24.94201112445402 1.0175167008482269 0.9182039320671127 0.3774984861640792 0.059766284508196155 15.186738143918936 665037.3782519897 0.02814883807277655 0.014987894374083164 1.7343242068633815e-08 7.760869714189358 -0.09931276878111417 TGRDT(ph)PENGETAIGAENSEK ddPTM_PC-9_Lapatinib_30min_R1 2 TGRDTPENGETAIGAENSEK 20 1 Q8N3X1-2;Q8N3X1 Q8N3X1-2 FNBP4 Formin-binding protein 4 1 T(0.296)GRDT(0.704)PENGETAIGAENSEK;T(0.235)GRDT(0.765)PENGETAIGAENSEK 105.17 0.00010616 31868000.0 98414.0 142904.0 114229.0 107018.0 164393.0 131712.0 150640.0 162503.0 138517.0 159803.0 True False 97010.59831308274 142573.1145679956 104837.53255669156 114888.46072158283 154723.72694907346 126078.98479566806 158439.40211281914 170053.48262636748 122915.75681132523 187424.7356258872 0.517597626530591 0.7606952950574327 0.5593580388767604 0.6129845152931584 0.8255245842145018 0.6726912772459793 0.8453494763309961 0.9073161130972918 0.6558139532696134 1.0 17.515951841573965 -5.106923905746436 0.08622385475993909 1.2571814874004197 1.1882242704171104e-18 0.5380280967205185 0.10174841292343532 54.79448573775193 0.8486493351126914 3.3892178973038765 10.108870821761789 7.817647683255125e-06 5.106923905746436 -1.2571814874004197 TGS(ph)CSELDACPSK ddPTM_PC-9_AZD4547_30min_R2 2 TGSCSELDACPSK 13 0 A0A1B0GUA8;Q9H1H9-3;Q9H1H9-4;Q9H1H9-2;Q9H1H9;H0Y9Z7 A0A1B0GUA8 KIF13A Kinesin-like protein KIF13A 1 T(0.082)GS(0.901)CS(0.017)ELDACPSK;T(0.019)GS(0.981)CS(0.001)ELDACPSK 145.49 9.814100000000001e-05 66684000.0 108097.0 112850.0 100241.0 148351.0 131313.0 131108.0 129349.0 124027.0 111702.0 117605.0 True False 142469.5974427228 149326.5555979716 98911.73884369417 114150.96895010218 113082.4565773709 122909.79603405712 140860.81041778435 104861.47700692856 117606.33967584725 113487.68474617606 1.2553749577442435 1.3157952418533512 0.8715636332252075 1.0058445478503646 0.9964293203292367 1.0830232047552502 1.2411990845775944 0.9239899222674188 1.0362916464362004 1.0 16.792176224643782 -5.243153341732255 24.721558977153308 1.0259110752721599 1.285585162488996 0.5624537213916545 0.09364725647861621 545.0002343976485 736802.3843754252 0.024759375079866596 0.06523462407141302 5.71276893248932e-06 5.243153341732255 0.25967408721683616 TGS(ph)CSELDACPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TGSCSELDACPSK 13 0 A0A1B0GUA8;Q9H1H9-3;Q9H1H9-4;Q9H1H9-2;Q9H1H9;H0Y9Z7 A0A1B0GUA8 KIF13A Kinesin-like protein KIF13A 1 T(0.146)GS(0.828)CS(0.026)ELDACPSK;T(0.018)GS(0.969)CS(0.012)ELDACPSK;T(0.217)GS(0.748)CS(0.034)ELDACPSK;T(0.085)GS(0.898)CS(0.018)ELDACPSK 190.57 1.6051e-05 53028000.0 161451.0 174222.0 124119.0 185586.0 190218.0 140074.0 176920.0 168008.0 136314.0 127536.8 True False 188781.46549739683 191517.60876691376 127078.46768392845 175188.21809793 152946.1483913381 132728.2728538159 160160.85681012142 163597.96801919007 138307.33436924854 150658.2122592468 1.2530446410219511 1.2712059030499958 0.843488488136689 1.1628189095757548 1.0151862689579398 0.880989299311625 1.0630741889763224 1.0858881541596754 0.9180205466082039 1.0 17.20091978967106 -5.2378589808676255 24.8274093714094 1.0041555149160102 1.2621253716285195 0.5727540432796049 0.09166931031622146 509.5010647999377 536443.2085467284 0.022633853484721002 0.05980339345968705 5.782837906154703e-06 5.2378589808676255 0.25796985671250927 TGS(ph)CSELDACPSK ddPTM_PC-9_Lapatinib_30min_R1 1 TGSCSELDACPSK 13 0 A0A1B0GUA8;Q9H1H9-3;Q9H1H9-4;Q9H1H9-2;Q9H1H9;H0Y9Z7 A0A1B0GUA8 KIF13A Kinesin-like protein KIF13A 1 T(0.005)GS(0.7)CS(0.295)ELDACPSK 162.88 0.0003366 28854000.0 44048.0 57347.0 47826.0 42587.0 53104.0 48264.0 50735.0 53632.0 44441.0 45235.0 True False 43419.86744258608 57214.21654488916 43893.930893698795 45718.99004606734 49980.52712648102 46199.861228879134 53361.810051738474 56123.93851324196 39435.58659552333 53053.80947815128 0.8184118703194599 1.0784186302107341 0.8273473917414974 0.861747544535806 0.9420723529205589 0.8708113834484449 1.0058054374721959 1.0578682108841786 0.7433130058599048 1.0 15.695168725749207 -7.2506900561072865 24.496065009715984 0.9565690171876045 0.9048187960674492 0.054528404828048216 0.10394925398547598 1854.5421208321193 4226224.190707779 0.038820392120429065 0.029743232617075673 5.6144852328126723e-08 7.2506900561072865 -0.05175022112015526 TGS(ph)EPALSPAVVR ddPTM_PC-9_AZD4547_30min_R2 2 TGSEPALSPAVVR 13 0 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 T(0.002)GS(0.998)EPALSPAVVR;T(0.327)GS(0.673)EPALSPAVVR 146.67 6.3973e-05 36404000.0 64601.0 83586.0 84557.0 147250.0 121411.0 124419.0 101512.0 96092.0 93709.0 119822.0 True False 85142.77421572595 110603.53988668195 83435.71893143775 113303.78748982165 104555.1783564091 116639.06026147377 110546.37134519879 81243.18937448888 98662.26642928494 115627.06825097834 0.7363567675253717 0.956554045343497 0.7215933102302089 0.9799071203975024 0.9042448272532798 1.0087522067782504 0.9560596235584606 0.7026312316260035 0.8532800141151217 1.0 16.81911964615219 -4.745607501086268 24.626008137987284 0.8913204780609738 0.7363562456082733 0.1765180564137827 0.10388488233132917 1456.8277537890817 2265901.2827720745 0.026196120537630783 0.6395817068784031 1.796356372327321e-05 4.745607501086268 -0.15496423245270052 TGS(ph)EPALSPAVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TGSEPALSPAVVR 13 0 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 T(0.01)GS(0.989)EPALS(0.001)PAVVR;T(0.048)GS(0.946)EPALS(0.006)PAVVR;T(0.092)GS(0.907)EPALS(0.001)PAVVR;TGS(0.999)EPALS(0.001)PAVVR 171.99 0.00021461 37736300.0 47215.7 53730.3 39671.8 62980.0 64725.5 48416.3 56902.4 46436.0 48769.3 47992.9 True False 55208.38545741694 59064.28909281793 40617.72616813932 59451.4347839149 52043.00291088943 45877.26399597501 51512.19273429958 45217.10420300897 49482.45875004902 56693.63285841266 0.9738022185894314 1.0418152112482504 0.7164424666448612 1.0486439444159383 0.9179690961216445 0.8092136926654431 0.9086063132159254 0.7975693552031617 0.8728045153434971 1.0 15.790899097796412 -6.537244585344457 23.390569242637063 0.8665521839102105 0.941686389821232 0.08662299422838382 0.10044612737426545 251.12476346740084 408877.66711667384 0.03212476520326396 0.03214326712116258 2.9023876315922827e-07 6.537244585344457 0.07513420591102149 TGS(ph)EPALSPAVVR ddPTM_PC-9_Lapatinib_30min_R1 3 TGSEPALSPAVVR 13 0 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 T(0.336)GS(0.664)EPALSPAVVR;T(0.339)GS(0.661)EPALSPAVVR;T(0.004)GS(0.994)EPALS(0.003)PAVVR 171.99 0.00021461 62493000.0 124765.0 118933.0 116089.0 110663.0 91512.0 115200.0 96418.0 91212.0 105327.0 88590.0 True False 122985.82822090122 118657.61794572156 106544.61053649892 118801.52618094598 86129.44407951432 110273.16454431608 101410.05226310273 95450.04250577682 93463.96411751944 103902.66346124516 1.1836638650439786 1.142007471155731 1.0254271352364244 1.143392500474812 0.8289435632382984 1.061312201928751 0.9760101318377449 0.9186486594867599 0.8995338618281016 1.0 16.664873111480468 -5.360130910497636 0.671716548158959 0.9442305509770362 1.2447227418376128 0.5324462110609407 0.07559116158019318 1.3383129425385072 0.7542072997419833 0.03701419816155942 0.27559582392652554 4.363842719844787e-06 5.360130910497636 0.30049219086057655 TGS(ph)ES(ph)SQTGTSTTSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 T(0.412)GS(0.588)ES(0.989)S(0.011)QT(0.001)GTSTTSSR 126.07 0.00035735 20297000.0 31050.0 38204.0 29779.0 33230.0 35200.0 29328.0 46766.0 43107.0 35771.0 31650.0 True False 36306.15173454584 41996.64063855994 30489.044297486405 31368.230833113572 28302.812685314268 27789.988051006716 42335.98592348043 41975.486925641875 36294.08320291663 37387.89445873783 0.9710670327962484 1.1232684067006884 0.8154790404454265 0.8389943131922634 0.7570047229204074 0.7432883946346968 1.1323447478488908 1.12270261626974 0.9707442403040814 1.0 15.190283606041863 -7.274334667430526 24.987606763492106 1.0666731234382947 0.8764569157469907 0.38061525558666376 0.11317736538582525 921.9046488557126 1786396.8975297608 0.052470698505013645 0.0356358716136311 5.316983744652316e-08 7.274334667430526 -0.19021620769130398 TGS(ph)ESS(ph)QTGTSTTSSR ddPTM_PC-9_AZD4547_30min_R2 1 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 T(0.114)GS(0.886)ES(0.077)S(0.674)QT(0.109)GT(0.109)S(0.024)T(0.005)T(0.001)SSR 92.8 0.035575 17659000.0 16519.0 14328.0 12690.0 13621.0 12430.0 13857.0 14894.0 13287.0 16690.0 14390.0 True False 21771.69838345505 18959.245800688856 12521.72230850129 10480.888892352203 10704.309057417919 12990.519599444182 16219.53714649883 11233.799454885278 17572.199326689682 13886.21047997511 1.567864639157772 1.3653289951228536 0.9017379022562342 0.7547695541174736 0.7708589087609095 0.9354978176499212 1.1680319241803614 0.8089895707029074 1.265442386317709 1.0 13.761365323889425 -5.130215760863523 3.3938949535929357 0.9373419716319775 1.5354815089160696 0.6398760155659724 0.15747126153843377 0.15096751049897522 3.1249723197773065 0.04218822679026549 0.1436328031216125 7.409420440985523e-06 5.130215760863523 0.5981395372840921 TGS(ph)ESS(ph)QTGTSTTSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 T(0.096)GS(0.904)ES(0.1)S(0.872)QT(0.02)GT(0.006)S(0.001)TTSSR 113.52 0.0027321999999999997 6244000.0 8353.7 13135.0 9689.1 11546.0 12327.0 11102.0 15958.0 13914.0 13016.0 11358.0 True False 9767.81641690421 14438.955993809142 9920.124890116369 10899.11505263705 9911.612840109912 10519.791576045982 14446.342714085033 13548.77224310162 13206.334376147239 13417.115490121472 0.7280116522881459 1.0761594773809626 0.7393634568786556 0.8123292268492185 0.7387290395918159 0.7840576153489411 1.0767100219657006 1.0098125974302807 0.9842901319490449 1.0 13.71178692326366 -7.257255568073236 24.951340248254926 1.0185209068562375 0.8182969322624066 0.5178298159381486 0.09663881197327537 299.75868878612806 1787702.4980300732 0.03819533148476707 0.028478572523046745 5.5302457659863764e-08 7.257255568073236 -0.2002239745938309 TGS(ph)ESS(ph)QTGTSTTSSR ddPTM_PC-9_Lapatinib_30min_R1 1 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 T(0.184)GS(0.816)ES(0.293)S(0.65)QT(0.055)GT(0.001)STTSSR 119.04 0.0013985999999999998 5629300.0 3755.9 5637.4 5007.1 5026.2 8961.3 7210.4 7748.1 7117.4 7520.3 6410.8 True False 3702.3401772522966 5624.346946660821 4595.435565964942 5395.843514911679 8434.213952593664 6902.028000263342 8149.258706255538 7448.1003873461395 6673.284621730248 7518.898238145949 0.4924046130148504 0.7480280712041799 0.6111847002597697 0.7176375240107274 1.1217353507730699 0.9179573631209672 1.083836813339427 0.990584012636236 0.8875349034349722 1.0 12.87630556055244 -6.116689555397657 4.7934165737322125 0.9988034779327738 0.6349046713542118 0.8045708720657423 0.08720549059223826 0.09483433704282267 3.3306809754617652 0.02494221358321862 0.03282780686859052 7.643819877754054e-07 6.116689555397657 -0.363898806578562 TGS(ph)ESSQT(ph)GTSTTSSR ddPTM_PC-9_Lapatinib_30min_R1 1 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 T(0.2)GS(0.793)ES(0.006)S(0.111)QT(0.545)GT(0.243)S(0.054)T(0.04)T(0.002)S(0.004)S(0.003)R 107.73 0.0233 2961700.0 7182.8 8545.2 5467.7 8591.9 11471.0 10366.0 13724.0 13843.0 12898.0 12834.0 True False 7080.371954835801 8525.414114415524 5018.1668119323585 9223.776987738187 10796.298332853708 9922.670344326227 14434.561567952276 14486.196316356065 11445.291418038743 15052.339799769945 0.47038347851700874 0.5663846437047497 0.33338118051314886 0.6127802793741848 0.7172505056668144 0.6592111576220118 0.9589579932398875 0.9623883402218616 0.7603662666593316 1.0 13.877700142624194 -6.660829154460346 0.9854381239248862 0.9235850275851034 0.4660794909250706 0.7762527202224951 0.0996642592896111 0.24865692703756143 0.5222802522429555 0.05506835279348877 0.05579578988820052 2.1835887370034923e-07 6.660829154460346 -0.4575055366600328 TGS(ph)ESSQTGTSTTSSR ddPTM_PC-9_AZD4547_30min_R2 8 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 T(0.123)GS(0.86)ES(0.018)SQTGTSTTSSR;T(0.001)GS(0.997)ESS(0.001)QTGTS(0.001)T(0.001)TSSR;T(0.003)GS(0.997)ESSQTGTSTTSSR;T(0.008)GS(0.876)ES(0.1)S(0.008)QT(0.008)GTSTTSSR;T(0.014)GS(0.984)ES(0.003)SQTGTSTTSSR;T(0.015)GS(0.985)ESSQTGTSTTSSR;T(0.01)GS(0.981)ES(0.008)S(0.001)QTGTSTTSSR;T(0.123)GS(0.875)ES(0.001)SQTGTSTTSSR 342.97 5.460199999999997e-213 624670290.0 107307.03 122188.77 118877.66999999998 127428.75 131652.52000000002 110502.51 110622.68000000002 132194.94000000003 115438.71000000002 131518.6 True False 141428.4334151198 161683.90037087057 117301.27442251024 98052.02044206184 113374.84008591282 103592.77058113413 120467.88421547267 111767.24956051749 121540.56453780274 126914.17384514633 1.114362794400592 1.2739625171271125 0.9242566914995229 0.7725852635001943 0.8933189781012681 0.81624272090785 0.949207488538364 0.8806522248404636 0.9576595021301547 1.0 16.953493673593833 -5.329432870296469 6.0606404741704605 0.8874474490987777 1.19317412394956 0.7222018001466126 0.07301357125664894 0.09418088472664382 6.501705206837293 0.018373713786379756 0.0392408971190884 4.68346338941143e-06 5.329432870296469 0.3057266748507822 TGS(ph)ESSQTGTSTTSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 TGS(0.758)ES(0.237)S(0.005)QTGTSTTSSR;T(0.004)GS(0.992)ES(0.003)S(0.001)QTGTSTTSSR;T(0.087)GS(0.634)ES(0.181)S(0.098)QTGTSTTSSR;T(0.217)GS(0.781)ES(0.001)S(0.001)QTGTSTTSSR;T(0.001)GS(0.994)ES(0.005)SQTGTSTTSSR;T(0.041)GS(0.848)ES(0.057)S(0.022)QT(0.01)GT(0.002)S(0.001)T(0.001)T(0.001)S(0.008)S(0.008)R;T(0.172)GS(0.824)ES(0.003)S(0.001)QTGTSTTSSR 296.51 9.6586e-112 493216550.0 50363.909999999996 63718.45 56234.119999999995 67029.00000000001 90207.73 81318.36000000002 113926.50000000001 107280.19999999998 86909.94999999998 77911.52 True False 58889.525230435116 70043.99661543423 57574.95468988771 63273.582440950035 72532.17286810794 77053.88204880866 103134.55716356747 104464.20842276787 88180.84360127806 92036.26182874691 0.6398513375088141 0.7610478220613308 0.625568157005531 0.6874853583110972 0.7880825603615835 0.8372122087290317 1.1205861158884451 1.1350331526626516 0.9581097911751058 1.0 16.489914767385137 -6.9521470226744215 1.9853556770938021 1.0646003685680345 0.6890577287306576 0.8578270903394114 0.06757875813112227 0.11288596061099426 0.9015814381154033 0.029248713136277284 0.023464454477394432 1.1164852175788906e-07 6.9521470226744215 -0.3755426398373769 TGS(ph)ESSQTGTSTTSSR ddPTM_PC-9_Lapatinib_30min_R1 7 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 T(0.216)GS(0.732)ES(0.053)SQTGTSTTSSR;T(0.059)GS(0.937)ES(0.004)SQTGTSTTSSR;T(0.011)GS(0.865)ES(0.125)SQTGTSTTSSR;T(0.081)GS(0.918)ESSQTGTSTTSSR;T(0.019)GS(0.966)ES(0.01)S(0.003)QT(0.001)GT(0.001)S(0.001)TTSSR;T(0.012)GS(0.775)ES(0.158)S(0.043)QT(0.012)GTSTTSSR;T(0.012)GS(0.975)ES(0.012)S(0.001)QTGTSTTSSR 339.81 9.980299999999994e-190 994822680.0 34902.75 51772.950000000004 43701.47 53199.87 70762.06000000001 59699.44 74369.88 85225.05 72901.82 70851.15000000001 True False 34405.03038461955 51653.072915195575 40108.50382915257 57112.36590936382 66599.97475436277 57146.234117391774 78220.38849178243 89184.91695234143 64690.84934140216 83097.67687427676 0.41403119411717004 0.6215946685650968 0.4826669690156925 0.687291968411733 0.8014661451381571 0.6876995394690948 0.9413065615555841 1.0732540343729995 0.7784916711844623 1.0 16.3425205243091 -6.327081960515464 0.581072375424488 0.9789001065639712 0.4382777643169243 0.7544836650848411 0.10102295587075609 0.4909236256750838 0.3473140014750824 0.07473968483633942 0.13956287722595806 4.7088845144270245e-07 6.327081960515464 -0.5406223422470469 down TGS(ph)GQGPSSTGQPGR ddPTM_PC-9_AZD4547_30min_R2 1 TGSGQGPSSTGQPGR 15 0 Q8IVF2-3;Q8IVF2 Q8IVF2-3 AHNAK2 Protein AHNAK2 1 T(0.005)GS(0.994)GQGPSSTGQPGR 94.882 0.015324 0.0 587.65 2930.6 892.39 2445.3 3121.6 3531.1 2245.3 2306.5 2375.9 2310.3 True False 774.5104761206702 3877.8591389934886 880.5563255227327 1881.5738645083936 2688.2197227381935 3310.2997587931995 2445.1273502775493 1950.0834230972291 2501.485223504017 2229.4171002005905 0.34740492304063875 1.739404949681502 0.3949715490401079 0.843975703038745 1.205794879072347 1.4848274728382398 1.0967563449915003 0.8747055106564723 1.1220355416126249 1.0 11.122450839392133 -6.255545737743866 23.844613134771702 1.1404324263143197 0.865117686114826 0.12494992853085984 0.3833206785887563 616.0700850240675 2492500.4115105714 0.11190605323850968 0.14043873350509356 5.5520614247938e-07 6.255545737743866 -0.27531474019949376 TGS(ph)GQGPSSTGQPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TGSGQGPSSTGQPGR 15 0 Q8IVF2-3;Q8IVF2 Q8IVF2-3 AHNAK2 Protein AHNAK2 1 T(0.221)GS(0.487)GQGPS(0.221)S(0.069)T(0.003)GQPGR;T(0.079)GS(0.915)GQGPS(0.004)S(0.001)TGQPGR 132.25 0.00013248 0.0 7497.6 5439.6 6094.6 5769.0 5085.3099999999995 6102.8 3374.8 4367.9 2081.41 2240.62 True False 8766.795595649955 5979.607538935988 6239.918377899213 5445.781633350353 4088.8800107032803 5782.758424634605 3055.114512563865 4253.247253172598 2111.8466836091443 2646.826669261838 3.312191046531539 2.259160982613045 2.3575092582996513 2.057475729934784 1.5448234892704968 2.1847892390502976 1.1542556027727695 1.6069232271861487 0.7978787232781314 1.0 11.370048005908675 -1.522878745281469 0.20773903870283655 0.8416862993122018 12.115602146712185 0.8104291875733403 0.3133284091841339 21.0164064636934 0.25992954667103635 0.5126924501231496 78.01603120007667 0.029999999999921846 1.522878745281469 11.273915847399984 up TGS(ph)GQGPSSTGQPGR ddPTM_PC-9_Lapatinib_30min_R1 1 TGSGQGPSSTGQPGR 15 0 Q8IVF2-3;Q8IVF2 Q8IVF2-3 AHNAK2 Protein AHNAK2 1 T(0.316)GS(0.674)GQGPS(0.01)STGQPGR 118.05 0.00011905 1524900.0 2396.0 4036.6 2493.9 3485.5 2153.5 1149.1 596.96 1232.8 1194.7 2323.4 True False 2361.8326006274133 4027.253500707963 2288.861168732393 3741.8352972871467 2026.8353639438992 1099.955671682931 627.8676678522869 1290.0803885576645 1060.1403052512705 2724.9965942641 0.8667286431105573 1.4778930400078332 0.8399501025249949 1.373152283993092 0.743793723709683 0.4036539619896222 0.23041044130987104 0.4734245874923956 0.38904280008378034 1.0 11.412038711453903 -6.501388522715693 4.031853990969774 0.4547028327578328 1.1403561632410484 0.5646546026995182 0.2631159581122531 0.14229454205597578 5.220002171020248 0.08107305124335677 0.08744569130609146 3.1521833975049236e-07 6.501388522715693 0.6856533304832155 TGS(ph)HSEPQAR ddPTM_PC-9_AZD4547_30min_R2 1 TGSHSEPQAR 10 0 Q9NZB2-4;Q9NZB2;Q9NZB2-6;Q9NZB2-2;Q9NZB2-5;A0A0C4DH52 Q9NZB2-4 FAM120A Constitutive coactivator of PPAR-gamma-like protein 1 1 T(0.005)GS(0.988)HS(0.007)EPQAR 81.92 0.015625 1559100.0 4562.9 5104.2 5032.7 8038.7 7675.3 4701.8 5664.5 6209.1 4397.8 5154.7 True False 6013.807285784068 6754.032831928808 4965.9631096922385 6185.501911676945 6609.717080321779 4407.795702725458 6168.6295264094615 5249.626265923696 4630.258729713355 4974.235521968571 1.2089912629235702 1.3578031844491103 0.9983369480114486 1.2435080495000388 1.3287905349736957 0.8861252514599585 1.2401160940542286 1.0553634307701896 0.9308483101099551 1.0 12.280259103099855 -7.2816215543356355 0.5523150399699717 0.9703830866276189 1.236185609300718 0.29368634610199884 0.1358663188865229 1.1530358802351106 0.7372408153669469 0.12623857876128736 0.10096053897114929 5.228516051825467e-08 7.2816215543356355 0.2658025226730991 TGS(ph)HSEPQAR ddPTM_PC-9_Lapatinib_30min_R1 2 TGSHSEPQAR 10 0 Q9NZB2-4;Q9NZB2;Q9NZB2-6;Q9NZB2-2;Q9NZB2-5;A0A0C4DH52 Q9NZB2-4 FAM120A Constitutive coactivator of PPAR-gamma-like protein 1 1 T(0.001)GS(0.994)HS(0.006)EPQAR;T(0.001)GS(0.994)HS(0.006)EPQAR 108.35 0.0020408 3615000.0 15991.3 19190.6 21011.7 17996.2 19921.1 18021.2 19324.2 18366.9 19926.3 18201.699999999997 True False 15763.26112955473 19146.16534476695 19284.199133507536 19319.70058156332 18749.38006438951 17250.47528546903 20324.712521963218 19220.293225664973 17681.990260758685 21347.83959275927 0.7384007670219376 0.8968666483357369 0.9033325854691322 0.9049955850387854 0.8782799768998123 0.8080665591716374 0.9520735076563404 0.9003390315984989 0.8282800788308358 1.0 14.381802455647293 -14.522878745280336 0.17099266776937555 1.4715454948952036 0.8449617773192973 0.32532427214215665 0.05770396367797547 172.84427086220936 1.6287153690195786 27.92607428532909 0.20594311349503788 3.0000000000000132e-15 14.522878745280336 -0.6265837175759063 TGS(ph)LTDEPADPAR ddPTM_PC-9_AZD4547_30min_R2 1 TGSLTDEPADPAR 13 0 Q8IWY9-1;Q8IWY9 Q8IWY9-1 CDAN1 Codanin-1 1 T(0.278)GS(0.722)LTDEPADPAR 104.17 0.0036228000000000002 0.0 13355.0 13903.0 15889.0 20989.0 17025.0 15493.0 11258.0 18069.0 10805.0 12325.0 True False 17601.61219874339 18396.872862016822 15678.301478311827 16150.310326817445 14661.372622891387 14524.220260820426 12259.940190364156 15276.851234313397 11376.13024115531 11893.505501438025 1.479934759067897 1.5467998782858834 1.3182237546715043 1.357910022815791 1.2327208846137672 1.2211891825386827 1.0308096455567137 1.2844700187397482 0.9564993466207116 1.0 13.5378863784144 -5.498490556256054 0.30810901963036214 0.9882787754260649 1.7974461653436602 0.78941989673007 0.08655312466907414 2.067140518196716 0.22536234404422936 0.0961498880232491 0.6078252848515053 3.1732876663024756e-06 5.498490556256054 0.8091673899175953 TGS(ph)LTDEPADPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TGSLTDEPADPAR 13 0 Q8IWY9-1;Q8IWY9 Q8IWY9-1 CDAN1 Codanin-1 1 T(0.173)GS(0.826)LT(0.001)DEPADPAR;T(0.183)GS(0.806)LT(0.011)DEPADPAR 117.7 0.00025458 11063900.0 30004.0 37161.0 72636.0 37783.0 49514.0 31720.0 28184.1 43789.0 33191.0 25455.0 True False 35083.08459398756 40850.09849150677 74367.917713564 35666.141004138735 39812.087139223026 30056.54736013137 25514.29801278631 42639.58514828065 33676.35558379711 30069.78999833088 1.1667219689906365 1.3585096036179263 2.4731771561321856 1.1861120748139078 1.3239895304035352 0.9995596032363298 0.8485027003581521 1.4180207161622176 1.1199398328244534 1.0 14.87602717198998 -5.96199664542997 24.99975032913125 1.1320997110743485 1.6677523964853125 0.33192957461557304 0.35064747295101495 195.04281950939043 128303.86096512845 0.10062990760469726 0.14925797625974932 1.0914487669661477e-06 5.96199664542997 0.535652685410964 TGS(ph)LTDEPADPAR ddPTM_PC-9_Lapatinib_30min_R1 2 TGSLTDEPADPAR 13 0 Q8IWY9-1;Q8IWY9 Q8IWY9-1 CDAN1 Codanin-1 1 T(0.056)GS(0.916)LT(0.028)DEPADPAR;T(0.073)GS(0.814)LT(0.113)DEPADPAR 131.08 7.2653e-05 9336500.0 37023.0 42865.0 38208.0 37323.0 34968.0 35139.0 24084.3 29560.0 37933.0 36129.0 True False 36495.04523081331 42765.74872611772 35066.685727145166 40067.85792587814 32911.25098973312 33636.18688300977 25331.267208615056 30933.46551408546 33660.5860878015 42373.84951113359 0.8612633889027326 1.009248610157101 0.8275548748038932 0.9455798420049244 0.776687777235953 0.7937958734235834 0.5978042472152394 0.730013106455145 0.7943716815003389 1.0 15.370886577837025 -6.336902727215037 5.016755702333107 0.7581177501418146 0.9118750169732617 0.2523631216793476 0.10396607283544126 0.2586848585412934 11.94830503764163 0.03168770801678984 0.03629847579390369 4.603596728717361e-07 6.336902727215037 0.15375726683144708 TGS(ph)NAAQYK ddPTM_PC-9_AZD4547_30min_R2 3 TGSNAAQYK 9 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 T(0.012)GS(0.988)NAAQYK;T(0.363)GS(0.637)NAAQYK;T(0.003)GS(0.997)NAAQYK 92.24700000000001 0.0071763999999999994 259747000.0 138107.0 127776.0 107283.0 155531.0 138762.0 151701.0 149413.0 129556.0 127043.0 132466.0 True False 182022.15319594537 169077.09320413295 105860.35732253306 119675.73087999634 119497.29150647022 142215.11248865453 162710.46754866565 109536.09710070862 133758.23361657507 127828.40565951214 1.4239570012379366 1.3226879607220647 0.8281442358321055 0.9362217283595672 0.9348257993983518 1.1125470254824525 1.2728819287793238 0.8568995016058676 1.0463889690751351 1.0 16.963848937877174 -5.118092285414133 5.507348584153257 1.003593065596622 1.3997106891207398 0.6046802657666588 0.12216442208012054 0.14796638614234617 5.956714325780529 0.03310443166577983 0.09292936525891238 7.619170892360758e-06 5.118092285414133 0.3961176235241177 TGS(ph)NAAQYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TGSNAAQYK 9 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 T(0.49)GS(0.51)NAAQYK;T(0.319)GS(0.679)NAAQY(0.002)K;T(0.11)GS(0.89)NAAQYK;T(0.406)GS(0.594)NAAQYK 97.911 0.004631399999999999 256025000.0 318153.0 319358.0 198940.0 308809.0 328544.0 243527.0 334393.0 327543.0 259653.0 225540.0 True False 372010.0190918184 351061.7516765057 203683.48408415125 291507.43290228624 264168.1616728379 230756.01541521787 302716.8742443308 318945.34331049497 263449.9339097843 266428.61662634247 1.3962840170939688 1.3176578256563878 0.7644955210265973 1.094129589356822 0.9915157201124729 0.8661082219213927 1.1362025524040513 1.1971136860189666 0.9888199595288382 1.0 18.023389522490334 -5.096416637148062 7.373463472467605 1.014659837975549 1.3771613754959788 0.5869214932516141 0.11871908479651709 0.16823684267231045 11.052649319168633 0.03087733076907495 0.08334161946213542 8.009093483505787e-06 5.096416637148062 0.3625015375204299 TGS(ph)NAAQYK ddPTM_PC-9_Lapatinib_30min_R1 1 TGSNAAQYK 9 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 T(0.44)GS(0.56)NAAQYK 68.44 0.043051 91642000.0 29478.0 21601.0 24272.0 31348.0 27283.0 28538.0 27495.0 22280.0 25436.0 21506.0 True False 29057.638314396878 21550.984211661485 22276.44985262947 33653.43649386245 25678.267580441803 27317.496265327216 28918.556565931773 23315.210137138834 22571.129827045563 25223.28344505628 1.1520164842017078 0.8544083587930119 0.8831701035733163 1.334221080580945 1.0180382596253423 1.0830269708871467 1.146502461859293 0.9243526992798622 0.8948529590214578 1.0 14.62246847050368 -7.78608830157614 24.558481746128383 0.9322019664402913 1.061039077621197 0.16328210786394282 0.1315023195773697 377.14518130099157 375754.6262837069 0.07431860323772059 0.03573026583266277 1.6364837546248622e-08 7.78608830157614 0.1288371111809058 TGS(ph)NISGASSDISLDEQYK ddPTM_PC-9_AZD4547_30min_R2 1 TGSNISGASSDISLDEQYK 19 0 P22059 P22059 OSBP Oxysterol-binding protein 1 1 T(0.098)GS(0.896)NIS(0.005)GASSDISLDEQYK 274.68 9.060099999999997e-92 9599900.0 24584.0 26070.0 25083.0 36445.0 35412.0 48713.0 54797.0 47453.0 56007.0 48558.0 True False 32401.20062103387 34496.61767336391 24750.383031058947 28043.16831963702 30495.655055614083 45666.968409303925 59673.82684414505 40120.22921146018 58967.415679443366 46857.99919990493 0.6914764004925675 0.7361948495964356 0.5281997407842621 0.598471313297003 0.6508100127261933 0.9745821244838081 1.273503518354794 0.8562087561677533 1.2584279458428733 1.0 15.516007733110278 -6.831230849170326 3.787354676662658 1.089348697281674 0.6349975536652082 0.757305405694458 0.12348946610747744 0.1073452224260033 3.0488008602046124 0.042978793040430126 0.038465386538507285 1.47492233011721e-07 6.831230849170326 -0.4543511436164658 TGS(ph)PGPELLFHEGQQK ddPTM_PC-9_AZD4547_30min_R2 3 TGSPGPELLFHEGQQK 16 0 A6NHN7;A6NHB5;Q14202-2;Q14202;A6NL54;Q14202-3 A6NHN7 ZMYM3 Zinc finger MYM-type protein 3 1 T(0.431)GS(0.569)PGPELLFHEGQQK;T(0.141)GS(0.859)PGPELLFHEGQQK;T(0.082)GS(0.918)PGPELLFHEGQQK 163.9 1.3825999999999998e-15 40684000.0 154883.0 167907.0 147618.0 159712.0 151164.0 187227.0 142097.0 176507.0 168610.0 178266.0 True False 204132.57223346844 222179.6541496552 145660.4888681121 122892.86592580228 130177.48788057291 175519.66609259855 154743.3577216356 149231.89887735632 177522.3803758629 172024.96159994754 1.1866450678721192 1.2915547376568806 0.846740423676726 0.7143897303206244 0.7567360380135241 1.0203151011350209 0.8995401381428519 0.8675014224063738 1.031957099276673 1.0 17.392258396129186 -5.263200035232725 24.993148277682245 0.8810722177771664 1.2390999235547522 0.642227079813065 0.10331898304444681 88.81965071798102 1260848.350977074 0.028283365905092155 0.06417900289243933 5.455065439154186e-06 5.263200035232725 0.3580277057775858 TGS(ph)PGPELLFHEGQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TGSPGPELLFHEGQQK 16 0 A6NHN7;A6NHB5;Q14202-2;Q14202;A6NL54;Q14202-3 A6NHN7 ZMYM3 Zinc finger MYM-type protein 3 1 T(0.441)GS(0.559)PGPELLFHEGQQK;T(0.151)GS(0.849)PGPELLFHEGQQK 117.27 8.233700000000001e-05 20136000.0 81934.0 104824.0 83693.0 104859.0 89944.0 72976.0 106044.0 80393.0 65153.0 76277.0 True False 95803.80792973541 115230.23396231803 85688.55852746996 98984.09018746467 72320.11886840631 69149.01009309418 95998.74462792561 78282.76893342435 66105.7393676338 90105.41629160043 1.0632413885053675 1.2788380399842814 0.950981217934374 1.098536517129347 0.8026167776015031 0.7674234573126345 1.065404817810875 0.868790935720052 0.7336488980163131 1.0 16.45932620947476 -5.827791390535041 1.501658397989014 0.8749116223129514 1.154130711173818 0.4230781419475912 0.12379154280460601 0.37768254541872903 1.729190059032553 0.04079297915774272 0.08596650719491192 1.486649569615716e-06 5.827791390535041 0.27921908886086655 TGS(ph)PGPELLFHEGQQK ddPTM_PC-9_Lapatinib_30min_R1 3 TGSPGPELLFHEGQQK 16 0 A6NHN7;A6NHB5;Q14202-2;Q14202;A6NL54;Q14202-3 A6NHN7 ZMYM3 Zinc finger MYM-type protein 3 1 T(0.215)GS(0.785)PGPELLFHEGQQK;T(0.405)GS(0.595)PGPELLFHEGQQK;T(0.26)GS(0.74)PGPELLFHEGQQK 161.75 1.5282e-05 32296800.0 79018.0 116278.0 95550.0 106251.0 113977.0 112373.0 126801.0 111692.0 102136.0 91961.0 True False 77891.18882987367 116008.76543509909 87694.24783366623 114065.05298294552 107273.09694740378 107567.06874425741 133366.1353379421 116881.61807169246 90632.3681402392 107856.33631967015 0.7221753629663051 1.075586000726618 0.8130653314030017 1.0575646909132315 0.9945924422044363 0.9973180289143571 1.2365164615147384 1.0836787346945729 0.8403063856315156 1.0 16.71875140854707 -5.776204565560533 24.945475516844766 1.039251519606388 0.8908066045883147 0.25049268277609804 0.12438607545506074 329.5413610100192 556752.5756892661 0.03474013090343231 0.05177259282055146 1.6741541141160859e-06 5.776204565560533 -0.14844491501807333 TGS(ph)PGSPGAGGVQSTAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGSPGSPGAGGVQSTAK 17 0 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 T(0.128)GS(0.53)PGS(0.342)PGAGGVQSTAK 168.42 1.8887e-05 5579400.0 13555.0 16402.0 13393.0 12212.0 16706.0 12654.0 14764.0 12751.0 15233.0 10851.0 True False 15849.5937765465 18030.28216295833 13712.33991323535 11527.801231838183 13432.579225024432 11990.401963906132 13365.447037896449 12416.299760801263 15455.7538069953 12818.200403531262 1.2364913386890195 1.4066157179124148 1.0697554634469408 0.8993307070360992 1.047930193174692 0.9354200735231849 1.0426929379427106 0.9686460946094055 1.2057662792303843 1.0 13.645906110215728 -5.371926334645812 5.140785683435508 1.0107098256199654 1.3190924940887971 0.6582148838306037 0.0870752528097014 0.11467157854225873 4.4090443023231085 0.02185115364690798 0.04702969974732801 4.246915943424478e-06 5.371926334645812 0.3083826684688318 TGS(ph)PTFVR ddPTM_PC-9_AZD4547_30min_R2 1 TGSPTFVR 8 0 Q9UPP1-4;Q9UPP1-3;Q9UPP1-2;Q9UPP1;Q9UPP1-5;B0QZZ4;Q5JPR8;B0QZZ2;B0QZZ3;B0QZE1 Q9UPP1-4 PHF8 Histone lysine demethylase PHF8 1 T(0.012)GS(0.906)PT(0.082)FVR 109.44 0.003778 10893000.0 69367.0 79309.0 118740.0 138330.0 111000.0 116790.0 81232.0 152630.0 98913.0 103290.0 True False 91424.26307676772 104944.08327797541 117165.43001666229 106440.15567719557 95589.56599946818 109487.10283748883 88461.49063276434 129044.54058848064 104141.33924510832 99673.84853902928 0.9172342035229906 1.0528747993199286 1.1754881720131818 1.0678844775971181 0.9590235292463718 1.0984536510057297 0.8875095316313133 1.2946679844307474 1.0448210917062133 1.0 16.6049274134402 -7.752905014205575 24.999992064222404 1.1273084230573607 1.0318896379644957 0.12026460552226836 0.10821698258250527 357.68835737724004 1047796.2319641418 0.05045158814776858 0.02852622714082235 1.7664241181366045e-08 7.752905014205575 -0.09541878509286494 TGS(ph)PTFVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGSPTFVR 8 0 Q9UPP1-4;Q9UPP1-3;Q9UPP1-2;Q9UPP1;Q9UPP1-5;B0QZZ4;Q5JPR8;B0QZZ2;B0QZZ3;B0QZE1 Q9UPP1-4 PHF8 Histone lysine demethylase PHF8 1 T(0.074)GS(0.879)PT(0.047)FVR 86.898 0.01213 8081900.0 51517.0 56726.0 64040.0 64923.0 83949.0 70324.0 71197.0 56907.0 56135.0 35905.0 True False 60237.810592869486 62357.382390926345 65566.95647305234 61285.574793205946 67499.79608293874 66636.08564167334 64452.704738357665 55413.251547950495 56955.86817801363 42414.29227617641 1.4202243479777292 1.4701974038584094 1.5458693981292833 1.4449274408294042 1.591439876997607 1.5710762119471227 1.5195987314530757 1.3064759205961203 1.342846128544388 1.0 15.372262868902311 -8.59385130127393 0.9840867694717311 1.005928288239478 1.5117006708746121 0.8386593421028791 0.06677242695178326 0.24531993957847184 0.5144150725839745 0.06607369108977001 0.021977343009393805 2.5477024148409964e-09 8.59385130127393 0.5057723826351341 TGS(ph)PTFVR ddPTM_PC-9_Lapatinib_30min_R1 2 TGSPTFVR 8 0 Q9UPP1-4;Q9UPP1-3;Q9UPP1-2;Q9UPP1;Q9UPP1-5;B0QZZ4;Q5JPR8;B0QZZ2;B0QZZ3;B0QZE1 Q9UPP1-4 PHF8 Histone lysine demethylase PHF8 1 T(0.116)GS(0.861)PT(0.024)FVR;T(0.061)GS(0.729)PT(0.21)FVR 91.265 0.0088545 28254000.0 176276.0 142925.0 250110.0 131682.0 168809.0 210010.0 131402.0 139209.0 248410.0 129437.0 True False 173762.27191494082 142594.06594378612 229546.92125252 141366.333558275 158879.98651126344 201028.36185722105 138205.35260507624 145677.15834743966 220431.44992673345 151810.01298603904 1.1446034981297353 0.9392928907587904 1.5120670681559714 0.9312055955839719 1.0465711937319615 1.324210161787604 0.9103836425979759 0.9596017777881135 1.4520218106232892 1.0 17.211907424669064 TGS(ph)QEGTSMEGSR ddPTM_PC-9_AZD4547_30min_R2 2 TGSQEGTSMEGSR 13 0 Q8IV36-3;Q8IV36-2;Q8IV36 Q8IV36-3 HID1 Protein HID1 1 T(0.24)GS(0.76)QEGTSMEGSR;T(0.023)GS(0.975)QEGT(0.002)S(0.001)MEGSR 93.228 0.0037210999999999998 3933300.0 24409.0 43307.0 23594.0 19442.2 19957.3 28066.0 28296.0 25149.0 27910.0 20816.0 True False 32170.554261260026 57305.14083545729 23281.128143954265 14960.10116899566 17186.57338307373 26311.02858324317 30814.28918338462 21262.79991652817 29385.265620605725 20087.238175897295 1.601541933219148 2.8528133302176806 1.1590009507573482 0.7447564985288174 0.8555966346680711 1.3098380351169336 1.534023189925568 1.058522815846403 1.4628823217651268 1.0 14.293991598979561 -5.286860435557849 23.339489120766025 1.1384496926092786 2.2271773489620394 0.5859418419954281 0.36536669769505964 188.22067401942266 172808.31823202738 0.09397277871470862 0.19578271976322484 5.165823509905853e-06 5.286860435557849 1.0887276563527608 TGS(ph)QEGTSMEGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TGSQEGTSMEGSR 13 0 Q8IV36-3;Q8IV36-2;Q8IV36 Q8IV36-3 HID1 Protein HID1 1 T(0.29)GS(0.649)QEGT(0.058)S(0.003)MEGSR;T(0.283)GS(0.716)QEGTSMEGSR 84.62 0.0074827 6679200.0 23052.1 46982.0 19365.7 22012.0 24064.0 11387.7 22766.0 11431.7 10419.2 18262.1 True False 26954.365230271324 51646.06246677894 19827.451732826245 20778.73900386687 19348.831944869395 10790.508965099874 20609.43966843338 11131.629987887367 10571.561088810176 21572.874167295926 1.2494563784705905 2.3940278919845275 0.9190917992227615 0.9631882540420623 0.8969056137267913 0.5001887500673454 0.955340466393528 0.5160012477504138 0.49003952866125117 1.0 14.396930780000934 -5.401678296435091 6.090408371993727 0.7574519963303874 1.8144325973316364 0.6333620599973916 0.318616735852793 0.1279610031284334 5.810949971840916 0.07990094781443369 0.16865201487132866 3.965716858908774e-06 5.401678296435091 1.056980601001249 TGS(ph)QEGTSMEGSR ddPTM_PC-9_Lapatinib_30min_R1 1 TGSQEGTSMEGSR 13 0 Q8IV36-3;Q8IV36-2;Q8IV36 Q8IV36-3 HID1 Protein HID1 1 T(0.024)GS(0.969)QEGT(0.006)S(0.001)MEGSR 75.669 0.01594 1695600.0 3010.9 8964.4 5769.7 5471.5 9101.4 8115.0 11031.0 9813.8 6689.4 7984.9 True False 2967.964013868562 8943.643482571095 5295.337537686069 5873.892362388936 8566.073546040869 7767.940366988939 11602.131204902464 10269.78497503829 5935.969329495144 9365.079325789538 0.31691819264097293 0.9549992233319483 0.5654343496166421 0.6272122379373148 0.9146824333299165 0.8294580426668249 1.2388716423311585 1.0966041629521892 0.6338407954696852 1.0 13.193075499358757 -6.422272660998281 2.0001715945882097 0.9874762899848387 0.6319071323607123 0.38010710560126004 0.20850370026638532 0.36685322716224944 2.9076667592812218 0.07406893233224239 0.08596753118565006 3.7820506351323985e-07 6.422272660998281 -0.35556915762412644 TGS(ph)QGQCTQVR ddPTM_PC-9_AZD4547_30min_R2 1 TGSQGQCTQVR 11 0 P62857 P62857 RPS28 40S ribosomal protein S28 1 T(0.211)GS(0.789)QGQCTQVR 132.06 0.00012744 21976000.0 3428.0 3871.6 3685.3 5971.8 6825.4 4876.1 4315.4 3405.9 3710.0 3105.1 True False 4518.032693170524 5123.018986735548 3636.430514067757 4595.093773390273 5877.811024979904 4571.196696171596 4699.462239962467 2879.596414795949 3906.1030258848873 2996.3913941188825 1.5078246126451362 1.7097295756457813 1.2136033100365662 1.5335425747147775 1.961629924754316 1.5255672890876795 1.5683739611541598 0.9610214541557651 1.30360240439601 1.0 11.54901036822982 -7.750343234367541 24.876092359282968 1.0992339668294053 1.5771111040956862 0.5675978699721824 0.19435247260896327 146.37090787617979 328146.1131801938 0.09468821549027004 0.05400637285930224 1.7768745442090195e-08 7.750343234367541 0.4778771372662809 TGS(ph)QGQCTQVR ddPTM_PC-9_Lapatinib_30min_R1 1 TGSQGQCTQVR 11 0 P62857 P62857 RPS28 40S ribosomal protein S28 1 T(0.01)GS(0.99)QGQCTQVR 112.08 0.0017317 27239000.0 12260.0 6083.8 7666.2 11387.0 10013.0 6829.3 7888.3 6934.3 8174.3 8592.3 True False 12085.17015179135 6069.713334887559 7035.914628387775 12224.437965918456 9424.05502631543 6537.226758875855 8296.71757625167 7256.492892906733 7253.624254804942 10077.46760647992 1.1992268914881408 0.602305417581761 0.6981828077386829 1.2130466148120398 0.9351610339343249 0.6486973726090023 0.8232938968632151 0.7200710710536772 0.719786412425755 1.0 13.298845525274201 -6.7334481685113285 24.95455523572531 0.7674318947308507 0.9142946794810947 0.11724391473971152 0.19767035306108513 496.05956459205055 442242.7397135147 0.0662290518333773 0.06621545396124076 1.8473612576935428e-07 6.7334481685113285 0.14686278475024395 TGS(ph)RDCSTQTER ddPTM_PC-9_AZD4547_30min_R2 2 TGSRDCSTQTER 12 1 E7ERM3;Q4VCS5-2;Q4VCS5 E7ERM3 AMOT Angiomotin 1 T(0.113)GS(0.791)RDCS(0.051)T(0.031)QT(0.014)ER;T(0.236)GS(0.763)RDCSTQT(0.001)ER 98.0 0.018318 4349800.0 15315.1 8274.3 8572.6 13025.300000000001 9701.1 7749.1 7384.0 8406.9 7258.6 8870.6 True False 20184.983226130644 10948.805662244538 8458.921722762665 10022.518323878941 8354.26971817514 7264.547551999202 8041.161695296581 7107.806776343418 7642.2747772744 8560.042994000503 2.3580469444227954 1.2790596577515152 0.9881868267123528 1.1708490635973963 0.975961186647125 0.8486578346733448 0.9393833303094865 0.8303470883645191 0.8927846253378234 1.0 13.063402327442194 -2.485449679576587 1.049068452944436 0.9276338220589556 199.99999999846074 0.9561889797969354 0.09013131111295491 43.53370504783663 0.4633736829787963 0.030187461723841586 20377.002575753875 0.0032700193339095874 2.485449679576587 199.07236617640177 up TGS(ph)RDCSTQTER ddPTM_PC-9_Lapatinib_30min_R1 1 TGSRDCSTQTER 12 1 E7ERM3;Q4VCS5-2;Q4VCS5 E7ERM3 AMOT Angiomotin 1 T(0.016)GS(0.983)RDCS(0.001)T(0.001)QTER 124.3 0.0015753 2246500.0 7159.7 5153.5 6494.9 7492.4 4983.9 5090.2 5000.0 3779.9 4754.3 3850.5 True False 7057.601365071823 5141.567387380098 5960.914393039022 8043.416089913704 4690.7568007244 4872.504011835751 5258.875534812104 3955.52795320337 4218.820669001522 4516.053794531254 1.5627806235652624 1.1385088888016155 1.3199387483509233 1.7810718064638495 1.0386848815673329 1.0789295773527194 1.1644846970557292 0.875881495918703 0.9341829971357585 1.0 12.140846956034567 -6.410741342258362 11.215085322195446 1.0176830747636756 1.4188607019705135 0.6061696030797468 0.1711707310971898 0.40597868388049374 38.34686814281803 0.05466382698590948 0.061974451063520494 3.8838161000784607e-07 6.410741342258362 0.4011776272068379 TGS(ph)SPTQGIVNK ddPTM_PC-9_AZD4547_30min_R2 1 TGSSPTQGIVNK 12 0 E9PFH7;A0A087WYG2;A0A669KB35;Q9UPT6 E9PFH7 MAPK8IP3 C-Jun-amino-terminal kinase-interacting protein 3 1 T(0.142)GS(0.553)S(0.305)PTQGIVNK 205.87 7.7013e-08 18948000.0 59087.0 55300.0 71334.0 70774.0 94194.0 61240.0 58085.0 64920.0 56491.0 71338.0 True False 77875.43691405092 73174.6435495599 70388.06455119242 54458.14774739993 81116.78900679202 57410.65311899845 63254.45247444501 54888.105713189754 59476.99893133777 68840.47833359714 1.1312448547593013 1.0629595453268008 1.022480759214016 0.7910774164510996 1.178329828181968 0.8339665050087189 0.918855504866155 0.7973231308359746 0.8639829410120529 1.0 16.07096950143528 -3.902756105018249 0.4562718312131568 0.8845444694382745 1.6110083357329472 0.3110726485003946 0.10976710185799618 12.390755955461307 1.0844334733610117 0.07103012825448836 5.746601629086792 0.0001250961359064374 3.902756105018249 0.7264638662946727 TGS(ph)TSSKEDDYESDAATIVQK ddPTM_PC-9_AZD4547_30min_R2 1 TGSTSSKEDDYESDAATIVQK 21 1 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 T(0.207)GS(0.615)T(0.137)S(0.032)S(0.01)KEDDYESDAATIVQK 82.859 0.00028009 87721000.0 84106.0 73395.0 68139.0 78447.0 72427.0 65019.0 90258.0 67828.0 67687.0 68046.0 True False 110849.95848652272 97118.49843254872 67235.43233876837 60362.25614406816 62371.761231022276 60953.35165160288 98290.78714708558 57346.74113238188 71264.79663425076 65663.73025159053 1.6881459225938154 1.4790280427328644 1.0239356198795875 0.9192632814613215 0.9498662502426365 0.9282651384266499 1.4968809534652463 0.8733396794951778 1.0852992414716578 1.0 16.00280908898833 -5.135993112669201 3.1056960108677125 1.0341568407704855 1.6605716660965895 0.6418573471028204 0.16707934622182075 0.1640952717252558 2.9039625123700668 0.04487196237152726 0.16074610523643348 7.311506784653178e-06 5.135993112669201 0.6264148253261039 TGS(ph)TSSKEDDYESDAATIVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TGSTSSKEDDYESDAATIVQK 21 1 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 T(0.144)GS(0.425)T(0.125)S(0.125)S(0.125)KEDDY(0.045)ES(0.009)DAAT(0.003)IVQK;T(0.086)GS(0.227)T(0.227)S(0.227)S(0.227)KEDDY(0.005)ESDAATIVQK 55.208999999999996 0.0082904 82802000.0 45571.0 47550.0 33897.0 61572.0 64223.0 68787.0 83641.0 75830.0 74572.0 70766.0 True False 53285.270231722694 52270.44975299773 34705.23303508838 58122.320459117356 51638.96417866304 65179.68862740712 75717.91897159959 73839.54284852647 75662.47442363657 83595.31561665215 0.6374193319165876 0.6252796507485819 0.41515762909776144 0.6952820266347486 0.6177255722732935 0.779705036659056 0.9057674872456204 0.8832976142722723 0.9051042377853602 1.0 16.351134480635835 -6.9313551049630915 1.2849139373353415 0.9316503730572474 0.5766252703351286 0.8206579921216264 0.0721406034949727 0.18158155863554173 0.6192584797485028 0.03827449111830812 0.029559415871804762 1.1712373007340698e-07 6.9313551049630915 -0.35502510272211885 TGS(ph)TSSKEDDYESDAATIVQK ddPTM_PC-9_Lapatinib_30min_R1 1 TGSTSSKEDDYESDAATIVQK 21 1 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 T(0.071)GS(0.208)T(0.208)S(0.208)S(0.208)KEDDY(0.071)ES(0.017)DAAT(0.01)IVQK 50.88399999999999 0.018682 62054000.0 19350.0 14262.0 18748.0 18725.0 18539.0 24430.0 23771.0 21970.0 24106.0 20655.0 True False 19074.065451644597 14228.977215254672 17206.61180937284 20102.098964768855 17448.572469076375 23385.18584911149 25001.746067603715 22990.806405428222 21390.928432566438 24225.18922894251 0.7873649725243954 0.5873628924332577 0.7102777050267836 0.8298015249661008 0.7202656831357205 0.9653252087365558 1.0320557594544373 0.9490454827060945 0.8830035641996182 1.0 14.564220314481476 -6.762207582476917 24.595068383137402 0.9668369983634855 0.7240366610850653 0.7529832142998476 0.06839595798081936 8.67891377788385 277859.8886719548 0.02454700841302003 0.022933001397207747 1.728989745529405e-07 6.762207582476917 -0.2428003372784202 TGS(ph)YGALAEITASK ddPTM_PC-9_AZD4547_30min_R2 1 TGSYGALAEITASK 14 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 T(0.287)GS(0.621)Y(0.087)GALAEIT(0.005)ASK 81.594 0.010236 47653000.0 52982.0 67320.0 82583.0 96660.0 97049.0 83843.0 84672.0 75959.0 92467.0 78798.0 True False 69829.17390593953 89079.8734856487 81487.89546122628 74376.53038211312 83575.42153767898 78600.28395584888 92207.64396860126 64221.281914174084 97354.61684487801 76039.30600424465 0.9183299740010982 1.1714977183073727 1.071654907748336 0.9781326828253969 1.0991081577337602 1.0336796597204776 1.2126313194317433 0.8445800637710863 1.2803196394170602 1.0 16.21445774440278 TGS(ph)YGALAEITASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TGSYGALAEITASK 14 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 T(0.035)GS(0.964)YGALAEITAS(0.001)K;T(0.008)GS(0.992)YGALAEITASK;T(0.073)GS(0.927)YGALAEITASK 166.52 3.3053000000000004e-05 60403500.0 74606.8 89234.4 79924.4 112827.7 105023.4 86544.7 97805.3 76536.4 76347.0 66113.6 True False 87236.25768853171 98093.00150239524 81830.1008109749 106506.3297613389 84444.81868678516 82006.14357876289 88540.47393494801 74527.40059701895 77463.43044066623 78099.47232503022 1.1169890793304789 1.2560008228244748 1.0477676529031943 1.3637266244013344 1.0812469812260346 1.0500217368623708 1.133688503892382 0.954262536971502 0.9918560027945266 1.0 16.253025180456603 -7.135097701501765 0.9927096462818389 0.9844910882320419 1.1869865796626893 0.42607539171649456 0.09085311145578308 0.5145300105081496 1.0155750980274432 0.061117506877649844 0.03886476031758616 7.326596910618344e-08 7.135097701501765 0.20249549143064738 TGS(ph)YGALAEITASK ddPTM_PC-9_Lapatinib_30min_R1 3 TGSYGALAEITASK 14 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 T(0.102)GS(0.874)Y(0.013)GALAEIT(0.011)ASK;T(0.311)GS(0.674)Y(0.01)GALAEIT(0.005)ASK;T(0.033)GS(0.967)YGALAEITASK 89.46600000000001 0.015416999999999998 84336000.0 127955.2 115137.9 116020.6 120169.0 119772.1 105462.6 123109.7 100163.0 108346.1 93304.3 True False 126130.53538389035 114871.30526660122 106481.83412046717 129006.62913203241 112727.34055900872 100952.21044332802 129483.7178856117 104816.93864300907 96143.02128298715 109431.82393483537 1.152594655271384 1.0497065765348568 0.9730426697801834 1.1788767151395876 1.0301147920748883 0.9225123626144 1.183236404455041 0.9578286724474739 0.8785654650171831 1.0 16.739672824600547 -7.975107331336347 24.678553184042006 0.9322541210685189 1.0630561404976706 0.308751230643727 0.08512646156774367 214.31284950527183 212469.1921365304 0.04534569302642039 0.021782036245177085 1.0589919740499706e-08 7.975107331336347 0.1308020194291517 TGSCS(ph)ELDACPSK ddPTM_PC-9_AZD4547_30min_R2 2 TGSCSELDACPSK 13 0 A0A1B0GUA8;Q9H1H9-3;Q9H1H9-4;Q9H1H9-2;Q9H1H9;H0Y9Z7 A0A1B0GUA8 KIF13A Kinesin-like protein KIF13A 1 T(0.03)GS(0.148)CS(0.822)ELDACPSK;T(0.047)GS(0.159)CS(0.794)ELDACPSK 167.73 0.00027872 63930000.0 118466.0 118339.0 106304.0 157608.0 137035.0 136009.0 130962.0 118574.0 129325.0 116926.0 True False 156135.7237541243 156589.76750472627 104894.33950220035 121273.91061932642 118010.05564628035 127504.33572929236 142617.3642929887 100251.11285945418 136160.8554777796 112832.45632950451 1.3837837873365206 1.3878078400370664 0.9296468668188657 1.0748140611702217 1.0458874997957655 1.1300324381571698 1.2639746481854774 0.8884953507232968 1.2067525595662758 1.0 16.783822594038895 -5.244309016094027 24.463289452486 1.0722147994187554 1.3857959245276006 0.5780767992115324 0.10872743478121298 423.53288720031316 604829.6035312229 0.026725602623963663 0.07030624645641628 5.697587242578066e-06 5.244309016094027 0.31358112510884517 TGSCS(ph)ELDACPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGSCSELDACPSK 13 0 A0A1B0GUA8;Q9H1H9-3;Q9H1H9-4;Q9H1H9-2;Q9H1H9;H0Y9Z7 A0A1B0GUA8 KIF13A Kinesin-like protein KIF13A 1 T(0.095)GS(0.18)CS(0.725)ELDACPSK 87.831 0.0069042 28830000.0 37165.0 39859.0 32764.0 50442.0 52956.0 45454.0 45260.0 46021.0 41776.0 33405.0 True False 43456.300457790545 43815.938101045955 33545.218018161926 47615.89827517048 42579.651947826795 43070.312222806126 40972.6451459762 44812.99751328009 42386.89496757279 39461.06206616551 1.1012450801482763 1.1103588146608547 0.850084013499578 1.2066552642534436 1.079029547568493 1.0914635837877065 1.0383056866861864 1.135625732478787 1.0741448087864804 1.0 15.268142165235107 TGSCS(ph)ELDACPSK ddPTM_PC-9_Lapatinib_30min_R1 1 TGSCSELDACPSK 13 0 A0A1B0GUA8;Q9H1H9-3;Q9H1H9-4;Q9H1H9-2;Q9H1H9;H0Y9Z7 A0A1B0GUA8 KIF13A Kinesin-like protein KIF13A 1 T(0.102)GS(0.233)CS(0.665)ELDACPSK 181.76 7.8477e-05 29326000.0 41277.0 47823.0 41262.0 39296.0 48376.0 45030.0 49584.0 43987.0 43675.0 39386.0 True False 40688.382410725266 47712.26878173637 37869.59763592608 42185.958927613174 45530.61879087538 43104.171870056925 52151.21690362471 46030.796602438364 38755.861581860896 46193.817621453876 0.8808187871406473 1.0328713069944944 0.8197979640101934 0.9132382015558003 0.9856431257530339 0.9331156005178922 1.1289652942519308 0.9964709342632941 0.838983733699062 1.0 15.495412160114983 -6.261619193765898 20.02254336388802 0.9854044201355627 0.9137748269461864 0.13944020884758634 0.0831988159870645 2.123930643978723 236414.72131106685 0.025607066592089663 0.030925010712679852 5.47495818038511e-07 6.261619193765898 -0.07162959318937634 TGSDHTNPT(ph)SPLLVKPSDLLEENK ddPTM_PC-9_AZD4547_30min_R2 3 TGSDHTNPTSPLLVKPSDLLEENK 24 1 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;Q96D71;Q96D71-3;H0YE73 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 TGSDHT(0.001)NPT(0.499)S(0.499)PLLVKPS(0.002)DLLEENK;TGSDHT(0.001)NPT(0.499)S(0.499)PLLVKPS(0.001)DLLEENK;T(0.001)GS(0.005)DHT(0.024)NPT(0.485)S(0.485)PLLVKPSDLLEENK 61.345 0.0021654 32655100.0 29165.800000000003 36492.4 77855.0 102149.0 94203.0 96845.0 65490.0 102809.0 77129.0 88758.0 True False 38439.91771367353 48287.85465222347 76822.5918304467 78600.12623631788 81124.53951214315 90789.2668404539 71318.4831290592 86922.23136579379 81205.88147802565 85650.6094358327 0.448799114996044 0.5637771286192602 0.8969298915263444 0.9176832103594446 0.9471565940569242 1.0599955731601765 0.8326675501648266 1.0148466185861031 0.9481062891778146 1.0 16.3861758912052 -5.206406996044553 2.1229664603421563 0.9603185472461443 0.43714722856683336 0.9082261132458558 0.05756834134441998 0.09363300929398638 0.7560024838768029 0.015474013991730439 0.06554845136025732 6.217173739756393e-06 5.206406996044553 -0.523171318679311 down TGSDHTNPT(ph)SPLLVKPSDLLEENK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TGSDHTNPTSPLLVKPSDLLEENK 24 1 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;Q96D71;Q96D71-3;H0YE73 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 T(0.013)GS(0.013)DHT(0.012)NPT(0.48)S(0.48)PLLVKPS(0.001)DLLEENK;TGSDHTNPT(0.5)S(0.5)PLLVKPSDLLEENK;TGSDHT(0.001)NPT(0.499)S(0.499)PLLVKPSDLLEENK;TGSDHTNPT(0.5)S(0.5)PLLVKPSDLLEENK 84.529 1.4458e-05 19007900.0 41721.3 77497.0 119376.0 129835.0 188887.0 152604.0 170618.0 120080.0 151449.0 100187.0 True False 48783.89205676357 85190.3900001695 122222.37657600138 122560.76588074956 151875.94828667463 144601.17759601143 154455.82787265058 116928.0272352767 153663.65511164165 118350.11002014464 0.4121998031810867 0.7198167368468779 1.032718740651763 1.0355779632134539 1.2832767815832489 1.2218085608150135 1.3050754903933786 0.9879841025527912 1.298382021660024 1.0 16.85270152166222 -4.913493369950611 1.1029319880055382 1.1852776971071814 0.13360020391160846 0.8295628362700056 0.11148437829709656 0.5065539142933877 0.5956881855763376 0.03447721515227484 0.5908675862294979 1.220412451727221e-05 4.913493369950611 -1.051677493195573 down TGSDHTNPT(ph)SPLLVKPSDLLEENK ddPTM_PC-9_Lapatinib_30min_R1 1 TGSDHTNPTSPLLVKPSDLLEENK 24 1 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;Q96D71;Q96D71-3;H0YE73 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 TGSDHTNPT(0.5)S(0.5)PLLVKPSDLLEENK 67.76 0.00064784 7684500.0 12890.0 13903.0 29007.0 20403.0 35158.0 44875.0 35018.0 42249.0 48458.0 25659.0 True False 12706.186236263506 13870.808457697774 26622.156430258034 21903.504682412768 33090.07556328749 42955.80085873428 36831.06069561006 44212.04277755739 43000.149754638056 30094.123961531608 0.4222148567110786 0.46091417963946724 0.8846297192198821 0.7278332710535566 1.099552710209658 1.4273816680506586 1.2238621979058129 1.4691254290728744 1.4288553409829714 1.0 14.877194200118257 -5.949666361542219 0.8869844474064915 1.3539925686867866 0.4036520940082125 0.8055600756849016 0.16240175569033366 0.27279579253029146 0.4255477570875756 0.07207132324411528 0.17743405408148516 1.1228807547736057e-06 5.949666361542219 -0.9503404746785742 down TGSDHTNPT(ph)SPLLVKPSDLLEENKINSSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGSDHTNPTSPLLVKPSDLLEENKINSSVK 30 2 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;Q96D71;Q96D71-3;H0YE73 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 T(0.002)GS(0.001)DHT(0.005)NPT(0.474)S(0.474)PLLVKPS(0.043)DLLEENKINS(0.001)S(0.001)VK 46.398999999999994 0.0099029 4532700.0 6274.6 5010.1 8868.4 20611.0 22968.0 26802.0 20713.0 16171.0 28053.0 12523.0 True False 7336.765851001015 5507.469617402602 9079.856289594292 19456.23249176359 18467.585277167556 25396.45593777557 18750.914690866226 15746.528384590778 28463.222053938116 14793.32076798654 0.49595124489412346 0.37229434173569953 0.6137808022958265 1.3152038542872546 1.2483732061791224 1.7167515215876832 1.2675257290063033 1.0644349995213396 1.9240590061113187 1.0 13.85265832094831 -5.723169903913971 3.2043559755558677 1.3810266157467064 0.4392602696860093 0.6984405545014947 0.26324114963876827 0.12658093728688577 2.6558788017464363 0.07248046355089514 0.12928022688725327 1.8916034441380285e-06 5.723169903913971 -0.9417663460606971 TGSDHTNPTS(ph)PLLVKPSDLLEENK ddPTM_PC-9_Lapatinib_30min_R1 1 TGSDHTNPTSPLLVKPSDLLEENK 24 1 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;Q96D71;Q96D71-3;H0YE73 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 1 TGSDHTNPT(0.153)S(0.847)PLLVKPSDLLEENK 89.831 5.8516e-06 8230500.0 21508.0 24857.0 51956.0 31533.0 68427.0 87626.0 60204.0 70365.0 94557.0 46372.0 True False 21201.291975915858 24799.445143709538 47684.378235959826 33852.04201100434 64402.25839265816 83878.44024618274 63321.0685395656 73634.41478006176 83906.99493064728 54387.338413193975 0.3898203625050454 0.455978282211607 0.8767551350590075 0.6224250533060114 1.1841406524323432 1.5422420492236193 1.1642612120214428 1.353888918421472 1.5427670737108925 1.0 15.730983205020976 -6.299757749969511 2.948184730569261 1.3382667995289808 0.581332980421189 0.7680566440391978 0.1925836254395815 0.12616704422004965 2.1977212120057557 0.06274876191482028 0.07632163319812184 5.01466874507008e-07 6.299757749969511 -0.7569338191077918 TGSEES(ph)T(ph)MMSY(ph)FSK ddPTM_PC-9_AZD4547_30min_R2 1 TGSEESTMMSYFSK 14 0 X6RLL4;O75818-2;O75818 X6RLL4 RPP40 Ribonuclease P protein subunit p40 3 T(0.003)GS(0.083)EES(0.914)T(0.745)MMS(0.336)Y(0.79)FS(0.13)K 55.083999999999996 0.037977 0.0 7568.7 7762.2 9374.1 11259.0 6841.5 11470.0 12160.0 11079.0 8592.5 10444.0 True False 9975.389161260135 10271.179351905848 9249.79330907187 8663.41149981598 5891.675817886138 10752.77908678825 13242.21644295861 9366.995120092874 9046.68200806358 10078.358738906196 0.9897831005708737 1.0191321442305177 0.9177876625252726 0.859605390545586 0.5845868330864319 1.0669176763155435 1.313925886745701 0.9294167198010926 0.8976344504527348 1.0 13.298973094574608 TGSEPALS(ph)PAVVR ddPTM_PC-9_AZD4547_30min_R2 4 TGSEPALSPAVVR 13 0 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 T(0.002)GSEPALS(0.998)PAVVR;TGSEPALS(1)PAVVR;TGSEPALS(1)PAVVR;TGSEPALS(1)PAVVR 155.14 7.2312e-05 258693700.0 108989.0 129435.0 177698.0 249746.0 195026.0 210372.0 229997.0 284773.0 240560.0 236712.0 True False 143645.23488796997 171272.33251062 175341.6084141895 192170.91823723615 167950.00629380427 197217.40558376754 250466.28743677214 240767.87628253485 253275.5104870265 228424.7849295254 0.6288513522395918 0.7497974992663852 0.7676120105280461 0.841287508693619 0.7352529908066716 0.8633800646659858 1.0964934803990165 1.0540356921286698 1.1087917213763303 1.0 17.801359671350163 -7.088211669126243 2.9853738556391183 1.0702641907003465 0.7521047372947154 0.875372851865346 0.0568231499668735 0.09069364374067965 1.5644939271697786 0.02406264893178139 0.018402172553024614 8.161844773721517e-08 7.088211669126243 -0.3181594534056311 TGSEPALS(ph)PAVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 TGSEPALSPAVVR 13 0 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 T(0.003)GSEPALS(0.997)PAVVR;TGSEPALS(1)PAVVR;T(0.163)GS(0.036)EPALS(0.801)PAVVR;TGSEPALS(1)PAVVR;TGSEPALS(1)PAVVR;TGS(0.002)EPALS(0.998)PAVVR 137.81 6.13e-05 313096400.0 94271.0 116653.0 170014.0 164425.0 200606.0 153521.0 173247.0 173290.0 149761.0 128463.0 True False 110229.21836287806 128233.53890718038 174067.77854168578 155212.80032304252 161298.69436222024 145470.08850172543 156835.78996033926 168741.32111593243 151950.9713050239 151752.3249874514 0.7263758125089225 0.8450186111994277 1.1470518066598299 1.0228034419629306 1.0629075658350424 0.9586020412784749 1.0334984322204501 1.1119521307491391 1.0013090166334448 1.0 17.21135909452351 -5.06365892406635 4.43459581013775 1.042391381646047 0.7471787905002291 0.7975840795311955 0.05314675749589992 0.07910494340210544 3.045803111485129 0.013542214202415696 0.04305267763263355 8.636565596639783e-06 5.06365892406635 -0.295212591145818 TGSEPALS(ph)PAVVR ddPTM_PC-9_Lapatinib_30min_R1 4 TGSEPALSPAVVR 13 0 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 TGSEPALS(1)PAVVR;TGSEPALS(1)PAVVR;TGSEPALS(1)PAVVR;TGSEPALS(1)PAVVR 148.48 6.3485e-05 244390400.0 185964.0 202518.0 216166.0 183287.0 203925.0 176325.0 161922.0 148339.7 183303.0 153090.0 True False 183312.11925837875 202049.0820136688 198393.6659048906 196766.53740750835 191930.53243197576 168783.99078365078 170305.52886956927 155232.1040026992 162657.48587383743 179551.4025203974 1.020945070242791 1.1252993804418523 1.1049407752877491 1.0958785876660322 1.0689447686724256 0.9400315921479733 0.9485057007573207 0.8645552294422458 0.9059104166861589 1.0 17.454037396731053 -6.760996289085148 3.105136394354246 0.9204852418971758 1.0908189932292043 0.7732111864734297 0.040960928128877416 0.1090106122677772 2.173814070040755 0.01475305118185312 0.013730769568575243 1.7338188126476302e-07 6.760996289085148 0.17033375133202844 TGSEPALS(ph)PAVVRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TGSEPALSPAVVRR 14 1 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 TGSEPALS(1)PAVVRR;T(0.009)GSEPALS(0.991)PAVVRR 95.662 0.0014405 9530900.0 23698.0 20926.0 28565.0 42307.0 32644.0 64896.0 46147.0 70549.0 60938.0 46523.0 True False 27709.603343164807 23003.394984883904 29246.09793336575 39936.67595114462 26247.642536914744 61492.739517121256 41775.62208465234 68697.16350284447 61829.10296663038 54957.25162413465 0.5042028581173816 0.4185688749905006 0.5321608535555339 0.7266861928300341 0.47760107649539024 1.1189194819581647 0.7601475847148522 1.2500108988833767 1.125039938123069 1.0 15.746022237283064 -6.7849286368784245 0.9232775703178261 1.118774524320756 0.47860421524827196 0.7094013665685113 0.15852264964504764 0.28908650976340095 0.5314651517163866 0.0928313946040494 0.08355301349273823 1.64085937650311e-07 6.7849286368784245 -0.6401703090724842 TGSEPALS(ph)PAVVRR ddPTM_PC-9_Lapatinib_30min_R1 2 TGSEPALSPAVVRR 14 1 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 TGSEPALS(1)PAVVRR;TGSEPALS(1)PAVVRR 93.738 0.0016669 14632400.0 241090.0 46092.0 49211.0 45429.0 36917.0 37339.0 25727.0 26917.0 54051.0 30797.0 True False 237652.01238950907 45985.27680588406 45165.0615399534 48770.000206701436 34745.61464161455 35742.098011460264 27059.01817682221 28167.662085339605 47963.20719773703 36120.220415576965 6.579472928327449 1.2731172810355487 1.2504093557656093 1.3502132502400017 0.9619435939718238 0.9895315587843524 0.7491376814841617 0.7798308471338178 1.327876924501068 1.0 15.140519076119316 -4.760840886540334 5.714113256760651 1.0511635431082642 6.8213054389648 0.986093712113745 0.19623165573153004 0.01627662345886779 1.8287264549994828 0.05461097226431815 0.37021715575764946 1.7344393318557193e-05 4.760840886540334 5.770141895856536 up TGSES(ph)PKVCSDQSSGSGTGK ddPTM_PC-9_AZD4547_30min_R2 2 TGSESPKVCSDQSSGSGTGK 20 1 O15169-2;O15169 O15169-2 AXIN1 Axin-1 1 T(0.012)GS(0.009)ES(0.98)PKVCSDQSSGSGTGK;T(0.04)GS(0.013)ES(0.709)PKVCS(0.238)DQSSGSGTGK 134.4 3.1659e-05 17410500.0 51657.0 43953.0 48540.0 82293.0 80865.0 60245.0 53928.0 49494.0 49100.0 70500.0 True False 68082.85146765171 58159.94770223879 47896.32788452745 63321.620264175865 69638.29058150452 56477.870626291005 58727.48752762112 41845.839558974345 51695.32576036331 68031.81645852992 1.0007501638465421 0.8548933532840665 0.7040283558167751 0.9307648033001552 1.0236135709231555 0.8301684941885706 0.8632356239292768 0.6150921985815602 0.7598698440144571 1.0 16.053921989322646 -7.549907683769483 24.982088346017196 0.7603213154483434 0.8849733974717758 0.09919085878313272 0.12243744394509022 390.997606170021 361383.3503693991 0.05746375160845088 0.03317763493432603 2.8189820872614615e-08 7.549907683769483 0.12465208202343248 TGSES(ph)PKVCSDQSSGSGTGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TGSESPKVCSDQSSGSGTGK 20 1 O15169-2;O15169 O15169-2 AXIN1 Axin-1 1 T(0.03)GS(0.079)ES(0.891)PKVCS(0.001)DQSSGSGTGK;T(0.027)GS(0.081)ES(0.798)PKVCS(0.081)DQS(0.01)S(0.002)GS(0.001)GT(0.001)GK;T(0.131)GS(0.052)ES(0.771)PKVCS(0.042)DQS(0.001)S(0.002)GSGTGK 69.704 0.0021335 13168900.0 68676.0 35765.9 41438.8 88508.0 81669.0 80652.0 82606.0 102723.0 76663.0 68505.0 True False 80301.49038717139 39316.50218340149 42426.85814952414 83549.18370680774 65666.54571582204 76422.46714026852 74780.96166435075 100026.63009401539 77784.05134285316 80924.41421471843 0.9923023992994966 0.48584228338165286 0.5242776059762642 1.0324348284452818 0.8114553111448867 0.9443684935116762 0.9240840652356515 1.2360500976703106 0.9611938757624753 1.0 16.30428739682567 -6.410837541627768 0.9258874007210467 1.0500648117870806 0.6733156663150005 0.359468542986363 0.1744359608982164 0.5878841270398375 1.0917744791677162 0.09105093497351481 0.12300969339094589 3.882955901990526e-07 6.410837541627768 -0.37674914547208005 TGSES(ph)PKVCSDQSSGSGTGK ddPTM_PC-9_Lapatinib_30min_R1 1 TGSESPKVCSDQSSGSGTGK 20 1 O15169-2;O15169 O15169-2 AXIN1 Axin-1 1 T(0.066)GS(0.066)ES(0.863)PKVCS(0.006)DQSSGSGTGK 80.835 0.00064198 8852900.0 47851.0 23525.0 27952.0 31045.0 30622.0 27713.0 23058.0 20230.0 28746.0 24620.0 True False 47168.63596520133 23470.529307871693 25653.89445784028 33328.152863084084 28820.874165168378 26527.77959215829 24251.830416339504 21169.959653245915 25508.32277120032 28875.534195912092 1.6335156137779432 0.8128171464683903 0.8884301250943472 1.1542003911325855 0.9981070469424786 0.9186939854402356 0.8398746929424022 0.733145212469972 0.88338877466764 1.0 14.817560016109812 -4.756572479661306 24.99889113973464 0.9130757170275968 1.6335167126147099 0.7920395000555456 0.11055895586690599 72.93885790573617 374607.79461370164 0.030444584989285248 0.24376900549964292 1.7515700892528963e-05 4.756572479661306 0.720440995587113 TGSES(ph)SQTGTSTTSSR ddPTM_PC-9_AZD4547_30min_R2 2 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 T(0.001)GS(0.332)ES(0.619)S(0.046)QT(0.001)GTSTTSSR;T(0.026)GS(0.123)ES(0.425)S(0.425)QT(0.001)GTSTTSSR 293.77 1.4316999999999996e-111 824147000.0 51245.3 51687.4 42848.8 57775.3 57951.8 58926.7 49087.2 50696.8 52929.5 64861.9 True False 67540.2394315436 68394.34124780311 42280.59691509143 44456.09720448692 49906.192890882674 55242.00413369183 53455.86570549325 42862.774456568666 55727.24531228411 62591.10462342584 1.0790708973406655 1.0927166353636344 0.6755048847511019 0.7102622245118267 0.79733682910917 0.8825855441607995 0.8540489263946691 0.6848061671774124 0.890338102316015 1.0 15.933670017097834 -5.246012444624704 24.79850579835041 0.8004888491373552 1.0858938398199052 0.5570093968565393 0.09733113889847417 499.0462321501481 802203.8613727537 0.024342349882838593 0.06387357357525952 5.675283427602304e-06 5.246012444624704 0.28540499068255 TGSES(ph)SQTGTSTTSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 T(0.003)GS(0.054)ES(0.609)S(0.334)QTGTSTTSSR;T(0.003)GS(0.078)ES(0.906)S(0.012)QT(0.001)GTSTTSSR 260.07 8.882e-58 55534800.0 8425.699999999999 8709.4 8687.4 11188.3 12870.4 9546.8 12301.599999999999 11246.6 9387.900000000001 10544.3 True False 9852.004594839389 9574.011673580617 8894.540563147964 10561.455823958013 10348.537510939459 9046.149001819107 11136.30339212861 10951.388666757692 9525.1802773381 12455.89812136713 0.7909509614516705 0.7686327858733157 0.714082635911261 0.8479080128184937 0.8308142383717271 0.7262542543039219 0.8940586446372054 0.8792130892570027 0.7647124426137036 1.0 13.60454142911119 -14.522878745255031 0.1424236973983163 1.6873017916590947 0.7352064366582294 0.5471570693999575 0.055819198120708804 105.02434854326494 0.9064328375612372 20.424139645056357 0.32814332280000386 3.0000000001748087e-15 14.522878745255031 -0.9520953550008653 TGSES(ph)SQTGTSTTSSR ddPTM_PC-9_Lapatinib_30min_R1 3 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 TGS(0.002)ES(0.499)S(0.499)QTGTSTTSSR;T(0.014)GS(0.052)ES(0.705)S(0.229)QTGTSTTSSR;T(0.12)GS(0.339)ES(0.414)S(0.124)QT(0.001)GTSTTSSR 316.8 4.708799999999997e-304 25366500.0 6981.7 9817.679999999998 10352.18 8120.8 10250.08 11026.07 12992.64 11256.680000000002 11087.199999999999 11301.49 True False 6882.139677713028 9794.947765156465 9501.063720970405 8718.030722194659 9647.190446832632 10554.510689124549 13665.33532572423 11779.706447330715 9838.442782608096 13254.937488211152 0.5192132881678209 0.7389659720287646 0.7167943062289494 0.6577194898088666 0.7278186302585565 0.79627012187056 1.030961884043443 0.8887032819134382 0.742247392064907 1.0 13.694242245857192 -6.854340233507244 2.5886164001935144 0.9067059733773517 0.6724359676321628 0.6063069053886965 0.09226224026833525 0.20526443681006615 2.798775995850763 0.03592201433959985 0.031475335948509924 1.3984912920086078e-07 6.854340233507244 -0.23427000574518886 TGSESS(ph)QTGTSTTSSR ddPTM_PC-9_AZD4547_30min_R2 1 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 T(0.005)GS(0.005)ES(0.252)S(0.723)QT(0.016)GTSTTSSR 72.428 0.016288999999999998 1440400.0 1328.5 657.77 2525.9 3560.8 2961.0 2586.7 616.13 2295.1 2509.8 2853.1 True False 1750.9353654833837 870.381289106582 2492.4049156062583 2739.9125738115936 2549.9162605804054 2424.953240086763 670.9643763980338 1940.4450311512921 2642.462904141748 2753.213837416052 0.6359605424352628 0.3161328325748402 0.9052710987190998 0.9951688229138999 0.9261599029930616 0.880771848205816 0.24370223891789958 0.7047927061751368 0.9597739442649882 1.0 11.426900950606809 -14.522878745271797 0.035119274879908485 2.1222428256160097 1.2489386121748806e-14 0.11136350655215699 0.24905606892257207 3247.7416375802404 8.52290734865968 433.033190952011 150.1009256307648 3.0000000000589984e-15 14.522878745271797 -2.1222428256159973 TGSESSQTGTSTT(ph)SSR ddPTM_PC-9_AZD4547_30min_R2 2 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 TGSESSQT(0.001)GT(0.001)ST(0.006)T(0.969)S(0.017)S(0.006)R;TGSESS(0.002)QT(0.004)GTS(0.002)T(0.014)T(0.966)S(0.007)S(0.004)R 175.19 2.8728000000000003e-05 6339300.0 9819.4 12028.1 14119.5 21061.7 19111.9 16878.4 12044.900000000001 15888.8 14358.9 15806.2 True False 12941.764943791897 15915.948102684632 13932.266204482581 16206.250465021232 16458.542580407517 15822.990979812272 13116.87276593687 13433.551048301442 15117.882139724661 15252.829749032851 0.8484828819788345 1.0434751036078291 0.9134217344401944 1.0625077924343078 1.0790484684621302 1.0373806854308836 0.8599632318566057 0.88072516833496 0.9911526181352187 1.0 13.89678930000713 -9.719699629379466 9.251003358437744 0.9999999997224321 0.9713233893708623 0.011776847044961847 0.08302616262795832 0.0 0.0 0.08422196319080527 0.020426826484268988 1.9067790455329652e-10 9.719699629379466 -0.028676610351569876 TGSESSQTGTSTT(ph)SSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 TGSESSQTGTS(0.003)T(0.013)T(0.823)S(0.155)S(0.006)R;TGSESSQTGTS(0.001)T(0.006)T(0.986)S(0.003)S(0.003)R 158.64 9.955299999999999e-05 4926500.0 9032.400000000001 12279.4 10281.9 14558.7 14070.4 12181.599999999999 12271.2 9780.0 11632.0 8090.099999999999 True False 10561.40692196818 13498.417680272549 10527.059490322887 13743.02323894224 11313.406125211535 11542.775451518803 11108.783100205548 9523.285362766555 11802.095994418001 9556.771088803638 1.1051229357519652 1.4124454331742653 1.101528894278529 1.4380404334517398 1.1838105171804216 1.2078112308289872 1.1623992033481048 0.9964961255505729 1.2349459754503174 1.0 13.22230754711194 -7.210345705904059 1.548980236433295 1.0853940349727793 1.2606068200473393 0.2649401713331373 0.12197051488893468 0.5160084335412666 2.428355147386042 0.06337407333478164 0.039677200626171125 6.161043768956798e-08 7.210345705904059 0.17521278507455995 TGSESSQTGTSTT(ph)SSR ddPTM_PC-9_Lapatinib_30min_R1 2 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 TGSESSQTGTST(0.003)T(0.985)S(0.012)S(0.001)R;TGSESSQT(0.001)GT(0.001)S(0.003)T(0.03)T(0.949)S(0.014)S(0.002)R 192.24 1.7733e-08 5907600.0 18508.6 19688.0 23626.0 19854.7 20042.9 15878.3 12828.900000000001 15472.800000000001 17611.9 14613.4 True False 18244.663969938454 19642.413645627123 21683.561478997366 21314.880871337584 18864.01602785754 15199.222123125131 13493.117669710213 16191.722774233493 15628.26236047113 17139.306718868484 1.0644925299022214 1.1460448177873492 1.2651364395694116 1.2436256157241328 1.1006288840779272 0.8868049549747813 0.7872615789561535 0.9447128194752589 0.9118374865925084 1.0 14.065021133487674 -6.655682420506367 3.803357308117818 0.8947093099038763 1.182474345877007 0.7655266388119935 0.0721278653183874 0.10972353174704931 3.001034499658175 0.02617403915037581 0.025875394167135687 2.2096199353771985e-07 6.655682420506367 0.28776503597313075 TGSESSQTGTSTTSSR ddPTM_PC-9_Lapatinib_30min_R1 4 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 ;;; 174.46 6.9127e-21 3298000.0 1194.17 865.32 1528.5700000000002 3547.12 1368.42 482.04 480.15 1404.41 1280.12 1487.99 False True 1177.1409168160428 863.3164047051029 1402.8968750508345 3807.9870376454433 1287.9322260172328 461.424272890123 505.0098176080068 1469.6640156507708 1135.9394053387928 1745.1870888779556 0.6745070051904117 0.494684157479162 0.8038661780112114 2.1819935879159735 0.7379909204148946 0.26439817016225436 0.28937288204022643 0.8421240479126346 0.6508983550119716 1.0 10.769165990282257 -6.512444351119461 24.983915484896475 0.5707925168621438 1.0427304375247386 0.15403824480423078 0.47204355696145606 959.7501010256658 2298013.233433906 0.16161456545737313 0.17180599356291976 3.072951096571927e-07 6.512444351119461 0.47193792066259477 TGSGGVASSSESNR ddPTM_PC-9_Lapatinib_30min_R1 1 TGSGGVASSSESNR 14 0 Q15428;K7EMT0 Q15428 SF3A2 Splicing factor 3A subunit 2 0 150.09 0.0010614 1285000.0 2534.5 2942.6 1996.9 824.91 2535.5 734.48 2418.8 2125.1 1220.1 500.63 False True 2498.357565229624 2935.7865904928053 1832.7225902569126 885.5766332190914 2386.3668749847952 703.0680025565047 2544.0336287207037 2223.8399040589647 1082.6794897774132 587.163228452456 4.254962579680553 4.999949670265367 3.121317040045726 1.508229041442432 4.064230795369069 1.1973978759016135 4.3327536627690915 3.7874304729882016 1.8439156904136416 1.0 9.197617810901345 -5.364467605171107 4.92901582093677 2.7072764907387117 4.614971786583304 0.32993180801951316 1.1555681441212597 0.24870665163007039 9.330871799480743 0.29444431502793306 0.638887117095859 4.320483937052443e-06 5.364467605171107 1.9076952958445923 TGSGQGPSST(ph)GQPGR ddPTM_PC-9_AZD4547_30min_R2 1 TGSGQGPSSTGQPGR 15 0 Q8IVF2-3;Q8IVF2 Q8IVF2-3 AHNAK2 Protein AHNAK2 1 TGS(0.002)GQGPS(0.313)S(0.031)T(0.654)GQPGR 116.87 0.00033606 1550500.0 1836.6 1069.4 1147.9 2604.5 2905.9 2039.7 3158.8 3468.6 3818.2 2596.6 True False 2420.600596346843 1415.062636743206 1132.6780959754644 2004.072764123875 2502.4659444851754 1912.1572365581505 3439.927080593561 2932.607570498615 4020.02225699021 2505.6938243435284 0.9660400535891573 0.5647388451835056 0.45204169997594057 0.7998075202380027 0.9987117820114361 0.763124855072475 1.37284413888628 1.1703774587331852 1.6043549367183452 1.0 11.290994424346867 -7.006911360597237 1.179174410593992 1.3237401273647824 0.6808685643022424 0.5670065102379599 0.21931548625824213 0.32810477794737186 0.9341683481823588 0.1256580991977906 0.08989456612322144 9.842119626957211e-08 7.006911360597237 -0.64287156306254 TGSGS(ph)PFAGNS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 1 TGSGSPFAGNSPAR 14 0 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 2 T(0.005)GS(0.023)GS(0.973)PFAGNS(1)PAR 111.73 0.004506100000000001 11503000.0 36643.0 45859.0 44393.0 36799.0 39307.0 34137.0 35066.0 37747.0 33893.0 33043.0 True False 36120.46410049678 45752.81630306858 40743.17890193555 39505.32121786537 36995.03954053534 32677.04008723371 36881.54590074427 39500.863422198374 30075.613430887526 38754.438522970086 0.9320342514854878 1.1805826131618575 1.0513164544439657 1.0193753986256369 0.9546013553675424 0.8431818736805011 0.9516728226854393 1.0192603719129067 0.776055971319555 1.0 15.242073930410466 -6.179045767902369 2.3860226774253803 0.9200740516656881 1.0651334740444633 0.327256441736711 0.08694010856578878 0.33053722473157576 3.6888466722532174 0.027324057555315064 0.036877263477865296 6.621467200305502e-07 6.179045767902369 0.14505942237877523 TGSGS(ph)PFAGNSPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TGSGSPFAGNSPAR 14 0 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 TGS(0.009)GS(0.521)PFAGNS(0.47)PAR;T(0.011)GS(0.003)GS(0.899)PFAGNS(0.087)PAR;T(0.075)GS(0.089)GS(0.836)PFAGNSPAR 137.17 6.692e-05 49262000.0 103282.0 108620.0 146932.0 133776.0 149174.0 121228.0 106089.0 98942.0 113875.0 108850.0 True False 120765.60268751568 119403.07575542817 150435.4161227133 126280.9644276439 119944.42555451917 114870.59027030288 96039.48190215361 96344.87733771456 115540.20644466561 128583.64334387386 0.9391987934620095 0.9286023684684847 1.1699420875826392 0.982091976426023 0.9328124669305671 0.893353052402646 0.7469027895353164 0.7492778617266077 0.8985606834585802 1.0 16.972347608801726 -6.6560663118164385 2.046909028358896 0.8294757868503362 1.0093174729047563 0.3489219056757933 0.09321132959720299 0.32059816463572904 2.752231770706988 0.03640122099565323 0.035940195356592215 2.2076676216045662e-07 6.6560663118164385 0.17984168605442008 TGSGS(ph)PFAGNSPAR ddPTM_PC-9_Lapatinib_30min_R1 3 TGSGSPFAGNSPAR 14 0 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 T(0.001)GS(0.001)GS(0.997)PFAGNSPAR;T(0.005)GS(0.003)GS(0.992)PFAGNSPAR;T(0.041)GS(0.045)GS(0.913)PFAGNS(0.001)PAR 151.38 0.00014608 50635000.0 104520.0 104569.0 130113.0 91454.0 98733.0 97094.0 85007.0 86690.0 104750.0 60548.0 True False 103029.52563337969 104326.87690520017 119415.61139070442 98179.83224160051 92925.71905654666 92941.51595716873 89408.24651755457 90717.93387740405 92951.9519335989 71013.64112486131 1.4508413313468285 1.4691103744668594 1.6815869387789772 1.3825489115390328 1.308561532468923 1.308783981288218 1.2590291822996447 1.2774719397629144 1.3089309386370438 1.0 16.115808560404638 -7.520306435620274 0.11547197770800027 0.7057967721806357 1.9034629412449793 0.7302839766163182 0.08631422563846884 5.115923345688454 0.4782094128516358 2.0137836601272103 2.502154506969928 3.0178216118967395e-08 7.520306435620274 1.1976661690643435 TGSGSPFAGNS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 4 TGSGSPFAGNSPAR 14 0 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 TGSGSPFAGNS(1)PAR;TGSGSPFAGNS(1)PAR;TGSGSPFAGNS(1)PAR;TGSGSPFAGNS(1)PAR 155.26 5.0226e-05 172998700.0 95106.0 100098.0 120113.0 127167.0 121170.0 130612.0 123962.0 150620.0 120088.0 129741.0 True False 125347.72967230929 132452.72097692298 118520.22313956001 97850.61286056472 104347.63704644654 122444.81099246602 134994.3778537861 127345.13990327549 126435.60651548894 125198.80708008698 1.001189488907247 1.0579391614506026 0.946656169525203 0.7815618626299834 0.8334555215026739 0.9780030165474398 1.078240128657401 1.0171433967562928 1.0098786838648615 1.0 16.933861290478575 -6.998270022570604 24.96277463800072 1.0277980913499771 0.9230011115977613 0.2908672259522429 0.07527050946823287 81.55212409068854 1176737.4725785668 0.030776423602430488 0.02694994404441174 1.0039913646036255e-07 6.998270022570604 -0.1047969797522158 TGSGSPFAGNS(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TGSGSPFAGNSPAR 14 0 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 TGSGSPFAGNS(1)PAR;TGSGSPFAGNS(1)PAR;TGSGSPFAGNS(1)PAR;TGSGSPFAGNS(1)PAR 152.94 9.588799999999999e-05 75845400.0 73933.0 100150.0 86374.0 97089.0 110157.0 100839.0 114197.0 99063.0 97258.0 94841.0 True False 86448.39665668843 110092.23013170784 88433.48373521894 91649.41809678487 88572.5266186409 95550.82532308587 103379.43344531687 96462.7012159245 98680.21425594101 112034.92253905686 0.7716200868220476 0.982659938853693 0.7893385538280695 0.818043303103411 0.7905796211691345 0.8528664380499356 0.9227429367773913 0.8610056492188525 0.8807987011508825 1.0 16.77358898101157 -9.174725910846117 0.49026668683262026 1.0101589456252213 0.8383848350939788 0.38733799939223446 0.0595927653011515 2.7394373050135603 1.070793176895668 0.1226130857223262 0.03194281584313918 6.687658516345493e-10 9.174725910846117 -0.17177411053124259 TGSGSPFAGNS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 4 TGSGSPFAGNSPAR 14 0 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 TGSGSPFAGNS(1)PAR;TGSGSPFAGNS(1)PAR;TGSGSPFAGNS(1)PAR;TGSGSPFAGNS(1)PAR 185.74 5.6102999999999995e-06 143004300.0 72019.0 74418.0 83070.0 81093.0 115977.0 115792.0 120430.0 117777.0 117373.0 122218.0 True False 70991.99585333274 74245.68969322839 76240.30525947321 87056.84973831804 109155.46087955503 110839.84608433548 126665.27613148426 123249.34938607727 104153.21674751611 143343.21845475154 0.49525883832266854 0.517957462470854 0.5318724253672288 0.6073314850663748 0.7614972096779843 0.7732479239631679 0.8836502870309703 0.8598198834567315 0.726600238715818 1.0 17.129114126952963 -6.261461798439988 1.1036717222446595 0.8567052745031638 0.49487354116645327 0.8463937012856775 0.0642287148082946 0.18261452384457405 0.46273072663732595 0.026795713292183453 0.04026105436702766 5.476942753145913e-07 6.261461798439988 -0.36183173333671054 TGSGSPFAGNS(ph)PAREGEQDAASLK ddPTM_PC-9_AZD4547_30min_R2 1 TGSGSPFAGNSPAREGEQDAASLK 24 1 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 T(0.003)GS(0.007)GS(0.062)PFAGNS(0.926)PAREGEQDAAS(0.001)LK 49.888000000000005 0.014147 19033000.0 12524.0 8443.2 14959.0 17548.0 20820.0 19859.0 15726.0 14602.0 15733.0 15784.0 True False 16506.371484617168 11172.29928422502 14760.63388596303 13502.57971389739 17929.502379359703 18617.21359063015 17125.583534701247 12345.596420579124 16564.61426044392 15231.406964275691 1.0837062868408562 0.7335040886524106 0.9690919506374671 0.8864958927016292 1.177140261658836 1.2222911274247779 1.1243599212382827 0.8105355237067032 1.0875301473655836 1.0 13.894761592985324 -6.241350242113382 24.685060389049667 1.0711378792552122 0.9086421751252654 0.23901173932126996 0.13252347898673364 1042.73733071674 1281291.1001908844 0.040726054756635724 0.05250204886451946 5.736536455895771e-07 6.241350242113382 -0.16249570412994685 TGSGSPFAGNS(ph)PAREGEQDAASLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGSGSPFAGNSPAREGEQDAASLK 24 1 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 T(0.002)GS(0.002)GS(0.007)PFAGNS(0.988)PAREGEQDAAS(0.001)LK 46.368 0.022397 3721000.0 1877.2 4668.6 5435.5 6305.4 7562.2 5135.1 9189.1 8078.4 8249.0 5445.0 True False 2194.9728836099675 5132.067754297478 5565.102934248542 5952.128880382617 6080.4411957069215 4865.806316173096 8318.641924677204 7866.350559772317 8369.626019425217 6432.135397403713 0.34125103841812054 0.7978793102472628 0.8652030143045274 0.9253736920378189 0.9453223261067001 0.7564838137793469 1.2932939701541368 1.2229765192672273 1.3012204349435117 1.0 12.651082060443066 -4.796561636233463 0.4221647129135134 1.191206237652022 1.014192170393023e-12 0.6687299707204404 0.1583519937223732 3.5135914271967863 0.49605604207358456 0.13065892634017534 2.125031470996324 1.597490792807128e-05 4.796561636233463 -1.1912062376510077 TGSGSPFAGNS(ph)PAREGEQDAASLK ddPTM_PC-9_Lapatinib_30min_R1 1 TGSGSPFAGNSPAREGEQDAASLK 24 1 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 T(0.001)GS(0.001)GS(0.022)PFAGNS(0.964)PAREGEQDAAS(0.013)LK 58.758 0.0025313 14316000.0 37727.0 44543.0 45680.0 44898.0 65562.0 67578.0 59832.0 67899.0 82081.0 62855.0 True False 37189.00606171555 44439.86342021378 41924.36672989925 48199.948695337385 61705.77205985134 64687.84647201219 62929.8081997756 71053.83541748612 72836.17342875166 73719.40300097706 0.5044669998375143 0.6028245158147141 0.5687019295224568 0.6538298837647742 0.8370356995299257 0.8774873891905342 0.853639688304876 0.9638417095773874 0.9880190352027987 1.0 16.16975676724329 -6.306996309388641 0.6523521542761564 0.9876816836448209 0.49397856264102363 0.9553461182561495 0.03728229156148544 0.17400838751049633 0.15886082882985594 0.026540176128176086 0.04745968101321027 4.93177994937443e-07 6.306996309388641 -0.49370312100379726 TGSGSPFAGNS(ph)PAREGEQDAASLKDVFK ddPTM_PC-9_AZD4547_30min_R2 1 TGSGSPFAGNSPAREGEQDAASLKDVFK 28 2 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 T(0.002)GS(0.001)GS(0.004)PFAGNS(0.993)PAREGEQDAAS(0.001)LKDVFK 64.707 0.00090915 6709800.0 9589.9 4004.8 15185.0 20049.0 16195.0 11113.0 9314.5 14713.0 11874.0 13791.0 True False 12639.288717688443 5299.273281867583 14983.636978297265 15427.012803962205 13946.603796048526 10418.102353223878 10143.472455422534 12439.44392110537 12501.635398748549 13308.181287653706 0.949738243302576 0.3981966556755457 1.1258966687054313 1.1592127031117456 1.047972183020012 0.7828344180199124 0.7621982475421234 0.9347215560285249 0.9393947323475818 1.0 13.700025803799726 -5.275706616293693 24.99739147526738 0.9622725183661471 0.6739674055149971 0.31657044437094584 0.17318644087119575 865.5175820540491 1516459.167527892 0.04708289053939332 0.09873145802272816 5.300213741216718e-06 5.275706616293693 -0.28830511285115 TGSGSPFAGNS(ph)PAREGEQDAASLKDVFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGSGSPFAGNSPAREGEQDAASLKDVFK 28 2 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 T(0.011)GS(0.028)GS(0.077)PFAGNS(0.883)PAREGEQDAAS(0.001)LKDVFK 50.158 0.046155 2971100.0 1583.2 1165.3 2466.1 5053.1 4457.8 4345.0 5624.9 5349.0 5581.5 3668.3 True False 1851.2044903746535 1280.9832828005933 2524.9011767363313 4769.991189371235 3584.3260905850548 4117.140551064652 5092.068751250587 5208.5944177339725 5663.118878339418 4333.333751753178 0.4272009949904491 0.295611498256356 0.5826694460621243 1.1007670912588707 0.8271520948818931 0.9501092661969416 1.1750926752850368 1.2019832111077717 1.3068734611194526 1.0 12.081261641386378 -5.59439612384047 0.7215768721629134 1.16567916593767 0.16631565720260927 0.8067250112672855 0.1443640700174253 0.5156405669481207 0.41172356960304723 0.07383676046441212 0.3559458007515146 2.5445083252583014e-06 5.59439612384047 -0.9993635087350607 down TGSGSPFAGNSPAREGEQDAAS(ph)LK ddPTM_PC-9_Lapatinib_30min_R1 1 TGSGSPFAGNSPAREGEQDAASLK 24 1 Q9UPT8;M0QY97 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 T(0.001)GS(0.001)GS(0.004)PFAGNS(0.201)PAREGEQDAAS(0.793)LK 49.577 0.014875 17471000.0 22504.0 22961.0 27689.0 26191.0 32490.0 37532.0 33308.0 30717.0 40335.0 33268.0 True False 22183.088833271828 22907.835215219624 25412.517302630917 28117.173510614735 30579.002077797682 35926.84385136523 35032.52526270433 32144.223957921648 35792.04755362018 39018.329473176454 0.568529948175301 0.587104458968902 0.6512969070113832 0.7206144878638172 0.7837086438777325 0.9207683756954151 0.8978479021452672 0.8238236847125789 0.9173136840270362 1.0 15.2518643914186 -6.053516600727007 0.8438780023844705 0.9133882739139241 0.5507128549940713 0.9110023355406232 0.04265192477800917 0.19748254215609104 0.28728622504896784 0.021214082995062195 0.0464726626681771 8.840633755976199e-07 6.053516600727007 -0.3626754189198528 TGSIVLPY(ph)IMSSTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGSIVLPYIMSSTLR 15 0 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 T(0.005)GS(0.025)IVLPY(0.487)IMS(0.221)S(0.221)T(0.042)LR 73.84100000000001 0.017588999999999997 8850200.0 50083.0 41163.0 26319.0 41234.0 39194.0 38624.0 25970.0 41317.0 27797.0 23279.0 True False 58561.06271566057 45249.390603210166 26946.54477536332 38923.792662431704 31514.21705648319 36598.489446333995 23509.933593482157 40232.47252898011 28203.47853824254 27499.29842353739 2.129547518402745 1.6454743647016097 0.9798993545340431 1.415446752965733 1.1460007659507896 1.3308881151312704 0.8549284869522115 1.4630363258483734 1.0256072029133085 1.0 14.74710719186694 -4.9663975015147335 2.9314747837398802 1.1741518829806579 2.142268716180788 0.7230088510974964 0.19250739753818671 0.14188444508529469 2.2321049592945728 0.046490226265685886 0.26679720225721365 1.080444588123979e-05 4.9663975015147335 0.9681168332001302 TGSNIS(ph)GASSDISLDEQYK ddPTM_PC-9_AZD4547_30min_R2 2 TGSNISGASSDISLDEQYK 19 0 P22059 P22059 OSBP Oxysterol-binding protein 1 1 T(0.237)GS(0.237)NIS(0.525)GAS(0.001)SDISLDEQYK;TGS(0.012)NIS(0.862)GAS(0.12)S(0.006)DISLDEQYK 154.56 2.0022999999999998e-05 21982500.0 35350.0 50653.0 51401.0 49003.0 51857.0 55755.0 64699.0 62995.0 60603.0 56193.0 True False 46590.56467432261 67025.59167659782 50719.38915518321 37706.11543880292 44657.55066697674 52268.631036083585 70457.08566142913 53260.5702310904 63806.35085652337 54225.70017381805 0.8591971062610284 1.236048432048831 0.9353385754836634 0.6953550681307509 0.8235495442904189 0.9639088267839573 1.2993301227200773 0.9822016140015903 1.1766809953950799 1.0 15.726689155953656 -7.020463876071015 24.094531446202478 1.1157199471946309 0.915133318140825 0.28881864839858495 0.15226978912727715 690.5817186083356 813101.0559467602 0.06080773812896777 0.047738372011250474 9.539730895162055e-08 7.020463876071015 -0.20058662905380586 TGSNIS(ph)GASSDISLDEQYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TGSNISGASSDISLDEQYK 19 0 P22059 P22059 OSBP Oxysterol-binding protein 1 1 T(0.004)GS(0.015)NIS(0.921)GAS(0.046)S(0.014)DIS(0.001)LDEQYK;T(0.001)GS(0.001)NIS(0.967)GAS(0.028)S(0.003)DISLDEQYK;T(0.001)GS(0.004)NIS(0.986)GAS(0.009)SDISLDEQYK;T(0.018)GS(0.295)NIS(0.685)GAS(0.002)SDISLDEQYK 192.22 8.2321e-12 26169400.0 90907.2 115065.0 83713.9 132101.1 130593.0 86788.1 146071.0 102672.1 86178.4 87322.8 True False 106295.99346095668 126487.89276190702 85709.95686273373 124699.9036445447 105004.23911969436 82236.77925428178 132234.09741754064 99977.06616508221 87438.59606648501 103153.73239309537 1.0304619231409569 1.226207620679109 0.830895352735397 1.2088743737293166 1.017939309452683 0.7972254357301988 1.2819128726590971 0.9692045439916066 0.8476532456748772 1.0 16.65443649738289 -4.89180520951498 0.2822475708545616 0.9665087301980289 1.1899855781661781 0.05027123726935678 0.15863440154368136 28.61454552602602 1.988997254893125 0.19754529370330567 2.216966478284578 1.28290586471027e-05 4.89180520951498 0.22347684796814926 TGSNIS(ph)GASSDISLDEQYK ddPTM_PC-9_Lapatinib_30min_R1 3 TGSNISGASSDISLDEQYK 19 0 P22059 P22059 OSBP Oxysterol-binding protein 1 1 TGSNIS(0.985)GAS(0.014)S(0.001)DISLDEQYK;T(0.001)GS(0.001)NIS(0.997)GASSDISLDEQYK;TGSNIS(0.999)GASSDISLDEQYK 196.89 7.5318e-15 26297300.0 55224.8 100687.0 114868.0 120626.0 150918.0 138766.0 130844.0 145287.0 126875.0 121292.0 True False 54437.28422501202 100453.86543769065 105423.99644330249 129497.23843654002 142041.2999562039 132831.3016593453 137618.46209539115 152037.56441627012 112585.0014470201 142257.16058856907 0.3826681483011849 0.7061427700516224 0.7410804208879572 0.9103038321639723 0.9984826026930942 0.9337407066876241 0.96739216167407 1.0687515748749379 0.7914188711571033 1.0 17.118141747605698 -4.66434336259157 0.835283899567354 0.9672514855646244 6.532250260414935e-18 0.8443724427226117 0.07600778117685776 1.0142450173331543 0.47875898068834766 0.02681787523925044 0.9504657021925389 2.1659909484833047e-05 4.66434336259157 -0.9672514855646244 down TGSNISGAS(ph)SDISLDEQYK ddPTM_PC-9_AZD4547_30min_R2 1 TGSNISGASSDISLDEQYK 19 0 P22059 P22059 OSBP Oxysterol-binding protein 1 1 TGSNIS(0.209)GAS(0.789)S(0.002)DISLDEQYK 190.1 2.8718000000000004e-11 6206200.0 33243.0 28829.0 31425.0 29296.0 25447.0 30955.0 31428.0 29053.0 29446.0 20854.0 True False 43813.58250264521 38147.41046817832 31008.283967269774 22542.259818688053 21914.12329719337 29019.378956541415 34225.03111589668 24563.526421523457 31002.455444799572 20123.90780746358 2.1771905795749853 1.8956263779955382 1.5408679200850535 1.1201730814095436 1.088959634821316 1.4420349782053101 1.7007149626874785 1.22061413998395 1.5405782883432484 1.0 14.296622864962318 -5.214448227884608 2.2109329789933287 1.3254123565365614 2.1486769345990506 0.6660830602540553 0.20801862986516972 0.2160892782792076 1.9227960456492916 0.059531891920136346 0.23912490830796382 6.103118073964378e-06 5.214448227884608 0.8232645780624892 TGSPGS(ph)PGAGGVQSTAK ddPTM_PC-9_AZD4547_30min_R2 4 TGSPGSPGAGGVQSTAK 17 0 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 T(0.063)GS(0.003)PGS(0.934)PGAGGVQSTAK;T(0.004)GS(0.001)PGS(0.995)PGAGGVQSTAK;T(0.016)GS(0.083)PGS(0.859)PGAGGVQS(0.016)T(0.026)AK;TGS(0.012)PGS(0.988)PGAGGVQSTAK 221.81 3.5829e-23 30775900.0 75552.0 70073.8 94717.0 109120.0 99899.0 88136.0 81559.0 132359.0 92304.0 93850.0 True False 99575.9644207758 92723.78548215459 93460.99069301152 83964.06988719419 86029.74823225985 82624.84198719854 88817.59299928157 111905.95785724111 97183.00099764921 90564.34006571691 1.0995052174897946 1.0238443234375771 1.0319844502283426 0.9271206506475582 0.9499296099307234 0.9123330653902278 0.9807126395977949 1.2356514470931705 1.0730824177278777 1.0 16.466655476867366 -7.713090126784129 24.99434339158707 1.1157755079164478 0.9854422204435164 0.31996952013170266 0.07501871050613781 114.5694221385949 59226.92368014729 0.035877603059758026 0.020713880212942817 1.9360201504677477e-08 7.713090126784129 -0.13033328747293138 TGSPGS(ph)PGAGGVQSTAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TGSPGSPGAGGVQSTAK 17 0 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 T(0.001)GS(0.002)PGS(0.997)PGAGGVQSTAK;T(0.009)GSPGS(0.991)PGAGGVQSTAK;TGSPGS(0.999)PGAGGVQSTAK 169.72 1.5675e-05 15115900.0 52448.0 66208.0 161978.0 55665.0 118266.0 78371.0 70686.0 77993.0 75652.0 50650.0 True False 61326.410504781335 72780.69268657148 165840.16982498553 52546.27051836494 95092.62627958467 74261.08679573944 63990.11035767739 75945.76639041428 76758.26738047702 59832.4440548206 1.0249691697132064 1.2164084860027988 2.7717431979385116 0.8782237020139139 1.5893154254647772 1.2411508165653204 1.0694884918798804 1.269307439970697 1.2828870455324937 1.0 15.86864037541466 -6.612340706305414 1.4724737145584936 1.1741729139389048 1.5558889506391393 0.09171036512781339 0.49026510694987124 1.0215968872402323 4.5847649278074 0.2112324386984663 0.21692560065435182 2.44151442027935e-07 6.612340706305414 0.3817160367002346 TGSPGS(ph)PGAGGVQSTAK ddPTM_PC-9_Lapatinib_30min_R1 4 TGSPGSPGAGGVQSTAK 17 0 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 TGSPGS(1)PGAGGVQSTAK;T(0.199)GS(0.08)PGS(0.721)PGAGGVQSTAK;T(0.023)GS(0.264)PGS(0.713)PGAGGVQSTAK;T(0.001)GS(0.008)PGS(0.987)PGAGGVQS(0.002)T(0.001)AK 216.16 2.3311e-22 25808700.0 63388.0 79084.0 79912.0 75656.0 100348.0 86950.0 103797.0 100884.0 87309.0 93596.0 True False 62484.07549606444 78900.88585690645 73341.94382924068 81219.99462101753 94445.72793175881 83231.35119034977 109171.1007773785 105571.43893514884 77475.34101547104 109773.94389116912 0.5692068015522127 0.7187578678518601 0.6681179634208327 0.7398840903588174 0.8603656257936142 0.7582068042746654 0.9945083223539067 0.9617167352556205 0.7057716819601635 1.0 16.74417612914447 -3.6721145238934882 0.2502079079989975 0.9641468139656432 5.371529295220632e-15 0.5930312108148941 0.09000915770516787 12.433426613513621 0.4232413830925574 0.12376698796098246 4.056860946307025 0.00021275779275539984 3.6721145238934882 -0.9641468139656378 TGSPT(ph)FVR ddPTM_PC-9_AZD4547_30min_R2 1 TGSPTFVR 8 0 Q9UPP1-4;Q9UPP1-3;Q9UPP1-2;Q9UPP1;Q9UPP1-5;B0QZZ4;Q5JPR8;B0QZZ2;B0QZZ3;B0QZE1 Q9UPP1-4 PHF8 Histone lysine demethylase PHF8 1 T(0.003)GS(0.221)PT(0.776)FVR 114.89 0.008943000000000001 11543000.0 80477.0 63770.0 132290.0 149860.0 129360.0 113550.0 84487.0 142080.0 98283.0 124110.0 True False 106067.0119744118 84382.40540968237 130535.74816324962 115312.0923139196 111400.59691613697 106449.70054967774 92006.17932699366 120124.80067359848 103478.03873127869 119764.94667614394 0.8856265119144361 0.704566801485418 1.0899328374956905 0.9628200530638961 0.9301602848567622 0.8888218423169183 0.7682229390189378 1.00300466879034 0.8640093917554472 1.0 16.86984619010542 TGSQEGT(ph)SMEGSRPAAPAEPGTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGSQEGTSMEGSRPAAPAEPGTLK 24 1 Q8IV36-3;Q8IV36-2;Q8IV36 Q8IV36-3 HID1 Protein HID1 1 T(0.06)GS(0.209)QEGT(0.354)S(0.354)MEGS(0.023)RPAAPAEPGTLK 44.341 0.037217 8569300.0 42302.0 39857.0 33703.0 45695.0 39444.0 31035.0 38680.0 32596.0 29015.0 36237.0 True False 49462.89309741574 43813.7395542635 34506.60733933929 43134.85729518886 31715.231351123195 29407.469966004952 35015.95038105081 31740.389538316806 29439.28948401294 42806.48124806581 1.1555000938006486 1.0235305093254587 0.8061070738183708 1.0076711758955401 0.7408978833679826 0.6869863887103245 0.8180058103381947 0.7414856024810724 0.6877297228289032 1.0 15.385541628431469 -4.463103832969846 0.6833185945706975 0.7707730265248189 1.5771108366660787 0.5410304319707353 0.10658476592380788 3.2818188611431593 0.8558597584532085 0.04442621744515817 2.263998432525961 3.4426761195986755e-05 4.463103832969846 0.8063378101412597 TGSQGQCTQVR ddPTM_PC-9_AZD4547_30min_R2 1 TGSQGQCTQVR 11 0 P62857 P62857 RPS28 40S ribosomal protein S28 0 123.62 0.0025472 1519200.0 907.41 2333.3 2045.8 2549.4 2186.7 2668.6 1823.0 1113.1 1037.7 2655.0 False True 1195.9475046994937 3087.4935948316074 2018.6713552980257 1961.6752178373606 1883.1144501895205 2501.7320201397647 1985.2434683810493 941.0959714934 1092.5507034934626 2562.049258119106 0.4667933299524001 1.205087523218913 0.7879127807167947 0.7656664725008051 0.7350032183112606 0.976457424544748 0.7748654566612388 0.3673215760825352 0.4264362599708735 1.0 11.323082497953282 -7.597684136190938 7.861179792055393 0.5493846508391842 0.8355918443211449 0.14309934899264343 0.23686665849312485 0.3588712037177257 32.74413297258319 0.10620357254404593 0.061025796216660044 2.5253167759540093e-08 7.597684136190938 0.28620719348196066 TGSQGQCTQVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TGSQGQCTQVR 11 0 P62857 P62857 RPS28 40S ribosomal protein S28 0 ;; 123.67 0.0025347 4177500.0 3426.5 4167.5599999999995 5765.0 6138.1 11027.6 5982.1 6561.2 4405.74 4006.19 1663.1399999999999 False True 4006.538773540139 4581.287814355482 5902.459463884253 5794.202156988702 8866.820942288969 5668.3881451148145 5939.675637025611 4290.093993267391 4064.772949783135 1964.6541165910032 2.0393099934008436 2.3318546382631293 3.0043249923940745 2.94922251609489 4.513171487749893 2.885183756899864 3.023267855072587 2.1836383091754628 2.068950923960184 1.0 10.94005962859537 -8.377283150101876 1.2292132007750534 1.0546253668576024 2.9985603270315493 0.4883729266291863 0.6238871543600525 0.4032132560853264 1.2876796754982298 0.6390762262384959 0.20188802363304853 4.1948539989740134e-09 8.377283150101876 1.9439349601739468 TGSQGQCTQVR ddPTM_PC-9_Lapatinib_30min_R1 3 TGSQGQCTQVR 11 0 P62857 P62857 RPS28 40S ribosomal protein S28 0 ;; 129.0 0.0012970999999999998 23292100.0 5995.200000000001 7659.98 7417.200000000001 8779.2 7000.799999999999 6551.47 8430.099999999999 5601.1 5888.299999999999 7609.5 False True 5909.707348614972 7642.243786937768 6807.386447219978 9424.851654552669 6589.0267081023685 6271.278900322495 8866.569329203903 5861.347553820844 5225.097647452128 8924.791935978601 0.6621675206557042 0.8562937760072048 0.7627501566481674 1.0560304063289332 0.738283509057501 0.7026806837973474 0.99347630654111 0.6567489299321294 0.5854587630651803 1.0 13.123602820590289 TGSQLGEQELPDFQPQT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGSQLGEQELPDFQPQTPR 19 0 Q15697;V9GZ69;I3L2H2;Q15697-2 Q15697 ZNF174 Zinc finger protein 174 1 TGSQLGEQELPDFQPQT(1)PR 177.12 7.103899999999999e-37 0.0 3212.2 2957.1 4798.3 4938.1 5160.8 4463.0 3945.1 4982.5 5195.2 2687.5 True False 3755.9620161580747 3250.6613452069296 4912.709669654085 4661.4342665362055 4149.5782871127785 4228.952423337524 3571.391567949421 4851.7146543951285 5271.169971647213 3174.7224757617055 1.1830835749688366 1.0239198449707023 1.5474453931521643 1.4682966155704038 1.3070680410000808 1.3320699543423489 1.1249460685827486 1.528232685356557 1.6603561451091913 1.0 11.632414766202983 -5.2501622522037925 24.97769136900994 1.3809235046485764 1.1035016927992423 0.23696898984465975 0.19138475483607495 1010.9029335963755 2239036.947850294 0.04851029662314716 0.12585854518051862 5.621312739891463e-06 5.2501622522037925 -0.2774218118493341 TGSS(ph)GALGPPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TGSSGALGPPER 12 0 Q9BZL4-3;K7EL81;Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-3;Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 T(0.019)GS(0.241)S(0.74)GALGPPER;T(0.005)GS(0.06)S(0.936)GALGPPER 96.06700000000001 0.0043994 12496600.0 30032.0 39054.0 33671.0 44832.0 41491.0 32333.0 46779.0 33819.0 30362.0 27458.0 True False 35115.824440962344 42931.0230211056 34473.84433797859 42320.20838730506 33361.13639563564 30637.400561006536 42347.75446936855 32931.28708419242 30805.98681073928 32435.918042591595 1.082621567697013 1.3235642957517924 1.0628293083214415 1.3047328684125543 1.02852450027248 0.9445516701816972 1.3055821146718192 1.0152722374298258 0.949749187622436 1.0 14.985304651932875 -6.2873251418201255 24.714111165204937 1.04982224334665 1.1934027089227555 0.27115375297270217 0.12218735760710896 947.3510743009259 904468.7171466982 0.03736061326204193 0.04237651405612619 5.160298902189158e-07 6.2873251418201255 0.1435804655761055 TGSS(ph)PTQGIVNK ddPTM_PC-9_AZD4547_30min_R2 1 TGSSPTQGIVNK 12 0 E9PFH7;A0A087WYG2;A0A669KB35;Q9UPT6 E9PFH7 MAPK8IP3 C-Jun-amino-terminal kinase-interacting protein 3 1 T(0.151)GS(0.128)S(0.676)PT(0.045)QGIVNK 75.73899999999999 0.019417 17268000.0 50786.0 54053.0 60937.0 71103.0 73653.0 59728.0 56307.0 59880.0 62338.0 61991.0 True False 66934.89158557708 71524.57518597387 60128.9355644715 54711.30188039932 63427.55229332278 55993.19871801995 61318.21391888738 50626.921905511466 65633.05941445065 59820.71395859192 1.1189249869520048 1.1956489726198085 1.0051524227225528 0.9145879121113574 1.0602941371984882 0.9360168913526945 1.0250331341971617 0.8463108939247294 1.0971627563636577 1.0 15.868357508635489 -5.3385175902401665 5.374030197344916 0.9784554479051459 1.1566767228367811 0.48523104918405746 0.07073395247140533 0.14931257811663595 7.5747706882799015 0.017180341692893075 0.037127907457278425 4.58651068666385e-06 5.3385175902401665 0.1782212749316352 TGSS(ph)PTQGIVNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TGSSPTQGIVNK 12 0 E9PFH7;A0A087WYG2;A0A669KB35;Q9UPT6 E9PFH7 MAPK8IP3 C-Jun-amino-terminal kinase-interacting protein 3 1 T(0.109)GS(0.109)S(0.78)PT(0.002)QGIVNK;TGS(0.001)S(0.999)PT(0.001)QGIVNK 176.99 0.00094766 29335000.0 88222.0 85090.0 89302.0 113100.0 121053.0 96180.0 100757.0 95166.0 89708.0 89505.0 True False 103156.24213607408 93537.17285978077 91431.29835972087 106763.37367514717 97333.53363623148 91136.15148478674 91212.5675424907 92667.9933367116 91019.80978913778 105731.54797880979 0.9756429760845662 0.8846666359082064 0.8647494537585423 1.0097589197932124 0.9205722936709354 0.8619579796850398 0.862680716268063 0.8764460098066821 0.8608576298095961 1.0 16.690046384002216 -6.63408406787354 6.767699182808217 0.8830463952253838 0.930040271858473 0.1016644576492467 0.05462844422679928 0.4405667874026849 24.631598006546756 0.01780958776605065 0.017779207302203233 2.3222872197372917e-07 6.63408406787354 0.04699387663308929 TGSS(ph)PTQGIVNK ddPTM_PC-9_Lapatinib_30min_R1 2 TGSSPTQGIVNK 12 0 E9PFH7;A0A087WYG2;A0A669KB35;Q9UPT6 E9PFH7 MAPK8IP3 C-Jun-amino-terminal kinase-interacting protein 3 1 T(0.007)GS(0.081)S(0.912)PTQGIVNK;T(0.012)GS(0.129)S(0.858)PTQGIVNK 195.71 1.3749000000000002e-05 32501000.0 189880.0 160801.0 158180.0 147263.0 179471.0 155876.0 156595.0 157640.0 172695.0 130292.0 True False 187172.27638027223 160428.67516408407 145175.05099245772 158093.21227496714 168914.86863356206 149209.54684470355 164702.72287478056 164964.52989311315 153244.2705410298 152812.79859682271 1.224846859025877 1.0498379496821786 0.9500189272462954 1.0345547868151812 1.1053712135671478 0.9764204845064981 1.07780712340285 1.0795203766168255 1.0028235327679946 1.0 17.221405853536346 -4.768277652155745 5.014804133058826 1.0320013985634497 1.2359910352784356 0.6144328175336213 0.04632412183202887 0.11218223426140865 7.456905000065312 0.011621119315103037 0.07996699140892434 1.7049920088956287e-05 4.768277652155745 0.20398963671498582 TGSS(ph)SPPGGPPKPGSQLDSMLGSLQSDLNK ddPTM_PC-9_AZD4547_30min_R2 4 TGSSSPPGGPPKPGSQLDSMLGSLQSDLNK 30 1 A0A1B0GTU4;F5GZ78;P49023;P49023-2;P49023-4;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 T(0.037)GS(0.122)S(0.374)S(0.374)PPGGPPKPGS(0.075)QLDS(0.011)MLGS(0.007)LQSDLNK;T(0.196)GS(0.077)S(0.237)S(0.214)PPGGPPKPGS(0.12)QLDS(0.095)MLGS(0.055)LQS(0.006)DLNK;T(0.039)GS(0.128)S(0.4)S(0.4)PPGGPPKPGS(0.026)QLDS(0.003)MLGS(0.003)LQS(0.001)DLNK;T(0.017)GS(0.108)S(0.433)S(0.433)PPGGPPKPGS(0.003)QLDS(0.004)MLGS(0.002)LQSDLNK 68.046 0.00017292 467280000.0 162998.0 169728.0 182068.0 227189.0 227305.0 210569.0 195710.0 210913.0 197383.0 200397.0 True False 214827.97343098247 224589.25678805952 179653.65935888194 174814.08608506032 195747.62431990146 197402.08714262536 213127.81085949283 178321.24214858306 207816.26241461877 193381.1620260995 1.1109043465256891 1.1613812557282495 0.9290132372595586 0.9039871529030666 1.0122372948275207 1.0207927446210254 1.1021125771843705 0.9221231286453646 1.0746458457342967 1.0 17.56108773783889 -5.251156146604331 24.978892801752064 0.9948567438892935 1.1361428165568135 0.453782793674673 0.0616669458063277 628.7202872959255 1527210.2797965219 0.01616153263888019 0.04171832628717554 5.608462926288323e-06 5.251156146604331 0.14128607266752002 TGSS(ph)SPPGGPPKPGSQLDSMLGSLQSDLNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TGSSSPPGGPPKPGSQLDSMLGSLQSDLNK 30 1 A0A1B0GTU4;F5GZ78;P49023;P49023-2;P49023-4;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 T(0.125)GS(0.125)S(0.344)S(0.344)PPGGPPKPGS(0.057)QLDS(0.003)MLGS(0.001)LQSDLNK;T(0.119)GS(0.119)S(0.379)S(0.379)PPGGPPKPGS(0.003)QLDSMLGSLQSDLNK;T(0.102)GS(0.102)S(0.397)S(0.397)PPGGPPKPGS(0.001)QLDSMLGSLQSDLNK 83.36 2.6263e-07 508404800.0 155323.0 168061.0 145042.0 196587.0 209119.0 193328.0 204091.0 208435.0 192451.0 150680.2 True False 181616.11613091378 184744.9854035442 148500.35135484845 185572.8677336534 168143.6331233022 183189.5393455069 184758.0229891172 202963.80210513787 195265.23179347845 177997.32747619296 1.020330578588068 1.03790875977199 0.8342841629164925 1.042559853930805 0.9446413353919109 1.0291701675689957 1.0379820057344875 1.1402631993577779 1.0970121549695462 1.0 17.441496054584732 -7.201377271006227 2.0267618692866174 1.08655738745163 0.9756949935458773 0.29825055348750407 0.06605424734067752 0.3787359547778942 3.0446525942306066 0.03182351145404674 0.021298068486700215 6.289595691762754e-08 7.201377271006227 -0.11086239390575281 TGSS(ph)SPPGGPPKPGSQLDSMLGSLQSDLNK ddPTM_PC-9_Lapatinib_30min_R1 1 TGSSSPPGGPPKPGSQLDSMLGSLQSDLNK 30 1 A0A1B0GTU4;F5GZ78;P49023;P49023-2;P49023-4;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 T(0.114)GS(0.114)S(0.383)S(0.383)PPGGPPKPGS(0.006)QLDSMLGSLQSDLNK 67.181 0.00019738 130280000.0 43945.0 32223.0 35724.0 34366.0 41913.0 34917.0 31471.0 33667.0 39118.0 28533.0 True False 43318.336241474 32148.389623275227 32786.91061862786 36893.39028161533 39447.75974412848 33423.681305502505 33100.41439121436 35231.29172742612 34712.11890919828 33464.891032167354 1.2944412757787034 0.9606602212561616 0.9797405462074327 1.1024506324001595 1.1787804629696905 0.9987685683295595 0.9891086858581836 1.0527836978031948 1.0372697426634994 1.0 15.030360696180233 TGSSS(ph)PPGGPPKPGSQLDSMLGSLQSDLNK ddPTM_PC-9_AZD4547_30min_R2 2 TGSSSPPGGPPKPGSQLDSMLGSLQSDLNK 30 1 A0A1B0GTU4;F5GZ78;P49023;P49023-2;P49023-4;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 T(0.061)GS(0.092)S(0.264)S(0.576)PPGGPPKPGS(0.005)QLDS(0.001)MLGSLQSDLNK;T(0.045)GS(0.052)S(0.158)S(0.577)PPGGPPKPGS(0.162)QLDS(0.006)MLGSLQSDLNK 90.921 1.9825e-09 796250000.0 81777.0 64662.0 83211.0 111154.0 106483.0 101747.0 83545.0 103413.0 91093.0 88163.0 True False 107780.38493273217 85562.72696567148 82107.5677708984 85529.16261218091 91699.67348037283 95384.7440055313 90980.34315188946 87432.8970443329 95907.99000995471 85076.44020472867 1.26686524110986 1.0057158804455453 0.9651034713407619 1.0053213604890239 1.0778503809010573 1.1211651989198965 1.0693952748017381 1.0276981128257556 1.1273155033186733 1.0 16.376472048409532 -8.598356765231337 0.005434639000877041 8.54964738195681e-05 2.102334221446957 0.05064366591639702 0.08187819529961624 29946.982507891167 99.54252704895882 19406.940073191665 19090.590316805246 2.5214086289142396e-09 8.598356765231337 2.1022487249731374 TGSSS(ph)PPGGPPKPGSQLDSMLGSLQSDLNK ddPTM_PC-9_Lapatinib_30min_R1 4 TGSSSPPGGPPKPGSQLDSMLGSLQSDLNK 30 1 A0A1B0GTU4;F5GZ78;P49023;P49023-2;P49023-4;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 T(0.051)GS(0.051)S(0.169)S(0.702)PPGGPPKPGS(0.018)QLDS(0.005)MLGS(0.002)LQSDLNK;T(0.089)GS(0.089)S(0.284)S(0.369)PPGGPPKPGS(0.141)QLDS(0.019)MLGS(0.009)LQS(0.001)DLNK;T(0.101)GS(0.101)S(0.334)S(0.433)PPGGPPKPGS(0.027)QLDS(0.002)MLGS(0.001)LQSDLNK;T(0.038)GS(0.038)S(0.143)S(0.777)PPGGPPKPGS(0.005)QLDSMLGSLQSDLNK 110.44 1.0777000000000001e-15 694345000.0 98238.0 87455.2 85627.4 86044.8 102048.4 97788.0 73139.3 75142.8 94699.1 73749.3 True False 96837.10810535707 87252.70285763148 78587.44570332258 92372.82162903817 96046.1137468737 93605.8351949618 76926.09508065664 78634.20881027797 84033.09013226799 86496.76824023484 1.119545967733767 1.0087394550429574 0.9085593288879299 1.0679337911502458 1.1104011826212588 1.0821888158293074 0.8893522457047556 0.9090999630400118 0.9715171080019513 1.0 16.40035861020764 -7.258819675233534 24.989441809197004 0.9349173252399247 1.044897245499765 0.40435789794527277 0.06324394920829664 256.46630066373893 2446452.2699693427 0.026889627005711132 0.019854209915119325 5.510364464738149e-08 7.258819675233534 0.10997992025984027 TGSSSPPGGPPKPGS(ph)QLDSMLGSLQSDLNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGSSSPPGGPPKPGSQLDSMLGSLQSDLNK 30 1 A0A1B0GTU4;F5GZ78;P49023;P49023-2;P49023-4;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 T(0.007)GS(0.007)S(0.017)S(0.042)PPGGPPKPGS(0.905)QLDS(0.02)MLGS(0.002)LQSDLNK 58.383 0.00066813 146330000.0 199120.0 202170.0 188470.0 242570.0 254100.0 237190.0 264420.0 243150.0 215030.0 188130.0 True False 232827.08320073344 222240.10150501714 192963.8395764554 228979.5893225507 204310.9290721127 224751.33885086878 239372.2233649808 236767.57013872074 218174.40695320646 222236.47976373957 1.0476546579942807 1.0000162967901642 0.8682815700716461 1.030342046301218 0.9193401969348884 1.011316139860579 1.0771058991730715 1.0653857116096745 0.9817218450595891 1.0 17.761736126692647 -6.992602102721793 24.649703914018648 1.03760344132142 0.9713100181844576 0.19633852339553493 0.055065532380425476 219.17421885683518 730279.9340653915 0.019288727965427403 0.01697580638367278 1.0171801987941408e-07 6.992602102721793 -0.06629342313696229 TGSSSPPGGPPKPGSQLDS(ph)MLGSLQSDLNK ddPTM_PC-9_Lapatinib_30min_R1 1 TGSSSPPGGPPKPGSQLDSMLGSLQSDLNK 30 1 A0A1B0GTU4;F5GZ78;P49023;P49023-2;P49023-4;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 T(0.003)GS(0.007)S(0.02)S(0.058)PPGGPPKPGS(0.006)QLDS(0.658)MLGS(0.238)LQS(0.011)DLNK 62.717 0.00073481 48544000.0 26069.0 20667.0 22253.0 18515.0 24798.0 20813.0 19426.0 17793.0 20361.0 18209.0 True False 25697.251279530912 20619.14683127669 20423.444239064094 19876.654864229386 23339.430394743824 19922.876507472683 20431.783227852004 18619.727736540004 18067.72976916475 21356.40138803262 1.2032575532098189 0.9654785212470738 0.9563148710301296 0.9307118040667454 1.092854080173939 0.9328761033044063 0.9567053389107614 0.8718569855581497 0.8460100295403361 1.0 14.38238094899895 -7.1484723815479345 1.9728027205657135 0.9010649568149905 1.0158405120483889 0.26303681367622456 0.08515687288528 0.4859968331560177 3.7163009420132855 0.04101833478521585 0.0284365319514698 7.104403481934166e-08 7.1484723815479345 0.11477555523339833 TGST(ph)SSKEDDYESDAATIVQK ddPTM_PC-9_AZD4547_30min_R2 2 TGSTSSKEDDYESDAATIVQK 21 1 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 T(0.054)GS(0.157)T(0.209)S(0.209)S(0.209)KEDDY(0.132)ES(0.008)DAAT(0.022)IVQK;T(0.01)GS(0.028)T(0.298)S(0.298)S(0.298)KEDDY(0.057)ES(0.011)DAATIVQK 58.082 0.009670999999999999 114576000.0 88081.0 86602.0 75374.0 90293.0 80014.0 75822.0 86294.0 74875.0 84308.0 74620.0 True False 116088.92580138631 114594.4029055873 74374.49151150325 69477.34386294374 68905.43724217522 71080.83835383235 93973.99882637082 63304.78920633223 88764.34876180667 72007.5765125603 1.6121765434104962 1.591421465012068 1.032870360503385 0.9648615774594884 0.9569192657130464 0.9871299909869026 1.305057097845515 0.8791406720276158 1.232708460148266 1.0 16.135861091965907 -5.258208754093672 9.708918742384666 1.0416564122872956 1.6024186977257073 0.7674606067505558 0.12262350791723198 0.051305247106352654 92.41903702853644 0.030679008024250793 0.07278107886453815 5.518121337421246e-06 5.258208754093672 0.5607622854384118 TGSVQTPPDLES(ph)SEEVDAAEGAPEVVGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGSVQTPPDLESSEEVDAAEGAPEVVGPK 29 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7;H7BZ26 E9PHV5 SSFA2 Sperm-specific antigen 2 1 TGSVQT(0.003)PPDLES(0.62)S(0.376)EEVDAAEGAPEVVGPK 74.05 0.00064918 0.0 15778.0 14689.0 14583.0 15782.0 17341.0 14993.0 16384.0 13904.0 14481.0 13360.0 True False 18448.90377029515 16147.226843780938 14930.714026335474 14897.785705934348 13943.155533410087 14206.740686331954 14831.988910112117 13539.034732505741 14692.757229639532 15782.0622422982 1.1689792808476849 1.0231379521811823 0.9460559587909246 0.9439695191421902 0.8834812155309096 0.9001827814527206 0.9398004318067034 0.8578748787480497 0.9309782843373172 1.0 13.945998114200213 -4.496693067475665 1.0885730695532339 0.9129502986187082 1.4429958900924742 0.8116033169725368 0.036527082819831684 1.0768832220730862 0.6998511032158644 0.010738292304012768 0.7623895731573145 3.1864487113336956e-05 4.496693067475665 0.530045591473766 TGSVQTPPDLESS(ph)EEVDAAEGAPEVVGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGSVQTPPDLESSEEVDAAEGAPEVVGPK 29 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7;H7BZ26 E9PHV5 SSFA2 Sperm-specific antigen 2 1 TGSVQT(0.002)PPDLES(0.425)S(0.572)EEVDAAEGAPEVVGPK 73.212 1.4455999999999998e-05 3380700.0 46902.0 49702.0 51388.0 58007.0 60386.0 49351.0 49247.0 47522.0 39635.0 37547.0 True False 54841.58224327435 54636.08609092518 52613.28481007527 54757.055851231424 48553.79678452804 46762.94668252975 44581.967642595926 46274.59785372106 40214.58689294685 44353.97387811155 1.2364525080432167 1.23181941354499 1.1862135499890267 1.2345467849556935 1.0946887626790318 1.0543124458484432 1.0051403232799596 1.0433021848479134 0.9066738192041126 1.0 15.436775747602502 -6.621115233988653 1.0294729806250709 0.980874312903701 1.2337619837347358 0.8936686491878039 0.03619838005765017 0.1502419825504862 0.3426590173902091 0.018288203376199165 0.019181213164759885 2.3926808076626536e-07 6.621115233988653 0.2528876708310348 TGT(ph)PSDPR ddPTM_PC-9_AZD4547_30min_R2 2 TGTPSDPR 8 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 T(0.194)GT(0.751)PS(0.055)DPR;T(0.122)GT(0.826)PS(0.052)DPR 102.62 0.010325 68411000.0 714790.0 812770.0 616180.0 842570.0 1001920.0 955370.0 1074690.0 933660.0 1074110.0 1096360.0 True False 942078.3514443852 1075482.0079163788 608009.0505951403 648328.5040767342 862820.7023980839 895630.5628722657 1170335.3280496034 789384.3003724096 1130885.2617609743 1057976.7701060108 0.8904527755840873 1.0165459566835422 0.5746903597271015 0.612800320759189 0.8155384189689042 0.8465503101571145 1.1062013468710983 0.7461263070013457 1.0689131309070783 1.0 20.012876520007886 -7.002933111656159 4.4417121594421 0.9621130862528507 0.7770357972747549 0.2801466576398749 0.14849486060504982 0.3082248410106474 15.30625683837146 0.059089286066945995 0.048672744903484146 9.932690160643975e-08 7.002933111656159 -0.18507728897809583 TGT(ph)PSDPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TGTPSDPR 8 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 T(0.014)GT(0.675)PS(0.311)DPR;T(0.326)GT(0.668)PS(0.006)DPR 111.06 0.009173899999999999 70844000.0 611870.0 900760.0 772110.0 1023420.0 1402020.0 1038190.0 1011410.0 959020.0 918970.0 976030.0 True False 715447.506016637 990181.4998845492 790520.0306434828 966081.0953724057 1127304.2454847838 983745.488770959 915601.9228257142 933846.7411656812 932408.1977295646 1152976.5127507735 0.6205221859287671 0.858804571415052 0.6856341147465864 0.8379017999833559 0.9777339200043713 0.8532224879619943 0.7941201860576236 0.8099442884033327 0.808696610397573 1.0 20.136931693516708 -3.8430653330653923 0.7655575023204981 0.8557880348126563 1.0009961812071767e-12 0.38080291202007843 0.0857448337916465 11.69485847642667 1.801561797784633 0.032490405526212414 11.986404511325292 0.00014352735018255896 3.8430653330653923 -0.8557880348116553 TGT(ph)PSDPR ddPTM_PC-9_Lapatinib_30min_R1 1 TGTPSDPR 8 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 T(0.159)GT(0.555)PS(0.286)DPR 101.46 0.011196 38082000.0 567610.0 657880.0 344540.0 453840.0 441670.0 348820.0 388230.0 408220.0 339050.0 321120.0 True False 559515.7773130753 656356.7192800263 316213.2511628612 487216.90756585944 415691.8389566297 333901.7817391353 408330.6497760208 427187.3914803776 300862.6186452193 376625.1641344959 1.4856038061048615 1.7427319833722952 0.839596716511324 1.2936387526986124 1.1037282649764284 0.8865625920308826 1.0841831312955037 1.1342507940542856 0.7988383339616119 1.0 18.522769870987972 -5.2575450339816445 24.999525812431724 1.033027114239567 1.6141679329153729 0.7083746953194145 0.15285292175618798 167.97153014952184 1078272.3336441624 0.03805056654043624 0.09316847829334017 5.526560975340454e-06 5.2575450339816445 0.5811408186758058 TGTAYTFFTPNNIK ddPTM_PC-9_Lapatinib_30min_R1 1 TGTAYTFFTPNNIK 14 0 P17844-2;P17844;J3KTA4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 142.12 0.00066768 4445200.0 45543.0 41660.0 43216.0 35892.0 31966.0 28112.0 33610.0 33031.0 32209.0 37469.0 False True 44893.54846843666 41563.538829582794 39662.947298584186 38531.61741220207 30085.822727574025 26909.715292272707 35350.16134500697 34565.74084559395 28581.28324419366 43945.46672569579 1.0215740510542013 0.9457980976517827 0.9025492332612426 0.8768052835281839 0.6846172078537112 0.6123433723037025 0.8044097373151126 0.7865598757057386 0.6503806962068652 1.0 15.423426728770787 -5.914719430106895 2.1557810820983043 0.7422891178467115 0.9666507537722853 0.4243329684353224 0.10451646630667652 0.27786256633148754 2.621347235592451 0.03171833850235307 0.0531396683591193 1.2169719545003617e-06 5.914719430106895 0.2243616359255738 TGTGDIATCYS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 TGTGDIATCYSPR 13 0 Q9NZN5-2;Q9NZN5;E9PMR6 Q9NZN5-2 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 TGTGDIATCYS(1)PR;TGTGDIATCYS(1)PR 155.39 0.0001182 20123700.0 95224.0 102407.0 102656.0 139448.0 143251.0 117044.0 108519.0 139942.0 114375.0 120116.0 True False 125503.2512177569 135508.06007196708 101294.71436576125 107300.41805012319 123363.0713422505 109725.22017733607 118176.98077084086 118317.17944724586 120420.62899880979 115910.77540046471 1.0827574121918413 1.1690721557490658 0.8739024824550965 0.9257156436009227 1.064293383561956 0.9466352010694612 1.0195512916081058 1.0207608312382275 1.0389079754040451 1.0 16.822655164113456 -5.242007642643739 24.99985214578212 0.987366308009203 1.1259147963667062 0.4865058695045842 0.0573968590445578 714.2300838610673 918887.8612409504 0.014973427462541794 0.039493706753530367 5.727859511030219e-06 5.242007642643739 0.13854848835750322 TGTGDIATCYS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGTGDIATCYSPR 13 0 Q9NZN5-2;Q9NZN5;E9PMR6 Q9NZN5-2 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 TGTGDIATCYS(1)PR 132.06 6.0743000000000004e-05 6134500.0 10456.0 18382.0 15514.0 16799.0 19241.0 19819.0 22680.0 23369.0 20735.0 17667.0 True False 12225.994284586515 20206.8434775942 15883.912597172633 15857.806493092841 15470.864172674204 18779.656750644503 20531.586211019465 22755.588511502203 21038.210148233942 20869.887248104948 0.5858198532288034 0.9682296428999178 0.7610924011395865 0.7598415029545874 0.7413008028626992 0.8998446674574035 0.983789992103757 1.090355124633866 1.0080653478443817 1.0 14.349135185747281 -7.0940688093140745 2.241050252585715 1.0340808862435238 0.7744376867835556 0.6397829503802317 0.09069622038441033 0.1999338468605599 1.9779240378329674 0.039058576174428546 0.028801602311627567 8.052508477101043e-08 7.0940688093140745 -0.25964319945996817 TGTGDIATCYS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 TGTGDIATCYSPR 13 0 Q9NZN5-2;Q9NZN5;E9PMR6 Q9NZN5-2 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 TGTGDIATCYS(1)PR;TGTGDIATCYS(1)PR 153.0 3.9384000000000004e-08 0.0 54104.0 59380.0 62545.0 73651.0 71306.0 69156.0 57900.0 59781.0 68809.0 92881.0 True False 53332.467038541574 59242.509258296326 57402.79153068185 79067.5402325337 67111.92127298993 66198.3590905098 60897.778693124186 62558.64350127005 61059.005829107504 108935.35709384715 0.48957903532271874 0.5438317809640011 0.5269436210800658 0.7258207283831409 0.6160710632744648 0.6076847853308115 0.5590267505219735 0.5742730842418422 0.5605067762939955 1.0 16.73311275929965 -11.562634931437938 2.272566201607913 1.5154706936025146 0.5813195412509476 0.8141158860637854 0.0604496304051739 8731006.651264273 2959649.2549566044 23411571.72397823 0.016995034483408448 2.73756896376254e-12 11.562634931437938 -0.934151152351567 TGTITTFEHAHNMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TGTITTFEHAHNMR 14 0 P13639 P13639 EEF2 Elongation factor 2 0 ; 84.169 0.004121199999999999 10362100.0 44082.0 43032.0 51238.0 57196.0 61626.0 58035.0 53667.0 68802.0 54615.0 39945.0 False True 51544.211940813235 47303.932571419515 52459.70824119707 53991.4935519339 49550.82768594254 54991.5424352214 48583.273244567084 66996.02040174493 55413.64105357111 47186.712295554 1.0923459048802984 1.0024841797650852 1.1117474748529979 1.1442096922065292 1.0501012949489021 1.1654031349075953 1.0295964876778387 1.419806914754207 1.1743484205148207 1.0 15.526093035657931 TGTITTFEHAHNMR ddPTM_PC-9_Lapatinib_30min_R1 1 TGTITTFEHAHNMR 14 0 P13639 P13639 EEF2 Elongation factor 2 0 80.312 0.0065482 5582000.0 31336.0 33860.0 40112.0 34352.0 37378.0 36206.0 33052.0 32847.0 37349.0 30811.0 False True 30889.142893681405 33781.59925035219 36814.14619679769 36878.36067491267 35179.49952797543 34657.55378030824 34763.27083532194 34373.19153386893 33142.36231759411 36136.64029692314 0.8547873471323083 0.9348295517452554 1.018748447401521 1.0205254382226752 0.9735132884218567 0.959069617306376 0.9619950983180322 0.95120053362558 0.9171401116781744 1.0 15.141174761449797 -4.856215611672089 3.4359823276035195 0.9742132578422161 0.8488584798775737 0.5956157463352414 0.030172747593648578 0.19836827840036145 3.905748194456964 0.008398597417259136 0.05796717940051975 1.3924653220989204e-05 4.856215611672089 -0.12535477796464245 TGTLQDLIQHGS(ph)PINNECHPSLER ddPTM_PC-9_AZD4547_30min_R2 4 TGTLQDLIQHGSPINNECHPSLER 24 0 A0A2R8YH03;Q5VWN6 A0A2R8YH03 FAM208B Protein FAM208B 1 TGTLQDLIQHGS(1)PINNECHPSLER;TGTLQDLIQHGS(1)PINNECHPSLER;T(0.002)GT(0.002)LQDLIQHGS(0.996)PINNECHPSLER;TGTLQDLIQHGS(0.998)PINNECHPS(0.001)LER 102.66 2.0549e-06 20131400.0 34574.7 37940.8 91458.0 186621.0 120493.0 112936.0 74439.0 132793.0 77456.0 103608.0 True False 45568.73540156445 50204.421627217744 90245.2071624044 143598.41171570812 103764.62681057553 105874.09406674064 81063.92679254888 112272.89312956909 81550.166030442 99980.71545582083 0.45577524819474036 0.50214105188517 0.9026261389605846 1.4362610935621976 1.0378464120556001 1.0589451534133496 0.8107956261662197 1.1229454862140877 0.8156589564162214 1.0 16.609362230444376 -5.317004750138164 3.8666821050469102 1.0438482337381625 0.46828635195826673 0.639775733553795 0.1654825414463143 0.13199586459049853 4.028026409678963 0.04498771087289087 0.10798849141768536 4.819425263030127e-06 5.317004750138164 -0.5755618817798958 TGTLQDLIQHGS(ph)PINNECHPSLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TGTLQDLIQHGSPINNECHPSLER 24 0 A0A2R8YH03;Q5VWN6 A0A2R8YH03 FAM208B Protein FAM208B 1 T(0.061)GT(0.061)LQDLIQHGS(0.878)PINNECHPSLER 75.10600000000001 0.0002457 3961100.0 6724.7 10844.0 16628.0 21152.0 21445.0 16888.0 14490.0 16309.0 17537.0 9702.3 True False 7863.058891120787 11920.520654500675 17024.47458204116 19966.92201570926 17243.006194220576 16002.363550375114 13117.402301484653 15880.906030813872 17793.445448255537 11461.250186635452 0.6860559505357988 1.0400715855937568 1.4853942026230944 1.7421242613647823 1.5044611986855516 1.396214487057868 1.1445001276370688 1.3856172557276536 1.5524873079730717 1.0 13.48447680058019 -4.999436257311833 2.8945331808172083 1.420262549780649 0.688879074839326 0.5693390541060217 0.1979931926094139 0.20597814920363772 3.205762972528036 0.05353979674057242 0.27954829019195404 1.0012989083617438e-05 4.999436257311833 -0.7313834749413229 TGTLQDLIQHGS(ph)PINNECHPSLER ddPTM_PC-9_Lapatinib_30min_R1 1 TGTLQDLIQHGSPINNECHPSLER 24 0 A0A2R8YH03;Q5VWN6 A0A2R8YH03 FAM208B Protein FAM208B 1 TGTLQDLIQHGS(1)PINNECHPSLER 74.733 0.00025519 4100200.0 7236.6 5694.3 17108.0 9201.0 13349.0 19611.0 13819.0 13754.0 22223.0 6664.0 True False 7133.4047569700915 5681.115198206747 15701.446278789765 9877.672233636222 12563.838065143776 18772.28324547383 14534.480203113695 14393.061051445597 19720.011721435483 7815.863520778162 0.9126828709337387 0.7268698056335974 2.008920221936846 1.2637979421437981 1.6074792032567244 2.401818199047164 1.8596128456535044 1.8415189842020934 2.5230752390968214 1.0 12.932189560103541 -5.12556457985104 0.8239706278987969 1.934580725666519 0.3967283456686656 0.373839507186852 0.4677163388711814 1.5831606544007746 1.1636141902743584 0.17837184232181838 2.022827352745199 7.4891998537742716e-06 5.12556457985104 -1.5378523799978534 TGTPS(ph)DPR ddPTM_PC-9_Lapatinib_30min_R1 1 TGTPSDPR 8 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 T(0.038)GT(0.418)PS(0.544)DPR 97.473 0.005802399999999999 30183000.0 672730.0 759250.0 445870.0 599970.0 542610.0 407140.0 406370.0 514040.0 458680.0 416680.0 True False 663136.7468364278 757492.0032731807 409212.28970797284 644093.7952412497 510694.7466123047 389727.571289695 427409.85021631914 537924.1749952803 407018.62828547106 488702.5828087994 1.356933174007542 1.5500061385383404 0.837344233697397 1.3179668327909078 1.0450011204710772 0.7974739340433821 0.874580706653518 1.1007189114974218 0.8328554883957172 1.0 18.898597203731036 -5.162610840146512 0.7515249289272925 0.9348490030279183 1.6243775234702102 0.4825611284920809 0.17671307893372434 1.511391148982079 0.9298812330426496 0.07495628503260313 0.8025684977786353 6.876843798804601e-06 5.162610840146512 0.689528520442292 TGVAVNKPAEFTVDAK ddPTM_PC-9_AZD4547_30min_R2 1 TGVAVNKPAEFTVDAK 16 1 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 134.37 6.2927e-06 9785600.0 28785.0 19423.0 40550.0 48367.0 38807.0 33197.0 26820.0 40954.0 36235.0 41754.0 False True 37938.03123480557 25701.104912533454 40012.280505100694 37216.73541270091 33419.31790757982 31121.1863421194 29206.9280427755 34625.5003292972 38150.30812478138 40292.2051689285 0.9415724722870625 0.6378679152649844 0.9930526348048165 0.9236708503956678 0.8294238989270128 0.7723872697371905 0.7248778745249352 0.8593597740338819 0.9468409079332583 1.0 15.298213145056268 -8.328521814266855 2.9238342214932027 0.9939738116086317 0.8297753686023673 0.24348182128919382 0.09980894842242488 0.36838660411346164 5.844596729652475 0.09465993253057033 0.026144826898126805 4.693298596590816e-09 8.328521814266855 -0.1641984430062644 TGVAVNKPAEFTVDAK ddPTM_PC-9_Lapatinib_30min_R1 2 TGVAVNKPAEFTVDAK 16 1 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 94.007 0.0034469 26251000.0 89804.0 77204.0 91677.0 74857.0 89981.0 86806.0 92579.0 87117.0 83157.0 87934.0 False True 88523.37849196339 77025.23888139955 84139.67094345402 80362.2334956315 84688.49448945244 83093.50973466931 97372.2876274741 91164.77385624459 73790.9829779692 103133.2747353102 0.8583396456590479 0.7468514800784084 0.8158343770174763 0.7792076194795502 0.821155875315741 0.8056905974131762 0.9441403647598549 0.8839511214030334 0.715491514909737 1.0 16.65415035079574 -7.107440642434224 11.526209248662244 0.8762139801600773 0.8016422270691126 0.22570247976022284 0.07289090888545721 0.995972060903742 101.78241878130105 0.026953187802785643 0.020878611778565696 7.808351541504952e-08 7.107440642434224 -0.07457175309096475 TGVPS(ph)TASVGK ddPTM_PC-9_AZD4547_30min_R2 1 TGVPSTASVGK 11 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7;H7BZ26 E9PHV5 SSFA2 Sperm-specific antigen 2 1 T(0.01)GVPS(0.917)T(0.045)AS(0.029)VGK 89.46 0.0092704 3688600.0 38801.0 40818.0 36477.0 49582.0 54511.0 54951.0 41458.0 52301.0 37994.0 55582.0 True False 51138.910889063445 54011.62026050509 35993.29114635161 38151.63593426375 46943.08857835143 51514.90528318229 45147.68168521201 44219.0822074174 40002.28527371167 53636.091097844146 0.9534421663162349 1.007001426744091 0.6710647701878917 0.7113053012134439 0.8752145732006609 0.9604522669112419 0.8417407152742098 0.8244277556832389 0.7458091082875263 1.0 15.710916479594902 -10.831477596840783 5.294893154567474 1.0000342732658771 0.8430170900468392 0.1663498349806688 0.10517815298943953 4.570455327015322e-05 5.96817102088106e-06 0.10937773830989932 0.026522212474851776 1.4740845799316073e-11 10.831477596840783 -0.1570171832190379 TGVPSTAS(ph)VGK ddPTM_PC-9_AZD4547_30min_R2 1 TGVPSTASVGK 11 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7;H7BZ26 E9PHV5 SSFA2 Sperm-specific antigen 2 1 TGVPS(0.023)T(0.057)AS(0.92)VGK 97.631 0.0053106 35904000.0 185900.0 190340.0 180520.0 230430.0 208040.0 215450.0 188590.0 220850.0 182440.0 185080.0 True False 245012.33303979013 251863.68269843073 178126.18685032747 177307.9236080109 179157.23703179567 201977.87744102292 205374.14465276067 186722.70712812635 192083.40594135813 178600.4055339676 1.3718464541402835 1.4102077872971535 0.9973448062325372 0.9927632755250889 1.0031177504673816 1.1308926026072725 1.1499086132461276 1.045477509246831 1.075492552030215 1.0 17.446375830714423 -5.257572299811748 24.948795427449575 1.053826821011623 1.3910271594736472 0.8661629159148447 0.05369681687299569 113.08897562743168 729595.6074896563 0.015372686450929877 0.03758012614982297 5.526214018266854e-06 5.257572299811748 0.33720033846202413 TGVPSTAS(ph)VGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TGVPSTASVGK 11 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7;H7BZ26 E9PHV5 SSFA2 Sperm-specific antigen 2 1 TGVPS(0.033)T(0.194)AS(0.773)VGK;TGVPST(0.013)AS(0.987)VGK 126.83 0.00039084 56186000.0 357520.0 363830.0 305450.0 361450.0 332450.0 278250.0 300000.0 292450.0 241880.0 265200.0 True False 418041.07465812715 399948.6379312968 312733.08642557566 341199.12833671056 267308.80901229306 263658.0801688697 271581.8281880875 284773.4973763879 245417.03740799686 313278.66067795444 1.3344064793735404 1.2766545830660254 0.9982585017083573 1.0891234264036194 0.853262103565625 0.8416088079484804 0.8669017787562281 0.9090101980138717 0.78338255429495 1.0 18.257086976726107 -5.264722190103431 0.8769240192395288 0.8672364774318605 1.4529213782436852 0.8298337232999364 0.07328613080264793 0.45344390840979715 0.43942750616378073 0.027111119303967143 0.22213424088569533 5.435979495382816e-06 5.264722190103431 0.5856849008118247 TGVPSTAS(ph)VGK ddPTM_PC-9_Lapatinib_30min_R1 2 TGVPSTASVGK 11 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7;H7BZ26 E9PHV5 SSFA2 Sperm-specific antigen 2 1 TGVPS(0.131)T(0.131)AS(0.738)VGK;T(0.001)GVPS(0.078)T(0.185)AS(0.736)VGK 89.43 0.0092867 79313000.0 197538.0 194829.0 174178.0 174084.0 188133.0 170925.0 146212.0 154855.0 168252.0 122181.0 True False 194721.07189596735 194377.8854207584 159857.75718652323 186886.71808720016 177067.38682370924 163614.9361956358 153782.1419391895 162050.1286259713 149301.68798789376 143299.82305405117 1.358836792300299 1.356441908148352 1.1155474848439038 1.3041657282208121 1.2356427457479924 1.1417664914626027 1.0731495591671771 1.1308466763761997 1.0418832682827441 1.0 17.128677302604906 -2.198430046237829 0.1551688044440676 0.9449248508346908 2.298508360417114 0.7528899496172238 0.061363119088085796 27.02140643240877 0.33012129623689607 0.21193055549298623 7.976369318081635 0.006332423526855122 2.198430046237829 1.3535835095824231 TGYES(ph)GEYEMLGEGLGVK ddPTM_PC-9_AZD4547_30min_R2 3 TGYESGEYEMLGEGLGVK 18 0 F8VW18;F8W1I6;Q13561;Q13561-3;Q13561-2;H0YHL1;F8VX93;F8VRV7 F8VW18 DCTN2 Dynactin subunit 2 1 T(0.003)GYES(0.89)GEY(0.107)EMLGEGLGVK;T(0.041)GY(0.031)ES(0.902)GEY(0.027)EMLGEGLGVK;T(0.01)GYES(0.99)GEYEMLGEGLGVK 118.55 0.00062228 3811300.0 54318.0 45532.0 66493.0 82956.0 73023.0 65818.0 53158.0 75935.0 54910.0 60951.0 True False 71589.99411541318 60249.32857321083 65611.2593742456 63831.775857423825 62885.01691873117 61702.3900552946 57888.95901930872 64200.99056270899 57812.430499013244 58817.12404204052 1.2171624383443678 1.02435012854669 1.1155128789933497 1.0852583647544378 1.0691617100112385 1.0490548638724972 0.9842194762520455 1.0915356982912028 0.9829183497256827 1.0 15.843948622602657 -1.5228787452803376 0.2806623646588988 1.010253881796128 2.1433837137376126 0.512924432602775 0.047404522808859165 46.59321065557808 0.6570852694930817 0.05054272356305863 25.910981242966823 0.029999999999999995 1.5228787452803376 1.1331298319414846 TGYES(ph)GEYEMLGEGLGVK ddPTM_PC-9_Lapatinib_30min_R1 1 TGYESGEYEMLGEGLGVK 18 0 F8VW18;F8W1I6;Q13561;Q13561-3;Q13561-2;H0YHL1;F8VX93;F8VRV7 F8VW18 DCTN2 Dynactin subunit 2 1 T(0.005)GYES(0.985)GEY(0.01)EMLGEGLGVK 92.427 0.0010023 2934400.0 25320.0 27080.0 31003.0 25104.0 26744.0 27002.0 23404.0 22081.0 25523.0 25179.0 True False 24958.932156880674 27017.297923790225 28454.05301504085 26950.231904489057 25170.970500727017 25847.18740473632 24615.744603348492 23106.96387065363 22648.33097089494 29531.156601091407 0.8451728624796987 0.9148743575722912 0.9635265356992232 0.9126033317466826 0.8523530195832815 0.8752514421931264 0.8335516598912603 0.7824605105307542 0.7669300351770816 1.0 14.849950240930976 -6.606554832048705 1.5858117812951007 0.8317419138289598 0.9123926848165435 0.12077411615423361 0.06618923724854733 0.5975842283447843 3.093594885270123 0.026792036209773818 0.027565667437772647 2.4742590529027375e-07 6.606554832048705 0.08065077098758366 TGYTLDVTTGQR ddPTM_PC-9_Lapatinib_30min_R1 2 TGYTLDVTTGQR 12 0 O43390-4;O43390;O43390-2;O60506-2;O60506;O60506-4;O60506-3;B7Z645;F6UXX1 O43390-4;O60506-2 HNRNPR;SYNCRIP Heterogeneous nuclear ribonucleoprotein R;Heterogeneous nuclear ribonucleoprotein Q 0 ; 144.17 0.00043165 11465400.0 34316.0 33189.0 32351.0 36479.0 37064.0 31001.0 38030.0 38077.0 36170.0 30241.0 False True 33826.64754721634 33112.1529096261 29691.225658471325 39161.78735037666 34883.96839062768 29675.159496860637 39999.00731778088 39846.19642692262 32096.153713014515 35468.116556400404 0.9537198710122132 0.9335751690387079 0.8371243962519738 1.1041405959096442 0.9835303302659494 0.8366714214912435 1.1277454570832817 1.1234370554624833 0.9049297461841852 1.0 15.114235101226962 -7.272045765600837 24.887206430854196 1.0493144779828694 0.9456661720317153 0.2072910143321426 0.09238209852684012 1097.85997525075 2576047.0818919013 0.038908076461927385 0.02654595111351581 5.345080304056405e-08 7.272045765600837 -0.10364830595115404 THAPSALS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 1 THAPSALSPPR 11 0 H9KVB4;O15417;O15417-2 H9KVB4 TNRC18 Trinucleotide repeat-containing gene 18 protein 1 THAPS(0.01)ALS(0.99)PPR 73.722 0.013619 10297000.0 7520.7 7653.1 9745.9 16053.0 12903.0 12393.0 9833.4 12566.0 11335.0 11078.0 True False 9912.126159722151 10126.814910472629 9616.662998142061 12352.228866377645 11111.641171992223 11618.063750877667 10708.553550180037 10624.213437953524 11934.144959138861 10690.162591880771 0.9272194014383334 0.9473022345014651 0.8995806111916353 1.155476239038611 1.0394267698446016 1.0867995365853127 1.0017203628234086 0.9938308558583256 1.1163670202923668 1.0 13.383996175425086 -5.738433224728683 24.999935799916305 1.054276685755673 0.9269608429474624 0.5835233138440894 0.05089223043127028 169.71132895537093 184417.49970151403 0.01364303601088502 0.023611053379545534 1.8262775281493817e-06 5.738433224728683 -0.1273158428082105 THCAATPSSSEDTETVSNS(ph)SEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 THCAATPSSSEDTETVSNSSEGR 23 0 H0YEM7;O75143-4;O75143-3;O75143-2;O75143;O75143-5 H0YEM7 ATG13 Autophagy-related protein 13 1 THCAATPSSSEDTET(0.006)VS(0.188)NS(0.619)S(0.188)EGR 126.93 1.8444000000000003e-07 0.0 1303.2 2861.1 4654.5 5391.3 5816.6 4989.3 4061.6 4020.1 5761.5 3669.0 True False 1523.8060206267367 3145.1310996488287 4765.480932289548 5089.242939830431 4676.878984812472 4727.652324839325 3676.8558445624626 3914.57663464804 5845.751037812874 4334.160656211981 0.3515804192543545 0.7256609408654561 1.0995164485791205 1.1742164962289112 1.0790737482491068 1.0907884362946647 0.8483432286462594 0.9031914008626865 1.348761963734406 1.0 12.081536916087341 -4.945171165685719 2.445847235056242 1.0615980862874506 0.30573978299661636 0.7448665532666632 0.1326916707323567 0.19539172165848084 1.8958511486958072 0.036404181369322976 0.27110286174165055 1.1345635693140782e-05 4.945171165685719 -0.7558583032908341 down THCVGDSQSSAS(ph)SPPATSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 THCVGDSQSSASSPPATSK 19 0 Q9H4Z2-2;Q9H4Z2 Q9H4Z2-2 ZNF335 Zinc finger protein 335 1 THCVGDSQSSAS(0.512)S(0.488)PPATSK 148.64 1.1317e-14 0.0 9751.0 9511.1 17381.0 16787.0 19392.0 20137.0 18310.0 14951.0 16232.0 13306.0 True False 11401.651708971227 10455.299151329895 17795.42895780956 15846.478814188315 15592.276806636779 19080.980270837503 16575.544247079633 14558.552091893935 16469.362292072994 15718.272469761947 0.7253756245099564 0.6651684637381935 1.1321491590149964 1.008156516224859 0.9919841278125473 1.2139362202522301 1.0545398216608641 0.9262183309203332 1.047784502002746 1.0 13.940155045220934 -5.255968761546947 24.994028270265307 1.0471121824270322 0.6952720040616406 0.7722607493306597 0.0763682974560383 200.31499060517984 915187.4197076007 0.020246594147861664 0.05038207731788971 5.5466560817450544e-06 5.255968761546947 -0.3518401783653916 THCVGDSQSSAS(ph)SPPATSK ddPTM_PC-9_Lapatinib_30min_R1 1 THCVGDSQSSASSPPATSK 19 0 Q9H4Z2-2;Q9H4Z2 Q9H4Z2-2 ZNF335 Zinc finger protein 335 1 THCVGDSQSS(0.004)AS(0.498)S(0.498)PPATSK 128.04 1.8147e-05 6008600.0 38064.0 24440.0 55563.0 37702.0 44294.0 53136.0 32293.0 40164.0 58718.0 33944.0 True False 37521.200379917325 24383.410681589125 50994.82461938246 40474.730850185086 41688.714005354566 50863.49714606583 33964.973529137475 42030.16606589072 52104.560512048294 39811.17517246304 0.9424790958160496 0.6124765364488629 1.2809173403817287 1.0166675732340857 1.0471611004889452 1.2776185813587226 0.8531517440015356 1.0557378897712755 1.308792324927109 1.0 15.280885838028729 -5.259603511780399 24.999572381076774 1.0989455905750274 0.7774778194655966 0.41149955979823327 0.1565398903544382 148.9493240072603 2028248.313959423 0.038822680643640944 0.09255907835296434 5.500428051082638e-06 5.259603511780399 -0.3214677711094308 THCVGDSQSSASS(ph)PPATSK ddPTM_PC-9_AZD4547_30min_R2 1 THCVGDSQSSASSPPATSK 19 0 Q9H4Z2-2;Q9H4Z2 Q9H4Z2-2 ZNF335 Zinc finger protein 335 1 THCVGDSQSSAS(0.035)S(0.965)PPATSK 166.91 4.4943e-08 8267000.0 10824.0 6979.9 23902.0 38124.0 27988.0 25786.0 17203.0 30604.0 18819.0 26427.0 True False 14265.806846813803 9236.016175616145 23585.04386271065 29335.100809928437 24102.349308046054 24173.597343672336 18734.033673373127 25874.85500995779 19813.73392025004 25501.798773752755 0.5594039453207754 0.36217116516197045 0.9248384426507635 1.1503149668062254 0.9451234997922163 0.9479173433268776 0.7346161672585535 1.0146286244164469 0.7769543668677581 1.0 14.63831139096489 -5.26988833743015 24.60836588094223 0.9384207670403135 0.4607875526396691 0.7187193252387882 0.11911191977580918 223.8933129019087 652111.6373261968 0.031257779984243395 0.06683531961660634 5.371698917472024e-06 5.26988833743015 -0.47763321440064443 THCVGDSQSSASS(ph)PPATSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 THCVGDSQSSASSPPATSK 19 0 Q9H4Z2-2;Q9H4Z2 Q9H4Z2-2 ZNF335 Zinc finger protein 335 1 THCVGDSQS(0.001)S(0.013)AS(0.063)S(0.923)PPATSK 120.66 0.000127 0.0 6491.0 7022.8 12443.0 13216.0 15043.0 14634.0 13829.0 12334.0 10699.0 10377.0 True False 7589.798096906187 7719.977171931699 12739.688310340282 12475.550366850113 12095.432137079053 13866.56727831534 12519.017006710234 12010.245568953238 10855.452634480594 12258.26795571319 0.6191574637074908 0.6297771593688863 1.0392731139804068 1.0177253762050171 0.9867162457842794 1.1312011883255149 1.0212712800812545 0.9797669305601729 0.8855617020038473 1.0 13.581467525932881 -5.2584448982336225 24.877403529707248 1.0114724529653667 0.6244672595935956 0.8771203806904155 0.057360788292009565 75.06600327503268 623620.9487804618 0.015568276809207018 0.037696737681868125 5.515121718802136e-06 5.2584448982336225 -0.3870051933717711 THDHQLESSLS(ph)PVEVFAK ddPTM_PC-9_AZD4547_30min_R2 4 THDHQLESSLSPVEVFAK 18 0 Q5JW53;Q9H410-4;Q9H410 Q5JW53 DSN1 Kinetochore-associated protein DSN1 homolog 1 THDHQLES(0.002)S(0.006)LS(0.992)PVEVFAK;THDHQLESS(0.008)LS(0.992)PVEVFAK;THDHQLES(0.001)S(0.005)LS(0.993)PVEVFAK;T(0.001)HDHQLES(0.022)S(0.042)LS(0.935)PVEVFAK 105.17 0.00030089 13340200.0 56828.0 52398.9 99103.0 134807.0 116602.0 107679.0 76716.0 107804.0 72263.0 111616.0 True False 74898.12190416988 69335.81970866238 97788.82946725 103729.32889738807 100413.82499702668 100945.81510778303 83543.57538141577 91145.36888947469 76082.67465216166 107708.35781326609 0.6953789234631235 0.6437366711028113 0.9079038196533127 0.9630573801637895 0.9322751459187044 0.937214317971431 0.775646171546457 0.8462237354643671 0.7063767027630868 1.0 16.71677067703869 -5.261217217925095 24.999991239907324 0.8807324521755183 0.6695577814646284 0.5057805713076328 0.08458998065456558 15.925614341534654 1791844.0789076868 0.02288222490962417 0.05333659846673884 5.480028057707012e-06 5.261217217925095 -0.2111746707108899 THDHQLESSLS(ph)PVEVFAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 THDHQLESSLSPVEVFAK 18 0 Q5JW53;Q9H410-4;Q9H410 Q5JW53 DSN1 Kinetochore-associated protein DSN1 homolog 1 T(0.001)HDHQLES(0.018)S(0.252)LS(0.729)PVEVFAK 59.918 0.015628 3230600.0 12395.0 13502.0 19594.0 22744.0 26100.0 21533.0 20801.0 20512.0 19759.0 18960.0 True False 14493.22868759085 14842.38932839063 20061.195270658805 21469.727417042883 20985.892360417674 20403.77157331996 18830.57869380139 19973.581734260486 20047.937994644544 22397.297912722588 0.6470971964594934 0.6626866055998453 0.8956971215381843 0.9585856070989346 0.9369832219134265 0.9109925515492552 0.8407522535611247 0.8917853310740073 0.8951052074570339 1.0 14.45103707062442 -5.265200136214993 4.840829705571438 0.9128457693091797 0.6502641592586912 0.870809709374154 0.04031969463830924 0.0576422084985091 4.077860940412157 0.01093435135163255 0.026910711806433875 5.430000427555871e-06 5.265200136214993 -0.2625816100504885 THDHQLESSLS(ph)PVEVFAK ddPTM_PC-9_Lapatinib_30min_R1 3 THDHQLESSLSPVEVFAK 18 0 Q5JW53;Q9H410-4;Q9H410 Q5JW53 DSN1 Kinetochore-associated protein DSN1 homolog 1 THDHQLES(0.001)S(0.004)LS(0.995)PVEVFAK;THDHQLESS(0.003)LS(0.997)PVEVFAK;THDHQLESS(0.008)LS(0.991)PVEVFAK 105.92 0.00028576 6476000.0 62349.0 45389.1 70841.0 54864.0 69209.0 68395.0 55008.0 55752.0 72951.0 58351.7 True False 61459.89182659374 45284.00432764796 65016.726434167984 58898.88158093875 65138.26269012931 65469.90528653218 57856.0450837889 58342.441452682455 64734.49017191375 68437.71359624711 0.8980412786607762 0.6616820163631414 0.9500131289852629 0.8606202411789596 0.9517889956759349 0.9566348997685149 0.8453824951709306 0.8524896345438658 0.9458891416773393 1.0 16.062503941854047 -1.5228787452803376 0.1753904557551609 0.9693488751626306 0.2699668698338215 0.22271694865794867 0.08055627370260961 90.96657799698824 1.006646610540352 0.19525589462237236 16.83107213353724 0.029999999999999995 1.5228787452803376 -0.6993820053288091 THEAQIQEMR ddPTM_PC-9_AZD4547_30min_R2 2 THEAQIQEMR 10 0 P35579 P35579 MYH9 Myosin-9 0 ; 77.062 0.015118000000000001 4517400.0 10521.9 7225.6 13063.7 13829.5 15418.099999999999 11797.0 8494.8 12744.6 8713.6 12171.5 False True 13867.645330884165 9561.133895690775 12890.46680233006 10641.322438645084 13277.562950778363 11059.331725095117 9250.820743391847 10775.214911773232 9174.183106833027 11745.37948971627 1.1806894228514333 0.8140336294848606 1.0974925768568293 0.9060007339875353 1.1304498898825368 0.9415899873459325 0.7876136102278732 0.9174003207991304 0.7810886923547709 1.0 13.519805706700074 -7.001111931979326 24.964137283661085 0.8646365460298561 1.0137782856633122 0.2801653107018248 0.11576426862707909 52.27654338180767 1173697.9653117536 0.03792124213917574 0.033016585212324444 9.974429568186569e-08 7.001111931979326 0.14914173963345612 THEAQIQEMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 THEAQIQEMR 10 0 P35579 P35579 MYH9 Myosin-9 0 ;; 85.845 0.0079013 11963900.0 13297.1 12213.2 13632.4 17297.7 16545.8 14447.800000000001 15283.5 12514.900000000001 9107.8 11211.6 False True 15548.036400303688 13425.645781773119 13957.44811716491 16328.565948900057 13303.76926501912 13690.131934101693 13835.736237042152 12186.397135632633 9240.984344735232 13244.174329023232 1.1739528651651603 1.0137019830939715 1.0538556629067175 1.232886667243401 1.0044997094205632 1.033671982412765 1.044665820104963 0.920132643446667 0.6977395581757464 1.0 13.693070285276345 -7.816604255970537 2.9029703765568646 0.8384068142723253 1.0805541989117449 0.502439299640288 0.09604750428583132 0.20299487470887287 3.4124589495447193 0.059252313853604535 0.025774256465665654 1.525442155885235e-08 7.816604255970537 0.24214738463941954 THEAQIQEMR ddPTM_PC-9_Lapatinib_30min_R1 5 THEAQIQEMR 10 0 P35579 P35579 MYH9 Myosin-9 0 ;;;; 80.834 0.011611 21269100.0 27929.7 24414.699999999997 26500.4 22817.0 24187.0 22313.2 26435.9 22149.199999999997 25130.6 19618.2 False True 27531.417356320322 24358.16926218469 24321.639406502218 24495.0382952807 22764.368213471615 21358.916450609697 27804.621550147873 23178.332691629974 22300.12719105012 23009.179730391676 1.1965405841893377 1.0586283191143577 1.0570406981686957 1.064576772501213 0.9893602675198064 0.9282780481912517 1.208414288381699 1.0073515424374244 0.9691839279952686 1.0 14.489921932429585 THLPGFVEQAEALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 THLPGFVEQAEALK 14 0 P30044-2;P30044 P30044-2 PRDX5 Peroxiredoxin-5, mitochondrial 0 85.287 0.005836 4364400.0 55476.0 44704.0 51059.0 55856.0 67561.0 54807.0 49903.0 51031.0 48200.0 44698.0 False True 64866.991099055274 49141.91768155647 52276.44020233578 52726.569407595285 54322.90704069649 51932.824437790674 45175.82657356717 49691.490321813864 48904.83381455878 52801.3935708267 1.2285090735729167 0.9306935737527177 0.9900579637583474 0.9985829130980975 1.0288157824438642 0.9835502611901531 0.8555801943554623 0.9411018717746289 0.9262034675080846 1.0 15.688288386239037 -7.019900121242829 6.487837664678118 0.9246656425670197 1.023427595406014 0.2709953841458559 0.0794678592365002 0.23918923673236475 40.95347526728483 0.028862266797728135 0.023362917335240912 9.552122398405131e-08 7.019900121242829 0.09876195283899425 THNDIIHNENMR ddPTM_PC-9_AZD4547_30min_R2 5 THNDIIHNENMR 12 0 P15311;E7EQR4 P15311 EZR Ezrin 0 ;;;; 126.71 0.00010752 69665600.0 69488.4 50437.7 86300.3 125079.9 110343.2 91654.5 75960.3 111872.9 72397.0 98240.8 False True 91584.26575149065 66740.70016201877 85155.9016343858 96244.66152019128 95023.95134227493 85923.32962598362 82720.61954540049 94585.51388849539 76223.75761859509 94801.41949417237 0.9660642872243123 0.7040052830234409 0.8982555544922035 1.0152238440491668 1.0023473472157898 0.9063506652583984 0.87256730950622 0.9977225488096173 0.8040360368578734 1.0 16.532621040802425 -5.514189460573405 24.902876985582513 0.9418157940723317 0.8265586870321565 0.19535603927671885 0.08664947580197464 522.6599267900532 1497903.7931744591 0.02220985483422644 0.04116595407355423 3.0606279462466644e-06 5.514189460573405 -0.11525710704017522 THNDIIHNENMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 THNDIIHNENMR 12 0 P15311;E7EQR4 P15311 EZR Ezrin 0 ;;;;;; 84.169 0.005556800000000001 57487700.0 140231.3 99834.8 145631.8 171419.9 212991.8 162829.0 153958.7 169216.1 144231.8 134978.7 False True 163969.68939557567 109745.73915879255 149104.2144236772 161815.79875381445 171257.5857644294 154289.96059592778 139374.6173715383 164774.35667427853 146340.9172152422 159449.26981919853 1.0283502055638316 0.6882799732054877 0.9351200829752828 1.0148418925799996 1.0740568831617758 0.9676429423030852 0.8741000666204172 1.0333967465709826 0.9177898235669562 1.0 17.282737965375162 -5.511707367887857 24.281247244525083 0.9824863111383498 0.8466613175058889 0.2193272356528776 0.09304821138280983 450.48466118892406 979135.7746363531 0.023700066493901772 0.045043906805958274 3.0781702190408893e-06 5.511707367887857 -0.13582499363246092 THNDIIHNENMR ddPTM_PC-9_Lapatinib_30min_R1 7 THNDIIHNENMR 12 0 P15311;E7EQR4 P15311 EZR Ezrin 0 ;;;;;; 122.55 0.00022065 84452500.0 246345.1 163478.0 190997.4 197274.1 175447.9 166636.8 122456.6 123939.4 175866.09999999998 123239.4 False True 242832.17369984195 163099.47673505862 175294.33104328488 211782.29540110624 165128.3994658428 159510.13251335328 128796.80356325429 129698.07698702473 156058.2078658661 144541.166083822 1.6800208568887514 1.128394637694249 1.2127640574148169 1.4652040047766732 1.1424316265034276 1.1035619597869475 0.8910735055822279 0.8973089155224506 1.0796800115433216 1.0 17.141120912815865 -6.676468835091986 1.896741821870016 0.9639241955938582 1.3428835527562166 0.5750174652863003 0.15208126972553143 0.255250567901558 1.8887897716145903 0.05957958264940678 0.058000238579464125 2.106353045152149e-07 6.676468835091986 0.3789593571623584 THS(ph)EGSLLQEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 THSEGSLLQEPR 12 0 P49796-1;P49796-4;P49796-6;P49796;C9J582 P49796-1 RGS3 Regulator of G-protein signaling 3 1 T(0.065)HS(0.909)EGS(0.026)LLQEPR 81.327 0.0075513 3942700.0 7933.9 12889.0 13215.0 12975.0 18610.0 15528.0 16931.0 14668.0 13514.0 11088.0 True False 9276.952568332157 14168.5347395665 13530.095718166587 12248.05281551756 14963.504093002808 14713.68434451828 15327.17311017507 14282.980542030658 13711.616684023806 13098.166627440298 0.7082634411519241 1.0817189262109255 1.0329763014177427 0.9350967325349356 1.1424121038172381 1.1233392247197036 1.170176983247798 1.0904564698473302 1.0468348032234027 1.0 13.677077268976012 -4.760691821668107 24.9840286610148 1.0738591612962762 0.708263015656192 0.7273947724669478 0.06623750412231345 10.017900555515977 334585.0897872867 0.017655296268568658 0.10288230267329514 1.7350347535427406e-05 4.760691821668107 -0.36559614564008425 THS(ph)EGSLLQEPR ddPTM_PC-9_Lapatinib_30min_R1 1 THSEGSLLQEPR 12 0 P49796-1;P49796-4;P49796-6;P49796;C9J582 P49796-1 RGS3 Regulator of G-protein signaling 3 1 T(0.07)HS(0.912)EGS(0.017)LLQEPR 80.387 0.008132200000000001 8775500.0 10118.0 12993.0 16493.0 16823.0 19732.0 21794.0 18214.0 18444.0 21916.0 19925.0 True False 9973.715464586041 12962.915506787536 15137.009204821106 18060.219539882863 18571.4025546046 20861.921424295375 19157.031798213542 19300.975573132357 19447.589294288817 23369.009701606374 0.42679238837837674 0.5547053842806386 0.6477385819126343 0.7728277650824635 0.7947021628960174 0.892717393277531 0.8197622425094332 0.8259218434834069 0.8321956960355064 1.0 14.51230897850319 -4.575292958126993 0.5147558570704607 0.8831087031398802 2.2060700273785968e-13 0.9093814606941865 0.04810643669822567 1.4743754792827641 0.2564930335808627 0.02864667797515341 0.8227436620503256 2.658930843621127e-05 4.575292958126993 -0.8831087031396596 down THS(ph)FENVSCHLPDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 THSFENVSCHLPDSR 15 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 T(0.209)HS(0.791)FENVSCHLPDSR 102.24 0.00086003 7863900.0 38028.0 50691.0 46501.0 54689.0 51182.0 33672.0 56290.0 35426.0 37484.0 42920.0 True False 44465.389312763575 55723.267474851906 47609.76019602455 51624.95263413026 41153.25451306124 31906.181043831748 50957.803695691575 34496.10503694968 38032.13258723903 50701.05624546692 0.8770111040189451 1.0990553570535133 0.9390289615570139 1.0182224288225938 0.8116843624286559 0.6293001252155258 1.0050639467742373 0.6803823744802932 0.7501250546558269 1.0 15.629728182482681 -6.286638331271627 8.51694416409792 0.7969977622370221 0.9884474214464868 0.30349384644613076 0.12514296685422144 0.3200494524876563 100.02096708180505 0.03687791771564052 0.04250920363813392 5.16846606012717e-07 6.286638331271627 0.19144965920946466 THS(ph)FENVSCHLPDSR ddPTM_PC-9_Lapatinib_30min_R1 2 THSFENVSCHLPDSR 15 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 T(0.182)HS(0.818)FENVSCHLPDSR;T(0.261)HS(0.739)FENVSCHLPDSR 126.04 1.4013e-05 6083700.0 80031.0 93646.0 126219.0 98689.0 134721.0 124647.0 105773.0 102470.0 130612.0 94716.0 True False 78889.74326411221 93429.16844059326 115841.76103942981 105946.91827685325 126796.97565167685 119316.13837634865 111249.40838873619 107231.13028512655 115901.1011546656 111087.53439886332 0.7101583781746031 0.8410409767952258 1.0427971209037397 0.9537246357133777 1.141414978177554 1.074073153410177 1.0014571751074397 0.9652849967855959 1.0433312952875433 1.0 16.761337409346197 -5.0235377160336725 2.1158315277487136 1.0308907321901934 0.6885247480694867 0.798055498244554 0.05253718925172608 0.18575313809433772 1.333078887186233 0.014941569212295584 0.10078197049885192 9.472449180374314e-06 5.0235377160336725 -0.34236598412070673 THS(ph)QGGYGSQGYK ddPTM_PC-9_AZD4547_30min_R2 2 THSQGGYGSQGYK 13 0 K7ERS0;K7EPH2;K7ER00;Q9Y285-2;Q9Y285 K7ERS0 FARSA Phenylalanine--tRNA ligase alpha subunit 1 T(0.21)HS(0.79)QGGYGSQGYK;T(0.23)HS(0.77)QGGYGSQGYK 91.31700000000001 0.0029323 27248000.0 68788.0 68990.0 124459.0 191772.0 150981.0 134608.0 100861.0 135659.0 106603.0 134645.0 True False 90661.15312071578 91289.66832701868 122808.592339934 147561.9282478647 130019.89427176284 126190.94048076643 109837.4336063526 114696.01868369714 112237.81694566226 129931.11953274847 0.6977631951971683 0.7026004905930914 0.9451822841330996 1.1356935026691006 1.000683244624795 0.9712141397270162 0.8453512445774674 0.8827447889016965 0.8638255203933134 1.0 16.987387483503348 -5.2655470303923355 6.480328068127769 0.9564775682840215 0.6985662291301501 0.6253318184138221 0.07911456135544277 0.09386029851969131 22.150055165733452 0.02334664463333838 0.05476276710685943 5.425664928188752e-06 5.2655470303923355 -0.25791133915387143 THS(ph)QGGYGSQGYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 THSQGGYGSQGYK 13 0 K7ERS0;K7EPH2;K7ER00;Q9Y285-2;Q9Y285 K7ERS0 FARSA Phenylalanine--tRNA ligase alpha subunit 1 T(0.493)HS(0.507)QGGYGSQGYK;T(0.056)HS(0.944)QGGYGSQGYK 99.39200000000001 0.0014272 12472200.0 58488.0 63524.0 52640.0 100827.0 94363.0 72188.0 82735.0 95327.0 76656.0 57646.0 True False 68388.86320934368 69830.24290450948 53895.13723831167 95177.99007554428 75873.2475404635 68402.33420028884 74897.74185047152 92824.76725730527 77776.9489810957 68096.76347451504 1.0042894804381994 1.0254561206957093 0.7914493213540423 1.3976874262337635 1.1141975575514507 1.0044873017480214 1.0998722704127004 1.3631303827243506 1.1421533860446016 1.0 16.055298610529416 -5.748674704808824 24.999977710119904 1.1644280502055309 0.9489041558647074 0.3504858805894082 0.13690027774355829 269.2474951973247 527324.3078693663 0.037712648531994325 0.06477831448530685 1.7837143046489318e-06 5.748674704808824 -0.21552389434082342 THS(ph)QGGYGSQGYK ddPTM_PC-9_Lapatinib_30min_R1 1 THSQGGYGSQGYK 13 0 K7ERS0;K7EPH2;K7ER00;Q9Y285-2;Q9Y285 K7ERS0 FARSA Phenylalanine--tRNA ligase alpha subunit 1 T(0.2)HS(0.8)QGGYGSQGYK 95.9 0.0019264 8181800.0 41175.0 43361.0 50753.0 39579.0 44656.0 46127.0 35170.0 44771.0 56050.0 39853.0 True False 40587.836949429795 43260.60026859189 46580.284252245554 42489.77169167354 42029.42187707395 44154.25573728883 36990.93051186837 46851.22410457106 49737.05876733381 46741.53794921547 0.8683462019056444 0.9255279600682885 0.9965500986051183 0.9090366632317177 0.8991878256710077 0.9446470457446713 0.7913930977636828 1.0023466526812783 1.0640869117608618 1.0 15.512417583828578 -7.980468855538574 24.99795131320129 1.032434613164276 0.9097412644364297 0.5211744328714776 0.05185459521058396 176.05803225516206 225336.9188739892 0.02829991377488794 0.01359197665148153 1.0459986992404596e-08 7.980468855538574 -0.12269334872784643 THS(ph)TSSSLGSGESPFSR ddPTM_PC-9_AZD4547_30min_R2 1 THSTSSSLGSGESPFSR 17 0 F8WBF9;Q5TH30;Q9UGV2-3;Q9UGV2-2;Q9UGV2 F8WBF9 NDRG3 Protein NDRG3 1 T(0.278)HS(0.343)T(0.343)S(0.032)S(0.003)S(0.001)LGSGESPFSR 58.163999999999994 0.024436000000000003 123290000.0 23167.0 15509.0 46802.0 82986.0 51015.0 49518.0 30167.0 51712.0 30000.0 40814.0 True False 30533.62409646486 20521.980954975108 46181.37490011642 63854.859820919075 43932.44783299881 46421.631632047094 32851.80455877735 43721.098623543905 31585.738753786125 39385.11428281474 0.7752579788701507 0.5210593222508344 1.1725591188716482 1.6212942626595712 1.1154581783749768 1.1786593101826457 0.8341172840803937 1.1100919578293853 0.8019714892021581 1.0 15.265362841509653 -5.266988258283379 24.95870424478326 1.120074146489482 0.6481586384883763 0.4044366166372316 0.22072979026286468 400.522987316277 1801548.9293530693 0.061113467896507324 0.13323766699027653 5.407689431402156e-06 5.266988258283379 -0.4719155080011056 THS(ph)TSSSLGSGESPFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 THSTSSSLGSGESPFSR 17 0 F8WBF9;Q5TH30;Q9UGV2-3;Q9UGV2-2;Q9UGV2 F8WBF9 NDRG3 Protein NDRG3 1 T(0.201)HS(0.661)T(0.13)S(0.006)S(0.001)SLGSGESPFSR 61.138999999999996 0.018799 13551000.0 2290.2 2002.7 9800.8 10462.0 27053.0 27337.0 18649.0 22746.0 30314.0 14665.0 True False 2677.885626488144 2201.514820616792 10034.48824174098 9875.848058261636 21752.158851585435 25903.399595961873 16882.431712932183 22148.94160137913 30757.28490154638 17323.648411923867 0.15457977227504546 0.12708147661906422 0.5792364289057172 0.5700789939528033 1.2556338211420537 1.4952623708371133 0.9745309597320161 1.2785379311977962 1.775450769387362 1.0 14.080455177483115 -5.967708754445064 1.3074913784987687 1.3276192535869138 0.15324556236413286 0.7944782119754236 0.2384456327961397 0.1948821354765544 0.6762913296705503 0.08687872785351812 0.16732186313745342 1.0771873523391034e-06 5.967708754445064 -1.174373691222781 down THSAGTS(ph)PTITHQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 THSAGTSPTITHQK 14 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 T(0.015)HS(0.049)AGT(0.207)S(0.727)PT(0.001)ITHQK;T(0.003)HS(0.01)AGT(0.28)S(0.706)PT(0.001)ITHQK 62.468999999999994 0.041551 4905100.0 30925.0 35182.0 38326.0 42985.0 40614.0 29687.0 29026.0 25036.0 21666.0 19758.7 True False 36159.99170340837 38674.63645026213 39239.83719216443 40576.6898092503 32655.978250038454 28130.16145902332 26276.447149958145 24378.83152783471 21982.82426195499 23340.79590021685 1.549218452446706 1.6569544849969242 1.6811696293441247 1.7384449948801155 1.3990944606021365 1.2051928982748172 1.1257733996000547 1.0444730176321115 0.9418198229371757 1.0 14.510566136041097 -6.754932194718565 1.4458247679461866 1.0181142368009237 1.66345168916862 0.9490553055108203 0.06573121306080335 0.08589799791729175 0.3744384764954817 0.03177793169794195 0.028922596633020093 1.7581980954816207e-07 6.754932194718565 0.6453374523676962 THSLLLLLLLT(ph)LLGLGLVQPSYGQDGMYQR ddPTM_PC-9_Lapatinib_30min_R1 1 THSLLLLLLLTLLGLGLVQPSYGQDGMYQR 30 0 P34096 P34096 RNASE4 Ribonuclease 4 1 T(0.023)HS(0.024)LLLLLLLT(0.942)LLGLGLVQPS(0.001)Y(0.002)GQDGMY(0.007)QR 46.772 0.020063 3782400.0 6353.7 14075.0 7610.3 10069.0 15771.0 20829.0 29112.0 26928.0 25217.0 26669.0 True False 6263.09507287412 14042.410202265428 6984.610510607539 10809.507849199339 14843.38078697898 19938.192224770493 30619.27691388999 28179.173185497086 22376.795913217775 31278.701115791213 0.20023513923064293 0.44894479953888 0.22330244739866525 0.3455868518703324 0.47455233937080665 0.6374367065614689 0.9789177881952295 0.9009061175903716 0.7154004199337016 1.0 14.932892983859869 -6.822538521148083 1.7264779226892395 0.8927382256298373 0.3102256788213738 0.8750191033738841 0.10081872436235453 0.11704234579415623 0.7202638446574016 0.04277580434471906 0.0372431094962491 1.5047400451175808e-07 6.822538521148083 -0.5825125468084635 down THSTSS(ph)SLGSGESPFSR ddPTM_PC-9_AZD4547_30min_R2 1 THSTSSSLGSGESPFSR 17 0 F8WBF9;Q5TH30;Q9UGV2-3;Q9UGV2-2;Q9UGV2 F8WBF9 NDRG3 Protein NDRG3 1 THST(0.001)S(0.185)S(0.813)S(0.001)LGSGESPFSR 226.7 4.8301e-29 77506000.0 6254.9 6984.2 14720.0 22466.0 18044.0 16815.0 9777.2 13695.0 11860.0 14653.0 True False 8243.828089997754 9241.70606652506 14524.803182122865 17286.810796239955 15538.902062111736 15763.555391834736 10647.351859053864 11578.752429792565 12486.895387330116 14140.002930026087 0.58301459559758 0.6535858664428161 1.027213590690258 1.2225464790768656 1.098932025616141 1.1148198108474972 0.7529950249475812 0.8188649243632938 0.8830900141338994 1.0 13.787494798645394 -5.218201824065189 5.412826496181951 0.9917438236920525 0.6086325307285491 0.5493327601801639 0.1348020967065193 0.1700439014216299 12.611377483264349 0.040191315713915945 0.10816713601884428 6.050596278630044e-06 5.218201824065189 -0.38311129296350344 THSTSS(ph)SLGSGESPFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 THSTSSSLGSGESPFSR 17 0 F8WBF9;Q5TH30;Q9UGV2-3;Q9UGV2-2;Q9UGV2 F8WBF9 NDRG3 Protein NDRG3 1 T(0.013)HS(0.001)T(0.204)S(0.024)S(0.578)S(0.141)LGS(0.04)GESPFSR;THS(0.012)T(0.121)S(0.121)S(0.724)S(0.004)LGS(0.018)GESPFSR 217.79 1.7641999999999997e-22 61168000.0 10763.900000000001 13652.900000000001 20993.4 26792.4 43599.0 53364.0 43002.0 42898.0 44486.0 32178.0 True False 12586.015673284326 15008.269683127277 21493.962273912864 25291.30869013278 35056.088928040255 50565.49789804699 38928.539252480565 41771.972954188095 45136.523590756486 38011.61667909216 0.3311097178407335 0.39483376384205193 0.5654577245522778 0.6653573538755578 0.9222467232582201 1.330264332741731 1.0241221672082352 1.098926502043894 1.1874402494325713 1.0 15.214152765583554 -6.079311508157016 1.3785736596373608 1.1317842915312781 0.3805253758227768 0.903345841967075 0.10102638220909821 0.119723570842201 0.46000701235190417 0.03737115630705961 0.062326334280916364 8.330834211550974e-07 6.079311508157016 -0.7512589157085013 down THSVETPYGSVT(ph)FT(ph)VYGT(ph)PKPKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 THSVETPYGSVTFTVYGTPKPKR 23 2 Q9UN36-6;Q9UN36-2;Q9UN36-5;Q9UN36-4;A0A0A0MS87;G3V271;G3V4S9;G3V5H8;G3V5G0;G3V392;H7C0X0;G3V5B7;G3V5D7;G3V239;G3V285;G3V4S2;G3V5V9;G3V280;G3V5A6;G3V237;G3V3X3;G3V5G7;G3V2Y3;G3V3C3;G3V420;G3V3X2 Q9UN36-6 NDRG2 Protein NDRG2 3 THS(0.002)VET(0.005)PY(0.006)GS(0.006)VT(0.987)FT(0.987)VY(0.472)GT(0.535)PKPKR 50.397 0.03312 0.0 7779.1 7676.1 11349.0 9929.6 11123.0 12197.0 8753.1 7435.4 10500.0 7936.5 True False 9095.947985771514 8438.13247842241 11619.603201322174 9373.276704197555 8943.5279971236 11557.367848408652 7923.943001043846 7240.228628457509 10653.542635951597 9375.324624700574 0.9702008570249393 0.9000362991368851 1.2393814258664433 0.9997815627100929 0.9539432878474046 1.2327432180811304 0.8451913206468751 0.7722643127878621 1.1363385335888405 1.0 13.194652929967294 -7.314440382892207 24.99954011931435 0.9194705972211846 1.0446100885749436 0.12779384567536034 0.13809497845920543 641.3255645628676 302498.446054409 0.05724420242425842 0.038594060889131775 4.847966577732187e-08 7.314440382892207 0.125139491353759 THT(ph)GERPNACADCGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 THTGERPNACADCGK 15 1 Q6DD87 Q6DD87 ZNF787 Zinc finger protein 787 1 T(0.089)HT(0.911)GERPNACADCGK 77.027 0.0096176 2490700.0 7664.8 6913.5 6287.2 7445.5 8149.4 4610.3 5923.8 5667.3 4486.1 5249.4 True False 8962.299253299421 7599.82659027023 6437.110692338781 7028.352773636687 6552.58357095739 4368.527752030694 5362.65477940199 5518.539380000704 4551.700725632618 6201.074665772467 1.4452816223561775 1.2255660510295632 1.0380637291579702 1.1334088287035915 1.0566851592878113 0.7044791407114119 0.8647944216833526 0.8899327418940635 0.7340180486386085 1.0 12.598302545424001 -4.656560674916529 0.5072432626360152 0.8312332888293412 1.9041455117160457 0.7503357098852308 0.10707739556475875 2.507211820538219 0.45166260900974503 0.06781740306989158 1.6510076843788997 2.205156034377392e-05 4.656560674916529 1.0729122228867045 THTRVS(ph)VQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 THTRVSVQR 9 1 H0YEN5;P15880;E9PQD7 H0YEN5 RPS2 40S ribosomal protein S2 1 THTRVS(1)VQR 58.781000000000006 0.036306 61446000.0 9334.5 9180.0 8452.2 12734.0 11358.0 11549.0 8446.3 16552.0 9753.6 10294.0 True False 10914.646485221203 10091.329731493566 8653.732503146997 12020.555264185026 9132.481434085214 10943.350109147454 7646.205318083494 16117.527538293645 9896.227948001671 12160.22071274083 0.897569768103421 0.8298640271323703 0.7116427166556343 0.9885145630284926 0.7510128023019095 0.8999302206481825 0.6287883664868195 1.3254305097773893 0.8138197637838047 1.0 13.569881794045331 -7.74854710275979 24.999984120180073 1.052218966206434 0.819343564801504 0.32914239573930615 0.15103930620100348 235.43289213825733 456540.2479624189 0.06580586692493223 0.03768386897877453 1.7842384629098492e-08 7.74854710275979 -0.23287540140493002 THVEKEDGEAR ddPTM_PC-9_AZD4547_30min_R2 2 THVEKEDGEAR 11 1 G3V3A4;Q13573;G3V4X8 G3V3A4 SNW1 SNW domain-containing protein 1 0 ; 68.626 0.016555 5946700.0 31101.0 19635.5 26034.0 30834.0 27439.0 26960.0 19460.8 20221.6 31012.0 32811.0 False True 40990.47105901298 25982.291381869476 25688.772149686585 23725.697680551195 23629.568481616276 25274.18693808292 21192.773499434967 17096.816366140454 32651.23100774719 31662.296876891123 1.294614576396385 0.8206066503290471 0.8113363427034145 0.7493359617213212 0.746299883848996 0.7982423712453218 0.6693378431083631 0.5399739770180301 1.03123380892742 1.0 14.950478296196524 -4.748465289609764 3.721897198509958 0.7711680768086022 1.3711802566640532 0.5402744501822629 0.13688079855595536 0.21871817701486568 5.040469407595775 0.03292223844705602 0.38119653260874675 1.7845746125166923e-05 4.748465289609764 0.600012179855451 THVEKEDGEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 THVEKEDGEAR 11 1 G3V3A4;Q13573;G3V4X8 G3V3A4 SNW1 SNW domain-containing protein 1 0 ; 65.719 0.019821000000000002 3463900.0 19545.2 19247.5 17667.2 21023.3 33647.0 30850.0 17931.8 27603.0 23941.0 30200.0 False True 22853.81632470356 21158.26459770395 18088.45305122911 19845.432659458213 27054.11188701048 29232.17169167884 16233.17008901052 26878.450497796017 24291.091833077833 35675.02093693154 0.6406111538128013 0.5930834528481093 0.5070341257320344 0.5562837004228299 0.7583488720255659 0.8194016688415471 0.45502902766920583 0.7534249396885672 0.6808991612372448 1.0 15.122626655938602 -14.522878745251363 0.17511905958172275 2.458535774348127 0.5592667724137163 0.528045980178485 0.10602257533647876 110.26203255298746 1.0483232635613928 55.72298291801012 0.367602566402866 3.0000000002001477e-15 14.522878745251363 -1.8992690019344107 THVEKEDGEAR ddPTM_PC-9_Lapatinib_30min_R1 1 THVEKEDGEAR 11 1 G3V3A4;Q13573;G3V4X8 G3V3A4 SNW1 SNW domain-containing protein 1 0 52.167 0.045614999999999996 2473200.0 20805.0 18424.0 19256.0 16384.0 19685.0 12836.0 17093.0 20629.0 22538.0 16933.0 False True 20508.316884830263 18381.34035996718 17672.846010309535 17588.93401542179 18527.167002199058 12287.034202177445 17977.991903308663 21587.498649867026 19999.533104338447 19859.846488195748 1.0326523368153904 0.9255529931156639 0.889878278808141 0.885653070172333 0.9328957811034035 0.6186872697873362 0.9052432461647869 1.0869922213496543 1.0070336201352676 1.0 14.277566850775521 -7.663819455703324 6.349433620221639 1.0341723878232818 0.8763011721273303 0.30906010404894624 0.10082475112571997 0.25783450872480534 14.088142391366214 0.0506507683498869 0.028776842596502813 2.168605447088093e-08 7.663819455703324 -0.15787121569595153 THYDPPR ddPTM_PC-9_Lapatinib_30min_R1 1 THYDPPR 7 0 P31943;G8JLB6;E9PCY7;P55795;D6RBM0;H0YB39;H0YBD7;E5RGV0;E7EN40 P31943 HNRNPH1;HNRNPH2 Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;Heterogeneous nuclear ribonucleoprotein H2 0 89.369 0.013969999999999998 4966500.0 31005.0 32350.0 30480.0 30483.0 32660.0 30329.0 27516.0 24996.0 27398.0 25726.0 False True 30562.863014379345 32275.09556257809 27974.052056202487 32724.821508307028 30739.003012030527 29031.899370352126 28940.643843177975 26157.405412384313 24312.148726269606 30172.704822259726 1.0129308324997028 1.069678563877619 0.9271310683278485 1.08458362288304 1.0187685589709883 0.9621908125695785 0.9591663728412971 0.8669227888739642 0.8057663000213845 1.0 14.880956411756575 -7.32172339893092 1.6297024587108757 0.8805131538147205 1.0216298983278085 0.44089517662528366 0.06156676287527628 0.32746703857213666 1.6913858203214063 0.03459555762324568 0.019954328318922118 4.767345211589329e-08 7.32172339893092 0.14111674451308798 THYDPPRK ddPTM_PC-9_AZD4547_30min_R2 2 THYDPPRK 8 1 P31943;G8JLB6;E9PCY7;P55795;D6RBM0;H0YB39;H0YBD7;E5RGV0;E7EN40 P31943 HNRNPH1;HNRNPH2 Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;Heterogeneous nuclear ribonucleoprotein H2 0 ; 60.972 0.026864999999999997 5815900.0 18484.4 15085.6 23199.4 28293.3 32836.6 23886.3 17875.7 26326.0 25519.43 22844.4 False True 24362.054700595458 19961.72518501338 22891.760797781317 21770.716812127477 28277.804890974177 22392.685884982584 19466.602670180546 22257.92161129751 26868.33497085108 22044.624509294197 1.105124502815832 0.9055144113068176 1.038428247581625 0.9875748531325068 1.2827528488431281 1.0157889455337124 0.8830544000408473 1.0096756967628722 1.2188157235122405 1.0 14.428139282985635 THYDPPRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 THYDPPRK 8 1 P31943;G8JLB6;E9PCY7;P55795;D6RBM0;H0YB39;H0YBD7;E5RGV0;E7EN40 P31943 HNRNPH1;HNRNPH2 Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;Heterogeneous nuclear ribonucleoprotein H2 0 54.205 0.037413 1919200.0 7448.6 6452.1 5788.0 9043.3 9941.4 8365.0 8875.7 8637.9 9133.1 6555.2 False True 8709.500863444062 7092.621847556601 5926.007871112238 8536.633219774183 7993.454034937024 7926.324674259107 8034.929441496714 8411.164277611575 9266.654309372336 7743.60586906535 1.1247345242914972 0.9159327020878811 0.7652775685273229 1.1024106035505847 1.0322650933035968 1.0235960879573809 1.0376211776990307 1.0862076944299335 1.1966846539015314 1.0 12.918789809431736 -5.844429282357526 24.99945856035518 1.067335934569592 0.9332695590015637 0.28763638250270107 0.09594770589276475 33.32304223299386 10034.363107625717 0.027522146987152336 0.04082195865126754 1.4307729394599841e-06 5.844429282357526 -0.13406637556802836 THYDPPRK ddPTM_PC-9_Lapatinib_30min_R1 3 THYDPPRK 8 1 P31943;G8JLB6;E9PCY7;P55795;D6RBM0;H0YB39;H0YBD7;E5RGV0;E7EN40 P31943 HNRNPH1;HNRNPH2 Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;Heterogeneous nuclear ribonucleoprotein H2 0 ;; 68.78699999999999 0.016921000000000002 9054000.0 38132.200000000004 29995.9 22612.3 21431.4 30309.9 24966.5 22943.399999999998 28261.4 27599.0 21253.4 False True 37588.42783541097 29926.446336492598 20753.203980002196 23007.5366490546 28527.13127355616 23898.740994754073 24131.296989081613 29574.527817313097 24490.509989645794 24927.021871624624 1.5079389759833006 1.2005624454704318 0.8325585016486208 0.9229958062196332 1.1444259735668494 0.9587483461856676 0.9680778198598681 1.186444492632267 0.9824884061871937 1.0 14.605422908279797 -4.895951874438887 3.3695428072303746 1.0058395358101198 1.519479003692228 0.7190169250615547 0.09792053809650227 0.1431043164951562 2.819930369321879 0.025760521948260288 0.16140835221082947 1.27071490939182e-05 4.895951874438887 0.5136394678821083 TIAATPIQTLPQSQST(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TIAATPIQTLPQSQSTPK 18 0 A0A0C4DG88;P14859-4;P14859-5;P14859-3;P14859;P14859-2;P14859-6 A0A0C4DG88 POU2F1 POU domain protein;POU domain, class 2, transcription factor 1 1 TIAATPIQTLPQSQS(0.205)T(0.795)PK 324.39 2.3853999999999995e-176 10158000.0 56182.0 54648.0 44995.0 52569.0 65534.0 49419.0 56976.0 55778.0 45922.0 41059.0 True False 65692.50295491968 60073.09228394991 46067.85144448774 49623.72936099752 52693.0831397553 46827.380642822594 51578.82080948166 54313.88660167612 46593.52237411135 48502.67167713486 1.3544099878087428 1.238552232417943 0.9498002862841276 1.0231133181966787 1.0863954771505069 0.9654598195030557 1.0634222616193936 1.1198122644299775 0.9606382651303821 1.0 15.565776597141891 -5.082597116740659 3.9964140581326366 1.0279149917346786 1.3354284861716854 0.8095489859121296 0.054533006712037736 0.08624046568028998 2.491354617429657 0.014064675898625117 0.04605244519709499 8.268045982140192e-06 5.082597116740659 0.3075134944370068 TIAPALVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TIAPALVSK 9 0 P06733;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8Y6I8 P06733 ENO1 Alpha-enolase;Enolase 0 ; 120.99 0.0075738 31080000.0 251040.0 270990.0 307740.0 338380.0 357240.0 338310.0 341760.0 290590.0 307150.0 270510.0 False True 293536.11373398965 297892.0962894812 315077.68871044845 319421.6656427621 287241.38646879804 320568.4280392826 309386.01867187035 282962.32040555595 311641.48767928843 319551.321644019 0.9185883263565082 0.9322198849214393 0.9860002677799775 0.9995942560944832 0.8988896837947855 1.0031829203210014 0.9681888251319054 0.8854988267605312 0.9752470622745785 1.0 18.285688128724168 -5.8695750307262955 0.004017186852980052 1.9016681780806899 1.829482957069531e-08 0.07967510540266676 0.04033017876136539 104872.0495906364 98.80594200539069 22938.825970219874 23836.751481379113 1.3502835264661156e-06 5.8695750307262955 -1.9016681597858602 TIAPALVSK ddPTM_PC-9_Lapatinib_30min_R1 2 TIAPALVSK 9 0 P06733;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8Y6I8 P06733 ENO1 Alpha-enolase;Enolase 0 ; 145.72 0.002199 112789000.0 866780.0 887160.0 914170.0 909600.0 931580.0 861000.0 900700.0 749440.0 843130.0 820590.0 False True 854419.5582520175 885105.8355269466 839010.4713982502 976495.018336651 876786.2959567482 824177.0370890296 947333.838841053 784261.7183652297 748167.8208474953 962427.8881325532 0.8877751453253192 0.9196593806569359 0.8717645048983608 1.014616295285658 0.9110150555362858 0.8563519898495682 0.9843166958505453 0.8148784215791708 0.7773754585387199 1.0 19.876318922320294 -7.778193403751326 24.998854027273136 0.8470952055460722 0.9196117201286407 0.10540547716029147 0.07061861138896035 428.35227025091274 639139.8332113771 0.0367217013894657 0.017717010013060735 1.6665049049904865e-08 7.778193403751326 0.07251651458256847 TIAQDYGVLK ddPTM_PC-9_AZD4547_30min_R2 2 TIAQDYGVLK 10 0 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 ; 146.11 0.00053605 14440100.0 75026.0 68856.0 79282.0 97358.0 81068.0 74676.0 71418.0 87277.0 63097.0 79187.0 False True 98882.70736225534 91112.35544753144 78230.6688780615 74913.61726610566 69813.1075355396 70006.49791499543 77774.06364500138 73790.3450759407 66432.17860492147 76414.68723264692 1.2940275088898006 1.1923408803616118 1.0237648246846285 0.9803562636856551 0.9136084967931807 0.9161392979579757 1.0177894651091852 0.9656565739945212 0.8693640059360135 1.0 16.22156233667495 -5.16488760490457 1.5050369650806499 0.9476578964938248 1.3262038257281243 0.891192839563921 0.040995699843859 0.1796191139194172 0.6089487232421908 0.01238620961538944 0.08166802195347296 6.840886660225261e-06 5.16488760490457 0.3785459292342995 TIAQDYGVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TIAQDYGVLK 10 0 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 ; 164.97 0.0038921 26059000.0 107312.0 105524.0 106741.0 120954.0 132101.0 115973.0 130309.0 100440.0 109979.0 114889.0 False True 125477.80209138744 115999.72533617925 109286.1102574968 114177.3395181589 106216.75734496296 109891.17172120172 117965.18816453879 97803.55642497663 111587.23481517368 135717.46623917622 0.9245516112882382 0.8547147876438527 0.8052472042537311 0.8412869963026207 0.7826314496453693 0.8097054474001116 0.8691968059339362 0.7206408956428384 0.822202461535219 1.0 17.050246875629156 -4.82648157765999 2.631483200734547 0.8206306415111582 0.9400920714940062 0.12821589825506297 0.06842679691071982 0.7117908386464702 7.041176595396291 0.016463536173300954 0.18255243075939043 1.4911400067873046e-05 4.82648157765999 0.11946142998284803 TIAQDYGVLK ddPTM_PC-9_Lapatinib_30min_R1 2 TIAQDYGVLK 10 0 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 ; 155.15 0.0012132 72202000.0 136744.0 138578.0 152877.0 125718.0 140955.0 125203.0 145076.0 120589.0 137057.0 121838.0 False True 134794.0054842219 138257.13115520723 140308.04318228533 134963.72110295418 132664.30402819248 119848.35955244795 152587.32541768017 126192.00517178829 121620.19738580691 142897.53596106955 0.943291321138978 0.9675263483400685 0.9818786743846326 0.944478994653366 0.9283876249926033 0.838701372605186 1.0678093529845782 0.8830943397524192 0.8511007314985519 1.0 17.124621514121806 -6.04099796663046 3.8110752790837026 0.9252030483733714 0.9646091716059884 0.057572693536073194 0.06440299829476717 0.6872189428141335 20.933076543404688 0.019280886249088577 0.026896006285057502 9.099175328619827e-07 6.04099796663046 0.03940612323261694 TICTFDSSGFES(ph)MSPIKETVSSR ddPTM_PC-9_AZD4547_30min_R2 1 TICTFDSSGFESMSPIKETVSSR 23 1 E9PEI0;Q69YH5 E9PEI0 CDCA2 Cell division cycle-associated protein 2 1 TICTFDS(0.009)S(0.009)GFES(0.527)MS(0.455)PIKET(0.001)VSSR 63.225 0.0041603000000000005 16310000.0 28429.0 24450.0 32883.0 47286.0 41039.0 36365.0 31045.0 37129.0 34636.0 37211.0 True False 37468.83064006556 32352.98435419056 32446.94993462947 36384.943261417386 35341.44323470423 34091.090801312544 33807.944857865994 31391.566189541303 36466.78824920457 35908.25421614691 1.0434601029202055 0.9009901778973803 0.9036070018697542 1.0132751941211366 0.9842150225953397 0.9493942700779577 0.9415090094428353 0.8742158836400745 1.0155544747370788 1.0 15.13202789345618 -4.74069700336982 24.818653656524123 0.9504531128964199 1.0434604736177298 0.24316915763168345 0.04723763167489672 2097.418466393805 2509460.2620367706 0.011784993502379203 0.5053815186448981 1.816782745569204e-05 4.74069700336982 0.09300736072130988 TICTFDSSGFES(ph)MSPIKETVSSR ddPTM_PC-9_Lapatinib_30min_R1 1 TICTFDSSGFESMSPIKETVSSR 23 1 E9PEI0;Q69YH5 E9PEI0 CDCA2 Cell division cycle-associated protein 2 1 TICTFDSS(0.001)GFES(0.544)MS(0.454)PIKETVSSR 84.946 5.3006999999999996e-05 9616700.0 35285.0 33987.0 36011.0 30799.0 32366.0 34392.0 24181.0 24272.0 34373.0 25489.0 True False 34781.82942952349 33908.305189655075 33050.31458647991 33064.06120245214 30462.295514004305 32921.134331667745 25432.973861458297 25399.76572929237 30501.550776263426 29894.73968804237 1.163476577902296 1.134256579702485 1.1055561925397779 1.1060160264809888 1.0189851402582693 1.10123502245567 0.850750805220467 0.849639969919258 1.020298256300381 1.0 14.867604028065726 -7.247695829697093 24.43453166590334 0.9176422590069823 1.1024268591757909 0.6556240105768631 0.06176297314344398 346.5744042820264 616172.2821430676 0.024214009106811256 0.018645952130632925 5.653327828352259e-08 7.247695829697093 0.1847846001688086 TICTFDSSGFESMS(ph)PIKETVSSR ddPTM_PC-9_AZD4547_30min_R2 2 TICTFDSSGFESMSPIKETVSSR 23 1 E9PEI0;Q69YH5 E9PEI0 CDCA2 Cell division cycle-associated protein 2 1 TICTFDS(0.001)S(0.001)GFES(0.168)MS(0.829)PIKET(0.001)VSSR;T(0.001)ICT(0.012)FDS(0.036)S(0.029)GFES(0.215)MS(0.663)PIKET(0.038)VS(0.003)S(0.003)R 83.723 7.0288e-05 25718000.0 44247.9 27984.8 49965.5 65399.0 70064.0 50379.0 52616.0 55484.0 51920.7 66251.0 True False 58317.81178650525 37030.33932740907 49302.92482312229 50322.270954477746 60336.82299267321 47228.79316593766 57298.72206930188 46910.22269548093 54665.12220379013 63931.572655234915 0.9121911031501898 0.5792183390686059 0.7711827314025133 0.7871270620206964 0.9437719187365031 0.738739736947022 0.8962507832913459 0.733756745645139 0.8550567416600846 1.0 15.964240962738982 -14.5228787451734 0.14003767051587923 1.694725477747099 0.7252125899586505 0.2731709353343924 0.10040934607994205 181.44139258853698 1.5509348875139861 35.19232300295176 0.6037720729613636 3.0000000007386935e-15 14.5228787451734 -0.9695128877884486 TICTFDSSGFESMS(ph)PIKETVSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TICTFDSSGFESMSPIKETVSSR 23 1 E9PEI0;Q69YH5 E9PEI0 CDCA2 Cell division cycle-associated protein 2 1 TICTFDS(0.001)S(0.001)GFES(0.136)MS(0.862)PIKETVSSR;TICTFDS(0.001)S(0.001)GFES(0.06)MS(0.937)PIKET(0.001)VSSR 97.488 1.2087e-05 36627000.0 121824.0 92296.0 122763.0 116603.0 144012.0 142807.0 137589.0 136240.0 125429.0 100816.0 True False 142446.39706632248 101458.53691698595 125690.13550127033 110070.11194202659 115793.88239879189 135317.94952264443 124555.57386190312 132663.84435821246 127263.1618366449 119093.14274098337 1.196092350809234 0.8519259344566037 1.055393556744361 0.9242355135544534 0.9722968067996403 1.13623628034528 1.0458668819648167 1.1139503190938886 1.0686019270935738 1.0 16.861730821153664 -6.744566778846585 24.996654550480585 1.078361472360627 0.9906326236013904 0.13383297917390213 0.09071920541008155 402.96651041379147 596991.3635571534 0.027896093549977217 0.027824607963189824 1.8006662355528876e-07 6.744566778846585 -0.08772884875923659 TICTFDSSGFESMS(ph)PIKETVSSR ddPTM_PC-9_Lapatinib_30min_R1 3 TICTFDSSGFESMSPIKETVSSR 23 1 E9PEI0;Q69YH5 E9PEI0 CDCA2 Cell division cycle-associated protein 2 1 TICTFDS(0.004)S(0.004)GFES(0.207)MS(0.784)PIKET(0.001)VSSR;TICTFDSSGFES(0.009)MS(0.99)PIKET(0.001)VSSR;TICTFDS(0.002)S(0.002)GFES(0.45)MS(0.534)PIKET(0.005)VS(0.005)S(0.001)R 97.839 3.6120999999999997e-06 32791400.0 127650.0 103789.0 120408.0 100143.0 105672.7 113640.9 102913.8 94557.5 106099.6 95911.1 True False 125829.68759185706 103548.6829472772 110508.51902832121 107507.85028725465 99457.23954652158 108780.74361687661 108242.17300290914 98950.98664912517 94149.54576968079 112489.20584149245 1.1185934388154768 0.9205210595333629 0.9823922055600409 0.9557170350970654 0.8841491839373984 0.9670327281904595 0.9622449744683257 0.8796487263725209 0.8369651564821791 1.0 16.779427045425066 TIDDLEDKLK ddPTM_PC-9_AZD4547_30min_R2 2 TIDDLEDKLK 10 1 A0A087WWU8;P06753-5;P06753-2;P06753-7;J3KN67 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 ; 130.98 0.00025268 18096400.0 125887.0 119403.0 143620.0 199776.0 175700.0 175894.0 149323.0 129147.0 146537.0 155934.0 False True 165916.4473877353 157997.68469707205 141715.50496035896 153720.72970843187 151307.08780276132 164895.32037415274 162612.45772301898 109190.29865282358 154282.64665878532 150474.79812261576 1.102619504779377 1.049994329072475 0.9417889688403556 1.02157126393465 1.005531090192707 1.0958334713284432 1.0806624082692753 0.7256384458735001 1.0253055567023701 1.0 17.199162355653897 TIDDLEDKLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TIDDLEDKLK 10 1 A0A087WWU8;P06753-5;P06753-2;P06753-7;J3KN67 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 94.40899999999999 0.008184100000000001 10447000.0 52260.0 48123.0 41169.0 67053.0 57831.0 65402.0 70965.0 69131.0 57648.0 45980.0 False True 61106.585817950574 52900.3334061726 42150.62509430197 63296.23779875906 46499.430693307106 61972.2039863591 64242.68145789229 67316.38450034922 58490.992940698874 54315.81002252024 1.1250239256786332 0.9739398783565822 0.7760286567911924 1.1653372705390084 0.8560938458623312 1.1409606882538323 1.1827620987564431 1.239351571346146 1.076868648676095 1.0 15.72908457244434 -6.844482932549207 10.641439688314627 1.1468422502975928 0.9781140549069515 0.26462329154091535 0.12194572553538717 0.5021346165930259 60.89959315510582 0.04167386352324085 0.03676248854779535 1.4305962010842245e-07 6.844482932549207 -0.16872819539064132 TIDDLEDKLK ddPTM_PC-9_Lapatinib_30min_R1 1 TIDDLEDKLK 10 1 A0A087WWU8;P06753-5;P06753-2;P06753-7;J3KN67 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 80.23100000000001 0.023253 9211300.0 49692.0 39240.0 45628.0 45366.0 43725.0 39171.0 44714.0 39103.0 40734.0 43064.0 False True 48983.38296760329 39149.142190898405 41876.64196917342 48702.366976539604 41153.181466657516 37495.74764206085 47029.07213271768 40919.86813251979 36146.10797196388 50507.55502082691 0.9698228898113337 0.7751145779033486 0.8291163955947874 0.9642590490958642 0.8147925879541764 0.7423789891749737 0.9311294540653399 0.8101732130103384 0.7156574488125379 1.0 15.624211584757424 TIDLGAAAHYTGDKAS(ph)PDQNASTHTPQSSVK ddPTM_PC-9_AZD4547_30min_R2 1 TIDLGAAAHYTGDKASPDQNASTHTPQSSVK 31 1 Q14677-2;Q14677;Q14677-3 Q14677-2 CLINT1 Clathrin interactor 1 1 TIDLGAAAHY(0.046)T(0.199)GDKAS(0.753)PDQNAS(0.002)THTPQSSVK 85.76 3.1056e-09 50747000.0 20929.0 16193.0 83532.0 136030.0 110140.0 91947.0 49884.0 112560.0 66306.0 90728.0 True False 27583.986649756687 21427.07057862607 82424.3111011608 104670.3851425497 94848.96215478754 86197.53955474436 54323.57936188713 95166.43837148257 69810.79979361816 87551.64033545373 0.31505962131684523 0.2447363692619389 0.9414365143285998 1.1955274023594027 1.0833487732654026 0.9845336903395397 0.6204747181634356 1.0869749328151108 0.7973671255745567 1.0 16.417846588267167 -5.268619132636392 10.94874413845041 0.967943334424581 0.27969420316220517 0.7620341075983581 0.15283566379762595 0.1323842703330827 198.54392858699853 0.04146376122347659 0.09271850172402213 5.387420411387817e-06 5.268619132636392 -0.6882491312623759 TIDLGAAAHYTGDKAS(ph)PDQNASTHTPQSSVK ddPTM_PC-9_Lapatinib_30min_R1 2 TIDLGAAAHYTGDKASPDQNASTHTPQSSVK 31 1 Q14677-2;Q14677;Q14677-3 Q14677-2 CLINT1 Clathrin interactor 1 1 TIDLGAAAHY(0.022)T(0.087)GDKAS(0.82)PDQNAS(0.035)T(0.035)HT(0.001)PQSSVK;TIDLGAAAHY(0.168)T(0.198)GDKAS(0.622)PDQNAS(0.007)T(0.004)HT(0.001)PQSSVK 76.267 5.8248e-07 40809000.0 68059.0 46822.0 150368.0 64467.0 121741.0 144727.0 68799.0 101055.0 171894.0 81158.0 True False 67088.46617950803 46713.58653573508 138005.32347726545 69208.11823560772 114580.43373201501 138537.3635851149 72361.07558390764 105750.38421941521 152533.4875959338 95186.0521637628 0.7048140421254756 0.4907608360032278 1.4498481693497935 0.7270825573954748 1.203752347401541 1.455437644863854 0.7602067103215298 1.1109861352110393 1.6024772971307566 1.0 16.538462567070113 -5.2486959076461295 24.9336146520451 1.1495299306396343 0.5977873762501313 0.3992507179589113 0.2772472991702474 743.5611762700421 1454829.949308676 0.06903549556893658 0.18004264428451994 5.64032452280713e-06 5.2486959076461295 -0.5517425543895029 TIEAAEALLHMES(ph)PTCLR ddPTM_PC-9_AZD4547_30min_R2 3 TIEAAEALLHMESPTCLR 18 0 Q15723-2;Q15723-3;Q15723-1;Q15723;Q15723-4;D6RHI1 Q15723-2 ELF2 ETS-related transcription factor Elf-2 1 TIEAAEALLHMES(0.723)PT(0.277)CLR;TIEAAEALLHMES(0.714)PT(0.286)CLR;TIEAAEALLHMES(0.905)PT(0.095)CLR 64.749 0.010839 7013600.0 29475.199999999997 28780.800000000003 41480.0 50139.0 45391.0 42793.0 33028.0 53715.0 38277.0 42238.0 True False 38847.70047775375 38083.63076078069 40929.94809744946 38580.22818982799 39089.24315569242 40117.14694515517 35967.42801628594 45414.580997904915 40300.24407595575 40759.26047624662 0.9531012099788495 0.9343552929026959 1.0041877016218759 0.9465389641284461 0.9590272909507904 0.9842461928016172 0.8824357359782514 1.114215038920328 0.9887383530778637 1.0 15.314840255466072 -7.760021156424222 24.999866876675682 1.038607507596086 0.9546166449980183 0.42994574042910294 0.04328602899549329 32.83975653157394 578923.6627957652 0.02022972407895568 0.010865422780666767 1.737716174770144e-08 7.760021156424222 -0.08399086259806776 TIEAAEALLHMES(ph)PTCLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TIEAAEALLHMESPTCLR 18 0 Q15723-2;Q15723-3;Q15723-1;Q15723;Q15723-4;D6RHI1 Q15723-2 ELF2 ETS-related transcription factor Elf-2 1 TIEAAEALLHMES(0.742)PT(0.258)CLR;TIEAAEALLHMES(0.827)PT(0.173)CLR;TIEAAEALLHMES(0.774)PT(0.226)CLR 107.73 0.0010221 2079800.0 27522.6 28243.8 34576.1 33897.2 45508.0 35092.0 44152.0 31490.9 36941.0 28538.4 True False 32181.632583871527 31047.657807228523 35400.52535458947 31998.049780205154 36591.03408191142 33251.71374406462 39969.60292720156 30664.297242366592 37481.192239494085 33712.18601014988 0.9545994013613491 0.9209624614043379 1.0500809809227818 0.949153809562256 1.0853948797890114 0.986341073641839 1.185612909087762 0.909590888978079 1.1117995204526177 1.0 15.040982559044538 -5.413708953845282 0.9555570807073582 1.043940430303008 0.9232793960126218 0.18127880237770222 0.07765136477610081 1.5336506513288788 2.080319763083452 0.027250401866863064 0.15640655496676284 3.857367758589857e-06 5.413708953845282 -0.12066103429038622 TIET(ph)SPSLSR ddPTM_PC-9_AZD4547_30min_R2 3 TIETSPSLSR 10 0 H3BP78;F8W7R3;Q9NVI1-2;Q9NVI1-1;Q9NVI1 H3BP78 FANCI Fanconi anemia group I protein 1 T(0.007)IET(0.497)S(0.497)PSLSR;T(0.166)IET(0.416)S(0.416)PS(0.003)LSR;T(0.021)IET(0.489)S(0.489)PS(0.001)LSR 150.09 0.00038930000000000003 94318300.0 306100.0 274322.0 428586.0 499489.0 447765.0 368736.0 310075.0 447327.0 292904.0 348629.0 True False 403433.4327244738 362991.2218409109 422902.6696068826 384339.5280781223 385600.5587365023 345678.8796291154 337671.0743051308 378202.8907018499 308386.30746463255 336423.60482440935 1.1991828960249062 1.078970728080653 1.2570540935366576 1.1424273522029522 1.1461756939967398 1.0275107771035765 1.0037080319657492 1.1241865471932224 0.9166607308235389 1.0 18.359919408830066 -6.72917847035778 3.622317924252474 1.0198231040893866 1.1668350900570201 0.5884686904545069 0.063024170445336 0.17150816493734572 4.719553731082403 0.021389987473511462 0.02037963010232791 1.8656128723896137e-07 6.72917847035778 0.14701198596763354 TIET(ph)SPSLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TIETSPSLSR 10 0 H3BP78;F8W7R3;Q9NVI1-2;Q9NVI1-1;Q9NVI1 H3BP78 FANCI Fanconi anemia group I protein 1 TIET(0.5)S(0.5)PSLSR;T(0.003)IET(0.494)S(0.494)PS(0.008)LSR;TIET(0.497)S(0.497)PS(0.007)LSR;T(0.001)IET(0.494)S(0.494)PS(0.011)LSR 144.17 0.00032298 85303000.0 282581.0 308714.0 308249.0 331932.0 369976.0 335325.0 325477.0 282470.0 299504.0 229266.0 True False 330416.3820708435 339361.0857002514 315598.8252008428 313334.92617806327 297481.85869493795 317739.9666940747 294645.46231058135 275055.46180170396 303883.6793940999 270830.11093134276 1.2200134650264431 1.2530404560011486 1.1653018348497048 1.1569427236157495 1.098407624144686 1.1732076821200428 1.0879346513478183 1.0156014811493113 1.1220453972015558 1.0 18.04702862131262 -1.5228787452803376 0.13918644300791463 0.9657633257020966 1.9702378846406965 0.7536154496789963 0.03841435025918176 35.19306314389036 0.32793237270465064 0.16602029765269352 7.021786691926795 0.029999999999999995 1.5228787452803376 1.0044745589386 TIET(ph)SPSLSR ddPTM_PC-9_Lapatinib_30min_R1 1 TIETSPSLSR 10 0 H3BP78;F8W7R3;Q9NVI1-2;Q9NVI1-1;Q9NVI1 H3BP78 FANCI Fanconi anemia group I protein 1 T(0.02)IET(0.486)S(0.486)PS(0.009)LSR 113.67 0.0031138999999999997 38645000.0 131910.0 93987.0 116620.0 85802.0 95692.0 95288.0 81970.0 86941.0 104530.0 58977.0 True False 130028.93921066856 93769.3788760442 107031.95376621836 92112.16530708136 90063.58469771044 91212.75436717701 86214.00551770975 90980.59625372464 92756.73065030159 69171.09586808727 1.8798160933960077 1.3556150542253527 1.5473508468093904 1.3316568741768073 1.3020407377883123 1.3186541751647867 1.2463877351621573 1.315297887245117 1.340975294466829 1.0 16.077881692570447 -1.5228787452803376 0.5510957053423908 1.2599276026503967 25.696530600014576 0.6859154682471671 0.11966585204872818 78.61770317316663 0.717587100512928 0.055258222975002554 2275.0060321587257 0.029999999999999995 1.5228787452803376 24.43660299736418 TIFPHTAGS(ph)NK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TIFPHTAGSNK 11 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 TIFPHT(0.005)AGS(0.995)NK 68.262 0.021338 7301100.0 85095.0 73154.0 82222.0 103240.0 128970.0 104740.0 106520.0 86073.0 96391.0 81840.0 True False 99499.9027971395 80416.24566205677 84182.48430867132 97455.79750859583 103699.25431889152 99247.2500157679 96429.65446198362 83813.67495188174 97800.53602114394 96676.9441549167 1.0291999159354814 0.8318037600898563 0.8707607076799609 1.0080562471278685 1.0726368652356466 1.0265865443236653 0.9974421027154435 0.8669458440636824 1.0116221284821207 1.0 16.560884251471492 -5.769086900755324 24.990934004675367 0.99639503292927 0.9027096882436368 0.2549109297637041 0.06775806296768955 226.80606548236042 741169.3956878297 0.019908950502931153 0.03018004428827556 1.7018179467065185e-06 5.769086900755324 -0.09368534468563317 TIFQGIAAK ddPTM_PC-9_Lapatinib_30min_R1 2 TIFQGIAAK 9 0 P52209-2;P52209;K7EMN2;K7EM49;K7EPF6 P52209-2 PGD 6-phosphogluconate dehydrogenase, decarboxylating 0 ; 120.12 0.0078156 26634000.0 56027.0 54750.0 53203.0 52557.0 54948.0 52137.0 57246.0 54975.0 53533.0 51316.0 False True 55228.04470590653 54623.22973882998 48828.854709519015 56422.2171050124 51716.06667192452 49907.2220472831 60209.91777317078 57529.33919610448 47503.54981251883 60185.902225728074 0.9176242718564387 0.9075751582814989 0.8113005355703684 0.9374656691761483 0.8592721012632275 0.8292178101792902 1.0003990228035902 0.9558607093790816 0.7892803473204755 1.0 15.877137973330212 -7.248628909004001 24.983738875178577 0.9327067510302738 0.877408190083309 0.1620405883005901 0.06585863711500602 1553.0662523692024 3028887.0624789987 0.025024860527141646 0.019265476431332033 5.641194723213336e-08 7.248628909004001 -0.055298560946964836 TIGGGDDS(ph)FNTFFSETGAGK ddPTM_PC-9_AZD4547_30min_R2 8 TIGGGDDSFNTFFSETGAGK 20 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;F8VRZ4;F8VS66;F8VWV9;F8VX09;F8VRK0;F8W0F6;F8VXZ7;P68363;P68363-2;Q71U36-2;Q71U36 Q9BQE3;P68363;Q71U36-2 TUBA1C;TUBA1B;TUBA1A;TUBA3E Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain;Tubulin alpha-1A chain 1 TIGGGDDS(0.997)FNT(0.003)FFSETGAGK;TIGGGDDS(0.994)FNT(0.005)FFSETGAGK;TIGGGDDS(0.991)FNT(0.001)FFS(0.008)ETGAGK;TIGGGDDS(1)FNTFFSETGAGK;TIGGGDDS(0.997)FNT(0.003)FFSETGAGK;TIGGGDDS(0.995)FNT(0.005)FFSETGAGK;TIGGGDDS(0.687)FNT(0.311)FFS(0.002)ETGAGK;TIGGGDDS(1)FNTFFSETGAGK 181.86 5.2845999999999995e-28 110899800.0 518404.1 483973.39999999997 654237.2 786919.1 684603.3 703411.4 615941.3 751355.5 571481.7 651410.2000000001 True False 683245.8203248645 640408.3369343315 645561.5872570074 605507.0592738993 589557.9489081402 659426.973960632 670758.8824635935 635250.7719067553 601689.0559589867 628604.5271718345 1.0869247528312715 1.0187777994784792 1.0269757205877352 0.9632559631699545 0.9378837145202097 1.0490331288695474 1.0670602158743852 1.0105730144274063 0.9571821868131565 1.0 19.26179313681343 -4.5520265753716815 1.658193393233862 1.0021004999941032 1.162560711382543 0.3094764415064146 0.038357238372796185 2.702109513262896 4.553750743041359 0.011643449232967338 0.8330479287111373 2.8052619729554744e-05 4.5520265753716815 0.1604602113884397 TIGGGDDS(ph)FNTFFSETGAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 12 TIGGGDDSFNTFFSETGAGK 20 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;F8VRZ4;F8VS66;F8VWV9;F8VX09;F8VRK0;F8W0F6;F8VXZ7;P68363;P68363-2;Q71U36-2;Q71U36 Q9BQE3;P68363;Q71U36-2 TUBA1C;TUBA1B;TUBA1A;TUBA3E Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain;Tubulin alpha-1A chain 1 T(0.007)IGGGDDS(0.66)FNT(0.324)FFS(0.009)ETGAGK;TIGGGDDS(1)FNTFFSETGAGK;TIGGGDDS(0.797)FNT(0.201)FFS(0.001)ETGAGK;TIGGGDDS(0.993)FNT(0.006)FFSETGAGK;T(0.001)IGGGDDS(0.876)FNT(0.119)FFS(0.003)ET(0.001)GAGK;TIGGGDDS(0.994)FNT(0.006)FFSETGAGK;TIGGGDDS(0.859)FNT(0.141)FFSETGAGK;TIGGGDDS(0.999)FNT(0.001)FFSETGAGK;TIGGGDDS(0.998)FNT(0.001)FFS(0.001)ETGAGK;TIGGGDDS(0.996)FNT(0.003)FFSETGAGK;T(0.001)IGGGDDS(0.981)FNT(0.018)FFSET(0.001)GAGK;T(0.03)IGGGDDS(0.91)FNT(0.059)FFSETGAGK 205.24 4.5894e-21 94355300.0 529629.6 541851.9 526303.0 629327.2999999999 656971.5 601241.6 650114.4 588764.9 567778.8999999999 464156.3 True False 619285.4306185778 595643.3756575458 538852.0595352437 594068.1316876352 528242.6506843731 569711.4320706541 588530.8576113397 573310.445222977 576081.5922803527 548304.1629307518 1.129456007243174 1.0863375037566014 0.9827612043924936 1.0834645655657063 0.9634117090427555 1.039042689418001 1.0733656561452523 1.045606588428152 1.0506606209245744 1.0 19.06461690159469 -5.02730977191536 5.657418865221119 1.0327334015762628 1.120687388011042 0.44321438542559044 0.036362258505688236 0.1389262971365933 14.294663108476405 0.009015609702944086 0.028108219075840275 9.390532672891283e-06 5.02730977191536 0.08795398643477914 TIGGGDDS(ph)FNTFFSETGAGK ddPTM_PC-9_Lapatinib_30min_R1 6 TIGGGDDSFNTFFSETGAGK 20 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;F8VRZ4;F8VS66;F8VWV9;F8VX09;F8VRK0;F8W0F6;F8VXZ7;P68363;P68363-2;Q71U36-2;Q71U36 Q9BQE3;P68363;Q71U36-2 TUBA1C;TUBA1B;TUBA1A;TUBA3E Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain;Tubulin alpha-1A chain 1 TIGGGDDS(0.994)FNT(0.002)FFS(0.003)ET(0.001)GAGK;TIGGGDDS(0.985)FNT(0.015)FFSETGAGK;TIGGGDDS(0.96)FNT(0.04)FFSETGAGK;T(0.003)IGGGDDS(0.992)FNT(0.005)FFSETGAGK;T(0.001)IGGGDDS(0.986)FNT(0.014)FFSETGAGK;T(0.001)IGGGDDS(0.997)FNT(0.002)FFSETGAGK 203.26 2.4865999999999998e-21 88163700.0 619208.6 576782.0 639656.7 562003.7 594193.6 613708.9 524270.3 523786.2 607257.6 421177.30000000005 True False 610378.5718150489 575446.4967163804 587066.5952722671 603335.3268873856 559244.3006775645 587462.0009723208 551414.4508597212 548123.2190275325 538861.8543819817 493977.2351215239 1.2356410952113794 1.1649251337965283 1.1884486845387565 1.2213828573273389 1.13212565461642 1.1892491378227148 1.116275025759167 1.1096123061069567 1.0908637404098502 1.0 18.914085031360024 -8.210870448107288 0.3776857431160047 0.988419419556376 1.2130445227161593 0.8512686559313996 0.025724107929337568 0.4308640071466026 0.18439692572984542 0.03632701385041397 0.024824935259460473 6.15360409963372e-09 8.210870448107288 0.22462510315978323 TIGGGDDS(ph)FTTFFCETGAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TIGGGDDSFTTFFCETGAGK 20 0 P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8;C9JDL2 P68366-2 TUBA4A Tubulin alpha-4A chain 1 T(0.225)IGGGDDS(0.397)FT(0.188)T(0.188)FFCET(0.001)GAGK 46.839 0.041557 1332900.0 7624.1 8092.1 7933.0 7741.2 7719.3 8448.2 8286.5 8265.1 8319.0 6863.4 True False 8914.709547161061 8895.430209174188 8122.152806070034 7307.485661309018 6206.758578458704 8005.16151979388 7501.542730935307 8048.149882597323 8440.649636998223 8107.680089355495 1.0995388876856536 1.0971609771398017 1.0017850626264275 0.9013041438207404 0.7655406367855467 0.9873553755905823 0.9252391125772241 0.992657553566238 1.0410684121688374 1.0 12.985073449119863 -5.4206120747627 3.2058651239338585 0.9383416528395484 1.0991202838517549 0.415213656461198 0.07173871637262857 0.2490308237143135 4.794212080962681 0.02105690208416682 0.04917693965156659 3.7965395219263827e-06 5.4206120747627 0.16077863101220646 TIGGGDDSFNTFFS(ph)ETGAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TIGGGDDSFNTFFSETGAGK 20 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;F8VRZ4;F8VS66;F8VWV9;F8VX09;F8VRK0;F8W0F6;F8VXZ7;P68363;P68363-2;Q71U36-2;Q71U36 Q9BQE3;P68363;Q71U36-2 TUBA1C;TUBA1B;TUBA1A;TUBA3E Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain;Tubulin alpha-1A chain 1 TIGGGDDSFNT(0.03)FFS(0.966)ET(0.004)GAGK 175.56 5.8957e-37 0.0 7775.4 10525.0 9271.5 10359.0 11492.0 12099.0 11252.0 10227.0 9061.8 9329.5 True False 9091.621648849852 11569.852442698228 9492.56772235956 9778.618814331128 9240.225096012266 11464.507140927786 10186.129102574556 9958.552086402206 9194.311681758682 11020.864497718634 0.8249463234696204 1.0498135101010666 0.8613269607229598 0.8872823739331288 0.8384301520016902 1.0402547951933343 0.9242586282304014 0.9036089762707515 0.8342641072904892 1.0 13.427949775659393 TIGGGDDSFNTFFS(ph)ETGAGK ddPTM_PC-9_Lapatinib_30min_R1 1 TIGGGDDSFNTFFSETGAGK 20 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;F8VRZ4;F8VS66;F8VWV9;F8VX09;F8VRK0;F8W0F6;F8VXZ7;P68363;P68363-2;Q71U36-2;Q71U36 Q9BQE3;P68363;Q71U36-2 TUBA1C;TUBA1B;TUBA1A;TUBA3E Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain;Tubulin alpha-1A chain 1 TIGGGDDS(0.002)FNT(0.176)FFS(0.82)ET(0.003)GAGK 132.79 4.5648e-05 3056800.0 38538.0 32788.0 38535.0 31986.0 32987.0 33784.0 28510.0 33477.0 33516.0 24574.0 True False 37988.44105299635 32712.08140048872 35366.801049401634 34338.35714216804 31046.769514937263 32339.13707435051 29986.108299498643 35032.463633796986 29741.075140873523 28821.583157203262 1.318055321451072 1.1349855843124677 1.2270943222132664 1.1914112057923505 1.0772055561832616 1.1220458257952468 1.0404046209378452 1.215494077570873 1.031902896473626 1.0 14.814861963858606 -1.5228787452803438 0.1682541117983474 1.0089510338833614 2.032786758474342 0.5647349208927024 0.06360824326156797 48.68798641586928 0.5231021478730217 0.16564743691369194 12.510385814449883 0.029999999999999565 1.5228787452803438 1.0238357245909808 TIGGGDDSFNTFFSETGAGK ddPTM_PC-9_AZD4547_30min_R2 2 TIGGGDDSFNTFFSETGAGK 20 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;F8VRZ4;F8VS66;F8VWV9;F8VX09;F8VRK0;F8W0F6;F8VXZ7;P68363;P68363-2;Q71U36-2;Q71U36 Q9BQE3;P68363;Q71U36-2 TUBA1C;TUBA1B;TUBA1A;TUBA3E Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain;Tubulin alpha-1A chain 0 ; 203.2 2.6777000000000003e-20 19103000.0 67026.0 74098.0 87379.0 117179.0 110318.0 98484.0 84684.0 105221.0 80055.0 96365.0 False True 88338.87377259276 98048.72943463452 86220.29736757568 90165.19194750307 95002.24992729141 92325.77991135619 92220.71194535405 88961.51218803968 84286.54386447837 92991.29068122337 0.9499693264331687 1.0543861550513174 0.9271868014300518 0.9696089954982102 1.021625242873138 0.9928433000016252 0.9917134311157065 0.9566649901978683 0.9063918055876318 1.0 16.504807983088533 -7.844338441535226 4.922310599540452 0.9468221877848634 0.9879701837176448 0.1188758635592917 0.03942708318392981 0.37069393733438183 15.58292930440591 0.02160336617391849 0.010118583339157286 1.4310722437104631e-08 7.844338441535226 0.0411479959327814 TIGGGDDSFNTFFSETGAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TIGGGDDSFNTFFSETGAGK 20 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;F8VRZ4;F8VS66;F8VWV9;F8VX09;F8VRK0;F8W0F6;F8VXZ7;P68363;P68363-2;Q71U36-2;Q71U36 Q9BQE3;P68363;Q71U36-2 TUBA1C;TUBA1B;TUBA1A;TUBA3E Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain;Tubulin alpha-1A chain 0 ; 171.11 7.162399999999999e-08 14190000.0 60565.0 61384.0 63545.0 65770.0 91601.0 70396.0 67706.0 79073.0 63581.0 52991.1 False True 70817.4582867236 67477.79784727666 65060.15379575452 62085.12012921696 73652.44161328042 66704.3098349246 61292.397531008966 76997.41753476902 64510.75184156559 62597.966952683244 1.1313060428983794 1.0779551019329747 1.0393333356166727 0.9918072926577002 1.176594787318781 1.065598662099446 0.9791435810900834 1.2300306428956402 1.030556661533883 1.0 15.933828181836558 -4.77521950406461 4.635807572824873 1.070102591475664 1.1353027260193194 0.06005009733395317 0.07666410560164917 0.6187687834377994 30.49847719553696 0.01868025518323648 0.1305091901820929 1.6779557199959956e-05 4.77521950406461 0.06520013454365547 TIGGGDDSFNTFFSETGAGK ddPTM_PC-9_Lapatinib_30min_R1 2 TIGGGDDSFNTFFSETGAGK 20 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;F8VRZ4;F8VS66;F8VWV9;F8VX09;F8VRK0;F8W0F6;F8VXZ7;P68363;P68363-2;Q71U36-2;Q71U36 Q9BQE3;P68363;Q71U36-2 TUBA1C;TUBA1B;TUBA1A;TUBA3E Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain;Tubulin alpha-1A chain 0 ; 357.92 1.6695999999999992e-248 98881000.0 156485.0 146636.0 163913.0 144034.0 146940.0 140657.0 148354.0 130169.0 135740.0 139586.0 False True 154253.49520416543 146296.47335128897 150436.70586247725 154626.74084333854 138297.27809515514 134641.42799748163 156035.04421830302 136217.12694529723 120451.53179443162 163713.25411334625 0.9422175134175063 0.8936141068334098 0.9189036445291288 0.9444973877086538 0.8447530949412657 0.8224222817308557 0.9530996440292656 0.832047030541509 0.7357469769126784 1.0 17.320811600583255 -6.266223471378045 24.430294560754742 0.8585888004501387 0.9221582654706494 0.14947383854253182 0.06924609959412051 555.6867786190805 2837646.6569968984 0.020918456926173844 0.024501778436345472 5.417220691548212e-07 6.266223471378045 0.06356946502051064 TIGGGDDSFTTFFCETGAGK ddPTM_PC-9_Lapatinib_30min_R1 1 TIGGGDDSFTTFFCETGAGK 20 0 P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8;C9JDL2 P68366-2 TUBA4A Tubulin alpha-4A chain 0 330.9 7.417199999999999e-178 4416000.0 21564.0 15179.0 18525.0 17316.0 19924.0 20401.0 21595.0 15594.0 18737.0 20524.0 False True 21256.493405646717 15143.853958094984 17001.946008567946 18589.476404482644 18752.109492091135 19528.496787053784 22713.083434853495 16318.554168695828 16626.64175064289 24071.54605348904 0.8830547634295265 0.6291184589657864 0.7063088499088577 0.7722593456679199 0.7790155833955301 0.8112689041102632 0.9435656265859731 0.67791882301347 0.6907176511927015 1.0 14.55504118492941 -6.20254075924118 2.168567208732652 0.809665211684728 0.730622152608 0.08913970545338834 0.10987139644825741 0.8482052894889677 7.8297214511957005 0.036728346230220935 0.04934664835808981 6.272768222747089e-07 6.20254075924118 -0.07904305907672804 TIIFVETK ddPTM_PC-9_Lapatinib_30min_R1 1 TIIFVETK 8 0 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 121.96 0.015433 3141400.0 25225.0 21434.0 26090.0 21669.0 26089.0 24602.0 18402.0 23614.0 23581.0 23952.0 False True 24865.28687430153 21384.370889901034 23944.98091031243 23262.61054566495 24554.496312947467 23549.829810063082 19354.765518322474 24711.19264714528 20925.05946106152 28092.071285966143 0.8851354042634583 0.7612244277830787 0.8523750586619984 0.8280845619698456 0.8740721203143917 0.8383087729749492 0.6889760929800668 0.8796500761939245 0.7448742119458801 1.0 14.77787538079641 TIIPLISQCTPK ddPTM_PC-9_Lapatinib_30min_R1 1 TIIPLISQCTPK 12 0 P40926;G3XAL0;P40926-2 P40926 MDH2 Malate dehydrogenase, mitochondrial;Malate dehydrogenase 0 109.24 0.006157999999999999 2187900.0 42157.0 41490.0 50621.0 44128.0 44414.0 41036.0 32884.0 30644.0 48922.0 34979.0 False True 41555.83344935304 41393.932454138 46459.13678271078 47373.320326692694 41801.655841283646 39280.98593958818 34586.572617352256 32067.832111422027 43411.88918850142 41025.07354341227 1.0129374516630452 1.0089910603166965 1.13245712365508 1.1547406557739082 1.0189294553500217 0.9574872766046716 0.8430593690649485 0.7816642199919084 1.0581794361090773 1.0 15.324218299531486 -6.755885384414974 2.7580436239669504 0.9034882065671492 1.076379218856367 0.4041183258754635 0.0843810738735471 0.24747303539004756 3.862822652846013 0.03203836916353993 0.029829968277724633 1.7543434332778582e-07 6.755885384414974 0.17289101228921777 TILETS(ph)FHQHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TILETSFHQHR 11 0 Q5M775;Q5M775-4;Q5M775-2;Q5M775-5;Q5M775-3 Q5M775 SPECC1 Cytospin-B 1 TILET(0.081)S(0.918)FHQHR 57.52 0.04306 5156000.0 13837.0 12652.0 19754.0 20012.0 20935.0 17124.0 19275.0 17729.0 13432.0 15085.0 True False 16179.330806792617 13908.006945844945 20225.01027746218 18890.792519779392 16832.93703315495 16225.987294920847 17449.132461084653 17263.632535428234 13628.41758915256 17819.7910872057 0.9079416659608931 0.7804809202185682 1.1349746009078292 1.0601017950958276 0.9446203353775964 0.9105599058661705 0.9791996087772784 0.9687898388339257 0.7647910978562216 1.0 14.121192802872862 TILETS(ph)FHQHR ddPTM_PC-9_Lapatinib_30min_R1 1 TILETSFHQHR 11 0 Q5M775;Q5M775-4;Q5M775-2;Q5M775-5;Q5M775-3 Q5M775 SPECC1 Cytospin-B 1 TILET(0.056)S(0.944)FHQHR 112.02 0.00098567 6964900.0 23983.0 20811.0 23197.0 19427.0 18418.0 20552.0 17506.0 16588.0 24387.0 15617.0 True False 23640.998022056443 20762.813408124017 21289.832203009482 20855.7263865722 17334.68945118121 19673.038869051965 18412.375022484157 17358.73903747124 21640.279253505272 18316.377641655534 1.2907026970382798 1.133565479721533 1.1623385704055178 1.1386381518549618 0.9464038026688342 1.074068205730323 1.005241068005188 0.9477168126296759 1.1814715593267986 1.0 14.160846595039738 -5.004671603140606 0.708389864219695 1.02381883129277 1.3635863069146001 0.5316170857918527 0.07323494630873915 1.8358250119722963 0.8581036348345832 0.03183118383670258 0.4758092175825767 9.893008833473702e-06 5.004671603140606 0.3397674756218301 TILSNQTVDIPENVDITLK ddPTM_PC-9_Lapatinib_30min_R1 1 TILSNQTVDIPENVDITLK 19 0 D6RAN4;P32969;E7ESE0 D6RAN4 RPL9 60S ribosomal protein L9 0 233.4 9.007299999999998e-43 2633800.0 9202.4 8722.7 8016.3 5758.0 6643.9 6717.0 6783.8 5409.2 7005.6 5938.6 False True 9071.172088486524 8702.503124071096 7357.230757812853 6181.462528124922 6253.118864409968 6429.729568091771 7135.031970611676 5660.531179255449 6216.555555761528 6965.079097312901 1.3023789050703165 1.249447852994015 1.056302542300093 0.8874935146838039 0.897781457617961 0.9231380546090762 1.024400709729821 0.8127016362871256 0.8925319395381813 1.0 12.765924021214834 -5.382086954232718 2.2429918633983283 0.9152449492311102 1.2971300560960217 0.8594021769457771 0.05721774213725341 0.1078245598466577 1.0294146400646842 0.016334879202430402 0.04805303463658808 4.148709690518665e-06 5.382086954232718 0.3818851068649115 TIMQLCHDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TIMQLCHDR 9 0 A0A087WVZ9;A0A0A0MQR7;P19388 A0A087WVZ9 POLR2E DNA-directed RNA polymerases I, II, and III subunit RPABC1 0 64.84100000000001 0.044269 336750.0 1998.0 914.15 655.32 1002.9 2470.9 1274.1 1024.0 866.9 717.75 739.44 False True 2336.2219377012098 1004.9007705931198 670.94531411494 946.7107644456697 1986.7448825040635 1207.2839530751385 926.9993068820073 844.1447935564747 728.2457359004056 873.4946185961811 2.674569353908351 1.1504372771158284 0.7681161392765486 1.0838198018519638 2.274478674747899 1.382130956931824 1.0612535980723214 0.9663995353664853 0.8337151945718805 1.0 9.770655004824581 -4.760499391431199 24.976552279575163 1.1905390446441784 2.6745711153835416 0.5548278322814654 0.40418468550960496 19.3991524638084 515182.5948496092 0.10952701889390029 0.6467248833950813 1.7358036952192644e-05 4.760499391431199 1.4840320707393633 TIMQVSS(ph)GSRGSSGEAT(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 TIMQVSSGSRGSSGEATR 18 1 K7EJ87 K7EJ87 POLR2E 2 T(0.336)IMQVS(0.283)S(0.347)GS(0.034)RGSS(0.045)GEAT(0.955)R;T(0.093)IMQVS(0.375)S(0.463)GS(0.068)RGSS(0.002)GEAT(0.998)R 86.76100000000001 0.006246 50498500.0 10996.0 6648.6 14170.5 17268.2 15748.300000000001 13609.5 12748.7 11135.0 5911.5 15733.900000000001 True False 14492.499268991569 8797.629929540746 13982.589911159777 13287.283281030479 13561.920380445266 12758.495813569722 13883.309602495598 9414.341606844859 6223.969821433558 15183.060950026444 0.9545176243902471 0.5794371739991878 0.9209335296210758 0.8751386380364453 0.8932270261631036 0.8403111767490797 0.914394643358882 0.6200555762656319 0.4099285277138216 1.0 13.890175051215381 -7.769882795405628 24.987790133409256 0.6362439572659774 0.8478048856966662 0.17864698175334748 0.16728912675297242 261.3650489500395 773480.2459755538 0.08506719638234983 0.041906760040961874 1.698702025356686e-08 7.769882795405628 0.21156092843068885 TIMQVSS(ph)GSRGSSGEAT(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 TIMQVSSGSRGSSGEATR 18 1 K7EJ87 K7EJ87 POLR2E 2 T(0.345)IMQVS(0.291)S(0.356)GS(0.008)RGSS(0.032)GEAT(0.968)R 86.76100000000001 0.006246 18288000.0 15743.0 6085.8 9883.9 11587.0 2964.9 15448.0 5391.1 12642.0 4224.6 10823.0 True False 15518.501933087373 6071.70870401044 9071.28389495733 12439.146633098895 2790.510411217678 14787.325051046848 5670.224779145107 13229.393471889996 3748.781060989801 12693.741129259002 1.2225317796435373 0.47832302882049366 0.7146265078659965 0.979943304848618 0.2198335685911829 1.1649304094410864 0.44669453405468235 1.042198146092354 0.29532515456368347 1.0 13.631829705875623 -4.744719763311685 24.592856273765474 0.7060578460105937 1.222533633649619 0.19298810043921166 0.3176934021283388 1295.9692256589385 1906112.5434607083 0.07123131833985022 1.914007727934525 1.800032045023539e-05 4.744719763311685 0.5164757876390254 TIMQVSSGS(ph)RGSSGEAT(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 TIMQVSSGSRGSSGEATR 18 1 K7EJ87 K7EJ87 POLR2E 2 T(0.085)IMQVS(0.174)S(0.216)GS(0.525)RGS(0.001)S(0.449)GEAT(0.55)R 81.37899999999999 0.011503 19643000.0 18256.0 11862.0 10644.0 15406.0 14554.0 10272.0 5859.8 11388.0 11376.0 5036.8 True False 17995.666092259613 11834.534267799103 9768.891407028184 16539.008632909423 13697.96233426492 9832.690505201523 6163.191771778395 11917.128053937942 10094.715085409274 5907.404168885865 3.0462899740366995 2.003339187477855 1.653669044430829 2.7997083253622503 2.3187785942278523 1.6644688976911437 1.0432994925655767 2.0173205884075323 1.7088241800989106 1.0 12.528308605358117 -6.807978012309507 4.608873493730097 1.5081023973682612 2.331996308873138 0.4827709606227142 0.45561316841819943 0.20548956258816234 9.379364049970977 0.1649572174610131 0.14874141179628086 1.556044409849377e-07 6.807978012309507 0.8238939115048767 TIPIDGNFFTYTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TIPIDGNFFTYTR 13 0 P00352;Q5SYQ7;Q5SYQ9;Q5SYQ8 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ; 170.4 0.00044484 11523200.0 12807.2 13762.8 9715.4 14767.2 13610.3 14237.8 18957.9 14860.7 13811.5 14298.5 False True 14975.20600626974 15129.079828823476 9947.05198185968 13939.841659908365 10943.459417356049 13491.144703785574 17162.070468689857 14470.622371213185 14013.467058709099 16890.704863136285 0.8865944984304892 0.8957044689024477 0.5889068610492967 0.8252966215952221 0.6478983266849916 0.7987318950335696 1.016065972838459 0.8567210479649731 0.8296555515153949 1.0 14.043941913806737 -7.022716160833423 22.99996434225763 0.9127748357353636 0.7644870395050949 0.33728228858892306 0.10419957217684508 351.0970981090463 355482.10424267047 0.04006763386414439 0.031331727080111296 9.490385179083505e-08 7.022716160833423 -0.14828779623026866 TIPIDGNFFTYTR ddPTM_PC-9_Lapatinib_30min_R1 1 TIPIDGNFFTYTR 13 0 P00352;Q5SYQ7;Q5SYQ9;Q5SYQ8 P00352 ALDH1A1 Retinal dehydrogenase 1 0 147.26 0.00050076 115580000.0 28277.0 30512.0 24782.0 32962.0 30682.0 21737.0 32134.0 23508.0 19313.0 31111.0 False True 27873.764794633305 30441.351338651675 22744.51962128641 35386.135438008605 28877.345083132896 20807.359181421878 33797.74128713044 24600.26750017326 17137.76656509399 36488.49489719825 0.7639055782696473 0.8342725953596156 0.6233340039200366 0.9697888481754205 0.7914095981347322 0.5702443808670102 0.9262574787573817 0.6741924425625508 0.4696758968375509 1.0 15.155154022411244 -6.5616186061079524 24.99601864684034 0.7157341301402274 0.7995446793961093 0.03892674793032558 0.1646433269392313 527.4178195236005 340301.07158607634 0.0528432825589888 0.05284336021579351 2.743982857621885e-07 6.5616186061079524 0.08381054925588194 TIPSLTSTS(ph)TPLR ddPTM_PC-9_AZD4547_30min_R2 2 TIPSLTSTSTPLR 13 0 Q86T82-2;Q86W68;Q86T82 Q86T82-2;Q86T82 USP37 Ubiquitin carboxyl-terminal hydrolase 37 1 TIPS(0.007)LT(0.028)S(0.117)T(0.117)S(0.365)T(0.365)PLR;TIPSLT(0.002)S(0.012)T(0.064)S(0.558)T(0.363)PLR 112.84 0.00041037 8320000.0 47661.0 38937.0 49877.0 69833.0 65634.0 56501.0 47450.0 56147.0 44140.0 58711.0 True False 62816.206589614994 51522.62379546497 49215.59839094711 53734.08075909482 56521.852025307155 52967.9835381537 51672.958077169926 47470.77127970525 46473.15028640399 56655.54576023756 1.1087388841941253 0.9094012440283469 0.8686810396148013 0.948434615500728 0.9976402356885558 0.9349125990650698 0.9120547226893972 0.8378839289731379 0.8202753969236342 1.0 15.789929561529865 -7.375693310844307 2.746980441931918 0.8726587631936973 0.9566581314782082 0.16568969383869514 0.07458304541457902 0.47360810745087345 6.920644138647524 0.0361731720788176 0.022414487412392662 4.2102384115231876e-08 7.375693310844307 0.08399936828451093 TIPSLTSTST(ph)PLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TIPSLTSTSTPLR 13 0 Q86T82-2;Q86W68;Q86T82 Q86T82-2;Q86T82 USP37 Ubiquitin carboxyl-terminal hydrolase 37 1 TIPS(0.016)LT(0.009)S(0.003)T(0.012)S(0.084)T(0.875)PLR 87.831 0.016881 3983500.0 16337.0 15165.0 15215.0 14142.0 18572.0 15555.0 15704.0 16765.0 15665.0 12396.0 True False 19102.531429541898 16670.480978006515 15577.783303208833 13349.669588982613 14932.949920217514 14739.26841698749 14216.403432885785 16324.936513985815 15894.070989731596 14643.296673317995 1.3045239644942257 1.1384376995094496 1.0638166835473324 0.9116573874588951 1.0197806036005066 1.0065539711316762 0.9708471903591174 1.114840249308886 1.085416169891079 1.0 13.837952766425014 -4.875307844941668 1.8307914468335966 1.018075305677596 1.362349316147239 0.7281341377098991 0.0540896161648302 0.37998004157184573 1.5527844696315405 0.016058010572336134 0.21421885833062906 1.3325765148700816e-05 4.875307844941668 0.3442740104696431 TIPSLTSTST(ph)PLR ddPTM_PC-9_Lapatinib_30min_R1 2 TIPSLTSTSTPLR 13 0 Q86T82-2;Q86W68;Q86T82 Q86T82-2;Q86T82 USP37 Ubiquitin carboxyl-terminal hydrolase 37 1 TIPSLTST(0.002)S(0.017)T(0.98)PLR;TIPSLT(0.003)S(0.012)T(0.012)S(0.057)T(0.916)PLR 111.72 0.0013081 7629000.0 46584.0 41221.0 48476.0 46069.0 43557.0 42766.0 33166.0 37832.0 46773.0 28664.0 True False 45919.70361754066 41125.55530711067 44490.49040277138 49457.067941678884 40995.062896356845 40936.99787241514 34883.17319751569 39589.81283250614 41504.932198474664 33618.5342076208 1.365904394699379 1.2233000717142553 1.3233917376649358 1.471125053705278 1.2194185101343262 1.2176913371534013 1.0376173149633694 1.1776186489276423 1.2345848258032064 1.0 15.036969202948729 -6.698487668744749 2.389764955518381 1.1310777813068038 1.3346177308767875 0.5572761909465975 0.08882978856557386 0.23961554395274454 2.800832404331722 0.03352166951969282 0.03221822772547584 2.0022224714153119e-07 6.698487668744749 0.20353994956998367 TIPSWATLS(ph)ASQLAR ddPTM_PC-9_AZD4547_30min_R2 1 TIPSWATLSASQLAR 15 0 Q5SSJ5;B0QZK4;Q5SWC8;Q5SSJ5-2 Q5SSJ5 HP1BP3 Heterochromatin protein 1-binding protein 3 1 TIPSWAT(0.013)LS(0.776)AS(0.211)QLAR 88.311 0.0048883 2271500.0 7625.9 8033.5 10788.0 12368.0 11889.0 12057.0 10514.0 12526.0 9882.5 10859.0 True False 10050.77757142622 10630.171771345187 10644.944071246022 9516.748683695181 10238.417569078169 11303.07388399354 11449.725631683134 10590.394518844967 10404.868774476387 10478.82971522236 0.9591507682223027 1.0144426486769773 1.0158523767002674 0.908188122369277 0.9770573477499161 1.0786580363620013 1.0926530865417514 1.0106466854271463 0.9929418701557358 1.0 13.355189983989641 -6.732131040110505 22.543744672294494 1.0392498838344832 0.9756974649013781 0.3460355554673946 0.04105459081976608 84.37752770190444 64901.59043720081 0.014495371072944492 0.01449127829781963 1.852972439820974e-07 6.732131040110505 -0.06355241893310515 TIPSWATLSAS(ph)QLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TIPSWATLSASQLAR 15 0 Q5SSJ5;B0QZK4;Q5SWC8;Q5SSJ5-2 Q5SSJ5 HP1BP3 Heterochromatin protein 1-binding protein 3 1 TIPSWAT(0.003)LS(0.189)AS(0.808)QLAR 88.78 0.021567 0.0 8026.0 7367.7 6761.1 11522.0 11958.0 9766.8 9007.9 8344.9 11084.0 5947.6 True False 9384.64327927423 8099.11656456701 6922.3102656145375 10876.459694828005 9614.915741221246 9254.611814531245 8154.606500451597 8125.8552171524125 11246.082531132142 7025.852798824308 1.3357301309877483 1.1527592160658846 0.9852626384049639 1.54806256354361 1.3685051504110914 1.3172225606662145 1.1606571805512595 1.1565649679583634 1.6006715274498833 1.0 12.778457635114934 -11.66745169145114 2.634426711684142 0.32374229509389 1.281333589947771 0.19148424075629 0.178685850743997 36530570.692731366 30733360.70043065 143035483.61301157 0.04585310351584747 2.1505438808052206e-12 11.66745169145114 0.957591294853881 TIPWLEDR ddPTM_PC-9_AZD4547_30min_R2 1 TIPWLEDR 8 0 O43707;O43707-2;K7EJH8 O43707 ACTN4 Alpha-actinin-4 0 101.64 0.020839 8380500.0 24969.0 33423.0 38031.0 29023.0 28423.0 39179.0 28295.0 40851.0 32987.0 31557.0 False True 32908.62261253641 44226.33112761192 37526.684090986026 22332.195750880106 24476.957066692645 36729.130936467016 30813.200185321864 34538.41661259266 34730.62547570477 30452.19903520325 1.0806648995855272 1.4523197840814563 1.2323144232573993 0.7333524821988624 0.8037829070536703 1.206124092844905 1.0118546824714132 1.1341846469828227 1.1404964690909707 1.0 14.894258792332321 -5.548016842069114 24.87239372103306 1.0081152666397244 1.2854486677192154 0.3371200220372773 0.16116273437703213 222.89946144572033 220542.35310735588 0.04580243752779491 0.07933589980766281 2.8312821957051306e-06 5.548016842069114 0.277333401079491 TIPWLEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TIPWLEDR 8 0 O43707;O43707-2;K7EJH8 O43707 ACTN4 Alpha-actinin-4 0 101.6 0.020899 6878400.0 17371.0 25523.0 20857.0 20586.0 24462.0 17118.0 23464.0 24039.0 15474.0 19734.0 False True 20311.56720711099 28056.754764369307 21354.309980612983 19432.633160712496 19668.846701936287 16220.30194548325 21241.320055350992 23408.001721425888 15700.2779760681 23311.617985741963 0.8713066257148737 1.2035524424572162 0.9160372306063815 0.8336029344937806 0.8437358022067067 0.6958033524487249 0.9111902943992467 1.0041345794076961 0.6734958502524719 1.0 14.508761520395357 -5.50751744162255 18.322525713840584 0.8496298862404295 1.0430219054580387 0.2518808016420728 0.12669102194708437 24.741019963486043 29506.662060860108 0.032063750462179866 0.06289533290857698 3.108011079959206e-06 5.50751744162255 0.1933920192176093 TIPWLEDR ddPTM_PC-9_Lapatinib_30min_R1 1 TIPWLEDR 8 0 O43707;O43707-2;K7EJH8 O43707 ACTN4 Alpha-actinin-4 0 91.853 0.038764 8373300.0 20011.0 27089.0 26852.0 25470.0 28672.0 29648.0 34267.0 36480.0 23331.0 23767.0 False True 19725.639470432037 27026.277084843197 24644.332211717476 27343.148765429243 26985.569331320858 28380.0241528636 36041.17759028128 38174.993976787504 20703.21709367823 27875.094282463146 0.7076438655435108 0.9695492618242386 0.8840986136940812 0.9809168172977782 0.9680888989243022 1.0181140148005927 1.2929526704042613 1.369501878270032 0.7427137961898517 1.0 14.766689064245602 -6.088138233626189 0.9084010516574427 1.1190024767227746 0.8270458386610375 0.24452286463903383 0.17157285307543074 0.8599285659511544 1.466760347377516 0.08086078311118475 0.16272330147114625 8.163224988884868e-07 6.088138233626189 -0.2919566380617371 TIPWLEDRVPQK ddPTM_PC-9_Lapatinib_30min_R1 2 TIPWLEDRVPQK 12 1 O43707;O43707-2;K7EJH8 O43707 ACTN4 Alpha-actinin-4 0 ; 145.23 0.0001391 6651500.0 44905.0 46682.0 51216.0 40500.0 47598.0 53160.0 40453.0 38374.0 43013.0 35485.0 False True 44264.64646543155 46573.9106971335 47005.218179477226 43478.50510403944 44798.379221268486 50886.4707220126 42547.45840195084 40156.99613117444 38168.42299302997 41618.5349692096 1.0635801211690803 1.1190665584838584 1.129429909396206 1.0446909084187104 1.0764045215529912 1.2226876981532302 1.0223199455105396 0.9648825015316748 0.9171015515387049 1.0 15.344938560628071 -7.508079233522602 6.446472148426141 0.962095476365798 1.1077396903947654 0.6520240094615919 0.0492204817814978 0.09810058773065652 18.096465445997524 0.02233794093113151 0.013983309496249844 3.1039932379560616e-08 7.508079233522602 0.14564421402896743 TIQAPTQVPVVVS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 TIQAPTQVPVVVSPR 15 0 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 TIQAPTQVPVVVS(1)PR;TIQAPTQVPVVVS(1)PR 167.95 2.4627e-05 17227900.0 40853.0 47790.0 64266.0 89124.0 63451.0 58440.0 55753.0 73137.0 54719.0 61339.0 True False 53843.404204811945 63237.18291561419 63413.79084934158 68577.83875207383 54641.923893984225 54785.73756163082 60714.9089921276 61835.35717106534 57611.33462894749 59191.540280138564 0.9096469520810703 1.0683483250533543 1.0713319935453642 1.1585749995271672 0.9231373881365115 0.9255670202590405 1.02573625732291 1.0446654518266336 0.9733035220284458 1.0 15.85310337857916 -6.286301262491002 24.99950714427688 0.9836598902106795 1.0545276905727052 0.20547329922631685 0.06722632256909296 1319.2591653185052 1326557.8493337377 0.02186360248827063 0.024803565120122856 5.172479016447985e-07 6.286301262491002 0.07086780036202578 TIQAPTQVPVVVS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TIQAPTQVPVVVSPR 15 0 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 TIQAPTQVPVVVS(1)PR;TIQAPTQVPVVVS(1)PR;TIQAPTQVPVVVS(1)PR 153.92 0.00016547 13083800.0 66815.2 67745.0 73181.2 87521.0 84666.0 70237.0 92083.0 69411.7 63485.6 56967.4 True False 78125.69369964658 74470.27588889227 74926.11734924655 82617.48211691028 68076.30507996645 66553.64807482802 83360.23161681237 67589.71642277538 64413.956797044644 67295.13866630972 1.1609411206809654 1.1066219249233031 1.1133956900033428 1.2276887120565732 1.01160806603773 0.9889815132834711 1.2387259060444642 1.0043774002447095 0.9571858840569193 1.0 16.03821466929853 -7.563552646002755 0.503935713145975 0.9771471497865319 1.1423614138686158 0.28842828034874146 0.0824504897944358 1.2895026114006138 0.7314569628110563 0.08588636454236506 0.06426488373860596 2.731790270995998e-08 7.563552646002755 0.16521426408208384 TIQAPTQVPVVVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 TIQAPTQVPVVVSPR 15 0 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 TIQAPTQVPVVVS(1)PR;TIQAPTQVPVVVS(1)PR 191.35 9.769e-08 18790500.0 58595.0 56813.0 68108.0 58963.0 61435.0 52113.0 48926.0 47473.0 59211.0 37860.0 True False 57759.42455499303 56681.45298908033 62508.423144482935 63299.33571480191 57821.51408585719 49884.24847133639 51459.14888324342 49678.768888707025 52542.03366052812 44404.050554721034 1.3007692729250813 1.276492848760032 1.4077189437357995 1.4255306649738047 1.3021675582186187 1.1234166218656532 1.1588841162098058 1.1187891254984887 1.183271188194381 1.0 15.43840366532906 -6.693229478720428 4.011928878606802 1.1257666377835507 1.3523323357862314 0.7741587606741775 0.06124028558304231 0.11030329422938237 3.4993084663599725 0.021607324555527475 0.0210801687689751 2.0266115865841553e-07 6.693229478720428 0.22656569800268067 TIQEVLEEQS(ph)EDEDR ddPTM_PC-9_AZD4547_30min_R2 4 TIQEVLEEQSEDEDR 15 0 M0R0Q7;P18858-2;P18858;P18858-3 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 TIQEVLEEQS(1)EDEDR;TIQEVLEEQS(1)EDEDR;TIQEVLEEQS(1)EDEDR;TIQEVLEEQS(1)EDEDR 274.6 7.247199999999999e-75 4461200.0 22102.039999999997 28004.92 28639.75 25660.1 22673.75 33013.3 26962.96 40613.979999999996 30650.870000000003 24030.850000000002 True False 29130.028969008938 37056.96272394104 28259.968202119773 19744.560389593036 19525.891189913862 30948.973132159237 29362.611205825284 34338.02260741488 32271.01241320869 23189.537255921467 1.256171205467697 1.5980035442267617 1.2186516656300923 0.8514426213723281 0.842012972247987 1.3346093451802878 1.2662008250435233 1.4807549727473168 1.391619507412476 1.0 14.501186411036247 TIQEVLEEQS(ph)EDEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TIQEVLEEQSEDEDR 15 0 M0R0Q7;P18858-2;P18858;P18858-3 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 TIQEVLEEQS(1)EDEDR;T(0.001)IQEVLEEQS(0.999)EDEDR 112.57 0.00030443 3280400.0 16131.2 26431.0 24544.5 18273.0 17698.4 14134.2 20528.5 12711.6 14111.2 14644.2 True False 18861.89355427718 29054.89500360635 25129.733965534615 17249.223051865316 14230.525569027439 13392.977670162942 18583.891866530557 12377.933969053513 14317.549604232403 17299.077536576595 1.0903410031197454 1.6795632566056569 1.4526632366610959 0.9971180842096425 0.8226175955879086 0.774201840638339 1.0742706845054248 0.7155256656247722 0.8276481548776142 1.0 14.078407488573953 -5.846160130470587 3.900333633079341 0.864143057845792 1.4374781510533585 0.6752488147475059 0.1665974192762251 0.117233547169109 3.407910919409039 0.046459349902563805 0.07322736498245806 1.4250820489685227e-06 5.846160130470587 0.5733350932075665 TIQEVLEEQS(ph)EDEDR ddPTM_PC-9_Lapatinib_30min_R1 2 TIQEVLEEQSEDEDR 15 0 M0R0Q7;P18858-2;P18858;P18858-3 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 TIQEVLEEQS(1)EDEDR;TIQEVLEEQS(1)EDEDR 194.51 1.3516e-09 5191100.0 16638.4 20945.7 16780.4 16447.6 19000.1 18683.6 18410.1 17838.8 19037.8 18399.2 True False 16401.133364891124 20897.201518549984 15400.780286217187 17657.211371585166 17882.551473633837 17884.545981598832 19363.284896688863 18667.655771741134 16893.56248707846 21579.47720460706 0.7600338603842359 0.9683831225572316 0.7136771730007079 0.8182409241969718 0.8286832578972786 0.8287756840457938 0.8973009268526182 0.8650652467037397 0.7828531862427051 1.0 14.397372293334742 -7.147277565257469 5.665031822238842 0.874858258786768 0.8212405929628763 0.14132909269295957 0.07859682823401509 0.5847719809308335 25.242068308641166 0.029246598463235563 0.02255514487272927 7.123975787505183e-08 7.147277565257469 -0.053617665823891714 TIQEVLEEQS(ph)EDEDREAK ddPTM_PC-9_AZD4547_30min_R2 4 TIQEVLEEQSEDEDREAK 18 1 M0R0Q7;P18858-2;P18858;P18858-3 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 TIQEVLEEQS(1)EDEDREAK;TIQEVLEEQS(1)EDEDREAK;TIQEVLEEQS(1)EDEDREAK;T(0.001)IQEVLEEQS(0.999)EDEDREAK 112.88 7.935800000000001e-05 183146400.0 115044.4 119549.2 126607.4 140114.0 148938.1 133636.5 145174.8 136986.2 116860.7 126453.5 True False 151626.1261278257 158191.14098797555 124928.50315219456 107812.88203972063 128260.61567374237 125280.18852934407 158095.07595914675 115818.13041971871 123037.71802615262 122026.40145445011 1.2425682009841497 1.2963681555997124 1.023782572157778 0.8835209491936457 1.0510890606048018 1.0266646154939554 1.2955809076952933 0.9491235424405364 1.0082876865960848 1.0 16.89683379539418 -5.264083051411349 24.789622024952997 1.0328616752633295 1.2694681922924462 0.474047153153201 0.10095552839061776 171.4831271717525 1608011.9246156705 0.027446042756276906 0.0616594944310102 5.4439853595394785e-06 5.264083051411349 0.23660651702911673 TIQEVLEEQS(ph)EDEDREAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 TIQEVLEEQSEDEDREAK 18 1 M0R0Q7;P18858-2;P18858;P18858-3 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 TIQEVLEEQS(1)EDEDREAK;TIQEVLEEQS(1)EDEDREAK;TIQEVLEEQS(1)EDEDREAK;TIQEVLEEQS(1)EDEDREAK;TIQEVLEEQS(1)EDEDREAK;TIQEVLEEQS(1)EDEDREAK 114.63 6.573e-05 183148700.0 111968.5 125259.5 105267.9 126143.5 134161.4 113724.4 133446.3 114844.5 101489.4 88560.1 True False 130922.55557132026 137694.435348804 107777.88596673409 119076.08865774462 107873.43675566831 107760.4922636357 120805.30039645331 111829.9535628058 102973.49047591876 104615.34508863438 1.2514660775663202 1.3161973057790295 1.0302301815801522 1.1382277481076846 1.0311435350547622 1.0300639181788926 1.1547569842082168 1.0689631952947143 0.9843057955663715 1.0 16.674734957566237 -5.261531404935408 24.99999992557538 1.0620081915588575 1.2838317065494065 0.7396127542635336 0.05424093413271488 3.8170400687542814 1037318.4310682466 0.01386747762642894 0.032222415531761354 5.4760650071525385e-06 5.261531404935408 0.22182351499054898 TIQEVLEEQS(ph)EDEDREAK ddPTM_PC-9_Lapatinib_30min_R1 5 TIQEVLEEQSEDEDREAK 18 1 M0R0Q7;P18858-2;P18858;P18858-3 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 TIQEVLEEQS(1)EDEDREAK;TIQEVLEEQS(1)EDEDREAK;TIQEVLEEQS(1)EDEDREAK;TIQEVLEEQS(1)EDEDREAK;TIQEVLEEQS(1)EDEDREAK 131.35 1.9249e-05 182709900.0 132654.2 133703.8 125485.0 130056.4 125824.2 123350.8 116201.4 118403.7 110544.1 97082.1 True False 130762.52678219917 133394.21706583723 115168.1076861079 139621.1815114317 118423.46793589495 118075.37382875897 122217.73991418305 123905.16815595783 98093.45937702092 113862.61163123298 1.1484237442726148 1.1715366014777642 1.0114655375998491 1.226225004952662 1.0400557851196424 1.0369986436914855 1.0733790325309756 1.0881988949739683 0.8615071968901992 1.0 16.796934570304487 -7.320773890505738 0.5948484160979584 0.9603758382837064 1.1387335670547885 0.40598448158661826 0.07504649785231567 0.8519708424055349 0.6165999335286957 0.06726161375717694 0.04863390888520733 4.777779574874665e-08 7.320773890505738 0.17835772877108202 TIQEVLEEQS(ph)EDEDREAKR ddPTM_PC-9_AZD4547_30min_R2 1 TIQEVLEEQSEDEDREAKR 19 2 M0R0Q7;P18858-2;P18858;P18858-3 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 TIQEVLEEQS(1)EDEDREAKR 45.735 0.029013999999999998 45185000.0 46537.0 42192.0 57104.0 69295.0 70063.0 68439.0 60773.0 60500.0 50021.0 61066.0 True False 61334.7979702674 55829.73889047069 56346.76364890925 53320.10834707776 60335.96182541199 64159.49851095917 66181.67926709891 51151.115151694095 52665.00794010459 58928.09792704381 1.040841298597542 0.9474213635673586 0.9561951875431243 0.9048333515378513 1.0238912157000417 1.0887759959670193 1.1230920663523778 0.8680258985284398 0.8937164068201681 1.0 15.846668079380445 -7.796590291205889 24.999972630688394 0.9106533535005951 1.0067797523909092 0.26172107206854733 0.0694745050348049 268.6174535605342 191042.27605338173 0.041470442411048775 0.019923086695825605 1.597385393023351e-08 7.796590291205889 0.09612639889031416 TIQEVLEEQS(ph)EDEDREAKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TIQEVLEEQSEDEDREAKR 19 2 M0R0Q7;P18858-2;P18858;P18858-3 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 TIQEVLEEQS(1)EDEDREAKR;TIQEVLEEQS(1)EDEDREAKR;TIQEVLEEQS(1)EDEDREAKR 43.162 0.035379 39974800.0 48889.0 48619.0 66351.0 67731.0 80353.0 77779.0 74711.0 92162.0 72256.0 59254.0 True False 57164.942098235515 53445.57300822281 67933.05947756876 63936.25165686482 64608.40646883685 73700.13231789586 67633.83321920094 89742.8451537109 73312.60730507782 69996.28114559408 0.8166854176057003 0.7635487504979677 0.9705238387774664 0.9134235506580093 0.9230262724165258 1.0529149707910577 0.9662489508338423 1.2821087589931164 1.047378605051684 1.0 16.094990654245187 -6.200954155403199 0.6226997515089137 1.108617707312159 0.7810246777467187 0.5542310118421381 0.0902192524916287 0.6916669096884559 0.5517544638233242 0.06083796436295195 0.1277240502751312 6.295726377204547e-07 6.200954155403199 -0.32759302956544034 TIQEVLEEQS(ph)EDEDREAKR ddPTM_PC-9_Lapatinib_30min_R1 1 TIQEVLEEQSEDEDREAKR 19 2 M0R0Q7;P18858-2;P18858;P18858-3 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 TIQEVLEEQS(1)EDEDREAKR 46.818000000000005 0.026675 40135000.0 22736.0 20796.0 21639.0 20722.0 23424.0 18904.0 16497.0 17087.0 22308.0 18470.0 True False 22411.78047072824 20747.848139702437 19859.924948955548 22245.96500656558 22046.24637335589 18095.519987376338 17351.13393955907 17880.92439916031 19795.438126345813 21662.514890271996 1.03458811611909 0.9577765206300997 0.916787595971789 1.0269336279397363 1.0177140782142622 0.8353379133972348 0.8009750496398255 0.8254316033818453 0.9138107106500071 1.0 14.402913120607794 -6.7632585646935 24.99990386909512 0.8595670183633601 0.9868276492414302 0.4554424940513573 0.06200178291939218 41.14823068084132 565466.4805237819 0.021211262515812197 0.019675157996539423 1.7248106905129389e-07 6.7632585646935 0.12726063087807005 TIQFVDWCPTGFK ddPTM_PC-9_Lapatinib_30min_R1 2 TIQFVDWCPTGFK 13 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;Q6PEY2;Q9NY65-2;Q9NY65;C9J2C0;V9GZ17;Q71U36-2;Q71U36 Q9BQE3;Q71U36-2 TUBA1C;TUBA3E;TUBA8;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-8 chain;Tubulin alpha-1A chain 0 ; 184.1 0.0002477 4088200.0 46891.0 39902.4 56231.0 41367.1 50932.0 46890.0 48298.0 45356.0 47809.0 40280.0 False True 46222.325741243774 39810.00844439614 51607.90423793707 44409.37453060027 47936.27989616472 44884.62400592871 50798.63411607101 47463.40534021855 42424.24696891099 47242.34433027375 0.9784088066862437 0.8426763956945541 1.0924077746257352 0.9400332511048131 1.0146888469598296 0.950093070998719 1.0752775891250241 1.0046792980551378 0.8980131610811017 1.0 15.52779293763214 -5.24984750808829 24.987373986055832 0.9967982534957889 0.9105426156594204 0.22946600849784393 0.06329803231694602 1041.3843323053752 2244792.4819702148 0.015238057407272304 0.03960335097515898 5.625388122964439e-06 5.24984750808829 -0.08625563783636847 TIQLYEMY(ph)FK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TIQLYEMYFK 10 0 Q9P2D1;Q9P2D1-2 Q9P2D1 CHD7 Chromodomain-helicase-DNA-binding protein 7 1 TIQLYEMY(1)FK 69.598 0.039794 3594800.0 3556.7 4540.1 4058.1 3446.0 2995.7 3984.8 7826.5 4473.4 3225.8 2471.8 True False 4158.779061972924 4990.811123524393 4154.860494429952 3252.9317920827375 2408.7140898123853 3775.830073160515 7085.1172610469 4355.9779899590885 3272.9712223859688 2919.9177732419666 1.424279512280737 1.709230023276692 1.4229374993039055 1.11404910846891 0.8249253153242069 1.2931289051226378 2.4264783501695453 1.4918152935254314 1.120912120327282 1.0 11.51171202712137 TIQNSSVS(ph)PTSSSSSSSSTGETQTQSSSR ddPTM_PC-9_Lapatinib_30min_R1 2 TIQNSSVSPTSSSSSSSSTGETQTQSSSR 29 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 TIQNS(0.005)S(0.014)VS(0.932)PT(0.047)S(0.001)SSSSSSSTGETQTQSSSR;TIQNS(0.013)S(0.038)VS(0.947)PT(0.002)SSSSSSSSTGETQTQSSSR 175.61 1.9438999999999997e-49 4396300.0 19439.2 14409.599999999999 19923.2 16006.8 17970.3 16533.6 14987.8 14426.6 19080.0 12321.199999999999 True False 19161.99344328732 14376.23545652318 18285.191401776017 17183.993469119476 16913.322284969145 15826.496469704047 15763.794948131379 15096.912502892603 16931.009478692766 14450.90300303299 1.3260066474230403 0.9948330186359884 1.265332097097204 1.1891293897352198 1.1703989903896896 1.0951908310769467 1.0908518965785623 1.0447037461758637 1.1716229411504073 1.0 13.818872025721328 -6.762966646336709 3.1524977316117866 1.0815569333461483 1.1845731211522827 0.27445492354598133 0.08874686892626313 0.3719262339311827 7.658873382497837 0.03069408054845164 0.02854178263589079 1.725970440822411e-07 6.762966646336709 0.10301618780613442 TIQNSSVSPT(ph)SSSSSSSSTGETQTQSSSR ddPTM_PC-9_AZD4547_30min_R2 1 TIQNSSVSPTSSSSSSSSTGETQTQSSSR 29 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 TIQNS(0.001)S(0.002)VS(0.149)PT(0.779)S(0.051)S(0.018)S(0.001)SSSSSTGETQTQSSSR 158.47 6.6353e-29 0.0 5826.7 6953.2 10994.0 16759.0 10859.0 9200.1 8764.4 11775.0 7774.3 8115.6 True False 7679.469397111053 9200.685922763101 10848.212376648013 12895.47147396891 9351.415289984001 8624.816292620804 9544.414621107446 9955.444312581782 8185.233626451983 7831.475314196385 0.9805903854654582 1.1748343132850974 1.3852067383757292 1.646620969435075 1.1940809253439602 1.1013015998385773 1.2187249832488085 1.2712093077194797 1.0451713499772295 1.0 12.935068396518476 -6.505961724173802 24.678772320915755 1.1496965451748813 1.3101562460580016 0.16785446625328326 0.17348593255950012 1274.80116816252 1859699.3880586042 0.05842280178594961 0.06462091312103292 3.119164474384686e-07 6.505961724173802 0.16045970088312034 TIS(ph)AQDTLAYATALLNEK ddPTM_PC-9_AZD4547_30min_R2 2 TISAQDTLAYATALLNEK 18 0 Q9UPU5;A0A0U1RQI9 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 T(0.098)IS(0.892)AQDT(0.01)LAYATALLNEK;T(0.087)IS(0.913)AQDTLAYATALLNEK 179.84 9.895299999999998e-09 35757000.0 147245.0 160619.0 182936.0 183116.0 201272.0 199158.0 208813.0 222310.0 180775.0 185568.0 True False 194065.84711373833 212535.95067426297 180510.1491117408 140901.43531399788 173328.85700761227 186704.61877651015 227396.95247561805 187957.09767558824 190330.39744052282 179071.32080250318 1.083734940045327 1.1868787794817672 1.0080349455333748 0.7868453456564233 0.9679319738685335 1.0426271383926726 1.2698680696414417 1.0496214404029842 1.0628748176288778 1.0 17.450174775194156 -7.009587982949408 24.437766181660884 1.1078006845410886 1.004629791387721 0.11419501561314915 0.11469554950421014 750.109131964418 1911872.5285447773 0.04591117074007004 0.03824141762821113 9.781647700431206e-08 7.009587982949408 -0.1031708931533677 TIS(ph)AQDTLAYATALLNEK ddPTM_PC-9_Lapatinib_30min_R1 1 TISAQDTLAYATALLNEK 18 0 Q9UPU5;A0A0U1RQI9 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 T(0.071)IS(0.924)AQDT(0.006)LAYATALLNEK 220.89 4.8759e-28 35374000.0 119250.0 135940.0 107410.0 126750.0 175260.0 161280.0 160730.0 145860.0 176780.0 132290.0 True False 117549.4731322281 135625.23928212872 98579.16441459037 136071.6178256052 164951.55137441758 154382.4303620427 169051.8129420699 152637.18808810922 156869.17482407263 155156.15023465554 0.7576204549703526 0.874120936082852 0.6353545397040395 0.8769978993408434 1.0631325353519512 0.9950132826095346 1.0895592130018616 0.9837649868037027 1.0110406489644552 1.0 17.24336135942577 -6.049105399276921 4.530608503180245 1.0229129619719606 0.764883791854815 0.7912048375305079 0.06201833803242669 0.08978546922120557 3.987031211529261 0.017837215954092735 0.024250764762760457 8.930887130125584e-07 6.049105399276921 -0.25802917011714555 TIS(ph)DGTISASK ddPTM_PC-9_AZD4547_30min_R2 3 TISDGTISASK 11 0 A0A075B6Q2;S4R347;Q5T0N5-3;Q5T0N5-4;Q5T0N5-2;Q5T0N5-5;Q5T0N5 A0A075B6Q2 FNBP1L Formin-binding protein 1-like 1 T(0.014)IS(0.981)DGT(0.005)ISASK;T(0.076)IS(0.462)DGT(0.462)ISASK;T(0.002)IS(0.891)DGT(0.106)ISASK 171.49 0.00014423 196826000.0 134853.0 147591.0 225634.0 285016.0 330336.0 296577.0 277814.0 291966.0 248001.0 291522.0 True False 177733.4488833503 195296.9044506887 222641.94573336322 219309.96465330425 284474.54841441754 278031.99330622517 302538.90780296986 246849.36341123178 261109.8265559238 281315.90351239144 0.631793107550073 0.6942263199922013 0.7914303562420397 0.7795860877934477 1.011228106419113 0.9883266101732439 1.0754418929950171 0.877481010953078 0.9281730015822671 1.0 18.101831588660374 -5.875744383872341 1.3787028912117012 0.9806495852729313 0.6662824567864072 0.8126057974699766 0.060894057979726975 0.18972546219978562 0.7309386998112724 0.022267947986571668 0.04645101175360911 1.3312377245214562e-06 5.875744383872341 -0.31436712848652415 TIS(ph)DGTISASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TISDGTISASK 11 0 A0A075B6Q2;S4R347;Q5T0N5-3;Q5T0N5-4;Q5T0N5-2;Q5T0N5-5;Q5T0N5 A0A075B6Q2 FNBP1L Formin-binding protein 1-like 1 T(0.227)IS(0.763)DGT(0.01)IS(0.001)ASK;T(0.355)IS(0.613)DGT(0.03)IS(0.003)ASK 145.14 0.00019553 91008000.0 79516.0 81730.0 111463.0 141018.0 152306.0 132874.0 155332.0 133972.0 127811.0 114824.0 True False 92976.48828741214 89843.61426524712 114120.70064578149 133117.21864652456 122462.73263776918 125905.8535286916 140617.82845370698 130455.37695506756 129679.99408034385 135640.68225371637 0.6854616678608214 0.6623648065791524 0.8413456696739281 0.9813959678964777 0.9028466283345745 0.928230759656489 1.036693609301381 0.9617717545172054 0.9560553067535961 1.0 17.049430420485912 -5.461202001131466 2.5815344178002793 0.9642149938333912 0.6694816120440348 0.910813267518625 0.036431670712064025 0.0777735803302086 1.0080788437286452 0.010717562837586691 0.02617301569079531 3.4577851025889332e-06 5.461202001131466 -0.2947333817893564 TIS(ph)DGTISASK ddPTM_PC-9_Lapatinib_30min_R1 3 TISDGTISASK 11 0 A0A075B6Q2;S4R347;Q5T0N5-3;Q5T0N5-4;Q5T0N5-2;Q5T0N5-5;Q5T0N5 A0A075B6Q2 FNBP1L Formin-binding protein 1-like 1 T(0.468)IS(0.532)DGTISASK;T(0.011)IS(0.986)DGT(0.003)ISASK;T(0.019)IS(0.973)DGT(0.009)ISASK 148.13 0.00012132 239104000.0 144349.0 155798.0 181002.0 149356.0 173760.0 179583.0 176134.0 152038.0 185176.0 139079.0 True False 142290.55678963521 155437.2593032007 166120.71424792538 160340.1384770105 163539.77842530387 171902.65371841958 185253.3566897193 159102.24052200717 164319.52889027327 163118.61983888102 0.872313393346397 0.9529093579674257 1.0184043637201545 0.9829664978491424 1.002581916073339 1.0538505897623147 1.1356971808166454 0.9753775545621892 1.007362182518332 1.0 17.315561948184822 -3.4842604279845037 0.7063306765376763 1.032503581269629 3.687179820363942e-14 0.5505996012717542 0.04299324683254852 12.32472288771853 1.1261299097108863 0.01810346618574783 15.392043620458535 0.0003278986072567249 3.4842604279845037 -1.0325035812695922 TIS(ph)DGTISASKQESGK ddPTM_PC-9_AZD4547_30min_R2 1 TISDGTISASKQESGK 16 1 A0A075B6Q2;S4R347;Q5T0N5-3;Q5T0N5-4;Q5T0N5-2;Q5T0N5-5;Q5T0N5 A0A075B6Q2 FNBP1L Formin-binding protein 1-like 1 T(0.267)IS(0.724)DGT(0.004)IS(0.005)ASKQESGK 51.942 0.039934 4593100.0 4876.0 2232.9 13707.0 41007.0 31026.0 10789.0 8355.6 9330.4 7502.8 12553.0 True False 6426.466572899499 2954.6412582606163 13525.236224005299 31553.469701834416 26718.575447743224 10114.362124442756 9099.23221305798 7888.601071262261 7899.382690730217 12113.523290835836 0.5305200162335323 0.2439126245372287 1.1165402417839454 2.6048135578940403 2.2056816011536835 0.8349645170612342 0.7511631417707978 0.6512226774872487 0.6521127256762932 1.0 13.564330922115078 -6.969891814369972 24.98963450560098 0.7429166953756375 1.355515977747166 0.1543232152582661 0.6587661776444381 435.99980818717086 361876.34214184724 0.2697374622726256 0.23788354195106304 1.0717862610377525e-07 6.969891814369972 0.6125992823715284 TIS(ph)DGTISASKQESGK ddPTM_PC-9_Lapatinib_30min_R1 1 TISDGTISASKQESGK 16 1 A0A075B6Q2;S4R347;Q5T0N5-3;Q5T0N5-4;Q5T0N5-2;Q5T0N5-5;Q5T0N5 A0A075B6Q2 FNBP1L Formin-binding protein 1-like 1 T(0.177)IS(0.777)DGT(0.046)IS(0.001)ASKQESGK 88.28299999999999 0.0019044 6822600.0 125580.0 14433.0 31277.0 21616.0 11216.0 18699.0 8667.4 5935.3 29787.0 11781.0 True False 123789.20617144836 14399.581275260873 28705.525792711454 23205.712748862155 10556.296931504425 17899.28735949799 9116.15556208609 6211.075705877926 26432.074388984358 13817.330152804243 8.95898156897736 1.0421391915817009 2.0775016211714123 1.6794643025991913 0.7639896285869678 1.2954230058594431 0.6597624476850151 0.44951344704008406 1.9129653917707061 1.0 13.754191258125546 -4.760708343662282 24.999747404983733 1.2052473888276336 8.958990519390813 0.9536575065881736 0.512526582064493 3.508787293784504 119911.85895142538 0.13296231045586362 0.7746574001911478 1.7349687483549865e-05 4.760708343662282 7.75374313056318 TIS(ph)EPDEQR ddPTM_PC-9_AZD4547_30min_R2 1 TISEPDEQR 9 0 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 T(0.196)IS(0.804)EPDEQR 145.28 0.00050219 25458000.0 52355.0 57323.0 57438.0 46491.0 56086.0 61244.0 55801.0 72817.0 64738.0 45074.0 True False 69002.80094834963 75851.53873763877 56676.334590677485 35773.218228789796 48299.42701483037 57414.40299836614 60767.180899139275 61564.805818196764 68159.91851475347 43495.97297945782 1.5864181491224052 1.7438749737466903 1.3030248712322048 0.8224489712113048 1.1104344541882327 1.31999353194103 1.3970760219075513 1.4154139245780857 1.5670397474944147 1.0 15.408594216568234 -5.320782819416583 5.957577246176275 1.2432765075806929 1.6644108150648507 0.3998101112369523 0.20794432812437294 0.21512843159836242 16.130935518365046 0.05981203856441553 0.12854738400697896 4.77768134675733e-06 5.320782819416583 0.4211343074841578 TIS(ph)EPDEQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TISEPDEQR 9 0 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 T(0.063)IS(0.937)EPDEQR 103.43 0.0028575 18232000.0 16260.0 28489.0 28967.0 19578.0 30716.0 23221.0 21304.0 12027.0 20676.0 18079.0 True False 19012.496850361214 31317.199642758187 29657.683137959244 18481.108132732403 24697.420296650944 22003.24988176577 19285.93089239676 11711.303993659847 20978.34738485098 21356.579586714757 0.890240722919333 1.466395848436311 1.3886906851136565 0.865358989612218 1.1564314499131882 1.0302796752834562 0.9030439923251529 0.5483698335732129 0.9822896639263777 1.0 14.38239298685485 -6.751867908471687 1.0233750129269437 0.8196092487110329 1.2189366485454043 0.2898188427027566 0.2119428850875613 0.5867022460529301 1.3169545299517953 0.119988792361904 0.11008835831823192 1.770647422352298e-07 6.751867908471687 0.3993273998343714 TIS(ph)EPDEQR ddPTM_PC-9_Lapatinib_30min_R1 2 TISEPDEQR 9 0 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 T(0.21)IS(0.79)EPDEQR;TIS(1)EPDEQR 152.04 0.00012582 39503000.0 73979.0 73952.0 65099.0 53290.0 78179.0 77807.0 71296.0 77066.0 71636.0 69388.0 True False 72924.04589391292 73780.76868759729 59746.81150940699 57209.12437022871 73580.66492582779 74479.37598697584 74987.35802599287 80646.76770326486 63567.59931947776 81381.62334630171 0.8960750952779668 0.906602321922719 0.7341560545575195 0.702973497183606 0.9041434896514825 0.9151866591557793 0.9214286339177649 0.9909702508647459 0.7811050788330891 1.0 16.3124154381658 -6.4901595931525815 23.679433070823283 0.9198778558927827 0.8104559729553152 0.3070989036813673 0.08043935427863724 451.66759512286245 326879.74663703865 0.025852009702595914 0.029284417210628206 3.234747656097635e-07 6.4901595931525815 -0.10942188293746746 TIS(ph)EPDEQRSELPR ddPTM_PC-9_AZD4547_30min_R2 1 TISEPDEQRSELPR 14 1 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 T(0.203)IS(0.797)EPDEQRSELPR 91.932 0.0020500999999999996 19554000.0 16721.0 9906.0 26361.0 35886.0 34080.0 23423.0 14770.0 24174.0 13258.0 14080.0 True False 22037.930181594013 13107.92077761193 26011.43591602857 27613.03713317311 29348.580263620483 21958.35610722243 16084.501386718646 20438.46376325708 13958.79081325655 13587.06348561846 1.6219788922691474 0.9647353743129492 1.9144266120167153 2.032303533607594 2.1600385024096753 1.616122286501771 1.1838099824692552 1.5042590906335753 1.0273589159299619 1.0 13.729946065786425 -7.183547838636838 4.4926906205256225 1.2200415591193152 1.7348971218119522 0.3932602221980417 0.32853517713316 0.2852160077168614 10.679072146511656 0.1435791308116659 0.10869489117751589 6.553180969099795e-08 7.183547838636838 0.514855562692637 TIS(ph)EPDEQRSELPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TISEPDEQRSELPR 14 1 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 T(0.031)IS(0.969)EPDEQRSELPR 75.143 0.0084116 9072900.0 11574.0 10992.0 19011.0 18718.0 20622.0 22816.0 19637.0 14598.0 17241.0 13827.0 True False 13533.249603079987 12083.213116402745 19464.294339618988 17669.29114457478 16581.26713626566 21619.488794727542 17776.841200431612 14214.817967859519 17493.117008232526 16333.725645528217 0.8285464012789432 0.7397707895082002 1.1916628674945233 1.0817673522888032 1.015155237458345 1.3236103791572158 1.0883518914313641 0.8702740744118717 1.0709814397440747 1.0 13.995566279896602 -5.253742776706907 24.992560151983348 1.0823060246754865 0.7841585638652075 0.5178778953177585 0.11425123029185087 470.3273086265623 1527247.1113368813 0.030575123995859075 0.077734331461789 5.575158558307731e-06 5.253742776706907 -0.298147460810279 TIS(ph)EPDEQRSELPR ddPTM_PC-9_Lapatinib_30min_R1 1 TISEPDEQRSELPR 14 1 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 T(0.01)IS(0.99)EPDEQRSELPR 114.01 8.4757e-05 10860000.0 28076.0 17108.0 22911.0 16219.0 15566.0 20911.0 14925.0 22130.0 23372.0 13679.0 True False 27675.631091492163 17068.387477112392 21027.346019017557 17411.799364997933 14650.438483933478 20016.685275921827 15697.743471414133 23158.240589536934 20739.599241929096 16043.396923878205 1.725048081949597 1.0638886239676986 1.310654228576835 1.085293809510071 0.9131755920174539 1.2476587951352107 0.978455095631922 1.4434748887294153 1.2927187016772796 1.0 13.969692020492719 -4.755778696853995 24.98466860718532 1.15577097564363 1.7250489996572815 0.5328869371505295 0.16184187753680593 148.33258406508708 654630.7432192999 0.04052255269425559 0.3481207221596035 1.7547744532910306e-05 4.755778696853995 0.5692780240136515 TIS(ph)ETIER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TISETIER 8 0 P26639;P26639-2 P26639 TARS Threonine--tRNA ligase, cytoplasmic 1 T(0.002)IS(0.875)ET(0.123)IER 99.788 0.0050921000000000004 2427700.0 5465.8 6685.4 8972.0 9834.3 7619.5 6521.0 6720.1 6430.8 5769.5 6704.7 True False 6391.051985529172 7349.082329730615 9185.926506499474 9283.316054230778 6126.513672038412 6179.0272804355845 6083.523478689233 6261.9983139958185 5853.868022678356 7920.209035623999 0.8069297106658561 0.9278899454137467 1.159808594089178 1.1721049296143211 0.7735292900076507 0.7801596211215107 0.7681013785528122 0.7906354852290162 0.7391052428475653 1.0 12.95132279207283 -6.284611298676927 24.676731846712304 0.7946744535979711 1.0205641548486701 0.41765001814582237 0.11966978786663071 640.9026420750076 682521.5597056176 0.03884329106790845 0.044074913421734675 5.192645820920734e-07 6.284611298676927 0.22588970125069907 TIS(ph)ETIER ddPTM_PC-9_Lapatinib_30min_R1 1 TISETIER 8 0 P26639;P26639-2 P26639 TARS Threonine--tRNA ligase, cytoplasmic 1 T(0.036)IS(0.901)ET(0.063)IER 93.096 0.007481399999999999 1695700.0 9061.2 6988.9 9722.0 8338.3 7818.9 7800.1 6204.1 5527.2 8073.4 7933.7 True False 8931.985626379437 6972.717631446734 8922.694688005262 8951.526397753381 7359.007674548849 7466.5079059211885 6525.317941105559 5784.0138900356305 7164.08867532904 9305.02947400926 0.9599094394411317 0.7493493331668512 0.9589109537941892 0.9620094619535295 0.7908634459572617 0.8024163627612985 0.701267842227908 0.6216008134301451 0.7699157423777883 1.0 13.18379500474121 -6.466011746028203 3.618159318745197 0.7527260451404225 0.8995682284311789 0.22517340403172614 0.10859635681228853 0.3185162677036259 8.325140061756212 0.03531271003422931 0.03897630455124164 3.4197019338431997e-07 6.466011746028203 0.14684218329075638 TIS(ph)NPEVVMK ddPTM_PC-9_AZD4547_30min_R2 4 TISNPEVVMK 10 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6;F8W9I4;E9PFY5 A8MQ02 MLLT4 Afadin 1 TIS(1)NPEVVMK;T(0.023)IS(0.977)NPEVVMK;T(0.019)IS(0.981)NPEVVMK;T(0.001)IS(0.999)NPEVVMK 119.39 0.00079395 92016400.0 432379.0 440120.0 589873.0 730409.0 623431.0 485966.0 489678.0 551634.0 541579.0 499869.0 True False 569866.527958103 582380.182984309 582050.8986038293 562024.4897565576 536878.3668523822 455578.46919704863 533258.3933680161 466391.640588259 570205.7602845582 482368.738458282 1.1813919156110244 1.2073340093424743 1.2066513689592435 1.1651345639704316 1.1130040652475128 0.9444610168004277 1.1054994879485445 0.9668778330845235 1.1820951791092755 1.0 18.879776885960396 -6.376782234900104 2.899710863383272 1.0411829815270142 1.1948330216749958 0.5360596193054701 0.06536388359713143 0.1998158667277034 3.23726002059265 0.02029513123088765 0.023567546223574997 4.1996951344039837e-07 6.376782234900104 0.15365004014798167 TIS(ph)NPEVVMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TISNPEVVMK 10 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6;F8W9I4;E9PFY5 A8MQ02 MLLT4 Afadin 1 TIS(1)NPEVVMK;T(0.002)IS(0.998)NPEVVMK;T(0.011)IS(0.989)NPEVVMK 97.69 0.0044453 118501000.0 564860.0 562770.0 583800.0 646170.0 741810.0 671070.0 629610.0 710850.0 625180.0 442722.0 True False 660479.6415064592 618638.0863826403 597720.0060738282 609967.1898114049 596457.6556276401 635877.9078487813 569968.78281834 692190.9407078334 634322.0747756404 522983.9940145769 1.2629060335793947 1.1829006116110645 1.142903058056435 1.1663209520603486 1.1404893122044866 1.2158649502207477 1.0898398217564829 1.3235413485494554 1.2128900349442822 1.0 18.99640726773665 -4.77202590251846 4.353799797324899 1.1713314936330252 1.2702812002675345 0.1155864992301795 0.08041582446017144 0.4829229572364918 19.26084987075371 0.019313731152517534 0.1490579554509558 1.690340112099132e-05 4.77202590251846 0.0989497066345093 TIS(ph)NPEVVMK ddPTM_PC-9_Lapatinib_30min_R1 4 TISNPEVVMK 10 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6;F8W9I4;E9PFY5 A8MQ02 MLLT4 Afadin 1 T(0.001)IS(0.999)NPEVVMK;T(0.221)IS(0.779)NPEVVMK;T(0.002)IS(0.998)NPEVVMK;T(0.002)IS(0.998)NPEVVMK 127.79 0.00026513 132492000.0 955260.0 934195.0 994140.0 827906.0 883439.0 755235.0 832761.0 726899.0 902760.0 706700.0 True False 941637.8172267696 932031.9288742697 912405.6466913756 888792.9690534531 831476.8549279011 722935.3595887737 875877.2898491336 760673.3812152628 801081.662315759 828852.1533814417 1.1360745259395175 1.1244851389622248 1.100806269211057 1.072317862030608 1.003166670359426 0.8722126818871585 1.056735252814202 0.917743144072158 0.9664952416997551 1.0 19.660755258177417 -6.171501972062536 2.104159672432342 0.961697218535494 1.1210306458028572 0.6933422703219929 0.046529611517120595 0.17548973456411543 1.52642384932474 0.014961901130427346 0.02064999872958999 6.7374883607676e-07 6.171501972062536 0.15933342726736321 TIS(ph)PAESTALLQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TISPAESTALLQGR 14 0 H0Y8J2;Q03188;Q03188-2 H0Y8J2 CENPC Centromere protein C 1 T(0.024)IS(0.941)PAES(0.018)T(0.018)ALLQGR 85.287 0.0069535 8772100.0 16773.0 14825.0 21924.0 19233.0 21720.0 19360.0 21395.0 20809.0 19203.0 14361.0 True False 19612.33761814937 16296.728024988248 22446.75130723301 18155.437364227306 17464.121918324596 18344.727518667813 19368.310713613806 20262.78579895799 19483.8075464932 16964.53561838655 1.1560786607617524 0.9606350796496593 1.3231574274809332 1.07019948984339 1.029448863863776 1.0813574819451808 1.1416941288167055 1.1944203044966772 1.1485022628840016 1.0 14.05023431827972 -7.280612401217676 22.81910281003258 1.137355878257592 1.102094175140942 0.0 0.10039155063642727 1346.3169204923527 1602326.825634961 0.04137804721370316 0.027970712940032977 5.2406794766404154e-08 7.280612401217676 -0.03526170311665 TIS(ph)PPTLGTLR ddPTM_PC-9_AZD4547_30min_R2 1 TISPPTLGTLR 11 0 Q9UQ84;Q9UQ84-4 Q9UQ84 EXO1 Exonuclease 1 1 T(0.14)IS(0.539)PPT(0.3)LGT(0.022)LR 65.232 0.045208 4880800.0 19904.0 16399.0 22184.0 35981.0 27982.0 29601.0 21060.0 28536.0 18811.0 24979.0 True False 26233.057971081136 21699.656050076523 21889.825665231892 27686.13635090847 24097.182304478527 27750.044790585795 22934.299201374048 24126.41689204534 19805.31105658238 24104.492813015877 1.0883057434386623 0.9002328411722151 0.9081222258039748 1.1485882140593553 0.9996967159361511 1.1512395222687035 0.9514532987389823 1.0009095432623094 0.8216439653062505 1.0 14.55701445359621 -7.891026552756268 2.422372201733235 0.9148362877816315 1.0231757674104482 0.16549272511514312 0.0937073121964053 0.541301584832596 6.159651086017345 0.06844795231685717 0.02631003119922233 1.2852080799441677e-08 7.891026552756268 0.10833947962881674 TIS(ph)PSTSNNIPLMR ddPTM_PC-9_AZD4547_30min_R2 2 TISPSTSNNIPLMR 14 0 Q15139;F8WBA3;O94806;O94806-2 Q15139;O94806 PRKD1;PRKD3 Serine/threonine-protein kinase D1;Serine/threonine-protein kinase;Serine/threonine-protein kinase D3 1 T(0.029)IS(0.797)PS(0.021)T(0.125)S(0.029)NNIPLMR;T(0.001)IS(0.871)PS(0.084)T(0.037)S(0.007)NNIPLMR 91.307 0.0040423 51330000.0 131584.0 141032.0 188015.0 240312.0 189029.0 187461.0 146927.0 215360.0 153614.0 155088.0 True False 173424.97488277455 186617.83596892466 185521.79825318136 184911.78118338887 162785.58622804878 175739.03403560707 160003.21836468633 182081.060480477 161733.7224308036 149658.41632511365 1.1588053591722574 1.2469585109301264 1.2396349153539026 1.2355588527790633 1.0877142109697195 1.1742676312559437 1.069122754961538 1.2166443087632928 1.0806857803403311 1.0 17.19131388824829 -9.419219389348015 0.138088567218838 0.8495880390079453 1.3017247874770619 0.5423103202909154 0.05561530285424574 13.083570158574938 0.6485366297549603 1.4160759012985906 0.5946088064771015 3.808733717893098e-10 9.419219389348015 0.45213674846911656 TIS(ph)PSTSNNIPLMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TISPSTSNNIPLMR 14 0 Q15139;F8WBA3;O94806;O94806-2 Q15139;O94806 PRKD1;PRKD3 Serine/threonine-protein kinase D1;Serine/threonine-protein kinase;Serine/threonine-protein kinase D3 1 T(0.001)IS(0.993)PS(0.006)TSNNIPLMR;T(0.01)IS(0.555)PS(0.192)T(0.192)S(0.052)NNIPLMR 102.33 0.0013102 43353000.0 122541.0 118040.0 125494.0 138308.0 151131.0 99257.0 142539.0 106880.0 101880.0 90540.0 True False 143284.77100492697 129758.23110081724 128486.25289864518 130559.05116058604 121517.96545296104 94051.78818803771 129036.67402700608 104074.51324872093 103369.8022619763 106954.18528575439 1.3396836282947366 1.213213216052614 1.20132047713105 1.220700721638573 1.1361683989111406 0.8793651967592969 1.206466803353725 0.9730756488926572 0.9664867437005712 1.0 16.706633412974 -5.99817796763334 0.598987915306178 0.9912965753909426 1.3326705757006785 0.6142625859277979 0.08750274126126673 0.8283498039322373 0.5528315465824467 0.05853553227690501 0.16439450999108435 1.0042041975125106e-06 5.99817796763334 0.34137400030973586 TIS(ph)PSTSNNIPLMR ddPTM_PC-9_Lapatinib_30min_R1 2 TISPSTSNNIPLMR 14 0 Q15139;F8WBA3;O94806;O94806-2 Q15139;O94806 PRKD1;PRKD3 Serine/threonine-protein kinase D1;Serine/threonine-protein kinase;Serine/threonine-protein kinase D3 1 TIS(0.915)PS(0.061)T(0.019)S(0.005)NNIPLMR;T(0.001)IS(0.866)PS(0.123)T(0.007)S(0.002)NNIPLMR 99.161 0.0020027 39222000.0 208357.0 190393.0 214140.0 158773.0 177912.0 196806.0 170561.0 179070.0 201498.0 120950.0 True False 205385.7909720054 189952.15670621148 196534.23580430436 170449.69607120135 167447.56594845015 188389.06615719333 179391.81401861736 187390.24592717463 178803.17337199318 141856.0463442551 1.4478465759124348 1.3390487159443112 1.3854484237306084 1.201568071744756 1.1804048559346547 1.3280298655724005 1.2646046371775423 1.3209887823351394 1.260455073857586 1.0 17.11406811849264 -14.522878744540439 0.14448119685085578 5.186456182658365e-15 1.3960048245865706 0.6471988694274668 0.07061574019482009 98.36539986696 0.855783475469074 28.549853664089344 0.43348786123144023 3.000000005111041e-15 14.522878744540439 1.3960048245865655 TIS(ph)QEFLTPGK ddPTM_PC-9_AZD4547_30min_R2 1 TISQEFLTPGK 11 0 E7ETM8;E7EUA0;Q0ZGT2-4;Q0ZGT2-2;Q0ZGT2;Q0ZGT2-3;H7BXY5 E7ETM8 NEXN Nexilin 1 T(0.128)IS(0.872)QEFLTPGK 124.51 0.00050762 6032800.0 30151.0 32964.0 36724.0 33665.0 39432.0 49967.0 41750.0 47513.0 46073.0 39984.0 True False 39738.39082024051 43618.9683538461 36237.01576496467 25904.054369065176 33957.54744586508 46842.55559106788 45465.66911953308 40170.957590122984 48508.324720106306 38584.17233018243 1.029914299578099 1.1304886361324176 0.9391678913018513 0.6713647800292908 0.8800900834485912 1.2140355166935988 1.1783502502130285 1.041125289571115 1.25720785987058 1.0 15.23572153834847 -6.7576487639625045 24.999775946946922 1.1432270262740694 0.927449892108476 0.3885266618567673 0.13033090485110915 112.25269104319408 740326.4274744415 0.04788961799447876 0.04616362835339604 1.7472346592010192e-07 6.7576487639625045 -0.2157771341655934 TIS(ph)QEFLTPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TISQEFLTPGK 11 0 E7ETM8;E7EUA0;Q0ZGT2-4;Q0ZGT2-2;Q0ZGT2;Q0ZGT2-3;H7BXY5 E7ETM8 NEXN Nexilin 1 T(0.057)IS(0.943)QEFLTPGK 145.0 0.00019188 3655300.0 21924.0 29484.0 24819.0 26782.0 32919.0 21963.0 28736.0 25838.0 26268.0 21080.0 True False 25635.30018126194 32410.976667032257 25410.779086581653 25281.491368415536 26468.758261018756 20811.221616348197 26013.918049376316 25159.779877623947 26652.119805826347 24901.637130811825 1.029462442432844 1.3015600740133193 1.0204461238068498 1.015254187329463 1.0629324538774148 0.835737084554879 1.0446669796335688 1.0103664970080506 1.0702958872068928 1.0 14.603952973363375 -5.426225880044889 9.792584906514486 1.0041109419844332 1.165345982099099 0.3485141105132332 0.08662373885529873 0.4263645384319163 40.65874185500979 0.02167769626275508 0.0451731463495242 3.747780264867935e-06 5.426225880044889 0.16123504011466583 TIS(ph)QEFLTPGK ddPTM_PC-9_Lapatinib_30min_R1 1 TISQEFLTPGK 11 0 E7ETM8;E7EUA0;Q0ZGT2-4;Q0ZGT2-2;Q0ZGT2;Q0ZGT2-3;H7BXY5 E7ETM8 NEXN Nexilin 1 T(0.001)IS(0.65)QEFLT(0.349)PGK 137.81 9.5054e-05 5184400.0 25855.0 37995.0 29875.0 30195.0 42723.0 38970.0 38826.0 38295.0 34161.0 31777.0 True False 25486.30295877369 37907.02491190583 27418.792820834922 32415.641027567206 40210.117136649766 37303.343943506974 40836.22030292299 40074.325502770735 30313.42844872241 37269.612109809044 0.6838360132024532 1.0171027484863204 0.7356876358157355 0.869760622462601 1.0788981923980585 1.0009050760603182 1.0956974862685853 1.0752546977064865 0.8133550829401891 1.0 15.185712183586242 -6.131962673365087 5.251161341096109 1.0175768513275274 0.8284819905744408 0.4053506047974087 0.10995951860487477 0.23111238198387418 8.910558216304215 0.03151802595305588 0.04120326094944696 7.379676540652334e-07 6.131962673365087 -0.18909486075308657 TIS(ph)QSSSLK ddPTM_PC-9_AZD4547_30min_R2 1 TISQSSSLK 9 0 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 T(0.106)IS(0.871)QS(0.015)S(0.004)S(0.004)LK 113.22 0.0021155 35963000.0 164220.0 150880.0 149380.0 246260.0 212980.0 225400.0 145300.0 204180.0 158670.0 198100.0 True False 216438.54401180425 199649.00938078828 147399.12359684182 189488.56167907303 183411.40330240282 211305.70236809674 158231.41851660228 172628.67258963428 167056.9722687748 191164.57929694676 1.1322105005425613 1.0443828564634987 0.771058760670712 0.9912325932762351 0.9594424028601005 1.1053601202964678 0.8277235202176888 0.9030369183690687 0.8738908268632536 1.0 17.544455706925973 -7.281385397816023 24.973545765493018 0.8930825683684905 0.9898717553014543 0.18325254415189218 0.10077044867165859 1560.4575217823078 1953773.0989523365 0.043484620647505835 0.029361474674935415 5.231359937657913e-08 7.281385397816023 0.09678918693296379 TIS(ph)QSSSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TISQSSSLK 9 0 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 T(0.052)IS(0.943)QS(0.002)S(0.003)SLK 74.962 0.026666000000000002 57466000.0 20874.0 9925.2 20076.0 24182.0 46872.0 44806.0 36535.0 53100.0 41938.0 35190.0 True False 24407.555919707254 10910.508262638341 20554.68797865399 22827.160939101785 37687.76807346736 42456.29448354493 33074.140309506 51706.18126410059 42551.2639110989 41569.66843611327 0.5871481981439961 0.262463201490439 0.49446360175433324 0.5491302143577094 0.9066169996373235 1.021328677393573 0.7956315639210907 1.243843966269919 1.0236132620709786 1.0 15.343243620475825 -6.248675496134849 1.7754483863772537 1.0260638121744794 0.4211948969073246 0.81116956177232 0.12568627964132417 0.14379172104039326 0.8941000008964898 0.04390070078464378 0.058817697812951035 5.640589620011713e-07 6.248675496134849 -0.6048689152671548 TIS(ph)QSSSLK ddPTM_PC-9_Lapatinib_30min_R1 2 TISQSSSLK 9 0 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 T(0.047)IS(0.943)QS(0.007)S(0.002)S(0.001)LK;TIS(0.998)QS(0.001)SSLK 112.94 0.0021347 59771000.0 175821.0 149014.0 179948.0 174205.0 240790.0 334890.0 300810.0 309170.0 319450.0 246250.0 True False 173313.76029837766 148668.96723839254 165153.37005936736 187016.61683084414 226627.2056113541 320567.5353667192 316384.4699253663 323535.1668805754 283470.1770423693 288813.9843925003 0.6000878408396008 0.5147568167487012 0.5718330101181067 0.6475331075959507 0.7846822448298282 1.1099446449624322 1.0954610476735 1.1202198797994793 0.9814974078856628 1.0 18.13978107374382 -6.499848638681911 2.1046921992554295 1.0738357229702988 0.5686094083118122 0.9429480776419012 0.055379732070718786 0.06640292039581494 0.5890363429037975 0.020112773998226516 0.022053169588576938 3.163379976577962e-07 6.499848638681911 -0.5052263146584867 TIS(ph)VLASPSVPLLQHR ddPTM_PC-9_AZD4547_30min_R2 1 TISVLASPSVPLLQHR 16 0 A0A1B0GTU4;A0A1B0GV30 A0A1B0GTU4 1 T(0.352)IS(0.648)VLASPSVPLLQHR 144.25 1.6609e-05 6178700.0 17340.0 14044.0 22584.0 25057.0 21703.0 20522.0 22131.0 27343.0 19357.0 20256.0 True False 22853.759305594194 18583.448354611544 22284.52140387653 19280.49577679092 18689.913071049166 19238.75609582113 24100.616126572124 23117.767629632577 20380.171501901266 19546.84360544656 1.169179012576035 0.9507135131235933 1.140057282581784 0.9863738701740355 0.9561601580442063 0.9842385033694347 1.2329671538302325 1.1826854553228743 1.0426323509450144 1.0 14.254648041690107 -7.237836740720272 24.812590969744004 1.1297950565294717 1.0269759925285966 0.15546072179910997 0.09230435162204745 1083.7041502701886 1139260.2748833683 0.03463114263973659 0.026807200380173608 5.783134051893701e-08 7.237836740720272 -0.10281906400087504 TIS(ph)VLASPSVPLLQHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TISVLASPSVPLLQHR 16 0 A0A1B0GTU4;A0A1B0GV30 A0A1B0GTU4 1 T(0.112)IS(0.888)VLASPSVPLLQHR;T(0.059)IS(0.941)VLASPSVPLLQHR 108.06 0.0010972000000000002 3448500.0 30764.0 27813.0 26862.0 32094.0 32720.0 29173.0 32901.0 38899.0 29715.0 24906.0 True False 35971.73758330333 30574.09083028654 27502.491954702287 30295.877230151902 26308.750882485307 27643.116523868604 29784.379097387635 37877.942466897366 30149.525659743045 29421.26064421247 1.222644332556138 1.0391835754427758 0.93478292066701 1.0297273660879476 0.8942088240416907 0.9395626128381535 1.0123420426325815 1.2874343803601913 1.0247530187213045 1.0 14.844571444163561 -8.532992797332225 24.321747296217698 0.9999999819150087 1.0388016461255964 0.012183835974891699 0.11746247660603426 8765.451322817993 21078749.97178192 0.12046227702188252 0.03110322621119581 2.9309418538011166e-09 8.532992797332225 0.03880166421058773 TIS(ph)VLASPSVPLLQHR ddPTM_PC-9_Lapatinib_30min_R1 1 TISVLASPSVPLLQHR 16 0 A0A1B0GTU4;A0A1B0GV30 A0A1B0GTU4 1 T(0.418)IS(0.582)VLASPSVPLLQHR 118.05 7.4966e-05 4754900.0 21908.0 20200.0 18137.0 17956.0 24172.0 19129.0 21962.0 18198.0 23891.0 20168.0 True False 21595.587902564854 20153.228141084295 16645.845870844638 19276.54413946005 22750.250483980464 18310.897261876955 23099.084899108704 19043.545515065205 21200.14399661682 23654.01192782921 0.912977805560223 0.8520004218554483 0.7037218853881025 0.8149376181205429 0.96179246689288 0.7741138085896532 0.9765398347471184 0.8050873388061608 0.8962599689769586 1.0 14.529797277596533 -10.59334290331291 0.24926858359684698 1.101755415200203 0.8235063205507449 0.2511189770996466 0.07913592251130805 23.770510145848 1.3500504315273187 1.7867839768911822 0.13583705764002577 2.550686576947483e-11 10.59334290331291 -0.278249094649458 TISAQDT(ph)LAYATALLNEK ddPTM_PC-9_Lapatinib_30min_R1 1 TISAQDTLAYATALLNEK 18 0 Q9UPU5;A0A0U1RQI9 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 T(0.005)IS(0.131)AQDT(0.856)LAY(0.008)ATALLNEK 157.88 2.6878000000000003e-05 29673000.0 96119.0 152380.0 116470.0 129430.0 168510.0 158830.0 165550.0 177990.0 174880.0 123590.0 True False 94748.32543393398 152027.1734721995 106894.28618720145 138948.71396582277 158598.57310340696 152037.2111508139 174121.36895762896 186260.06518444087 155183.17283195967 144952.36682667644 0.6536514546687408 1.048807803559238 0.7374442275579943 0.9585818914703724 1.0941426937377825 1.0488770516773211 1.201231637464952 1.2849742937082027 1.070580468806808 1.0 17.145219364795288 -6.214708091329395 1.5012879941490753 1.1488140295154852 0.8283650062926193 0.5477647126906324 0.12215588644373965 0.29458196713209156 1.3265644354545634 0.04340823077283764 0.06204150833695253 6.099467318644027e-07 6.214708091329395 -0.32044902322286584 TISDGT(ph)ISASK ddPTM_PC-9_AZD4547_30min_R2 1 TISDGTISASK 11 0 A0A075B6Q2;S4R347;Q5T0N5-3;Q5T0N5-4;Q5T0N5-2;Q5T0N5-5;Q5T0N5 A0A075B6Q2 FNBP1L Formin-binding protein 1-like 1 T(0.093)IS(0.33)DGT(0.52)IS(0.057)ASK 126.34 0.0010157999999999999 14359000.0 17096.0 24922.0 30968.0 43759.0 52412.0 42822.0 40759.0 40993.0 34380.0 31763.0 True False 22532.17238110947 32977.549123727506 30557.344085868262 33671.038619810584 45135.49849697406 40144.33357057075 44386.47203935447 34658.47377542802 36197.25661183892 30650.987037904768 0.7351206130244646 1.0759049645920236 0.9969448634094328 1.0985303206768202 1.4725626434527839 1.3097240072864853 1.4481253730740746 1.1307457646491894 1.1809491344300045 1.0 14.90364591257683 -5.07932554465584 0.9550501055881612 1.2661584635541476 0.6735692082353232 0.4843644022753465 0.15159632328289713 1.1747750736726945 1.1698877469479962 0.05485332205278306 0.6521592204805476 8.330564961399715e-06 5.07932554465584 -0.5925892553188244 TISDGT(ph)ISASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TISDGTISASK 11 0 A0A075B6Q2;S4R347;Q5T0N5-3;Q5T0N5-4;Q5T0N5-2;Q5T0N5-5;Q5T0N5 A0A075B6Q2 FNBP1L Formin-binding protein 1-like 1 TIS(0.355)DGT(0.644)ISASK 158.06 0.0022898000000000003 20239000.0 34955.0 31311.0 49840.0 67905.0 73010.0 67695.0 77251.0 65639.0 69223.0 56358.0 True False 40872.19110728019 34419.349152809904 51028.37461925256 64100.503000980374 58704.21460667028 64144.95502976329 69933.22603119326 63916.04580026923 70235.25541795029 66575.25927031749 0.6139246253826158 0.5169991004174089 0.7664765436670782 0.9628276885969187 0.8817722266512222 0.9634953845138422 1.0504386584097454 0.9600570317082661 1.0549753194767446 1.0 16.02269852141978 -5.560617701675529 2.210915930423607 0.9829532955153105 0.5597074216825623 0.9087956333302238 0.053145149334176314 0.08417099085023391 0.8176093271173523 0.01578920486367163 0.03699129083853433 2.750314119003272e-06 5.560617701675529 -0.42324587383274825 TISINS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 TISINSPK 8 0 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 T(0.093)IS(0.025)INS(0.881)PK;TIS(0.001)INS(0.999)PK;TIS(0.001)INS(0.999)PK 91.70100000000001 0.0085275 69993000.0 426474.0 390025.0 412307.0 463650.0 473431.0 397912.0 410173.0 410472.0 423284.0 417248.0 True False 562083.860789732 516092.9538954259 406839.5397833916 356762.6558210918 407703.2776639116 373030.499736887 446677.6023896114 347042.98410820164 445657.9280885876 402640.2745204064 1.3959951260693986 1.2817718111039822 1.0104293224714964 0.8860580483312047 1.012574507479501 0.9264609711018397 1.1093713934147766 0.8619182085586746 1.1068389237003686 1.0 18.619131961015036 -5.185840757284465 2.998675232312669 0.9809803779822655 1.3782651193127051 0.7685028418036771 0.07792870993879947 0.110438376483372 1.8963817171675723 0.019280274671704612 0.06525094627666886 6.518673703908943e-06 5.185840757284465 0.3972847413304397 TISINS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TISINSPK 8 0 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 TIS(0.002)INS(0.998)PK;T(0.405)IS(0.001)INS(0.594)PK;TIS(0.01)INS(0.99)PK 80.706 0.018919 51482000.0 357073.0 351593.0 282500.0 416125.0 431747.0 362022.0 405997.0 372826.0 309096.0 299908.0 True False 417518.40638678 386496.82944281265 289235.871387216 392810.8653454519 347149.2746717724 343036.92901669233 367538.02499626344 363039.71254179976 313615.9442478192 354278.9463295779 1.1785018859076426 1.0909393105264098 0.8164071683733253 1.108761526517663 0.9798755423327556 0.9682678933384109 1.0374255337610463 1.0247284415373414 0.8852232047570482 1.0 18.43452620766496 -5.009269841274949 23.301128683456064 0.9829491048357262 1.1566114910199892 0.4201944426502755 0.07669643736970624 157.62027178910103 396222.95603841916 0.01835555639535997 0.058573394415067634 9.788815854790066e-06 5.009269841274949 0.173662386184263 TISINS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 TISINSPK 8 0 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 TIS(0.001)INS(0.999)PK;T(0.032)IS(0.001)INS(0.967)PK 111.5 0.0037450000000000005 66856000.0 553550.0 456290.0 404980.0 440070.0 455390.0 366810.0 357490.0 373480.0 339140.0 345530.0 True False 545656.2754913638 455233.4885393749 371684.107668008 472434.21583048534 428604.85553118744 351122.3913758733 375999.0829879956 390833.2442557729 300942.48189747747 405254.40011021466 1.3464536729100656 1.1233276885224879 0.9171624233245174 1.165771958804149 1.0576192520417356 0.866424624335678 0.9278099951184672 0.9644145607042892 0.7426013926452912 1.0 18.628468324541686 -1.5228787452830455 0.4143533292761171 0.9044267011608409 8.242018743973004 0.5998359573837306 0.10243804057375092 55.63181018076422 0.7202464726555021 0.07255718322072828 336.9383722383614 0.029999999999812947 1.5228787452830455 7.3375920428121635 TISS(ph)GMTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TISSGMTR 8 0 H0YAZ7 H0YAZ7 STPG2 1 T(0.015)IS(0.051)S(0.934)GMTR 76.17 0.022311 16098000.0 46098.0 35203.0 42395.0 31537.0 88904.0 55723.0 41723.0 40824.0 41352.0 47169.0 True False 53901.4809229982 38697.72119147797 43405.85758393281 29770.084134333516 71483.89940270393 52800.787785264845 37770.69539163866 39752.41325660346 41956.69476970196 55720.366310401456 0.9673569018324325 0.6944986860980878 0.7789944764923438 0.5342765330811593 1.2829043334799444 0.947603027071421 0.6778615772414245 0.713426990683347 0.7529867003381454 1.0 15.765917121919026 -4.720914089240875 23.06989624527653 0.8150851540757091 0.9673609432856911 0.04604048033128294 0.19958138940750392 11845.11069137116 6741908.475368481 0.051148273413159105 15.227940394742056 1.9014543824069447e-05 4.720914089240875 0.15227578920998197 TISVLAS(ph)PSVPLLQHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TISVLASPSVPLLQHR 16 0 A0A1B0GTU4;A0A1B0GV30 A0A1B0GTU4 1 T(0.004)IS(0.001)VLAS(0.975)PS(0.02)VPLLQHR 82.865 0.013968000000000001 0.0 8616.3 7603.3 7632.1 9276.7 13155.0 7390.3 9535.8 9511.4 7357.4 7374.8 True False 10074.869410317795 8358.105375540854 7814.078208900436 8756.956574467185 10577.37218395765 7002.739658120396 8632.499990786568 9261.735828161329 7464.988056166697 8711.792861115326 1.1564633791152792 0.9594012976188703 0.8969540866585802 1.0051842042243044 1.2141441322795046 0.8038230212493679 0.99089821445564 1.0631262675563198 0.8568830980229474 1.0 13.088753936398911 -6.778590362145414 24.999993450437376 0.9498886116028181 1.030999030412381 0.1742981532450778 0.10956508911503765 583.5612911090751 850617.7896890609 0.03943136136013016 0.03485629428893839 1.6649823646411208e-07 6.778590362145414 0.08111041880956293 TITGNSAAVIT(ph)PFK ddPTM_PC-9_AZD4547_30min_R2 2 TITGNSAAVITPFK 14 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 TITGNS(0.002)AAVIT(0.998)PFK;TITGNSAAVIT(1)PFK 142.54 0.00010211 27720000.0 78658.0 100609.0 95220.0 89792.0 83411.0 103815.0 95840.0 139798.0 101818.0 107276.0 True False 103669.60781196221 133128.89173377323 93957.32058435734 69091.841672571 71830.82242866328 97323.43163861553 104369.57433331867 118195.43133845527 107199.89161443312 103520.29989227302 1.0014423057105184 1.2860172533533227 0.9076221831093296 0.667423121305391 0.693881514093497 0.940138617642084 1.0082039410814057 1.1417609054596414 1.0355446393218453 1.0 16.65955417628934 -7.36134952567141 3.409775355616414 1.066620525881951 0.9107165498527265 0.13548351473679865 0.16359022831640743 0.5698428830561256 12.466676205495814 0.08616896692215173 0.05550767103779838 4.351615092496802e-08 7.36134952567141 -0.15590397602922446 TITGNSAAVIT(ph)PFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TITGNSAAVITPFK 14 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 TITGNSAAVIT(1)PFK;TITGNS(0.015)AAVIT(0.985)PFK 133.28 2.6026999999999997e-05 17285200.0 75681.0 91332.0 66285.0 83153.0 89702.0 57920.0 69989.0 58194.0 51683.0 45263.0 True False 88492.29853211493 100398.83736783969 67865.48578726221 78494.20699566338 72125.53703119505 54882.57323766735 63359.13524352035 56666.46916163973 52438.76610037013 53468.823598289164 1.6550260988900158 1.877707991522973 1.269253393288303 1.4680369178381354 1.3489269480300077 1.0264406348267483 1.1849734289936322 1.0598039258797698 0.980735362616955 1.0 15.706410314980863 -5.534750242303719 0.45888991120032085 0.9847995412284799 2.0326857926376984 0.7979998043133267 0.12927982833892188 1.0818184956073733 0.29103551441652636 0.09932907830800351 0.5757499947462573 2.919105274811849e-06 5.534750242303719 1.0478862514092184 TITGNSAAVIT(ph)PFK ddPTM_PC-9_Lapatinib_30min_R1 2 TITGNSAAVITPFK 14 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 TITGNSAAVIT(1)PFK;TITGNS(0.009)AAVIT(0.991)PFK 148.7 3.3805e-05 24067000.0 81897.0 123006.0 121126.0 94059.0 106302.0 96458.0 106436.0 86192.0 84037.0 72054.0 True False 80729.13376192954 122721.18716446587 111167.48783988139 100976.41263162607 100049.52535777324 92332.7161945803 111946.73528465217 90196.79497936567 74571.8681111584 84508.43789408017 0.9552789730075537 1.4521767319646848 1.3154602145079846 1.19486781613673 1.1838998311999531 1.0925857641612875 1.3246811569865031 1.067311113860785 0.882419199425081 1.0 16.366807776567846 -7.979485153739784 5.187634702704485 0.9487688763598382 1.2224159380692807 0.4236380407614778 0.13026500877758654 0.15882218802408304 12.09242407410409 0.07734190610875757 0.03379592414331401 1.0483706312851724e-08 7.979485153739784 0.27364706170944253 TITLEVEPSDTIENVK ddPTM_PC-9_Lapatinib_30min_R1 2 TITLEVEPSDTIENVK 16 0 P62987;P0CG48;Q96C32;Q5PY61;J3QKN0;F5GXK7;F5H747;F5H388;B4DV12;F5H265;F5H2Z3;F5GYU3;F5H6Q2;J3QTR3;J3QS39;P0CG47;Q49A90;M0R1V7;F5GZ39;J3QSA3;P62979 P62987;P62979 UBA52;UBC;UBB;RPS27A Ubiquitin-60S ribosomal protein L40;Ubiquitin;60S ribosomal protein L40;Polyubiquitin-C;Ubiquitin;Polyubiquitin-B;Ubiquitin;Ubiquitin-40S ribosomal protein S27a;Ubiquitin;40S ribosomal protein S27a 0 ; 319.37 8.178099999999998e-147 27113000.0 90961.0 82931.0 96310.0 79164.0 82926.0 78116.0 85036.0 71575.0 74834.0 85068.0 False True 89663.87945979541 82738.97836476537 88391.7635673511 84985.9846433626 78048.45571878889 74775.16077729 89438.74799565652 74900.63579738383 66405.40688304478 99771.89045401497 0.8986887895155364 0.8292814538068706 0.8859385460686545 0.8518028901390094 0.7822689874234823 0.7494612003142709 0.8964323276692747 0.7507188192640858 0.6655723027885408 1.0 16.60634579015415 -6.1485990819732725 4.681882378180481 0.796671705197307 0.8671926796878393 0.09376437805621152 0.08709966518158402 0.4969220807430773 17.142412372401825 0.025261542043313556 0.033095192193051313 7.102331156146541e-07 6.1485990819732725 0.0705209744905323 TITLVKS(ph)PISVPGGSALISNLGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TITLVKSPISVPGGSALISNLGK 23 1 P51610;A6NEM2;P51610-2;P51610-4 P51610 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 T(0.012)IT(0.037)LVKS(0.794)PIS(0.132)VPGGS(0.022)ALIS(0.003)NLGK;T(0.016)IT(0.046)LVKS(0.82)PIS(0.118)VPGGSALISNLGK 72.23100000000001 0.00034135 15838700.0 43530.0 35000.0 40427.0 67463.0 75234.0 75774.0 65576.0 80284.0 65371.0 51624.0 True False 50898.76924331015 38474.56869305827 41390.93300025126 63683.266827997024 60492.43777178795 71800.27804749671 59364.16655087348 78176.63006792952 66326.92720521826 60983.02254464088 0.83463834882981 0.6309062274650958 0.678728788327148 1.0442786233066672 0.9919553877065733 1.1773814260343913 0.9734539888936734 1.2819408879037204 1.08762938335281 1.0 15.896120036983016 -5.805764365669342 4.996991705756706 1.0909073615206288 0.7048845138029173 0.7366767313209209 0.09992716149333596 0.0902246344230552 5.031385705622652 0.02797613030567121 0.04365662126726748 1.5639959868044473e-06 5.805764365669342 -0.38602284771771156 TITTLYVGGLGDT(ph)IT(ph)ET(ph)DLR ddPTM_PC-9_Lapatinib_30min_R1 1 TITTLYVGGLGDTITETDLR 20 0 Q9NW64-2;Q9NW64 Q9NW64-2 RBM22 Pre-mRNA-splicing factor RBM22 3 T(0.001)IT(0.001)T(0.001)LY(0.001)VGGLGDT(0.999)IT(0.999)ET(0.999)DLR 46.839 0.032462 8498100.0 22977.0 45804.0 34268.0 33627.0 49699.0 49549.0 34793.0 38204.0 49746.0 37035.0 True False 22649.343766534257 45697.94365218939 31450.617318305325 36100.04175638355 46775.8025319934 47429.90477436044 36594.41129654352 39979.09731055893 44143.08163139674 43436.45040396443 0.5214363410428919 1.0520644119672022 0.7240604843584281 0.8311001801631727 1.0768790289485577 1.0919378617096098 0.8424816244470004 0.9204043364213308 1.0162681623581242 1.0 15.406618591489293 -4.752159427266767 24.99950780436489 0.9422641187844577 0.5214355194421577 0.5561257882441353 0.11480167273998755 301.26634760617037 811531.166740255 0.029856526698132047 0.3665010295261046 1.7694592796927814e-05 4.752159427266767 -0.4208285993423 TITVPVS(ph)GSPK ddPTM_PC-9_AZD4547_30min_R2 2 TITVPVSGSPK 11 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;Q7Z589-2 E9PMC9 C11orf30;EMSY Protein EMSY 1 TIT(0.002)VPVS(0.633)GS(0.365)PK;TITVPVS(0.746)GS(0.254)PK 146.07 9.900200000000001e-05 17039700.0 184510.0 155942.0 152511.0 174192.0 163347.0 131314.0 169513.0 148793.0 151432.0 159458.0 True False 243180.34195358586 206347.20188798313 150488.60449108295 134034.7256395722 140669.0886244606 123102.91482149196 184599.3286098065 125800.4607729922 159436.38636544472 153875.42395523755 1.5803715479888922 1.341001679046614 0.9779898610375896 0.8710599925207223 0.914175149017827 0.8000167385878505 1.1996673923933854 0.8175474519543006 1.0361393799429912 1.0 17.231403306043546 -5.096214502731533 2.3554216950480242 0.94050814593207 1.5831528032703857 0.7834268571922369 0.11043236820061943 0.14440230202843005 1.4097549070014428 0.02893186157841401 0.1426774160415083 8.012822037081667e-06 5.096214502731533 0.6426446573383157 TITVPVS(ph)GSPK ddPTM_PC-9_Lapatinib_30min_R1 1 TITVPVSGSPK 11 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;Q7Z589-2 E9PMC9 C11orf30;EMSY Protein EMSY 1 TITVPVS(0.835)GS(0.164)PK 134.08 5.8033999999999994e-05 7064100.0 95957.0 85154.0 64631.0 75674.0 68428.0 63665.0 68644.0 56703.0 60275.0 56215.0 True False 94588.63558364158 84956.83114484615 59317.288662874744 81239.31840106356 64403.19957462417 60942.19636036363 72198.05044232843 59337.62838447867 53486.19477611141 65931.68784822093 1.4346460506424592 1.2885584142851363 0.8996779939780555 1.2321741040223602 0.9768170916977669 0.9243233162884676 1.0950432606629619 0.8999864908824688 0.8112365468216155 1.0 16.008684394309622 -1.5228787452946364 0.48800662667856587 0.9402306554050284 16.008061523676236 0.6473314976210457 0.11352619961569893 63.53896466404618 0.6973735060516403 0.06408084078845976 975.4043290147421 0.02999999999901227 1.5228787452946364 15.067830868271209 TITVPVSGS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TITVPVSGSPK 11 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;Q7Z589-2 E9PMC9 C11orf30;EMSY Protein EMSY 1 TIT(0.001)VPVS(0.316)GS(0.682)PK 89.189 0.0094184 3307300.0 49352.0 51908.0 39901.0 52660.0 53783.0 49794.0 59940.0 54569.0 48164.0 36788.0 True False 57706.31885356868 57061.083191979036 40852.39116538518 49709.63092602352 43244.60723449594 47182.71498267277 54262.04927198 53136.62157063475 48868.30738266407 43457.37318635224 1.3278832709495498 1.3130357177202563 0.9400566157140591 1.1438710460676165 0.9951040310019676 1.085724044579171 1.2486269945331385 1.2227297159167059 1.1245113038265997 1.0 15.407313351915953 -5.149096764783371 9.173237937200634 1.1064523451206003 1.3235005952452286 0.47896039098925103 0.09346474340096293 0.31515607153648795 23.69456714148551 0.024980365943711006 0.0664841220334787 7.094196851574716e-06 5.149096764783371 0.21704825012462825 TITVPVSGS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 TITVPVSGSPK 11 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;Q7Z589-2 E9PMC9 C11orf30;EMSY Protein EMSY 1 T(0.002)ITVPVS(0.169)GS(0.828)PK 117.2 0.0011857 7098900.0 86626.0 77896.0 60741.0 65440.0 67106.0 58726.0 64144.0 63407.0 60195.0 52454.0 True False 85390.69735473717 77715.63659791605 55747.10944704053 70252.67590144045 63158.95701547209 56214.42587699228 67465.06246099756 66353.12069863391 53415.2052185488 61520.60400943837 1.388001609048518 1.2632456694669816 0.9061534805231742 1.1419373563150066 1.0266309642503244 0.913749576781918 1.096625489090569 1.078551190564614 0.8682490375152029 1.0 15.90878204730211 -5.089674540549255 4.287652163558358 1.0133055463818794 1.3653540413347403 0.7032446149070581 0.0849432846173083 0.11050238715347999 3.5104646686755263 0.021408072768024092 0.06680010112652938 8.134398780908127e-06 5.089674540549255 0.35204849495286084 TIVFVETK ddPTM_PC-9_Lapatinib_30min_R1 2 TIVFVETK 8 0 P17844-2;P17844;J3KTA4;J3QSF1 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 ; 112.84 0.017156 12876900.0 158486.0 117460.0 136425.0 124021.0 128991.0 130822.0 137377.0 112288.0 132186.0 131375.0 False True 156225.96057722738 117188.02858672115 125208.6631157289 133141.91806192792 121404.00298606353 125227.04802097689 144489.70886917654 117505.3104074974 117297.8206997109 154082.99370381638 1.0139078740742167 0.7605513481389387 0.8126053375910471 0.8640922327733188 0.7879130594998074 0.8127246557896753 0.9377394960726141 0.7626105099786037 0.7612638999290525 1.0 17.23334811336226 -12.009034123083508 2.1910252217508117 2.9555095846750383 0.8317194687503474 0.2799604362581556 0.07932903367447897 5432629.812146567 447089.0460074679 52741570.78342857 0.018964538414756153 9.794130286272036e-13 12.009034123083508 -2.123790115924691 TIVLVPS(ph)PLGQQQDMIFEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TIVLVPSPLGQQQDMIFEAR 20 0 Q96R06;F5GZT2 Q96R06 SPAG5 Sperm-associated antigen 5 1 T(0.003)IVLVPS(0.997)PLGQQQDMIFEAR;TIVLVPS(1)PLGQQQDMIFEAR 67.234 0.004958 8127600.0 41830.0 39523.0 57048.0 59709.0 63510.0 69296.0 74453.0 65333.0 65826.0 52957.0 True False 48910.992819840685 43446.58224159259 58408.240675744804 56363.69830918987 51065.67141034971 65661.99577136397 67400.27284695907 63618.07797603549 66788.58071944272 62557.68489261869 0.78185426624718 0.6945043173539649 0.9336701122492549 0.9009875989806705 0.8162973341805213 1.0496231739405621 1.077409961104743 1.0169506445968548 1.0676319117960718 1.0 15.932899502556928 -5.976345440384381 0.6118301215056545 1.0567128136496524 0.7120480845398307 0.7029830351502079 0.06860841805400807 0.64664596395051 0.44836357241915353 0.0459034419593735 0.13159158262196138 1.0559772445731914e-06 5.976345440384381 -0.3446647291098217 TIYISGQIGMDPS(ph)SGQLVSGGVAEEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TIYISGQIGMDPSSGQLVSGGVAEEAK 27 0 H0YB34;P52758 H0YB34 HRSP12 Ribonuclease UK114 1 T(0.001)IYIS(0.015)GQIGMDPS(0.488)S(0.488)GQLVS(0.008)GGVAEEAK 42.355 0.043531 2123400.0 5169.4 8362.6 6370.5 8230.9 9194.6 7412.1 7531.4 7716.5 7200.3 6281.9 True False 6044.477319696017 9192.783661501971 6522.396880255788 7769.749357937846 7392.9841339883715 7023.396427743687 6817.971269385887 7513.950051307579 7305.590765870697 7420.758742506963 0.814536293313587 1.2387929564189502 0.878939351968788 1.0470289666515937 0.9962571740326908 0.9464526029545821 0.91877010235244 1.0125581914241202 0.9844802963372774 1.0 12.857350988770868 -6.554969849947453 13.18398636736829 0.970037438851795 1.0061807678487962 0.006406393944962785 0.10714193429132453 6.435440723475299 2634.8798420700887 0.03304353539441698 0.0330668848809766 2.786314596405238e-07 6.554969849947453 0.03614332899700112 TKADVTPPPDGSTTHNLEVS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 TKADVTPPPDGSTTHNLEVSPK 22 1 O75362 O75362 ZNF217 Zinc finger protein 217 1 TKADVTPPPDGS(0.014)T(0.049)T(0.101)HNLEVS(0.837)PK 55.852 0.0053256 4727700.0 33000.0 18095.0 20370.0 20149.0 25525.0 19663.0 17245.0 18403.0 27187.0 19533.0 True False 32529.413948541183 18053.10213925349 18695.257230473897 21630.824675093616 24023.669684080825 18822.059326691753 18137.86171956695 19258.070563454497 24124.913768198126 22909.253023913523 1.419924687836211 0.7880266598133512 0.8160570408366915 0.9441959828421539 1.0486448274417344 0.8215920138052775 0.7917264565821497 0.8406241156510958 1.0530641807926104 1.0 14.483642798634445 -4.754427305332372 24.999623867689188 0.8929573138720467 1.41992559668556 0.7100815587066189 0.09947863043794201 135.90700920143556 484497.05182870914 0.02545949439999236 0.24859888450644269 1.7602432786231046e-05 4.754427305332372 0.5269682828135133 TKDGVVEITGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TKDGVVEITGK 11 1 P04792 P04792 HSPB1 Heat shock protein beta-1 0 ; 92.24700000000001 0.018853 4784400.0 94444.0 93930.0 109658.0 115300.0 129188.0 94970.0 117946.0 103275.0 89022.0 92172.0 False True 110431.50384597263 103254.74963825589 112272.66260028076 108840.11480764355 103874.53878381767 89989.6060148699 106773.30102490727 100564.14067890738 90323.77833692226 108882.05396684933 1.014230534993352 0.9483174304343418 1.0311401972125154 0.9996148202786609 0.9540097288708728 0.8264870356162505 0.9806326858732468 0.9236062052018742 0.8295561577523382 1.0 16.732406661856437 -6.524613986429382 24.989811021712203 0.909198992100394 0.9945619536124971 0.34945793137505055 0.055342859181083955 62.99984004644098 907259.8195192215 0.01759302992567784 0.01771323892077222 2.988037293445786e-07 6.524613986429382 0.0853629615121031 TKDQPDGSSLS(ph)PAQSPSQSQPPAASSLR ddPTM_PC-9_AZD4547_30min_R2 2 TKDQPDGSSLSPAQSPSQSQPPAASSLR 28 1 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 TKDQPDGSSLS(1)PAQSPSQSQPPAASSLR;TKDQPDGS(0.007)S(0.094)LS(0.898)PAQS(0.001)PSQSQPPAASSLR 138.93 2.3068999999999998e-10 29237000.0 40282.0 48907.0 47589.0 44078.0 44952.0 55725.0 55784.0 53264.0 51825.0 41580.0 True False 53090.838082349794 64715.23132148869 46957.938765899766 33916.49809831146 38711.19072800084 52240.50694082607 60748.66793207267 45033.272684955926 54564.36369716558 40124.296855967 1.3231593384160327 1.6128689196422568 1.1703118171631341 0.8452857932952822 0.964781784636906 1.3019669136720893 1.5140120249369196 1.1223442206753313 1.3598833617703923 1.0 15.292188490007497 -1.5228791787479545 0.017692181721256927 2.214521854603099e-10 2.747499719364108 0.06863217546655642 0.22501919207258333 15848.098787031746 21.708924412295676 1294.9060875016523 2183.23309342024 0.02999997005713275 1.5228791787479545 2.747499719142656 TKDQPDGSSLS(ph)PAQSPSQSQPPAASSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TKDQPDGSSLSPAQSPSQSQPPAASSLR 28 1 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 TKDQPDGS(0.001)S(0.008)LS(0.99)PAQSPSQSQPPAASSLR;TKDQPDGSS(0.003)LS(0.997)PAQSPSQSQPPAASSLR 113.02 1.4489000000000001e-11 21971000.0 39269.0 62196.0 49640.0 42575.0 54360.0 36719.0 43781.0 31160.0 33973.0 31825.0 True False 45916.46610189633 68370.40784095562 50823.60586074832 40189.660780012375 43708.54822652513 34793.390999894815 39633.746733008964 30342.083016749035 34469.79085439845 37594.62057343862 1.2213573485121771 1.8186221006646026 1.3518850592325504 1.0690269024395265 1.162627725983917 0.9254885531276533 1.0542398387978686 0.8070857626419655 0.9168809347886351 1.0 15.19823862051488 -5.750183682160171 2.203807108814369 0.9731005009465296 1.535776569322515 0.6527395355026127 0.16145264147903765 0.1725128960253479 1.708444658320843 0.04734585857872324 0.09103736545655973 1.7775274568091068e-06 5.750183682160171 0.5626760683759854 TKDQPDGSSLS(ph)PAQSPSQSQPPAASSLR ddPTM_PC-9_Lapatinib_30min_R1 2 TKDQPDGSSLSPAQSPSQSQPPAASSLR 28 1 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 TKDQPDGSS(0.003)LS(0.996)PAQSPSQSQPPAASSLR;TKDQPDGSSLS(0.999)PAQSPSQSQPPAASSLR 130.44 1.9436e-12 29147000.0 28366.0 45983.0 39488.0 37336.0 47690.0 40665.0 44040.0 45411.0 42505.0 37368.0 True False 27961.495638312685 45876.52918868709 36241.449068088026 40081.81398924488 44884.96796214749 38925.85274474493 46320.17571062502 47520.96084100592 37717.63930250713 43827.00901026985 0.6379968943753508 1.046763861479504 0.8269204284416415 0.914545959087754 1.0241394285343481 0.8881704141759605 1.0568865354186263 1.0842848260503124 0.8606026318991759 1.0 15.419532604538187 -4.752658636142441 24.9947561441691 0.9656840589951152 0.6379962707927114 0.5732665711081002 0.08513139189826907 250.35997086430626 712607.2146560253 0.021103163978575652 0.2457674952879249 1.7674265062455573e-05 4.752658636142441 -0.32768778820240385 TKDQPDGSSLS(ph)PAQSPSQSQPPAASSLREPGLESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESK 35 2 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 T(0.003)KDQPDGS(0.005)S(0.023)LS(0.903)PAQS(0.056)PS(0.007)QS(0.003)QPPAASSLREPGLESK 64.396 7.4115999999999995e-06 11470000.0 15684.0 14399.0 18608.0 22583.0 19670.0 21712.0 17249.0 17145.0 15295.0 21371.0 True False 18338.991426879773 15828.437560324155 19051.685291232978 21317.747725073838 15815.804702276464 20573.384498208463 15615.049848054445 16694.961916629098 15518.66043970283 25245.393127257095 0.7264292274806932 0.6269832076108339 0.7546598777526321 0.8444213016456205 0.6264828051023837 0.8149361903180533 0.6185306669356277 0.6613072663385773 0.6147125680109751 1.0 14.623732523103183 -11.831927398661028 2.3755184359052883 2.624706782678638 0.700373842890938 0.5610002297570633 0.07994278672898959 10126131.675956685 1143723.5923975736 88762518.24817571 0.021165808290157424 1.4725586506077725e-12 11.831927398661028 -1.9243329397877003 TKDQPDGSSLS(ph)PAQSPSQSQPPAASSLREPGLESK ddPTM_PC-9_Lapatinib_30min_R1 1 TKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESK 35 2 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 T(0.002)KDQPDGS(0.008)S(0.017)LS(0.894)PAQS(0.044)PS(0.014)QS(0.011)QPPAAS(0.004)S(0.004)LREPGLES(0.002)K 51.729 0.0011394999999999999 11438000.0 30938.0 25200.0 23844.0 22830.0 24880.0 27040.0 19691.0 17768.0 25272.0 20726.0 True False 30496.818446665642 25141.650948283386 21883.638360501693 24508.99435864742 23416.607315962025 25883.562233318666 20710.50363119703 18593.56614527303 22425.601234042108 24308.46148434094 1.2545762497684654 1.0342756971468217 0.9002477748169594 1.0082495091034724 0.9633109578344384 1.0647963981592325 0.8519874301604136 0.7649009854963739 0.9225430103212523 1.0 14.569170965670052 -1.5228799722080588 0.8924580926033399 0.9222463455124784 159.19296756948057 0.5843777445564586 0.08134267893833641 647.9879385017206 1.4767331814628866 0.029478434206765613 208792.55838554996 0.029999915246955285 1.5228799722080588 158.27072122396808 TKDS(ph)GSISLQETR ddPTM_PC-9_AZD4547_30min_R2 2 TKDSGSISLQETR 13 1 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 T(0.023)KDS(0.863)GS(0.109)IS(0.005)LQETR;T(0.008)KDS(0.494)GS(0.494)IS(0.003)LQETR 95.195 0.006606600000000001 73579000.0 67826.0 55538.0 72600.0 116592.0 112815.0 93932.0 98876.0 124279.0 87829.0 105147.0 True False 89393.25713155902 73489.57239521616 71637.27656400263 89713.51572844347 97152.58457864853 88058.41719094972 107675.77245180742 105074.53619731248 92471.46163354281 101465.83553425579 0.8810182921263092 0.7242789852196645 0.7060236205300575 0.8841746116421164 0.9574906082141208 0.8678627316011249 1.061202244921692 1.0355656723670141 0.9113556414988926 1.0 16.630634515124278 -6.026370785016033 2.942861147059978 0.9735459854196827 0.7663651133171214 0.6304134774998569 0.068743229039505 0.1693958960028893 2.9608114431226 0.021684625433549123 0.03155904002357925 9.410857882258143e-07 6.026370785016033 -0.2071808721025613 TKDS(ph)GSISLQETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TKDSGSISLQETR 13 1 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 T(0.007)KDS(0.496)GS(0.496)IS(0.001)LQETR;T(0.052)KDS(0.473)GS(0.473)IS(0.002)LQETR 141.82 0.00038042 36198000.0 22873.9 20396.3 19407.3 23176.2 27095.3 28085.9 23569.7 25006.4 18816.3 17234.8 True False 26745.99948988176 22421.109869549266 19870.043634595106 21877.712652254184 21786.170470238518 26613.025961598803 21337.007386149264 24350.008496470895 19091.452790557727 20359.33280939827 1.3136972483467277 1.1012693824229465 0.9759673276436004 1.0745790570384015 1.0700827317966721 1.3071659179967678 1.0480209536286806 1.1960121053294266 0.9377248738595567 1.0 14.31340266353948 -8.269773967312913 24.666582863005935 0.9688624112141702 1.1279156520008957 0.2869913154944387 0.10468648971538565 780.9534264848429 2311231.7189366086 0.0956987751526608 0.02636056293815269 5.3731137241592146e-09 8.269773967312913 0.15905324078672556 TKDS(ph)GSISLQETR ddPTM_PC-9_Lapatinib_30min_R1 2 TKDSGSISLQETR 13 1 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 T(0.002)KDS(0.814)GS(0.183)IS(0.001)LQETR;TKDS(0.347)GS(0.347)IS(0.306)LQET(0.001)R 188.63 0.00013212 36576000.0 49211.0 37199.0 39238.0 34689.0 38005.0 37060.0 23073.0 22005.2 39367.0 23089.0 True False 48509.24211580785 37112.86800099975 36012.003103060124 37240.14477911174 35769.62062070486 35475.03019107949 24267.60704294394 23027.641925932126 34933.07390711206 27079.902885841355 1.7913373737086318 1.3704948705855255 1.3298424021265192 1.3751949161746306 1.320891761373594 1.3100131983718266 0.8961482301191037 0.8503591029483366 1.2899999698808637 1.0 14.724934944667444 -1.5228787453003318 0.24902880801686497 0.960049800338968 5.647267475335954 0.6540670026363042 0.15417747786820096 32.776259011076384 0.44496226942897116 0.21162623793478613 64.26708426421241 0.029999999998618843 1.5228787453003318 4.687217674996986 TKETDSPS(ph)TPGKDQR ddPTM_PC-9_Lapatinib_30min_R1 1 TKETDSPSTPGKDQR 15 2 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 T(0.002)KET(0.003)DS(0.015)PS(0.609)T(0.371)PGKDQR 74.33800000000001 0.045265 3832500.0 21898.0 13852.0 14095.0 14813.0 11167.0 12245.0 11321.0 10787.0 13173.0 11045.0 True False 21585.730504398623 13819.92654506434 12936.163508273425 15902.397434719418 10510.179015166716 11721.309894489166 11907.145985921577 11288.203399879569 11689.318022160365 12954.113533462596 1.666322473447461 1.0668369170430079 0.998614337820739 1.2275944157538006 0.811339115410499 0.9048330373368354 0.9191787577871284 0.8713991405679973 0.9023634069567896 1.0 13.66112267298063 -1.9297060532041956 0.9424889887664503 0.9287158331445361 199.99999999990771 0.7996656633277638 0.10628938140962782 209.8195406137897 0.9076879137722338 0.03533806429040661 89307.2499979704 0.01175693038851606 1.9297060532041956 199.07128416676318 TKEVYELLDS(ph)PGK ddPTM_PC-9_AZD4547_30min_R2 2 TKEVYELLDSPGK 13 1 E9PBS1;P22234;P22234-2 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 1 TKEVYELLDS(1)PGK;TKEVYELLDS(1)PGK 98.169 0.0013338 39602000.0 331661.0 321100.0 252852.0 264477.0 263449.0 300353.0 275287.0 304736.0 293903.0 273561.0 True False 437122.2990226448 424889.2955472632 249499.01726943828 203505.91377891717 226873.65381075547 281571.87942930294 299787.00969841756 257646.0533366389 309438.1125651338 263983.71265548747 1.6558684421304137 1.6095284488318637 0.9451303444430585 0.7709032944941683 0.8594229224544524 1.066625954294267 1.1356269168380675 0.9759922335545014 1.1721863801838663 1.0 18.010089394944686 -5.257687355773399 22.690982740779617 0.9852226634222615 1.6326987963035595 0.8363808005011872 0.11355456951565503 34.22689179027599 206982.84257402676 0.03248651406181432 0.07902509380831202 5.524750173620171e-06 5.257687355773399 0.647476132881298 TKEVYELLDS(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TKEVYELLDSPGK 13 1 E9PBS1;P22234;P22234-2 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 1 TKEVYELLDS(1)PGK;TKEVYELLDS(1)PGK;TKEVYELLDS(1)PGK;TKEVYELLDS(1)PGK 108.25 0.00043295 33568500.0 265770.0 265462.0 226139.0 248959.0 267619.0 211400.0 254480.0 193808.0 193435.0 169197.0 True False 310759.61180322943 291815.3129827606 231531.01139693355 235010.634365968 215180.9780690654 200313.81185156928 230373.8121243488 188720.74535655047 196263.62093193308 199871.07673728454 1.554800308659464 1.4600177161517462 1.1584017816708096 1.175811118858742 1.0765988835488416 1.0022151034632523 1.152612053154433 0.9442123814873408 0.9819510863490609 1.0 17.60871018980739 -4.432524953078345 0.5664515556362136 1.0017256921030133 2.2344670048352846 0.9050319929714025 0.060154564649956964 1.528436267594101 0.2800945912943815 0.031364061442763665 1.3481286543169444 3.693814203531327e-05 4.432524953078345 1.2327413127322713 TKEVYELLDS(ph)PGK ddPTM_PC-9_Lapatinib_30min_R1 4 TKEVYELLDSPGK 13 1 E9PBS1;P22234;P22234-2 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 1 TKEVYELLDS(1)PGK;TKEVYELLDS(1)PGK;TKEVYELLDS(1)PGK;TKEVYELLDS(1)PGK 113.33 0.00016833 23354800.0 278658.0 333059.0 275984.0 273990.0 265906.0 254784.0 276381.0 238666.0 250398.0 204026.0 True False 274684.2858203814 332287.82234858384 253293.66084904812 294140.13860384584 250265.93187131043 243887.48225051284 290690.6558373808 249755.2936530689 222195.54043216494 239291.62225244418 1.14790598699105 1.3886312409133654 1.058514537470235 1.229212021027374 1.0458616541421946 1.0192061048974803 1.214796628068794 1.0437276963653408 0.9285554518818737 1.0 17.868410362552552 -5.750269103400388 0.3303220289851037 0.9829021026134004 1.355238683488434 0.38705500397416503 0.10166734862682618 3.8494973483896158 0.5485482205605637 0.11207493339187712 0.5466315018318473 1.7771778698936754e-06 5.750269103400388 0.37233658087503363 TKEVYELLDS(ph)PGKVLLQSK ddPTM_PC-9_AZD4547_30min_R2 1 TKEVYELLDSPGKVLLQSK 19 2 E9PBS1;P22234;P22234-2 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 1 T(0.006)KEVY(0.002)ELLDS(0.974)PGKVLLQS(0.018)K 44.998000000000005 0.030607 4838900.0 17394.0 8794.9 16669.0 26897.0 21705.0 13655.0 10847.0 13388.0 9993.3 18943.0 True False 22924.930182324417 11637.679431356672 16447.95816866888 20696.312204507525 18691.635405571662 12801.150691376948 11812.361986576661 11319.192225634395 10521.525436273705 18279.811335800452 1.2541119687283995 0.6366411128415003 0.8997881797858633 1.132195066147889 1.0225289015409402 0.7002889940284168 0.6461971499368 0.6192182193623685 0.5755817301936601 1.0 14.157963560103546 -6.780591269159339 11.253886523902837 0.6804299399128746 0.9724706678560792 0.35816498290424936 0.18542752917011654 0.5476562914413305 315.93571654099964 0.06408555729711136 0.05740868629252135 1.6573290042618352e-07 6.780591269159339 0.29204072794320457 TKEVYELLDS(ph)PGKVLLQSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TKEVYELLDSPGKVLLQSK 19 2 E9PBS1;P22234;P22234-2 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 1 T(0.008)KEVY(0.004)ELLDS(0.965)PGKVLLQS(0.023)K 47.082 0.026105 1973100.0 19501.0 5902.6 5987.3 18560.0 16786.0 19871.0 14940.0 20602.0 18675.0 11856.0 True False 22802.134137693367 6488.571119075589 6130.059938961695 17520.14337233187 13496.903799309237 18828.929779103735 13524.775043766786 20061.21932962337 18948.08654537105 14005.39894795564 1.6280960094336892 0.46329070262027217 0.43769263280118814 1.2509563945616327 0.9636929193851612 1.3444051004239463 0.9656829551250298 1.4323918514689433 1.3529130170288288 1.0 13.773695459144632 -5.7993790923545765 24.999812645504896 1.1931793613922832 0.805051966872856 0.17142684564005828 0.34348760955917756 244.7851882018156 161296.54152996492 0.09580901759995299 0.1421110951367697 1.5871607232202275e-06 5.7993790923545765 -0.38812739451942724 TKEVYELLDS(ph)PGKVLLQSK ddPTM_PC-9_Lapatinib_30min_R1 1 TKEVYELLDSPGKVLLQSK 19 2 E9PBS1;P22234;P22234-2 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 1 TKEVYELLDS(0.921)PGKVLLQS(0.078)K 57.93600000000001 0.008096800000000001 1022800.0 23816.0 9604.7 8444.2 8625.7 6098.1 6900.0 4770.3 5368.4 7360.8 5077.6 True False 23476.3794726805 9582.460907261007 7749.950471554628 9260.062752491682 5739.421747325883 6604.903084685604 5017.282792742839 5617.83546230773 6531.7491913397125 5955.256394523282 3.9421274110499116 1.6090761291274482 1.3013630242153513 1.5549393911918965 0.9637572871932281 1.1090879463661323 0.8424965207806929 0.9433406540605273 1.0968040263298484 1.0 12.53994790713341 -2.857307393069074 1.099665386099126 1.0499144787185286 199.99999914088417 0.9522634924284807 0.1901324937538635 22.069583996851073 0.5085708347545022 0.06129721006501594 10595.073938012752 0.0013889691726363563 2.857307393069074 198.95008466216564 up TKEYVSNDAAQS(ph)DDEEKLQSQPTDTDGGR ddPTM_PC-9_Lapatinib_30min_R1 2 TKEYVSNDAAQSDDEEKLQSQPTDTDGGR 29 2 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 TKEYVSNDAAQS(0.989)DDEEKLQS(0.009)QPT(0.002)DTDGGR;TKEYVSNDAAQS(0.95)DDEEKLQS(0.043)QPT(0.006)DT(0.001)DGGR 82.486 3.1109e-07 38522000.0 112435.0 74804.0 68531.0 71478.0 76902.0 70076.0 65197.0 58561.0 73039.0 61777.0 True False 110831.6562819464 74630.79593394407 62896.645717310064 76734.7305636179 72378.77555514914 67079.01283513458 68572.58164862888 61281.957847441125 64812.57868523269 72455.07213732178 1.5296604228326585 1.0300285919597003 0.8680778841556331 1.0590663745139197 0.9989469807989696 0.925801477472852 0.9464152008387413 0.8457925172070133 0.8945209323978794 1.0 16.144799067140163 -4.766974740415349 3.636381817188236 0.9424750592299515 1.6052006942872872 0.8904246698644634 0.06145346284402191 0.08906013139956905 1.9825122692089876 0.016314882919811168 0.16497277380134806 1.7101147764801295e-05 4.766974740415349 0.6627256350573357 TKFENLCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TKFENLCK 8 1 P07900;P07900-2;Q58FG0 P07900 HSP90AA1;HSP90AA5P Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-alpha A5 0 76.1 0.03297 7658100.0 44717.0 51435.0 44049.0 45154.0 56576.0 52226.0 55259.0 50711.0 52187.0 33353.0 False True 52286.70489899152 56541.12687792718 45099.29521676275 42624.16777124316 45490.33893421422 49487.17662138148 50024.46747948522 49379.88998274587 52950.136146895835 39399.634877797274 1.3270860265879378 1.435067280529282 1.144662770521698 1.081841694813852 1.1545878299458356 1.256031350921701 1.2696683011058896 1.2533083145542736 1.3439245391772559 1.0 15.265894639626229 -11.828602006931193 1.9871459475887947 4.624656774536372e-05 1.2468735997445546 0.36683309180715584 0.09905249141788772 1571421.2699788979 175795.05420880858 7070303.27032614 0.02791318565993153 1.4838773065634607e-12 11.828602006931193 1.2468273531768093 TKFENLCK ddPTM_PC-9_Lapatinib_30min_R1 1 TKFENLCK 8 1 P07900;P07900-2;Q58FG0 P07900 HSP90AA1;HSP90AA5P Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-alpha A5 0 74.376 0.03613 12311000.0 60193.0 58852.0 65369.0 57766.0 72393.0 60498.0 55368.0 58637.0 64415.0 62715.0 False True 59334.63678195571 58715.73180985608 59994.6131516371 62014.30434172703 68134.98607011409 57910.64156772605 58234.684122295344 61361.48908489276 57159.90437997871 73555.20418751545 0.8066680996587675 0.7982539435302379 0.8156406309292797 0.8430987994219006 0.9263108820474005 0.787308555627057 0.7917139890447008 0.8342236251355233 0.7771021100595419 1.0 16.16653979839065 -11.197491087315392 3.0664557371068866 1.0179199899661269 0.821691539115345 0.6391698421122638 0.04054778582974884 29329462.24415767 28075885.55870895 4084234.5034249076 0.010909338351433586 6.3461292451035004e-12 11.197491087315392 -0.1962284508507819 TKPIVKPQT(ph)SPEYGQGINPISR ddPTM_PC-9_AZD4547_30min_R2 1 TKPIVKPQTSPEYGQGINPISR 22 2 O95793-2;O95793-3;O95793;A0A087X1A5 O95793-2 STAU1 Double-stranded RNA-binding protein Staufen homolog 1 1 T(0.084)KPIVKPQT(0.453)S(0.453)PEY(0.007)GQGINPIS(0.002)R 48.706 0.021878 85633000.0 141210.0 124400.0 165140.0 229350.0 164570.0 131440.0 155270.0 148010.0 134350.0 134540.0 True False 186111.84264953577 164609.8672254114 162950.13569944067 176476.9009221774 141722.29618497717 123221.03602157348 169088.7292021532 125138.45543144224 141451.46671903896 129829.79555078904 1.4335063985888306 1.267889751555655 1.2551058484544486 1.3592942989203132 1.0916007037039184 0.9490967423835291 1.3023877029522561 0.9638654586226197 1.0895146689474955 1.0 16.986261989980484 -4.996910780052368 0.3376544870382923 1.0077595400071342 1.6594791588556317 0.5591357940217467 0.10959002147326795 4.646453541753192 0.4770542020919699 0.11310171252306898 1.2298551331033585 1.0071385506409653e-05 4.996910780052368 0.6517196188484975 TKPIVKPQT(ph)SPEYGQGINPISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TKPIVKPQTSPEYGQGINPISR 22 2 O95793-2;O95793-3;O95793;A0A087X1A5 O95793-2 STAU1 Double-stranded RNA-binding protein Staufen homolog 1 1 T(0.011)KPIVKPQT(0.489)S(0.489)PEY(0.008)GQGINPIS(0.002)R;TKPIVKPQT(0.492)S(0.492)PEY(0.016)GQGINPISR 71.434 0.013109 102330000.0 112002.0 104437.0 109083.0 118052.0 126414.0 130229.0 134999.0 141833.0 97475.0 104242.0 True False 130961.72645966506 114804.81515991196 111683.9524195814 111437.92916974804 101644.08417049181 123399.56198494788 122210.91741187914 138110.03403448538 98900.38747041712 123140.24942078177 1.0635168198511324 0.9323094252279216 0.9069654556078319 0.9049675446811399 0.8254334764514278 1.0021058310778632 0.9924530605283491 1.1215669505634218 0.8031524049660256 1.0 16.909942870286635 TKPLT(ph)PSIGAK ddPTM_PC-9_AZD4547_30min_R2 2 TKPLTPSIGAK 11 1 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YD28;A0A2R8YF61;A0A2R8YCQ1;A0A2R8Y7Y0 Q14004 CDK13 Cyclin-dependent kinase 13 1 T(0.004)KPLT(0.987)PS(0.009)IGAK;T(0.001)KPLT(0.98)PS(0.018)IGAK 78.69 0.013055 35522000.0 327150.0 273456.0 332046.0 409870.0 365360.0 380400.0 290700.0 353520.0 328020.0 375140.0 True False 431176.8948572739 361845.3042764635 327642.85308499803 315380.8039283753 314636.0705726635 356613.5278652351 316571.7368394794 298891.6070814367 345358.4675338979 362006.4627837288 1.1910751303765237 0.9995548187012298 0.9050745960873622 0.8712021368435935 0.8691448991081536 0.9851026556901126 0.8744919480307921 0.8256526825047364 0.9540118838713197 1.0 18.465655927940894 -4.786232503456077 2.063934033445951 0.9025587799013528 1.2719984585172033 0.7214453936250371 0.05282809762976843 0.351493937306121 1.6856187836007765 0.013858595141182714 0.24673120376270063 1.6359404715062804e-05 4.786232503456077 0.3694396786158505 TKPPRPDS(ph)PATTPNISVK ddPTM_PC-9_Lapatinib_30min_R1 1 TKPPRPDSPATTPNISVK 18 2 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 TKPPRPDS(0.952)PAT(0.038)T(0.008)PNIS(0.001)VK 69.52199999999999 0.030691000000000003 32521000.0 15738.0 15785.0 21394.0 19131.0 15964.0 18199.0 13901.0 18688.0 18992.0 15859.0 True False 15513.573234004272 15748.45080232751 19635.067903228202 20537.957559145158 15025.028906431578 17420.671193941067 14620.725761884625 19556.312703898155 16852.920965373833 18600.207019210815 0.8340537940239815 0.8466814797309551 1.055637062692289 1.1041789770368136 0.8077882622980114 0.9365848012308954 0.7860517760250695 1.0514029593165197 0.9060609351265642 1.0 14.183031058083118 TKPPRPDSPATT(ph)PNISVK ddPTM_PC-9_Lapatinib_30min_R1 1 TKPPRPDSPATTPNISVK 18 2 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 T(0.017)KPPRPDS(0.306)PAT(0.285)T(0.391)PNIS(0.001)VK 52.861999999999995 0.024628999999999998 47350000.0 80391.0 59549.0 58553.0 64525.0 62871.0 62968.0 50810.0 54033.0 61248.0 46827.0 True False 79244.60959809605 59411.11794917966 53738.99836111627 69270.38374909003 59173.051389141794 60275.00542557731 53440.69318476062 56543.57043716442 54349.60526996719 54920.98455694459 1.4428839948404715 1.0817562436008314 0.9784784230405996 1.2612735242804567 1.077421533253623 1.0974858865299733 0.9730468893788833 1.0295440056894365 0.9895963393302798 1.0 15.745069868156998 -4.76343470355943 5.325175589893554 1.0574488226286838 1.462965460937039 0.6752148323813463 0.08099704588834679 0.09545186651546202 8.047997406923269 0.02079497302164762 0.14340175970547295 1.7241112927266496e-05 4.76343470355943 0.40551663830835527 TKPTQAAGPS(ph)SPQKPPTPEETK ddPTM_PC-9_AZD4547_30min_R2 1 TKPTQAAGPSSPQKPPTPEETK 22 2 P18887;F5H8D7 P18887 XRCC1 DNA repair protein XRCC1 1 T(0.005)KPT(0.004)QAAGPS(0.495)S(0.495)PQKPPT(0.002)PEETK 71.148 0.00052629 93283000.0 244430.0 224160.0 231170.0 268030.0 297530.0 277920.0 263670.0 262910.0 247240.0 281390.0 True False 322153.6555401612 296615.3363122846 228104.53475620507 206239.82452222 256223.09524163778 260541.61846557894 287136.1192035279 222283.30057077465 260308.60164953626 271538.6217484495 1.1864008643256683 1.0923504524047627 0.8400445332138375 0.7595229849596805 0.9435972444428187 0.9595011449492512 1.0574411748673003 0.8186065729415668 0.958643009872398 1.0 18.050797885881558 -5.0863368559171285 4.315391565756554 0.9131895161625234 1.1689568988815606 0.533053655846347 0.08498838612078756 0.1626303543767389 5.292011610682359 0.02305316661223493 0.07197399892578195 8.197154940440252e-06 5.0863368559171285 0.2557673827190372 TKPTQAAGPS(ph)SPQKPPTPEETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TKPTQAAGPSSPQKPPTPEETK 22 2 P18887;F5H8D7 P18887 XRCC1 DNA repair protein XRCC1 1 T(0.001)KPT(0.001)QAAGPS(0.464)S(0.464)PQKPPT(0.052)PEET(0.018)K 48.196000000000005 0.015766 7771000.0 34089.0 36591.0 23771.0 45589.0 41443.0 38815.0 35891.0 40269.0 30884.0 27782.0 True False 39859.59441155984 40223.51265850556 24337.790792019518 43034.79613153222 33322.54165106476 36779.4730700977 32491.14465166221 39211.98141853231 31335.620073212296 32818.65667780901 1.2145407047849004 1.2256294659891882 0.7415840029941262 1.3112906038177683 1.0153536135924923 1.1206879498808637 0.9900205535722534 1.1948076304124378 0.9548111728290359 1.0 15.00222856770255 -5.1054028917070395 20.631160684700504 1.0528335267332414 1.2204283970383465 0.1955975352191417 0.1436181445270576 11.192501365472303 2175.6028180942976 0.0339762584435805 0.0898936447681802 7.84507515236868e-06 5.1054028917070395 0.16759487030510511 TKPTQAAGPS(ph)SPQKPPTPEETK ddPTM_PC-9_Lapatinib_30min_R1 2 TKPTQAAGPSSPQKPPTPEETK 22 2 P18887;F5H8D7 P18887 XRCC1 DNA repair protein XRCC1 1 T(0.004)KPT(0.013)QAAGPS(0.535)S(0.385)PQKPPT(0.06)PEET(0.003)K;TKPT(0.001)QAAGPS(0.496)S(0.496)PQKPPT(0.006)PEET(0.001)K 70.12100000000001 0.00060203 88477000.0 234432.0 173052.0 180199.0 165293.0 173985.0 163813.0 152590.0 187916.0 159122.0 158379.0 True False 231088.9566904359 172651.30872628358 165383.73380825575 177449.1986212841 163751.544367671 156807.09985675412 160490.3635713957 196647.26338108562 141200.00473105622 185754.59912324834 1.244055101629587 0.9294591334006718 0.8903345305519111 0.9552883183449278 0.8815477255506429 0.8441626780541379 0.8639913322679574 1.0586400784112484 0.7601427119302165 1.0 17.50303840552457 -4.761300201275815 4.847329599714614 0.9060853040215753 1.2676737986982638 0.6193359661699657 0.07891255677939227 0.11368124572847675 6.6510010222054925 0.018464611586050228 0.14149241563089832 1.7326059389628947e-05 4.761300201275815 0.3615884946766885 TKPTQAAGPSS(ph)PQKPPTPEETK ddPTM_PC-9_AZD4547_30min_R2 1 TKPTQAAGPSSPQKPPTPEETK 22 2 P18887;F5H8D7 P18887 XRCC1 DNA repair protein XRCC1 1 TKPTQAAGPS(0.018)S(0.952)PQKPPT(0.028)PEET(0.001)K 86.258 7.1647e-05 88989000.0 91911.0 76288.0 78337.0 105280.0 95881.0 102900.0 100470.0 96677.0 94020.0 94531.0 True False 121136.78613243742 100946.60410685031 77298.20019551342 81009.32255978555 82569.57817653148 96465.6467332618 109411.63536382011 81737.79106645178 98989.7052543657 91221.49846299719 1.3279411999746418 1.1066097993095123 0.8473682355357101 0.8880507766778895 0.9051548107382247 1.0574880741779509 1.1994062497033144 0.8960364874910234 1.0851576319426455 1.0 16.477086248576285 -4.874417368070054 3.4805259339850556 0.9844792493885133 1.3389177886440062 0.5094966181074743 0.10270562852295942 0.22151448782167535 4.540473482108359 0.027792873506115055 0.1786816790513288 1.3353116311987605e-05 4.874417368070054 0.35443853925549296 TKPTQAAGPSS(ph)PQKPPTPEETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TKPTQAAGPSSPQKPPTPEETK 22 2 P18887;F5H8D7 P18887 XRCC1 DNA repair protein XRCC1 1 TKPTQAAGPS(0.03)S(0.95)PQKPPT(0.019)PEET(0.001)K;TKPTQAAGPS(0.058)S(0.94)PQKPPT(0.001)PEETK 95.227 5.3422e-05 114633000.0 338670.0 307770.0 270310.0 393890.0 404070.0 377840.0 391500.0 345670.0 348030.0 298440.0 True False 396000.14196259767 338323.37161892897 276755.2155563839 371821.6203086095 324895.38414076465 358025.40525069466 354414.28578545456 336596.5287676394 353119.2803419276 352544.80955026054 1.1232618697968433 0.9596606231432714 0.7850213875207495 1.0546790372064767 0.9215718834585365 1.0155458130483488 1.0053028045926387 0.9547624008336238 1.0016294972329898 1.0 18.427447114664226 -6.786986683603311 24.98889392758851 0.9932366579864803 0.9628858095592483 0.02199562154827972 0.08351001176752486 1084.8862376681986 1061164.8310130027 0.02984114649676538 0.02632597490845089 1.633102021523766e-07 6.786986683603311 -0.030350848427232013 TKPTQAAGPSS(ph)PQKPPTPEETK ddPTM_PC-9_Lapatinib_30min_R1 1 TKPTQAAGPSSPQKPPTPEETK 22 2 P18887;F5H8D7 P18887 XRCC1 DNA repair protein XRCC1 1 T(0.002)KPT(0.001)QAAGPS(0.194)S(0.775)PQKPPT(0.011)PEET(0.016)K 60.621 0.0023073 65002000.0 156540.0 146960.0 133340.0 145640.0 156210.0 143210.0 126790.0 144490.0 147130.0 108580.0 True False 154307.7108940795 146619.72314919566 122377.29990728492 156350.8514407973 147022.03492067644 137085.24213881526 133354.56581176553 151203.53288667861 130558.67005241425 127347.90832624456 1.2117019660720953 1.1513320091098775 0.960968275927817 1.2277457360371553 1.154491164032549 1.0764624558074816 1.0471673038408522 1.1873263948656294 1.0252125203183098 1.0 16.958415738154642 -14.522878740086892 0.0925777447788895 0.6131405848207613 1.2087095937795973 0.2267482031798449 0.07870768999151255 354.3484828182174 2.259040261826706 26.645240139098448 1.7249758800004815 3.0000000358750533e-15 14.522878740086892 0.595569008958836 TKPVASVSGQSSGCCIT(ph)PTGYR ddPTM_PC-9_AZD4547_30min_R2 1 TKPVASVSGQSSGCCITPTGYR 22 1 H3BLW0;Q5SQL3;J3KP92;Q86Z02-4;Q86Z02-3;Q86Z02-2;Q86Z02 H3BLW0 HIPK1 Homeodomain-interacting protein kinase 1 1 TKPVASVSGQS(0.001)S(0.014)GCCIT(0.562)PT(0.42)GY(0.003)R 63.931999999999995 0.030732 0.0 4187.1 4709.3 2890.8 6099.6 5180.3 4859.5 4741.5 5349.2 3607.1 5186.2 True False 5518.510702909657 6231.489129619204 2852.466103184834 4693.431457880587 4461.10476348689 4555.63469679577 5163.48431449739 4522.60405238747 3797.7639419593975 5004.632716556424 1.1026804593778103 1.245144145943831 0.5699651232643406 0.9378173631710645 0.8913950365885144 0.9102835222502401 1.0317409102600976 0.9036835085671127 0.7588496812954045 1.0 12.289048480107832 -5.220958024513901 24.998997045514578 0.881647197852232 1.173912443904717 0.4652263598793731 0.12785315040847187 448.9802654072716 277263.44796325674 0.031877802615207236 0.08433839655186401 6.012318450127052e-06 5.220958024513901 0.29226524605248505 TKS(ph)DEETLK ddPTM_PC-9_Lapatinib_30min_R1 1 TKSDEETLK 9 1 P35251-2;P35251;E0CX09 P35251-2 RFC1 Replication factor C subunit 1 1 T(0.005)KS(0.995)DEETLK 120.53 0.00053642 0.0 9491.8 9742.1 7123.3 8162.0 9947.1 11938.0 8354.5 9057.0 11971.0 7391.0 True False 9356.445191417057 9719.542766002836 6537.649770733174 8762.260707633828 9362.031134751045 11427.43956883721 8787.055131117548 9477.821284204063 10622.699919781498 8668.524502111552 1.0793584524261235 1.1212453473062536 0.7541825335027522 1.010813398000945 1.0800028462133968 1.3182681281057254 1.013673679872177 1.093360384676236 1.2254334537779679 1.0 13.081570733167771 -6.3280965150880695 3.989209370251168 1.1340056788279032 0.9829844511146829 0.20790363106794263 0.12601286609109918 0.35437717614203756 11.17914199400398 0.040728929425263974 0.04745926775846214 4.6978969366519263e-07 6.3280965150880695 -0.15102122771322024 TKS(ph)LIAQDHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TKSLIAQDHR 10 1 E9PB39;H0YAN8;O15013-7;O15013-4;O15013-5;O15013-6;O15013 E9PB39 ARHGEF10 Rho guanine nucleotide exchange factor 10 1 T(0.053)KS(0.947)LIAQDHR 53.597 0.041551 9059400.0 37086.0 24121.0 37830.0 28843.0 44160.0 38801.0 44914.0 47131.0 43313.0 32277.0 True False 43363.927318111695 26515.57346986453 38732.01067107395 27227.020220267663 35507.16500521246 36766.20725474329 40659.420770799305 45893.86118942232 43946.37068485444 38128.56459540858 1.137308151467458 0.6954254310705816 1.015826614037761 0.7140845848560039 0.9312484060700311 0.9642693776930343 1.0663769067166902 1.2036608688633623 1.1525839262815165 1.0 15.218584599308329 -7.179344662571741 1.989517030707499 1.1331361736688184 0.8843411692637635 0.3564232609288166 0.13117541997250667 0.3228575842717341 2.5042422817179952 0.05996418925105293 0.04066728397018082 6.616911673024977e-08 7.179344662571741 -0.24879500440505486 TKS(ph)PKPAESPQSATK ddPTM_PC-9_AZD4547_30min_R2 1 TKSPKPAESPQSATK 15 2 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 T(0.194)KS(0.799)PKPAES(0.008)PQSATK 51.771 0.02882 23726000.0 93373.0 96548.0 95803.0 123100.0 112940.0 109290.0 95820.0 100080.0 97552.0 109150.0 True False 123063.67172094867 127755.25290095674 94532.58962343173 94721.19687604114 97260.23048630566 102456.0790231116 104347.79437206355 84614.93560961222 102708.39956364497 105328.69172267416 1.168377482984123 1.2129197734396124 0.8975008430972626 0.8992914971870903 0.9233973088964932 0.972727158644237 0.9906872730063593 0.8033417507206835 0.9751227123761462 1.0 16.68453895702728 -5.260391267872492 24.99989558889143 0.9277018040326155 1.1906486512110828 0.7703281536996135 0.05627204852882909 38.011765389030046 906639.1123222634 0.014301491648142452 0.03372930475596241 5.490460002893066e-06 5.260391267872492 0.2629468471784673 TKS(ph)PSLPPK ddPTM_PC-9_Lapatinib_30min_R1 1 TKSPSLPPK 9 1 P41970 P41970 ELK3 ETS domain-containing protein Elk-3 1 T(0.053)KS(0.61)PS(0.337)LPPK 77.185 0.011054000000000001 8020000.0 48437.0 50204.0 48535.0 37982.0 39479.0 39982.0 36228.0 35325.0 47088.0 26092.0 True False 47746.2794977421 50087.75572252457 44544.639650517944 40775.32298423768 37156.92283870034 38272.06306259417 38103.708575034594 36966.32846025267 41784.45358137762 30601.967434595375 1.5602356155625852 1.6367495269569043 1.4556135890844863 1.3324412252704176 1.21420045682078 1.2506406048693388 1.2451391779457466 1.2079722828037003 1.3654172291596027 1.0 14.901336787921293 -5.70259579901852 1.700956768968174 1.2267920058590855 1.604792667451452 0.7521200935235102 0.08832800591525249 0.1733458570821592 1.0120983745996124 0.025837551505131673 0.05902853648866717 1.9833721056662345e-06 5.70259579901852 0.37800066159236656 TKS(ph)PTDDEVTPSAVVR ddPTM_PC-9_AZD4547_30min_R2 1 TKSPTDDEVTPSAVVR 16 1 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 T(0.167)KS(0.823)PT(0.009)DDEVT(0.001)PSAVVR 66.568 0.012499 43143000.0 14610.0 12109.0 14477.0 15873.0 23626.0 13918.0 15923.0 23070.0 18081.0 17695.0 True False 19255.67609312175 16022.997445598905 14285.025520896248 12213.72508540537 20345.93771444535 13047.705259801125 17340.11615306169 19505.061595860865 19036.72474690692 17075.503435938823 1.1276783823892604 0.9383616422034909 0.8365800501571476 0.7152775981819156 1.1915278393270234 0.7641183352954392 1.0154966275586308 1.1422832520889867 1.1148558411953062 1.0 14.059640493574358 -7.519690425546704 22.373778491435964 1.0929199018843483 0.9242497318800899 0.19855527499813053 0.14197512896774972 51.921799951869986 364395.198881578 0.06455418066096053 0.038387361605524056 3.022105174404693e-08 7.519690425546704 -0.16867017000425844 TKS(ph)PTDDEVTPSAVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TKSPTDDEVTPSAVVR 16 1 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 T(0.014)KS(0.947)PT(0.039)DDEVTPSAVVR 97.77600000000001 0.0010105000000000001 23161000.0 22813.0 20780.0 19967.0 22921.0 30323.0 24541.0 27861.0 26164.0 22272.0 19809.0 True False 26674.79032271158 22842.901069764284 20443.089005269176 21636.810680884628 24381.425825476836 23254.026758038573 25221.804383827726 25477.222723049494 22597.685865515632 23400.214892042288 1.139937835860767 0.9761833887060786 0.8736282593806973 0.9246415377254787 1.0419317060959226 0.9937527012175675 1.077844989893871 1.088760203296831 0.9657042027080028 1.0 14.514234158172668 -6.286365983374826 24.325974524401175 1.0332169726347975 0.9709274736974863 0.09406007764647539 0.0725072973875207 1151.2546867614406 1123510.4679851835 0.023604177905921928 0.026776345480234446 5.171708243425812e-07 6.286365983374826 -0.06228949893731117 TKS(ph)PTDDEVTPSAVVR ddPTM_PC-9_Lapatinib_30min_R1 1 TKSPTDDEVTPSAVVR 16 1 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 T(0.377)KS(0.612)PT(0.011)DDEVTPSAVVR 67.579 0.011669 8114100.0 9622.3 8881.1 11056.0 10055.0 8879.3 11988.0 11193.0 11859.0 10672.0 11170.0 True False 9485.084237486295 8860.536358603153 10147.01835739418 10794.478242496705 8357.037031375461 11475.30118539291 11772.518772230382 12410.012433407977 9470.006978857922 13100.719616910575 0.7240124599905816 0.6763396681786746 0.7745390065669583 0.8239607104149497 0.6379067162530592 0.8759290726732633 0.8986161918185216 0.9472771570035722 0.7228615874378318 1.0 13.677358440108671 -6.854493128946391 8.454223510921972 0.8873730066324217 0.7327150015798372 0.4975561556716037 0.08113908267511646 0.23360016257641955 18.883915892352803 0.027788258543323577 0.02452272353966268 1.3979990331500045e-07 6.854493128946391 -0.15465800505258454 TKS(ph)VSSMSEFESLLDCSPYLAGGDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TKSVSSMSEFESLLDCSPYLAGGDAR 26 1 O94964-2;H0YDM2;O94964-3;O94964;X6R3R3;O94964-4 O94964-2 SOGA1 Protein SOGA1;N-terminal form;C-terminal 80 kDa form 1 T(0.055)KS(0.235)VS(0.235)S(0.235)MS(0.235)EFES(0.003)LLDCSPYLAGGDAR;T(0.291)KS(0.656)VS(0.035)S(0.006)MS(0.006)EFES(0.005)LLDCSPYLAGGDAR 68.895 0.00049729 15016600.0 21919.0 18427.1 21485.0 27345.0 31144.0 27668.0 23599.0 29675.0 24643.0 22377.0 True False 25629.453780016447 20256.420707538662 21997.283882316246 25812.948303686164 25041.55676907464 26217.041373269687 21363.531878035632 28896.062693261487 25003.35725502431 26433.772963765467 0.9695722897805186 0.7663083410493646 0.8321658778135602 0.9765139595875962 0.9473319152510226 0.9918009589174853 0.8081907908992049 1.0931493863123984 0.9458868126505466 1.0 14.690094738983397 -5.762058034153368 24.999995383383673 0.9637122803969078 0.8470447687458417 0.27751562023911447 0.08096256527382456 19.88942433775575 803798.1636225757 0.021761963738909203 0.03460338385645836 1.729585221761164e-06 5.762058034153368 -0.11666751165106615 TKSNS(ph)LSEQLAINTSPDAVK ddPTM_PC-9_AZD4547_30min_R2 1 TKSNSLSEQLAINTSPDAVK 20 1 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 T(0.037)KS(0.037)NS(0.879)LS(0.047)EQLAINTSPDAVK 75.32600000000001 0.0011095 5439300.0 76746.0 60824.0 79432.0 116150.0 100910.0 85921.0 79797.0 96888.0 85803.0 97513.0 True False 101149.63158403279 80484.1685218521 78378.67978005324 89373.4119996114 86900.38833339051 80548.34628735244 86898.77841272754 81916.18586474935 90338.37140970376 94099.099550647 1.0749266684490533 0.8553128447157251 0.8329376174090534 0.949779672987284 0.9234986173976943 0.855994867878612 0.9234815086190699 0.8705310279899071 0.9600343875881713 1.0 16.52189329718943 -8.497892910739447 5.27596861826663 0.9998921277949463 0.9068763727265323 0.16316562098593723 0.06533403698958737 0.2584826014198069 22.49267563566569 0.060850001811742 0.01581081674475387 3.177657527629919e-09 8.497892910739447 -0.09301575506841397 TKSNS(ph)LSEQLAINTSPDAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TKSNSLSEQLAINTSPDAVK 20 1 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 T(0.182)KS(0.049)NS(0.693)LS(0.076)EQLAINTSPDAVK 113.3 1.3202999999999999e-05 7054000.0 58630.0 60974.0 41357.0 67948.0 71395.0 51001.0 57054.0 39997.0 48787.0 55273.0 True False 68554.90100471576 67027.09575687238 42343.107727295894 64141.09385038818 57405.66226329587 48326.41777787073 51649.43208481059 38947.12113032453 49500.4175790639 65293.55735917278 1.049948934894184 1.0265499149964152 0.6485036110740765 0.9823495065149379 0.8791933627924964 0.7401406774642764 0.7910341260883162 0.5964925592287863 0.758121008888633 1.0 15.994653024850669 -6.679826460305819 4.404838706650933 0.7525642203755345 0.9157149191396932 0.19566458805207498 0.13916927834667758 0.33023911231992026 11.85760834381216 0.04752956241736803 0.04678492900099058 2.0901311593362845e-07 6.679826460305819 0.16315069876415866 TKSPT(ph)DDEVTPSAVVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TKSPTDDEVTPSAVVR 16 1 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 T(0.002)KS(0.092)PT(0.905)DDEVTPSAVVR 122.5 0.00058837 6593700.0 17685.0 16972.0 20502.0 23506.0 24640.0 15614.0 23588.0 22115.0 14294.0 12218.0 True False 20678.7212053283 18656.86799595955 20990.845434267994 22189.035027480208 19811.96887971999 14795.174353123932 21353.573877668736 21534.504682779374 14503.022708408776 14433.026682365222 1.4327362971340092 1.2926511123793019 1.4543619918554813 1.5373792008984193 1.372682897061844 1.0250915957358546 1.479493826735544 1.4920297146745378 1.0048497122318134 1.0 13.817086251919044 -8.272512986539821 24.33996718710364 1.002424694005719 1.3806980161071485 0.5540404393773695 0.1375219693622176 452.22074383608555 993973.416989582 0.1338546644280401 0.03595276977855844 5.339333073344036e-09 8.272512986539821 0.3782733221014294 TKSPT(ph)DDEVTPSAVVR ddPTM_PC-9_Lapatinib_30min_R1 1 TKSPTDDEVTPSAVVR 16 1 Q5VTI5;A0A1B0GUN5;Q9Y2H5 Q5VTI5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 T(0.018)KS(0.238)PT(0.742)DDEVT(0.002)PSAVVR 116.04 0.0017112000000000002 19707000.0 21509.0 21279.0 27606.0 20599.0 20831.0 22928.0 24236.0 21275.0 23059.0 15553.0 True False 21202.277715732478 21229.729782877876 25336.341242241637 22113.91917624959 19605.761535321733 21947.422887778495 25490.82149234123 22263.51416820596 20461.85259796523 18241.315326930173 1.1623217589156496 1.1638266979320193 1.3889536356425392 1.212298498212033 1.0747997709560555 1.2031710704203928 1.397422336902888 1.2204993866499143 1.1217312036570528 1.0 14.15492214124629 -8.516562013390448 2.778811020536675 1.0015694160003517 1.230043254708885 0.37212704365604843 0.09358445496000832 0.28620191226989117 5.310794370196658 0.09518128115808136 0.025585531505915995 3.0439533095220034e-09 8.516562013390448 0.22847383870853344 TKSS(ph)DDLLAGMAGGVTVTNGVK ddPTM_PC-9_AZD4547_30min_R2 1 TKSSDDLLAGMAGGVTVTNGVK 22 1 Q69YQ0-2;Q69YQ0;F8WAN1;C9J8U1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 T(0.289)KS(0.289)S(0.422)DDLLAGMAGGVTVTNGVK 90.12700000000001 0.00031203 10399000.0 129610.0 108990.0 125450.0 133460.0 154640.0 160570.0 129480.0 129680.0 126390.0 135640.0 True False 170823.2839445247 144218.8860843858 123786.45103242616 102692.8589364456 133170.90528070016 150529.53251661645 141003.4691640035 109640.9357499453 133070.71736970104 130891.28488560252 1.3050776000390116 1.10182191435 0.9457195804947144 0.7845660543877919 1.01741613581905 1.1500347990943594 1.0772563604004568 0.8376488613872972 1.0166507073866937 1.0 16.998009516174555 -4.878462161988363 2.7497560562590166 0.977906700744365 1.3322912650354188 0.4974090069165704 0.10091754915205972 0.32526491444324485 3.9034613051649067 0.028612290919437896 0.2397271847258079 1.3229329638430369e-05 4.878462161988363 0.3543845642910538 TLADLIR ddPTM_PC-9_Lapatinib_30min_R1 1 TLADLIR 7 0 Q16878 Q16878 CDO1 Cysteine dioxygenase type 1 0 115.46 0.037868 3663600.0 31501.0 33680.0 33422.0 29095.0 33115.0 35051.0 31448.0 29117.0 29897.0 26122.0 False True 31051.789963424097 33602.01602929304 30674.17217265088 31234.74335807478 31167.240806594964 33551.950437871754 33076.22356375421 30469.882116834462 26529.685030632994 30637.1528946229 1.0135337989867188 1.0967734549247394 1.001208313257936 1.0195054176707379 1.0173021270545377 1.0951393085798264 1.079611531708594 0.9945402636346866 0.8659318025366906 1.0 14.902994613638123 -8.011332575412421 7.173531174304951 0.9315311590017493 1.0456340787249678 0.5104301562959543 0.044392845675092024 0.11063036364016722 32.08070959019217 0.02681289225206337 0.011266502395055344 9.74243292851033e-09 8.011332575412421 0.11410291972321851 TLAGMGLQPGNIS(ph)PTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLAGMGLQPGNISPTSK 17 0 P24723-2;P24723;G3V4H0;G3V4Q6 P24723-2 PRKCH Protein kinase C eta type 1 TLAGMGLQPGNIS(0.998)PT(0.002)SK 156.06 3.6763e-17 0.0 30180.0 39069.0 33705.0 39165.0 46749.0 37334.0 39177.0 46374.0 30968.0 30518.0 True False 35288.87791782912 42947.512121974076 34508.655026924316 36970.71202464319 37588.86904050446 35376.1393172492 35465.87094308241 45156.73163731449 31420.84841429993 36050.671819644944 0.9788688015128556 1.1913096193278392 0.9572264061975028 1.0255207506146082 1.0426676437142377 0.981289322269213 0.9837783639792294 1.2525905720488522 0.8715745595946952 1.0 15.137738524503455 -7.368497349112645 0.0051750914402243185 0.0001380584594822071 2.06435665239274 0.013361708585023724 0.10612158272256574 39149.844415115505 134.88164534637937 26711.87943180176 27078.733561451587 4.280580323989598e-08 7.368497349112645 2.0642185939332576 TLDDSANRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLDDSANRR 9 1 A0A1B0GTG9;A0A1B0GWF8;A0A1B0GWJ0;A0A1B0GTJ7;A0A0A6YY92;P30566-2;P30566 A0A1B0GTG9 ADSL Adenylosuccinate lyase 0 90.15 0.0055655 1679600.0 7865.8 7968.1 10132.0 10648.0 10828.0 11087.0 10747.0 11272.0 10461.0 8751.0 False True 9197.324583368463 8759.120308661642 10373.585305823979 10051.427081281769 8706.33112944838 10505.578202451976 9728.966358457943 10976.121943671218 10613.972334732347 10337.487027122112 0.8897060338975765 0.8473162080572036 1.0034919781381255 0.972327902797864 0.8422096305036104 1.016260351755591 0.9411345651929126 1.061778545876144 1.0267458916160987 1.0 13.335597898458131 -7.263266978641286 1.3556665444714273 1.0289705179059598 0.9177672900219025 0.3862797708182987 0.0572966517196484 0.4720859560172414 1.6918475609483827 0.03611616002455076 0.02100447795409839 5.454224644379946e-08 7.263266978641286 -0.11120322788405734 TLDDSANRR ddPTM_PC-9_Lapatinib_30min_R1 2 TLDDSANRR 9 1 A0A1B0GTG9;A0A1B0GWF8;A0A1B0GWJ0;A0A1B0GTJ7;A0A0A6YY92;P30566-2;P30566 A0A1B0GTG9 ADSL Adenylosuccinate lyase 0 ; 101.46 0.0022091999999999997 2604130.0 23249.9 17965.0 19470.7 24456.9 20777.3 24611.5 19693.6 18148.8 25751.6 18559.5 False True 22918.352162490522 17923.403146266308 17869.89420507551 26255.542011826747 19555.220063743483 23558.92351720866 20713.23824647514 18992.059503451765 22851.18363163022 21767.484846020747 1.0528709368404665 0.8234025783434891 0.8209443732927305 1.2061817062262226 0.898368378435707 1.0822988362624448 0.9515678266458822 0.872496737119523 1.0497852091445274 1.0 14.409887098522484 TLDFDPLLS(ph)PASPK ddPTM_PC-9_AZD4547_30min_R2 2 TLDFDPLLSPASPK 14 0 Q53H80 Q53H80 AKIRIN2 Akirin-2 1 TLDFDPLLS(0.724)PAS(0.276)PK;TLDFDPLLS(0.989)PAS(0.011)PK 141.59 0.00013654 15769000.0 52131.0 40423.2 49033.0 54744.0 57646.0 59300.0 47321.0 53766.0 53142.0 55641.0 True False 68707.5736078391 53489.20888123993 48382.79038240697 42123.61658636877 49642.84794239041 55591.961625679454 51532.47732707603 45457.70011976836 55950.9776284568 53693.025525802346 1.2796368417499862 0.9962040387449489 0.901100094632523 0.7845267830200058 0.9245679016268954 1.0353665318964858 0.9597611016036327 0.8466220644974368 1.042052986966983 1.0 15.712447080556869 -4.7706827255141055 3.2004409324162255 0.9302783581321985 1.335277571432812 0.6409919966634039 0.07649182279713211 0.22599235682440844 3.4645718892211455 0.020126458338965963 0.23512270744034522 1.6955760537204983e-05 4.7706827255141055 0.4049992133006135 TLDFDPLLS(ph)PASPK ddPTM_PC-9_Lapatinib_30min_R1 1 TLDFDPLLSPASPK 14 0 Q53H80 Q53H80 AKIRIN2 Akirin-2 1 TLDFDPLLS(0.884)PAS(0.116)PK 175.6 0.00011372 3071700.0 24071.0 25039.0 20883.0 22640.0 23699.0 17414.0 21379.0 20134.0 21195.0 19014.0 True False 23727.74312591922 24981.02373389156 19166.080350711167 24305.021124825995 22305.071414026694 16669.24381401669 22485.900011749607 21069.499142780678 18807.795906755404 22300.544565437547 1.0639983726089637 1.120197924341648 0.8594444989659883 1.0898846462473872 1.0002029927375031 0.7474814691230223 1.0083117004505502 0.9447975174308164 0.8433783243080363 1.0 14.444791319841382 -5.0905494892693275 0.6658181218284763 0.918944459583959 1.1604538795189585 0.23048946602225606 0.09901409016156673 3.4344592379761973 1.5136469862663608 0.04757938272066683 0.5918366199192783 8.118027361014697e-06 5.0905494892693275 0.24150941993499953 TLDFDPLLS(ph)PASPKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLDFDPLLSPASPKR 15 1 Q53H80 Q53H80 AKIRIN2 Akirin-2 1 TLDFDPLLS(0.5)PAS(0.5)PKR 70.335 0.010968 8161800.0 25302.0 19208.0 26072.0 30253.0 34308.0 29829.0 29627.0 37346.0 27767.0 26319.0 True False 29585.12886272076 21114.84329875037 26693.655358610617 28558.022491549364 27585.59368203871 28264.71472904661 26820.516079094952 36365.70707135785 28173.03984499695 31090.426358910627 0.9515832469194029 0.679142931492761 0.8585811931446904 0.9185471489478153 0.8872697133062178 0.9091131270686431 0.8626615720696958 1.169675405912705 0.9061644739047606 1.0 14.924182780778711 -6.996376864156347 0.7397465073904114 1.0204683947485382 0.8256815819089455 0.2942007477938874 0.09792440721098211 0.78436515090065 0.8996617119748901 0.0742260541746376 0.05848421366959868 1.0083774748663569e-07 6.996376864156347 -0.19478681283959276 TLDFDPLLSPAS(ph)PKR ddPTM_PC-9_AZD4547_30min_R2 2 TLDFDPLLSPASPKR 15 1 Q53H80 Q53H80 AKIRIN2 Akirin-2 1 TLDFDPLLS(0.024)PAS(0.976)PKR;TLDFDPLLS(0.112)PAS(0.888)PKR 76.76100000000001 0.0062419 25610000.0 52511.0 45755.0 63469.0 85207.0 77822.0 68801.0 62886.0 72668.0 61249.0 68946.0 True False 69208.4057033481 60544.40896220815 62627.35959009209 65563.84258502704 67017.75860550109 64498.86259373312 68482.73217367564 61438.83034451748 64486.497097688276 66532.22152552906 1.0402238812481581 0.910001313258068 0.9413087095860967 0.9854449630825803 1.0072977734523072 0.9694379823013166 1.0293167822060194 0.9234447450539857 0.9692521250465712 1.0 16.02176558597889 -5.785654191591899 24.439547648372123 0.9825866912939988 0.9584602948064329 0.04209071228523242 0.04035088099610127 504.75330561149707 509435.6681622005 0.011248812409892065 0.01669497432808422 1.6381203609851755e-06 5.785654191591899 -0.02412639648756587 TLDFDPLLSPAS(ph)PKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLDFDPLLSPASPKR 15 1 Q53H80 Q53H80 AKIRIN2 Akirin-2 1 TLDFDPLLS(0.002)PAS(0.998)PKR 150.59 6.424600000000001e-05 9156400.0 30200.0 27059.0 31152.0 38435.0 39671.0 33869.0 34614.0 35823.0 32486.0 28416.0 True False 35312.26352281111 29745.238693298932 31894.7818246179 36281.61155795125 31897.75233065631 32092.850017033063 31335.111336341608 34882.684207605955 32961.04629252605 33567.595859067755 1.0519747577714018 0.8861295523868662 0.9501658074807294 1.0808522513878618 0.9502543007422332 0.9560663847292981 0.9334928681786105 1.039177317138217 0.9819305031826444 1.0 15.034781593188903 -7.767561406206953 24.999936916813883 1.007915418959817 0.9711644641563669 0.07559818483676639 0.054802474170844065 413.14306226665036 1687078.1741166606 0.029126891459596096 0.014551789664708078 1.7078062311126477e-08 7.767561406206953 -0.03675095480345003 TLDFDPLLSPAS(ph)PKR ddPTM_PC-9_Lapatinib_30min_R1 2 TLDFDPLLSPASPKR 15 1 Q53H80 Q53H80 AKIRIN2 Akirin-2 1 TLDFDPLLS(0.01)PAS(0.99)PKR;TLDFDPLLSPAS(1)PKR 132.62 2.8375999999999997e-06 15106900.0 79881.0 65636.0 71859.0 66485.0 66161.0 64402.0 56685.0 49364.0 66363.0 54302.0 True False 78741.88229161868 65484.02387466388 65951.03040376154 71374.52868745846 62269.54005753074 61647.67658839451 59619.87193816486 51657.631652141914 58888.50010662937 63688.02834713316 1.2363686604087367 1.0281998921012534 1.0355326128843845 1.1206898775140257 0.977727552156727 0.9679633392382999 0.9361236873781881 0.8111042686167128 0.9246400247414814 1.0 15.958734589277395 -6.460952153879927 0.9128393513300026 0.8989876542174524 1.1175298923225354 0.585693349330514 0.0703072000950347 0.4059067492778503 0.7369539141935119 0.03739529331398719 0.04794687589347043 3.459774919848084e-07 6.460952153879927 0.218542238105083 TLDPLVNT(ph)SS(ph)LIMR ddPTM_PC-9_Lapatinib_30min_R1 2 TLDPLVNTSSLIMR 14 0 J3KNS1;Q9UPW5 J3KNS1 AGTPBP1 Cytosolic carboxypeptidase 1 2 T(0.077)LDPLVNT(0.828)S(0.101)S(0.995)LIMR;T(0.026)LDPLVNT(0.728)S(0.268)S(0.979)LIMR 112.08 0.0033790999999999995 163060000.0 90611.0 79302.0 77438.0 74009.0 83006.0 75060.0 77462.0 73158.0 71374.0 75677.0 True False 89318.87052397765 79118.38109130025 71071.34655932427 79451.86874678673 78123.75027607485 71849.85877340594 81472.60333552308 76557.18775640939 63335.10851846002 88757.66861673615 1.0063228554330874 0.8913976935665218 0.8007347158499278 0.8951549762969471 0.8801915540776589 0.8095059265657405 0.9179218495173566 0.8625416704779666 0.7135733678624087 1.0 16.437584152545767 -4.803160015422968 3.632441684948092 0.8566979579807233 1.0194696815859203 0.2669729615350399 0.07232424053410068 0.3214611161387797 7.248474352810778 0.017233232787960653 0.13728006694045863 1.5734030386777013e-05 4.803160015422968 0.16277172360519698 TLDPLVNTS(ph)S(ph)LIMR ddPTM_PC-9_AZD4547_30min_R2 1 TLDPLVNTSSLIMR 14 0 J3KNS1;Q9UPW5 J3KNS1 AGTPBP1 Cytosolic carboxypeptidase 1 2 T(0.016)LDPLVNT(0.417)S(0.57)S(0.997)LIMR 89.46 0.018453 72869000.0 107300.0 104650.0 109550.0 151250.0 126100.0 119020.0 102370.0 117490.0 104860.0 117020.0 True False 141419.16802135244 138476.0659577115 108097.29542130158 116381.6492892056 108593.19164444094 111577.66058496395 111480.73168303256 99334.6201516122 110402.68552406703 112923.16541811592 1.2523485991357535 1.2262857266264358 0.9572641275247129 1.0306268767642501 0.9616555756505535 0.9880847758015813 0.9872264142636941 0.8796655653763337 0.9776796914546593 1.0 16.784981949968397 -5.246811322522997 6.99945823646795 0.9710416239187198 1.2412272507261417 0.8908166414946643 0.03732529219496614 0.04607612093297008 12.243899807936582 0.009907992967807103 0.02472078138219719 5.664853428464725e-06 5.246811322522997 0.27018562680742186 TLDPLVNTS(ph)S(ph)LIMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLDPLVNTSSLIMR 14 0 J3KNS1;Q9UPW5 J3KNS1 AGTPBP1 Cytosolic carboxypeptidase 1 2 T(0.012)LDPLVNT(0.294)S(0.705)S(0.989)LIMR 83.53 0.027627 89093000.0 60279.0 62506.0 51673.0 67722.0 78877.0 47155.0 54003.0 82859.0 59644.0 56315.0 True False 70483.04413548102 68711.18259223706 52905.08029094376 63927.7558976864 63421.618073282225 44682.10878836681 48887.44489213774 80684.03904636763 60516.18066463782 66524.46371070531 1.0595056345285303 1.0328708983065407 0.795272555988003 0.9609661218118014 0.9533578256125984 0.6716643216046916 0.7348792033068374 1.212847643496053 0.9096831043660014 1.0 16.02159735450721 -10.723926799573935 5.9148338108867025 1.0000014631157872 0.9222058969762797 0.020520177330262235 0.15237278218188402 3.0721424777233293e-06 4.1520833208068e-07 0.15417097528785284 0.03739125070403981 1.8883095972540386e-11 10.723926799573935 -0.07779556613950744 TLDPLVNTS(ph)S(ph)LIMR ddPTM_PC-9_Lapatinib_30min_R1 1 TLDPLVNTSSLIMR 14 0 J3KNS1;Q9UPW5 J3KNS1 AGTPBP1 Cytosolic carboxypeptidase 1 2 T(0.006)LDPLVNT(0.438)S(0.587)S(0.968)LIMR 83.87700000000001 0.026211 96777000.0 10835.0 10148.0 10674.0 8359.0 8850.3 9918.7 10656.0 7576.3 10151.0 7233.3 True False 10680.490913104348 10124.502929491257 9796.424922831533 8973.748744806566 8329.742754359273 9494.500322619004 11207.715539791556 7928.322556642956 9007.687485231141 8483.566267233591 1.2589623958447786 1.1934253367708718 1.1547531561895905 1.0577802379485413 0.9818680601967551 1.1191638072410635 1.3211089754882392 0.9345506720758257 1.0617807654808902 1.0 13.050455147856479 -5.357279707416345 1.940725441855151 1.0750942624873934 1.2433357270213157 0.2930426984843273 0.09953118675961245 0.5298534631287768 3.686127654606392 0.02996644312126579 0.10261518810516082 4.3925861974594644e-06 5.357279707416345 0.1682414645339223 TLDS(ph)DEERPR ddPTM_PC-9_Lapatinib_30min_R1 1 TLDSDEERPR 10 1 Q9BW71;Q9BW71-2 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 T(0.069)LDS(0.931)DEERPR 61.48 0.046415 0.0 10628.0 13487.0 15323.0 10042.0 14772.0 12822.0 13466.0 12379.0 15225.0 11259.0 True False 10476.442771063501 13455.771680138805 14063.202088490498 10780.522179129983 13903.140002869415 12273.632949541858 14163.20359035597 12954.173531761297 13510.200173642423 13205.103148325528 0.7933631909866576 1.0189827015357364 1.0649823731421424 0.8163906073310003 1.0528611436581168 0.9294613462446307 1.0725553167793267 0.9809975269601698 1.0231044787677848 1.0 13.688807950346126 TLDSGTSEIVKS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 TLDSGTSEIVKSPR 14 1 Q9H501 Q9H501 ESF1 ESF1 homolog 1 TLDS(0.001)GTS(0.001)EIVKS(0.998)PR;TLDSGTSEIVKS(1)PR 79.471 0.0060085 285990000.0 142903.0 110592.0 148340.0 221166.0 166568.0 153330.0 142976.0 157477.0 146321.0 184780.0 True False 188343.18143294842 146338.70125556833 146372.9146763658 170179.59568063778 143442.90837296794 143742.25086113688 155700.58701878748 133142.54811145988 154055.229339758 178310.90844265438 1.0562628112767452 0.8206940480179963 0.8208859231034651 0.9543981193689467 0.8044539149386918 0.8061326820471282 0.873197205816836 0.7466876214938871 0.8639697407480983 1.0 17.44403543917609 -4.757207604536444 24.99789288521645 0.8461566568688337 1.0562631201136115 0.41411371776950945 0.07138247367127125 115.47552702711074 682046.5773735996 0.016778143461825094 0.12678381667710853 1.7490104143644646e-05 4.757207604536444 0.21010646324477777 TLDSGTSEIVKS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TLDSGTSEIVKSPR 14 1 Q9H501 Q9H501 ESF1 ESF1 homolog 1 TLDS(0.009)GT(0.001)S(0.007)EIVKS(0.982)PR;TLDSGTSEIVKS(1)PR;TLDSGTSEIVKS(0.999)PR;TLDSGTSEIVKS(1)PR 169.37 0.00051573 162089300.0 248374.0 210704.0 250084.0 301811.0 327843.0 316801.0 340187.0 319852.0 281497.0 245793.0 True False 290418.8125898896 231621.30062577606 256046.95100885112 284901.5081544638 263604.5175906672 300187.39786371286 307962.024619404 311456.22391120694 285613.3610849975 290353.32520368317 1.000225543778982 0.7977222250280532 0.8818461122469802 0.9812235074442667 0.9078749740708095 1.0338693302483486 1.0606457646158118 1.0726800655467612 0.983675185688469 1.0 18.147450030700227 -6.764936475868266 8.724178769260979 1.0367698734174384 0.9092018696168566 0.5065045770454013 0.05717307890005059 0.09122205427187319 70.45355474120026 0.01980631211688452 0.01844233004686837 1.7181596835123356e-07 6.764936475868266 -0.12756800380058186 TLDSGTSEIVKS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 TLDSGTSEIVKSPR 14 1 Q9H501 Q9H501 ESF1 ESF1 homolog 1 TLDSGT(0.002)S(0.001)EIVKS(0.997)PR 95.06700000000001 0.024426 0.0 14982.0 11734.0 13430.0 12255.0 11935.0 13476.0 13399.0 11414.0 14499.0 10374.0 True False 14768.35393263769 11706.830643934809 12325.837241299188 13156.273581481575 11233.006765112808 12899.662894090321 14092.73465818948 11944.336108855605 12865.969938761335 12167.132077513894 1.2137908784545144 0.9621684526274051 1.0130437610748548 1.0812961918771076 0.9232255139132216 1.0602057092755834 1.1582626512483 0.9816887030370913 1.0574365312051608 1.0 13.57070152910143 TLEAEFNS(ph)PSPPTPEPGEGPR ddPTM_PC-9_Lapatinib_30min_R1 1 TLEAEFNSPSPPTPEPGEGPR 21 0 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 T(0.016)LEAEFNS(0.526)PS(0.343)PPT(0.116)PEPGEGPR 51.004 0.038843 2714600.0 987.73 710.02 2467.1 1096.0 1133.5 1242.4 681.49 0.0 615.71 639.08 True False 973.6447890725018 708.375992313499 2264.2645612814017 1176.6034961488213 1066.8297585467428 1189.2654481758552 716.7742176438205 0.0 546.362256086264 749.5441264794275 1.2989826144668284 0.9450757697758325 3.020855585803257 1.5697588101654147 1.4233048073601624 1.586651680884723 0.956280213962151 0.0 0.728926072241405 1.0 9.549869603477022 -7.380314832861274 3.0659542274197173 0.5150990471136359 1.6662772837033621 0.4256614937012405 0.5599706643286116 0.249139953134099 4.460579066351796 0.27071108466931615 0.17017250782649967 4.165672920868395e-08 7.380314832861274 1.1511782365897263 TLEAEFNSPS(ph)PPTPEPGEGPR ddPTM_PC-9_AZD4547_30min_R2 1 TLEAEFNSPSPPTPEPGEGPR 21 0 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 TLEAEFNS(0.135)PS(0.821)PPT(0.044)PEPGEGPR 131.3 1.906e-05 3337900.0 14673.0 15814.0 22771.0 28041.0 20361.0 20729.0 17961.0 24223.0 17880.0 17641.0 True False 19338.708782640337 20925.566240375032 22469.0416616929 21576.580679131337 17534.22660644298 19432.812353097946 19559.49420493254 20479.89193916505 18825.100297256537 17023.393959502493 1.1360078271492642 1.2292241071407701 1.319892009498531 1.2674664482570612 1.0300076851981292 1.1415357242702189 1.1489773573626538 1.2030439986224446 1.1058370817264866 1.0 14.05523107582171 -6.241093724904696 24.7686769506931 1.119088126363899 1.2433491030235895 0.45784059012322365 0.0699291662322379 734.6920538255075 894409.4810442983 0.021120340072054992 0.027232107912816467 5.739925757498327e-07 6.241093724904696 0.12426097665969049 TLEAEFNSPSPPT(ph)PEPGEGPR ddPTM_PC-9_AZD4547_30min_R2 2 TLEAEFNSPSPPTPEPGEGPR 21 0 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 TLEAEFNS(0.008)PS(0.012)PPT(0.98)PEPGEGPR;TLEAEFNS(0.049)PS(0.039)PPT(0.912)PEPGEGPR 256.12 1.0116999999999998e-72 10290900.0 10110.8 13647.8 17670.1 26476.0 22436.0 18385.5 16169.800000000001 28127.0 21047.6 16751.5 True False 13325.824082295372 18059.184452724825 17435.782928561755 20372.367250122366 19321.148673550153 17235.85177856541 17608.880874946735 23780.618444160318 22160.133166472977 16165.035083759769 0.8243609749837899 1.1171757041757377 1.0786108930922547 1.2602736180009595 1.1952432254824599 1.0662427696109018 1.0893190632563197 1.4711145581150986 1.3708682382468933 1.0 13.980589018167874 -4.098385504481217 0.8662261180369419 1.2184085004988852 2.890783606790675e-20 0.3911438705858785 0.13770443112980854 7.163234374274849 1.7953927602217166 0.050380421183212586 11.004155280233585 7.972866560910767e-05 4.098385504481217 -1.2184085004988852 TLEAEFNSPSPPT(ph)PEPGEGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TLEAEFNSPSPPTPEPGEGPR 21 0 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 TLEAEFNSPS(0.05)PPT(0.95)PEPGEGPR;TLEAEFNS(0.002)PS(0.049)PPT(0.948)PEPGEGPR;TLEAEFNS(0.001)PS(0.001)PPT(0.998)PEPGEGPR 260.89 2.5792999999999996e-73 9384600.0 39697.7 42197.5 46965.2 50383.3 63739.6 50122.7 57781.6 59093.5 51203.6 50116.1 True False 46417.736544685366 46386.58892643787 48085.02848451285 47560.48704586251 51250.282938547054 47494.17737602954 52308.10854544277 57542.35823973874 51952.35578230584 59201.75221117071 0.7840601808391553 0.7835340542114096 0.8122230624694203 0.80336282744159 0.8656886160351973 0.8022427648191791 0.8835567629630532 0.9719705260494156 0.8775476036079726 1.0 15.853352255892807 -7.59373413880077 0.40895834760474514 1.0010742691704841 0.7719498898983431 0.7866770188309339 0.033766317847031636 0.48105806980071847 0.20699910737780655 0.03810405296513999 0.03553287683206523 2.5483898179634157e-08 7.59373413880077 -0.22912437927214102 TLEAEFNSPSPPT(ph)PEPGEGPR ddPTM_PC-9_Lapatinib_30min_R1 1 TLEAEFNSPSPPTPEPGEGPR 21 0 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 TLEAEFNS(0.001)PS(0.015)PPT(0.984)PEPGEGPR 146.34 9.3371e-05 3529000.0 13987.0 12544.0 11971.0 10814.0 14520.0 13658.0 14081.0 12565.0 15549.0 13348.0 True False 13787.542815098346 12514.955138701056 10986.790589396316 11609.297634446482 13665.962147418346 13073.879178353045 14810.04528113786 13148.815770787693 13797.707881771155 15655.184014907985 0.8807014214568709 0.799412841572697 0.7017988788208371 0.7415625152276255 0.8729352612147286 0.835115011481383 0.9460154072309004 0.839901706569942 0.8813507314019428 1.0 13.934352845920312 -6.3770656757158335 4.671607724602477 0.8895383204943897 0.7769046788193303 0.44629721737753425 0.06260063437658908 0.23306292561769643 7.9669572779399696 0.020146221482194675 0.022927515741732678 4.1969551118963326e-07 6.3770656757158335 -0.1126336416750594 TLEDEEEQERER ddPTM_PC-9_AZD4547_30min_R2 1 TLEDEEEQERER 12 1 E9PDI4;O00515;A0A0J9YYF6;A0A0J9YVY2;A0A0J9YW63 E9PDI4 LAD1 Ladinin-1 0 99.75200000000001 0.0083996 0.0 13430.0 13945.0 23557.0 28912.0 19711.0 17529.0 11951.0 20007.0 19032.0 17795.0 False True 17700.46063864648 18452.448540662048 23244.61878812964 22246.785085947195 16974.467886626262 16432.908858963485 13014.615847845273 16915.377865123035 20037.99266540194 17172.002466376445 1.0307744057983208 1.0745659148834141 1.3536347221964153 1.2955265484912084 0.9884967067680682 0.9569593814780694 0.7578973898547054 0.9850556391570585 1.1668990092819538 1.0 14.067770664658912 -6.365235380754319 6.268016415966594 0.9609244130066835 1.1915780485352176 0.3983832043809804 0.1275428227191455 0.2549237617165253 13.097703898611513 0.04327217675065998 0.04911214105304027 4.3128526366643537e-07 6.365235380754319 0.23065363552853413 TLEDEEEQERER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLEDEEEQERER 12 1 E9PDI4;O00515;A0A0J9YYF6;A0A0J9YVY2;A0A0J9YW63 E9PDI4 LAD1 Ladinin-1 0 ; 101.39 0.0035445 3594800.0 33568.0 37741.0 36019.0 36822.0 39552.0 39220.0 37846.0 45144.0 42052.0 31698.0 False True 39250.39940177892 41487.67705842031 36877.829562818166 34758.98271853472 31802.069526407675 37163.23415713595 34260.95289868794 43959.017834021804 42666.930945432076 37444.59647877005 1.0482259950119293 1.1079750073403132 0.9848638530188668 0.9282776685346844 0.8493099810659859 0.992485903225219 0.9149772228981786 1.1739749381181137 1.1394683067187794 1.0 15.192469922112318 -7.7622305095419035 24.999998321442796 1.117541224650004 0.9746638173947025 0.3563289592147749 0.07906593447084292 23.173667259571936 732204.2066710787 0.04347132476434325 0.02282035025065108 1.728898471945276e-08 7.7622305095419035 -0.14287740725530151 TLEDEEEQERER ddPTM_PC-9_Lapatinib_30min_R1 2 TLEDEEEQERER 12 1 E9PDI4;O00515;A0A0J9YYF6;A0A0J9YVY2;A0A0J9YW63 E9PDI4 LAD1 Ladinin-1 0 ; 86.463 0.011807 3401600.0 29836.0 34158.0 34184.0 25817.0 31790.0 28782.0 26307.9 27457.0 31228.0 26549.0 False True 29410.53316874771 34078.90924966127 31373.52347405596 27715.668302987324 29920.174701544718 27551.060954119002 27669.994336456697 28732.75245670651 27710.77379458163 31137.959275681173 0.9445234643786502 1.0944490275660739 1.0075651778040176 0.8900926376582853 0.9608906748398394 0.8848062491891192 0.8886258117135838 0.9227564402124087 0.8899354498232586 1.0 14.92638677549725 -5.680988299144359 5.697936790417933 0.9154841750132199 1.0262558612720105 0.4462436415302323 0.048658972379548235 0.1571328026794329 8.39511283041839 0.012469287244907243 0.02175085781097721 2.084547044656995e-06 5.680988299144359 0.11077168625879064 TLEDPDLNVR ddPTM_PC-9_Lapatinib_30min_R1 2 TLEDPDLNVR 10 0 A0A0C4DGH5;Q86VP6-2;Q86VP6 A0A0C4DGH5 CAND1 Cullin-associated NEDD8-dissociated protein 1 0 ; 116.52 0.0027554000000000003 1667600.0 13387.3 11817.1 15142.7 13247.7 14672.0 15703.0 12107.8 12945.2 16454.800000000003 12149.9 False True 13196.394647069857 11789.738230990464 13897.72565851238 14221.980051031695 13809.021806261844 15031.419295480879 12734.682640079607 13546.681250776019 14601.487147274298 14249.994026275892 0.9260631704642628 0.827350398130069 0.9752794024254356 0.9980341061762874 0.9690545680790512 1.0548368839849405 0.8936623142857346 0.9506446968186079 1.0246661942699962 1.0 13.798673694036376 -5.31668569073324 9.50104881911436 0.9809749379908408 0.8768135386695772 0.45624981766459527 0.04648230296695121 0.39632769498907294 66.47068579894751 0.011995003836897063 0.02506328700356745 4.822967209790036e-06 5.31668569073324 -0.10416139932126356 TLEEMELR ddPTM_PC-9_AZD4547_30min_R2 1 TLEEMELR 8 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;K7EPP6;O15083 X6RM00 ERC1;ERC2 ELKS/Rab6-interacting/CAST family member 1;ERC protein 2 0 69.628 0.030004000000000003 0.0 6760.6 6419.5 6241.7 10189.0 9879.7 8849.9 4199.2 9049.1 8282.6 8989.0 False True 8910.330170784313 8494.477834835427 6158.93097974567 7840.083468480773 8508.074191035541 8296.514353981458 4572.920665071696 7650.769522631321 8720.401326736966 8674.297846038658 1.027210539565856 0.9792697905473293 0.7100206943618271 0.9038291752987418 0.980837220723401 0.956447945555648 0.5271804987835457 0.8820044755697709 1.0053149524626206 1.0 13.082531265979958 TLEEVVMAEEEDEGTDRPGS(ph)PA ddPTM_PC-9_AZD4547_30min_R2 1 TLEEVVMAEEEDEGTDRPGSPA 22 1 F8WC89;A6NKF1 F8WC89 SAC3D1 SAC3 domain-containing protein 1 1 TLEEVVMAEEEDEGT(0.103)DRPGS(0.897)PA 63.372 0.0062286 737760.0 5035.7 4107.6 5203.5 6874.8 5716.4 5011.0 3938.9 6189.7 4447.8 5089.0 True False 6636.947850933137 5435.301371504012 5134.498190093496 5289.921074601199 4922.776532246479 4697.661377846197 4289.454469339613 5233.224090156045 4682.9016276363345 4910.835658971045 1.3514905225567577 1.1067976509405035 1.0455446988363106 1.0771936676271474 1.0024315359145894 0.9565910374672335 0.8734673214941938 1.0656483852388883 0.953585489891456 1.0 12.261752828238963 -1.5228787659075365 0.6746372897669307 0.976090929419572 39.58590698755788 0.8174539672440501 0.05208681060118396 102.94704165746754 0.6045156908723891 0.02172764035722414 5967.4309958898875 0.029999998575123612 1.5228787659075365 38.60981605813831 TLEEVVMAEEEDEGTDRPGS(ph)PA ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLEEVVMAEEEDEGTDRPGSPA 22 1 F8WC89;A6NKF1 F8WC89 SAC3D1 SAC3 domain-containing protein 1 1 TLEEVVMAEEEDEGT(0.006)DRPGS(0.994)PA 136.88 4.8027e-11 0.0 3345.8 2963.1 3738.1 3461.4 4270.5 6006.1 4091.4 4103.2 4164.7 3231.7 True False 3912.1778574377945 3257.256985554312 3827.230480823195 3267.4689800102133 3433.726181040757 5691.129542865227 3703.8329728291433 3995.4953476997657 4225.600858661681 3817.5816278768766 1.0247790980735432 0.8532252360418588 1.0025274778346218 0.8559002265073753 0.8994506249629041 1.4907682657804262 0.9702040018693735 1.0466037762031652 1.1068789800865952 1.0 11.898443289850327 TLEGELHDLR ddPTM_PC-9_AZD4547_30min_R2 4 TLEGELHDLR 10 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ;;; 181.53 0.00036148 96076200.0 153633.0 144692.0 185815.0 281979.0 247287.0 209967.0 167323.0 220851.0 159968.0 197619.0 False True 202485.09823508325 191460.85939372334 183350.97169063598 216973.09808212155 212955.46853432825 196837.73029779107 182214.42285239883 186723.55260110382 168423.58189885554 190700.4189605426 1.061796819004257 1.003987618052051 0.9614607701966965 1.1377693833332112 1.1167016291578804 1.0321829987091866 0.9555009047468345 0.9791460009311169 0.8831841210254693 1.0 17.540948487629343 -7.212297077062993 3.8923847000757292 0.9516792065588046 1.0543212185643989 0.4378367258343383 0.054729070974986735 0.24063068948385724 7.663485399933609 0.024169681970138367 0.017736980926472433 6.133423077633234e-08 7.212297077062993 0.10264201200559431 TLEGELHDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TLEGELHDLR 10 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ;;; 184.71 0.0001229 67503600.0 127362.0 124668.0 147288.0 158751.0 181054.0 158198.0 158940.0 151476.0 140861.0 119973.0 False True 148921.8710858368 137044.21513789095 150799.90451285045 149856.69614768613 145577.76840701414 149901.81838833756 143884.05257404875 147499.91550208887 142920.82564216948 141723.1551942545 1.0507942113038289 0.9669853521822153 1.0640456339414317 1.057390346286627 1.0271981893676885 1.0577087292677958 1.015247313516499 1.0407608784881792 1.0084507746548077 1.0 17.112715964201506 -9.850669180084795 6.856041302184909 0.9999999867901477 1.0322082567891258 0.10545331037473638 0.02801398752224821 0.0 0.0 0.02643514159109377 0.006411463636489016 1.4103627204611235e-10 9.850669180084795 0.03220826999897808 TLEGELHDLR ddPTM_PC-9_Lapatinib_30min_R1 4 TLEGELHDLR 10 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ;;; 188.99 0.0001229 88448300.0 235381.0 223242.0 254717.0 221818.0 243142.0 244365.0 206129.0 215566.0 259983.0 196852.0 False True 232024.42377641093 222725.09686494782 233775.15149605426 238131.23568315658 228840.865595564 233914.07859263732 216801.3510230569 225581.9833223731 230700.97679764038 230877.60591119807 1.0049672113529016 0.9646890437291439 1.0125501370018999 1.0314176411494342 0.991178268210138 1.0131518718303374 0.9390315278409666 0.97706307388313 0.9992349664539331 1.0 17.81676871940823 TLENSPISSCDTSDT(ph)EGPVPVNSAAVLKK ddPTM_PC-9_AZD4547_30min_R2 1 TLENSPISSCDTSDTEGPVPVNSAAVLKK 29 1 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 TLENS(0.001)PIS(0.004)S(0.016)CDT(0.078)S(0.38)DT(0.52)EGPVPVNSAAVLKK 112.11 1.0544000000000001e-05 0.0 6272.0 3614.5 8814.7 9490.8 9545.2 6974.9 5955.7 8884.9 6934.1 7918.8 True False 8266.365534295655 4782.816439600072 8697.811318577338 7302.842691398296 8220.013742145247 6538.758400387041 6485.745762280315 7511.94285969069 7300.6223697542855 7641.56522229513 1.081763394517343 0.625894865837913 1.1382237886552993 0.9556736714215861 1.075697648717625 0.8556831238329909 0.848745718136046 0.9830371973759705 0.9553831129326613 1.0 12.899652460509493 -5.715192930450035 0.005824381060055677 1.877755654531263 5.89948248277863e-08 0.0034866356705153256 0.1398961705232918 122455.15376031905 156.45024234138435 24470.747301055584 25976.780832432763 1.9266688220470017e-06 5.715192930450035 -1.8777555955364382 TLEPVKPPTVPNDY(ph)MTSPAR ddPTM_PC-9_Lapatinib_30min_R1 1 TLEPVKPPTVPNDYMTSPAR 20 1 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 TLEPVKPPTVPNDY(0.76)MT(0.17)S(0.07)PAR 67.655 0.0034661 10559000.0 24746.0 22595.0 26984.0 19387.0 23117.0 18738.0 18778.0 15101.0 21640.0 15762.0 True False 24393.117502139394 22542.68266573266 24765.479681252204 20812.78465313612 21757.303509770656 17936.61942041142 19750.232958540342 15802.647588910857 19202.675320697657 18486.440698455186 1.3195140102971685 1.2194171411058286 1.339656458764489 1.1258405548492272 1.176933075688756 0.9702581320540676 1.068363200937364 0.8548236973616776 1.0387437816681673 1.0 14.174179860592782 -6.419243335530749 1.0299828527340027 0.9677474313664386 1.2908330038498892 0.7574946380113939 0.07252156161673673 0.2326295021394932 0.5259595618415144 0.03240088723355209 0.04202291534756473 3.8085237172529504e-07 6.419243335530749 0.3230855724834506 TLEPVKPPTVPNDYMT(ph)SPAR ddPTM_PC-9_AZD4547_30min_R2 3 TLEPVKPPTVPNDYMTSPAR 20 1 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 TLEPVKPPT(0.019)VPNDY(0.129)MT(0.691)S(0.161)PAR;TLEPVKPPT(0.007)VPNDY(0.37)MT(0.444)S(0.179)PAR;TLEPVKPPT(0.001)VPNDY(0.053)MT(0.473)S(0.473)PAR 65.905 0.0040281 47301000.0 49843.0 54085.0 74266.0 98952.0 81867.0 78054.0 71902.0 75763.0 70545.0 74852.0 True False 65692.03720119553 71566.91856017978 73281.1843154577 76140.14519316022 70501.18017728339 73173.27104099144 78301.13870736946 64055.56921054212 74273.86467952818 72231.45426317558 0.9094657981250986 0.9907999124512354 1.0145328660898538 1.0541134187295096 0.9760454208828756 1.013038873264054 1.084031043069948 0.8868099066253797 1.0282759143808884 1.0 16.140339596545587 -4.766777325582869 3.442732070105803 1.006471285469743 0.8955352369833562 0.2600792535005838 0.0491536136518177 0.4438498443547833 8.368803746682593 0.012210602016429031 0.13301185399813525 1.7108923105699162e-05 4.766777325582869 -0.11093604848638683 TLEPVKPPTVPNDYMT(ph)SPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TLEPVKPPTVPNDYMTSPAR 20 1 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 TLEPVKPPT(0.004)VPNDY(0.404)MT(0.462)S(0.129)PAR;TLEPVKPPT(0.001)VPNDY(0.395)MT(0.465)S(0.139)PAR;TLEPVKPPT(0.002)VPNDY(0.126)MT(0.671)S(0.2)PAR 58.123000000000005 0.01149 41705500.0 61269.0 67339.0 61959.0 74319.0 87388.0 87608.0 75823.0 71327.0 72729.0 64005.0 True False 71640.63158208983 74023.97089205298 63436.33754081604 70155.14737544885 70264.94872000694 83013.68225493038 68640.496529018 69454.74182720359 73792.52403524981 75608.59983669882 0.94751961730307 0.9790416837758091 0.8390095528528143 0.9278725902472938 0.9293248237868018 1.0979396845626717 0.9078398049596118 0.918609020365587 0.9759805656318009 1.0 16.20626271764843 -6.555307284490276 24.999999194696215 0.9752677857400679 0.9222234679272091 0.1819096025978325 0.05851666993257465 378.6968662330438 291944.64178298437 0.019935834921002107 0.019935990611950498 2.7841505494928526e-07 6.555307284490276 -0.05304431781285879 TLEPVKPPTVPNDYMT(ph)SPAR ddPTM_PC-9_Lapatinib_30min_R1 4 TLEPVKPPTVPNDYMTSPAR 20 1 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 TLEPVKPPTVPNDY(0.05)MT(0.764)S(0.186)PAR;TLEPVKPPT(0.007)VPNDY(0.415)MT(0.468)S(0.11)PAR;TLEPVKPPT(0.001)VPNDY(0.097)MT(0.451)S(0.451)PAR;TLEPVKPPTVPNDY(0.004)MT(0.498)S(0.498)PAR 94.72 0.00040794 47396800.0 120040.0 110732.0 120493.0 99253.0 111436.0 104754.0 99865.0 98860.0 128355.0 82822.0 True False 118328.20758736017 110475.60685735363 110586.53065643035 106552.39671830201 104881.55357160553 100273.91561350093 105035.5210568021 103453.39650617352 113898.30826192921 97137.6723466218 1.2181495060446066 1.137309595633889 1.1384515192192195 1.0969214532759766 1.0797206792988698 1.0322865803875545 1.0813057233037042 1.0650182777389907 1.1725451671880658 1.0 16.56774329586559 -4.404430039707687 0.6964779550728163 1.072968752509495 1.37746048137159 0.5262288348199632 0.04277755566764125 3.932088651907105 1.0001756009417426 0.017594696032242608 1.0633659763407755 3.9406690258265485e-05 4.404430039707687 0.30449172886209497 TLEPVKPPTVPNDYMTS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 3 TLEPVKPPTVPNDYMTSPAR 20 1 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 TLEPVKPPTVPNDY(0.003)MT(0.193)S(0.804)PAR;TLEPVKPPTVPNDYMT(0.069)S(0.93)PAR;TLEPVKPPTVPNDYMT(0.068)S(0.931)PAR 116.92 8.0714e-06 52681000.0 105275.0 105596.0 128883.0 166209.0 162175.0 136365.0 129185.0 159575.0 127406.0 150514.0 True False 138750.2601439695 139727.84195767308 127173.92720934375 127892.08295345177 139659.80059426816 127838.07499301503 140682.21473549414 134916.35041870357 134140.42105549583 145244.55067289597 0.955287200112917 0.9620177921328902 0.8755848437698092 0.880529302896027 0.9615493314361571 0.8801574613351112 0.9685885913360245 0.9288909621301218 0.9235487351094661 1.0 17.148124511631735 -10.471161427140242 0.4705155532706133 1.024611244306286 0.9226602979128455 0.2903793626058633 0.03458294479276854 22.284285218021157 3.2846036120029067 0.7982540216701488 0.018401431459325667 3.3793920094949014e-11 10.471161427140242 -0.10195094639344049 TLEPVKPPTVPNDYMTS(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLEPVKPPTVPNDYMTSPAR 20 1 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 TLEPVKPPT(0.004)VPNDY(0.106)MT(0.4)S(0.49)PAR 58.457 0.026139999999999997 16233000.0 18241.0 17034.0 20827.0 19082.0 24927.0 18047.0 16305.0 21081.0 17851.0 16470.0 True False 21328.84102382772 18725.022946215824 21323.59466683734 18012.897404678708 20042.733289966738 17100.58355007221 14760.472362022592 20527.646087165806 18112.037104225914 19455.88062355173 1.0962670586089398 0.9624351273798839 1.0959974045597662 0.9258330554759746 1.0301632538649836 0.878941636256321 0.7586638018407015 1.055086967501059 0.9309286716274838 1.0 14.247918661452514 -6.098265231865066 1.4532018161632994 0.9256198528596098 1.0414795300178248 0.2187360125595329 0.08836681292308361 0.6444498099119914 2.738975785572859 0.03222888286575866 0.051731559402445275 7.975074855862791e-07 6.098265231865066 0.11585967715821499 TLEPVKPPTVPNDYMTS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 1 TLEPVKPPTVPNDYMTSPAR 20 1 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 TLEPVKPPTVPNDYMT(0.054)S(0.946)PAR 131.64 1.9235e-05 11869000.0 64000.0 44303.0 49859.0 53004.0 48230.0 48912.0 43049.0 36754.0 48077.0 37857.0 True False 63087.34826383741 44200.419125468194 45759.785481305735 56902.090976160674 45393.20622382834 46820.147779440915 45277.86657962526 38461.725017073644 42662.06198674592 44400.53200871831 1.4208691970503828 0.9954930070835452 1.030613450134348 1.2815632696695527 1.0223572594786727 1.0544951977207726 1.0197595508705768 0.8662446884537657 0.9608457389287354 1.0 15.438289342650537 -6.874385691702594 1.0174703640277343 0.9382153465120714 1.1623641576900496 0.3733524926888807 0.12215143810538741 0.603721490476581 1.32084728487709 0.07295375151586007 0.05920919421554093 1.3354090290848781e-07 6.874385691702594 0.22414881117797825 TLEPVRPPVVPNDYVPS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 2 TLEPVRPPVVPNDYVPSPTR 20 1 H0Y6B5;B7Z836;E7EW77;E7EP65;A0A0C4DG21;F8WAL6;Q9NYB9-3;Q9NYB9-2;Q9NYB9-4;Q9NYB9;H7C3Q7 H0Y6B5 ABI2 Abl interactor 2 1 TLEPVRPPVVPNDYVPS(0.5)PT(0.5)R;TLEPVRPPVVPNDYVPS(0.82)PT(0.179)R 80.061 0.00070771 10645800.0 15102.3 16656.199999999997 21304.0 28507.0 28137.0 21472.5 16219.7 24679.2 17712.1 22799.7 True False 19904.517252645623 22039.990920256383 21021.49504021368 21935.15157875958 24230.663229973292 20129.821180563256 17663.221878277633 20865.596711598173 18648.325446031187 22001.489442688588 0.904689534974196 1.0017499486872508 0.9554578154798253 0.9969848466804119 1.1013192217323038 0.9149299293122487 0.8028193693108071 0.9483720075384311 0.8475937728946935 1.0 14.425313573246859 -6.980083477703313 24.92149977978309 0.8901768864475887 0.9925523165202337 0.30080642030340554 0.0677663630191823 258.1850997046523 323065.4009627711 0.02317598031092615 0.020436861549882984 1.0469272940872222e-07 6.980083477703313 0.10237543007264494 TLEPVRPPVVPNDYVPS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLEPVRPPVVPNDYVPSPTR 20 1 H0Y6B5;B7Z836;E7EW77;E7EP65;A0A0C4DG21;F8WAL6;Q9NYB9-3;Q9NYB9-2;Q9NYB9-4;Q9NYB9;H7C3Q7 H0Y6B5 ABI2 Abl interactor 2 1 T(0.001)LEPVRPPVVPNDY(0.004)VPS(0.79)PT(0.206)R;TLEPVRPPVVPNDY(0.001)VPS(0.824)PT(0.175)R 78.428 0.00084623 9227700.0 20867.2 21060.1 20419.0 21009.1 31978.0 27015.0 24986.0 18808.9 22657.0 15983.599999999999 True False 24399.604814013364 23150.807546647877 20905.86639948874 19832.028239421208 25712.14045599375 25598.285842810496 22619.145197025227 18315.186304676878 22988.315762167193 18881.300153892007 1.2922629593907424 1.2261235909581043 1.1072259976323404 1.0503528929565387 1.3617780685878087 1.3557480488192926 1.1979654479653372 0.9700172210281591 1.2175176272185158 1.0 14.20467049069996 -7.603683536303538 8.058881096394783 1.07136731672915 1.2282376869617069 0.3225208507145295 0.11010499259493692 0.34735430956577473 30.34771562179714 0.05523851224141694 0.03174945816323166 2.4906715711855903e-08 7.603683536303538 0.1568703702325569 TLEPVRPPVVPNDYVPS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 1 TLEPVRPPVVPNDYVPSPTR 20 1 H0Y6B5;B7Z836;E7EW77;E7EP65;A0A0C4DG21;F8WAL6;Q9NYB9-3;Q9NYB9-2;Q9NYB9-4;Q9NYB9;H7C3Q7 H0Y6B5 ABI2 Abl interactor 2 1 TLEPVRPPVVPNDYVPS(0.883)PT(0.117)R 84.32700000000001 0.00037539999999999996 5626300.0 13717.0 11600.0 14855.0 10107.0 11241.0 12190.0 10812.0 10901.0 9571.5 10721.0 True False 13521.393064610276 11573.14091270187 13633.679241958258 10850.302495963624 10579.826480656313 11668.662116277903 11371.792456477693 11407.500256057032 8493.456877636674 12574.110565165467 1.0753359447998734 0.9203943971006092 1.0842658946970098 0.8629081508176512 0.8413976023056459 0.9279910539838927 0.9043814588350606 0.9072212461420261 0.6754717825661894 1.0 13.618168733567755 -5.776575299213376 24.905323536570005 0.8724626901218755 1.0160383079562176 0.380918251915941 0.08874506413404627 232.5924116776944 382717.41902886814 0.02407321933265131 0.03586138073547467 1.6727255893311317e-06 5.776575299213376 0.14357561783434214 TLEPVRPPVVPNDYVPSPT(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 TLEPVRPPVVPNDYVPSPTR 20 1 H0Y6B5;B7Z836;E7EW77;E7EP65;A0A0C4DG21;F8WAL6;Q9NYB9-3;Q9NYB9-2;Q9NYB9-4;Q9NYB9;H7C3Q7 H0Y6B5 ABI2 Abl interactor 2 1 TLEPVRPPVVPNDY(0.001)VPS(0.266)PT(0.733)R 77.062 0.0014699000000000001 5869600.0 30431.0 19727.0 23737.0 20022.0 23118.0 20666.0 21411.0 12791.0 20618.0 21799.0 True False 29997.048359638084 19681.323343523276 21785.435487469764 21494.484671434016 21758.244691736745 19782.163354798937 22519.55681517241 13385.316555841242 18295.78372283476 25566.92810465831 1.1732754219374757 0.7697961703869042 0.8520943696595464 0.8407144019589006 0.8510308552779315 0.773740328670718 0.8808080784280585 0.523540274414212 0.7156035190438564 1.0 14.641991209100137 -4.759413779653991 24.997579803948724 0.7919972405877117 1.173275907251666 0.4711604950089222 0.11804823986755389 47.46775850189976 585643.0883049847 0.029683603213508613 0.18898267973236033 1.7401481348057585e-05 4.759413779653991 0.3812786666639544 TLETVPLER ddPTM_PC-9_Lapatinib_30min_R1 3 TLETVPLER 9 0 P22626;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;; 110.87 0.010472 21292400.0 88569.0 111715.0 107325.0 111699.0 116189.0 105934.0 108053.0 92049.0 99233.0 86476.0 False True 87305.98981843458 111456.33078124908 98501.15278648051 119913.71707694084 109354.99145636303 101403.44976421527 113647.45563261051 96325.9325813957 88056.33457018451 101423.26137797313 0.8608083454649733 1.098922764531164 0.9711889703427814 1.1823098118493696 1.0782042498991509 0.9998046640042068 1.1205265349245828 0.9497420145307567 0.8682064979356735 1.0 16.630029046166356 -7.9103414658349065 7.274278254765087 0.9259652766921441 1.048423919506928 0.22673657423917382 0.08884625765010448 0.28863992657519066 19.67665843638658 0.04729262761939821 0.022535017881201224 1.2293018470702243e-08 7.9103414658349065 0.12245864281478391 TLEVVS(ph)PSQSVTGSAGHTPY(ph)YQSPTDEK ddPTM_PC-9_AZD4547_30min_R2 1 TLEVVSPSQSVTGSAGHTPYYQSPTDEK 28 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 T(0.001)LEVVS(0.334)PS(0.034)QS(0.034)VT(0.123)GS(0.482)AGHT(0.265)PY(0.448)Y(0.226)QS(0.047)PT(0.007)DEK 72.946 0.00067963 8356500.0 9843.7 10121.0 28668.0 32873.0 33977.0 35964.0 21846.0 41639.0 26135.0 34168.0 True False 12973.791838320496 13392.415323057772 28287.843588661573 25294.637732787163 29259.880035711067 33715.165394703814 23790.251678690303 35204.64931903125 27516.44274434003 32971.788719929806 0.3934815896256937 0.4061780037721376 0.8579408241677522 0.7671600090503374 0.887421676884182 1.0225458400540057 0.721533547384109 1.0677203356502096 0.8345450402485356 1.0 15.008944534903907 -5.2738800257371015 3.8850984800761066 0.8949590534682256 0.38596614399953433 0.7849655601486438 0.10377449775044922 0.08773390135622908 3.0517180507611315 0.02659490221245829 0.06846539012539431 5.322552749842242e-06 5.2738800257371015 -0.5089929094686912 down TLEVVS(ph)PSQSVTGSAGHTPYY(ph)QSPTDEK ddPTM_PC-9_Lapatinib_30min_R1 1 TLEVVSPSQSVTGSAGHTPYYQSPTDEK 28 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 T(0.001)LEVVS(0.728)PS(0.066)QS(0.072)VT(0.103)GS(0.031)AGHT(0.012)PY(0.137)Y(0.457)QS(0.334)PT(0.059)DEK 98.289 4.0298e-05 0.0 21682.0 21644.0 39031.0 25111.0 31067.0 35536.0 30817.0 34801.0 38315.0 22628.0 True False 21372.81070400817 21593.884647803403 35822.02184401703 26957.74670784035 29239.70014007202 34016.20811846199 32412.55347126093 36417.98150729662 33999.561225163154 26539.21965008527 0.805329281938382 0.8136593664966341 1.3497767574300903 1.0157701342870393 1.1017543290869922 1.2817335463121915 1.221307706052193 1.3722325670257458 1.2811062899904788 1.0 14.695838330381768 -5.2479801931801795 24.423398692450693 1.2094229350907364 0.8094941995778738 0.62298666186682 0.12235250834464459 366.3711003128263 664822.6648335644 0.03174543929436653 0.0829037697079764 5.649627404172129e-06 5.2479801931801795 -0.39992873551286257 TLEVVS(ph)PSQSVTGSAGHTPYYQS(ph)PTDEK ddPTM_PC-9_AZD4547_30min_R2 1 TLEVVSPSQSVTGSAGHTPYYQSPTDEK 28 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 T(0.001)LEVVS(0.371)PS(0.086)QS(0.086)VT(0.086)GS(0.371)AGHT(0.022)PY(0.324)Y(0.239)QS(0.378)PT(0.037)DEK 73.435 0.00011414 7617000.0 13907.0 20123.0 38740.0 45007.0 48495.0 48141.0 32149.0 52637.0 39827.0 47500.0 True False 18329.136716430112 26627.36622328738 38226.28228773367 34631.33150121838 41762.30633463246 45130.735659727405 35010.19871913459 44503.161127929285 41932.17391156804 45837.039457874795 0.39987610310816374 0.5809137443913343 0.8339605423876564 0.7555315943353039 0.9111039200734791 0.9845909813002539 0.7637971198229262 0.9708995531622112 0.9148098220895046 1.0 15.484226245254801 -4.661365942393217 0.7796704210304597 0.9197793303786387 3.38253260345083e-18 0.8460520794641234 0.07234920239212098 1.132997964626326 0.46364899190961734 0.02750997963366614 0.949368348228576 2.180891488802295e-05 4.661365942393217 -0.9197793303786387 down TLEVVSPS(ph)QSVTGSAGHTPYYQSPTDEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLEVVSPSQSVTGSAGHTPYYQSPTDEK 28 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.001)LEVVS(0.092)PS(0.184)QS(0.184)VT(0.184)GS(0.184)AGHT(0.159)PY(0.01)Y(0.003)QSPTDEK 77.169 0.00021659999999999998 0.0 2300.0 4187.0 14845.0 12336.0 19128.0 12889.0 15110.0 7800.5 14211.0 7182.7 True False 2689.344572929322 4602.657689080998 15198.96109997601 11644.853913851617 15380.005711496917 12213.078150212263 13678.671413073373 7595.745140312933 14418.808990429354 8484.866651778084 0.3169577888847251 0.5424549233329987 1.7913022942783579 1.3724262727701593 1.812639649236431 1.4393954143820158 1.6121256791003165 0.8952109033700809 1.699355992519665 1.0 13.050676271203132 -5.1649268341380115 5.371453039303768 1.4627961042064928 0.3821400873620897 0.6601099883598143 0.2945750800677621 0.1215930454630272 5.307725183052117 0.07219858638553643 0.20140540916499342 6.840268760088685e-06 5.1649268341380115 -1.080656016844403 TLEVVSPSQSVTGS(ph)AGHTPY(ph)YQSPTDEK ddPTM_PC-9_Lapatinib_30min_R1 1 TLEVVSPSQSVTGSAGHTPYYQSPTDEK 28 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 TLEVVS(0.111)PS(0.11)QS(0.11)VT(0.11)GS(0.557)AGHT(0.195)PY(0.295)Y(0.295)QS(0.173)PT(0.043)DEK 93.21 3.6932e-07 7742100.0 21470.0 17131.0 38147.0 24730.0 34488.0 40236.0 30861.0 34494.0 43616.0 28303.0 True False 21163.833862884196 17091.33422202551 35010.700911678345 26548.726696861635 32459.4836460168 38515.20007469708 32458.831575967302 36096.717166538045 38703.50678315849 33195.13583862307 0.637558284616499 0.5148746582967577 1.0546937081951275 0.7997776188031671 0.9778385545345374 1.160266379445992 0.977818910992403 1.0874098344414345 1.165939099370286 1.0 15.01868423510909 -5.18494191575673 0.7264892861977312 1.079392024695712 0.39009578437502784 0.676915331038024 0.11823927500555909 1.0212899394274748 0.5933967938990348 0.05118673222822267 0.5263824853073102 6.532179107247566e-06 5.18494191575673 -0.6892962403206842 TLEVVSPSQSVTGS(ph)AGHTPYYQS(ph)PTDEK ddPTM_PC-9_AZD4547_30min_R2 1 TLEVVSPSQSVTGSAGHTPYYQSPTDEK 28 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 TLEVVS(0.03)PS(0.083)QS(0.083)VT(0.083)GS(0.733)AGHT(0.134)PY(0.11)Y(0.243)QS(0.362)PT(0.139)DEK 54.56 0.0077515 14667000.0 25140.0 22488.0 35046.0 42576.0 37888.0 53365.0 37950.0 60336.0 32497.0 37721.0 True False 33133.997055515436 29756.8062231917 34581.26714135039 32760.760992642765 32627.9051944851 50028.07811390192 41327.47648110854 51012.457583349 34214.72507605959 36400.39927137882 0.9102646596947712 0.8174857094655307 0.9500243907637907 0.9000110341757197 0.8963611896460713 1.3743826747867125 1.1353577792649057 1.4014257701689405 0.9399546642600211 1.0 15.151666654799767 -6.736267752783781 24.68059922473993 1.193134098779891 0.8938865976183387 0.49562799326428764 0.1379404300061481 145.86545640721113 143019.56120080664 0.042503974579752565 0.042486720957487525 1.8354064231387392e-07 6.736267752783781 -0.2992475011615524 TLEVVSPSQSVTGS(ph)AGHTPYYQSPTDEK ddPTM_PC-9_AZD4547_30min_R2 1 TLEVVSPSQSVTGSAGHTPYYQSPTDEK 28 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TLEVVS(0.004)PS(0.038)QS(0.038)VT(0.011)GS(0.375)AGHT(0.189)PY(0.143)Y(0.199)QS(0.003)PTDEK 82.831 2.3577000000000003e-06 124210000.0 19519.0 16699.0 84125.0 110350.0 106570.0 99346.0 55754.0 114190.0 79615.0 87918.0 True False 25725.635979578605 22096.625183256783 83009.44753370144 84910.51239050478 91774.59503210205 93133.87891508873 60715.99799019033 96544.5593251564 83823.2863627561 84840.01758015662 0.3032252551724555 0.2604505021746365 0.9784232712502015 1.0008309146126892 1.0817371053158218 1.0977588356472945 0.7156528218871008 1.1379601522823986 0.9880159004394369 1.0 16.372457299366552 -5.267861043516873 8.546278668556802 1.00162703184291 0.2807721628342773 0.8752483286955418 0.10846054761983812 0.036740504911601995 31.243607563718104 0.028008437119184642 0.06366392414711984 5.396832714815452e-06 5.267861043516873 -0.7208548690086326 TLEVVSPSQSVTGS(ph)AGHTPYYQSPTDEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLEVVSPSQSVTGSAGHTPYYQSPTDEK 28 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TLEVVS(0.001)PS(0.01)QS(0.01)VT(0.053)GS(0.653)AGHT(0.235)PY(0.027)Y(0.01)QS(0.001)PTDEK;TLEVVS(0.003)PS(0.053)QS(0.053)VT(0.044)GS(0.202)AGHT(0.165)PY(0.122)Y(0.149)QS(0.165)PT(0.044)DEK 107.95 1.2787e-10 123431000.0 32720.1 61490.0 145340.0 136610.0 187786.0 159869.0 155756.0 118861.0 147431.0 101473.0 True False 38258.96667856729 67594.32082674722 148805.45680501946 128956.18459559557 150990.68133308014 151485.18820671 141001.66410421277 115741.02469363956 149586.89946295085 119869.25164017409 0.3191724829768173 0.5639004156766841 1.2413980630471162 1.075807038344569 1.2596281303759782 1.2637535158844677 1.176295523454792 0.9655605846366112 1.2479171882375957 1.0 16.87110210653894 -5.138704088431928 3.524365133465943 1.1589485628138456 0.35918901020137917 0.8791452521218981 0.10698916916266772 0.07246454711954836 1.6037679884852418 0.027853880505760528 0.09171798471220445 7.266008667139555e-06 5.138704088431928 -0.7997595526124665 down TLEVVSPSQSVTGS(ph)AGHTPYYQSPTDEK ddPTM_PC-9_Lapatinib_30min_R1 1 TLEVVSPSQSVTGSAGHTPYYQSPTDEK 28 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TLEVVS(0.002)PS(0.162)QS(0.162)VT(0.124)GS(0.532)AGHT(0.006)PY(0.002)Y(0.008)QS(0.002)PT(0.001)DEK 77.63 1.2073e-05 87948000.0 25348.0 16907.0 45368.0 23687.0 50398.0 52823.0 33840.0 39573.0 62798.0 29286.0 True False 24986.5328717461 16867.852880262977 41638.01816554444 25429.02099751563 47433.688726280314 50563.883426427186 35592.06961960832 41411.70604833911 55725.02794774363 34348.0460788579 0.7274513611161699 0.491086242330552 1.2122383343131038 0.7403338442930482 1.3809719661310504 1.472103633212212 1.0362181749114443 1.2056495427211236 1.6223638404294505 1.0 15.067940411852833 -5.601958780871939 1.017740057687772 1.2856606108242226 0.5712354655545966 0.4756387402762726 0.24724285939760485 0.6013813659773721 1.0857704397257224 0.09093682172795112 0.3518665878579238 2.500582682111374e-06 5.601958780871939 -0.714425145269626 TLEVVSPSQSVTGSAGHT(ph)PYYQSPTDEK ddPTM_PC-9_AZD4547_30min_R2 1 TLEVVSPSQSVTGSAGHTPYYQSPTDEK 28 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TLEVVSPS(0.001)QS(0.001)VT(0.006)GS(0.191)AGHT(0.769)PY(0.024)Y(0.009)QSPTDEK 135.37 6.8714e-10 124030000.0 12799.0 14149.0 71059.0 102160.0 70133.0 84518.0 45659.0 97679.0 51454.0 73341.0 True False 16868.815764261828 18722.387551224638 70116.71123087415 78608.59035626605 60396.24353369993 79233.07609914287 49722.562546796704 82584.95499012123 54173.75339457706 70773.3539132629 0.23834981432327768 0.26454006368230165 0.9907218939603526 1.1107088474654703 0.8533754611618273 1.1195325884406706 0.702560494840117 1.1668933351856432 0.7654540925242901 1.0 16.110918669052573 -5.2595769113502335 23.89726713832385 0.9671718387981338 0.25144477776349844 0.7949324309156036 0.1446856725429527 32.04667019273201 411172.79694217537 0.03420250361880664 0.08144319081029244 5.5007649612652e-06 5.2595769113502335 -0.7157270610346353 TLEVVSPSQSVTGSAGHT(ph)PYYQSPTDEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLEVVSPSQSVTGSAGHTPYYQSPTDEK 28 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TLEVVSPS(0.003)QS(0.003)VT(0.002)GS(0.008)AGHT(0.613)PY(0.141)Y(0.205)QS(0.019)PT(0.006)DEK;TLEVVS(0.002)PS(0.014)QS(0.014)VT(0.035)GS(0.115)AGHT(0.238)PY(0.166)Y(0.235)QS(0.13)PT(0.051)DEK 106.62 5.7992e-10 119352000.0 18270.1 25252.3 88170.0 81510.0 89311.0 88880.0 83798.0 60633.0 78553.0 46777.0 True False 21362.867079076514 27759.18145736328 90272.307186587 76943.2589589855 71811.15067437789 84218.97633570222 75860.04679501784 59041.44799597384 79701.68901732436 55257.29981347176 0.3866071478553904 0.5023622498940054 1.6336720667009241 1.3924541955310434 1.2995776289609846 1.524123991219158 1.3728511355258644 1.068482321707285 1.442373935866715 1.0 15.753877445122013 -5.2431232769822165 18.642298998115123 1.3520743276145333 0.44447402101165995 0.7944820726935035 0.1824694264314884 12.29767431632923 12514.388020300252 0.04518209304316853 0.11815495841650356 5.713164422006733e-06 5.2431232769822165 -0.9076003066028733 TLEVVSPSQSVTGSAGHT(ph)PYYQSPTDEK ddPTM_PC-9_Lapatinib_30min_R1 1 TLEVVSPSQSVTGSAGHTPYYQSPTDEK 28 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TLEVVSPS(0.002)QS(0.002)VT(0.006)GS(0.331)AGHT(0.638)PY(0.009)Y(0.011)QSPTDEK 83.20200000000001 6.1549e-06 78900000.0 15833.0 14806.0 46135.0 18846.0 39230.0 48383.0 28425.0 35851.0 54233.0 24465.0 True False 15607.218516583394 14771.717616677934 42341.95838625001 20231.997708413033 36922.56852914752 46313.77187628171 29896.70741540681 37516.768340510076 48124.70844119205 28693.742652436624 0.5439241128503693 0.5148062347810715 1.4756512909149688 0.7051013858136407 1.2867811974333754 1.6140721842136136 1.0419242891225984 1.3074895385710241 1.6771847794175914 1.0 14.808448537058396 -4.863743904508014 0.7610290199364872 1.3239177317092639 1.676846062106778e-19 0.45209659753614195 0.2992725331498602 2.2233401936606536 1.0620530532043015 0.11908434565997675 2.4676106929767334 1.3685355880463408e-05 4.863743904508014 -1.3239177317092639 TLEVVSPSQSVTGSAGHTPYYQS(ph)PTDEK ddPTM_PC-9_AZD4547_30min_R2 1 TLEVVSPSQSVTGSAGHTPYYQSPTDEK 28 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TLEVVSPSQSVTGS(0.001)AGHT(0.038)PY(0.022)Y(0.201)QS(0.643)PT(0.096)DEK 91.691 6.6307e-08 42658000.0 18601.0 13448.0 69205.0 108360.0 84463.0 100640.0 53685.0 127120.0 82961.0 72133.0 True False 24515.731075164786 17794.803010026775 68287.29648225628 83379.27614531116 72736.77038750531 94346.96489052917 58462.86099837448 107476.52492699769 87346.1490917618 69607.64562557655 0.35219882607488673 0.2556443742652355 0.981031550033706 1.1978465209671505 1.0449537508962807 1.3554109472115579 0.8398913721755439 1.5440333308372471 1.2548355616220905 1.0 16.08695815832896 -5.3577511581567485 3.2798568556067402 1.1839714646225732 0.29046659302272787 0.7718646111251845 0.18652665246439068 0.10471004406332204 2.1165969936836997 0.04925821543475156 0.12079220896867775 4.38782038882946e-06 5.3577511581567485 -0.8935048715998453 down TLEVVSPSQSVTGSAGHTPYYQS(ph)PTDEK ddPTM_PC-9_Lapatinib_30min_R1 2 TLEVVSPSQSVTGSAGHTPYYQSPTDEK 28 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TLEVVSPSQSVTGS(0.001)AGHT(0.078)PY(0.205)Y(0.31)QS(0.319)PT(0.087)DEK;TLEVVSPSQSVTGSAGHT(0.011)PY(0.154)Y(0.154)QS(0.503)PT(0.178)DEK 104.38 2.0554e-10 91333000.0 54688.0 43435.0 152378.0 60492.0 133647.0 164705.0 96404.0 132648.0 189073.0 94756.0 True False 53908.139091449106 43334.42892613847 139850.06903608976 64940.78347539642 125786.14622011152 157660.95109610766 101395.32741160529 138811.31033533203 167777.60771304372 111134.44834556675 0.48507136980447835 0.3899279617728639 1.258386316016374 0.5843443184553043 1.1318375903480988 1.4186505934313831 0.912366317744448 1.2490394508794027 1.5096813833218303 1.0 16.761946552676008 -5.017272031274555 0.5944166790707878 1.235700058950293 1.948366030225778e-19 0.5092671242096707 0.26198344316124916 2.3723036722724173 0.7722551398548463 0.1388913335051922 1.9371242781779312 9.610101369441317e-06 5.017272031274555 -1.235700058950293 TLFLGIPDENFEDHSAPPS(ph)PEEK ddPTM_PC-9_AZD4547_30min_R2 1 TLFLGIPDENFEDHSAPPSPEEK 23 0 Q99683-2;Q99683 Q99683-2 MAP3K5 Mitogen-activated protein kinase kinase kinase 5 1 TLFLGIPDENFEDHS(0.016)APPS(0.984)PEEK 55.26 0.0054371 2072100.0 13873.0 16306.0 17261.0 22288.0 20101.0 20093.0 16189.0 24325.0 15382.0 17799.0 True False 18284.32542367405 21576.595618790634 17032.107861862944 17149.84594616738 17310.323118516295 18836.581533638724 17629.789637751404 20566.130182891873 16195.061117024612 17175.862427593962 1.064536089570634 1.2562161410961614 0.9916304309994898 0.99848528820394 1.0078284680893994 1.096689124813711 1.0264282048177205 1.1973855909471691 0.9428965319963416 1.0 14.068094920442913 -5.2760064053697615 24.976599428677968 1.0396731281502367 1.1603761286698266 0.2909790013004526 0.0791381025041085 864.2876166392548 1481906.053203328 0.019974764671546543 0.04185324160977494 5.2965563199137e-06 5.2760064053697615 0.12070300051958993 TLFLGIPDENFEDHSAPPS(ph)PEEK ddPTM_PC-9_Lapatinib_30min_R1 1 TLFLGIPDENFEDHSAPPSPEEK 23 0 Q99683-2;Q99683 Q99683-2 MAP3K5 Mitogen-activated protein kinase kinase kinase 5 1 TLFLGIPDENFEDHS(0.087)APPS(0.913)PEEK 60.45399999999999 0.0029008000000000003 2441000.0 12739.0 13699.0 16968.0 15389.0 19725.0 15652.0 16085.0 14941.0 18433.0 13455.0 True False 12557.339523953508 13667.280807164047 15572.956538374136 16520.75839619909 18564.81428084208 14982.600446594071 16917.802595490546 15635.213404802129 16356.881431904803 15780.67882233946 0.7957414041135591 0.8660768627909946 0.9868369234109708 1.046897828806449 1.176426850191092 0.9494268665670065 1.0720579758293636 0.9907820557546988 1.0365131700639936 1.0 13.945871645265774 -5.2243050633290675 2.0815052771067166 1.0413895724211746 0.7979478888131457 0.6815750625605592 0.05690576272453304 0.20721171875033434 1.610449602679929 0.01590380242202052 0.06603791265632039 5.9661605579407035e-06 5.2243050633290675 -0.24344168360802887 TLFPLIEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLFPLIEAK 9 0 P13010 P13010 XRCC5 X-ray repair cross-complementing protein 5 0 ; 115.71 0.0090405 3386900.0 40788.0 45437.0 40938.0 51723.0 52868.0 45164.0 45982.0 41764.0 34838.0 38042.0 False True 47692.60280027881 49947.6850773282 41914.117178229564 48825.127998228505 42508.89491611349 42795.52033332196 41626.25207914887 40667.739252615786 35347.439842979235 44938.713459693696 1.061281000913725 1.1114622834524877 0.932695085181356 1.0864825501072835 0.9459303937181123 0.9523085339705152 0.9262893588728163 0.9049600249257553 0.7865699109228608 1.0 15.455671202067085 -6.465692014149035 0.7634988230453941 0.88859027161187 1.06845334666877 0.47156394805195667 0.06697169478107118 0.5754635542805427 0.7442887736276014 0.040254733679127755 0.05482198446972791 3.4222204790959715e-07 6.465692014149035 0.17986307505690002 TLFPLIEAK ddPTM_PC-9_Lapatinib_30min_R1 2 TLFPLIEAK 9 0 P13010 P13010 XRCC5 X-ray repair cross-complementing protein 5 0 ; 141.48 0.0032968000000000003 10575800.0 42683.0 44047.0 45819.0 42788.0 43202.0 37723.0 42342.0 39265.0 39125.0 41586.0 False True 42074.33259289645 43945.01187773964 42051.938686454785 45934.7722565837 40660.94329839997 36109.67522660797 44534.26157900286 41089.39524392984 34718.33049548502 48774.084690138116 0.8626370512167433 0.9009910110445417 0.8621779158668145 0.941786453777809 0.8336587668783341 0.7403455227507154 0.9130722157459056 0.8424431848382368 0.7118192112891643 1.0 15.57382717856747 -6.394286488750693 10.501450732492476 0.8307362991314382 0.8903785084348145 0.0862015171149143 0.07886638925071465 0.9416658955634989 75.1405665715983 0.023502085834135624 0.0266445274035664 4.033792101451486e-07 6.394286488750693 0.05964220930337627 TLGDFAAEYAK ddPTM_PC-9_Lapatinib_30min_R1 1 TLGDFAAEYAK 11 0 P09874 P09874 PARP1 Poly [ADP-ribose] polymerase 1 0 88.49600000000001 0.040514999999999995 0.0 17596.0 23570.0 23580.0 23271.0 22707.0 23503.0 18572.0 22555.0 19784.0 16933.0 False True 17345.0778132888 23515.425113136476 21641.34342143224 24982.42696978029 21371.418903679638 22497.83147816896 19533.56728650608 23602.9876410757 17555.7175852441 19859.846488195748 0.873374213823774 1.1840688258649694 1.0897034594046522 1.2579365598132537 1.076111988900938 1.1328300796051556 0.9835709101838426 1.188477849267606 0.883980528030709 1.0 14.277566850775521 -8.267499725614813 24.96240062110143 0.9419902589282465 1.1027481164256399 0.2555089657523576 0.10647841799806801 674.9144978154992 2779911.384189051 0.08880770347478013 0.025305723384295004 5.401324560176418e-09 8.267499725614813 0.16075785749739335 TLGFS(ph)VAQAT(ph)S(ph)SLIS(ph)AGK ddPTM_PC-9_Lapatinib_30min_R1 1 TLGFSVAQATSSLISAGK 18 0 Q8NE22-2;Q8NE22 Q8NE22-2 SETD9 SET domain-containing protein 9 4 T(0.306)LGFS(0.698)VAQAT(0.983)S(0.983)S(0.03)LIS(1)AGK 66.264 0.021144999999999997 0.0 6973.4 6830.7 7048.5 6544.9 10202.0 9367.2 8067.9 6931.4 8733.7 8876.2 True False 6873.958037235062 6814.883933826959 6468.999537996825 7026.233779146368 9601.938417903717 8966.586692009716 8485.61638546212 7253.458148319759 7750.018736061796 10410.439343206948 0.6602947109739876 0.6546202046961475 0.621395440166317 0.6749219266842131 0.9223374827277778 0.8613072317510423 0.8151064624375514 0.6967485145622415 0.7444468461476471 1.0 13.34574333434346 -6.120636349842548 6.3671800972472825 0.8242093025863731 0.6467676203018835 0.5590004993696844 0.0809874575566331 0.20338612872945291 9.789769314404879 0.024907286459476995 0.032382086580923355 7.57466883413216e-07 6.120636349842548 -0.17744168228448964 TLGTPTQPGS(ph)TPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLGTPTQPGSTPR 13 0 Q8NFH5-2;Q8NFH5;Q8NFH5-3 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 TLGT(0.004)PT(0.01)QPGS(0.493)T(0.493)PR;TLGT(0.095)PT(0.11)QPGS(0.398)T(0.398)PR 115.83 0.00028343 12033400.0 36919.0 38389.0 54370.0 52154.0 57012.0 49338.0 51735.0 57323.0 48255.0 45239.0 True False 43168.657516512 42200.006215937494 55666.38699937321 49231.98046554935 45840.90786406641 46750.62842541489 46834.28627103577 55818.33198873896 48960.638085508996 53440.472588273034 0.8077895914038927 0.7896637917307239 1.041652221683171 0.9212489725690188 0.857793833846554 0.8748168974028467 0.87638233725712 1.0444954785259088 0.9161715028742636 1.0 15.705645145552717 -5.22956288874386 24.706009504439244 0.9347293361153468 0.7987266093013303 0.43838201412802835 0.06429984892797395 575.0464411658551 445690.0966099134 0.016977615209191468 0.04490858770645313 5.8943661652330855e-06 5.22956288874386 -0.13600272681401648 TLGTPTQPGST(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 TLGTPTQPGSTPR 13 0 Q8NFH5-2;Q8NFH5;Q8NFH5-3 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 TLGTPTQPGS(0.03)T(0.97)PR 170.26 0.00058837 9384000.0 27335.0 23460.0 27676.0 45352.0 38406.0 43643.0 33043.0 34336.0 33033.0 38018.0 True False 36026.961396679166 31042.986214695728 27308.998156822847 34896.79708141523 33073.98983581597 40913.99631078463 35983.762987227106 29030.160162786255 34779.056941793926 36687.00139177859 0.9820088867975092 0.8461576317777865 0.7443780391095873 0.9512033079169959 0.901517937719154 1.1152177817387192 0.9808314013717927 0.7912928029406022 0.9479939930328504 1.0 15.162981370426406 -5.923207215657806 24.999229133942936 0.952305975053242 0.8549464717497788 0.1879921094805903 0.09305880857920983 63.93037702586602 20809.128649416933 0.027670248198285192 0.041041608024879064 1.1934185507953356e-06 5.923207215657806 -0.09735950330346321 TLGTPTQPGST(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLGTPTQPGSTPR 13 0 Q8NFH5-2;Q8NFH5;Q8NFH5-3 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 TLGTPT(0.012)QPGS(0.077)T(0.911)PR 93.243 0.012201 0.0 17213.0 16994.0 17285.0 16399.0 26788.0 21270.0 20324.0 27916.0 20942.0 12926.0 True False 20126.82092775324 18681.052010566615 17697.139953727543 15480.21719627534 21539.083699267005 20154.56375630498 18398.763586982346 27183.234579446926 21248.237131628415 15269.381477840298 1.3181163203606057 1.2234321368994223 1.1589952074621053 1.0138077445206943 1.4106061683327265 1.3199332131137274 1.204944916313969 1.7802446431046743 1.391558470293308 1.0 13.898354003116737 -6.290884622716917 24.64218727600259 1.3813492758552373 1.1803915061788677 0.14502937403697802 0.1973382900357978 1000.6785271602047 837446.64414631 0.061405744500347484 0.06963848680008643 5.118177900714673e-07 6.290884622716917 -0.20095776967636958 TLHCEGT(ph)EINSDDEQESKEVEETATAK ddPTM_PC-9_Lapatinib_30min_R1 1 TLHCEGTEINSDDEQESKEVEETATAK 27 1 Q9BPX3;H0Y9Z8 Q9BPX3 NCAPG Condensin complex subunit 3 1 T(0.001)LHCEGT(0.693)EINS(0.305)DDEQESKEVEETATAK 84.94200000000001 6.563e-07 20651000.0 15567.0 20140.0 20229.0 20384.0 23357.0 20995.0 16747.0 20645.0 20842.0 15699.0 True False 15345.01172536183 20093.367067397918 18565.84970619817 21883.10735903062 21983.187181628804 20097.09279173539 17614.077716299667 21604.242068277905 18494.55448401019 18412.551232397414 0.8333995398943869 1.09128641728057 1.0083257595248953 1.188488606648201 1.1939240197712935 1.0914887642715136 0.9566342813649414 1.173343215483611 1.0044536604720202 1.0 14.168401919073865 -4.76064189742698 24.999999998955442 1.085501228362644 0.8333992473371983 0.4464994648468067 0.08160229766344308 18.043505816721908 565290.142287619 0.02031691674741194 0.11885794142691301 1.7352342156034153e-05 4.76064189742698 -0.2521019810254457 TLHCEGTEINS(ph)DDEQESK ddPTM_PC-9_AZD4547_30min_R2 2 TLHCEGTEINSDDEQESK 18 0 Q9BPX3;H0Y9Z8 Q9BPX3 NCAPG Condensin complex subunit 3 1 TLHCEGTEINS(0.919)DDEQES(0.081)K;TLHCEGTEINS(1)DDEQESK 165.03 8.4125e-08 34303000.0 70979.0 88508.0 82294.0 70233.0 81315.0 102500.0 107184.0 108393.0 98483.0 80123.0 True False 93548.84554508487 117116.48013172596 81202.72779005567 54041.86693903322 70025.81584906967 96090.65879649488 116723.16835707847 91643.35247334851 103688.61032297062 77317.918157543 1.2099245268667185 1.514739182359895 1.0502446227871394 0.6989565708289961 0.9056867737486808 1.2427993547459535 1.5096522402380692 1.1852796176769271 1.3410683162949977 1.0 16.23851517198448 -6.975205203492847 22.327587413895234 1.2889808504284634 1.077553735848822 0.12795549917732718 0.22977072020385725 140.97865153627046 126948.41003700944 0.08920186528040543 0.07866162118741403 1.0587533476002832e-07 6.975205203492847 -0.21142711457964136 TLHCEGTEINS(ph)DDEQESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLHCEGTEINSDDEQESK 18 0 Q9BPX3;H0Y9Z8 Q9BPX3 NCAPG Condensin complex subunit 3 1 TLHCEGTEINS(0.999)DDEQES(0.001)K 86.439 0.0045776 0.0 10542.0 11814.0 16460.0 9102.5 11669.0 8697.4 9397.3 10032.0 9209.3 8803.2 True False 12326.552386009089 12986.81584399401 16852.468824897613 8592.51643570317 9382.543216617396 8241.293033102347 8507.11971343973 9768.670629782626 9343.9685902161 10399.150473907142 1.1853422466515948 1.2488343039731626 1.6205620706405497 0.8262709975457073 0.902241316745964 0.7924967576708167 0.8180591034609249 0.9393719856533979 0.8985319150503077 1.0 13.344178056267646 -5.780300608186263 24.998555753850024 0.8742951263760714 1.3413050409281404 0.7616234929959982 0.12017689624799975 106.43874882438632 141072.91196984568 0.0338077217006923 0.050238190064709747 1.6584385787975138e-06 5.780300608186263 0.46700991455206897 TLHCEGTEINS(ph)DDEQESK ddPTM_PC-9_Lapatinib_30min_R1 5 TLHCEGTEINSDDEQESK 18 0 Q9BPX3;H0Y9Z8 Q9BPX3 NCAPG Condensin complex subunit 3 1 TLHCEGTEINS(1)DDEQESK;TLHCEGTEINS(1)DDEQESK;T(0.002)LHCEGT(0.002)EINS(0.993)DDEQES(0.003)K;TLHCEGTEINS(1)DDEQESK;TLHCEGTEINS(1)DDEQESK 164.89 8.5282e-08 120698000.0 137515.6 217133.0 163526.0 170628.0 213527.0 169900.0 208080.0 214434.0 172617.0 166827.0 True False 135554.60232672718 216630.2418791116 150081.5235086145 183176.55231832236 200967.76167023418 162633.7730562443 218853.3642567404 224397.38646980422 153175.05572240608 195662.82466699585 0.6927969201989772 1.1071609655426409 0.7670415867911676 0.9361847485851018 1.0271126465247906 0.831194036644597 1.1185229725126027 1.1468575435916994 0.7828521129810891 1.0 17.57801014883144 -6.265174637993174 0.998522850873532 1.0046515694988127 0.8715723125257805 0.11469167646816492 0.1461758326360961 1.2806065188184463 2.6956444404730955 0.06603753380359167 0.10254392061521643 5.430319242152218e-07 6.265174637993174 -0.13307925697303224 TLHCEGTEINS(ph)DDEQESKEVEETATAK ddPTM_PC-9_AZD4547_30min_R2 5 TLHCEGTEINSDDEQESKEVEETATAK 27 1 Q9BPX3;H0Y9Z8 Q9BPX3 NCAPG Condensin complex subunit 3 1 TLHCEGT(0.039)EINS(0.96)DDEQES(0.001)KEVEETATAK;T(0.001)LHCEGT(0.231)EINS(0.769)DDEQESKEVEETATAK;TLHCEGTEINS(1)DDEQESKEVEETATAK;TLHCEGT(0.006)EINS(0.994)DDEQES(0.001)KEVEETATAK;TLHCEGT(0.02)EINS(0.973)DDEQES(0.007)KEVEETATAK 105.5 2.9346e-10 107191900.0 176631.3 147858.2 173134.3 229261.9 220484.5 217712.0 203168.0 206234.3 178231.7 222359.8 True False 232796.37924072632 195650.47162530804 170838.426058058 176409.11101604582 189874.03301450182 204098.43422343853 221249.5584114328 174365.5277277521 187652.66379477305 214575.05108305547 1.0849182049157147 0.9118043809742713 0.7961709676673064 0.822132443290265 0.8848840163668765 0.9511750466480757 1.0311057007545292 0.8126085807630101 0.874531604898178 1.0 17.711122816275953 -6.74373804954175 24.271852972266693 0.9282485705258654 0.890546534321357 0.026196273052053853 0.09184941187925384 774.9379334729673 1062582.181808442 0.032293326496830276 0.03221636081233729 1.804105582886519e-07 6.74373804954175 -0.037702036204508405 TLHCEGTEINS(ph)DDEQESKEVEETATAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TLHCEGTEINSDDEQESKEVEETATAK 27 1 Q9BPX3;H0Y9Z8 Q9BPX3 NCAPG Condensin complex subunit 3 1 TLHCEGTEINS(0.986)DDEQES(0.013)KEVEETATAK;TLHCEGT(0.002)EINS(0.994)DDEQES(0.004)KEVEETATAK;TLHCEGTEINS(1)DDEQESKEVEETATAK 101.2 6.1134e-10 22494700.0 67006.0 54649.0 55386.0 79495.0 75240.0 65866.0 77168.0 86824.0 63136.0 59294.0 True False 78348.79237117474 60074.191557341124 56706.61229257468 75041.15287626717 60497.262114859324 62411.87100953383 69858.08839206125 84544.9619976324 64059.244558422884 70043.53282895425 1.118572824738893 0.8576693540578803 0.8095909786711041 1.0713501995896904 0.8637094628363928 0.8910440191808018 0.9973524402695985 1.2070345195764258 0.9145633004385294 1.0 16.09596423125746 -7.520813507217126 24.984393864737353 1.0569180334629042 0.9302719486246618 0.1464983867504004 0.11278484517040602 130.14655548963893 1574523.3792515483 0.050423709706559454 0.029709226727094116 3.014300133515334e-08 7.520813507217126 -0.12664608483824247 TLHCEGTEINS(ph)DDEQESKEVEETATAK ddPTM_PC-9_Lapatinib_30min_R1 6 TLHCEGTEINSDDEQESKEVEETATAK 27 1 Q9BPX3;H0Y9Z8 Q9BPX3 NCAPG Condensin complex subunit 3 1 TLHCEGTEINS(1)DDEQESKEVEETATAK;T(0.001)LHCEGT(0.278)EINS(0.721)DDEQESKEVEETATAK;TLHCEGT(0.051)EINS(0.949)DDEQESKEVEETATAK;TLHCEGTEINS(1)DDEQESKEVEETATAK;TLHCEGTEINS(1)DDEQESKEVEETATAK;TLHCEGT(0.227)EINS(0.772)DDEQESKEVEETATAK 123.55 4.6521e-13 276799000.0 342034.0 341988.0 388387.0 435571.0 435520.0 410725.0 347252.0 363303.0 414904.0 306880.0 True False 337156.5324386457 341196.1477976804 356455.32007717574 467604.3443622606 409903.5698652641 393159.24919673864 365231.00944291515 380183.38368280686 368173.14238718734 359923.79910810373 0.9367442032844852 0.9479677327344546 0.9903632962323611 1.2991759520237083 1.1388620893672798 1.0923402402702818 1.0147453720703181 1.0562885383653613 1.0229196938338772 1.0 18.457331974643488 -5.53899216780639 24.999994940172293 1.094798895654227 0.94905826099151 0.3605874347902289 0.08118834953045535 248.4254817920316 385430.9098683447 0.023525038870608986 0.04076089095483717 2.8907320142013626e-06 5.53899216780639 -0.14574063466271692 TLHPDLGTDK ddPTM_PC-9_Lapatinib_30min_R1 2 TLHPDLGTDK 10 0 P00338-3;P00338;P00338-4;P00338-2;P00338-5 P00338-3 LDHA L-lactate dehydrogenase A chain 0 ; 131.09 0.00016068 13373300.0 197301.0 206538.0 204750.0 183846.0 177282.0 168747.0 223670.0 200750.0 168896.0 208332.0 False True 194487.45155942783 206059.77395065688 187916.24535785662 197366.64813227757 166854.62130982216 161530.0841784697 235250.53817428456 210077.5778739061 149873.15392627328 244341.9086150598 0.795964362649825 0.8433255478710645 0.7690708745911571 0.8077478368363414 0.6828735285549711 0.661082190501126 0.9627924227476755 0.8597689158795339 0.6133747369649383 1.0 17.89854180495057 -9.833387630712243 7.156801413788698 0.9999999974931465 0.781607722951174 0.31568997868952053 0.09816818801287905 65941242.74380784 0.0 0.0969414725738519 0.024235368143462985 1.4676157684654987e-10 9.833387630712243 -0.21839227454197252 TLHS(ph)PPLQLQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLHSPPLQLQQR 12 0 A0A2R8YGT1;F8W9A8;B7WPL9;Q6PFW1-7;Q6PFW1-4;Q6PFW1-3;Q6PFW1-2;Q6PFW1 A0A2R8YGT1 PPIP5K1 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 1 T(0.137)LHS(0.863)PPLQLQQR;T(0.071)LHS(0.929)PPLQLQQR 69.258 0.018459 21636000.0 49829.0 50392.0 44040.0 70355.0 69793.0 66620.0 58942.0 65566.0 54690.0 58127.0 True False 58264.06553238923 55394.58473087404 45090.08062263007 66413.2374439875 56117.56266324263 63126.32992219262 53358.58705687432 63844.96197291933 55489.73778668509 68664.96496692128 0.8485268369459943 0.8067372459530108 0.6566679331206504 0.9672070389314473 0.8172663117250079 0.9193382673770117 0.7770860595731656 0.9298040420420524 0.8081230044086786 1.0 16.067286557761946 -14.522878711085488 0.12478428779087337 1.5297582117642923 0.7649250740689051 0.26667785479045825 0.08333936199689429 199.60851403609382 1.5883569578671004 26.610657483343015 0.6962132614099836 3.0000002362096636e-15 14.522878711085488 -0.7648331376953872 TLHS(ph)PPLQLQQR ddPTM_PC-9_Lapatinib_30min_R1 3 TLHSPPLQLQQR 12 0 A0A2R8YGT1;F8W9A8;B7WPL9;Q6PFW1-7;Q6PFW1-4;Q6PFW1-3;Q6PFW1-2;Q6PFW1 A0A2R8YGT1 PPIP5K1 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 1 T(0.285)LHS(0.715)PPLQLQQR;T(0.11)LHS(0.89)PPLQLQQR;T(0.008)LHS(0.992)PPLQLQQR 88.706 0.004471 28182100.0 105015.0 94217.3 90943.0 86446.3 88823.4 99834.0 94209.7 84661.4 98919.3 82151.0 True False 103517.46684260783 93999.14563054378 83466.01759013212 92803.84927840334 83598.98224552326 95564.33254442067 99087.41729439762 88595.07771563587 87777.96676759189 96350.69089067323 1.0743821957651198 0.9755938931169919 0.8662731612878518 0.9631882077909083 0.867653168573342 0.9918385811353982 1.0284038067441539 0.9195064082743583 0.9110258157587204 1.0 16.556007391072775 -4.816317919239406 3.8860824223858828 0.9422183619017099 1.0823190633930553 0.36542121836665786 0.051613458113540796 0.24416619455253427 6.470633650856377 0.013196808953500108 0.08981056033692618 1.526448233929912e-05 4.816317919239406 0.14010070149134535 TLHSCSVR ddPTM_PC-9_Lapatinib_30min_R1 1 TLHSCSVR 8 0 E9PP73;P53618 E9PP73 COPB1 Coatomer subunit beta 0 76.47800000000001 0.020899 877740.0 4286.3 5125.3 5730.0 7888.5 5898.0 6149.9 7385.6 5223.3 6311.7 4048.9 False True 4225.1765759888485 5113.432682747492 5258.9015184396385 8468.646605264576 5551.0912359141485 5886.883113117101 7767.9902299816595 5465.993586594138 5600.80988085247 4748.746970179875 0.8897455692040812 1.076796197998691 1.1074292969204969 1.7833434079440533 1.1689591529665946 1.2396708331869946 1.6357978807380888 1.1510391311472836 1.1794289980121473 1.0 12.21333117107692 -5.537278890031356 24.96404324875215 1.3292676165922794 1.010481153647283 0.25312221132470814 0.22704205528404828 283.3408485989905 491196.92702160444 0.060563987494297075 0.1049547163189842 2.9021583826128427e-06 5.537278890031356 -0.31878646294499635 TLHSDDEGTVLDDSR ddPTM_PC-9_AZD4547_30min_R2 2 TLHSDDEGTVLDDSR 15 0 O00170;E9PMH2 O00170 AIP AH receptor-interacting protein 0 ; 199.38 4.8324e-10 8789300.0 33519.0 29583.0 51496.0 57894.0 43733.0 45351.0 40329.0 45681.0 32127.0 37951.0 False True 44177.344761488566 39145.126222904684 50813.1293931113 44547.4327533836 37661.42783652918 42515.194800778896 43918.202872374866 38622.051094951035 33825.16763142956 36622.347041385394 1.2062947443419063 1.0688863326719176 1.387489702276304 1.216400267930463 1.0283728619023125 1.160908522676994 1.1992186853219629 1.0546033833196398 0.9236209681811257 1.0 15.160436632630702 -7.948289026178504 3.4732844811731107 0.9650890823604714 1.1792755193376174 0.48495818109361777 0.09198413617927223 0.21294395764447815 5.177098621968325 0.06338342062689305 0.025779966357050408 1.1264475475234042e-08 7.948289026178504 0.214186436977146 TLHSDDEGTVLDDSR ddPTM_PC-9_Lapatinib_30min_R1 2 TLHSDDEGTVLDDSR 15 0 O00170;E9PMH2 O00170 AIP AH receptor-interacting protein 0 ; 183.41 4.5418e-07 8641200.0 39961.0 45709.0 45889.0 38406.0 46316.0 33609.0 41772.0 40846.0 36923.0 28544.0 False True 39391.14881205011 45603.16361885261 42116.18355666257 41230.50535866024 43591.783940759546 32171.62141640556 43934.74976803428 42743.85427565409 32764.34292357302 33477.79236751077 1.1766351968380713 1.3621914825873993 1.258033477665484 1.2315777846412972 1.3021104695978734 0.9609839580589308 1.3123550467644243 1.2767823459331737 0.9786888742212844 1.0 15.030916774658298 -8.425723997782983 0.3421075645059385 0.9673860582819228 1.2846083568863724 0.32663849903495923 0.11728699862530284 1.9724490727557982 0.6859541892012342 0.22637185671819934 0.1366692389258733 3.7521138029817886e-09 8.425723997782983 0.3172222986044496 TLIPS(ph)PPPRPK ddPTM_PC-9_AZD4547_30min_R2 2 TLIPSPPPRPK 11 1 J3KSG3;J3KSS7;Q9NZ52-3;Q9NZ52-4;Q9NZ52-2;Q9NZ52 J3KSG3 GGA3 ADP-ribosylation factor-binding protein GGA3 1 T(0.097)LIPS(0.903)PPPRPK;T(0.003)LIPS(0.997)PPPRPK 56.568999999999996 0.037757 99030000.0 203395.0 188130.0 209400.0 312690.0 299660.0 244098.0 208390.0 215229.0 201408.0 194110.0 True False 268070.37912118447 248939.34341733606 206623.21918047074 240604.1515123418 258057.38150811306 228834.51347226108 226936.30629507828 181970.30352039632 212054.01569741868 187314.267982486 1.4311263205334108 1.3289929597921075 1.1030831842440862 1.2844945241162218 1.3776707150372633 1.2216608800652455 1.211527070197861 0.9714705958085941 1.1320761519205034 1.0 17.515101270246213 -7.539990390793171 2.5657900278194674 1.0382849768825215 1.288510201748582 0.5988822751683411 0.09291173093093517 0.21311219562631253 2.8178203888491775 0.052411173999946145 0.028173764213540543 2.8840953159609034e-08 7.539990390793171 0.2502252248660606 TLLEEEYFR ddPTM_PC-9_Lapatinib_30min_R1 1 TLLEEEYFR 9 0 P52701-2;P52701;P52701-3;A0A087WWJ1;A0A494C0M1;P52701-4 P52701-2 MSH6 DNA mismatch repair protein Msh6 0 94.309 0.026670999999999997 1682300.0 15519.0 14062.0 15123.0 12034.0 11921.0 14333.0 13403.0 14996.0 14357.0 12434.0 False True 15297.696214163943 14029.440302966705 13879.645316468177 12919.02050424718 11219.830217587752 13720.011001854886 14096.941758617328 15692.768905589512 12739.963474087628 14583.20033273643 1.0489944501292772 0.9620275373625197 0.9517557874666983 0.8858837710160581 0.7693668030056084 0.9408093346325461 0.96665625082119 1.0760853960404233 0.8736054626835856 1.0 13.832019738275438 -9.415964287830928 11.58049998238623 1.0 0.9405335076415688 0.04280158094263442 0.08256663663679474 0.0 0.0 0.08496597378138557 0.02060727555788903 3.837387991546287e-10 9.415964287830928 -0.059466492358431156 TLLISS(ph)LSPALPAEHLEDR ddPTM_PC-9_AZD4547_30min_R2 2 TLLISSLSPALPAEHLEDR 19 0 Q8NDT2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 T(0.001)LLIS(0.151)S(0.561)LS(0.287)PALPAEHLEDR;TLLIS(0.133)S(0.56)LS(0.306)PALPAEHLEDR 95.344 0.00040548 1663800.0 9813.2 10072.5 15970.6 23273.0 18756.5 17777.7 12604.0 16546.5 12228.1 15227.3 True False 12933.593472759907 13328.23864652697 15758.819408995338 17907.769414265676 16152.48373575697 16666.05760864826 13725.731582816647 13989.618625743897 12874.45240183908 14694.1968618294 0.8801837619555138 0.9070409748728268 1.0724519044611054 1.2186967129033137 1.0992423667410984 1.1341931624681778 0.9340919896392227 0.9520505786937046 0.8761589709800741 1.0 13.842958887560792 -7.289343735611995 23.251788271592055 0.936579530238618 1.0560390239204822 0.23624951475995304 0.09784954945414369 507.99176477746045 423289.26316908264 0.04618116605936628 0.031147667003105586 5.13636957024685e-08 7.289343735611995 0.11945949368186426 TLLISS(ph)LSPALPAEHLEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLLISSLSPALPAEHLEDR 19 0 Q8NDT2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 T(0.004)LLIS(0.089)S(0.461)LS(0.445)PALPAEHLEDR 73.98100000000001 0.0025529 1928500.0 4733.3 6523.6 5400.4 7051.8 10776.0 5183.6 6595.7 5573.9 5268.6 5458.8 True False 5534.554203063635 7171.219895029567 5529.16601713105 6656.710508244065 8664.520156163251 4911.762890793727 5970.907547267243 5427.59103103522 5345.643307788056 6448.437228162973 0.8582783715241833 1.1120864856542148 0.8574427914073368 1.0322982565716041 1.3436620144678983 0.761698178489207 0.9259464481083631 0.8416909150221238 0.8289827625895831 1.0 12.654733851964245 TLLISSLS(ph)PALPAEHLEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLLISSLSPALPAEHLEDR 19 0 Q8NDT2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 TLLIS(0.012)S(0.051)LS(0.937)PALPAEHLEDR 106.02 0.00012999 1451600.0 5388.5 6704.6 6512.5 7440.2 8257.1 6977.5 7417.2 5786.0 6426.3 4237.4 True False 6300.666622273764 7370.188378842234 6667.782698793786 7023.3497154538545 6639.180529088307 6611.587616813264 6714.5891201222885 5634.123630773752 6520.272480134837 5005.607076760059 1.2587217745328803 1.4723865189220324 1.3320627441476272 1.403096489147487 1.3263487180031714 1.3208363172390063 1.341413542284743 1.125562503084143 1.3025937474011973 1.0 12.28932933344747 -8.794721046292564 0.40290855558427413 0.9743220571159713 1.3855644103259435 0.662102232330937 0.07466534715055756 0.9931194471487794 0.3627989861583347 0.13032287669655668 0.05363787368442631 1.6042755094842064e-09 8.794721046292564 0.41124235320997216 TLLISSLS(ph)PALPAEHLEDR ddPTM_PC-9_Lapatinib_30min_R1 1 TLLISSLSPALPAEHLEDR 19 0 Q8NDT2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 TLLIS(0.02)S(0.066)LS(0.914)PALPAEHLEDR 83.064 0.00093829 1326800.0 4672.3 5683.2 6696.9 3753.6 5719.6 5059.4 3809.7 4527.3 3995.9 4327.8 True False 4605.672145205121 5670.040899574767 6146.306732781576 4029.6522656425295 5383.184373166254 4843.021256037443 4006.9476249947384 4737.654885721215 3545.8396633075663 5075.854463568985 0.9073688338114279 1.1170613618397545 1.210891048373346 0.7938864864161532 1.0605474234541343 0.9541292585903202 0.789413418716764 0.9333709072482012 0.6985700021064789 1.0 12.309434989046514 -6.7362009929570705 1.0013236196081596 0.8464500143848336 1.0479810311743352 0.23180774009534155 0.13177949427490365 0.722698537483798 1.558334144023382 0.07352094604623369 0.06871715334044194 1.835688583834111e-07 6.7362009929570705 0.20153101678950158 TLLS(ph)ESSSQSSKSPSLSSK ddPTM_PC-9_AZD4547_30min_R2 1 TLLSESSSQSSKSPSLSSK 19 1 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 T(0.016)LLS(0.554)ES(0.175)S(0.175)S(0.045)QS(0.001)S(0.001)KS(0.011)PS(0.019)LS(0.002)SK 58.457 0.011399 111240000.0 28428.0 29406.0 39200.0 63923.0 53661.0 49044.0 49535.0 48696.0 49010.0 53951.0 True False 37467.51266086685 38910.91443432832 38680.182387175 49186.539950505095 46211.09640628338 45977.27092697845 53943.5190379897 41171.15212275861 51600.56854410193 52062.19191140634 0.7196683674906524 0.7473929353674273 0.7429610811046266 0.9447650616440677 0.8876133468394933 0.8831220745606997 1.0361361490462175 0.7908071214677075 0.9911332321910312 1.0 15.667948432612002 -5.756726295965782 24.806347948933496 0.924933742986396 0.7377459417023119 0.6454442146609574 0.06659926008022926 65.26450526072202 343500.3880707284 0.01721782838744207 0.028603542529032685 1.7509498365348011e-06 5.756726295965782 -0.18718780128408408 TLLSDPTYR ddPTM_PC-9_Lapatinib_30min_R1 2 TLLSDPTYR 9 0 P31948-2;P31948;P31948-3;F5H783 P31948-2 STIP1 Stress-induced-phosphoprotein 1 0 ; 139.97 0.0036915999999999997 6450400.0 85751.0 81325.0 88690.0 81956.0 84194.0 83171.0 85093.0 70057.0 80396.0 67006.0 False True 84528.17501519252 81136.69695909292 81398.25055330058 87983.31763720134 79241.87445177276 79613.97021107055 89498.6991767534 73312.10397565228 71340.9558725883 78587.8978201173 1.075587684107191 1.0324324636448434 1.0357606299587754 1.1195530110576257 1.0083215946703699 1.0130563664306413 1.138835643391432 0.9328676044174006 0.9077855223444607 1.0 16.262019540644104 -7.7877250202925445 24.993745286637747 0.9402447976681555 1.05691409136524 0.5615544828849535 0.045818940034370086 161.19407691564132 153269.37505697075 0.024338715740448612 0.011697723281359108 1.630327971177269e-08 7.7877250202925445 0.11666929369708445 TLLSESSSQSSKS(ph)PSLSSK ddPTM_PC-9_Lapatinib_30min_R1 1 TLLSESSSQSSKSPSLSSK 19 1 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 T(0.001)LLS(0.012)ES(0.011)S(0.011)S(0.002)QS(0.016)S(0.012)KS(0.618)PS(0.251)LS(0.052)S(0.014)K 64.249 0.0053917 86288000.0 61961.0 54533.0 61674.0 45795.0 36558.0 37103.0 33693.0 37940.0 46497.0 24538.0 True False 61077.42477774424 54406.732188997536 56603.40178852466 49162.91706764166 34407.73031579338 35516.1911813174 35437.45867888484 39702.83090677953 41260.01822488351 28779.360605170245 2.1222648277589466 1.8904774478979671 1.966805397975235 1.7082699557546628 1.1955696579864943 1.2340854846836617 1.2313497566905103 1.3795591726817888 1.4336669528881438 1.0 14.812746919438741 -6.055414565815698 2.7392478679436123 1.2623413420986997 1.9836299684524366 0.8828299577550479 0.12355178861957733 0.0895522148342711 1.3308509084199491 0.038493885102387444 0.05543076034642008 8.802082487653361e-07 6.055414565815698 0.7212886263537368 TLLSESSSQSSKSPS(ph)LSSK ddPTM_PC-9_AZD4547_30min_R2 1 TLLSESSSQSSKSPSLSSK 19 1 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 TLLS(0.006)ES(0.022)S(0.022)S(0.002)QS(0.004)S(0.017)KS(0.381)PS(0.523)LS(0.021)S(0.002)K 64.52 0.0053008000000000005 111740000.0 36754.0 39433.0 55259.0 93516.0 85236.0 74662.0 66743.0 71051.0 59529.0 65017.0 True False 48441.00746930843 52178.94609565632 54526.22955441083 71957.33100779745 73402.45268045661 69993.37333720885 72682.99770167655 60071.70053955395 62675.58140913783 62740.77461963459 0.7720817564491612 0.8316592584645429 0.8690716664716945 1.1468989894377006 1.169932203187773 1.1155962571635922 1.158465099328413 0.9574587005617659 0.9989609116098422 1.0 15.937115720860493 -5.653141342643064 4.839513222838862 1.0846983480112888 0.8133855634041098 0.7287896824573775 0.07142983533426811 0.11421173572041748 4.348675408212881 0.021647500281568248 0.03828344755595238 2.22258642448201e-06 5.653141342643064 -0.271312784607179 TLLSESSSQSSKSPS(ph)LSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLLSESSSQSSKSPSLSSK 19 1 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 T(0.013)LLS(0.196)ES(0.062)S(0.062)S(0.021)QS(0.021)S(0.021)KS(0.145)PS(0.345)LS(0.09)S(0.024)K;TLLS(0.001)ES(0.008)S(0.008)S(0.007)QS(0.007)S(0.007)KS(0.387)PS(0.566)LS(0.009)S(0.001)K 65.105 0.005104600000000001 210750000.0 40752.0 39087.0 46530.0 76966.0 73337.0 69054.0 67361.0 66557.0 57804.0 50844.0 True False 47650.50871131119 42967.29904301623 47639.45166600768 72653.84454713864 58967.14130405947 65432.68667738053 60980.07842859267 64809.94927297075 58649.27414557584 60061.61471911744 0.7933604338503435 0.7153870112209931 0.7931763388113536 1.20965519969634 0.9817774893303093 1.089426033305653 1.0152920249275763 1.079057723906679 0.9764851381344555 1.0 15.874155640923844 -5.649367902655334 7.140525184984009 1.0503278501451496 0.7552096978383182 0.7894560400504071 0.06709327591858613 0.08579604811615897 5.0405951117057315 0.01695056019808197 0.029481619630858425 2.241981875344159e-06 5.649367902655334 -0.29511815230683147 TLLSESSSQSSKSPS(ph)LSSK ddPTM_PC-9_Lapatinib_30min_R1 1 TLLSESSSQSSKSPSLSSK 19 1 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 TLLSESSSQSSKS(0.005)PS(0.989)LS(0.005)SK 89.87700000000001 0.00048625 97939000.0 105290.0 88719.0 91601.0 82881.0 62753.0 72202.0 60923.0 66742.0 65033.0 37283.0 True False 103788.54529217868 88513.57660637918 84069.91937008552 88976.34522291106 59061.99191714486 69114.08877108256 64077.294841471594 69843.07697365004 57708.298712150245 43727.316873525226 2.37354021954678 2.0242169640179744 1.9225949676547796 2.0348000194080496 1.3506886802127125 1.580570080963001 1.4653836416902886 1.5972413120077953 1.3197310706042846 1.0 15.416247206312548 -1.5228787453213337 0.16325706903729553 0.9674550882205177 6.342975576971185 0.8561898337644944 0.14910422122674347 23.004811811128434 0.24181699026126408 0.43489040096190923 29.879155015227962 0.029999999997168087 1.5228787453213337 5.3755204887506665 up TLLTGDGGGEAT(ph)GSPLAQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLLTGDGGGEATGSPLAQGK 20 0 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;H0Y2S9;Q6WCQ1;H0Y7E2 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 TLLTGDGGGEAT(0.67)GS(0.33)PLAQGK;TLLTGDGGGEAT(0.71)GS(0.29)PLAQGK 119.68 3.1228e-05 15566000.0 49525.0 44879.0 94856.0 57290.0 87488.0 74675.0 72509.0 55891.0 75693.0 51478.0 True False 57908.60433666292 49334.29052502177 97117.72678338342 54080.227036686 70345.35443786306 70758.91154217566 65640.42260030011 54423.920471409525 76799.86692791269 60810.553900376246 0.9522788500090381 0.8112784271928253 1.5970538098121572 0.8893230462147032 1.1567951601478148 1.1635959057057341 1.0794248430599147 0.8949749176856748 1.2629364806268852 1.0 15.892034110099699 -10.30416524875904 14.948596486739614 0.9999995797821402 1.0886891303287558 0.015104184473826776 0.21724837495645943 0.0 0.0 0.2022865702869092 0.04906169976099163 4.964034043488329e-11 10.30416524875904 0.08868955054661565 TLLTGDGGGEAT(ph)GSPLAQGK ddPTM_PC-9_Lapatinib_30min_R1 1 TLLTGDGGGEATGSPLAQGK 20 0 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;H0Y2S9;Q6WCQ1;H0Y7E2 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 TLLTGDGGGEAT(0.71)GS(0.29)PLAQGK 111.58 0.00013033 5860700.0 30953.0 41584.0 39430.0 35532.0 41939.0 46343.0 40940.0 43547.0 50819.0 36872.0 True False 30511.604543915004 41487.71480291333 36188.21760420158 38145.14181127727 39472.23047524641 44361.01792080942 43059.672879041515 45570.35259613938 45095.22907220583 43245.27607114828 0.7055476878842559 0.9593583062033559 0.836813194224122 0.8820649392668894 0.9127524220288397 1.0258003174225434 0.9957081279397684 1.0537648671999649 1.042778152185084 1.0 15.400254927074641 -6.490460791748075 0.9913830383987018 1.0373277967027288 0.8333520282819704 0.6649036607800235 0.06005773733334649 0.3238787259398465 0.686009395664031 0.02924386808538589 0.035478291894809263 3.232505021863961e-07 6.490460791748075 -0.20397576842075837 TLLTGDGGGEATGS(ph)PLAQGK ddPTM_PC-9_AZD4547_30min_R2 3 TLLTGDGGGEATGSPLAQGK 20 0 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;H0Y2S9;Q6WCQ1;H0Y7E2 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 T(0.017)LLT(0.053)GDGGGEAT(0.195)GS(0.735)PLAQGK;TLLTGDGGGEAT(0.01)GS(0.99)PLAQGK;TLLTGDGGGEAT(0.429)GS(0.571)PLAQGK 102.5 0.00022368 36046800.0 109056.0 108649.0 171797.0 224804.0 194059.0 154024.0 136940.0 213279.0 136036.0 183319.0 True False 143733.539494284 143767.664503004 169518.8595298343 172978.9109871776 167117.25755216938 144392.8549314275 149127.39471206864 180321.63121385404 143226.58523700162 176901.0576079612 0.8125080846764562 0.8127009891688398 0.95826933892907 0.9778285857992118 0.9446933772579575 0.816235114045634 0.8429988872229182 1.0193360834137766 0.8096423343856588 1.0 17.43258314768395 -10.678384924248109 0.013414168847869154 1.9120879353962004 2.102470177595353e-06 0.14056353518160714 0.07722676469901674 7133.282301097739 17.223671759018725 1333.8062821352112 1126.4734661739387 2.0970803736548857e-11 10.678384924248109 -1.9120858329260229 TLLTGDGGGEATGS(ph)PLAQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLLTGDGGGEATGSPLAQGK 20 0 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;H0Y2S9;Q6WCQ1;H0Y7E2 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 TLLTGDGGGEATGS(1)PLAQGK;TLLTGDGGGEAT(0.011)GS(0.989)PLAQGK 219.96 5.767e-37 7936500.0 48086.2 46165.0 61123.0 60756.0 73992.0 63231.0 69102.0 51560.0 51294.0 47487.8 True False 56226.24391425826 50747.95610614382 62580.40413026837 57352.03829360961 59493.798756016266 59915.05504818623 62556.15830484419 50206.60463233572 52044.07771128588 56096.96222678206 1.0023046112007554 0.9046471340281508 1.1155756327281294 1.0223733339027108 1.0605529496499628 1.0680623810959469 1.1151434199226273 0.8949968525811878 0.9277521570756065 1.0 15.775635027406372 -7.773948602780161 24.99667554525951 0.9335308686174718 1.039891921623321 0.3521437530847108 0.062095539707430834 259.904699876367 519349.5199331899 0.034746793352477844 0.0168695600511827 1.6828732113936333e-08 7.773948602780161 0.10636105300584908 TLLTGDGGGEATGS(ph)PLAQGK ddPTM_PC-9_Lapatinib_30min_R1 1 TLLTGDGGGEATGSPLAQGK 20 0 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;H0Y2S9;Q6WCQ1;H0Y7E2 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 TLLTGDGGGEAT(0.319)GS(0.681)PLAQGK 221.51 3.8544e-29 7604600.0 39063.0 32908.0 35873.0 37309.0 39692.0 35069.0 35414.0 38603.0 43014.0 32752.0 True False 38505.954456723135 32831.80354786148 32923.66041378448 40052.82831917549 37357.39459747445 33569.18061983179 37247.563637967185 40396.63630718004 38169.31036249952 38413.13956070322 1.0024162278085404 0.8547024253505312 0.857093712992559 1.0426856220872318 0.9725160459336992 0.8738983848686294 0.9696568430473093 1.0516358925399043 0.9936524532753075 1.0 15.229312261761404 -7.5323714566205044 10.282801103631469 1.0158036570456697 0.932516140817914 0.26991611669117355 0.059856009032164335 0.309633459037249 299.48780685935856 0.028837632061562528 0.01702317821014886 2.9351381236576006e-08 7.5323714566205044 -0.08328751622775565 TLMLPLTEGS(ph)LR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLMLPLTEGSLR 12 0 Q7L4E1-3;Q7L4E1 Q7L4E1-3 FAM73B Protein FAM73B 1 TLMLPLT(0.011)EGS(0.989)LR;TLMLPLT(0.03)EGS(0.97)LR 67.01899999999999 0.033356 7889000.0 106681.0 100345.0 92613.0 108530.0 142669.0 116294.0 114663.0 95061.0 103838.0 99593.0 True False 124739.98625420543 110306.58844299796 94821.24515675829 102449.4159590076 114714.03360798559 110195.33791611348 103801.290551769 92565.74947545512 105356.43430780403 117648.4225222458 1.060277593017609 0.9375951336886 0.8059712414658923 0.8708099417111669 0.975057983342655 0.9366495151711615 0.8823007425547207 0.7867997503999862 0.8955193112587845 1.0 16.844122450888605 -7.340602139837925 5.920281289825914 0.8725700176865028 0.9248523425488167 0.03493000636141941 0.07898281942629899 0.6583008736138595 38.711504659933325 0.034681908075228474 0.023206422583123852 4.564548859301079e-08 7.340602139837925 0.05228232486231388 TLMLPLTEGS(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 2 TLMLPLTEGSLR 12 0 Q7L4E1-3;Q7L4E1 Q7L4E1-3 FAM73B Protein FAM73B 1 TLMLPLTEGS(1)LR;TLMLPLTEGS(1)LR 118.76 0.00050178 5014000.0 102955.0 90089.0 55124.0 42985.0 45853.0 50394.0 38273.0 37710.0 71181.0 23736.7 True False 101486.84282036529 89880.40445555148 50591.917504793455 46146.260293756466 43156.016690466524 48238.76609415166 40254.58866877277 39462.14426712323 63163.84621084012 27839.55696783537 3.645418744903837 3.228514180717583 1.8172673352253839 1.6575788309803878 1.5501689463064061 1.7327418733669022 1.4459493272569384 1.4174846357187398 2.2688524204539933 1.0 14.764848632209059 -5.225306472648481 2.6385341437538554 1.5981044252467707 3.622413791100459 0.8594849418350513 0.29880483421146975 0.09296287887310936 1.2389657255633402 0.07664857881928328 0.2623636816985116 5.952419453337041e-06 5.225306472648481 2.0243093658536884 TLMPY(ph)AS(ph)LFQSHS(ph)CK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLMPYASLFQSHSCK 15 0 A0A3B3IRU1;Q9BWV7 A0A3B3IRU1 TTLL2 Probable tubulin polyglutamylase TTLL2 3 T(0.168)LMPY(0.881)AS(0.911)LFQS(0.251)HS(0.789)CK 44.382 0.036945 2778400.0 11394.0 14163.0 16551.0 15609.0 18553.0 16312.0 16625.0 17309.0 14396.0 13338.0 True False 13322.779158242045 15569.009039993827 16945.638610017035 14734.478335060781 14917.672833824874 15456.570004365154 15050.159645423208 16854.65709040146 14606.514265443737 15756.073816450093 0.8455646573788216 0.9881274498561335 1.0754988081056702 0.9351617989804848 0.9467887119347024 0.9809912154782975 0.955197330296214 1.0697244305116413 0.9270402281432472 1.0 13.943620460586944 -4.761277211357244 24.910587517825686 0.9874672657840904 0.8455645054189244 0.4288458503972339 0.048783829818017835 3.5362980552468852 541506.9740718453 0.011936497177722686 0.06709148758127684 1.7326976590409082e-05 4.761277211357244 -0.14190276036516603 TLNAETPKS(ph)SPLPAK ddPTM_PC-9_AZD4547_30min_R2 1 TLNAETPKSSPLPAK 15 1 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 T(0.001)LNAET(0.005)PKS(0.497)S(0.497)PLPAK 56.036 0.032122000000000005 5905000.0 13290.0 11992.0 17006.0 31635.0 24235.0 14412.0 19697.0 20902.0 16843.0 22890.0 True False 17515.943550827385 15868.179483658616 16780.489328476993 24342.039505877823 20870.388576550544 13510.815361708133 21449.994841854917 17672.07618017702 17733.286594334 22088.628067173748 0.7929846750807534 0.7183868294310485 0.7596890706587042 1.1020168129886212 0.944847661569636 0.6116638534824517 0.9710876916675548 0.8000531371361975 0.8028242650655028 1.0 14.431016194704814 -12.21542370647486 2.0671641901613 5.435612594051867 0.8358354991155098 0.12425651636428492 0.1323181826348772 5741060.208688698 222185.50060463077 120285032.88516349 0.03547434144209379 6.089425107176623e-13 12.21542370647486 -4.599777094936357 TLNAETPKS(ph)SPLPAK ddPTM_PC-9_Lapatinib_30min_R1 2 TLNAETPKSSPLPAK 15 1 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 T(0.001)LNAET(0.153)PKS(0.733)S(0.113)PLPAK;TLNAETPKS(0.654)S(0.346)PLPAK 92.671 0.0016599 194236000.0 163628.0 107086.0 142278.0 105958.0 107950.0 123598.0 104267.0 103419.0 130130.0 89250.0 True False 161294.63471429996 106838.04894634413 130580.45204896262 113750.50478552628 101600.59323786576 118312.00166101025 109665.43507765092 108224.22428962131 115473.38907035065 104676.74358185027 1.5408831913860432 1.0206474264534593 1.2474638356213037 1.0866836404457016 0.970612857844788 1.1302606253556036 1.047658069262537 1.0338898649918082 1.1031427337062518 1.0 16.67558142342918 TLNAETPKSS(ph)PLPAK ddPTM_PC-9_AZD4547_30min_R2 2 TLNAETPKSSPLPAK 15 1 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 TLNAETPKS(0.122)S(0.878)PLPAK;T(0.001)LNAET(0.063)PKS(0.267)S(0.669)PLPAK 135.61 0.00011505 273849000.0 167200.0 115537.0 251276.0 318720.0 247427.0 181176.0 199326.0 206519.0 185664.0 234033.0 True False 220366.12202395362 152882.07580082264 247943.9160591785 245244.0281749132 213076.03195090411 169847.03607915883 217065.62785437255 174606.23388450735 195477.81999943143 225839.5759041016 0.9757639737931841 0.6769498888261332 1.0978762914630298 1.0859213988209548 0.943484024435924 0.7520694076722898 0.9611496434378058 0.7731427637760465 0.8655605166493817 1.0 17.784938799155228 -6.554463538155249 24.8716743335852 0.8603117695776304 0.9571104587243038 0.09873989237343395 0.1281673315858579 435.529180662868 342957.6401953715 0.043260171301409044 0.04326050011022383 2.7895648486105945e-07 6.554463538155249 0.09679868914667333 TLNAETPKSS(ph)PLPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLNAETPKSSPLPAK 15 1 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 TLNAET(0.003)PKS(0.383)S(0.614)PLPAK;T(0.002)LNAET(0.026)PKS(0.202)S(0.77)PLPAK 66.939 0.014555000000000002 195554000.0 116817.0 77448.0 77956.0 132391.0 133074.0 144687.0 140747.0 154947.0 138363.0 112896.0 True False 136591.81085908005 85136.52560399908 79814.7666897765 124973.56148741332 106999.10497970178 137099.35901309366 127414.42523996254 150879.8054299172 140386.29711792123 133363.15111575546 1.0242095340153008 0.6383811786968273 0.5984769107659996 0.9370921460826895 0.8023138631962105 1.0280152940754623 0.9553945312027788 1.131345534112026 1.052661818076493 1.0 17.025000572396316 -6.689006559807474 1.2613877762370043 1.0561682326946664 0.7614238049721037 0.45341553914235144 0.12572050022665066 0.3815609426014606 1.2778980375632365 0.059788336425525855 0.05765977256038593 2.046413726404604e-07 6.689006559807474 -0.2947444277225627 TLNAETPKSS(ph)PLPAK ddPTM_PC-9_Lapatinib_30min_R1 2 TLNAETPKSSPLPAK 15 1 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 TLNAET(0.003)PKS(0.072)S(0.924)PLPAK;TLNAET(0.004)PKS(0.419)S(0.577)PLPAK 78.225 0.0057163000000000005 199990000.0 266757.0 157117.0 164925.0 149271.0 154514.0 175517.0 128758.0 137575.0 187258.0 153698.0 True False 262952.9962627574 156753.20523973962 151365.50312891084 160248.88729345828 145425.79030621191 168010.5470601107 135424.45922226744 143967.23674222955 166167.03212584124 180264.49451028794 1.4587065355110753 0.8695733769735421 0.8396856160727325 0.8889653380095471 0.8067356286731898 0.9320224013970877 0.7512542033868937 0.7986444426193597 0.9217956790506955 1.0 17.459755741211588 -4.761460555267339 7.026881628312897 0.8567992714055028 1.4713832998271907 0.8654509056393862 0.06981779811769134 0.03387538796527029 9.787729640171946 0.016362734486141055 0.09932494271770902 1.7319663291946827e-05 4.761460555267339 0.6145840284216879 TLNDELEIIEGMK ddPTM_PC-9_Lapatinib_30min_R1 4 TLNDELEIIEGMK 13 0 P10809;E7ESH4;E7EXB4 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 ;;; 168.82 0.0012085000000000002 19377300.0 74264.0 83339.0 85022.0 80405.0 69464.0 57237.5 85677.0 83157.0 76820.0 69079.0 False True 73204.98174165019 83146.03366583309 78031.81935441079 86318.25192321691 65378.26409147855 54789.58555212931 90112.93583921947 87020.77779955343 68167.72264953764 81019.21310801824 0.9035508854430641 1.0262508172595959 0.9631273417871322 1.06540471836148 0.8069476557901578 0.6762542297106924 1.1122415582965128 1.0740758205530043 0.841377249105759 1.0 16.305976452593143 -10.253923876126604 12.430829866421671 0.9999999999780669 0.9450586167847286 0.017268896930129896 0.13030754584006576 0.0 0.0 0.1319082170301925 0.03199244186484601 5.572834219549427e-11 10.253923876126604 -0.0549413831933383 TLNEWSSQINPDLVR ddPTM_PC-9_Lapatinib_30min_R1 2 TLNEWSSQINPDLVR 15 0 P48507 P48507 GCLM Glutamate--cysteine ligase regulatory subunit 0 ; 135.91 0.00012321 3217900.0 30490.7 31219.3 32415.0 29104.4 31388.6 28687.3 26376.9 27750.2 31525.5 26745.2 False True 30055.89702669042 31147.013628958073 29749.96382551848 31244.83466543223 29542.384260361956 27460.411052362513 27742.566818837084 29039.57559908575 27974.766211767765 31368.072184261095 0.9581684475264293 0.9929527529137115 0.9484154349927025 0.9960712434572023 0.9417978920357376 0.8754255247519085 0.884420523386735 0.9257685785885285 0.8918229353541236 1.0 14.937009246452693 -6.525398295999847 7.795768405814434 0.9087808152522098 0.9729626741527938 0.3730266837444257 0.03515575432834778 0.11140968886932458 54.835657390813125 0.010727868067824053 0.01114977093692887 2.982645948481415e-07 6.525398295999847 0.06418185890058403 TLNMT(ph)TSPEEK ddPTM_PC-9_AZD4547_30min_R2 1 TLNMTTSPEEK 11 0 P49915-2;P49915 P49915-2 GMPS GMP synthase [glutamine-hydrolyzing] 1 TLNMT(0.7)T(0.207)S(0.093)PEEK 125.82 0.0010806 11350000.0 93388.0 82175.0 97234.0 110350.0 118360.0 106780.0 89024.0 107240.0 86194.0 97882.0 True False 123083.44140892905 108736.46173029071 95944.61362843307 84910.51239050478 101927.75704231569 100103.02971989964 96946.96353766044 90668.52213004413 90750.03887146145 94455.18097296217 1.3030883022092956 1.1511963728216936 1.015768670814333 0.8989502906654792 1.0791124001074386 1.059793954008242 1.0263805811288589 0.9599105226001104 0.9607735429297275 1.0 16.52734231177984 -4.973052935418716 2.217798012959932 1.0002937512334706 1.3237235214586756 0.7942516695976722 0.04930605099240631 0.19688152533653425 1.5241551650155714 0.014380154416984226 0.10828354842518974 1.0640133195389918e-05 4.973052935418716 0.3234297702252049 TLNMT(ph)TSPEEK ddPTM_PC-9_Lapatinib_30min_R1 1 TLNMTTSPEEK 11 0 P49915-2;P49915 P49915-2 GMPS GMP synthase [glutamine-hydrolyzing] 1 T(0.001)LNMT(0.453)T(0.136)S(0.41)PEEK 121.04 0.0019730999999999998 19652000.0 48392.0 46459.0 50495.0 48376.0 47406.0 45846.0 42320.0 38951.0 41233.0 37856.0 True False 47701.92120599409 46351.42703993242 46343.49601633674 51933.73241760528 44617.67228378199 43885.27345224582 44511.12252664966 40760.80565761647 36588.90533726095 44399.35916005073 1.0743831016578032 1.0439661273678498 1.0437874981320743 1.1696955406584735 1.0049170332153734 0.9884213259486081 1.0025172292734237 0.9180494139719898 0.8240863388447867 1.0 15.438251233077782 -7.177305509726581 1.1507070316693542 0.907951602250075 1.073870476249162 0.5604269553684489 0.05761582261380468 0.36072929594202735 0.9455538290345146 0.037679897791349816 0.023075364002137687 6.648053262917453e-08 7.177305509726581 0.165918873999087 TLNMTTS(ph)PEEK ddPTM_PC-9_AZD4547_30min_R2 3 TLNMTTSPEEK 11 0 P49915-2;P49915 P49915-2 GMPS GMP synthase [glutamine-hydrolyzing] 1 TLNMT(0.146)T(0.198)S(0.656)PEEK;T(0.002)LNMT(0.198)T(0.198)S(0.601)PEEK;T(0.001)LNMT(0.302)T(0.155)S(0.542)PEEK 104.94 0.0023078000000000005 115500900.0 251781.0 208647.0 256427.0 306442.0 267743.0 260483.0 257584.0 261483.0 229018.0 263619.0 True False 331842.12062986137 276088.0624355333 253026.6104335747 235796.53138170447 230571.50603059042 244194.95683207214 280508.476993672 221076.81063157742 241123.42393048672 254389.77904937827 1.3044632605520257 1.0852954213303645 0.9946414175093923 0.9269103981411739 0.9063709512709447 0.9599244031918152 1.1026719628512434 0.86904753586293 0.9478502824741379 1.0 17.956681181179363 -4.730213271296926 1.5968499174337811 0.9577585377380234 1.464013215481885 0.7593587464172281 0.059107301971727796 0.5759320471898776 1.2887156379085412 0.01707978810598519 0.47574589078696794 1.8611729361357482e-05 4.730213271296926 0.5062546777438616 TLNMTTS(ph)PEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TLNMTTSPEEK 11 0 P49915-2;P49915 P49915-2 GMPS GMP synthase [glutamine-hydrolyzing] 1 T(0.002)LNMT(0.207)T(0.207)S(0.583)PEEK;TLNMT(0.075)T(0.2)S(0.725)PEEK;TLNMT(0.181)T(0.181)S(0.638)PEEK;T(0.004)LNMT(0.195)T(0.195)S(0.606)PEEK 86.11399999999999 0.009769700000000001 163597000.0 355753.0 347230.0 265776.0 383752.0 384067.0 339703.0 406066.0 362953.0 301384.0 289913.0 True False 415974.95645796706 381700.6996368744 272113.1078010934 362251.61958077014 308811.82839802804 321888.3766670464 367600.48881674674 353425.86833049107 305791.17083748966 342471.93194995547 1.2146249594514285 1.1145459350889266 0.7945559399619838 1.0577556458953985 0.901714270830095 0.9398971029079344 1.0733740622880104 1.0319849171818736 0.8928941098804387 1.0 18.38562622806929 -5.021713165626087 13.567909688451588 0.9663382547840379 1.1896593636700699 0.5166246638144084 0.08102980921981924 1.562339997379862 979.7998747517759 0.020052520102421242 0.05614994973403956 9.512328380009159e-06 5.021713165626087 0.22332110888603196 TLNMTTS(ph)PEEK ddPTM_PC-9_Lapatinib_30min_R1 7 TLNMTTSPEEK 11 0 P49915-2;P49915 P49915-2 GMPS GMP synthase [glutamine-hydrolyzing] 1 TLNMT(0.06)T(0.209)S(0.73)PEEK;T(0.007)LNMT(0.189)T(0.189)S(0.615)PEEK;TLNMT(0.189)T(0.189)S(0.622)PEEK;TLNMT(0.18)T(0.18)S(0.639)PEEK;T(0.001)LNMT(0.198)T(0.198)S(0.603)PEEK;TLNMT(0.007)T(0.077)S(0.916)PEEK;TLNMT(0.006)T(0.264)S(0.73)PEEK 211.83 9.4904e-07 209457900.0 934788.0 781122.0 744700.0 733058.0 785077.0 728088.0 729342.0 674311.0 697658.0 602884.0 True False 921457.7517008753 779313.3600009936 683473.6406251296 786969.5307298031 738900.3143807686 696949.3734960251 767103.7600621867 705641.9507533312 619080.4093755676 707091.6961075645 1.3031658507282216 1.1021390355607323 0.9665983130441937 1.1129667270340668 1.0449851390538254 0.9856562838067943 1.0848716853627045 0.9979497067180764 0.8755305892906308 1.0 19.43153779122762 TLNPS(ph)PAGWFVQQHPELELMSSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLNPSPAGWFVQQHPELELMSSFR 24 0 Q8N1F8 Q8N1F8 STK11IP Serine/threonine-protein kinase 11-interacting protein 1 T(0.043)LNPS(0.957)PAGWFVQQHPELELMSSFR 62.713 0.0017125 2300200.0 2600.9 3545.9 4342.3 5494.1 6679.6 4411.7 4805.6 6028.1 5705.4 4464.5 True False 3041.180999883422 3897.9135179632945 4445.836900264454 5186.283389112527 5370.780329909805 4180.342685646014 4350.378778468919 5869.868762299904 5788.830681443647 5273.878509037446 0.5766498023555113 0.7390980871636947 0.8429919067430091 0.9833907588552119 1.0183739198213053 0.7926505471224787 0.8248917321500685 1.1130079603163316 1.0976420240860245 1.0 12.364648621805399 -4.287054414781985 0.6616196972159728 0.9853724777235559 7.39140408451277e-18 0.6472711134497404 0.09690895026819074 4.166271869478043 0.8651584622349421 0.04750421227927522 3.585439335024702 5.163516691090273e-05 4.287054414781985 -0.9853724777235559 TLNYQS(ph)LPHR ddPTM_PC-9_AZD4547_30min_R2 1 TLNYQSLPHR 10 0 Q70EL1-7;Q70EL1;Q70EL1-9;Q70EL1-10;Q70EL1-8 Q70EL1-7 USP54 Inactive ubiquitin carboxyl-terminal hydrolase 54 1 TLNYQS(1)LPHR 100.19 0.0044358 0.0 15516.0 11037.0 19950.0 24981.0 25604.0 21691.0 19470.0 16895.0 17613.0 18827.0 True False 20449.76524715107 14604.494409701483 19685.449964901563 19222.016402602618 22049.326557210647 20334.65834102213 21202.79228161219 14284.265958477214 18543.987222347838 18167.872460492807 1.125600440647103 0.8038637678385229 1.0835308321163541 1.0580224208641993 1.2136438432820524 1.1192647012048953 1.1670487189801122 0.7862376835559176 1.0207021907861207 1.0 14.149101862940464 -7.749071300521554 24.99890430233315 0.9276024066616216 1.0765865176424807 0.2407529215281463 0.11826052100409393 320.90044725790943 648620.8548532827 0.058166086382533136 0.03327497116557872 1.782086168510025e-08 7.749071300521554 0.14898411098085906 TLNYQS(ph)LPHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLNYQSLPHR 10 0 Q70EL1-7;Q70EL1;Q70EL1-9;Q70EL1-10;Q70EL1-8 Q70EL1-7 USP54 Inactive ubiquitin carboxyl-terminal hydrolase 54 1 TLNYQS(1)LPHR 87.49799999999999 0.0096672 0.0 11620.0 14290.0 17968.0 20220.0 18868.0 18474.0 14997.0 12732.0 15436.0 13884.0 True False 13587.036494538574 15708.616760680057 18396.425264019468 19087.138954124475 15170.950845071302 17505.19091838168 13576.375591122518 12397.798490669098 15661.722297957045 16401.059294316467 0.8284243261803798 0.9577806212872869 1.1216607984823557 1.1637747667151492 0.92499823168913 1.0673207507058908 0.8277743130791071 0.7559144972401486 0.9549213875096697 1.0 14.001501376667443 -7.26474661843166 24.97243385703766 0.8643120866810955 1.0163678602559518 0.22877895563823425 0.11055385603203846 386.81856366964 2920785.7354839006 0.04650295660900187 0.032821183875674786 5.4356737393525036e-08 7.26474661843166 0.15205577357485633 TLPGACGS(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 2 TLPGACGSPQK 11 0 Q9UBZ9-2;Q9UBZ9 Q9UBZ9-2 REV1 DNA repair protein REV1 1 T(0.002)LPGACGS(0.998)PQK;TLPGACGS(1)PQK 110.51 0.0019275 14766600.0 51184.0 49202.0 66981.0 64668.0 68810.0 60881.0 56602.0 63896.0 56001.0 64299.0 True False 67459.4473066628 65105.584302449264 66092.78817539205 49759.79171064033 59256.919247057616 57074.10144575025 61639.46834739672 54022.341384010695 58961.0985316926 62047.9115810924 1.0872154370336524 1.049279220580385 1.0651895686934325 0.8019575589680834 0.9550187546540202 0.9198392015363529 0.9934172928098979 0.8706552727952361 0.9502511370529282 1.0 15.921095032253092 -5.709836539190111 23.521943681286842 0.9255145511743028 1.0654343092569352 0.5724392128576359 0.05539386990384846 39.49124856907875 18000.45672027023 0.014299291043052675 0.02476703074005197 1.950578625123653e-06 5.709836539190111 0.13991975808263235 TLPGACGS(ph)PQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLPGACGSPQK 11 0 Q9UBZ9-2;Q9UBZ9 Q9UBZ9-2 REV1 DNA repair protein REV1 1 TLPGACGS(1)PQK;TLPGACGS(1)PQK 118.73 0.0010348 11229500.0 52876.0 52164.0 51103.0 57887.0 60868.0 46802.0 56837.0 50667.0 46538.0 45076.0 True False 61826.86245139599 57342.49718013402 52321.489329206735 54643.77906218615 48941.35234459404 44347.62072978775 51452.98789575454 49337.044936123995 47218.53020875387 53247.92197858034 1.1611131505989405 1.0768964318119452 0.9826015248116861 1.0262143015490315 0.9191222967213879 0.8328516697351522 0.966291002237649 0.9265534335024463 0.8867675667746834 1.0 15.700437604236388 -4.933886548692407 0.7905588694804688 0.91845536998637 1.2668688095184135 0.7118757569981071 0.048542211476176864 1.1646586962934617 0.6473972057910173 0.019499561121990108 0.34405815479083324 1.1644301752789411e-05 4.933886548692407 0.3484134395320435 TLPGACGS(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 2 TLPGACGSPQK 11 0 Q9UBZ9-2;Q9UBZ9 Q9UBZ9-2 REV1 DNA repair protein REV1 1 TLPGACGS(1)PQK;TLPGACGS(1)PQK 124.48 0.00050912 17959200.0 74425.0 77874.0 80770.0 87639.0 91547.0 87155.0 68403.0 75729.0 79683.0 69766.0 True False 73363.68585212641 77693.68753756424 74129.40238121635 94084.26441513354 86162.38544832703 83427.58381822819 71944.57264155055 79247.6458023064 70708.26144081102 81824.96014264831 0.8965929922144652 0.9495108509936102 0.9059509745190706 1.1498235287999303 1.0530085843991506 1.0195860000760888 0.879249712020966 0.9685021008766911 0.8641404935308595 1.0 16.320253374075612 -10.004096022821898 10.427078058489467 0.9999895110128377 0.9701390430581855 0.012083959497648733 0.08429280609282411 0.0 0.0 0.08680019630364642 0.021052139863781287 9.906128954549344e-11 10.004096022821898 -0.029850467954652182 TLPIRS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLPIRSPK 8 1 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 TLPIRS(1)PK 57.148999999999994 0.039032 15541000.0 33890.0 30305.0 29049.0 30154.0 31071.0 25847.0 36687.0 28781.0 26860.0 24240.0 True False 39626.90764198899 33313.48012123231 29741.638328945985 28464.569140587028 24982.860595039765 24491.53781895697 33211.74176912129 28025.52924599019 27252.776685872384 28634.52011626558 1.3838858650709247 1.1634027735044488 1.0386637599717103 0.9940648219356045 0.8724735212464231 0.8553151133496655 1.1598497769220746 0.9787322829995864 0.9517455356407978 1.0 14.805467805199111 -4.808635713576838 1.350940267189622 0.9714325133641393 1.546230554775899 0.7289291988537174 0.07814481615975306 0.6829268003975694 1.1508405645167699 0.024588093618052528 0.5357199763933849 1.5536896992107156e-05 4.808635713576838 0.5747980414117597 TLPQQES(ph)LEIELAEEKPVKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLPQQESLEIELAEEKPVKR 20 2 Q5VZK9-2;Q5VZK9;A0A0U1RQQ1 Q5VZK9-2 LRRC16A Leucine-rich repeat-containing protein 16A 1 TLPQQES(1)LEIELAEEKPVKR;T(0.033)LPQQES(0.967)LEIELAEEKPVKR 62.203 0.0033350000000000003 9002800.0 98063.0 84065.0 95444.0 123045.0 129334.0 115798.0 78948.0 103922.0 73612.0 76323.0 True False 114663.12906746438 92410.41763376987 97719.74693338564 116151.18756727235 103991.93113188761 109725.34902927146 71469.47390597714 101194.15761446075 74688.43623977811 90159.75572746422 1.2717772818070758 1.0249630435236423 1.0838510613180212 1.2882819682694715 1.153418510207985 1.2170102740844853 0.7926981759136056 1.1223872203064906 0.8284010491947986 1.0 16.460195986327847 -7.243797783846647 24.939126712606843 0.9460705363148375 1.1667464170985526 0.5147023370572137 0.11262584130814768 678.2826009734125 958858.5912208648 0.04153182840162028 0.032096969712080405 5.704298139282865e-08 7.243797783846647 0.22067588078371514 TLPS(ph)PIDAK ddPTM_PC-9_AZD4547_30min_R2 1 TLPSPIDAK 9 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 TLPS(1)PIDAK 110.54 0.0022949999999999997 4019500.0 35527.0 38297.0 56362.0 82613.0 80352.0 78694.0 72165.0 77582.0 61798.0 80616.0 True False 46823.84699249392 50675.75631134705 55614.60305372338 63567.849208126594 69196.51177647997 73773.25173981811 78587.54519787083 65593.48455700373 65064.516116882536 77793.65837760063 0.6018979948881804 0.6514124334579215 0.7148989289560994 0.817134076656689 0.8894878222670646 0.9483196095719272 1.0102050326058298 0.8431726431815458 0.8363730087235075 1.0 16.24736493321742 -5.749198396504519 1.286099621349882 0.9234342780319973 0.6100912313583364 0.835055837440807 0.05394811024327534 0.19904610226790992 0.6504336520414428 0.0199851085754402 0.051397897822753225 1.7815647185169094e-06 5.749198396504519 -0.31334304667366086 TLPS(ph)PIDAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLPSPIDAK 9 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 T(0.025)LPS(0.975)PIDAK 113.93 0.0010712 0.0 44288.0 28849.0 56866.0 72913.0 85573.0 72668.0 71820.0 87852.0 62462.0 65407.0 True False 51785.08367212778 31712.938063601046 58221.90110550595 68827.9209971354 68805.5849409204 68857.16215529719 65016.68966822822 85545.9780868883 63375.38858350562 77264.77133847283 0.6702289125437711 0.4104449869485353 0.7535374802373257 0.8908059883542757 0.890516903745235 0.8911844423075489 0.8414790925014248 1.1071795930403792 0.820236538407366 1.0 16.237523150748693 -5.5383350031649305 3.115643532939529 0.9190703728024667 0.5407169090480598 0.7026720586628046 0.0982104426530324 0.12312814296044253 2.4457268269830847 0.026050409102634113 0.0544269849950487 2.89510951599757e-06 5.5383350031649305 -0.3783534637544069 TLPS(ph)PIDAK ddPTM_PC-9_Lapatinib_30min_R1 1 TLPSPIDAK 9 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 T(0.039)LPS(0.961)PIDAK 89.561 0.0092508 5055000.0 68076.0 53764.0 51934.0 47751.0 66449.0 53449.0 51436.0 46412.0 52026.0 50274.0 True False 67105.22375639048 53639.512761250335 47664.18699103736 51262.76783266635 62540.60046376041 51163.11086570445 54099.10440171911 48568.4709553361 46166.28402193238 58963.79391410582 1.1380750677974436 0.9097025343957427 0.8083636385486166 0.8693939862035037 1.0606610652439532 0.8677038478941019 0.9174970063922067 0.8236998966872302 0.7829598632880386 1.0 15.847541734460256 -7.258254248636981 2.1536486161055737 0.8590651040982721 0.9402402756369923 0.08673938414957882 0.10451938396056912 0.8190324792559067 7.431092637237906 0.05271682234432479 0.03416885228398762 5.5175433165805355e-08 7.258254248636981 0.08117517153872023 TLPS(ph)TSSSGSK ddPTM_PC-9_AZD4547_30min_R2 2 TLPSTSSSGSK 11 0 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 TLPS(0.849)T(0.013)S(0.061)S(0.061)S(0.013)GS(0.002)K;T(0.04)LPS(0.872)T(0.023)S(0.023)S(0.04)S(0.001)GS(0.001)K 105.03 0.0026088 18961700.0 72612.0 88094.0 99876.0 118244.0 105629.0 104110.0 93788.0 105342.0 90146.0 91755.0 True False 95701.10557657461 116568.6627279372 98551.57898218078 90984.67265158908 90964.23663925966 97599.98524198134 102134.95030856942 89063.8144183432 94910.93352329342 88542.68537804834 1.0808471097071675 1.316525043601593 1.113040321302632 1.027579774242381 1.0273489701703997 1.1022930333009586 1.1535108730042074 1.0058856249736476 1.0719229162528192 1.0 16.434085508608035 -5.512297097142739 22.613632601846305 1.06135697147841 1.2027102823063465 0.4055191559784892 0.06871925936457149 124.5841769841855 266241.6669328341 0.01759789205148433 0.033270710705091404 3.073993202817593e-06 5.512297097142739 0.14135331082793656 TLPS(ph)TSSSGSKR ddPTM_PC-9_AZD4547_30min_R2 1 TLPSTSSSGSKR 12 1 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 T(0.005)LPS(0.933)T(0.05)S(0.011)SSGSKR 60.937 0.026543999999999998 7928700.0 16154.0 15809.0 26753.0 35041.0 27361.0 25967.0 17018.0 20791.0 19388.0 22755.0 True False 21290.635975926663 20918.95008815536 26398.237739900334 26962.83882805326 23562.397435238247 24343.279385059315 18532.569031765597 17578.228679650776 20412.810098613514 21958.354376082963 0.9695916010498683 0.9526647457215773 1.2021956330504115 1.2279079919313616 1.0730493292749845 1.1086112815254503 0.8439871547000475 0.8005257761390799 0.9296147493114122 1.0 14.422482318117318 -7.258530834098211 24.66309487323143 0.876909061575931 1.0935399821957663 0.49974786941752614 0.09516532499264674 178.33732505796064 1512225.8373686415 0.04050244064487735 0.029967361312412635 5.5140305240367507e-08 7.258530834098211 0.21663092061983535 TLPSTSSSGS(ph)KR ddPTM_PC-9_Lapatinib_30min_R1 1 TLPSTSSSGSKR 12 1 A0A286YEX4;P08651-2;P08651;P08651-5;P08651-3;P08651-6;P08651-4 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 TLPS(0.006)T(0.005)S(0.163)S(0.163)S(0.135)GS(0.528)KR 52.599 0.043532 5750600.0 18319.0 16030.0 16251.0 12810.0 18991.0 22671.0 18599.0 15294.0 22614.0 15174.0 True False 18057.76770070684 15992.88351988027 14914.905510674103 13752.090132907288 17873.98671774255 21701.41417868223 19561.96521439407 16004.615073491981 20066.973184022958 17796.805681915932 1.014663419012103 0.8986378682625781 0.8380664360363137 0.7727280040418351 1.004336791512257 1.2193994004628557 1.0991840650522913 0.8992970626046072 1.1275603916052102 1.0 14.119330697122388 -6.511669183618468 24.665500478738288 1.0699188935667248 0.8803784979207349 0.46098037539525816 0.09605657678146247 430.6025205336158 947499.3993210351 0.03199692558309669 0.03421232058730062 3.078440871450772e-07 6.511669183618468 -0.1895403956459899 TLQPPES(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 TLQPPESPR 9 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 TLQPPES(1)PR;TLQPPES(1)PR;TLQPPES(1)PR 124.12 0.0014688 63014000.0 85427.0 106670.0 160322.0 229075.0 189944.0 188474.0 159015.0 218557.0 160814.0 190014.0 True False 112591.00900801594 141148.9914544583 158196.02552746626 176265.29792346968 163573.55427209885 176688.6909854688 173167.02694712734 184784.0375902279 169314.29973171203 183361.66769576055 0.6140378761979329 0.7697846187168037 0.8627540724048719 0.9612985098714013 0.8920815147880594 0.9636075697055517 0.9444014614573178 1.0077571823617322 0.9233898331064683 1.0 17.484332545183655 -4.179977030001763 0.707164296582031 0.9655838942309163 7.16890572089726e-20 0.9249904325635582 0.03143565279867875 1.454923141182461 0.30020082989591584 0.01217008379492634 1.3647402166147178 6.607283932562948e-05 4.179977030001763 -0.9655838942309163 TLQPPES(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLQPPESPR 9 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 TLQPPES(1)PR 117.09 0.0018789999999999998 14874000.0 56391.0 65822.0 101810.0 113140.0 122580.0 72009.0 93842.0 87886.0 75813.0 68348.0 True False 65936.88252698144 72356.37315755647 104237.53651657514 106801.13260482906 98561.32894789259 68232.72127540031 84952.60640275502 85579.08562291434 76921.62170089524 80738.95135752954 0.8166675615465782 0.8961767764006099 1.2910439727534828 1.3227956371626695 1.2207407613140986 0.8451028918278993 1.0521886273524472 1.0599479456198488 0.952720098633306 1.0 16.300977228677553 -6.749184827276054 24.999319719838546 0.9901259278792897 1.1195716686870754 0.13552569854261165 0.15932653222563004 538.1057112581307 1097734.9461286815 0.05911605553016466 0.05870633786243478 1.781620383134716e-07 6.749184827276054 0.1294457408077857 TLQPPES(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 TLQPPESPR 9 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 TLQPPES(1)PR;TLQPPES(1)PR;T(0.001)LQPPES(0.999)PR 117.09 0.0018789999999999998 57592000.0 187702.0 161959.0 171712.0 151078.0 162401.0 138065.0 130667.0 126025.0 166811.0 112515.0 True False 185025.3350596691 161583.99388623156 157594.50218748802 162188.7801014342 152848.89247265077 132160.2817952345 137432.2979014587 131880.58157688158 148022.98858229665 131963.0678331867 1.4020993759675087 1.2244637574695398 1.194231876957436 1.2290467534936027 1.1582702265293319 1.0014944633016345 1.0414451570282193 0.999374929230886 1.1217001166524192 1.0 17.00977469713309 -2.764149905060307 0.2974092169526396 1.0007300706686046 2.5844841943429335 0.8109165703109826 0.054235183326685595 11.308450834944125 0.31128074989933524 0.060353380430219226 8.212970397208284 0.0017212743416225378 2.764149905060307 1.5837541236743289 TLQPSS(ph)QNTK ddPTM_PC-9_AZD4547_30min_R2 1 TLQPSSQNTK 10 0 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 T(0.001)LQPS(0.172)S(0.825)QNT(0.001)K 96.604 0.014098 0.0 15237.0 19612.0 20669.0 26051.0 22843.0 23994.0 18992.0 22810.0 22328.0 25755.0 True False 20082.04905071157 25951.195466437013 20394.915555115313 20045.344433937826 19671.643748881535 22493.65138695703 20682.251207620884 19285.238621655244 23508.21249648456 24853.325289211884 0.8080226214006304 1.044173975291012 0.8206111382595617 0.8065457720717532 0.7915095271947546 0.9050560086106819 0.8321723941141372 0.7759621055628485 0.9458779548782875 1.0 14.601151271872418 -8.484731418050892 6.389162457036374 0.9998925648332866 0.8519628171905465 0.3251216366406978 0.0738788450322547 0.20922081727830993 24.35281181200596 0.07241716787875098 0.01875547087630258 3.275431957089166e-09 8.484731418050892 -0.14792974764274014 TLQQQTFK ddPTM_PC-9_Lapatinib_30min_R1 2 TLQQQTFK 8 0 A0A494C0B4;P54725-2;P54725-3;P54725;K7ENJ0;K7ELW1;Q5W0S5;P54727 A0A494C0B4;P54727 RAD23A;RAD23B UV excision repair protein RAD23 homolog A;UV excision repair protein RAD23 homolog B 0 ; 126.07 0.016087 3713800.0 32497.0 33389.0 26367.0 29071.0 31758.0 27048.0 26221.0 23962.0 28429.0 28250.0 False True 32033.586820780056 33311.68982191405 24199.207039563353 31208.978318013094 29890.056878630316 25891.220091967574 27578.59507966164 25075.36199758172 25227.026649358293 33132.97485924114 0.9668189155024076 1.0053938701077143 0.7303662632881254 0.9419310656709287 0.9021241529205356 0.7814336081188387 0.8323609696027544 0.7568098579771183 0.7613873114783777 1.0 15.015980121815268 -6.746608680057093 22.328255420171224 0.8115716554252072 0.9065331235257633 0.15417490370774456 0.09384993627451424 112.65538303323831 169605.6039713026 0.030592970384921852 0.030420734782350266 1.792220002007463e-07 6.746608680057093 0.09496146810055617 TLQRLS(ph)SGFDDIDLPSAVK ddPTM_PC-9_AZD4547_30min_R2 2 TLQRLSSGFDDIDLPSAVK 19 1 Q9Y446;Q9Y446-2;E9PKC4 Q9Y446 PKP3 Plakophilin-3 1 T(0.317)LQRLS(0.533)S(0.149)GFDDIDLPSAVK;T(0.017)LQRLS(0.726)S(0.257)GFDDIDLPSAVK 94.01899999999999 0.00037048 22150000.0 76395.0 60357.0 113545.0 203488.0 180567.0 130920.0 83238.0 108768.0 98883.0 136869.0 True False 100687.02088528634 79866.21990453494 112039.31911101489 156576.98545826026 155498.3888632968 122733.55170377677 90646.02074662728 91960.40483999118 104109.75350635457 132077.2579696812 0.7623342764156975 0.6046932010268453 0.8482862290852063 1.1854954279426595 1.177329021314116 0.9292557522049003 0.6863105892721925 0.6962622199584202 0.788248901489561 1.0 17.011022548599783 -10.954471131237947 9.185764744538535 1.0000008548762576 0.857714096968624 0.0523216587007137 0.1865983821746186 3.7670533986737504e-06 2.3319556787569073e-07 0.20833575033309298 0.050528538007058026 1.1105263526554012e-11 10.954471131237947 -0.14228675790763357 TLQRLS(ph)SGFDDIDLPSAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TLQRLSSGFDDIDLPSAVK 19 1 Q9Y446;Q9Y446-2;E9PKC4 Q9Y446 PKP3 Plakophilin-3 1 T(0.014)LQRLS(0.493)S(0.493)GFDDIDLPSAVK;T(0.119)LQRLS(0.825)S(0.055)GFDDIDLPSAVK;T(0.185)LQRLS(0.741)S(0.074)GFDDIDLPSAVK 78.428 0.0021756999999999996 15884700.0 52275.8 44868.6 64209.9 96348.0 111981.0 132630.0 128163.0 130509.0 126906.0 105834.0 True False 61125.06044588635 49322.85808175292 65740.90753340184 90949.93392443068 90039.12691233476 125674.64931822903 116022.47282023319 127083.27703571557 128761.76016743577 125020.86641851706 0.4889188676813794 0.3945170073981156 0.525839481173719 0.7274780325067394 0.7201927925449003 1.0052293902485316 0.9280248661198599 1.0164965311494036 1.0299221550456688 1.0 16.931809380253412 -6.183339462065809 0.8711404799413605 1.0173474278282115 0.4086540209461625 0.9404210190456731 0.056907372364514305 0.13199254337516494 0.21162518083109347 0.027260301670514804 0.049555866016248916 6.556325971126659e-07 6.183339462065809 -0.6086934068820491 down TLQRLS(ph)SGFDDIDLPSAVK ddPTM_PC-9_Lapatinib_30min_R1 2 TLQRLSSGFDDIDLPSAVK 19 1 Q9Y446;Q9Y446-2;E9PKC4 Q9Y446 PKP3 Plakophilin-3 1 T(0.012)LQRLS(0.743)S(0.246)GFDDIDLPSAVK;T(0.044)LQRLS(0.478)S(0.478)GFDDIDLPS(0.001)AVK 78.45100000000001 0.0014611 13895000.0 102773.0 56880.0 88157.0 73464.0 79651.0 88103.0 62623.0 55767.0 95825.0 50014.0 True False 101307.4381737398 56748.29785469679 80909.07175586086 78866.78762871998 74966.0847798911 84335.04006812409 65865.31252330761 58358.13840744262 85032.17941801542 58658.85326053405 1.7270613478204477 0.9674293768179971 1.3793156064013419 1.3444993082021588 1.2780011986754714 1.4377205720941888 1.1228537358336341 0.9948734958769855 1.4496052120273117 1.0 15.840061247243163 -10.00326878027591 0.039965027557092477 1.9633311399586705e-10 2.2118513215087625 0.20114292718712878 0.20935499836252175 453.0275215994737 4.311805156180507 142.21583629899155 97.55938391623474 9.925016095238743e-11 10.00326878027591 2.2118513213124293 TLQTDSIDSFET(ph)QRTPR ddPTM_PC-9_AZD4547_30min_R2 1 TLQTDSIDSFETQRTPR 17 1 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 TLQTDSIDS(0.011)FET(0.495)QRT(0.495)PR 70.167 0.010877 55202000.0 62236.0 46564.0 70018.0 79391.0 81151.0 91168.0 58288.0 77610.0 59942.0 77397.0 True False 82025.75341078208 61614.902391350864 69089.5155710515 61088.631528722864 69884.58441822363 85467.250547891 63475.51908118191 65617.15780037975 63110.41174598162 74687.35458781329 1.0982549035706 0.8249710105732484 0.925049708245053 0.8179246924176194 0.9356950022383934 1.1443336160394235 0.8498830817009443 0.8785577982043895 0.8449946057706444 1.0 16.188576378684743 -10.642060500043083 4.714358225181995 1.0000026546435294 0.9216296523242343 0.04261594698765958 0.10675971281368216 6.175057053915691e-06 1.1537933405304017e-06 0.10312358628289177 0.025009383123728156 2.28002442765913e-11 10.642060500043083 -0.07837300231929512 TLQTDSIDSFETQRT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 TLQTDSIDSFETQRTPR 17 1 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 TLQTDSIDSFET(0.002)QRT(0.998)PR;TLQTDSIDSFET(0.001)QRT(0.999)PR;TLQTDSIDSFETQRT(1)PR 180.7 1.2777e-06 468441000.0 325777.0 302692.0 417010.0 567850.0 539134.0 433871.0 357594.0 469080.0 388394.0 478768.0 True False 429367.30941744795 400531.2695353227 411480.1749305064 436940.9556950445 464284.5502302447 406740.97778238123 389419.1732486296 396594.46438605984 408923.7139179337 462006.4780456381 0.929353439444704 0.8669386438684464 0.8906372409995934 0.9457463833480759 1.0049308230357357 0.8803793823475401 0.8428868246521899 0.8584175400823779 0.8851038531921607 1.0 18.817553555036575 -9.688384088313668 14.573976403574887 0.9999997954777299 0.9000917420954833 0.30050019974903464 0.0455441513685967 0.0 0.0 0.04908277429980327 0.01190432134332005 2.0493489410753824e-10 9.688384088313668 -0.09990805338224662 TLQTDSIDSFETQRT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 TLQTDSIDSFETQRTPR 17 1 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 TLQTDSIDS(0.002)FET(0.047)QRT(0.951)PR;TLQTDSIDSFET(0.058)QRT(0.942)PR;TLQTDSIDSFETQRT(1)PR;TLQTDSIDSFET(0.015)QRT(0.985)PR;TLQTDSIDSFET(0.005)QRT(0.995)PR;TLQTDSIDSFET(0.001)QRT(0.999)PR;TLQTDSIDS(0.125)FET(0.085)QRT(0.789)PR 125.39 2.7803e-05 461142400.0 242673.0 195761.5 255312.0 287174.0 306648.0 286259.0 298094.2 307108.0 272962.8 233992.0 True False 283752.7458897732 215195.40797731766 261399.60635615236 271084.5718106701 246562.52569108625 271247.07410983095 269856.5593608852 299046.7404078227 276954.36455511645 276412.8973203474 1.02655392943159 0.7785288243186351 0.9456852733365931 0.9807233108102693 0.8920080360987419 0.9813112077598553 0.976280636601903 1.0818841787300684 1.0019589072724835 1.0 18.076465407333764 -7.164857504908845 1.6858234769970268 1.029047229775798 0.9204047945734583 0.2936556180761989 0.06571187598101189 0.43476965281393243 2.4321851029706276 0.03331041290524516 0.02206672714375091 6.841360803470414e-08 7.164857504908845 -0.10864243520233974 TLQTDSIDSFETQRT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 5 TLQTDSIDSFETQRTPR 17 1 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 TLQTDSIDSFET(0.007)QRT(0.993)PR;TLQTDSIDSFET(0.001)QRT(0.999)PR;TLQTDSIDSFETQRT(1)PR;TLQTDSIDSFET(0.002)QRT(0.998)PR;TLQTDSIDS(0.002)FET(0.057)QRT(0.942)PR 149.97 2.9956e-05 512533700.0 381606.0 355180.0 459813.0 423290.0 366542.0 360762.0 317223.0 313559.0 449983.0 288944.0 True False 376164.2284620309 354357.60253219464 422008.95006950817 454420.1586540453 344982.72020929906 345333.05023729656 333647.2547559402 328128.0958434078 399301.1760089414 338887.58540632046 1.1099970747261703 1.0456494064464648 1.2452771014421393 1.3409171011950858 1.0179857128601233 1.0190194775746892 0.9845366697511294 0.9682505644164798 1.178270297302824 1.0 18.370447261448177 -6.3618389563966025 24.999572895154607 1.0237983811769622 1.1797693205548367 0.41883760485226484 0.09067963831598458 42.8396391026207 10658.734083193394 0.029793966457424804 0.03378319343173301 4.346713776531301e-07 6.3618389563966025 0.15597093937787454 TLS(ph)ADASVNTLPVVVSR ddPTM_PC-9_AZD4547_30min_R2 3 TLSADASVNTLPVVVSR 17 0 Q92615;H0Y4V9;H0Y641 Q92615 LARP4B La-related protein 4B 1 T(0.112)LS(0.888)ADASVNTLPVVVSR;T(0.173)LS(0.827)ADASVNTLPVVVSR;T(0.004)LS(0.991)ADAS(0.005)VNTLPVVVSR 178.06 3.6276e-06 31253900.0 67003.0 71921.0 89990.0 114646.0 90991.0 96590.0 85042.0 91652.0 77792.0 87263.0 True False 88308.56025102249 95168.05675818963 88796.67380157852 88216.13596304301 78358.47026898744 90550.21203076537 92610.57325181636 77489.28935343925 81903.92630448444 84207.94893079015 1.0486962498469425 1.1301552640405421 1.054492775670855 1.0475986778344066 0.9305353148238968 1.0753166794881546 1.099784217852548 0.9202134755369363 0.9726388938863791 1.0 16.361668804548373 -5.685767309332179 0.4060115294001887 0.9816804847589241 1.1268364627809002 0.24661996289773824 0.057776067514523625 4.130698137547678 0.9126488751864127 0.055804947754442946 0.27272965536600496 2.0617342741274265e-06 5.685767309332179 0.1451559780219761 TLS(ph)ADASVNTLPVVVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLSADASVNTLPVVVSR 17 0 Q92615;H0Y4V9;H0Y641 Q92615 LARP4B La-related protein 4B 1 T(0.015)LS(0.983)ADAS(0.002)VNTLPVVVSR;TLS(0.996)ADAS(0.004)VNTLPVVVSR 180.76 1.7303e-06 13216100.0 19285.4 27137.4 25836.1 25633.9 35145.0 25331.0 35843.0 31977.0 29311.0 25991.0 True False 22550.037315987454 29831.421727171404 26452.130607954885 24197.715689225093 28258.589540493456 24002.597767323066 32447.69155915213 31137.63763243211 29739.617924035938 30702.962555357226 0.7344580274730784 0.971613787216317 0.8615497791218641 0.7881231540961815 0.920386411882678 0.7817681347214149 1.0568260799148996 1.014157431104284 0.9686237238642889 1.0 14.906090248751143 -7.266499380197291 24.990915854886435 1.0110815986489843 0.8506986818635733 0.592178437669064 0.06767650797822977 309.1474230631738 1526845.4315431656 0.026624319226765298 0.018573814130618486 5.413780205089536e-08 7.266499380197291 -0.16038291678541094 TLS(ph)ADASVNTLPVVVSR ddPTM_PC-9_Lapatinib_30min_R1 4 TLSADASVNTLPVVVSR 17 0 Q92615;H0Y4V9;H0Y641 Q92615 LARP4B La-related protein 4B 1 T(0.123)LS(0.877)ADASVNTLPVVVSR;T(0.059)LS(0.934)ADAS(0.007)VNTLPVVVSR;T(0.004)LS(0.995)ADAS(0.001)VNTLPVVVSR;T(0.001)LS(0.999)ADASVNTLPVVVSR 185.59 3.1348e-08 19563700.0 55346.7 44683.3 56160.1 46190.1 63234.6 72100.2 65964.2 57816.2 68363.2 70310.1 True False 54557.445908658316 44579.83856418377 51542.83336225514 49587.074039656596 59515.26515200695 69016.64251977518 69379.50351069061 60502.55172041502 60663.41651958952 82463.10710268085 0.661598232537186 0.540603430194234 0.6250411265497842 0.6013243471157605 0.7217198968491466 0.8369396320931433 0.8413399148821923 0.7336923606950544 0.735643109397431 1.0 16.331461200673303 -6.458019259271334 2.779974331607403 0.8133249928968673 0.6027074663482441 0.6549236902829989 0.07545012128417222 0.1782725062841386 2.716138838679511 0.025106590224006565 0.02790594472078929 3.4832186797325825e-07 6.458019259271334 -0.2106175265486232 TLS(ph)ASTQDLSPH ddPTM_PC-9_AZD4547_30min_R2 2 TLSASTQDLSPH 12 0 Q6P597;Q6P597-3;Q6P597-2 Q6P597 KLC3 Kinesin light chain 3 1 T(0.067)LS(0.841)AS(0.082)T(0.009)QDLSPH;T(0.076)LS(0.919)AS(0.005)T(0.001)QDLSPH 182.23 0.00020004 11025500.0 31942.0 28854.0 56242.0 63912.0 48195.0 43069.0 39425.0 44641.0 37664.0 43753.0 True False 42098.89156512629 38180.49122927664 55496.19433212999 49178.07583055675 41503.95615625555 40375.88862152425 42933.74862365487 37742.75919812853 39654.84214742005 42221.220787376755 0.9971026602270334 0.9042962405457445 1.3144147255145728 1.1647715275267443 0.9830117505428537 0.9562937278591381 1.0168760595499207 0.8939286570655676 0.9392159063121169 1.0 15.365680673024478 -6.402125879847385 5.928375504790315 0.959368090783201 1.0966148751365004 0.27391116961716555 0.10426283416762597 0.34247328851876735 15.268975872024738 0.035252536090077904 0.03993698336605294 3.96163190084215e-07 6.402125879847385 0.1372467843532994 TLS(ph)ASTQDLSPH ddPTM_PC-9_Lapatinib_30min_R1 1 TLSASTQDLSPH 12 0 Q6P597;Q6P597-3;Q6P597-2 Q6P597 KLC3 Kinesin light chain 3 1 T(0.017)LS(0.95)AS(0.028)T(0.004)QDLS(0.001)PH 158.34 8.9074e-12 0.0 3478.3 2702.1 6105.6 4692.0 11538.0 15101.0 16739.0 18328.0 22428.0 19807.0 True False 3428.698804157902 2695.8434534665294 5603.621136297566 5037.065332053166 10859.357524580782 14455.165432150341 17605.663515443975 19179.585789653534 19901.922462689796 23230.61355883148 0.14759398392447662 0.1160470190182154 0.24121709579931705 0.21682876861159125 0.4674589199755522 0.6222463903307016 0.7578647662859903 0.8256168413753375 0.8567110124873896 1.0 14.503739638155656 -6.763400250067243 0.6823458587650104 0.946581465684838 0.09494135153539199 0.9847688247267211 0.03859942505308181 0.07922089280809472 0.08095284059923012 0.028712024963321606 0.02969977979557043 1.7242480755174064e-07 6.763400250067243 -0.8516401141494461 down TLS(ph)DDLDEAAKEFQEK ddPTM_PC-9_AZD4547_30min_R2 3 TLSDDLDEAAKEFQEK 16 1 A0A087WV29;Q9H0A0-2;Q9H0A0 A0A087WV29 NAT10 N-acetyltransferase 10 1 T(0.075)LS(0.925)DDLDEAAKEFQEK;T(0.044)LS(0.956)DDLDEAAKEFQEK;T(0.209)LS(0.791)DDLDEAAKEFQEK 65.92399999999999 0.013028999999999999 7639100.0 47702.299999999996 42138.3 44412.0 60538.0 57773.0 51307.2 46216.1 51132.3 47785.0 57830.8 True False 62870.63913052167 55758.681415631436 43823.06786171469 46581.8994027764 49752.216184569996 48098.95267320506 50329.243367551004 43230.9779383631 50310.81754498904 55806.16129432555 1.126589567752879 0.9991492000597622 0.7852729312555436 0.8347088981286536 0.8915183383098753 0.8618932310991229 0.9018581855525073 0.7746631722321831 0.9015280101357682 1.0 15.768136791533337 -4.999868623026518 3.666512408587639 0.8617652236970328 1.115495515559703 0.6371999447068821 0.06179145481750582 0.12469085245284284 3.583764755736206 0.015031619911464192 0.06440145144105021 1.000302552420457e-05 4.999868623026518 0.25373029186267027 TLS(ph)DDLDEAAKEFQEK ddPTM_PC-9_Lapatinib_30min_R1 1 TLSDDLDEAAKEFQEK 16 1 A0A087WV29;Q9H0A0-2;Q9H0A0 A0A087WV29 NAT10 N-acetyltransferase 10 1 T(0.229)LS(0.771)DDLDEAAKEFQEK 55.18899999999999 0.031417 1860000.0 12813.0 8721.6 7155.5 6710.1 7217.5 8528.8 7387.0 6631.7 8794.8 5575.5 True False 12630.284270383578 8701.405671053511 6567.202411028765 7203.583138237411 6792.98084015096 8164.043105603854 7769.462715131404 6939.832992211114 7804.237010650271 6539.2177461132405 1.9314671510809875 1.330649323648142 1.0042795126270505 1.1015970744389194 1.0388063379887527 1.2484739647118146 1.1881333542914048 1.0612634816046598 1.1934511609265388 1.0 12.674902348320908 -4.797357532233238 2.849264602648403 1.1132049232775254 2.061953922530693 0.9044936048465224 0.08099618241587053 0.1100771023482226 1.2800832749975357 0.020878477516121995 0.2423131102975345 1.5945658829428374e-05 4.797357532233238 0.9487489992531677 TLS(ph)DESIYNSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TLSDESIYNSQR 12 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 T(0.006)LS(0.822)DES(0.172)IYNSQR;T(0.213)LS(0.574)DES(0.213)IYNSQR;T(0.078)LS(0.922)DESIYNSQR 155.86 0.00034048 152579000.0 48735.2 49489.1 47597.0 52032.9 57767.0 43824.7 52344.3 49972.1 41543.0 41254.6 True False 56985.106795923944 54402.050785932246 48731.89299262773 49117.665305937895 46447.97103387926 41526.45558302489 47385.86896408578 48660.38532481662 42150.48778336546 48733.73240876609 1.1693154613717545 1.1163120101210748 0.9999622557918828 1.0078781755099624 0.9530969359023346 0.8521090737461189 0.9723422898666004 0.9984949422027796 0.8649140071976829 1.0 15.572633099133032 -5.16652982218385 1.0239161773955967 0.9389974480573657 1.2211474754415104 0.7196194395369391 0.04879406587974363 0.5804583370684098 0.7473042759237907 0.01686037268904144 0.15628651227764548 6.81506775333625e-06 5.16652982218385 0.28215002738414463 TLS(ph)DESLCSGR ddPTM_PC-9_AZD4547_30min_R2 3 TLSDESLCSGR 11 0 O60292;M0R2Q7 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 T(0.194)LS(0.753)DES(0.051)LCS(0.002)GR;T(0.007)LS(0.968)DES(0.025)LCSGR;TLS(0.999)DESLCSGR 174.21 0.0026726999999999996 109983000.0 80235.4 74761.4 96352.4 115742.0 108743.0 99900.0 83162.0 97337.0 81936.0 88964.0 True False 105748.58820000435 98926.56051114047 95074.70422046022 89059.47009607429 93645.91149081232 93653.2372075104 90563.25689385895 82295.80323174286 86266.96968434069 85849.3974385342 1.2317918512557693 1.1523267892703517 1.1074591908292786 1.0373919066798158 1.0908161767572127 1.0909015089426055 1.054908474560928 0.9586066494021043 1.0048640090468364 1.0 16.38952038779562 -1.522878745287742 0.279377404687362 0.9906548441520944 2.76175099437543 0.81929472217797 0.032370155837922236 23.36968780944142 0.3292348131398215 0.040226635992655455 20.188636067076835 0.029999999999488526 1.522878745287742 1.7710961502233358 TLS(ph)DESLCSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLSDESLCSGR 11 0 O60292;M0R2Q7 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 T(0.112)LS(0.656)DES(0.233)LCSGR;T(0.003)LS(0.972)DES(0.025)LCSGR 120.53 0.00085749 11521200.0 21638.7 21380.3 25242.0 29707.0 34110.0 37351.0 26991.0 30360.0 28026.0 25876.0 True False 25301.7045261938 23502.794886519798 25843.86501081809 28042.61310139347 27426.3903606838 35392.24780732242 24434.217082082283 29563.082169078974 28435.82723001711 30567.113965696695 0.8277426699356737 0.7688915254771949 0.8454793946141211 0.9174112130070148 0.897251549212742 1.1578537590117481 0.799362907126367 0.9671532026954042 0.9302751729171626 1.0 14.899692724252903 -5.786032714372047 1.8251092066530359 0.9581805651553876 0.7968989074115947 0.3723792433666221 0.08550705135072673 0.3754180002555308 2.5514840049503316 0.026406318380801028 0.05288843661817165 1.6366932285697666e-06 5.786032714372047 -0.16128165774379288 TLS(ph)DESLCSGR ddPTM_PC-9_Lapatinib_30min_R1 2 TLSDESLCSGR 11 0 O60292;M0R2Q7 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 T(0.344)LS(0.633)DES(0.023)LCSGR;T(0.076)LS(0.907)DES(0.017)LCSGR 171.49 0.0015757 64086300.0 66340.0 57150.0 57853.0 57900.0 64195.0 65963.0 57136.0 58446.0 71862.0 55360.0 True False 65393.97943473399 57017.672686285536 53096.54965903812 62158.159148737876 60419.17631222598 63141.916257263285 60094.222511404936 61161.61452761299 63768.144819592264 64928.90223743681 1.0071628686343173 0.878155501193892 0.8177644751311325 0.9573265064829424 0.9305436289571117 0.972477803896349 0.9255388654446666 0.9419782626842 0.9821226391045423 1.0 15.98657319726208 TLS(ph)ESFSR ddPTM_PC-9_AZD4547_30min_R2 2 TLSESFSR 8 0 O94921 O94921 CDK14 Cyclin-dependent kinase 14 1 T(0.003)LS(0.822)ES(0.175)FSR;T(0.026)LS(0.808)ES(0.166)FSR 77.533 0.023407 7401800.0 32012.0 28976.0 45872.0 79113.0 61659.0 55999.0 43045.0 75865.0 51264.0 58811.0 True False 42191.15010903579 38341.92534343663 45263.70730776767 60874.72013366569 53098.71216181263 52497.373677511314 46875.92161078564 64141.80745426898 53973.71038246978 56752.04479067521 0.7434296026628474 0.6756042973404282 0.7975696289837444 1.0726436440871265 0.9356264141259127 0.9250305230612066 0.8259776680062056 1.1302113904591498 0.9510443294430524 1.0 15.792384753560427 -5.58400394963002 5.3379303482757186 0.9717570507508076 0.7149086425061699 0.6595676479064746 0.07996184294807175 0.11437784478262635 6.4682097491515265 0.02218782723803987 0.03959678814457496 2.6061298488101372e-06 5.58400394963002 -0.2568484082446377 TLS(ph)ESFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLSESFSR 8 0 O94921 O94921 CDK14 Cyclin-dependent kinase 14 1 T(0.002)LS(0.812)ES(0.187)FSR;T(0.001)LS(0.908)ES(0.091)FSR 96.665 0.0060501999999999995 12508300.0 37126.0 34755.0 41003.0 37987.0 46856.0 38740.0 37309.0 47893.0 32928.0 28903.0 True False 43410.698528075685 38205.24671220685 41980.66702474343 35858.711545515645 37674.903158610396 36708.40620212766 33774.82142623124 46635.85949682807 33409.50970634423 34142.88510397787 1.27144201188253 1.1189812048940084 1.2295582783029784 1.0502542897682035 1.1034481428232035 1.0751407237653414 0.9892199011118792 1.3659027160359887 0.9785204034339736 1.0 15.059297352072578 -1.5228799797521588 0.6402538182952069 1.09479228821991 14.742585198541612 0.19129491091354622 0.1116147220700793 386.44399878530885 2.5877115929942724 0.04577726156016094 7458.395547819704 0.029999914725828795 1.5228799797521588 13.647792910321701 TLS(ph)ESFSR ddPTM_PC-9_Lapatinib_30min_R1 4 TLSESFSR 8 0 O94921 O94921 CDK14 Cyclin-dependent kinase 14 1 T(0.246)LS(0.543)ES(0.211)FSR;T(0.046)LS(0.786)ES(0.167)FS(0.001)R;T(0.008)LS(0.806)ES(0.186)FSR;T(0.041)LS(0.854)ES(0.104)FS(0.001)R 92.23899999999999 0.0081241 20173400.0 63234.0 64300.0 74821.0 68802.0 73739.0 60824.0 60467.0 59282.6 81922.0 55687.0 True False 62332.271564304625 64151.11730058025 68669.50619741224 73861.92859674372 69401.81699645193 58222.69930766916 63597.68539269671 62037.08601777145 72695.08168309582 65312.42375173671 0.9543708223299118 0.9822192106118925 1.0514003653950488 1.1309016624081367 1.0626127926328333 0.8914490683883244 0.9737456021298796 0.9498512297382293 1.1130360428732795 1.0 15.995069827373023 TLS(ph)FDTSK ddPTM_PC-9_AZD4547_30min_R2 2 TLSFDTSK 8 0 Q7L804;Q7L804-2 Q7L804 RAB11FIP2 Rab11 family-interacting protein 2 1 TLS(1)FDTSK;T(0.006)LS(0.994)FDTSK 105.2 0.003846 16686000.0 89842.0 93185.0 79945.0 116043.0 100703.0 101337.0 99080.0 111854.0 95246.0 100247.0 True False 118409.88717031079 123305.22891800596 78884.87706486504 89291.07919647798 86722.12671031037 95000.38137034515 107897.92805660678 94569.53444921621 100280.5091114372 96737.38304281227 1.2240344264626952 1.274638873199989 0.8154539081334627 0.9230255810926904 0.8964696375126302 0.9820441527584182 1.115369515514548 0.9775903737995821 1.0366262344212565 1.0 16.561785889813855 -5.244177861723639 24.889095069835182 0.9690799093152545 1.2493367130013613 0.6800823651512943 0.07709366662985946 470.0534422090782 677759.6509643589 0.02116108795214093 0.055683951668956226 5.699308140136317e-06 5.244177861723639 0.28025680368610684 TLS(ph)FDTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLSFDTSK 8 0 Q7L804;Q7L804-2 Q7L804 RAB11FIP2 Rab11 family-interacting protein 2 1 T(0.022)LS(0.97)FDT(0.006)S(0.001)K;T(0.011)LS(0.986)FDT(0.002)SK 81.33800000000001 0.018025 10279100.0 76501.0 74523.0 66640.0 82037.0 108944.0 80839.0 72404.0 82305.0 72526.0 68710.0 True False 89451.10833637677 81921.15093465077 68228.95033360721 77440.73285754248 87597.20526104768 76599.6605310737 65545.3689604345 80144.58095935592 73586.55554428817 81166.5790919392 1.1020682322345197 1.009296583041363 0.8406039911614699 0.9540963007671375 1.079227512617285 0.9437340021969826 0.8075413513016212 0.9874086336517197 0.9066115187746798 1.0 16.308598189427464 -6.990522352776544 24.934746791336266 0.9173834549279138 0.9891418143758101 0.14120711412444298 0.08275024957084498 418.6037103826369 1101298.7314237203 0.03028275971044775 0.026671838253048825 1.0220629545142722e-07 6.990522352776544 0.07175835944789621 TLS(ph)FDTSK ddPTM_PC-9_Lapatinib_30min_R1 1 TLSFDTSK 8 0 Q7L804;Q7L804-2 Q7L804 RAB11FIP2 Rab11 family-interacting protein 2 1 T(0.001)LS(0.997)FDT(0.001)SK 107.21 0.0038138000000000004 8488200.0 89595.0 72847.0 71383.0 60177.0 61811.0 56461.0 50893.0 45128.0 67585.0 41989.0 True False 88317.35887028919 72678.32724720622 65514.16528634852 64602.617324587205 58175.3985051016 54046.29464701944 53527.990518638486 47224.81162786365 59972.86559839891 49246.742703174365 1.7933644749380835 1.475799682534567 1.330324843639366 1.3118150313812131 1.181304494710301 1.0974592771094218 1.0869346393378452 0.9589428464843345 1.2178037024676793 1.0 15.587740683988827 -1.5228787452803425 0.3766898696193649 1.0334139348331013 11.617324518729474 0.9128351952429699 0.06981079195368153 17.109544356600388 0.23453687374714283 0.0525853580824812 131.80462606771866 0.02999999999999966 1.5228787452803425 10.583910583896373 TLS(ph)GSGSGSGSSYSGSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLSGSGSGSGSSYSGSSSR 19 0 E7ERS3;Q86VM9 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 TLS(0.482)GS(0.482)GS(0.032)GS(0.002)GS(0.001)S(0.001)YSGSSSR 149.24 2.6989999999999997e-14 0.0 4859.7 5216.9 7168.4 4951.3 9835.0 9674.6 6023.4 8258.2 8197.9 7473.8 True False 5682.351226549836 5734.799354709017 7339.32184230839 4673.894713331184 7907.902351138232 9167.246944840066 5452.8199463604315 8041.431000286166 8317.778778596914 8828.740777431753 0.6436196700978245 0.6495602826360533 0.8312988258834542 0.5293953952390028 0.8956999135542193 1.0383413870609512 0.617621480098166 0.9108242277134099 0.9421251555894616 1.0 13.107991969002146 -3.330935381137966 0.1499833490390234 1.0566429370780077 1.8634626584857987e-11 0.38593245867382175 0.13405705779281457 44.85823743134639 0.7306839620319591 0.5604583857975561 9.485439821626224 0.00046672881992927093 3.330935381137966 -1.056642937059373 TLS(ph)GSGSGSGSSYSGSSSR ddPTM_PC-9_Lapatinib_30min_R1 2 TLSGSGSGSGSSYSGSSSR 19 0 E7ERS3;Q86VM9 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 T(0.094)LS(0.552)GS(0.353)GS(0.001)GSGSSYSGSSSR;T(0.004)LS(0.918)GS(0.077)GSGSGSSYSGSSSR 284.07 2.4689999999999994e-203 3335800.0 9802.400000000001 10043.099999999999 9306.5 10091.5 11784.2 13192.0 10703.6 9961.8 11214.5 10737.3 True False 9662.615978459999 10019.845818996224 8541.35549412888 10833.662574257145 11091.076524628606 12627.808912053992 11257.780034882968 10424.661595338863 9951.404916079668 12593.22799844708 0.7672866702366965 0.795653490926378 0.678249889161234 0.8602768547979188 0.8807175194474594 1.0027459928154383 0.8939550714297564 0.8277990040857172 0.7902187522775586 1.0 13.620360513316335 -5.919659875852757 6.27086101292882 0.8934142355104191 0.7525413840057129 0.4999202584994318 0.06789187263545823 0.19185220802932898 11.87792763710468 0.020061473970668705 0.02998597326787473 1.2032063745912955e-06 5.919659875852757 -0.1408728515047062 TLS(ph)MIEEEIR ddPTM_PC-9_AZD4547_30min_R2 9 TLSMIEEEIR 10 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 T(0.125)LS(0.875)MIEEEIR;T(0.002)LS(0.998)MIEEEIR;T(0.014)LS(0.986)MIEEEIR;T(0.056)LS(0.944)MIEEEIR;T(0.048)LS(0.952)MIEEEIR;T(0.113)LS(0.887)MIEEEIR;T(0.259)LS(0.741)MIEEEIR;T(0.001)LS(0.999)MIEEEIR;T(0.062)LS(0.938)MIEEEIR 151.13 0.00016395 89993300.0 108437.90000000001 98205.7 150345.80000000002 178871.8 168736.9 143964.1 126743.7 146731.69999999998 125669.70000000001 142096.19999999998 True False 142918.8965515624 129948.77200786637 148352.1164577994 137635.6700517616 145310.69404590683 134962.00206872635 138023.64376491884 124057.68732403054 132312.34378222274 137121.45528871744 1.0422796071602223 0.9476910213230413 1.081903019082135 1.0037500678647369 1.0597225192800532 0.9842515293070349 1.0065794844016336 0.9047284909777223 0.9649280887781652 1.0 17.065094800600463 -7.6062706016589425 7.78762465898424 0.951239818471992 1.018487800006325 0.31429739126143885 0.04174089561725115 0.2646347336069311 21.39578735847599 0.018828859816455407 0.010813753892582148 2.4758788980165644e-08 7.6062706016589425 0.06724798153433309 TLS(ph)MIEEEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 TLSMIEEEIR 10 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 T(0.051)LS(0.949)MIEEEIR;T(0.002)LS(0.998)MIEEEIR;T(0.002)LS(0.998)MIEEEIR;T(0.003)LS(0.997)MIEEEIR;T(0.093)LS(0.907)MIEEEIR;T(0.228)LS(0.772)MIEEEIR;T(0.001)LS(0.999)MIEEEIR;T(0.057)LS(0.943)MIEEEIR 108.72 0.0017504 67329600.0 103145.5 99532.40000000001 118375.2 126077.6 158775.19999999998 143330.3 169987.09999999998 167705.19999999998 145550.1 118167.4 True False 120605.99593351374 109413.3188852845 121197.7137084461 119013.88082109444 127664.33933730997 135813.8067494275 153884.69128797148 163303.11619834698 147678.4948587637 139590.21420737662 0.8640003643402987 0.7838179739644141 0.8682393274960777 0.8525947287700715 0.9145651080358008 0.9729464742253432 1.102403145963791 1.1698751028187566 1.0579430348847452 1.0 17.09083828124701 -6.854669779353617 1.5826513835926108 1.0978962400208194 0.8395731705292497 0.8326676717699275 0.0480443115302172 0.13618114210173096 0.7045623581509721 0.02165713897701419 0.018246430821004078 1.3974305090485386e-07 6.854669779353617 -0.2583230694915697 TLS(ph)MIEEEIR ddPTM_PC-9_Lapatinib_30min_R1 7 TLSMIEEEIR 10 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 T(0.153)LS(0.847)MIEEEIR;T(0.017)LS(0.983)MIEEEIR;T(0.286)LS(0.714)MIEEEIR;T(0.058)LS(0.942)MIEEEIR;T(0.012)LS(0.988)MIEEEIR;T(0.224)LS(0.776)MIEEEIR;T(0.012)LS(0.988)MIEEEIR 158.06 0.00040998 51029200.0 53778.79999999999 45354.299999999996 59690.9 53438.90000000001 66609.2 69535.59999999999 65666.7 65924.4 75000.4 67988.7 True False 53011.904450175934 45249.284904909895 54783.344615537244 57368.97497294458 62691.37781472582 66561.72448340063 69066.60041636923 68987.48829285442 66553.06516277505 79740.45620575169 0.664805632831985 0.5674570607942679 0.6870207072076635 0.7194462848935463 0.786192866177807 0.8347296673554712 0.8661425291844197 0.8651504089072211 0.8346210735370055 1.0 16.283024238758443 -5.2640274909775 0.2228191390214147 1.0052466501073627 0.3201225791242058 0.8874634940569633 0.03966137511972481 2.949388745383934 0.15979968714810353 0.07644198844725207 0.5610143737499441 5.44468186743856e-06 5.2640274909775 -0.685124070983157 TLS(ph)NESEESVK ddPTM_PC-9_AZD4547_30min_R2 2 TLSNESEESVK 11 0 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;S4R3G4;F8WBN2;F6SRV7;Q8NHM5-5 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 T(0.023)LS(0.977)NESEESVK;T(0.011)LS(0.983)NES(0.002)EES(0.004)VK 76.357 0.020703 11485000.0 27378.0 28335.0 35038.0 42758.0 43311.0 38934.0 27753.0 41933.0 31676.0 36988.0 True False 36083.634502223635 37493.73462887484 34573.37322657751 32900.80370451474 37298.01525227895 36499.45082519734 30222.96323531502 35453.21837447914 33350.32869216434 35693.061378271 1.010942550424952 1.050448831819734 0.968630089197809 0.9217702946753649 1.0449654305916445 1.0225923307160547 0.8467461760989201 0.9932804025619986 0.9343644788190442 1.0 15.123356025566197 TLS(ph)NESEESVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLSNESEESVK 11 0 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;S4R3G4;F8WBN2;F6SRV7;Q8NHM5-5 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 T(0.008)LS(0.991)NESEESVK 110.15 0.0019722000000000003 4589400.0 17454.0 16788.0 13161.0 18772.0 20847.0 14430.0 19328.0 15248.0 13804.0 12599.0 True False 20408.617467786265 18454.601691973203 13474.808153370443 17720.26569964514 16762.18000144166 13673.265397436802 17497.111917397884 14847.75615659144 14005.857385397705 14883.09896637088 1.3712612886536988 1.2399703673053788 0.9053765068563648 1.1906301059802789 1.1262560330557942 0.9187109101627451 1.1756363346728729 0.9976253057337522 0.9410578681929518 1.0 13.861387335963144 -5.04778734208627 4.903737638927292 1.0423069964836624 1.3467346664085542 0.5687872467691863 0.09795233670603691 0.12779917522402587 6.9764723224217855 0.02470981704947054 0.0770615596811385 8.958032998531479e-06 5.04778734208627 0.3044276699248918 TLS(ph)NESEESVK ddPTM_PC-9_Lapatinib_30min_R1 1 TLSNESEESVK 11 0 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;S4R3G4;F8WBN2;F6SRV7;Q8NHM5-5 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 T(0.002)LS(0.998)NESEESVK 138.42 0.00010115 6382200.0 28665.0 22414.0 25235.0 17022.0 24810.0 22135.0 21189.0 26106.0 25927.0 20795.0 True False 28256.231843482816 22362.101760112047 23160.275709916983 18273.854663727398 23350.72457833673 21188.337649205205 22286.062741426747 27318.98006463853 23006.828236586323 24389.38804240424 1.1585461592703985 0.9168783456654394 0.9496046259811735 0.7492543327432339 0.9574133035949219 0.8687523283637303 0.9137606364981123 1.120117487865657 0.9433130588018793 1.0 14.573965939271712 -10.912204232403406 9.068468491410876 1.000000152688512 0.947314761678492 0.013608199576853774 0.11047848991288606 3.4621440059285313e-07 2.3377662577509546e-08 0.10860313664985287 0.026340053483839658 1.2240404435935986e-11 10.912204232403406 -0.05268539101002001 TLS(ph)PDQR ddPTM_PC-9_AZD4547_30min_R2 1 TLSPDQR 7 0 A0A1B0GW41;Q8WYH8-2;Q8WYH8;E9PEN0 A0A1B0GW41 ING5 Inhibitor of growth protein 5 1 T(0.119)LS(0.881)PDQR 76.17 0.031649000000000004 5847500.0 35598.0 33011.0 52951.0 78012.0 72958.0 57578.0 46771.0 55730.0 56764.0 54369.0 True False 46917.42351560219 43681.16018471101 52248.8351424312 60027.5386733852 62829.041046749466 53977.63855789835 50933.52839256723 47118.20904799853 59764.42915399725 52465.55785863564 0.8942518755259885 0.8325682975182783 0.9958692383146218 1.1441322864635257 1.1975292670295705 1.0288204445159412 0.9707993295297394 0.8980788725234728 1.1391173865915587 1.0 15.679083024940637 -5.405681938696864 4.422294311182078 1.0524469492376691 0.865498869744687 0.43491191187881717 0.0855203635674287 0.22405283204551196 7.007195930537528 0.02500897650430803 0.05452264485710761 3.929325994313647e-06 5.405681938696864 -0.1869480794929821 TLS(ph)PDQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLSPDQR 7 0 A0A1B0GW41;Q8WYH8-2;Q8WYH8;E9PEN0 A0A1B0GW41 ING5 Inhibitor of growth protein 5 1 T(0.316)LS(0.684)PDQR 75.043 0.033296 4999900.0 35236.0 42414.0 45792.0 40365.0 48240.0 34722.0 39452.0 43613.0 44385.0 27929.0 True False 41200.7588572772 46624.5816156392 46883.85494712705 38103.4799150957 38787.718293737526 32901.117195412386 35714.82095225486 42468.204961793235 45034.046656829676 32992.30661415763 1.2487989802930957 1.413195571952878 1.421054171671898 1.154920156408366 1.1756594877513953 0.9972360399104041 1.082519672538717 1.2872153941358353 1.3649863037313283 1.0 15.0098420251236 -5.770620302574801 24.93681075821371 1.1554267047747773 1.366234174037903 0.40429812935933906 0.11627206634882782 191.74744101444193 520816.4949038242 0.03472943261524391 0.05232777406623346 1.6958197833843035e-06 5.770620302574801 0.21080746926312566 TLS(ph)PDQR ddPTM_PC-9_Lapatinib_30min_R1 1 TLSPDQR 7 0 A0A1B0GW41;Q8WYH8-2;Q8WYH8;E9PEN0 A0A1B0GW41 ING5 Inhibitor of growth protein 5 1 T(0.137)LS(0.863)PDQR 87.476 0.017916 3541000.0 26943.0 24397.0 28952.0 25103.0 25878.0 29236.0 20699.0 20084.0 28191.0 18744.0 True False 26558.787879258936 24340.510245447214 26571.67831795192 26949.15836115313 24355.906918105524 27985.644432444697 21770.69293901516 21017.17596024671 25015.832715609406 21983.875425189945 1.208103092179411 1.1071983339915104 1.2086894509739214 1.225860219817011 1.1078986960687385 1.2730077791642551 0.9903027795576702 0.9560268857857721 1.1379173249383197 1.0 14.424158113601129 -7.275101640477017 24.982037756205607 1.0173973098809341 1.1837236107958595 0.6154796912120359 0.06472907944852803 526.0368701202924 961877.6233401792 0.025957397359276345 0.017608119608439814 5.307602127781789e-08 7.275101640477017 0.1663263009149254 TLS(ph)PEFNER ddPTM_PC-9_AZD4547_30min_R2 1 TLSPEFNER 9 0 Q9BSJ8;Q9BSJ8-2 Q9BSJ8 ESYT1 Extended synaptotagmin-1 1 T(0.289)LS(0.711)PEFNER 95.618 0.005368199999999999 9259700.0 26612.0 32058.0 43365.0 47813.0 42227.0 38936.0 33221.0 47334.0 37618.0 30576.0 True False 35074.06243601339 42420.12157164178 42789.951765812344 36790.4515534862 36364.509941076925 36501.32576488121 36177.604642395425 40019.617927112195 39606.41068133088 29505.543546610075 1.1887278870360984 1.4377000547246477 1.4502343160774793 1.2468996375331338 1.2324636515721767 1.237100604746354 1.226129069110198 1.3563423383098494 1.3423379446904413 1.0 14.848698415239221 -10.855457951655314 3.1325041458722658 0.9975526059627763 1.3041375355125011 0.5201577808380349 0.08699414383911565 22029394.43439502 29225574.927478578 502930.0312312498 0.024071257878577522 1.3948967048500991e-11 10.855457951655314 0.3065849295497248 TLS(ph)PEFNER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLSPEFNER 9 0 Q9BSJ8;Q9BSJ8-2 Q9BSJ8 ESYT1 Extended synaptotagmin-1 1 T(0.187)LS(0.813)PEFNER 105.13 0.0026565 8935100.0 25723.0 33792.0 37246.0 33886.0 46380.0 33136.0 35489.0 25288.0 29738.0 28190.0 True False 30077.395847591728 37146.64643645214 38134.08589624158 31987.47727989428 37292.171941615794 31398.289827405835 32127.2250018902 24624.21679485076 30172.8619912313 33300.623848082796 0.903208179666681 1.115494010139716 1.1451462912589567 0.9605669078699822 1.119864063560563 0.942873922441952 0.9647634575392452 0.7394521167887502 0.9060749771199386 1.0 15.023261584296582 -7.151682680461244 2.053356140399002 0.8726178599320755 1.0518595257288068 0.32967564190584553 0.09576260268754973 0.32885816238154447 2.721086055748685 0.04396215320752257 0.030636532954284063 7.052081447988495e-08 7.151682680461244 0.1792416657967313 TLS(ph)PEFNER ddPTM_PC-9_Lapatinib_30min_R1 1 TLSPEFNER 9 0 Q9BSJ8;Q9BSJ8-2 Q9BSJ8 ESYT1 Extended synaptotagmin-1 1 T(0.209)LS(0.791)PEFNER 135.8 0.0010382 3429700.0 25236.0 24843.0 20042.0 13932.0 17322.0 17340.0 15615.0 16611.0 22104.0 10422.0 True False 24876.13001228439 24785.477559849372 18394.22412435728 14956.605755789567 16303.15401636231 16598.408621514263 16423.468295218216 17382.807701436857 19614.414754561058 12223.428813557925 2.0351188190904668 2.0277025323989233 1.504833414987034 1.2236014938132638 1.3337627489824504 1.3579175593597534 1.3436056728208463 1.4220893307904143 1.6046573390933676 1.0 13.577361414169543 -5.330722618047231 3.371535241090481 1.347037935230688 2.0472344582905397 0.7845051668719976 0.1452028995824792 0.10083473694257064 2.229886469978136 0.037873116273726457 0.0946019295005391 4.669575287865491e-06 5.330722618047231 0.7001965230598517 TLS(ph)PGRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLSPGRR 7 1 Q13523 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 T(0.025)LS(0.975)PGRR;T(0.03)LS(0.97)PGRR 85.676 0.0087671 124522000.0 48321.0 48683.0 49430.0 55911.0 47555.0 52920.0 58548.0 55322.0 46555.0 41460.0 True False 56500.79091674684 53515.92650526155 50608.598664318895 52778.4879359077 38236.939126423866 50144.78203966431 53001.90958918724 53869.856118504205 47235.77880159301 48976.36980282056 1.15363370425819 1.0926887133676362 1.033326864936493 1.0776316854106278 0.7807221988964521 1.0238566525356572 1.0821935109231973 1.0999152516894346 0.9644605958294747 1.0 15.579798222835574 -5.106238604599785 1.4916948258638676 1.004271311443474 1.1661084860736195 0.2516140790343462 0.084969922484101 1.029976942286384 3.236134106270804 0.026674512082834827 0.20643991120960742 7.829993389442143e-06 5.106238604599785 0.16183717463014546 TLS(ph)PSSGYSSQSGTPTLPPK ddPTM_PC-9_AZD4547_30min_R2 1 TLSPSSGYSSQSGTPTLPPK 20 0 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 T(0.046)LS(0.371)PS(0.264)S(0.264)GYS(0.002)S(0.002)QS(0.033)GT(0.018)PTLPPK 194.67 7.157499999999999e-49 0.0 12789.0 15917.0 19806.0 25272.0 25618.0 23331.0 19592.0 24244.0 19540.0 19148.0 True False 16855.63597227474 21061.858976100244 19543.359498989492 19445.9308485078 22061.38289886823 21872.108881766046 21335.65004526689 20497.646871697045 20572.84450829938 18477.634348197607 0.912218288047188 1.1398568983022825 1.057676493143498 1.0524037050448856 1.1939506152756074 1.1837072035089573 1.1546743291490704 1.1093220314588852 1.1133916886014226 1.0 14.173492442981532 -4.757679301000158 24.995312224420836 1.1177088594311586 0.912217994014238 0.511784937076992 0.05817093513526653 90.44602023073578 601157.456968374 0.014817563478017834 0.10822790178961134 1.7471118082392272e-05 4.757679301000158 -0.20549086541692063 TLS(ph)PTPASATAPTSQGIPTSDEESTPKK ddPTM_PC-9_Lapatinib_30min_R1 2 TLSPTPASATAPTSQGIPTSDEESTPKK 28 1 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 T(0.044)LS(0.856)PT(0.062)PAS(0.01)AT(0.027)APTSQGIPTSDEESTPKK;T(0.047)LS(0.64)PT(0.222)PAS(0.09)AT(0.001)APTSQGIPTSDEESTPKK 130.75 1.891e-12 11452500.0 74593.0 54657.0 66748.0 52639.0 61945.0 61150.0 49415.0 47741.0 66770.0 44422.0 True False 73529.29014131929 54530.44507461609 61260.23709473108 56510.24765855635 58301.516888555736 58534.75704761225 51973.46691054803 49959.22114708909 59249.65948072932 52100.28351140569 1.4113030714165387 1.0466439220561707 1.1758138913259486 1.0846437648690577 1.1190249449562493 1.1235016990799664 0.9975659134209913 0.9589049767100043 1.1372233601715145 1.0 15.669003602713236 TLS(ph)PTPSAEGYQDVR ddPTM_PC-9_AZD4547_30min_R2 3 TLSPTPSAEGYQDVR 15 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4;H0Y7N6;F6XFR5 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 TLS(0.935)PT(0.065)PS(0.001)AEGYQDVR;T(0.001)LS(0.994)PT(0.004)PSAEGYQDVR;T(0.015)LS(0.983)PT(0.002)PSAEGYQDVR 146.84 0.00010797 148364000.0 59145.600000000006 60119.5 85638.2 107574.8 109799.0 98105.0 85132.6 89818.0 73160.1 86991.8 True False 77952.67049509524 79551.95267410057 84502.5815129942 82775.09187409218 94555.30411869925 91970.47884126959 92709.23647630075 75938.69191231161 77027.19352669563 83946.24356024331 0.9286022481655557 0.9476535137276367 1.0066273120649127 0.9860487898388132 1.1263792173242682 1.0955877826179055 1.1043881482292743 0.9046109592481628 0.9175776099071987 1.0 16.357178148210735 -5.287440124558336 1.7957744259399195 1.0264044640999712 0.9261583777617521 0.17112494602732253 0.0704883270507184 0.8069848906512668 4.57553989283603 0.022958686458695705 0.09609238134491895 5.158932854995164e-06 5.287440124558336 -0.10024608633821908 TLS(ph)PTPSAEGYQDVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLSPTPSAEGYQDVR 15 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4;H0Y7N6;F6XFR5 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 T(0.05)LS(0.949)PT(0.001)PSAEGYQDVR 209.56 3.4662e-13 6614300.0 13334.0 15047.0 18403.0 18177.0 18454.0 18616.0 16917.0 16377.0 16955.0 14031.0 True False 15591.182841495467 16540.76671784136 18841.79731376615 17158.601620629102 14838.071173147428 17639.74418840497 15314.499291526288 15947.121102865824 17202.934799291375 16574.709230665118 0.9406610170059567 0.997952150330278 1.1367799610569733 1.0352279115028888 0.8952236185051916 1.064256629960628 0.9239679006369961 0.9621357986396417 1.0379026600034689 1.0 14.016695940978895 TLS(ph)PTPSAEGYQDVR ddPTM_PC-9_Lapatinib_30min_R1 2 TLSPTPSAEGYQDVR 15 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4;H0Y7N6;F6XFR5 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 TLS(0.774)PT(0.226)PSAEGYQDVR;T(0.009)LS(0.876)PT(0.111)PS(0.004)AEGYQDVR 199.33 5.847799999999999e-10 112582500.0 36947.0 36584.0 35603.0 32446.0 32303.0 32530.0 30094.0 32017.0 35687.0 27173.0 True False 36420.12900475003 36499.29199571427 32675.85877155434 34832.18707668307 30403.001050141516 31138.76773113371 31652.120068927117 33504.62670380494 31667.55425923001 31869.81684425344 1.1427781082876562 1.1452620570141616 1.0252917025297006 1.0929522201808255 0.9539747654879789 0.9770613958438374 0.9931691864942244 1.051296493718202 0.9936534751356785 1.0 14.959903107524752 -5.379077220779724 1.1447027786619552 1.0000773299250194 1.1672720864178179 0.6909822546600883 0.0360404908919961 0.41719967999346574 0.8547420450434302 0.012301518263299095 0.06560320678638247 4.177560799132544e-06 5.379077220779724 0.16719475649279847 TLS(ph)PTPSAEGYQDVRDR ddPTM_PC-9_Lapatinib_30min_R1 1 TLSPTPSAEGYQDVRDR 17 1 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4;H0Y7N6;F6XFR5 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 T(0.066)LS(0.672)PT(0.206)PS(0.056)AEGYQDVRDR 55.536 0.024488 4381000.0 27489.0 2862.7 18538.0 10258.0 10245.0 10508.0 6677.9 7790.8 18283.0 8085.3 True False 27097.001819134788 2856.071594033764 17013.877198749386 11012.407539684853 9642.409242444977 10058.5973353444 7023.648986784348 8152.789009713706 16223.776011474822 9482.833332014947 2.857479496940301 0.3011833588165464 1.7941765507265555 1.161299281988424 1.0168278725189956 1.0607164528965851 0.7406698758557574 0.8597418856017552 1.7108574456013912 1.0 13.211102464389384 -4.745099004994212 24.997223697198972 1.0803078627475768 2.8574845771795294 0.6285548990866885 0.41178431937730475 617.0581263956637 943914.0529565484 0.09781470725149245 2.5950965888085213 1.7984608778998508e-05 4.745099004994212 1.7771767144319526 TLS(ph)QELVNLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLSQELVNLR 10 0 Q9ULD2-7;Q9ULD2-4;Q9ULD2-3;Q9ULD2-6;Q9ULD2-2;Q9ULD2;A0A0U1RQI2 Q9ULD2-7 MTUS1 Microtubule-associated tumor suppressor 1 1 T(0.012)LS(0.988)QELVNLR 80.312 0.017828 1164300.0 9888.6 10092.0 10808.0 8709.1 15794.0 9759.1 10502.0 10419.0 9891.5 6404.6 True False 11562.544671247351 11093.867064295533 11065.703709568259 8221.157362283157 12699.27907817766 9247.315616086322 9507.174532104338 10145.51228984302 10036.144474620498 7565.7032812143 1.5282841847574489 1.4663365257585097 1.4626140225515436 1.0866349176944798 1.6785325311012487 1.222267814685183 1.2566147757487036 1.3409873362380476 1.3265315994535924 1.0 12.88525848120337 -13.68993215151008 0.09177107717511765 6.978285505697304e-13 1.6765825169699675 0.40962932424116294 0.15012328060847732 176.78486745560238 1.3290091820369427 37.04645047147839 3.471800148659444 2.042056944020573e-14 13.68993215151008 1.6765825169692696 TLS(ph)SPSLQTDGIAATPVPPPPPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLSSPSLQTDGIAATPVPPPPPPK 24 0 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 T(0.234)LS(0.429)S(0.121)PS(0.183)LQT(0.033)DGIAATPVPPPPPPK 146.28 1.0869e-06 3106400.0 33214.0 31020.0 35769.0 41811.0 43721.0 34655.0 35634.0 33300.0 35246.0 27633.0 True False 38836.474193597634 34099.460595961915 36621.86861468788 39468.465223090956 35154.183903824574 32837.63079335914 32258.489552181094 32425.910284266472 35761.406071119054 32642.644157292358 1.1897465783243413 1.0446292411745115 1.1219026387145958 1.2091074801694246 1.0769404504864886 1.005973371370506 0.9882315108034702 0.9933604069577965 1.095542563855997 1.0 14.994470304447919 -6.553729182221774 4.654122957803637 1.015609791121664 1.1344554396787097 0.5786228824892428 0.049955077940879715 0.15147912353677456 7.915378534434626 0.016885960327017398 0.017338160908492786 2.794285761517657e-07 6.553729182221774 0.11884564855704571 TLS(ph)SPTEPVKR ddPTM_PC-9_Lapatinib_30min_R1 1 TLSSPTEPVKR 11 1 J3QQN1;P40306 J3QQN1 PSMB10 Proteasome subunit beta type-10 1 T(0.19)LS(0.684)S(0.117)PT(0.009)EPVKR 62.528 0.025072 9412500.0 60435.0 50913.0 50173.0 43536.0 62767.0 55867.0 51299.0 54615.0 53961.0 47730.0 True False 59573.18581757834 50795.11407658541 46047.96961338079 46737.78267183856 59075.16846466994 53477.6986423378 53955.011212065234 57152.61228185988 47883.34394547903 55980.06690377275 1.0641856845219926 0.9073785882374874 0.8225779667704793 0.8349004432627553 1.0552893508722943 0.9552989412153363 0.9638254149429922 1.0209457659295529 0.8553641786064381 1.0 15.77262559067756 -6.254547630013253 24.976816201683434 0.9746120539547931 0.9012203344115128 0.1512558680740418 0.07822287171107419 1030.8165361327783 3735843.7029055906 0.02378532179694911 0.03004153453325046 5.564836001538522e-07 6.254547630013253 -0.07339171954328028 TLS(ph)SSAQEDIIR ddPTM_PC-9_Lapatinib_30min_R1 2 TLSSSAQEDIIR 12 0 Q9H788-2;Q9H788 Q9H788-2 SH2D4A SH2 domain-containing protein 4A 1 T(0.001)LS(0.935)S(0.056)S(0.009)AQEDIIR;T(0.011)LS(0.986)S(0.003)SAQEDIIR 100.11 0.0031341999999999997 1729350.0 10763.5 10098.3 13860.0 10328.6 10775.7 12649.6 11006.599999999999 12899.7 12209.400000000001 9154.099999999999 True False 10610.01051621585 10074.918006787697 12720.484301147186 11088.19969919955 10141.894511841318 12108.606095657828 11576.46789229259 13499.067154670103 10834.248801318203 10736.373987928471 0.988230339977473 0.9383911195824133 1.18480264523661 1.032769509674929 0.9446293993898162 1.1278115040769106 1.0782474516357836 1.2573208766617006 1.009116188901372 1.0 13.390219211521753 -6.7918480412848385 24.984981495968103 1.1095660606616726 1.0234683983693798 0.13493786943268193 0.09276360259325792 375.41367952671243 308452.2447997579 0.0325123403001289 0.028676508280438072 1.6149235162839112e-07 6.7918480412848385 -0.08609766229229288 TLS(ph)SSSTDSQK ddPTM_PC-9_Lapatinib_30min_R1 1 TLSSSSTDSQK 11 0 A0A0A0MRY4;Q96N96-6 A0A0A0MRY4 SPATA13 Spermatogenesis-associated protein 13 1 T(0.09)LS(0.621)S(0.259)S(0.028)S(0.002)TDSQK 126.34 0.0014857000000000002 0.0 9376.7 8764.3 10441.0 6979.3 11968.0 9197.5 9002.8 12027.0 12852.0 10053.0 True False 9242.986538523815 8744.006801826985 9582.58128342553 7492.581004262285 11264.065769993313 8804.144365419688 9468.920932961288 12585.818326722125 11404.472422440225 11790.647655219505 0.7839252608343455 0.7416053008721851 0.8127273041853215 0.6354681458864099 0.9553390194818446 0.7467057470352151 0.8030874308053442 1.0674407967021737 0.9672473265191394 1.0 13.52535534666362 -7.714909496953968 7.241695003039419 1.0127521796410923 0.7810467940085818 0.6436868551049568 0.07805837146415678 0.12135048429003319 15.245940698735003 0.03600971451729565 0.020391040510509863 1.9279266338230297e-08 7.714909496953968 -0.23170538563251053 TLS(ph)TFRNYIMDFQVGK ddPTM_PC-9_AZD4547_30min_R2 1 TLSTFRNYIMDFQVGK 16 1 A0A0A0MQT0;P09455-2;P09455-3;A0A0A0MTB9;H0YAK8;P09455 A0A0A0MQT0 RBP1 Retinol-binding protein 1 1 T(0.15)LS(0.615)T(0.229)FRNY(0.005)IMDFQVGK 60.542 0.044706 0.0 12088.0 14062.0 13076.0 20167.0 16221.0 11910.0 14145.0 12781.0 18092.0 17752.0 True False 15931.732553980528 18607.266502602357 12902.603696293385 15517.809727044027 13968.994144841185 11165.265817231742 15403.87759750409 10805.990128162015 19048.306184449953 17130.507883288272 0.9300210281285815 1.0862063535637927 0.7531944635967603 0.9058581235751032 0.8154454170310202 0.6517766953146823 0.8992072916023347 0.6308038384958707 1.1119522149738827 1.0 14.064280304458777 -5.261911709412195 24.999966576748932 0.8288501958933959 1.0081136933537542 0.15954001104629012 0.14456733956610798 60.641786317064955 3209927.2374122133 0.0348849660606465 0.08048698025393687 5.471271806793468e-06 5.261911709412195 0.1792634974603583 TLS(ph)TSDDVEDRENEK ddPTM_PC-9_AZD4547_30min_R2 1 TLSTSDDVEDRENEK 15 1 Q96A65-2;Q96A65 Q96A65-2 EXOC4 Exocyst complex component 4 1 T(0.001)LS(0.917)T(0.063)S(0.018)DDVEDRENEK 118.2 0.0029169 0.0 5829.9 6831.9 8480.1 8514.8 8510.9 8780.4 8500.9 8144.8 9277.8 5741.0 True False 7683.686930546917 9040.178069913887 8367.64833320109 6551.84441234862 7329.3084438276865 8231.360199968221 9257.463631574583 6886.208308884595 9768.205566995906 5540.009337424402 1.3869447617427897 1.6317983453285558 1.510403290600099 1.1826414024411427 1.322977633686651 1.485802585992581 1.6710194997394099 1.2429957946760524 1.7632110294487753 1.0 12.435672692533036 -5.558123618929503 24.999924976390382 1.400837842851307 1.5248047214295588 0.06143358481607741 0.2193721616187267 518.8986472309231 368063.3071135412 0.057406396318756506 0.09943116522414905 2.7661541666327017e-06 5.558123618929503 0.12396687857825173 TLSAS(ph)TQDLSPH ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLSASTQDLSPH 12 0 Q6P597;Q6P597-3;Q6P597-2 Q6P597 KLC3 Kinesin light chain 3 1 T(0.002)LS(0.017)AS(0.858)T(0.121)QDLS(0.002)PH;TLS(0.002)AS(0.968)T(0.029)QDLSPH 186.16 0.00016141 45195000.0 147802.0 155966.0 238680.0 289770.0 334060.0 287220.0 255070.0 228390.0 231860.0 217043.0 True False 172821.95937743457 171449.27373661465 244371.03639894084 273535.1263470148 268603.34106977563 272157.6775780876 230907.9230531193 222395.00449920812 235250.51386397547 256391.17778855682 0.6740557957885707 0.6687019234258018 0.9531179602461639 1.066866374679227 1.0476309808572668 1.0614939247345447 0.900607911101944 0.8674050582294801 0.9175452755163993 1.0 17.9679870952871 -5.278256654829876 5.267876351525733 0.9793990566456326 0.6682352062832259 0.7796285656150468 0.06504427717290162 0.08202467304569255 7.481532671982035 0.01987041765534515 0.04645956956799857 5.269183766583267e-06 5.278256654829876 -0.3111638503624068 TLSASTQDLS(ph)PH ddPTM_PC-9_AZD4547_30min_R2 2 TLSASTQDLSPH 12 0 Q6P597;Q6P597-3;Q6P597-2 Q6P597 KLC3 Kinesin light chain 3 1 TLSASTQDLS(1)PH;TLSASTQDLS(1)PH 222.73 1.3418e-12 58705000.0 135014.0 138493.0 183410.0 304020.0 259080.0 225175.0 161721.0 226280.0 162796.0 209230.0 True False 177945.64353434218 183258.1538717756 180977.8635620347 233932.88606217704 223111.2140463256 211094.77165366584 176113.8557049105 191313.6253971135 171401.06420537896 201904.9213846551 0.8813338590956513 0.9076457998893698 0.8963519181251078 1.158628945039455 1.1050310835230694 1.0455157318899764 0.8722613322009656 0.9475431509301162 0.8489196946261536 1.0 17.623316550884823 -10.461175092484924 11.231548539738933 1.000000728417188 0.9683138972811075 0.009438674749914888 0.10060253277262793 0.0 0.0 0.10728746603523587 0.02602103263342028 3.457999351683886e-11 10.461175092484924 -0.031686831136080396 TLSASTQDLS(ph)PH ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLSASTQDLSPH 12 0 Q6P597;Q6P597-3;Q6P597-2 Q6P597 KLC3 Kinesin light chain 3 1 TLSASTQDLS(1)PH;TLSASTQDLS(1)PH 221.09 2.0915e-11 27027000.0 92572.0 96553.0 127084.0 125237.0 147964.0 143355.0 147038.0 131910.0 143847.0 118282.0 True False 108242.61121965792 106138.14374345311 130114.16452875409 118220.37691383203 118971.51636846142 135837.21143794555 133109.4961770669 128447.50227019783 145950.49024321247 139725.59028020286 0.7746799351685714 0.7596185031718659 0.9312121299171168 0.846089658141757 0.8514654769386077 0.9721713192661442 0.9526493744641323 0.9192840195744517 1.0445508940096537 1.0 17.09223674421313 -3.7629486628704516 0.2402962921509703 1.023291724776303 0.3708045898353288 0.7263628830847291 0.046971123398802155 9.268230979586223 0.30970358792369357 0.06905226237236069 1.9429786493606547 0.0001726041912082405 3.7629486628704516 -0.6524871349409741 TLSASTQDLS(ph)PH ddPTM_PC-9_Lapatinib_30min_R1 2 TLSASTQDLSPH 12 0 Q6P597;Q6P597-3;Q6P597-2 Q6P597 KLC3 Kinesin light chain 3 1 TLSASTQDLS(1)PH;TLSASTQDLS(1)PH 210.93 2.1830000000000004e-08 62675000.0 180888.0 156274.0 233049.0 156471.0 270790.0 218063.0 204554.0 213859.0 266680.0 190359.0 True False 178308.5039492038 155912.1571544461 213888.61081515567 167978.39931195445 254862.66459362357 208736.95381968055 215144.80522959106 223795.6698706629 236643.69013510417 223262.29951257588 0.7986503065608713 0.6983362506559864 0.9580149057055994 0.752381390313919 1.1415391902261927 0.9349404457241239 0.9636414464031462 1.0023889853291463 1.0599357377028833 1.0 17.768380129993922 -5.850155747001518 1.2230255001321213 1.0082282186454685 0.7601804670970885 0.5172164482426651 0.09222436885765742 0.3859667837293508 1.1568369958836606 0.03190720014441952 0.0738478041981881 1.412031070207399e-06 5.850155747001518 -0.24804775154838 TLSDVEDQKELAS(ph)PVSPELR ddPTM_PC-9_AZD4547_30min_R2 1 TLSDVEDQKELASPVSPELR 20 1 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 TLS(0.001)DVEDQKELAS(0.88)PVS(0.119)PELR 50.722 0.022484 7271200.0 14039.0 15476.0 18970.0 22849.0 20648.0 21385.0 19989.0 21707.0 15932.0 19891.0 True False 18503.109970659563 20478.31435032528 18718.44540522219 17581.516063530977 17781.381610423574 20047.792569395522 21767.982276175975 18352.68192723676 16774.132994177355 19194.622144349196 0.9639736500937993 1.0668777012812412 0.9751921795831137 0.9159605191137816 0.926373099543318 1.0444484094883575 1.1340667251730383 0.9561366610511634 0.8738975358843195 1.0 14.228414539846886 -7.98988872508513 24.999719683736608 0.9296381618726544 1.0035618579241319 0.14329825296494914 0.06839159010800187 366.2076553217723 905433.697233273 0.03999426930760061 0.019180444140616516 1.0235552139622925e-08 7.98988872508513 0.07392369605147753 TLSDVEDQKELAS(ph)PVSPELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TLSDVEDQKELASPVSPELR 20 1 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 TLS(0.001)DVEDQKELAS(0.966)PVS(0.033)PELR;T(0.002)LS(0.003)DVEDQKELAS(0.735)PVS(0.261)PELR;TLSDVEDQKELAS(0.5)PVS(0.5)PELR 49.395 0.026623 30123300.0 102943.0 104708.0 92061.0 122086.0 115475.0 106236.0 113469.0 113728.0 111309.0 97981.0 True False 120369.21668307087 115102.7182489356 94256.08338328688 115245.91722815228 92848.50269422338 100664.79714221053 102720.39487558056 110742.76050477677 112936.68354906038 115744.179682831 1.0399591323979631 0.9944579378794409 0.8143483641386801 0.995695140299546 0.8021872283224288 0.8697180058475348 0.8874778425754195 0.956789022206046 0.9757439541110068 1.0 16.82058012231682 -10.535712387244978 9.123055427881448 0.9999999995790854 0.9214648066028225 0.07403652382327419 0.0765552016527633 1.6037214484209404e-10 0.0 0.07559298027215172 0.018333990582066632 2.9126453871814634e-11 10.535712387244978 -0.07853519297626288 TLSDVEDQKELAS(ph)PVSPELR ddPTM_PC-9_Lapatinib_30min_R1 2 TLSDVEDQKELASPVSPELR 20 1 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 TLSDVEDQKELAS(0.868)PVS(0.132)PELR;TLSDVEDQKELAS(0.726)PVS(0.274)PELR 53.519 0.013756 15196800.0 57445.0 51817.0 46993.0 43574.0 54870.0 46791.0 43931.0 41472.0 53779.0 36258.0 True False 56625.82376587718 51697.02092012697 43129.416938225826 46778.57731860286 51642.65447857059 44789.85800514843 46205.53222396611 43398.94052097944 47721.84270202401 42525.14698925186 1.3315844335632572 1.2156811811419084 1.0142097086490187 1.1000215315052537 1.214402727205697 1.0532558068868987 1.0865460908493618 1.0205476898633281 1.1222028865434752 1.0 15.37602860215882 -5.009326524999015 3.6187098613169106 1.0827948368701814 1.321270632198153 0.6520041766125462 0.06019481833222581 0.13816834777824805 3.8219710811673324 0.015665509257321315 0.06568141629782853 9.787538310747492e-06 5.009326524999015 0.2384757953279717 TLSDVEDQKELASPVS(ph)PELR ddPTM_PC-9_AZD4547_30min_R2 2 TLSDVEDQKELASPVSPELR 20 1 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 TLSDVEDQKELAS(0.008)PVS(0.992)PELR;T(0.001)LS(0.001)DVEDQKELAS(0.083)PVS(0.914)PELR 63.443000000000005 0.00387 28329800.0 104454.0 83665.0 110856.0 135596.0 118439.0 120132.0 91490.0 118123.0 101061.0 110706.0 True False 137668.19922182994 110708.07509175279 109385.97700797634 104336.43713731665 101995.78925595482 112620.12704917596 99632.4327603851 99869.80454650508 106402.87813987928 106830.21663628367 1.2886634845133553 1.0362992660463448 1.0239235719271642 0.976656609174 0.9547466294411042 1.0541973104164408 0.9326240823754547 0.9348460359911451 0.9959998349731021 1.0 16.70496024155218 TLSDVEDQKELASPVS(ph)PELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLSDVEDQKELASPVSPELR 20 1 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 TLSDVEDQKELAS(0.022)PVS(0.978)PELR;TLSDVEDQKELAS(0.064)PVS(0.936)PELR 60.618 0.0062657 23569900.0 88294.0 89201.0 92470.0 111896.0 113921.0 99528.0 107891.0 102636.0 101171.0 76769.0 True False 103240.4303140094 98056.28577112818 94674.83549442774 105626.82989172681 91598.99783874133 94308.57647096956 97670.7834168032 99941.91375183123 102650.43447827228 90686.6119969304 1.1384307787074892 1.081265289461329 1.0439780846331796 1.1647455734182914 1.010060865895418 1.0399393515126771 1.077014360400951 1.1020580827875024 1.131924902892467 1.0 16.468601961931896 -9.104399216575674 0.006952137826375488 2.311081969639144e-05 2.121112671003423 0.15035123944010576 0.04875072988483632 12912.001990094379 35.5987513136383 5530.427114096559 5328.346254967964 7.863226459054837e-10 9.104399216575674 2.121089560183727 TLSDVEDQKELASPVS(ph)PELR ddPTM_PC-9_Lapatinib_30min_R1 1 TLSDVEDQKELASPVSPELR 20 1 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 TLSDVEDQKELAS(0.093)PVS(0.907)PELR 56.818999999999996 0.009487200000000001 15334000.0 45700.0 42758.0 40682.0 30986.0 33596.0 44408.0 32828.0 32355.0 47577.0 26396.0 True False 45048.30961964638 42658.99647804369 37337.28299706131 33264.81380626583 31619.949332277345 42508.773360104125 34527.67321136238 33858.33141773463 42218.37725197934 30958.513429540842 1.4551186290702496 1.3779407262280934 1.2060425020742047 1.074496483236314 1.0213652346144424 1.373088325343876 1.1152884743624614 1.0936678692532686 1.3637081556924582 1.0 14.918048577151927 -5.231613229753047 2.7928898495993226 1.1544313691431096 1.4416185784399411 0.4375634415807387 0.12070298885596406 0.2587322037277764 3.9300972818548345 0.03208533011024003 0.10456242859979699 5.866603949099648e-06 5.231613229753047 0.2871872092968315 TLSDYNIQK ddPTM_PC-9_Lapatinib_30min_R1 2 TLSDYNIQK 9 0 P62987;P0CG48;M0R2S1;Q96C32;Q5PY61;J3QKN0;F5GXK7;F5H747;F5H388;B4DV12;F5H265;F5H2Z3;F5GYU3;F5H6Q2;J3QTR3;J3QS39;P0CG47;M0R1M6;Q49A90;M0R1V7;P62979;A0A2R8Y422 P62987;P62979 UBA52;UBC;UBB;RPS27A Ubiquitin-60S ribosomal protein L40;Ubiquitin;60S ribosomal protein L40;Polyubiquitin-C;Ubiquitin;Polyubiquitin-B;Ubiquitin;Ubiquitin-40S ribosomal protein S27a;Ubiquitin;40S ribosomal protein S27a 0 ; 118.18 0.0083556 18343300.0 72255.0 74095.0 75513.0 79334.0 71164.0 62354.0 74933.0 65254.0 74057.0 83218.0 False True 71224.63045005586 73923.43757988315 69304.61262860951 85168.48701046602 66978.27343380706 59687.2647742734 78812.66409001502 68285.93906143897 65715.92080521747 97602.12041898505 0.7297447037452028 0.7573958154038624 0.7100728173844955 0.872608982723489 0.686237892642943 0.6115365579973951 0.807489261008768 0.6996358149628514 0.6733042327678236 1.0 16.574624870418802 -10.54933458155231 5.8732581742015455 1.0000005187391627 0.7290898640598117 0.5841418318723997 0.06895081980087052 4.720946411643206e-07 7.837562435668762e-08 0.06730176885484483 0.016323045442302585 2.822704518431839e-11 10.54933458155231 -0.27091065467935105 TLSGGRPGAGPELELGTAGS(ph)PGGAPPEAAPGDCTR ddPTM_PC-9_AZD4547_30min_R2 2 TLSGGRPGAGPELELGTAGSPGGAPPEAAPGDCTR 35 1 Q8WYP3;Q8WYP3-2 Q8WYP3 RIN2 Ras and Rab interactor 2 1 TLS(0.001)GGRPGAGPELELGT(0.23)AGS(0.768)PGGAPPEAAPGDCTR;TLSGGRPGAGPELELGT(0.369)AGS(0.63)PGGAPPEAAPGDCTR 73.08800000000001 1.0688e-06 11009500.0 5943.1 7972.9 8387.8 13450.2 10941.3 11128.5 6035.6 11967.7 6279.700000000001 10566.3 True False 7832.882175840648 10549.984006442777 8276.572291508839 10349.464193518506 9422.28935558541 10432.63313577358 6572.7567074935105 10118.366955387268 6611.632121738362 10196.377053131411 0.7682024835904916 1.034679666264673 0.8117169704867887 1.015013875966864 0.9240820839095715 1.0231705910257225 0.6446168745275019 0.9923492337192272 0.6484295438748867 1.0 13.31576900861311 -7.22647650596006 24.9994285536934 0.8207111113962461 0.932549511299498 0.12879152325228815 0.13762978635474118 1175.1333401596737 840254.1827167976 0.04804703790184698 0.037215479228307737 5.936404615063084e-08 7.22647650596006 0.11183839990325195 TLSGGRPGAGPELELGTAGS(ph)PGGAPPEAAPGDCTR ddPTM_PC-9_Lapatinib_30min_R1 1 TLSGGRPGAGPELELGTAGSPGGAPPEAAPGDCTR 35 1 Q8WYP3;Q8WYP3-2 Q8WYP3 RIN2 Ras and Rab interactor 2 1 T(0.002)LS(0.001)GGRPGAGPELELGT(0.028)AGS(0.97)PGGAPPEAAPGDCTR 51.788999999999994 0.0016495999999999998 3853500.0 5398.4 3916.0 4412.4 4712.6 6273.8 6078.0 4760.8 4373.8 5978.7 2301.2 True False 5321.417826054685 3906.932742598323 4049.629504356554 5059.180324772752 5904.787418765377 5818.058108510018 5007.290929226697 4577.022715341916 5305.315847497922 2698.9593538437425 1.9716554154386021 1.447570055856616 1.5004410861502027 1.8744929661751608 2.1878015355644505 2.15566718343653 1.8552672614708061 1.6958472193453067 1.9656894202361062 1.0 11.39818753473487 -10.611618184176635 4.4759582111606875 0.9999346982268471 1.8435406980488698 0.544290604991682 0.2333861971915059 92926249.12104468 9.69039946728594 67387.47360873426 0.06329690003930821 2.4455796720380408e-11 10.611618184176635 0.8436059998220227 TLSNAEDYLDDEDS(ph)D ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLSNAEDYLDDEDSD 15 0 Q92882 Q92882 OSTF1 Osteoclast-stimulating factor 1 1 TLSNAEDYLDDEDS(1)D 106.01 0.0043808 0.0 1143.1 949.58 1998.2 1022.6 831.53 0.0 0.0 0.0 526.08 454.74 True False 1336.6042527458737 1043.8480268444066 2045.8446662156998 965.307037313931 668.5976656880504 0.0 0.0 0.0 533.7729247544207 537.1807622801408 2.4881833948640777 1.9431969648608485 3.8084846105281556 1.7969873552741293 1.244641864779542 0.0 0.0 0.0 0.9936560693066241 1.0 9.069263829126818 -6.307197878854264 2.1903685988690325 0.3302296604018827 2.6561084439192237 0.7397142812693074 0.5952824112157261 0.1520100995039576 1.4318205810269713 0.20103650820654093 0.25032951352829597 4.929491489284094e-07 6.307197878854264 2.325878783517341 TLSPT(ph)PSAEGYQDVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLSPTPSAEGYQDVR 15 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4;H0Y7N6;F6XFR5 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 T(0.006)LS(0.423)PT(0.568)PS(0.002)AEGYQDVR 97.76700000000001 0.005835100000000001 18702000.0 8808.6 5212.0 10787.0 6864.5 8243.8 7467.8 9760.3 8246.5 9852.0 6086.3 True False 10299.722002219669 5729.412915091987 11044.202989925312 6479.904320009273 6628.48656861346 7076.175421689442 8835.733725547325 8030.038112888993 9996.06686184716 7189.69801087571 1.4325667067851096 0.7968920122132002 1.5361150041655396 0.9012762859034209 0.9219422788810717 0.9842103814354172 1.228943651344144 1.1168811403124468 1.390331950900624 1.0 12.811715459031557 -10.573910689929356 14.904009858898773 0.9996228625984424 1.129815852649355 0.029088475134928404 0.23708236546789102 0.0 0.0 0.21845662225824997 0.05298351342273076 2.6674071444980968e-11 10.573910689929356 0.13019299005091256 TLSPTPS(ph)AEGYQDVR ddPTM_PC-9_Lapatinib_30min_R1 1 TLSPTPSAEGYQDVR 15 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;J3QSX6;A0A494C1P1;A0A494C1G0;O14639-4;H0Y7N6;F6XFR5 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 TLS(0.014)PT(0.306)PS(0.68)AEGYQDVR 123.68 3.1382e-05 5925300.0 11166.0 12580.0 14964.0 10936.0 13296.0 10020.0 7906.1 12077.0 14702.0 9039.9 True False 11006.77079240638 12550.871782912898 13733.71768271043 11740.269921426563 12513.955420941767 9591.46795776084 8315.4391731556 12638.141509256106 13046.105941076576 10602.4346700904 1.0381361578634969 1.1837726119944 1.2953362232406316 1.107318298743779 1.1802907360744028 0.9046476829344198 0.7842952521663309 1.1920037144778133 1.2304820870889024 1.0 13.372107972936334 -6.732101973631701 24.93326630005128 1.0194115354263584 1.1667217025350702 0.20987451550205372 0.1342555918386376 345.12710556527134 293315.58793899795 0.048070586462364694 0.048063349358700276 1.8530964597861893e-07 6.732101973631701 0.1473101671087118 TLSQGESQTS(ph)EHELFLDTK ddPTM_PC-9_AZD4547_30min_R2 1 TLSQGESQTSEHELFLDTK 19 0 Q5VZL5-2;Q5VZL5-4;Q5VZL5;H7C1I7;Q5VZL5-3 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 T(0.01)LS(0.066)QGES(0.038)QT(0.048)S(0.838)EHELFLDTK 71.65100000000001 0.0064432000000000005 4648500.0 32634.0 31797.0 53213.0 58279.0 49469.0 57658.0 45238.0 58494.0 45915.0 53484.0 True False 43010.93317063211 42074.758425774926 52507.36085124345 44843.67695157431 42601.083247096285 54052.6361452517 49264.09436238175 49455.096358399904 48341.97316266968 51611.541439262604 0.8333588180319736 0.8152199537634284 1.017356959063799 0.8688691657145555 0.8254177662418785 1.047297457853721 0.9545170128343605 0.9582177741503721 0.9366504431873903 1.0 15.655406098595575 -6.753997768636089 24.999417364880415 0.9751739306123928 0.8767841184357708 0.4414971768467004 0.060128377337036285 188.1910873554063 632210.2373785129 0.02082062442465925 0.02042896694773985 1.761985099300915e-07 6.753997768636089 -0.09838981217662202 TLSQGESQTS(ph)EHELFLDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLSQGESQTSEHELFLDTK 19 0 Q5VZL5-2;Q5VZL5-4;Q5VZL5;H7C1I7;Q5VZL5-3 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 T(0.052)LS(0.213)QGES(0.038)QT(0.074)S(0.624)EHELFLDTK 81.48 0.0074298 0.0 11358.0 15099.0 16617.0 18776.0 17592.0 18461.0 18560.0 18746.0 12107.0 13713.0 True False 13280.685069274456 16597.928934185333 17013.21230032343 17724.041592613325 14144.973885228663 17492.872661266876 16801.86243723638 18253.937363028814 12284.041970806291 16199.058347951732 0.8198430293915026 1.024623072382725 1.0502593382210172 1.0941402402476326 0.8731972921757644 1.0798697236298762 1.0372122919947917 1.1268517571169134 0.7583182742445971 1.0 13.98362233116399 -4.759193472048511 24.70613914568636 1.012342092037621 0.8198427383224647 0.2152631314077612 0.10517231396188179 75.75103627134682 833075.1445848661 0.024764274982694238 0.15980565206433434 1.7410310958794864e-05 4.759193472048511 -0.19249935371515625 TLSS(ph)PSNRPSGETSVPPPPAVGR ddPTM_PC-9_AZD4547_30min_R2 1 TLSSPSNRPSGETSVPPPPAVGR 23 1 Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 T(0.099)LS(0.233)S(0.571)PS(0.088)NRPS(0.004)GET(0.002)S(0.002)VPPPPAVGR 41.294 0.046102 68594000.0 43937.0 57439.0 50189.0 103510.0 57181.0 65494.0 56881.0 76738.0 50933.0 69531.0 True False 57908.052053626954 76005.03346913507 49523.46106708998 79647.36871355829 49242.405165906166 61398.64982651344 61943.29880690205 64879.905363813305 53625.21439821968 67096.74085358912 0.8630531277217671 1.132767888607058 0.7380904115023179 1.1870527197044596 0.7339015955090479 0.9150764857639002 0.9231938544089299 0.9669606084949322 0.7992223424865678 1.0 16.03395507043752 -6.290072064320814 24.999434522745478 0.8910148201873773 0.9738395051324461 0.09261686854349827 0.13818097350270414 1920.679171033807 1676955.4650464528 0.03996960204688135 0.04533021889099072 5.127762897922988e-07 6.290072064320814 0.08282468494506878 TLSS(ph)PSNRPSGETSVPPPPAVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLSSPSNRPSGETSVPPPPAVGR 23 1 Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 T(0.302)LS(0.302)S(0.344)PS(0.032)NRPS(0.017)GET(0.002)S(0.002)VPPPPAVGR 45.489 0.027107999999999997 22685000.0 20380.0 17862.0 18753.0 17831.0 26755.0 17156.0 19220.0 19594.0 21247.0 19396.0 True False 23829.931476651986 19635.221314154467 19200.142641148537 16831.98687888198 21512.549812374527 16256.309158588072 17399.342459250183 19079.67826155908 21557.6971796251 22912.341261348476 1.0400478591356974 0.8569714063781739 0.8379825711455268 0.7346253570025325 0.9389066602575749 0.7095001324029393 0.7593873651228153 0.8327249513232926 0.9408770991025449 1.0 14.483837265235127 -8.40640831983952 3.1563551716034697 0.9973970598284299 0.8321034936299111 0.25364340692587106 0.09234406115901306 0.3231364561788141 5.96877430229869 0.08934541874376342 0.023954170167950737 3.922759475828987e-09 8.40640831983952 -0.16529356619851876 TLSS(ph)SSMDLSR ddPTM_PC-9_AZD4547_30min_R2 3 TLSSSSMDLSR 11 0 Q9H0B6;Q9H0B6-2 Q9H0B6 KLC2 Kinesin light chain 2 1 T(0.001)LS(0.121)S(0.348)S(0.348)S(0.182)MDLSR;TLS(0.001)S(0.968)S(0.03)S(0.001)MDLSR;TLS(0.001)S(0.966)S(0.031)S(0.001)MDLSR 228.93 1.694e-13 138570000.0 359410.0 365830.0 568730.0 759250.0 578450.0 467750.0 432250.0 566540.0 450000.0 492460.0 True False 473694.90380758885 484077.393304439 561188.268598419 584216.6427955667 498142.2022738057 438501.51855668775 470719.41262079455 478994.26079406124 473786.0813067922 475219.12529315817 0.996792592291758 1.01864038617094 1.1809042160334504 1.2293626491466836 1.0482368569794123 0.9227354187106428 0.9905312887616049 1.0079439889936548 0.9969844564115934 1.0 18.85823337330774 -6.523481715061304 24.953765389052492 0.984668483514258 1.1096402276698074 0.42586779308626976 0.06725038211630531 21.624348702781298 894853.889792647 0.02436096265934258 0.02458182168243739 2.995837722411759e-07 6.523481715061304 0.12497174415554946 TLSS(ph)SSMDLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLSSSSMDLSR 11 0 Q9H0B6;Q9H0B6-2 Q9H0B6 KLC2 Kinesin light chain 2 1 TLS(0.018)S(0.327)S(0.327)S(0.327)MDLSR 86.463 0.0096024 48139000.0 56538.0 52824.0 68372.0 68529.0 73244.0 70905.0 74119.0 68278.0 58042.0 48937.0 True False 66108.76672359907 58068.01761834599 70002.2477822541 64689.54230401567 58892.363986453354 67186.61697888127 67097.91174490978 66485.77484652083 58890.75444532411 57808.890714921145 1.1435743863276662 1.004482474931109 1.2109252904966348 1.1190241069150726 1.0187423293914297 1.1622194466627194 1.160684990061417 1.1500960150643416 1.0187144869417764 1.0 15.819003768537407 -8.335528864993858 5.798825678732033 1.0044591968805117 1.119416284826873 0.35186441437093763 0.06075417328696354 0.272778260669892 15.87838431948907 0.05792031121197012 0.015173646652519681 4.618182965356386e-09 8.335528864993858 0.11495708794636128 TLSS(ph)SSMDLSR ddPTM_PC-9_Lapatinib_30min_R1 3 TLSSSSMDLSR 11 0 Q9H0B6;Q9H0B6-2 Q9H0B6 KLC2 Kinesin light chain 2 1 TLS(0.182)S(0.375)S(0.067)S(0.375)MDLSR;TLS(0.002)S(0.801)S(0.188)S(0.008)MDLSR;TLS(0.001)S(0.985)S(0.013)S(0.001)MDLSR 223.77 3.979e-13 145317000.0 444610.0 343924.0 421937.0 351692.0 369758.0 396899.0 354617.0 319072.0 381241.0 294932.0 True False 438269.77986851154 343127.66510862834 387246.9685839198 377556.60289011896 348009.56141219795 379924.5549867586 372977.3331056929 333897.24994960276 338301.62393429305 345910.6032278122 1.2670030226852362 0.9919547475757745 1.1195001395458353 1.0914860642229725 1.0060679209159813 1.098331625112241 1.0782477600435245 0.9652703526110253 0.9780030469649755 1.0 18.400039711882044 -4.753565118439014 24.98129025455157 1.0420465241780879 1.2670034337123361 0.6252282036155498 0.053375642488597816 203.1854453370529 644559.079916678 0.013862963831553098 0.14731563230405895 1.7637412879628572e-05 4.753565118439014 0.2249569095342483 TLSSFFT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 TLSSFFTPR 9 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;F5GZ28 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 TLSSFFT(0.999)PR;TLSSFFT(1)PR 126.03 0.0034419000000000003 73011000.0 79430.0 65639.0 79465.0 140885.0 124850.0 120437.0 83290.0 112461.0 100408.0 116653.0 True False 104687.08775336487 86855.52310939519 78411.24217849132 108406.13990155206 107516.73256787012 112906.05535096019 90702.64864588997 95082.73654668895 105715.36189300517 112569.01397640955 0.929981387020975 0.7715757653131528 0.6965615084353809 0.9630193609430577 0.9551183649028123 1.0029940865842644 0.8057514714031164 0.8446617162926815 0.9391159978993806 1.0 16.78045023671652 -5.779283908537109 24.999999481076575 0.9225212019030148 0.7965931335559924 0.35804364923381893 0.07973634278689806 276.15074291708066 386883.4062380223 0.023575375456937133 0.03505042646956592 1.662325593677771e-06 5.779283908537109 -0.12592806834702241 TLSSFFT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TLSSFFTPR 9 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;F5GZ28 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 TLSSFFT(1)PR;TLS(0.001)S(0.001)FFT(0.998)PR;TLSS(0.001)FFT(0.999)PR;TLSSFFT(1)PR 144.55 0.0013265999999999998 68814000.0 124147.0 114134.0 134903.0 127749.0 149825.0 135250.0 135214.0 116459.0 95622.0 100108.0 True False 145162.635084981 125464.4692346719 138119.5991424764 120591.63769784632 120467.86677776181 128157.25190598262 122405.5510554141 113402.07464851027 97020.29085094886 118256.78794550811 1.2275205305920445 1.0609494086080287 1.1679633917176993 1.0197438962524004 1.0186972677904338 1.0837200479775975 1.0350826635999761 0.9589476986366748 0.8204204810268915 1.0 16.851563471145326 -5.944263315963974 0.3894448062781217 0.9257367371344644 1.2325934155361713 0.5684957902644545 0.06925656160908898 1.9283139214909437 0.4403215372626416 0.06869763408509157 0.2554136971305764 1.1369377430249346e-06 5.944263315963974 0.30685667840170694 TLSSFFT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 TLSSFFTPR 9 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;F5GZ28 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 TLSSFFT(1)PR;TLSSFFT(1)PR 123.11 0.0037059 45869000.0 107822.0 86158.0 111056.0 84018.0 97858.0 82749.0 69342.0 68267.0 98961.0 59500.0 True False 106284.43850786677 85958.50644453175 101925.40436855712 90196.96399583179 92102.18483623047 79210.01816734043 72932.1894669882 71438.93404093609 87814.97007447148 69784.4957212336 1.5230379958958016 1.2317708332794732 1.4605737752367807 1.2925072118617775 1.3198087037004436 1.1350661396731838 1.045105918058484 1.0237078208075248 1.2583736425532652 1.0 16.090618922708025 -6.728042009417807 2.1165217903117886 1.0812076962391453 1.3724473950547598 0.6580026462207945 0.0996679146643288 0.19345261277545944 1.7817941993743722 0.03708380001040213 0.03489816756253696 1.8705011975489303e-07 6.728042009417807 0.2912396988156145 TLSSPSNRPS(ph)GETSVPPPPAAPPFLPVGR ddPTM_PC-9_Lapatinib_30min_R1 1 TLSSPSNRPSGETSVPPPPAAPPFLPVGR 29 1 H3BUF6 H3BUF6 ATXN2L 1 T(0.021)LS(0.061)S(0.061)PS(0.061)NRPS(0.265)GET(0.265)S(0.265)VPPPPAAPPFLPVGR 68.303 6.7785e-05 6534700.0 4149.7 4282.2 2069.0 3999.7 3705.1 3871.1 1779.4 1914.8 2148.0 1508.1 True False 4090.5245170382195 4272.284828997582 1898.8948065709606 4293.8512806080635 3487.1733025068665 3705.542076974845 1871.5286253289325 2003.76859832107 1906.069620557235 1768.7730755830644 2.312633866664781 2.4153945398503147 1.0735660966260483 2.4275874276255722 1.97152102247901 2.094978789607218 1.0580942525439536 1.1328579261986678 1.0776224756411514 1.0 10.788533254267154 -7.262917148766429 24.347207428382443 1.0782150850590477 2.0352324960664694 0.6371621576745435 0.3629541058688761 62.75933329642355 1033981.9266353548 0.14639982153964115 0.10476642128404064 5.4586198635010476e-08 7.262917148766429 0.9570174110074217 TLSSPSNRPS(ph)GETSVPPPPAVGR ddPTM_PC-9_Lapatinib_30min_R1 1 TLSSPSNRPSGETSVPPPPAVGR 23 1 Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 T(0.201)LS(0.225)S(0.074)PS(0.183)NRPS(0.273)GET(0.018)S(0.024)VPPPPAVGR 47.472 0.022049000000000003 10443000.0 9795.1 11038.0 6726.6 2477.5 9327.5 9381.7 7085.5 5492.2 7506.6 6376.2 True False 9655.420077798652 11012.4421891727 6173.564913426891 2659.703614697724 8778.874788570567 8980.466560810864 7452.352520382233 5747.387662261845 6661.1276599976445 7478.317674247551 1.2911219472593687 1.47258282796615 0.8255285723801589 0.35565533995121923 1.1739103861289064 1.2008672206766686 0.996527941845165 0.7685401867927646 0.8907254211647101 1.0 12.868498041940962 -5.2627839202028515 24.9971164869389 0.8975273595957064 1.3818524133145982 0.4148329853982021 0.22818009234928763 114.76437343951837 2133698.5666939165 0.06389085837705206 0.14589657316241406 5.46029466176264e-06 5.2627839202028515 0.4843250537188918 TLSSPSNRPSGET(ph)SVPPPPAAPPFLPVGR ddPTM_PC-9_AZD4547_30min_R2 1 TLSSPSNRPSGETSVPPPPAAPPFLPVGR 29 1 H3BUF6 H3BUF6 ATXN2L 1 T(0.129)LS(0.129)S(0.148)PS(0.048)NRPS(0.021)GET(0.263)S(0.263)VPPPPAAPPFLPVGR 70.78399999999999 6.0506000000000007e-05 6106600.0 0.0 1622.9 1400.4 2170.3 2553.6 2798.5 1632.2 1523.4 0.0 0.0 True False 0.0 2147.4706874607705 1381.8297809948942 1669.9708658007469 2199.07671834452 2623.5093526047876 1777.4626380096272 1287.993534249435 0.0 0.0 0.0 TLSSPSNRPSGET(ph)SVPPPPAAPPFLPVGR ddPTM_PC-9_Lapatinib_30min_R1 1 TLSSPSNRPSGETSVPPPPAAPPFLPVGR 29 1 H3BUF6 H3BUF6 ATXN2L 1 T(0.006)LS(0.007)S(0.021)PS(0.07)NRPS(0.096)GET(0.4)S(0.4)VPPPPAAPPFLPVGR 64.547 0.00016871 5228100.0 921.79 1435.1 2210.1 1298.7 1166.6 1552.0 1015.3 1716.8 1283.4 1969.8 True False 908.6451055644172 1431.7771141222815 2028.3941092327118 1394.2107303361988 1097.982881623846 1485.6245778887035 1067.867266098946 1796.5687954865348 1138.8499771988618 2310.2773054064837 0.39330564492756637 0.6197425351370823 0.877987289441786 0.603481983341776 0.47526021186043743 0.6430503275135251 0.46222471371723883 0.7776420567705122 0.49294947170789344 1.0 11.173850315144767 -11.200922202711148 2.8781279183270914 1.0469621406044578 0.6028329944000549 0.4245102166036525 0.14148974849665766 50937344.39956916 48762553.45872624 17569762.564126372 0.035392461602702714 6.296189594710146e-12 11.200922202711148 -0.4441291462044029 TLSSSS(ph)MDLSR ddPTM_PC-9_AZD4547_30min_R2 3 TLSSSSMDLSR 11 0 Q9H0B6;Q9H0B6-2 Q9H0B6 KLC2 Kinesin light chain 2 1 TLS(0.003)S(0.099)S(0.148)S(0.75)MDLSR;TLS(0.004)S(0.019)S(0.086)S(0.89)MDLSR;TLS(0.023)S(0.146)S(0.146)S(0.685)MDLSR 124.12 0.00046435 164878000.0 278386.0 266414.0 398718.0 559744.0 436633.0 364521.0 355772.0 421219.0 340297.0 390277.0 True False 366906.95721148467 352527.1154902793 393430.7388022867 430703.6687585925 376014.0447841954 341727.4442454343 387435.0187783112 356129.28219969367 358284.4046899053 376613.521021074 0.9742267250966644 0.9360447668859799 1.0446537812440135 1.14362242648875 0.9984082455795711 0.9073690273226076 1.028733694233542 0.9456093908528737 0.9513317623820972 1.0 18.522725270352538 -6.525842872551325 24.9682562790076 0.9655139947745912 1.0261482695066535 0.18019981114865402 0.05841344079128848 165.02477073180404 1390059.5554662817 0.020658958615075097 0.020760422447760198 2.9795942496165485e-07 6.525842872551325 0.06063427473206229 TLSSSS(ph)MDLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TLSSSSMDLSR 11 0 Q9H0B6;Q9H0B6-2 Q9H0B6 KLC2 Kinesin light chain 2 1 T(0.011)LS(0.224)S(0.224)S(0.12)S(0.421)MDLSR;TLS(0.007)S(0.044)S(0.182)S(0.767)MDLSR;TLS(0.006)S(0.032)S(0.187)S(0.775)MDLSR 101.71 0.0031879 124737000.0 257541.0 247664.0 271508.0 281428.0 345125.0 281946.0 301315.0 301171.0 267200.0 227607.0 True False 301137.604633387 272250.4451656455 277981.7804198239 265660.5015618861 277500.23375054175 267160.2554224339 272772.26186831295 293265.5803670518 271107.2945072633 268870.34736397915 1.1200104719087023 1.0125714785390245 1.0338878316079618 0.9880617337182677 1.0320968320648614 0.9936397153560774 1.0145122529969868 1.0907323296981053 1.0083197986137753 1.0 18.03655112935064 -4.758445705766514 24.99964777664377 1.0210748900542068 1.1200106061701407 0.5415274505048877 0.027753543875591445 67.1659568470233 560792.8539791474 0.006932040766689392 0.04756906694800121 1.744031377569768e-05 4.758445705766514 0.09893571611593388 TLSSSS(ph)MDLSR ddPTM_PC-9_Lapatinib_30min_R1 6 TLSSSSMDLSR 11 0 Q9H0B6;Q9H0B6-2 Q9H0B6 KLC2 Kinesin light chain 2 1 TLS(0.008)S(0.152)S(0.152)S(0.687)MDLSR;TLS(0.022)S(0.162)S(0.162)S(0.654)MDLSR;TLS(0.003)S(0.043)S(0.219)S(0.736)MDLSR;TLS(0.004)S(0.085)S(0.131)S(0.78)MDLSR;TLS(0.043)S(0.229)S(0.156)S(0.571)MDLSR;TLS(0.002)S(0.01)S(0.207)S(0.782)MDLSR 116.74 0.0010843 199288000.0 1013187.0 873985.0 1001332.0 766933.0 871017.0 873194.0 836128.0 769834.0 882353.0 624289.0 True False 998738.7675842594 871961.3414299764 919006.3482132993 823335.8112334869 819785.4925453091 835849.5281346315 879418.6166342765 805603.2980571877 782973.1135509956 732196.5218371972 1.3640310187192168 1.190884298715442 1.2551361838039965 1.1244738081623316 1.119624947805457 1.14156446146091 1.2010690988092592 1.1002555653170834 1.0693483104595907 1.0 19.48187139484225 -1.5228787452803376 0.18094248700267934 1.0191824797549116 2.2586811588387166 0.7352622030264688 0.049839117700678615 32.35990254936364 0.36594481716824856 0.11582616602184562 11.042584014499521 0.029999999999999995 1.5228787452803376 1.239498679083805 TLSSSSMDLS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 TLSSSSMDLSR 11 0 Q9H0B6;Q9H0B6-2 Q9H0B6 KLC2 Kinesin light chain 2 1 TLSSSSMDLS(1)R 86.911 0.01066 4798800.0 19766.0 18726.0 18541.0 22651.0 23530.0 17014.0 14634.0 15747.0 20277.0 17200.0 True False 19484.13321535954 18682.64109752202 17016.630550329734 24316.830101520933 22146.011661759905 16286.350881571148 15391.67691528808 16478.663107249806 17993.190733723957 20172.99708244063 0.9658521803048936 0.9261212412400598 0.8435350721951811 1.2054148425316167 1.097804732299132 0.8073342208405626 0.7629841442194825 0.8168673717597215 0.8919443481893892 1.0 14.300137819214816 -6.774908848542267 24.99789431156632 0.8385775823620608 1.0050697477140258 0.3212877696797065 0.10893547056309198 282.16285492437277 523660.93069729453 0.04078928342327595 0.03616877595260804 1.6791564091839147e-07 6.774908848542267 0.16649216535196498 TLSVAAAFNEDEDS(ph)EPEEMPPEAK ddPTM_PC-9_AZD4547_30min_R2 10 TLSVAAAFNEDEDSEPEEMPPEAK 24 0 Q8WW12 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 1 TLSVAAAFNEDEDS(1)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK;T(0.001)LS(0.001)VAAAFNEDEDS(0.997)EPEEMPPEAK 108.5 1.0838e-05 6723300.0 125087.6 117847.1 146955.0 196076.0 167421.1 166293.3 139558.3 163813.1 142373.2 154581.9 True False 164862.85481628843 155938.8704493551 145006.28068130885 150873.70754400187 144177.57016354526 155894.9536628599 151978.7183397495 138499.54944555336 149898.75669135168 149170.03473206874 1.1052008877815593 1.0453766450443227 0.9720871952719016 1.0114210123701666 0.9665317194737489 1.0450822374806716 1.0188287387123396 0.9284676355698305 1.0048851765744495 1.0 17.186598230638225 -4.942691761046909 2.8503478022041633 0.9933927737148562 1.1087243522719776 0.5693487080294584 0.030587806240294023 0.22697896551442845 3.2449597270950017 0.008083029324721885 0.05162401818665768 1.1410593630267075e-05 4.942691761046909 0.1153315785571214 TLSVAAAFNEDEDS(ph)EPEEMPPEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 9 TLSVAAAFNEDEDSEPEEMPPEAK 24 0 Q8WW12 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 1 TLSVAAAFNEDEDS(1)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK;T(0.003)LS(0.001)VAAAFNEDEDS(0.996)EPEEMPPEAK;T(0.002)LSVAAAFNEDEDS(0.998)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK;T(0.001)LS(0.001)VAAAFNEDEDS(0.999)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK 95.12200000000001 0.00011822 3959120.0 54547.6 54501.7 54621.0 66596.1 71466.1 60888.0 60857.3 58341.49999999999 56187.6 48405.200000000004 True False 63781.43131579111 59912.2685868129 55923.37179129606 62864.93642446929 57462.83072869136 57694.92609280194 55092.45597530311 56810.09744292888 57009.237353504184 57180.67958464763 1.1154367485502168 1.047771188135698 0.978011667533781 1.0994086968030339 1.0049343789911773 1.0089933612522572 0.9634802589875973 0.9935191021790821 0.9970017454778646 1.0 15.8032401458559 -6.450705032506499 7.681466780380881 0.9921358258911219 1.0535003369076645 0.4431861865988188 0.03587474931976904 0.3127349928612678 29.923945531223467 0.011314058360974062 0.01279483851865967 3.542378534095212e-07 6.450705032506499 0.06136451101654261 TLSVAAAFNEDEDS(ph)EPEEMPPEAK ddPTM_PC-9_Lapatinib_30min_R1 7 TLSVAAAFNEDEDSEPEEMPPEAK 24 0 Q8WW12 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 1 TLSVAAAFNEDEDS(1)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK;TLSVAAAFNEDEDS(0.999)EPEEMPPEAK;T(0.001)LS(0.002)VAAAFNEDEDS(0.997)EPEEMPPEAK 86.57700000000001 5.271e-05 5267800.0 82632.5 73554.2 76917.9 71126.59999999999 76212.0 74555.99999999999 70866.09999999999 70016.8 76391.8 66400.8 True False 81454.1453970555 73383.8897690564 70594.00717368018 76357.48743538196 71729.35999855693 71367.41367852455 74535.19990750971 73270.03613689521 67787.75104268345 77878.08980649571 1.045918635131463 0.9422918557888864 0.906468139486801 0.9804745805284644 0.9210467305603337 0.9163991291498251 0.9570753480562748 0.9408299088864382 0.8704341774575647 1.0 16.2489298776229 -4.7641721631418275 5.2948800019204745 0.9348150966647482 1.0517412640411021 0.4627841164477583 0.03513528537230416 0.13151598726309405 10.839281995440487 0.008248496093884722 0.056641167000989014 1.7211861266337344e-05 4.7641721631418275 0.11692616737635397 TLT(ph)AEEAEEEWER ddPTM_PC-9_Lapatinib_30min_R1 1 TLTAEEAEEEWER 13 0 P35269;M0R0R9 P35269 GTF2F1 General transcription factor IIF subunit 1 1 T(0.013)LT(0.987)AEEAEEEWER 88.075 0.019691 0.0 8029.5 5403.3 7098.7 7842.9 5857.0 6438.3 6097.1 4071.7 5544.2 3841.7 True False 7914.997857570041 5390.788990827764 6515.072287774423 8419.69302914743 5512.502775305049 6162.948917410338 6412.778004660577 4260.886046471647 4919.753812985768 4505.732726256521 1.756650546857009 1.196428931395265 1.4459517871108418 1.8686623332278136 1.2234420260175924 1.36780170769931 1.4232486466165688 0.9456588540287655 1.091887626693123 1.0 12.137546022127902 -7.571545458178269 1.1267536363131498 0.9810861139113365 1.4994367808619988 0.49447687446932254 0.20585051626127737 0.44529270170526963 1.0445611188438348 0.16453900738324242 0.07333631389674547 2.681973867161377e-08 7.571545458178269 0.5183506669506623 TLT(ph)EPSVDFNHSDDFTPISTVQK ddPTM_PC-9_AZD4547_30min_R2 1 TLTEPSVDFNHSDDFTPISTVQK 23 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 T(0.124)LT(0.501)EPS(0.372)VDFNHS(0.002)DDFTPISTVQK 79.67 0.00044776 26508000.0 20860.0 17664.0 27740.0 38301.0 43154.0 35292.0 30052.0 31988.0 26336.0 34122.0 True False 27493.046085045822 23373.542561653237 27372.149475005976 29471.296194551174 37162.81199226169 33085.18566093557 32726.569781561884 27044.98961111391 27728.0671939904 32927.39916592849 0.8349595407308743 0.7098508583647545 0.8312879294556982 0.895038689391736 1.1286288298990763 1.0047919513537027 0.9939008427797598 0.821352135187726 0.8420970953175652 1.0 15.007000941935154 -5.769536889558336 3.005650298586815 0.9622754397078737 0.7751015514290609 0.4387644598303433 0.08748075225170687 0.250008828638693 4.635264095165133 0.02786658679508209 0.04848403188831767 1.7000555425012622e-06 5.769536889558336 -0.18717388827881276 TLT(ph)EPSVDFNHSDDFTPISTVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TLTEPSVDFNHSDDFTPISTVQK 23 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 T(0.231)LT(0.722)EPS(0.042)VDFNHS(0.004)DDFTPISTVQK;T(0.351)LT(0.6)EPS(0.047)VDFNHS(0.001)DDFT(0.001)PISTVQK;T(0.156)LT(0.463)EPS(0.376)VDFNHS(0.005)DDFTPISTVQK 74.3 0.00091275 28608400.0 71613.2 73100.9 61249.5 93646.0 114821.0 118692.0 123329.0 120610.0 115192.0 111028.0 True False 83735.90033482712 80357.87424498216 62709.92037002231 88399.3182244285 92322.64929944531 112467.58257467567 111646.38429536235 117444.11529685816 116876.46507814617 131156.4975028354 0.6384426385968174 0.6126869486069109 0.4781304896363721 0.6739987717537016 0.7039121283141114 0.8575067550293823 0.8512455457492583 0.8954502257451575 0.8911221884041198 1.0 17.000929755031876 -6.624642970910817 1.228198139199315 0.9117141310285484 0.5798024792074022 0.8712841592633909 0.055283437394443254 0.15324788038050666 0.4868491882519703 0.025990097441853335 0.026654522681407535 2.3733239894802705e-07 6.624642970910817 -0.3319116518211461 TLT(ph)EPSVDFNHSDDFTPISTVQK ddPTM_PC-9_Lapatinib_30min_R1 3 TLTEPSVDFNHSDDFTPISTVQK 23 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 T(0.374)LT(0.401)EPS(0.11)VDFNHS(0.115)DDFTPISTVQK;T(0.101)LT(0.393)EPS(0.359)VDFNHS(0.145)DDFT(0.002)PISTVQK;T(0.122)LT(0.672)EPS(0.205)VDFNHSDDFTPISTVQK 99.61399999999999 1.3063e-05 32698300.0 65414.0 77489.0 77910.0 79205.0 104363.0 108535.0 102231.0 95052.0 104365.0 92646.0 True False 64481.184364541536 77309.57898140993 71504.54054129706 85029.99992013439 98224.57352555245 103893.21105744221 107524.02095987517 99468.46292438594 92610.31468782868 108659.73765696482 0.5934229711478459 0.7114832103264753 0.6580592046617535 0.7825345592916051 0.9039647586454163 0.9561334611853162 0.9895479528887225 0.9154123235453095 0.8522965054470899 1.0 16.72945794338684 -6.06370578476934 1.8276076430556827 0.9410224251568338 0.6527167316223115 0.8811753657834003 0.04688110359390733 0.114056034318267 0.7599123802328798 0.015894704459858352 0.0245423793607716 8.635633754955466e-07 6.06370578476934 -0.2883056935345223 TLTAEEAEEEWERR ddPTM_PC-9_AZD4547_30min_R2 2 TLTAEEAEEEWERR 14 1 P35269;M0R0R9 P35269 GTF2F1 General transcription factor IIF subunit 1 0 ; 202.29 7.666500000000001e-09 3011200.0 9537.5 5652.299999999999 9142.4 13383.5 11788.4 8428.9 7757.7 10755.0 7671.099999999999 9320.3 False True 12570.226607676163 7479.295438249134 9021.165802461957 10298.14084801378 10151.784142595761 7901.839550534393 8448.120271343754 9093.061875313555 8076.578685138966 8993.999133878535 1.3976237289513092 0.8315872980325487 1.0030205327106483 1.1450013164024904 1.1287286102081209 0.8785679688104258 0.939306324760632 1.0110143152073332 0.8979963823563385 1.0 13.134747029737595 -6.755939316522207 24.99406246083452 0.9456859735671199 1.0831940947892342 0.23858727950800884 0.13730657758427856 230.415717655715 1047082.2460084183 0.04523865790039499 0.04400918124539026 1.754125586707095e-07 6.755939316522207 0.1375081212221143 TLTAEEAEEEWERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLTAEEAEEEWERR 14 1 P35269;M0R0R9 P35269 GTF2F1 General transcription factor IIF subunit 1 0 ; 106.26 0.00056513 2568600.0 7339.0 10622.2 10142.2 11708.8 11647.2 7974.2 10554.1 8660.400000000001 8981.2 9008.2 False True 8581.347748142738 11676.701816325813 10384.028512507699 11052.79389644177 9365.014770124786 7556.018914223184 9554.339242933003 8433.073676452299 9112.533059238911 10641.315351128042 0.8064179535129616 1.0972987296244363 0.9758218951200361 1.03866801534738 0.8800617650272003 0.7100643731437019 0.8978532190496721 0.7924841430019592 0.8563352140741632 1.0 13.377388869980871 -6.430601839388677 5.627956952680332 0.8366143807890695 0.9864019925188956 0.27069082467330263 0.09822942739099381 0.2532409520882179 12.246590352851383 0.029148512936176863 0.03291948590779597 3.7102071721193315e-07 6.430601839388677 0.14978761172982613 TLTAEEAEEEWERR ddPTM_PC-9_Lapatinib_30min_R1 2 TLTAEEAEEEWERR 14 1 P35269;M0R0R9 P35269 GTF2F1 General transcription factor IIF subunit 1 0 ; 115.34 0.00010151 2234500.0 11227.0 8824.2 13235.2 10056.3 9462.5 11942.7 9812.6 9962.6 11450.1 9142.400000000001 False True 11066.900921220358 8803.768107057233 12147.052945349442 10795.87384883338 8905.934353990779 11431.93856079345 10320.648414579453 10425.498766259401 10160.46916310168 10722.65165851774 1.0321048630195087 0.8210439346002436 1.1328403954725323 1.0068287390701045 0.8305720112539684 1.066148460741264 0.962508971032464 0.9722873686731873 0.9475705717839411 1.0 13.388374100787003 TLTDEVNS(ph)PDSDRR ddPTM_PC-9_AZD4547_30min_R2 2 TLTDEVNSPDSDRR 14 1 F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 F8VXC8 SMARCC2 SWI/SNF complex subunit SMARCC2 1 T(0.001)LTDEVNS(0.775)PDS(0.224)DRR;T(0.004)LTDEVNS(0.967)PDS(0.029)DRR 115.26 7.407300000000001e-05 61000000.0 96326.0 101856.0 99482.0 174669.0 137464.0 121632.0 103422.0 135665.0 110846.0 119720.0 True False 126955.6642947326 134778.96009735914 98162.8036796159 134401.7606591488 118379.49640135952 114026.33181205127 112626.3576450384 114701.09152156312 116705.09326340603 115528.63923993208 1.09891075606862 1.1666281277445643 0.8496837176083198 1.1633631413248162 1.0246766271998298 0.986996233680544 0.9748782499821004 0.9928368608527425 1.0101832241010877 1.0 16.81789101064723 -6.518271226004556 22.757028491125606 0.9930039325245537 1.0650067878292564 0.15985639972231214 0.08259727985232818 124.54701477987716 615163.0756734427 0.026524268355997638 0.02727505348713917 3.031997047100503e-07 6.518271226004556 0.07200285530470274 TLTDEVNS(ph)PDSDRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TLTDEVNSPDSDRR 14 1 F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 F8VXC8 SMARCC2 SWI/SNF complex subunit SMARCC2 1 T(0.01)LT(0.001)DEVNS(0.956)PDS(0.033)DRR;T(0.001)LTDEVNS(0.83)PDS(0.168)DRR;T(0.042)LT(0.001)DEVNS(0.957)PDSDRR 88.781 0.0025588 67441000.0 133100.0 156315.0 160136.0 179079.0 179255.0 160755.0 159122.0 139976.0 151638.0 114377.0 True False 155631.20115517057 171832.92015015392 163954.2495591619 169045.78421195116 144131.26954278426 152324.72480699624 144048.81221648352 136301.77831683116 153855.41887908868 135112.64469216627 1.1518625922078034 1.2717752697510232 1.2134634025757312 1.251147030665386 1.066748932871276 1.1273905943743836 1.0661386470872283 1.008801053575512 1.1387196159887552 1.0 17.043803171905992 -6.266363516341376 24.965001661666978 1.0712863353129325 1.2249988279827384 0.6940124365437885 0.05008184836875736 223.71418435000973 1134211.6969937338 0.014755764529702882 0.017250973792806983 5.415474106689477e-07 6.266363516341376 0.1537124926698059 TLTDEVNS(ph)PDSDRR ddPTM_PC-9_Lapatinib_30min_R1 3 TLTDEVNSPDSDRR 14 1 F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 F8VXC8 SMARCC2 SWI/SNF complex subunit SMARCC2 1 T(0.007)LT(0.001)DEVNS(0.991)PDS(0.001)DRR;TLTDEVNS(0.959)PDS(0.041)DRR;T(0.002)LTDEVNS(0.987)PDS(0.01)DRR 104.16 0.0005011 167073000.0 197126.0 168344.0 202524.0 158509.0 176273.0 173059.0 158791.0 161868.0 164206.0 152972.0 True False 194314.94709151852 167954.20981102478 185873.2584852477 170166.280630523 165904.96870605214 165657.6699902328 167012.4210096697 169388.9782081865 145711.39111416278 179413.0063776222 1.0830594225846215 0.9361317398445498 1.0360077133651515 0.9484612295741981 0.9247098192918143 0.9233314425463801 0.9308824615432162 0.944128754253538 0.8121562313463192 1.0 17.452924955308987 -1.5228787452827452 0.4187428961729694 0.9145930718325487 3.593309241096784 0.3985352765212319 0.053953070842152444 78.26984157568698 1.0052623107541132 0.035177324607166646 175.4622037071477 0.029999999999833684 1.5228787452827452 2.678716169264235 TLTDEVNS(ph)PDSDRRDK ddPTM_PC-9_AZD4547_30min_R2 1 TLTDEVNSPDSDRRDK 16 2 F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 F8VXC8 SMARCC2 SWI/SNF complex subunit SMARCC2 1 T(0.003)LT(0.003)DEVNS(0.983)PDS(0.011)DRRDK 49.34 0.032267000000000004 5251800.0 20384.0 13936.0 21022.0 49147.0 37062.0 21610.0 17131.0 17966.0 17205.0 29089.0 True False 26865.68798646089 18440.53946666665 20743.234544469207 37816.91846358076 31916.58103668726 20258.72328382686 18655.625812855607 15189.767517608867 18114.421175296357 28070.60296400251 0.9570755576897727 0.6569342130026431 0.7389664757493861 1.347207201501045 1.137010882082469 0.7217060249758961 0.6645965473837314 0.5411272261264957 0.6453164258183598 1.0 14.776772433205139 -6.901927886261492 7.570899207051141 0.6772404003068488 0.9579914754168118 0.25698854543541827 0.2112256087007157 0.3342898949157911 22.59736519875772 0.08095524802424442 0.07139635170711857 1.253349273828129e-07 6.901927886261492 0.280751075109963 TLTDEVNSPDS(ph)DRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLTDEVNSPDSDRR 14 1 F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 F8VXC8 SMARCC2 SWI/SNF complex subunit SMARCC2 1 TLTDEVNS(0.014)PDS(0.986)DRR;TLTDEVNS(0.218)PDS(0.782)DRR 114.21 0.00025975 27114600.0 174539.0 189997.0 185647.0 218986.0 235092.0 190135.0 201924.0 205776.0 174878.0 158828.0 True False 204085.00539761348 208858.64651357091 190073.52855016786 206716.92438219124 189027.41022204224 180163.9858864622 182796.29691683812 200374.5980376942 177435.25991332758 187622.25911824344 1.087744100069677 1.1131869293927639 1.0130649180083668 1.1017718545426636 1.0074892558612314 0.9602484626992959 0.9742783067207186 1.0679681556942238 0.9457047407232433 1.0 17.517471470810953 -6.36957281825792 5.2533254502808395 0.9921630663370602 1.076415303314573 0.5375538162303419 0.039380460407051635 0.18879803373754733 7.636302115369831 0.012260758118632555 0.013939177356407196 4.269993183620952e-07 6.36957281825792 0.08425223697751272 TLTDEVNSPDS(ph)DRR ddPTM_PC-9_Lapatinib_30min_R1 1 TLTDEVNSPDSDRR 14 1 F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 F8VXC8 SMARCC2 SWI/SNF complex subunit SMARCC2 1 TLTDEVNS(0.01)PDS(0.99)DRR 136.57 8.4425e-05 37863000.0 33359.0 31291.0 51701.0 33713.0 43078.0 39111.0 35043.0 40373.0 41847.0 31758.0 True False 32883.294542708645 31218.54761201331 47450.34335163136 36192.366483271166 40544.23673460658 37438.31370219402 36857.35507328413 42248.876968882694 37133.75019155431 37247.327985124975 0.8828363354236003 0.8381419366371916 1.273926102043643 0.9716768541819935 1.0885139667145587 1.0051275011497554 0.9895301775204766 1.1342794034985577 0.9969507129849415 1.0 15.184849314094025 -5.161994887075938 24.553194936995954 1.056087016090655 0.8604838380751613 0.4482700361201075 0.08741496192528526 31.23675013033666 7707.860068423683 0.020849752162986273 0.05516328406668252 6.886604038560441e-06 5.161994887075938 -0.19560317801549376 TLTDGVLDINHEQENT(ph)PSTSGK ddPTM_PC-9_AZD4547_30min_R2 1 TLTDGVLDINHEQENTPSTSGK 22 0 A0A2R8Y7R9;Q13136-2;Q13136;E9PJZ7 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 TLTDGVLDINHEQENT(0.99)PS(0.007)T(0.002)S(0.001)GK 78.55199999999999 0.0013469 3391000.0 10531.0 10199.0 14141.0 18703.0 17472.0 15393.0 12318.0 16090.0 12475.0 15863.0 True False 13879.638941592404 13495.627297684638 13953.481100434732 14391.312308469505 15046.314388673034 14430.473276628732 13414.278136872064 13603.660211417478 13134.403031782738 15307.641198321417 0.9067131089481244 0.881626837397033 0.9115369846769614 0.9401391188896959 0.9829283423707998 0.9426973816325881 0.8763125528669321 0.8886842874857303 0.8580291934999764 1.0 13.901964370181894 -6.007604735219325 0.0044810526139040215 1.8254021136861933 5.202673423323421e-08 0.09298706224957076 0.04229026307583624 82563.61565624653 92.67946978349579 18500.635983313936 19254.675076578173 9.826418687856578e-07 6.007604735219325 -1.825402061659459 TLTDGVLDINHEQENT(ph)PSTSGK ddPTM_PC-9_Lapatinib_30min_R1 1 TLTDGVLDINHEQENTPSTSGK 22 0 A0A2R8Y7R9;Q13136-2;Q13136;E9PJZ7 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 TLTDGVLDINHEQENT(0.87)PS(0.09)T(0.03)S(0.01)GK 96.53299999999999 0.0038985 0.0 19265.0 14456.0 19751.0 14491.0 13616.0 14005.0 14324.0 10916.0 13508.0 9857.2 True False 18990.277567231682 14422.52802017399 18127.149021064804 15556.71648055891 12815.133650085974 13406.038797249554 15065.626632129726 11423.197210817225 11986.586794453975 11561.003886106613 1.6426149281078581 1.2475151952423613 1.5679563124141 1.3456198643142163 1.1084793134172808 1.1595912369997732 1.303141732374537 0.9880800424732149 1.0368119336815382 1.0 13.496979057545916 -5.720630467527809 0.3398922804096229 0.9754225737864052 1.7426286138818334 0.674452807150621 0.1238230377124137 2.239649035375895 0.3350900620680801 0.13511918958872265 0.6720198582444641 1.9026965577200224e-06 5.720630467527809 0.7672060400954283 TLTEPS(ph)VDFNHSDDFTPISTVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLTEPSVDFNHSDDFTPISTVQK 23 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 T(0.007)LT(0.007)EPS(0.981)VDFNHS(0.006)DDFTPISTVQK 98.684 3.9537e-06 16273000.0 17162.0 17129.0 14170.0 21336.0 26448.0 25844.0 34220.0 25879.0 32167.0 25263.0 True False 20067.18763504915 18829.45391838271 14507.866540024259 20140.613092245287 21265.70425855659 24488.695144238165 30978.433868654567 25199.703671067036 32637.381521014773 29842.981918202047 0.6724256875553588 0.6309508201959575 0.48613997688935756 0.6748860803337142 0.712586440485227 0.8205847261295911 1.0380475367228628 0.84440970879311 1.0936367421483557 1.0 14.865104076793635 -6.823784814789849 1.3673211104273466 0.9915467045463333 0.603341515710762 0.8276049765317655 0.0778850879421694 0.16434738052541997 0.6406147442637896 0.03696188282910367 0.031594059650827934 1.5004280868483687e-07 6.823784814789849 -0.3882051888355713 TLTEPS(ph)VDFNHSDDFTPISTVQK ddPTM_PC-9_Lapatinib_30min_R1 1 TLTEPSVDFNHSDDFTPISTVQK 23 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 T(0.005)LT(0.02)EPS(0.975)VDFNHSDDFTPISTVQK 92.805 7.7513e-06 16424000.0 27134.0 21490.0 35126.0 39644.0 46940.0 75824.0 69577.0 63303.0 96056.0 50362.0 True False 26747.064184233815 21440.241225341662 32238.075870281093 42559.55200850717 44179.08148759073 72581.18427437697 73179.35661712445 66244.28847896312 85237.16176547762 59067.00459685316 0.45282580971879494 0.36298169124499513 0.5457882296607707 0.7205300539444413 0.7479485677176934 1.2287940580322534 1.2389210713594088 1.121510882955665 1.4430588168003815 1.0 15.850064831482339 -6.381802185435411 1.112721901626029 1.2390354527922751 0.4218340384744861 0.8646226971228965 0.12978342892564187 0.15782373903415084 0.409879591142369 0.05611769912182236 0.07416493995635498 4.1514309097259286e-07 6.381802185435411 -0.817201414317789 down TLTEPSVDFNHS(ph)DDFTPISTVQK ddPTM_PC-9_AZD4547_30min_R2 1 TLTEPSVDFNHSDDFTPISTVQK 23 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 T(0.005)LT(0.033)EPS(0.089)VDFNHS(0.858)DDFT(0.014)PIS(0.001)TVQK 69.952 0.0010577 28152000.0 29379.0 30920.0 34624.0 49042.0 58281.0 51186.0 49015.0 43061.0 43523.0 49949.0 True False 38720.91087883805 40914.28532644467 34164.863137080305 37736.12459134692 50189.68915328827 47985.33132836474 53377.24004536319 36406.91189334048 45823.53692603445 48200.30071329238 0.8033333880873451 0.8488387981189831 0.7088101657353049 0.7829022647765408 1.0412733615881211 0.9955400820794389 1.1074047102499331 0.755325409895221 0.950689855621534 1.0 15.556754526756187 -6.247600635750563 24.434390284429643 0.970448520808164 0.7849501771805499 0.5104145393283548 0.09064523660697377 531.9450154180793 939228.2757945263 0.02804905822403349 0.03600900511703697 5.654567129320279e-07 6.247600635750563 -0.18549834362761408 TLTLVDTGIGMTK ddPTM_PC-9_Lapatinib_30min_R1 3 TLTLVDTGIGMTK 13 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 ;; 231.92 9.634e-20 38953000.0 174102.0 155221.0 180734.0 162634.0 186042.0 173770.0 164558.0 150120.0 161840.0 151759.0 False True 171619.27355360374 154861.59531124998 165874.74817341557 174594.64689112006 175099.37533264517 166338.2621776546 173078.00805152196 157095.1232400034 143611.8749492472 177990.3409438433 0.9642055442084373 0.8700561754646533 0.9319311783651775 0.9809220318657933 0.9837577387858916 0.9345353309376211 0.9724011265652264 0.8826047661179972 0.806852069543242 1.0 17.441439426580622 -10.604562041994205 4.9045198974335475 1.0000004429255236 0.9275884186428368 0.1451484606327258 0.05415379271215898 1.4121140730179816e-06 2.6443585528570903e-07 0.05510150882865225 0.013363660101050468 2.4856384480837368e-11 10.604562041994205 -0.07241202428268678 TLTPSY(ph)Y(ph)RGAQGVILVYDVT(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 TLTPSYYRGAQGVILVYDVTR 21 1 A0A087X163;H0Y6T8;Q9NP72;Q9NP72-2 A0A087X163 RAB18 Ras-related protein Rab-18 3 T(0.308)LT(0.358)PS(0.385)Y(0.474)Y(0.474)RGAQGVILVY(0.163)DVT(0.837)R 47.018 0.042376 12014000.0 1054.3 979.8 49134.0 3113.9 4403.4 13813.0 1146.4 960.27 28922.0 823.01 True False 1039.2654886650587 977.531333298732 45094.39218272483 3342.9065936658867 4144.400669417492 13222.250189675686 1205.7549826217194 1004.8876498379863 25664.499797838147 965.2661819081083 1.0766620732642584 1.0127064965296706 46.71705383232595 3.4631966356241057 4.293531408326116 13.698035254418995 1.2491424699435967 1.0410471936886418 26.58800264514122 1.0 9.914783024762002 TLVLLMGK ddPTM_PC-9_Lapatinib_30min_R1 2 TLVLLMGK 8 0 P07737;K7EJ44;CON__P02584 P07737 PFN1 Profilin-1 0 ; 141.78 0.0099803 11350800.0 89552.0 82426.0 100907.0 78834.0 82743.0 82192.0 87282.0 78650.0 74754.0 85928.0 False True 88274.97205817439 82235.14766123821 92610.81597228421 84631.71534251468 77876.21941899699 78676.83975890996 91801.03488589414 82304.36612594109 66334.41732548217 100780.54030813712 0.8759128675860749 0.8159824050337867 0.9189354977570677 0.8397624688630632 0.7727307194512946 0.7806749152004449 0.9109004040384375 0.8166692287449043 0.6582066053889399 1.0 16.62085757050467 -5.9979034924563885 24.908091270195964 0.8153765138724134 0.8672643935037005 0.050273307053040006 0.08735679862446867 192.7186954196073 2289552.090988778 0.02394913431318418 0.035256331927535 1.004839057621928e-06 5.9979034924563885 0.05188787963128716 TLVLSSS(ph)PTSPTQEPLPGGK ddPTM_PC-9_AZD4547_30min_R2 2 TLVLSSSPTSPTQEPLPGGK 20 0 H0YI02;J3KPG1;Q96QF0-8;Q96QF0-5;Q96QF0-7;Q96QF0-6;Q96QF0-3;Q96QF0-4;Q96QF0-2;Q96QF0 H0YI02 RAB3IP Rab-3A-interacting protein 1 TLVLS(0.014)S(0.079)S(0.479)PT(0.354)S(0.028)PT(0.046)QEPLPGGK;TLVLSS(0.002)S(0.911)PT(0.082)S(0.005)PTQEPLPGGK 253.36 9.219199999999997e-138 4687900.0 42762.0 39768.0 54173.0 76447.0 68961.0 64755.0 49703.0 68911.0 49481.0 53018.0 True False 56359.42649514524 52622.22829437424 53454.63062399058 58823.325244376254 59386.95550350745 60705.85961333677 54126.470712530616 58262.38836724621 52096.46464253642 51161.85595742324 1.1015907347467497 1.0285441626309708 1.0448141417792853 1.1497496356138617 1.160766246496787 1.1865452978065538 1.0579458016060739 1.1387856690682217 1.0182676853218726 1.0 15.642780980203788 -8.355538785829223 5.367803879514395 1.002729272085033 1.1076998857535294 0.39234691149781986 0.049601044964626036 0.2628736859389341 11.268290801438601 0.05225580716465935 0.013651132897422048 4.4102297462737e-09 8.355538785829223 0.10497061366849647 TLVLSSS(ph)PTSPTQEPLPGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLVLSSSPTSPTQEPLPGGK 20 0 H0YI02;J3KPG1;Q96QF0-8;Q96QF0-5;Q96QF0-7;Q96QF0-6;Q96QF0-3;Q96QF0-4;Q96QF0-2;Q96QF0 H0YI02 RAB3IP Rab-3A-interacting protein 1 TLVLS(0.001)S(0.03)S(0.968)PT(0.001)SPTQEPLPGGK 241.11 6.050399999999999e-119 0.0 13527.0 11974.0 13144.0 14438.0 20664.0 15877.0 15707.0 18869.0 14045.0 13657.0 True False 15816.853929571706 13162.699586590837 13457.402808897581 13629.08566862756 16615.03753776517 15044.382170138884 14219.11925116766 18373.70874335809 14250.381554470501 16132.905991247484 0.9804094772604982 0.815891420537127 0.8341586330570926 0.8448004145081914 1.0298849783652897 0.9325277280051621 0.8813737127633359 1.138896411677245 0.8833115101644862 1.0 13.977718711505428 -6.250547597156368 24.75216709736313 0.9775390439967613 0.8625592714196884 0.29798972550388103 0.08162226807654677 778.7261646445862 1769696.470819292 0.02356221289830348 0.030099693385579364 5.616327220003751e-07 6.250547597156368 -0.11497977257707293 TLVLSSS(ph)PTSPTQEPLPGGK ddPTM_PC-9_Lapatinib_30min_R1 1 TLVLSSSPTSPTQEPLPGGK 20 0 H0YI02;J3KPG1;Q96QF0-8;Q96QF0-5;Q96QF0-7;Q96QF0-6;Q96QF0-3;Q96QF0-4;Q96QF0-2;Q96QF0 H0YI02 RAB3IP Rab-3A-interacting protein 1 TLVLSS(0.015)S(0.952)PT(0.031)S(0.002)PT(0.001)QEPLPGGK 188.27 1.5332e-47 0.0 15099.0 12484.0 14105.0 10834.0 12197.0 15932.0 14023.0 13113.0 14673.0 11391.0 True False 14883.685491182523 12455.09406501468 12945.34134687453 11630.768501164537 11479.596440224635 15250.625499305945 14749.042324934035 13722.277851360039 13020.372226460107 13359.919172446576 1.1140550552041177 0.932273160057884 0.9689685378915264 0.8705717715083015 0.8592564290284099 1.1415207908412164 1.1039769129256694 1.0271228196994477 0.9745846556701668 1.0 13.705623659078238 -6.760999533569482 24.999998409947906 1.054544696259532 0.9448438040531598 0.2861519881045227 0.07895766110762396 15.599742297266191 886676.7481716604 0.02815126719605602 0.026532846727367908 1.7338058598536233e-07 6.760999533569482 -0.10970089220637214 TLVLSSSPT(ph)SPTQEPLPGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLVLSSSPTSPTQEPLPGGK 20 0 H0YI02;J3KPG1;Q96QF0-8;Q96QF0-5;Q96QF0-7;Q96QF0-6;Q96QF0-3;Q96QF0-4;Q96QF0-2;Q96QF0 H0YI02 RAB3IP Rab-3A-interacting protein 1 TLVLSS(0.003)S(0.026)PT(0.963)S(0.008)PTQEPLPGGK 209.23 7.908799999999999e-73 0.0 14212.0 14665.0 14005.0 14726.0 20858.0 18747.0 19858.0 14600.0 16770.0 13914.0 True False 16617.810900205015 16120.844282391396 14338.932314258274 13900.94996233616 16771.024630405816 17763.874317792637 17976.906480530186 14216.765469978687 17015.229524276983 16436.49805683661 1.0110311115385668 0.9807955579495279 0.8723836588958879 0.8457367204539161 1.0203526671199927 1.0807578509951465 1.093718772597844 0.8649510023861411 1.0352101442435697 1.0 14.004615332205958 -6.308630477910117 24.689960062417054 1.0162199880079232 0.9273585564573706 0.26027089011943594 0.07296250657562019 536.4745620849171 280677.23850936425 0.02432543592906077 0.027582530866921702 4.913257458400841e-07 6.308630477910117 -0.0888614315505526 TLVVHEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TLVVHEK 7 0 P00441;H7BYH4 P00441 SOD1 Superoxide dismutase [Cu-Zn] 0 70.919 0.035878 7603200.0 66572.0 65997.0 74774.0 83221.0 85509.0 75064.0 87323.0 79359.0 78667.0 68745.0 False True 77841.32474306556 72548.74600102202 76556.89574197421 78558.39717612226 68754.12528149263 71127.51169738022 79051.13327622799 77275.91033781074 79817.35605165745 81207.92431487946 0.9585434598874848 0.893370278985559 0.9427269122792606 0.9673735394530736 0.8466430568389128 0.8758691014141309 0.9734411258895299 0.9515809077717274 0.9828764461725416 1.0 16.30933289282163 -7.289313910553421 23.258677628841433 0.9729397314576502 0.9138042224384044 0.413625440255056 0.03655473010755141 359.18699848301105 299705.307859639 0.01611897819123994 0.010866175454344665 5.136722321179736e-08 7.289313910553421 -0.0591355090192458 TLVVHEK ddPTM_PC-9_Lapatinib_30min_R1 1 TLVVHEK 7 0 P00441;H7BYH4 P00441 SOD1 Superoxide dismutase [Cu-Zn] 0 86.01100000000001 0.015862 16374000.0 129880.0 115280.0 121750.0 114790.0 115200.0 104400.0 126130.0 114180.0 109330.0 102380.0 False True 128027.88738292521 115013.07624278183 111740.18496859114 123232.03952821449 108424.16249191409 99935.05536828648 132660.39424117023 119485.21963458344 97016.10410406072 120076.2465872249 1.0662215968744837 0.9578337057632367 0.9305769304457869 1.0262815755045873 0.9029609566714213 0.832263317755293 1.1048013075992016 0.9950779028372432 0.8079541696332672 1.0 16.873591260616735 -4.76280640576477 5.575781387834697 0.951681651905467 1.0714647966152284 0.1447208332033182 0.08424186264345944 0.3049580928410649 31.008965758445218 0.020978916806755708 0.1408792719649939 1.7266073854099174e-05 4.76280640576477 0.11978314470976137 TLYGFGG ddPTM_PC-9_Lapatinib_30min_R1 1 TLYGFGG 7 0 P62805 P62805 HIST1H4A Histone H4 0 50.12 0.04514 2454600.0 36078.0 27892.0 21322.0 19964.0 17955.0 19814.0 56149.0 17396.0 23939.0 20539.0 False True 35563.521104105115 27827.417787679376 19568.987465300164 21432.219157951702 16898.92220088819 18966.601408689934 59056.120480833015 18204.28166722027 21242.737731154397 24089.138783502774 1.4763301180555473 1.1551852491603696 0.8123572885346074 0.88970466526721 0.7015162456725628 0.7873507467057742 2.4515662851872917 0.7557049602656325 0.8818388204771476 1.0 14.556095195916228 TLYS(ph)FFSPSPAR ddPTM_PC-9_Lapatinib_30min_R1 1 TLYSFFSPSPAR 12 0 P13051 P13051 UNG Uracil-DNA glycosylase 1 TLYS(0.517)FFS(0.459)PS(0.023)PAR 66.32600000000001 0.039522 9890100.0 29370.0 22967.0 19077.0 23969.0 23439.0 21130.0 16126.0 17837.0 19112.0 19128.0 True False 28951.178414201622 22913.82132258828 17508.562699349568 25731.760218240037 22060.36410284701 20226.319156435766 16960.925374876006 18665.77213716991 16959.405301717834 22434.24931354211 1.2904901790819299 1.0213767798665179 0.7804389821406138 1.1469855691898472 0.9833341777801582 0.9015821690198673 0.756028211054862 0.8320212491310145 0.7559604542453103 1.0 14.453415289449621 -6.819036929126981 2.650625821850396 0.8226927060421991 1.0389067487559331 0.34973115417706135 0.1358076731773464 0.32415097427173933 4.648466310124917 0.0524358856179632 0.046968079559102066 1.5169213744231428e-07 6.819036929126981 0.216214042713734 TLYSFFS(ph)PSPAR ddPTM_PC-9_AZD4547_30min_R2 2 TLYSFFSPSPAR 12 0 P13051 P13051 UNG Uracil-DNA glycosylase 1 TLYSFFS(0.999)PS(0.001)PAR;TLYSFFS(0.981)PS(0.019)PAR 185.2 0.00041653 20385700.0 22223.4 26351.0 44567.0 65031.0 53746.0 51342.0 56209.0 60467.0 49722.0 53040.0 True False 29289.97892456413 34868.445428109415 43976.01246043949 50039.107668934426 46284.29562349019 48131.57662370379 61211.49210873855 51123.214543429516 52350.20341052512 51183.08574411951 0.5722589503687611 0.6812493799695438 0.8591903325307413 0.9776492945168607 0.9042888866622866 0.9403805168044931 1.1959320392434765 0.9988302541783176 1.022802799976547 1.0 15.643379507261715 -4.676475431148069 0.6105465919462618 1.0424127801546865 0.17308376074759438 0.8360593978138953 0.0683189428875529 1.5664660053208541 0.4041731710470528 0.03528945680577376 0.9877868955819081 2.1063210541463016e-05 4.676475431148069 -0.8693290194070922 TLYSFFS(ph)PSPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLYSFFSPSPAR 12 0 P13051 P13051 UNG Uracil-DNA glycosylase 1 TLYS(0.019)FFS(0.976)PS(0.005)PAR;TLYSFFS(0.999)PS(0.001)PAR 173.59 0.0011654999999999999 17332400.0 15640.300000000001 21004.9 25643.0 27318.0 28187.0 28481.4 27228.0 32646.0 26520.0 19500.9 True False 18287.89387999412 23090.12765545197 26254.42637161906 25787.461026150962 22663.95969207255 26987.78524536083 24648.76672635089 31789.07709129621 26907.804829089175 23036.25880096055 0.7938743021601913 1.0023384376324673 1.139700096203309 1.119429211529595 0.9838385602408461 1.1715350777460232 1.069998689427951 1.379958324221062 1.1680631417444916 1.0 14.491618814751547 -4.143861862818779 0.9480941441293278 1.1466591980897607 9.27139744977917e-16 0.48852319630891217 0.10481447633695083 5.118318186059206 1.5511936868870966 0.035592363396632916 8.055840386510592 7.180226382916339e-05 4.143861862818779 -1.1466591980897598 TLYSFFS(ph)PSPAR ddPTM_PC-9_Lapatinib_30min_R1 3 TLYSFFSPSPAR 12 0 P13051 P13051 UNG Uracil-DNA glycosylase 1 T(0.001)LYS(0.016)FFS(0.799)PS(0.184)PAR;TLYSFFS(0.987)PS(0.013)PAR;TLYS(0.001)FFS(0.761)PS(0.238)PAR 149.82 0.00016677 23778000.0 75661.0 60055.0 82190.0 64782.0 77368.0 64690.0 52748.0 57052.0 69835.0 54310.0 True False 74582.06026547174 59915.94633726818 75432.65546257485 69546.28438641678 72817.36635134042 61923.35949975536 55479.03334205379 59702.84419856579 61969.44690484847 63697.41113647384 1.1708805575422394 0.940633932655383 1.1842342430677104 1.0918227781253391 1.1431762304330826 0.972148763896895 0.870977836496182 0.9372883941962797 0.9728723004468243 1.0 15.958947117549556 -6.870143943419468 5.361477102722758 0.9379186953000824 1.1000221387714373 0.5506763593063021 0.0701821519869576 0.157547081291491 6.8377162411884385 0.024305002440818943 0.0214600665025718 1.348515853759975e-07 6.870143943419468 0.16210344347135486 TLYSFFSPS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 2 TLYSFFSPSPAR 12 0 P13051 P13051 UNG Uracil-DNA glycosylase 1 TLYS(0.001)FFS(0.028)PS(0.971)PAR;TLYS(0.015)FFS(0.194)PS(0.791)PAR 81.327 0.013324 16074600.0 45849.0 35953.0 48574.0 66124.0 63493.0 54517.0 51007.0 59693.0 47318.0 52482.0 True False 60428.02828155639 47574.104150765386 47929.87702231222 50880.133405616085 54678.09291895702 51108.04337179029 55546.524186347895 50468.818458678914 49819.13287838844 50644.62115427754 1.1931776150023095 0.9393713106440561 0.9463962002263684 1.0046502915012654 1.0796426485725386 1.0091504725862406 1.0967902004269674 0.996528699561932 0.9837003761292944 1.0 15.628121431475718 -9.780431259767074 0.00412996311797941 6.4109427378118e-05 2.0168649528903217 0.0358506440441585 0.07198201747228943 143593.70512604914 155.85998544034044 38722.14998830059 37390.659342142986 1.6579397351740338e-10 9.780431259767074 2.0168008434629434 TLYSFFSPS(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TLYSFFSPSPAR 12 0 P13051 P13051 UNG Uracil-DNA glycosylase 1 TLYSFFS(0.006)PS(0.994)PAR;TLYS(0.001)FFS(0.038)PS(0.961)PAR 88.78 0.0078491 13221200.0 30142.0 25736.2 31682.0 28134.0 41126.0 39464.0 40319.0 34683.0 35116.0 25089.0 True False 35244.4452683633 28291.119851379586 32437.41903465408 26557.743191658676 33067.65552546123 37394.43836759847 36499.69243571841 33772.607999676104 35629.50506705492 29637.437095585294 1.1891866747686226 0.9545737629112927 1.0944744962271338 0.896087711835739 1.1157393744544428 1.2617298266039556 1.231540106453918 1.139525252833241 1.202179019465964 1.0 14.855133075190652 -6.517790331622628 24.621239542882094 1.1807476361638929 1.02899019968724 0.284319282136854 0.09854860137311117 201.102485334603 973078.2307306055 0.030270616248626016 0.031116910181759275 3.0353562376166725e-07 6.517790331622628 -0.15175743647665296 TMDASER ddPTM_PC-9_Lapatinib_30min_R1 1 TMDASER 7 0 P00352;Q5SYQ7;Q5SYQ9;Q5SYQ8 P00352 ALDH1A1 Retinal dehydrogenase 1 0 84.568 0.039202 0.0 56839.0 47014.0 46718.0 48722.0 74578.0 55062.0 73238.0 91346.0 77837.0 61670.0 False True 56028.465437003964 46905.14197153153 42877.02637669509 52305.17841182743 70191.46866598944 52707.12661579114 77029.90528371384 95590.26863496794 69070.17740005282 72329.5773298903 0.7746273033155155 0.648491857730626 0.5928007318656914 0.7231506161479012 0.9704393590723047 0.7287077923239826 1.0649848668738333 1.3215930766329134 0.954936831512625 1.0 16.142298100603373 -6.911316313234923 1.0868085134942842 1.1160526586746038 0.6801825522078596 0.6054708268402991 0.13354680718845668 0.32510220224053915 0.8032674152884177 0.07924656652690225 0.061866655188892214 1.226545565837272e-07 6.911316313234923 -0.4358701064667442 TMFAQVES(ph)DDEEAKNEPEWK ddPTM_PC-9_Lapatinib_30min_R1 1 TMFAQVESDDEEAKNEPEWK 20 1 Q9NW82 Q9NW82 WDR70 WD repeat-containing protein 70 1 T(0.01)MFAQVES(0.99)DDEEAKNEPEWK 60.56399999999999 0.0063113 8791200.0 12174.0 10196.0 7750.8 7524.4 11072.0 9262.2 8097.4 8654.8 7848.3 9045.0 True False 12000.396527561825 10172.391788440369 7113.55914295322 8077.769476662577 10420.766728389537 8866.077297242759 8516.643751117512 9056.933603900776 6964.341807737132 10608.416198295086 1.131214716998985 0.9588982557146662 0.6705580748327411 0.761449148079313 0.9823112643397507 0.8357588099407012 0.8028195342190901 0.8537498373561498 0.6564921358247986 1.0 13.372921662246597 -4.956925422815081 4.057631601260532 0.8180106560752576 1.1166136387332646 0.4520958291392232 0.1068891145619712 0.18882374187934023 6.541394746400981 0.026748471757084905 0.12380115698216254 1.1042682289090576e-05 4.956925422815081 0.298602982658007 TMIIS(ph)PER ddPTM_PC-9_AZD4547_30min_R2 2 TMIISPER 8 0 O75533;B4DGZ4;A0A494C1M2;O75533-2 O75533 SF3B1 Splicing factor 3B subunit 1 1 T(0.001)MIIS(0.999)PER;T(0.005)MIIS(0.995)PER 78.939 0.020612000000000002 19402000.0 97282.0 134143.0 125582.0 106530.0 112343.0 142024.0 118480.0 157200.0 118548.0 111596.0 True False 128215.65240869772 177502.10144066194 123916.70062617876 81971.1543720931 96746.11363133571 133143.216828423 129024.49047382713 132908.3520966331 124814.20525946116 107689.05800717881 1.1906098426466927 1.6482835371150635 1.150689800053021 0.7611836883801946 0.898383878749189 1.236367178729963 1.1981207084681347 1.2341862261231138 1.159024023138365 1.0 16.71651214343929 -5.500102864652598 23.71474948337089 1.0746434345807012 1.4144568961084096 0.3774427069274834 0.17710270463128877 422.51090150016324 439925.70347702905 0.04951288185543139 0.10170206800011444 3.1615287488036054e-06 5.500102864652598 0.3398134615277084 TMIIS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 3 TMIISPER 8 0 O75533;B4DGZ4;A0A494C1M2;O75533-2 O75533 SF3B1 Splicing factor 3B subunit 1 1 TMIIS(1)PER;TMIIS(1)PER;T(0.001)MIIS(0.999)PER 89.08 0.010494 25526800.0 44494.0 56534.0 51914.0 46803.0 56068.0 59066.0 59599.0 53146.0 54819.0 40776.0 True False 43859.50740079972 56403.09899643858 47645.83131383514 50245.04875023108 52770.190473929186 56539.88486957099 62684.74459985332 55615.3571790117 48644.7069503385 47824.07726939526 0.9171009647240461 1.1793870831781508 0.9962728824948142 1.0506224399730364 1.1034230765535158 1.1822472716217645 1.3107361015403858 1.1629154257535967 1.017159341649617 1.0 15.54544951264337 -6.4527051633629116 3.2257605423897187 1.155219140414895 1.0435265184044848 0.1550140065616974 0.10249185342335534 0.4301687333866405 8.74219981243841 0.034202254211777125 0.038021198698628064 3.526101720705229e-07 6.4527051633629116 -0.11169262201041019 TMLLLSRS(ph)PEAQPK ddPTM_PC-9_Lapatinib_30min_R1 1 TMLLLSRSPEAQPK 14 1 P55265-5;P55265;P55265-4 P55265-5 ADAR Double-stranded RNA-specific adenosine deaminase 1 T(0.001)MLLLS(0.002)RS(0.998)PEAQPK 81.278 0.005005600000000001 3724100.0 49537.0 12447.0 25593.0 21039.0 13587.0 14059.0 10412.0 10739.0 22359.0 9378.6 True False 48830.59329602677 12418.179736241404 23488.84233183695 22586.27824404657 12787.839373069774 13457.729343129704 10951.082413692733 11237.97314464695 19840.693969292 10999.678513801022 4.4392745874127355 1.1289584255267664 2.1354117124756042 2.053358033665087 1.162564829237981 1.2234656973151194 0.9955820435981546 1.021663781404788 1.8037521682473152 1.0 13.425173738451864 -4.758188338772103 24.999816078223837 1.4114472612394473 4.439278765083693 0.8259057517209113 0.41968107089721757 38.75617256164324 297977.7637477768 0.11161601075117948 0.779755257657846 1.7450652132664314e-05 4.758188338772103 3.027831503844246 TMPNSS(ph)TPTSQINTIDSR ddPTM_PC-9_AZD4547_30min_R2 1 TMPNSSTPTSQINTIDSR 18 0 Q92547 Q92547 TOPBP1 DNA topoisomerase 2-binding protein 1 1 TMPNS(0.121)S(0.43)T(0.43)PT(0.009)S(0.009)QINTIDSR 95.18299999999999 0.00080304 4804400.0 10563.0 7207.2 13650.0 17100.0 15834.0 13418.0 12084.0 18564.0 10026.0 12252.0 True False 13921.814275951067 9536.786455522377 13468.992081248445 13157.859192366392 13635.722414734943 12578.970338842613 13159.45259019012 15695.3603582818 10555.953891515326 11823.061209218562 1.177513507677359 0.8066258210763932 1.1392135964538976 1.1128978324249115 1.1533157253810908 1.0639351447351606 1.113032602751778 1.3275208577998368 0.8928274754498218 1.0 13.529316003860723 TMPNSSTPTS(ph)QINTIDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TMPNSSTPTSQINTIDSR 18 0 Q92547 Q92547 TOPBP1 DNA topoisomerase 2-binding protein 1 1 TMPNSS(0.174)T(0.004)PT(0.258)S(0.564)QINTIDSR 157.7 1.0643e-17 0.0 11089.0 10742.0 10626.0 11593.0 13758.0 12133.0 11011.0 10002.0 10684.0 7896.2 True False 12966.148682266627 11808.39476859519 10879.364139329407 10943.48179501311 11062.218662629364 11496.724121074212 9967.958367263462 9739.458097994999 10840.233287857805 9327.718553715196 1.390066457044017 1.265946726479215 1.1663478134206993 1.1732216974593814 1.1859511625405252 1.232533341874376 1.0686384146199672 1.0441415059758432 1.1621526984795418 1.0 13.187308543259988 -1.5228787452803376 0.20399298047743641 1.0246408911983085 2.603815489054735 0.7348108501422514 0.055675241482077795 29.422207429240476 0.3598837058936952 0.1046593806542748 14.939207719758077 0.029999999999999995 1.5228787452803376 1.5791745978564264 TMPNSSTPTS(ph)QINTIDSR ddPTM_PC-9_Lapatinib_30min_R1 1 TMPNSSTPTSQINTIDSR 18 0 Q92547 Q92547 TOPBP1 DNA topoisomerase 2-binding protein 1 1 T(0.046)MPNS(0.147)S(0.115)T(0.01)PT(0.242)S(0.437)QINT(0.002)IDSR 131.31 1.0646e-05 0.0 10298.0 9478.8 10513.0 8072.0 8427.3 9039.2 6161.2 7101.2 7817.7 5741.3 True False 10151.148631578095 9456.852420975734 9648.661721353565 8665.641807402633 7931.622782709272 8652.614487404362 6480.196789016869 7431.147676205135 6937.188301969409 6733.676055198629 1.5075195997498365 1.404411549271771 1.4328966291606005 1.2869110031974973 1.1779038251455216 1.2849763511751129 0.9623564804567536 1.1035796220799832 1.0302230527727365 1.0 12.717178602085436 -6.252926238306039 0.5267084370662171 0.9978568914744266 1.5430465698126616 0.8689204995106242 0.06644481425365692 0.40120976275350534 0.21984637049707856 0.05149848274443173 0.11198122955617505 5.58565054809265e-07 6.252926238306039 0.5451896783382351 TMS(ph)QGEITK ddPTM_PC-9_AZD4547_30min_R2 1 TMSQGEITK 9 0 H3BV44;H3BRD5;B2RTY4-5;B2RTY4-2;B2RTY4;B2RTY4-4 H3BV44 MYO9A Unconventional myosin-IXa 1 T(0.038)MS(0.962)QGEITK 66.267 0.043066 6602500.0 44059.0 47745.0 69953.0 84624.0 90481.0 66602.0 57301.0 72400.0 60819.0 73511.0 True False 58068.84551586931 63177.637545637146 69025.37751352185 65115.24422776695 77919.2749657468 62437.36641135748 62400.67799325428 61212.243586490156 64033.768175550635 70937.4022650069 0.8185927826753027 0.8906110955348924 0.973046309979859 0.9179254123869716 1.0984230106799953 0.8801755409382612 0.8796583466665265 0.8629050632248185 0.9026799139942316 1.0 16.114258879148565 -5.171219847015674 0.006385428361457929 1.8213678906337134 1.0644372969216575e-07 0.06345727944856694 0.07428126121469987 69113.98687338491 78.48289435375243 10743.057284742534 11654.424106221382 6.7418665691791855e-06 5.171219847015674 -1.8213677841899838 TMS(ph)QGEITK ddPTM_PC-9_Lapatinib_30min_R1 1 TMSQGEITK 9 0 H3BV44;H3BRD5;B2RTY4-5;B2RTY4-2;B2RTY4;B2RTY4-4 H3BV44 MYO9A Unconventional myosin-IXa 1 T(0.001)MS(0.998)QGEIT(0.001)K 72.321 0.028709 4856600.0 55996.0 56899.0 58781.0 38591.0 41303.0 38780.0 42404.0 38333.0 39253.0 37474.0 True False 55197.48677159124 56767.25386136416 53948.25308122167 41429.11087580213 38873.63874482231 37121.46980059532 44599.4716356345 40114.09112149658 34831.913787585276 43951.330969033734 1.25587747980786 1.2915935105892467 1.2274543658127521 0.942613339855199 0.8844701147323855 0.8446039967879369 1.014746781321763 0.9126934324186744 0.7925110120584604 1.0 15.423619234414147 -5.754838178461182 3.78663140958577 0.9060908099986346 1.2714168493601483 0.8677194188547924 0.062058287664960736 0.0705852027390757 2.1953229717513225 0.01764689679784178 0.029958546788138515 1.758578752167064e-06 5.754838178461182 0.36532603936151375 TMS(ph)T(ph)ELFS(ph)STR ddPTM_PC-9_AZD4547_30min_R2 1 TMSTELFSSTR 11 0 D6RD20 D6RD20 CDC25C 3 T(0.413)MS(0.668)T(0.919)ELFS(0.692)S(0.297)T(0.011)R 66.538 0.033158999999999994 0.0 10517.0 6803.4 11796.0 16660.0 12047.0 9777.8 8974.4 12349.0 10108.0 12008.0 True False 13861.187232810502 9002.46600226176 11639.577332630519 12819.294394434157 10374.48199635669 9166.39262029626 9773.104214283532 10440.745801789586 10642.288244109017 11587.603574950748 1.196208270601751 0.7769049004854331 1.0044852895893093 1.106293834744743 0.895308674416814 0.7910516234876649 0.8434103005914294 0.9010271825625483 0.9184201181264738 1.0 13.500294613882454 -6.486902371668792 21.532281868539247 0.877362569134001 1.0021670691977629 0.2325247287473623 0.111861879822042 173.5066436751355 103845.04546846428 0.034111444733538616 0.038647279551968665 3.25909956524388e-07 6.486902371668792 0.12480450006376187 TMS(ph)VQQPDPPAANPKPER ddPTM_PC-9_AZD4547_30min_R2 1 TMSVQQPDPPAANPKPER 18 1 Q9BZ71;Q9BZ71-3;Q9BZ71-2 Q9BZ71 PITPNM3 Membrane-associated phosphatidylinositol transfer protein 3 1 T(0.237)MS(0.763)VQQPDPPAANPKPER 72.86399999999999 0.011595000000000001 13459000.0 16603.0 16619.0 22533.0 30262.0 29115.0 29159.0 23096.0 34060.0 23161.0 25374.0 True False 21882.408636146498 21990.76674774205 22234.197697199343 23285.563443239276 25072.884811482098 27335.683120458452 25151.499257119438 28796.809620937198 24385.243175881365 24485.66398324451 0.8936824686935418 0.8981078382350705 0.908049612720903 0.9509876252150458 1.0239822301179753 1.1163954197510921 1.027192861681454 1.176068153211724 0.9958987917406747 1.0 14.579649698011723 -6.2144948370132616 1.9566672103163905 1.0723165032597188 0.8992540314123366 0.6623005520622711 0.05145859659478873 0.18187018678885603 1.368827917842851 0.016463509401412176 0.022265127164397967 6.102463113416855e-07 6.2144948370132616 -0.17306247184738222 TMS(ph)VQQPDPPAANPKPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TMSVQQPDPPAANPKPER 18 1 Q9BZ71;Q9BZ71-3;Q9BZ71-2 Q9BZ71 PITPNM3 Membrane-associated phosphatidylinositol transfer protein 3 1 T(0.221)MS(0.779)VQQPDPPAANPKPER;T(0.244)MS(0.756)VQQPDPPAANPKPER 98.887 0.0010405 16101400.0 36266.0 38639.0 31303.0 35929.0 48287.0 41977.0 40015.0 44480.0 38706.0 33693.0 True False 42405.11751384991 42474.82456374505 32049.382237288595 33916.014613389634 38825.50898112984 39775.652223714824 36224.489516487825 43312.44713045566 39272.00202544217 39801.27418635873 1.0654211047440187 1.0671724820885922 0.805235080847563 0.8521338903520286 0.9754840711716883 0.9993562527037718 0.910133915484123 1.0882176014681542 0.9867021302273292 1.0 15.280526997075052 -7.752548066863676 24.99775517359676 1.028094906476836 0.9509304709538332 0.13462500734188254 0.08266677542909781 386.93214400961995 1087860.1267766915 0.04283932183386993 0.024262063659336724 1.767876541788735e-08 7.752548066863676 -0.0771644355230029 TMS(ph)VQQPDPPAANPKPER ddPTM_PC-9_Lapatinib_30min_R1 3 TMSVQQPDPPAANPKPER 18 1 Q9BZ71;Q9BZ71-3;Q9BZ71-2 Q9BZ71 PITPNM3 Membrane-associated phosphatidylinositol transfer protein 3 1 T(0.185)MS(0.815)VQQPDPPAANPKPER;T(0.176)MS(0.824)VQQPDPPAANPKPER;T(0.429)MS(0.571)VQQPDPPAANPKPER 90.30799999999999 0.0020594999999999997 24660000.0 66754.0 54679.0 58730.0 50522.0 71802.0 58964.0 61489.0 56551.0 71977.0 61420.0 True False 65802.07571881557 54552.39413496773 53901.446104356 54237.55641645139 67578.74752816345 56442.247171797404 64672.59955201232 59178.56590957535 63870.192308588455 72036.36516299433 0.9134563573540581 0.7572896551836535 0.7482532743343582 0.7529191165285734 0.9381198978495823 0.7835243636195048 0.8977771075161793 0.8215096052622025 0.8866381884215209 1.0 16.13643776660123 -9.414278062440902 0.3112548438459815 1.0439299942692803 0.7945534944813356 0.409564265570209 0.06498296648494895 4.831260441380956 0.7403496669578212 0.3474668639298661 0.07623983734240652 3.852316293491276e-10 9.414278062440902 -0.24937649978794474 TMSS(ph)DDEDCSAK ddPTM_PC-9_Lapatinib_30min_R1 2 TMSSDDEDCSAK 12 0 H0YBW3;Q9NVR2 H0YBW3 INTS10 Integrator complex subunit 10 1 T(0.036)MS(0.072)S(0.892)DDEDCSAK;TMS(0.147)S(0.576)DDEDCS(0.277)AK 115.34 0.00072717 2967200.0 21646.0 25553.0 24625.0 26332.0 32016.0 31443.0 27354.0 27843.0 28901.0 26525.0 True False 21337.324070609757 25493.83359847163 22600.42755524887 28268.543120976956 30132.881825877816 30098.25618721297 28770.25627585006 29136.687425868808 25645.865038977958 31109.81090765915 0.6858712235167127 0.819478899249597 0.726472675206287 0.9086697185297683 0.9685973956999907 0.9674843822275648 0.9247968867842556 0.9365755231477616 0.8243658283587965 1.0 14.925082005427482 -5.81963633186682 5.381287246799064 0.9345899359837312 0.7513813405188806 0.7241980345258326 0.053506674797043005 0.10142147955494846 5.931971680730865 0.014815952474916627 0.022719737924450995 1.5148292003473948e-06 5.81963633186682 -0.18320859546485058 TMTTNSS(ph)DPFLNSGTYHSR ddPTM_PC-9_AZD4547_30min_R2 1 TMTTNSSDPFLNSGTYHSR 19 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8;H0YCI3;P46937-4 P46937-6 YAP1 Transcriptional coactivator YAP1 1 TMTT(0.014)NS(0.212)S(0.773)DPFLNSGTYHSR 97.352 0.00042283 7630500.0 8953.2 8023.3 13776.0 19690.0 15310.0 12238.0 11152.0 15539.0 12444.0 13178.0 True False 11800.13136187116 10616.674820817056 13593.321238921499 15150.774707467503 13184.470769836544 11472.755925380516 12144.506395713363 13137.804600697105 13101.76443507049 12716.642231071019 0.9279282335268884 0.834864630765263 1.0689395039917424 1.191413144457983 1.0367886844864176 0.9021843751606637 0.9550088911080838 1.033118991788339 1.0302848973024097 1.0 13.634430163687847 -5.262665033732216 24.99919170639045 1.0275617709992946 0.8813964276281189 0.38321734803203367 0.07399750736596251 117.65068616201732 2399733.817081916 0.021600667333165437 0.04933249169675944 5.4617896013670116e-06 5.262665033732216 -0.1461653433711757 TNATSPGVNSST(ph)SPQSTDK ddPTM_PC-9_AZD4547_30min_R2 2 TNATSPGVNSSTSPQSTDK 19 0 B7ZM87;O75044 B7ZM87 SRGAP2 SLIT-ROBO Rho GTPase-activating protein 2 1 TNATSPGVNS(0.079)S(0.187)T(0.543)S(0.187)PQS(0.003)T(0.001)DK;TNATSPGVNS(0.001)S(0.002)T(0.988)S(0.009)PQSTDK 184.97 1.9161e-10 17221400.0 46414.0 35293.0 49730.0 60445.0 58508.0 57689.0 55867.0 59904.0 45799.0 54895.0 True False 61172.68652882632 46700.772057768794 49070.54770699523 46510.339115940755 50385.174121593496 54081.697710351116 60839.054771280375 50647.21325697658 48219.84163948839 52973.14275873757 1.1547868097506124 0.8815933815832705 0.9263287989252132 0.8779984855300883 0.9511456465981111 1.0209267355849054 1.1484886794118963 0.9560922878909739 0.9102696032044435 1.0 15.692973482067064 -6.7542296085939375 20.401319677227807 1.0132445832762484 0.9478598362286912 0.057801584133493455 0.09217409545935365 42.96725407573148 121580.0997814882 0.03151075711756569 0.030710936761442466 1.7610447476433966e-07 6.7542296085939375 -0.06538474704755726 TNATSPGVNSST(ph)SPQSTDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TNATSPGVNSSTSPQSTDK 19 0 B7ZM87;O75044 B7ZM87 SRGAP2 SLIT-ROBO Rho GTPase-activating protein 2 1 TNATSPGVNS(0.002)S(0.008)T(0.986)S(0.003)PQSTDK;TNATSPGVNS(0.013)S(0.013)T(0.969)S(0.005)PQSTDK;TNATSPGVNS(0.182)S(0.182)T(0.601)S(0.035)PQSTDK;TNATSPGVNS(0.027)S(0.027)T(0.926)S(0.019)PQSTDK 237.16 2.8448e-43 26677700.0 77368.0 76941.0 68198.0 88141.0 96411.0 76687.0 91654.0 82818.0 75199.0 64415.0 True False 90464.87431234588 84579.19399464548 69824.09896235514 83202.74552697764 77519.95664215449 72665.39872025201 82971.86960250324 80644.11525292452 76298.64311246909 76092.92959114054 1.188873589155104 1.1115250056621948 0.917616121990981 1.0934359601350516 1.0187537404418727 0.9549559875102036 1.090401829030954 1.059810887637501 1.0027034511936113 1.0 16.21547478705374 -5.021431237558162 7.494189299457114 1.0218666846347015 1.1708558512416718 0.5255203175412784 0.05271879559876494 0.11787386848525414 33.52625571765868 0.01308402427525848 0.03896220368771168 9.518505439867146e-06 5.021431237558162 0.14898916660697026 TNATSPGVNSST(ph)SPQSTDK ddPTM_PC-9_Lapatinib_30min_R1 2 TNATSPGVNSSTSPQSTDK 19 0 B7ZM87;O75044 B7ZM87 SRGAP2 SLIT-ROBO Rho GTPase-activating protein 2 1 TNATSPGVNS(0.008)S(0.008)T(0.982)S(0.003)PQSTDK;TNATSPGVNS(0.007)S(0.007)T(0.942)S(0.043)PQSTDK 311.19 1.4746999999999997e-138 16551700.0 35155.0 38316.0 36860.0 34912.0 43050.0 36914.0 37611.0 35996.0 39150.0 30218.0 True False 34653.68325336256 38227.28165612802 33829.51308371467 37479.5449430179 40517.88363955648 35335.274270736896 39558.31354796363 37668.50556985862 34740.514732223375 35441.14103704597 0.977781251939369 1.0786131749022907 0.9545266346913974 1.0575151884596836 1.1432443328278816 0.9970128849350981 1.1161692990249399 1.062846862929284 0.9802312712197883 1.0 15.113137432144073 -4.743871745573261 24.47313700469712 1.0469310641425804 0.9777809758595055 0.10180593425781514 0.05755090276689477 1981.5674338417036 2760291.269630169 0.014085160375348838 0.4135998864880394 1.8035502807950555e-05 4.743871745573261 -0.0691500882830749 TNEGVIEFR ddPTM_PC-9_Lapatinib_30min_R1 1 TNEGVIEFR 9 0 Q13247-3;Q13247;A0A590UJK4;A0A590UK01;A0A590UJP7;A0A590UK80 Q13247-3 SRSF6 Serine/arginine-rich splicing factor 6 0 99.01299999999999 0.019708 4651300.0 32251.0 32735.0 31867.0 32939.0 35367.0 36901.0 31583.0 29308.0 37964.0 36377.0 False True 31791.09482589093 32659.204118732407 29247.01827017729 35361.44394128286 33286.782594197284 35322.83025043242 33218.213203194166 30669.756674114255 33688.09454135701 42664.71598069433 0.7451378520901514 0.7654850939007917 0.6855083316014922 0.8288217354425567 0.7801946369280758 0.8279166856850964 0.7785874683479744 0.7188552875399953 0.7896008157326251 1.0 15.380755823566405 -8.568814558721886 21.385042828584588 1.0000000004472656 0.7677028535482975 0.7373038778709774 0.04158348816141668 2450.972255145209 1141028.2244596162 0.041248021569366654 0.010650193370655854 2.6988915978329908e-09 8.568814558721886 -0.23229714689896808 TNGHS(ph)PSQPR ddPTM_PC-9_AZD4547_30min_R2 1 TNGHSPSQPR 10 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 TNGHS(0.793)PS(0.207)QPR 82.20200000000001 0.0086356 607010.0 1046.1 2342.3 3210.5 3467.3 3307.7 2981.7 3212.1 1161.6 2836.2 2770.6 True False 1378.738039768286 3099.402668827015 3167.9266722965654 2667.9675542509935 2848.482950058025 2795.253827643987 3497.970677337776 982.101410912527 2986.1157417829436 2673.602137305006 0.5156855691168976 1.159260993092718 1.1848908362595187 0.9978925125113446 1.0654101858735416 1.0455010446923136 1.3083362810532964 0.367332669737647 1.1168885976403922 1.0 11.384569076479519 TNGHS(ph)PSQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TNGHSPSQPR 10 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 T(0.001)NGHS(0.985)PS(0.014)QPR;TNGHS(0.937)PS(0.063)QPR 68.033 0.023827 19819400.0 7688.0 10116.7 14208.2 11339.4 17467.1 18390.4 11723.1 14914.6 16127.0 14953.7 True False 8989.426555078531 11121.019117058924 14546.977372898556 10704.090180830812 14044.5471436265 17425.975049551074 10612.603100105913 14523.10755332494 16362.826865713474 17664.687436575925 0.508892477568854 0.6295621791774308 0.8235060725036131 0.6059597838491765 0.7950634390816517 0.9864864641459447 0.6007806896221556 0.822154799255257 0.9263015224279111 1.0 14.10858060159481 -3.6415852570806346 0.1628483483040779 1.0158523807166022 1.4237891111935177e-16 0.5113126584446217 0.11568402841949477 29.691984061264957 0.5819747548718583 0.3995811915636139 6.4954467811720855 0.00022825207951954372 3.6415852570806346 -1.015852380716602 TNGHS(ph)PSQPR ddPTM_PC-9_Lapatinib_30min_R1 3 TNGHSPSQPR 10 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 T(0.008)NGHS(0.961)PS(0.031)QPR;TNGHS(0.919)PS(0.081)QPR;T(0.157)NGHS(0.842)PS(0.001)QPR 129.76 0.00023557 34975830.0 23733.4 22521.100000000002 26467.600000000002 20915.9 27191.5 23435.5 26059.6 21754.800000000003 28516.3 18723.4 True False 23394.957363827496 22468.953776642265 24291.53609589058 22454.125059397 25592.149430545873 22433.218295818766 27408.838577397903 22765.607427801988 25304.49400404855 21959.71474263771 1.0653579811036011 1.0231896925790116 1.106186322572093 1.022514423459214 1.1654135643599828 1.0215623726778966 1.2481418314683295 1.0366986864177945 1.1523143310653534 1.0 14.422571693361828 -6.244939864073421 24.626020633510343 1.1089397676755317 1.0557943804930054 0.09668404870953495 0.07346478654924106 1528.6311584607276 2281527.28596965 0.020115083848756033 0.02588918941974934 5.689317042752591e-07 6.244939864073421 -0.05314538718252626 TNGKEPELLEPIPYEFMA ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TNGKEPELLEPIPYEFMA 18 1 P46778 P46778 RPL21 60S ribosomal protein L21 0 65.563 0.043983999999999995 0.0 4719.1 5739.7 4086.0 6609.3 5023.2 5728.5 4382.0 4027.0 5436.1 5063.0 False True 5517.950423526421 6309.499483644181 4183.425736241294 6239.002348639712 4038.940019342916 5428.087375552101 3966.9052370673385 3921.295516959191 5515.592678409191 5980.881821314049 0.9225981365928547 1.0549446841031096 0.699466376568892 1.0431576036840922 0.6753084478194099 0.9075730866655889 0.6632642736612001 0.6556383546962729 0.9222039229655551 1.0 12.546142495748608 -5.252947170254098 24.9725585930149 0.8087420693258254 0.9887714152717909 0.18222725342650292 0.140456209833791 930.2411681637376 2735491.4442156944 0.03426760659356265 0.08757627878879748 5.58538133967655e-06 5.252947170254098 0.18002934594596554 TNIIPVLEDAR ddPTM_PC-9_Lapatinib_30min_R1 2 TNIIPVLEDAR 11 0 A6NHQ2 A6NHQ2 FBLL1 rRNA/tRNA 2-O-methyltransferase fibrillarin-like protein 1 0 ; 130.01 0.0010638 6597000.0 42444.0 38171.0 41415.0 35748.0 34365.0 44002.0 39570.0 40051.0 38190.0 34784.0 False True 41838.74077672366 38082.61739471927 38010.01856652315 38377.027171832146 32343.71826418949 42120.13703367189 41618.74098250302 41911.91567336391 33888.640041471524 40796.36805323339 1.0255506255392668 0.9334805820220795 0.9317010405662961 0.9406971503383744 0.7928087672408876 1.0324482066322955 1.0201579936771958 1.0273442875766512 0.8306778681193318 1.0 15.316153099765302 TNILQYASTRPPT(ph)LSPIPHIPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TNILQYASTRPPTLSPIPHIPR 22 1 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 T(0.004)NILQY(0.01)AS(0.011)T(0.009)RPPT(0.692)LS(0.273)PIPHIPR 50.028999999999996 0.027855 11429000.0 6816.4 5841.7 8571.7 9295.0 8780.4 7976.0 7950.5 11035.0 5294.7 5053.9 True False 7970.281889963228 6421.625369549664 8776.081836353282 8774.231284796588 7059.9436506287875 7557.724519054469 7197.371083364646 10745.342942548961 5372.124970911706 5970.132063349613 1.335026060628114 1.075625346543295 1.4699979402849854 1.46968797200672 1.1825439664843398 1.2659225020248746 1.2055631277487144 1.799850125345495 0.8998335235984063 1.0 12.543547129892914 TNILQYASTRPPTLS(ph)PIPHIPR ddPTM_PC-9_AZD4547_30min_R2 2 TNILQYASTRPPTLSPIPHIPR 22 1 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 TNILQYAS(0.005)T(0.005)RPPT(0.052)LS(0.938)PIPHIPR;TNILQY(0.002)AS(0.015)T(0.015)RPPT(0.226)LS(0.742)PIPHIPR 69.03 0.00089971 84626000.0 122608.0 127548.0 167559.0 151513.0 164432.0 195199.0 158144.0 208088.0 167514.0 179521.0 True False 161594.79359517278 168775.3966629162 165337.05817889445 116584.01870251523 141603.4551029237 182993.17567236064 172218.5096344776 175932.78098654086 176368.44805339092 173236.02443194002 0.9328013276976304 0.9742511536867074 0.9544034430543696 0.6729779160241471 0.8174018975975523 1.056322876678886 0.9941264249119145 1.0155669501389437 1.0180818258311022 1.0 17.402379444138397 -6.7644081472499495 24.99982695116866 1.016374235765838 0.8698410913202137 0.44868134200425824 0.08116883267573981 84.71775340520274 713397.8339158574 0.031368394170543414 0.028868080027479898 1.7202511337701208e-07 6.7644081472499495 -0.14653314444562437 TNILQYASTRPPTLS(ph)PIPHIPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TNILQYASTRPPTLSPIPHIPR 22 1 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 T(0.001)NILQY(0.027)AS(0.096)T(0.096)RPPT(0.193)LS(0.586)PIPHIPR;TNILQYAST(0.008)RPPT(0.181)LS(0.811)PIPHIPR 66.137 0.0011811 58421000.0 78565.0 103011.0 109566.0 97763.0 111751.0 87690.0 121361.0 108933.0 94685.0 77495.0 True False 91864.50277051846 113237.2513040176 112178.46897136891 92285.65606192252 89854.19376126578 83091.38203057763 109864.80750244838 106073.62417405398 96069.5889985786 91544.23004991752 1.0034985571502026 1.2369676520548727 1.2254018512166185 1.0080991015119218 0.981538582085073 0.9076637815979152 1.2001281505403558 1.1587144718592732 1.0494335792238734 1.0 16.482181336673094 -5.768020769310837 24.997440550230902 1.0485324130345208 1.1634571868570145 0.20797146401363298 0.09913237455413923 249.4823948366525 947587.8163225984 0.02980561759760694 0.04538896879748524 1.7060008007959153e-06 5.768020769310837 0.11492477382249366 TNILQYASTRPPTLS(ph)PIPHIPR ddPTM_PC-9_Lapatinib_30min_R1 1 TNILQYASTRPPTLSPIPHIPR 22 1 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 TNILQY(0.001)AS(0.005)T(0.005)RPPT(0.022)LS(0.966)PIPHIPR 62.847 0.0019749000000000004 12378000.0 30213.0 29898.0 35020.0 32592.0 37849.0 38594.0 32564.0 39023.0 37651.0 29424.0 True False 29782.157079614386 29828.77301792765 32140.790781109255 34988.9244037248 35622.79623399707 36943.42458700815 34250.004583124275 40836.15104046541 33410.34789739315 34509.89919498447 0.8630033055542162 0.8643541045829205 0.9313498888973999 1.0138808057952817 1.032248631985988 1.0705167342933692 0.9924689837431351 1.183317018972932 0.9681380901352755 1.0 15.07472263914993 -5.645169234203166 1.5361027447177413 1.0506343777860085 0.8547572431309663 0.6219763353916674 0.05571360599774909 0.24743847093322666 1.1518314089128323 0.016758269917458216 0.044094886400436704 2.263762001628339e-06 5.645169234203166 -0.1958771346550422 TNKPS(ph)TPTTATR ddPTM_PC-9_Lapatinib_30min_R1 1 TNKPSTPTTATR 12 1 A0A2R8Y7K2;A0A2R8Y5N9;A0A2R8Y481;A0A2R8YFW8;A0A2R8YGN6;A0A2R8YCL5;A0A2R8Y4I8;A0A2U3TZR0;Q9UBP0-4;Q9UBP0-3;Q9UBP0-2;Q9UBP0;A0A2R8YEA0 A0A2R8Y7K2 SPAST Spastin 1 T(0.016)NKPS(0.578)T(0.399)PT(0.007)TATR 53.981 0.041069999999999995 6048700.0 19695.0 20126.0 19440.0 15944.0 14406.0 13554.0 13837.0 13859.0 15432.0 12121.0 True False 19414.14568837935 20079.39948353776 17841.718240570088 17116.57494762481 13558.66740328573 12974.327015917199 14553.41215503902 14502.939734766933 13693.885653835778 14216.098699782726 1.3656451111074566 1.4124409169897396 1.2550361823840444 1.2040275823272395 0.9537544504733184 0.9126503191846504 1.023727568468658 1.0201771977700598 0.9632660790435473 1.0 13.795237982432221 -5.921017832349056 1.7229005086340454 0.9775829711033365 1.3781126572504188 0.9291229479357401 0.046049774895315525 0.08838546210341451 0.5330507960711499 0.015763637624334068 0.02819590893385585 1.199450052118053e-06 5.921017832349056 0.4005296861470823 TNKS(ph)PEAKPLPGK ddPTM_PC-9_Lapatinib_30min_R1 1 TNKSPEAKPLPGK 13 2 P46087-2;P46087;P46087-4;P46087-3;F5H359;F5GWB7;F5H709;F5H5X6 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 T(0.209)NKS(0.791)PEAKPLPGK 82.59 0.030001 0.0 18666.0 39462.0 39931.0 40258.0 44191.0 42233.0 47538.0 50435.0 30985.0 35305.0 True False 18399.81941707483 39370.62816353806 36648.02731811747 43218.7076167511 41591.7722628488 40426.79303993147 49999.285034779605 52778.39422201964 27495.14301348508 41407.42220904453 0.44436041741945953 0.9508108948385204 0.8850593773527038 1.0437430129932341 1.004452101675723 0.9763175508931135 1.2074957185781627 1.2746119271943321 0.6640148443599413 1.0 15.337601771052547 -4.571481154717019 1.7057908211872443 1.0283622968903758 1.6292833107432114e-20 0.523591580367201 0.15860995134084527 1.3935640918829042 2.606792755137619 0.04307419433013164 2.7805049133645823 2.6823710008530258e-05 4.571481154717019 -1.0283622968903758 TNLQPLESTQS(ph)QDF ddPTM_PC-9_AZD4547_30min_R2 2 TNLQPLESTQSQDF 14 0 Q9Y248 Q9Y248 GINS2 DNA replication complex GINS protein PSF2 1 TNLQPLEST(0.001)QS(0.999)QDF;TNLQPLESTQS(1)QDF 139.21 5.498e-05 7306800.0 62625.0 56580.0 78556.0 97972.0 84662.0 84229.0 70838.0 85488.0 70444.0 77332.0 True False 82538.44731907932 74868.37851779569 77514.2961124215 75386.06905231102 72908.1426724951 78962.14731482882 77142.44476861034 72277.79391881036 74167.52602572365 74624.630218029 1.1060483258399902 1.003266325059897 1.0387226829258631 1.0102035860285987 0.9769983778744515 1.0581244702201809 1.0337397256539176 0.9685514515467355 0.9938746203368803 1.0 16.187364257063408 TNLQPLESTQS(ph)QDF ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TNLQPLESTQSQDF 14 0 Q9Y248 Q9Y248 GINS2 DNA replication complex GINS protein PSF2 1 TNLQPLES(0.012)T(0.1)QS(0.887)QDF;TNLQPLES(0.001)T(0.017)QS(0.981)QDF;TNLQPLESTQS(1)QDF 120.21 9.005200000000001e-05 7144000.0 82209.0 82351.3 88270.1 93301.7 107553.0 87615.6 93208.4 82018.0 78851.8 68423.7 True False 96125.35999823756 90526.59282321864 90374.79395021858 88074.30823719266 86478.76172567047 83020.8836975513 84379.02558162216 79865.1144052541 80004.85840205023 80828.37516828883 1.1892526578457085 1.1199853100441228 1.1181072706466462 1.0896459078116743 1.0699059772711903 1.0271254806829602 1.0439282666011869 0.9880826410152479 0.9898115387755353 1.0 16.302574226093647 -5.5435492756934295 0.3910941700418712 0.9832354049152647 1.2432724784107618 0.9347796267227532 0.016064171377373825 0.7443399782639533 0.13961792253481756 0.01476426537779597 0.08611020455226315 2.8605577791027506e-06 5.5435492756934295 0.2600370734954971 TNLQPLESTQS(ph)QDF ddPTM_PC-9_Lapatinib_30min_R1 2 TNLQPLESTQSQDF 14 0 Q9Y248 Q9Y248 GINS2 DNA replication complex GINS protein PSF2 1 TNLQPLESTQS(1)QDF;TNLQPLESTQS(1)QDF 146.84 0.00019891 8117200.0 88424.0 73028.0 95860.0 79246.0 82794.0 79102.0 70325.0 76228.0 85450.0 70815.0 True False 87163.05754502436 72858.90815282705 87978.76083030085 85074.01519690626 77924.21969926692 75718.99185576824 73966.0843971322 79769.83116399565 75825.7211716088 83055.27839494383 1.0494583755477558 0.877233928545383 1.0592795850005452 1.0243059422709169 0.9382211607156653 0.9116698338630552 0.8905645231289123 0.960442643809762 0.9129548733921872 1.0 16.341784237950506 -6.357142204685935 6.176944028694825 0.9295495464705207 0.9974695085754471 0.26019032631133776 0.05455596078407495 0.33164203462658287 17.772023583089307 0.016717013404668468 0.01898603616799016 4.393977161992857e-07 6.357142204685935 0.06791996210492646 TNLQYRSLPRPS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 TNLQYRSLPRPSK 13 2 Q8IVL1-4;Q8IVL1-11;A0A0A0MTL4;A0A0A0MTE8;Q8IVL1-8;Q8IVL1-9;Q8IVL1-10;Q8IVL1-13;Q8IVL1-12;Q8IVL1-3;Q8IVL1-2;Q8IVL1;Q8IVL1-5;E9PNV5 Q8IVL1-4 NAV2 Neuron navigator 2 1 T(0.001)NLQY(0.001)RS(0.005)LPRPS(0.994)K 44.294 0.045048000000000005 23011000.0 153220.0 111570.0 144630.0 126200.0 173000.0 208680.0 182850.0 222270.0 219610.0 213940.0 True False 151035.05470289337 111311.66651984022 132739.0796879448 135481.16899085868 162824.4801310863 199755.2428568393 192317.07830807887 232597.47563652837 194875.20920417793 250919.24394286887 0.6019269480075515 0.44361550262436017 0.5290111575426546 0.5399393321211586 0.6489118872371518 0.7960937539821419 0.7664500948036773 0.926981414344959 0.7766451314852062 1.0 17.93686359514917 -6.773852549677652 0.9008519639443352 0.8964214548729605 0.5009989468936413 0.8387769734164603 0.06882101036700904 0.2066434532680317 0.36293975648444166 0.04041067256027523 0.03697912449278604 1.6832454543686366e-07 6.773852549677652 -0.3954225079793192 TNNNQILEVKS(ph)PIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TNNNQILEVKSPIK 14 1 A0A0D9SF09;B1APT5;P42568-2;P42568 A0A0D9SF09 MLLT3 Protein AF-9 1 TNNNQILEVKS(1)PIK 106.28 0.005492 0.0 22491.0 21869.0 16641.0 23948.0 26215.0 19320.0 21297.0 22408.0 21320.0 18605.0 True False 26298.28208250148 24040.009792814013 17037.784551343935 22606.271200463547 21078.358935952092 18306.825189083793 19279.593983072362 21819.813743238523 21631.76466652268 21977.939222901037 1.1965763402921161 1.0938245642141142 0.7752221160749477 1.0285892126277147 0.9590689428237393 0.8329636825097806 0.8772248292953237 0.9928052635845973 0.9842489983766246 1.0 14.423768496851933 -5.043693000719047 6.863838439168401 0.9298610742361567 1.1730281354195855 0.5685349149527652 0.07688491054732063 0.12971069969399265 16.955405680281043 0.019553193312964363 0.05517646317567214 9.042884821053938e-06 5.043693000719047 0.2431670611834288 TNNNQILEVKS(ph)PIK ddPTM_PC-9_Lapatinib_30min_R1 1 TNNNQILEVKSPIK 14 1 A0A0D9SF09;B1APT5;P42568-2;P42568 A0A0D9SF09 MLLT3 Protein AF-9 1 T(0.006)NNNQILEVKS(0.994)PIK 52.365 0.042658 16292000.0 55730.0 66515.0 69263.0 72467.0 76360.0 75404.0 74931.0 79391.0 64694.0 63684.0 True False 54935.27998036966 66360.9886041693 63568.463502911865 77796.46492282522 71868.65492953623 72179.14669530911 78810.56053980114 83079.79569109468 57407.48046197849 74691.69454640403 0.7354938231618213 0.8884654312259701 0.8510780735255432 1.0415678127973422 0.9622041026915795 0.9663610811569694 1.0551448995555746 1.1123029969480653 0.7685925565166111 1.0 16.188660208870765 -4.726064188465062 0.8817502165718812 0.9931879918686621 0.5902931735286144 0.40444450793796205 0.09124015293810947 2.4043984670701755 1.361731255774517 0.03167029761766087 0.9630069688402505 1.8790390754255936e-05 4.726064188465062 -0.4028948183400477 TNPPTQKPPS(ph)PPMSGR ddPTM_PC-9_AZD4547_30min_R2 5 TNPPTQKPPSPPMSGR 16 1 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 TNPPTQKPPS(0.999)PPMS(0.001)GR;TNPPTQKPPS(1)PPMSGR;TNPPT(0.041)QKPPS(0.955)PPMS(0.004)GR;TNPPT(0.069)QKPPS(0.923)PPMS(0.008)GR;TNPPTQKPPS(0.999)PPMS(0.001)GR 151.39 4.7041000000000006e-05 622844500.0 1553950.9 1221158.3 1037505.2 1642187.7 1624102.0 1578100.8 1349533.0 1590148.0 1491648.5 1708150.8 True False 2048074.9620133475 1615873.8394229023 1023747.2031541456 1263606.6973120486 1398623.4713411548 1479421.9075051295 1469638.822608166 1344427.164565886 1570493.9944492325 1648348.9604126366 1.2425008364130894 0.980298394472488 0.6210743160221774 0.7665893131001373 0.8484996229142115 0.8975174207861792 0.8915823396037853 0.81562047652175 0.9527679102949691 1.0 20.652590267041163 -4.87173586461631 3.7427952678342513 0.8406880451729499 1.2501930370954195 0.5850819320590329 0.10019643033324857 0.16193615006302753 3.81487365841168 0.025755782298120443 0.1538145170075297 1.3435818713900408e-05 4.87173586461631 0.4095049919224696 TNPPTQKPPS(ph)PPMSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TNPPTQKPPSPPMSGR 16 1 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 TNPPTQKPPS(1)PPMSGR;TNPPTQKPPS(0.999)PPMS(0.001)GR 103.97 0.0028118 54312000.0 56503.0 60882.0 52396.0 69376.0 76434.0 60374.0 68507.0 59230.0 56276.0 58037.0 True False 66067.84191488063 66925.96260487918 53645.319352936574 65489.08764002675 61457.306386060016 57207.88115764724 62017.521012271136 57675.275259372494 57098.93003626781 68558.64867936075 0.963668963544931 0.9761855563676961 0.7824734061464406 0.955227223720673 0.8964194535613921 0.834437117119979 0.9045907731104568 0.8412545516921099 0.8328479504214202 1.0 16.065051053136415 -5.192411535251392 24.99998439438132 0.8776310817158978 0.9699276708051693 0.2570322224019337 0.06033487747642723 211.96687354534416 76767.05819037213 0.014407739767370049 0.038119294284052474 6.420789981463913e-06 5.192411535251392 0.09229658908927152 TNPPTQKPPS(ph)PPMSGR ddPTM_PC-9_Lapatinib_30min_R1 3 TNPPTQKPPSPPMSGR 16 1 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 TNPPTQKPPS(1)PPMSGR;TNPPTQKPPS(1)PPMSGR;TNPPT(0.016)QKPPS(0.977)PPMS(0.007)GR 118.05 0.00028713 64006000.0 70922.0 61134.0 53557.7 59899.0 62781.0 57074.2 49856.1 53194.9 57641.7 46471.7 True False 69910.63927449821 60992.44797906179 49154.392644700594 64304.172277206424 59088.345012195 54633.26951245839 52437.404910229154 55666.52925152997 51149.48475198975 54504.271425352104 1.2826634949197762 1.1190397813609114 0.9018447794870794 1.1798006026972776 1.0841048502615276 1.0023667518844457 0.9620788158235692 1.0213241603966705 0.9384491052603648 1.0 15.734081675910549 -4.891685068418998 3.4916590420768236 1.0178694614007038 1.287738821252894 0.5588701761985928 0.07414362714098117 0.19618207532465465 4.133241524088673 0.019287060293285745 0.11785253360982757 1.2832608105911451e-05 4.891685068418998 0.2698693598521902 TNPS(ph)PTNPFSSDLQK ddPTM_PC-9_AZD4547_30min_R2 1 TNPSPTNPFSSDLQK 15 0 G3V3Z8;P49757-3;P49757;P49757-9;P49757-8;P49757-7;P49757-6;P49757-5;P49757-4;P49757-2 G3V3Z8 NUMB Protein numb homolog 1 T(0.012)NPS(0.941)PT(0.046)NPFSSDLQK 178.99 3.3315e-05 19868000.0 142150.0 152590.0 189230.0 230730.0 219530.0 196730.0 175980.0 241940.0 209080.0 208960.0 True False 187350.743096321 201911.7334399154 186720.6865593146 177538.76324296463 189052.04886363237 184428.44200033543 191641.8790815676 204553.73222811325 220131.54195472025 201644.37400247346 0.9291146555570298 1.001325895843931 0.9259900628669373 0.8804548310422331 0.9375518151640242 0.9146223043052674 0.9503953682298959 1.0144281646340607 1.0916820419300168 1.0 17.621453628695555 -7.810477170884922 3.068246603664857 1.0477500947605158 0.9325069584826002 0.6450876163062274 0.034990139700394864 0.15747667874248672 2.972640563074351 0.022276982987370332 0.009887093306159563 1.5471158274702212e-08 7.810477170884922 -0.1152431362779156 TNPS(ph)PTNPFSSDLQK ddPTM_PC-9_Lapatinib_30min_R1 1 TNPSPTNPFSSDLQK 15 0 G3V3Z8;P49757-3;P49757;P49757-9;P49757-8;P49757-7;P49757-6;P49757-5;P49757-4;P49757-2 G3V3Z8 NUMB Protein numb homolog 1 T(0.002)NPS(0.499)PT(0.499)NPFSSDLQK 169.64 0.00017166 17941000.0 134230.0 146990.0 163770.0 148120.0 164780.0 171720.0 150550.0 159220.0 175700.0 131610.0 True False 132315.85558523278 146649.65368603868 150305.46277048148 159013.2389138353 155087.96436994456 164375.93589887136 158344.7423531925 166617.94246118737 155910.81579697668 154358.61314069835 0.8571977481076904 0.9500581192211611 0.9737419876497438 1.030154622916275 1.004725043937661 1.0648964288701026 1.0258238211097477 1.0794210900904804 1.0100558214711575 1.0 17.235926461365743 -4.147104969507396 0.6994917046207149 1.0392730334151201 0.5328862315943299 0.8223195346167673 0.02521865146003296 2.3565031377979655 0.4617812343936173 0.009637453290714802 1.1578652856383331 7.1268075349793e-05 4.147104969507396 -0.5063868018207902 TNPSPT(ph)NPFSSDLQK ddPTM_PC-9_AZD4547_30min_R2 2 TNPSPTNPFSSDLQK 15 0 G3V3Z8;P49757-3;P49757;P49757-9;P49757-8;P49757-7;P49757-6;P49757-5;P49757-4;P49757-2 G3V3Z8 NUMB Protein numb homolog 1 TNPS(0.012)PT(0.988)NPFSSDLQK;TNPS(0.095)PT(0.905)NPFSSDLQK 176.94 0.00012085 29360000.0 165437.0 180300.0 223870.0 277762.0 265354.0 246988.0 214327.0 270022.0 223483.0 244878.0 True False 218042.5246966307 238578.4490413315 220901.3375259403 213728.2622801212 228514.1774434495 231543.8013154021 233401.68779358504 228296.30438827677 235295.85513041305 236304.89575506208 0.9227169162108222 1.009621270346536 0.93481490013187 0.9044597302870004 0.9670310753117535 0.9798519009754456 0.9877141438301544 0.9661090755602182 0.995729920781265 1.0 17.850289993754423 -6.513813518457705 14.688102085337118 0.9827199181720315 0.945672815593341 0.3582099725649659 0.02685096008901253 2.6305952739228506 4261.487423467096 0.008845421757191057 0.009375750817316252 3.0632784913199494e-07 6.513813518457705 -0.03704710257869048 TNPSPT(ph)NPFSSDLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TNPSPTNPFSSDLQK 15 0 G3V3Z8;P49757-3;P49757;P49757-9;P49757-8;P49757-7;P49757-6;P49757-5;P49757-4;P49757-2 G3V3Z8 NUMB Protein numb homolog 1 T(0.024)NPS(0.24)PT(0.736)NPFS(0.001)SDLQK;TNPS(0.041)PT(0.959)NPFSSDLQK;TNPS(0.058)PT(0.906)NPFS(0.028)S(0.007)DLQK 208.85 1.0263e-12 32876000.0 129436.0 128637.0 133065.0 155161.0 189707.0 150831.0 169468.0 158798.0 151486.0 138217.0 True False 151346.9583224697 141407.231227684 136237.774251823 146467.83220874937 152535.27517309441 142921.15683719984 153414.76419792997 154629.72076038862 153701.196166644 163274.64797482974 0.9269470808830113 0.8660697357588742 0.8344086233940328 0.8970641433036727 0.934225105152939 0.8753419995689253 0.9396116672171925 0.9470528503863391 0.941365962646806 1.0 17.316941272192494 -7.9182198483235515 0.46997339883655054 0.9992034019614522 0.8748327159152973 0.6123877981897954 0.028417857904333318 0.6327849223706382 0.3534046667926852 0.03199523811945056 0.021611134960292003 1.2072025709542205e-08 7.9182198483235515 -0.12437068604615487 TNPSPT(ph)NPFSSDLQK ddPTM_PC-9_Lapatinib_30min_R1 2 TNPSPTNPFSSDLQK 15 0 G3V3Z8;P49757-3;P49757;P49757-9;P49757-8;P49757-7;P49757-6;P49757-5;P49757-4;P49757-2 G3V3Z8 NUMB Protein numb homolog 1 TNPS(0.022)PT(0.97)NPFS(0.006)S(0.001)DLQK;TNPS(0.048)PT(0.95)NPFS(0.002)SDLQK 138.02 6.4818e-05 20334200.0 82498.0 85231.0 87717.0 81311.0 96559.0 91992.0 86384.0 89026.0 105341.0 73048.0 True False 81321.56339171977 85033.65285607695 80505.24685741172 87290.88218554451 90879.58946229808 88057.7166038258 90856.54083984175 93162.47296539144 93476.387290093 85674.24946965811 0.9491949319091513 0.9925228803573234 0.939666788512959 1.0188695287778264 1.060757345700279 1.0278201110476235 1.060488319445611 1.0874034326776951 1.091067477903008 1.0 16.38657402793796 -5.9785017722294365 3.6225304880314275 1.0573579167519176 0.9639100318347544 0.6874423513380887 0.028232268952807532 0.12971770632944657 3.66906463871174 0.008396484537983372 0.012407341044111092 1.0507471670632957e-06 5.9785017722294365 -0.09344788491716316 TNPSPTNPFS(ph)SDLQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TNPSPTNPFSSDLQK 15 0 G3V3Z8;P49757-3;P49757;P49757-9;P49757-8;P49757-7;P49757-6;P49757-5;P49757-4;P49757-2 G3V3Z8 NUMB Protein numb homolog 1 TNPS(0.011)PT(0.29)NPFS(0.565)S(0.134)DLQK 118.76 0.00010788 12361000.0 20931.0 26722.0 21584.0 25579.0 29550.0 25229.0 28343.0 24690.0 30084.0 17917.0 True False 24474.204893905924 29374.783560454365 22098.644417775842 24145.89155823689 23759.8896264499 23905.946826883795 25658.145854449947 24041.91366121739 30523.921586663608 21165.210269106054 1.156341211957146 1.387880544864299 1.044102285628236 1.1408292783881107 1.1225917117927806 1.129492526789506 1.2122792794504875 1.135916598773901 1.4421742660982708 1.0 14.36940720095748 -12.678659842432753 13.67126524498065 0.6240209130257006 1.1802198679108729 0.0 0.1318168890056093 0.0 0.0 0.0 0.028759902047384624 2.0957532946449708e-13 12.678659842432753 0.5561989548851722 TNQELQEINR ddPTM_PC-9_AZD4547_30min_R2 1 TNQELQEINR 10 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YN28;H0YNP5;H0YL33;H0YMM1;H0YNA0;H0YN52;H0YLE2 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 185.96 0.0013814 41328000.0 88450.0 91782.0 144420.0 143520.0 149360.0 135020.0 111740.0 166920.0 134890.0 140670.0 False True 116575.26012570994 121448.73660516633 142504.8964376484 110433.68136189609 128623.94214126607 126577.17805563609 121684.64353093735 141126.34944001297 142020.0100166072 135745.18611661583 0.8587800677186637 0.8946817200635924 1.0497970536887065 0.8135366308093227 0.9475396205267121 0.932461634012541 0.8964195859321349 1.0396416512241862 1.0462250196821035 1.0 17.050541511591106 -7.76510373801956 24.99871961757966 1.0322000370009632 0.9160640569857138 0.4424436943064044 0.05921948213348056 87.74543788285104 598592.0004246475 0.030209649973442377 0.015403261027914677 1.7174980869152875e-08 7.76510373801956 -0.11613598001524938 TNQELQEINR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TNQELQEINR 10 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YN28;H0YNP5;H0YL33;H0YMM1;H0YNA0;H0YN52;H0YLE2 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ;; 146.71 0.00052574 57307600.0 227363.0 254909.0 267317.0 269370.0 334477.0 266362.0 281464.0 273481.0 271403.0 234878.0 False True 265851.0652760562 280214.6808851084 273690.8510853677 254278.07220932265 268938.63291323406 252393.5078164976 254801.69229710722 266302.4135270712 275371.7554309683 277459.5221067748 0.9581616203236617 1.009929948546777 0.9864172222571739 0.916451056639061 0.9692896133863388 0.9096588428468818 0.9183382511523676 0.9597883377907283 0.9924754189009125 1.0 18.081917789988452 -3.707115194645414 12.878944112281784 0.9592056724477387 0.9645689662589626 0.0 0.034843336302187056 0.0 0.0 0.008387579665798017 0.0 0.00019628395734702723 3.707115194645414 0.005363293811223913 TNQELQEINR ddPTM_PC-9_Lapatinib_30min_R1 5 TNQELQEINR 10 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YN28;H0YNP5;H0YL33;H0YMM1;H0YNA0;H0YN52;H0YLE2 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ;;;; 161.67 0.00070384 211947000.0 274325.0 269377.0 286499.0 274165.0 263743.0 251281.0 264023.0 236296.0 291221.0 242680.0 False True 270413.0751949566 268753.27410697355 262944.1581381214 294328.0086876292 248230.15527868847 240534.29739462092 277692.8190655396 247275.17480095843 258420.62428691713 284626.91464922595 0.9500615060533314 0.9442300087403362 0.9238204280932942 1.03408354424373 0.8721246744518423 0.845086269129029 0.975637948392084 0.8687694735605036 0.9079275746125224 1.0 18.11871256565827 -6.298232127247409 24.994779431137736 0.9049065798568497 0.9589027292735288 0.18122352971842015 0.05214423499809861 928.3376659714456 630654.2001718865 0.01570959391702688 0.017813395098953504 5.032315632759847e-07 6.298232127247409 0.05399614941667907 TNQGS(ph)MENLCPGK ddPTM_PC-9_AZD4547_30min_R2 2 TNQGSMENLCPGK 13 0 A0A2R8YGT1;F8W9A8;B7WPL9;Q6PFW1-7;Q6PFW1-4;Q6PFW1-3;Q6PFW1-2;Q6PFW1;H7C398 A0A2R8YGT1 PPIP5K1 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 1 TNQGS(1)MENLCPGK;T(0.003)NQGS(0.997)MENLCPGK 95.98100000000001 0.0029752 9117600.0 33453.0 45496.0 57501.0 58591.0 61665.0 63354.0 66808.0 76950.0 68517.0 60712.0 True False 44090.35813437385 60201.6922772292 56738.49916951404 45083.75017192626 53103.87916538019 59392.46436481106 72753.78257575475 65059.14563508867 72138.66873977211 58586.49135929456 0.7525686743037745 1.0275695109992007 0.9684570257254816 0.7695246655997922 0.9064184922716904 1.0137569768527985 1.241818393417284 1.1104803193640516 1.2313191499618203 1.0 15.83828043164385 -6.979774655560173 3.3504677874765965 1.154593110798987 0.891799084431944 0.6021138643063235 0.09957281486909422 0.16589712332547474 3.905356203404935 0.03791540558252864 0.03134364237728051 1.0476720175964428e-07 6.979774655560173 -0.2627940263670431 TNQGS(ph)MENLCPGK ddPTM_PC-9_Lapatinib_30min_R1 3 TNQGSMENLCPGK 13 0 A0A2R8YGT1;F8W9A8;B7WPL9;Q6PFW1-7;Q6PFW1-4;Q6PFW1-3;Q6PFW1-2;Q6PFW1;H7C398 A0A2R8YGT1 PPIP5K1 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 1 T(0.002)NQGS(0.998)MENLCPGK;T(0.031)NQGS(0.969)MENLCPGK;T(0.002)NQGS(0.998)MENLCPGK 87.566 0.0061955 12935400.0 66990.0 101230.0 85827.0 78862.0 93482.0 95953.0 100211.0 98063.0 80545.0 71942.0 True False 66034.71031553858 100995.6081545529 78770.63536180071 84661.77455592006 87983.57255268331 91849.31386736776 105399.43524381127 102619.36497658197 71473.17392354869 84377.0788433106 0.7826143215761943 1.1969554947748682 0.9335548995252474 1.0033740882774353 1.0427425760504225 1.0885576406115363 1.2491477150985455 1.2161995459353072 0.8470685985263291 1.0 16.36456352148904 -6.547657700819656 2.608338710490835 1.1040837653205329 0.9919764236432209 0.08824193455344742 0.14142672280768712 0.6487155478366999 8.936304355954627 0.04918590130536935 0.051797146861065166 2.833624502179626e-07 6.547657700819656 -0.11210734167731196 TNRPPLSLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TNRPPLSLSR 10 1 F8VUA6;G3V203;H0YHA7;J3QQ67;Q07020-2;Q07020;F8VYV2;A0A075B7A0 F8VUA6 RPL18 60S ribosomal protein L18 0 73.84100000000001 0.034874 3011200.0 20863.0 21244.0 16393.0 13996.0 26422.0 18097.0 21785.0 25051.0 21831.0 16223.0 False True 24394.69383696714 23352.96392329513 16783.871290798703 13211.849495644228 21244.798771914022 17147.961462052244 19721.367090258318 24393.437793728528 22150.23707480565 19164.101478802662 1.2729369996266204 1.2185785985910038 0.8757974543895667 0.6894061540144631 1.1085726505577531 0.8947960060125718 1.0290786193170625 1.2728714581641103 1.1558192331274149 1.0 14.22611873759063 -9.815298529518387 8.347896645429875 1.0000000459811742 1.0483138924111772 0.006712476455190464 0.18099023461572936 0.0 0.0 0.1903383670332482 0.04616383481680381 1.5300353696952905e-10 9.815298529518387 0.04831384643000303 TNRTLS(ph)YRTGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TNRTLSYRTGLK 12 2 M0QX27;M0R2E9;M0R0H5;M0QYR6;M0R1I2;Q03405-2;Q03405-3;Q03405 M0QX27 PLAUR Urokinase plasminogen activator surface receptor 1 T(0.001)NRT(0.03)LS(0.965)Y(0.001)RT(0.003)GLK 52.391000000000005 0.030739 4827800.0 12610.0 11290.0 12236.0 15844.0 16365.0 17698.0 17369.0 18190.0 14519.0 13273.0 True False 14744.623941147294 12410.796586989356 12527.752645288414 14956.312046941053 13158.39572713546 16769.885724451597 15723.682579329668 17712.531773898118 14731.312907750606 15679.28983098982 0.9403885061174662 0.791540734355178 0.7990000044853784 0.9538896345534851 0.8392214104702714 1.0695564598408172 1.0028312984081784 1.1296769155251938 0.9395395497208326 1.0 13.936572595857692 -6.759039980676038 24.99990594959352 1.0348325668522504 0.8620306065554336 0.5937635251086841 0.06749766527276223 42.007616829796426 437688.6041293904 0.02218388033905953 0.02119697188917914 1.7416465319323096e-07 6.759039980676038 -0.17280196029681683 TNS(ph)LSRPGALPPR ddPTM_PC-9_Lapatinib_30min_R1 2 TNSLSRPGALPPR 13 1 Q5JPT2;Q96B97-2;Q96B97;Q96B97-3;Q5VSN0 Q5JPT2 SH3KBP1 SH3 domain-containing kinase-binding protein 1 1 T(0.358)NS(0.6)LS(0.042)RPGALPPR;T(0.019)NS(0.824)LS(0.157)RPGALPPR 78.508 0.018451 6494200.0 98838.0 62627.0 76256.0 79806.0 69441.0 64176.0 44306.0 43864.0 70785.0 43996.0 True False 97428.55199533071 62481.991029291414 69986.5260366725 85675.19946501146 65356.61690625879 61431.34208156283 46599.94788907702 45902.08157340476 62812.447900904976 51600.649979014976 1.8881264486969271 1.2108760462261945 1.356310939205896 1.6603511680541616 1.2665851483041028 1.1905148889896893 0.90308838954603 0.8895640189042634 1.2172801684949632 1.0 15.65510161798084 -6.732085079500756 1.998818175053448 0.9994126521019367 1.4922201249097842 0.5870505622457456 0.19335964687008667 0.23946193577485395 1.970290448174777 0.07591016501340984 0.07113329108426517 1.8531685469631412e-07 6.732085079500756 0.4928074728078474 TNS(ph)MGSATGPLPGTK ddPTM_PC-9_AZD4547_30min_R2 3 TNSMGSATGPLPGTK 15 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 T(0.035)NS(0.964)MGSATGPLPGTK;T(0.168)NS(0.832)MGSATGPLPGTK;T(0.021)NS(0.977)MGS(0.002)ATGPLPGTK 169.58 9.7833e-06 74418200.0 117659.0 98796.0 133116.0 179920.0 167269.0 151615.0 126041.0 145777.0 124495.0 144184.0 True False 155072.11454076774 130729.87493892078 131350.79486355078 138442.22373629 144046.58662310863 142134.49008224966 137258.40482622947 123250.51427220696 131075.55153842003 139136.1620461939 1.1145349437573462 0.9395822984934556 0.944044976746891 0.9950125237055661 1.0352922238525197 1.0215495956763583 0.9865041755331658 0.88582660653876 0.9420667467807706 1.0 17.08613790527616 -7.565758702678723 11.431749491657134 0.9355227479547072 1.0030029656641835 0.2285398624939029 0.05296975422375859 0.9963139111040874 261.461158680515 0.024927031725911774 0.014390894157554861 2.717948962542226e-08 7.565758702678723 0.06748021770947621 TNS(ph)MGSATGPLPGTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TNSMGSATGPLPGTK 15 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 T(0.017)NS(0.443)MGS(0.432)AT(0.108)GPLPGTK;T(0.038)NS(0.962)MGSATGPLPGTK;T(0.001)NS(0.986)MGS(0.012)AT(0.001)GPLPGTK 119.8 8.0583e-05 70148000.0 76502.0 83863.0 90511.0 128183.0 148247.0 167598.0 211305.0 200044.0 170059.0 147079.0 True False 89452.27761662554 92188.36440874118 92669.12550487905 121001.3220848928 119199.06454999413 158808.8658405833 191288.66068427957 194793.0569641381 172545.79115498043 173743.2584232766 0.5148532290024181 0.5306011021397455 0.5333681798410663 0.6964375089024007 0.6860644011844139 0.9140433262376728 1.100984650686466 1.121154620512409 0.9931078346339121 1.0 17.406597473982316 -6.674701175805543 1.2701900871801453 1.072548089715468 0.5393651230012017 0.9373547959129322 0.057723839766845655 0.0989439131576735 0.33571216248403984 0.02792220774297677 0.027281674811552747 2.1149437647173852e-07 6.674701175805543 -0.5331829667142663 TNS(ph)MQQLEQWIK ddPTM_PC-9_AZD4547_30min_R2 2 TNSMQQLEQWIK 12 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;Q9HAU0-3 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 T(0.286)NS(0.714)MQQLEQWIK;T(0.089)NS(0.911)MQQLEQWIK 93.10600000000001 0.019166 7043100.0 32145.0 36074.1 45834.0 63867.0 63951.0 56436.0 38927.6 45428.0 45685.0 48494.0 True False 42366.44134246396 47734.34735752579 45226.21121259643 49143.449885313676 55072.50752461248 52907.04799842909 42392.08098724638 38408.146431589426 48099.81583222403 46796.239820424846 0.905338580728714 1.0200466435059916 0.966449684550442 1.0501580912033954 1.176857536758228 1.1305833161265468 0.9058864804078508 0.82075283353911 1.0278564264308736 1.0 15.514104990333193 -7.284781061264196 24.393231160815738 0.9236866506952439 1.0437188018317833 0.23779709942813954 0.0886454169312762 822.7769811915207 859838.7040697103 0.039542154085506966 0.02668104070363029 5.190616449701017e-08 7.284781061264196 0.12003215113653942 TNS(ph)MQQLEQWIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TNSMQQLEQWIK 12 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;Q9HAU0-3 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 T(0.433)NS(0.567)MQQLEQWIK;T(0.486)NS(0.514)MQQLEQWIK 91.07600000000001 0.0058129 16805400.0 48658.0 51614.0 54755.0 66763.0 78129.0 73434.0 67393.0 66303.0 63454.0 55680.0 True False 56894.83836069344 56737.89681495735 56060.56685949383 63022.48555856635 62820.18330371925 69582.99176683123 61009.04715693277 64562.61650383538 64381.894706826 65774.34323736251 0.8650004783077004 0.8626144180597141 0.8523166344236356 0.9581621412947383 0.9550864396626133 1.0579047747496968 0.9275508375167955 0.9815775167962631 0.9788299135802615 1.0 16.00523731757489 -5.846873135287751 3.4811364910501683 0.9819095308225071 0.8591756366397574 0.7522889904693368 0.031712811007253816 0.11377869899630699 2.7111904155600097 0.00912829941453203 0.014629995035858738 1.4227443339410548e-06 5.846873135287751 -0.12273389418274971 TNS(ph)MQQLEQWIK ddPTM_PC-9_Lapatinib_30min_R1 3 TNSMQQLEQWIK 12 0 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;Q9HAU0-3 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 T(0.058)NS(0.942)MQQLEQWIK;T(0.159)NS(0.841)MQQLEQWIK;T(0.027)NS(0.973)MQQLEQWIK 179.81 9.278300000000001e-26 17018200.0 105678.0 85924.0 86955.2 76766.8 84279.8 84379.0 67567.9 71927.3 80776.0 64768.4 True False 104171.01234102838 85725.04825715466 79806.07911277877 82412.48655853784 79322.62786446203 80770.30686705603 71066.23524972617 75269.30494151847 71678.15627101078 75963.53164153195 1.3713292429926258 1.1285026696979652 1.0505841077713396 1.0848954067517316 1.0442198532682956 1.0632774059032302 0.9355309543148168 0.9908610528629777 0.9435864120859515 1.0 16.2130193593297 -1.5228787452804946 0.610692200386025 0.9914179257503034 25.564831802681354 0.8800742933348733 0.04097441315959859 61.02612655885126 0.45528120920409276 0.019371162788509887 2007.2569564046512 0.029999999999989153 1.5228787452804946 24.57341387693105 TNS(ph)TGGSSGSSVGGGSGK ddPTM_PC-9_AZD4547_30min_R2 2 TNSTGGSSGSSVGGGSGK 18 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 TNS(0.991)T(0.008)GGSSGSSVGGGSGK;T(0.101)NS(0.44)T(0.412)GGS(0.005)S(0.012)GS(0.027)S(0.003)VGGGSGK 195.53 1.6869e-14 144843000.0 26498.0 30243.0 39463.0 59166.0 51205.0 49554.0 46129.0 45970.0 44179.0 40400.0 True False 34923.81280736073 40018.45831590122 38939.69483533388 45526.19280558772 44096.0696126375 46455.38054635611 50234.39163628602 38866.39278551036 46514.211746783956 38985.60829680295 0.8958129508068927 1.026493110258407 0.9988222971636219 1.1677692049586703 1.1310858426762995 1.1916033268657686 1.2885368173261396 0.9969420635844647 1.1931123760507898 1.0 15.250654024788284 -5.389014906144545 1.3635019194101614 1.1477653309581313 0.9202878078708571 0.41453805031320334 0.08887450747484237 0.5287678679938645 1.6647031120281035 0.02728686315910537 0.1216343410650989 4.0830537196318945e-06 5.389014906144545 -0.2274775230872742 TNS(ph)TGGSSGSSVGGGSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TNSTGGSSGSSVGGGSGK 18 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 T(0.476)NS(0.522)T(0.002)GGSSGSSVGGGSGK;TNS(0.499)T(0.499)GGS(0.002)SGSSVGGGSGK 202.86 3.0099999999999996e-16 96101000.0 24261.0 27197.0 23767.0 25108.0 33623.0 24061.0 27246.0 25448.0 23517.0 21271.0 True False 28367.908123407953 29896.938421288716 24333.695416849423 23701.280161234296 27034.814514725058 22799.198803030275 24665.06163604217 24780.016964384788 23860.891635207026 25127.263918856646 1.1289692429313556 1.189820687116383 0.968418029731773 0.9432495411268305 1.075915571310448 0.9073490403354547 0.981605546695929 0.9861804709182336 0.9496016642425092 1.0 14.616965965785944 -5.265772157415812 24.98765682021687 0.9761164153729328 1.1593949725546024 0.7370562508530103 0.04368597729121225 151.787475450362 875381.4134681709 0.010909435310091503 0.02403434765380632 5.422853132705204e-06 5.265772157415812 0.18327855718166963 TNS(ph)TGGSSGSSVGGGSGK ddPTM_PC-9_Lapatinib_30min_R1 4 TNSTGGSSGSSVGGGSGK 18 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 TNS(0.975)T(0.025)GGSSGSSVGGGSGK;T(0.005)NS(0.978)T(0.01)GGSS(0.006)GSSVGGGSGK;T(0.317)NS(0.676)T(0.006)GGS(0.001)SGSSVGGGSGK;T(0.035)NS(0.925)T(0.037)GGS(0.003)SGSSVGGGSGK 225.29 6.9751e-35 254021000.0 49949.6 56629.5 56727.0 55561.5 53459.0 48884.8 46608.9 48635.1 51828.7 41747.7 True False 49237.30954436518 56498.37787205608 52063.12503255241 59647.67805773058 50314.646724437865 46794.111060034615 49022.08078290079 50894.86429716168 45991.206025593485 48963.7343196864 1.00558730310259 1.1538821263749137 1.0632997208225572 1.2182011622783555 1.0275900607566264 0.9556891791486691 1.001191626088677 1.039440006043388 0.9392912257328015 1.0 15.579425971874207 -6.5081327641196705 24.162386513079326 0.9905970407981368 1.111617763053085 0.5047795118261202 0.05758518093872101 351.2230093117681 575506.2579197276 0.017250655856239572 0.01887005723053019 3.1036106671926336e-07 6.5081327641196705 0.1210207222549482 TNSGISSASGGSTEPT(ph)TPDSERPAQALLR ddPTM_PC-9_Lapatinib_30min_R1 1 TNSGISSASGGSTEPTTPDSERPAQALLR 29 1 A2A2F0;Q86X10-4;Q86X10-2;Q86X10-3;Q86X10;A0A0J9YW54 A2A2F0 RALGAPB Ral GTPase-activating protein subunit beta 1 TNSGISSASGGSTEPT(0.494)T(0.494)PDS(0.012)ERPAQALLR 120.85 1.0632000000000001e-13 21607000.0 8069.7 4539.1 7983.7 4428.2 7447.3 7420.8 3475.1 4273.5 3428.2 3699.8 True False 7954.624598198261 4528.589992831471 7327.311003973221 4753.864600042158 7009.2644559551445 7103.4296827296985 3655.023674205109 4472.062411178764 3042.080015453591 4339.305500326383 1.8331561577307591 1.043620918714032 1.6885907211239435 1.0955358178133792 1.6152963775949722 1.6369969070385597 0.8423061418308055 1.0305940457159322 0.7010522801920215 1.0 12.083248444518205 -7.269028216227776 24.69210519332366 0.89603757876355 1.4628470270354799 0.5739521156956271 0.24942857630811524 368.19280791846523 1197997.8109293175 0.09705241407610647 0.06688735797841724 5.38234812121661e-08 7.269028216227776 0.5668094482719299 TNSGISSASGGSTEPTT(ph)PDSERPAQALLR ddPTM_PC-9_AZD4547_30min_R2 1 TNSGISSASGGSTEPTTPDSERPAQALLR 29 1 A2A2F0;Q86X10-4;Q86X10-2;Q86X10-3;Q86X10;A0A0J9YW54 A2A2F0 RALGAPB Ral GTPase-activating protein subunit beta 1 TNSGISSASGGSTEPT(0.215)T(0.524)PDS(0.26)ERPAQALLR 68.92699999999999 9.2731e-05 19409000.0 3801.3 2939.1 1350.3 13108.0 13314.0 5725.7 5408.7 6191.4 3301.8 9734.2 True False 5010.034328048166 3889.1065977669327 1332.3941397296535 10086.153116581212 11465.580916368632 5367.671073864293 5890.063821959724 5234.66139421816 3476.326407241704 9393.408620859887 0.5333563704364369 0.41402506318424354 0.14184351958998287 1.073747935779452 1.2205985472522811 0.5714295300583792 0.6270422228710134 0.5572696350708707 0.3700814632424109 1.0 13.197433053624096 -5.753540227933907 24.999925905125014 0.7598686728654153 0.3681700355470546 0.3371477864315743 0.26366669339471765 238.28967933959154 754151.8124561554 0.07865187456119993 0.1331344015704194 1.7638423752927907e-06 5.753540227933907 -0.3916986373183607 TNSGISSASGGSTEPTT(ph)PDSERPAQALLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TNSGISSASGGSTEPTTPDSERPAQALLR 29 1 A2A2F0;Q86X10-4;Q86X10-2;Q86X10-3;Q86X10;A0A0J9YW54 A2A2F0 RALGAPB Ral GTPase-activating protein subunit beta 1 TNSGISSASGGSTEPT(0.089)T(0.85)PDS(0.061)ERPAQALLR;TNSGISSAS(0.004)GGS(0.003)T(0.001)EPT(0.101)T(0.606)PDS(0.285)ERPAQALLR 84.291 4.4863e-08 32582000.0 14870.900000000001 15747.4 11467.900000000001 16082.9 16211.2 20342.1 19353.1 17643.6 17532.7 13058.3 True False 17388.24965633682 17310.697801059006 11741.338228252946 15181.827254465305 13034.731733072926 19275.324465779588 17519.834263689634 17180.474194939463 17789.082568890346 15425.666420554071 1.1272284245151112 1.1222009687693757 0.761155979141886 0.9841926332748995 0.8450028269575879 1.2495618626950213 1.135758662610853 1.1137589603290774 1.153213228129134 1.0 13.913045197667097 -6.763314811209676 24.99994647657661 1.1378997256208891 0.965938454529951 0.32003412072829285 0.11816668284256156 61.56394965851307 820650.9678246062 0.04177686536634852 0.038716944042834 1.7245873206235645e-07 6.763314811209676 -0.17196127109093817 TNSGISSASGGSTEPTTPDS(ph)ERPAQALLR ddPTM_PC-9_AZD4547_30min_R2 1 TNSGISSASGGSTEPTTPDSERPAQALLR 29 1 A2A2F0;Q86X10-4;Q86X10-2;Q86X10-3;Q86X10;A0A0J9YW54 A2A2F0 RALGAPB Ral GTPase-activating protein subunit beta 1 TNSGIS(0.001)S(0.001)AS(0.002)GGS(0.001)T(0.001)EPT(0.043)T(0.043)PDS(0.908)ERPAQALLR 58.383 0.00078882 20346000.0 4560.1 4173.7 4857.8 7580.2 5034.6 4762.4 4003.1 7619.2 4896.6 4130.0 True False 6010.116944027682 5522.766903848062 4793.382397969864 5832.702002922557 4335.632693521823 4464.606375145627 4359.368144967734 6441.827711798145 5155.424279392975 3985.4099570741646 1.5080297908524143 1.3857462502809943 1.202732579483206 1.463513682593536 1.0878762135438558 1.1202376727194354 1.0938317994689073 1.6163525913723884 1.2935743963408375 1.0 11.960512418568573 -4.498470056072387 1.0178287569463516 1.2420486966311266 1.7986976312140353 0.1992633733611061 0.1770695711535784 5.688577980509534 3.2507319594774504 0.0591073106898713 3.957856045248935 3.173437459859806e-05 4.498470056072387 0.5566489345829086 TNSGISSASGGSTEPTTPDS(ph)ERPAQALLR ddPTM_PC-9_Lapatinib_30min_R1 1 TNSGISSASGGSTEPTTPDSERPAQALLR 29 1 A2A2F0;Q86X10-4;Q86X10-2;Q86X10-3;Q86X10;A0A0J9YW54 A2A2F0 RALGAPB Ral GTPase-activating protein subunit beta 1 TNSGIS(0.002)S(0.002)AS(0.016)GGS(0.005)T(0.01)EPT(0.17)T(0.102)PDS(0.693)ERPAQALLR 66.437 0.00011013 19616000.0 8358.3 9799.9 6537.1 6714.1 12494.0 14271.0 12937.0 8520.8 10008.0 12431.0 True False 8239.109109275503 9777.208933654065 5999.644871935734 7207.87731158102 11759.127484149101 13660.662597325841 13606.814558772843 8916.707474709725 8880.793651087906 14579.681786733676 0.5651089804149513 0.6706050980173333 0.41150725781922914 0.49437823246180873 0.8065421218485681 0.9369657580425338 0.9332723963258195 0.6115845054192611 0.6091212264432757 1.0 13.831671611579788 -6.267285898858973 24.197346722020008 0.808714053408406 0.5362079285158914 0.5073902933828615 0.13544501620851102 287.710986548768 1190765.4686174807 0.04475784340676179 0.05214728646591716 5.403984580334362e-07 6.267285898858973 -0.2725061248925146 TNSMS(ph)SSGLGSPNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TNSMSSSGLGSPNR 14 0 F8VQD8;A0A087X050;F8VVY1;F8VX63;F8VUB4;F8VV52;F8VP97;Q9NZN8-4;Q9NZN8-5;Q9NZN8 F8VQD8 CNOT2 CCR4-NOT transcription complex subunit 2 1 T(0.003)NS(0.041)MS(0.411)S(0.411)S(0.105)GLGS(0.028)PNR 64.244 0.036708 90512000.0 14604.0 16636.0 21105.0 26377.0 25600.0 26395.0 23696.0 22135.0 21827.0 19706.0 True False 17076.168757852105 18287.51213650619 21608.22324115822 24899.18220538782 20583.86377113766 25010.799734258122 21451.343335816444 21553.97970397113 22146.178582372915 23278.541807389818 0.7335583516846936 0.7855952614137017 0.9282464262559026 1.0696194981372729 0.8842419744952956 1.0744143658654082 0.9215071765795344 0.9259162314509226 0.9513559210715925 1.0 14.50671306867469 -5.2571052391136 3.1159521915423936 0.9719564893956922 0.7455607334364784 0.680425195825443 0.058549160522000696 0.13753615277412287 2.7180155298312143 0.015142745210097066 0.04427405217959866 5.532160365477628e-06 5.2571052391136 -0.2263957559592138 TNSMSSSGLGS(ph)PNR ddPTM_PC-9_AZD4547_30min_R2 5 TNSMSSSGLGSPNR 14 0 F8VQD8;A0A087X050;F8VVY1;F8VX63;F8VUB4;F8VV52;F8VP97;Q9NZN8-4;Q9NZN8-5;Q9NZN8 F8VQD8 CNOT2 CCR4-NOT transcription complex subunit 2 1 TNS(0.001)MS(0.007)S(0.007)S(0.005)GLGS(0.98)PNR;TNSMSSSGLGS(1)PNR;TNSMSSSGLGS(0.999)PNR;TNSMS(0.007)S(0.007)S(0.007)GLGS(0.978)PNR;TNSMSSSGLGS(0.999)PNR 123.76 4.0227e-05 140673900.0 52838.299999999996 51887.8 76552.9 118335.0 90505.0 91835.0 63038.600000000006 98473.9 74729.5 85859.3 True False 69639.78029508526 68659.51662876768 75537.7585272237 91054.69400752502 77939.94298001681 86092.5429324497 68648.91327805026 83257.02146010572 78679.54880670214 82853.39204053715 0.8405181559858533 0.8286868520141587 0.9117038743599759 1.0989857115683963 0.9406970681644952 1.0390949701893648 0.828558874746647 1.0048716100768824 0.9496237494803725 1.0 16.33827314253493 -5.522197617805564 24.999983338855706 0.9772849286562778 0.8435006955439154 0.4336186615106036 0.06660342201148102 21.96385355934753 806156.1010603374 0.017787028789619946 0.03129131710990446 3.0047087534404102e-06 5.522197617805564 -0.13378423311236243 TNSMSSSGLGS(ph)PNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TNSMSSSGLGSPNR 14 0 F8VQD8;A0A087X050;F8VVY1;F8VX63;F8VUB4;F8VV52;F8VP97;Q9NZN8-4;Q9NZN8-5;Q9NZN8 F8VQD8 CNOT2 CCR4-NOT transcription complex subunit 2 1 TNS(0.001)MS(0.01)S(0.006)S(0.002)GLGS(0.981)PNR 82.34899999999999 0.008232 61315000.0 16865.0 14975.0 22052.0 24501.0 27043.0 24220.0 21540.0 20000.0 22477.0 17742.0 True False 19719.911401066536 16461.619033672785 22577.803312675715 23128.288403313756 21744.118279799834 22949.860563126786 19499.575263904713 19475.021191751628 22805.68360269373 20958.484154405283 0.9409035145760573 0.7854393911504665 1.077263181170002 1.1035286823666777 1.0374852551170508 1.0950152880356536 0.9303905339836364 0.929218976347493 1.0881361187517076 1.0 14.355246755680279 -5.2681017264756695 24.98880832869674 1.0313840321105188 0.8631714505236926 0.48732056453623407 0.06951518490252068 405.5690922454518 1521193.398828868 0.018912171854710877 0.040885928299644284 5.393842656551364e-06 5.2681017264756695 -0.16821258158682617 TNSMSSSGLGS(ph)PNR ddPTM_PC-9_Lapatinib_30min_R1 5 TNSMSSSGLGSPNR 14 0 F8VQD8;A0A087X050;F8VVY1;F8VX63;F8VUB4;F8VV52;F8VP97;Q9NZN8-4;Q9NZN8-5;Q9NZN8 F8VQD8 CNOT2 CCR4-NOT transcription complex subunit 2 1 T(0.001)NS(0.014)MS(0.069)S(0.069)S(0.014)GLGS(0.834)PNR;TNSMSSSGLGS(1)PNR;TNSMSSSGLGS(1)PNR;TNSMSS(0.006)S(0.006)GLGS(0.987)PNR;TNSMSSSGLGS(1)PNR 178.85 6.8017e-05 174965000.0 87187.0 86946.1 95596.9 80605.0 94297.6 77754.5 84836.0 81181.8 92473.0 73780.9 True False 85943.69739186246 86744.78164740233 87737.29189670527 86532.96059039734 88751.20056421463 74429.12128959228 89228.39297426393 84953.80279673156 82057.71695614015 86533.83025813056 0.9931803219098503 1.0024377909615523 1.0139074121067422 0.9999899499683462 1.0256243170962114 0.8601158768492055 1.031138835621808 0.9817409277194159 0.948273255804832 1.0 16.400976641824073 TNSS(ph)SSSPVVLK ddPTM_PC-9_AZD4547_30min_R2 4 TNSSSSSPVVLK 12 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;Q7Z589-2 E9PMC9 C11orf30;EMSY Protein EMSY 1 T(0.149)NS(0.046)S(0.74)S(0.031)S(0.031)S(0.003)PVVLK;T(0.025)NS(0.111)S(0.801)S(0.044)S(0.014)S(0.005)PVVLK;T(0.229)NS(0.027)S(0.741)S(0.003)SSPVVLK;T(0.135)NS(0.09)S(0.762)S(0.007)S(0.002)S(0.004)PVVLK 163.62 5.6141000000000003e-05 115441000.0 163239.0 154319.0 194578.0 251962.0 216806.0 196515.0 171650.0 207391.0 172104.0 172980.0 True False 215145.60641787146 204199.59887747758 191997.76858499346 193876.05367409452 186706.22924396984 184226.88598432363 186926.51746988847 175343.486321074 181201.06608272056 166924.0228510139 1.2888834257840598 1.2233086370062718 1.150210528752706 1.1614628641387126 1.1185102422951567 1.1036571179976487 1.1198299338659454 1.0504388962490725 1.085530189051635 1.0 17.348832069365187 -1.5228787452803376 0.20320391388160636 1.0123352995663835 2.306623696117578 0.9244341933216782 0.021555033433308505 13.067043639279051 0.1594504289522847 0.038419726536488036 5.4104547365427385 0.029999999999999995 1.5228787452803376 1.2942883965511944 TNSS(ph)SSSPVVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TNSSSSSPVVLK 12 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;Q7Z589-2 E9PMC9 C11orf30;EMSY Protein EMSY 1 T(0.049)NS(0.273)S(0.649)S(0.02)S(0.005)S(0.003)PVVLK;T(0.006)NS(0.324)S(0.655)S(0.011)S(0.003)S(0.001)PVVLK 156.96 0.00039749 41800000.0 62506.0 56181.0 54653.0 87855.0 114362.0 94983.0 107908.0 111380.0 93512.0 84165.0 True False 73087.03125022615 61758.27839270584 55956.1347926567 82932.76917975291 91953.58705448608 90001.92427198471 97686.17305373425 108456.39301686494 94879.43609267689 99423.44825022678 0.7351085939634914 0.6211641165097588 0.5628062170186203 0.8341369228215614 0.9248682144181852 0.9052384106158722 0.9825265042898111 1.0908532637482482 0.9542963733654296 1.0 16.6012985199174 -6.088475282479991 1.9590704045539253 0.9865094085186199 0.6371940459447322 0.8442829858865911 0.064198269129101 0.1260889709014562 0.9597414471272898 0.02223894466823008 0.033111158480485015 8.156892101049317e-07 6.088475282479991 -0.34931536257388773 TNSS(ph)SSSPVVLK ddPTM_PC-9_Lapatinib_30min_R1 3 TNSSSSSPVVLK 12 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;Q7Z589-2 E9PMC9 C11orf30;EMSY Protein EMSY 1 T(0.122)NS(0.026)S(0.395)S(0.395)S(0.037)S(0.025)PVVLK;T(0.011)NS(0.065)S(0.885)S(0.026)S(0.002)S(0.011)PVVLK;T(0.109)NS(0.256)S(0.431)S(0.145)S(0.049)S(0.01)PVVLK 158.89 0.00024498 58117000.0 74540.0 77543.0 78446.0 80053.0 98998.0 100526.0 95443.0 90390.0 106991.0 97520.0 True False 73477.0459310381 77363.45394772767 71996.47269031701 85940.36466897941 93175.1322775566 96226.73731755155 100384.57153381426 94589.84938491846 94940.54691482264 114376.20206276786 0.6424155078231664 0.6763946743508045 0.6294707412194582 0.7513832695879925 0.8146374035607823 0.8413178229571203 0.8776700897860272 0.8270063848859839 0.8300725605727034 1.0 16.803427380245566 -3.2914453754425788 0.1481300174077802 1.035892167150483 9.454039126770666e-18 0.8707082415950662 0.03937938448320456 15.297650197733908 0.24308077985928567 0.18540816530386434 3.135129300328952 0.0005111573671880028 3.2914453754425788 -1.035892167150483 TNSSS(ph)SSPVVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TNSSSSSPVVLK 12 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;Q7Z589-2 E9PMC9 C11orf30;EMSY Protein EMSY 1 T(0.008)NS(0.126)S(0.254)S(0.528)S(0.052)S(0.032)PVVLK 108.36 0.0014417 17897000.0 23531.0 15761.0 22467.0 28265.0 37193.0 40673.0 43949.0 31362.0 33756.0 30545.0 True False 27514.33354156517 17325.64791917975 23002.69848657198 26681.40368636638 29905.298642184473 38540.03627927562 39785.83255679428 30538.78073078576 34249.617639922115 36082.56670591304 0.7625381466295814 0.4801667259535754 0.6375017241443194 0.739454149806753 0.8288018667276165 1.0681068393330195 1.1026331048194076 0.8463583253289242 0.9492012560821913 1.0 15.139014346806405 -6.278972777703201 1.8487999253525513 0.9880505999158417 0.6166792637081303 0.7392717887974609 0.094880164401107 0.17824594662238205 1.199763981126129 0.03441412920090496 0.04474335595560293 5.260502390568002e-07 6.278972777703201 -0.37137133620771134 TNSSS(ph)SSPVVLK ddPTM_PC-9_Lapatinib_30min_R1 1 TNSSSSSPVVLK 12 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;Q7Z589-2 E9PMC9 C11orf30;EMSY Protein EMSY 1 T(0.003)NS(0.057)S(0.28)S(0.658)S(0.001)S(0.002)PVVLK 132.06 9.8286e-05 34812000.0 44964.0 41415.0 38141.0 52311.0 64120.0 74241.0 62152.0 72264.0 68524.0 53949.0 True False 44322.80511461227 41319.10611203002 35005.19420851766 56158.125444380414 60348.58766477031 71065.8854942237 65369.92644792842 75621.64925270191 60806.10553029045 63274.012767476095 0.7004898721611494 0.653018582271247 0.553231772057152 0.887538548420413 0.9537657724750863 1.1231449118832044 1.0331243995564898 1.1951454624918734 0.9609965113757699 1.0 15.94932547241757 -6.073640902030063 2.0393737180399607 1.066029535609415 0.6369217683665751 0.8372882629762918 0.07987241413687839 0.11345735536212818 0.9364318340472416 0.025005511281857226 0.037346344306337445 8.440323605400964e-07 6.073640902030063 -0.42910776724283983 TNST(ph)GGSSGSSVGGGSGK ddPTM_PC-9_AZD4547_30min_R2 1 TNSTGGSSGSSVGGGSGK 18 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 T(0.023)NS(0.114)T(0.853)GGS(0.009)S(0.001)GSSVGGGSGK 193.06 4.6892e-13 30015000.0 14291.0 13374.0 18810.0 27146.0 20965.0 19268.0 20198.0 26407.0 16242.0 20981.0 True False 18835.240728733945 17696.883957175654 18560.56710976433 20887.90910151918 18054.37163224189 18063.168914057187 21995.582871289334 22326.404922492326 17100.518961299815 20246.46157611937 0.9302979020763827 0.8740729282814073 0.9167314021753042 1.0316819570169433 0.8917297259258852 0.8921642355206715 1.0863914560375847 1.1027312026130156 0.8446176581032715 1.0 14.305382173342188 -7.246384040958849 24.78301834705304 1.0169960177569122 0.9238295656253201 0.22861399282968664 0.07642159128107166 1026.786643078704 1690224.411462726 0.029476408422781486 0.02273592102513957 5.670429549336568e-08 7.246384040958849 -0.09316645213159203 TNST(ph)GGSSGSSVGGGSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TNSTGGSSGSSVGGGSGK 18 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 TNS(0.049)T(0.951)GGSSGSSVGGGSGK;T(0.015)NS(0.34)T(0.642)GGS(0.002)SGSSVGGGSGK;T(0.004)NS(0.145)T(0.851)GGSSGSSVGGGSGK;TNS(0.119)T(0.877)GGS(0.004)SGSSVGGGSGK 222.13 5.4322e-82 122686600.0 52659.399999999994 59800.1 60954.9 71567.6 77549.6 66486.7 66468.3 68323.4 58929.9 48285.6 True False 61573.59634944105 65736.6587229072 62408.295988745565 67557.89939728988 62354.312574461626 63000.02040885389 60171.941435181 66529.98314462614 59791.638303082334 57039.39705140074 1.0794924128309833 1.1524781488077263 1.0941261516580667 1.1844076706563087 1.0931797283598805 1.1045001115997382 1.054918960327673 1.1663865079897848 1.0482515838868602 1.0 15.799671111058606 -9.379327357060973 0.4455517949232324 0.9859376507963523 1.123151330545835 0.42326450397717297 0.04122546961844945 3.3394271317865845 0.9490198244722726 0.1226908096979585 0.02363667464341245 4.1751553836902566e-10 9.379327357060973 0.13721367974948262 TNST(ph)GGSSGSSVGGGSGK ddPTM_PC-9_Lapatinib_30min_R1 1 TNSTGGSSGSSVGGGSGK 18 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 T(0.001)NS(0.357)T(0.641)GGS(0.001)SGSSVGGGSGK 134.52 0.0001356 31308000.0 37603.0 35896.0 37150.0 36969.0 36054.0 32204.0 34709.0 37328.0 34280.0 32357.0 True False 37066.77432445437 35812.88501744367 34095.670403147036 39687.82358496875 33933.37460489126 30826.709991190608 36506.06218755869 39062.395152563666 30419.02541559684 37949.86433700763 0.9767300877623402 0.9436894081995428 0.8984398494910535 1.0457961913256777 0.8941632650791954 0.812300927282348 0.9619550115745477 1.029315804812275 0.8015582123157439 1.0 15.211807107860121 -1.5228801612059661 0.6194028465942986 0.9269232303021028 4.253387292008397 0.030325938817728826 0.07864602011936841 907.5754012621327 6.5623349504769015 0.03469728129543728 4108.4699121643 0.02999990219148209 1.5228801612059661 3.3264640617062944 TNSTGGSS(ph)GSSVGGGSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TNSTGGSSGSSVGGGSGK 18 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 TNS(0.009)T(0.068)GGS(0.285)S(0.599)GS(0.036)S(0.002)VGGGSGK 190.96 3.7424999999999996e-11 6059300.0 6873.9 6922.1 8103.1 7637.1 7865.3 5804.5 8547.7 7852.4 8419.4 5685.6 True False 8037.515504286462 7609.280341434816 8296.308635177878 7209.218046812271 6324.150926528472 5500.101801761745 7737.999976011064 7646.282820305532 8542.517797060089 6716.354272815164 1.1967080915934967 1.1329480298908328 1.235239878390226 1.0733826349798135 0.941604726261365 0.8189118051773606 1.1521131348492248 1.1384573400563915 1.2718980342708288 1.0 12.713462615912823 -5.872578302277643 6.352090628034222 1.0500554662978538 1.1819814661154044 0.20558155519816868 0.1186233632576644 0.37949996195990504 19.74126786057486 0.0370223224713584 0.05549155472846373 1.3409781383915362e-06 5.872578302277643 0.1319259998175506 TNT(ph)PQGVLPSSQLK ddPTM_PC-9_AZD4547_30min_R2 1 TNTPQGVLPSSQLK 14 0 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YF61 Q14004 CDK13 Cyclin-dependent kinase 13 1 T(0.005)NT(0.995)PQGVLPSSQLK 179.9 0.00013025 16107000.0 130860.0 131050.0 93042.0 144960.0 137640.0 137970.0 124040.0 129810.0 143220.0 140700.0 True False 172470.75794290964 173409.34967757354 91808.20228743725 111541.7116096743 118531.06183934017 129342.7140892915 135079.31970267973 109750.8472370479 150790.316810575 135774.13582574675 1.2702769706025567 1.277189861109689 0.6761832931513877 0.8215240033111131 0.8730017769471468 0.9526314662410419 0.9948825590467484 0.8083339773777144 1.1105967708319653 1.0 17.05084915527302 -5.2377448016151735 24.49735369028749 0.8986369813826127 1.2737336013954814 0.6231333967619951 0.1147378733131523 380.15684001148855 393034.62982535595 0.02913374855699321 0.07697580959528329 5.784358457164622e-06 5.2377448016151735 0.3750966200128687 TNT(ph)PQGVLPSSQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TNTPQGVLPSSQLK 14 0 Q14004;A0A2R8Y4Z0;Q14004-2;A0A2R8Y7W5;A0A2R8YF61 Q14004 CDK13 Cyclin-dependent kinase 13 1 T(0.028)NT(0.972)PQGVLPSSQLK 145.94 0.00046482 15332000.0 35914.0 41793.0 24625.0 32299.0 35743.0 33313.0 35775.0 38465.0 27194.0 28578.0 True False 41993.53086616684 45941.932839685265 25212.15339083254 30489.391744770855 28739.41573327237 31566.00763581512 32386.133011429498 37455.33450703633 27591.660804006446 33758.96517667649 1.2439223372634503 1.360880957080574 0.7468283834793372 0.9031494770413009 0.8513121057729566 0.9350407357161397 0.9593342936294903 1.1094929690828794 0.8173135835060806 1.0 15.042983060923977 -5.250842600341965 24.990964352846312 0.9187765785510545 1.3024016942357615 0.713188572811193 0.09817113829024833 369.3584998452936 871074.0452094635 0.0252279776920432 0.06527470617841269 5.612513513178645e-06 5.250842600341965 0.3836251156847069 TNT(ph)PVKEDWNVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TNTPVKEDWNVR 12 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347;A0A494C0Q7 A0A494C1K3 GTF2I General transcription factor II-I 1 T(0.008)NT(0.992)PVKEDWNVR;T(0.472)NT(0.528)PVKEDWNVR 135.91 0.00063688 44181000.0 126440.7 140402.7 107268.1 156583.0 166305.0 116183.7 152357.0 136677.2 119386.4 98407.7 True False 147844.61319234123 154340.95216688118 109825.77832053452 147810.16215893516 133718.72908043154 110090.82224228542 137924.6419908419 133089.56832146365 121132.20024312127 116248.23701507522 1.2718009063068074 1.3276842396058535 0.9447522056295113 1.2715045488368735 1.150286081870564 0.9470321879204817 1.1864665265672427 1.1448738642307703 1.0420132240578641 1.0 16.82684931135516 -1.5228787494307294 0.4652302934865571 1.0796931159941907 6.946629020501638 0.28654401695366793 0.11188153593041211 124.46260577275316 1.4470956044754268 0.06621433172902468 700.1842715065308 0.029999999713301088 1.5228787494307294 5.866935904507447 TNT(ph)PVKEDWNVR ddPTM_PC-9_Lapatinib_30min_R1 1 TNTPVKEDWNVR 12 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347;A0A494C0Q7 A0A494C1K3 GTF2I General transcription factor II-I 1 T(0.046)NT(0.954)PVKEDWNVR 60.657 0.042572000000000006 23421000.0 105100.0 106810.0 76580.0 120800.0 106090.0 88190.0 84660.0 87369.0 73773.0 85878.0 True False 103601.25472702074 106562.68800738668 70283.88800734859 129684.03497698667 99849.99478096505 84418.31928093093 89043.28055543857 91428.48269621567 65463.90787587 100721.89787475795 1.0285871981467536 1.0579892779610987 0.6978014661195391 1.2875455855512326 0.9913434604372023 0.8381327304406077 0.8840508611757784 0.9077319294549222 0.6499471242814617 1.0 16.62001784716461 -6.722334127281734 6.144241562275664 0.8518162495498168 1.0141685740118833 0.20113463371646811 0.15630108674631715 0.3121408035098926 30.638524804964195 0.05173089495395529 0.050753302395157636 1.895247239380834e-07 6.722334127281734 0.1623523244620665 TNTMNGS(ph)KSPVISR ddPTM_PC-9_AZD4547_30min_R2 1 TNTMNGSKSPVISR 14 1 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 1 TNTMNGS(0.714)KS(0.279)PVIS(0.007)R 150.01 0.0011084 36318000.0 19173.0 14848.0 21628.0 26443.0 26965.0 24750.0 24215.0 28644.0 15944.0 21409.0 True False 25269.61517682567 19647.325631534626 21341.198588515836 20346.97489027746 23221.37519978069 23202.378587446317 26370.088089329187 24217.72797363844 16786.767289678868 20659.477426392445 1.223148807459369 0.9510078704331216 1.0329979867376748 0.9848736475920846 1.1240059329920624 1.1230864222056904 1.2764160266532902 1.1722333277752872 0.8125455907337619 1.0 14.33451614179274 -4.726240501382393 23.629870963671333 1.0670348260274092 1.2231512413925643 0.13780314352058898 0.1232576048733081 6505.133641592588 4366536.825430709 0.03178854909274417 5.861234418649733 1.8782763864335406e-05 4.726240501382393 0.15611641536515508 TNTMNGSKS(ph)PVISR ddPTM_PC-9_AZD4547_30min_R2 1 TNTMNGSKSPVISR 14 1 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 1 TNTMNGS(0.011)KS(0.979)PVIS(0.011)R 83.37 0.017683 39452000.0 14044.0 14968.0 17946.0 27154.0 22756.0 19590.0 20394.0 24711.0 20015.0 22454.0 True False 18509.6998666531 19806.113284806717 17708.024314291903 20894.06482511795 19596.72219715221 18365.03420315447 22209.026491587025 20892.48275228947 21072.952038567655 21667.892294465695 0.854245517519983 0.9140765984823312 0.817247200310978 0.9642869062282816 0.9044129410850683 0.8475690184155649 1.0249740117666888 0.9642138916126015 0.9725427721435557 1.0 14.40327120422191 -7.261964117571966 24.999989218178833 0.9874504944411479 0.8866153717897503 0.6186761322128785 0.041007068816842476 34.282767490890144 1633268.7222156494 0.016238444697233286 0.011694182392865689 5.470611605021121e-08 7.261964117571966 -0.1008351226513976 TNTMNGSKS(ph)PVISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TNTMNGSKSPVISR 14 1 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 1 TNTMNGS(0.004)KS(0.994)PVIS(0.002)R;TNTMNGS(0.001)KS(0.996)PVIS(0.004)R 156.29 0.00076577 131785000.0 75289.0 82629.0 90683.0 115914.0 119812.0 103605.0 119419.0 111616.0 97290.0 85334.0 True False 88033.94067446774 90831.86104396303 92845.22663719249 109419.71437825818 96335.69867763866 98171.77141382123 108106.76780131122 108686.19826692731 98712.68219540289 100804.37869642781 0.8733146497493108 0.9010705905693145 0.921043587965516 1.085465887427127 0.9556697826366594 0.9738839987245527 1.0724411895526338 1.0781892579709815 0.9792499440195543 1.0 16.62119878179071 -5.612514068284532 6.1611638206241635 1.0211835251295533 0.8928743181503915 0.6242480666723387 0.04388925402584086 0.13535168261620908 7.506774966053934 0.012468355476476184 0.021842182864331088 2.4405400093184636e-06 5.612514068284532 -0.12830920697916182 TNTMNGSKS(ph)PVISR ddPTM_PC-9_Lapatinib_30min_R1 3 TNTMNGSKSPVISR 14 1 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;Q8N8S7 A0A0U1RRM6;Q8N8S7 ENAH Protein enabled homolog 1 TNT(0.002)MNGS(0.099)KS(0.865)PVIS(0.034)R;TNTMNGS(0.026)KS(0.974)PVISR;TNTMNGS(0.217)KS(0.783)PVISR 209.33 2.2266e-10 67148000.0 73822.0 61108.0 59917.0 63786.0 61149.0 59696.0 51303.0 49048.0 63102.0 52360.0 True False 72769.28474270311 60966.508180464356 54990.85554630851 68477.0352238584 57552.33604355953 57142.941238172745 53959.218312493096 51326.949138527176 55994.78826648169 61410.35623468551 1.1849676374552913 0.9927724233918307 0.8954655031824881 1.1150730824971429 0.9371763912851736 0.9305098478796567 0.8786664273088209 0.8358028235885225 0.9118134415715208 1.0 15.906194351570596 -6.458770926960823 5.804770574342689 0.9023273964865325 1.0325835337025668 0.38184862559784893 0.08116540945851856 0.24902208000538528 16.597280610583628 0.02583939895331178 0.02900785337725812 3.477195212775922e-07 6.458770926960823 0.13025613721603435 TNTMNGSKS(ph)PVISRR ddPTM_PC-9_Lapatinib_30min_R1 1 TNTMNGSKSPVISRR 15 2 Q8N8S7 Q8N8S7 ENAH Protein enabled homolog 1 T(0.003)NT(0.002)MNGS(0.226)KS(0.764)PVIS(0.005)RR 42.958 0.046058 21688000.0 212970.0 31453.0 42143.0 34295.0 26247.0 29707.0 18221.0 14619.0 43218.0 20310.0 True False 209933.00874608502 31380.172510966575 38678.16521668442 36817.168704766256 24703.20306358743 28436.500860399312 19164.394223962277 15298.252109283345 38350.333734284264 23820.55643862612 8.813102636245267 1.3173568212740066 1.6237305503899149 1.5456048980058894 1.037053988526064 1.1937798738524943 0.8045317611844842 0.6422289986675764 1.6099680052854453 1.0 14.53991949392151 -4.761291487548093 7.252136964485323 1.1838453600586623 8.955573916220896 0.9812341924719586 0.3160171930156151 0.013387304520119785 4.520391044470278 0.08484587120305859 0.5110493471008577 1.732640702489694e-05 4.761291487548093 7.771728556162234 TNYNDRYDEIR ddPTM_PC-9_AZD4547_30min_R2 2 TNYNDRYDEIR 11 1 P62424;Q5T8U2 P62424 RPL7A 60S ribosomal protein L7a 0 ; 79.23 0.022698 16328500.0 111184.0 110852.0 146064.0 179121.0 150331.0 165540.0 124637.0 152373.0 142289.0 124819.0 False True 146538.19922913396 146682.74117099112 144127.09592347775 137827.42084186326 129460.13555194631 155188.75763094425 135729.45154613777 128827.25403320786 149810.10605124908 120449.12480194663 1.216598289693556 1.2177983145347064 1.1965806821798382 1.144279139167608 1.0748117577841798 1.2884174782184568 1.1268612517468801 1.0695574106083154 1.2437625121608848 1.0 16.87806438525289 -14.522878745279218 0.16891339983587406 0.35073273770867214 1.2120165450223084 0.3727296994001892 0.068004542049272 145.89372560475977 1.3681350190949098 31.88552720272684 0.24874678287469396 3.0000000000077315e-15 14.522878745279218 0.8612838073136362 TNYNDRYDEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TNYNDRYDEIR 11 1 P62424;Q5T8U2 P62424 RPL7A 60S ribosomal protein L7a 0 108.98 0.0027445 8828300.0 57681.0 63032.0 75518.0 70881.0 90580.0 70805.0 68336.0 71482.0 63107.0 65140.0 False True 67445.25404832013 69289.4003960242 77318.63552361002 66909.7673693026 72831.49923397052 67091.8611549213 61862.7193702039 69605.67324143961 64029.82048828548 76949.36635204383 0.8764887515740893 0.9004544635107814 1.0047988591598895 0.8695298030550376 0.9464860165419161 0.8718962135175437 0.8039405950034932 0.9045646058083601 0.8321032845851992 1.0 16.231621826122065 -6.783714987638326 23.492026446153634 0.8716261545998912 0.9204475897339368 0.07224557340791682 0.06035405078748996 243.30785177421168 256591.22566226922 0.02028524168117599 0.017908110303568602 1.6454512213577148e-07 6.783714987638326 0.04882143513404558 TNYNDRYDEIR ddPTM_PC-9_Lapatinib_30min_R1 2 TNYNDRYDEIR 11 1 P62424;Q5T8U2 P62424 RPL7A 60S ribosomal protein L7a 0 ; 93.839 0.0089223 21028000.0 183158.0 186695.0 189732.0 172134.0 182715.0 176698.0 174649.0 173911.0 180584.0 154486.0 False True 180546.1333329369 186262.71919800632 174132.9673466998 184793.3085821908 171968.06293151143 169141.0384431561 183691.47065587994 181991.53995331906 160244.7282861767 181188.6992603444 0.9964536092480899 1.028004064041385 0.9610586535338694 1.0198942281530872 0.9491103122519571 0.9335076587757971 1.013813065636833 1.004430964493106 0.8844079621981613 1.0 17.467133451733353 -6.264674565894415 24.988533078523854 0.9653780790383643 1.000378170129977 0.17443876074905085 0.03951173341975954 547.762687164287 4230905.426655689 0.01204521128703189 0.014247131965916619 5.436575631022261e-07 6.264674565894415 0.03500009109161273 TPAAAAAMNLAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 TPAAAAAMNLASPR 14 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 TPAAAAAMNLAS(1)PR;TPAAAAAMNLAS(1)PR;TPAAAAAMNLAS(1)PR;TPAAAAAMNLAS(1)PR 110.57 0.00048198 210672000.0 53796.6 49751.7 72242.0 97105.0 80752.0 75820.0 53589.700000000004 71773.3 60808.0 65794.0 True False 70902.79976120687 65832.96407747986 71284.0238779157 74718.94250729459 69540.97868098239 71078.96341414878 58359.07948299504 60682.38567135675 64022.18673800756 63490.572086134955 1.1167453281885076 1.036893540479791 1.1227497490683767 1.1768509882999099 1.0952961423412455 1.1195199708977102 0.9191770929992844 0.9557700250209046 1.0083731274487713 1.0 15.95425475703423 -7.251683099535571 24.92033033538026 0.9671442299008272 1.110725350747499 0.7529427266637756 0.03940750484649575 329.56652248286366 841808.7574974801 0.015919807810196293 0.012174031281951738 5.6016620023621243e-08 7.251683099535571 0.14358112084667185 TPAAAAAMNLAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 TPAAAAAMNLASPR 14 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 TPAAAAAMNLAS(1)PR;TPAAAAAMNLAS(1)PR;TPAAAAAMNLAS(1)PR;TPAAAAAMNLAS(1)PR 135.61 4.2483999999999995e-05 194915000.0 282287.0 233275.0 199472.0 222948.0 261501.0 284420.0 234284.0 236110.0 267117.0 207930.0 True False 278261.53561490437 232734.86606987298 183072.18214418663 239344.33965272547 246120.025310747 272256.0196154029 246414.079159584 247080.5325619324 237031.47059329014 243870.4234506905 1.1410220709735537 0.9543382209976394 0.7506944858411787 0.9814406202526639 1.0092245784799376 1.1163962228919155 1.010430357535373 1.013163175205176 0.9719566122015483 1.0 17.89575527345483 -5.997989920101963 24.997884489960448 1.022462185729248 0.9353864982297677 0.09975255285570794 0.09436192708332178 134.30497367678632 1670190.1567210841 0.027801510800074695 0.040931605167909516 1.0046391075036223e-06 5.997989920101963 -0.08707568749948025 TPAAPAS(ph)PAAVPSEGSGGSTTGWR ddPTM_PC-9_AZD4547_30min_R2 3 TPAAPASPAAVPSEGSGGSTTGWR 24 0 P07199 P07199 CENPB Major centromere autoantigen B 1 TPAAPAS(0.981)PAAVPS(0.013)EGS(0.005)GGSTTGWR;T(0.004)PAAPAS(0.996)PAAVPSEGSGGSTTGWR;T(0.111)PAAPAS(0.887)PAAVPS(0.002)EGSGGSTTGWR 156.58 3.6691000000000003e-10 217490000.0 63146.4 52688.8 78741.0 110454.9 91425.5 82891.5 73190.4 91405.6 66505.6 78951.5 True False 83225.6416732856 69719.42421435892 77696.84289154457 84991.22931619365 78732.6474440035 77708.28140126493 79704.20381140796 77280.9648117305 70020.95024212661 76187.43201596645 1.0923801927835575 0.9151040056022358 1.0198118093186523 1.1155544565195767 1.0334072872741484 1.019961945757402 1.0461594741072846 1.0143531914231587 0.9190616928452511 1.0 16.217265407928444 -8.077342984943211 6.433861314911707 0.9603831986001166 1.031877173381735 0.23698403241077637 0.052988646536941325 0.37008678880649903 24.996308745756323 0.0366025268548908 0.013669993097553693 8.368681028049421e-09 8.077342984943211 0.07149397478161834 TPAAPAS(ph)PAAVPSEGSGGSTTGWR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TPAAPASPAAVPSEGSGGSTTGWR 24 0 P07199 P07199 CENPB Major centromere autoantigen B 1 T(0.005)PAAPAS(0.973)PAAVPS(0.016)EGS(0.004)GGS(0.001)TTGWR;TPAAPAS(0.99)PAAVPS(0.007)EGSGGS(0.001)T(0.001)T(0.001)GWR;TPAAPAS(1)PAAVPSEGSGGSTTGWR;T(0.001)PAAPAS(0.999)PAAVPSEGSGGSTTGWR 214.05 5.518699999999999e-86 96665000.0 107233.0 108447.0 110692.0 136069.0 148117.0 126844.0 130460.0 127323.0 128321.0 96403.5 True False 125385.4289517089 119212.90145874553 113331.31708174774 128445.49507164993 119094.53711678114 120192.07734389996 118101.88435139298 123980.90615986966 130197.45186551861 113880.69142031377 1.1010244791097479 1.0468227754145916 0.9951758780903569 1.1278952864588783 1.045783403941797 1.0554210362166836 1.037066801039164 1.0886911961420902 1.1432794290384356 1.0 16.797163631899295 -7.789222930078668 23.86309700633924 1.0869890435308005 1.057641050283617 0.020466417944389192 0.04705756513087126 381.6515448434194 327789.6887219191 0.024698838572278635 0.011870635445545216 1.6247145505408327e-08 7.789222930078668 -0.0293479932471834 TPAAPAS(ph)PAAVPSEGSGGSTTGWR ddPTM_PC-9_Lapatinib_30min_R1 3 TPAAPASPAAVPSEGSGGSTTGWR 24 0 P07199 P07199 CENPB Major centromere autoantigen B 1 TPAAPAS(1)PAAVPSEGSGGSTTGWR;TPAAPAS(0.999)PAAVPSEGSGGSTTGWR;T(0.005)PAAPAS(0.995)PAAVPSEGSGGSTTGWR 174.91 8.8369e-36 205108000.0 166302.9 144770.2 151136.4 144779.3 156477.2 147352.5 143417.2 133028.1 174607.5 125498.6 True False 163931.39014978285 144434.99349655487 138710.54859537497 155426.85269158662 147273.51874201166 141050.57707045457 150842.6408702511 139209.07116895527 154941.36465151177 147190.86579362702 1.1137334457943018 0.9812768796337126 0.9423855743185715 1.0559544700926422 1.0005615358530504 0.9582834934079292 1.02480979411959 0.9457724867529291 1.0526561129734202 1.0 17.167328619451865 -4.757679233245443 24.96880818462814 0.9941521330753313 1.113733619195466 0.4591783276720617 0.03837983283580693 93.039937839126 617729.2359506158 0.009074044400115088 0.06595115481347082 1.7471120808079018e-05 4.757679233245443 0.11958148612013475 TPADRGPS(ph)PAPAPAASPQPGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPADRGPSPAPAPAASPQPGSR 22 1 Q8IX07 Q8IX07 ZFPM1 Zinc finger protein ZFPM1 1 T(0.007)PADRGPS(0.99)PAPAPAAS(0.002)PQPGSR 82.541 0.00016078 12409000.0 3712.2 9719.7 9628.8 9535.9 9995.3 9860.7 8494.3 9110.4 6724.6 6193.4 True False 4340.602140707929 10684.607580740527 9858.387109427347 9001.634438804922 8036.792716861417 9343.587533229746 7689.6584105935835 8871.261653266703 6822.934553306676 7316.214393072574 0.5932852575804597 1.4604011045462728 1.3474710526200344 1.230367776992457 1.098490597059475 1.277106852155236 1.0510433398281231 1.212548071536359 0.9325771753992113 1.0 12.836881636852416 -8.261930658834162 24.744330667369898 0.9662885734616323 1.1759007642114745 0.10453165993770863 0.22095805664916154 78.56440320744142 3956397.1140209152 0.16829437440565995 0.053605218254707224 5.4710330858779305e-09 8.261930658834162 0.20961219074984216 TPADRGPS(ph)PAPAPAASPQPGSR ddPTM_PC-9_Lapatinib_30min_R1 2 TPADRGPSPAPAPAASPQPGSR 22 1 Q8IX07 Q8IX07 ZFPM1 Zinc finger protein ZFPM1 1 TPADRGPS(1)PAPAPAASPQPGSR;T(0.005)PADRGPS(0.985)PAPAPAAS(0.01)PQPGSR 85.17 0.00010829 25915000.0 18632.1 16815.6 22521.0 16640.7 18147.0 18541.2 16917.5 10199.4 23444.0 9603.7 True False 18366.402837291324 16776.664511347375 20669.410313574004 17864.51258974789 17079.62913837472 17748.23609764822 17793.40537203676 10673.301358740306 20803.489843735497 11263.686748874125 1.6305853710932754 1.489447006596158 1.835048397065911 1.586027114215828 1.5163444722112798 1.5757039851469827 1.5797141529895016 0.9475850666574307 1.8469520954864032 1.0 13.45939149682178 -12.423967717921512 0.15295229178629946 2.344454859639562e-16 1.751453189145795 0.35073777016499774 0.23139817955581166 66.83898400966153 1.1000126062060651 23.21039553582311 1.1921599471714317 3.76731801259076e-13 12.423967717921512 1.7514531891457947 TPADTGFAFPDWAYKPES(ph)SPGSR ddPTM_PC-9_AZD4547_30min_R2 2 TPADTGFAFPDWAYKPESSPGSR 23 1 P50548 P50548 ERF ETS domain-containing transcription factor ERF 1 TPADTGFAFPDWAY(0.009)KPES(0.478)S(0.478)PGS(0.034)R;TPADTGFAFPDWAY(0.069)KPES(0.417)S(0.417)PGS(0.097)R 50.47 0.0144 30607000.0 23520.3 23603.8 35516.0 44938.0 42409.0 37383.0 29976.0 41796.0 31619.0 42186.0 True False 30999.266147368347 31233.266752533447 35045.03463425784 34578.238385179015 36521.24238262559 35045.435100384064 32643.805928793383 35337.38857653232 33290.31578853212 40709.08098041905 0.7614828289117828 0.7672309470104854 0.8608652858342443 0.8493986489601926 0.8971276556253432 0.8608751231019147 0.8018801982902772 0.8680468270342311 0.817761418012474 1.0 15.313063032126422 -14.522878745280336 0.1665608873042515 1.6060334017713527 0.7952862657370501 0.6085224453815496 0.0411719131642932 102.01912378767092 0.9512224182957197 20.607457079136257 0.17134029986943064 3.0000000000000132e-15 14.522878745280336 -0.8107471360343026 TPADTGFAFPDWAYKPES(ph)SPGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPADTGFAFPDWAYKPESSPGSR 23 1 P50548 P50548 ERF ETS domain-containing transcription factor ERF 1 TPADTGFAFPDWAY(0.001)KPES(0.408)S(0.408)PGS(0.182)R 49.13399999999999 0.017808 9224400.0 4333.7 7722.4 9156.1 11361.0 14419.0 16078.0 13790.0 16892.0 17390.0 14298.0 True False 5067.309815523393 8489.028836436366 9374.416148702618 10724.480002858963 11593.700457657576 15234.841376298615 12483.711369045783 16448.602898553436 17644.29585135223 16890.11421709427 0.30001631430028064 0.502603400268586 0.5550238457958379 0.6349560378937434 0.6864193047270065 0.9019975342072954 0.7391134961308419 0.9738597789887066 1.0446522518772943 1.0 14.043891463750224 -5.416635998223702 0.33068153321861976 1.0546603678589157 1.840029788353014e-16 0.9121432710837966 0.06881704061150047 1.2414575074403496 0.15083070387947986 0.07439366311250074 0.5078577450966226 3.831457404880886e-06 5.416635998223702 -1.0546603678589155 down TPADTGFAFPDWAYKPES(ph)SPGSR ddPTM_PC-9_Lapatinib_30min_R1 1 TPADTGFAFPDWAYKPESSPGSR 23 1 P50548 P50548 ERF ETS domain-containing transcription factor ERF 1 TPADTGFAFPDWAYKPES(0.494)S(0.494)PGS(0.011)R 102.46 1.8595e-06 8023600.0 17718.0 24417.0 26965.0 22495.0 30987.0 36463.0 37576.0 36613.0 41047.0 31235.0 True False 17465.338070916747 24360.463936676006 24748.041787910086 24149.357341120198 29164.405582785992 34903.56248940451 39521.50141921992 38314.173642327856 36423.85461592777 36633.92813197865 0.47675308004087136 0.664970020384223 0.6755497717512557 0.6592074225324375 0.796103695943206 0.9527660359997359 1.0788223768097813 1.0458658297383752 0.9942656022227792 1.0 15.16089278419087 -6.5527850125476625 1.3547488613982213 1.0394024311867098 0.6058642641013493 0.921231424203859 0.05510193635781323 0.1095488040992021 0.41675087268711847 0.024259312932550296 0.02636227848139129 2.800367233692459e-07 6.5527850125476625 -0.4335381670853605 TPADTGFAFPDWAYKPESS(ph)PGSR ddPTM_PC-9_Lapatinib_30min_R1 1 TPADTGFAFPDWAYKPESSPGSR 23 1 P50548 P50548 ERF ETS domain-containing transcription factor ERF 1 TPADTGFAFPDWAYKPES(0.245)S(0.732)PGS(0.023)R 113.05 1.0555999999999999e-07 10761000.0 9794.9 10869.0 11685.0 9933.9 13756.0 14861.0 16285.0 17639.0 17669.0 11921.0 True False 9655.222929835329 10843.833498289372 10724.304405404386 10664.472144518948 12946.89912533656 14225.429672683009 17128.157616883032 18458.572334335367 15678.931157181467 13981.528966265969 0.6905698906844191 0.7755828081787698 0.7670337365304987 0.762754357570601 0.926000236209808 1.0174444945903638 1.2250561192705829 1.3202112858237047 1.1214031880927269 1.0 13.77123451647414 -6.718483461005248 1.5365677981995618 1.191598184200879 0.7474280087648514 0.8288758713559381 0.08425649127460871 0.14100262126402807 0.6919107042127529 0.036120755416973224 0.033955056382575004 1.912126141652355e-07 6.718483461005248 -0.44417017543602755 TPALIALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPALIALR 8 0 A0A0A0MSS8;P42330;S4R3Z2;B4DK69;P52895;H0Y804;Q04828;P42330-2 A0A0A0MSS8;B4DK69;Q04828;P42330-2 AKR1C3;AKR1C2;AKR1C1 Aldo-keto reductase family 1 member C3;Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 102.77 0.019242 7907800.0 27235.0 28022.0 29492.0 42395.0 38764.0 37693.0 35388.0 38226.0 36582.0 25160.0 False True 31845.347584230476 30803.83896905365 30195.201129032826 40019.74559644445 31168.47246970234 35716.31272526582 32035.792453066864 37222.6080037949 37116.942543655365 29721.308833549592 1.0714651821888563 1.036422693952229 1.0159445298367311 1.3465001094187994 1.0486911139834858 1.2017072641481061 1.0778728700165676 1.2523879150899908 1.2488327062419786 1.0 14.85921002860545 TPALIALR ddPTM_PC-9_Lapatinib_30min_R1 2 TPALIALR 8 0 A0A0A0MSS8;P42330;S4R3Z2;B4DK69;P52895;H0Y804;Q04828;P42330-2 A0A0A0MSS8;B4DK69;Q04828;P42330-2 AKR1C3;AKR1C2;AKR1C1 Aldo-keto reductase family 1 member C3;Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 ; 102.77 0.019242 55078000.0 93139.0 89078.0 98197.0 94319.0 87843.0 85604.0 85633.0 83267.0 94675.0 84900.0 False True 91810.82078039943 88871.74536393581 90123.62171138161 101255.53389896039 82676.24744598282 81942.91647267046 90066.65773451295 87135.88880112846 84011.7045280522 99574.85187786102 0.9220281933536293 0.8925119514407746 0.9050841654469912 1.0168785791733932 0.8302924472073923 0.8229278269294543 0.9045120935252722 0.875079271099592 0.8437040371508797 1.0 16.603493808065757 -6.300474963259374 24.999984368742357 0.8716033190501598 0.9290790629636249 0.17295621471147127 0.056662536920751565 888.9282669843576 569303.8246194386 0.017155443607645954 0.01945273680425841 5.006394131714617e-07 6.300474963259374 0.057475743913465105 TPAPPEPGS(ph)PAPGEGPSGR ddPTM_PC-9_AZD4547_30min_R2 3 TPAPPEPGSPAPGEGPSGR 19 0 P0C1Z6-2;P0C1Z6 P0C1Z6-2 TFPT TCF3 fusion partner 1 TPAPPEPGS(1)PAPGEGPSGR;TPAPPEPGS(1)PAPGEGPSGR;TPAPPEPGS(0.997)PAPGEGPS(0.003)GR 128.44 3.4621e-05 82973000.0 53985.0 60250.9 82618.7 90941.0 74306.0 76241.0 63937.1 90900.5 66269.1 59299.5 True False 71151.10704224362 79725.82515443364 81523.12205590031 69975.95747444403 63989.89451492321 71473.63821759558 69627.37803742512 76853.91641068691 69771.94933495091 57223.44255436308 1.2433908878279922 1.393237134915345 1.4246455371581708 1.222854731397292 1.1182461532986574 1.249027234768244 1.2167631818249685 1.3430495087336733 1.2192896166403582 1.0 15.804318672154812 -14.522878745272333 0.1554229863946411 0.03353350205590169 1.3481011016423623 0.4930144447007482 0.08481267799461546 127.98086123639898 1.1565146699762965 38.340167988101 0.43151668340703103 3.0000000000552927e-15 14.522878745272333 1.3145675995864605 TPAPPEPGS(ph)PAPGEGPSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TPAPPEPGSPAPGEGPSGR 19 0 P0C1Z6-2;P0C1Z6 P0C1Z6-2 TFPT TCF3 fusion partner 1 T(0.001)PAPPEPGS(0.999)PAPGEGPSGR;TPAPPEPGS(1)PAPGEGPSGR;T(0.041)PAPPEPGS(0.959)PAPGEGPSGR;TPAPPEPGS(0.994)PAPGEGPS(0.006)GR 156.08 1.656e-05 87871000.0 73510.4 93029.0 92385.0 85594.0 103440.0 84419.0 96996.0 72462.0 75955.0 62932.0 True False 85954.25882341883 102264.30431275765 94587.80877206342 80798.44567949217 83171.67455025288 79991.91902884384 87807.83668977262 70559.94927983548 77065.69818225739 74341.07343056223 1.156214927454657 1.375609734883327 1.2723492466168451 1.086861434076028 1.1187849557746676 1.0760124294352535 1.1811483563226852 0.9491381550434769 1.0366503283577155 1.0 16.181871899357517 -6.203742743117802 0.571238568579556 1.0107449196998175 1.3096032260476331 0.563776669799907 0.08004918375173248 0.8136191540437343 0.5320585900610516 0.05997021670801823 0.1316776760176819 6.255431271886921e-07 6.203742743117802 0.2988583063478156 TPAPPEPGS(ph)PAPGEGPSGR ddPTM_PC-9_Lapatinib_30min_R1 4 TPAPPEPGSPAPGEGPSGR 19 0 P0C1Z6-2;P0C1Z6 P0C1Z6-2 TFPT TCF3 fusion partner 1 T(0.001)PAPPEPGS(0.999)PAPGEGPSGR;TPAPPEPGS(0.995)PAPGEGPS(0.005)GR;TPAPPEPGS(1)PAPGEGPSGR;T(0.002)PAPPEPGS(0.966)PAPGEGPS(0.032)GR 132.62 2.8057e-05 103522000.0 53993.4 62321.0 60988.0 52841.5 69601.0 67906.0 59886.2 67080.0 59520.1 52269.2 True False 53223.444214823096 62176.699553490806 55973.80206048809 56727.640184076554 65507.20602083096 65001.818676617564 62986.814410572915 70196.78168757977 52816.31956356084 61303.861575668925 0.868190728069031 1.0142378955483011 0.9130550771487403 0.9253518249263332 1.0685657369230117 1.0603217645006613 1.0274526398769623 1.1450629680307185 0.8615496349829171 1.0 15.903690332757526 -6.253323112448221 24.609468481708014 1.0360847807148428 0.9349856751836316 0.27953367385733097 0.07528218635035956 622.5699462354827 1887702.4061662026 0.02125207302812686 0.026940491691463557 5.580548508407318e-07 6.253323112448221 -0.10109910553121115 TPAPSPGPGSCGSAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 TPAPSPGPGSCGSASPR 17 0 M0QXP1;Q10586 M0QXP1 DBP D site-binding protein 1 TPAPSPGPGS(0.019)CGS(0.046)AS(0.935)PR;TPAPSPGPGS(0.004)CGS(0.232)AS(0.763)PR 159.64 2.7016e-05 7367500.0 10729.099999999999 8841.6 10217.8 16747.4 13792.5 10719.099999999999 8056.7 11789.7 14213.7 12535.099999999999 True False 14140.730620856437 11699.474293088391 10082.305295808083 12886.545674750696 11877.649450879848 10048.83298249276 8773.730692104 9967.872765354175 14965.00716415634 12096.249964387493 1.1690177255337886 0.9671984563424825 0.8335066921972798 1.0653339433865792 0.9819282410539444 0.8307395277112724 0.7253265034977531 0.8240465263780542 1.2371608728502421 1.0 13.56227223727135 -6.6085947401889005 8.789522127989956 0.9002866740506923 0.9970233927060762 0.0554967745882623 0.15052186080697094 0.7845930540731902 72.32507978688335 0.051136011498358364 0.05111094920299708 2.462664555895323e-07 6.6085947401889005 0.09673671865538391 TPAPSPGPGSCGSAS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TPAPSPGPGSCGSASPR 17 0 M0QXP1;Q10586 M0QXP1 DBP D site-binding protein 1 TPAPSPGPGS(0.023)CGS(0.303)AS(0.674)PR;TPAPSPGPGS(0.131)CGS(0.227)AS(0.642)PR;T(0.003)PAPS(0.002)PGPGS(0.135)CGS(0.053)AS(0.807)PR 130.95 2.6484000000000003e-05 3282900.0 19391.6 19425.6 21709.9 21002.5 34919.2 26868.3 20699.1 22963.5 26077.6 23596.199999999997 True False 22674.21487844184 21354.045188682056 22227.546351254252 19825.79801602371 28077.03342957459 25459.27904906108 18738.33139949351 22360.732456839443 26458.935566027772 27874.004272583574 0.8134538065183492 0.7660917670765214 0.7974292510644735 0.7112647979150971 1.007283817387899 0.9133699916270164 0.6722511490006562 0.802207398627441 0.9492333899099082 1.0 14.766632648917328 -14.522878745156806 0.15187977023706015 1.6596950472965804 0.7676224015413641 0.26902744279317936 0.09555516449146963 202.94078849870903 1.8129838796034412 40.06738780171976 0.4967624611075112 3.000000000853326e-15 14.522878745156806 -0.8920726457552163 TPAPSPGPGSCGSAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 TPAPSPGPGSCGSASPR 17 0 M0QXP1;Q10586 M0QXP1 DBP D site-binding protein 1 TPAPSPGPGS(0.005)CGS(0.032)AS(0.964)PR;TPAPSPGPGS(0.001)CGS(0.032)AS(0.967)PR 140.75 6.2979e-08 2943900.0 12105.0 13936.8 7718.8 12471.0 13501.8 8360.5 10877.599999999999 12413.8 14090.7 10845.4 True False 11932.380480214875 13904.530195874442 7084.190059429649 13388.15894203644 12707.650669560135 8002.940904277387 11440.788903494433 12990.590466804944 12503.65698435095 12720.01293941288 0.9380792721713725 1.0931223310938107 0.5569326142333811 1.0525271480309044 0.9990281244278895 0.6291613807624618 0.8994321749504846 1.021271796552477 0.9829909013385079 1.0 13.634812517751694 -7.698787173057054 6.061547013242376 1.0013644369045864 0.8773856151810281 0.10469038298335909 0.16154506531886997 0.47513672303886684 33.24690823256501 0.07887483709338809 0.04430270009947629 2.0008421464078408e-08 7.698787173057054 -0.12397882172355834 TPAQFDADELR ddPTM_PC-9_AZD4547_30min_R2 1 TPAQFDADELR 11 0 P04083;Q5T3N1 P04083;Q5T3N1 ANXA1 Annexin A1;Annexin 0 124.39 0.0023689 26221000.0 18955.0 28718.0 27324.0 42384.0 31055.0 24162.0 26978.0 28900.0 24451.0 26063.0 False True 24982.295711507384 38000.531888901605 26961.665906815557 32613.02362627233 26743.549298319667 22651.14632039909 29378.98973668895 24434.16905593321 25743.429942294177 25150.5423029598 0.993310418939451 1.5109229626603151 1.0720113141911305 1.2967125413607612 1.063338872624325 0.9006225809187991 1.1681254973667718 0.9715165884537494 1.0235735528957006 1.0 14.61830188770573 -6.39090971851941 5.272302468970708 1.0170368290706198 1.2277284138078646 0.3171869188439095 0.14259914137583432 0.2596361073117038 10.061607742044304 0.041940123103787086 0.04756760947240338 4.0652782970884644e-07 6.39090971851941 0.2106915847372448 TPAQFDADELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TPAQFDADELR 11 0 P04083;Q5T3N1 P04083;Q5T3N1 ANXA1 Annexin A1;Annexin 0 ;;; 119.74 0.0043075000000000006 39821100.0 56718.8 62505.0 69157.0 74502.0 79980.0 66111.0 67466.0 66388.0 71602.0 57818.0 False True 66320.17259263645 68710.08331884597 70805.96515938311 70327.89447874294 64308.493141233994 62644.02277823596 61075.132068458544 64645.38534390032 72649.04379232445 68299.9457129639 0.9710135476732644 1.0060049477580215 1.036691382698179 1.0296918064078946 0.9415599451791028 0.9171899351355648 0.8942193354754888 0.9464924850098392 1.063676450017076 1.0 16.059596811363953 -6.265244083389609 24.973779375453795 0.9523658089846676 1.012350099686235 0.204408407660152 0.04697967366623871 466.0325279964472 3058991.296802569 0.015115907911431564 0.017820507808982658 5.429450982160161e-07 6.265244083389609 0.0599842907015673 TPAQFDADELR ddPTM_PC-9_Lapatinib_30min_R1 3 TPAQFDADELR 11 0 P04083;Q5T3N1 P04083;Q5T3N1 ANXA1 Annexin A1;Annexin 0 ;; 134.98 0.00030859 85648000.0 61019.0 66480.0 74547.0 60728.0 58338.0 66038.0 61168.0 57716.0 65453.0 51838.0 False True 60148.857870485845 66326.06964451901 68418.03341974152 65194.13970266934 54906.67353692094 63213.70868209688 64334.97974267741 60397.69606261693 58080.99388935418 60798.12923020683 0.9893208661525986 1.0909228702314362 1.1253312278850323 1.072305028594176 0.9030980760776635 1.0397311476927797 1.0581736733885116 0.9934137255099792 0.9553088988879171 1.0 15.891739311905376 -6.0554010335564294 24.999631340298652 0.9961771519189274 1.0754405748786273 0.3525256382380001 0.05122702542677799 339.5368016037591 153214.67560531702 0.015567283137225862 0.02009737137155135 8.802356757585463e-07 6.0554010335564294 0.0792634229596999 TPAQYDASELK ddPTM_PC-9_AZD4547_30min_R2 2 TPAQYDASELK 11 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YNP5;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YMW4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ; 134.3 0.00027784 16292500.0 59548.0 57196.0 61313.0 65769.0 73596.0 66442.0 67569.0 78817.0 67344.0 65682.0 False True 78483.02532465536 75683.488471259 60499.94955879748 50606.97317092071 63378.46575943107 62287.371236650826 73582.51010150248 66637.64368448046 70903.66635449912 63382.49317204488 1.2382445277376788 1.1940755985382967 0.9545214542851281 0.7984377173923025 0.9999364585958637 0.9827220123319942 1.160927985299833 1.0513572494474117 1.118663258670479 1.0 15.95179678928856 -5.183763268016374 5.533401209815311 1.0071155947584796 1.2236552801941447 0.44759719228050543 0.09257643259801153 0.22123102797319427 11.739744731779863 0.02646611311498287 0.07302370686057243 6.549931105972276e-06 5.183763268016374 0.21653968543566515 TPAQYDASELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPAQYDASELK 11 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YNP5;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YMW4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ; 156.51 0.00042327 12182200.0 40910.0 46186.0 43254.0 48497.0 46722.0 38999.0 44407.0 39699.0 38909.0 37793.0 False True 47835.254990668946 50771.04084735966 44285.33940170849 45779.8703193954 37567.15949668334 36953.82378618421 40200.44748116144 38656.94331456742 39477.97051640387 44644.57173077663 1.0714685601450793 1.1372276377412223 0.9919535048687566 1.0254297117119868 0.841472054502556 0.8277338622269581 0.9004554399935806 0.8658822745054687 0.8842725775144783 1.0 15.44619715034566 -5.901158399752546 1.6804866848156943 0.8786866872627764 1.0926698821193817 0.6848600015536009 0.056172622060029244 0.1904074764637515 1.0941326860491813 0.01770999404112195 0.032629134170016956 1.2555719367895158e-06 5.901158399752546 0.21398319485660522 TPAQYDASELK ddPTM_PC-9_Lapatinib_30min_R1 4 TPAQYDASELK 11 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YKS4;H0YNP5;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YMW4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ;;; 145.91 0.00059431 134294000.0 162683.0 175277.0 181598.0 161715.0 153179.0 125519.0 169076.0 149425.0 151932.0 169838.0 False True 160363.11058759136 174871.15687548698 166667.71342855186 173608.06056542555 144169.3123815009 120150.84496908014 177829.92798477833 156367.83100278152 134819.8182451125 199194.27200509005 0.805058845183528 0.8778924971849514 0.8367093679495611 0.8715514699187199 0.7237623398017033 0.6031842369744944 0.8927461929238317 0.7850016440170821 0.6768257786130889 1.0 17.603816636558342 -6.252697282700508 24.601497564160887 0.766274632440306 0.8491598873706371 0.08103697520837239 0.10526492322633084 1138.3538617913498 3203485.0171417603 0.030502951488014025 0.03872460751314089 5.588596022231995e-07 6.252697282700508 0.08288525493033105 TPARPFGS(ph)VGR ddPTM_PC-9_Lapatinib_30min_R1 1 TPARPFGSVGR 11 1 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 T(0.042)PARPFGS(0.958)VGR 72.2 0.013129 16022000.0 26036.0 30060.0 31705.0 30290.0 27663.0 35140.0 36090.0 34021.0 28010.0 25164.0 True False 25664.721865582345 29990.39791688091 29098.33728483922 32517.62764447789 26035.916727550535 33637.14411534091 37958.56361027379 35601.739859766625 24855.21884162392 29513.56387107765 0.8695907406402028 1.016156437354912 0.9859309913214059 1.1017858699316256 0.8821678344669484 1.1397181398449896 1.2861396128263578 1.2062839992921082 0.8421625714263955 1.0 14.849090521555741 -6.784264022375029 24.99942265310726 1.1197085841531302 0.9817093649890535 0.17341354659938524 0.12847522289233324 384.06218372054605 420653.53561951197 0.04568997105794497 0.04032177828017601 1.6433723575654334e-07 6.784264022375029 -0.13799921916407676 TPAS(ph)KSPSEGQTATTSPR ddPTM_PC-9_Lapatinib_30min_R1 1 TPASKSPSEGQTATTSPR 18 1 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 T(0.282)PAS(0.431)KS(0.282)PS(0.004)EGQTATTSPR 51.466 0.029167000000000002 4217700.0 8895.6 11424.0 12101.0 8946.3 10695.0 8035.5 9951.7 8317.7 9597.2 6400.3 True False 8768.747112746754 11397.548429888462 11106.102491210828 9604.24074598193 10065.941127179014 7691.84039666539 10466.950331957934 8704.170707256722 8516.262273003682 7506.583327136318 1.1681409145286792 1.5183403598127387 1.4795149813447404 1.2794423677763722 1.3409484299988532 1.024679279700975 1.3943694322448779 1.1595382783257895 1.1345057933637228 1.0 12.873940689257816 -7.68244769408419 0.3475576940274492 0.9897524010191854 1.4212693621647905 0.40296338336832493 0.13297244313583279 1.3090952418764994 0.47307756773693616 0.18495957596675097 0.19119392220369125 2.077553928653028e-08 7.68244769408419 0.4315169611456051 TPAS(ph)PHFR ddPTM_PC-9_AZD4547_30min_R2 2 TPASPHFR 8 0 P29590-2 P29590-2 PML Protein PML 1 TPAS(1)PHFR;TPAS(1)PHFR 112.71 0.0021114000000000003 27618600.0 20721.1 25801.6 31451.0 37303.0 37574.0 39199.0 26968.0 35549.0 29622.0 31638.0 True False 27309.978774345294 34141.462622212006 31033.939190281653 28703.36967560489 32357.498674450577 36747.88033330535 29368.09975606151 30055.718884753267 31187.75844548843 30530.36324985772 0.8945186321840624 1.1182789520976666 1.016494266258895 0.940158144883476 1.0598465013219707 1.2036502819361838 0.9619308986177351 0.9844533665970494 1.0215325048788528 1.0 14.897957134362754 -1.5480883385139732 22.784878485361467 1.0246500849455735 0.005121555379785425 0.0 0.08506035611096621 0.0 0.0 0.019439863988766338 0.0 0.028308161295718302 1.5480883385139732 -1.019528529565788 TPAS(ph)PHFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPASPHFR 8 0 P29590-2 P29590-2 PML Protein PML 1 T(0.005)PAS(0.995)PHFR;TPAS(1)PHFR 85.958 0.007274299999999999 22827000.0 15540.3 19722.2 21582.7 22304.0 27058.0 21079.9 20766.3 24007.7 21747.0 15845.7 True False 18170.96585508415 21680.08967652096 22097.313420845567 21054.379190543637 21756.17913747823 19974.432934956916 18799.16572900765 23377.52331326079 22065.008733718052 18718.399975507815 0.9707542246591611 1.1582234435041663 1.180512941798386 1.1247958809562968 1.1622883988986885 1.0671015130081931 1.0043147786993287 1.2489060680319488 1.1787871165585266 1.0 14.192169500044772 -10.602244925056368 4.693422793680867 0.9999940534413236 1.1245057683319757 0.1684616306293445 0.08093445216323057 9535315.855679844 21555839.056809288 341.067610378439 0.01984771734892337 2.4989356625116347e-11 10.602244925056368 0.12451171489065205 TPAS(ph)PHFR ddPTM_PC-9_Lapatinib_30min_R1 3 TPASPHFR 8 0 P29590-2 P29590-2 PML Protein PML 1 T(0.017)PAS(0.983)PHFR;T(0.001)PAS(0.999)PHFR;T(0.008)PAS(0.992)PHFR 97.81299999999999 0.0032290999999999995 56242200.0 59719.0 40171.0 52700.0 42801.2 45133.0 50949.0 43574.0 43293.0 49342.0 39122.0 True False 58867.39610887668 40077.986517598896 48367.20942788288 45948.94302861763 42478.365674892026 48770.03003791985 45830.04851078056 45304.55082886679 43784.58436570535 45884.185573211755 1.2829561072833953 0.8734596902379662 1.054115025114901 1.001411324067255 0.9257735567108305 1.0628940980134323 0.9988201367910341 0.9873674396286252 0.9542412885555889 1.0 15.485709380107417 -4.747268484772617 24.99995703447613 0.9876446700862597 1.282956856831936 0.737626099404463 0.053413472037680515 366.19591488814604 645997.4189939849 0.01263263248020063 0.2620911950297897 1.7894992274165167e-05 4.747268484772617 0.2953121867456764 TPASKS(ph)PSEGQTATTSPR ddPTM_PC-9_AZD4547_30min_R2 1 TPASKSPSEGQTATTSPR 18 1 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 T(0.052)PAS(0.176)KS(0.652)PS(0.119)EGQTATTSPR 72.48899999999999 0.0037673999999999997 3444600.0 11395.0 12075.0 11864.0 16354.0 17832.0 13522.0 15701.0 14728.0 13893.0 15670.0 True False 15018.372969276003 15978.007610505147 11706.67560820011 12583.83796678128 15356.334602725372 12676.467202401982 17098.358583132678 12452.126015771079 14627.355616878362 15121.398069576784 0.9931868005969593 1.0566488321375391 0.7741794478483534 0.8321874676455413 1.0155366939001007 0.8383131734297878 1.1307392679208281 0.8234771651719097 0.9673282556000955 1.0 13.884303911621707 TPASKS(ph)PSEGQTATTSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPASKSPSEGQTATTSPR 18 1 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 T(0.026)PAS(0.102)KS(0.842)PS(0.026)EGQT(0.002)AT(0.001)T(0.001)SPR 55.851000000000006 0.018207 3103900.0 11084.0 12922.0 14208.0 14074.0 15161.0 13925.0 14366.0 10990.0 13708.0 10833.0 True False 12960.302281021128 14204.810761477098 14546.772604140051 13285.479408523643 12190.310884149134 13194.748486438504 13005.14847916691 10701.524144867524 13908.45356701186 12796.937146019185 1.0127659558797444 1.1100164515456628 1.1367386147290093 1.0381764993396432 0.9525959801983744 1.0310864495058545 1.0162704036733112 0.8362566778876855 1.0868580042481837 1.0 13.643510932508594 -6.010029678198727 5.736607122831742 0.9833759486179421 1.0891661118093467 0.30415740002870717 0.067450507904636 0.1855418886271546 22.33410038032121 0.01922593162469304 0.026824179566646348 9.771704421900027e-07 6.010029678198727 0.10579016319140466 TPASKS(ph)PSEGQTATTSPR ddPTM_PC-9_Lapatinib_30min_R1 1 TPASKSPSEGQTATTSPR 18 1 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 T(0.003)PAS(0.173)KS(0.782)PS(0.015)EGQT(0.003)AT(0.011)T(0.011)S(0.002)PR 58.658 0.014621 6036800.0 6356.9 6299.2 5878.7 8365.6 9211.2 10075.0 6724.1 8472.6 8367.8 6442.7 True False 6266.249440287316 6284.614589421694 5395.375978438237 8980.834130823512 8669.415325915968 9644.115735972102 7072.240996726014 8866.26792674698 7425.3302471596035 7556.312110641874 0.8292735065115021 0.8317039446492431 0.7140223828022801 1.1885208021219007 1.1473077341136377 1.2762992839310974 0.9359381789915583 1.1733591462242856 0.982665900830406 1.0 12.883466577597446 -5.761808627979913 24.999998086404155 1.1102157429602475 0.7956703123882911 0.6512132386770535 0.10342222323588623 5.696788619771252 385752.0242774431 0.0281217393333612 0.044813081410819904 1.7305787713839426e-06 5.761808627979913 -0.3145454305719564 TPASKSPS(ph)EGQTATTSPR ddPTM_PC-9_AZD4547_30min_R2 1 TPASKSPSEGQTATTSPR 18 1 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 T(0.001)PAS(0.001)KS(0.269)PS(0.509)EGQT(0.137)AT(0.039)T(0.039)S(0.005)PR 57.985 0.015481 7389100.0 7395.9 7905.5 9647.9 8898.2 9354.7 8551.9 9715.8 12166.0 7828.8 5786.7 True False 9747.642355723416 10460.798274521618 9519.962542174124 6846.857465819572 8055.961378875892 8017.148341090184 10580.487378001424 10286.024246867939 8242.61438518803 5584.109394334399 1.7456037601292893 1.8733154270106303 1.7048309533178228 1.2261324021994175 1.4426582307018228 1.4357076079534419 1.8947493021423105 1.8420169664484136 1.4760839738474558 1.0 12.44711148930382 -5.53372267937173 24.970550815170412 1.5191592428752425 1.8043630587170099 0.22665995344132217 0.24971487629120465 340.22877252781274 783449.1560854325 0.07027811002337091 0.12186571268375909 2.9260202043394773e-06 5.53372267937173 0.28520381584176735 TPAST(ph)PVSGTPQAS(ph)PMIER ddPTM_PC-9_AZD4547_30min_R2 1 TPASTPVSGTPQASPMIER 19 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 2 T(0.207)PAS(0.3)T(0.406)PVS(0.005)GT(0.083)PQAS(1)PMIER 120.15 0.00045898 8024600.0 8263.1 8772.4 14710.0 18863.0 12958.0 13915.0 15309.0 16867.0 15340.0 13699.0 True False 10890.593916842863 11607.906746368151 14514.935788656747 14514.42678044487 11159.005371361332 13044.892850275373 16671.4713425373 14260.592715101231 16150.841082769306 13219.402179651079 0.8238340712265338 0.8780961944131227 1.0980024354656455 1.0979639308339715 0.8441384277224456 0.9867989999090631 1.261136556401928 1.078762301146483 1.2217527588071007 1.0 13.690369314946173 -7.113968259570341 6.979688167018564 1.1461446539998756 0.9568014520093652 0.4071691953570793 0.11015884984749218 0.272088625123907 14.901480575669144 0.04334078609006295 0.033555282765245574 7.691866542699156e-08 7.113968259570341 -0.18934320199051047 TPAST(ph)PVSGTPQAS(ph)PMIER ddPTM_PC-9_Lapatinib_30min_R1 2 TPASTPVSGTPQASPMIER 19 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 2 T(0.026)PAS(0.168)T(0.806)PVS(0.038)GT(0.065)PQAS(0.897)PMIER;TPAS(0.11)T(0.71)PVS(0.032)GT(0.147)PQAS(1)PMIER 163.04 1.9123e-05 10666900.0 40002.0 33260.9 34672.2 23483.4 26666.0 29689.6 28397.5 23434.0 34300.0 21410.0 True False 39431.564144531614 33183.88642959362 31821.58555456245 25210.447574325925 25097.558307373132 28419.845017837913 29867.783599965354 24522.82919002298 30436.7728049875 25110.689972968234 1.5703098635274404 1.3215043658822685 1.2672525362233584 1.0039727144680246 0.9994770487943885 1.1317827207628304 1.1894449587852087 0.9765892222165904 1.2121042009499865 1.0 14.616014050010865 -5.003720239953378 1.3048442957894855 1.0789125384059306 1.655613149789505 0.7566411807662432 0.08812887143144678 0.44908418055194876 0.8949162649503618 0.026574461104394473 0.31152308650085625 9.914704160279565e-06 5.003720239953378 0.5767006113835744 TPASTPVS(ph)GTPQAS(ph)PMIER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPASTPVSGTPQASPMIER 19 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 2 T(0.117)PAS(0.023)T(0.037)PVS(0.625)GT(0.221)PQAS(0.978)PMIER 108.25 0.0012758 0.0 5771.2 7755.9 10053.0 10604.0 12353.0 9282.7 12223.0 11795.0 11120.0 9765.8 True False 6748.150173604223 8525.854495042588 10292.701646214804 10009.892258631851 9932.518326752474 8795.898870740586 11065.148953143342 11485.393747835522 11282.608963026842 11536.262233969737 0.584951177144152 0.7390482568901141 0.8922042024934959 0.8676893828883909 0.8609823637248059 0.7624565645569443 0.9591623984205948 0.9955905574004353 0.9780125255651707 1.0 13.493888243913826 -3.6494551661064367 0.3348878514505137 0.9822071433024783 3.627959951398433e-31 0.7456119383797497 0.06429018201746613 8.720226271875223 0.43460608769908166 0.06816654532221161 4.020183097430897 0.0002241531435769656 3.6494551661064367 -0.9822071433024783 TPASTPVS(ph)GTPQAS(ph)PMIER ddPTM_PC-9_Lapatinib_30min_R1 1 TPASTPVSGTPQASPMIER 19 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 2 T(0.001)PAS(0.13)T(0.178)PVS(0.408)GT(0.305)PQAS(0.977)PMIER 124.2 9.2321e-05 9219400.0 11731.0 9688.6 12179.0 10261.0 14231.0 11417.0 13000.0 12867.0 16209.0 12276.0 True False 11563.713788798066 9666.166641965809 11177.68963229954 11015.62816969256 13393.960559222496 10928.721524326897 13673.07639051148 13464.847793292885 14383.371731663054 14397.890243258207 0.8031533504856907 0.6713599338967026 0.7763421892685616 0.765086271917555 0.93027244498507 0.7590502038619342 0.9496583290676132 0.9351958909117106 0.9989916222898038 1.0 13.813569805204478 -7.017972959264909 0.5417264997003128 1.0128845691891417 0.7245592315044972 0.7098525219101122 0.05963084998921163 0.47838782038897987 0.2991287275007248 0.052227599573511994 0.05166814321522665 9.594603691066005e-08 7.017972959264909 -0.2883253376846445 TPASTPVS(ph)GTPQASPMIER ddPTM_PC-9_AZD4547_30min_R2 1 TPASTPVSGTPQASPMIER 19 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 TPASTPVS(0.476)GT(0.321)PQAS(0.203)PMIER 115.53 7.3156e-05 21693000.0 3004.9 7646.2 10207.0 11509.0 11147.0 13161.0 7053.6 12416.0 11247.0 8290.7 True False 3960.3956941972283 10117.684620409476 10071.648510864678 8855.77786227747 9599.431461225866 12338.040589469929 7681.356735366195 10497.392491296421 11841.49345879443 8000.445116492684 0.49502191897210673 1.2646402135241406 1.2588860199918461 1.1069106447616948 1.199862172847973 1.5421692680617756 0.9601161714779222 1.3121010566845028 1.4801043299932821 1.0 12.965864553348627 -4.760399328483629 24.945684353719994 1.2423255119194911 0.49502100968234375 0.6139343720440729 0.1762356347458275 16.262189794493086 389857.84063666407 0.04220008618733983 0.2507468767717367 1.7362036764584155e-05 4.760399328483629 -0.7473045022371474 TPASTPVS(ph)GTPQASPMIER ddPTM_PC-9_Lapatinib_30min_R1 2 TPASTPVSGTPQASPMIER 19 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 TPASTPVS(0.54)GT(0.408)PQAS(0.051)PMIER;TPAST(0.009)PVS(0.944)GT(0.023)PQAS(0.024)PMIER 172.95 1.8739e-08 56341000.0 27543.4 27540.0 39122.0 28027.8 38144.0 43935.0 32529.2 33847.0 47588.0 38506.4 True False 27150.62606515904 27476.232822052563 35905.54017528718 30089.057909999916 35900.44491398938 42056.00246748728 34213.402809401996 35419.65518454839 42228.1383161442 45162.179933447216 0.6011805919282303 0.6083903138099762 0.7950355857090824 0.6662445868277472 0.7949227642884754 0.931221710941825 0.7575675678149334 0.7842769157012395 0.9350332153667795 1.0 15.46282750479389 -3.4522449947185545 0.1596525150020914 1.0259266514668182 3.944985496448026e-18 0.7183138839250783 0.06921938389862946 20.317730281409336 0.36740620624885695 0.24972206387504456 4.427307846063062 0.00035298398786970744 3.4522449947185545 -1.0259266514668182 TPASTPVSGT(ph)PQAS(ph)PMIER ddPTM_PC-9_AZD4547_30min_R2 3 TPASTPVSGTPQASPMIER 19 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 2 TPAS(0.002)T(0.004)PVS(0.165)GT(0.887)PQAS(0.943)PMIER;T(0.004)PAS(0.003)T(0.017)PVS(0.574)GT(0.664)PQAS(0.738)PMIER;T(0.008)PAS(0.004)T(0.002)PVS(0.24)GT(0.746)PQAS(1)PMIER 138.28 0.00042439999999999996 24940500.0 35021.4 35406.4 52006.1 63852.1 62353.9 59335.4 53252.7 64615.7 58519.5 56145.8 True False 46157.47670962722 46850.826390110975 51316.4651338179 49131.98485011097 53697.13729165974 55625.14805808329 57992.08713585053 54630.82828607142 61612.72130007296 54180.15263145149 0.851925926152391 0.8647230418268358 0.9471450824970319 0.9068262539664742 0.9910850133059359 1.0266701985219764 1.070356658651903 1.0083180949615544 1.1371824977899172 1.0 15.725476837325774 -6.157324938584262 0.7684783523429152 1.0624079129798398 0.8513330690511572 0.7768924742284414 0.04021779009292012 0.32715046796802133 0.40515131195022624 0.021094491452905362 0.04214529821281756 6.961054939680922e-07 6.157324938584262 -0.2110748439286826 TPASTPVSGT(ph)PQAS(ph)PMIER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPASTPVSGTPQASPMIER 19 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 2 TPASTPVS(0.184)GT(0.902)PQAS(0.913)PMIER 115.63 0.0007252000000000001 4418200.0 5807.3 10044.0 8342.1 8391.4 8917.3 8607.3 10653.0 9399.7 8147.1 9586.1 True False 6790.361190596716 11041.101941516481 8541.007301590425 7921.257063285865 7170.019078373662 8155.91803571433 9643.870718959013 9152.967834805399 8266.235924701079 11323.98404647416 0.5996441855383015 0.9750192066858522 0.7542404922629468 0.6995114997316012 0.6331710684991756 0.7202339743894076 0.8516323123893603 0.8082815904050369 0.7299759422810965 1.0 13.467094001400552 -9.80757615106605 9.70204435047401 0.9999993421235044 0.7575653225334349 0.34420604231538054 0.10230153976483329 0.0 0.0 0.09963732349970882 0.02416560053194919 1.557484914770339e-10 9.80757615106605 -0.2424340195900695 TPASTPVSGT(ph)PQAS(ph)PMIER ddPTM_PC-9_Lapatinib_30min_R1 4 TPASTPVSGTPQASPMIER 19 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 2 TPAST(0.002)PVS(0.46)GT(0.558)PQAS(0.98)PMIER;TPAST(0.006)PVS(0.171)GT(0.823)PQAS(1)PMIER;T(0.001)PAST(0.008)PVS(0.158)GT(0.843)PQAS(0.99)PMIER;T(0.007)PAS(0.001)T(0.057)PVS(0.061)GT(0.874)PQAS(1)PMIER 168.17 6.667199999999999e-07 28584100.0 67206.9 75453.8 70856.1 68852.8 79425.7 73230.1 69045.5 74155.5 88295.3 66694.2 True False 66248.51728176406 75279.09136196751 65030.58497045567 73916.46459820759 74754.03648293435 70098.21933070071 72620.33814777386 77601.03524796217 78350.55352327159 78222.20360556476 0.8469272690887362 0.96237497656755 0.8313571079941983 0.9449550279985865 0.9556626256642086 0.8961422217682691 0.9283852256830005 0.9920589253566054 1.001640837406653 1.0 16.25529055849988 -7.7206712704793885 3.1871604918660137 1.000524276505331 0.9094120858662571 0.5066178986784222 0.040497221027378405 0.20789947857137547 4.289301089631186 0.02246331168393313 0.010958112002764206 1.9025178034603166e-08 7.7206712704793885 -0.09111219063907394 TPASTPVSGT(ph)PQASPMIER ddPTM_PC-9_AZD4547_30min_R2 2 TPASTPVSGTPQASPMIER 19 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 TPAST(0.002)PVS(0.022)GT(0.879)PQAS(0.097)PMIER;TPAST(0.001)PVS(0.003)GT(0.932)PQAS(0.064)PMIER 174.04 5.6175e-08 139783000.0 27425.0 23263.4 35062.0 35829.0 37730.0 35964.0 26912.0 34261.0 27174.0 31282.0 True False 36145.57952456287 30782.839109418284 34597.05497089616 27569.17760253188 32491.840767206573 33715.165394703814 29307.11586454788 28966.749689457705 28610.36216317948 30186.826701499747 1.197395800558496 1.0197441226205113 1.1460977767887508 0.9132850522894539 1.076358276691346 1.116883391821664 0.9708577901993202 0.9595824687335742 0.9477764074406024 1.0 14.881631485436076 -1.5228787452803376 0.33771033192308897 0.9809986264660597 2.8889656417047878 0.374673899930105 0.0710873223778588 69.95405509781709 0.9924669534638826 0.06371487486946355 83.9624880660392 0.029999999999999995 1.5228787452803376 1.907967015238728 TPASTPVSGT(ph)PQASPMIER ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 TPASTPVSGTPQASPMIER 19 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 T(0.022)PAS(0.016)T(0.072)PVS(0.06)GT(0.82)PQAS(0.01)PMIER;TPAS(0.011)T(0.008)PVS(0.02)GT(0.953)PQAS(0.008)PMIER;TPAST(0.001)PVS(0.02)GT(0.978)PQASPMIER;TPASTPVS(0.177)GT(0.821)PQAS(0.002)PMIER;TPAST(0.001)PVS(0.177)GT(0.821)PQAS(0.001)PMIER;TPAST(0.001)PVS(0.414)GT(0.529)PQAS(0.056)PMIER 174.7 5.2118000000000004e-08 248604000.0 72928.6 77168.59999999999 84098.8 85152.4 105448.1 94262.5 94511.1 82298.4 80901.3 68219.5 True False 85273.97157449275 84829.3886184896 86104.03433847496 80381.58709580544 84786.30177051968 89319.20856035253 85558.32440689078 80138.15420236267 82084.32846227715 80587.1553247352 1.058158353286842 1.0526415565440899 1.0684585402165998 0.9974491191790876 1.0521068950611738 1.1083553973388256 1.0616868663762071 0.9944283785602901 1.018578309800227 1.0 16.298262287458535 -7.757731346482169 24.99950593813129 1.0048775021252827 1.0567531465130942 0.4647150885456258 0.0258887488958472 91.29780444513486 615542.3955705467 0.01369647755038877 0.007506065398761257 1.7469024483883655e-08 7.757731346482169 0.05187564438781145 TPASTPVSGT(ph)PQASPMIER ddPTM_PC-9_Lapatinib_30min_R1 4 TPASTPVSGTPQASPMIER 19 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 TPASTPVS(0.014)GT(0.984)PQAS(0.002)PMIER;TPAST(0.001)PVS(0.018)GT(0.978)PQAS(0.003)PMIER;TPASTPVS(0.081)GT(0.546)PQAS(0.372)PMIER;TPASTPVS(0.157)GT(0.6)PQAS(0.242)PMIER 172.99 7.0105e-08 185973600.0 70193.8 69374.9 78615.0 66674.0 79916.0 90059.0 81451.0 73293.0 95354.0 70396.0 True False 69192.82354003357 69214.26668143108 72151.57816267593 71577.4283779438 75215.49800090113 86207.3865077828 85668.13423719611 76698.46034925111 84614.22839786539 82563.85480322629 0.8380522409587127 0.8383119568046917 0.8738881964103317 0.8669341874665815 0.910997895872977 1.044129864251616 1.0375985283314135 0.9289592949850255 1.0248337919725978 1.0 16.333222709512057 -6.55542099192195 3.5922896875161276 1.0042393761009203 0.8563318769157778 0.8357079356412027 0.03202866848765078 0.09682481647739867 2.652854404766339 0.011490346474332893 0.011916000960496314 2.7834216957272326e-07 6.55542099192195 -0.14790749918514245 TPASTPVSGTPQAS(ph)PMIER ddPTM_PC-9_AZD4547_30min_R2 3 TPASTPVSGTPQASPMIER 19 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 TPASTPVS(0.006)GT(0.358)PQAS(0.636)PMIER;T(0.119)PAS(0.02)T(0.005)PVS(0.02)GT(0.113)PQAS(0.722)PMIER;TPASTPVS(0.029)GT(0.124)PQAS(0.847)PMIER 131.31 4.007e-05 155470000.0 157277.0 155326.0 188500.0 245168.0 244041.0 234311.0 180669.0 233818.0 185115.0 215776.0 True False 207287.8144351754 205532.09193451947 186000.3668362881 188648.3054078413 210160.11960429035 219659.49612941896 196748.19099777032 197686.80070312112 194899.80098023725 208221.74791710326 0.9955147169242874 0.9870827326660682 0.8932802106259242 0.9059971270769733 1.0093091701831203 1.0549306128045244 0.9448974132908501 0.949405154267669 0.9360203865824347 1.0 17.667761234589847 -5.0247697249681424 24.921695326640823 0.9608807563726276 0.9934067860973859 0.06263955037522229 0.046165665368692294 1984.732227494563 1996917.2624502298 0.012892728648275675 0.03447912081775638 9.445615763907947e-06 5.0247697249681424 0.032526029724758265 TPASTPVSGTPQAS(ph)PMIER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPASTPVSGTPQASPMIER 19 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 TPAS(0.004)T(0.02)PVS(0.06)GT(0.024)PQAS(0.892)PMIER 65.887 0.010262 5864000.0 2859.4 6491.1 3104.6 8024.3 11086.0 6639.2 7047.2 6700.5 5946.8 3088.6 True False 3343.439944275697 7135.493509814581 3178.625438261066 7574.724486131605 8913.777881516879 6291.028664356373 6379.638198690313 6524.618974766593 6033.76069975971 3648.538730655853 0.9163778134471626 1.955712693923334 0.8712050694579535 2.076098143754661 2.4431090196799303 1.7242598006423004 1.7485461083603528 1.788282777415862 1.6537471972169786 1.0 11.83310305327155 -5.7760650389310015 24.999881276451305 1.8335969431852377 1.3185597900194532 0.21985727465431437 0.44120567586513965 337.41380877869636 576746.2265754751 0.12045299503752381 0.17953092693758432 1.6746920592602715e-06 5.7760650389310015 -0.5150371531657845 TPASTPVSGTPQAS(ph)PMIER ddPTM_PC-9_Lapatinib_30min_R1 2 TPASTPVSGTPQASPMIER 19 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 TPAST(0.001)PVS(0.178)GT(0.178)PQAS(0.643)PMIER;TPAS(0.066)T(0.013)PVS(0.291)GT(0.026)PQAS(0.604)PMIER 191.71 1.3174e-11 52458900.0 31796.0 23673.0 35828.0 28372.0 29430.0 37429.0 36523.0 30690.0 43570.0 38370.0 True False 31342.583209327706 23618.186622964782 32882.36014007948 30458.57152621745 27698.985261606194 35828.24892126053 38413.98223158851 32115.969439353285 38662.68778755992 45002.20337518875 0.6964677473238553 0.5248228942493579 0.7306833371231918 0.676824005088833 0.6155028683968303 0.7961443270356372 0.85360225390136 0.7136532665211658 0.8591287734341465 1.0 15.457708019228148 -8.1207426778315 0.2243332092263022 1.0744336868248876 0.5472412177831708 0.6920010591954786 0.07147585721126529 1.3913564413856134 0.3210655305114054 0.2944006108855315 0.2556122364674586 7.572814560700062e-09 8.1207426778315 -0.5271924690417168 TPAT(ph)TPEAR ddPTM_PC-9_AZD4547_30min_R2 3 TPATTPEAR 9 0 A0A0C4DG98;Q8NI27;Q8NI27-2;H0Y7U4;H7C477 A0A0C4DG98 THOC2 THO complex subunit 2 1 T(0.017)PAT(0.492)T(0.492)PEAR;T(0.061)PAT(0.469)T(0.469)PEAR;T(0.234)PAT(0.552)T(0.214)PEAR 126.39 0.0034134 35528500.0 173906.0 165791.0 194561.0 315100.0 262022.0 226641.0 191867.0 269488.0 188081.0 253476.0 True False 229204.49053048747 219379.69853029054 191980.99401610086 242458.5632464708 225644.76812894264 212469.1024419154 208942.7913043702 227844.8218181775 198022.5776850282 244601.88239208926 0.9370512127256639 0.8968847516006915 0.784871286102211 0.9912375198234051 0.9224980851424563 0.8686323276177164 0.8542157945025189 0.9314925117908508 0.8095709474860219 1.0 17.9000759809484 -11.00188044253778 2.9591006385482586 1.0031762001999132 0.8893881053890093 0.24461790215209955 0.05876458570094235 103395966.93415968 126134412.76783271 2719445.717556115 0.014195019113686628 9.956794814554713e-12 11.00188044253778 -0.1137880948109039 TPAT(ph)TPEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPATTPEAR 9 0 A0A0C4DG98;Q8NI27;Q8NI27-2;H0Y7U4;H7C477 A0A0C4DG98 THOC2 THO complex subunit 2 1 T(0.04)PAT(0.48)T(0.48)PEAR;T(0.115)PAT(0.442)T(0.442)PEAR 120.27 0.0041249 18715200.0 69845.0 78921.0 100809.0 86126.0 102904.0 106896.0 118642.0 113193.0 99372.0 92550.0 True False 81668.37899836879 86755.75530928122 103212.6688802615 81300.63944425955 82740.69990254506 101290.18558034695 107403.3708663037 110221.8036878969 100825.12750664595 109328.58237460312 0.7469993411104564 0.7935322440386318 0.9440593359805391 0.7436357234166934 0.7568075804645722 0.9264748831489149 0.9823905929585468 1.0081700621547733 0.9222211183638972 1.0 16.738311096484097 -6.912011248985759 4.56460024632929 0.9761691237585889 0.8025880205313353 0.68981079613099 0.05794275456522355 0.13379641679886917 5.00783789199796 0.021947719059363536 0.019190955570706963 1.224584479976976e-07 6.912011248985759 -0.17358110322725362 TPAT(ph)TPEAR ddPTM_PC-9_Lapatinib_30min_R1 2 TPATTPEAR 9 0 A0A0C4DG98;Q8NI27;Q8NI27-2;H0Y7U4;H7C477 A0A0C4DG98 THOC2 THO complex subunit 2 1 T(0.041)PAT(0.48)T(0.48)PEAR;T(0.283)PAT(0.358)T(0.358)PEAR 118.03 0.004455399999999999 10856900.0 64075.0 58643.0 74579.0 62659.0 73852.0 82258.0 70923.0 69450.0 89159.0 62741.0 True False 63161.278750084064 58507.21573651521 68447.40250326537 67267.1518842966 69508.17055861843 78740.01709276356 74595.04591109579 72676.90053969008 79116.97453410739 73585.69825287248 0.8583363377627324 0.7950894959977 0.9301726303941605 0.9141334998702791 0.9445880410043553 1.0700451169489293 1.013716628124595 0.9876498051284452 1.0751678167437786 1.0 16.167137778106248 -5.956797731853435 0.9137345258148695 1.0292841244025281 0.8217800188127816 0.7796208810019007 0.03965998922151759 0.2924091599981025 0.4869134975361146 0.017411563196664093 0.04170798572323571 1.1045929528212402e-06 5.956797731853435 -0.20750410558974652 TPCNAGTFSQPEK ddPTM_PC-9_Lapatinib_30min_R1 1 TPCNAGTFSQPEK 13 0 J3QT28;O43684-2;O43684;J3QSX4 J3QT28 BUB3 Mitotic checkpoint protein BUB3 0 97.463 0.013845 2352000.0 6074.2 5958.6 5595.1 5883.6 5055.4 5464.6 5695.2 4288.7 5267.3 4727.6 False True 5987.580794128147 5944.803227795293 5135.09247571058 6316.299571114235 4758.051311298812 5230.891796604778 5990.069589172383 4487.968658669091 4674.041206872032 5544.759360868971 1.0798630570668764 1.0721481025397697 0.9261163815242311 1.139147645557038 0.8581168273735748 0.9433938348200915 1.0803119124422422 0.8094072919272262 0.842965564900461 1.0 12.436909134334135 -5.95551577369566 0.5591777459461114 0.905422623588804 1.0948933653345632 0.24592574854665872 0.09552045066674753 1.96196446760069 1.0874832783453197 0.06806070084373346 0.20915848750634225 1.1078583269228147e-06 5.95551577369566 0.18947074174575917 TPDFHDK ddPTM_PC-9_AZD4547_30min_R2 1 TPDFHDK 7 0 A0A3B3IRN8;A0A3B3ITX0;P24311 A0A3B3IRN8 COX7B Cytochrome c oxidase subunit 7B, mitochondrial 0 89.296 0.014012 1695300.0 22213.0 25021.0 31727.0 23119.0 21214.0 21276.0 34183.0 34721.0 28776.0 23002.0 False True 29276.27194089757 33108.54893767699 31306.27924994647 17789.271734989383 18268.80228029475 19945.60835662658 37225.2207787545 29355.667259206115 30297.04061263166 22196.706981263913 1.3189466331924582 1.4915973331370138 1.4104019698224555 0.801437427182563 0.823041106760355 0.898584117610893 1.677060512182102 1.3225235294579971 1.3649340254932942 1.0 14.438058039269444 -1.5233882682606463 0.011089455236932385 0.001240959850280169 2.6040051496689762 0.022752578463611672 0.28717100667607875 86720.49634221484 74.60423071685409 7424.726095906762 10303.218005452383 0.02996482403803629 1.5233882682606463 2.602764189818696 TPDSEDKLFS(ph)PVIAR ddPTM_PC-9_AZD4547_30min_R2 1 TPDSEDKLFSPVIAR 15 1 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5;X6R5W5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 TPDS(0.001)EDKLFS(0.999)PVIAR 64.53399999999999 0.016868 8843600.0 17201.0 17800.0 16092.0 18257.0 17762.0 20851.0 23296.0 23762.0 19501.0 21056.0 True False 22670.56019697379 23553.501902028293 15878.609565673987 14048.130717838201 15296.052894437411 19547.183673811836 25369.29886966809 20090.128896438917 20531.783047919464 20318.8358489476 1.1157410968575738 1.1591954419597434 0.781472407362177 0.6913846256878843 0.7528016372665198 0.9620228156341086 1.2485606487628609 0.988744091728044 1.010480285413738 1.0 14.310530125997007 -7.007243429348821 24.838056353700804 1.0673344806103204 0.8924331220816413 0.19426287977188372 0.15493354111101681 551.9824585114337 1892776.3656885813 0.0629371430339234 0.05331252609933227 9.834597055639824e-08 7.007243429348821 -0.17490135852867916 TPDT(ph)PNNDPR ddPTM_PC-9_AZD4547_30min_R2 1 TPDTPNNDPR 10 0 Q16513-3;Q16513-2;Q16513;B1AL79 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 T(0.344)PDT(0.656)PNNDPR 97.163 0.01284 5884400.0 15267.0 12801.0 17082.0 25885.0 19766.0 16661.0 16564.0 25201.0 16637.0 22493.0 True False 20121.588426672795 16938.672912801358 16855.481518819484 19917.6131692634 17021.832085995375 15619.185036179519 18038.163911280157 21306.764511369314 17516.39785489133 21705.52691633636 0.9270260290953161 0.7803852437257676 0.7765525151169421 0.9176286411306924 0.7842164878837441 0.7195948339049055 0.8310401300465085 0.9816285314563398 0.8070017338168307 1.0 14.405774824962561 -8.738783246588973 0.7104110164133323 0.9962590091519054 0.8190446863949532 0.2855222804502022 0.07749400331705963 1.2794908138324077 1.3432483556420074 0.07989236612155032 0.029722676474781405 1.8248062234116172e-09 8.738783246588973 -0.17721432275695215 TPDT(ph)PNNDPR ddPTM_PC-9_Lapatinib_30min_R1 1 TPDTPNNDPR 10 0 Q16513-3;Q16513-2;Q16513;B1AL79 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 T(0.005)PDT(0.995)PNNDPR 81.709 0.038909 4074200.0 10409.0 12898.0 13573.0 11278.0 14236.0 18225.0 16281.0 14580.0 18087.0 16167.0 True False 10260.565751223183 12868.135473450757 12457.080333295147 12107.421742305112 13398.666469052867 17445.55923455002 17123.950516455192 15257.440026906846 16049.851595446324 18961.4444088266 0.5411278555576106 0.6786474276959938 0.6569689557772479 0.6385284518023889 0.706626888762533 0.9200543407141003 0.9030931477184275 0.8046560007741008 0.8464466761812237 1.0 14.210781246848896 -6.625456809380394 3.8601770920455625 0.882939419158634 0.6374689576562926 0.8204373780000257 0.05916995671473908 0.10008202697021008 2.8190982345275306 0.020362989719731564 0.02034842254893699 2.3688807054382714e-07 6.625456809380394 -0.24547046150234142 TPDVFS(ph)SSPLHLQPPPLGK ddPTM_PC-9_Lapatinib_30min_R1 1 TPDVFSSSPLHLQPPPLGK 19 0 G5E9C8;Q07889 G5E9C8 SOS1 Son of sevenless homolog 1 1 T(0.157)PDVFS(0.31)S(0.267)S(0.267)PLHLQPPPLGK 74.69800000000001 0.0024192 3007700.0 29225.0 30156.0 32759.0 30538.0 43910.0 56835.0 48543.0 49556.0 64971.0 47329.0 True False 28808.24614079138 30086.175634779105 30065.68147339688 32783.86639178166 41327.30013038152 54404.299538855994 51056.319017276815 51858.55267307238 57653.281805039165 55509.75458807163 0.5189762836202833 0.5419979940110249 0.5416287947318295 0.590596493086037 0.7445051853870428 0.9800853911637869 0.9197720183804992 0.9342241387645435 1.038615325051863 1.0 15.760453694422415 -6.490753809726776 1.792598404629556 0.9742699987911234 0.5351200896015165 0.9700474645892999 0.03535670829769355 0.054813803421460285 0.35435676283821155 0.01338853288354474 0.01493947400256192 3.2303247900912106e-07 6.490753809726776 -0.43914990918960695 TPDVFSS(ph)SPLHLQPPPLGK ddPTM_PC-9_AZD4547_30min_R2 1 TPDVFSSSPLHLQPPPLGK 19 0 G5E9C8;Q07889 G5E9C8 SOS1 Son of sevenless homolog 1 1 T(0.005)PDVFS(0.099)S(0.448)S(0.448)PLHLQPPPLGK 85.855 0.00071971 6677200.0 45990.0 52999.0 99613.0 108340.0 94953.0 79642.0 79908.0 121920.0 85533.0 85156.0 True False 60613.86334857417 70129.89029806732 98292.06653402209 83363.88683631433 81770.41495808573 74661.97314995561 87019.65719769236 103080.06544288507 90054.09976091975 82174.714359469 0.7376218319837655 0.8534242053010099 1.196135177349672 1.0144712699778105 0.9950800023518831 0.9085759984920752 1.0589590469037642 1.2544012625582939 1.0958857656259418 1.0 16.3264069160343 -5.067637985745438 5.007974331410609 1.063794780647936 0.7606513014364013 0.5727690125661601 0.09549825744530306 0.14414222505618052 6.9053756824531085 0.026654724496464693 0.07958406969267252 8.557797668180924e-06 5.067637985745438 -0.3031434792115347 TPEAPAHSEKPR ddPTM_PC-9_AZD4547_30min_R2 2 TPEAPAHSEKPR 12 1 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;Q9NUQ6-2 B8ZZZ7 SPATS2L SPATS2-like protein 0 ; 55.261 0.036696 2942500.0 42205.0 38522.0 38890.0 42034.0 41205.0 40948.0 44809.0 41126.0 39666.0 39570.0 False True 55625.31208146494 50973.48316123228 38374.29318972539 32343.710718826267 35484.397000072844 38387.51508681822 48796.91419346485 34770.921681464 41762.66378025603 38184.666344170626 1.456744746178903 1.3349202190688785 1.0049660469426547 0.8470340012219053 0.9292839350811818 1.0053123088943412 1.2779190933251225 0.9105990705290588 1.0937024669493185 1.0 15.220705797121829 -5.176624472316326 3.5432565409439145 1.0052991671962974 1.4312157255925555 0.6649944508662327 0.11121458807614823 0.14709642353035848 3.4696274019478595 0.03078559149871153 0.09668237033218847 6.658486563296867e-06 5.176624472316326 0.4259165583962581 TPEAPAHSEKPR ddPTM_PC-9_Lapatinib_30min_R1 2 TPEAPAHSEKPR 12 1 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;Q9NUQ6-2 B8ZZZ7 SPATS2L SPATS2-like protein 0 ; 74.611 0.0093029 3120900.0 32245.0 34525.0 29823.0 28298.0 32438.0 33025.0 31939.0 31942.0 28378.0 28910.0 False True 31785.180386991193 34445.05948370967 27371.06806010914 30379.12931936072 30530.060615561757 31612.597735035077 33592.64514127277 33426.14193000401 25181.770806412125 33907.05497984641 0.937420852559551 1.0158670372340812 0.8072381419258584 0.8959530498127126 0.9004043740663451 0.9323309781349306 0.9907273032482319 0.9858167260433485 0.7426705392544295 1.0 15.049297863102405 -6.7850919592665635 19.46385234061494 0.9331989956089219 0.9105394297372664 0.012069107802546553 0.08345388354503815 123.94241226695497 101984.53346749496 0.029636905107698258 0.02618481970031527 1.6402424248747304e-07 6.7850919592665635 -0.022659565871655518 TPEAS(ph)PEPK ddPTM_PC-9_Lapatinib_30min_R1 1 TPEASPEPK 9 0 A0A087WW66;Q99460-2;Q99460 A0A087WW66 PSMD1 26S proteasome non-ATPase regulatory subunit 1 1 T(0.462)PEAS(0.538)PEPK 86.014 0.01199 3297700.0 16425.0 17318.0 17763.0 19041.0 20636.0 20742.0 21262.0 25654.0 24332.0 21437.0 True False 16190.776488023906 17277.901235014753 16302.594707162883 20441.338658913963 19422.231051936993 19854.913011963607 22362.842324235015 26845.978494531428 21591.473932680936 25142.35688699299 0.6439641502503671 0.6872029266259126 0.6484115542722559 0.813023963934303 0.7724904685441317 0.7896997525413076 0.8894489257609769 1.067759025742721 0.8587688906703472 1.0 14.617832276316552 -6.785430199428368 0.5844827842687506 0.9980923436875438 0.641893939879218 0.7759532166805745 0.06373629213424821 0.3940287328992799 0.2922247052515565 0.05290562987221331 0.05983445279817729 1.6389654575232155e-07 6.785430199428368 -0.3561984038083259 TPEDGDYS(ph)YEIIEK ddPTM_PC-9_AZD4547_30min_R2 3 TPEDGDYSYEIIEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.023)PEDGDY(0.001)S(0.975)Y(0.001)EIIEK;T(0.087)PEDGDYS(0.913)YEIIEK;TPEDGDYS(1)YEIIEK 126.63 0.00064966 0.0 14177.099999999999 16954.4 22311.699999999997 24170.8 27874.9 20840.9 17497.4 26572.8 20365.5 21221.0 True False 18685.122898001104 22434.57823863756 22015.832279794184 18598.595495137397 24004.951290797966 19537.71522840847 19054.634703044743 22466.584342197297 21441.97875300772 20478.0592491697 0.9124459828271426 1.0955422076702503 1.0750936898811265 0.908220611574385 1.172227846336135 0.9540804131231647 0.9304902613668007 1.097105153805443 1.0470708426081492 1.0 14.321791373975683 -4.739570855246683 24.599142298822688 1.0305222144087303 0.9124454235541687 0.16797239744999537 0.07920914167518371 2687.7005033327646 3023109.237797534 0.019297925929832083 0.9193568072125936 1.821499870716665e-05 4.739570855246683 -0.11807679085456158 TPEDGDYSYEIIEK ddPTM_PC-9_Lapatinib_30min_R1 4 TPEDGDYSYEIIEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 0 ;;; 176.29 0.00042637 14806300.0 45724.4 39457.5 47228.4 41798.2 45508.6 45063.7 39563.7 42469.0 42543.2 39554.0 False True 45072.36167117198 39366.13858301157 43345.463258896096 44872.17906270768 42831.87362135003 43136.43059961547 41612.114799329145 44442.26478070692 37751.53681624326 46390.85619760791 0.9715785688278822 0.8485753833756886 0.934353594903712 0.9672634381130792 0.9232826710268522 0.9298476927407896 0.8969895839403548 0.9579962178624015 0.8137710728044263 1.0 15.501552852610319 -10.726197267340778 5.026790536321959 1.0000081768729607 0.9173318603749111 0.2128937904707099 0.04841214054255103 4.176222859574273e-06 6.617980860139359e-07 0.04412538953798685 0.010700920620321202 1.8784633782673747e-11 10.726197267340778 -0.08267631649804963 TPEEIRR ddPTM_PC-9_Lapatinib_30min_R1 2 TPEEIRR 7 1 P09525-2;P09525;Q6P452;B4E1S2 P09525-2 ANXA4 Annexin A4;Annexin 0 ; 89.55 0.018538 0.0 12315.0 10659.2 13647.0 12969.9 12473.0 12956.5 12366.2 12894.1 12859.8 11116.5 False True 12139.385841705587 10634.519277299296 12524.996338943414 13923.749712318055 11739.362662861515 12402.38069807667 13006.4613277187 13493.206958226308 11411.393904302578 13037.972213194842 0.9310792846620844 0.8156574583382549 0.9606552410249594 1.0679382870770946 0.9003978894034539 0.9512507386328884 0.9975831452191429 1.0349160695840995 0.8752429992720713 1.0 13.670431885203197 -5.399795832423072 6.905671882486351 0.9765381156811825 0.8743383796038169 0.30927247337958785 0.06012351770283938 0.2688793967685413 13.931363762455762 0.01530312698676936 0.032112095896328074 3.982943699960145e-06 5.399795832423072 -0.10219973607736565 TPEQYYQTFS(ph)PSSSHSPAR ddPTM_PC-9_Lapatinib_30min_R1 1 TPEQYYQTFSPSSSHSPAR 19 0 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4;A8MXE8;Q7Z5J4-4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 TPEQYYQT(0.024)FS(0.972)PS(0.001)S(0.001)S(0.001)HSPAR 88.329 0.0024042 0.0 13980.0 9701.2 20391.0 11305.0 17002.0 21814.0 11734.0 13175.0 19900.0 10365.0 True False 13780.642636381992 9678.737467439958 18714.53069153625 12136.407412374472 16001.97578721809 20881.06607091764 12341.52910509705 13787.158597702168 17658.65244370995 12156.576439505638 1.1335956883056788 0.796172961656099 1.5394573286866362 0.998340895791547 1.3163225573292106 1.7176765329307464 1.0152142066075747 1.134131691295715 1.452600782102108 1.0 13.56944937073477 -5.250359110607419 24.980449484826515 1.275104214200522 0.9648843418363207 0.20176717354260143 0.24404513379752837 1121.7766919827418 2529032.3566082804 0.06070594991815935 0.15734820144673417 5.6187652705266875e-06 5.250359110607419 -0.31021987236420134 TPESFLGPNAALVDLDSLVSRPGPT(ph)PPGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPESFLGPNAALVDLDSLVSRPGPTPPGAK 30 1 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 TPESFLGPNAALVDLDS(0.036)LVS(0.066)RPGPT(0.898)PPGAK 75.044 1.7833000000000001e-06 1306900.0 3083.6 2277.8 1991.1 943.93 2237.7 3815.0 3432.6 1125.6 1111.3 884.79 True False 3605.5925761238495 2503.9249305442304 2038.5753752888 891.0446623623502 1799.2387484638573 3614.934684076328 3107.4392781281026 1096.054192671782 1127.5506601269535 1045.1954230062138 3.4496827069461955 2.395652406649837 1.9504250883776406 0.8525148912339361 1.721437645879512 3.458620851667121 2.973070116582044 1.0486595793916578 1.0787941042488187 1.0 10.029556996770301 -4.830945539992105 2.24330258393798 1.8357426807156554 3.754265937205687 0.28169980207210077 0.8253049134322655 0.850790053207291 5.549189905401938 0.24120251746711363 3.164560783079256 1.4758915967109013e-05 4.830945539992105 1.9185232564900316 TPESQPDT(ph)PPGTPLVSQDEKR ddPTM_PC-9_AZD4547_30min_R2 3 TPESQPDTPPGTPLVSQDEKR 21 1 A0A0D9SEV0;M0R000;M0QYI1;A0A0D9SFD6;M0R3C8;A0A0D9SFL2;M0QYH2;Q96T60-2;Q96T60 A0A0D9SEV0 PNKP Bifunctional polynucleotide phosphatase/kinase;Polynucleotide 3-phosphatase;Polynucleotide 5-hydroxyl-kinase 1 T(0.002)PES(0.023)QPDT(0.755)PPGT(0.218)PLVS(0.002)QDEKR;TPES(0.002)QPDT(0.998)PPGT(0.001)PLVSQDEKR;T(0.008)PES(0.241)QPDT(0.736)PPGT(0.015)PLVSQDEKR 132.39 2.7035e-05 75330000.0 91886.0 100153.0 115448.0 155684.0 124456.0 107500.0 111569.0 144768.0 118514.0 122632.0 True False 121103.83665246988 132525.49865133947 113917.0840876167 119793.4590938227 107177.43266693542 100778.00800607975 121498.42486220833 122397.43203769362 124778.4080888738 118338.69100627552 1.0233663700576823 1.1198830874706196 0.9626359994262204 1.012293258233438 0.9056837772631081 0.8516065806468611 1.0267007673404571 1.0342976671188873 1.0544176805391297 1.0 16.85256231647277 -5.274435525618001 24.724024192002624 0.9776246127021434 1.071624730549375 0.25017550242245257 0.06257673759536579 844.2538505143925 1606118.3045721597 0.01784912482224509 0.03752567427370895 5.315749100646285e-06 5.274435525618001 0.0940001178472315 TPESQPDT(ph)PPGTPLVSQDEKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPESQPDTPPGTPLVSQDEKR 21 1 A0A0D9SEV0;M0R000;M0QYI1;A0A0D9SFD6;M0R3C8;A0A0D9SFL2;M0QYH2;Q96T60-2;Q96T60 A0A0D9SEV0 PNKP Bifunctional polynucleotide phosphatase/kinase;Polynucleotide 3-phosphatase;Polynucleotide 5-hydroxyl-kinase 1 T(0.005)PES(0.086)QPDT(0.894)PPGT(0.015)PLVSQDEKR 116.92 2.5414e-06 18419000.0 42784.0 38549.0 50014.0 37757.0 48410.0 37100.0 49896.0 35557.0 43406.0 36411.0 True False 50026.48617748181 42375.88995853436 51206.523439151264 35641.5976998456 38924.40801409272 35154.410689182645 45169.489664242814 34623.66642575566 44040.73063391576 43012.026070682565 1.163081369272683 0.9852102732593245 1.190516423360353 0.8286426136093895 0.9049656937835809 0.8173158509532349 1.050159543519639 0.8049764121517519 1.0239166730147216 1.0 15.392452470220096 -5.762884184417821 24.99999671721199 0.911139492539065 1.1001634504198032 0.4597565018332226 0.09601844151919614 32.41101313672415 560838.38683377 0.024853457973383963 0.03923334616035099 1.7262981915847994e-06 5.762884184417821 0.18902395788073822 TPESQPDT(ph)PPGTPLVSQDEKR ddPTM_PC-9_Lapatinib_30min_R1 3 TPESQPDTPPGTPLVSQDEKR 21 1 A0A0D9SEV0;M0R000;M0QYI1;A0A0D9SFD6;M0R3C8;A0A0D9SFL2;M0QYH2;Q96T60-2;Q96T60 A0A0D9SEV0 PNKP Bifunctional polynucleotide phosphatase/kinase;Polynucleotide 3-phosphatase;Polynucleotide 5-hydroxyl-kinase 1 TPES(0.004)QPDT(0.989)PPGT(0.007)PLVSQDEKR;T(0.006)PES(0.227)QPDT(0.742)PPGT(0.025)PLVSQDEKR;T(0.013)PES(0.255)QPDT(0.699)PPGT(0.033)PLVSQDEKR 122.44 1.1896e-06 148510000.0 150542.0 160186.0 179426.0 147116.0 166340.0 166769.0 151121.0 155989.0 169365.0 137958.0 True False 148395.24347397807 159815.0991587985 164674.2868843889 157935.401404589 156556.20823702245 159636.6786275266 158945.30593926826 163236.81840584127 150289.33020748413 161803.85648252 0.9171304485564564 0.9877088385471433 1.0177401853346986 0.9760917003956027 0.9675678419564464 0.9866061421395877 0.9823332360217226 1.008856166685224 0.9288365152391791 1.0 17.3038864682486 -4.759823511645678 24.991056466556916 0.9845755395423713 0.917130364838836 0.42595577690638475 0.023268867515635717 39.14971449850884 605298.6359213707 0.005556397629362434 0.03444082377483976 1.738507178814244e-05 4.759823511645678 -0.06744517470353528 TPESQPDTPPGT(ph)PLVSQDEKR ddPTM_PC-9_AZD4547_30min_R2 1 TPESQPDTPPGTPLVSQDEKR 21 1 A0A0D9SEV0;M0R000;M0QYI1;A0A0D9SFD6;M0R3C8;A0A0D9SFL2;M0QYH2;Q96T60-2;Q96T60 A0A0D9SEV0 PNKP Bifunctional polynucleotide phosphatase/kinase;Polynucleotide 3-phosphatase;Polynucleotide 5-hydroxyl-kinase 1 TPES(0.006)QPDT(0.265)PPGT(0.73)PLVSQDEKR 105.79 6.8414e-05 43367000.0 57438.0 73834.0 71026.0 80842.0 61801.0 79077.0 57418.0 62848.0 60550.0 60174.0 True False 75702.08921538168 97699.39659743593 70084.14883243598 62205.12589644927 53220.99791291109 74132.30268927256 62528.090766595255 53136.285703366426 63750.549384724996 58067.32657554011 1.3036951015284028 1.6825192816538272 1.206946366667374 1.0712586503448938 0.9165394904770688 1.2766611976329483 1.076820553900516 0.9150806285913841 1.097872988896631 1.0 15.82543899332148 -5.478308374655469 4.355510853471419 1.0556106414898607 1.4917883182420315 0.6468611528704873 0.12920416535435464 0.12087822067958129 4.966485730622701 0.03395961850617874 0.07101466712520593 3.3242342926349844e-06 5.478308374655469 0.4361776767521708 TPESQPDTPPGT(ph)PLVSQDEKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPESQPDTPPGTPLVSQDEKR 21 1 A0A0D9SEV0;M0R000;M0QYI1;A0A0D9SFD6;M0R3C8;A0A0D9SFL2;M0QYH2;Q96T60-2;Q96T60 A0A0D9SEV0 PNKP Bifunctional polynucleotide phosphatase/kinase;Polynucleotide 3-phosphatase;Polynucleotide 5-hydroxyl-kinase 1 TPES(0.005)QPDT(0.365)PPGT(0.63)PLVSQDEKR 103.41 9.413299999999999e-05 16711000.0 46194.0 41230.0 41248.0 63835.0 58591.0 54155.0 49885.0 39120.0 40280.0 39455.0 True False 54013.73182691179 45323.04192042262 42231.508753911134 60258.5319058623 47110.51414901273 51315.01646557103 45159.531663875925 38093.14145106622 40869.01879772673 46607.87917439183 1.158897010198847 0.9724330461559567 0.9061023479719875 1.2928829411094653 1.0107843348275987 1.1009944536108711 0.9689248355391447 0.8173111955713288 0.8768693088309787 1.0 15.508286246122934 -7.491972584619511 4.42647967024562 0.8851225106086936 1.0674956775377729 0.34915269704477114 0.10803144135998259 0.2267755300927998 10.447447460373077 0.04968809596334448 0.03070118392418081 3.221272131683723e-08 7.491972584619511 0.18237316692907923 TPETLLPFAEAEAFLKK ddPTM_PC-9_AZD4547_30min_R2 1 TPETLLPFAEAEAFLKK 17 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 0 140.77 5.8467e-05 926760.0 2191.1 2264.9 2723.5 3883.2 3143.0 2220.9 2680.9 3087.0 3155.0 2453.3 False True 2887.824222288779 2996.9846324665104 2687.384610496714 2987.98823484194 2706.6487021290845 2082.026771913514 2919.4949064085345 2609.9750822029705 3321.766858939842 2367.4107137264027 1.2198239222053802 1.2659335429588947 1.13515774635769 1.2621334428865207 1.1432949451634047 0.8794531341105226 1.233201695625145 1.102459774753136 1.4031223393896208 1.0 11.209094300517023 -6.407124101712329 6.993555873859418 1.1235927782896082 1.2171494577150834 0.10775794507143333 0.13291964591907612 0.6415246567814397 34.903557633615556 0.041424802910791425 0.04693314640198419 3.916299509969903e-07 6.407124101712329 0.09355667942547519 TPETLLPFAEAEAFLKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPETLLPFAEAEAFLKK 17 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 0 96.24700000000001 0.011656 0.0 735.14 701.28 2101.1 2227.5 2698.7 859.01 1082.5 1257.8 2282.8 625.54 False True 859.5846823231569 770.8984438019398 2151.1981924661227 2102.700396652437 2169.909107780046 813.9620033993206 979.957763378685 1224.7840827492605 2316.1816313666955 738.9454502280846 1.1632586438658437 1.0432413428677212 2.9111732020301755 2.8455421114013393 2.9364943070023326 1.1015183910369584 1.3261571108885086 1.6574756396040002 3.134441968147686 1.0 9.529324056730502 -6.773632348462579 24.999090637726685 1.6651509724556428 2.1943937683043644 0.09376127193528072 0.8313105734736229 667.1199779718994 1367779.4612416187 0.3161979621301388 0.2808819869214193 1.6840991301394435e-07 6.773632348462579 0.5292427958487216 TPETLLPFAEAEAFLKK ddPTM_PC-9_Lapatinib_30min_R1 1 TPETLLPFAEAEAFLKK 17 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 0 112.67 0.00015502 1139400.0 4973.4 5390.1 6413.8 3677.9 6523.6 3857.1 4263.4 3524.1 5065.9 4531.4 False True 4902.478403990139 5377.619554616757 5886.48212198397 3948.385035114731 6139.894673891074 3692.140824339254 4484.137991023585 3687.8425513595616 4495.324995708055 5314.646452289036 0.9224467606643195 1.0118489730018823 1.10759618251721 0.7429252482851703 1.1552781034468627 0.6947105244882351 0.8437321336948485 0.6939017645795038 0.8458370723365624 1.0 12.375758006805215 -6.775207616021423 24.996292846266446 0.7982611659177345 0.9823698208426304 0.294443312864615 0.13191504415297745 274.06877106566685 497570.0179453048 0.043583992256783735 0.03863482770111416 1.6780016516942197e-07 6.775207616021423 0.1841086549248958 TPETVVPTAPELQISTSTDQPVT(ph)PKPTSR ddPTM_PC-9_AZD4547_30min_R2 1 TPETVVPTAPELQISTSTDQPVTPKPTSR 29 1 Q14676;Q14676-2 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 TPETVVPTAPELQISTSTDQPVT(0.908)PKPT(0.026)S(0.066)R 98.667 7.2645e-11 5683700.0 19013.0 17010.0 26702.0 32403.0 29974.0 27701.0 19279.0 23188.0 26659.0 30391.0 True False 25058.73850503243 22508.149851320308 26347.914033223144 24932.98897135955 25812.627488901413 25968.852090943445 20994.79365162823 19604.82740723112 28068.14031457284 29327.020340300456 0.8544590692903548 0.7674884659315414 0.8984176956094139 0.8501712305595963 0.8801653625012271 0.8854923476578934 0.7158856715756327 0.6684902584627958 0.9570743972241293 1.0 14.83994287858011 TPFNTDLGENS(ph)GIGK ddPTM_PC-9_AZD4547_30min_R2 2 TPFNTDLGENSGIGK 15 0 Q6P0N0 Q6P0N0 MIS18BP1 Mis18-binding protein 1 1 TPFNTDLGENS(1)GIGK;TPFNTDLGENS(1)GIGK 169.67 1.7538e-05 8630800.0 27474.0 25957.0 28807.0 31473.0 26374.0 28860.0 27744.0 29491.0 28421.0 24620.0 True False 36210.160505299595 34347.092633199354 28425.00035784058 24217.386103002762 22712.42534837812 27055.379637725255 30213.162252750306 24933.843585762166 29923.276037378528 23758.06129374477 1.524121015498572 1.4457026694447732 1.196436022552251 1.0193334297600676 0.9559881619784375 1.1387873489849372 1.271701502879155 1.049489824842188 1.259499908995394 1.0 14.536129493633585 -5.2838984508427345 2.8196255359877966 1.1041119521591058 1.5098036187026753 0.7039704819777413 0.0989534144879045 0.15125240129021558 2.362800459682367 0.02794449567511091 0.08242136891335052 5.201175991131231e-06 5.2838984508427345 0.4056916665435695 TPFNTDLGENS(ph)GIGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPFNTDLGENSGIGK 15 0 Q6P0N0 Q6P0N0 MIS18BP1 Mis18-binding protein 1 1 TPFNTDLGENS(1)GIGK 161.08 1.4102e-14 0.0 12191.0 13053.0 11568.0 9028.9 12985.0 11018.0 10801.0 9026.8 8328.5 7155.9 True False 14254.695516774509 14348.815575728258 11843.824991884298 8523.040005088753 10440.682463602438 10440.196683919527 9777.851087531802 8789.856064685186 8450.288556525988 8453.20802392677 1.6863060126317313 1.6974402540566842 1.4011041675965383 1.008261003510658 1.2351148148785798 1.2350573479758917 1.156703000784511 1.0398248853932772 0.999654632017511 1.0 13.045283238114836 -5.492902427305452 2.974430572157211 1.1123595558906376 1.6912130184261267 0.8787782587542429 0.08877747418626704 0.08714834365233899 1.5377219619761622 0.02651471161500784 0.05908549292718636 3.214382631041017e-06 5.492902427305452 0.5788534625354891 TPFNTDLGENS(ph)GIGK ddPTM_PC-9_Lapatinib_30min_R1 3 TPFNTDLGENSGIGK 15 0 Q6P0N0 Q6P0N0 MIS18BP1 Mis18-binding protein 1 1 TPFNT(0.005)DLGENS(0.995)GIGK;TPFNT(0.001)DLGENS(0.999)GIGK;TPFNTDLGENS(1)GIGK 160.76 5.4642999999999995e-06 7098200.0 33650.4 37068.6 45829.4 39862.7 46143.0 41715.9 35446.3 36226.5 45069.0 28789.9 True False 33170.53912527241 36982.769934188 42061.48363859991 42794.33593606897 43428.95946062846 39931.80820151252 37281.53597392208 37909.715441340246 39992.85462239017 33766.1958548696 0.9823593770480578 1.0952601854571817 1.2456684140370524 1.2673721410609355 1.2861667819285998 1.1825971860479434 1.10410826656819 1.1227120639908594 1.184405101311482 1.0 15.043292032082341 -7.254856598158615 21.136311830419093 1.113032353439888 1.1851245664617949 0.12191682142132554 0.09374389924101244 156.23967377262161 501665.7052771454 0.03967171031151603 0.029848761759297546 5.5608784435264135e-08 7.254856598158615 0.07209221302190683 TPGDFSYAY(ph)QKPEETTRSPDEEDYDYESYEK ddPTM_PC-9_AZD4547_30min_R2 1 TPGDFSYAYQKPEETTRSPDEEDYDYESYEK 31 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.015)PGDFS(0.123)Y(0.099)AY(0.333)QKPEET(0.284)T(0.071)RS(0.071)PDEEDY(0.003)DYESYEK 48.607 0.026786 11730000.0 13896.0 11699.0 15316.0 16757.0 17225.0 19248.0 16734.0 16633.0 15248.0 13940.0 True False 18314.638945244325 15480.472963585906 15112.899832703382 12893.932543069212 14833.606075142692 18044.41951721884 18223.293581946506 14062.752038316165 16053.978150591029 13451.964843005766 1.361484300545646 1.1507964185347128 1.1234715529725166 0.9585166697616893 1.1027092508984142 1.3413965712674965 1.3546938157083834 1.0454050543871272 1.1934299812668747 1.0 13.71552929301755 -9.215424010486869 1.263832510602478 1.0000343585467604 1.178088512817636 0.14861975620640344 0.12932687791134165 10.290946836055614 16.724153902384675 0.13635713694686757 0.03995695400207537 6.089420844498219e-10 9.215424010486869 0.17805415427087556 TPGDFSYAYQKPEET(ph)TRSPDEEDYDYESYEK ddPTM_PC-9_AZD4547_30min_R2 1 TPGDFSYAYQKPEETTRSPDEEDYDYESYEK 31 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.003)PGDFS(0.027)Y(0.075)AY(0.275)QKPEET(0.405)T(0.107)RS(0.107)PDEEDYDYESYEK 60.382 0.00038981 52264000.0 90183.0 72701.0 94126.0 144470.0 123920.0 119740.0 87870.0 117690.0 110060.0 110370.0 True False 118859.31807707058 96200.17650445843 92877.82773916418 111164.67353924985 106715.84701490193 112252.6388711442 95690.25977325423 99503.71474715513 115877.54690805686 106505.97989401342 1.1159872731592184 0.9032373262063733 0.8720433146719937 1.0437411462705888 1.0019704726541867 1.0539562096217452 0.8984496445033212 0.9342547230322052 1.0879909937767749 1.0 16.700574908843258 TPGDFSYAYQKPEET(ph)TRSPDEEDYDYESYEK ddPTM_PC-9_Lapatinib_30min_R1 4 TPGDFSYAYQKPEETTRSPDEEDYDYESYEK 31 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.002)PGDFS(0.006)Y(0.023)AY(0.109)QKPEET(0.625)T(0.118)RS(0.118)PDEEDY(0.001)DY(0.001)ESYEK;T(0.005)PGDFS(0.018)Y(0.069)AY(0.266)QKPEET(0.418)T(0.112)RS(0.112)PDEEDYDYESYEK;T(0.002)PGDFS(0.006)Y(0.025)AY(0.025)QKPEET(0.615)T(0.163)RS(0.163)PDEEDY(0.001)DYESYEK;T(0.002)PGDFS(0.007)Y(0.033)AY(0.028)QKPEET(0.669)T(0.112)RS(0.112)PDEEDY(0.03)DY(0.005)ES(0.001)YEK 68.38600000000001 3.6455e-05 188223000.0 251935.0 228082.0 275741.0 228147.0 274060.0 251201.0 257275.0 232086.0 269062.0 229263.0 True False 248342.36070077922 227553.89014231673 253070.63937104138 244925.69145608085 257940.32962269126 240457.7188081315 270595.4406437567 242869.5628315985 238757.4042115322 268890.80407625466 0.9235807135685901 0.8462687704179902 0.941165095773499 0.9108741829141261 0.9592753850724551 0.894257874062291 1.00633951232865 0.90322747803128 0.8879344350646632 1.0 18.036660891081432 -5.288704307030809 24.678490328450003 0.9351141586546629 0.8849247308380134 0.1939776298381779 0.042885511337816096 877.5269782225482 794280.7817012307 0.01067033551027011 0.022223174860626534 5.143937616036862e-06 5.288704307030809 -0.05018942781664948 TPGHPPPPEIPS(ph)ELGACDFEKPESPR ddPTM_PC-9_Lapatinib_30min_R1 2 TPGHPPPPEIPSELGACDFEKPESPR 26 1 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 TPGHPPPPEIPS(0.833)ELGACDFEKPES(0.167)PR;TPGHPPPPEIPS(0.99)ELGACDFEKPES(0.01)PR 62.589 0.00054386 16230900.0 83733.0 81400.0 85147.0 77913.0 93109.0 94014.0 94844.0 87576.0 98848.0 72151.0 True False 82538.95206524832 81211.52330120104 78146.54233692492 83642.98193014886 87632.51167933704 89993.24037733799 99754.55824474378 91645.1006719061 87714.69732441421 84622.20421483558 0.9753817314389687 0.9596952012148533 0.9234756180367212 0.988428305622946 1.0355734938888972 1.0634707664771603 1.1788224990156337 1.0829911785237956 1.0365447005106074 1.0 16.368748644638607 -6.365864624931637 1.9484429100551115 1.0838358425919472 0.9541744765810353 0.5725702840738923 0.04517369059050588 0.23082398278006871 1.7283570418022216 0.016440691274330076 0.019909895573326 4.306608319852046e-07 6.365864624931637 -0.12966136601091194 TPGHPPPPEIPSELGACDFEKPES(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 TPGHPPPPEIPSELGACDFEKPESPR 26 1 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 TPGHPPPPEIPS(0.217)ELGACDFEKPES(0.783)PR;TPGHPPPPEIPS(0.014)ELGACDFEKPES(0.986)PR 72.92699999999999 5.906600000000001e-05 16457100.0 126053.0 110166.0 116320.0 142279.0 133526.0 121389.0 114205.0 128233.0 106473.0 110563.0 True False 166135.23193472112 145775.0050864522 114777.52079786225 109478.77473863716 114988.21972653137 113798.52664046554 124369.02375559969 108417.53635119346 112100.94541106245 106692.22302275793 1.5571447217786785 1.366313316532525 1.0757815100860697 1.0261176647831665 1.0777563393913339 1.0666056383152858 1.1656803113856875 1.0161709380454798 1.0506946264223103 1.0 16.703095493941177 -5.07896161438912 2.3688411680642782 1.061127973629067 1.5624182286860067 0.9336976682731489 0.044236989994439105 0.08037368811537443 0.7892766811933173 0.012350633835979804 0.06322221438575672 8.337548737341975e-06 5.07896161438912 0.5012902550569396 TPGRQS(ph)PGPGHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPGRQSPGPGHR 12 1 O15169-2;O15169 O15169-2 AXIN1 Axin-1 1 T(0.002)PGRQS(0.998)PGPGHR 59.84 0.026317 370550.0 1165.3 718.48 2647.8 2319.7 2926.2 2520.9 2685.2 2751.1 2000.1 1158.0 True False 1362.5622742758865 789.8059461310996 2710.933593837418 2189.7347295688696 2352.8321159024595 2388.699566209178 2430.838416835514 2678.886540031397 2029.3476786825522 1367.9362332770431 0.9960714842765128 0.57737044090062 1.981768980081093 1.6007578981390944 1.7199866913869142 1.7462068100110069 1.7770114992949422 1.9583416791394048 1.4835104366093326 1.0 10.417785264828034 -5.258686043216523 24.999981404299362 1.7001805977117168 0.7867209059394438 0.6036728222073977 0.28090782891854654 133.33788851665653 1210676.4206955277 0.06621265979848567 0.15984794238153688 5.512060259755174e-06 5.258686043216523 -0.913459691772273 TPGT(ph)PGTPSYPR ddPTM_PC-9_AZD4547_30min_R2 4 TPGTPGTPSYPR 12 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 T(0.004)PGT(0.906)PGT(0.086)PS(0.004)YPR;TPGT(0.98)PGT(0.018)PS(0.002)YPR;TPGT(0.626)PGT(0.373)PS(0.001)YPR;TPGT(0.994)PGT(0.004)PS(0.001)YPR 174.21 0.00018454 197796000.0 147362.0 141116.0 212603.0 326223.0 261323.0 248222.0 234636.0 277315.0 212044.0 269776.0 True False 194220.05067998657 186728.9873262148 209783.74530766738 251017.32744510766 225042.8122133248 232700.63910032727 255518.14944983902 234462.33881474438 223252.21294359418 260331.2243534231 0.7460497724096106 0.7172746480564827 0.8058339748860361 0.964222897459004 0.8644480229840155 0.893863729478778 0.9815117263957169 0.9006308766728673 0.8575698650750752 1.0 17.989988834654554 -5.566001188927777 4.091446057730738 0.9174398549917643 0.7358166748741816 0.7443998396073817 0.04595209719552768 0.10102730010842302 3.6272285448899995 0.012510904334699743 0.023661383599094706 2.7164318323050803e-06 5.566001188927777 -0.18162318011758272 TPGT(ph)PGTPSYPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TPGTPGTPSYPR 12 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 T(0.028)PGT(0.924)PGT(0.044)PS(0.004)YPR;T(0.167)PGT(0.734)PGT(0.086)PS(0.013)YPR;TPGT(0.754)PGT(0.025)PS(0.221)YPR;T(0.14)PGT(0.613)PGT(0.242)PS(0.005)YPR 136.01 0.0001519 196487000.0 457299.0 439544.0 473588.0 520809.0 622427.0 462217.0 519918.0 449452.0 387371.0 349572.0 True False 534710.6886330467 483179.0234749037 484880.1340124911 491629.76021556003 500466.8974796057 437977.5268334754 470667.6031596476 437654.3612337577 393035.56804106734 412946.63638957 1.2948663132555598 1.1700761815119305 1.174195625497382 1.190540658022847 1.2119408499249038 1.0606153150023274 1.139778270806943 1.0598327305925277 0.951782950643243 1.0 18.65559583382894 -7.37914334585493 0.6336426346281668 0.9735730178578423 1.220044475336641 0.762048026288629 0.0486335918244141 0.3764082053804958 0.302266801672388 0.0436701270372551 0.02868877597985748 4.1769247779429584e-08 7.37914334585493 0.24647145747879873 TPGT(ph)PGTPSYPR ddPTM_PC-9_Lapatinib_30min_R1 4 TPGTPGTPSYPR 12 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 T(0.001)PGT(0.957)PGT(0.04)PS(0.003)YPR;TPGT(0.964)PGT(0.033)PS(0.002)YPR;TPGT(0.962)PGT(0.037)PS(0.001)YPR;T(0.002)PGT(0.973)PGT(0.015)PS(0.01)YPR 148.78 0.00016207 212573000.0 295294.0 233407.0 269953.0 259224.0 259033.0 224812.0 233082.0 215181.0 225292.0 199589.0 True False 291083.0534097128 232866.56043198294 247758.50638871492 278288.19770591427 243797.18821847235 215197.31482236818 245149.84548101525 225179.09481686103 199917.2425300656 234087.69271437434 1.2434786726053224 0.9947834409052791 1.0584003948085439 1.1888202855904597 1.041478026424675 0.9193021312954904 1.047256447523444 0.9619433307483479 0.8540271391969233 1.0 17.836689560417334 -6.542649343936495 5.7298638572650695 0.9610024089389456 1.1090093557620628 0.4897218301276719 0.07890650432601343 0.16099279219177964 17.0986225225868 0.025896063209624568 0.02658982087751278 2.8664914852365617e-07 6.542649343936495 0.1480069468231172 TPGVLLPGAGGAAGFGMTSPPPPT(ph)SPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPGVLLPGAGGAAGFGMTSPPPPTSPSR 28 0 Q96L91-5;Q96L91-2;Q96L91;Q96L91-4;Q96L91-3;A0A0A0MR80;A0A0A0MR72;Q6ZTU2-4;Q6ZTU2-5;Q6ZTU2-2;Q6ZTU2-6;Q6ZTU2 Q96L91-5 EP400;EP400NL E1A-binding protein p400;EP400 N-terminal-like protein 1 TPGVLLPGAGGAAGFGMTSPPPPT(0.378)S(0.378)PS(0.243)R 72.082 9.326899999999999e-05 5677700.0 30228.0 25325.0 32020.0 41693.0 41544.0 37420.0 38066.0 36227.0 36131.0 29345.0 True False 35345.0033697859 27839.09863290571 32783.47823652621 39357.076380529776 33403.751426099305 35457.629325854825 34460.11290602586 35276.079635679314 36659.34752186356 34665.01620510781 1.0196159482705767 0.8030891567505941 0.9457222821576422 1.1353543338234644 0.96361562990348 1.0228649286086364 0.9940890464937456 1.0176276689719668 1.0575315270287364 1.0 15.081192814503474 -5.533287266308071 24.99202377777874 1.0250970627344844 0.9021158296074683 0.35749850554334006 0.06500255425984211 184.2726523195561 442457.7641580154 0.016499237701836904 0.02861573846596745 2.9289552319360067e-06 5.533287266308071 -0.12298123312701614 TPGVLLPGAGGAAGFGMTSPPPPT(ph)SPSR ddPTM_PC-9_Lapatinib_30min_R1 2 TPGVLLPGAGGAAGFGMTSPPPPTSPSR 28 0 Q96L91-5;Q96L91-2;Q96L91;Q96L91-4;Q96L91-3;A0A0A0MR80;A0A0A0MR72;Q6ZTU2-4;Q6ZTU2-5;Q6ZTU2-2;Q6ZTU2-6;Q6ZTU2 Q96L91-5 EP400;EP400NL E1A-binding protein p400;EP400 N-terminal-like protein 1 TPGVLLPGAGGAAGFGMTSPPPPT(0.365)S(0.365)PS(0.269)R;TPGVLLPGAGGAAGFGMTSPPPPT(0.333)S(0.333)PS(0.333)R 71.765 0.00021649 7752900.0 33807.0 26978.0 37517.0 27703.0 32174.0 29485.0 28143.0 29110.0 34083.0 25090.0 True False 33324.90598055549 26915.534098523378 34432.49707980802 29740.371034498898 30281.588576517763 28223.995282892054 29600.106835243434 30462.556871279718 30244.213630098813 29426.773069676452 1.1324689221495363 0.9146614219232607 1.1701078129864615 1.0106568927581665 1.029048904030941 0.9591264124021865 1.005890342279684 1.0351986879142592 1.0277788039649074 1.0 14.844841725034527 -5.933718641057142 24.999984404157203 1.0095874808776972 1.0622616811510301 0.15815318017123614 0.06508701783871358 117.58187438578605 44347.51403506407 0.01741869206405133 0.025836092298855074 1.1648804561958695e-06 5.933718641057142 0.052674200273332916 TPGVVASAPTKPQS(ph)PAQNATSSQDSSQDTLTEQITLENQVHQR ddPTM_PC-9_Lapatinib_30min_R1 1 TPGVVASAPTKPQSPAQNATSSQDSSQDTLTEQITLENQVHQR 43 1 Q96L91-5;Q96L91-2;Q96L91;Q96L91-4;Q96L91-3;A0A0A0MR80;A0A0A0MR72 Q96L91-5 EP400 E1A-binding protein p400 1 TPGVVAS(0.001)APT(0.004)KPQS(0.534)PAQNAT(0.144)S(0.144)S(0.144)QDS(0.012)S(0.012)QDT(0.006)LTEQITLENQVHQR 93.805 5.2768e-19 9751000.0 14661.0 14144.0 17023.0 8287.3 12492.0 14605.0 15082.0 15292.0 13520.0 11050.0 True False 14451.93145150188 14111.250437004772 15623.434650680278 8896.775687622368 11757.245120216941 13980.378195917865 15862.87216320723 16002.522146190637 11997.235228088375 12959.977776800522 1.115120079709711 1.0888329193175876 1.2055140000816646 0.6864807826714305 0.9071963951406942 1.0787347352511627 1.2239891484693082 1.23476462859655 0.9257141821311191 1.0 13.66177562390415 -6.9883048742802805 23.847154635803975 1.120778033974316 0.9988095288831261 0.07139317787270072 0.15702994083486385 306.84315188852185 625668.4506494161 0.058696057400004574 0.051715372872942304 1.027294884986218e-07 6.9883048742802805 -0.12196850509118995 TPHDILEDINAS(ph)PEMR ddPTM_PC-9_AZD4547_30min_R2 3 TPHDILEDINASPEMR 16 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 TPHDILEDINAS(1)PEMR;TPHDILEDINAS(1)PEMR;TPHDILEDINAS(1)PEMR 86.539 0.0030929 24653000.0 26380.0 20332.9 31008.0 35979.0 37536.0 34609.0 25364.9 34514.0 29347.6 32894.0 True False 34768.29126191319 26905.112293469163 30596.813659732707 27684.597420008784 32324.77431852285 32444.89375890624 27622.326961677732 29180.65435281934 30898.854221687143 31742.39107215436 1.0953267881704496 0.8476082419976029 0.963910172683034 0.8721648396643557 1.0183471763373042 1.022131372685662 0.8702030952516709 0.9192960381115626 0.9734255416187849 1.0 14.954123186298851 -4.736795463776841 24.994888913700215 0.9414785109926234 1.0953274863067393 0.3633411258245465 0.06045700930739156 2660.01614305707 2697759.924347526 0.014932035152442362 1.0275637142464344 1.8331775761836447e-05 4.736795463776841 0.1538489753141159 TPHDILEDINAS(ph)PEMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TPHDILEDINASPEMR 16 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 TPHDILEDINAS(1)PEMR;TPHDILEDINAS(1)PEMR;TPHDILEDINAS(1)PEMR;TPHDILEDINAS(1)PEMR;TPHDILEDINAS(1)PEMR 162.39 4.3181000000000006e-05 31032500.0 40314.2 40600.6 53161.8 56057.1 62655.6 57197.100000000006 54445.0 50869.2 49817.5 40940.4 True False 47138.59781825536 44631.15924798232 54429.37892924925 52916.4024265703 50378.684956987985 54197.58338626007 49287.57545233486 49533.93740037259 50545.98669204944 48362.570435971946 0.9746917377078411 0.922845060666705 1.125444293770722 1.094160255535368 1.0416874972285688 1.1206514231499172 1.0191264651159835 1.0242205274418041 1.0451468198731941 1.0 15.561603304382137 -5.249018352656999 24.909937743442978 1.061112786999145 0.9487683876894777 0.5232758865337047 0.04196485277859258 560.8414241798408 1124742.6654592233 0.010804248148137111 0.028187330660038774 5.6361383781666175e-06 5.249018352656999 -0.11234439930966733 TPHDILEDINAS(ph)PEMR ddPTM_PC-9_Lapatinib_30min_R1 2 TPHDILEDINASPEMR 16 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 TPHDILEDINAS(1)PEMR;TPHDILEDINAS(1)PEMR 141.93 1.7354e-05 15575400.0 27345.0 24791.0 25262.2 22832.5 25890.0 24004.0 21202.0 23719.0 28005.0 21614.0 True False 26955.055285541173 24733.597962654494 23185.239430912006 24511.678216987184 24367.201101698418 22977.404876056997 22299.73581781725 24821.071330466628 24850.781994276236 25349.951101155333 1.063317841442017 0.9756862198257752 0.9146068699854546 0.9669319723409666 0.9612326668585911 0.9064082524013151 0.8796756936071933 0.9791368524310644 0.9803088729880687 1.0 14.629695343890935 -4.808939893695156 3.2371624592182986 0.9448496626212891 1.0763676533076636 0.4753246216813447 0.035969333928922265 0.2672030843170408 4.444444772682647 0.009454460658921006 0.08620238929946535 1.5526018750046536e-05 4.808939893695156 0.1315179906863745 TPHPVLT(ph)PVAANQAK ddPTM_PC-9_AZD4547_30min_R2 2 TPHPVLTPVAANQAK 15 0 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;A0A494C104;H0Y837 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 TPHPVLT(1)PVAANQAK;T(0.003)PHPVLT(0.997)PVAANQAK 126.25 5.0616000000000005e-05 22100200.0 65963.0 61679.0 78877.0 115179.0 93452.0 89015.0 70658.0 101090.0 72527.0 70442.0 True False 86937.86188436608 81615.53055141594 77831.03944268377 88626.2610478111 80477.8028989396 83448.87797824369 76946.42511731666 85468.86331710356 76360.62915319484 67975.84702087614 1.2789522410462424 1.200654852102849 1.1449807961757503 1.3037904628182564 1.1839176181831756 1.2276254233745054 1.1319671396471978 1.2573416450530601 1.1233494321849882 1.0 16.052734602779317 -9.77733497032369 0.4019289987771986 0.954515436810423 1.2262911774358463 0.5992335187218495 0.05396780137442807 4.232114893401946 0.7673258367924982 0.3285645104848181 0.03527834454146807 1.6698022029451928e-10 9.77733497032369 0.2717757406254233 TPHPVLT(ph)PVAANQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPHPVLTPVAANQAK 15 0 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;A0A494C104;H0Y837 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 TPHPVLT(1)PVAANQAK;T(0.112)PHPVLT(0.888)PVAANQAK 128.99 3.4402e-05 14890000.0 171775.0 182001.0 161614.0 185639.0 185173.0 171338.0 196689.0 169154.0 148571.0 134109.0 True False 200853.11478910214 200068.85647729403 165467.49068450776 175238.24867975808 148889.67992550274 162352.73365668958 178057.19401495636 164713.8867334779 150743.56980628258 158421.90009374038 1.2678367995223807 1.2628863582554595 1.0444735897410549 1.1061491408452193 0.9398301613438718 1.0248124379307613 1.1239430527572105 1.0397166467263332 0.9515323936721222 1.0 17.273412260439507 -5.2688926054075145 4.361930287356078 1.031666082384509 1.2704383858613433 0.7485577439363731 0.05485586194604105 0.09492714909597294 4.701685185917195 0.014911412156908435 0.03735662202956511 5.384029051194503e-06 5.2688926054075145 0.2387723034768343 TPHS(ph)PPLAK ddPTM_PC-9_AZD4547_30min_R2 2 TPHSPPLAK 9 0 Q8IZW8 Q8IZW8 TNS4 Tensin-4 1 T(0.006)PHS(0.994)PPLAK;T(0.029)PHS(0.971)PPLAK 72.652 0.01797 35765000.0 98324.0 77763.0 121737.0 148112.0 128314.0 114790.0 105919.0 122365.0 120065.0 115523.0 True False 129588.98673375126 102898.36901165315 120122.68783845723 113967.066707589 110499.81596086259 107612.16315365497 115345.58580770859 103456.30091796798 126411.39078244436 111478.5749324648 1.1624564344517139 0.9230326910259693 1.0775405759468055 1.0223226012409268 0.9912202055668978 0.9653169967309668 1.0346883773638698 0.9280375263196823 1.133952338904817 1.0 16.766406939660648 -4.739872237536254 24.756711626612997 1.007733139113477 1.1624571004772564 0.36328521027611216 0.061156337022598484 1582.5942117973793 1816538.5460547549 0.014041176984927631 0.6574102243474288 1.8202362641363112e-05 4.739872237536254 0.15472396136377942 TPHS(ph)PPLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPHSPPLAK 9 0 Q8IZW8 Q8IZW8 TNS4 Tensin-4 1 T(0.009)PHS(0.991)PPLAK;T(0.062)PHS(0.938)PPLAK 69.65 0.022550999999999998 22241000.0 47427.0 51199.0 55847.0 65759.0 69983.0 67981.0 71791.0 73073.0 66428.0 49034.0 True False 55455.45437405173 56281.69835759686 57178.60428092695 62074.73642355455 56270.33352716896 64415.95668628904 64990.4367581701 71154.91117724335 67399.38383057072 57923.47604706955 0.9573916856955846 0.9716560917694486 0.9871404166846391 1.0716680120010689 0.9714598875496142 1.1120872068165177 1.1220051211249447 1.2284295769718954 1.163593562233746 1.0 15.821860562174162 -6.870381141850903 3.8521479229535927 1.1444713546344667 0.99470784071353 0.5353580809374415 0.061292778576309846 0.16853695940721203 4.693217008728394 0.02231214931722836 0.01966133464070341 1.347779536528222e-07 6.870381141850903 -0.14976351392093668 TPHS(ph)PPLAK ddPTM_PC-9_Lapatinib_30min_R1 4 TPHSPPLAK 9 0 Q8IZW8 Q8IZW8 TNS4 Tensin-4 1 T(0.001)PHS(0.999)PPLAK;T(0.064)PHS(0.936)PPLAK;T(0.022)PHS(0.978)PPLAK;T(0.003)PHS(0.997)PPLAK 87.667 0.0060715000000000005 52732000.0 403559.0 304161.0 362918.0 343867.0 366445.0 344378.0 309803.0 314694.0 381697.0 343294.0 True False 397804.17465634237 303456.7338920957 333080.2829439919 369156.12628668436 344891.4255585897 329649.75572432776 325843.0834622789 329315.8320869295 338706.2644123998 402631.91048949806 0.9880095548629357 0.7536827707549792 0.8272575378813143 0.9168575978935309 0.8565923777360055 0.8187372812143912 0.8092828088715982 0.8179079290724006 0.8412305522446522 1.0 18.619101991655263 -10.235496715647354 8.009457004455424 0.9999999999870688 0.8437939451031405 0.35789614523810787 0.060982971049014616 0.0 0.0 0.0569745096546269 0.013818348310223527 5.8143782941624415e-11 10.235496715647354 -0.15620605488392825 TPHT(ph)PGTPK ddPTM_PC-9_AZD4547_30min_R2 1 TPHTPGTPK 9 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 T(0.003)PHT(0.66)PGT(0.337)PK 84.68700000000001 0.031823000000000004 2795200.0 19731.0 24259.0 31555.0 41527.0 34246.0 35178.0 36445.0 44272.0 42093.0 33797.0 True False 26005.047569704668 32100.247339399113 31136.56008232926 31953.591735754337 29491.534028989066 32978.31409895701 39688.53439667984 37430.77966935209 44317.95004543734 32613.777317006177 0.7973638661028251 0.9842542011428008 0.9547057300257387 0.979757463392393 0.9042661247831283 1.0111773861214397 1.216925411948054 1.147698388491606 1.358872037871189 1.0 14.993193922779952 -7.121963227928955 3.3473720397770297 1.193816371636763 0.9330619802405702 0.6103514491434356 0.09632342439494532 0.16411462168722338 3.416823185658355 0.03732845881272818 0.028291979618861672 7.5515616465227e-08 7.121963227928955 -0.2607543913961927 TPHT(ph)PGTPK ddPTM_PC-9_Lapatinib_30min_R1 3 TPHTPGTPK 9 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 T(0.021)PHT(0.691)PGT(0.288)PK;TPHT(0.997)PGT(0.003)PK;T(0.001)PHT(0.657)PGT(0.342)PK 104.82 0.0065461 8004000.0 254562.0 226117.0 159722.0 129254.0 163756.0 129930.0 118441.0 99998.0 193098.0 109044.0 True False 250931.8991990467 225593.43997908678 146590.2737047497 138759.7703387038 154124.19403668304 124373.19678162319 124573.295443736 104644.27214064678 171349.26982791504 127892.11010800352 1.9620592621948092 1.7639355530890493 1.1462026358072894 1.0849752202971916 1.2051110416938684 0.972485297776316 0.9740498873506364 0.8182230479446763 1.3397954704415496 1.0 16.96456773897568 -5.21368339648286 2.4030542095861334 1.0465864330205128 1.9639464672486888 0.8528675363748528 0.13375295810412 0.10854726560457703 1.1672618773919177 0.03650716974955183 0.13699941285573822 6.113875680188401e-06 5.21368339648286 0.917360034228176 TPHTATLR ddPTM_PC-9_Lapatinib_30min_R1 2 TPHTATLR 8 0 P41250 P41250 GARS Glycine--tRNA ligase 0 ; 112.41 0.0031309000000000003 2575900.0 3090.78 1854.58 3663.7 3781.2 1670.01 2776.12 3774.6 3494.5 1940.56 2161.85 False True 3046.704910420365 1850.285833955055 3362.4847282909773 4059.2820617134325 1571.7832951659861 2657.391819051798 3970.0303187403547 3656.867227299448 1721.993697797276 2535.5228920159466 1.2016081258875906 0.7297452686313266 1.3261504121611494 1.6009644694968515 0.6199049908464013 1.0480646131887044 1.5657639421207743 1.442253682194895 0.6791473676769493 1.0 11.308067584524649 TPHTPGT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 TPHTPGTPK 9 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 T(0.009)PHT(0.054)PGT(0.937)PK 92.611 0.016859 4725000.0 20606.0 21429.0 20078.0 26151.0 22901.0 24480.0 23423.0 21318.0 20512.0 21165.0 True False 27158.279368574036 28355.505183065416 19811.752601267865 20122.290978922425 19721.591450034393 22949.26173012872 25507.601623636503 18023.79293890603 21596.22244392205 20424.019792124614 1.3297225347894597 1.3883410548788802 0.9700221994941056 0.9852267665095715 0.9656077329908839 1.123640789800734 1.2489021203099346 0.8824801935344727 1.0573933370476576 1.0 14.317979220467548 -5.25791560526499 24.995317840921953 1.0323456050479296 1.359031827842784 0.6550503803049968 0.0957294213215275 183.67422565565207 1302849.5337449808 0.02580209094665157 0.06280255404842644 5.521847327382837e-06 5.25791560526499 0.3266862227948544 TPHTPGT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPHTPGTPK 9 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 T(0.005)PHT(0.012)PGT(0.983)PK 99.34299999999999 0.0102 4673100.0 44662.0 46180.0 32678.0 52169.0 47752.0 40187.0 40155.0 38555.0 34227.0 30085.0 True False 52222.39448529104 50764.44520701227 33457.16745200511 49246.140064180014 38395.3383906002 38079.52297482973 36351.22770297559 37542.97210239923 34727.50512387767 35539.17234727102 1.4694319264106637 1.4284082001394827 0.9414166184028823 1.385686182642954 1.0803667011550002 1.071480297929723 1.022849585459379 1.0563828480738966 0.9771613357941444 1.0 15.117122463156013 -1.5228787464270361 0.35710629749886724 1.001639025120087 7.131239507008218 0.6022648219101523 0.12073113658440923 42.44270269593729 0.5939827748239597 0.09714361550053766 176.35585582872469 0.029999999920788868 1.5228787464270361 6.129600481888131 TPHVQAVQGPLGS(ph)PPK ddPTM_PC-9_AZD4547_30min_R2 5 TPHVQAVQGPLGSPPK 16 0 Q15149 Q15149 PLEC Plectin 1 TPHVQAVQGPLGS(1)PPK;TPHVQAVQGPLGS(1)PPK;TPHVQAVQGPLGS(1)PPK;TPHVQAVQGPLGS(1)PPK;TPHVQAVQGPLGS(1)PPK 163.85 6.240299999999999e-06 206575400.0 279609.0 252067.0 228650.0 250714.0 259346.0 289528.0 296775.0 269001.0 245981.0 271169.0 True False 368518.8457715043 333542.72831115534 225617.9516027442 192915.7607926869 223340.28453781988 271423.76839055173 323187.4000706458 227433.07647803123 258983.05347983545 261675.45584741968 1.4083049729600314 1.2746427716386237 0.8622052491399872 0.7372329214749668 0.8535010813855135 1.0372534463026453 1.2350695980409148 0.8691417991095243 0.989710909802889 1.0 17.99741908591559 -5.13015552216162 4.211130899013391 0.9466160782674418 1.3797440243192034 0.6069158049620575 0.12824147384689233 0.16085111129330415 4.620446747453613 0.03691149341582842 0.1121345985264528 7.410448233977516e-06 5.13015552216162 0.43312794605176164 TPHVQAVQGPLGS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TPHVQAVQGPLGSPPK 16 0 Q15149 Q15149 PLEC Plectin 1 TPHVQAVQGPLGS(1)PPK;TPHVQAVQGPLGS(1)PPK;TPHVQAVQGPLGS(1)PPK;TPHVQAVQGPLGS(1)PPK;TPHVQAVQGPLGS(1)PPK 153.36 2.2094000000000002e-05 245919000.0 298244.0 348302.0 259744.0 319143.0 324163.0 256679.0 352003.0 286270.0 263136.0 266415.0 True False 348730.8186124923 382879.1207122731 265937.28204460593 301262.45238556596 260645.58717356584 243218.3013824451 318658.7275589721 278755.7158281372 266983.8661955964 314713.93056002044 1.108088281926193 1.2165941305202332 0.8450127440224254 0.9572580783109342 0.8281984426611106 0.772823436667224 1.0125345484133226 0.8857431742284267 0.8483382534751787 1.0 18.26368151422679 -5.262682234480164 24.999624605424568 0.8895101284593987 1.1623412204684878 0.6619302866731429 0.07673579141877906 57.56869641616939 1158004.3985940006 0.019506405396188597 0.04456367181948993 5.461573284996951e-06 5.262682234480164 0.27283109200908906 TPHVQAVQGPLGS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 3 TPHVQAVQGPLGSPPK 16 0 Q15149 Q15149 PLEC Plectin 1 TPHVQAVQGPLGS(1)PPK;TPHVQAVQGPLGS(1)PPK;TPHVQAVQGPLGS(1)PPK 145.44 5.5283e-06 281282000.0 449290.0 438750.0 372860.0 439080.0 436520.0 416900.0 403500.0 392270.0 408890.0 348269.0 True False 442883.0422103041 437734.1013317206 342204.89008122263 471371.40792794287 410844.75183134 399070.15884136606 424391.2556593367 410496.2962520392 362836.5023974153 408466.8326107269 1.084257048190682 1.0716515182736654 0.8377788911134125 1.1540016723393665 1.0058215723548827 0.9769952588088935 1.0389858411436454 1.0049684906564897 0.8882887750722278 1.0 18.63985941114145 -8.064967799645968 8.743754779597708 0.9444826499705508 1.0213909297942476 0.12971275924173287 0.0815727058863594 0.8438581586383194 106.70373312153869 0.05337678409347331 0.020161315752862695 8.61057592119521e-09 8.064967799645968 0.07690827982369686 TPHVQAVQGPLGS(ph)PPKR ddPTM_PC-9_AZD4547_30min_R2 1 TPHVQAVQGPLGSPPKR 17 1 Q15149 Q15149 PLEC Plectin 1 TPHVQAVQGPLGS(1)PPKR 76.156 0.0038994 95879000.0 31166.0 20346.0 28847.0 30685.0 32529.0 28682.0 26966.0 23825.0 27380.0 29103.0 True False 41076.13970692898 26922.446612284723 28464.469931705044 23611.04732852414 28012.90984141169 26888.51000586403 29365.921759936035 20143.3936940349 28827.250902622152 28084.112828263766 1.462611262036737 0.958636178999753 1.0135434971995443 0.8407261241580704 0.9974646524429136 0.9574277873860241 1.0456417811561511 0.7172522706062714 1.026461155419177 1.0 14.777466608726245 -4.760612660698613 6.201263179007117 0.9440276716866244 1.4800542767265357 0.723053969556452 0.09498620601664759 0.06458090727799458 10.339370878085774 0.022591612501724916 0.14662815992791225 1.735351035598205e-05 4.760612660698613 0.5360266050399113 TPHVQAVQGPLGS(ph)PPKR ddPTM_PC-9_Lapatinib_30min_R1 3 TPHVQAVQGPLGSPPKR 17 1 Q15149 Q15149 PLEC Plectin 1 TPHVQAVQGPLGS(1)PPKR;TPHVQAVQGPLGS(1)PPKR;TPHVQAVQGPLGS(1)PPKR 71.042 0.0063746 210122600.0 159258.0 168582.0 150252.0 150473.0 157147.0 142272.0 132442.0 144028.0 169023.0 141434.0 True False 156986.9517156593 168191.6587366475 137898.8605494925 161539.28638321292 147903.92242288933 136187.35821223067 139299.19871631684 150720.06668006416 149985.849848904 165880.67845104105 0.9463847940674616 1.0139315820696293 0.8313135793581453 0.9738282233448335 0.891628390985527 0.8209959079256224 0.8397554194802161 0.9086053185184465 0.9041791440054404 1.0 17.339786327419986 -5.25108016990934 24.985119099524717 0.8909189711332209 0.9801581899725192 0.2526892501730259 0.05709885554008361 893.7979226122503 2155718.5283820615 0.014323720271612276 0.03702291474593616 5.609444172354548e-06 5.25108016990934 0.0892392188392983 TPHYGSQT(ph)PLHDGSR ddPTM_PC-9_AZD4547_30min_R2 2 TPHYGSQTPLHDGSR 15 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 TPHYGS(0.001)QT(0.999)PLHDGSR;TPHYGSQT(1)PLHDGSR 161.95 1.5757000000000002e-05 14391800.0 8848.1 14437.6 24140.0 48967.0 38812.0 33351.0 19905.0 39197.0 31906.0 32269.0 True False 11661.611748086962 19104.271857344032 23819.887827204202 37678.41468260848 33423.62374388608 31265.55669777463 21676.506438905544 33140.00430745376 33592.48602261 31139.272131919195 0.3744985335136742 0.6135105463098243 0.7649468403208987 1.2099966409936205 1.073359184578541 1.0040554758415816 0.6961147436932581 1.0642510899759832 1.0787819920869681 1.0 14.926447601938678 -5.26884072337475 2.0449150004745382 1.0069660430115934 0.4160097248327128 0.7145184276083493 0.13330932328804887 0.2070871800654436 1.5719284467479877 0.039793668005358614 0.15334953807678817 5.384672280774833e-06 5.26884072337475 -0.5909563181788806 down TPHYGSQT(ph)PLHDGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPHYGSQTPLHDGSR 15 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 TPHYGS(0.002)QT(0.997)PLHDGS(0.002)R 82.755 0.015668 4756000.0 9742.7 7267.8 18276.0 19548.0 19711.0 16154.0 16962.0 16679.0 16036.0 11405.0 True False 11391.946682903705 7989.299152783106 18711.76915211597 18452.788935471086 15848.771046597427 15306.855802508255 15355.236565754498 16241.193922861274 16270.496162868561 13472.636218069676 0.8455618112529957 0.59300192059426 1.3888721441925003 1.3696494610848293 1.1763674747887016 1.1361440741625979 1.1397351132482783 1.2054948756857526 1.2076698204800007 1.0 13.717744553038298 -5.257755675443216 24.999989290380242 1.2106853558381911 0.719281838618629 0.7204085169450583 0.12045989525149618 154.9250196057798 1051409.8277478481 0.03134218615234351 0.07645973408216744 5.5238811332884145e-06 5.257755675443216 -0.4914035172195621 TPHYGSQT(ph)PLHDGSR ddPTM_PC-9_Lapatinib_30min_R1 1 TPHYGSQTPLHDGSR 15 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 TPHYGSQT(0.999)PLHDGSR 88.176 0.01034 6103700.0 12777.0 8860.3 12898.0 8114.4 12123.0 9760.6 10468.0 9232.1 10334.0 11076.0 True False 12594.797636985162 8839.784519725205 11837.5762277198 8711.160044844888 11409.948974735038 9343.161891069896 11009.98181968263 9661.057069438044 9170.076098155718 12990.47184215769 0.9695411983505898 0.6804821739451871 0.9112506744599973 0.6705807264501935 0.8783321432333645 0.7192319112496545 0.8475428724576562 0.7437033224678744 0.7059078538160771 1.0 13.665166213104923 -4.737250691527623 24.853083908233312 0.7888042803276683 0.9695420564142196 0.19619726117392244 0.10512798834181326 3098.828431406007 3183767.933803409 0.023406384762336988 1.4887105750717171 1.8312570450149662e-05 4.737250691527623 0.1807377760865514 TPIKETLPISST(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPIKETLPISSTPSK 15 1 A0A0D9SFF0;Q08050-2;Q08050;Q08050-3 A0A0D9SFF0 FOXM1 Forkhead box protein M1 1 TPIKETLPIS(0.007)S(0.198)T(0.792)PS(0.004)K 112.02 0.00026071 4052200.0 29472.0 20092.0 24343.0 37790.0 37754.0 41453.0 34351.0 41306.0 39510.0 25531.0 True False 34461.02750146654 22086.600976597885 24923.429441341603 35672.74881683305 30356.374719356674 39279.13170616411 31097.024600296718 40221.761267324684 40087.75900442357 30159.568196715216 1.142623371684075 0.7323248407450148 0.8263854866481842 1.1828003830876563 1.006525508633207 1.3023771245651368 1.0310832170231006 1.3336318678364028 1.3291887583718678 1.0 14.880328152820578 -5.76752748699603 24.97695830162108 1.1762683007005608 0.8836325778036836 0.3873935005150465 0.15437079516663604 130.9352693599647 537174.8669967437 0.04258183275286417 0.06501986645009553 1.7079396191807975e-06 5.76752748699603 -0.2926357228968771 TPIKETLPISST(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 1 TPIKETLPISSTPSK 15 1 A0A0D9SFF0;Q08050-2;Q08050;Q08050-3 A0A0D9SFF0 FOXM1 Forkhead box protein M1 1 TPIKETLPIS(0.002)S(0.045)T(0.94)PS(0.013)K 95.822 0.0078564 0.0 50736.0 38413.0 35374.0 36210.0 37500.0 34442.0 22966.0 25887.0 40587.0 23591.0 True False 50012.49533615708 38324.05705858767 32465.68626758878 38873.004193018984 35294.32372783666 32968.99594822343 24155.067106498955 27089.80452513974 36015.664659942515 27668.67291696841 1.8075494797398048 1.3851064405436162 1.1733734525329726 1.4049464645331535 1.2756059473380688 1.191564049608049 0.8730114082083545 0.97907856319796 1.301676620632395 1.0 14.755965828628414 -1.5228787452803376 0.41543694290643907 1.0595679531852418 13.37295358492661 0.6787473773539183 0.14367763989916882 48.986525764439826 0.6329747844972666 0.10569804024375416 499.58945332691724 0.029999999999999995 1.5228787452803376 12.313385631741367 TPIKETLPISSTPS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 TPIKETLPISSTPSK 15 1 A0A0D9SFF0;Q08050-2;Q08050;Q08050-3 A0A0D9SFF0 FOXM1 Forkhead box protein M1 1 TPIKETLPISS(0.165)T(0.165)PS(0.67)K 112.08 0.00091328 0.0 24745.0 23256.0 35902.0 48225.0 50363.0 34932.0 30920.0 36846.0 32538.0 42710.0 True False 32613.39527202583 30773.047204133138 35425.91602204992 37107.47131882277 43370.966778659575 32747.696517845412 33671.82010002307 31152.29733684827 34257.89225235643 41214.73589991224 0.7913042400957198 0.7466515684793862 0.8595448993796744 0.9003447555489925 1.0523169888552393 0.7945628135861753 0.8169849779407362 0.7558533776001851 0.8312049441624442 1.0 15.33087262979127 -5.314542475764885 6.371405178234211 0.8701182276574572 0.7691323344415547 0.19464323674383233 0.08669539263697239 0.3695478125056884 34.76933559288442 0.02427002419959481 0.0519401548912262 4.846827063681752e-06 5.314542475764885 -0.10098589321590246 TPIS(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 2 TPISPLK 7 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 T(0.355)PIS(0.645)PLK;T(0.042)PIS(0.958)PLK 93.667 0.013761 225923000.0 518230.0 435070.0 534040.0 553580.0 543280.0 555940.0 523320.0 573010.0 507670.0 533040.0 True False 683016.3601463712 575697.8692424413 526958.2806644633 425960.68372574216 467854.94969541556 521176.98391534993 569894.4661948266 484464.4709598709 534504.3997711533 514378.4318447493 1.32784797701728 1.1192107475769892 1.0244564080468888 0.828107590355395 0.9095539795817575 1.0132170239841094 1.107928386792923 0.9418444494696327 1.0391267725869162 1.0 18.972470625417266 -4.871158550552303 1.9718493206673209 0.9777073188789537 1.3917607456042982 0.6866620713649769 0.07235220073346318 0.37864374031799375 1.873729649372393 0.021487586522006965 0.270637932690546 1.3453691022329239e-05 4.871158550552303 0.4140534267253445 TPIS(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 2 TPISPLK 7 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 T(0.01)PIS(0.99)PLK;T(0.053)PIS(0.947)PLK 93.556 0.013836000000000001 237490000.0 370870.0 411880.0 436290.0 393880.0 447570.0 356590.0 384330.0 376390.0 377740.0 363760.0 True False 365581.3257907724 410926.3171658312 400419.920328103 422847.24914516223 421244.81255647645 341339.47695189004 404228.7268588669 393878.4534792502 335194.94342145696 426635.43132026703 0.85689396368099 0.9631790681195362 0.9385528977022901 0.9911207979998711 0.9873648122775252 0.8000729707225208 0.9474804415749993 0.9232202123024639 0.7856706658988961 1.0 18.702644258369894 -6.714217151832904 24.999994897656663 0.8900009498255237 0.9502326022493628 0.14139033128666323 0.06895353500883414 229.43601289003456 121465.23621195772 0.02205538651242677 0.02205532129426306 1.9310025538970228e-07 6.714217151832904 0.0602316524238391 TPITSVPLGPLAS(ph)SPTK ddPTM_PC-9_AZD4547_30min_R2 1 TPITSVPLGPLASSPTK 17 0 Q15911 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 TPITSVPLGPLAS(0.615)S(0.385)PTK 212.95 3.4512e-22 17408000.0 81731.0 64813.0 80244.0 100610.0 99743.0 89072.0 81671.0 91640.0 78085.0 76385.0 True False 107719.7578895917 85762.53476270547 79179.91212950186 77415.91890900485 85895.40613950395 83502.31375923294 88939.56078230873 77479.14367770651 82212.413686313 73710.78439978442 1.4613839584904316 1.1635005035023926 1.074197117480864 1.0502658401940879 1.165303107800806 1.1328371342019956 1.2066017409328893 1.0511235812860664 1.1153376586039077 1.0 16.169588090618326 -4.765849618881292 3.4555178600717396 1.1071875983059032 1.5123417982230911 0.7790220044087416 0.05746070112045725 0.1437433698790579 2.7361298259651337 0.014461979276401783 0.15788243070485064 1.7145508942510758e-05 4.765849618881292 0.40515419991718793 TPITSVPLGPLASS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPITSVPLGPLASSPTK 17 0 Q15911 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 TPITSVPLGPLAS(0.053)S(0.931)PT(0.016)K;TPITSVPLGPLAS(0.197)S(0.751)PT(0.052)K 177.66 3.9122e-06 21941000.0 90719.0 90647.0 88458.0 103050.0 105863.0 99281.0 107200.0 104537.0 90081.0 79981.0 True False 106075.93491807602 99645.83509484719 90567.17419883312 97276.44259260783 85119.90509390425 94074.52958578817 97045.23993921027 101793.01451610717 91398.26420849105 94480.9221707522 1.1227233231950102 1.054666199328163 0.9585763148580844 1.029588200005112 0.9009216161128265 0.9956986810074783 1.027141117058782 1.0773922626637797 0.9673726939636559 1.0 16.52773542562108 -4.949716970672566 3.32725038891232 0.9965290582383807 1.1220211607480783 0.445798930252283 0.044956702934562096 0.24976044734812738 5.2655589183023555 0.011998375287753727 0.06496397523599025 1.1227499110492612e-05 4.949716970672566 0.12549210250969767 TPITSVPLGPLASS(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 1 TPITSVPLGPLASSPTK 17 0 Q15911 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 TPITSVPLGPLAS(0.061)S(0.821)PT(0.118)K 109.1 0.00048039 10457000.0 62169.0 51811.0 55312.0 50711.0 63896.0 58049.0 50040.0 52776.0 60029.0 49746.0 True False 61282.4586596017 51691.03481275838 50764.46087049449 54440.45610693692 60137.762904369374 55566.37958882822 52630.82635239957 55228.16562826034 53267.901886606254 58344.52981762156 1.0503548293415643 0.8859619740589005 0.8700808975439255 0.933085865583486 1.0307352393164066 0.9523837069648599 0.9020695944747111 0.9465868659992185 0.9129887935187022 1.0 15.832309779699163 -6.0185081769157645 24.964726604995708 0.9545069916896771 0.9256934809176676 0.026552552061125945 0.057125162173973114 2622.9246813123473 3537930.6447517117 0.01715193145038355 0.02256354577048226 9.582786736231586e-07 6.0185081769157645 -0.028813510772009554 TPITSVPLGPLASSPT(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 TPITSVPLGPLASSPTK 17 0 Q15911 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 TPITSVPLGPLAS(0.01)S(0.286)PT(0.704)K 160.63 7.3033e-05 15621000.0 59167.0 58511.0 69797.0 72219.0 85660.0 74327.0 61525.0 67088.0 69733.0 71001.0 True False 77980.87524994767 77423.53650503259 68871.44617545036 55570.02532242744 73767.58759922913 69679.32094016658 67000.60581028197 56721.09112887366 73418.94401725891 68515.27660102252 1.1381531115176713 1.1300185936033589 1.0051983965050872 0.8110603660848115 1.076658976782533 1.01698955907195 0.9778929478813788 0.8278604997710417 1.0715704242834978 1.0 16.064138075933904 -5.3154290619681674 4.210887264868074 0.9650140647883061 1.1363354390473779 0.3715885458009426 0.08419971499163958 0.20659356577620558 7.677821468450806 0.022176952674787424 0.051754402620154474 4.836942648844596e-06 5.3154290619681674 0.1713213742590718 TPITSVPLGPLASSPT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 TPITSVPLGPLASSPTK 17 0 Q15911 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 TPITSVPLGPLAS(0.015)S(0.3)PT(0.685)K 157.07 6.781e-05 11656000.0 88154.0 70393.0 73259.0 76787.0 88065.0 66185.0 70250.0 73063.0 90745.0 69583.0 True False 86896.9077945364 70230.00933343296 67235.92780791777 82434.17213392293 82885.18984245164 63354.42183477058 73887.20126411012 76457.77370959513 80524.34251278701 81610.32883648046 1.0647783072734391 0.8605529512587822 0.8238654195676122 1.010094841047549 1.0156213193127253 0.7763039646821108 0.9053658074599248 0.9368639337649367 0.9866930284539179 1.0 16.316464134909815 -8.226788133918774 2.935421504091907 0.9982955220026929 0.9177577791192548 0.09686518595794325 0.08486601248064923 0.6354001303467738 10.162184689937028 0.0770752534679951 0.0228070211801444 5.932146476467081e-09 8.226788133918774 -0.08053774288343807 TPKDS(ph)PGIPPSAGAHQLFR ddPTM_PC-9_AZD4547_30min_R2 4 TPKDSPGIPPSAGAHQLFR 19 1 E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2;Q5SVM6 E9PGT3 RPS6KA1 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 T(0.237)PKDS(0.763)PGIPPSAGAHQLFR;T(0.182)PKDS(0.818)PGIPPSAGAHQLFR;T(0.206)PKDS(0.794)PGIPPSAGAHQLFR;T(0.262)PKDS(0.736)PGIPPS(0.001)AGAHQLFR 130.47 1.3676e-05 177781000.0 363659.0 324337.0 692394.0 1133470.0 920341.0 782975.0 532154.0 866108.0 588124.0 741930.0 True False 479294.9974228986 429172.5924942786 683212.4031577974 872166.0034369325 792567.5383920401 734015.4494749804 579514.6750811015 732270.9097818757 619211.033961058 715955.2565259149 0.6694482553960408 0.5994405217119098 0.9542668999638355 1.2181850688114382 1.1070070806350063 1.025225309521017 0.8094286197340396 1.0227886493006986 0.8648739265714783 1.0 19.449509903818537 -5.312000854232862 5.176337820199719 1.0091643814649995 0.6333742569605858 0.6448783611760401 0.10881034672755031 0.11966197089732118 7.372913635578281 0.031063762428935947 0.06886120961294512 4.875275311631626e-06 5.312000854232862 -0.37579012450441374 TPKDS(ph)PGIPPSAGAHQLFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TPKDSPGIPPSAGAHQLFR 19 1 E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2;Q5SVM6 E9PGT3 RPS6KA1 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 T(0.258)PKDS(0.742)PGIPPSAGAHQLFR;T(0.046)PKDS(0.953)PGIPPSAGAHQLFR;T(0.156)PKDS(0.844)PGIPPSAGAHQLFR 92.633 0.00036515 76805400.0 85633.9 87614.3 138036.0 211865.0 262127.0 235259.0 202000.0 204066.0 201792.0 141922.8 True False 100130.02792337918 96312.06868126322 141327.30174444514 199994.89092559763 210765.09604441444 222921.60389020015 182865.09764664606 198709.48372579933 204742.82624704228 167652.28017973364 0.5972482319717548 0.5744751492673449 0.8429787032597081 1.192914827708819 1.2571561556959512 1.329666400309106 1.0907402956321461 1.1852477253084208 1.2212349633869892 1.0 17.355112579290093 -5.571357517277425 2.58480698695222 1.1982067975429154 0.5864321644608249 0.88653435046817 0.08673065795871797 0.08100788057863441 1.0850263900524277 0.02478437959001628 0.053408054255870724 2.6831347422950324e-06 5.571357517277425 -0.6117746330820905 TPKDS(ph)PGIPPSAGAHQLFR ddPTM_PC-9_Lapatinib_30min_R1 3 TPKDSPGIPPSAGAHQLFR 19 1 E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2;Q5SVM6 E9PGT3 RPS6KA1 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 T(0.242)PKDS(0.758)PGIPPSAGAHQLFR;T(0.151)PKDS(0.849)PGIPPSAGAHQLFR;T(0.02)PKDS(0.98)PGIPPSAGAHQLFR 114.06 3.446e-05 99439000.0 197026.0 121905.0 247930.0 161924.0 209785.0 234321.0 142963.0 167718.0 248181.0 139560.0 True False 194216.37310985694 121622.73646232061 227546.1524374767 173832.4311226291 197445.85875317885 224299.63705892977 150364.92461666878 175510.7905646617 220228.2423182101 163682.76004798923 1.186541411281895 0.7430393795086466 1.3901656617395974 1.062008186272422 1.2062715627185832 1.3703314691979083 0.9186362972654184 1.0722619200287475 1.3454577760885913 1.0 17.32054285181973 -5.2614959426110275 24.999999999841965 1.1687467111856795 0.9647904172551532 0.16936401003967738 0.182312330711737 8.313106086531086 3676253.946704641 0.045213735777730406 0.104957772106604 5.476512173603819e-06 5.2614959426110275 -0.20395629393052628 TPKDS(ph)PGIPPSANAHQLFR ddPTM_PC-9_AZD4547_30min_R2 1 TPKDSPGIPPSANAHQLFR 19 1 B4DG22;B1AXG1;B7ZB17;P51812 B4DG22 RPS6KA3 Ribosomal protein S6 kinase alpha-3 1 T(0.018)PKDS(0.982)PGIPPSANAHQLFR 69.07 0.0037736999999999996 7179000.0 17596.0 17214.0 37018.0 64530.0 51136.0 43147.0 31715.0 52781.0 34552.0 42435.0 True False 23191.1619804634 22778.08886188286 36527.117132868494 49653.60547856159 44036.64907161082 40449.011269193754 34537.57355990401 44624.90923672011 36378.34818069394 40949.36356620876 0.5663375437561292 0.5562501313373095 0.8920069557078664 1.212561103624466 1.0753927591673162 0.9877811947869223 0.8434214979693669 1.0897583100301074 0.8883739577997543 1.0 15.321553409266537 -5.348709008253826 3.74856453155938 1.0140530913233297 0.5565482703293761 0.7645622583966025 0.09870531387042301 0.10495582047485308 2.7334495692266585 0.027452215324394486 0.06442047805956817 4.480133875014058e-06 5.348709008253826 -0.4575048209939535 TPKDS(ph)PGIPPSANAHQLFR ddPTM_PC-9_Lapatinib_30min_R1 1 TPKDSPGIPPSANAHQLFR 19 1 B4DG22;B1AXG1;B7ZB17;P51812 B4DG22 RPS6KA3 Ribosomal protein S6 kinase alpha-3 1 T(0.095)PKDS(0.901)PGIPPS(0.004)ANAHQLFR 55.907 0.014094999999999998 6177800.0 41338.0 23309.0 49596.0 27058.0 34742.0 26987.0 17020.0 19980.0 28389.0 18302.0 True False 40748.51253953924 23255.02944260068 45518.40832609639 29047.935582841972 32698.54386540004 25832.82891976961 17901.21232050041 20908.343740576045 25191.531870576986 21465.476314117914 1.8983278984002236 1.083368899077528 2.120540334628344 1.353239739839225 1.5233085624051166 1.2034593848159463 0.8339536499698693 0.9740451800188826 1.1735836420274743 1.0 14.389730565770622 -6.822741874855111 2.231447097320847 0.9908385281167417 1.6018984692656713 0.5213512794319539 0.27386694247760923 0.24489471673164198 2.4998159884700537 0.10396583089396656 0.0921301781512863 1.5040356317508177e-07 6.822741874855111 0.6110599411489296 TPLALAGS(ph)PTPK ddPTM_PC-9_AZD4547_30min_R2 1 TPLALAGSPTPK 12 0 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 T(0.004)PLALAGS(0.955)PT(0.041)PK 124.81 0.00031141 55173000.0 173770.0 163180.0 184120.0 200670.0 207940.0 199710.0 193930.0 213410.0 194670.0 199530.0 True False 229025.24535946388 215924.7438411783 181678.44849812903 154408.6318205944 179071.1203056706 187222.10212924844 211189.39430780968 180432.38817393483 204959.85877331835 192544.51543220543 1.1894664714046517 1.1214276519717592 0.9435659493614487 0.8019373155033408 0.930024518764967 0.9723574920271827 1.0968341208460393 0.9370944052543774 1.0644803790606248 1.0 17.554832503458748 -5.1412790068225975 3.865427725518097 0.9636594251634788 1.1751032347371917 0.4966797031799187 0.07637102630098982 0.19976863300392358 5.121196597969868 0.021453793977718596 0.06713251915993888 7.22305618694323e-06 5.1412790068225975 0.2114438095737129 TPLALAGS(ph)PTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPLALAGSPTPK 12 0 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 TPLALAGS(0.994)PT(0.006)PK 146.67 0.00012601 8671900.0 51398.0 62502.0 60745.0 70089.0 75928.0 64698.0 93119.0 68107.0 67869.0 64365.0 True False 60098.666243226646 68706.78549867221 62193.39117669538 66162.14056160398 61050.45345370856 61305.12298568029 84298.09419682209 66319.26341533157 68861.45572946654 76033.86498694048 0.7904197196019057 0.9036339992774698 0.8179696137685185 0.870166741792857 0.8029376576370876 0.806287080055841 1.1086914260020988 0.8722332269538385 0.905668227457517 1.0 16.214354508195704 -7.199791874245384 24.999972002423124 0.9610026655983429 0.8349523215620882 0.5110788366593686 0.06659592840079726 205.71619294231942 83424.18991049881 0.024935562704105057 0.019314999307404313 6.312597889036131e-08 7.199791874245384 -0.1260503440362547 TPLALAGS(ph)PTPK ddPTM_PC-9_Lapatinib_30min_R1 1 TPLALAGSPTPK 12 0 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 T(0.001)PLALAGS(0.903)PT(0.096)PK 111.07 0.0011167999999999998 33880000.0 98349.0 111690.0 119820.0 121140.0 149670.0 140480.0 141090.0 138690.0 144820.0 131140.0 True False 96946.52522500217 111431.38866721309 109968.86211857523 130049.03971119346 140866.70486254172 134471.9978748744 148394.94984132814 145134.04371273745 128508.84657779272 153807.37426693403 0.6303112948066498 0.7244866457041452 0.7149778262758931 0.8455318890334362 0.9158644410512226 0.8742883656637754 0.964810371080046 0.9436091371071459 0.8355181095203179 1.0 17.230765149149384 -5.752517569025046 1.1423269979717456 0.9269368154309496 0.6509521909468403 0.8348494079665896 0.046618390105842476 0.20845061434292644 0.5264189853605885 0.016507707789630132 0.04593833448777581 1.768000693277853e-06 5.752517569025046 -0.2759846244841093 TPLALAGS(ph)PTPKNPEDK ddPTM_PC-9_AZD4547_30min_R2 1 TPLALAGSPTPKNPEDK 17 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 T(0.005)PLALAGS(0.981)PT(0.014)PKNPEDK 63.93600000000001 0.011239 4622600.0 24323.0 18556.0 23599.0 38039.0 36886.0 29527.0 24310.0 23569.0 19554.0 34646.0 True False 32057.208050171135 24553.86411764254 23286.06184068732 29269.69624669152 31765.01559870613 27680.672022283936 26473.542905289814 19926.952611740122 20587.58451971781 33433.05408542167 0.9588477309989318 0.734418819618072 0.6964981955041044 0.8754718061923765 0.9501081031229247 0.827943266910634 0.7918374085014711 0.5960254950333472 0.6157853382797874 1.0 15.028987529677918 -7.536659969056589 24.023127969453277 0.7023294611109138 0.8335892363925941 0.0951195119497168 0.1292591415094956 268.22785255566555 467559.60300919163 0.06013980616869482 0.03474735784723179 2.9062972498599557e-08 7.536659969056589 0.1312597752816803 TPLALAGS(ph)PTPKNPEDK ddPTM_PC-9_Lapatinib_30min_R1 1 TPLALAGSPTPKNPEDK 17 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 T(0.015)PLALAGS(0.782)PT(0.203)PKNPEDK 54.271 0.026485 3877600.0 38453.0 19918.0 19094.0 24771.0 20821.0 19108.0 14794.0 14255.0 23293.0 17417.0 True False 37904.65316858345 19871.881094758282 17524.16502497146 26592.741973633598 19596.34971566098 18290.79538292356 15559.960932402064 14917.339340436014 20669.497053835974 20427.5052433063 1.855569376539706 0.9728001955241165 0.8578710330138718 1.3018105567417504 0.9593119415344332 0.8954003518817895 0.7617161639207394 0.7302575210609303 1.0118463712356147 1.0 14.318225401883929 -4.761777697944892 5.872161327491692 0.9344818190367309 1.891963490609794 0.769284919763442 0.14992810135209664 0.06832346162331274 8.63826811833615 0.04015384609827826 0.2642082867492117 1.730702025927455e-05 4.761777697944892 0.9574816715730631 TPLALAGSPT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 TPLALAGSPTPK 12 0 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 TPLALAGS(0.471)PT(0.529)PK 113.76 0.0019562 50033000.0 163900.0 158900.0 175910.0 166320.0 182090.0 190780.0 198960.0 202390.0 165230.0 204070.0 True False 216016.79066821674 210261.31754114016 173577.31846244767 127977.4936183848 156809.94660219076 178850.49644092974 216667.0545634086 171115.2759595269 173963.72047626963 196925.5714140741 1.0969463697225976 1.0677197279728852 0.8814361548682156 0.6498774775637816 0.7962904232100336 0.9082136725903512 1.1002484492368145 0.8689337536552016 0.8833983277391501 1.0 17.587290936397018 -5.247236650186448 5.6142817169124415 0.8778212366023892 1.0856070975499632 0.330355768368618 0.11147845893117501 0.2000113176090302 23.3174170636159 0.031806349502404206 0.08028437895427135 5.659308252272145e-06 5.247236650186448 0.207785860947574 TPLALAGSPT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPLALAGSPTPK 12 0 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 TPLALAGS(0.327)PT(0.672)PK 118.24 0.0014521 8652000.0 53390.0 62345.0 50806.0 56813.0 71132.0 56619.0 78208.0 63900.0 48267.0 50352.0 True False 62427.87249943325 68534.199576249 52017.40772282798 53629.95180023118 57194.19522533444 53649.799967946994 70799.57206311326 62222.69270764646 48972.81356280724 59480.41901378732 1.0495533409904647 1.152214471797232 0.8745299475911653 0.9016404505792062 0.9615634216039577 0.9019741430454816 1.1903004927840573 1.0461038059133962 0.8233434527664565 1.0 15.860127190137222 -5.2500087010890795 24.834949729372756 0.9678553362001446 1.1008839071457694 0.23286098175881664 0.10013254220502421 1093.3481383344142 2375459.550241098 0.026731886206870902 0.06938641190947827 5.62330058795881e-06 5.2500087010890795 0.1330285709456248 TPLCATAPCLPS(ph)PTATR ddPTM_PC-9_AZD4547_30min_R2 2 TPLCATAPCLPSPTATR 17 0 Q6PI47-3;Q6PI47 Q6PI47-3 KCTD18 BTB/POZ domain-containing protein KCTD18 1 TPLCATAPCLPS(0.925)PT(0.065)AT(0.009)R;TPLCATAPCLPS(0.817)PT(0.067)AT(0.115)R 132.5 2.3893000000000003e-05 8985800.0 14408.6 18030.1 17833.1 24767.0 26516.0 21205.1 15287.5 23435.8 16112.4 21123.0 True False 18990.23508250199 23857.977227177566 17596.621442059455 19057.35079633558 22834.711099476535 19879.141744834662 16648.057884188303 19814.335611108636 16964.068569883468 20383.490199340824 0.9316478628922985 1.1704559422286327 0.8632781368633575 0.9349405136197858 1.1202552102787078 0.9752570119457524 0.8167422615743539 0.9720776676287463 0.8322455283164443 1.0 14.315113480227248 -7.0154642762105714 24.13515451902817 0.9019480773028258 1.0062959852757372 0.18276512915655618 0.0988453652221397 737.68760754456 1151309.97394515 0.036071924985232935 0.028895961510682595 9.650186881458653e-08 7.0154642762105714 0.10434790797291138 TPLCATAPCLPS(ph)PTATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPLCATAPCLPSPTATR 17 0 Q6PI47-3;Q6PI47 Q6PI47-3 KCTD18 BTB/POZ domain-containing protein KCTD18 1 TPLCATAPCLPS(0.945)PT(0.041)AT(0.014)R;TPLCATAPCLPS(0.868)PT(0.126)AT(0.006)R 114.58 0.0017655000000000001 0.0 10647.3 10464.4 14422.7 15991.3 14718.1 16464.0 14873.0 13815.3 12163.9 10294.099999999999 True False 12449.67759623929 11503.236475189684 14766.591866394334 15095.359305494097 11834.19395976489 15600.598856784458 13464.121768804785 13452.663013520312 12341.774025662064 12160.338841949231 1.0237936424346938 0.945963482161142 1.2143240462555511 1.2413600888669316 0.973179622178023 1.2829082363204751 1.1072160030901381 1.1062736974987062 1.014920240798467 1.0 13.569895808889255 -8.27493000160897 3.4299547251282543 1.0002080905452795 1.115921025813272 0.1361643040158813 0.10541735420487468 0.49576281257157173 11.664060402875794 0.09761617609208177 0.027921835050188852 5.309700176227466e-09 8.27493000160897 0.11571293526799242 TPLCATAPCLPS(ph)PTATR ddPTM_PC-9_Lapatinib_30min_R1 2 TPLCATAPCLPSPTATR 17 0 Q6PI47-3;Q6PI47 Q6PI47-3 KCTD18 BTB/POZ domain-containing protein KCTD18 1 TPLCATAPCLPS(0.941)PT(0.054)AT(0.004)R;TPLCATAPCLPS(0.981)PT(0.015)AT(0.004)R 144.25 6.442600000000001e-05 6938600.0 22422.0 23534.9 26655.0 24730.3 24102.0 27504.0 26550.0 25668.0 27586.0 21888.5 True False 22102.258168308792 23480.40638502993 24463.528791275476 26549.04875986238 22684.36774635518 26327.718034955502 27924.629089852282 26860.628985640942 24478.97418654184 25671.898060407075 0.8609514620345263 0.914634606673006 0.9529302716032817 1.0341677384894306 0.8836264343593875 1.0255462207354227 1.0877508559805136 1.0463047540324728 0.9535319176222096 1.0 14.647902345548667 -3.696761385002152 0.4734329060004253 1.0213092245949376 0.4687363879326146 0.4575321177369036 0.052296887204389325 11.584984461858287 0.9096047319885131 0.03393867416594818 4.452622096117485 0.00020101969744617217 3.696761385002152 -0.552572836662323 TPLDLFAHFGPEPGDHSDPLPPSAPS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 4 TPLDLFAHFGPEPGDHSDPLPPSAPSPTR 29 0 Q8N1G0;Q8N1G0-2;F8WCX2 Q8N1G0 ZNF687 Zinc finger protein 687 1 TPLDLFAHFGPEPGDHS(0.001)DPLPPS(0.176)APS(0.743)PT(0.08)R;TPLDLFAHFGPEPGDHSDPLPPS(0.099)APS(0.728)PT(0.173)R;TPLDLFAHFGPEPGDHSDPLPPS(0.089)APS(0.669)PT(0.242)R;TPLDLFAHFGPEPGDHSDPLPPS(0.04)APS(0.694)PT(0.265)R 95.316 8.179000000000001e-11 53709300.0 33682.2 40083.5 54508.5 49071.700000000004 48834.200000000004 62869.2 45804.5 57910.1 50856.6 50468.5 True False 44392.43896671766 53039.70749943545 53785.681674778774 37758.977715207344 42054.414269650704 58937.978985449685 49881.01176492585 48961.42468671273 53544.77605019331 48701.61317641586 0.9115188609032574 1.0890749615891644 1.1043921990827381 0.7753126693859173 0.8635117304495343 1.21018535406525 1.024216827977294 1.0053347618970183 1.099445635532311 1.0 15.571681940010457 -6.743291284376297 24.99832160782053 1.0654437812116098 0.9555673180606331 0.23494051587694276 0.1070426738853956 439.10265037287 604846.5931171353 0.03792128635992376 0.0378485921955206 1.805962447947053e-07 6.743291284376297 -0.10987646315097666 TPLDLFAHFGPEPGDHSDPLPPSAPS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPLDLFAHFGPEPGDHSDPLPPSAPSPTR 29 0 Q8N1G0;Q8N1G0-2;F8WCX2 Q8N1G0 ZNF687 Zinc finger protein 687 1 TPLDLFAHFGPEPGDHSDPLPPS(0.257)APS(0.656)PT(0.087)R 55.925 0.001973 11790000.0 5314.0 7778.5 9270.6 4725.0 6982.2 5726.5 5289.7 6238.7 6424.7 2973.3 True False 6213.555243715834 8550.698073684387 9491.646262946282 4460.273568656685 5614.08803214208 5426.192259072894 4788.62132188843 6074.940735449043 6518.64908316174 3512.3357533701524 1.7690664218971124 2.4344762784935443 2.70237441105648 1.2698881547349135 1.5983916192394922 1.5448956592109282 1.363372313507801 1.7296013712869058 1.8559299397578872 1.0 11.778215047123428 -5.767729885435085 24.999948941016147 1.5134373872136262 2.315222790242265 0.5898687459471852 0.3130629643078128 101.18280184665232 402125.8744394669 0.08698769005222375 0.1326854729501491 1.7071438370823776e-06 5.767729885435085 0.8017854030286387 TPLGAS(ph)LDEQSSSTLK ddPTM_PC-9_AZD4547_30min_R2 3 TPLGASLDEQSSSTLK 16 0 E9PHV5;P28290-3;P28290 E9PHV5 SSFA2 Sperm-specific antigen 2 1 T(0.028)PLGAS(0.972)LDEQSSSTLK;T(0.014)PLGAS(0.967)LDEQS(0.017)S(0.002)STLK;T(0.001)PLGAS(0.678)LDEQS(0.237)S(0.032)S(0.032)T(0.021)LK 192.72 3.0785e-09 218040000.0 103489.7 99881.9 102053.1 125343.0 178018.0 130597.1 67783.1 115523.1 112048.9 109180.3 True False 136397.27188051614 132166.77087798878 100699.80921368893 96447.10788004556 153303.27351435422 122430.8426918216 73815.66458673576 97671.65935174687 117971.576101637 105357.93092889719 1.2946084901056614 1.2544548826341706 0.9557876500217921 0.9154233291192357 1.4550710341665107 1.1620467639445804 0.7006180164695116 0.9270461036071642 1.1197218383232332 1.0 16.684939393064056 -7.0905443033321225 17.229211435487745 0.9308092628389502 1.1684387049627427 0.3022561815223015 0.17555353491560202 6.079502525378145 1153.6782099064155 0.07069767028572899 0.054762452557682265 8.118124299459081e-08 7.0905443033321225 0.23762944212379256 TPLGAS(ph)LDEQSSSTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TPLGASLDEQSSSTLK 16 0 E9PHV5;P28290-3;P28290 E9PHV5 SSFA2 Sperm-specific antigen 2 1 TPLGAS(1)LDEQSSSTLK;TPLGAS(1)LDEQSSSTLK;TPLGAS(1)LDEQSSSTLK;T(0.137)PLGAS(0.863)LDEQSSSTLK 156.17 1.9367e-05 129901600.0 93741.0 69847.0 85943.2 71721.0 100356.0 85928.0 73684.1 82296.0 64934.6 62232.1 True False 109609.4998308556 76780.9485572581 87992.41182940119 67702.70489261921 80691.96221157379 81421.78441240119 66704.20862131308 80135.81719981959 65884.14568080597 73514.28710096744 1.4909958887353905 1.0444357360332435 1.1969430065825015 0.920946220965642 1.0976364648785648 1.1075640888766733 0.907363877850014 1.0900713366064188 0.8962087272956626 1.0 16.16573703666412 -2.2709635968609554 1.1699741063283688 1.0195821944260373 199.9999999437437 0.6781791997558249 0.094940112318222 369.47209887296015 1.56871803029757 0.02662934882208592 196061.71673842642 0.0053584157058157705 2.2709635968609554 198.98041774931764 TPLGAS(ph)LDEQSSSTLK ddPTM_PC-9_Lapatinib_30min_R1 3 TPLGASLDEQSSSTLK 16 0 E9PHV5;P28290-3;P28290 E9PHV5 SSFA2 Sperm-specific antigen 2 1 T(0.004)PLGAS(0.996)LDEQSSSTLK;TPLGAS(1)LDEQSSSTLK;TPLGAS(0.998)LDEQS(0.002)SSTLK 213.36 6.8967e-22 153913300.0 79916.0 57417.5 82684.0 82235.0 76908.4 74384.0 64258.9 62813.9 94033.0 77419.8 True False 78776.38318520035 57284.553306470676 75886.04068947009 88282.83622791829 72384.79911973211 71202.76971757312 67585.91142078757 65732.4631074159 83442.01332861194 90801.70927460113 0.8675649810397954 0.630875274971219 0.8357336144408547 0.9722596296170449 0.7971744111206884 0.784156711216116 0.7443242198932103 0.7239121777832265 0.9189476056697113 1.0 16.470431834981724 -8.481032871019629 4.827113802289665 0.999454270717649 0.7949498107539059 0.38952851510727415 0.08553849875628977 0.1841252097403937 10.176034054997954 0.08609666804795352 0.02242434715578916 3.3034453686761806e-09 8.481032871019629 -0.2045044599637431 TPLLS(ph)SLSATSNNSTVACIDR ddPTM_PC-9_Lapatinib_30min_R1 1 TPLLSSLSATSNNSTVACIDR 21 0 P00533;E9PFD7;Q504U8 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 TPLLS(0.602)S(0.389)LS(0.008)ATSNNSTVACIDR 257.72 3.1086999999999994e-73 8564100.0 15086.0 15947.0 6232.5 5815.4 14064.0 7756.0 10930.0 5395.3 16248.0 8697.1 True False 14870.870873566417 15910.075701280763 5720.087908145731 6243.0839156057045 13236.783170887862 7424.2939601190665 11495.901919099266 5645.985334511007 14417.97914097484 10200.38214684269 1.4578738972215248 1.5597529065325642 0.5607719226398064 0.6120441200860418 1.297675222392038 0.727844687898982 1.1270069840135917 0.5535072366145224 1.4134744104109487 1.0 13.316335581846943 -5.243356912597545 24.692306969100066 0.8998232850653298 1.508813564525635 0.40519816494750327 0.28917907014889915 647.2009723605485 883773.9477648224 0.07010197135157344 0.1846326888444628 5.710091761019516e-06 5.243356912597545 0.6089902794603053 TPLLSSLS(ph)ATSNNSTVACIDR ddPTM_PC-9_AZD4547_30min_R2 2 TPLLSSLSATSNNSTVACIDR 21 0 P00533;E9PFD7;Q504U8 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 TPLLSS(0.003)LS(0.992)AT(0.002)S(0.002)NNSTVACIDR;TPLLS(0.001)S(0.009)LS(0.809)AT(0.087)S(0.087)NNS(0.003)T(0.003)VACIDR 166.21 2.3042e-08 27378000.0 22763.8 29193.0 38429.0 44586.0 33729.0 21926.0 48159.0 75582.0 64106.0 34189.0 True False 30002.214883545847 38629.06634977037 37919.40635093746 34307.386546833215 29046.310554919473 20554.963753872627 52445.05770365496 63902.53860157598 67494.51228500725 32992.053516321714 0.9093770070633298 1.1708597141629857 1.1493496860441896 1.039868177040292 0.8804032322677272 0.6230277161651592 1.589626959040592 1.9369069757953181 2.0457808802842963 1.0 15.009830957561771 -7.412108146226368 5.775172218498441 1.7469975794720116 0.9822381208896307 0.5482717682219889 0.2995840702715416 0.16095875679358138 7.179449343051842 0.12579772987903406 0.08352294885029393 3.871612236207281e-08 7.412108146226368 -0.7647594585823809 TPLLSSLS(ph)ATSNNSTVACIDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPLLSSLSATSNNSTVACIDR 21 0 P00533;E9PFD7;Q504U8 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 TPLLS(0.002)S(0.031)LS(0.967)ATSNNSTVACIDR;TPLLSS(0.001)LS(0.987)AT(0.006)S(0.006)NNSTVACIDR 166.29 2.2801e-08 14363800.0 22709.7 15574.6 15472.5 10151.9 32620.8 16877.3 20102.0 34788.2 22662.2 21293.7 True False 26554.003672979565 17120.743359054435 15841.42307978302 9583.121955903871 26228.988410372152 15992.224677211374 18197.793034123155 33875.046611144724 22993.591802329756 25154.079249163555 1.0556539720634999 0.6806348659978778 0.6297755096843703 0.3809768531369534 1.0427329957324651 0.6357706246688859 0.723452957823065 1.3467019116699002 0.9141098576722644 1.0 14.6185047611038 -7.73295970259308 24.430596322462307 1.0978043030103375 0.72372610265489 0.3627527104104912 0.21286093428584457 157.62016628343468 135210.65226081214 0.0984759867300365 0.056839759365878435 1.849440217261221e-08 7.73295970259308 -0.3740782003554475 TPLLSSLS(ph)ATSNNSTVACIDR ddPTM_PC-9_Lapatinib_30min_R1 1 TPLLSSLSATSNNSTVACIDR 21 0 P00533;E9PFD7;Q504U8 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 TPLLS(0.001)S(0.086)LS(0.912)AT(0.001)S(0.001)NNSTVACIDR 184.97 5.3759e-15 8170200.0 32096.0 29108.0 13778.0 7791.1 22231.0 16060.0 19845.0 10916.0 32626.0 13569.0 True False 31638.305154314483 29040.602214390183 12645.22602461803 8364.083484347697 20923.416287827633 15373.151237688531 20872.47699766925 11423.197210817225 28951.31631298898 15914.383570443992 1.988032085205787 1.8248022039838259 0.7945784370877297 0.5255675438086949 1.3147487739761632 0.9659909961099197 1.3115479405959132 0.717790743213721 1.8191918137977414 1.0 13.95804365609056 -5.187279624971888 5.906111674671092 1.0431032478833495 1.9315633026233914 0.49108619065848447 0.3465608726711453 0.17909189810878914 10.978745132726939 0.08616499085083741 0.2354501087707062 6.497112323795845e-06 5.187279624971888 0.8884600547400419 TPLLSSLSAT(ph)SNNSTVACIDR ddPTM_PC-9_AZD4547_30min_R2 1 TPLLSSLSATSNNSTVACIDR 21 0 P00533;E9PFD7;Q504U8 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 TPLLSSLS(0.001)AT(0.489)S(0.489)NNS(0.016)T(0.004)VACIDR 135.81 0.00017528 5891000.0 15160.0 27008.0 25265.0 33073.0 32730.0 22061.0 24732.0 33383.0 25899.0 21424.0 True False 19980.564652411063 35737.80782977419 24929.969592142268 25448.530822756355 28186.00446092425 20681.522182531433 26933.10008776747 28224.424415024845 27267.968266143573 20673.952280958096 0.9664608092771075 1.728639369197479 1.2058637484185455 1.2309465784244806 1.363358301203258 1.0003661564789579 1.3027552604237367 1.3652166761079918 1.3189528492459057 1.0 14.335526597586076 TPLLSSLSATS(ph)NNSTVACIDR ddPTM_PC-9_AZD4547_30min_R2 1 TPLLSSLSATSNNSTVACIDR 21 0 P00533;E9PFD7;Q504U8 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 TPLLSSLSAT(0.006)S(0.992)NNS(0.002)TVACIDR 254.8 4.991899999999999e-73 5422900.0 15655.0 34171.0 24960.0 30956.0 31030.0 22013.0 19311.0 32409.0 23060.0 19690.0 True False 20632.96435577145 45216.10749967467 24629.014091425714 23819.572465432393 26722.020116788237 20636.52363011941 21029.641589636023 27400.933734731483 24278.90452207696 19000.659093169565 1.0859078232285466 2.3797125814403532 1.2962189348620783 1.2536182218013243 1.4063733255650264 1.086095146959292 1.1067848481738112 1.4421043817675612 1.2777927546105408 1.0 14.213761843050682 -5.485333785160269 24.949254375863482 1.2426729633715061 1.7590993150008976 0.28382266338877316 0.3175128136505421 591.8416715357367 393287.68151985295 0.07631976629398862 0.15880738468945224 3.2708920771025772e-06 5.485333785160269 0.5164263516293914 TPLLSSLSATS(ph)NNSTVACIDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPLLSSLSATSNNSTVACIDR 21 0 P00533;E9PFD7;Q504U8 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 TPLLSSLSAT(0.034)S(0.954)NNS(0.01)T(0.002)VACIDR;TPLLSSLSAT(0.034)S(0.928)NNS(0.019)T(0.019)VACIDR 165.17 2.7466e-25 0.0 10397.099999999999 9369.2 5867.9 10739.400000000001 21996.1 10951.300000000001 11830.8 12818.3 12013.0 10730.3 True False 12157.123677914547 10299.31225711432 6007.812990134672 10137.706235604575 17686.122105325026 10376.994549338166 10710.100976425445 12481.833207111507 12188.667398636822 12675.618448991943 0.9590951105727997 0.8125293687688584 0.4739660644023611 0.799780008872924 1.3952867212354088 0.8186578501945535 0.844937153916714 0.9847119694664013 0.9615836456173981 1.0 13.629768518220049 -6.019107956893446 24.99637201706319 0.9935866258713628 0.7352538909176795 0.29018002826185907 0.18426923500845085 977.1990144153431 1278338.4041891599 0.05556569287993945 0.07293709837371827 9.569561616272313e-07 6.019107956893446 -0.25833273495368336 TPLLSSLSATS(ph)NNSTVACIDR ddPTM_PC-9_Lapatinib_30min_R1 1 TPLLSSLSATSNNSTVACIDR 21 0 P00533;E9PFD7;Q504U8 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 TPLLSSLSAT(0.048)S(0.948)NNS(0.004)T(0.001)VACIDR 199.36 3.3461999999999995e-19 3466300.0 17118.0 14505.0 5296.4 4898.2 6799.8 7721.6 7121.5 5351.1 8367.9 4179.2 True False 16873.89418094326 14471.414563684539 4860.950436695233 5258.429967916196 6399.849132921161 7391.365167928749 7490.216424232879 5599.731641150975 7425.418984106562 4901.569151566036 3.4425494487927613 2.952404447677937 0.9917131201019931 1.07280542318497 1.305673537396984 1.5079589697448683 1.5281262372560382 1.1424365275682946 1.5149065033050004 1.0 12.259027961397061 -5.175718032245345 4.433817567647566 1.2769686856482765 3.3146607400301464 0.9310627559493452 0.2121336409324339 0.05163398508168537 1.798096103909144 0.05719068696619186 0.16577358902506878 6.672398372454406e-06 5.175718032245345 2.03769205438187 TPLLSSLSATSNNS(ph)TVACIDR ddPTM_PC-9_Lapatinib_30min_R1 1 TPLLSSLSATSNNSTVACIDR 21 0 P00533;E9PFD7;Q504U8 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 TPLLSSLSAT(0.002)S(0.328)NNS(0.335)T(0.335)VACIDR 214.34 8.393699999999999e-80 0.0 14967.0 16999.0 8091.9 3718.2 6223.2 5759.3 5831.7 4934.1 7429.6 2572.8 True False 14753.567835388349 16959.639859915445 7426.6152176372925 3991.6488315515917 5857.163611281947 5512.988164584031 6133.636891272754 5163.35629881763 6592.800210843592 3017.5050519594906 4.889326639505627 5.620418049972208 2.461177393162818 1.3228308694825603 1.9410617415465319 1.8270021324418455 2.032684878949822 1.7111342681811512 2.184851424378692 1.0 11.55914047102956 -5.3469206838389995 4.1360571608761525 1.7831892917978405 5.265965587743008 0.9291366421947914 0.3838151179490973 0.04549153404721867 1.4115572823568572 0.0952969346231741 0.21693435572422878 4.498620066837327e-06 5.3469206838389995 3.4827762959451674 TPLQESLIELSDSS(ph)LSK ddPTM_PC-9_AZD4547_30min_R2 1 TPLQESLIELSDSSLSK 17 0 A0A087WYA1;Q9UKN7;A0A2R8Y712;Q9UKN7-2;G3V4Q3;K7EQV1;G3V4G3 A0A087WYA1 MYO15A Unconventional myosin-XV 1 TPLQES(0.002)LIELS(0.161)DS(0.161)S(0.547)LS(0.128)K 50.397 0.046116000000000004 4769400.0 16839.0 10124.0 27142.0 43236.0 35913.0 26976.0 20182.0 32978.0 16143.0 33716.0 True False 22193.451727041545 13396.385014389583 26782.079345732243 33268.60818954114 30927.099853503576 25289.186455553605 21978.15890228543 27882.007859050722 16996.286023412315 32535.613102351697 0.6821279702713635 0.41174527654502024 0.8231619690546547 1.0225290079791507 0.9505614587993777 0.777277083299398 0.6755108266485021 0.8569688781133001 0.5223902180648875 1.0 14.989732119738095 -5.281421612809422 23.714086043133904 0.8274302390324123 0.546936664320911 0.3466910685554895 0.154626508738339 406.6310829330659 482572.88420729275 0.041109231426973786 0.08579823030299089 5.230923722659493e-06 5.281421612809422 -0.28049357471150127 TPLS(ph)PSPMK ddPTM_PC-9_AZD4547_30min_R2 1 TPLSPSPMK 9 0 Q69YQ0-2;Q69YQ0;F8WAN1;A0A494C1J1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 T(0.188)PLS(0.812)PS(0.001)PMK 85.958 0.012033 2720500.0 30785.0 25903.0 33398.0 50880.0 47496.0 38256.0 27804.0 40051.0 32957.0 33939.0 True False 40573.989632221266 34275.638189226935 32955.12069813447 39150.40208816387 40902.00024063725 35863.84627237762 30278.502136514908 33862.03823042149 34699.03973695101 32750.805940227612 1.2388699596056196 1.046558617573633 1.0062384650405167 1.1954027073292774 1.248885304236058 1.0950523275009327 0.9245116652022297 1.03392992197572 1.0594865909644804 1.0 14.999242788845741 -7.011778420924655 24.515326496940123 1.0076627296816245 1.140000128956903 0.42224719233614594 0.0785319452332634 505.21800406610157 1051548.605343599 0.030995607681140763 0.02542871388206757 9.73243650587788e-08 7.011778420924655 0.13233739927527854 TPLSPS(ph)PMK ddPTM_PC-9_Lapatinib_30min_R1 1 TPLSPSPMK 9 0 Q69YQ0-2;Q69YQ0;F8WAN1;A0A494C1J1 Q69YQ0-2 SPECC1L;SPECC1L-ADORA2A Cytospin-A 1 T(0.142)PLS(0.202)PS(0.656)PMK 65.719 0.044363 48770000.0 63546.0 67384.0 68789.0 58926.0 87360.0 94198.0 99069.0 108250.0 110870.0 87480.0 True False 62639.82238709082 67227.97648806054 63133.433953218875 63259.61461137352 82221.65655636833 90169.37112626294 104198.30807166014 113279.69018605398 98382.65308714187 102600.80144022698 0.6105198157110248 0.6552383172876687 0.6153308070405187 0.616560628410171 0.8013744084081925 0.8788369082944608 1.0155701184494532 1.1040819232981167 0.9588877640927346 1.0 16.646682474673447 -6.7201679788655255 1.4212229183060248 1.030653274140662 0.620955389792665 0.9447490798700103 0.0425985829190559 0.08337531616971351 0.3515321589989654 0.019174887962676482 0.01797362899417091 1.90472385564884e-07 6.7201679788655255 -0.40969788434799703 TPLSQS(ph)MSVLPTSKPEK ddPTM_PC-9_AZD4547_30min_R2 3 TPLSQSMSVLPTSKPEK 17 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 T(0.056)PLS(0.056)QS(0.635)MS(0.253)VLPTSKPEK;T(0.048)PLS(0.281)QS(0.47)MS(0.201)VLPTSKPEK;T(0.003)PLS(0.021)QS(0.488)MS(0.488)VLPTSKPEK 62.303000000000004 0.014315999999999999 85532000.0 99892.0 121515.0 189076.0 195859.0 138998.0 152763.0 181667.0 136131.0 128770.0 163044.0 True False 131655.57811732465 160792.34739466116 186568.72869993642 150706.7335413852 119700.5269801268 143210.70546077003 197835.0110643883 115095.08192917814 135576.51931083456 157335.87918673138 0.8367803885410745 1.0219687221109148 1.185799003153696 0.9578662814889255 0.7607961235470155 0.9102228061458433 1.2574055713610701 0.7315247006855919 0.8617012216897323 1.0 17.26348817775419 -5.991218258287192 24.987780719684938 0.9173984775776206 1.0249398586443936 0.0666639530345714 0.1568258098470522 541.7045824485945 1541362.8353259324 0.04573992974230345 0.06773585966312533 1.0204265310233904e-06 5.991218258287192 0.10754138106677302 TPLSQS(ph)MSVLPTSKPEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPLSQSMSVLPTSKPEK 17 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 T(0.059)PLS(0.225)QS(0.53)MS(0.185)VLPT(0.001)SKPEK;T(0.001)PLS(0.025)QS(0.777)MS(0.196)VLPT(0.001)SKPEK 67.928 0.025408 57172000.0 67422.0 58924.0 56919.0 77128.0 70476.0 67769.0 78688.0 68847.0 70138.0 61588.0 True False 78835.21295480017 64773.58530485043 58276.16482650955 72806.76821234974 56666.733716199116 64215.07433949371 71234.10298821439 67039.83919942637 71163.6355619402 72753.41686966016 1.0835946454038816 0.890316745135066 0.8010093179666459 1.0007333173476258 0.7788875925610368 0.8826399790203238 0.979116941212979 0.9214665383968175 0.978148362288357 1.0 16.150727385441918 -8.02744641894466 1.1769620768590487 0.9942748613195888 0.9036951227212084 0.10426564205335087 0.08547497481726252 1.0613839746359954 2.6872183083859635 0.07806592667699304 0.027052733447383914 9.387578487204332e-09 8.02744641894466 -0.09057973859838031 TPLSQS(ph)MSVLPTSKPEK ddPTM_PC-9_Lapatinib_30min_R1 2 TPLSQSMSVLPTSKPEK 17 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 T(0.174)PLS(0.174)QS(0.571)MS(0.081)VLPTS(0.001)KPEK;T(0.087)PLS(0.087)QS(0.699)MS(0.127)VLPTSKPEK 77.51 0.0036013000000000004 77254000.0 234123.0 164920.0 167024.0 121292.0 127359.0 125251.0 114505.0 127140.0 128512.0 65240.0 True False 230784.36308710004 164538.13787265462 153291.93145128503 130212.21829825101 119867.9940174278 119894.30670434155 120433.50862273207 133047.38854738954 114037.62526864605 76516.64707316442 3.016132722941015 2.1503573949773958 2.003380144254215 1.701750184815906 1.566560985125384 1.5669048669853485 1.5739517246171908 1.7388031707684604 1.490363595775498 1.0 16.223486036337242 -1.5228787453062076 0.5354755940444497 1.485385239813215 62.260268936222126 0.8698442911238567 0.182130824099525 40.975900567744155 0.3926774725156887 0.08832695376551251 2847.4042469500587 0.029999999998212963 1.5228787453062076 60.774883696408914 up TPLSQSMS(ph)VLPTSKPEK ddPTM_PC-9_AZD4547_30min_R2 1 TPLSQSMSVLPTSKPEK 17 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 T(0.022)PLS(0.1)QS(0.358)MS(0.52)VLPTSKPEK 67.646 0.028172000000000003 36761000.0 52159.0 50811.0 89388.0 85267.0 74335.0 68354.0 91049.0 64943.0 59376.0 64103.0 True False 68744.47702540291 67234.66208673932 88202.65671491831 65610.0105120179 64014.86836549958 64079.81357439618 99152.18461471544 54907.551591677206 62514.49414149355 61858.773481434684 1.1113132892302624 1.0869058389416348 1.4258714124260816 1.0606419561763387 1.0348551185663581 1.0359050134356138 1.602879899396541 0.8876275506522335 1.0106002855076923 1.0 15.916690607903977 TPLSQSMS(ph)VLPTSKPEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPLSQSMSVLPTSKPEK 17 1 Q6WKZ4;E7EX40;Q6WKZ4-2;Q6WKZ4-3 Q6WKZ4 RAB11FIP1 Rab11 family-interacting protein 1 1 T(0.001)PLS(0.002)QS(0.201)MS(0.796)VLPTSKPEK 66.732 0.0093115 9198700.0 18386.0 18302.0 14747.0 21556.0 20013.0 25792.0 27258.0 20719.0 23885.0 22029.0 True False 21498.38665994717 20118.90160629576 15098.62440830894 20348.287205494922 16091.596314522578 24439.422115778947 24675.92490916968 20175.1482035951 24234.27293901942 26022.68331853195 0.8261402714237843 0.7731294025304518 0.5802101275834424 0.7819442352051362 0.6183680644133656 0.9391584187006 0.9482467510026846 0.7752908474748818 0.9312749435705227 1.0 14.667482112194826 -6.773595406377259 24.993327873746313 0.9065906884071282 0.7152588886545558 0.5698174371530715 0.08779909155180378 178.70873348388665 367430.8489219498 0.030746511821385415 0.02731291550311112 1.684242389569297e-07 6.773595406377259 -0.19133179975257242 TPLYLQPDAYGS(ph)LDR ddPTM_PC-9_AZD4547_30min_R2 2 TPLYLQPDAYGSLDR 15 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 TPLYLQPDAYGS(1)LDR;TPLYLQPDAYGS(1)LDR 144.4 0.00010574 51236000.0 12431.6 15886.4 20101.9 29772.0 28437.0 24788.0 19438.5 25081.0 21575.4 20183.2 True False 16384.590206656547 21021.36812451586 19835.33567165186 22908.525372814758 24489.013408350216 23238.00244143914 21168.48884263578 21205.307754043617 22715.831596947923 19476.59231128796 0.841245221175606 1.0793144811237128 1.0184192057126946 1.1762080864391133 1.257356164618039 1.1931246529184265 1.0868682007769528 1.0887586193275582 1.1663144781124062 1.0 14.249453660375105 -4.0973406409214945 1.0844746711766886 1.1402223143691874 6.122378494951316e-16 0.5628346023143405 0.07454723598654162 4.82553695899894 1.6183552851431762 0.023840274559003227 9.052993093483078 7.99207147213202e-05 4.0973406409214945 -1.1402223143691868 TPLYLQPDAYGS(ph)LDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TPLYLQPDAYGSLDR 15 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 TPLYLQPDAY(0.004)GS(0.996)LDR;TPLYLQPDAY(0.006)GS(0.994)LDR;TPLYLQPDAYGS(1)LDR;TPLYLQPDAYGS(1)LDR;TPLYLQPDAYGS(1)LDR 129.43 1.5175999999999998e-05 50453300.0 36517.700000000004 38328.200000000004 46478.8 56925.8 66485.2 56073.8 49277.1 32198.3 41704.6 39683.8 True False 42699.42535254829 42133.17039375071 47587.03086383059 53736.43198193369 53457.90232800154 53133.19121571669 44609.2163526908 31353.12874191884 42314.45087764828 46878.15880321204 0.9108596933551617 0.8987804015644018 1.015121584949492 1.1462999689794071 1.1403584034178975 1.1334316997978184 0.9515991560153643 0.6688216760716839 0.9026474579617862 1.0 15.51662828681731 -7.527437771585236 24.94193857643532 0.8334827821123921 1.0425061108178044 0.34358155884454133 0.11268473097975856 134.92495203050478 738141.6281851172 0.0559664441563375 0.03247337380505258 2.9686720827916297e-08 7.527437771585236 0.2090233287054123 TPLYLQPDAYGS(ph)LDR ddPTM_PC-9_Lapatinib_30min_R1 2 TPLYLQPDAYGSLDR 15 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 TPLYLQPDAYGS(1)LDR;TPLYLQPDAYGS(1)LDR 85.176 0.0058738 42535000.0 42814.0 30939.0 35564.0 29912.0 30993.0 28842.0 26290.0 30751.0 29441.0 29428.0 True False 42203.46450887397 30867.362646386482 32640.065201010006 32111.82826350685 29170.052674582425 27608.494893985826 27651.167562042046 32179.803722044733 26125.044552525884 34514.59058965482 1.2227716970666824 0.894327938389003 0.9456888997777457 0.9303841568131432 0.8451513454523104 0.7999079352330783 0.801144301283702 0.9323536270394034 0.7569275516875589 1.0 15.074918750757776 -1.9937506242015386 1.0884783530486417 0.8610399520294933 199.99999863840387 0.6543950558907601 0.07433505269717783 532.7457102548346 1.4968396716881833 0.02207737436091698 263783.5379180728 0.010144937499589947 1.9937506242015386 199.13895868637437 TPMAGVS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 TPMAGVSPK 9 0 A0A087WWD1;Q9H707;B7Z6K7 A0A087WWD1 ZNF814;ZNF552 Zinc finger protein 552;Putative uncharacterized zinc finger protein 814 1 TPMAGVS(1)PK 70.808 0.032296 12038000.0 64159.0 49344.0 49088.0 50661.0 54422.0 45675.0 40660.0 43018.0 40228.0 41926.0 True False 63244.08089468037 49229.746999686344 45052.174125159676 54386.77894014179 51221.00495776873 43721.58672362538 42765.17584909206 45016.77332492993 35697.09902038008 49172.85323711658 1.286158453928042 1.0011570156869973 0.916200121801219 1.1060326045731599 1.0416520821107482 0.8891407320375609 0.8696907548332403 0.9154801961125664 0.725951346533523 1.0 15.58557444899741 -6.758249651178212 4.150702963365969 0.8717437241863123 1.0620612835129426 0.43647940732043755 0.10806344725859232 0.21368796202293744 8.429121689639437 0.038004234046013594 0.03561396338267119 1.7448188675280048e-07 6.758249651178212 0.1903175593266303 TPMY(ph)GSQTPLQDGSR ddPTM_PC-9_Lapatinib_30min_R1 1 TPMYGSQTPLQDGSR 15 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 T(0.058)PMY(0.922)GS(0.01)QT(0.01)PLQDGSR 65.241 0.035962 6814200.0 14988.0 12088.0 16788.0 12638.0 14252.0 15055.0 13966.0 11859.0 14861.0 10443.0 True False 14774.268371537422 12060.010978684499 15407.755443554046 13567.440679132114 13413.725380510075 14411.132744919103 14689.09114383718 12410.012433407977 13187.197686732343 12248.058635577181 1.20625388978971 0.9846467377004176 1.2579753169044137 1.1077217282192378 1.095171551640597 1.1766054665233883 1.1992995445963561 1.013222813724974 1.0766765639435483 1.0 13.580265474182832 -7.7734974280328295 24.994840218820915 1.033712231935819 1.1425055214084532 0.3473052734300778 0.07318305072909372 274.3870880571953 568761.771568532 0.03800908073044685 0.018476923233883922 1.6846224033702703e-08 7.7734974280328295 0.10879328947263422 TPMYGS(ph)QTPMYGSGSR ddPTM_PC-9_AZD4547_30min_R2 1 TPMYGSQTPMYGSGSR 16 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 T(0.014)PMY(0.177)GS(0.382)QT(0.354)PMY(0.071)GS(0.001)GSR 88.155 0.0024311 9236800.0 11259.0 10005.0 19364.0 22806.0 17771.0 18611.0 13681.0 27584.0 20505.0 20289.0 True False 14839.127798251733 13238.920591561406 19107.220707787168 17548.429049187595 15303.803399788714 17447.251227917714 14898.582496391196 23321.52661726166 21588.85243821283 19578.688285490978 0.7579224706921989 0.6761903759084957 0.9759193480774094 0.8963025915373538 0.7816562160157472 0.8911348387341765 0.7609591755660143 1.1911690036223908 1.1026710330850666 1.0 14.25699649140584 -7.759335696775337 24.999998763488133 1.110190043441526 0.8246714628413505 0.6591006313913046 0.09142866736618087 32.85378908604115 390447.64130551676 0.04655994554902297 0.025176983552612837 1.740461028468387e-08 7.759335696775337 -0.28551858060017543 TPMYGSQT(ph)PLQDGSR ddPTM_PC-9_AZD4547_30min_R2 2 TPMYGSQTPLQDGSR 15 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 TPMYGS(0.04)QT(0.958)PLQDGS(0.002)R;T(0.003)PMY(0.029)GS(0.386)QT(0.583)PLQDGSR 120.32 0.00031862 9226700.0 12532.6 11896.0 15755.2 27245.2 18627.3 25008.9 14420.8 22760.8 15839.2 18372.6 True False 16517.706105726043 15741.149361040942 15546.275753735199 20964.240074143898 16041.220925602624 23445.089529518616 15704.22326320868 19243.641351151724 16676.427775632306 17729.38086618422 0.9316572434421982 0.8878566871483092 0.8768651241164929 1.182457539401707 0.9047817883025191 1.3223862528801635 0.8857739241849001 1.0854096652554686 0.9406097089064039 1.0 14.113854535815282 -5.727548668629414 24.983303999127948 1.0484420919415878 0.8976992218296668 0.22419191421365026 0.1253514885160932 262.0138529154016 193147.51883473704 0.03181850047378338 0.05510738973327967 1.8726272177976994e-06 5.727548668629414 -0.150742870111921 TPMYGSQT(ph)PLQDGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TPMYGSQTPLQDGSR 15 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 TPMYGS(0.377)QT(0.621)PLQDGS(0.001)R;T(0.068)PMYGS(0.341)QT(0.591)PLQDGSR;T(0.003)PMY(0.104)GS(0.224)QT(0.669)PLQDGSR 132.4 2.5933e-05 26052400.0 38386.0 38636.0 45690.0 43316.0 60508.0 45516.0 48933.0 43223.0 39260.0 34972.3 True False 44883.991641941284 42471.52674357137 46779.4228802899 40889.14495236675 48651.8917603124 43129.06083366141 44297.71199575904 42088.44204855407 39834.10322737711 41312.50114942553 1.0864505995315517 1.0280550816798453 1.132330930802053 0.9897523464985206 1.1776554410090208 1.043971186292146 1.0722592620460363 1.0187822300160911 0.9642142721714884 1.0 15.334290786309458 -7.896464457677522 2.651020066090632 0.982290946564157 1.0763190209252986 0.370040939116252 0.05011112380302901 0.2896058288642171 3.9715356373026385 0.033024195588787914 0.012975676149961902 1.2692160118457632e-08 7.896464457677522 0.09402807436114158 TPMYGSQT(ph)PLQDGSR ddPTM_PC-9_Lapatinib_30min_R1 5 TPMYGSQTPLQDGSR 15 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 TPMYGSQT(0.983)PLQDGS(0.017)R;TPMYGS(0.02)QT(0.98)PLQDGSR;TPMYGS(0.021)QT(0.979)PLQDGSR;TPMYGS(0.047)QT(0.724)PLQDGS(0.228)R;T(0.001)PMY(0.001)GS(0.387)QT(0.61)PLQDGSR 163.34 3.9677e-05 26293200.0 56083.799999999996 45923.4 50926.5 41058.8 47753.6 47009.3 40855.899999999994 37994.5 48488.9 35641.4 True False 55284.034727490725 45817.0671888253 46739.5197519749 44078.401120141636 44944.82713518987 44998.8218230306 42971.21859254596 39759.86317574154 43027.56947124662 41801.96850081973 1.3225222808922652 1.0960504692004358 1.1181176731200673 1.0544575459234 1.0751844649207971 1.076476143034943 1.027971172977256 0.9511481062180567 1.0293192166393519 1.0 15.351283261556599 -1.5228787452803376 0.5570531613494563 1.0181215186664265 13.947743085544252 0.826184205494723 0.03938801641165632 58.392530713804184 0.5228845326447831 0.02004664825147149 905.7799820096576 0.029999999999999995 1.5228787452803376 12.929621566877826 TPMYGSQT(ph)PMYGSGSR ddPTM_PC-9_AZD4547_30min_R2 1 TPMYGSQTPMYGSGSR 16 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 TPMY(0.006)GS(0.018)QT(0.596)PMY(0.371)GS(0.008)GSR 86.411 0.003988599999999999 9445500.0 8381.3 10062.0 15068.0 18378.0 14722.0 15984.0 11733.0 21486.0 14362.0 16935.0 True False 11046.37905813014 13314.344726865662 14868.188474743692 14141.236037269562 12678.104420217736 14984.51795320168 12777.214270167231 18165.832399161973 15121.145999395882 16342.11080461282 0.6759456712906465 0.8147261321412334 0.9098083260178919 0.8653249391307501 0.7757935661921433 0.9169267135902702 0.7818582570472268 1.1115964526463973 0.9252872031150161 1.0 13.996306718643284 -1.9941386123732285 0.1582276338217733 1.0454212516507864 1.2842296647240975e-17 0.45591549397940734 0.08693082249804736 54.02353687441296 0.6338389964753534 0.28073028403043454 12.751515237938515 0.010135878305369111 1.9941386123732285 -1.0454212516507864 TPMYGSQT(ph)PMYGSGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPMYGSQTPMYGSGSR 16 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 T(0.004)PMY(0.014)GS(0.156)QT(0.824)PMY(0.002)GSGSR 80.488 0.007125399999999999 6903600.0 11978.0 11367.0 14821.0 11317.0 18333.0 13234.0 13490.0 10903.0 10554.0 11785.0 True False 14005.638823716268 12495.440638114093 15174.38884895551 10682.945180209037 14740.780254541667 12539.985742874484 12212.129540857695 10616.80780268341 10708.332283793636 13921.527209991327 1.0060418381156182 0.8975624907837878 1.0899945544814234 0.7673687677413729 1.058847928980261 0.9007622190958097 0.877211914802938 0.7626180405741579 0.7691923538466658 1.0 13.765029864976327 -7.252255425307924 2.6223218029133135 0.8264638290102454 0.9568952422521397 0.186149048265149 0.10481772857526173 0.4120714237603732 5.617739211748744 0.045586758037068284 0.03075277614558528 5.5942848328845366e-08 7.252255425307924 0.13043141324189433 TPMYGSQT(ph)PMYGSGSR ddPTM_PC-9_Lapatinib_30min_R1 1 TPMYGSQTPMYGSGSR 16 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 TPMY(0.001)GS(0.021)QT(0.834)PMY(0.03)GS(0.101)GS(0.013)R 83.964 0.0045173999999999995 5091100.0 15701.0 11371.0 14038.0 11232.0 14223.0 12535.0 11238.0 9734.2 12857.0 8390.3 True False 15477.100860789245 11344.671148132153 12883.849828247052 12058.03874885361 13386.431103493884 11998.907270512176 11819.848652043698 10186.486468444211 11408.909269787882 9840.552175627994 1.5727878461049412 1.1528490419703679 1.3092608624296882 1.2253416814066231 1.3603333293275894 1.2193327220224248 1.2011367290260204 1.0351539513883163 1.1593769400506024 1.0 13.264523555377993 -1.5228787452842836 0.10436577004784539 0.8646185001686267 2.463934385705468 0.5673019033502151 0.102568168862626 92.41043832547055 0.681689771140001 1.122459041467135 21.199800689293586 0.02999999999972742 1.5228787452842836 1.5993158855368415 TPMYGSQTPLQDGS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 TPMYGSQTPLQDGSR 15 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 TPMYGS(0.016)QT(0.074)PLQDGS(0.91)R 120.59 0.0013085999999999998 0.0 3000.2 4138.6 3911.0 6883.1 5475.2 5133.4 4472.8 6136.8 4429.8 3518.2 True False 3954.201191963305 5476.321515265972 3859.137584597998 5296.307637834915 4715.062988831423 4812.407686496843 4870.870535038265 5188.498569634977 4663.950184384059 3395.0288888567366 1.164703253318963 1.613041212474072 1.136702429032216 1.5600184302462379 1.388813804886121 1.417486520451201 1.4347066533146682 1.5282634520916212 1.373758615042191 1.0 11.729208135312662 -8.57036122551295 20.850470108187476 0.9999999984584997 1.4119999477069427 0.40562591279279037 0.14624361072926348 3372.3526518675503 1480863.1863130184 0.12827375372395397 0.03312014078790634 2.6892970439353873e-09 8.57036122551295 0.41199994924844296 TPMYGSQTPMY(ph)GSGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPMYGSQTPMYGSGSR 16 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 T(0.004)PMY(0.008)GS(0.011)QT(0.127)PMY(0.823)GS(0.026)GS(0.002)R 54.005 0.028418000000000002 8094800.0 11184.0 13992.0 19290.0 12509.0 27445.0 18397.0 17870.0 15936.0 13459.0 15173.0 True False 13077.2303059311 15381.03329009346 19749.946757732374 11808.161284725178 22067.34926558097 17432.22893393243 16177.224232403774 15517.696885587711 13655.812413073578 17923.744790598077 0.7296036882198176 0.8581372625971332 1.101887300252804 0.6587999005051202 1.2311796180648826 0.972577390360776 0.9025582779380767 0.8657619859510352 0.7618838904823478 1.0 14.12958446931141 -1.6106223887301447 17.759575369730026 0.9121686021884946 0.004535663188137029 0.0 0.1656506106762734 0.0 0.0 0.03684910407998057 0.0 0.02451193584461712 1.6106223887301447 -0.9076329390003576 TPMYGSQTPMY(ph)GSGSR ddPTM_PC-9_Lapatinib_30min_R1 1 TPMYGSQTPMYGSGSR 16 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 T(0.044)PMY(0.109)GS(0.138)QT(0.138)PMY(0.567)GS(0.003)GSR 49.632 0.039277 5359000.0 12537.0 11217.0 15601.0 9298.3 14632.0 11466.0 11217.0 9632.4 14487.0 9166.7 True False 12358.220080995778 11191.027725670432 14318.346001601536 9982.12800021951 13771.374527618815 10975.625908551467 11797.761374797486 10079.956468805041 12855.321505126947 10751.151881140033 1.1494786993638242 1.04091429917403 1.3317964586398574 0.9284705593016908 1.2809208427030911 1.0208790676471804 1.097348591595422 0.9375699069499315 1.1957157379274035 1.0 13.392203618357831 TPNTEQQTPLFQVIS(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 1 TPNTEQQTPLFQVISPQR 18 0 Q8IZD4;Q8IZD4-2 Q8IZD4 DCP1B mRNA-decapping enzyme 1B 1 TPNTEQQT(0.001)PLFQVIS(0.999)PQR 92.096 0.008736399999999998 0.0 8548.0 8019.9 8991.5 6417.8 8183.5 6076.0 10816.0 6523.7 6899.6 7494.6 True False 8426.103952488786 8001.330414291184 8252.253578193717 6889.786421153198 7702.162619380036 5816.14364384779 11375.999556905543 6826.814917937736 6122.494391991014 8790.031624073228 0.9585976834727471 0.9102732227240194 0.9388195550506666 0.7838181608225577 0.8762383286865716 0.6616749395894252 1.2941932456477327 0.7766541930567306 0.6965270039783885 1.0 13.101652640453013 TPPGALLGAPPPLVPAPRPS(ph)SPPR ddPTM_PC-9_AZD4547_30min_R2 2 TPPGALLGAPPPLVPAPRPSSPPR 24 1 J3KNZ9;Q9HAH7 J3KNZ9 FBRS Probable fibrosin-1 1 TPPGALLGAPPPLVPAPRPS(0.5)S(0.5)PPR;TPPGALLGAPPPLVPAPRPS(0.5)S(0.5)PPR 111.55 1.9393000000000002e-07 37282000.0 25850.0 30672.0 40476.0 32279.0 42649.0 41838.0 34360.0 39923.0 30333.0 35356.0 True False 34069.76228659802 40586.12417634901 39939.2617934514 24837.57525557864 36727.922525327165 39221.86324612439 37417.973435860054 33753.81768927412 31936.34045395316 34118.19720152886 0.9985803788328924 1.1895741130932416 1.1706146593132913 0.7279861567382478 1.0764907157427814 1.1495877995677577 1.0967160197486439 0.9893200830600036 0.9360500575488222 1.0 15.058253796512568 -1.5228787493372296 0.16949352262167303 0.9852164246451203 1.406388147542288 0.03254263874238539 0.1280974508279748 258.49798115355543 2.7919686352643445 0.3567828198078791 27.578202453541273 0.02999999971975983 1.5228787493372296 0.42117172289716764 TPPGALLGAPPPLVPAPRPS(ph)SPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPPGALLGAPPPLVPAPRPSSPPR 24 1 J3KNZ9;Q9HAH7 J3KNZ9 FBRS Probable fibrosin-1 1 TPPGALLGAPPPLVPAPRPS(0.5)S(0.5)PPR 123.43 1.6100999999999998e-09 15665000.0 16748.0 19560.0 20131.0 22206.0 27737.0 15470.0 21939.0 13818.0 17622.0 15055.0 True False 19583.105611921874 21501.78753246342 20610.999387242635 20961.86981282335 22302.133961720498 14658.725966621436 19860.77909539487 13455.2921413812 17879.68841245134 17784.35232468558 1.1011424680751254 1.2090284279072592 1.15894011831027 1.1786692835435573 1.2540312716794306 0.8242485134684597 1.116755827415042 0.7565803857082034 1.0053606724622426 1.0 14.118320814450838 -6.755877323072594 24.99997844778101 0.9363857700757534 1.1806707109387016 0.5914274557186068 0.09961395493097536 90.44952254614414 406546.74671145855 0.031164338363705794 0.030329968518870345 1.7543759975744623e-07 6.755877323072594 0.24428494086294816 TPPGALLGAPPPLVPAPRPS(ph)SPPR ddPTM_PC-9_Lapatinib_30min_R1 2 TPPGALLGAPPPLVPAPRPSSPPR 24 1 J3KNZ9;Q9HAH7 J3KNZ9 FBRS Probable fibrosin-1 1 TPPGALLGAPPPLVPAPRPS(0.5)S(0.5)PPR;TPPGALLGAPPPLVPAPRPS(0.5)S(0.5)PPR 82.6 2.9981e-05 27491000.0 25638.0 26207.0 21140.3 17461.8 18359.1 17915.800000000003 16763.0 12756.5 21206.3 11853.5 True False 25272.397418566627 26146.319301653286 19402.226137917874 18745.999022857188 17279.253833379364 17149.582997769627 17630.90611801106 13349.213559892805 18817.823181761138 13902.361681204071 1.8178492257710999 1.8807106232175639 1.395606486353293 1.348403922493377 1.2429006113933028 1.2335733590470304 1.2681950392535077 0.9602119313253719 1.3535702503843465 1.0 13.7630423629547 -5.380678215292983 1.0225126406741873 1.1687908909491638 1.9868346761728164 0.8090226991679319 0.12428169303818863 0.33812700149032 0.5264604330196249 0.0420475441600438 0.24521370006179743 4.162188881095755e-06 5.380678215292983 0.8180437852236526 TPPGALLGAPPPLVPAPRPS(ph)SPPRGPGPAR ddPTM_PC-9_AZD4547_30min_R2 1 TPPGALLGAPPPLVPAPRPSSPPRGPGPAR 30 2 J3KNZ9;Q9HAH7 J3KNZ9 FBRS Probable fibrosin-1 1 TPPGALLGAPPPLVPAPRPS(0.5)S(0.5)PPRGPGPAR 86.18 3.5125e-09 8618100.0 9630.2 7168.3 11751.0 25228.0 19108.0 13704.0 6471.8 8749.2 10515.0 17385.0 True False 12692.403279396372 9485.312791253338 11595.174062033 19412.074368714588 16455.18402808862 12847.086713630883 7047.777662462134 7397.2121766149085 11070.80143320204 16776.35644158216 0.7565649504165736 0.5653976669059607 0.6911616418266487 1.157109080050272 0.980855651546752 0.765785273957811 0.4201018073861016 0.44093079461998397 0.6599049961624422 1.0 14.034141798876755 -7.020053796529668 22.180368291631076 0.5849734510716 0.830678794770954 0.15282082512250794 0.2121873024706809 290.85348534639525 321695.16947864875 0.08458840054654283 0.06661905318819375 9.548742973778953e-08 7.020053796529668 0.24570534369935393 TPPGALLGAPPPLVPAPRPS(ph)SPPRGPGPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPPGALLGAPPPLVPAPRPSSPPRGPGPAR 30 2 J3KNZ9;Q9HAH7 J3KNZ9 FBRS Probable fibrosin-1 1 TPPGALLGAPPPLVPAPRPS(0.5)S(0.5)PPRGPGPAR 61.611999999999995 0.0002303 5642200.0 7130.6 4333.7 6499.8 10917.0 8615.4 9116.4 8941.2 9253.7 10866.0 6949.8 True False 8337.66974423036 4763.921095574472 6654.779882628772 10305.355883391547 6927.274216166381 8638.319935495001 8094.22480731778 9010.800180105609 11024.894693547629 8209.74372541347 1.015582218287873 0.5802764684149194 0.8105953249221084 1.255259144264279 0.8437869010116392 1.0522033603503194 0.9859290470008099 1.0975738685012115 1.3429036352766759 1.0 13.003121472335605 -5.964403708575282 0.6164572887779107 1.1234008316726338 0.751093951053429 0.26448477919685875 0.17822158522661233 1.519793102497599 1.06563642425012 0.11571255778890609 0.33616950310539023 1.085416180561833e-06 5.964403708575282 -0.3723068806192048 TPPGALLGAPPPLVPAPRPS(ph)SPPRGPGPAR ddPTM_PC-9_Lapatinib_30min_R1 1 TPPGALLGAPPPLVPAPRPSSPPRGPGPAR 30 2 J3KNZ9;Q9HAH7 J3KNZ9 FBRS Probable fibrosin-1 1 TPPGALLGAPPPLVPAPRPS(0.5)S(0.5)PPRGPGPAR 51.263999999999996 0.0029711 5966200.0 15729.0 12557.0 13806.0 12343.0 9530.2 10481.0 8489.5 9402.8 9181.4 9167.0 True False 15504.701575654672 12527.925037999783 12670.923972701157 13250.745395040969 8969.652373094097 10032.752062404325 8929.044770557479 9839.688414609027 8147.294047571791 10751.503735740296 1.4420960971360435 1.1652253811115074 1.1785257471083137 1.2324550798408467 0.8342695676398322 0.9331487305402045 0.8304926445661202 0.9151918332967508 0.7577818180435956 1.0 13.392250832887608 -6.256415770305392 23.917202750423556 0.8745743414933546 1.2427613327851266 0.7938275220199904 0.0938078398733095 101.1417272071823 481530.2229837836 0.027064800900723246 0.033816934051048 5.540949980483147e-07 6.256415770305392 0.368186991291772 TPPGPCCS(ph)PGVGWAQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPPGPCCSPGVGWAQR 16 0 H3BSW6;Q2VPK5-3;Q2VPK5-5;Q2VPK5 H3BSW6 CTU2 Cytoplasmic tRNA 2-thiolation protein 2 1 T(0.001)PPGPCCS(0.999)PGVGWAQR 90.82700000000001 0.0043146999999999994 4720600.0 3835.2 4413.8 6736.5 7045.1 6799.7 7463.7 7464.3 3578.3 6313.4 3839.7 True False 4484.423611347192 4851.972894212013 6897.123708318514 6650.385887522372 5467.347597054872 7072.290432907079 6757.227467147818 3484.373416522243 6405.721531220652 4535.807214951522 0.9886715635896179 1.0697043909225912 1.520594545020192 1.4661967699157272 1.2053747740937235 1.5592131891308054 1.4897519111645132 0.7681925733167395 1.4122561272236778 1.0 12.147143607494261 -7.7403512055991435 24.9992203464938 1.067667892405155 1.3353694036499006 0.21632056163496838 0.2336762424532704 364.9366249764221 432619.2855807571 0.11230908869086534 0.06475752150956576 1.81822989635505e-08 7.7403512055991435 0.2677015112447456 TPPPPT(ph)LSPAAITVGR ddPTM_PC-9_Lapatinib_30min_R1 1 TPPPPTLSPAAITVGR 16 0 Q8NDX5-2;Q8NDX5;Q8NDX5-7;E7EX82;H7C4H9 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 1 T(0.006)PPPPT(0.495)LS(0.495)PAAIT(0.004)VGR 71.697 0.04294 3825900.0 5679.3 5274.5 3592.7 3469.8 5592.0 4982.8 3923.0 3863.2 6732.0 4232.1 True False 5598.312140543937 5262.287219314311 3297.3220742230505 3724.9806669134823 5263.089554294999 4769.697259474122 4126.113744613581 4042.698375304972 5973.771268897259 4963.61284608122 1.12787042707487 1.0601727778726528 0.6642988034061302 0.7504575361582362 1.060334421217041 0.9609325721766969 0.8312722753691707 0.8144669015627778 1.2035127344014271 1.0 12.277174876596728 -8.25938248934616 24.99952662060812 1.101756367466705 0.9045628508563162 0.21497706622110413 0.1473756554539823 281.9544921272709 3426999.0704864953 0.11794577764593572 0.03954959318905216 5.503228057653667e-09 8.25938248934616 -0.19719351661038886 TPPPPTLS(ph)PAAITVGR ddPTM_PC-9_AZD4547_30min_R2 2 TPPPPTLSPAAITVGR 16 0 Q8NDX5-2;Q8NDX5;Q8NDX5-7;E7EX82;H7C4H9 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 1 T(0.002)PPPPT(0.196)LS(0.802)PAAITVGR;T(0.002)PPPPT(0.042)LS(0.943)PAAIT(0.013)VGR 140.68 2.1672e-05 11442100.0 0.0 1085.0 2252.9 7218.7 3963.7999999999997 0.0 3548.3 1945.2 2445.35 3920.5 True False 0.0 1435.7050316685795 2223.0250739812896 5554.540242803233 3413.4947901683913 0.0 3864.0918260320786 1644.6140362491788 2574.6062087190307 3783.244488307328 0.0 0.3794904178426312 0.5875975187043487 1.4681948946123768 0.9022665071523391 0.0 1.021369842201481 0.43470995367391657 0.680528635322467 1.0 11.885408296754145 -5.036413017048025 2.334736333773951 0.7552392108540864 1.2203862436995105e-06 0.30585083262065793 0.3691155708129482 0.48676367266424087 4.518493785587902 0.10299215083249363 0.6007488172256462 9.195746339631123e-06 5.036413017048025 -0.7552379904678427 TPPPPTLS(ph)PAAITVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPPPPTLSPAAITVGR 16 0 Q8NDX5-2;Q8NDX5;Q8NDX5-7;E7EX82;H7C4H9 Q8NDX5-2 PHC3 Polyhomeotic-like protein 3 1 T(0.106)PPPPT(0.324)LS(0.57)PAAIT(0.001)VGR 76.051 0.011798000000000001 4926900.0 1497.2 0.0 1895.7 1241.6 2074.4 4664.0 1924.6 991.21 1939.2 1250.4 True False 1750.6463889520785 0.0 1940.9006774822858 1172.037177321511 1667.9362112049976 4419.411629497249 1742.287955102647 965.1917877738076 1967.5571313940322 1477.087621839046 1.185201448491213 0.0 1.3140051062548137 0.7934784368866808 1.129206004128811 2.991976619501331 1.1795427226811457 0.6534424725407263 1.3320517363379756 1.0 10.5285396949511 -6.524450939920102 24.99964347457612 1.468066988587432 0.8196713986253994 0.1577737156554706 0.6600963624227363 98.26281838897683 1562445.5596765536 0.22632990748562012 0.22793477882553714 2.989159298293567e-07 6.524450939920102 -0.6483955899620326 TPPRDLPT(ph)IPGVTSPSSDEPPMEASQSHLR ddPTM_PC-9_AZD4547_30min_R2 2 TPPRDLPTIPGVTSPSSDEPPMEASQSHLR 30 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 T(0.302)PPRDLPT(0.656)IPGVT(0.006)S(0.007)PS(0.021)S(0.007)DEPPMEASQSHLR;T(0.303)PPRDLPT(0.411)IPGVT(0.016)S(0.019)PS(0.11)S(0.14)DEPPMEASQSHLR 76.967 1.2113e-06 9989700.0 2692.2 4272.0 18252.0 18360.8 15948.8 14130.9 11431.2 20935.1 7727.6 14280.6 True False 3548.2635987612857 5652.840456486794 18009.966554355065 14128.00123153222 13734.584416327172 13247.292589145247 12448.55465483129 17700.06133573935 8136.065159791924 13780.640540676337 0.25748176133670064 0.41020157515910066 1.3069034419115004 1.025206425625179 0.9966579112042564 0.961297303274343 0.9033364318651861 1.2844149938817468 0.5903981847416082 1.0 13.75035532734348 -5.142418138060067 5.656730057497902 1.0121115310545974 0.29820504065608705 0.6719995742811733 0.18940654435565588 0.11623700272429831 4.85290120324324 0.045688176123307785 0.12690013589247687 7.204135321288042e-06 5.142418138060067 -0.7139064903985104 TPPRDLPT(ph)IPGVTSPSSDEPPMEASQSHLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPPRDLPTIPGVTSPSSDEPPMEASQSHLR 30 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 T(0.425)PPRDLPT(0.567)IPGVT(0.003)S(0.003)PS(0.001)S(0.001)DEPPMEASQSHLR 57.073 0.0013709000000000002 52839000.0 7796.4 2315.5 11872.0 9577.2 10896.0 10062.0 11160.0 7870.3 7841.2 5835.6 True False 9116.176534080942 2545.3675373936107 12155.073504810716 9040.62053370133 8761.007017590468 9534.331006861345 10102.844008596881 7663.7129642721475 7955.862715907014 6893.548085415815 1.322421548544411 0.3692391067494926 1.7632536038337547 1.3114611549352826 1.2708995293911856 1.3830803656875108 1.465550669033664 1.1117225656967151 1.1541027374188717 1.0 12.751031008911289 -5.263795389900025 24.99839839539295 1.3186759223506666 0.8458303600569201 0.285388727072282 0.2917963471575179 224.86232153779588 2385926.5932968697 0.07136012304459312 0.16078641527899967 5.447592459965881e-06 5.263795389900025 -0.4728455622937464 TPPRDLPT(ph)IPGVTSPSSDEPPMEASQSHLR ddPTM_PC-9_Lapatinib_30min_R1 2 TPPRDLPTIPGVTSPSSDEPPMEASQSHLR 30 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 T(0.135)PPRDLPT(0.811)IPGVT(0.043)S(0.011)PS(0.001)SDEPPMEASQSHLR;T(0.185)PPRDLPT(0.814)IPGVT(0.001)SPSSDEPPMEASQSHLR 101.71 5.6052e-13 28643000.0 12163.0 14078.8 20031.0 9752.9 14836.3 19774.800000000003 12105.8 16171.8 16776.4 12726.0 True False 11989.553389578976 14046.2014035989 18384.12850189606 10470.160800720658 13963.658003288081 18929.077901310277 12732.579089865672 16923.20086605844 14886.865168676159 14925.672143670896 0.8032839844109161 0.9410766408637129 1.2317119339708726 0.7014867203257201 0.9355463438347902 1.268222812286346 0.8530657090216747 1.1338317432648806 0.9973999847630853 1.0 13.865508280989705 -6.569708019447236 24.999972457818174 1.0526793389115636 0.9276547522889464 0.13655032401157918 0.16061513198238858 265.72684944142594 141857.42306075955 0.05225589854921301 0.05225591527409319 2.693344958298931e-07 6.569708019447236 -0.12502458662261717 TPPSEEDS(ph)AEAER ddPTM_PC-9_Lapatinib_30min_R1 1 TPPSEEDSAEAER 13 0 O43765;K7EMD6 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 TPPSEEDS(1)AEAER 54.343 0.046319 294110.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TPPSEEDSAEAER ddPTM_PC-9_Lapatinib_30min_R1 1 TPPSEEDSAEAER 13 0 O43765;K7EMD6 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 0 112.83 0.001888 0.0 1086.4 1492.2 4386.3 1476.1 1403.1 1587.4 1747.5 641.56 4512.2 2001.1 False True 1070.9077367786397 1488.7449025804951 4025.675345607643 1584.65731812525 1320.5724166007353 1519.5106024101349 1837.976999416832 671.3692197299284 4003.9885204275406 2346.9874687018573 0.4562903513800905 0.6343216239684207 1.7152521687021556 0.6751878053280532 0.5626670079031812 0.6474302154031489 0.7831217779928905 0.28605573258610945 1.7060118870776022 1.0 11.196594423544921 -8.267438343896517 24.99895588948505 1.3530059034373252 0.7432986878505595 0.29179986524467705 0.3931010935860952 711.028267297385 2962959.300338282 0.35098718906866394 0.10002017108009109 5.40208801913585e-09 8.267438343896517 -0.6097072155867657 TPPSTT(ph)VGSHSPPETPVLTR ddPTM_PC-9_AZD4547_30min_R2 1 TPPSTTVGSHSPPETPVLTR 20 0 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;Q9ULU4-4;Q9ULU4-18;Q9ULU4-15;Q9ULU4-2 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 TPPS(0.01)T(0.006)T(0.847)VGS(0.096)HS(0.042)PPETPVLTR 203.17 1.4251e-20 8375500.0 2573.2 3410.0 13519.0 23141.0 16041.0 13559.0 7506.8 12202.0 9850.6 12130.0 True False 3391.4240741150475 4512.215813815534 13339.729226842313 17806.19997488601 13813.98403781502 12711.153586552913 8174.89065740146 10316.46127406564 10371.282605601527 11705.332392084654 0.28973325664877203 0.3854837831744762 1.1396284001181263 1.5212041297457617 1.1801445337132221 1.0859284607029538 0.6983903048263252 0.8813471440624623 0.8860305934255028 1.0 13.514878282269638 -5.239488760897974 8.003453119525533 1.055285064259823 0.33414077396889946 0.6507772023825567 0.20845135711297233 0.15816023880422891 48.204913305320524 0.06166697611952203 0.15737387128107969 5.7611772771115225e-06 5.239488760897974 -0.7211442902909235 TPPSTTVGS(ph)HSPPETPVLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPPSTTVGSHSPPETPVLTR 20 0 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;Q9ULU4-4;Q9ULU4-18;Q9ULU4-15;Q9ULU4-2 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 T(0.006)PPS(0.038)T(0.038)T(0.007)VGS(0.65)HS(0.234)PPET(0.025)PVLT(0.002)R 47.54600000000001 0.038907 3783000.0 6767.8 5530.0 7314.2 7147.7 9073.9 9447.4 9806.4 6628.1 7787.0 5096.8 True False 7913.454869856983 6078.981853503203 7488.598267257965 6747.237542156059 7295.934432536171 8951.961712802802 8877.46679981222 6454.119398052454 7900.870143443347 6020.8094937534015 1.3143506497036992 1.0096618834743327 1.2437859518769687 1.120652887150196 1.211786295531475 1.486836898275967 1.474463991764331 1.0719687119728023 1.3122604446529178 1.0 12.555741754057637 -6.532848951999899 24.908146876219572 1.2934247755266826 1.1657025424933096 0.06457672910462586 0.16132282968124145 444.47973306165215 1110415.7058512184 0.05266224340455801 0.052719311421130316 2.9319127897697015e-07 6.532848951999899 -0.12772223303337293 TPPSTTVGSHS(ph)PPETPVLTR ddPTM_PC-9_AZD4547_30min_R2 4 TPPSTTVGSHSPPETPVLTR 20 0 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;Q9ULU4-4;Q9ULU4-18;Q9ULU4-15;Q9ULU4-2 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 TPPSTTVGS(0.003)HS(0.995)PPET(0.001)PVLT(0.001)R;TPPSTTVGSHS(0.999)PPETPVLTR;TPPSTTVGS(0.036)HS(0.963)PPETPVLTR;T(0.002)PPS(0.008)T(0.008)T(0.014)VGS(0.046)HS(0.922)PPETPVLTR 108.96 5.1939e-05 210269000.0 45315.2 36220.1 85508.0 146887.0 119063.0 104126.0 78300.0 122022.0 84892.0 89428.0 True False 59724.49098528611 47927.5390023402 84374.10805006538 113024.47153152768 102533.15762697911 97614.98475945205 85268.54831280092 103166.30368661202 89379.21780954718 86297.15293976458 0.6920795061104021 0.5553779860593272 0.9777160100398504 1.3097126345572347 1.1881406759565667 1.1311495389377135 0.9880806655616828 1.1954774887952806 1.0357145602698374 1.0 16.397025343270748 -5.401268477762321 4.115604811001175 1.1281608330533879 0.6273589899980689 0.7955072852581103 0.09913678833718367 0.09054321498833609 2.5562178164129943 0.026548285370943215 0.05874453367542332 3.9694608435648255e-06 5.401268477762321 -0.5008018430553189 TPPSTTVGSHS(ph)PPETPVLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TPPSTTVGSHSPPETPVLTR 20 0 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;Q9ULU4-4;Q9ULU4-18;Q9ULU4-15;Q9ULU4-2 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 TPPSTTVGSHS(0.996)PPET(0.004)PVLTR;TPPSTTVGS(0.007)HS(0.993)PPETPVLTR;TPPSTTVGSHS(0.998)PPET(0.001)PVLTR;TPPSTTVGS(0.003)HS(0.995)PPET(0.002)PVLTR 129.74 7.7037e-06 167542000.0 39645.7 48659.3 71292.7 79323.0 104736.0 94615.4 80466.0 80397.0 80106.0 54454.2 True False 46356.93397173217 53489.87372588942 72992.5883470702 74878.7894786359 84213.73265366688 89653.60186310751 72843.67795660908 78286.66393766268 81277.39870433694 64326.31540078995 0.7206527170552488 0.8315395245727465 1.134723602498983 1.1640459897648103 1.3091645639730316 1.3937313415903585 1.1324086806892493 1.2170239108192615 1.2635170878035216 1.0 15.973121433300879 -5.230660739502346 1.8004435248001545 1.2310293396431082 0.6973797780941562 0.7489351046702102 0.1002141564264503 0.2015530960324092 1.1159078605478958 0.02838921399663737 0.1335433436186345 5.879484645092144e-06 5.230660739502346 -0.533649561548952 TPPSTTVGSHS(ph)PPETPVLTR ddPTM_PC-9_Lapatinib_30min_R1 2 TPPSTTVGSHSPPETPVLTR 20 0 Q9ULU4-19;Q9ULU4-16;H7C4X9;A0A087WVZ6;Q9ULU4-22;Q9ULU4-7;Q9ULU4-11;Q9ULU4-10;Q9ULU4-13;Q9ULU4;Q9ULU4-20;Q9ULU4-5;Q9ULU4-9;Q9ULU4-14;Q9ULU4-12;Q9ULU4-21;Q9ULU4-23;Q9ULU4-6;Q9ULU4-3;Q9ULU4-4;Q9ULU4-18;Q9ULU4-15;Q9ULU4-2 Q9ULU4-19 ZMYND8 Protein kinase C-binding protein 1 1 TPPSTTVGS(0.003)HS(0.997)PPETPVLTR;T(0.001)PPS(0.002)T(0.002)T(0.005)VGS(0.051)HS(0.939)PPET(0.001)PVLTR 129.26 1.7349e-05 154952000.0 31517.0 22820.7 34289.0 25538.0 29666.0 31215.0 20442.5 22014.1 34372.0 24780.0 True False 31067.561800490057 22767.860071249623 31469.89077936768 27416.149712270613 27921.10420560005 29880.007215718997 21500.91262407931 23036.955452423186 30500.663406793887 29063.189982725504 1.0689659950939971 0.7833916402425997 1.0828092442045303 0.9433289920537334 0.9607033578280884 1.0281048719524246 0.7397987845401334 0.7926506163334385 1.0494602768974357 1.0 14.826905441765957 -7.21416916034855 24.999300919859124 0.8781976678108757 0.9714611506588013 0.10113985141699311 0.11490460327690884 833.1618849083582 440625.7288355428 0.042617338441033395 0.03301112478463205 6.107041056005392e-08 7.21416916034855 0.09326348284792563 TPPT(ph)PPSSIVAK ddPTM_PC-9_Lapatinib_30min_R1 1 TPPTPPSSIVAK 12 0 Q96QT6;Q96QT6-4 Q96QT6 PHF12 PHD finger protein 12 1 T(0.189)PPT(0.808)PPS(0.001)S(0.001)IVAK 96.756 0.010231 14425000.0 82598.0 75429.0 82024.0 72017.0 89821.0 76911.0 81617.0 81425.0 85112.0 68706.0 True False 81420.13737338189 75254.34878484384 75280.30334179629 77313.37042166927 84537.90537488039 73621.69581829778 85842.72890495203 85208.30275657665 75525.79029090662 80581.74055500975 1.0104043026695335 0.9338883507172555 0.9342104405204006 0.9594403135148304 1.049095052956444 0.9136275204683543 1.0652875988245851 1.0574145230631813 0.9372568744571651 1.0 16.298165347395866 -6.094468898631381 11.066250132885665 1.0051963573159788 0.9552604280427585 0.15540017374405946 0.05023267366317307 1.053571890153786 118.85375696378213 0.01465941813984527 0.018935945308774176 8.04509360258708e-07 6.094468898631381 -0.049935929273220325 TPPVAVTS(ph)PITHTAQSALK ddPTM_PC-9_AZD4547_30min_R2 2 TPPVAVTSPITHTAQSALK 19 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 T(0.002)PPVAVT(0.041)S(0.957)PIT(0.001)HTAQSALK;TPPVAVT(0.163)S(0.836)PIT(0.001)HTAQSALK 97.97399999999999 0.00032706 35565000.0 68484.0 76872.0 106182.0 194413.0 192752.0 184329.0 126496.0 198093.0 129969.0 157620.0 True False 90260.48744430857 101719.37068610794 104773.95730191376 149594.08650090802 165991.71194170704 172802.87849072274 137753.8989447775 167482.27857429013 136838.89600302762 152101.77177579392 0.593421670178552 0.668758617986697 0.68884113629101 0.9835131093766457 1.0913200418624158 1.136100365388533 0.9056692590526431 1.1011198398212474 0.8996535306947996 1.0 17.214677433003914 -5.7550149550202185 3.5516510196171143 1.0286979869899042 0.6402235392532448 0.8348664946924832 0.07508276833314323 0.08259997755838837 2.2061721224173256 0.02107565798237743 0.03607497866511747 1.757863080538069e-06 5.7550149550202185 -0.3884744477366594 TPPVAVTS(ph)PITHTAQSALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPPVAVTSPITHTAQSALK 19 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 TPPVAVT(0.057)S(0.943)PITHTAQSALK;T(0.075)PPVAVT(0.122)S(0.779)PIT(0.023)HT(0.001)AQSALK 95.624 0.00039712 28453000.0 54882.0 68471.0 81018.0 84192.0 125977.0 99703.0 128359.0 100625.0 107280.0 90126.0 True False 64172.43863109 75268.34837092552 82949.77638247608 79474.99519414674 101292.71118346133 94474.39916289966 116199.90628131595 97983.70037100042 108848.76704617962 106465.13036297665 0.6027554600487863 0.7069765294449887 0.7791262369159878 0.746488497437507 0.9514167769120205 0.8873740993018426 1.0914362842101453 0.9203360765815053 1.0223888955480196 1.0 16.700021468364866 -5.887035325139387 0.6638254689133233 1.0113083501118214 0.5929401582030923 0.8462411709422993 0.058177218786923654 0.3901348794536707 0.31093504769977304 0.032526478607228064 0.10221428897940903 1.2970737638294454e-06 5.887035325139387 -0.4183681919087291 TPPVAVTS(ph)PITHTAQSALK ddPTM_PC-9_Lapatinib_30min_R1 2 TPPVAVTSPITHTAQSALK 19 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 T(0.001)PPVAVT(0.236)S(0.763)PITHTAQSALK;T(0.001)PPVAVT(0.177)S(0.822)PIT(0.001)HTAQSALK 127.74 1.8873e-05 22258000.0 69863.0 69403.0 102141.0 67730.0 162681.0 141291.0 155983.0 130917.0 150741.0 127557.0 True False 68866.74080869493 69242.30161760765 93743.36125566215 72711.09014065674 153112.42342315178 135248.3132954077 164059.03650931935 136999.8817560054 133762.96120689853 149605.05749098127 0.4603236144797208 0.46283396282763917 0.6266055628588181 0.48602026803164744 1.023444166868369 0.9040357028274992 1.0966142405928316 0.9157436523445355 0.8941072143564548 1.0 17.19079942167992 -6.259574624520902 24.999944932524564 0.9709114350683948 0.5140563916462918 0.9086659422073412 0.07196254132921663 47.017807855195045 630346.5268970047 0.021820146703862803 0.026744453150869592 5.500793926274659e-07 6.259574624520902 -0.45685504342210304 TPQASTYSYET(ph)SDLCYTAEKKSPSEAR ddPTM_PC-9_AZD4547_30min_R2 1 TPQASTYSYETSDLCYTAEKKSPSEAR 27 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TPQAST(0.001)Y(0.003)S(0.012)Y(0.018)ET(0.248)S(0.248)DLCY(0.211)T(0.106)AEKKS(0.106)PS(0.046)EAR 53.551 0.0031925 121850000.0 98900.0 51589.0 106830.0 162600.0 151620.0 125500.0 89370.0 108450.0 85894.0 140940.0 True False 130348.14275220656 68264.13537212013 105413.3643985179 125115.08214495773 130570.1801517059 117652.46516058646 97323.75686736932 91691.54443307819 90434.18148392346 136005.73349879723 0.9584018217390762 0.5019210118279597 0.7750655923593848 0.9199250570275715 0.9600343808510147 0.865055186527316 0.7155856916004942 0.6741741107104802 0.6649291846561984 1.0 17.05330794588248 -10.64369430239525 15.310526112103249 0.9999890917053383 0.7799128571412508 0.1787252356967074 0.14035582637495914 0.0 0.0 0.14312103079107566 0.0347119486587578 2.271463160285415e-11 10.64369430239525 -0.22007623456408754 TPQASTYSYETSDLCYT(ph)AEKKSPSEAR ddPTM_PC-9_AZD4547_30min_R2 1 TPQASTYSYETSDLCYTAEKKSPSEAR 27 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TPQASTYS(0.001)Y(0.02)ET(0.018)S(0.018)DLCY(0.275)T(0.304)AEKKS(0.304)PS(0.058)EAR 62.677 0.00048288 12779000.0 14845.0 12036.0 20551.0 46184.0 37604.0 21321.0 18786.0 18095.0 20370.0 28158.0 True False 19565.401204818092 15926.401623191729 20278.480312215146 35536.99233568708 32383.333692288285 19987.794499512827 20457.91760669578 15298.833531733962 21446.71661382079 27172.19699062816 0.7200522361723752 0.5861285941907765 0.7462952045875902 1.3078439092703467 1.1917819417935722 0.7355972910989395 0.7528989140536494 0.5630326298977817 0.7892890155778673 1.0 14.729843598011184 TPQASTYSYETSDLCYT(ph)AEKKSPSEAR ddPTM_PC-9_Lapatinib_30min_R1 1 TPQASTYSYETSDLCYTAEKKSPSEAR 27 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TPQASTYSY(0.002)ET(0.018)S(0.024)DLCY(0.197)T(0.319)AEKKS(0.319)PS(0.122)EAR 59.788999999999994 0.0010424000000000002 8261500.0 16022.0 11700.0 15519.0 13618.0 14740.0 12496.0 10675.0 7395.0 11973.0 7097.9 True False 15793.523341925056 11672.909368845863 14243.087725072375 14619.51314831628 13873.022179954993 11961.575209598745 11227.699266823853 7738.598696774764 10624.474658720565 8324.762557642753 1.8971740313993009 1.4021912682817916 1.710930206891746 1.7561477636253393 1.6664766212723419 1.436866832750338 1.348711052006641 0.929587918356921 1.2762495729042151 1.0 13.02319340828184 -7.257069209903868 1.5309351952676438 1.0747897645973896 1.677517373398044 0.7544446682939621 0.15065423675559736 0.19385761463023346 0.8869671726741681 0.08328981081520871 0.04999355894360074 5.532619334316545e-08 7.257069209903868 0.6027276088006543 TPQASTYSYETSDLCYTAEKKS(ph)PSEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPQASTYSYETSDLCYTAEKKSPSEAR 27 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TPQASTYSYET(0.001)S(0.01)DLCY(0.188)T(0.346)AEKKS(0.426)PS(0.028)EAR 81.38600000000001 4.6226999999999996e-05 18422000.0 16408.0 3093.5 11289.0 30404.0 26674.0 28484.0 22350.0 33818.0 22648.0 18775.0 True False 19185.550327227968 3400.6022357707343 11558.172573770915 28700.562451097943 21447.42118091115 26990.24889678378 20232.84620001255 32930.31333313284 22979.184154193514 22178.75887718179 0.8650416569056382 0.15332698527460803 0.5211370319581917 1.2940562909778506 0.9670253101032149 1.2169413557470163 0.9122623277549018 1.4847680844311173 1.0360897235703854 1.0 14.436891014127795 -5.74815123831417 20.40457833062036 1.1381008170893017 0.47718029274336193 0.6056477440270149 0.22753323053568938 15.209117010522858 23351.78495394789 0.05819448916555634 0.0995349034575397 1.7858655583603146e-06 5.74815123831417 -0.6609205243459397 TPQASTYSYETSDLCYTAEKKS(ph)PSEAR ddPTM_PC-9_Lapatinib_30min_R1 2 TPQASTYSYETSDLCYTAEKKSPSEAR 27 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TPQASTYS(0.001)Y(0.001)ET(0.003)S(0.003)DLCY(0.006)T(0.009)AEKKS(0.916)PS(0.06)EAR;TPQASTYSY(0.001)ET(0.008)S(0.008)DLCY(0.017)T(0.008)AEKKS(0.712)PS(0.245)EAR 69.528 0.00065787 53685000.0 103794.0 54927.0 95576.0 91425.0 65825.0 69302.0 48813.0 53621.0 84758.0 64260.0 True False 102313.87852651159 54799.8199062048 87718.1102140293 98148.69948485939 61953.302916929344 66338.11501085239 51340.29829615669 56112.4274130845 75211.66149869196 75367.25537893224 1.3575375408338388 0.72710382819013 1.1638756084853998 1.302272439023902 0.8220188277447534 0.8801981003197867 0.6812016443749666 0.7445199792796205 0.9979355241283766 1.0 16.201650235096768 -6.289527323951079 24.05835744997658 0.8341770376239027 1.1102391245949186 0.35809665198748675 0.18322733752545603 515.7035214169827 441717.27439076354 0.056465202077255056 0.06404145297461536 5.134198743044828e-07 6.289527323951079 0.27606208697101586 TPQASTYSYETSDLCYTAEKKSPS(ph)EAR ddPTM_PC-9_AZD4547_30min_R2 1 TPQASTYSYETSDLCYTAEKKSPSEAR 27 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TPQASTYS(0.003)Y(0.011)ET(0.095)S(0.08)DLCY(0.068)T(0.11)AEKKS(0.262)PS(0.369)EAR 58.802 0.00083539 14348000.0 24118.0 13155.0 21135.0 39312.0 34972.0 25612.0 26972.0 19854.0 28269.0 31334.0 True False 31787.02231443603 17407.096489954063 20854.736090636325 30249.225764345465 30116.74146066124 24010.47759117878 29372.455748312474 16786.020499532795 29763.241627692685 30237.006197327315 1.051262221762078 0.5756884916567135 0.68970902590481 1.0004041262199836 0.9960225977439292 0.7940758894741734 0.9714075380554289 0.5551482309454476 0.9843316310304389 1.0 14.884027683192956 TPQEAIMDGTEIAVS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 TPQEAIMDGTEIAVSPR 17 0 Q06587 Q06587 RING1 E3 ubiquitin-protein ligase RING1 1 TPQEAIMDGT(0.005)EIAVS(0.995)PR 91.889 0.001884 3746500.0 5941.6 6298.8 10202.0 12049.0 7309.7 9109.1 7163.6 13434.0 7138.3 6202.2 True False 7830.9052070425805 8334.763920252573 10066.714814131616 9271.289205194307 6294.874329606413 8539.50653700635 7801.146522267958 11358.083982609234 7515.615964871721 5985.062865802753 1.3084081792668443 1.3925942144861105 1.6819731120370458 1.549071315218472 1.0517641118815728 1.4268031478498062 1.3034360201697934 1.8977384594415316 1.2557288258096988 1.0 12.547150685666377 TPQEAIMDGTEIAVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 TPQEAIMDGTEIAVSPR 17 0 Q06587 Q06587 RING1 E3 ubiquitin-protein ligase RING1 1 TPQEAIMDGT(0.004)EIAVS(0.996)PR;TPQEAIMDGTEIAVS(1)PR;TPQEAIMDGTEIAVS(1)PR;TPQEAIMDGTEIAVS(1)PR 150.29 7.9356e-12 6213400.0 19908.600000000002 17049.0 21917.0 15619.099999999999 19508.6 16672.9 17493.800000000003 14508.3 15803.5 11073.5 True False 19624.699713209902 17009.52408798743 20115.06886206659 16767.780717790196 18361.14250338331 15959.838933428207 18399.543366179212 15182.408583153117 14023.543411767358 12987.539720488732 1.5110405924110935 1.309680236138469 1.5487974855109543 1.2910667515678798 1.413750633187081 1.2288577572741102 1.4167073797012282 1.168998048121603 1.079769048917268 1.0 13.664840540957242 -7.997667500651429 0.6924606153408477 0.9821464723850494 1.417917479379665 0.7035078316965087 0.09333207960798058 0.35440843873235 0.35470108365706277 0.08388843263080062 0.038389220650849536 1.0053852267137877e-08 7.997667500651429 0.4357710069946156 TPQMPPT(ph)TPSS(ph)SS(ph)FTKVTK ddPTM_PC-9_Lapatinib_30min_R1 1 TPQMPPTTPSSSSFTKVTK 19 1 Q6K0P9-4;Q6K0P9-3 Q6K0P9-4 3 T(0.291)PQMPPT(0.563)T(0.145)PS(0.203)S(0.426)S(0.425)S(0.592)FT(0.202)KVT(0.153)K 41.853 0.043627 26225000.0 11547.0 14953.0 40859.0 24578.0 31200.0 37609.0 22531.0 27494.0 47273.0 24355.0 True False 11382.337662539547 14918.377247209584 37499.73074030106 26385.548109804506 29364.877341560077 36000.550740860985 23697.54493497032 28771.47161178168 41948.61693324123 28564.729299002403 0.39847525048791776 0.5222656616504535 1.3127983937033392 0.9237107704964667 1.0280117495314622 1.2603147876538172 0.8296085948133922 1.007237677998457 1.4685459292872154 1.0 14.801947237465804 -5.168617549483342 5.72261005411692 1.0898547469237418 0.4361661527135576 0.6607021310608279 0.18463209150554555 0.13011497887866333 6.369503621334963 0.046162312755350335 0.12733114316787522 6.78238518400094e-06 5.168617549483342 -0.6536885942101842 TPQNVPAS(ph)PGGDR ddPTM_PC-9_AZD4547_30min_R2 1 TPQNVPASPGGDR 13 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 TPQNVPAS(1)PGGDR 86.777 0.007426899999999999 6238100.0 5341.4 7302.7 10428.0 19665.0 16761.0 11860.0 9787.8 12871.0 11100.0 11039.0 True False 7039.854091978129 9663.154962918088 10289.717906465841 15131.538071221348 14434.02446591969 11118.392325135883 10658.895238518942 10882.082696156269 11686.72333890087 10652.527970010096 0.6608622959542867 0.9071231720885995 0.965941411788294 1.420464523897139 1.3549858312088534 1.0437327511776855 1.0005977237071586 1.0215493192594691 1.0970845016133568 1.0 13.37890821910988 -5.059117852533868 1.9313969517127052 1.1320032372627247 0.6532302812695165 0.49878172991183234 0.14458805949446302 0.42639228822902026 2.4963419700855374 0.04471125610489754 0.30001444352800394 8.727345062265807e-06 5.059117852533868 -0.4787729559932081 TPQNVPAS(ph)PGGDR ddPTM_PC-9_Lapatinib_30min_R1 1 TPQNVPASPGGDR 13 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 TPQNVPAS(1)PGGDR 77.726 0.015795 4497500.0 8391.4 8095.5 10376.0 9327.9 8460.8 8534.0 5246.6 6572.9 12177.0 6087.5 True False 8271.737097205709 8076.755367136038 9522.925332518269 10013.904882962208 7963.152378572807 8169.020713725643 5518.24327618904 6878.300929551163 10805.498030505338 7139.7162639161215 1.1585526359094662 1.1312431851046632 1.3337960474209323 1.4025634230833703 1.1153317700898429 1.1441660160938874 0.7728939179387353 0.9633857530605043 1.513435216622816 1.0 12.80165102659506 -6.467984620453455 7.014327017670164 1.0648321926984536 1.2545013497869182 0.16439068851392202 0.1897148037110987 0.46670359577317955 50.58701224177419 0.06165598936807759 0.06932499532274976 3.404202446925227e-07 6.467984620453455 0.18966915708846455 TPQPS(ph)SPMDQMGK ddPTM_PC-9_AZD4547_30min_R2 1 TPQPSSPMDQMGK 13 0 O14497-2;O14497 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 T(0.001)PQPS(0.642)S(0.357)PMDQMGK 76.311 0.01039 4890100.0 10813.0 10418.0 13519.0 18903.0 16362.0 15369.0 13190.0 16722.0 12813.0 13689.0 True False 14251.309075628033 13785.414764906225 13339.729226842313 14545.2053984387 14090.418728678356 14407.974000422726 14363.884447584229 14137.999133332705 13490.269021742064 13209.752276607325 1.0788475648302023 1.043578598314695 1.0098394691674242 1.1010960004296433 1.0666679006260074 1.0907073576192106 1.0873697058665297 1.0702698156095765 1.021235579537059 1.0 13.689315791428575 -8.389368131870983 3.348031205125684 1.00105879007888 1.0682146524203806 0.4759409019248396 0.02474296624238494 0.2189218115728661 4.35559710036122 0.025242946850613672 0.00675162195643534 4.079734190314287e-09 8.389368131870983 0.0671558623415005 TPQPSS(ph)PMDQMGK ddPTM_PC-9_AZD4547_30min_R2 2 TPQPSSPMDQMGK 13 0 O14497-2;O14497 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 TPQPS(0.244)S(0.756)PMDQMGK;T(0.231)PQPS(0.141)S(0.628)PMDQMGK 101.2 0.0038452 4363500.0 35931.0 32862.0 51521.0 77720.0 64440.0 53374.0 44319.0 65463.0 42882.0 56132.0 True False 47356.310588771885 43483.99884856484 50837.79787677663 59802.85476203023 55493.61831536685 50036.515342479135 48263.30514272064 55347.19754008845 45148.6549746619 54166.83576525112 0.8742676200250137 0.8027790110726851 0.9385410308458498 1.1040492566559463 1.024494370612043 0.9237481687010108 0.891012082593946 1.0217912262764026 0.8335110282300351 1.0 15.72512219568398 -5.396568332415103 5.34269530628407 0.9725223932914714 0.840418359753024 0.33345516868850333 0.07369420539982911 0.25005961857845077 9.72551905630314 0.020079306237702554 0.04283369724414991 4.012653577225107e-06 5.396568332415103 -0.13210403353844735 TPQPSS(ph)PMDQMGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPQPSSPMDQMGK 13 0 O14497-2;O14497 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 TPQPS(0.237)S(0.763)PMDQMGK 104.9 0.00076977 3680900.0 13683.0 12531.0 13865.0 15793.0 16671.0 18704.0 18077.0 18172.0 18557.0 14224.0 True False 15999.261648431275 13774.994865506085 14195.594183305322 14908.169411596831 13404.437223774828 17723.12931348981 16364.615693853555 17695.004254825537 18828.36101860513 16802.698602877947 0.9521840524885056 0.819808483807876 0.8448401366238824 0.8872485166783494 0.7977550237959355 1.0547787431272626 0.9739278243704641 1.0531049013635676 1.1205557787830718 1.0 14.036405335668567 -6.7704410761500124 24.999636086059425 1.039633439451075 0.8587447634814419 0.7445348339577965 0.05274450939270625 97.21065325344858 269973.0951482039 0.018255971790649694 0.0163278126026846 1.6965197656610185e-07 6.7704410761500124 -0.18088867596963298 TPQS(ph)PAPCVLLR ddPTM_PC-9_AZD4547_30min_R2 1 TPQSPAPCVLLR 12 0 Q9Y613 Q9Y613 FHOD1 FH1/FH2 domain-containing protein 1 1 T(0.116)PQS(0.884)PAPCVLLR 76.759 0.018304 4646000.0 10071.0 9924.8 12428.0 20984.0 18908.0 17511.0 11712.0 17235.0 12720.0 15259.0 True False 13273.368510186803 13132.79750995789 12263.196599689054 16146.462999568212 16282.950575837327 16416.034401808978 12754.34531084962 14571.726770899953 13392.35323160533 14724.787054478136 0.9014302523410738 0.891883696611009 0.832826753576687 1.0965498475346516 1.1058190869310616 1.1148571684652306 0.8661819871256297 0.9896052633554634 0.9095108256613067 1.0 13.845959149926422 -5.751269319634484 24.999941906158856 1.0135015057073615 0.8770305658104048 0.3874469664312652 0.07857030664840679 238.4318444187475 586105.3845577317 0.023421852364365985 0.03998817771596948 1.773089591400022e-06 5.751269319634484 -0.1364709398969567 TPQS(ph)PTLPPAK ddPTM_PC-9_Lapatinib_30min_R1 1 TPQSPTLPPAK 11 0 P78310-7;P78310-2;P78310-6;P78310 P78310-7 CXADR Coxsackievirus and adenovirus receptor 1 T(0.154)PQS(0.816)PT(0.03)LPPAK 90.412 0.0087514 4955700.0 103110.0 126550.0 56290.0 50757.0 66911.0 57397.0 53491.0 43968.0 85591.0 36168.0 True False 101639.63249194193 126256.98125020876 51662.05348568362 54489.83910038843 62975.42653208748 54942.26410894201 56260.50224652689 46010.91379307543 75950.84026681294 42419.59060916932 2.396054064462653 2.97638377544637 1.2178819442570592 1.2845442004008882 1.4845835527341196 1.2952096736422962 1.326285837241573 1.0846619010776077 1.7904661307692014 1.0 15.372443077056973 -5.266279038468086 24.999870709788848 1.318792284061585 2.686218966364145 0.8376661764647383 0.24223298857267064 120.92998816478162 624682.3321230919 0.058326816831754634 0.1279569518576771 5.416527613588647e-06 5.266279038468086 1.3674266823025598 TPS(ph)DDEEDNLFAPPK ddPTM_PC-9_AZD4547_30min_R2 1 TPSDDEEDNLFAPPK 15 0 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 T(0.073)PS(0.927)DDEEDNLFAPPK 94.339 0.015879 0.0 3304.6 6152.5 4692.9 4823.7 4822.6 5074.0 4194.8 6424.7 3878.5 4086.3 True False 4355.394060049971 8141.175306305006 4630.669079713612 3711.670490422089 4153.065234135452 4756.72197788697 4568.129073595627 5431.910239918829 4083.5095918853167 3943.239880772922 1.1045217110140055 2.0645904262637047 1.1743310627112915 0.9412743334535757 1.0532114098322118 1.2062978975944512 1.1584710065115844 1.3775246761944673 1.0355721983327324 1.0 11.945165761852637 -5.485341651474565 24.554340976189085 1.1241601381695492 1.5932825647354245 0.3703321881470941 0.24390166285280887 422.41215530931396 276313.7385294242 0.059632563513368604 0.1240782922131128 3.270832832435285e-06 5.485341651474565 0.46912242656587533 TPS(ph)DDEEDNLFAPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPSDDEEDNLFAPPK 15 0 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 T(0.062)PS(0.938)DDEEDNLFAPPK;T(0.289)PS(0.711)DDEEDNLFAPPK 138.28 4.9901e-05 5246000.0 34588.0 38216.0 38303.6 46459.0 54591.0 36457.0 46138.0 39664.0 40287.0 34596.2 True False 40443.06525586063 42009.831919254684 39216.90309121192 43856.052852110224 43894.285434772464 34545.13074111945 41767.4746298067 38622.86202748187 40876.121159484035 40868.21719663151 0.9895970030029615 1.027934047554129 0.9595941732061731 1.073109028492806 1.0740445374355692 0.8452810793020542 1.0220038331706163 0.9450586464697875 1.0001934012147997 1.0 15.318691689272637 TPS(ph)DDEEDNLFAPPK ddPTM_PC-9_Lapatinib_30min_R1 6 TPSDDEEDNLFAPPK 15 0 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 T(0.066)PS(0.934)DDEEDNLFAPPK;T(0.343)PS(0.657)DDEEDNLFAPPK;T(0.037)PS(0.963)DDEEDNLFAPPK;T(0.017)PS(0.983)DDEEDNLFAPPK;T(0.175)PS(0.825)DDEEDNLFAPPK;T(0.089)PS(0.911)DDEEDNLFAPPK 136.81 3.1388e-06 2795500.0 74673.5 83354.5 81690.6 75189.5 83408.5 87219.6 78781.4 79305.7 78184.6 71851.1 True False 73608.64219655709 83161.49777653509 74974.31420283519 80719.18665481903 78502.57601742029 83489.42102681806 82860.31541164924 82990.53234169174 69378.62702766251 84270.46689942744 0.873480887253245 0.986840358625094 0.8896867071154745 0.9578585431495629 0.9315550145356281 0.99073167740317 0.9832663619929726 0.9848115881538518 0.8232851861431172 1.0 16.362739497990198 -5.849140488157896 24.99999880988682 0.9543707411431953 0.923668372236275 0.07911081641691708 0.055268587147865554 64.66025778315161 18417.120889312828 0.015165269612389249 0.022493745581186535 1.415335864646573e-06 5.849140488157896 -0.030702368906920352 TPS(ph)EADRWLEEVSK ddPTM_PC-9_Lapatinib_30min_R1 1 TPSEADRWLEEVSK 14 1 G3V3Z8;P49757-3;P49757;P49757-9;P49757-8;P49757-7;P49757-6;P49757-5;P49757-4;P49757-2 G3V3Z8 NUMB Protein numb homolog 1 T(0.055)PS(0.945)EADRWLEEVSK 85.006 0.034091 3304200.0 8607.7 5567.0 6518.9 5589.5 7146.7 8878.9 5914.9 5797.3 5911.4 6938.2 True False 8484.952619541147 5554.1099535354615 5982.941205681699 6000.570476025395 6726.3451569528015 8499.170144726811 6221.144580172022 6066.663722084159 5245.595882198341 8137.458625429624 1.0427030120958898 0.6825361834933112 0.7352346083806754 0.7374010427866956 0.8265903971459737 1.0444501822923973 0.764507061299322 0.7455231419703673 0.6446233552335138 1.0 12.990362587635998 -10.657025892345033 4.487384029620001 1.0000232643691822 0.800204399170079 0.17107745829464838 0.13024543987349188 188387022.68366772 3.55886598956942 50632.0818424482 0.03194336149061821 2.2027951299738023e-11 10.657025892345033 -0.1998188651991032 TPS(ph)EIQFHQVK ddPTM_PC-9_AZD4547_30min_R2 1 TPSEIQFHQVK 11 0 C9JCU6;Q12851-2;Q12851 C9JCU6 MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 1 T(0.39)PS(0.61)EIQFHQVK 77.527 0.010995999999999999 5180100.0 18415.0 29784.0 35166.0 50770.0 39481.0 33298.0 29975.0 38473.0 22239.0 28239.0 True False 24270.586944205123 39411.095542135445 34699.6758629438 39065.76088868082 33999.74464166667 31215.87079615302 32642.716930730647 32527.881871588885 23414.508138181664 27250.36120528263 0.8906519352668302 1.4462595649739642 1.2733657217070973 1.433586901633719 1.247680512766034 1.145521358817866 1.1978819908046827 1.193667916052547 0.8592366156835615 1.0 14.733987732580896 -8.160366386483728 4.544602186939223 0.9317303504411613 1.2448268620920342 0.3872414541373118 0.15015422165176712 0.21432063019920025 7.088446483405888 0.1090677339083797 0.03803793413829536 6.912475634937857e-09 8.160366386483728 0.31309651165087293 TPS(ph)FELPDASERPPTYCELVPR ddPTM_PC-9_AZD4547_30min_R2 2 TPSFELPDASERPPTYCELVPR 22 1 Q9BRG2;Q9BRG2-2 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 T(0.29)PS(0.341)FELPDAS(0.314)ERPPT(0.03)Y(0.026)CELVPR;T(0.176)PS(0.823)FELPDASERPPTYCELVPR 75.764 0.00040243 49385000.0 3542.1600000000003 1963.4 3637.1000000000004 6337.299999999999 8579.8 2626.1000000000004 5451.0 5035.9 6048.4 7944.3 True False 4668.493198495009 2598.0306536203575 3588.869677561077 4876.333395308978 7388.642868128254 2461.8895518582945 5936.12844001377 4257.717368469688 6368.106075946672 7666.1724750567255 0.6089731497282109 0.3388954086375592 0.46814361263565507 0.6360844882077735 0.9637981524898555 0.3211367289046126 0.7743275355893745 0.555390239695616 0.8306760768384032 1.0 12.904290741202539 -14.522878577291232 0.06651957113233013 2.4691842136143203 0.05334458123318055 0.37432232205248384 0.18001181743731706 368.80708768319516 1.7689978920782685 83.67352778242898 11.473983758293079 3.0000011604278545e-15 14.522878577291232 -2.4158396323811395 TPS(ph)FELPDASERPPTYCELVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSFELPDASERPPTYCELVPR 22 1 Q9BRG2;Q9BRG2-2 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 T(0.196)PS(0.706)FELPDAS(0.08)ERPPT(0.009)Y(0.008)CELVPR 56.453 0.005640699999999999 19193000.0 0.0 2452.4 0.0 1834.6 1878.0 2292.3 2276.6 1632.9 0.0 2073.0 True False 0.0 2695.858064653029 0.0 1731.8133098534502 1510.019381335801 2172.0877526364798 2060.9439668433365 1590.038105200563 0.0 2448.818490141029 0.0 1.1008811292084668 0.0 0.707203623635541 0.6166318113878819 0.8869941816354824 0.8416074834213806 0.6493082731946342 0.0 1.0 11.257870127948213 TPS(ph)FELPDASERPPTYCELVPR ddPTM_PC-9_Lapatinib_30min_R1 1 TPSFELPDASERPPTYCELVPR 22 1 Q9BRG2;Q9BRG2-2 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 T(0.274)PS(0.427)FELPDAS(0.296)ERPPT(0.001)Y(0.001)CELVPR 58.339 0.0046293 16832000.0 0.0 1443.4 0.0 2201.1 1634.5 1434.4 0.0 1687.4 1919.1 2091.7 True False 0.0 1440.057895982231 0.0 2362.976236654351 1538.361923550641 1373.054055749714 0.0 1765.8027641565566 1702.950748981093 2453.2475579849433 0.0 0.5870006438180542 0.0 0.9632033379441169 0.627071621265253 0.559688340983214 0.0 0.7197817270454995 0.6941618033770177 1.0 11.260477108715168 -14.522878743744192 0.08708472316463371 2.764569383088413 7.2285985848211026e-12 0.2812255139296801 0.30867135187504746 331.3601871322979 2.0089765816639957 108.96326717596635 8.25179708510521 3.0000000106113177e-15 14.522878743744192 -2.7645693830811844 TPS(ph)GEFLER ddPTM_PC-9_AZD4547_30min_R2 3 TPSGEFLER 9 0 B3KT28;B1ANM7;Q9UNN5-2;Q9UNN5 B3KT28 FAF1 FAS-associated factor 1 1 T(0.081)PS(0.919)GEFLER;T(0.266)PS(0.734)GEFLER;T(0.412)PS(0.588)GEFLER 112.83 0.0021416 14651100.0 27850.0 25273.0 36164.9 44881.4 42315.8 39909.4 32055.699999999997 43860.2 34180.6 37193.2 True False 36705.72068401374 33442.003009548396 35685.32979627412 34534.6866407177 36440.98159387651 37413.858909003204 34908.595199880634 37082.61389712948 35987.31673492209 35891.07738872902 1.0226976550874045 0.9317636984631251 0.994267444517575 0.9622081350938417 1.0153214738914518 1.0424278575920485 0.9726260045579763 1.0331986832129658 1.002681428176444 1.0 15.13133761058995 -6.2718089913439545 24.51802110176118 1.0123509464500455 0.9756315674608821 0.25154809711805093 0.027998715267847297 664.7860447522402 1571824.1945267927 0.008145358336791721 0.009330819300969361 5.34799519826833e-07 6.2718089913439545 -0.03671937898916344 TPS(ph)GEFLER ddPTM_PC-9_Lapatinib_30min_R1 4 TPSGEFLER 9 0 B3KT28;B1ANM7;Q9UNN5-2;Q9UNN5 B3KT28 FAF1 FAS-associated factor 1 1 T(0.16)PS(0.84)GEFLER;T(0.424)PS(0.576)GEFLER;T(0.194)PS(0.806)GEFLER;T(0.002)PS(0.998)GEFLER 113.69 0.0020846 13829400.0 37726.3 46921.1 60112.6 47853.8 57518.2 58022.2 50378.1 51257.0 63173.4 46967.4 True False 37188.316043843886 46812.45707577382 55170.374069346326 51373.12808759715 54135.092561132136 55540.725762354385 52986.43151606353 53638.58734287819 56058.14644660638 55085.65250987338 0.6750998553966184 0.8498121551230295 1.0015379968396991 0.9326045121892528 0.9827439649812469 1.0082611938271848 0.9618916923343408 0.9737306340024597 1.0176542147078804 1.0 15.749388986036696 -4.854926101928232 1.974552033122867 0.9831653495230596 0.6092624226047799 0.9369467312436541 0.025095371059561253 0.13776484420887616 0.6664068321354475 0.006686513779293459 0.09008919256630345 1.3966059825623042e-05 4.854926101928232 -0.37390292691827964 TPS(ph)IQPSLLPHAAPFAK ddPTM_PC-9_AZD4547_30min_R2 4 TPSIQPSLLPHAAPFAK 17 0 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;H0YF36 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 T(0.136)PS(0.864)IQPS(0.001)LLPHAAPFAK;T(0.248)PS(0.751)IQPSLLPHAAPFAK;T(0.142)PS(0.858)IQPSLLPHAAPFAK;T(0.072)PS(0.928)IQPSLLPHAAPFAK 138.28 1.7043e-05 137267300.0 71137.2 61128.0 230933.0 477208.0 316664.0 237885.0 174675.0 318842.0 195598.0 261138.0 True False 93757.34985432023 80886.43057680818 227870.67753105817 367195.0683901041 272700.66961851896 223010.01334443092 190220.73660968686 269572.2951602713 205936.91095876895 251995.63810422126 0.37205941562982026 0.3209834550523247 0.9042643723730432 1.4571485092064898 1.0821642456594207 0.8849756885561553 0.7548572588030856 1.06974984641909 0.8172241095442963 1.0 17.943039236178386 -5.30521336137459 4.846063939894187 1.0104652522382054 0.34170720586418535 0.6719637919393391 0.18231174201086484 0.11271251417893223 6.30129556705738 0.05189948965576142 0.11780214509443278 4.952068444679735e-06 5.30521336137459 -0.66875804637402 TPS(ph)IQPSLLPHAAPFAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPSIQPSLLPHAAPFAK 17 0 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;H0YF36 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 T(0.154)PS(0.846)IQPSLLPHAAPFAK;T(0.112)PS(0.885)IQPS(0.002)LLPHAAPFAK 110.61 0.00021566 37499200.0 75732.0 68091.0 140787.0 177388.0 199105.0 203323.0 193252.0 212078.0 182561.0 135869.0 True False 88551.9318248189 74850.62448225796 144143.89601767051 167449.52545965527 160091.8045372014 192660.38395031492 174945.77153668142 206511.17721521528 185230.60925351965 160500.97416158768 0.5517220832296469 0.466356200473279 0.8980873590994572 1.0432928917370432 0.9974506720191345 1.2003689382990914 1.0899981912916687 1.2866661918656386 1.1540777881325186 1.0 17.29222252825683 -5.469516187976802 1.4860838553428661 1.1380010865799102 0.45859444373293384 0.8699659318975059 0.09139882849557437 0.14807923151640748 0.597053557269622 0.028195375594493057 0.10022208379590569 3.392218450849025e-06 5.469516187976802 -0.6794066428469763 TPS(ph)IQPSLLPHAAPFAK ddPTM_PC-9_Lapatinib_30min_R1 3 TPSIQPSLLPHAAPFAK 17 0 A0A494C1F2;P35658-2;P35658;A0A0A0MSW3;P35658-4;P35658-3;P35658-5;H0YF36 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 T(0.13)PS(0.87)IQPSLLPHAAPFAK;T(0.113)PS(0.887)IQPSLLPHAAPFAK;T(0.087)PS(0.913)IQPSLLPHAAPFAK 155.53 1.5195e-05 76991200.0 270713.0 176381.3 368204.0 152861.2 285483.7 378696.0 246091.0 251475.0 397793.0 212728.7 True False 266852.5829773158 175972.899936685 337931.6884285425 164103.12257801503 268692.11004854925 362500.05486349267 258832.38784748915 263159.44655462255 352989.3633940054 249498.57235182493 1.0695555508069983 0.7053062399432918 1.354443375138899 0.6577317097694997 1.0769284469879008 1.452914345146317 1.0374102962100413 1.0547533161173124 1.4147951231410063 1.0 17.928672034821652 -6.521177031836579 24.997474883507653 1.1945347635820276 0.947220016444134 0.20428807922144854 0.22813766929279208 102.37262048692637 1503840.3547083635 0.07101339884360848 0.07202529226927215 3.011778080216452e-07 6.521177031836579 -0.2473147471378936 TPS(ph)LRSPDQPPPCPQFMAQGK ddPTM_PC-9_AZD4547_30min_R2 1 TPSLRSPDQPPPCPQFMAQGK 21 1 P49023-3 P49023-3 PXN Paxillin 1 T(0.055)PS(0.473)LRS(0.473)PDQPPPCPQFMAQGK 101.67 0.00035394 0.0 4082.9 4963.8 8522.7 8065.7 6906.3 6729.4 6773.2 9759.7 6466.1 7881.5 True False 5381.177270404299 6568.251277600457 8409.683429366747 6206.277478822785 5947.4794564155545 6308.609554196411 7376.001678572969 8251.56262059486 6807.88484519522 7605.571083941894 0.707530994190023 0.8636105303740315 1.1057267543160072 0.816017286581737 0.7819898585883748 0.8294721704088945 0.9698156255677329 1.0849366246825154 0.8951181666777295 1.0 12.892840865161208 -7.358542401292863 5.111788404165487 0.998086103826901 0.8584665052108238 0.2870153772896542 0.10527791935344336 0.3294730221963854 13.554018083415716 0.04760463281538439 0.031608292100807484 4.379833476364776e-08 7.358542401292863 -0.1396195986160772 TPS(ph)PAAEDAREPEAK ddPTM_PC-9_AZD4547_30min_R2 1 TPSPAAEDAREPEAK 15 1 Q92797 Q92797 SYMPK Symplekin 1 T(0.286)PS(0.714)PAAEDAREPEAK 113.52 0.00099334 6192700.0 8602.7 11296.0 15188.0 13654.0 14582.0 15385.0 15753.0 18790.0 14608.0 15489.0 True False 11338.179652724053 14947.211094680435 14986.597196337092 10506.281252197112 12557.541003641833 14422.973517893384 17154.986482395325 15886.437251245161 15380.14905717693 14946.734824484687 0.7585723427802202 1.000031864497587 1.0026669618696322 0.7029148088575481 0.8401527926400991 0.9649581455253148 1.147741408664937 1.0628700808434173 1.0289972517597792 1.0 13.867542735744282 -6.993130448208487 4.635301585788509 1.0651831903524176 0.8691681620819491 0.4980265825904131 0.0939496525016415 0.1765477915872923 9.949900089170821 0.03689894372028545 0.03076389535060062 1.0159434900203109e-07 6.993130448208487 -0.19601502827046846 TPS(ph)PAAEDAREPEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPSPAAEDAREPEAK 15 1 Q92797 Q92797 SYMPK Symplekin 1 T(0.323)PS(0.677)PAAEDAREPEAK;T(0.311)PS(0.689)PAAEDAREPEAK 113.67 0.00091572 11523200.0 18842.6 35340.0 35025.0 37341.0 42520.0 32590.0 37408.0 31166.0 27992.0 27201.0 True False 22032.280021686107 38848.32164607654 35860.128833052186 35248.90483115541 34188.511232373945 30880.92302858389 33864.44342953331 30347.925523106584 28401.33004433879 32132.325977002478 0.6856733632496724 1.2090105669250581 1.1160140992817558 1.0969920091182788 1.0639911737744447 0.9610547039354004 1.053905760005377 0.944467124627921 0.8838865279988131 1.0 14.971737797147737 -7.797157503189955 6.878392742239031 0.9344421692253052 1.0387485588781362 0.0712437538068591 0.1329844782270959 0.4530489343595692 61.75420233225085 0.07040259061240227 0.034234832298369836 1.595300483464811e-08 7.797157503189955 0.10430638965283101 TPS(ph)PAAEDAREPEAK ddPTM_PC-9_Lapatinib_30min_R1 2 TPSPAAEDAREPEAK 15 1 Q92797 Q92797 SYMPK Symplekin 1 T(0.43)PS(0.57)PAAEDAREPEAK;T(0.101)PS(0.899)PAAEDAREPEAK 156.11 0.00057108 14090500.0 24886.0 36804.0 37880.0 34240.0 32678.0 30571.0 30380.0 30407.0 28524.0 20947.0 True False 24531.121076466527 36718.78259923102 34765.652621028516 36758.12382129164 30755.944287419883 29263.549594481676 31952.92774951836 31819.820226210977 25311.326748963962 24567.66103987695 0.9985126804154814 1.4945982256768764 1.4150981880040885 1.4961995674569006 1.2518873586499923 1.1911410511152283 1.3006092723948783 1.2951912750083412 1.0302701062132016 1.0 14.58447289224362 -8.26809815254865 3.7615181852432604 0.9993457588544111 1.3181289827445812 0.40787073452034495 0.1397289502285482 0.21839146202873158 6.626245166055705 0.12556837720722955 0.03647077654451387 5.3938870441273855e-09 8.26809815254865 0.3187832238901701 TPS(ph)PARPALR ddPTM_PC-9_AZD4547_30min_R2 1 TPSPARPALR 10 1 Q9H211 Q9H211 CDT1 DNA replication factor Cdt1 1 T(0.072)PS(0.928)PARPALR 62.799 0.027335 7332400.0 18578.0 20607.0 26379.0 31919.0 32887.0 25668.0 23162.0 25870.0 18807.0 22097.0 True False 24485.417553594525 27267.80975815154 26029.197224267602 24560.567693634082 28321.20772094152 24062.975902326143 25223.373129260475 21872.385933459947 19801.099624748527 21323.390755803335 1.1482891175237042 1.2787745659414125 1.2206875314698036 1.1518134228698933 1.3281756192191747 1.1284779319526004 1.1828969143847692 1.0257461481592556 0.9286093310164331 1.0 14.380149247178569 -7.786421261214541 2.017154587757675 0.9592309226110022 1.215566952655909 0.7457547319989485 0.059809060879618764 0.15685022450787175 1.242909880681117 0.04141150248623489 0.016690025459506215 1.635229595884455e-08 7.786421261214541 0.2563360300449068 TPS(ph)PARPALR ddPTM_PC-9_Lapatinib_30min_R1 1 TPSPARPALR 10 1 Q9H211 Q9H211 CDT1 DNA replication factor Cdt1 1 T(0.001)PS(0.999)PARPALR 56.551 0.040163 6603400.0 19179.0 20321.0 20696.0 16990.0 17317.0 16193.0 14048.0 19336.0 18930.0 14888.0 True False 18905.503943002146 20273.947973018527 18994.45476887028 18239.501276978535 16298.448106531927 15500.463137726658 14775.336702608094 20234.421149538444 16797.904058262782 17461.37096298697 1.0827044441743043 1.1610742372974838 1.0877985931994116 1.0445629564620655 0.9334002548299271 0.8877002367444763 0.8461727738290145 1.1588105648994877 0.9620037334908843 1.0 14.091879214797144 -5.936536747355717 2.556902629323856 0.9634998980915025 1.118587359620311 0.4022601300968386 0.08003227573417543 0.2970451240854905 3.9358616938290667 0.02595146031368456 0.04119662520481577 1.1573461003662978e-06 5.936536747355717 0.1550874615288086 TPS(ph)PEPVDKDFYSEFGNK ddPTM_PC-9_Lapatinib_30min_R1 1 TPSPEPVDKDFYSEFGNK 18 1 Q9Y2I1;Q9Y2I1-2 Q9Y2I1 NISCH Nischarin 1 T(0.166)PS(0.834)PEPVDKDFYSEFGNK 61.861999999999995 0.010528000000000001 2903700.0 14269.0 12936.0 12989.0 15866.0 14636.0 13190.0 12750.0 14451.0 14757.0 15188.0 True False 14065.521443385876 12906.047486785472 11921.094558989957 17032.83856742444 13775.13925548313 12625.89444739176 13410.132613770867 15122.446215969185 13094.911261900896 17813.2255632621 0.7896111455745853 0.7245205221789159 0.6692271714998073 0.9561905847390644 0.7733096516721205 0.7087932728720022 0.7528188853919782 0.8489448562958544 0.7351229689084366 1.0 14.120661158357082 -11.201683454689155 2.466626463359399 1.0364822555791893 0.7738065286830127 0.44101113235871137 0.07660895794969798 9317785.15737621 7279832.3449598225 2127602.4200438904 0.019889853792436754 6.285163001584068e-12 11.201683454689155 -0.2626757268961766 TPS(ph)PESHR ddPTM_PC-9_AZD4547_30min_R2 1 TPSPESHR 8 0 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 T(0.177)PS(0.823)PESHR 93.561 0.0040421 5881900.0 19948.0 15519.0 16484.0 21715.0 19451.0 22121.0 12972.0 17092.0 14695.0 13205.0 True False 26291.049055824256 20535.21325941444 16265.411389545743 16708.942243405625 16750.564398699586 20737.77037304644 14126.482869906178 14450.824135086872 15471.747699562902 12742.696969289187 2.0632248510019164 1.611528023377294 1.276449673781504 1.3112563442162497 1.3145226979084292 1.6274239608009164 1.1085944289464007 1.1340475387521491 1.2141658658956518 1.0 13.63738303331622 -1.522878745783487 0.7006807603555644 1.229737900073804 107.31522338995157 0.7322884535005901 0.1556947456613447 156.9715147212593 0.8308430621717737 0.06401972545171346 26091.165947008816 0.029999999965243673 1.522878745783487 106.08548548987777 up TPS(ph)PESHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSPESHR 8 0 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 T(0.116)PS(0.884)PESHR 86.344 0.0071101 5390300.0 19766.0 23918.0 16532.0 17297.0 21278.0 12027.0 15630.0 10292.0 15766.0 14016.0 True False 23111.99340370478 26292.420971444775 16926.18557795914 16327.905167630615 17108.728645401054 11396.282947676544 14149.413248599392 10021.845905275395 15996.54792365838 16556.98984940505 1.3959055126518225 1.5879952340726688 1.0222984813007756 0.9861638689243585 1.033323617457906 0.6883064525213833 0.8545885077720108 0.6052939572005303 0.9661507356805676 1.0 14.015152786439971 -5.475796620805648 1.2139600141863065 0.8255842239225494 1.5580183141499657 0.7186065757653186 0.14791841362325778 0.2968885126856928 0.7511516369636155 0.047926565936356365 0.20141448970163092 3.3435157951262584e-06 5.475796620805648 0.7324340902274163 TPS(ph)PGPVESK ddPTM_PC-9_AZD4547_30min_R2 2 TPSPGPVESK 10 0 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 T(0.121)PS(0.879)PGPVESK;T(0.033)PS(0.967)PGPVESK 117.95 0.00091417 134296000.0 99273.0 113500.0 140938.0 163597.0 168128.0 142793.0 154132.0 172200.0 132039.0 156047.0 True False 130839.74899332468 150186.65538652884 139069.07003274665 125882.2391984541 144786.32930052737 133864.1311368577 167849.44940675134 145590.4467623427 139018.3119770391 150583.84202700987 0.8688830569873245 0.9973623555148116 0.9235324863593409 0.8359611330402561 0.961499768843442 0.8889674306015303 1.1146577690363657 0.9668397671526304 0.9231954113118173 1.0 17.200207448443194 TPS(ph)PGPVESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPSPGPVESK 10 0 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 T(0.108)PS(0.892)PGPVESK;T(0.122)PS(0.878)PGPVESK 86.911 0.010964 77329000.0 87161.0 104405.0 100895.0 123726.0 126940.0 116049.0 122733.0 119254.0 102174.0 89383.0 True False 101915.63579177961 114769.638411393 103300.7194464183 116794.03334510404 102067.01824641446 109963.18614741116 111106.84173002862 116123.70886005761 103668.10145578292 105587.4303445613 0.9652250789625281 1.0869630791929266 0.9783429628822216 1.1061357679031723 0.9666587955909264 1.0414420143436633 1.0522733754146296 1.0997872424881776 0.9818223733401308 1.0 16.688078573726777 -6.952093246073307 24.999958092437332 1.0425116182158798 1.0244760251367984 0.005934099502986956 0.053311277237145946 556.7428566487342 290531.8455163026 0.01764461594979261 0.015561087878679596 1.11662347514405e-07 6.952093246073307 -0.018035593079081425 TPS(ph)PGPVESK ddPTM_PC-9_Lapatinib_30min_R1 3 TPSPGPVESK 10 0 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 T(0.358)PS(0.641)PGPVESK;T(0.435)PS(0.565)PGPVESK;T(0.014)PS(0.986)PGPVESK 126.66 0.00033883 95630000.0 249457.0 236987.0 257851.0 232519.0 228066.0 239014.0 191928.0 191376.0 224969.0 169329.0 True False 245899.6974351891 236438.27116193826 236651.48611364354 249619.22292064613 214651.60627500794 228791.92838884727 201865.09272908344 200268.02761243636 199630.62219140603 198597.29203329017 1.2381825296689835 1.1905412643909814 1.191614868917621 1.2569115135709068 1.0808385354973855 1.1520395169864435 1.016454407118731 1.0084126805659874 1.0052031432429736 1.0 17.599486425617407 -6.929845590220508 0.9602442253889094 0.9940790633400957 1.2174930624229447 0.849418170312159 0.037975461932114686 0.1944284237597587 0.37655090766086846 0.023443579185834167 0.01812045379255155 1.1753153542305203e-07 6.929845590220508 0.2234139990828491 TPS(ph)PNSNEQQK ddPTM_PC-9_AZD4547_30min_R2 3 TPSPNSNEQQK 11 0 Q9H4E7 Q9H4E7 DEF6 Differentially expressed in FDCP 6 homolog 1 T(0.022)PS(0.978)PNSNEQQK;T(0.095)PS(0.863)PNS(0.042)NEQQK;T(0.031)PS(0.966)PNS(0.003)NEQQK 141.34 0.00013014 38417000.0 47022.3 50447.4 59025.4 77948.1 63097.7 65044.1 56731.9 65568.3 56130.7 61048.3 True False 61974.413275400286 66753.53549732488 58242.68462948876 59978.36983114002 54337.67350058233 60976.882144635005 61780.929195747034 55436.225844641776 59097.65420890479 58911.01759865638 1.0520003863727823 1.1331248078601748 0.9886552126170901 1.018118041004744 0.9223686114330785 1.0350675413562325 1.0487160418216255 0.9410162666398441 1.0031681104461632 1.0 15.846249853138268 -5.274543594906161 24.69460731591642 0.9941648517190993 1.0925625958403389 0.47971464576332434 0.040789878162246995 473.3266470754182 891974.2164757344 0.010547903268765627 0.022175505481441937 5.314426500944674e-06 5.274543594906161 0.09839774412123958 TPS(ph)PNSNEQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TPSPNSNEQQK 11 0 Q9H4E7 Q9H4E7 DEF6 Differentially expressed in FDCP 6 homolog 1 T(0.464)PS(0.536)PNSNEQQK;T(0.01)PS(0.99)PNSNEQQK;T(0.003)PS(0.995)PNS(0.002)NEQQK;T(0.456)PS(0.543)PNSNEQQK 157.03 0.00016456 40290300.0 63069.0 66384.0 62619.0 65181.0 85598.0 65566.2 74226.0 61141.4 63246.0 58209.8 True False 73745.33603046932 72974.16480342798 64112.07444387993 61529.11988965323 68825.68637038431 62127.793049301596 67194.77593029692 59536.503034668145 64170.85310032334 68762.77595147678 1.072460135735482 1.0612451838029782 0.9323660011794946 0.8948027335759676 1.0009148906226812 0.9035090888876093 0.9771969644988396 0.8658246007502771 0.9332208046051865 1.0 16.06934016710234 -5.25176945103211 6.646290246681732 0.9343616310767917 1.0678991661520256 0.5953305470103977 0.04223808739904879 0.08828471432079146 21.406042656032056 0.010367901943465868 0.025481893750960535 5.6005483252795715e-06 5.25176945103211 0.13353753507523392 TPS(ph)PNSNEQQK ddPTM_PC-9_Lapatinib_30min_R1 3 TPSPNSNEQQK 11 0 Q9H4E7 Q9H4E7 DEF6 Differentially expressed in FDCP 6 homolog 1 T(0.02)PS(0.98)PNS(0.001)NEQQK;T(0.063)PS(0.937)PNSNEQQK;T(0.007)PS(0.993)PNSNEQQK 151.55 8.696200000000001e-05 33858000.0 51282.4 52472.9 56203.2 47296.4 55897.7 51522.7 49283.5 52144.5 53399.4 35939.8 True False 50551.1035719596 52351.4022239754 51582.38984662591 50774.735032165234 52609.90718510653 49319.194226279855 51835.15848398249 54567.323832856244 47384.99725138919 42151.946543226695 1.1992590548604818 1.2419687942593396 1.2237249777712715 1.2045644198209422 1.2481014875826726 1.1700336110386544 1.229721584288538 1.2945386466766753 1.1241473084237288 1.0 15.36331163475992 -8.539901388786207 5.120367144571164 1.0000954530190673 1.2247013752959772 0.8378738011785217 0.03137643272593995 0.05661667602948375 6.5414325427411635 0.029710041134646557 0.007723736233383939 2.8846864277209184e-09 8.539901388786207 0.2246059222769099 TPS(ph)PPPPIPEDIALGK ddPTM_PC-9_AZD4547_30min_R2 3 TPSPPPPIPEDIALGK 16 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 T(0.011)PS(0.989)PPPPIPEDIALGK;T(0.123)PS(0.877)PPPPIPEDIALGK;T(0.138)PS(0.862)PPPPIPEDIALGK 132.15 7.6174e-06 8588600.0 16811.4 19176.6 21261.0 20674.3 25905.800000000003 19439.5 18285.399999999998 18746.4 21619.2 21654.800000000003 True False 22157.075501157222 25375.060931148073 20979.065248309395 15908.15954975091 22309.226836657854 18223.944991945966 19912.765176486475 15849.574629416833 22761.946775528453 20896.672043208146 1.0603159898065555 1.2143111055521159 1.003942886452488 0.7612771792971404 1.0675971174036212 0.8720979567590585 0.9529156190666513 0.7584736266446922 1.0892618082182401 1.0 14.350985579795518 -5.51569655861343 24.746529240053373 0.9200451625427642 1.130266949717715 0.3543143485468232 0.11110680477952552 261.79216814991827 902014.6749268499 0.02774715899322634 0.05068798111513925 3.0500252968143933e-06 5.51569655861343 0.21022178717495066 TPS(ph)PPPPIPEDIALGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TPSPPPPIPEDIALGK 16 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 T(0.08)PS(0.92)PPPPIPEDIALGK;T(0.054)PS(0.946)PPPPIPEDIALGK;T(0.479)PS(0.521)PPPPIPEDIALGK;T(0.349)PS(0.651)PPPPIPEDIALGK 107.82 0.00086385 9984000.0 27017.2 35327.2 25106.1 25931.5 31939.0 24671.2 29986.300000000003 29545.199999999997 18677.7 21527.800000000003 True False 31590.678345976557 38834.25094666879 25704.72463941447 24478.642126057322 25680.7822260299 23377.398840834572 27145.780581988212 28769.669805727008 18950.826027763174 25430.61972602898 1.242229984416879 1.5270666371893722 1.010778538483863 0.9625656940244645 1.0098370587384808 0.9192618619870724 1.0674447132801768 1.1313003818102165 0.745197176943606 1.0 14.634278999452995 -5.286900929147193 15.21451565515573 0.9867615708092863 1.384637926005786 0.6625775963649767 0.11521577412920189 2.8774756267009542 1719.7194051912861 0.028527835470493597 0.05972606835635122 5.165341871310937e-06 5.286900929147193 0.39787635519649966 TPS(ph)PPPPIPEDIALGK ddPTM_PC-9_Lapatinib_30min_R1 2 TPSPPPPIPEDIALGK 16 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 T(0.062)PS(0.938)PPPPIPEDIALGK;T(0.093)PS(0.907)PPPPIPEDIALGK 96.666 0.0022941 3872500.0 7156.200000000001 9191.8 12387.2 13827.5 12580.0 10345.7 13630.3 12743.3 9660.6 11114.8 True False 7054.15127571365 9170.516951842512 11368.772231974786 14844.420477187794 11840.069133231604 9903.238528004616 14336.010240429889 13335.40023970384 8572.521497372081 13035.978370459947 0.5411294093352166 0.7034774599368218 0.8721073255028471 1.1387269950390413 0.9082608759202668 0.7596850996965256 1.0997264519029786 1.0229688835570943 0.6576047653467852 1.0 13.670211242993853 -5.116102498434167 2.3486954656494414 0.9424353028474544 0.549096834392894 0.46695206148649737 0.13851190673989844 0.30112294749211643 2.9458403710628365 0.03778328343312226 0.1781832013709262 7.654159387305293e-06 5.116102498434167 -0.39333846845456033 TPS(ph)PPPPIPEDIALGKK ddPTM_PC-9_AZD4547_30min_R2 2 TPSPPPPIPEDIALGKK 17 1 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 T(0.074)PS(0.926)PPPPIPEDIALGKK;T(0.046)PS(0.954)PPPPIPEDIALGKK 78.55199999999999 0.0031910999999999997 14810100.0 115056.0 92623.0 135418.0 194411.0 179308.0 143031.0 111369.0 116678.0 113650.0 143921.0 True False 151641.41468653118 122561.57340851505 133622.26883945055 149592.54757000846 154414.17928137523 134087.24895923346 121280.62524965954 98648.09609370836 119657.3069789266 138882.36959614328 1.0918694369018183 0.8824847514116618 0.9621254967639982 1.077116901194942 1.1118342791125826 0.9654735107785561 0.873261491738167 0.710299632563641 0.8615730515462737 1.0 17.083503942650395 -7.230900358781259 3.3352861668782716 0.8334375265226692 1.0173845219537265 0.4013116520361516 0.09186308792978236 0.23354959632949213 5.388900009550937 0.03990940819230651 0.028314449450659075 5.876241570767161e-08 7.230900358781259 0.1839469954310573 TPS(ph)PPPPIPEDIALGKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSPPPPIPEDIALGKK 17 1 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 T(0.042)PS(0.958)PPPPIPEDIALGKK 84.436 0.0015611 4153900.0 51257.0 25802.0 40154.0 53833.0 66336.0 65947.0 58246.0 67798.0 61465.0 45806.0 True False 59933.79772810361 28363.452040522545 41111.423644892995 50816.911538940796 53337.93699696038 62488.623226941476 52728.5172154779 66018.37433791901 62363.80934464427 54110.26519990352 1.1076234334961357 0.5241787660019289 0.7597712466019534 0.9391362498632034 0.9857267710647901 1.1548386058742306 0.9744642171070327 1.2200711656840433 1.1525319477598026 1.0 15.723614691682013 -6.177878454656362 1.7550793277910433 1.1040433972330153 0.7739443983153238 0.41629988462718837 0.15138652353191728 0.31587640223465085 1.924141938181066 0.051119044373667356 0.07259203663928765 6.639288571737267e-07 6.177878454656362 -0.33009899891769146 TPS(ph)PPPPIPEDIALGKK ddPTM_PC-9_Lapatinib_30min_R1 2 TPSPPPPIPEDIALGKK 17 1 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 T(0.017)PS(0.983)PPPPIPEDIALGKK;T(0.154)PS(0.846)PPPPIPEDIALGKK 121.95 2.9715999999999998e-05 12480700.0 134955.0 83301.0 89566.0 74496.0 83158.0 85964.0 61078.0 67331.0 90083.0 64104.0 True False 133030.5169522838 83108.12165249804 82202.22921475842 79974.68435137109 78266.80993491838 82287.52011187145 64240.31998305074 70459.44406390026 79936.90392395598 75184.29098678911 1.7693924516181052 1.1053921046765107 1.0933431457005087 1.0637153493330636 1.040999508110955 1.0944775701393588 0.8544380633228106 0.937156460999026 1.063212845060971 1.0 16.198143636094258 -2.5827191857746508 1.2433842731141986 1.0053319148420954 199.99977715562804 0.9034642891780366 0.07293961315321323 112.65894844616004 0.8954917070648155 0.022776204188528156 63182.041652380576 0.002613850920579166 2.5827191857746508 198.99444524078595 TPS(ph)PSPPCSSSPSPSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSPSPPCSSSPSPSGR 17 0 O75385 O75385 ULK1 Serine/threonine-protein kinase ULK1 1 T(0.437)PS(0.531)PS(0.031)PPCS(0.001)SSPSPSGR 126.91 5.0045e-05 0.0 7887.4 8775.4 13228.0 14477.0 13033.0 9483.1 8476.5 7536.8 11957.0 9757.8 True False 9222.581036749014 9646.563717401808 13543.405687469367 13665.900625067274 10479.277208173322 8985.789541956552 7673.544555454431 7338.966985899685 12131.848504578411 11526.8118972977 0.8000981640822228 0.8368804664595342 1.1749480956347027 1.1855750529138982 0.9091219065204006 0.7795554939230981 0.6657126553139455 0.6366866269085386 1.0524895012316937 1.0 13.492705924979504 -6.562991999992709 5.065869306629918 0.7966687022697355 1.0058422681425054 0.17782387509298314 0.1679336447169119 0.29205373613868035 17.860151377370926 0.05896129871831711 0.059937735714122135 2.735319112328658e-07 6.562991999992709 0.20917356587276992 TPS(ph)PSQPKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSPSQPKK 9 1 Q9NTI5-2;Q9NTI5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 T(0.253)PS(0.65)PS(0.097)QPKK 60.641000000000005 0.031712 8871400.0 43156.0 30204.0 28609.0 47941.0 44234.0 40532.0 46369.0 47649.0 44753.0 31162.0 True False 50461.458430146886 33202.45350871804 29291.147060236683 45255.02119681905 35566.6652364259 38406.43056749192 41976.59263751152 46398.264238288706 45407.42796064211 36811.42392174374 1.3708097393195473 0.9019605864555009 0.7957080693891607 1.2293743728312516 0.966185532839913 1.0433291211211757 1.1403142874002443 1.2604311187995696 1.2335145757244366 1.0 15.167865935984446 -7.359674506500383 3.6785359947993364 1.1870565033775853 1.0367512341214875 0.0838803823206048 0.16518816184639756 0.4939853292620169 12.335005199727997 0.07362414985629304 0.047826961023836684 4.368431132189926e-08 7.359674506500383 -0.15030526925609777 TPS(ph)SCSSSLDSIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSSCSSSLDSIK 13 0 Q8NG31-2;Q8NG31;H0YCZ2;H0YEY7 Q8NG31-2 CASC5 Protein CASC5 1 T(0.331)PS(0.624)S(0.026)CS(0.008)S(0.008)S(0.002)LDSIK 88.28200000000001 0.028406999999999998 0.0 12318.0 14140.0 13658.0 12878.0 14331.0 9991.2 17531.0 12545.0 13973.0 9407.5 True False 14403.194108410175 15543.72575199553 13983.658518253445 12156.487411039327 11522.943425944286 9467.24388349762 15870.336766551236 12215.707042526208 14177.328690681115 11113.005280270976 1.2960665225256667 1.398696874516064 1.2583147551525748 1.093897384591444 1.0368881445958706 0.8519067205254467 1.428086855562464 1.0992262429869326 1.2757420997405862 1.0 13.439961395794041 -5.59495050851582 3.7904548888156415 1.1159538574775028 1.345332888475768 0.2987815172749232 0.14796827264511456 0.28256844628834554 8.023534527223921 0.04182830191801531 0.07856953186762143 2.5412622871154373e-06 5.59495050851582 0.2293790309982653 TPS(ph)SEEISPTK ddPTM_PC-9_AZD4547_30min_R2 1 TPSSEEISPTK 11 0 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 T(0.052)PS(0.474)S(0.474)EEISPTK 130.15 0.00022343 6395200.0 20452.0 29194.0 27389.0 29650.0 27621.0 29014.0 32910.0 33103.0 28858.0 26748.0 True False 26955.310571973037 38630.389580214294 27025.80396434531 22814.650587933545 23786.300923164945 27199.749993380497 35838.92624488224 27987.69198126494 30383.374965225335 25811.560661457577 1.0443115364280677 1.49663129970665 1.0470426146955487 0.8838927210628109 0.9215367189587728 1.053781689148142 1.3884835060902676 1.0843083976342744 1.1771227382850389 1.0 14.655729754242675 -1.5359852888622731 0.008765143305288322 3.9652922753259565e-07 2.3562859441134654 0.017221067295748682 0.18343590603584364 118318.90708000575 80.6318919670111 9517.634449214685 12325.99287491729 0.02910815716339055 1.5359852888622731 2.3562855475842377 TPS(ph)SEEISPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSSEEISPTK 11 0 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 T(0.004)PS(0.667)S(0.33)EEISPTK 148.89 0.00029502 41636000.0 52597.0 68012.0 52837.0 50005.0 69579.0 41022.0 54311.0 40715.0 32255.0 36398.0 True False 61500.63326189724 74763.78188435092 54096.83446543835 47203.38196839737 55945.49442703069 38870.734104896226 49166.26890241085 39646.27439110841 32726.668354535126 42996.66927359055 1.4303580789145498 1.7388272893563963 1.2581633735677695 1.0978381062039768 1.301158796069666 0.9040405864361089 1.1434901757055351 0.9220778041861019 0.7611442678569645 1.0 15.39193728567613 -5.660790587466394 0.5616812120787773 0.9093929453302241 1.7434491194611674 0.691609286747845 0.15192669746082346 0.9428348191313508 0.4403187205894566 0.09812388963691598 0.45958965637285804 2.1837826565592666e-06 5.660790587466394 0.8340561741309434 TPS(ph)SEEISPTK ddPTM_PC-9_Lapatinib_30min_R1 3 TPSSEEISPTK 11 0 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 T(0.004)PS(0.961)S(0.036)EEISPTK;T(0.022)PS(0.486)S(0.486)EEIS(0.006)PTK;T(0.055)PS(0.936)S(0.009)EEISPTK 151.7 0.00036947 100222000.0 100123.0 211819.0 203576.0 182619.0 212851.0 198576.0 209353.0 210910.0 185375.0 163939.0 True False 98695.22765969069 211328.54611962035 186838.76710608485 196049.41045912512 200331.52266116682 190083.36738326485 220192.27396790354 220709.64856480918 164496.1154147102 192275.63771501376 0.5133007427907967 1.09909164068329 0.9717235596067179 1.0196268897555538 1.0418975853721693 0.9885982937942547 1.1451907094661007 1.1478815058824021 0.8555224019515271 1.0 17.552816452016792 -4.757157661468848 24.99998228144663 1.0351099010818432 0.5132999758111794 0.7769944365540583 0.08299413721162506 56.7200103403738 331132.4663147491 0.020164915492831587 0.15332365137414228 1.7492115589144943e-05 4.757157661468848 -0.5218099252706638 TPS(ph)SEEISPTKFPGLYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPSSEEISPTKFPGLYR 17 1 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 T(0.283)PS(0.637)S(0.08)EEISPTKFPGLYR;T(0.379)PS(0.607)S(0.014)EEISPTKFPGLYR 173.19 3.4379000000000004e-05 54529000.0 93493.0 79785.0 97068.0 116406.0 137439.0 95362.0 122325.0 107525.0 118015.0 100591.0 True False 109319.51832907897 87705.52751930445 99382.46925243973 109884.1492133437 110508.81456411665 90361.04884479352 110737.49044369315 104702.5826821549 119740.74611255515 118827.35202208204 0.9199861519152914 0.7380920808788693 0.8363602113591758 0.9247378431265859 0.9299947586442932 0.7604398087403434 0.9319191967108253 0.8811320028632609 1.007686732683426 1.0 16.858507432500467 -8.111928887734015 1.5384058046375828 1.010068408147915 0.8551200015057071 0.40847426622172156 0.06622296925926136 0.39975072645778753 1.70221826140688 0.06113011146484579 0.019434444498968688 7.728071157526566e-09 8.111928887734015 -0.15494840664220788 TPS(ph)SEEISPTKFPGLYR ddPTM_PC-9_Lapatinib_30min_R1 1 TPSSEEISPTKFPGLYR 17 1 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 T(0.289)PS(0.422)S(0.289)EEISPTKFPGLYR 125.36 0.00018648 14591000.0 74076.0 40389.0 42639.0 50037.0 39935.0 41336.0 27662.0 34988.0 49253.0 34001.0 True False 73019.66265612544 40295.48175199277 39133.38601129977 53716.8878985388 37586.101815230846 39568.15563892236 29094.203008794506 36613.670209973694 43705.6084829169 39878.027546515346 1.8310750844171604 1.0104682761701411 0.9813270218957797 1.3470297104309195 0.9425266024351103 0.9922295076597875 0.7295797911483423 0.9181414543953065 1.0959822030298993 1.0 15.283306432233514 -4.7614475392898274 7.665376910277091 0.9980534962507412 1.8434323183475343 0.7437047682237901 0.14602714025846497 0.05204163270593387 23.41582206666549 0.038633726726117194 0.228353195634428 1.7320182376889178e-05 4.7614475392898274 0.845378822096793 TPS(ph)SPCPASK ddPTM_PC-9_AZD4547_30min_R2 1 TPSSPCPASK 10 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 T(0.091)PS(0.841)S(0.068)PCPASK 101.35 0.0036361999999999996 37396000.0 65803.0 60655.0 96278.0 105630.0 103450.0 84383.0 85283.0 97870.0 80679.0 91458.0 True False 86726.9852125727 80260.5425768274 95001.29081307224 81278.6354672316 89087.75317698196 79106.51767048403 92873.02178493753 82746.44032886428 84943.52723055705 88256.08325764856 0.982674304267368 0.9094052173437208 1.0764276784834446 0.9209408855132682 1.0094233721760062 0.8963293492137654 1.0523129778353137 0.9375720887964196 0.962466541627266 1.0 16.42940810250179 -10.731281438303455 5.983947010615698 1.0000005147742153 0.9719137886803427 0.021389286249614226 0.05691845833591246 3.5792026633358125e-07 4.7374058680236e-08 0.05046135543265856 0.012238452064960832 1.856600921597105e-11 10.731281438303455 -0.028086726093872527 TPS(ph)SPCPASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSSPCPASK 10 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 TPS(0.61)S(0.389)PCPASK 129.82 0.00023366 10492000.0 55422.0 56809.0 64433.0 67709.0 78228.0 60891.0 76250.0 67892.0 59270.0 59136.0 True False 64803.84996560387 62448.62208239843 65969.32708351326 63915.48424553975 62899.784964396706 57697.76876752078 69027.0479978058 66109.90693751996 60136.71162217632 69856.8886796816 0.927665849287281 0.893950808040526 0.9443496315160245 0.9149489113180338 0.9004091959035614 0.8259424354280269 0.9881208468118169 0.9463620293863522 0.8608558548595586 1.0 16.092114768254856 -11.28167638455494 3.220689849456739 1.0146423796013648 0.912408839581463 0.27327481030257816 0.04331675115601669 89887725.93170509 40843393.92433183 10074453.546504222 0.010838178021527324 5.2278559868290915e-12 11.28167638455494 -0.10223354001990181 TPS(ph)SPCPASK ddPTM_PC-9_Lapatinib_30min_R1 1 TPSSPCPASK 10 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 TPS(1)SPCPASK 155.33 0.00027257 31644000.0 61924.0 55326.0 62136.0 52517.0 62273.0 50058.0 47808.0 54552.0 62756.0 41760.0 True False 61040.95240452921 55197.89604621929 57027.41793189623 56379.27537157633 58610.22457342861 47917.13603089738 50283.264313659456 57086.6850718671 55687.75843002319 48978.16035829769 1.2462892023299093 1.1269899817065685 1.164343811909523 1.1511105145464038 1.1966603919924301 0.9783367868527845 1.0266466511974792 1.1655538847162048 1.1369916310176151 1.0 15.57985096619524 -6.734375955864365 24.999630882424945 1.0696741514758172 1.1721459177550084 0.4681874966919075 0.06116663268887164 236.98592014857365 218913.27468280485 0.021217353324404116 0.02121217053368553 1.843418935115078e-07 6.734375955864365 0.10247176627919119 TPS(ph)SPLQSCTPSLSPR ddPTM_PC-9_AZD4547_30min_R2 1 TPSSPLQSCTPSLSPR 16 0 R4GNJ5;A0A590TQL1;Q96AP0-2;Q96AP0 R4GNJ5 ACD Adrenocortical dysplasia protein homolog 1 T(0.008)PS(0.939)S(0.053)PLQSCTPSLSPR 223.14 1.5985e-28 14735000.0 15422.0 15428.0 31046.0 37522.0 22874.0 16265.0 17006.0 23114.0 17635.0 24682.0 True False 20325.875202472515 20414.79928901644 30634.30975490395 28871.88260912114 19698.33993398049 15247.946978780363 18519.501055012686 19542.26240688028 18567.15009743395 23817.8906926161 0.8533868706003357 0.8571203702494667 1.2861890311891069 1.2121930939112024 0.8270396479771933 0.6401888049434811 0.777545807645931 0.8204866946063646 0.779546364413791 1.0 14.53975803363955 -6.404988262094887 6.836034133062081 0.7847767233207643 1.053959192629756 0.38557473596501235 0.1505693666606647 0.26575174372287347 13.969098145236226 0.05019421118344224 0.056869616353969726 3.935607122841562e-07 6.404988262094887 0.2691824693089917 TPS(ph)SPLQSCTPSLSPR ddPTM_PC-9_Lapatinib_30min_R1 1 TPSSPLQSCTPSLSPR 16 0 R4GNJ5;A0A590TQL1;Q96AP0-2;Q96AP0 R4GNJ5 ACD Adrenocortical dysplasia protein homolog 1 T(0.003)PS(0.928)S(0.07)PLQSCTPSLSPR 173.19 1.4808e-05 11808000.0 17591.0 16670.0 17273.0 17249.0 20848.0 24003.0 20124.0 18622.0 27338.0 23124.0 True False 17340.149114205677 16631.401639201747 15852.880615708174 18517.549000977207 19621.761628745026 22976.447643725893 21165.92225251177 19487.246102953308 24258.906558097624 27120.952589206805 0.6393635716581154 0.6132307331203575 0.5845252139859228 0.6827764968825818 0.7234908716500542 0.847184388828205 0.7804269478696361 0.7185310338512428 0.8944710359381634 1.0 14.72712023175487 -6.991198841751531 0.1542664811193575 1.1196951354939848 0.37650087668402077 0.8234545511201646 0.052857890240159036 3.465805509307514 0.28524366059680295 0.4316066168907535 0.7941632042203651 1.0204721535027581e-07 6.991198841751531 -0.743194258809964 TPS(ph)SSSTLAYSPR ddPTM_PC-9_AZD4547_30min_R2 1 TPSSSSTLAYSPR 13 0 A0A087WUB0;H3BR17;Q6Q0C0 A0A087WUB0 TRAF7 E3 ubiquitin-protein ligase TRAF7 1 T(0.006)PS(0.919)S(0.037)S(0.012)S(0.012)T(0.012)LAYSPR 83.243 0.009610700000000002 25003000.0 6472.4 6462.5 20395.0 14374.0 16741.0 18661.0 7655.5 18087.0 13045.0 15195.0 True False 8530.488565716718 8551.3767439246 20124.54897414373 11060.296376086228 14416.801120694558 17494.124720013555 8336.824669331392 15292.069747912241 13734.53206810468 14663.027674998048 0.5817685647734313 0.5831931121909814 1.3724688666078242 0.7542982678089845 0.9832076594438043 1.193077248966993 0.5685609312152172 1.0428998762640798 0.93667777027547 1.0 13.839895406671422 -5.097756027881396 24.999974635852272 0.9683779090742709 0.5820196061828117 0.3721680905794914 0.20669818874181087 40.506099921852545 10352.104025732133 0.05026488578731502 0.13298852863903096 7.984430999408877e-06 5.097756027881396 -0.3863583028914592 TPS(ph)SSSTLAYSPR ddPTM_PC-9_Lapatinib_30min_R1 2 TPSSSSTLAYSPR 13 0 A0A087WUB0;H3BR17;Q6Q0C0 A0A087WUB0 TRAF7 E3 ubiquitin-protein ligase TRAF7 1 T(0.158)PS(0.773)S(0.026)S(0.026)S(0.008)T(0.008)LAYSPR;T(0.049)PS(0.932)S(0.019)SSTLAYSPR 152.0 0.00013702 48477000.0 59115.0 91757.0 80132.0 67771.0 92002.0 75637.0 77987.0 91024.0 77738.0 64631.0 True False 58272.00925963673 91544.54230403321 73543.85627846498 72755.10541742844 86590.6232428915 72402.18182845878 82024.78526667827 95253.30733944921 68982.32782256903 75802.38223460582 0.768735856866435 1.207673685250497 0.9702050794505275 0.9597997222864822 1.142320606427598 0.9551438845863244 1.0820871699363528 1.2566004462055484 0.9100284950025852 1.0 16.209955568104746 -6.2379597114817145 24.463722002196544 1.0666186830187996 0.992651560405564 0.07295052238101374 0.13468635602976733 1859.4694360783456 1937399.361300693 0.03827059647967304 0.049370157196330776 5.781496785580591e-07 6.2379597114817145 -0.07396712261323557 TPS(ph)VVESQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSVVESQK 9 0 C9JBF1;A0A087X1C3;A8MZ97 C9JBF1 C2orf74 Uncharacterized protein C2orf74 1 T(0.243)PS(0.757)VVESQK 87.363 0.010948000000000001 4993600.0 16003.0 18670.0 19294.0 17888.0 21398.0 19501.0 16592.0 18378.0 15298.0 17034.0 True False 18711.991826342593 20523.43421426849 19754.04213290247 16885.793353678477 17205.21550682827 18478.333230451513 15020.285644322526 17895.59697310058 15521.704309027398 20122.129358930182 0.9299210581825541 1.0199434586757694 0.9817073422269619 0.8391653314853866 0.8550395040171338 0.9183090368242189 0.7464560721381377 0.889349067083625 0.771374839717889 1.0 14.296495361284345 -5.757788493168069 24.943028709571166 0.8528431287111632 0.9814659409773665 0.3647307036726176 0.07039763022803527 84.44353869565965 576911.1042381632 0.018078900460706777 0.029806386975651755 1.7466725971654892e-06 5.757788493168069 0.1286228122662033 TPS(ph)YSISSTLNPQAPEFILGCTASK ddPTM_PC-9_AZD4547_30min_R2 1 TPSYSISSTLNPQAPEFILGCTASK 25 0 Q14694;Q14694-3;Q14694-2;H3BQC6 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 T(0.377)PS(0.493)Y(0.068)S(0.027)IS(0.024)S(0.005)T(0.005)LNPQAPEFILGCTASK 81.532 3.128e-05 5575400.0 26497.0 24509.0 33784.0 43643.0 39930.0 39319.0 44486.0 57513.0 46300.0 39332.0 True False 34922.494828161995 32431.054950382688 33336.00208592655 33581.780627628454 34386.40874197083 36860.37671433541 48445.167819198796 48625.68736726252 48747.32347667661 37954.99865172908 0.9201026496827728 0.8544607061632778 0.8783033400109972 0.8847788649861695 0.9059783945059979 0.9711600058944067 1.2763843904653076 1.281140537335978 1.284345282790726 1.0 15.212002279818982 -7.138028798009004 3.6030217392429407 1.2339937737569855 0.8890906934408176 0.7790326478874149 0.08073971486861554 0.10102815339683284 2.373331674507007 0.031216541395021145 0.023625325974480093 7.277315471553205e-08 7.138028798009004 -0.3449030803161679 TPSFELPDAS(ph)ERPPTYCELVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSFELPDASERPPTYCELVPR 22 1 Q9BRG2;Q9BRG2-2 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 T(0.156)PS(0.095)FELPDAS(0.724)ERPPT(0.013)Y(0.011)CELVPR 47.485 0.025222 20347000.0 0.0 2517.5 0.0 2351.7 2351.3 3400.8 0.0 3832.0 0.0 0.0 True False 0.0 2767.420762422119 0.0 2219.9418733142707 1890.579643948279 3222.4560612337555 0.0 3731.4140603396127 0.0 0.0 0.0 TPSKPPAQLS(ph)PSVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSKPPAQLSPSVPK 15 1 P18887;F5H8D7;M0QYS5 P18887 XRCC1 DNA repair protein XRCC1 1 TPSKPPAQLS(0.909)PS(0.091)VPK 96.56200000000001 0.0012362999999999999 6973400.0 26994.0 32888.0 30234.0 32182.0 39506.0 29140.0 34181.0 28105.0 28603.0 31238.0 True False 31563.551044197437 36152.90329078001 30954.893223083516 30378.946875451722 31765.08289619392 27611.847101961775 30943.128230990133 27367.273529708993 29021.26476344034 36901.202120128066 0.8553529216052513 0.9797215595602536 0.8388586670513618 0.8232508734148061 0.860814311490069 0.7482641625623536 0.8385398429638677 0.7416363683930309 0.7864585188570442 1.0 15.171380194873013 -5.4394831974061075 6.467402513180014 0.817126951600994 0.9171476900394514 0.17323503004141827 0.07414907432310591 0.3249750897367741 20.770882449234747 0.018280347060048583 0.03832399310113288 3.635103682728704e-06 5.4394831974061075 0.10002073843845738 TPSKPPAQLS(ph)PSVPK ddPTM_PC-9_Lapatinib_30min_R1 1 TPSKPPAQLSPSVPK 15 1 P18887;F5H8D7;M0QYS5 P18887 XRCC1 DNA repair protein XRCC1 1 TPSKPPAQLS(0.894)PS(0.106)VPK 87.352 0.0024487 10493000.0 32337.0 27425.0 24086.0 18655.0 30454.0 29560.0 34331.0 29842.0 30104.0 26300.0 True False 31875.868450120484 27361.49909748696 22105.742054648697 20026.9509312557 28662.755594867664 28295.78770772556 36108.49119712688 31228.56826357708 26713.370510826368 30845.91995745282 1.033390104561262 0.8870378687109323 0.7166504382148482 0.6492576962813812 0.9292235613138952 0.917326756561491 1.1706083412954764 1.012405151366925 0.8660260594488131 1.0 14.91279205380502 -6.718559523636523 2.6614320515033536 1.0116962997867154 0.819060808920838 0.3010337098393766 0.12095544901996934 0.34096869847824585 4.939520025703316 0.0477637769676845 0.045429968020401924 1.911791279902737e-07 6.718559523636523 -0.1926354908658774 TPSNGAEGLT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 TPSNGAEGLTPR 12 0 Q99459 Q99459 CDC5L Cell division cycle 5-like protein 1 TPSNGAEGLT(1)PR;TPSNGAEGLT(1)PR 104.41 0.004679600000000001 39513000.0 33821.0 25868.0 34035.0 33876.0 34457.0 29911.0 23149.1 26899.0 33167.0 24303.0 True False 33338.706337988224 25808.104235325194 31236.77367889932 36367.35404702321 32430.30700506846 28631.776255946545 24347.647128583783 28148.82573962736 29431.383196006438 28503.741168288063 1.1696256340932298 0.9054286622570826 1.095883291055558 1.2758800268465755 1.1377561567654464 1.0044918695725784 0.8541912791318721 0.9875484615663165 1.0325445709825076 1.0 14.798863667623804 -6.882057195930443 4.981258402489154 0.9628634791302387 1.1122478205657556 0.3519595259162206 0.0962725460068368 0.2635177434763932 10.394865314389715 0.03723108079662524 0.0328114340199608 1.3120270956441994e-07 6.882057195930443 0.14938434143551682 TPSNTPSAEADWS(ph)PGLELHPDYK ddPTM_PC-9_AZD4547_30min_R2 2 TPSNTPSAEADWSPGLELHPDYK 23 0 Q9Y3Z3-3;Q9Y3Z3-4;Q9Y3Z3;A0A2R8Y7R5;A0A2R8Y755;A0A2R8Y586;A0A2R8YF51;A0A2R8Y5D2;A0A2R8YCS7 Q9Y3Z3-3 SAMHD1 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 1 T(0.002)PS(0.002)NT(0.007)PS(0.022)AEADWS(0.964)PGLELHPDY(0.002)K;TPSNT(0.001)PS(0.001)AEADWS(0.998)PGLELHPDYK 91.926 9.0899e-06 48626000.0 76126.0 75758.0 99778.0 96824.0 99943.0 96527.0 92736.0 115993.0 87310.0 84908.0 True False 100332.48448083385 100245.29197156515 98454.87852621306 74502.72271588798 86067.63959175549 90491.15143072429 100989.32434656352 98068.94710397442 91925.02835310232 81935.3967639838 1.224531624223938 1.2234674625464168 1.2016159366362 0.9092861651783326 1.050432938521976 1.104420738833858 1.2325481822888447 1.1969057449793472 1.1219208301131904 1.0 16.322199222180686 -14.522666415609223 0.013631816661588227 2.4161219397384193e-06 2.018313903435757 0.12854547578193098 0.0980580869353836 21344.6215576338 22.00014822310048 1999.0426567027291 1322.9097500768971 3.001467080010248e-15 14.522666415609223 2.018311487313817 TPSNTPSAEADWS(ph)PGLELHPDYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPSNTPSAEADWSPGLELHPDYK 23 0 Q9Y3Z3-3;Q9Y3Z3-4;Q9Y3Z3;A0A2R8Y7R5;A0A2R8Y755;A0A2R8Y586;A0A2R8YF51;A0A2R8Y5D2;A0A2R8YCS7 Q9Y3Z3-3 SAMHD1 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 1 TPSNT(0.001)PS(0.002)AEADWS(0.996)PGLELHPDYK;TPSNT(0.001)PS(0.007)AEADWS(0.992)PGLELHPDYK 104.05 1.5903999999999998e-06 34039000.0 92155.0 104047.0 111066.0 103609.0 110194.0 93007.0 99027.0 80702.0 79701.0 79361.0 True False 107755.02135578323 114376.09853733232 113714.23466015034 97804.12363490992 88602.27673424767 88129.54919053408 89646.44566660594 78583.65801083713 80866.47634552195 93748.52107866973 1.14940502651087 1.22003096391625 1.2129709711871213 1.0432604430403432 0.9451058610289591 0.94006335434966 0.956243838677503 0.8382389088025517 0.8625893551713982 1.0 16.51650831111948 -6.023570959145351 2.06236966595719 0.9141893673825244 1.200149876331382 0.8635559360872906 0.047979038861038235 0.10995748723974381 0.9352871072299588 0.016048706960552217 0.024869522492608705 9.471724138616666e-07 6.023570959145351 0.2859605089488576 TPSNTPSAEADWS(ph)PGLELHPDYK ddPTM_PC-9_Lapatinib_30min_R1 3 TPSNTPSAEADWSPGLELHPDYK 23 0 Q9Y3Z3-3;Q9Y3Z3-4;Q9Y3Z3;A0A2R8Y7R5;A0A2R8Y755;A0A2R8Y586;A0A2R8YF51;A0A2R8Y5D2;A0A2R8YCS7 Q9Y3Z3-3 SAMHD1 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 1 TPSNTPSAEADWS(1)PGLELHPDYK;TPSNTPS(0.001)AEADWS(0.998)PGLELHPDYK;TPS(0.003)NT(0.006)PS(0.016)AEADWS(0.974)PGLELHPDYK 113.43 6.5609e-08 46594000.0 238575.0 225205.0 228757.0 215913.0 247134.0 208382.0 197774.0 200884.0 204861.0 183595.0 True False 235172.87675070344 224683.5516590536 209949.48248755626 231791.96228465321 232598.06400413794 199469.98762216725 208013.77000438576 210217.8040030968 181787.39689803362 215329.15112503976 1.0921553144197396 1.0434423322858957 0.9750165334819921 1.0764541682981588 1.0801977474432631 0.9263492034403497 0.9660269820299155 0.9762626328333276 0.8442303141411228 1.0 17.7161841183109 -6.766057432081527 24.99999042127446 0.9425560497821848 1.0498172996031077 0.5612215944226757 0.048967586253363365 93.118090447293 504094.5857581819 0.01698210663962183 0.015473923073985941 1.7137306649156714e-07 6.766057432081527 0.10726124982092289 TPSPKEEDEEPES(ph)PPEK ddPTM_PC-9_Lapatinib_30min_R1 2 TPSPKEEDEEPESPPEK 17 1 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 TPSPKEEDEEPES(1)PPEK;TPSPKEEDEEPES(1)PPEK 118.84 5.0531e-05 35507000.0 101697.0 85946.0 104511.0 108649.0 113745.0 101858.0 107782.0 99765.0 99069.0 91897.0 True False 100246.78213105435 85746.99731750629 95918.50900412658 116639.40990243915 107054.74273127406 97501.77078259512 113362.4245786237 104400.44611003826 87910.80597718101 107781.27400494469 0.9300946111144995 0.7955648892549968 0.8899366786082537 1.0821862237134818 0.9932592068485172 0.9046262598280479 1.0517821915282146 0.9686325112955028 0.8156408132005186 1.0 16.71774701943867 -5.5397471974387535 24.93822713896626 0.9745694315558469 0.8578099847105329 0.27765074719686256 0.0760423072488804 263.5767493833404 389668.8688166711 0.02054675038753006 0.03559810926597852 2.885710784867141e-06 5.5397471974387535 -0.11675944684531392 TPSPKEEDEEPES(ph)PPEKK ddPTM_PC-9_AZD4547_30min_R2 5 TPSPKEEDEEPESPPEKK 18 2 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 TPSPKEEDEEPES(1)PPEKK;TPSPKEEDEEPES(1)PPEKK;TPSPKEEDEEPES(1)PPEKK;TPSPKEEDEEPES(1)PPEKK;TPSPKEEDEEPES(1)PPEKK 122.65 0.00015599 104832600.0 208821.0 182971.0 175040.0 230419.0 240562.0 218746.0 208985.0 183388.0 197962.0 230207.0 True False 275221.734253373 242112.79755707973 172718.85523089577 177299.4594880625 207164.11870237833 205067.77803998115 227584.2601424097 155049.5984370065 208425.86717256688 222147.52299955784 1.2389142608352235 1.0898739463215246 0.7774962011673637 0.7981158515479617 0.9325520082562013 0.9231153031600056 1.0244735438389863 0.6979578090425753 0.9382317856093391 1.0 17.761158529463877 -5.0436027921253475 4.04845464968342 0.8811401285337236 1.2173692703917984 0.5834085322544715 0.09745304536602609 0.13598310925303284 4.69764841799137 0.025104303308160866 0.08798144380595907 9.04476334054488e-06 5.0436027921253475 0.33622914185807484 TPSPKEEDEEPES(ph)PPEKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TPSPKEEDEEPESPPEKK 18 2 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 TPSPKEEDEEPES(1)PPEKK;TPSPKEEDEEPES(1)PPEKK;TPSPKEEDEEPES(1)PPEKK;TPSPKEEDEEPES(1)PPEKK;TPSPKEEDEEPES(1)PPEKK 126.26 0.00012323 47663000.0 125349.0 107589.90000000001 79182.1 145899.0 134727.5 113834.3 132268.3 136830.2 94134.5 105196.5 True False 146568.1099443991 118270.71423512179 81070.10156378648 137724.75204094028 108328.6135244512 107864.62891416789 119738.88908443498 133238.55223358105 95511.03897752253 124267.79271496437 1.1794537163831778 0.9517406855885966 0.6523822447682697 1.1082900004254717 0.8717352353149685 0.8680014874133899 0.9635552903002195 1.0721889342574316 0.7685904520457542 1.0 16.9230929066982 -4.780360615496568 4.981677971313291 0.914310861673977 1.1923931583244092 0.2740190971817712 0.1290070982298447 0.2069018636757765 12.908281806328992 0.031028948552162424 0.19247628001032654 1.6582094449550264e-05 4.780360615496568 0.27808229665043216 TPSPKEEDEEPES(ph)PPEKK ddPTM_PC-9_Lapatinib_30min_R1 4 TPSPKEEDEEPESPPEKK 18 2 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 TPSPKEEDEEPES(1)PPEKK;TPSPKEEDEEPES(1)PPEKK;TPSPKEEDEEPES(1)PPEKK;TPSPKEEDEEPES(1)PPEKK 99.846 0.0017545000000000002 225201000.0 165813.0 151792.0 137811.0 163247.0 154676.0 160019.0 142148.0 136488.0 140716.0 141166.0 True False 163448.47621361972 151440.53495007282 126480.71154584359 175252.72895602815 145578.2617847164 153175.3603925081 149507.7279044942 142829.73075394073 124867.0822748285 165566.35500812888 0.9872082779475022 0.9146818201236445 0.7639276200749464 1.0585044826735703 0.8792744261209886 0.9251599480159334 0.9030079082018431 0.8626736437299001 0.7541815018437643 1.0 17.337050004795316 -7.705369147236738 3.8883372950848094 0.8556022798766588 0.9178372240219086 0.04633462231738561 0.09000862254848435 0.5890446526383738 17.99124365177342 0.04632308380338053 0.024034276298668226 1.9707469030691805e-08 7.705369147236738 0.06223494414524977 TPSS(ph)EEISPTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSSEEISPTK 11 0 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 T(0.076)PS(0.243)S(0.681)EEISPTK 145.81 0.00021334 8691000.0 30365.0 41286.0 33198.0 32227.0 44498.0 19360.0 29820.0 23292.0 22653.0 20599.0 True False 35505.19476391255 45384.60123033149 33989.56622411611 30421.42567134369 35778.93633156576 18344.727518667813 26995.233721895955 22680.609679913956 22984.257269734444 24333.43563840571 1.4591114584688707 1.8651127569795576 1.396825615963166 1.2501903193369557 1.470361064637149 0.7538897421338293 1.1093885024311612 0.9320759311158231 0.9445545467265689 1.0 14.570652408356988 -6.157635475890558 0.8950208286279151 0.9469163536294988 1.665322608842089 0.6791071176048268 0.17956729108585856 0.3461537838090042 0.5820823147091243 0.08401932928602181 0.15577963712723894 6.956079295995752e-07 6.157635475890558 0.7184062552125902 TPSS(ph)EEISPTK ddPTM_PC-9_Lapatinib_30min_R1 1 TPSSEEISPTK 11 0 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 T(0.01)PS(0.355)S(0.635)EEISPTK 111.12 0.0018512999999999997 8367700.0 19352.0 29893.0 33221.0 27354.0 27600.0 34294.0 36211.0 35128.0 34178.0 23410.0 True False 19076.03693127783 29823.78459512044 30489.697616768455 29365.704410269005 25976.622263687772 32827.32556321856 38085.82839821626 36760.17512106883 30328.51372970447 27456.387308135767 0.6947759265336885 1.086223917969105 1.1104774009264455 1.0695399974040822 0.9461048888974 1.1956170779063602 1.3871391006686018 1.3388569555243781 1.1046068584819841 1.0 14.744854188737369 -6.85216144566755 5.424610529967714 1.2425578054049118 0.9997928163162508 0.3401596123066153 0.151389587274141 0.23135987756229406 10.856477691136956 0.05383737527499429 0.04764665416363879 1.4055249338069614e-07 6.85216144566755 -0.24276498908866095 TPSS(ph)EEISPTKFPGLYR ddPTM_PC-9_AZD4547_30min_R2 2 TPSSEEISPTKFPGLYR 17 1 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 T(0.153)PS(0.222)S(0.621)EEIS(0.004)PT(0.001)KFPGLYR;T(0.042)PS(0.061)S(0.897)EEISPTKFPGLYR 66.67399999999999 0.0093486 47987000.0 49044.0 41987.0 53035.0 86968.0 61291.0 50377.0 49220.0 57719.0 43955.0 60406.0 True False 64638.97182142798 55558.47664946416 52331.721247546586 66918.87124220595 52781.80260967024 47226.918226253816 53600.484648225596 48799.854800671565 46278.37156408897 58291.20432615542 1.1088975183932561 0.9531193821043584 0.8977635966266218 1.1480097557733813 0.9054848535010779 0.8101894406230851 0.9195295459725974 0.8371735558528328 0.7939168884751235 1.0 15.8309905883207 -6.5052756143465 23.86848785623853 0.86415585555123 1.0142342941496254 0.4183577884724342 0.08616917321085475 408.08804865817206 553336.6890751066 0.02630198113778659 0.029161825480922617 3.1240961068676774e-07 6.5052756143465 0.15007843859839542 TPSS(ph)EEISPTKFPGLYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSSEEISPTKFPGLYR 17 1 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 T(0.39)PS(0.181)S(0.429)EEISPTKFPGLYR 142.95 0.00054872 11384000.0 21659.0 10402.0 16262.0 24723.0 26752.0 25783.0 24778.0 19593.0 21734.0 16833.0 True False 25325.44091525052 11434.641815576915 16649.747753978427 23337.850463047445 21510.137640838857 24430.894091622544 22430.848462814818 19078.704510499494 22051.81863331162 19884.689650045315 1.2736150958832193 0.5750475374178574 0.8373149416460962 1.1736592762459463 1.0817436942391423 1.2286283830216516 1.1280461932059223 0.9594670495878731 1.1089848029517206 1.0 14.279370425030034 -5.75463278686647 24.958252621389605 1.1016447337655055 0.8632979643329328 0.2125949944664477 0.17467904082382923 201.4232379667869 738565.0296797273 0.04610162868155188 0.07760087276050065 1.7594106363692978e-06 5.75463278686647 -0.2383467694325727 TPSS(ph)EEISPTKFPGLYR ddPTM_PC-9_Lapatinib_30min_R1 1 TPSSEEISPTKFPGLYR 17 1 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 T(0.017)PS(0.006)S(0.977)EEISPTKFPGLYR 101.61 0.00049295 32072000.0 44554.0 28920.0 29388.0 29616.0 27582.0 26614.0 20987.0 22965.0 32287.0 21274.0 True False 43918.65178979708 28853.037516839515 26971.832080960587 31794.059436079806 25959.68098829842 25475.78126026415 22073.60416982033 24032.037737854287 28650.498062817245 24951.182554176838 1.7601831774680787 1.1563795605354787 1.0809841185842108 1.2742506038359078 1.0404188631914266 1.021025003722699 0.8846716632324587 0.9631622744001492 1.1482621314884789 1.0 14.606820572852131 -2.1997062505566967 1.0519273886941949 1.033484566166071 199.99999998844484 0.8143490728244985 0.10069017002589713 193.61291774387377 1.0367428480607912 0.0335215895320181 91933.83808235064 0.006313842577201945 2.1997062505566967 198.96651542227877 TPSS(ph)PCPASK ddPTM_PC-9_AZD4547_30min_R2 3 TPSSPCPASK 10 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 TPS(0.002)S(0.997)PCPAS(0.001)K;T(0.001)PS(0.024)S(0.975)PCPASK;T(0.011)PS(0.105)S(0.884)PCPASK 91.961 0.007737000000000001 194820000.0 166940.0 157833.0 221531.0 278088.0 260152.0 210032.0 195259.0 247299.0 192462.0 223901.0 True False 220023.44743228887 208849.43065746265 218593.35419421617 213979.10801677106 224034.38535039278 196898.66583751573 212636.67273319542 209084.62191568277 202635.14840103948 216062.29414016035 1.0183333853224705 0.966616741197709 1.0117144921751775 0.9903584004248427 1.0368971885722036 0.9113050781076447 0.9841452141355922 0.9677052756833585 0.9378552107272793 1.0 17.721087798354112 -6.749822797644885 24.999999736499678 0.9596801690815293 1.002247227573599 0.37963017502407037 0.028398953236832548 243.41621311759542 523854.2576885221 0.00896195380623267 0.008892243565888323 1.7790051378770894e-07 6.749822797644885 0.042567058492069654 TPSS(ph)PCPASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSSPCPASK 10 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 T(0.165)PS(0.173)S(0.661)PCPASK 105.36 0.0024718000000000006 58244000.0 109710.0 115730.0 120350.0 125030.0 150740.0 125950.0 132790.0 138350.0 111210.0 95707.0 True False 128281.7361287285 127218.90956707532 123219.60042991636 118024.9744527294 121203.57909614385 119344.96027769684 120211.16988365387 134718.45909394187 112836.23586135 113057.92148380501 1.134655002012435 1.1252542758385913 1.0898802915598176 1.0439337014490921 1.0720485349936817 1.055609007413005 1.0632706519451938 1.1915879694749176 0.9980391854056262 1.0 16.786702553523398 -8.482424040796056 0.010816671083462036 7.552368106119666e-08 2.120042685450877 0.2685428116331319 0.04903725854601081 1986.54653418077 14.760311122945579 1464.7133904165682 1425.7982055967464 3.2928804160889103e-09 8.482424040796056 2.120042609927196 TPSS(ph)PCPASK ddPTM_PC-9_Lapatinib_30min_R1 1 TPSSPCPASK 10 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 T(0.002)PS(0.056)S(0.942)PCPASK 98.182 0.004857899999999999 32571000.0 45604.0 40078.0 42737.0 41387.0 46787.0 39917.0 39735.0 35138.0 51681.0 34727.0 True False 44953.67859725063 39985.201853385 39223.32882959074 44430.73804298471 44035.08064678116 38209.84296107178 41792.28387515182 36770.639757575635 45860.14155494343 40729.51567918113 1.1037125742260834 0.9817254437381737 0.9630197701967697 1.0908732230689269 1.0811589559187826 0.9381364429187828 1.0260933177880611 0.9028008102824293 1.1259682515298068 1.0 15.313787038688275 -6.7504020156968805 24.99926166970174 0.9942431541212904 1.0387271170483994 0.09389820843211505 0.06901618034196631 570.1412527854499 1291348.2372303607 0.022447348334965388 0.02224557293065143 1.7766340622686638e-07 6.7504020156968805 0.04448396292710899 TPSS(ph)PLQSCTPSLSPR ddPTM_PC-9_AZD4547_30min_R2 1 TPSSPLQSCTPSLSPR 16 0 R4GNJ5;A0A590TQL1;Q96AP0-2;Q96AP0 R4GNJ5 ACD Adrenocortical dysplasia protein homolog 1 TPS(0.003)S(0.993)PLQS(0.001)CT(0.001)PS(0.001)LSPR 144.4 2.9346e-05 15438000.0 20759.0 17198.0 20749.0 43076.0 34407.0 20486.0 20760.0 28269.0 21968.0 21257.0 True False 27359.93018597632 22756.917174779934 20473.85470284425 33145.49371756579 29630.181958051347 19205.007181512123 22607.599782551064 23900.675606995712 23129.183631439122 20512.79890012724 1.3337980018809918 1.1094008811561435 0.9981014683821258 1.615844521215493 1.4444728923787944 0.9362450865441379 1.102121650615452 1.1651591634746372 1.1275488900393624 1.0 14.324236735523149 -6.763325625244408 24.999999652419596 1.07878158760753 1.2904555569883072 0.3213723935316044 0.16930357857389539 76.72420193695866 1016878.4689234904 0.0635294867612745 0.058892079725426996 1.7245443785283455e-07 6.763325625244408 0.2116739693807772 TPSS(ph)PLQSCTPSLSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPSSPLQSCTPSLSPR 16 0 R4GNJ5;A0A590TQL1;Q96AP0-2;Q96AP0 R4GNJ5 ACD Adrenocortical dysplasia protein homolog 1 TPS(0.132)S(0.866)PLQS(0.002)CT(0.001)PSLSPR;T(0.004)PS(0.312)S(0.684)PLQSCTPSLSPR 135.57 8.0421e-06 20066500.0 21803.1 22340.0 21778.2 23719.0 33382.0 25147.0 26908.0 34350.0 33117.0 23859.0 True False 25493.93419914579 24557.767560083477 22297.474882283437 22390.101328035544 26841.036734692058 23828.247051236558 24359.07944295026 33448.34889683344 33601.27347379135 28184.447832259924 0.9045390688820034 0.8713233520216299 0.7911269014382373 0.7944133396293763 0.9523350215848402 0.8454395556390053 0.8642737863066756 1.1867661589789407 1.1921920086485187 1.0 14.78261168314837 -7.755210769656081 24.999401863962607 1.1421093344614803 0.8586534719397271 0.7678461949488206 0.06680767762061449 61.18664830929829 245584.04067240516 0.032082842338900575 0.017927166696944358 1.757070674129203e-08 7.755210769656081 -0.28345586252175325 TPSS(ph)PLQSCTPSLSPR ddPTM_PC-9_Lapatinib_30min_R1 1 TPSSPLQSCTPSLSPR 16 0 R4GNJ5;A0A590TQL1;Q96AP0-2;Q96AP0 R4GNJ5 ACD Adrenocortical dysplasia protein homolog 1 T(0.001)PS(0.123)S(0.875)PLQSCTPSLSPR 125.39 3.1936999999999996e-05 13245000.0 22487.0 16617.0 24227.0 22125.0 23984.0 30744.0 28563.0 27652.0 28306.0 27648.0 True False 22166.331256389236 16578.524357445433 22235.149578924447 23752.146306836356 22573.308274358245 29429.150787764378 30041.85238016763 28936.81286858902 25117.880204605743 32426.91996135571 0.6835780667052445 0.5112580651262173 0.6857003256992292 0.7324823429157815 0.696128657956403 0.9075530708077154 0.926447914756306 0.8923700710111854 0.7745996300154191 1.0 14.984904376901461 -6.372223856284207 1.0686120757817987 0.9011033513857526 0.6081411160167756 0.7072531618793545 0.07622372390168741 0.28001211009644905 0.6746819623183418 0.03493122534587922 0.04714530260005834 4.244007509788138e-07 6.372223856284207 -0.29296223536897703 TPSS(ph)SPPITPPASETK ddPTM_PC-9_Lapatinib_30min_R1 1 TPSSSPPITPPASETK 16 0 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 TPSS(0.603)S(0.396)PPITPPASETK 153.2 1.0624e-10 0.0 28144.0 21141.0 27236.0 29498.0 38398.0 31450.0 33426.0 32332.0 41479.0 28986.0 True False 27742.661399022498 21092.04931339917 24996.761214000348 31667.38132244337 36139.50513337258 30104.956813530756 35156.63472532591 33834.26275376899 36807.198226766086 33996.191478582776 0.8160520397262755 0.6204238885607797 0.7352812220082956 0.9314979103583844 1.0630456989907258 0.8855391002399944 1.0341345073160386 0.9952368569015798 1.0826859311565595 1.0 15.053085512891226 -5.820663874947063 3.357459227715141 1.0044465825459243 0.7081856575973959 0.7862221631451242 0.06666303817956934 0.09783773124490515 2.2280131004605717 0.018595385163316245 0.03049203253015915 1.5112493429620557e-06 5.820663874947063 -0.2962609249485284 TPSS(ph)SSTLAYSPR ddPTM_PC-9_AZD4547_30min_R2 1 TPSSSSTLAYSPR 13 0 A0A087WUB0;H3BR17;Q6Q0C0 A0A087WUB0 TRAF7 E3 ubiquitin-protein ligase TRAF7 1 T(0.038)PS(0.271)S(0.674)S(0.016)S(0.001)T(0.001)LAYSPR 135.04 4.9217e-05 23110000.0 42560.0 46421.0 54982.0 49604.0 59022.0 51822.0 54127.0 59775.0 60193.0 54335.0 True False 56093.19469700628 61425.68043786832 54252.90275539941 38168.5641741604 50827.81409387935 48581.56214782396 58944.198142106994 50538.147242851504 63374.67909355498 52432.748188286874 1.0698122191797896 1.1715136543537195 1.0347140790823386 0.7279527679361083 0.969390616554292 0.9265499869159397 1.1241866997022052 0.96386607586099 1.2086850543476273 1.0 15.678180544204146 -9.432742901715127 11.296067585319122 0.9999918189194944 1.0149466865353116 3.3607892517828475e-06 0.1312425989206022 0.0 0.0 0.1328864546775239 0.0322296993440756 3.6919609453636894e-10 9.432742901715127 0.014954867615817213 TPSSEEIS(ph)PTKFPGLYR ddPTM_PC-9_AZD4547_30min_R2 2 TPSSEEISPTKFPGLYR 17 1 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 TPSSEEIS(0.918)PT(0.08)KFPGLY(0.001)R;T(0.001)PS(0.004)S(0.012)EEIS(0.971)PT(0.011)KFPGLYR 62.556000000000004 0.013415999999999999 17942100.0 47828.0 33921.0 41547.0 51282.0 42443.0 49509.0 41146.0 40896.0 36105.0 44677.0 True False 63036.309115799246 44885.29988869111 40996.05963367247 39459.727199001936 36550.522069508326 46413.19440346988 44807.91428963611 34576.4628965898 38013.436590181635 43112.871828620446 1.4621227128263963 1.0411113429677408 0.9509006914834486 0.9152655697783192 0.847786763424196 1.0765507477202787 1.039316389493924 0.8019986011146732 0.8817189618286213 1.0 15.395831045868075 -4.704720975370886 2.335346062597433 0.9364790531408362 1.662005810867975 0.792461755071135 0.08002630193376921 0.36026193726897193 1.9704887785089467 0.022343571937690807 0.5815917542357363 1.9736903814074643e-05 4.704720975370886 0.7255267577271387 TPSSEEIS(ph)PTKFPGLYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSSEEISPTKFPGLYR 17 1 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 T(0.002)PS(0.002)S(0.003)EEIS(0.891)PT(0.08)KFPGLY(0.022)R 48.391000000000005 0.044645 5091100.0 12476.0 11020.0 10673.0 11003.0 12071.0 14703.0 13867.0 9953.1 14263.0 11652.0 True False 14587.94038776792 12113.992771357194 10927.484797577908 10386.537582207298 9705.774202398545 13931.948796847773 12553.417371614052 9691.841671181166 14471.56939205502 13764.415362818743 1.0598300039080288 0.8800949733092356 0.7938938566977483 0.7545934431958535 0.7051352307063007 1.0121714892796378 0.912019656535801 0.7041230169035253 1.0513755223593793 1.0 13.748655712979145 -6.775984497086556 24.992906418209344 0.9159506857248734 0.8338457834577245 0.1203999208539378 0.1253795965958721 651.7019756245859 1119814.2848039703 0.04567679168637828 0.04045324373035168 1.675002667156599e-07 6.775984497086556 -0.08210490226714884 TPSSEEIS(ph)PTKFPGLYR ddPTM_PC-9_Lapatinib_30min_R1 1 TPSSEEISPTKFPGLYR 17 1 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 TPS(0.001)S(0.001)EEIS(0.918)PT(0.081)KFPGLYR 76.329 0.0039606 5751200.0 20330.0 18807.0 13566.0 13338.0 15500.0 11691.0 15677.0 16391.0 12434.0 10346.0 True False 20040.09047193461 18763.45354699863 12450.655846274374 14318.921014263658 14588.320474172478 11191.003183052082 16488.67835184987 17152.585698287392 11033.55198417535 12134.292314821547 1.6515252766291488 1.546316263048965 1.0260718567877587 1.1800375862689312 1.2022390837208887 0.9222625343698638 1.3588496077113303 1.4135629217812895 0.9092868127709692 1.0 13.566802350941748 -5.16623004494556 5.060600736345241 1.147484543366271 1.6221263244473068 0.5719922973520215 0.1632339072254488 0.15994390593812158 6.474475115732297 0.04183539313648598 0.1180213076354923 6.819773563659149e-06 5.16623004494556 0.4746417810810357 TPSSGMS(ph)STMK ddPTM_PC-9_AZD4547_30min_R2 1 TPSSGMSSTMK 11 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5;A0A0A0MSW0 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 T(0.008)PS(0.006)S(0.01)GMS(0.903)S(0.068)T(0.006)MK 64.22399999999999 0.028525 2274500.0 12606.0 14498.0 16150.0 17823.0 16502.0 14620.0 14569.0 17647.0 14922.0 16306.0 True False 16614.445778911206 19184.194976157665 15935.840447777458 13714.182712605048 14210.982145254253 13705.809088826876 15865.612776107246 14920.061637718103 15710.746456133224 15735.13190316012 1.0558822055742978 1.21919505309675 1.0127554408728554 0.8715645217979267 0.9031371476714619 0.8710323607820732 1.0082923278781617 0.9482006080115335 0.9984502546799752 1.0 13.941701651940942 -5.482357412664441 5.7778499843517706 0.9388069001094317 1.1349061243226233 0.622052472928434 0.06003235283529447 0.11749475288186695 10.344618155173379 0.015863862071716025 0.03249100950556436 3.2933856384886464e-06 5.482357412664441 0.1960992242131916 TPSSGTMSSADDLDEREPPS(ph)PSETGPNSLGTFKK ddPTM_PC-9_AZD4547_30min_R2 1 TPSSGTMSSADDLDEREPPSPSETGPNSLGTFKK 34 2 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 T(0.004)PS(0.004)S(0.01)GT(0.025)MS(0.141)S(0.141)ADDLDEREPPS(0.431)PS(0.183)ET(0.062)GPNSLGTFKK 54.824 0.0026287 12842000.0 6745.7 4142.1 7970.5 14470.0 10616.0 10590.0 5371.4 7422.9 7847.1 9043.9 True False 8890.692280723568 5480.952821819742 7864.805962167818 11134.165059271441 9142.151645498676 9927.805625901266 5849.444194219403 6275.861366272895 8261.88168582784 8727.275813748918 1.0187247968853241 0.6280256220601014 0.9011753644565274 1.2757892951808305 1.0475378389091548 1.1375606589929286 0.6702485768817126 0.7191088605663094 0.9466736083683871 1.0 13.091315676967552 -7.261951493507587 24.999990009872093 0.8106001715779847 0.9944985816391871 0.16481998026718137 0.18123478817928462 88.08620939258597 4299969.8278022595 0.07855241878438171 0.05665547752983728 5.4707706269744784e-08 7.261951493507587 0.18389841006120244 TPSSGTMSSADDLDEREPPS(ph)PSETGPNSLGTFKK ddPTM_PC-9_Lapatinib_30min_R1 1 TPSSGTMSSADDLDEREPPSPSETGPNSLGTFKK 34 2 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 T(0.001)PS(0.001)S(0.001)GT(0.007)MS(0.021)S(0.021)ADDLDEREPPS(0.728)PS(0.199)ET(0.018)GPNSLGTFKK 49.525 0.018308 7510100.0 31324.0 12437.0 14638.0 11488.0 15670.0 16910.0 12142.0 11834.0 17058.0 7113.2 True False 30877.314015881908 12408.202890626999 13434.52014431404 12332.865842844574 14748.321408405334 16186.7987191353 12770.653348737718 12383.85084214098 15136.7484112967 8342.707142256784 3.701114457138824 1.487311334204458 1.6103310250777747 1.4782810462538198 1.767810035390475 1.9402333610809948 1.5307565195538113 1.484392371801634 1.8143689036652508 1.0 13.026299887393815 -4.759600183031322 24.99999766052076 1.5985079598654046 3.7011170938667393 0.8729306186785232 0.24388916231643434 15.02859430971354 204225.4412873389 0.0575589801862767 0.3617113460043355 1.7394014067177873e-05 4.759600183031322 2.1026091340013346 TPSSPLQSCTPS(ph)LSPR ddPTM_PC-9_AZD4547_30min_R2 2 TPSSPLQSCTPSLSPR 16 0 R4GNJ5;A0A590TQL1;Q96AP0-2;Q96AP0 R4GNJ5 ACD Adrenocortical dysplasia protein homolog 1 T(0.001)PSSPLQS(0.018)CT(0.261)PS(0.522)LS(0.198)PR;TPS(0.002)S(0.002)PLQS(0.277)CT(0.277)PS(0.443)LSPR 90.42200000000001 0.0035155 14304600.0 6672.7 9093.2 17185.4 17360.8 15782.099999999999 16999.3 14764.9 17998.5 11289.2 18303.1 True False 8794.479799217897 12032.399072782235 16957.51036725913 13358.535781686222 13591.027833875722 15936.331083700044 16078.947496598666 15217.245389384565 11885.924064641413 17662.314040030065 0.4979234192805082 0.6812470351003765 0.9600956210396009 0.756329875655607 0.7694930462153976 0.9022787754527388 0.9103533919823393 0.8615657809557701 0.6729539536950268 1.0 14.1083867505863 -4.962869109360938 3.4997439968410977 0.8462721059468776 0.505324502565005 0.5858479681663631 0.09466385988737434 0.1674107232558656 4.088072609037906 0.02379956800075263 0.11892140484951065 1.0892583319879761e-05 4.962869109360938 -0.3409476033818726 TPSSPLQSCTPS(ph)LSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSSPLQSCTPSLSPR 16 0 R4GNJ5;A0A590TQL1;Q96AP0-2;Q96AP0 R4GNJ5 ACD Adrenocortical dysplasia protein homolog 1 TPSSPLQS(0.004)CT(0.014)PS(0.974)LS(0.008)PR 88.95100000000001 0.0038734000000000004 5065800.0 4629.0 5757.1 9223.8 7587.3 9648.7 7981.4 12582.0 7255.8 8011.5 5663.7 True False 5412.598273082533 6328.626840651588 9443.730373456301 7162.2081793584875 7758.106498772494 7562.841333548314 11390.141874208408 7065.342938155578 8128.65303123107 6690.48397617547 0.8089995121962127 0.9459146547824582 1.4115167762280016 1.0705067383559705 1.1595732874331337 1.1303877806866096 1.7024391530968792 1.0560286764477673 1.2149574022113885 1.0 12.7078948609658 -5.075619322899994 5.345771369255193 1.226279173409213 0.8379137780833501 0.33656928742128656 0.1951191543406403 0.20924390420094288 10.52820713281067 0.049214915200533095 0.14229288441701088 8.401961305476502e-06 5.075619322899994 -0.388365395325863 TPSSPLQSCTPS(ph)LSPR ddPTM_PC-9_Lapatinib_30min_R1 2 TPSSPLQSCTPSLSPR 16 0 R4GNJ5;A0A590TQL1;Q96AP0-2;Q96AP0 R4GNJ5 ACD Adrenocortical dysplasia protein homolog 1 TPSSPLQSCTPS(0.947)LS(0.052)PR;TPSSPLQS(0.001)CT(0.011)PS(0.931)LS(0.056)PR 115.91 0.00016836 16697600.0 16493.1 18560.2 17562.7 11581.1 14195.7 18225.0 12365.8 14556.0 17237.2 13401.599999999999 True False 16257.905369535878 18517.2249972353 16118.762599982518 12432.81272741707 13360.736835820015 17445.55923455002 13006.040617675902 15232.324899290525 15295.76502023704 15718.048703490473 1.034346290447969 1.1780867553313548 1.025493870393916 0.7909895790471843 0.8500251582025589 1.1099061698845558 0.8274589844468213 0.9690977033241992 0.9731338354257895 1.0 13.940134506781439 -5.526351494143975 24.99680759350122 0.9282617476459128 1.1051099897642225 0.3648518475130137 0.093424339034781 96.09624046657073 691697.138939685 0.025130667317293146 0.043797281956650135 2.976106756784828e-06 5.526351494143975 0.17684824211830963 TPSSPLQSCTPSLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 TPSSPLQSCTPSLSPR 16 0 R4GNJ5;A0A590TQL1;Q96AP0-2;Q96AP0 R4GNJ5 ACD Adrenocortical dysplasia protein homolog 1 TPSSPLQSCT(0.001)PS(0.242)LS(0.757)PR 136.33 1.0064e-05 8573900.0 6760.8 8055.5 10139.0 13274.0 10231.0 10029.0 7708.3 12404.0 7149.4 8983.5 True False 8910.593766624059 10659.28284111174 10004.55023529508 10213.884381255639 8810.602249914933 9401.885044585815 8394.323767044232 10487.246815563854 7527.302688210623 8668.990399364588 1.0278698390619028 1.2295875701849937 1.154061750492697 1.178209215920263 1.016335449000004 1.0845420990747603 0.9683161914286481 1.209742580443109 0.8683021137919766 1.0 13.081648269961308 -6.263070164849092 24.972617044881943 1.0352158060698946 1.1537738914602265 0.28452379531682037 0.09435133989322493 189.41153760875665 2900505.3084785775 0.02684971979886852 0.032027866471700944 5.456696952811907e-07 6.263070164849092 0.11855808539033186 TPSSPLQSCTPSLS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPSSPLQSCTPSLSPR 16 0 R4GNJ5;A0A590TQL1;Q96AP0-2;Q96AP0 R4GNJ5 ACD Adrenocortical dysplasia protein homolog 1 TPSSPLQSCT(0.005)PS(0.328)LS(0.667)PR 136.36 1.0156e-05 5552500.0 10462.0 14918.0 12622.0 13994.0 16366.0 13266.0 15222.0 13052.0 14831.0 13546.0 True False 12233.009966081114 16398.960450372655 12922.956349201564 13209.96154916013 13159.199784314023 12570.307606541703 13780.061962263582 12709.398829737122 15047.875317504595 16001.782569922998 0.7644779519173269 1.024820852221564 0.807594797187883 0.8255306239437109 0.8223583670639356 0.7855567060490432 0.8611579305023573 0.7942489390916827 0.9403874381963313 1.0 13.965945007258398 -8.464030048436305 4.34692074678213 0.99928520953114 0.8398710604001252 0.3926081547697906 0.06861051139767721 0.19342278325894613 7.317189433610313 0.0646311742909741 0.016898511392244183 3.4353417826332537e-09 8.464030048436305 -0.15941414913101482 TPSSS(ph)PPITPPASETK ddPTM_PC-9_AZD4547_30min_R2 2 TPSSSPPITPPASETK 16 0 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 T(0.008)PS(0.027)S(0.146)S(0.819)PPITPPASETK;T(0.001)PS(0.029)S(0.151)S(0.817)PPIT(0.003)PPASETK 104.55 0.001231 22955000.0 107449.0 85124.0 109835.0 141010.0 135122.0 123781.0 111507.0 137416.0 101257.0 129656.0 True False 141615.5469219605 112638.66830945275 108378.51613508585 108502.32308278272 116362.64267549645 116040.95450233111 121430.90698231793 116181.51470554042 106609.23829973747 125116.78290421485 1.1318669137327206 0.9002682589408096 0.8662188526542979 0.8672083837533483 0.9300322464699218 0.9274611431718806 0.9705405155380418 0.9285845752163004 0.8520778413984147 1.0 16.93291579702364 -4.759409445785934 24.998985618780125 0.9130381507224256 1.1318671921987404 0.6795226545848192 0.04447364114993025 31.290856917367794 385254.3661914396 0.011214427569378453 0.07127579506561335 1.740165500004623e-05 4.759409445785934 0.21882904147631488 TPSSS(ph)PPITPPASETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TPSSSPPITPPASETK 16 0 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 TPS(0.018)S(0.281)S(0.701)PPITPPASETK;T(0.008)PS(0.038)S(0.192)S(0.76)PPIT(0.002)PPASETK;T(0.009)PS(0.009)S(0.203)S(0.555)PPIT(0.221)PPAS(0.003)ETK;T(0.001)PS(0.001)S(0.035)S(0.962)PPIT(0.001)PPASETK 123.36 4.2634e-05 14697500.0 117353.0 106063.0 124201.0 151486.0 180287.0 200821.0 188106.0 201765.0 188371.0 161780.0 True False 137218.54507259766 116592.23369405232 127162.42287491538 142998.73054423858 144961.0565510584 190289.5932348342 170287.237910495 196468.88253768854 191125.56951208026 191109.43335022434 0.7180103183139733 0.6100809973120851 0.6653906123089142 0.7482557403756266 0.7585238154382724 0.995710101270157 0.891045695261045 1.0280438756659518 1.0000844341463058 1.0 17.544039467360733 -6.580235828521401 1.2173949540018743 0.9965475136284823 0.6584038058333387 0.8894192343830748 0.050069046529807634 0.13159618978937798 0.41010267954273244 0.02217877399960628 0.02373856488234742 2.6288401040135986e-07 6.580235828521401 -0.3381437077951436 TPSSS(ph)PPITPPASETK ddPTM_PC-9_Lapatinib_30min_R1 1 TPSSSPPITPPASETK 16 0 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 T(0.001)PS(0.022)S(0.117)S(0.825)PPIT(0.035)PPASETK 117.2 0.00014655 8990100.0 69166.0 58966.0 65582.0 72575.0 77060.0 80434.0 74538.0 67064.0 90269.0 81676.0 True False 68179.6801565092 58829.46784986026 60190.10111384087 77912.40760310269 72527.48230578912 76994.02532081182 78397.2129227649 70180.03826916864 80101.95464528915 95793.58777357078 0.7117353232208703 0.6141274089129708 0.6283312120651898 0.8133363559496886 0.7571225171900209 0.8037492603659876 0.8183972930220963 0.7326172857733922 0.836193282943194 1.0 16.547641467693772 -14.522878745278588 0.039208024038435964 2.2784007680180136 4.1857428572742945e-13 0.7354021505994722 0.05442363908514786 468.1862662844196 1.3670255619781142 70.81923394905427 21.7264265850543 3.0000000000120876e-15 14.522878745278588 -2.278400768017595 TPST(ph)PVACSTPAQLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPSTPVACSTPAQLK 15 0 Q6PL18;A0A0B4J211 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 T(0.025)PS(0.055)T(0.891)PVACS(0.025)T(0.004)PAQLK;T(0.01)PS(0.019)T(0.968)PVACS(0.002)TPAQLK 145.69 0.00027608 11557000.0 40666.0 53516.0 53048.0 56791.0 66459.0 54336.0 65230.0 58604.0 53269.0 40648.0 True False 47549.950609888605 58828.714805077296 54312.86550566033 53609.18438890618 53436.836029923375 51486.52450693877 59050.94217569663 57065.70709607068 54047.95834995296 48017.16063060906 0.9902699365271792 1.225160214233415 1.131113643380196 1.1164588593922902 1.1128695518047662 1.072252582842604 1.2297882965210976 1.1884440134865768 1.1255967166767353 1.0 15.551262475636511 TPST(ph)PVACSTPAQLK ddPTM_PC-9_Lapatinib_30min_R1 2 TPSTPVACSTPAQLK 15 0 Q6PL18;A0A0B4J211 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 T(0.012)PS(0.041)T(0.624)PVACS(0.248)T(0.075)PAQLK;T(0.007)PS(0.02)T(0.972)PVACSTPAQLK 159.22 0.00063983 24995000.0 33219.0 50579.0 57504.0 58178.0 65155.0 66909.0 65269.0 66427.0 73615.0 58223.0 True False 32745.290968381498 50461.88743306451 52776.24309185915 62456.60419611871 61322.71099965855 64047.45804249691 68648.3094563303 69513.44092368595 65323.703499683754 68286.76797272908 0.4795261503877093 0.7389702124021583 0.772861927115013 0.9146223499853046 0.8980174757157684 0.9379190133595842 1.0052944588583488 1.017963552637998 0.9566085120000312 1.0 16.059318432010166 -4.440452524360106 0.5868783259857784 0.9920807039038568 3.661213752517752e-15 0.9481579442642459 0.036073717359378185 1.0835026182016692 0.21232903216331503 0.017930318725997537 0.7952665764884383 3.6269993323785463e-05 4.440452524360106 -0.9920807039038532 down TPSTPVACS(ph)TPAQLK ddPTM_PC-9_AZD4547_30min_R2 1 TPSTPVACSTPAQLK 15 0 Q6PL18;A0A0B4J211 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 TPS(0.001)T(0.013)PVACS(0.493)T(0.493)PAQLK 185.86 4.0444000000000004e-07 15037000.0 18408.0 19938.0 23943.0 30829.0 32876.0 31624.0 26539.0 29819.0 26755.0 26407.0 True False 24261.36108981417 26382.568591159572 23625.500175921723 23721.850353301954 28311.734881067703 29646.546280783936 28900.919587144635 25211.158722452335 28169.21467858494 25482.498967665237 0.9520793514246555 1.0353210893733944 0.9271265037977687 0.9309075371062558 1.1110266272155054 1.1634081225080186 1.1341477781993452 0.9893518981181082 1.105433761199358 1.0 14.637219143465327 -6.2647992670515595 24.998444608094378 1.0898506210419536 0.9641965008009445 0.5133824757730518 0.058245347573997304 246.2643742326139 1832268.0591870153 0.018535785825785894 0.021868501890512072 5.435014823831637e-07 6.2647992670515595 -0.12565412024100908 TPT(ph)PEPAEVETR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPTPEPAEVETR 12 0 F8W6G1;Q9UHY1 F8W6G1 NRBP1 Nuclear receptor-binding protein 1 T(0.259)PT(0.741)PEPAEVETR 104.59 0.004626 4556300.0 11132.0 9205.9 14368.0 11429.0 9105.1 4373.1 8450.8 8512.6 11231.0 8264.5 True False 13016.427732977914 10119.800912326427 14710.58761094343 10788.67018331793 7321.021016507243 4143.766937597431 7650.279045506311 8289.153269845248 11395.232128035464 9762.788428253993 1.3332694679019907 1.0365687002946027 1.5068018444781883 1.105080814011598 0.7498903689564599 0.4244450208103624 0.7836161872939933 0.849055915813563 1.1672108037348325 1.0 13.253077551001454 -6.100759820708188 4.207264951679054 0.8011442313336964 1.2723107652313093 0.4972371912722746 0.2093204649179641 0.19580863271808016 5.977846024302364 0.06563353868925605 0.08758594482228822 7.929397312863619e-07 6.100759820708188 0.47116653389761287 TPT(ph)QTNGSNVPFKPR ddPTM_PC-9_AZD4547_30min_R2 1 TPTQTNGSNVPFKPR 15 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347 A0A494C1K3 GTF2I General transcription factor II-I 1 T(0.321)PT(0.583)QT(0.094)NGS(0.001)NVPFKPR 79.61399999999999 0.0077065 9045700.0 24108.0 29267.0 27303.0 42749.0 30000.0 33785.0 30953.0 39862.0 35708.0 25517.0 True False 31773.842522448926 38726.98540262145 26940.9443805367 32893.87851546614 25835.017837694068 31672.418609166598 33707.75703609361 33702.243837633556 37595.45198067317 24623.657596770336 1.2903786692768346 1.572755194894398 1.0941081467957994 1.335864844050647 1.0491949758545462 1.2862597071411839 1.368917550271441 1.3686936518339978 1.5268020939993996 1.0 14.587757455132794 -7.161484433627114 6.216802363529998 1.3464449636120466 1.269125830205467 0.0037550262269717694 0.18159759742035697 0.9814881349615183 51.22100320855426 0.06889055810281268 0.05317168115284377 6.894703053419796e-08 7.161484433627114 -0.07731913340657948 TPTCQSS(ph)TDCSPYAR ddPTM_PC-9_AZD4547_30min_R2 1 TPTCQSSTDCSPYAR 15 0 O95235-2;O95235 O95235-2 KIF20A Kinesin-like protein KIF20A 1 TPTCQS(0.001)S(0.422)T(0.422)DCS(0.155)PYAR 88.76799999999999 0.021580000000000002 0.0 2199.0 1929.5 2590.9 2961.7 2649.0 3012.2 2876.0 2845.3 2410.1 2976.4 True False 2898.2362579585724 2553.17314157099 2556.542973136014 2278.925822808862 2281.2320750683866 2823.846657822454 3131.958428449751 2405.624263489508 2537.4929656833315 2872.1971419456504 1.0090659222630112 0.8889268442908655 0.8901001034365595 0.7934433850404498 0.79424634254843 0.9831660287460479 1.0904399223544021 0.8375554130173384 0.8834675477618547 1.0 11.487939060963111 -6.786128524272449 24.989899414655074 0.956992643449303 0.8722120735701313 0.19618231117620932 0.08463189287263728 424.59953534461476 429768.71031680447 0.03203533913605425 0.02826442453890355 1.6363321967678334e-07 6.786128524272449 -0.08478056987917171 TPTGEGLLDS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 2 TPTGEGLLDSPSK 13 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425;A0A0J9YWY6 O95425-2 SVIL Supervillin 1 TPTGEGLLDS(0.995)PS(0.005)K;TPTGEGLLDS(0.998)PS(0.002)K 111.66 0.00054115 58800000.0 150043.0 150483.0 139090.0 184011.0 209468.0 200462.0 173764.0 194624.0 182885.0 193003.0 True False 197753.55291172297 199123.68689454626 137245.57572020835 141590.10689160993 180386.9838808697 187927.07945036993 189228.65937452807 164549.33281460044 192551.9277328726 186246.0237155415 1.0617867107528547 1.0691432918786667 0.7369047294659411 0.7602315693346788 0.9685413963864246 1.0090259953006888 1.016014493085458 0.883505212792736 1.0338579256165075 1.0 17.506850099329164 -6.496574720888064 24.762748655698203 0.9835721395795042 0.9011887434614728 0.11321569932986197 0.10741086044185798 1652.3032319082524 1555488.3608011303 0.03675542168113734 0.04153334609237698 3.18731714676891e-07 6.496574720888064 -0.08238339611803136 TPTGEGLLDS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPTGEGLLDSPSK 13 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425;A0A0J9YWY6 O95425-2 SVIL Supervillin 1 TPTGEGLLDS(0.985)PS(0.015)K 83.869 0.0089095 10175000.0 49311.0 49208.0 60122.0 60947.0 65155.0 49753.0 63639.0 51045.0 44474.0 55439.0 True False 57658.37836335558 54093.04503565742 61555.536493954736 57532.33718283999 52388.345469080974 47143.86509484918 57610.65321353912 49705.122836648115 45124.34811345824 65489.6518451175 0.8804196806499626 0.8259785097588705 0.9399276795597125 0.8784950837561865 0.7999484497639259 0.7198673953305484 0.8796909372764394 0.7589767457338196 0.6890302031254795 1.0 15.998979340990857 -6.264893692022524 6.242881134390305 0.7948269931524077 0.8817311147010353 0.13854497002882915 0.08596717471612571 0.25488085889432566 49.565369803449656 0.025205830903695648 0.0304076758039669 5.433833263043108e-07 6.264893692022524 0.08690412154862759 TPTGEGLLDS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 2 TPTGEGLLDSPSK 13 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425;A0A0J9YWY6 O95425-2 SVIL Supervillin 1 TPTGEGLLDS(0.573)PS(0.427)K;TPTGEGLLDS(0.996)PS(0.004)K 112.12 0.00049037 68657000.0 183871.0 190634.0 181054.0 185241.0 190570.0 192159.0 163457.0 153458.0 154545.0 134861.0 True False 181248.9658221886 190192.59868551797 166168.43900865084 198864.24108586126 179361.04727503547 183940.8075145073 171920.00365875664 160588.2189059722 137138.5146690027 158171.544159013 1.145901222535802 1.2024451028581573 1.0505583661849973 1.2572693915533826 1.1339653300388863 1.1629197179082222 1.0869211941556445 1.0152788212305095 0.8670239352985935 1.0 17.27113054963764 -7.750615283897574 1.979777408619948 0.9347072422416303 1.158889218999991 0.6996472629413149 0.05900461142908596 0.17517393543586232 1.3430259173204122 0.039455302867842684 0.016353468497209166 1.7757618279944432e-08 7.750615283897574 0.22418197675836082 TPTGEGLLDSPS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPTGEGLLDSPSK 13 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425;A0A0J9YWY6 O95425-2 SVIL Supervillin 1 TPTGEGLLDS(0.402)PS(0.598)K 121.92 0.00018977 10743000.0 50487.0 45673.0 39853.0 46861.0 56907.0 50804.0 54022.0 37923.0 38992.0 35977.0 True False 59033.45193629685 50207.11359765856 40803.24666334414 44235.53009541186 45756.481860317566 48139.748804669405 48904.645074589665 36927.561432739865 39562.184234383334 42499.34530622472 1.3890437961087942 1.1813620477185305 0.9600911818603437 1.0408520361120208 1.0766396877557496 1.1327174208873885 1.1507152574283723 0.8688971833956987 0.9308892631009261 1.0 15.375152996547131 -4.911310628059765 2.820205223403176 1.0272918015802432 1.4084600448751907 0.6540093392856967 0.0836435986445689 0.22310857860815145 2.9840797695706227 0.02397237151420753 0.1726798876648109 1.22656162215922e-05 4.911310628059765 0.3811682432949475 TPTHQPPKPGS(ph)PGRPACPLSNLLLQSYEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPTHQPPKPGSPGRPACPLSNLLLQSYEER 30 2 Q96F63 Q96F63 CCDC97 Coiled-coil domain-containing protein 97 1 T(0.027)PT(0.027)HQPPKPGS(0.645)PGRPACPLS(0.3)NLLLQSYEER 52.92 0.0021414999999999997 3782800.0 10020.0 9235.3 9415.1 14641.0 10309.0 14017.0 14257.0 12050.0 14238.0 8331.7 True False 11716.188095979054 10152.119550028596 9639.591690965586 13820.712236762442 8289.025453775703 13281.923844481751 12906.473748258577 11733.700268030361 14446.203814350367 9842.17125629909 1.190406851382572 1.031491861466151 0.9794171875231442 1.4042340736468129 0.8421948001027356 1.349491235074901 1.3113441548782543 1.1921861510508336 1.467786267700295 1.0 13.264760904611531 TPTPSTPGDTQPNT(ph)PAPVPPAEDGIK ddPTM_PC-9_Lapatinib_30min_R1 1 TPTPSTPGDTQPNTPAPVPPAEDGIK 26 0 Q14839-2;A0A2R8Y8C1;A0A0C4DGG9;A0A2R8Y521;A0A2R8Y212;F5GWX5;A0A2U3TZM0;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8YER1;Q14839;A0A2R8YD40;A0A2R8YE38;A0A2R8YDW2;A0A2R8Y5M9;A0A2R8Y4X2;A0A2R8Y7M9 Q14839-2 CHD4 Chromodomain-helicase-DNA-binding protein 4 1 T(0.008)PT(0.008)PS(0.007)T(0.007)PGDT(0.023)QPNT(0.946)PAPVPPAEDGIK 54.255 0.011358 3475800.0 12321.0 19024.0 13768.0 14647.0 16931.0 21133.0 17362.0 15960.0 17197.0 14122.0 True False 12145.300280605328 18979.951096831086 12636.048186016926 15724.189240959658 15935.151867626735 20229.19085342911 18260.91940708155 16701.55986484453 15260.09276756182 16562.96888361782 0.7332803898833656 1.14592687036947 0.7629096132949358 0.9493581344895367 0.9620951400438813 1.2213505317538509 1.1025148652632648 1.0083675204729623 0.9213380085894712 1.0 14.015673676165186 -6.5343540306417305 24.94688183543875 1.0586133927468655 0.9121696486867634 0.23834309282291355 0.12787524057985383 326.3435397382025 709454.8027021204 0.04135475207058632 0.04138526102216693 2.921769622030458e-07 6.5343540306417305 -0.14644374406010208 TPTS(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 1 TPTSPLK 7 0 O60264 O60264 SMARCA5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 1 T(0.002)PT(0.049)S(0.948)PLK 83.647 0.020712 303360000.0 411300.0 424670.0 492510.0 538200.0 537850.0 437070.0 517230.0 524220.0 476870.0 419590.0 True False 542084.8444285407 561936.2726255261 485978.99559968314 414126.30510711065 463178.8114667932 409739.9438066723 563262.4679927207 443213.8443772081 502076.3746506001 404900.2818132566 1.3388107363149595 1.387838679956009 1.2002436585702865 1.0227859147258118 1.1439330429520795 1.0119527256729541 1.3911140428706887 1.0946246873239323 1.2400000622428855 1.0 18.62720712157676 -5.378490861827204 4.251071852092852 1.1381686515814262 1.3623271292437549 0.3997053891439075 0.1125028481773845 0.21993321573203248 6.529483215740436 0.029320833210132496 0.06508507069024655 4.183204906162216e-06 5.378490861827204 0.22415847766232866 TPTS(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 1 TPTSPLK 7 0 O60264 O60264 SMARCA5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 1 T(0.005)PT(0.156)S(0.84)PLK 76.17 0.031649000000000004 368420000.0 1132500.0 934990.0 927960.0 896280.0 893690.0 873500.0 857360.0 767910.0 996040.0 795820.0 True False 1116350.3423249347 932825.0881006153 851666.7108291886 962195.4211024335 841124.9112621427 836142.4412279533 901749.9057053011 803589.901993282 883855.4864338124 933376.4266365076 1.1960344299113996 0.9994093074132169 0.9124579178608934 1.0308760684794422 0.9011636540824154 0.8958255397996879 0.9661160063307201 0.8609494294698216 0.9469442994386009 1.0 19.832099505479952 -4.749702145184275 2.4488442634527092 0.9353945454642748 1.2689862807907215 0.7173314786180338 0.04830348953130366 0.31047192144348934 2.160012105258933 0.01232885111434206 0.22862136617663623 1.7794994365017778e-05 4.749702145184275 0.3335917353264467 TPTS(ph)SPASSPLVAK ddPTM_PC-9_AZD4547_30min_R2 1 TPTSSPASSPLVAK 14 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 T(0.002)PT(0.04)S(0.594)S(0.363)PAS(0.002)SPLVAK 169.17 0.00032068 58498000.0 150980.0 113390.0 191630.0 217140.0 217500.0 149930.0 162040.0 201050.0 165980.0 195100.0 True False 198988.4994209119 150041.1000376959 189088.8609911821 167081.72777955778 187303.8793232823 140554.85339861948 176461.24608692538 169982.3421693903 174753.3639451142 188269.60838381838 1.0569337299265067 0.7969480646701754 1.0043514862244443 0.8874598997355663 0.994870499445841 0.7465615645838888 0.9372795089007689 0.9028666051232948 0.9282080387018753 1.0 17.522440604645517 -8.69547364765328 3.6799432563539995 0.9999967571386512 0.9117255558592288 0.07276851444318666 0.0885186742677541 3.120462569593114 63.384889053382146 0.07899868666711132 0.02076177445403175 2.016166304941708e-09 8.69547364765328 -0.08827120127942245 TPTS(ph)SPASSPLVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPTSSPASSPLVAK 14 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 T(0.243)PT(0.02)S(0.363)S(0.363)PAS(0.009)S(0.002)PLVAK 69.92 0.028594 3216300.0 27835.0 26628.0 28798.0 30629.0 42636.0 38456.0 36764.0 37965.0 32634.0 29321.0 True False 32546.91573369029 29271.45186167871 29484.653537023172 28912.956430557784 34281.781865086916 36439.29966208107 33281.447771689585 36968.45897724254 33111.21051253758 34636.6651950917 0.9396665513371205 0.8451001762671632 0.8512555516228332 0.8347500045892117 0.9897541137980259 1.052044111545843 0.9608733284290267 1.0673215440636956 0.9559583847358871 1.0 15.080012414172348 -6.3297508736778125 5.5834008834685855 1.0092283265018014 0.865072538097344 0.7163520445052683 0.0421228720168227 0.10920174310716305 6.520930212726457 0.012557840539994376 0.014354864803479996 4.6800352729756044e-07 6.3297508736778125 -0.14415578840445742 TPTSPLS(ph)PSSQK ddPTM_PC-9_AZD4547_30min_R2 1 TPTSPLSPSSQK 12 0 Q5VT06 Q5VT06 CEP350 Centrosome-associated protein 350 1 TPTSPLS(0.954)PS(0.017)S(0.028)QK 103.83 0.004730699999999999 0.0 10961.0 12708.0 13533.0 17704.0 18448.0 15053.0 14054.0 16759.0 15273.0 13349.0 True False 14446.36999703678 16815.612481515487 13353.543577694882 13622.61632407336 15886.81363565934 14111.733530376949 15304.77877379444 14169.28163350812 16080.299599552516 12881.655573119378 1.1214684257808094 1.3053921823996941 1.036632558749685 1.0575206150131953 1.2332897386894068 1.0954906727846705 1.1881065043946277 1.0999581189762346 1.248310010175079 1.0 13.653030402632126 -11.966082799224736 1.8446830538426382 6.607710995019117e-05 1.1522028682438348 0.2340286195631608 0.08353407208665925 1057529.441700271 86584.01568344171 4406139.958788086 0.02038243317152753 1.0812277931233307e-12 11.966082799224736 1.1521367911338847 TPTSPLS(ph)PSSQK ddPTM_PC-9_Lapatinib_30min_R1 1 TPTSPLSPSSQK 12 0 Q5VT06 Q5VT06 CEP350 Centrosome-associated protein 350 1 T(0.001)PT(0.025)S(0.017)PLS(0.938)PS(0.015)S(0.004)QK 119.25 0.00054727 3613500.0 16335.0 13162.0 9967.3 11746.0 13964.0 15063.0 10759.0 10462.0 10983.0 12339.0 True False 16102.059904527869 13131.524197670873 9147.827068890647 12609.840023507346 13142.66497428029 14418.79060356801 11316.04837580869 10948.102713408733 9745.978883882737 14471.779709315982 1.1126523639772115 0.9073883420998773 0.6321148644214005 0.8713399648690036 0.9081581697805905 0.9963384527119452 0.7819389600384921 0.7565139142051107 0.6734471557502298 1.0 13.820954731959532 -7.3340959213867 24.040256943314528 0.782683987942142 0.8910445591776576 0.10499276929262724 0.13712550574602023 231.88536015484956 76723.02858843902 0.05913943855797048 0.03987179362099206 4.6334457083675056e-08 7.3340959213867 0.10836057123551557 TPTSS(ph)PAS(ph)SPLVAK ddPTM_PC-9_Lapatinib_30min_R1 1 TPTSSPASSPLVAK 14 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 2 T(0.008)PT(0.006)S(0.008)S(0.978)PAS(0.675)S(0.325)PLVAK 138.21 5.9313e-05 0.0 24254.0 21641.0 24164.0 26876.0 29320.0 30356.0 28194.0 31258.0 36507.0 27240.0 True False 23908.133512361135 21590.89159411909 22177.32919573742 28852.550695707763 27595.45524533789 29057.744643292193 29653.74736569852 32710.360792939242 32395.1972242472 31948.397704981548 0.7483359175985612 0.6758051465833773 0.694160921637689 0.9030985203745894 0.8637508365884363 0.90952118824918 0.9281763561205063 1.0238498060213794 1.013985036851973 1.0 14.963455957637427 -6.216949262030782 0.6151118498287386 1.013811752898339 0.6629809648093752 0.8616221870785165 0.04562737690690569 0.34726375807093224 0.2708973137441895 0.03284185659501592 0.06799758810380754 6.068072178194745e-07 6.216949262030782 -0.35083078808896384 TPTSS(ph)PASSPLVAK ddPTM_PC-9_AZD4547_30min_R2 3 TPTSSPASSPLVAK 14 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 T(0.007)PT(0.006)S(0.136)S(0.792)PAS(0.048)S(0.012)PLVAK;TPT(0.002)S(0.011)S(0.969)PAS(0.015)S(0.003)PLVAK;T(0.01)PT(0.007)S(0.054)S(0.832)PAS(0.087)S(0.009)PLVAK 133.16 1.1015e-05 66221200.0 194431.0 154466.0 219371.0 275404.0 243402.0 219711.0 213953.0 241551.0 196083.0 231240.0 True False 256256.01358396662 204394.11375273636 216461.99720553472 211913.86274938443 209609.83372434718 205972.43643743132 232994.40251811862 204224.84323978281 206447.54706862164 223144.35798397864 1.1483867031151436 0.9159725820511737 0.9700536422304538 0.9496716146621079 0.9393463299636587 0.9230456835131802 1.0441420281611924 0.9152140125113348 0.9251748461569627 1.0 17.767617804166008 -4.754819871338441 24.998925980212338 0.9527917321248225 1.1483870329331978 0.6880220215852213 0.03934113619680742 125.987071632828 475753.6509192945 0.00948484399883484 0.08902558232732571 1.7586528843445988e-05 4.754819871338441 0.19559530080837528 TPTSS(ph)PASSPLVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TPTSSPASSPLVAK 14 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 T(0.295)PT(0.108)S(0.242)S(0.326)PAS(0.022)S(0.007)PLVAK;T(0.006)PT(0.002)S(0.049)S(0.926)PAS(0.013)S(0.003)PLVAK;T(0.004)PT(0.002)S(0.014)S(0.969)PAS(0.004)S(0.006)PLVAK;T(0.018)PT(0.057)S(0.057)S(0.866)PAS(0.001)SPLVAK;T(0.006)PT(0.029)S(0.016)S(0.546)PAS(0.336)S(0.067)PLVAK 179.65 5.6795e-05 93815000.0 185417.0 191230.0 249070.0 265830.0 362420.0 347849.0 381243.0 406864.0 366345.0 284530.0 True False 216804.43594732045 210214.05060495832 255008.77340323568 250936.40693248794 291406.40265373903 329607.18608683284 345128.9030797046 396184.251108041 371702.1025683505 336113.0366617599 0.6450342959041393 0.6254266501912055 0.7586994421161303 0.7465833798794671 0.8669892889248136 0.9806438612451855 1.0268239117039 1.17872325049603 1.1058842175836365 1.0 18.35858697531694 -6.523554333247383 0.8880243841014609 1.109409352478308 0.6443095810493339 0.9206356019790907 0.051733831538782415 0.1439580478212323 0.24900965163138555 0.028976486423905372 0.034912432545635246 2.995336831604123e-07 6.523554333247383 -0.4650997714289741 TPTSS(ph)PASSPLVAK ddPTM_PC-9_Lapatinib_30min_R1 2 TPTSSPASSPLVAK 14 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 TPT(0.001)S(0.044)S(0.955)PASSPLVAK;TPTSS(0.965)PAS(0.027)S(0.008)PLVAK 188.09 3.868e-06 63058100.0 190203.0 145001.0 187767.0 154768.0 198763.0 214341.0 193929.0 191417.0 231122.0 181033.0 True False 187490.67034104178 144665.2590933348 172329.52206158047 166150.15501091318 187072.15112309327 205174.13508327518 203969.69471811535 200310.9326221141 205090.6065374439 212324.31283869033 0.8830391010542656 0.6813409974544069 0.8116334853865973 0.7825300493831945 0.8810679691930432 0.9663242628231306 0.9606516182302577 0.9434196675078695 0.9659308620641005 1.0 17.695910055305582 -6.481105699752588 2.273009314103765 0.9644898327348519 0.7813038127286334 0.749547574944423 0.04821934880799449 0.14377211668327544 1.4797069969648131 0.01622521680331448 0.017934192991228025 3.3028914459824406e-07 6.481105699752588 -0.18318602000621853 TPTSSPAS(ph)SPLVAK ddPTM_PC-9_AZD4547_30min_R2 1 TPTSSPASSPLVAK 14 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 TPTSS(0.001)PAS(0.601)S(0.397)PLVAK 124.47 3.8015e-05 16347000.0 61487.0 55680.0 86331.0 107030.0 107570.0 96027.0 75437.0 107460.0 79436.0 102130.0 True False 81038.58699094984 73677.4711182549 85186.19453232658 82355.88709701612 92635.76229335822 90022.41650976588 82150.74685916683 90854.52618514148 83634.82478819195 98554.45978595258 0.8222721444260876 0.7475812994995128 0.8643565670933601 0.8356383595007507 0.9399449045182836 0.9134281361318688 0.8335568683303376 0.9218712819538116 0.8486153236478173 1.0 16.588633537124622 -1.5228787452803376 0.08678297292762305 1.062439765163199 0.32413980835035316 0.5195309844102229 0.047296007354898986 140.28327604189622 0.882771151917418 1.0289996775182744 12.34726556005895 0.029999999999999995 1.5228787452803376 -0.7382999568128458 TPTSSPAS(ph)SPLVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPTSSPASSPLVAK 14 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 TPTSSPAS(0.5)S(0.5)PLVAK 85.271 0.006959600000000001 10543000.0 54272.0 61840.0 57751.0 59757.0 88609.0 94969.0 107840.0 88442.0 115090.0 78138.0 True False 63459.17767913919 67979.06651367778 59128.00286188716 56409.009024807965 71246.70253502863 89988.65845663035 97624.61450601136 86120.49121204499 116772.9735211116 92303.80085993222 0.6875034081796508 0.7364709348950172 0.6405803695084218 0.6111233611106293 0.7718718175337438 0.9749182332500584 1.0576445779752157 0.9330113214160034 1.2650938794850983 1.0 16.49410243553399 -6.752804930952928 2.296633839720033 1.0577447481135032 0.6711337103009178 0.8216723169136497 0.08483221602573546 0.11996934485721042 1.2991810029105866 0.03191089828417881 0.029617969460070236 1.7668312378464176e-07 6.752804930952928 -0.3866110378125853 TPTSSPAS(ph)SPLVAK ddPTM_PC-9_Lapatinib_30min_R1 1 TPTSSPASSPLVAK 14 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 TPTSSPAS(0.88)S(0.12)PLVAK 116.9 0.00013785 4861700.0 10676.0 12403.0 9394.2 12195.0 16891.0 24307.0 20675.0 20263.0 27763.0 22382.0 True False 10523.758282261384 12374.28161553805 8621.845138660667 13091.860981327438 15897.504588983711 23267.446272384503 21745.450336448055 21204.492953718334 24636.038582649224 26250.69887785964 0.4008944040395561 0.4713886541883563 0.3284424989512375 0.4987242831987751 0.6056030989099488 0.8863553073632158 0.828376053438661 0.8077687017926454 0.9384907692277766 1.0 14.680068212012038 -6.528180719154475 1.7609319250943236 0.8855730443140213 0.40937716645956723 0.9197545084251049 0.06542592654728462 0.09207120912613478 0.5782209558676271 0.02458873435634031 0.02672391621366668 2.9635979168913634e-07 6.528180719154475 -0.47619587785445405 TPTSSPASS(ph)PLVAK ddPTM_PC-9_AZD4547_30min_R2 2 TPTSSPASSPLVAK 14 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 T(0.004)PT(0.004)S(0.003)S(0.004)PAS(0.054)S(0.931)PLVAK;TPTSSPAS(0.156)S(0.844)PLVAK 131.08 1.7466e-05 23062600.0 86342.0 73047.0 123654.0 167009.0 138811.0 143145.0 102059.0 136834.0 123009.0 142813.0 True False 113796.95997483344 96658.0142380596 122014.26716591162 128507.65531332856 119539.48870227151 134194.12052121246 111142.0532855193 115689.44943251072 129511.00461214944 137813.16033889426 0.825733621484313 0.7013699852783967 0.8853600546266276 0.9324773845786377 0.8674025645178861 0.9737395194422487 0.8064690847536734 0.8394659054913228 0.9397578888233235 1.0 17.072354137871528 -5.354217035721042 6.763752606353692 0.899057228637487 0.7642671904222137 0.44787087351153454 0.06284104787541091 0.2057188401294616 12.620208910222484 0.015964872960242887 0.03361816660383031 4.423672470836246e-06 5.354217035721042 -0.13479003821527336 TPTSSPASS(ph)PLVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPTSSPASSPLVAK 14 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 TPTSS(0.002)PAS(0.26)S(0.738)PLVAK;T(0.001)PTS(0.001)S(0.002)PAS(0.237)S(0.759)PLVAK 124.42 3.8179e-05 6636800.0 41482.0 50779.0 50428.0 64244.0 90206.0 104754.0 107820.0 105842.0 103113.0 88602.0 True False 48504.083293153955 55820.00353328015 51630.394769255 60644.616961858206 72530.78184918928 99260.51583112242 97606.50905079868 103063.75964886876 104620.83255436945 104664.84122695413 0.463422890863401 0.5333214370644355 0.4932926297313173 0.5794172737563044 0.6929813392819687 0.9483654173409289 0.9325625291796866 0.9847027754562432 0.9995795276420546 1.0 16.67541737128046 -6.560848754065812 1.479108738896504 0.9872503334962526 0.4988870455176579 0.982376761479747 0.02903150391476783 0.044398450937934326 0.1998812044760892 0.01149125621369888 0.012316270593510321 2.748851292124534e-07 6.560848754065812 -0.4883632879785947 TPTSSPASS(ph)PLVAK ddPTM_PC-9_Lapatinib_30min_R1 3 TPTSSPASSPLVAK 14 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 TPTSSPAS(0.223)S(0.777)PLVAK;TPTSS(0.007)PAS(0.043)S(0.95)PLVAK;TPTS(0.001)S(0.01)PAS(0.203)S(0.785)PLVAK 197.06 5.2502e-08 39736000.0 124541.0 98574.0 117642.0 128086.0 198343.0 236651.0 222463.0 203420.0 277244.0 247642.0 True False 122765.02250197768 98345.75795936865 107969.92887125211 137505.87172237036 186676.85469734165 226529.98839042496 233981.04562018113 212871.63582122003 246017.8612112525 290446.58973777626 0.4226767565520861 0.3386018684129089 0.3717376367501183 0.4734291142702509 0.6427235205821457 0.7799368159045796 0.8055906107605744 0.7329114657996392 0.8470330515271832 1.0 18.147913365072434 -6.402858300791641 1.2790809675089576 0.8320872323144646 0.36310480614969864 0.908152756054247 0.06541282366055404 0.12224223046970305 0.4112377946490439 0.026654772261479116 0.03342739062337664 3.9549563915509393e-07 6.402858300791641 -0.46898242616476593 TPTVPDS(ph)PGYMGPTR ddPTM_PC-9_AZD4547_30min_R2 3 TPTVPDSPGYMGPTR 15 0 A0A087WXN9;Q765P7 A0A087WXN9 MTSS1L MTSS1-like protein 1 TPT(0.001)VPDS(0.998)PGY(0.001)MGPTR;T(0.003)PT(0.001)VPDS(0.985)PGY(0.005)MGPT(0.006)R;T(0.004)PT(0.002)VPDS(0.971)PGY(0.005)MGPT(0.019)R 97.823 0.0020919 80317000.0 82653.0 71338.0 88553.0 139514.0 105086.0 103457.0 79901.0 101320.0 72034.0 91538.0 True False 108934.93471080031 94396.61340937606 87378.72936049775 107351.20276981319 90496.62281639753 96987.81743520958 87012.03421125322 85663.32210197748 75841.5701796744 88333.28248199864 1.2332263859095247 1.068641521711967 0.989193732026256 1.2152973347468456 1.024490659393754 1.0979759237971785 0.9850424637959687 0.9697740160333647 0.858584307620744 1.0 16.430669502867083 -7.384584141622195 1.4618516236804497 0.9285877327550304 1.105962401111794 0.48250314479626977 0.07792977043494057 0.36969195237961644 1.525984494073037 0.04880084360104222 0.0259806795971239 4.124923117754653e-08 7.384584141622195 0.17737466835676352 TPTVPDS(ph)PGYMGPTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPTVPDSPGYMGPTR 15 0 A0A087WXN9;Q765P7 A0A087WXN9 MTSS1L MTSS1-like protein 1 TPT(0.008)VPDS(0.991)PGY(0.001)MGPTR;TPTVPDS(1)PGYMGPTR 98.676 0.0043046000000000004 12824000.0 17039.1 15965.3 18003.5 24818.5 44186.0 56794.0 62260.0 64686.0 51447.0 49513.0 True False 19923.483092434784 17550.22947300808 18432.771718653963 23427.999907662634 35528.07049185502 53815.62265987705 56362.28207663456 62988.0610404823 52199.315046838274 58489.31495530764 0.3406345775746997 0.30005872844327913 0.31514767667801646 0.40055179181982625 0.6074283913053594 0.9200932290111141 0.9636338213176481 1.0769156911584998 0.8924589916418815 1.0 15.83588547144272 -6.561368751733165 1.6410824110644375 0.9953319380701929 0.3170999902413813 0.9773637015517221 0.04561362814399926 0.046710315945824255 0.25699639983257583 0.01750203111647974 0.018629155212672856 2.7455619552231684e-07 6.561368751733165 -0.6782319478288117 down TPTVPDS(ph)PGYMGPTR ddPTM_PC-9_Lapatinib_30min_R1 2 TPTVPDSPGYMGPTR 15 0 A0A087WXN9;Q765P7 A0A087WXN9 MTSS1L MTSS1-like protein 1 TPTVPDS(0.999)PGY(0.001)MGPTR;TPT(0.001)VPDS(0.999)PGYMGPTR 119.65 8.266299999999999e-05 41696000.0 33256.0 30364.0 35846.0 27575.0 66809.0 89116.0 82446.0 87020.0 107490.0 85494.0 True False 32781.7633415965 30293.6940235586 32898.88024956148 29602.957487503412 62879.425971547644 85304.71641954241 86714.65046862376 91063.26688212864 95383.34428011968 100271.52398640566 0.3269299402095544 0.30211662114226645 0.32809793789532665 0.2952279601486544 0.6270915557249588 0.8507372086127625 0.8647983696785153 0.9081667781819548 0.9512505693346328 1.0 16.613552428976213 -6.54210817901166 1.858585791053908 0.9214676772198725 0.3045791632803028 0.9815787895428935 0.038901993484217925 0.041643959080564064 0.29126181426999537 0.014834118069372527 0.015906993496376934 2.870065584382488e-07 6.54210817901166 -0.6168885139395697 down TPVAS(ph)THSISSAATPDR ddPTM_PC-9_AZD4547_30min_R2 4 TPVASTHSISSAATPDR 17 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;A2SY06 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 T(0.001)PVAS(0.921)T(0.071)HS(0.007)ISSAATPDR;TPVAS(0.957)T(0.038)HS(0.003)IS(0.001)SAAT(0.001)PDR;T(0.001)PVAS(0.499)T(0.499)HSISSAATPDR;T(0.285)PVAS(0.368)T(0.341)HS(0.006)ISSAATPDR 84.40299999999999 0.0027622 81622300.0 59531.6 85227.7 137692.1 252080.2 201802.8 200445.1 138986.1 234257.1 161870.2 207497.0 True False 78461.41046579657 112775.88730648873 135866.21278758012 193967.0044902664 173785.96458988742 187911.2362100416 151355.59364824757 198058.04788763478 170426.32830743713 200232.59318717106 0.3918513425656598 0.5632244257111 0.6785419427724072 0.9687084475250851 0.867920461018241 0.9384647784808348 0.7558988835886732 0.9891399034246957 0.851141792625779 1.0 17.611317304765798 -5.325225476635473 1.6346743562554917 0.9041056660578738 0.4057180293281484 0.8347988988140782 0.07818000625749084 0.16645834473595017 0.7730044712670113 0.021905996425222403 0.09303767462145056 4.7290567245513646e-06 5.325225476635473 -0.4983876367297254 TPVAS(ph)THSISSAATPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPVASTHSISSAATPDR 17 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;A2SY06 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 T(0.049)PVAS(0.825)T(0.118)HS(0.007)ISSAATPDR 52.464 0.038380000000000004 23375000.0 23580.0 37700.0 54012.0 42265.0 60256.0 58375.0 47413.0 46009.0 41575.0 39644.0 True False 27571.628273771068 41442.606849379874 55299.85092165065 39897.02907497879 48449.26935131527 55313.71223668561 42921.697399606055 44801.31250056508 42182.95572282742 46831.14337826868 0.5887455715327524 0.884936900101626 1.1808349515402128 0.8519336961884307 1.0345523482093213 1.1811309365201865 0.9165203815955357 0.9566563886491503 0.9007458003342668 1.0 15.515180641289634 -4.82852888882168 3.5575145212636126 1.0019891357055644 0.5609014380956114 0.5886036156722865 0.10427466171851066 0.17527804697369959 3.717237814549657 0.02625064606607411 0.19132468389369187 1.4841271541711641e-05 4.82852888882168 -0.4410876976099529 TPVAS(ph)THSISSAATPDR ddPTM_PC-9_Lapatinib_30min_R1 3 TPVASTHSISSAATPDR 17 0 J3KNR0;P27448-8;P27448-3;P27448-4;P27448-2;P27448;H0YIY6;P27448-6;P27448-7;A2SY06 J3KNR0 MARK3 MAP/microtubule affinity-regulating kinase 3 1 T(0.004)PVAS(0.976)T(0.018)HS(0.002)ISSAATPDR;T(0.355)PVAS(0.627)T(0.018)HSISSAATPDR;TPVAS(0.786)T(0.213)HS(0.001)ISSAATPDR 170.48 1.0735999999999998e-11 20102900.0 35082.9 28866.8 32017.6 30406.9 31990.7 29661.4 27082.1 22906.0 41636.0 21269.1 True False 34582.61141258408 28799.9606981709 29385.236519510123 32643.124860444866 30109.06992213609 28392.85106610054 28484.278624266994 23970.296382464196 36946.5152334828 24945.435595705676 1.3863302278248224 1.1545182519534265 1.1779804929350983 1.308581072284997 1.2069971601265332 1.138198247016714 1.1418633487069885 0.9609091126310358 1.4810932080834498 1.0 14.606488241370334 -6.623739875730828 4.037416526948948 1.1419764090796427 1.2453890050838892 0.1184892206708289 0.14309926263944484 0.5358940808485421 16.2205262202994 0.04669531786821224 0.04667074439585787 2.3782643411900507e-07 6.623739875730828 0.10341259600424646 TPVEPEVAIHR ddPTM_PC-9_AZD4547_30min_R2 2 TPVEPEVAIHR 11 0 P60866;P60866-2;E5RIP1;E5RJX2 P60866 RPS20 40S ribosomal protein S20 0 ; 89.9 0.0075791 15871600.0 77735.0 81044.0 108108.0 127443.0 105097.0 111495.0 102598.0 117967.0 97811.0 100708.0 False True 102453.11301155486 107239.88809820112 106674.4172834877 98062.98532472234 90506.09565627121 104523.20002453841 111729.02324133796 99737.91076198166 102981.08977488597 97182.24357312958 1.0542369598048942 1.103492615062989 1.0976739511391838 1.009062784714679 0.9313028010941672 1.0755380425631433 1.1496855714929233 1.0262976763541063 1.0596698119795183 1.0 16.568405118800953 -8.723018759551909 0.005283167609113415 9.615516872175221e-06 2.081852619957385 0.056093880050806066 0.057195209677297715 27700.713215307045 79.37498945150467 15784.917604098255 15487.307368366375 1.892261879748616e-09 8.723018759551909 2.081843004440513 TPVEPEVAIHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TPVEPEVAIHR 11 0 P60866;P60866-2;E5RIP1;E5RJX2 P60866 RPS20 40S ribosomal protein S20 0 ; 152.04 4.7186000000000005e-05 12903400.0 48162.0 68361.0 64948.0 57905.0 65597.0 48032.0 60472.0 49713.0 42831.0 34618.0 False True 56314.87535714 75147.42829789013 66496.60663666157 54660.77058054294 52743.73874200461 45513.117364496546 54743.65438063357 48408.08642527743 43457.32234670884 40893.96936406279 1.3770948683359887 1.8376163885897792 1.6260736649130012 1.336646244680231 1.2897681384863382 1.1129542588373194 1.3386730423078408 1.1837463366375478 1.0626829095465284 1.0 15.319600484084434 -5.9812156009237745 1.9447807671415405 1.1731413918938525 1.6420952045469999 0.6722879840658105 0.13979452091102582 0.1921965581994886 1.464612343489757 0.044031818034563464 0.07168820028728741 1.0442017075810852e-06 5.9812156009237745 0.4689538126531474 TPVEPEVAIHR ddPTM_PC-9_Lapatinib_30min_R1 2 TPVEPEVAIHR 11 0 P60866;P60866-2;E5RIP1;E5RJX2 P60866 RPS20 40S ribosomal protein S20 0 ; 181.53 0.0013732000000000002 40766000.0 132900.0 151125.0 152477.0 162583.0 172838.0 182746.0 157267.0 149793.0 151151.0 156136.0 False True 131004.82162912472 150775.07934759252 139940.92963824063 174539.89618098887 162672.00865258215 174930.37958173285 165409.51574665913 156752.92962623187 134126.78268940726 183123.89956185708 0.7153889904188767 0.8233500908856656 0.7641871430930852 0.9531246145292541 0.8883166481370908 0.9552569599067731 0.9032655821682399 0.8559938380587105 0.7324373443898885 1.0 17.48246056447588 -5.746344774939333 24.992387618259933 0.8945007490313955 0.7732128224037784 0.4066376735891606 0.07215218483623528 261.5281937656186 433012.94410562096 0.01976342923297309 0.03406025906444628 1.793309400525656e-06 5.746344774939333 -0.12128792662761712 TPVQYSQQQNS(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 4 TPVQYSQQQNSPQK 14 0 P46013 P46013 MKI67 Antigen KI-67 1 TPVQYS(0.138)QQQNS(0.862)PQK;TPVQYS(0.003)QQQNS(0.996)PQK;TPVQYSQQQNS(1)PQK;TPVQYSQQQNS(1)PQK 214.54 2.6302e-15 296463000.0 79685.1 133687.1 102316.2 126184.5 108265.7 89008.9 85250.0 84866.7 66446.0 94680.7 True False 105023.30424695545 176898.8406812725 100959.42033578244 97094.61305609113 93234.8763570144 83443.1594122082 92837.084848867 71752.50155775681 69958.19990780254 91365.95751156204 1.1494795994850173 1.936157027182543 1.1050004080897022 1.0627001095435809 1.0204553084798116 0.9132850099190255 1.0161014821862815 0.785330811518905 0.765692187913092 1.0 16.479369104157456 -5.459778979100545 6.088280729738054 0.9443472540231062 1.545363680007319 0.589483717996969 0.19913665285604729 0.1392026344964837 10.219259500068379 0.05049314359708295 0.10534703940389 3.4691335648210775e-06 5.459778979100545 0.6010164259842128 TPVQYSQQQNS(ph)PQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 TPVQYSQQQNSPQK 14 0 P46013 P46013 MKI67 Antigen KI-67 1 TPVQYSQQQNS(1)PQK;TPVQYSQQQNS(1)PQK;TPVQYSQQQNS(1)PQK;TPVQY(0.017)S(0.024)QQQNS(0.959)PQK;TPVQYSQQQNS(1)PQK;TPVQYSQQQNS(1)PQK 164.01 1.4804000000000001e-05 181394800.0 244082.0 263081.0 209192.0 356591.0 389005.0 246255.0 392890.0 351033.0 286431.0 188796.0 True False 285400.26176075457 289197.94303824136 214179.9306450783 336612.36235362024 312782.2627457581 233340.95429284853 355672.61492272624 341818.755700208 290619.5115007856 223023.22029168642 1.2796885516561316 1.2967167394498504 0.9603481214420534 1.5093153166444886 1.4024650094132716 1.0462630482497195 1.5947784022558325 1.5326599412077 1.3030908222053816 1.0 17.76683440007867 -5.780127064189869 24.999143759604813 1.364245124184909 1.1906974947802067 0.11010736593687398 0.20341158653470354 482.4495930370656 645387.7121314235 0.056934189668404696 0.08461158882195104 1.6591014229809364e-06 5.780127064189869 -0.17354762940470225 TPVQYSQQQNS(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 2 TPVQYSQQQNSPQK 14 0 P46013 P46013 MKI67 Antigen KI-67 1 TPVQYSQQQNS(1)PQK;TPVQYSQQQNS(1)PQK 219.85 9.4608e-16 98546000.0 145180.0 234838.0 126032.0 66317.0 89492.0 110436.0 231302.0 178431.0 110825.0 62702.0 True False 143109.7065772484 234294.24703940316 115670.1354575889 71194.17340702673 84228.25650804151 105712.9097188897 243277.6857906221 186721.55565439037 98342.72146101297 73539.95715483665 1.9460129175209373 3.1859448401105555 1.572888262826264 0.9681019157670852 1.1453400269285021 1.4374894113184435 3.308102087663808 2.5390490133309775 1.337269224320524 1.0 16.166240715561386 TPVS(ph)GSLKSPVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TPVSGSLKSPVPR 13 1 A0A0C4DG98;Q8NI27;Q8NI27-2;H0Y7U4;H7C477 A0A0C4DG98 THOC2 THO complex subunit 2 1 T(0.001)PVS(0.566)GS(0.39)LKS(0.043)PVPR 53.981 0.039412 64719000.0 73147.0 69908.0 62429.0 95113.0 87059.0 81193.0 78874.0 79251.0 87335.0 61970.0 True False 85529.34238089625 76848.00423412332 63917.54412330091 89784.12697050648 70000.4139082608 76935.09614789243 71402.483721691 77170.74522337536 88612.10915341269 73204.67044574993 1.1683590932122263 1.0497691440476242 0.8731347840800476 1.2264808573524437 0.9562287963598755 1.050958848382591 0.9753815335403431 1.0541778926600671 1.2104707064978977 1.0 16.15964807469777 -10.72385805375358 4.779457307613221 0.9999916048496204 1.055324024259585 0.025681965101774895 0.10751599493187908 9.261893550838193e-06 1.5484365271662149e-06 0.10024756179543773 0.024309916307020375 1.8886085272947883e-11 10.72385805375358 0.055332419409964584 TPVS(ph)PQVTDSK ddPTM_PC-9_AZD4547_30min_R2 1 TPVSPQVTDSK 11 0 C9JM94;B5MCC4;E7EX78;O14901-2;O14901 C9JM94 KLF11 Krueppel-like factor 11 1 T(0.01)PVS(0.99)PQVTDSK 107.99 0.0022404 3686600.0 14018.0 14763.0 23764.0 31723.0 32017.0 26271.0 19172.0 25923.0 18276.0 21682.0 True False 18475.43240748669 19534.85104380022 23448.873832878224 24409.752465464273 27571.99220364837 24628.270217002104 20878.27085891468 21917.19600127879 19242.032048806515 20922.919779487172 0.8830236220472442 0.9336579812800403 1.1207266519210908 1.1666513432506485 1.3177889364504445 1.1770952848152512 0.9978660282100652 1.047520911625652 0.9196628506730404 1.0 14.352796572312963 -11.525209535955018 3.316019214713069 0.9265488569709049 1.0721555284826751 0.01605166152448423 0.12921648354673937 0.12070118594834309 8.483979638841091e-05 0.21521882597362144 0.03375114195927511 2.983942595745296e-12 11.525209535955018 0.1456066715117702 TPVS(ph)PQVTDSK ddPTM_PC-9_Lapatinib_30min_R1 2 TPVSPQVTDSK 11 0 C9JM94;B5MCC4;E7EX78;O14901-2;O14901 C9JM94 KLF11 Krueppel-like factor 11 1 T(0.014)PVS(0.985)PQVT(0.001)DSK;T(0.018)PVS(0.982)PQVTDSK 135.94 7.651e-05 8607100.0 55389.0 46124.0 51301.0 42668.0 46335.0 44315.0 38100.0 40599.0 54594.0 34337.0 True False 54599.142702901445 46017.20271185012 47083.22980758671 45805.94705627545 43609.666398114976 42419.7507533105 40072.63157526826 42485.37775393627 48445.048819693526 40272.10469882345 1.3557558789445776 1.1426570092621584 1.1691276172353178 1.1374113024098707 1.0828752736975535 1.0533283788008674 0.9950468661857391 1.0549579683422277 1.2029430590229084 1.0 15.29749325186313 -1.5228787453163497 0.5820782093195372 1.0641764427743179 16.221355370337328 0.6580929470589303 0.06013156203303225 99.23588330631287 0.8180489118672035 0.028542374110977098 1902.2813942393147 0.02999999999751237 1.5228787453163497 15.15717892756301 TPVS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 1 TPVSPVK 7 0 P23443-3;P23443-5;P23443-2;P23443 P23443-3 RPS6KB1 Ribosomal protein S6 kinase beta-1 1 T(0.004)PVS(0.996)PVK 78.098 0.028827999999999996 56847000.0 388350.0 438790.0 419890.0 427150.0 384900.0 403380.0 457590.0 468100.0 406240.0 348980.0 True False 511837.22181819467 580620.2864938764 414321.984248748 328677.1669017133 331463.27885761496 378156.5848324889 498314.62353070924 395765.90086790087 427713.0170446031 336762.316421245 1.5198767702320772 1.7241248743745943 1.2303098180690921 0.9759915254014994 0.9842647549763209 1.1229183503995892 1.4797220449908763 1.1752083934856008 1.2700738657159931 1.0 18.3613711848309 -5.3453159827125 5.255788624365701 1.1549461274960882 1.6200373968250517 0.6068058281756021 0.15115718000772668 0.14445701045244796 6.670445550938722 0.042886728091111444 0.09273671954543414 4.515273039149074e-06 5.3453159827125 0.4650912693289635 TPVS(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TPVSPVK 7 0 P23443-3;P23443-5;P23443-2;P23443 P23443-3 RPS6KB1 Ribosomal protein S6 kinase beta-1 1 T(0.029)PVS(0.971)PVK;T(0.002)PVS(0.998)PVK;T(0.058)PVS(0.942)PVK 79.48899999999999 0.026793 110104700.0 532475.0 702980.0 557825.0 569866.0 657290.0 408017.0 574603.0 427506.0 412932.0 422005.0 True False 622612.5006393646 772767.2085670314 571125.6635630928 537938.2555504995 528498.7428957437 386619.87024712213 520172.44407453266 416284.42048004875 418970.3493094062 498511.16591025767 1.2489439419125223 1.550150250207526 1.1456627305834655 1.079089682110229 1.060154273436845 0.7755490682764801 1.0434519417929637 0.8350553587298957 0.8404432597700922 1.0 18.927266293649943 -5.777084115535151 1.1940057314430257 0.90407580912384 1.4116889759057252 0.7102802504550656 0.11634241182133719 0.257574560153589 0.721945567932568 0.04008412354908175 0.10429678595795502 1.6707669835128587e-06 5.777084115535151 0.5076131667818852 TPVS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 2 TPVSPVK 7 0 P23443-3;P23443-5;P23443-2;P23443 P23443-3 RPS6KB1 Ribosomal protein S6 kinase beta-1 1 T(0.021)PVS(0.979)PVK;T(0.012)PVS(0.988)PVK 70.399 0.044085 139128000.0 641370.0 1046340.0 822420.0 896740.0 919020.0 838090.0 842060.0 897090.0 780440.0 648190.0 True False 632223.9461871466 1043917.2640169399 754803.8022330079 962689.2510369456 864965.0504628373 802246.8443832111 885657.7465687756 938772.0763880552 692538.6288024621 760228.7778411171 0.8316232752757977 1.373161993395509 0.9928640222966632 1.2663151923435099 1.1377694132010474 1.0552702920052779 1.1649884513499333 1.234854696048158 0.9109608173070215 1.0 19.536074112715944 -8.271564612684369 24.850022945950293 0.9554803848918116 1.138697046551708 0.1926792301680772 0.14411252318812728 1062.744309904636 2608227.027949295 0.12079708142407329 0.03264897076577324 5.351005376222761e-09 8.271564612684369 0.18321666165989625 TPVS(ph)PVKFSPGDFWGR ddPTM_PC-9_Lapatinib_30min_R1 1 TPVSPVKFSPGDFWGR 16 1 P23443-3;P23443-5;P23443-2;P23443 P23443-3 RPS6KB1 Ribosomal protein S6 kinase beta-1 1 T(0.031)PVS(0.968)PVKFS(0.001)PGDFWGR 62.556000000000004 0.017444 12433000.0 57885.0 23870.0 30765.0 20066.0 17567.0 21910.0 14889.0 11227.0 26205.0 11108.0 True False 57059.54928519107 23814.730481568422 28235.620456334276 21541.72057821373 16533.74359805083 20972.960374704588 15659.879567563486 11748.647406178545 23253.516949116547 13028.002999520377 4.379761755296779 1.827964768080354 2.167302268611219 1.6534936765831867 1.2690927073519647 1.6098369316829835 1.202016883795621 0.9017995625738702 1.7848872885562446 1.0 13.66932833655684 -2.5205327980930115 0.9133774108248841 1.3473189823128746 199.9999999815805 0.8631568885981838 0.34958758698016296 41.20268300992105 0.6657865384311996 0.11228961454188982 16399.054276757422 0.0030162490762237915 2.5205327980930115 198.6526809992676 up TQAQVNS(ph)PIVTENK ddPTM_PC-9_AZD4547_30min_R2 2 TQAQVNSPIVTENK 14 0 A7KAX9;A7KAX9-2;G3V174 A7KAX9 ARHGAP32 Rho GTPase-activating protein 32 1 TQAQVNS(0.999)PIVTENK;T(0.367)QAQVNS(0.633)PIVTENK 183.31 7.4098e-06 16620500.0 80493.0 91871.0 96232.0 135650.0 141124.0 149615.0 115679.0 150482.0 123849.0 133546.0 True False 106088.09964159122 121566.50411467643 94955.9008031283 104377.98827160828 121531.36857755797 140259.55039841507 125974.20690008302 127228.46463235105 130395.40529725532 128870.5951882388 0.823214166789797 0.9433222833890583 0.7368313979184161 0.8099441778719603 0.9430496413866905 1.0883751269522783 0.9775248319143317 0.9872575233047607 1.011832102635898 1.0 16.975563591390532 -6.437242280605902 4.130282147644146 1.010764835649958 0.8312428171565773 0.7140245973155193 0.05496639835005244 0.131574287043887 4.081131402230971 0.01813949306577497 0.020346782317346476 3.653908935008048e-07 6.437242280605902 -0.17952201849338056 TQAQVNS(ph)PIVTENK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TQAQVNSPIVTENK 14 0 A7KAX9;A7KAX9-2;G3V174 A7KAX9 ARHGAP32 Rho GTPase-activating protein 32 1 T(0.039)QAQVNS(0.961)PIVTENK;T(0.242)QAQVNS(0.756)PIVT(0.002)ENK 170.09 0.00028148 8821300.0 39528.0 38012.0 35533.0 46493.0 58684.0 48193.0 57648.0 45338.0 55828.0 49978.0 True False 46219.30968641315 41785.58014744372 36380.24147965291 43888.147942339754 47185.29146661883 45665.67424107222 52187.16410462303 44147.925539581775 56644.37888380057 59038.61577436968 0.7828657410101111 0.7077669352401045 0.6162109494350068 0.7433803683688809 0.799227604640136 0.7734882270206778 0.8839496560025877 0.7477804985859379 0.9594462563329861 1.0 15.84937127576376 -7.957179065541467 0.43691011100880006 1.0090167999623796 0.6959469199604487 0.6798160330038063 0.062414290042373415 0.594520323822755 0.30440978277494013 0.07282516074549372 0.0518281098312324 1.1036234870555216e-08 7.957179065541467 -0.3130698800019309 TQAQVNS(ph)PIVTENK ddPTM_PC-9_Lapatinib_30min_R1 2 TQAQVNSPIVTENK 14 0 A7KAX9;A7KAX9-2;G3V174 A7KAX9 ARHGAP32 Rho GTPase-activating protein 32 1 TQAQVNS(1)PIVTENK;T(0.002)QAQVNS(0.998)PIVTENK 195.6 1.2677e-07 17164800.0 59287.0 76121.0 77109.0 66541.0 101164.0 95698.0 104213.0 92752.0 100497.0 87824.0 True False 58441.55650809579 75944.74650136044 70769.3956693477 71434.64711426888 95213.7324160765 91605.21962293386 109608.63922187478 97061.59652782317 89177.96957967436 103004.26138187593 0.5673702788997316 0.7372971320070382 0.6870530861531899 0.6935115708410695 0.9243669255884766 0.8893342701941088 1.0641175204928068 0.9423066116456965 0.865769710721557 1.0 16.65234449871255 -6.277959703019681 2.5819605105994916 0.9547942794166258 0.6691871013606326 0.8136868208606697 0.06491185935526853 0.12291051881891689 1.622958275936711 0.02143181685344153 0.026778037926002102 5.272787838888761e-07 6.277959703019681 -0.2856071780559931 TQASS(ph)SPAALKPPAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQASSSPAALKPPAGR 16 1 H7C1J4;Q6BDS2 H7C1J4 UHRF1BP1 UHRF1-binding protein 1 1 T(0.011)QAS(0.208)S(0.574)S(0.208)PAALKPPAGR 59.153999999999996 0.023896 3568900.0 24052.0 21972.0 21043.0 22999.0 26513.0 20995.0 20115.0 17726.0 18284.0 16643.0 True False 28123.528551346128 24153.23495211073 21544.74492602191 21710.44059376403 21317.96797516299 19893.985240414808 18209.5615800113 17260.711282249475 18551.368910070392 19660.244154084485 1.4304770750012972 1.228531790491158 1.0958533758364295 1.1042813315852749 1.0843185775357782 1.0118890225624062 0.9262123825775683 0.8779499962956209 0.9435980939339597 1.0 14.262993617692832 -1.5228787452803376 0.3675846826927265 0.9248509530396518 7.538245621803222 0.9092278047621911 0.04657118863919241 18.92047134874052 0.2620865673710987 0.0408578100685357 88.15866667787013 0.029999999999999995 1.5228787452803376 6.61339466876357 TQASSS(ph)FQDSSQPAGK ddPTM_PC-9_AZD4547_30min_R2 2 TQASSSFQDSSQPAGK 16 0 P46087-2;P46087;P46087-4 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 T(0.008)QAS(0.019)S(0.069)S(0.904)FQDSSQPAGK;TQASS(0.079)S(0.921)FQDSSQPAGK 250.38 1.8870999999999998e-47 13361500.0 39912.0 46411.0 47093.0 62451.0 56290.0 49679.0 35326.0 49173.0 36820.0 49273.0 True False 52603.18577882786 61412.44813342894 46468.51604998044 48053.88680833179 48475.10513612664 46572.564276595745 38469.94556447007 41574.44273312818 38766.230030480205 47547.967267533975 1.1063182887051748 1.2915893499270936 0.9772976369004404 1.0106401928383435 1.0194990011534253 0.979485916076075 0.8090765552187459 0.8743684561572298 0.8153078303507205 1.0 15.537096045015232 -5.798293092097018 0.659176844958194 0.8709776615380821 1.231622045715351 0.5948731492490448 0.08604437129781345 0.7680603082267369 0.570910952043679 0.04875505162287947 0.1756392331436337 1.5911345564573007e-06 5.798293092097018 0.36064438417726896 TQASSS(ph)FQDSSQPAGK ddPTM_PC-9_Lapatinib_30min_R1 2 TQASSSFQDSSQPAGK 16 0 P46087-2;P46087;P46087-4 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 TQASS(0.022)S(0.976)FQDS(0.002)SQPAGK;TQASS(0.023)S(0.94)FQDS(0.037)SQPAGK 266.29 5.202099999999999e-69 10542000.0 73556.0 63155.0 65641.0 59271.0 45882.0 54335.0 48371.0 50108.0 53779.0 38919.0 True False 72507.07795148174 63008.76847773163 60244.250361587554 63629.987062259825 43183.31096748268 52011.21871107138 50875.4136988793 52436.200608247425 47721.84270202401 45646.097293692226 1.5884617141518778 1.380375808961848 1.3198116363370374 1.393985265659344 0.9460460702617423 1.1394450302382968 1.114562179796907 1.1487553967838016 1.0454747619490052 1.0 15.478203895712342 -5.05169251719443 0.5544376937200656 1.058870101311215 1.801292719400778 0.767727512122763 0.09355159950007365 1.5456332745182162 0.4474705318733592 0.05589462010854396 0.7124383083690351 8.877843456236241e-06 5.05169251719443 0.742422618089563 TQASSS(ph)PAALKPPAGR ddPTM_PC-9_Lapatinib_30min_R1 1 TQASSSPAALKPPAGR 16 1 H7C1J4;Q6BDS2 H7C1J4 UHRF1BP1 UHRF1-binding protein 1 1 T(0.002)QAS(0.058)S(0.165)S(0.775)PAALKPPAGR 72.932 0.0072714 4255900.0 35470.0 26374.0 28968.0 27124.0 26537.0 25787.0 21433.0 18605.0 19632.0 18432.0 True False 34964.191295598655 26312.932623413726 26586.3628597137 29118.789443011516 24976.145833749353 24684.150122433013 22542.69586752557 19469.456220891756 17420.83742587507 21617.94664090381 1.617368748123474 1.21718001531313 1.2298283135461643 1.3469729538472996 1.1553431160058198 1.14183601858502 1.0427769224331427 0.9006154258912432 0.8058506996641719 1.0 14.399941876180305 -6.680483858798556 0.5814002355864436 0.8714142452388981 1.4227446879473098 0.7413763588426265 0.11172644271874092 0.4674444809806386 0.34455255321064215 0.09214424456043106 0.11611141423110981 2.0869696878106088e-07 6.680483858798556 0.5513304427084117 TQATGLTKPTLPPS(ph)PLMAAR ddPTM_PC-9_AZD4547_30min_R2 2 TQATGLTKPTLPPSPLMAAR 20 1 B1AHC3;B1AHC4;H0Y9T8;P85298-4;P85298-3;P85298 B1AHC3 PRR5-ARHGAP8;ARHGAP8 Rho GTPase-activating protein 8 1 TQATGLTKPTLPPS(1)PLMAAR;TQATGLTKPT(0.001)LPPS(0.999)PLMAAR 80.596 0.0019879000000000003 25828700.0 68381.0 90511.0 125815.0 210669.0 166239.0 146228.0 152253.0 165943.0 149653.0 149499.0 True False 90124.73558684162 119766.91071092595 124146.61089393926 162102.5168536045 143159.58434401438 137084.34004384227 165803.22204685718 140300.32234078652 157563.35205734542 144265.08551395402 0.6247161970324713 0.8301863911441103 0.8605450892824044 1.1236434392708632 0.9923370151135237 0.9502253407709158 1.1492955586320286 0.97251751413696 1.0921793828078044 1.0 17.13836266095563 -4.921784013857553 1.0797027877547296 1.0392054985172747 0.49282522645446775 0.7662662424482451 0.07205624616133632 0.6409863164233731 0.7229441238613716 0.02252828385343536 0.38084558146258474 1.1973358500750692e-05 4.921784013857553 -0.546380272062807 TQATGLTKPTLPPS(ph)PLMAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TQATGLTKPTLPPSPLMAAR 20 1 B1AHC3;B1AHC4;H0Y9T8;P85298-4;P85298-3;P85298 B1AHC3 PRR5-ARHGAP8;ARHGAP8 Rho GTPase-activating protein 8 1 TQATGLTKPTLPPS(1)PLMAAR;TQATGLTKPTLPPS(0.999)PLMAAR 81.312 0.0019414000000000002 45655000.0 66725.0 70643.0 79143.0 96506.0 95467.0 86369.0 89384.0 88044.0 83702.0 63310.0 True False 78020.2246211779 77655.97017667753 81030.06927149872 91099.08169667353 76760.92666559355 81839.65759606512 80916.90043588015 85732.93829032921 84925.98340137333 74787.60183831572 1.0432240465451856 1.0383535274277542 1.0834692820700238 1.218104063473272 1.0263857214133432 1.0942944496735614 1.0819560789075098 1.1463522854453383 1.1355623300366806 1.0 16.190511501949594 -5.374268900106334 4.801089075427961 1.1054489916833163 1.0414174410026449 0.1343960534496661 0.05786756223171979 0.38090689502528907 13.360892624572232 0.014957604953466774 0.032494886125013285 4.224069934955993e-06 5.374268900106334 -0.06403155068067146 TQATGLTKPTLPPS(ph)PLMAAR ddPTM_PC-9_Lapatinib_30min_R1 3 TQATGLTKPTLPPSPLMAAR 20 1 B1AHC3;B1AHC4;H0Y9T8;P85298-4;P85298-3;P85298 B1AHC3 PRR5-ARHGAP8;ARHGAP8 Rho GTPase-activating protein 8 1 TQATGLTKPT(0.002)LPPS(0.998)PLMAAR;TQATGLTKPTLPPS(1)PLMAAR;TQATGLT(0.001)KPT(0.001)LPPS(0.998)PLMAAR 72.158 0.0016135000000000001 35895000.0 149744.0 124694.0 138065.0 102942.0 114307.0 116617.0 108959.0 105788.0 124240.0 93785.0 True False 147608.6231003138 124405.27870417628 126713.82864631231 110512.69808444497 107583.68699620868 111629.56275750464 114600.36387951844 110703.2966780812 110246.78289480023 109995.6122893425 1.3419501017188813 1.1310021928595595 1.1519898476767663 1.0047009674689775 0.9780725317770924 1.014854687693033 1.041863047937432 1.006433751074335 1.0022834602238226 1.0 16.74708645041712 -3.425706513538176 0.679691997025515 1.004046759000459 3.1699427170201058 0.902331127577497 0.033426790295511016 4.79574791457302 0.39867979726524744 0.01404107790133071 12.144158886687777 0.00037522648622274814 3.425706513538176 2.1658959580196466 TQCIPYS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 TQCIPYSPK 9 0 E9PM59;Q9H5J8 E9PM59 TAF1D TATA box-binding protein-associated factor RNA polymerase I subunit D 1 TQCIPY(0.001)S(0.999)PK;T(0.003)QCIPYS(0.997)PK 76.32600000000001 0.024679 13815500.0 69960.0 86970.0 71682.0 76366.0 94319.0 87092.0 81449.0 79592.0 76798.0 77561.0 True False 68962.35757090726 86768.62630842086 65788.58266052189 81982.21038950807 88771.34185828875 83367.278181368 85666.03068698227 83290.13488488128 68148.2005212079 90967.31550646361 0.7581003922887798 0.9538439803937667 0.723211213766634 0.9012271048460574 0.975859750989147 0.9164530987555021 0.9417231915664845 0.9156050656344055 0.7491503969507123 1.0 16.473060658631326 -5.9709300392547995 24.997548029940614 0.9157837919893338 0.8236456900246111 0.2367652089793506 0.08395020913644156 329.598248081032 283422.7119218415 0.02287945540693507 0.03393521813483899 1.0692271077532607e-06 5.9709300392547995 -0.09213810196472272 TQDPS(ph)SPGTTPPQAR ddPTM_PC-9_AZD4547_30min_R2 1 TQDPSSPGTTPPQAR 15 0 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 TQDPS(0.935)S(0.065)PGTTPPQAR 199.33 5.846499999999999e-10 80380000.0 24712.0 22556.0 30508.0 40465.0 36746.0 27030.0 31195.0 37320.0 27476.0 37043.0 True False 32569.90195846847 29846.785893379238 30103.443986426922 31136.4194280179 31644.452182130222 25339.809827017125 33971.294567277466 31553.051528284686 28928.32526663428 35746.13584501169 0.9111446926651106 0.8349653798326373 0.8421454032667927 0.8710429446981172 0.8852551872833032 0.7088824911561246 0.9503487234136414 0.8826982492623145 0.809271396272366 1.0 15.125499674628012 -11.077492639641092 2.802990372753948 1.0081781492096946 0.8547824049357267 0.3310402610816643 0.06179997165249067 29447204.049140926 29688476.11050878 1806942.6289626565 0.015045222846245015 8.365797738664462e-12 11.077492639641092 -0.15339574427396796 TQDPS(ph)SPGTTPPQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQDPSSPGTTPPQAR 15 0 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 TQDPS(0.381)S(0.381)PGT(0.119)T(0.119)PPQAR 117.07 0.0019527000000000001 0.0 10127.0 9147.6 12992.0 10849.0 13590.0 15121.0 11703.0 12076.0 11696.0 8471.4 True False 11841.301082632719 10055.713273617703 13301.77855243438 10241.16570293257 10927.137056631282 14328.028141000828 10594.407117617322 11759.017795579639 11867.031873341895 10007.197760434492 1.1832784128090015 1.0048480617995805 1.3292211137293288 1.0233799659104488 1.091927762218706 1.4317722587285748 1.0586787001956215 1.1750560023977268 1.1858496411713415 1.0 13.288750423343156 -10.556958836934221 3.8784531253187424 0.9999714315211375 1.1637329300063552 0.13161808687791698 0.1270301290108706 86661113.10944393 206563123.03527972 36194.42936670928 0.030580577412514597 2.7735829764424554e-11 10.556958836934221 0.1637614984852177 TQDPS(ph)SPGTTPPQAR ddPTM_PC-9_Lapatinib_30min_R1 1 TQDPSSPGTTPPQAR 15 0 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 TQDPS(0.668)S(0.319)PGT(0.01)T(0.003)PPQAR 128.82 1.6884e-05 79681000.0 21589.0 20811.0 24610.0 21360.0 22544.0 22414.0 21420.0 21288.0 23356.0 17590.0 True False 21281.136901062288 20762.813408124017 22586.660797347206 22930.88565487118 21218.006243209307 21455.405469585956 22529.022791135067 22277.118195664796 20725.401330416564 20630.408062798277 1.0315422184710654 1.0064179702564633 1.0948237537810286 1.1115090688012728 1.0284821404706297 1.0399893886866616 1.092029916352477 1.0798195618745876 1.0046045268386903 1.0 14.332484737097316 -8.275794700008424 22.949216614514818 1.0023021923914162 1.0609031416535775 0.3438211779008279 0.0321995034681393 372.62719070138974 595686.1730828602 0.03253884233468547 0.008606486065047311 5.2991388595563204e-09 8.275794700008424 0.058600949262161306 TQDPSS(ph)PGTTPPQAR ddPTM_PC-9_AZD4547_30min_R2 1 TQDPSSPGTTPPQAR 15 0 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 TQDPS(0.044)S(0.486)PGT(0.424)T(0.047)PPQAR 165.24 0.00028577 98200000.0 23306.0 24130.0 37528.0 44836.0 35102.0 31914.0 28971.0 33694.0 28717.0 31166.0 True False 30716.823205085224 31929.550612131632 37030.3541996404 34499.75290929469 30228.693204624604 29918.41253493987 31549.362875736355 28487.366511093882 30234.921993082535 30074.887826192113 1.0213445643622334 1.0616681530670349 1.2312715649562889 1.1471282323204206 1.0051140798702678 0.9947971446425158 1.0490267846738277 0.9472143894842505 1.0053211891533989 1.0 14.876271735973306 -6.271961330374096 23.05064026891311 0.9997729310565411 1.1197983741230844 0.5015898012942801 0.05614083499630107 216.88785028803275 475139.02025733347 0.0186485962960763 0.02140253738424692 5.346119591823249e-07 6.271961330374096 0.12002544306654328 TQDPSS(ph)PGTTPPQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TQDPSSPGTTPPQAR 15 0 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 TQDPS(0.208)S(0.792)PGTTPPQAR;TQDPS(0.122)S(0.355)PGT(0.341)T(0.183)PPQAR 122.55 4.8378e-05 25916000.0 89307.0 102755.0 114764.0 118255.0 137954.0 123132.0 115070.0 126284.0 116519.0 94108.0 True False 104424.9112063472 112955.83731586298 117500.40900489358 111629.55573788304 110922.90401107495 116674.74115850232 104169.73656534454 122969.17880895843 118222.86994270874 111169.03544148189 0.9393345079558173 1.0160728377941324 1.0569526715624376 1.0041425230917251 0.9977859713414847 1.049525532853243 0.9370391328094081 1.1061459544073133 1.0634514320756152 1.0 16.762395476204404 -7.777456075310142 24.999932394702782 1.0635989931409575 1.0048861037409285 0.24506309904920243 0.044311456540595345 334.8447062452222 522640.80549661745 0.023305591283779827 0.011251821585249889 1.6693366359416084e-08 7.777456075310142 -0.058712889400029056 TQDPSS(ph)PGTTPPQAR ddPTM_PC-9_Lapatinib_30min_R1 2 TQDPSSPGTTPPQAR 15 0 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 TQDPS(0.131)S(0.426)PGT(0.406)T(0.037)PPQAR;TQDPS(0.185)S(0.765)PGT(0.05)TPPQAR 168.42 0.00020345 84903300.0 44569.0 40593.0 55200.0 42639.0 40909.0 45631.0 40181.0 43454.0 49837.0 42923.0 True False 43933.437887046406 40499.009402526506 50661.66907816195 45774.81429953428 38502.81305018851 43679.46850105635 42261.37557285704 45473.03147662621 44223.832253124274 50342.18335869762 0.8726963146197357 0.8044746314231819 1.0063462825437652 0.9092735206453012 0.7648220732869024 0.8676514522588707 0.8394823734945445 0.9032788894478855 0.8784647248614759 1.0 15.619480167610876 -9.176339542708607 1.1528826276186324 1.0001429035479876 0.869145519483861 0.2850573030317046 0.06118716075588779 4.768685377289751 7.1939227705757975 0.0625848710049092 0.018680627536852543 6.662856460986346e-10 9.176339542708607 -0.13099738406412664 TQDPSSPGT(ph)TPPQAR ddPTM_PC-9_AZD4547_30min_R2 1 TQDPSSPGTTPPQAR 15 0 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 TQDPSSPGT(0.5)T(0.5)PPQAR 151.11 0.00034966 7854700.0 26017.0 25341.0 26584.0 42318.0 40710.0 28677.0 26093.0 33254.0 25986.0 35866.0 True False 34289.86481278222 33531.98267973591 26231.478790322977 32562.238906582523 35058.11920575087 26883.82265665444 28415.226451161125 28115.35840089977 27359.56690852955 34610.34225676077 0.9907404139028431 0.968842851393236 0.757908679310992 0.9408239498186941 1.0129376631316793 0.776756914370096 0.8210039138116442 0.8123397969405439 0.7905026395162313 1.0 15.078915587729783 -6.7745035353582 24.996404525453617 0.8271970996120326 0.9267409104208714 0.21674371781704327 0.08718469439913523 351.3791826929637 672309.8571877865 0.030700822002761464 0.027236364165134835 1.680724243779379e-07 6.7745035353582 0.09954381080883878 TQDPSSPGT(ph)TPPQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQDPSSPGTTPPQAR 15 0 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 TQDPS(0.02)S(0.061)PGT(0.696)T(0.223)PPQAR 102.15 0.0037525999999999996 4664400.0 12042.0 14670.0 16586.0 14348.0 18819.0 20527.0 15728.0 19016.0 16092.0 14155.0 True False 14080.472759658649 16126.340649347561 16981.47314275528 13544.128076843625 15131.55204332185 19450.527984281744 14238.129979140831 18516.85014911746 16327.31505692697 16721.18944908165 0.842073633728967 0.9644254494247861 1.0155660991980404 0.8099978843064592 0.9049327554956264 1.163226338862514 0.8515022225241763 1.1073883353516119 0.9764445948445186 1.0 14.029389855631907 TQDPSSPGTT(ph)PPQAR ddPTM_PC-9_AZD4547_30min_R2 1 TQDPSSPGTTPPQAR 15 0 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 TQDPS(0.027)S(0.012)PGT(0.04)T(0.921)PPQAR 147.53 0.00030111 8583500.0 35657.0 23911.0 35848.0 52100.0 46566.0 39532.0 30569.0 41009.0 36460.0 36280.0 True False 46995.18428832593 31639.763144910034 35372.63209733288 40089.14993697596 40101.114687668734 37060.05779066373 33289.58178000017 34672.00134307146 38387.20116543474 35009.84824277255 1.3423418451414637 0.903738940126419 1.0103623372499257 1.1450820825894894 1.1454238364471412 1.0585609378730865 0.9508633556237276 0.9903499467533159 1.096468653598332 1.0 15.09547318767765 -7.0058998712994 23.60623985956529 1.0080585685389107 1.0952007720134362 0.14884378752408056 0.11018646732044511 288.46860077556005 1154210.6956912735 0.03951799226628031 0.03369331051185152 9.865069033685383e-08 7.0058998712994 0.0871422034745255 TQDPSSPGTT(ph)PPQAR ddPTM_PC-9_Lapatinib_30min_R1 2 TQDPSSPGTTPPQAR 15 0 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 TQDPSS(0.002)PGT(0.038)T(0.961)PPQAR;TQDPSS(0.002)PGT(0.029)T(0.969)PPQAR 172.26 0.00025352 14037700.0 48108.0 44910.0 54836.0 55083.0 58053.0 57293.0 52874.0 52370.0 67976.0 55147.0 True False 47421.971098073285 44806.01365426219 50327.59575308133 59133.98757150136 54638.43667658936 54842.711946506104 55611.55700553104 54803.30138608443 60319.827060986376 64679.08547124147 0.7331886459520012 0.692743463019193 0.7781123586767271 0.9142675277589438 0.8447620475537408 0.84792033695175 0.8598074107009109 0.8473110123125016 0.9326017308610003 1.0 15.981011659544816 -1.8299288731836627 0.1462654898838592 1.0100057074566406 2.7256991891326485e-17 0.7581647650110065 0.043121017771650054 35.633617392517436 0.3742327890539666 0.18440370597560987 7.466554667133044 0.014793506497912907 1.8299288731836627 -1.0100057074566406 TQEELRR ddPTM_PC-9_AZD4547_30min_R2 1 TQEELRR 7 1 P15924 P15924 DSP Desmoplakin 0 93.429 0.0088089 1518000.0 5404.4 4002.3 6499.4 10097.0 7380.6 7157.2 6921.3 6963.9 5112.8 8062.7 False True 7122.886781496724 5295.965205757749 6413.21370936748 7769.292647094934 6355.9310884295 6709.65915256851 7537.282291665251 5887.789269502187 5383.052170011926 7780.427327094885 0.9154878623043861 0.680677934914302 0.824275253755515 0.9985688858038458 0.8169128533975686 0.8623766883860624 0.9687491412479498 0.7567436879717782 0.6918710173239149 1.0 12.925633679687195 -11.937705455604569 2.338235769093773 2.522245709634327 0.8369204288595015 0.1921870295683511 0.10137527545629704 16722181.559331823 989245.2752539972 137772978.94707632 0.026986028963445614 1.1542358107705553e-12 11.937705455604569 -1.6853252807748258 TQEELRR ddPTM_PC-9_Lapatinib_30min_R1 1 TQEELRR 7 1 P15924 P15924 DSP Desmoplakin 0 78.77 0.01762 1469200.0 6289.6 7191.3 5347.5 6187.8 6485.7 5365.5 5954.4 4744.6 5116.1 3453.3 False True 6199.909150628622 7174.648986682156 4907.84919194694 6642.871453895687 6104.2238773768 5136.030072591391 6262.689696897039 4965.051437013868 4539.87094307862 4050.19830376699 1.5307668132847319 1.7714315321324368 1.211755283039418 1.6401348664131619 1.5071419766531953 1.2680934826856491 1.5462674237634895 1.225878602634344 1.1209009047424165 1.0 11.983776830895737 -8.008953106379385 0.5794749210594683 0.9766789206882893 1.552223963109312 0.574022317991702 0.15493096712652957 0.5548838246238189 0.4243309751305169 0.15111164569938537 0.08002178628897338 9.79595753069941e-09 8.008953106379385 0.5755450424210227 TQETLSQAGQK ddPTM_PC-9_Lapatinib_30min_R1 1 TQETLSQAGQK 11 0 A0A087WYR3;O43399;O43399-5;O43399-7;O43399-2;O43399-4;O43399-3;O43399-6 A0A087WYR3 TPD52L2 Tumor protein D54 0 193.3 0.00075508 5243500.0 12073.0 11746.0 13117.0 10716.0 12055.0 8495.7 12851.0 10576.0 12303.0 9248.5 False True 11900.836806082956 11718.80285867209 12038.57089308424 11504.090387528067 11345.948601041888 8132.358715443989 13516.361899574073 11067.399569586203 10917.306583666517 10847.09090214838 1.0971454847608837 1.080363662883203 1.1098432751863334 1.0605691877487227 1.0459899989217112 0.7497271654497972 1.246081739473301 1.0203103919221501 1.0064732269833039 1.0 13.405020555510845 -6.213120929202038 3.3803562370924816 1.0105656268734942 1.0913981603836576 0.10403043824892022 0.11201584577128598 0.6389373504330162 14.866250586140378 0.03526434419027511 0.045352809179349786 6.121799066310581e-07 6.213120929202038 0.0808325335101634 TQHIQQPR ddPTM_PC-9_AZD4547_30min_R2 3 TQHIQQPR 8 0 P51397 P51397 DAP Death-associated protein 1 0 ;; 101.25 0.0038966 6785400.0 24521.4 25155.5 30592.4 46605.0 35423.1 28651.600000000002 28997.300000000003 34076.0 28505.1 31910.9 False True 32318.69512319475 33286.52343238611 30186.724787280935 35860.93729007228 30505.214012214026 26860.01092266976 31578.003524786516 28810.337188580634 30011.82139168497 30793.709103922018 1.0495226480878364 1.080952064593823 0.9802886909598112 1.1645540057889576 0.9906313627002715 0.8722564349758294 1.025469306676168 0.9355916525466959 0.9746088491776568 1.0 14.910348030093953 -6.5083924113315375 24.946747098862847 0.958207080901476 1.0651486543086066 0.4458563764401614 0.0565821538736314 586.2478542674411 1009572.1595491114 0.01690502826948546 0.01847381060187229 3.101755697702571e-07 6.5083924113315375 0.10694157340713062 TQHIQQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TQHIQQPR 8 0 P51397 P51397 DAP Death-associated protein 1 0 ; 106.68 0.0032079 4097800.0 28423.0 28763.0 30922.0 35345.0 42231.0 35614.0 32510.0 31204.0 30504.0 34035.0 False True 33234.45252016094 31618.400551955245 31659.297752338054 33364.73424003607 33956.13870777007 33746.33914513615 29430.417447982483 30384.9280633709 30950.063292101673 40205.276079088246 0.8266191843773211 0.7864241620865465 0.7874413718751911 0.8298595978896882 0.8445692212378936 0.8393510115128511 0.7320038641219521 0.7557447933848376 0.7698010388293183 1.0 15.295097216119654 -11.902420642374361 2.393620188412152 2.646036030549214 0.7967893157579695 0.742440714583861 0.03589272624724242 4488365.915932674 426556.7918161801 40450448.567264415 0.00989675664810072 1.2519280140412396e-12 11.902420642374361 -1.8492467147912444 TQHIQQPR ddPTM_PC-9_Lapatinib_30min_R1 3 TQHIQQPR 8 0 P51397 P51397 DAP Death-associated protein 1 0 ;; 159.28 2.763e-05 5325700.0 29044.9 22212.9 25495.0 20447.199999999997 26634.0 23768.3 24092.3 23368.5 25235.2 22072.0 False True 28630.714399817665 22161.467394806503 23398.89951354601 21950.955297859637 25067.440484458708 22751.785215613465 25339.681409470733 24454.28582090345 22392.94603756329 25887.115790908698 1.1059831705883778 0.8560809776494835 0.9038820586480119 0.8479490521523683 0.9683365534781649 0.8788845153465752 0.9788530176223719 0.9446508455565975 0.865022825193507 1.0 14.659946616091267 -7.2708369609237415 24.812960737865897 0.9425192342619931 0.9208908002434769 0.011591033652783023 0.07662854735078746 3636.6675224576006 9602077.045105193 0.030858412733192 0.021135577152493208 5.359978394186477e-08 7.2708369609237415 -0.02162843401851622 TQKPNPAVPPPLS(ph)SSPLYSR ddPTM_PC-9_AZD4547_30min_R2 1 TQKPNPAVPPPLSSSPLYSR 20 1 O75140;H0Y770;A0A2R8Y6V4;A0A5F9UWT1;A0A2R8Y5T1;A0A2R8Y5K9;A0A2R8Y721;A0A2R8Y6H3;O75140-6;A0A2R8Y842;A0A2R8Y7U0;O75140-8;O75140-5;O75140-1;O75140-4;O75140-9;A0A2R8YEW8;H7C1T0 O75140 DEPDC5 DEP domain-containing protein 5 1 TQKPNPAVPPPLS(0.498)S(0.129)S(0.331)PLY(0.006)S(0.035)R 80.477 0.00067233 7234600.0 54863.0 57982.0 79311.0 102890.0 86651.0 77246.0 73664.0 86008.0 77570.0 77486.0 True False 72308.29277870906 76723.5476001914 78259.28431911324 79170.3001346536 74621.0043551345 72415.79540872228 80219.95329392298 72717.43986722165 81670.1918377063 74773.2387249027 0.9670343830462876 1.026082979800622 1.0466215674706296 1.0588052822738905 0.997964052749831 0.9684720983552195 1.0728431008460022 0.9725062215742117 1.092238255697043 1.0 16.1902344027774 -7.27297534500281 24.880696894407397 1.0321057375173004 1.0147461330470633 0.06467223384606735 0.042004102121565134 2781.3080547933146 5998685.913508577 0.017289597214014282 0.011757152915222049 5.3336517389121786e-08 7.27297534500281 -0.0173596044702371 TQKPNPAVPPPLS(ph)SSPLYSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQKPNPAVPPPLSSSPLYSR 20 1 O75140;H0Y770;A0A2R8Y6V4;A0A5F9UWT1;A0A2R8Y5T1;A0A2R8Y5K9;A0A2R8Y721;A0A2R8Y6H3;O75140-6;A0A2R8Y842;A0A2R8Y7U0;O75140-8;O75140-5;O75140-1;O75140-4;O75140-9;A0A2R8YEW8;H7C1T0 O75140 DEPDC5 DEP domain-containing protein 5 1 TQKPNPAVPPPLS(0.323)S(0.323)S(0.323)PLYS(0.032)R 68.97 0.0022889 7234800.0 13383.0 17017.0 19111.0 19082.0 25714.0 24362.0 18379.0 27332.0 22193.0 17909.0 True False 15648.477573701359 18706.33529856493 19566.678718871106 18012.897404678708 20675.526289493497 23084.413833150076 16638.008067562903 26614.563960647778 22517.53063996894 21155.759932433997 0.7396792941344831 0.8842194919165327 0.9248865926519301 0.8514417568646659 0.9773000996194775 1.0911644822438757 0.7864528677154771 1.258029210278798 1.064368791850734 1.0 14.368762888976295 -5.521831346864454 0.4174324269189002 1.080676413344914 0.6839719819072336 0.3944092380950418 0.11442080435606329 3.145458650955663 0.6760472768089097 0.09877013176250998 0.5871828539720626 3.007243903573363e-06 5.521831346864454 -0.3967044314376804 TQKPNPAVPPPLS(ph)SSPLYSR ddPTM_PC-9_Lapatinib_30min_R1 1 TQKPNPAVPPPLSSSPLYSR 20 1 O75140;H0Y770;A0A2R8Y6V4;A0A5F9UWT1;A0A2R8Y5T1;A0A2R8Y5K9;A0A2R8Y721;A0A2R8Y6H3;O75140-6;A0A2R8Y842;A0A2R8Y7U0;O75140-8;O75140-5;O75140-1;O75140-4;O75140-9;A0A2R8YEW8;H7C1T0 O75140 DEPDC5 DEP domain-containing protein 5 1 TQKPNPAVPPPLS(0.791)S(0.155)S(0.051)PLYS(0.004)R 119.69 6.0197e-06 5416100.0 42248.0 42833.0 45383.0 41983.0 49614.0 50163.0 41241.0 37253.0 48207.0 34078.0 True False 41645.53577266566 42733.8228201517 41651.78492344609 45070.569871182444 46695.802064876974 48017.64542566438 43376.257186237235 38983.91037876271 42777.42001778522 39968.33689391926 1.041963189091352 1.0691919189325383 1.0421195416260352 1.1276568747607667 1.168319867519462 1.2013921308036646 1.0852655015734831 0.9753698404372108 1.0702827123210457 1.0 15.286569922164858 -7.595526341741934 6.803628836058933 1.0183043987445615 1.1101337844824184 0.3839221940306159 0.052794378870033076 0.25767856968654185 19.527114313093005 0.02794463224825401 0.016003088662551478 2.5378950475494875e-08 7.595526341741934 0.09182938573785693 TQKPNPAVPPPLSS(ph)SPLYSR ddPTM_PC-9_AZD4547_30min_R2 1 TQKPNPAVPPPLSSSPLYSR 20 1 O75140;H0Y770;A0A2R8Y6V4;A0A5F9UWT1;A0A2R8Y5T1;A0A2R8Y5K9;A0A2R8Y721;A0A2R8Y6H3;O75140-6;A0A2R8Y842;A0A2R8Y7U0;O75140-8;O75140-5;O75140-1;O75140-4;O75140-9;A0A2R8YEW8;H7C1T0 O75140 DEPDC5 DEP domain-containing protein 5 1 TQKPNPAVPPPLS(0.16)S(0.411)S(0.411)PLY(0.001)S(0.018)R 76.351 0.0074596 0.0 26154.0 22336.0 32307.0 40844.0 43486.0 31475.0 29977.0 35998.0 28761.0 38486.0 True False 34470.42796300521 29555.675195713728 31878.588070981215 31428.04683350951 37448.71952299883 29506.863274338295 32644.894926856126 30435.33625174684 30281.24774325477 37138.61685422671 0.9281559434026732 0.7958205689706515 0.8583676714754428 0.8462363301484318 1.0083498712402055 0.7945062518121255 0.8790013654787158 0.8195064552675452 0.815357444842712 1.0 15.180632465832323 TQLAS(ph)WSDPTEETGPVAGILDTETLEK ddPTM_PC-9_AZD4547_30min_R2 3 TQLASWSDPTEETGPVAGILDTETLEK 27 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 T(0.047)QLAS(0.802)WS(0.15)DPT(0.002)EETGPVAGILDTETLEK;T(0.05)QLAS(0.661)WS(0.203)DPT(0.037)EET(0.048)GPVAGILDTETLEK;T(0.037)QLAS(0.607)WS(0.355)DPT(0.002)EETGPVAGILDTETLEK 128.63 1.9084e-12 8127200.0 29315.4 23405.800000000003 29451.6 46244.3 36955.9 35502.0 31683.0 35435.8 32718.9 32208.9 True False 38637.08740180021 30971.267124634487 29061.05254066643 35583.391102312824 31825.211190267957 33282.05432773812 34502.72562189619 29960.01134367605 34448.35425704177 31081.276214626167 1.243098485885803 0.9964605993257152 0.9350019072573004 1.144849743511113 1.0239351489464166 1.070807199096809 1.110080724602292 0.9639247480313413 1.108331396020062 1.0 14.923758122378459 TQLAS(ph)WSDPTEETGPVAGILDTETLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQLASWSDPTEETGPVAGILDTETLEK 27 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 T(0.125)QLAS(0.566)WS(0.258)DPT(0.038)EET(0.013)GPVAGILDTETLEK 73.817 3.8882e-05 1361000.0 994.64 623.28 1038.4 2216.6 2817.7 4210.9 5302.5 3832.1 5143.8 4980.2 True False 1163.0129069645313 685.1551192859812 1063.1593941539306 2092.4110883141593 2265.5919120286944 3990.072991134208 4800.208813224456 3731.5114354455714 5219.018343886462 5883.07083675849 0.19768806788757606 0.11646215697506278 0.18071504213600803 0.35566647867647566 0.3851036261322686 0.6782296358227595 0.8159359195935367 0.6342795351248217 0.8871248517486977 1.0 12.522353692190702 -6.669108703938949 0.5866405311836385 0.9238593847748013 0.07767850221365878 0.9261878431242381 0.08229994329836106 0.2248135906462359 0.16898017943874338 0.0682383633188534 0.08638227767179006 2.1423543025745176e-07 6.669108703938949 -0.8461808825611425 down TQLAS(ph)WSDPTEETGPVAGILDTETLEK ddPTM_PC-9_Lapatinib_30min_R1 2 TQLASWSDPTEETGPVAGILDTETLEK 27 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 T(0.038)QLAS(0.607)WS(0.355)DPT(0.001)EETGPVAGILDTETLEK;T(0.012)QLAS(0.976)WS(0.012)DPTEETGPVAGILDTETLEK 141.23 1.3494e-10 4489900.0 10544.599999999999 10713.5 14259.0 16017.8 24192.6 30667.1 39741.0 42051.0 41309.0 40413.4 True False 10394.23207035718 10688.693548985479 13086.680061331728 17195.802445814406 22769.638832481625 29355.539621501728 41798.5945257936 44004.84297472286 36656.34541694544 47398.802342529416 0.21929313730846678 0.22550556175962402 0.2760972728120911 0.3627898089396484 0.4803842651537033 0.6193308305421453 0.8818491704438925 0.9283956724627772 0.7733601611291112 1.0 15.532562985586006 -6.752487608503192 0.9258608067409535 0.9275736093652754 0.22242000260696765 0.9587278891327615 0.058632588841197944 0.10151411673534941 0.18832857586243149 0.035428039063764495 0.0329645179858002 1.7681226659318394e-07 6.752487608503192 -0.7051536067583077 down TQLASWS(ph)DPTEETGPVAGILDTETLEK ddPTM_PC-9_Lapatinib_30min_R1 1 TQLASWSDPTEETGPVAGILDTETLEK 27 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 T(0.016)QLAS(0.289)WS(0.693)DPT(0.001)EETGPVAGILDTETLEK 126.31 4.9391999999999995e-11 2788600.0 10708.0 8620.8 12183.0 11312.0 19678.0 26981.0 26938.0 27740.0 30687.0 25618.0 True False 10555.30195639329 8600.839067260373 11181.36076773998 12143.92221572579 18520.578728436518 25827.08552578293 28332.7178313537 29028.901669848805 27230.7069115642 30046.037166160684 0.35130429673704816 0.28625535606229824 0.3721409484353888 0.40417716814258847 0.6164067036865447 0.8595837575169699 0.9429768616296392 0.9661474326651827 0.9062994484421644 1.0 14.874887103007197 -6.551075393514288 1.4302928953753231 0.9590080520235651 0.32594652684951136 0.9892750865216718 0.028811176284650495 0.035765405223194435 0.15083046973101985 0.011792957488977084 0.012775831597488681 2.811412726833706e-07 6.551075393514288 -0.6330615251740537 down TQLEELEDELQATEDAK ddPTM_PC-9_AZD4547_30min_R2 1 TQLEELEDELQATEDAK 17 0 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580;P35749-4;P35749-3;P35749;P35749-2 P35579;P35749-4 MYH9;MYH10;MYH11 Myosin-9;Myosin-10;Myosin-11 0 142.91 0.00018353 1474700.0 10567.0 11190.0 10781.0 10705.0 12682.0 14184.0 15097.0 14447.0 13216.0 11959.0 False True 13927.086192745897 14806.948667623414 10638.036895819736 8237.127640601297 10921.32320725455 13297.072237751056 16440.603753235704 12214.548109033469 13914.570779001262 11540.319050036302 1.2068198576106168 1.2830623315892498 0.9218147998937926 0.7137694898110625 0.9463623284505462 1.1522274367023873 1.4246229832947286 1.058423779799662 1.2057353630060594 1.0 13.49439548962837 -6.877440707618497 6.095726880447691 1.1918005091507942 1.0082313901332578 0.15130815067760628 0.17951451136640303 0.4037805569290412 20.016694209794615 0.0699577451881737 0.06173048862688402 1.3260481451253866e-07 6.877440707618497 -0.18356911901753636 TQLEELEDELQATEDAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQLEELEDELQATEDAK 17 0 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580;P35749-4;P35749-3;P35749;P35749-2 P35579;P35749-4 MYH9;MYH10;MYH11 Myosin-9;Myosin-10;Myosin-11 0 174.62 2.7910999999999998e-05 1189400.0 10084.0 14809.0 10757.0 9098.1 12959.0 9510.8 12590.0 10767.0 9826.6 9036.8 False True 11791.022031921428 16279.139650728552 11013.48767614967 8588.362953438178 10419.776976959876 9012.036905193487 11397.384056293426 10484.377658579497 9970.295434899235 10675.100304730555 1.1045350109447087 1.524963624324413 1.0316987533380986 0.8045229279609053 0.9760823485979299 0.8442109814368582 1.0676606056097475 0.9821338778365819 0.9339767449755022 1.0 13.381962005222615 -5.44500900254816 6.750114108988146 0.9435351542150259 1.3110254323676387 0.6056685976930353 0.11790749151515509 0.1454023588725916 10.569037649311964 0.028960276794104053 0.06058140598211828 3.5891449458152992e-06 5.44500900254816 0.3674902781526128 TQLEELEDELQATEDAK ddPTM_PC-9_Lapatinib_30min_R1 4 TQLEELEDELQATEDAK 17 0 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580;P35749-4;P35749-3;P35749;P35749-2 P35579;P35749-4 MYH9;MYH10;MYH11 Myosin-9;Myosin-10;Myosin-11 0 ;;; 229.54 1.1817e-28 9811100.0 27869.6 30246.800000000003 29143.7 26985.800000000003 30022.7 25416.4 33559.6 27840.300000000003 28591.8 31220.0 False True 27472.174393341298 30176.76539295787 26747.617483935304 28970.425753989824 28256.823812899227 24329.399820522194 35297.15187961606 29133.861974011983 25371.490398998307 36616.33540196492 0.7502709949468913 0.8241339571992918 0.730483189819699 0.7911885620436829 0.7716999394587941 0.6644411450091923 0.963972814104219 0.7956520403854667 0.6929008629748572 1.0 15.160199791603265 -7.252133502420664 24.977894822494854 0.8461024362474214 0.7597345075890886 0.2521049203930332 0.088825504916198 1156.3437322713153 3103746.129723102 0.033712326060720006 0.025754622919716304 5.595855580701927e-08 7.252133502420664 -0.08636792865833287 TQLGEDHEK ddPTM_PC-9_AZD4547_30min_R2 1 TQLGEDHEK 9 0 K7EIG1;I3L2B0;A0A494C0R8;O75153 K7EIG1 CLUH Clustered mitochondria protein homolog 0 96.113 0.0043719 1534100.0 14904.0 15274.0 27633.0 41440.0 28508.0 23401.0 18082.0 31350.0 22473.0 21290.0 False True 19643.161977541862 20211.021800650586 27266.568364918545 31886.64824161774 24550.15628389943 21937.731770700233 19691.262970524484 26505.577851332382 23660.876900461197 20544.64358017166 0.956120844875603 0.9837611308164496 1.3271862448484841 1.5520662657001572 1.1949662785872628 1.0678078539105487 0.9584621360639809 1.2901454215011947 1.1516810602300795 1.0 14.326474681601422 -6.663530257723782 6.524620607503211 1.1037684132998176 1.218560970367538 0.08220999143302876 0.17816293485434645 0.6580771483329138 37.39791156329603 0.06596258666533453 0.06574569047472967 2.17005000878262e-07 6.663530257723782 0.1147925570677204 TQLGEDHEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TQLGEDHEK 9 0 K7EIG1;I3L2B0;A0A494C0R8;O75153 K7EIG1 CLUH Clustered mitochondria protein homolog 0 ; 104.43 0.0015507 0.0 12727.599999999999 13862.5 16000.7 17078.3 17889.0 20610.4 15949.0 17385.8 18448.9 16277.0 False True 14882.131298441416 15238.67738592914 16382.21737099267 16121.45821959565 14383.778867260997 19529.55434146442 14438.195259239397 16929.441171777777 18718.68026061025 19227.89125133889 0.7739866584384355 0.792529830064856 0.8520028097127881 0.8384413042939938 0.7480684532298577 1.0156888285970789 0.750898529147549 0.8804627065174885 0.9735170651803441 1.0 14.230912928599839 -8.240220752883205 0.19863597670313204 1.0631946110533448 0.7411772929947924 0.41122335035066215 0.07439002676063024 3.327345206391019 0.631627008119955 0.43747819169265434 0.351597017595268 5.751475142205547e-09 8.240220752883205 -0.3220173180585524 TQLGEDHEK ddPTM_PC-9_Lapatinib_30min_R1 2 TQLGEDHEK 9 0 K7EIG1;I3L2B0;A0A494C0R8;O75153 K7EIG1 CLUH Clustered mitochondria protein homolog 0 ; 103.91 0.0022983 4721400.0 30372.0 28841.0 30205.0 29008.0 36838.0 29800.0 34319.0 26872.0 31237.0 32070.0 False True 29938.889710457348 28774.220436485768 27721.661494671764 31141.34508785128 34671.26126629457 28525.52346719289 36095.86989584334 28120.57122105901 27718.760119807426 37613.2567694111 0.7959664299743671 0.7650021005329787 0.7370183779782756 0.8279353547810014 0.9217830159947994 0.7583901506341033 0.9596581895880452 0.7476239399702289 0.7369412409496444 1.0 15.198953608067002 -12.020178552074983 2.2803418858955324 3.615906699591312 0.807893164239781 0.38383670601340014 0.07384270080814954 2225267.8601687816 410976.5178829272 29951825.39192816 0.01935729118326813 9.546000393336082e-13 12.020178552074983 -2.808013535351531 TQLS(ph)PSIK ddPTM_PC-9_AZD4547_30min_R2 2 TQLSPSIK 8 0 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 T(0.016)QLS(0.666)PS(0.317)IK;T(0.004)QLS(0.971)PS(0.025)IK 98.75399999999999 0.0054093000000000006 25767100.0 104871.0 118378.0 105677.0 124713.0 118686.0 125895.0 118603.0 138139.0 120720.0 119922.0 True False 138217.79654769154 156641.37349203968 104275.6539318748 95962.34464664267 102208.49756948516 118022.76574814343 129158.43723554476 116792.79166842776 127101.01274523548 115723.56728141592 1.1943789825591384 1.3535823097392088 0.9010753503501827 0.8292376989492726 0.8832124689082139 1.0198680227436847 1.1160945023536821 1.009239469644171 1.09831571676452 1.0 16.820323175854334 -5.261566560160679 24.99999855680643 0.9795993490097965 1.273980659106646 0.6119727062819657 0.09294016563199618 7.681270260338937 1510281.5363795091 0.026900991171954644 0.062419569824503904 5.475621749143456e-06 5.261566560160679 0.29438131009684954 TQLS(ph)PSIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQLSPSIK 8 0 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 T(0.247)QLS(0.733)PS(0.02)IK 109.16 0.0037825000000000003 17908000.0 52825.0 61815.0 64048.0 58102.0 76056.0 41660.0 59501.0 45907.0 41816.0 45172.0 True False 61767.22915869197 67951.5846788971 65575.14722339257 54846.73330922554 61153.37277256431 39475.27626176146 53864.63453006478 44701.989892487116 42427.47989190023 53361.326018644766 1.1575280032791937 1.2734238398639945 1.2288890122498122 1.0278367762087053 1.1460242339404563 0.739773150464225 1.0094320840386193 0.8377226210021088 0.795097930607568 1.0 15.703506897210504 -6.334707638702399 1.2778831314589236 0.874740299639832 1.2223542565231214 0.6389594966877523 0.10502893967304201 0.26277520020896716 0.877629981034134 0.04108367320676521 0.05490622270586555 4.626923949780691e-07 6.334707638702399 0.34761395688328933 TQLS(ph)PSIK ddPTM_PC-9_Lapatinib_30min_R1 2 TQLSPSIK 8 0 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 T(0.271)QLS(0.678)PS(0.05)IK;T(0.207)QLS(0.67)PS(0.123)IK 86.014 0.012794 24423500.0 83159.0 156731.0 140586.0 149901.0 165904.0 143982.0 155708.0 154773.0 142578.0 153550.0 True False 81973.13741050701 156368.09899902358 129027.56175765346 160925.21959507663 156145.85289981382 137824.22549843523 163769.7983549049 161964.31860661524 126519.36422709952 180090.91290748623 0.4551764222141353 0.8682731209172714 0.7164579249144885 0.8935776769466701 0.8670390436636127 0.765303608457115 0.90937291455141 0.8993475350409117 0.7025305285230758 1.0 17.458365861488595 -4.75899364432359 24.99835374897626 0.8411501977424777 0.4551759166985019 0.6387022999426228 0.08828666671474346 40.320567869743165 412037.0207730777 0.02063459091402379 0.13541066289324277 1.741832364026015e-05 4.75899364432359 -0.3859742810439758 TQLS(ph)PSIKR ddPTM_PC-9_AZD4547_30min_R2 2 TQLSPSIKR 9 1 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 T(0.028)QLS(0.651)PS(0.322)IKR;TQLS(0.698)PS(0.302)IKR 102.53 0.0046234 71329000.0 112937.0 111265.0 142510.0 186524.0 163829.0 147144.0 134155.0 164974.0 126261.0 143168.0 True False 148848.61676446884 147229.23534433582 140620.2242856201 143523.7735670729 141084.1712443864 137943.06241903827 146094.53510732812 139481.05902538172 132934.89869305963 138155.73189694746 1.0773973306840239 1.065675910241324 1.0178385098818117 1.0388550051193646 1.0211966547260112 0.9984606539664397 1.0574627132828796 1.009592994154038 0.962210520459751 1.0 17.07593589332088 -1.522878745310466 0.2671550681324767 0.9956664109794844 1.5802002591847366 0.5571047416559182 0.022292499684520323 41.53786238811314 0.5782571303007423 0.02720803523844185 11.154979663742514 0.029999999997918803 1.522878745310466 0.5845338482052522 TQLS(ph)QAEVHK ddPTM_PC-9_AZD4547_30min_R2 3 TQLSQAEVHK 10 0 K7EMZ9;A0A140TA76 K7EMZ9 LSM14A 1 T(0.321)QLS(0.679)QAEVHK;T(0.042)QLS(0.958)QAEVHK;T(0.001)QLS(0.999)QAEVHK 96.745 0.0054126 20639800.0 80462.0 67383.0 104124.0 143815.0 117898.0 117086.0 140106.0 167475.0 150403.0 149113.0 True False 106047.24228643114 89163.2370036165 102743.24772658692 110660.67366960076 101529.89776761521 109764.59391069677 152575.16257871382 141595.58694264444 158352.99552619003 143892.59925646472 0.7369888572060576 0.6196513056567823 0.7140273249457681 0.7690504879432085 0.705594994407287 0.7628230671895749 1.0603405829564165 0.9840366194947509 1.1004943711104422 1.0 17.13463286713653 -7.193346969441796 4.058998100369181 1.0362393171619997 0.7100260749639742 0.9171211853589815 0.04700245952462875 0.06076191055137441 1.9713685204446956 0.01918917099672476 0.014323709573781759 6.40697501739318e-08 7.193346969441796 -0.3262132421980255 TQLS(ph)QAEVHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQLSQAEVHK 10 0 K7EMZ9;A0A140TA76 K7EMZ9 LSM14A 1 T(0.195)QLS(0.805)QAEVHK 86.539 0.0063481 8290300.0 33234.0 33843.0 24844.0 26678.0 45464.0 34606.0 35301.0 61830.0 43292.0 30444.0 True False 38859.8597985796 37202.70937940485 25436.375181394666 25183.318151242966 36555.65556605476 32791.20043961872 31957.033722892316 60207.02801430021 43925.063599582536 35963.25620542858 1.0805434184436775 1.0344644313322544 0.7072878783861373 0.7002513345118508 1.0164723504802315 0.9117973148012374 0.88860234291211 1.6741261600558872 1.221387277855895 1.0 15.134236031623892 -7.72760463758045 24.99842992733984 1.3358175852534748 0.899558623824899 0.45566791237897386 0.1954240797096784 140.40287497374152 103735.1452704946 0.09107105283304891 0.05257614520538948 1.8723859017502216e-08 7.72760463758045 -0.4362589614285758 TQLS(ph)QAEVHK ddPTM_PC-9_Lapatinib_30min_R1 2 TQLSQAEVHK 10 0 K7EMZ9;A0A140TA76 K7EMZ9 LSM14A 1 T(0.066)QLS(0.934)QAEVHK;T(0.005)QLS(0.995)QAEVHK 113.65 0.0012767000000000002 15045900.0 99770.0 83385.0 102050.0 83530.0 136198.0 96602.0 121886.0 86820.0 118252.0 125860.0 True False 98347.26150442258 83191.9271556593 93659.84292439159 89673.07484791131 128187.10141557056 92470.55765026077 128196.66068722164 90853.97415199244 104933.21451123574 147614.73330209142 0.6662428560105604 0.5635746872597617 0.6344884472521999 0.6074805193354017 0.8683896149663971 0.626431763156196 0.8684543732153688 0.6154803935868725 0.7108586803221832 1.0 17.171477197197405 -14.52287874527837 0.1367897173963763 2.0442143411322453 0.5694616954127698 0.5137069397242044 0.09597171407873208 116.57421260847386 0.9828304717838215 33.42412064280428 0.6271283212738611 3.000000000013597e-15 14.52287874527837 -1.4747526457194755 TQLSPS(ph)IK ddPTM_PC-9_AZD4547_30min_R2 1 TQLSPSIK 8 0 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 T(0.001)QLS(0.122)PS(0.877)IK 73.84100000000001 0.028852 8950600.0 52587.0 51654.0 59110.0 55842.0 53382.0 63291.0 52596.0 69944.0 53655.0 56574.0 True False 69308.57212244988 68350.14535097573 58326.162778212085 42968.48965029962 45970.83074039283 59333.40376477026 57276.94210804697 59135.76195322464 56491.09376114654 54593.36147978543 1.2695421246063614 1.2519863862254406 1.0683746374512735 0.7870643698356948 0.8420589883884451 1.086824517789401 1.04915580494627 1.0832042642239779 1.0347612279207938 1.0 15.73643791050283 -5.344259874557483 3.8074594705644245 0.9847921940095862 1.2641002519276476 0.5741878490157619 0.09384553648718598 0.17657290480630516 4.782939863550582 0.028501783681188962 0.06678359299749767 4.526266546299597e-06 5.344259874557483 0.27930805791806146 TQLSPS(ph)IK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQLSPSIK 8 0 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 T(0.001)QLS(0.113)PS(0.886)IK 87.29799999999999 0.01183 16978000.0 59275.0 92214.0 64437.0 51146.0 67571.0 55356.0 51432.0 52734.0 47079.0 42906.0 True False 69309.08676538493 101368.39649890485 65973.42245868345 48280.45543756929 54330.94761248219 52453.033911331426 46559.988624565834 51349.788376291566 47767.441310282404 50684.51815629085 1.3674607017405855 1.9999873765461307 1.3016484097816163 0.9525681054852216 1.0719436543708911 1.0348926224293418 0.9186234834272942 1.013125708681876 0.9424463928607678 1.0 15.6292575155344 -5.517694613095004 4.362372586092641 0.9975001565333868 1.6856648405864398 0.7749232603126187 0.14911367372357742 0.07740622504237872 3.6271515384050157 0.03742566939095603 0.07425629770259555 3.0360253040263013e-06 5.517694613095004 0.6881646840530531 TQLWAS(ph)EPGTPPLPTSLPSQNPILK ddPTM_PC-9_AZD4547_30min_R2 1 TQLWASEPGTPPLPTSLPSQNPILK 25 0 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;H7C3A1 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 1 T(0.002)QLWAS(0.653)EPGT(0.345)PPLPTSLPSQNPILK 132.48 1.6433e-07 195030000.0 380020.0 286210.0 534150.0 589910.0 454640.0 492910.0 425790.0 520850.0 419660.0 454920.0 True False 500858.4550929574 378721.78535839985 527066.8219925906 453915.36351864657 391521.08365764143 462088.25977932 463684.48513547215 440364.60044231225 441842.37084712967 438993.3892668705 1.1409248233314015 0.8627049851271663 1.2006258747376692 1.0339913415933122 0.8918610011679015 1.0526086977095908 1.0562448011115528 1.0031235349072833 1.0064898051996114 1.0 18.743839689040925 -6.003534995116716 24.99197358325315 1.0031278569925386 1.0591740869853536 0.09442815647803349 0.09108406111716308 423.1816136933701 2991901.773107782 0.025221680606763792 0.03655231366482419 9.918934100075407e-07 6.003534995116716 0.056046229992815055 TQLWASEPGT(ph)PPLPTSLPSQNPILK ddPTM_PC-9_AZD4547_30min_R2 2 TQLWASEPGTPPLPTSLPSQNPILK 25 0 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;H7C3A1 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 1 T(0.002)QLWAS(0.038)EPGT(0.96)PPLPTSLPSQNPILK;T(0.015)QLWAS(0.337)EPGT(0.648)PPLPTSLPSQNPILK 95.223 9.4089e-06 242390000.0 20883.4 23341.9 32104.8 51749.0 39347.9 37572.3 32113.3 39873.0 30863.6 35940.6 True False 27523.8867982956 30886.71269926711 31679.069375096326 39819.06756408001 33885.123279193416 35222.898141458965 34971.321488294634 33711.54404038839 32494.986886711795 34682.33053346724 0.7935996911088777 0.8905604734221222 0.9134065931505706 1.1481081851075723 0.9770140229329587 1.0155862538554061 1.0083325125613611 0.9720091909007651 0.936932045421667 1.0 15.081913225517141 -5.25192121778495 2.2285691985268876 1.0057336186499317 0.8163338430064156 0.574645629198802 0.05750753096452346 0.24046685880760776 2.207611592023782 0.016026249326495042 0.059292961118190726 5.5985915227609215e-06 5.25192121778495 -0.18939977564351607 TQLWASEPGT(ph)PPLPTSLPSQNPILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TQLWASEPGTPPLPTSLPSQNPILK 25 0 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;H7C3A1 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 1 T(0.023)QLWAS(0.379)EPGT(0.598)PPLPTSLPSQNPILK;T(0.003)QLWAS(0.158)EPGT(0.839)PPLPTSLPSQNPILK 128.51 1.9882e-08 435870000.0 33625.2 31332.2 29680.4 44525.0 48198.0 40279.0 47576.0 38911.0 36365.3 35678.5 True False 39317.282232027435 34442.65374870399 30388.093299543838 42030.408601997646 38753.94789223797 38166.698332873006 43069.25685958825 37889.627479612376 36897.07371611152 42146.72961914938 0.9328667393012533 0.8172082166264915 0.7210071475091865 0.9972400938767291 0.9195007119752917 0.9055672570033039 1.0218884655766913 0.8989932984597983 0.8754433392465953 1.0 15.363133068954447 -5.775832712419123 24.99999981721454 0.9417437163503632 0.8230454197882198 0.4170117578243987 0.06590166724607295 226.4015076856669 393239.6684580736 0.018697934260696835 0.027875291106081574 1.675588178063554e-06 5.775832712419123 -0.11869829656214348 TQMAEVLPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 TQMAEVLPSPR 11 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 TQMAEVLPS(1)PR;TQMAEVLPS(1)PR 128.73 0.00029525 80936000.0 102638.0 87917.0 115351.0 151110.0 108001.0 111635.0 98086.0 128271.0 86921.0 108636.0 True False 135274.748996977 116334.45093936066 113821.37037099541 116273.92412622726 93006.9253829601 104654.445802407 106815.46398223995 108449.66432434627 91515.4666072614 104832.68670622486 1.290387123016895 1.109715438900917 1.0857431393507995 1.1091380730522002 0.8871939497610666 0.9982997583156735 1.0189137313781862 1.0345023840537193 0.8729669102511641 1.0 16.677729092041844 -1.522878745282293 0.4926947647890739 0.97085014741948 10.452501256115022 0.7077641049362455 0.06151442213791978 58.08138885760115 0.6295813125161032 0.034627532839176654 567.8567751469051 0.029999999999864926 1.522878745282293 9.481651108695543 TQMAEVLPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TQMAEVLPSPR 11 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 TQMAEVLPS(1)PR;TQMAEVLPS(1)PR;TQMAEVLPS(1)PR 77.64399999999999 0.016972 44104800.0 118484.0 116588.0 122683.0 119318.0 139527.0 126398.0 121030.0 112504.0 116223.0 84261.0 True False 138541.00103432918 128162.08613675064 125608.22799786864 112632.99929417526 112187.68595295008 119769.46636903791 109565.16221868119 109550.8892078411 117922.54150268578 99536.85229029096 1.3918563612026413 1.2875842784637852 1.2619268653537754 1.1315708373587148 1.1270969833942912 1.203267569881959 1.1007497193013849 1.1006063250658664 1.1847123832967361 1.0 16.60294314413128 -1.5228787452803376 0.3298069574205716 1.0866626642045187 4.2754831249561915 0.7811264830108927 0.049918655444450656 26.68264005099537 0.3798674421967615 0.044842984634115686 51.852620649538984 0.029999999999999995 1.5228787452803376 3.188820460751673 TQMAEVLPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 TQMAEVLPSPR 11 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 TQMAEVLPS(1)PR;TQMAEVLPS(1)PR;TQMAEVLPS(1)PR;TQMAEVLPS(1)PR 151.3 6.7623e-05 73317800.0 340119.0 259592.0 334218.0 274237.0 255249.0 262333.0 243181.0 223893.0 300653.0 191414.0 True False 335268.8406898142 258990.93067328437 306739.886158788 294405.3038078145 240235.7556588422 251113.62911809125 255771.7222862283 234295.8861415808 266790.29312355426 224499.65485687758 1.4934047043571355 1.1536362086542875 1.3663267605214806 1.3113842156929059 1.0700940979708706 1.1185479517916432 1.139296728314737 1.043635841181798 1.1883772974779747 1.0 17.776353701422593 -1.5228787573860663 0.22154981578048044 1.0216745386385757 3.138019160679394 0.6033898757485086 0.09314578652458735 36.34953897965957 0.4665014404694546 0.14344606676851415 27.563965763391444 0.0299999991637659 1.5228787573860663 2.1163446220408186 TQPDGTSVPGEPAS(ph)PISQR ddPTM_PC-9_AZD4547_30min_R2 7 TQPDGTSVPGEPASPISQR 19 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 TQPDGTSVPGEPAS(0.998)PIS(0.002)QR;TQPDGTSVPGEPAS(0.997)PIS(0.003)QR;TQPDGTSVPGEPAS(0.999)PIS(0.001)QR;TQPDGTSVPGEPAS(0.976)PIS(0.024)QR;TQPDGTSVPGEPAS(0.951)PIS(0.049)QR;TQPDGTSVPGEPAS(0.999)PIS(0.001)QR;TQPDGTSVPGEPAS(0.989)PIS(0.011)QR 262.17 9.868899999999999e-67 2057268500.0 168558.2 183079.6 252903.8 356697.0 309008.0 268103.6 207163.1 300561.0 239459.4 245922.0 True False 222156.20137163845 242256.5003832912 249550.1303675926 274466.0175637142 266107.57306633913 251339.03950938414 225600.21457189784 254116.2036546827 252116.7350179462 237312.34563283087 0.9361341938584099 1.0208339550868117 1.05156825997454 1.156560215322162 1.1213389356407955 1.0591064651067725 0.950646768798729 1.0708090343005194 1.0623835618228672 1.0 17.856427629835785 -4.825940606818832 2.297573210563083 1.0630228072547938 0.9125300102346362 0.3236973266111901 0.053804102441407424 0.6820608323900441 4.698622564868693 0.015512953749345438 0.2029491358050347 1.4929985748985789e-05 4.825940606818832 -0.1504927970201576 TQPDGTSVPGEPAS(ph)PISQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 9 TQPDGTSVPGEPASPISQR 19 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 TQPDGTSVPGEPAS(0.999)PIS(0.001)QR;TQPDGTSVPGEPAS(1)PISQR;TQPDGTSVPGEPAS(0.977)PIS(0.023)QR;TQPDGTSVPGEPAS(0.994)PIS(0.006)QR;TQPDGTSVPGEPAS(0.994)PIS(0.006)QR;T(0.002)QPDGT(0.037)S(0.023)VPGEPAS(0.921)PIS(0.016)QR;TQPDGTSVPGEPAS(0.99)PIS(0.01)QR;TQPDGTSVPGEPAS(0.996)PIS(0.004)QR;TQPDGTSVPGEPAS(0.764)PIS(0.236)QR 258.89 3.1572999999999996e-118 1600563200.0 216838.99999999997 229629.6 240923.6 273919.6 302369.2 281135.9 287451.7 256040.2 256527.2 218767.8 True False 253545.5599345314 252425.709118843 246668.13233184145 258572.77287132494 243122.12583546378 266392.6384925335 260222.1940059123 249319.41604701616 260278.42499821685 258428.6703750485 0.9811046102840276 0.9767713030930599 0.9544921311318152 1.0005576103304146 0.9407707182126083 1.030816890811407 1.0069401108950524 0.9647513787273974 1.0071576989522248 1.0 17.979406607601042 -6.761788894558155 24.99999773495802 1.0000431032049113 0.9718283463055484 0.3490817942991583 0.02119362352861895 12.241533325144584 875531.6678579934 0.007178373364562534 0.006719258644870405 1.730657407005792e-07 6.761788894558155 -0.028214756899362925 TQPDGTSVPGEPAS(ph)PISQR ddPTM_PC-9_Lapatinib_30min_R1 1 TQPDGTSVPGEPASPISQR 19 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 TQPDGTSVPGEPAS(0.996)PIS(0.004)QR 195.46 9.2971e-15 295400000.0 26787.0 24851.0 28935.0 26826.0 33178.0 33372.0 33584.0 26893.0 36257.0 29339.0 True False 26405.012467865825 24793.459036340893 26556.07599233002 28798.873528912638 31226.535270457705 31944.75735393159 35322.81519222596 28142.546957723294 32173.35485686392 34410.207058239845 0.76735988316417 0.7205262960021587 0.7717499620790838 0.8369282254003897 0.9074788540971659 0.9283512098565567 1.0265214368644022 0.8178546240681309 0.9349945149243067 1.0 15.070548952850645 -6.016527763024033 1.6337456654548312 0.9349745346887881 0.7423027464187627 0.7136278357858464 0.052640307793495045 0.20863109334945656 1.1217166718671512 0.017968214032226554 0.02990938557052754 9.626584714026298e-07 6.016527763024033 -0.1926717882700254 TQPDGTSVPGEPAS(ph)PISQRLPPK ddPTM_PC-9_Lapatinib_30min_R1 1 TQPDGTSVPGEPASPISQRLPPK 23 1 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 TQPDGTSVPGEPAS(0.96)PIS(0.04)QRLPPK 59.011 0.0030019 4221300.0 46359.0 24224.0 31072.0 26348.0 28052.0 26457.0 19551.0 24537.0 29536.0 23357.0 True False 45697.91215880061 24167.910816318137 28517.380101388542 28285.71981435138 26402.036512353967 25325.49578427929 20563.255116222303 25677.078596722422 26209.344652131516 27394.2263287538 1.668158524003823 0.8822264416699651 1.0409996529617573 1.032543116016452 0.9637810608522862 0.9244829724465294 0.7506419370799493 0.9373171663465082 0.9567470290125114 1.0 14.741584238990693 -4.758618502157284 24.999989463655524 0.9411244699645855 1.668159499481527 0.8831166896558544 0.07912030187687678 26.122803113257227 231469.85074768992 0.02133941100886894 0.14416071001616593 1.7433376031950973e-05 4.758618502157284 0.7270350295169414 TQPDVMS(ph)QNAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQPDVMSQNAR 11 0 Q96Q15;J3KRA9;Q96Q15-4;Q96Q15-3;Q96Q15-2 Q96Q15 SMG1 Serine/threonine-protein kinase SMG1 1 TQPDVMS(1)QNAR 65.495 0.039231 10261000.0 17396.0 18563.0 22649.0 20945.0 20860.0 21784.0 18494.0 17787.0 17658.0 14552.0 True False 20340.799213338487 20405.811961406875 23189.038056810838 19771.51955460619 16772.63274476294 20641.608691459704 16742.114435035008 17320.11009688431 17916.214844346036 17190.162406431373 1.1832813869011711 1.187063360947214 1.3489714354376954 1.1501647911836512 0.9757111275742095 1.2007803186162476 0.9739357918323833 1.0075594219170565 1.0422365083440412 1.0 14.069295554490283 -6.017943626754219 6.837234322309055 1.0408159157515597 1.237343455546413 0.612293020489489 0.07417557205700806 0.1105851251463116 23.96789405017329 0.021542181894321378 0.029420297731063607 9.595251738258356e-07 6.017943626754219 0.19652753979485316 TQPDVMS(ph)QNAR ddPTM_PC-9_Lapatinib_30min_R1 1 TQPDVMSQNAR 11 0 Q96Q15;J3KRA9;Q96Q15-4;Q96Q15-3;Q96Q15-2 Q96Q15 SMG1 Serine/threonine-protein kinase SMG1 1 TQPDVMS(1)QNAR 69.846 0.029675 6377000.0 17529.0 20591.0 17264.0 14416.0 16204.0 14786.0 15627.0 15771.0 17393.0 11189.0 True False 17279.03324557509 20543.32280460727 15844.620560967167 15476.200730366234 15250.912578289728 14153.637247849474 16436.089596501755 16503.778234866102 15434.017183590318 13123.003741594652 1.316698035435858 1.56544364454406 1.2073928250699253 1.1793184727451453 1.1621510500641297 1.0785364026825754 1.2524639876772992 1.25762200177965 1.1761039993207258 1.0 13.679810357669817 -5.378310268491627 6.05379195862888 1.1715161892112569 1.4390807417035727 0.595886217704372 0.09138354967816918 0.14351535284792089 6.528941601646863 0.023076857379066267 0.04882525713315645 4.184944776348188e-06 5.378310268491627 0.2675645524923158 TQPSSGVDSAVGTLPAT(ph)SPQSTSVQAK ddPTM_PC-9_AZD4547_30min_R2 2 TQPSSGVDSAVGTLPATSPQSTSVQAK 27 0 Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 Q13428 TCOF1 Treacle protein 1 TQPSSGVDSAVGTLPAT(0.824)S(0.173)PQS(0.001)T(0.002)SVQAK;TQPSSGVDSAVGTLPAT(0.811)S(0.188)PQST(0.001)SVQAK 173.76 2.856e-17 40400000.0 79540.0 69751.0 92950.0 128336.0 109828.0 103575.0 87143.0 100814.0 80004.0 103346.0 True False 104832.06546522285 92296.6466948527 91717.42226754883 98750.1179714347 94580.27796927547 97098.43887655583 94898.55818164012 85235.51277525435 84232.84810859685 99727.8879960742 1.0511810444571892 0.9254848222443651 0.9196767735736998 0.9901956208610574 0.9483834448895442 0.973633763109253 0.9515749314311741 0.8546808168504446 0.8446268120298775 1.0 16.605709377127724 -7.648371610299623 6.316896573966389 0.8877550039089112 0.9638659350831502 0.24128541766136047 0.052596932052504035 0.2579233908856747 13.239656671244589 0.02420420682685896 0.013766805216844924 2.247130993119906e-08 7.648371610299623 0.07611093117423906 TQPSSGVDSAVGTLPAT(ph)SPQSTSVQAK ddPTM_PC-9_Lapatinib_30min_R1 3 TQPSSGVDSAVGTLPATSPQSTSVQAK 27 0 Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 Q13428 TCOF1 Treacle protein 1 TQPSSGVDSAVGTLPAT(0.942)S(0.058)PQSTSVQAK;TQPSSGVDSAVGTLPAT(0.93)S(0.061)PQS(0.003)T(0.004)S(0.002)VQAK;TQPSSGVDSAVGTLPAT(0.491)S(0.491)PQS(0.006)T(0.01)S(0.003)VQAK 171.89 1.1278e-13 85192000.0 180725.0 149990.0 172770.0 143408.0 166956.0 174234.0 152042.0 134749.0 175875.0 138749.0 True False 178147.82835909387 149642.7073703582 158565.5175114864 153954.70271506373 157135.97632812525 166782.4179792917 159913.9908127804 141009.93046540953 156066.10545414506 162731.57977857906 1.0947342157034974 0.9195677174274947 0.9743991776349665 0.9460653115058699 0.9656145201929001 1.0248927602511104 0.9826856657470392 0.866518537196498 0.95904006872235 1.0 17.312134722797985 -7.608243615653994 24.99999999936069 0.9325869867005494 0.9828902390144068 0.11595167664602157 0.05442333941876034 45.91885817337832 13441.232896438443 0.0245632711633142 0.014181608564633089 2.4646564108009395e-08 7.608243615653994 0.05030325231385735 TQPSSGVDSAVGTLPATS(ph)PQSTSVQAK ddPTM_PC-9_AZD4547_30min_R2 2 TQPSSGVDSAVGTLPATSPQSTSVQAK 27 0 Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 Q13428 TCOF1 Treacle protein 1 TQPSSGVDSAVGTLPAT(0.085)S(0.838)PQS(0.024)T(0.042)S(0.011)VQAK;TQPSSGVDSAVGTLPAT(0.383)S(0.583)PQS(0.012)T(0.017)S(0.005)VQAK 174.61 7.0175e-18 46240000.0 81333.0 62236.0 93448.0 117482.0 105508.0 98942.0 85594.0 101641.0 81385.0 89656.0 True False 107195.2021685061 82352.56990868725 92208.8184621615 90398.3399788063 90860.03540064763 92755.14109895384 93211.70018245047 85934.71892782369 85686.84494922955 86517.1707291625 1.2390049427769096 0.9518638810611095 1.0657863368049378 1.04486010368732 1.0501965636980921 1.072100951952289 1.0773780441138654 0.9932677895447812 0.9904027631401372 1.0 16.400698866835626 -4.747096961020238 24.99094435312632 1.032536225921344 1.2390054745671901 0.7143461478073377 0.04003670754432415 426.610459159511 743305.2352468715 0.010141788377230121 0.2135017726569027 1.7902061262055513e-05 4.747096961020238 0.20646924864584615 TQPSSGVDSAVGTLPATS(ph)PQSTSVQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TQPSSGVDSAVGTLPATSPQSTSVQAK 27 0 Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 Q13428 TCOF1 Treacle protein 1 TQPSSGVDSAVGTLPAT(0.066)S(0.907)PQS(0.008)T(0.014)S(0.005)VQAK;TQPSSGVDSAVGTLPAT(0.225)S(0.705)PQS(0.026)T(0.037)S(0.007)VQAK;TQPSSGVDSAVGTLPAT(0.155)S(0.81)PQS(0.011)T(0.018)S(0.006)VQAK;TQPSSGVDSAVGTLPAT(0.088)S(0.894)PQS(0.005)T(0.009)S(0.003)VQAK 179.22 3.2256e-18 69422000.0 176256.0 187958.0 192407.0 236534.0 241478.0 211652.0 227317.0 217392.0 205996.0 165200.0 True False 206092.6595853173 206617.22806885245 196994.71258761117 223281.76683357471 194162.1193643274 200552.59652794845 205783.8881274384 211685.69034586407 209008.30179385532 195149.45227751997 1.0560760339323685 1.0587640685510318 1.0094556263856025 1.1441577940790122 0.9949406319020128 1.0276872119668812 1.0544938032149602 1.084736277121742 1.0710165944848609 1.0 17.57421988803297 -10.557753874029213 4.946821896580685 0.999999071105082 1.0552417511219605 0.15231921757077405 0.03940855800700835 3.948649666648876e-07 7.706758469290478e-08 0.037321848755205285 0.009051725767752813 2.768510187583292e-11 10.557753874029213 0.05524268001687849 TQPSSGVDSAVGTLPATS(ph)PQSTSVQAK ddPTM_PC-9_Lapatinib_30min_R1 1 TQPSSGVDSAVGTLPATSPQSTSVQAK 27 0 Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 Q13428 TCOF1 Treacle protein 1 TQPSSGVDSAVGT(0.001)LPAT(0.421)S(0.54)PQS(0.013)T(0.018)S(0.006)VQAK 135.6 1.2936e-09 13783000.0 66606.0 54123.0 62614.0 54313.0 59467.0 65102.0 58509.0 58574.0 62496.0 52522.0 True False 65656.18622595548 53997.68151880719 57466.118617029606 58307.359202856685 55969.26797662035 62317.73922017427 61538.3097332643 61295.56187489998 55457.04236794456 61600.3577188341 1.0658409895220677 0.8765806485292144 0.9328861186054368 0.9465425423175653 0.9085867363316941 1.0116457359649527 0.998992733356306 0.9950520442539421 0.9002714338294947 1.0 15.910651108354196 -6.764261917464371 24.9980618978628 0.9819956597209315 0.9415178025595854 0.09241747843865089 0.05403591907519785 169.01319943476238 1496864.7337768 0.018109847194255402 0.016671323826414175 1.7208304510749938e-07 6.764261917464371 -0.04047785716134611 TQPT(ph)SLPK ddPTM_PC-9_AZD4547_30min_R2 1 TQPTSLPK 8 0 E7EVA0;P27816-4;H7C4C5;B5MEG9;P27816;P27816-6;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 T(0.016)QPT(0.868)S(0.116)LPK 75.652 0.036045 0.0 41292.0 61884.0 48478.0 53323.0 54143.0 77027.0 57780.0 66504.0 70999.0 59000.0 True False 54421.99707304473 81886.79279242246 47835.15004503747 41030.20618213762 46626.17902620905 72210.4895133424 62922.30806530832 56227.334909888625 74751.86219266866 56934.42795820232 0.9558715003336459 1.4382649607463975 0.8401796902246043 0.7206572131059158 0.8189452445265466 1.268309739870484 1.105171516108003 0.9875805716563483 1.3129465750941904 1.0 15.797013686285693 -6.7629102183029275 24.999447835136518 1.132173562852916 0.9622698831453199 0.16420850336337423 0.2026709256673216 88.14306140845969 1498121.1340721427 0.07475018664370768 0.06948632057703603 1.7261947113343202e-07 6.7629102183029275 -0.169903679707596 TQPTS(ph)LPKQPAPTTIGGLNK ddPTM_PC-9_AZD4547_30min_R2 1 TQPTSLPKQPAPTTIGGLNK 20 1 E7EVA0;P27816-4;H7C4C5;B5MEG9;P27816;P27816-6;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 T(0.001)QPT(0.165)S(0.833)LPKQPAPTTIGGLNK 88.637 0.0010452 0.0 9706.2 7807.3 13602.0 18491.0 18376.0 19209.0 9772.5 12221.0 13326.0 14662.0 True False 12792.569698498179 10330.857044927281 13421.628592611085 14228.185633102154 15824.809592848891 18007.858193384083 10642.233568158967 10332.5252606422 14030.385154431808 14148.687842765466 0.9041523737509906 0.7301636137381937 0.9486129556158 1.0056187394350733 1.118464819403056 1.2727581803701955 0.7521710625342952 0.7302815197753795 0.9916386106154608 1.0 13.788380642464322 -5.415772989837561 6.241027262224077 0.9784947946438944 0.818545133100916 0.15102054281428956 0.1534933314846426 0.4832591491391829 24.019331332372627 0.0448212388684438 0.0943718408575624 3.8390786561797394e-06 5.415772989837561 -0.1599496615429784 TQQFS(ph)PTGK ddPTM_PC-9_AZD4547_30min_R2 1 TQQFSPTGK 9 0 Q4G0A6 Q4G0A6 FAM188B Protein FAM188B 1 T(0.002)QQFS(0.765)PT(0.232)GK 72.096 0.033208 11971000.0 62417.0 56103.0 74048.0 92692.0 83145.0 87619.0 65157.0 83356.0 72153.0 72552.0 True False 82264.30764574808 74237.19759603897 73066.07513789636 71323.29147712424 71601.75193716913 82140.17007892768 70955.84677416574 70475.24553032433 75966.86027673101 70011.9765631102 1.1750033591980278 1.0603499749663554 1.043622516099558 1.0187298656370882 1.0227071917134902 1.1732302687510168 1.0134815535482662 1.006616995976346 1.0850552149210206 1.0 16.09531411661063 -4.75977002969194 4.084419753144196 1.0475141922195161 1.188765469405685 0.3851952670591028 0.04874681694412878 0.2662372340714685 8.501060711226382 0.01229903468049083 0.11459603064854189 1.738721283505037e-05 4.75977002969194 0.14125127718616892 TQQFS(ph)PTGK ddPTM_PC-9_Lapatinib_30min_R1 1 TQQFSPTGK 9 0 Q4G0A6 Q4G0A6 FAM188B Protein FAM188B 1 TQQFS(0.846)PT(0.154)GK 122.18 0.001572 9754300.0 54681.0 53209.0 59150.0 52950.0 56115.0 54297.0 51261.0 53932.0 58839.0 44814.0 True False 53901.23891273268 53085.7978296512 54286.91532560287 56844.11963602199 52814.42602633475 51974.84388248902 53915.043758000706 56437.87760844581 52211.93221786182 52560.04018909848 1.0255174600097126 1.0100029916008657 1.0328552856940654 1.0815082985384032 1.0048399094886735 0.9888661366219648 1.0257801090719727 1.0737791943346275 0.993376946250721 1.0 15.681678758341178 TQQFSPT(ph)GK ddPTM_PC-9_Lapatinib_30min_R1 1 TQQFSPTGK 9 0 Q4G0A6 Q4G0A6 FAM188B Protein FAM188B 1 TQQFS(0.07)PT(0.93)GK 102.53 0.0076953 11195000.0 74802.0 61541.0 69620.0 61150.0 68632.0 66794.0 54543.0 54233.0 63422.0 44763.0 True False 73735.30976299316 61398.5055955678 63896.11234097158 65647.17499042011 64595.20069570354 63937.37632441891 57366.96965905132 56752.86316730031 56278.74649673229 52500.22490705171 1.4044760740270505 1.1694903346465646 1.2170635926626137 1.2504170240535968 1.2303795042795571 1.217849569932623 1.0926995029186233 1.0810022865192983 1.0719715314814406 1.0 15.680035982739508 -7.466002076894359 0.6105929378684685 1.0020127688188694 1.2715627073228237 0.7305071280021957 0.05731054633326498 0.42310133508322423 0.3185498400430763 0.05287509367493823 0.034117886266237914 3.419778070946411e-08 7.466002076894359 0.26954993850395437 TQQHYYER ddPTM_PC-9_AZD4547_30min_R2 1 TQQHYYER 8 0 P11216 P11216 PYGB Glycogen phosphorylase, brain form 0 106.88 0.0032052 1964100.0 13072.0 16802.0 15564.0 15321.0 15009.0 18789.0 13074.0 17202.0 17000.0 13032.0 False True 17228.624085509062 22232.917918982006 15357.611190663056 11788.980157090373 12925.259424198353 17614.12085977894 14237.560672306006 14543.826162635407 17898.585293812142 12575.753646632085 1.369987403508263 1.7679193266429967 1.2212080183978462 0.9374372692365505 1.027792034369238 1.4006413734493106 1.1321437324846906 1.1564973814933464 1.423261443945792 1.0 13.618357240787283 -5.387011070683355 6.353642063787534 1.1587421529625983 1.5653349279777937 0.4709391284482116 0.173348981402074 0.1899313036040063 8.925193252451617 0.04535644859438081 0.09560518927688098 4.101936465289631e-06 5.387011070683355 0.4065927750151954 TQQHYYER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TQQHYYER 8 0 P11216 P11216 PYGB Glycogen phosphorylase, brain form 0 ; 86.624 0.010353 3808100.0 20526.8 31874.0 27670.0 22224.2 23676.0 18215.6 23435.1 18465.2 16617.3 17861.9 False True 24001.58181721983 35038.24007207254 28329.757739059358 20979.05012582856 19036.857759588085 17260.341869268872 21215.157672568883 17980.50806549662 16860.296575656997 21100.12107527741 1.1375091987193384 1.6605705695748896 1.3426348426148498 0.9942620732356504 0.9022155698382789 0.8180209870687647 1.0054519401514836 0.852151890567302 0.7990616032725931 1.0 14.364963656880068 -5.785240938803783 3.260166078439003 0.8943447587153104 1.4226305144260492 0.7249246453312552 0.1338632583364663 0.11074660441296075 2.430704945120667 0.03675711399855517 0.06221425922057405 1.639679855789629e-06 5.785240938803783 0.5282857557107388 TQQHYYER ddPTM_PC-9_Lapatinib_30min_R1 2 TQQHYYER 8 0 P11216 P11216 PYGB Glycogen phosphorylase, brain form 0 ; 89.88600000000001 0.0083 5175600.0 21591.0 32933.0 31637.0 29690.0 40527.0 38626.0 42637.0 46739.0 31442.0 32871.0 False True 21283.108380695525 32856.7456618975 29035.92798235161 31873.50164293658 38143.28153914764 36974.0560216038 44844.53523555676 48910.66456910829 27900.67086106173 38552.7085521457 0.5520522209719293 0.8522551824719671 0.753148846677741 0.826751292968821 0.9893800713782723 0.9590520980281673 1.1632006393247534 1.2686699950783642 0.7237019630754034 1.0 15.234544600973262 -6.022769110995754 0.9871205332165585 1.056095595547967 0.6806680895978184 0.4628732824037286 0.1479000384377034 0.5184296422517107 1.030023154556935 0.06290979718688332 0.13185994603564175 9.489228160461414e-07 6.022769110995754 -0.3754275059501485 TQQS(ph)PISNGSPELGIK ddPTM_PC-9_AZD4547_30min_R2 1 TQQSPISNGSPELGIK 16 0 Q15723-2;Q15723-3;Q15723-1;Q15723 Q15723-2 ELF2 ETS-related transcription factor Elf-2 1 T(0.003)QQS(0.988)PIS(0.009)NGSPELGIK 110.15 0.00060323 7487400.0 20586.0 15310.0 22979.0 28515.0 29228.0 25987.0 18227.0 27912.0 23285.0 23203.0 True False 27131.91978459989 20258.658096632204 22674.283445788133 21941.30730235833 25170.196712004075 24362.02878189767 19849.167689622256 23598.84175395182 24515.797562730346 22390.670032443544 1.21175113318567 0.9047812355448897 1.0126665889378763 0.9799308046863225 1.124137717876824 1.08804375869939 0.8864927963683663 1.0539587122563847 1.0949112968574652 1.0 14.45061008049655 -4.738139067287092 24.99883026015684 1.0181249805134385 1.2117519466356685 0.38360124096791215 0.07436295022665636 2309.565371379511 2477797.8681754265 0.018848829910907677 1.0975136417811326 1.8275149260949497e-05 4.738139067287092 0.19362696612223007 TQQSPIS(ph)NGSPELGIK ddPTM_PC-9_AZD4547_30min_R2 1 TQQSPISNGSPELGIK 16 0 Q15723-2;Q15723-3;Q15723-1;Q15723 Q15723-2 ELF2 ETS-related transcription factor Elf-2 1 T(0.007)QQS(0.205)PIS(0.675)NGS(0.113)PELGIK 94.538 0.0025862 6759500.0 11382.0 15404.0 12656.0 23433.0 23612.0 18659.0 15895.0 16564.0 17257.0 17662.0 True False 15001.239239692799 20383.041758362007 12488.1731707165 18030.88388624103 20333.881372787764 17492.24978032972 17309.62420730487 14004.414402853909 18169.16978913625 17043.65875589441 0.8801654301195595 1.1959311114060354 0.7327166865739769 1.0579233100407621 1.193046731574314 1.0263201130027417 1.0156049505109037 0.8216788779586776 1.0660369378055397 1.0 14.056947451168403 -7.569811535760553 24.99996906395664 0.950043111695731 1.0199945099878178 0.02480730758747396 0.14031668489754978 438.04355611457964 233330.6830392093 0.0649249713006373 0.037484469538266334 2.692703062241042e-08 7.569811535760553 0.06995139829208685 TQS(ph)APLPQNAQALQHLVIQQQHQQFLEK ddPTM_PC-9_AZD4547_30min_R2 1 TQSAPLPQNAQALQHLVIQQQHQQFLEK 28 0 P56524-2;P56524 P56524-2 HDAC4 Histone deacetylase 4 1 T(0.172)QS(0.828)APLPQNAQALQHLVIQQQHQQFLEK 94.295 9.707200000000001e-10 10762000.0 12768.0 9788.4 18235.0 34553.0 31800.0 23511.0 19211.0 22545.0 19665.0 23805.0 True False 16827.95840910187 12952.308877405274 17993.19198546266 26587.33968852843 27385.118907955726 22040.85345331112 20920.74178336168 19061.188282561052 20704.451753106816 22971.594195678073 0.732555096775474 0.5638402266326884 0.7832800733023545 1.1574007211711337 1.192129665650633 0.959482971254034 0.9107222426599262 0.8297721142117018 0.9013066997762914 1.0 14.487563360705465 -5.552399062704557 6.6528336419764615 0.9889274127777711 0.6534175010166343 0.617535273559291 0.11144808483075022 0.11918815925265049 17.344463895178755 0.03446417951703536 0.06134789042963036 2.802856976773133e-06 5.552399062704557 -0.33550991176113676 TQS(ph)APLPQNAQALQHLVIQQQHQQFLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQSAPLPQNAQALQHLVIQQQHQQFLEK 28 0 P56524-2;P56524 P56524-2 HDAC4 Histone deacetylase 4 1 T(0.441)QS(0.559)APLPQNAQALQHLVIQQQHQQFLEK 49.118 0.011189 6887000.0 9017.8 10531.0 9610.2 12724.0 13162.0 11919.0 14231.0 12535.0 8961.6 10271.0 True False 10544.335430331324 11576.448083045607 9839.343614886462 12011.115531764586 10583.000584207572 11293.94665779967 12882.936656482278 12205.969531930332 9092.646446318467 12133.050994808737 0.8690588570708916 0.954125066151846 0.8109537839325275 0.9899501400681229 0.8722456197320549 0.930841439851519 1.0618052015106825 1.0060099093915285 0.7494113764302861 1.0 13.56665475784057 -7.000840226387688 24.988370280836435 0.9607382838358294 0.9023558154609027 0.07655079880324267 0.0889871056903106 83.22680497681982 2475243.398040679 0.031205385377012045 0.027190756601910147 9.980671775566429e-08 7.000840226387688 -0.058382468374926666 TQS(ph)ASPPPKER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQSASPPPKER 11 1 Q9UN81 Q9UN81 L1RE1 LINE-1 retrotransposable element ORF1 protein 1 T(0.001)QS(0.911)AS(0.088)PPPKER 114.87 0.0068323 4521500.0 22117.0 17982.0 21588.0 25196.0 25203.0 25277.0 18165.0 24886.0 24463.0 22734.0 True False 25860.971269338188 19767.134121102106 22102.73979294592 23784.34980653415 20264.653071249315 23951.42962238463 16444.27969678873 24232.76886889656 24820.725095550857 26855.494237755032 0.9629676162496877 0.7360554956129725 0.8230248751807586 0.8856418577132984 0.7545812745743504 0.8918632965880144 0.6123245973879861 0.9023393371338037 0.9242326682134349 1.0 14.712929652068663 -7.986427387506292 24.996719714164065 0.9458396557891509 0.8073288465845126 0.3083172725110972 0.09329407901899142 261.5221094478438 481645.85809409077 0.048539961009145205 0.023300043775852958 1.0317455692111834e-08 7.986427387506292 -0.1385108092046382 TQS(ph)ESGDVSR ddPTM_PC-9_AZD4547_30min_R2 2 TQSESGDVSR 10 0 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 T(0.049)QS(0.902)ES(0.049)GDVSR;T(0.007)QS(0.988)ES(0.003)GDVS(0.002)R 117.03 0.00099104 5537900.0 22959.0 18031.7 31352.0 49506.0 36776.0 31882.0 23762.0 40078.0 32925.0 36485.0 True False 30259.484423133625 23860.09439588784 30936.2519949671 38093.156560075455 31670.287199967926 29888.413499998518 25876.77196690646 33884.866000819784 34665.3482822803 35207.6712551697 0.8594571394349318 0.6776958982308254 0.8786793017565623 1.0819561533619486 0.8995280309917583 0.8489176487527521 0.7349753915663155 0.9624284933597907 0.984596454307958 1.0 15.103602185571136 -1.5228787452803376 0.11489285721814849 1.0273499011175515 0.34251286119096985 0.17818260966326083 0.10533334783686173 209.3750342939949 1.6732104547135278 0.9341819790397511 22.822098281616285 0.029999999999999995 1.5228787452803376 -0.6848370399265817 TQS(ph)GNFYTDTLGMAEFR ddPTM_PC-9_Lapatinib_30min_R1 1 TQSGNFYTDTLGMAEFR 17 0 H0YDJ2;E9PP16;Q8ND30-3;Q8ND30-2;Q8ND30 H0YDJ2 PPFIBP2 Liprin-beta-2 1 T(0.045)QS(0.848)GNFYT(0.022)DT(0.085)LGMAEFR 89.374 0.0022600999999999997 2699600.0 9534.3 7756.7 12630.0 8904.9 9762.5 10163.0 9007.1 9487.1 11594.0 9399.5 True False 9398.339133623518 7738.7398377202235 11591.610153209884 9559.796051875574 9188.288943813479 9728.352181110116 9473.443565921227 9927.905300361315 10288.161629767501 11024.191050953526 0.8525196171024828 0.7019780228727865 1.0514703618282522 0.8671653101520505 0.833466047653333 0.8824549698155559 0.8593323103831578 0.9005563541555832 0.9332350629824795 1.0 13.42838517505143 -14.522878740999877 0.07780397869244988 1.4271017710203022 0.7417571836901448 0.23145965635116839 0.07918837167271645 418.9682267829502 2.3082939335777986 30.77853223516086 3.0430436668447367 3.0000000295683746e-15 14.522878740999877 -0.6853445873301575 TQS(ph)LPVTEK ddPTM_PC-9_AZD4547_30min_R2 1 TQSLPVTEK 9 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 TQS(0.568)LPVT(0.432)EK 142.89 0.00063525 110780000.0 160660.0 141070.0 165590.0 212510.0 181270.0 142830.0 131200.0 175700.0 114280.0 129830.0 True False 211746.53806440363 186668.11872579384 163394.16840541596 163519.1027467708 156103.78944795995 133898.81752100843 142876.54583192218 148549.602184341 120320.6074927559 125284.69121717663 1.6901229991248365 1.489951540864727 1.3041830316058158 1.3051802351758697 1.245992530542774 1.068756415649375 1.1404150374944908 1.185696358758114 0.9603775714638936 1.0 16.934850614121594 -1.522878745280651 0.29410819136704003 1.0149472510468436 6.6273334404476865 0.9188996058689787 0.06050920949084379 13.879791394821495 0.19735888038309476 0.06356153291407089 40.7063093410547 0.029999999999978353 1.522878745280651 5.612386189400842 TQS(ph)LPVTEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TQSLPVTEK 9 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 T(0.014)QS(0.734)LPVT(0.252)EK;T(0.013)QS(0.765)LPVT(0.222)EK;TQS(0.892)LPVT(0.108)EK 137.01 0.00096947 161684000.0 633590.0 583729.0 388487.0 405599.0 411310.0 305270.0 371530.0 351043.0 276099.0 229627.0 True False 740844.2730270817 641677.7573894353 397750.0034251516 382874.6029997005 330716.75811354053 289261.1038028782 336335.98875573394 341828.4932108035 280136.42554700986 271256.55737366795 2.731157101601551 2.365575098357883 1.4663240117629057 1.4114851515728475 1.2192028141755242 1.0663746034511827 1.2399183710512707 1.2601667459043933 1.0327360498095148 1.0 18.04929848821927 -5.138713255706693 1.260126535738442 1.1563667215196287 3.024137416923105 0.9641721292806169 0.10589719373423749 0.13120471283618135 0.2762854688048026 0.032202048849705844 0.26992274624836965 7.2658552947213765e-06 5.138713255706693 1.8677706954034763 up TQS(ph)LPVTEK ddPTM_PC-9_Lapatinib_30min_R1 2 TQSLPVTEK 9 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 T(0.004)QS(0.992)LPVT(0.003)EK;T(0.123)QS(0.84)LPVT(0.037)EK 103.44 0.0028554 195340000.0 348470.0 339970.0 297830.0 242390.0 256990.0 260280.0 270530.0 289880.0 249550.0 263350.0 True False 343500.7538984285 339182.82035269536 273343.5670570463 260216.1691893368 241874.3534617796 249148.43114231413 284536.7196865435 303348.88305896753 221443.0511220011 308869.69660818274 1.112121900175196 1.098142110014005 0.8849802038164877 0.8424787929889883 0.783095124312599 0.8066457599379582 0.9212192805288151 0.9821257520247489 0.7169465103043537 1.0 18.236638808666676 -5.273892764756126 4.160651205415743 0.8606754326413221 1.1111374061620947 0.5728202493610088 0.08233478015789662 0.13590232767872612 5.767865175444405 0.021533427576754773 0.05414200320168193 5.322396627420391e-06 5.273892764756126 0.2504619735207726 TQS(ph)LSALPK ddPTM_PC-9_AZD4547_30min_R2 3 TQSLSALPK 9 0 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 T(0.01)QS(0.987)LS(0.003)ALPK;T(0.03)QS(0.966)LS(0.004)ALPK;T(0.435)QS(0.562)LS(0.004)ALPK 90.73100000000001 0.0083471 74999000.0 343815.0 340433.0 447616.0 593181.0 514671.0 477272.0 451495.0 488043.0 415508.0 475278.0 True False 453141.01820374106 450471.3097198429 441680.31937290163 456432.2850050929 443217.81551812816 447428.10639142204 491677.1803382892 412627.168462451 437470.9046036062 458638.66188336385 0.9880131263748085 0.9821921856086394 0.9630246119225446 0.9951892915673297 0.9663769157577968 0.975556889500099 1.072036051909046 0.8996781186479783 0.9538465484073368 1.0 18.80699844940873 TQS(ph)LSALPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TQSLSALPK 9 0 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 T(0.095)QS(0.807)LS(0.097)ALPK;T(0.001)QS(0.989)LS(0.01)ALPK;T(0.442)QS(0.51)LS(0.048)ALPK;T(0.025)QS(0.97)LS(0.005)ALPK 106.49 0.0025656999999999998 115264000.0 295459.0 332514.0 293075.0 422759.0 558417.0 471238.0 530309.0 513794.0 489556.0 435669.0 True False 345474.37311874976 365523.79241153057 300063.0194931273 399073.1838331705 448999.1974799745 446525.4497129126 480074.2924153215 500307.4519097417 496714.83035103907 514652.34094609396 0.671277181958715 0.7102343918995532 0.5830402305010728 0.7754228477802075 0.8724320512262157 0.867625412704929 0.9328128023915969 0.9721270304338229 0.9651463538238647 1.0 18.973238663306795 -6.385346456337582 1.0324881204561986 0.9669518480532107 0.6516343142420046 0.896941559273328 0.0435940936126685 0.1597066904754581 0.36169376289051985 0.021308298416106104 0.02864054491237456 4.1176890137427604e-07 6.385346456337582 -0.3153175338112061 TQS(ph)PEFEAQSSK ddPTM_PC-9_AZD4547_30min_R2 2 TQSPEFEAQSSK 12 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 T(0.001)QS(0.999)PEFEAQSSK;T(0.023)QS(0.97)PEFEAQS(0.006)S(0.001)K 162.79 0.00012823 74434000.0 180751.0 195868.0 220883.0 196887.0 215454.0 256400.0 193574.0 266740.0 189852.0 201967.0 True False 238226.05814564315 259178.50059249852 217953.94709761173 151497.74402382685 185541.93110675112 240367.26746752474 210801.71099747333 225521.46207541935 199887.18912946037 194896.19680397082 1.2223227648985582 1.329828415549759 1.1183078514191465 0.7773252967896818 0.9520038571782479 1.2333091738536557 1.081610182519367 1.157136289848959 1.025608464440738 1.0 17.572346412618117 -5.448580006814993 5.791363861378036 1.0391361523654719 1.2688254681539235 0.4017201136902916 0.1173042617009669 0.2433134977449302 14.350606037799821 0.03382786439554524 0.07102595851141316 3.5597540531610996e-06 5.448580006814993 0.22968931578845164 TQS(ph)PEFEAQSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TQSPEFEAQSSK 12 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 TQS(1)PEFEAQSSK;T(0.049)QS(0.951)PEFEAQSSK;T(0.02)QS(0.835)PEFEAQS(0.143)S(0.001)K 146.84 5.6141000000000003e-05 63636000.0 85177.0 108320.0 97520.0 94438.0 117734.0 75552.0 107090.0 72003.0 70186.0 66883.0 True False 99595.78377756552 119073.29373805934 99845.24664665939 89146.94503212687 94664.86786059079 71589.92011830525 96945.65993554133 70112.99754348464 71212.33747113336 79008.35845446325 1.2605727511092122 1.5070974269980266 1.2637301748802383 1.1283229619750552 1.1981626971170554 0.9061056515883236 1.22703042857695 0.8874124069277369 0.9013266300448053 1.0 16.269717666547088 -6.063213978519888 0.6864800111402665 0.9609992758456312 1.426288847498302 0.6232443657179911 0.11796022429643303 0.5817150487212135 0.5467305382387718 0.0686668884801696 0.1649595768106005 8.645418508096441e-07 6.063213978519888 0.4652895716526708 TQS(ph)PEFEAQSSK ddPTM_PC-9_Lapatinib_30min_R1 1 TQSPEFEAQSSK 12 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 T(0.416)QS(0.524)PEFEAQS(0.055)S(0.005)K 134.25 5.6822e-05 45840000.0 99080.0 143410.0 156250.0 124670.0 164930.0 182120.0 155590.0 144940.0 149340.0 130990.0 True False 97667.10103095342 143077.9429560844 143403.7281424419 133838.64768692869 155229.14166485608 174331.15214245554 163645.68889228304 151674.44152948377 132519.7565800827 153631.44696679598 0.635723368875527 0.9313063554430201 0.9334269186010818 0.8711670060352613 1.0103995290652013 1.134736120659811 1.0651835423228906 0.9872616871353482 0.8625822329768456 1.0 17.229114027341467 -4.234841670362264 1.0299325569791296 0.9999546902904024 6.205161793466041e-27 0.6336860220088856 0.07838165617323878 3.5315995025010434 1.3894968323198618 0.027203049732077284 5.098564290953449 5.823154723527517e-05 4.234841670362264 -0.9999546902904024 TQS(ph)PGGCSAEAVLAR ddPTM_PC-9_AZD4547_30min_R2 2 TQSPGGCSAEAVLAR 15 0 K7ESM2;K7ELS4;K7EJA3;K7ERG7;Q96MH2 K7ESM2 HEXIM2 Protein HEXIM2 1 T(0.389)QS(0.611)PGGCSAEAVLAR;T(0.077)QS(0.922)PGGCSAEAVLAR 194.67 1.3254000000000002e-09 169626000.0 230800.0 236860.0 287920.0 422560.0 372630.0 331120.0 262560.0 296120.0 276440.0 314170.0 True False 304189.59906177234 313420.3629502482 284101.99267641385 325145.32048692065 320896.7565619984 310415.0140555645 285927.3313538821 250361.45816065575 291052.05403655465 303171.003925905 1.0033598039478615 1.0338071876651111 0.9371014674802093 1.0724815905098437 1.0584678363252231 1.0238941390695462 0.9431222895701554 0.8258093779372255 0.9600260257992476 1.0 18.209772251386703 -7.344226359047807 4.300971855006674 0.9143210610721473 1.022313364474688 0.3882279498127097 0.05391472118277544 0.20781045153267608 7.052216559598821 0.02320891130202676 0.015343025236808696 4.526615862236653e-08 7.344226359047807 0.10799230340254073 TQS(ph)PGGCSAEAVLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TQSPGGCSAEAVLAR 15 0 K7ESM2;K7ELS4;K7EJA3;K7ERG7;Q96MH2 K7ESM2 HEXIM2 Protein HEXIM2 1 T(0.071)QS(0.928)PGGCS(0.001)AEAVLAR;T(0.017)QS(0.983)PGGCSAEAVLAR;T(0.419)QS(0.576)PGGCS(0.005)AEAVLAR 198.67 6.894600000000001e-10 126430200.0 233786.0 204317.9 266174.0 287421.0 330740.0 212213.0 275949.5 239307.0 235301.0 214094.4 True False 273361.35231602343 224601.23082203968 272520.5976305162 271317.73320145503 265933.87123695604 201084.17670036448 249809.56565862912 233025.4448167256 238741.83197924227 252908.0199496627 1.0808726127800599 0.8880747667343367 1.0775482631383422 1.0727921291521578 1.0515043029868563 0.7950881776718155 0.987748691039334 0.9213841651328636 0.9439867981519923 1.0 17.94825326137134 TQS(ph)PGGCSAEAVLAR ddPTM_PC-9_Lapatinib_30min_R1 4 TQSPGGCSAEAVLAR 15 0 K7ESM2;K7ELS4;K7EJA3;K7ERG7;Q96MH2 K7ESM2 HEXIM2 Protein HEXIM2 1 T(0.396)QS(0.604)PGGCSAEAVLAR;T(0.006)QS(0.99)PGGCS(0.003)AEAVLAR;T(0.034)QS(0.952)PGGCS(0.014)AEAVLAR;T(0.001)QS(0.986)PGGCS(0.013)AEAVLAR 204.78 8.397200000000001e-13 163394300.0 241894.0 226207.3 239303.0 209360.0 236144.9 233249.0 210085.5 199122.1 189436.0 157817.4 True False 238444.5472020731 225683.5308949851 219628.43107629323 224757.03280448643 222255.32126073635 223273.48399997596 220962.69923375396 208374.03969696455 168099.72283048424 185095.927311533 1.288221467999939 1.219278750067469 1.1865654434775268 1.2142732477641187 1.200757490934205 1.2062582210368502 1.1937739659817255 1.1257624234284334 0.9081762374358316 1.0 17.497913626198 -8.061690616951225 2.974726969260849 0.9551241991776448 1.213247253141718 0.8963028598300538 0.035041233505855564 0.07690477055376652 1.2738599223324112 0.027337084073877672 0.009305483962532807 8.675797027874151e-09 8.061690616951225 0.2581230539640732 TQS(ph)SLTVSEVLTR ddPTM_PC-9_AZD4547_30min_R2 2 TQSSLTVSEVLTR 13 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 TQS(0.995)S(0.004)LT(0.001)VSEVLTR;TQS(0.995)S(0.005)LTVSEVLTR 181.69 5.513e-05 31170000.0 40354.0 41918.0 47350.0 56656.0 54736.0 50468.0 41307.0 61939.0 43407.0 47210.0 True False 53185.73258465671 55467.173748832734 46722.10806205962 43594.83452647429 47136.851212134105 47312.227981868295 44983.24297773779 52367.75076662447 45701.405402853154 45557.19226960562 1.1674497469006804 1.2175283634816703 1.0255704035832602 0.9569254019975995 1.034674194431916 1.0385237900939206 0.987401565740241 1.149494693542882 1.0031655404133355 1.0 15.47539121475312 -5.266499418195044 24.713299425132895 1.026938794872142 1.1924890623729505 0.6506535972369071 0.04921965009931214 195.35406050917203 954116.6016096403 0.012947314525387412 0.028367825860783725 5.413779731421357e-06 5.266499418195044 0.16555026750080848 TQS(ph)SLTVSEVLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TQSSLTVSEVLTR 13 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 T(0.064)QS(0.906)S(0.03)LTVSEVLTR;T(0.016)QS(0.901)S(0.075)LT(0.006)VS(0.001)EVLTR 114.54 0.00030321 15100200.0 28849.0 36463.0 20631.7 25849.0 28980.0 20103.2 31519.0 21334.8 19152.9 21949.5 True False 33732.56590627738 40082.805664428066 21123.63797415798 24400.76433358872 23301.577034670667 19048.952802339 28533.292142201142 20774.78410608915 19432.97492877309 25928.770597853614 1.300970509919578 1.545881456783999 0.8146795041607795 0.9410690816019104 0.8986765086578988 0.7346647127155298 1.100449095128449 0.8012251883553974 0.7494753696645282 1.0 14.662266182561803 -5.26519484829533 24.99988610858869 0.8784572377793078 1.4234260046076748 0.7642658661816231 0.12071364188660637 126.46790664659046 841893.1844052699 0.030187124685918908 0.06694866961178665 5.430066543019074e-06 5.26519484829533 0.5449687668283669 TQS(ph)SLTVSEVLTR ddPTM_PC-9_Lapatinib_30min_R1 1 TQSSLTVSEVLTR 13 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 T(0.059)QS(0.938)S(0.003)LTVSEVLTR 200.0 4.5202e-07 11309000.0 18470.0 27578.0 25332.0 27383.0 24868.0 27560.0 32926.0 25328.0 21142.0 21730.0 True False 18206.614413016832 27514.144835387284 23249.30074434781 29396.83716701019 23405.313132369105 26381.323045497855 34630.74717184469 26504.831344409897 18760.76532487015 25486.001546595056 0.7143770426180974 1.0795787163821775 0.9122380653490123 1.1534503407003687 0.9183595586611768 1.035129931906577 1.358814449906183 1.0399760549316515 0.7361203871297967 1.0 14.63741742880664 -4.756563201533126 24.94795526035956 1.0349678492535201 0.7143765395405659 0.2651633695544008 0.15495890840805676 204.45252417757567 1045914.3190741566 0.039030558585020164 0.311465687999553 1.751607509634862e-05 4.756563201533126 -0.32059130971295424 TQS(ph)TFDPFEKPANQVK ddPTM_PC-9_AZD4547_30min_R2 2 TQSTFDPFEKPANQVK 16 1 O94921;O94921-3;O94921-2;C9JWL6;F8WF96;C9IYJ9 O94921 CDK14 Cyclin-dependent kinase 14 1 T(0.387)QS(0.46)T(0.154)FDPFEKPANQVK;T(0.168)QS(0.702)T(0.13)FDPFEKPANQVK 98.882 0.00093879 25051000.0 131242.0 124479.0 145562.0 183962.0 184482.0 158797.0 176096.0 208869.0 174385.0 168678.0 True False 172974.22599681586 164714.4024304821 143631.75277147882 141552.4030845676 158869.85869111578 148867.39848689726 191768.20285684548 176593.09538213522 183602.6350859666 162772.63456158715 1.0626738730543113 1.0119293262907791 0.8824072495867471 0.8696326840554356 0.9760231449163237 0.9145726423108999 1.178135399561205 1.0849065376239204 1.127969916936487 1.0 17.312498647623258 -7.252674485135266 24.940238381272057 1.1048285096337478 0.9496231402585643 0.5170923797858816 0.06841038775171475 494.44490739301744 1406929.8234314905 0.027311946583320715 0.02083492718161409 5.588889393968886e-08 7.252674485135266 -0.15520536937518348 TQS(ph)TFDPFEKPANQVK ddPTM_PC-9_Lapatinib_30min_R1 1 TQSTFDPFEKPANQVK 16 1 O94921;O94921-3;O94921-2;C9JWL6;F8WF96;C9IYJ9 O94921 CDK14 Cyclin-dependent kinase 14 1 T(0.156)QS(0.661)T(0.183)FDPFEKPANQVK 53.059 0.03663 13589000.0 59559.0 63471.0 56339.0 51385.0 65683.0 55792.0 53097.0 47082.0 59171.0 46109.0 True False 58709.677738217084 63324.036799146605 51707.02489482912 55164.02431533501 61819.65507774647 53405.90621750422 55846.1028543837 49269.60160129136 52506.538881746834 54078.87921361948 1.0856304455997556 1.1709569007339704 0.9561408381001908 1.0200659687755185 1.1431386148657001 0.9875557148021333 1.0326786291887342 0.9110692070127643 0.9709250569772041 1.0 15.722777631581739 -7.228034611981556 1.7625140274373945 0.9610931042579776 1.0691864455083806 0.32763848385193683 0.06436329192621486 0.4385104220896648 2.663515871835013 0.03480249917699783 0.022118712654717987 5.9151449034716604e-08 7.228034611981556 0.10809334125040304 TQSAPLPQS(ph)TLAQLVIQQQHQQFLEK ddPTM_PC-9_AZD4547_30min_R2 1 TQSAPLPQSTLAQLVIQQQHQQFLEK 26 0 Q9UKV0-10;Q9UKV0-3;Q9UKV0-4;Q9UKV0-2;Q9UKV0;Q9UKV0-5;Q9UKV0-7;B7Z3P7;B5MCF1;Q9UKV0-11;Q9UKV0-9;Q9UKV0-8;Q9UKV0-6 Q9UKV0-10 HDAC9 Histone deacetylase 9 1 T(0.156)QS(0.13)APLPQS(0.357)T(0.357)LAQLVIQQQHQQFLEK 130.81 3.7889e-12 8594500.0 32197.0 25189.0 39659.0 58246.0 46992.0 44879.0 39841.0 47981.0 56925.0 41230.0 True False 42434.976260796764 33330.851652257916 39133.095747269756 44818.284591729374 40467.971940964 42072.70903539408 43386.771817756104 40566.63894369312 59933.93928530923 39786.550249435306 1.066565861949769 0.8377416851497695 0.9835759949513385 1.1264682238281134 1.0171269357925388 1.057460593382087 1.0904884074077745 1.019606844256845 1.5063869299942605 1.0 15.279993193037193 -8.126528710570389 21.651735292838946 1.2565488843229782 1.0236383608737747 0.3135730724133834 0.1350891614719063 6.040430916667802 1016.5883068219786 0.08606961158826894 0.03253113268386289 7.472592323479357e-09 8.126528710570389 -0.2329105234492035 TQSAPLPQS(ph)TLAQLVIQQQHQQFLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQSAPLPQSTLAQLVIQQQHQQFLEK 26 0 Q9UKV0-10;Q9UKV0-3;Q9UKV0-4;Q9UKV0-2;Q9UKV0;Q9UKV0-5;Q9UKV0-7;B7Z3P7;B5MCF1;Q9UKV0-11;Q9UKV0-9;Q9UKV0-8;Q9UKV0-6 Q9UKV0-10 HDAC9 Histone deacetylase 9 1 T(0.048)QS(0.074)APLPQS(0.683)T(0.194)LAQLVIQQQHQQFLEK 130.16 1.7956e-10 5584200.0 12048.0 14292.0 12976.0 20150.0 12831.0 15711.0 18131.0 15406.0 10626.0 13044.0 True False 14087.48844115325 15710.815307462519 13285.39705175404 19021.060827181427 10316.857658104189 14887.087502365192 16413.500422927424 15001.608824006282 10781.385147583018 15408.773943752807 0.9142510943815068 1.019601907641209 0.8621968951099026 1.2344305196905787 0.6695443580238233 0.9661435463138115 1.0652048295887917 0.9735757613660364 0.6996913048980204 1.0 13.911464452587262 -6.2612560818950005 24.999999924415516 0.9063701879034649 0.9980885593108383 0.11528158532178978 0.14923226847930307 47.453218387515236 6472276.157166778 0.04488524710353518 0.05426854369655196 5.479537685101938e-07 6.2612560818950005 0.09171837140737338 TQSAPLPQS(ph)TLAQLVIQQQHQQFLEK ddPTM_PC-9_Lapatinib_30min_R1 1 TQSAPLPQSTLAQLVIQQQHQQFLEK 26 0 Q9UKV0-10;Q9UKV0-3;Q9UKV0-4;Q9UKV0-2;Q9UKV0;Q9UKV0-5;Q9UKV0-7;B7Z3P7;B5MCF1;Q9UKV0-11;Q9UKV0-9;Q9UKV0-8;Q9UKV0-6 Q9UKV0-10 HDAC9 Histone deacetylase 9 1 T(0.041)QS(0.035)APLPQS(0.731)T(0.192)LAQLVIQQQHQQFLEK 114.57 6.9245e-12 5809400.0 56316.0 50872.0 47116.0 38332.0 48456.0 49149.0 42970.0 38713.0 46948.0 47700.0 True False 55512.92351291043 50754.209009566395 43242.30435301953 41151.06315180347 45605.91334816139 47047.01184191488 45194.776346175255 40511.74730875477 41660.22185564294 55944.88144374522 0.992278865917892 0.9072180993108682 0.7729447848861986 0.7355643999922046 0.8151936722579336 0.8409529277351764 0.8078447067873472 0.7241367979211991 0.744665477529592 1.0 15.77171852051823 -5.040343145748204 3.090288706405201 0.7948189117462002 0.9869181311042043 0.38669130626690884 0.07532939686446173 0.23978354801391144 4.3604876038506175 0.018879236613800896 0.08236071539409834 9.112905238741253e-06 5.040343145748204 0.19209921935800411 TQSAS(ph)PPPK ddPTM_PC-9_AZD4547_30min_R2 1 TQSASPPPK 9 0 Q9UN81 Q9UN81 L1RE1 LINE-1 retrotransposable element ORF1 protein 1 T(0.001)QS(0.035)AS(0.964)PPPK 98.902 0.0043132 10846000.0 53318.0 64495.0 60626.0 56810.0 60806.0 63009.0 53245.0 56087.0 62285.0 55993.0 True False 70272.01491670548 85341.7474815344 59822.05962767529 43713.33220575059 52364.136487960895 59069.03726934968 57983.7018507674 47420.04290104245 65577.25794265237 54032.70211294279 1.3005460058210339 1.5794462269006526 1.1071454376394354 0.8090162160385398 0.9691193377393167 1.0932090189729844 1.0731223792873799 0.877617462142128 1.2136586803595049 1.0 15.721545210829351 -5.406141882397666 5.163701582745276 1.0019116554447025 1.4345453549419573 0.6574770607164524 0.12346350523796702 0.12069971070461344 4.5895485603227 0.03169565643888461 0.0677302644514586 3.9251668070572345e-06 5.406141882397666 0.43263369949725483 TQSAS(ph)PPPK ddPTM_PC-9_Lapatinib_30min_R1 1 TQSASPPPK 9 0 Q9UN81 Q9UN81 L1RE1 LINE-1 retrotransposable element ORF1 protein 1 T(0.01)QS(0.014)AS(0.975)PPPK 117.79 0.0018367000000000001 13778000.0 43482.0 85490.0 77624.0 67834.0 84776.0 75463.0 96947.0 91024.0 71339.0 70524.0 True False 42861.938706377776 85292.05315749007 71242.0543573053 72822.73864759052 79789.64235602885 72235.62340284481 101966.44129468575 95253.30733944921 63304.0505870264 82713.97943267682 0.5181946147478527 1.0311685369570645 0.8613060917385938 0.8804163352684893 0.9646451894020144 0.8733181972176707 1.2327594681583303 1.1515986534897464 0.7653367788760703 1.0 16.33584355844789 -4.757259080562422 24.941237549644107 0.976427880541654 0.5181939226840103 0.5118897182019619 0.13332068329895366 103.83636256296404 619442.2853890543 0.03441657811663447 0.25931575414444724 1.7488031200657163e-05 4.757259080562422 -0.45823395785764365 TQSAS(ph)PPPKER ddPTM_PC-9_AZD4547_30min_R2 2 TQSASPPPKER 11 1 Q9UN81 Q9UN81 L1RE1 LINE-1 retrotransposable element ORF1 protein 1 T(0.03)QS(0.431)AS(0.539)PPPKER;T(0.004)QS(0.041)AS(0.955)PPPKER 73.887 0.011145 98834000.0 312360.0 336200.0 410130.0 560150.0 465140.0 419800.0 310330.0 399640.0 367290.0 382890.0 True False 411683.98250838456 444870.07525066903 404691.40822581894 431016.07173123054 400563.3399008336 393549.83963676525 337948.76881113055 337884.82081360347 386704.199562604 369485.1376426463 1.1142098573571084 1.2040269822190588 1.0952846731746568 1.166531553829629 1.084112185016343 1.0651303653176802 0.9146478014441363 0.9144747281835037 1.0466028539870835 1.0 18.495156808279177 -6.883714714189032 2.0349242608241553 0.9631910802667373 1.1425387489601462 0.7135140667647621 0.04875304499399375 0.1636411953400631 1.3851162855339079 0.02001110073815423 0.016899184852802458 1.3070291869439345e-07 6.883714714189032 0.1793476686934089 TQSAS(ph)PPPKER ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TQSASPPPKER 11 1 Q9UN81 Q9UN81 L1RE1 LINE-1 retrotransposable element ORF1 protein 1 T(0.133)QS(0.006)AS(0.861)PPPKER;T(0.024)QS(0.026)AS(0.95)PPPKER;T(0.001)QS(0.005)AS(0.994)PPPKER;T(0.09)QS(0.011)AS(0.898)PPPKER;T(0.006)QS(0.016)AS(0.977)PPPKER 66.215 0.021986000000000002 117226000.0 325573.0 280636.0 320618.0 386152.0 417740.0 377727.0 371440.0 411573.0 371252.0 308011.0 True False 380686.0785401388 308495.6874212887 328262.749070536 364517.1553616745 335886.8457716816 357918.3311696201 336254.51420727785 400769.6448476392 376680.85816021875 363850.95608626516 1.0462692818921224 0.8478627917859523 0.9021901511582353 1.0018309674999215 0.9231440515771144 0.9836949035933316 0.9241545434542036 1.1014665157362429 1.0352614219073586 1.0 18.47298807609861 -7.751355721897237 24.999999999835797 1.0512729810227408 0.9440831803527685 0.3830427019325222 0.05709603840098107 184.82308276831395 458226.9979175278 0.02646070589640864 0.015046503894894646 1.7727368728627176e-08 7.751355721897237 -0.1071898006699723 TQSAS(ph)PPPKER ddPTM_PC-9_Lapatinib_30min_R1 4 TQSASPPPKER 11 1 Q9UN81 Q9UN81 L1RE1 LINE-1 retrotransposable element ORF1 protein 1 TQS(0.007)AS(0.993)PPPKER;T(0.074)QS(0.037)AS(0.889)PPPKER;T(0.206)QS(0.006)AS(0.788)PPPKER;T(0.003)QS(0.009)AS(0.988)PPPKER 97.463 0.0084801 99195900.0 472624.0 371812.6 427814.0 348056.5 412124.6 375245.1 340543.8 333923.5 405527.0 296333.0 True False 465884.2950913727 370951.6907687974 392640.78432979604 373653.7360924466 387884.2412961382 359196.74181205174 358175.4916703895 349438.8048576692 359852.2788713751 347553.7642110968 1.3404668372643618 1.0673217469268703 1.1297267495319496 1.0750962140795495 1.1160409733342596 1.0334997885215917 1.0305613938131346 1.0054237382548603 1.0353859342832736 1.0 18.40687664467871 -1.5228787452803385 0.9377128450336114 1.04474650051761 180.88048980786954 0.8012158421606378 0.04235491357395534 486.6351203383467 0.898432076399408 0.014041693291844261 187620.41004542273 0.029999999999999933 1.5228787452803385 179.83574330735192 TQSEESRPQSLQQPATSTTETPAS(ph)PAHTTPQTQSTSGR ddPTM_PC-9_AZD4547_30min_R2 2 TQSEESRPQSLQQPATSTTETPASPAHTTPQTQSTSGR 38 1 B8ZZU6;E9PBF9;P15336-5;P15336;P15336-4;F5H629;P15336-2 B8ZZU6 ATF2 Cyclic AMP-dependent transcription factor ATF-2 1 TQSEESRPQSLQQPAT(0.002)S(0.008)T(0.008)T(0.008)ET(0.019)PAS(0.933)PAHT(0.006)T(0.003)PQT(0.009)QS(0.001)T(0.001)S(0.001)GR;TQSEESRPQSLQQPAT(0.002)S(0.002)T(0.002)T(0.002)ET(0.002)PAS(0.933)PAHT(0.02)T(0.02)PQT(0.01)QS(0.003)T(0.002)S(0.001)GR 58.566 6.2684e-05 41856000.0 6616.2 3560.7 22129.5 65573.0 39364.0 37964.0 14355.0 48263.0 27150.0 33934.0 True False 8720.013974490903 4711.626641716416 21836.048370841552 50456.15794275097 33898.98807209965 35590.10507853783 15632.567190680187 40805.062323408485 28585.093572176473 32745.980988705727 0.2662926475618026 0.1438841194997787 0.6668314007258762 1.5408351321083824 1.0352106441334465 1.0868541422171185 0.4773888800604858 1.2461090213630301 0.8729344093260065 1.0 14.999030230826573 -5.479000262246958 4.751764442024132 1.0322279790598372 0.2308670544395153 0.6257184820206522 0.2564110998681066 0.1305220204381086 6.690675796852525 0.06978660704206341 0.14472343202058685 3.318942571395518e-06 5.479000262246958 -0.8013609246203219 TQSLPVT(ph)EK ddPTM_PC-9_AZD4547_30min_R2 3 TQSLPVTEK 9 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 T(0.003)QS(0.087)LPVT(0.91)EK;T(0.008)QS(0.219)LPVT(0.773)EK;T(0.165)QS(0.026)LPVT(0.809)EK 149.94 0.0005928999999999999 296916000.0 786650.0 710030.0 786670.0 1001670.0 786920.0 724400.0 708820.0 816690.0 607250.0 602310.0 True False 1036788.3366635342 939533.3121065813 776238.2417989525 770750.4571472312 677669.7412279394 679103.1534846922 771903.6068337113 690489.3261692068 639347.9952745549 581223.3102288968 1.7838037780267746 1.6164756223155867 1.335524966287493 1.3260831828023123 1.1659369631287846 1.168403161974437 1.3280671873427117 1.1879931758023934 1.1000040501176176 1.0 19.148733038517783 -1.5228787453007653 0.4028327811046522 1.1256907353820427 12.736959662922109 0.8882945815867915 0.0758306489665385 23.33223408505451 0.30808662132300957 0.05600230271872127 215.49128365371547 0.029999999998588902 1.5228787453007653 11.611268927540067 TQSLPVT(ph)EK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TQSLPVTEK 9 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 TQS(0.01)LPVT(0.99)EK;T(0.06)QS(0.243)LPVT(0.698)EK 140.78 0.0018468 72001000.0 368208.0 352592.0 213148.0 291101.0 273290.0 211797.0 220964.0 234579.0 185658.0 154532.0 True False 430538.3419605033 387595.0035606503 218230.25668829185 274791.5547321755 219740.7863286805 200689.99247269053 200032.69027917585 228421.54980699503 188372.8970195715 182547.42832536128 2.3585012723002503 2.123256444181864 1.1954715478069167 1.5053159458505434 1.2037462721032042 1.0993854819745423 1.095784761879252 1.2512997411273883 1.03191208305508 1.0 17.4779118190881 -5.008977307680968 1.1149522400451712 1.1373058969686498 2.783191198748588 0.8916523439727857 0.14837684015627164 0.33881547625423414 0.4568104901049157 0.0460738036371509 0.5991125088406408 9.795411660726563e-06 5.008977307680968 1.645885301779938 up TQSLPVT(ph)EK ddPTM_PC-9_Lapatinib_30min_R1 1 TQSLPVTEK 9 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 TQS(0.023)LPVT(0.977)EK 157.97 0.0002673 94136000.0 258270.0 308250.0 206960.0 212480.0 214130.0 221380.0 235240.0 222660.0 194520.0 217620.0 True False 254587.0224390831 307536.266063824 189944.54768870297 228106.48801250078 201535.29439577783 211912.0934619852 247419.57616183985 233005.5964602936 172611.109213591 255235.3270395771 0.9974599730843942 1.2049126178216587 0.7441937990788005 0.8937104853715266 0.7896057992180978 0.8302616096286932 0.9693782558692382 0.9129049617185769 0.6762822028426563 1.0 17.96146850031679 -5.260926714280588 24.999998687943336 0.8516025868417875 1.1011862994432506 0.4755775413489185 0.10464951554065019 35.41912890641294 1727092.2686723962 0.025892738246632387 0.060540490854005195 5.483694926039565e-06 5.260926714280588 0.24958371260146317 TQSLS(ph)ALPK ddPTM_PC-9_AZD4547_30min_R2 1 TQSLSALPK 9 0 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 T(0.01)QS(0.354)LS(0.636)ALPK 95.48299999999999 0.005411600000000001 67382000.0 100530.0 90531.0 123780.0 149550.0 150630.0 130130.0 94727.0 132770.0 113810.0 118500.0 True False 132496.44884610077 119793.37531980463 122138.59632358466 115073.55802446736 129717.6245630621 121992.95052866207 103157.5194894855 112253.44725108161 119825.76425227994 114351.35106859305 1.1586784730389716 1.0475903800030069 1.0680992850737765 1.0063156836287932 1.1343777170175424 1.0668256158642606 0.9021101939373415 0.981653878175405 1.0478736204909647 1.0 16.803113885822114 -7.088807474904358 9.902412539352133 0.9815508215597982 1.0784007342374422 0.45974225986537776 0.05184629229231093 0.4541111002803565 48.26942305886863 0.019791781536105453 0.015333226840402748 8.150655269063237e-08 7.088807474904358 0.09684991267764398 TQSLS(ph)ALPK ddPTM_PC-9_Lapatinib_30min_R1 1 TQSLSALPK 9 0 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 TQS(0.03)LS(0.97)ALPK 123.01 0.0015220000000000001 56806000.0 255030.0 264490.0 313170.0 260040.0 318390.0 392930.0 391440.0 346570.0 383710.0 316020.0 True False 251393.22543322624 263877.58965521684 287422.3714711589 279164.20906801097 299662.9261788242 376125.2998645678 411706.8478693697 362672.90741598763 340492.5391545705 370643.63592981896 0.6782612759627346 0.7119442075222406 0.7754682493066793 0.7531876498234829 0.8084933805137966 1.0147895806196623 1.1107889302794505 0.9784948998413652 0.9186520586017628 1.0 18.49967321450047 -6.650496761006975 3.2243700299537825 1.0111596670957836 0.734862865604469 0.8689563288745308 0.050917331389683865 0.09203060537634591 1.898731351894889 0.019681261158536852 0.019469763288520826 2.2361618760831876e-07 6.650496761006975 -0.27629680149131464 TQSPHS(ph)PKEESER ddPTM_PC-9_AZD4547_30min_R2 1 TQSPHSPKEESER 13 1 Q5T5U3;E7ESW5;A0A1B0GV73;Q5T5U3-3;A0A1B0GTZ9 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 T(0.082)QS(0.196)PHS(0.722)PKEES(0.001)ER 64.327 0.019964 3763400.0 2847.6 2771.7 4527.0 7382.9 7221.8 4420.1 3572.8 4948.5 4414.7 4799.6 True False 3753.077566240485 3667.5978214523507 4466.969022110744 5680.886469667946 6219.17772734197 4143.71044825743 3890.772278569289 4183.8230302174925 4648.052029211325 4631.567464884544 0.8103255743752923 0.7918696746315832 0.9644616117498563 1.2265580740729982 1.3427803382967676 0.8946669739076605 0.840055188242039 0.9033276664840262 1.0035591761216398 1.0 12.17728481316127 -5.356899935387782 4.3121409706347995 1.0295974498140752 0.8010785207485998 0.2777745925097168 0.14484053183268283 0.31999164537508534 10.232470492289062 0.044331019470468754 0.09913958045978993 4.39642900695814e-06 5.356899935387782 -0.22851892906547544 TQSRPGGPPNPPGPS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 TQSRPGGPPNPPGPSPK 17 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785;O95785-2 B9EGQ5 WIZ Protein Wiz 1 TQSRPGGPPNPPGPS(1)PK 55.336999999999996 0.024803 6544000.0 25073.0 17994.0 18023.0 35499.0 33212.0 27442.0 21786.0 26456.0 23059.0 25169.0 True False 33045.69244920201 23810.20860815153 17784.003243981006 27315.254004082726 28601.087080849873 25726.04740188692 23724.911794925694 22367.833098400322 24277.8516641185 24287.84097084736 1.3605858375335496 0.9803345071606352 0.7322183666027419 1.1246472684364643 1.1775887002545715 1.0592150793792596 0.9768225929757467 0.9209477748659661 0.9995887116215538 1.0 14.567946629132488 -4.759839336757563 24.975607048930055 0.9970477550844608 1.360586291865498 0.47931887487537983 0.11374129907190633 39.02558154649729 608968.6017298348 0.03058726922689915 0.18854375036901358 1.7384438310847234e-05 4.759839336757563 0.3635385367810373 TQSRPGGPPNPPGPS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TQSRPGGPPNPPGPSPK 17 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785;O95785-2 B9EGQ5 WIZ Protein Wiz 1 TQSRPGGPPNPPGPS(1)PK;T(0.001)QS(0.001)RPGGPPNPPGPS(0.997)PK;TQSRPGGPPNPPGPS(1)PK 66.76 0.0092934 17597700.0 57702.0 52823.0 49557.0 67336.0 60556.0 55977.0 64766.0 58873.0 59151.0 53099.0 True False 67469.80893355132 58066.91834495472 50738.62682596911 63563.38222625744 48690.486504883294 53041.46757812336 58630.89561476572 57327.64613109969 60015.971472302204 62725.4283685473 1.0756372764348154 0.9257317144775608 0.808900443498784 1.0133590774826868 0.7762479710588694 0.845613476985359 0.9347229208268792 0.9139458688790041 0.9568044895552485 1.0 15.936762797763707 -10.357042116320581 18.78962336821927 0.9999999999999939 0.9109238585531025 0.07476518462212478 0.08563593565169504 0.0 0.0 0.08227166958359161 0.019953810805239062 4.3949899233581104e-11 10.357042116320581 -0.08907614144689135 TQSRPGGPPNPPGPS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 TQSRPGGPPNPPGPSPK 17 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785;O95785-2 B9EGQ5 WIZ Protein Wiz 1 TQSRPGGPPNPPGPS(1)PK;TQSRPGGPPNPPGPS(1)PK 61.703 0.014761000000000002 15642100.0 37624.0 29006.0 21705.4 23980.0 25654.0 24180.7 25032.0 20270.8 22103.4 19969.3 True False 37087.474860603426 28938.838389123317 19920.865797266964 25743.569194934982 24145.08215770458 23146.54782896481 26328.03447748333 21212.65537019364 19613.882332879333 23420.966897580332 1.5835159591312606 1.2355953755313598 0.8505569340659898 1.0991676521089573 1.0309173939441012 0.9882831878882048 1.1241224409143984 0.9057121963818309 0.8374497269327374 1.0 14.515513016001297 -4.9051814475656235 2.935976461352422 0.9882272170834476 1.6124883004390818 0.8053249025222664 0.09223833798111615 0.13178892974995274 1.9276832718762826 0.02426303080099634 0.17093791053784102 1.2439947640867751e-05 4.9051814475656235 0.6242610833556341 TQSS(ph)ASLAASYAAQQHPQAAASYR ddPTM_PC-9_AZD4547_30min_R2 2 TQSSASLAASYAAQQHPQAAASYR 24 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 T(0.269)QS(0.269)S(0.449)AS(0.012)LAASYAAQQHPQAAASYR;T(0.241)QS(0.241)S(0.378)AS(0.141)LAASYAAQQHPQAAASYR 151.98 4.4723999999999996e-09 26752000.0 4158.0 5579.2 20420.5 35090.0 32020.0 26616.5 16054.199999999999 24131.0 20321.4 29410.3 True False 5480.1575082272575 7382.567292797545 20149.710827482326 27000.542635095713 27574.575705432137 24952.166047384413 17482.992698893606 20402.10842521537 21395.547717039655 28380.65434879861 0.19309482582311355 0.26012674697579896 0.709980488111448 0.9513713920496227 0.9715976018924809 0.8791962912736955 0.6160179565991467 0.7188737854481153 0.753877886467595 1.0 14.792620232333533 -5.293978868273324 3.2962253480334742 0.827861302009362 0.20297364978478138 0.816708614181937 0.11484811149990659 0.10435989444677761 2.3203009838750415 0.03413477297291605 0.09092921897824544 5.081841689804188e-06 5.293978868273324 -0.6248876522245806 down TQSS(ph)ASLAASYAAQQHPQAAASYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TQSSASLAASYAAQQHPQAAASYR 24 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 T(0.274)QS(0.274)S(0.442)AS(0.01)LAASYAAQQHPQAAASYR;T(0.248)QS(0.248)S(0.454)AS(0.051)LAASYAAQQHPQAAASYR 193.29 6.6296e-25 15705700.0 10542.2 14828.9 23174.0 26093.0 35834.0 40061.0 34678.0 32646.0 36761.0 30630.0 True False 12326.786242058912 16301.015191214032 23726.556047884416 24631.093804647386 28812.58493652137 37960.13063664006 31393.04879302173 31789.07709129621 37298.56008002062 36182.9765330534 0.34067916526431447 0.450516147457436 0.6557380934708354 0.6807370803821712 0.7963022309732002 1.0491157520433185 0.8676193005941334 0.8785644559191162 1.0308317240276827 1.0 15.143023473325117 -5.2889676878799445 0.567564340897026 0.9803493369925198 0.10730365803149826 0.9149770010324427 0.0670019351654553 0.6591416940945162 0.24073907768027328 0.041521337501340766 0.35239747431868573 5.140818985756274e-06 5.2889676878799445 -0.8730456789610216 down TQSS(ph)ASLAASYAAQQHPQAAASYR ddPTM_PC-9_Lapatinib_30min_R1 2 TQSSASLAASYAAQQHPQAAASYR 24 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 T(0.089)QS(0.221)S(0.589)AS(0.101)LAASYAAQQHPQAAASYR;T(0.265)QS(0.265)S(0.459)AS(0.011)LAASYAAQQHPQAAASYR 163.52 4.8593e-10 23143000.0 34488.0 21904.8 31029.0 26079.0 36479.0 46566.0 37673.0 34907.0 46105.0 31873.0 True False 33996.19479567537 21854.080781426892 28477.915395403747 27996.93665699371 34333.376940473405 44574.48073064779 39623.5236045953 36528.90665426868 40912.16939282653 37382.205581897106 0.9094218563748561 0.5846118612115829 0.761804044253467 0.748937528462784 0.9184417132706546 1.1923983627181605 1.059956816025419 0.9771736601854853 1.0944289871606416 1.0 15.190064071377131 -6.4390753152120865 3.3371771941588912 1.0633696380659068 0.7401846167545445 0.7184173740001143 0.09199413279191562 0.1283013003489417 2.737356416681698 0.029686542434955634 0.0332304306331032 3.6385193156835575e-07 6.4390753152120865 -0.3231850213113623 TQSS(ph)LTVSEVLTR ddPTM_PC-9_Lapatinib_30min_R1 1 TQSSLTVSEVLTR 13 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 T(0.006)QS(0.266)S(0.727)LT(0.001)VSEVLTR 200.81 3.2946999999999995e-07 12617000.0 20688.0 24688.0 27172.0 21776.0 21475.0 28630.0 25318.0 17933.0 19865.0 21053.0 True False 20392.985326285456 24630.836452826188 24938.023046953196 23377.47968260649 20211.882721474452 27405.56163978968 26628.842158074578 18766.232647635145 17627.5945122763 24691.982998640826 0.8258950011187028 0.9975236275750715 1.0099643697440548 0.9467639631816248 0.818560531269887 1.109897153310782 1.0784408105068097 0.7600131851973223 0.7138995079190932 1.0 14.591755082673524 -7.775557432214882 24.999999148799187 0.8027172151723463 0.9709171618339868 0.2520929028558322 0.11250310111209468 299.68897364992205 530676.144110773 0.061088399789734224 0.02957247380754966 1.6766505965170325e-08 7.775557432214882 0.1681999466616405 TQSSS(ph)CEDLPSTTQPK ddPTM_PC-9_AZD4547_30min_R2 2 TQSSSCEDLPSTTQPK 16 0 Q5JS72;A0A2U3TZM4;A0A2R8Y6F8;A0A2R8YFN5;O14936-5;O14936-3;O14936-4 Q5JS72 CASK Peripheral plasma membrane protein CASK 1 T(0.004)QS(0.024)S(0.089)S(0.841)CEDLPS(0.038)T(0.004)TQPK;TQSS(0.088)S(0.912)CEDLPSTTQPK 244.27 7.0655e-47 26500000.0 67746.0 98299.0 101592.0 120375.0 119980.0 98460.0 90885.0 120866.0 99498.0 96333.0 True False 89287.81879566213 130072.22940828525 100244.8237009663 92624.40352521084 103322.84800555102 92303.28063515015 98973.58893242528 102188.93692437459 104757.26115080717 92960.41099148308 0.960492943645038 1.3992217549490213 1.0783603754737123 0.9963854778320309 1.111471506026553 0.9929310730307213 1.0646853631218682 1.0992737213020392 1.1269018718129904 1.0 16.504328826670374 -5.492282504384677 24.998067719743734 1.0583866804704065 1.1945907952438601 0.16632988747312527 0.10836834297145966 952.304749882491 778060.7449345959 0.026171933486399287 0.054364543166930165 3.2189741983358712e-06 5.492282504384677 0.13620411477345362 TQSSS(ph)CEDLPSTTQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TQSSSCEDLPSTTQPK 16 0 Q5JS72;A0A2U3TZM4;A0A2R8Y6F8;A0A2R8YFN5;O14936-5;O14936-3;O14936-4 Q5JS72 CASK Peripheral plasma membrane protein CASK 1 T(0.001)QS(0.003)S(0.331)S(0.662)CEDLPS(0.003)T(0.001)T(0.001)QPK;T(0.003)QS(0.002)S(0.055)S(0.939)CEDLPSTTQPK 161.26 3.0726e-05 20880000.0 129843.0 147240.0 146117.0 154239.0 216915.0 138553.0 145101.0 138003.0 136548.0 133151.0 True False 151822.85538385273 161857.01412473965 149600.98343180842 145597.48887958514 174412.06288735647 131287.0367713834 131355.98283973278 134380.56747626487 138544.75617656362 157290.2222772641 0.9652402621456422 1.0290341750514245 0.9511143239921077 0.9256614096643112 1.1088550856003672 0.8346802164215683 0.8351185530667277 0.8543478770052525 0.880822432384533 1.0 17.263069464894535 -6.790173401031936 24.999974069588802 0.8690233202757353 0.9914181899900076 0.4361141819848364 0.06455891922975139 186.2056686998 162006.54438599266 0.02188592128592935 0.019304916619931257 1.6211626854724743e-07 6.790173401031936 0.12239486971427238 TQSSS(ph)CEDLPSTTQPK ddPTM_PC-9_Lapatinib_30min_R1 1 TQSSSCEDLPSTTQPK 16 0 Q5JS72;A0A2U3TZM4;A0A2R8Y6F8;A0A2R8YFN5;O14936-5;O14936-3;O14936-4 Q5JS72 CASK Peripheral plasma membrane protein CASK 1 TQSS(0.021)S(0.976)CEDLPS(0.003)TTQPK 292.45 1.6553999999999999e-111 11906000.0 50486.0 67107.0 51235.0 33072.0 47636.0 41096.0 34366.0 36397.0 44925.0 35904.0 True False 49766.060382001466 66951.61786454185 47022.65607281932 35504.225204957846 44834.14413597936 39338.419879455025 36145.30332587059 38088.13749378108 39865.073418777385 42109.95856092723 1.1818121433198971 1.5899236226431381 1.1166635560750815 0.8431313261348427 1.0646921932043845 0.9341832959188935 0.8583552337999426 0.9044924002637729 0.9466899227910232 1.0 15.361873835346787 -5.4941026852527495 5.390124280075641 0.9360523297361931 1.3836890568667348 0.7269346682172564 0.1096712195900879 0.08267608815674145 6.826712963510939 0.02742587209598646 0.055334559953577576 3.2055113188891053e-06 5.4941026852527495 0.4476367271305417 TQSSSCEDLPS(ph)TTQPK ddPTM_PC-9_Lapatinib_30min_R1 1 TQSSSCEDLPSTTQPK 16 0 Q5JS72;A0A2U3TZM4;A0A2R8Y6F8;A0A2R8YFN5;O14936-5;O14936-3;O14936-4 Q5JS72 CASK Peripheral plasma membrane protein CASK 1 TQSSS(0.001)CEDLPS(0.998)TTQPK 293.38 1.4973999999999997e-111 10185000.0 50104.0 68948.0 46496.0 31688.0 47469.0 40608.0 33823.0 36878.0 49252.0 35356.0 True False 49389.50777205174 68788.35514215245 42673.278359750344 34018.441228069176 44676.96674764473 38871.29050187145 35574.18944278997 38591.48650975794 43704.721113447355 41467.23749109133 1.1910489041538492 1.6588603269492135 1.02908418649586 0.8203691223795069 1.077403980847361 0.9373976385627911 0.8578866496817541 0.9306500467519399 1.0539578654796264 1.0 15.339684318988796 -5.398598593326305 6.133960727054897 0.9497936894230161 1.420619210961614 0.6753276279105402 0.12874843631374772 0.11313655363780004 5.142025062279077 0.03145420619434461 0.06638075274441017 3.993938808070755e-06 5.398598593326305 0.4708255215385979 TQSSSCERDS(ph)PSTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TQSSSCERDSPSTSR 15 1 Q5JS79;A0A2U3TZM1;A0A2R8YE77;A0A2R8YEK3;O14936-6;O14936-2;O14936 Q5JS79 CASK Peripheral plasma membrane protein CASK 1 T(0.001)QS(0.005)S(0.005)S(0.003)CERDS(0.985)PS(0.002)TSR;TQSSS(0.002)CERDS(0.936)PS(0.045)T(0.016)S(0.001)R 86.179 0.0026226 22018000.0 26861.0 28481.0 30699.0 31636.0 37866.0 24868.6 25344.9 26908.7 24418.3 26006.6 True False 31408.036771067196 31308.40545562833 31430.980586605834 29863.537485295856 30446.429123355403 23564.446837331743 22944.047590814247 26202.375137124352 24775.37144261495 30721.39071186766 1.0223507479085014 1.0191076878408993 1.0230975830942464 0.9720763544001796 0.991049832636449 0.7670371129464789 0.746842739184687 0.8529032875781364 0.8064534472081771 1.0 14.906955905755046 -6.718192239361765 8.28774476018723 0.8200619288004272 1.0059754912538645 0.6211051034534469 0.06625697976394163 0.1547525464003767 26.454142752719296 0.021159102142574836 0.021022108124242326 1.913408771952092e-07 6.718192239361765 0.18591356245343738 TQSSSCERDS(ph)PSTSR ddPTM_PC-9_Lapatinib_30min_R1 2 TQSSSCERDSPSTSR 15 1 Q5JS79;A0A2U3TZM1;A0A2R8YE77;A0A2R8YEK3;O14936-6;O14936-2;O14936 Q5JS79 CASK Peripheral plasma membrane protein CASK 1 TQS(0.001)S(0.001)SCERDS(0.983)PS(0.013)T(0.001)SR;TQSSSCERDS(0.999)PSTSR 84.436 0.0028811 24443000.0 34451.0 31041.0 22851.0 20893.7 22720.0 22147.0 19761.2 21656.0 32171.0 21030.7 True False 33959.72242246034 30969.126471653355 20972.27898741085 22430.29239733999 21383.65426923864 21199.82443717856 20784.338243705788 22662.216819114852 28547.56320435142 24665.82847335373 1.3767922881303873 1.2555477917601277 0.8502564189184649 0.9093670793004675 0.8669343619387935 0.8594815479269442 0.8426369406630279 0.9187697402338072 1.1573729718906904 1.0 14.590226124790876 -5.1518724027978955 4.068975694923731 0.9148660227631484 1.3504740047324835 0.7477502488050944 0.09142455944579951 0.10647666508458058 2.992817358967706 0.02417152614508683 0.07332271224065337 7.0490014061535925e-06 5.1518724027978955 0.43560798196933503 TQT(ph)PPLGQTPQLGLK ddPTM_PC-9_AZD4547_30min_R2 3 TQTPPLGQTPQLGLK 15 0 H0Y3P2;D3DQV9;P78344-2;P78344;E9PKF8 H0Y3P2 EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 1 T(0.006)QT(0.618)PPLGQT(0.376)PQLGLK;T(0.096)QT(0.884)PPLGQT(0.021)PQLGLK;T(0.006)QT(0.985)PPLGQT(0.009)PQLGLK 132.17 1.8194000000000002e-05 485176000.0 704894.0 681330.0 886620.0 900412.0 811449.0 870632.0 961192.0 963444.0 858112.0 1000551.0 True False 929035.6292939761 901556.5983656698 874862.8394927839 692835.9246267249 698793.3129793016 816191.243407903 1046736.225924365 814565.867540641 903470.0484496302 965522.0140340235 0.9622107168871225 0.9337504326793116 0.9061034619371766 0.717576517734696 0.7237466394574378 0.8453367520827357 1.0841143036718783 0.8436533353986654 0.9357322104701316 1.0 19.880949627632056 -7.0655481066691825 24.999445614830588 0.9545433030735121 0.8428332942322998 0.27056847449552013 0.0937530257061625 318.43473742405087 121446.72832089977 0.03912382622576988 0.030305202002886656 8.599078098836032e-08 7.0655481066691825 -0.1117100088412123 TQT(ph)PPLGQTPQLGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TQTPPLGQTPQLGLK 15 0 H0Y3P2;D3DQV9;P78344-2;P78344;E9PKF8 H0Y3P2 EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 1 T(0.075)QT(0.811)PPLGQT(0.114)PQLGLK;T(0.286)QT(0.714)PPLGQTPQLGLK;T(0.001)QT(0.999)PPLGQTPQLGLK 145.94 0.00027938 266438000.0 485815.0 394015.0 406336.0 476034.0 483510.0 398658.0 438177.0 440952.0 305022.0 296596.0 True False 568053.8842163737 433130.20524558146 416024.5912778613 449363.3583030516 388769.6864055771 377751.6726827 396669.70243324013 429377.47722726443 309482.36970507004 350366.5069473566 1.6213133189175672 1.2362203482842047 1.187398290157826 1.2825522685322472 1.1096085918509062 1.0781614828824322 1.1321564549343202 1.2255094842492447 0.8833103723341069 1.0 18.418505342496758 -1.5228787452803376 0.5698646588235602 1.0841896058923224 26.156431122449185 0.7097402047727969 0.10056300467178678 84.03441935548425 0.7216062902434703 0.047102610248158414 2597.931306752073 0.029999999999999995 1.5228787452803376 25.07224151655686 TQT(ph)PPLGQTPQLGLK ddPTM_PC-9_Lapatinib_30min_R1 3 TQTPPLGQTPQLGLK 15 0 H0Y3P2;D3DQV9;P78344-2;P78344;E9PKF8 H0Y3P2 EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 1 T(0.043)QT(0.957)PPLGQTPQLGLK;T(0.003)QT(0.997)PPLGQTPQLGLK;T(0.011)QT(0.989)PPLGQTPQLGLK 181.86 2.6145e-05 474956000.0 744225.0 906348.0 848756.0 706589.0 757275.0 682020.0 592995.0 647373.0 613757.0 457431.0 True False 733612.2150258509 904249.4068918566 778974.5579729052 758553.9121718052 712733.5733599332 652851.5944662719 623697.3795531811 677452.3129313296 544629.2235122663 536497.338861505 1.3674107248745002 1.6854685781121563 1.4519635076400534 1.413900605325506 1.3284941447657823 1.2168776006451048 1.1625358307959595 1.2627319165626125 1.015157362509976 1.0 19.033211489368597 -6.773008660241007 0.4704756503500602 1.0160749020984488 1.5853926852342664 0.7794700230197249 0.09243337753181258 0.5110889938923968 0.23912867517270256 0.08490049155499964 0.11944674421583204 1.6865193942682648e-07 6.773008660241007 0.5693177831358176 TQT(ph)PPVEENVTQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQTPPVEENVTQK 13 0 Q6P1Q9-2;Q6P1Q9 Q6P1Q9-2 METTL2B Methyltransferase-like protein 2B 1 T(0.027)QT(0.973)PPVEENVTQK 134.02 0.00010946 11131000.0 14987.0 14198.0 12881.0 15112.0 15004.0 15564.0 16979.0 15820.0 15981.0 12614.0 True False 17524.003093257284 15607.483608686878 13188.13189146453 14265.323633765036 12064.073907115207 14747.7964411439 15370.626202685164 15404.741762675536 16214.691891918334 14900.818347630948 1.1760429987419712 1.0474245940437414 0.885060913017659 0.9573516904212883 0.8096249229850689 0.9897306374108389 1.0315289968707597 1.03381850602351 1.0881745897195154 1.0 13.863103944709941 -9.474559879397598 11.153024637496397 0.9999983535016445 0.9944357002492841 0.0 0.09747725891420649 0.0 0.0 0.10084554046075954 0.024458636187777123 3.353050702692356e-10 9.474559879397598 -0.005562653252360383 TQT(ph)PPVEENVTQK ddPTM_PC-9_Lapatinib_30min_R1 1 TQTPPVEENVTQK 13 0 Q6P1Q9-2;Q6P1Q9 Q6P1Q9-2 METTL2B Methyltransferase-like protein 2B 1 T(0.024)QT(0.976)PPVEENVTQK 142.19 0.00019674 11783000.0 25676.0 26426.0 24438.0 26936.0 26643.0 22093.0 24193.0 22164.0 25134.0 20774.0 True False 25309.855531598256 26364.812220608612 22428.801973408004 28916.963295861886 25075.911122153386 21148.133891298417 25445.595162741858 23193.820353660038 22303.14424724654 24364.758220384978 1.038789521433566 1.082087988812886 0.9205427679821079 1.1868356350718172 1.029187767649318 0.8679804535718584 1.0443606676733852 0.9519413303373039 0.9153854122215925 1.0 14.572508285807062 -6.539785073413357 24.872690364434764 0.9573596296055389 1.0564638756909313 0.29650401963568296 0.0745704585941274 290.8134239150535 427843.21944322606 0.02383390504281029 0.023838737369044263 2.885459125343565e-07 6.539785073413357 0.09910424608539237 TQT(ph)PPVS(ph)PAPQPTEER ddPTM_PC-9_Lapatinib_30min_R1 1 TQTPPVSPAPQPTEER 16 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 T(0.059)QT(0.941)PPVS(0.975)PAPQPT(0.025)EER 117.53 0.0037588 70864000.0 22155.0 56945.0 57269.0 57253.0 67686.0 77835.0 89417.0 104450.0 85945.0 80379.0 True False 21839.06563727058 56813.14735119039 52560.563884732925 61463.57661040919 63704.84255579602 74506.17849224694 94046.57473925872 109303.12831347185 76264.9690590278 94272.4030517148 0.23165915931187597 0.602648765832611 0.5575392393031489 0.6519784647548684 0.6757528236640961 0.7903286230157435 0.9976045130372649 1.159439292679446 0.8089850962767046 1.0 16.524547883139498 -5.824919254313002 0.44798602855152425 1.0447275194252488 0.19709105135475158 0.787168782019811 0.11662304200575836 0.9757753108210555 0.29409205229540536 0.10090491270645738 0.40319860159156673 1.496513867798349e-06 5.824919254313002 -0.8476364680704972 down TQT(ph)PPVS(ph)PAPQPTEERLPSSPVYEDAASFK ddPTM_PC-9_AZD4547_30min_R2 4 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 T(0.076)QT(0.669)PPVS(0.804)PAPQPT(0.243)EERLPS(0.083)S(0.083)PVY(0.041)EDAAS(0.002)FK;T(0.082)QT(0.887)PPVS(0.804)PAPQPT(0.192)EERLPS(0.01)S(0.009)PVY(0.01)EDAAS(0.007)FK;T(0.22)QT(0.712)PPVS(0.695)PAPQPT(0.325)EERLPS(0.014)S(0.013)PVY(0.02)EDAAS(0.001)FK;T(0.423)QT(0.575)PPVS(0.974)PAPQPT(0.014)EERLPS(0.005)S(0.005)PVY(0.004)EDAASFK 54.769 0.0080115 30367700.0 89705.6 79942.1 113855.0 170370.0 155794.0 127053.0 105938.0 118556.0 109339.0 120113.0 True False 118230.11480760734 105781.82047203007 112345.2083084646 131093.82869026088 134164.6923001904 119108.35582508349 115366.27677090041 100235.89434585541 115118.43632000737 115907.880429552 1.0200351724960304 0.9126370017293477 0.969262899917726 1.131017392470901 1.1575113944192497 1.0276122329531918 0.9953272921854458 0.8647892962444266 0.9931890385138702 1.0 16.82261913111892 -10.698816293986136 5.794449641134508 0.9999998655312524 1.0080089021384517 0.0008131584992839835 0.08336687881095692 1.6298483916866215e-07 2.324759143401677e-08 0.09085308378862451 0.02203473957821125 2.0007079876026055e-11 10.698816293986136 0.008009036607199316 TQT(ph)PPVSPAPQPT(ph)EER ddPTM_PC-9_AZD4547_30min_R2 1 TQTPPVSPAPQPTEER 16 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 T(0.011)QT(0.989)PPVS(0.315)PAPQPT(0.685)EER 141.18 0.00011742 36957000.0 61696.0 104570.0 84069.0 62534.0 79828.0 91786.0 82012.0 110540.0 118640.0 74909.0 True False 81314.04464347972 138370.20752219658 82954.19013029123 48117.752440669 68745.26013158131 86046.60691019584 89310.9091217042 93458.58295650044 124911.0681916397 72286.45871052492 1.124886266307584 1.9141926439681827 1.1475757923414927 0.6656537517401312 0.951011591353167 1.1903558210642768 1.235513687001249 1.2928919831411363 1.7280009343361653 1.0 16.14143779462521 -7.803819908239326 3.113177543686993 1.398678294925888 1.1717643145969157 0.04706709344735416 0.33653492771042975 0.7962999886378769 15.54516600978217 0.22242046502140728 0.09967711593516163 1.57101413208337e-08 7.803819908239326 -0.22691398032897236 TQT(ph)PPVSPAPQPT(ph)EER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TQTPPVSPAPQPTEER 16 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 T(0.02)QT(0.98)PPVS(0.418)PAPQPT(0.583)EER;T(0.167)QT(0.833)PPVS(0.045)PAPQPT(0.955)EER 154.07 5.7612e-07 17113000.0 98075.7 182067.0 162857.0 122569.2 162690.0 119759.3 155928.0 124552.9 117192.5 123527.4 True False 114677.97892662774 200141.40852111572 166740.1285186118 115702.04509870776 130812.06237993711 113478.91148380132 141157.3710190404 121283.51834970625 118906.21860607223 145921.93977763993 0.7858857900421099 1.3715648848014013 1.1426666118384612 0.7929036940916347 0.8964523263552576 0.7776686059459171 0.9673485099919867 0.8311534134930059 0.8148618280929171 1.0 17.154837287293475 -5.754133842607675 24.983285347189423 0.8630744953898363 1.1271917555892634 0.330645490816743 0.14924636260643165 162.66522144080204 556271.7866138538 0.03857055923438323 0.06509965899254472 1.761433117262988e-06 5.754133842607675 0.26411726019942716 TQT(ph)PPVSPAPQPT(ph)EER ddPTM_PC-9_Lapatinib_30min_R1 1 TQTPPVSPAPQPTEER 16 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 T(0.078)QT(0.919)PPVS(0.21)PAPQPT(0.793)EER 138.28 7.7949e-05 7339700.0 1702.0 9165.0 7454.6 7718.0 10364.0 10954.0 16963.0 12963.0 11134.0 10293.0 True False 1677.7291678914269 9143.779005595921 6841.711563588155 8285.607466493251 9754.409896407971 10485.522955021179 17841.261139403556 13565.308303758111 9879.971673782245 12072.131335439617 0.13897539061443046 0.7574287216999485 0.5667360115196268 0.686341726764483 0.8080105844916039 0.8685726375622916 1.4778882571487408 1.123687932712846 0.8184115463338321 1.0 13.559392786016804 -6.131038820965335 0.8174178072611142 1.1091782903711864 0.405486744710115 0.5898838381301974 0.21330843406379282 0.5174903906453214 0.7216623288499951 0.11335745123831197 0.22745968311832637 7.395391657505945e-07 6.131038820965335 -0.7036915456610715 TQT(ph)PPVSPAPQPT(ph)EERLPSSPVYEDAASFK ddPTM_PC-9_Lapatinib_30min_R1 2 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 T(0.281)QT(0.582)PPVS(0.285)PAPQPT(0.409)EERLPS(0.103)S(0.096)PVY(0.165)EDAAS(0.079)FK;T(0.376)QT(0.62)PPVS(0.239)PAPQPT(0.387)EERLPS(0.103)S(0.11)PVY(0.155)EDAAS(0.01)FK 46.983000000000004 0.03207 17968200.0 42995.0 38110.0 41034.0 39989.0 44395.0 56050.0 44297.0 40305.0 53788.0 41765.0 True False 42381.88341568265 38021.758636471444 37660.34291582063 42929.924459393435 41783.773383928194 53652.872158931605 46590.481913114396 42177.71744063652 47729.82902724978 48984.02460163564 0.8652184821552508 0.7762073236261164 0.7688290870767507 0.8764066409104316 0.8530081740676935 1.0953136781892778 0.9511362590561552 0.8610504707126118 0.9743958242593244 1.0 15.580023692330244 -6.544954303825812 24.929227373995563 0.9670110175471747 0.8209022221327689 0.5880256103610526 0.06232009568143992 178.6145009408201 201702.20579344983 0.02164009808351047 0.021641661342859428 2.8513182655169026e-07 6.544954303825812 -0.1461087954144058 TQT(ph)PPVSPAPQPTEER ddPTM_PC-9_AZD4547_30min_R2 3 TQTPPVSPAPQPTEER 16 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 T(0.02)QT(0.98)PPVSPAPQPTEER;T(0.405)QT(0.586)PPVS(0.009)PAPQPTEER;T(0.003)QT(0.523)PPVS(0.466)PAPQPT(0.008)EER 171.29 6.0038000000000004e-05 679634000.0 756861.0 934388.0 913639.0 597930.0 728802.0 972142.0 881749.0 869730.0 900369.0 668882.0 True False 997527.0543132265 1236410.6480467662 901523.5498988813 460086.47642641125 627620.4223382387 911353.8070608977 960222.9528258501 735333.2129071561 947960.6672002559 645464.6447718344 1.5454402691038838 1.9155358206859272 1.3967047726023187 0.7127988808574441 0.9723544541468984 1.4119345101900238 1.4876460865881815 1.139230814364882 1.4686484765332903 1.0 19.29997854873107 -5.516307092987544 24.97644231564782 1.1807118894091166 1.7118961981657985 0.4539693454070085 0.24423134997491278 265.34739924471415 1008486.3636533803 0.06985985641546535 0.12698275882764712 3.045740561300725e-06 5.516307092987544 0.5311843087566819 TQT(ph)PPVSPAPQPTEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TQTPPVSPAPQPTEER 16 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 T(0.019)QT(0.976)PPVS(0.004)PAPQPT(0.001)EER;T(0.01)QT(0.989)PPVS(0.001)PAPQPTEER;T(0.187)QT(0.812)PPVS(0.001)PAPQPTEER;T(0.153)QT(0.847)PPVSPAPQPTEER;T(0.005)QT(0.995)PPVSPAPQPTEER 164.8 0.00014113 484880000.0 393817.5 616651.0 439929.0 377961.0 434035.0 239545.8 315128.0 230848.6 188092.2 215180.8 True False 460483.02449982276 677868.035975516 450418.5758000244 356785.0705360952 348988.9574963175 226983.59655171994 285276.7945108526 224789.0688543096 190842.6925895173 254191.37566972405 1.8115603776350682 2.6667625295686013 1.7719663958436664 1.4036080870016345 1.3729378370010707 0.8929634058342101 1.1222913985937841 0.8843300377994827 0.7507835074526016 1.0 17.955555557141636 -5.9122360330210535 1.0751794443700617 0.9298338571220036 2.2881191681227797 0.8034926198322313 0.24619086649505756 0.2190846196959114 0.5070755793605789 0.09371042704233509 0.21633175394686777 1.2239508181927129e-06 5.9122360330210535 1.3582853110007762 TQT(ph)PPVSPAPQPTEER ddPTM_PC-9_Lapatinib_30min_R1 3 TQTPPVSPAPQPTEER 16 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 T(0.066)QT(0.934)PPVSPAPQPTEER;T(0.068)QT(0.923)PPVS(0.01)PAPQPTEER;TQT(0.999)PPVS(0.001)PAPQPTEER 210.2 5.490699999999999e-17 457821000.0 317746.0 896426.0 740546.0 826842.0 845280.0 807645.0 826337.0 921980.0 605523.0 799912.0 True False 313214.88377252076 894350.3806732513 679661.1664702268 887650.7189440558 795562.2922844208 773103.906062451 869120.6865620074 964818.5566534693 537322.6233001295 938175.7233842586 0.3338552426433166 0.9532866374404604 0.7244497480903701 0.9461454787404378 0.8479885723482677 0.8240502144669145 0.9263943469213309 1.028398553282857 0.5727313230424026 1.0 19.839498643991362 -4.7558239837705765 24.99999628618634 0.8677425600292359 0.33385439290215924 0.6026875688012833 0.13041126882303336 117.1806214393128 521639.4130633798 0.0301122054080512 0.2575733635089312 1.7545914802522703e-05 4.7558239837705765 -0.5338881671270767 TQTCTSSSLS(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 2 TQTCTSSSLSPTK 13 0 A0A2R8YCF6;A0A2R8YD00;R4GN03;A0A2R8Y500;A0A2U3TZI0;Q9BZR9 A0A2R8YCF6 TRIM8 Probable E3 ubiquitin-protein ligase TRIM8 1 TQTCTSSS(0.002)LS(0.991)PT(0.007)K;TQTCTSSS(0.002)LS(0.823)PT(0.175)K 213.99 2.487e-14 20902400.0 58886.0 52668.0 61585.0 80729.0 68131.0 58588.0 61675.0 74632.0 64493.0 70694.0 True False 77610.52309511066 69691.90102112509 60768.34266107584 62118.17630061671 58672.186676664496 54924.48309823454 67163.9555196935 63099.3392727477 67901.9683149311 68219.02457757878 1.1376668543076551 1.0215904060878407 0.8907829309692048 0.9105696935020792 0.8600560773181739 0.8051197365886452 0.9845340934670583 0.9249522352960505 0.995352377659884 1.0 16.057886506427614 -4.952213067209394 2.5954646205930882 0.9143644698750149 1.1481179170895006 0.5681034013428982 0.05906244418073416 0.24996851353821525 2.848274281525321 0.01607944634531958 0.10952033321028423 1.1163154430512623e-05 4.952213067209394 0.23375344721448577 TQTCTSSSLS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQTCTSSSLSPTK 13 0 A0A2R8YCF6;A0A2R8YD00;R4GN03;A0A2R8Y500;A0A2U3TZI0;Q9BZR9 A0A2R8YCF6 TRIM8 Probable E3 ubiquitin-protein ligase TRIM8 1 TQTCTS(0.011)S(0.005)S(0.068)LS(0.883)PT(0.033)K 163.23 8.2855e-05 6101100.0 22944.0 23162.0 20855.0 28089.0 28241.0 25882.0 26953.0 29872.0 22698.0 21268.0 True False 26827.966035343623 25461.3702876747 21352.26229302794 26515.264395766702 22707.378779714785 24524.702357343012 24399.81671717845 29087.89165200025 23029.915309602795 25123.72004260465 1.0678341419920665 1.013439500380416 0.8498845814560465 1.0553876715232569 0.9038223137818663 0.9761572854559027 0.9711864594813743 1.15778601268734 0.9166602426133075 1.0 14.61676247792164 TQTCTSSSLS(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 2 TQTCTSSSLSPTK 13 0 A0A2R8YCF6;A0A2R8YD00;R4GN03;A0A2R8Y500;A0A2U3TZI0;Q9BZR9 A0A2R8YCF6 TRIM8 Probable E3 ubiquitin-protein ligase TRIM8 1 TQTCTS(0.001)SS(0.003)LS(0.992)PT(0.004)K;TQTCT(0.001)S(0.033)S(0.122)S(0.196)LS(0.546)PT(0.102)K 190.18 1.8327999999999998e-05 21273100.0 46827.0 39474.0 44469.0 42556.0 44951.0 38379.0 35266.0 36086.0 42434.0 35924.0 True False 46159.23839297991 39382.60037827531 40812.930475304056 45685.710202654394 42307.0705570663 36737.619635818686 37091.90092213675 37762.68729841978 37654.63607017028 42133.41553427891 1.0955494067511728 0.9347117929766318 0.9686594347448397 1.084310626692142 1.0041215510441137 0.8719354737792309 0.8803440322078688 0.8962645638755968 0.8937000618792753 1.0 15.36267725188528 -6.719829886394594 7.989436504828429 0.9002593119995991 1.0142636443839863 0.48451157449354487 0.05587244629896891 0.2018814689090656 33.59756617402516 0.018304052730677818 0.018157295733911383 1.9062072351271063e-07 6.719829886394594 0.11400433238438723 TQTCTSSSLSPT(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQTCTSSSLSPTK 13 0 A0A2R8YCF6;A0A2R8YD00;R4GN03;A0A2R8Y500;A0A2U3TZI0;Q9BZR9 A0A2R8YCF6 TRIM8 Probable E3 ubiquitin-protein ligase TRIM8 1 TQTCTSSS(0.003)LS(0.33)PT(0.666)K 165.34 0.00076935 8091000.0 12494.0 13556.0 11441.0 18471.0 14104.0 14132.0 16906.0 14329.0 12906.0 11917.0 True False 14608.987432251724 14901.750091517071 11713.796830234116 17436.129753789974 11340.42244641115 13390.893042035827 15304.541291159398 13952.878932830457 13094.725834246803 14077.457765079904 1.037757503950061 1.0585540614074425 0.8320960379146716 1.238585122737252 0.8055731820088883 0.9512294950905732 1.0871665570983533 0.9911504737340805 0.9301910936454141 1.0 13.78109920209976 TQTES(ph)STPPGIPGGSR ddPTM_PC-9_AZD4547_30min_R2 1 TQTESSTPPGIPGGSR 16 0 E9PER6;Q6A1A2;O15530-4;O15530-5;O15530;H3BQ10;O15530-3 E9PER6 PDPK1;PDPK2P Putative 3-phosphoinositide-dependent protein kinase 2;3-phosphoinositide-dependent protein kinase 1 1 TQT(0.002)ES(0.822)S(0.088)T(0.088)PPGIPGGSR 181.97 1.8140000000000001e-06 12921000.0 15055.0 17872.0 15099.0 29261.0 23406.0 18228.0 15777.0 21178.0 14979.0 18942.0 True False 19842.176836546747 23648.774493991554 14898.777394488665 22515.32852794344 20156.480916968932 17088.200278463493 17181.122435901165 17905.426722026066 15770.759359765423 18278.846345496087 1.085526759265957 1.2937782859484794 0.8150830261867007 1.2317696698342901 1.1027217219283367 0.9348620780257301 0.9399456678585516 0.9795709413815368 0.8627874572429645 1.0 14.157887398295907 -6.758614086030268 21.279301406076716 0.9419383456378007 1.1070707056586842 0.30906090858517676 0.12134895595780336 14.120221582113922 106348.57958533663 0.039744252834985574 0.03797092061005351 1.7433553304280032e-07 6.758614086030268 0.1651323600208835 TQTES(ph)STPPGIPGGSR ddPTM_PC-9_Lapatinib_30min_R1 1 TQTESSTPPGIPGGSR 16 0 E9PER6;Q6A1A2;O15530-4;O15530-5;O15530;H3BQ10;O15530-3 E9PER6 PDPK1;PDPK2P Putative 3-phosphoinositide-dependent protein kinase 2;3-phosphoinositide-dependent protein kinase 1 1 T(0.03)QT(0.045)ES(0.309)S(0.309)T(0.309)PPGIPGGSR 144.08 2.9265e-05 10109000.0 22384.0 20434.0 17505.0 16806.0 17915.0 19507.0 16895.0 16345.0 25949.0 16718.0 True False 22064.80005527715 20386.686328461223 16065.806471254076 18041.969303172533 16861.27492224517 18672.731083037994 17769.740432130104 17104.448370356127 23026.350364916074 19607.684024665257 1.1253139344514624 1.0397294398877517 0.8193627789515724 0.9201479012246856 0.8599319991608763 0.9523170130418692 0.9062641161381868 0.872333945653132 1.1743533981856473 1.0 14.259131520207033 -10.124115658749949 7.329162389626787 1.0000000000026734 0.9523338462983367 0.001045104813455544 0.11073866880461371 0.0 0.0 0.10772998686192327 0.026128359698712505 7.514227528848814e-11 10.124115658749949 -0.04766615370433669 TQTESS(ph)TPPGIPGGSR ddPTM_PC-9_AZD4547_30min_R2 1 TQTESSTPPGIPGGSR 16 0 E9PER6;Q6A1A2;O15530-4;O15530-5;O15530;H3BQ10;O15530-3 E9PER6 PDPK1;PDPK2P Putative 3-phosphoinositide-dependent protein kinase 2;3-phosphoinositide-dependent protein kinase 1 1 TQTES(0.005)S(0.497)T(0.497)PPGIPGGSR 144.41 2.9346e-05 12619000.0 16450.0 15050.0 20453.0 28897.0 21906.0 20309.0 17849.0 22069.0 15732.0 20226.0 True False 21680.7578187442 19914.618181209324 20181.77985624721 22235.243104199504 18864.730025084224 19039.07501949282 19437.526421905295 18658.743145169214 16563.56140248546 19517.89389631526 1.1108144113252538 1.0203261830913508 1.0340142211787144 1.1392234849886773 0.9665351254238375 0.9754676975207434 0.995882369540643 0.9559813801781019 0.8486346677810589 1.0 14.252509764967131 -6.376093117263849 7.372397097467447 0.95684521607532 1.0688807642913938 0.5679478911409321 0.05074525007803289 0.21581415135989537 12.50673594723845 0.01604845869869597 0.018195118178412937 4.2063642987991096e-07 6.376093117263849 0.11203554821607375 TQTESST(ph)PPGIPGGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQTESSTPPGIPGGSR 16 0 E9PER6;Q6A1A2;O15530-4;O15530-5;O15530;H3BQ10;O15530-3 E9PER6 PDPK1;PDPK2P Putative 3-phosphoinositide-dependent protein kinase 2;3-phosphoinositide-dependent protein kinase 1 1 TQT(0.001)ES(0.043)S(0.182)T(0.774)PPGIPGGSR 185.14 1.6886e-07 8222300.0 23868.0 23560.0 19153.0 23812.0 22021.0 22891.0 25698.0 20310.0 20503.0 15434.0 True False 27908.380985511765 25898.88109738436 19609.680158156985 22477.890839545616 17706.14312907118 21690.555662697563 23263.69940259162 19776.8840202238 20802.817587134814 18232.06202452323 1.530730915020654 1.4205129986146818 1.0755601934537506 1.2328770497440984 0.9711541736340816 1.1896929504475384 1.2759774166685331 1.0847310629824913 1.141001909666266 1.0 14.154190117246861 -5.141788975386511 3.8041545737565374 1.1309331279983748 1.5103352958954919 0.7060888792172185 0.09216104796810334 0.12283236398577214 3.0755179996429414 0.02346880406604689 0.07397042069006537 7.214579519833146e-06 5.141788975386511 0.3794021678971171 TQTGDS(ph)SSISSFSYR ddPTM_PC-9_AZD4547_30min_R2 1 TQTGDSSSISSFSYR 15 0 A0A087WXA6;A0A087WT45;Q4V328-4;Q4V328;Q4V328-3;Q4V328-2 A0A087WXA6 GRIPAP1 GRIP1-associated protein 1 1 TQTGDS(0.54)S(0.229)S(0.229)IS(0.002)S(0.001)FSYR 160.03 0.00027638 9714800.0 17744.0 21939.0 24659.0 34879.0 32655.0 29269.0 25149.0 29664.0 31073.0 28239.0 True False 23386.22290187215 29030.352709471834 24332.005548095625 26838.185425178224 28121.41691633 27438.80480306934 27387.21227993143 25080.11041090667 32715.455343213227 27250.36120528263 0.8581986391189047 1.0653199233133153 0.8929057991120769 0.9848744837912643 1.031964923491675 1.0069152697231103 1.0050219912175797 0.9203588246765975 1.2005512549635915 1.0 14.733987732580896 -1.5228787452803378 0.27144808819352806 1.0394915776385436 0.155866142362172 0.20063685678005516 0.08175533157520004 96.21092572453337 1.3455961756149803 0.09064611137339766 39.89932674735077 0.02999999999999998 1.5228787452803378 -0.8836254352763716 TQTGDSS(ph)SISSFSYR ddPTM_PC-9_AZD4547_30min_R2 1 TQTGDSSSISSFSYR 15 0 A0A087WXA6;A0A087WT45;Q4V328-4;Q4V328;Q4V328-3;Q4V328-2 A0A087WXA6 GRIPAP1 GRIP1-associated protein 1 1 TQTGDS(0.035)S(0.277)S(0.277)IS(0.206)S(0.206)FSYR 175.7 2.1837e-28 0.0 19209.0 15979.0 22204.0 38164.0 31245.0 28867.0 19878.0 27994.0 21397.0 27151.0 True False 25317.062427979163 21143.899263624156 21909.560452164136 29365.879427922286 26907.171077958403 27061.941926618678 21647.103491211463 23668.170538124366 22528.001737158727 26200.451754121208 0.9662834315059818 0.8070051410582384 0.8362283466626816 1.1208157669763525 1.0269735549016261 1.0328807373469033 0.8262110781279363 0.9033497116858481 0.8598325688645876 1.0 14.677304066801167 TQTGDSS(ph)SISSFSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQTGDSSSISSFSYR 15 0 A0A087WXA6;A0A087WT45;Q4V328-4;Q4V328;Q4V328-3;Q4V328-2 A0A087WXA6 GRIPAP1 GRIP1-associated protein 1 1 TQTGDS(0.014)S(0.487)S(0.487)IS(0.011)S(0.001)FSYR 199.33 5.846499999999999e-10 5059000.0 11580.0 12121.0 13941.0 16538.0 20521.0 15445.0 17718.0 10522.0 13836.0 9329.6 True False 13540.265284574592 13324.292775101689 14273.406311536919 15611.429476919411 16500.057361231087 14635.037010631433 16039.622772788487 10245.808648980541 14038.325324859647 11020.982626927043 1.228589658738079 1.208993174759851 1.295111950967365 1.4165188355144256 1.4971493849302766 1.327924878029872 1.4553713870848175 0.9296638054711603 1.2737816399928328 1.0 13.427965239374588 -7.75644156759262 24.999941473850207 1.0762920343893858 1.3474875437690368 0.5360608855084283 0.11898269345850696 99.24192562218722 496433.0674932393 0.05958393240846618 0.03301860903065334 1.7520981554309623e-08 7.75644156759262 0.271195509379651 TQTGDSS(ph)SISSFSYR ddPTM_PC-9_Lapatinib_30min_R1 1 TQTGDSSSISSFSYR 15 0 A0A087WXA6;A0A087WT45;Q4V328-4;Q4V328;Q4V328-3;Q4V328-2 A0A087WXA6 GRIPAP1 GRIP1-associated protein 1 1 TQT(0.002)GDS(0.087)S(0.295)S(0.295)IS(0.163)S(0.159)FSYR 110.32 0.00053921 8055500.0 26949.0 29609.0 27044.0 29155.0 20437.0 28417.0 22606.0 24474.0 27321.0 22020.0 True False 26564.702318158674 29540.442179671554 24820.54671285892 31299.15595822889 19234.935840687944 27201.67115326243 23776.428067992503 25611.151386729638 24243.821277115563 25826.12766019433 1.028597963569378 1.1438200325015073 0.9610634253587577 1.2119182701350195 0.7447859041731079 1.0532617011410588 0.9206346526598714 0.9916760159984792 0.9387323409882479 1.0 14.656543723189724 -6.2414870607871284 24.999417712859287 0.945642181215882 1.0815058742191102 0.343445567756007 0.09791237372662498 973.0690374114193 1219214.5452197858 0.026893744068419934 0.03467042222362012 5.734729521373671e-07 6.2414870607871284 0.1358636930032282 TQTGDSSSIS(ph)SFSYR ddPTM_PC-9_Lapatinib_30min_R1 1 TQTGDSSSISSFSYR 15 0 A0A087WXA6;A0A087WT45;Q4V328-4;Q4V328;Q4V328-3;Q4V328-2 A0A087WXA6 GRIPAP1 GRIP1-associated protein 1 1 TQTGDS(0.212)S(0.048)S(0.048)IS(0.683)S(0.01)FSYR 147.49 0.00012291 6818400.0 30142.0 29477.0 27930.0 29704.0 28658.0 24508.0 21240.0 25821.0 23718.0 14202.0 True False 29712.169552634165 29408.747817561467 25633.70321291782 31888.5312496392 26972.3927837958 23459.84997093839 22339.703271881834 27020.737924194877 21046.629078387585 16656.796777024512 1.7837865197237401 1.7655704281705777 1.5389335390268775 1.9144455969844407 1.6193025072503775 1.4084250582499538 1.3411764321154482 1.6222049344725047 1.2635460082828271 1.0 14.023823366193763 -8.26832577947361 0.2043064937273972 0.7984652999300541 1.9540389531036835 0.7371619517824693 0.13431822483140787 1.68516431313152 0.3249108545704129 0.7850849164274195 0.6145986184858518 5.391060684901659e-09 8.26832577947361 1.1555736531736294 TQTPPLGQT(ph)PQLGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQTPPLGQTPQLGLK 15 0 H0Y3P2;D3DQV9;P78344-2;P78344;E9PKF8 H0Y3P2 EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 1 T(0.016)QT(0.446)PPLGQT(0.539)PQLGLK 102.53 0.0035736999999999995 156450000.0 277410.0 344680.0 336880.0 426910.0 474910.0 314060.0 379040.0 298440.0 254150.0 257410.0 True False 324370.0339027492 378897.5524892369 344912.49682451517 402991.61676089355 381854.79466996086 297590.14072896796 343134.58718804276 290606.26622331847 257866.46294543773 304076.39534356055 1.0667386185509726 1.2460603923600835 1.1342955326565747 1.3252972704624892 1.2557857187123072 0.9786689966274295 1.1284486150276556 0.9557014969707764 0.8480318330993349 1.0 18.21407430250389 -7.318277959605504 1.1990217855533836 0.9273385513581082 1.203509282023691 0.5571082502766579 0.09600600305399731 0.3557165707497528 0.9864681085148992 0.06612751416266831 0.03600731226870771 4.8053169739881755e-08 7.318277959605504 0.27617073066558284 TQTPPVS(ph)PAPQPT(ph)EERLPSSPVYEDAASFK ddPTM_PC-9_Lapatinib_30min_R1 1 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 T(0.083)QT(0.197)PPVS(0.535)PAPQPT(0.416)EERLPS(0.358)S(0.358)PVY(0.055)EDAASFK 50.088 0.044241 13079000.0 32541.0 24179.0 24914.0 26884.0 28229.0 30461.0 23161.0 19947.0 29852.0 31909.0 True False 32076.959372711466 24123.015011053336 22865.667090821138 28861.139042394978 26568.62572034937 29158.25403805915 24360.163252356644 20873.81044010363 26489.753404503994 37424.428133930094 0.8571128797992118 0.6445793887544455 0.6109824045672043 0.7711845038516063 0.7099273668329341 0.7791235696030159 0.6509161119357493 0.5577589686982769 0.707819857920223 1.0 15.191692650819206 -11.719000995568997 2.1002651141819286 1.7902671634742606 0.6939025571375975 0.5376548086112958 0.08367475848769887 5547676.499721775 1094230.3833746535 20811834.44935985 0.022362559444794775 1.909848880457389e-12 11.719000995568997 -1.096364606336663 TQTPPVS(ph)PAPQPTEER ddPTM_PC-9_AZD4547_30min_R2 2 TQTPPVSPAPQPTEER 16 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 T(0.013)QT(0.265)PPVS(0.722)PAPQPTEER;T(0.008)QT(0.315)PPVS(0.675)PAPQPT(0.001)EER 94.61 0.0025764 65152000.0 58265.0 73496.0 74235.0 58046.0 56038.0 68795.0 71495.0 90913.0 82433.0 71992.0 True False 76792.05801271313 97252.1447073861 73250.59539571272 44664.39150176021 48258.09098629003 64493.23777468162 77857.9164958328 76864.48482290846 86790.24008969517 69471.58199265947 1.1053736766902351 1.3998838362089119 1.0543965358879053 0.6429159984650926 0.6946450563251761 0.9283398466655923 1.1207160433464645 1.1064162153530654 1.2492912583862799 1.0 16.084135330010994 -10.022031558371705 15.703283009580185 0.9999999739735282 1.0250955563385085 0.000771656764247286 0.21872581773594107 0.0 0.0 0.2399230766889144 0.058189893365385915 9.505357196737007e-11 10.022031558371705 0.025095582364980218 TQTPPVS(ph)PAPQPTEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TQTPPVSPAPQPTEER 16 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 T(0.001)QTPPVS(0.943)PAPQPT(0.055)EER;T(0.018)QT(0.072)PPVS(0.91)PAPQPTEER;TQTPPVS(0.912)PAPQPT(0.088)EER 138.98 1.4285999999999998e-05 384757000.0 529424.0 909193.0 687908.0 522981.0 635689.0 321875.0 489122.0 270665.0 289407.0 361372.0 True False 619045.0265993616 999451.6723927902 704310.3356256188 493680.0700972781 511130.30378166976 304995.30837144627 442788.82322338043 263560.3305432723 293639.0298707478 426885.88298082305 1.4501417153379392 2.341261944325501 1.649879660361733 1.1564684843875608 1.197346466958785 0.7144656699391194 1.0372533758472209 0.6174023106665071 0.6878630603109893 1.0 18.703490928213945 -5.934951512214241 1.3490405338960514 0.816927927447792 1.9338809603628881 0.7278367940366498 0.2593337110946704 0.21005887948397228 0.7757946588281986 0.08933041070438535 0.17581064480435749 1.1615782936262703e-06 5.934951512214241 1.116953032915096 TQTPPVS(ph)PAPQPTEER ddPTM_PC-9_Lapatinib_30min_R1 2 TQTPPVSPAPQPTEER 16 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 T(0.05)QT(0.213)PPVS(0.732)PAPQPT(0.006)EER;TQTPPVS(0.591)PAPQPT(0.409)EER 184.22 7.707399999999999e-08 32121000.0 16151.6 33203.0 38117.0 30178.0 51945.0 55241.0 73706.0 67067.0 66740.0 81316.0 True False 15921.275222159322 33126.120493486254 34983.167395874996 32397.39079085686 48889.697227799355 52878.47120306049 77522.1360337723 70183.1776601209 59223.038396643366 95371.36225324085 0.1669397903731662 0.3473382335205198 0.3668099791107495 0.33969726367996755 0.5126245035483701 0.5544481063681526 0.8128450113559953 0.7358936267866508 0.6209729734109034 1.0 16.54126850387619 -6.491181333506556 0.27305353963726536 1.0021718316050197 4.561956978527057e-14 0.8826433074322573 0.08236103635426965 1.1483654012002247 0.1588318807547992 0.1343196342088957 0.38370633140739296 3.227146391125409e-07 6.491181333506556 -1.0021718316049741 down TQTPPVS(ph)PAPQPTEERLPS(ph)SPVYEDAASFK ddPTM_PC-9_AZD4547_30min_R2 2 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 T(0.007)QT(0.039)PPVS(0.928)PAPQPT(0.083)EERLPS(0.441)S(0.441)PVY(0.057)EDAAS(0.003)FK;T(0.175)QT(0.358)PPVS(0.467)PAPQPT(0.009)EERLPS(0.391)S(0.391)PVY(0.184)EDAAS(0.026)FK 68.38600000000001 0.00034514 98288800.0 85582.0 82468.5 104026.0 136371.0 121791.0 96219.0 98080.0 119922.0 98242.0 111430.0 True False 112795.29578381537 109124.8298655854 102646.54727061896 104932.77286094715 104882.42191568654 90202.41071941378 106808.92999386355 101390.81043341276 103434.87155498205 107528.86961665255 1.0489768578981438 1.0148421559216847 0.9545952415994013 0.9758567465187661 0.9753884913846788 0.8388669111931639 0.993304685287257 0.942917104912175 0.9619265219074108 1.0 16.714364524587566 -4.932467664048056 1.1986723778109647 0.9486804745340213 1.0830237982453332 0.345405546506661 0.042798211861467886 1.2936582407798582 1.9101966150645722 0.013175471083113972 0.2035274979134201 1.1682407094816364e-05 4.932467664048056 0.13434332371131197 TQTPPVS(ph)PAPQPTEERLPS(ph)SPVYEDAASFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 T(0.11)QT(0.262)PPVS(0.504)PAPQPT(0.132)EERLPS(0.446)S(0.446)PVY(0.098)EDAAS(0.001)FK;T(0.003)QT(0.008)PPVS(0.959)PAPQPT(0.113)EERLPS(0.386)S(0.386)PVY(0.145)EDAAS(0.001)FK;T(0.007)QT(0.007)PPVS(0.786)PAPQPT(0.241)EERLPS(0.429)S(0.429)PVY(0.101)EDAASFK 69.952 0.00025152 85604900.0 112636.9 89782.0 96955.8 142030.0 134088.0 142192.0 139043.0 132666.0 114242.6 108072.2 True False 131704.10248981876 98694.96361143321 99267.59397891894 134072.51956747274 107814.41895876173 134735.20120529 125871.84045585434 129183.65807124593 115913.1818992349 127664.83436093573 1.0316396300445836 0.7730786955192491 0.7775641152540744 1.0501914661042924 0.8445114858642072 1.0553822583936063 0.985955459746948 1.0118969622129157 0.9079491817732955 1.0 16.962001659776895 -5.761981649861679 24.99999979271618 0.9777252733202042 0.8519926061052256 0.26897689956792714 0.0892570866450836 17.820944986311748 821668.713592375 0.02404596598530088 0.038251243408085854 1.7298894502659794e-06 5.761981649861679 -0.12573266721497856 TQTPPVS(ph)PAPQPTEERLPSSPVYEDAASFK ddPTM_PC-9_AZD4547_30min_R2 1 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 T(0.223)QT(0.34)PPVS(0.431)PAPQPT(0.002)EERLPS(0.002)S(0.002)PVY(0.001)EDAASFK 47.795 0.0074268 4857000.0 42119.0 36581.0 46080.0 80508.0 73308.0 59006.0 46598.0 49799.0 43311.0 52558.0 True False 55511.96587037608 48405.09286955604 45468.949091862836 61948.12443620081 63130.44958818928 55316.34549215583 50745.13172771265 42103.708817177074 45600.33103884106 50717.96041741015 1.0945228359640478 0.9543974653393168 0.8965058673032628 1.2214238097582417 1.2447355743137938 1.090665812207369 1.0005357334971454 0.8301538246148394 0.899096309542993 1.0 15.630209109355395 -7.52844810168999 4.3308022554703784 0.8988443883837783 1.0812776083168039 0.35005438688443413 0.10588924335640872 0.24645638757033994 11.385012320629727 0.056557770509216704 0.03336080024329357 2.96177387704041e-08 7.52844810168999 0.18243321993302553 TQTPPVS(ph)PAPQPTEERLPSSPVYEDAASFK ddPTM_PC-9_Lapatinib_30min_R1 1 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 TQT(0.002)PPVS(0.63)PAPQPT(0.326)EERLPS(0.019)S(0.019)PVY(0.005)EDAASFK 64.779 8.2205e-05 12056000.0 50137.0 31677.0 42222.0 37117.0 35242.0 32351.0 22388.0 23913.0 33630.0 23140.0 True False 49422.037186000285 31603.653852729087 38750.67014163324 39846.707998682294 33169.13484843783 30967.423143864344 23547.141094674687 25024.085278698436 29842.235260400295 27139.718167888153 1.82102249110592 1.1644798098943667 1.4278213908456583 1.4682064033306401 1.222162096277172 1.1410370200713855 0.8676265887880803 0.9220466153663694 1.0995779350321246 1.0 14.728118118732846 -6.653213533407907 1.6132943268758435 0.9683331982068114 1.4512441383017682 0.6492189676548424 0.16228084887046004 0.23779984096314524 1.2786985999462692 0.0655964986831674 0.0650100897848422 2.2222170049155888e-07 6.653213533407907 0.48291094009495683 TQTPPVSPAPQPT(ph)EERLPS(ph)SPVYEDAASFK ddPTM_PC-9_Lapatinib_30min_R1 1 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 T(0.008)QT(0.046)PPVS(0.23)PAPQPT(0.579)EERLPS(0.445)S(0.443)PVY(0.236)EDAAS(0.013)FK 56.335 0.006780500000000001 9909400.0 19746.0 17006.0 18835.0 20827.0 21909.0 23302.0 15587.0 19304.0 21944.0 18646.0 True False 19464.41841902709 16966.623651845526 17286.459005202552 22358.6870568353 20620.355694751284 22305.42777961506 16394.018592223263 20200.9343127167 19472.43563943573 21868.93625576675 0.8900487061365138 0.7758321416923741 0.7904572404907982 1.022394815885908 0.9429062051115441 1.019959430982072 0.7496486523390102 0.9237273398421378 0.8904153092631989 1.0 14.41659542637104 -5.736634678663611 24.999768300060065 0.9284748982134914 0.8144845851931984 0.30700295460963156 0.07984088098445842 297.9504759787227 300291.27830533695 0.022042395985929678 0.03815791351735767 1.8338563834080558e-06 5.736634678663611 -0.11399031302029294 TQTPPVSPAPQPT(ph)EERLPSSPVYEDAASFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 T(0.001)QT(0.001)PPVS(0.006)PAPQPT(0.279)EERLPS(0.229)S(0.229)PVY(0.252)EDAAS(0.004)FK;TQT(0.001)PPVS(0.008)PAPQPT(0.356)EERLPS(0.29)S(0.29)PVY(0.054)EDAAS(0.001)FK;T(0.004)QT(0.024)PPVS(0.206)PAPQPT(0.742)EERLPS(0.007)S(0.007)PVY(0.009)EDAAS(0.001)FK;T(0.005)QT(0.012)PPVS(0.223)PAPQPT(0.668)EERLPS(0.04)S(0.04)PVY(0.012)EDAAS(0.001)FK 56.36600000000001 0.0013338 178396600.0 300740.2 111129.5 192773.2 373205.0 346954.8 325531.0 269559.6 236528.0 279750.9 246413.3 True False 351649.57597029535 122161.70233072048 197369.6441844324 352295.53379693435 278971.4975758712 308459.58129542606 244024.96324549871 230319.39062213208 283841.7276757941 291086.08068338985 1.2080604305939986 0.4196755201894865 0.6780456273314852 1.2102795604992227 0.9583814413967271 1.0596850958013795 0.8383257717874911 0.7912415120688893 0.9751126780415332 1.0 18.1510863279505 -5.720805630231119 24.999798161481458 0.9644468529073826 0.7337017693203148 0.16216926348628613 0.21060668737437602 247.49261979018297 152267.29539961106 0.05615412094938987 0.09726037908731272 1.9019293035069584e-06 5.720805630231119 -0.2307450835870678 TQTPPVSPAPQPT(ph)EERLPSSPVYEDAASFK ddPTM_PC-9_Lapatinib_30min_R1 3 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 TQTPPVS(0.007)PAPQPT(0.552)EERLPS(0.19)S(0.19)PVY(0.06)EDAAS(0.002)FK;TQTPPVS(0.023)PAPQPT(0.864)EERLPS(0.047)S(0.047)PVY(0.018)EDAASFK;TQTPPVS(0.003)PAPQPT(0.461)EERLPS(0.25)S(0.25)PVY(0.036)EDAASFK 65.059 0.00012183 409277000.0 388310.0 288895.0 348908.0 304143.8 249001.0 269742.3 191441.9 216866.2 230933.9 198357.8 True False 382772.6281926679 288226.08137715544 320222.1310638281 326511.5496459745 234355.25073480132 258206.05062901299 201353.82484958906 226942.59536098712 204923.69234022486 232643.681434845 1.645317103958693 1.2389164390775729 1.3764488641549917 1.4034834199329778 1.00735704184786 1.1098777711756898 0.8655030887051232 0.9754943438020923 0.8808478746396408 1.0 17.82776247869765 -6.34337022817021 1.1974179043521722 0.9329881189576092 1.4373259502984428 0.7788825675947441 0.1149008347059016 0.21181206566294086 0.6276145027443127 0.046936747098738046 0.06324366446032256 4.535548045524827e-07 6.34337022817021 0.5043378313408335 TQTPPVSPAPQPTEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQTPPVSPAPQPTEER 16 0 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 0 138.31 1.3141e-06 0.0 6756.1 5392.7 5599.9 7146.0 7573.7 5941.7 8149.0 6918.0 6627.1 6479.8 False True 7899.774290942518 5928.051616887288 5733.422853739014 6745.632787644583 6089.6878532603605 5630.106792234946 7377.067726349096 6736.4098302268885 6724.008800258562 7654.536445931428 1.0320382359850726 0.774449459971961 0.7490228695411683 0.8812594773430141 0.7955658577466409 0.7355255059537256 0.9637510747329692 0.8800545764998551 0.8784344875426827 1.0 12.902099296298898 -8.553176203080762 0.7045830352408504 0.995854417735746 0.8306091771810673 0.21084655254930507 0.08866717436667795 1.202083623015448 1.3516623378801647 0.08801976589255861 0.034479392708925624 2.7978459400322616e-09 8.553176203080762 -0.1652452405546787 TQTPPVSPAPQPTEERLPS(ph)S(ph)PVYEDAASFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 2 T(0.058)QT(0.096)PPVS(0.208)PAPQPT(0.268)EERLPS(0.609)S(0.606)PVY(0.145)EDAAS(0.009)FK 50.088 0.039004000000000004 71250000.0 12105.0 9351.2 8185.5 10660.0 13757.0 13629.0 12356.0 13469.0 12263.0 11315.0 True False 14154.137415351934 10279.525336072184 8380.673363681624 10062.754760186299 11061.414605450815 12914.271247516719 11185.550230306715 13115.45302158514 12442.323175683287 13366.319930509278 1.0589404928909731 0.7690617454553564 0.6269993092528279 0.7528440746968482 0.8275587194499658 0.9661800192317157 0.8368459148411636 0.9812314152116378 0.9308712675119406 1.0 13.706314690993052 -6.630297101319155 4.561092847065481 0.9348290637655238 0.7873685700355372 0.2770951705706167 0.10872923839475118 0.29609983082419244 10.563959191500198 0.038120966876456025 0.03801437243992284 2.3426256743000922e-07 6.630297101319155 -0.1474604937299866 TQTPPVSPAPQPTEERLPS(ph)SPVYEDAASFK ddPTM_PC-9_AZD4547_30min_R2 6 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 TQTPPVS(0.001)PAPQPT(0.151)EERLPS(0.408)S(0.408)PVY(0.031)EDAASFK;TQTPPVS(0.047)PAPQPT(0.034)EERLPS(0.388)S(0.388)PVY(0.141)EDAAS(0.002)FK;TQTPPVSPAPQPT(0.003)EERLPS(0.466)S(0.466)PVY(0.064)EDAASFK;TQTPPVSPAPQPT(0.005)EERLPS(0.491)S(0.491)PVY(0.013)EDAASFK;TQTPPVS(0.002)PAPQPT(0.007)EERLPS(0.444)S(0.444)PVY(0.095)EDAAS(0.007)FK;TQTPPVS(0.002)PAPQPT(0.157)EERLPS(0.37)S(0.37)PVY(0.102)EDAASFK 80.685 4.3064999999999996e-07 1350917400.0 297325.6 234880.1 341674.0 526389.0 454868.0 354018.0 285728.3 378359.0 307003.8 368779.0 True False 391868.95604333276 310800.4989943036 337143.17951417435 405038.1486789792 391717.42979320866 331881.19849578076 311157.5651709388 319892.31037487276 323231.3941073203 355868.15945759165 1.1011632977803154 0.8733585479184779 0.9473822553499656 1.1381691166086103 1.1007375045585923 0.9325959338470421 0.8743619143820003 0.8989068054372926 0.908289728982734 1.0 18.440983331005803 -6.9220287164066745 8.147720763680155 0.9107729981309728 1.024286107512924 0.31801070539051046 0.07928545383304712 0.3357211402291899 30.88448918087415 0.029933113407706644 0.02639149117945316 1.1966614030819007e-07 6.9220287164066745 0.11351310938195114 TQTPPVSPAPQPTEERLPS(ph)SPVYEDAASFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 TQTPPVS(0.002)PAPQPT(0.012)EERLPS(0.446)S(0.446)PVY(0.092)EDAAS(0.002)FK;TQTPPVS(0.002)PAPQPT(0.008)EERLPS(0.463)S(0.463)PVY(0.065)EDAASFK;TQTPPVS(0.013)PAPQPT(0.161)EERLPS(0.387)S(0.387)PVY(0.046)EDAAS(0.004)FK;TQTPPVS(0.005)PAPQPT(0.017)EERLPS(0.467)S(0.467)PVY(0.043)EDAAS(0.002)FK;TQTPPVS(0.001)PAPQPT(0.005)EERLPS(0.472)S(0.472)PVY(0.051)EDAASFK;TQTPPVS(0.001)PAPQPT(0.018)EERLPS(0.468)S(0.468)PVY(0.046)EDAASFK;TQTPPVSPAPQPT(0.003)EERLPS(0.476)S(0.476)PVY(0.044)EDAASFK 76.10600000000001 1.0286e-06 2070621800.0 375183.0 296431.0 359372.0 471720.0 515105.0 476749.0 472577.0 484668.0 465287.0 385441.0 True False 438694.0716979754 325858.7106357707 367940.79140589974 445291.05773687456 414173.8729621811 451747.4431713511 427811.08539880614 471945.978548193 472090.94213847636 455318.4021507224 0.96348856014995 0.715672173794335 0.8080955868858154 0.97797729156897 0.9096356988995112 0.9921572267615285 0.9395866351502951 1.0365185688057617 1.0368369473066055 1.0 18.796516242941927 -5.764317499992698 24.328216902054447 0.9815014959073716 0.8177440805544607 0.5269200902128455 0.06725460660881323 38.45615423643209 325069.4604746679 0.01856804159359293 0.028979852452254356 1.7206102272617777e-06 5.764317499992698 -0.16375741535291088 TQTPPVSPAPQPTEERLPS(ph)SPVYEDAASFK ddPTM_PC-9_Lapatinib_30min_R1 7 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 TQTPPVS(0.003)PAPQPT(0.017)EERLPS(0.454)S(0.454)PVY(0.071)EDAASFK;TQTPPVS(0.023)PAPQPT(0.124)EERLPS(0.372)S(0.372)PVY(0.102)EDAAS(0.007)FK;TQTPPVS(0.005)PAPQPT(0.089)EERLPS(0.422)S(0.422)PVY(0.057)EDAAS(0.006)FK;TQTPPVSPAPQPT(0.266)EERLPS(0.35)S(0.35)PVY(0.034)EDAASFK;TQTPPVS(0.004)PAPQPT(0.036)EERLPS(0.444)S(0.444)PVY(0.072)EDAAS(0.001)FK;TQTPPVSPAPQPT(0.079)EERLPS(0.406)S(0.406)PVY(0.109)EDAAS(0.001)FK;T(0.001)QT(0.002)PPVS(0.021)PAPQPT(0.186)EERLPS(0.529)S(0.186)PVY(0.072)EDAAS(0.004)FK 70.983 2.4859e-05 1333500300.0 218022.0 155660.0 207742.0 179655.0 185683.0 190701.0 136581.5 141391.4 202620.0 151111.8 True False 214912.9662996619 155299.57883372204 190662.2546673102 192867.42801151166 174761.49100682358 182545.1627757436 143653.02177158778 147960.96061868267 179798.80191680952 177231.2732861836 1.2126131145750554 0.876253812062573 1.0757822314995107 1.0882245804332717 0.9860646361470757 1.0299827981316787 0.8105399183112821 0.8348467958008924 1.0144868824955064 1.0 17.43527367107258 -7.155852909215072 8.020637064124376 0.9014365996916541 1.0385583084713057 0.2865251275208659 0.09923062212487893 0.3629518793032726 24.70882841108267 0.036625393473072206 0.02835155776932625 6.984689277976095e-08 7.155852909215072 0.13712170877965157 TQTPPVSPAPQPTEERLPSS(ph)PVYEDAASFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247-3;Q14247;Q14247-2;H0YEV2;H0YCD9 Q14247-3 CTTN Src substrate cortactin 1 TQTPPVSPAPQPT(0.001)EERLPS(0.385)S(0.6)PVY(0.013)EDAASFK 110.12 1.1792e-15 138370000.0 26890.0 19928.0 26448.0 40710.0 42911.0 39092.0 33935.0 30458.0 38575.0 19999.0 True False 31441.94589829106 21906.32014043613 27078.62062459856 38429.15068360077 34502.89758919093 37041.946702467045 30720.431131875896 29658.509772918573 39139.08639826981 23624.660388003118 1.3308951486243439 0.9272649756929594 1.1462014767564406 1.6266541000993837 1.4604611038858324 1.567935627183762 1.3003544020245934 1.2554047036366929 1.656704721061095 1.0 14.528005969832774 -5.637590298102676 7.910719272778812 1.4239331073346497 1.1068142922747133 0.2695364243863466 0.20576394777082965 0.2650167847727754 17.203965183749983 0.05323580042111423 0.09245299936572238 2.3036139609981573e-06 5.637590298102676 -0.31711881505993644 TQVLS(ph)PDSLFTAK ddPTM_PC-9_AZD4547_30min_R2 2 TQVLSPDSLFTAK 13 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-1;H0Y8L4;H0Y948 A8MQ02 MLLT4 Afadin 1 T(0.001)QVLS(0.806)PDS(0.193)LFTAK;T(0.281)QVLS(0.705)PDS(0.014)LFTAK 151.38 9.163799999999999e-05 28507000.0 47992.0 45340.0 57779.0 77038.0 57067.0 53630.0 39142.0 62515.0 47536.0 44731.0 True False 63252.457704387314 59995.26832797545 57012.812707872064 59278.079325235136 49144.23209812296 50276.507622009914 42625.562171898535 52854.74320178767 50048.655913332615 43164.981305056746 1.4653651129226213 1.3899060422145264 1.3208117085687943 1.37329097645852 1.1385208706754553 1.1647522158458588 0.9875033159554498 1.2244820130524596 1.159473591790238 1.0 15.397573743203456 -6.255387585006098 2.024048025243677 1.111346412312248 1.3964616318300407 0.7590707720355033 0.075804162888604 0.16895545389193942 1.3593505175857272 0.025942432925388222 0.03386314229214914 5.554083632420915e-07 6.255387585006098 0.2851152195177926 TQVLS(ph)PDSLFTAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TQVLSPDSLFTAK 13 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-1;H0Y8L4;H0Y948 A8MQ02 MLLT4 Afadin 1 T(0.012)QVLS(0.984)PDS(0.003)LFTAK;T(0.014)QVLS(0.977)PDS(0.009)LFTAK;T(0.406)QVLS(0.447)PDS(0.147)LFTAK 191.63 9.8813e-06 19264800.0 85133.6 76265.0 76105.0 69093.3 100901.0 85666.0 95394.0 90474.0 95196.0 69431.7 True False 99545.03701475487 83836.0851821741 77919.63182981957 65222.22640450096 81130.17337388902 81173.52415362584 86357.5897272482 88099.15336512684 96588.06140686161 82019.11758896524 1.213680906854179 1.022152976606192 0.9500179241175205 0.7952076091742285 0.9891617437347824 0.9896902885547118 1.0528958645961664 1.074129495109072 1.1776286339839441 1.0 16.323672601916456 -7.442534611923131 2.2378126630684325 1.094540492187143 0.9825349107496284 0.13193082431825975 0.10360670850609714 0.6031759850405716 5.928277368235126 0.05960798643903409 0.03364010927502046 3.609652446296636e-08 7.442534611923131 -0.11200558143751471 TQVLSPDS(ph)LFTAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TQVLSPDSLFTAK 13 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-1;H0Y8L4;H0Y948 A8MQ02 MLLT4 Afadin 1 T(0.109)QVLS(0.375)PDS(0.496)LFT(0.02)AK 84.75299999999999 0.037643 0.0 5969.5 6016.6 6668.2 7565.0 9001.4 6367.3 7745.0 8802.9 7938.1 7035.3 True False 6980.018447000695 6613.888285675833 6827.195177289329 7141.157576060914 7237.640287090561 6033.387579008964 7011.337531055806 8571.833202443524 8054.179695090227 8310.744198595841 0.8398788700751996 0.7958238308902945 0.8214902316982433 0.8592681239385833 0.8708775188043222 0.7259744055205486 0.8436473754348522 1.0314158392568256 0.96912857653001 1.0 13.02076195582754 -7.705788525350399 6.034627812225788 1.0000479413484191 0.8197468968784378 0.8042386025944344 0.04025248828805693 0.0801689003666504 6.0523881918387685 0.01983597383206678 0.011100150317909938 1.9688447623999816e-08 7.705788525350399 -0.1803010444699813 TRDDGDEEGLLTHS(ph)EEELEHSQDTDADDGALQ ddPTM_PC-9_AZD4547_30min_R2 3 TRDDGDEEGLLTHSEEELEHSQDTDADDGALQ 32 1 Q9UKM9-2;Q9UKM9 Q9UKM9-2 RALY RNA-binding protein Raly 1 TRDDGDEEGLLT(0.002)HS(0.542)EEELEHS(0.099)QDT(0.357)DADDGALQ;TRDDGDEEGLLT(0.002)HS(0.437)EEELEHS(0.28)QDT(0.28)DADDGALQ;TRDDGDEEGLLT(0.114)HS(0.472)EEELEHS(0.135)QDT(0.279)DADDGALQ 80.355 1.293e-07 116111000.0 68075.8 75584.4 89809.0 128982.0 111832.0 96884.0 83830.0 105218.0 81475.0 88983.0 True False 89722.48833539631 100015.57916649806 88618.07397984176 99247.19265203529 96306.05716083353 90825.82816428882 91290.7075997713 88958.97576910653 85781.60216549091 85867.73225431738 1.0448917885668876 1.1647632532122605 1.032029979752797 1.1558147635492633 1.12156283428565 1.0577410836388095 1.0631549850343376 1.0360000600182815 0.9989969446430543 1.0 16.389828470605458 -7.62147180619189 1.0771429841100277 0.9984960477226877 1.1042221640064873 0.4826416120235414 0.04088309869140849 0.4344874859792319 0.9223962722519881 0.03236109915023863 0.01402025581096748 2.390717132417272e-08 7.62147180619189 0.10572611628379958 TRDDGDEEGLLTHS(ph)EEELEHSQDTDADDGALQ ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TRDDGDEEGLLTHSEEELEHSQDTDADDGALQ 32 1 Q9UKM9-2;Q9UKM9 Q9UKM9-2 RALY RNA-binding protein Raly 1 TRDDGDEEGLLTHS(0.333)EEELEHS(0.333)QDT(0.333)DADDGALQ;TRDDGDEEGLLT(0.033)HS(0.425)EEELEHS(0.425)QDT(0.116)DADDGALQ 75.695 3.3093e-07 24190000.0 23474.4 28439.4 30977.9 36068.6 40148.5 32140.1 33163.3 28390.6 27141.3 27229.6 True False 27448.152279466125 31262.67568255317 31716.53062033998 34047.79327797895 32281.68963341877 30454.616576587574 30021.832142500058 27645.3768323272 27538.19016620506 32166.110930605 0.8533251762602767 0.9719134448674602 0.98602316856909 1.05849890748165 1.0035931823733095 0.946792002374493 0.9333373315558416 0.8594566154413008 0.8561243299078277 1.0 14.973253895885088 -7.298985682600473 2.3809381673568075 0.8949949029898704 0.97857345804905 0.1749759428226988 0.06124929389577517 0.43871401412952704 4.879345041971339 0.03066134225561109 0.019624661827796094 5.023591505389506e-08 7.298985682600473 0.08357855505917966 TRDDGDEEGLLTHS(ph)EEELEHSQDTDADDGALQ ddPTM_PC-9_Lapatinib_30min_R1 4 TRDDGDEEGLLTHSEEELEHSQDTDADDGALQ 32 1 Q9UKM9-2;Q9UKM9 Q9UKM9-2 RALY RNA-binding protein Raly 1 TRDDGDEEGLLT(0.002)HS(0.333)EEELEHS(0.333)QDT(0.333)DADDGALQ;TRDDGDEEGLLT(0.013)HS(0.698)EEELEHS(0.144)QDT(0.144)DADDGALQ;TRDDGDEEGLLT(0.008)HS(0.702)EEELEHS(0.162)QDT(0.128)DADDGALQ;TRDDGDEEGLLT(0.01)HS(0.947)EEELEHS(0.036)QDT(0.007)DADDGALQ 91.76700000000001 3.5733999999999993e-10 207393000.0 75072.0 65677.0 70281.0 56162.8 67740.0 65627.5 56024.4 56315.8 68992.0 56705.8 True False 74001.45951348142 65524.92894168289 64502.76747250544 60293.199665608554 63755.6663819641 62820.76481017464 58925.06930250545 58932.43765893553 61221.39444203195 66507.321974271 1.1126813908115198 0.9852287988235616 0.9698596418821217 0.9065648394162308 0.9586262758652137 0.9445691533704733 0.8859937154784427 0.8861045056322386 0.920521118948618 1.0 16.021225559177914 -1.5228789432749714 0.7900229125311805 0.9220245858564239 45.53514587845403 0.7194899185519228 0.03397397555041354 235.36985967801192 0.8554106681820809 0.012105274874301407 18774.137900994687 0.029999986323018344 1.5228789432749714 44.613121292597604 TRDDGDEEGLLTHSEEELEHS(ph)QDTDADDGALQ ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TRDDGDEEGLLTHSEEELEHSQDTDADDGALQ 32 1 Q9UKM9-2;Q9UKM9 Q9UKM9-2 RALY RNA-binding protein Raly 1 TRDDGDEEGLLT(0.014)HS(0.374)EEELEHS(0.48)QDT(0.131)DADDGALQ 58.711999999999996 0.00044130000000000005 13918000.0 9185.3 14148.0 12477.0 12355.0 15767.0 10825.0 12083.0 13183.0 12289.0 12004.0 True False 10740.189872055524 15552.519939125368 12774.498999285994 11662.789405450438 12677.569534356533 10257.31794367661 10938.410766655565 12836.960218543092 12468.703376496125 14180.230176388288 0.7574058910509911 1.0967748580712111 0.9008668294085241 0.8224682716977558 0.8940312940382408 0.7233534164174727 0.7713845706728566 0.9052716393784711 0.879301902818048 1.0 13.791593330437086 TRDDGDEEGLLTHSEEELEHSQDT(ph)DADDGALQ ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TRDDGDEEGLLTHSEEELEHSQDTDADDGALQ 32 1 Q9UKM9-2;Q9UKM9 Q9UKM9-2 RALY RNA-binding protein Raly 1 TRDDGDEEGLLTHS(0.034)EEELEHS(0.363)QDT(0.602)DADDGALQ 82.6 8.419600000000001e-08 11865000.0 17118.0 14531.0 19306.0 22979.0 20332.0 20162.0 20742.0 21916.0 22314.0 17707.0 True False 20015.739304088755 15973.541647966553 19766.328258412726 21691.561128923175 16348.090554483226 19104.669226827504 18777.16760092442 21340.72822192145 22640.300036059438 20917.13893146512 0.9569061700871331 0.7636580557361963 0.9449824052504017 1.0370233328752771 0.7815643720705612 0.9133500183473389 0.8976929236090889 1.0202508235875 1.0823803441876179 1.0 14.352397911264983 -7.802051405925584 4.339276226604918 1.0437512792679344 0.8965970458368242 0.38842255499615985 0.07770700420167484 0.2120361076758825 8.598153633702522 0.044124566695383664 0.020979061173440474 1.577424544397918e-08 7.802051405925584 -0.14715423343111023 TREEECHFYAGGQVYPGEASR ddPTM_PC-9_AZD4547_30min_R2 1 TREEECHFYAGGQVYPGEASR 21 1 Q13162;A6NG45 Q13162 PRDX4 Peroxiredoxin-4 0 90.01700000000001 0.00019130000000000001 6494800.0 32566.0 28793.0 40562.0 55775.0 42162.0 36331.0 29031.0 45888.0 38579.0 47529.0 False True 42921.310585119965 38099.77417219667 40024.121377259995 42916.93546515999 36308.53406909525 34059.21682668733 31614.702759500968 38797.0640013378 40618.20717941054 45865.024176701656 0.9358178994904569 0.830693428295421 0.8726501750671986 0.9357225082846632 0.7916388298240367 0.74259672676655 0.6892987265786832 0.8458965125989356 0.8856030909941965 1.0 15.485106779775515 TREIFTNLAPFSEVS(ph)ADGEK ddPTM_PC-9_Lapatinib_30min_R1 1 TREIFTNLAPFSEVSADGEK 20 1 A0A3B3IRE4;Q8TCE6-2;Q8TCE6;Q6NSW5 A0A3B3IRE4 FAM45A;FAM45B Protein FAM45A;Protein FAM45B 1 TREIFTNLAPFS(0.001)EVS(0.999)ADGEK 51.535 0.019946000000000002 7377000.0 16058.0 20249.0 19710.0 29181.0 31302.0 17577.0 20687.0 25408.0 21452.0 32328.0 True False 15829.009975323463 20202.11468459485 18089.519882800214 31327.068084962346 29460.877902099797 16825.272683988253 21758.071637731613 26588.548436464258 19035.84986042543 37915.85172564772 0.4174773677737567 0.5328144764035295 0.47709649287830125 0.826226147091179 0.7770068865991303 0.443752992962756 0.5738515857475418 0.7012515142440742 0.5020551825702193 1.0 15.210513510921453 -12.111134066442094 2.067541521924503 7.733109542561025 0.5907822827747453 0.4659228239225788 0.13357132513620645 6405178.681304401 202288.3976472363 203589845.20987847 0.03538885025919349 7.742227588146488e-13 12.111134066442094 -7.1423272597862795 TRGIS(ph)LGLFALCLAAAR ddPTM_PC-9_AZD4547_30min_R2 1 TRGISLGLFALCLAAAR 17 1 A8MXK1 A8MXK1 VSTM5 V-set and transmembrane domain-containing protein 5 1 TRGIS(1)LGLFALCLAAAR 52.298 0.032471 23149000.0 76871.0 80964.0 96463.0 96552.0 98705.0 103120.0 86436.0 123590.0 113700.0 100520.0 True False 101314.37898387166 107134.02966268643 95183.83759219556 74293.42811352981 85001.51452231986 96671.89009848336 94128.6365512803 104492.0053156675 119709.94987684957 97000.82539590694 1.0444692462188754 1.1044651344503618 0.9812683263642822 0.7659051127689136 0.8762968168094227 0.9966089433148528 0.9703900576834903 1.0772280018152984 1.234112693250349 1.0 16.565709403029786 -7.832255085580875 3.5502118878471083 1.1276634425938128 0.9583006309852402 0.2916727396447618 0.10125655210765082 0.30199909372373085 7.48124792585218 0.06672983270958716 0.03004756445074536 1.4714479843885815e-08 7.832255085580875 -0.16936281160857258 TRHS(ph)PTPQQSNR ddPTM_PC-9_AZD4547_30min_R2 2 TRHSPTPQQSNR 12 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 T(0.051)RHS(0.933)PT(0.016)PQQSNR;T(0.001)RHS(0.955)PT(0.012)PQQS(0.032)NR 74.649 0.0086832 183758100.0 14500.76 12810.52 14752.46 19228.0 20096.46 15701.84 13777.0 16158.0 18244.87 20446.48 True False 19111.700045454905 16951.270066627607 14556.832741313872 14795.281669638653 17306.413419150187 14720.001462606375 15003.12631041454 13661.152373902041 19209.256580559668 19730.65495862415 0.9686297837315987 0.8591336730673662 0.7377774722552314 0.7498626731177884 0.8771332454722016 0.7460472799040233 0.7603967705013647 0.69238210300418 0.9735741981623077 1.0 14.268151226633517 -8.374384190805324 6.6103686934201455 0.996657721858552 0.797080874700023 0.48338602226657823 0.07779171480231266 0.21918471079813004 10.949532085002364 0.07762401976732737 0.02011401572421475 4.222948734110022e-09 8.374384190805324 -0.19957684715852897 TRHS(ph)PTPQQSNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TRHSPTPQQSNR 12 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 T(0.237)RHS(0.759)PT(0.004)PQQSNR;T(0.061)RHS(0.922)PT(0.015)PQQS(0.002)NR;T(0.139)RHS(0.846)PT(0.012)PQQS(0.003)NR 89.13600000000001 0.0036121 1266710000.0 15742.6 18336.350000000002 21048.2 25955.5 26329.0 30674.2 18036.460000000003 21209.2 22978.0 19623.600000000002 True False 18407.51124947702 20156.661647284534 21550.068913743016 24501.297483866354 21170.021454307935 29065.590953157036 16327.915936137751 20652.480973004942 23314.00977989485 23181.20333966788 0.794070565697421 0.8695261135470166 0.9296354722391114 1.0569467479688388 0.9132408332781243 1.2538430610036424 0.7043601532193662 0.890914965473955 1.0057290572142004 1.0 14.50066783834902 -5.104026302892224 2.1616024852876197 0.9688801551367192 0.7951685170590785 0.1643741128053522 0.13090902245571134 0.739646337777221 5.913758484992035 0.03607125518134306 0.19028074527274724 7.86998123987692e-06 5.104026302892224 -0.17371163807764067 TRHS(ph)PTPQQSNR ddPTM_PC-9_Lapatinib_30min_R1 9 TRHSPTPQQSNR 12 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 T(0.019)RHS(0.964)PT(0.007)PQQS(0.01)NR;T(0.006)RHS(0.99)PT(0.003)PQQS(0.001)NR;T(0.002)RHS(0.996)PT(0.001)PQQS(0.001)NR;T(0.048)RHS(0.914)PT(0.037)PQQSNR;T(0.06)RHS(0.924)PT(0.009)PQQS(0.007)NR;T(0.114)RHS(0.763)PT(0.09)PQQS(0.033)NR;T(0.295)RHS(0.657)PT(0.01)PQQS(0.039)NR;T(0.087)RHS(0.899)PT(0.006)PQQS(0.008)NR;T(0.319)RHS(0.67)PT(0.01)PQQS(0.001)NR 115.09 0.00034853 4242168500.0 21372.51 14764.720000000001 20110.579999999998 20742.33 20690.57 17299.94 20874.96 22533.15 24419.509999999995 17397.839999999997 True False 21067.73408816167 14730.5331979817 18457.165741483746 22267.790142584476 19473.59135182573 16560.061894329832 21955.763286836278 23580.122410308373 21669.12763495977 20405.033462835403 1.0324773113718864 0.721906838565645 0.9045398418532665 1.0912890774299289 0.9543523360201221 0.8115674950737725 1.0759974163642165 1.1556032217862275 1.0619501151236392 1.0 14.316637456066909 -7.363479434295056 8.04752140779528 1.087821254311662 0.9192816256987542 0.34341448413262554 0.10365224137930659 0.3431596793185016 24.321804331039306 0.04492721289472389 0.030193442717262 4.330325732006486e-08 7.363479434295056 -0.16853962861290794 TRHSPTPQQS(ph)NR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TRHSPTPQQSNR 12 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 T(0.007)RHS(0.143)PT(0.082)PQQS(0.768)NR 83.292 0.005275899999999999 680420000.0 3249.2 5933.6 9285.8 8777.0 11534.0 9062.6 8783.5 9549.3 10262.0 7098.3 True False 3799.2253853747648 6522.64859420373 9507.208688592602 8285.253145417928 9273.995497511782 8587.341302204493 7951.4632929669015 9298.640993319692 10412.06233620337 8385.16559988812 0.45308889134228386 0.7778795202674065 1.1338128717123312 0.9880846176166723 1.1060002795455253 1.024111116221613 0.9482774309278991 1.1089394577304186 1.2417241153045675 1.0 13.03362356073295 -4.932401613754441 2.446126536479198 1.0656413006429297 0.4061936318004644 0.8455912031102953 0.08303522857704301 0.14236644991845399 1.3614987745574825 0.022381499958037326 0.17454307473821215 1.168418396542104e-05 4.932401613754441 -0.6594476688424653 down TRHSPTPQQSNR ddPTM_PC-9_AZD4547_30min_R2 1 TRHSPTPQQSNR 12 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 0 106.26 0.0023283 0.0 477.77 0.0 762.31 456.27 540.37 662.89 584.59 518.26 618.91 0.0 False True 629.6909217666514 0.0 752.2012713154944 351.0840008012288 465.3489529651582 621.4393835083754 636.6173774991104 438.17482543003246 651.6243190701923 0.0 0.0 TRHSPTPQQSNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TRHSPTPQQSNR 12 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 0 138.24 0.00013241 0.0 0.0 0.0 0.0 0.0 0.0 0.0 457.52 0.0 0.0 0.0 False True 0.0 0.0 0.0 0.0 0.0 0.0 414.18039344204703 0.0 0.0 0.0 0.0 TRKS(ph)PSSDSWTCADTSTER ddPTM_PC-9_Lapatinib_30min_R1 1 TRKSPSSDSWTCADTSTER 19 2 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHH7;H0YIQ0 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 T(0.252)RKS(0.746)PS(0.001)SDSWTCADTSTER 69.975 0.020676 11134000.0 9166.1 5745.4 9510.6 6060.7 8548.9 7328.8 6449.1 7257.2 8499.8 8003.8 True False 9035.389733143127 5732.096879296323 8728.675179977668 6506.424095902517 8046.070509784075 7015.364308267226 6783.002842311353 7594.396005711134 7542.463017137981 9387.24616560688 0.9625176088645795 0.6106260321901067 0.929844069920943 0.6931131858180988 0.8571278911661416 0.7473293215608016 0.7225764321769903 0.8090121289815095 0.8034798367994396 1.0 13.19648627684199 -9.047874535030894 1.7535512395908717 0.9999767176204714 0.7853954580804057 0.27334689282709224 0.10116586836822083 4.989563271862993 15.372117340627167 0.08735442357989125 0.02454427672953503 8.956234682170447e-10 9.047874535030894 -0.21458125954006568 TRLPPAGS(ph)TPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TRLPPAGSTPR 11 1 J3QSF9 J3QSF9 FDXR 1 TRLPPAGS(0.763)T(0.237)PR 60.167 0.030541000000000002 6373300.0 14727.0 16038.0 15353.0 13834.0 18747.0 17363.0 14934.0 11365.0 14513.0 12667.0 True False 17219.99022849136 17630.146648550523 15719.073746576742 13058.925830433136 15073.659926465525 16452.45371418539 13519.34340720302 11066.680792212868 14725.22516910148 14963.426828083178 1.150805255128664 1.178215849290784 1.050499589911809 0.8727229384330802 1.0073668351273295 1.0995110881491146 0.9034924661662447 0.7395819767329671 0.9840810756975372 1.0 13.869152989382746 -5.499272849408247 3.752096025982534 0.9405892628963002 1.1606100686606002 0.4858818777038272 0.0908596101842968 0.19943039089235423 6.024152942359027 0.026948094458512973 0.056211707742773065 3.1675767792198933e-06 5.499272849408247 0.22002080576430005 TRLS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TRLSPPR 7 1 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 T(0.004)RLS(0.996)PPR 56.013000000000005 0.043845999999999996 214210000.0 4563.1 7301.2 5813.9 6492.0 6919.6 6583.3 7581.6 6477.2 6189.6 6089.2 True False 5335.542704666867 8026.014884050198 5952.525425338532 6128.27428734798 5563.754052764226 6238.060158762695 6863.415961969364 6307.1803631606845 6280.111190427243 7193.123757919321 0.7417559997897525 1.1157899063274004 0.8275299613446879 0.8519628597521366 0.7734823200614018 0.8672254737581649 0.9541634751401346 0.8768346792611137 0.873071477953248 1.0 12.812402710593743 -7.219982610696697 22.266128836619192 0.9157536411347316 0.8682728881647526 0.08210114171072103 0.10004637335143032 505.35431554326584 271421.0574301638 0.038158079925687816 0.029556285934383655 6.025837132544469e-08 7.219982610696697 -0.047480752969979 TRLS(ph)TASEETVQNR ddPTM_PC-9_AZD4547_30min_R2 4 TRLSTASEETVQNR 14 1 O43379;O43379-4;H7C3R4;O43379-3;O43379-2 O43379 WDR62 WD repeat-containing protein 62 1 T(0.018)RLS(0.95)T(0.024)AS(0.001)EET(0.006)VQNR;T(0.467)RLS(0.493)T(0.021)AS(0.003)EET(0.015)VQNR;T(0.058)RLS(0.459)T(0.459)AS(0.021)EET(0.002)VQNR;T(0.081)RLS(0.762)T(0.153)AS(0.003)EET(0.001)VQNR 152.34 0.00028224 37410900.0 51487.0 52908.6 79916.0 101070.0 88555.0 70528.0 56355.6 73273.0 60984.0 74210.0 True False 67858.79500387123 70010.27026593577 78856.26162381317 77769.87301593405 76260.6668205665 66117.87301072369 61371.13922473677 61950.34149603443 64207.489738696444 71611.93048776593 0.9475906394600564 0.9776341705785493 1.101160953024229 1.0859904555878455 1.0649156683968288 0.9232801372673394 0.8569960173775977 0.8650840868843486 0.8966032517398138 1.0 16.127912338850415 -6.856583314305649 4.970156739776963 0.8933374801557429 1.038452043663776 0.5502921621174581 0.05707471271608495 0.15677084521004364 6.423436769262381 0.021587831957207013 0.01910578735042385 1.3912868671649104e-07 6.856583314305649 0.1451145635080332 TRLS(ph)TASEETVQNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TRLSTASEETVQNR 14 1 O43379;O43379-4;H7C3R4;O43379-3;O43379-2 O43379 WDR62 WD repeat-containing protein 62 1 T(0.001)RLS(0.957)T(0.035)AS(0.008)EETVQNR;T(0.01)RLS(0.494)T(0.494)AS(0.002)EETVQNR;T(0.009)RLS(0.473)T(0.473)AS(0.045)EETVQNR 160.63 0.00033160000000000004 26728600.0 44515.0 42510.5 54637.6 50838.0 75904.0 72697.0 71811.0 75747.0 74491.0 61613.0 True False 52050.51028867336 46730.661497892914 55940.367598251905 47989.71167901983 61031.15608142314 68884.64134424558 65008.542213382716 73758.72151058055 75580.2899518734 72782.94917176037 0.7151470348616877 0.6420550696237013 0.7685916582775221 0.6593537665775123 0.8385364536053055 0.9464392708474182 0.8931836776766102 1.0134066062164844 1.038434012525538 1.0 16.151312890048494 -6.686234750785836 1.0123949988241017 1.008614275999734 0.6819701826117328 0.8841251352996022 0.048186421438861406 0.1614546017416107 0.35646069234109173 0.02608640009415142 0.025635677365935108 2.0595163744207314e-07 6.686234750785836 -0.32664409338800127 TRLS(ph)TASEETVQNR ddPTM_PC-9_Lapatinib_30min_R1 2 TRLSTASEETVQNR 14 1 O43379;O43379-4;H7C3R4;O43379-3;O43379-2 O43379 WDR62 WD repeat-containing protein 62 1 T(0.33)RLS(0.615)T(0.016)ASEET(0.039)VQNR;T(0.059)RLS(0.561)T(0.379)AS(0.001)EETVQNR 155.57 0.0015949000000000002 16723000.0 20025.5 11049.1 30848.0 21999.0 20816.6 43154.0 35027.0 37245.0 37893.0 31667.0 True False 19739.932697773063 11023.516487804678 28311.79651672354 23616.87984651269 19592.208515010254 41308.40401688734 36840.52667157275 38975.5386695573 33625.09130902018 37140.59875637483 0.531492042636628 0.29680502891495786 0.7622870245694165 0.6358777358821949 0.527514611262088 1.1122169647250812 0.9919206449316982 1.0494052324040017 0.9053459673492408 1.0 15.180709453193533 -6.755888392391444 24.99918915438149 1.013624537832374 0.5531609909452747 0.7904777316445625 0.11866051778461462 63.48980315433512 285929.7813278921 0.04133334684303298 0.04022167926156426 1.7543312825236721e-07 6.755888392391444 -0.46046354688709934 TRMYSLRPEPPDTGVS(ph)HLCPEPPK ddPTM_PC-9_Lapatinib_30min_R1 1 TRMYSLRPEPPDTGVSHLCPEPPK 24 2 Q5HY64 Q5HY64 FAM47C Putative protein FAM47C 1 TRMYSLRPEPPDT(0.021)GVS(0.979)HLCPEPPK 54.441 0.035761 0.0 3341.0 7758.8 2301.3 6292.0 6201.2 4720.2 6648.5 10098.0 4128.4 6526.6 True False 3293.356727335636 7740.834975299249 2112.0959972748947 6754.7346694967 5836.457608028285 4518.328049323623 6992.726798639662 10567.189944561407 3663.4161180207107 7654.714113852151 0.43023902373779055 1.0112506959980716 0.2759209509147828 0.8824280788322548 0.7624657852951678 0.590267380612837 0.913519002099041 1.380481333122392 0.4785830095720109 1.0 12.902132782017505 -7.371284190550658 5.525838232959489 0.9826412593212438 0.6731141836897491 0.19115446175030137 0.2835190706110327 0.36121991294528627 15.414213929841344 0.11395992981225432 0.07579724414320409 4.253200041566292e-08 7.371284190550658 -0.30952707563149473 TRNS(ph)GIWESPELDR ddPTM_PC-9_AZD4547_30min_R2 3 TRNSGIWESPELDR 14 1 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 T(0.011)RNS(0.989)GIWESPELDR;TRNS(0.995)GIWES(0.005)PELDR;T(0.016)RNS(0.984)GIWESPELDR 132.14 6.8506e-05 30656900.0 29473.800000000003 42014.0 46160.0 46012.0 46406.0 44039.0 37425.1 50658.0 40789.0 39944.0 True False 38845.855306875535 55594.20387145039 45547.88823959182 35404.644278313586 39963.32792586772 41285.23436818375 40755.86139797458 42829.97010503339 42945.0232676061 38545.57271800737 1.0077903262993386 1.4422980371356213 1.1816632891360093 0.9185138987900824 1.0367812723456569 1.0710759098125033 1.057342219199525 1.1111514782351248 1.1141363388678729 1.0 15.234277543591858 -5.535529527751284 24.135002927589003 1.050135769933574 1.2467782967646917 0.3201372849197477 0.11120651318676429 142.16760241528362 271224.34062677826 0.028751907813512355 0.0498470921790984 2.913872013411505e-06 5.535529527751284 0.1966425268311176 TRNS(ph)GIWESPELDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TRNSGIWESPELDR 14 1 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 T(0.089)RNS(0.911)GIWESPELDR;T(0.017)RNS(0.98)GIWES(0.003)PELDR;TRNS(0.972)GIWES(0.028)PELDR 147.53 0.00099239 30773300.0 22640.9 35027.0 36104.0 32866.5 34184.7 34882.0 29620.1 32170.2 36365.8 24135.0 True False 26473.55719184151 38504.249074621475 36964.856285182475 31025.096559630663 27486.453431922222 33052.72651374848 26814.269697046617 31325.76633714442 36897.58102766561 28510.48444744514 0.9285551510231823 1.350529456824852 1.2965355377710863 1.0881995574933438 0.9640823004109044 1.159318305329967 0.9405055794991753 1.0987454946578983 1.2941758704830444 1.0 14.799204933170763 -5.881175734994603 8.320824158308833 1.0738377363257898 1.2072881284065877 0.11864781105413724 0.14069682313396412 0.46038891395586323 31.490647050454488 0.039288556383656824 0.058461583677454854 1.3146927409920488e-06 5.881175734994603 0.1334503920807979 TRNS(ph)GIWESPELDR ddPTM_PC-9_Lapatinib_30min_R1 2 TRNSGIWESPELDR 14 1 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 T(0.009)RNS(0.991)GIWESPELDR;T(0.001)RNS(0.999)GIWESPELDR 118.66 5.3005e-05 24731000.0 14644.7 16042.4 14275.6 13603.3 14949.7 17083.1 16915.3 16283.099999999999 17381.2 13444.900000000001 True False 14435.863892490943 16005.254808442114 13101.915273409588 14603.732061278506 14070.38803824106 16352.49563565111 17791.091466801452 17039.672270379062 15423.546223849817 15768.833050796868 0.9154681165047553 1.014992977405725 0.8308741192961956 0.9261136835068792 0.8922910143645679 1.0370136828117884 1.1282440120641894 1.0805918367889609 0.9781032099309592 1.0 13.944788279112167 -6.822084993833316 5.8954038386081535 1.056717152479421 0.9173719256285588 0.5539150779421944 0.05744362892596917 0.14825536327439295 10.11874365234894 0.020516446543473753 0.01824362972383819 1.5063122436970798e-07 6.822084993833316 -0.13934522685086215 TRNSGIWES(ph)PELDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TRNSGIWESPELDR 14 1 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 TRNS(0.222)GIWES(0.778)PELDR 151.38 0.0011724 7456100.0 9103.0 10430.0 9920.6 10063.0 11289.0 11066.0 11632.0 12863.0 7966.4 9728.9 True False 10643.958107554618 11465.421470531353 10157.14472808501 9499.202734686187 9077.001488764572 10485.679479420358 10530.1327516128 12525.359879475061 8082.893529051885 11492.672556069974 0.9261516897506056 0.9976288295515539 0.8837931019552461 0.8265442775248203 0.7898077183074758 0.9123795556049527 0.9162475220832078 1.0898561512447915 0.7033084332314697 1.0 13.488426707128358 -9.372428736353756 13.21112118028457 1.00000549435393 0.898629676295113 0.08784621405557269 0.10150583292584416 0.0 0.0 0.09720803932486968 0.02357641257621371 4.242005855324819e-10 9.372428736353756 -0.10137581805881701 TRPGS(ph)FQSLSDALSDTPAK ddPTM_PC-9_AZD4547_30min_R2 3 TRPGSFQSLSDALSDTPAK 19 1 G3V4K3;Q9H9C1-2;Q9H9C1 G3V4K3 VIPAS39 Spermatogenesis-defective protein 39 homolog 1 T(0.03)RPGS(0.97)FQSLSDALSDTPAK;T(0.047)RPGS(0.429)FQS(0.429)LS(0.095)DALSDTPAK;T(0.055)RPGS(0.695)FQS(0.23)LS(0.02)DALSDTPAK 203.23 1.3165999999999997e-19 45002400.0 62993.8 60182.0 85846.0 115130.0 112030.0 105182.0 76198.0 106183.0 92063.0 101237.0 True False 83024.51804756293 79634.65457684651 84707.62594922006 88588.55724076854 96476.56827856206 98604.95291251638 82979.47438491473 89774.85719260064 96929.26222966047 97692.7234441445 0.8498536546074685 0.8151544124202594 0.8670822448475538 0.9068081441236384 0.9875512205750127 1.009337742220826 0.8493925797079245 0.9189513202989895 0.9921850759445708 1.0 16.575963487884366 -5.805946158301508 2.4041423920142373 0.9521122869624965 0.834804273020678 0.5564440907711827 0.0461551196484742 0.23649779973910667 2.787253149503476 0.014589045457879778 0.025981816633643958 1.5633414460274213e-06 5.805946158301508 -0.11730801394181856 TRPGS(ph)FQSLSDALSDTPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TRPGSFQSLSDALSDTPAK 19 1 G3V4K3;Q9H9C1-2;Q9H9C1 G3V4K3 VIPAS39 Spermatogenesis-defective protein 39 homolog 1 T(0.007)RPGS(0.993)FQSLSDALSDTPAK;TRPGS(0.979)FQS(0.015)LS(0.005)DALSDTPAK;T(0.042)RPGS(0.888)FQS(0.061)LS(0.008)DALSDTPAK;T(0.026)RPGS(0.786)FQS(0.093)LS(0.093)DALS(0.003)DTPAK;T(0.024)RPGS(0.85)FQS(0.09)LS(0.036)DALSDTPAK 160.67 1.6201e-05 61562900.0 214478.0 185252.0 179200.0 186886.0 238499.0 197046.0 156614.0 214240.0 144754.0 117818.0 True False 250784.88926640616 203642.59427218372 183472.80761978432 176415.38331258716 191766.8330293972 186712.56088034174 141778.38813283082 208616.4270060433 146870.75340233676 139177.4707532249 1.8019072189569534 1.4631864853562524 1.3182651375027452 1.2675570432328713 1.3778582984125236 1.3415429944937076 1.0186877758701163 1.498923826370867 1.0552767815615274 1.0 17.086566169365256 -1.5228787452803383 0.5895491263057829 1.2159229961696358 34.53104689529143 0.593194800135352 0.15015860166288839 114.84234912097892 0.9227341199025408 0.06564775662148074 4912.6744088089 0.02999999999999995 1.5228787452803383 33.315123899121794 TRPGS(ph)FQSLSDALSDTPAK ddPTM_PC-9_Lapatinib_30min_R1 3 TRPGSFQSLSDALSDTPAK 19 1 G3V4K3;Q9H9C1-2;Q9H9C1 G3V4K3 VIPAS39 Spermatogenesis-defective protein 39 homolog 1 T(0.002)RPGS(0.969)FQS(0.014)LS(0.014)DALSDTPAK;T(0.022)RPGS(0.931)FQS(0.043)LS(0.003)DALSDTPAK;T(0.047)RPGS(0.467)FQS(0.414)LS(0.072)DALSDTPAK 106.72 0.00010192 40997100.0 260869.0 238359.0 237236.0 226951.0 183985.0 152146.0 176244.0 185200.0 192090.0 212053.0 True False 257148.96022248434 237807.09438023332 217731.37183744297 243641.73362634232 173163.36402842737 145639.07024964885 185369.05195148505 193805.06810584044 170454.8014026253 248706.07850713897 1.0339472270481842 0.956177250703614 0.8754565756670604 0.9796372291694861 0.6962570640325416 0.5855870959159865 0.7453338216104924 0.7792534435392876 0.6853664471161387 1.0 17.924082242646797 -6.260176820970519 24.99538042196719 0.7292783947745792 0.9548063418066891 0.48457725613262437 0.1062494478031377 92.42185867212021 1829709.8748808804 0.031178482673494372 0.03804734661468752 5.493171763985031e-07 6.260176820970519 0.22552794703210988 TRPGSFQS(ph)LSDALSDTPAK ddPTM_PC-9_AZD4547_30min_R2 2 TRPGSFQSLSDALSDTPAK 19 1 G3V4K3;Q9H9C1-2;Q9H9C1 G3V4K3 VIPAS39 Spermatogenesis-defective protein 39 homolog 1 T(0.1)RPGS(0.1)FQS(0.717)LS(0.082)DALSDTPAK;T(0.004)RPGS(0.123)FQS(0.85)LS(0.023)DALSDTPAK 97.94 0.00027312 39919600.0 106148.0 105047.0 130476.0 188332.0 203555.0 144210.0 147309.0 199447.0 144189.0 156366.0 True False 139900.85598444138 139001.38844395324 128745.80298849611 144914.9671003946 175294.90186506105 135192.5259028539 160419.21562465368 168627.0489861148 151810.5361723224 150891.67393410637 0.9271608720142861 0.9211998569560202 0.8532333138852893 0.9603907447118536 1.1617268023788474 0.8959574930681184 1.0631415998122464 1.1175371350161665 1.0060895489741688 1.0 17.20315367589204 -6.006488152563392 24.214746633331476 1.0423687094421967 0.9033004707347436 0.4549728774318329 0.06947813742947027 174.4159737553389 650954.3069955865 0.019379662981416395 0.027594479003868234 9.85171517651379e-07 6.006488152563392 -0.1390682387074531 TRPLQFR ddPTM_PC-9_Lapatinib_30min_R1 1 TRPLQFR 7 1 P30838;A8MYB8;C9JMC5;E9PNN6;C9JKT2;I3L3W9;I3L4E5;I3L1H6 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 0 90.777 0.020352000000000002 6411000.0 22290.0 26018.0 22055.0 25091.0 25615.0 25706.0 22205.0 22516.0 26005.0 23248.0 False True 21972.140512514627 25957.756919541152 20241.723034761988 26936.27584112232 24108.376061027626 24606.614303612794 23354.66625010056 23562.175558699208 23076.043055209917 27266.38582398719 0.8058325241325152 0.952005780564625 0.742369126785943 0.9878931522132844 0.8841793781051336 0.9024523624970309 0.8565369242869968 0.8641473685144857 0.8463183644569834 1.0 14.734835862370835 -12.168179993847643 2.0533036470237858 3.6641911278628188 0.8739643816183383 0.25611853418567543 0.06565804972567357 2969447.780273577 134325.46708272974 37021214.82319337 0.015263710649243338 6.78922194215545e-13 12.168179993847643 -2.7902267462444805 TRPWLQELSMGS(ph)PGPVTNK ddPTM_PC-9_AZD4547_30min_R2 1 TRPWLQELSMGSPGPVTNK 19 1 A0A1B0GV70;Q96N21;Q96N21-2 A0A1B0GV70 ENTHD2 AP-4 complex accessory subunit tepsin 1 TRPWLQELSMGS(0.928)PGPVT(0.072)NK 95.13799999999999 0.0010232999999999998 0.0 19714.0 15949.0 23068.0 33617.0 26530.0 25502.0 23262.0 30970.0 20394.0 27933.0 True False 25982.64192332662 21104.202350306157 22762.10324763655 25867.120027472567 22846.76744113413 23907.355908567923 25332.272935534827 26184.2981198011 21471.98520482383 26955.074172143493 0.9639239631615696 0.7829398730468391 0.8444459511508177 0.959638243333225 0.8475868882878066 0.8869334120873905 0.9397960760098469 0.9714051592876363 0.7965841632524197 1.0 14.718269258980689 -14.522878745278463 0.18082074499239686 1.438962746973729 0.8669126095737735 0.17634609879186214 0.06713622557038901 225.9393246216277 2.1718071514896056 35.88595457415953 0.2030391616344451 3.0000000000129466e-15 14.522878745278463 -0.5720501373999555 TRPWLQELSMGS(ph)PGPVTNK ddPTM_PC-9_Lapatinib_30min_R1 1 TRPWLQELSMGSPGPVTNK 19 1 A0A1B0GV70;Q96N21;Q96N21-2 A0A1B0GV70 ENTHD2 AP-4 complex accessory subunit tepsin 1 TRPWLQELSMGS(1)PGPVTNK 114.66 3.6921e-05 4896900.0 24367.0 19438.0 17233.0 17895.0 22004.0 19224.0 18220.0 19234.0 19717.0 12940.0 True False 24019.52211163948 19392.992505267157 15816.169261303712 19211.057995970034 20709.767981528483 18401.83433333277 19163.342448855314 20127.68185716916 17496.26383078539 15176.661758533814 1.5826617535396634 1.2778167434852732 1.0421375604823178 1.2658289617061331 1.364579926141097 1.2125086943435004 1.2626849536315057 1.3262258971971483 1.1528400717600014 1.0 13.889566871617863 -14.522878745280044 0.14168424122304246 0.07448105721234104 1.3640308709802391 0.3461989474483196 0.1271616637909766 184.6088381484118 1.588614236121104 48.31474763544732 0.7921900489801877 3.0000000000020256e-15 14.522878745280044 1.289549813767898 TRS(ph)EGGGTGESSQGGTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TRSEGGGTGESSQGGTSK 18 1 F5H0R1;Q9H6E5 F5H0R1 TUT1 Speckle targeted PIP5K1A-regulated poly(A) polymerase 1 T(0.058)RS(0.935)EGGGT(0.007)GESSQGGTSK 140.88 7.5365e-05 3614500.0 9438.6 8710.9 12003.0 8964.0 13274.0 12453.0 16628.0 13003.0 14147.0 9530.1 True False 11036.368559152479 9575.660583667459 12289.197041630989 8461.776141680113 10673.054988206293 11799.9427577464 15052.87546370509 12661.68502781732 14353.873111505456 11257.831689769908 0.9803280829985517 0.850577699821978 1.0916131436569878 0.7516346286620544 0.94805600956932 1.0481541279808892 1.3371025503413567 1.1247001533450804 1.2750122321111754 1.0 13.458641364014609 -6.964362716388336 3.601925971660461 1.1957185267505 0.9211863081139704 0.5175397071569439 0.11747668106192756 0.171324017310149 4.701303796236605 0.042199070467727515 0.0354413070348676 1.0855186356579449e-07 6.964362716388336 -0.27453221863652955 TRS(ph)EGGGTGESSQGGTSK ddPTM_PC-9_Lapatinib_30min_R1 1 TRSEGGGTGESSQGGTSK 18 1 F5H0R1;Q9H6E5 F5H0R1 TUT1 Speckle targeted PIP5K1A-regulated poly(A) polymerase 1 T(0.392)RS(0.608)EGGGTGESSQGGTSK 106.75 0.0001471 2349000.0 8125.4 8373.6 11552.0 8082.1 12900.0 11387.0 11306.0 11853.0 14303.0 11618.0 True False 8009.530305984133 8354.211443672451 10602.239152009543 8676.484595095244 12141.24736237581 10900.00455439348 11891.369359317134 12403.733651503891 12692.045522732838 13626.155819988095 0.5878055712701464 0.6131011236065368 0.7780799876409168 0.6367521926006292 0.8910251374467563 0.7999324753357329 0.8726870231348582 0.9102885520587515 0.9314472614583624 1.0 13.73409098925857 -4.24124868342831 0.22324537654364873 1.023777223987902 0.07238196207924931 0.8438343749302721 0.05447931051724345 5.404497066294397 0.19575900618398268 0.0885432073263587 1.4789473903427728 5.73787808754924e-05 4.24124868342831 -0.9513952619086526 TRS(ph)EPLPPSATAPPPPGPMQPR ddPTM_PC-9_Lapatinib_30min_R1 1 TRSEPLPPSATAPPPPGPMQPR 22 1 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;Q8WUI4-10 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 T(0.24)RS(0.76)EPLPPSATAPPPPGPMQPR 99.31299999999999 0.00016723 12997000.0 30583.0 21108.0 31995.0 21150.0 22220.0 25182.0 11212.0 23486.0 26394.0 9241.9 True False 30146.880811764684 21059.12572287165 29364.494604271593 22705.441554331726 20913.063286200802 24105.024562109124 11792.502499262673 24577.24529985831 23421.22977885832 10839.350100942323 2.7812443117917054 1.9428402558047153 2.70906413491698 2.0947235159751707 1.9293650533884608 2.2238440808377935 1.0879344600408734 2.2674094914345164 2.1607595991222928 1.0 13.403990638616213 -7.918109906745592 0.08971080914599265 2.097634830918799e-15 3.682603729847563 0.46520335144271285 0.40754864484389086 11.748070426524329 1.083899625779771 20.770257503327194 21.02817700970031 1.2075082127750634e-08 7.918109906745592 3.682603729847561 TRS(ph)ESPAVR ddPTM_PC-9_Lapatinib_30min_R1 2 TRSESPAVR 9 1 Q9UBC3-4;Q9UBC3-3;Q9UBC3-5;Q9UBC3-2;Q9UBC3-6;Q9UBC3 Q9UBC3-4 DNMT3B DNA (cytosine-5)-methyltransferase 3B 1 T(0.01)RS(0.936)ES(0.054)PAVR;T(0.042)RS(0.888)ES(0.069)PAVR 64.22399999999999 0.02567 5181900.0 25196.9 23527.1 26262.5 18845.7 18122.3 18535.9 18214.0 17881.7 21924.2 13323.6 True False 24837.58758545445 23472.62444545071 24103.298626181684 20231.67564541226 17056.381943812652 17743.162766293324 19157.031798213542 18712.54906235529 19454.865723938976 15626.566507418947 1.5894462531908358 1.5020973695217519 1.5424564708273107 1.294697439505151 1.0914990145605483 1.1354485809707136 1.225927127953441 1.197483084558033 1.244986588365556 1.0 13.931713201593164 -5.889402852956327 3.1454741648931717 1.1629865036247076 1.544333445212771 0.8628267205078214 0.07026405050846544 0.08624998234994163 1.6991814060980501 0.020492021090585805 0.03252721008290584 1.2900220898096664e-06 5.889402852956327 0.3813469415880635 TRS(ph)LPITIEMLK ddPTM_PC-9_AZD4547_30min_R2 1 TRSLPITIEMLK 12 1 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 T(0.01)RS(0.781)LPIT(0.209)IEMLK 66.023 0.037563 0.0 215230.0 189660.0 239870.0 293540.0 265180.0 231940.0 214390.0 237560.0 215740.0 220070.0 True False 283668.6629378915 250963.88599655556 236689.16707172644 225868.88814779127 228364.33433999095 217436.75513423464 233470.29467153733 200850.5605857268 227143.57595806097 212365.416284095 1.3357573370534566 1.1817549692781657 1.1145372500534267 1.0635860212080472 1.0753367395494056 1.0238802482008436 1.0993800156199114 0.9457781031400894 1.0695883535678723 1.0 17.69618931676621 -1.5228787452826567 0.5299412170494712 1.0239879152699523 13.24404045774175 0.8554778584410938 0.038787123841634186 40.24719572068813 0.39224550866301616 0.0187889612147332 555.2234968596523 0.029999999999839804 1.5228787452826567 12.220052542471798 TRS(ph)LSSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TRSLSSLR 8 1 H0Y9X0;A0A286YEZ9;A0A2C9F2R7;O94915 H0Y9X0 FRYL Protein furry homolog-like 1 T(0.294)RS(0.666)LS(0.036)S(0.004)LR 58.63 0.036287 11037000.0 5681.2 3628.7 6621.3 9238.7 7545.5 8321.3 9138.1 11465.0 9419.5 6615.4 True False 6642.914951185248 3988.9333547571537 6779.176903420089 8721.085591269533 6067.0134408249705 7884.916379188558 8272.473013885226 11164.055898171633 9557.242367556772 7814.719652522416 0.8500516008966572 0.5104384459229597 0.8674881767808423 1.1159818879049055 0.7763571453093233 1.008982628908957 1.058575787963815 1.4285932694422538 1.2229795555713772 1.0 12.931978403162736 -6.457953834954789 0.6402133221072318 1.2280982071154627 0.6905918026082896 0.4819910756968626 0.17296385264167155 0.6961143790364896 0.6266600191314642 0.1280881499196463 0.19278020787398228 3.483743448931592e-07 6.457953834954789 -0.5375064045071731 TRS(ph)NPEGAEDR ddPTM_PC-9_AZD4547_30min_R2 1 TRSNPEGAEDR 11 1 M0R3H9;M0QXG9;M0R3F4;M0R2A4;M0R2K3;M0R193;M0R0I0;J3KQS6;Q9NWV8-3;Q9NWV8;M0R2I2 M0R3H9 BABAM1 BRISC and BRCA1-A complex member 1 1 T(0.016)RS(0.984)NPEGAEDR 96.866 0.027160000000000004 61354000.0 6821.2 6169.0 10382.0 18748.0 14194.0 8897.8 7954.3 9389.8 8317.1 9768.9 True False 8990.199710226014 8163.008608629923 10244.327896521712 14425.938253712584 12223.408106274326 8341.419159409277 8662.21729047909 7938.822166138468 8756.724926303823 9426.893784421745 0.9536757192578765 0.8659277165209569 1.0867129863551452 1.530296042748665 1.2966527878434266 0.8848534151507838 0.9188835143972547 0.8421461350564525 0.9289088353551412 1.0 13.20256675757304 -6.781759107570435 24.73291537330496 0.9053377344590309 1.1490407003949856 0.3058588918466668 0.1742019027785084 304.202063819063 370268.18737978465 0.07044310782650082 0.062202438987768484 1.65287835483583e-07 6.781759107570435 0.24370296593595475 TRS(ph)NPEGAEDR ddPTM_PC-9_Lapatinib_30min_R1 1 TRSNPEGAEDR 11 1 M0R3H9;M0QXG9;M0R3F4;M0R2A4;M0R2K3;M0R193;M0R0I0;J3KQS6;Q9NWV8-3;Q9NWV8;M0R2I2 M0R3H9 BABAM1 BRISC and BRCA1-A complex member 1 1 T(0.25)RS(0.75)NPEGAEDR 107.65 0.011022 49406000.0 11034.0 9915.7 10552.0 8926.2 8855.4 9433.0 10108.0 10891.0 12800.0 10298.0 True False 10876.653136612218 9892.74080586879 9684.455291897912 9582.6625249303 8334.542782386261 9029.572579397007 10631.342781176161 11397.035619550234 11358.329210024498 12077.995578777538 0.9005346181550008 0.8190714047992783 0.8018263650397953 0.7933984130419924 0.6900600954872872 0.7476052231102841 0.880224099423971 0.943619787340887 0.9404150826137427 1.0 13.560093429535451 -7.547840829280604 3.0054543340088395 0.9572042812310093 0.7896226644601355 0.6756359164821917 0.05263921296904326 0.1717513718222407 3.174940520928746 0.030236581131551123 0.016688394290576395 2.8324299028343634e-08 7.547840829280604 -0.1675816167708738 TRS(ph)PDVISSASTALSQDIPEIASEALSR ddPTM_PC-9_AZD4547_30min_R2 4 TRSPDVISSASTALSQDIPEIASEALSR 28 1 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 T(0.237)RS(0.747)PDVIS(0.006)S(0.001)AS(0.004)T(0.004)ALSQDIPEIASEALSR;T(0.022)RS(0.309)PDVIS(0.309)S(0.309)AS(0.038)T(0.014)ALSQDIPEIASEALSR;T(0.146)RS(0.75)PDVIS(0.042)S(0.041)AS(0.01)T(0.012)ALSQDIPEIASEALSR;T(0.4)RS(0.473)PDVIS(0.04)S(0.04)AS(0.04)T(0.006)ALSQDIPEIASEALSR 98.98 4.988100000000001e-10 49785000.0 33652.6 24042.39 45184.29 52963.4 43273.270000000004 37981.93 39472.05 58152.33 34209.15 38564.84 True False 44353.42678243593 31813.62239293856 44585.11679170938 40753.50640637299 37265.52341151174 35606.91391280343 42984.98598250696 49166.2236061044 36017.37582963613 37214.69668982372 1.1918255616084135 0.854867168691393 1.1980513280362455 1.095091725348307 1.0013657701448342 0.9567971011447223 1.1550540460070742 1.3211507275175185 0.9678266661645263 1.0 15.183584857181176 -7.301062397649765 24.820107302864656 1.1377704449680304 1.0474259463891462 0.033870219781446 0.13229283272599057 1232.7326736273435 772186.6776377746 0.05353817361856357 0.03609585431363158 4.999626972268419e-08 7.301062397649765 -0.09034449857888416 TRS(ph)PDVISSASTALSQDIPEIASEALSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TRSPDVISSASTALSQDIPEIASEALSR 28 1 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 T(0.33)RS(0.381)PDVIS(0.094)S(0.094)AS(0.094)T(0.006)ALSQDIPEIASEALSR;T(0.065)RS(0.578)PDVIS(0.176)S(0.176)AS(0.004)T(0.002)ALSQDIPEIASEALSR 116.05 1.6908e-12 87739300.0 24758.21 26647.2 28439.8 32929.3 37303.0 33979.4 31420.2 32847.8 26471.2 26438.49 True False 28949.28595606281 29292.557910790336 29117.91269054213 31084.37807923103 29993.744931826095 32197.460446685003 28443.851193451228 31985.58005512096 26858.291221409727 31231.578950028335 0.9269235475536707 0.9379147291163056 0.93232278576539 0.9952867938238784 0.9603659481903615 1.0309264382118533 0.9107400954323324 1.0241422665917421 0.8599722500224524 1.0 14.930717887934277 -5.730623123008449 23.562248250141337 0.9696031692317829 0.93293970235938 0.1038409785199137 0.0489378437691537 242.77968541126742 185626.80245419088 0.012312453225174231 0.021321471163882066 1.8594173414373268e-06 5.730623123008449 -0.03666346687240296 TRS(ph)PDVISSASTALSQDIPEIASEALSR ddPTM_PC-9_Lapatinib_30min_R1 1 TRSPDVISSASTALSQDIPEIASEALSR 28 1 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 T(0.249)RS(0.292)PDVIS(0.168)S(0.168)AS(0.062)T(0.062)ALSQDIPEIASEALSR 82.581 6.6497e-05 0.0 1337.9 871.73 1066.2 1048.8 2620.8 2048.0 2073.9 1133.3 1221.1 1072.8 True False 1318.8213006591893 869.711562743932 978.5411516510198 1125.9322506942362 2466.6496966910486 1960.4118141211766 2181.2763943293658 1185.9572553150558 1083.5668592469458 1258.2320505838538 1.0481542733291689 0.6912171426092366 0.7777111950032987 0.8948526229098783 1.9604092071462145 1.5580685718596123 1.7336042213494676 0.9425584531603208 0.8611820520262072 1.0 10.297182301755104 -6.03398206376855 24.875551078181033 1.3753164770882012 0.8262522431738608 0.32859801315462656 0.3415273537524742 670.6934795352735 490960.01774282433 0.10773753302998834 0.13917636586531162 9.247363644832439e-07 6.03398206376855 -0.5490642339143403 TRS(ph)PSPTLGESLAPHK ddPTM_PC-9_Lapatinib_30min_R1 2 TRSPSPTLGESLAPHK 16 1 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 T(0.172)RS(0.662)PS(0.135)PT(0.03)LGESLAPHK;T(0.364)RS(0.444)PS(0.14)PT(0.052)LGESLAPHK 80.596 0.003743 13805100.0 82499.0 53455.0 101380.0 54244.0 93810.0 104625.0 69676.0 81900.0 126943.0 68934.0 True False 81322.54913153629 53331.228231765395 93044.92773811698 58233.28471267942 88292.28023755617 100150.43264278724 73283.48235271369 85705.37299064935 112645.34257094849 80849.15005121863 1.005855337749596 0.6596386999489742 1.1508460840858836 0.7202708337167197 1.0920619472390527 1.238732040835817 0.906422421340088 1.0600652318095398 1.3932780060097936 1.0 16.302944986602284 -6.40308873518329 8.173534505409636 1.1160729803082132 0.8876300550867766 0.28921958734432507 0.17769214626797084 0.3877776387895868 24.516831291085538 0.05326898699378843 0.06037384720837119 3.9528584688972786e-07 6.40308873518329 -0.2284429252214366 TRS(ph)TGQLELGR ddPTM_PC-9_AZD4547_30min_R2 1 TRSTGQLELGR 11 1 E7EUN2 E7EUN2 AGAP1 1 T(0.074)RS(0.463)T(0.463)GQLELGR 79.88600000000001 0.0079178 3622900.0 8407.2 5946.3 8587.9 11883.0 13873.0 9537.6 8824.5 9514.2 7700.6 9079.6 True False 11080.514719376672 7868.325188765776 8474.018834765826 9143.557940519868 11946.973415410997 8941.212364267796 9609.86340467832 8043.999004566083 8107.637994913521 8761.725967615148 1.2646497688163458 0.8980336999637359 0.967163189774168 1.0435795383599118 1.3635410944794524 1.0204852785074607 1.0968002697411487 0.9180838380814571 0.9253471319327665 1.0 13.096999378192498 -7.758283192115818 24.954115305133705 0.9412865949055376 1.0867523715790892 0.20719996483377012 0.12991215509688528 132.537561654138 1047926.2949666317 0.06633914455965406 0.03620001474325783 1.7446841188646423e-08 7.758283192115818 0.14546577667355165 TRS(ph)TGQLELGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TRSTGQLELGR 11 1 E7EUN2 E7EUN2 AGAP1 1 T(0.198)RS(0.401)T(0.401)GQLELGR 77.192 0.0093307 3043000.0 7564.2 6181.3 8246.5 13890.0 13825.0 13005.0 12077.0 10643.0 10107.0 6695.3 True False 8844.669660239986 6794.93861321146 8443.127835025407 13111.788331987593 11116.090493592888 12322.994906005943 10932.979130091806 10363.63252719063 10254.795754434555 7909.104890034358 1.118289589430589 0.8591286508000707 1.067520023114617 1.6578093873187507 1.4054802216113484 1.55807706148052 1.3823282510600656 1.3103420262195573 1.2965810792768495 1.0 12.949298712131213 -5.600379041205535 7.71823991814282 1.3946144603265578 0.9824555171166955 0.4712915839915278 0.1739365166576048 0.17313041326554604 14.77141000847852 0.045482870190032006 0.07911003911591688 2.5096950771783188e-06 5.600379041205535 -0.41215894320986224 TRS(ph)YDNLTTACDNTVPLASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TRSYDNLTTACDNTVPLASR 20 1 G5E953;Q13615-3;Q13615-2;Q13615 G5E953 MTMR3 Myotubularin-related protein 3 1 T(0.24)RS(0.437)Y(0.323)DNLTTACDNTVPLASR 129.51 8.2384e-06 24974000.0 34163.0 28322.0 30582.0 41504.0 49875.0 37891.0 42535.0 44580.0 30442.0 30007.0 True False 39946.12114999325 31133.62098642274 31311.19086288084 39178.66543778351 40102.351780683195 35903.92925670672 38505.77687326775 43409.82223641441 30887.15665939417 35447.03156471869 1.1269242976540979 0.8783139126778335 0.8833233554610437 1.105273522445784 1.1313317366918267 1.0128895896728005 1.0862905911589367 1.224639139589372 0.871360881178466 1.0 15.11337719668502 -5.7732266068793745 24.999956888097877 1.0729378182525442 0.9543998517713435 0.1414521733119377 0.10854107984956743 338.3522521450657 717623.4053564416 0.02960363712173241 0.04431447583526538 1.6856732425620764e-06 5.7732266068793745 -0.11853796648120074 TRSEGGGT(ph)GESSQGGTSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TRSEGGGTGESSQGGTSK 18 1 F5H0R1;Q9H6E5 F5H0R1 TUT1 Speckle targeted PIP5K1A-regulated poly(A) polymerase 1 T(0.291)RS(0.291)EGGGT(0.399)GES(0.013)S(0.005)QGGTSK 70.615 0.0070899 3262200.0 27216.0 31051.0 29764.0 33478.0 36522.0 34277.0 39697.0 41991.0 32383.0 30220.0 True False 31823.13125949756 34133.53807109003 30473.686640598593 31602.336197140434 29365.77627537068 32479.45377879014 35936.612778608454 40888.78074314214 32856.54011238293 35698.64677861163 0.8914380272409643 0.9561577581013709 0.8536370252235022 0.8852530571571847 0.8226019450396869 0.9098231084280138 1.0066659669615095 1.1453874147308045 0.9203861512215216 1.0 15.12358176689099 -7.257312630135749 3.856372213627156 1.0327991842099054 0.8835820711646942 0.5312423439324996 0.06061208126810236 0.1637079287344506 5.603794359825146 0.025000691561542155 0.017590605689167264 5.529519193320973e-08 7.257312630135749 -0.14921711304521112 TRSEPLPPSAT(ph)APPPPGPMQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TRSEPLPPSATAPPPPGPMQPR 22 1 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;Q8WUI4-10 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 T(0.27)RS(0.27)EPLPPS(0.039)AT(0.421)APPPPGPMQPR 68.625 0.0014414999999999999 37280000.0 23717.0 26404.0 28822.0 21709.0 29829.0 32181.0 30172.0 24229.0 21864.0 11509.0 True False 27731.81966789771 29025.214622043157 29509.225788043674 20492.715111527603 23984.221579268164 30493.371708587245 27313.889733636628 23593.01442274753 22183.719637375798 13595.490594806124 2.0397807254187708 2.134914839566852 2.170515700207028 1.50731707463035 1.7641306440556723 2.2429033726989305 2.009040390500607 1.7353558709945158 1.6316968838072403 1.0 13.730840591664133 -8.656777570522866 1.1684551193959674 1.0040590797394129 1.975955162379341 0.6726094542365615 0.20635873195810456 0.4207971745330095 1.1925345895628465 0.2136312413208831 0.0666060455304478 2.2040550090101608e-09 8.656777570522866 0.9718960826399281 TRSES(ph)PAVR ddPTM_PC-9_AZD4547_30min_R2 1 TRSESPAVR 9 1 Q9UBC3-4;Q9UBC3-3;Q9UBC3-5;Q9UBC3-2;Q9UBC3-6;Q9UBC3 Q9UBC3-4 DNMT3B DNA (cytosine-5)-methyltransferase 3B 1 TRS(0.058)ES(0.942)PAVR 57.885 0.038073 2571600.0 9030.9 9267.8 13021.0 21002.0 10204.0 12505.0 11857.0 10742.0 9377.6 13448.0 True False 11902.538345610756 12263.435108293139 12848.333032229739 16160.313377665443 8787.350733861018 11723.060373172366 12912.250029947403 9082.070726603271 9873.28079125016 12977.18961325263 0.9171892143315519 0.944999300601219 0.9900705326142958 1.245286064184662 0.6771381936877269 0.9033589492443328 0.9949958669603695 0.699848811435138 0.7608181035720799 1.0 13.663690361497933 -6.275806182760596 24.99985354458725 0.8353341827146635 1.016264675066057 0.3195363431938052 0.13198508833568984 1030.6609412242585 1793461.7387410144 0.041744707511336195 0.04753712876697484 5.29899875210303e-07 6.275806182760596 0.18093049235139358 TRSPDVIS(ph)SASTALSQDIPEIASEALSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TRSPDVISSASTALSQDIPEIASEALSR 28 1 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 T(0.044)RS(0.044)PDVIS(0.418)S(0.418)AS(0.055)T(0.021)ALSQDIPEIASEALSR 71.524 5.2266000000000004e-05 682910.0 883.61 743.05 829.18 655.85 981.22 732.77 702.71 895.51 1002.3 1271.2 True False 1033.187720906991 816.8150933536268 848.9507958826615 619.1048507943887 788.9569847467069 694.3422512321393 636.1442216201712 872.0038113712753 1016.9567413346942 1501.6584971863363 0.688031082195372 0.5439419780756388 0.5653421183800073 0.41228072291696677 0.525390417478394 0.4623835928962086 0.42362775745092324 0.580693821534758 0.6772223799486836 1.0 10.552341041299954 -8.656376420404996 1.7097219865148576 0.9986088567025175 0.5150682020219323 0.7852470250662609 0.07583782349468268 0.2511198772228284 1.510339113656558 0.07541356630628634 0.021491805663805444 2.206091796096606e-09 8.656376420404996 -0.48354065468058527 TRSPDVISSAS(ph)TALSQDIPEIASEALSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TRSPDVISSASTALSQDIPEIASEALSR 28 1 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 T(0.004)RS(0.012)PDVIS(0.06)S(0.06)AS(0.432)T(0.432)ALS(0.002)QDIPEIASEALSR 77.907 1.2865999999999998e-05 7507300.0 15372.0 18451.0 16550.0 20461.0 25929.0 21816.0 23578.0 21502.0 17069.0 16772.0 True False 17974.175989160667 20282.69334158909 16944.61476622452 19314.636505457023 20848.398582883903 20671.930555126924 21344.52115006246 20937.59528325218 17318.601833624558 19812.630832921048 0.9072079392553174 1.0237253958160355 0.8552430471812468 0.9748648056048899 1.052278153199211 1.0433713084068597 1.077318874512919 1.0567801651288968 0.8741192413905798 1.0 14.274132841685187 -6.003172206076466 24.95592392053992 1.023464393212642 0.9343635297961299 0.26490407474511135 0.0656310413894339 170.46270426864422 1341065.2092914036 0.018483739856568426 0.026814355603313612 9.92722336957156e-07 6.003172206076466 -0.08910086341651202 TRSPDVISSASTALSQDIPEIASEALSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TRSPDVISSASTALSQDIPEIASEALSR 28 1 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 0 84.214 6.681600000000001e-07 877150.0 1025.8 1122.9 2914.8 1127.3 2702.9 3538.6 2007.0 2452.9 2518.7 1083.0 False True 1199.4476795264777 1234.374091012431 2984.299886440557 1064.1410357559116 2173.2861479299986 3353.0295866507213 1816.882430578309 2388.5139740623804 2555.531222587742 1279.3393269767164 0.9375524180601597 0.9648527681310749 2.3326883052152674 0.8317895130064102 1.6987566176565694 2.6209071478905184 1.4201724220202727 1.8669901907157198 1.9975397994110533 1.0 10.321183254447124 -6.506740089464606 24.872398402432207 1.8513141317071893 1.3142959655580961 0.15792110152865224 0.5530372232499418 1200.79209212776 1850626.9396139209 0.17019739339608755 0.1876278130607982 3.1135791512822285e-07 6.506740089464606 -0.5370181661490931 TRSPS(ph)PTLGESLAPHK ddPTM_PC-9_AZD4547_30min_R2 1 TRSPSPTLGESLAPHK 16 1 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 T(0.033)RS(0.183)PS(0.757)PT(0.026)LGES(0.001)LAPHK 76.678 0.0053153 7406500.0 16923.0 11115.0 42599.0 67175.0 51303.0 39607.0 29780.0 41782.0 27785.0 38103.0 True False 22304.161979733013 14707.70638432834 42034.10942630786 51688.841593404235 44180.464004240646 37130.368028807505 32430.362308495693 35325.55195484436 29253.658375798273 36769.02556765057 0.6066019328876705 0.400002615170422 1.1431934563773025 1.4057713196207227 1.2015674422199176 1.0098273602734484 0.8820022235516615 0.9607421303523427 0.7956060277413409 1.0 15.166203323092398 -5.262643168479527 24.99913977050097 1.0591443071247557 0.5033022430808195 0.6258629401447573 0.1689039772417503 69.54025205462025 1444183.122200526 0.04954238393877498 0.11321893632623885 5.462064590852437e-06 5.262643168479527 -0.5558420640439362 TRST(ph)GQLELGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TRSTGQLELGR 11 1 E7EUN2 E7EUN2 AGAP1 1 T(0.217)RS(0.296)T(0.488)GQLELGR 62.035 0.040935 4886400.0 5587.3 6819.2 10572.0 7918.8 11264.0 10511.0 10311.0 9755.1 8729.2 7497.7 True False 6533.119535794783 7496.165109477225 10824.076574533274 7475.13530909599 9056.900059300562 9959.784656442016 9334.267434824591 9499.038961382817 8856.848035976072 8856.97365823945 0.7376243610837843 0.8463573900893004 1.2220965074750865 0.8439830124302147 1.0225727668135407 1.1245132977421293 1.0538890364815665 1.0724926287373642 0.999985816570284 1.0 13.112598112777597 -5.049656542675326 7.15698495879112 1.0406790072537768 0.7629781714615442 0.5564414026024749 0.09173013130169302 0.14465453234595999 18.187006644970864 0.022655370938563287 0.06281446284103116 8.91956053552321e-06 5.049656542675326 -0.2777008357922326 TRST(ph)GQLELGR ddPTM_PC-9_Lapatinib_30min_R1 1 TRSTGQLELGR 11 1 E7EUN2 E7EUN2 AGAP1 1 T(0.002)RS(0.231)T(0.767)GQLELGR 123.95 0.00091816 0.0 11573.0 11979.0 12113.0 12767.0 12731.0 13220.0 11667.0 10310.0 12414.0 10517.0 True False 11407.96689777173 11951.263361487574 11117.115897532167 13705.927769463498 11982.18761010903 12654.611417325175 12271.060172930567 10789.040238505457 11015.804594784699 12334.849436978377 0.9248565988630583 0.9689022490748158 0.9012769839090542 1.1111548494767027 0.9714093123980816 1.0259234603535727 0.9948285332242016 0.8746795243532708 0.8930635636103232 1.0 13.590452485309063 -9.952948592130902 5.162488284306567 0.9999999902781697 0.9660723576301107 0.02484053898109695 0.06713762458930381 93598559.22368781 355378659.7685867 0.35683840030829045 0.0175165055950375 1.1144264415491033e-10 9.952948592130902 -0.03392763264805898 TRSYDNLT(ph)TACDNTVPLASR ddPTM_PC-9_Lapatinib_30min_R1 1 TRSYDNLTTACDNTVPLASR 20 1 G5E953;Q13615-3;Q13615-2;Q13615 G5E953 MTMR3 Myotubularin-related protein 3 1 T(0.027)RS(0.116)Y(0.071)DNLT(0.596)T(0.151)ACDNT(0.039)VPLASR 99.991 0.0034431999999999996 3820300.0 18224.0 13820.0 17067.0 15568.0 16634.0 16413.0 12597.0 13067.0 18527.0 12802.0 True False 17964.122418127696 13788.000639098265 15663.817140525176 16712.922653325593 15655.620823702271 15711.054250571715 13249.21102240562 13674.140523428789 16440.294162040922 15014.808642407263 1.196426997237281 0.9182934639710262 1.043224560070974 1.1130959475648754 1.0426786778677366 1.0463705948404831 0.8824095822963101 0.9107102760409519 1.0949386404837402 1.0 13.874098468003668 -7.063765776465055 15.12620274473046 0.9645344455250022 1.0552419455477906 0.20671702983069729 0.08381052437519704 6.293180899233982 1491.1967130589057 0.03144020631503136 0.024355704281928885 8.634440945573886e-08 7.063765776465055 0.09070750002278838 TRT(ph)FSATVR ddPTM_PC-9_Lapatinib_30min_R1 1 TRTFSATVR 9 1 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 1 T(0.028)RT(0.865)FS(0.058)AT(0.049)VR 86.11399999999999 0.008587000000000001 31112000.0 273550.0 42838.0 57119.0 45277.0 29551.0 46871.0 17370.0 22620.0 60174.0 28795.0 True False 269649.1268370743 42738.811242958895 52422.89630571617 48606.82161964428 27812.86827950137 44866.43659163753 18269.33360793726 23671.00777836988 53396.57045968856 33772.177383074275 7.984357175981651 1.2655035758629665 1.552251005645527 1.4392563756935832 0.823543829111843 1.3285029295778663 0.540958120665722 0.7009026249587675 1.5810816653607154 1.0 15.043547576321465 -4.761203135239892 6.851097978659685 1.1174773997461804 8.144436967468431 0.9732980368853503 0.34032576650895535 0.016815474421664377 4.286893198846643 0.08931087101531808 0.5495507947834956 1.732993224532381e-05 4.761203135239892 7.026959567722251 TRTFS(ph)ATVR ddPTM_PC-9_AZD4547_30min_R2 2 TRTFSATVR 9 1 Q9Y2V2;H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9 Q9Y2V2 CARHSP1 Calcium-regulated heat stable protein 1 1 T(0.005)RT(0.166)FS(0.829)ATVR;T(0.007)RT(0.241)FS(0.75)AT(0.002)VR 97.81299999999999 0.022505 91157000.0 183393.0 126489.0 179781.0 539350.0 443270.0 233203.0 160758.0 245246.0 158482.0 213450.0 True False 241708.15918862895 167374.0956227896 177396.98647318155 415011.19037443376 381729.61189715477 218620.77954457526 175065.15057048903 207348.86589243606 166859.03497258466 205977.18046912312 1.1734705691092906 0.8125856235219208 0.8612458237808247 2.014840621806869 1.8532616624217637 1.0613834942621105 0.8499249779600321 1.0066594047951762 0.8100850521040973 1.0 17.652124989284125 -6.988029002489202 24.982077508591875 0.9227124947816636 1.3374765280172882 0.24250778552688124 0.35847788298342054 385.79016623151074 805095.6932125747 0.1441991596286282 0.1270826924196916 1.0279476487714487e-07 6.988029002489202 0.4147640332356246 TS(ph)ADVEIR ddPTM_PC-9_Lapatinib_30min_R1 2 TSADVEIR 8 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 T(0.226)S(0.774)ADVEIR;T(0.227)S(0.773)ADVEIR 86.882 0.012143000000000001 6539000.0 47118.0 47691.0 46931.0 44255.0 52935.0 62961.0 70057.0 59183.0 71957.0 54097.0 True False 46446.08867961706 47580.57441962631 43072.514338898894 47509.660330352264 49821.467374214226 60268.30479925945 73684.20866846628 61932.85823816374 63852.44491919788 63447.59437027851 0.7320386082498085 0.7499192820762804 0.6788675719922307 0.7488016023600064 0.7852380829989777 0.949891093546198 1.1613396756770187 0.9761261849696805 1.0063808652311808 1.0 15.953277844547861 -6.786562000993037 2.758664122773656 1.0366442798868567 0.7292657882130049 0.8861708516200039 0.05106652071370375 0.08304882999105978 1.295061554713516 0.019289592091177307 0.017635608233806027 1.6346997605440714e-07 6.786562000993037 -0.3073784916738518 TS(ph)DIFGSPVTATSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSDIFGSPVTATSR 14 0 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2;H3BMV3;H3BMT0;H3BTV5 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 T(0.021)S(0.914)DIFGS(0.064)PVT(0.001)ATSR 111.72 0.00037289 87874000.0 32877.0 27356.0 28970.0 35892.0 36953.0 36935.0 46971.0 38832.0 42814.0 26182.0 True False 38442.42674965104 30071.72289049434 29660.754669336806 33881.08760343401 29712.32491933008 34998.063579648566 42521.566839408966 37812.70114590497 43440.073753869685 30928.589343402033 1.2429414844247308 0.9722953270388813 0.9590076786241888 1.0954617822122505 0.9606750760415325 1.1315764579840002 1.3748304640502478 1.222580853141028 1.4045281299949335 1.0 14.916653412986674 -7.028295384908104 6.318973642929107 1.2679160764242092 1.0400627051385916 0.35557977044807654 0.12871736493068178 0.1790164941166867 24.419919159731815 0.04578742965180041 0.036628716068911514 9.369245419813354e-08 7.028295384908104 -0.22785337128561767 TS(ph)DSDQQAYLVQR ddPTM_PC-9_Lapatinib_30min_R1 1 TSDSDQQAYLVQR 13 0 Q96CV9-3;Q96CV9-2;Q96CV9 Q96CV9-3 OPTN Optineurin 1 T(0.044)S(0.658)DS(0.298)DQQAYLVQR 118.52 0.000242 7500100.0 15897.0 14072.0 15276.0 15011.0 20574.0 21935.0 20321.0 20116.0 20655.0 18432.0 True False 15670.305864847243 14039.4171485811 14020.066247065248 16114.959015228047 19363.87777004029 20996.89118298244 21373.12194858337 21050.662797068446 18328.6163932075 21617.94664090381 0.7248748516751864 0.6494334259303239 0.6485382945916593 0.7454435558989014 0.8957315924446522 0.9712713021158884 0.9886749330828118 0.9737586620386048 0.8478426141790685 1.0 14.399941876180305 -6.2410864311322545 2.287719608070641 0.9561777357644199 0.6722800672663415 0.8903446228499257 0.04454520141358704 0.0923338579278558 0.9498912481480387 0.014908846488202976 0.019356843745975554 5.740022157672882e-07 6.2410864311322545 -0.2838976684980784 TS(ph)DVGGYYYEK ddPTM_PC-9_AZD4547_30min_R2 1 TSDVGGYYYEK 11 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.23)S(0.77)DVGGYYYEK 161.48 0.0011789 13026000.0 32519.0 46767.0 58761.0 60149.0 75540.0 79019.0 69126.0 79187.0 65568.0 74709.0 True False 42859.3655627807 61883.518171469485 57981.790746244675 46282.57734278632 65052.574915313664 74077.92943844125 75278.0800851939 66950.46868623486 69033.79062027505 72093.4606496499 0.5944972703011564 0.858379076463019 0.804258669562511 0.6419802423926375 0.9023366936350498 1.0275263355498385 1.0441734854568874 0.9286621571905355 0.9575596732102537 1.0 16.13758078303519 -6.468761124460587 4.8981851118922695 0.9887680473164019 0.7410677376293785 0.7287839906276818 0.07657540243132192 0.11877249590921382 6.102863379303455 0.02467216062553798 0.027410345245074116 3.3981212848928717e-07 6.468761124460587 -0.2477003096870234 TS(ph)DVGGYYYEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSDVGGYYYEK 11 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.423)S(0.577)DVGGYYYEK 133.15 7.2536e-05 9252600.0 25395.0 30318.0 34901.0 36089.0 46678.0 37923.0 49606.0 38516.0 32359.0 33343.0 True False 29693.871925887008 33327.770675318265 35733.17220277958 34067.050332116654 37531.78098082671 35934.25112037395 44906.960563660985 37504.9958110753 32832.18915778647 39387.82195695721 0.7538845879403107 0.8461440368989853 0.907213712954948 0.8649132813016402 0.9528777961330593 0.9123188167053943 1.1401229703113582 0.9521977592988145 0.8335619368256845 1.0 15.26546202146271 -4.221475537192311 0.5215873397410979 0.9746591410983383 0.46238415430127083 0.4370008660321141 0.07526334577383882 7.34904832025771 0.9920030416352623 0.04478129168278645 2.599234915668894 6.005158336284135e-05 4.221475537192311 -0.5122749867970675 TS(ph)DVGGYYYEK ddPTM_PC-9_Lapatinib_30min_R1 1 TSDVGGYYYEK 11 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.227)S(0.773)DVGGYYYEK 139.19 0.00010879 16877000.0 45529.0 49128.0 53961.0 43317.0 55686.0 49220.0 45493.0 40504.0 55400.0 50121.0 True False 44879.74811100395 49014.247134415324 49524.53487548364 46502.67668127599 52410.65896288832 47114.97533742398 47848.404941041445 42385.9637071217 49160.26861213724 58784.34806796547 0.7634642483253322 0.8337975795486561 0.8424782531946124 0.7910724233517122 0.8915750652247092 0.8014884384351842 0.8139650521550384 0.7210416564986953 0.8362815992328259 1.0 15.843144453477317 -8.557175557171304 22.98952783284969 1.0000000008468173 0.8096358825093202 0.6371994257575007 0.04334388057897087 3538.7890798826147 2372084.709998269 0.04215193077290641 0.010883581697550266 2.772199257254629e-09 8.557175557171304 -0.1903641183374971 TS(ph)EEELNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSEEELNK 8 0 F8WB24;C9JKL0;C9JIA0;C9JPI1;C9JP71;C9JG07;C9JJN9;Q8N3P4-2;Q8N3P4-3;Q8N3P4 F8WB24 VPS8 Vacuolar protein sorting-associated protein 8 homolog 1 T(0.113)S(0.887)EEELNK 90.906 0.0091242 2848200.0 54949.0 76025.0 62955.0 70613.0 77480.0 61780.0 78368.0 47987.0 55217.0 46804.0 True False 64250.780407779675 83572.2595682785 64456.08595816704 66656.78254043481 62298.350194833736 58540.14804252573 70944.41570481348 46727.39209642931 56024.44416469901 55289.194699739855 1.162085661704926 1.511547781119549 1.1657989650276153 1.2056023406097547 1.126772609605885 1.0587990720508933 1.2831515468816783 0.8451451020437664 1.0132982487618438 1.0 15.754709938196138 -6.476250806627499 0.49178937552248525 0.9648873404790167 1.357108713161504 0.42933381553083516 0.12936987562917232 1.0931030269738782 0.5399238106267122 0.11100787403404624 0.1984756273642042 3.340020969048637e-07 6.476250806627499 0.39222137268248736 TS(ph)EEELNK ddPTM_PC-9_Lapatinib_30min_R1 1 TSEEELNK 8 0 F8WB24;C9JKL0;C9JIA0;C9JPI1;C9JP71;C9JG07;C9JJN9;Q8N3P4-2;Q8N3P4-3;Q8N3P4 F8WB24 VPS8 Vacuolar protein sorting-associated protein 8 homolog 1 T(0.345)S(0.655)EEELNK 85.53299999999999 0.013153999999999999 3369600.0 16717.0 38708.0 31329.0 31919.0 34929.0 41845.0 33435.0 36147.0 30106.0 31503.0 True False 16478.612514477656 38618.37400421244 28753.250553437254 34266.4297386626 32874.54489305618 40055.3868954593 35166.10070128856 37826.52158111122 26715.14524976544 36948.25157489112 0.44599167246322446 1.0452016633570906 0.7782032796641741 0.9274168134642939 0.8897456169589552 1.0840942450083266 0.9517663002269463 1.0237702724427953 0.7230422039217742 1.0 15.173218475885282 -4.753484839833555 24.995269890463025 0.9351474323249774 0.4459907814946327 0.6460010325983458 0.10879999694071467 179.08554529469683 562689.385535293 0.026051559504607476 0.2791428914643163 1.764067342711642e-05 4.753484839833555 -0.4891566508303447 TS(ph)FSFQK ddPTM_PC-9_Lapatinib_30min_R1 1 TSFSFQK 7 0 H0Y7F8;Q9BPZ7-4;Q9BPZ7-3;Q9BPZ7-2;Q9BPZ7 H0Y7F8 MAPKAP1 Target of rapamycin complex 2 subunit MAPKAP1 1 T(0.267)S(0.733)FSFQK 78.556 0.028158 13113000.0 164380.0 111930.0 110010.0 124520.0 98832.0 110000.0 92138.0 105350.0 111520.0 90855.0 True False 162035.91105639955 111670.83296195853 100965.40245088052 133677.6161865429 93018.89607118815 105295.55642252415 96908.45480530351 110244.9455990835 98959.44324233847 106559.16569332228 1.5206191790459356 1.047970226074664 0.9475055645748894 1.2544919558704846 0.8729319103238563 0.988141712047232 0.9094333103564872 1.0345890462052687 0.9286807249143086 1.0 16.70129516639914 -4.76233297843716 4.234774789056903 0.9951568020455581 1.5714229502547388 0.7172390631495642 0.09894046214135849 0.11818633623861895 4.2766458866628705 0.024317867081850502 0.21199629391045974 1.7284905979662296e-05 4.76233297843716 0.5762661482091807 TS(ph)FSVGSDDELGPIR ddPTM_PC-9_AZD4547_30min_R2 1 TSFSVGSDDELGPIR 15 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 T(0.157)S(0.842)FS(0.001)VGSDDELGPIR 85.90899999999999 0.024505000000000002 0.0 5021.8 5499.2 6154.9 7716.4 5754.3 6516.6 4988.1 6666.3 6183.4 5963.2 True False 6618.627940071102 7276.708857282808 6073.282004459781 5937.503197191582 4955.414771448101 6109.115971836467 5432.03123676989 5636.17651133452 6510.241900338707 5754.430183056819 1.1501795537564783 1.2645402977879796 1.0554097992780902 1.0318142732313962 0.861147778982302 1.0616369957574556 0.943973784365967 0.9794499771549089 1.1313443196352053 1.0 12.490457361103253 -5.4438926014675495 3.4561329047550635 0.9962393872378902 1.2065604031919372 0.5544347616451288 0.07236147804298364 0.16530786399497072 3.7463445570598455 0.019267137118147964 0.04316422257428314 3.598383101023473e-06 5.4438926014675495 0.21032101595404706 TS(ph)GMPEICQEYS(ph)GT(ph)LRR ddPTM_PC-9_AZD4547_30min_R2 1 TSGMPEICQEYSGTLRR 17 1 Q02413-2;Q02413 Q02413-2 DSG1 Desmoglein-1 3 T(0.462)S(0.54)GMPEICQEY(0.487)S(0.565)GT(0.946)LRR 50.493 0.029595999999999997 24495000.0 18217.0 16129.0 24698.0 25976.0 23945.0 23738.0 20234.0 26437.0 18316.0 25222.0 True False 24009.62706286098 21342.383830214283 24370.48838261346 19987.634525199384 20620.650070786163 22253.659107426283 22034.78680154807 22351.769111823738 19284.146367144887 24338.985456979328 0.9864678667604896 0.8768805860021682 1.0012943401313836 0.8212188860759531 0.8472271823833597 0.9143215581750936 0.9053288946860965 0.91835253985142 0.7923151275648205 1.0 14.570981411746937 -5.757583496700706 24.999917105045284 0.8825634497452279 0.9470808808982604 0.2009758470521732 0.062589251295772 166.64020882880789 1080405.2276091774 0.01644772092410967 0.02716227054559097 1.7474972593400017e-06 5.757583496700706 0.06451743115303243 TS(ph)IETNIR ddPTM_PC-9_AZD4547_30min_R2 1 TSIETNIR 8 0 A0A0C4DG88;P14859-4;P14859-5;P14859-3;P14859;P14859-2;P14859-6;A0A0A0MT46;H0YLC5;Q9UKI9-3;Q9UKI9;Q9UKI9-2 A0A0C4DG88 POU2F1;POU2F3 POU domain protein;POU domain, class 2, transcription factor 1;POU domain, class 2, transcription factor 3 1 T(0.184)S(0.816)IETNIR 108.43 0.0037941000000000003 3944000.0 13628.0 13702.0 15945.0 28180.0 21410.0 21523.0 20411.0 22006.0 16898.0 17294.0 True False 17961.420519990636 18130.90354278605 15733.55888172208 21683.536376659944 18437.591063501004 20177.16340758007 22227.539458653642 18605.47834757322 17791.19378204928 16688.54232388393 1.0762725809961855 1.0864282326706196 0.9427761020928043 1.299306791200535 1.1048053632050243 1.2090428879880883 1.3319041907478364 1.114865396059538 1.0660723649055486 1.0 14.026570326224517 -5.753591377748679 24.99994776545143 1.1724420375443316 1.0402859301006075 0.2349315639173004 0.10234031662714073 247.67279512124267 788956.7685992979 0.02770535312346859 0.04688459356306761 1.7636346478133364e-06 5.753591377748679 -0.13215610744372408 TS(ph)IETNIR ddPTM_PC-9_Lapatinib_30min_R1 1 TSIETNIR 8 0 A0A0C4DG88;P14859-4;P14859-5;P14859-3;P14859;P14859-2;P14859-6;A0A0A0MT46;H0YLC5;Q9UKI9-3;Q9UKI9;Q9UKI9-2 A0A0C4DG88 POU2F1;POU2F3 POU domain protein;POU domain, class 2, transcription factor 1;POU domain, class 2, transcription factor 3 1 T(0.17)S(0.797)IET(0.033)NIR 70.41199999999999 0.03821 2108100.0 22832.0 28083.0 28888.0 25881.0 24506.0 29000.0 22308.0 26823.0 26222.0 17378.0 True False 22506.41149312399 28017.97553891437 26512.940150904764 27784.37507648508 23064.605260649725 27759.73760230183 23462.999086117696 28069.29450217575 23268.602230098626 20381.76414527053 1.1042425637305038 1.3746590010176218 1.3008167478504034 1.3631977525817993 1.1316294848795871 1.3619889526954083 1.1511760669432607 1.3771768872464885 1.1416382833327001 1.0 14.314991309045489 -8.528440413635265 5.967604973557168 1.0000643292381572 1.2722293865703582 0.42150461997910704 0.10066629234344111 0.11054193891937851 23.28723727004169 0.08939653865734051 0.023173315437651255 2.9618263080109725e-09 8.528440413635265 0.272165057332201 TS(ph)IQSELHR ddPTM_PC-9_Lapatinib_30min_R1 1 TSIQSELHR 9 0 A0A0U1RQE4;A0A494C1M0 A0A0U1RQE4 1 T(0.42)S(0.58)IQSELHR 105.65 0.001486 3452400.0 23329.0 25828.0 35548.0 38446.0 25746.0 16047.0 18061.0 18527.0 35286.0 30349.0 True False 22996.324181985357 25768.196852867604 32625.38065924821 41273.447092096336 24231.67089858352 15360.707217384053 18996.110206848283 19387.832056138755 31311.719101947205 35594.784212499435 0.6460588170642705 0.7239318181852853 0.9165775655353322 1.1595363760514887 0.6807646523131428 0.4315437656731179 0.5336767907748019 0.5446818258651092 0.879671552860596 1.0 15.119378234728563 -4.80688793765166 4.902405898018233 0.7470004238659883 0.6431339303999969 0.02147231077482248 0.21703953049657143 1.0613239192755712 52.62627878999865 0.05996961112829127 0.323547655591994 1.559954970905409e-05 4.80688793765166 -0.10386649346599142 TS(ph)LAEDSCLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSLAEDSCLGR 11 0 Q13469-3;Q13469-4;Q13469-2;Q13469;Q13469-5 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 T(0.027)S(0.973)LAEDSCLGR 80.245 0.045318000000000004 0.0 14679.0 18319.0 17297.0 15967.0 19936.0 14069.0 15043.0 13372.0 14815.0 10729.0 True False 17163.864776534585 20137.589253946688 17709.42607923779 15072.420755712445 16029.68391177345 13331.196872940984 13618.018138111365 13020.999168805141 15031.641347773624 12674.082769282728 1.354249067879959 1.588879417984608 1.397294494727371 1.1892316809104637 1.264760867005181 1.0518470737188854 1.07447760804564 1.0273721109320202 1.1860141377808218 1.0 13.629593721879491 -5.990174363719636 1.0967988994232212 1.0722063836701374 1.4912113820129143 0.7684592232980728 0.0866346384935 0.23499363434443712 0.5742203146214985 0.03349063155624417 0.06901201779871666 1.0228822356008568e-06 5.990174363719636 0.4190049983427768 TS(ph)LAEDSCLGR ddPTM_PC-9_Lapatinib_30min_R1 1 TSLAEDSCLGR 11 0 Q13469-3;Q13469-4;Q13469-2;Q13469;Q13469-5 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 T(0.006)S(0.994)LAEDSCLGR 120.03 0.0009062999999999999 1960600.0 19221.0 31186.0 30257.0 21832.0 34014.0 30502.0 30797.0 30350.0 36089.0 33178.0 True False 18946.9050153003 31113.79073306211 27769.386255397563 23437.59810941703 32013.363394096945 29197.50056363484 32391.517969121687 31760.171798122265 32024.276785982354 38912.77309309388 0.4869070875512324 0.7995778316447997 0.7136316445235816 0.6023111756477891 0.8226955020015929 0.7503320437683411 0.83241350832615 0.8161888571174324 0.822975959831193 1.0 15.24795617623381 -4.193549186316154 0.0865937901335962 1.2161533461185765 2.652416400089514e-15 0.6467259445016416 0.07906036315242748 60.39380753668412 0.7026737912964247 2.2630878712371607 9.64035822346243 6.403992486107156e-05 4.193549186316154 -1.2161533461185738 TS(ph)LAGDTSNSSSPASTGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSLAGDTSNSSSPASTGAK 19 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y6T5;H0Y4F5;H0Y314 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 T(0.295)S(0.705)LAGDTSNSSSPASTGAK 225.69 3.6061999999999996e-35 5776500.0 38899.0 41737.0 37797.0 35987.0 52916.0 44687.0 43207.0 39925.0 33453.0 28966.0 True False 45483.83240972946 45880.37352977631 38698.223825920744 33970.76506142818 42547.48966068437 42343.53505303248 39114.12016840908 38877.01105403422 33942.18683814181 34217.30650527018 1.3292639618704063 1.3408528670341069 1.1309547062086962 0.9927948319426012 1.2434494121894477 1.2374888434456608 1.1431092673055574 1.1361797588611 0.9919596340206966 1.0 15.062438578756412 -1.5228787452803376 0.1899028921815602 1.0197151710393417 2.366907577667411 0.47456545560488883 0.09097803488780346 58.399044782785865 0.6823353280403335 0.2061618317309231 23.05023051688341 0.029999999999999995 1.5228787452803376 1.3471924066280694 TS(ph)LAGDTSNSSSPASTGAK ddPTM_PC-9_Lapatinib_30min_R1 1 TSLAGDTSNSSSPASTGAK 19 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y6T5;H0Y4F5;H0Y314 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 T(0.163)S(0.837)LAGDTSNSSSPASTGAK 187.5 5.3872e-11 7067900.0 33337.0 30403.0 33655.0 30671.0 29503.0 22537.0 26479.0 24124.0 29492.0 26414.0 True False 32861.608266742944 30332.60372145476 30888.015812056903 32926.64765545665 27767.691545129725 21573.145046312962 27849.953057257942 25244.889108991825 26170.300395472048 30979.624705557377 1.0607490755318272 0.9791146280740274 0.9970429308175563 1.0628485002127865 0.8963211081168627 0.6963656032425402 0.89897645055274 0.8148868602808862 0.8447584709048269 1.0 14.919032046636557 -6.428607279573786 5.07656981800221 0.8379332055861263 1.0181123721419223 0.5405399546653828 0.07533135579476039 0.1614001327502945 6.651374223392528 0.022673342576118995 0.025579655165514713 3.727286020214967e-07 6.428607279573786 0.18017916655579602 TS(ph)LSALTQLMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSLSALTQLMK 11 0 O00186 O00186 STXBP3 Syntaxin-binding protein 3 1 T(0.207)S(0.792)LS(0.001)ALTQLMK 73.082 0.022567 2487200.0 19610.0 35848.0 30067.0 35977.0 37033.0 26211.0 40140.0 25501.0 28165.0 25439.0 True False 22929.585684845224 39406.75252882146 30783.911309732484 33961.32532900775 29776.649493614874 24836.449018171592 36337.64861156617 24831.62577054292 28576.85984205492 30050.889324986816 0.7630251949242531 1.3113339875787102 1.0243926885763135 1.1301271307391716 0.9908741525614713 0.8264796675258624 1.2092037682675838 0.8263191648673051 0.9509488898318139 1.0 14.875120066185183 -6.504184875237717 22.7838725545702 0.9606517697515616 1.0714603653096741 0.06944988961912912 0.16056048435720907 582.9580299156845 710503.305631552 0.04783734569214503 0.05319768088870653 3.131952196742953e-07 6.504184875237717 0.11080859555811251 TS(ph)LSPAEILEEK ddPTM_PC-9_AZD4547_30min_R2 2 TSLSPAEILEEK 12 0 A0A2R8Y2X6;A1A5D9;A1A5D9-2 A0A2R8Y2X6;A1A5D9-2 CCDC64B Bicaudal D-related protein 2 1 T(0.362)S(0.637)LS(0.001)PAEILEEK;T(0.132)S(0.868)LSPAEILEEK 166.45 0.000252 3183300.0 25971.0 26800.0 26150.0 21009.5 26244.0 29455.0 27670.0 29171.0 26069.0 25517.0 True False 34229.23776964166 35462.57589743587 25803.23391389352 16166.084368539272 22600.47360441477 27613.174193665895 30132.576396107313 24663.29223289368 27446.95411908171 24623.657596770336 1.3900955873481282 1.4401831148792117 1.0479041877709467 0.6565265255580728 0.917835764877557 1.1214083076466945 1.2237246346399624 1.0016096161168413 1.1146578858650829 1.0 14.587757455132794 -5.288749705135033 6.040881619426521 1.004839075922315 1.4166847164002156 0.5615322127912215 0.14315223859614676 0.1286861726645202 16.55892050673831 0.04188796964674335 0.09322117031093949 5.143399932919446e-06 5.288749705135033 0.41184564047790073 TS(ph)LSPAEILEEK ddPTM_PC-9_Lapatinib_30min_R1 1 TSLSPAEILEEK 12 0 A0A2R8Y2X6;A1A5D9;A1A5D9-2 A0A2R8Y2X6;A1A5D9-2 CCDC64B Bicaudal D-related protein 2 1 T(0.12)S(0.877)LS(0.003)PAEILEEK 143.25 8.388e-05 1260800.0 8803.8 11433.0 8538.7 13151.0 13680.0 11479.0 9527.3 10523.0 8992.8 11682.0 True False 8678.256197580813 11406.527590941421 7836.681046335177 14118.168410449944 12875.369295914816 10988.06992885595 10020.57697656307 11011.936996100188 7979.936165617835 13701.218134713452 0.6333930393819185 0.8325192314135781 0.5719696576817601 1.0304316208702717 0.9397244222609475 0.8019775921249322 0.7313639472080883 0.8037195589347131 0.5824253060682132 1.0 13.742016544179444 -3.957479292540767 1.0465936921336487 0.8139913193688082 3.580561201292335e-11 0.11209279036031472 0.14748452045208948 21.658232761534187 5.443277587173987 0.04657595847226401 29.739280545904414 0.00011028608177573177 3.957479292540767 -0.8139913193330026 TS(ph)MGGTQQQFVEGVR ddPTM_PC-9_AZD4547_30min_R2 1 TSMGGTQQQFVEGVR 15 0 A0A2R8Y6G0;A0A2R8Y804;A0A2R8Y543;A0A2R8Y5C3;A0A2R8Y750;A0A2R8Y5Z1;B4DGU4;A0A2R8YCH5;A0A2R8Y5A3;P35222 A0A2R8Y6G0 CTNNB1 Catenin beta-1 1 T(0.422)S(0.578)MGGTQQQFVEGVR 94.023 0.0027414 49597000.0 71258.0 111120.0 88590.0 101670.0 90286.0 91648.0 113940.0 143610.0 96500.0 84518.0 True False 93916.56174152427 147037.36692996547 87415.23871632229 78231.55228584162 77751.34734980176 85917.23607201128 124080.43926897272 121418.3743295009 101600.7929913455 81559.0505452772 1.15151612376099 1.8028332349006224 1.0718030449336098 0.9592013610115736 0.953313541905915 1.0534359522039145 1.5213570834801458 1.488717358990048 1.2457329053253532 1.0 16.315557360132097 -11.837087894308732 1.9005445442125313 0.0002367227317748462 1.2527763122796693 0.07524514516023428 0.26249224604015975 3647194.4304890167 488900.97492174833 15606282.17837414 0.07438556493436792 1.4551645485747087e-12 11.837087894308732 1.2525395895478946 TS(ph)PAIESTPEGTPQPAGGR ddPTM_PC-9_Lapatinib_30min_R1 1 TSPAIESTPEGTPQPAGGR 19 0 Q8NFU5 Q8NFU5 IPMK Inositol polyphosphate multikinase 1 T(0.227)S(0.773)PAIESTPEGTPQPAGGR 110.32 0.0016745000000000002 0.0 6874.0 7304.3 7825.6 7892.9 10289.0 8362.3 7053.4 9022.9 7887.6 7337.3 True False 6775.975499462791 7287.387342124853 7182.209375689572 8473.37019594254 9683.821248952296 8004.663922473399 7418.59053944874 9442.136873715897 6999.215427889781 8605.542528662307 0.7873966663803225 0.8468248594266892 0.834602740241877 0.9846410226572534 1.1253004928740504 0.9301753951958783 0.8620712191869124 1.097215758595947 0.8133380788692445 1.0 13.07105043320156 -5.745892566562757 7.282805515683167 0.9773317210906561 0.8245043721205763 0.36833289911444134 0.09010583232364634 0.16365879193485297 40.99949673321703 0.02447916865482367 0.04079493704050007 1.795177653319539e-06 5.745892566562757 -0.15282734897007988 TS(ph)PAKQQAPPVR ddPTM_PC-9_Lapatinib_30min_R1 1 TSPAKQQAPPVR 12 1 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 1 T(0.346)S(0.654)PAKQQAPPVR 57.034 0.034957 33131000.0 216470.0 33796.0 40662.0 43332.0 29524.0 31348.0 18574.0 17739.0 45172.0 18134.0 True False 213383.09810426406 33717.74743842006 37318.927319859074 46518.77983131452 27787.456366417326 30007.319115757156 19535.670836720004 18563.21869940332 40084.25367775207 21268.437737963854 10.032852470559147 1.5853419914446452 1.7546623677603423 2.18722129027273 1.3065114000741633 1.4108849688660736 0.9185287174078195 0.8728059356361773 1.8846825597444923 1.0 14.376426444325777 -4.761334017057258 7.275403343319959 1.434164420289697 10.19125086320001 0.9756734054498996 0.4073263046932799 0.015139261499584297 5.197234822970363 0.10867364913558857 0.6534269626572343 1.7324710370811913e-05 4.761334017057258 8.757086442910312 TS(ph)PAPWKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSPAPWKR 8 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(0.409)S(0.591)PAPWKR;T(0.009)S(0.991)PAPWKR 95.35799999999999 0.009476799999999999 19613000.0 95947.0 76013.0 84263.0 106829.0 102939.0 107990.0 113594.0 97791.0 91229.0 84438.0 True False 112188.93206036963 83559.06828758388 86272.14948920708 100843.7174742908 82768.84190379445 102326.81429446996 102833.55397065899 95224.08986812898 92563.05153668828 99745.94098916001 1.1247468413031652 0.8377189834387823 0.8649188992921806 1.0110057258896388 0.8297965920516951 1.025874469474306 1.0309547732056037 0.9546663144766718 0.9279881528888244 1.0 16.605970513777095 TS(ph)PASLDFPESQK ddPTM_PC-9_Lapatinib_30min_R1 1 TSPASLDFPESQK 13 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 T(0.174)S(0.826)PASLDFPESQK 85.42 0.0081003 2893300.0 20776.0 19666.0 19810.0 16867.0 16694.0 21075.0 19795.0 17221.0 20246.0 16160.0 True False 20479.73043014823 19620.46458527545 18181.298268811395 18107.455446662563 15712.09174166681 20173.6713782245 20819.888242321133 18021.150528351358 17965.682280168436 18953.234468153518 1.0805401296839139 1.0352040237904014 0.9592715322211003 0.955375478369558 0.8289926327913745 1.0643920124621282 1.0984873467008542 0.9508219063417218 0.9478953215270759 1.0 14.21015645237715 -5.037033768628506 3.2748998116568653 0.9756709581509748 1.0769399659843375 0.19864462038604103 0.06874572806511813 0.4371492736877303 9.144555980216577 0.019363194428965644 0.08099671066335937 9.182611941794002e-06 5.037033768628506 0.10126900783336268 TS(ph)PDPSPVSAAPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSPDPSPVSAAPSK 14 0 Q13469-3;Q13469-4;Q13469-2;Q13469;Q13469-5 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 T(0.225)S(0.775)PDPSPVSAAPSK;T(0.033)S(0.966)PDPS(0.001)PVSAAPSK 206.45 8.320600000000001e-11 83749000.0 209710.0 280850.0 364850.0 458990.0 508700.0 445780.0 463710.0 553320.0 435480.0 334720.0 True False 245209.76103869962 308730.93192701193 373549.40770132956 433274.2783656583 409023.886733504 422402.5120491597 419784.0318303268 538795.9362910019 441848.0711527812 395402.0863579389 0.6201529266001969 0.7808024858208066 0.9447330213709921 1.0957814673072703 1.0344505020219694 1.068285997021216 1.0616636743042274 1.3626532455958142 1.11746519909052 1.0 18.592960957973105 -4.424835655063999 0.6010212381594904 1.1487806848365532 6.73311696902362e-09 0.7579348901866876 0.09319339696041422 2.526642814968414 0.5086935972231698 0.04659481291145795 2.2080145124961255 3.7597965491578714e-05 4.424835655063999 -1.1487806781034362 TS(ph)PDSLR ddPTM_PC-9_AZD4547_30min_R2 1 TSPDSLR 7 0 Q9BRL6-2;Q9BRL6 Q9BRL6-2 SRSF8 Serine/arginine-rich splicing factor 8 1 T(0.224)S(0.776)PDSLR 112.41 0.009174 10244000.0 67160.0 71136.0 85221.0 90128.0 75625.0 89111.0 75727.0 103730.0 89346.0 70086.0 True False 88515.48298521963 94129.32085970153 84090.91385758785 69350.38206371925 65125.77413252048 83538.87508306779 82466.55629736229 87700.91197826811 94068.64715652599 67632.31047251797 1.3087750864461065 1.3917803517588014 1.243354149371516 1.0254031184089063 0.9629387740491875 1.2351917966341452 1.2193366709077924 1.2967309761494088 1.390883240559263 1.0 16.04542501987403 -5.518063370138702 24.67454542394121 1.168246506956875 1.342100138987794 0.25183412751056344 0.12946363167052166 259.82640538727526 1331378.3323733292 0.038070771637205965 0.0683394901180005 3.0334485258434117e-06 5.518063370138702 0.17385363203091897 TS(ph)PDSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSPDSLR 7 0 Q9BRL6-2;Q9BRL6 Q9BRL6-2 SRSF8 Serine/arginine-rich splicing factor 8 1 T(0.125)S(0.874)PDS(0.001)LR;T(0.225)S(0.775)PDSLR 120.87 0.0058682 10606600.0 82814.0 118564.0 91019.0 96456.0 117956.0 73919.0 107030.0 71202.0 83254.0 75523.0 True False 96832.77454894283 130334.25035782196 93189.23815147983 91051.88303457115 94843.36855423095 70042.5575130375 96891.34356990375 69333.0229447549 84471.43224890599 89214.72206026081 1.0853900826316125 1.460905188605381 1.0445500025044565 1.020592576335881 1.0630910052061613 0.7851008880095672 1.0860465776540524 0.7771477772236218 0.9468328802487225 1.0 16.4449941803989 -5.463959879647143 5.067722624273923 0.9526759864035526 1.2742470909043573 0.48614439877236004 0.12921342359273508 0.15884926471252098 8.407992664152694 0.03291667600894116 0.06895107541629444 3.435896874299903e-06 5.463959879647143 0.3215711045008047 TS(ph)PDSLR ddPTM_PC-9_Lapatinib_30min_R1 1 TSPDSLR 7 0 Q9BRL6-2;Q9BRL6 Q9BRL6-2 SRSF8 Serine/arginine-rich splicing factor 8 1 T(0.224)S(0.776)PDSLR 112.41 0.009174 11805000.0 43979.0 71262.0 75636.0 69854.0 82469.0 77902.0 78404.0 75603.0 75441.0 66534.0 True False 43351.85139523913 71096.99721732426 69417.50004340312 74991.29618611284 77618.33556029234 74570.31305843165 82463.37548628163 79115.79138232069 66944.04015105132 78034.31324901784 0.5555485733166847 0.9110991595510595 0.889576612558666 0.9610041155460121 0.9946692977562568 0.9556092692258071 1.0567578806406621 1.013859007509321 0.857879532269657 1.0 16.251821024918534 -4.429024311559597 1.4879585641540523 0.974816170741386 2.9988970866251715e-24 0.8294859330247657 0.0554199354155747 1.12117276699706 1.1627489578819985 0.015667159321106634 2.0825464671454377 3.723708605608303e-05 4.429024311559597 -0.974816170741386 TS(ph)PDTLR ddPTM_PC-9_AZD4547_30min_R2 2 TSPDTLR 7 0 J3QL05;J3KP15;Q01130-2;Q01130 J3QL05 SRSF2 Serine/arginine-rich splicing factor 2 1 T(0.016)S(0.969)PDT(0.016)LR;T(0.23)S(0.769)PDTLR 148.99 0.0011167999999999998 859510000.0 1814238.0 1909620.0 2316462.0 2398006.0 2165922.0 2625230.0 2387905.0 2572230.0 2526691.0 2266768.0 True False 2391127.945505334 2526867.320345577 2285744.2003306164 1845182.7655233755 1865221.116835135 2461073.9530958273 2600423.919015055 2174750.957465154 2660246.727918086 2187409.142270481 1.0931324640178641 1.1551873271055024 1.044955036604659 0.8435471580813261 0.8527079277446367 1.125109109922293 1.1888145974903779 0.994213160875707 1.216163303202075 1.0 21.060791662740876 TS(ph)PDTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSPDTLR 7 0 J3QL05;J3KP15;Q01130-2;Q01130 J3QL05 SRSF2 Serine/arginine-rich splicing factor 2 1 T(0.224)S(0.774)PDT(0.002)LR 115.49 0.0082036 365030000.0 1683300.0 2345500.0 1677700.0 1828800.0 2073100.0 1454900.0 1722300.0 1258700.0 1310000.0 1363900.0 True False 1968249.4433095322 2578345.739130514 1717702.7307126853 1726338.265049599 1666890.9368728702 1378602.4827949286 1559151.2756278105 1225660.4587028876 1329156.2717234846 1611164.2733735444 1.2216317577526115 1.6002997222200266 1.0661251363996949 1.0714849463704263 1.034587822247723 0.8556560653547356 0.9677171356109913 0.7607296654713751 0.8249663263327109 1.0 20.619672167216542 -5.725294215305566 0.9924019363430155 0.87418299252246 1.4352627819001542 0.6717575482219895 0.12984886276918658 0.36373102762783355 0.6625261577849576 0.04921340338719698 0.1579543486529187 1.8823734326821234e-06 5.725294215305566 0.5610797893776942 TS(ph)PDTLR ddPTM_PC-9_Lapatinib_30min_R1 3 TSPDTLR 7 0 J3QL05;J3KP15;Q01130-2;Q01130 J3QL05 SRSF2 Serine/arginine-rich splicing factor 2 1 T(0.222)S(0.777)PDT(0.001)LR;T(0.236)S(0.764)PDTLR;T(0.205)S(0.792)PDT(0.003)LR 148.99 0.0011167999999999998 1051750000.0 1077656.0 1654636.0 1745510.0 1463834.0 2154630.0 1639560.0 1973110.0 1992500.0 1610368.0 1413722.0 True False 1062288.4278220923 1650804.792002533 1602000.9056634505 1571489.2355670766 2027898.8995655647 1569439.8408010323 2075267.981298625 2085078.823978864 1428991.3979131817 1658081.964033845 0.6406730492609162 0.9956110902903691 0.9661771495095703 0.9477753631333746 1.2230389953895975 0.9465393598413188 1.2516075961949635 1.2575245791264773 0.8618339918713529 1.0 20.661083894723824 -4.252951971899808 0.8700525056941311 1.092397312472405 6.457492815129824e-17 0.4511261054797451 0.13529616517100954 4.6345970351230505 1.4378896004663224 0.0462868531958723 6.012169793423539 5.585319586936853e-05 4.252951971899808 -1.092397312472405 TS(ph)PDTLRR ddPTM_PC-9_AZD4547_30min_R2 1 TSPDTLRR 8 1 J3QL05;J3KP15;Q01130-2;Q01130 J3QL05 SRSF2 Serine/arginine-rich splicing factor 2 1 T(0.126)S(0.871)PDT(0.003)LRR 76.943 0.011113 465060000.0 43245.0 43344.0 71548.0 75321.0 66176.0 67094.0 56333.0 61751.0 60060.0 54838.0 True False 56996.01044812115 57354.10036188282 70599.22677136725 57956.90714784959 56988.60468090817 62898.60157358072 61346.5278685187 52208.80184681426 63234.64898507987 52918.138311388146 1.077060007529695 1.08382687282746 1.334121513420174 1.0952181803299963 1.0769200599153361 1.1886019346233265 1.1592722235906159 0.9865955892023278 1.194952260281454 1.0 15.691474687270116 -9.83442839022047 0.3485732412405614 0.9637193466142262 1.1496193580177088 0.15954818115396074 0.08960485876386183 12.91978530418188 1.8019097241527973 0.6932811802148487 0.0792263236347246 1.4641029300829437e-10 9.83442839022047 0.18590001140348256 TS(ph)PENVQDR ddPTM_PC-9_Lapatinib_30min_R1 2 TSPENVQDR 9 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 T(0.171)S(0.829)PENVQDR;T(0.154)S(0.846)PENVQDR 106.16 0.0025881 192290000.0 61184.0 66765.0 58003.0 56283.0 71484.0 61279.0 58746.0 60611.0 71723.0 48752.0 True False 60311.50494022854 66610.40974452949 53234.21723805482 60422.23957458398 67279.45166295125 58658.24001832594 61787.58043361443 63427.20833133406 63644.800463327156 57178.71824204332 1.05478938308697 1.1649510830683694 0.9310145255916542 1.0567260238120504 1.1766519735218706 1.0258753924846593 1.0806045034458682 1.1092799957991408 1.1130854699105401 1.0 15.803190659424478 -6.028550123975717 24.98205177052979 1.089346810596023 1.0504130275793084 0.04740048108366279 0.06932897635668155 2149.7799317695653 1881105.2306669664 0.02025507293439934 0.026198053624553398 9.363751421833787e-07 6.028550123975717 -0.03893378301671446 TS(ph)PHWK ddPTM_PC-9_Lapatinib_30min_R1 1 TSPHWK 6 0 Q9BRD0;H7C462 Q9BRD0 BUD13 BUD13 homolog 1 T(0.065)S(0.935)PHWK 89.296 0.02162 6569700.0 47792.0 67629.0 73769.0 64527.0 67969.0 69868.0 65484.0 72259.0 72179.0 59061.0 True False 47110.47731602062 67472.40920561325 67703.99757657485 69272.5308357618 63971.19705219545 66879.90851026283 68874.44110432715 75616.4169344487 64049.44094143417 69269.61515616416 0.6801030612024175 0.9740549164810687 0.9773982058935983 1.000042091753954 0.9235102130707129 0.9655013725640906 0.9942951314086832 1.091624614399489 0.9246397687794076 1.0 16.079935038169182 -4.761033289225939 5.898661857817952 0.9853126613347647 0.6680725491596545 0.8074537412868952 0.044465378603892824 0.057579757032515 7.410987661171163 0.011167243349521305 0.07404343526289026 1.7336711045596918e-05 4.761033289225939 -0.31724011217511017 TS(ph)PIMSPR ddPTM_PC-9_Lapatinib_30min_R1 1 TSPIMSPR 8 0 Q13469-3;Q13469-4;Q13469-2;Q13469 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 T(0.226)S(0.774)PIMSPR 86.882 0.012143000000000001 4398000.0 92594.0 78318.0 87323.0 68382.0 67431.0 58062.0 48077.0 54678.0 63781.0 50394.0 True False 91273.59258034002 78136.65948284372 80143.64001652777 73411.04039566494 63464.84115444676 55578.823609132705 50566.191817432344 57218.539491852716 56597.312136294735 59104.53575421587 1.54427391088728 1.3220078372288089 1.3559642926526363 1.2420542596077933 1.0737727713210212 0.9403478582465361 0.8555382623714375 0.968090498668224 0.9575798441536308 1.0 15.850981228379014 -6.1181360740732655 1.175442698626164 0.9301171308501264 1.438308700014473 0.9192289704243848 0.06090459060857169 0.12453681043950786 0.3522120858808868 0.024456298889509162 0.04185439921846613 7.618402712077784e-07 6.1181360740732655 0.5081915691643466 TS(ph)PINEDIR ddPTM_PC-9_AZD4547_30min_R2 3 TSPINEDIR 9 0 D6RA28;A0A590UJ84;B1AKN3;Q9P2R6-2;Q9P2R6 D6RA28 RERE Arginine-glutamic acid dipeptide repeats protein 1 T(0.228)S(0.772)PINEDIR;T(0.204)S(0.796)PINEDIR;T(0.224)S(0.776)PINEDIR 156.01 8.4438e-05 32453900.0 136208.0 176082.0 175884.0 155647.0 146508.0 190267.0 179189.0 219712.0 181225.0 158732.0 True False 179519.31069759902 232997.06302881712 173551.66323943573 119764.98887217857 126167.89311216294 178369.57441202618 195136.47386491066 185760.5588794877 190804.18352182992 153174.84099426089 1.171989535176506 1.5211183606682968 1.1330298246951556 0.7818842056226838 0.8236854844647116 1.1644834964686483 1.2739459861572304 1.2127354445006262 1.2456626837887752 1.0 17.2248198281388 -5.500122366012931 23.76357325253173 1.0729598864033647 1.3416841506819461 0.27383518049663824 0.17644100119671224 569.3253072519319 594520.9527498172 0.051467083636914844 0.1057264434368528 3.1613867881532137e-06 5.500122366012931 0.2687242642785814 TS(ph)PINEDIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSPINEDIR 9 0 D6RA28;A0A590UJ84;B1AKN3;Q9P2R6-2;Q9P2R6 D6RA28 RERE Arginine-glutamic acid dipeptide repeats protein 1 T(0.233)S(0.767)PINEDIR 72.096 0.033208 12847000.0 56036.0 78520.0 62229.0 63886.0 72411.0 56635.0 57839.0 42718.0 43603.0 36901.0 True False 65521.788038551094 86314.94667939817 63712.775364796704 60306.67454120659 58222.5843567128 53664.960899780606 52360.07120190274 41596.69776346232 44240.611386228324 43590.85919184475 1.5031084326690518 1.980115746274313 1.461608615797059 1.3834706555288347 1.3356603984443933 1.231105830320972 1.2011708916189152 0.9542527615799894 1.0149056982686209 1.0 15.411738019570736 -6.232404936314731 0.5436764947366728 0.9712621528906881 1.8194897536553374 0.7805032878452889 0.13603369834979906 0.5066876721209284 0.2975809405798434 0.10308623921542394 0.22510327029815222 5.855919038071554e-07 6.232404936314731 0.8482276007646493 TS(ph)PINEDIR ddPTM_PC-9_Lapatinib_30min_R1 3 TSPINEDIR 9 0 D6RA28;A0A590UJ84;B1AKN3;Q9P2R6-2;Q9P2R6 D6RA28 RERE Arginine-glutamic acid dipeptide repeats protein 1 T(0.216)S(0.784)PINEDIR;T(0.209)S(0.791)PINEDIR;T(0.181)S(0.819)PINEDIR 183.99 0.004171500000000001 28982000.0 135703.0 197278.0 166553.0 151159.0 194831.0 196064.0 200636.0 190199.0 156745.0 167533.0 True False 133767.85033511763 196821.2149117244 152859.65525317256 162275.73711164197 183371.4236324836 187678.79976750712 211023.95036051236 199036.33989558675 139090.72750197587 196490.85582630945 0.6807840994563299 1.0016812949591252 0.7779479335582657 0.8258691552297357 0.9332313346661641 0.9551528440255161 1.0739632105172854 1.0129547202518545 0.707873793500736 1.0 17.58410264920569 -6.337333688779972 3.909892349842579 0.9571078584386573 0.8309573228278078 0.21640380960123806 0.11635511824059623 0.3882938194168799 11.407981506884115 0.03676392008151956 0.042700221573635566 4.599030727340656e-07 6.337333688779972 -0.12615053561084955 TS(ph)PITR ddPTM_PC-9_AZD4547_30min_R2 2 TSPITR 6 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(0.225)S(0.775)PITR;T(0.23)S(0.77)PITR 116.9 0.021828999999999998 200883000.0 643360.0 477340.0 616070.0 820530.0 684060.0 705890.0 594340.0 622750.0 582320.0 688800.0 True False 847935.0972806845 631630.8201075388 607900.5092670134 631369.4855621291 589090.0767351007 661750.5867108057 647235.1086108588 526518.2968713648 613100.246370159 664685.3216544022 1.275694030929062 0.9502704505876696 0.9145688786295877 0.9498772802604547 0.8862691224606181 0.9955847754599244 0.9737466550335281 0.7921316745205994 0.9223917339473543 1.0 19.342311969433332 -4.760885391981827 4.75829787920523 0.9253897463806747 1.3015369841820879 0.7647672884709033 0.057313708323599624 0.0887836939173658 4.846471711440577 0.01447424718984103 0.11338510149890228 1.7342615998413063e-05 4.760885391981827 0.3761472378014131 TS(ph)PITR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TSPITR 6 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(0.222)S(0.778)PITR;T(0.179)S(0.821)PITR;T(0.223)S(0.777)PITR;T(0.017)S(0.983)PITR;T(0.18)S(0.82)PITR 116.9 0.021828999999999998 380408700.0 1048493.0 1311140.0 1158907.0 1204940.0 1436059.0 1053690.0 1157013.0 1052488.0 994301.0 961784.0 True False 1225982.1562192964 1441301.3141776097 1186539.7380592725 1137431.1182681867 1154673.547785786 998432.6414847673 1047412.3525912823 1024861.3052032166 1008840.7710923172 1136147.825722044 1.0790692271405447 1.2685860779266418 1.0443533061423618 1.0011295119500203 1.0163057320925368 0.8787876180199032 0.921897951022026 0.9020492597887931 0.8879485118507173 1.0 20.115719127372095 -5.814075983695974 1.1458705472311572 0.9173231594037121 1.1793389656361735 0.6802560081114504 0.06285683769418986 0.27932785527183684 0.7233329255713561 0.022344975652430963 0.056717957079282594 1.5343485113471058e-06 5.814075983695974 0.26201580623246135 TS(ph)PITR ddPTM_PC-9_Lapatinib_30min_R1 4 TSPITR 6 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(0.222)S(0.778)PITR;T(0.018)S(0.982)PITR;T(0.23)S(0.77)PITR;T(0.209)S(0.791)PITR 126.28 0.012286 391536000.0 832104.0 1067200.0 1176300.0 1052220.0 1258510.0 1062520.0 1101530.0 1158210.0 1282930.0 997270.0 True False 820238.0443708169 1064728.9639685703 1079589.15464931 1129603.7689030198 1184486.9161258584 1017078.496455094 1158561.8335723164 1212024.664853482 1138432.913548182 1169646.7907212563 0.7012698627292617 0.9102995642915508 0.9230044174135572 0.965764859839829 1.0126876981344524 0.8695603702959918 0.9905228165999547 1.0362313430587824 0.9733134161349458 1.0 20.157641500664973 -4.145203959045968 1.1100619226907071 0.9765656546128351 1.7067818174135316e-13 0.7796616899547533 0.043420285256761365 2.7599911130408965 1.0383029295878918 0.01369565630157462 4.446498609931543 7.158071645548226e-05 4.145203959045968 -0.9765656546126644 TS(ph)PKPAVVETVTTAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSPKPAVVETVTTAK 15 1 H0YI94;H0YIP0;P56192 H0YI94 MARS Methionine--tRNA ligase, cytoplasmic 1 T(0.456)S(0.544)PKPAVVETVTTAK 82.48200000000001 0.0036571 12871000.0 120910.0 196580.0 105630.0 122560.0 138830.0 77778.0 117000.0 85816.0 73475.0 84621.0 True False 141377.67491864547 216095.1632480398 108148.61980400553 115693.36054488122 111627.2580994937 73699.18475965633 105916.91299335449 83563.42092956793 74549.4328739564 99962.11744053273 1.4143125269705372 2.1617705665007985 1.0818960479537953 1.157372047603003 1.1166956138749315 0.7372711447764182 1.0595705223667782 0.8359508888882796 0.7457768480975376 1.0 16.609093841084125 -5.389081472788634 5.614114094035151 0.9586548082226947 1.7818240099928815 0.6990436509339342 0.21659437945587312 0.11182406348242047 4.587559396400776 0.05587165749859726 0.1187732390469255 4.082427936053266e-06 5.389081472788634 0.8231692017701868 TS(ph)PKPAVVETVTTAK ddPTM_PC-9_Lapatinib_30min_R1 1 TSPKPAVVETVTTAK 15 1 H0YI94;H0YIP0;P56192 H0YI94 MARS Methionine--tRNA ligase, cytoplasmic 1 T(0.263)S(0.737)PKPAVVETVTTAK 58.023999999999994 0.028462 6009400.0 22617.0 46675.0 43499.0 48683.0 54127.0 54325.0 47805.0 57979.0 50821.0 36475.0 True False 22294.47743255016 46566.92690520347 39922.68013099578 52263.310221727224 50943.35627777638 52001.64638776022 50280.10898833858 60672.91600274563 45097.0038111449 42779.65515011756 0.5211467309476171 1.088529740171959 0.9332165018839819 1.2216861037876692 1.1908313916746565 1.2155695553244148 1.1753275899934505 1.418265663662763 1.0541694095685334 1.0 15.38463723243061 -4.526841946285421 1.1629768972693706 1.1913747047676089 9.495361721219948e-26 0.6627350941351748 0.13181966300603548 1.5098653245593538 1.172247876014337 0.03818768183726795 2.5195948044019136 2.9727477132953314e-05 4.526841946285421 -1.1913747047676089 TS(ph)PLKDNPSPEPQLDDIKR ddPTM_PC-9_AZD4547_30min_R2 1 TSPLKDNPSPEPQLDDIKR 19 2 Q96JC9-2;Q96JC9 Q96JC9-2 EAF1 ELL-associated factor 1 1 T(0.182)S(0.666)PLKDNPS(0.152)PEPQLDDIKR 49.395 0.021106 19419000.0 32826.0 25723.0 26959.0 38599.0 36713.0 33225.0 34174.0 27567.0 27516.0 33585.0 True False 43263.98517678401 34037.45670931877 26601.50604530231 29700.59689860528 31616.033662508744 31147.435497693074 37215.41979618981 23307.15357664051 28970.43958497264 32409.1993724784 1.334929156365504 1.050240591201493 0.8208010861228515 0.9164248877998127 0.9755265256369398 0.9610677246209048 1.1482980300893457 0.7191524020316508 0.8938955650220127 1.0 14.984115760722881 -4.830244201369334 3.1897267535223155 0.9294165525753236 1.3720329153310966 0.5673715089277036 0.1070349991035588 0.22380333150951903 3.648733838197515 0.027780948088012358 0.23378642446539508 1.478276927540903e-05 4.830244201369334 0.442616362755773 TS(ph)PLVSQNNEQGSTLR ddPTM_PC-9_Lapatinib_30min_R1 2 TSPLVSQNNEQGSTLR 16 0 A0A1W2PNZ9;Q15652-3;Q15652;H7BXU7 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 T(0.238)S(0.762)PLVSQNNEQGSTLR;T(0.24)S(0.76)PLVSQNNEQGSTLR 120.32 9.399899999999999e-05 17635100.0 23802.3 38487.0 37993.0 31742.0 37699.0 42174.0 44283.0 37513.0 37370.0 34291.0 True False 23462.874837192765 38397.885716134224 34869.36219722116 34076.41256820792 35481.618939085696 40370.31633239575 46575.757061616925 39255.9909279394 33160.99707645432 40218.15366011461 0.5833901534983071 0.9547401414952176 0.8670055441108432 0.8472893324787901 0.8822289366872091 1.0037834325654795 1.1580779529371414 0.9760764071790443 0.8245280814405198 1.0 15.2955592312937 -6.618469149420424 3.1232861618737124 1.001516806909085 0.8291168776181361 0.3444776610658028 0.11601846365613834 0.3173136340425443 6.205794549229318 0.04137180523032433 0.041588627603239677 2.407303518393028e-07 6.618469149420424 -0.17239992929094883 TS(ph)PPLLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSPPLLDR 8 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(0.076)S(0.924)PPLLDR;T(0.223)S(0.777)PPLLDR;T(0.203)S(0.797)PPLLDR 109.44 0.003778 88096800.0 154028.0 189279.0 195298.0 195605.0 211479.0 157197.0 189210.0 154612.0 169460.0 143346.0 True False 180101.89820832945 208069.3682186682 199954.64499178977 184645.88600996643 170041.20806470368 148953.31259049714 171286.65903822734 150553.5988249549 171938.0319131768 169333.4950736884 1.0635928711561466 1.2287549378705214 1.1808333897837286 1.0904274191565855 1.0041794034352585 0.8796447065932085 1.011534421844237 0.8890952068250816 1.015381108376432 1.0 17.369507848716424 -6.184408364242945 2.37577007542845 0.955057494946992 1.1630008815244406 0.6875731981517441 0.0589459235515815 0.15411914971040133 1.7059238612850345 0.018252883859619012 0.024555799236399934 6.540209132895698e-07 6.184408364242945 0.2079433865774486 TS(ph)PPLLDR ddPTM_PC-9_Lapatinib_30min_R1 3 TSPPLLDR 8 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 T(0.202)S(0.798)PPLLDR;T(0.024)S(0.976)PPLLDR;T(0.163)S(0.837)PPLLDR 113.66 0.0037104 11475000.0 79038.0 112624.0 111663.0 89543.0 107363.0 109816.0 92433.0 93550.0 107622.0 89817.0 True False 77910.90362620597 112363.22604759785 102482.49917164467 96128.2909266917 101048.11942377935 105119.4256735991 97218.72846185749 97896.67452106565 95500.47705009807 105341.74877637056 0.7396013881600031 1.0666542691078078 0.9728573937879484 0.9125374511368891 0.9592409524004948 0.9978895062465364 0.9228888792063118 0.9293245618020827 0.9065776689623364 1.0 16.68471778939309 -4.74285809046538 24.961521137758943 0.9593328298173713 0.7396006641081725 0.670383452492636 0.04694980273268986 765.5864089872637 1028410.107777361 0.011893884215621977 0.40343669389545234 1.807764732509402e-05 4.74285809046538 -0.21973216570919885 TS(ph)PQVLGSILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSPQVLGSILK 11 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 T(0.147)S(0.853)PQVLGSILK 156.52 0.0007641 82448000.0 135680.0 122540.0 113470.0 135900.0 144280.0 116340.0 123670.0 129480.0 120930.0 88712.0 True False 158647.94419784792 134704.9613613529 116175.55513737121 128285.9635937445 116009.36972264608 110238.92559513498 111955.08230673595 126081.28719539983 122698.37247291664 104794.78335619421 1.5138916186181566 1.285416669105512 1.1086005564083672 1.2241636414066959 1.107014738780783 1.0519505080747797 1.0683268643841182 1.2031256056597155 1.1708442781533188 1.0 16.677207376298178 -4.236451875736527 1.0313084507162205 1.1143293728999748 2.320129545622449 0.7830635430977474 0.06527570978022351 2.2671137679170714 0.8960922705442385 0.0211572259605332 3.9494889035834886 5.8016045666398283e-05 4.236451875736527 1.2058001727224743 TS(ph)PQVLGSILK ddPTM_PC-9_Lapatinib_30min_R1 1 TSPQVLGSILK 11 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 T(0.148)S(0.852)PQVLGSILK 151.16 0.00035525 90320000.0 117700.0 101750.0 106370.0 109730.0 111430.0 101030.0 96426.0 89946.0 97666.0 83251.0 True False 116021.57641646343 101514.40412650126 97624.66920007409 117799.91024854929 104875.90647980911 96709.18241243294 101418.46646395832 94125.2195240167 86665.82661142586 97640.8244250154 1.18824863574932 1.039671722604725 0.9998345443615778 1.206461651079312 1.0740989447538924 0.9904584786325937 1.0386891657376778 0.9639945184639592 0.887598267648611 1.0 16.575196856037422 -7.178398879391314 1.1518032107333966 0.9475588105644883 1.0987635959738535 0.46691938740121 0.06751590594561332 0.47110498871972667 1.2369377269226471 0.04487802395059834 0.027459138333239454 6.63133732963231e-08 7.178398879391314 0.15120478540936522 TS(ph)PSGGTWSSVVSGAK ddPTM_PC-9_Lapatinib_30min_R1 1 TSPSGGTWSSVVSGAK 16 0 F8WB06;F8VRK6 F8WB06 ATXN2 1 T(0.151)S(0.847)PS(0.002)GGTWSSVVSGAK 150.39 3.0859000000000004e-05 5050900.0 37360.0 25764.0 34245.0 29817.0 29062.0 27198.0 21453.0 25786.0 33728.0 20909.0 True False 36827.2395490151 25704.345040935437 31429.508289522742 32009.841646596153 27352.630298090367 26034.804941634662 22563.73136966481 26984.111696421103 29929.197468414528 24523.092790508785 1.5017371529609191 1.0481689752804686 1.2816290570693007 1.3052938273342496 1.1153825715114003 1.0616444330264476 0.9201013739342735 1.1003551602131036 1.2204495462333396 1.0 14.581853319106388 -6.4086471852173315 3.8071284858485344 1.0600165831583666 1.2666845546216172 0.41679473532651046 0.12479017600758643 0.2623584204272621 6.745727733188555 0.04000698566004003 0.045317276669202745 3.9025889882047526e-07 6.4086471852173315 0.20666797146325067 TS(ph)PSGGTWSSVVSGVPR ddPTM_PC-9_Lapatinib_30min_R1 1 TSPSGGTWSSVVSGVPR 17 0 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4 Q99700 ATXN2 Ataxin-2 1 T(0.229)S(0.767)PS(0.003)GGT(0.001)WSSVVSGVPR 91.789 0.0021564 37414000.0 75090.0 92286.0 112030.0 93258.0 84458.0 92661.0 94732.0 92576.0 88226.0 69184.0 True False 74019.20283018037 92072.31743703476 102819.32584830566 100116.50441956817 79490.3464908167 88698.1050333409 99636.75943276401 96877.41892530349 78289.05881903287 81142.36221811463 0.9122140495640628 1.1347009739442866 1.2671473079859603 1.2338376858002988 0.9796405270670178 1.0931171167400335 1.2279252995486567 1.1939191351724794 0.9648358351780302 1.0 16.308167682472643 -8.271068788528538 24.689046477197078 0.982417882380631 1.1354625068801354 0.23143054228834947 0.1074790441514079 969.4701246708017 2485610.7071590484 0.10300561293275208 0.027991899380639784 5.357117986296446e-09 8.271068788528538 0.1530446244995044 TS(ph)PSVTPTPAR ddPTM_PC-9_AZD4547_30min_R2 1 TSPSVTPTPAR 11 0 Q8WXE0-2;Q8WXE0 Q8WXE0-2 CASKIN2 Caskin-2 1 T(0.154)S(0.845)PS(0.002)VTPTPAR 89.9 0.009030400000000001 3476300.0 21145.0 22624.0 27781.0 35094.0 33073.0 29124.0 22372.0 31973.0 22756.0 23983.0 True False 27868.670156677555 29936.765563566765 27412.60578821707 27003.620496895106 28481.38483153521 27302.871675991355 24363.064659693267 27032.307516448174 23958.835702705237 23143.36246985706 1.2041755035801278 1.2935356996010297 1.1844694488072105 1.16679763072742 1.2306502509577262 1.1797279548964341 1.052702030287293 1.1680371662352975 1.0352357283394011 1.0 14.498310866560612 -7.627669288146171 0.40723591616404 0.9919753500075198 1.251119374965999 0.7166594038949179 0.04696166081047239 0.5937586101153611 0.25657033400774787 0.053631164702144477 0.04925161950689234 2.356843318505262e-08 7.627669288146171 0.2591440249584792 TS(ph)PTPGDFPK ddPTM_PC-9_AZD4547_30min_R2 1 TSPTPGDFPK 10 0 Q9UPU7;C9JW56;Q9UPU7-2 Q9UPU7 TBC1D2B TBC1 domain family member 2B 1 T(0.425)S(0.567)PT(0.009)PGDFPK 91.93700000000001 0.007752299999999999 6534100.0 116650.0 110690.0 123660.0 134170.0 139050.0 150980.0 129440.0 145210.0 141230.0 117990.0 True False 153742.27352927133 146468.3778390736 122020.18760199126 103239.17940583629 119745.30767771181 141539.1967326318 140959.90924149365 122771.13109384307 148695.1294732405 113859.20601336105 1.3502840825293487 1.2863990797712568 1.0716760802606733 0.9067266760469195 1.0516963174998784 1.2431071820053143 1.2380194292322082 1.0782714493849204 1.3059561424992858 1.0 16.796891418813196 -1.5228790257067732 0.012019708866289789 1.1577405554148553e-12 2.484715241821853 0.08473023174525496 0.13596516211177367 32963.68207085977 30.72860134714525 2656.2921449595733 3788.795007226497 0.029999980628834338 1.5228790257067732 2.4847152418206955 TS(ph)PTPPESATTVK ddPTM_PC-9_AZD4547_30min_R2 2 TSPTPPESATTVK 13 0 Q5M775;Q5M775-4;J3KSG2 Q5M775 SPECC1 Cytospin-B 1 T(0.231)S(0.769)PTPPESATTVK;T(0.033)S(0.966)PT(0.001)PPESATTVK 120.6 0.00021005 13623500.0 72971.0 73136.0 89692.0 124894.0 108061.0 102821.0 77842.0 101839.0 87828.0 97161.0 True False 96174.260108911 96775.7817475698 88502.62547628822 96101.61789306485 93058.59541863513 96391.58661575022 84769.78720006462 86102.12257741108 92470.40877558422 93759.42296350677 1.0257556741400182 1.032171260111499 0.943933128841198 1.024980901711284 0.9925252574864457 1.0280735905687894 0.9041201888908689 0.918330337964259 0.9862518971727858 1.0 16.51667607036071 -7.249930272325278 24.88519800618621 0.9453697992532307 1.0061786362826575 0.3573323185752977 0.03611257269079501 716.2574542764219 1548707.3624330098 0.01370684172466601 0.01052704806501218 5.624316185339855e-08 7.249930272325278 0.06080883702942674 TS(ph)PTPPESATTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSPTPPESATTVK 13 0 Q5M775;Q5M775-4;J3KSG2 Q5M775 SPECC1 Cytospin-B 1 T(0.163)S(0.833)PT(0.004)PPESATTVK 100.73 0.0021815000000000003 37361000.0 73162.0 87202.0 65956.0 87996.0 122790.0 97584.0 100530.0 95195.0 84690.0 77048.0 True False 85546.88158463278 95858.83826205884 67528.64117952288 83065.86940688109 98730.18095539046 92466.52325318604 91007.07062582824 92696.23211744007 85928.43103226108 91016.19248836745 0.939908375046191 1.053206420102778 0.7419409594414043 0.9126493554154941 1.0847540229504646 1.015934865271407 0.9998997775858359 1.0184586894171315 0.9441004801782208 1.0 16.473835614360873 -6.181188530292663 10.793924534934424 1.0111619842338315 0.9097111211716182 0.28016454287797365 0.07739282115764297 0.9238825357805773 121.22994268261967 0.023433456985941455 0.030266717525466044 6.58887805316166e-07 6.181188530292663 -0.10145086306221329 TS(ph)PTVATQTGASATSTR ddPTM_PC-9_Lapatinib_30min_R1 1 TSPTVATQTGASATSTR 17 0 Q6P1L5;Q6P1L5-2 Q6P1L5 FAM117B Protein FAM117B 1 T(0.175)S(0.825)PTVATQTGASATSTR 95.06700000000001 0.0016866 10870000.0 27983.0 22306.0 26711.0 21334.0 22976.0 21973.0 24251.0 21943.0 25404.0 21233.0 True False 27583.957288546277 22254.35182747655 24514.92468744173 22902.973528137725 21624.596852553997 21033.266011564752 25506.598118945665 22962.551886859856 22542.7340040205 24903.09575880591 1.1076517375873798 0.893637965456855 0.9844127382746412 0.9196837915237536 0.8683497450274786 0.8446044706761906 1.0242340296156294 0.9220761992508556 0.9052181392367346 1.0 14.60403747759629 -4.755051003629408 24.99876267540348 0.92656287848859 1.107652039123061 0.48830859298594154 0.05476525291540635 186.42765002235853 729453.4606692062 0.013656986070538705 0.12560781456001688 1.7577171751859172e-05 4.755051003629408 0.1810891606344711 TS(ph)PVNLPNK ddPTM_PC-9_AZD4547_30min_R2 1 TSPVNLPNK 9 0 P35712-4;P35712-2;P35712-3;P35712 P35712-4 SOX6 Transcription factor SOX-6 1 T(0.228)S(0.772)PVNLPNK 84.507 0.028201999999999998 0.0 23220.0 26129.0 33050.0 39410.0 37757.0 38590.0 28314.0 37517.0 30574.0 37960.0 True False 30603.476993996384 34574.688269556034 32611.735405513613 30324.633378430393 32515.092283260517 36176.9611995779 30833.891148514016 31719.609704894337 32190.079221941898 36631.031954124766 0.8354522207379511 0.9438633427760371 0.890276185676539 0.8278399968749924 0.8876379001274415 0.9876042052237151 0.8417423562385341 0.8659218158150364 0.8787652846432353 1.0 15.160778724170237 -6.533255669185906 24.97340516438563 0.9058337237856888 0.8776195269428577 0.09591498789613317 0.05549016207687704 741.71169856047 1785012.5740377642 0.018446620741764192 0.018466420487027832 2.929168336009009e-07 6.533255669185906 -0.028214196842831107 TS(ph)PYILR ddPTM_PC-9_AZD4547_30min_R2 2 TSPYILR 7 0 P49454 P49454 CENPF Centromere protein F 1 T(0.225)S(0.775)PYILR;T(0.204)S(0.796)PYILR 125.31 0.0046003 11556200.0 64246.0 67230.0 102529.0 105825.0 102264.0 98684.0 78844.0 108347.0 91703.0 98287.0 True False 84674.89160018491 88960.78274569461 101169.39846874138 81428.6812299516 88066.4088051314 92513.27387973931 85860.9632589333 91604.4607163737 96550.23336461498 94846.00204623454 0.8927618431287012 0.9379497377478171 1.066670141978408 0.8585357260526131 0.9285199893001469 0.975405097566916 0.9052670793343371 0.965823110516765 1.0179684043777584 1.0 16.533299341909107 -8.07888045994221 4.410229628375714 1.0071228497042712 0.940491416051218 0.22137479220969591 0.05267686278889071 0.3689235149239677 12.882869041766593 0.03800396815806561 0.01369732561662896 8.339106879127453e-09 8.07888045994221 -0.06663143365305324 TS(ph)PYILR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSPYILR 7 0 P49454 P49454 CENPF Centromere protein F 1 T(0.225)S(0.775)PYILR;T(0.228)S(0.772)PYILR;T(0.241)S(0.759)PYILR 153.04 0.00053121 32166200.0 160089.0 163403.0 181210.0 188922.0 226889.0 187125.0 191088.0 157138.0 151602.0 149802.0 True False 187188.9057981232 179624.5699471946 185530.73364275225 178337.31283338775 182431.7291863145 177311.83558526417 172986.76128268472 153013.29400147355 153818.89244719356 176959.91676802066 1.0578039887050346 1.0150579477422963 1.0484336624432706 1.0077836613540723 1.0309211968350263 1.001988692262468 0.9775477093462673 0.8646777010076294 0.8692301355952659 1.0 17.433063086559727 -7.4896801528187344 2.679968109360996 0.9010222356719849 1.0272238750411529 0.6304784318769056 0.039041929442894356 0.15917447425834502 2.2765950771248527 0.01940600801472948 0.010991827271090925 3.238320634613882e-08 7.4896801528187344 0.12620163936916795 TS(ph)PYILR ddPTM_PC-9_Lapatinib_30min_R1 2 TSPYILR 7 0 P49454 P49454 CENPF Centromere protein F 1 T(0.026)S(0.974)PYILR;T(0.234)S(0.766)PYILR 139.97 0.0027367 27287400.0 80300.0 107746.0 104902.0 108529.0 101778.0 97616.0 87004.0 87549.0 98955.0 75131.0 True False 79154.90727478341 107496.52075689456 96277.36249343032 116510.58470213089 95791.6181432469 93441.19123401024 91508.6414061584 91616.84615333777 87809.6458576542 88117.29324423512 0.8982902715292149 1.2199253608363338 1.0926046289980549 1.3222215573417349 1.087092154291903 1.060418310569514 1.0384867491619774 1.0397147118375836 0.996508660499498 1.0 16.427137559074232 -6.721192899094215 3.1304978284441622 1.0272820928263198 1.1421249608689956 0.1895355845612886 0.10200298079049111 0.39959741963966655 8.026459904926032 0.0360647327157299 0.034371896926785925 1.9002340719860448e-07 6.721192899094215 0.11484286804267585 TS(ph)QDYQALTVHDNLAMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSQDYQALTVHDNLAMK 17 0 Q9BPX3 Q9BPX3 NCAPG Condensin complex subunit 3 1 T(0.432)S(0.568)QDYQALTVHDNLAMK 123.83 2.8975e-05 4392200.0 25493.0 21912.0 23296.0 33149.0 33334.0 25219.0 28747.0 30515.0 18215.0 17215.0 True False 29808.461390298777 24087.278548636918 23851.46499057199 31291.769000508044 26802.441990121184 23896.47124448779 26023.87604974323 29714.013583315078 18481.359915605557 20335.943226134983 1.465801760893494 1.184468223617032 1.172872323911634 1.5387419532275763 1.3179837144546953 1.175085462167152 1.2796985003527317 1.4611573829104594 0.9088026903937269 1.0 14.311744287296076 -8.27136640183416 24.993461505540854 0.9544012751362666 1.315209272159269 0.5828180863937314 0.12504428832609046 554.7020301795982 1396568.2193566326 0.11615216045428448 0.031421771404387795 5.3534481182788475e-09 8.27136640183416 0.36080799702300237 TS(ph)QSEEEEAPR ddPTM_PC-9_AZD4547_30min_R2 1 TSQSEEEEAPR 11 0 Q7RTP6;A0A5F9ZHV5;J3KSK6;Q7RTP6-2;Q7RTP6-4;Q7RTP6-3;Q7RTP6-5 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 T(0.198)S(0.801)QSEEEEAPR 113.53 0.0026919 0.0 3776.9 4161.6 4876.2 6763.1 6136.3 4016.1 3933.1 6397.4 5012.1 5734.3 True False 4977.875635599691 5506.755815476458 4811.538401947519 5203.9717838534 5284.3806652480735 3764.972632122955 4283.138280575705 5408.828827627233 5277.029373595051 5533.543902385079 0.8995818454524447 0.9951589636982777 0.869522043526869 0.9404410402545779 0.9549722128291762 0.6803908487109264 0.7740316795407692 0.9774619887439421 0.9536437167003474 1.0 12.433988020607712 -7.866670623428121 24.96650316169182 0.9741753214998127 0.8762078582078623 0.23054359633998778 0.08657596312288789 17.923018625776255 4211.6127494658085 0.052283364369939564 0.025116120301575926 1.3593440061380048e-08 7.866670623428121 -0.09796746329195039 TS(ph)QSEEEEAPR ddPTM_PC-9_Lapatinib_30min_R1 1 TSQSEEEEAPR 11 0 Q7RTP6;A0A5F9ZHV5;J3KSK6;Q7RTP6-2;Q7RTP6-4;Q7RTP6-3;Q7RTP6-5 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 T(0.226)S(0.774)QSEEEEAPR 154.23 0.00050893 1075400.0 4051.3 4435.9 6129.6 6449.6 6157.0 7454.1 6605.0 5673.2 10561.0 5851.2 True False 3993.527719082571 4425.628946090884 5625.647948940245 6923.925099234888 5794.857365127741 7135.305519355794 6946.974581486794 5936.797583034836 9371.508967739737 6862.572123766077 0.5819287064761633 0.6448936151453027 0.8197579344132231 1.008940230333804 0.8444147851006643 1.0397421536227214 1.0122989538322547 0.8650980238844922 1.3655971549333303 1.0 12.744533691191998 -4.429711998888225 0.4399950555602116 1.076024754298584 1.3555232347360892e-13 0.631247063858901 0.12801982770499526 4.4899570552784835 0.5372049257120179 0.08891952643689688 2.6904317678779592 3.7178169330651526e-05 4.429711998888225 -1.0760247542984485 TS(ph)SEDNLYLAVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSSEDNLYLAVLR 13 0 Q15149-4 Q15149-4 PLEC Plectin 1 T(0.03)S(0.785)S(0.185)EDNLYLAVLR;T(0.015)S(0.614)S(0.371)EDNLYLAVLR 192.54 4.6062e-06 10483400.0 33964.0 35898.0 41205.0 48598.0 51768.0 47135.5 47594.0 37014.5 38176.7 38266.4 True False 39713.43438042241 39461.716198383016 42187.483470832725 45875.21161684181 41624.432019697444 44663.63140269458 43085.55176927957 36042.90859510456 38734.96201427937 45203.79540334426 0.878542034492182 0.8729735157473871 0.9332730381243965 1.014853093805656 0.920817193518622 0.9880504724032593 0.9531401375666793 0.7973425300575102 0.8568962333506556 1.0 15.464156288909045 -10.264292293606593 7.514407371543416 0.9999999989934044 0.915532944587013 0.15299968477918513 0.06121036632365571 4.726148072095505e-11 0.0 0.06510977767393437 0.015791440506468954 5.4413630902539213e-11 10.264292293606593 -0.08446705440639146 TS(ph)SEDNLYLAVLR ddPTM_PC-9_Lapatinib_30min_R1 2 TSSEDNLYLAVLR 13 0 Q15149-4 Q15149-4 PLEC Plectin 1 T(0.004)S(0.599)S(0.398)EDNLYLAVLR;T(0.014)S(0.493)S(0.493)EDNLYLAVLR 172.43 0.00020806 24718500.0 17247.5 18591.8 18985.2 18964.8 20359.7 17614.5 17014.9 15641.5 17614.1 15894.0 True False 17001.547487195872 18548.751829376793 17424.31014099131 20359.534656718213 19162.182474710302 16861.16889640502 17895.848267454912 16368.261192103113 15630.21457330409 18641.25672257623 0.9120386967583295 0.9950376257043119 0.9347175676138247 1.0921760780248788 1.0279447764647318 0.9045081641939213 0.960012971967788 0.8780664005490405 0.8384742941914696 1.0 14.18621150382877 -6.772760543305964 24.95403941606 0.9113290353184885 0.9948708612373047 0.2755754913209296 0.061428995490500064 279.82488362205316 616784.2752331896 0.022091124268539604 0.019654921754178222 1.687483195552332e-07 6.772760543305964 0.0835418259188162 TS(ph)SFTEQLDEGTPNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSFTEQLDEGTPNR 15 0 Q13439-3;Q13439-4;Q13439;Q86W71;C9J0Y3;Q13439-5;E7EVX2;C9JHJ5 Q13439-3;Q13439-5 GOLGA4 Golgin subfamily A member 4 1 T(0.001)S(0.669)S(0.304)FT(0.026)EQLDEGTPNR 246.34 3.3944999999999994e-40 24449000.0 13769.0 15920.0 16805.0 18654.0 26193.0 18436.0 23061.0 17344.0 19479.0 18713.0 True False 16099.819749853841 17500.432388385354 17205.6949333174 17608.87685708399 21060.669678023765 17469.183705276846 20876.49513281833 16888.73837748701 19763.84352435249 22105.51876797352 0.7283167574053617 0.7916770726837672 0.778343865797215 0.7965828371599102 0.9527335639160148 0.7902634581273073 0.9444019546405851 0.7640055207369943 0.894068297233827 1.0 14.432118971122621 -1.5229163585325638 0.0457244027228383 1.3201165661964824 9.683666568470295e-06 0.5032045628160575 0.06332267046712059 518.7910379601672 1.8044973524363028 13.107130162886898 50.102246288954284 0.029997401881093937 1.5229163585325638 -1.320106882529914 TS(ph)SIADEGTYTLDSILR ddPTM_PC-9_Lapatinib_30min_R1 1 TSSIADEGTYTLDSILR 17 0 E7ERV5;A0A087WY00;G3V394;F8WE88;F8W6H6;Q9Y4I1-2;Q9Y4I1;Q9Y4I1-3 E7ERV5 MYO5A Unconventional myosin-Va 1 T(0.109)S(0.535)S(0.356)IADEGTYTLDSILR 140.77 9.2397e-05 5113700.0 5069.2 8232.5 7649.3 7788.7 11109.0 14093.0 13389.0 12909.0 12900.0 9154.0 True False 4996.912278422573 8213.43815205329 7020.404081151886 8361.506980341535 10455.590461134329 13490.275242387566 14082.216907119855 13508.799266621429 11447.066156977813 10736.256703061714 0.46542406880021575 0.7650187937208153 0.6538968166763227 0.7788102698733946 0.9738580913543781 1.2565157126450297 1.3116505404629488 1.2582410834838789 1.0662064510541551 1.0 13.390203451338655 -6.331456081477048 1.8156119427500752 1.203235297952758 0.6421081139692638 0.8162747666057759 0.11519402188368116 0.1387836441841371 0.9033588913689786 0.0408987096482892 0.05125874639123495 4.661695675455324e-07 6.331456081477048 -0.5611271839834943 TS(ph)SLTQFPPSQSEER ddPTM_PC-9_AZD4547_30min_R2 1 TSSLTQFPPSQSEER 15 0 B7Z7F3;Q9H6Z4-3;Q9H6Z4-2;Q9H6Z4 B7Z7F3 RANBP3 Ran-binding protein 3 1 T(0.007)S(0.496)S(0.496)LTQFPPSQSEER 220.52 3.3479e-18 9266600.0 32029.0 39281.0 42415.0 68922.0 55366.0 48502.0 41289.0 55016.0 46876.0 46262.0 True False 42213.555755413865 51977.81506817829 41852.54938653134 53033.09773428511 47679.386586725675 45469.1622726594 44963.6410126084 46514.54134191081 49353.769660749334 44642.3814610569 0.9455937244799141 1.1643154636255313 0.9375070956517132 1.1879540472218697 1.0680296396893176 1.018520087516472 1.00719629063319 1.041936828179452 1.1055362201902768 1.0 15.44612636976349 -10.69137489426993 14.77780913435053 0.9999987494430178 1.0545655184853784 0.03882748486199372 0.07867462866475099 0.0 0.0 0.07096428442968124 0.017211367079408856 2.03528440884978e-11 10.69137489426993 0.054566769042360574 TS(ph)SLTQFPPSQSEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSSLTQFPPSQSEER 15 0 B7Z7F3;Q9H6Z4-3;Q9H6Z4-2;Q9H6Z4 B7Z7F3 RANBP3 Ran-binding protein 3 1 T(0.003)S(0.529)S(0.453)LT(0.016)QFPPSQSEER;TS(0.604)S(0.388)LT(0.009)QFPPSQSEER;T(0.024)S(0.612)S(0.362)LT(0.002)QFPPSQSEER 254.45 6.384099999999998e-129 9370700.0 39317.2 48160.0 42248.6 63726.0 86800.0 86659.0 102725.0 106190.0 99680.0 81072.0 True False 45972.82540990292 52941.006521648174 43255.96685270777 60155.63882247956 69792.1630990136 82114.44948554932 92994.1443354045 103402.62501760508 101137.63142396706 95769.71183440134 0.48003512310234464 0.5527948816760592 0.4516664613912917 0.6281280132334188 0.7287498496361104 0.8574156475226343 0.9710183162731432 1.079700701161157 1.0560502844453326 1.0 16.547281840361343 -6.677763193443593 0.9786176215622684 1.0575741946666615 0.49025317769492666 0.969314403960064 0.04040380791692642 0.08137977414599126 0.16860844540686623 0.022485229998475992 0.02240649193131129 2.1000846788761817e-07 6.677763193443593 -0.5673210169717349 down TS(ph)SLTQFPPSQSEER ddPTM_PC-9_Lapatinib_30min_R1 2 TSSLTQFPPSQSEER 15 0 B7Z7F3;Q9H6Z4-3;Q9H6Z4-2;Q9H6Z4 B7Z7F3 RANBP3 Ran-binding protein 3 1 T(0.014)S(0.597)S(0.375)LT(0.014)QFPPSQSEER;T(0.01)S(0.409)S(0.409)LT(0.172)QFPPSQSEER 162.64 8.7716e-15 11571000.0 16608.4 19563.9 24299.4 21602.1 38042.0 46052.0 44751.0 40490.0 47112.0 39003.0 True False 16371.561170392466 19518.600991552434 22301.597130396527 23190.790496493115 35804.44435344965 44082.46331245529 47067.987811675295 42371.313216012226 41805.7504486464 45744.616581769274 0.35789044468496145 0.4266862955701597 0.48752397105639844 0.5069621789274195 0.7827029064600116 0.9636645053884569 1.028929551252014 0.9262579158418082 0.9138944333245841 1.0 15.481314350535825 -6.344429535040444 1.7453534249695373 0.9707532165023751 0.4190157648713613 0.9720466485595414 0.04196772549185467 0.05772183861650995 0.3482883008807152 0.01650612518277465 0.020603656238818567 4.524498670765432e-07 6.344429535040444 -0.5517374516310138 down TS(ph)STDEVLSLEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSTDEVLSLEEK 13 0 K7ENH8;A0A0A0MRB7;P15923-2;K7EMM4 K7ENH8 TCF3 Transcription factor E2-alpha 1 T(0.192)S(0.269)S(0.269)T(0.269)DEVLSLEEK 76.24 0.017461 3021800.0 13380.0 10658.0 13022.0 12004.0 17229.0 17907.0 20300.0 19536.0 17065.0 15179.0 True False 15644.96973295405 11716.055803731857 13332.493866210007 11331.454797493092 13853.101129411356 16967.925396528128 18377.037040727304 19023.200700103003 17314.54334119182 17930.83254310212 0.8725177537265315 0.6534027784582123 0.7435513010431262 0.6319536346265323 0.7725854946283885 0.9462988043494714 1.024884761850996 1.060921217928674 0.9656296381984014 1.0 14.130154854812076 -6.7936168369863585 2.822205345686859 1.0154224249446475 0.7191844434175139 0.8127539112598643 0.0643709257014973 0.1029926134003314 1.6798507436218808 0.023345527584197782 0.021268119682416417 1.6083596273493075e-07 6.7936168369863585 -0.29623798152713365 TS(ph)STGDAGGGSR ddPTM_PC-9_Lapatinib_30min_R1 1 TSSTGDAGGGSR 12 0 Q8N6G6 Q8N6G6 ADAMTSL1 ADAMTS-like protein 1 1 T(0.003)S(0.332)S(0.332)T(0.332)GDAGGGSR 65.695 0.04102 1785000.0 1266.8 9094.8 4911.2 7071.3 8988.6 5860.3 14882.0 16039.0 9314.0 6789.1 True False 1248.7351996973323 9073.741549382845 4507.420093780233 7591.346991165285 8459.908220267534 5609.66863002653 15652.517141814758 16784.230493248197 8264.95923923189 7962.58688909289 0.15682531532658606 1.1395469431940528 0.5660748393156594 0.953376973702337 1.0624572564295496 0.7045032862009487 1.965757781965996 2.1078866362185824 1.0379741350833092 1.0 12.959021495048855 -7.25012153493623 24.583988581070496 1.6202285264379779 0.7940822249541184 0.4356738274700248 0.4199712711992072 502.108324120841 1090653.1141813735 0.15606552677149022 0.11973225682739091 5.6218397906238305e-08 7.25012153493623 -0.8261463014838595 TS(ph)STLDSEGTFNSYR ddPTM_PC-9_AZD4547_30min_R2 2 TSSTLDSEGTFNSYR 15 0 Q92609;Q92609-2;C9JNM0;C9JED7;F2Z3C3;C9K0P2;C9J397;C9JWX0;C9JW04;C9JDR8 Q92609 TBC1D5 TBC1 domain family member 5 1 T(0.131)S(0.856)S(0.012)T(0.001)LDSEGTFNSYR;T(0.029)S(0.971)STLDSEGTFNSYR 208.79 4.2585e-13 27459000.0 82915.0 110332.0 84862.0 71555.0 80502.0 81466.0 90469.0 103781.0 91042.0 85027.0 True False 109280.24526086145 145994.66134014545 83736.67443215424 55059.10026372962 69325.68686566822 76371.9181416122 98520.56573832408 87744.0311001318 95854.29425407323 82050.23061020457 1.3318700562831849 1.779332736232287 1.0205537974653776 0.6710413834824972 0.8449176358201022 0.9307946799617385 1.2007347816773972 1.069394082717168 1.1682391815502327 1.0 16.324219768129765 -5.315667048625333 8.396958754130067 0.978938379361988 1.5547229097472164 0.6237410404922535 0.17618385019322783 0.20576463987870472 30.094474647957774 0.04904442626110161 0.10287367884936094 4.8342928052077565e-06 5.315667048625333 0.5757845303852284 TS(ph)STLDSEGTFNSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSTLDSEGTFNSYR 15 0 Q92609;Q92609-2;C9JNM0;C9JED7;F2Z3C3;C9K0P2;C9J397;C9JWX0;C9JW04;C9JDR8 Q92609 TBC1D5 TBC1 domain family member 5 1 T(0.166)S(0.832)S(0.002)TLDSEGTFNSYR 107.11 0.00087342 7495000.0 17500.0 33556.0 21398.0 19484.0 20399.0 11479.0 13922.0 15189.0 10114.0 11626.0 True False 20462.404359244854 36887.21791612178 21908.209472366914 18392.374647980294 16401.962385446757 10877.021032375407 12603.207373448544 14790.304844075772 10261.898116191853 13733.701768634639 1.489940928088113 2.685890413054236 1.5952151751541173 1.3392146529630669 1.1942856093544973 0.7919948471006274 0.9176846552931602 1.0769350531445374 0.7472055450940565 1.0 13.745432920070684 -5.8292344083719305 1.5768933501170779 0.9369360307110409 2.0954228635915184 0.679293262785968 0.3051561842516895 0.2042689080731532 1.033592094881355 0.0950255539927689 0.1948001346260077 1.4817181190000361e-06 5.8292344083719305 1.1584868328804774 TS(ph)STLDSEGTFNSYR ddPTM_PC-9_Lapatinib_30min_R1 1 TSSTLDSEGTFNSYR 15 0 Q92609;Q92609-2;C9JNM0;C9JED7;F2Z3C3;C9K0P2;C9J397;C9JWX0;C9JW04;C9JDR8 Q92609 TBC1D5 TBC1 domain family member 5 1 T(0.332)S(0.667)S(0.001)TLDSEGTFNSYR 277.41 4.627699999999999e-75 13435000.0 15020.0 36979.0 30360.0 28072.0 40079.0 31038.0 37752.0 38897.0 26600.0 34292.0 True False 14805.81204566934 36893.377397482975 27863.917992989067 30136.50852544682 37721.63201834573 29710.577093111842 39706.61383804534 40704.29662047981 23604.02788958215 40219.32650878219 0.3681268019850203 0.9173047039817295 0.6927992189751057 0.7493041565195352 0.9378981522753477 0.7387139385992532 0.9872520821395431 1.0120581360702725 0.5868827237678391 1.0 15.295601302799495 -4.755979951762645 24.993781510589276 0.8432707931140654 0.3681260499698875 0.5122160745004924 0.14012766944601543 142.23551710120637 651098.6182869242 0.03377401662789987 0.28531420051880446 1.753961467697106e-05 4.755979951762645 -0.4751447431441779 TS(ph)STLDSEGTFNSYRK ddPTM_PC-9_AZD4547_30min_R2 1 TSSTLDSEGTFNSYRK 16 1 Q92609;Q92609-2;C9JNM0;C9JED7;F2Z3C3;C9K0P2;C9J397;C9JWX0;C9JW04;C9JDR8 Q92609 TBC1D5 TBC1 domain family member 5 1 T(0.126)S(0.536)S(0.126)T(0.207)LDS(0.001)EGT(0.004)FNS(0.002)YRK 80.102 0.020178 0.0 19245.0 22452.0 21022.0 26241.0 26117.0 29461.0 23068.0 29831.0 27210.0 27280.0 True False 25364.50967913265 29709.169927210074 20743.234544469207 20191.54286940856 22491.10536223521 27618.7990127174 25121.00731136261 25221.304398184886 28648.265049684018 26324.935503385765 0.9635164984875427 1.128556228500125 0.7879690547314476 0.767012054666255 0.8543650699293273 1.0491497314082774 0.9542666232983434 0.9580765884475221 1.0882558495157353 1.0 14.6841423761733 -6.761325178224406 24.999999876571632 1.0038493513462452 0.8993218903523875 0.22596129272916077 0.101163631774375 5.766372905589436 1262359.7816702123 0.03819538471494033 0.035902022155440555 1.7325062969759915e-07 6.761325178224406 -0.10452746099385768 TS(ph)SVSSISQVSPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSVSSISQVSPER 14 0 P42356 P42356 PI4KA Phosphatidylinositol 4-kinase alpha 1 T(0.02)S(0.54)S(0.421)VS(0.006)S(0.008)IS(0.002)QVS(0.002)PER 82.529 0.042247 0.0 5132.7 3459.2 7515.2 5858.3 9179.1 8416.6 8577.9 9006.4 7492.3 8647.3 True False 6001.564734554059 3802.6065149436313 7694.390869554712 5530.078443864862 7380.521247720688 7975.218679422498 7765.339213382005 8769.991543069602 7601.860713460968 10214.987038010868 0.587525438086383 0.372257595706563 0.7532452895851169 0.5413691102384126 0.7225189048460969 0.7807370337080219 0.7601908044020509 0.8585416222688966 0.7441870151350926 1.0 13.318399752958886 -4.832735319397705 0.1652007780082893 1.0540483011380053 5.2339853259292826e-20 0.6739414342571495 0.0945797118988109 11.2117362991776 0.3331034298267088 0.3348511859419687 2.556666089694515 1.4698217870460014e-05 4.832735319397705 -1.0540483011380053 TS(ph)TSDLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSTSDLSR 8 0 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 T(0.421)S(0.518)T(0.03)S(0.03)DLSR;T(0.209)S(0.727)T(0.032)S(0.032)DLSR 125.71 0.0034603999999999998 15506400.0 77864.0 96694.0 96165.0 95392.0 105854.0 84129.0 106248.0 80407.0 83168.0 78390.0 True False 91044.83731589967 106293.14129161634 98457.93830779359 90047.49550503663 85112.66857929717 79717.1271393597 96183.42027109345 78296.40144825853 84384.17466160224 92601.4864651015 0.9831898038722253 1.1478556700239881 1.0632436051110175 0.9724195468392682 0.9191285348467206 0.8608622839915481 1.0386811696304883 0.845519920220351 0.9112615561889917 1.0 16.498747731767338 -5.871875035325964 2.9888607740416036 0.9245135901978949 1.0750433711020668 0.4575818475498107 0.06562233677695004 0.20569502031630205 3.682610347706472 0.018727853664837087 0.030293179140897922 1.3431513863315062e-06 5.871875035325964 0.1505297809041719 TS(ph)TSSSSVQAR ddPTM_PC-9_AZD4547_30min_R2 1 TSTSSSSVQAR 11 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 T(0.08)S(0.455)T(0.455)S(0.006)S(0.001)S(0.001)S(0.002)VQAR 99.5 0.011226 0.0 4628.5 5718.2 8314.6 10836.0 7157.9 7263.8 5476.8 9080.6 7327.3 6119.5 True False 6100.266721219305 7566.496324504392 8204.34297133687 8337.92761453112 6164.149139347678 6809.5934377168705 5964.224590032545 7677.401921429309 7714.606119020571 5905.258167630835 1.0330228667490597 1.2813150771255848 1.3893284151924585 1.4119497196980741 1.043840754183438 1.1531406831699709 1.009985409736179 1.300095898179749 1.3063960795664316 1.0 12.527784417784776 -6.267288881710268 24.99858802398156 1.1451799268262168 1.2869636946416312 0.20306771359457276 0.13794755842817147 840.3827372077845 3591476.3787050205 0.044423251190341476 0.0517199270263851 5.403947464442452e-07 6.267288881710268 0.14178376781541435 TSAALS(ph)TVGSAISR ddPTM_PC-9_AZD4547_30min_R2 1 TSAALSTVGSAISR 14 0 A0A087WYR3;O43399;O43399-5;O43399-7;O43399-2;O43399-4;O43399-3;O43399-6 A0A087WYR3 TPD52L2 Tumor protein D54 1 TSAALS(0.936)T(0.064)VGSAISR 104.9 0.0041818 0.0 9726.4 10450.0 17388.0 17261.0 12101.0 11116.0 8804.0 11341.0 10041.0 13481.0 True False 12819.192878312067 13827.758139112115 17157.423758882633 13281.743129791588 10420.985028464534 10420.91476274963 9587.538944392085 9588.509040253928 10571.746760892227 13009.034293297052 0.9854069556044754 1.0629350209520865 1.3188852740378316 1.0209630346377863 0.8010575415143598 0.801052140212978 0.7369908271617129 0.7370653980975697 0.8126465441281336 1.0 13.667226249216084 -6.161539107790793 3.7532064219282515 0.7963078459074345 1.1227310822646048 0.6357524608543355 0.10567737232775253 0.1429348188840447 3.68297907612373 0.03216847075058484 0.042384465371559266 6.893835120688168e-07 6.161539107790793 0.3264232363571703 TSAALS(ph)TVGSAISR ddPTM_PC-9_Lapatinib_30min_R1 1 TSAALSTVGSAISR 14 0 A0A087WYR3;O43399;O43399-5;O43399-7;O43399-2;O43399-4;O43399-3;O43399-6 A0A087WYR3 TPD52L2 Tumor protein D54 1 TSAALS(0.951)T(0.049)VGSAISR 123.1 4.822e-05 4119800.0 9961.8 12615.0 11153.0 9166.3 9940.2 9951.2 9943.2 13962.0 12074.0 7926.0 True False 9819.742905229623 12585.790742563295 10236.043391825004 9840.420279880422 9355.536979185117 9525.610373380203 10458.010243548744 14610.725490786925 10714.098975143414 9295.998539268863 1.056340839959077 1.3538933649136713 1.1011236015781556 1.0585651706281762 1.0064047385189172 1.0247000720946111 1.1250012787083843 1.571722008030357 1.1525495545082223 1.0 13.182394126705978 -7.557584170304639 24.995012649380108 1.2869538798582942 1.1030318439424827 0.11431344332620341 0.1625007943517409 286.4675921333996 206312.30042791198 0.07480495670105457 0.043188856226590334 2.769592214447438e-08 7.557584170304639 -0.18392203591581158 TSAALSTVGS(ph)AISR ddPTM_PC-9_AZD4547_30min_R2 2 TSAALSTVGSAISR 14 0 A0A087WYR3;O43399;O43399-5;O43399-7;O43399-2;O43399-4;O43399-3;O43399-6 A0A087WYR3 TPD52L2 Tumor protein D54 1 TSAALS(0.002)T(0.002)VGS(0.97)AIS(0.025)R;TSAALSTVGS(0.99)AIS(0.01)R 102.65 0.0031024 3784200.0 19962.9 20525.6 33277.0 39657.0 36215.0 32718.0 31129.0 39294.0 29891.0 32022.0 True False 26310.686945885034 27160.09880001528 32835.72523719446 30514.69134454232 31187.17236640302 30672.138287841128 33899.42069513642 33222.01518629204 31470.977236314055 30900.919526738224 0.8514532042685231 0.8789414430374457 1.0626132082827526 0.9875010780225584 1.0092635702771597 0.9925962967315864 1.097035985152598 1.0751141291295683 1.0184479205896306 1.0 14.915362148971237 -5.213356509485997 6.093853568307665 1.0317457812522368 0.8619780412737945 0.7759613438876245 0.03550394347372875 0.09929145130709065 9.085686853035044 0.009696628489732404 0.0259942120775975 6.118479235772101e-06 5.213356509485997 -0.1697677399784423 TSAALSTVGS(ph)AISR ddPTM_PC-9_Lapatinib_30min_R1 2 TSAALSTVGSAISR 14 0 A0A087WYR3;O43399;O43399-5;O43399-7;O43399-2;O43399-4;O43399-3;O43399-6 A0A087WYR3 TPD52L2 Tumor protein D54 1 TSAALS(0.122)T(0.122)VGS(0.755)AIS(0.001)R;TSAALSTVGS(1)AISR 145.61 0.00018698 6473500.0 31704.0 33346.0 32493.0 28720.0 25718.0 28328.0 26578.0 24280.0 32414.0 25197.0 True False 31251.895146198473 33268.78938577212 29821.550966607178 30832.164607111423 24205.317803533417 27116.47747579331 27954.078792847227 25408.137438497823 28763.19398544797 29552.267877107934 1.0575125833373729 1.1257609576401788 1.0091120955799078 1.0433095942188226 0.819068029032167 0.917576870531772 0.945919917520147 0.8597694614896112 0.9732990410434388 1.0 14.850981228379014 -6.118289327657648 6.6872326046312836 0.9137288740385425 1.0632175769542391 0.6032304029625639 0.055534823382800476 0.15883605875679868 8.123527857175493 0.015991421034975188 0.02076728552282106 7.615714808836954e-07 6.118289327657648 0.1494887029156966 TSADAQEPASPVVSPQQS(ph)PPT(ph)SPHTWR ddPTM_PC-9_AZD4547_30min_R2 1 TSADAQEPASPVVSPQQSPPTSPHTWR 27 0 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;F2Z3L2;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 2 TSADAQEPASPVVS(0.004)PQQS(0.62)PPT(0.63)S(0.593)PHT(0.154)WR 86.095 4.2812e-06 2439600.0 6557.2 5129.3 8238.7 12175.0 11773.0 6420.3 7090.4 6054.1 5154.0 9348.0 True False 8642.253201767144 6787.245916071563 8129.449454929047 9368.241851874902 10138.522166772413 6018.837626059858 7721.431864075151 5118.577954378036 5426.429917900456 9020.729365309753 0.9580437292578489 0.7524054476318394 0.9011964693444606 1.0385237681446855 1.1239137941285835 0.6672229464289203 0.8559653606025251 0.567423957320138 0.6015511272035732 1.0 13.13902837104459 -6.78349872328706 24.99623727782208 0.7187424136709025 0.9452431258089807 0.34556987834209685 0.14735543086604844 275.0108690497808 311622.5459554252 0.0532664341395715 0.04701326243075575 1.646270805929624e-07 6.78349872328706 0.2265007121380782 TSADAQEPASPVVSPQQS(ph)PPTS(ph)PHTWR ddPTM_PC-9_Lapatinib_30min_R1 1 TSADAQEPASPVVSPQQSPPTSPHTWR 27 0 H0YDT0;Q96D71-4;E9PMG1;Q96D71-2;F2Z3L2;Q96D71;Q96D71-3 H0YDT0;Q96D71 REPS1 RalBP1-associated Eps domain-containing protein 1 2 TSADAQEPASPVVS(0.001)PQQS(0.953)PPT(0.238)S(0.439)PHT(0.369)WR 92.211 4.5953e-05 0.0 12454.0 10086.0 12355.0 12640.0 13577.0 11678.0 11558.0 11130.0 16879.0 9924.3 True False 12276.403676216112 10062.646486681993 11339.21959167918 13569.587765803923 12778.427553409017 11178.559162747606 12156.416686271672 11647.140432062632 14977.909276250275 11639.70203170148 1.0547008542641843 0.8645106600904152 0.974184696549455 1.1658019877868244 1.0978311574133208 0.9603819008684311 1.044392429734274 1.0006390541906394 1.28679490552739 1.0 13.506766506275985 -5.5822759968356985 10.298039003528805 1.0736295915341711 0.9495719654257724 0.22014459201469727 0.09860954933766602 0.6002713680203653 100.4100237104487 0.026317137535446247 0.0456271649521355 2.616519665273951e-06 5.5822759968356985 -0.12405762610839877 TSAGTFPGSQPQAPAS(ph)PVLPARPPPPPLPR ddPTM_PC-9_AZD4547_30min_R2 2 TSAGTFPGSQPQAPASPVLPARPPPPPLPR 30 1 M0QZX0;F8WAA0;A0A0C4DH07;Q8N2S1-4;Q8N2S1-2;Q8N2S1-3;Q8N2S1 M0QZX0 LTBP4 Latent-transforming growth factor beta-binding protein 4 1 TSAGTFPGSQPQAPAS(1)PVLPARPPPPPLPR;TSAGTFPGS(0.004)QPQAPAS(0.996)PVLPARPPPPPLPR 91.618 1.5115999999999998e-09 19671600.0 8649.6 9781.3 15839.2 14204.5 15839.699999999999 12807.5 7593.5 14078.400000000001 10424.4 14115.2 True False 11399.992877143452 12942.913941253342 15629.161858850563 10929.87198233733 13640.631068124092 12006.645000352268 8269.306789441305 11902.906769448104 10975.41250216561 13621.031144332514 0.8369405191388025 0.9502154281938248 1.147428685335148 0.8024261795249672 1.0014389456704043 0.8814784191539005 0.6070984422410654 0.8738623855507963 0.8057695769040435 1.0 13.733548302466621 -7.002701321063196 24.81597435682826 0.8016164644338859 0.9499168675964041 0.17541770354371378 0.12594153397328003 145.26091127521525 1334467.5858383477 0.04370160880914629 0.03785782237380995 9.937992826778156e-08 7.002701321063196 0.14830040316251825 TSAGTFPGSQPQAPAS(ph)PVLPARPPPPPLPR ddPTM_PC-9_Lapatinib_30min_R1 1 TSAGTFPGSQPQAPASPVLPARPPPPPLPR 30 1 M0QZX0;F8WAA0;A0A0C4DH07;Q8N2S1-4;Q8N2S1-2;Q8N2S1-3;Q8N2S1 M0QZX0 LTBP4 Latent-transforming growth factor beta-binding protein 4 1 TSAGTFPGSQPQAPAS(1)PVLPARPPPPPLPR 100.81 6.0901e-13 7950700.0 10876.0 11065.0 8146.8 8789.1 14686.0 12988.0 11086.0 13179.0 16191.0 8647.2 True False 10720.906245585871 11039.379672331577 7477.001551557427 9435.479733578108 13822.19835378691 12432.533516506764 11659.978835785407 13791.344452304887 14367.399081211453 10141.85699833026 1.0570949923027848 1.088496877263117 0.7372418633775283 0.9303503032168123 1.362886338868964 1.2258636183248923 1.1496887441525834 1.3598441049381265 1.416643824062682 1.0 13.308034216998577 -6.2520406811061076 24.411014420785687 1.2640088185030205 0.9475207458595446 0.5132342110429151 0.1424346318894246 394.75753873047887 1025293.5219664776 0.04294068341460338 0.05464795933772788 5.597051704999268e-07 6.2520406811061076 -0.3164880726434759 TSALS(ph)PNAK ddPTM_PC-9_AZD4547_30min_R2 1 TSALSPNAK 9 0 P50616 P50616 TOB1 Protein Tob1 1 T(0.109)S(0.002)ALS(0.889)PNAK 89.805 0.0090625 7676000.0 37536.0 37646.0 37288.0 61801.0 53526.0 45836.0 45744.0 53529.0 41386.0 48629.0 True False 49471.66720269802 49814.3332923459 36793.53675645363 47553.73426593191 46094.83882601376 42969.86767410867 49815.12738212989 45257.32302405015 43573.57946880642 46926.51351151562 1.0542370080521288 1.061539193192386 0.7840671297138793 1.0133660207733604 0.9822770833955569 0.9156842147150778 1.0615561151779453 0.9644296930975735 0.9285492615621997 1.0 15.518115656312471 TSALS(ph)PNAK ddPTM_PC-9_Lapatinib_30min_R1 1 TSALSPNAK 9 0 P50616 P50616 TOB1 Protein Tob1 1 T(0.002)SALS(0.998)PNAK 83.045 0.01489 5598000.0 36812.0 35007.0 39657.0 48569.0 43119.0 45344.0 40480.0 37965.0 50260.0 43298.0 True False 36287.054129506 34925.943442323674 36396.55454044688 52140.926281434404 40582.82519521569 43404.74282202665 42575.8563298388 39728.99249804651 44599.18953873683 50782.00160904149 0.7145652589449186 0.6877622451988045 0.716721542814623 1.0267599667073968 0.799157652501632 0.8547269002153443 0.8384044539563478 0.7823439651692058 0.8782479643495612 1.0 15.632029640516093 -5.5627799440459755 24.916075406011437 0.8675784890713856 0.7014331674069788 0.5316684625417352 0.07503999308892002 110.98336509700435 69302.42869384837 0.019691453974416604 0.03410665727549692 2.7366550314835936e-06 5.5627799440459755 -0.16614532166440676 TSAPS(ph)PTALK ddPTM_PC-9_Lapatinib_30min_R1 1 TSAPSPTALK 10 0 Q52LR7 Q52LR7 EPC2 Enhancer of polycomb homolog 2 1 T(0.025)S(0.025)APS(0.89)PT(0.059)ALK 66.538 0.045943 2716600.0 25797.0 52622.0 24344.0 32849.0 24431.0 25582.0 25301.0 24678.0 29392.0 23766.0 True False 25429.130049409596 52500.15699208601 22342.530290557508 35264.82504105167 22994.016613194053 24487.91749455465 26610.961981256216 25824.62997146825 26081.563448518755 27873.921433795556 0.9122910857665765 1.8834865814191661 0.8015567649361475 1.2651547836500343 0.8249293759332731 0.8785243064100925 0.9546902844101414 0.9264799727876589 0.9356976739159611 1.0 14.766628361363768 -5.295451841011662 24.995311090688908 0.950388488561758 1.3978895068088986 0.34379570514226354 0.2483970683091714 543.6287902733704 399504.7298597407 0.05949350032246026 0.12385565455647832 5.064635082339075e-06 5.295451841011662 0.4475010182471406 TSAQCGDVITDS(ph)PTHKR ddPTM_PC-9_AZD4547_30min_R2 1 TSAQCGDVITDSPTHKR 17 1 Q14CZ0 Q14CZ0 C16orf72 UPF0472 protein C16orf72 1 TSAQCGDVIT(0.013)DS(0.523)PT(0.463)HKR 61.16 0.015174000000000002 7352800.0 10506.0 12439.0 18177.0 19946.0 23404.0 15785.0 18234.0 17987.0 16640.0 17029.0 True False 13846.68946162471 16459.66349209719 17935.961103359175 15347.757862628076 20154.758582446397 14797.9614546602 19856.79067606148 15207.522450140852 17519.55642876671 16432.81989322421 0.8426240627960728 1.0016335357563342 1.0914718970877761 0.9339698215128897 1.2264942178765597 0.9005126053113919 1.2083617300673444 0.9254359598020917 1.066132078523577 1.0 14.00429244942309 -4.787518583697784 3.3467922629034335 1.0449781931876354 0.8171461875247594 0.24503824423863596 0.10576715848487855 0.4064559720345266 7.258329903434973 0.024333700665857463 0.2388144077919563 1.631103111942607e-05 4.787518583697784 -0.22783200566287598 TSAQCGDVITDS(ph)PTHKR ddPTM_PC-9_Lapatinib_30min_R1 1 TSAQCGDVITDSPTHKR 17 1 Q14CZ0 Q14CZ0 C16orf72 UPF0472 protein C16orf72 1 TSAQCGDVIT(0.03)DS(0.93)PT(0.04)HKR 56.48 0.022347 8221500.0 16541.0 17421.0 18198.0 21136.0 22778.0 18078.0 17215.0 20046.0 21269.0 15304.0 True False 16305.12230675211 17380.662744843044 16701.830686311438 22690.411947629098 21438.24282327101 17304.846081876294 18106.308466358085 20977.410341520877 18873.461247500854 17949.276008701814 0.9083999989106737 0.9683211031139581 0.9305016357325157 1.2641407896691086 1.194379250331754 0.9640971632218982 1.008748679199102 1.1687050960356853 1.051488719564566 1.0 14.131638033084105 -5.654922253877637 22.957432890106688 1.0956284282246636 0.9389730221900395 0.38967277834276204 0.09016667207390282 6.056638422477143 1285.7677470816293 0.025788016524993258 0.044666137324752664 2.2134909267831035e-06 5.654922253877637 -0.15665540603462402 TSAQTT(ph)PSKIPR ddPTM_PC-9_AZD4547_30min_R2 1 TSAQTTPSKIPR 12 1 O95684 O95684 FGFR1OP FGFR1 oncogene partner 1 T(0.001)S(0.001)AQT(0.083)T(0.904)PS(0.012)KIPR 125.47 0.0054511 0.0 18335.0 14985.0 21254.0 29298.0 24870.0 24268.0 17435.0 21771.0 20487.0 24222.0 True False 24165.148608308504 19828.608202353604 20972.158072883092 22543.798749587757 21417.229787448385 22750.518123642294 18986.681223929576 18406.79219781044 21569.90099496056 23373.995152602994 1.0338475921869696 0.848319171493686 0.8972431942404837 0.9644820494915357 0.9162845139489687 0.973326039263285 0.8122993566127767 0.7874902034349317 0.9228161832898505 1.0 14.512616724463431 -7.256267293903987 24.990517895150006 0.8629422864616125 0.9330380267458435 0.11365345392604898 0.07220878130280256 754.5915900490943 3646049.0935759475 0.027302550757545934 0.020513409123500793 5.542844641815474e-08 7.256267293903987 0.07009574028423093 TSASCSPAPES(ph)PMSSSESVK ddPTM_PC-9_AZD4547_30min_R2 2 TSASCSPAPESPMSSSESVK 20 0 A0A2R8YDI1;A0A2R8Y852;P39880-6;P39880-4;P39880-5;P39880-2;P39880;P39880-3 A0A2R8YDI1 CUX1 Homeobox protein cut-like 1 1 TSASCSPAPES(0.793)PMS(0.137)S(0.035)S(0.035)ES(0.001)VK;TSASCSPAPES(0.995)PMS(0.004)S(0.001)SESVK 147.1 1.7247e-14 0.0 14394.7 15400.8 19419.6 26511.0 22246.5 20581.1 17600.4 19320.4 19326.5 20403.0 True False 18971.91517163995 20378.80742094142 19162.08341545876 20399.29854086698 19157.95747754205 19294.160563478436 19166.801503507304 16334.876118624637 20348.059334168272 19688.697180189873 0.9635942387660305 1.0350510871509524 0.9732529907940799 1.036091842653362 0.9730434320874296 0.9799612634040404 0.9734926251388699 0.8296575425549365 1.033489374535245 1.0 14.265080029444864 -7.045912132015651 1.9347325029077034 0.9452679005093786 0.9999485132031986 0.07768254873724778 0.054703994285175105 0.623606199616935 4.655856927561472 0.024018141816281386 0.017922010278614734 8.996795894504078e-08 7.045912132015651 0.05468061269381996 TSASEGNPYVSSTLS(ph)VPASPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSASEGNPYVSSTLSVPASPR 21 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 TSASEGNPY(0.007)VS(0.031)S(0.031)T(0.031)LS(0.476)VPAS(0.423)PR 100.39 0.00020094 55105000.0 7831.4 7147.9 9802.1 15481.0 14166.0 14292.0 13011.0 18561.0 9061.1 11020.0 True False 9157.101342799433 7857.496273174604 10035.819238671264 14613.64976007919 11390.273991481876 13542.502360371918 11778.503888517376 18073.79341700511 9193.601445582957 13017.838765727996 0.703427159269117 0.6035945301351402 0.770928217753973 1.1225864771464582 0.874974271571791 1.0403034331647432 0.9047971864213428 1.388386639461836 0.7062310120007715 1.0 13.668202330297317 -5.595268708725865 4.84197079971849 1.0123894206660247 0.6597606941514366 0.42822472256833277 0.16870564059799686 0.17056427571614083 7.462951127065033 0.04349111496472336 0.07817751466298335 2.5394010292253807e-06 5.595268708725865 -0.3526287265145881 TSASEGNPYVSSTLSVPAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 4 TSASEGNPYVSSTLSVPASPR 21 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 TSASEGNPYVSSTLSVPAS(1)PR;TSASEGNPYVSSTLS(0.001)VPAS(0.999)PR;TSASEGNPYVSSTLSVPAS(1)PR;TSASEGNPYVSSTLSVPAS(1)PR 343.85 2.049799999999999e-233 225077000.0 101025.0 97756.0 161444.0 233316.0 204935.0 192114.0 153932.0 220393.0 192223.0 182527.0 True False 133148.84854946073 129353.71527722916 159303.1470743642 179528.6008962665 176483.31268559495 180101.0812100465 167631.64979420303 186336.3259773114 202383.51534896763 176136.78528689506 0.755940040194246 0.7343935286801975 0.9044286053869334 1.0192567134902955 1.0019673766506836 1.022506916523396 0.9517128947321327 1.0579069311035916 1.1490133365345654 1.0 17.42633671471836 -5.480052924310729 2.2030775998759697 1.0285339536796496 0.7375072767933065 0.8428091336090046 0.0488461082881721 0.12123428222031055 1.1441386497477166 0.014777239770481643 0.03836729768308004 3.3109077139912533e-06 5.480052924310729 -0.2910266768863431 TSASEGNPYVSSTLSVPAS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TSASEGNPYVSSTLSVPASPR 21 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 TSASEGNPYVSSTLSVPAS(1)PR;TSASEGNPYVSSTLSVPAS(1)PR;TSASEGNPYVSSTLSVPAS(1)PR;TSASEGNPYVSSTLS(0.001)VPAS(0.999)PR 369.23 9.496399999999995e-287 116702000.0 63138.6 76817.4 96033.6 112111.6 130038.3 111432.2 105228.0 131321.5 110387.7 86150.9 True False 73826.71793580662 84443.32380348959 98323.40523345626 105830.35052271144 104558.22860274729 105588.49926682316 95260.04205525391 127874.44977163093 112001.91127948924 101769.37619985073 0.725431565885091 0.8297518070432415 0.9661394115295804 1.0399036967160527 1.0274036503615775 1.0375272327450704 0.936038380231259 1.2565120721632024 1.1005463083466707 1.0 16.63494397444328 -3.9984216576926 0.549623221999866 1.0860992049017928 6.753333590073325e-10 0.6777060367098913 0.07796811698023744 5.191669974849103 0.6280939836109273 0.0422125598534678 4.3510808255965445 0.00010036408794261256 3.9984216576926 -1.0860992042264594 TSASEGNPYVSSTLSVPAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 4 TSASEGNPYVSSTLSVPASPR 21 0 E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;G5E9V3;A0A1W2PQ63;E9PDY7 E9PFQ4 PHLDB2 Pleckstrin homology-like domain family B member 2 1 TSASEGNPYVSSTLSVPAS(1)PR;TSASEGNPYVSSTLSVPAS(1)PR;TSASEGNPYVSSTLSVPAS(1)PR;TSASEGNPYVSSTLSVPAS(1)PR 304.25 1.2927999999999997e-148 205803000.0 177612.0 163377.0 170713.0 149902.0 176927.0 156203.0 143756.0 139709.0 180327.0 137013.0 True False 175079.220309948 162998.7105943532 156677.63611123673 160926.29313841273 166520.50171186554 149522.5618169777 151198.98227648987 146200.39017277965 160016.67433250695 160695.51449165298 1.0895090685250095 1.0143326720100818 0.9749969475306982 1.001436123761698 1.0362485987156482 0.9304712847149467 0.940903563828744 0.9097975798221408 0.9957756122733513 1.0 17.293970133935424 -6.7609264462601315 24.99999741406401 0.948846574706819 1.0189075585613758 0.43993672177910725 0.03779442669393894 13.089098067820682 637968.5853558775 0.01296518590046303 0.012220053148703922 1.7340976661599043e-07 6.7609264462601315 0.07006098385455684 TSAVS(ph)SPLLDQQR ddPTM_PC-9_AZD4547_30min_R2 1 TSAVSSPLLDQQR 13 0 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 T(0.074)S(0.003)AVS(0.461)S(0.461)PLLDQQR 217.2 1.5862e-14 73601000.0 55454.0 54470.0 59058.0 90389.0 79008.0 66788.0 61773.0 79645.0 67092.0 72093.0 True False 73087.21848514528 72076.36228109447 58274.852332188326 69551.21254612893 68039.10297735098 62611.73580195408 67270.67732984241 67337.6953100278 70638.34614896736 69569.0460134015 1.0505709460363457 1.0360406877968396 0.8376549007293056 0.9997436580161077 0.9780082792028542 0.8999941696755882 0.9669627684255387 0.967926098872423 1.0153703435197297 1.0 16.086157916997784 -8.222153749522247 6.690832714391874 1.0076765558043415 0.9641938065553364 0.06954572958143379 0.05860825173580526 0.5403672520482863 72.8266574737808 0.042474620891380835 0.015289207037778658 5.995787749859972e-09 8.222153749522247 -0.04348274924900508 TSAVS(ph)SPLLDQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSAVSSPLLDQQR 13 0 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 TSAVS(0.678)S(0.322)PLLDQQR 257.2 6.704199999999999e-44 48370000.0 84434.0 97438.0 105250.0 100670.0 119730.0 105720.0 103900.0 99304.0 95257.0 74570.0 True False 98727.00855248432 107111.00069469151 107759.55916284783 95029.78627654353 96269.76598899657 100175.85709057642 94057.83982914122 96697.3752212853 96649.9534164613 88088.95070420482 1.1207649513728593 1.215941384684682 1.2233039251959674 1.0787934867750377 1.0928699368012933 1.1372125140525104 1.0677597936769552 1.0977242258905642 1.0971858859007595 1.0 16.4266734479124 -1.5228787455810142 0.05972007564003281 0.8233607960312617 1.7254059436127132 0.5518533925212367 0.042489300466856984 261.96817174993276 1.173702010590377 3.61277122580097 20.60036503956195 0.02999999997922999 1.5228787455810142 0.9020451475814515 TSAVS(ph)SPLLDQQR ddPTM_PC-9_Lapatinib_30min_R1 1 TSAVSSPLLDQQR 13 0 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 T(0.002)SAVS(0.499)S(0.499)PLLDQQR 230.69 5.1274000000000006e-20 63262000.0 254450.0 224070.0 266550.0 218840.0 232260.0 230040.0 207140.0 179550.0 210590.0 177280.0 True False 250821.49633958424 223551.17968181963 244635.28791275434 234934.22362883927 218598.9234407293 220201.7254494311 217864.69565619616 187892.5484795013 186871.13658898883 207922.6117892487 1.2063214009345844 1.075165311545875 1.176568944606745 1.1299118532955408 1.0513475256952916 1.0590561726524894 1.047816270589294 0.903665776716724 0.8987533149035385 1.0 17.665687135674546 -7.09393258219164 0.8944125008703305 0.9275563201483636 1.1458644840045276 0.7370190428297196 0.049750323435336315 0.29679528907420905 0.481777223272442 0.035846899499781724 0.02404856272857662 8.055034740196038e-08 7.09393258219164 0.21830816385616392 TSAVSS(ph)PLLDQQR ddPTM_PC-9_AZD4547_30min_R2 3 TSAVSSPLLDQQR 13 0 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 TSAVS(0.02)S(0.98)PLLDQQR;TSAVS(0.214)S(0.786)PLLDQQR;TSAVS(0.062)S(0.938)PLLDQQR 261.02 1.8935999999999998e-44 145316000.0 142794.0 150009.0 174430.0 256585.0 233957.0 194354.0 181315.0 226806.0 178168.0 187601.0 True False 188199.5217002892 198496.47566412148 172116.94422946274 197433.29244873257 201476.10894177938 182201.01365594106 197451.68374630273 191758.34418339087 187585.59674281903 181033.14609130056 1.039585986123085 1.0964648184593424 0.9507482355891826 1.09059195352635 1.1129238666612402 1.0064511256079676 1.0906935443011183 1.0592443887965206 1.036194756556978 1.0 17.465894344803445 TSAVSS(ph)PLLDQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TSAVSSPLLDQQR 13 0 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 TSAVS(0.132)S(0.868)PLLDQQR;TSAVS(0.043)S(0.957)PLLDQQR;T(0.043)S(0.001)AVS(0.137)S(0.819)PLLDQQR;TSAVS(0.023)S(0.977)PLLDQQR;TSAVS(0.045)S(0.955)PLLDQQR 205.26 8.6868e-10 149611100.0 210298.0 230280.0 224041.0 247687.0 265532.0 199051.0 252735.0 219814.0 219509.0 162401.0 True False 245897.2978251699 253140.67653249923 229382.98712022364 233809.90040208885 213502.91073741147 188612.4151507411 228794.11115705484 214044.1154121845 222718.9038547716 191843.01573439126 1.2817630961640918 1.319519897888674 1.1956806779862494 1.2187563853030814 1.1129042666479376 0.9831601866177762 1.1926111059149673 1.1157253475859183 1.160943508952801 1.0 17.5495667173615 -5.8297814470050895 1.3831847522117444 1.0999159673985928 1.2973430058436286 0.598699765979777 0.06555163720295029 0.3153907154837083 1.2190225396800471 0.0226190527096865 0.04983470879284618 1.4798529173626222e-06 5.8297814470050895 0.19742703844503584 TSAVSS(ph)PLLDQQR ddPTM_PC-9_Lapatinib_30min_R1 3 TSAVSSPLLDQQR 13 0 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 TSAVS(0.027)S(0.973)PLLDQQR;TSAVS(0.039)S(0.96)PLLDQQR;TSAVS(0.019)S(0.981)PLLDQQR 234.83 7.3215e-26 145466000.0 391971.0 399556.0 412714.0 365608.0 405972.0 361995.0 337342.0 362473.0 368293.0 295788.0 True False 386381.42166132305 398630.8526306475 378782.248042112 392496.03195253445 382093.52513166115 346513.3177015599 354807.9181329172 379314.8188527445 326811.96404277784 346914.56168726395 1.1137653599263948 1.149075007667175 1.0918603306815817 1.131391055029743 1.1014052661073082 0.9988433924948191 1.0227530271639877 1.093395494867375 0.9420531742838509 1.0 18.4042208732424 -6.671934119136411 4.973685587562762 1.0180963452659626 1.1206097685382306 0.666389002793438 0.03752428934996897 0.13283609121910353 5.565561310758612 0.012245725969397298 0.012127230409695043 2.1284619012773402e-07 6.671934119136411 0.10251342327226798 TSCDSLDLSSAALPDS(ph)SPSK ddPTM_PC-9_AZD4547_30min_R2 1 TSCDSLDLSSAALPDSSPSK 20 0 Q8NEV8-2;Q8NEV8;E9PPH6;F5GXG5 Q8NEV8-2 EXPH5 Exophilin-5 1 TSCDSLDLSSAALPDS(0.49)S(0.49)PS(0.02)K 80.738 0.0013779999999999999 4432700.0 6479.4 8725.5 9646.2 9117.4 9166.3 8887.4 10163.0 9474.4 12224.0 10293.0 True False 8539.714420107668 11545.847238547636 9518.285085284882 7015.52429242581 7893.71746685518 8331.66947305335 11067.487311660234 8010.349180053065 12870.135684209385 9932.645202945372 0.8597623538969607 1.162414140708851 0.9582830042557428 0.7063097643259688 0.7947245980873675 0.8388167807083982 1.1142537647854713 0.8064668591683632 1.2957410056681522 1.0 13.277962263540577 -8.254876413060439 24.993042015462652 1.1478705069004922 0.9099298615536401 0.29526736855328195 0.14985921394880383 623.1521762885419 2373106.6522679324 0.10963263641574578 0.039279245967498294 5.560624731468484e-09 8.254876413060439 -0.2379406453468521 TSCS(ph)PQKAQEANK ddPTM_PC-9_AZD4547_30min_R2 1 TSCSPQKAQEANK 13 1 Q8IY33-4;Q8IY33-2;Q8IY33;Q8IY33-5 Q8IY33-4 MICALL2 MICAL-like protein 2 1 T(0.016)S(0.016)CS(0.968)PQKAQEANK 69.03 0.014842 6690400.0 21302.0 15366.0 25001.0 52466.0 45545.0 27603.0 19530.0 24169.0 19928.0 35912.0 True False 28075.592890874686 20332.759001492515 24669.470404636802 40370.77429161958 39221.86291392591 25876.98004643557 21268.1321653768 20434.2363983685 20981.353396181672 34654.73181076206 0.8101517866069817 0.5867238884583766 0.7118644154959431 1.1649426263654534 1.131789538239783 0.7467084203029223 0.6137150990379894 0.5896521291797338 0.6054397855609979 1.0 15.08076473317731 -6.990644078612669 24.766697472007056 0.6697497236625437 0.8779222914166931 0.1525152902267537 0.19660883449269742 329.5673410040781 872415.2941673486 0.07575999924569392 0.0667257930883999 1.0217765266657856e-07 6.990644078612669 0.20817256775414938 TSDDEVGS(ph)PKEESR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSDDEVGSPKEESR 14 1 B8ZZI9;Q6ULP2-7;Q6ULP2-8;Q6ULP2-6;Q6ULP2;Q6ULP2-9 B8ZZI9 AFTPH Aftiphilin 1 TSDDEVGS(0.996)PKEES(0.003)R 55.912 0.034388999999999996 10997000.0 27219.0 22438.0 22407.0 29180.0 29702.0 33135.0 45978.0 31135.0 33887.0 23044.0 True False 31826.639100244887 24665.49635242404 22941.267859020707 27545.13920283641 23882.106317591046 31397.342269166224 41622.630988106386 30317.73924025935 34382.53326709447 27221.694783796367 1.1691644973989497 0.906097013735754 0.8427567806203025 1.0118818619343486 0.87731886303445 1.1533941041707438 1.5290242330129324 1.1137344489772876 1.2630563063825317 1.0 14.732469269318027 -6.922266931735435 5.562820140409769 1.249870226843629 0.9565840628714429 0.4075446922532948 0.15157886940779194 0.18322079187741058 9.724184299108682 0.05263022639006752 0.04619672996019118 1.196005201044831e-07 6.922266931735435 -0.2932861639721861 TSDDEVGS(ph)PKEESR ddPTM_PC-9_Lapatinib_30min_R1 1 TSDDEVGSPKEESR 14 1 B8ZZI9;Q6ULP2-7;Q6ULP2-8;Q6ULP2-6;Q6ULP2;Q6ULP2-9 B8ZZI9 AFTPH Aftiphilin 1 T(0.001)S(0.001)DDEVGS(0.997)PKEESR 57.148 0.032189999999999996 8114000.0 12455.0 11578.0 12886.0 12889.0 13211.0 9868.4 10143.0 10511.0 15770.0 13118.0 True False 12277.389416032727 11551.191852350203 11826.562821398462 13836.900056443563 12433.954953825332 9446.351536363976 10668.15490991984 10999.37943229203 13993.816534537988 15385.42882136372 0.7979881197061426 0.7507877737090164 0.7686859403604319 0.8993509519364246 0.8081643416113262 0.6139803866400573 0.6933934070856952 0.7149218627574838 0.909549983755189 1.0 13.909277034454783 -8.449005214309734 3.788401810569346 0.998118870850476 0.7563785275075632 0.5652832626362909 0.07173232842910532 0.1666226221626662 4.541061915511868 0.07694930927096567 0.02026516272024204 3.5562704874564817e-09 8.449005214309734 -0.24174034334291283 TSDIFGS(ph)PVTATSR ddPTM_PC-9_AZD4547_30min_R2 3 TSDIFGSPVTATSR 14 0 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2;H3BMV3;H3BMT0;H3BTV5 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 TSDIFGS(0.999)PVT(0.001)ATSR;T(0.114)S(0.422)DIFGS(0.464)PVTATSR;T(0.01)S(0.045)DIFGS(0.94)PVT(0.005)ATSR 199.33 6.2968e-08 443967000.0 237388.0 185589.0 264901.0 358944.0 324828.0 279725.0 272743.0 336831.0 268302.0 287235.0 True False 312872.44602286024 245577.01485929923 261388.2396567616 276195.00642951805 279731.23913941614 262233.7515302391 297016.5986267984 284781.50855636835 282483.89597061096 277178.9900775291 1.1287740313049968 0.8859871189753936 0.9430304929809049 0.9964500063740912 1.009207945599243 0.946080911316151 1.0715696689122094 1.0274281917136387 1.0191389177498555 1.0 18.080458381047222 -7.257602640287652 24.99624260405569 1.0318198766966862 0.9801485046868728 0.10998737041905471 0.061136812060295365 686.0856037327674 4469850.336252137 0.023339284294811 0.017400619380188595 5.525827961999471e-08 7.257602640287652 -0.05167137200981342 TSDIFGS(ph)PVTATSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TSDIFGSPVTATSR 14 0 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2;H3BMV3;H3BMT0;H3BTV5 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 T(0.003)SDIFGS(0.994)PVT(0.003)ATSR;TSDIFGS(0.978)PVT(0.013)AT(0.005)S(0.003)R;T(0.003)S(0.124)DIFGS(0.873)PVTATSR;T(0.004)S(0.001)DIFGS(0.992)PVT(0.002)ATSR 227.91 1.3454999999999999e-20 292045400.0 242713.0 230570.0 288236.0 304502.0 353318.0 328598.0 319059.0 327528.0 295741.0 259166.0 True False 283799.5170997371 253459.46581595563 295108.6393811167 287441.74014880403 284087.8742144852 311365.7424162811 288835.4217328771 318930.7370446008 300065.6526379967 306150.7442430728 0.9269927394800332 0.8278910653724161 0.9639324578835939 0.9388895684688766 0.9279346189958287 1.0170340862182186 0.9434418408715415 1.0417441180263183 0.9801238712643966 1.0 18.223882664680275 -5.98746928673954 0.6140720098828063 1.0038247183819693 0.8698538015805234 0.4997736953809322 0.04009846121328348 0.882503124335129 0.620751918921498 0.024768927648605922 0.06979031466162822 1.0292733147220918e-06 5.98746928673954 -0.1339709168014459 TSDIFGS(ph)PVTATSR ddPTM_PC-9_Lapatinib_30min_R1 4 TSDIFGSPVTATSR 14 0 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2;H3BMV3;H3BMT0;H3BTV5 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 T(0.004)SDIFGS(0.97)PVT(0.026)ATSR;T(0.004)SDIFGS(0.996)PVTATSR;T(0.217)S(0.019)DIFGS(0.764)PVTATSR;T(0.001)S(0.003)DIFGS(0.984)PVT(0.007)AT(0.004)S(0.001)R 214.58 2.6175e-15 645514000.0 279867.0 248671.0 271334.0 260135.0 273289.0 256891.0 234421.0 243263.0 288160.0 243766.0 True False 275876.04525867844 248095.21757780027 249025.9658995291 279266.19568492053 257214.67832684662 245904.37077216964 246558.17234923784 254565.8870552422 255704.38634067646 285900.62830222235 0.9649368275156534 0.8677673045039327 0.8710228003986286 0.9767946203661761 0.8996646137305717 0.8601043384634569 0.8623911525252193 0.8903998867261791 0.8943820370704965 1.0 18.12515426491126 -6.512045802631159 24.625586286559386 0.8907995669654094 0.9160508719864585 0.009538411394426904 0.04911764775539902 1465.1568390598507 3330622.990068846 0.015386777278293077 0.01637754005472786 3.075772412971105e-07 6.512045802631159 0.02525130502104911 TSDIFGSPVTATS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 TSDIFGSPVTATSR 14 0 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2;H3BMV3;H3BMT0;H3BTV5 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 TSDIFGS(0.035)PVT(0.014)AT(0.229)S(0.721)R 91.712 0.01957 0.0 8196.2 10304.0 12818.0 17501.0 15499.0 15035.0 10058.0 13210.0 11727.0 15387.0 True False 10802.421108449313 13634.566494297736 12648.02494486759 13466.414837754635 13347.231382214022 14094.859073222435 10953.142515072184 11168.698035601306 12346.865278855 14848.305813438288 0.7275187650481111 0.9182573867759329 0.8518160323328363 0.906932750911354 0.8989060132459196 0.9492570566849482 0.7376695127843588 0.7521866922685014 0.8315336061896443 1.0 13.858010708960238 -9.525580741854744 11.619580621233872 0.9999985789905074 0.8452134968743523 0.2822141672965014 0.07560099370883946 0.0 0.0 0.0769337942665488 0.018659185878854068 2.9813932107051154e-10 9.525580741854744 -0.15478508211615505 TSDLRDEAS(ph)SVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSDLRDEASSVTR 13 1 E7ERS3;Q86VM9 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 TSDLRDEAS(0.499)S(0.499)VT(0.002)R 126.09 0.00064484 7026000.0 12620.0 23414.0 16417.0 16406.0 18114.0 12512.0 18382.0 11572.0 10117.0 11691.0 True False 14756.31674363828 25738.387182264723 16808.44354181921 15486.825008969656 14564.691732437008 11855.848693882845 16640.723885844793 11268.247261547504 10264.941985516409 13810.485754094914 1.0684864389554813 1.8636844236006034 1.2170783737158108 1.1213816287654976 1.0546111115692267 0.858467175230784 1.2049340032019287 0.8159196904574035 0.7432716103032636 1.0 13.75347644372899 -5.798579534604519 1.8064073725046907 0.9456237451489989 1.4708482599452093 0.4496406115016379 0.2210033951061852 0.2944727694649887 1.9609846656359826 0.0673782858305279 0.1337934318337645 1.590085456546556e-06 5.798579534604519 0.5252245147962104 TSDLRKMVDMLQDS(ph)FPARFK ddPTM_PC-9_Lapatinib_30min_R1 1 TSDLRKMVDMLQDSFPARFK 20 3 P12271 P12271 RLBP1 Retinaldehyde-binding protein 1 1 TSDLRKMVDMLQDS(1)FPARFK 56.817 0.027804000000000002 651840.0 611.74 709.14 956.94 1007.6 787.28 900.22 765.25 907.19 755.74 850.81 True False 603.0164754206235 707.498029899432 878.2640870952231 1081.7022652550652 740.9737382520334 861.7196891153155 804.8709006029932 949.3413592599194 670.620602904993 997.8713748669369 0.6043028095690528 0.7090072405311504 0.880137570047379 1.0840097155801336 0.7425543581213961 0.8635578801227997 0.806587823716579 0.9513664618213056 0.672051147869051 1.0 9.962710054635028 -5.088639929003344 3.1899220674267768 0.8728850635957889 0.6170964722958259 0.38513143131460115 0.11376545314509048 0.2587302557133401 4.853167926569169 0.029011026697807748 0.1103578589779747 8.153800306336175e-06 5.088639929003344 -0.255788591299963 TSDPTQDLHFTPLLS(ph)PSSSTSASSTAK ddPTM_PC-9_AZD4547_30min_R2 2 TSDPTQDLHFTPLLSPSSSTSASSTAK 27 0 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 TSDPTQDLHFTPLLS(0.98)PS(0.012)S(0.004)S(0.002)T(0.002)S(0.001)ASSTAK;TSDPTQDLHFTPLLS(0.967)PS(0.023)S(0.008)S(0.002)T(0.001)SASSTAK 117.11 3.4815e-12 20639800.0 40606.4 24847.3 92868.0 171284.0 114379.0 104269.0 67869.0 122231.0 80947.0 102923.0 True False 53518.39053441059 32878.703809565595 91636.50964112673 131797.12011142005 98499.45017525395 97749.04294684595 73909.20952032549 103343.00753895406 85225.69316342432 99319.69709732298 0.5388497156004023 0.33103910674785775 0.9226418557371604 1.3269988125544985 0.9917413469227029 0.9841858745406971 0.7441546005512093 1.0405086861842587 0.8580945739283922 1.0 16.599792241176402 -5.31644808844645 5.999665610691227 0.9916252370250922 0.4356000160768412 0.6882420532877014 0.14787644805261743 0.10839917767286421 8.763896115517499 0.04031873917717945 0.08681296504986476 4.825606574591779e-06 5.31644808844645 -0.556025220948251 TSDPTQDLHFTPLLS(ph)PSSSTSASSTAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSDPTQDLHFTPLLSPSSSTSASSTAK 27 0 Q9C0D5;Q9C0D5-2 Q9C0D5 TANC1 Protein TANC1 1 TSDPTQDLHFT(0.005)PLLS(0.803)PS(0.119)S(0.033)S(0.01)T(0.011)S(0.004)AS(0.005)S(0.005)T(0.005)AK 70.07300000000001 0.00012069 4900500.0 2187.9 3758.0 7365.7 6661.0 10192.0 10784.0 9892.2 6533.6 8393.8 6627.2 True False 2558.268257005245 4131.069404243223 7541.326222572804 6287.805765253374 8194.950763884177 10218.468055852985 8955.13920267402 6362.099922921423 8516.543445490526 7828.6588991136605 0.326782440003215 0.5276854512988083 0.9632973309677105 0.8031778937213963 1.0467885840334654 1.3052641822228188 1.1438918616939482 0.8126679173161732 1.087867482188392 1.0 12.934549470171946 -4.9779265496535725 1.0127913046211676 1.060001720190215 0.05740003069243822 0.7634267048687353 0.13573079661861698 0.7202203356465227 0.7420012014354151 0.04902175019684346 0.731773655104403 1.0521398026285906e-05 4.9779265496535725 -1.0026016894977767 down TSDS(ph)DQQAYLVQR ddPTM_PC-9_AZD4547_30min_R2 1 TSDSDQQAYLVQR 13 0 Q96CV9-3;Q96CV9-2;Q96CV9 Q96CV9-3 OPTN Optineurin 1 T(0.276)S(0.309)DS(0.415)DQQAYLVQR 128.85 9.9945e-05 17061000.0 19373.0 22443.0 30037.0 36564.0 32772.0 32629.0 26160.0 30580.0 28348.0 29174.0 True False 25533.211016567253 29697.260853214677 29638.689754172832 28134.73470816869 28222.173485897005 30588.70347191051 28488.18932136492 25854.563658492643 29846.417406411 28152.627139874498 0.9069566008780336 1.0548664146214763 1.0527859303117584 0.9993644489511792 1.0024703323663888 1.0865310480592993 1.011919391388349 0.9183712599906192 1.0601645543814087 1.0 14.780981937194865 -11.288556740998102 4.3321805009234975 0.998845053333295 1.0119587873098606 0.0023679021055373894 0.05605842688890731 0.0006721172659973068 3.635390106177222e-05 0.05833921472437031 0.012901958628284242 5.1456857373519735e-12 11.288556740998102 0.013113733976565567 TSDS(ph)TPDPQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSDSTPDPQR 10 0 P52948-6;P52948-2;P52948-5;P52948;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 T(0.001)S(0.001)DS(0.499)T(0.499)PDPQR 111.5 0.0015869999999999999 6545000.0 17274.0 16888.0 18534.0 16078.0 16022.0 11968.0 18893.0 14355.0 12205.0 11183.0 True False 20198.14702294832 18564.529031096223 18975.920850586408 15177.201785579296 12882.60411488936 11340.377011540111 17103.31826652515 13978.196460379744 12383.475035408508 13210.38937542071 1.5289592493412083 1.4052976413880307 1.436439177628864 1.1488837576444222 0.9751873127115218 0.8584438118561479 1.2946869150085492 1.0581214575240014 0.9374042417288048 1.0 13.689385370109182 -5.8416747387008 2.980444185170266 1.0300549470598601 1.4611808593621134 0.7580888510159456 0.11013542905380574 0.13035697280479835 2.332629110229746 0.03378641622460376 0.05579064295089343 1.439876558301805e-06 5.8416747387008 0.4311259123022533 TSDS(ph)TPDPQR ddPTM_PC-9_Lapatinib_30min_R1 2 TSDSTPDPQR 10 0 P52948-6;P52948-2;P52948-5;P52948;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 T(0.168)S(0.027)DS(0.479)T(0.325)PDPQR;T(0.021)S(0.014)DS(0.482)T(0.482)PDPQR 97.163 0.0052513 10083300.0 19362.6 32289.3 33922.5 36079.3 35896.8 36724.7 38027.8 36182.1 35314.1 29264.7 True False 19086.485773334032 32214.536109698685 31133.522994636765 38732.69207901655 33785.4207998242 35154.07019045702 39996.69341254557 37863.252455250076 31336.65418404108 34323.064402238386 0.5560833831634597 0.9385681806312669 0.9070729416749393 1.1284741835723326 0.9843357925121883 1.0242112935628336 1.165300771044708 1.103143122989357 0.9129911541930228 1.0 15.06689074359177 -4.45637719648064 1.279691420147254 1.0462810633599398 1.133121355211581e-12 0.7574860365738353 0.0800923475216255 1.351912912259707 1.1224876330691624 0.023352906011292963 2.268291905657838 3.496413621550299e-05 4.45637719648064 -1.0462810633588067 TSDS(ph)TPDPQRVPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSDSTPDPQRVPLR 14 1 P52948-6;P52948-2;P52948-5;P52948;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 T(0.012)S(0.076)DS(0.498)T(0.414)PDPQRVPLR 70.529 0.012828999999999998 8678400.0 37819.0 23763.0 27983.0 38784.0 44705.0 42710.0 32814.0 34303.0 46452.0 33001.0 True False 44221.00974070175 26122.03359580408 28650.22084611846 36611.05821942454 35945.3761675277 40470.21241334207 29705.620367213065 33402.58259703284 47131.27262144989 38983.820064227715 1.1343426495362825 0.670073726811964 0.7349259461724338 0.9391347015019582 0.9220588466780825 1.0381284426889272 0.7619987040334074 0.8568319508452604 1.20899574602486 1.0 15.250587848228498 -8.24713728369785 24.09607044519603 1.1044978689090248 0.8746268282131395 0.2854546796242562 0.1402839401092261 526.7629898886936 887492.2519646643 0.09511008526060638 0.035526965536678716 5.660603248984152e-09 8.24713728369785 -0.22987104069588526 TSDS(ph)TPDPQRVPLR ddPTM_PC-9_Lapatinib_30min_R1 1 TSDSTPDPQRVPLR 14 1 P52948-6;P52948-2;P52948-5;P52948;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 T(0.017)S(0.017)DS(0.483)T(0.483)PDPQRVPLR 69.729 0.0137 9397600.0 37627.0 28485.0 31498.0 28756.0 26704.0 22229.0 28312.0 22106.0 25508.0 31964.0 True False 37090.432080053295 28419.044732613173 28908.3560257961 30870.8121672039 25133.323222083996 21278.31748832991 29777.856828320088 23133.12546192062 22635.020428851938 37488.934810647224 0.9893701239417251 0.7580648763736516 0.7711170288462249 0.8234646389162353 0.6704197745022589 0.5675892792314456 0.7943105606687679 0.6170654242048665 0.6037787027873455 1.0 15.19417721383833 -1.5228787453171264 0.7528890095637917 0.7006362323828056 50.06737727627758 0.2707871406027672 0.12239148209052085 464.90678870776424 1.9824007385283449 0.043656883541283886 38939.603672047924 0.029999999997458716 1.5228787453171264 49.36674104389478 TSDST(ph)PDPQR ddPTM_PC-9_AZD4547_30min_R2 1 TSDSTPDPQR 10 0 P52948-6;P52948-2;P52948-5;P52948;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 T(0.002)S(0.002)DS(0.397)T(0.6)PDPQR 96.334 0.013621000000000001 7243600.0 13437.0 15751.0 12826.0 14297.0 12803.0 16101.0 14599.0 14731.0 14703.0 15275.0 True False 17709.686493037432 20842.20272240717 12655.918859640473 11001.04753644808 11025.524445866582 15094.201924705976 15898.282717989554 12454.66243470423 15480.170563230584 14740.226899348145 1.2014527736897052 1.4139675640494296 0.8585972893131077 0.74632823575698 0.7479887874964911 1.0240142182189533 1.0785643142774568 0.8449437393161846 1.050198933092079 1.0 13.847471111855219 -5.266224482938182 24.999745526791052 0.9104909149255871 1.3077101809892258 0.6142683494715113 0.123123281469861 240.51660379178634 1256583.4760493159 0.03407976085943556 0.07484590960949973 5.417208073754637e-06 5.266224482938182 0.39721926606363867 TSDST(ph)PDPQRVPLR ddPTM_PC-9_AZD4547_30min_R2 1 TSDSTPDPQRVPLR 14 1 P52948-6;P52948-2;P52948-5;P52948;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 T(0.005)S(0.005)DS(0.028)T(0.961)PDPQRVPLR 85.493 0.0049539 12720000.0 44809.0 33904.0 58344.0 88364.0 66736.0 53449.0 42526.0 64389.0 46459.0 52613.0 True False 59057.32991490021 44862.80497114424 57570.32043870759 67993.0450101909 57470.85834721178 50106.82558062291 46310.73161622191 54439.15956202367 48914.72789207165 50771.03488415084 1.1632091023879465 0.8836299097213998 1.1339205625820181 1.3392093575665176 1.1319615303952062 0.9869175543684797 0.9121486635419893 1.072248373235699 0.9634376766927264 1.0 15.631718046885368 -6.762380637700319 23.508184467445066 0.9867908239429344 1.1284750948360367 0.30135418329579466 0.10917905876870966 17.28455452110633 431669.2417192266 0.04046317714638096 0.03777062878997362 1.7283009246644038e-07 6.762380637700319 0.14168427089310232 TSDST(ph)PDPQRVPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSDSTPDPQRVPLR 14 1 P52948-6;P52948-2;P52948-5;P52948;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 T(0.019)S(0.035)DS(0.177)T(0.769)PDPQRVPLR 63.681999999999995 0.03141 8032600.0 24912.0 18898.0 26275.0 28942.0 33648.0 36631.0 37789.0 39898.0 31262.0 26140.0 True False 29129.109565571875 20774.068547468996 26901.495648492393 27320.47357123001 27054.915944189055 34710.00587480998 34209.35235133221 38850.719775425336 31719.147608106585 30878.97507587387 0.9433314899214648 0.6727577096203571 0.8711913391682119 0.8847597274229428 0.8761597778977904 1.1240659960223012 1.1078525847206762 1.2581609227626176 1.0272085627896748 1.0 14.914337247521594 -6.719685028664063 4.120009518416202 1.1217549995076341 0.8380497668740545 0.653659371765521 0.09200675290157041 0.1224378942788877 4.416633811043133 0.03120698908111251 0.03006258514367903 1.906843151358236e-07 6.719685028664063 -0.2837052326335796 TSDST(ph)PDPQRVPLR ddPTM_PC-9_Lapatinib_30min_R1 1 TSDSTPDPQRVPLR 14 1 P52948-6;P52948-2;P52948-5;P52948;H7C3P6 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 TSDS(0.047)T(0.953)PDPQRVPLR 105.19 0.010248 3090500.0 19846.0 13846.0 15038.0 13014.0 12807.0 13872.0 15088.0 11167.0 14342.0 11189.0 True False 19562.992400689327 13813.94043769571 13801.633688358692 13971.092973431336 12053.717439530772 13278.726897211402 15869.182813849005 11685.859587137767 12726.652932044633 13123.003741594652 1.4907404421963621 1.0526508038636815 1.0517130041358638 1.064626151796984 0.9185181744119548 1.0118664262148436 1.2092645194903107 0.8904866459877845 0.9697972493680128 1.0 13.679810357669817 -4.7561562009547265 4.34120014281913 1.017639823569258 1.537014015484854 0.7457801072157131 0.08291185307687961 0.11566727594504045 4.512770869157627 0.021209883158188444 0.19178416540540208 1.7532498041020244e-05 4.7561562009547265 0.5193741919155959 TSEIEPKNS(ph)PEDLGLSLTGDSCK ddPTM_PC-9_AZD4547_30min_R2 2 TSEIEPKNSPEDLGLSLTGDSCK 23 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 TSEIEPKNS(0.871)PEDLGLS(0.08)LT(0.031)GDS(0.018)CK;TSEIEPKNS(1)PEDLGLSLTGDSCK 85.932 1.5172e-05 47442000.0 79004.0 45424.0 72623.0 149648.0 131612.0 83090.0 67379.0 71403.0 65826.0 110447.0 True False 104125.62861471507 60106.4196852659 71659.97156897478 115148.96563855231 113339.94558848666 77894.3691648855 73375.6004695814 60369.30702770925 69305.42797355748 106580.2841474504 0.976968953006924 0.5639543951872994 0.6723567322248412 1.0803964969660564 1.0634231883983767 0.7308515809276803 0.688453789146111 0.5664209615372225 0.650264995331366 1.0 16.701581058937236 -6.978817735781076 24.98804033790355 0.6929388979330429 0.85911411359959 0.1214173812214504 0.1840461681409951 481.25261087616167 567716.6274836916 0.0687685237846882 0.060642857884101814 1.049982991877521e-07 6.978817735781076 0.16617521566654714 TSEIEPKNS(ph)PEDLGLSLTGDSCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSEIEPKNSPEDLGLSLTGDSCK 23 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 T(0.001)S(0.001)EIEPKNS(0.976)PEDLGLS(0.015)LT(0.006)GDS(0.001)CK;T(0.001)S(0.001)EIEPKNS(0.991)PEDLGLS(0.004)LT(0.001)GDS(0.002)CK;T(0.114)S(0.043)EIEPKNS(0.837)PEDLGLS(0.003)LT(0.002)GDSCK 62.06399999999999 0.0017605999999999998 27521200.0 93046.0 40763.5 50352.2 128507.0 111033.0 118103.0 100063.0 148532.0 119812.0 92541.0 True False 108796.85005773095 44810.23088341371 51552.78740978187 121307.16941531528 89276.88070705971 111909.47077155078 90584.30824661547 144633.19238266305 121564.02383796503 109317.9507458471 0.9952331645026199 0.4099073443810966 0.4715857465132762 1.1096729181956755 0.8166717368734728 1.0237062624026743 0.8286315982744188 1.3230507102984415 1.1120225270284179 1.0 16.738170795168763 -6.279451795030083 0.8948633617733742 1.0948165893976651 0.623565158320226 0.35398393625643765 0.21823122428814132 0.638840881174237 1.09679362984515 0.11156768508330214 0.17798149668515387 5.254703370025148e-07 6.279451795030083 -0.47125143107743916 TSEIEPKNS(ph)PEDLGLSLTGDSCK ddPTM_PC-9_Lapatinib_30min_R1 3 TSEIEPKNSPEDLGLSLTGDSCK 23 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 T(0.002)S(0.002)EIEPKNS(0.941)PEDLGLS(0.041)LT(0.014)GDS(0.001)CK;TSEIEPKNS(1)PEDLGLSLTGDSCK;TSEIEPKNS(0.932)PEDLGLS(0.056)LT(0.011)GDS(0.001)CK 106.36 1.0111e-06 51154300.0 234876.0 119844.0 134080.0 145264.0 124377.0 123855.0 88847.0 89853.0 130049.0 95452.0 True False 231526.62516901648 119566.50858119367 123056.45996376757 155947.1991464988 117061.38939459043 118558.01037010664 93447.06292829015 94027.89840450343 115401.51214331844 111950.75101820455 2.0681114066967488 1.0680277487531165 1.0992017368758615 1.3929982401023813 1.0456507734865916 1.0590193392345146 0.8347158199331286 0.8399041323913348 1.0308239211772037 1.0 16.77250468093554 -2.9705934409421038 1.4663697606305799 1.0249167969063167 199.99999999989407 0.8001993030897124 0.15239240607573562 126.90532501381621 1.880166894458256 0.04773388452373029 83535.07197473604 0.001070056129444738 2.9705934409421038 198.97508320298775 up TSELLSGMGVSALEKEEPDSENIPQELLS(ph)NLGHPESPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSELLSGMGVSALEKEEPDSENIPQELLSNLGHPESPPR 39 1 D6R9R7;A0A0A0MTL5;Q13309-2;Q13309;D6RF40;D6RAG5 D6R9R7 SKP2 S-phase kinase-associated protein 2 1 TSELLSGMGVSALEKEEPDS(0.001)ENIPQELLS(0.499)NLGHPES(0.499)PPR 73.23899999999999 1.3607e-07 15609000.0 15087.0 11450.0 16929.0 27899.0 30539.0 28011.0 23748.0 29524.0 27312.0 17689.0 True False 17640.93111816725 12586.6803295862 17332.651563590025 26335.909479778387 24555.1021760458 26542.053849452688 21498.417519369043 28749.026283263778 27711.386330772388 20895.87567395305 0.844230287039699 0.6023523745059242 0.8294771577912561 1.2603400733574617 1.1751171647070056 1.2702053871108 1.028835443645325 1.375822996453782 1.3261653525874941 1.0 14.350930597841177 -5.67690738843646 4.400044061309781 1.2153006438902034 0.7227855019712943 0.7285575202758803 0.12553927168062784 0.0994233027457882 3.5094383777513083 0.03368342109701216 0.059586325771370845 2.104227109952383e-06 5.67690738843646 -0.4925151419189091 TSELLSGMGVSALEKEEPDSENIPQELLSNLGHPES(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 2 TSELLSGMGVSALEKEEPDSENIPQELLSNLGHPESPPR 39 1 D6R9R7;A0A0A0MTL5;Q13309-2;Q13309;D6RF40;D6RAG5 D6R9R7 SKP2 S-phase kinase-associated protein 2 1 TSELLSGMGVSALEKEEPDSENIPQELLS(0.006)NLGHPES(0.994)PPR;TSELLSGMGVSALEKEEPDSENIPQELLS(0.249)NLGHPES(0.751)PPR 78.083 9.7378e-10 37162000.0 24766.0 19169.7 35466.0 59805.0 45465.0 43117.0 32006.0 38657.0 35995.0 45434.0 True False 32641.072835198724 25365.93064108494 34995.69766692726 46017.88122803931 39152.96953302539 40420.88717393625 34854.47199616231 32683.448899488245 37897.62221475108 43843.36948903332 0.7444927982408682 0.5785579652455726 0.7981981785337198 1.049597276950849 0.8930191723247649 0.921938428661302 0.7949770376312106 0.745459331260191 0.8643866257640287 1.0 15.420071057371553 -5.515857674922851 24.928350563026815 0.8850508893877863 0.6682385180516025 0.5077578184546417 0.09143108127871794 252.52145618784158 896577.336929179 0.025765926147387503 0.046999239017279294 3.0488939960523534e-06 5.515857674922851 -0.2168123713361838 TSELLSGMGVSALEKEEPDSENIPQELLSNLGHPES(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 1 TSELLSGMGVSALEKEEPDSENIPQELLSNLGHPESPPR 39 1 D6R9R7;A0A0A0MTL5;Q13309-2;Q13309;D6RF40;D6RAG5 D6R9R7 SKP2 S-phase kinase-associated protein 2 1 TSELLSGMGVSALEKEEPDSENIPQELLS(0.2)NLGHPES(0.8)PPR 78.747 8.6328e-10 12052000.0 13098.0 9479.0 16779.0 14756.0 14750.0 14234.0 9947.3 9793.3 17674.0 10972.0 True False 12911.22011812098 9457.051957888023 15399.495388813028 15841.205464573002 13882.433999615743 13625.245001074618 10462.322521487298 10248.332470199364 15683.368004529135 12868.495580728975 1.003320087971743 0.734899576921042 1.1966818725783543 1.2310067921455998 1.0787923042383585 1.058806362841582 0.813018309393912 0.7963893219613489 1.2187413754887968 1.0 13.65155578158627 TSELLSGMGVSALEKEEPDSENIPQELLSNLGHPESPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSELLSGMGVSALEKEEPDSENIPQELLSNLGHPESPPR 39 1 D6R9R7;A0A0A0MTL5;Q13309-2;Q13309;D6RF40;D6RAG5 D6R9R7 SKP2 S-phase kinase-associated protein 2 0 59.386 6.5326e-05 1599700.0 1797.8 1806.6 2309.9 5807.9 5458.6 5951.7 3393.2 6039.6 4970.5 2588.0 False True 2102.132031831451 1985.9473085965433 2364.9767763445334 5482.502192465855 4389.026514887967 5639.582374630957 3071.7715313594013 5881.066899485158 5043.184159237852 3057.1839134032725 0.687604047180579 0.6496002088359076 0.7735801454325426 1.793317755084844 1.4356435985567124 1.8446984330599023 1.0047715866527276 1.9236876374042948 1.6496175245223486 1.0 11.577987628831305 -5.704913145575377 7.080052298067204 1.547910960137999 0.6885180718008721 0.6052032767114119 0.3024058001743256 0.1341159485213217 13.525984538336095 0.07794279734340784 0.13485532721283103 1.9728172397998464e-06 5.704913145575377 -0.8593928883371269 TSELLSGMGVSALEKEEPDSENIPQELLSNLGHPESPPR ddPTM_PC-9_Lapatinib_30min_R1 1 TSELLSGMGVSALEKEEPDSENIPQELLSNLGHPESPPR 39 1 D6R9R7;A0A0A0MTL5;Q13309-2;Q13309;D6RF40;D6RAG5 D6R9R7 SKP2 S-phase kinase-associated protein 2 0 66.173 1.9787000000000002e-06 2158700.0 2163.2 2285.1 3569.3 3497.6 3899.9 3365.8 3548.6 2241.8 3346.2 2501.5 False True 2132.352371317704 2279.8089913461263 3275.8459318964397 3754.8251716515642 3670.5155494984065 3221.8525800630146 3732.3291445668474 2345.9622120932613 2969.315718951873 2933.88094196077 0.7268026254305369 0.7770625449519725 1.116557214386187 1.2798151138137668 1.2510785618469333 1.0981538255297392 1.2721474451081367 0.7996105699249707 1.0120777828726142 1.0 11.518594611730697 -5.24220927981739 5.377846603289144 1.114552047603875 0.7449837443618297 0.5037796653242617 0.13949676925867832 0.14623253356929933 13.935527458615434 0.03890392030182323 0.09996841976999153 5.725200759011434e-06 5.24220927981739 -0.36956830324204537 TSET(ph)SISPPGSSIGSPNR ddPTM_PC-9_AZD4547_30min_R2 1 TSETSISPPGSSIGSPNR 18 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 TSET(0.937)S(0.06)IS(0.003)PPGSSIGSPNR 207.21 7.1928e-20 33806000.0 7777.9 8910.7 13351.0 16103.0 13263.0 14853.0 13560.0 14432.0 12578.0 11748.0 True False 10251.110409629817 11790.909516764246 13173.957016611572 12390.70213886994 11421.66138604455 13924.239561993534 14766.813730799244 12201.866014367748 13242.847401504065 11336.7060958129 0.9042406430044052 1.0400648492703803 1.162062146206405 1.092971982703717 1.0074938248829637 1.2282438518130336 1.3025665132355526 1.0763149288023253 1.1681389011571164 1.0 13.468713902586616 -4.858980848214898 2.1749110631074995 1.136958233042824 0.8630123825547549 0.37799091194725165 0.08888760331324434 0.5766561468732639 3.635601332205327 0.02454111546246644 0.2933465469789875 1.3836273936780099e-05 4.858980848214898 -0.2739458504880692 TSETLS(ph)QAGQK ddPTM_PC-9_Lapatinib_30min_R1 1 TSETLSQAGQK 11 0 H0YC42;P55327-2;P55327;P55327-3;P55327-4;P55327-7;P55327-5;P55327-6 H0YC42 TPD52 Tumor protein D52 1 TSET(0.02)LS(0.98)QAGQK 88.552 0.0097653 7722400.0 16453.0 14616.0 14431.0 10419.0 9272.3 10977.0 14959.0 11913.0 12638.0 8920.4 True False 16218.377202889325 14582.157550004364 13244.53888527093 11185.248016765117 8726.921544043196 10507.539298636797 15733.503825050857 12466.521470544665 11214.575355960122 10462.279254314146 1.5501762865105746 1.393784011642719 1.2659324572902708 1.0691024149592312 0.8341319641649433 1.004326021435911 1.5038313777146703 1.191568411386464 1.0719055650646836 1.0 13.35290956294003 -5.27805829102289 1.9556751199041338 1.109020579878169 1.5268221649500702 0.45702252491614603 0.1649781764690529 0.4003955374911471 2.7537079557626822 0.05214743324326156 0.20540311143135634 5.271591013583583e-06 5.27805829102289 0.41780158507190124 TSETS(ph)ISPPGSSIGSPNR ddPTM_PC-9_AZD4547_30min_R2 1 TSETSISPPGSSIGSPNR 18 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 TSET(0.032)S(0.955)IS(0.013)PPGSSIGSPNR 218.28 1.1394999999999998e-27 31145000.0 19084.0 15414.0 24029.0 40000.0 29973.0 27374.0 23953.0 27555.0 24960.0 27413.0 True False 25152.315028140667 20396.27406280136 23710.35975973031 30778.617993839496 25811.766321640145 25662.299452636562 26084.77059689046 23297.007900907945 26279.334643150065 26453.279213867827 0.9508203056713987 0.7710300828076108 0.8963107964059301 1.1635086049257803 0.9757492110130763 0.9700989901918624 0.9860694542253884 0.8806850641297718 0.9934244609406847 1.0 14.69115895301713 -5.537026455975282 24.995615163931205 0.9915780648199799 0.8541114497577312 0.35447449349240356 0.07676527261148904 230.11338949562312 406553.7930500686 0.020963313263884484 0.036329751492188235 2.9038457551145368e-06 5.537026455975282 -0.13746661506224866 TSETSIS(ph)PPGSSIGSPNR ddPTM_PC-9_AZD4547_30min_R2 2 TSETSISPPGSSIGSPNR 18 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 TSETS(0.001)IS(0.954)PPGS(0.035)S(0.009)IGSPNR;TSETS(0.001)IS(0.938)PPGS(0.05)S(0.01)IGSPNR 124.46 4.4905e-05 27428000.0 20066.7 16671.2 31815.0 41933.0 31717.0 37145.0 33234.0 30475.0 23026.0 27921.0 True False 26447.493186710883 22059.83937691541 31393.112312448276 32265.994708391798 27313.642025271438 34822.317278007795 36191.76161721107 25765.788995832674 24243.107351489325 26943.49428849096 0.981591062522579 0.8187445600305219 1.1651462863841677 1.1975430641219527 1.013737926225055 1.2924202371509885 1.3432467678355495 0.9562898085879918 0.8997759196306204 1.0 14.71764934489192 -5.267490850084712 24.851202391913713 1.1217042121032565 0.9001678083430013 0.25184368662983914 0.14219917193713072 551.2457705149483 2263775.378589619 0.039273414708725356 0.08523468067416821 5.401434946355805e-06 5.267490850084712 -0.2215364037602553 TSETSIS(ph)PPGSSIGSPNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TSETSISPPGSSIGSPNR 18 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 TSETSIS(0.825)PPGS(0.071)S(0.102)IGS(0.001)PNR;T(0.004)S(0.003)ET(0.013)S(0.01)IS(0.966)PPGS(0.003)S(0.001)IGSPNR;TSETS(0.002)IS(0.938)PPGS(0.045)S(0.014)IGSPNR;TSET(0.006)S(0.006)IS(0.987)PPGS(0.001)SIGSPNR 249.86 7.852499999999999e-54 65356000.0 24494.600000000002 27165.8 34754.0 39195.5 41536.3 40761.399999999994 37684.7 30275.399999999998 35245.1 27776.9 True False 28641.051989597643 29862.641091482332 35582.66716527896 36999.50320852554 33397.56018582441 38623.80042765633 34114.932402398816 29480.702829437858 35760.492910321685 32812.632088180595 0.8728666421098967 0.9100958743946397 1.0844197767998063 1.1275993681059524 1.0178263083580703 1.177101560272849 1.0396889926635091 0.8984558980276707 1.0898392062611442 1.0 15.001963704837044 -5.187451606298566 4.984751127598453 1.0558315245200005 0.8843130798648066 0.45175147810941696 0.07199648267033366 0.1996013832563416 9.146560217645598 0.019233663584736063 0.05387569477440081 6.494539966028876e-06 5.187451606298566 -0.17151844465519395 TSETSIS(ph)PPGSSIGSPNR ddPTM_PC-9_Lapatinib_30min_R1 1 TSETSISPPGSSIGSPNR 18 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 1 T(0.001)SET(0.219)S(0.021)IS(0.751)PPGS(0.006)S(0.001)IGSPNR 249.89 7.767300000000001e-54 31571000.0 23076.0 21614.0 22587.0 20957.0 23658.0 22996.0 18888.0 16082.0 20403.0 12729.0 True False 22746.93200837988 21563.954110960207 20729.984048341375 22498.247690502583 22266.48295341758 22012.514686294235 19865.928220306218 16829.228430227427 18104.999286885137 14929.190689673636 1.523654729932125 1.4444154783203196 1.388553772220224 1.506997141249216 1.4914728746025778 1.4744613518480985 1.330676835285336 1.1272699759852371 1.2127247660791267 1.0 13.865848338749885 -7.614111456929124 2.0142572897904536 1.1093857348939251 1.4709086925790698 0.8788341794500897 0.05948515739246021 0.11002715842561443 0.8849663361542597 0.03745192201071708 0.017688674365624234 2.431579890604671e-08 7.614111456929124 0.36152295768514464 TSFLDDAFR ddPTM_PC-9_Lapatinib_30min_R1 1 TSFLDDAFR 9 0 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2;A0A2R8Y5T0;A0A2R8Y542;H0YJ21 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 91.853 0.022205000000000003 0.0 13298.0 13702.0 12455.0 11133.0 13189.0 12000.0 11954.0 14051.0 15550.0 9846.1 False True 13108.36808144546 13670.273860848369 11430.997977690342 11951.757958599293 12413.248950571675 11486.787973366268 12572.919628628777 14703.860755697395 13798.59525124069 11547.985265896437 1.1351216493284895 1.1837799881178828 0.9898694633295401 1.0349647738030356 1.074927674806664 0.9947006087104304 1.0887543878116281 1.2732836436084574 1.1948920035420172 1.0 13.49535355149891 -7.547888270120929 24.218236210094254 1.1766566311934457 1.06696204729944 0.16366009157567107 0.08451112060945615 226.2771115779129 219113.98923283193 0.039746858152536826 0.022949306548811676 2.8321205148006625e-08 7.547888270120929 -0.10969458389400555 TSFNYAMK ddPTM_PC-9_Lapatinib_30min_R1 2 TSFNYAMK 8 0 B4DLR8;P15559-3;P15559-2;P15559;H3BRK3 B4DLR8 NQO1 NAD(P)H dehydrogenase [quinone] 1 0 ; 100.02 0.023138 10186700.0 57354.0 43600.0 45835.0 50156.0 54298.0 45325.0 46581.0 38274.0 49688.0 41833.0 False True 56536.12144256452 43499.046878776 42066.62322821656 53844.63955551117 51104.29839397531 43386.55540773549 48992.736257416516 40052.34976610647 44091.61420216381 49063.7783110313 1.1522985670643544 0.8865816774856055 0.8573865420951176 1.0974417667993774 1.041589134656701 0.8842889174309805 0.9985520468243512 0.8163323564728658 0.8986591681270993 1.0 15.582370717005881 -7.7328605229842085 24.990553664842533 0.8931217214926438 0.9816040222497431 0.12403599292357537 0.09885351490169962 404.47506314652617 353690.32173580053 0.04671227796188663 0.026962896021247407 1.8498626212086693e-08 7.7328605229842085 0.08848230075709929 TSFS(ph)VGSDDELGPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSFSVGSDDELGPIR 15 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 T(0.001)S(0.015)FS(0.644)VGS(0.34)DDELGPIR;T(0.01)S(0.037)FS(0.476)VGS(0.476)DDELGPIR 236.05 6.1836e-32 11450000.0 32439.8 41265.0 43343.9 42649.0 59459.8 50318.3 45523.7 44032.0 36323.68 37496.2 True False 37931.21742474461 45361.51648911568 44377.38295865614 40259.51479992359 47809.07902574574 47679.51976769538 41211.36557295357 42876.206655760405 36854.8451023488 44293.964240244124 0.8563518320241357 1.0241015286661024 1.0018832976420797 0.9089164966486573 1.079358775982121 1.076433789242446 0.9304058979555097 0.967992081792589 0.8320511775025011 1.0 15.434822501491672 -7.441508787081599 24.997217032040563 0.9298467270081416 0.994259994126226 0.12465212105724066 0.07562120153691303 197.0874832802781 60544.42931709794 0.03169257949336246 0.021367121904725152 3.6181886997605166e-08 7.441508787081599 0.06441326711808437 TSFS(ph)VGSDDELGPIR ddPTM_PC-9_Lapatinib_30min_R1 2 TSFSVGSDDELGPIR 15 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 T(0.001)SFS(0.662)VGS(0.337)DDELGPIR;T(0.013)S(0.009)FS(0.781)VGS(0.197)DDELGPIR 244.23 4.54e-40 16961200.0 64665.7 64288.9 66579.4 60239.2 68381.2 55953.0 54454.8 55566.9 66088.5 52400.0 True False 63743.55525976295 64140.04300194823 61105.498735916284 64669.39172008032 64359.152258611895 53560.02062281354 57274.203094617245 58148.74103094168 58644.91718724253 61457.27018138889 1.0372012143010285 1.0436526518773326 0.9942761622110067 1.052265932561127 1.0472178811173716 0.8715001571780376 0.9319353581044931 0.9461653740772701 0.9542388884855151 1.0 15.907296066050169 -6.740586890171886 24.999373485261707 0.936851244720446 1.034113153902746 0.6703262817220867 0.032955384527783786 138.85389465882102 166467.1288216647 0.010742154383106198 0.010731114351206432 1.8172434401660933e-07 6.740586890171886 0.09726190918229993 TSFSQEQSCDS(ph)AGEGSER ddPTM_PC-9_AZD4547_30min_R2 1 TSFSQEQSCDSAGEGSER 18 0 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 TSFSQEQSCDS(0.999)AGEGSER 287.38 7.1537e-106 5467400.0 6288.6 7321.0 9104.0 16241.0 12122.0 11496.0 8993.7 11302.0 9567.3 9212.0 True False 8288.243988994214 9687.370080042085 8983.275011552072 12496.88837094868 10439.069540950919 10777.153302678087 9794.121876894484 9555.535594123088 10073.007945969932 8889.490683914573 0.9323643258878366 1.0897553554526205 1.0105500226022173 1.405804766021258 1.1743158198973414 1.2123476682617167 1.1017641195818821 1.0749249798319396 1.1331366783697652 1.0 13.11788504805461 -4.903013752911566 1.6118136686074738 1.1559810757503757 0.8979016028374749 0.2444116062041719 0.10918563932421221 1.118322097914343 3.398201791766508 0.03143735212426719 0.4250874678778262 1.2502194385803828e-05 4.903013752911566 -0.2580794729129008 TSFSQEQSCDS(ph)AGEGSER ddPTM_PC-9_Lapatinib_30min_R1 3 TSFSQEQSCDSAGEGSER 18 0 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 TSFSQEQS(0.011)CDS(0.536)AGEGS(0.453)ER;TSFSQEQSCDS(1)AGEGSER;TSFSQEQSCDS(1)AGEGSER 326.94 6.470499999999998e-177 20044100.0 27116.2 32031.2 38909.5 31672.4 34106.7 30083.3 30455.1 30770.4 35903.9 27790.2 True False 26729.518015497946 31957.03372439108 35710.511105013466 34001.69395202912 32100.61096235217 28796.707386597456 32031.916060051222 32200.105116867908 31860.024697171768 32593.699041886113 0.8200823717844324 0.9804666136029281 1.0956262147208864 1.0431983773407736 0.9848716747706274 0.8835053471405885 0.9827640618171952 0.9879242327017747 0.977490301307271 1.0 14.992305471624402 -4.767233570812003 5.4974846008255716 0.9939056422285153 0.8123337814638139 0.5141264477391294 0.05053214663203349 0.13174195010897372 12.600789602238613 0.014066182220678692 0.09048760351245068 1.7090958876119616e-05 4.767233570812003 -0.18157186076470144 TSFSVGS(ph)DDELGPIR ddPTM_PC-9_AZD4547_30min_R2 8 TSFSVGSDDELGPIR 15 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 TSFS(0.001)VGS(0.999)DDELGPIR;TSFSVGS(1)DDELGPIR;T(0.007)SFS(0.002)VGS(0.992)DDELGPIR;TSFSVGS(1)DDELGPIR;TSFS(0.013)VGS(0.987)DDELGPIR;TSFS(0.002)VGS(0.998)DDELGPIR;TS(0.002)FS(0.073)VGS(0.925)DDELGPIR;T(0.001)SFS(0.008)VGS(0.99)DDELGPIR 230.67 7.6471e-25 51405000.0 120833.40000000001 114114.3 154043.3 220809.0 187785.7 153728.90000000002 128007.99999999999 175308.2 141075.5 157832.0 True False 159255.90770914545 150999.51584823744 152000.58519189575 169904.8965150429 161714.8969721286 144116.20758107785 139400.46401564538 148218.34587167288 148532.46291865857 152306.34972032218 1.0456288132542382 0.9914197019724755 0.997992437419793 1.115547032852121 1.061773834571462 0.9462258654725574 0.9152636398392078 0.9731593340910866 0.9752217369230269 1.0 17.2166165641219 -6.765351753422322 24.988458285103064 0.9573771582161521 1.041224705483936 0.5242688788970913 0.038206225446427974 86.55086315957415 552799.8781623911 0.014348841290579726 0.013120318027627172 1.7165175440093372e-07 6.765351753422322 0.08384754726778398 TSFSVGS(ph)DDELGPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 TSFSVGSDDELGPIR 15 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 T(0.071)S(0.001)FS(0.113)VGS(0.815)DDELGPIR;TSFSVGS(1)DDELGPIR;TSFSVGS(1)DDELGPIR;TSFSVGS(1)DDELGPIR;TSFS(0.059)VGS(0.941)DDELGPIR;TSFS(0.012)VGS(0.988)DDELGPIR;TSFS(0.003)VGS(0.997)DDELGPIR 252.52 1.5647e-77 22606400.0 74706.7 78020.90000000001 83954.90000000001 100701.30000000002 106956.1 84450.09999999999 90989.90000000001 86435.7 79237.9 70659.0 True False 87353.06878541676 85766.29932983502 85956.70321673121 95059.33263901937 85998.81999578809 80021.38809009545 82370.67796217118 84166.85446119426 80396.60438412074 83468.91736366367 1.046534105681883 1.02752380213777 1.0298049373544473 1.1388590584547504 1.0303095177466115 0.9586968492888466 0.9868425344885258 1.0083616407109939 0.9631921309562788 1.0 16.3489514380503 -6.549913219451747 8.01727827125366 0.9850880588338901 1.059624904499732 0.5647870668190444 0.032116871925974545 0.16330321201530115 40.01874523691899 0.010936700507004151 0.011030563252204351 2.818946155675086e-07 6.549913219451747 0.07453684566584184 TSFSVGS(ph)DDELGPIR ddPTM_PC-9_Lapatinib_30min_R1 8 TSFSVGSDDELGPIR 15 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 TSFSVGS(1)DDELGPIR;TSFS(0.001)VGS(0.999)DDELGPIR;TSFSVGS(0.999)DDELGPIR;T(0.001)S(0.002)FS(0.181)VGS(0.816)DDELGPIR;TSFS(0.007)VGS(0.993)DDELGPIR;TSFS(0.148)VGS(0.852)DDELGPIR;TS(0.001)FS(0.026)VGS(0.973)DDELGPIR;TSFS(0.008)VGS(0.992)DDELGPIR 274.38 7.455599999999999e-75 21069500.0 130724.7 124138.90000000001 130923.2 112416.0 108744.5 120122.7 99431.8 105407.5 134006.7 91679.8 True False 128860.54180602623 123851.46400412101 120159.1998741671 120683.44764878244 102348.3623099129 114985.33214069047 104579.89208046599 110305.11725899759 118913.45429288992 107526.5312743451 1.1984069445823482 1.1518223691985765 1.1174842008768122 1.1223597210707796 0.9518428716795436 1.0693670741346137 0.9725961661837578 1.0258409338767114 1.1058987292121607 1.0 16.714333151138334 -6.08917658952021 5.4745504993710155 1.022375895875491 1.1504012263977923 0.6548432786373866 0.045409978435457236 0.14297468409659086 6.787635303719999 0.013434740895636172 0.017636601234563506 8.143730824991049e-07 6.08917658952021 0.12802533052230136 TSFSVGS(ph)DDELGPIRK ddPTM_PC-9_Lapatinib_30min_R1 1 TSFSVGSDDELGPIRK 16 1 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 T(0.157)S(0.177)FS(0.152)VGS(0.514)DDELGPIRK 56.121 0.028807999999999997 3046500.0 15308.0 15610.0 17468.0 13867.0 12312.0 12815.0 10871.0 11924.0 15911.0 13490.0 True False 15089.70511285662 15573.85600407555 16031.848468429953 14886.82543895592 11587.832366323324 12266.93232322406 11433.847187788482 12478.032570702138 14118.93562974217 15821.728525704886 0.9537330316558662 0.9843334107757803 1.0132804669466862 0.9409101802480008 0.7323998985001587 0.7753218811266102 0.7226673855016789 0.788664307469921 0.8923763043212212 1.0 13.949619602573623 -6.110067164156886 5.148761619107494 0.8016707645800668 0.9829121402493237 0.48004764150397905 0.07839095283000577 0.17258457200528124 6.7367670162704965 0.022721023136754715 0.02981779262673485 7.76127078373411e-07 6.110067164156886 0.1812413756692569 TSGAPGS(ph)PQTPPER ddPTM_PC-9_AZD4547_30min_R2 2 TSGAPGSPQTPPER 14 0 K7ESM2;K7ELS4;K7EJA3;K7ERG7;Q96MH2;K7EIM4 K7ESM2 HEXIM2 Protein HEXIM2 1 T(0.013)S(0.001)GAPGS(0.972)PQT(0.013)PPER;T(0.002)S(0.001)GAPGS(0.954)PQT(0.043)PPER 147.7 1.9376e-05 31558000.0 48024.0 52785.0 54169.0 66043.0 62332.0 64562.0 56367.0 69885.0 52648.0 57907.0 True False 63294.63303874596 69846.71898306538 53450.683666604185 50817.806704178576 53678.27772863826 60524.92793384677 61383.55380265203 59085.87904753951 55430.86579697777 55879.69355551904 1.1326947055616874 1.2499481392765595 0.9565314386253474 0.9094145559994661 0.9606043682989497 1.0831292028062478 1.0984948180087037 1.057376576140937 0.9919679631368175 1.0 15.77003648857268 -5.262417588052412 24.99793756066304 1.0100562946208587 1.1913214278770219 0.586865649790745 0.061759134260645374 63.6111652192447 1625621.9247763294 0.018093433302804027 0.0415507616500351 5.464902423168278e-06 5.262417588052412 0.18126513325616322 TSGAPGS(ph)PQTPPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSGAPGSPQTPPER 14 0 K7ESM2;K7ELS4;K7EJA3;K7ERG7;Q96MH2;K7EIM4 K7ESM2 HEXIM2 Protein HEXIM2 1 T(0.006)SGAPGS(0.97)PQT(0.024)PPER;T(0.008)S(0.001)GAPGS(0.667)PQT(0.325)PPER;TSGAPGS(0.939)PQT(0.061)PPER 118.51 0.0015427 12717000.0 39962.5 49619.0 46321.0 47394.0 61807.0 49469.0 54242.0 41719.0 40684.8 38742.3 True False 46727.36195464695 54544.84639945308 47425.46831337077 44738.667833421125 49696.36203526189 46874.758554802596 49103.80508192759 40623.92045493432 41279.73823192037 45765.97230612197 1.0210066475173822 1.1918209895030853 1.0362604774601678 0.9775530941235258 1.085880175403029 1.024227306726144 1.0729326311146485 0.887644649680046 0.9019744616328955 1.0 15.481987710822366 -7.756393944544882 24.99984913158186 0.9211071548669715 1.0594148593619523 0.4890007430337753 0.06006267408511245 97.07067743607521 480987.2650225634 0.029495934924599496 0.016349057680596538 1.7522902942506067e-08 7.756393944544882 0.13830770449498087 TSGAPGS(ph)PQTPPER ddPTM_PC-9_Lapatinib_30min_R1 2 TSGAPGSPQTPPER 14 0 K7ESM2;K7ELS4;K7EJA3;K7ERG7;Q96MH2;K7EIM4 K7ESM2 HEXIM2 Protein HEXIM2 1 TSGAPGS(0.901)PQT(0.099)PPER;TSGAPGS(0.5)PQT(0.5)PPER 158.29 0.00012828 32298000.0 30898.0 35709.0 36462.0 36630.0 42723.0 36267.0 36648.0 35893.0 39247.0 36995.0 True False 30457.388854000747 35626.318004454435 33464.23510739023 39323.89239409789 40210.117136649766 34715.9449525062 38545.45411995881 37560.71981383862 34826.58957076808 43389.5364572611 0.7019523908489186 0.821080862192352 0.7712512702308462 0.9062989744735372 0.9267238237554559 0.8000994660706175 0.8883582832908636 0.8656630810249866 0.8026494960385769 1.0 15.405059553065643 -1.5228787454725268 0.0358796220859953 1.393555948329876 4.606177041933851e-07 0.4678171281371366 0.059684046872691174 966.1118400515179 2.657636877290076 30.13738735028708 86.59754882923545 0.02999999998672404 1.5228787454725268 -1.3935554877121719 TSGAPGSPQT(ph)PPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSGAPGSPQTPPER 14 0 K7ESM2;K7ELS4;K7EJA3;K7ERG7;Q96MH2;K7EIM4 K7ESM2 HEXIM2 Protein HEXIM2 1 T(0.017)SGAPGS(0.079)PQT(0.904)PPER 142.19 0.00035719 15066000.0 55017.0 63048.0 54756.0 78099.0 82231.0 59829.0 65492.0 52314.0 56696.0 50357.0 True False 64330.29146471847 69306.98877028383 56061.590703286405 73723.36623037427 66118.4258501725 56691.46191706491 59288.12363898089 50940.812931264736 57525.071741705935 59486.325474207355 1.0814299076619116 1.1650911065322838 0.9424282010425089 1.239333000360561 1.1114894948224825 0.9530167053543378 0.9966681109709423 0.856344925076136 0.9670301751391284 1.0 15.860270443971743 -6.766324470460934 8.452805888493286 0.948032433110616 1.1093719327440055 0.4837362937984728 0.0790583798823546 0.102173737122644 64.40969472178732 0.026663492620502324 0.024755210199317566 1.7126772525114657e-07 6.766324470460934 0.16133949963338945 TSGGDHAPDS(ph)PSGENSPAPQGR ddPTM_PC-9_AZD4547_30min_R2 1 TSGGDHAPDSPSGENSPAPQGR 22 0 E9PL60;E9PII7;H0YDE3;H0YDU2;E9PRI1;Q96NY9 E9PL60 MUS81 Crossover junction endonuclease MUS81 1 T(0.001)S(0.001)GGDHAPDS(0.74)PS(0.249)GENS(0.009)PAPQGR 54.3 0.0081625 5299300.0 4329.5 4667.4 10995.0 18033.0 12004.0 12563.0 7766.3 13695.0 9859.5 10356.0 True False 5706.1909408056545 6176.045774018363 10849.199115994625 13875.77045707269 10337.45180412266 11777.43362400355 8457.48565468335 11578.752429792565 10380.65304143181 9993.439592121078 0.5709936892303296 0.6180100171804326 1.0856321305577548 1.388487950436252 1.0344238046200633 1.1785165173049117 0.8463037752638554 1.1586353550304505 1.0387467643889112 1.0 13.286765602161877 -5.255391519436001 5.624581388302939 1.101037583882998 0.5876744751493875 0.6920541906724658 0.1325938894119558 0.08367110324048829 10.418025507486737 0.03478628791576212 0.08572262924859542 5.554033316207704e-06 5.255391519436001 -0.5133631087336105 TSGGDHAPDS(ph)PSGENSPAPQGR ddPTM_PC-9_Lapatinib_30min_R1 1 TSGGDHAPDSPSGENSPAPQGR 22 0 E9PL60;E9PII7;H0YDE3;H0YDU2;E9PRI1;Q96NY9 E9PL60 MUS81 Crossover junction endonuclease MUS81 1 T(0.001)S(0.001)GGDHAPDS(0.575)PS(0.361)GENS(0.063)PAPQGR 80.664 0.00027352 4793300.0 21632.0 16625.0 32533.0 19849.0 28976.0 35988.0 20938.0 24048.0 30870.0 18636.0 True False 21323.523713177034 16586.505833936946 29858.262321011633 21308.761674322937 27271.688649007865 34448.87713212544 22022.06718957918 25165.357871540164 27393.095524488755 21857.207769090903 0.975583154922992 0.7588574903603444 1.366060232233109 0.9749077695302167 1.2477206117596495 1.5760877371006596 1.007542565465357 1.1513528231692722 1.253275158194102 1.0 14.41582148984645 -5.255748266446903 24.99877721416116 1.2031590081550783 0.867220309090195 0.34646305574209346 0.1810847740470491 495.9750618834978 2178603.312528082 0.045877473712565786 0.11462529307121078 5.549472882459143e-06 5.255748266446903 -0.3359386990648833 TSGGDHAPDSPS(ph)GENSPAPQGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSGGDHAPDSPSGENSPAPQGR 22 0 E9PL60;E9PII7;H0YDE3;H0YDU2;E9PRI1;Q96NY9 E9PL60 MUS81 Crossover junction endonuclease MUS81 1 TSGGDHAPDS(0.166)PS(0.813)GENS(0.021)PAPQGR 93.5 0.00010662 5157700.0 7600.9 8269.0 16140.0 11255.0 18848.0 14873.0 13770.0 14434.0 14115.0 11256.0 True False 8887.582245381944 9089.891672082813 16524.83881129086 10624.418839202322 15154.86970150009 14093.033697579885 12465.605913833246 14055.122794087161 14321.405172043515 13296.623697553036 0.6684089470786119 0.6836240446328955 1.2427845735253764 0.7990313241065492 1.1397532220370368 1.0598956560809805 0.9375015941924625 1.057044488419546 1.077070803671692 1.0 13.698772340075331 -5.235324147981662 23.451943677876447 1.033302525432542 0.6760161144383642 0.6301046254038958 0.11121449968639739 205.90224408912331 184901.96499651045 0.026345056088565494 0.06963247834633102 5.816689106535239e-06 5.235324147981662 -0.3572864109941779 TSGPLS(ph)PPTGPPGPAPAGPAVR ddPTM_PC-9_AZD4547_30min_R2 2 TSGPLSPPTGPPGPAPAGPAVR 22 0 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;A0A2R8YHA2 P49815 TSC2 Tuberin 1 TS(0.001)GPLS(0.993)PPT(0.007)GPPGPAPAGPAVR;TSGPLS(1)PPTGPPGPAPAGPAVR 151.63 1.5908e-05 8642900.0 30732.0 30404.0 35493.0 42806.0 32804.0 40827.0 30746.0 44001.0 33530.0 31994.0 True False 40504.13673468975 40231.49841737461 35022.339629285765 32937.73804610735 28249.730838257234 38274.081235946265 33482.33443710573 37201.65649239162 35302.32734714832 30873.899798215676 1.3119216230996074 1.30309091758145 1.1343672117284596 1.0668473455371825 0.9150036445959411 1.2396905310341868 1.0844867236059634 1.204954888612473 1.1434359629938482 1.0 14.91410010624064 -5.297056897041763 3.73166636599863 1.1003947867086825 1.3127722560439874 0.4756244603174773 0.08839569822583786 0.1960564229614508 5.848942276640864 0.024137980125791873 0.06051935901076851 5.0459518607626565e-06 5.297056897041763 0.21237746933530488 TSGPLS(ph)PPTGPPGPAPAGPAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSGPLSPPTGPPGPAPAGPAVR 22 0 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;A0A2R8YHA2 P49815 TSC2 Tuberin 1 T(0.058)S(0.041)GPLS(0.899)PPT(0.002)GPPGPAPAGPAVR 142.84 5.9836e-11 0.0 7864.3 5919.3 5688.3 8555.2 7019.3 8427.0 11134.0 7433.1 8301.6 7063.1 True False 9195.57066299481 6506.928984709137 5823.930644997881 8075.87988033263 5643.91855346666 7985.073285114349 10079.306916820578 7237.989001020453 8422.995194915791 8343.584118531162 1.102112776998482 0.7798721619234592 0.6980130555719919 0.9679149590397298 0.6764381437626398 0.9570315552257024 1.208030838262224 0.8674915837361579 1.009517621594808 1.0 13.026451533952468 -6.989002400610532 24.929308837705722 1.020548161627643 0.837616131240933 0.26401967900844225 0.13959153210486314 276.45093201406206 626654.7979184713 0.04814008815460425 0.0424158645942259 1.0256462568632079e-07 6.989002400610532 -0.18293203038671002 TSGPLS(ph)PPTGPPGPAPAGPAVR ddPTM_PC-9_Lapatinib_30min_R1 1 TSGPLSPPTGPPGPAPAGPAVR 22 0 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;A0A2R8YHA2 P49815 TSC2 Tuberin 1 T(0.001)SGPLS(0.885)PPT(0.114)GPPGPAPAGPAVR 80.541 0.00049191 4463500.0 18821.0 15476.0 23006.0 18627.0 25230.0 22016.0 20207.0 20937.0 22377.0 19668.0 True False 18552.6090886513 15440.166272842605 21114.53548572815 19996.891717850434 23746.021004088507 21074.427001802647 21253.219586389645 21909.809454276296 19856.666619743602 23067.58759403733 0.8042717519991951 0.6693446468946621 0.9153334911876949 0.8668826610641925 1.0294106788274013 0.9135947534994995 0.9213455676606307 0.9498093099227981 0.8608037810107326 1.0 14.493579514558608 -5.32607288833486 6.886096223809469 0.9311182125736216 0.737375672758101 0.6455547409825944 0.057912779181873236 0.12875208948032504 11.619236076900677 0.014482889912107671 0.030613539242923937 4.719838208192692e-06 5.32607288833486 -0.1937425398155206 TSGPLSPPT(ph)GPPGPAPAGPAVR ddPTM_PC-9_Lapatinib_30min_R1 1 TSGPLSPPTGPPGPAPAGPAVR 22 0 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;A0A2R8YHA2 P49815 TSC2 Tuberin 1 TSGPLS(0.214)PPT(0.786)GPPGPAPAGPAVR 90.689 0.00049414 4367800.0 9254.2 7697.1 8124.0 7483.3 10651.0 10017.0 9729.6 6077.1 9301.5 8335.1 True False 9122.233410987572 7679.277837858413 7456.076079546878 8033.646845556995 10024.52912067168 9588.596260767497 10233.351080701572 6359.464251544276 8253.86712086272 9775.810929177373 0.9331433961924221 0.785538702977413 0.7627066576434187 0.8217882796382009 1.0254422055925785 0.980849192996245 1.04680329384835 0.6505306104646011 0.8443153392244747 1.0 13.255000667386655 -4.445996799653992 20.868750270058015 0.8753154226131585 3.2604018272331965 0.015273864015604488 0.12398577663788089 1289.5526294888639 382084.11050574115 0.03173777903762904 13203.211166382454 3.580990759497163e-05 4.445996799653992 2.385086404620038 TSGS(ph)SSSDVTK ddPTM_PC-9_Lapatinib_30min_R1 1 TSGSSSSDVTK 11 0 Q5M775;Q5M775-4;Q5M775-2;Q5M775-5;Q5M775-3 Q5M775 SPECC1 Cytospin-B 1 TSGS(0.595)S(0.387)S(0.009)S(0.009)DVTK 103.21 0.0029980000000000002 4573600.0 21089.0 31767.0 29179.0 26178.0 36246.0 20488.0 36123.0 38265.0 33202.0 22287.0 True False 20788.26699275104 31693.445463258646 26780.01525419724 28103.217447248004 34114.08154237779 19611.775999860674 37993.27218880353 40042.93159325036 29462.4411274401 26139.278254439203 0.7952884846474517 1.2124835718398683 1.0245124212505454 1.0751336427001488 1.3050888861701542 0.7502799353891888 1.453493544044246 1.531906550879993 1.1271329238953463 1.0 14.673931686210087 -7.286678285832594 24.98566055438516 1.3224587962444732 1.050253552106555 0.2371838512853527 0.21229767952110562 1020.5485305298207 1010303.8938209167 0.08504861882018983 0.05736542595062181 5.167990589445053e-08 7.286678285832594 -0.27220524413791813 TSGSS(ph)SSDVTK ddPTM_PC-9_Lapatinib_30min_R1 1 TSGSSSSDVTK 11 0 Q5M775;Q5M775-4;Q5M775-2;Q5M775-5;Q5M775-3 Q5M775 SPECC1 Cytospin-B 1 TS(0.001)GS(0.042)S(0.927)S(0.015)S(0.015)DVTK 93.766 0.006923100000000001 4008400.0 21717.0 27535.0 27180.0 25790.0 35879.0 23825.0 35524.0 34685.0 33226.0 31829.0 True False 21407.311597589967 27471.24439924536 24945.365317834105 27686.68263291795 33768.667760828015 22806.060288787612 37363.25889973306 36296.59172381782 29483.737994708903 37330.60024052342 0.5734521132706494 0.7358907765277385 0.6682283477123202 0.7416618659901234 0.9045841091023009 0.6109213391117937 1.0008748495603934 0.9723013155415822 0.7898008016143141 1.0 15.188071085540138 -3.557310874665778 0.18048814907189453 1.0289315914555075 7.986869227868676e-12 0.5267328639896358 0.10501722889005005 22.302664934812395 0.4799728580726789 0.2656124820896547 5.508118568440491 0.00027713356298351684 3.557310874665778 -1.0289315914475206 TSHSQGGDQALS(ph)KS(ph)T(ph)GS(ph)PT(ph)EK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSHSQGGDQALSKSTGSPTEK 21 1 Q7L1S5 Q7L1S5 CHST9 Carbohydrate sulfotransferase 9 5 T(0.018)S(0.018)HS(0.018)QGGDQALS(0.993)KS(0.988)T(0.988)GS(0.985)PT(0.992)EK 42.678999999999995 0.032835 7635200.0 2117.9 478.27 370.98 985.54 911.16 799.93 876.6 1036.3 0.0 0.0 True False 2476.4186395682655 525.749484823685 379.8255701494848 930.3233889637899 732.6247388167882 757.9802626037167 793.5621019655933 1009.0982230506111 0.0 0.0 0.0 TSIDAYDNFDNISLAQR ddPTM_PC-9_Lapatinib_30min_R1 2 TSIDAYDNFDNISLAQR 17 0 A0A087WVQ6;Q00610-2;Q00610;J3KS13;K7EJJ5 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 ; 185.32 1.4958e-07 7888000.0 26993.0 21613.8 21892.2 20536.4 22589.1 26280.0 20957.5 19013.5 24594.0 17021.3 False True 26608.07487009004 21563.754574047918 20092.307822335828 22046.715363422125 21260.45354987932 25156.06566167212 22042.576804164957 19896.93662219432 21823.96473369863 19963.409025543406 1.3328422433285172 1.0801639412615778 1.0064567527834296 1.104356241722699 1.0649710939988422 1.2601087133707802 1.1041489344811417 0.9966702879621394 1.0931982962316016 1.0 14.285070481201485 TSISDPPES(ph)PPLLPPREPVR ddPTM_PC-9_AZD4547_30min_R2 1 TSISDPPESPPLLPPREPVR 20 1 G5E9C8;Q07889 G5E9C8 SOS1 Son of sevenless homolog 1 1 T(0.013)S(0.013)IS(0.012)DPPES(0.961)PPLLPPREPVR 45.243 0.039577999999999995 7789600.0 32569.0 29900.0 41006.0 49710.0 47796.0 37137.0 32108.0 41608.0 33033.0 37166.0 True False 42925.2645227161 39564.59027363182 40462.233647155546 38250.12751184404 41160.35041901419 34814.81751927245 34965.54979856212 35178.43965672213 34779.056941793926 35864.82965244995 1.1968623562048297 1.1031584607269738 1.128186974237909 1.0665079935554955 1.1476521934686645 0.9707230692755912 0.9749258573760882 0.9808617522408631 0.969725976083596 1.0 15.130282157952955 -6.765504649748719 24.99993382345524 0.9777810747336506 1.123608750178136 0.8439511980476813 0.032046655414530716 39.278334752032926 241546.0075919343 0.010878208404100224 0.00994037541815099 1.7159133386958632e-07 6.765504649748719 0.14582767544448538 TSISDPPES(ph)PPLLPPREPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSISDPPESPPLLPPREPVR 20 1 G5E9C8;Q07889 G5E9C8 SOS1 Son of sevenless homolog 1 1 T(0.003)S(0.003)IS(0.007)DPPES(0.987)PPLLPPREPVR;TSISDPPES(0.999)PPLLPPREPVR;TSISDPPES(1)PPLLPPREPVR 65.881 0.021938 5950600.0 78481.0 90452.0 114017.0 110678.0 114991.0 84702.0 87784.0 82357.0 78133.0 71469.0 True False 91766.2832295942 99431.47678355705 116735.59769188019 104477.07048291744 92459.3390198004 80260.07801065093 79468.46401887706 80195.21601445458 79275.54731188618 84425.76395170731 1.0869464359491703 1.1777385495786952 1.3827011119337285 1.2375022219837981 1.0951554915474428 0.9506585934663356 0.9412821430237114 0.9498903209253438 0.9389970975830657 1.0 16.365395708497665 -6.539471908059469 2.7751378136826075 0.9514491229455901 1.2285264110195502 0.7580202464514494 0.07048203853658111 0.13793573856603525 2.1578925632427928 0.02655399802775727 0.0280536551916116 2.88754055106235e-07 6.539471908059469 0.27707728807396004 TSISDPPES(ph)PPLLPPREPVR ddPTM_PC-9_Lapatinib_30min_R1 2 TSISDPPESPPLLPPREPVR 20 1 G5E9C8;Q07889 G5E9C8 SOS1 Son of sevenless homolog 1 1 T(0.001)S(0.001)IS(0.003)DPPES(0.995)PPLLPPREPVR;T(0.003)S(0.003)IS(0.025)DPPES(0.97)PPLLPPREPVR 74.742 0.0011591 11608600.0 49435.0 68110.0 58573.0 53941.0 58480.0 49461.0 40424.0 43099.0 53020.0 36884.0 True False 48730.047834731275 67952.29547966599 53757.354038318495 57908.00108190108 55040.3213761037 47345.66832922242 42516.9569238489 45101.536880634965 47048.32927464833 43259.35025515929 1.1264627773488005 1.5708117454113106 1.2426759468470558 1.338623921541557 1.2723335198392018 1.0944609211641079 0.9828385464198726 1.0425847039913867 1.0875875156963817 1.0 15.40072437608607 -6.760839463538729 2.6112320565521134 1.031062801946381 1.3312037359631954 0.6181266984699442 0.10686487663360127 0.1740087563865119 2.4328379618297067 0.03817928720577146 0.03539273999387977 1.7344450148982173e-07 6.760839463538729 0.3001409340168144 TSKEPPS(ph)SPLQPQK ddPTM_PC-9_AZD4547_30min_R2 1 TSKEPPSSPLQPQK 14 1 Q92615;H0Y4V9;A0A087X183 Q92615 LARP4B La-related protein 4B 1 T(0.001)S(0.001)KEPPS(0.603)S(0.396)PLQPQK 60.541000000000004 0.026151 24997000.0 119390.0 90028.0 125860.0 169800.0 154930.0 159170.0 131240.0 136380.0 111030.0 152640.0 True False 157353.5365337303 119127.7904065058 124191.01416453684 130655.23338384861 133420.64378646473 149217.07473793236 142920.1057544317 115305.60470062862 116898.81912776257 147296.12006 1.0682802538833576 0.808763940000456 0.843138394371478 0.8870242700936533 0.9057987659968016 1.0130414479155994 0.9702910415848988 0.7828149489182725 0.793631353494883 1.0 17.168359903154638 -10.713878051020036 5.126179641082897 1.0000074851507479 0.8949772369899431 0.10308976944851422 0.09099284754843938 8.02855019856066e-06 1.2672318231487433e-06 0.09087179625060496 0.022038077599613216 1.932510885842253e-11 10.713878051020036 -0.10503024816080475 TSKEPPSS(ph)PLQPQK ddPTM_PC-9_AZD4547_30min_R2 2 TSKEPPSSPLQPQK 14 1 Q92615;H0Y4V9;A0A087X183 Q92615 LARP4B La-related protein 4B 1 T(0.022)S(0.002)KEPPS(0.107)S(0.869)PLQPQK;TSKEPPS(0.039)S(0.961)PLQPQK 86.411 0.0030727 68626000.0 350210.0 266522.0 365187.0 495120.0 421130.0 406062.0 367691.0 364610.0 323107.0 392746.0 True False 461569.49517947854 352670.02437822433 360344.3817710532 380977.7335277452 362663.36873293703 380670.8789485092 400414.7866881487 308267.9024042843 340185.77638398565 378996.08208257833 1.2178740546423605 0.9305373882503147 0.9507865616735817 1.0052286858330506 0.95690532403424 1.0044190347739954 1.056514316686006 0.8133801824819833 0.8975970794069148 1.0 18.531823408877372 -7.752304623807916 24.999075435228054 0.8916164633931104 1.0082566582405736 0.2557058659541058 0.08727881400957309 245.92228849559532 673020.2628684659 0.04053615646910112 0.02297555918706224 1.7688677998674212e-08 7.752304623807916 0.11664019484746324 TSKEPPSS(ph)PLQPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TSKEPPSSPLQPQK 14 1 Q92615;H0Y4V9;A0A087X183 Q92615 LARP4B La-related protein 4B 1 TSKEPPS(0.063)S(0.937)PLQPQK;TSKEPPS(0.018)S(0.982)PLQPQK;TSKEPPS(0.007)S(0.993)PLQPQK;TSKEPPS(0.007)S(0.993)PLQPQK 145.86 9.933999999999999e-08 73802000.0 643435.0 518821.0 598825.0 863123.0 991249.0 1024203.0 1087992.0 1089527.0 993302.0 809248.0 True False 752355.8370794702 570326.1201114627 613103.2590564603 814765.0165925229 797020.8741904858 970491.9916736638 984929.5213800472 1060928.07069928 1007827.1626072382 955958.2563963585 0.7870174581844179 0.5966014899661002 0.6413494051169699 0.8523018773475667 0.8337402484445156 1.015203315814325 1.0303059937919263 1.109805855643344 1.054258547236579 1.0 19.866588096194278 -6.426960669656302 1.1319549638330353 1.0638978915692117 0.6683197142313861 0.8529354795143596 0.0648331958805953 0.1635626575558371 0.44000218505439975 0.02903831956612321 0.036506074341591255 3.741444698084464e-07 6.426960669656302 -0.3955781773378255 TSKEPPSS(ph)PLQPQK ddPTM_PC-9_Lapatinib_30min_R1 4 TSKEPPSSPLQPQK 14 1 Q92615;H0Y4V9;A0A087X183 Q92615 LARP4B La-related protein 4B 1 TSKEPPS(0.129)S(0.871)PLQPQK;TSKEPPS(0.345)S(0.655)PLQPQK;T(0.008)S(0.002)KEPPS(0.062)S(0.929)PLQPQK;T(0.001)SKEPPS(0.117)S(0.882)PLQPQK 99.915 0.00098486 84860000.0 252864.0 289713.0 352754.0 313134.0 384082.0 405731.0 370791.0 367985.0 461289.0 339720.0 True False 249258.11299042127 289042.18734841346 323751.92778981786 336162.91894440283 361491.05189426534 388378.8309351558 389988.7436857029 385082.92649528856 409333.7752314833 398440.1493515548 0.6255848297318399 0.7254343916365303 0.8125484550608442 0.8436974022108323 0.9072656269268481 0.9747482314902919 0.9787887699580321 0.9664762126055705 1.0273406831556946 1.0 18.604003504252262 -4.670523053022618 0.42827244688377664 1.0151270007564697 0.3032865230024659 0.9815109648523186 0.017046736692032317 0.7087720711213435 0.09480020944486584 0.01322715822160431 0.2639073462266977 2.1353887333032345e-05 4.670523053022618 -0.7118404777540037 TSLAEDSCLGRHS(ph)PVPR ddPTM_PC-9_AZD4547_30min_R2 1 TSLAEDSCLGRHSPVPR 17 1 Q13469-3;Q13469-4;Q13469-2;Q13469;Q13469-5 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 T(0.002)S(0.001)LAEDS(0.002)CLGRHS(0.996)PVPR 65.528 0.01008 13160000.0 19484.0 21556.0 36800.0 40652.0 37647.0 33824.0 29101.0 38370.0 37856.0 29670.0 True False 25679.506707623834 28523.55544944506 36312.00795530715 31280.309467139097 32420.36388452232 31708.979933001352 31690.932623892986 32440.798154884324 39856.99087544429 28631.26233084515 0.8969044539806643 0.9962381371748301 1.2682643026950071 1.0925228900382804 1.1323414074410223 1.1074950020223349 1.1068646662411241 1.1330551122761734 1.3920794135753276 1.0 14.805303658629395 -5.050289802801141 5.292097266240742 1.152274739422738 0.9168351145957501 0.41511015567826326 0.10156155301498755 0.16365648135470978 10.525595940309298 0.02511180548839437 0.07543323264570845 8.906564086809925e-06 5.050289802801141 -0.23543962482698788 TSLAEDSCLGRHS(ph)PVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSLAEDSCLGRHSPVPR 17 1 Q13469-3;Q13469-4;Q13469-2;Q13469;Q13469-5 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 T(0.002)S(0.002)LAEDS(0.019)CLGRHS(0.977)PVPR 52.008 0.033375 13272000.0 18436.0 18406.0 22945.0 31055.0 28693.0 22122.0 34152.0 23281.0 24377.0 22253.0 True False 21556.850672402157 20233.22603898373 23492.095819397076 29315.089031668445 23070.812624423932 20961.883376444704 30916.875320931944 22669.898418258494 24733.467508246886 26287.292745348925 0.820048335948032 0.7696960746390913 0.8936673717971049 1.1151809855678363 0.8776412560972414 0.7974150696881307 1.1761148483577542 0.8623900010498241 0.9408906328942162 1.0 14.682077950034378 -5.518353592653725 24.960106730820726 0.9627426113744659 0.804074553781544 0.28685448731318564 0.10803421498148211 233.86941590062028 1289989.060825471 0.02905232067848377 0.052010250631255514 3.0314220645321716e-06 5.518353592653725 -0.1586680575929219 TSLAEDSCLGRHS(ph)PVPR ddPTM_PC-9_Lapatinib_30min_R1 2 TSLAEDSCLGRHSPVPR 17 1 Q13469-3;Q13469-4;Q13469-2;Q13469;Q13469-5 Q13469-3 NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 1 TSLAEDSCLGRHS(1)PVPR;TSLAEDS(0.009)CLGRHS(0.99)PVPR 84.62 0.001592 39442000.0 66574.0 81162.0 76912.0 83069.0 87600.0 76711.0 65158.0 87838.0 95397.0 70676.0 True False 65624.64255182378 80974.07437557846 70588.59224890583 89178.17137006045 82447.54022822637 73430.24935207498 68531.56241945755 91919.2741483841 84652.3852850551 82892.25243014972 0.7916860819667468 0.9768593807221292 0.851570444516371 1.0758324059924376 0.9946350570905514 0.8858517798626836 0.8267547377507518 1.1089006686824094 1.021233985122899 1.0 16.33894964528814 -3.9777611710243335 1.2254880051900505 0.9739119062468781 6.3677624565377e-17 0.26690577571052587 0.08786735141091885 13.690987073000233 4.111243257895403 0.027067393842152503 27.186483550079082 0.00010525405320403511 3.9777611710243335 -0.973911906246878 TSLAGDTS(ph)NSSSPASTGAK ddPTM_PC-9_Lapatinib_30min_R1 1 TSLAGDTSNSSSPASTGAK 19 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y6T5;H0Y4F5;H0Y314 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 TSLAGDT(0.07)S(0.316)NS(0.077)S(0.269)S(0.269)PASTGAK 122.16 3.4096999999999996e-05 5126300.0 33001.0 32512.0 34617.0 28462.0 28813.0 25269.0 18842.0 22571.0 25654.0 20211.0 True False 32530.39968835777 32436.720461531317 31770.923885484273 30555.19042644868 27118.275988537545 24188.303774916018 19817.546565385954 23619.731059486563 22764.576371403786 23704.444420535314 1.3723333528195445 1.368381383932845 1.340293968584259 1.289006815952983 1.144016518904143 1.020412178652942 0.8360266207385938 0.996426266756315 0.9603505556824056 1.0 14.53286995944643 -6.472271522105284 1.531667111445548 0.9449393276383921 1.3620326804576002 0.9406238108561649 0.045399804247955644 0.08535777134822121 0.40627812357122983 0.01838161056865778 0.02112023851444483 3.3707650161070574e-07 6.472271522105284 0.4170933528192081 TSLAGDTSNS(ph)SSPASTGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSLAGDTSNSSSPASTGAK 19 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y6T5;H0Y4F5;H0Y314 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 TSLAGDT(0.034)S(0.241)NS(0.392)S(0.319)S(0.014)PASTGAK 235.26 1.5639e-43 3932100.0 27404.0 28713.0 28209.0 28757.0 31698.0 28383.0 29718.0 23796.0 21948.0 19962.0 True False 32042.955946328322 31563.436882393744 28881.609543228227 27145.83852145191 25487.004445996918 26894.545514584133 26902.895900312004 23171.380213946108 22268.947978463417 23580.952580894933 1.3588490895948464 1.3385140729202833 1.224785531634029 1.1511765026594056 1.0808301470673518 1.140519893007793 1.1408740087161906 0.9826312204503284 0.944361679286252 1.0 14.52533437844282 -4.21453286517977 0.2897172636697997 0.9625924338967505 1.8846299888287334 0.8760214292182577 0.04732090450970503 4.052512341787034 0.21661959556770016 0.060619516528222214 1.403251820044774 6.101928786288218e-05 4.21453286517977 0.9220375549319829 TSLAGDTSNSS(ph)SPASTGAK ddPTM_PC-9_AZD4547_30min_R2 2 TSLAGDTSNSSSPASTGAK 19 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y6T5;H0Y4F5;H0Y314 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 TSLAGDTSNS(0.003)S(0.498)S(0.498)PASTGAK;TSLAGDTSNS(0.006)S(0.928)S(0.066)PASTGAK 380.03 0.0 13931600.0 67187.0 60068.0 65854.0 80926.0 72672.0 62951.0 50419.0 65052.0 57219.0 64886.0 True False 88551.06842358455 79483.80630623798 64980.732931760795 62269.76099423646 62582.747210030175 59014.66401851847 54906.19332545486 54999.708146247984 60243.47952509631 62614.36088976132 1.4142293743042005 1.2694181522698436 1.037792800379544 0.9944964718855541 0.9994951049682228 0.9425100437009896 0.8768945741077283 0.8783880784646245 0.9621351822333668 1.0 15.934205963358009 -4.856573895657928 0.8912530618477764 0.9275632639964905 1.6733044562347659 0.9378567455376287 0.04067440149667929 0.4525247772483898 0.30319846055567634 0.015146416446769291 0.3231004691799953 1.3913170406612871e-05 4.856573895657928 0.7457411922382754 TSLAGDTSNSSS(ph)PASTGAK ddPTM_PC-9_AZD4547_30min_R2 2 TSLAGDTSNSSSPASTGAK 19 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y6T5;H0Y4F5;H0Y314 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 TSLAGDTSNS(0.004)S(0.019)S(0.977)PASTGAK;TSLAGDT(0.002)S(0.008)NS(0.002)S(0.006)S(0.982)PAS(0.001)TGAK 273.82 1.0073999999999999e-91 12484300.0 47704.0 47345.0 53021.0 67049.0 58142.0 49292.0 49138.0 54813.0 42154.0 50544.0 True False 62872.87969515948 62648.34536806351 52317.90689669404 51591.888946723644 50069.98690397362 46209.76344777387 53511.186807080645 46342.91032743484 44382.17438090339 48774.46994439626 1.2890530592507852 1.2844495376266252 1.0726494200006143 1.0577642156960247 1.026561374445571 0.9474170298611917 1.0971146763477764 0.9501468776650276 0.9099468314366068 1.0 15.573838574008638 -5.314510376409944 1.1709159273654006 0.9884188716783536 1.3488786912852329 0.8272779074245306 0.0519479658837638 0.2940003990855825 0.6042955463987094 0.017329017305300006 0.1035388640234091 4.84718531316097e-06 5.314510376409944 0.36045981960687923 TSLAGDTSNSSS(ph)PASTGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSLAGDTSNSSSPASTGAK 19 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y6T5;H0Y4F5;H0Y314 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 TSLAGDTS(0.002)NS(0.002)S(0.006)S(0.99)PASTGAK;TSLAGDTSNSS(0.078)S(0.92)PAS(0.002)TGAK 313.59 1.5589999999999998e-156 9884500.0 56268.0 55945.0 49552.0 49712.0 57794.0 49620.0 58736.0 50365.0 42309.0 37669.0 True False 65793.06105634218 61498.84987237555 50733.50760700646 46926.797808478535 46469.68057770036 47017.839848982294 53172.10086818512 49042.972116128534 42927.68908423582 44498.09151236008 1.478559165578305 1.3820558990781262 1.1401277197003918 1.0545800103683962 1.0443072724769025 1.05662598666557 1.1949299185879847 1.1021365287656446 0.9647085442374971 1.0 15.441455840916177 -5.230278619991374 2.2635276268919085 1.0684046753070677 1.4769500860398412 0.8651249089084407 0.0582260386290398 0.11772824146073814 1.1119690786863579 0.016824266399071024 0.06413247935598489 5.884660060759752e-06 5.230278619991374 0.4085454107327735 TSLAGDTSNSSS(ph)PASTGAK ddPTM_PC-9_Lapatinib_30min_R1 3 TSLAGDTSNSSSPASTGAK 19 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y6T5;H0Y4F5;H0Y314 H3BPE1 MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 1 TSLAGDTSNSS(0.003)S(0.997)PASTGAK;TSLAGDT(0.002)S(0.002)NS(0.012)S(0.042)S(0.941)PAS(0.001)TGAK;TSLAGDTSNSS(0.004)S(0.462)PAS(0.462)T(0.071)GAK 292.65 4.6116e-121 15698500.0 87976.0 85445.0 93900.0 79706.0 76399.0 71398.0 62184.0 64678.0 71732.0 53200.0 True False 86721.44610717754 85247.15735222535 86179.90446448194 85567.84513142133 71905.3610262132 68344.47397686703 65403.58325135117 67683.17599864751 63652.7867885529 62395.54911545588 1.3898659012794223 1.3662377935721852 1.3811867302428225 1.3713773874012671 1.1524117031674888 1.0953421349077854 1.0482091139278102 1.0847436549265312 1.020149476860451 1.0 15.929155500013907 -6.412281899978465 1.9838355405342498 1.0507789772438145 1.3841490339926812 0.9712313703684062 0.026654263157778697 0.04981510398179939 0.38807636956608893 0.009358869430722882 0.010946740119795672 3.8700635805614075e-07 6.412281899978465 0.33337005674886666 TSLDIEEYS(ph)DTEVQK ddPTM_PC-9_AZD4547_30min_R2 4 TSLDIEEYSDTEVQK 15 0 P51580 P51580 TPMT Thiopurine S-methyltransferase 1 TSLDIEEYS(0.995)DT(0.005)EVQK;TSLDIEEYS(0.999)DT(0.001)EVQK;TSLDIEEY(0.078)S(0.817)DT(0.105)EVQK;TSLDIEEYS(0.991)DT(0.009)EVQK 187.08 3.3632e-07 13850000.0 85693.0 93773.0 106009.0 145713.0 130685.0 118017.0 106554.0 122324.0 108099.0 122993.0 True False 112941.59147487197 124083.28841903934 104603.25139494977 112121.11909340853 112541.64353730186 110637.37833352135 116037.09957755015 103421.63652588152 113812.89245151759 118687.05250615554 0.9515915096890152 1.0454660874875457 0.8813366680373553 0.9446786041602434 0.9482217407957372 0.9321773183960677 0.9776727716069287 0.8713809496660784 0.9589326725054095 1.0 16.85680303533087 -5.256911665077071 24.99914369803562 0.9363333416970234 0.9985287931759717 0.23392280531775655 0.04260403834217005 478.0157030376994 2639272.8681147667 0.010164192999572528 0.025047274087674203 5.534626713428234e-06 5.256911665077071 0.06219545147894823 TSLDIEEYS(ph)DTEVQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TSLDIEEYSDTEVQK 15 0 P51580 P51580 TPMT Thiopurine S-methyltransferase 1 T(0.002)S(0.001)LDIEEYS(0.939)DT(0.058)EVQK;TSLDIEEYS(1)DTEVQK;TSLDIEEYS(0.997)DT(0.003)EVQK;TSLDIEEYS(0.985)DT(0.015)EVQK 169.15 8.4361e-05 6263900.0 61061.7 62496.0 57484.4 78235.5 77480.5 63008.799999999996 70806.4 67715.9 57059.7 48230.2 True False 71398.23978645145 68700.18985832468 58855.046106801026 73852.2185779134 62298.75222342304 59704.50760734697 64099.10519805686 65938.42937592686 57894.09016615313 56973.953469946886 1.2531733439230825 1.205817495086825 1.0330167124148475 1.2962452854332744 1.093460229265728 1.047926358820095 1.1250598088101507 1.1573434062410402 1.0161501289653632 1.0 15.798014899038542 -1.5228787470730716 0.10966065625224015 0.9461186590426722 1.788346104600344 0.4115688321179035 0.07521917216991003 119.8650168594349 0.9216510981747069 0.7092410125707229 15.268162527240579 0.029999999876162323 1.5228787470730716 0.8422274455576717 TSLDIEEYS(ph)DTEVQK ddPTM_PC-9_Lapatinib_30min_R1 4 TSLDIEEYSDTEVQK 15 0 P51580 P51580 TPMT Thiopurine S-methyltransferase 1 TSLDIEEY(0.015)S(0.972)DT(0.013)EVQK;TSLDIEEYS(1)DTEVQK;TSLDIEEYS(0.993)DT(0.007)EVQK;TSLDIEEYS(0.969)DT(0.031)EVQK 197.47 8.8003e-10 11437200.0 62903.1 86633.8 102938.6 83034.3 92281.6 89904.0 78407.2 86733.9 101682.3 76389.4 True False 62006.09025898425 86433.20475886471 94475.38566248716 89140.91941630487 86853.77772060611 86059.01549646014 82466.74116662395 90763.87363166918 90229.76861191208 89593.2060075225 0.6920847352396123 0.9647294545035874 1.054492744176994 0.9949517757944765 0.9694237051112293 0.9605529183678769 0.9204575306714642 1.0130664776528746 1.0071050320973682 1.0 16.45110171416622 -4.764674179486372 4.994458375156117 0.9877962389014476 0.6738867217235163 0.8747832604697081 0.03360468046285379 0.05896592122593169 3.8692391073017163 0.00904451720107029 0.06492710135958275 1.719197696213559e-05 4.764674179486372 -0.31390951717793136 TSLEASMEAS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 TSLEASMEASPK 12 0 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1;Q8IWC1-3 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 1 TSLEAS(0.183)MEAS(0.817)PK;TSLEAS(0.001)MEAS(0.999)PK;TSLEAS(0.001)MEAS(0.999)PK 93.766 0.0045257 38590200.0 168779.0 133493.0 129237.0 155118.0 184512.0 172992.0 175860.0 142425.0 155731.0 200437.0 True False 222447.21117871307 176642.00165210466 127523.23293804431 119357.94164921007 158895.693708954 162174.78289290966 191511.1993140381 120416.48885090981 163962.6227288625 193419.76163827494 1.1500748904588352 0.9132572605608558 0.6593081899073612 0.6170927967144743 0.8215070288738835 0.8384602561769348 0.9901325370889136 0.62256559428559 0.8477035714452907 1.0 17.561375676495928 -4.866602011704291 3.406104194834044 0.7882549820643674 1.1655481132318395 0.40027975888254796 0.1294248727841364 0.2589392629545428 5.039955818055733 0.03313149959545131 0.22360620002751885 1.3595587781583054e-05 4.866602011704291 0.3772931311674721 TSLEASMEAS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSLEASMEASPK 12 0 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1;Q8IWC1-3 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 1 TSLEAS(0.007)MEAS(0.993)PK;TSLEAS(0.004)MEAS(0.996)PK 108.32 0.0023098000000000003 4372500.0 65299.0 63640.0 49634.0 78890.0 72501.0 63840.0 70291.0 93242.0 58122.0 58007.0 True False 76352.83098596155 69957.75861789213 50817.462797993234 74470.04906483075 58294.94950278326 60492.11801610299 63632.52761722974 90794.4962980651 58971.92429397891 68523.20991684077 1.1142623218997292 1.0209352233030577 0.7416094905604234 1.0867857643447674 0.8507329060259954 0.8827974943017957 0.9286273613634515 1.3250181421485157 0.8606124022144727 1.0 16.064305114489166 TSLEASMEAS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 TSLEASMEASPK 12 0 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1;Q8IWC1-3 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 1 TSLEAS(0.001)MEAS(0.999)PK 92.781 0.004996899999999999 17372000.0 92558.0 76294.0 49624.0 80514.0 72596.0 56057.0 58358.0 50829.0 49409.0 55529.0 True False 91238.1059469417 76117.3459304894 45544.10627417949 86435.26814683055 68326.04600922739 53659.57278524942 61379.49169211297 53190.700900387375 43844.03812016408 65127.113662258445 1.4009235296391573 1.168750488855149 0.6993109891275985 1.3271779338337284 1.0491182883300836 0.8239206340929164 0.9424568085485839 0.8167212994610524 0.6732071429962965 1.0 15.990970669521403 -6.663722230261758 4.448358802248704 0.8454961396490022 1.1255991850422813 0.35083627425788133 0.19114446552918476 0.2700383564659222 9.432670775574303 0.06612062656833356 0.06541255471468722 2.1690909868162934e-07 6.663722230261758 0.2801030453932791 TSLPLS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 2 TSLPLSPVK 9 0 Q86XL3;Q86XL3-2 Q86XL3 ANKLE2 Ankyrin repeat and LEM domain-containing protein 2 1 T(0.005)S(0.02)LPLS(0.976)PVK;T(0.003)S(0.011)LPLS(0.986)PVK 110.08 0.002326 26805000.0 270010.0 266520.0 283360.0 303150.0 297590.0 253380.0 303070.0 336460.0 312290.0 298680.0 True False 355867.5634431074 352667.377917336 279602.4612558649 233263.45112081128 256274.7652773126 237536.10854493568 330042.6428756139 284467.8380816369 328797.0118473291 288223.30411111703 1.2346939278231017 1.2235907814774556 0.9700897091515938 0.8093150269031771 0.8891535195867177 0.8241391489057379 1.1450935374343445 0.9869702901329854 1.1407717806210769 1.0 18.136827462851322 -5.261528622847806 6.4459898927875745 0.9621467379020494 1.231048910025683 0.48016027272421835 0.10732299100626287 0.11665314888510446 27.064840006283212 0.029901661334425768 0.07116160835466158 5.4761000869014e-06 5.261528622847806 0.26890217212363354 TSLPLS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 2 TSLPLSPVK 9 0 Q86XL3;Q86XL3-2 Q86XL3 ANKLE2 Ankyrin repeat and LEM domain-containing protein 2 1 T(0.003)S(0.002)LPLS(0.995)PVK;TS(0.001)LPLS(0.999)PVK 115.29 0.0019879999999999997 16774500.0 198960.0 233100.0 144465.0 126575.0 188950.0 200864.0 198654.0 182789.0 229080.0 179801.0 True False 196122.7939152042 232560.27127162094 132587.64535102647 135883.7477418219 177836.33248999313 192273.51495685353 208939.33209851268 191282.04424405142 203278.59808065702 210879.36328022668 0.9300236441561461 1.1028118999135237 0.6287369389238795 0.6443672136910477 0.8433083717806736 0.911770179718113 0.9908002795933332 0.907068578303068 0.9639568088534609 1.0 17.68605839389273 -6.854708623173502 3.3948830334760003 0.9567859802915306 0.8228796135058982 0.19782086560002365 0.12858291583391185 0.4714612358410598 10.713719986712618 0.053052228673170845 0.04694745647542688 1.3973055267753886e-07 6.854708623173502 -0.1339063667856324 TSLPTVGPSGLYS(ph)PSTNR ddPTM_PC-9_AZD4547_30min_R2 3 TSLPTVGPSGLYSPSTNR 18 0 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 TSLPTVGPS(0.032)GLY(0.002)S(0.826)PS(0.055)T(0.086)NR;TSLPTVGPS(0.001)GLYS(0.821)PS(0.061)T(0.118)NR;TSLPTVGPS(0.046)GLYS(0.916)PS(0.019)T(0.019)NR 127.3 4.3213e-05 22384600.0 50744.0 60018.0 67143.0 93206.0 75696.0 83929.0 68529.0 86409.0 70342.0 69070.0 True False 66879.53645923139 79417.64478404113 66252.6399495431 71718.79671834518 65186.91700806972 78680.90636225385 74627.94824173604 73056.47453128475 74060.13451396074 66651.88032327179 1.0034155996028233 1.191528947103269 0.994010065855722 1.0760206069280878 0.9780206753643442 1.1804754191575608 1.1196675604615969 1.096090225466254 1.1111484650509151 1.0 16.024357955460765 -6.764790635096623 24.99998314636436 1.1086189070811288 1.0550304124497851 0.11833635113429775 0.06974051300953585 190.79991124285218 1423331.2865169954 0.02316467628199007 0.02126867777674678 1.7187367569557153e-07 6.764790635096623 -0.05358849463134363 TSLPTVGPSGLYS(ph)PSTNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSLPTVGPSGLYSPSTNR 18 0 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 TSLPTVGPS(0.114)GLYS(0.81)PS(0.024)T(0.052)NR 150.92 6.517300000000001e-05 6232300.0 17999.0 19151.0 23121.0 27753.0 35996.0 24609.0 29247.0 20148.0 22324.0 19203.0 True False 21045.8752035456 21052.18471545025 23672.29232688079 26198.089386440002 28942.84219944809 23318.460718331437 26476.512430056704 19619.136348570595 22650.446267141277 22684.351889135643 0.9277706194297413 0.9280487632328126 1.0435516272439023 1.1548969754338547 1.2758946052723623 1.0279535792909071 1.1671707686185764 0.8648753309970875 0.9985053299225796 1.0 14.469409820825629 -7.76309575069796 24.99996542059032 0.9487677625514815 1.0771617803830642 0.2107281815767199 0.10671418411384843 73.70066492625672 1112308.2371266878 0.05993898507678444 0.031176189359170915 1.7254574313252584e-08 7.76309575069796 0.12839401783158266 TSLPTVGPSGLYS(ph)PSTNR ddPTM_PC-9_Lapatinib_30min_R1 1 TSLPTVGPSGLYSPSTNR 18 0 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 TSLPTVGPSGLYS(0.958)PS(0.013)T(0.029)NR 185.71 1.3027e-10 7856100.0 14911.0 14470.0 16124.0 12534.0 14724.0 14099.0 15612.0 16366.0 15316.0 11612.0 True False 14698.36640565749 14436.495604034148 14798.346960439916 13455.79217219828 13857.963268497784 13496.018636374247 16420.312969897324 17126.424107020404 13590.950795369938 13619.11872798258 1.079245045089256 1.0600168698413752 1.0865862363057626 0.9880075532751821 1.0175374446236716 0.9909612292787047 1.2056810207667297 1.257528071315769 0.9979317360267396 1.0 13.733345731364654 -7.253378670595925 24.975071936053673 1.1367458804792905 1.0372368748530434 0.16090106244514912 0.08184204520644897 850.7661470878497 2635995.0200350364 0.031366854619404055 0.023874093907740358 5.5798346492162696e-08 7.253378670595925 -0.0995090056262471 TSLPTVGPSGLYSPST(ph)NR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSLPTVGPSGLYSPSTNR 18 0 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 TSLPTVGPS(0.001)GLYS(0.129)PS(0.215)T(0.655)NR 160.09 1.6133e-05 5602600.0 42290.0 35326.0 29223.0 37177.0 45126.0 40368.0 45484.0 33688.0 28734.0 30273.0 True False 49448.861734426515 38832.931818599296 29919.787148844665 35094.09321946023 36283.88423970146 38251.03101619743 41175.42624435664 32803.72569538645 29154.18039061271 35761.25525906386 1.3827496092127098 1.085893980434507 0.8366537173289339 0.9813439982805264 1.014614391381162 1.069622157810093 1.151397677348603 0.917297937607271 0.8152448838669735 1.0 15.126109757128924 -4.816060419260051 3.5023238132867505 0.9807757327808861 1.416127950305336 0.6229410900013219 0.09579356995722293 0.1867249698431013 3.8192246197545527 0.02601410614036184 0.20461168548686226 1.527353557285288e-05 4.816060419260051 0.43535221752444975 TSLSVDQAPT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 TSLSVDQAPTPK 12 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 TSLSVDQAPT(1)PK 94.09 0.011731 0.0 13519.0 18352.0 14062.0 17451.0 16544.0 17576.0 18790.0 22509.0 15028.0 15341.0 True False 17817.760787331466 24283.92510707995 13875.528692052423 13427.941565262332 14247.151170227024 16476.96994153358 20462.27359894675 19030.751255363346 15822.349399729936 14803.916259436977 1.2035842729097626 1.640371688241603 0.9372877047455102 0.9070533316954215 0.9623906890951889 1.1130142627651038 1.3822203017328452 1.28552140675829 1.0687948460694476 1.0 13.853691259503362 -5.268100499878533 24.973032481375967 1.0935374161928786 1.4219779852519447 0.3786149505975408 0.1737002873601602 536.8338655500162 2012636.5992161739 0.04936760553428069 0.10672600580059992 5.393857890641543e-06 5.268100499878533 0.32844056905906616 TSLVLNSDTCFENLTDPSSPT(ph)ISSYENLLR ddPTM_PC-9_AZD4547_30min_R2 1 TSLVLNSDTCFENLTDPSSPTISSYENLLR 30 0 Q8IX90;Q8IX90-3 Q8IX90 SKA3 Spindle and kinetochore-associated protein 3 1 TSLVLNSDT(0.002)CFENLT(0.051)DPS(0.074)S(0.245)PT(0.522)IS(0.064)S(0.023)Y(0.018)ENLLR 58.711999999999996 0.0028206999999999998 5107600.0 2575.7 2614.5 4083.9 7640.2 4807.5 6000.3 1568.2 5868.7 7104.3 5007.0 True False 3394.7190221118203 3459.5859956658983 4029.744817627143 5878.869929913315 4140.061608490476 5625.10029245471 1707.7667619940537 4961.827264309866 7479.8187942841 4831.706454012188 0.7025921492587548 0.716017421297004 0.8340210350073924 1.2167274617918014 0.8568528837368878 1.1642057202758453 0.35345002397154024 1.0269306116868147 1.5480697897267646 1.0 12.23831709234552 -5.530493200796225 23.703877133312844 0.998111479075213 0.7257333088136746 0.1654923999156669 0.2854541629443957 181.53869880362888 565129.0758873059 0.07922741751686445 0.13764804286604676 2.9478596271846345e-06 5.530493200796225 -0.27237817026153843 TSMPS(ph)GDESIDEK ddPTM_PC-9_AZD4547_30min_R2 1 TSMPSGDESIDEK 13 0 Q03468 Q03468 ERCC6 DNA excision repair protein ERCC-6 1 T(0.03)S(0.046)MPS(0.922)GDES(0.002)IDEK 91.307 0.0045607 4025600.0 26453.0 26691.0 30960.0 34749.0 26960.0 31297.0 26540.0 29132.0 29128.0 26656.0 True False 34864.50374341887 35318.34377904703 30549.450171095345 26738.154916698244 23217.06936347441 29339.99364247707 28902.008585207393 24630.318786762855 30667.646614009438 25722.781553454955 1.3553939985443 1.3730375039593354 1.1876417839031135 1.0394737000403018 0.902587821430844 1.1406228980915274 1.1235957715204956 0.9575293688817504 1.19223679407604 1.0 14.650759037627314 -5.470621336015587 2.7545503576441925 1.0501616262360358 1.3663504294056175 0.6968379846778792 0.082351144804956 0.14787400519455984 2.195107714176915 0.02300824905516467 0.05403184778692776 3.3835972551973527e-06 5.470621336015587 0.31618880316958164 TSNRYS(ph)PESQAQSVHHQRPGSR ddPTM_PC-9_AZD4547_30min_R2 1 TSNRYSPESQAQSVHHQRPGSR 22 2 O75376-2;O75376;A0A088AWL3;E7EVK1;J3KS29;J3QKP0 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 T(0.029)S(0.029)NRY(0.426)S(0.514)PES(0.002)QAQSVHHQRPGSR 67.418 0.0010097 2105700.0 1089.0 1369.4 7266.3 14555.0 10656.0 8945.2 4946.0 10855.0 4647.7 6657.3 True False 1435.2793473928527 1812.0317699234586 7169.944114283925 11199.569622508356 9176.598335948933 8385.855229916155 5386.1844183283965 9177.609173084946 4893.367933532395 6424.229953324418 0.2234165585324546 0.28206209663864323 1.1160783730310921 1.743332617898086 1.4284355327598783 1.305347923540102 0.8384171266380569 1.4285928803553656 0.7617049777304702 1.0 12.64930781926439 -5.279813519281331 4.49589018059187 1.242396265270637 0.2343517069356799 0.6493999431024482 0.2793810717241395 0.1099314659920294 5.82592560611311 0.07519276054002963 0.18231778719361894 5.250328545174131e-06 5.279813519281331 -1.008044558334957 TSNS(ph)LTEDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSNSLTEDSK 10 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0;H7C3N7 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 TS(0.002)NS(0.995)LT(0.002)EDS(0.001)K;T(0.007)S(0.002)NS(0.907)LT(0.082)EDS(0.003)K 101.32 0.0036473 23464000.0 92251.0 93991.0 69253.0 87923.0 96539.0 83117.0 82795.0 92566.0 70954.0 67296.0 True False 107867.2722596968 103321.80531512086 70904.25416346498 82996.95936021206 77622.87596101017 78758.198200884 74952.05821610922 90136.24058178431 71991.56801822013 79496.23208515721 1.3568853445047335 1.2997069496884008 0.8919196835330709 1.0440363924582592 0.9764346551401293 0.9907161149036268 0.9428378710555712 1.1338429283696039 0.9055972356161736 1.0 16.27859886157058 -5.194769361065467 6.2377776631144695 0.9910957429186609 1.3359882572033177 0.8093006139699335 0.06653963063209757 0.08713660476819989 6.413810237836531 0.01591171844996131 0.04311552377041752 6.386025361028465e-06 5.194769361065467 0.34489251428465684 TSNS(ph)LTEDSK ddPTM_PC-9_Lapatinib_30min_R1 2 TSNSLTEDSK 10 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0;H7C3N7 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 T(0.002)SNS(0.988)LT(0.009)EDS(0.001)K;TSNS(0.987)LT(0.011)EDS(0.001)K 105.03 0.0025194 40650000.0 150236.0 154203.0 159394.0 113418.0 124039.0 137686.0 143891.0 136916.0 120582.0 106668.0 True False 148093.60709009218 153845.9524277042 146289.24059863322 121759.13807135695 116743.26989005676 131797.49074174248 151340.97191592964 143277.61719643223 107000.78537524787 125105.421673824 1.1837505130369423 1.2297304974424912 1.1693277448841495 0.973252289487569 0.9331591575178163 1.0534914392868289 1.2097075401776527 1.1452550599284732 0.8552849584266723 1.0 16.932784787141586 -5.634442353950873 5.669501063032524 1.035952471861746 1.2047549474906507 0.39614874170568337 0.09598751846535711 0.23467379540746144 10.7190344383078 0.028220683650584135 0.04953812753399268 2.3203721595737667e-06 5.634442353950873 0.1688024756289046 TSNSLT(ph)EDSK ddPTM_PC-9_AZD4547_30min_R2 2 TSNSLTEDSK 10 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0;H7C3N7 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 TSNS(0.154)LT(0.845)EDS(0.001)K;TSNS(0.128)LT(0.856)EDS(0.016)K 136.01 0.00028003 19996400.0 78032.0 68349.0 82072.0 107318.0 84689.0 84256.0 83628.0 101626.0 72351.0 78254.0 True False 102844.55283357103 90441.47761245693 80983.67165510793 82577.49314657174 72931.3941885492 78987.45900056051 91070.72999109743 85922.03683315824 76175.32615250612 75514.35127866393 1.3619206295509694 1.197672708313533 1.0724275622293442 1.0935337687248787 0.9657951495791431 1.0459926843452587 1.2060055929637423 1.1378239417840954 1.0087529702983615 1.0 16.204463229960915 -4.858391561840392 1.8914378213855998 1.071496893918928 1.426081019463408 0.6607320194365038 0.06642612367265698 0.4483424083302626 1.9450938335379047 0.019441801099206565 0.26938108875549094 1.3855060871072924e-05 4.858391561840392 0.35458412554447993 TSNSLT(ph)EDSK ddPTM_PC-9_Lapatinib_30min_R1 1 TSNSLTEDSK 10 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0;H7C3N7 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 T(0.105)S(0.001)NS(0.385)LT(0.497)EDS(0.011)K 125.53 0.00092054 8245300.0 51414.0 43025.0 42492.0 42609.0 41547.0 41573.0 43257.0 35896.0 48443.0 34173.0 True False 50680.82693182716 42925.37825594811 38998.471783863366 45742.60799945721 39103.2871445448 39795.01970139631 45496.635801873475 37563.85920479067 42986.83921259502 40079.75751733973 1.2644993400945874 1.070998950963645 0.9730216498189002 1.1412895394805609 0.9756368193502051 0.9928957200946081 1.135152471473667 0.9372277062439661 1.0725324172432331 1.0 15.290586159799394 -4.778604147442106 3.705187329442431 1.0303415531332083 1.2902597415124175 0.5390912541767825 0.06514539382418007 0.19312460470023352 4.6048450886175685 0.015444070764117674 0.1393806887442157 1.664929515911584e-05 4.778604147442106 0.2599181883792092 TSNTLEKDLDLLASVPS(ph)PSSSGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSNTLEKDLDLLASVPSPSSSGSR 24 1 A0A087WV97;Q8WU79-3;Q8WU79-2;Q8WU79 A0A087WV97 SMAP2 Stromal membrane-associated protein 2 1 TSNTLEKDLDLLAS(0.001)VPS(0.58)PS(0.146)S(0.19)S(0.064)GS(0.017)R 66.365 0.000566 1574200.0 12236.0 3525.6 6154.6 18425.0 17494.0 30498.0 15198.0 32282.0 24962.0 13223.0 True False 14307.313127983998 3875.598268121317 6301.349005450483 17392.706984655953 14066.176281729768 28898.631191339406 13758.335416008544 31434.631705606313 25327.02202653562 15620.225226789602 0.9159479405870613 0.24811410923028424 0.4034096124710993 1.1134735083605862 0.9005104649583061 1.8500777531540684 0.8808026271229554 2.0124313989848286 1.6214248936115396 1.0 13.931127635284772 -6.226610616259798 1.3786595463232525 1.497198227575221 0.5023599239710115 0.4878387343441163 0.39260609605964064 0.32835644413522563 1.2580901207986512 0.14480409852408524 0.20962794615604344 5.934571734091706e-07 6.226610616259798 -0.9948383036042094 TSPADHGGSVGS(ph)ESGGSAVDSVAGEHSVSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSPADHGGSVGSESGGSAVDSVAGEHSVSGR 31 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;A0A0A0MSW0;X6RE05 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 T(0.037)S(0.037)PADHGGS(0.42)VGS(0.5)ES(0.006)GGSAVDSVAGEHSVSGR 81.765 2.2510999999999998e-07 7339000.0 16684.0 11303.0 16334.0 16196.0 20337.0 17916.0 11508.0 16212.0 8269.8 17086.0 True False 19508.271675979475 12425.087141075355 16723.464507039967 15288.590628140453 16352.110840376023 16976.45342068454 10417.878929295059 15786.452178033884 8390.730180075476 20183.556547298416 0.9665428206502422 0.6156044457258184 0.8285687642735301 0.75747753337292 0.8101699421534687 0.8411031713316576 0.5161567489298361 0.7821442242371754 0.41572109258408085 1.0 14.30089279388744 -7.229337084378757 24.935282967085254 0.6603507765240587 0.794100946174683 0.11351235036192153 0.1665607372859232 1256.691760737521 976129.6208604454 0.05851889392244246 0.0453244411288983 5.8974316420791765e-08 7.229337084378757 0.13375016965062425 TSPDTLRR ddPTM_PC-9_AZD4547_30min_R2 3 TSPDTLRR 8 1 J3QL05;J3KP15;Q01130-2;Q01130 J3QL05 SRSF2 Serine/arginine-rich splicing factor 2 0 ;; 105.57 0.0034471 8395600.0 23227.699999999997 15380.9 25294.199999999997 34917.0 26421.2 21573.7 18356.6 24663.0 17800.600000000002 24600.199999999997 False True 30613.625433826426 20352.47513510713 24958.7823810633 26867.425112272358 22753.072443109424 20224.693128565264 19990.30183855379 20851.900049359192 18741.503375354867 23738.95448571811 1.289594512354968 0.8573450506150825 1.0513850724166924 1.1317863694644348 0.958469862554317 0.8519622522016669 0.8420885532503298 0.8783832523839314 0.7894830998825234 1.0 14.534968776556024 -6.529600327557573 3.8487776651246484 0.8640923742776381 1.0638321353850833 0.4371394588574874 0.11120077052502661 0.21634417674854511 7.1744906313341446 0.035832149722484705 0.037777582384327664 2.953926415021926e-07 6.529600327557573 0.19973976110744518 TSPDTLRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSPDTLRR 8 1 J3QL05;J3KP15;Q01130-2;Q01130 J3QL05 SRSF2 Serine/arginine-rich splicing factor 2 0 ;; 101.64 0.0028619 4555300.0 22797.2 14686.500000000002 15981.999999999998 26017.600000000002 25525.6 24224.6 21718.300000000003 27422.3 21757.300000000003 20312.4 False True 26656.315694775803 16144.478660302862 16363.071492072526 24559.91822219729 20524.041917052786 22954.21933102894 19660.985397124517 26702.49368132856 22075.45935173235 23994.877327130074 1.1109169399518681 0.6728302228929892 0.6819402020268484 1.023548396908383 0.8553509833470601 0.9566299930642069 0.8193826177596085 1.112841433497853 0.9200071769807502 1.0 14.550438816900556 -7.117307255711162 0.7496721973207525 1.0031167819944276 0.8394579530130313 0.1063647978271487 0.14146816020953573 1.3661466404139575 1.5622273412507908 0.11297532908689573 0.07951112854118635 7.632955743056594e-08 7.117307255711162 -0.16365882898139628 TSPDTLRR ddPTM_PC-9_Lapatinib_30min_R1 2 TSPDTLRR 8 1 J3QL05;J3KP15;Q01130-2;Q01130 J3QL05 SRSF2 Serine/arginine-rich splicing factor 2 0 ; 110.12 0.0023837 8716900.0 18656.0 11958.3 11634.3 12545.900000000001 13199.0 13212.2 10013.5 7248.200000000001 12685.6 8102.0 False True 18389.962018908613 11930.611291065765 10677.772763696728 13468.567337895529 12422.66077023243 12647.145005142487 10531.95003356821 7584.977832855023 11256.814142709904 9502.419904763596 1.9352925047744587 1.2555340019319614 1.1236898464509997 1.4173828848737458 1.307315493814887 1.3309393956377817 1.1083439943848943 0.7982153923815393 1.1846260484728552 1.0 13.214079244424429 -2.746019695843626 1.352193484042902 1.1601603159440268 199.96629653600692 0.6507973461792008 0.16862477825544528 252.40867566940042 2.4047949767860244 0.05320694925521942 153762.07444940836 0.0017946522350746495 2.746019695843626 198.80613622006288 TSPKPAVVETVTTAKPQQIQALMDEVTK ddPTM_PC-9_AZD4547_30min_R2 1 TSPKPAVVETVTTAKPQQIQALMDEVTK 28 2 H0YI94;H0YIP0;P56192 H0YI94 MARS Methionine--tRNA ligase, cytoplasmic 0 80.453 1.2811e-05 2876400.0 16470.0 16760.0 16459.0 20645.0 19743.0 19380.0 18718.0 15878.0 16840.0 22108.0 False True 21707.117402718344 22177.34224033675 16240.742905880446 15885.614212070424 17002.025238986476 18168.165536351902 20383.86573842923 13424.419940142136 17730.128020458626 21334.005649151484 1.0174890622840769 1.0395301569266626 0.7612608327272281 0.7446146998044992 0.7969448175177875 0.8516059213228203 0.9554635952409601 0.6292498540083618 0.8310735598386703 1.0 14.380867249475926 -5.255221438452201 24.591602259971108 0.8103042390819067 1.0285096455654905 0.4060146477948181 0.09955669886148545 354.9322394164217 1403723.473992008 0.02494520274265701 0.062495917744626095 5.5562088456833685e-06 5.255221438452201 0.21820540648358377 TSPKPAVVETVTTAKPQQIQALMDEVTK ddPTM_PC-9_Lapatinib_30min_R1 2 TSPKPAVVETVTTAKPQQIQALMDEVTK 28 2 H0YI94;H0YIP0;P56192 H0YI94 MARS Methionine--tRNA ligase, cytoplasmic 0 ; 63.823 0.00045915 9826800.0 26695.8 19867.8 22822.8 18093.0 24541.9 20455.4 16083.6 19699.7 20120.3 16865.0 False True 26315.11299658984 19821.797329773988 20946.397482555694 19423.61957647867 23098.393693231854 19580.57022586637 16916.3301103408 20615.01997929057 17854.139937848122 19780.09277880007 1.3303836989477562 1.002108410280998 1.0589635608284733 0.9819781835046062 1.1677596233516294 0.9899129617254604 0.8552199577380852 1.0422104794870002 0.9026317589866845 1.0 14.271761572643483 TSPLKDNPS(ph)PEPQLDDIKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSPLKDNPSPEPQLDDIKR 19 2 Q96JC9-2;Q96JC9 Q96JC9-2 EAF1 ELL-associated factor 1 1 T(0.003)S(0.003)PLKDNPS(0.995)PEPQLDDIKR 47.855 0.024435 19229000.0 21193.0 21782.0 14746.0 28274.0 25253.0 26992.0 27205.0 21605.0 24645.0 26258.0 True False 24780.556319170042 23944.37300777699 15097.600564516413 26689.899445544786 20304.855930177313 25576.492003299692 24627.945452856457 21037.891642389714 25005.386501240693 31018.367541786367 0.7988994354969499 0.7719417527540852 0.4867309842846402 0.8604546776870031 0.6546074967621569 0.8245595764781736 0.7939794194416886 0.6782398078831369 0.8061477273926395 1.0 14.920835140670642 -13.57026266726566 0.24958623946903224 1.9326651365195293 0.7122129736167763 0.3719448078207449 0.10293232765737677 114.40568086395915 1.7514843546555487 54.13769766054567 0.14747767692093916 2.689907418903866e-14 13.57026266726566 -1.220452162902753 TSPPLLDR ddPTM_PC-9_AZD4547_30min_R2 1 TSPPLLDR 8 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 100.19 0.022896 5731700.0 10303.0 12948.0 17459.0 17312.0 10892.0 16473.0 17067.0 17026.0 12414.0 12066.0 False True 13579.139684287018 17133.187788059677 17227.482252492046 13320.985867733745 9379.833809605467 15442.94070589912 18585.92993684002 14395.022918557737 13070.178696316712 11643.573012604567 1.1662347691372 1.4714716667738 1.4795700798923754 1.1440634119194615 0.8055803660484179 1.3263059963794281 1.5962393946188265 1.2363063213478054 1.122523016102342 1.0 13.507246219288273 -8.418928854416626 2.8092681477201586 1.0072932039425997 1.2837303098181687 0.15939907447447943 0.2090403625257579 0.5070450489839435 7.909560890644108 0.218218671119137 0.05908036979526212 3.811282542378614e-09 8.418928854416626 0.276437105875569 TSPS(ph)SPAPLPHQEATPR ddPTM_PC-9_Lapatinib_30min_R1 2 TSPSSPAPLPHQEATPR 17 0 P04920-2;P04920-3;P04920 P04920-2 SLC4A2 Anion exchange protein 2 1 T(0.017)S(0.017)PS(0.483)S(0.483)PAPLPHQEATPR;T(0.222)S(0.127)PS(0.37)S(0.281)PAPLPHQEATPR 151.63 2.3828000000000003e-05 19218100.0 21490.7 29650.0 15590.8 15864.6 14893.1 16448.5 18244.5 17145.7 22393.2 9454.8 True False 21184.23867708828 29581.34724669058 14308.984606228389 17031.335606754186 14017.117138961177 15745.035998326264 19189.110938975893 17942.351815455186 19871.042005150044 11089.04958227091 1.9103746015309988 2.66761790784893 1.2903706940859463 1.5358697317021432 1.2640503620230572 1.419872449979781 1.730455869694667 1.6180243114920583 1.7919517680685382 1.0 13.436848100170577 -5.269608929538501 24.999555695680918 1.4828592113369672 2.28899626857299 0.5838539817920398 0.2804782511120038 363.69280614999525 1112934.6950646744 0.07056330950866975 0.1510736856566317 5.375155968029846e-06 5.269608929538501 0.8061370572360229 TSPSGGTWSSVVSGVPRLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 TSPSGGTWSSVVSGVPRLSPK 21 1 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4 Q99700 ATXN2 Ataxin-2 1 TSPSGGTWSSVVSGVPRLS(1)PK;TSPSGGTWSSVVS(0.001)GVPRLS(0.999)PK 80.98100000000001 0.00038175 22199400.0 32155.0 24787.4 34512.0 65307.0 53996.0 43981.0 33280.0 33653.0 30557.0 42173.0 True False 42379.62113445102 32799.442305973935 34054.348330259774 50251.48013309193 46499.587438804345 41230.86111735257 36241.85552809727 28452.70211900761 32172.180636648092 40696.536106462154 1.0413569602972086 0.805951696237011 0.8367873924496568 1.2347851915856927 1.1425932496358266 1.0131294960704424 0.8905390727429127 0.6991430927825241 0.7905385498285568 1.0 15.31261838399925 -7.431962815685929 3.879208723591352 0.8061852325545454 1.010295253165978 0.26127993427664187 0.13812964763517294 0.32271993258908527 8.860283942647953 0.06838812507589948 0.043318358224723116 3.6985984584210746e-08 7.431962815685929 0.20411002061143246 TSPSGGTWSSVVSGVPRLS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSPSGGTWSSVVSGVPRLSPK 21 1 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4 Q99700 ATXN2 Ataxin-2 1 TSPSGGTWSSVVS(0.001)GVPRLS(0.999)PK 74.627 0.0007257 10110000.0 21893.0 36937.0 28348.0 38068.0 32614.0 46716.0 42301.0 56240.0 27869.0 24257.0 True False 25599.052493539843 40603.86125187119 29023.923830388696 35935.17337812122 26223.520821557933 44266.1307211821 38293.94304728103 54763.75959120562 28276.53140203192 28654.602081693665 0.8933661832245126 1.417010124101896 1.0128887411398038 1.2540803489670105 0.915159133838091 1.5448174989476486 1.3363976557100952 1.9111680362922263 0.9868059350960843 1.0 14.806479241646713 -6.770161533702836 24.999784417380525 1.4115708143489099 1.120082923052277 0.15047646062860764 0.2887602687008789 307.7593825142041 882106.7347230867 0.09472672585191808 0.08480483150629785 1.6976121165187466e-07 6.770161533702836 -0.2914878912966328 TSPSGGTWSSVVSGVPRLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 TSPSGGTWSSVVSGVPRLSPK 21 1 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A5F9ZHX3;A0A5F9ZHH4 Q99700 ATXN2 Ataxin-2 1 TSPSGGTWSSVVSGVPRLS(1)PK 121.56 7.8101e-07 8671800.0 29856.0 17287.0 17600.0 18730.0 17137.0 12751.0 11885.0 11825.0 17414.0 13154.0 True False 29430.247965080165 17246.973013610113 16152.995937964679 20107.466681448375 16129.035352638313 12205.669454032783 12500.347146248376 12374.432669284866 15452.651942450515 15427.651373396746 1.9076298298929237 1.117926027506078 1.0470158773368905 1.30333945166284 1.0454627838201624 0.7911553844858129 0.8102560035679716 0.8020943933580964 1.0016205038893269 1.0 13.91323082967242 -1.522878745280398 0.7660000771210714 0.9220423878771217 183.04579052680612 0.7821717700488567 0.14643941641396943 202.87782978604935 0.8186005146481244 0.05898944336607554 63882.83751764487 0.029999999999995825 1.522878745280398 182.123748138929 TSPSS(ph)PAPLPHQEATPR ddPTM_PC-9_AZD4547_30min_R2 2 TSPSSPAPLPHQEATPR 17 0 P04920-2;P04920-3;P04920 P04920-2 SLC4A2 Anion exchange protein 2 1 T(0.188)S(0.188)PS(0.238)S(0.386)PAPLPHQEATPR;T(0.008)S(0.002)PS(0.011)S(0.978)PAPLPHQEATPR 114.9 9.1e-05 25950000.0 20826.1 22026.7 28536.0 41063.0 29697.0 19852.6 29662.2 36265.0 29726.0 22563.5 True False 27448.36659020963 29146.400019404875 28157.59399490884 31596.559767025796 25574.084157533383 18611.21378364188 32302.078336704533 30661.07753679648 31297.255673168238 21773.558732794878 1.2606284037926916 1.3386144349249247 1.2932012786912257 1.451143570730848 1.174547737987095 0.8547621457768435 1.4835461089808815 1.4081794305225543 1.437397352322979 1.0 14.41028960455654 -11.764883568110116 2.1760641344548617 0.00021826684995828423 1.2973545945640015 0.2103493649976398 0.1744277841791944 2649911.005334931 655829.0264298312 12931721.666377699 0.0471949763279106 1.71836901040499e-12 11.764883568110116 1.2971363277140433 TSPSS(ph)PAPLPHQEATPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSPSSPAPLPHQEATPR 17 0 P04920-2;P04920-3;P04920 P04920-2 SLC4A2 Anion exchange protein 2 1 T(0.113)S(0.023)PS(0.142)S(0.722)PAPLPHQEATPR 104.45 0.00044633 8417400.0 4450.7 3806.0 4801.8 8447.4 12306.0 10068.0 11897.0 8019.2 3453.5 4099.8 True False 5204.11560466806 4183.834527022276 4916.2931229279075 7974.119564840315 9894.727639360155 9540.01635629895 10770.03003317895 7808.704497044738 3504.000904119892 4843.061286001057 1.074550846529784 0.8638822182811756 1.015120980842949 1.6465039556467373 2.0430729769951532 1.9698318466203417 2.2238062657414406 1.6123488917259663 0.7235095112771462 1.0 12.24170354414723 -5.7589128989440175 5.281393709199673 1.690922574468877 0.9639630503847479 0.28040666320108076 0.43905749974306735 0.1990828618533585 16.465554935850356 0.1274595177782956 0.2090982412815985 1.7421562410187622e-06 5.7589128989440175 -0.726959524084129 TSPTTPEASATNS(ph)PCTSKPATPAPSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSPTTPEASATNSPCTSKPATPAPSEK 27 1 Q12873;Q12873-3;Q12873-2 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 TSPTTPEAS(0.012)AT(0.012)NS(0.961)PCT(0.014)S(0.001)KPATPAPSEK;T(0.001)S(0.001)PT(0.006)T(0.019)PEAS(0.131)AT(0.131)NS(0.689)PCT(0.011)S(0.011)KPAT(0.001)PAPSEK 105.24 4.7743999999999996e-05 10036000.0 38146.0 44249.0 36749.0 37068.0 46093.0 32701.0 41353.0 31907.0 28391.0 25638.0 True False 44603.364382157364 48641.7482885467 37625.235531358594 34991.20013607744 37061.407531369034 30986.10199317955 37435.74447020671 31069.475058260963 28806.164664504955 30285.96644970368 1.4727403352384605 1.6060820898460257 1.2423323387696192 1.1553601960890965 1.223715531512505 1.0231174905591536 1.2360756105431459 1.0258703518627503 0.9511390271247823 1.0 14.886361829241066 -4.751614184970975 0.43272082851985605 1.0102088481318443 2.0054721422244572 0.7712860670740035 0.09660869519888439 2.5093319184117124 0.36053883154657085 0.07335457483932753 1.3044562774488753 1.7716821721330056e-05 4.751614184970975 0.9952632940926129 TSPTTPEASATNS(ph)PCTSKPATPAPSEK ddPTM_PC-9_Lapatinib_30min_R1 4 TSPTTPEASATNSPCTSKPATPAPSEK 27 1 Q12873;Q12873-3;Q12873-2 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 TSPTTPEAS(0.013)AT(0.035)NS(0.792)PCT(0.043)S(0.114)KPAT(0.002)PAPSEK;TSPTTPEAS(0.02)AT(0.074)NS(0.741)PCT(0.161)S(0.003)KPATPAPSEK;TSPT(0.001)T(0.001)PEAS(0.062)AT(0.249)NS(0.623)PCT(0.053)S(0.011)KPATPAPSEK;TSPTTPEAS(0.005)AT(0.019)NS(0.902)PCT(0.068)S(0.006)KPATPAPSEK 104.45 3.3037e-10 28931600.0 61072.2 117625.0 111157.0 113858.0 130796.0 130308.0 124949.0 137751.0 136241.0 108102.0 True False 60201.29922873015 117352.64653935842 102018.10053842845 122231.49713915384 123102.83643482998 124735.03060278446 131418.2478398477 144151.41434474938 120896.10389866776 126787.286663139 0.47482126018422427 0.925586859912481 0.8046398280411208 0.9640674578351894 0.9709399078939339 0.9838133923805217 1.0365254379882163 1.1369548015310487 0.9535349093783865 1.0 16.952050563860595 -4.397749792659719 0.7958147291278607 1.0195093121280328 1.0829840875041302e-29 0.7744208901916835 0.0806083407649608 2.0561616763609827 0.6554082954041471 0.029416938832598393 2.1380792270018656 4.0017523379416195e-05 4.397749792659719 -1.0195093121280328 down TSPTTPEASATNS(ph)PCTSKPATPAPSEKGEGIR ddPTM_PC-9_AZD4547_30min_R2 1 TSPTTPEASATNSPCTSKPATPAPSEKGEGIR 32 2 Q12873;Q12873-3;Q12873-2 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 TSPTTPEAS(0.156)AT(0.124)NS(0.522)PCT(0.098)S(0.098)KPAT(0.001)PAPSEKGEGIR 72.035 5.5835e-06 8535800.0 26631.0 17914.0 32550.0 58202.0 49885.0 32150.0 21230.0 31611.0 25791.0 37132.0 True False 35099.10404078885 23704.350172636805 32118.365732207814 44784.42811193618 42959.32882777899 30139.655417632282 23119.42887204041 26726.246298515747 27154.259606629934 35832.01998210119 0.9795457821892696 0.6615409955809803 0.8963593386097568 1.2498438026744485 1.1989089325479845 0.8411374919049398 0.6452170121469296 0.7458760715099523 0.7578210667496286 1.0 15.12896175538992 -6.9887030890436135 24.75464507861883 0.7627837639083611 0.990319391197205 0.24903857731844403 0.1727154581043784 286.9565400462463 628797.7075480634 0.06699180648950451 0.059031283503837025 1.026353366006564e-07 6.9887030890436135 0.2275356272888439 TSPTTPEASATNS(ph)PCTSKPATPAPSEKGEGIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSPTTPEASATNSPCTSKPATPAPSEKGEGIR 32 2 Q12873;Q12873-3;Q12873-2 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 TSPTTPEAS(0.049)AT(0.038)NS(0.609)PCT(0.132)S(0.132)KPAT(0.038)PAPS(0.001)EKGEGIR 71.882 5.994e-06 4583900.0 6767.0 2029.3 1741.2 10148.0 7860.2 11145.0 9570.7 10864.0 9136.0 6469.1 True False 7912.519445657708 2230.755492823518 1782.7168115377726 9579.440460259899 6320.05023491782 10560.536580348806 8664.094010132452 10578.831511359494 9269.596716386084 7641.896620632575 1.0354130444913991 0.29191123664256824 0.23328198483143106 1.2535422730524899 0.8270263978518285 1.38192612444352 1.1337622635119162 1.3843201546063062 1.2129968745401285 1.0 12.899715025750664 -5.771383748745916 24.99503782048924 1.1794899703367798 0.4973729917702341 0.5769908484892596 0.2548581188008709 130.1760233284031 327195.92906737095 0.07110768855098157 0.10689649983735844 1.6928413208584957e-06 5.771383748745916 -0.6821169785665457 TSPTTPEASATNSPCT(ph)SKPATPAPSEK ddPTM_PC-9_AZD4547_30min_R2 1 TSPTTPEASATNSPCTSKPATPAPSEK 27 1 Q12873;Q12873-3;Q12873-2 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 TSPTTPEAS(0.004)AT(0.017)NS(0.208)PCT(0.724)S(0.045)KPAT(0.002)PAPSEK 97.04899999999999 1.8574000000000002e-09 9321900.0 42160.0 48976.0 55780.0 53663.0 51876.0 59659.0 65111.0 67219.0 52701.0 55240.0 True False 55566.00301752314 64806.534222120135 55040.32075399543 41291.824435085226 44673.91284494063 55928.51329892762 70905.7528632794 56831.848088954204 55486.66726877608 53306.06441374743 1.0423955253239983 1.2157441172004209 1.0325339407311551 0.7746177642113872 0.8380643616492423 1.049196070166153 1.330162968193035 1.0661422619355385 1.040907219075552 1.0 15.702012051407179 -7.001957061368674 24.994298309349777 1.125509906287883 0.9810111644218862 0.1566819873259262 0.13887835095455636 144.40946263837458 1844324.26964904 0.05469597562901419 0.047518167071755414 9.955038378035518e-08 7.001957061368674 -0.14449874186599687 TSPTTPEASATNSPCT(ph)SKPATPAPSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSPTTPEASATNSPCTSKPATPAPSEK 27 1 Q12873;Q12873-3;Q12873-2 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 TSPTTPEAS(0.015)AT(0.015)NS(0.194)PCT(0.647)S(0.127)KPAT(0.003)PAPSEK 105.61 4.4196e-10 7160400.0 11466.0 15209.0 15815.0 15004.0 21727.0 15183.0 19251.0 14389.0 16520.0 11640.0 True False 13406.967336177217 16718.84900722066 16192.089578721496 14163.374523624316 17469.75031857453 14386.776751856076 17427.40591482962 14011.30399640572 16761.573747230523 13750.239857810702 0.9750351611911342 1.215895081111888 1.1775859727656839 1.0300456333915466 1.2705051329450805 1.046292784753409 1.2674255936655632 1.0189861516086007 1.219002280728162 1.0 13.747169164634444 -10.557854487513623 4.957311305631786 0.9999977318042107 1.1379134625514327 0.13125887610042497 0.10454053950911714 2.367210394558471e-06 4.6062373349820667e-07 0.09143053069322628 0.022174796453817282 2.7678688780461853e-11 10.557854487513623 0.13791573074722197 TSPTTPEASATNSPCT(ph)SKPATPAPSEK ddPTM_PC-9_Lapatinib_30min_R1 1 TSPTTPEASATNSPCTSKPATPAPSEK 27 1 Q12873;Q12873-3;Q12873-2 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 TSPTTPEAS(0.001)AT(0.003)NS(0.159)PCT(0.785)S(0.053)KPATPAPSEK 116.44 4.8041e-12 11367000.0 29736.0 46809.0 48881.0 47273.0 53568.0 55460.0 49151.0 53371.0 52885.0 52160.0 True False 29311.95918708547 46700.616636436396 44862.19286611657 50749.6141181051 50417.235558740074 53088.105083574475 51695.798282309945 55850.81150041463 46928.534396261355 61175.786501168805 0.4791431522752134 0.7633840005562356 0.7333325067305747 0.8295702764219548 0.8241371046006384 0.8677960369591683 0.8450369212878409 0.912956166069848 0.7671096209832097 1.0 15.900673123856434 -4.287512669749351 0.795631423556769 0.8645747414272609 3.830021211370342e-29 0.7497435181510019 0.06534169067732963 2.456985250235205 0.6887077882687592 0.022410741384060642 2.258109131023732 5.158071171210055e-05 4.287512669749351 -0.8645747414272609 down TSPTTPEASATNSPCT(ph)SKPATPAPSEKGEGIR ddPTM_PC-9_AZD4547_30min_R2 1 TSPTTPEASATNSPCTSKPATPAPSEKGEGIR 32 2 Q12873;Q12873-3;Q12873-2 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 TSPTTPEAS(0.095)AT(0.084)NS(0.066)PCT(0.247)S(0.247)KPAT(0.247)PAPS(0.012)EKGEGIR 57.351000000000006 0.00054329 6076900.0 7507.4 3301.0 7927.4 16313.0 13002.0 11004.0 7576.9 7571.1 6135.1 11250.0 True False 9894.597036379342 4367.983695426708 7822.277496328859 12552.289883337591 11196.896730856615 10315.91814045491 8251.229421599766 6401.160461570104 6459.3888609451105 10856.140924233492 0.9114285735083122 0.40235141805098795 0.7205394210448828 1.1562386644519225 1.0313882998573163 0.9502380461391511 0.7600517973362945 0.5896349822874157 0.5949986193092074 1.0 13.406223733253526 -11.177876571594403 5.153512173240247 1.0034518819206526 0.792972120444841 0.07772413784709564 0.2161072962483947 0.009609970166279534 0.0006433392794986246 0.23461009599505672 0.05606200396224707 6.639317359160014e-12 11.177876571594403 -0.2104797614758116 TSPTTPEASATNSPCT(ph)SKPATPAPSEKGEGIR ddPTM_PC-9_Lapatinib_30min_R1 1 TSPTTPEASATNSPCTSKPATPAPSEKGEGIR 32 2 Q12873;Q12873-3;Q12873-2 Q12873 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 TSPTTPEAS(0.219)AT(0.208)NS(0.122)PCT(0.361)S(0.088)KPAT(0.003)PAPSEKGEGIR 81.15100000000001 1.1305e-07 5454400.0 13667.0 6993.2 10922.0 9918.7 10028.0 10939.0 6479.2 6631.4 10377.0 7224.8 True False 13472.106073779156 6977.0076750609305 10024.035320139217 10648.154285813242 9438.172755806558 10471.164470054464 6814.661273030919 6939.5190531159105 9208.232985345634 8473.59705355913 1.5898922250640326 0.8233820455423245 1.1829728575456468 1.2566274061073912 1.1138330860141954 1.235740194378998 0.8042229563144716 0.8189578769503953 1.0866970575946773 1.0 13.048758810265733 -7.25440238865569 24.915770585054176 0.9123826267011774 1.1810981353734928 0.3238091768166306 0.19151526934610485 632.989700887352 2241222.9717112863 0.07116017865241926 0.05388922368007848 5.566697364127835e-08 7.25440238865569 0.2687155086723154 TSPYGS(ph)SLDLSTGSSSRPPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSPYGSSLDLSTGSSSRPPPK 21 1 J3KNZ9 J3KNZ9 FBRS 1 T(0.181)S(0.181)PY(0.04)GS(0.453)S(0.144)LDLSTGSSSRPPPK 63.906000000000006 0.022415 0.0 5995.5 5585.5 7018.1 10430.0 7967.6 7353.0 9006.1 7891.2 7976.4 5454.5 True False 7010.419733477285 6139.991526716483 7185.4381202924615 9845.640914516234 6406.405975895168 6967.395735783286 8152.977009482463 7684.0643614175215 8093.039760133743 6443.357672201757 1.088007230100228 0.9529180031718446 1.1151698362628888 1.5280295484748225 0.994265148981872 1.0813299664928364 1.2653305037925222 1.1925559238420802 1.2560283274431783 1.0 12.653596965963338 -5.5210333694143445 24.998619499335756 1.1972807206776992 1.023857897293353 0.16756695767610852 0.14840025372383991 108.12058980900737 1464666.6819246795 0.03976554048798871 0.07021687343176324 3.0127745260020455e-06 5.5210333694143445 -0.17342282338434623 TSPYGS(ph)SLDLSTGSSSRPPPK ddPTM_PC-9_Lapatinib_30min_R1 1 TSPYGSSLDLSTGSSSRPPPK 21 1 J3KNZ9 J3KNZ9 FBRS 1 T(0.141)S(0.044)PY(0.251)GS(0.282)S(0.282)LDLSTGSSSRPPPK 59.512 0.0053551 2442500.0 4057.9 6369.8 6182.8 5667.3 6654.6 6766.7 6472.9 6044.0 4445.8 3874.9 True False 4000.0336018722805 6355.051119459349 5674.474050298184 6084.092147558589 6263.189511446978 6477.30401494813 6808.03508985706 6324.826304706783 3945.067187650537 4544.671302020301 0.880159055748233 1.398352201320755 1.2485994416748332 1.3387309539534686 1.378139164577804 1.4252524736098497 1.498025849929036 1.391701596085756 0.868064360539515 1.0 12.149960238466784 -8.260880861299194 24.999709932032186 0.9340321433247849 1.3321327488090091 0.4709316678106459 0.16317075791102098 41.389658852678515 1852877.2908221774 0.12670773237769864 0.041200905015339524 5.484273927261373e-09 8.260880861299194 0.3981006054842242 TSQEGS(ph)SDDAER ddPTM_PC-9_AZD4547_30min_R2 1 TSQEGSSDDAER 12 0 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 TS(0.001)QEGS(0.821)S(0.178)DDAER 122.33 0.0017733 0.0 1178.4 807.89 1806.9 1036.1 3201.6 2668.2 1061.7 2120.8 995.69 2332.1 True False 1553.1066877573348 1069.0246433499797 1782.9393253925139 797.2431525854277 2757.1131036387133 2501.357032202998 1156.1892432145692 1793.0790911357506 1048.3201406585772 2250.4538888359943 0.6901304201174504 0.47502623744177797 0.7922576571052101 0.35425882598189423 1.2251364568348384 1.1114900174634454 0.5137582462587521 0.7967633107395893 0.46582609217592164 1.0 11.136000289274834 -6.236434426211943 24.988435946583376 0.838046805418502 0.5858788568477586 0.22530916718999539 0.24812315068535593 1378.5223292146995 1377611.858720464 0.07579412629499221 0.09781043642536918 5.801837674080796e-07 6.236434426211943 -0.2521679485707433 TSQEGSS(ph)DDAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSQEGSSDDAER 12 0 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 TSQEGS(0.361)S(0.639)DDAER;TSQEGS(0.304)S(0.696)DDAER 130.66 0.00013949 2949000.0 3414.0 2285.5 4919.5 4862.4 8160.6 5367.4 3390.2400000000002 5224.0 5208.5 3454.6 True False 3991.922770426393 2512.389335656704 5036.799537307643 4589.9754921134945 6561.589011357264 5085.924095232316 3069.091923987945 5086.8755352855305 5284.66445898609 4080.8916334014475 0.9781986705437462 0.6156471578645211 1.2342399626792933 1.1247481933960894 1.6078812183229036 1.2462776648134535 0.7520640584689671 1.2465108099539486 1.294977895451071 1.0 11.99466868552272 -5.274630862115551 24.737365196508133 1.1963422077380983 0.796922914757283 0.3319360751527497 0.22188305898955693 678.2355957262582 1271863.724227443 0.060053180574301 0.12623577982000775 5.313358726434164e-06 5.274630862115551 -0.39941929298081524 TSQEGSS(ph)DDAER ddPTM_PC-9_Lapatinib_30min_R1 2 TSQEGSSDDAER 12 0 P46100-4;P46100;P46100-2;P46100-5;P46100-3;A0A096LNW1;A0A096LNL9;P46100-6 P46100-4 ATRX Transcriptional regulator ATRX 1 TSQEGS(0.292)S(0.708)DDAER;T(0.053)S(0.009)QEGS(0.328)S(0.611)DDAER 150.12 0.00017062 2496100.0 3381.92 4975.110000000001 5227.14 4945.34 4294.8 6182.3 5618.3 5743.0 4563.8 4762.46 True False 3333.693200631827 4963.590438464849 4797.3847265439035 5309.03680077063 4042.1883079016757 5917.89744064519 5909.188083446975 6009.840745852264 4049.77678505545 5585.6448654209435 0.5968322872207155 0.8886333732373415 0.8588775051280251 0.9504787591558655 0.7236744199269908 1.0594832974937456 1.0579240581564702 1.0759439403420348 0.7250329877086183 1.0 12.447508134831452 -6.767416296438607 24.9999890468261 0.9930638083172203 0.8196377012150571 0.31845695280844366 0.13024859331295635 188.62082669711046 788949.8984455813 0.04508094079041729 0.04078193110210517 1.7083769516333094e-07 6.767416296438607 -0.17342610710216322 TSQLGDS(ph)PFYPGK ddPTM_PC-9_AZD4547_30min_R2 3 TSQLGDSPFYPGK 13 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 TSQLGDS(1)PFYPGK;T(0.017)S(0.002)QLGDS(0.964)PFY(0.017)PGK;T(0.045)S(0.032)QLGDS(0.921)PFY(0.003)PGK 132.31 5.7685e-05 43948900.0 109093.0 104221.0 128925.0 163450.0 153502.0 130754.0 107193.0 149178.0 104825.0 127257.0 True False 143782.3047246358 137908.40009726371 127215.37026190157 125769.12777732666 132190.8969373908 122577.93171001853 116732.96933964358 126125.96786941166 110365.8354955211 122801.77116401642 1.1708487863143062 1.123016376637358 1.0359408423514531 1.0241637932839502 1.0764575761764386 0.9981772294334507 0.9505805024891112 1.027069615314875 0.8987316261759316 1.0 16.90597184321588 -1.5228787452804167 0.3239071874379455 0.9637342923240824 3.1110164854697264 0.7193601006343895 0.03970535029251207 29.806583869264873 0.4250810960986349 0.036300901289928106 38.07106215753283 0.029999999999994535 1.5228787452804167 2.147282193145644 TSQLGDS(ph)PFYPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSQLGDSPFYPGK 13 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 TSQLGDS(1)PFYPGK;TSQLGDS(1)PFYPGK;TSQLGDS(1)PFYPGK 126.07 0.00013385 24168200.0 120276.0 124117.0 120496.0 132828.0 151247.0 110865.0 129908.0 112730.0 98484.0 89802.0 True False 140636.35124071626 136438.51549932294 123369.08162362453 125386.0777941862 121611.23608567426 105051.0442333218 117602.17378752718 109770.9569473079 99924.14218657707 106082.39172775898 1.3257275684510743 1.2861561026024695 1.16295531816655 1.1819688051148638 1.1463847496742647 0.9902778634829054 1.1085927821964234 1.0347707584592827 0.941948428566864 1.0 16.694825682289533 -5.010076714338607 0.35457315576852216 0.9748644269026638 1.562386567084275 0.8608660574188698 0.04516191540883965 1.929032300850104 0.21966971894223683 0.04397041856374235 0.48072292153201207 9.770646157550788e-06 5.010076714338607 0.5875221401816111 TSQLGDS(ph)PFYPGK ddPTM_PC-9_Lapatinib_30min_R1 2 TSQLGDSPFYPGK 13 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 T(0.003)S(0.002)QLGDS(0.994)PFYPGK;T(0.003)SQLGDS(0.997)PFYPGK 151.22 0.00013235 36919000.0 131011.0 120836.0 134543.0 113284.0 102713.0 109073.0 102587.0 89495.0 99321.0 81648.0 True False 129142.75911552475 120556.21166614168 123481.39389099927 121615.28326434594 96671.62328152757 104408.2020515817 107898.45289795402 93653.26441756028 88134.42308350325 95760.74801087877 1.3485980612938995 1.2589313906826005 1.2894781677871954 1.2699909492199246 1.0095119899287475 1.0903026993870237 1.1267503140816775 0.9779921978775784 0.9203606374658942 1.0 16.547146801122537 -6.265987398495666 0.610030097806987 0.9717788833088785 1.3601932510341466 0.8155392681620239 0.06216345287165725 0.42707216029488326 0.33208871988030125 0.04647111065123756 0.090841019348825 5.420166173471534e-07 6.265987398495666 0.38841436772526805 TSQLGDSPFY(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSQLGDSPFYPGK 13 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 T(0.035)S(0.014)QLGDS(0.453)PFY(0.498)PGK 69.672 0.043462 12460000.0 65120.0 54914.0 60407.0 72837.0 61923.0 63252.0 47434.0 43944.0 41040.0 37347.0 True False 76143.5298213728 60365.49900601712 61847.331974823246 68756.17903074005 49789.632667974896 59934.95377121779 42940.70812757923 42790.51656251669 41640.13235994799 44117.71546131066 1.7259173333249178 1.368282522674028 1.4018706845566538 1.5584709750221828 1.1285632573526674 1.3585235124828294 0.9733212084663899 0.9699168716032482 0.9438415367736934 1.0 15.42907046562898 -6.756143630159817 0.7258239341723566 0.9283963005974142 1.5451140282788225 0.7659838682878077 0.12761834413339423 0.32835105827591793 0.380033045328371 0.08949524890491539 0.09013809360140639 1.753300553221823e-07 6.756143630159817 0.6167177276814083 TSQVGAAS(ph)APAKESPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSQVGAASAPAKESPR 16 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 T(0.012)S(0.016)QVGAAS(0.634)APAKES(0.338)PR 99.81299999999999 0.008985799999999999 34289000.0 10126.0 7829.2 6710.6 10091.0 9066.4 10101.0 8745.3 10818.0 7606.9 6218.3 True False 11840.13180238361 8606.431234619762 6870.606154092224 9525.63398546341 7289.904003696965 9571.285778205764 7916.8818735109535 10534.038962618464 7718.136521659068 7345.628565964283 1.6118609450584602 1.1716398613588175 0.9353326393233304 1.2967758851298454 0.9924139150561581 1.3029907096792217 1.0777677910633208 1.434055488651791 1.0507115153386313 1.0 12.84267023224415 -4.76373007944483 6.164543939752882 1.149709448945888 1.6268843453711659 0.460540206191435 0.1530042015267165 0.11037275879038809 17.319621566913156 0.03572979606531922 0.2224638875746114 1.7229390748451005e-05 4.76373007944483 0.477174896425278 TSQVGAASAPAKES(ph)PR ddPTM_PC-9_AZD4547_30min_R2 10 TSQVGAASAPAKESPR 16 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 TSQVGAASAPAKES(1)PR;TSQVGAAS(0.007)APAKES(0.993)PR;TSQVGAASAPAKES(1)PR;TSQVGAASAPAKES(1)PR;TSQVGAASAPAKES(1)PR;TSQVGAASAPAKES(1)PR;TS(0.002)QVGAASAPAKES(0.998)PR;TSQVGAASAPAKES(1)PR;TSQVGAASAPAKES(1)PR;TSQVGAAS(0.001)APAKES(0.999)PR 193.27 4.3416e-39 683988600.0 459914.8 416037.5 516272.30000000005 694465.0 583548.6 560791.1 474040.89999999997 539281.1 491880.60000000003 572067.2999999999 True False 606158.1395778828 550513.4858182635 509426.19197567174 534366.8236272939 502532.9496720468 525724.7438654721 516229.6217610944 455947.59744185535 517880.4043218525 552039.3979507338 1.0980342015951166 0.9972358637116576 0.9228076725442973 0.9679867516901085 0.9103208059742411 0.9523319274259298 0.9351318468888787 0.8259330749479332 0.93812218157674 1.0 19.074411707382005 -1.5228802119323215 0.7784672930497837 0.9206087522427356 40.06817114842324 0.5779571585900738 0.04348929822507298 295.54109519154656 1.1305189732045626 0.015604847609868844 20357.771814720905 0.029999898687441226 1.5228802119323215 39.147562396180504 TSQVGAASAPAKES(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 TSQVGAASAPAKESPR 16 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 TSQVGAASAPAKES(1)PR;TSQVGAASAPAKES(1)PR;TSQVGAASAPAKES(1)PR;TSQVGAAS(0.001)APAKES(0.999)PR;TSQVGAASAPAKES(1)PR;TSQVGAASAPAKES(1)PR;TSQVGAASAPAKES(1)PR;TSQVGAASAPAKES(1)PR 206.7 2.4777e-16 2991655700.0 520115.0 520330.0 586048.0 652994.0 637664.0 616828.0 684501.0 661046.0 536726.0 437187.0 True False 608160.196760494 571984.9236588286 600021.6069194174 616408.8632151117 512718.31670932606 584480.4538163658 619660.1099219141 643694.2429361321 544574.6023641683 516445.5423296113 1.1775882390564767 1.1075416026996519 1.1618293851715837 1.1935602356728268 0.9927829261465356 1.1317368549254174 1.1998556655687582 1.246393259650418 1.054466652781377 1.0 18.97825670357917 -8.512488968266124 22.406263106085717 0.9999999874366429 1.1475634921380038 0.38534120015939943 0.06444513448264337 147.5578259261138 318217.0317163387 0.06487117764449732 0.016749666051975275 3.0726354138429805e-09 8.512488968266124 0.14756350470136093 TSQVGAASAPAKES(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 11 TSQVGAASAPAKESPR 16 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 TSQVGAASAPAKES(1)PR;TSQVGAASAPAKES(1)PR;TSQVGAASAPAKES(1)PR;TSQVGAASAPAKES(1)PR;TSQVGAASAPAKES(1)PR;TSQVGAASAPAKES(1)PR;TSQVGAAS(0.001)APAKES(0.999)PR;TSQVGAASAPAKES(1)PR;TSQVGAAS(0.041)APAKES(0.959)PR;TSQVGAAS(0.062)APAKES(0.938)PR;TSQVGAASAPAKES(1)PR 232.37 3.0993e-29 5115361100.0 1343810.3 1401876.0 1236500.7 1193316.2 1274629.3 1216762.7 1027612.9999999999 1020157.8999999999 1316253.0 1089603.7000000002 True False 1324647.3186973715 1398630.042253002 1134840.3854767298 1281076.65413415 1199658.1105916218 1164724.5957333883 1080817.7729909758 1067558.1603035147 1168002.7263814355 1277940.2477393348 1.0365487126965922 1.0944408744674616 0.8880230413622645 1.0024542668566574 0.9387435075417702 0.9114077108016404 0.8457498501224396 0.8353740812154682 0.9139728781902144 1.0 20.285388951535978 -5.329491985002848 0.7111976418680546 0.8904546598274597 1.1102870979846553 0.4368821449582344 0.06015329725992769 1.3852381826294404 0.8678715865378874 0.028011593680072108 0.21818559141548025 4.682825935488438e-06 5.329491985002848 0.21983243815719555 TSQVGAASAPAKES(ph)PRK ddPTM_PC-9_AZD4547_30min_R2 1 TSQVGAASAPAKESPRK 17 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 TSQVGAASAPAKES(1)PRK 80.719 0.0017785999999999998 196840000.0 530850.0 573780.0 734110.0 722880.0 772420.0 750080.0 660080.0 591900.0 748090.0 683500.0 True False 699649.2576340657 759243.1641205502 724375.2217410473 556231.184384668 665182.8159397206 703177.3790251194 718825.8412556036 500435.4555088889 787632.5101439968 659570.873041209 1.060764333646299 1.1511168778872287 1.0982522900094611 0.843322843866569 1.0085084759316851 1.066113450072235 1.0898386672855587 0.7587288583582169 1.194159024203585 1.0 19.331168164529913 -5.5605107940115435 24.999206012925605 0.9902606562794276 1.1106270131745595 0.1534108529051672 0.11704495670758577 264.0545975604061 175411.99915312216 0.030490603932816124 0.052811439947142436 2.7509912306467983e-06 5.5605107940115435 0.12036635689513187 TSQVGAASAPAKES(ph)PRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSQVGAASAPAKESPRK 17 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 TSQVGAASAPAKES(1)PRK;TSQVGAASAPAKES(1)PRK;TSQVGAASAPAKES(1)PRK 72.66199999999999 0.0037448 194440000.0 171722.0 179165.0 170833.0 228725.0 218494.0 208433.0 207771.0 234185.0 210448.0 168083.0 True False 200791.14293589987 196951.31713976507 174906.3066077602 215910.27978645533 175681.66917230314 197502.4065546739 188089.42674822386 228037.891889518 213525.40387149964 198555.11735570425 1.011261485525905 0.9919226447683742 0.8808954860348521 1.0874072784518565 0.884800510366982 0.9946981431904146 0.94729075358591 1.1484866012342378 1.0753961253437587 1.0 17.599180018318876 -7.748155945664764 24.93528791071197 1.083956032379117 0.9705597180826937 0.33761729258233186 0.0660082475792024 211.62824329184383 397264.40370958723 0.02941540725247745 0.016854013249927073 1.7858462013339497e-08 7.748155945664764 -0.11339631429642338 TSQVGAASAPAKES(ph)PRK ddPTM_PC-9_Lapatinib_30min_R1 1 TSQVGAASAPAKESPRK 17 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 TSQVGAASAPAKES(1)PRK 56.793 0.015249 46294000.0 91360.0 92112.0 78392.0 86068.0 93375.0 77023.0 66871.0 66894.0 79865.0 66601.0 True False 90057.18964662793 91898.72032334421 71946.91236187101 92397.72783443141 87882.86608231328 73728.9058393825 70333.25317768403 70002.13944855328 70869.76268426605 78112.89410974564 1.1529106772065187 1.1764859229800142 0.9210632019444619 1.182874209021319 1.1250750222983827 0.9438762534620238 0.900405163312327 0.8961662507370799 0.9072735492900409 1.0 16.25327309350905 -6.8074458570492045 5.39890244406349 0.918883111085397 1.1088649470552134 0.5988132193454131 0.07441934404709767 0.13585609561380588 8.972578348985081 0.026582592089056792 0.023847804134973387 1.557952250686849e-07 6.8074458570492045 0.18998183596981644 TSRPENAIIYNNNEDFQVGQAK ddPTM_PC-9_AZD4547_30min_R2 1 TSRPENAIIYNNNEDFQVGQAK 22 1 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 226.57 2.4074e-41 9933700.0 26435.0 24320.0 26813.0 36512.0 35181.0 31191.0 28944.0 39448.0 27189.0 34513.0 False True 34840.780117842114 32180.964396479096 26457.442100697037 28094.72250477669 30296.725418263843 29240.621839233845 31519.959928042277 33352.218024859976 28626.155032556395 33304.710374939605 1.0461216964690478 0.9662586473261728 0.794405410010866 0.843566035809661 0.9096828970193014 0.8779725603389779 0.9464114707257663 1.0014264543779405 0.8595227134626691 1.0 15.023438615524094 -7.357471986147846 6.777033778553602 0.9526299379717978 0.9013562626247089 0.08245261387623926 0.07339874272135896 0.6941932239386146 41.9383422730572 0.03278033305497248 0.02196686790452051 4.39064186246025e-08 7.357471986147846 -0.05127367534708893 TSRPENAIIYNNNEDFQVGQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSRPENAIIYNNNEDFQVGQAK 22 1 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 ; 176.39 8.7074e-13 21564000.0 76602.0 74702.0 84728.0 97702.0 102809.0 87910.0 87432.0 81983.0 91528.0 84114.0 False True 89569.20564153562 82117.9208716811 86748.23685272926 92228.07369415762 82664.31447058158 83299.84484328973 79149.80800713619 79831.03311816866 92866.42384603596 99363.20235394244 0.9014323564419799 0.8264419717388758 0.8730418786596942 0.9281914381707553 0.8319409249323746 0.8383369584503396 0.7965706230481183 0.8034265324279899 0.9346158501940763 1.0 16.60042405014591 -8.495634193396118 4.649799434678156 0.9996731936050989 0.8501558584541407 0.6102076859886777 0.039246375587563116 0.11615627765082785 6.852207046476462 0.040450443763768766 0.010546180262385931 3.194227222563947e-09 8.495634193396118 -0.14951733515095822 TSRPENAIIYNNNEDFQVGQAK ddPTM_PC-9_Lapatinib_30min_R1 4 TSRPENAIIYNNNEDFQVGQAK 22 1 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 ;;; 182.22 1.2369e-13 69845000.0 261194.0 237582.0 268137.0 231422.0 250419.0 213062.0 246774.0 223304.0 226137.0 228792.0 False True 257469.32566288643 237031.89347599464 246091.81089875253 248441.54588116138 235689.84676269648 203949.83493178058 259550.75024554424 233679.51905133054 200667.06973182084 268338.39235382347 0.9594949250623616 0.8833320174455359 0.917095048308491 0.925851659547745 0.878330695415073 0.7600471670966041 0.9672516406199076 0.8708389321465685 0.7478134901666508 1.0 18.033693956526655 -6.365292636628424 5.212079167662189 0.8626308506873699 0.9181869363050977 0.09432837062670552 0.07527160362710869 0.5367245544956968 21.901125402420202 0.023048196916920054 0.02622146513449887 4.312284082650888e-07 6.365292636628424 0.055556085617727846 TSS(ph)AELSTSAPDEPLLQK ddPTM_PC-9_AZD4547_30min_R2 2 TSSAELSTSAPDEPLLQK 18 0 Q15139 Q15139 PRKD1 Serine/threonine-protein kinase D1 1 T(0.157)S(0.033)S(0.758)AELS(0.049)T(0.003)SAPDEPLLQK;T(0.003)S(0.002)S(0.995)AELSTSAPDEPLLQK 246.95 1.6145999999999996e-53 5464300.0 22986.0 21852.0 28471.0 36199.0 29902.0 32856.0 22627.0 32161.0 19941.6 28346.0 True False 30295.069861498716 28915.231660849557 28093.45593737908 27853.879818974925 25750.623446090944 30801.509126025703 24640.75916569283 27191.25643625841 20995.672264416717 27353.61516785091 1.1075344036098358 1.0570899489305545 1.0270472756521674 1.0182887946640409 0.9413974455689504 1.1260489312662099 0.9008227619818774 0.9940644506915736 0.7675648039785699 1.0 14.73944389776138 -7.2843756620859805 24.907204651136997 0.9151183574238828 1.0398201784905603 0.4121719704048371 0.07618821489564957 803.9458437683207 873025.2042556888 0.030693973601140883 0.020708667156399053 5.195463976367046e-08 7.2843756620859805 0.12470182106667749 TSS(ph)DPNLNNHCQEVR ddPTM_PC-9_AZD4547_30min_R2 2 TSSDPNLNNHCQEVR 15 0 J3QR65;Q9NYA4 J3QR65 MTMR4 Myotubularin-related protein 4 1 TS(0.003)S(0.997)DPNLNNHCQEVR;T(0.005)S(0.024)S(0.971)DPNLNNHCQEVR 196.97 1.3382e-49 0.0 8426.099999999999 8708.7 10220.8 18373.4 12964.9 13184.1 9784.0 13372.400000000001 9341.8 11705.6 True False 11105.424526232247 11523.616967089545 10085.26551384792 14137.696496200278 11164.947425463997 12359.696142818224 10654.757045880524 11306.002847182046 9835.58847633731 11295.790506907344 0.9831471749977402 1.0201691470856233 0.8928339727689539 1.2515898278704016 0.9884166511973344 1.0941860275525033 0.9432502346219301 1.0009040837175989 0.8707304256681173 1.0 13.463497617123119 -7.2827625899072075 24.340982550967105 0.9537965127034049 1.0383653659246705 0.16510944937036132 0.09327385324530248 1125.5487083038752 1284835.4057614594 0.038426839391399674 0.025939848715018865 5.2147970370079814e-08 7.2827625899072075 0.08456885322126562 TSS(ph)DPNLNNHCQEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSSDPNLNNHCQEVR 15 0 J3QR65;Q9NYA4 J3QR65 MTMR4 Myotubularin-related protein 4 1 T(0.017)S(0.017)S(0.965)DPNLNNHCQEVR;T(0.37)S(0.106)S(0.523)DPNLNNHCQEVR 146.67 6.7064e-05 9424500.0 41989.0 59726.0 58857.0 62056.0 73654.0 51863.0 64797.0 55182.0 56215.0 49502.0 True False 49096.90837944751 65655.20256461705 60260.374096415486 58579.20350826649 59222.02742966293 49143.212980406475 58658.95907034514 53733.53097016195 57037.03802666851 58476.32074238364 0.8396032403567768 1.1227656208717345 1.03050898776432 1.0017593919141405 1.0127522846480796 0.8403950925179783 1.0031232869243965 0.9188938409255266 0.9753869139261366 1.0 15.83556492111166 TSS(ph)DPNLNNHCQEVR ddPTM_PC-9_Lapatinib_30min_R1 1 TSSDPNLNNHCQEVR 15 0 J3QR65;Q9NYA4 J3QR65 MTMR4 Myotubularin-related protein 4 1 T(0.001)S(0.023)S(0.977)DPNLNNHCQEVR 158.92 0.00014526 8175800.0 27663.0 23834.0 27236.0 25283.0 28912.0 25179.0 27910.0 27313.0 31223.0 20232.0 True False 27268.520547227094 23778.813837356593 24996.761214000348 27142.39616161553 27211.453003179016 24102.15286511576 29355.043235321195 28582.06169100869 27706.336947233962 23729.07424255458 1.1491607413122356 1.0020961456099629 1.0534233640338297 1.1438455577394444 1.146755778376693 1.0157224263680764 1.2370918028768807 1.2045165099509443 1.167611372615066 1.0 14.534368196401232 -6.214543924091588 0.9896145245813995 1.1504107793508231 1.0651232228517173 0.06035958461662971 0.08006762385625493 1.1550617957534406 2.3769444925010337 0.03675559263947119 0.060736737908762745 6.101773408230192e-07 6.214543924091588 -0.0852875564991058 TSS(ph)DPVLLK ddPTM_PC-9_AZD4547_30min_R2 4 TSSDPVLLK 9 0 Q9BRG2;Q9BRG2-2 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 TS(0.003)S(0.997)DPVLLK;T(0.218)S(0.032)S(0.75)DPVLLK;T(0.006)S(0.005)S(0.989)DPVLLK;T(0.007)S(0.021)S(0.971)DPVLLK 166.69 6.6791e-05 268183500.0 1280480.0 1270921.0 1480189.0 1929846.0 1863299.0 1664375.0 1591278.0 1712938.0 1448324.0 1575226.0 True False 1687646.0043614332 1681721.3590352626 1460560.72672169 1484949.8205234816 1604612.0967319151 1560301.3681406472 1732898.6592860462 1448242.7914993833 1524879.449827954 1520077.817201476 1.1102365847746247 1.1063389913362323 0.9608460239296437 0.97689065896464 1.0556118105098526 1.026461507749139 1.14000654418889 0.9527425340405639 1.0031588071164133 1.0 20.535713750635793 -5.229867539776709 21.372323710180236 1.0178166981985213 1.1082881550849055 0.3487889087535665 0.051116232659357254 137.0775293254914 92790.14353879011 0.013507035900595493 0.03571576131707665 5.890232806129167e-06 5.229867539776709 0.09047145688638425 TSS(ph)DPVLLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSSDPVLLK 9 0 Q9BRG2;Q9BRG2-2 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 TS(0.001)S(0.998)DPVLLK;TS(0.001)S(0.999)DPVLLK 180.09 0.0065656 29683000.0 232663.0 215810.0 217989.0 266870.0 279640.0 263740.0 275020.0 252270.0 247800.0 216919.0 True False 272048.2505962848 237234.19056139656 223186.68448788617 251918.13910421313 224846.54941253611 249909.01011226518 248968.1146276268 245648.17980215925 251423.60620845738 256244.69757014036 1.061673678230234 0.9258111204289792 0.870990450160611 0.9831155200206906 0.8774681058560838 0.9752748543952175 0.9716029911583955 0.9586468798439016 0.9811855956146631 1.0 17.96716262590988 TSS(ph)DPVLLK ddPTM_PC-9_Lapatinib_30min_R1 1 TSSDPVLLK 9 0 Q9BRG2;Q9BRG2-2 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 TS(0.002)S(0.998)DPVLLK 169.99 0.0018999000000000002 105080000.0 613310.0 608590.0 647430.0 567550.0 662900.0 601320.0 583220.0 555660.0 591770.0 470900.0 True False 604564.0869327192 607180.8472466596 594200.8045520717 609289.5202912983 623909.5253115452 575602.9453453838 613416.2778826229 581477.9921365598 525118.6309856408 552294.4375651901 1.0946409121880019 1.0993788927577075 1.0758768586763743 1.1031969160822495 1.129668312543709 1.0422030464093575 1.1106689406232129 1.0528405730465553 0.9507947125099524 1.0 19.075078071812243 -8.075607353601743 3.9696754453946923 0.9772361914636081 1.0926584682269442 0.7832995438801841 0.024558627880342746 0.09899668747038307 2.8783954350028473 0.0173660455553286 0.006172863909611408 8.402192869474603e-09 8.075607353601743 0.11542227676333616 TSS(ph)EDNLYLAVLR ddPTM_PC-9_AZD4547_30min_R2 11 TSSEDNLYLAVLR 13 0 Q15149-4 Q15149-4 PLEC Plectin 1 TS(0.001)S(0.999)EDNLYLAVLR;T(0.004)S(0.001)S(0.995)EDNLYLAVLR;T(0.319)S(0.047)S(0.634)EDNLYLAVLR;TS(0.014)S(0.986)EDNLYLAVLR;T(0.308)S(0.038)S(0.655)EDNLYLAVLR;TS(0.047)S(0.952)EDNLYLAVLR;T(0.013)S(0.001)S(0.985)EDNLYLAVLR;T(0.003)S(0.081)S(0.916)EDNLYLAVLR;T(0.376)S(0.083)S(0.541)EDNLYLAVLR;T(0.008)S(0.309)S(0.683)EDNLYLAVLR;T(0.208)S(0.026)S(0.766)EDNLYLAVLR 263.72 2.5855e-55 1148490400.0 2364135.5 2841465.7 4039042.4 4988986.0 4558881.600000001 4345369.4 4157412.1 5470592.1 4214667.6 4418299.0 True False 3115881.411926786 3759913.919634726 3985482.0587125784 3838852.356765332 3925959.5818645135 4073652.7644890635 4527413.722925596 4625237.7926454125 4437446.324921557 4263615.696835559 0.7308072850560576 0.881860417772953 0.9347657814635099 0.9003748531122342 0.9208052181575247 0.9554455781538929 1.0618719051733079 1.0848158280490074 1.0407707074103827 1.0 22.023645975231815 -3.1495089482211274 0.31081783148747644 1.0592831768302147 1.588092354080422e-11 0.7995690502726568 0.04424756290847768 9.670268954264886 0.3385736130493691 0.04972935529796072 4.717471157997339 0.0007087467032549082 3.1495089482211274 -1.0592831768143338 TSS(ph)EDNLYLAVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 12 TSSEDNLYLAVLR 13 0 Q15149-4 Q15149-4 PLEC Plectin 1 T(0.002)S(0.002)S(0.995)EDNLYLAVLR;TS(0.085)S(0.915)EDNLYLAVLR;T(0.002)S(0.002)S(0.997)EDNLYLAVLR;T(0.035)S(0.035)S(0.93)EDNLYLAVLR;T(0.326)S(0.05)S(0.624)EDNLYLAVLR;T(0.006)S(0.258)S(0.737)EDNLYLAVLR;T(0.016)S(0.016)S(0.968)EDNLYLAVLR;TS(0.006)S(0.994)EDNLYLAVLR;T(0.003)S(0.004)S(0.993)EDNLYLAVLR;T(0.012)S(0.189)S(0.799)EDNLYLAVLR;TS(0.029)S(0.971)EDNLYLAVLR;T(0.001)S(0.039)S(0.961)EDNLYLAVLR 252.52 5.381e-36 597317600.0 1253000.9000000001 1666564.2 1825822.2 2262504.1 2630614.7 2184419.6 2447985.5 2239012.7 2174973.2 1826344.8 True False 1465109.2044741586 1832009.679836906 1869356.7257172554 2135743.330414258 2115164.633560631 2069864.790725068 2216094.5915597654 2180240.989055048 2206778.068404959 2157446.654902514 0.679094058314207 0.8491564209357876 0.8664671830793071 0.9899402729430468 0.9804018230319611 0.9594048529643002 1.0271839567963275 1.0105654219077618 1.022865646939796 1.0 21.04089345704402 -3.956854854225294 0.5919613416405991 1.012465854753825 2.3067952245977934e-13 0.9418930426433094 0.02519668899023471 1.8546971693585528 0.23844134492074118 0.011818196437467126 1.5952795152117172 0.00011044476762343375 3.956854854225294 -1.0124658547535943 TSS(ph)EDNLYLAVLR ddPTM_PC-9_Lapatinib_30min_R1 9 TSSEDNLYLAVLR 13 0 Q15149-4 Q15149-4 PLEC Plectin 1 T(0.014)S(0.002)S(0.983)EDNLYLAVLR;T(0.024)S(0.004)S(0.972)EDNLYLAVLR;T(0.207)S(0.207)S(0.586)EDNLYLAVLR;T(0.059)S(0.059)S(0.881)EDNLYLAVLR;T(0.015)S(0.304)S(0.681)EDNLYLAVLR;T(0.326)S(0.05)S(0.624)EDNLYLAVLR;T(0.035)S(0.035)S(0.931)EDNLYLAVLR;T(0.001)S(0.038)S(0.961)EDNLYLAVLR;TS(0.012)S(0.988)EDNLYLAVLR 238.88 3.5463999999999996e-26 536250300.0 1753362.1 1637985.2 1816259.0 1713784.2 1965941.8 2098630.9000000004 1882466.5 1693311.4 2004040.2 1470986.4 True False 1728358.8349267675 1634192.5459069142 1666933.195982492 1839821.6070845004 1850308.9685142916 2008877.3485545714 1979931.4043906736 1771988.8293811795 1778324.0891971332 1725244.4392738307 1.0018051909526788 0.9472237722990482 0.9662011701275893 1.0664121356964906 1.0724909041255055 1.1644015785960882 1.1476236986012502 1.0270943577867864 1.0307664518227018 1.0 20.718369352284242 -5.803479184152649 4.550789616642428 1.0820087152079934 0.9684856161641783 0.4539107199560629 0.050184496432163495 0.17497339695968467 7.921037954900766 0.015266131230498152 0.024166140526491787 1.572247148871327e-06 5.803479184152649 -0.11352309904381508 TSS(ph)FTEQLDEGTPNR ddPTM_PC-9_AZD4547_30min_R2 2 TSSFTEQLDEGTPNR 15 0 Q13439-3;Q13439-4;Q13439;Q86W71;C9J0Y3;Q13439-5;E7EVX2;C9JHJ5 Q13439-3;Q13439-5 GOLGA4 Golgin subfamily A member 4 1 T(0.154)S(0.154)S(0.529)FT(0.163)EQLDEGTPNR;TS(0.002)S(0.956)FT(0.042)EQLDEGTPNR 279.19 2.9715e-75 180417000.0 44443.0 48253.0 58276.0 56107.0 58188.0 57023.0 60173.0 68497.0 52485.0 55963.0 True False 58574.94952817312 63849.83861115568 57503.22216313802 43172.39799450884 50109.60059799143 53457.3427956344 65528.28042945303 57912.36255447261 55259.24994974884 54003.75240381148 1.0846459166426186 1.182322260381471 1.0648004926242784 0.7994332999619823 0.9278910884432319 0.9898820066411068 1.213402356552323 1.0723766400792785 1.0232483390515055 1.0 15.720772034719761 -10.311640377710706 15.24397994433901 0.9999940922648254 1.0389445689946195 0.01102176905221719 0.11279164756211794 0.0 0.0 0.1215015610718372 0.029468457057448223 4.879323605862205e-11 10.311640377710706 0.038950476729794126 TSS(ph)FTEQLDEGTPNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSSFTEQLDEGTPNR 15 0 Q13439-3;Q13439-4;Q13439;Q86W71;C9J0Y3;Q13439-5;E7EVX2;C9JHJ5 Q13439-3;Q13439-5 GOLGA4 Golgin subfamily A member 4 1 T(0.01)S(0.052)S(0.648)FT(0.291)EQLDEGTPNR;T(0.019)S(0.003)S(0.901)FT(0.077)EQLDEGTPNR;T(0.003)S(0.005)S(0.95)FT(0.042)EQLDEGTPNR 287.43 3.3923e-89 103071000.0 77572.0 82080.0 91317.0 90183.0 111663.0 91330.0 123691.0 88797.0 101424.0 85838.0 True False 90703.4074831624 90228.35995217766 93494.34360165113 85130.338887231 89783.4367295525 86540.49402272367 111974.09303470927 86466.17283819866 102907.13412464323 101399.74990676591 0.8945131281542757 0.8898282297060889 0.9220372208769393 0.8395517638406983 0.8854404158995041 0.8534586535203007 1.1042837200058793 0.852725701174823 1.0148657587347436 1.0 16.62969456850673 -7.192597211299609 24.999997516005156 0.9806996861015905 0.8814247525564233 0.4401696735334243 0.06134585077653951 170.91028965326734 62065.677368783014 0.02210800305555698 0.017124782707241448 6.418045456388386e-08 7.192597211299609 -0.09927493354516725 TSS(ph)FTEQLDEGTPNR ddPTM_PC-9_Lapatinib_30min_R1 2 TSSFTEQLDEGTPNR 15 0 Q13439-3;Q13439-4;Q13439;Q86W71;C9J0Y3;Q13439-5;E7EVX2;C9JHJ5 Q13439-3;Q13439-5 GOLGA4 Golgin subfamily A member 4 1 TS(0.017)S(0.982)FT(0.001)EQLDEGTPNR;T(0.002)S(0.002)S(0.955)FT(0.042)EQLDEGTPNR 295.71 3.896799999999999e-104 147009000.0 66503.0 120077.0 133187.0 111486.0 165266.0 197394.0 188949.0 183234.0 172343.0 163645.0 True False 65554.65502484347 119798.96908400882 122236.87897668748 119685.05234639338 155545.37880545735 188951.91876788854 198731.85468544273 191747.72056860375 152931.91648775394 191930.82020674425 0.34155356057057035 0.6241778623931458 0.6368798864352074 0.6235843321956885 0.8104241863704162 0.9844792960523646 1.0354348221477536 0.9990460123186924 0.7968074972170628 1.0 17.550226872208853 -6.063400851633194 0.9199972821388898 0.9776757627093858 0.4648870245248877 0.8149771828159571 0.09283898546558941 0.2704990829012605 0.4705344801262953 0.044124788915383496 0.09111088335992001 8.641699260440469e-07 6.063400851633194 -0.5127887381844981 down TSS(ph)FTEQLDEGTPNRENASTHASK ddPTM_PC-9_AZD4547_30min_R2 1 TSSFTEQLDEGTPNRENASTHASK 24 1 Q13439-5;E7EVX2;C9JHJ5 Q13439-5 GOLGA4 Golgin subfamily A member 4 1 T(0.134)S(0.156)S(0.708)FT(0.003)EQLDEGTPNRENASTHASK 81.763 4.1633e-05 6017100.0 5934.2 4078.1 10535.0 24338.0 16474.0 10020.0 5332.7 13516.0 8388.9 10580.0 True False 7821.152160972144 5396.266073407957 10395.299016553286 18727.25011835165 14186.86946193908 9393.447816008571 5807.299969191234 11427.412766781776 8832.32012772122 10209.597420301368 0.7660588208326512 0.5285483698581201 1.01818892446069 1.8342789972416813 1.3895620833911697 0.9200605498244312 0.5688079294530903 1.1192814267151054 0.8650997452807013 1.0 13.317638359263153 -6.97334647641286 24.330365117721456 0.8762653333096025 1.1150276248967697 0.0837217416477678 0.35168571156301764 470.21391224569004 429227.23256950214 0.1410452128737156 0.12438654428202918 1.063294392609315e-07 6.97334647641286 0.2387622915871671 TSS(ph)FTEQLDEGTPNRESGDTQSFAQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSSFTEQLDEGTPNRESGDTQSFAQK 26 1 Q13439-3;Q13439-4;Q13439;Q86W71 Q13439-3 GOLGA4 Golgin subfamily A member 4 1 T(0.17)S(0.17)S(0.578)FT(0.08)EQLDEGT(0.001)PNRESGDTQSFAQK;T(0.2)S(0.2)S(0.577)FT(0.02)EQLDEGT(0.003)PNRES(0.001)GDTQSFAQK 67.055 0.0001942 14845900.0 12471.8 6056.9 8778.9 17889.1 21622.8 26323.0 16493.9 32449.0 23439.0 17158.2 True False 14583.0294107217 6658.189003342411 8988.222270163647 16886.83172424471 17385.967560568555 24942.57554100687 14931.478386505018 31597.24813255745 23781.75103276852 20268.845835763525 0.7194800103018475 0.32849374144404003 0.4434501275008125 0.8331422450531745 0.8577680101494357 1.2305868692827466 0.7366713678466612 1.558907122220321 1.1733155022969597 1.0 14.30697631964053 -6.260683288003173 1.1544191531443369 1.1720092116255731 0.4685580803673712 0.594733281980417 0.2230233357303784 0.3179779082752585 0.8756667794423887 0.09260897820025138 0.13711577462769808 5.48676945190439e-07 6.260683288003173 -0.7034511312582019 TSS(ph)IADEGTYTLDSILR ddPTM_PC-9_AZD4547_30min_R2 2 TSSIADEGTYTLDSILR 17 0 E7ERV5;A0A087WY00;G3V394;F8WE88;F8W6H6;Q9Y4I1-2;Q9Y4I1;Q9Y4I1-3 E7ERV5 MYO5A Unconventional myosin-Va 1 T(0.001)S(0.035)S(0.963)IADEGTYTLDSILR;T(0.005)S(0.018)S(0.977)IADEGTYTLDSILR 130.95 2.7085e-05 9334900.0 10215.099999999999 10255.900000000001 12151.900000000001 12315.5 11137.7 11097.4 11590.0 15686.2 14787.5 11979.4 True False 13463.289312720593 13570.919109944498 11990.757866089598 9476.351747578265 9591.422605696183 10403.477823689962 12621.487547194929 13262.258223016586 15569.137060720412 11560.004852245573 1.1646439153617916 1.1739544475457808 1.0372623557991283 0.8197532672953376 0.8297074895978971 0.8999544512880588 1.0918237239963753 1.147253689987885 1.346810599105938 1.0 13.496854382951117 -10.339253391612704 8.96594786013729 0.999999984662861 1.0450941542778802 0.006564606688228891 0.15901162164382313 0.0 0.0 0.17223847410599016 0.04177396597260059 4.57874659161674e-11 10.339253391612704 0.04509416961501922 TSS(ph)IADEGTYTLDSILR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSSIADEGTYTLDSILR 17 0 E7ERV5;A0A087WY00;G3V394;F8WE88;F8W6H6;Q9Y4I1-2;Q9Y4I1;Q9Y4I1-3 E7ERV5 MYO5A Unconventional myosin-Va 1 T(0.253)S(0.027)S(0.72)IADEGTYTLDSILR;T(0.003)S(0.011)S(0.986)IADEGTYTLDSILR;T(0.001)SS(0.999)IADEGTYTLDSILR 127.3 3.4631999999999996e-05 5075680.0 12683.900000000001 13983.3 11572.5 14087.1 19646.9 17911.5 22053.6 16567.6 18764.5 15471.5 True False 14831.033751555762 15371.46961158976 11848.432288950651 13297.845457994406 15797.230981451732 16972.18940860634 19964.523353762735 16132.71805482322 19038.895313553705 18276.3604776734 0.8114872635431718 0.8410574758780729 0.6482927661349657 0.7275981163886103 0.8643532174116286 0.9286416422645938 1.0923686572144171 0.8827095566719164 1.0417224663965141 1.0 14.157691182790796 -6.648991612525852 2.285516312628262 0.9941046662720754 0.757063176650573 0.7082815340766941 0.07068046731299274 0.171372563428119 1.8278307967576568 0.026867687425645735 0.026632342543853216 2.2439252600077275e-07 6.648991612525852 -0.2370414896215024 TSS(ph)IADEGTYTLDSILR ddPTM_PC-9_Lapatinib_30min_R1 2 TSSIADEGTYTLDSILR 17 0 E7ERV5;A0A087WY00;G3V394;F8WE88;F8W6H6;Q9Y4I1-2;Q9Y4I1;Q9Y4I1-3 E7ERV5 MYO5A Unconventional myosin-Va 1 TS(0.345)S(0.654)IADEGTYTLDSILR;T(0.001)S(0.052)S(0.947)IADEGTYTLDSILR 183.76 3.9019e-08 4914100.0 4665.8 6168.1 7029.5 6235.4 7566.200000000001 9172.400000000001 10928.4 9991.6 7639.700000000001 7891.4 True False 4599.264836397074 6153.818143416931 6451.561644654703 6693.972116684631 7121.170991721539 8780.11783390873 11494.21907892813 10455.846212129114 6779.236536392511 9255.417975370461 0.4969267566992815 0.6648881941142821 0.6970578381033591 0.7232490347273264 0.7694056617077312 0.9486462801867457 1.2418908697062985 1.1297000567616833 0.7324614138910526 1.0 13.176082428445453 -6.644097294848906 1.9788066567274996 1.042170030724259 0.6472126757781707 0.6309545927518231 0.13334662624072688 0.21866513521559902 1.7539429092752576 0.053471051722863365 0.05324276110866671 2.269356391770228e-07 6.644097294848906 -0.3949573549460883 TSS(ph)IATALNTSGAGGSRPAQAVR ddPTM_PC-9_AZD4547_30min_R2 1 TSSIATALNTSGAGGSRPAQAVR 23 1 Q8N4C8;Q8N4C8-4;Q8N4C8-3;Q8N4C8-2;Q8N4C8-5 Q8N4C8;Q8N4C8-3 MINK1 Misshapen-like kinase 1 1 T(0.061)S(0.061)S(0.338)IAT(0.096)ALNT(0.326)S(0.118)GAGGS(0.001)RPAQAVR 81.788 0.00060852 7227400.0 6215.5 6557.9 9957.9 13903.0 15218.0 13852.0 9383.2 12783.0 10301.0 15105.0 True False 8191.899709568661 8677.612928275921 9825.85173962373 10697.878149208767 13105.243381800958 12985.832250234593 10218.286622333006 10807.681074117452 10845.489830091707 14576.17854760418 0.5620059937393622 0.5953283914529313 0.6741034152081486 0.7339288630604164 0.899086364714914 0.89089415362362 0.7010264445486323 0.7414619022963231 0.7440557752960792 1.0 13.831324915877069 -5.648064473358462 1.8482510807877015 0.8123171215257414 0.5763879614743224 0.5718030473781845 0.08586756288803399 0.2815440648771111 1.930858094877206 0.027024137072856485 0.0629017530236226 2.2487207463301754e-06 5.648064473358462 -0.23592916005141906 TSS(ph)IATALNTSGAGGSRPAQAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSIATALNTSGAGGSRPAQAVR 23 1 Q8N4C8;Q8N4C8-4;Q8N4C8-3;Q8N4C8-2;Q8N4C8-5 Q8N4C8;Q8N4C8-3 MINK1 Misshapen-like kinase 1 1 T(0.175)S(0.175)S(0.647)IAT(0.002)ALNTSGAGGSRPAQAVR 66.77 0.00074138 24110000.0 6435.6 2304.5 5847.1 6845.8 7389.6 5835.9 7452.8 7872.6 5433.4 2740.2 True False 7525.01997110606 2533.2755300900767 5986.517039250233 6462.252020383057 5941.660926687456 5529.8551304852 6746.816830400613 7665.9525917092 5512.853196017086 3236.976568588736 2.3247063460786292 0.7826054580291694 1.8494162414837152 1.996385170993216 1.8355588311465332 1.7083395611035017 2.0842958506005203 2.368244696640303 1.7030871491357726 1.0 11.660431207050946 -5.481315844703702 24.982835901237447 1.8819225705001683 1.494244633022667 0.030565669596696043 0.4825674046027017 1086.9651153851644 653356.4914101299 0.11770639448404926 0.2449847075304159 3.301293640595865e-06 5.481315844703702 -0.38767793747750123 TSS(ph)ISGPLSPAYTGQVPYNYNQLEGR ddPTM_PC-9_AZD4547_30min_R2 1 TSSISGPLSPAYTGQVPYNYNQLEGR 26 0 Q01082-3 Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 T(0.128)S(0.128)S(0.617)IS(0.128)GPLSPAYTGQVPYNYNQLEGR 203.26 6.586499999999999e-38 22534000.0 12625.0 17026.0 23638.0 29345.0 25140.0 29501.0 21969.0 34115.0 24048.0 25535.0 True False 16639.487383686665 22529.321538423235 23324.54467520517 22579.963625730506 21649.744947987634 27656.297806394075 23924.198440407738 28843.31063471146 25319.128185034962 24641.02742224911 0.6752757138958573 0.9143012242290208 0.94657354482487 0.9163564180502632 0.8786056107562886 1.1223678839552929 0.9709091277097429 1.17054009723101 1.0275191756888178 1.0 14.588774790861544 -3.6484419726309123 0.4148841380675599 1.063415144552773 3.751109921860688e-15 0.6257865281457555 0.07947411880203525 9.09027483559675 0.591026211341859 0.05818101054246138 5.807913929775485 0.00022467669531095493 3.6484419726309123 -1.0634151445527693 TSS(ph)LDGAAVAVLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSLDGAAVAVLSR 14 0 D6R9V6;A6NJ38;A6NHM7;Q7Z5H3-4;Q7Z5H3-3;Q7Z5H3;Q7Z5H3-5;Q7Z5H3-2 D6R9V6 ARHGAP22 Rho GTPase-activating protein 22 1 TS(0.012)S(0.988)LDGAAVAVLSR 124.2 3.8867e-05 1320100.0 7118.6 6350.4 7942.4 7844.5 9663.3 6214.3 9042.1 9463.5 7851.8 5074.2 True False 8323.638381241168 6980.825743668485 8131.776937719738 7404.9980972121375 7769.84573357947 5888.411168350071 8185.566828865038 9215.09315240708 7966.617720853791 5994.112292654901 1.3886357103187466 1.1646137747907541 1.3566273937984614 1.2353786074855682 1.296246275382683 0.9823658418220903 1.3656011814953006 1.53735744385355 1.3290738197574261 1.0 12.54933039596417 TSS(ph)LDTITGPYLTGQWPR ddPTM_PC-9_AZD4547_30min_R2 2 TSSLDTITGPYLTGQWPR 18 0 Q86VQ1;H7C0Q2;H7C2L5 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 T(0.01)S(0.016)S(0.974)LDTITGPYLTGQWPR;TS(0.013)S(0.985)LDT(0.001)ITGPYLTGQWPR 232.78 3.817e-43 35466000.0 21265.1 25229.7 39594.0 42185.0 38156.0 34898.0 34915.0 40956.0 32776.0 32295.1 True False 28026.959458442394 33384.70713132605 39068.95768973996 32459.900001752998 32858.69802050185 32715.822543220267 38022.367360682576 34627.19127525263 34508.4724464698 31164.458378863405 0.8993244521602548 1.0712429757472852 1.2536382700697795 1.0415679171170258 1.0543644821623956 1.0497799174141604 1.2200554522221505 1.1111116020144842 1.107302171818728 1.0 14.927614019270239 TSS(ph)LDTITGPYLTGQWPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSSLDTITGPYLTGQWPR 18 0 Q86VQ1;H7C0Q2;H7C2L5 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 T(0.007)S(0.034)S(0.959)LDTITGPYLTGQWPR;T(0.037)S(0.118)S(0.835)LDT(0.009)ITGPYLTGQWPR;T(0.202)S(0.015)S(0.783)LDTITGPYLTGQWPR 291.06 1.7860999999999995e-106 18959700.0 76411.0 103058.0 96756.0 109037.0 112490.0 90999.0 99279.0 91961.0 84747.0 77163.0 True False 89345.87311395747 113288.91715340535 99063.0299891735 102928.01039272375 90448.39201622162 86226.85224541603 89874.57440228392 89547.12119073383 85986.26454942755 91152.04107802798 0.9801851067435298 1.2428566142191786 1.0867889387619258 1.1291904073175423 0.9922804903380713 0.9459673225704744 0.9859853201240933 0.9823929352726144 0.9433279116133184 1.0 16.47598734102703 -6.315097586239839 4.6271563653683225 0.9714658935405133 1.1179981234154246 0.5308064032109665 0.062005014590963824 0.15326239954806728 7.101156688014628 0.018346620033482964 0.02130941681750672 4.840635859744727e-07 6.315097586239839 0.14653222987491132 TSS(ph)LDTITGPYLTGQWPR ddPTM_PC-9_Lapatinib_30min_R1 1 TSSLDTITGPYLTGQWPR 18 0 Q86VQ1;H7C0Q2;H7C2L5 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 TS(0.002)S(0.998)LDTITGPYLTGQWPR 281.49 1.8886999999999995e-92 14201000.0 14431.0 16944.0 15226.0 17618.0 17440.0 15266.0 13188.0 15382.0 13437.0 10774.0 True False 14225.211293678714 16904.76720903626 13974.17705405968 18913.686491925106 16414.21348835923 14613.10876678413 13870.810110620416 16096.703874751782 11923.583562117119 12636.271544547402 1.1257443497893922 1.3377970827423957 1.1058781860452809 1.496777465191972 1.2989760017813183 1.1564414958374125 1.0976980086033148 1.273849158591212 0.9435998205706643 1.0 13.625283224577089 -8.262290768214587 24.993704846380524 0.9717998777117193 1.2391017864112113 0.44493662744620543 0.11829898839585924 69.91076712603987 2052139.953123085 0.09590914546227641 0.03030971843420019 5.466498481301436e-09 8.262290768214587 0.267301908699492 TSS(ph)LDTLAAPYLAGHWPR ddPTM_PC-9_AZD4547_30min_R2 1 TSSLDTLAAPYLAGHWPR 18 0 Q6P1L5;Q6P1L5-2 Q6P1L5 FAM117B Protein FAM117B 1 T(0.252)S(0.252)S(0.354)LDT(0.143)LAAPYLAGHWPR 145.17 9.6785e-05 7644100.0 13196.0 15290.0 20806.0 28193.0 23377.0 22596.0 18426.0 25932.0 21191.0 21744.0 True False 17392.053506148844 20232.193487753517 20530.09884560109 21693.539427507927 20131.507066392493 21183.068547957046 20065.878304108184 21924.805258078213 22311.112997716085 20982.749178358496 0.8288739172504108 0.9642298688210457 0.9784275011386846 1.0338749819247965 0.9594313354875361 1.0095468600370612 0.9563035869867821 1.0448966945042335 1.063307424974019 1.0 14.356916093029156 -3.93974920035874 1.1403074196916028 1.0076350981189726 9.391636621359665e-17 0.7259019301798637 0.03280026979569019 4.9932348694097355 1.308554734902548 0.010206906440522873 9.538845207216196 0.00011488168573657207 3.93974920035874 -1.0076350981189726 TSS(ph)LDTLAAPYLAGHWPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSLDTLAAPYLAGHWPR 18 0 Q6P1L5;Q6P1L5-2 Q6P1L5 FAM117B Protein FAM117B 1 T(0.008)S(0.17)S(0.822)LDT(0.001)LAAPYLAGHWPR 116.0 0.00093999 0.0 6522.8 6631.8 7868.4 6836.8 7918.4 7316.5 7359.7 7038.8 7608.2 6493.3 True False 7626.9812088275585 7290.161275960679 8056.012497073175 6453.756261204659 6366.846362710018 6932.809860037871 6662.535936386237 6854.038958225073 7719.455531699712 7670.483889065485 0.9943285611615793 0.9504173897494306 1.0502613151377937 0.8413753753403603 0.8300449430297556 0.903829531526793 0.8685939547938939 0.8935601791688423 1.006384426764006 1.0 12.9051018770363 -5.761841629854496 24.999995018836014 0.8969747448128059 0.9935439154331926 0.3218744261698472 0.0600808508997049 11.975389557524217 744368.6585586894 0.01666550694949897 0.026560492596137197 1.7304472703494334e-06 5.761841629854496 0.09656917062038672 TSS(ph)LTQFPPSQSEER ddPTM_PC-9_AZD4547_30min_R2 10 TSSLTQFPPSQSEER 15 0 B7Z7F3;Q9H6Z4-3;Q9H6Z4-2;Q9H6Z4 B7Z7F3 RANBP3 Ran-binding protein 3 1 T(0.001)S(0.003)S(0.976)LT(0.02)QFPPSQSEER;T(0.044)S(0.078)S(0.879)LTQFPPSQSEER;T(0.352)S(0.056)S(0.59)LT(0.002)QFPPSQSEER;T(0.04)S(0.005)S(0.955)LTQFPPSQSEER;T(0.005)S(0.229)S(0.766)LTQFPPSQSEER;T(0.001)SS(0.541)LT(0.458)QFPPSQSEER;TS(0.004)S(0.996)LTQFPPSQSEER;T(0.058)S(0.325)S(0.578)LT(0.038)QFPPSQSEER;TS(0.002)S(0.919)LT(0.079)QFPPSQSEER;T(0.314)S(0.043)S(0.6)LT(0.043)QFPPSQSEER 275.76 9.927999999999997e-110 74042000.0 294051.5 269136.8 350493.6 489792.0 430793.0 374755.4 296693.2 392081.0 309422.6 349627.3 True False 387553.76034884324 356130.0073430234 345845.8258555497 376878.0216109657 370984.827978458 351321.8855955505 323098.3200291135 331493.89057506353 325778.04693724186 337386.9546452671 1.1486921916003603 1.0555535785829744 1.02507171985703 1.1170497745154966 1.0995826094358514 1.0413025185426472 0.9576491194474995 0.9825332189372893 0.9655917113919505 1.0 18.36404466610488 -7.056091216754571 3.5937239645250507 0.975496618746416 1.0848536172806036 0.7189591220173455 0.03309958883713778 0.13771823915839 3.5516429843543857 0.013530958423483874 0.010634191823703705 8.788379113047546e-08 7.056091216754571 0.10935699853418757 TSS(ph)LTQFPPSQSEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 13 TSSLTQFPPSQSEER 15 0 B7Z7F3;Q9H6Z4-3;Q9H6Z4-2;Q9H6Z4 B7Z7F3 RANBP3 Ran-binding protein 3 1 T(0.226)S(0.226)S(0.545)LT(0.004)QFPPSQSEER;T(0.001)S(0.096)S(0.897)LT(0.006)QFPPSQSEER;T(0.181)S(0.261)S(0.557)LTQFPPSQSEER;T(0.001)S(0.005)S(0.965)LT(0.029)QFPPSQSEER;T(0.001)S(0.054)S(0.862)LT(0.082)QFPPSQSEER;TS(0.003)S(0.997)LTQFPPSQSEER;T(0.001)S(0.006)S(0.993)LTQFPPSQSEER;TS(0.003)S(0.982)LT(0.015)QFPPSQSEER;TS(0.004)S(0.957)LT(0.039)QFPPSQSEER;T(0.15)S(0.028)S(0.813)LT(0.007)QFPPS(0.002)QSEER;T(0.027)S(0.005)S(0.966)LT(0.002)QFPPSQSEER;T(0.035)S(0.035)S(0.929)LT(0.001)QFPPSQSEER;T(0.008)S(0.063)S(0.815)LT(0.115)QFPPSQSEER 241.27 1.3141e-32 82490900.0 170649.2 187315.3 192877.60000000003 252297.4 345254.0 366288.9 413731.0 405937.8 353371.7 317973.0 True False 199536.7390846657 205910.7250603086 197476.53347637123 238161.99463720722 277603.9571265767 347080.06526924367 374539.4045269525 395282.36287665094 358539.09259892354 375618.98782711744 0.5312211191424235 0.5481904049937997 0.5257362909653063 0.634052064340325 0.7390573057354246 0.9240216190268605 0.9971258553610132 1.0523492573239768 0.9545286692587142 1.0 18.518910468609604 -6.556303892744788 1.3177218795985188 1.0120229188532648 0.5341808667761646 0.9818327108663811 0.02772286020736266 0.04918356266674648 0.17760235734899935 0.011903903086355623 0.012927753923499303 2.7777688746069256e-07 6.556303892744788 -0.4778420520771002 TSS(ph)LTQFPPSQSEER ddPTM_PC-9_Lapatinib_30min_R1 9 TSSLTQFPPSQSEER 15 0 B7Z7F3;Q9H6Z4-3;Q9H6Z4-2;Q9H6Z4 B7Z7F3 RANBP3 Ran-binding protein 3 1 T(0.007)S(0.035)S(0.954)LT(0.004)QFPPSQSEER;TS(0.003)S(0.997)LTQFPPSQSEER;T(0.001)S(0.023)S(0.722)LT(0.255)QFPPSQSEER;T(0.001)S(0.034)S(0.956)LT(0.01)QFPPSQSEER;T(0.028)S(0.038)S(0.931)LT(0.002)QFPPSQSEER;TS(0.015)S(0.928)LT(0.057)QFPPSQSEER;T(0.001)S(0.077)S(0.764)LT(0.158)QFPPSQSEER;T(0.004)S(0.225)S(0.77)LT(0.001)QFPPSQSEER;TS(0.003)S(0.988)LT(0.009)QFPPSQSEER 204.67 2.0571e-14 63752200.0 195876.7 192413.0 223473.0 209615.0 360508.0 419488.0 416047.0 427526.0 469976.0 385883.0 True False 193083.46233861236 191967.47952031923 205099.91257072598 225030.78635514103 339303.62822599825 401547.476114289 437587.877926394 447390.4187203967 417042.35381331784 452582.36239322193 0.4266261312473631 0.4241603196934354 0.45317698967801767 0.49721510393201124 0.7497058136154177 0.887236245776207 0.966869048127421 0.9885281793895577 0.9214728378013426 1.0 18.787820836806425 -6.446503228298471 1.4689048511986535 0.9695447117495216 0.4238757828425763 0.9914443206287235 0.022160455846499064 0.031746445792923 0.13909401922737136 0.008691630182803818 0.010253353821846752 3.5768174176371177e-07 6.446503228298471 -0.5456689289069453 down TSS(ph)NASTISGR ddPTM_PC-9_AZD4547_30min_R2 1 TSSNASTISGR 11 0 Q12778 Q12778 FOXO1 Forkhead box protein O1 1 T(0.305)S(0.038)S(0.653)NAS(0.002)T(0.002)ISGR 113.95 0.0025693 0.0 15736.0 13988.0 14135.0 18238.0 15903.0 16802.0 14970.0 17439.0 16736.0 15799.0 True False 20739.72067086679 18509.34744975122 13947.560664355064 14033.510874291116 13695.142955761641 15751.36828388982 16302.300999267321 14744.203258353607 17620.630792778837 15245.881818841332 1.360349038337422 1.214055550848938 0.9148411899086242 0.9204787916529741 0.8982847380357337 1.0331556069406096 1.069292100842631 0.9670941591671179 1.155763307242925 1.0 13.896131977511205 -5.059010936700052 3.6919105003678068 0.9923370998290468 1.3412967329691292 0.72020140251028 0.07525300432878577 0.11769823062122979 3.120024763665512 0.020610082599213892 0.07427171903554824 8.729493849041063e-06 5.059010936700052 0.3489596331400824 TSS(ph)NASTISGR ddPTM_PC-9_Lapatinib_30min_R1 1 TSSNASTISGR 11 0 Q12778 Q12778 FOXO1 Forkhead box protein O1 1 T(0.012)S(0.058)S(0.9)NAS(0.018)T(0.012)ISGR 101.38 0.009331 0.0 7982.8 10993.0 10397.0 12267.0 14902.0 14740.0 13278.0 12319.0 13391.0 13090.0 True False 7868.963808133768 10967.546383907906 9542.198793580614 13169.1561015124 14025.493658459247 14109.604560618234 13965.469870247021 12891.38571272054 11882.764566518601 15352.589058671378 0.5125496278224979 0.7143776428844923 0.6215367816538432 0.8577807984819511 0.9135588534845485 0.9190374670159567 0.9096491684156106 0.8396880593530436 0.7739909223849794 1.0 13.906194351570596 -5.7886133069774255 4.812464440546292 0.8864732876031304 0.6236999816330334 0.7530321702526291 0.0713443243809933 0.09407791315634402 5.3004314411099225 0.02001503594646818 0.031882667525056994 1.6269967785011928e-06 5.7886133069774255 -0.26277330597009696 TSS(ph)PLFNK ddPTM_PC-9_AZD4547_30min_R2 2 TSSPLFNK 8 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 T(0.013)S(0.023)S(0.965)PLFNK;T(0.003)S(0.019)S(0.979)PLFNK 128.28 0.0034216 84723000.0 288640.0 286730.0 402600.0 481370.0 425880.0 364140.0 370320.0 413350.0 362730.0 388360.0 True False 380421.5159150346 379409.8651892456 397261.26094583265 370397.583592363 366753.913223906 341370.2682356642 403277.7625951012 349476.2553380616 381903.16727202846 374763.63460758433 1.0150971993677418 1.0123977626231702 1.0600315085582026 0.9883498541159336 0.9786272715812854 0.9108948593507841 1.076085631994081 0.9325244582602012 1.0190507616138367 1.0 18.515621441530335 -5.89557593916658 8.892885795162876 0.9835568809103729 1.027396518180287 0.1625871858907011 0.04409403152125484 0.4634269629495783 35.95068702130245 0.011910410190914118 0.01770527530726607 1.271815345598015e-06 5.89557593916658 0.043839637269914244 TSS(ph)PLFNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSSPLFNK 8 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 T(0.033)S(0.064)S(0.903)PLFNK;TS(0.001)S(0.999)PLFNK;T(0.004)S(0.012)S(0.984)PLFNK 152.06 0.00028061 83730000.0 402640.0 401273.0 486709.0 584129.0 647120.0 589011.0 579976.0 612782.0 498934.0 428911.0 True False 470798.99949750426 441108.7315191298 498313.9884141601 551402.1459017699 520321.48138978815 558122.2262653946 525036.4746173808 596697.1217961984 506229.9658596084 506669.1690423913 0.9292039623948662 0.8706050386938459 0.9835095933624252 1.0882883340699894 1.0269452202374971 1.1015515850712803 1.0362510819628197 1.1776858712835452 0.9991331558941843 1.0 18.950684517580036 -5.529743923507369 3.4762082614070495 1.0677237398911246 0.9015223145589932 0.6005980307706457 0.05257377881298555 0.13656444658310465 3.490711777463405 0.013625510222012669 0.027879466100137237 2.9529498846488796e-06 5.529743923507369 -0.16620142533213134 TSS(ph)PLFNK ddPTM_PC-9_Lapatinib_30min_R1 2 TSSPLFNK 8 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 T(0.003)S(0.005)S(0.991)PLFNK;T(0.005)S(0.287)S(0.708)PLFNK 93.598 0.007104899999999999 48496000.0 367590.0 342200.0 313970.0 313570.0 283160.0 266460.0 280640.0 276660.0 293230.0 211864.0 True False 362348.0991922496 341407.6569247051 288156.59855924855 336630.9838388563 266505.08551397943 255064.12694859825 295170.16601793363 289514.63359698525 260203.34955120977 248484.41010896457 1.458232727893689 1.3739600676557218 1.1596566498191458 1.3547368371771813 1.072522358232102 1.0264793949718953 1.1878820320699257 1.1651219224177012 1.047161668762665 1.0 17.92279581449791 -1.5228787455970951 0.31669596791618937 1.0554588719128362 5.0579903008060505 0.7049176329004405 0.08260098530601451 32.53334966310917 0.46448661036209854 0.08073944591137633 75.15058121183621 0.02999999997811916 1.5228787455970951 4.002531428893215 TSS(ph)PSVEDATPALGVR ddPTM_PC-9_AZD4547_30min_R2 1 TSSPSVEDATPALGVR 16 0 K7ER94;Q2V2M9-2;Q2V2M9;Q2V2M9-3;Q2V2M9-4;A0A0A0MTS9;K7EP24 K7ER94 FHOD3 FH1/FH2 domain-containing protein 3 1 T(0.038)S(0.172)S(0.789)PSVEDATPALGVR 115.68 0.0018163 0.0 7258.4 8808.7 11466.0 20424.0 17031.0 17385.0 14045.0 13571.0 14889.0 16058.0 True False 9566.420215901082 11655.94001148296 11313.953348248686 15715.562347654459 14666.539626458927 16297.91320172743 15294.977791229758 11473.91378055604 15676.002143504058 15495.814307674807 0.6173551144816571 0.7521992571703686 0.7301296416958921 1.0141811224383874 0.9464839559412406 1.051762293876699 0.9870393054242023 0.7404524572079578 1.0116281617894716 1.0 13.919590950335195 -5.701886013009451 6.140173959980886 0.9573691794018989 0.7007670475703522 0.6618617388369277 0.08666014011294805 0.13039795796659923 9.70029462094978 0.024469248306022495 0.04239873232207104 1.9866162656686467e-06 5.701886013009451 -0.2566021318315467 TSS(ph)PSVEDATPALGVR ddPTM_PC-9_Lapatinib_30min_R1 1 TSSPSVEDATPALGVR 16 0 K7ER94;Q2V2M9-2;Q2V2M9;Q2V2M9-3;Q2V2M9-4;A0A0A0MTS9;K7EP24 K7ER94 FHOD3 FH1/FH2 domain-containing protein 3 1 T(0.3)S(0.022)S(0.662)PS(0.015)VEDATPALGVR 121.95 0.00077192 0.0 12357.0 10871.0 14636.0 11966.0 18622.0 16762.0 15592.0 16277.0 16954.0 13328.0 True False 12180.786914003727 10845.828867412249 13432.684576593814 12846.019557405838 17526.690572260646 16045.128334130452 16399.277467758064 17033.288842109916 15044.461986465256 15631.727041556323 0.7792348779902304 0.6938343305623905 0.8593218484997568 0.8217914452609879 1.1212254746815011 1.026446296783146 1.0491020873228682 1.089661353273864 0.9624312109896849 1.0 13.932189560103541 -6.1486330163492955 4.586045663720821 1.045128431719855 0.7793845372487196 0.8305153512379873 0.056092735856101125 0.08847858158093282 2.9721686924383177 0.016910095694760395 0.02217227842683934 7.101776224480627e-07 6.1486330163492955 -0.26574389447113544 TSS(ph)TCS(ph)NESLSVGGTSVTPR ddPTM_PC-9_Lapatinib_30min_R1 3 TSSTCSNESLSVGGTSVTPR 20 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 2 T(0.22)S(0.284)S(0.481)T(0.029)CS(0.799)NES(0.16)LS(0.026)VGGT(0.001)SVTPR;T(0.012)S(0.003)S(0.978)T(0.007)CS(0.999)NESLSVGGTSVTPR;T(0.241)S(0.094)S(0.659)T(0.047)CS(0.948)NES(0.012)LSVGGTSVTPR 190.25 2.5113e-47 2978500.0 23729.8 24445.5 30151.0 29841.9 34350.0 33644.7 31019.8 34597.7 34781.0 31514.7 True False 23391.408700487642 24388.89794667705 27672.10116622575 32036.57287566014 32329.600534698377 32205.794610626326 32625.8534629529 36205.2354471135 30863.59751983297 36961.97390430185 0.6328506361984422 0.6598375403278592 0.7486640523547665 0.8667441018871435 0.8746719160184157 0.8713223675231812 0.8826869892669805 0.9795265680575496 0.8350094505164098 1.0 15.173754183541142 -5.454962460753432 0.8884915897837551 0.9153576662530029 0.5785566009725215 0.8408049299811632 0.04606382885519375 0.36005550190974284 0.4234349863255883 0.017488883024769773 0.0972702597610591 3.5078219331121505e-06 5.454962460753432 -0.33680106528048137 TSS(ph)TDEVLSLEEK ddPTM_PC-9_AZD4547_30min_R2 4 TSSTDEVLSLEEK 13 0 K7ENH8;A0A0A0MRB7;P15923-2;K7EMM4 K7ENH8 TCF3 Transcription factor E2-alpha 1 T(0.001)SS(0.996)T(0.004)DEVLSLEEK;TSS(0.997)T(0.003)DEVLSLEEK;T(0.002)S(0.021)S(0.972)T(0.005)DEVLSLEEK;T(0.003)S(0.021)S(0.972)T(0.004)DEVLSLEEK 302.35 3.049499999999999e-114 53181100.0 111538.0 109752.0 119722.0 130356.0 134775.0 127047.0 131949.0 130861.0 128445.0 131070.0 True False 147004.76386547645 145227.18768266353 118134.40805503471 100304.43818012362 116063.8176358404 119102.73100603172 143692.205380917 110639.43933662532 135234.34047433542 126481.27919460337 1.162264999228034 1.1482109337241744 0.9340070626046862 0.7930378220305297 0.9176363361827269 0.9416629224850023 1.136074890259712 0.874749528476828 1.0692044019120381 1.0 16.948564338314505 -5.256614155002901 22.499606656839433 0.9522242910416077 1.155238097318498 0.42709213418567715 0.09102146777389508 92.54635105697832 431516.66690696724 0.024142756722230613 0.0593902897722769 5.538419465579652e-06 5.256614155002901 0.20301380627689025 TSS(ph)TDEVLSLEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TSSTDEVLSLEEK 13 0 K7ENH8;A0A0A0MRB7;P15923-2;K7EMM4 K7ENH8 TCF3 Transcription factor E2-alpha 1 TSS(0.997)T(0.003)DEVLSLEEK;T(0.13)S(0.022)S(0.77)T(0.077)DEVLSLEEK;T(0.018)S(0.001)S(0.976)T(0.005)DEVLSLEEK;T(0.212)S(0.035)S(0.729)T(0.024)DEVLSLEEK;TSS(0.999)T(0.001)DEVLSLEEK 311.54 1.8559999999999994e-115 45892500.0 82957.0 96605.0 74260.0 95486.0 110928.0 99666.0 133195.0 118210.0 97519.0 93592.0 True False 96999.98162456421 106195.30595979688 76030.64003261815 90136.2289897887 89192.45470331066 94439.33950803439 120577.80535170788 115107.11275384811 98945.03088717733 110559.48872613566 0.8773555552960326 0.9605263843327894 0.6876898664116644 0.8152735692642632 0.8067372211194574 0.8541947922893157 1.0906147155798482 1.0411328243293279 0.8949483398233847 1.0 16.754463323658634 -7.146124415227405 6.015330067677861 1.00937645428495 0.8286003114116 0.5408327078954784 0.07827108556561597 0.18923307689403537 8.707402189359453 0.0313453935148678 0.024203498380691732 7.142916688791902e-08 7.146124415227405 -0.18077614287334998 TSS(ph)TDEVLSLEEK ddPTM_PC-9_Lapatinib_30min_R1 4 TSSTDEVLSLEEK 13 0 K7ENH8;A0A0A0MRB7;P15923-2;K7EMM4 K7ENH8 TCF3 Transcription factor E2-alpha 1 T(0.306)S(0.001)S(0.693)TDEVLSLEEK;TSS(1)TDEVLSLEEK;TS(0.002)S(0.997)T(0.001)DEVLSLEEK;T(0.002)S(0.014)S(0.979)T(0.005)DEVLSLEEK 364.99 4.667499999999997e-252 37713300.0 106996.0 112826.0 121343.0 106815.0 150496.0 164403.0 165411.0 172367.0 164889.0 142557.0 True False 105470.21741933662 112564.75832900857 111366.6469375257 114670.5314243942 141644.12116652014 157371.86693211106 173975.17221776125 180375.80007667042 146317.46446185384 167197.78750473767 0.6308110830494575 0.6732431093074062 0.6660772764972744 0.6858376126606635 0.84716504494718 0.9412317548020892 1.0405351339522453 1.0788169076194225 0.8751160326072367 1.0 17.351196231083705 -6.500096053409786 1.6591509637234014 1.0041852670514024 0.6550792132429689 0.9008358758132411 0.050758319367968346 0.10407995209716685 0.5798751537846335 0.019631038078495904 0.02189199408614467 3.1615783329215836e-07 6.500096053409786 -0.3491060538084335 TSS(ph)TNEDEDLNPEQK ddPTM_PC-9_AZD4547_30min_R2 1 TSSTNEDEDLNPEQK 15 0 Q99081;Q99081-3;B4DZP2;F5GY10;B4DGI9;Q99081-4;Q99081-2 Q99081 TCF12 Transcription factor 12 1 T(0.008)S(0.008)S(0.492)T(0.492)NEDEDLNPEQK 161.94 0.00031127 23369000.0 23062.0 25268.0 25590.0 24572.0 29735.0 31362.0 34713.0 33483.0 29499.0 31182.0 True False 30395.23628060053 33435.386857328725 25250.65987979103 18907.30503361562 25606.80851346113 29400.929182201675 37802.38975200843 28308.971712796254 31058.25691659793 30090.327671062132 1.0101331103094509 1.1111672568950965 0.8391620109898168 0.6283515832829821 0.8509979948834919 0.9770890335128037 1.2562970455241331 0.9407997155185848 1.0321674544762984 1.0 14.877012196650824 -6.997178624363782 12.152894928082851 1.061564439379889 0.8862721198381969 0.24844068404731545 0.13894797520206353 0.2699937313539308 1037.1522045334245 0.054973461277358145 0.04728415562064776 1.0065176052319486e-07 6.997178624363782 -0.17529231954169222 TSS(ph)TNEDEDLNPEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSSTNEDEDLNPEQK 15 0 Q99081;Q99081-3;B4DZP2;F5GY10;B4DGI9;Q99081-4;Q99081-2 Q99081 TCF12 Transcription factor 12 1 T(0.001)SS(0.659)T(0.34)NEDEDLNPEQK;T(0.124)S(0.077)S(0.676)T(0.124)NEDEDLNPEQK 249.89 1.4737e-40 20854800.0 55953.0 64242.0 52726.0 62244.0 69304.0 61449.0 77585.0 72624.0 61003.0 60796.0 True False 65424.73777787577 70619.5211994129 53983.187804468515 58756.67047777071 55724.37870292668 58226.50626521789 70235.58713324282 70717.69695148864 61895.0534686624 71817.83353912889 0.9109817792293897 0.9833145573924463 0.7516682854970357 0.8181348222619109 0.7759128333015793 0.8107527531235544 0.9779686140904821 0.9846815681645305 0.8618340378499415 1.0 16.13205451278737 -7.263313131570454 24.99405028206172 0.9548445223800329 0.8400602530304836 0.38095831920966394 0.07136826174580654 199.06374246647667 2655287.227068896 0.030913382430914457 0.022061572302010522 5.4536450490156953e-08 7.263313131570454 -0.11478426934954933 TSS(ph)TNEDEDLNPEQK ddPTM_PC-9_Lapatinib_30min_R1 2 TSSTNEDEDLNPEQK 15 0 Q99081;Q99081-3;B4DZP2;F5GY10;B4DGI9;Q99081-4;Q99081-2 Q99081 TCF12 Transcription factor 12 1 T(0.003)S(0.001)S(0.872)T(0.124)NEDEDLNPEQK;TS(0.002)S(0.921)T(0.077)NEDEDLNPEQK 291.68 4.278999999999999e-90 30785000.0 47043.0 71961.0 79456.0 81570.0 96711.0 100137.0 106665.0 111444.0 92405.0 102669.0 True False 46372.158193370386 71794.37872577057 72923.43438902972 87568.92990954313 91022.64912114172 95854.37394074819 112187.59178414672 116622.09508632394 81997.37583221191 120415.19985215682 0.3851021984791382 0.5962235566101136 0.6055999116271329 0.7272248853720991 0.7559066399665272 0.7960321791471187 0.931673010731936 0.9684997843254841 0.6809553605598506 1.0 16.87765798752489 -4.6495303866374575 0.39296843586892966 0.9217695932326603 5.302062290342397e-20 0.7736370739268406 0.08617425372996623 3.0147192156589835 0.3404602165512725 0.07118902151855752 1.3443574270792018 2.2411432323936747e-05 4.6495303866374575 -0.9217695932326603 down TSS(ph)TSSSVNSQTLNR ddPTM_PC-9_AZD4547_30min_R2 2 TSSTSSSVNSQTLNR 15 0 A0A1B0GV57;Q9NYJ8;Q9NYJ8-2 A0A1B0GV57 TAB2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 1 T(0.049)S(0.031)S(0.917)T(0.002)SSSVNSQTLNR;T(0.001)S(0.008)S(0.94)T(0.035)S(0.011)S(0.004)SVNSQTLNR 172.09 0.00010815 9551900.0 35569.0 45099.0 59623.0 82580.0 55051.0 50394.0 45534.0 50070.0 45773.0 40613.0 True False 46879.20211883964 59676.36979098735 58832.36006302384 63542.4568482817 47408.1188994299 47242.85521356644 49586.437788953735 42332.83199413755 48192.46733256842 39191.15123163513 1.1961680288942038 1.5227000972305333 1.5011643754811244 1.6213470350161638 1.2096638503735004 1.2054469881311365 1.2652457565198423 1.0801630129192648 1.2296772566779672 1.0 15.258240331968437 -6.3831293625711005 6.328054092426536 1.1724350175602753 1.4668178591072905 0.5783092012364544 0.12369794777111406 0.17703397038073074 8.45275192661388 0.03819760604929629 0.043312439452434535 4.138763757932281e-07 6.3831293625711005 0.2943828415470151 TSS(ph)VPEYVYNLHLVENDFVGGR ddPTM_PC-9_AZD4547_30min_R2 4 TSSVPEYVYNLHLVENDFVGGR 22 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 T(0.041)S(0.041)S(0.918)VPEYVYNLHLVENDFVGGR;T(0.052)S(0.052)S(0.892)VPEY(0.003)VYNLHLVENDFVGGR;T(0.04)S(0.04)S(0.92)VPEYVYNLHLVENDFVGGR;T(0.137)S(0.137)S(0.726)VPEY(0.001)VYNLHLVENDFVGGR 150.73 9.1305e-17 55803500.0 19214.299999999996 14908.220000000001 23278.3 35149.6 34591.5 29677.3 26187.2 31321.9 27726.3 32697.1 True False 25324.047717732305 19727.010568868336 22969.61453222897 27046.402775906536 29789.06731775316 27821.573739524054 28517.810068671526 26481.820060658643 29191.855613636675 31552.38448122267 0.8026032939856907 0.6252145723125362 0.7279834760475411 0.8571904539259873 0.9441146147125936 0.8817581997988494 0.903824244587376 0.8392969500108114 0.9251869896238497 1.0 14.945461416429055 -5.8117760466858615 3.3852287276899298 0.904997225326995 0.7053372040982435 0.7062813475772733 0.05651466301436795 0.12046052576788106 2.810657232791507 0.015501161003624855 0.025542285683125797 1.5424956690488311e-06 5.8117760466858615 -0.19966002122875148 TSS(ph)VPEYVYNLHLVENDFVGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 TSSVPEYVYNLHLVENDFVGGR 22 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 T(0.315)S(0.113)S(0.365)VPEY(0.204)VY(0.003)NLHLVENDFVGGR;T(0.185)S(0.185)S(0.532)VPEY(0.096)VY(0.002)NLHLVENDFVGGR;T(0.05)S(0.05)S(0.859)VPEY(0.04)VY(0.001)NLHLVENDFVGGR;T(0.144)S(0.144)S(0.711)VPEY(0.001)VYNLHLVENDFVGGR;T(0.036)S(0.036)S(0.928)VPEYVYNLHLVENDFVGGR;T(0.093)S(0.135)S(0.742)VPEY(0.03)VYNLHLVENDFVGGR 167.95 4.7111e-09 109004400.0 24587.969999999998 20042.8 34424.9 36360.9 52185.3 38536.2 39120.799999999996 43161.399999999994 33851.3 26926.8 True False 28750.227686456088 22032.51672574936 35245.720173160276 34323.71665662832 41959.96508031052 36515.29383289706 35414.99461393516 42028.458983283446 34346.311222132215 31808.415687568482 0.9038560099581567 0.692663128593362 1.1080627378412682 1.0790765875850548 1.319146652648579 1.147975875050204 1.113384425109114 1.3212999791029898 1.079786920527312 1.0 14.957120895513334 -5.3702194448779235 4.784371877946706 1.164895776487912 0.8003746292781038 0.6230483477435365 0.10797323840723332 0.12197247025462951 4.309263200020874 0.02734110740295027 0.05950575092910211 4.2636402666891726e-06 5.3702194448779235 -0.3645211472098082 TSS(ph)VPEYVYNLHLVENDFVGGR ddPTM_PC-9_Lapatinib_30min_R1 4 TSSVPEYVYNLHLVENDFVGGR 22 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 T(0.218)S(0.218)S(0.56)VPEY(0.003)VYNLHLVENDFVGGR;T(0.136)S(0.136)S(0.728)VPEYVYNLHLVENDFVGGR;T(0.059)S(0.059)S(0.827)VPEY(0.055)VYNLHLVENDFVGGR;T(0.047)S(0.047)S(0.905)VPEYVYNLHLVENDFVGGR 142.23 8.3544e-07 75223900.0 47652.7 35318.5 33520.7 34151.9 36856.0 26399.3 23273.2 18258.7 39744.6 22031.5 True False 46973.1637595651 35236.722183212165 30764.757439643898 36663.54465339865 34688.20254168395 25270.26347877402 24478.17241935782 19107.065858661455 35268.14461880779 25839.615419871538 1.8178739503778043 1.3636705349768454 1.1906043081424795 1.4188889446552344 1.3424426787330415 0.97796592821348 0.9473117932139685 0.7394485385400696 1.3648865916048192 1.0 14.657296977600907 -6.7044388044546 4.0276146649004465 0.9835796943727241 1.41867076101891 0.5129595186146524 0.20544711002432264 0.18738915026474465 6.168077431881224 0.07133623254472905 0.06923480742021065 1.9749731492225933e-07 6.7044388044546 0.4350910666461859 TSS(ph)VVTLEVAK ddPTM_PC-9_AZD4547_30min_R2 2 TSSVVTLEVAK 11 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 T(0.006)S(0.227)S(0.766)VVT(0.001)LEVAK;T(0.414)S(0.023)S(0.563)VVTLEVAK 98.902 0.0047841 131283000.0 316701.0 323888.0 412750.0 498440.0 513990.0 463470.0 359770.0 470740.0 378070.0 430260.0 True False 417405.3302099768 428578.46202495194 407276.66531394044 383532.3588212337 442631.3606132124 434489.14763328317 391788.8330331602 397997.94952906517 398054.00835479784 415196.7283609524 1.0053194105303844 1.0322298629780293 0.9809245533357704 0.9237364666510782 1.0660762245419468 1.0464657304706864 0.9436221585362723 0.9585767958726895 0.9587118133762088 1.0 18.663435550126763 -7.278426961635334 24.908462066325317 0.9617757577879631 1.0076010864118845 0.23210658747727875 0.0388545565180635 1278.9644535097573 1875306.4257596761 0.01726822849425009 0.011667992416339989 5.2671178828027705e-08 7.278426961635334 0.04582532862392141 TSS(ph)VVTLEVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSSVVTLEVAK 11 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 T(0.024)S(0.191)S(0.785)VVTLEVAK;T(0.002)S(0.014)S(0.961)VVT(0.024)LEVAK;T(0.047)S(0.006)S(0.947)VVTLEVAK 206.36 5.6442999999999995e-06 89202600.0 214621.0 212344.0 181985.0 216027.0 260472.0 205068.0 220919.0 216418.0 188447.0 173595.0 True False 250952.0963420275 233424.1089873929 186324.21258195574 203923.70755898347 209434.38141389732 194313.87307841802 199991.95300494743 210737.25681382537 191202.68086830236 205066.3993227361 1.2237601926538726 1.1382855004930723 0.9086043018130744 0.994427698698926 1.0213003305543333 0.9475656359119291 0.9752546183355838 1.0276537624389863 0.9323940026244141 1.0 17.645731596183076 -5.081476818518575 4.270682418740848 0.9786347235767188 1.2085982356306981 0.8374637544587884 0.03691966377051881 0.07313005317818712 2.3866959108019237 0.00931650116086564 0.029422446845689985 8.28940161707759e-06 5.081476818518575 0.22996351205397936 TSS(ph)VVTLEVAK ddPTM_PC-9_Lapatinib_30min_R1 4 TSSVVTLEVAK 11 0 A8MQ02;J3KN01;P55196;P55196-5;P55196-3;P55196-1;Q5TIG5;P55196-2;P55196-6 A8MQ02 MLLT4 Afadin 1 T(0.047)S(0.047)S(0.905)VVTLEVAK;T(0.109)S(0.032)S(0.859)VVTLEVAK;T(0.05)S(0.019)S(0.838)VVT(0.093)LEVAK;T(0.019)S(0.073)S(0.906)VVT(0.001)LEVAK 165.58 0.00039084 146258000.0 358522.0 320527.0 333995.0 283244.0 315571.0 327126.0 288033.0 295585.0 322541.0 227747.0 True False 353409.410535117 319784.83942462085 306535.22035798314 304074.7086342855 297009.7342164568 313135.5835479511 302945.9393837068 309318.9581860953 286213.0360726964 267112.7654961981 1.3230719613067208 1.1971904032013494 1.147587311256175 1.1383758019554984 1.111926394325337 1.1722973365434608 1.1341499865082962 1.1580088941518518 1.0715063937173386 1.0 18.02708939941013 -1.5228787452803376 0.12437019178327559 0.9870726077618454 1.8432018958739342 0.7125435615755987 0.042567247845965286 58.07196713556729 0.4949987454239923 0.2837865475045767 8.653372539355255 0.029999999999999995 1.5228787452803376 0.8561292881120889 TSSACHILINNPINACELS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 TSSACHILINNPINACELSPK 21 0 O43303-2;O43303 O43303-2 CCP110 Centriolar coiled-coil protein of 110 kDa 1 TSSACHILINNPINACELS(1)PK 95.15299999999999 0.00035814 0.0 3561.1 3566.9 11044.0 20010.0 14784.0 12851.0 8834.9 11612.0 8689.1 13829.0 True False 4693.45572451854 4719.830670468805 10897.549343978584 15397.003651418207 12731.496790415647 12047.424938475653 9621.188984530852 9817.632217214405 9148.38808685077 13344.850919220004 0.3517053695788209 0.35368178326151545 0.816610796924177 1.1537786180318117 0.9540381430622826 0.9027770344833358 0.720966389416451 0.7356869159980274 0.6855369267313992 1.0 13.703995568183817 -5.281247325864762 5.0447111742471 0.873057030163651 0.34662829790706323 0.70549664610597 0.13433992847105866 0.10010497508849561 7.68131153639599 0.039380853093721795 0.09234035836435475 5.233023368659087e-06 5.281247325864762 -0.5264287322565877 down TSSAFVGKT(ph)PEASPEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSAFVGKTPEASPEPK 17 1 A0A087WW66;Q99460-2;Q99460 A0A087WW66 PSMD1 26S proteasome non-ATPase regulatory subunit 1 1 TSS(0.001)AFVGKT(0.997)PEAS(0.002)PEPK 71.946 0.0091413 26471000.0 126070.0 110490.0 81100.0 124500.0 128600.0 122130.0 136410.0 105650.0 109390.0 100230.0 True False 147411.1610040002 121458.71699702884 83033.73157346257 117524.66863444574 103401.75316282446 115725.28780242254 123488.25727712366 102876.7994454282 110989.62180445173 118400.90557975645 1.245017175182854 1.0258259124142646 0.7012930447354554 0.9925994067273374 0.8733189383688593 0.9774020497205439 1.0429671688105484 0.8688852415586382 0.9374051765988194 1.0 16.853320589782285 -4.8536195678725935 3.9190274000185035 0.9230952062573599 1.2530614040548995 0.5265556666717793 0.09186571548723214 0.16937689378692677 4.34595647157431 0.022736698275930604 0.13501322068030994 1.400813866494101e-05 4.8536195678725935 0.32996619779753966 TSSAVST(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 1 TSSAVSTPSK 10 0 Q9P2N5;U3KPZ7 Q9P2N5 RBM27 RNA-binding protein 27 1 TSSAVS(0.289)T(0.707)PS(0.005)K 97.45200000000001 0.012567 9642100.0 48769.0 61470.0 65993.0 67558.0 63138.0 66562.0 57331.0 54665.0 63343.0 50833.0 True False 48073.54511686071 61327.66999170556 60567.310280346785 72526.4406868814 59424.34697408403 63715.29842360053 60299.31865726258 57204.93546439383 56208.64430863917 59619.41631928512 0.8063404186885731 1.028652639993523 1.0158990815338635 1.2164902839449845 0.9967280903228503 1.0687004730536167 1.0114040421720387 0.9595017696590519 0.942790919112996 1.0 15.863494630802805 -10.328978346537456 13.085674862019689 0.9999999977096049 1.0128499863566007 0.0 0.09772931057883494 0.0 0.0 0.09630855086491708 0.023358254580366136 4.6883675726631225e-11 10.328978346537456 0.012849988646995825 TSSAVSTPS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 TSSAVSTPSK 10 0 Q9P2N5;U3KPZ7 Q9P2N5 RBM27 RNA-binding protein 27 1 TSSAVS(0.181)T(0.406)PS(0.414)K 70.816 0.034789 11071000.0 35494.0 36155.0 43852.0 46264.0 49053.0 51401.0 44558.0 50592.0 42810.0 52425.0 True False 46780.35367893655 47841.39670044005 43270.49382761218 35598.5495716748 42242.83766641359 48186.88734437686 48523.57567971632 42774.16888850423 45072.84920165284 50589.6167069281 0.9247026707069342 0.9456762042217313 0.8553236146912023 0.7036730437769788 0.8350100359750018 0.952505483951963 0.9591607693100224 0.845512808217154 0.890950596893537 1.0 15.626553688133082 -6.75366932240558 24.991044766239494 0.9218164110611471 0.8498794131046098 0.21781037175122742 0.07185166949978519 336.2708780035452 1081555.2283610452 0.026539710922906915 0.02606499656886914 1.7633181492894152e-07 6.75366932240558 -0.0719369979565373 TSSAVSTPS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 TSSAVSTPSK 10 0 Q9P2N5;U3KPZ7 Q9P2N5 RBM27 RNA-binding protein 27 1 TSS(0.001)AVS(0.095)T(0.318)PS(0.585)K 80.245 0.01792 12977000.0 57520.0 64625.0 75739.0 68171.0 85431.0 66898.0 56755.0 63930.0 70205.0 62288.0 True False 56699.754252123894 64475.364783048135 69512.03178099486 73184.5227517895 80406.11654380836 64036.92848685468 59693.49619565222 66900.42118793914 62297.77360857578 73054.39780645704 0.7761306088969279 0.8825665082321624 0.9515105711384143 1.0017812061866171 1.1006334862526446 0.87656500374567 0.817110235495995 0.9157617227258292 0.8527587041867243 1.0 16.156683504085276 -1.522903184020502 0.00665588085642636 1.766008919744948 1.9347502877836794e-06 0.04507346633469156 0.09049455113541989 182205.41440115598 94.1777826925503 11319.924213061715 13780.14798365204 0.02999831187913382 1.522903184020502 -1.7660069849946602 TSSAVWNS(ph)PPLQGAR ddPTM_PC-9_AZD4547_30min_R2 2 TSSAVWNSPPLQGAR 15 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 TSSAVWNS(1)PPLQGAR;T(0.003)SSAVWNS(0.997)PPLQGAR 169.64 5.6964e-05 19052200.0 77616.0 71543.0 77717.0 111623.0 84313.0 72809.0 60584.0 91415.0 68114.0 74350.0 True False 102296.27348690903 94667.87565038263 76686.42180061426 85890.0419081586 72607.59529831674 68256.24172013636 65975.85863324052 77288.91225772075 71714.36698251292 71747.02913037868 1.4257910707496513 1.3194675347233151 1.0688445602571184 1.1971233227243352 1.0119944502004987 0.9513458960941942 0.9195622373903345 1.0772419875012713 0.9995447595773421 1.0 16.130631474088908 -4.748300809643645 0.6896227528908794 0.988704297052377 1.7431804177369619 0.838569288618478 0.06322647010346069 1.250335979960087 0.43609165002488554 0.028753116402837273 0.7500303817719136 1.7852506108878955e-05 4.748300809643645 0.7544761206845849 TSSAVWNS(ph)PPLQGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSSAVWNSPPLQGAR 15 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 T(0.002)SS(0.003)AVWNS(0.994)PPLQGAR;T(0.012)S(0.009)S(0.009)AVWNS(0.97)PPLQGAR;TSSAVWNS(1)PPLQGAR 117.0 0.00013555 11886400.0 60924.0 57583.0 61407.0 61668.0 79433.0 66337.0 66217.0 59272.0 62568.0 42071.0 True False 71237.22989615034 63299.45968721062 62871.17576734435 58212.941890353555 63868.67386456168 62858.17094038574 59944.44639043536 57716.17280387518 63482.93863297331 49698.139266147235 1.4333983313672034 1.2736786652760692 1.2650609599416163 1.1713304109557745 1.2851320956409922 1.2647992836062314 1.2061708401076412 1.1613346828698992 1.2773705327880522 1.0 15.600904216814769 -14.522878745280323 0.07609099010160396 0.1998765013952548 1.5149231096088338 0.6512498641207289 0.0626320312651074 180.5624722824465 0.9757567977573942 24.95656957399712 2.592506485434868 3.0000000000000992e-15 14.522878745280323 1.315046608213579 TSSAVWNS(ph)PPLQGAR ddPTM_PC-9_Lapatinib_30min_R1 3 TSSAVWNSPPLQGAR 15 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 TSSAVWNS(1)PPLQGAR;T(0.006)S(0.001)S(0.007)AVWNS(0.986)PPLQGAR;T(0.001)S(0.003)S(0.02)AVWNS(0.977)PPLQGAR 160.63 0.00028736 23811400.0 92520.0 85443.0 81278.0 63463.0 83730.0 75684.0 70934.0 65800.0 79280.0 63015.0 True False 91200.64783390985 85245.16198310214 74595.63658215287 68130.28072636186 78805.16601951362 72447.1717480211 74606.61543727244 68857.3082147099 70350.65154458916 73907.05878779045 1.2339910331944686 1.1534102882901458 1.0093168068876823 0.9218372621481872 1.0662738757577557 0.9802469877206028 1.0094653563672535 0.9316743129018311 0.9518800057594929 1.0 16.17342454083303 -5.162241921157347 2.5197030005656735 0.9807064331417736 1.2279844589536537 0.8259917993768598 0.03950264427433193 0.1205095229819186 1.408038410908977 0.010881709560288652 0.04358248141194139 6.882687935035794e-06 5.162241921157347 0.24727802581188008 TSSES(ph)IYSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSESIYSR 9 0 A0A3B3IS55;F8W8M4;A0A0A0MRL6;O14639-2;O14639-6;O14639;O14639-3;O14639-5;A0A494C1P1;A0A494C1G0;H0Y7N6;F6XFR5 A0A3B3IS55 ABLIM1 Actin-binding LIM protein 1 1 TSS(0.001)ES(0.995)IYS(0.004)R 64.374 0.030604000000000003 5107900.0 7635.0 8356.3 10932.0 12577.0 12571.0 11711.0 13864.0 11927.0 12033.0 9196.3 True False 8927.454701876246 9185.858239137222 11192.660339840875 11872.351465184158 10107.802791678576 11096.854543962752 12550.701553332181 11613.928887701091 12208.959860800538 10863.516392129255 0.8217831482579887 0.8455695106045482 1.0302981038395715 1.0928645050681578 0.9304356367521843 1.0214790628937196 1.1553074621791257 1.069076390045816 1.1238497204870121 1.0 13.407203541655791 -5.269562860192707 3.7587670962977375 1.0569217677114549 0.8258572841982326 0.682469213307358 0.0601285289784269 0.12668959509294647 4.03709888765512 0.016884944324051732 0.0443829354460668 5.375726187233379e-06 5.269562860192707 -0.23106448351322229 TSSFT(ph)EQLDEGTPNR ddPTM_PC-9_AZD4547_30min_R2 2 TSSFTEQLDEGTPNR 15 0 Q13439-3;Q13439-4;Q13439;Q86W71;C9J0Y3;Q13439-5;E7EVX2;C9JHJ5 Q13439-3;Q13439-5 GOLGA4 Golgin subfamily A member 4 1 TSS(0.022)FT(0.978)EQLDEGTPNR;T(0.21)S(0.033)S(0.018)FT(0.739)EQLDEGTPNR 268.5 2.0345999999999996e-61 46449000.0 27806.0 31517.0 38197.0 40288.0 46124.0 41953.0 41336.0 54923.0 43120.0 40289.0 True False 36647.729599270584 41704.25390147336 37690.48282252358 31000.224043395156 39720.4787581934 39329.672277944825 45014.823921557385 46435.91235498337 45399.23516877527 38878.494373017216 0.9426221408590646 1.0726818148188708 0.9694429640434289 0.7973617431263026 1.0216568156446033 1.0116048193790328 1.1578335181827144 1.1943855620913966 1.1677210216320422 1.0 15.246684729083652 -7.070502582397749 2.3969215812214273 1.1468197935066022 0.9581392802362017 0.4797614041570222 0.08247772360913964 0.2533336918363346 2.873203084989752 0.03658179095181847 0.02766792221686839 8.501536379968696e-08 7.070502582397749 -0.18868051327040058 TSSFT(ph)EQLDEGTPNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSFTEQLDEGTPNR 15 0 Q13439-3;Q13439-4;Q13439;Q86W71;C9J0Y3;Q13439-5;E7EVX2;C9JHJ5 Q13439-3;Q13439-5 GOLGA4 Golgin subfamily A member 4 1 T(0.001)SS(0.061)FT(0.938)EQLDEGTPNR 221.78 3.7491e-18 66153000.0 29624.0 37075.0 33894.0 40931.0 48165.0 39021.0 61722.0 45057.0 39192.0 33121.0 True False 34638.75809932967 40755.560979861 34702.16150371081 38637.768770092436 38727.414005345505 36974.670067455445 55875.245331417274 43874.30149183767 39765.108856020495 39125.57511430827 0.8853226565521395 1.0416603682064893 0.8869431670288775 0.98753228948608 0.9898235078257762 0.9450255992258569 1.4281002941981966 1.1213714140598738 1.016345670059642 1.0 15.255824338200773 TSSFT(ph)EQLDEGTPNR ddPTM_PC-9_Lapatinib_30min_R1 2 TSSFTEQLDEGTPNR 15 0 Q13439-3;Q13439-4;Q13439;Q86W71;C9J0Y3;Q13439-5;E7EVX2;C9JHJ5 Q13439-3;Q13439-5 GOLGA4 Golgin subfamily A member 4 1 T(0.003)SS(0.145)FT(0.852)EQLDEGTPNR;TS(0.001)S(0.088)FT(0.91)EQLDEGTPNR 264.85 3.913099999999999e-61 49990000.0 28910.0 44781.0 46762.0 46035.0 74247.0 67588.0 70465.0 82121.0 77904.0 71812.0 True False 28497.738098555303 44677.31234583643 42917.408866540005 49420.567468258174 69879.93743521832 64697.41879532325 74113.33291210706 85936.64145744954 69129.6311545115 84224.60851652485 0.33835405827934545 0.5304543782720076 0.5095590187055559 0.5867711152205815 0.8296855119428415 0.7681533928724599 0.8799486779159803 1.0203269919692033 0.8207771145762973 1.0 16.361954197137138 -5.9676921760846255 0.5363521837699178 0.9704861385448408 0.295357646658977 0.8934490871163563 0.07013092896379942 0.4193465111724992 0.2116533589445443 0.050267579556771545 0.15486132868437374 1.077228472688964e-06 5.9676921760846255 -0.6751284918858638 down TSSFT(ph)EQLDEGTPNRESGDTQSFAQK ddPTM_PC-9_AZD4547_30min_R2 2 TSSFTEQLDEGTPNRESGDTQSFAQK 26 1 Q13439-3;Q13439-4;Q13439;Q86W71 Q13439-3 GOLGA4 Golgin subfamily A member 4 1 T(0.074)S(0.074)S(0.062)FT(0.79)EQLDEGT(0.001)PNRESGDTQSFAQK;T(0.195)S(0.043)S(0.195)FT(0.566)EQLDEGTPNRESGDTQSFAQK 95.13799999999999 3.3542e-09 25115000.0 35209.0 20083.4 51601.0 113593.0 84737.0 52445.0 39289.0 49537.0 36102.0 51163.0 True False 46404.72960730481 26574.966297707586 50916.73702450552 87405.88884435536 72972.73021708934 49165.60585933826 42785.6448871218 41882.19489701602 38010.27801630624 49371.7989428052 0.9399035603515765 0.5382620618805763 1.0312919139019028 1.7703606252146247 1.4780245358615482 0.995823666791931 0.8666008896432327 0.8483019819783048 0.7698783279162924 1.0 15.591399592555963 -6.996110237541762 24.86159635035545 0.8689335391739549 1.1543645476208084 0.155605561729657 0.30860185858222944 235.43367685391627 1504769.0226908084 0.12640821931431867 0.11098778110628918 1.0089967385945469e-07 6.996110237541762 0.28543100844685354 TSSGDPPS(ph)PLVK ddPTM_PC-9_AZD4547_30min_R2 2 TSSGDPPSPLVK 12 0 Q99618;F5GX58;F8WDL1 Q99618 CDCA3 Cell division cycle-associated protein 3 1 TSSGDPPS(1)PLVK;TSSGDPPS(1)PLVK 155.14 5.9204e-05 71186000.0 259800.0 284810.0 307290.0 367010.0 365190.0 314110.0 331620.0 365660.0 307800.0 315360.0 True False 342410.9958242996 376869.2627368923 303215.133820281 282401.51474797586 314489.67213825055 294468.6520445561 361133.53756693593 309155.649030883 324069.6796138462 304319.34238811367 1.1251700044343738 1.2384006214637915 0.9963715465498595 0.9279775400796414 1.033419925497756 0.9676304165674935 1.1866926851674262 1.015892209166913 1.0649000391192482 1.0 18.215226508192615 -5.267641215450567 24.992295578522455 1.025366635147425 1.1817853158683 0.45074366117846365 0.06961069352104707 410.2929544239104 1653412.4484485118 0.018614395489481624 0.040369572249392666 5.399565136376072e-06 5.267641215450567 0.15641868072087495 TSSGDPPS(ph)PLVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 TSSGDPPSPLVK 12 0 Q99618;F5GX58;F8WDL1 Q99618 CDCA3 Cell division cycle-associated protein 3 1 T(0.001)S(0.001)S(0.003)GDPPS(0.995)PLVK;T(0.004)S(0.003)S(0.067)GDPPS(0.925)PLVK;TSSGDPPS(1)PLVK;TS(0.001)S(0.008)GDPPS(0.992)PLVK;TSSGDPPS(1)PLVK;T(0.001)SS(0.003)GDPPS(0.996)PLVK 137.62 6.697e-05 89824900.0 469814.0 451118.0 418454.0 517132.0 740706.0 691547.0 732378.0 777207.0 651536.0 541942.0 True False 549344.2309505288 495902.01370500185 428431.530355633 488158.7706045637 595569.9765025123 655281.0579210836 663001.8538824518 756806.1397688856 661063.4814149876 640191.7945894874 0.8580932083060934 0.7746147606015334 0.6692237138564979 0.7625195679328999 0.9302992970792635 1.0235699105473104 1.0356300400688374 1.1821553262084143 1.0326022404565243 1.0 19.28814466025358 -6.538626530667483 1.9736239377464573 1.0719604707733774 0.7577656944947908 0.8224306986481816 0.06309512404157905 0.13164470607193005 1.0355449823065364 0.02448644018697269 0.026237917769605056 2.8931667769820774e-07 6.538626530667483 -0.3141947762785866 TSSGDPPS(ph)PLVK ddPTM_PC-9_Lapatinib_30min_R1 1 TSSGDPPSPLVK 12 0 Q99618;F5GX58;F8WDL1 Q99618 CDCA3 Cell division cycle-associated protein 3 1 TSSGDPPS(0.999)PLVK 100.22 0.0031005 25933000.0 552560.0 647450.0 462740.0 505840.0 664200.0 633480.0 601900.0 572770.0 735180.0 574530.0 True False 544680.3930729062 645950.8693042102 424695.30342805455 543041.1610327741 625133.0618674429 606387.5371140055 633063.4368806815 599382.9851996852 652376.2866113915 673836.7449868976 0.8083269384240797 0.9586162733182062 0.6302643876096614 0.8058942541688392 0.9277218354715849 0.8999027459177763 0.9394908211676571 0.8895077177949682 0.9681518431056718 1.0 19.362039576634913 -6.257548559060886 6.522813609281563 0.9304091580651049 0.7994675739576764 0.4143085731703221 0.07937548841576587 0.1582772633431358 37.52811596321521 0.024268374459736355 0.02965376245817547 5.526516117560489e-07 6.257548559060886 -0.1309415841074285 TSSIAT(ph)ALNTSGAGGSRPAQAVR ddPTM_PC-9_AZD4547_30min_R2 1 TSSIATALNTSGAGGSRPAQAVR 23 1 Q8N4C8;Q8N4C8-4;Q8N4C8-3;Q8N4C8-2;Q8N4C8-5 Q8N4C8;Q8N4C8-3 MINK1 Misshapen-like kinase 1 1 T(0.065)S(0.065)S(0.275)IAT(0.573)ALNT(0.017)S(0.007)GAGGSRPAQAVR 69.456 0.011892 10774000.0 9971.7 12802.0 14784.0 23579.0 22912.0 21339.0 20162.0 23913.0 23108.0 19350.0 True False 13142.493175755102 16939.996143245302 14587.954500306007 18143.225841918542 19731.064289908227 20004.668956667352 21956.37894103056 20217.795316073727 24329.44170408301 18672.56238968162 0.7038398320209972 0.9072132570624732 0.7812508104601246 0.9716516385530681 1.056687554612833 1.0713403195118978 1.1758631987843062 1.0827541980658206 1.302951421253644 1.0 14.1886322981809 -6.071572078419604 0.9512872716136627 1.1485941133613085 0.7692987693831352 0.7286887104097446 0.08755464541771725 0.2960503650734622 0.5516566273015265 0.03680674525957479 0.07387775564528251 8.480626206219603e-07 6.071572078419604 -0.3792953439781732 TSSIQSRPLPS(ph)PPK ddPTM_PC-9_AZD4547_30min_R2 1 TSSIQSRPLPSPPK 14 1 P56945-6;A0A2R8Y6M6;A0A2R8Y5C9;A0A2R8Y8C4;A0A2R8YFS8;A0A2R8Y5E4;A0A2R8Y4C2;A0A2R8YFK2;A0A2R8Y596;P56945;P56945-8;P56945-2;P56945-3;P56945-5;P56945-7;P56945-4 P56945-6 BCAR1 Breast cancer anti-estrogen resistance protein 1 1 TSSIQSRPLPS(1)PPK 67.01899999999999 0.016648 30179000.0 110200.0 68485.0 100140.0 112790.0 132220.0 93940.0 110100.0 95065.0 87673.0 126880.0 True False 145241.30769760557 90621.43695283191 98812.0781696863 86788.00808812887 113863.53528333061 88065.9169496849 119898.68670803808 80374.88862637672 92307.21579202314 122437.9698192662 1.1862440051235736 0.7401416169069163 0.8070378683634277 0.7088324660743629 0.929969154596466 0.7192696602179964 0.9792606565187545 0.6564539476195181 0.7539100487232855 1.0 16.901691502853105 -4.755724406151088 24.999384772071817 0.802670304589734 1.186244619980197 0.4935693215647532 0.11391887518219815 146.01769203500535 638669.5740434855 0.026303121403949588 0.22731188419314602 1.7549938295378048e-05 4.755724406151088 0.38357431539046305 TSSIQSRPLPS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSIQSRPLPSPPK 14 1 P56945-6;A0A2R8Y6M6;A0A2R8Y5C9;A0A2R8Y8C4;A0A2R8YFS8;A0A2R8Y5E4;A0A2R8Y4C2;A0A2R8YFK2;A0A2R8Y596;P56945;P56945-8;P56945-2;P56945-3;P56945-5;P56945-7;P56945-4 P56945-6 BCAR1 Breast cancer anti-estrogen resistance protein 1 1 TSSIQSRPLPS(1)PPK 65.043 0.018799 7403500.0 62676.0 26645.0 35578.0 93661.0 69933.0 73416.0 65229.0 68732.0 82434.0 60135.0 True False 73285.8088925731 29290.139509329627 36426.31445031639 88413.47782305878 56230.130668240934 69565.93571851835 59050.036902935986 66927.85782757362 83639.4413001938 71036.9994716019 1.0316568751171733 0.4123223070681469 0.5127794631145471 1.2446116598492225 0.7915611735644855 0.9792915837658426 0.8312574762753334 0.9421549097710558 1.1774067306098692 1.0 16.116283024598086 -5.745158691938945 24.99998649586853 0.9767965267174782 0.6282597758527418 0.3826087476966614 0.1979651571000742 244.83541461078048 375956.70240912435 0.052293396784188144 0.09022894812500136 1.7982137247274777e-06 5.745158691938945 -0.34853675086473634 TSSIS(ph)GPLSPAYTGQVPYNYNQLEGR ddPTM_PC-9_AZD4547_30min_R2 1 TSSISGPLSPAYTGQVPYNYNQLEGR 26 0 Q01082-3 Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 T(0.079)S(0.079)S(0.357)IS(0.486)GPLSPAYTGQVPYNYNQLEGR 209.79 2.1306999999999996e-38 26324000.0 32013.0 40700.0 49029.0 68881.0 62763.0 56291.0 52288.0 62704.0 49302.0 69277.0 True False 42192.46808823455 53855.479068120854 48378.84342502049 53001.54965084149 54049.440818239804 52771.114871351085 56941.53070472205 53014.537594575624 51908.003067972124 66851.63331627774 0.6311359348337878 0.8055970571927306 0.723674815784055 0.7928235560093055 0.8084984335764803 0.7893765979013383 0.8517597533530616 0.7930178361351582 0.7764657420170019 1.0 16.028675188162893 -14.522878745280336 0.10140316329060925 1.668685986507664 0.6390133047466118 0.685908720412393 0.04943745406049831 109.28460958644267 0.7488360584759011 15.590501907766619 0.7856706390096412 3.0000000000000132e-15 14.522878745280336 -1.0296726817610522 TSSIS(ph)GPLSPAYTGQVPYNYNQLEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSSISGPLSPAYTGQVPYNYNQLEGR 26 0 Q01082-3 Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 T(0.23)S(0.23)S(0.23)IS(0.263)GPLS(0.043)PAY(0.001)T(0.002)GQVPYNYNQLEGR;T(0.232)S(0.232)S(0.232)IS(0.305)GPLSPAYTGQVPYNYNQLEGR 168.45 1.6376e-13 45985000.0 29962.8 26352.3 31876.8 31653.0 35358.2 23917.8 23854.7 31896.5 21068.5 18343.3 True False 35034.91024772467 28968.382187716525 32636.86380543722 29879.585030410573 28430.01453096246 22663.50846311949 21595.010122927943 31059.2506721353 21376.586954813945 21668.795084517096 1.6168370281353577 1.3368709277432398 1.5061688330218734 1.3789223126559673 1.3120256304087912 1.0459053387473836 0.9965948747357035 1.4333630712271548 0.986514795651377 1.0 14.403331312680082 -6.446888809288967 2.220815283816871 1.1146986977140687 1.462016136158376 0.59710501906965 0.14169644449599184 0.2357523672309134 2.3021437301918635 0.04922089551102581 0.05571581993282902 3.5736432102442274e-07 6.446888809288967 0.3473174384443072 TSSISGPLS(ph)PAYTGQVPYNYNQLEGR ddPTM_PC-9_AZD4547_30min_R2 2 TSSISGPLSPAYTGQVPYNYNQLEGR 26 0 Q01082-3 Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 TSS(0.001)IS(0.009)GPLS(0.989)PAY(0.001)TGQVPYNYNQLEGR;T(0.001)S(0.001)S(0.001)IS(0.005)GPLS(0.923)PAY(0.064)T(0.006)GQVPYNYNQLEGR 106.66 4.5608999999999997e-10 78267000.0 38226.0 40746.8 58641.0 72943.0 62725.0 57724.0 43396.2 64062.0 44566.0 45310.0 True False 50381.07284980641 53917.40625289701 57863.38202465129 56127.11830811583 54016.716462312055 54114.50915481821 47258.37773042109 54162.689898311175 46921.6677767078 43723.71069129064 1.1522597705743638 1.233138848474653 1.3233868102639592 1.2836769208450516 1.2354101609466484 1.2376467664625117 1.0808409666802257 1.23874870275134 1.0731401117347106 1.0 15.416128222662516 -8.266232013523688 0.613920634300415 0.999553496082053 1.2534511430033783 0.6106018499474679 0.06179321019227301 0.5220174349547726 0.46349924864680836 0.06340540406170665 0.0293357668982359 5.4171141411890274e-09 8.266232013523688 0.2538976469213253 TSSISGPLS(ph)PAYTGQVPYNYNQLEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSSISGPLSPAYTGQVPYNYNQLEGR 26 0 Q01082-3 Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 T(0.005)S(0.001)S(0.001)IS(0.018)GPLS(0.932)PAY(0.038)T(0.004)GQVPYNYNQLEGR;T(0.003)S(0.003)S(0.003)IS(0.009)GPLS(0.535)PAY(0.327)T(0.118)GQVPY(0.003)NYNQLEGR;TSSIS(0.001)GPLS(0.992)PAY(0.005)T(0.001)GQVPYNYNQLEGR 125.71 5.7982e-11 32527700.0 32261.6 30639.6 35059.7 43171.6 70505.8 93761.9 117160.0 108177.8 116384.1 85391.4 True False 37722.85168435506 33681.296997937934 35895.65621265268 40752.83521621564 56690.69462012015 88844.86090560845 106061.7566350546 105338.24737385377 118085.997285415 100872.1848620497 0.37396683472201875 0.3339007382857786 0.35585286728688076 0.4040046844623045 0.5620052217333147 0.8807666952699644 1.0514470047427051 1.0442744698938735 1.1706497430080103 1.0 16.62216888581117 -6.750814285158309 1.5110036286812032 1.0833114896674165 0.35170036717485553 0.9834590022799629 0.041645583926221766 0.041748549535553854 0.19832360412466812 0.01775053268944726 0.01623822621394741 1.7749483295332236e-07 6.750814285158309 -0.731611122492561 down TSSISGPLS(ph)PAYTGQVPYNYNQLEGR ddPTM_PC-9_Lapatinib_30min_R1 2 TSSISGPLSPAYTGQVPYNYNQLEGR 26 0 Q01082-3 Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 TSSIS(0.001)GPLS(0.998)PAY(0.001)TGQVPYNYNQLEGR;TSSIS(0.002)GPLS(0.995)PAY(0.002)T(0.001)GQVPYNYNQLEGR 123.51 9.7409e-13 44216000.0 54405.0 44636.0 67350.0 45414.0 117682.0 160715.0 152526.0 162954.0 184901.0 135857.0 True False 53629.174723344884 44532.64808442765 61812.74297851833 48753.89705666288 110760.17613171402 153841.59409496348 160423.04996455045 170525.43773282436 164075.50228615152 159339.70143192643 0.33657132680304724 0.27948243710907805 0.3879305811610683 0.30597457268044187 0.6951197669906097 0.9654944292756074 1.0067989868368548 1.07020056018918 1.0297214116235076 1.0 17.281746251172756 -6.5251907137465945 1.9992084937433499 1.0308716317286326 0.3192328340637409 0.9865965572194899 0.037717256768365987 0.03247985666659968 0.26147530138552333 0.013684668539851416 0.014790720887170842 2.9840719218336814e-07 6.5251907137465945 -0.7116387976648917 down TSSLAPVVGTTTTTPS(ph)PSAIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSLAPVVGTTTTTPSPSAIK 21 0 Q92733 Q92733 PRCC Proline-rich protein PRCC 1 TSSLAPVVGTTTTTPS(0.808)PS(0.192)AIK 123.28 1.1604000000000001e-06 4294200.0 37204.0 41522.0 38569.0 43248.0 57564.0 48870.0 52568.0 49005.0 47347.0 40295.0 True False 43501.90238750541 45644.02975066186 39488.63123374702 40824.95477190777 46284.74742663156 46307.17116928181 47588.37848063807 47718.67067508948 48039.36030327625 47600.16452495553 0.9139023535243979 0.9589048736739529 0.8295902257447905 0.8576641526208235 0.9723652825268213 0.9728363679290261 0.9997523948827681 1.0024896163976875 1.0092267701740918 1.0 15.538678939614753 -6.410761741345482 4.348658771228015 0.9951643278114485 0.8910287629852522 0.7018428542869688 0.033051629276468195 0.14592468934364647 4.558335566936026 0.011580056410147444 0.013099284683408504 3.8836336790584875e-07 6.410761741345482 -0.10413556482619624 TSSLDT(ph)LAAPYLAGHWPR ddPTM_PC-9_Lapatinib_30min_R1 1 TSSLDTLAAPYLAGHWPR 18 0 Q6P1L5;Q6P1L5-2 Q6P1L5 FAM117B Protein FAM117B 1 T(0.23)S(0.23)S(0.23)LDT(0.311)LAAPYLAGHWPR 126.04 9.219399999999999e-05 5229000.0 17479.0 16440.0 16317.0 17140.0 15698.0 18861.0 18085.0 12760.0 18751.0 13236.0 True False 17229.746254743968 16401.934190070588 14975.479245441464 18400.532777363853 14774.674503455459 18054.358997138443 19021.352809415384 13352.876182670176 16639.064923216345 15523.824964138606 1.1098905259848129 1.0565652619738042 0.9646771514131427 1.1853092146987416 0.9517418894883348 1.1630096988883598 1.2253006493796712 0.860153745195948 1.0718405394066244 1.0 13.922196451050532 -7.768523401905781 24.999999547514136 0.9744979180084276 1.0881071700662752 0.23405265404578846 0.09611510798418496 256.7102081364382 905929.2991370072 0.050195237126789194 0.024920672256067793 1.7040274955255148e-08 7.768523401905781 0.11360925205784767 TSSNASTISGRLS(ph)PIMTEQDDLGEGDVHSMVYPPSAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSNASTISGRLSPIMTEQDDLGEGDVHSMVYPPSAAK 38 1 Q12778 Q12778 FOXO1 Forkhead box protein O1 1 T(0.032)S(0.032)S(0.032)NAS(0.028)T(0.024)IS(0.167)GRLS(0.515)PIMT(0.167)EQDDLGEGDVHS(0.001)MVYPPSAAK 47.534 0.0013610999999999999 10939000.0 27465.0 19145.0 20653.0 29074.0 21415.0 14635.0 12201.0 10770.0 10536.0 8936.0 True False 32114.282041523427 21045.589075102856 21145.44584693868 27445.078039179767 17218.884478863773 13867.514836554936 11045.23295240954 10487.298911758251 10690.06906784629 10556.026062662919 3.042270059858313 1.9937037811551013 2.0031634747218896 2.59994413392499 1.6311900308552332 1.313706005861892 1.0463438501233875 0.9934892969668048 1.0126982450012592 1.0 13.365779197322112 -6.592878428774216 1.7444958178830798 1.019515338276889 2.367650587106713 0.8204935911361391 0.2941253517439391 0.14948217882324863 0.9303127228258815 0.11575264826606259 0.11993868091852626 2.553415975490761e-07 6.592878428774216 1.348135248829824 up TSSPRS(ph)PPSSSEIFTPAHEENVR ddPTM_PC-9_AZD4547_30min_R2 1 TSSPRSPPSSSEIFTPAHEENVR 23 1 I3L3A7;I3L2L5;I3L317;I3L4Q0;C9JLW8 I3L3A7 FAM195B Protein FAM195B 1 T(0.049)S(0.049)S(0.049)PRS(0.838)PPS(0.014)S(0.002)S(0.001)EIFTPAHEENVR 79.237 0.00010917 14063000.0 9540.0 11465.0 39619.0 100790.0 61199.0 34469.0 13814.0 45297.0 14001.0 31846.0 True False 12573.52155567293 15170.837039705315 39093.62617340529 77554.42268997712 52702.57522163464 32313.647981037833 15043.419238736054 38297.38947150889 14741.064276391995 30731.081233168003 0.40914673519857647 0.49366427834408433 1.2721201013653762 2.523647707073605 1.7149600048810791 1.0514972687053317 0.48951805908149165 1.2462102840096165 0.47967932415218734 1.0 14.90741090672399 -6.997999019637778 24.853650225237267 0.8166748706681132 1.314825320287339 0.12413519286747221 0.596359671069497 143.4462680861402 1781675.9117054893 0.23761544275479263 0.20815985465496775 1.0046180580679282e-07 6.997999019637778 0.49815044961922583 TSSPRS(ph)PPSSSEIFTPAHEENVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSPRSPPSSSEIFTPAHEENVR 23 1 I3L3A7;I3L2L5;I3L317;I3L4Q0;C9JLW8 I3L3A7 FAM195B Protein FAM195B 1 T(0.119)S(0.119)S(0.119)PRS(0.611)PPS(0.011)S(0.011)S(0.011)EIFTPAHEENVR 93.255 5.2536e-06 17339000.0 14727.0 5965.8 11380.0 25132.0 23867.0 26237.0 16661.0 28320.0 23938.0 16469.0 True False 17219.99022849136 6558.045197401341 11651.342358890326 23723.935519043356 19190.432680693048 24861.085532401215 15082.749464805791 27576.63000752033 24288.047963753288 19454.69933146773 0.8851326836307484 0.3370931149161368 0.5988960384519758 1.2194449842085295 0.9864163076348739 1.2778961580860169 0.7752753824578329 1.4174791158512265 1.248441188935142 1.0 14.247831063465853 -5.754843048563918 24.897013594664013 1.1346636120787077 0.5800456502876385 0.5659506251572008 0.2103245704207144 98.76312567767624 372763.96576966223 0.05556530447940015 0.09342986745458925 1.7585590318815672e-06 5.754843048563918 -0.5546179617910691 TSSPRS(ph)PPSSSEIFTPAHEENVR ddPTM_PC-9_Lapatinib_30min_R1 1 TSSPRSPPSSSEIFTPAHEENVR 23 1 I3L3A7;I3L2L5;I3L317;I3L4Q0;C9JLW8 I3L3A7 FAM195B Protein FAM195B 1 T(0.068)S(0.068)S(0.02)PRS(0.842)PPSS(0.001)SEIFTPAHEENVR 119.29 9.0656e-09 15980000.0 25414.0 5223.9 21221.0 13353.0 10518.0 11805.0 6918.6 6631.3 14520.0 8369.2 True False 25051.591699643173 5211.804380505462 19476.2912954289 14335.02416430219 9899.351919183628 11300.127668799067 7276.811255030211 6939.414406750849 12884.60469762153 9815.80506874198 2.552168826112788 0.5309604606047277 1.9841766578525823 1.4604022863036954 1.0085114618573365 1.1512176117661352 0.7413361618399403 0.7069633471888234 1.3126386075709686 1.0 13.26089088358633 -6.227535590055898 3.5331743834576304 0.9615519881826854 1.5935369668127264 0.28869785340398046 0.49779898603565464 0.33000371902368675 8.691493162113145 0.1472384050637765 0.1871559973536526 5.921945550577252e-07 6.227535590055898 0.631984978630041 TSSS(ph)SPANSDVEIDGIGR ddPTM_PC-9_Lapatinib_30min_R1 2 TSSSSPANSDVEIDGIGR 18 0 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 T(0.003)S(0.002)S(0.103)S(0.879)S(0.013)PANSDVEIDGIGR;TSSS(0.499)S(0.499)PANS(0.002)DVEIDGIGR 289.81 3.608799999999999e-106 10612900.0 46698.0 42249.0 41633.0 35329.0 32866.0 39983.0 37773.0 36263.0 34244.0 26262.0 True False 46032.07795663562 42151.1750362708 38210.09544802749 37927.21251408915 30932.88649704212 38273.0202949253 39728.70111529155 37947.91136459004 30387.080114693654 30801.351708084632 1.4944823978148103 1.3684845858633894 1.2405330717352328 1.2313489639525836 1.0042704226166466 1.2425759965878227 1.2898362867907416 1.2320209750609616 0.9865502138569379 1.0 14.910706044098196 -1.5228787452911428 0.468822144953805 1.1305692860731291 10.926791093228449 0.5781070572430793 0.10304880715085635 75.44211379213738 0.8695108009436354 0.06388518646918197 715.6403245508948 0.029999999999253603 1.5228787452911428 9.79622180715532 TSSSS(ph)PANSDVEIDGIGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSSSSPANSDVEIDGIGR 18 0 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 T(0.006)S(0.007)S(0.039)S(0.22)S(0.72)PANS(0.007)DVEIDGIGR;TSSS(0.033)S(0.967)PANSDVEIDGIGR 216.53 1.5774e-27 9712200.0 26027.0 25207.0 26504.0 32280.0 35093.0 28739.0 32643.0 30481.0 29297.0 19335.6 True False 30432.857043318032 27709.38437274056 27135.955876979733 30471.456253172026 28216.778567208356 27231.876247881948 29550.81872514586 29680.90604728909 29725.413200521343 22840.991219474625 1.3323790001447244 1.2131428144464702 1.1880375775392422 1.3340689097236522 1.2353570077620029 1.1922370612648183 1.2937625360124616 1.2994578808813968 1.3014064457577892 1.0 14.479337639549282 -11.14864162260313 3.5126207645727665 0.9872773900775866 1.2625179849563675 0.6972759926544448 0.05245526858764491 39809276.71499302 44911.36260095231 4096225.8898647283 0.012904999220847688 7.101635492590589e-12 11.14864162260313 0.27524059487878083 TSSSS(ph)PLSSPSK ddPTM_PC-9_Lapatinib_30min_R1 1 TSSSSPLSSPSK 12 0 A0A087WVA8;Q8IWB9;Q8IWB9-2 A0A087WVA8 TEX2 Testis-expressed sequence 2 protein 1 TSSS(0.024)S(0.974)PLS(0.001)SPSK 187.62 0.00031211 3831500.0 54209.0 62140.0 48174.0 39852.0 40492.0 37545.0 26651.0 25449.0 43295.0 24355.0 True False 53435.9697192869 61996.11864787026 44213.31967701766 42782.84902237481 38110.34017033499 35939.287871669694 28030.85837565548 26631.45344614211 38418.66118343831 28564.729299002403 1.8706975711179976 2.1703730498869254 1.5478291152075356 1.4977509002288694 1.3341747359624359 1.2581700843538133 0.9813101353855446 0.9323194757904528 1.3449685022843905 1.0 14.801947237465804 -5.778006712069811 0.7729406504347708 1.0633135455437217 2.1323495708120173 0.8284737219044206 0.15648096965747654 0.35045881720654104 0.37117232700605696 0.07485611474736137 0.25816427976171136 1.6672214452579646e-06 5.778006712069811 1.0690360252682956 TSSSSPANS(ph)DVEIDGIGR ddPTM_PC-9_AZD4547_30min_R2 3 TSSSSPANSDVEIDGIGR 18 0 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 TSSS(0.005)S(0.08)PANS(0.914)DVEIDGIGR;T(0.206)S(0.206)S(0.039)S(0.171)S(0.143)PANS(0.235)DVEIDGIGR;TSSS(0.002)S(0.022)PANS(0.977)DVEIDGIGR 136.61 4.4229000000000005e-08 6451500.0 13154.5 13182.7 20578.800000000003 31955.0 26484.6 21373.199999999997 17505.8 25132.399999999998 18025.5 20457.5 True False 17337.35736940247 17443.749973251048 20305.911666050946 24588.26844982855 22807.670447473083 20036.7304252609 19063.782286771788 21248.76506509813 18978.291130212398 19741.289151778383 0.878228226946397 0.8836175712303792 1.0286010964092331 1.2455249634805905 1.1553283208669514 1.0149656525068376 0.9656807182247487 1.0763615740456316 0.9613501420449408 1.0 14.268928583738388 -5.304237465719414 4.509591642702555 1.0658991040549248 0.8786825177128991 0.41719523221194543 0.08290424870984797 0.19335770200097832 9.048336951294935 0.024001931534293024 0.055652211078160145 4.96320866425664e-06 5.304237465719414 -0.18721658634202576 TSSSSSGESCAGDKS(ph)PPGQASSK ddPTM_PC-9_AZD4547_30min_R2 1 TSSSSSGESCAGDKSPPGQASSK 23 1 O43365 O43365 HOXA3 Homeobox protein Hox-A3 1 T(0.002)S(0.002)S(0.004)S(0.011)S(0.011)S(0.011)GES(0.012)CAGDKS(0.935)PPGQAS(0.009)S(0.003)K 46.29600000000001 0.025047999999999997 6852800.0 15606.0 15784.0 14778.0 18763.0 16987.0 16835.0 14460.0 16675.0 15715.0 14006.0 True False 20568.38337503478 20885.869327057004 14582.034064226335 14437.480235460276 14628.648266963648 15782.304788673082 15746.911987268231 14098.261903380153 16545.66281719164 13515.654203094618 1.5218192967918143 1.5453095361284739 1.078899611155156 1.0682043220782158 1.0823485158131814 1.167705576919797 1.165086924439272 1.0431061413329248 1.2241851240469925 1.0 13.722343724401565 -5.260048822939167 24.999857777019958 1.1076807120978263 1.5335644599660043 0.881994404026683 0.06288172173757849 34.146779271904734 613884.7857644268 0.015644960704809596 0.03706510037443612 5.49479098509982e-06 5.260048822939167 0.42588374786817806 TSSSSSGESCAGDKS(ph)PPGQASSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSSSSGESCAGDKSPPGQASSK 23 1 O43365 O43365 HOXA3 Homeobox protein Hox-A3 1 T(0.002)S(0.002)S(0.015)S(0.015)S(0.015)S(0.053)GES(0.053)CAGDKS(0.817)PPGQAS(0.021)S(0.007)K 51.052 0.012915000000000001 5215700.0 19430.0 25767.0 19243.0 20787.0 22015.0 18656.0 24262.0 21218.0 17163.0 17568.0 True False 22719.115240007268 28324.977471829476 19701.826099483897 19622.371782363294 17701.31878599982 17677.646517988996 21963.727718331313 20661.049982329318 17413.97640579404 20752.939331788522 1.0947420448151668 1.3648658158240943 0.949351115256499 0.9455225338757932 0.8529547792242446 0.8518141086121273 1.0583429829955775 0.9955722248308965 0.8391089150017419 1.0 14.341028065843997 -5.287483114256425 18.620595329668348 0.9350778184200216 1.2298026432025246 0.6243651263376921 0.09096817193061553 16.656948021441053 11909.495527894613 0.02345526641385814 0.04894020198417381 5.158422210723286e-06 5.287483114256425 0.29472482478250306 TSSSSSGESCAGDKS(ph)PPGQASSK ddPTM_PC-9_Lapatinib_30min_R1 3 TSSSSSGESCAGDKSPPGQASSK 23 1 O43365 O43365 HOXA3 Homeobox protein Hox-A3 1 TSSSSSGES(0.001)CAGDKS(0.997)PPGQAS(0.001)SK;TSSSSSGESCAGDKS(0.999)PPGQAS(0.001)SK;T(0.005)S(0.001)S(0.001)S(0.001)S(0.001)S(0.003)GES(0.003)CAGDKS(0.955)PPGQAS(0.014)S(0.014)K 102.66 1.7844999999999998e-06 17649700.0 35122.6 49104.4 49926.7 48853.1 54922.1 57275.9 50351.7 61005.1 49279.1 45013.9 True False 34621.745283304 48990.70177876537 45821.91944863532 52445.919943164205 51691.69005900315 54826.34327364409 52958.66465323973 63839.61965606682 43728.7688260717 52794.49263774852 0.6557832749878375 0.9279509913073128 0.8679299138840906 0.9933975557455196 0.9791114087162028 1.0384860339474649 1.0031096428299384 1.209209833573075 0.8282827742302281 1.0 15.688099819386652 -4.06188275940201 0.7107681080725148 1.0229928502331558 1.1280530088047906e-10 0.5359967171705198 0.09430565718234799 5.42613409925749 0.991054956863068 0.035845493460180976 5.64320162035004 8.671959493046879e-05 4.06188275940201 -1.0229928501203505 TSSSTS(ph)PLEPPSDR ddPTM_PC-9_AZD4547_30min_R2 1 TSSSTSPLEPPSDR 14 0 A0A0U1RR46;A0A0X1KG69;A0A087WUZ6;A0A2R8Y549;Q8NI35-4;Q8NI35-3;Q8NI35-2;Q8NI35 A0A0U1RR46 INADL InaD-like protein 1 T(0.004)S(0.001)S(0.005)S(0.03)T(0.109)S(0.851)PLEPPSDR 106.55 0.00086527 14592000.0 42534.0 42250.0 54470.0 69504.0 55112.0 62437.0 45666.0 81032.0 60794.0 54042.0 True False 56058.927237839875 55906.48625621882 53747.692209934256 53480.92662609554 47460.650102366526 58532.80451977315 49730.185533235854 68510.36633011703 64007.44672658912 52150.00602910458 1.0749553357012798 1.0720322107924163 1.0306363565890677 1.0255210056207507 0.9100794748878657 1.1223930537439701 0.9535988453286421 1.3137173232900843 1.2273717991684792 1.0 15.670379799085646 -7.75410218436102 24.999999445262844 1.2029084296680315 1.0280119585976313 0.3559653206025768 0.09303585209743552 149.39060455454276 509022.7626408548 0.04264251073342245 0.023983309315317704 1.7615615230312887e-08 7.75410218436102 -0.17489647107040018 TSSSTS(ph)PLEPPSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSSTSPLEPPSDR 14 0 A0A0U1RR46;A0A0X1KG69;A0A087WUZ6;A0A2R8Y549;Q8NI35-4;Q8NI35-3;Q8NI35-2;Q8NI35 A0A0U1RR46 INADL InaD-like protein 1 T(0.012)SS(0.004)S(0.019)T(0.122)S(0.842)PLEPPSDR 93.649 0.0036710000000000002 11067000.0 36066.0 23440.0 33312.0 28759.0 38137.0 44770.0 34762.0 33950.0 28970.0 25937.0 True False 42171.26146402995 25766.968290436722 34106.2844164635 27147.726467936 30664.3286187452 42422.182386919354 31469.091704914375 33058.84847299839 29393.63144414455 30639.172782820962 1.3763838130667452 0.8409811998868315 1.1131594399828741 0.8860463257401461 1.0008210350880733 1.3845733593272789 1.0270868579898065 1.0789732708297566 0.9593480755010863 1.0 14.90308972647837 -8.252928000485113 21.396257445329777 0.9796740327180572 1.0792248311831238 0.05992748785554558 0.16925205685259892 267.76696209166784 673159.0897072663 0.11713503355146956 0.04225770996161666 5.585627883985805e-09 8.252928000485113 0.09955079846506665 TSST(ph)NEDEDLNPEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSTNEDEDLNPEQK 15 0 Q99081;Q99081-3;B4DZP2;F5GY10;B4DGI9;Q99081-4;Q99081-2 Q99081 TCF12 Transcription factor 12 1 T(0.097)S(0.097)S(0.107)T(0.7)NEDEDLNPEQK 104.26 0.0028604 16864000.0 12752.0 13307.0 10878.0 16586.0 20415.0 11064.0 20525.0 14258.0 14817.0 16456.0 True False 14910.661736519445 14628.03101710074 11137.372775044734 15656.74019253752 16414.82730030372 10483.784362941158 18580.72341186835 13883.742607599737 15033.67059398999 19439.34253437567 0.7670352899102473 0.7524961809399252 0.5729294987909133 0.8054151093253712 0.8444126786323389 0.5393075585968043 0.9558308558538449 0.7142084452212487 0.7733631200440608 1.0 14.246691805363731 -14.522878745243252 0.2072121912982352 2.214791647858147 0.7083190679762845 0.3198219361477206 0.1135784175519532 172.25907469526885 1.7094368774598385 86.64713195803846 0.2422885699222826 3.0000000002561753e-15 14.522878745243252 -1.5064725798818626 TSSTCS(ph)NES(ph)LSVGGTSVTPR ddPTM_PC-9_AZD4547_30min_R2 1 TSSTCSNESLSVGGTSVTPR 20 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 2 T(0.019)S(0.022)S(0.077)T(0.237)CS(0.796)NES(0.791)LS(0.058)VGGTS(0.001)VTPR 85.271 0.0123 0.0 3404.2 4841.9 5246.2 6732.4 4576.8 4484.5 5024.7 4757.4 4385.7 4629.4 True False 4486.6647882412735 6406.9494864848775 5176.631960193813 5180.34919454313 3941.390321318608 4204.0835060768895 5471.888565866297 4022.2531441763526 4617.519148415993 4467.326115079695 1.0043289145818792 1.4341799370450885 1.158776374690851 1.1596084684878025 0.8822705618052457 0.9410737872674627 1.22486884210124 0.90037150648103 1.0336203423406483 1.0 12.125195859973754 -6.072591721583402 5.176985379783092 1.0007221933279575 1.2140751121932474 0.3368835561445721 0.13219689469822687 0.23859673321627492 11.798703999400182 0.03848496859230042 0.05096362415765288 8.46073861886335e-07 6.072591721583402 0.21335291886528984 TSSTCS(ph)NES(ph)LSVGGTSVTPR ddPTM_PC-9_Lapatinib_30min_R1 1 TSSTCSNESLSVGGTSVTPR 20 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 2 T(0.09)S(0.142)S(0.219)T(0.309)CS(0.784)NES(0.419)LS(0.037)VGGTSVTPR 87.863 0.008406100000000001 0.0 6651.3 7274.0 8801.0 7382.6 9035.6 9285.5 7951.3 9722.7 9699.8 7552.4 True False 6556.4512423009655 7257.157499913232 8077.415752842454 7925.5410316316475 8504.143772673093 8888.380810557706 8362.979407990304 10174.452136461392 8607.306380577782 8857.822277059562 0.7401877162608236 0.8192936449750394 0.9118963442924064 0.8947505135836397 0.9600716188105914 1.003449892371095 0.9441349291517366 1.1486403563110208 0.971718116637926 1.0 13.112736336008481 -4.475611337513653 0.42080812536228007 1.0386239592828994 0.44471897244770514 0.7476760184646724 0.05266243850099258 3.289858123321742 0.3762051739484172 0.039052945449513564 1.0338166812124412 3.344942545421907e-05 4.475611337513653 -0.5939049868351942 TSSTCS(ph)NESLSVGGTSVTPR ddPTM_PC-9_AZD4547_30min_R2 2 TSSTCSNESLSVGGTSVTPR 20 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 T(0.001)SS(0.005)T(0.003)CS(0.987)NES(0.003)LSVGGTSVTPR;TSSTCS(0.992)NES(0.003)LS(0.006)VGGTSVTPR 190.37 1.0532999999999999e-47 0.0 12807.2 16988.4 20257.3 25729.0 22035.9 18008.800000000003 15777.900000000001 26454.0 13957.5 15650.900000000001 True False 16879.62319369122 22479.568073731338 19988.67496611531 19797.576559087414 18976.59565232144 16882.70688911528 17182.10253415763 22366.14215244489 14695.264955199007 15102.966754763213 1.1176362543715248 1.4884206817605339 1.3234932772272197 1.3108402395736987 1.2564813232033736 1.1178404324958717 1.1376640638329352 1.4809105068969974 0.97300518459821 1.0 13.882544353071557 -8.810989151027428 0.2731211134365742 0.934920208678537 1.3462116332619696 0.27763867426305266 0.14659904080996183 4.263619612484957 0.8185232858005738 0.5752083591867587 0.25876476280332567 1.5452930415311281e-09 8.810989151027428 0.4112914245834326 TSSTCS(ph)NESLSVGGTSVTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSSTCSNESLSVGGTSVTPR 20 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 T(0.001)S(0.002)S(0.014)T(0.04)CS(0.892)NES(0.045)LS(0.002)VGGT(0.002)S(0.002)VTPR;TSS(0.018)T(0.003)CS(0.978)NESLSVGGTSVTPR;T(0.003)SS(0.025)T(0.055)CS(0.912)NES(0.004)LS(0.001)VGGTSVTPR 193.71 2.4357e-15 21170200.0 50323.0 52532.0 49524.0 50219.0 50425.0 27263.8 25327.600000000002 23912.800000000003 20423.800000000003 14691.1 True False 58841.689975444504 57747.02978810674 50704.83998081589 47405.392242194735 40544.58322889124 25834.038332823133 22928.386372055415 23285.11433770594 20722.45943696652 17354.480135316382 3.390576353578095 3.3274998350766776 2.921714714901283 2.7315939096167288 2.3362603150746635 1.4886091736191418 1.321179671950883 1.341735053781341 1.1940697315845432 1.0 14.083020528499683 -6.423833966588834 0.8237469507748028 1.1142218073831371 3.412586724462885 0.9836079831783602 0.1137105454921914 0.07546108438536678 0.11266774096440686 0.06823814796214071 0.09465826811097294 3.768478426607705e-07 6.423833966588834 2.2983649170797475 up TSSTCS(ph)NESLSVGGTSVTPR ddPTM_PC-9_Lapatinib_30min_R1 2 TSSTCSNESLSVGGTSVTPR 20 0 O60343-2;A0A3B3IRT3;O60343-3;O60343;Q5JU47 O60343-2 TBC1D4 TBC1 domain family member 4 1 TSS(0.001)T(0.002)CS(0.982)NES(0.012)LS(0.002)VGGTSVTPR;TSS(0.002)T(0.009)CS(0.988)NES(0.001)LSVGGTSVTPR 128.44 9.2689e-06 20575400.0 102679.0 99751.0 104286.0 75293.0 53097.0 35555.0 22333.2 29805.5 29922.0 19112.4 True False 101214.77863097737 99520.03268818335 95712.00763560148 80830.29839008489 49973.93885271849 34034.39553275316 23489.503818813137 31190.37234032729 26551.869267371305 22415.952874327817 4.515301187436694 4.439696730544078 4.26981659767928 3.605927387662245 2.2293916806879017 1.5183113438702633 1.0478922734404397 1.3914363808307475 1.1845077216315976 1.0 14.452238207416675 -6.297562193496436 1.3625515444705727 1.1689635498122195 4.505561622901315 0.9944756665610993 0.10649650365733426 0.027631240477357516 0.10377725043626296 0.04192855161181203 0.05707529670623675 5.040084369939589e-07 6.297562193496436 3.336598073089095 up TSSVLGMSVES(ph)APAVEEEKGEELEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSSVLGMSVESAPAVEEEKGEELEQK 26 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 T(0.034)S(0.038)S(0.269)VLGMS(0.129)VES(0.529)APAVEEEKGEELEQK 78.352 7.819399999999999e-05 5086300.0 40192.0 44348.0 37968.0 55288.0 48217.0 39502.0 55706.0 34785.0 36794.0 42325.0 True False 46995.71177181539 48750.57635427852 38873.301114441834 52190.39260611447 38769.22497863061 37430.44558070333 50429.12440348544 33871.93060775404 37332.04264259078 49998.187455484374 0.9399483093993712 0.9750468734028277 0.7774942071460585 1.0438456924579897 0.7754126089700469 0.7486360503374114 1.0086190514083084 0.6774631707981762 0.7466679202286917 1.0 15.609588174509165 -6.292220149467449 24.867245034299746 0.8152557296800156 0.9258247933893755 0.16180631417827918 0.11823271642617468 1146.6786354900478 926378.269404313 0.03582758683560382 0.040628825043355556 5.102462839933767e-07 6.292220149467449 0.11056906370935993 TSSVSNPQDSVGS(ph)PCSR ddPTM_PC-9_AZD4547_30min_R2 6 TSSVSNPQDSVGSPCSR 17 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 TSSVSNPQDS(0.002)VGS(0.985)PCS(0.013)R;TSSVSNPQDSVGS(1)PCSR;TSSVSNPQDS(0.016)VGS(0.975)PCS(0.009)R;TSSVSNPQDSVGS(0.994)PCS(0.006)R;TSSVSNPQDSVGS(1)PCSR;TSSVSNPQDSVGS(0.88)PCS(0.12)R 264.01 3.4203999999999996e-69 872990400.0 141545.0 140239.0 176402.0 247052.0 201546.0 185581.0 140530.0 196024.0 157349.0 162917.0 True False 186553.36568110346 185568.51422688467 174062.79422098072 190097.97831535086 173564.81683719598 173976.59073280258 153036.8977573171 165732.99498339964 165666.14690564983 157213.32541807526 1.186625657748824 1.1803612304071862 1.1071758310442064 1.2091721729683276 1.1040083044846067 1.1066275092785487 0.9734346458886242 1.0541917775905327 1.053766571409237 1.0 17.2623639802001 -6.831409059653517 1.8435522109314584 1.0257369938774001 1.1655218455992333 0.7466579866408666 0.03772833570667258 0.17273719808825444 1.2089023896205753 0.015577074384866215 0.01354133645762287 1.4743172275645115e-07 6.831409059653517 0.1397848517218332 TSSVSNPQDSVGS(ph)PCSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TSSVSNPQDSVGSPCSR 17 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 TSSVSNPQDSVGS(0.853)PCS(0.147)R;TSSVSNPQDS(0.001)VGS(0.999)PCS(0.001)R;TSSVSNPQDS(0.009)VGS(0.991)PCS(0.001)R;TSSVSNPQDS(0.001)VGS(0.999)PCS(0.001)R;TSSVSNPQDSVGS(0.996)PCS(0.004)R 194.67 4.4089e-12 445848400.0 83545.2 91885.0 97893.5 109123.0 136265.0 143691.0 163486.0 156627.0 146143.0 107100.0 True False 97687.75226708448 101006.73555319034 100227.65230316602 103009.19209153914 109564.85143648698 136155.59100645143 147999.42254385905 152515.70721002456 148280.06489960747 126516.3821968663 0.7721352015510298 0.798368826228515 0.79221086283677 0.8141964724477443 0.8660131560353834 1.0761894123291165 1.1698044156334158 1.2055016477842522 1.172022645011108 1.0 16.948964681363776 -6.762344811185341 2.2678969715291712 1.1543848867087276 0.7947200080479875 0.9009520299345233 0.05299666613262046 0.08022105666687071 0.8473660781147722 0.019803799095288656 0.018261595918418833 1.7284435043092638e-07 6.762344811185341 -0.35966487866074015 TSSVSNPQDSVGS(ph)PCSR ddPTM_PC-9_Lapatinib_30min_R1 6 TSSVSNPQDSVGSPCSR 17 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 TSSVSNPQDS(0.023)VGS(0.971)PCS(0.006)R;TSSVSNPQDSVGS(0.856)PCS(0.144)R;TSSVSNPQDS(0.001)VGS(0.954)PCS(0.045)R;TSSVSNPQDS(0.161)VGS(0.724)PCS(0.115)R;TSSVSNPQDSVGS(1)PCSR;TSS(0.001)VS(0.001)NPQDS(0.022)VGS(0.976)PCS(0.001)R 214.46 1.4919999999999996e-66 533449200.0 129637.5 140825.5 164058.0 138245.0 185587.0 211106.0 191686.0 192674.0 219757.0 183917.0 True False 127788.8454773939 140499.42720704313 150569.78452219348 148411.9984718006 174671.13753808054 202077.48849212175 201610.5631531989 201626.33743101847 195005.65251619922 215706.8083960014 0.592419156482048 0.6513444255737623 0.6980298194657477 0.6880264910291618 0.8097618190030133 0.9368155321325856 0.9346509025485918 0.9347240308746604 0.904031050138212 1.0 17.71871218771836 -6.395741483529508 1.3485902328556554 0.9454016609016284 0.638615695695934 0.9466271791212838 0.03199498679435445 0.09090549770721604 0.33729760000873227 0.013203309618940133 0.016496397098884757 4.020300505060255e-07 6.395741483529508 -0.30678596520569434 TSSVSNPQDSVGSPCS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSSVSNPQDSVGSPCSR 17 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 TSSVSNPQDSVGS(0.439)PCS(0.561)R;TSS(0.004)VS(0.2)NPQDS(0.029)VGS(0.311)PCS(0.456)R 224.99 6.1916e-29 72986000.0 16557.9 16353.3 20861.4 20736.7 30979.0 32168.5 38791.6 32027.1 31320.2 24158.1 True False 19360.825436568004 17976.747548805404 21358.81489330006 19574.889928288492 24908.88733461224 30481.527230592248 35116.97882113679 31186.422560517454 31778.198673002997 28537.772294585633 0.6784280579686756 0.6299282005349824 0.7484401610896724 0.6859291512394037 0.8728392348739187 1.0681116562267685 1.2305438020401966 1.0928120891354347 1.1135486801481052 1.0 14.800585099612189 -6.579328838038912 2.1299370210500803 1.1217646735212845 0.6829337274692151 0.9149004964250416 0.0598138697496399 0.08061263672472979 0.7420676835375463 0.02204236169367134 0.022898118537525103 2.634335970379653e-07 6.579328838038912 -0.4388309460520694 TSSVSNPQDSVGSPCS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 TSSVSNPQDSVGSPCSR 17 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 TSSVSNPQDSVGS(0.04)PCS(0.96)R 152.13 5.0093e-12 0.0 3176.2 11597.0 3426.9 5313.1 3712.1 4076.3 5190.2 4707.0 3748.8 4609.4 True False 3130.906805556257 11570.147859017556 3145.1535102165453 5703.843097982023 3493.7615762693977 3901.966151319413 5458.923160156361 4925.704403748321 3326.5706673859254 5406.128648360569 0.5791402700906345 2.14019099647698 0.581775557851426 1.055069804843016 0.6462594221335993 0.7217671655858023 1.0097656780350208 0.9111334050923966 0.6153332419114225 1.0 12.400380128414726 TSSVSSISQVS(ph)PER ddPTM_PC-9_AZD4547_30min_R2 3 TSSVSSISQVSPER 14 0 P42356 P42356 PI4KA Phosphatidylinositol 4-kinase alpha 1 TSSVSSISQVS(1)PER;TSSVSSIS(0.001)QVS(0.999)PER;TSSVSSIS(0.001)QVS(0.999)PER 241.39 1.348e-27 16940800.0 21640.8 21048.0 28697.9 35858.0 30578.6 26539.300000000003 24768.199999999997 31887.4 22855.199999999997 24850.800000000003 True False 28522.124243396913 27851.35438392651 28317.34709512523 27591.492100577416 26333.289215057073 24879.79337558844 26972.52181763879 26959.93502955586 24063.279212184418 23980.78105599483 1.1893742817132646 1.1614031385755927 1.1808350624195505 1.1505668658644446 1.098099730512078 1.0374888673348224 1.1247557681569371 1.1242308983433336 1.00344017803244 1.0 14.549591027761961 -3.7198275419050697 0.1287148762316616 0.9502030732402016 1.4997017116016413 0.7131419403980006 0.03584531802670956 27.949884707863784 0.4318377700304467 0.2636254494338072 2.6481208586152523 0.0001906217525598533 3.7198275419050697 0.5494986383614398 TSSVSSISQVS(ph)PER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSSVSSISQVSPER 14 0 P42356 P42356 PI4KA Phosphatidylinositol 4-kinase alpha 1 T(0.007)S(0.001)SVSS(0.001)IS(0.006)QVS(0.986)PER;TSSVSSIS(0.007)QVS(0.993)PER;TSSVSSIS(0.001)QVS(0.999)PER 211.45 1.8865e-11 21790100.0 29563.0 26893.800000000003 31100.2 33654.8 40489.0 35288.0 35262.4 32531.9 32594.6 20198.699999999997 True False 34567.43200413457 29563.63872906771 31841.746716165322 31769.230666333748 32555.471102718442 33437.435159026354 31922.090194332144 31677.97209539724 33071.23436207506 23860.564417178757 1.4487265011739308 1.2390167395949334 1.3344926029176576 1.331453443886727 1.3644049039879234 1.4013681560253701 1.3378598106987518 1.3276287828543665 1.3860206231443943 1.0 14.542340549666994 -10.940527264553848 5.516850443399067 0.9997864685461532 1.3485040921417037 0.8021548562238636 0.052462436568973175 0.00013285514192275355 1.4024009502018909e-05 0.04897890998284834 0.011871944748903442 1.1467605267348256e-11 10.940527264553848 0.3487176235955506 TSSVSSISQVS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 4 TSSVSSISQVSPER 14 0 P42356 P42356 PI4KA Phosphatidylinositol 4-kinase alpha 1 TSSVSSISQVS(1)PER;TSSVSSIS(0.001)QVS(0.999)PER;TSSVSSISQVS(1)PER;TSSVSS(0.001)IS(0.002)QVS(0.996)PER 165.89 8.517899999999999e-05 27014500.0 36827.3 29433.5 33865.8 31355.199999999997 33198.9 30964.8 22107.6 22006.5 31632.1 21890.4 True False 36302.13594870032 29365.348539138864 31081.484649768427 33661.16600588093 31246.205973548706 29640.507686474302 23252.22335468243 23029.00232867801 28069.35979721997 25674.12647287548 1.4139579777739761 1.143772060567012 1.210615079060461 1.3110929418161001 1.2170309282600165 1.1544894319107322 0.9056675552038053 0.8969731590676697 1.0932936638321478 1.0 14.648027571197526 -7.050839208958293 3.1248413467416642 0.9662714670630722 1.2517708848690665 0.7155081024371519 0.08449340669963998 0.1398363896169203 2.718016482359458 0.033811815333269525 0.02651550318412289 8.89530392234063e-08 7.050839208958293 0.2854994178059943 TST(ph)FCGTPEFLAPEVLTDTSYTR ddPTM_PC-9_AZD4547_30min_R2 2 TSTFCGTPEFLAPEVLTDTSYTR 23 0 Q16512;Q16512-2 Q16512 PKN1 Serine/threonine-protein kinase N1 1 T(0.168)S(0.168)T(0.592)FCGT(0.072)PEFLAPEVLTDTSYTR;T(0.309)S(0.309)T(0.379)FCGT(0.004)PEFLAPEVLTDTSYTR 124.97 1.3256e-05 0.0 8025.6 7230.6 11186.0 10823.7 7308.4 7715.5 11332.2 7766.9 7724.5 5830.9 True False 10577.573857149748 9567.750047910446 11037.666331197435 8328.463189498023 6293.754812166782 7233.048565310786 12340.74384661971 6566.704070606493 8132.801300120699 5626.761965787832 1.8798687276028614 1.7004007111167738 1.9616373321475657 1.480152037732755 1.1185393749432515 1.2854726411548225 2.193223015591316 1.167048492638173 1.44537859421995 1.0 12.458089217661046 -1.5228787452807238 0.04879296831974162 1.627335382153247e-13 4.321191839762018 0.3184384182484382 0.3120302796408321 696.5028145978501 2.578011934086723 54.83965947893126 228.98791685510037 0.029999999999973322 1.5228787452807238 4.321191839761855 TST(ph)SPPPEK ddPTM_PC-9_AZD4547_30min_R2 1 TSTSPPPEK 9 0 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 T(0.004)S(0.003)T(0.886)S(0.108)PPPEK 110.53 0.0056125 197170000.0 183910.0 208640.0 205060.0 165910.0 213130.0 250440.0 238690.0 282270.0 229720.0 206240.0 True False 242389.55443436088 276078.7998224262 202340.77041617627 127662.01278394798 183540.57839159132 234779.94720969914 259932.9475962 238651.65741931685 241862.53021732537 199019.60037456988 1.2179180039461714 1.3871940216080483 1.0166876530520395 0.6414544725427971 0.9222236304673214 1.1796825376386324 1.3060670763431672 1.199136451737198 1.215269901869574 1.0 17.602550995510775 -6.895505654949548 8.01955128030187 1.203112024923813 1.033813238901214 0.11460173368776039 0.19429985002698147 0.5531076040992502 38.19572495420201 0.07764235647377463 0.0684869749658604 1.272021186986762e-07 6.895505654949548 -0.16929878602259896 TST(ph)SPPPEK ddPTM_PC-9_Lapatinib_30min_R1 1 TSTSPPPEK 9 0 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 T(0.007)ST(0.496)S(0.496)PPPEK 101.97 0.0081327 227410000.0 90244.0 119680.0 87306.0 88087.0 100430.0 100770.0 99706.0 103780.0 90382.0 83988.0 True False 88957.10401127742 119402.88831311729 80128.03769090612 94565.21182961807 94522.90485297694 96460.30200634326 104868.2888147951 108601.99766751683 80202.22739534645 98505.21389302453 0.9030700050850482 1.2121479015596817 0.81343955841692 0.9600020962577144 0.9595726065386515 0.9792405720888844 1.0645963261262577 1.1024999934060067 0.8141927135191555 1.0 16.587912468164504 -7.027742302937412 24.231018227731436 1.006443141012792 0.9734549448045173 0.0065074396704918325 0.1172678312422648 3082.977961534265 2692762.3158519715 0.04389489828343454 0.034098348153385416 9.381184926297612e-08 7.027742302937412 -0.032988196208274756 TST(ph)SSSSVQAR ddPTM_PC-9_AZD4547_30min_R2 1 TSTSSSSVQAR 11 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 T(0.031)S(0.151)T(0.766)S(0.046)S(0.003)S(0.003)S(0.001)VQAR 106.79 0.0031855 0.0 4230.2 3544.7 7146.3 11756.0 7298.0 6053.0 4703.4 6659.5 4579.1 4810.2 True False 5575.315606373966 4690.454954613467 7051.535392690534 9045.83582838943 6284.798672649717 5674.504953123739 5121.993488306874 5630.427295086062 4821.14187758207 4641.796362110931 1.2011116325315276 1.0104827072768026 1.5191393250788225 1.9487791197017725 1.3539582916540538 1.2224803740729304 1.10345070932357 1.2129845550840872 1.0386370925133774 1.0 12.180467516991854 -6.870829059592143 3.005557918932679 1.1115770157420963 1.4225992025067011 0.2951125666597798 0.2315829319733881 0.39787187362616655 7.212036936714545 0.09900113051226835 0.08657524941023514 1.3463901954656633e-07 6.870829059592143 0.3110221867646048 TSTDRHS(ph)LSLDDIR ddPTM_PC-9_AZD4547_30min_R2 2 TSTDRHSLSLDDIR 14 1 Q96NE9-3;Q96NE9-2;Q96NE9 Q96NE9-3 FRMD6 FERM domain-containing protein 6 1 T(0.197)S(0.197)T(0.197)DRHS(0.292)LS(0.116)LDDIR;T(0.004)S(0.004)T(0.013)DRHS(0.932)LS(0.047)LDDIR 81.278 0.005005600000000001 25888000.0 46388.0 36441.0 98971.0 163590.0 133406.0 113722.0 71356.0 131006.0 75061.0 90087.0 True False 61138.419069659925 48219.84060740521 97658.57987349748 125876.85294030518 114884.87965518064 106610.94536248762 77706.54576511131 110762.03291839412 79028.5712199314 86933.08155034884 0.7032813973613776 0.5546776871066952 1.123376488350258 1.4479741278629512 1.3215323511641885 1.2263564509759382 0.8938662288199939 1.2741068295645808 0.9090736208880459 1.0 16.407617664834618 -5.292412560645957 7.0401168627372295 1.1708271140439745 0.628598904498135 0.5886626588890624 0.1733927169657052 0.12384076693455626 22.55470192597478 0.04667691683962832 0.1010422970152729 5.1002027296216925e-06 5.292412560645957 -0.5422282095458395 TSTDRHS(ph)LSLDDIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSTDRHSLSLDDIR 14 1 Q96NE9-3;Q96NE9-2;Q96NE9 Q96NE9-3 FRMD6 FERM domain-containing protein 6 1 T(0.007)S(0.009)T(0.009)DRHS(0.844)LS(0.132)LDDIR 78.22800000000001 0.006698899999999999 7879800.0 20082.0 25107.0 36151.0 35315.0 38815.0 32541.0 37301.0 34058.0 29845.0 21438.0 True False 23481.485962420295 27599.457033617535 37012.976943430986 33336.415042774766 31209.47938580891 30834.492674843474 33767.57924414625 33164.01358743388 30281.42666380718 25324.539696885393 0.9272226166190981 1.0898305502868402 1.4615458913151786 1.316368054139785 1.2323809142974194 1.2175736674351376 1.3333936035291194 1.309560370469938 1.1957345336283218 1.0 14.628248426145225 -5.01857216135559 5.841422459877304 1.27260777067642 0.9606456624115147 0.46069108217248467 0.11352387856267114 0.11243504928713888 14.369505011898763 0.027529458982897242 0.08794148331859608 9.581375011925774e-06 5.01857216135559 -0.31196210826490534 TSTDRHS(ph)LSLDDIR ddPTM_PC-9_Lapatinib_30min_R1 2 TSTDRHSLSLDDIR 14 1 Q96NE9-3;Q96NE9-2;Q96NE9 Q96NE9-3 FRMD6 FERM domain-containing protein 6 1 T(0.062)S(0.062)T(0.167)DRHS(0.659)LS(0.051)LDDIR;T(0.01)S(0.01)T(0.008)DRHS(0.903)LS(0.069)LDDIR 61.167 0.025036000000000003 16889900.0 70573.0 44839.0 81104.0 43426.0 70671.0 94879.0 57971.0 69580.0 101401.0 53943.0 True False 69566.61607849698 44735.17805039993 74435.94219049362 46619.69290488933 66514.27072453177 90821.24634375153 60972.45472571855 72812.94081427848 89980.1515801323 63266.975675470625 1.099572333524215 0.707085767460579 1.1765370700239326 0.736872474259337 1.0513268575649675 1.4355237527019018 0.9637327227158466 1.1508838542840123 1.4222293798535197 1.0 15.949165012508509 -6.525448956533601 24.9989096353648 1.1954764808115697 0.9270015551030784 0.2912683409484128 0.1948088714823297 98.51774850335357 958206.1985484584 0.06049711952153594 0.060840736723615 2.982298042557386e-07 6.525448956533601 -0.2684749257084913 TSTPS(ph)PQPSK ddPTM_PC-9_AZD4547_30min_R2 2 TSTPSPQPSK 10 0 Q8IY18 Q8IY18 SMC5 Structural maintenance of chromosomes protein 5 1 TST(0.199)PS(0.8)PQPSK;T(0.021)S(0.025)T(0.131)PS(0.814)PQPS(0.009)K 107.39 0.0021795 7915100.0 45706.0 50170.0 63103.0 70496.0 64512.0 66769.0 65946.0 69967.0 60634.0 61604.0 True False 60239.55725614113 66386.47137217756 62266.21298923224 54244.23635234281 55555.62235817733 62593.92387495769 71815.06624567021 59155.207831712054 63838.9894532356 59447.26271079829 1.0133276875875217 1.1167288171894043 1.047419345313639 0.9124766032749497 0.934536256588412 1.0529319773639942 1.208046644553499 0.9950871601858771 1.0738760128250542 1.0 15.859322761186078 -6.989176673222777 24.96961555738096 1.0776496639195283 1.0068779487129285 0.13792879756757825 0.07600065923763483 429.79473039668096 991539.7112887149 0.028565421924318414 0.025168860499545982 1.025234770643414e-07 6.989176673222777 -0.07077171520659986 TSTPS(ph)PQPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSTPSPQPSK 10 0 Q8IY18 Q8IY18 SMC5 Structural maintenance of chromosomes protein 5 1 T(0.002)S(0.001)T(0.043)PS(0.954)PQPSK 89.301 0.009437000000000001 2492000.0 19080.0 33571.0 27401.0 24748.0 29544.0 19834.0 20231.0 20666.0 17952.0 16809.0 True False 22309.867152822386 36903.707016990214 28054.343758871193 23361.449794098553 23755.06528337855 18793.870124238518 18314.57322024404 20123.53939743696 18214.514038152687 19856.338640029204 1.1235639942122568 1.8585353365496358 1.4128658997744576 1.176523538282292 1.1963467038928186 0.9464922242185771 0.922353992458758 1.013456698248946 0.917314836756123 1.0 14.277312004790144 -6.095874538060494 1.340842417763556 0.9635562774918872 1.5144326867908426 0.585983783333652 0.1777039803212775 0.28098914617022663 1.0227946095023432 0.06378377583347354 0.10576127143767423 8.019096910468175e-07 6.095874538060494 0.5508764092989554 TSTPS(ph)PQPSK ddPTM_PC-9_Lapatinib_30min_R1 1 TSTPSPQPSK 10 0 Q8IY18 Q8IY18 SMC5 Structural maintenance of chromosomes protein 5 1 T(0.288)S(0.004)T(0.059)PS(0.649)PQPSK 75.08800000000001 0.024987 4005500.0 26485.0 35575.0 40039.0 32911.0 41589.0 41699.0 37450.0 36888.0 39265.0 31914.0 True False 26107.31904324584 35492.6282732215 36747.147975009546 35331.38472787759 39142.81678711997 39915.63097511666 39388.97775574267 38601.95114626471 34842.56222121966 37430.292377268044 0.697491720879562 0.9482327286007705 0.9817488894991004 0.9439248930188653 1.0457523652925556 1.0663991232768997 1.0523288826796384 1.0313024209692851 0.9308653501830526 1.0 15.191918697078995 -4.241817723410455 1.2495159504421223 1.0158679016224141 9.568655200313215e-15 0.8234361079987158 0.04275903531275365 1.972226443875524 1.0459704825468858 0.01334812133206024 3.5892858048267495 5.730364881518938e-05 4.241817723410455 -1.0158679016224046 TSTS(ph)LGK ddPTM_PC-9_AZD4547_30min_R2 2 TSTSLGK 7 0 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 T(0.011)S(0.001)T(0.08)S(0.909)LGK;T(0.002)ST(0.122)S(0.875)LGK 85.86200000000001 0.019 301420000.0 1942730.0 1166990.0 1349210.0 2061600.0 1903440.0 1768710.0 1728910.0 1554850.0 2374500.0 2548900.0 True False 2560477.7287057075 1544196.6957667407 1331318.5938418463 1586329.9714024882 1639180.2117660162 1658112.284097056 1882779.6406575323 1314583.659398541 2500011.2223621747 2459663.7868247787 1.040986878947009 0.6278080378457619 0.5412603954138252 0.6449377268144068 0.6664245010014404 0.6741215173304401 0.7654621947693283 0.5344566466523294 1.0164036384783635 1.0 21.230029695364223 -8.277209150860367 24.617581319144826 1.0082019615090336 0.6802129378448747 0.47472146203894217 0.13502976602786623 633.7975329269568 989385.0999204741 0.12550056346366978 0.03286465420107437 5.281908203369346e-09 8.277209150860367 -0.32798902366415894 TSTS(ph)LGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSTSLGK 7 0 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 TST(0.076)S(0.924)LGK;T(0.003)ST(0.119)S(0.878)LGK 96.03399999999999 0.012934999999999999 213840000.0 451570.0 699320.0 667840.0 791950.0 1297060.0 1480460.0 970100.0 1336370.0 1386310.0 1344150.0 True False 528011.8820859531 768743.86795513 683763.8383973034 747579.6090365427 1042910.4040231179 1402822.0713991183 878205.1050842153 1301291.7035010573 1406582.1611091471 1587833.7547144538 0.3325359978764953 0.4841463192684023 0.43062684387904776 0.4708173049079579 0.6568133476987762 0.8834817040725986 0.5530837863074313 0.8195390100741835 0.8858497666603001 1.0 20.598628440366625 -6.042428361988627 0.25112350966966457 1.0365213416756551 0.07429910823558948 0.8016953431793914 0.09749377087291604 2.3519198404631307 0.22251773766156804 0.16983932420208217 0.6990488291001685 9.069255519894459e-07 6.042428361988627 -0.9622222334400656 down TSTS(ph)LGK ddPTM_PC-9_Lapatinib_30min_R1 1 TSTSLGK 7 0 Q9BW04;Q9BW04-2 Q9BW04 SARG Specifically androgen-regulated gene protein 1 T(0.001)ST(0.32)S(0.679)LGK 81.525 0.023815 160390000.0 468010.0 550590.0 548150.0 496940.0 798160.0 564510.0 880990.0 834910.0 830060.0 747370.0 True False 461336.09157747735 549315.1426831487 503083.22292019037 533486.6253432446 751213.7980429353 540367.2232370828 926603.3514828244 873702.9665888043 736569.9018806969 876551.9086920727 0.5263077828052986 0.6266772534929471 0.5739343191561292 0.6086195467183168 0.8570100533622044 0.6164691650074434 1.0571003751111954 0.9967498307002497 0.8403038024065832 1.0 19.74148000317995 -6.753673849575283 0.8850951098675893 0.9776134401245017 0.5673564912647768 0.7073862301334874 0.10366251020022918 0.31981045424998333 0.5443763851194734 0.06386606872923285 0.05993615912399951 1.7632997682156786e-07 6.753673849575283 -0.41025694885972486 TSTS(ph)PPPEK ddPTM_PC-9_AZD4547_30min_R2 1 TSTSPPPEK 9 0 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 T(0.001)S(0.001)T(0.003)S(0.996)PPPEK 109.83 0.0023425 209530000.0 75008.0 98570.0 99486.0 93919.0 94784.0 112870.0 94958.0 107420.0 99053.0 75866.0 True False 98858.98373667886 130430.8248585916 98166.75063700248 72267.42558408533 81624.87769093327 105812.22105717438 103409.07804197886 90820.7072660329 104288.73935929257 73209.95443181304 1.350348931425098 1.7815995908052842 1.3408934809327595 0.98712567361853 1.1149423370691727 1.4453255964764566 1.4125002377687992 1.240551342654124 1.4245158348845304 1.0 16.159752206105395 -5.507497918350712 24.469922157985643 1.2467777639145978 1.5647924131454036 0.33899451714345896 0.18363147388925152 585.6286177678462 931695.83022978 0.04922281530522681 0.09742461235903954 3.1081508006133035e-06 5.507497918350712 0.3180146492308058 TSTS(ph)PPPEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSTSPPPEK 9 0 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 T(0.157)S(0.005)T(0.022)S(0.817)PPPEK 81.017 0.017845 216160000.0 89402.0 129060.0 91645.0 86214.0 86798.0 72037.0 86014.0 51906.0 61062.0 56627.0 True False 104535.99283001204 141872.22387217404 93830.16436559815 81383.70908955942 69790.5549846564 68259.25290610925 77866.1312325674 50543.52249895304 61954.91623204538 66893.02684091452 1.5627337820819545 2.120882109424882 1.4026897689761553 1.2166247056379544 1.0433158474146011 1.0204240431284997 1.1640395854376449 0.7555873143422858 0.9261789929073925 1.0 16.029568206763486 -5.667604619234404 1.810724901109561 0.9870929883826467 1.847815068546877 0.7870235559163622 0.17187253459862906 0.14710079117253386 0.9708712274280509 0.05131808477231518 0.11802165879082951 2.149786744748377e-06 5.667604619234404 0.8607220801642304 TSTS(ph)PPPEK ddPTM_PC-9_Lapatinib_30min_R1 1 TSTSPPPEK 9 0 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 TST(0.028)S(0.972)PPPEK 91.65799999999999 0.0076307 203170000.0 73570.0 101980.0 76768.0 72654.0 91766.0 95258.0 93177.0 88616.0 79892.0 77541.0 True False 72520.87830891427 101743.87157563258 70456.43137304968 77997.21752663892 86368.50429889762 91184.03739724374 98001.2491414375 92733.42286861283 70893.72165994346 90943.85853311219 0.797424691217712 1.1187547264512443 0.7747244564886903 0.8576413931045221 0.9496903440428723 1.0026409574874602 1.0776016184287558 1.0196776820817326 0.7795328107189495 1.0 16.472688595073443 -6.485618351704001 5.4821786328065425 0.9829957746110928 0.8960094200518205 0.11778044722137393 0.11309488566295865 0.4584096747889401 36.66526176308906 0.03616557397774605 0.03985258252455157 3.2687495640958013e-07 6.485618351704001 -0.08698635455927228 TSTS(ph)SSSVQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSTSSSSVQAR 11 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 T(0.001)S(0.017)T(0.063)S(0.817)S(0.049)S(0.049)S(0.003)VQAR 101.56 0.0091542 0.0 4701.1 7921.1 6662.9 8148.6 9751.0 8401.4 9696.3 9353.0 6740.6 6783.4 True False 5496.903379042625 8707.45445927382 6821.76880518896 7692.060360117641 7840.36154813919 7960.815794180571 8777.796268867198 9107.493660322649 6839.1685230376515 8013.176722635149 0.6859830463385758 1.0866420098632688 0.8513189015186985 0.9599264594264547 0.9784336249557805 0.9934656466134495 1.095420277462769 1.136564682842491 0.853490289777183 1.0 12.96815857890998 -4.750988228648894 24.924459722508033 0.9962786007207634 0.685982374984155 0.51561677271494 0.08985451378210814 357.6532489162762 852891.3907042095 0.0225932801351578 0.31246322667517795 1.7742375701273417e-05 4.750988228648894 -0.3102962257366083 TSTS(ph)SSSVQAR ddPTM_PC-9_Lapatinib_30min_R1 1 TSTSSSSVQAR 11 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 T(0.002)S(0.002)T(0.007)S(0.911)S(0.039)S(0.039)S(0.002)VQAR 130.44 0.00020925 1259700.0 5793.8 7306.5 8027.0 6238.1 6616.2 5384.2 6087.9 7588.2 7994.2 5638.8 True False 5711.179349547204 7289.582248160024 7367.051045116052 6696.870683691572 6227.048123949676 5153.930317183222 6403.101673676527 7940.775474086044 7093.809013342013 6613.459066771288 0.8635691688548425 1.10223442446115 1.1139482335546789 1.0126124038990998 0.9415720368236498 0.7793093243864874 0.9681925311745434 1.2006992700663612 1.0726321795781875 1.0 12.691189332972902 -10.385519791373651 4.571047560018823 0.9999999474429425 1.0083199100828621 0.0 0.11857727478816979 6.902353328294749e-08 1.7063639585124375e-08 0.12462789542138852 0.030226513537853036 4.116045895100993e-11 10.385519791373651 0.008319962639919631 TSTSS(ph)SSVQAR ddPTM_PC-9_Lapatinib_30min_R1 1 TSTSSSSVQAR 11 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 T(0.001)S(0.003)T(0.078)S(0.057)S(0.356)S(0.356)S(0.148)VQAR 85.522 0.0325 0.0 6524.6 4078.1 5352.4 4502.2 5412.4 3985.5 4465.1 4197.7 5026.7 4499.8 True False 6431.5580075349035 4068.657410007718 4912.346332861488 4833.306806898926 5094.053273187815 3815.0494556542717 4696.28103009791 4392.740466457261 4460.540112502353 5277.584434393393 1.2186556345022548 0.7709317511800966 0.930794456048549 0.9158179972263139 0.9652244007676073 0.7228779573457974 0.8898542673221488 0.8323392114449731 0.8451859307893855 1.0 12.365662039637872 -4.75112879200096 24.99585868899516 0.8711245702708978 1.2186563525829999 0.6185180579161482 0.0809723853726748 280.39942510537327 679724.0827767341 0.019467812146888926 0.26668579306735685 1.773663414949589e-05 4.75112879200096 0.347531782312102 TSTTGVATTQS(ph)PTPR ddPTM_PC-9_AZD4547_30min_R2 1 TSTTGVATTQSPTPR 15 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 TSTTGVATT(0.001)QS(0.993)PT(0.007)PR 281.68 6.393599999999999e-76 37440000.0 88246.0 83918.0 115340.0 122080.0 116160.0 118210.0 90008.0 124220.0 126470.0 111690.0 True False 116306.39236917316 111042.85239406802 113810.51623818271 93936.34211719816 100033.18906755133 110818.31001301103 98018.53763139962 105024.65329162688 133154.94600637772 107779.76709579011 1.0791115577917787 1.0302754903466975 1.0559543716311126 0.8715582214397578 0.9281258603819958 1.0281921458831915 0.9094335632056514 0.9744375602360079 1.2354354587539165 1.0 16.717726848721796 -8.221823550737657 24.831173781139245 1.117717820053526 0.981826840614301 0.2951866000471326 0.08216416913605792 507.953607734918 318385.67359423224 0.055227539615949124 0.02087342289902923 6.00034814547477e-09 8.221823550737657 -0.135890979439225 TSTTGVATTQS(ph)PTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSTTGVATTQSPTPR 15 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 TSTTGVATTQS(0.97)PT(0.03)PR;TSTTGVATTQS(0.996)PT(0.003)PR 224.67 2.9611999999999997e-24 48944000.0 110810.0 171922.0 153520.0 175162.0 230510.0 222550.0 171372.0 182472.0 172760.0 167950.0 True False 129567.94440273836 188989.27996708464 157180.499027842 165348.24102286613 185343.22022988016 210879.08622311565 155138.40353416378 177682.30334506542 175286.2881701904 198398.0055085315 0.6530708011435462 0.9525765114556948 0.7922483828653354 0.8334168511374266 0.9341990094850527 1.0629093053762955 0.7819554593631867 0.8955851289413529 0.8835083181451275 1.0 17.59803799684802 -4.753412625159221 24.996706521262553 0.8971722217892305 0.6530703554317309 0.4420316887466741 0.08427387047424596 294.3573615042823 916607.367282989 0.021079326174271877 0.22747726860147194 1.764360696981414e-05 4.753412625159221 -0.24410186635749964 TSTTGVATTQS(ph)PTPR ddPTM_PC-9_Lapatinib_30min_R1 2 TSTTGVATTQSPTPR 15 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 TSTTGVATTQS(0.774)PT(0.226)PR;TSTTGVATT(0.002)QS(0.961)PT(0.036)PR 228.49 1.5632e-24 56743000.0 168735.0 203564.0 220280.0 192396.0 297100.0 229650.0 294490.0 342130.0 289210.0 285540.0 True False 166328.80795779044 203092.66006493493 202169.4287053898 206545.44365424107 279625.16212107404 219828.40484029683 309737.2512493637 358026.60880697024 256636.12428368602 334895.20854186657 0.49665926449645525 0.6064364460429285 0.6036796691885659 0.616746487814919 0.8349631615769056 0.6564095252285916 0.9248781211231998 1.0690705620000291 0.7663176950219129 1.0 18.353350209507006 -6.60087309808983 0.6011317604141835 0.974410261293493 0.5186898089848149 0.7106253858428981 0.09838865600597706 0.4711318305897493 0.37333465867542687 0.07603602726599132 0.10154521617319728 2.506841651286444e-07 6.60087309808983 -0.4557204523086781 TSTTGVATTQSPT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 TSTTGVATTQSPTPR 15 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 TSTTGVATTQS(0.209)PT(0.791)PR 181.97 2.4035999999999998e-05 26045000.0 100160.0 92191.0 109930.0 138590.0 126080.0 129730.0 99146.0 118740.0 120350.0 122200.0 True False 132008.7965425784 121989.93785673539 108472.25637301407 106640.21669415552 108575.96829921556 121617.96259189554 107969.80192874788 100391.4613737548 126711.45530060526 117921.8151947853 1.1194603502712708 1.0344984738848388 0.919865897534207 0.9043298436171913 0.9207453949031219 1.0313440510647236 0.9156049858154023 0.8513391793361258 1.0745378630010154 1.0 16.84747111185522 -4.989479009453928 3.0170516930274527 0.9459050215011184 1.1184597670971734 0.4105380124652267 0.06324927030835918 0.25373244507173676 4.366172930012939 0.016133120782934888 0.08361936671634926 1.0245212968082544e-05 4.989479009453928 0.172554745596055 TSTTLS(ph)SEEK ddPTM_PC-9_Lapatinib_30min_R1 1 TSTTLSSEEK 10 0 O96028;O96028-4;O96028-2 O96028 WHSC1 Histone-lysine N-methyltransferase NSD2 1 TS(0.001)T(0.001)T(0.005)LS(0.843)S(0.15)EEK 82.029 0.038841 0.0 32969.0 38185.0 35466.0 26079.0 36026.0 34909.0 37225.0 36877.0 28011.0 29807.0 True False 32498.85601422588 38096.58497857941 32550.12238271906 27996.93665699371 33907.021509841165 33416.02344685361 39152.32835667611 38590.44004610723 24856.106211093433 34959.10023466905 0.9296250703270864 1.0897472967796495 0.9310915373742656 0.8008483190087672 0.9699054404213603 0.9558605119280167 1.1199466832343876 1.103873949474162 0.7110053189081667 1.0 15.093380433275671 -7.025248517464709 24.573653657358115 0.9988684902942432 0.9455552714845774 0.01666062506228716 0.12302028487720387 2537.4380533373974 2469608.1842440283 0.04775519982698573 0.03716398856167908 9.43520808404041e-08 7.025248517464709 -0.053313218809665774 TSVATSTEGKDKDVTLS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 1 TSVATSTEGKDKDVTLSPVK 20 2 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 T(0.001)S(0.001)VAT(0.001)S(0.001)T(0.001)EGKDKDVT(0.014)LS(0.981)PVK 61.345 0.033665 21174000.0 36786.0 28201.0 39987.0 48543.0 38946.0 45061.0 33705.0 38419.0 37182.0 41700.0 True False 48483.182803667136 37316.42174938762 39456.74625295832 37352.16133187378 33539.020156894454 42243.32854662295 36704.679704763184 32482.226330792306 39147.364611442565 40240.095692492156 1.2048476021072918 0.9273442596795309 0.9805331119110636 0.9282324181660135 0.8334726739517182 1.0497820101979665 0.9121419587382195 0.807210464383978 0.9728447196199519 1.0 15.296346115481153 -4.761159136329403 24.999999913966256 0.929564278530233 1.2048479080083323 0.5750412695513694 0.06956925010332606 4.735835892346797 421739.96866523067 0.01707357200172266 0.09663557654418543 1.7331688051108917e-05 4.761159136329403 0.27528362947809926 TSVLGGGEDGIEPVS(ph)PPEGMTEPGHSR ddPTM_PC-9_AZD4547_30min_R2 8 TSVLGGGEDGIEPVSPPEGMTEPGHSR 27 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 TSVLGGGEDGIEPVS(0.755)PPEGMT(0.212)EPGHS(0.033)R;TSVLGGGEDGIEPVS(0.995)PPEGMT(0.004)EPGHS(0.001)R;TSVLGGGEDGIEPVS(0.931)PPEGMT(0.063)EPGHS(0.006)R;TSVLGGGEDGIEPVS(1)PPEGMTEPGHSR;TSVLGGGEDGIEPVS(0.998)PPEGMT(0.002)EPGHSR;TSVLGGGEDGIEPVS(0.987)PPEGMT(0.006)EPGHS(0.007)R;TSVLGGGEDGIEPVS(0.996)PPEGMT(0.004)EPGHSR;TSVLGGGEDGIEPVS(0.983)PPEGMT(0.017)EPGHSR 115.67 4.1169e-12 102711500.0 39679.200000000004 35542.2 56390.5 60838.3 54852.200000000004 62576.4 48542.700000000004 65207.700000000004 53559.9 54607.3 True False 52296.36022136871 47030.521084397194 55642.72512510186 46812.96987736516 47236.918847892135 58663.4878157364 52862.906260329524 55131.348288878085 56390.96696929702 52695.51504816854 0.9924252599782929 0.8924957093864057 1.0559290496399798 0.8883672516451127 0.8964125088200249 1.1132539033371736 1.0031765741734942 1.0462246784851228 1.0701283955143146 1.0 15.685392557861485 -6.75531032966442 24.99999634542503 1.0467344955421378 0.9452045206351201 0.4461209769187443 0.05650917730183908 139.3781685656245 568514.3191203034 0.018441982145762904 0.01798597741079168 1.7566679199419274e-07 6.75531032966442 -0.10152997490701776 TSVLGGGEDGIEPVS(ph)PPEGMTEPGHSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TSVLGGGEDGIEPVSPPEGMTEPGHSR 27 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 TSVLGGGEDGIEPVS(0.912)PPEGMT(0.083)EPGHS(0.005)R;TSVLGGGEDGIEPVS(0.998)PPEGMT(0.002)EPGHSR;TSVLGGGEDGIEPVS(0.948)PPEGMT(0.039)EPGHS(0.013)R;TSVLGGGEDGIEPVS(0.978)PPEGMT(0.017)EPGHS(0.005)R 109.52 2.224e-10 77189000.0 34077.200000000004 45419.3 46866.9 52641.899999999994 60039.7 47404.0 48141.2 35826.5 39217.8 38549.399999999994 True False 39845.7969046205 49928.22793830342 47984.38463970802 49692.545010342474 48275.35178359268 44918.05079002734 43580.917023894595 34886.09233631449 39791.28613221167 45538.1010631175 0.8749990881128914 1.0964055762690024 1.0537194902615696 1.0912300655986238 1.0601090220402747 0.9863839233825155 0.9570209562205904 0.7660857945736708 0.8738020515405215 1.0 15.474786511956289 -7.35129900084095 2.4376484207426765 0.8661886861324001 1.0394408970568805 0.38647575992544414 0.08088788987867256 0.26090071736946974 3.02755819845366 0.03904604486844558 0.024109855476940084 4.4534953086151406e-08 7.35129900084095 0.1732522109244804 TSVLGGGEDGIEPVS(ph)PPEGMTEPGHSR ddPTM_PC-9_Lapatinib_30min_R1 9 TSVLGGGEDGIEPVSPPEGMTEPGHSR 27 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 TSVLGGGEDGIEPVS(1)PPEGMTEPGHSR;TSVLGGGEDGIEPVS(0.964)PPEGMT(0.033)EPGHS(0.003)R;TSVLGGGEDGIEPVS(0.981)PPEGMT(0.017)EPGHS(0.002)R;TSVLGGGEDGIEPVS(0.813)PPEGMT(0.12)EPGHS(0.068)R;TSVLGGGEDGIEPVS(0.893)PPEGMT(0.099)EPGHS(0.008)R;TSVLGGGEDGIEPVS(0.995)PPEGMT(0.005)EPGHSR;TSVLGGGEDGIEPVS(0.998)PPEGMT(0.002)EPGHSR;TSVLGGGEDGIEPVS(1)PPEGMTEPGHSR;TSVLGGGEDGIEPVS(0.994)PPEGMT(0.006)EPGHSR 127.65 3.7741e-12 95953000.0 64890.8 98868.1 110025.7 94559.5 123276.6 110673.3 103406.4 116761.9 113637.6 95480.6 True False 63965.445292484685 98639.17698888796 100979.811657484 101513.72107124476 116025.7127591207 105940.0609510632 108760.27742059893 122187.08413427274 100838.53683102176 111984.29449009748 0.571200145375216 0.8808304542884842 0.9017319090795666 0.9064996259830113 1.0360891523889593 0.9460260604707497 0.9712100961641219 1.0911091121360545 0.9004703497947981 1.0 16.772936886629886 -4.3514094975347914 1.0790731131575833 0.9830921390206218 1.8562263966032542e-25 0.8164006001984457 0.05693293045583301 1.5440018994523597 0.7884801978131241 0.017272406220843174 2.170019950136785 4.452362358665558e-05 4.3514094975347914 -0.9830921390206218 TSVLGGGEDGIEPVSPPEGMT(ph)EPGHSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSVLGGGEDGIEPVSPPEGMTEPGHSR 27 0 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;Q9Y618-2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 TSVLGGGEDGIEPVS(0.4)PPEGMT(0.574)EPGHS(0.025)R 54.658 0.0043098 3158000.0 4789.0 6442.7 9413.1 8041.1 10840.0 6121.7 8199.2 5891.1 4657.6 5844.4 True False 5599.6831129384855 7082.28867767904 9637.544003380546 7590.583236597944 8715.979815591101 5800.6672753630555 7422.512418932575 5736.464867136404 4725.7085886864925 6903.9434557550585 0.8110847298829839 1.0258323700167786 1.3959477022290478 1.0994561709902924 1.2624639630160277 0.8401962316953331 1.0751119945435303 0.8308968495902938 0.6844941038367267 1.0 12.753204933356848 -7.311855708237188 1.349085014860025 0.8321130328431514 1.1167758790337363 0.2529077623753053 0.17947675294428433 0.5888922973071032 2.0771354809497056 0.11750775035569404 0.06548427797128802 4.876904954604934e-08 7.311855708237188 0.2846628461905849 TSVPENHAQSR ddPTM_PC-9_AZD4547_30min_R2 2 TSVPENHAQSR 11 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 ; 90.434 0.0073349999999999995 980800.0 1490.79 1570.95 7368.6 12910.3 9888.1 8741.5 5806.2 9354.8 6892.1 6897.3 False True 1964.8302096416817 2078.7288658983907 7270.887549442287 9934.02979714666 8515.307996030097 8194.892623117652 6322.940551900188 7909.230611918476 7256.402335498987 6655.827626374729 0.29520449145283495 0.3123171125497769 1.0924092325694088 1.492531110298223 1.2793762810633638 1.2312357054807344 0.9499856226511297 1.1883166235521103 1.0902329120941157 1.0 12.700402355491672 -5.280312140440315 4.725240700581252 1.1876251541188494 0.2905127777935153 0.8524295572599727 0.14362912473122177 0.06295018754780174 3.904324005327195 0.04000220687934469 0.09555261212824877 5.24430400941474e-06 5.280312140440315 -0.8971123763253341 down TSVPENHAQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSVPENHAQSR 11 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 72.29 0.023166 355180.0 1051.0 2144.8 2066.5 3472.6 4225.7 3564.3 3207.3 3359.4 3256.7 2196.1 False True 1228.9135418037897 2357.7215695106097 2115.7731972448923 3278.041480321101 3397.7044194412656 3377.3818334084553 2903.481325158851 3271.219309578522 3304.3230764289115 2594.235545681966 0.4737093144257015 0.9088309553983919 0.8155671140835838 1.2635866800057194 1.3097131542649054 1.3018794068372146 1.1192049735004272 1.260956937785922 1.273717447102622 1.0 11.341093760843707 -5.04296172385676 1.023114198947237 1.233893191376858 0.3421687637635367 0.7574925075069625 0.12843360813089819 0.5991509883360651 0.6786592054518196 0.04247723620125614 0.5325337124893819 9.058124303226397e-06 5.04296172385676 -0.8917244276133214 down TSVPENHAQSR ddPTM_PC-9_Lapatinib_30min_R1 2 TSVPENHAQSR 11 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 ; 96.745 0.0047652 1259480.0 6698.3 5988.8 8124.6 5893.9 8229.8 8175.700000000001 6921.0 8309.0 10893.5 6492.6 False True 6602.7810136822245 5974.933301550774 7456.626749862946 6327.357067474029 7745.739344409331 7826.044369487554 7279.335515286918 8695.066473495815 9666.55931635952 7614.837259154305 0.867094172727668 0.7846435975198166 0.9792233892981542 0.8309247922360375 1.0171903982711725 1.027736260558864 0.9559410487119658 1.1418584767577133 1.2694374137462627 1.0 12.894597489080514 -6.766435061995126 0.7159438131124726 1.136592211107383 0.8428188749422224 0.5682775788255605 0.08989917827371632 0.5080621015568572 0.571407781662609 0.06568411633621116 0.065916379744165 1.7122411809082454e-07 6.766435061995126 -0.29377333616516055 TSVPS(ph)PEQPQPYR ddPTM_PC-9_AZD4547_30min_R2 2 TSVPSPEQPQPYR 13 0 Q8TEH3 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 TS(0.003)VPS(0.995)PEQPQPY(0.002)R;TSVPS(0.999)PEQPQPYR 85.287 0.0081664 16251700.0 45007.0 38222.0 52224.0 69878.0 60470.0 56793.0 43708.0 62101.0 46832.0 58371.0 True False 59318.2897962444 50576.51402805201 51531.475637444564 53768.706704337994 52074.78428817871 53241.724731993454 47597.92732638446 52504.71738901415 49307.44391057711 56327.44905674964 1.0530973937144126 0.8979017313050413 0.9148554834344947 0.9545737931459718 0.9245010232171815 0.9452181063330716 0.84502188761344 0.9321337690282386 0.8753715060112183 1.0 15.781550516198624 -4.756145614544416 24.996439950947554 0.9182823705253281 1.0530976048258498 0.48499344022687263 0.04072648295477874 136.7282684253124 645542.3420121864 0.009600280655748174 0.07966029330649525 1.7532925420339935e-05 4.756145614544416 0.13481523430052167 TSVPS(ph)PEQPQPYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSVPSPEQPQPYR 13 0 Q8TEH3 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 T(0.109)S(0.002)VPS(0.861)PEQPQPY(0.027)R 105.19 0.0012562 10289000.0 23489.0 20970.0 23276.0 24656.0 24793.0 23404.0 16934.0 16871.0 15379.0 10863.0 True False 27465.223771102992 23051.763014098047 23830.988114721556 23274.604255830534 19934.98962803967 22176.653039612676 15329.888928456943 16428.154126302088 15603.888780790438 12832.37590853932 2.140306983434473 1.796375291559081 1.8570986608070916 1.8137408397101602 1.5534917126900802 1.728179816245501 1.1946259241249044 1.280211415515809 1.2159781549422046 1.0 13.647500689036132 -6.885542786636493 0.41269126287987856 0.983016264224338 2.100639955525401 0.889981247070245 0.11572629108683445 0.40476611442392035 0.1475125223551009 0.11743472341695695 0.1739209856763347 1.3015390817996612e-07 6.885542786636493 1.117623691301063 up TSVS(ph)PAPDK ddPTM_PC-9_AZD4547_30min_R2 2 TSVSPAPDK 9 0 O75362 O75362 ZNF217 Zinc finger protein 217 1 T(0.087)S(0.008)VS(0.906)PAPDK;T(0.001)S(0.005)VS(0.995)PAPDK 87.713 0.010678 14333300.0 139925.0 141746.0 165707.0 193855.0 198931.0 178060.0 176411.0 194805.0 166426.0 198126.0 True False 184418.23937919605 187562.62250589338 163509.61690896982 149164.72477989394 171312.86444901075 166925.88005174472 192111.2372466095 164702.36342356668 175222.93859458694 191189.66904486076 0.9645826592017592 0.9810290662822565 0.8552220301746739 0.7801923897095816 0.8960361995752705 0.8730904807025803 1.0048201778179369 0.8614605812457414 0.9164874831886058 1.0 17.544645043673775 TSVS(ph)PAPDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TSVSPAPDK 9 0 O75362 O75362 ZNF217 Zinc finger protein 217 1 T(0.022)S(0.017)VS(0.961)PAPDK;T(0.013)S(0.009)VS(0.978)PAPDK;TS(0.003)VS(0.997)PAPDK;T(0.119)S(0.012)VS(0.869)PAPDK 92.611 0.0068949 35776900.0 261437.0 318283.0 263644.0 334176.0 329934.0 269681.0 315991.0 284490.0 258748.0 226109.0 True False 305693.120483879 349880.0327809333 269930.2728354374 315453.20213320956 265285.80115103576 255538.45361373192 286058.0449032733 277022.4389420705 262531.699996877 267100.771822141 1.1444860993791366 1.3099177153030241 1.0105933838902588 1.181026920967738 0.993204921652889 0.9567117753740214 1.070974235498487 1.0371457822912478 0.982893827696213 1.0 18.027024619269312 -5.654885565592765 1.0964633382583082 1.011676090957794 1.2259186371287334 0.4936150013655569 0.0750559665220773 0.4973611232958445 1.099578140035989 0.02628197856103338 0.08788582707394896 2.2136779257420025e-06 5.654885565592765 0.2142425461709394 TSVS(ph)PAPDK ddPTM_PC-9_Lapatinib_30min_R1 2 TSVSPAPDK 9 0 O75362 O75362 ZNF217 Zinc finger protein 217 1 T(0.027)S(0.194)VS(0.78)PAPDK;T(0.025)S(0.082)VS(0.894)PAPDK 82.494 0.015693000000000002 17077000.0 128039.0 164553.0 172694.0 148705.0 170482.0 140177.0 139869.0 142451.0 169186.0 117705.0 True False 126213.14038052285 164171.98763860646 158495.7659381174 159641.26176533767 160454.5839405078 134181.95647854696 147110.7324357269 149069.79350294286 150130.49107243764 138050.1524179463 0.914255711927163 1.1892198940974468 1.148102795701899 1.15640047453207 1.1622919723748812 0.9719797778441535 1.065632524550569 1.0798234619229876 1.0875068838599915 1.0 17.074832955209544 -6.743424763069461 24.999314138583813 1.0475177163777447 1.1224742005296808 0.17057316902838282 0.07882770813255871 439.1844622837376 609466.0532449841 0.02578345002985648 0.025731598325720556 1.8054074778121397e-07 6.743424763069461 0.07495648415193612 TSVS(ph)PAPDKTK ddPTM_PC-9_AZD4547_30min_R2 1 TSVSPAPDKTK 11 1 O75362 O75362 ZNF217 Zinc finger protein 217 1 T(0.001)S(0.001)VS(0.998)PAPDKTK 117.03 0.0058038000000000005 3405300.0 6864.3 8512.6 10980.0 12476.0 11106.0 8239.6 7324.6 9743.7 7063.7 12417.0 True False 9047.004613690326 11264.131477034049 10834.398025795444 9599.85095227854 9564.123603514347 7724.376509459498 7976.475210369632 8238.035052951438 7437.072761170641 11982.284609440656 0.75503169124879 0.9400654252661645 0.9042013588342903 0.8011703331362174 0.7981886522691108 0.6446497275964871 0.6656890126015778 0.6875178917433507 0.6206723511901133 1.0 13.548615386213212 -6.358749168121975 2.0665305350104317 0.7023297303428877 0.8677631048441388 0.20405675799777256 0.11148199614555204 0.3971902590976557 3.3364424214434054 0.03699090050507165 0.044723356823295174 4.3777487417582083e-07 6.358749168121975 0.16543337450125106 TSVS(ph)PAPDKTK ddPTM_PC-9_Lapatinib_30min_R1 1 TSVSPAPDKTK 11 1 O75362 O75362 ZNF217 Zinc finger protein 217 1 T(0.015)S(0.011)VS(0.974)PAPDKTK 104.41 0.010490000000000001 0.0 10555.0 11738.0 9486.3 8639.0 7921.3 7680.7 7537.7 6753.7 6910.9 7003.3 True False 10404.48376445006 11710.821382180573 8706.37303217695 9274.340878859177 7455.384707874995 7352.214365586192 7927.965223750642 7067.501557594017 6132.521666996737 8213.811073689323 1.2667059993354306 1.425747594766692 1.0599675295753288 1.1291154368727774 0.9076644983662044 0.8951039048289023 0.9651993639281149 0.8604412122690291 0.7466109960381945 1.0 13.003836048854378 -5.701538901142742 0.9630730915253672 0.8788934525654342 1.3809014361020664 0.7703820649341238 0.09223534695958796 0.3118766544120559 0.5240275126366959 0.035511654973376314 0.12094550612340825 1.9882047125792558e-06 5.701538901142742 0.5020079835366322 TSVSQNVIPSS(ph)AQK ddPTM_PC-9_AZD4547_30min_R2 1 TSVSQNVIPSSAQK 14 0 H0Y8J2;Q03188;Q03188-2 H0Y8J2 CENPC Centromere protein C 1 TSVSQNVIPS(0.024)S(0.976)AQK 289.87 3.8622999999999996e-84 22123000.0 78105.0 83016.0 92600.0 109330.0 108050.0 108100.0 94791.0 93182.0 92568.0 99716.0 True False 102940.76531507686 109849.29853363935 91372.06349623494 84125.6576316618 93049.12257876173 101340.48991123027 103227.2153655007 78782.86300934154 97460.95549868251 96224.97319118811 1.0697926110152842 1.1415882477346213 0.9495670454975239 0.8742601306265231 0.9669955677086413 1.0531620487945286 1.072769489479617 0.8187361388275882 1.0128447144904749 1.0 16.55412374364277 -5.266465943994801 24.895496254277035 0.9653903103427478 1.1056904337076765 0.3517135774206748 0.07438167544246907 392.4959506872728 1943958.2849470624 0.020102563561742975 0.04407480238690491 5.414197026456352e-06 5.266465943994801 0.1403001233649287 TSVSQNVIPSS(ph)AQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSVSQNVIPSSAQK 14 0 H0Y8J2;Q03188;Q03188-2 H0Y8J2 CENPC Centromere protein C 1 TSVSQNVIPS(0.08)S(0.92)AQK;TSVSQNVIPS(0.063)S(0.937)AQK 227.63 1.4253000000000002e-20 22193000.0 92979.0 77570.0 75057.0 91412.0 106129.0 87724.0 88292.0 93015.0 76009.0 69583.0 True False 108718.50828104159 85270.6369577292 76846.64353525775 86290.48200170246 85333.7843034012 83123.59901072404 79928.34258127553 90573.45480753909 77120.48783009956 82197.84708127497 1.3226442314668378 1.0373828510790062 0.9348984950819199 1.049790050053024 1.0381510870841362 1.011262483900992 0.9723897330576624 1.1018957068058308 0.9382300214486754 1.0 16.32681298701062 -4.765732356975932 4.800142642037223 1.0096798143805623 1.34381509781796 0.7938176284650125 0.04810196349920531 0.07387972635846768 4.175931777944676 0.011367307232514133 0.08377112516068677 1.7150138949522725e-05 4.765732356975932 0.3341352834373976 TSVSQNVIPSS(ph)AQK ddPTM_PC-9_Lapatinib_30min_R1 2 TSVSQNVIPSSAQK 14 0 H0Y8J2;Q03188;Q03188-2 H0Y8J2 CENPC Centromere protein C 1 TSVSQNVIPS(0.079)S(0.921)AQK;TSVSQNVIPS(0.235)S(0.765)AQK 284.53 1.2396999999999999e-83 48694000.0 194632.0 210183.0 211428.0 194839.0 215326.0 216371.0 182844.0 186117.0 211800.0 163505.0 True False 191856.5119888622 209696.33417710493 194045.20597568117 209168.1100238508 202660.94802720394 207117.3167154359 192310.76765743695 194764.6752735132 187944.85364712417 191766.62139328226 1.0004687499572493 1.0934975683127448 1.0118820708517668 1.0907430526967512 1.0568103382891603 1.080048838586314 1.0028375441993043 1.015633867137297 0.9800707353636884 1.0 17.548992103337973 -7.279501866679122 23.05860015118978 1.0009383336686963 1.056967491906801 0.4573585638385379 0.02981394728373503 267.9564278566539 342070.7782387302 0.011646404632565976 0.007875962472268584 5.254097567955669e-08 7.279501866679122 0.056029158238104726 TSVTTSIS(ph)EPWTQR ddPTM_PC-9_AZD4547_30min_R2 1 TSVTTSISEPWTQR 14 0 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 TSVTT(0.016)S(0.281)IS(0.702)EPWTQR 109.55 0.0027924 0.0 8832.0 9217.1 10474.0 18453.0 14915.0 11944.0 9363.5 13824.0 12480.0 11812.0 True False 11640.39228298776 12196.347324785678 10335.107916409976 14198.945946008009 12844.30970164024 11197.139791856918 10196.833360496958 11687.81844391767 13139.667321575032 11398.46547529299 1.0212245067741061 1.0699990583137842 0.9067104636858427 1.2456892532407338 1.126845515256525 0.9823374748230401 0.8945794837558918 1.0253852563971768 1.1527575663633167 1.0 13.47655199339572 -6.777546077217538 24.979658830598577 1.0053215003528466 1.0741002970728026 0.09077962137248097 0.09900363196933354 631.1705506937467 978866.8499239787 0.036689074842245734 0.03245241190854638 1.668990723385386e-07 6.777546077217538 0.06877879671995601 TSVTTSIS(ph)EPWTQR ddPTM_PC-9_Lapatinib_30min_R1 2 TSVTTSISEPWTQR 14 0 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 TSVTT(0.002)S(0.025)IS(0.972)EPWT(0.001)QR;TSVT(0.002)T(0.05)S(0.032)IS(0.916)EPWTQR 156.2 2.3341e-05 6771200.0 18317.300000000003 20867.0 19162.4 16089.8 22678.0 21000.3 19820.5 26301.0 23627.0 15994.9 True False 18056.09194301858 20818.683743564656 17586.941441003088 17273.097565999367 21344.124626663448 20102.1661230903 20846.708507548683 27523.04047652103 20965.87845666005 18759.59715313544 0.9624989169877094 1.1097617701286866 0.9374903574655729 0.920760580571016 1.1377709474478792 1.071567046935785 1.1112556595632657 1.4671445368388887 1.1176081386777466 1.0 14.195341227050184 -6.946421454587633 1.438717004341101 1.2131191481899433 0.9977764519600909 0.2623588213627509 0.1280568213583521 0.4772507545290429 2.024834834465278 0.06352919225111585 0.049039409034951444 1.131301975274757e-07 6.946421454587633 -0.21534269622985236 TSVTTSPQS(ph)DMMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TSVTTSPQSDMMR 13 0 O60318;O60318-2 O60318 MCM3AP Germinal-center associated nuclear protein 1 TS(0.001)VT(0.081)T(0.343)S(0.138)PQS(0.437)DMMR 77.204 0.0097912 2970200.0 14325.0 12266.0 14975.0 14334.0 17686.0 14589.0 14508.0 13500.0 13522.0 10511.0 True False 16749.939568353275 13483.687416830076 15332.060793003762 13530.912451455017 14220.555260013307 13823.927157533313 13133.697211175939 13145.639304432352 13719.733668889294 12416.56109496978 1.3489998913740329 1.085943790208757 1.2348073412383977 1.0897471810400614 1.1452893559855606 1.113345881504476 1.057756419891228 1.0587182073914119 1.1049543882522719 1.0 13.59997803795388 -1.5228787452803376 0.2855120319790409 1.0438411186973762 2.8594081176442963 0.6048791842007408 0.05979179304093646 37.134618093078615 0.5255245973352441 0.060948470482096936 33.85666828388588 0.029999999999999995 1.5228787452803376 1.81556699894692 TSYAQHQQVR ddPTM_PC-9_AZD4547_30min_R2 2 TSYAQHQQVR 10 0 D6RAT0;P61247;D6RG13;D6R9B6;D6RB09;H0Y9Y4;E9PFI5;D6RAS7;H0Y8L7 D6RAT0 RPS3A 40S ribosomal protein S3a 0 ; 93.44200000000001 0.0056997 10420800.0 9246.8 10146.8 21518.2 36148.0 26947.0 23064.0 17585.6 26882.0 18744.2 27593.0 False True 12187.090054611783 13426.554668511282 21232.85460825788 27814.63708103276 23205.87418907809 21621.804433974197 19150.68433217871 22728.004586906463 19734.980144957277 26626.977468655543 0.45769708818652244 0.5042462924797457 0.7974188821563597 1.0446036210371716 0.8715174005910108 0.8120262414097401 0.7192211115483275 0.8535705794494013 0.7411648644007262 1.0 14.700601051490166 -5.275033249098575 3.998934241019542 0.8537093644022337 0.47002756340669766 0.7129720326558906 0.09563601700601491 0.11221308818752215 4.23029851774131 0.02631597550266762 0.06689851666548863 5.30843801868987e-06 5.275033249098575 -0.383681800995536 TSYAQHQQVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TSYAQHQQVR 10 0 D6RAT0;P61247;D6RG13;D6R9B6;D6RB09;H0Y9Y4;E9PFI5;D6RAS7;H0Y8L7 D6RAT0 RPS3A 40S ribosomal protein S3a 0 ;; 128.03 0.00024594 8476470.0 13139.599999999999 17385.0 30143.2 32153.8 40790.0 32495.3 29833.8 26005.800000000003 29268.2 21640.1 False True 15363.874761070481 19110.86790653764 30861.928206722583 30352.32683002611 32797.49231346503 30791.189263293723 27007.72648599262 25323.17530542275 29696.192055005606 25563.278827062637 0.6010134640790082 0.747590637172328 1.2072758121329301 1.1873409133218675 1.2829923944945543 1.2045086028125838 1.05650478832163 0.9906074833645478 1.1616738312758084 1.0 14.641785272335357 -5.150788389607749 3.9324263939214457 1.1425958021739404 0.6316609094120288 0.8045091078013434 0.09200111082904373 0.0993915756575276 2.649473041171535 0.026049466145857923 0.0802166721631846 7.066617920097568e-06 5.150788389607749 -0.5109348927619116 TSYAQHQQVR ddPTM_PC-9_Lapatinib_30min_R1 2 TSYAQHQQVR 10 0 D6RAT0;P61247;D6RG13;D6R9B6;D6RB09;H0Y9Y4;E9PFI5;D6RAS7;H0Y8L7 D6RAT0 RPS3A 40S ribosomal protein S3a 0 ; 125.68 0.00031165 13208700.0 19435.2 19289.1 25618.0 20877.0 22682.0 28897.0 23851.0 19601.8 27489.0 22370.0 False True 19158.050484020827 19244.437274068776 23511.786928339723 22412.36422363042 21347.889354527757 27661.142672197086 25085.8880761607 20512.57118788906 24392.89934799713 26236.624693848655 0.7302025587351011 0.7334951617683031 0.8961437381025698 0.8542396167630946 0.8136675202558699 1.054295016793163 0.9561400663722666 0.7818296532899053 0.9297270374003634 1.0 14.679294510684475 -5.076674029228028 0.8196956495040931 0.9211345900504897 0.6419841903209579 0.4581282550514274 0.07778549904085984 1.727719093140097 1.1975319986146904 0.03194248060369799 0.40436507390159687 8.381581470123209e-06 5.076674029228028 -0.2791503997295318 TSYQPSS(ph)PGR ddPTM_PC-9_AZD4547_30min_R2 2 TSYQPSSPGR 10 0 Q14134-2;Q14134;E9PPX1;H0YD78;E9PIQ2;H0YF27;E9PRL4 Q14134-2 TRIM29 Tripartite motif-containing protein 29 1 TSYQPS(0.116)S(0.884)PGR;TSYQPS(0.041)S(0.959)PGR 98.182 0.004857899999999999 16327700.0 86972.0 88507.0 122705.0 153389.0 144226.0 121935.0 111306.0 152543.0 123894.0 137866.0 True False 114627.28687001947 117115.15690128198 121077.85152597733 118027.53588642624 124202.70942197574 114310.38517415215 121212.01837170642 128970.98443941966 130442.78390538585 133039.35330314442 0.8616043600935801 0.8803046165928253 0.9100904996891294 0.8871625797630559 0.933578721921224 0.8592223453889143 0.9110989745681629 0.9694198087805301 0.9804826967864011 1.0 17.02149353533177 -7.763586054452841 2.7874957270159375 0.9870097153616931 0.8906655367829296 0.8041720438000861 0.02104450769224873 0.11754784665858964 1.841262756262427 0.013086955029715842 0.0059172510874095745 1.723510547538619e-08 7.763586054452841 -0.09634417857876354 TSYQPSS(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TSYQPSSPGR 10 0 Q14134-2;Q14134;E9PPX1;H0YD78;E9PIQ2;H0YF27;E9PRL4 Q14134-2 TRIM29 Tripartite motif-containing protein 29 1 TSYQPS(0.014)S(0.986)PGR;TSYQPS(0.006)S(0.994)PGR 89.35600000000001 0.0094013 11058300.0 57153.0 57577.0 66916.0 74731.0 113549.0 102769.0 91385.0 104043.0 88698.0 91362.0 True False 66827.87407679544 63292.864046863295 68511.53122034308 70544.06435117083 91299.88856831685 97379.61272551522 82728.35122989495 101311.98149267085 89995.04044986986 107925.2073788062 0.6192054266084158 0.5864511691389386 0.6348056481362576 0.6536384415141177 0.8459551830914143 0.902287937087051 0.7665340955938781 0.9387239918574016 0.8338648832426764 1.0 16.719672339384317 -6.240471582478839 2.763960078841777 0.8780995111707195 0.6126020084006397 0.8227571582844679 0.05898702302401355 0.10940350558936955 1.6685532508947898 0.01813555732619157 0.02313564088809297 5.748154299502255e-07 6.240471582478839 -0.2654975027700798 TSYQPSS(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 2 TSYQPSSPGR 10 0 Q14134-2;Q14134;E9PPX1;H0YD78;E9PIQ2;H0YF27;E9PRL4 Q14134-2 TRIM29 Tripartite motif-containing protein 29 1 TSYQPS(0.236)S(0.764)PGR;TSYQPS(0.012)S(0.988)PGR 87.21600000000001 0.010768999999999999 11314600.0 76876.0 95089.0 103306.0 84672.0 109818.0 101742.0 105426.0 108237.0 128841.0 130287.0 True False 75779.73414266817 94868.82726275088 94812.57945269195 90899.06133751175 103358.72115049517 97390.73183218593 110884.44242662011 113266.0861585952 114329.56982412233 152806.93435348486 0.4959181627671988 0.6208411134228565 0.6204730161876302 0.5948621489076994 0.6764007247956284 0.6373449755028403 0.7256505923357746 0.7412365586536753 0.7481962144443413 1.0 17.221350488559082 -14.522878745242364 0.08272632874667951 2.212656285893234 0.3082198383117779 0.9394402032860344 0.03137259973775443 50.938988414153705 0.2957953585380569 10.994386433991115 0.9434132694877951 3.0000000002623107e-15 14.522878745242364 -1.904436447581456 TT(ph)FSPPVVAATVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTFSPPVVAATVK 13 0 A0A1B0GV05;Q684P5-3;Q684P5-2;Q684P5 A0A1B0GV05 RAP1GAP2 Rap1 GTPase-activating protein 2 1 T(0.172)T(0.82)FS(0.007)PPVVAATVK 122.97 0.00042482 8671700.0 57103.0 53823.0 52731.0 63717.0 78216.0 60572.0 76666.0 77393.0 68353.0 51528.0 True False 66769.41006434051 59166.19173618497 53988.307023431145 60147.143063301155 62890.136278254016 57395.49768908818 69403.64146622639 75361.51575466165 69352.5333138286 60869.61850457642 1.0969250622019344 0.9720151561609774 0.8869499817773967 0.9881307709983274 1.0331941915082923 0.9429252079963826 1.1402016830614494 1.2380809606847738 1.139362049864242 1.0 15.893434703418727 -7.273441805384032 22.455253667393755 1.1492513356855187 0.9836686961791941 0.45416134527270413 0.07536338349252909 156.81328821387729 293377.5529233007 0.03102599907902969 0.021153647212834206 5.327926127138414e-08 7.273441805384032 -0.16558263950632468 TT(ph)GTPPDSSLVTYELHSRPEQDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTGTPPDSSLVTYELHSRPEQDK 23 1 F8VW18;F8W1I6;Q13561;Q13561-3;Q13561-2;H0YI98 F8VW18 DCTN2 Dynactin subunit 2 1 T(0.339)T(0.403)GT(0.257)PPDS(0.001)SLVTYELHSRPEQDK 70.391 0.00062951 6581200.0 60602.0 85113.0 58951.0 70907.0 88437.0 59808.0 67591.0 52373.0 61827.0 54651.0 True False 70860.72165594045 93562.45614777904 60356.615412912484 66934.31067359578 71108.40470031639 56671.563194033326 61188.291163536895 50998.2642437804 62731.102909807545 64558.79368292204 1.0976153303602616 1.4492596718474533 0.9349092814427669 1.0367961799649015 1.1014518804295275 0.8778287195447527 0.9477917363831295 0.7899506997335848 0.971689514799624 1.0 15.978326000855265 -5.609530747085624 0.8401670362014384 0.9148900831224906 1.2920149428827996 0.4171281241361373 0.12900514881060518 0.8324150472376123 0.9607164287165565 0.054000337894221824 0.23481201113433486 2.4573626492336455e-06 5.609530747085624 0.37712485976030896 TT(ph)KSPSDSGYSYETIGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTKSPSDSGYSYETIGK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.277)T(0.331)KS(0.331)PS(0.056)DS(0.004)GY(0.001)SYETIGK 84.946 0.0023921999999999997 204060000.0 84288.0 69669.0 67364.0 85414.0 100940.0 91002.0 93164.0 89484.0 84540.0 66922.0 True False 98556.2936361162 76585.27789361947 68970.21323939263 80628.53049592431 81161.53160385304 86229.69492013482 84338.83147105004 87135.13981613512 85776.2375660333 79054.42884573931 1.246689085926246 0.9687664437252724 0.8724395868316974 1.0199116187817456 1.026653823054308 1.0907636191818775 1.0668451180087875 1.102217055873794 1.085027604631872 1.0 16.270558668126817 -6.641700795293922 4.716299757434626 1.0750708187822937 1.013033660869497 0.03955091337970196 0.09121066052240628 0.5781829934550795 21.334782619081523 0.03153461637268597 0.031379460690935675 2.281913641963698e-07 6.641700795293922 -0.062037157912796737 TT(ph)KTPEDGDYSYEIIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTKTPEDGDYSYEIIEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.33)T(0.388)KT(0.282)PEDGDYSYEIIEK 71.148 0.00992 27087000.0 41611.0 40400.0 41866.0 53936.0 53286.0 50995.0 59287.0 60938.0 48780.0 41600.0 True False 48654.920445287826 44410.6450057015 42864.24421768914 50914.140782871305 42844.990816751604 48320.732428433155 53670.90615929062 59338.4420691481 49493.31521730659 49141.75069458117 0.9900933474609193 0.9037253328990299 0.8722571664996818 1.0360668894216984 0.8718653733570809 0.983292856796033 1.0921651223388116 1.2074954846020842 1.0071540903153902 1.0 15.584661634754614 -7.152724747948095 3.7366169568974996 1.0941473915178723 0.9348116333392765 0.45586048834573456 0.07195658026676956 0.19347176147924627 4.874365799870806 0.02808315768863599 0.021189503924596734 7.035180622223133e-08 7.152724747948095 -0.1593357581785958 TT(ph)PDIIKDWPR ddPTM_PC-9_AZD4547_30min_R2 1 TTPDIIKDWPR 11 1 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 T(0.209)T(0.791)PDIIKDWPR 71.806 0.043899 0.0 9144.6 11584.0 12340.0 16424.0 15112.0 15466.0 13084.0 12774.0 10826.0 11615.0 True False 12052.392580503842 15328.301462533476 12176.36353718724 12637.700548270506 13013.95965210776 14498.908575088672 14248.450652933436 10800.071817318027 11398.240258282956 11208.362385330847 1.0753036140478145 1.3675772548712983 1.0863641911795503 1.1275242639201541 1.1610937623804902 1.2935795682395483 1.2712339379373887 0.9635726831470779 1.0169407328585855 1.0 13.452287885957935 -7.7687255772834005 24.99999618813939 0.9926924691727995 1.1993911115177067 0.5264215457086092 0.0886640511872816 136.01171718763587 466666.58842017705 0.04743569537841139 0.02351718465139934 1.7032344110184938e-08 7.7687255772834005 0.2066986423449072 TT(ph)PDQELAPASEPVWERPWSVEEIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTPDQELAPASEPVWERPWSVEEIR 25 1 E7ESD2;Q641Q2-2;Q641Q2;A0A087WYF6;Q5T1D7 E7ESD2 FAM21A WASH complex subunit FAM21A 1 T(0.484)T(0.516)PDQELAPASEPVWERPWSVEEIR 52.685 0.009895399999999999 834050.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TT(ph)PDQELVPASEPVWERPWSVEEIRR ddPTM_PC-9_Lapatinib_30min_R1 1 TTPDQELVPASEPVWERPWSVEEIRR 26 2 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;Q9Y4E1-5;A0A0A0MT65 J3KP36 FAM21C WASH complex subunit FAM21C 1 T(0.48)T(0.52)PDQELVPASEPVWERPWSVEEIRR 52.577 0.005674 3715600.0 5884.4 7059.3 5950.2 4369.5 6590.6 6447.4 5906.4 5857.2 4782.9 5045.9 True False 5800.487376933204 7042.954624572103 5460.997524436217 4690.847606224704 6202.953865618137 6171.659731623477 6212.204491762843 6129.346894759859 4244.19943583017 5918.077091760877 0.9801304185456826 1.190074836026938 0.9227655266672675 0.7926303651493967 1.0481367122192213 1.0428488233476438 1.049699825710525 1.035699062334472 0.7171585246395197 1.0 12.530912774566126 -8.226744062702396 24.978575871480334 0.8585790552246482 1.0077371059845002 0.21127656955274765 0.11528557057951222 826.9271813139916 595340.4200493024 0.0791849663865776 0.029926487268224375 5.93274848774584e-09 8.226744062702396 0.149158050759852 TT(ph)PLKPSPLPVIPDTIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTPLKPSPLPVIPDTIK 17 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 T(0.143)T(0.856)PLKPS(0.002)PLPVIPDTIK 62.617 0.020349000000000003 3704600.0 37480.0 40005.0 34101.0 45185.0 47029.0 39213.0 42616.0 39387.0 36031.0 32771.0 True False 43824.62373625698 43976.43201616558 34914.09716876269 42653.43094174655 37814.00505050127 37156.601249458734 38579.10396687853 38353.13298397608 36557.88521104497 38712.12288490675 1.1320645955415563 1.135986061702426 0.9018905336853833 1.1018106929593483 0.9768000882546372 0.9598182295485922 0.9965638950252433 0.9907266800635562 0.9443523756042406 1.0 15.240497803468765 -5.238600412617234 24.495153624857814 0.9872002545213098 1.1340253971144572 0.6058269244835252 0.04835164936978638 395.76719944404493 424464.5520899089 0.011778306565515805 0.0311127244841572 5.77297381165646e-06 5.238600412617234 0.14682514259314738 TT(ph)PNSGDVQVTEDAVR ddPTM_PC-9_AZD4547_30min_R2 1 TTPNSGDVQVTEDAVR 16 0 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 T(0.24)T(0.759)PNS(0.001)GDVQVTEDAVR 86.016 0.011218 10016000.0 16490.0 27127.0 26684.0 15560.0 21435.0 26496.0 23962.0 31345.0 31238.0 22342.0 True False 21733.476986692513 35895.27225260235 26330.152724984142 11972.882399603572 18459.120245032434 24839.200931433414 26094.571579455118 26501.35048644384 32889.176906359055 21559.813380375548 1.0080549679745854 1.6649157216395671 1.2212606974117277 0.5553333040675428 0.8561818193581644 1.1521064905897038 1.2103338335575415 1.229201293113522 1.5254852315324707 1.0 14.396057069867513 -9.310123849874763 13.624760824371332 0.9999999981677047 1.1517045069846312 0.024500711164588296 0.29681755617450045 0.0 0.0 0.31012645899255664 0.07521671457206443 4.896391666683267e-10 9.310123849874763 0.15170450881692654 TT(ph)PNSGDVQVTEDAVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTPNSGDVQVTEDAVR 16 0 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 T(0.013)T(0.987)PNSGDVQVTEDAVR 235.4 3.195799999999999e-109 0.0 13850.0 22734.0 16997.0 11045.0 16903.0 11427.0 14151.0 11332.0 6310.3 10025.0 True False 16194.53145003091 24990.881276228185 17402.27294148145 10426.184458373138 13590.978489200765 10827.74800391617 12810.514835632117 11034.547007246474 6402.576199585276 11842.453142143664 1.3674980391013356 2.1102790930447757 1.4694821024498792 0.8804074910180173 1.1476489141286643 0.9143163054100277 1.081745030515968 0.9317788193712923 0.5406461079250944 1.0 13.531680343068443 -5.623941996717994 3.9614625513580415 0.9406612226440516 1.7518725659148977 0.6869692766221345 0.2269576485203193 0.11390693236346806 3.3163062697679115 0.06060894875436375 0.11091687608186618 2.377157752653124e-06 5.623941996717994 0.8112113432708461 TT(ph)PNSGDVQVTEDAVR ddPTM_PC-9_Lapatinib_30min_R1 3 TTPNSGDVQVTEDAVR 16 0 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 T(0.219)T(0.781)PNSGDVQVTEDAVR;T(0.194)T(0.806)PNSGDVQVTEDAVR;T(0.147)T(0.853)PNSGDVQVTEDAVR 237.34 9.9075e-37 24210000.0 45721.3 86942.0 70518.0 66067.0 74993.0 76655.3 84022.0 86679.0 61364.8 67547.0 True False 45069.30587774046 86740.69114070038 64720.28224735194 70925.78757305125 70582.05918191078 73376.931511232 88372.24803719662 90706.42277724663 54453.2500240087 79222.4089492802 0.5688959282542739 1.094900954049927 0.8169441336830238 0.8952743108134894 0.8909355334940503 0.9262143436992608 1.1154955928413428 1.1449591596655275 0.6873465569428819 1.0 16.27362095009697 -6.947062391013611 3.7804061835968588 1.0015528523899264 0.8676506288623363 0.1184699308611945 0.1666336704563706 0.49545075387215637 14.679668880447995 0.06031327480559185 0.051394833674989183 1.129633619151638e-07 6.947062391013611 -0.13390222352759007 TT(ph)PPESAPQNGPSPMAALMSVADTLGTAHS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTPPESAPQNGPSPMAALMSVADTLGTAHSPK 32 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 2 T(0.474)T(0.516)PPES(0.009)APQNGPS(0.001)PMAALMS(0.03)VADT(0.049)LGT(0.172)AHS(0.751)PK 50.828 0.012636 0.0 7028.4 8241.8 6040.1 5749.2 8304.1 4040.7 6609.2 3902.8 4897.0 5522.2 True False 8218.169302772365 9059.991435841352 6184.118891206813 5427.090963157889 6676.971216480629 3828.798578754188 5983.128729535702 3800.355635358413 4968.609360786189 6523.331146288855 1.2598117615794668 1.3888596535522517 0.9480001478577366 0.8319508609102849 1.0235523947422445 0.5869391715507811 0.9171891776396365 0.5825789845913998 0.7616675053531274 1.0 12.671393151107969 -5.411817729264215 2.9279068108601343 0.8017437082991592 1.3295458053334457 0.6535507569054027 0.14535064555952434 0.14986356482345786 2.4347736999544622 0.0392354360799593 0.0956594587010276 3.874202086959524e-06 5.411817729264215 0.5278020970342865 TT(ph)PPPGRPPAPSSEEEDGEAVAH ddPTM_PC-9_AZD4547_30min_R2 1 TTPPPGRPPAPSSEEEDGEAVAH 23 1 Q96KN1 Q96KN1 FAM84B Protein FAM84B 1 T(0.456)T(0.544)PPPGRPPAPSSEEEDGEAVAH 72.676 0.00047162 71374000.0 76418.0 78898.0 76114.0 143900.0 123740.0 92705.0 96462.0 103020.0 95526.0 105560.0 True False 100717.33440685664 104400.23556551835 75104.67862799585 110726.0782328377 106560.83690787575 86908.14169491758 105046.9311283447 87100.62616409153 100575.30933980588 101864.37652996351 0.988739516578993 1.0248944638149227 0.7373007246149857 1.0869951007874425 1.0461050323763654 0.8531750220780417 1.0312430577479168 0.8550646372284112 0.9873452600990646 1.0 16.636290082475398 -3.0434482042692914 1.5866475631194328 0.9526094581884628 12.30644507825866 0.009984259320647615 0.10340706341505176 1799.0990078659188 26.334213339130585 0.027818542523013037 73317.75036113583 0.0009047983412428961 3.0434482042692914 11.353835620070198 TT(ph)PTPSTNSVLSTSTNR ddPTM_PC-9_AZD4547_30min_R2 1 TTPTPSTNSVLSTSTNR 17 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 T(0.148)T(0.758)PTPS(0.011)T(0.002)NS(0.002)VLS(0.006)T(0.031)S(0.031)T(0.011)NR 99.069 0.0066159999999999995 0.0 6047.6 4836.7 10009.0 13096.0 12237.0 11642.0 8589.4 11320.0 8691.2 10772.0 True False 7970.611002105622 6400.068688176418 9876.274120235577 10076.91953118305 10538.10377599542 10914.023899597976 9353.83996012737 9570.754107721932 9150.599088563533 10394.875558741627 0.7667827245322522 0.615694594130494 0.9501098944787338 0.9694122333873261 1.0137787332271953 1.049942718209817 0.8998510763566773 0.9207184880316681 0.8802990508980444 1.0 13.343584866763438 -5.273279527930939 24.348621015371528 0.9609300124550837 0.6912386677587097 0.7647155284509395 0.059744879987638215 212.32611541145346 436637.75300314935 0.01622529709881499 0.03423715245007648 5.329917319453687e-06 5.273279527930939 -0.269691344696374 TT(ph)PTQPSEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTPTQPSEQK 10 0 O95104-2;O95104-3;O95104 O95104-2 SCAF4 Splicing factor, arginine/serine-rich 15 1 T(0.127)T(0.871)PT(0.002)QPSEQK 92.866 0.017504 10803000.0 42229.0 54422.0 41414.0 44003.0 54531.0 48330.0 52238.0 43243.0 41223.0 35728.0 True False 49377.535639231486 59824.65649753191 42401.46682346964 41537.65456965084 43846.0420040589 45795.48971989753 47289.63846963114 42107.9170697458 41825.80838874597 42205.2035773076 1.1699395205803538 1.417471103721858 1.0046502144173417 0.9841832534598725 1.0388776332696932 1.0850673812297476 1.1204693843736673 0.9976949167563285 0.9910107011362548 1.0 15.36513326266127 -5.274935557346509 24.904658595943296 1.0318625981230436 1.2937053128406757 0.7009271596247935 0.06944958612633056 338.3124359549631 624292.1232274337 0.017850936994089583 0.03750354676997251 5.3096322520121435e-06 5.274935557346509 0.2618427147176321 TT(ph)RTPDTSTYCYETAEK ddPTM_PC-9_AZD4547_30min_R2 1 TTRTPDTSTYCYETAEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.302)T(0.348)RT(0.348)PDT(0.001)STYCYETAEK 67.866 0.01312 4293200.0 12130.0 10343.0 15425.0 23219.0 18045.0 17225.0 9223.2 12293.0 10157.0 12285.0 True False 15987.087680326273 13686.17248161116 15220.454421484046 17866.218279973997 15539.763229372995 16147.91802702072 10044.046932294075 10393.39931503761 10693.878284073524 11854.905889262973 1.3485630193661706 1.1544733133652938 1.283895002091013 1.5070738179503802 1.3108297420941493 1.3621295839763639 0.8472481372788461 0.8767171508675532 0.9020635325126456 1.0 13.533196589511292 -7.260452737590586 24.999341890224027 0.8962336197071663 1.32532570610114 0.8423846801013817 0.08923339707397139 35.06347256277734 888447.5096737798 0.03760637377851266 0.02744074858548727 5.4896829422597046e-08 7.260452737590586 0.4290920863939738 TT(ph)RTPEEGGYSYDISEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTRTPEEGGYSYDISEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.305)T(0.391)RT(0.305)PEEGGYSYDISEK 87.088 0.030443 22127000.0 63513.0 41725.0 53873.0 83944.0 85789.0 78578.0 73823.0 78916.0 70767.0 54758.0 True False 74264.49646106969 45867.1822490816 55157.53663449027 79240.88983012002 68979.26129148938 74457.23135133686 66829.9510077641 76844.53861841375 71801.8334969891 64685.19193591052 1.148091150980123 0.7090831900835414 0.8527073196155905 1.225023648513421 1.0663841170917971 1.1510707338568058 1.0331568788414291 1.1879772838047784 1.1100196404786071 1.0 15.981147860457131 -5.749084853578213 24.99907511142178 1.1149785822713463 0.8838727436174488 0.38440942698117886 0.11932155992096634 202.00032040368367 408739.0996594396 0.030721938455256736 0.05272551675741503 1.7820305556967014e-06 5.749084853578213 -0.23110583865389744 TT(ph)SGDDACNLTSFR ddPTM_PC-9_AZD4547_30min_R2 1 TTSGDDACNLTSFR 14 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GUE9;Q96N67-7;A0A0U1RQT6 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 T(0.351)T(0.587)S(0.062)GDDACNLTSFR 178.67 0.00017274 17236000.0 25232.0 41494.0 33842.0 29987.0 28267.0 34201.0 33325.0 38174.0 32762.0 21859.0 True False 33255.25114179658 54906.124040604656 33393.232968030024 23073.960444531636 24342.614973936612 32062.406063404083 36290.860440920726 32275.08545125241 34493.73243505139 21093.723063361784 1.5765472525596231 2.6029603155249763 1.5830886215639934 1.0938780401743955 1.154021739112424 1.5199974877405156 1.7204578031061397 1.5300800790028297 1.6352605147720185 1.0 14.364526134283045 -5.503238823077373 23.31191797785933 1.4062542343654554 2.0905718513708864 0.4310953145547589 0.3213166622284664 281.7096251161979 334377.7724779597 0.08327241508218938 0.16899664704715836 3.1387821700628327e-06 5.503238823077373 0.684317617005431 TT(ph)SGDDACNLTSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTSGDDACNLTSFR 14 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GUE9;Q96N67-7;A0A0U1RQT6 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 T(0.016)T(0.492)S(0.492)GDDACNLTSFR 106.55 0.0021156999999999994 2850200.0 13574.0 23083.0 13947.0 13598.0 13306.0 9616.8 10754.0 9328.9 8747.2 9953.4 True False 15871.810101279407 25374.52768976753 14279.54937429204 12836.148145310808 10698.784817920214 9112.478078591146 9735.303267782328 9084.026259786593 8875.111251923416 11757.872628928952 1.3498879093339184 2.158088328609403 1.2144670915348055 1.0917066845688461 0.909925218240333 0.7750107835129032 0.8279816915034176 0.7725909734245927 0.7548228775745691 1.0 13.521339434168409 -5.63401590889278 2.0323343348139185 0.8383023557579768 1.7538310479802375 0.7216349547258096 0.2139970911172969 0.1498890575192309 1.244516201315912 0.059623888804531996 0.13396701049400028 2.3226517123982033e-06 5.63401590889278 0.9155286922222606 TT(ph)SPLEEEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTSPLEEEER 10 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 T(0.003)T(0.943)S(0.054)PLEEEER;T(0.02)T(0.801)S(0.179)PLEEEER 131.42 0.00044121 49134000.0 147422.0 200631.0 194550.0 180339.0 186955.0 176744.0 175611.0 136484.0 153661.0 137403.0 True False 172377.63288277644 220548.31975591302 199188.809834984 170235.19049692657 150322.50981769664 167475.2334999701 158975.85476646086 132901.43961675154 155908.00142694876 162313.07621845038 1.0620070600521463 1.358783438119836 1.227188926953144 1.0488076158929682 0.9261269228573048 1.0318037055410878 0.9794396019732995 0.8187968752307119 0.9605387628604777 1.0 17.308419704979464 -5.902346838366846 3.0726442528063247 0.9501430475943923 1.2321025417448526 0.6517487515509983 0.08567087568688232 0.14553912436850477 2.7539788426755263 0.025326613077901877 0.0400130778916841 1.252140784775963e-06 5.902346838366846 0.2819594941504603 TT(ph)SPPEVSGYSYEK ddPTM_PC-9_AZD4547_30min_R2 1 TTSPPEVSGYSYEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.025)T(0.853)S(0.122)PPEVSGYSYEK 108.58 0.0016428 12463000.0 20488.0 23410.0 24419.0 34442.0 31359.0 23594.0 21245.0 21834.0 23624.0 23040.0 True False 27002.757823126507 30976.82469249903 24095.18810490885 26501.929023595523 27005.344145741634 22118.663450190234 23135.76384298157 18460.056995406438 24872.716410648136 22233.37661283019 1.214514479440071 1.3932577688007708 1.0837394843122599 1.1919884903268396 1.2146308055681334 0.9948404974809917 1.040587052783995 0.8302858048450326 1.1187107043513518 1.0 14.44043944859144 -6.761806986216339 6.031530108893573 0.9879529407559033 1.221107048360617 0.5675225600949263 0.0970941261435647 0.11387491008506333 15.518481353447076 0.0332411734358903 0.03115652507483296 1.7305853135038117e-07 6.761806986216339 0.23315410760471367 TT(ph)SPPEVSGYSYEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TTSPPEVSGYSYEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.025)T(0.957)S(0.018)PPEVSGYSYEK;T(0.178)T(0.72)S(0.099)PPEVS(0.003)GYSYEK;T(0.088)T(0.456)S(0.456)PPEVSGYSYEK 161.21 0.00037511 521240000.0 142136.0 147502.0 148829.0 182813.0 179965.0 150742.0 164045.0 145356.0 149000.0 112923.0 True False 166196.81748603552 162145.02375324184 152377.6477971257 172570.58029774256 144702.1501395618 142836.82415387523 148505.47001704964 141540.55901741268 151178.84311969418 133395.0460020239 1.2458994727848733 1.2155250784259388 1.142303648928715 1.293680578626018 1.084764048414259 1.0707805757022497 1.1132757509960038 1.061063084870972 1.133316773378529 1.0 17.025345563440382 -6.286155559328371 23.23938405778595 1.0817359600271197 1.2178610599387372 0.6906955322782462 0.048105921270151834 184.06540673742336 173066.80293214682 0.014142449488399643 0.016046791309499157 5.174214642892275e-07 6.286155559328371 0.13612509991161748 TT(ph)SPPEVSGYSYEK ddPTM_PC-9_Lapatinib_30min_R1 1 TTSPPEVSGYSYEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.223)T(0.687)S(0.09)PPEVSGYSYEK 83.869 0.018484 13315000.0 75739.0 70292.0 65447.0 62193.0 71716.0 69308.0 60803.0 54120.0 71441.0 53598.0 True False 74658.94797116844 70129.2431927275 60066.20029272585 66766.88068976605 67497.80587908093 66343.85840483918 63951.08182863611 56634.61277477355 63394.562272918774 62862.34288515419 1.1876577382355276 1.115600214278515 0.955519593064854 1.0621125084654452 1.0737399018422755 1.0553831651811882 1.0173194140325152 0.900930671296195 1.008466426215404 1.0 15.939908422061627 -1.5228787452803376 0.6301069345659456 1.0016806706552277 15.722774734336605 0.5451373111859243 0.05176658466001565 166.42792526829095 1.157103923142331 0.024378562952174745 3401.2508944452893 0.029999999999999995 1.5228787452803376 14.721094063681377 TT(ph)SRSPVLSR ddPTM_PC-9_AZD4547_30min_R2 2 TTSRSPVLSR 10 1 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;H7C3Z6;O95819-6;E7EN19 C9J840;O95819-6;E7EN19 MAP4K4 1 T(0.04)T(0.916)S(0.04)RS(0.005)PVLSR;T(0.014)T(0.742)S(0.238)RS(0.006)PVLSR 76.165 0.016947 29985100.0 26243.6 20858.8 21660.8 47731.0 30398.4 33408.2 25317.8 35756.2 24767.5 31836.9 True False 34588.51889920945 27600.999183934167 21373.56363908471 36727.35538659882 26178.106874578672 31319.179972732287 27571.035152922508 30230.900885735595 26076.659486146593 30722.299821398155 1.125844064418591 0.8984027675138436 0.6957019416950672 1.1954624360842325 0.852088125783655 1.0194282379510664 0.8974274488955809 0.9840051383353696 0.8487860491480569 1.0 14.906998597455365 -10.487780001122704 5.56504235140914 1.0000000973387788 0.9439398448800385 0.01339139487471297 0.136750339054914 1.5661172114490277e-07 2.9245839397451577e-08 0.12554298318656493 0.030448592810870114 3.252520173185654e-11 10.487780001122704 -0.056060252458740356 TT(ph)SSMDPNDMMR ddPTM_PC-9_Lapatinib_30min_R1 2 TTSSMDPNDMMR 12 0 B4DIB3;A0A087X0I6;Q9P0L2-2;Q9P0L2-3;Q9P0L2 B4DIB3 MARK1 Serine/threonine-protein kinase MARK1 1 T(0.191)T(0.809)SSMDPNDMMR;T(0.203)T(0.791)S(0.006)SMDPNDMMR 100.69 0.011290000000000001 995930.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TT(ph)SSSDLTTSSSSSGPR ddPTM_PC-9_AZD4547_30min_R2 2 TTSSSDLTTSSSSSGPR 17 0 Q5QP82;A0A0A0MQT4 Q5QP82 DCAF10 DDB1- and CUL4-associated factor 10 1 T(0.055)T(0.467)S(0.467)S(0.011)SDLTTSSSSSGPR;T(0.021)T(0.575)S(0.393)S(0.01)S(0.001)DLTTSSSSSGPR 167.92 2.6490999999999998e-24 0.0 23828.0 22188.0 35746.0 49012.0 39797.0 39371.0 29397.0 43435.0 29957.0 34600.0 True False 31404.808346810743 29359.837090011453 35271.984683978495 37713.04062785154 34271.87349622369 36909.12514611509 32013.276050464992 36723.11878700552 31540.465861572364 33388.66453142035 0.9405829429702796 0.8793354721445186 1.0564059742726712 1.129516294141137 1.026452359721432 1.1054387967923012 0.9588067237711455 1.0998678534281385 0.9446459241246759 1.0 15.027070769673214 -5.26667521573379 24.66659516614488 1.0458387114273386 0.9099592026555388 0.42895705356213987 0.05979307513838707 272.1627730191634 1282196.4251377678 0.014809160451718754 0.03237131494902205 5.411588737537975e-06 5.26667521573379 -0.13587950877179988 TT(ph)SSSDLTTSSSSSGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTSSSDLTTSSSSSGPR 17 0 Q5QP82;A0A0A0MQT4 Q5QP82 DCAF10 DDB1- and CUL4-associated factor 10 1 T(0.016)T(0.573)S(0.399)S(0.012)S(0.001)DLTTSSSSSGPR 122.12 0.00015317 3554400.0 10894.0 12953.0 13852.0 15692.0 19271.0 18018.0 20280.0 13969.0 14427.0 16203.0 True False 12738.139033692196 14238.88823660525 14182.284214002537 14812.828114150421 15494.985888031011 17073.10436112381 18358.931585514758 13602.328551378932 14637.967581797491 19140.475637122574 0.6655079672621524 0.7439150680764279 0.7409577736143754 0.7739007324050629 0.8095402738048365 0.891989555787781 0.9591679921426808 0.7106578127555767 0.7647650904456859 1.0 14.224339060511944 -5.949089870715862 1.282616268691287 0.8516595964172733 0.7041125372705935 0.3851950500167107 0.0815409815694999 0.5663428898396196 1.890101835046939 0.030952375753899933 0.061533233230721046 1.124372277946959e-06 5.949089870715862 -0.14754705914667976 TTAGS(ph)VDWTDQLGLR ddPTM_PC-9_AZD4547_30min_R2 2 TTAGSVDWTDQLGLR 15 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 T(0.135)T(0.006)AGS(0.859)VDWT(0.001)DQLGLR;T(0.013)T(0.013)AGS(0.952)VDWT(0.022)DQLGLR 189.8 1.8417000000000001e-07 19845800.0 13304.3 19684.3 25630.2 35208.1 41555.0 33030.7 27931.7 41151.0 28083.6 28520.6 True False 17534.79065336889 26046.86502753345 25290.326801524825 27091.41650472251 35785.80554151258 30965.285107408596 30417.56718912725 34792.058505906825 29568.041762194287 27522.102474995 0.637116683556425 0.9463980831841656 0.9189096953803643 0.9843512692875195 1.3002569688862071 1.1251060901158214 1.1052050698802136 1.2641497333830831 1.0743380448153665 1.0 14.748303064501826 -4.456966850489707 0.6971497937296445 1.1520230365212747 0.14251657826181913 0.6832276495504557 0.1008214016007448 2.5229761025680304 0.6776784472851833 0.042049904978121944 2.2271403719135874 3.491669662252294e-05 4.456966850489707 -1.0095064582594555 TTAGS(ph)VDWTDQLGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TTAGSVDWTDQLGLR 15 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 T(0.002)T(0.005)AGS(0.993)VDWTDQLGLR;T(0.445)T(0.015)AGS(0.53)VDWT(0.01)DQLGLR;T(0.254)T(0.005)AGS(0.742)VDWTDQLGLR;T(0.001)T(0.003)AGS(0.996)VDWT(0.001)DQLGLR;TTAGS(0.998)VDWT(0.002)DQLGLR 142.57 1.3517000000000001e-05 28530700.0 43724.8 55102.0 67886.9 72688.0 94226.0 79388.8 75069.1 75840.7 74621.8 64545.6 True False 51126.54503583482 60572.162403568414 69505.5811585019 68615.52701767575 75763.09170700077 75225.51157200497 67958.01139478145 73849.96198486397 75713.002654424 76247.20633731144 0.6705366332984731 0.7944181211781334 0.9115820040804493 0.8999087352017363 0.9936507230419829 0.9866002334461071 0.8912852635431748 0.9685595778835194 0.9929937933656983 1.0 16.21839685839572 -4.5442662821199535 0.8430731080658476 0.9676412820927608 0.3821561618469138 0.8931911708055036 0.033076252653827236 1.0311158502766726 0.4328671903174371 0.012306292535609907 0.6167986220141061 2.855838985223953e-05 4.5442662821199535 -0.585485120245847 TTAGS(ph)VDWTDQLGLR ddPTM_PC-9_Lapatinib_30min_R1 4 TTAGSVDWTDQLGLR 15 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 TTAGS(0.928)VDWT(0.072)DQLGLR;TTAGS(0.984)VDWT(0.015)DQLGLR;TTAGS(1)VDWTDQLGLR;TT(0.006)AGS(0.994)VDWTDQLGLR 182.57 4.4576e-06 32017900.0 130745.0 120798.0 131514.0 112579.0 108239.0 110034.0 97830.0 91240.6 110495.0 109947.0 True False 128880.55232430366 120518.2996528069 120701.42657872074 120858.43521253455 101872.59482606166 105328.1023217821 102895.1587141337 95479.9713661862 98049.88953606688 128951.19245483153 0.9994521948251652 0.9346039951900525 0.9360241210720057 0.9372417029401905 0.7900089397137228 0.8168059582595638 0.7979387918430872 0.7404349626284419 0.7603643492510656 1.0 16.97646558870948 -6.225724540933848 5.513418086914593 0.8034255673016957 0.950824326919444 0.46809926128434176 0.06915957372681637 0.1576292258612691 13.488184171334149 0.01979048465781988 0.025183927839590982 5.946692186443524e-07 6.225724540933848 0.1473987596177483 TTAGSVDWT(ph)DQLGLR ddPTM_PC-9_AZD4547_30min_R2 1 TTAGSVDWTDQLGLR 15 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 T(0.015)T(0.015)AGS(0.246)VDWT(0.723)DQLGLR 128.35 4.4541000000000006e-05 11009000.0 12560.0 11999.0 23384.0 31737.0 33100.0 25866.0 26485.0 33346.0 27614.0 30348.0 True False 16553.81873577065 15877.442096766157 23073.912881165834 24420.524981762108 28504.636347589145 24248.594931025695 28842.113691756495 28193.14191484943 29073.619664901667 29285.525757212286 0.5652559859436316 0.5421600495888637 0.7878947802561923 0.8338769528748498 0.9733353119183518 0.828006132860834 0.9848590027328913 0.9626988481812102 0.9927641356324828 1.0 14.83790017464616 -5.4433012507461305 0.977666155426253 0.9608104911116666 0.47417737410254923 0.8952356958615678 0.053120033178959206 0.24928286853475665 0.3659344989823311 0.01929654579791436 0.10286824410478806 3.6032861239849643e-06 5.4433012507461305 -0.4866331170091174 TTAPT(ph)EGKSPLK ddPTM_PC-9_Lapatinib_30min_R1 1 TTAPTEGKSPLK 12 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 TTAPT(0.83)EGKS(0.17)PLK 65.219 0.030382 16988000.0 67838.0 80231.0 83342.0 82531.0 87359.0 72752.0 79970.0 81812.0 75971.0 68297.0 True False 66870.61768003448 80045.23004887794 76489.94246942355 88600.60505534522 82220.71537440216 69640.56655319528 84110.45530378484 85613.28418938955 67414.34596990394 80102.04544996776 0.8348178539560802 0.9992907122312463 0.9549062329151089 1.106096661547622 1.026449635743169 0.8693981054041026 1.0500412920956026 1.0688027216841067 0.8416057990930003 1.0 16.28955146266842 -4.760402595213222 24.886122129459725 0.99454588826651 0.8348176595417949 0.2574310819237968 0.07920318448608248 33.71348403506253 808820.0829834844 0.019348509148694324 0.11487585839495187 1.736190616917404e-05 4.760402595213222 -0.15972822872471515 TTAPTEGKS(ph)PLKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTAPTEGKSPLKK 13 2 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 T(0.018)T(0.005)APT(0.048)EGKS(0.929)PLKK 44.614 0.044442 112170000.0 169240.0 295060.0 199920.0 206060.0 218780.0 156020.0 217910.0 181760.0 136380.0 127010.0 True False 197888.98935763378 324351.60681639303 204686.85100082235 194515.12625553407 175911.62952537098 147838.03654248716 197267.9872682209 176988.9925906385 138374.29949438834 150035.90758939311 1.3189441950069802 2.161826538911298 1.3642524265657379 1.296457157361745 1.1724635279095494 0.9853510330812213 1.3148051718931775 1.1796442294001281 0.922274552256388 1.0 17.194948291835637 -5.605371316562777 2.6448286488343076 1.1284220618668803 1.7448597111600828 0.5266280071559784 0.22838037089156707 0.19294536658585346 2.7106849297490005 0.061436738110322596 0.12678495002198453 2.4810109636643314e-06 5.605371316562777 0.6164376492932024 TTAS(ph)SPPHLPSK ddPTM_PC-9_Lapatinib_30min_R1 1 TTASSPPHLPSK 12 0 Q4G0A6 Q4G0A6 FAM188B Protein FAM188B 1 T(0.041)T(0.041)AS(0.459)S(0.459)PPHLPSK 70.27199999999999 0.017095 13462000.0 62534.0 67360.0 66133.0 60593.0 75943.0 82213.0 70523.0 82769.0 86896.0 55411.0 True False 61642.25369266889 67204.03205858616 60695.80002076233 65049.2113523225 71476.18204968264 78696.9416378635 74174.33586831088 86614.74990308982 77108.85742455372 64988.717519483536 0.9485070031454094 1.0340876789642521 0.9339436495660314 1.000930835922725 1.099824473813538 1.210932368595676 1.1413417389883638 1.3327659509071375 1.1864960622039753 1.0 15.987901657820967 -6.435821627560027 2.3033370339636385 1.1936885763049832 0.9768159847862088 0.5538379731344498 0.08156826990781525 0.20799181238476044 2.1775104413651807 0.027448283638754862 0.031217243848782814 3.665881079647195e-07 6.435821627560027 -0.21687259151877436 TTAS(ph)SPPHLPSKR ddPTM_PC-9_AZD4547_30min_R2 3 TTASSPPHLPSKR 13 1 Q4G0A6 Q4G0A6 FAM188B Protein FAM188B 1 T(0.007)T(0.007)AS(0.493)S(0.493)PPHLPSKR;T(0.009)T(0.007)AS(0.555)S(0.429)PPHLPSKR;T(0.129)T(0.129)AS(0.371)S(0.371)PPHLPSKR 72.66199999999999 0.010578 21452300.0 60533.0 57749.0 127529.0 162315.0 140697.0 119132.0 86032.0 135369.0 103396.0 120847.0 True False 79781.23483538248 76415.23490675476 125837.88213403174 124895.78449175159 121163.65015700151 111682.65720725861 93688.68133393221 114450.8315201598 108861.30147288243 116616.18331296428 0.684135190921766 0.6552712731274892 1.0790773506651223 1.0709987322820131 1.0389951610046535 0.9576943271032503 0.8033934799812369 0.9814318070503706 0.9335008090663542 1.0 16.831408485661868 -5.251750817812827 24.980642743039944 0.9802781611909507 0.6697031820459735 0.7364332898402041 0.07498825792624766 367.2539275058832 946909.6812074211 0.02145312745825846 0.055232999817442154 5.60078861956861e-06 5.251750817812827 -0.3105749791449772 TTAS(ph)SPPHLPSKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTASSPPHLPSKR 13 1 Q4G0A6 Q4G0A6 FAM188B Protein FAM188B 1 T(0.11)T(0.11)AS(0.39)S(0.39)PPHLPSKR 49.188 0.04105 2520900.0 13475.0 14853.0 18381.0 23793.0 31361.0 32895.0 27541.0 27419.0 27158.0 20211.0 True False 15756.051356618538 16327.507679942688 18819.272750330696 22459.955347946783 25216.03717682219 31169.928291662094 24932.11710042712 26699.28030283191 27555.134372111766 23875.094309812026 0.6599367169889344 0.6838719658264352 0.7882386769293924 0.9407273980365531 1.0561649244023747 1.3055415776452906 1.0442730310045596 1.1182900455333162 1.1541371947916177 1.0 14.543218811547234 -5.864680279337436 1.5286320662494997 1.1291357454753528 0.6681381520497095 0.8476585510314832 0.0774708733506686 0.13994709810063546 0.6652029282231018 0.02582462237860304 0.051662384294428654 1.3655880907740177e-06 5.864680279337436 -0.4609975934256433 TTASS(ph)PPHLPSK ddPTM_PC-9_AZD4547_30min_R2 2 TTASSPPHLPSK 12 0 Q4G0A6 Q4G0A6 FAM188B Protein FAM188B 1 T(0.006)T(0.001)AS(0.105)S(0.888)PPHLPSK;T(0.008)T(0.001)AS(0.094)S(0.897)PPHLPSK 138.63 6.9981e-05 17598700.0 58406.0 46831.0 87698.0 124134.0 105731.0 93234.0 71103.0 108383.0 81566.0 102912.0 True False 76977.89307973091 61968.20491988129 86535.06721914472 95516.82415118175 91052.07569990786 87404.0632412916 77431.02925523736 91634.89774357103 85877.41223971067 99309.08220397476 0.7751344728131013 0.623993330162919 0.8713711304008127 0.9618135827194139 0.9168554746371785 0.880121548820369 0.7796973603703111 0.9227242434418895 0.8647488259263512 1.0 16.59963804344069 -5.355671602806638 6.17762875099494 0.8960893479767473 0.7007830969000143 0.6008290323856291 0.06536553625243932 0.14274548411721127 7.641503507164845 0.01691377569920272 0.03582518603247321 4.408881205479639e-06 5.355671602806638 -0.19530625107673305 TTASS(ph)PPHLPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTASSPPHLPSK 12 0 Q4G0A6 Q4G0A6 FAM188B Protein FAM188B 1 T(0.001)T(0.001)AS(0.042)S(0.955)PPHLPS(0.001)K 96.135 0.013388999999999998 0.0 12411.0 20318.0 29287.0 26645.0 28128.0 28216.0 25246.0 24612.0 25395.0 22127.0 True False 14511.937171576448 22335.03676301593 29985.313151566024 25152.16703425553 22616.520318537503 26736.303288570834 22854.516114788235 23965.961078569566 25766.35383238008 26138.44994276439 0.5551950174303899 0.8544897196246591 1.1471725835780295 0.9622669702806198 0.8652586656079879 1.0228725631059061 0.8743638649129151 0.9168853214726985 0.9857644155946855 1.0 14.673885968800901 -4.822501202993725 3.639482758458591 0.9649597148625384 0.5273427760617132 0.7234636555984271 0.07749008284034685 0.129969100568293 2.917290067153672 0.019833659913368374 0.14365490310499748 1.5048693503155356e-05 4.822501202993725 -0.4376169388008252 TTCMSSQGS(ph)DDEQIKR ddPTM_PC-9_Lapatinib_30min_R1 1 TTCMSSQGSDDEQIKR 16 1 E7EW69;E7EX04;B5ME97;Q9P0V9;Q9P0V9-2;C9JEW2;C9JNR7 E7EW69 SEPT10 Septin-10 1 T(0.006)T(0.006)CMS(0.01)S(0.029)QGS(0.949)DDEQIKR 58.29 0.02481 6413500.0 19712.0 18594.0 22923.0 16370.0 20142.0 17683.0 16673.0 15526.0 14216.0 14512.0 True False 19430.90326526193 18550.946735411955 21038.35942533888 17573.90440871916 18957.287160695632 16926.739311086316 17536.246358384444 16247.39464044964 12614.844378883452 17020.379863975486 1.1416257110917039 1.0899255412434121 1.2360687360372993 1.0325212803220238 1.1137992989698022 0.9944983276732051 1.030308753302317 0.9545847255053391 0.7411611538461267 1.0 14.054975615266516 -7.227755002772551 0.9151447821346524 0.8824734421580327 1.1346178251981927 0.577739039931237 0.08134420626479781 0.4073805853497831 0.6690769119882515 0.05965271758942978 0.03549080998660779 5.91895444190794e-08 7.227755002772551 0.25214438304015996 TTDEELS(ph)ELEDR ddPTM_PC-9_AZD4547_30min_R2 1 TTDEELSELEDR 12 0 Q9BV36;Q9BV36-4;H7C052;H7C3K9;Q9BV36-5;H7C190;Q9BV36-2;H7C2D8 Q9BV36;Q9BV36-2 MLPH Melanophilin 1 TTDEELS(1)ELEDR 112.5 0.0019222999999999998 0.0 10824.0 8385.5 9994.3 14426.0 11200.0 8920.3 10450.0 9561.0 7181.1 12858.0 True False 14265.806846813803 11095.948887610019 9861.769051840387 11100.308579478216 9645.07332607246 8362.512230852413 11380.02975566756 8083.567139923092 7560.678285493791 12407.84533367061 1.14974086661939 0.8942687943973192 0.7948010945203314 0.8946201601462431 0.7773366822923766 0.6739697349514376 0.9171640562593157 0.6514883867859862 0.6093465933989941 1.0 13.59896498765947 -1.5228787557131436 0.7597528047422669 0.7648352262825484 72.64948661712775 0.4631442520807323 0.11713113706355897 339.81072783599086 1.4092224277311696 0.04240753906405472 41856.842313551475 0.0299999992793273 1.5228787557131436 71.8846513908452 TTDEELS(ph)ELEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTDEELSELEDR 12 0 Q9BV36;Q9BV36-4;H7C052;H7C3K9;Q9BV36-5;H7C190;Q9BV36-2;H7C2D8 Q9BV36;Q9BV36-2 MLPH Melanophilin 1 TTDEELS(1)ELEDR 103.97 0.0045723 0.0 12695.0 12594.0 15794.0 15234.0 13125.0 9057.5 16798.0 10978.0 14236.0 10703.0 True False 14844.012762320754 13844.249089153587 16170.588859078553 14380.488369294379 10553.250468600852 8582.508755182529 15206.771833011682 10689.839132152478 14444.174568133998 12643.369175098616 1.1740551554530538 1.0949810052545275 1.2789778290209914 1.1373936938911073 0.834686571470657 0.6788150085885305 1.202746801300538 0.8454897570503868 1.1424308163509223 1.0 13.626093340257206 -6.1297599232512106 6.006784018259369 0.942728568121812 1.1788694910542294 0.34959480326208314 0.14796156802347413 0.2637958148451472 11.778291323756843 0.043866247625397606 0.05709377099133617 7.417201487717395e-07 6.1297599232512106 0.2361409229324174 TTDEELS(ph)ELEDR ddPTM_PC-9_Lapatinib_30min_R1 1 TTDEELSELEDR 12 0 Q9BV36;Q9BV36-4;H7C052;H7C3K9;Q9BV36-5;H7C190;Q9BV36-2;H7C2D8 Q9BV36;Q9BV36-2 MLPH Melanophilin 1 TTDEELS(1)ELEDR 72.49600000000001 0.024891999999999997 3167200.0 12023.0 6461.9 10191.0 10576.0 8693.5 8019.5 8920.3 8050.8 9456.6 8893.9 True False 11851.549815251832 6446.937867567953 9353.135318397612 11353.794320501767 8182.165422078616 7676.524679367562 9382.149486636883 8424.869558890367 8391.498125587312 10431.198764623176 1.1361637413569088 0.6180438138550652 0.8966500906988988 1.0884457842954276 0.7843935876121899 0.7359197013292532 0.8994315704591802 0.8076607251951557 0.8044615307347613 1.0 13.34861734300617 TTDGSLQNT(ph)SSEGSR ddPTM_PC-9_Lapatinib_30min_R1 2 TTDGSLQNTSSEGSR 15 0 G3V0J0;Q06787-2;Q06787-7;A8MQB8;Q06787-6;Q06787-4 G3V0J0 FMR1 Fragile X mental retardation protein 1 1 TTDGS(0.006)LQNT(0.609)S(0.344)S(0.041)EGS(0.001)R;TTDGS(0.008)LQNT(0.889)S(0.091)S(0.011)EGSR 91.59200000000001 0.012759 2249200.0 24088.0 23724.0 31595.0 24155.7 30113.0 27198.0 25200.0 23361.0 30853.0 21644.0 True False 23744.500702801797 23669.068535598206 28997.38106022693 25932.190759052995 28341.812544435874 26034.804941634662 26504.732695453014 24446.437343523372 27378.010243506702 25385.136561182848 0.9353702173542846 0.9323987081397572 1.14229761933082 1.0215501774651339 1.1164727231672318 1.0255924713615778 1.0441043967430206 0.9630216991192055 1.0785055332485867 1.0 14.631696400720445 -5.221179744194227 24.475232638191365 1.0480491199441795 0.9338843194456838 0.45604520527918757 0.05025635824090975 353.2044580573752 214723.80471332435 0.012427393245749431 0.032878881912378075 6.00924977401343e-06 5.221179744194227 -0.11416480049849564 TTDGYLLR ddPTM_PC-9_Lapatinib_30min_R1 2 TTDGYLLR 8 0 D6RAT0;P61247;D6RG13;D6R9B6;D6RB09;H0Y9Y4;E9PFI5;D6RAS7;H0Y8L7;D6RED7 D6RAT0 RPS3A 40S ribosomal protein S3a 0 ; 104.37 0.017781 12119400.0 50410.0 50541.0 64756.0 52863.0 49452.0 52737.0 49582.0 48600.0 51119.0 51491.0 False True 49691.14415593818 50423.97541972976 59432.01164538869 56750.72136579843 46543.33058637277 50481.56144595141 52149.11335341076 50858.1334230228 45361.439913065806 60391.150742555255 0.8228216145072195 0.8349563603231355 0.9841178867206003 0.9397191586516407 0.7706978591082804 0.8359099110588574 0.8635224318827781 0.8421454600166294 0.7511272654240283 1.0 15.882049543087245 -6.247077917581583 24.75313071183484 0.836589325060594 0.8974228030423913 0.09434326224565148 0.07607735553502624 1551.106303975504 2673454.5079397745 0.022410970854028087 0.02879391172653701 5.661377081058471e-07 6.247077917581583 0.06083347798179728 TTEEQVQAS(ph)TPCPR ddPTM_PC-9_Lapatinib_30min_R1 1 TTEEQVQASTPCPR 14 0 Q14137 Q14137 BOP1 Ribosome biogenesis protein BOP1 1 TTEEQVQAS(0.5)T(0.5)PCPR 184.51 6.5202e-06 11907000.0 12809.0 13987.0 17554.0 15975.0 14477.0 13881.0 11815.0 10784.0 15370.0 11111.0 True False 12626.341311117081 13954.613960858722 16110.777880399542 17149.854791037782 13625.491322877107 13287.341988191436 12426.722888761009 11285.064008927531 13638.86874672472 13031.52154552312 0.9689076802742781 1.0708353519664573 1.2362929243618739 1.3160285797117441 1.0455794647830698 1.0196308958838503 0.9535895593887972 0.8659820704363129 1.046606008291507 1.0 13.669717920709948 -6.652847842992004 2.9043507338615115 0.9637858582591606 1.150498920950927 0.39170125752953167 0.0983591373194552 0.2745013953141739 4.668144260401978 0.03789116220341438 0.03743364042712897 2.2240889736536453e-07 6.652847842992004 0.18671306269176646 TTEEQVQAST(ph)PCPR ddPTM_PC-9_AZD4547_30min_R2 3 TTEEQVQASTPCPR 14 0 Q14137 Q14137 BOP1 Ribosome biogenesis protein BOP1 1 TTEEQVQAS(0.188)T(0.812)PCPR;TTEEQVQAST(1)PCPR;TTEEQVQAS(0.229)T(0.771)PCPR 190.41 5.2505e-06 38224900.0 47892.0 41186.0 50260.0 73063.0 75433.0 64404.0 47621.0 69807.0 54455.0 66596.0 True False 63120.659784516516 54498.56906387293 49593.51956069941 56219.45416209746 64960.4300183593 60376.807698823905 51859.17674589907 59019.93215527777 57333.38012791412 64264.494310244816 0.982201143290628 0.8480354455257102 0.771709481152696 0.8748136084396941 1.0108292411787256 0.9395049061982403 0.806964674701126 0.9183909838355178 0.8921470672612799 1.0 15.971734258154791 -14.522876846043568 0.3202583947062462 2.0289556217006104 0.8868173667678587 0.16777967755676315 0.07022069990044806 634.584423524714 5.619085888468986 442.5888062931335 0.06687491077052657 3.000013119491509e-15 14.522876846043568 -1.1421382549327517 TTEEQVQAST(ph)PCPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TTEEQVQASTPCPR 14 0 Q14137 Q14137 BOP1 Ribosome biogenesis protein BOP1 1 TTEEQVQAS(0.03)T(0.97)PCPR;TTEEQVQAS(0.028)T(0.972)PCPR;TTEEQVQAS(0.052)T(0.948)PCPR;TTEEQVQAS(0.206)T(0.794)PCPR 217.79 3.9171e-15 31994900.0 104516.0 110405.0 118082.0 108277.0 122061.0 105112.0 106768.0 110559.0 100082.0 81417.0 True False 122208.4945149048 121365.27875877441 120897.52270847895 102210.59072877042 98144.02327221993 99599.74168089933 96654.16210661952 107656.9433969433 101545.50991345783 96177.25760338252 1.2706589640855674 1.2618916548781491 1.2570281761103888 1.0627313907230362 1.020449383958815 1.0355851701618537 1.00495859951844 1.1193596706708036 1.0558162339397636 1.0 16.553408169368737 -5.772720103430823 4.882308268674659 1.0433980004776946 1.2655660059752218 0.9115736261456682 0.0315312526523503 0.04998745456363333 3.1315217630178194 0.009210331309712338 0.014921050810977863 1.6876403349816239e-06 5.772720103430823 0.22216800549752724 TTEEQVQAST(ph)PCPR ddPTM_PC-9_Lapatinib_30min_R1 3 TTEEQVQASTPCPR 14 0 Q14137 Q14137 BOP1 Ribosome biogenesis protein BOP1 1 TTEEQVQAS(0.202)T(0.798)PCPR;TTEEQVQAS(0.175)T(0.825)PCPR;TTEEQVQAS(0.072)T(0.928)PCPR 133.23 0.00012983 15065200.0 58350.0 61854.0 73258.0 66097.0 68167.0 61874.0 60406.0 49523.0 67896.0 50328.0 True False 57517.91829992049 61710.78086329841 67235.01002405769 70957.99387312813 64157.551081478356 59227.79325533873 63533.52711117201 51824.019372599934 60248.83750342372 59027.1277421553 0.9744319349430757 1.0454647417856067 1.139052713487202 1.2021251344481765 1.0869163643153021 1.0033995473074682 1.0763445476917282 0.8779695261300825 1.0206974285891928 1.0 15.849090521555741 -7.214030424666691 1.571968299343748 0.9707321832776197 1.0929866004243065 0.28992985205132893 0.07221496072540896 0.4903964604522523 2.3753718003894404 0.04227611879808242 0.026474601784824425 6.108992266265685e-08 7.214030424666691 0.12225441714668683 TTEINRLPSANQGS(ph)PFK ddPTM_PC-9_Lapatinib_30min_R1 1 TTEINRLPSANQGSPFK 17 1 Q56NI9;E5RFP7;E5RIE3;E5RFE4 Q56NI9 ESCO2 N-acetyltransferase ESCO2 1 TTEINRLPS(0.002)ANQGS(0.998)PFK 72.793 0.0054429 9051500.0 51276.0 30397.0 20803.0 22143.0 20307.0 25375.0 14328.0 13442.0 19117.0 18304.0 True False 50544.79483713325 30326.6176140861 19092.65764190223 23771.470086882615 19112.5821850981 24289.770402014095 15069.83373255758 14066.56439243359 16963.842149065476 21467.822011453085 2.3544444709001033 1.4126546045475339 0.8893616516718043 1.107307023236942 0.8902897636705548 1.1314501484619865 0.7019731076826434 0.6552394735213044 0.7901985650903601 1.0 14.389888211516382 -2.0635408810811913 0.8594560096611523 0.8511814315100723 199.9999999521294 0.8998866182682723 0.149166264877057 72.4464493531737 0.5522140665841069 0.05410998662287576 27753.8197050049 0.00863891336892283 2.0635408810811913 199.14881852061933 up TTFDEAMADLHTLSEDSYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTFDEAMADLHTLSEDSYK 19 0 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 ; 99.37100000000001 0.00034169 5946200.0 40614.0 54672.0 50577.0 53964.0 60041.0 43139.0 52369.0 39929.0 43878.0 37706.0 False True 47489.148036935425 60099.474845339406 51782.94749434064 50940.57203364853 48276.39705792483 40876.71489813072 47408.22920127326 38880.906058272565 44519.63274097944 44541.79931946826 1.066170400893054 1.349282601142501 1.1625697274359421 1.1436577060636055 1.0838447883901325 0.9177158427065246 1.0643537065318363 0.8729082940589372 0.9995023420960202 1.0 15.442872218250848 -6.350220056519803 1.5871375723558903 0.9665765361025213 1.2070498940713486 0.5872980822089673 0.08226402313589475 0.24521689131900062 1.2329642173459896 0.029350934811528968 0.03702186258068376 4.464573154150183e-07 6.350220056519803 0.2404733579688273 TTFDEAMADLHTLSEDSYK ddPTM_PC-9_Lapatinib_30min_R1 2 TTFDEAMADLHTLSEDSYK 19 0 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 ; 96.805 0.00053598 1003500.0 18417.9 23647.9 24709.4 18228.4 22100.8 19085.6 18304.6 21989.5 21043.0 19273.1 False True 18155.257368570805 23593.14474047264 22677.888513042308 19568.97734415981 20800.874395844596 18269.35337870661 19252.32262290434 23011.212446616446 18672.915747386367 22604.4296552085 0.8031725482791591 1.0437398819764656 1.0032497549796344 0.8657142711694449 0.9202123085220896 0.8082200549792239 0.8517057460225823 1.0179957113544873 0.8260732976770225 1.0 14.464317896233863 -2.547131202713744 17.91011617648524 0.9147471862285262 0.33957920513104467 0.0 0.08970419497950033 0.0 0.0 0.02025955948698181 0.0 0.002837061807234003 2.547131202713744 -0.5751679810974816 TTFS(ph)PPVVAATVK ddPTM_PC-9_AZD4547_30min_R2 1 TTFSPPVVAATVK 13 0 A0A1B0GV05;Q684P5-3;Q684P5-2;Q684P5 A0A1B0GV05 RAP1GAP2 Rap1 GTPase-activating protein 2 1 T(0.005)T(0.122)FS(0.873)PPVVAATVK 211.82 1.2437e-10 9131700.0 59394.0 43790.0 63676.0 85986.0 72008.0 77268.0 57258.0 79779.0 56182.0 68134.0 True False 78280.05652805422 57944.261139877475 62831.61463484074 66163.25617045719 62010.932148555796 72436.41974524452 62353.851076556304 67450.98868904129 59151.665822173796 65748.64939837567 1.1905956585320845 0.8812996414388552 0.9556335409133592 1.0063059359526823 0.9431514216030085 1.101717227776759 0.9483670257429923 1.0258916237252422 0.8996635879737958 1.0 16.004673638573728 -4.744652322247295 24.995996833393626 0.9770986557205757 1.1905962847959461 0.5339803337458322 0.06074570703976967 811.9345317103837 1208909.1264009178 0.014641483164309212 0.4101244876418381 1.800311591525565e-05 4.744652322247295 0.2134976290753704 TTFS(ph)PPVVAATVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTFSPPVVAATVK 13 0 A0A1B0GV05;Q684P5-3;Q684P5-2;Q684P5 A0A1B0GV05 RAP1GAP2 Rap1 GTPase-activating protein 2 1 T(0.009)T(0.006)FS(0.985)PPVVAATVK 69.92 0.029401999999999998 6696700.0 49601.0 42230.0 41675.0 47642.0 59593.0 57951.0 56442.0 58196.0 44679.0 39627.0 True False 57997.46963559449 46422.315311652834 42668.690053317616 44972.77319744801 47916.17944192994 54911.947543095 51095.40515530688 56668.41666375891 45332.34585063634 46811.06141284061 1.2389693351342248 0.9916954222046087 0.9115087068205912 0.9607296190278578 1.0236080532193657 1.1730549550844462 1.0915241742690125 1.2105774779166694 0.9684109798501889 1.0 15.514561857218004 -6.608752700955854 9.898803956386365 1.1019404091101725 1.0122851450972616 0.0715041983842255 0.1047926692833046 0.6989271089243732 74.68560790541504 0.034603749104193 0.034592257243921946 2.461769003078483e-07 6.608752700955854 -0.0896552640129109 TTGFGMIYDSLDYAK ddPTM_PC-9_Lapatinib_30min_R1 1 TTGFGMIYDSLDYAK 15 0 E7ETK0;A0A2R8Y849;A0A2R8YD14;P62847-2;P62847-3;P62847;P62847-4;A0A2R8Y8A0 E7ETK0 RPS24 40S ribosomal protein S24 0 94.402 0.040582 3474400.0 13691.0 13119.0 13754.0 9888.0 12480.0 11262.0 12921.0 11929.0 15270.0 14137.0 False True 13495.763829378096 13088.623761528954 12623.199211975361 10615.19650540104 11745.950936624036 10780.350513004241 13589.986157061443 12483.26488895554 13550.131799771401 16580.561613631577 0.813950947130926 0.7893956831213875 0.7613251894674845 0.6402193576286246 0.7084169529557549 0.6501800580832715 0.819633645333735 0.7528855282376276 0.8172299657588962 1.0 14.01720525390295 -8.83943151495279 0.9777070973745124 1.0001096217901575 0.7328858272596351 0.6513913253138591 0.05754175352148167 0.7156806957021528 1.2352198566543489 0.05965119579144939 0.019396884419001312 1.4473330688858082e-09 8.83943151495279 -0.26722379453052236 TTGIVMDSGDGVTHTVPIYEGYALPHAILR ddPTM_PC-9_Lapatinib_30min_R1 5 TTGIVMDSGDGVTHTVPIYEGYALPHAILR 30 0 P60709;A0A2R8Y793;A0A2R8YEA7;P63261;I3L3I0;I3L1U9;I3L4N8 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ;;;; 137.62 3.7372e-16 28320400.0 63657.4 61007.8 61308.4 66358.9 73088.4 65532.7 61056.7 52787.7 68298.7 54517.4 False True 62749.63380266255 60866.540187408034 56267.86000926785 71239.15487280124 68789.48400932315 62730.01918518497 64217.917173272464 55240.40925297329 60606.1811888047 63940.65995013069 0.9813729456593495 0.9519223016290377 0.8800012394797443 1.1141448169030923 1.0758331875675697 0.9810661828343664 1.00433616455254 0.8639324225939645 0.9478504168720395 1.0 15.964446014219451 -9.860747868704516 7.039191868434662 1.0000100262696716 0.9786063338182003 0.008172509398467365 0.07282204702004437 0.0 0.0 0.07603197023459407 0.018440461423591143 1.3780092451669048e-10 9.860747868704516 -0.021403692451471334 TTHFVEGGDAGNREDQINR ddPTM_PC-9_AZD4547_30min_R2 4 TTHFVEGGDAGNREDQINR 19 1 A8MUD9;P18124 A8MUD9 RPL7 60S ribosomal protein L7 0 ;;; 89.866 0.00046465 135678000.0 47456.600000000006 46983.899999999994 72045.4 106283.0 73050.0 71924.8 68022.6 76261.0 65186.0 65703.9 False True 62546.811641399116 62170.52685475885 71090.03092237192 81781.09640598111 62908.26843478509 67427.33088591363 74076.47962276282 64476.61475344366 68631.59888014339 63403.62645971073 0.9864863436659089 0.9805515918598845 1.1212297291472035 1.2898488773027545 0.9921872288292467 1.0634617395072776 1.1683319040092142 1.01692313758133 1.082455416390965 1.0 15.952277739248762 -5.254829947945048 24.002966849536733 1.0976452503446765 0.9835189389130802 0.20640744153024482 0.08431131014054391 452.1185038154373 1641902.7538944252 0.021885997071585308 0.0549615925319783 5.561219693879502e-06 5.254829947945048 -0.11412631143159635 TTHFVEGGDAGNREDQINR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TTHFVEGGDAGNREDQINR 19 1 A8MUD9;P18124 A8MUD9 RPL7 60S ribosomal protein L7 0 ;;; 85.473 0.00058245 109095000.0 43778.299999999996 41925.700000000004 48721.5 62557.0 59993.5 49931.5 45475.3 43513.8 41769.600000000006 36645.2 False True 51189.10152916163 46087.80641870151 49883.20533731772 59052.1341025304 48238.20434194325 47313.004240617855 41167.55037133922 42371.60885668214 42380.40137968038 43288.68467675642 1.1825053570326494 1.0646617415808908 1.152338208236255 1.3641471101162392 1.114337492629903 1.0929646995262545 0.9510002597386348 0.9788148836832944 0.9790179973390658 1.0 15.401702344591522 -6.96257363292663 2.286162974097604 0.9758456750670058 1.1808070836323772 0.6229659407970488 0.07288686787320428 0.2175124406133467 2.296766617993353 0.03255860375326509 0.02635422978945579 1.0899996715470929e-07 6.96257363292663 0.20496140856537137 TTHFVEGGDAGNREDQINR ddPTM_PC-9_Lapatinib_30min_R1 4 TTHFVEGGDAGNREDQINR 19 1 A8MUD9;P18124 A8MUD9 RPL7 60S ribosomal protein L7 0 ;;; 93.90899999999999 0.00035639 117088000.0 48132.0 45274.7 60059.6 54030.8 50550.0 57071.9 47589.2 41476.5 55120.0 29922.800000000003 False True 47445.628853672235 45169.86921381927 55121.73152476042 58004.405273465076 47576.74838512383 54631.06787809687 50053.135920256034 43403.649607407526 48911.80516066796 35094.91611037524 1.3519231305313109 1.2870772812722449 1.5706471943514513 1.6527865486567446 1.3556592708611301 1.5566661480620003 1.426221842583594 1.2367503450044135 1.3937005863424183 1.0 15.098974434763997 -8.890834244970476 0.6851619868733912 0.9978172633759558 1.4640672662144087 0.5506713094696258 0.11974753658741684 1.0460754861541313 0.922200011938762 0.1364758989278948 0.048402377347426126 1.285777302578511e-09 8.890834244970476 0.46625000283845297 TTHLAGALS(ph)PGEAWPFESV ddPTM_PC-9_AZD4547_30min_R2 1 TTHLAGALSPGEAWPFESV 19 0 Q9Y3X0 Q9Y3X0 CCDC9 Coiled-coil domain-containing protein 9 1 T(0.001)T(0.001)HLAGALS(0.998)PGEAWPFESV 128.74 3.5194e-05 611810.0 2898.1 3062.7 1934.9 5132.8 3182.6 3282.1 3035.8 2453.5 1477.5 1275.3 True False 3819.6355157752323 4052.6578806371936 1909.2419617587984 3949.512260969486 2740.750925674839 3076.8697681558583 3305.980318876131 2074.367950821181 1555.5976336239678 1230.652135171109 3.1037491477997174 3.2930978339169052 1.5514066950311176 3.209284043878369 2.2270720111282842 2.5001945555703706 2.68636459027999 1.6855843268274688 1.264043338621989 1.0 10.265207301734733 -7.970650743646774 1.989253373031223 1.0740264161233946 2.648870412565235 0.6198747212130044 0.4906020088935132 0.2312006433555547 1.6856115246766528 0.4016508843668326 0.13757643933295166 1.0699149508945235e-08 7.970650743646774 1.5748439964418404 TTHLAGALS(ph)PGEAWPFESV ddPTM_PC-9_Lapatinib_30min_R1 4 TTHLAGALSPGEAWPFESV 19 0 Q9Y3X0 Q9Y3X0 CCDC9 Coiled-coil domain-containing protein 9 1 TTHLAGALS(0.999)PGEAWPFESV;T(0.007)T(0.007)HLAGALS(0.986)PGEAWPFESV;TTHLAGALS(1)PGEAWPFESV;TTHLAGALS(1)PGEAWPFESV 110.6 0.00014264 9624300.0 38140.85 31197.37 36797.61 30643.69 41405.5 40227.520000000004 33255.3 32863.22 42329.61 33229.97 True False 37596.95448482475 31125.134406525685 33772.252548682285 32897.32918695314 38970.1098963451 38507.082744529245 34977.0967145674 34390.16517428294 37562.00357124569 38973.726038348235 0.9646743667216009 0.798618391680079 0.8665389733445564 0.8440899172582006 0.9999072159023343 0.9880267210438172 0.8974532401688166 0.8823935679243167 0.9637775852964768 1.0 15.250214244853627 -6.247322893451612 24.873270679542212 0.9481274271461537 0.8633515895854024 0.37904830820593327 0.053791701926198345 849.2969079360917 1496461.2630018694 0.016165439536758697 0.02076612250440303 5.658184524515974e-07 6.247322893451612 -0.08477583756075135 TTHLAGALS(ph)PGGGQSAPAFPESGPSLR ddPTM_PC-9_AZD4547_30min_R2 2 TTHLAGALSPGGGQSAPAFPESGPSLR 27 0 A0A2R8Y4Z8 A0A2R8Y4Z8 1 TTHLAGALS(1)PGGGQSAPAFPESGPSLR;T(0.001)T(0.001)HLAGALS(0.769)PGGGQS(0.229)APAFPESGPS(0.001)LR 115.52 4.1853e-12 100287000.0 34400.0 28591.0 52473.0 76647.0 67541.0 61705.0 51230.0 72053.0 53712.0 67803.0 True False 45338.48443555019 37832.48162252199 51777.17373475084 58977.2183343454 58164.09799252316 57846.57659548991 55789.370754339645 60918.864463223385 56551.10666477867 65429.23760762703 0.6929392133137912 0.5782198143496615 0.7913461264099342 0.90138935574989 0.8889618788060434 0.884108981100932 0.8526672905605784 0.9310648677972999 0.8643094239292581 1.0 15.99764783982433 -5.48993230506977 3.336702291274456 0.8961445946903884 0.6369837712651388 0.8331048086971702 0.04751169257286835 0.08304416616178467 1.8777111279298568 0.012149659254900028 0.02627182194286777 3.2364410048413724e-06 5.48993230506977 -0.2591608234252496 TTHLAGALS(ph)PGGGQSAPAFPESGPSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TTHLAGALSPGGGQSAPAFPESGPSLR 27 0 A0A2R8Y4Z8 A0A2R8Y4Z8 1 TTHLAGALS(1)PGGGQSAPAFPESGPSLR;TTHLAGALS(1)PGGGQSAPAFPESGPSLR;TTHLAGALS(1)PGGGQSAPAFPESGPSLR 127.93 7.8812e-11 65959200.0 45836.0 43844.4 44369.7 54658.1 60092.1 56967.0 62687.0 64833.4 53737.4 46901.9 True False 53595.12949773412 48196.98227445496 45427.64192102431 51595.783860951124 48317.48437974928 53979.55023532795 56748.83354542223 63131.59194666556 54523.20781382717 55404.84319476392 0.9673365432933699 0.8699055803664806 0.819921857035731 0.931250426602186 0.872080518482824 0.9742749392065663 1.0242576329642121 1.139459807236344 0.9840873950705438 1.0 15.75772447401281 -7.029665008152232 2.3975530953677056 1.0496832772875666 0.8885725264849177 0.6128852446495062 0.05389633500517438 0.18467828426671717 2.116980517385816 0.022532723909901513 0.01751809231803186 9.339744416250235e-08 7.029665008152232 -0.16111075080264892 TTHLAGALS(ph)PGGGQSAPAFPESGPSLR ddPTM_PC-9_Lapatinib_30min_R1 2 TTHLAGALSPGGGQSAPAFPESGPSLR 27 0 A0A2R8Y4Z8 A0A2R8Y4Z8 1 TTHLAGALS(1)PGGGQSAPAFPESGPSLR;TTHLAGALS(0.998)PGGGQS(0.001)APAFPESGPSLR 125.2 2.9201e-11 62897000.0 63165.0 47013.0 57384.0 44554.0 77335.0 70972.0 69794.0 61867.0 70252.0 65418.0 True False 62264.255516957695 46904.1442869701 52666.10902864576 47830.64978778702 72786.30734645986 67936.69300381253 73407.59181533522 64741.566676587485 62339.479973643785 76725.41413599426 0.8115206182738297 0.6113247457202831 0.6864232617278043 0.6234003468916851 0.9486596868339816 0.8854522816051028 0.9567571924111318 0.8438086311510076 0.8125010555583096 1.0 16.227416907407488 -6.262621152749821 24.99966951840693 0.9013777363894333 0.6782682046629247 0.6998829215016469 0.07197939752803414 59.466641020473645 1257979.755457907 0.021415757531999875 0.025660990592589222 5.462341486808262e-07 6.262621152749821 -0.2231095317265086 TTHS(ph)PYEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTHSPYEER 9 0 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 T(0.11)T(0.077)HS(0.813)PYEER;T(0.365)T(0.03)HS(0.605)PYEER 90.685 0.008382299999999999 80376000.0 58679.0 76415.0 69011.0 66986.0 61049.0 62008.0 68659.0 36012.0 48331.0 50068.0 True False 68612.19573692164 84000.97619085842 70656.48396567498 63232.9915915421 49086.8866939134 58756.191321154634 62155.12247188646 35066.723157868 49037.7494417311 59144.93206193008 1.1600688908574361 1.4202565336097068 1.1946329381474523 1.0691193545599385 0.829942397135819 0.9934273195145715 1.0508951537353097 0.5928948083184875 0.8291116031781752 1.0 15.85196693353529 -5.910052657825716 1.9404877629492399 0.8737350996863967 1.293270892527542 0.6081121741050892 0.13563154101292924 0.22289404764697485 1.7057240538888665 0.04463622748220118 0.07738894021339321 1.2301196108439329e-06 5.910052657825716 0.4195357928411453 TTHS(ph)PYEER ddPTM_PC-9_Lapatinib_30min_R1 1 TTHSPYEER 9 0 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 TT(0.004)HS(0.996)PYEER 99.28299999999999 0.0067348 0.0 17328.0 20140.0 19062.0 17724.0 21251.0 17768.0 18750.0 23230.0 23264.0 16122.0 True False 17080.899542433974 20093.367067397918 17494.795941447886 19027.482085530748 20001.057961073515 17008.104059230995 19720.783255545404 24309.350605284348 20643.763339219517 18908.666218785325 0.9033370912996758 1.0626538559042107 0.9252263347938952 1.0062836725430893 1.0577720146756266 0.8994872437027756 1.0429494617633717 1.2856195314894059 1.091762004805522 1.0 14.206759981472315 -7.531919361336166 24.955532876026247 1.146071404168414 0.9816105442494784 0.375836485858707 0.08531561757400284 177.97567614253242 491272.6223141577 0.03727500576414234 0.021559313055731517 2.9381951577102015e-08 7.531919361336166 -0.16446085991893555 TTIFS(ph)PEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTIFSPEGR 9 0 P25789;H0YMI6;H0YMA1;H0YMZ1;H0YL69;H0YLS6;H0YLC2 P25789 PSMA4 Proteasome subunit alpha type-4;Proteasome subunit alpha type 1 T(0.372)T(0.056)IFS(0.573)PEGR 72.289 0.032687 2103700.0 16961.0 15887.0 16738.0 18421.0 19950.0 16323.0 17103.0 20039.0 12183.0 12454.0 True False 19832.162304980113 17464.156366474745 17137.097399218495 17388.931091687784 16040.940712273285 15466.993145000772 15482.8800250029 19512.997483075564 12361.15332702841 14711.811614190246 1.3480435193889406 1.1870840127962032 1.164852966353168 1.181970755723607 1.0903443527512975 1.0513316477001458 1.0524115201467725 1.326349058484024 0.8402196582714182 1.0 13.84468729071607 -1.5228787452803376 0.2886423149942949 1.0362720372793859 3.2547727181530335 0.39488019319163825 0.11208018173799296 60.13427578140842 0.8526635586252213 0.11620019063496094 67.98050573153412 0.029999999999999995 1.5228787452803376 2.218500680873648 TTIPEEEEEEEEAAGVVVEEELFHQQGT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTIPEEEEEEEEAAGVVVEEELFHQQGTPR 30 0 P20700 P20700 LMNB1 Lamin-B1 1 TTIPEEEEEEEEAAGVVVEEELFHQQGT(1)PR;TTIPEEEEEEEEAAGVVVEEELFHQQGT(1)PR 126.76 2.4525e-15 42592400.0 100364.0 104957.3 118847.5 130062.5 123732.8 106457.2 113655.3 122092.1 107594.8 94471.9 True False 117353.64292064281 115376.76710536926 121681.27513165379 122775.51979331402 99488.24606333657 100874.39702481001 102889.04719088544 118887.31174227325 109168.17040063678 111598.90763085101 1.0515662331465414 1.0338521187592151 1.0903446791267297 1.10014983479438 0.8914804649560342 0.9039012940743494 0.9219538916207297 1.0653089198285968 0.9782189872480234 1.0 16.76796338006926 -6.249814952022191 24.83746785580113 0.9586877376488221 1.0679953884811382 0.5290301974094329 0.05029222862672194 619.964423487899 1324653.273447135 0.01647876168001807 0.021085936864565617 5.625809835373318e-07 6.249814952022191 0.10930765083231608 TTIPEEEEEEEEAAGVVVEEELFHQQGT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 TTIPEEEEEEEEAAGVVVEEELFHQQGTPR 30 0 P20700 P20700 LMNB1 Lamin-B1 1 TTIPEEEEEEEEAAGVVVEEELFHQQGT(1)PR 51.473 0.018435 2346500.0 3808.8 2379.1 3575.9 2106.5 3243.3 3433.2 2810.9 2077.2 3845.3 2176.0 True False 3754.485813551626 2373.5913401214684 3281.9033053731746 2261.4190370780016 3052.535470573136 3286.370039180089 2956.434648160669 2173.714295191419 3412.201821195876 2552.118700662255 1.4711250744635687 0.9300473914107287 1.285952453748153 0.8860947715681018 1.1960789558028893 1.2877026598830617 1.1584236451829208 0.8517293081342012 1.3370074911917054 1.0 11.317479715988332 -6.152888848539919 0.017354278708072997 6.690477182127997e-05 2.2962517591222795 0.06071269161506554 0.19535522159436114 4212.2623641538685 19.750689698544758 1213.627105875024 1399.932310300856 7.032522842153568e-07 6.152888848539919 2.296184854350458 TTITTTTTS(ph)SSGLGSPMIVGSPR ddPTM_PC-9_AZD4547_30min_R2 2 TTITTTTTSSSGLGSPMIVGSPR 23 0 A0A494C017;C9JJV6;C9JZL8;A0A499FIY8;C9JC07;Q96S97 A0A494C017 MYADM Myeloid-associated differentiation marker 1 TTITTTT(0.001)T(0.036)S(0.96)S(0.001)S(0.001)GLGSPMIVGSPR;TTITT(0.006)T(0.006)T(0.019)T(0.125)S(0.84)S(0.002)S(0.002)GLGSPMIVGSPR 177.41 5.6198000000000005e-42 0.0 15158.5 36383.0 35756.0 32054.0 30563.0 20868.2 27051.0 36572.0 26114.0 21988.3 True False 19978.587683612994 48143.093241657036 35281.852077444615 24664.445529363307 26319.855005781465 19563.308155092815 29458.486595269223 30920.63774095465 27494.33272721238 21218.49630971763 0.9415647269247452 2.268921064854558 1.6627875775196315 1.1624030831094994 1.2404203682297468 0.9219931454866209 1.3883399730723542 1.4572492456401656 1.2957719682813031 1.0 14.373034800016086 -5.75360670499972 21.532270062577304 1.2252723261144662 1.6888753196828978 0.23548326572541245 0.33584062031160516 40.563139625489875 111500.57525132077 0.08873354806236425 0.14934642662026726 1.763572406189001e-06 5.75360670499972 0.4636029935684316 TTITTTTTS(ph)SSGLGSPMIVGSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTITTTTTSSSGLGSPMIVGSPR 23 0 A0A494C017;C9JJV6;C9JZL8;A0A499FIY8;C9JC07;Q96S97 A0A494C017 MYADM Myeloid-associated differentiation marker 1 TTITTTT(0.001)T(0.22)S(0.777)S(0.001)S(0.001)GLGSPMIVGSPR;TTITTTT(0.001)T(0.069)S(0.873)S(0.028)S(0.028)GLGSPMIVGSPR 178.03 5.1597e-42 5105800.0 34629.0 29159.0 24866.0 22663.4 50070.0 18798.3 21646.0 19149.2 22464.0 18976.5 True False 40491.0057460737 32053.71281488243 25458.89974483013 21393.643173734155 40259.14293050241 17812.484055484158 19595.53417653118 18646.553790254537 22792.493502287314 22416.789232108666 1.80628034313123 1.4298975862685244 1.1357067901751112 0.9543580462045381 1.7959370770563905 0.7946046095651585 0.8741454440078125 0.8318119779413442 1.0167599501555962 1.0 14.452292034560244 -6.78805741193841 24.999943835637936 0.8911200337015662 1.382583632844446 0.5119775080632644 0.2525283208267485 203.00115887608717 190659.40044975065 0.09162172054534795 0.08082543196857916 1.6290806606633853e-07 6.78805741193841 0.49146359914287985 TTITTTTTSSSGLGS(ph)PMIVGSPR ddPTM_PC-9_Lapatinib_30min_R1 1 TTITTTTTSSSGLGSPMIVGSPR 23 0 A0A494C017;C9JJV6;C9JZL8;A0A499FIY8;C9JC07;Q96S97 A0A494C017 MYADM Myeloid-associated differentiation marker 1 TTITTTTTSSSGLGS(0.972)PMIVGS(0.027)PR 167.89 2.0217999999999998e-32 0.0 11569.0 13407.0 7211.2 5660.8 9718.6 7496.1 5720.2 5284.5 9343.3 4760.2 True False 11404.02393850524 13375.956915223629 6618.322972036983 6077.1141158752225 9146.971055502752 7175.50927726257 6016.363966846446 5530.037162015718 8290.959164689204 5582.9942274321975 2.0426358104529734 2.3958392880831747 1.1854432769279375 1.088504459849726 1.6383629792341277 1.2852439004872163 1.0776231752640677 0.990514576361861 1.4850381044550154 1.0 12.446823349098551 -5.266223649252618 24.999055913872347 1.226158563333011 2.2192375863882274 0.7797626723450926 0.21263667695931956 157.70319777138266 824044.3357905649 0.05574575852575706 0.12237383285797605 5.417218472810328e-06 5.266223649252618 0.9930790230552164 TTKS(ph)PSDSGYSYETIGK ddPTM_PC-9_AZD4547_30min_R2 2 TTKSPSDSGYSYETIGK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.043)T(0.007)KS(0.947)PS(0.002)DSGYSYETIGK;T(0.234)T(0.157)KS(0.567)PS(0.039)DS(0.002)GYSYETIGK 189.52 7.1933e-08 321236000.0 156406.0 125845.0 168837.0 252131.0 193069.0 191420.0 162207.0 191607.0 154904.0 184009.0 True False 206139.8545531002 166521.935216896 166598.11106386414 194006.09333511884 166264.70196352492 179450.47713975635 176643.1087634035 161998.54084083732 163091.90919721636 177566.90091798102 1.160913737230325 0.9377982853561951 0.9382272833652516 1.0925802744326272 0.9363496299365125 1.0106076989125656 0.9947974980145414 0.9123239748136687 0.9184814757371322 1.0 17.438003157860372 -4.755047075078776 24.995287409405524 0.9721370193591554 1.16091405263948 0.5421037418802074 0.05229024515582156 172.46826788825015 674324.9814561672 0.01321448340323622 0.12158120344270042 1.7577330752547378e-05 4.755047075078776 0.1887770332803247 TTKS(ph)PSDSGYSYETIGK ddPTM_PC-9_Lapatinib_30min_R1 2 TTKSPSDSGYSYETIGK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.038)T(0.008)KS(0.477)PS(0.477)DS(0.001)GYSYETIGK;T(0.018)T(0.024)KS(0.951)PS(0.007)DSGYSYETIGK 137.91 0.00016824 364844000.0 246269.0 177349.0 214205.0 174026.0 192929.0 192648.0 169300.0 161707.0 215090.0 144057.0 True False 242757.1588997965 176938.35928679013 196593.89175521192 186824.45257371783 181581.29553300777 184408.8941244223 178065.525608738 169220.4975604269 190864.29920188803 168957.06050611328 1.436797954300424 1.0472386223858816 1.163573106482275 1.1057510826365144 1.0747186000341058 1.0914542048259057 1.053909940640185 1.001559195298051 1.1296615757290718 1.0 17.366297114635593 -4.758458006851653 24.999999998200803 1.0779551449712896 1.4367984409876347 0.828864706242991 0.04940075590847264 32.310913049131564 270891.77499543544 0.012199334979804523 0.08349224787338726 1.7439819798096538e-05 4.758458006851653 0.358843296016345 TTKSPS(ph)DSGYSYETIGK ddPTM_PC-9_AZD4547_30min_R2 1 TTKSPSDSGYSYETIGK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 TTKS(0.017)PS(0.981)DS(0.002)GYSYETIGK 151.55 0.00020652 121710000.0 60319.0 49588.0 54100.0 85351.0 86091.0 77561.0 56225.0 68516.0 58610.0 74779.0 True False 79499.18728685901 65616.35125380772 53382.59865168793 65674.64560980487 74138.75068883089 72711.09840892622 61228.91607774247 57928.42654104915 61708.00494531352 72161.00997095623 1.101691721316765 0.9093047794122803 0.7397706694123829 0.9101126167197211 1.0274073314476981 1.0076230701065767 0.8485041451385759 0.8027662939358042 0.8551433103576308 1.0 16.138931910353016 -7.293569289596854 23.79105584777577 0.860167265337678 0.9397421083471689 0.09668545884010926 0.10164789664745172 891.025391632528 659767.7093907607 0.045218843046819696 0.03049051559660389 5.086636583289681e-08 7.293569289596854 0.07957484300949091 TTKSPS(ph)DSGYSYETIGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TTKSPSDSGYSYETIGK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.003)T(0.001)KS(0.003)PS(0.821)DS(0.17)GYS(0.002)YETIGK;T(0.005)T(0.001)KS(0.153)PS(0.81)DS(0.029)GYS(0.001)YETIGK;TTKS(0.039)PS(0.89)DS(0.039)GY(0.006)S(0.021)Y(0.004)ETIGK 181.72 1.9119e-32 78611000.0 63159.0 48289.0 56427.0 79315.0 80763.0 69925.0 76808.0 85077.0 67828.0 52890.0 True False 73850.57125288824 53082.812789116855 57772.43368058921 74871.23769269942 64938.069912046536 66258.00990407265 69532.19019823562 82843.81889653257 68819.856182031 62478.53832299034 1.1820150284423878 0.8496167518308263 0.9246764606100041 1.1983513011402975 1.0393660231989 1.0604923175626144 1.112897197414904 1.3259564183185826 1.1014959381133158 1.0 15.931073081767497 -6.272282241632196 0.959795572947953 1.1473770941047767 0.9880338410844797 0.10912096957137296 0.12381675190930622 0.9831851320312333 1.9239070191456416 0.059827500546572106 0.09357455707059494 5.342170667002936e-07 6.272282241632196 -0.15934325302029706 TTKT(ph)PEDGDYSYEIIEK ddPTM_PC-9_AZD4547_30min_R2 3 TTKTPEDGDYSYEIIEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.183)T(0.13)KT(0.687)PEDGDYSYEIIEK;T(0.301)T(0.301)KT(0.397)PEDGDYSYEIIEK;T(0.121)T(0.121)KT(0.758)PEDGDYSYEIIEK 90.561 0.0017047999999999998 197996000.0 210942.0 171677.0 211134.0 266188.0 255164.0 244740.0 234392.0 199822.0 210075.0 230617.0 True False 278017.1681338315 227168.23292328717 208334.22520749498 204822.46916360367 219738.8830512458 229436.36911077236 255252.4339225295 168944.1013527576 221179.1356233874 222543.1690243521 1.2492729808453886 1.0207827718065297 0.936151966024613 0.9203718544207065 0.9873989123755156 1.0309746649004803 1.1469794154616273 0.7591520426954586 0.9938707019993257 1.0 17.763725692297584 -4.772417774498081 3.3622834897250042 0.9705024299630758 1.289138396856981 0.44678501821289696 0.09216640047514321 0.30371066077042247 5.3891485397292325 0.0236992450378454 0.2556743879997263 1.6888155747244062e-05 4.772417774498081 0.31863596689390516 TTKT(ph)PEDGDYSYEIIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTKTPEDGDYSYEIIEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.157)T(0.157)KT(0.687)PEDGDYSYEIIEK;T(0.133)T(0.133)KT(0.732)PEDGDY(0.001)SYEIIEK 84.975 0.0023886999999999997 14768000.0 43520.0 39967.0 38346.0 47674.0 50420.0 49239.0 49258.0 53418.0 46925.0 39091.0 True False 50887.076440819204 43934.65962729884 39260.314068014806 45002.980341193375 40540.56294299843 46656.82015969446 44591.9256429628 52015.83410104944 47611.189351621804 46177.88885581424 1.1019792741004015 0.9514220055507592 0.8501972489604525 0.9745569028006152 0.8779215323069925 1.0103714421717205 0.9656553547130868 1.1264229567415607 1.0310386752474305 1.0 15.494914597553892 -7.645398220823696 8.003302009354652 1.0586855858312627 0.9554127710930369 0.2506866838240772 0.0712579586358331 0.2998769798151802 19.676712360051848 0.03381265572643333 0.019415670754868993 2.2625687224190953e-08 7.645398220823696 -0.1032728147382258 TTKT(ph)PEDGDYSYEIIEK ddPTM_PC-9_Lapatinib_30min_R1 2 TTKTPEDGDYSYEIIEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.055)T(0.055)KT(0.89)PEDGDYSYEIIEK;T(0.089)T(0.089)KT(0.823)PEDGDYSYEIIEK 86.539 0.0021972 141359000.0 361240.0 264040.0 287610.0 283780.0 319910.0 287620.0 241240.0 262920.0 294627.0 234479.0 True False 356088.6513566966 263428.6316025686 263963.8160067063 304650.12786232843 301093.522767259 275319.16307496704 253730.22680361455 275136.22303664935 261443.00470014766 275008.3827263717 1.294828353326954 0.9578930976248651 0.959839163409595 1.1077848785629554 1.0948521633496588 1.00113007591083 0.9226272460795185 1.000464859685404 0.9506728562535444 1.0 18.069116069559364 -6.9201083583904355 4.902699411499255 0.9675417035774265 1.0701109286503414 0.26254715941212525 0.09044646462690993 0.33011070200341236 14.251930356278557 0.0327550477612405 0.028655271091244276 1.2019645017524012e-07 6.9201083583904355 0.10256922507291488 TTNESLLTS(ph)FPK ddPTM_PC-9_AZD4547_30min_R2 2 TTNESLLTSFPK 12 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 TTNESLLT(0.026)S(0.974)FPK;TTNESLLT(0.038)S(0.962)FPK 134.04 5.6200000000000004e-05 7737900.0 51963.0 49626.0 56095.0 72177.0 57961.0 53600.0 50430.0 55919.0 53149.0 55971.0 True False 68486.1531024563 65666.63401067734 55351.14364817812 55537.707773533795 49914.1156296862 50248.38352675241 54918.17230414497 47278.003440786466 55958.34763416602 54011.47232624649 1.2679927088226393 1.2157904826965271 1.0248034586770676 1.028257616049945 0.9241391408141784 0.9303279722359016 1.0167871738882015 0.8753326173967685 1.0360455885401492 1.0 15.720978255534648 -5.244460438670855 1.4932304055873016 0.96172492922291 1.2987053013916035 0.8295425615445917 0.04838186710478749 0.19616804057539708 0.6949817535534577 0.01367514278997498 0.07534642666775176 5.695601048896362e-06 5.244460438670855 0.3369803721686935 TTNESLLTS(ph)FPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTNESLLTSFPK 12 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 TTNESLLT(0.046)S(0.953)FPK;TTNESLLT(0.249)S(0.751)FPK 96.37100000000001 0.0043046000000000004 5190200.0 71892.0 78450.0 47148.0 74241.0 70769.0 62997.0 73111.0 53526.0 61240.0 53345.0 True False 84061.89566827616 86237.99754201205 48272.18712978571 70081.51746256952 56902.32246951716 59693.326420119694 66185.39680219755 52120.99921548488 62135.51914530247 63016.02622121237 1.3339764613716527 1.3685089764194418 0.7660303263225504 1.112122132496174 0.9029817632385517 0.9472721464627328 1.0502946753554305 0.8271070446828648 0.9860272516578725 1.0 15.943431160694713 -5.2459852271987 24.984757567595288 0.9505458508366084 1.3512428074655614 0.7379875151043209 0.09587169432338635 364.86727291911603 589879.411699437 0.022659296458965517 0.059484412834726476 5.675639111253658e-06 5.2459852271987 0.400696956628953 TTNESLLTS(ph)FPK ddPTM_PC-9_Lapatinib_30min_R1 2 TTNESLLTSFPK 12 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 TTNESLLT(0.023)S(0.977)FPK;TTNESLLT(0.026)S(0.974)FPK 163.33 0.00037887 7362400.0 82219.0 69656.0 71309.0 64960.0 74762.0 78970.0 74516.0 72477.0 64898.0 50769.0 True False 81046.5419828819 69494.71581165172 65446.24928070027 69737.37510020747 70364.64614774728 75592.63718806126 78374.07387041186 75844.54601029668 57588.503833763265 59544.35400455977 1.361112121170641 1.1671084013495214 1.099117630458944 1.1711836708290957 1.181718188467691 1.269518134032868 1.3162301477720315 1.273748742063583 0.9671530541645186 1.0 15.861677097785169 -8.266292684750796 24.849776880538403 0.9835764817614555 1.2241362444150565 0.634530083987269 0.0746921407693309 280.0699831027613 1433979.2899923818 0.0704106304399415 0.020462145558977858 5.416357419609819e-09 8.266292684750796 0.24055976265360102 TTNSS(ph)LEEIMDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTNSSLEEIMDK 12 0 Q709C8-3;Q709C8;Q709C8-4;Q709C8-2 Q709C8-3 VPS13C Vacuolar protein sorting-associated protein 13C 1 T(0.003)T(0.003)NS(0.218)S(0.776)LEEIMDK;T(0.008)T(0.009)NS(0.191)S(0.792)LEEIMDK 99.161 0.0097539 3250800.0 42165.0 42978.0 45617.0 56322.0 61350.0 51514.0 50386.0 45694.0 40172.0 41150.0 True False 49302.701703289094 47244.57180829308 46704.68228343586 53166.46093838768 49328.90790465999 48812.51515478585 45613.07331695 44494.58091679498 40759.43950204266 48610.1692567792 1.0142466577898885 0.971907165324349 0.9608006513353665 1.093731244948773 1.0147857672349196 1.0041626248396252 0.938344260354304 0.9153348280224254 0.8384961444329538 1.0 15.568970537035147 -7.370544569276882 2.5930548143670396 0.9087925590081356 1.01097743477495 0.4290988430541315 0.04922504506713305 0.26838212444571824 3.5111487054999477 0.024406995948543907 0.015026759152203532 4.2604495866595045e-08 7.370544569276882 0.10218487576681445 TTNSS(ph)LEEIMDK ddPTM_PC-9_Lapatinib_30min_R1 1 TTNSSLEEIMDK 12 0 Q709C8-3;Q709C8;Q709C8-4;Q709C8-2 Q709C8-3 VPS13C Vacuolar protein sorting-associated protein 13C 1 T(0.001)TNS(0.001)S(0.998)LEEIMDK 114.31 0.00077464 2095800.0 20759.0 15882.0 16078.0 15303.0 18289.0 17227.0 16542.0 12630.0 15881.0 17157.0 True False 20462.972853265626 15845.226204787179 14756.128902874781 16428.433669311496 17213.276977557452 16490.241368098395 17398.463819372377 13216.835908081854 14092.314545656169 20122.56458973451 1.0169167434902793 0.7874357234201943 0.7333125376276638 0.8164184836406206 0.855421628828503 0.8194900453449588 0.8646245731644053 0.6568166721067155 0.7003239812108909 1.0 14.296526565662436 TTPATGEQS(ph)PGAR ddPTM_PC-9_AZD4547_30min_R2 4 TTPATGEQSPGAR 13 0 O00308-4;O00308-2;O00308 O00308-4 WWP2 NEDD4-like E3 ubiquitin-protein ligase WWP2 1 T(0.007)T(0.001)PAT(0.045)GEQS(0.947)PGAR;TTPATGEQS(1)PGAR;TTPATGEQS(1)PGAR;TTPAT(0.003)GEQS(0.997)PGAR 188.63 2.7374000000000003e-05 99259000.0 47815.8 62299.8 80946.5 118889.0 95845.9 84123.3 77835.0 95312.3 73497.6 94575.9 True False 63020.22976957504 82436.99201101018 79873.09652049653 91480.97786673962 82539.35120566149 78863.05675253831 84762.16421362541 80583.9740937656 77382.53308767575 91264.82652766333 0.6905204575222957 0.903272324590708 0.8751794043709288 1.0023683969750468 0.9043938869553753 0.8641122736220189 0.928749524198494 0.8829685779256892 0.8478899925835096 1.0 16.477771332077232 -4.760481627862787 6.180345977454049 0.9093538007083373 0.6830584994925505 0.6388833903734445 0.04995895372399266 0.08301134098589244 13.084825680632852 0.012174316770570015 0.07930713895833 1.735874694735888e-05 4.760481627862787 -0.22629530121578678 TTPATGEQS(ph)PGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TTPATGEQSPGAR 13 0 O00308-4;O00308-2;O00308 O00308-4 WWP2 NEDD4-like E3 ubiquitin-protein ligase WWP2 1 TTPAT(0.07)GEQS(0.93)PGAR;T(0.022)T(0.004)PAT(0.033)GEQS(0.942)PGAR;T(0.019)TPAT(0.142)GEQS(0.839)PGAR;TTPATGEQS(1)PGAR;TTPAT(0.08)GEQS(0.919)PGAR 136.57 5.5877e-05 94216000.0 35558.9 33283.3 50866.9 50510.899999999994 54979.5 45994.2 45496.6 45965.9 37383.899999999994 35283.5 True False 41578.319449711526 36587.4460623333 52079.759809792486 47680.938031547266 44206.66164864309 43582.183183838395 41186.83268114057 44759.34382989682 37930.56881410964 41680.11924596766 0.9975575934498799 0.8778152923800224 1.2495108159948687 1.1439731674030695 1.0606174466000324 1.0456348007702676 0.9881649435330055 1.0738775377718492 0.910039834345705 1.0 15.347071784692744 -7.097376335522336 2.3061581661296917 0.9974411834658802 1.0699387310887079 0.11099706318084035 0.09675908764798599 0.8333323459372979 8.716035797163078 0.045961558062585214 0.03395652375997289 7.991414631923372e-08 7.097376335522336 0.07249754762282767 TTPATGEQS(ph)PGAR ddPTM_PC-9_Lapatinib_30min_R1 3 TTPATGEQSPGAR 13 0 O00308-4;O00308-2;O00308 O00308-4 WWP2 NEDD4-like E3 ubiquitin-protein ligase WWP2 1 T(0.008)T(0.005)PAT(0.041)GEQS(0.946)PGAR;T(0.001)T(0.014)PAT(0.019)GEQS(0.966)PGAR;TTPAT(0.005)GEQS(0.995)PGAR 82.925 0.0099679 84132000.0 22774.6 19731.5 23450.7 23773.5 20969.6 19165.0 19137.1 18661.0 22851.3 15877.9 True False 22449.830027649867 19685.81292404976 21522.673968319792 25521.88249607115 19736.209355819818 18345.357625797034 20127.92539945056 19528.058185329803 20277.545959143186 18622.373859028146 1.2055299822458545 1.0571054513818632 1.1557427711014177 1.3704956569593363 1.0598116816482923 0.9851245477441205 1.0808463814452163 1.0486342038430605 1.0888808329509834 1.0 14.184749369543669 -6.486908373627253 24.97853233885993 1.0436040954277548 1.1881110968261992 0.4820284713092775 0.07782106427424244 565.9845476696458 393030.9499244866 0.02495779078277499 0.028289233332209483 3.2590545247336744e-07 6.486908373627253 0.1445070013984444 TTPES(ph)PPYSSGSYDSIK ddPTM_PC-9_AZD4547_30min_R2 2 TTPESPPYSSGSYDSIK 17 0 A0A087WTU5;A0A087X0N3;Q96MY1-2;Q96MY1 A0A087WTU5 NOL4L Nucleolar protein 4-like 1 TTPES(0.999)PPYS(0.001)SGSYDSIK;T(0.001)T(0.001)PES(0.999)PPYSSGSYDSIK 168.55 1.8553e-05 93195000.0 28871.5 35076.0 36106.0 41287.0 36501.0 46823.0 40133.0 37744.0 35289.0 31999.0 True False 38052.03643549381 46413.631051435106 35627.21084875868 31768.920027791282 31433.46620312238 43895.15040808077 43704.75925207715 31911.532070835397 37154.30449607862 30878.72474973757 1.2323059564115322 1.503094166860941 1.15377856882064 1.028828757834673 1.0179651672107841 1.4215337830120016 1.4153680116744 1.033447214205522 1.203233125629464 1.0 14.914325551999369 -14.522878745020021 0.14491908645808682 0.22018259099438386 1.2974755819870234 0.15347918559311002 0.1647622063740024 297.69605049583237 2.5942892030927522 66.92862747425235 1.0040717953365474 3.000000001798202e-15 14.522878745020021 1.0772929909926394 TTPES(ph)PPYSSGSYDSIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTPESPPYSSGSYDSIK 17 0 A0A087WTU5;A0A087X0N3;Q96MY1-2;Q96MY1 A0A087WTU5 NOL4L Nucleolar protein 4-like 1 TTPES(0.988)PPYS(0.01)S(0.003)GSYDSIK 170.09 2.7151999999999997e-24 0.0 16282.0 17537.0 15265.0 17159.0 20725.0 15266.0 17598.0 12203.0 12002.0 13026.0 True False 19038.221015841395 19277.957462004633 15628.975492834885 16197.636860228591 16664.085025657343 14465.424085742927 15930.990041513243 11882.684180147264 12177.506544446773 15387.510686240736 1.237251521967427 1.2528314589079488 1.015692259230082 1.0526482931844368 1.082961719114067 0.9400756484073591 1.0353195111512403 0.7722291423506578 0.7913889902501061 1.0 13.909472238175098 -5.483826518713729 0.4454392123444951 0.8634571971416406 1.3891897140607086 0.6509669462767326 0.0890301254425357 1.7715436431559937 0.43147408964776146 0.07448962178188624 0.46354413647002607 3.2822637873712566e-06 5.483826518713729 0.525732516919068 TTPES(ph)PPYSSGSYDSIK ddPTM_PC-9_Lapatinib_30min_R1 2 TTPESPPYSSGSYDSIK 17 0 A0A087WTU5;A0A087X0N3;Q96MY1-2;Q96MY1 A0A087WTU5 NOL4L Nucleolar protein 4-like 1 T(0.114)T(0.387)PES(0.499)PPYSSGSYDSIK;T(0.001)TPES(0.983)PPY(0.001)S(0.011)S(0.004)GSYDSIK 186.96 2.5611999999999998e-08 85164000.0 33024.0 45938.0 50766.0 44486.0 51390.0 51460.0 45082.0 43773.0 47995.0 38849.0 True False 32553.071704140104 45831.63338342231 46592.215442426976 47757.64884094568 48367.34123662735 49259.17575911901 47416.1253720799 45806.853381192916 42589.29769024418 45563.9978869614 0.714447221793404 1.0058738369957105 1.0225664472642733 1.0481443915309288 1.0615254033814305 1.0810986314529487 1.0406489239533676 1.0053299865133436 0.934713801802531 1.0 15.475606717435005 -4.759289496020823 4.595906566212324 1.0284823446289426 0.6886282486728339 0.8542335371038461 0.038174371948171124 0.07539492821426308 3.6183638932007476 0.01029751605131474 0.08492183781644021 1.7406461905952546e-05 4.759289496020823 -0.3398540959561087 TTPES(ph)PPYSSGSYDSIKTEVSGCPEDLTVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTPESPPYSSGSYDSIKTEVSGCPEDLTVGR 31 1 A0A087WTU5;A0A087X0N3;Q96MY1-2;Q96MY1 A0A087WTU5 NOL4L Nucleolar protein 4-like 1 T(0.016)T(0.011)PES(0.185)PPY(0.143)S(0.163)S(0.163)GS(0.145)Y(0.129)DS(0.032)IKT(0.01)EVS(0.002)GCPEDLTVGR 69.016 3.2446999999999996e-05 6621200.0 10557.0 3262.1 7968.1 16255.0 16784.0 24925.0 16558.0 18453.0 16499.0 14739.0 True False 12344.091589745593 3585.939729532153 8158.089723187531 15344.285049421043 13495.295684952127 23617.889122045224 14989.5063704612 17968.628302569643 16740.266661958613 17411.064026140204 0.7089797367474335 0.2059575293128772 0.46855779238645806 0.8812950791740132 0.7750988489095718 1.3564874086147962 0.8609184566754 1.0320235613166626 0.9614729253091893 1.0 14.087716751310973 -5.88803023166675 2.1109484059517896 1.0118934564097255 0.4217333209725748 0.6333994785531056 0.18217287766511514 0.186636134357258 1.6924039741558419 0.05492008028017839 0.09464793678998715 1.2941057543379892e-06 5.88803023166675 -0.5901601354371506 TTPESPPY(ph)SSGSYDSIKTEVSGCPEDLTVGR ddPTM_PC-9_AZD4547_30min_R2 1 TTPESPPYSSGSYDSIKTEVSGCPEDLTVGR 31 1 A0A087WTU5;A0A087X0N3;Q96MY1-2;Q96MY1 A0A087WTU5 NOL4L Nucleolar protein 4-like 1 T(0.013)T(0.01)PES(0.131)PPY(0.399)S(0.105)S(0.105)GS(0.105)Y(0.091)DS(0.034)IKT(0.004)EVS(0.003)GCPEDLTVGR 68.461 0.00035563 10416000.0 34520.0 17317.0 36572.0 87986.0 69900.0 40351.0 24506.0 34187.0 28228.0 46801.0 True False 45496.64193939511 22914.381597608095 36087.031384279704 67702.187070149 60195.59156182721 37827.84559119378 26686.986525587483 28904.184689106867 29720.07445139585 45162.51123511575 1.0073984084396874 0.5073761615760463 0.7990483787850247 1.4990793297053797 1.3328663512188093 0.8375939370213993 0.5909101552536615 0.6400039302206173 0.6580695722758491 1.0 15.462838088107667 -6.99554153217806 24.604317038295637 0.6953898893354569 1.0206635236961097 0.2184016354564008 0.2733622478852812 172.72698771477351 953193.902176969 0.1080020704277704 0.09486862475839497 1.0103188777256647e-07 6.99554153217806 0.3252736343606528 TTPESPPYS(ph)SGSYDSIKTEVSGCPEDLTVGR ddPTM_PC-9_Lapatinib_30min_R1 1 TTPESPPYSSGSYDSIKTEVSGCPEDLTVGR 31 1 A0A087WTU5;A0A087X0N3;Q96MY1-2;Q96MY1 A0A087WTU5 NOL4L Nucleolar protein 4-like 1 T(0.016)T(0.016)PES(0.016)PPY(0.158)S(0.174)S(0.174)GS(0.174)Y(0.144)DS(0.05)IKT(0.027)EVS(0.036)GCPEDLT(0.015)VGR 53.073 0.009734399999999999 8592700.0 83470.0 39185.0 48895.0 37855.0 32802.0 39087.0 20279.0 22795.0 48701.0 26155.0 True False 82279.70249347661 39094.26954001922 44875.04184015812 40638.98298057809 30872.65085121327 37415.3401262473 21328.947394090937 23854.13891723879 43215.78053573462 30675.856900653187 2.682229962147353 1.2744312136619327 1.462878184152782 1.3247872133512513 1.0064152715015402 1.2196999173460938 0.6953007853429116 0.77761931783985 1.4087880470851466 1.0 14.904816024303353 -2.1643513242550467 0.891908157725257 1.0394418052854386 199.99999999999977 0.788721056698482 0.24188246923411896 104.62561859166549 0.8764198163947406 0.08220888143985271 41533.728171002454 0.0068493392224860394 2.1643513242550467 198.96055819471434 up TTPESPPYSSGS(ph)YDSIKTEVSGCPEDLTVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTPESPPYSSGSYDSIKTEVSGCPEDLTVGR 31 1 A0A087WTU5;A0A087X0N3;Q96MY1-2;Q96MY1 A0A087WTU5 NOL4L Nucleolar protein 4-like 1 T(0.053)T(0.053)PES(0.051)PPY(0.081)S(0.093)S(0.093)GS(0.292)Y(0.253)DS(0.031)IKT(0.001)EVSGCPEDLTVGR 68.461 5.2833999999999996e-05 7000600.0 27702.0 7475.6 19339.0 40505.0 41138.0 64638.0 43012.0 49584.0 46468.0 40836.0 True False 32391.401460560057 8217.728163480744 19800.11510356592 38235.63616898181 33077.30421160395 61248.26949130429 38937.591980086814 48282.47253859067 47147.50659118087 48239.243542401884 0.6714740755022058 0.17035358683138202 0.41045658367676907 0.7926251193257832 0.6856928463757788 1.2696772377342025 0.8071766702946119 1.0008961375223637 0.9773682821070486 1.0 15.557919663524963 -6.045100897997314 1.5963716621665407 0.9845717876433431 0.3858093706475268 0.6472056255607923 0.17875419799938666 0.22237132475034435 1.139198352679232 0.05934978368678966 0.09695905269760673 9.013617033168933e-07 6.045100897997314 -0.5987624169958163 TTPPESAPQNGPS(ph)PMAALMSVADTLGTAHSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTPPESAPQNGPSPMAALMSVADTLGTAHSPK 32 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 T(0.197)T(0.085)PPES(0.069)APQNGPS(0.569)PMAALMS(0.069)VADT(0.005)LGT(0.005)AHS(0.001)PK 48.533 0.0058243 5427400.0 6408.1 9054.8 6603.9 9037.1 9940.6 6487.4 9181.3 7304.1 6630.7 7686.9 True False 7492.864764255823 9953.700702911538 6761.362021430217 8530.780585673509 7992.810789194182 6147.1893235849975 8311.580797144306 7112.375114333656 6727.661443448029 9080.474120533076 0.8251622839068175 1.0961653070960131 0.7446045142225775 0.9394642253738071 0.8802195439465619 0.6769678809705283 0.915324539976374 0.7832603253888376 0.7408931906138263 1.0 13.148551911857169 -5.275501990192696 24.992059949711635 0.8299085453454899 0.9606638188933827 0.16321132705269625 0.11324724791303431 1128.605340570409 2005756.262965205 0.02805584839326351 0.058854490594314295 5.302711626093619e-06 5.275501990192696 0.13075527354789285 TTPPESAPQNGPSPMAALMS(ph)VADTLGTAHSPK ddPTM_PC-9_AZD4547_30min_R2 1 TTPPESAPQNGPSPMAALMSVADTLGTAHSPK 32 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 TTPPESAPQNGPS(0.043)PMAALMS(0.379)VADT(0.148)LGT(0.187)AHS(0.243)PK 52.96 0.0026024 3163900.0 5445.9 6443.6 7111.2 6783.5 7612.3 8178.0 7568.1 7916.3 6182.8 5389.3 True False 7177.582918243098 8526.367688534245 7016.900841624462 5219.668879030258 6555.463542862618 7666.628367197414 8241.646238647621 6693.017733476957 6509.610185563632 5200.622247375253 1.3801392558103243 1.6394899077389231 1.3492425536513217 1.0036623755291239 1.2605152289557564 1.474175204912595 1.5847423340172744 1.286964792887027 1.251698330685145 1.0 12.344468534741829 -8.61582418361902 1.8888449466334951 1.0025265904300675 1.376231447591401 0.3166214423516551 0.16781031569058144 0.6225057294078593 4.829395588882978 0.17789157788057822 0.049948587824959735 2.422009355614944e-09 8.61582418361902 0.3737048571613335 TTPPESAPQNGPSPMAALMS(ph)VADTLGTAHSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTPPESAPQNGPSPMAALMSVADTLGTAHSPK 32 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 TTPPES(0.001)APQNGPS(0.234)PMAALMS(0.754)VADT(0.01)LGT(0.001)AHSPK 89.024 9.9723e-10 12581000.0 27214.0 33765.0 29322.0 32897.0 33945.0 27020.0 33599.0 27615.0 24579.0 26409.0 True False 31820.792698999376 37116.966054888886 30021.147684304247 31053.887743513023 27293.72092622138 25603.0236340085 30416.259484305243 26890.13551051108 24938.421376100407 31196.74264647102 1.0200036926803622 1.189770562763788 0.9623167400683816 0.9954208391376991 0.8748900882223629 0.8206954143946409 0.9749819020847658 0.8619533076012632 0.7993918358307015 1.0 14.929107780011579 -5.731111696301717 1.5315650491175883 0.8843822149897734 1.1015917128153299 0.5166175830768596 0.07632816861624168 0.2972350344783728 1.4023530398514887 0.023807762500334707 0.05589986049004794 1.8573267073580256e-06 5.731111696301717 0.21720949782555643 TTPPESAPQNGPSPMAALMSVADTLGT(ph)AHSPK ddPTM_PC-9_Lapatinib_30min_R1 1 TTPPESAPQNGPSPMAALMSVADTLGTAHSPK 32 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 TTPPESAPQNGPSPMAALMS(0.001)VADT(0.045)LGT(0.68)AHS(0.275)PK 87.12 2.7316e-09 1099000.0 2386.3 2581.1 2854.3 2792.7 2358.1 2864.6 2765.3 2167.1 2041.2 2361.2 True False 2352.2709244061743 2575.1236215323106 2619.6304719166246 2998.0844741741 2219.401194202976 2742.08773570875 2908.473703283183 2267.7913773875043 1811.298561211093 2769.3302738987663 0.8494006462777586 0.9298723398227816 0.945943680537826 1.0826027153320665 0.8014216343644778 0.9901627702384291 1.0502444329937308 0.8188952393153248 0.6540565342757328 1.0 11.435321406298197 -7.8968091879903435 8.11150628258529 0.7973766934566807 0.9497029506430364 0.20270551225134215 0.1111276400873226 0.3131699009422027 21.77855695398479 0.05872896794464311 0.028094011363843343 1.268208944878976e-08 7.8968091879903435 0.15232625718635573 TTPPESAPQNGPSPMAALMSVADTLGTAHS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 TTPPESAPQNGPSPMAALMSVADTLGTAHSPK 32 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 TTPPESAPQNGPSPMAALMS(0.01)VADT(0.065)LGT(0.437)AHS(0.487)PK;TTPPESAPQNGPS(0.027)PMAALMS(0.005)VADT(0.04)LGT(0.133)AHS(0.794)PK;TTPPESAPQNGPS(0.019)PMAALMS(0.019)VADT(0.033)LGT(0.113)AHS(0.816)PK 92.334 4.2843e-10 7717700.0 14005.46 13767.800000000001 15697.599999999999 18977.0 19343.0 20719.3 18971.7 19047.7 22100.7 20984.7 True False 18458.904948334894 18217.972105996927 15489.439567370371 14602.145841727308 16657.558334483892 19423.718895631355 20660.14454694721 16104.315637602034 23268.897882526704 20250.03204024558 0.9115494193613649 0.8996515200464834 0.7649093856536202 0.7210924808764018 0.8225941717710922 0.9591944771755431 1.020252437422645 0.7952735879921468 1.1490795588017506 1.0 14.305636570226556 -6.778767324047083 5.331686239768428 0.9755982651574404 0.8185267389825477 0.4091646388271304 0.09636329806195246 0.19488396971854027 15.78364150924984 0.03393173060947731 0.031165240138971845 1.664304072749838e-07 6.778767324047083 -0.15707152617489273 TTPPESAPQNGPSPMAALMSVADTLGTAHS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TTPPESAPQNGPSPMAALMSVADTLGTAHSPK 32 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 TTPPESAPQNGPS(0.002)PMAALMS(0.021)VADT(0.009)LGT(0.114)AHS(0.855)PK;TTPPESAPQNGPS(0.006)PMAALMS(0.223)VADT(0.223)LGT(0.104)AHS(0.445)PK;TTPPESAPQNGPSPMAALMS(0.004)VADT(0.028)LGT(0.027)AHS(0.941)PK 119.02 6.4170000000000006e-18 48642000.0 69195.0 81394.0 74275.0 89837.0 89747.0 71138.0 83427.0 66220.0 73731.0 70341.0 True False 80908.34683645413 89474.25840579365 76045.99768950626 84803.72414548394 72161.71960423022 67407.39804870829 75524.19060082531 64481.795165889744 74809.17638965203 83093.26648095055 0.9737052141884768 1.0767931289150363 0.9151884491981079 1.0205847926910603 0.8684424461851379 0.8112257575547556 0.9089086733416543 0.7760170937638183 0.9003037136204329 1.0 16.34244395151334 -6.2694610101650445 23.32860263024827 0.8645422105541467 0.996485453001869 0.4155831019579804 0.06815341390298536 205.7226642305319 598284.0253152899 0.019756196073791213 0.022840289691725416 5.376987041538938e-07 6.2694610101650445 0.13194324244772226 TTPPESAPQNGPSPMAALMSVADTLGTAHS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 TTPPESAPQNGPSPMAALMSVADTLGTAHSPK 32 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 TTPPESAPQNGPS(0.001)PMAALMS(0.012)VADT(0.046)LGT(0.222)AHS(0.719)PK;TTPPESAPQNGPSPMAALMSVADT(0.001)LGT(0.049)AHS(0.95)PK 88.742 4.939899999999999e-07 2569400.0 6857.9 8838.7 6569.200000000001 7749.1 6418.6 10654.8 6132.1 6869.6 6029.67 7427.0 True False 6760.105088415167 8818.234533198112 6029.105733845317 8318.99466423981 6041.070567453128 10199.119041551914 6449.590133404262 7188.78669470777 5350.545069360029 8710.747054144567 0.776064905385895 1.0123396395722917 0.6921456559775402 0.9550265450862379 0.6935192274443087 1.1708661700490064 0.7404175661759748 0.8252778607877668 0.6142464057447568 1.0 13.088580737710362 TTPPTQKPPS(ph)PPMSGK ddPTM_PC-9_AZD4547_30min_R2 2 TTPPTQKPPSPPMSGK 16 1 H0Y6B5;B7Z836;E7EW77;E7EP65;A0A0C4DG21;F8WAL6;Q9NYB9-3;Q9NYB9-2;Q9NYB9-4;Q9NYB9;H7C3Q7;E9PEZ7 H0Y6B5 ABI2 Abl interactor 2 1 TTPPT(0.001)QKPPS(0.998)PPMS(0.002)GK;TTPPTQKPPS(0.993)PPMS(0.007)GK 131.48 4.7307e-06 63601000.0 312990.0 288230.0 282190.0 397060.0 364070.0 358840.0 342860.0 326360.0 286280.0 344570.0 True False 412514.3094035706 381394.7108551471 278447.97622032964 305523.9515158482 313525.16480564274 336401.678073505 373373.8757921699 275928.5610067247 301412.1763477966 332506.70917894563 1.2406195063618015 1.1470286172478141 0.8374206250090337 0.918850486566946 0.942913800385641 1.0117139558001014 1.1229062917681782 0.8298435892859769 0.9064844949807769 1.0 18.34302392543121 -5.085783911802436 4.967323181558897 0.9483532097297906 1.2212859322771135 0.6027725407021147 0.08182573350975919 0.13872864729202336 5.693418996501407 0.022202689903657407 0.0652423118663484 8.207598212069613e-06 5.085783911802436 0.2729327225473228 TTPPTQKPPS(ph)PPMSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTPPTQKPPSPPMSGK 16 1 H0Y6B5;B7Z836;E7EW77;E7EP65;A0A0C4DG21;F8WAL6;Q9NYB9-3;Q9NYB9-2;Q9NYB9-4;Q9NYB9;H7C3Q7;E9PEZ7 H0Y6B5 ABI2 Abl interactor 2 1 TTPPTQKPPS(0.946)PPMS(0.054)GK;TTPPT(0.001)QKPPS(0.676)PPMS(0.322)GK 67.928 0.013756 40896300.0 103441.0 110689.0 89537.0 122426.0 123569.0 100659.0 117025.0 122007.0 88731.0 88109.0 True False 120951.51824712273 121677.47240188353 91671.90165096348 115566.868130447 99356.5414974886 95380.26483995785 105939.54481237002 118804.4455271023 90028.52301244024 104082.46422953981 1.1620739299598106 1.1690487278773523 0.8807622141688872 1.110339469630349 0.9545944384864983 0.9163913013205526 1.0178423963784589 1.1414453568767853 0.8649730161451069 1.0 16.667367498884666 -5.234973563404118 24.264730884711184 0.9928449141839645 1.1655614388660411 0.41338522155329405 0.0853284650957179 504.7596305057412 462777.54989141115 0.02094754997376829 0.05537835424517843 5.821386529342428e-06 5.234973563404118 0.17271652468207666 TTPPTQKPPS(ph)PPMSGK ddPTM_PC-9_Lapatinib_30min_R1 2 TTPPTQKPPSPPMSGK 16 1 H0Y6B5;B7Z836;E7EW77;E7EP65;A0A0C4DG21;F8WAL6;Q9NYB9-3;Q9NYB9-2;Q9NYB9-4;Q9NYB9;H7C3Q7;E9PEZ7 H0Y6B5 ABI2 Abl interactor 2 1 TTPPTQKPPS(0.998)PPMS(0.002)GK;TTPPT(0.001)QKPPS(0.998)PPMS(0.001)GK 99.273 0.00091349 94805000.0 194141.0 163485.0 133616.0 155781.0 154065.0 159881.0 143337.0 145454.0 138643.0 139427.0 True False 191372.51373890077 163106.4605269882 122630.60825267529 167237.65441018177 145003.19960344402 153043.26233081438 150758.28850667275 152212.32384593293 123027.5653644864 163526.7711752005 1.1702824703477248 0.997429713525243 0.7499115121724651 1.0226928178689805 0.8867245317776711 0.935891176906109 0.921918089761292 0.9308098163502206 0.7523389869459126 1.0 17.3191673149311 -4.877031961744238 3.7470543265091507 0.901932117230435 1.1743345076807175 0.48094439176910053 0.08563443453104194 0.1916808609011471 4.542843179946425 0.02040054061101827 0.12014643710554494 1.327296772212632e-05 4.877031961744238 0.27240239045028247 TTPQQGASGPGRS(ph)PVGQAR ddPTM_PC-9_AZD4547_30min_R2 2 TTPQQGASGPGRSPVGQAR 19 1 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 TTPQQGAS(0.036)GPGRS(0.963)PVGQAR;TTPQQGAS(0.021)GPGRS(0.979)PVGQAR 88.28299999999999 0.0054319 12568100.0 7407.3 3869.3999999999996 7185.9 16026.800000000001 13038.099999999999 8929.7 7248.0 10678.099999999999 8441.7 9256.599999999999 True False 9762.667318588688 5120.107879758895 7090.610270816346 12332.068871591675 11227.984868987978 8371.324447366436 7893.05795876349 9028.04500332735 8887.911027927881 8932.529251489763 1.092934267969005 0.5731979975218068 0.7937964792708379 1.3805797355250684 1.2569771173282618 0.9371729116890685 0.8836307989080573 1.0106930242430112 0.9950049731374302 1.0 13.12485301789582 -5.62161895868573 23.72623036134695 1.0636630423278173 0.7950601115883721 0.27208243906632334 0.1832344324252982 11.173384094576495 2667.1813599241214 0.052165010448074936 0.09035240545036063 2.389907220228438e-06 5.62161895868573 -0.2686029307394452 TTPQQGASGPGRS(ph)PVGQAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TTPQQGASGPGRSPVGQAR 19 1 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 T(0.001)TPQQGAS(0.025)GPGRS(0.973)PVGQAR;TTPQQGAS(0.019)GPGRS(0.981)PVGQAR;TTPQQGAS(0.045)GPGRS(0.954)PVGQAR 72.99 0.0024579999999999997 35517100.0 18023.5 15495.699999999999 40556.6 24808.0 36051.0 37552.9 30595.6 31655.300000000003 28544.1 26154.7 True False 21074.52256964854 17034.010688486364 41523.623155762034 23418.08818862116 28987.065344268878 35583.55981589776 27697.363275038217 30824.38191656279 28961.503462368193 30896.340069508704 0.6821041755184064 0.5513277834903514 1.3439657597742878 0.7579567073619908 0.9382038545360242 1.1517079283774077 0.8964609792851314 0.9976709813271077 0.937376511172921 1.0 14.91514832847854 -5.227021867803564 24.99829279541026 0.9932867997598289 0.6167158119030401 0.5110596311465314 0.15086557103317677 478.3542978212396 347439.1753582106 0.03631237942488059 0.09606397236654424 5.9289547007197085e-06 5.227021867803564 -0.3765709878567888 TTPQQGASGPGRS(ph)PVGQAR ddPTM_PC-9_Lapatinib_30min_R1 1 TTPQQGASGPGRSPVGQAR 19 1 A0A2R8YF49;A0A2R8YFR7;Q12774;H0Y895 A0A2R8YF49 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 TTPQQGAS(0.032)GPGRS(0.967)PVGQAR 48.053000000000004 0.035431 12050000.0 4035.8 2700.2 4349.1 2254.2 3473.6 3145.9 3328.0 2509.8 3094.9 2263.7 True False 3978.248751924921 2693.947852799793 3991.5337860114896 2419.9813877907595 3269.289677360359 3011.357190451078 3500.307555970939 2626.414470475362 2746.3197712581878 2654.9775288093515 1.4984114587625164 1.0146782123643503 1.5034152804304632 0.9114884632850441 1.2313812986682795 1.1342307638293077 1.318394418780894 0.9892416948828946 1.0344041489834377 1.0 11.374483935065337 -1.5228787452803376 0.1697516815774903 0.9860327879846563 2.40520643978767 0.2449640506393359 0.17735214499261706 94.85424896071486 1.0256126698561168 0.4398676403797643 34.16478670582231 0.029999999999999995 1.5228787452803376 1.4191736518030136 TTPS(ph)YVAFTDTER ddPTM_PC-9_AZD4547_30min_R2 2 TTPSYVAFTDTER 13 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;P11142;E9PKE3;P11142-2;E9PNE6;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65;E9PPY6;P54652;E9PN25;P17066;P48741 A0A0G2JIW1;P11142;P17066 HSPA1B;HSPA1A;HSPA8;HSPA2;HSPA6;HSPA7 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2;Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7 1 T(0.041)T(0.219)PS(0.74)YVAFTDTER;TTPS(1)YVAFTDTER 168.0 9.886299999999999e-05 8128600.0 12636.599999999999 15318.3 17122.9 25927.0 24863.0 26866.0 11520.6 18846.0 17515.3 16501.2 True False 16654.77594239167 20269.640909316862 16895.839158095903 19949.930718156917 21411.201616619608 25186.06477294273 12545.911081640541 15933.783737997142 18441.122999806346 15923.498010574387 1.045924452738441 1.272938954484518 1.0610632881591602 1.2528610676440992 1.3446292769591819 1.581691708456101 0.7878866234861914 1.0006459464758262 1.1581075331287176 1.0 13.9588696757428 -7.279469780202902 24.99956288074042 0.986713880570056 1.2549463404476893 0.40249251967866784 0.1630009896070364 941.0638815150695 1304801.1911861482 0.07107494823346297 0.048020583179251106 5.2544857647013173e-08 7.279469780202902 0.2682324598776332 TTPS(ph)YVAFTDTER ddPTM_PC-9_Lapatinib_30min_R1 1 TTPSYVAFTDTER 13 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;P11142;E9PKE3;P11142-2;E9PNE6;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65;E9PPY6;P54652;E9PN25;P17066;P48741 A0A0G2JIW1;P11142;P17066 HSPA1B;HSPA1A;HSPA8;HSPA2;HSPA6;HSPA7 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2;Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7 1 TT(0.001)PS(0.999)YVAFTDTER 128.68 0.00010202 2662500.0 3972.6 4985.6 4802.7 4831.6 4226.2 3704.5 4679.7 3259.2 5332.5 2584.0 True False 3915.9499955143838 4974.056149514352 4407.840544958121 5186.931981745111 3977.623225028886 3546.0671706112807 4921.991968052045 3410.6343302945647 4731.897696285595 3030.640957036427 1.2921194067619524 1.64125550338313 1.454425188415726 1.711496695015056 1.3124693031663124 1.1700716847959691 1.6240762392603292 1.125383830894215 1.56135212430864 1.0 11.565407229431917 -6.307707264775308 23.48267449030228 1.314979389370726 1.5281122425668716 0.22355218324243364 0.20492854645641112 325.3417942605399 165121.8777590146 0.059339913275940716 0.06728552765620152 4.923713056323925e-07 6.307707264775308 0.2131328531961456 TTPSYVAFTDTER ddPTM_PC-9_AZD4547_30min_R2 3 TTPSYVAFTDTER 13 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;P11142;E9PKE3;P11142-2;E9PNE6;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65;E9PPY6;P54652;E9PN25;P17066;P48741 A0A0G2JIW1;P11142;P17066 HSPA1B;HSPA1A;HSPA8;HSPA2;HSPA6;HSPA7 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2;Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7 0 ;; 182.92 0.0002878 54646000.0 107649.0 90849.0 137739.0 220286.0 170511.0 147110.0 133137.0 140258.0 108749.0 165516.0 False True 141879.14276170166 120214.1626009758 135912.49086293607 169502.46608477327 146838.49088410166 137911.18844441313 144985.93507945605 118584.34890820336 114497.2501245163 159721.33521914942 0.8882917399045847 0.7526493717075 0.8509351031686164 1.0612387246337718 0.9193417440608573 0.8634487575200197 0.9077430693934826 0.7424452640938477 0.7168563296031657 1.0 17.285197512038778 -7.746329893000514 24.962597122743123 0.7972380891750198 0.8914830591595597 0.08441170432303724 0.10106849293956308 445.0030604110596 735198.3951310115 0.04907185291496005 0.028192223015061885 1.7933708527870962e-08 7.746329893000514 0.0942449699845399 TTPSYVAFTDTER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TTPSYVAFTDTER 13 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;P11142;E9PKE3;P11142-2;E9PNE6;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65;E9PPY6;P54652;E9PN25;P17066;P48741 A0A0G2JIW1;P11142;P17066 HSPA1B;HSPA1A;HSPA8;HSPA2;HSPA6;HSPA7 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2;Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7 0 ;;; 187.31 0.00016149 52372300.0 93902.0 109788.0 95263.0 127286.0 121341.0 106766.0 99263.0 98396.0 105436.0 84667.0 False True 109797.75395096051 120687.02707638517 97534.43120693919 120154.57808677957 97565.10210365668 101167.0030091987 89860.09003811402 95813.20925917971 106977.80203468491 100016.45687639684 1.0977968764345618 1.206671690295264 0.9751838272722957 1.2013480764997504 0.9754904857730602 1.0115035682000186 0.8984530430743578 0.9579744399223058 1.0696019972682205 1.0 16.60987787744245 -6.285552741516861 24.556183248678316 0.9803500640190611 1.1160612079589505 0.45358102836490677 0.07226209957619874 555.4348449236519 565633.0532423698 0.02174174014387167 0.024665582260097147 5.181401642962651e-07 6.285552741516861 0.13571114393988937 TTPSYVAFTDTER ddPTM_PC-9_Lapatinib_30min_R1 4 TTPSYVAFTDTER 13 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;P11142;E9PKE3;P11142-2;E9PNE6;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65;E9PPY6;P54652;E9PN25;P17066;P48741 A0A0G2JIW1;P11142;P17066 HSPA1B;HSPA1A;HSPA8;HSPA2;HSPA6;HSPA7 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2;Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7 0 ;;; 229.68 3.5193e-19 233878000.0 188823.0 188930.0 187285.0 205088.0 152483.0 169640.0 184834.0 159740.0 172122.0 161062.0 False True 186130.3493941029 188492.54419282466 171887.15024100695 220170.85567351233 143514.2497331124 162384.89265015445 194403.8001202923 167162.10355954058 152735.80783498732 188901.35209837536 0.9853309535718443 0.9978358656462247 0.9099307566178361 1.165533508510053 0.7597311937628354 0.8596280060800636 1.0291286852147643 0.8849174540184684 0.808547986228527 1.0 17.527273502571987 -6.270414183620867 24.99708941307986 0.8899767154431012 1.005975708847577 0.28752247391769414 0.09549103436445683 936.8155991122971 2609263.6779901935 0.029505263505985552 0.03393887711164935 5.365198770342899e-07 6.270414183620867 0.11599899340447573 TTPTPS(ph)TNSVLSTSTNR ddPTM_PC-9_AZD4547_30min_R2 1 TTPTPSTNSVLSTSTNR 17 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 TTPTPS(0.841)T(0.151)NS(0.008)VLSTSTNR 170.48 2.5026999999999998e-24 0.0 11951.0 10472.0 17461.0 18448.0 16019.0 19914.0 13115.0 21749.0 17364.0 19009.0 True False 15751.169403757569 13856.869208878674 17229.45573118528 14195.098618758777 13795.038358067382 18668.77443193559 14282.209592878475 18388.19179230073 18281.82559069142 18343.500695889295 0.8586784859057651 0.7554102915581399 0.9392675922020889 0.7738489426906305 0.7520395690424999 1.0177323697062464 0.778597816723122 1.002436345011367 0.9966377679909432 1.0 14.162981370426406 -7.728163553864415 1.001354267184129 1.0177587995039337 0.8280504869969182 0.3881711852984384 0.08526360185772731 0.5508677846763665 1.0014403646396666 0.07208240516084305 0.02986335284841411 1.8699777803016616e-08 7.728163553864415 -0.18970831250701548 TTPTPS(ph)TNSVLSTSTNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTPTPSTNSVLSTSTNR 17 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 T(0.001)T(0.001)PT(0.002)PS(0.563)T(0.42)NS(0.013)VLSTSTNR 94.454 0.013000000000000001 0.0 2346.1 2633.3 3215.7 4259.0 3911.4 2554.4 3089.3 2892.6 3076.5 3237.5 True False 2743.2483924128173 2894.7166211265803 3292.3744836101614 4020.3820378642995 3144.9892482198366 2420.4427672358 2796.659139404869 2816.6723149630407 3121.4879923338194 3824.4331219641003 0.7172954278264323 0.7569008344012959 0.8608790841972701 1.0512360681050599 0.8223412850803561 0.6328892910520402 0.7312610915702453 0.7364940698757708 0.8161962551800953 1.0 11.901030204300076 -5.051585481637568 5.167901679234402 0.8186873421902953 0.7251743698012889 0.09000071323901826 0.11737481001943244 0.5422698336154648 32.472510149096514 0.03265437738520561 0.09876678040200461 8.880031745669437e-06 5.051585481637568 -0.09351297238900635 TTPTPSTNS(ph)VLSTSTNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTPTPSTNSVLSTSTNR 17 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 T(0.001)TPT(0.011)PS(0.178)T(0.178)NS(0.613)VLS(0.008)T(0.008)S(0.001)T(0.001)NR 109.14 0.0036303000000000004 0.0 2164.2 2042.1 3774.0 3619.1 6852.4 4330.7 4333.7 4170.4 4135.9 4150.6 True False 2530.5563151015836 2244.826192231263 3863.986472974705 3416.333560280512 5509.721410364984 4103.590468238362 3923.180562729058 4060.931418904053 4196.379713145927 4903.070923868481 0.5161166041434694 0.4578408566972379 0.7880747664009013 0.696774248899719 1.1237286786008513 0.8369429143400323 0.8001476265886242 0.8282424386592419 0.8558676344487831 1.0 12.259469915299205 -5.441973099154515 1.6832492782777098 0.8827718962816914 0.4652866289289169 0.6614793182586409 0.11002770803123092 0.2509223133633582 1.3195493373286502 0.03282170807679503 0.1097810844834281 3.6143224959682267e-06 5.441973099154515 -0.41748526735277447 TTPTPSTNSVLSTS(ph)TNR ddPTM_PC-9_AZD4547_30min_R2 1 TTPTPSTNSVLSTSTNR 17 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 TTPTPSTNSVLS(0.007)T(0.093)S(0.705)T(0.195)NR 152.25 4.8334e-12 0.0 7123.2 6820.9 10100.0 16152.0 16868.0 12905.0 12431.0 13839.0 9720.4 12965.0 True False 9388.229428235783 9025.622535030612 9966.06740077723 12428.40594591239 14526.169362874118 12098.048309939182 13537.334917962047 11700.500538583388 10234.200499410097 12511.099296238874 0.7503920483676525 0.7214092320203968 0.7965780755791189 0.9933904009257328 1.1610625908181402 0.9669852363473876 1.0820260152544456 0.9352096295887309 0.8180096933997426 1.0 13.610920938002423 -5.699163625852925 3.8923297027295147 1.0016013353745248 0.7416037549478551 0.6259926029367725 0.08482117503431895 0.14518693841092453 4.386666530029312 0.02513365722472655 0.044435758902048164 1.99910853869785e-06 5.699163625852925 -0.25999758042666965 TTPVDLCLLEESVGS(ph)LEGSR ddPTM_PC-9_AZD4547_30min_R2 2 TTPVDLCLLEESVGSLEGSR 20 0 Q9UKK3 Q9UKK3 PARP4 Poly [ADP-ribose] polymerase 4 1 TTPVDLCLLEES(0.003)VGS(0.955)LEGS(0.042)R;TTPVDLCLLEES(0.005)VGS(0.983)LEGS(0.012)R 174.7 2.899e-09 4211000.0 13022.9 9531.400000000001 15504.3 20416.6 18596.7 15745.900000000001 13327.0 18499.0 15020.5 14155.2 True False 17163.911306852515 12612.238653314194 15298.70285167035 15709.8683033256 16014.869207408183 14761.306383841247 14513.077182180057 15640.404614730402 15814.452965041497 13659.63075650756 1.2565428460557388 0.9233220778904012 1.1199938800967897 1.1500946536085017 1.172423288219454 1.0806519332016966 1.062479465286125 1.145009326645172 1.1577511315602262 1.0 13.737630865157296 TTPVDLCLLEESVGS(ph)LEGSR ddPTM_PC-9_Lapatinib_30min_R1 2 TTPVDLCLLEESVGSLEGSR 20 0 Q9UKK3 Q9UKK3 PARP4 Poly [ADP-ribose] polymerase 4 1 TTPVDLCLLEES(0.094)VGS(0.905)LEGS(0.001)R;TTPVDLCLLEESVGS(1)LEGSR 210.61 1.3817999999999998e-21 5958700.0 11893.8 15552.4 17072.0 13998.6 16661.2 19280.7 16888.5 19110.6 17400.7 17330.7 True False 11724.192230944205 15516.389373336604 15668.406059825744 15028.10374196066 15681.220973179521 18456.10940650693 17762.903893934857 19998.54824267529 15440.849928505717 20326.28840329382 0.57679946276096 0.7633656015046119 0.7708444231897605 0.7393432309818745 0.7714748832668546 0.9079921056082313 0.8738882151773674 0.9838760449465324 0.7596492592323727 1.0 14.311059181499507 -3.1785867433264925 0.2142869100634984 0.9778491939582442 9.709375958230183e-15 0.6554367824597562 0.07114421844797328 16.093210966867584 0.37281624768565036 0.1209233728045088 4.672306849223088 0.0006628469414496827 3.1785867433264925 -0.9778491939582346 TTQSMQDFPVVDS(ph)EEEAEEEFQK ddPTM_PC-9_AZD4547_30min_R2 1 TTQSMQDFPVVDSEEEAEEEFQK 23 0 Q9UBB9 Q9UBB9 TFIP11 Tuftelin-interacting protein 11 1 TTQSMQDFPVVDS(1)EEEAEEEFQK 90.53399999999999 0.00050429 0.0 4278.6 4244.5 5148.5 6591.7 4557.0 5409.8 3910.7 6492.8 4810.1 5333.5 True False 5639.105799591427 5616.4516192786 5080.227526029862 5072.085405749798 3924.339209545733 5071.5243508027115 4258.744723970252 5489.486949701144 5064.352065986224 5146.775788391055 1.0956579480906978 1.0912563224430594 0.987069912291245 0.9854879276439966 0.7624849752338889 0.9853789166883704 0.8274587623529619 1.0665875443968436 0.9839853675789134 1.0 12.329453219718298 -5.41470811602948 2.084729616323591 0.9363552898555435 1.1008142537121721 0.33049957697458543 0.08357860738097113 0.3879356921342491 3.2030829055381393 0.024253395394723112 0.07156538795028439 3.8485034832353774e-06 5.41470811602948 0.16445896385662861 TTQSMQDFPVVDS(ph)EEEAEEEFQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTQSMQDFPVVDSEEEAEEEFQK 23 0 Q9UBB9 Q9UBB9 TFIP11 Tuftelin-interacting protein 11 1 TTQSMQDFPVVDS(1)EEEAEEEFQK 76.51 0.0020071 0.0 4874.9 6722.0 6473.6 6992.5 7431.5 6729.4 7425.3 6727.2 6247.8 4638.7 True False 5700.124286336152 7389.3157358496455 6627.955175264714 6600.732894990871 5975.3509224691215 6376.4984175683485 6721.921829483365 6550.618128057578 6339.1622553236575 5479.659590071007 1.0402332832252246 1.3484990471376876 1.2095560073246863 1.2045881293340224 1.0904602419639886 1.1636668871041531 1.2267042722258337 1.1954425307599617 1.1568532955605573 1.0 12.419870556867867 -8.75364532954539 2.914687427376615 1.0000197827414903 1.189105007753149 0.33506791445314643 0.07751124490342749 1.6071895262061215 18.83593472565535 0.07302836102216828 0.01945555165719611 1.7634155675534012e-09 8.75364532954539 0.1890852250116588 TTRT(ph)PDTSTYCYETAEK ddPTM_PC-9_AZD4547_30min_R2 1 TTRTPDTSTYCYETAEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.28)T(0.28)RT(0.425)PDT(0.011)S(0.003)T(0.001)YCYETAEK 69.805 0.011229000000000001 117470000.0 39497.0 31638.0 51395.0 106580.0 80249.0 70531.0 48046.0 72681.0 61888.0 64446.0 True False 52056.22441136411 41864.3647851894 50713.46871910355 82009.62764458539 69107.81154857039 66120.68542024962 52322.00092256496 61449.82149322779 65159.2733331439 62189.76515583575 0.8370545262700558 0.673171295634985 0.8154632613907645 1.3186997480869211 1.1112409152116804 1.0632084757767413 0.841328163749388 0.9881018418263231 1.047749146018917 1.0 15.924389548749597 -5.5455650339633795 24.987824917260777 1.0480395890051843 0.7524139269333974 0.5405134239112379 0.11813334985661514 171.1971419788299 188564.33131043488 0.03426442495228642 0.05935223939643925 2.8473113940881463e-06 5.5455650339633795 -0.295625662071787 TTRT(ph)PDTSTYCYETAEK ddPTM_PC-9_Lapatinib_30min_R1 1 TTRTPDTSTYCYETAEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.287)T(0.287)RT(0.425)PDTSTYCYETAEK 114.02 0.00012439 112680000.0 88127.0 64504.0 99418.0 61866.0 66002.0 67829.0 55553.0 52983.0 67959.0 45514.0 True False 86870.29281948759 64354.64495111395 91244.23580457809 66415.83201892607 62119.8921249247 64928.111787121736 58429.262517083414 55444.78360395099 60304.741780004275 53381.03425640715 1.627362489872718 1.2055713391013902 1.7093006359955707 1.2441840617007978 1.1637071666041887 1.216314233914054 1.0945696974777206 1.0386607224137128 1.1297035102456094 1.0 15.704039637485954 -5.961208453656215 6.736308959345879 1.121435414191062 1.4845138081708218 0.6423499077149541 0.13495594584569406 0.12503933417373006 15.628561135234444 0.0367003470099287 0.05431838249678001 1.0934314125939901e-06 5.961208453656215 0.3630783939797597 TTRT(ph)PEEGGYSYDISEK ddPTM_PC-9_AZD4547_30min_R2 4 TTRTPEEGGYSYDISEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.318)T(0.318)RT(0.364)PEEGGYSYDISEK;T(0.05)T(0.011)RT(0.939)PEEGGYSYDISEK;T(0.316)T(0.316)RT(0.368)PEEGGYSYDISEK;T(0.006)T(0.001)RT(0.993)PEEGGYSYDISEK 236.68 2.2521999999999997e-36 167724500.0 167927.0 135764.0 179150.0 250472.0 217230.0 188541.0 157721.0 195331.0 145576.0 188369.0 True False 221324.29290141386 179647.05799027943 176774.35394546948 192729.55015382412 187071.3641627428 176751.50146487693 171757.8634539374 165147.08220984405 153270.85016070565 181774.25864506167 1.2175777502884986 0.9882975693553184 0.9724938792936839 1.0602686628482094 1.0291411201848135 0.9723681602795458 0.94489651468923 0.9085284321379938 0.8431933723904621 1.0 17.471788385990273 -6.950408006924237 1.0897896543518482 0.9066749328195017 1.0554650795618032 0.43076192259062174 0.07120557995927783 0.5021698099278247 1.2389799146269138 0.042473069459641806 0.03193834291231069 1.1209648458769844e-07 6.950408006924237 0.1487901467423015 TTRT(ph)PEEGGYSYDISEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTRTPEEGGYSYDISEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.049)T(0.012)RT(0.939)PEEGGYSYDISEK 131.48 0.00026777 26647000.0 40890.0 29019.0 37509.0 56309.0 56794.0 52180.0 50544.0 56220.0 56127.0 38513.0 True False 47811.86938568696 31899.81454011019 38403.35681367464 53154.189286241104 45665.623399140284 49443.58894235988 45756.10641312908 54744.28457001388 56947.751193148135 45495.10203125977 1.0509234456235603 0.701170304403137 0.8441206877014502 1.16834971047474 1.0037481258479946 1.086789274774834 1.0057369776133258 1.203300621952644 1.251733673528619 1.0 15.473423613749283 -5.75289677571242 24.981551893700264 1.10243959146669 0.848981269971358 0.476215588395842 0.11370505414578769 151.00376315421386 441582.91752952465 0.030877009444614936 0.05241228061312744 1.7664576272223587e-06 5.75289677571242 -0.253458321495332 TTRT(ph)PEEGGYSYDISEK ddPTM_PC-9_Lapatinib_30min_R1 2 TTRTPEEGGYSYDISEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.004)T(0.001)RT(0.994)PEEGGYSYDISEK;T(0.018)T(0.004)RT(0.976)PEEGGY(0.001)SYDISEK 121.51 0.00072976 110413000.0 157323.0 110020.0 143073.0 119916.0 132351.0 123406.0 108835.0 109632.0 129044.0 94369.0 True False 155079.54517049514 109765.2554496088 131310.09021775087 128735.02266804937 124566.37439207768 118128.2130534366 114469.9437662552 114725.90295129312 114509.70582643762 110680.55591121154 1.401145340242966 0.9917302505930942 1.1863880619021143 1.1631222991987968 1.1254585176822332 1.0672896615029617 1.0342371595791722 1.0365497535387043 1.0345964102158816 1.0 16.75604226968754 -1.5228787452803376 0.3268465972199123 1.0255664627720205 3.5437595505692947 0.5029227757211557 0.08283522935112267 54.656905684159206 0.7788707523080398 0.07526414034962609 82.86912391687304 0.029999999999999995 1.5228787452803376 2.5181930877972745 TTRTS(ph)DVGGYYYEK ddPTM_PC-9_AZD4547_30min_R2 1 TTRTSDVGGYYYEK 14 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.001)TRT(0.184)S(0.777)DVGGY(0.032)Y(0.004)Y(0.001)EK 84.759 0.034559 12425000.0 27302.0 15550.0 41403.0 95387.0 81392.0 59915.0 38876.0 64381.0 44578.0 64160.0 True False 35983.46808312181 20576.2334031764 40853.96916776039 73397.00086445922 70092.12572818664 56168.5055784584 42335.88868720881 54432.39577820194 46934.30207220931 61913.77792878413 0.5811867614428492 0.33233690612199535 0.6598526294866446 1.1854712039844115 1.1320925337298846 0.9072052692870044 0.6837878434087055 0.8791645026218947 0.7580590886602842 1.0 15.917972873604048 -5.539674313288387 7.997162475947454 0.9269060340922335 0.4657375760186486 0.6177045630328915 0.1535462038586616 0.10815806420049259 37.586788514366745 0.045495430432015434 0.08100753621082692 2.886195111140866e-06 5.539674313288387 -0.46116845807358486 TTRTS(ph)DVGGYYYEK ddPTM_PC-9_Lapatinib_30min_R1 1 TTRTSDVGGYYYEK 14 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.152)T(0.023)RT(0.265)S(0.559)DVGGY(0.001)YYEK 121.45 0.00034799 12395000.0 79383.0 34709.0 53013.0 38782.0 38372.0 37741.0 28449.0 25142.0 43770.0 22791.0 True False 78250.98386294053 34628.63344301461 48654.475776097854 41634.15765295944 36115.03440225461 36126.905408568025 29921.950017973908 26310.189105383535 38840.161681466554 26730.39398290142 2.9274160310916173 1.2954778543543144 1.8201929910655477 1.5575586981468168 1.351085001790705 1.351529103225237 1.11939801699571 0.9842798846217278 1.4530336405184063 1.0 14.706193481364979 -2.7220533355325456 1.1664812298719025 1.2923386329371933 199.99999999999997 0.7690851463735489 0.2583510935761101 95.24756422710578 1.3526115213008933 0.07885201424732212 49386.34717627865 0.0018964730018141977 2.7220533355325456 198.70766136706277 up TTS(ph)FAESCKPVQQPSAFGSMK ddPTM_PC-9_AZD4547_30min_R2 2 TTSFAESCKPVQQPSAFGSMK 21 1 P49841;P49841-2;A0A3B3ITW1 P49841 GSK3B Glycogen synthase kinase-3 beta 1 T(0.371)T(0.089)S(0.446)FAES(0.094)CKPVQQPSAFGSMK;T(0.132)T(0.132)S(0.729)FAES(0.007)CKPVQQPSAFGSMK 86.182 0.00021399 90444000.0 93937.0 84961.0 124045.0 172275.0 138694.0 136150.0 122543.0 128137.0 122011.0 135790.0 True False 123807.01198901981 112422.98174709141 122400.08225043675 132559.6603722175 119438.73213270497 127636.51897700255 133449.08960275335 108336.3709453324 128460.25236960658 131036.03343125936 0.9448318050161992 0.8579547075962717 0.9340948367049513 1.0116275416849934 0.911495326935104 0.9740566440753857 1.0184152107501014 0.8267677837040522 0.9803429560999034 1.0 16.99960406562129 -5.5147624862448295 24.677843575029556 0.9555605278884229 0.9000511267401052 0.14319156941728195 0.056861316796682174 591.9243860014572 1799767.0543773044 0.014916509573073045 0.02747000137890013 3.056592293167402e-06 5.5147624862448295 -0.055509401148317705 TTS(ph)FAESCKPVQQPSAFGSMK ddPTM_PC-9_Lapatinib_30min_R1 2 TTSFAESCKPVQQPSAFGSMK 21 1 P49841;P49841-2;A0A3B3ITW1 P49841 GSK3B Glycogen synthase kinase-3 beta 1 T(0.138)T(0.164)S(0.684)FAES(0.014)CKPVQQPSAFGSMK;T(0.114)T(0.141)S(0.737)FAES(0.007)CKPVQQPSAFGSMK 107.56 2.991e-05 57248000.0 76710.0 62927.0 77859.0 78813.0 112385.0 184702.0 173434.0 161962.0 215402.0 179469.0 True False 75616.10133310895 62781.29639772339 71457.73356443139 84609.17093246059 105774.73525741136 176802.72602139143 182413.5639009207 169487.3457913502 191141.1584763825 210489.9775225896 0.3592384883265708 0.29826264003940883 0.33948283146527775 0.4019629434535923 0.5025167302612292 0.8399579310250871 0.8666140119728231 0.8052038761473144 0.9080772430405595 1.0 17.683392015459155 -6.640710607697492 1.8587969493177738 0.88674217238183 0.3373368226957988 0.9602841430229655 0.05200475958299753 0.061249046186052834 0.4341702130930236 0.020255074060221725 0.020231420615408547 2.287122320598157e-07 6.640710607697492 -0.5494053496860312 down TTS(ph)FFSR ddPTM_PC-9_AZD4547_30min_R2 2 TTSFFSR 7 0 Q9BZ67-2;Q9BZ67-3;Q9BZ67 Q9BZ67-2 FRMD8 FERM domain-containing protein 8 1 TT(0.006)S(0.993)FFSR;T(0.007)T(0.375)S(0.617)FFSR 126.24 0.0045604999999999995 12428200.0 72526.0 83783.0 95955.0 119836.0 99750.0 104909.0 79097.0 115180.0 86625.0 89267.0 True False 95587.75936548559 110864.21628413693 94682.57400411688 92209.66164774385 85901.43431033277 98349.02364567312 86136.47976880756 97381.5775730932 91203.82065155738 86141.78950076025 1.109656067275477 1.2869969027420598 1.0991479809376523 1.0704405165268833 0.9972097724946223 1.141710942106736 0.9999383605566653 1.130480085652664 1.0587639423343123 1.0 16.394425673840345 -5.460906211487027 6.598862644899138 1.0626594788029449 1.1985189922246262 0.44361451052470746 0.06230342404288613 0.19733105122370573 17.05385353587251 0.015167213716387943 0.031582463608327616 3.460140935887931e-06 5.460906211487027 0.13585951342168134 TTS(ph)FFSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTSFFSR 7 0 Q9BZ67-2;Q9BZ67-3;Q9BZ67 Q9BZ67-2 FRMD8 FERM domain-containing protein 8 1 T(0.016)T(0.356)S(0.629)FFSR;T(0.012)T(0.02)S(0.968)FFSR 109.48 0.0096065 8033800.0 94229.0 99500.0 92468.0 92774.0 110658.0 85731.0 92062.0 80654.0 70667.0 65372.0 True False 110180.10859241613 109377.70242740822 94672.7878068429 87576.17355736598 88975.35926509961 81235.11543920003 83341.22088883923 78536.91795997671 71700.37118617079 77223.42611553273 1.4267705298075928 1.4163798205970557 1.2259594344493918 1.1340622653331216 1.1521809344742748 1.051949123801701 1.0792220065987979 1.0170089817366934 0.9284795403780844 1.0 16.236750942249827 -4.690139148696624 0.40541692805339535 0.9738680358821807 1.872666817478687 0.9349874192162817 0.04087633665032286 1.3876100223625214 0.17000529269780992 0.033674649518647556 0.6181697058342859 2.041083873119801e-05 4.690139148696624 0.8987987815965062 TTS(ph)FFSR ddPTM_PC-9_Lapatinib_30min_R1 2 TTSFFSR 7 0 Q9BZ67-2;Q9BZ67-3;Q9BZ67 Q9BZ67-2 FRMD8 FERM domain-containing protein 8 1 TT(0.012)S(0.987)FFSR;TT(0.012)S(0.987)FFSR 114.89 0.0084641 10055800.0 64063.0 68408.0 76748.0 71575.0 79945.0 82916.0 94415.0 89814.0 97479.0 82132.0 True False 63149.44987228462 68249.60547897503 70438.07569584722 76838.86426720054 75242.79227791744 79369.87596663642 99303.34672385694 93987.08632212674 86499.88852062322 96328.40676598926 0.6555641476111369 0.7085096470532717 0.7312284928262391 0.7976760630315968 0.7811069943335082 0.8239508845967917 1.0308833090647362 0.9756943925217169 0.8979686410754985 1.0 16.555673683922322 -6.689316546558101 0.8404705967159496 0.9840158383416958 0.6919137592439671 0.844116890204009 0.04875094787088777 0.23956996551232046 0.37179704643344896 0.03235909752128165 0.03299735778132919 2.0449535770646685e-07 6.689316546558101 -0.2921020790977287 TTS(ph)FKGTSPSSK ddPTM_PC-9_AZD4547_30min_R2 1 TTSFKGTSPSSK 12 1 F5GWA4;Q9H3F6-2;Q9H3F6;F8W8I7;F5H6V0;F5H497 F5GWA4 KCTD10 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 1 T(0.002)T(0.053)S(0.907)FKGT(0.004)S(0.007)PS(0.027)SK 101.61 0.012874000000000002 9154600.0 65299.0 54594.0 66520.0 63927.0 71034.0 69979.0 88220.0 92200.0 60453.0 62514.0 True False 86062.72369642425 72240.44285614221 65637.90133660416 49189.61781230446 61172.155236091996 65603.20206751117 96071.40909521445 77952.60854522634 63648.42216275447 60325.403887780725 1.4266414835202914 1.1975127922976898 1.0880640179169943 0.815404699217739 1.014036397499906 1.087488816312749 1.5925531020717176 1.2922020164214119 1.0550848906234482 1.0 15.88047804908617 TTS(ph)GDDACNLTSFR ddPTM_PC-9_AZD4547_30min_R2 1 TTSGDDACNLTSFR 14 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GUE9;Q96N67-7;A0A0U1RQT6 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 T(0.008)T(0.081)S(0.912)GDDACNLTSFR 222.55 9.095200000000001e-17 18392000.0 26416.0 40306.0 36348.0 29180.0 24685.0 32232.0 29232.0 43418.0 27567.0 23358.0 True False 34815.738513066666 53334.126273210844 35866.0017706387 22453.001826505915 21257.913844115934 30216.527944669484 31833.591370112365 36708.745746384346 29024.13534085408 22540.24352962186 1.544603476325029 2.3661734711570612 1.591198503401458 0.9961295137294637 0.9431093242705777 1.3405590718201261 1.4123002410456393 1.6285869182443646 1.2876584630823196 1.0 14.460215482330204 -5.517674097988543 8.348719144936673 1.2585411678752552 1.9623102885712447 0.5340087480782885 0.272213164941745 0.0918341461891231 61.4827740415865 0.07471183376648173 0.1399208732482273 3.036168722503938e-06 5.517674097988543 0.7037691206959895 TTS(ph)GDDACNLTSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTSGDDACNLTSFR 14 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GUE9;Q96N67-7;A0A0U1RQT6 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 TT(0.001)S(0.999)GDDACNLTSFR;TT(0.004)S(0.976)GDDACNLT(0.019)S(0.001)FR 136.33 1.7729000000000003e-05 22498000.0 55570.0 90470.0 57803.0 55363.0 57195.0 31069.0 51941.0 37210.0 37465.0 36389.0 True False 64976.90344247065 99451.26370459933 59181.2427390982 52261.190599267735 45988.050327742916 29439.686946151374 47020.77245972492 36233.27692725392 38012.854748183505 42986.0376448345 1.5115815972463498 2.3135713164888574 1.3767550111986149 1.215771293717922 1.0698369249036648 0.6848662626081576 1.0938615195991497 0.8429080443893383 0.8843070176008976 1.0 15.391580511652357 -5.685320027066561 1.7824664478368075 0.924503275575958 1.9148051421024463 0.7279272266264427 0.22911260342012355 0.16609873598636546 1.0647594521445114 0.0665914588604668 0.1512484666181694 2.0638587593705285e-06 5.685320027066561 0.9903018665264883 TTS(ph)PGGRPSAR ddPTM_PC-9_Lapatinib_30min_R1 1 TTSPGGRPSAR 11 1 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 T(0.007)T(0.026)S(0.961)PGGRPS(0.006)AR 98.156 0.02458 23021000.0 93302.0 69992.0 80443.0 67287.0 80152.0 87592.0 84198.0 77699.0 87457.0 66890.0 True False 91971.4963705088 69829.93782429559 73829.28705895993 72235.51044285177 75437.61694489508 83845.89434692486 88557.360456022 81309.17919414508 77606.67169696186 78451.84737467754 1.1723305371161354 0.8900993432416621 0.9410777378684181 0.920762389416565 0.9615785920835386 1.0687561498263507 1.1288116649832556 1.0364214727260816 0.989226822490499 1.0 16.25951979955233 -6.756925192495979 24.954753338488835 1.0521800960334633 0.9671936138705609 0.1421383635240624 0.07998467846651737 182.8365277404513 1010734.4150037848 0.026762162947073863 0.02590674395697015 1.7501481268036938e-07 6.756925192495979 -0.08498648216290239 TTS(ph)PLEEEER ddPTM_PC-9_AZD4547_30min_R2 2 TTSPLEEEER 10 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 T(0.006)T(0.119)S(0.875)PLEEEER;T(0.185)T(0.185)S(0.631)PLEEEER 186.74 0.00011546 52677000.0 265210.0 291220.0 272690.0 321010.0 289100.0 305830.0 308100.0 319720.0 289670.0 269750.0 True False 349541.26328931056 385351.1698825099 269073.9524275191 247006.10405506068 248963.45522924548 286706.4017534836 335520.30313121265 270314.6204347043 304981.36482697417 260306.13460550943 1.3428083968095328 1.4803768281008998 1.0336827168337663 0.9489061962730737 0.9564256163480218 1.10142007289987 1.288945047874839 1.0384489049570906 1.1716257294096026 1.0 17.989849786411867 -5.264776783450836 24.99731797564801 1.0697324463208302 1.4115926271025236 0.6467654803747842 0.10172578120093845 171.8078318480371 1286858.9055364695 0.02852786528864322 0.06356623728291258 5.435296204027586e-06 5.264776783450836 0.34186018078169345 TTS(ph)PLEEEER ddPTM_PC-9_Lapatinib_30min_R1 1 TTSPLEEEER 10 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 TT(0.003)S(0.997)PLEEEER 218.07 8.182499999999999e-08 35571000.0 90271.0 75926.0 88400.0 54522.0 88537.0 86824.0 81509.0 64633.0 87314.0 72002.0 True False 88983.7189863262 75750.19801187945 81132.0932338682 58531.72976006022 83329.42773043939 83110.73991662949 85729.13719340005 67636.08513436695 77479.77786281871 84447.44976336548 1.0537170658873896 0.8970098946047862 0.960740596207613 0.6931142376007206 0.9867607365757171 0.9841711046280065 1.0151773373100792 0.800925135381749 0.9174910323512285 1.0 16.36576623514805 TTS(ph)PPEVSGYSYEK ddPTM_PC-9_AZD4547_30min_R2 2 TTSPPEVSGYSYEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.133)T(0.002)S(0.865)PPEVSGYSYEK;T(0.061)T(0.114)S(0.824)PPEVS(0.001)GYSYEK 191.19 1.5668e-06 767897000.0 128045.0 129535.0 133680.0 232729.0 187957.0 172176.0 142795.0 171631.0 140968.0 157264.0 True False 168760.64649854717 171404.6555550133 131907.31585503957 179076.9246772067 161862.4149239822 161409.80750190566 155503.47836943073 145109.37263802346 148419.28068812427 151758.2352274363 1.1120361688815752 1.1294586768100816 0.8691937914100896 1.180014543585253 1.0665807669771794 1.0635983428510802 1.0246790109042947 0.9561877971271322 0.9779981986855079 1.0 17.211415281523472 -7.492863106028033 2.900018624613752 0.9755644635511007 1.0685696209981308 0.22351912345199276 0.07676742013288593 0.42052669779395513 7.097635609789067 0.0389883370002375 0.022398326870053192 3.2146736763074954e-08 7.492863106028033 0.09300515744703008 TTS(ph)PPEVSGYSYEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 TTSPPEVSGYSYEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.376)T(0.072)S(0.552)PPEVSGYSYEK;T(0.122)T(0.025)S(0.835)PPEVS(0.014)GY(0.001)S(0.002)YEK;T(0.394)T(0.08)S(0.526)PPEVSGYSYEK;T(0.016)T(0.02)S(0.964)PPEVSGYSYEK;T(0.017)T(0.001)S(0.981)PPEVSGYSYEK;T(0.005)T(0.026)S(0.969)PPEVSGYSYEK 136.83 6.1565e-05 753867000.0 294202.2 310374.0 294632.0 384532.0 404922.0 353129.0 371800.0 311518.0 338080.2 254697.2 True False 344004.82170168153 341185.8795296925 301657.14427808265 362987.9187095654 325580.440856898 334610.2935919242 336580.4124011031 303340.9825806037 343023.98334009905 300871.78617807385 1.1433601869803738 1.1339909396747436 1.002610274994492 1.2064538297875744 1.0821235350535665 1.112135829824475 1.1186838642354282 1.008206806074759 1.1401001991495374 1.0 18.198789300784384 -14.522878745156408 0.15342644456445786 0.6191614521106102 1.1340294445988326 0.23962994258262404 0.05812251928719322 193.74216427562664 1.7396583464503557 22.361996212299342 0.26577740561320234 3.0000000008560745e-15 14.522878745156408 0.5148679924882223 TTS(ph)PPEVSGYSYEK ddPTM_PC-9_Lapatinib_30min_R1 2 TTSPPEVSGYSYEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 T(0.161)T(0.033)S(0.806)PPEVSGYSYEK;T(0.019)T(0.101)S(0.88)PPEVSGYSYEK 153.0 0.00025864 811350000.0 268570.0 238692.0 280700.0 225483.0 290780.0 262390.0 207580.0 247679.0 276530.0 215398.0 True False 264740.1425502944 238139.32333919266 257621.92953333436 242065.77200923828 273676.8920954758 251168.19136096464 218327.47670325913 259187.07053664335 245384.27941000578 252629.2573002055 1.0479393613373025 0.9426434843063561 1.0197628425404266 0.9581858197904038 1.0833143200443285 0.9942165608415472 0.8642208706801338 1.0259582492800707 0.9713216989685786 1.0 17.946662203497603 -7.015130515156341 24.979839914697884 0.9620641552725778 1.0076830269282873 0.13120892118355443 0.054173145138480594 1423.3561752191697 2349899.141721082 0.01982388122002128 0.015917018836767584 9.65760602822169e-08 7.015130515156341 0.045618871655709436 TTS(ph)PSSDTDLLDR ddPTM_PC-9_AZD4547_30min_R2 1 TTSPSSDTDLLDR 13 0 Q96QT6;C9J9G2;Q96QT6-2;Q96QT6-5;Q96QT6-3;K7ENU0;K7ERZ4;K7EJ43 Q96QT6 PHF12 PHD finger protein 12 1 T(0.021)T(0.106)S(0.558)PS(0.153)S(0.153)DT(0.008)DLLDR 103.97 0.0013905999999999999 16606000.0 18379.0 19110.0 27807.0 30692.0 29647.0 25308.0 17324.0 28904.0 17691.0 24128.0 True False 24223.139693051646 25286.93378358208 27438.26101122895 23616.43358667304 25531.025794470548 23725.486759236017 18865.802438965056 24437.550947844054 18626.110143107682 23283.286063991618 1.0403660216378796 1.0860551948760004 1.1784531159312233 1.0143084409033072 1.0965387670924653 1.0189921944019869 0.8102723295635512 1.0495748272249914 0.799977721869491 1.0 14.507007065530429 -7.026196238657031 6.49396248251193 0.9179068566188354 1.0825723865338657 0.49007350138561145 0.08089587101774684 0.1526120582280423 23.460908294877598 0.0285428796479234 0.02288513900481385 9.414640940031747e-08 7.026196238657031 0.16466552991503025 TTS(ph)PSSDTDLLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTSPSSDTDLLDR 13 0 Q96QT6;C9J9G2;Q96QT6-2;Q96QT6-5;Q96QT6-3;K7ENU0;K7ERZ4;K7EJ43 Q96QT6 PHF12 PHD finger protein 12 1 T(0.005)TS(0.866)PS(0.043)S(0.074)DT(0.013)DLLDR 167.22 0.00028635 13286000.0 31326.0 25730.0 30953.0 32722.0 39272.0 33448.0 38333.0 34904.0 28044.0 32602.0 True False 36628.873083297374 28284.304356353958 31691.036909906205 30888.69242615537 31576.933516410852 31693.92799816121 34701.82073311328 33987.80698384494 28454.09044596444 38512.48452271 0.9510908874678833 0.7344191034903318 0.8228769787942055 0.8020436180361451 0.8199142150330654 0.8229520476528064 0.9010538053614886 0.8825140056545312 0.7388277022009749 1.0 15.233038577027928 -7.171043081766573 8.038098394705598 0.8707271337240403 0.819761461804451 0.10022656887968184 0.077477624205935 0.7846484863191658 62.842989447989595 0.028215525422060933 0.02183553571958983 6.744611182184465e-08 7.171043081766573 -0.05096567191958934 TTS(ph)PSSDTDLLDR ddPTM_PC-9_Lapatinib_30min_R1 2 TTSPSSDTDLLDR 13 0 Q96QT6;C9J9G2;Q96QT6-2;Q96QT6-5;Q96QT6-3;K7ENU0;K7ERZ4;K7EJ43 Q96QT6 PHF12 PHD finger protein 12 1 T(0.33)T(0.052)S(0.618)PSSDTDLLDR;TT(0.02)S(0.979)PS(0.001)SDTDLLDR 206.46 7.3201e-10 29093000.0 72788.0 60150.0 68172.0 57004.0 65553.0 70129.0 66595.0 63822.0 72837.0 52384.0 True False 71750.02977231548 60010.72637060498 62567.16131152999 61196.26431976951 61697.30142215675 67129.74614868361 70042.9632481625 66787.40311366583 64633.33005238707 61438.5046027075 1.1678348982659577 0.9767608563825689 1.0183705107427492 0.9960571910969441 1.0042122903401176 1.0926331391491144 1.1400499361287484 1.0870610140260903 1.052000377781636 1.0 15.906855481212146 -6.769990126005456 24.947771177715822 1.0838965309062383 1.0267164323115234 0.09543313639973061 0.05934779199576904 323.9661987384656 945202.0526434451 0.020389678580695656 0.01825893613459929 1.6982822636803545e-07 6.769990126005456 -0.057180098594714845 TTS(ph)RSPVLSR ddPTM_PC-9_AZD4547_30min_R2 1 TTSRSPVLSR 10 1 C9J840;A0A0D9SG62;O95819-2;G5E948;O95819-3;A0A0D9SEY1;H7C3Z6;O95819-6;E7EN19 C9J840;O95819-6;E7EN19 MAP4K4 1 T(0.049)T(0.192)S(0.757)RS(0.002)PVLSR 77.124 0.010473 23007000.0 13945.0 16883.0 23515.0 34881.0 37187.0 29067.0 21925.0 25761.0 25093.0 26542.0 True False 18379.21992598101 22340.09958494066 23203.17573557194 26839.724356077902 32024.226944344333 27249.43589500211 23876.28252564701 21780.22937888912 26419.364751625195 25612.772658756057 0.7175802546194794 0.8722249591085723 0.9059220586819066 1.0479038998888859 1.2503225391100496 1.0639002757745768 0.9322021806758432 0.8503659353507464 1.031491791365797 1.0 14.644575816964261 -5.104972619725651 1.571429757316406 1.0221678482422665 0.7072272782472996 0.4783811308653171 0.09986458999514829 0.6082498236994075 2.1828447149920436 0.03321773121677961 0.2444708819599368 7.852851416744056e-06 5.104972619725651 -0.3149405699949669 TTS(ph)SANNPNLMYQDECDR ddPTM_PC-9_AZD4547_30min_R2 2 TTSSANNPNLMYQDECDR 18 0 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 1 T(0.339)T(0.082)S(0.467)S(0.111)ANNPNLMYQDECDR;T(0.089)T(0.089)S(0.775)S(0.023)ANNPNLMY(0.024)QDECDR 125.45 3.3165e-05 0.0 12540.4 13608.8 15531.0 24348.0 21718.6 22881.5 20909.9 22761.0 17118.8 22029.5 True False 16527.98634347598 18007.578465411396 15325.048792224865 18734.944772850115 18703.347280324757 21450.71618782434 22770.84059215628 19243.810445747262 18023.664819277135 21258.253910257936 0.7774856022159271 0.8470864324713911 0.7208987556983658 0.8813021451310153 0.8798157816385692 1.009053531789529 1.0711529125714536 0.9052394673139816 0.847843143438042 1.0 14.375735482605501 -6.24728595680169 1.9576610650582016 0.9640909996575745 0.7912610004569505 0.5601603334941805 0.06770407734119115 0.2684592566260208 2.021834739394236 0.024527512091746567 0.03236605863526058 5.658665772326846e-07 6.24728595680169 -0.17282999920062403 TTS(ph)SSDLTTSSSSSGPR ddPTM_PC-9_AZD4547_30min_R2 1 TTSSSDLTTSSSSSGPR 17 0 Q5QP82;A0A0A0MQT4 Q5QP82 DCAF10 DDB1- and CUL4-associated factor 10 1 T(0.011)T(0.054)S(0.933)S(0.002)SDLTTSSSSSGPR 119.0 0.00010496 4009500.0 22188.0 27413.0 38178.0 50153.0 43368.0 38734.0 32726.0 39564.0 32719.0 33171.0 True False 29243.32246092986 36273.716159567535 37671.73477493795 38591.0007061258 37347.101786170555 36311.956856813944 35638.5506013375 33450.2928902748 34448.45954283762 32009.693386466628 0.9135770876610033 1.1332103598000627 1.17688521161734 1.2056035726490801 1.1667435028278192 1.1344050197046331 1.113367446887358 1.0450051016239115 1.0761883635349683 1.0 14.96622123725323 -7.708116563695353 3.1128091876137858 1.0428433466620721 1.1304821789018928 0.1804564593932082 0.07692580765238315 0.447661112828187 8.74852042990952 0.045700290193290916 0.022406760588052212 1.958318994400315e-08 7.708116563695353 0.08763883223982072 TTS(ph)SSDLTTSSSSSGPR ddPTM_PC-9_Lapatinib_30min_R1 2 TTSSSDLTTSSSSSGPR 17 0 Q5QP82;A0A0A0MQT4 Q5QP82 DCAF10 DDB1- and CUL4-associated factor 10 1 TT(0.001)S(0.975)S(0.024)S(0.001)DLTTSSSSSGPR;T(0.001)T(0.13)S(0.8)S(0.058)S(0.01)DLTTS(0.001)SSSSGPR 150.12 5.6161000000000007e-05 3622200.0 13589.7 15039.9 21382.4 19717.1 22710.0 27409.0 27276.0 30343.0 29215.0 23008.0 True False 13395.908385954248 15005.076035598702 19624.42161045091 21167.16130831745 21374.242449577876 26236.78096349968 28688.217817507015 31752.846552567506 25924.49905241139 26984.90214376707 0.4964223444126298 0.556054491346916 0.7272370863491802 0.7844075622563117 0.7920815252804192 0.972276305606682 1.0631210617205582 1.176689334776844 0.9607038378087797 1.0 14.71986483517729 -5.952562754287037 0.6343718403253733 1.0790625562064433 0.44674059294447965 0.8882693426946379 0.06978926160003632 0.34381454785319715 0.2559963028092888 0.04505468928084607 0.13138566737153215 1.1154169652046863e-06 5.952562754287037 -0.6323219632619637 down TTSAT(ph)PLKDNTQQFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTSATPLKDNTQQFR 15 1 Q14207 Q14207 NPAT Protein NPAT 1 T(0.072)T(0.01)S(0.029)AT(0.888)PLKDNT(0.001)QQFR 58.635 0.041765 11151000.0 19102.0 12776.0 23019.0 23207.0 28401.0 24816.0 19720.0 25247.0 18094.0 17750.0 True False 22335.591318302584 14044.316846357491 23567.86026004365 21906.78702810914 22836.027928284395 23514.605273928737 17851.978839563653 24584.293001407685 18358.590519515066 20967.9344910773 1.0652261112226995 0.6697997293121034 1.123995321049516 1.0447756328803564 1.0890928688279737 1.1214554911899 0.8513942490215424 1.1724708989275645 0.8755555072593052 1.0 14.355897131005566 -5.288920563197226 24.99940001638505 1.039836036202803 0.8675127498755328 0.20212383803339884 0.13268516446382073 898.7351625991478 817570.3289496058 0.032047288054565595 0.0667362368369433 5.1413768390512285e-06 5.288920563197226 -0.17232328632727012 TTSAT(ph)PLKDNTQQFR ddPTM_PC-9_Lapatinib_30min_R1 2 TTSATPLKDNTQQFR 15 1 Q14207 Q14207 NPAT Protein NPAT 1 T(0.002)T(0.003)S(0.032)AT(0.963)PLKDNTQQFR;T(0.006)T(0.018)S(0.018)AT(0.958)PLKDNTQQFR 73.415 0.012722 26357000.0 55591.0 51859.0 53201.0 53500.0 44339.0 47883.0 39691.0 41044.0 53237.0 38044.0 True False 54798.26214585916 51738.923671707475 48827.019141798795 57434.56847076815 41731.067193828 45835.15571072478 41746.005770445445 42951.054078488625 47240.88844953701 44619.85470955647 1.2281138632690958 1.1595493532753767 1.0942890661484215 1.2871975680921948 0.9352578009378913 1.0272367762978847 0.93559259755959 0.9625995951369507 1.0587414225582221 1.0 15.445398195459077 -6.271371350103387 24.999843515862366 0.9841856725713181 1.1829491426360674 0.7473886872718749 0.05847990679366008 343.65389990869494 865012.5293762905 0.017616572005926135 0.020221230868089208 5.353387122450488e-07 6.271371350103387 0.19876347006474937 TTSESSS(ph)SPSASLK ddPTM_PC-9_AZD4547_30min_R2 2 TTSESSSSPSASLK 14 0 Q96CB8;A0A087WXN4 Q96CB8 INTS12 Integrator complex subunit 12 1 TTSES(0.099)S(0.077)S(0.408)S(0.408)PS(0.007)AS(0.001)LK;TTSES(0.001)S(0.098)S(0.427)S(0.427)PS(0.042)AS(0.004)LK 95.195 0.0032579 9698600.0 64854.0 77088.0 74917.0 77477.0 77285.0 76504.0 67894.0 93928.0 79587.0 76556.0 True False 85476.22295299907 102005.18846199758 73923.55163010175 59615.87465771762 66555.31178620618 71720.19278601973 73936.43447189417 79413.58585071609 83793.80633991916 73875.7977418329 1.1570260567839163 1.3807659826356926 1.0006464077509625 0.8069743607514311 0.900908197550584 0.9708212293917128 1.0008207928971973 1.0749607892998407 1.134252473763408 1.0 16.172814183749566 -3.099704381154041 7.2967385091175565 1.0393770584526034 1.1714724280217363 0.0 0.14935761560081687 0.0 0.0 0.03827953512387617 0.0 0.0007948691081246252 3.099704381154041 0.13209536956913293 TTSESSSSPS(ph)ASLK ddPTM_PC-9_Lapatinib_30min_R1 1 TTSESSSSPSASLK 14 0 Q96CB8;A0A087WXN4 Q96CB8 INTS12 Integrator complex subunit 12 1 TTSES(0.004)S(0.053)S(0.251)S(0.251)PS(0.438)AS(0.003)LK 108.97 0.0006346 6354500.0 40088.0 78900.0 78828.0 65583.0 79098.0 81397.0 85780.0 84135.0 85373.0 70988.0 True False 39516.337768761136 78717.31189760147 72347.06612487954 70406.1925984745 74445.6111526513 77915.84005567452 90221.26867523656 88044.21924991815 75757.39372245476 83258.18121443583 0.47462408128979816 0.9454603829845969 0.8689484332902476 0.845636928065239 0.8941537043778642 0.9358340396002427 1.083632471418838 1.057484297226667 0.9099093040158732 1.0 16.345304422515042 -4.761396704461431 9.909402279076971 0.9472800148416176 0.472577400868986 0.7884577085673277 0.07371130143818719 0.03734187346151756 75.0438127013526 0.02088038941057524 0.11835183473373925 1.7322209849186697e-05 4.761396704461431 -0.47470261397263164 TTSFFLNS(ph)PEKEHQEMDEGSQSLEK ddPTM_PC-9_AZD4547_30min_R2 2 TTSFFLNSPEKEHQEMDEGSQSLEK 25 1 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 TTSFFLNS(0.995)PEKEHQEMDEGS(0.004)QSLEK;TTSFFLNS(0.999)PEKEHQEMDEGSQSLEK 88.41799999999999 1.161e-05 15022100.0 68865.0 86008.0 86030.0 85612.0 83697.0 75420.0 97988.0 89882.0 83084.0 102644.0 True False 90762.63751901635 113808.40402189041 84889.18598899663 65875.47609221477 72077.11626538282 70703.97547738181 106708.74217209099 75992.80218288559 87475.65062065225 99050.46480240228 0.9163272247139933 1.1489941440348517 0.8570296581479324 0.6650698330758069 0.7276807474772671 0.7138177051307186 1.07731692511455 0.7672129791060055 0.8831422527411572 1.0 16.595876124644498 -5.4098644725706935 6.7238141333203085 0.8199437225227819 1.0304326571831635 0.25597782665020263 0.13281690991387282 0.29729721173051776 15.59531303635561 0.03503649584816987 0.07356147444826903 3.8916657070520245e-06 5.4098644725706935 0.21048893466038154 TTSFFLNS(ph)PEKEHQEMDEGSQSLEK ddPTM_PC-9_Lapatinib_30min_R1 1 TTSFFLNSPEKEHQEMDEGSQSLEK 25 1 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 T(0.003)T(0.003)S(0.009)FFLNS(0.965)PEKEHQEMDEGS(0.018)QS(0.002)LEK 52.97 0.018934 7481200.0 22743.0 31907.0 26330.0 21835.0 22766.0 31200.0 26327.0 30094.0 20724.0 25366.0 True False 22418.68064944461 31833.121301860225 24165.24903673922 23440.818739424725 21426.948639678118 29865.648730752284 27690.083240999676 31492.277103548327 18389.844886605282 29750.47930192959 0.7535569569123061 1.070003645278937 0.8122641921662043 0.787913986243051 0.7202219642319639 1.0038711789364423 0.9307441053295474 1.0585468820163098 0.6181360878247273 1.0 14.860625291027063 -6.779293105335243 24.999670745232894 0.9264490750232816 0.8390035064287347 0.09509798666518798 0.14213567731112386 681.6324906171457 954449.5258733095 0.04949494179123871 0.043739208242082425 1.6622903919616945e-07 6.779293105335243 -0.08744556859454689 TTSIS(ph)PALAR ddPTM_PC-9_AZD4547_30min_R2 3 TTSISPALAR 10 0 Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5;Q9UKE5-8;Q9UKE5-5;Q9UKE5-7;Q9UKE5-3 Q9UKE5-6 TNIK TRAF2 and NCK-interacting protein kinase 1 T(0.004)T(0.013)S(0.195)IS(0.788)PALAR;T(0.023)T(0.002)S(0.002)IS(0.973)PALAR;T(0.328)T(0.031)S(0.002)IS(0.64)PALAR 152.69 0.00017112 379327400.0 993419.0 1024855.0 1157251.0 1867627.0 1469609.0 1413817.0 1196050.0 1602488.0 1206832.0 1407019.0 True False 1309305.5776011548 1356119.3366181573 1141905.0956056283 1437074.4496995134 1265579.1576478567 1325410.799489599 1302496.1329441315 1354860.301110873 1270622.6757236423 1357759.6930732501 0.9643131875844533 0.9987918654063298 0.841021501397614 1.0584159015994477 0.9321083576897577 0.976174801955985 0.9592979815124493 0.9978645764952601 0.9358229458466427 1.0 20.372796732051427 -14.522878743106078 0.1834911175867571 1.1480720259246915 0.9564108119362301 0.038744138302745035 0.05335603553804393 524.1372301403178 5.061429471766955 28.443506858860964 0.1497873754885947 3.0000000150192504e-15 14.522878743106078 -0.19166121398846137 TTSIS(ph)PALAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTSISPALAR 10 0 Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5;Q9UKE5-8;Q9UKE5-5;Q9UKE5-7;Q9UKE5-3 Q9UKE5-6 TNIK TRAF2 and NCK-interacting protein kinase 1 T(0.077)T(0.01)S(0.283)IS(0.63)PALAR;T(0.053)T(0.001)S(0.154)IS(0.792)PALAR 94.82 0.0061551999999999996 249380000.0 107333.0 149727.0 141960.0 129266.0 164070.0 129744.0 142545.0 130001.0 101825.0 92307.0 True False 125502.3569766184 164590.90704872922 145344.86478629822 122023.64510602651 131921.66128634952 122939.99623874167 129042.10566357 126588.61149744531 103313.9979910258 109041.52839818988 1.150959261303804 1.5094332358190008 1.332931287018818 1.1190566282272703 1.2098295321449242 1.1274603175938471 1.1834216519081011 1.1609211037026028 0.9474738616442654 1.0 16.73451816360229 -6.744862128764982 0.37513394106023285 0.9853678926215983 1.3876332067882857 0.49596205509705316 0.10687699465099729 1.4091224434768241 0.4068321872165071 0.1189004018963049 0.21795435789423961 1.7994420757957377e-07 6.744862128764982 0.4022653141666874 TTSIS(ph)PALAR ddPTM_PC-9_Lapatinib_30min_R1 4 TTSISPALAR 10 0 Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5;Q9UKE5-8;Q9UKE5-5;Q9UKE5-7;Q9UKE5-3 Q9UKE5-6 TNIK TRAF2 and NCK-interacting protein kinase 1 T(0.012)T(0.041)S(0.215)IS(0.732)PALAR;T(0.02)T(0.065)S(0.213)IS(0.702)PALAR;T(0.114)T(0.002)S(0.051)IS(0.832)PALAR;T(0.302)T(0.006)S(0.042)IS(0.65)PALAR 98.75399999999999 0.0046373000000000004 356800900.0 253909.0 279901.0 286926.0 221223.0 275138.0 241313.0 222322.0 226669.0 279843.0 204748.0 True False 250288.2110987915 279252.906431566 263336.05184639 237492.47739829382 258954.92378212072 230992.6055180777 233832.74533009954 237200.86923586729 248324.13446256923 240138.41899043895 1.042266423469527 1.1628830888683597 1.096601089294565 0.9889815981829609 1.0783569112797022 0.9619144095692352 0.9737415042255673 0.987767264534674 1.0340874879852364 1.0 17.87350670871301 -5.720709071712737 6.326029283174826 1.0031497321738907 1.1081231516450256 0.5353549103546873 0.04129194633962 0.13653113332276837 14.00055988441906 0.01121166729785205 0.019241288915771072 1.9023522144587154e-06 5.720709071712737 0.10497341947113492 TTSPPEVSGYSYEK ddPTM_PC-9_Lapatinib_30min_R1 1 TTSPPEVSGYSYEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 0 153.74 1.4604999999999999e-08 0.0 4417.5 5294.6 8425.0 5842.7 8505.3 6815.1 6998.6 7344.7 7499.1 6031.5 False True 4354.505639929716 5282.340678999253 7732.329021440484 6272.391648675833 8005.034976063171 6523.634059774042 7360.953263587201 7685.9615751455885 6654.472388976152 7074.03673853143 0.6155616377013207 0.7467222569296221 1.0930575154244555 0.8866778447036989 1.1316077752976181 0.9221939750808176 1.0405590945680239 1.0865029203596126 0.9406895433169068 1.0 12.78831799625951 -5.100088778983718 3.7938038234998777 1.012846297214035 0.6362930031985303 0.7578207600936163 0.07634773765874002 0.09644905569856362 2.442285044788386 0.018401987073457575 0.060731927234801183 7.94165873817128e-06 5.100088778983718 -0.37655329401550475 TTSQAHS(ph)LPLSPASTR ddPTM_PC-9_AZD4547_30min_R2 1 TTSQAHSLPLSPASTR 16 0 P19838;P19838-2;P19838-3 P19838 NFKB1 Nuclear factor NF-kappa-B p105 subunit;Nuclear factor NF-kappa-B p50 subunit 1 T(0.048)T(0.048)S(0.048)QAHS(0.638)LPLS(0.179)PAS(0.027)T(0.014)R 60.541000000000004 0.025542 15025000.0 10600.0 8796.9 28627.0 57159.0 47500.0 37524.0 23254.0 48721.0 27446.0 38610.0 True False 13970.579506303253 11640.325892244542 28247.387275450474 43981.875647746834 40905.44490968232 35177.61834809437 25323.560951032876 41192.288947201465 28896.739527880465 37258.27565196938 0.37496580992643985 0.31242256085539655 0.7581506868248581 1.1804592369916094 1.0978888366112607 0.9441558347114481 0.6796761392712047 1.1055876372803675 0.7755790900739942 1.0 15.185273286090986 -5.398641055115712 3.63836368476706 0.9663444523844767 0.3436611260837163 0.7428105738664503 0.14501182892315528 0.11587408522243581 2.724496901651884 0.04024433431101319 0.0918981902805398 3.9935483322407585e-06 5.398641055115712 -0.6226833263007605 down TTSQAHSLPLS(ph)PASTR ddPTM_PC-9_AZD4547_30min_R2 4 TTSQAHSLPLSPASTR 16 0 P19838;P19838-2;P19838-3 P19838 NFKB1 Nuclear factor NF-kappa-B p105 subunit;Nuclear factor NF-kappa-B p50 subunit 1 TTSQAHS(0.001)LPLS(0.993)PAS(0.004)T(0.001)R;TTSQAHSLPLS(0.632)PAS(0.184)T(0.184)R;TTSQAHS(0.001)LPLS(0.997)PAS(0.002)TR;T(0.005)T(0.005)S(0.014)QAHS(0.081)LPLS(0.74)PAS(0.078)T(0.078)R 149.19 3.0557e-05 53916000.0 47924.0 44055.1 192884.0 351263.0 237230.0 219459.0 117630.6 258479.0 152580.0 216701.0 True False 63162.835118875155 58295.049530564436 190326.2321318333 270284.7423092511 204294.70938787208 205736.19403726744 128099.49551933313 218537.00980652406 160645.0673017565 209114.36394865118 0.3020492419850462 0.2787711395324283 0.9101537959322996 1.2925211697825814 0.976952063599215 0.9838453473611537 0.6125810446516645 1.0450597734175098 0.7682163208128711 1.0 17.67393263768306 -5.27394910493185 6.201777710135865 0.9543261034974505 0.28652766808144203 0.713339210368259 0.1669879675781369 0.07575377965799986 13.537203990417458 0.04530356066126213 0.10405823591313736 5.3217062080755425e-06 5.27394910493185 -0.6677984354160085 TTSQAHSLPLS(ph)PASTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TTSQAHSLPLSPASTR 16 0 P19838;P19838-2;P19838-3 P19838 NFKB1 Nuclear factor NF-kappa-B p105 subunit;Nuclear factor NF-kappa-B p50 subunit 1 TTSQAHS(0.066)LPLS(0.519)PAS(0.306)T(0.108)R;TTSQAHSLPLS(0.996)PAS(0.003)T(0.001)R;TTSQAHSLPLS(0.333)PAS(0.333)T(0.333)R;TTSQAHS(0.045)LPLS(0.937)PAS(0.014)T(0.004)R;TTSQAHSLPLS(0.91)PAS(0.066)T(0.024)R 130.01 8.6768e-06 44798000.0 67069.9 91760.5 196454.0 190066.6 266964.0 254002.0 230912.0 204412.0 231414.0 152129.0 True False 78423.50937909243 100869.87601598198 201138.20841594346 179417.7846062313 214654.32061710933 240681.68797503415 209038.34370189306 199046.401592417 234797.99195772377 179708.7834474987 0.4363921889327329 0.5612963043926608 1.1192452842724034 0.9983807199866087 1.1944564784159248 1.3392872811102663 1.1632060475383659 1.1076053032798352 1.3065471116848288 1.0 17.45530139817876 -5.208962241246764 1.9916145156707161 1.1760908993146284 0.39423939602428554 0.8557792673777715 0.10770350331457924 0.1316216310388941 0.9160479102483954 0.03011472671745009 0.13465980287707158 6.180701345149222e-06 5.208962241246764 -0.7818515032903428 down TTSQAHSLPLS(ph)PASTR ddPTM_PC-9_Lapatinib_30min_R1 3 TTSQAHSLPLSPASTR 16 0 P19838;P19838-2;P19838-3 P19838 NFKB1 Nuclear factor NF-kappa-B p105 subunit;Nuclear factor NF-kappa-B p50 subunit 1 TTSQAHS(0.001)LPLS(0.896)PAS(0.075)T(0.028)R;TTSQAHS(0.01)LPLS(0.85)PAS(0.102)T(0.038)R;TTSQAHS(0.007)LPLS(0.91)PAS(0.076)T(0.007)R 84.113 0.0028626 31437000.0 126974.0 84383.0 236535.0 116068.0 199528.0 243210.0 131528.0 171032.0 290428.0 124982.0 True False 125163.32747582004 84187.61634797619 217088.0053515039 124604.02791149761 187792.15532714102 232808.475250201 138337.8762685533 178978.77110301287 257716.94029757736 146584.972171953 0.8538619315559572 0.574326379440991 1.4809704032746727 0.8500464001543732 1.2811146500532777 1.588215161490788 0.9437384625367642 1.2209899040200383 1.758140254618051 1.0 17.16137768101698 -5.25616178328028 24.996750755730073 1.2590625125795551 0.7140941234020829 0.3834217544284536 0.27955428596577836 436.46693921303466 2067261.1476785447 0.07012879178692473 0.17442828381438444 5.544191423933764e-06 5.25616178328028 -0.5449683891774723 TTSSANNPNLMY(ph)QDECDR ddPTM_PC-9_AZD4547_30min_R2 1 TTSSANNPNLMYQDECDR 18 0 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 1 T(0.1)T(0.025)S(0.1)S(0.186)ANNPNLMY(0.59)QDECDR 104.94 0.00037127 4360500.0 6390.1 7838.3 7487.0 16088.0 11839.0 11780.0 10522.0 12225.0 10345.0 9873.3 True False 8422.018877663055 10371.877188689245 7387.717488081108 12379.16015712225 10195.359206015346 11043.39473778253 11458.437616185085 10335.907152553063 10891.815580263923 9527.638772198634 0.8839565687815805 1.088609406451688 0.7753985709070171 1.2992894098004923 1.0700824674173313 1.1590904107329119 1.2026523979498955 1.084834070610751 1.1431809959090722 1.0 13.217903001029864 -5.761436206437392 24.999999999999748 1.1414186819992536 0.9332503279487123 0.4828908115540559 0.10428887081416707 0.07872657017194189 559472.31641411 0.026964257135824978 0.04309746669942659 1.7320634350469942e-06 5.761436206437392 -0.20816835405054124 TTSVSLTIGSS(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTSVSLTIGSSSPK 14 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;D6R9Z5;D6RBH5;D6RBB1;H0Y952;Q8WX93-6 Q8WX93-3 PALLD Palladin 1 TTSVSLTIGS(0.016)S(0.492)S(0.492)PK 157.33 0.00038536 5499100.0 29638.0 29380.0 22057.0 33797.0 33940.0 24085.0 31568.0 29562.0 27180.0 22396.0 True False 34655.12802281708 32296.65223434432 22582.922531638313 31903.463661352376 27289.700640328603 22821.940200780693 28577.65050747188 28786.02882352808 27577.45608049187 26456.217513361535 1.3099048647190303 1.2207584934631384 0.8535960410906419 1.2058966345147317 1.0315042438151305 0.8626305022346685 1.0801865570177949 1.0880629027558413 1.0423809097639924 1.0 14.69131919155179 -5.061394841622804 7.244005612309685 1.0272508641183693 1.2889174383880209 0.5047591433431916 0.09856172539515051 0.17930287623981733 18.5780270001411 0.024801520414832398 0.06783740756422184 8.68170767337975e-06 5.061394841622804 0.26166657426965156 TTSVSLTIGSSS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 TTSVSLTIGSSSPK 14 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;D6R9Z5;D6RBH5;D6RBB1;H0Y952;Q8WX93-6 Q8WX93-3 PALLD Palladin 1 TTSVSLTIGSS(0.037)S(0.963)PK;TTSVSLTIGS(0.002)S(0.068)S(0.93)PK 204.18 1.1242e-10 12481000.0 96871.0 94523.0 72635.0 109950.0 99498.0 103939.0 90723.0 99163.0 87136.0 87328.0 True False 127673.96295802882 125075.71125198984 71671.81244113404 84602.72621056632 85684.42016049613 97439.67789901336 98797.17124626109 83839.63688904869 91741.83106833023 84270.67330057452 1.515046195283673 1.4842139780451609 0.8504953103376405 1.0039403139548613 1.0167762615931535 1.156270314246428 1.1723790421594689 0.9948850959100751 1.0886566758652534 1.0 16.362743031535906 -5.243911289975036 24.28382360059528 1.0426592973522628 1.4996302875893832 0.8201307574762423 0.08690456765559759 233.63792772784922 323685.4495591054 0.023531110940390856 0.061908371686681146 5.702807472879375e-06 5.243911289975036 0.4569709902371204 TTSVSLTIGSSS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTSVSLTIGSSSPK 14 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;D6R9Z5;D6RBH5;D6RBB1;H0Y952;Q8WX93-6 Q8WX93-3 PALLD Palladin 1 TTSVSLTIGS(0.002)S(0.022)S(0.976)PK 236.42 6.535400000000001e-27 4452300.0 37200.0 34585.0 23951.0 37846.0 34793.0 30292.0 38109.0 32381.0 30124.0 29050.0 True False 43497.22526650904 38018.37023569767 24522.082674673315 35725.6113183875 27975.56141364032 28703.434193981688 34499.039634732835 31531.03306050548 30564.506510991036 34316.53504032655 1.267529638857593 1.1078732217871348 0.7145850432118676 1.041061146657292 0.8152210408412525 0.836431596612283 1.0053182698717054 0.9188291598627971 0.8906641208115454 1.0 15.066616270018052 -5.030362417760961 5.71162951287548 0.9026200244478154 1.2346833348014763 0.6153803621545756 0.09397803443939863 0.09370215953105598 9.558292966065064 0.022702216624653215 0.06980975378877015 9.324758270603541e-06 5.030362417760961 0.3320633103536609 TTSVSLTIGSSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 TTSVSLTIGSSSPK 14 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-2;Q8WX93-9;Q8WX93-5;D6R9Z5;D6RBH5;D6RBB1;H0Y952;Q8WX93-6 Q8WX93-3 PALLD Palladin 1 TTSVSLTIGS(0.001)S(0.027)S(0.972)PK;TTSVSLTIGS(0.014)S(0.286)S(0.7)PK 193.45 1.6363e-07 10003300.0 101632.0 90420.0 75858.0 82608.0 73472.0 67462.0 69306.0 66606.0 63623.0 54215.0 True False 100182.7090429739 90210.63804538807 69621.24806034789 88683.2678922095 69150.5214115097 64576.807521602925 72894.32556313748 69700.75791715765 56457.10776010848 63585.990513053366 1.5755468812333389 1.4187187667835262 1.0949148939663929 1.394698221678311 1.0875119008693277 1.0155823161761734 1.146389715328461 1.096165324386179 0.8878859526221988 1.0 15.956421320472527 -1.5228787455568025 0.31717599971824695 0.9878741518751516 6.623003900686759 0.741972783064087 0.10503586927930372 28.78243837119227 0.4109179285086084 0.09997346217238859 93.79578081964925 0.02999999998090248 1.5228787455568025 5.635129748811607 TTT(ph)PPDSGVLFEGLGISTRPR ddPTM_PC-9_AZD4547_30min_R2 2 TTTPPDSGVLFEGLGISTRPR 21 1 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 T(0.163)T(0.163)T(0.666)PPDS(0.008)GVLFEGLGISTRPR;T(0.096)T(0.096)T(0.696)PPDS(0.111)GVLFEGLGISTRPR 112.82 8.9859e-06 25815000.0 49995.0 63371.0 82254.0 89868.0 84862.0 78532.0 62846.0 69717.0 73168.0 61763.0 True False 65892.37003939919 83854.4364625526 81163.25821619114 69150.32104675923 73080.37612474643 73621.38162542746 68439.17225116584 58943.83958728353 77035.51110456741 59600.69616919406 1.1055637647644982 1.4069371979231113 1.3617837279246776 1.1602267337692795 1.2261664849901475 1.235243652463917 1.1482948463702702 0.9889790451432673 1.292527035017838 1.0 15.8630415618137 -7.521752980954035 0.3706319792473257 1.0193752437638361 1.3103309037990154 0.28870925443900575 0.11208927161970439 1.5034491374555001 0.5566221099209955 0.13760253348063167 0.14873932950993912 3.007786592186002e-08 7.521752980954035 0.29095566003517925 TTT(ph)SPFFSEDTFR ddPTM_PC-9_AZD4547_30min_R2 1 TTTSPFFSEDTFR 13 0 A0A494C0H4;H0Y9M2;Q17R98-2;Q17R98;A0A5F9ZGT0;H0Y9K9;G5E9Z1;A0A590UJE4;Q17R98-3;A0A5F9ZHK5 A0A494C0H4 ZNF827 Zinc finger protein 827 1 T(0.001)T(0.001)T(0.986)S(0.011)PFFS(0.001)EDTFR 113.07 0.00094295 8820500.0 35752.0 38889.0 58052.0 71308.0 58731.0 60843.0 52262.0 63719.0 44054.0 48433.0 True False 47120.392312203214 51459.10873415613 57282.19254949702 54869.04229761766 50577.21442085369 57038.477591757364 56913.216755090754 53872.69266695533 46382.604501976464 46737.37541185786 1.0081950879134771 1.1010269250399607 1.2256185129078474 1.1739863827205133 1.0821577800455953 1.2204039505668516 1.2177238506347783 1.152668334330283 0.992409267598895 1.0 15.512289099835955 -8.260678793304297 24.401470699470725 0.9962046099690589 1.1522086665298148 0.459017342280043 0.06565191558946681 43.20862011102537 1386416.7701623952 0.05346044196204491 0.017481642341771866 5.486826237116103e-09 8.260678793304297 0.1560040565607559 TTTAAAVAST(ph)GPSSRSPSTLLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTTAAAVASTGPSSRSPSTLLPK 23 1 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 TTT(0.001)AAAVAS(0.273)T(0.49)GPS(0.014)S(0.046)RS(0.162)PS(0.007)T(0.007)LLPK 65.118 0.0013176 58357000.0 38156.0 7991.2 23431.0 51742.0 57494.0 61628.0 38433.0 85445.0 63440.0 37651.0 True False 44615.057184648365 8784.513523999056 23989.68390256235 48843.063489827364 46228.46342413236 58396.11919010644 34792.348009175985 83202.15928646112 64367.6899833114 44476.828254848006 1.003107886403417 0.19750764316341596 0.5393748799960225 1.098168763517966 1.0393830953782865 1.3129560151075121 0.7822578491842793 1.8706855356168979 1.447218529488898 1.0 15.440766289369964 -5.901035718868168 2.340853359138567 1.2674778944129008 0.5323936074384326 0.4393114434243429 0.33170442763595726 0.2639029991647838 2.9365569857783216 0.10312562450957495 0.1712296376541037 1.2559266648373643e-06 5.901035718868168 -0.7350842869744683 TTTAAAVASTGPSS(ph)RSPSTLLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTTAAAVASTGPSSRSPSTLLPK 23 1 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 TTTAAAVAS(0.029)T(0.081)GPS(0.073)S(0.337)RS(0.299)PS(0.09)T(0.09)LLPK 52.541000000000004 0.009117299999999998 57137000.0 48867.0 6853.5 36877.0 59056.0 70337.0 70850.0 60940.0 103520.0 74900.0 49716.0 True False 57139.2179327553 7533.870186796418 37756.2875368013 55747.28378213531 56554.969768379306 67134.50127570324 55167.32203260699 100802.7096885067 75995.27080312131 58729.11724836057 0.9729282613106253 0.12828168615128857 0.6428887288929116 0.9492273406117219 0.9629800756107575 1.1431212390235153 0.9393521411076036 1.7164008997823073 1.2939964767688166 1.0 15.841788332539162 -6.298782310334558 0.893615505811697 1.3010391413979412 0.5118363320239798 0.4800466839310945 0.28016797103012064 0.4780185472646927 0.8207549456985334 0.1416457062509835 0.22090465825114605 5.025944513497334e-07 6.298782310334558 -0.7892028093739614 TTTAAAVASTGPSSR ddPTM_PC-9_Lapatinib_30min_R1 1 TTTAAAVASTGPSSR 15 0 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 0 101.72 0.0074603000000000004 1751300.0 6536.4 5393.0 6189.4 8021.1 5934.0 3618.2 7100.5 6411.3 7118.5 4762.4 False True 6443.189737371043 5380.512839844933 5680.531423774921 8610.998451605206 5584.973786692868 3463.458020436152 7468.129146986669 6709.192403601357 6316.739568871826 5585.574494500883 1.1535410983623082 0.9632872760254407 1.0170003872238254 1.5416495581757825 0.9998924537111435 0.6200719413635966 1.3370386796092688 1.2011642509121845 1.1309023942104417 1.0 12.447489958878743 -10.545239751820874 3.891380669212513 0.9999838156900697 1.1051102547669693 0.01903332002936975 0.23039196300567022 122800043.51863648 203397107.6585712 25636.166882483692 0.06135036173168413 2.8494448001648786e-11 10.545239751820874 0.10512643907689967 TTTAAAVASTGPSSRS(ph)PSTLLPK ddPTM_PC-9_AZD4547_30min_R2 2 TTTAAAVASTGPSSRSPSTLLPK 23 1 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 T(0.001)T(0.001)TAAAVAS(0.032)T(0.032)GPS(0.02)S(0.123)RS(0.386)PS(0.203)T(0.203)LLPK;TTTAAAVAS(0.15)T(0.15)GPS(0.166)S(0.166)RS(0.207)PS(0.081)T(0.081)LLPK 59.661 0.0027375 172976000.0 51173.0 19969.7 83399.0 194342.0 149442.0 70946.0 51520.0 72636.0 53804.0 95092.0 True False 67444.94953547695 26424.514996232283 82293.07476806144 149539.45445396882 128694.55785668916 66509.73540464499 56105.180192535205 61411.775209230545 56647.969596956966 91762.85802375228 0.7349918146405076 0.28796525702580505 0.896801565909819 1.629629434768274 1.4024689359978013 0.7248001733711186 0.6114149166759029 0.6692443602109087 0.6173300485289371 1.0 16.485622705433293 -10.67418406086429 4.680539296323863 1.0000158410804139 0.8513607107447128 0.015235439840314058 0.3746961143394887 322431420339.8809 58467195651.16728 56856982.36613138 0.10273996714277854 2.117463530547332e-11 10.67418406086429 -0.1486551303357011 TTTAAAVASTGPSSRS(ph)PSTLLPK ddPTM_PC-9_Lapatinib_30min_R1 2 TTTAAAVASTGPSSRSPSTLLPK 23 1 E7EVA0;P27816-4;H7C4C5;H0Y2V1;B5MEG9;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 TTTAAAVAS(0.002)T(0.002)GPS(0.008)S(0.043)RS(0.883)PS(0.032)T(0.032)LLPK;TTTAAAVAS(0.001)T(0.004)GPS(0.01)S(0.144)RS(0.695)PS(0.073)T(0.073)LLPK 93.26899999999999 5.8644e-06 87497000.0 248100.0 72023.0 165040.0 128795.0 88680.0 84228.0 62369.0 45441.0 134674.0 61361.0 True False 244562.04850403275 71856.23516858005 151471.04827282362 138267.01394752524 83464.01675158806 80625.76478505791 65598.16164613915 47552.35475052632 119505.59593990918 71967.1670916069 3.3982447605965937 0.9984585759380297 2.104724340198307 1.9212513085519312 1.1597513161154007 1.1203131656193928 0.9115012344815429 0.6607506821825708 1.660557178633844 1.0 16.135051248915854 -1.5228787452803376 0.6331292601231407 1.126583664116173 147.45834902809335 0.579393375477461 0.5016875630879498 155.5233862558962 1.0694166049198448 0.21740373652970849 31769.698588260795 0.029999999999999995 1.5228787452803376 146.33176536397718 TTTPGPS(ph)LSQGVSVDEK ddPTM_PC-9_AZD4547_30min_R2 1 TTTPGPSLSQGVSVDEK 17 0 A0A0C4DG07;O60934 A0A0C4DG07 NBN Nibrin 1 TTT(0.001)PGPS(0.901)LS(0.066)QGVS(0.031)VDEK 112.74 0.00023999 9701800.0 28271.0 26011.0 30536.0 32021.0 32862.0 29603.0 24775.0 25709.0 25955.0 30011.0 True False 37260.58992666972 34418.54707717181 30131.072688132055 24639.053169518378 28299.678539410106 27751.91973026961 26979.927004465448 21736.26478404798 27326.92831181731 28960.32402463748 1.286608184872895 1.1884724441581125 1.0404259518125067 0.8507865156673365 0.9771879111343733 0.9582737992385775 0.9316168901118909 0.7505532315714506 0.9435988453916957 1.0 14.821790123756564 -5.301784444916072 1.908311194384822 0.9097544603065073 1.2809614939399319 0.7713017852406006 0.06985709707853263 0.1764890177515339 1.1585252984213785 0.02037962172606628 0.07837396603524431 4.991321622143901e-06 5.301784444916072 0.37120703363342455 TTTPGPSLS(ph)QGVSVDEK ddPTM_PC-9_AZD4547_30min_R2 1 TTTPGPSLSQGVSVDEK 17 0 A0A0C4DG07;O60934 A0A0C4DG07 NBN Nibrin 1 TTTPGPS(0.076)LS(0.69)QGVS(0.234)VDEK 84.208 0.0034439999999999996 8417800.0 28135.0 23780.0 32453.0 39495.0 26921.0 37821.0 36216.0 32910.0 22476.0 36186.0 True False 37081.344755645485 31466.419956754664 32022.652015586486 30390.037941667295 23183.4838402854 35456.04689114372 39439.1538403116 27824.51569656615 23664.03547433659 34919.1391541612 1.0619203581147452 0.901122442275468 0.9170515880764617 0.8702974551434728 0.6639191114630527 1.0153757437894495 1.1294423286380404 0.7968270802360371 0.6776809522670212 1.0 15.09173037284295 -4.444018739043168 1.7747498199571436 0.881053620231209 1.3140963123849325 0.12791000387168805 0.13821068828592936 6.2353838120311345 9.145726168945776 0.039636757433601455 6.099601290204964 3.597338129394462e-05 4.444018739043168 0.4330426921537235 TTTPGPSLS(ph)QGVSVDEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTTPGPSLSQGVSVDEK 17 0 A0A0C4DG07;O60934 A0A0C4DG07 NBN Nibrin 1 TTTPGPS(0.009)LS(0.991)QGVSVDEK 171.25 2.0884999999999997e-24 0.0 13373.0 16714.0 23000.0 25192.0 24886.0 20242.0 20607.0 24363.0 18186.0 17063.0 True False 15636.784771210367 18373.255461022145 23548.40722798572 23780.573913565968 20009.766945645762 19180.47388599555 18654.95577823978 23723.49706473225 18451.935845468182 20156.386829366314 0.7757732029844142 0.9115351683097149 1.1682851409498398 1.1798034099504129 0.9927258846061171 0.9515829423382105 0.9255109031277835 1.176971709541163 0.915438664760349 1.0 14.298949428579064 -4.99262804923065 4.6084726614843285 1.0418519169328584 0.7957414151920404 0.4191237596598537 0.09794996265916354 0.17625590690382476 9.982660050153765 0.02589848060842804 0.10042085910167554 1.0171194301503704e-05 4.99262804923065 -0.24611050174081794 TTTPGPSLS(ph)QGVSVDEK ddPTM_PC-9_Lapatinib_30min_R1 1 TTTPGPSLSQGVSVDEK 17 0 A0A0C4DG07;O60934 A0A0C4DG07 NBN Nibrin 1 TTTPGPS(0.014)LS(0.493)QGVS(0.493)VDEK 99.37100000000001 0.0012642999999999999 9659900.0 40704.0 35974.0 41744.0 35102.0 36180.0 33841.0 25958.0 31344.0 30199.0 26452.0 True False 40123.55349580058 35890.704413235966 38311.96945649986 37683.51817683935 34051.96353261681 32393.699317224004 27301.978226530515 32800.356666897685 26797.67061043202 31024.192954925555 1.2932988636995428 1.1568618228161767 1.2349062395325665 1.214649426387626 1.0975938546440271 1.0441431744667196 0.880022189979189 1.0572509239661023 0.8637668882915288 1.0 14.921106060974525 -6.630029447850798 1.5693526729855642 0.9542588589027321 1.225067853561704 0.7942145389312659 0.06230034413305088 0.1599354110198492 0.8133191063500377 0.02422966331857802 0.024473154583360936 2.344069867502477e-07 6.630029447850798 0.2708089946589718 TTTPGPSLSQGVS(ph)VDEK ddPTM_PC-9_Lapatinib_30min_R1 1 TTTPGPSLSQGVSVDEK 17 0 A0A0C4DG07;O60934 A0A0C4DG07 NBN Nibrin 1 TTTPGPS(0.019)LS(0.404)QGVS(0.577)VDEK 149.74 5.9785e-05 7976800.0 55867.0 51680.0 61976.0 55473.0 51409.0 44861.0 46396.0 46181.0 54788.0 39205.0 True False 55070.326335246966 51560.33813520976 56880.57251427836 59552.6694725032 48385.223693982814 42942.399606098676 48798.15786262849 48326.73785202915 48617.198496782985 45981.53201262119 1.197661842152868 1.1213271041307906 1.2370308257381586 1.2951432208947922 1.0522751543098183 0.9339053686665264 1.0612555895100273 1.0510032123062851 1.0573201102442247 1.0 15.488766914117734 -6.386383550779152 6.212603828436419 1.0231674715562942 1.207258552591805 0.7495840743856974 0.053061696449604484 0.12949572457705624 6.023084499946777 0.017605277416419568 0.019960839693624888 4.1078677110786374e-07 6.386383550779152 0.18409108103551075 TTTS(ph)PFFSEDTFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TTTSPFFSEDTFR 13 0 A0A494C0H4;H0Y9M2;Q17R98-2;Q17R98;A0A5F9ZGT0;H0Y9K9;G5E9Z1;A0A590UJE4;Q17R98-3;A0A5F9ZHK5 A0A494C0H4 ZNF827 Zinc finger protein 827 1 T(0.016)T(0.011)T(0.094)S(0.846)PFFS(0.03)EDT(0.003)FR 112.5 0.00044864 6593300.0 25680.0 33733.0 32984.0 30647.0 36525.0 32162.0 32545.0 31318.0 29934.0 23829.0 True False 30027.116796880448 37081.789306369516 33770.463652516606 28929.94794891458 29368.188446906355 30475.36810203482 29462.101994604433 30495.935684163902 30371.728120435728 28149.009069739775 1.0667202075386604 1.3173390656309991 1.1997034626991507 1.027743032702857 1.043311626855 1.0826444379101032 1.0466479271654445 1.083375105980092 1.0789626038056657 1.0 14.780796515519775 -5.752809143626743 24.076502399348573 1.056001387154093 1.2068628311069323 0.5259495265782206 0.06169749624759193 84.31982363915624 235229.9516595332 0.01595472112243433 0.02705628900685802 1.7668140995959884e-06 5.752809143626743 0.1508614439528393 TTTS(ph)PFFSEDTFR ddPTM_PC-9_Lapatinib_30min_R1 2 TTTSPFFSEDTFR 13 0 A0A494C0H4;H0Y9M2;Q17R98-2;Q17R98;A0A5F9ZGT0;H0Y9K9;G5E9Z1;A0A590UJE4;Q17R98-3;A0A5F9ZHK5 A0A494C0H4 ZNF827 Zinc finger protein 827 1 T(0.01)T(0.01)T(0.044)S(0.915)PFFS(0.022)EDTFR;TTT(0.071)S(0.929)PFFSEDTFR 190.85 1.4422e-05 15409100.0 104069.0 85077.0 122498.0 99541.0 97041.0 87603.0 83964.0 96149.0 104585.0 75754.0 True False 102584.95697608264 84880.00943361517 112426.68729595447 106861.57719904179 91333.23916994657 83856.42390256711 88311.24508099268 100616.43354918128 92805.5359711259 88847.97796413994 1.1546121738131971 0.9553397992678428 1.2653826217781925 1.2027463049544285 1.0279720626485132 0.9438191596933418 0.9939589746953624 1.1324560879684986 1.0445430284140318 1.0 16.43905132277805 -6.287828539525578 21.640072928645775 1.0249240071580705 1.1396403284348238 0.32004733087588366 0.08608119035390828 192.63408024923228 157965.66991009895 0.028335044397057748 0.03214986343319367 5.154320982117191e-07 6.287828539525578 0.11471632127675324 TTTSPFFS(ph)EDTFR ddPTM_PC-9_AZD4547_30min_R2 1 TTTSPFFSEDTFR 13 0 A0A494C0H4;H0Y9M2;Q17R98-2;Q17R98;A0A5F9ZGT0;H0Y9K9;G5E9Z1;A0A590UJE4;Q17R98-3;A0A5F9ZHK5 A0A494C0H4 ZNF827 Zinc finger protein 827 1 TTT(0.001)S(0.149)PFFS(0.848)EDT(0.002)FR 99.844 0.0024043000000000003 10917000.0 24753.0 18343.0 37929.0 35524.0 32912.0 32428.0 22753.0 30647.0 32504.0 32444.0 True False 32623.939105615493 24272.016033084572 37426.03667763164 27334.490640328873 28342.736902472916 30400.2720336852 24777.97292159847 25911.21034799948 34222.09508176884 31308.145435185015 1.042027199380253 0.7752620187399208 1.1954089313629914 0.8730792022452268 0.9052831622092988 0.9710020063826738 0.7914225699792571 0.827618818931373 1.0930732116540205 1.0 14.934250431280427 TTWGDGGENS(ph)PCNVVSK ddPTM_PC-9_AZD4547_30min_R2 2 TTWGDGGENSPCNVVSK 17 0 H3BM38;H3BV99;H3BP15;H3BQY9;O00161 H3BM38 SNAP23 Synaptosomal-associated protein;Synaptosomal-associated protein 23 1 TTWGDGGENS(1)PCNVVSK;TTWGDGGENS(0.999)PCNVVS(0.001)K 144.08 3.4224e-05 31882000.0 145679.0 261610.0 217551.0 228503.0 212438.0 160854.0 218686.0 256223.0 174422.0 173912.0 True False 192001.8916885611 346170.3164376196 214666.13159470158 175825.16368615776 182944.65064680175 150795.77395172056 238148.63034908255 216629.6227688017 183641.59083042975 167823.39381469274 1.1440710816548363 2.062705970657786 1.2791192378800995 1.0476797047752497 1.090102199034335 0.8985384607239337 1.4190431079712376 1.2908189844378897 1.094255018065021 1.0 17.35658430933271 -5.507133068206692 24.037410443254807 1.1364081875563388 1.6202696544273636 0.3720630281011076 0.24763344797625336 393.70097778261595 601023.3741960077 0.06242582301449056 0.12383353712956564 3.110763050567364e-06 5.507133068206692 0.4838614668710248 TTWGDGGENS(ph)PCNVVSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTWGDGGENSPCNVVSK 17 0 H3BM38;H3BV99;H3BP15;H3BQY9;O00161 H3BM38 SNAP23 Synaptosomal-associated protein;Synaptosomal-associated protein 23 1 TTWGDGGENS(1)PCNVVSK;TTWGDGGENS(0.954)PCNVVS(0.046)K 152.66 1.3524000000000001e-05 11411000.0 48479.2 49567.5 44293.4 39555.0 62659.0 38447.2 36619.1 35309.8 30805.3 29552.7 True False 56685.77105215443 54488.23381980472 45349.52263965492 37338.861589040236 50381.4187513951 36430.9611495726 33150.27374867473 34382.955163825594 31255.769234598065 34910.370570955514 1.6237516280997446 1.5608036502808555 1.2990272488652554 1.0695635989640615 1.443164822584584 1.0435569876156563 0.949582407935104 0.9848922999525902 0.8953147366645836 1.0 15.091368050620646 -4.494102053258947 0.3590993951175955 0.9134492585912779 2.387254410084839 0.7813545502255514 0.12015316436329126 3.638886480111677 0.3202604882416068 0.11398588244791985 2.424171611412591 3.205515983615103e-05 4.494102053258947 1.473805151493561 TTWGDGGENS(ph)PCNVVSK ddPTM_PC-9_Lapatinib_30min_R1 2 TTWGDGGENSPCNVVSK 17 0 H3BM38;H3BV99;H3BP15;H3BQY9;O00161 H3BM38 SNAP23 Synaptosomal-associated protein;Synaptosomal-associated protein 23 1 TTWGDGGENS(0.981)PCNVVS(0.019)K;TTWGDGGENS(1)PCNVVSK 169.72 1.5675e-05 32715000.0 173628.0 209705.0 113209.0 88656.0 123939.0 81542.0 77005.0 73982.0 118706.0 52378.0 True False 171152.03288052435 209219.44095673706 103901.39301937725 95176.05798774626 116649.15169344915 78054.63874368607 80991.94211164115 77419.47380456924 105336.0802504038 61431.467510701994 2.786064533631854 3.4057373107729987 1.6913382868686404 1.5493046453947337 1.8988501564467375 1.2705970068204564 1.31841131904478 1.260257599919487 1.714692559347588 1.0 15.906690227202967 -5.338161326821022 4.919129754346968 1.4637623467316179 3.0931748661345093 0.8443473687566683 0.2813305307339162 0.07003168823281122 3.064079136052327 0.07338126553941024 0.16106097167416228 4.590274668109779e-06 5.338161326821022 1.6294125194028914 TTYDS(ph)AEEENKENLYAGK ddPTM_PC-9_AZD4547_30min_R2 2 TTYDSAEEENKENLYAGK 18 1 E7ESG2;Q9HAW4-2;Q9HAW4-3;Q9HAW4 E7ESG2 CLSPN Claspin 1 T(0.001)T(0.001)Y(0.004)DS(0.995)AEEENKENLYAGK;T(0.005)T(0.005)Y(0.004)DS(0.986)AEEENKENLYAGK 91.65700000000001 0.00057377 39150000.0 48875.0 43223.0 53070.0 35935.0 38769.0 46405.0 57326.0 52236.0 42881.0 48561.0 True False 64416.23333684639 57193.98947816683 52366.25712467801 27650.740940215557 33386.593551652055 43503.28801415942 62427.90294482282 44164.126463865985 45147.60211670346 46860.89417081804 1.3746266364878859 1.220505722099165 1.1174830965408329 0.5900600368277792 0.712461726187954 0.9283495072795789 1.3321961530921642 0.9424516378812201 0.9634387673468359 1.0 15.516096862634347 -5.383081332664972 3.243458484557766 0.9273109930692838 1.3052773405077933 0.38516145016229086 0.1872608769716477 0.28501091144852425 5.554094120647037 0.056445691808230655 0.13568027884973233 4.1392215013196585e-06 5.383081332664972 0.37796634743850954 TTYDS(ph)AEEENKENLYAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTYDSAEEENKENLYAGK 18 1 E7ESG2;Q9HAW4-2;Q9HAW4-3;Q9HAW4 E7ESG2 CLSPN Claspin 1 T(0.005)T(0.005)Y(0.01)DS(0.96)AEEENKENLY(0.02)AGK;T(0.02)T(0.02)Y(0.055)DS(0.903)AEEENKENLY(0.002)AGK 58.83 0.014402000000000002 13728300.0 27925.0 35630.0 29029.0 35440.0 33097.0 27626.0 36303.0 31542.0 21182.0 26313.0 True False 32652.15095610928 39167.110929533315 29721.16145309556 33454.411698030264 26611.880438802447 26177.24392720646 32864.11702904053 30714.055921511503 21491.74667759303 31083.33860640659 1.0504711662272772 1.2600676981802907 0.9561766137621307 1.07628115890791 0.8561461423361219 0.8421632006354384 1.057290448918087 0.9881195939222895 0.6914233683110014 1.0 14.923853848939418 -5.702181101156438 1.462128792241762 0.9139854858233148 1.1478010220606683 0.3487049414444675 0.11895088760728052 0.4733669886520409 2.0133214447598986 0.03833930242735534 0.09642077874851357 1.985266886798713e-06 5.702181101156438 0.2338155362373534 TTYDS(ph)AEEENKENLYAGK ddPTM_PC-9_Lapatinib_30min_R1 2 TTYDSAEEENKENLYAGK 18 1 E7ESG2;Q9HAW4-2;Q9HAW4-3;Q9HAW4 E7ESG2 CLSPN Claspin 1 T(0.009)T(0.004)Y(0.051)DS(0.935)AEEENKENLYAGK;T(0.042)T(0.006)Y(0.023)DS(0.929)AEEENKENLYAGK 66.673 0.0064784 50141000.0 83770.0 115542.0 122215.0 131074.0 147840.0 134002.0 115808.0 121902.0 126992.0 129009.0 True False 82575.42443846325 115274.46959787908 112166.95446354272 140713.61921004596 139144.34186462336 128271.04683391887 121803.97158710401 127566.01194513014 112688.82367495548 151308.03375631262 0.5457438206582879 0.761852934944175 0.7413152605247114 0.9299811498222932 0.919609741864207 0.847747760971531 0.8050066382018681 0.8430881611387541 0.7447643120949224 1.0 17.207129064454726 -4.458581071808395 1.1373684243703377 0.8574815645020057 0.18878432585610103 0.6263264439814094 0.07386839050587815 2.0429949020150797 1.3618687693123244 0.022653351295274068 1.944743352729955 3.478715627548457e-05 4.458581071808395 -0.6686972386459047 TTYLVLDEADR ddPTM_PC-9_AZD4547_30min_R2 3 TTYLVLDEADR 11 0 P17844-2;P17844;J3KTA4;J3QSF1;J3KRZ1 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 ;; 166.07 1.1133e-17 4655300.0 32241.5 31433.1 48362.9 59446.0 48240.2 43805.3 39282.2 51427.4 40196.2 41787.0 False True 42493.62633513928 41593.2348672273 47721.5763462425 45741.64313154457 41542.880916464324 41066.14766612776 42778.23970029515 43480.477014086515 42320.88906983127 40324.049848972885 1.0538035364575777 1.0314746416346556 1.183451972829511 1.1343514181453103 1.0302259091548684 1.0184033553161025 1.0608616907407373 1.078276541590825 1.0495198083609463 1.0 15.299352919270738 -6.273670273812393 24.559188826694584 1.0434701731108698 1.1017265237673897 0.3165010402860665 0.04383985902896398 861.8615536955249 1730584.1640638236 0.014724496804811249 0.01683763311007509 5.325124012826565e-07 6.273670273812393 0.058256350656519906 TTYLVLDEADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TTYLVLDEADR 11 0 P17844-2;P17844;J3KTA4;J3QSF1;J3KRZ1 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 ; 130.98 0.0012218 0.0 17329.4 16651.199999999997 18026.7 18664.2 20003.1 18190.3 19585.2 19550.2 18883.0 18992.4 False True 20262.92514874843 18304.2210920529 18456.524894640457 17618.505384152828 16083.63614845483 17236.368645806982 17729.948071431136 19037.027965149147 19159.12815187372 22435.57177624434 0.903160630396931 0.8158571252208568 0.8226456218148605 0.7852933528891824 0.7168810453712089 0.7682607253209176 0.7902605847649623 0.8485198485249348 0.853962107271104 1.0 14.453500331481726 -8.745546400486642 1.1850631600938524 0.999074792413214 0.7981811755501312 0.6229574531301812 0.04578884829876719 0.5709517325542809 1.5319261739581052 0.04741956266016911 0.014632987520279276 1.7966091182804676e-09 8.745546400486642 -0.2008936168630827 TTYLVLDEADR ddPTM_PC-9_Lapatinib_30min_R1 4 TTYLVLDEADR 11 0 P17844-2;P17844;J3KTA4;J3QSF1;J3KRZ1 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 ;;; 176.6 9.6695e-13 18181100.0 112932.0 105506.0 131378.0 100426.0 108499.0 120300.0 114703.0 97382.0 113258.0 93357.0 False True 111321.56897080754 105261.70733926933 120576.60797374566 107811.66305131528 102117.30213724135 115155.04943299698 120641.76009391055 101906.72323046904 100501.69138038701 109493.6330596167 1.0166944493493568 0.9613500292017602 1.1012202682880616 0.9846386501086724 0.9326323301523924 1.0517054390760583 1.1018152994176744 0.9307091232874083 0.9178770360616879 1.0 16.740487455492698 -7.821652971750321 24.999970053888287 0.9432193765361119 1.0185286089091299 0.25810872290129583 0.05540540168650108 103.79219987253474 43091.42757367979 0.03099826924823698 0.014891092517169116 1.507811419867186e-08 7.821652971750321 0.07530923237301801 TVAGQDAVIVLLGTR ddPTM_PC-9_Lapatinib_30min_R1 3 TVAGQDAVIVLLGTR 15 0 A0A2R8YEP4;P30043;M0R192;A0A2R8Y7Y9;M0QZL1 A0A2R8YEP4 BLVRB Flavin reductase (NADPH) 0 ;; 128.96 7.5954e-05 23238000.0 32298.5 26976.96 34626.8 33319.13 38247.3 34196.9 33777.2 37150.91 32477.05 37723.6 False True 31837.917467180523 26914.496506579468 31779.91816731338 35769.52996955936 35997.669011084974 32734.378303867397 35526.018142891095 38877.07690466485 28819.142630502036 44244.07399646262 0.7195973288925882 0.6083186758238249 0.7182864346952822 0.8084592294194967 0.8136156045205747 0.7398590443204792 0.8029554002131778 0.8786956849356398 0.6513672911948879 1.0 15.433196614667347 -14.522878745279929 0.0785518135928734 1.7396383984139006 0.5198167164511445 0.4999310161548497 0.07594950848299724 220.54413429855296 1.2251681156438956 29.08432256965037 2.8141956765922607 3.0000000000028236e-15 14.522878745279929 -1.219821681962756 TVAISDAAQLPHDY(ph)CTTPGGTLFSTT(ph)PGGTR ddPTM_PC-9_AZD4547_30min_R2 1 TVAISDAAQLPHDYCTTPGGTLFSTTPGGTR 31 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 2 TVAIS(0.004)DAAQLPHDY(0.417)CT(0.235)T(0.246)PGGT(0.178)LFS(0.108)T(0.11)T(0.582)PGGT(0.12)R 48.132 0.030458 73486000.0 70977.0 80386.0 89099.0 98753.0 79656.0 125720.0 94454.0 105770.0 83348.0 94068.0 True False 93546.20958668726 106369.20246609247 87917.4890437477 75987.02156864083 68597.13936264519 117858.70852580808 102860.2230183564 89425.6768528048 87753.6051216856 90774.7079520708 1.0305316502486552 1.171793386790686 0.9685240638853752 0.837094641039904 0.7556855969050827 1.2983650532705395 1.133137471206922 0.9851386897330664 0.9667186719897755 1.0 16.470002763024098 -6.756944755262303 24.99950465856425 1.0792722218252802 0.9593500605944238 0.17064801995633205 0.1361710338466716 248.91093867747097 1384465.3449974845 0.050677830116437665 0.04902796050302975 1.7500692932721678e-07 6.756944755262303 -0.1199221612308563 TVAISDAAQLPHDY(ph)CTTPGGTLFSTT(ph)PGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVAISDAAQLPHDYCTTPGGTLFSTTPGGTR 31 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 2 TVAISDAAQLPHDY(0.955)CT(0.094)T(0.1)PGGT(0.027)LFS(0.11)T(0.11)T(0.458)PGGT(0.146)R 97.609 3.581e-12 8223400.0 17940.0 20429.0 24778.0 23958.0 34245.0 31079.0 27838.0 29218.0 28763.0 22396.0 True False 20976.887668848725 22457.05610944247 25368.80149108828 22615.710932884005 27534.938079789397 29449.162528547382 25200.983110333334 28451.058459029977 29183.60446075007 26456.217513361535 0.7928906563553346 0.8488385045254744 0.9588975248739143 0.8548353868598976 1.0407738016926669 1.1131282283143566 0.9525542756671753 1.0754015930153644 1.1030905852664346 1.0 14.69131919155179 -5.701794277192164 0.7568246865272386 1.057757026530183 0.782118213531762 0.6779158622499195 0.06080523315607657 0.6166350796599273 0.5930848977416896 0.029939411030570406 0.11800575456996992 1.9870359420020108e-06 5.701794277192164 -0.27563881299842097 TVAISDAAQLPHDY(ph)CTTPGGTLFSTTPGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVAISDAAQLPHDYCTTPGGTLFSTTPGGTR 31 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 1 TVAISDAAQLPHDY(0.454)CT(0.078)T(0.337)PGGT(0.078)LFS(0.022)T(0.022)T(0.007)PGGT(0.002)R 67.46300000000001 0.0086069 0.0 12052.0 8001.0 14823.0 11749.0 12285.0 6873.7 6363.6 5427.4 5824.6 7413.7 True False 14092.165562149641 8795.28640323312 15176.436536540545 11090.741620771938 9877.842438610387 6513.2310715427175 5760.793739525725 5284.936500805639 5909.773755939398 8757.745123183093 1.6091088932064854 1.004286637658665 1.7329159872860644 1.2663923720973618 1.127897912039279 0.7437109644012357 0.6577941762972779 0.6034585873954704 0.674805406279217 1.0 13.096343748283381 -6.568270001764509 2.0091420981693626 0.6949666718860514 1.4045826468011529 0.6990537668602407 0.20698733844030298 0.17282636496912654 1.4148605693382568 0.07409777926093888 0.07771997883697467 2.7022778301329313e-07 6.568270001764509 0.7096159749151014 TVAISDAAQLPHDYCT(ph)T(ph)PGGTLFSTTPGGTR ddPTM_PC-9_AZD4547_30min_R2 4 TVAISDAAQLPHDYCTTPGGTLFSTTPGGTR 31 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 2 TVAISDAAQLPHDY(0.188)CT(0.71)T(0.71)PGGT(0.186)LFS(0.09)T(0.09)T(0.025)PGGTR;TVAISDAAQLPHDY(0.098)CT(0.889)T(0.889)PGGT(0.038)LFS(0.027)T(0.027)T(0.027)PGGT(0.005)R;TVAISDAAQLPHDY(0.356)CT(0.513)T(0.341)PGGT(0.277)LFS(0.122)T(0.122)T(0.186)PGGT(0.083)R;TVAISDAAQLPHDY(0.002)CT(0.709)T(0.741)PGGT(0.044)LFS(0.107)T(0.096)T(0.28)PGGT(0.021)R 90.37 3.5486999999999995e-09 15094700.0 25434.8 25279.9 40192.7 48698.3 46244.0 40728.8 33306.200000000004 45200.4 34368.6 36976.799999999996 True False 33522.53732329451 33451.133299611545 39659.71853655633 37471.659316234865 39823.81882954417 38182.02169747002 36270.38727734115 38215.7167818617 36185.254031112454 35682.253486861955 0.9394736612035268 0.9374725537423835 1.1114689981998715 1.0501483413885775 1.1160679311974262 1.0700563435974826 1.0164825293530226 1.0710006529137113 1.0140966585654603 1.0 15.12291911004472 -5.245667208347397 24.570530299538945 1.0597042904869067 0.9384730700368332 0.6169588832500854 0.037009886968618684 395.6458556480982 616350.2093941798 0.009222930931454555 0.024206383464644234 5.6797967078204304e-06 5.245667208347397 -0.1212312204500735 TVAISDAAQLPHDYCT(ph)T(ph)PGGTLFSTTPGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TVAISDAAQLPHDYCTTPGGTLFSTTPGGTR 31 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 2 TVAISDAAQLPHDY(0.006)CT(0.921)T(0.921)PGGT(0.085)LFS(0.021)T(0.021)T(0.021)PGGT(0.002)R;TVAISDAAQLPHDY(0.273)CT(0.646)T(0.646)PGGT(0.095)LFS(0.098)T(0.098)T(0.111)PGGT(0.034)R;TVAISDAAQLPHDY(0.262)CT(0.506)T(0.547)PGGT(0.067)LFS(0.275)T(0.163)T(0.163)PGGT(0.017)R;TVAISDAAQLPHDY(0.052)CT(0.682)T(0.682)PGGT(0.077)LFS(0.166)T(0.166)T(0.166)PGGT(0.009)R 88.186 9.967700000000001e-08 3183100.0 20387.41 18799.1 24936.4 28853.899999999998 36573.6 29797.4 32687.8 29816.5 27912.1 21744.3 True False 23838.595843297837 20665.350409076316 25530.978347823635 27237.309528605947 29407.265625784385 28234.771888675223 29591.37494482196 29033.848468193133 28320.261657994717 25686.369462215924 0.928064041061306 0.8045259350284821 0.9939504446270281 1.0603798862533462 1.1448587808036406 1.0992122467991416 1.1520263690184092 1.130321220011309 1.102540462156522 1.0 14.648715372201783 -5.6014754830924876 2.2722622575354277 1.1115630901843356 0.8660912878848064 0.7638636968013012 0.051244976182511885 0.12201341736850597 1.2628853316863862 0.013882575730500614 0.030624554718926996 2.503366965131531e-06 5.6014754830924876 -0.24547180229952925 TVAISDAAQLPHDYCT(ph)T(ph)PGGTLFSTTPGGTR ddPTM_PC-9_Lapatinib_30min_R1 2 TVAISDAAQLPHDYCTTPGGTLFSTTPGGTR 31 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 2 TVAISDAAQLPHDY(0.008)CT(0.405)T(0.802)PGGT(0.194)LFS(0.194)T(0.194)T(0.194)PGGT(0.007)R;TVAISDAAQLPHDY(0.015)CT(0.609)T(0.609)PGGT(0.471)LFS(0.131)T(0.131)T(0.028)PGGT(0.004)R 101.43 7.259e-13 48997200.0 29825.0 37690.0 45728.0 41917.0 53913.0 58696.0 51611.0 54816.0 73220.0 41146.0 True False 29399.69003076486 37602.73112066668 41968.42035518459 44999.716011012875 50741.94333703618 56185.70890705884 54283.165045437556 57362.951475646485 64973.192559218216 48258.03127640125 0.6092185953955743 0.7792015158118326 0.8696670635983372 0.9324813885024413 1.051471475212243 1.1642768554989587 1.1248524568797043 1.1886716046723118 1.3463705592770603 1.0 15.55848144044693 -5.541458022339169 0.6310455384929589 1.1969062655908953 0.5267582480179193 0.829811887460036 0.08488306553942822 0.592840921201699 0.3332177116216308 0.04621396268622866 0.25446115212287485 2.8743654081167896e-06 5.541458022339169 -0.670148017572976 TVAISDAAQLPHDYCT(ph)TPGGT(ph)LFSTTPGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVAISDAAQLPHDYCTTPGGTLFSTTPGGTR 31 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 2 TVAISDAAQLPHDY(0.306)CT(0.346)T(0.346)PGGT(0.388)LFS(0.188)T(0.188)T(0.188)PGGT(0.049)R;TVAISDAAQLPHDY(0.074)CT(0.479)T(0.479)PGGT(0.252)LFS(0.216)T(0.216)T(0.216)PGGT(0.065)R 64.70100000000001 0.0019705 14841000.0 6996.200000000001 11806.6 10993.1 8750.5 11774.2 9108.6 11871.8 9268.8 8748.8 8820.4 True False 8180.518478751358 12978.6812208989 11255.217195563915 8260.237854503774 9467.130031801911 8630.928981226121 10747.21715961114 9025.503821105372 8876.73464889651 10419.468697752014 0.7851185809998444 1.245618332122734 1.080210279627042 0.7927695829909166 0.9086000741903886 0.8283463611813751 1.0314553909960724 0.8662153592392492 0.8519373594175348 1.0 13.346994094146615 -5.742913930620765 24.986845029440705 0.8946912253485287 1.0578460626339328 0.20157664014288068 0.12552097818049557 325.655120919516 439235.2643654286 0.03261600728886781 0.0563627149552162 1.8075323110110788e-06 5.742913930620765 0.16315483728540403 TVAISDAAQLPHDYCT(ph)TPGGT(ph)LFSTTPGGTR ddPTM_PC-9_Lapatinib_30min_R1 3 TVAISDAAQLPHDYCTTPGGTLFSTTPGGTR 31 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 2 TVAISDAAQLPHDY(0.139)CT(0.453)T(0.409)PGGT(0.506)LFS(0.171)T(0.171)T(0.134)PGGT(0.016)R;TVAISDAAQLPHDY(0.085)CT(0.464)T(0.464)PGGT(0.23)LFS(0.248)T(0.247)T(0.255)PGGT(0.008)R;TVAISDAAQLPHDY(0.028)CT(0.485)T(0.485)PGGT(0.518)LFS(0.139)T(0.197)T(0.141)PGGT(0.006)R 82.94200000000001 2.0836e-07 41232000.0 28718.2 33311.3 42594.700000000004 37997.1 48667.399999999994 58683.4 50444.7 50698.6 51245.200000000004 43347.5 True False 28308.673201727106 33234.16973149017 39092.72818629683 40791.53348860982 45804.879215789806 56173.64777968684 53056.47973818723 53054.24204033879 45473.425940120906 50840.057618086896 0.5568182753525439 0.6537004733776454 0.7689355602222837 0.8023502607931309 0.9009604111757386 1.1049092076501201 1.04359597970463 1.0435519652413645 0.8944408812775075 1.0 15.633678044929322 -5.77579506165734 0.9397428803331761 1.022021799846362 0.5640816818836403 0.8705126940084359 0.06160296340500357 0.24324593688915847 0.4011363015936656 0.02697652271512397 0.08297728476209666 1.6757334479407658e-06 5.77579506165734 -0.4579401179627218 TVAISDAAQLPHDYCT(ph)TPGGTLFS(ph)TTPGGTR ddPTM_PC-9_AZD4547_30min_R2 1 TVAISDAAQLPHDYCTTPGGTLFSTTPGGTR 31 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 2 TVAISDAAQLPHDY(0.282)CT(0.394)T(0.394)PGGT(0.098)LFS(0.276)T(0.276)T(0.276)PGGT(0.003)R 63.703 0.0011152 3354400.0 6032.1 5405.8 7596.8 7416.3 8651.6 7403.2 4313.5 8815.2 6865.1 6109.4 True False 7950.182324525648 7153.119133819359 7496.061468339058 5706.5866156928 7450.474677486471 6940.276733680098 4697.3931436432595 7453.013393144031 7227.975170620575 5895.511765556635 1.348514368332368 1.2133160645374415 1.2714861349498645 0.9679544105114686 1.2637536780122127 1.1772136176925805 0.796774449859782 1.2641842963806456 1.226013187328129 1.0 12.525401337830546 -4.8532648336076045 0.8878877573220884 1.1061250020263043 1.4508327666566365 0.2170295894151999 0.14566459415212882 3.4703801292397496 2.2973350922281988 0.05311005258401766 1.1431003839049676 1.4019585268467363e-05 4.8532648336076045 0.34470776463033226 TVAISDAAQLPHDYCT(ph)TPGGTLFS(ph)TTPGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVAISDAAQLPHDYCTTPGGTLFSTTPGGTR 31 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 2 TVAISDAAQLPHDY(0.037)CT(0.491)T(0.491)PGGT(0.208)LFS(0.344)T(0.344)T(0.08)PGGT(0.004)R 63.713 0.0011051 6837700.0 10493.0 10007.0 15424.0 16999.0 18401.0 17078.0 19810.0 19954.0 18712.0 14847.0 True False 12269.257653803204 11000.428826040968 15791.766655845731 16046.601141501584 14795.456142683754 16182.399615899221 17933.453388020094 19430.2286430106 18985.627600373948 17538.643571212666 0.6995556756704691 0.627210923203702 0.9003984026316494 0.9149282882879227 0.8435918138486213 0.922671103394818 1.0225108524045414 1.1078524153887657 1.0825026190472513 1.0 14.098249554426957 -5.3200114505928235 0.41962143152527076 1.0769399699162834 0.46768727373087654 0.7900699052260198 0.06773648186791435 1.609147447528763 0.3105444236611587 0.06079687838713184 0.4701127754967092 4.786174729450532e-06 5.3200114505928235 -0.6092526961854068 TVAISDAAQLPHDYCT(ph)TPGGTLFSTT(ph)PGGTR ddPTM_PC-9_AZD4547_30min_R2 1 TVAISDAAQLPHDYCTTPGGTLFSTTPGGTR 31 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 2 TVAISDAAQLPHDY(0.045)CT(0.685)T(0.407)PGGT(0.074)LFS(0.047)T(0.233)T(0.5)PGGT(0.008)R 86.45 7.5395e-09 75039000.0 39655.0 44249.0 60560.0 75267.0 64237.0 70840.0 40319.0 59709.0 51027.0 59867.0 True False 52264.46512475995 58551.623913643285 59756.93483079895 57915.35601355792 55318.8013613318 66410.36360140175 43907.31289174741 50482.34602632238 53724.18304631484 57771.07455209662 0.9046822398574057 1.013511075700051 1.0343746467258719 1.0024974688904424 0.9575518854413307 1.1495435062665214 0.7600224373904073 0.8738342919482753 0.929949519943023 1.0 15.818059708857286 -7.266976278621488 24.999987633653365 0.8804377630264906 1.0088371604097042 0.3408963652036826 0.08079661016202476 506.1767821690866 2285457.9572781073 0.0321689784582827 0.02238590749193624 5.4078386001970424e-08 7.266976278621488 0.1283993973832136 TVAISDAAQLPHDYCT(ph)TPGGTLFSTT(ph)PGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVAISDAAQLPHDYCTTPGGTLFSTTPGGTR 31 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 2 TVAISDAAQLPHDY(0.012)CT(0.723)T(0.309)PGGT(0.065)LFS(0.207)T(0.177)T(0.498)PGGT(0.008)R 121.36 1.9702e-17 46002000.0 9647.5 13646.0 14830.0 16982.0 22673.0 16467.0 23484.0 21376.0 14771.0 15238.0 True False 11280.631203189407 15000.684696727796 15183.603443088188 16030.553596386848 18230.388409492352 15603.441531503258 21259.42551056353 20814.902649744145 14986.997931013437 18000.52877605838 0.6266833237806447 0.8333468912690759 0.8435087453254791 0.8905601494167382 1.0127696045096017 0.8668323984046863 1.181044500139332 1.1563495111004196 0.8325865377325419 1.0 14.135751666737304 -4.0706847134675845 0.4712715988104746 1.0396038804686956 0.0356996095684964 0.5536591365792569 0.10553872067249506 6.793199682116212 0.7028763736309548 0.06839880417523758 4.361248359148257 8.497971818710678e-05 4.0706847134675845 -1.003904270900199 TVAISDAAQLPHDYCT(ph)TPGGTLFSTTPGGTR ddPTM_PC-9_Lapatinib_30min_R1 1 TVAISDAAQLPHDYCTTPGGTLFSTTPGGTR 31 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 1 TVAISDAAQLPHDY(0.005)CT(0.442)T(0.442)PGGT(0.092)LFS(0.008)T(0.008)T(0.003)PGGT(0.001)R 90.706 6.0138e-09 5679800.0 25896.0 28293.0 37898.0 21536.0 20947.0 22297.0 15758.0 16259.0 15392.0 11671.0 True False 25526.7182912552 28227.489296816726 34782.17273051053 23119.82928198996 19714.938643386507 21343.409286845646 16573.872135513833 17014.4524963977 13658.390875054452 13688.31679937003 1.8648544350193592 2.0621592640313398 2.541011670047795 1.6890191555950833 1.4402748659567726 1.5592427907445803 1.2108042485016568 1.2429908472881592 0.9978137615636603 1.0 13.740657434290055 -6.517224740870137 0.8989647246415088 1.0988237025685583 2.1555946263013825 0.785812722897791 0.21660716059747226 0.275844257730754 0.4880713208976435 0.12630445867005288 0.15270871334362016 3.0393118204477416e-07 6.517224740870137 1.0567709237328242 TVAISDAAQLPHDYCTT(ph)PGGT(ph)LFSTTPGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVAISDAAQLPHDYCTTPGGTLFSTTPGGTR 31 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 2 TVAISDAAQLPHDY(0.08)CT(0.384)T(0.585)PGGT(0.78)LFS(0.047)T(0.044)T(0.078)PGGT(0.002)R 87.016 6.963199999999999e-09 6490900.0 18745.0 15301.0 18675.0 23360.0 30728.0 27142.0 26766.0 27616.0 23267.0 20343.0 True False 21918.158269373977 16819.982159213825 19120.282825331884 22051.21493414183 24707.068982793677 25718.625739239767 24230.530710941224 26891.10926157067 23607.235858160555 24031.02486490061 0.9120775494426516 0.6999277914185368 0.7956499122623235 0.9176144196142686 1.0281321384207998 1.0702259218583743 1.0083020115522419 1.1190163304623542 0.9823649216326584 1.0 14.552610556772143 -6.016274423764457 2.3967663470380423 1.0421025759393956 0.7911379238915986 0.747861894436824 0.06042485630700928 0.13048505229219748 1.5003385278849835 0.0180929995874336 0.02736338539982688 9.632201877955954e-07 6.016274423764457 -0.25096465204779694 TVAISDAAQLPHDYCTTPGGT(ph)LFSTTPGGTR ddPTM_PC-9_AZD4547_30min_R2 1 TVAISDAAQLPHDYCTTPGGTLFSTTPGGTR 31 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 1 TVAISDAAQLPHDY(0.023)CT(0.097)T(0.097)PGGT(0.211)LFS(0.211)T(0.211)T(0.075)PGGT(0.075)R 50.493 0.020068 5110700.0 5700.0 6385.2 9195.0 13386.0 11003.0 10622.0 6358.6 11467.0 5535.4 7145.4 True False 7512.481432634768 8449.09103060849 9073.068292093725 10300.064511638393 9475.423375604929 9957.804660842616 6924.503081759592 9695.03863544588 5827.989943256927 6895.241720890492 1.0895167619540047 1.2253509554292064 1.3158448477020144 1.4937931008904766 1.3741974189095167 1.4441559939332491 1.0042437034194822 1.4060476815588427 0.8452190915366875 1.0 12.751385412676521 -8.264361048497042 24.994822691553793 0.9226095071914607 1.2972345828653622 0.4958636798087651 0.1498223187631644 223.00335609076697 1907734.899776991 0.12770482092854096 0.03853116103079363 5.440501714560522e-09 8.264361048497042 0.37462507567390146 TVAISDAAQLPHDYCTTPGGT(ph)LFSTTPGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVAISDAAQLPHDYCTTPGGTLFSTTPGGTR 31 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 1 TVAISDAAQLPHDYCT(0.017)T(0.093)PGGT(0.317)LFS(0.19)T(0.19)T(0.19)PGGT(0.002)R;TVAISDAAQLPHDY(0.004)CT(0.015)T(0.015)PGGT(0.494)LFS(0.088)T(0.088)T(0.254)PGGT(0.042)R 105.64 7.363200000000001e-15 49687000.0 61801.0 66368.0 90253.0 87712.0 83144.0 55587.0 53498.0 38951.0 42640.0 40544.0 True False 72262.68867461101 72956.5764291681 92404.97380640869 82797.78100614074 66852.53005419811 52671.91986467915 48430.28214802115 37928.57752199588 43263.52933304536 47894.306253872586 1.508794976412631 1.523282872967161 1.9293519633962148 1.728760420231496 1.395834605053761 1.099753268905952 1.011190806090969 0.7919224744784583 0.9033125796565266 1.0 15.547566535979607 -6.722449528796683 1.8086197282748633 0.9103763369799729 1.6801175868206266 0.8803412340578948 0.12522040447862523 0.11797048843441905 0.7968795050443714 0.0558488217136325 0.052550988118135765 1.894743697761677e-07 6.722449528796683 0.7697412498406537 TVAISDAAQLPHDYCTTPGGTLFSTT(ph)PGGTR ddPTM_PC-9_AZD4547_30min_R2 3 TVAISDAAQLPHDYCTTPGGTLFSTTPGGTR 31 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 1 TVAISDAAQLPHDYCT(0.004)T(0.001)PGGT(0.016)LFS(0.084)T(0.215)T(0.554)PGGT(0.126)R;TVAISDAAQLPHDYCTTPGGT(0.015)LFS(0.043)T(0.161)T(0.62)PGGT(0.161)R;TVAISDAAQLPHDYCT(0.011)T(0.004)PGGT(0.013)LFS(0.204)T(0.204)T(0.558)PGGT(0.005)R 117.94 6.999100000000001e-17 59118000.0 120546.0 138019.0 178519.0 275948.0 217587.0 151649.0 114056.0 196747.0 134024.0 148141.0 True False 158877.1204874373 182630.94264135096 176151.7214177575 212332.4519541006 187378.80087501154 142166.36405687442 124206.76304425058 166344.27194628707 141108.23502458105 142954.62868061106 1.1113814358708192 1.277544800940896 1.2322211812484598 1.4853135845534133 1.3107571444479273 0.9944859104527648 0.8688544343796876 1.1636158512777723 0.9870840582563072 1.0 17.12519780770735 -6.762541596062153 24.999091140363216 1.0046619010815592 1.2914852497766083 0.6244064885253535 0.10873320008202146 20.332414768898943 461146.32105383987 0.0386992668024209 0.03606354574115282 1.7276604998993274e-07 6.762541596062153 0.2868233486950491 TVAISDAAQLPHDYCTTPGGTLFSTT(ph)PGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVAISDAAQLPHDYCTTPGGTLFSTTPGGTR 31 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 1 TVAISDAAQLPHDYCTT(0.001)PGGT(0.098)LFS(0.229)T(0.157)T(0.431)PGGT(0.084)R;TVAISDAAQLPHDY(0.004)CT(0.009)T(0.03)PGGT(0.169)LFS(0.169)T(0.169)T(0.395)PGGT(0.054)R 116.4 8.4901e-17 51328000.0 115827.0 112145.0 142764.0 155244.0 131770.0 91856.0 83560.0 74440.0 66387.0 68844.0 True False 135434.22341247142 123278.01445951492 146168.03519548487 146546.18198783862 105950.61441885961 87038.90965675359 75644.59187798885 72486.02887569963 67357.78428313514 81324.87223119567 1.6653481240948051 1.5158709885095438 1.7973349503697813 1.8019847798989164 1.3028070196981838 1.070261867849158 0.9301532213040735 0.8913143898908517 0.8282556422793512 1.0 16.31140903021192 -6.613126184932287 2.0748818244821434 0.9143471471278342 1.6896493981698093 0.9325121776138928 0.09526265957093537 0.07913490994743567 0.6946818949187773 0.038306419255768824 0.03892882414863243 2.437102611561662e-07 6.613126184932287 0.7753022510419751 TVAISDAAQLPHDYCTTPGGTLFSTT(ph)PGGTR ddPTM_PC-9_Lapatinib_30min_R1 4 TVAISDAAQLPHDYCTTPGGTLFSTTPGGTR 31 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 1 TVAISDAAQLPHDYCTT(0.001)PGGT(0.066)LFS(0.188)T(0.188)T(0.542)PGGT(0.015)R;TVAISDAAQLPHDY(0.052)CT(0.012)T(0.014)PGGT(0.214)LFS(0.18)T(0.152)T(0.3)PGGT(0.077)R;TVAISDAAQLPHDYCT(0.002)T(0.002)PGGT(0.144)LFS(0.144)T(0.108)T(0.405)PGGT(0.194)R;TVAISDAAQLPHDYCTT(0.002)PGGT(0.071)LFS(0.171)T(0.171)T(0.574)PGGT(0.011)R 136.91 4.578e-17 80240000.0 195665.0 194031.0 240615.0 153527.0 168440.0 133965.0 115914.0 132581.0 110322.0 89769.0 True False 192874.7812194331 193581.7331407292 220832.5635007593 164817.88773105812 158532.69036578157 128235.62923766763 121915.45974844201 138741.1972707364 97896.3746178377 105285.45204032627 1.8319224307035171 1.8386370518367896 2.097465121925642 1.5654383823885738 1.5057416508508756 1.21798051632576 1.1579516199611903 1.3177622794229533 0.9298186285066391 1.0 16.683946578233957 -6.413180711595244 1.1195343496008399 1.1075882147848843 1.922394788160073 0.8662538849013912 0.13497290666808986 0.1672538624819298 0.4404025481192137 0.06045737210384652 0.07726622776065932 3.862062417205449e-07 6.413180711595244 0.8148065733751886 TVAISDAAQLPHDYCTTPGGTLFSTTPGGT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 TVAISDAAQLPHDYCTTPGGTLFSTTPGGTR 31 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 1 TVAISDAAQLPHDY(0.007)CT(0.007)T(0.007)PGGT(0.101)LFS(0.079)T(0.079)T(0.27)PGGT(0.449)R 87.111 1.2878000000000001e-08 31442000.0 23835.0 27255.0 34245.0 46658.0 34186.0 34958.0 23753.0 40973.0 26514.0 29229.0 True False 31414.03420120169 36064.64574942591 33790.888924714476 35901.71895891409 29439.863993313655 32772.070733735265 25866.970984341766 34641.56431587373 27915.475910596208 28205.701606615206 1.113747661353477 1.2786296278823113 1.1980162520328639 1.2728532500143128 1.0437557768961505 1.1618952504996043 0.9170830545223904 1.2281759482185366 0.9897103890530087 1.0 14.78369920345536 -6.268749126514172 24.588807747006843 1.0664507697805063 1.2190275906619643 0.4103324427814805 0.09293557037460555 448.9450093900123 1510175.312708423 0.02672304199978049 0.030944384134688564 5.385808079438373e-07 6.268749126514172 0.15257682088145796 TVALWDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVALWDLR 8 0 Q09028-3;Q09028;Q09028-4;Q09028-2;H0YF10;H0YEU5;H0YCT5;H0YDK2;Q5JP02;E9PC52;Q16576;Q16576-2 Q09028-3;E9PC52 RBBP4;RBBP7 Histone-binding protein RBBP4;Histone-binding protein RBBP7 0 98.523 0.02525 3927600.0 27536.0 28384.0 35946.0 29712.0 35229.0 31940.0 29789.0 27616.0 25283.0 28287.0 False True 32197.300939209505 31201.775936679 36803.08896596416 28047.332967603703 28326.13034349252 30265.01017284349 26967.170266316505 26891.10926157067 25652.716044263256 33415.20918023122 0.9635522784115251 0.9337597070958422 1.1013873582972284 0.8393582938932129 0.8477017214140484 0.9057255936841053 0.8070328131379935 0.804756574065672 0.7676958089922616 1.0 15.028217285079862 -5.791333370629024 24.872836708779786 0.8450844735844991 0.9929857867475289 0.45636344426525255 0.07273517509134657 158.74350743871668 132079.4668700129 0.019999900062242254 0.0296693709211509 1.6168384529533727e-06 5.791333370629024 0.1479013131630298 TVANLLSGKS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 TVANLLSGKSPR 12 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 1 TVANLLS(0.001)GKS(0.999)PR 98.421 0.0017285999999999998 701930000.0 1211700.0 926180.0 1498300.0 1673100.0 1758400.0 1317400.0 1323600.0 1332200.0 1416900.0 1508300.0 True False 1596995.3950743042 1225549.5725629544 1478431.5630281728 1287392.6441373208 1514276.512193375 1235022.7697414837 1441397.835847044 1126339.100910525 1491794.4413413205 1455494.8760907887 1.0972181498594908 0.8420157244761808 1.015758686144597 0.8845051022062256 1.0403860137663032 0.8485242992119247 0.9903146067531291 0.7738530168760744 1.0249396723044648 1.0 20.47307832994499 -6.765723074968393 24.999936919592066 0.9173164195156553 0.9656628028725145 0.0476061384129981 0.09815158221767514 355.55544610060826 2075034.0094039203 0.03131801175364254 0.028581220845505254 1.715050549670858e-07 6.765723074968393 0.048346383356859146 TVANLLSGKS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TVANLLSGKSPR 12 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 1 TVANLLS(0.005)GKS(0.995)PR;TVANLLS(0.005)GKS(0.995)PR;TVANLLS(0.001)GKS(0.999)PR 123.63 0.0016712 846560000.0 757410.0 563782.0 758152.0 1006194.0 1063258.0 1015227.0 1007946.0 1138958.0 1040080.0 782084.0 True False 885624.5534706087 619750.5510545634 776229.2189874696 949820.2123049616 854920.2275614174 961986.7089150094 912466.0579829018 1109061.5593257535 1055289.2023619544 923869.6382264607 0.9586033752237269 0.6708203467366778 0.8401934503200967 1.0280889997947307 0.9253688964198407 1.0412580618643572 0.9876567214986628 1.2004524376997636 1.1422490346016543 1.0 19.817329770285433 -6.294301781661479 0.7622087935232045 1.106758827309351 0.7962088625237191 0.5221274399631259 0.09776838576419956 0.537378796488689 0.6771325841618848 0.05715583466075914 0.09603309796271627 5.078064564216165e-07 6.294301781661479 -0.3105499647856318 TVANLLSGKS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 TVANLLSGKSPR 12 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 1 TVANLLS(0.056)GKS(0.944)PR;TVANLLS(0.016)GKS(0.984)PR 98.421 0.0017285999999999998 1050150000.0 960000.0 667440.0 815960.0 702370.0 789720.0 670630.0 572870.0 644680.0 794490.0 525570.0 True False 946310.2239575619 665894.583687391 748874.918496686 754024.6328376343 743270.2222492583 641948.7182148845 602530.4055255619 674634.186320048 705006.169849403 616414.0742219951 1.5351859464791489 1.0802715439744746 1.2148893898016133 1.2232436999257745 1.205796968843345 1.0414244986620689 0.9774767169066404 1.0944496800653605 1.1437217275404103 1.0 19.233540276877555 -2.969126549631718 1.717780201452174 1.1112036830295742 199.99999969299546 0.6743512450414281 0.08711999316638012 414.55445340668314 3.3783759427919735 0.025825084652406547 323108.53031004075 0.0010736765067662045 2.969126549631718 198.8887960099659 TVAS(ph)DLQK ddPTM_PC-9_AZD4547_30min_R2 2 TVASDLQK 8 0 Q7L8J4;Q7L8J4-2 Q7L8J4 SH3BP5L SH3 domain-binding protein 5-like 1 T(0.01)VAS(0.99)DLQK;T(0.12)VAS(0.88)DLQK 123.51 0.0032817 42282000.0 97958.0 133687.0 124842.0 130190.0 142040.0 158347.0 118826.0 148912.0 105967.0 128282.0 True False 129106.606347024 176898.70835822806 123186.51350968637 100176.70691544903 122320.19778886894 148445.53705803485 129401.28380353597 125901.07205734025 111568.19928408191 123790.88622600172 1.0429411266296091 1.4290123752347068 0.995117793120796 0.8092413744624066 0.9881195742112405 1.1991636992324444 1.0453215721171225 1.0170463747023026 0.901263434534226 1.0 16.917545578322212 -5.301573650556394 23.75191292535483 0.9973111248586897 1.2359767427647832 0.3645162549102594 0.127536809092658 268.9888090559937 159190.0705495 0.03388113466163423 0.07053141910576077 4.99374485769183e-06 5.301573650556394 0.23866561790609353 TVAS(ph)DLQK ddPTM_PC-9_Lapatinib_30min_R1 2 TVASDLQK 8 0 Q7L8J4;Q7L8J4-2 Q7L8J4 SH3BP5L SH3 domain-binding protein 5-like 1 T(0.068)VAS(0.932)DLQK;TVAS(1)DLQK 96.171 0.006201600000000001 47349000.0 399670.0 355260.0 295470.0 335840.0 370120.0 335210.0 334550.0 325290.0 333770.0 325080.0 True False 393970.6325094979 354437.41729710886 271177.59714718355 360538.79392939724 348350.26928391703 320873.84971267567 351871.3620342782 340404.1609295292 296177.3078460838 381269.6448581274 1.0333123494688297 0.9296240130236358 0.7112488518410384 0.9456267992789087 0.9136585458135282 0.8415929619366227 0.9228937230636641 0.8928173682858899 0.7768184848712334 1.0 18.540452148548525 -4.88073643415717 4.341943356580031 0.873062599249147 1.0308418881354964 0.26567905238731226 0.07928336526599346 0.2658083506941901 8.066647895192952 0.019089993780605965 0.09726254026768026 1.3160232617477424e-05 4.88073643415717 0.1577792888863494 TVAT(ph)PLNQVANPNSAIFGGAR ddPTM_PC-9_AZD4547_30min_R2 2 TVATPLNQVANPNSAIFGGAR 21 0 Q15056;Q15056-2 Q15056;Q15056-2 EIF4H Eukaryotic translation initiation factor 4H 1 T(0.002)VAT(0.998)PLNQVANPNSAIFGGAR;TVAT(1)PLNQVANPNSAIFGGAR 181.49 8.738399999999999e-13 31105000.0 66623.0 86887.0 92462.0 98826.0 93994.0 114108.0 93335.0 145546.0 116083.0 115162.0 True False 87807.72815551319 114971.52358210848 91235.89346640247 76043.1925464796 80944.55555454052 106972.80872146762 101641.63418614659 123055.21001435468 122218.91039185844 111130.21343258454 0.7901337129059004 1.0345658487541214 0.820981897256495 0.6842710924208748 0.7283757769766573 0.962589789196806 0.9146174658236029 1.1073065210029878 1.099781118174498 1.0 16.761891575983718 -7.383530918927225 1.7115501616811555 1.0742481440017018 0.8241335039178338 0.5246767107409775 0.09928891687759346 0.3218723536826513 1.83385842610318 0.06310780506679231 0.03496051378158464 4.134938752396345e-08 7.383530918927225 -0.25011464008386797 TVAT(ph)PLNQVANPNSAIFGGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVATPLNQVANPNSAIFGGAR 21 0 Q15056;Q15056-2 Q15056;Q15056-2 EIF4H Eukaryotic translation initiation factor 4H 1 T(0.328)VAT(0.672)PLNQVANPNSAIFGGAR;T(0.001)VAT(0.999)PLNQVANPNSAIFGGAR 272.51 2.4531999999999996e-100 15126500.0 42598.0 58796.0 48917.0 39618.0 52300.0 22208.0 44703.0 30187.0 28649.0 24508.0 True False 49809.00005114927 64632.87831077296 50083.36679875556 37398.33190328902 42052.19043869136 21043.373385050352 40468.40821830703 29394.623235770327 29067.9374264169 28951.106394778762 1.7204523852025275 2.2324838791801507 1.729929285458601 1.291775567859945 1.4525244688498444 0.7268590394474684 1.397819056255666 1.0153195126619254 1.004035459993999 1.0 14.821330862816128 -5.838481841926296 1.427104281373672 1.0765585192022897 2.004979684136692 0.7212282799235633 0.22515762237896483 0.21086066261792333 0.8700486748370866 0.07330670948706408 0.15690559472934099 1.4505014192410354e-06 5.838481841926296 0.9284211649344021 TVAT(ph)PLNQVANPNSAIFGGAR ddPTM_PC-9_Lapatinib_30min_R1 2 TVATPLNQVANPNSAIFGGAR 21 0 Q15056;Q15056-2 Q15056;Q15056-2 EIF4H Eukaryotic translation initiation factor 4H 1 T(0.001)VAT(0.999)PLNQVANPNSAIFGGAR;T(0.118)VAT(0.882)PLNQVANPNSAIFGGAR 259.16 5.3213999999999983e-73 21588800.0 33815.0 62161.0 75879.0 61262.0 64057.0 48833.0 53424.0 52050.0 49700.0 43839.0 True False 33332.791899088465 62017.07002366044 69640.52152141045 65767.4118440411 60289.29320090756 46744.52642528293 56190.03331436042 54468.43301786702 44102.262635798215 51416.51273820434 0.6482896276689918 1.2061702888998052 1.3544388332206942 1.279110704743955 1.1725667492830647 0.909134516051106 1.0928402243158972 1.059356811987659 0.8577451150830115 1.0 15.649944144020754 -6.745289576279537 24.551104002125573 0.9943391892356583 1.1567471841473786 0.12641633675284358 0.18845593876976285 404.5434836553263 614989.5845121178 0.06430472219338029 0.06410228439137552 1.7976718745180593e-07 6.745289576279537 0.1624079949117203 TVAT(ph)PLNQVANPNSAIFGGARPR ddPTM_PC-9_AZD4547_30min_R2 2 TVATPLNQVANPNSAIFGGARPR 23 1 Q15056;Q15056-2 Q15056;Q15056-2 EIF4H Eukaryotic translation initiation factor 4H 1 T(0.207)VAT(0.793)PLNQVANPNSAIFGGARPR;T(0.211)VAT(0.789)PLNQVANPNSAIFGGARPR 103.45 2.2681e-06 80730000.0 53741.0 56385.0 63428.0 109000.0 105581.0 81437.0 63311.0 103016.0 82359.0 93768.0 True False 70829.52011775866 74610.34858122854 62586.90327688103 83871.73403321269 90922.90061071917 76344.73151619648 68945.55635034152 87097.24427218051 86712.32860076903 90485.21086075813 0.7827745489453922 0.8245584871989922 0.6916810236889649 0.9269109640721013 1.0048371412941124 0.8437260718072312 0.7619538673169187 0.9625577864454431 0.9583038794505884 1.0 16.465394393166598 -1.5228787456729143 0.11240840398986855 1.0577134680115006 0.16818711218101642 0.3698451978581935 0.08256949340918916 128.88087076478982 1.0115384483183765 0.7739801562326535 17.812535739311837 0.029999999972881764 1.5228787456729143 -0.8895263558304841 TVAT(ph)PLNQVANPNSAIFGGARPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVATPLNQVANPNSAIFGGARPR 23 1 Q15056;Q15056-2 Q15056;Q15056-2 EIF4H Eukaryotic translation initiation factor 4H 1 T(0.047)VAT(0.953)PLNQVANPNSAIFGGARPR 108.47 1.1092000000000001e-06 28263000.0 22007.0 11821.0 23691.0 26012.0 29528.0 23191.0 23673.0 24251.0 21210.0 19979.0 True False 25732.350441937226 12994.51075773261 24255.883288617828 24554.63197204184 23742.200368521597 21974.82313457775 21430.522062322027 23614.436946058435 21520.15612462223 23601.03454632301 1.0903060368574506 0.5505907265305506 1.027746611743206 1.0404048993635069 1.0059813404332556 0.9310957573256625 0.9080331635572668 1.000567873400173 0.9118310505576978 1.0 14.526562480752533 TVAT(ph)PLNQVANPNSAIFGGARPR ddPTM_PC-9_Lapatinib_30min_R1 2 TVATPLNQVANPNSAIFGGARPR 23 1 Q15056;Q15056-2 Q15056;Q15056-2 EIF4H Eukaryotic translation initiation factor 4H 1 T(0.059)VAT(0.941)PLNQVANPNSAIFGGARPR;T(0.01)VAT(0.99)PLNQVANPNSAIFGGARPR 104.55 1.9191999999999998e-06 70712000.0 173438.0 101782.0 162884.0 107199.0 83961.0 78563.0 67275.0 57433.0 94547.0 51479.0 True False 170964.74231536585 101546.33003246746 149492.30627042285 115082.7720653809 79022.57905367718 75203.04362929793 70758.1703208969 60101.546849474624 83898.1212359521 60377.07655854421 2.8316167668302237 1.681868944648285 2.4759778841804088 1.906067312712494 1.3088175770990416 1.2455562262339386 1.1719376683017557 0.9954365178843593 1.3895691215622352 1.0 15.881713283194673 -6.180400040264345 2.195838071918256 1.1621164973457094 2.274326415987309 0.7662376112211616 0.2879921630680527 0.14667284240180506 1.3879284397441554 0.08934199128511199 0.12175139805191566 6.600851458042892e-07 6.180400040264345 1.1122099186415995 up TVATPLNQVANPNSAIFGGAR ddPTM_PC-9_Lapatinib_30min_R1 1 TVATPLNQVANPNSAIFGGAR 21 0 Q15056;Q15056-2 Q15056;Q15056-2 EIF4H Eukaryotic translation initiation factor 4H 0 120.32 0.00028394 0.0 7150.1 6864.8 5095.3 5823.0 7283.7 7033.2 4277.9 4629.9 6272.8 4823.2 False True 7048.13826283225 6848.904977372052 4676.3841024267895 6251.242844958561 6855.287086305167 6732.406431189967 4499.388730074541 4845.022056280929 5566.291208487625 5656.883693489978 1.2459401049633294 1.2107204864851417 0.8266714247295625 1.1050682997341064 1.211848688739054 1.1901263656768684 0.7953829305793402 0.856482529746307 0.9839854432385435 1.0 12.465791793888398 -7.255972475744253 24.97704649860291 0.8970029351682062 1.1238834122078791 0.43511781555394546 0.12385330402605627 456.03669673181656 2083533.8428075726 0.051375649097719765 0.03865043480912349 5.5466086455287504e-08 7.255972475744253 0.22688047703967296 TVAYTEQK ddPTM_PC-9_Lapatinib_30min_R1 2 TVAYTEQK 8 0 P30101 P30101 PDIA3 Protein disulfide-isomerase A3 0 ; 93.429 0.033319999999999995 10159300.0 72467.0 55629.0 83120.0 54904.0 61450.0 68228.0 69886.0 54108.0 68465.0 59078.0 False True 71433.60729117983 55500.1944683356 76286.19445247872 58941.8233143749 57835.63181534835 65310.04748723608 73504.35512517576 56622.05521096536 60753.75073158797 69289.55358351312 1.0309433904070768 0.800989349735707 1.1009768501471542 0.850659591035374 0.8346948251822749 0.9425670120463306 1.0608288165196884 0.8171802570891165 0.8768096717258087 1.0 16.08035024086879 -4.44550830322904 19.497870872560558 0.9203810104282647 4.597128580361622 0.10053209448289702 0.09908494849418233 264.29610851299145 68626.0736440651 0.023299131057408523 1284.1723455201948 3.5850209404842544e-05 4.44550830322904 3.6767475699333576 TVCGSPLAAQPSPSAELPQAAPPPPGS(ph)PSLPGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVCGSPLAAQPSPSAELPQAAPPPPGSPSLPGR 33 0 W0Z7M9;A0A499FIJ6;Q969V6;A0A087WU73;B0QY83 W0Z7M9 mkl1;MKL1 MKL/myocardin-like protein 1 1 TVCGSPLAAQPSPSAELPQAAPPPPGS(0.524)PS(0.476)LPGR 80.895 1.5063e-08 4350200.0 10330.0 15946.0 17103.0 18986.0 19150.0 14147.0 19861.0 13038.0 13340.0 12017.0 True False 12078.664973199955 17529.013496557345 17510.800383488695 17922.275973442498 15397.694969425242 13405.106415629834 17979.622298812053 12695.766314902889 13535.072263199456 14195.586973480338 0.850874641236383 1.2348213236482852 1.2335383113218013 1.2625244737624601 1.0846818097899464 0.9443150495060718 1.2665642028329585 0.8943459920763152 0.9534704192567147 1.0 13.79315488385806 -7.779015433456509 24.999923175384197 0.9429310949478176 1.1304554169633714 0.2667171536151638 0.13346293744873144 332.30594283881015 472660.5832890971 0.07327251858756477 0.035322057603518205 1.6633535389798186e-08 7.779015433456509 0.1875243220155538 TVCST(ph)YLQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVCSTYLQSR 10 0 Q9H422-2;Q9H422 Q9H422-2 HIPK3 Homeodomain-interacting protein kinase 3 1 TVCS(0.024)T(0.749)Y(0.226)LQSR 138.08 0.00028974 6202200.0 7963.6 8496.6 8760.6 9357.6 13596.0 12616.0 11609.0 6992.1 10138.0 7343.8 True False 9311.680191730413 9340.086295926825 8969.48592876051 8833.324009748529 10931.961399702632 11954.394750801304 10509.311478118385 6808.564783742334 10286.249070788317 8675.17280651119 1.0733711476895873 1.076645561332978 1.0339259088912238 1.0182303231030323 1.2601433589308562 1.3780007634924436 1.2114238773699788 0.7848333324993982 1.1857111437674104 1.0 13.08267678063698 -7.712635055102843 24.999999447832565 0.9889497043295814 1.1508526952995377 0.220230651131204 0.13801494210557624 175.98365763571857 90147.22931686183 0.06944673288301895 0.04009498385167706 1.9380498554987692e-08 7.712635055102843 0.1619029909699563 TVCST(ph)YLQSR ddPTM_PC-9_Lapatinib_30min_R1 1 TVCSTYLQSR 10 0 Q9H422-2;Q9H422 Q9H422-2 HIPK3 Homeodomain-interacting protein kinase 3 1 TVCS(0.021)T(0.669)Y(0.31)LQSR 176.33 0.004021500000000001 8140700.0 19209.0 15930.0 16521.0 14416.0 15828.0 14546.0 13927.0 11967.0 15987.0 10730.0 True False 18935.076137500826 15893.115063736286 15162.707152904239 15476.200730366234 14897.028159045301 13923.901488382144 14648.071914665648 12523.030507681353 14186.375709426693 12584.66620317371 1.5046148886114765 1.26289524149065 1.2048557274471352 1.2297664856985489 1.1837444012053684 1.106418022026734 1.1639618944340033 0.9951023178130213 1.1272746913103702 1.0 13.619379330381877 -1.5228787452803376 0.304062732960374 1.0433373514334359 4.649693260622476 0.8325792170400776 0.05645193112575146 21.346856585547528 0.3045240792384982 0.05570697255321097 42.06644077375617 0.029999999999999995 1.5228787452803376 3.60635590918904 TVCSTY(ph)LQSR ddPTM_PC-9_AZD4547_30min_R2 2 TVCSTYLQSR 10 0 Q9H422-2;Q9H422 Q9H422-2 HIPK3 Homeodomain-interacting protein kinase 3 1 TVCS(0.001)T(0.001)Y(0.998)LQSR;TVCS(0.012)T(0.022)Y(0.967)LQSR 183.72 0.0021680999999999996 16915600.0 22940.0 21135.3 41191.0 44974.0 43648.0 38004.0 22932.1 37650.0 28807.0 38013.0 True False 30234.442818358173 27966.872401681943 40644.78042627874 34605.939141373434 37588.22861932239 35627.603872214524 24973.01247463579 31832.0576109303 30329.67920934392 36682.1764402567 0.824227070266679 0.7624103887955191 1.1080253237556892 0.9433992881457081 1.0247000659991197 0.9712510905736542 0.6807941866619797 0.8677799601878678 0.8268233281834048 1.0 15.16279161952967 TVCSTY(ph)LQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVCSTYLQSR 10 0 Q9H422-2;Q9H422 Q9H422-2 HIPK3 Homeodomain-interacting protein kinase 3 1 TVCS(0.001)T(0.23)Y(0.77)LQSR 166.07 0.0013880000000000001 6331900.0 11348.0 9016.9 16558.0 11738.0 12585.0 13331.0 14148.0 13853.0 13527.0 12464.0 True False 13268.992266783458 9912.038241383916 16952.805516564677 11080.357915109456 10119.059592178412 12631.898892115742 12807.79901735023 13489.373428466779 13724.806784430213 14723.624535030285 0.9012041997684753 0.6732063981801019 1.151401645446116 0.7525564027218428 0.6872668864995339 0.857934054353401 0.8698808494388087 0.9161720605122068 0.9321622370752735 1.0 13.845845244900467 -8.08123800148199 1.2273168349834995 0.9882509141634097 0.8351894565670411 0.14802236643215538 0.12687490073282665 0.9094551884885943 2.5199908075628112 0.11722568342208359 0.039454543314274206 8.293961183945206e-09 8.08123800148199 -0.15306145759636858 TVCSTY(ph)LQSR ddPTM_PC-9_Lapatinib_30min_R1 1 TVCSTYLQSR 10 0 Q9H422-2;Q9H422 Q9H422-2 HIPK3 Homeodomain-interacting protein kinase 3 1 TVCST(0.023)Y(0.977)LQSR 159.34 0.00068772 10728000.0 15961.0 13635.0 13924.0 12128.0 16275.0 9752.9 13113.0 14995.0 12922.0 11104.0 True False 15733.393213111087 13603.428995231901 12779.222468194337 13019.933577821994 15317.736497881104 9335.791202120328 13791.926977598228 15691.722441938819 11466.588285307535 13023.311604850036 1.2080946605970624 1.0445445373637396 0.9812575215842338 0.999740616892958 1.1761782995483727 0.7168523249219936 1.0590184275758212 1.2048949543751248 0.8804664000389303 1.0 13.668808727316254 -4.772982244631987 3.3324706230988967 1.0076397066136387 1.237128418697701 0.1802037829286317 0.1309763899256728 0.5912688510035204 10.23131519452062 0.03275368576755193 0.35627204775928695 1.6866219785599802e-05 4.772982244631987 0.2294887120840623 TVDGPS(ph)GK ddPTM_PC-9_AZD4547_30min_R2 1 TVDGPSGK 8 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 TVDGPS(1)GK 67.704 0.045598 4698500.0 43005.0 32176.0 32508.0 32756.0 34755.0 28782.0 23538.0 32854.0 48214.0 53857.0 True False 56679.69544043125 42576.26276402599 32076.922679650113 25204.610275155184 29929.868164968604 26982.256990055746 25632.836400851982 27777.169209814176 50762.49360916815 51971.48282279498 1.090592231776216 0.8192235520621284 0.6172023759456984 0.4849700048215731 0.5758902101565823 0.5191742764403324 0.4932096412998492 0.5344694378747061 0.9767374500791316 1.0 15.66543260135254 -10.648294931329167 11.944738226111053 0.999999839049066 0.6581925600081224 0.17635577893985865 0.20363793524916196 0.0 0.0 0.2069848348069679 0.0502011962829501 2.2475277812680867e-11 10.648294931329167 -0.34180727904094355 TVDGPS(ph)GK ddPTM_PC-9_Lapatinib_30min_R1 2 TVDGPSGK 8 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 TVDGPS(1)GK;TVDGPS(1)GK 76.143 0.025374 9656000.0 97356.0 124635.0 81643.0 108016.0 125592.0 72201.0 184859.0 163504.0 108910.0 88018.0 True False 95967.68558709616 124346.41531505188 74930.62769109382 115959.85697081276 118204.92548337221 69113.13153875158 194430.09449796646 171100.9927406981 96643.40892685692 103231.79402338692 0.9296330311314256 1.2045360297320948 0.7258483532129497 1.123295958070266 1.1450437978109067 0.669494628012511 1.8834322927093448 1.6574447277544704 0.9361787213052075 1.0 16.655527844574053 -7.249408292175977 24.99892778003318 1.4240510229780028 0.9814672668378288 0.2847294851130493 0.30746214754874385 896.433691416028 1862667.482592603 0.11615432850138441 0.08926826119454061 5.631080135827058e-08 7.249408292175977 -0.442583756140174 TVDLKPDWGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVDLKPDWGK 10 1 P31948-2;P31948;P31948-3;F5H783;F5GXD8 P31948-2 STIP1 Stress-induced-phosphoprotein 1 0 79.986 0.023688999999999998 4037200.0 32992.0 31470.0 34545.0 39330.0 38262.0 40675.0 40874.0 35086.0 38701.0 30528.0 False True 38576.8939782975 34594.133622015506 35368.68381264207 37126.4676095804 30764.83576606519 38541.93139575484 37002.11881786639 34165.02967668988 39266.928909901246 36062.48474048495 1.0697236825445307 0.9592831406644307 0.980761144640042 1.0295038702061754 0.8530980598662842 1.0687541824450708 1.0260557220098196 0.9473842393986535 1.0888581081552287 1.0 15.138211182844309 TVDLKPDWGK ddPTM_PC-9_Lapatinib_30min_R1 1 TVDLKPDWGK 10 1 P31948-2;P31948;P31948-3;F5H783;F5GXD8 P31948-2 STIP1 Stress-induced-phosphoprotein 1 0 84.81700000000001 0.015946000000000002 6683400.0 45847.0 45176.0 55250.0 52372.0 49534.0 41829.0 45332.0 44248.0 39348.0 40073.0 False True 45193.213372689934 45071.39774760519 50707.558271167545 56223.61158787048 46620.507507590955 40040.07117816146 47679.0691488205 46303.923615265725 34916.213887190934 46999.56465608388 0.9615666379760792 0.9589747921584397 1.078894211940401 1.1962581355653596 0.9919348795831058 0.8519242991111079 1.014457676314852 0.9851989896947246 0.7429050490720064 1.0 15.520359773118072 -6.525452345998468 24.808511109263772 0.9237207516556615 1.0508214584351137 0.28593259667699966 0.09696518731060005 103.0142580681826 992997.9751859702 0.032932310909649244 0.033122408010420504 2.982274767209865e-07 6.525452345998468 0.12710070677945218 TVDNFVALATGEK ddPTM_PC-9_Lapatinib_30min_R1 2 TVDNFVALATGEK 13 0 P23284 P23284 PPIB Peptidyl-prolyl cis-trans isomerase B 0 ; 186.16 0.00019233 15285800.0 111996.0 82596.0 94955.0 81396.0 84536.0 68393.0 84834.0 82237.0 82573.0 76753.0 False True 110398.91650244883 82404.75403668302 87148.16643689985 87382.13336909632 79563.75868417058 65467.990821869906 89226.28942404999 86058.0312409285 73272.75920776196 90019.65378305606 1.226386815133793 0.9154084755233046 0.9681015508782517 0.9707006158864367 0.8838487523615255 0.7272633038519041 0.9911867650489076 0.9559915821085591 0.8139640192834614 1.0 16.457952395656733 -2.5004712332846317 1.3811418573246037 0.9049960274366771 199.99765379658967 0.5515278093834115 0.08333308565833053 670.9169056880148 2.7262403789287166 0.023890057503115094 421700.2153284402 0.0031588482766858952 2.5004712332846317 199.092657769153 TVDSQGPT(ph)PVCTPTFLER ddPTM_PC-9_AZD4547_30min_R2 1 TVDSQGPTPVCTPTFLER 18 0 H7BZL0;Q9BYG3;C9J808 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 T(0.003)VDS(0.005)QGPT(0.622)PVCT(0.347)PT(0.023)FLER 105.01 0.0025605999999999997 0.0 4123.4 5668.4 6165.7 5861.7 5804.6 7981.4 7345.9 6121.3 5805.1 8386.2 True False 5434.555427951962 7500.599448396473 6083.938789403188 4510.3756273622275 4998.731484689305 7482.321796276525 7999.670869106063 5175.393738480417 6111.9457346534655 8092.601690560622 0.6715461400121718 0.9268464871001038 0.7517902180332957 0.5573455607759892 0.6176915256461872 0.9245879239310715 0.9885165704419933 0.63952161942149 0.755251026599093 1.0 12.982387873925173 -6.765689559279487 24.99652311278249 0.8469793430897935 0.7117578940650824 0.24670387646768555 0.13531384530835233 204.70170125632637 1203900.576470511 0.05072651396185518 0.046309284189123424 1.7151829099036485e-07 6.765689559279487 -0.13522144902471112 TVDSQGPTPVCT(ph)PTFLER ddPTM_PC-9_AZD4547_30min_R2 2 TVDSQGPTPVCTPTFLER 18 0 H7BZL0;Q9BYG3;C9J808 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 TVDSQGPT(0.001)PVCT(0.875)PT(0.124)FLER;TVDSQGPT(0.001)PVCT(0.945)PT(0.054)FLER 128.59 0.00010378 19943100.0 28763.0 29605.0 37100.0 51048.0 40957.0 44462.0 38729.0 43284.0 37341.0 45443.0 True False 37909.03569243398 39174.23729267123 36608.02975929063 39279.67228373798 35270.82751928123 41681.784111314635 42175.80597198556 36595.45236737069 39314.76902683762 43852.054401772715 0.8644757060891886 0.8933272985059421 0.8348076335007637 0.8957316326358954 0.8043141421865838 0.9505092675801673 0.9617749167592159 0.8345208193003456 0.8965319769659029 1.0 15.420356811861918 -6.778391469923705 24.99994006761436 0.9203941639869284 0.861213083941066 0.34067593368121285 0.04802942711697589 344.60106005417197 508193.9011992883 0.016977088796490413 0.015008674825157655 1.6657450450232592e-07 6.778391469923705 -0.05918108004586242 TVDSQGPTPVCT(ph)PTFLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVDSQGPTPVCTPTFLER 18 0 H7BZL0;Q9BYG3;C9J808 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 TVDSQGPTPVCT(0.996)PT(0.004)FLER 142.4 0.00045157 5205700.0 8822.8 8776.6 14196.0 10838.0 14486.0 13683.0 14788.0 15622.0 14408.0 10227.0 True False 10316.325781756881 9647.882845471286 14534.48647862981 10230.781997270089 11647.572288621093 12965.439392455159 13387.173584151495 15211.939052877204 14618.689742741977 12081.074143112552 0.8539245483927638 0.7985947881109202 1.2030789900346694 0.8468437388990516 0.9641172755537968 1.0732025347139174 1.1081112015013626 1.259154514960871 1.2100488391651933 1.0 13.560461111699901 -6.9764707412483355 1.7632803305431584 1.1713602376161687 0.9318093326181937 0.40622503700510604 0.12089866273978453 0.35180841844519173 2.2141011910758364 0.0562156638575528 0.04358337310008466 1.0556726222928284e-07 6.9764707412483355 -0.23955090499797504 TVDSQGPTPVCT(ph)PTFLER ddPTM_PC-9_Lapatinib_30min_R1 2 TVDSQGPTPVCTPTFLER 18 0 H7BZL0;Q9BYG3;C9J808 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 TVDSQGPT(0.002)PVCT(0.997)PT(0.001)FLER;TVDSQGPT(0.026)PVCT(0.972)PT(0.002)FLER 184.83 3.5677999999999993e-10 17496600.0 31544.0 48584.0 50721.0 40779.5 68175.0 62644.0 71537.0 67371.0 74911.0 64506.0 True False 31094.176775538857 48471.50673299208 46550.91516872195 43778.56046642415 64165.080537207075 59964.862150296394 75240.83582677078 70501.30260992746 66473.73433219883 75655.77615115781 0.41099541049468175 0.6406848121701582 0.6152988910683398 0.5786545680128373 0.8481187267051138 0.792601242111224 0.9945154177843871 0.9318693984325548 0.878633961792771 1.0 16.207162612771516 -6.283398756808558 0.7373181334758196 0.9622115146073232 0.4931652282127279 0.849737927890561 0.0729404157808117 0.2762373993068944 0.32471251337185864 0.043034975304270785 0.07447471919956435 5.207163846106704e-07 6.283398756808558 -0.46904628639459534 TVDVPASLPT(ph)PPHNNQEELR ddPTM_PC-9_AZD4547_30min_R2 2 TVDVPASLPTPPHNNQEELR 20 0 Q8NEZ4;Q8NEZ4-3;H0Y765;H7BY37;Q8NEZ4-2;H7C2V8 Q8NEZ4 KMT2C Histone-lysine N-methyltransferase 2C 1 TVDVPASLPT(1)PPHNNQEELR;TVDVPAS(0.001)LPT(0.999)PPHNNQEELR 105.72 0.00029219 12491900.0 45275.0 39481.0 62906.0 84106.0 72340.0 65403.0 54091.0 65441.0 57599.0 53609.0 True False 59671.50822149811 52242.46115696513 62071.8253379498 64716.66112474671 62296.83967929305 61313.34007089905 58904.99421184826 55328.59713457873 60643.56554931095 51732.16522730965 1.1534701468477728 1.0098641904396086 1.199869076911975 1.2509946343901044 1.2042186791440592 1.185207303840657 1.1386531755054405 1.069520227724211 1.172260339052983 1.0 15.658773955729224 -9.265095274536442 0.6425240881916978 0.9956952009862726 1.161929725756128 0.3300661694846351 0.0658739154540806 3.5649552602285155 2.055307380305638 0.1177964398717006 0.028359128696394464 5.431311675407627e-10 9.265095274536442 0.16623452476985545 TVDVPASLPT(ph)PPHNNQEELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVDVPASLPTPPHNNQEELR 20 0 Q8NEZ4;Q8NEZ4-3;H0Y765;H7BY37;Q8NEZ4-2;H7C2V8 Q8NEZ4 KMT2C Histone-lysine N-methyltransferase 2C 1 TVDVPASLPT(1)PPHNNQEELR 101.33 0.00057734 4403500.0 27493.0 23982.0 25895.0 27949.0 26754.0 22375.0 29662.0 21331.0 25371.0 26871.0 True False 32147.0218884982 26362.774468483516 26512.43500733437 26383.10814188058 21511.745755195956 21201.61561106366 26852.200625716905 20771.083852062704 25742.002877783612 31742.499589281048 1.0127438703457918 0.8305198018301564 0.8352346333899682 0.8311603838151974 0.6776953936690021 0.6679252070691722 0.8459384413061307 0.6543619475725465 0.8109633208115813 1.0 14.954128118405338 -2.9409860430996773 0.8447689195005087 0.7647301006108461 6.3126544167008385 0.2967216043991544 0.09974725563394718 49.55949013277624 1.9804122668973174 0.03285542588339992 475.73388690250164 0.001145549755329918 2.9409860430996773 5.5479243160899925 TVDVPASLPT(ph)PPHNNQEELR ddPTM_PC-9_Lapatinib_30min_R1 2 TVDVPASLPTPPHNNQEELR 20 0 Q8NEZ4;Q8NEZ4-3;H0Y765;H7BY37;Q8NEZ4-2;H7C2V8 Q8NEZ4 KMT2C Histone-lysine N-methyltransferase 2C 1 TVDVPAS(0.001)LPT(0.999)PPHNNQEELR;TVDVPASLPT(1)PPHNNQEELR 157.63 3.0393000000000002e-05 12083500.0 65609.0 56593.0 73941.0 60081.0 70611.0 65320.0 56236.0 64002.0 73728.0 54836.0 True False 64673.40362878288 56461.96238556354 67861.85640051411 64499.55716434063 66457.79980656723 62526.41586835705 59147.624915138746 66975.76657078818 65423.97624974108 64314.329535622914 1.005583111815868 0.8779064135977652 1.055159198432229 1.0028800366894148 1.03332803570248 0.9722003839552497 0.9196647985326133 1.0413817115778394 1.01725349112912 1.0 15.972852592169122 -5.268332873498339 24.999897807901235 1.0033949244233502 0.9417447621767128 0.23118989617735675 0.04621350990738168 732.5437738797032 2656642.350128472 0.012061961268069165 0.026032431644503026 5.3909726248247885e-06 5.268332873498339 -0.06165016224663744 TVEDEDQDSEEEKDNDS(ph)YIK ddPTM_PC-9_Lapatinib_30min_R1 1 TVEDEDQDSEEEKDNDSYIK 20 1 Q9Y5T5-4;Q9Y5T5-3;Q9Y5T5-2;Q9Y5T5 Q9Y5T5-4 USP16 Ubiquitin carboxyl-terminal hydrolase 16 1 TVEDEDQDS(0.201)EEEKDNDS(0.425)Y(0.374)IK 62.765 0.030636 0.0 10489.0 10104.0 9259.8 10985.0 12690.0 11077.0 14602.0 10835.0 7466.6 8441.6 True False 10339.424936552974 10080.604808787915 8498.494987861664 11792.87354488577 11943.599149499916 10603.262531748182 15358.020111865273 11338.43365511218 6625.632881216322 9900.719312275043 1.0443104799197789 1.0181689320582847 0.8583714697703951 1.1911128043257229 1.2063365067517957 1.070958805851825 1.551202455848253 1.1452131201270033 0.6692072234591859 1.0 13.273317629102175 -5.777860714619044 24.99412078549584 1.1448251656807347 0.9780721225408358 0.08226121059791536 0.21072147928780016 537.2092316534695 817658.6976746677 0.061153326503988324 0.09099997427356997 1.6677820118996619e-06 5.777860714619044 -0.16675304313989892 TVEDLKNNESQWKDS(ph)PLATR ddPTM_PC-9_AZD4547_30min_R2 1 TVEDLKNNESQWKDSPLATR 20 2 O95155-2;O95155;O95155-4;O95155-3;K7EP75 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 TVEDLKNNES(0.056)QWKDS(0.941)PLAT(0.003)R 53.504 0.0093525 19764000.0 84580.0 71836.0 103570.0 145910.0 107160.0 96645.0 85034.0 93887.0 71211.0 94857.0 True False 111474.68062671022 95055.58217045525 102196.59412856426 112272.7037870281 92282.6837162431 90601.77287207062 92601.86126731454 79378.92145862967 74975.06807986209 91536.08530222368 1.2178222420005782 1.0384492832155896 1.1164623633525828 1.226540368384103 1.008156328857132 0.9897929605896052 1.0116432329564018 0.8671871994148008 0.8190766278928986 1.0 16.48205297347804 -6.905893255446939 1.0983158826786628 0.8957709883130949 1.1390766426032293 0.6325360759210895 0.07565883985685311 0.32485860263626654 0.8199392583175266 0.044255674586354724 0.03472849171569907 1.2419575288554964e-07 6.905893255446939 0.2433056542901344 TVEDLKNNESQWKDS(ph)PLATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVEDLKNNESQWKDSPLATR 20 2 O95155-2;O95155;O95155-4;O95155-3;K7EP75 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 T(0.003)VEDLKNNES(0.087)QWKDS(0.907)PLAT(0.003)R;TVEDLKNNES(0.004)QWKDS(0.973)PLAT(0.023)R 56.799 0.006439699999999999 26452000.0 54791.0 36283.0 41426.0 61047.0 57168.0 63688.0 53709.0 61148.0 50431.0 43593.0 True False 64066.03412842193 39884.93645400664 42413.75294897986 57626.73450704439 45966.34078392175 60348.089163683675 48621.29470051341 59542.92979166142 51168.45796892146 51496.065818001865 1.2440957015016454 0.7745239528582349 0.823630937145357 1.1190512050126242 0.892618495291983 1.1718970800015434 0.9441749370204607 1.1562617230236365 0.9936381965519805 1.0 15.652174597444079 -5.77070041529 24.999506067801846 1.0415782036257064 0.9301275598943124 0.07602431337291016 0.14351683583942373 418.10499878859923 1128645.7728546048 0.03868189855591784 0.05826888601720386 1.695506990559918e-06 5.77070041529 -0.11145064373139402 TVEDLKNNESQWKDS(ph)PLATR ddPTM_PC-9_Lapatinib_30min_R1 2 TVEDLKNNESQWKDSPLATR 20 2 O95155-2;O95155;O95155-4;O95155-3;K7EP75 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 TVEDLKNNES(0.179)QWKDS(0.82)PLAT(0.001)R;TVEDLKNNES(0.056)QWKDS(0.924)PLAT(0.02)R 63.43600000000001 0.0026261 37600000.0 321080.0 175194.0 203452.0 186938.0 191365.0 184955.0 150557.0 171126.0 191247.0 123556.0 True False 316501.3403211388 174788.34905688767 186724.96190743137 200686.04412688743 180109.2869380656 177044.90580116338 158352.10477894128 179077.13868617726 169706.7489398091 144912.48997197853 2.1840859982624004 1.2061648315523816 1.288536011930635 1.3848774813385218 1.2428831149950774 1.2217366897456405 1.0927429706684464 1.2357605525983653 1.1710981501499629 1.0 17.144822420222447 -4.760988703540073 24.999996356816567 1.2186854458244034 2.184087087556386 0.8964446395548799 0.09974540799189045 3.2071089802017316 177713.2154152103 0.02492476261883853 0.14267929351693065 1.7338490964208842e-05 4.760988703540073 0.9654016417319826 TVEEAADLS(ph)LGY(ph)MKS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 TVEEAADLSLGYMKSR 16 1 Q7L266-2;Q7L266 Q7L266-2 ASRGL1 Isoaspartyl peptidase/L-asparaginase;Isoaspartyl peptidase/L-asparaginase alpha chain;Isoaspartyl peptidase/L-asparaginase beta chain 3 T(0.003)VEEAADLS(0.997)LGY(1)MKS(1)R 47.916000000000004 0.045574 0.0 5487.1 8113.3 9012.8 4871.0 6891.7 8377.9 6105.8 9568.6 6538.7 5871.5 True False 7231.8836612298655 10735.765560771133 8893.284383141097 3748.0662061998078 5934.906414401211 7854.028588596626 6649.204371498088 8089.9927345537235 6884.322332979377 5665.940572145511 1.2763783116227394 1.8947896512627629 1.5696042466208737 0.6615082100623824 1.0474706430169722 1.3861826626294027 1.1735393774135978 1.4278287305597879 1.215036099535457 1.0 12.468099754588373 -5.558780199816192 24.999368700921682 1.153877861778476 1.622237870856216 0.40932107970980647 0.2458604438414687 159.58032397106453 111120.35893281894 0.0680716610490976 0.11790403923296791 2.7619753621030464e-06 5.558780199816192 0.46836000907774 TVEIPDPVEAGEEVK ddPTM_PC-9_Lapatinib_30min_R1 2 TVEIPDPVEAGEEVK 15 0 P21980 P21980 TGM2 Protein-glutamine gamma-glutamyltransferase 2 0 ; 176.05 0.00010521 4495200.0 36594.0 36243.0 34998.0 33538.0 33710.0 26932.0 34613.0 29028.0 32394.0 33856.0 False True 36072.16284948231 36159.081560263265 32120.59953618683 36004.49639948829 31727.24407640994 25780.181141558372 36405.091777290305 30376.746851923977 28745.446596057318 39707.96448971569 0.9084364638944147 0.9106254129351913 0.808920828578509 0.9067323611819339 0.7990146179522059 0.649244590420529 0.9168209009232688 0.7650038787506097 0.7239214340362964 1.0 15.27714078685202 -5.601712597460634 1.11132188443329 0.8000139220105796 0.913879811930778 0.10058405818899652 0.09659725294758631 1.2629025520374955 2.8010624618744435 0.03370251847709336 0.1219091945150492 2.502000559871962e-06 5.601712597460634 0.11386588992019842 TVESLEETLKK ddPTM_PC-9_Lapatinib_30min_R1 2 TVESLEETLKK 11 1 F2Z3J9;Q14914-2;Q14914 F2Z3J9 PTGR1 Prostaglandin reductase 1 0 ; 85.92399999999999 0.0070861000000000006 10845900.0 39406.0 43416.0 43200.0 32696.0 40651.0 35738.0 42344.0 37406.0 30850.0 31674.0 False True 38844.06321382464 43315.47291947107 39648.262756822405 35100.57291065862 38259.98810294099 34209.56904934696 44536.365129216785 39144.01931731668 27375.348135098102 37148.808697047905 1.0456341556091797 1.1659989765139684 1.0672822130087074 0.9448640250325968 1.029911575764242 0.9208793027073701 1.1988638853109694 1.0537086030548086 0.7369105254046419 1.0 15.181028326129777 -4.590435073373603 0.2807178670990701 0.9555192391083208 1.2444628174649763 0.13292546562355323 0.11529804022620477 21.800578384193866 1.3113958627803302 0.1469511938522134 2.2185434406391638 2.567822066454062e-05 4.590435073373603 0.2889435783566555 TVFAEHISDECK ddPTM_PC-9_AZD4547_30min_R2 1 TVFAEHISDECK 12 0 P39023;G5E9G0;B5MCW2;H7C422;H7C3M2;F8WCR1 P39023 RPL3 60S ribosomal protein L3 0 83.204 0.0094657 3046300.0 9576.6 10724.0 33153.0 70668.0 44679.0 41002.0 24359.0 48898.0 27180.0 39137.0 False True 12621.759594345629 14190.323280750079 32713.369558214632 54376.584409716255 38476.092065677796 38438.13845828178 26526.903810364223 41341.937664256824 28616.679310930256 37766.8255423757 0.3342022903191472 0.37573513465747976 0.8661932552819163 1.4397975903138542 1.0187801466794257 1.0177752010200816 0.7023863782408746 1.0946627647555318 0.7577200069098035 1.0 15.204831903948632 -5.306547464010646 4.039736108465762 1.0058276114072415 0.34302449478731944 0.647568089659599 0.18841081524775669 0.12681063293237438 4.456507251692349 0.05162732719361152 0.12369830307049484 4.936879601818631e-06 5.306547464010646 -0.6628031166199221 TVFAEHISDECK ddPTM_PC-9_Lapatinib_30min_R1 2 TVFAEHISDECK 12 0 P39023;G5E9G0;B5MCW2;H7C422;H7C3M2;F8WCR1 P39023 RPL3 60S ribosomal protein L3 0 ; 78.964 0.013345 8944500.0 86935.0 110079.0 162498.0 140351.0 190103.0 220610.0 161611.0 140858.0 198817.0 116468.0 False True 85695.29095807343 109824.11883873353 149138.04170041974 150672.88073721077 178921.51529687832 211175.02456702787 169978.4268113039 147402.77690741033 176424.13582417477 136599.33861614487 0.6273477736146592 0.8039871931396984 1.0917918286523307 1.1030278935728501 1.309827098062767 1.5459447073931059 1.2443576120742206 1.0790885109745953 1.2915445829495615 1.0 17.059590972870687 -5.195464140706846 1.2692888292384241 1.2553943255884081 0.5513986205606215 0.680652735677588 0.14082659179716445 0.4429385547272165 1.0028482882495853 0.04633329484126596 0.33577448543542804 6.375817233939738e-06 5.195464140706846 -0.7039957050277866 TVFPGAVPVLPAS(ph)PPPK ddPTM_PC-9_AZD4547_30min_R2 3 TVFPGAVPVLPASPPPK 17 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;M0R2S2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 TVFPGAVPVLPAS(1)PPPK;TVFPGAVPVLPAS(1)PPPK;TVFPGAVPVLPAS(1)PPPK 173.87 8.8042e-08 43202000.0 59398.0 78393.0 82572.0 68153.0 61400.0 78106.0 74682.0 83848.0 74239.0 63692.0 True False 78285.32844484912 103732.00419133174 81477.04132841372 52441.3788033536 52875.66984114721 73222.01947277112 81328.5533217957 70891.21823535937 78163.12197807756 61462.162466336005 1.2737158164216478 1.687737626350972 1.3256455363580844 0.8532302915973179 0.8602962817995253 1.1913349048347626 1.3232296108413186 1.153412366090891 1.2717274960979283 1.0 15.90741090672399 -5.528543564471773 24.72839149798537 1.1025707934226412 1.4872179641584242 0.45249405187163283 0.1746275840929386 112.18627403152355 489720.2520364338 0.0503372042344519 0.08753216091625564 2.961122917581431e-06 5.528543564471773 0.38464717073578303 TVFPGAVPVLPAS(ph)PPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVFPGAVPVLPASPPPK 17 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;M0R2S2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 TVFPGAVPVLPAS(1)PPPK;TVFPGAVPVLPAS(1)PPPK 125.45 3.8441999999999995e-05 33161000.0 108646.0 173360.0 133558.0 118619.0 141421.0 95588.0 139450.0 101127.0 93367.0 99071.0 True False 127037.62194368639 190570.0351036738 136742.52924153564 111973.16199798662 113710.57024914298 90575.19700694311 126240.28646942934 98472.52340291324 94732.31574198998 117031.78805439526 1.0854967189311036 1.6283613048370984 1.168422114323153 0.9567756236104208 0.9716212333378295 0.7739367099547741 1.0786837368557853 0.8414168922818145 0.809457988439511 1.0 16.83654092082314 -5.6301992306985635 3.236927326463657 0.9128592862091192 1.3661435781865863 0.5816954858922595 0.15058196579986893 0.1488501400831747 3.070495542369851 0.039877963553935664 0.07580317347842284 2.343153657210652e-06 5.6301992306985635 0.4532842919774671 TVFPGAVPVLPAS(ph)PPPK ddPTM_PC-9_Lapatinib_30min_R1 2 TVFPGAVPVLPASPPPK 17 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;M0R2S2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 TVFPGAVPVLPAS(1)PPPK;TVFPGAVPVLPAS(1)PPPK 180.1 2.192e-06 30930000.0 65076.0 117519.0 108221.0 116160.0 160314.0 152277.0 172572.0 175965.0 142831.0 141104.0 True False 64148.00430652315 117246.89197584601 99323.48712514086 124702.79389840037 150884.64570945082 145764.4676850247 181506.93375871913 184140.9762918152 126743.86870289127 165493.63839073872 0.38761613395112215 0.7084676674943858 0.6001649857418275 0.7535201661587189 0.9117247477102695 0.8807859268938636 1.0967607910714503 1.112677067725402 0.7658534185081041 1.0 17.33641623504314 -5.788075056092787 0.7565543805413528 1.00371458577833 0.4486507740279297 0.7236587075446732 0.11296752718424576 0.5065599455484842 0.5138821382256853 0.05575504937643022 0.19140313760776667 1.6290144770760103e-06 5.788075056092787 -0.5550638117504003 down TVFPGAVPVLPAS(ph)PPPKDSLR ddPTM_PC-9_AZD4547_30min_R2 2 TVFPGAVPVLPASPPPKDSLR 21 1 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;M0R2S2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 TVFPGAVPVLPAS(1)PPPKDSLR;TVFPGAVPVLPAS(0.997)PPPKDS(0.003)LR 147.26 1.0901e-05 508630000.0 106058.0 94763.0 138087.0 182524.0 160622.0 132572.0 119650.0 139914.0 116492.0 140933.0 True False 139782.23785655785 125393.28655853418 136255.87615555694 140445.91176768905 138322.40783753636 124282.25188262321 130298.61820723701 118293.50620386965 122649.52929686858 135998.97856666634 1.0278182919442809 0.9220163848294399 1.0018889670466509 1.032698283824557 1.017084167067704 0.9138469508555932 0.9580852707902139 0.8698117254305884 0.9018415475579922 1.0 17.053236290454052 -6.766390393211329 24.99826698261773 0.9224158316884861 0.9978401094921954 0.40086100212486553 0.043365058682045717 125.2541085260675 632419.2052833572 0.015189019925659238 0.01381184343573361 1.712417300264482e-07 6.766390393211329 0.0754242778037093 TVFPGAVPVLPAS(ph)PPPKDSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVFPGAVPVLPASPPPKDSLR 21 1 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;M0R2S2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 TVFPGAVPVLPAS(1)PPPKDSLR;TVFPGAVPVLPAS(1)PPPKDSLR 132.26 9.204e-07 282340000.0 194798.0 219520.0 220822.0 256128.0 295350.0 300090.0 299570.0 302190.0 278660.0 239097.0 True False 227773.45396412455 241312.4948428616 226087.2339520986 241777.97853818035 237478.287687715 284352.7521217473 271192.56090101856 294257.8326967719 282734.87532707374 282443.39340918936 0.8064393052881155 0.8543747188777773 0.8004691886156287 0.8560227790065705 0.8407995840202527 1.006760146482845 0.960166062401498 1.041829405690741 1.0010320011892155 1.0 18.107602229642694 -6.750040086019481 6.888655535812229 1.00229154016333 0.8319500954947535 0.9219099390690763 0.024790852686139172 0.03691433516984543 8.1300997603376 0.008260165709878597 0.00790485438585858 1.7781152798085635e-07 6.750040086019481 -0.1703414446685766 TVFPGAVPVLPAS(ph)PPPKDSLR ddPTM_PC-9_Lapatinib_30min_R1 2 TVFPGAVPVLPASPPPKDSLR 21 1 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;M0R2S2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 TVFPGAVPVLPAS(1)PPPKDSLR;TVFPGAVPVLPAS(1)PPPKDSLR 152.4 1.6945e-05 368290000.0 585768.0 388130.0 455341.0 469805.0 506745.0 540056.0 443592.0 428755.0 560092.0 385778.0 True False 577414.8409033043 387231.30883163685 417904.62064708886 504356.0269235366 476939.2553990026 516959.0638120239 466559.0232476741 448676.5225470819 497008.5409297685 452459.21328312764 1.2761699263751876 0.855836940575958 0.9236293755954171 1.1146994295106427 1.0541044173644807 1.142553955440256 1.0311626099118099 0.9916397088953106 1.0984604276778513 1.0 18.78742822144754 -4.731678289100669 24.933628261372363 1.027939078783122 1.2761714762153265 0.4537426125347742 0.08302416462891196 3779.5409308946623 3166292.749983469 0.021853252125918408 2.686647283046633 1.8549051666325994e-05 4.731678289100669 0.2482323974322045 TVFS(ph)PTLPAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVFSPTLPAAR 11 0 C9J6P4;Q7Z2W4-3;Q7Z2W4-2;Q7Z2W4 C9J6P4 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 T(0.007)VFS(0.974)PT(0.019)LPAAR;TVFS(0.5)PT(0.5)LPAAR 140.78 0.00012456 36951900.0 67937.0 66919.0 83764.0 96675.0 109796.0 109411.0 101761.0 108062.0 98827.0 94437.0 True False 79437.3922830868 73562.27606773605 85761.25143673897 91258.61317457892 88282.2619771809 103673.29455294239 92121.46139416019 105225.4870011535 100272.15791268466 111557.68053711914 0.7120746137838102 0.6594102325680687 0.7687615144365 0.8180397148380473 0.7913597840339313 0.9293245794801789 0.8257742627008828 0.9432383901719908 0.8988368835736111 1.0 16.76743031828657 -4.06599390569446 0.19929980584434298 1.0166147148290106 0.24926427919107863 0.8317836790950751 0.041930658858961745 7.04042329314501 0.20407150667166676 0.08413091930665467 1.400287925905401 8.590255758321551e-05 4.06599390569446 -0.7673504356379319 TVGSTST(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 TVGSTSTPR 9 0 B4DZM6;Q99640-4;Q99640-3;Q99640 B4DZM6 PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 1 TVGS(0.003)T(0.003)S(0.03)T(0.964)PR 96.665 0.012303 22886000.0 68889.0 67269.0 124290.0 102580.0 101670.0 63280.0 92799.0 104290.0 90272.0 78457.0 True False 90794.26901978551 89012.38873300799 122641.83339035668 78931.76584520144 87554.87545194541 59323.09159650915 101057.93122451635 88174.37684578807 95043.59362605952 75710.24431045205 1.199233602357443 1.1756980781624493 1.6198842641090985 1.0425506688571688 1.1564468751801158 0.7835543543255928 1.3347986411208155 1.1646294058202544 1.255359753381993 1.0 16.20820090322075 TVGSTST(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 TVGSTSTPR 9 0 B4DZM6;Q99640-4;Q99640-3;Q99640 B4DZM6 PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 1 TVGS(0.007)T(0.007)S(0.076)T(0.91)PR 101.9 0.008193899999999999 19227000.0 108080.0 120750.0 51207.0 39665.0 46850.0 42621.0 42731.0 39008.0 71563.0 20281.0 True False 106538.75938055558 120470.41079385778 46996.958124736215 42582.09641856113 44094.37511064393 40798.199184403624 44943.4020956112 40820.454085705234 63502.82134820179 23786.543827266167 4.478950794794819 5.064645442763497 1.9757791828026856 1.7901758543731727 1.85375292143532 1.715179787390434 1.8894465047962636 1.7161153962566578 2.6696951776327182 1.0 14.53785804368356 -5.266567364767349 24.445568084416642 1.8498250447530538 4.771798282980235 0.8952973714390284 0.40285533982482874 72.89009550371216 347476.0573932372 0.09744396998394264 0.21341454782286526 5.412932796870289e-06 5.266567364767349 2.9219732382271815 TVHPNS(ph)PGIPYR ddPTM_PC-9_AZD4547_30min_R2 1 TVHPNSPGIPYR 12 0 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;F8VWY3;C9J102;C9JNI4 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 T(0.007)VHPNS(0.993)PGIPYR 74.296 0.011895999999999999 9098900.0 29927.0 46449.0 59148.0 80723.0 63198.0 60471.0 46790.0 67606.0 56603.0 62139.0 True False 39443.16347972996 61462.730890298444 58363.658873383385 62113.559507917635 54424.048576886344 56689.73881056426 50954.219355759386 57159.04613132945 59594.91902268523 59963.53252363957 0.657785854497151 1.025001835341636 0.9733192228188781 1.0358555757773351 0.9076191192610378 0.9454035882261493 0.8497534620007848 0.9532301338116712 0.9938527053787396 1.0 15.871797756234447 -4.75383545332005 24.99989618654059 0.9599152540292236 0.6577853162374965 0.7510170161777019 0.052978497874633254 144.89093390093797 476327.7510104775 0.01386043140674064 0.1435535690906301 1.7626437551941114e-05 4.75383545332005 -0.30212993779172714 TVHPNS(ph)PGIPYR ddPTM_PC-9_Lapatinib_30min_R1 1 TVHPNSPGIPYR 12 0 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;F8VWY3;C9J102;C9JNI4 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 T(0.001)VHPNS(0.999)PGIPYR 80.102 0.0083083 7338100.0 42977.0 39131.0 46812.0 36229.0 41931.0 44359.0 41184.0 30106.0 43585.0 29233.0 True False 42364.14009898347 39040.39457370149 42963.29805954563 38893.40151640111 39464.70101951783 42461.868975879515 43316.306005140344 31504.83466735649 38675.99832960292 34285.88509947599 1.2356145969710126 1.1386725021224013 1.2530899504240087 1.1343852259773084 1.1510480451362473 1.2384650083462037 1.2633859642084133 0.9188864331764908 1.1280443312864634 1.0 15.065327145799966 -7.75487381857574 24.999999721067773 1.0175990289773569 1.1984478743564073 0.6324740171378385 0.06508566749777121 94.04537290068681 358104.67482400726 0.030137028161273238 0.016879102122543364 1.758434441384549e-08 7.75487381857574 0.18084884537905044 TVHTEWTQR ddPTM_PC-9_AZD4547_30min_R2 1 TVHTEWTQR 9 0 H7C393;C9JIF9;P13798 H7C393 APEH Acylamino-acid-releasing enzyme 0 140.11 7.591600000000001e-09 0.0 3893.1 3293.2 6016.2 7993.2 6344.1 5779.3 5421.7 8620.3 4740.4 4829.1 False True 5131.0248184895445 4357.662497964023 5936.4212570847485 6150.491233708947 5463.331222137165 5417.919457391045 5904.220796775388 7288.230709787578 4990.967866281596 4660.034678863641 1.1010700932682234 0.9351137487729272 1.2739006608706949 1.319838082236924 1.1723799496422225 1.1626350082682682 1.2669907422695714 1.563986367493048 1.0710151769726002 1.0 12.186124975773067 -5.270500279470016 24.710500401166268 1.2492167257675846 1.0180919191906128 0.23060335470660687 0.15034238814069525 625.1680445457857 1704935.2182114716 0.038289730413300395 0.08165068511973393 5.364135262562074e-06 5.270500279470016 -0.23112480657697176 TVHTEWTQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVHTEWTQR 9 0 H7C393;C9JIF9;P13798 H7C393 APEH Acylamino-acid-releasing enzyme 0 93.178 0.0050211000000000006 0.0 6022.9 4259.4 9576.4 9600.8 11149.0 10282.0 6905.0 8441.1 8484.3 4625.8 False True 7042.4580123026135 4682.245082606065 9804.737694699246 9062.898302213562 8964.433483766155 9742.79381957348 6250.908412129162 8219.530069084734 8608.366836781348 5464.420922187345 1.2887839558090994 0.8568602509361258 1.7942866836792877 1.658528585419768 1.6405093259502774 1.7829508301629062 1.1439287897366066 1.5041905054771203 1.5753484146560799 1.0 12.415852902800173 -10.891138792662499 3.5901503761932596 0.9974716416309914 1.4740416762166852 0.2011517716543253 0.2819766814940265 158765124.1350569 234962916.19086197 4222013.037486534 0.0767992036471352 1.284875971198467e-11 10.891138792662499 0.4765700345856938 TVIIEQS(ph)WGSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVIIEQSWGSPK 12 0 P10809;E7ESH4;E7EXB4;P10809-2;C9JL19;C9JCQ4;C9JL25 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 1 TVIIEQS(0.968)WGS(0.032)PK 102.87 0.0022721 33794000.0 71851.0 69136.0 65584.0 72873.0 76958.0 59293.0 79750.0 67089.0 55736.0 50847.0 True False 84013.95517806307 75999.36517609372 67147.77128870491 68790.16206745373 61878.63234762545 56183.57070063898 72195.50266000025 65327.98483667128 56551.03355784746 60065.158595369445 1.3987136160586096 1.2652820196158223 1.117915491425698 1.145258976686643 1.0301917749767802 0.9353770474347884 1.2019530847549607 1.087618618919414 0.9414947846688464 1.0 15.874240763208489 -4.596334431588876 0.7822549107606732 1.0407890610176465 1.7157964677018336 0.7104770678276024 0.07514364760456081 1.9463633256949393 0.7484254914440918 0.029890046260534216 1.2270583838341573 2.53317718792307e-05 4.596334431588876 0.6750074066841871 TVIIEQS(ph)WGSPK ddPTM_PC-9_Lapatinib_30min_R1 1 TVIIEQSWGSPK 12 0 P10809;E7ESH4;E7EXB4;P10809-2;C9JL19;C9JCQ4;C9JL25 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 1 TVIIEQS(0.846)WGS(0.154)PK 122.52 0.00039703 27404000.0 199490.0 160360.0 94410.0 108700.0 106440.0 86463.0 85201.0 67241.0 104760.0 75419.0 True False 196645.2360180146 159988.6962724888 86647.97423313893 116694.16061257024 100179.4084690916 82765.17904509732 89612.2908883053 70365.26233533912 92960.82562829422 88455.07366049924 2.223108611867327 1.8087000513565095 0.9795704265162203 1.3192477919407524 1.132545645189237 0.93567475126141 1.0130825421303429 0.7954915351199537 1.0509383100520449 1.0 16.432657275827673 -4.258086697426236 0.7749495730460982 0.9698890327052239 4.361761535355042 0.882894739159155 0.14553247711985579 1.6241391305470243 0.42151391635326435 0.05456088085345709 5.755334483216531 5.519672400544041e-05 4.258086697426236 3.391872502649818 up TVIIEQSWGS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 TVIIEQSWGSPK 12 0 P10809;E7ESH4;E7EXB4;P10809-2;C9JL19;C9JCQ4;C9JL25 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 1 TVIIEQS(0.003)WGS(0.997)PK;T(0.01)VIIEQS(0.062)WGS(0.928)PK 201.76 2.4247e-06 90222000.0 527470.0 542200.0 481050.0 597180.0 559700.0 549720.0 556570.0 596310.0 525130.0 525640.0 True False 695194.4879424301 717455.5467011096 474670.9626875141 459509.37733902683 481995.3161252461 515345.9214986253 606103.6517810422 504163.99134060607 552887.2997258573 507237.503592364 1.3705502511523984 1.414437106128661 0.9357962676769624 0.9059057622606443 0.9502359599036992 1.0159854463615876 1.1949109588476543 0.9939406841371337 1.0899968866856093 1.0 18.952301892324314 -5.256506215195065 24.99805919231726 1.0114748082164573 1.392493724069666 0.7902387714303626 0.07865068938200868 185.99896161896226 942513.5917764468 0.022214555661126612 0.05500954511003347 5.539796158709915e-06 5.256506215195065 0.3810189158532087 TVIIEQSWGS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TVIIEQSWGSPK 12 0 P10809;E7ESH4;E7EXB4;P10809-2;C9JL19;C9JCQ4;C9JL25 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 1 TVIIEQS(0.007)WGS(0.993)PK;TVIIEQS(0.001)WGS(0.999)PK;TVIIEQS(0.012)WGS(0.988)PK 152.88 0.00020622 44295300.0 261784.0 244665.0 203524.0 273298.0 290134.0 231241.0 278560.0 251281.0 224585.0 232379.0 True False 306098.8607303169 268953.72426534607 208376.78402906796 257985.99910407106 233284.32544434632 219114.31488348474 252172.7802002465 244685.140004227 227869.13075192264 274507.4731888484 1.1150838888809962 0.979768314286724 0.7590933012075572 0.9398141191099327 0.8498286867543949 0.7982089242894465 0.9186372133000668 0.8913605781358636 0.8301017385969643 1.0 18.06648590011804 -4.9520616094039 3.8895831447629314 0.8694698666274403 1.1060662634767817 0.5582136632337902 0.06698989371592795 0.1494192255468924 4.595551444282587 0.015970979152724277 0.07678010217264367 1.1167048197982616e-05 4.9520616094039 0.23659639684934142 TVIIEQSWGS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 TVIIEQSWGSPK 12 0 P10809;E7ESH4;E7EXB4;P10809-2;C9JL19;C9JCQ4;C9JL25 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 1 T(0.001)VIIEQS(0.09)WGS(0.909)PK;T(0.048)VIIEQS(0.146)WGS(0.807)PK;TVIIEQS(0.034)WGS(0.966)PK 158.91 0.00049829 28770200.0 288155.0 235907.0 148449.0 177704.0 154202.0 122911.0 109031.8 109732.6 148266.0 110443.0 True False 284045.8568588446 235360.77183558294 136244.09624971126 190772.94496316597 145132.1415327966 117654.38304953506 114676.93310730523 114831.17719455106 131566.7217698039 129532.92539395302 2.192846768456483 1.8169957261427703 1.0518105403344156 1.4727757007182656 1.1204266489882873 0.9082971197609307 0.8853110725210155 0.8865018438000298 1.0157009993379322 1.0 16.98295933115167 -2.1845113195070875 0.48208390404216944 0.9167126472969318 19.834711405180677 0.8720627640296037 0.15230740161784248 16.387017271186494 0.3510708037567608 0.08867034232838368 289.99940592114996 0.006538658873382764 2.1845113195070875 18.917998757883744 up TVIIEQSWGSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVIIEQSWGSPK 12 0 P10809;E7ESH4;E7EXB4;P10809-2;C9JL19;C9JCQ4;C9JL25 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 151.26 0.00085367 1923600.0 16164.0 15773.0 13855.0 17285.0 20043.0 15744.0 17890.0 17561.0 17424.0 14614.0 False True 18900.24594644765 17338.839199874517 14185.355745380108 16316.577488726098 16115.718029879366 14918.356924272011 16195.329687616311 17100.042357417526 17678.79303703054 17263.402515639642 1.0948158064046252 1.0043697460084438 0.8217010367758614 0.9451542054901532 0.9335192187796966 0.8641608692583542 0.9381308043385006 0.9905371980944011 1.0240619148522188 1.0 14.075429218843892 -7.8560761476778795 3.865861149069429 1.0104767356152742 0.9373982726997828 0.1424842150087533 0.0695842117372245 0.44766669380477664 12.487504982454514 0.04404598932095849 0.019842610224703846 1.3929125531100281e-08 7.8560761476778795 -0.07307846291549136 TVIIEQSWGSPK ddPTM_PC-9_Lapatinib_30min_R1 2 TVIIEQSWGSPK 12 0 P10809;E7ESH4;E7EXB4;P10809-2;C9JL19;C9JCQ4;C9JL25 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 ; 265.0 3.0355e-50 19927000.0 179459.0 182158.0 208976.0 157343.0 166328.0 134749.0 204725.0 171495.0 177043.0 139985.0 False True 176899.8817512502 181736.22434275385 191794.79995068815 168914.52910086117 156544.91405342973 128986.09938526087 215324.6587728816 179463.28377327797 157102.5529945598 164181.22073171253 1.0774672094826312 1.1069245528374274 1.1681896327479426 1.0288297793624237 0.9534885497607474 0.7856324786135938 1.3115060164203691 1.0930804569088797 0.9568850340763398 1.0 17.324929593595016 -5.841988815823213 8.486418557731447 1.021796834618303 1.1162536825330307 0.11474170172748588 0.12587990955104034 0.6643404178776181 62.28371096891145 0.037573410057114225 0.05593703158645141 1.4388356314203088e-06 5.841988815823213 0.09445684791472764 TVIRLPS(ph)GSGAASPTGSAVDIR ddPTM_PC-9_AZD4547_30min_R2 2 TVIRLPSGSGAASPTGSAVDIR 22 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 TVIRLPS(0.702)GS(0.292)GAAS(0.006)PTGSAVDIR;T(0.001)VIRLPS(0.879)GS(0.119)GAAS(0.001)PTGSAVDIR 80.355 0.00023872 67978000.0 42360.0 15556.4 60494.0 290660.0 147313.0 65977.0 37489.1 78279.0 25436.0 59051.0 True False 55829.598857264675 20584.70207801758 59691.8100339226 223652.82765223473 126861.13275747433 61851.44776015941 40825.557273990125 66182.77922247053 26780.495031376824 56983.64246372552 0.9797478090805536 0.36123879043220747 1.0475253503129611 3.924860152536002 2.2262727911475864 1.0854246075886185 0.7164434477837871 1.1614346917995102 0.469968114944998 1.0 15.79826022298022 -6.938344756894813 7.213828714413822 0.8570696115342155 1.7177113234521084 0.1736077717117107 0.9081566862527248 0.4690610566699146 45.408646405468915 0.36387618451832104 0.320225268629328 1.1525379729538339e-07 6.938344756894813 0.860641711917893 TVIRLPS(ph)GSGAASPTGSAVDIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVIRLPSGSGAASPTGSAVDIR 22 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 T(0.004)VIRLPS(0.818)GS(0.171)GAAS(0.004)PT(0.001)GS(0.002)AVDIR;TVIRLPS(0.949)GS(0.047)GAAS(0.003)PT(0.001)GS(0.001)AVDIR 86.439 0.0012902 11238000.0 19748.3 8919.35 5953.8 22817.6 23442.3 31475.1 15753.8 40178.9 25796.2 20453.1 True False 23091.297143295702 9804.804122069407 6095.761171912238 21539.203847657303 18848.949596958613 29824.490347253162 14261.486016365001 39124.24644806348 26173.42062338425 24161.08512334949 0.955722684863192 0.4058097586268572 0.25229666386222194 0.8914832979435027 0.7801367157447253 1.234401939937313 0.590266784109898 1.6193083319032495 1.083288291472059 1.0 14.56039763002865 -6.408147721847156 1.3232326238006549 1.1313257734359465 0.5430040495200188 0.3603699587412039 0.3041792090039294 0.4480329486003779 1.6063360582965787 0.12455135035631709 0.15443969385988518 3.9070797694721593e-07 6.408147721847156 -0.5883217239159277 TVIRLPS(ph)GSGAASPTGSAVDIR ddPTM_PC-9_Lapatinib_30min_R1 2 TVIRLPSGSGAASPTGSAVDIR 22 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 TVIRLPS(1)GSGAASPTGSAVDIR;TVIRLPS(0.991)GS(0.006)GAAS(0.003)PTGSAVDIR 269.34 1.2501999999999996e-86 11651400.0 134621.0 14114.8 19879.9 14689.4 8754.8 9752.9 7433.9 2677.2 18003.1 10350.9 True False 132701.27985353244 14082.118047810733 18245.451360633182 15769.707478401908 8239.859876599052 9335.791202120328 7818.79096764794 2801.5924855991093 15975.401296952488 12140.039273292707 10.930877311531157 1.159973022392973 1.502915348945533 1.2989832341888905 0.6787342026747973 0.7690083196566307 0.6440498907486049 0.23077293429869125 1.3159266570164503 1.0 13.567485468300621 -4.761165373228247 6.649327015897275 0.9187499218568835 11.191780494718106 0.985924637946125 0.3576558186365216 0.013188140883080296 2.9149066395530867 0.09831213875063022 0.6125943320375205 1.7331439152692083e-05 4.761165373228247 10.273030572861222 TVIRLPSGS(ph)GAASPTGSAVDIR ddPTM_PC-9_Lapatinib_30min_R1 1 TVIRLPSGSGAASPTGSAVDIR 22 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 T(0.122)VIRLPS(0.294)GS(0.573)GAAS(0.01)PT(0.001)GSAVDIR 45.638999999999996 0.030292000000000003 17684000.0 133880.0 23801.0 37914.0 31224.0 35327.0 35749.0 28191.0 30120.0 42295.0 23964.0 True False 131970.8466494146 23745.890246829087 34796.857272272326 33520.31712021058 33249.13531555427 34220.09860498921 29650.59204037761 31519.485158465966 37531.29171390517 28106.14546997714 4.695444517299083 0.8448647030662508 1.238051560981287 1.1926330188540737 1.182984530947897 1.2175308293890021 1.0549504937292182 1.121444603356762 1.3353411179770607 1.0 14.778597992903121 -4.758518285585927 24.99999999998855 1.142843525827304 4.6954493141740965 0.9850723645134509 0.1315937213300554 8.141280785005154 69664.01805032951 0.0311960679190883 0.2125549064997415 1.7437399372888685e-05 4.758518285585927 3.5526057883467925 TVIRLPSGSGAAS(ph)PTGSAVDIR ddPTM_PC-9_AZD4547_30min_R2 3 TVIRLPSGSGAASPTGSAVDIR 22 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 TVIRLPSGSGAAS(0.887)PT(0.021)GS(0.092)AVDIR;TVIRLPSGSGAAS(0.997)PT(0.003)GSAVDIR;T(0.001)VIRLPS(0.002)GS(0.001)GAAS(0.956)PT(0.022)GS(0.018)AVDIR 88.541 0.00010039 43776600.0 48693.6 7012.1 45705.5 382780.0 203011.0 60231.8 12113.4 106084.3 23095.8 79742.8 True False 64177.151910200715 9278.624195910827 45099.41520655682 294535.98489204684 174826.42687493676 56465.496024377695 13191.469133234776 89691.40900970028 24316.59683698981 76951.02884381924 0.8339999201369414 0.12057829941095183 0.5860794310897539 3.8275769579356855 2.2719179912430625 0.7337848092841067 0.17142680652143516 1.1655647800595244 0.3160009320517738 1.0 16.231652995225133 -6.914377358202986 11.160136071782631 0.6450856436228246 1.5247314525970321 0.15441528768631296 0.9960310400758688 0.9897288005089417 122.63207165793104 0.39435046675285157 0.3478142016066517 1.2179308796536356e-07 6.914377358202986 0.8796458089742075 TVIRLPSGSGAAS(ph)PTGSAVDIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVIRLPSGSGAASPTGSAVDIR 22 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 TVIRLPSGSGAAS(0.993)PT(0.006)GS(0.001)AVDIR 98.74700000000001 5.5553e-05 7628400.0 20048.0 5924.8 9245.9 19320.0 24025.0 52016.0 17767.0 42956.0 38077.0 22904.0 True False 23441.73043395089 6512.974988360902 9466.357321271013 18237.56303628511 19317.47371490555 49288.18939106532 16083.981138059205 41828.45051564417 38633.80409039325 27056.31389203576 0.8664051772718067 0.24071922784271244 0.34987609025549893 0.6740594121231526 0.7139728564648196 1.8216889997559385 0.5944631335310481 1.5459774262877954 1.4279034551622871 1.0 14.72367768183815 -6.570645644103389 9.607981064652732 1.2703928991808786 0.5229700469637544 0.5196746988464501 0.3442592165784763 0.2929548626989167 56.25442639864621 0.11021587634536127 0.1102810664503054 2.6875364052447014e-07 6.570645644103389 -0.7474228522171242 TVIRLPSGSGAAS(ph)PTGSAVDIR ddPTM_PC-9_Lapatinib_30min_R1 3 TVIRLPSGSGAASPTGSAVDIR 22 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 TVIRLPSGSGAAS(0.978)PT(0.003)GS(0.018)AVDIR;TVIRLPS(0.001)GS(0.002)GAAS(0.799)PT(0.182)GS(0.017)AVDIR;T(0.004)VIRLPS(0.022)GS(0.009)GAAS(0.415)PT(0.415)GS(0.135)AVDIR 106.88 1.5585e-05 59303800.0 1474880.0 52832.9 123776.0 68775.3 22350.5 23917.9 13820.4 6726.3 45293.7 15367.3 True False 1453847.940740132 52710.568666093684 113599.61506917723 73833.26498967526 21035.88753277369 22894.987172348083 14535.952688263449 7038.828453565396 40192.246542194225 18023.51732935988 80.66394112606692 2.9245439557033315 6.302854930770154 4.096495908121254 1.1671355345555516 1.2702840824000927 0.8064992211361947 0.3905357830515863 2.229989064161301 1.0 14.137592963311832 -4.761399374531561 8.595481359997164 2.256150971044747 81.36256612081785 0.9947735565335385 1.7053398257243801 0.006115912687847848 5.165660417212764 0.4865242071568746 2.80832359146736 1.7322103351464856e-05 4.761399374531561 79.1064151497731 TVKQEQINTEPLEDTVLS(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 1 TVKQEQINTEPLEDTVLSPTK 21 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 TVKQEQINTEPLEDT(0.039)VLS(0.735)PT(0.226)K 147.26 5.9416e-05 7774400.0 33055.0 7029.0 29813.0 122870.0 71897.0 31214.0 11899.0 16733.0 13626.0 44536.0 True False 43565.80241328809 9300.98679041331 29417.660140531832 94544.21982257652 61915.34258255637 29262.18364559795 12957.987948582615 14147.299336087559 14346.242541969672 42976.808195703394 1.0137049316203892 0.21641874259389918 0.6845008127772705 2.199889284286788 1.4406687044001176 0.6808831291599602 0.3015111752733208 0.32918450508620917 0.3338135879389 1.0 15.391270720127599 -6.964861276787875 6.722903557890641 0.4420479712849718 1.0971372211436798 0.24644501881266745 0.5141013128480619 0.2878659401218682 38.47767133100978 0.20396813024995042 0.17793007405387995 1.0842731994268933e-07 6.964861276787875 0.655089249858708 TVKQEQINTEPLEDTVLS(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVKQEQINTEPLEDTVLSPTK 21 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 TVKQEQINTEPLEDT(0.092)VLS(0.619)PT(0.289)K 89.92299999999999 0.00020065 4183000.0 21624.0 3195.9 10077.0 31916.0 21701.0 59222.0 24764.0 85288.0 51341.0 26586.0 True False 25284.516106532014 3513.167831032709 10317.273897235322 30127.8499930681 17448.84483193195 56116.29406562737 22418.17464416604 83049.28037010565 52091.76499737057 31405.831345339793 0.8050898518973261 0.11186355146602467 0.32851459284061485 0.9593075140021304 0.5555925152900347 1.7868112914627328 0.7138220414436696 2.644390446375783 1.6586653741009882 1.0 14.9387448390459 -6.705906346830955 1.0884021136092181 1.719842710242476 0.4187683441468983 0.4372667244599767 0.545288062364507 0.41626979699226524 1.0529432627183701 0.27685808107001736 0.2646144242234662 1.9683106991063663e-07 6.705906346830955 -1.3010743660955777 TVKQEQINTEPLEDTVLS(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 2 TVKQEQINTEPLEDTVLSPTK 21 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 TVKQEQINTEPLEDT(0.145)VLS(0.664)PT(0.191)K;TVKQEQINTEPLEDT(0.105)VLS(0.673)PT(0.222)K 139.0 5.7523000000000005e-05 9953100.0 515410.0 55991.0 117633.0 94158.0 56494.0 62532.0 28877.0 22589.0 89929.0 39741.0 True False 508060.1588853829 55861.356279576794 107961.66881651118 101082.69342188013 53171.1339914774 59857.65212921166 30372.109763753848 23638.567405198806 79800.24902564797 46610.17889844611 10.900197572558998 1.198479765574105 2.3162680635004045 2.1686828030014285 1.1407622808598579 1.284218459226021 0.6516196779662305 0.5071546165206173 1.7120777244712173 1.0 15.508357429766056 -4.760910379896929 24.999268383006623 1.3439524022094356 10.900208429352965 0.9634658079866419 0.5590145088310084 2.35994601494377 111422.49531516644 0.1542719922854409 0.8865648414068051 1.7341618188476336e-05 4.760910379896929 9.55625602714353 TVLDT(ph)SYALIGETVNNYR ddPTM_PC-9_AZD4547_30min_R2 2 TVLDTSYALIGETVNNYR 18 0 H0Y8J2;Q03188;Q03188-2 H0Y8J2 CENPC Centromere protein C 1 TVLDT(0.545)S(0.455)YALIGETVNNYR;T(0.001)VLDT(0.5)S(0.5)YALIGETVNNYR 145.33 9.8438e-05 3493800.0 23258.9 21349.4 27926.0 36029.9 25187.8 32314.5 22239.5 34903.1 28752.5 30440.1 True False 30654.746384826118 28250.17603972826 27555.682993475744 27723.76321140596 21690.90874307571 30293.869206627613 24218.772416379776 29509.627888447823 30272.29845060787 29374.40136424534 1.0435871017320277 0.9617277196366802 0.9380849213498067 0.9438069177182095 0.7384289631678413 1.0313016708317144 0.8244856504840633 1.00460354995922 1.0305673322573803 1.0 14.842271830116113 -7.966121169934162 24.934556996110665 1.016051119785845 0.9245252552037877 0.17610143751488294 0.08522013139073539 282.76390140648 208111.84345429583 0.04584838164878891 0.02202472042279191 1.0811322688960873e-08 7.966121169934162 -0.09152586458205736 TVLDT(ph)SYALIGETVNNYR ddPTM_PC-9_Lapatinib_30min_R1 1 TVLDTSYALIGETVNNYR 18 0 H0Y8J2;Q03188;Q03188-2 H0Y8J2 CENPC Centromere protein C 1 TVLDT(0.624)S(0.376)YALIGETVNNYR 96.773 0.0019897 4041600.0 11658.0 17806.0 18265.0 15791.0 17396.0 14229.0 13763.0 13372.0 17551.0 10903.0 True False 11491.754782184635 17764.771300997378 16763.32220493892 16952.32281723178 16372.801481851913 13620.458839419045 14475.580797123797 13993.311936886023 15574.221559776563 12787.56902266571 0.8986661000081978 1.3892219286957261 1.3109076615912114 1.3256876883467161 1.2803685714486819 1.0651327719347636 1.1320041183328997 1.09429023703279 1.2179188657493514 1.0 13.642454406686332 -6.756253933560721 24.99277217086848 1.1096457659657717 1.257798523795989 0.2052516461111379 0.1344059183465279 197.18573391623832 950393.05479311 0.0440168445272099 0.042759593849263755 1.752855301291519e-07 6.756253933560721 0.1481527578302173 TVLEGSTAST(ph)SPADHSALPNQSLTVR ddPTM_PC-9_AZD4547_30min_R2 2 TVLEGSTASTSPADHSALPNQSLTVR 26 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 T(0.001)VLEGS(0.014)T(0.046)AS(0.122)T(0.409)S(0.409)PADHSALPNQSLTVR;TVLEGS(0.031)T(0.092)AS(0.092)T(0.718)S(0.066)PADHSALPNQSLTVR 95.052 9.831799999999999e-09 42027000.0 12343.900000000001 5794.4 22476.7 35195.0 30061.0 22774.5 10755.6 29796.0 18998.5 20792.5 True False 16269.003430929877 7667.326484332181 22178.644271985104 27081.33650732954 25887.54904063074 21350.406914739237 11712.82756364192 25191.712843964902 20002.721923793535 20064.56090374445 0.8108327667361889 0.3821327823277361 1.1053640485023584 1.3497099008169982 1.2902125874979704 1.0640854298862241 0.5837569842585527 1.2555327258252447 0.9969179998382435 1.0 14.292361963829734 -5.276561090740281 24.434792672000146 1.0885727696945164 0.5964827887730453 0.4280538148636237 0.22373757435294964 493.85660661827126 798010.7047781125 0.06113161078528455 0.1280984123664823 5.289795822017988e-06 5.276561090740281 -0.49208998092147116 TVLEGSTAST(ph)SPADHSALPNQSLTVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVLEGSTASTSPADHSALPNQSLTVR 26 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 T(0.002)VLEGS(0.046)T(0.141)AS(0.141)T(0.53)S(0.141)PADHSALPNQSLTVR 84.515 2.9899e-06 7434700.0 2613.5 3864.1 2972.3 4047.6 7856.8 7666.2 3329.3 3860.8 4480.0 2499.1 True False 3055.9139310220817 4247.702311052751 3043.170904510522 3820.826094496253 6317.3164405107145 7264.1709764262 3013.9246019553407 3759.458090855736 4545.5115246726855 2952.167047135284 1.035142619719799 1.4388421262186448 1.0308261205826907 1.294244544259071 2.1398912526446954 2.4606232846732663 1.0209193971187995 1.2734571014549563 1.5397202976991247 1.0 11.527558642664445 -6.019949346298379 24.322418828974477 1.6133168169765943 1.1898620123842123 0.14587501197222164 0.44209091643274856 1053.7723153572979 1284769.4495840468 0.13869792781074422 0.18171371654297172 9.551039775602664e-07 6.019949346298379 -0.42345480459238205 TVLEGSTAST(ph)SPADHSALPNQSLTVR ddPTM_PC-9_Lapatinib_30min_R1 2 TVLEGSTASTSPADHSALPNQSLTVR 26 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 TVLEGS(0.004)T(0.069)AS(0.26)T(0.622)S(0.045)PADHSALPNQSLTVR;TVLEGSTAS(0.004)T(0.776)S(0.22)PADHSALPNQSLTVR 111.01 6.6176e-10 30888000.0 14002.9 13298.8 22203.0 6743.0 21172.3 18639.3 16695.9 8461.8 18442.6 13785.4 True False 13803.216078182646 13268.007445675832 20377.555046058504 7238.902713988589 19926.98694034337 17842.140589330502 17560.332008333895 8854.966119319637 16365.400178812317 16168.18802210913 0.8537268405901446 0.8206242670812922 1.2603487180006374 0.44772504526108786 1.2324811483571494 1.103533714781912 1.0861038963872194 0.5476783240775618 1.0121975422622194 1.0 13.980870383778743 -1.5231656615846432 0.0077306653371149794 1.5819600382717955 0.2204856522592102 0.005121834813313408 0.2568060322162999 383625.7348347662 230.2183076580656 18075.230699740885 22714.477159089103 0.029980187069262167 1.5231656615846432 -1.3614743860125853 TVLEGSTASTS(ph)PADHSALPNQSLTVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVLEGSTASTSPADHSALPNQSLTVR 26 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 TVLEGSTAS(0.001)T(0.198)S(0.8)PADHSALPNQSLTVR 108.52 3.3721e-10 8004600.0 3178.6 2119.0 6524.2 2955.0 5730.2 7696.8 5874.9 5022.8 2870.4 5107.2 True False 3716.6741997883237 2329.360316016869 6679.761671166287 2789.440930239261 4607.408444584879 7293.166258557976 5318.38694140733 4890.956822096509 2912.3741697367122 6033.094931427044 0.6160476906185854 0.38609707662363796 1.1071865679372432 0.46235654534603154 0.7636890347248458 1.2088598540969553 0.8815354311272772 0.8106878604908049 0.4827330255597074 1.0 12.558682568173781 -5.242946170693836 24.990702024894027 0.8313669303872192 0.5010723653671648 0.2534141526164957 0.2320974539232522 1182.62901985796 1598133.8995091447 0.05948889705480055 0.15675188243941993 5.715494738717415e-06 5.242946170693836 -0.3302945650200544 TVLPTVPES(ph)PEEEVK ddPTM_PC-9_AZD4547_30min_R2 3 TVLPTVPESPEEEVK 15 0 O75152;E9PBY7;E9PQ61;A0A1W2PPR9 O75152 ZC3H11A Zinc finger CCCH domain-containing protein 11A 1 TVLPTVPES(1)PEEEVK;TVLPT(0.013)VPES(0.987)PEEEVK;TVLPTVPES(1)PEEEVK 184.0 5.0826e-07 14949700.0 83765.0 79912.0 80161.0 84387.0 95909.0 96178.0 82732.0 100736.0 93574.0 86756.0 True False 110400.52757976313 105741.99123566778 79098.01276373313 64932.88091615343 82593.69085984655 90163.97445589518 90094.98772687942 85169.56588299258 98520.1306048927 83718.69884647116 1.3187081154023053 1.2630630037571937 0.9448070007488799 0.7756078607388728 0.9865620464469028 1.0769872883624696 1.0761632582477365 1.0173302626117269 1.1767995915173668 1.0 16.353262268993873 -5.201097540054569 5.774869636996015 1.0035464496794053 1.2985060047623147 0.5697283467693308 0.09887006359981974 0.16814498041452727 11.638734813094896 0.027941827828978395 0.0760098455644775 6.293648152478324e-06 5.201097540054569 0.2949595550829094 TVLPTVPES(ph)PEEEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TVLPTVPESPEEEVK 15 0 O75152;E9PBY7;E9PQ61;A0A1W2PPR9 O75152 ZC3H11A Zinc finger CCCH domain-containing protein 11A 1 TVLPT(0.002)VPES(0.998)PEEEVK;TVLPT(0.006)VPES(0.994)PEEEVK;TVLPT(0.001)VPES(0.999)PEEEVK;TVLPT(0.003)VPES(0.997)PEEEVK 166.9 1.5784e-20 11018200.0 153488.0 169766.0 147638.0 171671.0 170026.0 138367.0 177973.0 146093.0 132741.0 125238.0 True False 179470.48687381533 186619.2465355919 151158.24984023275 162052.83043489148 136710.62584185333 131110.79093881775 161114.10902706216 142258.21354832893 134682.08600370018 147942.65801653764 1.2131084386340645 1.2614295906102406 1.0217353930692232 1.0953759558434901 0.924078475233095 0.8862270875528115 1.089030785218501 0.9615767044852387 0.9103668124486777 1.0 17.17467857579488 -5.431588649011887 1.3554267806969162 0.9678693896276725 1.2618516143322773 0.6860320673599984 0.06777499731953839 0.30750192969400947 0.9811512362548361 0.021581394728966804 0.08920724485122314 3.701786361236679e-06 5.431588649011887 0.2939822247046048 TVLPTVPES(ph)PEEEVK ddPTM_PC-9_Lapatinib_30min_R1 3 TVLPTVPESPEEEVK 15 0 O75152;E9PBY7;E9PQ61;A0A1W2PPR9 O75152 ZC3H11A Zinc finger CCCH domain-containing protein 11A 1 TVLPT(0.007)VPES(0.993)PEEEVK;TVLPTVPES(1)PEEEVK;T(0.002)VLPT(0.286)VPES(0.712)PEEEVK 190.87 1.2434000000000001e-07 12278500.0 104701.0 108472.0 102109.0 101326.0 128020.0 116555.0 120847.0 111027.0 111208.0 99005.0 True False 103207.94454018837 108220.83974849973 93713.99217213837 108777.85205362702 120490.11529700393 111570.21435297544 127103.86635108783 116185.71974399107 98682.58396784398 116117.88233412977 0.8888204165074851 0.9319911590972159 0.8070590876130165 0.9367881145181258 1.0376533990715835 0.9608357654330244 1.0946106129058213 1.0005842115658474 0.8498482919614773 1.0 16.82523064102567 -6.000019243506641 24.99999999965546 0.993684956423876 0.8799541800218827 0.38549067485747057 0.0648651669330354 0.7212915455011796 939352.2886668139 0.018454771323569368 0.02705943290440871 9.999556911701376e-07 6.000019243506641 -0.11373077640199325 TVMDGGLES(ph)DGPNMTENGLEDESRPQR ddPTM_PC-9_AZD4547_30min_R2 2 TVMDGGLESDGPNMTENGLEDESRPQR 27 1 P51116 P51116 FXR2 Fragile X mental retardation syndrome-related protein 2 1 T(0.006)VMDGGLES(0.895)DGPNMT(0.099)ENGLEDESRPQR;T(0.042)VMDGGLES(0.657)DGPNMT(0.3)ENGLEDESRPQR 69.704 0.00011092 23401700.0 40783.0 41148.0 51254.0 46434.0 43006.0 61167.0 51251.0 58501.0 47894.0 46146.0 True False 53751.145660902395 54448.28630700337 50574.33847123131 35729.358698148586 37035.35923759571 57342.21782053849 55812.23971365725 49461.0146692439 50425.579062461096 44530.44258574923 1.20706515677219 1.2227205288192684 1.1357250351564272 0.8023580414532597 0.8316863046281036 1.2877082393717174 1.2533502133104433 1.1107236262922877 1.132384412424377 1.0 15.442504330272383 -6.793374999206434 24.999995396969055 1.169785724018573 1.0421921795774436 0.12898104313300662 0.14998615123641026 446.23960098594205 349324.3587855279 0.05909278581590074 0.05211917609592916 1.6092554951420056e-07 6.793374999206434 -0.12759354444112936 TVMDGGLES(ph)DGPNMTENGLEDESRPQR ddPTM_PC-9_Lapatinib_30min_R1 3 TVMDGGLESDGPNMTENGLEDESRPQR 27 1 P51116 P51116 FXR2 Fragile X mental retardation syndrome-related protein 2 1 T(0.029)VMDGGLES(0.886)DGPNMT(0.085)ENGLEDESRPQR;T(0.027)VMDGGLES(0.97)DGPNMT(0.003)ENGLEDESRPQR;T(0.025)VMDGGLES(0.745)DGPNMT(0.229)ENGLEDESRPQR 63.536 0.00032728 29693600.0 25888.1 40124.3 37568.0 34277.7 46121.0 45008.0 48533.0 48347.0 44581.0 47806.0 True False 25518.930946703887 40031.39464857967 34479.3040566737 36798.596405055134 43408.25345737477 43083.11275877242 51045.8012662072 50593.37811940086 39559.818321257946 56069.20340250912 0.455132753777663 0.7139640340741535 0.6149419282659319 0.6563067454496487 0.7741906576727329 0.7683917399269566 0.910407107084437 0.9023380938052847 0.7055534218538162 1.0 15.774920952556574 -4.083516227494231 0.20770506800388538 0.9828017155834816 6.414659849875671e-13 0.7056964144460273 0.08220234544126935 10.436352044508169 0.3219300314032406 0.15944490940564518 2.768513584175556 8.25056656507157e-05 4.083516227494231 -0.9828017155828401 down TVNSGGSSEPSPT(ph)EVDVSR ddPTM_PC-9_AZD4547_30min_R2 1 TVNSGGSSEPSPTEVDVSR 19 0 Q6PIJ6-2;Q6PIJ6 Q6PIJ6-2 FBXO38 F-box only protein 38 1 TVNSGGSS(0.001)EPS(0.058)PT(0.941)EVDVSR 160.05 1.2903e-20 0.0 26329.0 26229.0 22742.0 32198.0 28907.0 31854.0 28409.0 28724.0 25640.0 30543.0 True False 34701.07432277907 34707.01131394944 22440.426220641166 24775.248554141104 24893.76202114075 29862.164344424848 30937.345964474614 24285.36581185555 26995.278054902552 29473.698866565646 1.1773572933576808 1.1775587268865109 0.7613712253163148 0.8405883722400934 0.8446093628709669 1.0131800721591775 1.049659430414053 0.8239673588917734 0.915910764275516 1.0 14.847140505555629 -5.241161202607709 24.84977539821731 0.9042808731352195 1.177458104083426 0.605268033897978 0.08762547919305888 527.336180532619 646218.5970828456 0.023730893213483588 0.06261510385470857 5.739033996414665e-06 5.241161202607709 0.27317723094820645 TVNVS(ph)SIR ddPTM_PC-9_AZD4547_30min_R2 1 TVNVSSIR 8 0 Q92674 Q92674 CENPI Centromere protein I 1 T(0.009)VNVS(0.765)S(0.226)IR 82.831 0.038826 0.0 46430.0 43909.0 76244.0 130310.0 103690.0 68417.0 57950.0 108920.0 72919.0 85974.0 True False 61193.77419600568 58101.72556270567 75232.9547430554 100269.04276943061 89294.43331968348 64138.87417443691 63107.4377359747 92088.91673260363 76773.34947291098 82964.07642844913 0.73759362883743 0.7003238999811497 0.9068136232184625 1.2085838484070373 1.0763023848845452 0.7730921253580436 0.7606597994301856 1.1099854382399357 0.9253806319307702 1.0 16.34019916206394 -5.356291067758978 4.5130036296496145 0.9753152639654374 0.7194705118056747 0.37313197213753646 0.13222677580983502 0.24383714689687985 8.370189557855472 0.03838640206220288 0.08496538044335764 4.402596989098983e-06 5.356291067758978 -0.25584475215976277 TVNVS(ph)SIR ddPTM_PC-9_Lapatinib_30min_R1 2 TVNVSSIR 8 0 Q92674 Q92674 CENPI Centromere protein I 1 TVNVS(0.84)S(0.16)IR;T(0.003)VNVS(0.772)S(0.225)IR 114.4 0.004508399999999999 0.0 29308.0 115915.0 197715.0 152464.0 165768.0 136675.0 123563.0 121202.0 146089.0 124434.0 True False 28890.062545571054 115646.60593929635 181459.63590197102 163676.7111649943 156017.8521524274 130829.72885498611 129960.4875415977 126833.48738965452 129634.91843463035 145942.25110211736 0.19795544009634583 0.792413472219071 1.2433660199951402 1.12151696941051 1.0690382735240944 0.8964486148938675 0.8904925514042055 0.8690662671833653 0.8882617436394304 1.0 17.155038086487487 -4.810746075375208 3.4537819232141036 0.9936699082504762 0.12495183609280082 0.8106978567444741 0.11602144672436852 0.12470681598634098 2.4601070764891806 0.03322795166530542 0.2735427120434058 1.5461581878034982e-05 4.810746075375208 -0.8687180721576754 down TVPS(ph)TPTLVVPHR ddPTM_PC-9_AZD4547_30min_R2 1 TVPSTPTLVVPHR 13 0 P12270 P12270 TPR Nucleoprotein TPR 1 TVPS(0.512)T(0.488)PTLVVPHR 132.44 3.18e-05 67116000.0 80519.0 118470.0 106040.0 94513.0 100600.0 120200.0 111910.0 157610.0 116570.0 90955.0 True False 106122.36710075743 156763.11069288163 104633.84031469483 72724.48806129381 86633.42648240083 112683.87499842634 121869.77320160372 133254.99601749613 122731.65221762848 87770.69313454724 1.2090865790256227 1.786053010343363 1.1921273101295597 0.828573701130644 0.9870427518396938 1.2838439685748941 1.3885018888341765 1.5182174283758265 1.39832155625669 1.0 16.421451680044548 -7.0002857833304795 24.995854372791644 1.3646918752186454 1.2043145536850073 0.04167725042825188 0.2617722843923512 32.57145279771938 2849123.499941902 0.10171687608798048 0.0887177979495164 9.993421760245373e-08 7.0002857833304795 -0.16037732153363815 TVPS(ph)TPTLVVPHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVPSTPTLVVPHR 13 0 P12270 P12270 TPR Nucleoprotein TPR 1 TVPS(0.605)T(0.395)PTLVVPHR;T(0.001)VPS(0.576)T(0.152)PT(0.271)LVVPHR 109.83 0.00042163 35945000.0 42469.0 41442.0 44464.0 48964.0 99510.0 92151.0 132583.0 120801.0 103881.0 111574.0 True False 49658.16289901541 45556.08787936343 45524.19039065906 46220.70582342981 80011.72983851204 87318.43933743589 120023.77842220434 117630.10174923949 105400.06310145622 131801.48298070213 0.3767648267378461 0.3456416942291429 0.34539968262211845 0.3506842622567249 0.607062439883374 0.6624996727102131 0.9106405763262752 0.8924793491622733 0.7996879907405025 1.0 17.00800707753595 -6.7261329597705535 1.2341104752700933 0.9021861281271145 0.3413920623677425 0.9425769285202262 0.05961591044588754 0.09474136597405765 0.30428712802796426 0.028534484715052173 0.026592459467529833 1.8787415497954342e-07 6.7261329597705535 -0.560794065759372 down TVPS(ph)TPTLVVPHR ddPTM_PC-9_Lapatinib_30min_R1 2 TVPSTPTLVVPHR 13 0 P12270 P12270 TPR Nucleoprotein TPR 1 T(0.006)VPS(0.611)T(0.383)PT(0.001)LVVPHR;T(0.003)VPS(0.789)T(0.203)PT(0.004)LVVPHR 98.439 0.0015634 107042000.0 24449.8 23951.0 32694.0 35508.0 87593.0 140882.0 152928.0 135444.0 168083.0 129986.0 True False 24101.141368455817 23895.54293104505 30006.025522489632 38119.376771215626 82440.95195446388 134856.80527198222 160845.86355754925 141737.2227026316 149151.72254754265 152453.90690454212 0.15808805335206377 0.15673945926493746 0.1968203119994667 0.2500387005174212 0.5407598508189342 0.8845742822217196 1.0550458615551368 0.9297054144462124 0.9783397852895491 1.0 17.21801359690376 -6.551622643182886 1.7017628009021264 0.9920975032581715 0.16904999867275708 0.9917879196300651 0.03363895562752926 0.030667245302020557 0.1808178497351335 0.014094840768740907 0.015083626567754601 2.8078723278588435e-07 6.551622643182886 -0.8230475045854144 down TVPST(ph)PTLVVPHR ddPTM_PC-9_AZD4547_30min_R2 4 TVPSTPTLVVPHR 13 0 P12270 P12270 TPR Nucleoprotein TPR 1 TVPS(0.031)T(0.969)PTLVVPHR;TVPS(0.072)T(0.927)PTLVVPHR;TVPS(0.032)T(0.968)PTLVVPHR;TVPS(0.032)T(0.908)PT(0.06)LVVPHR 199.4 1.3259999999999999e-06 230556000.0 183172.0 221207.0 229868.0 229277.0 216783.0 274691.0 188941.0 284528.0 212495.0 204460.0 True False 241416.8857857148 292707.8368113465 226819.80012691685 176420.7299443386 186686.42239696145 257514.52834602867 205756.3829727831 240560.7354029953 223727.05188285955 197301.9176327804 1.2235911778366062 1.4835529239818959 1.149607681710805 0.8941663216507302 0.9461966950793831 1.3051800582360096 1.0428503961919833 1.2192518871039486 1.1339324755031617 1.0 17.590045452524933 -5.4372639587104485 6.474759925277984 1.0841916556515239 1.3493944247009462 0.4137697131711099 0.1294259409381637 0.23439150143171703 14.656577661105235 0.034931769543460583 0.07325750436254175 3.6537265522094577e-06 5.4372639587104485 0.2652027690494223 TVPST(ph)PTLVVPHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TVPSTPTLVVPHR 13 0 P12270 P12270 TPR Nucleoprotein TPR 1 TVPS(0.04)T(0.95)PT(0.01)LVVPHR;TVPS(0.035)T(0.965)PTLVVPHR;TVPS(0.148)T(0.852)PTLVVPHR 152.11 0.00026289 67243000.0 74258.0 96114.0 78151.0 77906.0 210729.0 185305.0 253875.0 223488.0 194358.0 219682.0 True False 86828.41273764588 105655.56272470298 80014.41622931784 73541.17939465978 169438.16518078407 175587.27958919122 229826.12210417003 217621.67680510908 197200.1180607885 259508.60759824468 0.33458779476042777 0.4071370260221674 0.30833049034424037 0.28338628177032077 0.652919248995 0.6766144723069252 0.8856204201903497 0.8385913624183812 0.7598981778904291 1.0 17.98542286632768 -6.5909781475888405 1.596869420237868 0.8510962343020617 0.3323960372572977 0.8954455055286633 0.08074237128150603 0.11225415070510816 0.5879558159167592 0.03223392686072213 0.03356831747520159 2.5646130770002105e-07 6.5909781475888405 -0.518700197044764 down TVPST(ph)PTLVVPHR ddPTM_PC-9_Lapatinib_30min_R1 2 TVPSTPTLVVPHR 13 0 P12270 P12270 TPR Nucleoprotein TPR 1 T(0.001)VPS(0.243)T(0.756)PTLVVPHR;T(0.001)VPS(0.343)T(0.656)PTLVVPHR 119.77 0.00046719999999999997 85650000.0 30712.6 28655.0 28492.0 35887.0 103789.0 167060.0 196969.0 170850.0 205590.0 164972.0 True False 30274.632691998933 28588.651108057944 26149.49774230055 38526.249695522565 97684.33507702494 159915.23323588062 207167.09104328114 178788.31471858983 182434.2892413232 193487.19038862785 0.15646840822480781 0.14775474826336737 0.135148469982835 0.19911524694808394 0.5048620266841515 0.8264900271417637 1.07070184143548 0.9240317891819367 0.9428752822080656 1.0 17.561878531894223 -6.597706515224861 1.74643824463188 0.9818590954046473 0.14402116693590394 0.9877284970738905 0.04206098430061427 0.036144560155619766 0.22557837512184079 0.01743864835904832 0.018003403166912332 2.5251866506678306e-07 6.597706515224861 -0.8378379284687434 down TVQPVAMGPDGLPVDASSVS(ph)NNYIQTLGR ddPTM_PC-9_AZD4547_30min_R2 2 TVQPVAMGPDGLPVDASSVSNNYIQTLGR 29 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;E9PKL1 O60716 CTNND1 Catenin delta-1 1 TVQPVAMGPDGLPVDAS(0.009)S(0.021)VS(0.938)NNY(0.005)IQT(0.027)LGR;TVQPVAMGPDGLPVDAS(0.142)S(0.158)VS(0.695)NNY(0.002)IQT(0.003)LGR 105.62 1.9480999999999996e-11 8473800.0 11340.1 14885.4 21211.7 39128.0 40498.0 36245.0 23960.1 34729.0 29727.0 33048.0 True False 14946.015911266939 19696.81445013776 20930.41899852144 30107.64412157381 34875.551746364494 33978.594420282476 26092.50248313591 29362.431043027853 31298.308531126688 31890.999579028306 0.46865937438648114 0.6176292593566272 0.6563111622341683 0.9440796625695219 1.0935860338883465 1.0654603138443794 0.8181776309167331 0.9207121579950961 0.9814150996919089 1.0 14.960861697117885 -5.6740051016638455 2.7064991130623137 0.9774956670820647 0.5521697296629606 0.8441009528122213 0.0786602497232215 0.1095295285917712 1.6170437992031923 0.025122908286101676 0.04838470781826663 2.1183362509743743e-06 5.6740051016638455 -0.42532593741910407 TVQPVAMGPDGLPVDASSVS(ph)NNYIQTLGR ddPTM_PC-9_Lapatinib_30min_R1 2 TVQPVAMGPDGLPVDASSVSNNYIQTLGR 29 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;E9PKL1 O60716 CTNND1 Catenin delta-1 1 TVQPVAMGPDGLPVDAS(0.005)S(0.049)VS(0.916)NNY(0.016)IQT(0.014)LGR;TVQPVAMGPDGLPVDAS(0.018)S(0.065)VS(0.896)NNY(0.003)IQT(0.018)LGR 106.11 1.8304000000000003e-11 4705500.0 20837.0 12003.400000000001 18177.5 16481.0 16017.900000000001 12937.8 9973.6 9842.8 19658.6 11914.4 True False 20539.860558962195 11975.606864786694 16683.01611717914 17693.067719004302 15075.758614403056 12384.480453484839 10489.984206800402 10300.132420907994 17444.441453764644 13973.788165059923 1.4698849242841743 0.8570050385285299 1.1938792774097846 1.2661611518660394 1.0788598221417511 0.8862650776724245 0.750690083668906 0.7371038045833883 1.2483688208028476 1.0 13.770435554634757 -6.628818404251596 3.8815053051515678 0.8974742623380236 1.1725462801085145 0.2954135499230147 0.19468680306875166 0.2874447526221797 8.141974706076246 0.0656791956576101 0.06555181139946414 2.3506155009591714e-07 6.628818404251596 0.27507201777049084 TVQPVAMGPDGLPVDASSVSNNY(ph)IQTLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVQPVAMGPDGLPVDASSVSNNYIQTLGR 29 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16;E9PKL1 O60716 CTNND1 Catenin delta-1 1 TVQPVAMGPDGLPVDAS(0.009)S(0.031)VS(0.117)NNY(0.831)IQT(0.012)LGR 104.65 1.0297e-05 0.0 4034.0 4679.4 8078.9 7064.0 8785.6 6924.9 7393.0 4812.1 4873.7 4379.9 True False 4716.876524868214 5143.939906922764 8271.531615398872 6668.226981796997 7064.124747957301 6561.74605341027 6692.681519315119 4685.787473841402 4944.968642365458 5173.941198730675 0.911660249642073 0.9942014625494253 1.598690688140818 1.2888099662657388 1.3653276055186607 1.2682297307553603 1.2935364477967082 0.9056514741588034 0.9557450408556266 1.0 12.337047942708377 -7.760805896115944 24.99994812910602 0.9480236352505462 1.2567934015296458 0.35482239836146356 0.1799464820658418 19.202703624116264 757929.2674151686 0.09688040679038516 0.05160653817048583 1.734579078538433e-08 7.760805896115944 0.3087697662790996 TVQS(ph)PNSSVPSPGLAGPVTMTSVHPPIR ddPTM_PC-9_AZD4547_30min_R2 2 TVQSPNSSVPSPGLAGPVTMTSVHPPIR 28 0 O15164-2;O15164 O15164-2 TRIM24 Transcription intermediary factor 1-alpha 1 T(0.147)VQS(0.434)PNS(0.209)S(0.209)VPS(0.001)PGLAGPVTMTSVHPPIR;T(0.204)VQS(0.671)PNS(0.063)S(0.063)VPSPGLAGPVTMTSVHPPIR 107.58 1.5575e-05 6045400.0 7547.1 6871.799999999999 13631.4 28871.0 16004.6 17620.0 13550.0 17820.5 9078.3 14260.0 True False 9946.920810568048 9092.974964626857 13450.638729401464 22215.23700250351 13782.63754950529 16518.218614577938 14755.923750171814 15066.751199351487 9558.160404283219 13760.761740406195 0.7228466707159507 0.6607900882352206 0.9774632380928371 1.614390062235592 1.0015897237022033 1.2003854820096862 1.0723188169767879 1.0949067706848286 0.6945952981815873 1.0 13.748272713593016 -5.381701766021883 4.636096257259977 1.1122670307765896 0.6958671641196792 0.3480830616196059 0.21625612659854998 0.22938440173951802 7.589587671523651 0.05795979630959168 0.12635575064836685 4.152390932188146e-06 5.381701766021883 -0.4163998666569104 TVQSLEIDLDSMR ddPTM_PC-9_Lapatinib_30min_R1 3 TVQSLEIDLDSMR 13 0 P05783;F8VZY9;CON__H-INV:HIT000015463 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ;; 274.59 6.0577e-68 29597500.0 54569.7 44569.0 61074.6 48472.1 57745.1 56413.9 51818.2 49347.8 50754.7 47738.1 False True 53791.52607114264 44465.803218811205 56053.28214277374 52036.89993218546 54348.64674923471 54001.209004223965 54501.09284760015 51640.67894100092 45038.17121531487 55989.566977980154 0.9607419555914413 0.7941801592482208 1.0011379828105949 0.9294035074900789 0.9706923929347266 0.9644869913971976 0.9734151519520521 0.9223268142314874 0.804402920869663 1.0 15.772870401873325 -5.276218582532966 24.983894011072003 0.9449257877077304 0.8774610394936114 0.14942856802805116 0.06513135632403859 1311.0808389585304 2216351.7685053744 0.016662175661127772 0.03491634453221889 5.293969287693394e-06 5.276218582532966 -0.06746474821411896 TVQSQIGPPLTDSRPLGS(ph)PPNATR ddPTM_PC-9_AZD4547_30min_R2 1 TVQSQIGPPLTDSRPLGSPPNATR 24 1 Q96QT6;C9J9G2;Q96QT6-4;Q96QT6-2;Q96QT6-5;Q96QT6-3;K7EPF7 Q96QT6 PHF12 PHD finger protein 12 1 T(0.001)VQS(0.002)QIGPPLT(0.004)DS(0.388)RPLGS(0.531)PPNAT(0.075)R 48.913000000000004 0.016431 9930600.0 9624.7 7759.7 11340.0 13768.0 13319.0 11519.0 9163.4 12466.0 9189.1 11000.0 True False 12685.154393803487 10267.871275796006 11189.62419057563 10594.000313479566 11469.886752674916 10798.715109042181 9978.924848142018 10539.666140182127 9674.817066080544 10614.893348139414 1.1950336171796723 0.9673080019777839 1.054143816954784 0.9980317244860958 1.0805465845481497 1.0173173441196173 0.9400871512186348 0.9929130509850603 0.9114379908278921 1.0 13.373802255561149 -7.067730453026222 4.400653836119054 0.9612038338360265 1.0503729387491183 0.3605785928036601 0.06082179636886128 0.263005684651761 9.863637040008447 0.022473048660752858 0.017573151872914923 8.5559757890695e-08 7.067730453026222 0.08916910491309182 TVQSQIGPPLTDSRPLGSPPNAT(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 TVQSQIGPPLTDSRPLGSPPNATR 24 1 Q96QT6;C9J9G2;Q96QT6-4;Q96QT6-2;Q96QT6-5;Q96QT6-3;K7EPF7 Q96QT6 PHF12 PHD finger protein 12 1 TVQSQIGPPLTDS(0.027)RPLGS(0.354)PPNAT(0.618)R 64.318 0.0010351 8252800.0 11397.0 9605.7 13600.0 11091.0 11307.0 10937.0 11765.0 7567.1 12559.0 10260.0 True False 11234.476690046175 9583.458591822446 12481.860497518166 11906.669138491403 10641.944490417305 10469.250005392236 12374.134133412888 7918.695091056703 11144.473167867005 12033.427329409353 0.9336057286513406 0.7964030803095263 1.037265623154 0.9894661606001346 0.8843652102679589 0.8700139801239908 1.028313363655827 0.6580581636707639 0.9261262699970965 1.0 13.55475998523241 TVRGS(ph)LER ddPTM_PC-9_AZD4547_30min_R2 1 TVRGSLER 8 1 Q6NZI2 Q6NZI2 PTRF Polymerase I and transcript release factor 1 T(0.067)VRGS(0.933)LER 62.166000000000004 0.029731999999999998 17230000.0 17884.0 17535.0 28365.0 43342.0 39227.0 34369.0 25272.0 31132.0 21381.0 28968.0 True False 23570.73998969125 23202.84583438575 27988.86156663823 33350.17152722479 33781.008157307544 32219.90099684613 27521.159041648865 26321.264742190757 22511.156009823382 27953.83913717299 0.8432022476063727 0.8300414737498659 1.001252866530904 1.1930444102354356 1.2084568417074988 1.1526109468806427 0.984521621756464 0.9415974890972584 0.8052974727141529 1.0 14.770758813737944 -10.989565464398405 2.890293751568166 0.9998388881739018 1.0056353467769374 0.0 0.141343329942759 98056126.71540497 42535662.536036454 112951.11946572586 0.040986707894087676 1.0243173657895405e-11 10.989565464398405 0.005796458603035681 TVRGS(ph)LER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVRGSLER 8 1 Q6NZI2 Q6NZI2 PTRF Polymerase I and transcript release factor 1 T(0.014)VRGS(0.986)LER 62.166000000000004 0.029731999999999998 18105000.0 29814.0 20223.0 30632.0 38317.0 45455.0 35664.0 36835.0 39251.0 35372.0 22393.0 True False 34860.921346658615 22230.605790849062 31362.383052506924 36170.222715390104 36548.41905144772 33793.71705711619 33345.72213769408 38220.702839872196 35889.24858275049 26452.673637109532 1.3178600327852472 0.8403916403997258 1.1856035228329334 1.367356026524599 1.3816531195612387 1.2775161225936786 1.2605804084360883 1.4448710691479483 1.3567342596478686 1.0 14.691125926012075 -5.529405640868144 7.68672222665635 1.315229104678157 1.0625511590794277 0.23728180799808862 0.15620711957611497 0.13436426228585166 57.06043770070807 0.03932630090822806 0.07160500469845853 2.95525090588991e-06 5.529405640868144 -0.25267794559872936 TVS(ph)ASESEDR ddPTM_PC-9_Lapatinib_30min_R1 1 TVSASESEDR 10 0 H3BNE2;Q9ULG6-3;Q9ULG6-4;Q9ULG6-2;Q9ULG6;Q9ULG6-5 H3BNE2 CCPG1 Cell cycle progression protein 1 1 T(0.009)VS(0.979)AS(0.01)ES(0.002)EDR 82.171 0.038417 0.0 16917.0 17295.0 16817.0 11108.0 16082.0 18615.0 18886.0 13839.0 22755.0 12780.0 True False 16675.76047780215 17254.954490101638 15434.371175497272 11924.919375201738 15136.088378428514 17818.87984368442 19863.824670092294 14482.010461753353 20192.092279227145 14989.005971720419 1.1125327796429003 1.1511740353333875 1.0297127911361914 0.7955777319523618 1.0098126858435839 1.18879663383303 1.3252262830216452 0.9661755081742173 1.3471268419882765 1.0 13.87161709057235 -6.759208482882426 24.921322040610555 1.1733361127515733 1.0151607914067036 0.20604099289630406 0.14244710940767744 90.17132420568478 1007305.1225402029 0.04881308353967311 0.04657218540171836 1.74097092040394e-07 6.759208482882426 -0.15817532134486978 TVS(ph)ASSTGDLPK ddPTM_PC-9_AZD4547_30min_R2 1 TVSASSTGDLPK 12 0 P78362;P78362-2;H7C5L6 P78362 SRPK2 SRSF protein kinase 2;SRSF protein kinase 2 N-terminal;SRSF protein kinase 2 C-terminal 1 T(0.003)VS(0.848)AS(0.137)S(0.01)T(0.002)GDLPK 71.888 0.026333999999999996 12813000.0 59018.0 63879.0 85038.0 114090.0 75626.0 70934.0 58808.0 69928.0 60340.0 61002.0 True False 77784.49634934023 84526.63752807122 83910.34055715785 87788.31317292884 65126.63529978174 66498.48576654204 64041.79807380845 59122.23438558129 63529.44921344852 58866.338547563704 1.3213748004131556 1.4359078484178887 1.4254384190951288 1.4913160107961587 1.1063476497210667 1.1296521476838857 1.0879188285519577 1.0043470656461981 1.0792152320144228 1.0 15.845155275188072 -6.31937636468901 5.726179145300475 1.069563708618336 1.4200433723596486 0.9100730686616032 0.05402454752047455 0.06116349614264989 4.324619760046671 0.017440425149575885 0.01998375450480409 4.79317886098144e-07 6.31937636468901 0.35047966374131256 TVS(ph)DNSLSNSR ddPTM_PC-9_AZD4547_30min_R2 2 TVSDNSLSNSR 11 0 H0Y7W6;B7ZL14;Q96RU3-4;Q96RU3-3;Q96RU3-5;Q96RU3-2;Q96RU3 H0Y7W6;Q96RU3-5 FNBP1 Formin-binding protein 1 1 T(0.022)VS(0.875)DNS(0.05)LS(0.054)NSR;T(0.258)VS(0.739)DNS(0.002)LSNSR 119.21 0.0009872 39554000.0 34096.0 34640.0 49225.0 65909.0 61731.0 49902.0 38274.0 61023.0 48161.0 45164.0 True False 44937.81875914298 45836.70257787982 48572.24433695636 50714.69833389922 53160.71620462314 46781.62005134328 41680.31185343734 51593.29751903847 50706.69213736984 43582.822106851694 1.031090154028329 1.0517148812782775 1.114481394019693 1.1636396149281558 1.2197630542209816 1.0733958424410681 0.9563472450510437 1.1837989149153203 1.1634559141914356 1.0 15.411471997475012 -10.631049609502197 4.244563819648592 0.9999871185936499 1.1069471173731587 0.1500532118943133 0.07596615794815038 1.3478605545456887e-05 2.832026321897188e-06 0.07868153566353843 0.01907994862455356 2.3385700883057576e-11 10.631049609502197 0.10695999877950879 TVS(ph)DNSLSNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TVSDNSLSNSR 11 0 H0Y7W6;B7ZL14;Q96RU3-4;Q96RU3-3;Q96RU3-5;Q96RU3-2;Q96RU3 H0Y7W6;Q96RU3-5 FNBP1 Formin-binding protein 1 1 T(0.007)VS(0.992)DNS(0.001)LSNSR;T(0.067)VS(0.904)DNS(0.022)LS(0.006)NSR;T(0.222)VS(0.777)DNS(0.001)LSNSR 104.59 0.0026634000000000002 90967000.0 36024.9 48855.0 36323.8 55063.0 72419.0 42773.0 55573.0 53474.0 36590.6 39570.0 True False 42123.20404579198 53705.00152855316 37189.89715077863 51977.99862665464 58229.01681414133 40529.90858243693 50308.72312632208 52070.36416038633 37125.66830238579 46743.72776405236 0.9011520060705613 1.1489242321373923 0.7956125651446015 1.1119780366902536 1.2457075975639575 0.8670662465565255 1.0762668176629964 1.1139540351428785 0.7942385016827176 1.0 15.512485171698861 -10.567283975270142 9.619705498916227 1.0000030372860547 1.015417923856004 0.0 0.15029728184780264 0.0 2.1593525326952853e-10 0.13940078242753562 0.03380965539281462 2.708420078562902e-11 10.567283975270142 0.015414886569949271 TVS(ph)DNSLSNSR ddPTM_PC-9_Lapatinib_30min_R1 1 TVSDNSLSNSR 11 0 H0Y7W6;B7ZL14;Q96RU3-4;Q96RU3-3;Q96RU3-5;Q96RU3-2;Q96RU3 H0Y7W6;Q96RU3-5 FNBP1 Formin-binding protein 1 1 T(0.001)VS(0.8)DNS(0.18)LS(0.019)NSR 77.74 0.019166 85542000.0 13500.0 11456.0 14412.0 16778.0 15648.0 15329.0 12661.0 13623.0 15466.0 13019.0 True False 13307.487524403201 11429.474335854542 13227.100991928812 18011.910089767258 14727.615405151673 14673.414403644301 13316.524629251222 14255.974313206583 13724.056215799908 15269.316803272943 0.8715182018851538 0.7485255878249026 0.866253622368593 1.1796146691976714 0.9645235340192067 0.9609738662635573 0.8721100492457433 0.9336353745801416 0.8987996249352943 1.0 13.89834789246482 -5.533226246023272 24.999860522383234 0.9694647139099696 0.8093637683376702 0.39960936794877644 0.08277173555209337 200.97808419719544 485567.245248394 0.023397782877714993 0.04057975283025239 2.929366791940394e-06 5.533226246023272 -0.16010094557229937 TVS(ph)EPNLK ddPTM_PC-9_AZD4547_30min_R2 1 TVSEPNLK 8 0 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;F8VWY3;H0YI41;C9JEB6;C9JAH2;C9JF80 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 T(0.31)VS(0.69)EPNLK 68.626 0.043082999999999996 61436000.0 68129.0 57566.0 78353.0 83814.0 63570.0 90451.0 75447.0 74158.0 71497.0 66702.0 True False 89792.60482876725 76173.0837355148 77313.98802505931 64491.9772133917 54744.40279807374 84795.08467123662 82161.63683979439 62698.58508131125 75276.18545598161 64366.783282508644 1.3950146372029117 1.1834222536985852 1.2011473011743468 1.0019450083490047 0.8505070473663123 1.3173733461103263 1.276460196545528 0.9740829335237151 1.1694880747044811 1.0 15.974028751794139 -4.6402225798154095 1.4288814425684955 1.0970543749586479 1.589143720092056 0.3044261677393494 0.1374245205269782 2.312890476647281 3.3778614246553387 0.04153106152639511 1.7964997193869612 2.289693863372672e-05 4.6402225798154095 0.4920893451334081 TVS(ph)EPNLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVSEPNLK 8 0 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;F8VWY3;H0YI41;C9JEB6;C9JAH2;C9JF80 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 T(0.009)VS(0.991)EPNLK 90.82700000000001 0.0091832 47304000.0 340500.0 346710.0 301960.0 398380.0 407540.0 348080.0 380200.0 333930.0 295850.0 249130.0 True False 398139.9248184489 381129.0774734342 309159.87158967723 376060.0601653863 327685.46255036874 329826.0720401806 344184.70359037 325164.69132808055 300176.24655678833 294295.2968880045 1.352858605042414 1.2950566370025094 1.0505090460461197 1.2778323817675474 1.1134580335311 1.1207317124258955 1.1695215901508311 1.1048925849869204 1.0199831588576893 1.0 18.166904961293547 -1.5228787452803376 0.20379090510242812 1.0142941238355359 2.5358005444328504 0.628653486578594 0.07012988599263642 36.744370379365925 0.44917198137810016 0.1262053432467675 17.952496194288226 0.029999999999999995 1.5228787452803376 1.5215064205973146 TVS(ph)EPNLK ddPTM_PC-9_Lapatinib_30min_R1 2 TVSEPNLK 8 0 Q8WUI4-8;Q8WUI4-5;Q8WUI4-6;Q8WUI4-7;Q8WUI4;Q8WUI4-4;Q8WUI4-3;J3KPH8;F8VWY3;H0YI41;C9JEB6;C9JAH2;C9JF80 Q8WUI4-8 HDAC7 Histone deacetylase 7;Histone deacetylase 1 T(0.047)VS(0.953)EPNLK;T(0.239)VS(0.761)EPNLK 101.38 0.0046034 103049000.0 678640.0 655380.0 638040.0 538420.0 605190.0 597050.0 587700.0 609690.0 575940.0 527590.0 True False 668962.4691526645 653862.5078764288 585582.814105625 578017.2029164674 569593.9140493195 571515.5632915273 618128.2303618154 638018.4231827742 511071.5722829307 618783.2285305136 1.0810934076886936 1.0566907403570414 0.9463456459482057 0.9341190521422869 0.9205063870298992 0.9236119159996667 0.9989414739467751 1.0310855139011126 0.8259299035893773 1.0 19.239074569019884 -5.217795800654102 4.213732877804109 0.9478631696913496 1.0744774094866218 0.45194864113566924 0.05363872419524444 0.1896457968890631 7.45645830057574 0.013769527388304063 0.03863087141393874 6.056255647057672e-06 5.217795800654102 0.1266142397952722 TVS(ph)FEALPIMR ddPTM_PC-9_AZD4547_30min_R2 4 TVSFEALPIMR 11 0 O15084-2;O15084;O15084-4;O15084-1 O15084-2 ANKRD28 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A 1 T(0.001)VS(0.999)FEALPIMR;T(0.176)VS(0.824)FEALPIMR;T(0.027)VS(0.973)FEALPIMR;T(0.092)VS(0.908)FEALPIMR 108.98 0.0018644000000000002 25178600.0 113428.5 120318.0 176758.6 240580.0 234814.0 196022.8 175481.6 226460.0 179528.8 185234.5 True False 149496.40354063374 159208.44055327203 174414.66547198256 185117.99792394787 202214.12928467637 183765.46332813188 191099.1224470956 191465.81053310155 189018.32585269056 178749.4965359934 0.8363458719478452 0.8906790991784049 0.97574912854013 1.0356280801421562 1.131271042455541 1.0280614317206116 1.069089010880741 1.0711404185384519 1.057448157984766 1.0 17.44757965285344 -5.363763518209806 1.597352163824549 1.0631830389669954 0.8362196909501969 0.8498059426273735 0.032617455431879855 0.15559010999496514 0.6994852641379949 0.00951118163835288 0.03832600668265432 4.327494073583039e-06 5.363763518209806 -0.22696334801679852 TVS(ph)FEALPIMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVSFEALPIMR 11 0 O15084-2;O15084;O15084-4;O15084-1 O15084-2 ANKRD28 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A 1 T(0.033)VS(0.967)FEALPIMR;T(0.001)VS(0.999)FEALPIMR 96.604 0.0050508 12227000.0 71415.0 72881.0 92553.0 106138.0 118024.0 110261.0 99160.0 101344.0 86444.0 78664.0 True False 83504.14898945553 80116.14402625064 94759.81452920717 100191.43196403861 94898.04444237301 104478.71905660287 89766.84694376928 98683.8273828439 87708.07996401898 92925.16049611868 0.8986172156564997 0.8621577148591199 1.0197433507060245 1.0781948767064375 1.0212308909204062 1.1243318655442813 0.96601228843203 1.061971019000454 0.9438571802916863 1.0 16.503781654396015 -5.290108949385174 6.890547059383431 1.0323805452514223 0.8802082127299237 0.5710289177558807 0.050641031196269046 0.113479840331454 20.762638343169954 0.012671042181859847 0.027603643823157623 5.127327410389096e-06 5.290108949385174 -0.15217233252149864 TVS(ph)FEALPIMR ddPTM_PC-9_Lapatinib_30min_R1 4 TVSFEALPIMR 11 0 O15084-2;O15084;O15084-4;O15084-1 O15084-2 ANKRD28 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A 1 T(0.002)VS(0.998)FEALPIMR;T(0.257)VS(0.743)FEALPIMR;TVS(1)FEALPIMR;T(0.262)VS(0.738)FEALPIMR 126.66 0.00035187 20145300.0 157600.6 121787.6 145706.7 132963.2 130513.9 124015.2 118740.3 110110.0 144146.4 135557.2 True False 155353.18654358957 121505.6082948078 133727.25757012726 142741.75728023224 122837.32900220007 118711.35898955105 124888.09173325011 115226.11257631768 127911.11450311507 158988.0814013849 0.9771373122704803 0.7642435031846947 0.8411149841636015 0.8978142010523618 0.772619732997986 0.7466682907497303 0.7855185787037383 0.7247468587624203 0.8045327258223073 1.0 17.27855909184826 -6.272634765237693 24.341004839739963 0.7879596115307261 0.8604491786087525 0.09216641516824597 0.08707439452073862 1007.5353465973924 2190578.2979302066 0.02545392512481976 0.02914755129868351 5.337836103194823e-07 6.272634765237693 0.07248956707802634 TVS(ph)PPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVSPPIR 7 0 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 T(0.019)VS(0.981)PPIR 82.279 0.022713 50474000.0 17156.0 15233.0 10780.0 17389.0 21234.0 14610.0 14134.0 15051.0 15478.0 10513.0 True False 20060.17195355454 16745.23156861017 11037.03608337766 16414.750705898634 17073.35012954442 13843.825880564924 12795.125198701458 14655.92719785269 15704.336468500844 12418.923679137793 1.6152907024666776 1.3483641578971952 0.8887272656259633 1.3217530866602651 1.3747850112184414 1.1147363683231892 1.0302926025864572 1.180128614726313 1.2645489153687388 1.0 13.600252523312564 -4.929111942428565 4.083165750784104 1.159636150136854 1.5992000947809117 0.5072190743273225 0.14308291932074826 0.18658962877043567 5.849611166398927 0.03678795591135308 0.1812965799378938 1.1773024764923297e-05 4.929111942428565 0.4395639446440578 TVS(ph)PPIR ddPTM_PC-9_Lapatinib_30min_R1 1 TVSPPIR 7 0 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 T(0.001)VS(0.999)PPIR 69.598 0.046141 161090000.0 25331.0 28906.0 34095.0 20282.0 27435.0 27445.0 24449.0 27596.0 27242.0 26040.0 True False 24969.775294863524 28839.069932979342 31291.840710506014 21773.60593876861 25821.327239285296 26271.24132741977 25714.84959012424 28878.210904150987 24173.71908902245 30540.979303881046 0.8175826664369746 0.9442745645459565 1.0245853742656363 0.7129308370279304 0.8454649401502331 0.8601964287399687 0.841978553937741 0.9455561531545663 0.7915174837222896 1.0 14.898458702790991 -10.288313186202451 11.792201485960474 0.9999999997515115 0.86844846640488 0.18886871170919384 0.08370326166414045 0.0 0.0 0.08142567101900809 0.01974862586745923 5.148572276262371e-11 10.288313186202451 -0.1315515333466315 TVS(ph)PPTVCTIPTVVGR ddPTM_PC-9_AZD4547_30min_R2 1 TVSPPTVCTIPTVVGR 16 0 A0A0C4DH56;Q9BWT3-2;Q9BWT3 A0A0C4DH56 PAPOLG Poly(A) polymerase gamma 1 T(0.248)VS(0.598)PPT(0.121)VCT(0.033)IPT(0.001)VVGR 85.28 0.004767 9685500.0 3690.5 10292.0 17341.0 15704.0 19885.0 17794.0 11892.0 17513.0 12704.0 14603.0 True False 4864.002232831336 13618.687728970524 17111.047009591894 12083.685424381392 17124.3109900849 16681.33836707149 12950.364962143409 14806.768258704433 13375.507504269966 14091.753414807275 0.34516657293480313 0.9664296080188527 1.214259610277598 0.8575004876032067 1.2152008686222886 1.183765985398463 0.9190030921585299 1.0507399485961653 0.9491726906188483 1.0 13.782563514650569 -4.769109794413651 4.248604609755552 1.0522487620512782 0.28244387120677394 0.7591447045895121 0.11809330630809797 0.09927286853987484 3.647901482207262 0.028918744393855864 0.23574822548118055 1.7017282384248234e-05 4.769109794413651 -0.7698048908445042 down TVS(ph)SPIPYTPSPSSSR ddPTM_PC-9_AZD4547_30min_R2 3 TVSSPIPYTPSPSSSR 16 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 T(0.103)VS(0.449)S(0.449)PIPYTPSPSSSR;T(0.218)VS(0.391)S(0.391)PIPYTPSPSSSR;TVS(0.959)S(0.04)PIPYTPSPSSSR 203.85 7.4821e-17 34308000.0 51380.0 62149.4 77397.0 85547.0 78672.0 84149.0 64566.0 84570.0 73854.0 71554.0 True False 67717.77122960951 82237.97815224246 76370.6652096986 65825.46083797474 67749.75077756894 78887.14972747542 70312.24891908448 71501.64972526875 77757.77166407063 69048.91623934248 0.9807217103144842 1.191010411621568 1.1060371309084265 0.9533163505391691 0.9811848536873443 1.1424820840638676 1.018296198529213 1.0355216796947895 1.1261258814626558 1.0 16.075331150319577 -8.739109432658237 0.00540217095144667 6.721799467155785e-07 2.087587371162885 0.01770468267157277 0.07667442379088082 32814.61759393978 94.76495590801265 18488.647270821057 18124.980145761096 1.8234361786119653e-09 8.739109432658237 2.087586698982938 TVS(ph)SPIPYTPSPSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVSSPIPYTPSPSSSR 16 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 TVS(0.5)S(0.5)PIPYTPSPSSSR 214.58 6.005399999999999e-22 18853000.0 46199.0 66680.0 52655.0 44255.0 58182.0 38926.0 50589.0 41688.0 30041.0 29536.0 True False 54019.57822815729 73299.54972723221 53910.49489519954 41775.53582664585 46781.65476298169 36884.652034693376 45796.843687357316 40593.73417208713 30480.292793011635 34890.64299315264 1.548254018670815 2.1008368845944565 1.545127583512278 1.1973277716562685 1.3408080433531329 1.057150252058469 1.3125823934040148 1.163456178782768 0.8735950437770221 1.0 15.090552564484572 -5.628772025368467 2.9476870344955346 1.1496193952329008 1.8300881366151172 0.7048810858034077 0.18204320404893803 0.13087313416859317 2.2691400551495784 0.04977516835725303 0.09710061905262792 2.350866539707042e-06 5.628772025368467 0.6804687413822164 TVS(ph)SPIPYTPSPSSSR ddPTM_PC-9_Lapatinib_30min_R1 1 TVSSPIPYTPSPSSSR 16 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 T(0.004)VS(0.964)S(0.032)PIPYTPSPSSSR 91.65700000000001 0.018308 0.0 4721.4 3805.2 4247.2 6032.8 7714.2 6151.4 6071.9 6387.4 5865.8 5019.3 True False 4654.071970201283 3796.3892931907903 3898.011610666112 6476.472236830844 7260.465922700734 5888.3189616137715 6386.273271965126 6684.18192235012 5205.131834387632 5886.879317203154 0.7905838933372978 0.6448899473948191 0.6621524581411073 1.100153729651758 1.2333301791126523 1.000244551371456 1.0848316956834156 1.1354372261067114 0.8841920402846956 1.0 12.523287336933581 -5.761910796995334 24.99999999998205 1.073683860657066 0.6937768182539065 0.7551301884217096 0.09466616646217935 5.578706882762462 295878.27894333744 0.02607773137862143 0.04151532024659393 1.7301716956773184e-06 5.761910796995334 -0.37990704240315953 TVS(ph)SPPTSPRPGSAATVSASTSNIIPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVSSPPTSPRPGSAATVSASTSNIIPPR 28 1 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 1 T(0.083)VS(0.245)S(0.216)PPT(0.215)S(0.215)PRPGS(0.001)AAT(0.001)VS(0.001)AS(0.002)T(0.014)S(0.006)NIIPPR 52.532 0.004165100000000001 73752000.0 18764.0 17087.0 20977.0 24002.0 23988.0 22318.0 23322.0 19421.0 18726.0 21996.0 True False 21940.37459410687 18783.284435951045 21477.171235715512 22657.24575553392 19287.723599298824 21147.60479140642 21112.77132334197 18911.219328250423 18999.83232388855 25983.700679759815 0.8443899067540244 0.7228871925307551 0.8265632174729177 0.8719791701257912 0.7423008691877032 0.8138796336997328 0.812539044516777 0.7278108519384788 0.731221182003863 1.0 14.66531929809984 -6.28787869103354 24.891430050632852 0.7918742282938417 0.8104935370051808 0.0 0.08205522009243206 5153.317047716657 4851599.877418207 0.02453057772061094 0.02782437913548663 5.153725805213626e-07 6.28787869103354 0.0186193087113391 TVS(ph)SSGCEGK ddPTM_PC-9_AZD4547_30min_R2 2 TVSSSGCEGK 10 0 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 T(0.321)VS(0.37)S(0.303)S(0.007)GCEGK;T(0.022)VS(0.96)S(0.017)SGCEGK 107.97 0.0020959 15951800.0 55739.0 52001.0 40688.0 60920.0 48108.0 54665.0 43585.0 42483.0 88689.0 68273.0 True False 73462.84255677709 68809.30631502088 40148.4505349331 46875.83520461756 41429.034604526234 51246.78890839401 47463.980564667036 35918.22851222182 93376.91947781792 65882.78305068387 1.1150537235238205 1.0444201524104655 0.6093921458060865 0.7115035679132712 0.628829455681232 0.7778479677910641 0.720430715990744 0.5451838378562393 1.4173189891808717 1.0 16.00761387888535 -10.271447266893277 5.725022830076706 1.0000000125920812 0.816104397408323 0.02467439137965788 0.25994536320335526 83914084.28371029 150552971.4213504 8.456524996319953 0.06228294777338115 5.3524514061036696e-11 10.271447266893277 -0.1838956151837582 TVS(ph)SSGCEGKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVSSSGCEGKR 11 1 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 T(0.023)VS(0.927)S(0.043)S(0.007)GCEGKR;T(0.002)VS(0.989)S(0.009)S(0.001)GCEGKR 105.25 0.0037922 11347200.0 15620.8 17577.4 14661.8 14651.1 20115.9 19174.0 20799.9 21068.7 19799.3 18790.1 True False 18265.092915136673 19322.368107010356 15011.392917186147 13830.246366507088 16174.333798196401 18168.481686102106 18829.582893764706 20515.668949132883 20088.82730590444 22196.596387650246 0.8228780933863813 0.870510404818684 0.6762925565262877 0.6230795985551175 0.7286853135373261 0.8185255689115785 0.848309468934666 0.9242709373472864 0.9050408880291878 1.0 14.438050851119616 -7.466540014708798 1.3119918526289072 0.95166777490929 0.7433341628085126 0.606286169304434 0.0691934663682365 0.3618188587703208 1.1848859547667612 0.055773373474014544 0.027131774476973115 3.415544793382773e-08 7.466540014708798 -0.2083336121007774 TVS(ph)TSSTSGNDFEETK ddPTM_PC-9_AZD4547_30min_R2 1 TVSTSSTSGNDFEETK 16 0 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 TVS(0.332)T(0.332)S(0.332)S(0.002)TSGNDFEETK 268.93 2.9743999999999997e-69 13853000.0 37762.0 41285.0 40910.0 50950.0 43841.0 38550.0 38074.0 45913.0 38017.0 36513.0 True False 49769.53050160599 54629.5688778224 40367.50666988086 39204.264669653094 37754.43390074488 36139.462405901206 41462.51224088867 38818.200825780696 40026.50100675626 35234.69098369226 1.4125150274381835 1.550448360767708 1.1456750589515383 1.1126609479219807 1.07151312660068 1.0256784264867742 1.1767525436814203 1.1017040235643616 1.1359969362376927 1.0 15.104708940910351 -5.32805903255286 5.153052548301064 1.0970062801157094 1.4811454256596932 0.8748447595934249 0.05841217001508285 0.058863444393208265 3.05353276784803 0.014932529053747281 0.03268456330146092 4.698302414256946e-06 5.32805903255286 0.38413914554398376 TVS(ph)TSSTSGNDFEETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVSTSSTSGNDFEETK 16 0 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 TVS(0.768)T(0.063)S(0.167)S(0.001)TSGNDFEETK;T(0.107)VS(0.868)T(0.019)S(0.002)S(0.001)T(0.001)S(0.002)GNDFEETK 203.06 8.1309e-17 14272200.0 10886.3 12815.6 12030.2 17925.8 44322.0 46541.0 64316.0 62701.0 53808.0 53064.0 True False 12729.135575774126 14087.84807265021 12317.045592787563 16921.475542227727 35637.42226813917 44100.30802925204 58223.5228724836 61055.16518720098 54594.84020526515 62684.08314560714 0.20306806667660698 0.22474362494743574 0.19649398977690452 0.2699485211089599 0.5685242645307259 0.7035327919978129 0.9288406234998727 0.9740138504598944 0.8709522013498753 1.0 15.93581153737618 -6.631174993792183 1.1970724796430434 0.9543943611210531 0.1928044373970808 0.9823177737973188 0.04335280078468723 0.053303719135735284 0.1613646132652747 0.0206325757123907 0.021068528754152174 2.3378950218729047e-07 6.631174993792183 -0.7615899237239723 down TVS(ph)TSSTSGNDFEETK ddPTM_PC-9_Lapatinib_30min_R1 1 TVSTSSTSGNDFEETK 16 0 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 T(0.007)VS(0.493)T(0.493)S(0.007)STSGNDFEETK 281.49 3.3108e-83 9867300.0 19296.0 24785.0 21793.0 18302.0 62843.0 83454.0 89182.0 77401.0 93486.0 83308.0 True False 19020.83550154697 24727.61185528586 20001.263663412756 19647.990133682215 59146.69829409173 79884.86696077578 93799.40758912265 80997.33302624252 82956.62222877725 97707.67679906763 0.19467083984263228 0.25307747216359794 0.20470514005306506 0.20108952313017953 0.605343410382429 0.8175904860071146 0.9600003875029984 0.8289761427120067 0.8490287042580554 1.0 16.576184297371015 -6.492410888222489 2.1244560546206905 0.8926883114584658 0.20824067772730145 0.9712354704285788 0.05497595311903101 0.048660546030275975 0.43909004183680567 0.019989872958348195 0.022016271514035974 3.218022762844194e-07 6.492410888222489 -0.6844476337311644 down TVS(ph)VPSEGQFPEYPPEGATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVSVPSEGQFPEYPPEGATK 20 0 Q9UJF2-2 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 T(0.21)VS(0.773)VPS(0.017)EGQFPEYPPEGATK 80.835 0.00077109 7702400.0 26280.0 34336.0 40707.0 45358.0 35030.0 54580.0 42774.0 39999.0 41784.0 36136.0 True False 30728.684946340247 37744.65116128137 41677.60926215721 42816.73831262008 28166.122964959046 51717.72871740132 38722.137063057584 38949.0686324437 42395.01195243824 42687.17074758138 0.7198576154893401 0.8842153391817364 0.9763497681447681 1.003035281157537 0.659826417906952 1.2115520380401785 0.9071141606463002 0.9124303145494954 0.9931558173093564 1.0 15.381514925276313 -6.758199355415697 24.99999974990521 0.9932688178288331 0.8663030292294267 0.272532631721048 0.1252422402886937 146.2261331959149 1128279.8489840373 0.042606570856825135 0.04093057701110806 1.7450209471786255e-07 6.758199355415697 -0.12696578859940644 TVSAS(ph)STGDLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVSASSTGDLPK 12 0 P78362;P78362-2;H7C5L6 P78362 SRPK2 SRSF protein kinase 2;SRSF protein kinase 2 N-terminal;SRSF protein kinase 2 C-terminal 1 TVSAS(0.963)S(0.037)TGDLPK 218.02 5.7707e-11 12894000.0 127060.0 117260.0 100420.0 144590.0 154400.0 125530.0 127590.0 127280.0 120930.0 97289.0 True False 148568.74845060837 128900.79785565719 102814.39364497073 136489.09106710504 124146.42836967396 118946.98581706463 115503.75152839371 123939.03486430732 122698.37247291664 114926.72556069997 1.292725845322548 1.1215911462436703 0.8946082222682663 1.1876183751099447 1.0802224440311274 1.0349810736950067 1.0050208162190175 1.0784178724281794 1.0676226254102401 1.0 16.810354802015723 -4.8400036541941835 3.844797296344031 1.0489342479291075 1.3026076975778258 0.5280011010084427 0.07106606583041279 0.17588925185498902 4.399206633139527 0.01749186180148583 0.11049507608160222 1.4454276087323589e-05 4.8400036541941835 0.2536734496487183 TVSASS(ph)TGDLPK ddPTM_PC-9_AZD4547_30min_R2 1 TVSASSTGDLPK 12 0 P78362;P78362-2;H7C5L6 P78362 SRPK2 SRSF protein kinase 2;SRSF protein kinase 2 N-terminal;SRSF protein kinase 2 C-terminal 1 TVSAS(0.029)S(0.96)T(0.011)GDLPK 179.67 0.00077594 21281000.0 123620.0 101770.0 160900.0 201040.0 181510.0 165090.0 168690.0 178500.0 144560.0 173310.0 True False 162928.58854426473 134665.16227918083 158766.36086980766 154693.33403703745 156310.46959066155 154766.896202081 183703.08320416845 150916.9265219407 152201.14647491073 167242.46965145838 0.9742058275258432 0.8052091227774245 0.9493184428613417 0.9249644205770583 0.9346338278573639 0.9254042739539957 1.098423645542994 0.9023839867735695 0.9100627776670931 1.0 17.35158172721041 -6.208453006239999 1.17799837858242 0.9678990412902059 0.897302269862992 0.1329138710041694 0.06639611701276259 0.9519913354054462 2.7142408649680134 0.027324587606988276 0.04241081976361919 6.187952819929856e-07 6.208453006239999 -0.07059677142721388 TVSASS(ph)TGDLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TVSASSTGDLPK 12 0 P78362;P78362-2;H7C5L6 P78362 SRPK2 SRSF protein kinase 2;SRSF protein kinase 2 N-terminal;SRSF protein kinase 2 C-terminal 1 TVSAS(0.002)S(0.949)T(0.048)GDLPK;TVSAS(0.046)S(0.88)T(0.074)GDLPK;TVSAS(0.002)S(0.991)T(0.007)GDLPK 195.72 1.3725999999999999e-05 40290000.0 304400.0 300052.0 287312.0 365152.0 355810.0 330457.0 317198.0 291443.0 282308.0 263373.0 True False 355928.90782595007 329839.1795854143 294162.60771682754 344693.7172787566 286091.5847034559 313127.25318369863 287150.709125351 283792.9300593841 286436.2204257353 311120.4400404791 1.1440228992336248 1.0601655729932105 0.945494316215787 1.1079108696102042 0.9195525201308961 1.0064502774004769 0.9229567465512407 0.9121642088911307 0.9206602445935977 1.0 18.247113654832525 -1.5228787455669908 0.39812464922022006 0.9377770178539916 4.18212062743295 0.5320637505504098 0.05518009072419301 54.749955767974996 0.728386630447664 0.0390476255942639 139.11613574969803 0.0299999999801987 1.5228787455669908 3.2443436095789586 TVSASS(ph)TGDLPK ddPTM_PC-9_Lapatinib_30min_R1 3 TVSASSTGDLPK 12 0 P78362;P78362-2;H7C5L6 P78362 SRPK2 SRSF protein kinase 2;SRSF protein kinase 2 N-terminal;SRSF protein kinase 2 C-terminal 1 TVSAS(0.111)S(0.864)T(0.025)GDLPK;TVSAS(0.002)S(0.951)T(0.047)GDLPK;TVSAS(0.147)S(0.843)T(0.01)GDLPK 214.0 1.0581999999999999e-10 55654000.0 534820.0 428990.0 470310.0 425260.0 461760.0 429680.0 346206.0 352737.0 407480.0 318804.0 True False 527193.3687260231 427996.7000120676 431642.9272491002 456535.03902577434 434600.18465508916 411303.58803300187 364130.8526810323 369126.44874972885 361585.31144537334 373908.8466203721 1.4099515790844075 1.144655185028587 1.154406832442093 1.2209795065086873 1.1623158654396233 1.1000103146813118 0.9738492575724818 0.987209722599854 0.967041338319789 1.0 18.512327079958524 -6.8632929489826076 1.0531468096963814 0.9679957751703039 1.2337742548401114 0.7305582680001441 0.06855110376703291 0.2778286197001437 0.650721922928308 0.04008281790858527 0.03282028838906854 1.3699573634409857e-07 6.8632929489826076 0.2657784796698075 TVSDNS(ph)LSNSR ddPTM_PC-9_AZD4547_30min_R2 3 TVSDNSLSNSR 11 0 H0Y7W6;B7ZL14;Q96RU3-4;Q96RU3-3;Q96RU3-5;Q96RU3-2;Q96RU3 H0Y7W6;Q96RU3-5 FNBP1 Formin-binding protein 1 1 T(0.014)VS(0.035)DNS(0.937)LS(0.013)NSR;T(0.133)VS(0.366)DNS(0.5)LSNSR;T(0.001)VS(0.002)DNS(0.967)LS(0.031)NSR 120.6 0.00085019 74649600.0 28966.6 27212.2 45167.0 53331.0 46842.0 43826.0 33258.3 45934.0 44022.0 42180.0 True False 38177.37625729092 36008.01148642552 44568.056068406455 41036.36190573639 40338.796851775536 41085.55329185544 36218.22427013577 38835.95575831268 46348.91304730581 40703.291038592804 0.937943229727863 0.8846461936526102 1.0949496940222665 1.008182897712811 0.9910450929761018 1.0093914335550949 0.8898107093059251 0.9541232359194344 1.138701855910376 1.0 15.31285782694282 -5.23157271887033 24.891659843712482 1.0039703065216454 0.9112946927363733 0.26182759076693296 0.06602820528395051 979.7099486779504 816512.7579007904 0.017110417069818428 0.04526017152259446 5.86715121000042e-06 5.23157271887033 -0.09267561378527212 TVSDNS(ph)LSNSR ddPTM_PC-9_Lapatinib_30min_R1 1 TVSDNSLSNSR 11 0 H0Y7W6;B7ZL14;Q96RU3-4;Q96RU3-3;Q96RU3-5;Q96RU3-2;Q96RU3 H0Y7W6;Q96RU3-5 FNBP1 Formin-binding protein 1 1 T(0.046)VS(0.098)DNS(0.855)LSNSR 133.88 5.6067e-05 28086000.0 16359.0 16653.0 22200.0 17080.0 24316.0 13455.0 19211.0 18317.0 24975.0 15363.0 True False 16125.71766012681 16614.441001657277 20374.801694478178 18336.12017720972 22885.780687095346 12879.561015136936 20205.65157985507 19168.07468949606 22162.052501590755 18018.474080089254 0.8949546775409813 0.9220781364619849 1.1307728725482202 1.0176289121769457 1.2701286793416406 0.7147975437814176 1.1213852788002003 1.063801218921037 1.2299627817030427 1.0 14.137189219208043 -5.168638178014215 6.216530909932389 1.0652657720176744 0.9035712881696079 0.1660009568862294 0.14357174289776764 0.42032373876540335 23.101908421831336 0.035657556661248306 0.09729802253349941 6.782063035492857e-06 5.168638178014215 -0.1616944838480665 TVSDNSLS(ph)NSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVSDNSLSNSR 11 0 H0Y7W6;B7ZL14;Q96RU3-4;Q96RU3-3;Q96RU3-5;Q96RU3-2;Q96RU3 H0Y7W6;Q96RU3-5 FNBP1 Formin-binding protein 1 1 TVS(0.001)DNS(0.046)LS(0.878)NS(0.075)R 83.87700000000001 0.036495 0.0 17359.0 16173.0 16372.0 11814.0 19126.0 14338.0 14244.0 13697.0 13789.0 10834.0 True False 20297.535844121776 17778.548556366597 16762.370571155767 11152.099881504784 15378.397597139798 13586.090039393546 12894.705202370415 13337.468263171113 13990.638038774925 12798.118438103196 1.5859781218847717 1.3891533073670748 1.3097527306240582 0.8713858943750822 1.2016139459496222 1.0615693318593116 1.0075469503376102 1.0421428999642743 1.093179290880861 1.0 13.643644102309851 -5.3878204252634525 2.110999294426754 1.0483211084215271 1.5263234561716394 0.7876990252074259 0.09422181851346143 0.14168274765717512 1.1924365185373516 0.02549694903979356 0.07767365525404805 4.094299183193996e-06 5.3878204252634525 0.4780023477501123 TVSDNSLS(ph)NSR ddPTM_PC-9_Lapatinib_30min_R1 1 TVSDNSLSNSR 11 0 H0Y7W6;B7ZL14;Q96RU3-4;Q96RU3-3;Q96RU3-5;Q96RU3-2;Q96RU3 H0Y7W6;Q96RU3-5 FNBP1 Formin-binding protein 1 1 TVSDNS(0.483)LS(0.516)NSR 110.8 0.0018913 2686600.0 13038.0 13344.0 13995.0 12822.0 14126.0 12326.0 9804.8 9018.0 12821.0 9529.2 True False 12852.075729123624 13313.10278785291 12844.385122262256 13764.97265293812 13295.136452784549 11798.84571330939 10312.444568745152 9437.00920182756 11376.963968884696 11176.309523139134 1.1499391371109602 1.1911895210391064 1.1492510202647468 1.2316205653073125 1.1895819836824177 1.0557014092068024 0.9227057059751737 0.844376149594768 1.0179535512442754 1.0 13.448156260788341 -6.991362862009285 2.873260463052058 0.9343537130558313 1.1837734604041004 0.832390950965772 0.049792338275030844 0.09799726222411566 1.6460907386195924 0.019797434514359554 0.016057684549904458 1.0200868239402036e-07 6.991362862009285 0.2494197473482691 TVSDNSLSNS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 TVSDNSLSNSR 11 0 H0Y7W6;B7ZL14;Q96RU3-4;Q96RU3-3;Q96RU3-5;Q96RU3-2;Q96RU3 H0Y7W6;Q96RU3-5 FNBP1 Formin-binding protein 1 1 TVSDNS(0.181)LS(0.11)NS(0.708)R 87.831 0.010159 3010600.0 11304.0 10825.0 16177.0 11678.0 10919.0 11286.0 11149.0 11429.0 14991.0 9121.8 True False 11142.802887100288 10799.935377586018 14846.989505025836 12536.839076665992 10276.76588757996 10803.32408895098 11726.240667524029 11960.033063615787 13302.55571777165 10698.49097596552 1.0415303347110287 1.0094821224645976 1.3877648294867044 1.1718324672919178 0.9605808810482733 1.0097988691321953 1.0960649211059186 1.1179177596620269 1.2434048640744044 1.0 13.385119698136492 TVSDS(ph)IKK ddPTM_PC-9_Lapatinib_30min_R1 1 TVSDSIKK 8 1 Q9Y490 Q9Y490 TLN1 Talin-1 1 T(0.093)VS(0.046)DS(0.861)IKK 78.939 0.031464 5429400.0 17641.0 17452.0 16898.0 15956.0 16636.0 16958.0 17459.0 13863.0 15769.0 12905.0 True False 17389.4361050368 17411.590966247673 15508.711668166323 17129.45746765564 15657.503187634407 16232.745871028763 18362.941592456908 14507.125589369656 13992.929165068454 15135.612055168394 1.148908682493536 1.1503724396993973 1.0246504476751916 1.1317320637724988 1.0344810061571181 1.0724869144281304 1.2132275540311876 0.9584763098110639 0.9245036879952439 1.0 13.885659395719326 -7.800510226605685 21.019281929648727 0.9561150189351657 1.1054344459056404 0.5958320558939572 0.056388901041461215 21.716749885984143 11681.834708490815 0.030714456637881013 0.014756016859294003 1.5830322896092255e-08 7.800510226605685 0.14931942697047473 TVSGPGT(ph)PEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVSGPGTPEPR 11 0 Q9H3U1 Q9H3U1 UNC45A Protein unc-45 homolog A 1 TVS(0.001)GPGT(0.999)PEPR 105.13 0.0063478 5045400.0 20738.0 22218.0 20945.0 19495.0 23060.0 18101.0 23862.0 15694.0 20797.0 14988.0 True False 24248.533805829687 24423.65620635337 21444.408234354833 18402.758353642774 18541.558537595098 17151.751695010647 21601.618614080515 15282.049129167515 21101.116780941473 17705.20575505728 1.3695708562383346 1.3794618681218684 1.2111922635086856 1.0393981639205885 1.0472376765403546 0.9687406027524676 1.2200715943620295 0.8631387480375585 1.1918029687350113 1.0 14.111885989167911 -5.512830170919735 2.435886666463321 1.0442850270320028 1.3785867306183441 0.6475059171684641 0.09707131611265732 0.16555586574899311 1.9396904245756712 0.025620750257805663 0.060514103887344094 3.0702223515663e-06 5.512830170919735 0.33430170358634137 TVSGPGTPEPRPAT(ph)PGASSVEQLR ddPTM_PC-9_AZD4547_30min_R2 2 TVSGPGTPEPRPATPGASSVEQLR 24 1 Q9H3U1 Q9H3U1 UNC45A Protein unc-45 homolog A 1 TVS(0.001)GPGT(0.142)PEPRPAT(0.8)PGAS(0.028)S(0.028)VEQLR;TVSGPGTPEPRPAT(0.435)PGAS(0.282)S(0.282)VEQLR 74.742 0.00021299 34057000.0 39528.0 37915.0 48690.0 83133.0 64078.0 63288.0 52836.0 50442.0 47527.0 57405.0 True False 52097.08176652405 50170.282281764186 48044.33878651915 63967.97124204657 55181.875766792036 59330.591355244534 57538.30164310541 42647.34794184717 50039.18019170646 55395.26842272213 0.9404608597429374 0.9056781149414063 0.8673004058738748 1.1547551454016978 0.9961478179995141 1.0710407773908033 1.0386862142093032 0.7698734775758213 0.903311449090863 1.0 15.75747513353878 -10.322227986715845 3.9097144905856487 1.0000007003223919 0.9630954349979327 0.01209339724113978 0.10444456803707297 112748392.01221234 229192235.52468497 1230.3094559300491 0.027973846545320247 4.761809457963185e-11 10.322227986715845 -0.03690526532445915 TVSGPGTPEPRPAT(ph)PGASSVEQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVSGPGTPEPRPATPGASSVEQLR 24 1 Q9H3U1 Q9H3U1 UNC45A Protein unc-45 homolog A 1 TVSGPGTPEPRPAT(0.93)PGAS(0.035)S(0.035)VEQLR;TVSGPGT(0.001)PEPRPAT(0.587)PGAS(0.206)S(0.206)VEQLR 87.652 1.2762e-05 24425000.0 28141.0 28954.0 37869.0 39587.0 48775.0 32631.0 40175.0 42664.0 32406.0 27028.5 True False 32904.71548991479 31828.361769680258 38771.94057898224 37369.06873278563 39217.88888426712 30919.772916407535 36369.33315818811 41544.11520624461 32879.8764438712 31928.55309251174 1.0305733364920941 0.9968620149324907 1.214334406781355 1.1703965608623168 1.2283014758180497 0.9684050770111222 1.139084914145949 1.3011587178996855 1.0297953793459742 1.0 14.962559555271246 -5.244608428625196 24.25290631398268 1.1414920130747555 1.013717640466521 0.1728874456416689 0.10109405072420999 876.4427174028575 1262919.5678766107 0.025229614253455733 0.0663125369872894 5.693660549583271e-06 5.244608428625196 -0.12777437260823454 TVSGPGTPEPRPAT(ph)PGASSVEQLR ddPTM_PC-9_Lapatinib_30min_R1 2 TVSGPGTPEPRPATPGASSVEQLR 24 1 Q9H3U1 Q9H3U1 UNC45A Protein unc-45 homolog A 1 TVSGPGT(0.025)PEPRPAT(0.657)PGAS(0.159)S(0.159)VEQLR;TVSGPGTPEPRPAT(0.928)PGAS(0.02)S(0.052)VEQLR 85.397 1.561e-05 24893000.0 32968.0 38461.0 43810.0 32713.0 36546.0 38559.0 33620.0 34624.0 45886.0 24734.0 True False 32497.870274409266 38371.945917536774 40208.1109114905 35118.82314736895 34396.43613220049 36909.921455419186 35360.679096076594 36232.75744112638 40717.83547899876 29009.238944016637 1.1202593193542634 1.3227491418023314 1.3860450110079054 1.210608220889313 1.1857062571886259 1.2723505613728663 1.2189454250874094 1.2490075148489768 1.4036161223525343 1.0 14.824224826547079 -10.622919830443415 4.5046233805338245 0.9999802254902338 1.2633316133562216 0.47189999865438004 0.08354672490689632 1.9516269158062775e-05 3.8988861093579675e-06 0.08090963893069458 0.019621738195826074 2.3827592795165714e-11 10.622919830443415 0.2633513878659878 TVSGPGTPEPRPAT(ph)PGASSVEQLRK ddPTM_PC-9_AZD4547_30min_R2 1 TVSGPGTPEPRPATPGASSVEQLRK 25 2 Q9H3U1 Q9H3U1 UNC45A Protein unc-45 homolog A 1 TVSGPGT(0.001)PEPRPAT(0.997)PGAS(0.001)S(0.001)VEQLRK 70.718 0.0037046999999999996 16475000.0 10455.0 8402.5 14038.0 27297.0 20336.0 12696.0 10240.0 17466.0 11662.0 14532.0 True False 13779.47252249062 11118.443805156896 13851.846947733738 21004.098384445926 17512.69742491156 11902.11711297852 11151.340162491464 14767.031028751877 12278.429511555136 14023.239103196554 0.9826169561174801 0.7928584632506538 0.987777990933368 1.497806478936675 1.248833974521592 0.8487423643989261 0.7952043091064139 1.0530399517602018 0.8755772772038313 1.0 13.77553200267725 -6.77856765213668 24.987701663002007 0.9103709814404467 1.100451394326653 0.20150752646557235 0.18648379386187347 467.1721279922516 681533.0175822012 0.07433163458520813 0.06571483814418125 1.66506943172177e-07 6.77856765213668 0.19008041288620625 TVSGPGTPEPRPAT(ph)PGASSVEQLRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVSGPGTPEPRPATPGASSVEQLRK 25 2 Q9H3U1 Q9H3U1 UNC45A Protein unc-45 homolog A 1 T(0.002)VS(0.009)GPGT(0.133)PEPRPAT(0.839)PGAS(0.005)S(0.011)VEQLRK 40.994 0.042308 29644000.0 62343.0 25051.0 63155.0 74975.0 92344.0 109220.0 81656.0 118420.0 92168.0 59001.0 True False 72896.43856962294 27537.897723708647 64660.85471667127 70774.39382222966 74249.85609695052 103492.31092917861 73920.9525417549 115311.60047636145 93515.78263527511 69697.41424834097 1.0458987518515885 0.39510644721463456 0.9277367806827986 1.0154522170657763 1.0653172272989728 1.4848802074697065 1.0605982063891914 1.654460236724008 1.3417396275572893 1.0 16.088817513113824 -6.120846098795027 1.2456302231320149 1.3351623755365187 0.7241521196191957 0.45779239518210146 0.24011809305098256 0.36343199237700546 1.1484393341285906 0.08883642622726687 0.14788596086926303 7.571011418900936e-07 6.120846098795027 -0.611010255917323 TVSLGAGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVSLGAGAK 9 0 P06748;P06748-3;P06748-2;E5RGW4 P06748 NPM1 Nucleophosmin 0 ; 111.95 0.010140999999999999 15444300.0 65655.0 78352.0 84641.0 69411.0 71973.0 59537.0 80041.0 53274.0 65349.0 58612.0 False True 76769.09475464103 86130.26874967132 86659.16244278011 65522.12670349827 57870.40731250355 56414.77491110152 72458.93703334246 51875.61394846883 66304.60549683812 69237.89162766331 1.1087728547177296 1.2439759028603758 1.2516146925559517 0.9463333611579754 0.8358198950324768 0.8147962565711859 1.0465214253345665 0.7492373428618737 0.9576346699492331 1.0 16.079274173222426 -5.836423756637395 5.052290612906045 0.8917663560456899 1.2054692163577672 0.6860364361698834 0.09128943378314573 0.10377659441837755 4.7756149090848465 0.024906977703437222 0.03817178387618329 1.4573915373117968e-06 5.836423756637395 0.3137028603120773 TVSLGAGAK ddPTM_PC-9_Lapatinib_30min_R1 2 TVSLGAGAK 9 0 P06748;P06748-3;P06748-2;E5RGW4 P06748 NPM1 Nucleophosmin 0 ; 115.49 0.0091017 47253000.0 204987.0 185501.0 180914.0 165578.0 164023.0 143777.0 173780.0 155023.0 144135.0 172404.0 False True 202063.84778998772 185071.48383164758 166039.94926823548 177755.15847201634 154375.48962162537 137627.99287055692 182777.47808792972 162225.93451928513 127900.99849116243 202203.80168611015 0.9993078572462268 0.9152720289549362 0.8211514713555514 0.8790891021324786 0.7634648227893818 0.6806399866022446 0.9039270110839124 0.8022892406895276 0.6325350830431407 1.0 17.625450596416307 -4.752269184471287 0.9300055973566969 0.7924227324977107 1.124037991332844 0.2749580431513965 0.10014787435464378 2.7991821679626736 1.8330882009212637 0.03361409312037434 0.956846618535994 1.769012149063206e-05 4.752269184471287 0.3316152588351333 TVSLGAGAKDELHIVEAEAMNY(ph)EGSPIK ddPTM_PC-9_AZD4547_30min_R2 2 TVSLGAGAKDELHIVEAEAMNYEGSPIK 28 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 TVSLGAGAKDELHIVEAEAMNY(0.765)EGS(0.235)PIK;TVSLGAGAKDELHIVEAEAMNY(0.818)EGS(0.182)PIK 69.704 0.00010672 6688900.0 37799.5 35166.0 49817.7 51896.8 46827.5 47332.5 45359.6 51190.3 47920.0 46764.7 True False 49818.95472155753 46532.72179138918 49157.08474769305 39932.794557567264 40326.309926487316 44372.79129253745 49396.516526811305 43280.015371070505 50452.953369381044 45127.482087066855 1.1039604342524398 1.0311393332694947 1.0892937623431254 0.8848886024822479 0.8936086850288615 0.9832764701324718 1.0945994379103177 0.9590611611693306 1.1180094930188986 1.0 15.461718664374144 -10.496180995468968 15.028381698495835 0.9999860667251622 1.0120405762105107 7.294726136397589e-05 0.08164274875857812 0.0 0.0 0.08229683413254586 0.019959914104848438 3.1902080349883414e-11 10.496180995468968 0.012054509485348475 TVSLGAGAKDELHIVEAEAMNY(ph)EGSPIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVSLGAGAKDELHIVEAEAMNYEGSPIK 28 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 TVSLGAGAKDELHIVEAEAMNY(0.531)EGS(0.469)PIK 55.588 0.010023 0.0 1180.5 570.68 491.33 2014.1 3399.2 712.52 1768.1 1184.8 2112.4 594.01 True False 1380.3353340622025 627.333338907271 503.04517057940143 1901.2565068003018 2733.1511613613707 675.1541968802271 1600.6127680645288 1153.700255399367 2143.289853731825 701.699310819427 1.9671322356726861 0.8940201725076327 0.7168956315376138 2.709503169641227 3.8950460962683073 0.9621702436785906 2.2810522162197553 1.644151900408887 3.0544277594186955 1.0 9.454709135230424 -5.761564511058506 24.999999910454765 2.267561462794047 1.162816383216972 0.21416751591535277 0.8989315821781698 4.864959678980433 972325.3845977648 0.24857317571819548 0.3969237212244523 1.7315518031289038e-06 5.761564511058506 -1.1047450795770748 TVSLGAGAKDELHIVEAEAMNY(ph)EGSPIK ddPTM_PC-9_Lapatinib_30min_R1 1 TVSLGAGAKDELHIVEAEAMNYEGSPIK 28 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 TVSLGAGAKDELHIVEAEAMNY(0.894)EGS(0.106)PIK 68.192 0.00013675 4471900.0 13276.0 14000.0 13435.0 15503.0 18405.0 16057.0 18599.0 17849.0 17537.0 16271.0 True False 13086.681805479779 13967.583860157432 12330.42616059975 16643.14233649194 17322.454085622223 15370.279540695185 19561.96521439407 18678.329700978065 15561.798387203084 19083.42067025532 0.685761846977337 0.7319224420770765 0.6461329115811385 0.8721257380461691 0.9077226973580341 0.8054258094646688 1.02507645523345 0.9787726227767616 0.8154616856221553 1.0 14.220032174671372 -5.865450682768938 4.698295278979568 0.9177978916582775 0.6929272221927263 0.6889930029168744 0.07034593311350795 0.12305328728393716 4.55999313354648 0.02031961866476882 0.03109130967009993 1.3631677948293024e-06 5.865450682768938 -0.22487066946555123 TVSLGAGAKDELHIVEAEAMNYEGS(ph)PIK ddPTM_PC-9_AZD4547_30min_R2 11 TVSLGAGAKDELHIVEAEAMNYEGSPIK 28 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 TVSLGAGAKDELHIVEAEAMNY(0.091)EGS(0.909)PIK;TVSLGAGAKDELHIVEAEAMNY(0.045)EGS(0.955)PIK;TVSLGAGAKDELHIVEAEAMNY(0.009)EGS(0.991)PIK;TVSLGAGAKDELHIVEAEAMNY(0.47)EGS(0.53)PIK;TVSLGAGAKDELHIVEAEAMNY(0.112)EGS(0.888)PIK;TVSLGAGAKDELHIVEAEAMNY(0.013)EGS(0.987)PIK;TVSLGAGAKDELHIVEAEAMNY(0.091)EGS(0.909)PIK;TVSLGAGAKDELHIVEAEAMNY(0.466)EGS(0.534)PIK;TVSLGAGAKDELHIVEAEAMNYEGS(1)PIK;TVSLGAGAKDELHIVEAEAMNYEGS(1)PIK;TVSLGAGAKDELHIVEAEAMNY(0.028)EGS(0.972)PIK 93.553 7.4928e-09 73582600.0 288449.4 274596.60000000003 338796.89999999997 324252.3 328141.2 367825.6 318013.5 374069.8 353038.10000000003 335822.6 True False 380170.3090797617 363354.58092081477 334304.2317400381 249500.94188309633 282584.4585094118 344825.40708503337 346316.08542621846 316265.90767886175 371698.9732244346 324065.5529904436 1.173127799519539 1.1212379025410633 1.031594468017699 0.7699088643662595 0.8719978285311458 1.0640606627363507 1.0686605911379634 0.9759318902005859 1.1469869901149157 1.0 18.305926149918086 -5.278922385377717 3.5977530332612626 0.9816469394523472 1.1546428852840367 0.28607129734873915 0.10033267583794958 0.30139203726669633 8.465590989835665 0.02915554393761392 0.07661615002369795 5.2611128158434745e-06 5.278922385377717 0.17299594583168953 TVSLGAGAKDELHIVEAEAMNYEGS(ph)PIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TVSLGAGAKDELHIVEAEAMNYEGSPIK 28 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 TVSLGAGAKDELHIVEAEAMNY(0.133)EGS(0.867)PIK;TVSLGAGAKDELHIVEAEAMNY(0.469)EGS(0.531)PIK;TVSLGAGAKDELHIVEAEAMNY(0.06)EGS(0.94)PIK 74.058 1.5645e-05 17754700.0 48966.3 51929.1 52659.5 69215.2 66280.7 50904.9 61554.1 56461.8 54197.3 43985.2 True False 57255.3274614909 57084.27786053403 53915.10219226588 65337.29674270599 53293.47263498605 48235.35743104511 55723.25003490795 54979.73757622211 54989.83298128189 51959.36857334841 1.1019250047403184 1.0986330170650755 1.037639672548304 1.2574690289100152 1.0256759098170016 0.9283283988132708 1.072438937671967 1.058129440095293 1.0583237343166618 1.0 15.665096278356144 -6.4507577463576835 24.999938097358584 1.0242323067962988 1.1191512270587993 0.36931939117855095 0.06396371849673044 175.8212451165659 60945.926883077394 0.020083579767895477 0.02277263129110223 3.5419485929135733e-07 6.4507577463576835 0.09491892026250048 TVSLGAGAKDELHIVEAEAMNYEGS(ph)PIK ddPTM_PC-9_Lapatinib_30min_R1 5 TVSLGAGAKDELHIVEAEAMNYEGSPIK 28 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 TVSLGAGAKDELHIVEAEAMNY(0.029)EGS(0.971)PIK;TVSLGAGAKDELHIVEAEAMNY(0.463)EGS(0.537)PIK;TVSLGAGAKDELHIVEAEAMNY(0.152)EGS(0.848)PIK;TVSLGAGAKDELHIVEAEAMNY(0.054)EGS(0.946)PIK;TVSLGAGAKDELHIVEAEAMNY(0.017)EGS(0.983)PIK 70.345 6.9786e-05 27448600.0 167555.0 192072.0 216708.0 215199.0 255038.0 232689.0 219260.0 230176.0 212859.0 194786.0 True False 165165.63497417627 191627.2690848684 198891.1047570709 231025.45234281907 240037.16626400038 222737.43389455203 230612.20995258057 240870.81725880003 188884.57791535987 228454.5005639702 0.722969495310633 0.8387983979821413 0.8705939443787793 1.0112536709607476 1.0507000985817168 0.9749750315476173 1.0094448101625653 1.0543491884124783 0.8267929826248696 1.0 17.801547338420534 -5.2736209218016725 1.4823665374751045 0.9944633234054173 0.7292053287656918 0.6420582083490596 0.06412214516891004 0.33292171695625594 1.1835648581007823 0.018940394735629626 0.09858287524938787 5.325729179415442e-06 5.2736209218016725 -0.26525799463972555 TVSLPLS(ph)SPNIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVSLPLSSPNIK 12 0 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;A0A0A0MQZ8;H0Y7Y3 Q8IWZ3-6 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 1 TVSLPLS(0.776)S(0.224)PNIK 96.665 0.0042126 20955000.0 76258.0 62809.0 65756.0 82652.0 76572.0 70716.0 79844.0 75269.0 66865.0 59951.0 True False 89166.97323584513 69044.26242977983 67323.87242101878 78021.2764013995 61568.26627670133 67007.52847159676 72280.59829949895 73293.2685040978 67842.7741288479 70819.6417281452 1.259071227416395 0.9749309759970193 0.9506384214629946 1.101689792514048 0.8693670961093385 0.9461715258150842 1.0206292567387154 1.0349285412293963 0.9579655089088903 1.0 16.111861924798532 -4.760275359883956 24.99643707228609 0.984137109142764 1.2590715561140888 0.663760435559969 0.05872573990051269 17.675018860703307 379395.01707691635 0.01457329230630518 0.08746756050120937 1.7366993434991025e-05 4.760275359883956 0.27493444697132485 TVSLPLSS(ph)PNIK ddPTM_PC-9_AZD4547_30min_R2 2 TVSLPLSSPNIK 12 0 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;A0A0A0MQZ8;H0Y7Y3 Q8IWZ3-6 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 1 TVSLPLS(0.182)S(0.818)PNIK;TVSLPLS(0.383)S(0.617)PNIK 229.56 9.8793e-16 49561000.0 334420.0 271757.0 368070.0 448390.0 453080.0 423150.0 382570.0 446630.0 398830.0 442820.0 True False 440758.60363188 359597.1357522193 363189.15130733425 345020.6130564422 390177.6627300804 396690.36360718816 416617.9888637066 377613.5960363818 419911.3395724173 427317.0065839179 1.0314557970800593 0.8415231086329359 0.8499290824176687 0.8074113778307719 0.9130871383969973 0.928328050358756 0.9749623404747169 0.8836849229454312 0.982669383859296 1.0 18.704947209724125 -6.6726956565908875 3.0507387961331762 0.9492439327613683 0.8762038923941893 0.21454085593470262 0.0632509719474123 0.40490216635038223 7.578689799548271 0.022512752144385542 0.02201597250765549 2.1247329035004144e-07 6.6726956565908875 -0.07304004036717904 TVSLPLSS(ph)PNIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVSLPLSSPNIK 12 0 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;A0A0A0MQZ8;H0Y7Y3 Q8IWZ3-6 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 1 TVSLPLS(0.054)S(0.946)PNIK 81.676 0.012943000000000001 24165000.0 75042.0 48115.0 58678.0 65241.0 65997.0 66099.0 67383.0 70005.0 55858.0 42074.0 True False 87745.12845294017 52891.53921904278 60077.1060575542 61585.75828417584 53065.361613428635 62632.65207936078 60999.994429326485 68167.44292642857 56674.81757704612 49701.68314239925 1.7654357539873138 1.064180041297683 1.2087539547791277 1.2391081023901702 1.0676773553401036 1.2601716505236509 1.2273225084662964 1.3715318801402252 1.1402997643896342 1.0 15.601007088883804 -4.753640903006572 24.999165904994328 1.1909906581474468 1.7654367888775186 0.7358687532351641 0.10567221561236981 145.5078138806503 466409.1298455715 0.025506978443818242 0.2693857713619224 1.763433541226956e-05 4.753640903006572 0.5744461307300719 TVSLPLSS(ph)PNIK ddPTM_PC-9_Lapatinib_30min_R1 2 TVSLPLSSPNIK 12 0 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;A0A0A0MQZ8;H0Y7Y3 Q8IWZ3-6 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 1 TVSLPLS(0.324)S(0.676)PNIK;TVSLPLS(0.389)S(0.611)PNIK 257.2 1.5386e-39 37681000.0 278970.0 235454.0 251154.0 239402.0 263754.0 222601.0 179736.0 165475.0 217694.0 175036.0 True False 274991.8366431682 234908.8207292501 230505.08760247633 257008.42170166093 248240.50828031512 213080.87413827554 189041.85062499775 173163.5725961868 193175.00930055242 205290.7393791903 1.3395238259395312 1.1442738305664757 1.1228226285293508 1.251924088143808 1.2092143514656684 1.0379468396024245 0.920849382669038 0.8435040621892752 0.9409825785845165 1.0 17.647309023690184 -6.960368324919345 2.5968153562598943 0.913804303142703 1.2081244882179278 0.8060124137897889 0.06655066672172477 0.12040382345345574 1.6446586126947291 0.027254868602496877 0.022369635214693602 1.0955486677896041e-07 6.960368324919345 0.29432018507522484 TVSPGS(ph)VSPIHGQGQVVENLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVSPGSVSPIHGQGQVVENLK 21 0 A0A087WVF7;Q9NZM3-4;Q9NZM3-3;Q9NZM3-2;Q9NZM3 A0A087WVF7 ITSN2 Intersectin-2 1 T(0.038)VS(0.038)PGS(0.499)VS(0.424)PIHGQGQVVENLK;T(0.111)VS(0.349)PGS(0.373)VS(0.167)PIHGQGQVVENLK 68.192 0.0019503 11359500.0 22716.0 18465.199999999997 22549.0 27522.0 31280.0 30099.0 27570.0 21440.8 27069.0 23373.3 True False 26561.37013854891 20298.30302374455 23086.653677558716 25980.03156752789 25150.908545358823 28520.555453738787 24958.370010485294 20878.001718405427 27464.83291548323 27610.694267059 0.9619957354798576 0.7351609064014549 0.8361489738091192 0.9409409019650559 0.9109118482169125 1.0329532165283253 0.9039385163256084 0.7561563471192383 0.9947172153599271 1.0 14.752939544297243 -5.75443592106683 23.94731545096043 0.9259505887917295 0.8335077155135711 0.1717502120353357 0.08809963692238777 167.42089743978812 572458.6974957506 0.024091544737199978 0.04054296038602577 1.7602083584505702e-06 5.75443592106683 -0.09244287327815848 TVSPGSVS(ph)PIHGQGQVVENLK ddPTM_PC-9_AZD4547_30min_R2 3 TVSPGSVSPIHGQGQVVENLK 21 0 A0A087WVF7;Q9NZM3-4;Q9NZM3-3;Q9NZM3-2;Q9NZM3 A0A087WVF7 ITSN2 Intersectin-2 1 T(0.003)VS(0.011)PGS(0.097)VS(0.889)PIHGQGQVVENLK;T(0.012)VS(0.012)PGS(0.199)VS(0.777)PIHGQGQVVENLK;T(0.001)VS(0.005)PGS(0.067)VS(0.926)PIHGQGQVVENLK 95.834 0.00019076 133931000.0 90493.0 86854.0 124563.0 184829.0 165652.0 135367.0 130704.0 152041.0 127309.0 138878.0 True False 119267.89162866973 114927.85697745872 122911.2132319815 142219.52962958394 142654.07916165655 126902.48009078174 142336.40279280112 128546.557004607 134038.29383352524 134015.92349117328 0.8899531378189183 0.8575686678384024 0.9171388744717103 1.061213667187474 1.0644561888278314 0.9469209089854158 1.0620857513411521 0.9591886818813251 1.000166923017573 1.0 17.032044903305746 -5.597183603358954 5.18459968195616 1.0127156623956075 0.8765409744172128 0.6853253932926353 0.03953838602475282 0.10897740921720876 5.271603610180142 0.010888551520771 0.019395751195231896 2.528228930459074e-06 5.597183603358954 -0.13617468797839472 TVSPGSVS(ph)PIHGQGQVVENLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVSPGSVSPIHGQGQVVENLK 21 0 A0A087WVF7;Q9NZM3-4;Q9NZM3-3;Q9NZM3-2;Q9NZM3 A0A087WVF7 ITSN2 Intersectin-2 1 TVS(0.001)PGS(0.046)VS(0.953)PIHGQGQVVENLK;TVS(0.001)PGS(0.025)VS(0.974)PIHGQGQVVENLK 93.21 0.00022695 107598000.0 100790.0 119182.0 140909.0 151473.0 185183.0 165744.0 154717.0 122441.0 144991.0 127113.0 True False 117851.75630675946 131013.60131360183 144268.80496035825 142986.45889209214 148897.72049728822 157052.09286436372 140061.08570592114 119227.053486963 147111.2190789773 150157.58067404584 0.784853856713274 0.8725074067222703 0.9607826945049772 0.9522426923118827 0.9916097464336985 1.0459151789697791 0.9327606710044055 0.7940128826780635 0.9797122357632985 1.0 17.196117785327758 -4.939358252223034 2.2686850924004265 0.9534071736221345 0.7696354440986996 0.4341182588084751 0.06244042144781222 0.45854173152511696 3.630160126360949 0.018097503568511215 0.14962627002868412 1.1498514779711719e-05 4.939358252223034 -0.1837717295234349 TVSPGSVS(ph)PIHGQGQVVENLK ddPTM_PC-9_Lapatinib_30min_R1 2 TVSPGSVSPIHGQGQVVENLK 21 0 A0A087WVF7;Q9NZM3-4;Q9NZM3-3;Q9NZM3-2;Q9NZM3 A0A087WVF7 ITSN2 Intersectin-2 1 T(0.004)VS(0.005)PGS(0.219)VS(0.772)PIHGQGQVVENLK;TVS(0.001)PGS(0.02)VS(0.979)PIHGQGQVVENLK 125.91 5.158200000000001e-06 115834000.0 123544.0 81211.0 112839.0 99208.0 99968.0 90664.0 79575.0 85555.0 106073.0 72617.0 True False 121782.23990480512 81022.96091908903 103561.81299113597 106504.08726818651 94088.07878464989 86786.51206810655 83695.00413653474 89530.19763388293 94125.94174179129 85168.75169392987 1.4298934466299658 0.9513226307491329 1.215960207604135 1.2505066136337097 1.1047253471880547 1.0189947644177104 0.982696147024776 1.0512094618414363 1.105169911143594 1.0 16.378036584115407 -6.5143253008156945 4.161793302578628 1.0330027851473913 1.1931925207997993 0.3559143560445268 0.11308964880744027 0.2625854570448101 10.733217479427255 0.036252628107483 0.03866815241436136 3.0596707813621144e-07 6.5143253008156945 0.16018973565240802 TVSPPIRK ddPTM_PC-9_AZD4547_30min_R2 1 TVSPPIRK 8 1 Q9UHB6;Q9UHB6-4;F8VQE1;Q9UHB6-2;Q9UHB6-5;F8VS07;Q9UHB6-3 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 0 67.98100000000001 0.028375 4216000.0 22507.0 17554.0 30779.0 45282.0 40412.0 32708.0 16899.0 30154.0 29357.0 30890.0 False True 29663.757825317658 23227.987212820484 30370.850349358647 34842.934499926036 34801.49136189645 30662.763589421964 18402.978262299148 25494.39216998651 30908.75108649665 29808.550502184255 0.9951425790779063 0.7792390713905538 1.01886370983162 1.1688906006138367 1.167500290205199 1.0286566462591034 0.6173724636812061 0.8552711131699738 1.0369088924411731 1.0 14.863438602776766 TVSQQS(ph)FDGVSLDSSGPEDR ddPTM_PC-9_AZD4547_30min_R2 1 TVSQQSFDGVSLDSSGPEDR 20 0 H7C1J4;Q6BDS2 H7C1J4 UHRF1BP1 UHRF1-binding protein 1 1 TVSQQS(1)FDGVSLDSSGPEDR 289.22 5.1881999999999985e-107 4581300.0 14351.0 15866.0 19144.0 24894.0 20056.0 19707.0 15443.0 20803.0 15955.0 17355.0 True False 18914.319480656406 20994.3742234596 18890.13805153262 19155.072908466023 17271.570591759748 18474.718174658763 16817.39708294489 17588.37435538334 16798.34872722192 16747.406732450883 1.1293879573609906 1.2535895591990078 1.1279440664046116 1.1437635219875497 1.031298210384609 1.1031390393630869 1.004179175415761 1.0502147966170154 1.0030417840555774 1.0 14.031650096977774 -6.1702397417053145 0.8111197488588311 1.0179559509920142 1.199317167149933 0.7080645105601842 0.042056143937769186 0.3576899121954902 0.4962689667986441 0.02080799766596793 0.039805735077831576 6.757098632231241e-07 6.1702397417053145 0.18136121615791878 TVSQQS(ph)FDGVSLDSSGPEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVSQQSFDGVSLDSSGPEDR 20 0 H7C1J4;Q6BDS2 H7C1J4 UHRF1BP1 UHRF1-binding protein 1 1 T(0.001)VS(0.006)QQS(0.652)FDGVS(0.34)LDSSGPEDR;TVSQQS(1)FDGVSLDSSGPEDR 195.56 3.5459000000000003e-59 4360200.0 12593.400000000001 14268.6 16860.699999999997 11862.5 15472.3 15058.1 14781.3 13378.8 13915.599999999999 13750.3 True False 14725.213889012224 15685.092310107737 17262.72303256082 11197.882583743896 12440.61388383488 14268.426727729959 13381.108256655292 13027.62067601034 14119.089324271248 16243.12054268508 0.9065507979403361 0.9656452569498017 1.0627713429323105 0.6893923217719853 0.7659004839090098 0.878428913350372 0.8238015731947108 0.8020392782147513 0.8692350270483976 1.0 13.987541201664873 -5.750206406236703 24.998864764866788 0.8231901159447911 0.9770547265805163 0.3837254180078836 0.08397218206805157 212.48458664215954 472877.97439750633 0.02240650584280678 0.03836222707833565 1.7774344516826012e-06 5.750206406236703 0.1538646106357252 TVSQQS(ph)FDGVSLDSSGPEDR ddPTM_PC-9_Lapatinib_30min_R1 2 TVSQQSFDGVSLDSSGPEDR 20 0 H7C1J4;Q6BDS2 H7C1J4 UHRF1BP1 UHRF1-binding protein 1 1 TVSQQS(0.854)FDGVS(0.145)LDSSGPEDR;TVS(0.001)QQS(0.957)FDGVS(0.042)LDSSGPEDR 186.89 1.2705e-11 8206300.0 31240.8 28079.2 31409.0 28842.1 32348.0 34471.0 25823.7 29993.1 36781.0 29374.0 True False 30795.300463138945 28014.18433758092 28826.67326224617 30963.244248425104 30445.354238614935 32996.75568582572 27160.724829665487 31386.68892119476 32638.336458899274 34451.2567616053 0.8938803212967027 0.8131542059969705 0.8367379298154509 0.8987551444838012 0.8837226011605243 0.9577808993777968 0.7883812488354605 0.911046268598657 0.9473772374908987 1.0 15.072268992106427 -10.68872565916124 0.17655749801587994 1.1227604724744293 0.8303735852649853 0.4217567157606651 0.047812334879907006 24.37382113657687 0.8643114459226291 1.5585325946003692 0.2058475404748475 2.047737770122619e-11 10.68872565916124 -0.29238688720944406 TVSQQSFDGVS(ph)LDSSGPEDR ddPTM_PC-9_AZD4547_30min_R2 1 TVSQQSFDGVSLDSSGPEDR 20 0 H7C1J4;Q6BDS2 H7C1J4 UHRF1BP1 UHRF1-binding protein 1 1 TVSQQS(0.012)FDGVS(0.986)LDS(0.002)S(0.001)GPEDR 167.73 3.4876999999999995e-08 4289800.0 8385.2 8588.1 10638.0 11479.0 11171.0 11680.0 8657.5 12597.0 9289.2 15366.0 True False 11051.519177005097 11364.03537555108 10496.933169254284 8832.693898782094 9620.099475496025 10949.647753590822 9428.00072820019 10650.423100262651 9780.208147722346 14828.041017046391 0.7453121531226016 0.766388180507926 0.7079109881869733 0.5956750381677515 0.6487775063770534 0.7384419655302444 0.6358224068413159 0.7182623171880136 0.6595752019082608 1.0 13.85604039058039 -11.259533613753133 2.733255824143188 1.0590977261514778 0.689993401435152 0.7625067461901587 0.05178631993864777 22655094.777753998 18559133.044591125 9091035.275415227 0.014696233737763482 5.501313395076124e-12 11.259533613753133 -0.3691043247163258 TVSS(ph)DGCSTPSREEGGCSLASTPATTLHLLQLSGQR ddPTM_PC-9_AZD4547_30min_R2 1 TVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQR 36 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 T(0.098)VS(0.087)S(0.247)DGCS(0.087)T(0.087)PS(0.087)REEGGCS(0.11)LAS(0.141)T(0.056)PATTLHLLQLSGQR 60.815 8.4384e-05 25984000.0 776.66 615.04 1468.9 3043.1 3136.1 1178.2 802.19 1497.5 975.37 1402.7 True False 1023.6217244684415 813.8396522372748 1449.4214262377895 2341.5603104263246 2700.706648026412 1104.5269677466354 873.5833559520536 1266.0957841266425 1026.9260669426794 1353.5918999486516 0.7562262484780475 0.6012444757302018 1.0707964684871216 1.7298864676385486 1.995214841436967 0.8159970281947871 0.6453816368029336 0.9353600477179803 0.7586674144412624 1.0 10.402577125003512 -6.91719577402033 23.561925975237923 0.8148651276023702 1.2336636328459882 0.20305716419203013 0.3951344792615329 31.78808891987442 9040.262420324749 0.15936652244116692 0.14054804509697286 1.2100525354309998e-07 6.91719577402033 0.41879850524361806 TVSS(ph)DGCSTPSREEGGCSLASTPATTLHLLQLSGQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQR 36 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 T(0.093)VS(0.093)S(0.212)DGCS(0.191)T(0.191)PS(0.191)REEGGCS(0.016)LAS(0.008)T(0.003)PATTLHLLQLSGQR 52.63 0.00086944 12222000.0 1408.6 1738.8 2477.0 5378.6 2334.7 5323.8 7422.7 2066.5 5439.6 1144.6 True False 1647.0481588818438 1911.4165726711326 2536.0610740748125 5077.254479656477 1877.2322947841833 5044.610555985729 6719.568120305741 2012.2565646377382 5519.143859287839 1352.1069193513847 1.2181345537910158 1.413657858942141 1.8756364883417496 3.755068779687979 1.3883756291142308 3.7309257750161238 4.969701747794594 1.4882377538627136 4.081884191477559 1.0 10.400993523500404 -6.7638927500943185 24.999969964906075 3.2043867588308483 1.9998323849678836 0.15561816483299673 1.2803469966060967 119.01626079150336 1212770.8290578073 0.43538748114850656 0.401978961008309 1.7222938464416262e-07 6.7638927500943185 -1.2045543738629647 TVSS(ph)PIPYTPSPSSSR ddPTM_PC-9_Lapatinib_30min_R1 2 TVSSPIPYTPSPSSSR 16 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 T(0.089)VS(0.189)S(0.722)PIPYTPSPSSSR;TVS(0.065)S(0.935)PIPYTPSPSSSR 317.77 2.8347999999999993e-147 50466000.0 37340.0 82873.0 76213.0 66804.0 92972.0 71544.0 97004.0 90615.0 78277.0 81451.0 True False 36807.52475268263 82681.11266020195 69947.06133068769 71716.98901161099 87503.56974998485 68484.22989720962 102026.39247578279 94825.30370632117 69460.6199666475 95529.69682336441 0.385299294111026 0.8655016754955304 0.7322022748593107 0.7507297876619098 0.9159829106521716 0.7168894299312789 1.0680070791434715 0.9926264487330502 0.727110231440188 1.0 16.543661665575797 -4.563747393342292 2.420754623997234 0.8634039245244938 5.549719247855787e-106 0.5668705511920139 0.12409010919309946 1.1862271746693942 4.49649236104896 0.0328119336831736 2.738984745013821 2.730565549879079e-05 4.563747393342292 -0.8634039245244938 TVSS(ph)PIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTR 39 1 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 T(0.049)VS(0.155)S(0.483)PIPY(0.066)T(0.07)PS(0.016)PS(0.016)S(0.059)S(0.017)RPIS(0.017)PGLS(0.022)Y(0.021)AS(0.006)HT(0.002)VGFT(0.001)PPTSLTR 47.276 0.0018094 9693600.0 2839.4 6080.8 10941.0 8531.8 7096.6 12073.0 7947.2 9586.2 9096.1 6114.0 True False 3320.0543392937047 6684.461637392816 11201.874933973568 8053.790906468807 5706.0721733693545 11439.870626698172 7194.383683254578 9334.572407418473 9229.113254369464 7222.41980160263 0.45968725586360903 0.92551552263821 1.550986406451742 1.1151097731374877 0.7900499181871423 1.583938754731441 0.9961181821164935 1.29244389883667 1.2778422617197571 1.0 12.818266563725768 -4.887893627172778 3.609485796951765 1.2022953849011682 0.4488985281422192 0.4835654654560745 0.234386476820539 0.20194447781928945 4.517240633607718 0.05745103444638965 0.34260767550066806 1.29451287087896e-05 4.887893627172778 -0.753396856758949 TVSS(ph)PPT(ph)SPRPGSAATVSASTSNIIPPR ddPTM_PC-9_AZD4547_30min_R2 2 TVSSPPTSPRPGSAATVSASTSNIIPPR 28 1 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 2 T(0.054)VS(0.197)S(0.744)PPT(0.502)S(0.502)PRPGSAATVSASTSNIIPPR;T(0.022)VS(0.139)S(0.836)PPT(0.532)S(0.471)PRPGSAATVSASTSNIIPPR 105.71 1.1385000000000002e-09 202806000.0 363830.0 298790.0 464960.0 599450.0 511820.0 441090.0 377950.0 451670.0 404850.0 464550.0 True False 479520.37186587864 395368.02434309205 458794.3266005328 461256.06391017756 440762.6276562872 413508.5725711792 411586.8178138329 381874.77984406136 426249.5444823435 448286.24589801516 1.069674513223788 0.8819543940079706 1.0234405601302081 1.0289320007714737 0.9832169326840343 0.9224208334628499 0.9181339413823297 0.8518547765816077 0.9508423432186117 1.0 18.77406071043231 -6.735070368691983 4.278304454569724 0.9180664458412573 0.9953295760428996 0.25968961507441846 0.05699957014281303 0.2679492987961546 11.057144204135524 0.019320400254674897 0.018451637987077982 1.8404737655256972e-07 6.735070368691983 0.07726313020164233 TVSS(ph)PPT(ph)SPRPGSAATVSASTSNIIPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVSSPPTSPRPGSAATVSASTSNIIPPR 28 1 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 2 T(0.004)VS(0.055)S(0.701)PPT(0.616)S(0.623)PRPGSAATVSASTSNIIPPR;T(0.031)VS(0.156)S(0.771)PPT(0.512)S(0.466)PRPGS(0.039)AAT(0.004)VS(0.002)AS(0.004)T(0.011)S(0.004)NIIPPR 93.34 1.064e-07 82934000.0 174789.0 185836.0 214143.0 220740.0 243090.0 244970.0 237008.0 256227.0 227632.0 183762.0 True False 204377.32545988806 204284.56993266192 219248.9812618499 208372.65344873577 195458.25953616595 232123.34195496183 214556.88645067514 249501.312744947 230960.6873625649 217076.59594080792 0.9414986658240087 0.941071371822902 1.010007459862851 0.9599038189522489 0.9004114823574217 1.0693153766712686 0.9883925326946814 1.1493699339793435 1.0639594119374476 1.0 17.72784466496727 -6.776696092301558 24.990473995209797 1.0594296675321209 0.9538700578668556 0.5352240867886601 0.04811253376250896 190.01286214439216 311238.89331897843 0.01704001633991766 0.015083003953843247 1.6722604082123294e-07 6.776696092301558 -0.10555960966526523 TVSS(ph)PPT(ph)SPRPGSAATVSASTSNIIPPR ddPTM_PC-9_Lapatinib_30min_R1 3 TVSSPPTSPRPGSAATVSASTSNIIPPR 28 1 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 2 T(0.045)VS(0.171)S(0.701)PPT(0.808)S(0.26)PRPGS(0.005)AAT(0.001)VS(0.001)AS(0.002)T(0.003)S(0.003)NIIPPR;T(0.024)VS(0.2)S(0.557)PPT(0.605)S(0.605)PRPGS(0.004)AAT(0.001)VSAS(0.001)T(0.002)S(0.002)NIIPPR;T(0.138)VS(0.171)S(0.64)PPT(0.784)S(0.241)PRPGS(0.003)AAT(0.001)VS(0.006)AS(0.006)T(0.006)S(0.006)NIIPPR 62.678000000000004 0.0029444000000000002 90299900.0 241461.0 227052.0 237513.0 235349.0 216640.0 209092.0 197949.0 195556.0 245436.0 203249.0 True False 238017.72186147538 226526.2750440328 217985.59796669384 252657.3505612493 203897.66113062765 200149.6225772584 208197.8306481041 204642.24567227677 217792.41312434158 238380.31883773115 0.9984789139555493 0.9502725566796161 0.9144446111555028 1.05989182241692 0.8553460374781345 0.839623101240598 0.8733851505158331 0.858469552646163 0.9136342051484374 1.0 17.862905603327064 -6.288706360314539 24.99185115794163 0.8796425916620512 0.9738557967395748 0.38321470372490285 0.05514982507449975 712.885562714276 653401.0789927363 0.016452655949352198 0.018660175738668676 5.143913296274843e-07 6.288706360314539 0.09421320507752362 TVSS(ph)PPTSPRPGSAATVSAST(ph)SNIIPPR ddPTM_PC-9_Lapatinib_30min_R1 1 TVSSPPTSPRPGSAATVSASTSNIIPPR 28 1 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 2 T(0.005)VS(0.056)S(0.387)PPT(0.34)S(0.34)PRPGS(0.053)AAT(0.011)VS(0.015)AS(0.136)T(0.466)S(0.191)NIIPPR 63.461999999999996 0.0020029 80466000.0 213610.0 184170.0 197600.0 174580.0 213450.0 186010.0 174480.0 167410.0 253920.0 187140.0 True False 210563.88222872393 183743.56568037104 181354.0907580579 187419.19558180732 200895.29065884603 178054.78591048843 183513.72066280316 175188.47976025174 225320.85570386084 219486.89965162388 0.9593460136479087 0.8371504904029091 0.8262638501245791 0.8538969563982389 0.9152951314074461 0.8112319513971097 0.8361032979830759 0.798172829623618 1.0265799738458048 1.0 17.74377530772066 -8.270678478458887 24.991903877455663 1.0132900210795135 0.853077441105681 0.6512388586221018 0.04641583143294143 435.5923249553811 1178269.7408572498 0.04227665013642137 0.01150835583693633 5.361934711004692e-09 8.270678478458887 -0.16021257997383254 TVSS(ph)PPTSPRPGSAATVSASTSNIIPPR ddPTM_PC-9_AZD4547_30min_R2 1 TVSSPPTSPRPGSAATVSASTSNIIPPR 28 1 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 1 T(0.022)VS(0.061)S(0.331)PPT(0.286)S(0.286)PRPGS(0.007)AATVS(0.001)AS(0.001)T(0.002)S(0.002)NIIPPR 44.933 0.015625999999999998 73482000.0 5069.9 10652.0 15481.0 14267.0 18574.0 11586.0 9357.6 12124.0 11355.0 13682.0 True False 6682.022739528945 14095.05068878682 15275.711824894299 10977.963572952702 15995.320710577656 10861.525588450626 10190.408271926774 10250.514381803947 11955.202118308056 13202.997344476687 0.5060989232361156 1.0675644568453475 1.1569881767252423 0.8314751027004635 1.211491625215626 0.8226560458254134 0.7718253670777118 0.7763778265161981 0.9054915188110197 1.0 13.688577866945991 TVSS(ph)PPTSPRPGSAATVSASTSNIIPPR ddPTM_PC-9_Lapatinib_30min_R1 1 TVSSPPTSPRPGSAATVSASTSNIIPPR 28 1 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 1 T(0.026)VS(0.098)S(0.332)PPT(0.271)S(0.271)PRPGS(0.001)AATVSASTSNIIPPR 68.41199999999999 9.8052e-05 53881000.0 44466.0 37939.0 43227.0 37962.0 36170.0 29987.0 29486.0 23812.0 40404.0 25170.0 True False 43831.90668593431 37851.1545764652 39673.0429210454 40753.852117519666 34042.55171295603 28704.525913111192 31012.640803893948 24918.392449979823 35853.27604701793 29520.600963083165 1.4847904600840638 1.282194580787829 1.3439104092311103 1.380522441547995 1.153179495076261 0.972355744011021 1.050542326109033 0.8441018013536171 1.2145171465802493 1.0 14.849434470786335 -6.451018146305733 2.8857246050263234 1.0091734116896338 1.365430439852884 0.7453302335953742 0.09796996655023742 0.1302416171655032 2.1274557161822205 0.03144216423778924 0.03505349498857844 3.5398255017531447e-07 6.451018146305733 0.3562570281632502 TVSS(ph)SGCEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVSSSGCEGK 10 0 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 T(0.005)VS(0.084)S(0.899)S(0.011)GCEGK 94.76700000000001 0.0061754 4839900.0 20206.0 32638.0 19577.0 19527.0 57398.0 40814.0 28248.0 41114.0 43796.0 44512.0 True False 23626.47671330865 35878.084942972404 20043.789926185942 18432.965497388155 46151.2739349906 38673.6419910593 25572.14494219038 40034.80106388386 44436.43364610823 52581.673243201876 0.44932911518488516 0.6823306055139843 0.38119345942984695 0.3505587471918516 0.8777064533783613 0.7354966018708676 0.4863318978822441 0.7613831701154515 0.8450935640746898 1.0 15.682272431381037 -8.06596049008351 0.3038256077953163 1.0516770396695503 0.44615833682317196 0.5001324511108591 0.15191225855018992 1.4405148871500997 0.47626291744266336 0.3233204238673061 0.2740286211840262 8.590916737679361e-09 8.06596049008351 -0.6055187028463783 TVSS(ph)SNGGESSSR ddPTM_PC-9_AZD4547_30min_R2 1 TVSSSNGGESSSR 13 0 Q8WW12;Q8WW12-2 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 1 T(0.144)VS(0.092)S(0.76)S(0.004)NGGESSSR 152.11 0.00013763 3394700.0 6065.3 5122.0 5640.9 8648.9 7270.5 5959.3 4872.8 6375.8 6579.4 5475.1 True False 7993.939233922745 6777.586333830839 5566.097980301416 6655.029729172965 6261.1165729651575 5586.664028936109 5306.4697601355865 5390.566611308612 6927.173651888683 5283.4184154907425 1.5130240698871926 1.2828032536585148 1.0535031569678204 1.2596067935222999 1.1850502989897314 1.0573957217842647 1.0043629602715656 1.020280089024128 1.3111158547614787 1.0 12.367255951991377 -1.522878999319546 0.7645616944413951 1.0984202814652848 83.50609163824537 0.5881250253541428 0.10418638157465343 291.722823117476 1.1846065926671154 0.039033881479009214 41478.745098680614 0.029999982451598305 1.522878999319546 82.40767135678009 TVSS(ph)SNGGESSSR ddPTM_PC-9_Lapatinib_30min_R1 1 TVSSSNGGESSSR 13 0 Q8WW12;Q8WW12-2 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 1 TVS(0.369)S(0.619)S(0.012)NGGESSSR 159.58 0.00027006 2193600.0 2362.5 2324.9 4826.6 2089.8 3500.0 3375.6 4867.6 5572.9 3734.1 4064.6 True False 2328.810316770561 2319.51683689143 4429.775579214792 2243.490863368436 3294.136881264753 3231.2334569079326 5119.620510650284 5831.83727887168 3313.526336183788 4767.1606942609405 0.48851097458790393 0.4865614955425848 0.9292272409754683 0.47061364347740897 0.6910060500436828 0.6778108950256134 1.073934956044939 1.2233355770642418 0.6950733463155239 1.0 12.218914542103645 -7.190360429798333 4.762725691968154 1.0165414310633454 0.6229016179256698 0.520803011473284 0.17588514066247912 0.17477360070031 7.585932795687301 0.06857565847045562 0.052009635784185985 6.451186097870332e-08 7.190360429798333 -0.3936398131376756 TVSSDGCS(ph)TPSREEGGCSLASTPATTLHLLQLSGQR ddPTM_PC-9_Lapatinib_30min_R1 1 TVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQR 36 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 T(0.075)VS(0.07)S(0.065)DGCS(0.214)T(0.214)PS(0.214)REEGGCS(0.069)LAS(0.059)T(0.017)PAT(0.001)T(0.001)LHLLQLSGQR 57.325 0.00016757 13122000.0 1157.4 1199.7 2175.4 1827.5 1949.0 4483.7 2285.8 3463.5 5580.2 1823.9 True False 1140.895263758835 1196.9221683593485 1996.5470092868388 1961.9004463612875 1834.3636518814292 4291.9426030151935 2404.1475394947024 3624.426854128385 4951.699113888962 2139.158684806016 0.5333383034472238 0.5595293967019974 0.933332820733629 0.9171364706584155 0.8575163988116073 2.006369435563588 1.123875267679226 1.6943235113280326 2.314788121638575 1.0 11.062827791611623 -6.673950499242359 6.7686571410433025 1.637789418732542 0.7581348849264585 0.5708295178970323 0.3766652683694702 0.163802643795673 10.534510641569831 0.12424486817159172 0.12381342500521658 2.1186025991899796e-07 6.673950499242359 -0.8796545338060834 TVSSDGCST(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVSSDGCSTPSR 12 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 TVSSDGCS(0.042)T(0.941)PS(0.016)R;TVS(0.001)S(0.001)DGCS(0.08)T(0.916)PS(0.003)R 81.676 0.030755 0.0 29382.0 48174.0 39515.0 30272.0 41325.0 25485.0 31543.0 21610.0 30172.0 25963.0 True False 34355.79227904754 52956.39634912538 40457.18746147199 28575.957983148168 33227.662903994686 24148.521736221566 28555.018688456195 21042.76039768765 30613.208420183953 30669.886377005092 1.120179966000982 1.7266577286321385 1.3191176179839055 0.9317268943184981 1.0833970004175595 0.78736912942485 0.9310441629110654 0.6861049349522393 0.9981519997784004 1.0 14.904535201399412 -5.711498576318212 3.6459059243216223 0.9018585222168637 1.4449362114305473 0.6117740683201024 0.17293647131202694 0.13212305605665448 3.5829018985317838 0.046622866071073646 0.08233430465442515 1.9431280616802536e-06 5.711498576318212 0.5430776892136836 TVSSDGCST(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 2 TVSSDGCSTPSR 12 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 TVSSDGCS(0.026)T(0.564)PS(0.41)R;TVS(0.003)S(0.003)DGCS(0.042)T(0.927)PS(0.025)R 87.641 0.020706 2852100.0 24008.0 38059.0 32563.0 26576.0 37974.0 34751.0 38207.0 38461.0 39228.0 33748.0 True False 23665.641517472013 37970.87672383798 29885.795836814992 28530.487694937114 35740.4439797565 33264.780738537615 40185.17151171323 40248.03846878352 34809.729550846954 39581.29683361666 0.5978995993221886 0.95931360923953 0.7550484250792103 0.7208072998433437 0.9029629354994226 0.8404166462349363 1.015256566267523 1.0168448658458453 0.8794489401692068 1.0 15.272531260878225 -6.800745905402451 1.4509566988692955 0.9767245641137684 0.7754157094363365 0.4711574766611647 0.09731855752841019 0.3723597637411289 1.6318477676190708 0.04385931445227056 0.03839057698306944 1.5821734577625948e-07 6.800745905402451 -0.20130885467743187 TVSSDGCSTPSREEGGCSLAS(ph)TPATTLHLLQLSGQR ddPTM_PC-9_AZD4547_30min_R2 1 TVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQR 36 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 T(0.07)VS(0.063)S(0.057)DGCS(0.052)T(0.052)PS(0.052)REEGGCS(0.066)LAS(0.293)T(0.293)PAT(0.001)TLHLLQLSGQR 70.525 2.2494e-06 26594000.0 1699.2 2850.3 6177.0 10011.0 9707.5 7598.5 4783.1 9303.7 3783.5 5642.8 True False 2239.510254444385 3771.603734345578 6095.088944019897 7703.11861840818 8359.78118864718 7123.364593806495 5208.7866339075135 7866.026942757294 3983.4880858316596 5445.247289534649 0.4112779705613284 0.692641405211167 1.1193410730370674 1.4146499155718764 1.5352436251543697 1.3081801826515866 0.956574854537535 1.4445674410187392 0.7315532011718955 1.0 12.410781853399344 -5.152116972013137 2.4431839059701015 1.2283694707617352 0.4309481227404083 0.5490167387672282 0.23672471522785538 0.23012962660649158 2.5002368475580297 0.06407620589115362 0.269023197924651 7.045032938936181e-06 5.152116972013137 -0.7974213480213269 TVSSDGCSTPSREEGGCSLAS(ph)TPATTLHLLQLSGQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQR 36 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 T(0.034)VS(0.031)S(0.088)DGCS(0.113)T(0.113)PS(0.113)REEGGCS(0.113)LAS(0.349)T(0.047)PAT(0.001)TLHLLQLSGQR;T(0.049)VS(0.044)S(0.044)DGCS(0.15)T(0.15)PS(0.15)REEGGCS(0.15)LAS(0.238)T(0.025)PATTLHLLQLSGQR 62.401 4.6589e-05 20874400.0 2256.63 13342.7 16844.6 18561.1 17107.8 16291.1 16243.5 15204.2 9329.0 7880.4 True False 2638.6328885258677 14667.275077167667 17246.23914750124 17521.181742898123 13755.649399369873 15436.766037157511 14704.798087244022 14805.105860181513 9465.418976265957 9309.054138787926 0.2834480119233067 1.575592413417568 1.852630663693483 1.8821656294695743 1.4776634869974998 1.6582529016387735 1.5796232214370431 1.5903985130447629 1.0167970703732947 1.0 13.184418872574694 -8.26709175699706 22.382936628707483 1.008398005736393 1.5241751077730794 0.16484569947539185 0.42495047666949975 199.10729418392404 788392.9985698315 0.3702640930571508 0.1072160575842677 5.40640085363354e-09 8.26709175699706 0.5157771020366864 TVSSDGCSTPSREEGGCSLAS(ph)TPATTLHLLQLSGQR ddPTM_PC-9_Lapatinib_30min_R1 1 TVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQR 36 1 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 T(0.042)VS(0.036)S(0.15)DGCS(0.13)T(0.13)PS(0.13)REEGGCS(0.13)LAS(0.227)T(0.023)PATTLHLLQLSGQR 93.568 7.462200000000001e-14 13356000.0 3715.2 1877.3 8007.5 3714.3 5403.9 6144.3 3863.1 5225.9 8433.7 5516.1 True False 3662.2205667157627 1872.9532271909673 7349.15425984387 3987.462012541575 5086.0532264761705 5881.522612062863 4063.112415706528 5468.7143920859 7483.807895201844 6469.550535258767 0.5660703238589483 0.28950283593635356 1.1359605616790998 0.6163429732575828 0.7861524844357275 0.9091083808695554 0.6280362744772984 0.8453005138891251 1.1567740068518546 1.0 12.659449770747328 -4.352988690109417 0.2819780788234858 0.9896047306352131 6.18011786703238e-25 0.3338152579659871 0.2116610309426183 13.965926348541124 0.7610559342911379 0.25756643196296786 4.985450714821768 4.436201965317137e-05 4.352988690109417 -0.9896047306352131 TVSSPIPYT(ph)PSPS(ph)SSRPISPGLSYASHTVGFTPPTSLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTR 39 1 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 2 T(0.01)VS(0.01)S(0.016)PIPY(0.326)T(0.357)PS(0.158)PS(0.201)S(0.233)S(0.233)RPIS(0.122)PGLS(0.095)Y(0.081)AS(0.09)HT(0.03)VGFT(0.016)PPT(0.007)S(0.007)LT(0.007)R;T(0.003)VS(0.009)S(0.023)PIPY(0.25)T(0.269)PS(0.252)PS(0.174)S(0.173)S(0.173)RPIS(0.168)PGLS(0.203)Y(0.194)AS(0.09)HT(0.013)VGFT(0.004)PPT(0.001)S(0.001)LT(0.001)R 43.38399999999999 0.017431 20695000.0 13656.2 17038.1 23212.8 27407.0 31126.0 21597.1 19372.3 23272.0 20916.2 16340.4 True False 15967.924937755399 18729.529967119866 23766.281187034238 25871.474644692855 25027.083739860576 20464.510056478353 17537.21550069367 22661.134658722214 21222.059855437237 19302.785169464783 0.827234246123983 0.9703019436152792 1.231235854224306 1.3402974968409807 1.2965529854961606 1.0601843141709577 0.9085329058335021 1.17398263824487 1.0994299355830044 1.0 14.236521406331642 -10.377594383582899 14.75649757483028 1.0000000057119176 1.1089513264304631 0.03324425178997692 0.1578361798436241 0.0 0.0 0.16780183746065822 0.0406979235307659 4.1918488691312464e-11 10.377594383582899 0.10895132071854552 TVSSPIPYTPSPSSSRPIS(ph)PGLS(ph)YASHTVGFTPPTSLTR ddPTM_PC-9_Lapatinib_30min_R1 1 TVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTR 39 1 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 2 TVSSPIPY(0.035)T(0.119)PS(0.115)PS(0.115)S(0.261)S(0.261)RPIS(0.422)PGLS(0.424)Y(0.159)AS(0.064)HT(0.012)VGFT(0.006)PPT(0.002)S(0.002)LT(0.002)R 55.35 7.696399999999999e-05 5380200.0 5477.1 5570.0 10149.0 5387.1 6103.5 7385.9 4999.7 6797.9 7531.4 4794.1 True False 5398.995549622876 5557.103007219777 9314.588396272933 5783.285304838787 5744.504129942694 7070.0222743738295 5258.560002280021 7113.755250954048 6683.134422842067 5622.753797263289 0.9602048647854151 0.9883240859531383 1.6565883430298045 1.0285503355408576 1.0216531502301707 1.2573949579323491 0.9352285716012447 1.2651728152167112 1.188587418872028 1.0 12.457061161837151 -5.0377710779828275 24.991715575548177 1.1737479480644681 0.9672329283704031 0.1381939889463809 0.19494994121850165 895.6423227878578 592613.6155613492 0.048874226120079765 0.12937884323945473 9.167035686328064e-06 5.0377710779828275 -0.20651501969406505 TVSSPIPYTPSPSSSRPISPGLS(ph)YASHTVGFTPPTSLTR ddPTM_PC-9_AZD4547_30min_R2 2 TVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTR 39 1 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 TVSSPIPYTPS(0.001)PS(0.001)S(0.009)S(0.009)RPIS(0.361)PGLS(0.458)Y(0.123)AS(0.034)HT(0.004)VGFT(0.001)PPTSLTR;TVSSPIPY(0.006)T(0.007)PS(0.03)PS(0.03)S(0.095)S(0.095)RPIS(0.095)PGLS(0.31)Y(0.278)AS(0.037)HT(0.009)VGFT(0.004)PPT(0.001)S(0.001)LT(0.001)R 76.415 1.1149000000000002e-09 165245000.0 34030.0 23286.7 86540.0 154739.0 109359.0 97485.0 58742.0 105639.0 68902.0 76465.0 True False 44850.83213202827 30813.670378761915 85392.42305576857 119066.31424371825 94176.39052374604 91389.24753928116 63969.924201667396 89314.91989272404 72544.01905377915 73787.98362413456 0.6078338223807822 0.41759740360601727 1.157267333536926 1.6136274281490741 1.276310666022087 1.2385383506995518 0.8669422995419016 1.2104263527199965 0.983141366530735 1.0 16.171098272022448 -5.26855785859999 22.902003672229593 1.1873074597060218 0.5127155674709893 0.6363911446183232 0.19779496309757927 97.65076401908927 314172.11480339465 0.054710436978122126 0.11833241803892826 5.38818056906095e-06 5.26855785859999 -0.6745918922350325 TVSSPIPYTPSPSSSRPISPGLS(ph)YASHTVGFTPPTSLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTR 39 1 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 TVSSPIPY(0.008)T(0.009)PS(0.008)PS(0.008)S(0.025)S(0.025)RPIS(0.085)PGLS(0.333)Y(0.306)AS(0.116)HT(0.042)VGFT(0.02)PPT(0.005)S(0.005)LT(0.005)R;T(0.002)VS(0.004)S(0.008)PIPY(0.004)T(0.005)PS(0.004)PS(0.004)S(0.073)S(0.073)RPIS(0.212)PGLS(0.273)Y(0.241)AS(0.093)HT(0.002)VGFT(0.002)PPTSLTR;TVSS(0.001)PIPY(0.019)T(0.022)PS(0.021)PS(0.021)S(0.059)S(0.059)RPIS(0.093)PGLS(0.268)Y(0.245)AS(0.093)HT(0.017)VGFT(0.019)PPT(0.02)S(0.02)LT(0.02)R 57.397 5.6597e-05 154272000.0 17744.9 15073.5 44398.4 52582.7 61666.0 59499.4 47306.6 42274.7 46615.9 30672.8 True False 20748.76109224936 16569.89746270895 45457.026237869664 49636.66179441351 49582.989973084936 56379.14672129255 42825.376377875335 41165.03391874713 47297.56934888157 36233.53583424882 0.5726397000603272 0.45730832173013264 1.2545567301467326 1.3699094126909837 1.3684281379521865 1.5559935132800815 1.1819265051520518 1.1361031423225592 1.3053534042398025 1.0 15.145037976994866 -5.26890210093331 14.1157480512326 1.2903444749212714 0.5149474065674071 0.8122756729825867 0.14525785307524183 0.561410735758597 1064.266018982251 0.038611072523573764 0.0852374080900354 5.383911334691117e-06 5.26890210093331 -0.7753970683538642 TVSSPIPYTPSPSSSRPISPGLS(ph)YASHTVGFTPPTSLTR ddPTM_PC-9_Lapatinib_30min_R1 3 TVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTR 39 1 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 TVSSPIPYTPSPSS(0.001)S(0.001)RPIS(0.084)PGLS(0.41)Y(0.367)AS(0.128)HT(0.007)VGFT(0.001)PPTSLTR;TVSSPIPY(0.002)T(0.002)PS(0.006)PS(0.005)S(0.016)S(0.016)RPIS(0.084)PGLS(0.321)Y(0.282)AS(0.187)HT(0.05)VGFT(0.018)PPT(0.005)S(0.005)LT(0.002)R;TVSSPIPYT(0.002)PS(0.005)PS(0.005)S(0.017)S(0.017)RPIS(0.266)PGLS(0.371)Y(0.314)AS(0.002)HTVGFTPPTSLTR 95.361 3.8307e-20 77567000.0 54897.0 31733.7 89029.0 49886.0 70959.0 78697.0 52569.0 64053.0 91624.0 45533.7 True False 54114.158713123135 31660.222567362714 81709.37928187817 53554.78285481762 66785.33113076161 75331.31276166708 55290.76559790752 67029.1362169728 81304.34027650655 53404.13937515855 1.0132952116871836 0.5928421080799173 1.5300195872061197 1.0028208202851245 1.2505646924033655 1.4105893970591383 1.035327340629827 1.255129976837564 1.5224351750217708 1.0 15.704663949637695 -5.255886896721634 24.99991186091128 1.2491104718414507 0.8030686637796315 0.42359166484858723 0.2089350372952974 401.8732340259494 1809410.301411042 0.05050445059249248 0.12592200302519585 5.5477017289951195e-06 5.255886896721634 -0.44604180806181926 TVSSPIPYTPSPSSSRPISPGLSY(ph)AS(ph)HTVGFTPPTSLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTR 39 1 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 2 T(0.002)VS(0.004)S(0.01)PIPY(0.036)T(0.039)PS(0.042)PS(0.042)S(0.097)S(0.097)RPIS(0.202)PGLS(0.215)Y(0.363)AS(0.378)HT(0.194)VGFT(0.176)PPT(0.034)S(0.034)LT(0.034)R 45.336000000000006 0.0024302 9968200.0 0.0 1738.8 2642.1 7342.9 12953.0 12919.0 11751.0 13149.0 9619.0 10967.0 True False 0.0 1911.4165726711326 2705.097684220048 6931.501119003003 10414.952633888523 12241.504897400291 10637.860210127412 12803.852682517107 9759.65967763985 12955.230285275775 0.0 0.14754014637960908 0.20880351986444565 0.535034960118075 0.803918757486357 0.9449083210287149 0.8211247485286184 0.9883153290659205 0.7533374137495772 1.0 13.661247039874292 -5.917148705888343 1.3983958791264886 0.9027827939766468 0.05142514785401437 0.9546628952251013 0.07562879387181705 0.0753559664250149 0.29916488081831943 0.02480331912234199 0.04891021039857583 1.2101836860701949e-06 5.917148705888343 -0.8513576461226324 down TVSSPPT(ph)SPRPGSAATVSASTSNIIPPR ddPTM_PC-9_AZD4547_30min_R2 1 TVSSPPTSPRPGSAATVSASTSNIIPPR 28 1 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 1 T(0.043)VS(0.043)S(0.106)PPT(0.554)S(0.19)PRPGS(0.026)AAT(0.003)VS(0.002)AS(0.005)T(0.014)S(0.014)NIIPPR 44.303999999999995 0.025322 89815000.0 13004.0 14097.0 22597.0 27132.0 21804.0 23118.0 16025.0 17035.0 15815.0 19503.0 True False 17139.00149999692 18653.579568140063 22297.349015382482 20877.13658522135 18776.89096443606 21672.427805437732 17451.193955461495 14402.632175357166 16650.948613037595 18820.20590625119 0.9106702437460659 0.9911464125875593 1.1847558483925167 1.1092937393573863 0.9976984873581674 1.1515510464335126 0.927258396767329 0.7652749522030089 0.8847378554719707 1.0 14.199994791797751 -7.468613800347583 6.486457621284642 0.8641673813073795 1.0590186927133913 0.4274685365685169 0.09272727588940376 0.19592514077586562 18.610297764141045 0.0403455801857362 0.026604190776235145 3.399274212565829e-08 7.468613800347583 0.19485131140601186 TVSSPPT(ph)SPRPGSAATVSASTSNIIPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVSSPPTSPRPGSAATVSASTSNIIPPR 28 1 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 1 T(0.089)VS(0.099)S(0.261)PPT(0.393)S(0.133)PRPGS(0.018)AAT(0.001)VS(0.001)AS(0.001)T(0.002)S(0.002)NIIPPR 42.166000000000004 0.042979 26840000.0 9885.3 9647.9 8043.8 8780.6 9718.6 8411.1 9925.4 10103.0 8217.5 6722.3 True False 11558.686046425322 10605.679751250187 8235.594698281373 8288.651449089293 7814.310095553841 7970.0071091046975 8985.194258326834 9837.806955013342 8337.66539151736 7940.999776302478 1.4555706298996178 1.3355597594775968 1.0370979637674875 1.0437793329026752 0.9840461296666065 1.0036528565192488 1.131494082790487 1.2388625150665933 1.0499515963214872 1.0 12.955104939575916 -5.132857707933856 3.39665541765801 1.0663964648581339 1.4371111717736 0.778119596680568 0.07247052532732921 0.12222450701802604 2.5355665919284993 0.02119569436931177 0.07187422478563495 7.36448347605961e-06 5.132857707933856 0.37071470691546615 TVSSPPTS(ph)PRPGSAATVSASTSNIIPPR ddPTM_PC-9_AZD4547_30min_R2 1 TVSSPPTSPRPGSAATVSASTSNIIPPR 28 1 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 1 T(0.007)VS(0.022)S(0.078)PPT(0.078)S(0.773)PRPGS(0.006)AAT(0.003)VS(0.004)AS(0.005)T(0.012)S(0.012)NIIPPR 75.17699999999999 1.3865999999999999e-05 46691000.0 9976.4 11943.0 15583.0 30554.0 27410.0 25027.0 22614.0 23246.0 16314.0 15251.0 True False 13148.687677989034 15803.341191905834 15376.35923824868 23510.247354594318 23604.594631039836 23462.05773365731 24626.60219087715 19653.864839938535 17176.324734308902 14717.067132043123 0.8934312495837371 1.073810498390511 1.0447977915905606 1.5974818313769876 1.603892570391699 1.5942074275501488 1.6733362680162158 1.3354471148090803 1.16710242470195 1.0 13.84520257433864 -5.717173724087852 8.318631925429651 1.4632224697315026 1.0084854912370318 0.45261556219055243 0.2089041547994161 0.22561400546582486 37.697492262970705 0.05760036269282515 0.09934217758474259 1.9179013988471114e-06 5.717173724087852 -0.4547369784944708 TVSSPPTS(ph)PRPGSAATVSASTSNIIPPR ddPTM_PC-9_Lapatinib_30min_R1 1 TVSSPPTSPRPGSAATVSASTSNIIPPR 28 1 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 1 T(0.006)VS(0.015)S(0.033)PPT(0.209)S(0.558)PRPGS(0.025)AAT(0.053)VS(0.011)AS(0.032)T(0.032)S(0.027)NIIPPR 51.475 0.0057594 56090000.0 10120.0 8967.1 9615.8 8548.0 8283.8 10440.0 9300.0 7466.5 9480.4 6988.3 True False 9975.68694421929 8946.337230886978 8825.226042061411 9176.648435292082 7796.563170577419 9993.505536828654 9781.508494750518 7813.420847798345 8412.617518962204 8196.218343675573 1.217108491493129 1.0915201201039524 1.0767436483523158 1.1196198112966371 0.9512390768107662 1.2192824931927193 1.1934172669153207 0.9532958396389469 1.0264023194859873 1.0 13.000742702288717 -1.5228787454037322 0.07602471929518063 0.898283261314478 1.5548288203171605 0.20702888718969326 0.08653999191353841 404.0223858264267 2.2597243763099986 3.123180592639631 28.038602113928835 0.029999999991476196 1.5228787454037322 0.6565455590026825 TVSSPPTSPRPGSAATVSAST(ph)SNIIPPR ddPTM_PC-9_AZD4547_30min_R2 1 TVSSPPTSPRPGSAATVSASTSNIIPPR 28 1 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 1 T(0.002)VS(0.001)S(0.003)PPT(0.001)S(0.003)PRPGS(0.012)AAT(0.004)VS(0.008)AS(0.021)T(0.472)S(0.472)NIIPPR 46.92 0.019295 45476000.0 6565.8 7391.8 7774.4 6616.3 11115.0 6941.4 2942.3 7805.0 7802.7 5670.9 True False 8653.58782287603 9781.054795472633 7671.306376297283 5091.0142558160105 9571.874108865653 6507.353160682816 3204.159000009633 6598.916591057398 8215.134792472243 5472.363517087621 1.5813254722305892 1.7873547261491296 1.4018268984403899 0.9303136094521433 1.7491298008579266 1.1891302798806052 0.5855164756516172 1.2058622513749462 1.5012041445748687 1.0 12.417948353131578 -5.388667694350741 0.8511280044127874 1.1344503520444316 1.8140313343227736 0.28125846805169397 0.3088397950302089 1.5770758095524324 1.584849089783432 0.13157175104016444 0.8524605254678295 4.086319363854509e-06 5.388667694350741 0.6795809822783421 TVSSSNGGES(ph)SSR ddPTM_PC-9_Lapatinib_30min_R1 1 TVSSSNGGESSSR 13 0 Q8WW12;Q8WW12-2 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 1 T(0.006)VS(0.283)S(0.009)S(0.067)NGGES(0.622)S(0.014)SR 116.79 0.00026868 2747800.0 3027.6 4285.4 4299.1 3946.6 5807.5 4944.0 6197.4 6988.2 6065.8 5434.6 True False 2984.4258688061586 4275.477419594194 3945.644593005907 4236.846129471656 5465.914267984301 4732.556645026903 6518.271047888907 7312.897283678354 5382.605728294265 6373.96336885069 0.46822137124146823 0.6707721981096227 0.6190253010062967 0.6647114023555513 0.8575377597392558 0.7424825608748746 1.022640180165365 1.1473077048757758 0.8444676281948604 1.0 12.63797501263739 -6.523088473128027 0.7749100222793208 1.0223544192972216 0.5560354293076475 0.7501114915871514 0.09953696441239025 0.3278815485633296 0.4376785907541372 0.06216694244077886 0.078662072182394 2.998551601108778e-07 6.523088473128027 -0.4663189899895741 TVST(ph)SSTSGNDFEETK ddPTM_PC-9_Lapatinib_30min_R1 1 TVSTSSTSGNDFEETK 16 0 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 T(0.005)VS(0.251)T(0.744)SSTSGNDFEETK 226.06 2.7200999999999996e-28 6785500.0 7225.9 12005.0 10373.0 10952.0 37676.0 48262.0 47775.0 44702.0 53025.0 49996.0 True False 7122.85734093223 11977.203160084999 9520.171980937937 11757.446614800996 35459.971753865946 46197.946764216904 50248.55573512968 46779.018112674166 47052.76612199597 58637.74198451751 0.12147223102166728 0.20425757805011344 0.16235570570660118 0.20050988010256923 0.6047294891271335 0.7878534404755019 0.8569319696586735 0.7977629514626522 0.8024314124240938 1.0 15.839541928954663 -6.419420724223276 2.0018333746970858 0.8438379654777698 0.15796118325239028 0.9673035354160324 0.058782983898052206 0.052480869620846984 0.41648659198638793 0.02042440488557339 0.023750644334147558 3.806968433645736e-07 6.419420724223276 -0.6858767822253795 down TVSYNGILGPECGTK ddPTM_PC-9_Lapatinib_30min_R1 1 TVSYNGILGPECGTK 15 0 P21980;P21980-2 P21980 TGM2 Protein-glutamine gamma-glutamyltransferase 2 0 124.3 0.00093442 0.0 7057.4 8409.0 7470.2 6528.6 5666.1 6624.7 6222.0 6571.2 8452.0 6620.0 False True 6956.760181831349 8389.529477147424 6856.028991805893 7008.735022771162 5332.831137981208 6341.377023929962 6544.144715520185 6876.521941345006 7500.0467564943 7764.258179404468 0.8959980491484564 1.0805320074751708 0.8830243448102034 0.9026921646375164 0.6868436127133326 0.8167395876596618 0.8428551143339404 0.8856637404956113 0.965970809212525 1.0 12.922632376432572 -5.438667467428068 7.035861617897216 0.8582978035041307 0.9883462822066279 0.19559848457610485 0.09099595200353292 0.3558431241727976 25.510127084955993 0.024096464720293993 0.05040906011467335 3.6419378694933783e-06 5.438667467428068 0.13004847870249725 TVT(ph)NAVVTVPAYFNDS(ph)QRQAT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 TVTNAVVTVPAYFNDSQRQATK 22 1 P11142;P11142-2;E9PN89;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65 P11142 HSPA8 Heat shock cognate 71 kDa protein 3 T(0.201)VT(0.74)NAVVT(0.058)VPAY(0.001)FNDS(0.999)QRQAT(1)K 54.17100000000001 0.036577 0.0 2512.5 1147.0 2570.5 1288.7 1246.5 2246.3 1106.3 2378.7 2201.0 1159.6 True False 2476.67128926393 1144.3441919714692 2359.163412416945 1383.475296977176 1173.1833207132906 2150.2309853810534 1163.5788008325264 2489.2230858712815 1953.100202442494 1360.035314930124 1.8210345437913693 0.8414077042038157 1.7346339367210875 1.0172348333824377 0.8626123953064899 1.5810111412375554 0.8555504317123624 1.8302635663539168 1.4360657999111153 1.0 10.409428397912027 -7.765357872983511 24.999997101772404 1.4748733201810658 1.237590596436019 0.03564377389035278 0.3938008107298253 289.63715718173904 1847830.366736522 0.1923670334400136 0.09785130283801069 1.7164933570565348e-08 7.765357872983511 -0.23728272374504678 TVT(ph)NAVVTVPAYFNDSQR ddPTM_PC-9_AZD4547_30min_R2 2 TVTNAVVTVPAYFNDSQR 18 0 P11142;P11142-2;E9PN89;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65 P11142 HSPA8 Heat shock cognate 71 kDa protein 1 T(0.015)VT(0.968)NAVVT(0.017)VPAYFNDSQR;T(0.005)VT(0.995)NAVVTVPAYFNDSQR 178.71 3.2302e-08 7599100.0 29539.8 35159.0 40978.0 60027.0 39584.0 40624.0 34986.9 44359.0 29664.6 34466.0 True False 38932.84193399024 46523.45917828163 40434.604945450454 46188.70255790511 34088.4448695761 38083.774858037126 38100.666321393845 37504.33581841318 31232.61019451882 33259.35583063393 1.1705831625918224 1.398808185437874 1.2157362623423895 1.388743149239302 1.024927994491659 1.1450544938985139 1.1455623649301339 1.1276326579924123 0.9390623905515225 1.0 15.021472606233873 -6.928654410827537 0.537162169304279 0.993041778337205 1.313249262630734 0.5241489392975243 0.099131662761365 0.7477560474395512 0.4621569551991113 0.08732901395337912 0.093775639164101 1.1785434246186966e-07 6.928654410827537 0.32020748429352897 TVT(ph)NAVVTVPAYFNDSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVTNAVVTVPAYFNDSQR 18 0 P11142;P11142-2;E9PN89;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65 P11142 HSPA8 Heat shock cognate 71 kDa protein 1 T(0.005)VT(0.844)NAVVT(0.151)VPAYFNDSQR;T(0.012)VT(0.988)NAVVTVPAYFNDSQR 143.39 6.8476e-09 2352800.0 14290.6 15143.900000000001 13916.099999999999 12324.5 15156.099999999999 17660.1 16780.7 13180.8 15290.4 13599.8 True False 16709.71632778425 16647.286309451563 14247.91260110315 11633.99822156811 12186.371003974195 16733.973267170735 15191.110614252837 12834.817966211998 15513.99317340518 16065.336084042428 1.0401099759364436 1.0362239683231516 0.8868729870678205 0.7241677460531977 0.7585506422164937 1.041619868991876 0.9455831197544661 0.7989137543758404 0.965681209048288 1.0 13.971663541604316 -5.265381147450302 6.586142765589691 0.8795104721679475 1.0391159240138665 0.25882598474374474 0.09892729800630005 0.17324511696591893 44.189667665091655 0.02710232987928761 0.06349882170773707 5.42773770877154e-06 5.265381147450302 0.159605451845919 TVT(ph)PASSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TVTPASSAK 9 0 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 1 T(0.325)VT(0.674)PAS(0.001)SAK 99.34299999999999 0.0102 129500000.0 891920.0 1260200.0 1113500.0 1309900.0 1214000.0 1041600.0 1109100.0 1015500.0 888300.0 716220.0 True False 1042904.4397770108 1385304.3276283448 1140050.0629722655 1236510.5497531013 976125.4147719191 986976.6623679957 1004038.0188113599 988844.2010111891 901289.7070015066 846065.0164056002 1.23265283347568 1.6373497317187682 1.3474733511800587 1.4614840772004252 1.1537238815509285 1.1665494296892698 1.1867149679310556 1.1687567525391467 1.0652723957675516 1.0 19.69040900686221 -6.274006051864838 11.489194670527906 1.1372051977493691 1.4301354435394522 0.6385560403740937 0.10878100002549272 0.4068193287949124 369.08471443877926 0.0314420282414311 0.036620785805101475 5.321008444251109e-07 6.274006051864838 0.2929302457900831 TVTCVTVVEPEAPPS(ph)PDVLQAATHR ddPTM_PC-9_AZD4547_30min_R2 4 TVTCVTVVEPEAPPSPDVLQAATHR 25 0 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 TVTCVTVVEPEAPPS(0.999)PDVLQAAT(0.001)HR;TVTCVTVVEPEAPPS(0.999)PDVLQAAT(0.001)HR;TVTCVTVVEPEAPPS(1)PDVLQAATHR;TVTCVTVVEPEAPPS(1)PDVLQAATHR 211.35 1.3375e-31 206252000.0 58328.5 56764.9 77486.0 100766.0 85622.9 75524.6 65537.7 86164.4 64380.9 74219.6 True False 76875.74969183099 75113.04382687891 76458.48501154696 77535.95551918086 73735.63829383645 70802.03482284643 71370.42833665221 72849.67184093589 67783.94293778768 71621.19439468789 1.0733659266862607 1.0487544149703543 1.0675399322468972 1.0825839498277297 1.0295226003562068 0.9885626094515088 0.9964987171722695 1.017152428923178 0.9464229619551721 1.0 16.128098957589692 -6.546492444411038 3.253900378007882 0.9912898843877795 1.0664014154562589 0.7957599447659018 0.01866116072510715 0.110107363009168 2.42637978069359 0.006260397823036394 0.006552853585241781 2.8412376146622236e-07 6.546492444411038 0.07511153106847934 TVTCVTVVEPEAPPS(ph)PDVLQAATHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 TVTCVTVVEPEAPPSPDVLQAATHR 25 0 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 TVTCVTVVEPEAPPS(0.999)PDVLQAAT(0.001)HR;TVTCVTVVEPEAPPS(1)PDVLQAATHR;TVTCVTVVEPEAPPS(0.999)PDVLQAAT(0.001)HR;TVTCVTVVEPEAPPS(1)PDVLQAATHR 188.73 3.0196e-21 138574000.0 73883.0 73780.0 89409.0 91537.0 98028.0 87771.0 89957.0 86415.0 84380.0 64973.0 True False 86389.93264423343 81104.39080496659 91540.84964552052 86408.47865695815 78820.11709988602 83168.1342479851 81435.62172771952 84146.69781426094 85613.89786872361 76752.09057401495 1.1255710691153662 1.0567059502666518 1.1926821661912155 1.125812704393129 1.0269442370938 1.0835943832407133 1.0610215450638192 1.0963440498485848 1.1154601422375965 1.0 16.227918426705724 -6.2252631576355135 23.599747036369152 1.0695526534001738 1.1251217362778423 0.3172527076059183 0.043582206000152356 415.4570095757842 271024.73423729104 0.012798076177648483 0.01652161786666972 5.953013156445113e-07 6.2252631576355135 0.055569082877668485 TVTCVTVVEPEAPPS(ph)PDVLQAATHR ddPTM_PC-9_Lapatinib_30min_R1 4 TVTCVTVVEPEAPPSPDVLQAATHR 25 0 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 TVTCVTVVEPEAPPS(1)PDVLQAATHR;TVTCVTVVEPEAPPS(1)PDVLQAATHR;TVTCVTVVEPEAPPS(1)PDVLQAATHR;TVTCVTVVEPEAPPS(1)PDVLQAATHR 187.45 3.9127e-21 186211000.0 100861.0 124846.0 128733.0 106840.0 128544.0 121317.0 106763.0 101537.0 120195.0 88633.0 True False 99422.70364435803 124556.92675751513 118149.06966375042 114697.37000779172 120983.29464722748 116128.5547137396 112290.66574462905 106254.7796990426 106657.37339053872 103953.09595395093 0.9564188803804383 1.1982031474338317 1.1365613364328082 1.1033569414671427 1.1638257960188176 1.1171245420644533 1.0802051128363843 1.022141560325546 1.0260144001654912 1.0 16.665573199933718 -7.6232036919693185 2.279263381228891 1.014126257447548 1.1194188734195187 0.340051671408628 0.0597270855242439 0.3352157929905927 3.4840736700633625 0.0349418471360434 0.016947521324357832 2.381202380414303e-08 7.6232036919693185 0.1052926159719707 TVTLELLDNGAGADAT(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 TVTLELLDNGAGADATK 17 0 A8K7I4 A8K7I4 CLCA1 Calcium-activated chloride channel regulator 1 1 TVTLELLDNGAGADAT(1)K 141.34 0.00023955 7296400.0 17322.0 14370.0 25140.0 28857.0 26467.0 22945.0 18221.0 23855.0 18864.0 27152.0 True False 22830.03568001745 19014.821479334092 24806.6271738158 22204.46448620566 22792.51390367498 21510.245522786085 19842.633701245803 20168.75788336633 19861.11252838072 26201.416744425584 0.8713282912411443 0.7257173024195168 0.9467666353993424 0.8474528191659604 0.8698962398101676 0.8209573448871784 0.7573114803216652 0.7697582951371239 0.758016740930859 1.0 14.677357201804428 -6.984663168995374 9.77075425598105 0.8002363443982363 0.8497545503650665 0.008559341272561749 0.08374520008942651 0.7208832849634274 423.28190728220886 0.028485422473447864 0.02480242486621253 1.0359453157768834e-07 6.984663168995374 0.04951820596683021 TVTLELLDNGAGADAT(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVTLELLDNGAGADATK 17 0 A8K7I4 A8K7I4 CLCA1 Calcium-activated chloride channel regulator 1 1 TVTLELLDNGAGADAT(1)K;TVTLELLDNGAGADAT(1)K 140.03 6.6224e-05 14904300.0 85549.0 90157.0 90374.0 103706.0 103780.0 103688.0 93180.0 96695.0 90745.0 94931.0 True False 100030.75603023055 99107.19113314434 92528.8589053038 97895.68903938828 83445.05399096348 98250.41874770813 84353.31583522035 94156.85870682144 92071.97395232669 112141.23882661755 0.892006875230698 0.8837711458348944 0.8251100119231195 0.8729677865494742 0.7441067609390203 0.8761310270489687 0.7522060280218561 0.8396274171038729 0.821035819790433 1.0 16.774957386924086 -5.222826998229256 5.478857807802069 0.8313317680717294 0.8891744428233281 0.0541650643390954 0.0680456152076278 0.439446632205985 35.58167541198827 0.01608911205781122 0.04295499711106472 5.986500205815806e-06 5.222826998229256 0.057842674751598766 TVTLELLDNGAGADAT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 2 TVTLELLDNGAGADATK 17 0 A8K7I4 A8K7I4 CLCA1 Calcium-activated chloride channel regulator 1 1 TVTLELLDNGAGADAT(1)K;TVTLELLDNGAGADAT(1)K 122.33 0.00014614 15818400.0 101127.0 80570.0 90100.0 80260.0 85315.0 82875.0 71678.0 67207.0 91039.0 65177.0 True False 99684.91043557931 80383.44511520588 82692.32579605792 86162.58813951141 80296.93943574362 79330.6294410607 75389.1361168524 70329.68257121605 80785.22913682974 76442.75760710644 1.3040464990539822 1.0515508287698545 1.0817548762575055 1.1271517516723046 1.050419188805911 1.0377782267981106 0.9862168565965485 0.9200306840406017 1.0568068403816926 1.0 16.222092202793363 -1.5228787452803376 0.4503318534164573 0.997359430748022 6.781018241842483 0.6747943135340309 0.05523629930633952 56.006606628524224 0.6741366173551433 0.035800089554238614 297.9108331829333 0.029999999999999995 1.5228787452803376 5.783658811094462 TVTNAVVT(ph)VPAYFNDSQR ddPTM_PC-9_Lapatinib_30min_R1 1 TVTNAVVTVPAYFNDSQR 18 0 P11142;P11142-2;E9PN89;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65 P11142 HSPA8 Heat shock cognate 71 kDa protein 1 T(0.054)VT(0.247)NAVVT(0.699)VPAYFNDSQR 129.29 0.00010275 3082100.0 10392.0 9202.9 10487.0 8421.4 9021.5 9351.7 10898.0 9478.8 8071.5 5998.3 True False 10243.808174340596 9181.591250474494 9624.79934099066 9040.737848966864 8490.873106951425 8951.74959087744 11462.245115676473 9919.219652060669 7162.4026733369265 7035.0981627676465 1.4561002472651534 1.3051120308550754 1.368111591097431 1.2850905047514203 1.206930295854048 1.2724413197606006 1.6292942686057934 1.4099617976273402 1.0180956267594137 1.0 12.7803548386072 -8.2671909373045 24.504523046872475 1.0090477057979117 1.3622035423770547 0.6224311772628882 0.11135817622238266 270.8280967007063 1153839.823360024 0.10534805987035638 0.030237245859712866 5.4051663289076905e-09 8.2671909373045 0.35315583657914296 TVTNAVVTVPAYFNDSQR ddPTM_PC-9_AZD4547_30min_R2 2 TVTNAVVTVPAYFNDSQR 18 0 P11142;P11142-2;E9PN89;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 ; 238.67 7.1186e-43 9260500.0 38453.0 29369.9 43976.0 57641.0 52290.0 45142.0 40065.0 49983.0 33727.0 40339.0 False True 50680.25412791311 38863.1458153023 43392.84950659205 44352.75799457256 45030.43609110077 42319.2636038182 43630.707383810615 42259.275845076474 35509.74036496485 38926.74388823602 1.3019392085149226 0.9983662113349032 1.1147310350739539 1.1393903924231465 1.1567994543902587 1.0871513868543068 1.1208414325400633 1.0856103445592213 0.9122196417691175 1.0 15.248474051931577 -8.120220235564283 4.325954692122675 0.9581196301819528 1.1240355743355563 0.4644771548996117 0.0737202537253494 0.19883921678941094 5.895975615414715 0.05117514814107943 0.0179769443788857 7.581929894220556e-09 8.120220235564283 0.16591594415360356 TVTNAVVTVPAYFNDSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TVTNAVVTVPAYFNDSQR 18 0 P11142;P11142-2;E9PN89;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 ; 188.92 3.3864e-10 11703800.0 39938.0 44166.0 50812.0 51973.0 58252.0 54586.0 52349.0 50580.0 49994.0 42587.0 False True 46698.714588544055 48550.50859707456 52023.55078558311 49061.12130873947 46837.93876548086 51723.41406683895 47390.12374606076 49252.32859393988 50725.06767064424 50307.685981493465 0.9282620275105273 0.9650713931651455 1.0341074086516493 0.9752211884042418 0.9310294809169117 1.02814138749825 0.942005636345389 0.9790219453158346 1.0082965789621952 1.0 15.618491210599977 -4.875661783901953 4.181244824366103 0.9847254071970798 0.9285333771577716 0.24241376790821012 0.03162687546261334 0.3159178582656858 9.01748674202987 0.007812031173755616 0.041442760738280286 1.3314909413103526e-05 4.875661783901953 -0.05619203003930817 TVTNAVVTVPAYFNDSQR ddPTM_PC-9_Lapatinib_30min_R1 2 TVTNAVVTVPAYFNDSQR 18 0 P11142;P11142-2;E9PN89;E9PLF4;E9PQQ4;E9PQK7;E9PK54;E9PI65 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 ; 166.79 5.6593e-07 43127000.0 34480.0 27850.7 30661.4 28565.7 32641.9 38901.0 32068.2 29322.0 29181.3 28669.0 False True 33988.30887714241 27786.213415291924 28140.538048426733 30666.516870381725 30721.967618444578 37237.294912660094 33728.53448509232 30684.407165223754 25894.594701288104 33624.398450958746 1.010822808524424 0.8263705730176311 0.8369082970947351 0.912031687796851 0.9136808101787347 1.107448657169905 1.0030970378335677 0.9125637506936228 0.770113247945697 1.0 15.037220837268327 -4.455720969454561 19.699267947381763 0.9226341863810316 2.8664620165910923 0.0779042671183755 0.09316027392051318 284.1578778601049 98020.46138758631 0.02415285056302631 4209.038274124029 3.5017007609303365e-05 4.455720969454561 1.943827830210061 TVVLT(ph)PTYSGEADALLPSLR ddPTM_PC-9_AZD4547_30min_R2 2 TVVLTPTYSGEADALLPSLR 20 0 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 1 TVVLT(0.995)PT(0.004)YS(0.001)GEADALLPSLR;TVVLT(0.971)PT(0.028)YS(0.001)GEADALLPSLR 169.72 5.7404e-08 6459100.0 42208.0 47960.0 63022.0 103412.0 84982.0 73240.0 63225.0 79111.0 67618.0 72042.0 True False 55629.26601906106 63462.13209108303 62186.28710215672 79571.9610994733 73183.71619609724 68660.2912220026 68851.90251694575 66886.21273992855 71192.14943511701 69519.83150787806 0.8001927624458799 0.912863721251848 0.8945114761262001 1.1445936990002072 1.0527027268154985 0.987636041871332 0.9903922524487617 0.9621170145147567 1.0240552643895497 1.0 16.08513696511023 -5.579212480587179 12.043695193988444 1.0199364833424716 0.8682979251066691 0.6352057668399066 0.05376941239038591 0.5016773340919987 106.02654036941428 0.015449303967459126 0.02676788975064197 2.635041863959821e-06 5.579212480587179 -0.1516385582358024 TVVLT(ph)PTYSGEADALLPSLR ddPTM_PC-9_Lapatinib_30min_R1 1 TVVLTPTYSGEADALLPSLR 20 0 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 1 T(0.002)VVLT(0.761)PT(0.235)YS(0.001)GEADALLPSLR 100.07 0.00080863 2517200.0 13349.0 10158.0 13657.0 11617.0 19119.0 15850.0 17044.0 12777.0 16950.0 12918.0 True False 13158.640812093217 10134.479775105661 12534.174177544526 12471.352933175964 17994.458009400245 15172.132448154623 17926.45492306752 13370.66606473173 15040.91250858713 15150.859087846971 0.8685079001657549 0.668904628862589 0.8272913175991863 0.8231449359316969 1.187685655649337 1.0014041025782305 1.1831972576028345 0.8825021727947298 0.9927432115484439 1.0 13.887111979626383 -6.1176547920024715 6.304990084084442 1.039973750727342 0.784091921372154 0.6025254533442959 0.09742294776811238 0.161909959734991 7.78196090049607 0.028723299313659266 0.03735946472175932 7.626850051814782e-07 6.1176547920024715 -0.2558818293551881 TVYS(ph)ILR ddPTM_PC-9_Lapatinib_30min_R1 1 TVYSILR 7 0 P05198;H0YJS4;G3V4T5 P05198 EIF2S1 Eukaryotic translation initiation factor 2 subunit 1 1 T(0.003)VYS(0.997)ILR 80.165 0.025804 1624100.0 8254.5 8252.5 11961.0 8926.2 7583.0 10779.0 8267.7 8418.9 8432.7 8575.3 True False 8136.789316310093 8233.391843282085 10977.612750795197 9582.6625249303 7136.982848751607 10318.007297076254 8695.761051833208 8810.072828705488 7482.920525732306 10057.529179130992 0.8090246790626903 0.8186296750066681 1.0914820683367585 0.9527849588360108 0.7096159227219134 1.0258988180204085 0.8646021201585571 0.87596791138186 0.7440118136827377 1.0 13.295988303098527 -7.485480597587734 24.926375085679254 0.8600507081503196 0.9035550682404201 0.011804831111661085 0.11822564372523454 2575.775313870686 1716793.0779165723 0.050068857634871435 0.03374628719011827 3.269786545099914e-08 7.485480597587734 0.0435043600901005 TWS(ph)PTACGGK ddPTM_PC-9_Lapatinib_30min_R1 1 TWSPTACGGK 10 0 Q15464;Q15464-2 Q15464 SHB SH2 domain-containing adapter protein B 1 T(0.033)WS(0.952)PT(0.015)ACGGK 83.869 0.012953999999999999 5426900.0 23204.0 50551.0 33970.0 31442.0 34529.0 29342.0 25374.0 26222.0 21880.0 23301.0 True False 22873.106704907557 50433.952265344175 31177.11772799207 33754.34956743725 32498.072106625903 28087.11105954276 26687.741564064476 27440.369848117374 19415.64399338562 27328.54680336913 0.8369675442123291 1.8454677677602147 1.140826036317031 1.2351315205415876 1.1891620999993846 1.027757211593853 0.976551799701781 1.0040918035471413 0.7104528511187435 1.0 14.738121126080417 -6.758455235180907 0.9230649562534944 0.8904594942433187 1.326855497407146 0.2919074765984422 0.24447581030574903 0.6528522454764139 1.2034365028147214 0.1412287678061336 0.13066819898292908 1.7439931099516653e-07 6.758455235180907 0.4363960031638273 TWT(ph)LCGTPEYLAPEIILSK ddPTM_PC-9_AZD4547_30min_R2 2 TWTLCGTPEYLAPEIILSK 19 0 B1APG2;Q15136;B1APF8;B1APF9;K7ERP6;B1APG3;A0A087WVC4;A0A0A0MS54;P22694;P22694-9;P22694-6;P22694-7;P22694-5;P22694-3;P22612;P17612;P17612-2;P22694-4;P22694-10;P22694-8;P22694-2 B1APG2 PRKACB;KIN27;PRKACA;PRKACG cAMP-dependent protein kinase catalytic subunit beta;cAMP-dependent protein kinase catalytic subunit gamma;cAMP-dependent protein kinase catalytic subunit alpha 1 T(0.187)WT(0.812)LCGTPEYLAPEIILSK;T(0.453)WT(0.544)LCGT(0.004)PEYLAPEIILSK 114.92 0.00016089 20869800.0 41666.0 41540.0 56971.0 60296.0 44387.0 41467.0 53827.0 37677.0 40337.0 42214.0 True False 54914.92129336146 54966.992641025616 56215.52731580987 46395.688763913706 38224.63122539092 38874.061934773184 58617.49872328405 31854.885381328575 42469.13147038239 40736.100708941616 1.3480652379010734 1.3493434983815302 1.3799928401951957 1.1389329846616814 0.9383478182780655 0.9542902059410976 1.438957035728691 0.7819817023953988 1.0425428730605129 1.0 15.314020270577297 -5.892419556283715 3.8134685081648296 1.0322564101100562 1.3582598290188312 0.4728074272467585 0.156813119889216 0.2050817369424199 5.62947798791404 0.04562546574045172 0.0706309729229291 1.2810923673808127e-06 5.892419556283715 0.32600341890877504 TWTTPEVT(ph)SPPPSPR ddPTM_PC-9_AZD4547_30min_R2 3 TWTTPEVTSPPPSPR 15 0 Q5T1S5;Q7Z6M1-2;Q7Z6M1 Q5T1S5 RABEPK Rab9 effector protein with kelch motifs 1 TWTT(0.005)PEVT(0.622)S(0.307)PPPS(0.067)PR;TWTT(0.006)PEVT(0.589)S(0.377)PPPS(0.028)PR;TWTT(0.005)PEVT(0.707)S(0.287)PPPSPR 151.3 0.00035227 16742200.0 103812.0 89652.0 130786.0 184166.0 146952.0 120048.0 120939.0 151573.0 107834.0 118261.0 True False 136822.0565762596 118630.25575958665 129051.69218594578 141709.37403633632 126550.2513761608 112541.37958245446 131702.33671011316 128150.87565103703 113533.88509252584 114120.71838584666 1.1989238984078143 1.0395155011072843 1.1308349089568197 1.241749754476758 1.1089156567371876 0.9861608056299437 1.154061581218078 1.1229413682601774 0.9948577847947232 1.0 16.800201208211426 -6.525816539098632 24.94977590591534 1.063674662667482 1.147130503586243 0.3059000977910983 0.07068440730799569 135.32081162102975 1149220.4109623283 0.023628331753736586 0.023759097797736342 2.979774922837916e-07 6.525816539098632 0.0834558409187609 TWTTPEVT(ph)SPPPSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TWTTPEVTSPPPSPR 15 0 Q5T1S5;Q7Z6M1-2;Q7Z6M1 Q5T1S5 RABEPK Rab9 effector protein with kelch motifs 1 TWTT(0.004)PEVT(0.613)S(0.38)PPPS(0.003)PR;TWTT(0.002)PEVT(0.715)S(0.283)PPPSPR;TWTT(0.007)PEVT(0.641)S(0.336)PPPS(0.014)PR 145.61 1.0629000000000001e-09 0.0 32000.6 36706.0 42423.0 43032.3 42759.0 52724.0 45966.0 58479.0 43004.0 33097.9 True False 37417.66953934002 40349.92909849704 43434.5252101234 40621.339743598954 34380.6808980498 49959.06062470259 41611.76771497885 56943.9882136222 43632.852144425 39098.28726716777 0.9570155665299687 1.032012702315488 1.1109060842825442 1.038954455115228 0.8793398202616536 1.277781307485942 1.064286203399036 1.4564317824080264 1.1159786065888637 1.0 15.254817790015998 -6.772750081221545 24.99962320246717 1.204009486302333 1.0131421619830174 0.3139367592119311 0.13026308168628772 249.50272583750618 551463.1546980494 0.04397294355224975 0.03912482006010428 1.6875238472415244e-07 6.772750081221545 -0.19086732431931552 TWTTPEVTS(ph)PPPSPR ddPTM_PC-9_Lapatinib_30min_R1 1 TWTTPEVTSPPPSPR 15 0 Q5T1S5;Q7Z6M1-2;Q7Z6M1 Q5T1S5 RABEPK Rab9 effector protein with kelch motifs 1 TWT(0.001)T(0.001)PEVT(0.152)S(0.818)PPPS(0.029)PR 88.155 0.0049373 3492500.0 20830.0 16811.0 21559.0 16227.0 19970.0 17932.0 15853.0 15877.0 18204.0 15796.0 True False 20532.960380245848 16772.07516236477 19786.502240146612 17420.387711685147 18795.403862530617 17165.090161533673 16673.790770675263 16614.703381838117 16153.673823381703 18526.317553153018 1.10831309683296 0.9053107890569602 1.068021326061051 0.9403049290127464 1.0145245437257338 0.9265246648334776 0.9000056661469418 0.8968162903485609 0.8719311745054531 1.0 14.17728852719834 -6.844493706678148 4.608450306048104 0.909281766838809 1.0013234231297377 0.32793280761920673 0.06242554423716456 0.24021847958492054 9.217974552878822 0.02079690647748125 0.01847369314744267 1.4305607107950638e-07 6.844493706678148 0.09204165629092864 TY(ph)KDPATLR ddPTM_PC-9_Lapatinib_30min_R1 2 TYKDPATLR 9 1 Q96JB3-2;Q96JB3 Q96JB3-2 HIC2 Hypermethylated in cancer 2 protein 1 T(0.001)Y(0.999)KDPATLR;T(0.003)Y(0.997)KDPATLR 93.649 0.02843 15097200.0 58970.1 73988.0 88074.0 60433.0 78108.0 63589.0 70170.0 80786.0 83519.0 71016.0 True False 58129.17556020808 73816.68533180919 80832.89569547171 64877.44441857815 73513.84100623637 60869.44670319899 73803.05925555319 84539.61248379278 74112.2107259403 83291.0209771282 0.697904466511107 0.8862502159996254 0.9704875117051154 0.7789248307616924 0.8826142379311612 0.7308044251242136 0.8860866200189765 1.0149907095869006 0.8897983222740371 1.0 16.345873356653073 -7.5420471707541425 8.491901739998278 0.9619787913747845 0.8323381706415962 0.3860635207104879 0.0807608456977488 0.22960061211996996 83.25411172305577 0.037391703040844736 0.02187636423633277 2.870468790056775e-08 7.5420471707541425 -0.12964062073318827 TYAENLS(ph)PHEGR ddPTM_PC-9_Lapatinib_30min_R1 1 TYAENLSPHEGR 12 0 E9PQ01 E9PQ01 PCF11 1 TYAENLS(1)PHEGR 70.197 0.037110000000000004 0.0 10571.0 11223.0 16675.0 12762.0 12144.0 13954.0 14441.0 15535.0 16413.0 11829.0 True False 10420.255601516023 11197.013833039067 15304.04586736143 13700.560052783987 11429.713796022623 13357.21994836274 15188.684319644319 16256.812813305754 14564.395103447812 13873.62688884826 0.751083742196636 0.8070718581915536 1.1031034631371668 0.9875254800023933 0.823844686583717 0.962777798147317 1.0947882944619993 1.1717781473835887 1.0497900239161542 1.0 13.760057370566965 -7.151349534410923 3.7741416872613343 1.0936141650603048 0.9055806772569278 0.4170278363000741 0.1016356709537985 0.2559068225315491 6.5374608211588825 0.04392044069623951 0.03318470275557032 7.057493154809555e-08 7.151349534410923 -0.18803348780337703 TYAGGTAS(ph)ATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TYAGGTASATK 11 0 H0Y944;D6RBR1;D6RGF7;E7EN75;P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;F8W7E0;E9PSG1;H0YA91 H0Y944;P20810-6 CAST Calpastatin 1 TYAGGT(0.081)AS(0.915)AT(0.005)K;T(0.005)YAGGT(0.005)AS(0.815)AT(0.175)K 113.99 0.0015024 7910800.0 41757.0 32322.0 33291.0 40703.0 41363.0 34157.0 36049.0 32447.0 27776.0 25638.0 True False 48825.63536165642 35530.71455134368 34084.78369682057 38422.54287090644 33258.217076779954 32365.746790038047 32634.177747841295 31595.300630438265 28182.171452970622 30285.96644970368 1.6121537822721235 1.1731742029877112 1.1254316005872105 1.268658305314948 1.098139533767639 1.068671420599646 1.0775346331455964 1.0432323724226868 0.9305356492345437 1.0 14.886361829241066 -1.5228787452803376 0.6512259694218059 1.0494196479662838 46.727583172816544 0.799238337477499 0.08069831577506924 103.43880672891609 0.6644947848081749 0.035370116775328475 6813.648972561722 0.029999999999999995 1.5228787452803376 45.67816352485026 TYAGGTAS(ph)ATK ddPTM_PC-9_Lapatinib_30min_R1 2 TYAGGTASATK 11 0 H0Y944;D6RBR1;D6RGF7;E7EN75;P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;F8W7E0;E9PSG1;H0YA91 H0Y944;P20810-6 CAST Calpastatin 1 T(0.389)YAGGT(0.152)AS(0.455)AT(0.003)K;T(0.202)YAGGT(0.02)AS(0.655)AT(0.123)K 109.0 0.0021156 17340700.0 49062.0 50923.0 45958.0 40058.0 34789.0 33795.0 35918.0 27989.0 40319.0 25259.8 True False 48362.36688313109 50805.090922199786 42179.51064301029 43003.99894957068 32742.77941780557 32349.666629992746 37777.65829187626 29289.471118868012 35777.84964210762 29625.922773432183 1.6324341102549995 1.7148863618776653 1.4237366027577667 1.4515665648104517 1.1052070738255118 1.0919378571729468 1.275155497460297 0.9886433358671315 1.2076535106002617 1.0 14.8545724706041 -5.868340306159541 1.1623894263337298 1.1063814362477702 1.6853748830533615 0.8325907903496651 0.09997710793483061 0.18968995433553018 0.5125392798912084 0.0355838224520182 0.08300535598166246 1.3541279236966186e-06 5.868340306159541 0.5789934468055913 TYAGGTASAT(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 TYAGGTASATK 11 0 H0Y944;D6RBR1;D6RGF7;E7EN75;P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;F8W7E0;E9PSG1;H0YA91 H0Y944;P20810-6 CAST Calpastatin 1 TYAGGT(0.002)AS(0.196)AT(0.802)K 105.03 0.0063788000000000004 6992300.0 16620.0 15751.0 20272.0 29794.0 21744.0 24102.0 14965.0 28337.0 21665.0 24999.0 True False 21904.814282524527 20842.20272240717 20003.180034510504 22925.453612711357 18725.220928760664 22594.898129884084 16296.856008953595 23958.16776948025 22810.16767002589 24123.792619103413 0.9080170198933937 0.8639687403838159 0.82918885725581 0.9503254307764567 0.7762138078542563 0.9366229633391637 0.6755511567467324 0.9931343776561896 0.9455464996810959 1.0 14.558169117742755 TYDATTHFETTCDDIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TYDATTHFETTCDDIK 16 0 P50395;P50395-2 P50395 GDI2 Rab GDP dissociation inhibitor beta 0 107.61 0.00074537 5393300.0 46808.0 55273.0 40493.0 56863.0 66877.0 48563.0 56516.0 49149.0 43477.0 42382.0 False True 54731.66989985898 60760.13815346884 41458.50669055765 53677.15046233338 53772.931930561484 46016.27078972444 51162.39533959329 47858.89082767004 44112.76887459695 50065.52110427263 1.0932008434680636 1.2136124185529256 0.8280849929477625 1.072138055859615 1.0740511782263755 0.9191209793639274 1.0219087749638354 0.9559251511233292 0.8811007635918191 1.0 15.611529776259731 -5.242983948033322 24.985658066036073 0.9750047728618623 1.1534066425644625 0.4611742869758292 0.07950454337333311 725.5580662846111 982284.3974966726 0.019877423779991896 0.05237270616119518 5.714997594950799e-06 5.242983948033322 0.1784018697026002 TYEDLKR ddPTM_PC-9_AZD4547_30min_R2 1 TYEDLKR 7 1 Q12874 Q12874 SF3A3 Splicing factor 3A subunit 3 0 63.148 0.040559 4830900.0 19781.0 19074.0 23516.0 34305.0 30138.0 28974.0 22773.0 27220.0 22429.0 28408.0 False True 26070.94652964005 25239.29748760044 23204.162474918554 26396.512256966613 25953.85891974746 27162.251199703824 24799.752882853343 23013.77445337378 23614.55115028899 27413.444566722224 0.9510277508609092 0.9206904818608228 0.8464519086042398 0.9629038843593524 0.9467565761966817 0.990836855018091 0.9046565754439448 0.83950684845022 0.8614222518740022 1.0 14.742595997282736 -10.714842490860187 4.791150080449618 1.0000039008715482 0.9142518391998334 0.21964448226698918 0.04873340388695742 6.5249030330647195e-06 1.1004216326236754e-06 0.051304402087384626 0.012441472599262515 1.9282241112360658e-11 10.714842490860187 -0.08575206167171479 TYFPHFDLHPGS(ph)AQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TYFPHFDLHPGSAQLR 16 0 P02008 P02008 HBZ Hemoglobin subunit zeta 1 TYFPHFDLHPGS(1)AQLR 74.96600000000001 0.012721 1542100.0 2268.9 993.85 1675.1 2072.5 2924.2 2507.5 3183.9 1208.0 979.62 818.34 True False 2652.979957182322 1092.5128598741692 1715.0407368521253 1956.3845441356561 2351.2240015453417 2376.0022857985314 2882.29794256018 1176.2912799817987 993.9450892410388 966.6985640241246 2.744371467915116 1.1301484253026208 1.7741215314449617 2.023779300955735 2.432220434628333 2.457852296695081 2.9815891424953547 1.216812896757798 1.0281851305369625 1.0 9.916922288388246 -7.910749995313046 8.556460574620779 1.0502645781918887 2.170126458623366 0.5318178261157478 0.4902438547936434 0.2232143016734882 18.8153011702417 0.2872865825302146 0.13754220011187085 1.228146018638207e-08 7.910749995313046 1.1198618804314775 TYGGCEGPDAMYVK ddPTM_PC-9_Lapatinib_30min_R1 2 TYGGCEGPDAMYVK 14 0 R4GMY8;E5RHG8;Q15369 R4GMY8 TCEB1 Transcription elongation factor B polypeptide 1 0 ; 125.23 0.00050216 2835600.0 15948.4 15278.3 14789.7 15850.5 16352.400000000001 15463.300000000001 16484.5 14716.5 14836.599999999999 15736.2 False True 15720.972891421627 15242.92403504596 13573.747955892975 17016.198645717966 15390.583982055372 14801.970705712887 17337.986750722037 15400.282315224587 13165.545871675728 18456.181202831518 0.8517998777022052 0.8258980483301397 0.7354580997400758 0.9219783041091604 0.8338986171036386 0.8020061432557886 0.9394135525751162 0.8344240959696418 0.7133407353876592 1.0 14.171816453135904 -10.697248734117105 4.595062034498666 1.0000271035513726 0.8314038024578576 0.37271693084898605 0.06658843293195131 1.834245733361198e-05 3.295720711265275e-06 0.06396223492675539 0.015510628553995723 2.0079424713782216e-11 10.697248734117105 -0.16862330109351498 TYGGDT(ph)GSPEISFTK ddPTM_PC-9_AZD4547_30min_R2 1 TYGGDTGSPEISFTK 15 0 H0Y9X0;A0A286YEZ9;A0A2C9F2R7;O94915 H0Y9X0 FRYL Protein furry homolog-like 1 T(0.032)Y(0.018)GGDT(0.848)GS(0.102)PEIS(0.001)FTK 78.191 0.029707 7843900.0 12751.0 11761.0 15122.0 17473.0 16759.0 13853.0 11503.0 16492.0 11394.0 19560.0 True False 16805.552762723855 15562.513251109829 14921.472399460727 13444.869805158944 14432.302131397171 12986.76972007652 12526.744715736264 13943.540348458502 11996.263578687978 18875.21035360065 0.8903504887042498 0.8244948246704499 0.7905327739361747 0.7123030447496014 0.7646167571660495 0.6880331120441873 0.6636611979980743 0.7387223817507613 0.635556550308832 1.0 14.204205102101362 -5.13238185114514 1.2285861697397427 0.7262768827384002 0.9110584661334359 0.17869627117831755 0.09556896128451584 1.209996619038478 2.3742987212594837 0.02790455616324505 0.24315255434896096 7.372557168481351e-06 5.13238185114514 0.1847815833950357 TYGGDT(ph)GSPEISFTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TYGGDTGSPEISFTK 15 0 H0Y9X0;A0A286YEZ9;A0A2C9F2R7;O94915 H0Y9X0 FRYL Protein furry homolog-like 1 TYGGDT(0.753)GS(0.245)PEIS(0.002)FTK 172.91 0.00021227 5377500.0 39411.0 35278.0 36916.0 31471.0 44863.0 36615.0 40264.0 39485.0 34447.0 25934.0 True False 46082.50389726849 38780.16669582023 37796.21744470962 29707.781900358634 36072.41720174019 34694.844942976364 36449.902433883944 38448.56058781566 34950.722207678555 30635.628906568953 1.5042127595228636 1.2658518228592628 1.2337340147309748 0.9697134663355526 1.177466188526832 1.132499843524904 1.1897879604511166 1.2550276250268666 1.1408521207209281 1.0 14.902922847677981 -4.746908971259778 1.59977278223994 1.1415107327859964 1.6558851736362434 0.6396848503076058 0.0851091664980618 0.7457587037994355 1.728095671632067 0.024055448915501026 0.6199564057454908 1.7909812069013157e-05 4.746908971259778 0.5143744408502471 TYGGDT(ph)GSPEISFTK ddPTM_PC-9_Lapatinib_30min_R1 2 TYGGDTGSPEISFTK 15 0 H0Y9X0;A0A286YEZ9;A0A2C9F2R7;O94915 H0Y9X0 FRYL Protein furry homolog-like 1 T(0.04)YGGDT(0.92)GS(0.039)PEISFTK;T(0.007)Y(0.005)GGDT(0.821)GS(0.165)PEIS(0.002)FTK 171.46 0.00030431 20970900.0 95610.0 86147.0 93026.0 84960.0 99282.0 92355.0 80547.0 73565.0 103896.0 66133.0 True False 94246.58386727341 85947.53191435598 85377.7613707446 91208.24181825179 93442.42795592207 88405.19194002011 84717.32954050225 76983.0984622359 92194.13840661754 77564.00093331661 1.2150815163377038 1.1080853344355825 1.100739522760638 1.175909451817286 1.2047138728217035 1.139770910167771 1.0922248532967698 0.9925106690721108 1.1886202013467402 1.0 16.24309960251172 -7.304347514536878 3.5054052386778927 1.0646007843125467 1.1563667204119323 0.34878329285953713 0.06057682349839921 0.2913368373208185 7.417930610298392 0.02618393213345514 0.017526403748683424 4.961951162559344e-08 7.304347514536878 0.09176593609938566 TYS(ph)APAINAIQGGSFESPK ddPTM_PC-9_AZD4547_30min_R2 2 TYSAPAINAIQGGSFESPK 19 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3 Q9H4L5-5 OSBPL3 Oxysterol-binding protein-related protein 3 1 T(0.006)YS(0.994)APAINAIQGGSFESPK;T(0.127)Y(0.035)S(0.782)APAINAIQGGS(0.052)FES(0.004)PK 234.22 1.7815000000000001e-43 20813200.0 115646.0 104206.0 106210.0 98239.0 85226.0 103034.0 77870.0 89871.0 96359.0 74280.0 True False 152419.02241376837 137888.55164060465 104801.58600361878 75591.51632742003 73393.84100784385 96591.26769207856 84800.27914582135 75983.50198013053 101452.34001920257 71679.47980907229 2.1263968826190767 1.9236823705736832 1.4620863081424638 1.0545767983915058 1.0239170429715447 1.3475442058084417 1.1830481941512137 1.0600453879202607 1.4153609971700996 1.0 16.129272547084547 -5.320168869095183 2.2276975921092257 1.1617285304667306 2.1010336410213117 0.8700199166408327 0.13372908938918895 0.10511449605530532 0.9788764600124887 0.03705775510996635 0.12099113393376883 4.784440201480029e-06 5.320168869095183 0.9393051105545811 TYS(ph)APAINAIQGGSFESPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 TYSAPAINAIQGGSFESPK 19 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3 Q9H4L5-5 OSBPL3 Oxysterol-binding protein-related protein 3 1 T(0.138)YS(0.861)APAINAIQGGSFESPK;T(0.033)YS(0.967)APAINAIQGGSFESPK;T(0.033)YS(0.967)APAINAIQGGSFESPK;T(0.211)YS(0.789)APAINAIQGGSFESPK;T(0.016)YS(0.984)APAINAIQGGSFESPK 240.82 1.6821999999999998e-72 25232700.0 162276.0 213283.0 151708.0 139705.0 143594.0 98511.0 128731.0 95169.0 104315.0 91521.0 True False 189746.12170290362 234456.3267017584 155325.2940757939 131877.7817797213 115457.78649815412 93344.90974129582 116536.66774826901 92670.91458989058 105840.40953040846 108113.0328201628 1.7550716759424443 2.1686222334707543 1.436693523658381 1.2198139145637437 1.0679358767985792 0.8634010840910129 1.0779150737739291 0.8571669129293698 0.9789791921429615 1.0 16.722180922131727 -5.627220255642317 1.6662156824628356 0.9698242980260732 1.9814524506482754 0.8883845272010084 0.1351581369015573 0.1061871009483552 0.5842930205974284 0.03942573599512743 0.10056317430428546 2.3592814027910137e-06 5.627220255642317 1.0116281526222022 TYS(ph)APAINAIQGGSFESPK ddPTM_PC-9_Lapatinib_30min_R1 3 TYSAPAINAIQGGSFESPK 19 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3 Q9H4L5-5 OSBPL3 Oxysterol-binding protein-related protein 3 1 T(0.04)YS(0.96)APAINAIQGGSFESPK;T(0.002)YS(0.998)APAINAIQGGSFESPK;T(0.151)YS(0.849)APAINAIQGGSFESPK 264.03 2.7479e-78 15781600.0 107930.0 138807.0 122762.0 91329.0 110562.0 120370.0 114609.0 114882.0 116371.0 86855.0 True False 106390.89840806188 138485.60091977668 112668.98223502404 98045.63932461297 104058.96053325523 115222.05569617484 120542.89323385627 120219.8371173603 103264.07253904383 101867.77102298735 1.044401947148268 1.3594643284039876 1.1060316830688217 0.962479480408854 1.0215101350335174 1.1310943052849756 1.183327091810566 1.1801557637913922 1.0137069997903596 1.0 16.636338157541715 -14.522878745280336 0.10731760360641822 0.6593730909231452 1.180650318274569 0.09842334074207948 0.10713236752950828 478.9861487812875 3.426635976945787 36.74322680363213 1.5670311620075215 3.0000000000000132e-15 14.522878745280336 0.5212772273514237 TYS(ph)APAINAIQVPK ddPTM_PC-9_AZD4547_30min_R2 2 TYSAPAINAIQVPK 14 0 Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 T(0.022)YS(0.978)APAINAIQVPK;TYS(1)APAINAIQVPK 158.91 0.00022193 35962000.0 344450.0 337570.0 244890.0 174182.0 148184.0 189662.0 189742.0 195933.0 209063.0 167049.0 True False 453977.93499492086 446682.90095885954 241642.59859171667 134027.03098507388 127611.20944202863 177802.4051576663 206628.67042104094 165656.0569424276 220113.6433694262 161200.66535575857 2.8162286674997485 2.770974300714341 1.4990173772448667 0.8314297629559135 0.7916295454513146 1.1029880352247237 1.2818102826376427 1.0276387915449126 1.3654636156969377 1.0 17.298498173038872 -5.339288253861662 3.1195601830845905 1.0617525983369294 2.841628620990251 0.9415493988680389 0.1703849142901299 0.054994465869134 1.0297373162522503 0.04967638890630121 0.12737893282683088 4.578379055293839e-06 5.339288253861662 1.7798760226533215 up TYS(ph)APAINAIQVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TYSAPAINAIQVPK 14 0 Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 T(0.143)Y(0.013)S(0.843)APAINAIQVPK 64.65 0.040748 13440000.0 88091.0 125920.0 82578.0 67397.0 68082.0 43748.0 62097.0 46862.0 49719.0 42172.0 True False 103003.0664234423 138420.5054237114 84546.97269880901 63620.96459402214 54741.82083072626 41453.77786604749 56214.722616652354 45631.92215439328 50446.04631589311 49817.449766631704 2.067610182896896 2.7785546243763575 1.6971357043539297 1.277081923945376 1.098848316948431 0.8321136079874908 1.128414298202507 0.9159827002015278 1.0126179993597835 1.0 15.604363549197164 -5.610370526498107 2.1073950213908414 1.005639090868791 2.4312949199804037 0.8857914237476476 0.19927809158555274 0.08728189384689518 0.7766878212989355 0.05480245241708696 0.12418224887470498 2.4526155277805266e-06 5.610370526498107 1.4256558291116126 up TYS(ph)APAINAIQVPK ddPTM_PC-9_Lapatinib_30min_R1 2 TYSAPAINAIQVPK 14 0 Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 T(0.214)YS(0.786)APAINAIQVPK;T(0.182)YS(0.818)APAINAIQVPK 133.23 1.0793e-05 23507000.0 122072.0 221690.0 173308.0 157926.0 180105.0 195492.0 192756.0 197668.0 171488.0 151877.0 True False 120331.23089473696 221176.69042559311 159059.2852282265 169540.40486569214 169511.57800005368 187131.26287410993 202735.96251764824 206852.37690251126 152173.21559130304 178128.73708661852 0.6755295796894556 1.2416676502794812 0.8929456741776644 0.9517858131068984 0.9516239814669848 1.0505394353248783 1.13814292872387 1.1612521386817294 0.8542878486659111 1.0 17.442560756221347 -6.7767381630732375 7.634702425635884 1.0572861034062773 0.9569706506918815 0.0875631065493836 0.15042922837349723 0.392548417613495 117.5719802360465 0.050097047064791574 0.04568732825584194 1.672098421631221e-07 6.7767381630732375 -0.10031545271439579 TYS(ph)APAINAIQVPKPFSGPVR ddPTM_PC-9_AZD4547_30min_R2 2 TYSAPAINAIQVPKPFSGPVR 21 1 Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 T(0.245)Y(0.118)S(0.637)APAINAIQVPKPFSGPVR;T(0.189)Y(0.055)S(0.755)APAINAIQVPKPFSGPVR 161.48 1.4432e-06 154347000.0 195033.0 127907.0 154919.0 169098.0 143080.0 101919.0 91106.0 131279.0 89352.0 118391.0 True False 257049.43706158924 169250.43639228863 152864.67283772342 130115.06863805673 123215.81174057556 95545.98881834089 99214.2575042916 110992.8470413097 94074.96430427674 114246.16712541574 2.249961145562185 1.4814539572823566 1.3380288957082782 1.138900953195398 1.0785115583379987 0.8363167992625398 0.8684252610013375 0.9715235953558542 0.8234408792113288 1.0 16.801786239178256 -1.522878745280394 0.5425711178657394 0.8926853646473982 57.826086229736184 0.9578855207031443 0.08438506537572434 22.96608582773611 0.21532271033365213 0.04216816863298794 1519.2817109834173 0.0299999999999961 1.522878745280394 56.933400865088785 up TYS(ph)APAINAIQVPKPFSGPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TYSAPAINAIQVPKPFSGPVR 21 1 Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 T(0.153)Y(0.001)S(0.845)APAINAIQVPKPFSGPVR;T(0.181)Y(0.148)S(0.671)APAINAIQVPKPFSGPVR 144.83 7.9465e-05 110290000.0 57845.0 39730.0 47890.0 47838.0 49370.0 44325.0 43732.0 42150.0 41905.0 31816.0 True False 67637.01600917245 43674.131833577274 49031.8792238364 45157.79195288859 39696.30290551036 42000.51897029705 39589.388367738225 41043.60716161655 42517.781348528726 37583.98894468256 1.799623134966408 1.162040886555666 1.3045948713959885 1.2015167421253081 1.0562024952683116 1.1175109441447233 1.0533578121792042 1.092050320204861 1.1312737828629071 1.0 15.197830573644008 -2.0710527053723866 1.0087374271679561 1.1015732936765745 199.99999999999906 0.8568916641961671 0.0825886695068503 172.61435312699314 0.7968683564708428 0.025705607567616674 78635.06566820531 0.00849077425931733 2.0710527053723866 198.89842670632248 TYS(ph)APAINAIQVPKPFSGPVR ddPTM_PC-9_Lapatinib_30min_R1 1 TYSAPAINAIQVPKPFSGPVR 21 1 Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-6 OSBPL3 Oxysterol-binding protein-related protein 3 1 T(0.157)YS(0.842)APAINAIQVPKPFSGPVR 134.69 2.5481999999999998e-05 53206000.0 58415.0 33899.0 39422.0 25504.0 27894.0 35276.0 21504.0 25680.0 35159.0 20855.0 True False 57581.991388001006 33820.50894824834 36180.875333320655 27379.64923884994 26253.329761714005 33767.32771237239 22617.3719001199 26873.186549449096 31199.023179316497 24459.758962459262 2.3541520370817066 1.3827000094381927 1.4791999949325303 1.1193752677968787 1.0733274110348965 1.3805257755891358 0.9246768103820217 1.0986693119377813 1.2755245555445018 1.0 14.578122566514581 -2.0708919594411452 0.9051643469518312 1.1315916345835746 199.99999999838514 0.8485592448941305 0.15131543222488683 104.18369720446131 0.6920675674923095 0.04848754777225459 42197.30130098364 0.008493917541333265 2.0708919594411452 198.86840836380156 up TYS(ph)DEANQMR ddPTM_PC-9_AZD4547_30min_R2 3 TYSDEANQMR 10 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 T(0.079)YS(0.921)DEANQMR;T(0.048)YS(0.952)DEANQMR;T(0.015)YS(0.984)DEANQMR 114.71 0.001185 36205500.0 96509.0 90346.0 124795.0 199145.0 155248.0 130091.0 107973.0 138755.0 98420.0 114102.0 True False 127196.85448809653 119548.5776876769 123140.13676039549 153235.19700957922 133694.49497554466 121956.38920482743 117582.38782858322 117313.60302269929 103622.28027158773 110107.32370994569 1.1552079389666174 1.0857459218843806 1.1183646338074837 1.3916894158034823 1.214219821814345 1.1076137816780978 1.0678888911906441 1.0654477746797026 0.9411025241568725 1.0 16.748550906360173 -7.418383457445084 1.4026752277535963 0.9910241212317508 1.1899765206156552 0.5109322377078152 0.08187864938706048 0.4083697797846583 1.5442565453724268 0.0604867927051227 0.0310042709484428 3.8160718450412075e-08 7.418383457445084 0.1989523993839044 TYS(ph)DEANQMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TYSDEANQMR 10 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 T(0.005)YS(0.995)DEANQMR 87.641 0.025144999999999997 0.0 20374.0 20761.0 29037.0 27486.0 24690.0 25812.0 23693.0 23392.0 24280.0 14871.0 True False 23822.915795157398 22822.01487533093 29729.352203435716 25946.04853081431 19852.171738647987 24458.37328057097 21448.627517534573 22777.984785872708 24635.049066752854 17566.994581228777 1.356117899678377 1.2991416812820906 1.6923414000026524 1.4769770896689964 1.1300835579388768 1.3922912748379839 1.220961697139334 1.2966352713634999 1.4023485322342304 1.0 14.100579771030281 -6.237684768690853 24.39057021498826 1.2618424593012212 1.461801273279782 0.3344580372532917 0.1471627321506795 747.3494560166483 767356.856254962 0.043148451209146364 0.05567119098680285 5.785158089601958e-07 6.237684768690853 0.19995881397856086 TYS(ph)DEANQMR ddPTM_PC-9_Lapatinib_30min_R1 1 TYSDEANQMR 10 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 T(0.163)YS(0.837)DEANQMR 134.98 0.00011253 7695500.0 18159.0 14284.0 17458.0 16241.0 20281.0 14210.0 9235.6 15646.0 21698.0 9487.8 True False 17900.049330047248 14250.926275606353 16022.670629828834 17435.417318387765 19088.111453980127 13602.271425127883 9713.774177862137 16372.970278531177 19254.14274993059 11127.75358830117 1.60859504912707 1.2806651551476336 1.439883665888665 1.566840708686969 1.7153607242029372 1.22237352913963 0.8729321781598779 1.471363483079317 1.7302811926185044 1.0 13.441874758022475 -6.790771976232809 24.940534040990933 1.2646965635480454 1.5067459842515656 0.2228168687635551 0.24452056756958832 375.6738179771094 319420.3583187101 0.09090308391311273 0.08018103263575974 1.6189298241323235e-07 6.790771976232809 0.2420494207035202 TYS(ph)FEQPWPNAR ddPTM_PC-9_AZD4547_30min_R2 1 TYSFEQPWPNAR 12 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-5 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 T(0.081)YS(0.919)FEQPWPNAR 74.53699999999999 0.020727000000000002 45590000.0 17049.0 17717.0 28750.0 31047.0 29671.0 25513.0 21102.0 23776.0 20796.0 22424.0 True False 22470.22735877019 23443.673775181764 28368.75621508372 23889.593821368395 25551.693808740714 23917.668076828995 22980.037120009263 20101.965518126908 21895.23410412456 21638.942585334407 1.0384161458055339 1.083402004637255 1.3110047361699817 1.1040092983822298 1.180819890250004 1.1053066933612077 1.0619759736126742 0.9289717110183946 1.0118439945842757 1.0 14.40134238129426 -7.397164492833081 2.2926759569491084 0.9785110089145405 1.1457766428110066 0.4860456330680305 0.07190494856155848 0.26449611135809753 2.7158944518060317 0.03834544096723622 0.022569061939542973 4.007149146024554e-08 7.397164492833081 0.1672656338964661 TYS(ph)FEQPWPNAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TYSFEQPWPNAR 12 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-5 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 TYS(1)FEQPWPNAR 128.57 0.00020102 23658000.0 14296.0 17912.0 24090.0 19829.0 28644.0 22952.0 26879.0 24785.0 21061.0 25954.0 True False 16716.03044112939 19690.184983715986 24664.396961833765 18718.04541648537 23031.41382267449 21748.356715313203 24332.826532892057 24134.420011878217 21368.977281502535 30659.254748249026 0.5452197249538187 0.6422264711062655 0.8044682483106464 0.6105186042578015 0.7512059249903924 0.7093569916781903 0.7936535552705084 0.7871822133333672 0.6969829324609703 1.0 14.904035008572473 -14.522878745191656 0.07993057965353674 1.925231481476028 0.42848249810140215 0.6677118843448226 0.06909887896189901 156.66976664335832 0.8834622906303428 25.751864620228332 2.3947171328750416 3.000000000612588e-15 14.522878745191656 -1.496748983374626 TYS(ph)FEQPWPNAR ddPTM_PC-9_Lapatinib_30min_R1 1 TYSFEQPWPNAR 12 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-5 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 T(0.01)YS(0.99)FEQPWPNAR 85.271 0.009756200000000001 32950000.0 17106.0 16565.0 17532.0 19258.0 26735.0 25911.0 23530.0 24458.0 28431.0 24895.0 True False 16862.065303143787 16526.644760250558 16090.586635477084 20674.297562804735 25162.499863032353 24802.846931491127 24748.268266825777 25594.40796831876 25228.80138829737 29198.06757949763 0.5775062084925111 0.5660184433525758 0.5510839575827138 0.7080707483984955 0.8617864793456749 0.8494687829583369 0.8475995269016904 0.8765788317542871 0.8640572298014882 1.0 14.833585269691405 -6.053233722403227 2.1974590390348827 0.8770454210479829 0.5619174033543558 0.9188588261145836 0.04266035894374747 0.07758600992669647 0.7444637261574073 0.012995266413144623 0.01942409846863998 8.846393991016382e-07 6.053233722403227 -0.3151280176936271 TYS(ph)LTTPAR ddPTM_PC-9_AZD4547_30min_R2 5 TYSLTTPAR 9 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 T(0.009)YS(0.977)LT(0.013)TPAR;T(0.001)YS(0.994)LT(0.004)TPAR;T(0.001)YS(0.986)LT(0.012)T(0.001)PAR;T(0.002)YS(0.981)LT(0.017)T(0.001)PAR;T(0.007)YS(0.495)LT(0.495)T(0.003)PAR 128.81 0.0013181 390780200.0 148391.0 158025.0 222195.0 271332.0 243285.0 225275.0 191121.0 237280.0 172616.0 192163.0 True False 195576.2512754569 209103.49090269807 219248.549120366 208780.59943761138 209509.07715477992 211188.5186378574 208130.39874956376 200613.82815196694 181740.12935745166 185435.4318598651 1.0546865251903708 1.1276350415098615 1.1823444253418285 1.1258937806200295 1.129822251623991 1.1388789969624258 1.1223874351415721 1.081852729760795 0.9800722954326981 1.0 17.50055740601951 -8.090316956953272 2.6661641229445356 0.9884476717789169 1.1287841384676243 0.7619702470103307 0.029902018522226202 0.1366584044838797 1.7670539971433896 0.025519449128547003 0.008287713784308004 8.122375123271056e-09 8.090316956953272 0.14033646668870736 TYS(ph)LTTPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 TYSLTTPAR 9 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 TYS(0.988)LT(0.011)TPAR;T(0.005)YS(0.983)LT(0.011)TPAR;T(0.002)YS(0.978)LT(0.019)T(0.001)PAR;T(0.014)YS(0.977)LT(0.007)T(0.002)PAR;T(0.008)YS(0.908)LT(0.083)TPAR;T(0.028)YS(0.675)LT(0.297)T(0.001)PAR 117.52 0.0018532 296885900.0 210802.0 210560.0 226752.0 282343.0 313061.0 277094.0 295400.0 279170.0 264111.0 218698.0 True False 246486.61507071657 231463.005257438 232158.6276417487 266524.2370783569 251718.94437719233 262562.7028438914 267417.5734892045 271842.08330506465 267973.1237260774 258346.21618758468 0.9540941559281175 0.8959411470124771 0.8986337445452608 1.0316552764404887 0.9743473238811429 1.0163210699135812 1.0351131804269706 1.0522394611256107 1.0372635902339 1.0 17.978946228231003 -5.7632276171352785 24.999995317544915 1.0216183732180222 0.914194814685637 0.7835715537991499 0.02522409020925808 21.04874804255118 294274.40246483963 0.007459759852578166 0.011745265680523764 1.7249336038434136e-06 5.7632276171352785 -0.10742355853238517 TYS(ph)LTTPAR ddPTM_PC-9_Lapatinib_30min_R1 4 TYSLTTPAR 9 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 T(0.272)YS(0.66)LT(0.057)T(0.011)PAR;T(0.001)YS(0.669)LT(0.29)T(0.04)PAR;T(0.1)YS(0.833)LT(0.021)T(0.045)PAR;T(0.059)YS(0.899)LT(0.016)T(0.026)PAR 89.171 0.009551700000000002 308699000.0 136090.0 111743.0 185495.0 140580.0 170489.0 176841.0 150165.0 151406.0 212291.0 140771.0 True False 134149.33164415078 111484.26594896936 170244.3171314064 150918.7221611328 160461.1722142706 169277.9226665054 157939.80893701204 158440.87549477722 188380.55205666504 165103.07978443292 0.8125186508895113 0.6752403776751407 1.0311395605320393 0.9140878677622493 0.9718847911485174 1.0252862810767875 0.9566133420601626 0.9596482131141696 1.1409875109696583 1.0 17.3330075065492 -5.265814031500766 24.998859330405576 0.9938022617121756 0.7438795066368786 0.709214567998973 0.06549364757496835 172.1348251234816 983666.2954512684 0.01652122844977842 0.03639841964878969 5.422330293766747e-06 5.265814031500766 -0.24992275507529693 TYS(ph)QDCSFK ddPTM_PC-9_AZD4547_30min_R2 2 TYSQDCSFK 9 0 Q86U86-8;Q86U86;E7EVG2;Q86U86-5;Q86U86-4;Q86U86-7;Q86U86-9;Q86U86-2;Q86U86-3;H0Y5B5 Q86U86-8 PBRM1 Protein polybromo-1 1 T(0.022)YS(0.978)QDCSFK;T(0.344)YS(0.656)QDCSFK 134.98 0.0010845999999999998 12884800.0 31620.0 38097.0 40591.0 55381.0 51328.0 53669.0 41873.0 43925.0 35707.0 37602.0 True False 41674.50226314235 50411.11022256024 40052.73681831176 42613.76607792063 44201.993185772044 50313.068945844694 45599.61588125051 37137.400546085344 37594.399122714705 36285.56542515803 1.1485146166207454 1.389288264683027 1.1038201099807534 1.1743999460560988 1.218170164026858 1.386586328649599 1.2566874829414876 1.0234758673578974 1.036070367988512 1.0 15.147108130771185 -7.763875037569072 24.897280079423954 1.0223297613442364 1.2424871494513647 0.5699363938112068 0.08745976207020438 45.78174411972908 467957.65854139946 0.04618812045850701 0.02383318114605727 1.722364090933803e-08 7.763875037569072 0.22015738810712837 TYS(ph)QDCSFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TYSQDCSFK 9 0 Q86U86-8;Q86U86;E7EVG2;Q86U86-5;Q86U86-4;Q86U86-7;Q86U86-9;Q86U86-2;Q86U86-3;H0Y5B5 Q86U86-8 PBRM1 Protein polybromo-1 1 T(0.197)Y(0.002)S(0.786)QDCS(0.016)FK 83.137 0.014756 4732400.0 11837.0 11613.0 10487.0 15054.0 17338.0 9492.6 19794.0 10572.0 12005.0 11915.0 True False 13840.770308593213 12765.861892356726 10737.049852168973 14210.573185726502 13940.743361874393 8994.791345232754 17918.969023850055 10294.49620195992 12180.550413771327 14075.095180911903 0.9833518090423664 0.9069822781496563 0.762840301551221 1.0096253704201112 0.9904546422378931 0.6390572304925611 1.2730975381360876 0.731397981302529 0.8653973743843747 1.0 13.780857057916432 TYS(ph)QDCSFK ddPTM_PC-9_Lapatinib_30min_R1 1 TYSQDCSFK 9 0 Q86U86-8;Q86U86;E7EVG2;Q86U86-5;Q86U86-4;Q86U86-7;Q86U86-9;Q86U86-2;Q86U86-3;H0Y5B5 Q86U86-8 PBRM1 Protein polybromo-1 1 T(0.009)Y(0.001)S(0.99)QDCSFK 73.95100000000001 0.028210000000000002 5375900.0 11426.0 12166.0 13540.0 13583.0 14989.0 22437.0 20667.0 26218.0 16286.0 19322.0 True False 11263.063144728223 12137.83037447681 12426.793465911458 14581.939131559699 14107.376489507828 21477.421813201585 21737.036135592352 27436.183993514638 14451.699180817095 22661.781955053353 0.497006950603753 0.5356079410944202 0.5483590606669131 0.6434595108399263 0.6225184108420045 0.9477375546106308 0.9591935964570169 1.210680786176951 0.6377123921446305 1.0 14.467973688044191 -6.718381376492937 2.954642250334559 0.9715166893760548 0.5585849843636068 0.6674150230803644 0.13492632300557905 0.1501068760507338 2.6792340896737867 0.047333064581505074 0.045121064406206376 1.91257565555614e-07 6.718381376492937 -0.412931705012448 TYS(ph)SPGSFK ddPTM_PC-9_Lapatinib_30min_R1 1 TYSSPGSFK 9 0 Q8N3Z6 Q8N3Z6 ZCCHC7 Zinc finger CCHC domain-containing protein 7 1 TYS(0.647)S(0.35)PGS(0.003)FK 133.75 0.0011541 8916000.0 97459.0 79186.0 91925.0 90071.0 90028.0 87947.0 79321.0 68061.0 91631.0 70950.0 True False 96069.21678820846 79002.64968217333 84367.28134076177 96695.1218080477 84732.73004185806 84185.71182447037 83427.85325936627 71223.36252889612 81310.55186279326 83213.61296506754 1.154489191913078 0.9493957402779526 1.0138639380575691 1.162010858110915 1.0182556317729916 1.0116819691486165 1.0025745822908647 0.8559099886552836 0.9771304113057419 1.0 16.34453193857327 -7.211231661822511 1.8011521778803816 0.9397731315206446 1.055627324631949 0.3172191386146419 0.07036571602566409 0.4277706440855812 2.7162517698147597 0.03635880667434957 0.02354063802759203 6.148488119159219e-08 7.211231661822511 0.1158541931113044 TYS(ph)SSGSSGGSHPSSR ddPTM_PC-9_AZD4547_30min_R2 2 TYSSSGSSGGSHPSSR 16 0 H0Y6B5;B7Z836;E7EW77;E7EP65;A0A0C4DG21;F8WAL6;Q9NYB9-3;Q9NYB9-2;Q9NYB9-4;Q9NYB9 H0Y6B5 ABI2 Abl interactor 2 1 T(0.096)YS(0.801)S(0.101)S(0.003)GSSGGSHPSSR;TYS(0.403)S(0.403)S(0.191)GS(0.001)S(0.001)GGSHPSSR 165.89 3.1715e-05 1592250.0 0.0 0.0 3848.6000000000004 17841.9 6961.1 6052.4 0.0 8315.5 2319.0 3097.8 True False 0.0 0.0 3797.56504936943 13728.725609607129 5994.6714223324125 5673.942471218588 0.0 7030.530546180364 2441.57760566767 2989.346964896935 0.0 0.0 1.270366101346941 4.5925500689012395 2.0053448103302034 1.8980541696384219 0.0 2.351861670370792 0.8167595245177066 1.0 11.545614640856918 -5.353925441452333 4.498118044960343 1.87084995247922 0.001987064153491165 0.2740128513046688 1.1466141897272923 0.27592519304119534 9.520890472605206 0.3177800143818705 0.7047528356777173 4.426643613064528e-06 5.353925441452333 -1.8688628883257288 TYSAPAINAIQGGS(ph)FESPKKEK ddPTM_PC-9_Lapatinib_30min_R1 1 TYSAPAINAIQGGSFESPKKEK 22 2 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3 Q9H4L5-5 OSBPL3 Oxysterol-binding protein-related protein 3 1 TYSAPAINAIQGGS(0.569)FES(0.43)PKKEK 41.905 0.031301 8072400.0 58216.0 38007.0 33193.0 52940.0 36602.0 34023.0 36970.0 24776.0 41609.0 33314.0 True False 57385.829164493094 37918.997126643124 30463.999668685326 56833.38420266294 34449.14232230073 32567.915601486715 38884.125704400714 25927.18340923482 36922.55625780539 39072.28051188526 1.4687094895071993 0.9704833357527896 0.7796831735843672 1.4545704386355178 0.8816772881178964 0.833529939251434 0.9951844426529618 0.6635697499496637 0.9449808348548798 1.0 15.253857842574757 -6.467397197311625 24.999791618245403 0.8714302005208566 1.131672261054222 0.2904371738501239 0.21204549326612043 416.2532522554971 187562.01341793156 0.06504311518307337 0.07375164537460277 3.4088100585434947e-07 6.467397197311625 0.2602420605333654 TYSAPAINAIQGGSFES(ph)PKK ddPTM_PC-9_AZD4547_30min_R2 1 TYSAPAINAIQGGSFESPKK 20 1 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3 Q9H4L5-5 OSBPL3 Oxysterol-binding protein-related protein 3 1 TYSAPAINAIQGGS(0.13)FES(0.87)PKK 81.38 0.00057881 9477800.0 22790.0 15375.0 16318.0 14719.0 20824.0 19575.0 24027.0 20700.0 26274.0 22850.0 True False 30036.745938552005 20344.668075487927 16101.612658008198 11325.761956283093 17932.947048404723 18350.972155525727 26165.356453533434 17501.2906386788 27662.790000565907 22050.028454998694 1.3622089422629629 0.9226594930255446 0.7302309242307575 0.5136393351780717 0.8132845309022431 0.8322425611820742 1.1866359495605006 0.7937083017555606 1.254546680382846 1.0 14.428492897094559 -7.2294813680366605 22.52632465315488 1.0415317765878265 0.841027692552032 0.14365997095447958 0.22981982930701017 407.5967842403942 287303.2980120131 0.09143113737722301 0.07080941119375633 5.8954726909184816e-08 7.2294813680366605 -0.20050408403579445 TYSAPAINAIQGGSFES(ph)PKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 TYSAPAINAIQGGSFESPKK 20 1 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3 Q9H4L5-5 OSBPL3 Oxysterol-binding protein-related protein 3 1 TYSAPAINAIQGGS(0.006)FES(0.994)PKK;TYSAPAINAIQGGS(0.249)FES(0.751)PKK 117.21 7.6341e-06 15499800.0 41671.0 53693.0 43084.0 50238.0 48836.0 42697.0 59090.0 56208.0 43253.0 41388.0 True False 48725.07726023383 59023.28619532502 44111.28595697986 47423.327733793536 39266.9363721593 40457.894156227274 53492.56742544707 54732.59955729882 43885.49329836331 48891.316772772276 0.996599815191907 1.2072345375691593 0.9022314977113803 0.969974442582486 0.8031474495697605 0.8275067399853382 1.094111816911367 1.1194748509571657 0.8976132408608655 1.0 15.577290641020808 -5.274973767349628 24.962061140438763 0.9520141206366124 1.1019171866244388 0.2369986799381837 0.107770457573779 1036.7849262919974 1912187.5912107383 0.03022029877050352 0.0634819236789163 5.309165121646204e-06 5.274973767349628 0.14990306598782643 TYSAPAINAIQGGSFES(ph)PKK ddPTM_PC-9_Lapatinib_30min_R1 2 TYSAPAINAIQGGSFESPKK 20 1 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3 Q9H4L5-5 OSBPL3 Oxysterol-binding protein-related protein 3 1 TYSAPAINAIQGGS(0.001)FES(0.999)PKK;TYSAPAINAIQGGS(0.001)FES(0.999)PKK 128.51 6.8904999999999995e-06 15896900.0 66292.0 68303.0 44468.0 69044.0 60081.0 48868.0 44652.0 50514.0 46127.0 43733.0 True False 65346.6639235361 68144.84860002382 40812.01269144397 74121.72608403215 56547.15370379079 46778.029556871894 46963.86207608606 52861.06485042331 40931.691521156245 51292.19077944047 1.2740080493837886 1.3285618641841757 0.7956769260829216 1.4450879355643058 1.1024515202898426 0.9119912572660477 0.9156142750469269 1.0305869967170849 0.7980102019265467 1.0 15.646451572216513 -6.622320448930502 4.570115911949684 0.933401570959851 1.198606689440111 0.38329614841811155 0.16727984531619575 0.23825684392551924 8.650797799731883 0.05528675229140075 0.05522886386713239 2.386050060106909e-07 6.622320448930502 0.26520511848026007 TYSAPAINAIQGGSFES(ph)PKKEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TYSAPAINAIQGGSFESPKKEK 22 2 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3 Q9H4L5-5 OSBPL3 Oxysterol-binding protein-related protein 3 1 TYSAPAINAIQGGS(0.008)FES(0.992)PKKEK 87.228 7.0107e-05 7730700.0 54494.0 38568.0 41180.0 63675.0 69155.0 51533.0 53022.0 72189.0 42878.0 44904.0 True False 63718.75789443933 42396.77615296774 42161.88737601966 60107.496187135344 55604.57418332126 48830.51876133828 47999.37231396269 70294.11524056786 43505.0096327936 53044.739740131576 1.2012267042236464 0.7992644767543651 0.7948363510231652 1.1331471599560015 1.0482580262572767 0.9205534611077566 0.9048846794067356 1.325185411125433 0.820156906149912 1.0 15.694922070800738 -5.767192629984864 24.999174603073303 1.027309920364326 0.9185247120699511 0.05488808447308946 0.16728882906404333 365.92370751494644 1590028.8201734023 0.045933197950604784 0.07024247468151042 1.7092570112283784e-06 5.767192629984864 -0.10878520829437477 TYSLGSALRPSTSR ddPTM_PC-9_Lapatinib_30min_R1 1 TYSLGSALRPSTSR 14 1 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 0 96.23 0.0038905000000000003 12464000.0 21349.0 22863.0 23587.0 33307.0 25368.0 18949.0 19929.0 20209.0 18124.0 19727.0 False True 21044.559345072903 22810.06212819854 21647.767908453006 35756.50788889488 23875.904115406924 18138.595442276448 20960.826106654098 21147.98391658164 16082.684265819062 23136.785665424784 0.9095714352630033 0.9858786115776448 0.9356428425925671 1.5454397341947455 1.0319455978315373 0.7839721430873803 0.905952382917978 0.9140415709596525 0.6951131630117813 1.0 14.497900827976661 -6.618159360606673 6.160399167622381 0.8592120463508636 1.1002184753172002 0.27375477824132644 0.18244831975978693 0.2953297343622244 15.929791436299439 0.06311855323916785 0.0630430202571849 2.409021296939715e-07 6.618159360606673 0.24100642896633662 TYSS(ph)PGSFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TYSSPGSFK 9 0 Q8N3Z6 Q8N3Z6 ZCCHC7 Zinc finger CCHC domain-containing protein 7 1 TYS(0.005)S(0.994)PGS(0.001)FK 75.509 0.025868000000000002 11208000.0 77005.0 71263.0 70989.0 95026.0 85817.0 79774.0 95797.0 94746.0 83007.0 57291.0 True False 90040.4255819226 78337.5196792401 72681.64698728186 89702.0012984489 69001.77489248922 75590.51100589908 86722.41464978081 92259.01789168503 84220.82034118415 67677.40478469341 1.330435554796673 1.1575136477005938 1.073942584212689 1.325435004250293 1.0195688666255616 1.1169239016534418 1.2814086906209916 1.3632174310642484 1.2444451823931695 1.0 16.046386626257323 -7.269747432834225 24.572154937288094 1.2525359461263204 1.1658144896663547 0.015778463872324844 0.12719674628084127 1269.2675098820264 3754009.514636088 0.05127851723368318 0.03524984183836591 5.373442020126767e-08 7.269747432834225 -0.08672145645996565 TYSVEYLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 TYSVEYLPK 9 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 99.802 0.01854 1877300.0 15337.0 13479.0 14349.0 12526.0 14138.0 14694.0 18842.0 16612.0 12538.0 15147.0 False True 17933.251180442192 14817.106040392344 14691.134578885541 11824.208829839929 11367.760390482192 13923.420772691377 17057.149355733196 16175.952601868907 12721.344530434395 17893.031196413976 1.0022478015930736 0.828093679474605 0.8210534267569968 0.6608275981885994 0.6353177539175395 0.7781476832992854 0.9532845032512823 0.9040364611397315 0.7109664310529977 1.0 14.12711018961106 -9.912182561749653 13.86097279661981 0.999999999999997 0.807726091825011 0.19834766512357171 0.11420823396100416 0.0 0.0 0.11964250386999319 0.029017569457020692 1.224101522929274e-10 9.912182561749653 -0.19227390817498602 TYSVEYLPK ddPTM_PC-9_Lapatinib_30min_R1 2 TYSVEYLPK 9 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 138.1 0.004181300000000001 11414800.0 93794.0 98744.0 100609.0 92767.0 97478.0 85993.0 101331.0 78904.0 84564.0 86325.0 False True 92456.4803602869 98515.36433481309 92337.31638197077 99589.39464163998 91744.53568912165 82315.27984947372 106577.42336360915 82570.16789321374 75039.51182160244 101246.16122916785 0.9131850456138703 0.9730281438703273 0.9120080728094752 0.9836362527979918 0.906153226703188 0.8130212429798241 1.052656437238881 0.8155387512057715 0.7411590811008885 1.0 16.627507683366105 -6.865483464115651 0.8658583734343692 0.8689297415083855 0.9451862265492704 0.0650830863376698 0.08898678792806017 1.5516638839214636 2.4892179976694537 0.05978948411487324 0.05027154793855932 1.3630649042987855e-07 6.865483464115651 0.07625648504088489 TYSYLTPDLWK ddPTM_PC-9_Lapatinib_30min_R1 2 TYSYLTPDLWK 11 0 H0YEN5;P15880;E9PQD7 H0YEN5 RPS2 40S ribosomal protein S2 0 ; 171.85 0.0015215 13429200.0 106189.0 108319.0 106917.0 89990.0 107425.0 111677.0 116093.0 93173.0 87141.0 103020.0 False True 104674.72538732251 108068.19401059963 98126.69697155534 96608.16479783962 101106.47270567618 106900.83504180207 122103.72749258822 97502.15772475947 77326.26294458946 120826.86973447865 0.8663199304703412 0.894405311070984 0.8121264515682005 0.7995586164744606 0.836787983731278 0.884743892453065 1.0105676639717267 0.8069575744122474 0.6399757199248535 1.0 16.882581794348646 -10.654379400221046 4.6964943177416165 1.0000129997964513 0.8441022625342792 0.22726039060828074 0.08859681385016877 1.2561790093341653e-05 2.3229946470696975e-06 0.08935579627742216 0.021670157204888022 2.2162594467334543e-11 10.654379400221046 -0.15591073726217208 TYT(ph)HEVVTLWYR ddPTM_PC-9_AZD4547_30min_R2 2 TYTHEVVTLWYR 12 0 G3V5T9;P24941;Q00526;K7EJ83 G3V5T9 CDK2;CDK3 Cyclin-dependent kinase 2;Cyclin-dependent kinase 3 1 T(0.092)YT(0.908)HEVVTLWYR;T(0.027)YT(0.973)HEVVTLWYR 122.1 0.00087351 15599800.0 31750.0 33857.0 36723.0 46186.0 37669.0 37395.0 43315.0 37418.0 34224.0 41359.0 True False 41845.839558974345 44800.61314027934 36236.02902561804 35538.53126658679 32439.30956426995 35056.68473848705 47169.951087726375 31635.90788010065 36033.01077031925 39911.03399869984 1.0484779612659882 1.1225119635271485 0.9079200761072359 0.8904437621872816 0.8127905071396224 0.8783707467871936 1.181877449961908 0.7926606933093049 0.9028333059848331 1.0 15.28450003563423 -5.267453997269558 24.668792803409342 0.9163154508935506 1.0854949677075396 0.28452204034066453 0.10422864715821206 456.744898796353 1873335.5273007813 0.027658386046264874 0.0601321661957036 5.401893313979364e-06 5.267453997269558 0.16917951681398902 TYT(ph)HEVVTLWYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 TYTHEVVTLWYR 12 0 G3V5T9;P24941;Q00526;K7EJ83 G3V5T9 CDK2;CDK3 Cyclin-dependent kinase 2;Cyclin-dependent kinase 3 1 T(0.195)Y(0.004)T(0.801)HEVVTLWYR;T(0.157)Y(0.002)T(0.841)HEVVTLWYR;T(0.159)YT(0.841)HEVVTLWYR 138.31 0.00014474 24653100.0 48027.5 48017.1 43841.2 46235.1 52408.5 46599.7 53214.4 50532.9 43034.6 38639.0 True False 56157.607163636065 52783.92035404136 44886.54047667688 43644.69724321665 42139.43064256514 44155.92969791657 48173.54679310734 49206.464919033315 43663.899611535526 45643.944833844274 1.2303407903954013 1.1564276608033865 0.983406246766695 0.9561990621558807 0.9232206111010678 0.9673995063015595 1.0554203184775433 1.078050223269648 0.956619761295466 1.0 15.478135863250607 -5.14188370016888 3.221869733483115 0.9902788217457116 1.2195124033444886 0.7739501202481558 0.04467513908848809 0.12929821222105528 2.455214600802846 0.013368453389960016 0.04630484749968042 7.213006105986038e-06 5.14188370016888 0.22923358159877705 TYT(ph)HEVVTLWYR ddPTM_PC-9_Lapatinib_30min_R1 2 TYTHEVVTLWYR 12 0 G3V5T9;P24941;Q00526;K7EJ83 G3V5T9 CDK2;CDK3 Cyclin-dependent kinase 2;Cyclin-dependent kinase 3 1 T(0.019)YT(0.981)HEVVTLWYR;T(0.238)Y(0.004)T(0.758)HEVVTLWYR 123.68 0.00072305 16989000.0 34914.0 42246.0 41719.0 41232.0 40345.0 44198.0 40299.0 37424.0 40041.0 30735.0 True False 34416.11995755654 42148.18198258652 38289.024859997066 44264.33882591985 37971.98642132186 42307.75457057021 42385.48503547862 39162.85566302893 35531.160929577396 36047.503798186786 0.9547435004164614 1.1692399623162422 1.0621824211285062 1.227944633107893 1.053387403297309 1.1736666929125428 1.17582302710266 1.0864235116607117 0.9856760437144232 1.0 15.137611739357759 -8.158882424596863 3.9509911795352783 0.9926288585852189 1.121172060615283 0.2972919693046506 0.07453897530170141 0.2670039007622777 7.096682543455614 0.05455441476975191 0.01835729503443188 6.936135607757444e-09 8.158882424596863 0.1285432020300642 TYTVS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 TYTVSPR 7 0 Q7Z2K8;Q7Z2K8-2 Q7Z2K8 GPRIN1 G protein-regulated inducer of neurite outgrowth 1 1 TYT(0.009)VS(0.991)PR 75.738 0.03228 6343100.0 17777.0 29101.0 33192.0 41037.0 33459.0 24754.0 27302.0 35414.0 28086.0 22263.0 True False 23429.71621542953 38507.329148928395 32751.85239273248 31576.55366532982 28813.7953943802 23206.128466813963 29731.825109017765 29941.58003276189 29570.56862129457 21483.579146329816 1.090587190143882 1.792407535385316 1.5245063296786698 1.469799489659257 1.3412008864129445 1.080179811229379 1.3839325796929445 1.3936960796347106 1.3764265451246427 1.0 14.39094674468421 -6.312474794318302 3.612713308286956 1.2747353423562717 1.4990231437291102 0.20099268627584632 0.20121851243496985 0.3826975988146131 10.25422646566186 0.06280863339570297 0.07446190736000581 4.86995788717775e-07 6.312474794318302 0.22428780137283844 TYTVS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 TYTVSPR 7 0 Q7Z2K8;Q7Z2K8-2 Q7Z2K8 GPRIN1 G protein-regulated inducer of neurite outgrowth 1 1 TYT(0.004)VS(0.996)PR 77.318 0.02997 5628800.0 53310.0 48137.0 30763.0 28925.0 30233.0 22097.0 19868.0 18585.0 32802.0 19041.0 True False 52549.78962414329 48025.54173402846 28233.78488861407 31052.24099097139 28454.75438036496 21151.962820622863 20896.667825129374 19448.526947878163 29107.493339626828 22332.211479462327 2.3530938560415464 2.150505415829276 1.264262830153614 1.3904686967311044 1.2741574835314984 0.9471503903711072 0.935718696930076 0.8708733107674479 1.3033860693283934 1.0 14.44683850274193 -4.938702997606712 0.8142524179248577 1.0175453474127283 3.0651802128716814 0.8847753150852138 0.1645494211916118 0.629617701558635 0.3754614719501403 0.06408853010742269 1.1177344667115745 1.1515876597509777e-05 4.938702997606712 2.047634865458953 up TYVDLTNEETTDSTT(ph)SK ddPTM_PC-9_Lapatinib_30min_R1 1 TYVDLTNEETTDSTTSK 17 0 O95551;O95551-2 O95551 TDP2 Tyrosyl-DNA phosphodiesterase 2 1 TYVDLTNEET(0.001)T(0.029)DS(0.233)T(0.264)T(0.406)S(0.068)K 104.44 0.0019276 3428400.0 13142.0 12860.0 12640.0 10466.0 11926.0 9515.3 10000.0 10785.0 8540.6 5501.1 True False 12954.59267005237 12830.223460116038 11600.787991811003 11235.704553552525 11224.536127418134 9108.352800247674 10517.751069624208 11286.110472578212 7578.667691494937 6451.957805245009 2.007854524330763 1.98857832729252 1.7980260165961317 1.7414411086846617 1.7397100951734896 1.411719213793245 1.6301642675148902 1.7492536084788652 1.1746306966443563 1.0 12.655521288195501 -3.497068331764159 0.06388334890065948 2.526317312749172e-10 4.335659255233728 0.8107392214825712 0.13687047268197416 87.12539936486694 0.6210736455633531 10.733458789892694 38.87539313261738 0.00031836965604500254 3.497068331764159 4.335659254981096 up VAAAAGSGPS(ph)PPGSPGHDR ddPTM_PC-9_AZD4547_30min_R2 2 VAAAAGSGPSPPGSPGHDR 19 0 Q9BTU6 Q9BTU6 PI4K2A Phosphatidylinositol 4-kinase type 2-alpha 1 VAAAAGS(0.079)GPS(0.921)PPGS(0.001)PGHDR;VAAAAGS(0.001)GPS(0.999)PPGS(0.001)PGHDR 84.03 0.0047313 0.0 9715.2 17611.199999999997 39285.0 48866.0 36869.0 36792.0 27143.0 51627.0 31670.0 40050.0 True False 12804.431511286548 23303.675994213514 38764.055231636994 37600.69867217405 31750.37575526478 34491.390423811084 29558.67441704158 43649.23342043818 33344.01154441356 38647.86169027124 0.33131021876198097 0.60297452368703 1.0030064675323294 0.9729050205548424 0.8215299467203705 0.8924527493973501 0.7648204357055629 1.1294087566926354 0.8627647193429899 1.0 15.2381009744452 -5.012837124245652 2.9366326387683452 0.9252292214832245 0.33621988903035266 0.7882627214452752 0.10057874442632479 0.12104297743997319 1.9588527113713534 0.02642301765803502 0.13062037607713367 9.708740109870097e-06 5.012837124245652 -0.5890093324528718 down VAAAAGSGPS(ph)PPGSPGHDR ddPTM_PC-9_Lapatinib_30min_R1 1 VAAAAGSGPSPPGSPGHDR 19 0 Q9BTU6 Q9BTU6 PI4K2A Phosphatidylinositol 4-kinase type 2-alpha 1 VAAAAGS(0.003)GPS(0.996)PPGS(0.001)PGHDR 89.631 0.00059234 5479700.0 13061.0 12645.0 21164.0 10860.0 14363.0 16034.0 10178.0 13187.0 19156.0 10744.0 True False 12874.747744905944 12615.721279406482 19423.977615402542 11658.680627897984 13518.19657874448 15348.263197079557 10704.96703866352 13799.716161510321 16998.44955837727 12601.086084519893 1.0217173074249717 1.00116142329228 1.5414526561535353 0.925212362624867 1.0727802737060288 1.218011137622058 0.8495273317602595 1.095121172012539 1.3489670211252205 1.0 13.621260464165436 VAADLQLST(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 2 VAADLQLSTPQK 12 0 Q9H582-2;Q9H582 Q9H582-2 ZNF644 Zinc finger protein 644 1 VAADLQLS(0.002)T(0.998)PQK;VAADLQLS(0.05)T(0.95)PQK 201.09 8.9674e-06 9135000.0 103069.0 99191.0 134657.0 180328.0 175617.0 159744.0 120265.0 145986.0 128649.0 156930.0 True False 135842.79803161955 131252.55096427462 132871.3601966793 138756.16563982717 151235.61092007713 149755.1824271927 130968.35201582378 123427.21812454908 135449.12349786106 151435.92846577417 0.8970314997759676 0.866720020103676 0.8774097503995519 0.9162697851533117 0.9986772125497133 0.9889012729303447 0.8648433257727459 0.8150458043544448 0.8944318885889337 1.0 17.208348002548277 -5.785354001866334 6.463629575857671 0.9210798196241186 0.8789076845325764 0.11298589608717713 0.05697178850814148 0.4501855537950569 64.7390150138991 0.018000517350798204 0.027891007658866266 1.6392530414866413e-06 5.785354001866334 -0.04217213509154216 VAADLQLST(ph)PQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VAADLQLSTPQK 12 0 Q9H582-2;Q9H582 Q9H582-2 ZNF644 Zinc finger protein 644 1 VAADLQLS(0.278)T(0.722)PQK;VAADLQLS(0.095)T(0.905)PQK 143.76 0.00017526 8556000.0 75025.0 71403.0 83909.0 90741.0 99563.0 86459.0 83150.0 90175.0 77070.0 63463.0 True False 87725.25068870523 78491.41795401233 85909.70878665458 85657.07595629142 80054.34486897576 81924.93783762926 75273.43004613167 87808.00179831013 78197.00294788482 74968.3395271684 1.1701639817821194 1.0469942171463884 1.1459465332765046 1.142576672986727 1.0678420433730456 1.0927938160873871 1.0040695915220679 1.1712677958738655 1.0430670259082684 1.0 16.19399382781435 -6.274852990789876 23.457994517432482 1.070262593945712 1.1221417822446673 0.23693995517198285 0.05450784412344644 601.7228301468774 1052302.8045581223 0.01621050019811452 0.018510521640382353 5.310641796794086e-07 6.274852990789876 0.051879188298955325 VAADLQLST(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 2 VAADLQLSTPQK 12 0 Q9H582-2;Q9H582 Q9H582-2 ZNF644 Zinc finger protein 644 1 VAADLQLS(0.009)T(0.991)PQK;VAADLQLS(0.001)T(0.999)PQK 160.18 0.00014123 10989600.0 77811.0 73415.0 81142.0 69201.0 66308.0 68575.0 58293.0 57005.0 73708.0 50757.0 True False 76701.40087121009 73245.01207810428 74470.81797717774 74290.27238776867 62407.893806543834 65642.20710613273 61311.126310160456 59653.66040698387 65406.228860350435 59530.279820548785 1.2884434795607016 1.230382459126648 1.250973759936397 1.2479409237066108 1.0483386605046958 1.1026692181526454 1.029914969238847 1.0020725685618648 1.0987052145146037 1.0 15.861336055282337 -6.257782734827526 6.900962455568505 1.0486977169010392 1.2529758187515225 0.8951664387536138 0.034782334589214564 0.04154464099376286 12.927356741070106 0.010454602402927211 0.01276606360405267 5.523536970117519e-07 6.257782734827526 0.20427810185048334 VAAETQS(ph)PSLFGSTK ddPTM_PC-9_AZD4547_30min_R2 1 VAAETQSPSLFGSTK 15 0 Q9UKX7-2;Q9UKX7 Q9UKX7-2 NUP50 Nuclear pore complex protein Nup50 1 VAAET(0.053)QS(0.915)PS(0.03)LFGS(0.002)TK 77.74600000000001 0.012606000000000001 7074700.0 23337.0 25059.0 23765.0 30867.0 22040.0 24414.0 23198.0 28309.0 21064.0 18446.0 True False 30757.6805602452 33158.831694546454 23449.860572224843 23751.09004039609 18980.126438092582 22887.38872056219 25262.577059519244 23934.494526104252 22177.4000369917 17800.211154525437 1.7279390841622415 1.8628336151010387 1.3173922696003 1.3343150726814683 1.0662865891490938 1.2857931022207798 1.4192290664538894 1.3446185732476137 1.2459065706843275 1.0 14.119606734773699 -5.305397530216114 5.492065885063527 1.2648079620079162 1.796509186277515 0.7511845055124473 0.12508505983728127 0.08663159540833199 6.663961942802238 0.03287906432799706 0.0725603261800775 4.949968893805828e-06 5.305397530216114 0.5317012242695989 VAAETQS(ph)PSLFGSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VAAETQSPSLFGSTK 15 0 Q9UKX7-2;Q9UKX7 Q9UKX7-2 NUP50 Nuclear pore complex protein Nup50 1 VAAET(0.199)QS(0.644)PS(0.156)LFGSTK;VAAET(0.04)QS(0.955)PS(0.005)LFGSTK 182.91 2.4729e-06 26306200.0 44665.0 53195.0 49472.0 41336.0 53573.0 53157.0 75387.0 55349.0 56387.0 40359.0 True False 52225.90232603837 58475.848046492356 50651.600103604826 39020.07793312018 43075.75522699832 50369.353342449635 68245.79760538472 53896.14739711306 57211.55320127646 47675.76721833177 1.095439158574401 1.2265318726534904 1.0624181436167601 0.8184467751599517 0.903514672972799 1.0564980131684625 1.4314567250245234 1.1304725763571877 1.200013267521746 1.0 15.540968534724637 -7.024787063380038 24.55170879703651 1.2074468099241091 1.019323045152777 0.23892750559671383 0.14266888747703257 861.1095389196225 852930.432334771 0.05763371154439898 0.04487264710083308 9.445238672523088e-08 7.024787063380038 -0.18812376477133208 VAAETQS(ph)PSLFGSTK ddPTM_PC-9_Lapatinib_30min_R1 2 VAAETQSPSLFGSTK 15 0 Q9UKX7-2;Q9UKX7 Q9UKX7-2 NUP50 Nuclear pore complex protein Nup50 1 VAAET(0.114)QS(0.773)PS(0.114)LFGSTK;VAAET(0.055)QS(0.754)PS(0.188)LFGS(0.003)T(0.001)K 144.33 0.00010537 40617800.0 28329.0 36074.0 36145.0 29148.0 49371.0 64285.0 72639.0 75662.0 57803.0 59227.0 True False 27925.023265097665 35990.47286937996 33173.29762373484 31291.641154877565 46467.094847120636 61535.68040565418 76399.89199464336 79177.53273771102 51292.61744742542 69464.30803498314 0.40200534713502445 0.5181146100419611 0.4775588868894847 0.4504707819031132 0.6689348265546559 0.8858604101355764 1.0998438501131742 1.1398304392211922 0.738402481769397 1.0 16.08398426605373 -6.663668814754611 2.0858282675322126 1.0055164891203368 0.4665497133471204 0.8429605375569837 0.1048029331889397 0.11634241416211086 1.0372684804859134 0.04003542902203764 0.03932362278746459 2.1693577878590143e-07 6.663668814754611 -0.5389667757732164 down VAAETQSPS(ph)LFGSTK ddPTM_PC-9_AZD4547_30min_R2 2 VAAETQSPSLFGSTK 15 0 Q9UKX7-2;Q9UKX7 Q9UKX7-2 NUP50 Nuclear pore complex protein Nup50 1 VAAET(0.003)QS(0.363)PS(0.634)LFGSTK;VAAET(0.005)QS(0.12)PS(0.874)LFGSTK 129.05 1.6225e-05 94235000.0 110863.0 107946.0 115893.0 114067.0 84209.0 111304.0 86830.0 107053.0 85151.0 74339.0 True False 146115.12790634885 142837.43350091833 114356.1830968589 87770.61546758219 72518.03390314612 104344.14328473229 94557.70178800148 90510.41868321184 89651.90802078819 71736.4142370307 2.036833447286016 1.991142643803695 1.5941162422616277 1.2235155102340558 1.010895716972036 1.4545491908747974 1.3181269623480891 1.2617081526287093 1.2497405811860252 1.0 16.130418013167407 -5.46581999901035 2.369794959949372 1.2325179873677587 2.033436823762952 0.8604153277335977 0.12859145144939121 0.10607455942465871 1.157567624574407 0.03736422322361319 0.09477082364829002 3.421212112882076e-06 5.46581999901035 0.8009188363951933 VAAETQSPS(ph)LFGSTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VAAETQSPSLFGSTK 15 0 Q9UKX7-2;Q9UKX7 Q9UKX7-2 NUP50 Nuclear pore complex protein Nup50 1 VAAETQS(0.044)PS(0.956)LFGSTK 208.49 4.564e-13 18764000.0 27041.0 36496.0 27710.0 29046.0 40532.0 33463.0 55405.0 32994.0 38993.0 26055.0 True False 31618.50721590512 40119.08168633869 28370.711490760215 27418.64678840256 32590.045561396517 31708.141371755224 50156.637302536736 32127.942460032686 39563.19885749148 30778.56524873349 1.0272898349999013 1.3034747189195104 0.9217684860059435 0.8908357672562666 1.0588552552084138 1.0302020615811514 1.629596340739133 1.0438414591581628 1.2854140060709773 1.0 14.90963836115771 VAAETQSPS(ph)LFGSTK ddPTM_PC-9_Lapatinib_30min_R1 2 VAAETQSPSLFGSTK 15 0 Q9UKX7-2;Q9UKX7 Q9UKX7-2 NUP50 Nuclear pore complex protein Nup50 1 VAAETQS(0.009)PS(0.99)LFGSTK;VAAETQS(0.243)PS(0.757)LFGSTK 257.72 4.3294e-50 38028000.0 58756.0 108425.0 129543.0 110874.0 150632.0 200042.0 279250.0 232410.0 217955.0 182799.0 True False 57918.12866546927 108173.94857411203 118892.47459044092 119028.04382482126 141772.12191390633 191486.66998067783 293708.1986192561 243208.61705441878 193406.61273210085 214395.56358564275 0.2701461154177904 0.5045531109178045 0.554547270484671 0.5551796027592434 0.661264251661037 0.8931466061058969 1.3699359898458485 1.1343920227960609 0.902101748270749 1.0 17.70991552734438 -6.735487373784932 1.9987256544868284 1.1146357988911353 0.4803720736794465 0.808801014351657 0.13833123345800524 0.14002781240577375 1.1521327950051694 0.05720102339398581 0.05347565048014959 1.8387074097072282e-07 6.735487373784932 -0.6342637252116887 down VAAPQDGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 VAAPQDGSPR 10 0 Q9HD15 Q9HD15 SRA1 Steroid receptor RNA activator 1 1 VAAPQDGS(1)PR 67.87899999999999 0.042445 9858600.0 30044.0 35489.0 46210.0 37047.0 34886.0 31824.0 31972.0 32145.0 31692.0 26556.0 True False 29615.567050605172 35406.82740093767 42410.792175758404 39771.55996516915 32834.07406851491 30462.961705367346 33627.35371980254 33638.57405109193 28122.513228445034 31146.169216354236 0.9508574503940801 1.1367955768488616 1.3616696127589694 1.276932636206378 1.0541930161759472 0.9780644770070744 1.079662589842525 1.0800228373969336 0.9029204533339034 1.0 14.92676711126016 -6.42034842493727 5.929700224828873 1.0174361961151577 1.1904227138751415 0.3578889612900392 0.1095180536377333 0.2826321582820172 13.65922581264042 0.03674140678310218 0.04156654230437623 3.7988450102850145e-07 6.42034842493727 0.17298651775998386 VAASPKS(ph)PTAALNESLVECPK ddPTM_PC-9_AZD4547_30min_R2 1 VAASPKSPTAALNESLVECPK 21 1 Q53EZ4 Q53EZ4 CEP55 Centrosomal protein of 55 kDa 1 VAAS(0.013)PKS(0.805)PT(0.182)AALNESLVECPK 71.842 0.0010812 11818000.0 22212.0 7105.0 25925.0 56642.0 45153.0 23784.0 14458.0 18862.0 19687.0 31263.0 True False 29274.95396169884 9401.552304152303 25581.21756090593 43584.06201017643 38884.28534751335 22296.782720154457 15744.733991142739 15947.311305640556 20727.614628192918 30168.4918857166 0.970381750357206 0.3116348122328086 0.8479448577612679 1.4446881261178153 1.2889038502426196 0.7390751518046867 0.5218933067912868 0.5286081706056668 0.687061677020935 1.0 14.880754957924042 -6.985254175714471 24.682021298769104 0.6430189463800702 0.9611454043235881 0.167114799909297 0.30547329288941344 380.27481932723873 636512.9719699877 0.11946502852368976 0.10531675453444349 1.0345365153705663e-07 6.985254175714471 0.3181264579435179 VAASPKSPT(ph)AALNESLVECPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VAASPKSPTAALNESLVECPK 21 1 Q53EZ4 Q53EZ4 CEP55 Centrosomal protein of 55 kDa 1 VAAS(0.009)PKS(0.264)PT(0.706)AALNES(0.021)LVECPK 53.188 0.018158 3629700.0 10873.0 4386.8 6014.9 11443.0 15709.0 22197.0 18016.0 35387.0 20318.0 13535.0 True False 12713.584148461101 4822.292512648796 6158.3180276352805 10801.885808706556 12630.934218000059 21032.95024441476 16309.394055455317 34458.128745625756 20615.112312120444 15988.788356998944 0.795156197242166 0.3016046247518113 0.38516477234746394 0.6755912685515116 0.7899869543567374 1.3154811843642786 1.0200519070800027 2.1551432151231165 1.2893480013509822 1.0 13.964772993941123 -6.705187963891814 1.3101494302143457 1.4825768195056392 0.4824100614019628 0.5835708412290911 0.3269943171040335 0.27501243620196864 0.9907392555170527 0.14918797975164957 0.1416627999144515 1.971569250631581e-07 6.705187963891814 -1.0001667581036764 VACETVAK ddPTM_PC-9_Lapatinib_30min_R1 2 VACETVAK 8 0 P31153 P31153 MAT2A S-adenosylmethionine synthase isoform type-2 0 ; 98.458 0.025341 5292800.0 33452.0 26786.0 36060.0 33766.0 36179.0 29980.0 30310.0 26451.0 27137.0 26410.0 False True 32974.9683456545 26723.978662726942 33095.28599562537 36249.264280073985 34051.022350650725 28697.825286793384 31879.303492031 27680.010024122956 24080.54529472147 30974.93331088703 1.0645694702453 0.8627614592259358 1.0684538256614446 1.1702773954749126 1.0993089802289426 0.9264854583789115 1.0291968402988005 0.8936261378291336 0.777420408077446 1.0 14.918813555792449 -7.788443966023937 4.617081438406239 0.8723777420772395 1.0310721516099173 0.31155366742752366 0.09550723339153787 0.23694273499068194 11.889944421690645 0.05533439972329452 0.02684583969134219 1.6276313039657302e-08 7.788443966023937 0.15869440953267777 VACIGAWHPAR ddPTM_PC-9_AZD4547_30min_R2 1 VACIGAWHPAR 11 0 P39023;G5E9G0;B5MCW2;H7C422;Q92901 P39023 RPL3;RPL3L 60S ribosomal protein L3;60S ribosomal protein L3-like 0 96.34200000000001 0.0049052 4530200.0 32273.0 31770.0 50363.0 63558.0 51978.0 55725.0 39587.0 54933.0 36228.0 41328.0 False True 42535.14267989857 42039.0312037887 49695.15371340039 48905.6850613113 44761.75190558874 52240.50694082607 43110.166309819295 46444.36708476051 38142.93811907214 39881.119299264166 1.0665483674296818 1.0541086093479917 1.2460822210252585 1.2262866720045553 1.122379529262977 1.3099057363164313 1.080966810041731 1.1645703004533636 0.9564159378991126 1.0 15.283418280379765 -8.257745763322001 24.38237066113328 0.9782079513080547 1.1617424835867034 0.4532273761062553 0.07931607676888808 192.46455510891974 1270531.9531773338 0.059961793300047674 0.020649669749417055 5.524007209042289e-09 8.257745763322001 0.1835345322786487 VACIGAWHPAR ddPTM_PC-9_Lapatinib_30min_R1 2 VACIGAWHPAR 11 0 P39023;G5E9G0;B5MCW2;H7C422;Q92901 P39023 RPL3;RPL3L 60S ribosomal protein L3;60S ribosomal protein L3-like 0 ; 125.71 0.00037536 10708400.0 80537.0 87756.0 90180.0 87397.0 90450.0 80093.0 75197.0 65809.0 81090.0 75038.0 False True 79388.5276113231 87552.80637371242 82765.7485048668 93824.46692784525 85129.9088315421 76667.60909590214 79090.33271825318 68866.72638756585 71956.79028444424 88008.21831815016 0.9020581160310865 0.9948253475284384 0.9404320424448112 1.0660875622850279 0.9672949919721933 0.8711414747512367 0.8986698541304543 0.7825033582501612 0.8176144416913439 1.0 16.42535063026795 -6.762611517835992 4.391299631519899 0.8604977979666856 0.9796422564064354 0.35490414503943724 0.06641748285698058 0.19904443678980221 9.176301436448036 0.023049888298695857 0.021537352872698104 1.7273823675081483e-07 6.762611517835992 0.11914445843974986 VADIGLAAWGR ddPTM_PC-9_Lapatinib_30min_R1 1 VADIGLAAWGR 11 0 P23526 P23526 AHCY Adenosylhomocysteinase 0 97.565 0.024593 2971800.0 15484.0 13965.0 21846.0 15650.0 16171.0 16870.0 15370.0 14921.0 18466.0 15557.0 False True 15263.195320582168 13932.664900507043 20049.90620799867 16800.95320686957 15219.853573409233 16148.50942589075 16165.783394012411 15614.28413178854 16386.164624399404 18246.006721600508 0.8365225089231638 0.7636007764928026 1.098865440198628 0.920801656122366 0.83414709890418 0.8850434877223498 0.8859902136764299 0.8557644623304667 0.8980685403892057 1.0 14.155293133222848 -8.573868118877034 18.911591479539727 1.0000000020197937 0.8870152722317803 0.14765707788686822 0.08220660922673105 2704.6769776141678 1003146.7736864063 0.08167325830928764 0.021087944617073428 2.667668625819003e-09 8.573868118877034 -0.11298472978801333 VADNS(ph)FDAK ddPTM_PC-9_AZD4547_30min_R2 4 VADNSFDAK 9 0 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 VADNS(1)FDAK;VADNS(1)FDAK;VADNS(1)FDAK;VADNS(1)FDAK 115.92 0.0019497 75842300.0 349212.0 352216.0 380911.0 458785.0 430187.0 437088.0 413390.0 424972.0 375212.0 404805.0 True False 460254.1519391681 466062.93404071894 375859.8712571743 353019.20640759147 370462.9606181362 409756.81826382794 450180.909157456 359302.34228505276 395044.94030952005 390632.90016305214 1.178226800013659 1.193096981452873 0.9621818108517959 0.9037108913771459 0.9483659990326035 1.0489562402265487 1.1524398200191235 0.9197953939237533 1.0112945943483673 1.0 18.57545393647056 -5.257080690039787 24.705863070316507 0.9933393764348771 1.1856619182991646 0.5663152898614443 0.06731930434863224 236.55855921515897 1340842.778819424 0.01882110152942777 0.04627164774081975 5.532473087046269e-06 5.257080690039787 0.19232254186428743 VADNS(ph)FDAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VADNSFDAK 9 0 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 VADNS(1)FDAK;VADNS(1)FDAK;VADNS(1)FDAK 109.16 0.0023874 34635000.0 186626.0 237216.0 229741.0 245704.0 281138.0 228995.0 270546.0 239856.0 224472.0 172952.0 True False 218218.09576848164 260765.23677407185 235218.89673759445 231938.00146311603 226051.02706601907 216986.099077342 244917.92429658206 233560.03414843892 227754.47834069777 204306.8285127216 1.0680900748987634 1.276341269023393 1.1513021784435757 1.1352435116904274 1.1064291326510582 1.062059945117453 1.198775029104481 1.1431827112616346 1.1147668435688929 1.0 17.64037789826716 -14.52287874527287 0.207876748141156 0.3277586334523581 1.1628944290473884 0.33861079044728704 0.059063632836172324 169.02611796200122 1.678087652094644 47.34017936572823 0.13006380971755088 3.000000000051587e-15 14.52287874527287 0.8351357955950303 VADNS(ph)FDAK ddPTM_PC-9_Lapatinib_30min_R1 4 VADNSFDAK 9 0 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 VADNS(1)FDAK;VADNS(1)FDAK;VADNS(1)FDAK;VADNS(1)FDAK 94.54700000000001 0.0057125 108027800.0 327932.0 367587.0 399700.0 399615.0 357810.0 336548.0 339232.0 337053.0 330465.0 287519.0 True False 323255.6295446362 366735.874885978 366838.20888661774 429004.0201765602 336764.3192815261 322154.6265717061 356795.773085076 352713.71285247157 293244.5517492771 337216.27605501394 0.9586003182476869 1.0875390689213003 1.0878425358886628 1.272192508604098 0.9986597421133548 0.9553353424706859 1.0580621352537203 1.045956965597145 0.8696037901249961 1.0 18.36331464540592 -6.476450712606589 24.99961152865969 0.9913825023372198 1.104047346769515 0.29593819831775514 0.08578520380971381 563.5250935971362 303435.3562964122 0.027083293001650643 0.03070848217699486 3.3384839094167027e-07 6.476450712606589 0.1126648444322953 VADNS(ph)FDAKR ddPTM_PC-9_AZD4547_30min_R2 1 VADNSFDAKR 10 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 VADNS(1)FDAKR 63.16 0.02584 28657000.0 50710.0 48899.0 62229.0 80986.0 61834.0 59173.0 52113.0 63947.0 54416.0 63753.0 True False 66834.72516647523 64704.645477937185 61403.802800293706 62315.92892122714 53249.416432532504 55472.902955755984 56750.956043742 54065.46050587411 57292.31866753421 61521.02687490296 1.0863720675920634 1.0517484633263325 0.9980945689536748 1.0129208188923853 0.8655482383415029 0.9016901338229408 0.9224643821231978 0.8788127125350326 0.9312640178134962 1.0 15.908791963716649 -5.808701677114289 1.4672285248558945 0.9110471596214168 1.0672511793637722 0.6770617129074462 0.04064168951777995 0.22287849453306477 0.9714748440920812 0.013070133392632311 0.028556778724404243 1.5534537323952683e-06 5.808701677114289 0.15620401974235543 VADNS(ph)FDAKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VADNSFDAKR 10 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 VADNS(1)FDAKR 60.657 0.030831 19757000.0 38711.0 41195.0 42954.0 49228.0 43834.0 47666.0 55550.0 49505.0 40277.0 30310.0 True False 45264.00772289871 45284.567351729536 43978.18626395214 46469.914759329346 35245.04236500187 45166.311048802716 50287.90185282766 48205.54620488325 40865.97492840214 35804.96306617203 1.264182500041829 1.264756711745185 1.2282706780809962 1.2978623849840916 0.9843619249059032 1.261453920936317 1.4044952863067992 1.346336990092502 1.1413494507137665 1.0 15.12787195851049 VADPDHDHTGFLT(ph)EY(ph)VATR ddPTM_PC-9_AZD4547_30min_R2 1 VADPDHDHTGFLTEYVATR 19 0 P28482;P28482-2 P28482 MAPK1 Mitogen-activated protein kinase 1 2 VADPDHDHT(0.256)GFLT(0.949)EY(0.778)VAT(0.018)R 104.3 0.0009807 0.0 6485.3 4988.8 5735.6 8568.3 7191.7 6823.6 4659.4 5172.6 3742.4 6082.2 True False 8547.490497380046 6601.332038698805 5659.542196425538 6593.01081391538 6193.256592778153 6396.919213304998 5074.077573546164 4373.2935245231865 3940.2156237389736 5869.264029277601 1.4563138503810136 1.1247290981917724 0.9642677801158869 1.1233113352930655 1.0552015656280553 1.0899014222899666 0.8645168369041134 0.745117872140003 0.6713304434907049 1.0 12.518963893980517 -7.292266215453236 2.2480968024861427 0.7794261620353806 1.1318773204293004 0.544643481479087 0.14184300951976278 0.24720195392826222 2.4456706857184485 0.07120661658363395 0.045320395961396795 5.101921646055131e-08 7.292266215453236 0.35245115839391983 VADPDHDHTGFLTEY(ph)VAT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 VADPDHDHTGFLTEYVATR 19 0 P28482;P28482-2 P28482 MAPK1 Mitogen-activated protein kinase 1 2 VADPDHDHT(0.01)GFLT(0.359)EY(0.736)VAT(0.896)R 69.72 0.025692000000000003 0.0 5511.7 4679.5 6229.9 7141.1 7191.4 5970.2 4016.1 6602.5 4914.5 6904.7 True False 7264.3059495180805 6192.056862389969 6147.287455455648 5494.829723895185 6192.998242599773 5596.882450213009 4373.525119783399 5582.2353353563685 5174.270436849398 6662.968554627113 1.0902506727985932 0.929324041022208 0.9226049027631462 0.8246819235067963 0.9294653264270671 0.8399983287218491 0.6563928801294123 0.8378000420668011 0.7765713427022126 1.0 12.70194936959478 -1.9379855158845158 0.5493856410692258 0.8154916959124215 8.066163340578667 0.43192909425987414 0.08673628253127748 72.96620976713356 1.0887642496420307 0.04253931557019966 603.0252431608968 0.011534917271765269 1.9379855158845158 7.250671644666245 VADPDHDHTGFLTEY(ph)VATR ddPTM_PC-9_AZD4547_30min_R2 5 VADPDHDHTGFLTEYVATR 19 0 P28482;P28482-2 P28482 MAPK1 Mitogen-activated protein kinase 1 1 VADPDHDHTGFLTEY(1)VATR;VADPDHDHTGFLTEY(1)VATR;VADPDHDHTGFLT(0.027)EY(0.971)VAT(0.002)R;VADPDHDHTGFLTEY(1)VATR;VADPDHDHTGFLT(0.014)EY(0.984)VAT(0.002)R 178.02 1.4475e-08 133078000.0 185975.0 194976.0 207763.0 335334.0 306744.0 263497.0 152419.0 252524.0 197716.0 254154.0 True False 245111.18147969304 257998.1790365098 205007.92687006737 258027.9271586547 264157.8903868543 247020.4909356102 165983.99572527243 213502.2182242383 208166.86411478595 245256.14581845695 0.999408926784362 1.05195398131831 0.8358931279211163 1.0520752754128806 1.0770694022990508 1.0071938874814548 0.6767781299480128 0.8705274948839673 0.8487732832141741 1.0 17.903929763504024 -7.196048979466617 24.99742497940502 0.8382300651373058 1.003989981387473 0.38403446236059535 0.09572443894102675 193.0546959933908 73800.71423361493 0.036033210840440484 0.027911202389691078 6.367237075473163e-08 7.196048979466617 0.16575991625016728 VADPDHDHTGFLTEY(ph)VATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VADPDHDHTGFLTEYVATR 19 0 P28482;P28482-2 P28482 MAPK1 Mitogen-activated protein kinase 1 1 VADPDHDHTGFLT(0.001)EY(0.999)VATR;VADPDHDHTGFLTEY(0.999)VATR 141.1 1.1842000000000001e-05 16834700.0 16139.8 12857.199999999999 15581.7 32851.0 76021.0 98000.0 109696.0 96250.0 85401.0 91409.0 True False 18871.94936441942 14133.577845725375 15953.226821926319 31010.464974378985 61125.230771314644 92860.70748085988 99304.8007497348 93723.53948530498 86649.82806218101 107980.72810675409 0.17477145871587244 0.13088981796596474 0.14774142665674858 0.2871851812642048 0.5660753714392792 0.8599748224428905 0.9196530018908382 0.8679654335414938 0.8024564158940983 1.0 16.720414324364604 -6.419363156622453 1.6550478224224148 0.89486177719111 0.14665264395610733 0.9775797430364968 0.05057962527894202 0.04938155627348443 0.27087371020240575 0.0192681060119426 0.02287409603768106 3.807473097126568e-07 6.419363156622453 -0.7482091332350027 down VADPDHDHTGFLTEY(ph)VATR ddPTM_PC-9_Lapatinib_30min_R1 4 VADPDHDHTGFLTEYVATR 19 0 P28482;P28482-2 P28482 MAPK1 Mitogen-activated protein kinase 1 1 VADPDHDHTGFLTEY(1)VATR;VADPDHDHTGFLTEY(1)VATR;VADPDHDHTGFLTEY(1)VATR;VADPDHDHTGFLTEY(1)VATR 186.72 2.4292e-11 58231000.0 17172.800000000003 8374.4 22852.0 30412.300000000003 118487.0 204067.0 176134.0 159287.0 245452.0 178606.0 True False 16927.91272289418 8355.0095913216 20973.19677127096 32648.921994458728 111517.82761440483 195339.5301134114 185253.3566897193 166688.05552578234 217806.61103585397 209477.80912246465 0.08081005235737311 0.03988493877381114 0.10012132960112083 0.1558586187779516 0.5323610557202716 0.932507032280504 0.88435790628981 0.7957313293664122 1.0397598292071126 1.0 17.676437895618534 -6.455820161755197 1.9464576188929565 0.9237798468870154 0.0697248425368815 0.9719803576981103 0.06693292991392268 0.05009520315610622 0.37826983350859084 0.02432112961099303 0.02764028634412922 3.5009010683118474e-07 6.455820161755197 -0.8540550043501339 down VADPDHDHTGFLTEYVAT(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 VADPDHDHTGFLTEYVATR 19 0 P28482;P28482-2 P28482 MAPK1 Mitogen-activated protein kinase 1 1 VADPDHDHT(0.001)GFLT(0.063)EY(0.191)VAT(0.745)R 78.848 0.006233399999999999 21678000.0 24105.0 29796.0 24136.0 18576.0 70117.0 96761.0 74781.0 72677.0 117640.0 81106.0 True False 23761.258279684385 29727.00919266077 22151.6312476543 19942.141007719427 65992.85591532593 92622.75759090777 78652.79427375685 76053.83874043285 104390.14439588136 95125.0640330481 0.24978966922355303 0.31250448548800025 0.2328685028790986 0.20964128865964476 0.6937483468331633 0.9736945623366836 0.8268356512898799 0.7995141923269605 1.0973989395645969 1.0 16.53753789931023 -6.420131593182865 3.1289223549848884 0.9175658909836737 0.2529119712709535 0.9330904801129792 0.0867172284012077 0.0632324660982297 1.1811213515616235 0.029059069674055058 0.03287349119126393 3.800742146733258e-07 6.420131593182865 -0.6646539197127201 down VAEAVAHFEAQRDS(ph)PPTK ddPTM_PC-9_AZD4547_30min_R2 1 VAEAVAHFEAQRDSPPTK 18 1 Q6PJ61 Q6PJ61 FBXO46 F-box only protein 46 1 VAEAVAHFEAQRDS(0.682)PPT(0.318)K 50.188 0.029772000000000003 3644900.0 19510.0 16754.0 22319.0 26245.0 23982.0 19112.0 19168.0 24956.0 18831.0 22369.0 True False 25713.774166790223 22169.402857673165 22023.035477024456 20194.620731207953 20652.513259452655 17916.923618718145 20873.91486666372 21099.623631829385 19826.36821575156 21585.8681185937 1.191231875665951 1.027033183741951 1.0202524798182284 0.9355482309193139 0.9567608375065968 0.8300302549928401 0.9670176224547247 0.977473943410899 0.9184883418551727 1.0 14.397799494364346 -4.050693986957031 0.864428763171711 0.9365653183364621 1.8281879376835253 0.723189411903661 0.0463948234496372 3.6344890257384996 0.8507096556275834 0.01618804369697324 4.156939817872026 8.898278884939167e-05 4.050693986957031 0.8916226193470632 VAEAVAHFEAQRDS(ph)PPTK ddPTM_PC-9_Lapatinib_30min_R1 2 VAEAVAHFEAQRDSPPTK 18 1 Q6PJ61 Q6PJ61 FBXO46 F-box only protein 46 1 VAEAVAHFEAQRDS(0.709)PPT(0.291)K;VAEAVAHFEAQRDS(0.71)PPT(0.29)K 48.623000000000005 0.034333999999999996 7820800.0 60722.0 42565.0 50086.0 48547.0 50413.0 55434.0 44234.0 46328.0 52653.0 41652.0 True False 59856.09314494902 42466.443357685814 45968.12241755107 52117.308328044535 47447.80645577146 53063.21704296546 46524.22008137575 48480.568008678994 46722.66467932968 48851.49270219863 1.225266411199245 0.869296740154156 0.940976823324013 1.0668519106622698 0.9712662567962024 1.0862148546092896 0.9523602557037497 0.992407096016885 0.9564224570199645 1.0 15.576115025287795 -4.74318020770578 24.94504106583814 0.984920832440005 1.2252671954907368 0.6061647452581889 0.05883487944715836 834.0473814997188 1139385.1329319377 0.014780279154500907 0.48395842767379826 1.8064244062713204e-05 4.74318020770578 0.24034636305073187 VAEDEAEAAAAAK ddPTM_PC-9_Lapatinib_30min_R1 1 VAEDEAEAAAAAK 13 0 F5GZS6;J3KPF3;P08195-2;P08195-3;P08195;P08195-4;F5H0E2;H0YFS2;F5H867 F5GZS6 SLC3A2 4F2 cell-surface antigen heavy chain 0 112.83 0.0018965 2776100.0 14986.0 13815.0 12171.0 9832.2 16564.0 8996.8 15926.0 12521.0 17957.0 13825.0 False True 14772.296891904189 13783.012216291072 11170.34736141865 10555.292787257695 15589.738086076977 8612.027836565141 16750.57035348353 13102.771370157781 15934.493564407028 16214.632829345437 0.9110472649845706 0.8500354193248466 0.6889053535151546 0.6509732843382429 0.9614610611387069 0.531126910316402 1.0330527079939884 0.8080831375006056 0.9827230583703747 1.0 13.985008734747424 -7.3055545312858365 24.999969417842394 0.939971639720831 0.7696370196530197 0.33266901857816367 0.13123751303020095 608.8588844016259 345036.83679249714 0.05328050054586107 0.035921898816150225 4.9481797622659304e-08 7.3055545312858365 -0.1703346200678113 VAEDFVS(ph)PEHVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VAEDFVSPEHVK 12 0 Q7LBC6;Q7LBC6-2;Q7LBC6-3;Q9Y4C1 Q7LBC6;Q9Y4C1 KDM3B;KDM3A Lysine-specific demethylase 3B;Lysine-specific demethylase 3A 1 VAEDFVS(1)PEHVK 68.355 0.034710000000000005 12285000.0 27903.0 40140.0 36218.0 39334.0 39210.0 28749.0 36986.0 31525.0 24631.0 27816.0 True False 32626.4267906291 44124.833923981634 37081.57447752986 37130.243502548576 31527.081971340143 27241.351830277956 33482.418324548744 30697.502153498524 24991.181777726088 32858.820608665155 0.9929275058041866 1.3428611589408517 1.1285120339270829 1.1299931894925348 0.9594708935787604 0.8290422883618098 1.0189780918588156 0.9342241013179678 0.7605623487026706 1.0 15.003993078566426 -6.26143311259997 2.799328606648106 0.9092991747516981 1.169168341750554 0.5365294120660005 0.10611780284860814 0.2027645632611001 3.185271832259502 0.03335133319347306 0.041870171032893574 5.477304525857683e-07 6.26143311259997 0.259869166998856 VAEIEHAEK ddPTM_PC-9_AZD4547_30min_R2 2 VAEIEHAEK 9 0 P78371;P78371-2;F5GWF6;F8VQ14 P78371 CCT2 T-complex protein 1 subunit beta 0 ; 98.04799999999999 0.0038501999999999994 5075600.0 71326.0 72245.0 88254.0 91506.0 90616.0 96144.0 91215.0 96561.0 82708.0 85319.0 False True 94006.18432703658 95596.7834220245 87083.69429586074 70410.70545360698 78035.53254601611 90132.10048127019 99332.95829313081 81639.71620103708 87079.77602827156 82332.00777908255 1.1417939008517657 1.1611132292380708 1.0577137208839624 0.8552045231611086 0.9478152501200389 1.0947394933343209 1.2064926019983149 0.991591464890507 1.0576661298231482 1.0 16.32916578816603 -5.3476216177508915 4.841266903525822 1.0246257909976906 1.1511259242182148 0.2528009003648143 0.08715547904935651 0.3217506636271913 12.854372326219462 0.0257159489149248 0.05634046085921406 4.491365330101257e-06 5.3476216177508915 0.12650013322052422 VAEIEHAEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VAEIEHAEK 9 0 P78371;P78371-2;F5GWF6;F8VQ14 P78371 CCT2 T-complex protein 1 subunit beta 0 ;; 105.98 0.0021824 8570600.0 161982.0 161651.0 160597.0 178522.0 186661.0 149501.0 179653.0 150262.0 151341.0 128360.0 False True 189402.35330966872 177698.64296575857 164426.2415475142 168519.9911161333 150086.1170072001 141660.90437853074 162634.9672649156 146317.781715749 153554.07581595756 151630.65190279894 1.2491033371740885 1.171917687722336 1.0843865635618166 1.111384729943396 0.9898138346289711 0.9342497878947379 1.0725731586854277 0.9649617665005115 1.0126849280737222 1.0 17.210201896007966 -5.135723807372598 0.7599306410127795 0.9931775523915316 1.3254653657542144 0.8078379820258734 0.04095375797744013 0.7651329143910867 0.4712251897138956 0.017569387970108482 0.19859878965102118 7.316042044038008e-06 5.135723807372598 0.33228781336268276 VAEIEHAEK ddPTM_PC-9_Lapatinib_30min_R1 2 VAEIEHAEK 9 0 P78371;P78371-2;F5GWF6;F8VQ14 P78371 CCT2 T-complex protein 1 subunit beta 0 ; 130.41 0.0010630999999999998 12066100.0 191850.0 201430.0 186973.0 178906.0 202484.0 180105.0 202457.0 171770.0 189297.0 190445.0 False True 189114.18381901897 200963.60121082212 171600.80167665202 192063.3440529201 190574.28921886082 172402.32899526082 212939.23283029115 179751.06127721447 167976.37847421918 223363.1644979886 0.8466668362442634 0.8997168430277671 0.7682591803457248 0.8598702677076804 0.8532037484657725 0.7718476293203363 0.9533319126673131 0.8047480061504642 0.752032587162472 1.0 17.769031760626092 -11.804180295992019 2.3415791957099694 1.7453316709521334 0.8364708423217667 0.4093504585733163 0.05962650359004606 3649695.7889557094 1020473.5787732415 14219201.193159025 0.01467942587261378 1.5697110084455691e-12 11.804180295992019 -0.9088608286303667 VAFISLS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 2 VAFISLSPVR 10 0 Q6ZU65-2;Q6ZU65 Q6ZU65-2 UBN2 Ubinuclein-2 1 VAFIS(0.002)LS(0.998)PVR;VAFISLS(1)PVR 149.94 0.00012641 13825000.0 26012.0 23109.0 47591.0 65350.0 55833.0 48961.0 39803.0 55952.0 41645.0 45017.0 True False 34283.274916788694 30578.53232887482 46959.912244593026 50284.56714743531 48081.55169773247 45899.46093009936 43345.389891371866 47305.90404905102 43846.269680047466 43440.968532108374 0.7891922320159371 0.703910003900429 1.0810051854595208 1.157537892145951 1.1068250391837862 1.0565938670583241 0.9977998041027593 1.0889698284255789 1.0093299289043136 1.0 15.406768648458137 -5.264644481841816 24.99842537216037 1.0679254029627236 0.746551101408797 0.8555246090023256 0.05185302357642623 86.63181676007433 675696.5656039513 0.014022969223350792 0.031291882218898164 5.43695224159177e-06 5.264644481841816 -0.32137430155392666 VAFISLS(ph)PVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VAFISLSPVR 10 0 Q6ZU65-2;Q6ZU65 Q6ZU65-2 UBN2 Ubinuclein-2 1 VAFIS(0.002)LS(0.998)PVR;VAFISLS(1)PVR 123.62 0.00044006 9235800.0 30348.0 37472.0 40511.0 41903.0 45275.0 38265.0 34816.0 37990.0 31966.0 25803.0 True False 35485.31699967786 41191.972516179405 41476.935878823024 39555.31076135897 36403.68875930694 36258.31603831736 31517.976433988242 36992.802753732234 32433.442276269405 30480.879643564396 1.1641828390333242 1.3514036667533151 1.3607525886340452 1.2977089645675797 1.194312276581331 1.1895429679954392 1.0340245033132702 1.2136396057566776 1.064058605116971 1.0 14.895616917521634 -6.688918212854066 1.4823479604532737 1.095076452653883 1.302909259751663 0.6036432216247767 0.07561387848427645 0.27887695430373605 1.2747705733393082 0.03257367860866777 0.03136775537230357 2.0468300632822262e-07 6.688918212854066 0.20783280709777996 VAFISLS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 2 VAFISLSPVR 10 0 Q6ZU65-2;Q6ZU65 Q6ZU65-2 UBN2 Ubinuclein-2 1 VAFIS(0.006)LS(0.994)PVR;VAFIS(0.004)LS(0.996)PVR 111.27 0.0016202999999999999 8482300.0 33869.0 36896.0 46963.0 42936.0 39707.0 37782.0 31024.0 32514.0 43529.0 33012.0 True False 33386.02184918607 36810.56957888347 43101.88342242247 46093.65667029723 37371.51232696562 36166.151934143694 32630.270918402162 34024.719138192675 38626.30563930907 38718.080214274974 0.8622850529886803 0.9507333363422233 1.1132236718320354 1.1904943740806382 0.9652212124191816 0.9340894934354104 0.8427657243804072 0.8787811521101219 0.9976296713458414 1.0 15.24071979977536 -6.514142064938153 23.268983427602812 0.9211474794955723 1.0356176083779989 0.19391662459954795 0.09350528042589545 263.652963952041 702209.0321993406 0.03269183159727327 0.034374484554035155 3.06096197840115e-07 6.514142064938153 0.11447012888242658 VAFISLS(ph)PVRR ddPTM_PC-9_AZD4547_30min_R2 1 VAFISLSPVRR 11 1 Q6ZU65-2;Q6ZU65 Q6ZU65-2 UBN2 Ubinuclein-2 1 VAFIS(0.018)LS(0.982)PVRR 89.189 0.0043176 2762000.0 9152.7 8476.8 11484.0 15593.0 13497.0 14304.0 11948.0 12944.0 12632.0 13252.0 True False 12063.068212013368 11216.759827141208 11331.714656487695 11998.27475944848 11623.174525178563 13409.568618781093 13011.348853657044 10943.802223529392 13299.701731260888 12788.051513594872 0.9433077587456713 0.8771281391239911 0.8861173763994493 0.9382410406067894 0.908908954020248 1.048601392051439 1.0174614044856471 0.8557834015522323 1.0400100216301198 1.0 13.64250884034278 -6.717615735836435 24.028457963533622 0.9849258283122457 0.9090329558611366 0.3637910321438267 0.05350078441241842 111.82357437149909 61312.09440306694 0.017832628391717783 0.017832483810483735 1.9159504099833776e-07 6.717615735836435 -0.0758928724511091 VAFISLS(ph)PVRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VAFISLSPVRR 11 1 Q6ZU65-2;Q6ZU65 Q6ZU65-2 UBN2 Ubinuclein-2 1 VAFIS(0.01)LS(0.99)PVRR;VAFIS(0.089)LS(0.911)PVRR 94.54700000000001 0.0030202 4983400.0 18724.7 20652.7 23289.6 25883.0 26933.0 23993.0 28611.0 22516.0 18673.2 21923.1 True False 21894.421880317263 22702.963567060677 23844.912390299847 24432.859423818194 21655.67199015822 22734.764842737448 25900.758954297962 21924.978857673996 18946.260223776328 25897.58448683589 0.8454233209064925 0.8766440583908864 0.9207388589627173 0.9434416339577061 0.8362043186369795 0.8778720213961982 1.0001225777432519 0.8466032370246257 0.7315840685221813 1.0 14.660529921037456 -7.963058487800427 24.99972419396868 0.8402253168559918 0.9001059737176434 0.040076664274095286 0.07599757288775168 354.11148937679525 239640.25472265316 0.03992162282155475 0.01917764715626893 1.088783453575811e-08 7.963058487800427 0.05988065686165167 VAFISLS(ph)PVRR ddPTM_PC-9_Lapatinib_30min_R1 1 VAFISLSPVRR 11 1 Q6ZU65-2;Q6ZU65 Q6ZU65-2 UBN2 Ubinuclein-2 1 VAFIS(0.12)LS(0.88)PVRR 62.088 0.02593 2470400.0 9969.9 14000.0 10046.0 11496.0 12584.0 10479.0 9899.4 11274.0 11440.0 9865.9 True False 9827.727397744255 13967.583860157432 9220.056658681428 12341.454189531789 11843.833861095909 10030.83759774209 10411.942493863797 11797.83119776048 10151.506731459396 11571.207669514593 0.8493259889921692 1.2070981922618425 0.7968102312235318 1.066565784835621 1.0235607379426415 0.866879057418462 0.899814677191821 1.0195851232402429 0.8773074532405525 1.0 13.498251823761146 -6.738730649631931 24.987271901972683 0.9318848760959911 0.9944753872660185 0.054834708554395206 0.1148717858150937 698.8277561818404 768944.9298430519 0.03575285087974868 0.03572817254317372 1.8250272371954705e-07 6.738730649631931 0.06259051117002734 VAFS(ph)VAR ddPTM_PC-9_Lapatinib_30min_R1 2 VAFSVAR 7 0 P39023;G5E9G0;B5MCW2;H7C422 P39023 RPL3 60S ribosomal protein L3 1 VAFS(1)VAR;VAFS(1)VAR 82.75 0.022022999999999997 4356600.0 17558.800000000003 15376.1 14310.1 10975.9 13893.3 15464.3 16687.1 16108.2 14457.8 12633.7 True False 17308.408292110445 15340.497585154766 13133.578816583427 11783.104300529052 13076.123409278747 14802.927938044002 17551.07638739261 16856.645777875234 12829.410316616579 14817.418211652921 1.1681122881784174 1.0353016541768711 0.886360810566495 0.7952197968781376 0.8824832519740342 0.9990220783808664 1.184489506653045 1.1376236762095704 0.8658330441484803 1.0 13.855006473770453 -7.003034296228309 24.78670943146755 1.0632124258210816 0.9450410380923695 0.10670904525682112 0.12284567842015513 220.09792904428926 1797964.0251526649 0.04706668511996535 0.040727391984679916 9.930376251590127e-08 7.003034296228309 -0.11817138772871205 VAFSEITS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 1 VAFSEITSPSK 11 0 Q13415 Q13415 ORC1 Origin recognition complex subunit 1 1 VAFSEIT(0.121)S(0.878)PS(0.001)K 100.55 0.0040997 2636000.0 23180.0 23538.0 27408.0 22768.0 23162.0 28942.0 29100.0 26859.0 27050.0 26868.0 True False 30550.75782604804 31146.198189322604 27044.552011930948 17519.18936209345 19946.356105222334 27132.25216476247 31689.843625830243 22708.55870841903 28479.80777633049 25927.359497982732 1.1783212181103528 1.2012869336634886 1.0430893286312144 0.6757027981756694 0.7693169104541576 1.0464718617749518 1.2222549553607978 0.8758531199517583 1.0984461328792987 1.0 14.66218766583552 -5.424227356635211 4.744817584111196 0.9512048432423772 1.1842459824469849 0.27600653488998217 0.1493259523000492 0.30743620493965307 11.152152861441772 0.04345988344088266 0.093281272093736 3.765066431427082e-06 5.424227356635211 0.23304113920460767 VAFSEITS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VAFSEITSPSK 11 0 Q13415 Q13415 ORC1 Origin recognition complex subunit 1 1 VAFS(0.001)EIT(0.073)S(0.922)PS(0.005)K 80.737 0.015835 3272100.0 19243.0 32651.0 38535.0 25600.0 32349.0 27330.0 30239.0 23679.0 24628.0 23437.0 True False 22500.459833425637 35892.375497058434 39453.8205448013 24165.714996319828 26010.44566923952 25896.766688284682 27374.54300859865 23057.45133997436 24988.137908401528 27685.942572810072 0.8127034062233078 1.2964115418020035 1.4250488471195588 0.872851445558245 0.9394820350015451 0.9353760169147172 0.9887524304656602 0.8328216126049007 0.9025568785561949 1.0 14.756866019061624 -5.7912406848994005 24.99997264250857 0.9213313070730871 1.1898905602366934 0.36821495439457086 0.1518928196433188 198.72367662802966 166706.23791750125 0.04289304435535037 0.0636302163760682 1.6171835502322204e-06 5.7912406848994005 0.2685592531636063 VAFSEITS(ph)PSKR ddPTM_PC-9_AZD4547_30min_R2 2 VAFSEITSPSKR 12 1 Q13415 Q13415 ORC1 Origin recognition complex subunit 1 1 VAFS(0.001)EIT(0.05)S(0.914)PS(0.035)KR;VAFS(0.027)EIT(0.144)S(0.824)PS(0.005)KR 110.25 0.0017849 27043000.0 71327.0 52867.0 86537.0 114887.0 102488.0 91653.0 74192.0 85990.0 64648.0 82512.0 True False 94007.50230623527 69955.223879468 85389.46283772872 88401.57713645593 88259.31027165298 85921.92342122088 80794.94427105143 72702.2213536229 68065.16129849222 79623.2799946982 1.1806534761252596 0.8785775200936968 1.0724183033330763 1.1102478715062007 1.1084611218921128 1.0791055508758505 1.0147150968464405 0.9130774486866636 0.8548399576483714 1.0 16.280902682460983 -7.6323412594651145 3.243688211147469 0.9118261496319411 1.065522988119603 0.4078599123395099 0.07965213404110089 0.2462648746153292 5.1111014151434695 0.04263655831653953 0.02237072229355267 2.3316252002446346e-08 7.6323412594651145 0.15369683848766202 VAFSEITS(ph)PSKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VAFSEITSPSKR 12 1 Q13415 Q13415 ORC1 Origin recognition complex subunit 1 1 VAFSEIT(0.04)S(0.956)PS(0.004)KR 132.56 0.00012252 8754900.0 52186.0 64061.0 67918.0 65538.0 65507.0 77434.0 75226.0 80527.0 70409.0 63049.0 True False 61020.05907951723 70420.55271560009 69537.42270044933 61866.11833706276 52671.37359593418 73373.22472523361 68100.04869092366 78413.2515754091 71438.59842425857 74479.28460439068 0.8192890063812455 0.9455052245688284 0.933647833351369 0.8306486651378987 0.707194945221441 0.9851494293341821 0.9143488562309453 1.0528196127542626 0.9591740683831319 1.0 16.184551594999128 -6.889227639499588 20.38585971380323 0.981433128345428 0.8555237874534533 0.482149104374727 0.06970591929595456 2.6102448406209233 466.8091153753648 0.02600832079028288 0.022937220082960695 1.2905426463449993e-07 6.889227639499588 -0.1259093408919747 VAFSEITS(ph)PSKR ddPTM_PC-9_Lapatinib_30min_R1 1 VAFSEITSPSKR 12 1 Q13415 Q13415 ORC1 Origin recognition complex subunit 1 1 VAFS(0.01)EIT(0.364)S(0.626)PS(0.001)KR 92.792 0.0083272 7160200.0 97119.0 72027.0 78832.0 83125.0 82915.0 80885.0 69658.0 61947.0 88210.0 74197.0 True False 95734.06525055684 71860.22590682555 72350.73726031987 89238.28979687113 78038.10271716194 77425.73710214431 73264.55040078831 64825.28376864184 78274.86090752033 87021.85258871209 1.1001152285624272 0.825772191342049 0.8314088370684117 1.0254698922422911 0.8967644378474715 0.8897275201446064 0.8419097987611874 0.7449310930557063 0.8994851129803876 1.0 16.409090109966137 -6.850122103659671 2.5082246229977114 0.852123502605809 0.9305345633440962 0.07787368709121412 0.09756661109354839 0.655331627767086 8.40382186148175 0.03782381514558049 0.03316794792569127 1.4121404597715435e-07 6.850122103659671 0.07841106073828719 VAFTGSTEVGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VAFTGSTEVGK 11 0 P00352 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ; 142.0 0.00062943 15688100.0 59571.0 54345.0 62765.0 66599.0 59964.0 50603.0 57232.0 55590.0 53689.0 58537.0 False True 69655.1937191186 59740.01244640714 64261.555637588026 62867.673946871204 48214.484655175685 47949.28959850968 51810.570636202174 54130.82140247366 54474.10005539102 69149.29472136294 1.0073160398785581 0.8639280080459172 0.9293161397600648 0.909158570599982 0.6972520088520923 0.6934169002261169 0.7492566749230466 0.7828108966345034 0.7877752083357378 1.0 16.077426916432362 -6.170626496821287 6.6797314023953716 0.768102255110919 0.9247004173222371 0.38205948557236524 0.08717561961261908 0.2392190573550438 14.914970131926067 0.02472263696068057 0.03204067441794573 6.751083867409616e-07 6.170626496821287 0.15659816221131806 VAFTGSTEVGK ddPTM_PC-9_Lapatinib_30min_R1 2 VAFTGSTEVGK 11 0 P00352 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ; 137.46 0.00042207 134929000.0 251017.0 238159.0 238887.0 247695.0 222445.0 203063.0 245642.0 170207.0 215249.0 211319.0 False True 247437.45154912036 237607.55746794492 219246.63299048663 265911.3165862977 209361.22244369684 194378.46885297302 258360.14082446293 178115.43859120263 191005.39094754372 247845.20758513216 0.9983547955597578 0.9586933706851253 0.884611145507737 1.072892710644647 0.8447257241065818 0.784273663174246 1.0424254047184633 0.7186559721152643 0.770664047970084 1.0 17.919079837098153 -6.300732651922358 24.517031102261218 0.8513794366218198 0.9704972112583815 0.23725945902332712 0.10297631739678186 624.9003824647209 389904.7197401321 0.03162247375885727 0.035857223760445374 5.003424468498059e-07 6.300732651922358 0.1191177746365617 VAGHPLAQNER ddPTM_PC-9_Lapatinib_30min_R1 1 VAGHPLAQNER 11 0 O60493-4;O60493;O60493-2 O60493-4 SNX3 Sorting nexin-3 0 68.355 0.031403 1941300.0 22854.0 19309.0 18779.0 17287.0 17135.0 22485.0 14811.0 15821.0 17913.0 14894.0 False True 22528.09776908968 19264.291196841426 17235.063109036288 18558.343647741483 16127.152988706152 21523.368965095036 15577.841109220419 16556.10141740007 15895.44930774756 17468.408054992487 1.2896480147571965 1.1028074874479288 0.9866418883036391 1.0623946721027901 0.9232182427806863 1.2321311076165087 0.891772224474013 0.947773910781087 0.9099540872703982 1.0 14.092460516950288 -1.522879034669885 0.8122494237436819 0.9871823165599434 83.97391489190207 0.48991160083595364 0.09281117416516989 464.57250460181683 1.5304513633066732 0.03282584032306297 71021.46552594358 0.029999980009684915 1.522879034669885 82.98673257534213 VAGPADAPMDS(ph)GAEEEKAGAATVK ddPTM_PC-9_AZD4547_30min_R2 2 VAGPADAPMDSGAEEEKAGAATVK 24 1 Q8TEK3-1;Q8TEK3 Q8TEK3-1 DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 1 VAGPADAPMDS(1)GAEEEKAGAATVK;VAGPADAPMDS(1)GAEEEKAGAATVK 81.226 0.00015854 17331900.0 101133.0 69983.0 87526.0 128756.0 113470.0 109139.0 97462.0 101790.0 87143.0 105210.0 True False 133291.19030292126 92603.63615784523 86365.34805152754 99073.29346037 97716.6491347717 102314.52107698172 106135.92919108827 86060.69440150307 91749.20107403949 101526.6299234317 1.3128692482301976 0.9121117900563043 0.8506669443934234 0.9758355372879812 0.9624730891635684 1.0077604383612873 1.0453999041545334 0.8476662178820221 0.9036959184327693 1.0 16.631498663123097 -4.758431928629291 24.99383019871917 0.94395722380207 1.3128697512460736 0.7551556294377336 0.06282633559736835 43.12546441460592 358336.9738728113 0.016640870432455702 0.11389507651874546 1.744086704408427e-05 4.758431928629291 0.3689125274440036 VAGPADAPMDS(ph)GAEEEKAGAATVK ddPTM_PC-9_Lapatinib_30min_R1 2 VAGPADAPMDSGAEEEKAGAATVK 24 1 Q8TEK3-1;Q8TEK3 Q8TEK3-1 DOT1L Histone-lysine N-methyltransferase, H3 lysine-79 specific 1 VAGPADAPMDS(1)GAEEEKAGAATVK;VAGPADAPMDS(1)GAEEEKAGAATVK 87.963 2.6130999999999998e-05 21200000.0 179997.0 136686.0 143683.0 152788.0 156895.0 136695.0 110997.0 112419.0 153068.0 114894.0 True False 177430.20977259256 136369.5119649629 131869.9383724191 164024.53920582696 147666.74456743832 130848.87350160867 116743.8815475079 117642.39714573658 135827.86996250245 134753.27481336799 1.316704250923265 1.0119940472974285 0.9786028469813273 1.2172211727915287 1.0958304707025144 0.9710255552811843 0.8663528341644912 0.8730206913981883 1.0079745382857876 1.0 17.03996080863609 -6.808838928653865 3.6541480909887762 0.92579392010496 1.1166817203610955 0.4519569191847457 0.09951084006301136 0.21992174556599042 6.042758023536911 0.036516503235639874 0.03306766103493508 1.5529628667787144e-07 6.808838928653865 0.1908878002561355 VAGQDGSVVQFK ddPTM_PC-9_Lapatinib_30min_R1 2 VAGQDGSVVQFK 12 0 P61956-2;P61956;A8MUA9;A8MU27;Q6EEV6;P55854;P55854-2 P61956-2 SUMO2;SUMO3;SUMO4 Small ubiquitin-related modifier 2;Small ubiquitin-related modifier 4;Small ubiquitin-related modifier 3 0 ; 160.91 0.00099182 19084600.0 96984.0 98658.0 96791.0 87170.0 93285.0 86346.0 93469.0 87708.0 85824.0 92019.0 False True 95600.99037531244 98429.56346252955 88833.21760406476 93580.77259059562 87798.15970536652 82653.182862357 98308.3674726706 91783.23387379576 76157.59735321425 107924.36154238983 0.8858147410745896 0.9120235881485296 0.8231062601113783 0.8670959109991081 0.8135156738535045 0.7658436119623744 0.9109006165772653 0.8504403691815748 0.7056571497372405 1.0 16.71966103258385 -5.261367645309524 24.698786310461404 0.8363383909142756 0.8989191670473584 0.07982745717556594 0.07521705787555939 11.896372382632034 4093928.5721147307 0.018493131619036506 0.043094432923776065 5.478130258925384e-06 5.261367645309524 0.06258077613308277 VAGS(ph)PVTPLPEQEASPAR ddPTM_PC-9_Lapatinib_30min_R1 1 VAGSPVTPLPEQEASPAR 18 0 O15047 O15047 SETD1A Histone-lysine N-methyltransferase SETD1A 1 VAGS(0.937)PVT(0.063)PLPEQEASPAR 146.81 4.7656e-12 0.0 4532.0 5102.8 8119.8 5566.1 5257.2 6447.4 7314.7 6422.2 7115.6 3656.7 True False 4467.372848932985 5090.984780115096 7452.2213873344135 5975.449561965285 4947.981832052874 6171.659731623477 7693.419374898026 6720.598857393764 6314.166197410177 4288.755722753523 1.0416477733231178 1.187054033668888 1.7376185236658435 1.393282795348589 1.153710342093372 1.4390327009953991 1.7938581426033275 1.5670276629975366 1.4722606288605018 1.0 12.06634343052403 -6.993950281038942 24.904079588817538 1.521382705146954 1.3225319183201965 0.0576482263760969 0.25566241238734816 345.36144579288634 1421694.070570896 0.09123621798976923 0.08024146934277251 1.0140274671249359e-07 6.993950281038942 -0.1988507868267575 VAGTMQALIPLESGSGMT(ph)QT(ph)SGVSTETGDVVK ddPTM_PC-9_Lapatinib_30min_R1 1 VAGTMQALIPLESGSGMTQTSGVSTETGDVVK 32 0 E7EVA0 E7EVA0 MAP4 Microtubule-associated protein 2 VAGT(0.038)MQALIPLES(0.087)GS(0.226)GMT(0.642)QT(0.469)S(0.469)GVS(0.03)T(0.03)ET(0.01)GDVVK 41.916000000000004 0.031672000000000006 0.0 14440.0 14257.0 18088.0 14271.0 16060.0 34250.0 32440.0 23002.0 28105.0 22377.0 True False 14234.082952028322 14223.988792447473 16600.874461699168 15320.536946660428 15115.38237517485 32785.20734064957 34119.584469860936 24070.756892929447 24939.51894122957 26244.834634521732 0.5423575019712717 0.5419728868757142 0.6325387335404596 0.5837543714795679 0.5759374210456062 1.249206093206806 1.3000495124088522 0.9171616902195084 0.9502639010125373 1.0 14.679745886882593 -6.750540353851409 24.999913062637933 1.0917034179973497 0.5771081420418442 0.8293848588430022 0.11517592603872248 90.99189409509115 208714.61684015288 0.04180072949449078 0.04141163505009021 1.7760682315993306e-07 6.750540353851409 -0.5145952759555055 VAHLALK ddPTM_PC-9_Lapatinib_30min_R1 1 VAHLALK 7 0 A6PVX3;Q5VWC4;P55036-2;P55036 A6PVX3 PSMD4 26S proteasome non-ATPase regulatory subunit 4 0 91.584 0.0068255 0.0 30761.0 30856.0 31612.0 27873.0 30566.0 29246.0 27103.0 27802.0 31839.0 32546.0 False True 30322.342499123493 30784.55482778699 29012.983385848835 29922.873401602246 28768.167975068136 27995.21675575581 28506.260724002506 29093.782416190956 28252.956540466395 38171.53273518098 0.794370577400911 0.8064794002734464 0.7600685984272483 0.7839054724156697 0.7536550385505953 0.7334056232422095 0.7467937146188938 0.7621853337153666 0.7401577698352919 1.0 15.220209497070918 -11.13329540395573 6.944128234703182 1.0004643665149169 0.7643987578435979 0.9081332152417787 0.02246512145182565 0.0001786829091314054 1.0024577745480511e-05 0.024065126342684377 0.005825490643973527 7.357065050372742e-12 11.13329540395573 -0.23606560867131898 VAIDAGYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VAIDAGYR 8 0 O60218 O60218 AKR1B10 Aldo-keto reductase family 1 member B10 0 92.47 0.036631 4047200.0 31167.0 33487.0 30285.0 35522.0 35447.0 32467.0 34484.0 26971.0 29027.0 31317.0 False True 36442.9575236905 36811.36805212691 31007.1092565021 33531.81750387786 28501.414808418594 30764.37336511302 31217.425877460115 26263.039828136672 29451.464961311147 36994.5241947644 0.9850905861589115 0.9950491012758204 0.8381540222887996 0.9063994802945297 0.7704225268141769 0.8315926217390547 0.8438390966487445 0.7099169512187836 0.7961033586013582 1.0 15.17502412321836 -5.311492443374967 1.1761141131846629 0.8149640123714144 1.0229732614086433 0.36904242197181436 0.07586970933275082 0.7009880557429969 1.452987937160191 0.0238696553237718 0.14297122350890265 4.880985939780138e-06 5.311492443374967 0.20800924903722895 VAIDAGYR ddPTM_PC-9_Lapatinib_30min_R1 1 VAIDAGYR 8 0 O60218 O60218 AKR1B10 Aldo-keto reductase family 1 member B10 0 113.89 0.017054 21791000.0 97594.0 102090.0 85407.0 100100.0 95436.0 88016.0 91069.0 89250.0 84678.0 86596.0 False True 96202.29166345212 101853.6168773909 78385.16614055392 107461.68792381109 89822.64211439517 84251.76085531717 95784.10721596064 93396.8808231439 75140.67194112932 101564.00321808309 0.9472085445163279 1.00285153844011 0.7717809820103442 1.058068651479444 0.8843944632777392 0.8295435211864164 0.943091097052254 0.9195864466133503 0.739835665789814 1.0 16.632029640516095 -6.46920170969876 24.99967809136163 0.8818209561488171 0.9410515465862548 0.08467515095711287 0.09393720042361797 848.2463465730997 395063.9931632596 0.02812716149420205 0.031893038291581896 3.394675689863447e-07 6.46920170969876 0.059230590437437725 VAIEHLDK ddPTM_PC-9_AZD4547_30min_R2 2 VAIEHLDK 8 0 E7ENZ3;B7ZAR1;E9PCA1;P48643-2;P48643 E7ENZ3 CCT5 T-complex protein 1 subunit epsilon 0 ; 110.41 0.0031578 20854900.0 262990.0 241895.0 292690.0 382580.0 338330.0 346200.0 294710.0 337720.0 297530.0 326850.0 False True 346615.34946817777 320082.828235457 288808.73935975163 294382.091802078 291358.71950090193 324552.0592716732 320938.6190710806 285533.1340335562 313256.8283804665 315407.08098539704 1.0989459982486114 1.014824484077694 0.9156698018873048 0.9333401484911733 0.9237545288794309 1.0289942072882619 1.017537773940908 0.9052844759904932 0.9931826115057002 1.0 18.266855523873552 -4.891734658537925 3.3763553031197513 0.9628849993459714 1.1024115965324166 0.48660585281543955 0.04221134510139126 0.2302492784086008 4.528039488213118 0.011209776450405835 0.07093697327191742 1.283114289219616e-05 4.891734658537925 0.13952659718644522 VAIEHLDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VAIEHLDK 8 0 E7ENZ3;B7ZAR1;E9PCA1;P48643-2;P48643 E7ENZ3 CCT5 T-complex protein 1 subunit epsilon 0 ;; 117.89 0.0029601 13095800.0 314748.0 328471.0 347308.0 395710.0 386460.0 343148.0 393680.0 381520.0 346491.0 290368.0 False True 368028.61984363437 361079.4300907873 355589.1398929254 373539.65160912875 310735.93722632196 325152.71480247064 356387.78040362126 371505.504253854 351557.77537842863 343009.419848177 1.0729402708722442 1.0526807988264826 1.0366745614459114 1.0890069776347981 0.9059107979129555 0.9479410651357327 1.0390028954929744 1.0830766817374577 1.0249216349044739 1.0 18.387888671189543 VAIEHLDK ddPTM_PC-9_Lapatinib_30min_R1 2 VAIEHLDK 8 0 E7ENZ3;B7ZAR1;E9PCA1;P48643-2;P48643 E7ENZ3 CCT5 T-complex protein 1 subunit epsilon 0 ; 127.68 0.0028028000000000003 16791200.0 267850.0 254100.0 261450.0 256850.0 256250.0 255300.0 225320.0 216695.0 259400.0 218070.0 False True 264030.4098823257 253511.6470618578 239954.59022618568 275739.6058264822 241177.8788068836 244381.41413336725 236985.96710077292 226763.4407839902 230183.64039690245 255763.10893998935 1.0323240555551587 0.9911970812074394 0.9381907782583575 1.0781054663015532 0.9429736751576321 0.9554990754773292 0.9265838536408229 0.8866151249248246 0.8999876540088168 1.0 17.96444866051901 -6.49591356426618 23.567110699086882 0.9287626913799385 1.0043699687260643 0.40790675845423374 0.04378392471208396 362.42207713742386 316750.747238111 0.013584114486135772 0.015349573421199577 3.1921731161545674e-07 6.49591356426618 0.07560727734612582 VAIIRT(ph)PPKSPATPK ddPTM_PC-9_AZD4547_30min_R2 1 VAIIRTPPKSPATPK 15 2 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 VAIIRT(1)PPKSPATPK 87.088 0.043745 31906000.0 42895.0 46732.0 68878.0 66516.0 63965.0 58075.0 47751.0 51380.0 52825.0 51030.0 True False 56534.717728573385 61837.20510593181 67964.63271591428 51181.763861955675 55084.563866270066 54443.56106933111 52000.74649405565 43440.401594942836 55617.22165562513 49243.455232323155 1.1480656152548834 1.2557446429011379 1.3801759522208068 1.0393617511299293 1.1186169533878045 1.1055999383567754 1.0559930502180241 0.8821558395932537 1.1294337774072007 1.0 15.587644373533669 -6.270384889867611 1.0675400534612212 1.017879279567289 1.2523897277764071 0.4659397754978343 0.09473679866683392 0.4499726629761997 1.072816880785402 0.04234689172731034 0.06376801384844473 5.365560672499555e-07 6.270384889867611 0.23451044820911804 VALGITTVLTMTT(ph)QS(ph)S(ph)GS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 VALGITTVLTMTTQSSGSR 19 0 P23416-3;O75311-2;P23416-2;P23416;O75311 P23416-3 GLRA2;GLRA3 Glycine receptor subunit alpha-2;Glycine receptor subunit alpha-3 4 VALGIT(0.135)T(0.135)VLT(0.135)MT(0.135)T(0.695)QS(0.891)S(0.891)GS(0.982)R 50.675 0.021189 1506700.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 VALS(ph)DDETK ddPTM_PC-9_AZD4547_30min_R2 2 VALSDDETK 9 0 Q15054-3;Q15054-2;Q15054;H0YD46 Q15054-3 POLD3 DNA polymerase delta subunit 3 1 VALS(1)DDETK;VALS(1)DDETK 115.29 0.0019879999999999997 8013700.0 47257.0 55605.0 42829.0 52852.0 49807.0 53975.0 59325.0 55437.0 65926.0 48749.0 True False 62283.74299333707 73578.22883495987 42261.059476028524 40667.787955260166 42892.15778140094 50599.93471747128 64604.81007224673 46870.48546552838 69410.71376940358 47042.31234804081 1.3239940786186934 1.5640861420797953 0.8983627157475091 0.8644938125996239 0.9117782617500794 1.0756260096890973 1.3733340656018442 0.9963473971848752 1.4754953637455357 1.0 15.521671356625506 -5.256428312479768 24.98516145636246 1.0717104428597437 1.444040123277826 0.35778054212983135 0.19805176391050888 451.78240834681145 2252566.2379161264 0.0526781394928987 0.13051028304875195 5.540789963351291e-06 5.256428312479768 0.37232968041808223 VALS(ph)DDETK ddPTM_PC-9_Lapatinib_30min_R1 1 VALSDDETK 9 0 Q15054-3;Q15054-2;Q15054;H0YD46 Q15054-3 POLD3 DNA polymerase delta subunit 3 1 VALS(0.841)DDET(0.159)K 107.03 0.0029177 0.0 27470.0 30510.0 23911.0 23154.0 29024.0 31332.0 28024.0 32213.0 24095.0 23598.0 True False 27078.272762618948 30439.355969528795 21945.129879129174 24856.82239947975 27316.865383379496 29992.003398459343 29474.945597514892 33709.73357933813 21381.167368401588 27676.88285764151 0.97837147708788 1.0998115693192874 0.792904677597036 0.8981077286532957 0.9869921234947665 1.0836481677769083 1.0649662300889113 1.2179743561703504 0.7725280147470909 1.0 14.75639384640206 -6.540544425971836 6.471562061518579 1.04327934355598 0.9426734646957802 0.08689647431648617 0.12577482836974457 0.35184865228653717 58.54204729196617 0.04110581817313524 0.042087515691484174 2.8804183835137365e-07 6.540544425971836 -0.10060587886019978 VALS(ph)DDETKETENMR ddPTM_PC-9_AZD4547_30min_R2 1 VALSDDETKETENMR 15 1 Q15054-3;Q15054-2;Q15054;H0YD46 Q15054-3 POLD3 DNA polymerase delta subunit 3 1 VALS(1)DDETKETENMR 144.88 0.00052309 7813700.0 11829.0 11144.0 12107.0 15483.0 16124.0 11962.0 12241.0 15672.0 11493.0 14378.0 True False 15590.375941515198 14746.080067202442 11946.453269426731 11913.633559965427 13885.460920499312 11214.014249011421 13330.425286040821 13250.25250673306 12100.496516575466 13874.630596322593 1.1236606144777184 1.0628088412754442 0.8610285647960302 0.8586631173534148 1.000780584686672 0.8082387614689824 0.9607769513931411 0.9549985792230734 0.8721310763965598 1.0 13.760161740637564 -5.120858081513411 4.42797376666561 0.9123072512132746 1.1107016229496225 0.5782684455391283 0.061786323414564547 0.14181424677432602 4.3655593499667225 0.015276388126219488 0.045749519659643516 7.570802528274977e-06 5.120858081513411 0.19839437173634789 VALS(ph)DDETKETENMR ddPTM_PC-9_Lapatinib_30min_R1 3 VALSDDETKETENMR 15 1 Q15054-3;Q15054-2;Q15054;H0YD46 Q15054-3 POLD3 DNA polymerase delta subunit 3 1 VALS(1)DDETKETENMR;VALS(0.999)DDET(0.001)KETENMR;VALS(1)DDETKETENMR 190.18 7.868600000000001e-07 37779000.0 68775.8 71875.0 69387.0 72787.0 67337.0 62652.0 71264.7 66632.0 59284.8 52313.6 True False 67795.04448006282 71708.57785348674 63682.26870156566 78139.99879031425 63376.370049635596 59972.5200089453 74954.43746514485 69727.96597207515 52607.521527379686 61355.936056509665 1.1049467881579158 1.1687308916197148 1.037915363933384 1.2735523864935616 1.0329297232343597 0.9774526127954397 1.221633020089707 1.1364502027620398 0.8574153522639999 1.0 15.90491530787129 -8.251219381886054 24.756981586498238 0.9287076747604234 1.1191015718889803 0.41578966493481406 0.09032085569163523 510.8153789766477 1237410.250360089 0.06167934393549788 0.022730950843057544 5.6076463676405185e-09 8.251219381886054 0.19039389712855692 VALS(ph)SETEVALAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VALSSETEVALAR 13 0 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 VALS(0.496)S(0.496)ET(0.008)EVALAR 133.15 4.7452e-05 2309000.0 18871.0 18884.0 19618.0 21289.0 31056.0 21597.0 24064.0 22212.0 21365.0 16185.0 True False 22065.48758076054 20758.67871999177 20085.7675216793 20096.24634986923 24970.799737361365 20464.415300654397 21784.483711727175 21628.95853555936 21677.422706391044 19119.2123796105 1.1541002392071373 1.0857496798419197 1.0505541296826417 1.0511022081276047 1.30605797150887 1.0703586996333843 1.1394027786918162 1.131268281669665 1.1338031230569268 1.0 14.222735471935334 -4.726913941636866 22.41748674507846 1.1141760951562436 1.154101286218764 0.02451892411029455 0.07869096547377653 7350.246626656111 4771533.300319583 0.019340768038254873 2.790179472707563 1.8753660876135783e-05 4.726913941636866 0.03992519106252046 VALS(ph)SETEVALAR ddPTM_PC-9_Lapatinib_30min_R1 1 VALSSETEVALAR 13 0 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 VALS(0.43)S(0.43)ET(0.14)EVALAR 68.46300000000001 0.032764 1610300.0 17397.0 14094.0 17263.0 12569.0 17216.0 18209.0 16191.0 14640.0 15619.0 13071.0 True False 17148.91558978092 14061.36620893278 15843.702777107068 13493.366188954864 16203.388727958278 17430.24351725219 17029.290756828566 15320.227845947606 13859.823744638485 15330.304933987287 1.1186284724031663 0.9172267785592921 1.0334890822674752 0.8801759813035467 1.0569514955984576 1.1369795703547514 1.1108253117049633 0.9993426687803619 0.9040801082769889 1.0 13.904098773374317 -4.71224099989567 22.973637641412946 1.0104680579184346 1.1186332660770069 0.14750104617173843 0.08123369707375293 12730.669736837855 5943338.69824908 0.021563494253176604 15.7611896614745 1.939809134613027e-05 4.71224099989567 0.10816520815857222 VALSDDET(ph)KETENMR ddPTM_PC-9_Lapatinib_30min_R1 1 VALSDDETKETENMR 15 1 Q15054-3;Q15054-2;Q15054;H0YD46 Q15054-3 POLD3 DNA polymerase delta subunit 3 1 VALS(0.012)DDET(0.987)KETENMR 113.43 0.0047612999999999996 21452000.0 98507.0 109590.0 81806.0 106950.0 108760.0 103960.0 92687.0 87646.0 93845.0 85214.0 True False 97102.27211602886 109336.25108818954 75080.22646029181 114815.45977474147 102362.950630387 99513.87314259636 97485.87933902584 91718.35312745396 83275.18786833977 99943.12635948224 0.9715752913988782 1.0939846998073832 0.7512295161774122 1.1488079666606126 1.0242120129622618 0.9957050251225691 0.9754135465843042 0.9177054637810222 0.8332257645094061 1.0 16.608819727829122 -7.7064033043264715 3.2257718132334343 0.9043276029174033 0.9980043954446717 0.10445517424604689 0.10416722186397187 0.5179366708213878 10.865946080611852 0.057203483218325565 0.028348337737108775 1.9660596750711626e-08 7.7064033043264715 0.09367679252726835 VALSS(ph)ETEVALAR ddPTM_PC-9_AZD4547_30min_R2 1 VALSSETEVALAR 13 0 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 VALS(0.304)S(0.489)ET(0.207)EVALAR 140.01 7.0913e-05 2431800.0 14486.0 16574.0 16678.0 26242.0 22165.0 17970.0 14893.0 19972.0 16859.0 22268.0 True False 19092.246672481968 21931.221377764992 16456.838822788395 20192.312334858412 19087.77234574965 16846.333059248886 16218.448148436079 16885.78631090305 17750.132321669356 21488.404097851697 0.8884906755076667 1.0206072669657942 0.7658474192801348 0.9396841311671507 0.8882824549850098 0.7839732063179646 0.7547534974948427 0.7858092315283296 0.8260330660592857 1.0 14.391270720127599 -6.667720777445404 5.950859079305644 0.812281450831329 0.9033118128738964 0.12804709841859863 0.08631797171177708 0.33954645353617946 17.675147395995676 0.02768074259442652 0.02754298119710402 2.1492118307194756e-07 6.667720777445404 0.09103036204256743 VALSS(ph)ETEVALAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VALSSETEVALAR 13 0 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 VALS(0.003)S(0.98)ET(0.017)EVALAR 189.99 1.9442e-05 2260300.0 14594.0 12632.0 13967.0 12035.0 16040.0 13834.0 18431.0 13441.0 12317.0 10977.0 True False 17064.475955361104 13886.021478020339 14300.026250142471 11360.71796799645 12897.07714410344 13108.520686634844 16685.082251115513 13088.187991916693 12497.112823525327 12967.043206115814 1.3159882082688492 1.0708703022961392 1.1027977637490993 0.8761224735210451 0.9946043164274045 1.0109105428485272 1.2867299033326358 1.0093425142397723 0.9637596347046298 1.0 13.662561927899041 -4.552830601710031 1.9038576142252008 1.0324761507678708 1.5666893375407485 0.4144129121316732 0.10114883861173282 1.8993047516794834 4.265283200656557 0.028728845935893522 2.211645913668745 2.8000732863795057e-05 4.552830601710031 0.5342131867728777 VALSS(ph)ETEVALAR ddPTM_PC-9_Lapatinib_30min_R1 1 VALSSETEVALAR 13 0 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 VALS(0.05)S(0.936)ET(0.014)EVALAR 139.19 6.7352e-05 1947500.0 20418.0 16050.0 17771.0 17197.0 19094.0 17085.0 19091.0 20094.0 17320.0 14441.0 True False 20126.835575797388 16012.837211109061 16309.936978043766 18461.724747510292 17970.92846024835 16354.31437708023 20079.438567019584 21027.64059675351 15369.239212314402 16937.10760857703 1.188327785412727 0.9454292657974309 0.9629706178275882 1.0900163814370045 1.0610388075439627 0.9655907463679531 1.1855293732001362 1.2415130778353807 0.9074299796342646 1.0 14.047899902682081 -7.253723093383855 24.76253428645317 1.1037441982558758 1.0317989085914119 0.030912018950064235 0.10968013598806273 1371.6950307679424 4401947.690569894 0.041789367830008084 0.03172899743688804 5.575411244303916e-08 7.253723093383855 -0.0719452896644639 VANPSGNLTETYVQDR ddPTM_PC-9_AZD4547_30min_R2 2 VANPSGNLTETYVQDR 16 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 178.67 6.792899999999999e-29 0.0 11610.2 13040.599999999999 19294.6 20196.8 15846.2 16273.400000000001 16777.4 21858.8 12913.599999999999 17318.8 False True 15302.002092837927 17255.718927167993 19038.740997132314 15540.739797449449 13646.228655322258 15255.821725452473 18270.556097869558 18481.024725253727 13596.186532363088 16712.474083432448 0.9156036393203588 1.0325053514532645 1.139193449281454 0.9298886400581124 0.8165295328026958 0.9128404118559564 1.0932286869471757 1.1058221920340623 0.8135352350877466 1.0 14.028637702636516 VANPSGNLTETYVQDR ddPTM_PC-9_Lapatinib_30min_R1 2 VANPSGNLTETYVQDR 16 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 249.3 1.2922999999999998e-46 29094000.0 24402.1 24394.7 24163.0 26074.1 22966.5 22792.8 21474.0 18834.6 23975.1 23837.5 False True 24054.121579202925 24338.215570955887 22176.41141187731 27991.676294647765 21615.655623876282 21818.00507661189 22585.818646911026 19709.724275087774 21274.77176900455 27957.780113527806 0.8603730869019878 0.8705346229967472 0.7932107385431116 1.001212406027314 0.7731535027495696 0.7803911822761247 0.807854506158825 0.7049817329935619 0.7609606943975649 1.0 14.770962192825474 VANSPT(ph)MVNLLLGK ddPTM_PC-9_Lapatinib_30min_R1 1 VANSPTMVNLLLGK 14 0 Q6UB99;A0A087WTN8;A0A2R8Y438 Q6UB99 ANKRD11 Ankyrin repeat domain-containing protein 11 1 VANS(0.122)PT(0.878)MVNLLLGK 85.958 0.016357 631380.0 3014.4 2209.5 2896.0 2658.0 2652.5 2759.3 2227.7 3520.8 2367.4 1208.4 True False 2971.4141032267416 2204.384038501277 2657.90205888328 2853.47818682807 2496.485165015646 2641.291171242463 2343.0394057801846 3684.389221312318 2100.7584821728124 1417.270329908212 2.096575396042604 1.555373023750551 1.8753670367567887 2.0133619723859404 1.7614742313679341 1.8636466985190632 1.6532057126546416 2.5996375875242754 1.4822567281916257 1.0 10.468899248578571 -8.525039968227667 24.983086008452307 0.9999999654894973 1.9081327564048824 0.5398580031147964 0.27179979748068195 157.88400105386702 1825098.5869006945 0.25088934871561036 0.0647793512488844 2.98510788606553e-09 8.525039968227667 0.9081327909153851 VAPEEHPVLLT(ph)EAPLNPK ddPTM_PC-9_AZD4547_30min_R2 2 VAPEEHPVLLTEAPLNPK 18 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 VAPEEHPVLLT(1)EAPLNPK;VAPEEHPVLLT(1)EAPLNPK 169.51 1.7458e-07 22806000.0 88322.0 91987.0 116836.0 140675.0 116660.0 111002.0 92482.0 117936.0 99999.0 102698.0 True False 116406.55878827533 121719.9988461729 115286.67830071364 108244.55215708446 100463.77269817973 104061.02739247314 100712.71883862642 99711.70109967273 105284.74298799528 99102.57427883845 1.1746068115319566 1.2282223719405843 1.1633065956121285 1.0922476327660653 1.0137352478403978 1.0500335450387335 1.0162472526218906 1.0061464278326455 1.0623815148510922 1.0 16.596634912754126 -5.854630315333647 2.008481117572058 1.0254127685458205 1.2020306832118528 0.9140372450949631 0.02262039052637115 0.07904190339775123 0.6504822481883645 0.006677811950844234 0.012038965859259513 1.3975574983001363e-06 5.854630315333647 0.17661791466603227 VAPEEHPVLLT(ph)EAPLNPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VAPEEHPVLLTEAPLNPK 18 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 VAPEEHPVLLT(1)EAPLNPK;VAPEEHPVLLT(1)EAPLNPK;VAPEEHPVLLT(1)EAPLNPK 156.67 2.8139e-05 17555800.0 160334.0 174272.3 171381.0 202621.0 210871.0 216206.0 187719.0 222030.0 170531.5 138127.6 True False 187475.37945915185 191572.90221849256 175467.3730060616 191268.8022761454 169552.34130013967 204867.7767510894 169936.89735213222 216201.9477602309 173025.20057359774 163169.0404625202 1.148964159669829 1.1740762933670417 1.0753717280476764 1.1722125823255036 1.0391207843076438 1.2555554421988977 1.0414775797567222 1.325018196757076 1.060404596871681 1.0 17.316007822136626 -8.5157579275598 24.85925602939482 0.9999999668162076 1.1512071102878842 0.26621166572498267 0.08510173201081242 514.5804932052828 1796432.408995375 0.0750369931563885 0.019374468380962396 3.049594336665071e-09 8.5157579275598 0.15120714347167663 VAPEEHPVLLT(ph)EAPLNPK ddPTM_PC-9_Lapatinib_30min_R1 2 VAPEEHPVLLTEAPLNPK 18 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 1 VAPEEHPVLLT(1)EAPLNPK;VAPEEHPVLLT(1)EAPLNPK 131.31 8.560299999999999e-05 20736900.0 75076.0 76666.0 78270.0 70156.0 70323.0 70824.0 69479.0 66653.0 72285.0 56302.0 True False 74005.40247274793 76488.48458734502 71834.94273093728 75315.50627355542 66186.73940033746 67795.02261880769 73076.28265664206 69749.94170873953 64143.50210520476 66033.72568230062 1.1207212936734843 1.15832453488001 1.0878523358888956 1.140561213158122 1.0023172055863245 1.0266726876048304 1.106650910600204 1.056277545875849 0.9713748761323866 1.0 16.010915425950543 -5.317935191563444 0.2782878188782215 0.9947417300803979 1.2353732910409378 0.5418150225610255 0.041837638601740605 5.330649536431765 0.43703623385052787 0.057477042719414784 0.429858875328047 4.809111079883834e-06 5.317935191563444 0.24063156096053995 VAPEEHPVLLTEAPLNPK ddPTM_PC-9_AZD4547_30min_R2 5 VAPEEHPVLLTEAPLNPK 18 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ;;;; 188.9 6.2017e-11 309212600.0 308266.0 301522.0 373151.0 493995.0 446469.0 393663.0 350002.0 438774.0 346557.0 381680.0 False True 406288.17566887575 398983.08991592017 368202.7739274682 380112.08489666914 384484.4859659146 369047.1903785804 381151.49995628337 370971.56032346183 364875.2955098618 368317.49937434954 1.1030922406864347 1.0832585760754279 0.9996885148083482 1.032022875758971 1.0438941582168306 1.0019811467157287 1.0348449384124692 1.0072059051052982 0.9906542483853334 1.0 18.49059041813343 -5.163028154938748 4.574199909749031 1.0161630180510375 1.0980959562731125 0.7759495095739023 0.017112352521697346 0.10047125007457357 3.463000290618691 0.004473122474561778 0.012952599630093183 6.870238994003762e-06 5.163028154938748 0.08193293822207504 VAPEEHPVLLTEAPLNPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 VAPEEHPVLLTEAPLNPK 18 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ;;;;; 239.87 9.091899999999998e-44 386185300.0 417782.0 396883.0 417344.0 480366.0 519326.0 427790.0 478964.0 443932.0 398659.0 377185.0 False True 488504.24102937407 436282.921331629 427295.0637459346 453452.6503875849 417567.79831288353 405355.9393187452 433593.06252093037 432279.25538483536 404488.63368626864 445565.6547051834 1.0963687076657687 0.9791664072947981 0.958994615571665 1.0177010853487352 0.9371633426036279 0.9097558015034986 0.973129454530837 0.970180827045255 0.9078092743793412 1.0 18.76527850492407 VAPEEHPVLLTEAPLNPK ddPTM_PC-9_Lapatinib_30min_R1 5 VAPEEHPVLLTEAPLNPK 18 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ;;;; 215.48 1.546e-27 961103000.0 608908.0 596042.0 654658.0 567256.0 617748.0 554204.0 641082.0 523783.0 591112.0 564691.0 False True 600224.8602599476 594661.901369712 600834.5462929594 608973.8985505429 581413.2771792974 530501.9868326237 674274.0891216827 548119.8703438495 524534.7418746876 662297.0869465385 0.906277367196692 0.8978778754883967 0.9071979299547478 0.9194875087827467 0.8778738252645067 0.8010030502753012 1.0180840326965095 0.827604229502061 0.791993128481069 1.0 19.337118987119048 -6.277693785087755 21.94047826520994 0.8798182979368879 0.9069712721973143 0.017201286612705036 0.07103247736029863 736.8160209063597 994560.7250767162 0.02174978108664891 0.02477409903567403 5.276017348459981e-07 6.277693785087755 0.0271529742604264 VAPGPSSGSTPGQVPGS(ph)SALSSPRR ddPTM_PC-9_AZD4547_30min_R2 1 VAPGPSSGSTPGQVPGSSALSSPRR 25 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-5 Q8NEY1-2 NAV1 Neuron navigator 1 1 VAPGPSSGSTPGQVPGS(0.336)S(0.221)ALS(0.221)S(0.221)PRR 75.225 7.7991e-05 12899000.0 5476.2 4012.1 5088.1 7021.4 6675.9 5015.0 4610.8 6742.2 4810.1 5325.1 True False 7217.517687963947 5308.9328641082975 5020.628469494522 5402.7247095486155 5749.0665194220655 4701.411257213869 5021.15226769684 5700.347910343004 5064.352065986224 5138.669869834294 1.4045497902741684 1.0331336704997345 0.97702880252481 1.051385834545319 1.1187849511740389 0.914908210938539 0.977130735168001 1.1093041691208745 0.985537540700106 1.0 12.327179254872556 -4.761847833006924 6.21291872380264 1.0194980967926945 1.4171468510028835 0.7931505628553177 0.059171290530942715 0.056124478086869774 9.097177262139981 0.0149026401088667 0.09488670062466147 1.7304225540521408e-05 4.761847833006924 0.39764875421018897 VAPGPSSGSTPGQVPGSSALS(ph)SPRR ddPTM_PC-9_AZD4547_30min_R2 1 VAPGPSSGSTPGQVPGSSALSSPRR 25 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-5 Q8NEY1-2 NAV1 Neuron navigator 1 1 VAPGPSSGSTPGQVPGS(0.008)S(0.019)ALS(0.654)S(0.319)PRR 82.94200000000001 1.3525e-05 13567000.0 9851.9 10992.0 11067.0 18307.0 16699.0 15260.0 13458.0 14114.0 14864.0 15364.0 True False 12984.599267749905 14544.949039724439 10920.244348950664 14086.6039903305 14380.632095721789 14305.789787653759 14655.735928399423 11933.005607454721 15649.680694542578 14826.11103643765 0.8757926630819154 0.9810360251570889 0.7365548741751856 0.950121306640043 0.9699530821251088 0.9649050754101927 0.9885084424621197 0.8048641736276871 1.0555485963973201 1.0 13.855852600792831 -5.954473188817414 24.999920594513043 0.9558955206265831 0.87065517048491 0.22866555641860087 0.08137690986518964 209.1303660627961 114837.3440677298 0.022096902031533333 0.032774990597212214 1.1105210912696273e-06 5.954473188817414 -0.08524035014167308 VAPGPSSGSTPGQVPGSSALS(ph)SPRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VAPGPSSGSTPGQVPGSSALSSPRR 25 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-5 Q8NEY1-2 NAV1 Neuron navigator 1 1 VAPGPSSGSTPGQVPGS(0.026)S(0.315)ALS(0.56)S(0.099)PRR 94.57 1.2931e-06 6910000.0 4251.5 4849.4 5118.5 4072.0 6222.7 6368.6 5643.3 5122.0 5582.4 1933.0 True False 4971.194979047397 5330.816383431903 5240.544452019344 3843.859041602121 5003.406605025715 6034.619404720452 5108.725770046123 4987.552927207594 5664.032039136783 2283.4375983804184 2.177066271735796 2.3345575054089105 2.295024158197414 1.683365047649416 2.19117290902738 2.6427783307941706 2.2372959846459595 2.18423000950196 2.4804847056710155 1.0 11.156991649050033 -10.765652430193988 7.547450959202799 0.9999976057054204 2.2425396680329786 0.7175650375165983 0.2347466315704219 9.898995739922218e-06 9.933989411956868e-07 0.2378990311254936 0.057698879398587116 1.7153295520966023e-11 10.765652430193988 1.242542062327558 VAPGPSSGSTPGQVPGSSALS(ph)SPRR ddPTM_PC-9_Lapatinib_30min_R1 1 VAPGPSSGSTPGQVPGSSALSSPRR 25 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-5 Q8NEY1-2 NAV1 Neuron navigator 1 1 VAPGPSSGSTPGQVPGS(0.014)S(0.168)ALS(0.497)S(0.32)PRR 90.59200000000001 2.6432999999999997e-06 9812300.0 8628.6 3517.8 7656.0 7374.3 6402.6 5956.5 4157.9 4453.8 5648.0 4492.6 True False 8505.554581708557 3509.654750232988 7026.553233014635 7916.630621943656 6026.011655995917 5701.754380279683 4373.175717239052 4660.739807396275 5011.862763923309 5269.139923986785 1.6142206706237943 0.6660773486496219 1.3335294439662821 1.5024521527516586 1.1436423672416847 1.082103429123888 0.8299600656515076 0.8845352134565869 0.9511728358375398 1.0 12.363351776190042 -6.915136386534105 2.529318651200547 0.9091550902671792 1.2418396611319298 0.304200343775607 0.2392895510089138 0.38175436172424876 4.956969841538847 0.09544942498703794 0.08045972280795523 1.2158041276135924e-07 6.915136386534105 0.33268457086475056 VAPGPSSGSTPGQVPGSSALSS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 VAPGPSSGSTPGQVPGSSALSSPR 24 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-5 Q8NEY1-2 NAV1 Neuron navigator 1 1 VAPGPSSGSTPGQVPGSS(0.003)ALS(0.358)S(0.639)PR 166.98 5.5163e-10 5764100.0 6760.9 11461.0 10387.0 8457.6 14182.0 11330.0 10985.0 9658.5 9635.1 9178.7 True False 6664.488326202785 11434.462758661737 9533.0209549795 9079.600117726517 13347.842642884789 10845.44231151999 11553.749549982203 10107.269170087777 8549.893575898985 10765.226065151026 0.6190755573426305 1.0621665248328738 0.885538389745442 0.843419363678652 1.2399036083500519 1.0074514223745508 1.0732472760032201 0.9388812746633186 0.7942140298917204 1.0 13.394090995352585 -4.754011056981262 24.997346604216904 0.9850908479227986 0.6190749102777187 0.44581303530289285 0.12162025427282303 258.534215345486 869931.2331092106 0.031056077438330495 0.3157752076953772 1.7619311877064452e-05 4.754011056981262 -0.3660159376450799 VAPGPSSGSTPGQVPGSSALSS(ph)PRR ddPTM_PC-9_Lapatinib_30min_R1 1 VAPGPSSGSTPGQVPGSSALSSPRR 25 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-5 Q8NEY1-2 NAV1 Neuron navigator 1 1 VAPGPSSGSTPGQVPGS(0.029)S(0.082)ALS(0.231)S(0.657)PRR 110.1 1.3462e-07 7131300.0 14853.0 12923.0 13842.0 12317.0 17220.0 10880.0 12740.0 11773.0 15778.0 9585.3 True False 14641.193496293392 12893.077587486752 12703.964191665178 13222.833268307511 16207.1534558226 10414.687762518757 13399.614862701255 12320.016559449534 14000.915490294254 11242.106333390584 1.3023532300888363 1.146856043265892 1.1300341604075277 1.1761882405465156 1.4416474079848498 0.9264000404964787 1.191913193607018 1.0958815184710902 1.2453996675613743 1.0 13.456624745361236 -6.773165437877889 24.99997353924865 1.1041612032730808 1.2246842426680529 0.27202736790989857 0.11859139598844383 375.7813107604402 801161.7710288923 0.041280424875442805 0.036692357387957286 1.6859106810171824e-07 6.773165437877889 0.12052303939497211 VAPLWHSSS(ph)EVISMADR ddPTM_PC-9_Lapatinib_30min_R1 1 VAPLWHSSSEVISMADR 17 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 VAPLWHS(0.009)S(0.377)S(0.614)EVISMADR 82.709 0.0029676999999999998 10177000.0 42107.0 29477.0 42790.0 28876.0 38028.0 42385.0 28383.0 35311.0 41287.0 27639.0 True False 41506.5464585219 29408.747817561467 39271.97137417662 30999.637367512183 35791.26780592457 40572.29235426076 29852.53286091441 36951.67796914317 36636.82328861571 32416.36432334746 1.280419545032919 0.9072191910300133 1.2114859946182026 0.9562959330755393 1.1041111041606348 1.2515990982072933 0.9209093457594661 1.139908152578641 1.13019532120166 1.0 14.98443467315618 -10.842397173665208 3.9468935836512102 0.9998081706394581 1.0940576434278069 0.05134802970673513 0.12677380965813012 84787142.87781012 45.35975983367992 149416.1367661673 0.028261833871458943 1.4374833608079003e-11 10.842397173665208 0.09424947278834872 VAPVINNGS(ph)PTILGK ddPTM_PC-9_AZD4547_30min_R2 2 VAPVINNGSPTILGK 15 0 H0Y4T7;E7ESY4;Q13330-3;Q13330;F8W9Y9 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 VAPVINNGS(0.995)PT(0.005)ILGK;VAPVINNGS(1)PTILGK 240.5 2.0314e-32 131249000.0 57351.0 57726.0 77521.0 85461.0 80089.0 70625.0 72387.0 77038.0 63767.0 79076.0 True False 75587.42502509426 76384.80060654417 76493.02088867834 65759.28680928795 68970.0247867693 66208.80758538985 78829.30276779986 65133.54725712736 67137.59343708934 76307.57330886129 0.9905625581768644 1.0010120528583748 1.0024302644125038 0.8617661911894607 0.9038424601396685 0.867657097643561 1.0330469093641814 0.8535659624961978 0.8798287054070545 1.0 16.219538627080205 -5.741660193045667 24.817621884591112 0.9107181018148973 0.9983027267675663 0.3171057572698296 0.05615890282085156 256.5178304406409 321858.7965361775 0.014954532412864593 0.02585600429444139 1.8127579020671862e-06 5.741660193045667 0.08758462495266894 VAPVINNGS(ph)PTILGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VAPVINNGSPTILGK 15 0 H0Y4T7;E7ESY4;Q13330-3;Q13330;F8W9Y9 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 VAPVINNGS(0.722)PT(0.278)ILGK;VAPVINNGS(0.991)PT(0.009)ILGK;VAPVINNGS(0.985)PT(0.015)ILGK 167.92 0.00021643 120256000.0 94887.0 110553.0 119370.0 112439.0 130413.0 97399.0 118233.0 124238.0 93148.0 81027.0 True False 110949.4949963235 121527.97122067594 122216.23351324622 106139.4073621562 104859.50882755386 92291.2249788598 107033.11430720726 120976.88414104216 94510.11328129713 95716.55369062115 1.1591463620278146 1.269665136643798 1.276855766331479 1.1088929058731494 1.095521148478506 0.9642138315715708 1.1182299213693374 1.2639076468639736 0.9873956973709739 1.0 16.546480832600558 -5.850823949493037 5.401890450224529 1.0837174312021944 1.2381378661930427 0.418221999737295 0.08562867223046892 0.21181045364449289 9.91127390120756 0.02484685900573056 0.037694520928385315 1.4098601994229913e-06 5.850823949493037 0.15442043499084823 VAPVINNGS(ph)PTILGK ddPTM_PC-9_Lapatinib_30min_R1 2 VAPVINNGSPTILGK 15 0 H0Y4T7;E7ESY4;Q13330-3;Q13330;F8W9Y9 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 VAPVINNGS(0.99)PT(0.01)ILGK;VAPVINNGS(0.978)PT(0.022)ILGK 233.84 8.2484e-32 104209000.0 96159.0 125986.0 151348.0 114298.0 141187.0 130386.0 120769.0 118402.0 126838.0 95991.0 True False 94787.75502659923 125694.28715755708 138904.75166017463 122703.85620695054 132882.65824432197 124809.69472461134 127021.82789274475 123903.38916775206 112552.16877664746 112582.9164500323 0.8419372851179326 1.116459682525137 1.2337995500571772 1.0898976512249994 1.1803092550307073 1.1086024297479065 1.1282513537399868 1.1005523135718742 0.9997268886403518 1.0 16.780628401120786 -10.081333712755898 8.099901244307198 1.0000194213839517 1.0987200430842958 0.057506038620871 0.10099799453394845 0.0 0.0 0.09729367894666333 0.023597183587031906 8.292133534372898e-11 10.081333712755898 0.0987006217003441 VAPVINNGSPT(ph)ILGKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VAPVINNGSPTILGKR 16 1 H0Y4T7;E7ESY4;Q13330-3;Q13330;F8W9Y9 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 VAPVINNGS(0.357)PT(0.643)ILGKR 67.64399999999999 0.0209 12339000.0 24733.0 13200.0 24590.0 36447.0 37630.0 49376.0 32712.0 43200.0 38474.0 29244.0 True False 28919.808400983 14510.408764239106 25176.318858094324 34404.99275276832 30256.67162921523 46786.63563851972 29613.28254562914 42066.04577418354 39036.60946434302 34545.70570462339 0.8371462620638417 0.42003509461661165 0.7287828789303 0.9959267599551096 0.8758446531073719 1.3543401324193554 0.8572203676726707 1.217692471934469 1.129998900532479 1.0 15.076218763283295 -5.838637598567616 1.7691425112383363 1.0906512601070957 0.6121777364706119 0.5472115062643576 0.16864230174814077 0.24525092249816363 1.5663779799474569 0.05134819808431499 0.09869055196145865 1.4499813004499731e-06 5.838637598567616 -0.47847352363648377 VAQGATEKS(ph)PEDK ddPTM_PC-9_AZD4547_30min_R2 1 VAQGATEKSPEDK 13 1 P49321;P49321-3;P49321-4 P49321 NASP Nuclear autoantigenic sperm protein 1 VAQGAT(0.006)EKS(0.994)PEDK 135.55 0.00024826 4738400.0 12528.0 13444.0 9038.5 7887.1 9325.2 12203.0 14240.0 10562.0 13525.0 10729.0 True False 16511.643401411995 17789.51008825104 8918.64358434901 6068.850949480292 8030.556944668832 11439.944480913427 15507.332413464701 8929.885590614756 14239.903888165245 10353.380975653437 1.5948068983687609 1.7182319601764953 0.861423297889038 0.5861709294530492 0.7756458458887143 1.1049476985165625 1.4978037077869608 0.8625091273675612 1.3753868346631102 1.0 13.337814347302459 -5.257311608761056 24.993055157447632 1.0006692672272637 1.6565194972886614 0.5020736971892081 0.258257500941395 295.5480896063034 1789483.8007940333 0.0718914248080087 0.17624947260755036 5.529532197671343e-06 5.257311608761056 0.6558502300613978 VAQGATEKS(ph)PEDK ddPTM_PC-9_Lapatinib_30min_R1 1 VAQGATEKSPEDK 13 1 P49321;P49321-3;P49321-4 P49321 NASP Nuclear autoantigenic sperm protein 1 VAQGAT(0.02)EKS(0.98)PEDK 130.47 0.00038686 9601400.0 19412.0 27747.0 19990.0 21266.0 28968.0 28134.0 28931.0 27200.0 18280.0 27236.0 True False 19135.181320275184 27682.753526270615 18346.49936363147 22829.972581296377 27264.15919327927 26930.774403557232 30428.905619529807 28463.8112984819 16221.113903066229 31943.706310311212 0.5990282133948395 0.8666105697739529 0.5743384685987218 0.7146939168397944 0.8535064443814581 0.8430698098067649 0.9525790565419631 0.8910616389336755 0.5078031254573037 1.0 14.963244092589555 -6.211936423733423 5.236839971032335 0.841666404818775 0.6913087406037626 0.21547646180867208 0.1430406844732844 0.3512932424354859 22.48755171596831 0.042183747930563585 0.05415644435384159 6.138518602164605e-07 6.211936423733423 -0.1503576642150124 VAQLEQVYIR ddPTM_PC-9_Lapatinib_30min_R1 1 VAQLEQVYIR 10 0 P62318-2;P62318 P62318-2 SNRPD3 Small nuclear ribonucleoprotein Sm D3 0 104.42 0.01201 6573400.0 21005.0 23557.0 20770.0 15871.0 21171.0 23356.0 16963.0 21014.0 25128.0 15333.0 False True 20705.464848154763 23502.455213837773 19062.370774518557 17038.20628410396 19925.763403787467 22357.118325495212 17841.261139403556 21990.38715537863 22297.820030429342 17983.288620061754 1.1513725484590294 1.3069053002696605 1.060004717560558 0.9474466347104343 1.1080155484775311 1.243216343675545 0.9921022520597398 1.222823456820164 1.2399189326002582 1.0 14.13436925145936 VAQQPLSLVGCEVVPDPSPDHLYS(ph)FR ddPTM_PC-9_AZD4547_30min_R2 1 VAQQPLSLVGCEVVPDPSPDHLYSFR 26 0 Q8N4X5-2;Q8N4X5;Q8N4X5-4 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 VAQQPLSLVGCEVVPDPS(0.002)PDHLY(0.428)S(0.57)FR 143.48 2.0184e-10 4176200.0 5792.5 7842.8 22742.0 34868.0 26756.0 22566.0 13241.0 26300.0 17178.0 20698.0 True False 7634.394508515246 10377.831725686938 22440.426220641166 26829.7213052299 23041.391242178084 21154.944452699518 14419.42334878414 22235.93931387694 18085.994010417944 19973.369319980873 0.38222867590386883 0.5195834292867757 1.123517312534361 1.3432746811720995 1.1536056272252493 1.0591575268944047 0.7219324450361662 1.1132793349809362 0.9055054117647119 1.0 14.285790101976318 -5.199024709320855 4.7646637980571285 1.0592205555780796 0.4246636947354774 0.7057682074904279 0.15587290697585096 0.1207670555706251 5.563160357762124 0.043850411464563414 0.12276104645301744 6.323758711290108e-06 5.199024709320855 -0.6345568608426022 down VAQQPLSLVGCEVVPDPSPDHLYS(ph)FR ddPTM_PC-9_Lapatinib_30min_R1 3 VAQQPLSLVGCEVVPDPSPDHLYSFR 26 0 Q8N4X5-2;Q8N4X5;Q8N4X5-4 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 VAQQPLSLVGCEVVPDPS(0.002)PDHLY(0.415)S(0.583)FR;VAQQPLSLVGCEVVPDPS(0.001)PDHLY(0.426)S(0.573)FR;VAQQPLSLVGCEVVPDPSPDHLY(0.437)S(0.562)FR 170.8 1.6199e-19 5189000.0 21934.2 20878.4 39913.0 23331.7 29568.1 34209.2 23273.6 25129.6 41261.7 22014.0 True False 21621.414285760347 20830.05734756507 36631.50720863549 25047.591050269555 27828.962491121263 32746.15226154012 24478.59312940061 26297.212956115083 36614.37284103652 25819.090568188833 0.8374196693201752 0.806769599128691 1.4187760452635159 0.970119028170968 1.0778444119719985 1.2682922419384506 0.9480811519968941 1.0185181730806327 1.4181124135390089 1.0 14.656150564707692 -5.212421619075415 24.996823178284828 1.1300745623859516 0.8220941825626271 0.36767798769888294 0.16633935864030894 402.08496883821016 205043.60351617567 0.0406418402185059 0.10752772227657716 6.131664456769684e-06 5.212421619075415 -0.3079803798233245 VAQRS(ph)PVDSGTILR ddPTM_PC-9_AZD4547_30min_R2 1 VAQRSPVDSGTILR 14 1 P49454 P49454 CENPF Centromere protein F 1 VAQRS(0.993)PVDS(0.003)GT(0.003)ILR 51.726000000000006 0.044489 7784900.0 15428.0 9856.3 14638.0 25835.0 14421.0 16278.0 13888.0 14157.0 15523.0 17662.0 True False 20333.783077664768 13042.156224548393 14443.890555700713 19879.139896771096 12418.893074579544 15260.134086725293 15124.005095379047 11969.36094549642 16343.514089167402 17043.65875589441 1.1930409643195008 0.765220450100708 0.847464195485926 1.166365754060645 0.7286518260220725 0.8953555281343393 0.8873684525130812 0.7022764957293525 0.9589205183725668 1.0 14.056947451168403 -6.289997019453187 24.97349335879158 0.8501359718162824 0.9663543282394302 0.14524013632148958 0.14843393836982705 1519.5013233557531 1328790.770865358 0.04492489282680859 0.05094927016246986 5.128649037519711e-07 6.289997019453187 0.11621835642314782 VARPPAAPELGALGS(ph)PDLSSLSLAVSR ddPTM_PC-9_AZD4547_30min_R2 1 VARPPAAPELGALGSPDLSSLSLAVSR 27 1 D6RIV7;D6R992;Q01201 D6RIV7 RELB Transcription factor RelB 1 VARPPAAPELGALGS(0.996)PDLS(0.002)S(0.001)LS(0.001)LAVSR 92.147 8.360200000000001e-08 4039600.0 3823.2 4045.6 5022.0 4202.6 4819.0 5245.6 3559.7 4752.6 7261.2 4894.0 True False 5038.8980724998655 5353.2610839800955 4955.40499868349 3233.7554995227474 4149.965031994925 4917.5918027599355 3876.506403947352 4018.1948738833285 7645.012207966395 4722.662549617663 1.0669612786346134 1.1335260624144075 1.0492820409293628 0.6847314339205848 0.8787341861490607 1.0412752872123066 0.8208306994665935 0.8508325190857926 1.6187928160535883 1.0 12.205384738341154 -8.237536586954683 24.998769055056275 1.3093965580675624 0.9395633280839892 0.37763187732962544 0.18928754268791015 689.0430054724038 720638.9727502288 0.12671300554017145 0.04783751919614943 5.78713232844269e-09 8.237536586954683 -0.36983322998357315 VAS(ph)DMMVLLK ddPTM_PC-9_AZD4547_30min_R2 1 VASDMMVLLK 10 0 I3L506 I3L506 SCPEP1 1 VAS(1)DMMVLLK 76.943 0.013415999999999999 5581800.0 1961.5 955.84 24957.0 23051.0 21730.0 16824.0 6808.2 29795.0 12487.0 14279.0 True False 2585.2161982654566 1264.7965875300413 24626.053873385874 17736.94808439986 18713.164587103092 15771.992620411987 7414.116610768982 25190.86737098719 13147.03732728425 13779.096556189348 0.1876187011044798 0.09179096629248272 1.787203810711686 1.2872359237828774 1.3580835659865842 1.1446318382410539 0.5380698640535094 1.8281944152334035 0.9541291240446974 1.0 13.750193678576142 -5.244573562688443 24.815173049478165 1.2446021815911719 0.1397045426463571 0.5956993814069586 0.36161728523881637 487.10165568108374 716683.9941171621 0.09008886361097627 0.23697735039949244 5.694117665171106e-06 5.244573562688443 -1.1048976389448149 VAS(ph)ETHSEGSEYEELPKR ddPTM_PC-9_AZD4547_30min_R2 1 VASETHSEGSEYEELPKR 18 1 Q5JSZ5;A0A494C0D3 Q5JSZ5 PRRC2B Protein PRRC2B 1 VAS(0.909)ET(0.091)HSEGSEYEELPKR 72.801 0.038707 0.0 5417.6 4396.1 4462.1 5300.5 4823.1 7364.0 4841.5 6076.0 5959.2 4031.4 True False 7140.284106919673 5817.053354579021 4402.929638515655 4078.5516169086573 4153.495817766076 6903.527915876951 5272.384120771724 5137.093812589975 6274.19114605208 3890.2619130626613 1.8354250347371568 1.4952857891255624 1.131782316180709 1.0484002640577386 1.0676648283807142 1.7745663582948983 1.3552774179723464 1.32050075994645 1.612794019082545 1.0 11.925651573024343 -11.71327990501109 2.1713334231897674 0.00034108647785388574 1.3858402424470813 0.17047226262154447 0.2648718545212173 6865634.245135247 1354340.5961333506 33729684.17180523 0.07365736491959904 1.935174332199195e-12 11.71327990501109 1.3854991559692273 VAS(ph)FSIPGSSSR ddPTM_PC-9_AZD4547_30min_R2 2 VASFSIPGSSSR 12 0 Q14573 Q14573 ITPR3 Inositol 1,4,5-trisphosphate receptor type 3 1 VAS(0.949)FS(0.05)IPGSSSR;VAS(0.948)FS(0.051)IPGS(0.001)SSR 139.19 6.212399999999999e-05 84548000.0 66167.0 65061.0 94608.0 82904.0 64993.0 38921.0 62083.0 68869.0 53175.0 48345.0 True False 87206.72964090272 86090.69591280118 93353.43610423106 63791.76365403174 55969.84381084174 36487.26371725242 67608.26672929263 58226.87850218218 55985.72194108596 46652.456265072775 1.8692848484848514 1.845362555481448 2.0010401075949744 1.3673827438275876 1.199719120743158 0.7821080954438252 1.4491898635551332 1.2480988818969176 1.2000594700305354 1.0 15.50966542092983 -5.895669976535583 3.6767543159275755 1.1628194130682656 1.8995677592743738 0.8007734721204893 0.16867698265819517 0.10194512178714715 2.644508225706279 0.0504893041941993 0.07834568594802506 1.2715399904492934e-06 5.895669976535583 0.7367483462061082 VAS(ph)FSIPGSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VASFSIPGSSSR 12 0 Q14573 Q14573 ITPR3 Inositol 1,4,5-trisphosphate receptor type 3 1 VAS(0.92)FS(0.08)IPGSSSR;VAS(0.989)FS(0.011)IPGSSSR;VAS(0.953)FS(0.047)IPGSSSR;VAS(0.999)FS(0.001)IPGSSSR 158.86 0.00019978 92345000.0 135942.0 144193.0 115208.0 96654.0 141079.0 89234.0 82852.0 75691.4 76495.0 69883.0 True False 158954.295623112 158507.52810166104 117954.99564877292 91238.78973649576 113435.58269407524 84554.41195252088 75003.65876346499 73704.58095166752 77613.59466067776 82552.23470647648 1.9254996086815994 1.9200876713422954 1.4288528477536053 1.1052249531572984 1.374106747048192 1.0242534590754977 0.9085600048278369 0.892823570600266 0.9401755741275982 1.0 16.333019649276885 -5.160785214688047 0.6051260426547395 0.923881613832329 2.451982380729751 0.8996816891276047 0.11965707231338857 0.71833329633013 0.2728411341257833 0.06696169617658729 0.7185375900961967 6.905812542708039e-06 5.160785214688047 1.5281007668974218 VAS(ph)FSIPGSSSR ddPTM_PC-9_Lapatinib_30min_R1 3 VASFSIPGSSSR 12 0 Q14573 Q14573 ITPR3 Inositol 1,4,5-trisphosphate receptor type 3 1 VAS(0.921)FS(0.079)IPGSSSR;VAS(0.849)FS(0.151)IPGSSSR;VAS(0.958)FS(0.042)IPGSSSR 198.52 8.494099999999999e-06 94120000.0 152344.0 152824.0 77625.6 49741.5 53797.4 56533.9 56132.8 43602.6 88270.0 24525.5 True False 150171.54662353217 152470.14541747878 71243.52281148123 53399.65584277975 50633.14270175783 54116.0768839576 59039.08172410017 45628.53597511717 78328.10307569228 28764.699996825428 5.220688783130212 5.300599187000244 2.476769193467824 1.8564301330684179 1.7602527649287454 1.881336391129754 2.052483833678638 1.5862684463996808 2.723063445276219 1.0 14.81201180317507 -5.3169082482344825 3.460371632160621 1.8831708860250107 5.339984273370074 0.9153716273749642 0.40987836980810916 0.05440086267963449 1.3029366809615006 0.10282065402118591 0.2584806286960982 4.8204962768408855e-06 5.3169082482344825 3.456813387345064 VAS(ph)GSDLHLTDIDSDSNR ddPTM_PC-9_AZD4547_30min_R2 2 VASGSDLHLTDIDSDSNR 18 0 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 VAS(0.598)GS(0.394)DLHLT(0.008)DIDSDSNR;VAS(0.499)GS(0.499)DLHLT(0.002)DIDSDSNR 157.07 1.1822e-17 3741900.0 5554.4 7209.9 15163.4 23148.0 19518.2 20645.0 14492.5 20678.9 15304.9 19696.2 True False 7320.583661302904 9540.359177720999 14962.323408410446 17811.58623303492 16808.43483865603 19354.06488637694 15782.30442430738 17483.45115884904 16113.885768427393 19006.6420330567 0.385159232681439 0.5019486956785018 0.7872155103667285 0.9371243064428046 0.8843453151494352 1.018279023339104 0.8303573243952564 0.9198600746224135 0.8478028754580544 1.0 14.21421604829655 -5.26528737382934 2.024592229268859 0.9163660667142672 0.3816123863426351 0.9179996490228329 0.05662129994294882 0.08964660169627883 0.6642368918695899 0.015345065353668613 0.06008332626503327 5.428909801886989e-06 5.26528737382934 -0.5347536803716322 down VAS(ph)GSDLHLTDIDSDSNR ddPTM_PC-9_Lapatinib_30min_R1 1 VASGSDLHLTDIDSDSNR 18 0 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 VAS(0.5)GS(0.5)DLHLT(0.001)DIDSDSNR 91.14 0.00071874 3347400.0 9566.0 7640.7 17935.0 10286.0 15513.0 15184.0 9931.6 11425.0 22371.0 9782.2 True False 9429.587085810454 7623.008428593212 16460.453531102074 11042.466753090124 14600.555839731467 14534.615715632795 10445.80965230798 11955.84720901307 19851.34240292639 11473.04023603783 0.8218908756365457 0.6644279346854088 1.4347072085913495 0.9624708469516879 1.2725969350190052 1.2668495374031974 0.9104657037196445 1.0420818687150335 1.7302599829268948 1.0 13.485960120708222 -5.247828944360267 24.953812850725935 1.189741471720264 0.7431593465016102 0.373127614630717 0.23766122855084457 806.2869980435503 1478266.433334889 0.058635166446918144 0.15329660857564792 5.651595304585583e-06 5.247828944360267 -0.4465821252186537 VAS(ph)GVLSPPPAAPPPSSSSVPEAGGPPIKK ddPTM_PC-9_Lapatinib_30min_R1 2 VASGVLSPPPAAPPPSSSSVPEAGGPPIKK 30 1 Q8IXM2-2;F8W038;F8W1H0;H0YIS7;Q8IXM2;Q8IXM2-3 Q8IXM2-2 BAP18;C17orf49;RNASEK-C17orf49 Chromatin complexes subunit BAP18 1 VAS(0.627)GVLS(0.372)PPPAAPPPSSSSVPEAGGPPIKK;VAS(0.582)GVLS(0.418)PPPAAPPPSSSSVPEAGGPPIKK 98.883 9.7265e-13 12869200.0 71896.0 78112.0 100285.0 84324.0 99017.0 92018.0 76660.0 77120.0 89892.0 86118.0 True False 70870.74985588847 77931.13646318713 92039.95441129485 90525.46825661804 93193.01473491204 88082.60464443483 80629.07969973926 80703.27674040155 79767.41635527523 101003.38155497806 0.7016671002971536 0.7715695778043602 0.9112561678065774 0.8962617574080262 0.9226722244362217 0.8720757987344196 0.7982809927591515 0.7990155923291857 0.7897499581423055 1.0 16.62404406910626 -5.038473010463185 3.9161206606953183 0.8659731842527284 0.7109495873823239 0.4461346013460371 0.06274413448691508 0.2053315339917079 6.644019963812811 0.016923093462276613 0.061461187387640885 9.152231347010398e-06 5.038473010463185 -0.15502359687040446 VAS(ph)LPGDFK ddPTM_PC-9_Lapatinib_30min_R1 1 VASLPGDFK 9 0 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4;A8MXE8;Q7Z5J4-4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 VAS(1)LPGDFK 81.017 0.037592 0.0 7734.9 8486.5 9539.7 7892.2 7872.1 10759.0 11715.0 9184.4 9616.0 7767.8 True False 7624.5989075930665 8466.850030659007 8755.382690306918 8472.618715607416 7409.078555144074 10298.862650453973 12321.54537806476 9611.14075330063 8532.944819030905 9110.453880057112 0.8369065919189165 0.9293554571625722 0.9610259604598352 0.9299886511860924 0.8132502126334926 1.1304445185764347 1.3524622966410889 1.0549574016657421 0.936610286531346 1.0 13.153307215110495 -6.773781222856253 24.997293824847514 1.1144277510163965 0.9017750391964134 0.446372530299711 0.11057957302066743 215.82682493599557 437135.2515096802 0.040953033129007076 0.03637015736426579 1.683521926699217e-07 6.773781222856253 -0.21265271181998302 VAS(ph)LTLHNK ddPTM_PC-9_AZD4547_30min_R2 1 VASLTLHNK 9 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 VAS(0.818)LT(0.182)LHNK 63.073 0.033444 7872500.0 73593.0 60698.0 88630.0 120770.0 108960.0 98050.0 90140.0 103770.0 96928.0 100240.0 True False 96994.04317050705 80317.44148591648 87454.70829018673 92928.34237789984 93832.78478650481 91918.91799996415 98162.28537568175 87734.73089737681 102051.41619756598 96730.62811068122 1.0027231815296849 0.8303206859570432 0.9041056591725963 0.9606920185772936 0.9700421326649441 0.9502566022293227 1.014800454550573 0.9070005293151708 1.0550062393970667 1.0 16.561685146470985 -5.844503550234408 3.7669745897400166 0.9772150364760869 0.9038234769429337 0.2474373996354764 0.05375590263987825 0.29237663261568925 8.027839711579583 0.01459555510527512 0.02314222667364756 1.4305282866086156e-06 5.844503550234408 -0.07339155953315313 VAS(ph)LTLHNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VASLTLHNK 9 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 VAS(0.981)LT(0.019)LHNK;VAS(0.992)LT(0.008)LHNK;VAS(0.99)LT(0.01)LHNK 76.332 0.013981 16324100.0 91175.0 85192.0 101077.0 119761.0 118665.0 121929.0 126443.0 129526.0 118971.0 87727.0 True False 106609.12671166546 93649.29874568603 103487.05901665705 113051.17944040048 95413.44509383015 115534.82859626279 114465.403671955 126126.07974414129 120710.72580398097 103631.21065344999 1.0287357065447573 0.9036785168790108 0.9986089939904784 1.0908989553200485 0.9207018280708827 1.114865182677633 1.1045456571450787 1.217066547315709 1.1648105338424162 1.0 16.661099039949754 -6.87338748278607 6.5432088665109465 1.1353215965764598 0.9904248594970788 0.455134194663419 0.07136676620528276 0.18628795697396502 10.024208144204067 0.025046572290401286 0.022105330218196953 1.3384819447539283e-07 6.87338748278607 -0.144896737079381 VAS(ph)LTLHNK ddPTM_PC-9_Lapatinib_30min_R1 3 VASLTLHNK 9 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3;Q9P0K7-4 RAI14 Ankycorbin 1 VAS(1)LTLHNK;VAS(0.999)LT(0.001)LHNK;VAS(0.957)LT(0.043)LHNK 94.69200000000001 0.0065206000000000005 8380100.0 122099.0 96746.0 117494.0 98051.0 96064.0 113509.0 92674.0 91362.0 100437.0 76059.0 True False 120357.84586978561 96521.99058105661 107834.09685995588 105261.99762854735 90413.70438909072 108654.48467240266 97472.2062626354 95607.01205337878 89124.72741150233 89205.69680775316 1.3492170363196458 1.082015992645299 1.2088252288679355 1.1799918771487998 1.013541821033481 1.2180218143081545 1.0926679545219782 1.0717590408987114 0.9990923293113743 1.0 16.444848225276395 -1.5228787475802381 0.15819483823173477 0.9727167154088321 2.051829833987511 0.5122888819789955 0.07601701416897128 57.18388450201989 0.5873152875473415 0.2300653637836647 14.334032751815508 0.0299999998411285 1.5228787475802381 1.079113118578679 VAS(ph)PSPSGSVLFTDEGVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VASPSPSGSVLFTDEGVPK 19 0 P56181-2 P56181-2 NDUFV3 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial 1 VAS(0.702)PS(0.289)PS(0.009)GSVLFTDEGVPK 189.56 2.6144e-47 0.0 10194.0 12688.0 10969.0 8927.8 18663.0 14100.0 12790.0 11046.0 9994.4 11517.0 True False 11919.64285932239 13947.580787929237 11230.54256016415 8427.60431031813 15006.119123466488 13360.571178368615 11578.438608418819 10756.054204204424 10140.54919245283 13604.94093147816 0.8761260279891075 1.0251849573016742 0.82547528994997 0.6194517383621216 1.1029903914353922 0.9820381614047188 0.851046591582727 0.7905991108949115 0.7453578257727189 1.0 13.731843072406903 -7.50972834200773 23.473126152295027 0.8249516280554618 0.9041661236246726 0.03606657072386854 0.13654254963348442 895.189084762141 1597906.7831661704 0.06175481593642197 0.03944698947513877 3.0922290653450824e-08 7.50972834200773 0.07921449556921079 VAS(ph)PSPSGSVLFTDEGVPK ddPTM_PC-9_Lapatinib_30min_R1 1 VASPSPSGSVLFTDEGVPK 19 0 P56181-2 P56181-2 NDUFV3 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial 1 VAS(0.765)PS(0.235)PSGSVLFTDEGVPK 154.31 4.3945e-15 0.0 8345.3 8600.2 6463.6 5322.4 7090.5 5849.6 4622.9 5252.9 6885.2 4429.5 True False 8226.294491659413 8580.286765294717 5932.187758217531 5713.827051005916 6673.450730459354 5599.426244083608 4862.25114197658 5496.968910654251 6109.716271629736 5195.133173062254 1.5834617164992617 1.6516009271494951 1.1418740503086704 1.0998422678812523 1.2845581639874903 1.077821502847644 0.9359242544903891 1.0580997113138644 1.1760461316583313 1.0 12.342945016593104 -5.289158327408038 5.584117336141044 1.097151588733144 1.620272114899935 0.8406870919296616 0.09074723828905497 0.06286857904679594 6.264689798262487 0.025486573234882456 0.05748909578781801 5.138562847868222e-06 5.289158327408038 0.5231205261667911 VAS(ph)PTSGVK ddPTM_PC-9_AZD4547_30min_R2 2 VASPTSGVK 9 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 VAS(0.791)PT(0.16)S(0.049)GVK;VAS(0.814)PT(0.146)S(0.04)GVK 85.963 0.012029999999999999 292440000.0 1250560.0 1267380.0 1375470.0 1650740.0 1512120.0 1589620.0 1399360.0 1447170.0 1403140.0 1367620.0 True False 1648212.0667360942 1677035.8000332955 1357230.3690838683 1270187.3966787655 1302188.2390911337 1490220.8101081378 1523900.329080472 1223543.129158301 1477307.1158329162 1319740.0400711277 1.2488914609632238 1.2707319237983499 1.0284073589301117 0.9624527241064146 0.9867005618931982 1.1291775386520986 1.1546973516074734 0.9271091972721824 1.1193925098713353 1.0 20.331822347517438 -5.261536031556163 24.999868162229593 1.0387124636791831 1.2598117115202825 0.6059493262703912 0.07138986231900817 5.512851207451793 1426456.625650571 0.0190698730305952 0.04431050442101506 5.476006669913359e-06 5.261536031556163 0.22109924784109936 VAS(ph)PTSGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VASPTSGVK 9 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 VAS(0.764)PT(0.182)S(0.054)GVK;VAS(0.797)PT(0.156)S(0.047)GVK 86.344 0.011734999999999999 117779000.0 564370.0 637120.0 553960.0 593050.0 704340.0 547000.0 580590.0 560870.0 542700.0 479150.0 True False 659906.6941843996 700369.0630206089 567168.5073049999 559823.331194041 566329.6331469956 518314.35706153355 525592.3120924067 546147.7567908871 550635.9608124705 566016.1020506859 1.16587971931107 1.237365969772167 1.0020359937643801 0.9890590199921726 1.0005539261077092 0.9157236961699002 0.928581908161582 0.9648979151161682 0.9728273786160979 1.0 19.110483569929023 -5.342034269479098 4.399746731670569 0.9657913243465189 1.2018568963131435 0.895062835955091 0.031578112599938014 0.06077567006411359 2.14100558289367 0.008895498389966871 0.019978091080094164 4.549521591904348e-06 5.342034269479098 0.2360655719666246 VAS(ph)PTSGVK ddPTM_PC-9_Lapatinib_30min_R1 5 VASPTSGVK 9 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 VAS(0.739)PT(0.094)S(0.167)GVK;VAS(0.778)PT(0.18)S(0.042)GVK;VAS(0.842)PT(0.128)S(0.03)GVK;VAS(0.854)PT(0.115)S(0.031)GVK;VAS(0.537)PT(0.355)S(0.108)GVK 102.53 0.0031473000000000004 289735300.0 784712.0 938660.0 1026551.0 969848.0 1111350.0 1046420.0 938698.0 1022185.0 1093295.0 809808.0 True False 773521.8629814422 936486.5904411 942151.9393814527 1041173.8572380845 1045982.5779981678 1001667.0559241608 987299.1893554104 1069679.4467698054 970156.6041932593 949782.2337986669 0.8144202275586174 0.9860013770689405 0.9919662695871909 1.0962237660246557 1.101286737923857 1.0546281245101625 1.0395005867889253 1.1262365294954066 1.021451622982149 1.0 19.857237244477787 -4.306404893593589 1.0697519000312794 1.0664473234308722 0.3909312857049941 0.7676990006395978 0.04026435042135401 1.854475297445355 0.8685158756499599 0.012171927308461275 1.8173466836906418 4.938500549254943e-05 4.306404893593589 -0.6755160377258782 VAS(ph)SPAPPEGPSHPR ddPTM_PC-9_AZD4547_30min_R2 1 VASSPAPPEGPSHPR 15 0 H7BYJ3;O14578;O14578-4;O14578-3 H7BYJ3 CIT Citron Rho-interacting kinase 1 VAS(0.623)S(0.377)PAPPEGPSHPR 62.94 0.023313999999999998 12597000.0 8504.5 8771.4 9820.9 12796.0 13501.0 8831.4 13001.0 23184.0 11700.0 8439.7 True False 11208.754095410943 11606.583515924209 9690.668449137936 9846.079896229261 11626.619194223587 8279.171161905995 14158.06381372574 19601.44551532027 12318.438113976603 8144.228671844756 1.3762818490301598 1.4251298660177714 1.189881674447495 1.2089640766433707 1.4275899735499484 1.0165690939557905 1.7384167837368427 2.406789679553574 1.512535884038033 1.0 12.99156235431549 -7.3529689106117555 7.52698247187337 1.7862756894379017 1.2817548943432426 0.2019129667168501 0.3484441889384479 0.33705587075453447 24.487269845567365 0.1399292609299015 0.09396974655121437 4.436404012195998e-08 7.3529689106117555 -0.5045207950946591 VAS(ph)SPAPPEGPSHPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VASSPAPPEGPSHPR 15 0 H7BYJ3;O14578;O14578-4;O14578-3 H7BYJ3 CIT Citron Rho-interacting kinase 1 VAS(0.554)S(0.446)PAPPEGPSHPR;VAS(0.558)S(0.441)PAPPEGPSHPR 63.54600000000001 0.021974 17612600.0 25682.1 29325.0 22632.0 29761.0 32396.0 22541.0 26298.2 15721.5 20261.9 17952.6 True False 30029.57228540353 32236.192197826644 23171.632712337952 28093.58765646384 26048.236356631867 21358.91027883737 23807.044113519936 15308.82728330617 20558.191955751223 21207.264267296592 1.4160040591238205 1.5200542508227994 1.092627149842735 1.3247153099226732 1.2282695225711158 1.0071506635476142 1.1225891191553843 0.721867143746291 0.9693938688477469 1.0 14.372270905058961 -6.388044784515303 0.592728869990035 0.8878216986163286 1.462624805900727 0.6627630006628124 0.13066454833364724 0.559362311851318 0.42000064392915776 0.09720405968477402 0.1666618107103138 4.092184588823052e-07 6.388044784515303 0.5748031072843983 VAS(ph)SPAPPEGPSHPR ddPTM_PC-9_Lapatinib_30min_R1 2 VASSPAPPEGPSHPR 15 0 H7BYJ3;O14578;O14578-4;O14578-3 H7BYJ3 CIT Citron Rho-interacting kinase 1 VAS(0.5)S(0.5)PAPPEGPSHPR;VAS(0.5)S(0.5)PAPPEGPSHPR 86.005 0.0031812 23359000.0 19682.4 28342.0 30895.0 28181.0 25917.0 25499.0 29809.0 26386.0 26893.0 25597.0 True False 19401.725366689912 28276.375840327277 28354.932358148806 30253.52474906013 24392.61301478248 24408.46721107221 31352.36416344282 27611.989886828815 23864.027144155367 30021.407344141422 0.6462630197273578 0.9418737608197211 0.9444904442057137 1.007731729637385 0.8125073130371624 0.8130354094087945 1.044333591828137 0.9197433541441622 0.7949003479616139 1.0 14.873703988780639 -4.758386074810137 24.99741962328199 0.9180528140377789 0.6462626484603128 0.49277405461020773 0.08325189338618293 75.04571124099911 614292.2992776297 0.020970908451447237 0.14398046976742943 1.744270858851281e-05 4.758386074810137 -0.27179016557746616 VASEAPLEHKPQVEAS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 4 VASEAPLEHKPQVEASSPR 19 1 Q8TD19 Q8TD19 NEK9 Serine/threonine-protein kinase Nek9 1 VASEAPLEHKPQVEAS(0.5)S(0.5)PR;VASEAPLEHKPQVEAS(0.5)S(0.5)PR;VASEAPLEHKPQVEAS(0.5)S(0.5)PR;VASEAPLEHKPQVEAS(0.5)S(0.5)PR 83.751 0.00060722 202745200.0 619956.0 669669.0 935780.0 1230574.0 1021732.0 979733.0 845943.0 1170878.0 800907.0 988669.0 True False 817089.1121141245 886126.408158954 923370.9457722087 946884.176478777 879882.1481780946 918470.1406308892 921230.2881912636 989945.7091997581 843241.308935953 954055.9992374248 0.8564372665411908 0.9287991573526431 0.9678372616599628 0.9924828073358584 0.9222541956461495 0.9627004508802636 0.9655935174954103 1.0376180328943163 0.883848861712472 1.0 19.863714423530347 -4.812482989481887 2.1984700900184313 0.9670346674059838 0.8318462609151535 0.4191005987461722 0.03962005021885914 0.5578702108773076 3.3309666460579104 0.009996243547375652 0.14652733262606565 1.539986843337668e-05 4.812482989481887 -0.1351884064908303 VASEAPLEHKPQVEAS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VASEAPLEHKPQVEASSPR 19 1 Q8TD19 Q8TD19 NEK9 Serine/threonine-protein kinase Nek9 1 VASEAPLEHKPQVEAS(0.5)S(0.5)PR;VASEAPLEHKPQVEAS(0.747)S(0.253)PR;VASEAPLEHKPQVEAS(0.5)S(0.5)PR;VASEAPLEHKPQVEAS(0.5)S(0.5)PR 86.411 0.0005836 138960000.0 354231.0 381053.0 434376.0 468303.0 569729.0 546711.0 506981.0 481670.0 470212.0 414743.0 True False 414195.31191883684 418881.42354845424 444733.17122015345 442065.5011688119 458094.6922838476 518040.5127302895 458956.0894554179 469026.67287155124 477087.96094629396 489932.62279621884 0.8454128029990688 0.8549776113248996 0.9077435355945556 0.902298562291663 0.9350156959733342 1.0573709294426017 0.9367738911444456 0.9573289286078769 0.9737827994049144 1.0 18.902223832967877 -5.920968045587884 1.1578297588582789 0.9792044482534229 0.8503651382280757 0.6961023986329683 0.0337151215205488 0.30526015174650506 0.8251088712146446 0.013236979037394398 0.028875799386390413 1.199587562859758e-06 5.920968045587884 -0.1288393100253472 VASEAPLEHKPQVEAS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 4 VASEAPLEHKPQVEASSPR 19 1 Q8TD19 Q8TD19 NEK9 Serine/threonine-protein kinase Nek9 1 VASEAPLEHKPQVEAS(0.5)S(0.5)PR;VASEAPLEHKPQVEAS(0.5)S(0.5)PR;VASEAPLEHKPQVEAS(0.5)S(0.5)PR;VASEAPLEHKPQVEAS(0.5)S(0.5)PR 103.92 0.00012696 246521000.0 651933.0 556166.0 673620.0 590843.0 647430.0 669526.0 583572.0 589680.0 738109.0 426307.0 True False 642636.3158701309 554878.2317977375 618237.563848396 634295.5652144675 609349.4402963542 640891.933721335 613786.5027202744 617078.685532677 654975.3917876536 499993.5969316292 1.2852890913281179 1.109770675470497 1.2364909623691358 1.2686073763884684 1.218714487617086 1.2818002823523613 1.2275887261096379 1.2341731760558095 1.3099675591989974 1.0 18.931550093855904 -10.630575545908528 4.6352142277466815 0.9999847430186739 1.238069196971515 0.6579717015139325 0.052160048525312266 36736974.66409627 0.26747518763840483 6824.539411413758 0.012489419784095332 2.3411241991261062e-11 10.630575545908528 0.23808445395284106 VASEAPLEHKPQVEASS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 VASEAPLEHKPQVEASSPR 19 1 Q8TD19 Q8TD19 NEK9 Serine/threonine-protein kinase Nek9 1 VASEAPLEHKPQVEAS(0.407)S(0.593)PR 55.631 0.014387 56160000.0 10219.0 12697.0 21212.0 17970.0 19887.0 21878.0 10080.0 20441.0 10610.0 19740.0 True False 13468.429431595554 16801.056946632205 20930.715020325406 13827.294133732394 17126.0333246074 20509.96520146061 10977.100472452545 17282.313137450885 11170.8229392557 19048.908608388367 0.7070446768622011 0.8819957768726814 1.0987881484773552 0.72588379827931 0.8990558817141782 1.0767002783786181 0.5762587609674747 0.90726001645262 0.5864285019634418 1.0 14.217420721605524 -7.260033647628808 24.999679956445927 0.7597584971857033 0.8988240516306831 0.12646051301241812 0.16786442269873816 260.5344308722202 4633428.759137716 0.06385767713883105 0.04671742234586952 5.4949829898774234e-08 7.260033647628808 0.1390655544449798 VASEAPLEHKPQVEASS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VASEAPLEHKPQVEASSPR 19 1 Q8TD19 Q8TD19 NEK9 Serine/threonine-protein kinase Nek9 1 VASEAPLEHKPQVEAS(0.429)S(0.571)PR 80.277 0.001192 35543000.0 11038.0 13046.0 16366.0 16725.0 16163.0 16396.0 16392.0 14204.0 14409.0 11625.0 True False 12906.51538956255 14341.120661989646 16756.22750840064 15787.952473181604 12995.976177066324 15536.164896491613 14839.231092197126 13831.160050382005 14619.70436585015 13732.52047655063 0.9398504383518999 1.0443181706139268 1.2201858746188095 1.1496762375225136 0.9463649589496689 1.1313411054453442 1.0805904944788753 1.0071829183870369 1.064604592493742 1.0 13.745308822608916 -7.74894502918757 24.304558661072758 1.0269203212987967 1.0780334027913987 0.06700930169724406 0.08263805058345096 473.651114027458 921373.6508202185 0.04116146556477521 0.023526362645436096 1.782604386271451e-08 7.74894502918757 0.051113081492601964 VASEAPLEHKPQVEASS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 VASEAPLEHKPQVEASSPR 19 1 Q8TD19 Q8TD19 NEK9 Serine/threonine-protein kinase Nek9 1 VASEAPLEHKPQVEAS(0.42)S(0.58)PR 60.761 0.008963500000000001 8647600.0 11923.0 13972.0 15064.0 14161.0 13193.0 13289.0 10361.0 12096.0 14512.0 9422.4 True False 11752.97583358958 13939.648692437115 13825.496068721595 15202.447179711182 12417.013678435978 12720.660448172028 10897.441883237652 12658.024318619002 12877.50574186527 11051.049285441199 1.0635167331190087 1.2613868902748806 1.2510573169676737 1.3756564455593452 1.1236049498751508 1.1510816864178135 0.9861001975255046 1.1454137966152096 1.165274482924465 1.0 13.431895738037959 -6.493898399042428 22.428910553533605 1.0972116373256193 1.2416599379741817 0.37675030557214073 0.09045516321059215 217.6205940636732 168423.92073307466 0.02825454643850104 0.03194887854545965 3.207019502449445e-07 6.493898399042428 0.1444483006485624 VASETHS(ph)EGSEYEELPK ddPTM_PC-9_AZD4547_30min_R2 2 VASETHSEGSEYEELPK 17 0 Q5JSZ5;A0A494C0D3 Q5JSZ5 PRRC2B Protein PRRC2B 1 VAS(0.008)ET(0.034)HS(0.957)EGSEYEELPK;VAS(0.004)ET(0.014)HS(0.972)EGS(0.011)EYEELPK 97.77600000000001 0.00080521 8163500.0 41718.0 37645.0 72664.0 98646.0 87494.0 76167.0 65465.0 101831.0 77508.0 79640.0 True False 54983.45621169425 49813.01006190196 71700.42788218576 75904.68876550737 75346.96835637346 71404.26544929374 71291.25817749051 86095.35879358955 81604.91464428185 76851.82784052953 0.715447605563618 0.6481694900642553 0.9329697145390853 0.9876757768600181 0.9804186897508969 0.9291160334853755 0.927645576959114 1.1202773078116073 1.061847413878238 1.0 16.229791952869633 -5.358788093313486 3.6984594772874555 0.9971628622674539 0.679923488277581 0.8286797247603619 0.05702824085741514 0.09470244665840213 2.3586533331896162 0.016984800472607937 0.039702143655544836 4.377356388000739e-06 5.358788093313486 -0.3172393739898729 VASETHS(ph)EGSEYEELPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VASETHSEGSEYEELPK 17 0 Q5JSZ5;A0A494C0D3 Q5JSZ5 PRRC2B Protein PRRC2B 1 VASET(0.001)HS(0.93)EGS(0.069)EYEELPK;VAS(0.015)ET(0.015)HS(0.966)EGS(0.003)EYEELPK 102.47 0.00054439 8349900.0 45892.0 55193.0 96749.0 120193.0 101314.0 70862.0 63629.0 65604.0 56782.0 49492.0 True False 53660.60919168365 60672.19628217042 99055.86308262598 113458.97588096342 81462.24898863448 67145.87197457848 57601.60048593289 63881.96451318379 57612.32932900991 58464.50782154359 0.9178322231921748 1.037761174136034 1.6942905494900082 1.9406470713357296 1.3933624351596174 1.1484894763765698 0.9852404926037411 1.0926623158819087 0.9854240029671529 1.0 15.835273449902132 -6.8619108064520224 3.513270769664965 1.0284662901201862 1.4246342738898548 0.2998586162156912 0.2748192227196587 0.3417445369909283 8.215350414482185 0.1154649310329735 0.10191787086648992 1.3743241988716054e-07 6.8619108064520224 0.39616798376966855 VASETHS(ph)EGSEYEELPK ddPTM_PC-9_Lapatinib_30min_R1 2 VASETHSEGSEYEELPK 17 0 Q5JSZ5;A0A494C0D3 Q5JSZ5 PRRC2B Protein PRRC2B 1 VAS(0.002)ET(0.013)HS(0.985)EGSEYEELPK;VASET(0.001)HS(0.998)EGS(0.001)EYEELPK 116.73 7.6961e-05 10765600.0 119334.0 96215.0 154552.0 103820.0 117873.0 88273.0 76052.0 68650.0 82271.0 58450.0 True False 117632.27527682435 95992.22007893209 141845.33114797284 111455.26913336759 110939.94188723434 84497.76956441348 79989.60043470608 71839.72961914659 73004.77362796293 68553.0046202706 1.7159317221530124 1.4002627690887224 2.0691336861700482 1.625826172765754 1.6183089640162942 1.2325903150775703 1.1668285128826252 1.0479442880305807 1.0649390793642322 1.0 16.064932279044374 -6.843094682367149 1.755641610705133 1.0623137270896355 1.7106323900422042 0.7823412518440155 0.15644538667943175 0.16516266270869054 1.0488496104038025 0.06810376146828519 0.05845139113850722 1.4351765103750133e-07 6.843094682367149 0.6483186629525688 VASGPSPGEGIS(ph)PQSAQAPQAPGDNHVVPVLR ddPTM_PC-9_AZD4547_30min_R2 1 VASGPSPGEGISPQSAQAPQAPGDNHVVPVLR 32 0 Q14764 Q14764 MVP Major vault protein 1 VAS(0.002)GPS(0.007)PGEGIS(0.93)PQS(0.061)AQAPQAPGDNHVVPVLR 63.783 7.5196e-05 18394000.0 7016.5 6032.2 6818.7 12438.0 9922.7 12367.0 7745.0 9565.6 7108.7 6224.4 True False 9247.601047733662 7981.990683899723 6728.27958274057 9570.611265184396 8545.104383269567 11593.689534987812 8434.289995946914 8087.456315620584 7484.451369301314 6006.485650559911 1.5396026205226383 1.3288953222015372 1.1201690929059949 1.5933795270604276 1.4226462661195256 1.93019516061061 1.4041971439922925 1.3464539476368664 1.2460616414864207 1.0 12.552305412458997 -8.439446264638828 1.5117629096160403 1.0089810866533844 1.4731356908096256 0.36749559171726254 0.19609938748179476 0.4565889398020104 2.252214986936193 0.19760547781564372 0.05872419766212547 3.6354128281419228e-09 8.439446264638828 0.4641546041562412 VASGPSPGEGIS(ph)PQSAQAPQAPGDNHVVPVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VASGPSPGEGISPQSAQAPQAPGDNHVVPVLR 32 0 Q14764 Q14764 MVP Major vault protein 1 VASGPS(0.001)PGEGIS(0.784)PQS(0.215)AQAPQAPGDNHVVPVLR;VASGPS(0.001)PGEGIS(0.986)PQS(0.013)AQAPQAPGDNHVVPVLR;VAS(0.001)GPS(0.002)PGEGIS(0.539)PQS(0.459)AQAPQAPGDNHVVPVLR 130.71 4.2035e-16 69009900.0 36283.4 35385.8 28810.300000000003 51006.1 57511.4 45314.1 50562.9 32960.2 38829.2 41577.8 True False 42425.46299018426 38898.668367394894 29497.24681567119 48148.393581007345 46242.454019039295 42937.748825086 45773.21606830492 32095.029674218593 39397.00359237064 49115.5260103163 0.863789242148667 0.7919831370476325 0.6005686839122021 0.9803090283690371 0.9415037926973735 0.8742194640462017 0.931950032637147 0.6534599602471386 0.8021293222859026 1.0 15.58389152949412 -5.7766772255160435 24.99992110301557 0.8729936399794457 0.7561005489038619 0.21906950048604246 0.11229855466926705 415.5395511766539 681752.6598579687 0.033406184278667296 0.04975706602120718 1.6723330567609015e-06 5.7766772255160435 -0.11689309107558377 VASGPSPGEGIS(ph)PQSAQAPQAPGDNHVVPVLR ddPTM_PC-9_Lapatinib_30min_R1 1 VASGPSPGEGISPQSAQAPQAPGDNHVVPVLR 32 0 Q14764 Q14764 MVP Major vault protein 1 VASGPS(0.003)PGEGIS(0.896)PQS(0.1)AQAPQAPGDNHVVPVLR 126.15 1.5143e-16 68932000.0 9095.9 11688.0 14350.0 9551.3 11213.0 13399.0 8708.4 9267.2 16189.0 8696.1 True False 8966.190798016236 11660.937154108575 13170.198392601887 10253.734464202767 10553.473385606203 12825.95600459455 9159.278341471549 9697.787943576897 14365.624342272384 10199.209298175105 0.8791064616764471 1.1433177625048845 1.2912960218355718 1.0053460189347638 1.0347344658859472 1.2575441516715846 0.898038080570655 0.9508372325795957 1.4085037302688508 1.0 13.316169689999269 -10.717336764589913 6.197225203142067 0.9999990454199 1.0937436915225855 0.028498734264694736 0.1683678426224323 2.163056725916572e-06 2.8140505042229534e-07 0.15879511549479008 0.038513080051898504 1.9171815257377575e-11 10.717336764589913 0.09374464610268551 VASGPSPGEGISPQS(ph)AQAPQAPGDNHVVPVLR ddPTM_PC-9_AZD4547_30min_R2 2 VASGPSPGEGISPQSAQAPQAPGDNHVVPVLR 32 0 Q14764 Q14764 MVP Major vault protein 1 VASGPSPGEGIS(0.032)PQS(0.968)AQAPQAPGDNHVVPVLR;VASGPSPGEGIS(0.395)PQS(0.605)AQAPQAPGDNHVVPVLR 140.06 2.9063999999999998e-18 167509000.0 50223.0 45231.0 62384.0 84128.0 69228.0 68251.0 56269.0 55580.0 59784.0 55334.0 True False 66192.86929670455 59851.03620958664 61556.74739901849 64733.58936464319 59616.8871622628 63983.25418067867 61276.8319925032 46991.38810134146 62944.06018854501 53396.77350235876 1.239641741532951 1.1208736461753213 1.1528177333841954 1.212312750727975 1.1164885676028584 1.1982606810101037 1.1475755550997166 0.8800417144917128 1.1787989434560968 1.0 15.704464949312873 -7.553427777546019 24.949104141578125 1.0204137504352375 1.1695631170158634 0.45074587131157884 0.07631315369285 169.31196100025605 138273.54491266058 0.03270564413115981 0.018882876296074148 2.796225696626126e-08 7.553427777546019 0.14914936658062583 VASGPSPGEGISPQS(ph)AQAPQAPGDNHVVPVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VASGPSPGEGISPQSAQAPQAPGDNHVVPVLR 32 0 Q14764 Q14764 MVP Major vault protein 1 VASGPS(0.001)PGEGIS(0.364)PQS(0.635)AQAPQAPGDNHVVPVLR;VAS(0.002)GPS(0.006)PGEGIS(0.216)PQS(0.776)AQAPQAPGDNHVVPVLR 92.449 3.2387e-10 61046300.0 31986.2 43582.8 52011.8 33334.8 52283.0 44508.4 49372.7 34072.7 50059.9 46974.5 True False 37400.83190375301 47909.41235530912 53251.95856784994 31467.159228879762 42038.52146665584 42174.30115143983 44695.76042860673 33178.32772800981 50791.93133347369 55490.60500006261 0.674002957864864 0.8633788071918672 0.9596571990481967 0.5670718354727662 0.7575790796767922 0.7600259746923329 0.8054653653272711 0.5979089204014333 0.9153248794713335 1.0 15.759955911964191 -8.498153830920423 11.142444270037833 0.999999046174455 0.7556424329531828 0.3739580639957426 0.11083248341186817 0.7319089323401093 326.99833489442256 0.10681407520383057 0.02758378918469016 3.175748993215547e-09 8.498153830920423 -0.24435661322127222 VASGPSPGEGISPQS(ph)AQAPQAPGDNHVVPVLR ddPTM_PC-9_Lapatinib_30min_R1 3 VASGPSPGEGISPQSAQAPQAPGDNHVVPVLR 32 0 Q14764 Q14764 MVP Major vault protein 1 VAS(0.002)GPS(0.008)PGEGIS(0.426)PQS(0.565)AQAPQAPGDNHVVPVLR;VASGPSPGEGIS(0.136)PQS(0.864)AQAPQAPGDNHVVPVLR;VAS(0.005)GPS(0.018)PGEGIS(0.222)PQS(0.754)AQAPQAPGDNHVVPVLR 138.29 8.8412e-18 96869000.0 25858.11 27689.0 34433.0 24642.0 28285.600000000002 29716.5 26081.7 29690.199999999997 30257.100000000002 25117.2 True False 25489.368609603385 27624.88782170709 31602.05165522374 26454.254883302237 26621.896619629235 28445.594567544893 27432.08280726179 31069.71508140394 26849.226776611875 29458.674553434746 0.8652585018164519 0.9377505349603773 1.0727587759558275 0.8980123947979116 0.9037031374694094 0.965610130080624 0.9312056032087613 1.0546881539102158 0.9114200548266479 1.0 14.846404899597191 VASGS(ph)DLHLTDIDSDSNR ddPTM_PC-9_Lapatinib_30min_R1 1 VASGSDLHLTDIDSDSNR 18 0 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 VAS(0.233)GS(0.765)DLHLT(0.001)DIDSDSNR 62.303000000000004 0.011968000000000001 2788900.0 14839.0 11994.0 19430.0 14554.0 17601.0 18927.0 13740.0 11888.0 19013.0 10485.0 True False 14627.393138860678 11966.228629909161 17832.54040196896 15624.349710720742 16565.743784897408 18117.53633099195 14451.389969663676 12440.359879277668 16871.555724234044 12297.318279615698 1.1894782916294329 0.973076272226331 1.4501161957829916 1.2705493470572364 1.347102141151957 1.4732916493691124 1.175165970422886 1.0116319344111862 1.3719703223588757 1.0 13.586056115721949 -9.797541506017234 0.5746711445182984 0.9752886736833545 1.259348104765857 0.17190172367270684 0.1613180612893432 13.459355377560897 4.268555443993195 0.9359499170385112 0.07193540055408253 1.5938905435020298e-10 9.797541506017234 0.28405943108250253 VASGVLS(ph)PPPAAPPPSSSSVPEAGGPPIKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VASGVLSPPPAAPPPSSSSVPEAGGPPIKK 30 1 Q8IXM2-2;F8W038;F8W1H0;H0YIS7;Q8IXM2;Q8IXM2-3 Q8IXM2-2 BAP18;C17orf49;RNASEK-C17orf49 Chromatin complexes subunit BAP18 1 VAS(0.322)GVLS(0.676)PPPAAPPPS(0.001)S(0.001)SSVPEAGGPPIKK 67.498 5.6722e-05 6053500.0 24139.0 26061.0 28301.0 31091.0 30576.0 29967.0 27852.0 31025.0 26125.0 23689.0 True False 28225.25593301779 28648.16384885116 28975.803172140204 29349.072068382004 24584.852291652525 28395.477766111508 25213.656928982087 30210.62662370474 26507.02870135578 27983.628177979175 1.008634611405706 1.0237473020526666 1.0354555523626414 1.048794383691723 0.8785441307070679 1.0147175193121107 0.9010145778317328 1.0795821911140897 0.9472334513869306 1.0 14.77229540477681 VASPS(ph)PSGSVLFTDEGVPK ddPTM_PC-9_AZD4547_30min_R2 1 VASPSPSGSVLFTDEGVPK 19 0 P56181-2 P56181-2 NDUFV3 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial 1 VAS(0.39)PS(0.553)PS(0.023)GS(0.033)VLFTDEGVPK 182.15 3.8133e-37 0.0 7402.9 10181.0 15328.0 16062.0 15487.0 11884.0 9919.5 14413.0 11892.0 11700.0 True False 9756.868210114368 13471.80914969382 15124.740704862714 12359.154055426263 13336.897375078943 11140.891601341898 10802.31628338224 12185.802027791186 12520.586842000823 11290.386561202844 0.8641748586042124 1.1932106200851438 1.3396122996209767 1.0946617273403219 1.1812613591910595 0.9867590928751142 0.9567711632214827 1.07930777761545 1.1089599788394595 1.0 13.462807261619895 -6.759712883562061 24.999236031288483 1.0269670562911313 1.1470137420922666 0.16930126822724212 0.11826816913875894 81.71131799714829 1183165.52981942 0.041291551140044916 0.03928372439907638 1.738950086158261e-07 6.759712883562061 0.12004668580113531 VASPSQGQVGSS(ph)SPKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VASPSQGQVGSSSPKR 16 1 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 VASPSQGQVGS(0.188)S(0.488)S(0.325)PKR 59.181999999999995 0.023166 16700000.0 14280.0 10219.0 18090.0 13994.0 22425.0 14788.0 14547.0 15783.0 18129.0 14264.0 True False 16697.3219571438 11233.474784981774 18521.334206707048 13209.96154916013 18030.98222920945 14012.491247213835 13169.002848840388 15368.712973470809 18394.102328301575 16849.95028623812 0.9909419122014278 0.6666770283682382 1.0991922167173396 0.7839762922000499 1.070091123291676 0.8316043079758089 0.7815455016265492 0.9120924817222111 1.0916413411216181 1.0 14.040456714463792 -8.169397240414089 5.722275981819096 1.0442719456050003 0.8868642618356535 0.18530943679175504 0.1292879705809582 0.3375732308905413 16.310410357778707 0.08559020937131401 0.031131844280801457 6.770219659585282e-09 8.169397240414089 -0.15740768376934677 VASPSQGQVGSSS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 VASPSQGQVGSSSPK 15 0 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 VASPSQGQVGSS(0.079)S(0.92)PK;VASPSQGQVGSS(0.037)S(0.963)PK 203.05 1.0173e-12 11386000.0 42781.0 55613.0 48195.0 49338.0 52998.0 52780.0 58171.0 50607.0 52647.0 46351.0 True False 56384.46809992067 73588.81467851133 47555.90280994642 37963.88636450132 45640.14251207038 49479.658256380455 63348.10630784091 42786.850983169956 55429.81293901928 44728.265598146405 1.2606003686013103 1.6452418553327708 1.0632181278211064 0.8487672360377548 1.0203870394196946 1.1062279655759992 1.416288010739816 0.9565953522003566 1.2392569261911277 1.0 15.448899196432853 -5.279499896618232 24.384542518545118 1.08216024293935 1.4529211034455702 0.4306643809988837 0.1708913217650541 481.0053874504991 649432.8627010118 0.04526849894655872 0.09456780832391477 5.254121401819652e-06 5.279499896618232 0.37076086050622026 VASPSQGQVGSSS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VASPSQGQVGSSSPK 15 0 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 VASPSQGQVGSS(0.228)S(0.772)PK;VASPSQGQVGSS(0.208)S(0.792)PK 224.64 8.111399999999997e-79 3816100.0 32782.0 40788.0 30313.0 36978.0 42264.0 26855.0 35386.0 34456.0 28285.0 31855.0 True False 38331.34512598656 44837.163081498875 31035.77688269267 34906.242544293535 33982.67259466256 25446.676524474384 32033.98190754561 33551.566509149714 28698.61461503724 37630.05933595873 1.0186363190067493 1.191525176221371 0.824760243017617 0.9276159315257216 0.9030725221894407 0.676232697304251 0.8512870421369336 0.8916160936554339 0.7626513250701485 1.0 15.19959794383236 -5.270115150489998 24.93275651302077 0.8486261300046732 1.1050807501760613 0.5360339802089072 0.09305863761209715 385.0549707014349 1106587.2015255485 0.02376827451374994 0.05072412157774455 5.368894245934497e-06 5.270115150489998 0.2564546201713881 VASPSQGQVGSSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 VASPSQGQVGSSSPK 15 0 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 VASPSQGQVGSS(0.021)S(0.979)PK;VASPSQGQVGSS(0.187)S(0.813)PK 211.9 1.048e-13 14479600.0 41719.0 43823.0 21315.3 24549.0 26116.0 18013.300000000003 23339.0 23574.0 21277.0 17443.4 True False 41124.079409672384 43721.5305359771 19562.838313437413 26354.415353063334 24579.90822603153 17242.913150053217 24547.37922139596 24669.334101118093 18880.560203257133 20458.46844813051 2.0101250254356304 2.1370871747719886 0.9562220340704468 1.2881910207443508 1.2014539743456523 0.8428252189928163 1.199863972400099 1.2058250676810742 0.9228726114628798 1.0 14.32041052634381 -5.258856320742423 24.99537481062993 1.0924971654014657 2.0736062001614135 0.8876524254260791 0.14171574584470117 63.3039460927898 612561.871851985 0.0361547873485906 0.08699681837688937 5.509899523093124e-06 5.258856320742423 0.9811090347599478 VASPSQGQVGSSS(ph)PKR ddPTM_PC-9_AZD4547_30min_R2 1 VASPSQGQVGSSSPKR 16 1 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 VASPSQGQVGS(0.278)S(0.278)S(0.444)PKR 92.26899999999999 0.0045037 2525400.0 7948.7 11007.0 10725.0 13135.0 13292.0 10768.0 10301.0 13361.0 10905.0 10879.0 True False 10476.221256769119 14564.797496383457 10582.779492409489 10106.928683727048 11446.635236620994 10094.675257762496 11217.769044318815 11296.364455236115 11481.416037001256 10498.129521309887 0.9979131268578562 1.387370718452153 1.0080633384192652 0.9627361391580519 1.090349972667584 0.961568938282917 1.0685493088600355 1.0760359197613165 1.0936630200356567 1.0 13.357844681658174 VASPSQGQVGSSS(ph)PKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VASPSQGQVGSSSPKR 16 1 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 VASPSQGQVGS(0.092)S(0.245)S(0.663)PKR;VASPSQGQVGS(0.071)S(0.071)S(0.859)PKR 85.177 0.0021968000000000005 29061000.0 27183.0 28560.0 29295.0 37774.0 41362.0 33650.0 32735.0 36957.0 31438.0 30964.0 True False 31784.545011277292 31395.248053535535 29993.503901906184 35657.64524496033 33257.41301960141 31885.334762560546 29634.103819123546 35986.91790917828 31897.721275147294 36577.52808911087 0.8689637236787346 0.8583206600798674 0.819998110009934 0.9748511478985266 0.9092307423995155 0.8717192338662385 0.8101724027640244 0.9838531959159805 0.8720578710906177 1.0 15.158669960538731 -14.522878725515392 0.16472624428401272 1.4365645010457813 0.8574685863931797 0.3031884493156841 0.05369377205687614 172.2873549231676 1.5989004266790723 24.50217110676461 0.21411389931951016 3.000000136531409e-15 14.522878725515392 -0.5790959146526016 VASPSQGQVGSSS(ph)PKR ddPTM_PC-9_Lapatinib_30min_R1 4 VASPSQGQVGSSSPKR 16 1 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 VASPSQGQVGS(0.136)S(0.088)S(0.776)PKR;VASPSQGQVGS(0.181)S(0.181)S(0.639)PKR;VASPSQGQVGS(0.005)S(0.012)S(0.984)PKR;VASPSQGQVGS(0.087)S(0.289)S(0.624)PKR 89.756 0.0016859000000000002 59984900.0 82526.0 68414.7 68291.0 49096.7 58737.0 52685.9 47948.0 51033.9 61594.0 46454.4 True False 81349.16410658493 68256.28996553675 62676.37759088325 52707.435099789975 55282.20514138509 50432.646873831516 50430.51282863419 53405.1213024116 54656.635106425674 54483.9811434029 1.4930840661674913 1.252777211450185 1.150363396278216 0.9673932409796372 1.0146506180574664 0.9256417357074515 0.925602567402336 0.980198586477157 1.0031688940382006 1.0 15.733544504448586 -4.827138050454839 0.9404182510640484 0.9624066712786788 1.7489742752798518 0.9529143734578237 0.03705180481145749 0.3712076651186979 0.27161504279490284 0.012830288539536126 0.2952746485120794 1.4888877253940392e-05 4.827138050454839 0.786567604001173 VASPTS(ph)GVK ddPTM_PC-9_Lapatinib_30min_R1 1 VASPTSGVK 9 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 VAS(0.106)PT(0.252)S(0.641)GVK 86.882 0.01132 8325100.0 57315.0 63825.0 73826.0 53287.0 80220.0 75600.0 60205.0 66696.0 81613.0 59820.0 True False 56497.67758971629 63677.21713389627 67756.31125660116 57205.90374022103 75501.61731858815 72366.76423220758 63322.120314672604 69794.93964571856 72420.8845170101 70159.80729486022 0.8052712766480932 0.9076025090302827 0.9657425507433636 0.8153657477963431 1.0761377522215523 1.0314561430887659 0.9025412519813387 0.9947994776039188 1.0322275289703584 1.0 16.098357164744705 -2.957164558846303 0.4236098897887756 1.0019831125880092 4.9292301968492835e-11 0.43398663935270354 0.06605502534030847 24.235489424263303 0.9831923886631276 0.04673548799951305 16.972184714820017 0.0011036603518962274 2.957164558846303 -1.0019831125387169 VASS(ph)PAPPEGPSHPR ddPTM_PC-9_AZD4547_30min_R2 1 VASSPAPPEGPSHPR 15 0 H7BYJ3;O14578;O14578-4;O14578-3 H7BYJ3 CIT Citron Rho-interacting kinase 1 VAS(0.007)S(0.993)PAPPEGPSHPR 183.81 5.1909e-07 4443900.0 6252.8 7331.0 11068.0 12551.0 8348.3 12122.0 9004.4 14050.0 11101.0 10328.0 True False 8241.060333680469 9700.602384481428 10921.231088297272 9657.560861016993 7189.28264714738 11364.009423718144 9805.774156165842 11878.895336881018 11687.776196859335 9966.41986359854 0.8268827168098956 0.9733286894637074 1.095802829678699 0.9690100350167239 0.7213505697673439 1.1402298497602108 0.9838813024504977 1.1918919230231937 1.1727156147161626 1.0 13.282859637568956 -6.856525282657088 21.851562701072297 1.1026291163088155 0.9328071441712421 0.39166702216206883 0.11153072823774353 7.389295430462314 1689.505038376654 0.040612289282301185 0.03581671811749834 1.3914727872453875e-07 6.856525282657088 -0.16982197213757344 VASS(ph)PAPPEGPSHPR ddPTM_PC-9_Lapatinib_30min_R1 1 VASSPAPPEGPSHPR 15 0 H7BYJ3;O14578;O14578-4;O14578-3 H7BYJ3 CIT Citron Rho-interacting kinase 1 VAS(0.264)S(0.736)PAPPEGPSHPR 161.04 0.00029486 3780200.0 6870.9 9121.0 9937.2 10568.0 10684.0 8210.9 7621.3 7684.6 7826.1 5462.3 True False 6772.919706031254 9099.880884892567 9120.20177470129 11345.205973814549 10055.588125552185 7859.738947542756 8015.893622692702 8041.6545700115485 6944.64220551349 6406.451276942755 1.0572030307024176 1.420424583207812 1.4235965248850804 1.7709033415499 1.569603465454099 1.2268475334902618 1.2512221315945127 1.2552432263012754 1.0840076518661306 1.0 12.645309711259909 -6.874238787734353 5.757510069659354 1.178806746850468 1.462497735378117 0.38254374425223425 0.18076483133799057 0.25398093632696217 11.872467299493223 0.06846795459622085 0.06042832779463679 1.3358608194639914e-07 6.874238787734353 0.28369098852764907 VASS(ph)PVMVSNPATR ddPTM_PC-9_AZD4547_30min_R2 1 VASSPVMVSNPATR 14 0 P51610;A6NEM2;P51610-2;P51610-4 P51610 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 VAS(0.147)S(0.853)PVMVSNPATR 94.71700000000001 0.015133 0.0 17890.0 25906.0 17526.0 26104.0 24857.0 29931.0 20739.0 30603.0 20919.0 31262.0 True False 23578.647864883493 34279.60788055874 17293.593788715036 20086.12610277967 21406.03461305207 28059.409838418385 22584.730823233447 25874.009536980066 22024.735633015076 30167.52689541225 0.7815903486761864 1.1363081899090586 0.5732519556100892 0.665819447925454 0.709572073549967 0.9301196593176997 0.7486437619342285 0.8576775161809792 0.7300809147986375 1.0 14.880708810141844 -9.278411713371407 11.541201309508548 0.9999999985487735 0.7947230653648286 0.15049582961885422 0.14777231216510042 14249474.839828022 881207.1981457341 0.14486115603331642 0.036215289033637826 5.267302816797817e-10 9.278411713371407 -0.2052769331839449 VASS(ph)PVMVSNPATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VASSPVMVSNPATR 14 0 P51610;A6NEM2;P51610-2;P51610-4 P51610 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 VAS(0.206)S(0.764)PVMVS(0.029)NPAT(0.001)R;VAS(0.072)S(0.916)PVMVS(0.013)NPATR 80.37100000000001 0.010282 56650000.0 253430.0 209986.0 299170.0 305830.0 312240.0 306690.0 322770.0 262130.0 271030.0 250240.0 True False 296330.6935293385 230832.02233087269 306303.3474085429 288695.33661423775 251058.81343359515 290606.636503111 292194.8889475645 255249.36524969345 274993.3010116161 295606.5311012492 1.0024497511113557 0.7808759213503629 1.0361859944956016 0.9766202916381292 0.8493006311406703 0.9830859806124321 0.9884588404018849 0.863476744910846 0.9302680153485079 1.0 18.17331861903351 -5.362488128616022 0.005188205619064545 1.8569474830217858 4.827278470839242e-06 0.021248740005401112 0.07776276614706937 113303.02311262232 112.02558433401875 19435.58300231356 20670.472879616613 4.340221274217991e-06 5.362488128616022 -1.856942655743315 VASS(ph)PVMVSNPATR ddPTM_PC-9_Lapatinib_30min_R1 4 VASSPVMVSNPATR 14 0 P51610;A6NEM2;P51610-2;P51610-4 P51610 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 VAS(0.218)S(0.773)PVMVS(0.009)NPATR;VAS(0.049)S(0.945)PVMVS(0.004)NPAT(0.003)R;VAS(0.192)S(0.806)PVMVS(0.002)NPATR;VAS(0.19)S(0.81)PVMVSNPATR 107.11 0.00071535 94579000.0 334770.0 286122.0 321213.0 280121.0 277745.0 306091.0 237560.0 254853.0 318750.0 240969.0 True False 329996.11841070134 285459.5020882835 294804.10705803684 300722.03279626265 261408.58516767982 293000.201462971 249859.69440999295 266694.40076661826 282849.01841369556 282620.17057899025 1.1676311628241334 1.0100464574183663 1.0431106401715275 1.0640501425648 0.9249466682867847 1.0367278487685987 0.8840830217394516 0.9436495640783684 1.000809736383063 1.0 18.108504908812925 -1.5228787883255495 0.4660332795119693 0.9605646497243611 5.62953839438074 0.5322197550571965 0.051724244146200735 73.17702086462684 0.8491568176087155 0.030651851650709543 328.33294417109767 0.02999999702654225 1.5228787883255495 4.668973744656379 VATLNS(ph)EEESDPPTYK ddPTM_PC-9_AZD4547_30min_R2 1 VATLNSEEESDPPTYK 16 0 Q00341;A0A024R4E5;Q00341-2;C9JK79;C9JIZ1;C9J5E5;C9JZI8;C9JES8;C9JHZ8;C9JHS7;C9JT62;C9JHN6;C9JEJ8;C9JBS3;C9JQ82;C9JMQ6 Q00341 HDLBP Vigilin 1 VAT(0.001)LNS(0.99)EEES(0.009)DPPTYK 170.09 3.07e-05 11522000.0 38113.0 37385.0 50466.0 60917.0 55452.0 60342.0 46275.0 73553.0 46289.0 57613.0 True False 50232.14120035243 49468.97014647913 49796.7878661014 46873.52680826806 47753.446971193756 56568.805200957 50393.38535344656 62187.07392979436 48735.74203913357 55595.98640603238 0.9035209994026124 0.8897939103947898 0.89569033819136 0.8431099048398591 0.8589369495567097 1.017498004043311 0.9064212834611867 1.1185532976360109 0.8766054024692248 1.0 15.762693114996098 -6.757525614052406 24.999336438382763 0.9863880387566218 0.8778750148292548 0.4119473574772894 0.0630492801314028 95.42201292470531 609512.0792208711 0.01988210395013997 0.019170222199135594 1.7477301808123878e-07 6.757525614052406 -0.10851302392736706 VATLNS(ph)EEESDPPTYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VATLNSEEESDPPTYK 16 0 Q00341;A0A024R4E5;Q00341-2;C9JK79;C9JIZ1;C9J5E5;C9JZI8;C9JES8;C9JHZ8;C9JHS7;C9JT62;C9JHN6;C9JEJ8;C9JBS3;C9JQ82;C9JMQ6 Q00341 HDLBP Vigilin 1 VAT(0.001)LNS(0.728)EEES(0.272)DPPTYK;VATLNS(0.847)EEES(0.153)DPPTYK 209.19 3.0743999999999996e-17 67462800.0 178588.0 214285.0 215592.0 210645.0 242295.0 179788.0 217711.0 179456.0 181786.0 162525.0 True False 208819.42112621822 235557.79863977083 220732.53091721341 198843.24357030424 194819.03407921104 170359.6007813145 197087.83798885642 174745.4701493487 184444.27634467586 191989.49595280775 1.0876606560681183 1.2269306582151371 1.1497114976095926 1.0356985551916924 1.0147379840358497 0.8873381324111086 1.0265553175747797 0.9101824518165423 0.9606998311512494 1.0 17.55066785542835 -5.975798876348293 1.8697289854170698 0.958385811104376 1.166463929584133 0.7294714896275262 0.051259407037889095 0.16033147411240686 1.1308371153818852 0.01590850061716283 0.026314732992646667 1.0573070393130291e-06 5.975798876348293 0.208078118479757 VATLNS(ph)EEESDPPTYK ddPTM_PC-9_Lapatinib_30min_R1 3 VATLNSEEESDPPTYK 16 0 Q00341;A0A024R4E5;Q00341-2;C9JK79;C9JIZ1;C9J5E5;C9JZI8;C9JES8;C9JHZ8;C9JHS7;C9JT62;C9JHN6;C9JEJ8;C9JBS3;C9JQ82;C9JMQ6 Q00341 HDLBP Vigilin 1 VATLNS(0.956)EEES(0.043)DPPTYK;VAT(0.025)LNS(0.96)EEES(0.015)DPPTYK;VAT(0.013)LNS(0.932)EEES(0.055)DPPTYK 279.19 1.2018999999999997e-82 28201200.0 120809.0 176759.0 181254.0 163211.0 180604.0 192084.0 167794.0 171638.0 193305.0 169362.0 True False 119086.24150634251 176349.7253955405 166351.99578067346 175214.08139593527 169981.2278011254 183869.01508967392 176481.55229765247 179612.9280753252 171532.95530810818 198635.99603932028 0.5995199454320919 0.8878034641849699 0.83747155146917 0.8820862526913369 0.8557423185648455 0.9256580818980905 0.8884671248745756 0.9042315172309986 0.863554233514418 1.0 17.59976756055456 -4.761417919812476 10.925772179112334 0.8884415981397628 0.59880444551024 0.8085204410919338 0.04290295033377108 0.026200120154889508 101.67057054302123 0.009932738746681474 0.055866660791206856 1.732136367728688e-05 4.761417919812476 -0.2896371526295227 VATLNS(ph)EEESDPPTYKDAFPPLPEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VATLNSEEESDPPTYKDAFPPLPEK 25 1 Q00341;A0A024R4E5;Q00341-2;C9JK79;C9JIZ1;C9J5E5;C9JZI8;C9JES8;C9JHZ8;C9JHS7;C9JT62;C9JHN6;C9JEJ8;C9JBS3;C9JQ82 Q00341 HDLBP Vigilin 1 VAT(0.027)LNS(0.505)EEES(0.444)DPPT(0.018)Y(0.005)KDAFPPLPEK 59.56100000000001 0.0017513 11320000.0 31820.0 12721.0 23595.0 52248.0 52138.0 63640.0 45752.0 73436.0 54587.0 37874.0 True False 37206.497526352636 13983.85680983983 24157.5942845358 49320.713950301484 41921.933175764665 60302.606368182875 41418.03934420466 71508.38281187361 55385.23160654192 44740.25638958095 0.8316111826086279 0.3125564746002746 0.5399520752447361 1.10237888493163 0.9370069945671431 1.3478377469071916 0.9257443449485917 1.5983006934338084 1.2379283463257031 1.0 15.4492859035128 -5.801763992361309 3.8558854787920516 1.1869382212384112 0.5282287835020159 0.6022529499641347 0.2243390765512892 0.13905912430207734 4.330486846668275 0.06384805547968085 0.10374053464485944 1.5784688203041443e-06 5.801763992361309 -0.6587094377363953 VATLNSEEES(ph)DPPTYK ddPTM_PC-9_AZD4547_30min_R2 5 VATLNSEEESDPPTYK 16 0 Q00341;A0A024R4E5;Q00341-2;C9JK79;C9JIZ1;C9J5E5;C9JZI8;C9JES8;C9JHZ8;C9JHS7;C9JT62;C9JHN6;C9JEJ8;C9JBS3;C9JQ82;C9JMQ6 Q00341 HDLBP Vigilin 1 VATLNS(0.075)EEES(0.925)DPPTYK;VATLNS(0.039)EEES(0.96)DPPTYK;VATLNS(0.195)EEES(0.805)DPPTYK;VATLNSEEES(1)DPPTYK;VATLNS(0.007)EEES(0.993)DPPTYK 174.24 1.3147e-05 311049700.0 279257.0 288237.0 341698.0 362836.0 359970.0 370998.0 350081.0 422659.0 371177.0 357718.0 True False 368054.91709355963 381403.97346825444 337166.861258493 279189.76596031897 309994.37903449195 347799.4364115311 381237.5308032404 357346.76328760176 390796.65844713594 345194.4017008844 1.0662250467563612 1.1048961732547045 0.9767448707081079 0.8087899588888485 0.8980284080710738 1.0075465728812834 1.1044140024425653 1.035204399395931 1.132106014818185 1.0 18.39704954178142 -7.034237838232566 6.815277373403348 1.0692624255468315 0.9679981002448165 0.23010883512911584 0.08358474925063401 0.3519826708333566 52.78530023392001 0.03570207242920974 0.02830086388981306 9.241919083089042e-08 7.034237838232566 -0.10126432530201501 VATLNSEEES(ph)DPPTYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 VATLNSEEESDPPTYK 16 0 Q00341;A0A024R4E5;Q00341-2;C9JK79;C9JIZ1;C9J5E5;C9JZI8;C9JES8;C9JHZ8;C9JHS7;C9JT62;C9JHN6;C9JEJ8;C9JBS3;C9JQ82;C9JMQ6 Q00341 HDLBP Vigilin 1 VATLNS(0.006)EEES(0.994)DPPTYK;VATLNSEEES(0.996)DPPT(0.004)YK;VATLNS(0.125)EEES(0.875)DPPTYK;VATLNS(0.23)EEES(0.77)DPPTYK;VATLNS(0.111)EEES(0.889)DPPTYK 251.04 1.3294999999999999e-47 127210800.0 235382.3 306261.0 286355.0 293190.0 311688.0 237644.0 279937.0 242352.0 240118.0 213686.0 True False 275227.8743776617 336664.5680715628 293182.78920738434 276763.51483480464 250614.9738710293 225181.5302916474 253419.34079162922 235990.51679316966 243629.27149137369 252425.58026255528 1.0903327392231368 1.3337181109829996 1.1614622769310317 1.096416276618775 0.9928271675570965 0.8920709622908639 1.0039368455765867 0.9348914501759646 0.9651528630258777 1.0 17.94549859176186 -6.021724086618965 1.896723216938707 0.9570216268569653 1.2147983746397744 0.7307161575454955 0.0635333162841923 0.1579023704128542 1.1383718688755489 0.01983528555220715 0.03141702458682582 9.512089181104567e-07 6.021724086618965 0.257776747782809 VATLNSEEES(ph)DPPTYK ddPTM_PC-9_Lapatinib_30min_R1 4 VATLNSEEESDPPTYK 16 0 Q00341;A0A024R4E5;Q00341-2;C9JK79;C9JIZ1;C9J5E5;C9JZI8;C9JES8;C9JHZ8;C9JHS7;C9JT62;C9JHN6;C9JEJ8;C9JBS3;C9JQ82;C9JMQ6 Q00341 HDLBP Vigilin 1 VATLNSEEES(1)DPPTYK;VAT(0.002)LNS(0.42)EEES(0.578)DPPTYK;VATLNS(0.116)EEES(0.874)DPPT(0.009)YK;VATLNS(0.022)EEES(0.978)DPPTYK 192.46 9.9569e-39 290540000.0 152891.0 199580.0 219055.0 196309.0 220661.0 222951.0 206088.0 233329.0 218716.0 192234.0 True False 150710.74630322485 199117.88477215852 201045.1434767535 210746.2187276269 207682.15381621764 213415.9054541655 216758.2282436715 244170.3171493926 194081.9008984156 225461.3907642962 0.6684547886107124 0.8831573516741146 0.8917054170349363 0.9347330734242966 0.9211428755592771 0.9465740663210785 0.961398435044148 1.0829806217449232 0.8608210046096734 1.0 17.782520874117417 -4.0421543182930915 0.8368081410390606 0.9645991163153371 1.1367408866571464e-27 0.7019141407444879 0.05575759188082962 3.91373790595958 0.8682134987831757 0.019139937808585628 4.676399895039704 9.074980107042207e-05 4.0421543182930915 -0.9645991163153371 VATTPGS(ph)PSLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VATTPGSPSLGR 12 0 A0A087WWW7;E9PGF5;E9PF55;A0A494C067;A0A2R8Y4T1;Q9HBL0;H0Y4U1 A0A087WWW7 TNS1 Tensin-1 1 VAT(0.001)T(0.02)PGS(0.976)PS(0.002)LGR;VATT(0.002)PGS(0.706)PS(0.292)LGR 128.21 0.00021137 12375300.0 72608.0 72624.0 64517.0 75790.0 95213.0 47151.0 72000.0 67210.0 60202.0 45186.0 True False 84899.10032663157 79833.63076470475 66055.32996208503 71543.7320144953 76556.6961422396 44678.3185554084 65179.63876514121 65445.80871488134 61082.34035900558 53377.86410782078 1.5905301147895197 1.4956317960464767 1.237504180172072 1.3403258674790792 1.43424053063642 0.8370196017053116 1.221098668044892 1.226085191095018 1.1443384140590962 1.0 15.70395395736531 -1.5228787678023574 0.2848087171672814 1.0699048728091005 5.297007214995118 0.5608496323643881 0.14276314744287505 41.26032058285551 0.58363713871136 0.15898857432133132 87.29561653439613 0.029999998444234025 1.5228787678023574 4.227102342186018 VATTPGS(ph)PSLGR ddPTM_PC-9_Lapatinib_30min_R1 1 VATTPGSPSLGR 12 0 A0A087WWW7;E9PGF5;E9PF55;A0A494C067;A0A2R8Y4T1;Q9HBL0;H0Y4U1 A0A087WWW7 TNS1 Tensin-1 1 VATT(0.01)PGS(0.495)PS(0.495)LGR 120.59 0.00048587 9544600.0 46884.0 60820.0 59974.0 53455.0 61320.0 42393.0 39401.0 42582.0 49924.0 36441.0 True False 46215.42556252739 60679.175026769655 55043.16922633488 57386.25902065256 57713.27815975846 40579.95021290968 41440.99098942635 44560.515173233674 44301.03339697368 42739.778295419674 1.0813211346835692 1.4197353717502206 1.2878674485832262 1.3426896748035428 1.3503410747908222 0.9494656226903859 0.9696117444265612 1.0426005222869656 1.0365293214850702 1.0 15.383291803856762 -6.76075989130577 24.999998998523353 1.0004270925154832 1.3053420610975905 0.7490381803702931 0.08580512492612999 8.681367582148361 319412.2933384804 0.028267978501381033 0.0266824667714512 1.734762832215412e-07 6.76075989130577 0.3049149685821073 VAVAT(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 2 VAVATPAK 8 0 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 1 VAVAT(1)PAK;VAVAT(1)PAK 96.665 0.014793 84421000.0 443813.0 508550.0 632750.0 756930.0 802500.0 699650.0 604120.0 805960.0 707250.0 798950.0 True False 584936.302116128 672928.8422627244 624359.3215684947 582431.4829519232 691086.727158317 655900.7748972465 657885.5096644884 681417.4011183367 744633.7911205088 770979.0036814526 0.7586929077485068 0.8728238240593647 0.8098266212012991 0.7554440265828145 0.896375548307221 0.850737532105669 0.8533118366687825 0.8838339278560687 0.9658288845284444 1.0 19.556332045735218 -8.078124683998594 0.5799075439666809 1.00714680590612 0.8093549715034526 0.7065364292174127 0.04071171341798999 0.43624972708179854 0.3401166218983261 0.04078577786683182 0.021047371617985852 8.353631547846504e-09 8.078124683998594 -0.19779183440266734 VAVAT(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VAVATPAK 8 0 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 1 VAVAT(1)PAK 92.23899999999999 0.019864 29191000.0 143310.0 164830.0 167420.0 164470.0 188180.0 162960.0 155240.0 140320.0 119450.0 112660.0 True False 167569.5524984789 181193.2330764799 171411.927743886 155255.27911893427 151307.47986143327 154414.09072531568 140534.5433597295 136636.7486813295 121196.73027280175 133084.36618393095 1.2591227452433238 1.3614914980025488 1.2879944704172386 1.1665929182422654 1.1369290338154132 1.1602722029115404 1.0559808592806605 1.0266927107913557 0.9106759399920819 1.0 17.02198157796571 -6.634528995162634 0.5521790594454509 0.9558533947534902 1.3411366514003689 0.8727828336838042 0.04761962548360513 0.3224131816098243 0.212192851493842 0.041044856330219606 0.056524521159268926 2.3199092943711226e-07 6.634528995162634 0.3852832566468787 VAVAT(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 1 VAVATPAK 8 0 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 1 VAVAT(1)PAK 89.88600000000001 0.02418 43533000.0 399950.0 420560.0 434170.0 422960.0 402450.0 337870.0 340070.0 316730.0 385640.0 286880.0 True False 394246.63965815306 419586.21915913024 398474.2185446655 454065.8893531993 378778.6822471432 323420.08771343867 357677.1606247105 331446.43207971175 342205.1622307692 336466.82575642865 1.1717251433980946 1.2470359246140732 1.184289766602799 1.3495116148000328 1.1257534272378593 0.9612242959951284 1.0630384134322834 0.9850790827136366 1.0170546872234427 1.0 18.360104742493732 -6.53578621915397 5.218911729630141 1.0098814943881917 1.2359867318066473 0.8226128077559206 0.05096082740330616 0.06864367569069686 5.600836618384904 0.016075168884729926 0.01668746801974819 2.9121502671655096e-07 6.53578621915397 0.22610523741845556 VAVEEVDEEGKFVR ddPTM_PC-9_AZD4547_30min_R2 2 VAVEEVDEEGKFVR 14 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ; 120.59 0.00010954 18055500.0 57446.0 34642.0 61984.0 80175.0 80732.0 68299.0 55225.0 60225.0 49441.0 63391.0 False True 75712.63304897133 45839.34903876767 61162.051660373836 61691.89244140205 69523.75533575723 64028.25273309073 60139.91801499912 50918.61008282276 52054.350324198014 61171.70038471876 1.2377068574651724 0.7493554821997191 0.9998422681683812 1.0085038024676725 1.136534621377386 1.0466972853526493 0.9831330114541432 0.8323883390945053 0.8509547715172171 1.0 15.900576758657749 -7.61145230833155 5.430896228677816 0.8824844695268511 1.0192256194520983 0.18796954689633116 0.12369286572730706 0.3451423588047987 16.41874124834629 0.05917562980935866 0.03347678553917512 2.4465139230857423e-08 7.61145230833155 0.13674114992524722 VAVEEVDEEGKFVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VAVEEVDEEGKFVR 14 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ;; 168.76 3.2336e-05 18679900.0 61502.3 47683.2 52276.0 72944.4 76946.7 86496.5 73263.0 82595.2 66512.9 59911.6 False True 71913.42466420474 52416.872968709555 53522.458097834 68857.56175693555 61869.5465015077 81960.4712716143 66322.99826181296 80427.16351684822 67485.52533245558 70773.09882003535 1.0161124193115953 0.7406327240523587 0.7562542687855599 0.9729341078031541 0.8741958107392195 1.158073796938391 0.9371215810468003 1.136408675863715 0.9535476961954211 1.0 16.110913469039048 -6.348159807128439 1.774763885363032 1.0357537537289723 0.8397333440770542 0.34214553121967206 0.10653665860946819 0.3612009903050479 2.251763151568306 0.03702806818133195 0.045978385028860785 4.4858029568780946e-07 6.348159807128439 -0.19602040965191803 VAVEEVDEEGKFVR ddPTM_PC-9_Lapatinib_30min_R1 2 VAVEEVDEEGKFVR 14 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 ; 147.96 0.00023921 28806000.0 81133.0 66196.0 72003.0 67321.0 76875.0 67985.0 64881.0 59133.0 74364.0 59249.0 False True 79976.02854202996 66042.72722907003 66083.19127961782 72272.0109162726 72353.36364206519 65077.440030775506 68240.22071482895 61880.535055629756 65988.34323236422 69490.11070567001 1.1508979872081908 0.9503903009853935 0.9509726003965885 1.0400330375409172 1.0412037469406643 0.9364992999711187 0.9820134120071407 0.8904941210660734 0.949607686075825 1.0 16.084520058809467 -6.767243437425522 24.963559949334854 0.9467719333754759 1.0189938327955606 0.28020522696342964 0.0591810116441715 198.4003570896402 853325.1161262998 0.020595877565214957 0.018647482274058446 1.7090570595868737e-07 6.767243437425522 0.07222189942008461 VAVEYLDPS(ph)PEVQK ddPTM_PC-9_AZD4547_30min_R2 1 VAVEYLDPSPEVQK 14 0 J3QT28;O43684-2;O43684 J3QT28 BUB3 Mitotic checkpoint protein BUB3 1 VAVEYLDPS(1)PEVQK 116.79 0.0017428 0.0 15727.0 10545.0 13029.0 23755.0 16210.0 17273.0 12584.0 14898.0 10815.0 11681.0 True False 20727.85885807841 13953.465031285868 12856.226947002637 18278.651761091438 13959.521304967371 16192.916579432725 13703.951621561786 12595.856421982451 11386.65882073991 11272.051745419689 1.8388718687794363 1.2378815628623911 1.1405400930870164 1.6215904765091969 1.2384188451441163 1.4365544929309424 1.2157459822813785 1.117441323590506 1.0101673659692691 1.0 13.460462519152879 -7.664569055393557 1.1955872264272436 0.9904568639346216 1.4100450286514175 0.44663781402497904 0.19080558338971595 0.48492056152505997 1.2726978320308837 0.1541492715314897 0.06415339866984925 2.164865625489444e-08 7.664569055393557 0.41958816471679583 VAVNALAVGEPGT(ph)ASKPASPIGGPTQEEK ddPTM_PC-9_AZD4547_30min_R2 1 VAVNALAVGEPGTASKPASPIGGPTQEEK 29 1 Q96L91-5;Q96L91-2;Q96L91;Q96L91-4;Q96L91-3 Q96L91-5 EP400 E1A-binding protein p400 1 VAVNALAVGEPGT(0.495)AS(0.29)KPAS(0.206)PIGGPT(0.01)QEEK 58.858000000000004 0.0011195 10450000.0 34510.0 35061.0 38693.0 66895.0 51806.0 49004.0 43287.0 44779.0 40222.0 48614.0 True False 45483.46214740801 46393.7825947761 38179.905538442916 51473.39126744733 44613.63113665268 45939.77213330175 47139.45914196953 37859.43446905305 42348.05280515955 46912.03865695 0.9695477632087443 0.9889525998653841 0.8138615722424286 1.0972320270251477 0.9510060192202539 0.9792746904316381 1.0048478064806046 0.8070302539163727 0.9027118415133234 1.0 15.517670576958997 -10.380965204300596 4.46567456215127 1.0000003734366554 0.9466352556655385 0.03678105178909208 0.08277435555301416 115499485.02201347 201820158.04203066 724.5715611073132 0.020723938013085686 4.1594393461151626e-11 10.380965204300596 -0.053365117771116855 VAVNALAVGEPGT(ph)ASKPASPIGGPTQEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VAVNALAVGEPGTASKPASPIGGPTQEEK 29 1 Q96L91-5;Q96L91-2;Q96L91;Q96L91-4;Q96L91-3 Q96L91-5 EP400 E1A-binding protein p400 1 VAVNALAVGEPGT(0.365)AS(0.365)KPAS(0.256)PIGGPT(0.015)QEEK 73.058 2.1065e-05 5498100.0 19423.0 17774.0 17610.0 26097.0 34139.0 26956.0 27984.0 28412.0 29109.0 24083.0 True False 22710.930278263568 19538.485255726206 18029.889186296892 24634.869697615544 27449.708018862042 25542.379906674054 25333.152933384863 27666.21510500238 29534.664056182384 28449.05725907691 0.7983016825985492 0.6867884962863677 0.6337605152291753 0.8659292107036546 0.9648723249029274 0.8978286933752275 0.8904742502601596 0.9724826679863088 1.038159675634211 1.0 14.796093225044768 -5.942576164643038 4.409893900336538 0.950439308885481 0.705687232773942 0.8011621354993184 0.05643414849086925 0.09391002918278563 3.774063451184434 0.017162131478333925 0.025750941673494232 1.1413631198559701e-06 5.942576164643038 -0.24475207611153904 VAVNALAVGEPGTASKPAS(ph)PIGGPTQEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VAVNALAVGEPGTASKPASPIGGPTQEEK 29 1 Q96L91-5;Q96L91-2;Q96L91;Q96L91-4;Q96L91-3 Q96L91-5 EP400 E1A-binding protein p400 1 VAVNALAVGEPGT(0.072)AS(0.016)KPAS(0.724)PIGGPT(0.188)QEEK;VAVNALAVGEPGT(0.238)AS(0.238)KPAS(0.349)PIGGPT(0.174)QEEK 61.228 0.00045310000000000006 10536500.0 23565.4 27728.2 19757.8 36591.0 39381.0 35193.0 41103.0 33879.0 29670.0 26416.4 True False 27554.5567821342 30480.872446710237 20228.900883873768 34540.92489962261 31664.575748873922 33347.4171262643 37209.42628004994 32989.71214776769 30103.867619874673 31205.48420789265 0.8830036604644309 0.9767793456959357 0.6482482613987888 1.1068863623300658 1.0147118864723514 1.068639630909169 1.1924002214533413 1.0571767426516576 0.9646979812689671 1.0 14.929511977362566 -5.794746760094251 24.993499632865763 1.0644361993013862 0.8500869349891379 0.5248408199236927 0.0962771498042382 142.48646027303198 106919.73394807307 0.02695263661196123 0.03997994357080845 1.6041805260045264e-06 5.794746760094251 -0.21434926431224832 VAVNDAHLLQYNHR ddPTM_PC-9_AZD4547_30min_R2 2 VAVNDAHLLQYNHR 14 0 P17931 P17931 LGALS3 Galectin-3 0 ; 196.7 4.5441e-08 22569400.0 88508.0 80344.0 128694.0 166616.0 155698.0 127450.0 116525.0 149814.0 101974.0 122635.0 False True 116651.70291923494 106313.62678744734 126987.43347283405 128205.25539153923 134082.02024310967 119480.53135232437 126895.49926116384 126663.68868323785 107364.13745595292 118341.58597718918 0.9857202939778078 0.8983623627280077 1.0730584048223875 1.0833491399739337 1.1330084782618557 1.0096242192947686 1.0722815501697218 1.0703227241491657 0.9072392985898279 1.0 16.852597609317904 -5.268363558875222 24.78639282176676 1.050544200571339 0.9420413265435169 0.29882357139258797 0.06150469697624785 486.27999273079547 1740735.3261817088 0.015941334107436613 0.034405300639131706 5.390591735382912e-06 5.268363558875222 -0.1085028740278221 VAVNDAHLLQYNHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VAVNDAHLLQYNHR 14 0 P17931 P17931 LGALS3 Galectin-3 0 80.17 0.0050108 4057600.0 14024.0 14558.0 20610.0 16539.0 19674.0 17848.0 15346.0 16069.0 16327.0 18401.0 False True 16397.986213374275 16003.222029529776 21101.42056386027 15612.373450161462 15819.020930990717 16912.0194603917 13892.315784581324 15647.205776512856 16565.751487350655 21736.955637764157 0.7543828347740492 0.7362218654817962 0.9707624616577053 0.7182410320163554 0.7277477671945899 0.778030729887953 0.6391104631251056 0.7198434793384118 0.762100809488269 1.0 14.407862277879158 -10.390595712537579 2.7863168006480197 1.0001444265256798 0.7561552515889784 0.45424710971091453 0.0801455611346132 312656.0455464695 464540.16076239286 549.0203832067673 0.02151312510214755 4.068218659783395e-11 10.390595712537579 -0.24398917493670136 VAVNDAHLLQYNHR ddPTM_PC-9_Lapatinib_30min_R1 2 VAVNDAHLLQYNHR 14 0 P17931 P17931 LGALS3 Galectin-3 0 ; 203.61 5.037699999999999e-11 14267200.0 95738.0 92699.0 106973.0 87654.0 83437.0 87562.0 78920.0 77018.0 103137.0 67140.0 False True 94372.75856380112 92484.36116090954 98178.0928677215 94100.36756517235 78529.39970345353 83817.17737699147 83006.09144147424 80596.53744803234 91520.62497924182 78745.05954157347 1.1984594222571767 1.1744782682154478 1.2467841594035287 1.19500027192807 0.9972612905574593 1.0644118864719403 1.0541117363388512 1.0235123056257438 1.1622395806421797 1.0 16.264901791322906 -6.221245898780075 10.009088561443177 1.052355133953531 1.204827482639539 0.7228506151643691 0.04652813166173284 0.3301736224378463 80.77297522178719 0.013287449371927763 0.017109602824859193 6.008334475361828e-07 6.221245898780075 0.152472348686008 VAVPT(ph)GPTPLDSTPPGGAPHPLTGQEEAR ddPTM_PC-9_Lapatinib_30min_R1 1 VAVPTGPTPLDSTPPGGAPHPLTGQEEAR 29 0 A0A0A0MR08;O94966-2;O94966-7;O94966-6;O94966-5;E7ESU0;O94966-4;O94966-3;O94966 A0A0A0MR08 USP19 Ubiquitin carboxyl-terminal hydrolase 19;Ubiquitin carboxyl-terminal hydrolase 1 VAVPT(0.449)GPT(0.082)PLDS(0.21)T(0.259)PPGGAPHPLTGQEEAR 92.38 2.0406e-08 7720600.0 24778.0 17051.0 25726.0 18559.0 19357.0 23886.0 23206.0 20636.0 25540.0 10282.0 True False 24424.6611762713 17011.519457110324 23610.907585231776 19923.890771009093 18218.45931732623 22864.451460985547 24407.49313216995 21594.823895421785 22663.41625187701 12059.230000096197 2.0253914367730332 1.4106638199101122 1.9579117062236504 1.6521693981166425 1.5107481420605544 1.8960125531068863 2.0239677932981834 1.7907299135392163 1.8793419025672637 1.0 13.55785017148832 -6.8439964682005785 22.561306080487874 1.7865480501746944 1.7048040834326308 0.0 0.31455180444393116 79.52165627319413 21715.45478127534 0.10411523365535756 0.09182109270392505 1.4321995462577264e-07 6.8439964682005785 -0.08174396674206363 VAVPTGPTPLDS(ph)TPPGGAPHPLTGQEEAR ddPTM_PC-9_AZD4547_30min_R2 1 VAVPTGPTPLDSTPPGGAPHPLTGQEEAR 29 0 A0A0A0MR08;O94966-2;O94966-7;O94966-6;O94966-5;E7ESU0;O94966-4;O94966-3;O94966 A0A0A0MR08 USP19 Ubiquitin carboxyl-terminal hydrolase 19;Ubiquitin carboxyl-terminal hydrolase 1 VAVPT(0.002)GPTPLDS(0.557)T(0.441)PPGGAPHPLTGQEEAR 96.382 7.3939e-11 9283800.0 18313.0 15520.0 26752.0 30860.0 26131.0 20143.0 18836.0 28441.0 20910.0 22982.0 True False 24136.153065936916 20536.53648985839 26397.25100055373 23745.70378224719 22503.16170389281 18883.455025734573 20512.367509832944 24046.09695916251 22015.259911388952 22177.407175176384 1.0883216813980399 0.9260116084645524 1.1902766988063735 1.070715958573653 1.0146885759071533 0.8514726215096597 0.9249218065848945 1.0842609674442822 0.9926886284538742 1.0 14.436803085257736 -6.521611622169199 24.99712775548532 0.9686320057521454 1.064229428605382 0.24354006880683854 0.0813536868332168 75.85660981919328 1496500.4713303566 0.027911285785955153 0.028268896680427674 3.0087657578869704e-07 6.521611622169199 0.09559742285323658 VAVPTGPTPLDS(ph)TPPGGAPHPLTGQEEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VAVPTGPTPLDSTPPGGAPHPLTGQEEAR 29 0 A0A0A0MR08;O94966-2;O94966-7;O94966-6;O94966-5;E7ESU0;O94966-4;O94966-3;O94966 A0A0A0MR08 USP19 Ubiquitin carboxyl-terminal hydrolase 19;Ubiquitin carboxyl-terminal hydrolase 1 VAVPT(0.024)GPT(0.169)PLDS(0.468)T(0.338)PPGGAPHPLTGQEEAR 58.191 0.00097471 7319700.0 22310.0 31951.0 35434.0 35179.0 28379.0 31526.0 34254.0 36275.0 24092.0 19101.0 True False 26086.64235741442 35122.88412319728 36278.880944193326 33208.034681856836 22818.33867035606 29872.721061648845 31009.21314251589 35322.819686539544 24444.299922413902 22563.860096567205 1.1561249824174882 1.5565990913292695 1.6078313191506042 1.4717355337134448 1.0112781488938398 1.323918909876311 1.3742867137894343 1.5654599671938867 1.083338569632985 1.0 14.461726276443791 -12.831504616124146 0.19007518834411835 0.2058450303337278 1.4459705004758434 0.25384408355309374 0.19419079237963918 97.61883520836545 1.6996750219844219 30.882926242275435 0.5859745365484095 1.473992873792808e-13 12.831504616124146 1.2401254701421156 VAVPTGPTPLDS(ph)TPPGGAPHPLTGQEEAR ddPTM_PC-9_Lapatinib_30min_R1 1 VAVPTGPTPLDSTPPGGAPHPLTGQEEAR 29 0 A0A0A0MR08;O94966-2;O94966-7;O94966-6;O94966-5;E7ESU0;O94966-4;O94966-3;O94966 A0A0A0MR08 USP19 Ubiquitin carboxyl-terminal hydrolase 19;Ubiquitin carboxyl-terminal hydrolase 1 VAVPT(0.104)GPT(0.254)PLDS(0.348)T(0.295)PPGGAPHPLTGQEEAR 86.32 2.7810000000000002e-08 9013400.0 40210.0 38290.0 46312.0 35424.0 34004.0 39214.0 35230.0 33160.0 50921.0 27299.0 True False 39636.59802638908 38201.341857530584 42504.406129489806 38029.19913099984 32003.95157443618 37536.90863229876 37054.03701828612 34700.73465653159 45185.740758098196 32017.595776368977 1.237962972086849 1.1931358658018165 1.3275327237674968 1.1877593619652045 0.9995738530141959 1.172383738444327 1.157302293310679 1.0838020099605024 1.411278381853023 1.0 14.966577358492478 -5.995805605447744 24.619464427178265 1.1397200945496306 1.2486935781289006 0.17399894780358494 0.11261743779744188 183.8489470223327 1079094.5717126147 0.030823392845661903 0.04549350121023441 1.0097047388785596e-06 5.995805605447744 0.10897348357926995 VAVPTGPTPLDST(ph)PPGGAPHPLTGQEEAR ddPTM_PC-9_AZD4547_30min_R2 1 VAVPTGPTPLDSTPPGGAPHPLTGQEEAR 29 0 A0A0A0MR08;O94966-2;O94966-7;O94966-6;O94966-5;E7ESU0;O94966-4;O94966-3;O94966 A0A0A0MR08 USP19 Ubiquitin carboxyl-terminal hydrolase 19;Ubiquitin carboxyl-terminal hydrolase 1 VAVPT(0.004)GPT(0.004)PLDS(0.132)T(0.86)PPGGAPHPLTGQEEAR 68.619 0.00028533 10018000.0 17559.0 19698.0 23811.0 29939.0 27940.0 28024.0 23193.0 24321.0 24223.0 26451.0 True False 23142.39675011121 26064.99328461537 23495.250582168974 23037.026102939028 24061.013279505754 26271.654849882634 25257.132069205545 20562.74829098102 25503.37832776538 25524.958541057793 0.9066575647081209 1.021157125199201 0.9204814395438111 0.902529422952173 0.9426465175566404 1.0292535757746188 0.9895072710335087 0.8055937978471196 0.9991545446290264 1.0 14.63962099735541 -4.485804539592798 18.250754485230363 0.9514353274403202 0.6940074094980273 0.04586292655619739 0.06457465329313661 19401420.51967395 251324547.81924343 0.01611213032221896 168818470.22061527 3.267348507516688e-05 4.485804539592798 -0.2574279179422929 VAVPTGPTPLDST(ph)PPGGAPHPLTGQEEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VAVPTGPTPLDSTPPGGAPHPLTGQEEAR 29 0 A0A0A0MR08;O94966-2;O94966-7;O94966-6;O94966-5;E7ESU0;O94966-4;O94966-3;O94966 A0A0A0MR08 USP19 Ubiquitin carboxyl-terminal hydrolase 19;Ubiquitin carboxyl-terminal hydrolase 1 VAVPT(0.115)GPT(0.033)PLDS(0.219)T(0.634)PPGGAPHPLTGQEEAR 50.493 0.026952999999999998 6707000.0 10540.0 12206.0 13369.0 13218.0 14851.0 10098.0 12572.0 11572.0 10779.0 8492.1 True False 12324.213825510898 13417.731013356251 13687.767662214834 12477.438313334189 11941.053158795523 9568.443103486967 11381.08914660215 11268.247261547504 10936.622483135461 10031.650506573384 1.2285330133296888 1.3375397203644694 1.3644581869399983 1.2438071187944764 1.1903378363282269 0.9538254046248029 1.1345181073786936 1.1232695212182504 1.0902116731408338 1.0 13.292271371516508 -6.370593880623645 2.544202846802143 1.0731281550044138 1.3073430870260327 0.7378579000808612 0.06486410108667152 0.15027412493027142 1.8989247926551762 0.021899723697115403 0.02576496866056172 4.2599658674573583e-07 6.370593880623645 0.23421493202161892 VAVTEGCQPSR ddPTM_PC-9_Lapatinib_30min_R1 1 VAVTEGCQPSR 11 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 93.667 0.027552999999999998 0.0 17004.0 18672.0 18862.0 15771.0 17649.0 19688.0 22592.0 14755.0 18352.0 18220.0 False True 16761.519841848294 18628.76613120427 17311.239169425553 16930.851950513734 16610.92051926905 18845.9901349696 23761.70321649503 15440.571165775758 16285.004504872608 21369.302723376055 0.7843737373570328 0.8717535790639585 0.8100984572832434 0.7922978194320275 0.7773262765891855 0.8819188149903374 1.111955009673849 0.7225584926964038 0.7620746786023256 1.0 14.383252213427406 -6.84052101194462 7.399231836375578 0.8925987876286295 0.8102507348267483 0.14920849492335742 0.10560144015531929 0.5481370684184341 43.50181919280627 0.03894396617890852 0.0344061852498767 1.4437067534833672e-07 6.84052101194462 -0.08234805280188129 VCAKPWAPDMTLPGIS(ph)PPPEK ddPTM_PC-9_AZD4547_30min_R2 1 VCAKPWAPDMTLPGISPPPEK 21 1 Q96FF9;B5MBX0 Q96FF9 CDCA5 Sororin 1 VCAKPWAPDMTLPGIS(1)PPPEK 89.01100000000001 0.00065815 7501200.0 58012.0 42245.0 57242.0 79992.0 64179.0 55792.0 51880.0 63024.0 57065.0 54956.0 True False 76458.6092754399 55899.87010399918 56482.93367874163 61551.08026408024 55268.85366017895 52303.3174202345 56497.21949512277 53285.088947444085 60081.339399493554 53032.00716730451 1.4417445870798276 1.0540779632882304 1.0650725231000628 1.1606402161981142 1.0421791784312004 0.9862594348961534 1.065341904123792 1.00477224592577 1.132925993352466 1.0 15.694575732507019 -4.761078212900593 24.99413859976103 1.0580647839976656 1.4417450181629223 0.8271562789927078 0.052786226637019804 3.3843681876875644 233895.8147807189 0.013157669052397892 0.0748951394233406 1.7334917818836798e-05 4.761078212900593 0.38368023416525676 VCAKPWAPDMTLPGIS(ph)PPPEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VCAKPWAPDMTLPGISPPPEK 21 1 Q96FF9;B5MBX0 Q96FF9 CDCA5 Sororin 1 VCAKPWAPDMT(0.002)LPGIS(0.998)PPPEK 54.74 0.02779 6875100.0 31082.0 24550.0 33826.0 33316.0 43008.0 31104.0 39730.0 37032.0 25650.0 28788.0 True False 36343.568702517055 26987.16175470228 34632.54012581935 31449.412531929353 34580.89113551124 29472.85148453738 35966.48677970914 36059.949238647314 26025.08272496748 34007.03651431739 1.0687073155350058 0.7935758160914829 1.018393358422708 0.9247913301321846 1.016874584792246 0.8666692104185243 1.0576189655504618 1.060367292617974 0.7652852289557954 1.0 15.053545669853388 VCAKPWAPDMTLPGIS(ph)PPPEK ddPTM_PC-9_Lapatinib_30min_R1 1 VCAKPWAPDMTLPGISPPPEK 21 1 Q96FF9;B5MBX0 Q96FF9 CDCA5 Sororin 1 VCAKPWAPDMTLPGIS(1)PPPEK 88.264 0.00066674 3412800.0 15989.0 11460.0 16415.0 12819.0 12717.0 11957.0 12104.0 9607.3 14541.0 14419.0 True False 15760.993927976511 11433.465074100302 15065.422063732402 13761.75202293042 11969.01106258397 11445.626983128377 12730.685894673152 10053.690231172977 12903.239456481724 16911.304937890203 0.9319797606312218 0.6760841411169481 0.8908491756882667 0.8137605036082619 0.7077520691952695 0.6768032996368105 0.7527914576331558 0.5944952366536441 0.7629949021598973 1.0 14.045700367197156 -4.745518525784885 24.528649535679257 0.7519701341604701 0.9319804009483509 0.16404969151438542 0.11086424381862356 1233.1917428483282 1899798.789798464 0.02676948198670149 0.6580827490786271 1.7967244353121832e-05 4.745518525784885 0.1800102667878808 VCEEIAIIPSK ddPTM_PC-9_Lapatinib_30min_R1 1 VCEEIAIIPSK 11 0 H3BNC9;P08708;H0YN88;A0A075B716;H0YN73 H3BNC9 RPS17 40S ribosomal protein S17 0 133.81 0.0006204 0.0 53605.0 46741.0 53222.0 45332.0 48766.0 44880.0 50460.0 44193.0 43448.0 45882.0 False True 52840.58287004695 46632.77408625846 48846.29260286118 48665.866503118945 45897.67975764488 42960.587020389845 53072.571897323796 46246.36811447834 38554.4287122769 53812.64256607791 0.9819362207526354 0.8665765489772573 0.9077103497171983 0.9043574926349489 0.8529162956694787 0.7983363197159004 0.9862472713945358 0.8593959692221256 0.7164567074537352 1.0 15.715657534202506 -2.434530852962445 1.4646121939893373 0.8725384597730033 124.21855557709225 0.13010169634728597 0.07894690961843606 3176.355615817389 7.9041634099986 0.021746585465255555 1315642.601360923 0.003676792719371217 2.434530852962445 123.34601711731925 VCEEIAIIPSKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VCEEIAIIPSKK 12 1 H3BNC9;P08708;H0YN88;A0A075B716;H0YN73 H3BNC9 RPS17 40S ribosomal protein S17 0 72.49600000000001 0.015750999999999998 3900900.0 29809.0 23087.0 29470.0 26501.0 29752.0 29080.0 28971.0 36302.0 29217.0 23528.0 False True 34855.07494541312 25378.92478333244 30172.676565597372 25016.23488740122 23922.309176519047 27554.99360758574 26226.65714812366 35349.11096514841 29644.243351866477 27793.44015245449 1.2540755931695993 0.9131264299821187 1.0856042433067707 0.9000769516180959 0.8607178184959743 0.9914207617495062 0.9436275971690945 1.2718508673719062 1.0665913679364567 1.0 14.762456795725862 -7.729122222884851 24.999841669011033 1.1269162514915279 0.9844959086754904 0.16058299059950976 0.12365614020658623 278.6656185514011 215569.6904260656 0.056596481297041916 0.032672839749398955 1.8658545121284877e-08 7.729122222884851 -0.14242034281603744 VCEEIAIIPSKK ddPTM_PC-9_Lapatinib_30min_R1 1 VCEEIAIIPSKK 12 1 H3BNC9;P08708;H0YN88;A0A075B716;H0YN73 H3BNC9 RPS17 40S ribosomal protein S17 0 71.548 0.017174000000000002 8371100.0 44269.0 49936.0 62073.0 51650.0 58252.0 54413.0 55729.0 36265.0 50840.0 50586.0 False True 43637.71594205965 49820.37626005872 56969.59754870917 55448.51329934905 54825.73188783839 52085.88283289826 58614.37493590879 37950.00429189142 45113.86383106601 59329.72269839197 0.7355118810161299 0.8397203626473214 0.9602201891001462 0.9345823775584895 0.9240854228587916 0.8779053813833174 0.9879428433178473 0.6396457385249162 0.7603922920794091 1.0 15.856467419340618 -11.197648815927764 7.3942350812672215 1.0005622925330793 0.8571800523779393 0.1508848152613439 0.10507625707559698 0.001042258896161744 4.584287073201558e-05 0.10886888434194607 0.026303437269978528 6.3438248538292706e-12 11.197648815927764 -0.14338224015514 VCEVCSAYLGLHDNDRR ddPTM_PC-9_AZD4547_30min_R2 2 VCEVCSAYLGLHDNDRR 17 1 Q9NQ29-3;Q9NQ29;B8ZZ10;A8MYV2;Q9NQ29-2;Q96HJ9-2;A0A0A6YYJ8;Q9Y383-3;Q9Y383-2;Q9Y383 Q9NQ29-3;Q96HJ9-2 LUC7L;LUC7L2 Putative RNA-binding protein Luc7-like 1;Putative RNA-binding protein Luc7-like 2 0 ; 103.3 0.00034882 15701900.0 66160.0 44651.0 85783.0 144646.0 112044.0 88810.0 74852.0 108588.0 81407.0 101965.0 False True 87197.50378651152 59083.56255210482 84645.46137038346 111300.09945842267 96488.62462021981 83256.69666065075 81513.6829924622 91808.21970400261 85710.00782431551 98395.2363857306 0.8861963951657014 0.600471778130442 0.8602597491463403 1.131153331672503 0.9806229261136539 0.8461456033731806 0.8284311922673872 0.9330555327302079 0.8710788344296847 1.0 16.586300851526175 -5.514985450886297 24.97491329123773 0.9365819450539937 0.7400919792772634 0.3634400833619492 0.10432554501045052 365.3202954756937 1155896.062359503 0.02867177077380706 0.05270490996350383 3.0550234565354925e-06 5.514985450886297 -0.19648996577673028 VCNPIITK ddPTM_PC-9_AZD4547_30min_R2 1 VCNPIITK 8 0 P11142;E9PKE3;E9PNE6;A8K7Q2;E9PS65 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 88.948 0.041968 0.0 32220.0 41281.0 59115.0 61592.0 61799.0 54009.0 51176.0 48744.0 44373.0 46013.0 False True 42465.28978236703 54624.27595604661 58331.096474945196 47392.91598691408 53219.27557838857 50631.80869209646 55730.56485895152 41211.73482568886 46718.46619072507 44402.0988752672 0.9563802355753275 1.2302183306580887 1.3137013328763318 1.0673575616334845 1.1985756738187145 1.1403021473000532 1.2551335695978663 0.9281483504070247 1.0521679689504078 1.0 15.438340253543098 -7.76537631524663 24.999994061547067 0.992618606068814 1.170583140496258 0.39081079615172376 0.09858192320670935 101.49438159589627 644482.1975300054 0.05030583956208666 0.02559453307067256 1.716420467919492e-08 7.76537631524663 0.17796453442744387 VCNPIITK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VCNPIITK 8 0 P11142;E9PKE3;E9PNE6;A8K7Q2;E9PS65 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 101.64 0.020839 5985200.0 68807.0 58693.0 68144.0 75034.0 84026.0 73911.0 72541.0 68577.0 82213.0 57238.0 False True 80454.66609980336 64519.65315147624 69768.81139755918 70830.08824351021 67561.70848568807 70034.97704712067 65669.39132864028 66776.92641333774 83415.20959328464 67614.79630424127 1.1898973375263526 0.9542238781754507 1.0318571556974845 1.0475530817959036 0.9992148490943561 1.0357936557553098 0.971228117484117 0.987608187309573 1.2336827758520106 1.0 16.045051368940396 -8.901175725034442 0.0016212985962477018 3.3365357668335206e-05 2.0685207125708076 0.0 0.08833573619800324 1439855.6843365624 1055.826334680608 675941.8311621201 671085.4994466999 1.2555218493378932e-09 8.901175725034442 2.0684873472131393 VCNPIITK ddPTM_PC-9_Lapatinib_30min_R1 2 VCNPIITK 8 0 P11142;E9PKE3;E9PNE6;A8K7Q2;E9PS65 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 ; 107.47 0.017553 60879000.0 186348.0 197395.0 197342.0 208470.0 219105.0 176968.0 225006.0 169800.0 172146.0 167793.0 False True 183690.6433479619 196937.944005413 181117.3025221489 223801.57923553354 206217.67467700416 169399.49117255674 236655.70971718628 177689.52788537557 152757.1047022558 196795.79647988122 0.9334073523605008 1.000722309765119 0.9203311542310552 1.1372274369610997 1.0478764199523243 0.8607881580939903 1.2025445357588216 0.9029132281468273 0.7762213799006242 1.0 17.58633987975626 -7.977880548054466 24.999993854087705 0.871929381446163 1.013610562616278 0.20871413473957967 0.10787392134169221 297.4627186376382 336200.1643527124 0.05653833102557863 0.027157257180206354 1.0522512539107163e-08 7.977880548054466 0.14168118117011486 VCTIS(ph)PAPR ddPTM_PC-9_AZD4547_30min_R2 1 VCTISPAPR 9 0 O43439-2;O43439-5;O43439;O43439-4 O43439-2 CBFA2T2 Protein CBFA2T2 1 VCT(0.003)IS(0.997)PAPR 82.831 0.015203 6078500.0 18767.0 13860.0 25886.0 27224.0 23332.0 27739.0 18445.0 23654.0 17650.0 20746.0 True False 24734.51562215028 18339.973952927652 25542.73472638806 20947.92740660718 20092.754539635953 26004.47594493629 20086.56926730031 19998.81781484582 18582.942966810835 20019.68885459095 1.2355094927700696 0.9160968527601215 1.2758807048357574 1.0463662826509597 1.0036496913401454 1.2989450602261932 1.003340731876261 0.99895747431957 0.9282333557621383 1.0 14.28913193157416 -7.495937770989141 24.82408747260017 0.9783870094580734 1.119734324478735 0.2789245851052822 0.11560036996617672 902.3156366602228 831418.9376416808 0.046338102744107205 0.0311340811994002 3.191995195642041e-08 7.495937770989141 0.14134731502066156 VCTLAIIDPGDSDIIR ddPTM_PC-9_Lapatinib_30min_R1 4 VCTLAIIDPGDSDIIR 16 0 P62888;A0A0C4DH44;E5RI99;A0A0B4J213 P62888 RPL30 60S ribosomal protein L30 0 ;;; 145.31 2.0012e-05 16306300.0 126293.5 117754.0 115791.0 106822.0 101470.0 115126.0 98388.0 91084.0 109393.90000000001 92140.0 False True 124492.53153060886 117481.34784778392 106271.11094618592 114678.04622774577 95501.73409769553 110202.32935181377 103482.0492238186 95316.09515849009 97072.80701316385 108066.27623116752 1.1520016777880224 1.0871231242989845 0.9833882932993683 1.0611825467404359 0.8837329963457348 1.0197661397721982 0.9575794857820151 0.8820151714545695 0.8982710462375215 1.0 16.72155685222957 -3.8602189116677925 0.47648054402671053 0.9295663274010583 1.6119738210493422 0.62718187783337 0.052570920258580414 6.768583703854093 0.6071434532890347 0.03213707669631425 3.1257791050672714 0.00013796886396581933 3.8602189116677925 0.6824074936482839 VDATEESDLAQQYGVR ddPTM_PC-9_Lapatinib_30min_R1 4 VDATEESDLAQQYGVR 16 0 P07237;H7BZ94;I3NI03;I3L3U6 P07237 P4HB Protein disulfide-isomerase 0 ;;; 186.13 9.543e-15 17715300.0 35100.1 38772.9 43535.1 42202.6 46226.3 42687.9 42477.5 33302.9 44793.8 32445.4 False True 34599.56613743001 38683.12373224987 39955.81212834581 45306.31998774657 43507.35991840257 40862.23802735518 44676.77710599623 34850.27431221371 39748.650544374636 38053.54415922202 0.9092337363547526 1.0165445712597383 1.049989245710318 1.1905939640780314 1.143319521996714 1.0738089954612675 1.1740503570196132 0.9158220366122712 1.0445452959140946 1.0 15.21574320654548 -10.778663654150428 14.491302860983051 0.9999999999989717 1.062289760745834 0.03234941266296476 0.09115297380100978 0.0 0.0 0.0930108324434203 0.022558440381814586 1.6647014041303797e-11 10.778663654150428 0.06228976074686221 VDCTAHSDVCSAQGVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VDCTAHSDVCSAQGVR 16 0 Q8NBS9-2;Q8NBS9 Q8NBS9-2 TXNDC5 Thioredoxin domain-containing protein 5 0 78.902 0.021436 0.0 7827.4 7993.1 7107.3 12269.0 12587.0 12988.0 11345.0 12129.0 14259.0 10008.0 False True 9152.42422180303 8786.602143442395 7276.764986585351 11581.607706634686 10120.667706535527 12306.886415932733 10270.319469312866 11810.626601737775 14467.510899622275 11822.371176715598 0.7741614676951538 0.7432182607113358 0.6155080802163518 0.9796349254745866 0.8560607305637966 1.040982915523021 0.8687190848431887 0.9990065804226351 1.2237402026520985 1.0 13.529231801004618 -6.35467062277398 0.6441378526806717 1.062599358103584 0.693655684899782 0.5800477208326604 0.10728252907529252 0.6351569575801088 0.5700836217173971 0.07454527033150522 0.12654225462641697 4.419054698380974e-07 6.35467062277398 -0.36894367320380195 VDCTAHSDVCSAQGVR ddPTM_PC-9_Lapatinib_30min_R1 1 VDCTAHSDVCSAQGVR 16 0 Q8NBS9-2;Q8NBS9 Q8NBS9-2 TXNDC5 Thioredoxin domain-containing protein 5 0 175.66 2.6349e-29 0.0 18853.0 13217.0 22710.0 15893.0 18814.0 19704.0 16108.0 16576.0 18468.0 12094.0 False True 18584.152762783244 13186.396848550057 20842.87146313511 17061.824237493798 17707.397509747163 18861.30585226742 16941.993422950676 17346.181473663095 16387.939363338457 14184.431785757966 1.3101795717642257 0.9296387086714325 1.4694188514525215 1.202855672697789 1.2483684772996313 1.329718816879596 1.194407620893314 1.2229028089147511 1.1553469050337952 1.0 13.792020738389546 -8.708198655420857 1.322060517738608 1.0002044270191017 1.2398728944445683 0.24600617984706974 0.12854506280350766 1.0333242522966506 3.541161723088322 0.11787391729129937 0.035396484812732276 1.957948861692809e-09 8.708198655420857 0.23966846742546655 VDCTANTNTCNK ddPTM_PC-9_AZD4547_30min_R2 1 VDCTANTNTCNK 12 0 H7BZJ3;P30101 H7BZJ3;P30101 PDIA3 Protein disulfide-isomerase A3 0 117.86 0.0024578000000000004 0.0 4754.9 4126.6 5251.2 7032.5 6697.8 8379.9 4373.8 5315.3 6467.0 5623.9 False True 6266.859291935976 5460.442749938766 5181.56565692687 5411.265776041906 5767.926082443579 7855.90352828046 4763.059726826678 4493.942518442971 6808.832417357836 5427.008972781932 1.1547538106839594 1.0061606268433523 0.9547737405473193 0.997099102503979 1.0628186007009472 1.4475567605803046 0.8776583474829032 0.8280698522853809 1.2546197088499687 1.0 12.405941578633957 -11.41617635768125 2.577302989132277 0.9699522720231624 1.0566079018745858 0.010386212519664095 0.17390511305395193 60337636.26135014 38596424.46641291 11036290.637032522 0.04354236097641365 3.835514618358864e-12 11.41617635768125 0.08665562985142339 VDCTANTNTCNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VDCTANTNTCNK 12 0 H7BZJ3;P30101 H7BZJ3;P30101 PDIA3 Protein disulfide-isomerase A3 0 98.156 0.01653 0.0 738.14 1032.7 2428.5 3375.6 3276.0 2263.3 914.03 2992.8 2235.0 2641.0 False True 863.0925230704561 1135.2196311234636 2486.4046501375387 3186.4760758428592 2634.091316962771 2144.6085636880625 827.4464613958605 2914.242171133714 2267.682646795412 3119.792393855505 0.2766506273848011 0.3638766583825584 0.7969775985846249 1.0213743972575513 0.8443162186530963 0.6874202808853285 0.2652248473409748 0.9341141342845035 0.7268697273772637 1.0 11.607234313005891 -5.2205502265364805 5.052047620759591 0.771246987919197 0.3066786318724807 0.4539523164569538 0.20368027859835686 0.19224666825263054 12.258997484548496 0.055482568652157956 0.14998277316647307 6.017966605649972e-06 5.2205502265364805 -0.4645683560467163 VDCTANTNTCNK ddPTM_PC-9_Lapatinib_30min_R1 3 VDCTANTNTCNK 12 0 H7BZJ3;P30101 H7BZJ3;P30101 PDIA3 Protein disulfide-isomerase A3 0 ;; 199.82 2.7859000000000002e-05 8061900.0 26594.5 21975.9 26171.4 23597.6 21496.3 20067.9 23359.3 18090.4 22541.3 20891.4 False True 26215.257553165986 21925.016153745288 24019.68851652551 25333.046223285965 20231.92989735186 19209.642697559742 24568.73025606729 18930.946026252084 20002.4614235879 24502.45065395932 1.069903493466679 0.8948091137244042 0.9802973937484167 1.0338984692207687 0.8257104639483319 0.7839886290906857 1.0027050193078242 0.7726143924788623 0.816345340557016 1.0 14.580638429573268 -6.265485506290131 24.99113465131954 0.8581699766891377 0.9865594238437065 0.3413585566503994 0.08618366551531677 400.72407180555285 2475093.0813662983 0.025783931131546377 0.030313568614631536 5.426433606638627e-07 6.265485506290131 0.1283894471545688 VDDDS(ph)LGEFPVTNSR ddPTM_PC-9_AZD4547_30min_R2 6 VDDDSLGEFPVTNSR 15 0 J3KMZ8;Q92785-2;Q92785 J3KMZ8 DPF2 Zinc finger protein ubi-d4 1 VDDDS(0.976)LGEFPVT(0.024)NSR;VDDDS(1)LGEFPVTNSR;VDDDS(1)LGEFPVTNSR;VDDDS(1)LGEFPVTNSR;VDDDS(1)LGEFPVTNSR;VDDDS(0.998)LGEFPVT(0.002)NSR 193.54 7.142699999999998e-39 8489500.0 45636.799999999996 46781.5 56542.1 66832.4 51499.8 51247.9 50718.6 66001.79999999999 46750.100000000006 46948.8 True False 60148.35309559062 61902.705012906576 55792.31481004817 51425.22273028703 44349.94172125594 48043.36071157938 55232.45714505272 55802.738380480754 49221.214843779286 45305.13680210255 1.32762766743923 1.366350691827814 1.2314787847072328 1.1350859165246017 0.9789164066534222 1.0604395903589845 1.2191212971348862 1.2317088595104082 1.086437837254141 1.0 15.467387015224368 -5.559734666199742 2.5925551329676697 1.108592762765624 1.3461772856226206 0.6198019464727877 0.07765853522155193 0.20552374528338868 2.7665626098306837 0.024318973322276827 0.0529956307069122 2.7559119235584707e-06 5.559734666199742 0.2375845228569966 VDDDS(ph)LGEFPVTNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 VDDDSLGEFPVTNSR 15 0 J3KMZ8;Q92785-2;Q92785 J3KMZ8 DPF2 Zinc finger protein ubi-d4 1 VDDDS(1)LGEFPVTNSR;VDDDS(1)LGEFPVTNSR;VDDDS(1)LGEFPVTNSR;VDDDS(1)LGEFPVTNSR;VDDDS(1)LGEFPVTNSR;VDDDS(1)LGEFPVTNSR 183.76 1.8809e-14 11185000.0 85286.1 98320.79999999999 93624.4 103751.8 103748.29999999999 72251.2 99011.4 75793.90000000001 70030.3 55073.1 True False 99723.35225274246 108081.43924446957 95856.76076851443 97938.92301387386 83419.56537840326 68462.21988103166 89632.32341154036 73804.39043527537 71054.36065318868 65057.41707158024 1.5328513909954433 1.6613238598998115 1.4734178681432561 1.50542286217904 1.2822452709215282 1.0523353517970941 1.3777418078698278 1.1344500559263084 1.092179244912386 1.0 15.98942592476904 -6.201053112275952 0.4713625293033228 1.0530506118898793 1.714956219707241 0.7799484021886873 0.10321045572202804 0.7078876629562916 0.28970377403605263 0.09094651902609599 0.22636613017571297 6.294292017691836e-07 6.201053112275952 0.6619056078173617 VDDDS(ph)LGEFPVTNSR ddPTM_PC-9_Lapatinib_30min_R1 9 VDDDSLGEFPVTNSR 15 0 J3KMZ8;Q92785-2;Q92785 J3KMZ8 DPF2 Zinc finger protein ubi-d4 1 VDDDS(1)LGEFPVTNSR;VDDDS(0.922)LGEFPVT(0.078)NSR;VDDDS(1)LGEFPVTNSR;VDDDS(1)LGEFPVTNSR;VDDDS(0.995)LGEFPVT(0.002)NS(0.002)R;VDDDS(1)LGEFPVTNSR;VDDDS(1)LGEFPVTNSR;VDDDS(1)LGEFPVTNSR;VDDDS(0.994)LGEFPVT(0.005)NS(0.001)R 213.71 1.6499999999999997e-63 9861100.0 88529.90000000002 101079.2 109985.40000000001 75528.59999999999 75754.6 80983.09999999999 71589.3 74274.5 84953.70000000001 62158.6 True False 87267.44739160466 100845.15732268775 100942.8249679214 81083.22520002346 71298.863367274 77519.64159382641 75295.84366486478 77725.56442239303 75385.31970387948 72902.6311888717 1.1970411214036631 1.3832855642949875 1.3846252641609722 1.1122126029986212 0.9780012354088735 1.0633311902418616 1.0328275185266342 1.0661558184508644 1.0340548547359802 1.0 16.153683264535594 -5.8886455013413554 4.587406865455551 1.0350945591884075 1.3264056875030983 0.8482187281360094 0.05519779707822881 0.07372444279207309 2.62996449369454 0.015618192946292046 0.023807752749967607 1.292273678831158e-06 5.8886455013413554 0.29131112831469075 VDDFLANEAK ddPTM_PC-9_Lapatinib_30min_R1 2 VDDFLANEAK 10 0 P52209-2;P52209;K7EMN2;K7EM49;K7EPF6 P52209-2 PGD 6-phosphogluconate dehydrogenase, decarboxylating 0 ; 128.81 0.0012311 38748000.0 154983.0 165802.0 149305.0 176245.0 158802.0 142628.0 168228.0 145438.0 143753.0 151930.0 False True 152772.913999599 165418.09565584437 137029.71923396678 189206.64523608467 149461.57857674442 136528.13292210698 176938.0226940741 152195.58042752265 127562.02335380082 178190.89806600058 0.8573553175707833 0.9283195575711995 0.7690051552645074 1.061819920600007 0.8387722392048609 0.7661902734871339 0.9929689148799149 0.8541153452807143 0.7158728349107528 1.0 17.443064120778075 VDDKPS(ph)SPGDSSK ddPTM_PC-9_AZD4547_30min_R2 3 VDDKPSSPGDSSK 13 1 Q9HC52;C9JM54;C9J6K3 Q9HC52 CBX8 Chromobox protein homolog 8 1 VDDKPS(0.46)S(0.46)PGDS(0.04)S(0.04)K;VDDKPS(0.696)S(0.304)PGDSSK;VDDKPS(0.953)S(0.046)PGDSSK 130.66 0.00037566 39028600.0 136865.0 131925.0 124069.0 149773.0 132313.0 144035.0 137938.0 112470.0 137789.0 148979.0 True False 180385.22303115024 174567.17631601595 122423.76399475537 115245.14881978306 113943.62383862711 135028.46868051816 150214.21477868658 95090.34580348818 145072.24523818132 143763.29055567825 1.2547377173541296 1.2142680905624348 0.8515648433028996 0.8016312674420153 0.7925780176442035 0.9392416392154215 1.0448718459216815 0.6614369039268793 1.0091049298986108 1.0 17.133335810197728 -5.2445844808861555 7.385757171509745 0.876320996812741 1.236680680296177 0.604355191336019 0.11200554994008638 0.10815147699501937 32.124942874762 0.028069971885592886 0.07050163860897041 5.693974516400886e-06 5.2445844808861555 0.36035968348343594 VDDKPS(ph)SPGDSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VDDKPSSPGDSSK 13 1 Q9HC52;C9JM54;C9J6K3 Q9HC52 CBX8 Chromobox protein homolog 8 1 VDDKPS(0.777)S(0.19)PGDS(0.019)S(0.013)K;VDDKPS(0.63)S(0.343)PGDS(0.018)S(0.009)K 68.57600000000001 0.015336 32890000.0 94136.0 90170.0 71885.0 122864.0 114488.0 101294.0 108488.0 112438.0 100154.0 78601.0 True False 110071.36552924984 99121.48168723022 73599.01102538063 115980.32841046256 92054.89825898454 95981.96432210418 98211.2312548978 109486.6216379087 101618.56277724734 92850.7390948265 1.18546569044363 1.0675357315788252 0.7926593987605799 1.2491050641181682 0.9914288152835361 1.033723212736948 1.0577323585394054 1.1791680142264924 1.0944292287589272 1.0 16.50262577365411 -7.550684863885021 24.930192309669174 1.1057692427396886 1.0479974001354224 0.014431346427690617 0.12042754261194046 785.8364254174885 704549.1931362739 0.0556498436166292 0.03213025819767075 2.8139419640511177e-08 7.550684863885021 -0.057771842604266155 VDDKPS(ph)SPGDSSK ddPTM_PC-9_Lapatinib_30min_R1 3 VDDKPSSPGDSSK 13 1 Q9HC52;C9JM54;C9J6K3 Q9HC52 CBX8 Chromobox protein homolog 8 1 VDDKPS(0.862)S(0.135)PGDS(0.003)SK;VDDKPS(0.729)S(0.148)PGDS(0.102)S(0.021)K;VDDKPS(0.804)S(0.195)PGDS(0.001)SK 90.561 0.0026183000000000005 100423000.0 447933.0 379224.0 367178.0 382306.0 368244.0 363982.0 336319.0 351137.0 323562.0 335593.0 True False 441545.3932791477 378345.93012745277 336990.04218806775 410422.0585754292 346584.61191555957 348415.33834348357 353731.95219849463 367452.10690864094 287119.0403010892 393599.8029004354 1.1218130446849857 0.9612452225316758 0.8561743164117194 1.042739492121263 0.8805507760968855 0.8852020142693474 0.8987096781854189 0.9335678122826481 0.7294694717459462 1.0 18.586369972668244 -1.5739480730184459 1.0003996297818345 0.898601273138303 199.8397370696783 0.40138548526921725 0.07983626378612206 1434.1252342474181 2.2024923923530397 0.02497115132017087 653664.8139903134 0.02667177549991284 1.5739480730184459 198.94113579654 VDDKPSS(ph)PGDSSK ddPTM_PC-9_AZD4547_30min_R2 1 VDDKPSSPGDSSK 13 1 Q9HC52;C9JM54;C9J6K3 Q9HC52 CBX8 Chromobox protein homolog 8 1 VDDKPS(0.03)S(0.969)PGDSSK 92.8 0.021419999999999998 9873400.0 23667.0 19176.0 20228.0 26344.0 22641.0 24843.0 23415.0 22448.0 21890.0 26860.0 True False 31192.613695818774 25374.26699288172 19959.763503259586 20270.797810742704 19497.687962107735 23289.56328274459 25498.889639134555 18979.177403722788 23047.060710679278 25919.639575547713 1.203435472353 0.9789590985215515 0.770063312226355 0.7820632594700869 0.7522360758635559 0.8985295962493126 0.9837671378420675 0.7322315323252999 0.8891736570450465 1.0 14.66175803657657 -4.879455271214096 2.938155837126289 0.8424549946679836 1.2276380656669454 0.5900103077342749 0.08969013810836124 0.21667035960815606 3.063923986920225 0.02314627318443569 0.17852874404158564 1.3199112447889936e-05 4.879455271214096 0.3851830709989619 VDDKPSS(ph)PGDSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VDDKPSSPGDSSK 13 1 Q9HC52;C9JM54;C9J6K3 Q9HC52 CBX8 Chromobox protein homolog 8 1 VDDKPS(0.399)S(0.591)PGDS(0.009)S(0.001)K;VDDKPS(0.205)S(0.793)PGDS(0.001)S(0.001)K 78.964 0.006798 30120000.0 109490.0 118129.0 96960.0 135450.0 116390.0 110390.0 133608.0 127774.0 108699.0 107239.0 True False 128024.49447392687 129856.06643263642 99271.89412284746 127861.17563482496 93584.21501260612 104600.95406951135 120951.68300184663 124420.06788774372 110288.51723669557 126680.58179654318 1.0106086714974367 1.0250668617957033 0.783639392202068 1.0093194538700327 0.7387415946897697 0.8257062967827771 0.9547768196715617 0.9821557978599278 0.8706031790556955 1.0 16.95083587268963 -10.608645245489237 14.942433279065979 0.999999984918336 0.9094489681706167 0.0697002029169419 0.09716310057409643 0.0 0.0 0.09559149527731334 0.02318434305524087 2.4623781825095694e-11 10.608645245489237 -0.09055101674771926 VDDKPSS(ph)PGDSSK ddPTM_PC-9_Lapatinib_30min_R1 1 VDDKPSSPGDSSK 13 1 Q9HC52;C9JM54;C9J6K3 Q9HC52 CBX8 Chromobox protein homolog 8 1 VDDKPS(0.084)S(0.916)PGDSSK 130.66 0.00037566 12730000.0 20081.0 17889.0 18648.0 16281.0 15715.0 16802.0 18279.0 17380.0 14996.0 13729.0 True False 19794.641257595602 17847.57911959689 17114.833423361677 17478.35905182387 14790.674596878747 16083.417627375013 19225.397180166092 18187.538248809386 13306.992565119328 16102.039357257403 1.2293251071128388 1.1084048873320351 1.06289849649683 1.0854748683710143 0.9185590886170821 0.998843517304285 1.1939728101273674 1.1295176868768502 0.8264165966729978 1.0 13.97495579983207 -4.339132466720898 0.9985207888736085 1.0290647867692144 1.5324128034169706 0.3005838336582709 0.09758092076368889 5.795000144600124 2.5428540533949042 0.03268551194773397 3.8644872841239097 4.580021674654488e-05 4.339132466720898 0.5033480166477562 VDDLLIIEEK ddPTM_PC-9_Lapatinib_30min_R1 1 VDDLLIIEEK 10 0 Q14204 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 145.34 1.1872e-07 0.0 14130.0 11813.0 14395.0 14782.0 16222.0 11663.0 16107.0 17161.0 13990.0 18848.0 False True 13928.503608875355 11785.64772428856 13211.498666306912 15869.117591306456 15267.85385367909 11164.2006777809 16940.941647843712 17958.36270931058 12414.29887876896 22105.851686618647 0.6300821975254048 0.5331460597567826 0.5976471231960829 0.7178695404399426 0.6906702383659432 0.5050337275418768 0.7663555283010691 0.8123804938120222 0.5615842834177575 1.0 14.432140698568453 -14.522878743497351 0.16486199253071265 2.333136262444704 0.5610625791702583 0.567293834567716 0.09404144760366273 97.58374858790285 0.9059380472283804 42.51327317537868 0.3701392925996081 3.0000000123164335e-15 14.522878743497351 -1.7720736832744457 VDDLSS(ph)SPTSSPER ddPTM_PC-9_Lapatinib_30min_R1 1 VDDLSSSPTSSPER 14 0 Q96JK2-2;Q96JK2-3;Q96JK2 Q96JK2-2 DCAF5 DDB1- and CUL4-associated factor 5 1 VDDLS(0.036)S(0.425)S(0.425)PT(0.038)S(0.07)S(0.007)PER 127.71 0.00057427 0.0 13463.0 14587.0 17314.0 11977.0 17675.0 15301.0 12784.0 14607.0 18574.0 14358.0 True False 13271.015151188178 14553.22469772261 15890.509753972752 12857.828534100752 16635.391250386998 14646.6118983731 13445.892967407593 15285.69454547519 16482.000527108972 16839.761169167592 0.7880762095062527 0.8642179987901807 0.9436303516624184 0.7635398391304102 0.9878638469555744 0.8697636356737651 0.7984610252089602 0.9077144498618075 0.9787550049870272 1.0 14.039584056997649 -14.522878745280336 0.08661549646063485 1.4398625364464666 0.7615188711451293 0.3151495038176976 0.06853182286319862 299.81799314589347 1.8095818143217253 24.066787660137436 1.8472210536497145 3.0000000000000132e-15 14.522878745280336 -0.6783436653013373 VDDLSSSPT(ph)SSPER ddPTM_PC-9_Lapatinib_30min_R1 1 VDDLSSSPTSSPER 14 0 Q96JK2-2;Q96JK2-3;Q96JK2 Q96JK2-2 DCAF5 DDB1- and CUL4-associated factor 5 1 VDDLS(0.062)S(0.262)S(0.262)PT(0.399)S(0.013)S(0.002)PER 130.19 0.00027448 0.0 11529.0 17441.0 16431.0 13349.0 17149.0 18521.0 16353.0 17395.0 17886.0 14356.0 True False 11364.594345840334 17400.616436071836 15080.106605494191 14330.72999095859 16140.329536231216 17728.900004559717 17199.678324156477 18203.235203569577 15871.490332070165 16837.415471832424 0.6749607363940352 1.0334493714419293 0.8956307237724185 0.8511240941302834 0.958598994200305 1.0529466374586214 1.0215153479422117 1.0811181344323333 0.942632220403531 1.0 14.039383082554071 -6.495215396138209 3.8480748996154626 1.0242850832312054 0.8790200915287945 0.40348371969203045 0.08835203058201699 0.2409515818445287 7.738892151359795 0.028107348335711647 0.030453095231093994 3.1973089536571736e-07 6.495215396138209 -0.14526499170241092 VDDSPSTSGGSS(ph)DGDQR ddPTM_PC-9_AZD4547_30min_R2 2 VDDSPSTSGGSSDGDQR 17 0 F8WF15;F8W8F0;C9J180;Q96LR5 F8WF15 UBE2E2 Ubiquitin-conjugating enzyme E2 E2 1 VDDSPSTSGGS(0.012)S(0.988)DGDQR;VDDSPST(0.001)S(0.001)GGS(0.231)S(0.768)DGDQR 197.29 1.6475999999999998e-53 0.0 13342.599999999999 17929.5 17418.8 19308.2 16261.3 17349.1 18525.5 23646.0 18182.7 16442.9 True False 17585.26925667941 23724.860244517775 17187.815330758272 14856.992798716294 14003.69918546982 16264.258034402605 20174.23361135115 19992.0540310241 19143.800401282246 15867.23907582924 1.1082753069163285 1.4952103596055437 1.0832265933990168 0.9363313130731189 0.8825542439076138 1.0250213005977926 1.2714394429263252 1.2599579508118866 1.2064985162065296 1.0 13.953763498388685 -5.312663017258897 23.681508935487088 1.0846567084510987 1.3017428723233009 0.2503701826082584 0.15129247615325692 255.13722690829707 117953.39187514804 0.04329927292864018 0.09013487605913745 4.867847707965546e-06 5.312663017258897 0.21708616387220214 VDDSPSTSGGSS(ph)DGDQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VDDSPSTSGGSSDGDQR 17 0 F8WF15;F8W8F0;C9J180;Q96LR5 F8WF15 UBE2E2 Ubiquitin-conjugating enzyme E2 E2 1 VDDSPSTSGGS(0.013)S(0.986)DGDQR;VDDSPSTSGGS(0.016)S(0.984)DGDQR 197.51 1.5986e-53 0.0 21146.0 27702.0 23459.3 22192.0 29412.0 17356.4 25082.0 18322.2 16848.1 15060.2 True False 24725.600147462366 30452.071483860003 24018.658681890698 20948.654187434742 23648.929735808608 16446.199829804027 22706.051382045407 17841.261663975583 17094.471589026296 17790.4950435224 1.3898208052656225 1.7117045596180722 1.3500837735617708 1.1775194639714224 1.329301386945907 0.9244374476129131 1.2763023921761405 1.002853581102099 0.9608766674118195 1.0 14.118819035567562 -5.884243363053365 0.7093192956393012 1.0252922605882993 1.6116130211420974 0.6448305539485916 0.14026189498868005 0.5985427221927183 0.5541043229995508 0.07416447324436104 0.22688806240600298 1.3054391618426384e-06 5.884243363053365 0.5863207605537981 VDDSPSTSGGSS(ph)DGDQR ddPTM_PC-9_Lapatinib_30min_R1 1 VDDSPSTSGGSSDGDQR 17 0 F8WF15;F8W8F0;C9J180;Q96LR5 F8WF15 UBE2E2 Ubiquitin-conjugating enzyme E2 E2 1 VDDSPSTS(0.001)GGS(0.087)S(0.912)DGDQR 145.79 9.6816e-05 3820100.0 5803.6 8857.1 10247.0 8759.9 7975.4 8220.4 8367.7 12484.0 9381.0 8761.0 True False 5720.839599750109 8836.591929128603 9404.531214563869 9404.132268169755 7506.30265223969 7868.832654688336 8800.938562529458 13064.052215082655 8324.412993690612 10275.3271767013 0.5567549822376242 0.8599815633282272 0.9152536997447722 0.915214874081389 0.7305171429732954 0.7657987448351476 0.856511759789515 1.2714001209328523 0.8101360521702636 1.0 13.326896711041774 -7.5440628069847655 24.98211719844994 1.0372521680288187 0.8030766702225648 0.35263361676764604 0.14266059379502793 258.06509260704223 304329.4529549591 0.06496954989064586 0.037514425784449086 2.857177313007046e-08 7.5440628069847655 -0.2341754978062539 VDDSSGS(ph)IGRR ddPTM_PC-9_AZD4547_30min_R2 1 VDDSSGSIGRR 11 1 P41250 P41250 GARS Glycine--tRNA ligase 1 VDDS(0.011)S(0.032)GS(0.957)IGRR 61.423 0.027226 4754900.0 16476.0 15481.0 21719.0 31275.0 29893.0 21897.0 20104.0 23149.0 22515.0 21075.0 True False 21715.02527791059 20484.930502544958 21430.99186905749 24065.03194393326 25742.872940739635 20527.77712845704 21893.217053391447 19571.853961100278 23705.0969347165 20337.17066473074 1.0677505556645281 1.007265506114401 1.053784335213535 1.1833028468245819 1.2658040474323995 1.0093723196244233 1.0765124320542407 0.9623685754401572 1.1656044651199444 1.0 14.311831362978571 VDDSSGSIGRR ddPTM_PC-9_AZD4547_30min_R2 2 VDDSSGSIGRR 11 1 P41250 P41250 GARS Glycine--tRNA ligase 0 ; 95.48299999999999 0.0039233 3530100.0 90131.0 69437.0 71816.0 83999.0 77660.0 59907.0 51136.0 68702.0 89487.0 134715.0 False True 118790.78315873761 91881.15233545721 70863.67291625917 64634.328321613095 66878.24950917729 56161.00581972309 55687.00493644177 58085.684514903936 94217.10012866867 129998.66885405456 0.9137846118416821 0.7067853320760484 0.5451107579864191 0.49719223197720613 0.5144533409358168 0.43201216069968607 0.42836596272350935 0.44681753303270294 0.7247543452498214 1.0 16.98813732501757 -8.565959338739288 4.659680292611393 0.9998364632798181 0.5534974726908753 0.4776978570194098 0.1414529817349542 0.21684342353871366 16.225688897053058 0.14879276406350325 0.03877449202690345 2.716693610123068e-09 8.565959338739288 -0.4463389905889428 VDDSSGSIGRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VDDSSGSIGRR 11 1 P41250 P41250 GARS Glycine--tRNA ligase 0 97.59700000000001 0.013015 0.0 7291.7 15313.0 11341.0 9344.4 31250.0 28616.0 12728.0 23541.0 25469.0 27566.0 False True 8526.04079236032 16833.1734399086 11611.41245098201 8820.863562953546 25126.786830002016 27115.32658441106 11522.311697259946 22923.07369375127 25841.435942385844 32563.49758766408 0.2618281641708602 0.5169338273504581 0.356577558037891 0.2708819450124155 0.7716243245172998 0.8326908530453151 0.35384134232635084 0.7039499867002966 0.793570649860882 1.0 14.990968044797956 -6.91498986393969 0.16117590033924198 1.166691950184321 1.1506609234662811e-17 0.5687657550782902 0.16605095162743463 6.421200390526994 0.5270465049656191 1.1467384960166043 2.258019990509433 1.2162143857146118e-07 6.91498986393969 -1.166691950184321 VDDSTGTVIS(ph)DVEEDAGELSR ddPTM_PC-9_AZD4547_30min_R2 1 VDDSTGTVISDVEEDAGELSR 21 0 S4R403;Q9Y2D8-2;Q9Y2D8-3;Q9Y2D8 S4R403 SSX2IP Afadin- and alpha-actinin-binding protein 1 VDDS(0.002)T(0.163)GT(0.096)VIS(0.74)DVEEDAGELSR 121.47 0.00014916 0.0 832.78 666.95 550.29 2263.2 915.32 1163.4 947.91 763.69 924.12 1795.7 True False 1097.5867170999263 882.5285445818976 542.9927950469014 1741.4542060914393 788.2436175732715 1090.6524140862646 1032.272153655009 645.6792583503681 972.9670965716285 1732.833089568541 0.63340590834009 0.5092980679412342 0.31335550914606636 1.0049751569119938 0.45488721465351095 0.6294041940056827 0.5957135513334612 0.37261480187404317 0.5614892181069142 1.0 10.75891698217886 -10.535553241026541 4.724765034373732 1.0000094711039256 0.5619317461612134 0.349182748199376 0.17859166942793267 122853992.18048775 13950.647409859623 12665.926305145205 0.04212031941088174 2.9137129149987735e-11 10.535553241026541 -0.43807772494271213 VDDSTGTVIS(ph)DVEEDAGELSR ddPTM_PC-9_Lapatinib_30min_R1 1 VDDSTGTVISDVEEDAGELSR 21 0 S4R403;Q9Y2D8-2;Q9Y2D8-3;Q9Y2D8 S4R403 SSX2IP Afadin- and alpha-actinin-binding protein 1 VDDSTGTVIS(1)DVEEDAGELSR 223.76 5.925499999999999e-41 873420.0 2134.7 875.94 2535.8 842.43 2237.1 1059.5 2155.8 1171.1 2005.2 919.43 True False 2104.258786543964 873.9118147475932 2327.316312471072 904.385112464098 2105.518176307823 1014.1876548151303 2267.416775589589 1225.51358131074 1779.3532603079 1078.3522504365344 1.951364951194868 0.8104140501341928 2.1582152877493757 0.8386731813264064 1.9525328346609148 0.9404975548616611 2.102668005442287 1.136468701034038 1.6500668122012905 1.0 10.074612805004085 -10.997120663733803 4.048378558691036 0.9963763629116803 1.4871227573860002 0.0804325553290246 0.5087355071845961 0.014753091855033276 0.0019159643435929556 0.43673241792095957 0.10526282946642776 1.00665194331357e-11 10.997120663733803 0.4907463944743199 VDEEPTTLPS(ph)GEAKPR ddPTM_PC-9_AZD4547_30min_R2 1 VDEEPTTLPSGEAKPR 16 1 J3KP36;A0A0A0MR88;A0A096LPC5;Q9Y4E1-3;Q9Y4E1-6;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1;A0A0A0MT65;E7ESD2;Q641Q2-2;Q641Q2;F8W7U3 J3KP36;E7ESD2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 VDEEPT(0.001)TLPS(0.999)GEAKPR 71.872 0.0081425 6849600.0 20453.0 21958.0 25698.0 28048.0 27038.0 27741.0 22981.0 29047.0 23709.0 28164.0 True False 26956.628551171743 29055.494087906598 25357.22772922508 21581.966937280275 23284.24040985241 26006.350884620126 25026.264479903955 24558.453583657152 24962.209337117183 27177.986932454434 0.9918552326251082 1.0690819066223831 0.9330061049865652 0.7940973329230758 0.8567316066388887 0.9568902564142745 0.9208284830698402 0.9036156226247507 0.9184716071560365 1.0 14.730150979506092 -5.401515777169426 5.387108526426736 0.9010547097604822 1.0286331865220308 0.43460435208951165 0.05492379294712519 0.19163150481136007 7.578109566219166 0.014822627394554155 0.031571880621578036 3.967201165123245e-06 5.401515777169426 0.12757847676154865 VDEGAGDSAAVASGGAQT(ph)LALAGSPAPSGHPK ddPTM_PC-9_AZD4547_30min_R2 1 VDEGAGDSAAVASGGAQTLALAGSPAPSGHPK 32 0 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 VDEGAGDSAAVAS(0.012)GGAQT(0.759)LALAGS(0.22)PAPS(0.009)GHPK 80.722 5.7844e-07 21761000.0 17097.0 13163.0 36161.0 58334.0 52026.0 40110.0 29408.0 55714.0 31658.0 43936.0 True False 22533.490360308166 17417.68233350554 35681.48151282232 44885.99755131583 44803.087934129086 37601.915359291765 32025.2550291552 47104.68148035514 33331.377248912046 42397.81401307758 0.5314776453653418 0.4108155747872536 0.8415877644497518 1.0586865996787185 1.0567310833598544 0.8868833508183577 0.7553515617403537 1.1110167487839286 0.7861579193359121 1.0 15.371702262408865 -5.363517449553395 4.182970888765469 0.9487762035952834 0.4715205637157061 0.7316076527748918 0.11413296019836114 0.10624970366067442 3.1797490245776157 0.030252222185433206 0.06791960470852623 4.329946700603459e-06 5.363517449553395 -0.47725563987957725 VDEGAGDSAAVASGGAQTLALAGS(ph)PAPSGHPK ddPTM_PC-9_AZD4547_30min_R2 1 VDEGAGDSAAVASGGAQTLALAGSPAPSGHPK 32 0 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 VDEGAGDSAAVASGGAQTLALAGS(0.994)PAPS(0.006)GHPK 160.98 1.0367999999999999e-16 18929000.0 20088.0 23411.0 49458.0 71314.0 57019.0 56539.0 39575.0 63401.0 37941.0 59966.0 True False 26475.566143643355 30978.14792294293 48802.15460471687 54873.65909031675 49102.89606958263 53003.607392146565 43097.09833306639 53603.8322600423 39946.48380191333 57866.608592229866 0.457527523864573 0.5353371949138657 0.8433560526868314 0.9482784705251416 0.8485532030328109 0.9159618764881914 0.7447662716292884 0.9263344364584041 0.690320113338683 1.0 15.820443473622287 -5.226588950463569 3.73518627208944 0.8639921460317587 0.4761508936604816 0.739457970363358 0.08800247929438172 0.10372351310702893 3.1138194065700104 0.021764235679934435 0.062288038366067396 5.934867801471092e-06 5.226588950463569 -0.3878412523712771 VDEGAGDSAAVASGGAQTLALAGS(ph)PAPSGHPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VDEGAGDSAAVASGGAQTLALAGSPAPSGHPK 32 0 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 VDEGAGDSAAVAS(0.001)GGAQT(0.014)LALAGS(0.956)PAPS(0.029)GHPK;VDEGAGDSAAVASGGAQT(0.003)LALAGS(0.986)PAPS(0.011)GHPK 126.18 1.5284e-16 26123000.0 44589.0 54215.0 77177.0 86939.0 106817.0 87778.0 77296.0 74585.0 67523.0 58459.0 True False 52137.03702710677 59597.10690554719 79017.19237540232 82068.08969004106 85886.9756422506 83174.76715566232 69973.9633054216 72627.22277933965 68510.39613403413 69057.15393881059 0.754983865586233 0.8630113392503019 1.1442289157386505 1.1884082243348613 1.2437085912685077 1.2044337539505454 1.0132760954415145 1.0516973063166255 0.9920825320246919 1.0 16.07550325699338 -5.139422335415191 3.5926822580099556 1.1149181789068876 0.7744129124468305 0.6565104367767646 0.08661674376331108 0.1512939461582213 3.4564787499021308 0.025073322056824412 0.08160975565010922 7.2540018931194235e-06 5.139422335415191 -0.3405052664600571 VDEGAGDSAAVASGGAQTLALAGS(ph)PAPSGHPK ddPTM_PC-9_Lapatinib_30min_R1 2 VDEGAGDSAAVASGGAQTLALAGSPAPSGHPK 32 0 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 VDEGAGDSAAVASGGAQT(0.343)LALAGS(0.653)PAPS(0.004)GHPK;VDEGAGDSAAVASGGAQT(0.008)LALAGS(0.962)PAPS(0.029)GHPK 122.66 2.9335000000000002e-18 26470000.0 46729.0 51324.0 89099.0 66151.0 74095.0 89439.0 62960.0 68439.0 98681.0 47097.0 True False 46062.635890950936 51205.16243133717 81773.62415208628 71015.96521326715 69736.87777637485 85613.90246249209 66219.76073435404 71618.9257888532 87566.50662300216 55237.65369719224 0.8338992120024158 0.9269974194059578 1.4803964085868275 1.2856441296831718 1.2624880513329917 1.5499192440689038 1.1988155959223885 1.2965598825297975 1.5852683950522906 1.0 15.753364419795021 -5.175514999756759 5.546012557184798 1.3412837186223776 0.8627558918106937 0.5453331881325215 0.1653019106216942 0.151353410091511 7.487048311435663 0.0397109939821226 0.10985032179911713 6.675518445161392e-06 5.175514999756759 -0.47852782681168393 VDELT(ph)T(ph)EIK ddPTM_PC-9_AZD4547_30min_R2 1 VDELTTEIK 9 0 P49454 P49454 CENPF Centromere protein F 2 VDELT(1)T(1)EIK 68.786 0.030744999999999998 0.0 5879.8 4652.0 6402.3 8815.4 6875.2 7288.0 6697.5 7504.3 5604.2 8491.1 True False 7749.454092562437 6155.668025181777 6317.401318811495 6783.145726572322 5920.697154590478 6832.280207891263 7293.564525223298 6344.682866658812 5900.426570798946 8193.8291734897 0.9457671045467981 0.751256573068159 0.7709949994138033 0.8278358729418597 0.7225800085930875 0.8338323954807857 0.8901289459171158 0.774324523043071 0.7201061244831874 1.0 13.000322100213 VDENMTAS(ph)TYSLNKIPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VDENMTASTYSLNKIPER 18 1 Q9HCD6;Q9HCD6-2;Q9HCD6-3;Q9HCD6-4;J3KRP9 Q9HCD6 TANC2 Protein TANC2 1 VDENMT(0.002)AS(0.357)T(0.357)Y(0.007)S(0.276)LNKIPER 63.726000000000006 0.026292000000000003 9082200.0 38689.0 34253.0 41403.0 47216.0 52082.0 43739.0 41436.0 44495.0 40996.0 36031.0 True False 45238.283557418494 37653.41146980928 42390.2045417519 44570.640596337355 41876.90597376527 41445.24984189112 37510.882109338716 43327.05339634946 41595.48894318779 42563.13507876094 1.0628513025111361 0.8846484498882317 0.9959370817800652 1.0471653583285543 0.9838773834745529 0.9737358341954551 0.8812997924125353 1.017947886502602 0.9772656282535915 1.0 15.377316799091627 -6.7588373817111265 4.4889494523006315 0.9652968823426371 0.9920703277105111 0.044841374566525594 0.055547509508911914 0.7458527533902499 36.61941241107035 0.019671030484949243 0.01844665841969339 1.7424592019430243e-07 6.7588373817111265 0.02677344536787396 VDENMTAST(ph)YSLNKIPER ddPTM_PC-9_Lapatinib_30min_R1 1 VDENMTASTYSLNKIPER 18 1 Q9HCD6;Q9HCD6-2;Q9HCD6-3;Q9HCD6-4;J3KRP9 Q9HCD6 TANC2 Protein TANC2 1 VDENMT(0.003)AS(0.065)T(0.542)Y(0.012)S(0.378)LNKIPER 57.188 0.022618 9643100.0 39356.0 35247.0 40974.0 37435.0 33504.0 31002.0 30946.0 25780.0 32791.0 19873.0 True False 38794.77622299351 35165.38773706923 37605.27588421392 40188.09477949919 31533.36059139839 29676.11672919177 32548.23246005907 26977.832914517036 29097.732275461953 23308.02157089202 1.6644388329999644 1.5087246950631434 1.6134048859460848 1.7242173325293157 1.3528973489014828 1.2732147445003432 1.3964390911971092 1.1574484274636172 1.24839992047203 1.0 14.50853893051999 -7.190697173947201 0.42855329247891083 1.0210037878962492 1.6851844138845151 0.8007208774825082 0.09903367113733762 0.5239945600071477 0.21826784924650494 0.10852806347336676 0.12331644198712613 6.446185902702833e-08 7.190697173947201 0.6641806259882659 VDFGS(ph)SER ddPTM_PC-9_AZD4547_30min_R2 1 VDFGSSER 8 0 A0A0C4DGE6;E9PNT2;E9PIR1;A0A0G2JRG8;A0A0G2JNY3;Q6ZUM4-2;Q6ZUM4-3;Q6ZUM4 A0A0C4DGE6 ARHGAP27 Rho GTPase-activating protein 27 1 VDFGS(0.771)S(0.229)ER 94.309 0.0067729 21820000.0 37136.0 47491.0 68881.0 61685.0 75453.0 61235.0 55197.0 96238.0 67398.0 56412.0 True False 48944.475523214845 62841.53701287784 67967.59293395413 47464.47627374978 64977.65336358439 57405.96576978889 60109.42606924236 81366.62842923524 70960.52068425591 54437.033050476435 0.899102555384151 1.1543894567988005 1.2485543227701548 0.8719151947487405 1.1936295885805206 1.054538841537516 1.1042009951847713 1.49469256257571 1.3035339493696905 1.0 15.732300818176657 -7.567929300236981 19.690616109881603 1.2993640313590293 1.0789007304211509 0.2269304244157324 0.15849193809910989 19.42685572383195 8489.35241157454 0.07113950631485556 0.041072724221898345 2.704398583325979e-08 7.567929300236981 -0.22046330093787847 VDFGS(ph)SER ddPTM_PC-9_Lapatinib_30min_R1 3 VDFGSSER 8 0 A0A0C4DGE6;E9PNT2;E9PIR1;A0A0G2JRG8;A0A0G2JNY3;Q6ZUM4-2;Q6ZUM4-3;Q6ZUM4 A0A0C4DGE6 ARHGAP27 Rho GTPase-activating protein 27 1 VDFGS(0.835)S(0.165)ER;VDFGS(0.777)S(0.223)ER;VDFGS(0.943)S(0.057)ER 112.3 0.0037321999999999998 40407400.0 82810.0 115775.0 144023.0 118140.0 150889.0 122546.0 122633.0 116622.0 133851.0 98902.0 True False 81629.11421450575 115506.93010069485 132181.984884857 126828.40970348666 142014.00567918803 117304.99324867869 128982.33669212245 122040.68386954235 118775.29086648334 115997.07892136853 0.7037169812684684 0.9957744727261111 1.1395285649775697 1.093375892590023 1.2242894993541666 1.0112754074453612 1.1119446962932256 1.0521013546579963 1.023950706094919 1.0 16.823728949800717 -4.787856868991545 2.9828503292723485 1.0876066789282552 0.6431546206699131 0.7571151840315863 0.0641764724134207 0.1744724761718546 2.261574853516985 0.01623054911826995 0.18692184553623542 1.629833090388876e-05 4.787856868991545 -0.4444520582583421 VDFNVPMK ddPTM_PC-9_Lapatinib_30min_R1 1 VDFNVPMK 8 0 P00558;P07205 P00558 PGK1;PGK2 Phosphoglycerate kinase 1;Phosphoglycerate kinase 2 0 99.44200000000001 0.023951 5343900.0 47422.0 53030.0 56756.0 52459.0 58283.0 52496.0 48798.0 45419.0 47533.0 57295.0 False True 46745.75358387028 52907.21229315351 52089.74076449568 56317.009858093996 54854.90852878677 50250.868454153 51324.52166955223 47529.33255021139 42179.33299531985 67198.36440921146 0.6956382643364225 0.7873288696577423 0.7751638186800167 0.8380711398739661 0.8163131500454696 0.7477989813583125 0.7637763526059385 0.7072989494324081 0.6276839230559899 1.0 16.036138498157115 -6.801651522397755 24.014522958938713 0.7506718120495511 0.7854505830194647 0.0 0.0955242254577758 464.54799756749435 277421.7365811645 0.032350520217816855 0.028530944004581425 1.5788776519327652e-07 6.801651522397755 0.03477877096991355 VDGDS(ph)PESR ddPTM_PC-9_AZD4547_30min_R2 1 VDGDSPESR 9 0 P16144-4;P16144-2;P16144-3;P16144;J3QRK0 P16144-4 ITGB4 Integrin beta-4 1 VDGDS(1)PESR 86.014 0.024331000000000002 0.0 10736.0 20530.0 27437.0 21997.0 17125.0 22361.0 18259.0 22890.0 19511.0 14388.0 True False 14149.824677327515 27165.921013968593 27073.167452982685 16925.931500262195 14747.489349017043 20962.763135106543 19884.01562763004 19352.87645987235 20542.311627504056 13884.280499366358 1.0191255267403505 1.9565955193146938 1.9499150463157406 1.219071560894686 1.0621716659851463 1.5098199100819973 1.4321243098291982 1.3938695966820582 1.4795373536598857 1.0 13.761164796397145 -13.16611928012961 0.14752829078948634 1.8266631570694244e-13 1.6195248354358778 0.15753644640859643 0.3021329548679329 164.21274361629133 2.1037965367436673 52.485162883276026 1.8145551894214362 6.821513137457038e-14 13.16611928012961 1.619524835435695 VDGDS(ph)PESR ddPTM_PC-9_Lapatinib_30min_R1 1 VDGDSPESR 9 0 P16144-4;P16144-2;P16144-3;P16144;J3QRK0 P16144-4 ITGB4 Integrin beta-4 1 VDGDS(0.945)PES(0.055)R 100.09 0.0039328 3243500.0 26830.0 31819.0 20250.0 14798.0 20122.0 15603.0 14506.0 13751.0 19879.0 14052.0 True False 26447.399279980586 31745.325060453535 18585.123167260495 15886.294284680893 18938.4635213741 14935.696062369496 15257.04970159688 14389.92166049355 17640.017684849754 16480.86947688696 1.6047332525186762 1.9261923714021092 1.127678560486422 0.963923311628679 1.1491179848207467 0.9062444237736097 0.9257430090683998 0.8731287921838232 1.0703329523717424 1.0 14.008504735960365 -5.3642162999378415 4.528077983905164 0.9847193588107307 1.762371262472306 0.8914341561197456 0.10724342682970983 0.058857208582164054 1.969919601567371 0.027978616959141382 0.061657794252557324 4.322984715828067e-06 5.3642162999378415 0.7776519036615753 VDGET(ph)ASDSESRAESAPLPVSADDTPEVLNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VDGETASDSESRAESAPLPVSADDTPEVLNR 31 1 O95674 O95674 CDS2 Phosphatidate cytidylyltransferase 2 1 VDGET(0.347)AS(0.323)DS(0.323)ES(0.006)RAES(0.001)APLPVSADDTPEVLNR 46.783 0.012422 3927500.0 1672.0 3415.0 2136.0 1157.6 5828.9 1612.3 4209.3 2938.8 1100.0 1598.2 True False 1955.0365764947082 3754.018631051256 2186.930340825111 1092.743424989836 4686.768888108761 1527.7481497080644 3810.564631307066 2861.6596139159847 1116.0854190044531 1887.9410086557623 1.0355390171257093 1.9884194547604876 1.158367942005896 0.5788016786434885 2.482476341485796 0.8092139228417101 2.0183706025964425 1.5157569017230694 0.5911654092407898 1.0 10.882597971051773 -10.198386330951358 6.932380216329255 0.9999999997470089 1.384874725156734 0.026619858432093135 0.6141577218600088 2.467478630653375e-09 0.0 0.5629158644305722 0.13652715000533 6.333060969081116e-11 10.198386330951358 0.384874725409725 VDGETAS(ph)DSESRAESAPLPVSADDTPEVLNR ddPTM_PC-9_AZD4547_30min_R2 1 VDGETASDSESRAESAPLPVSADDTPEVLNR 31 1 O95674 O95674 CDS2 Phosphatidate cytidylyltransferase 2 1 VDGET(0.301)AS(0.33)DS(0.056)ES(0.301)RAES(0.011)APLPVSADDTPEVLNR 67.283 4.3417e-05 3306100.0 3262.0 3633.3 6032.6 3239.2 6107.7 3928.5 3193.9 4446.3 4818.7 3240.1 True False 4299.248146185017 4807.693171946035 5952.603782369187 2492.4524851411234 5259.751281576136 3682.8502739710243 3478.150912595851 3759.226500809543 5073.406644428976 3126.665085209684 1.3750267550311341 1.5376425171625365 1.903818803787866 0.79716004663607 1.6822240752477011 1.1778844787029823 1.1124155666843976 1.2023118557187704 1.6226255470814959 1.0 11.61040897697133 -5.746026321838453 24.99998620106726 1.248279092852364 1.5987104844895477 0.27906169661015257 0.27676293163012666 334.89357282349425 543193.0861656928 0.07248304454508898 0.12496851591589686 1.7946248544234787e-06 5.746026321838453 0.35043139163718373 VDGETASDS(ph)ESRAESAPLPVSADDTPEVLNR ddPTM_PC-9_AZD4547_30min_R2 1 VDGETASDSESRAESAPLPVSADDTPEVLNR 31 1 O95674 O95674 CDS2 Phosphatidate cytidylyltransferase 2 1 VDGET(0.024)AS(0.066)DS(0.759)ES(0.066)RAES(0.083)APLPVS(0.002)ADDTPEVLNR 61.18600000000001 0.00031882 3979000.0 2081.3 2868.1 6894.2 6680.3 4448.1 5026.6 5577.9 5774.3 2063.7 1940.4 True False 2743.110106270658 3795.1572362476063 6802.778403409746 5140.260044606153 3830.5580947949006 4712.285907380107 6074.322294175897 4882.014615213675 2172.782968872949 1872.4671866117944 1.4649709890159843 2.026821758684538 3.6330561368711014 2.7451803061539297 2.0457277554359963 2.5166186842007785 3.244020689712222 2.607263107263107 1.160385070781706 1.0 10.870724721569221 -6.263717920787778 24.674343989290254 2.254497437669318 2.519283231659111 0.02495567786378583 0.8143924217696716 957.4084657524052 10367791.185964571 0.25889017102154527 0.30762260733768815 5.448564283950286e-07 6.263717920787778 0.2647857939897933 VDGETASDS(ph)ESRAESAPLPVSADDTPEVLNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VDGETASDSESRAESAPLPVSADDTPEVLNR 31 1 O95674 O95674 CDS2 Phosphatidate cytidylyltransferase 2 1 VDGET(0.06)AS(0.047)DS(0.55)ES(0.149)RAES(0.175)APLPVS(0.017)ADDT(0.001)PEVLNR 47.159 0.0077642 3127900.0 14335.0 10862.0 13894.0 14778.0 22413.0 12656.0 12218.0 13167.0 9245.9 10680.0 True False 16761.632370844276 11940.307575542822 14225.285653288429 13950.036570922433 18021.333543066736 11992.297080385324 11060.622589340204 12821.38020158969 9381.103795975705 12616.199457166518 1.3285801661389383 0.9464266648669888 1.127541277512689 1.1057241618828593 1.428428078063547 0.9505475179827795 0.8767000416323727 1.0162632768386222 0.743576052980587 1.0 13.622989753413714 -6.970347975199354 24.970266738616687 0.910937676240939 1.1684385647887063 0.48065888920791 0.14012228797103232 186.56565712548172 157108.29550474693 0.04841072218984478 0.04269369636020045 1.0706611022836889e-07 6.970347975199354 0.2575008885477673 VDGGLQMGS(ph)ERMEMR ddPTM_PC-9_AZD4547_30min_R2 1 VDGGLQMGSERMEMR 15 1 O76081-6 O76081-6 1 VDGGLQMGS(1)ERMEMR 43.03 0.035548 977080.0 0.0 0.0 0.0 1106.2 735.79 352.34 613.38 867.97 0.0 483.48 True False 0.0 0.0 0.0 851.1826806196315 633.6382591598975 330.30812410104386 667.9696317254902 733.8451804663791 0.0 466.5535123598588 0.0 0.0 0.0 1.8244052569967648 1.3581255791107711 0.7079747882088023 1.4317106484674291 1.5729067749475107 0.0 1.0 8.865898753356795 -5.738359132386166 24.790167831578017 1.1565035440588474 1.060779000840623e-06 0.5369233184306722 0.4794837953630483 159.56989478210457 171390.2416840135 0.1283783028278839 0.22216869418085916 1.8265891248399278e-06 5.738359132386166 -1.1565024832798465 VDGIPNDSSDS(ph)EMEDK ddPTM_PC-9_AZD4547_30min_R2 1 VDGIPNDSSDSEMEDK 16 0 Q9H6S0 Q9H6S0 YTHDC2 Probable ATP-dependent RNA helicase YTHDC2 1 VDGIPNDS(0.233)S(0.233)DS(0.534)EMEDK 111.43 0.0031726999999999997 0.0 13828.0 18677.0 16945.0 12809.0 13821.0 16421.0 18059.0 18403.0 18320.0 17004.0 True False 18225.016359732213 24713.975001358565 16720.29822833368 9856.082947077255 11902.192717825668 15394.19227411942 19666.216015081398 15559.239208869854 19288.357798978748 16408.69513561478 1.1106926059083846 1.5061511471267037 1.0189901201858866 0.6006622016935889 0.7253588795121296 0.938172849631815 1.1985240662065948 0.9482313541860378 1.1754961402819724 1.0 14.002172895900939 -5.4421174305207884 7.052930150758081 0.9307499993190158 1.3022636041036368 0.3632979918912619 0.19141709556653888 0.2791587177132742 20.926330465865192 0.05369501293895172 0.1122703343206739 3.613121528762077e-06 5.4421174305207884 0.37151360478462103 VDGPRS(ph)PSYGR ddPTM_PC-9_AZD4547_30min_R2 1 VDGPRSPSYGR 11 1 J3KTL2;Q07955;J3KSR8 J3KTL2 SRSF1 Serine/arginine-rich splicing factor 1 1 VDGPRS(0.638)PS(0.351)Y(0.011)GR 70.628 0.014979 262910000.0 34925.0 16172.0 44799.0 99995.0 64753.0 36628.0 28685.0 45802.0 28494.0 45362.0 True False 46030.42351487178 21399.282739303457 44204.93598885337 76942.69765734955 55763.163668140194 34337.645369736696 31237.90942979177 38724.3533252544 30000.134668346094 43773.8901871182 1.0515497553017947 0.48885951529162575 1.0098470983477275 1.7577304034082006 1.2738909754141567 0.7844321174781398 0.7136196782205223 0.8846450054980541 0.6853431244083156 1.0 15.417782981581496 -6.779507790344127 24.66751469549726 0.8001489010953209 1.1112261182287297 0.19981199506551062 0.30225843830482935 395.08934562713824 539383.4237750405 0.11946957040934453 0.10558207316027259 1.6614688741865625e-07 6.779507790344127 0.31107721713340886 VDGPRS(ph)PSYGR ddPTM_PC-9_Lapatinib_30min_R1 2 VDGPRSPSYGR 11 1 J3KTL2;Q07955;J3KSR8 J3KTL2 SRSF1 Serine/arginine-rich splicing factor 1 1 VDGPRS(0.652)PS(0.203)Y(0.145)GR;VDGPRS(0.998)PS(0.002)YGR 95.477 0.023467 13335000.0 71303.0 43303.0 100700.0 76284.0 59126.0 66977.0 42340.0 36845.0 83200.0 51006.0 True False 70286.20614463126 43202.73456402839 92420.83471324098 81894.17983596418 55648.32492618851 64112.54984101265 44532.15802878893 38556.953209285515 73829.13986515926 59822.319138777086 1.174916104164732 0.7221842146207299 1.5449222972924397 1.36895695477777 0.9302268071067981 1.071716221704528 0.744407082003663 0.6445245481011908 1.2341403831885698 1.0 15.868396220216649 -6.3553229260886495 8.255988694261818 0.9156300434762086 1.1925196620094674 0.21281434523335685 0.2475307978765752 0.5182387742281642 41.289543786395896 0.07999308659046643 0.09070813593002239 4.412422331522691e-07 6.3553229260886495 0.2768896185332588 VDHGAEIITQS(ph)PGR ddPTM_PC-9_AZD4547_30min_R2 3 VDHGAEIITQSPGR 14 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 VDHGAEIIT(0.31)QS(0.69)PGR;VDHGAEIIT(0.021)QS(0.979)PGR;VDHGAEIIT(0.058)QS(0.942)PGR 107.63 0.00043216 381744000.0 263024.0 309035.0 467980.0 512890.0 473390.0 375208.0 322165.0 438236.0 336450.0 348129.0 True False 346660.16076093493 408924.5202411972 461774.27942729945 394651.134571509 407667.9698061991 351746.184446003 350837.0608836984 370516.69586145214 354234.06012371194 335941.10967222 1.0319075301595972 1.2172506087158776 1.3745691317083988 1.1747628474424365 1.2135102197047674 1.0470471589178356 1.0443409597176496 1.1029215692683987 1.0544528488024 1.0 18.357848825803337 -6.759974687953629 24.985948364434407 1.055846867544141 1.21125466504204 0.4672657199296184 0.08109030105481599 36.71234203658885 626273.004785137 0.028466929196724375 0.027016370220090933 1.7379021161911408e-07 6.759974687953629 0.1554077974978989 VDHGAEIITQS(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 VDHGAEIITQSPGR 14 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 VDHGAEIITQS(1)PGR;VDHGAEIITQS(1)PGR;VDHGAEIIT(0.024)QS(0.976)PGR;VDHGAEIIT(0.002)QS(0.998)PGR;VDHGAEIIT(0.226)QS(0.774)PGR;VDHGAEIIT(0.186)QS(0.814)PGR;VDHGAEIIT(0.045)QS(0.955)PGR 169.06 8.442299999999999e-05 356459100.0 217778.40000000002 320578.2 344443.9 387527.4 426563.5 379487.9 393897.4 341509.39999999997 311448.1 295076.5 True False 254643.98180053485 352403.08506848506 352656.748886765 365815.49615878245 342981.4442867055 359586.88647373277 356584.5867017812 332545.14010911866 316002.439260583 348571.53362571076 0.7305357931894879 1.0109921524655785 1.011719876315089 1.0494703694065504 0.9839628632870298 1.031601412580782 1.0229882600931914 0.9540226554076532 0.9065641017028666 1.0 18.41109522986165 -4.759885029749522 24.997633527769032 0.9989915927742445 0.730535462800026 0.8066523272440569 0.03909642228296646 17.553430789183935 282208.9625999752 0.010341523285236702 0.06369706056014973 1.7382609355502198e-05 4.759885029749522 -0.2684561299742185 VDHGAEIITQS(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 4 VDHGAEIITQSPGR 14 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 VDHGAEIITQS(1)PGR;VDHGAEIITQS(1)PGR;VDHGAEIIT(0.048)QS(0.952)PGR;VDHGAEIIT(0.054)QS(0.946)PGR 199.61 5.805e-08 326677000.0 225853.0 272710.0 301112.0 210898.0 340967.0 327030.0 318702.0 357392.0 283201.0 288232.0 True False 222632.29480363269 272078.5567502524 276355.7336859332 226408.1424551039 320911.99142691377 313043.6892441642 335202.83013913746 373997.73704364063 251303.92114126147 338052.5171550012 0.658573101828297 0.8048410910826056 0.8174934948324043 0.6697425132654552 0.9492962635736616 0.9260208794736763 0.9915702831032106 1.106330283209097 0.7433872205898576 1.0 18.36688786400213 -6.278761377474023 22.271627177062832 0.9586868997695651 0.7481632575791419 0.539342491379452 0.09710362317437725 153.55993345957987 197437.5846242322 0.029276777702932286 0.03331450635769388 5.263063652939667e-07 6.278761377474023 -0.2105236421904232 VDIDAPDVDVHGPDWHLK ddPTM_PC-9_AZD4547_30min_R2 2 VDIDAPDVDVHGPDWHLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ; 147.51 5.3795e-05 26669000.0 64616.0 67204.0 84959.0 104763.0 86405.0 95361.0 74663.0 93235.0 79615.0 89207.0 False True 85162.54390370654 88926.37875415235 83832.38814877559 80611.50892221517 74409.1572088653 89398.0615950492 81307.86235860376 78827.67307716049 83823.2863627561 86083.89008249757 0.9892971126431662 1.033019983982261 0.9738452580202372 0.9364296716256898 0.8643795852807777 1.0384993232691453 0.9445189138256094 0.9157076080276674 0.9737395264366533 1.0 16.39345565349324 -5.486492954863181 4.8908877291459225 0.9495082207147183 1.010459750900306 0.19946469668293065 0.045403289524842114 0.2870637330668809 16.75159716145684 0.012099745442882186 0.024819277714907117 3.262173422578842e-06 5.486492954863181 0.06095153018558763 VDIDAPDVDVHGPDWHLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VDIDAPDVDVHGPDWHLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ; 118.47 4.1725e-05 25152000.0 44559.0 46030.0 51766.0 51272.0 55548.0 57529.0 53504.0 50298.0 48906.0 38917.0 False True 52101.95861963376 50599.55419832771 53000.29776364824 48399.39606606681 44663.76815465449 54512.0779659835 48435.71378458491 48977.73079513618 49621.15772893803 45972.3440331975 1.1333326528229657 1.1006520390126031 1.1528735129402086 1.0527937411918062 0.9715355850117614 1.1857580706917903 1.0535837317672678 1.065373798642254 1.0793697552838648 1.0 15.48847860756744 -5.4998332188123475 0.01188062304918541 1.663203981498597e-07 2.2037825040403383 0.23593061599506993 0.05499317093679129 5502.808703384498 13.137462982952165 1138.4666160876814 1301.099308549693 3.163492296155167e-06 5.4998332188123475 2.20378233771994 VDIDAPDVDVHGPDWHLK ddPTM_PC-9_Lapatinib_30min_R1 2 VDIDAPDVDVHGPDWHLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ; 119.0 3.9402e-05 24205000.0 95473.0 80609.0 86680.0 75877.0 82102.0 86579.0 69146.0 71112.0 92673.0 69940.0 False True 94111.53751239601 80422.35481310205 79553.50499447594 81457.24769825199 77272.92177874257 82876.21799550642 72726.04154602367 74416.12312711946 82235.19085004689 82029.03581080813 1.147295425115748 0.9804132648662148 0.96982128594024 0.9930294424784547 0.9420191401123492 1.010327833020642 0.8865890087231929 0.9071924641263966 1.0025131959336233 1.0 16.323847050323074 VDIDAPDVEVHDPDWHLK ddPTM_PC-9_AZD4547_30min_R2 4 VDIDAPDVEVHDPDWHLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ;;; 140.03 1.7985e-05 9762500.0 72795.0 78111.0 84853.0 113540.0 107629.0 101736.0 86922.0 106805.0 83096.0 105058.0 False True 95942.29576993815 103358.8532061423 83727.79377803479 87365.1071755135 92686.57116177266 95374.43183727012 94657.88960977382 90300.74138473856 87488.2849161538 101379.95139716622 0.9463635999791961 1.0195196563196556 0.8258811789130049 0.8617592134489378 0.9142495126937242 0.9407622564705238 0.9336943676264151 0.8907159664239359 0.8629742242961785 1.0 16.629412851830715 -4.46758629776035 0.0017018959413039163 1.8235923674601697 1.599394295970843e-05 0.013197185907097952 0.05793118636673491 3252029.524617718 773.2326599862167 408545.2468931614 420030.9864174855 3.407326117988294e-05 4.46758629776035 -1.82357637351721 VDIDAPDVEVHDPDWHLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VDIDAPDVEVHDPDWHLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ; 142.45 1.8809000000000002e-05 4928300.0 34692.0 36246.0 35933.0 40289.0 47687.0 41386.0 39566.0 37966.0 37631.0 32217.0 False True 40564.67040176699 39844.26333853111 36789.77899666135 38031.73794870038 38343.07467399378 39215.64530411085 35818.022046966296 36969.43272830212 38181.28218414237 38057.687070368316 1.065873244655233 1.046943900317942 0.9666845735695231 0.9993181634601189 1.0074988162863863 1.0304263953718857 0.9411507846164981 0.9714051371526067 1.0032475729159664 1.0 15.21590026503146 -5.13242323243277 4.901898220180384 0.9897448104745469 1.061388823048355 0.5599517891236196 0.023752499854593632 0.1617779895953151 5.630920082530531 0.0064142521302854435 0.01845413851484146 7.371854715682523e-06 5.13242323243277 0.07164401257380815 VDIDAPDVEVHDPDWHLK ddPTM_PC-9_Lapatinib_30min_R1 2 VDIDAPDVEVHDPDWHLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ; 121.95 2.6411999999999997e-05 4563100.0 55364.0 47653.0 49976.0 43538.0 48915.0 47125.0 42873.0 35071.2 47667.0 40193.0 False True 54574.49920748587 47542.66240629158 45867.16619293882 46739.92975851038 46037.915870590135 45109.57360374043 45092.754160799894 36700.73598571021 42298.2405042373 47140.30649619392 1.1577035293966995 1.0085352841337623 0.9729925323383739 0.9915067005829529 0.9766146911731939 0.9569215169906149 0.95656472162396 0.7785425830583729 0.8972839518481373 1.0 15.524673518262722 -1.522878745280439 0.41098424406748546 0.9046549169086651 4.965619044748631 0.5654167057411486 0.05912035207335177 57.34854672971379 0.7469081773309928 0.0432661264207871 190.18553949850903 0.029999999999992987 1.522878745280439 4.0609641278399655 VDIDAPDVSIEGPDAK ddPTM_PC-9_Lapatinib_30min_R1 2 VDIDAPDVSIEGPDAK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ; 140.91 0.00010267 5694200.0 40920.0 42635.0 45678.0 39705.0 46239.0 36407.0 42062.0 43407.0 43813.0 42201.0 False True 40336.47329619105 42536.281276986585 41922.53116217904 42625.0381519972 43519.31292937169 34849.957478862154 44239.76454905336 45423.84768504424 38878.318568656505 49495.38662070216 0.8149542017986731 0.8593989092954205 0.8469987613884874 0.8611921446062342 0.8792599856401387 0.7041051673346392 0.8938159204225601 0.9177390214797324 0.7854937848368092 1.0 15.595006439901127 -11.12521118564266 2.8499527073899436 1.011565535087389 0.8426877525976969 0.40619550132843774 0.05785326636520377 48163746.23691476 47071507.01683948 4156073.3662240966 0.01524414613387222 7.495296447372361e-12 11.12521118564266 -0.16887778248969199 VDIDT(ph)PDIDIHGPEGK ddPTM_PC-9_AZD4547_30min_R2 10 VDIDTPDIDIHGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VDIDT(1)PDIDIHGPEGK;VDIDT(1)PDIDIHGPEGK;VDIDT(1)PDIDIHGPEGK;VDIDT(1)PDIDIHGPEGK;VDIDT(1)PDIDIHGPEGK;VDIDT(1)PDIDIHGPEGK;VDIDT(1)PDIDIHGPEGK;VDIDT(1)PDIDIHGPEGK;VDIDT(1)PDIDIHGPEGK;VDIDT(1)PDIDIHGPEGK 194.32 6.8187e-40 79183400.0 389210.8 520298.7 515502.0 648469.0 548954.0 628500.0 837167.0 1281507.0 1092707.0 799394.0 True False 512971.7383124419 688475.0797793729 508666.1066569768 498974.4907961775 472741.2127357843 589199.7956448487 911673.2411926251 1083479.5392512747 1150465.2612144474 771407.4593765951 0.6649815633452582 0.892492121265922 0.6594000362247598 0.646836486646653 0.6128294547706671 0.763798416106845 1.1818309897202504 1.4045489528022939 1.491384672562259 1.0 19.55713357108224 -7.318089171982002 3.0001253902340435 1.3314458487344214 0.6994490217375705 0.7991919587820793 0.13898125572951436 0.10846805959279976 1.937377421810956 0.06298103741641192 0.041128724339329584 4.8074062972800986e-08 7.318089171982002 -0.6319968269968509 VDIDT(ph)PDIDIHGPEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VDIDTPDIDIHGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VDIDT(1)PDIDIHGPEGK;VDIDT(1)PDIDIHGPEGK;VDIDT(1)PDIDIHGPEGK;VDIDT(1)PDIDIHGPEGK 139.9 4.1122e-05 26604600.0 163132.0 194050.0 150412.0 159963.0 266221.0 191110.0 236832.0 300269.0 214366.0 206871.0 True False 190747.02559613288 213314.00156822687 153998.39252068644 151000.79171704318 214056.9061334385 181087.8551700726 214397.55844480416 292387.256911303 217500.69720937157 244375.07471006498 0.7805502497439305 0.8728959032393544 0.6301722575569356 0.6179058641565459 0.8759359209911363 0.7410242447390409 0.8773298942176195 1.1964692277156388 0.8900281563797859 1.0 17.898737617915927 -7.533819614114173 5.848854276440721 1.0352156594756965 0.7561374746654681 0.5759655486248281 0.10599362859857486 0.11374951698912247 14.260306633908929 0.04968718199450697 0.02952006213773221 2.9253671880669935e-08 7.533819614114173 -0.2790781848102284 VDIDT(ph)PDIDIHGPEGK ddPTM_PC-9_Lapatinib_30min_R1 6 VDIDTPDIDIHGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VDIDT(1)PDIDIHGPEGK;VDIDT(1)PDIDIHGPEGK;VDIDT(1)PDIDIHGPEGK;VDIDT(1)PDIDIHGPEGK;VDIDT(1)PDIDIHGPEGK;VDIDT(1)PDIDIHGPEGK 185.96 1.2988e-07 38434100.0 390265.4 600837.0 445239.0 448793.0 811201.0 614873.0 888539.0 677778.0 758344.0 930652.0 True False 384700.1438300915 599445.7988418152 408633.168092242 481798.7343495606 763487.752062528 588576.3151289698 934543.2017652822 709270.0402302385 672931.3130036572 1091513.9581841563 0.35244638050261773 0.5491874788656426 0.37437282870119637 0.441404098167541 0.6994759401269288 0.5392293068868547 0.8561898771500726 0.6498039121828371 0.6165118713856361 1.0 20.057899148827687 -7.220729993664329 0.12301082920391655 1.2639309356578292 6.107565600967707e-21 0.6999529777897316 0.10695907772350129 6.17236687759053 0.46996321131401153 1.7801250475521293 2.6246278868767705 6.01547610957611e-08 7.220729993664329 -1.2639309356578292 VDIDT(ph)PDINIEGSEGK ddPTM_PC-9_AZD4547_30min_R2 11 VDIDTPDINIEGSEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(0.994)PDINIEGS(0.006)EGK;VDIDT(1)PDINIEGSEGK 231.37 5.6433e-29 28563000.0 178151.0 221205.19999999998 266637.2 382665.39999999997 317465.2 319755.7 424680.0 617495.0 527656.0 427048.0 True False 234799.31222900315 292705.45499654795 263101.41651034873 294447.8041514947 273390.63682823733 299761.325531067 462475.69728582783 522075.3363734767 555546.8189289266 412097.17950329446 0.5697668508966974 0.7102825972974366 0.638445079453026 0.7145106028301287 0.6634130259220853 0.7274044580755753 1.1222491205672778 1.2668743256208164 1.3480966300194863 1.0 18.652625063921434 -7.290767076759009 2.8865023688747864 1.2285620567979296 0.6645438617956834 0.8853923499048457 0.09100921805696188 0.07849062090958414 1.3106945428808214 0.039682472131850145 0.02633218673231253 5.1195633720337024e-08 7.290767076759009 -0.5640181950022463 VDIDT(ph)PDINIEGSEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 9 VDIDTPDINIEGSEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK 212.92 1.7639000000000003e-21 18238100.0 142039.3 149019.9 125774.0 163423.0 249585.0 194079.0 203403.0 292462.0 206222.0 189518.7 True False 166083.74808594811 163813.61083379018 128772.92916055152 154266.9391345149 200680.61091091385 183901.15558344696 184135.1953298052 284785.1823891028 209237.60661630583 223876.94008079608 0.7418528591020107 0.7317127470773482 0.5751951456638544 0.6890702502850036 0.8963880372783781 0.8214385792349937 0.8224839738445224 1.2720612595755743 0.9346099090902038 1.0 17.772346408860514 -7.0774795127132615 0.9936659394190284 1.0655960377127258 0.6878474774084765 0.5941775655734068 0.11722263872847134 0.3654535235213872 0.7326649051788762 0.07950707536130071 0.053247464579289375 8.366050605987004e-08 7.0774795127132615 -0.3777485603042493 VDIDT(ph)PDINIEGSEGK ddPTM_PC-9_Lapatinib_30min_R1 8 VDIDTPDINIEGSEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK 217.65 9.2201e-22 26235900.0 211616.4 243738.0 193330.6 187387.7 288356.0 240785.0 292688.0 225325.0 266641.0 304251.0 True False 208598.7113303052 243173.63963621794 177435.70434569704 201168.81656504216 271395.4670097084 230487.1868472496 307841.95250661735 235794.42208935402 236609.0827257923 356840.3799610258 0.5845714864250745 0.6814633468969443 0.49724110361354457 0.5637501467379165 0.7605514461097432 0.6459111686643296 0.8626881087287261 0.6607840237001977 0.6630670070232377 1.0 18.444919353913875 -6.262703808865601 24.879455526711556 0.7474194325565587 0.5828416171266183 0.397967769655159 0.10936287642793079 120.05881170858297 2362327.6418059627 0.03197469853584031 0.03829853364188584 5.461301977933682e-07 6.262703808865601 -0.16457781542994043 VDIDVPDVNIEGPDAK ddPTM_PC-9_Lapatinib_30min_R1 1 VDIDVPDVNIEGPDAK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 124.62 0.00015985 1110300.0 9883.1 15846.0 14152.0 11976.0 14434.0 9338.4 13472.0 12957.0 12096.0 10794.0 False True 9742.165181661425 15809.309560575346 12988.477188299776 12856.754990764848 13585.02049833585 8939.018400873634 14169.51424099773 13559.029521854034 10733.621103473142 12659.728517899077 0.7695398181633495 1.2487874078992456 1.0259680663717152 1.0155632462881967 1.0730894014929737 0.7060987436053718 1.119258933630688 1.071036357745229 0.8478555514280824 1.0 13.627958846710632 VDIDVPDVNIEGPEGK ddPTM_PC-9_AZD4547_30min_R2 1 VDIDVPDVNIEGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 82.515 0.029026999999999997 1906000.0 19461.0 20860.0 20783.0 26077.0 24214.0 25491.0 25120.0 28378.0 22023.0 27556.0 False True 25649.193186053544 27602.587060466863 20507.40384062904 20065.350535633817 20852.304064064152 23897.04374030681 27355.63133611189 23992.832161566537 23187.09081915442 26591.272827393615 0.9645718485363527 1.038031809896344 0.7712080566336359 0.7545840571784527 0.7841784859046939 0.898679950201132 1.0287447131124483 0.9022822005289557 0.8719812311980681 1.0 14.698665214955614 -7.003056828918331 24.672112721966435 0.9456236683852792 0.8592202535334593 0.16861188736082955 0.09195991705385002 223.39723647996283 1803086.627638823 0.0366569571970252 0.031721498085309316 9.929861042913442e-08 7.003056828918331 -0.0864034148518199 VDIDVPDVNIEGPEGK ddPTM_PC-9_Lapatinib_30min_R1 1 VDIDVPDVNIEGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 275.82 1.1415999999999998e-81 4175900.0 35325.0 41702.0 41166.0 32482.0 41680.0 32275.0 39120.0 38338.0 37603.0 37628.0 False True 34821.25902218837 41605.44158116324 37781.49038535536 34870.83463677553 39228.46434603286 30894.67348669971 41145.44218436994 40119.323439749955 33367.75416285557 44131.9496638416 0.7890260749281669 0.9427510431348926 0.8561029066955244 0.7901494246773798 0.8888903536970566 0.7000523140724163 0.9323277692868714 0.9090766155890164 0.7560906421996261 1.0 15.429535863736755 -11.630393335835372 2.3641080262150793 1.2791776746034331 0.844492701104309 0.2805339164685745 0.07639006648186528 16367990.076639682 4264602.586393058 24583322.40097526 0.018819162035171116 2.3421066336903176e-12 11.630393335835372 -0.43468497349912416 VDIEAPDVSLEGPEGK ddPTM_PC-9_Lapatinib_30min_R1 1 VDIEAPDVSLEGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 204.48 3.2075e-16 2537300.0 17097.0 17744.0 18756.0 18172.0 17690.0 14111.0 16755.0 17126.0 18379.0 22220.0 False True 16853.193644794184 17702.9148581881 17213.954080253716 19508.429500014936 16649.50897987815 13507.505424347624 17622.491917155377 17921.736481536795 16308.963480550014 26060.69739371107 0.6466900478596238 0.6792955150333062 0.6605331323331264 0.7485766480187396 0.6388742683415672 0.5183094381659654 0.6762095292740712 0.6876921292928118 0.6258068705592533 1.0 14.669588071014447 -10.969160759668794 3.176567167959067 1.0060101884223385 0.6545721583744905 0.7783863639291584 0.05545471346073719 17086602.21375499 21921603.58330273 919810.4516364041 0.015657589852680488 1.0735919349652414e-11 10.969160759668794 -0.351438030047848 VDIEGPDVNIEGPEGK ddPTM_PC-9_AZD4547_30min_R2 1 VDIEGPDVNIEGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 111.12 0.0049907 0.0 5802.3 4505.8 6740.1 9180.3 8869.4 6838.9 6432.6 8026.2 8601.2 7166.7 False True 7647.3107046625755 5962.2117342786005 6650.721870096897 7063.923669221124 7638.036906988124 6411.262501886327 7005.088938402597 6785.935213727719 9055.841872302179 6915.796014373705 1.1057744746618465 0.8621150366330663 0.961671202602581 1.0214187426204522 1.1044335158401613 0.9270462125489588 1.012911445601245 0.9812225808314641 1.3094431723377367 1.0 12.75567960109868 -8.213130839105212 24.991591750215093 1.1547220609072364 0.993979150969551 0.29085955116983875 0.09836766709056416 387.59337256234534 200515.2534310293 0.06251289599502026 0.02362757759252034 6.1216593782731474e-09 8.213130839105212 -0.16074290993768536 VDIEGPDVNIEGPEGK ddPTM_PC-9_Lapatinib_30min_R1 2 VDIEGPDVNIEGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ; 156.08 8.8146e-05 8618500.0 45921.0 51214.0 51498.0 47276.0 52200.0 43091.0 47953.0 45435.0 49922.0 49892.0 False True 45266.15811911995 51095.41712957879 47264.03322802873 50752.83474811281 49129.69862914859 41248.098380027135 50435.771704169005 47546.07596862222 44299.258658034596 58515.76572308885 0.7735720033696674 0.8731906093714129 0.8077145132423609 0.8673360780800141 0.8395976370136304 0.7049057270347173 0.8619176572488791 0.8125344576984957 0.7570482605947549 1.0 15.836537757513282 -10.651757796630141 4.27026190872097 1.0000347449170235 0.8135484561863906 0.5517969292338654 0.051085348896588605 35820531.29257125 1.0808403486882365 12515.613833571535 0.012153640634220914 2.229678280501427e-11 10.651757796630141 -0.1864862887306329 VDIETPNLEGTLT(ph)GPR ddPTM_PC-9_AZD4547_30min_R2 1 VDIETPNLEGTLTGPR 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VDIET(0.056)PNLEGT(0.216)LT(0.728)GPR 79.393 0.021897999999999997 4600400.0 10968.0 10005.0 13755.0 17085.0 20055.0 13306.0 12640.0 13752.0 13540.0 13779.0 True False 14455.595851427746 13238.920591561406 13572.599712642665 13146.317210618705 17270.70942449849 12473.973716547895 13764.93551307541 11626.944389522272 14255.696757542137 13296.60140400119 1.0871647131633044 0.99566198830158 1.020757056653471 0.988697548432394 1.2988814885660496 0.9381324849516995 1.0352220913333003 0.8744297912114228 1.072130864451749 1.0 13.698769921203866 -10.38175356059023 4.894776569294396 0.9999999173838563 1.0319122509025909 0.0088868453879688 0.10623337535122641 9.531915697477332e-08 2.2049329873273403e-08 0.10201139368830078 0.024741332979492152 4.1518957417573195e-11 10.38175356059023 0.03191233351873457 VDIETPNLEGTLT(ph)GPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VDIETPNLEGTLTGPR 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VDIET(0.012)PNLEGT(0.039)LT(0.948)GPR;VDIET(0.169)PNLEGT(0.295)LT(0.536)GPR 126.91 6.4667e-05 5727800.0 12745.8 15536.3 16907.8 16480.699999999997 26695.0 21466.0 19498.0 18300.6 16569.0 16619.9 True False 14903.412198975024 17078.641188170306 17310.946075188567 15557.3398101503 21464.306381660917 20340.285171266703 17651.008286704473 17820.228641088503 16811.290279531615 19632.956306943986 0.759101786097483 0.8698965617383744 0.8817289563806472 0.7924094347751296 1.0932793842193393 1.0360276289145787 0.899049944936794 0.9076691437848136 0.8562791062487938 1.0 14.260989807994813 -6.230141774056709 24.999617518587886 0.9609831560043308 0.8329311137251872 0.4664282265122205 0.0728956743646631 730.3122044219756 583352.0787840226 0.023252273391600315 0.030015550695168453 5.886514605835903e-07 6.230141774056709 -0.12805204227914357 VDIETPNLEGTLT(ph)GPR ddPTM_PC-9_Lapatinib_30min_R1 2 VDIETPNLEGTLTGPR 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VDIET(0.009)PNLEGT(0.157)LT(0.833)GPR;VDIET(0.418)PNLEGT(0.08)LT(0.502)GPR 97.291 0.0053992 6361200.0 32476.0 32495.0 29532.0 23580.0 29008.7 22192.8 23426.7 21481.5 24357.0 26356.0 True False 32012.88628463099 32419.75982398685 27103.99295681666 25314.151860574097 27302.465299298547 21243.665677943565 24639.61989827657 22479.608912071286 21613.658169419257 30911.599482837486 1.0356269756408092 1.04878946306181 0.8768227270758067 0.8189208026789049 0.8832433699995765 0.6872392898898136 0.7970994807938295 0.7272224436186892 0.699208663771004 1.0 14.915860686164075 -5.410624410132957 1.1298062511938318 0.7766386384162451 1.0866934263566195 0.5220513812260823 0.08902354855919517 0.5122396392871866 1.0415720632016765 0.028935369637350987 0.1465559377422874 3.884861943472265e-06 5.410624410132957 0.31005478794037433 VDIETPNLEGTLTGPR ddPTM_PC-9_Lapatinib_30min_R1 2 VDIETPNLEGTLTGPR 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ; 136.99 1.5591999999999998e-06 2887400.0 10069.1 12775.2 11070.0 10679.8 13045.8 11461.400000000001 9329.3 10546.099999999999 10929.6 9923.2 False True 9925.512787553205 12745.619809305948 10159.867331435735 11465.228118768413 12278.47169302964 10971.222639828347 9812.325505384519 11036.110306430883 9698.593354209668 11638.411898167138 0.8528236390324279 1.0951339341506874 0.872959938205637 0.9851196382363818 1.0549954581830276 0.9426735138628439 0.8430983188462166 0.9482488163328273 0.8333261822205348 1.0 13.506606590463253 -7.003701079674055 24.984221465808474 0.9005743235084298 0.9766990156010343 0.12489602807257116 0.08143654024317222 275.5958142705421 1860427.7032190536 0.027314670873957246 0.023578820307198368 9.915141588567554e-08 7.003701079674055 0.07612469209260453 VDILDPALLR ddPTM_PC-9_Lapatinib_30min_R1 1 VDILDPALLR 10 0 E9PM69;P17980;E9PKD5;R4GNH3 E9PM69 PSMC3 26S protease regulatory subunit 6A 0 102.07 0.015477000000000001 2653100.0 30749.0 29521.0 33572.0 26685.0 27560.0 25124.0 24625.0 20238.0 24832.0 28608.0 False True 30310.513621324 29452.64593826482 30811.839751667616 28647.503918550425 25938.97498504474 24049.50508690451 25899.96200894961 21178.331362451336 22035.158667447507 33552.85468223613 0.9033661638743149 0.8777985127404947 0.9183075491928354 0.853802282692723 0.7730780355561697 0.7167647973523108 0.7719153036078868 0.6311931298550215 0.6567297738488275 1.0 15.034147895921311 -6.251391655798207 2.2116414570035676 0.7333078968214114 0.8976870691798554 0.3045730959789903 0.09509361989468494 0.3318969395452289 3.1888523131260555 0.03062220903498926 0.03962501885997641 5.605422393726596e-07 6.251391655798207 0.16437917235844401 VDINAPDVDVQGPDWHLK ddPTM_PC-9_Lapatinib_30min_R1 1 VDINAPDVDVQGPDWHLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 121.26 5.8753000000000005e-05 4000500.0 40723.0 34289.0 38036.0 36120.0 43251.0 36857.0 30493.0 29398.0 36621.0 35287.0 False True 40142.282552316414 34209.605927209894 34908.826903205954 38776.385292787796 40707.061214737674 35280.7120278634 32071.77833660511 30763.938402675412 32496.357343773983 41386.310933028035 0.9699410661963873 0.8265922996270048 0.8434872815723043 0.9369374660026195 0.9835875751431546 0.8524729852089304 0.7749368719648426 0.7433360864769535 0.7851957956909976 1.0 15.336866035804961 -6.997537479960475 24.926476850858336 0.8057965786835191 0.9062357418560572 0.19081735742626615 0.08016090891590923 104.77032580665202 1060504.7376388274 0.028075062713624657 0.024611950384448356 1.005686267728821e-07 6.997537479960475 0.10043916317253809 VDINAPDVDVR ddPTM_PC-9_Lapatinib_30min_R1 1 VDINAPDVDVR 11 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 126.03 0.0019879999999999997 5821800.0 23424.0 23102.0 26050.0 21342.0 26491.0 25979.0 24800.0 18683.0 23851.0 22590.0 False True 23089.9694645645 23048.508738382654 23908.26955590795 22911.561874824925 24932.851463309893 24867.938730006867 26084.022652668053 19551.080385644756 21164.649217835475 26494.65140071706 0.8714954998026351 0.8699306282534769 0.902380982271044 0.864761778832268 0.9410522556501764 0.9386022240448815 0.9845014474114616 0.7379255567452236 0.7988272386653357 1.0 14.693413525018439 -10.890601085575431 4.342996090989708 1.0002128661514589 0.8813996384771964 0.2230893909201529 0.06768325656810813 0.00015017990399873236 2.186390773167756e-05 0.07055042165719895 0.017080411944358363 1.2864677823318687e-11 10.890601085575431 -0.1188132276742625 VDINT(ph)PDVDVHGPDWHLK ddPTM_PC-9_AZD4547_30min_R2 4 VDINTPDVDVHGPDWHLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VDINT(1)PDVDVHGPDWHLK;VDINT(1)PDVDVHGPDWHLK;VDINT(1)PDVDVHGPDWHLK;VDINT(1)PDVDVHGPDWHLK 151.01 0.00064216 249505000.0 194813.5 277707.0 327362.0 550639.0 409694.0 394838.0 521151.0 848368.0 708898.0 586697.0 True False 256760.14062747298 367470.3568936274 323020.965985469 423697.68583774526 352815.0599332076 370148.71744283417 567532.4293967374 717272.2191572296 746368.9010360496 566156.9166066673 0.4535140931711957 0.6490609689909066 0.5705502423630815 0.7483750059563532 0.6231753946376722 0.6537917432173522 1.002429561045221 1.2669141683480454 1.3183074853337577 1.0 19.110842441690316 -7.396179453414919 2.5379953414689758 1.2178538358550652 0.6164708934406018 0.864333645787826 0.10484345319144515 0.09580763946103212 1.2012271693481613 0.051580891505448784 0.03103979054714971 4.0162482246668535e-08 7.396179453414919 -0.6013829424144634 VDINT(ph)PDVDVHGPDWHLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 VDINTPDVDVHGPDWHLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VDINT(1)PDVDVHGPDWHLK;VDINT(1)PDVDVHGPDWHLK;VDINT(1)PDVDVHGPDWHLK;VDINT(1)PDVDVHGPDWHLK;VDINT(1)PDVDVHGPDWHLK 140.51 0.00067923 215444000.0 514484.0 486209.0 488062.0 544634.0 865828.0 729136.0 737820.0 1041793.0 772135.0 729321.0 True False 601575.9796778129 534476.6162766612 499699.24906544125 514119.92270725075 696175.2187983043 690898.8245894301 667928.3482457852 1014447.0376209269 783426.0136390947 861541.1239981386 0.698255675696698 0.6203727267206063 0.5800062645257092 0.596744494704308 0.808058024633318 0.8019336574244863 0.7752715797780401 1.1774795298374157 0.9093309556756426 1.0 19.716560136786242 -7.102604377422268 0.9522479351793982 1.0285228538773115 0.623047088124147 0.7219318912809497 0.09540678051274494 0.28611809252530285 0.5242894798650433 0.06619042685729462 0.04354079385575739 7.895790608234599e-08 7.102604377422268 -0.40547576575316446 VDINT(ph)PDVDVHGPDWHLK ddPTM_PC-9_Lapatinib_30min_R1 7 VDINTPDVDVHGPDWHLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VDINT(1)PDVDVHGPDWHLK;VDINT(1)PDVDVHGPDWHLK;VDINT(1)PDVDVHGPDWHLK;VDINT(1)PDVDVHGPDWHLK;VDINT(1)PDVDVHGPDWHLK;VDINT(1)PDVDVHGPDWHLK;VDINT(1)PDVDVHGPDWHLK 121.35 0.00016738 332307000.0 411734.0 326639.0 326785.0 256764.0 470665.0 346299.0 433351.0 323726.0 432332.0 479723.0 True False 405862.59765723144 325882.68746414076 299917.9987265783 275647.2810995946 442981.4100629925 331488.5990323973 455787.79437727237 338767.4917798654 383638.21750221134 562642.4813592825 0.7213507886512798 0.5792002883906738 0.5330525309820355 0.4899155151485558 0.7873230776901132 0.5891638296339751 0.8100842177365262 0.6021008064685061 0.6818507848454377 1.0 19.101858959426075 -14.52287874528031 0.1968551947511243 2.6217209663112673 0.5801231558742228 0.5586924746890423 0.09735157267474345 103.71282067475346 1.0199610639812662 65.91730542803987 0.24276901330541173 3.0000000000001852e-15 14.52287874528031 -2.0415978104370445 VDIQTEDLEDGTCK ddPTM_PC-9_Lapatinib_30min_R1 2 VDIQTEDLEDGTCK 14 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4;H7C5L4 O75369-2 FLNB Filamin-B 0 ; 182.17 9.837700000000001e-05 13403300.0 46954.0 48497.0 50230.0 54292.0 49807.0 36676.0 51567.0 57158.0 40439.0 41988.0 False True 46284.42734969099 48384.7081761468 46100.28329340718 58284.81479280271 46877.45018432957 35107.45297593179 54236.88694073117 59813.769345537825 35884.33397845159 49245.56985450681 0.9398698702530127 0.9825190026046328 0.9361305682847777 1.1835544794181858 0.9519120262558904 0.7129058122315313 1.1013556569854084 1.2146020347059472 0.7286814648397771 1.0 15.587706324698999 -10.742524399854485 4.447203033879775 1.0000065957674815 0.9805168331534774 0.00036729918307976117 0.15814659646914353 1.027385084165409e-05 1.8028472952239607e-06 0.15211307071509808 0.03688035352919233 1.8091542641526403e-11 10.742524399854485 -0.019489762614004147 VDKGVVPLAGTNGETTTQGLDGLSER ddPTM_PC-9_Lapatinib_30min_R1 2 VDKGVVPLAGTNGETTTQGLDGLSER 26 1 P04075;J3KPS3;H3BQN4;P04075-2;H3BUH7;H3BPS8;H3BR04;H3BMQ8;H3BU78 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 ; 106.5 1.0665999999999998e-09 16004800.0 115739.0 72219.0 71697.0 73156.0 69706.0 74430.0 58433.0 51010.0 79142.0 57912.0 False True 114088.54063606687 72051.78134262229 65802.34941842353 78536.13628126218 65606.03012726885 71246.80240480429 61458.37482513514 53380.11082116038 70228.19455779361 67922.01203711043 1.6796990727208216 1.0608016338393433 0.9687926998168314 1.1562692848137734 0.9659023365124079 1.0489501159929906 0.9048373713010186 0.785902967538641 1.0339533893581239 1.0 16.051591575674898 -4.756236816524273 3.7509313692938404 0.9817259772953328 1.7731824006832073 0.8389486117408165 0.09099002950749636 0.11375402106911432 2.7374866113596132 0.024434874649012898 0.26045919053044664 1.7529243886979037e-05 4.756236816524273 0.7914564233878745 VDKLDASESLR ddPTM_PC-9_Lapatinib_30min_R1 1 VDKLDASESLR 11 1 A0A087WVQ6;Q00610-2;Q00610;J3KS13;K7EJJ5 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 95.48299999999999 0.008037 8492500.0 49248.0 44319.0 44305.0 46743.0 52874.0 53188.0 47089.0 43889.0 44917.0 40139.0 False True 48545.71448902287 44216.382078451235 40662.413922245774 50180.636150076956 49764.05527428358 50913.27322728379 49527.03801175347 45928.24316467179 39857.974463021135 47076.97266814443 1.031198731303984 0.9392358848165938 0.8637431767094235 1.0659274228147784 1.057078491964234 1.0814899587146831 1.0520438168545814 0.9755989088004813 0.8466554284190798 1.0 15.522733928959772 -4.396021828959375 19.32271495250944 0.9915186481710399 12.247879447619939 0.024772987750779185 0.07871700832162634 3127227.32586664 979381.3620369432 0.021200676097102522 1563823861.0952528 4.0177061613029604e-05 4.396021828959375 11.256360799448899 VDLTLDPDTAHPALMLS(ph)PDRR ddPTM_PC-9_AZD4547_30min_R2 1 VDLTLDPDTAHPALMLSPDRR 21 1 Q8WV44-3;Q8WV44;H0YAD6;D6REK2;Q8WV44-2 Q8WV44-3 TRIM41 E3 ubiquitin-protein ligase TRIM41 1 VDLTLDPDTAHPALMLS(1)PDRR 57.00899999999999 0.0055722 3087800.0 11785.0 13529.0 17881.0 22353.0 21598.0 16320.0 16981.0 25101.0 16642.0 14656.0 True False 15532.384856772054 17901.984675985444 17643.886256762155 17199.861200407362 18599.49050861722 15299.507820085815 18492.276103444103 21222.2172135979 17521.66214468364 14142.89790093921 1.0982462692982158 1.2657932484117416 1.247543917826802 1.2161482972499678 1.3151117005081436 1.0817802636523168 1.307530905827727 1.500556488652058 1.2389018337974462 1.0 13.787790140358709 VDLTLDPDTAHPALMLS(ph)PDRR ddPTM_PC-9_Lapatinib_30min_R1 1 VDLTLDPDTAHPALMLSPDRR 21 1 Q8WV44-3;Q8WV44;H0YAD6;D6REK2;Q8WV44-2 Q8WV44-3 TRIM41 E3 ubiquitin-protein ligase TRIM41 1 VDLTLDPDT(0.005)AHPALMLS(0.995)PDRR 45.43600000000001 0.027416000000000003 2353200.0 5023.9 4834.6 6304.8 6064.3 5195.3 4883.5 4222.5 2912.1 6710.3 4296.9 True False 4952.258264729572 4823.405780736942 5786.4436812318 6510.288851911763 4889.722668352795 4674.644088994513 4441.120389148822 3047.4067971437166 5954.515351408389 5039.613439740644 0.9826662945371525 0.9570983644700278 1.1481919695669338 1.291823059398541 0.9702574863766609 0.9275798917694542 0.8812422703153553 0.6046905846216147 1.181542081075732 1.0 12.29909736164974 -6.508436445094691 16.311181928962363 0.8982704422213366 1.0941703584158406 0.2113057523787758 0.15847292300050042 10.327942757338405 11664.434146480255 0.05086115850091367 0.055199317077496056 3.1014412220240754e-07 6.508436445094691 0.1958999161945041 VDLTLLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 VDLTLLSPK 9 0 E7EVA0;P27816-4;B5MEG9 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 VDLTLLS(1)PK;VDLT(0.063)LLS(0.937)PK 105.25 0.0026486 9145900.0 74544.0 57837.0 50419.0 73875.0 63809.0 64610.0 66081.0 65864.0 55610.0 64248.0 True False 98247.44138847827 76531.67918582076 49750.41111681066 56844.26010737238 54950.22177351403 60569.926486258846 71962.08098414064 55686.23220415171 58549.4310699349 61998.69707556926 1.5846694531132803 1.2344078633223126 0.802442849019402 0.9168621727338202 0.8863125253509125 0.9769548287834354 1.16070311762241 0.8981839108050387 0.9443655081746298 1.0 15.9199502766237 -4.936756564633775 3.10291539715544 0.9507528874031519 1.5942108109895599 0.8291024438644671 0.09048353062222281 0.11239302998030261 1.9634578538569094 0.024719480030768317 0.1482677009434356 1.1567604601893967e-05 4.936756564633775 0.643457923586408 VDLTLLS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VDLTLLSPK 9 0 E7EVA0;P27816-4;B5MEG9 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 VDLT(0.001)LLS(0.999)PK 102.95 0.0030111 2952000.0 20919.0 20316.0 16744.0 21662.0 21375.0 18211.0 22690.0 21927.0 19163.0 17153.0 True False 24460.173530916738 22332.838216233467 17143.240461973608 20448.348369151554 17186.722191721372 17255.983101366717 20540.638938625732 21351.439483576913 19443.222622165777 20262.703116926714 1.2071525398051957 1.1021648043383432 0.8460490371421757 1.0091619193724335 0.8481949369017907 0.8516130844828746 1.0137166211287398 1.053731052583044 0.9595571977720794 1.0 14.306539027195495 -5.046357435556272 4.7061176374898315 0.9475620477112484 1.1883998951145542 0.5831923506352381 0.07239094528256983 0.1313415178943166 6.53537526711634 0.01963640383501533 0.06266841171061403 8.987575763915952e-06 5.046357435556272 0.24083784740330583 VDLTLLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 VDLTLLSPK 9 0 E7EVA0;P27816-4;B5MEG9 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 VDLT(0.001)LLS(0.999)PK;VDLT(0.001)LLS(0.999)PK 93.62299999999999 0.0061133 5865200.0 64598.0 63715.0 52890.0 58732.0 57519.0 63498.0 61060.0 55687.0 59526.0 61188.0 True False 63676.82067417766 63567.47183213796 48541.58836130407 63051.347204208505 54135.84550670494 60782.33856106759 64221.38803112546 58274.42131538831 52821.555043431115 71764.2642721149 0.887305420323528 0.8857816975744859 0.6764033443894114 0.8785897527651247 0.7543565875828292 0.8469722246520054 0.8948937006810458 0.8120256217554748 0.7360425913814563 1.0 16.130977998087708 -6.94977312875845 24.999759511520157 0.8487705048842106 0.8144706894853033 0.048237952715654675 0.08731161865887123 460.90360412504157 229406.68640581582 0.030338609530525383 0.026756128408848157 1.1226047390238763e-07 6.94977312875845 -0.03429981539890725 VDLVDENFTELR ddPTM_PC-9_Lapatinib_30min_R1 1 VDLVDENFTELR 12 0 D6RDM7;P61086-3;P61086 D6RDM7 UBE2K Ubiquitin-conjugating enzyme E2 K 0 147.62 0.00063729 1024200.0 4136.4 4581.6 5130.9 4138.2 6735.9 5345.4 5591.0 4553.1 5037.6 3702.9 False True 4077.4141774771424 4570.991586692667 4709.057207846762 4442.537032630521 6339.707605288933 5116.789702736003 5880.474623026894 4764.653647908745 4470.212439720267 4342.941331195892 0.9388600643044761 1.0525105540474748 1.0843013636912415 1.0229327761623719 1.459772794937389 1.1781853155559485 1.3540304080984715 1.0971029273832553 1.029305279260894 1.0 12.084456748215015 VDLYQQAS(ph)PPDALR ddPTM_PC-9_AZD4547_30min_R2 4 VDLYQQASPPDALR 14 0 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 VDLYQQAS(1)PPDALR;VDLYQQAS(1)PPDALR;VDLYQQAS(1)PPDALR;VDLYQQAS(1)PPDALR 137.17 6.692e-05 25607900.0 36860.8 33330.3 42649.5 51383.8 52639.3 43118.5 41900.7 54055.7 35561.5 40280.8 True False 48581.76764773048 44103.66766545922 42083.93976331175 39538.05878179625 45331.24181545767 40422.293378699156 45629.781127588525 45702.633641412045 37441.20828975888 38870.58145252131 1.2498338288834436 1.1346284520937742 1.0826681307743082 1.0171717865885344 1.166209511705601 1.0399199566405557 1.1738898524922574 1.1757640851664588 0.9632273789238694 1.0 15.2463910681989 -1.5228854551844777 0.015306329740322549 0.02203361691094466 2.4099050443260337 0.2742996366733832 0.07557725186120057 8603.510835215795 10.204028970794086 633.7181179563048 995.9194819203055 0.02999953649982312 1.5228854551844777 2.387871427415089 VDLYQQAS(ph)PPDALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VDLYQQASPPDALR 14 0 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 VDLYQQAS(1)PPDALR;VDLYQQAS(1)PPDALR;VDLYQQAS(1)PPDALR;VDLYQQAS(1)PPDALR 130.47 1.9363e-05 19338300.0 36099.2 42915.7 43649.4 49245.0 52825.4 43944.3 43386.9 41548.0 39401.9 30782.5 True False 42210.08156830009 47176.08707601941 44690.167237271344 46485.96230444412 42474.642080306825 41639.783548481115 39276.97873804587 40457.40902374486 39978.07824642871 36363.12357586409 1.160793612249441 1.2973606895347238 1.2289969299264023 1.2783819906851739 1.168069128926516 1.1451101955421505 1.0801321469565899 1.1125944375856187 1.0994126553243637 1.0 15.150188511255726 -6.780524366371089 1.4147365267612027 1.0789211470083224 1.2451001357047675 0.7268736158733844 0.04548320733680131 0.2113333423736958 0.8824728450326514 0.020203451025291263 0.01797079129564183 1.6575843344052815e-07 6.780524366371089 0.1661789886964451 VDLYQQAS(ph)PPDALR ddPTM_PC-9_Lapatinib_30min_R1 4 VDLYQQASPPDALR 14 0 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 VDLYQQAS(1)PPDALR;VDLYQQAS(1)PPDALR;VDLYQQAS(1)PPDALR;VDLYQQAS(1)PPDALR 130.87 1.8128e-05 20811400.0 79210.0 81061.0 93080.0 72161.0 81268.0 88300.0 71272.0 64403.3 84700.0 65344.0 True False 78080.45087466517 80873.30823487283 85427.32169919038 77467.96066203942 76487.97601903544 84523.61483735337 74962.11542342564 67395.71243380585 75160.19406945888 76638.62333459304 1.018813327762652 1.055255231840371 1.1146771429625917 1.0108214016818338 0.9980343160014776 1.1028853489230308 0.9781245038308164 0.8793961778197138 0.9807090837386321 1.0 16.225784025615795 -7.481948354957947 8.021481644112917 0.9437798398301301 1.0485566185580462 0.4868793342564822 0.045719246002258795 0.2262015031092686 40.87301355356962 0.019213086122843493 0.012717003914468235 3.2964891074051034e-08 7.481948354957947 0.10477677872791602 VDNDENEHQLSLR ddPTM_PC-9_AZD4547_30min_R2 5 VDNDENEHQLSLR 13 0 P06748;P06748-3;P06748-2;E5RGW4 P06748 NPM1 Nucleophosmin 0 ;;;; 231.07 3.5212e-20 388962100.0 202011.0 202734.0 285581.7 309396.0 287307.0 303572.0 263834.0 329374.0 274509.0 289709.0 False True 266246.29591017205 268263.8008205507 281794.70006223203 238069.53232054895 247419.38232981288 284589.5948504339 287314.7148858176 278476.8165615547 289018.98531876924 279566.37609055726 0.9523544985393002 0.9595710491795858 1.0079706436905451 0.8515671149360013 0.8850112298542966 1.0179678930997391 1.0277155604461907 0.9961026803572056 1.0338116813631053 1.0 18.09283133027025 -6.7828589460996795 24.900079836784776 1.0156632689174325 0.9326962487635273 0.5119045704115446 0.04091286627881217 212.66517269598523 247219.77215761895 0.01567850127990475 0.013839550351459284 1.6486977828345098e-07 6.7828589460996795 -0.08296702015390522 VDNDENEHQLSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 VDNDENEHQLSLR 13 0 P06748;P06748-3;P06748-2;E5RGW4 P06748 NPM1 Nucleophosmin 0 ;;;;; 214.61 1.9411000000000002e-14 493143100.0 545675.0 537991.0 634351.0 678212.0 734572.0 577172.0 657989.0 618645.0 555289.0 479418.6 False True 638046.9999274805 591399.1910213456 649476.3336295628 640213.9804329714 590637.8897692248 546904.0842667631 595659.5184921741 602406.2242585594 563409.0511214207 566333.3971044512 1.1266278894899833 1.0442597841572663 1.146809170976327 1.1304542230888321 1.0429155207675154 0.9656928005005068 1.0517824333469674 1.063695390980898 0.9948363525831567 1.0 19.11129208357766 -6.393396201224408 4.915546892922935 1.0199049653571184 1.109203459843988 0.6087098889481964 0.03657701337667008 0.1725305429256909 6.168226491875233 0.011836141663607922 0.013426148184022811 4.042069706640472e-07 6.393396201224408 0.08929849448686955 VDNDENEHQLSLR ddPTM_PC-9_Lapatinib_30min_R1 5 VDNDENEHQLSLR 13 0 P06748;P06748-3;P06748-2;E5RGW4 P06748 NPM1 Nucleophosmin 0 ;;;; 265.77 1.6597000000000002e-55 827823000.0 1353320.0 1351121.0 1819226.0 1568225.0 1915423.0 1518731.0 1551411.0 1630156.0 1794825.0 1416591.0 False True 1334021.4086315066 1347992.5623371257 1669656.2606954416 1683557.4979452395 1802761.5850065066 1453778.4154648778 1631735.4704676776 1705898.9989370592 1592672.9081548608 1661446.8668611418 0.8029275177194094 0.8113365460093203 1.00494111126756 1.013308057889248 1.0850552135996627 0.8750074675643418 0.982117155242168 1.026755072920206 0.9586059836892582 1.0 20.66400872564534 -5.258422109077426 24.125617155478743 0.9935576167008813 0.8071319917825451 0.6850189005220246 0.0504747906567451 87.22955792524465 697457.6548689761 0.013250976317076585 0.032004243804259744 5.515411126734275e-06 5.258422109077426 -0.18642562491833614 VDNEFDQR ddPTM_PC-9_AZD4547_30min_R2 1 VDNEFDQR 8 0 Q14204;A0A2R8Y706;A0A2R8Y5T0;A0A2R8Y542;A0A2R8Y6I5 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 106.68 0.01761 8307000.0 64588.0 67698.0 74200.0 129790.0 98079.0 85248.0 91684.0 106960.0 73694.0 82464.0 False True 85125.64048614292 89580.05459345577 73216.05951858134 99868.92073551065 84462.42381677343 79917.42908374239 99843.69838455738 90431.78969628451 77589.31439071712 79576.96046008826 1.0697272174505534 1.1257033954995623 0.9200660479524445 1.2549979310355766 1.0613929374587694 1.0042784823859274 1.2546809755900878 1.1364066832087723 0.9750223424232439 1.0 16.280063174121388 VDNEFDQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VDNEFDQR 8 0 Q14204;A0A2R8Y706;A0A2R8Y5T0;A0A2R8Y542;A0A2R8Y6I5 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 96.03399999999999 0.028769 6721500.0 52217.0 54790.0 56908.0 69036.0 70137.0 56759.0 64017.0 59553.0 57689.0 39165.0 False True 61056.30676723932 60229.1891055046 58264.902544791825 65168.13673773182 56394.15833266722 53782.458121491036 57952.84631705613 57989.79685161928 58532.592488134476 46265.30447003058 1.3196996640709444 1.301821954819717 1.2593649433893654 1.4085746864574507 1.2189298001745095 1.1624792863155125 1.2526200136561605 1.2534186798486002 1.2651509194335966 1.0 15.497643064760158 -14.412472863325203 0.17092510421989857 7.86562571310718e-15 1.3324061024565956 0.6802953415633555 0.05761083400742663 79.60003043593954 0.7761572228500114 27.097685489109832 0.21814933120170082 3.8683622514712035e-15 14.412472863325203 1.3324061024565879 VDNEFDQR ddPTM_PC-9_Lapatinib_30min_R1 2 VDNEFDQR 8 0 Q14204;A0A2R8Y706;A0A2R8Y5T0;A0A2R8Y542;A0A2R8Y6I5 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 ; 96.03399999999999 0.028769 14588900.0 161029.0 153204.0 158794.0 129303.0 147180.0 148597.0 134622.0 132483.0 150583.0 99406.0 False True 158732.696930898 152849.26555082607 145738.57028256642 138812.37396216352 138523.16176701314 142241.85270652574 141592.06844949524 138638.64383296954 133622.7568307122 116588.1946498307 1.3614817298410626 1.3110183754873679 1.2500285360819596 1.1906211806356768 1.188140550448212 1.2200364979811642 1.2144631699183863 1.1891310629636795 1.1461088082892468 1.0 16.83106218765451 -1.5228787455237296 0.026691131142627788 5.729991149174208e-14 2.89537742254744 0.8810297458732268 0.0316616499880489 650.2670490931054 1.33835486019611 48.69964097504603 106.9736798944424 0.029999999983187073 1.5228787455237296 2.8953774225473827 VDNLTYRT(ph)SPDTLR ddPTM_PC-9_Lapatinib_30min_R1 1 VDNLTYRTSPDTLR 14 1 J3QL05;J3KP15;Q01130-2;Q01130 J3QL05 SRSF2 Serine/arginine-rich splicing factor 2 1 VDNLT(0.001)Y(0.001)RT(0.639)S(0.284)PDT(0.075)LR 65.565 0.027852 95300000.0 74348.0 39613.0 71447.0 56274.0 35032.0 44400.0 22284.0 22598.0 56893.0 34280.0 True False 73287.78388624644 39521.278532315446 65572.90345339551 60412.57768456092 32971.48663556197 42501.11550145519 23437.75648355061 23647.985578054933 50485.111230150265 40205.25232477119 1.8228410381370124 0.9829879492626805 1.6309536605742145 1.502604117406313 0.820079087409374 1.057103563438389 0.5829526026655523 0.5881814989502001 1.2556844768026856 1.0 15.295096363737855 -6.261798997014607 24.999727504219873 0.8570120518214568 1.459435871251615 0.5312034837662971 0.27541099755624826 25.806782688186182 1794017.224905026 0.08169657321234754 0.09853231650773996 5.472691949621186e-07 6.261798997014607 0.6024238194301581 VDNLTYRTS(ph)PDTLR ddPTM_PC-9_AZD4547_30min_R2 1 VDNLTYRTSPDTLR 14 1 J3QL05;J3KP15;Q01130-2;Q01130 J3QL05 SRSF2 Serine/arginine-rich splicing factor 2 1 VDNLT(0.001)YRT(0.071)S(0.91)PDT(0.019)LR 102.58 0.0006732 161280000.0 45472.0 25348.0 66740.0 141630.0 102610.0 57623.0 43785.0 63068.0 51090.0 72990.0 True False 59931.15012364353 33541.24529284344 65854.9839928587 108979.3916616872 88364.37267752626 54019.8247007846 47681.78017721571 53322.2897584635 53790.51309769778 70434.642316427 0.8508760483854433 0.4762038137733376 0.934980030096636 1.5472413584795146 1.254558407218853 0.7669496560811798 0.6769648941071603 0.7570463624833018 0.7636939910341901 1.0 16.103997552808714 -6.876935039705392 22.8534212440048 0.7704542782735762 1.0086288800333731 0.14001780972248268 0.2694518984935543 9.439348986481306 1829.5846982198098 0.10833638132413455 0.09554374385100636 1.3275930197372955e-07 6.876935039705392 0.238174601759797 VDNLTYRTS(ph)PDTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VDNLTYRTSPDTLR 14 1 J3QL05;J3KP15;Q01130-2;Q01130 J3QL05 SRSF2 Serine/arginine-rich splicing factor 2 1 VDNLT(0.001)Y(0.001)RT(0.154)S(0.84)PDT(0.004)LR;VDNLT(0.01)Y(0.002)RT(0.433)S(0.45)PDT(0.104)LR;VDNLT(0.073)Y(0.003)RT(0.05)S(0.871)PDT(0.003)LR 77.633 0.0070293000000000005 122844000.0 66444.0 31909.9 42802.6 110134.0 98945.0 105607.0 88883.0 133466.0 101300.0 71498.0 True False 77691.65687118078 35077.70398681768 43823.17631376447 103963.5490392458 79557.43753262573 100068.78300950173 80463.358782806 129962.65891891626 102781.32085922828 84460.02142214347 0.9198630969185596 0.41531725183319823 0.5188629552286028 1.2309202305268294 0.9419537929665691 1.1848065075586873 0.9526798292015394 1.5387476433299014 1.216922742009646 1.0 16.36598099260882 -5.761871146892395 24.99989856942296 1.1590117048528403 0.5977446345591942 0.5922583810027285 0.20288507541217965 7.505582850279587 434633.3912446503 0.056564132203438124 0.09007687500883829 1.7303296636469092e-06 5.761871146892395 -0.5612670702936461 VDNLTYRTS(ph)PDTLR ddPTM_PC-9_Lapatinib_30min_R1 1 VDNLTYRTSPDTLR 14 1 J3QL05;J3KP15;Q01130-2;Q01130 J3QL05 SRSF2 Serine/arginine-rich splicing factor 2 1 VDNLT(0.02)Y(0.007)RT(0.234)S(0.655)PDT(0.085)LR 54.093999999999994 0.037705 113120000.0 112610.0 58576.0 90380.0 76313.0 64995.0 64053.0 42208.0 38455.0 95582.0 45834.0 True False 111004.16074985541 58440.37087089872 82949.30527688918 81925.3125927053 61172.121885086475 61313.60250483577 44393.32371466985 40241.759686879435 84816.54863691892 53756.34583003395 2.06494989634948 1.0871343646697016 1.5430607121093594 1.5240119343627931 1.1379516397654637 1.14058352661649 0.8258248031782524 0.7485955205012494 1.5777960225401235 1.0 15.714147451593472 -6.371876931637729 2.274219019693154 1.0270991165638368 1.5299089527403351 0.37673024475567707 0.3032235743339844 0.34350581394227336 3.4854430983605114 0.10209497475144325 0.12116965327417491 4.2473990772549284e-07 6.371876931637729 0.5028098361764983 VDRDYVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VDRDYVLK 8 1 Q9BUP3-3;Q9BUP3 Q9BUP3-3 HTATIP2 Oxidoreductase HTATIP2 0 71.692 0.045001 4532700.0 27486.0 26977.0 25745.0 25648.0 28527.0 21032.0 30077.0 27240.0 20880.0 25014.0 False True 32138.836926754495 29655.098275218057 26358.85843845621 24211.025711937906 22937.339132782963 19929.044895280043 27227.8888213771 26524.978863165732 21185.330498920895 29548.840189284943 1.0876513839757658 1.0035960154528043 0.8920437577111574 0.8193562101539726 0.7762517576273787 0.6744442342784998 0.9214537236304295 0.8976656509443734 0.7169597981921185 1.0 14.850813884368343 -5.215898643503263 1.7561711737528025 0.8202838306609445 1.0922615944532004 0.475272348203407 0.09112126057952252 0.3851084649793486 1.9903919754163084 0.02614534900755014 0.13029743211397393 6.0827694557930205e-06 5.215898643503263 0.2719777637922559 VDS(ph)LVSLSEEDLESDQR ddPTM_PC-9_AZD4547_30min_R2 4 VDSLVSLSEEDLESDQR 17 0 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36;H0YMW2;H0YLH1 Q12802-2 AKAP13 A-kinase anchor protein 13 1 VDS(0.993)LVS(0.006)LSEEDLESDQR;VDS(0.616)LVS(0.383)LS(0.001)EEDLESDQR;VDS(0.544)LVS(0.413)LS(0.04)EEDLES(0.002)DQR;VDS(0.952)LVS(0.046)LS(0.003)EEDLESDQR 166.48 4.654399999999999e-24 1853010.0 5488.45 7593.1500000000015 7604.19 9238.25 12823.4 11226.3 8134.76 10288.5 11080.6 7752.300000000001 True False 7233.662933148117 10047.487245358772 7503.35347211052 7108.5141920397 11043.092257996215 10524.317686313067 8858.737880881745 8698.64873121 11666.297894506763 7480.8943366164785 0.9669516247197549 1.3430863735342016 1.0030021992670197 0.9502225097935013 1.4761727356505983 1.406826137725278 1.184181660944091 1.1627819268390172 1.5594790368050158 1.0 12.868995038447965 -6.2553281277736685 24.991441390387585 1.3061057113315937 1.0811340537883658 0.275638515514806 0.1836497838570626 712.1236842834583 2912166.9570862753 0.054120234750492026 0.06811468797740211 5.554844068165349e-07 6.2553281277736685 -0.2249716575432279 VDS(ph)LVSLSEEDLESDQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VDSLVSLSEEDLESDQR 17 0 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36;H0YMW2;H0YLH1 Q12802-2 AKAP13 A-kinase anchor protein 13 1 VDS(0.568)LVS(0.397)LS(0.036)EEDLESDQR;VDS(1)LVSLSEEDLESDQR;VDS(1)LVSLSEEDLESDQR;VDS(0.999)LVS(0.001)LSEEDLESDQR 238.12 1.66e-37 910560.0 5802.8 13565.500000000002 10973.460000000001 10127.75 12323.500000000002 8188.53 12145.3 7290.82 6496.68 4593.950000000001 True False 6785.099429475767 14912.193188733756 11235.108903478804 9560.325002108511 9908.798639984958 7759.109071716786 10994.809259642616 7099.443700262337 6591.681654488957 5426.796769311812 1.2502954722471034 2.747881268202497 2.0703021286908374 1.7616884155624801 1.8259019198984159 1.4297769755436671 2.0260219291456716 1.3082199319512455 1.2146542306069936 1.0 12.405885166182635 -7.753911169287157 0.5041558647781699 0.9636576258384213 2.0594238271855385 0.4015970236387565 0.3869442984232579 0.8485440609262818 0.5005240770606009 0.38809510640037953 0.26341912280121116 1.7623364783372097e-08 7.753911169287157 1.0957662013471172 VDS(ph)LVSLSEEDLESDQR ddPTM_PC-9_Lapatinib_30min_R1 3 VDSLVSLSEEDLESDQR 17 0 Q12802-2;Q12802;Q12802-4;A8MYJ1;A0A087WTD7;A0A087WY36;H0YMW2;H0YLH1 Q12802-2 AKAP13 A-kinase anchor protein 13 1 VDS(0.508)LVS(0.492)LSEEDLESDQR;VDS(0.972)LVS(0.028)LSEEDLESDQR;VDS(0.968)LVS(0.031)LS(0.001)EEDLESDQR 204.9 3.1764000000000004e-17 3243850.0 6393.6 9971.7 6893.199999999999 9853.5 7063.5 7951.3 8206.8 10214.400000000001 6624.7300000000005 6934.4 True False 6302.426091557357 9948.611141309419 6326.467704521488 10578.159260312414 6648.038817375312 7611.241434385605 8631.707947819195 10688.998313500495 5878.5831459004385 8133.001800492801 0.7749200413524409 1.2232397564090796 0.7778760978680898 1.300646368930037 0.8174151414761139 0.9358465202755051 1.0613188290818005 1.3142746768914793 0.7228060794901384 1.0 12.989572217944303 -7.28334989144226 22.9520520522383 1.0507894546866854 0.9822276815904284 0.007256992516082472 0.21288863130140395 1490.444882796347 1561280.7288765043 0.08392956376142972 0.05666392778027564 5.207749771774162e-08 7.28334989144226 -0.068561773096257 VDS(ph)PSHGLVTSSLCIPS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 1 VDSPSHGLVTSSLCIPSPAR 20 0 Q9UER7-3;Q9UER7 Q9UER7-3 DAXX Death domain-associated protein 6 2 VDS(0.846)PS(0.154)HGLVT(0.007)S(0.029)S(0.032)LCIPS(0.931)PAR 57.745 0.041134 2903500.0 6546.7 9123.7 11109.0 16048.0 13220.0 9062.5 10629.0 14816.0 12049.0 11367.0 True False 8628.414420180705 12072.75760132223 10961.687401508345 12348.381539128419 11384.631193810526 8495.820442373017 11574.960408898613 12526.527637809906 12685.885541478974 10969.044789845531 0.7866149318825246 1.1006206859961452 0.9993292589757681 1.1257481189756644 1.0378872009301776 0.7745269168959841 1.0552386858347047 1.1419889222629664 1.1565168877077419 1.0 13.42115027749163 -7.517467862958515 24.42583924592351 1.1092745515563565 0.9819805131438637 0.1999772999095908 0.11602536479321357 304.17774320477247 1373146.9463614547 0.05350463249079675 0.032102179845317796 3.037610861586477e-08 7.517467862958515 -0.12729403841249276 VDS(ph)PSHGLVTSSLCIPS(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 1 VDSPSHGLVTSSLCIPSPAR 20 0 Q9UER7-3;Q9UER7 Q9UER7-3 DAXX Death domain-associated protein 6 2 VDS(0.926)PS(0.074)HGLVTS(0.001)S(0.012)LCIPS(0.986)PAR 79.873 0.0034208 1896300.0 7953.9 10785.0 9665.4 8741.7 10988.0 10939.0 8538.6 10360.0 10855.0 8552.6 True False 7840.475927433384 10760.027995128428 8870.748121522944 9384.593779456343 10341.707443239175 10471.164470054464 8980.686928309327 10841.36342103943 9632.395591782488 10030.905514376847 0.7816319190920482 1.0726876032982828 0.8843417086133348 0.9355679570509189 1.0309844338994987 1.0438902504910064 0.8953017168228443 1.0807960862058754 0.9602717898176597 1.0 13.292164226988481 -4.7459392461417185 24.923537894444685 0.9869502070648288 0.7816313363771928 0.46959515514187655 0.06617346038133846 758.4734132806643 1219522.7028678681 0.01600318531171829 0.3843942899223788 1.794984711347666e-05 4.7459392461417185 -0.205318870687636 VDS(ph)PSHGLVTSSLCIPSPAR ddPTM_PC-9_AZD4547_30min_R2 2 VDSPSHGLVTSSLCIPSPAR 20 0 Q9UER7-3;Q9UER7 Q9UER7-3 DAXX Death domain-associated protein 6 1 VDS(0.884)PS(0.104)HGLVT(0.006)S(0.006)S(0.001)LCIPSPAR;VDS(0.497)PS(0.497)HGLVT(0.003)S(0.003)SLCIPSPAR 62.916000000000004 0.0091491 29250000.0 19270.8 19917.5 26858.0 32376.0 27876.0 31160.0 20530.9 27359.0 24735.0 22983.0 True False 25398.513542459325 26355.442367058913 26501.845371294563 24912.21340421371 24005.89857478534 29211.560274134405 22358.11032637656 23131.29519727602 26042.441602496674 22178.37216548075 1.1451928641539584 1.1883398010643682 1.1949409620126688 1.123266090871539 1.0824012869686181 1.3171192212023737 1.0081042088911991 1.0429663198311028 1.1742269183772698 1.0 14.436865858891636 -8.712539842937305 0.27021230717936795 0.9716151430518198 1.1905767293151859 0.2531080298852989 0.08033649155627914 4.1421265296878484 0.8421737214133231 0.3070847829531609 0.152407202957579 1.9384747887180904e-09 8.712539842937305 0.21896158626336604 VDS(ph)PSHGLVTSSLCIPSPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VDSPSHGLVTSSLCIPSPAR 20 0 Q9UER7-3;Q9UER7 Q9UER7-3 DAXX Death domain-associated protein 6 1 VDS(0.5)PS(0.5)HGLVTSSLCIPSPAR;VDS(0.5)PS(0.5)HGLVTSSLCIPSPAR 127.91 2.4877e-05 12331400.0 20729.2 22698.0 26606.0 26568.0 29827.0 22635.0 28429.0 25101.0 22489.0 19182.4 True False 24238.244139637605 24951.307434143877 27240.38794381688 25079.481094618153 23982.61346491105 21447.980753359825 25735.999311863838 24442.125346707886 22817.859079991966 22660.01727220516 1.0696480875753038 1.1011159936205883 1.2021344739763289 1.1067723732664896 1.0583669543062613 0.9465121096649814 1.1357449115200668 1.0786454861483563 1.0069656525805217 1.0 14.46786134037757 -6.252109777965399 4.0660287486587885 1.0412238351869856 1.1258314360088097 0.33816485870786883 0.05661603014706686 0.2725850423316926 10.803952127855213 0.018130247492767995 0.022475946812333152 5.596161277083378e-07 6.252109777965399 0.08460760082182417 VDS(ph)PSHGLVTSSLCIPSPAR ddPTM_PC-9_Lapatinib_30min_R1 1 VDSPSHGLVTSSLCIPSPAR 20 0 Q9UER7-3;Q9UER7 Q9UER7-3 DAXX Death domain-associated protein 6 1 VDS(0.81)PS(0.188)HGLVT(0.002)SSLCIPSPAR 109.13 8.925e-05 13401000.0 10569.0 21384.0 27632.0 17448.0 23867.0 23986.0 22720.0 22436.0 27919.0 16908.0 True False 10418.284121882773 21334.48666182905 25360.203622604553 18731.184124821735 22463.189984327382 22960.17469409694 23896.33043018622 23478.458466644854 24774.468219896407 19830.525271506154 0.5253660192679047 1.0758407238200538 1.2788467917712607 0.9445631857132888 1.1327581935816908 1.1578197944704811 1.205027607842647 1.1839554497520193 1.2493097323798097 1.0 14.275435271768785 -4.767818762574732 4.291053507473421 1.1476735376879066 0.4706558179394427 0.7802662412304637 0.09783981798551367 0.09296463654838033 3.531992148769069 0.024040377285626528 0.1959610735089378 1.706794510661178e-05 4.767818762574732 -0.6770177197484639 VDS(ph)PTVNTTLR ddPTM_PC-9_Lapatinib_30min_R1 1 VDSPTVNTTLR 11 0 Q9H0B6;Q9H0B6-2;A8MZ87 Q9H0B6 KLC2 Kinesin light chain 2 1 VDS(0.499)PT(0.499)VNT(0.001)TLR 141.34 0.00013014 10931000.0 22555.0 30377.0 31701.0 28132.0 31955.0 33493.0 26356.0 31241.0 32110.0 23705.0 True False 22233.36156391957 30306.663922857315 29094.66614939878 30200.921125600922 30075.469725947216 32060.58246599638 27720.58471910156 32692.57091087767 28493.433666709883 27802.377665072952 0.7996928115918114 1.090074535636943 1.0464812218542474 1.0862711631869229 1.0817589088335369 1.1531597351931826 0.9970580593157633 1.1758911883262444 1.024856003682918 1.0 14.76292064735175 -4.7599768629729455 24.99904691999415 1.078352287733437 0.799692471058037 0.6767185420221201 0.05652182978142581 19.577545200603264 334527.40000168484 0.012782977850657608 0.07816804141103258 1.7378934125088118e-05 4.7599768629729455 -0.2786598166754001 VDS(ph)PTVTTTLK ddPTM_PC-9_AZD4547_30min_R2 4 VDSPTVTTTLK 11 0 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;G3V3H3;H0YJT3;F8W6L3;E7EVH7;G5E9S8;H0YJU9;H0YJL0;G3V2E7;Q07866-8;Q07866-2;Q07866-3;Q07866-5;Q07866-10;Q07866 Q07866-6 KLC1 Kinesin light chain 1 1 VDS(0.665)PT(0.334)VT(0.001)TTLK;VDS(0.979)PT(0.021)VTTTLK;VDS(0.974)PT(0.025)VTTTLK;VDS(0.575)PT(0.401)VT(0.013)T(0.004)T(0.008)LK 153.49 0.00042626 129206000.0 424928.0 406194.0 430567.0 452430.0 398311.0 470000.0 413888.0 474570.0 395444.0 400639.0 True False 560046.2649485318 537488.2669433986 424857.40025252034 348129.25347382 343012.39299832523 440610.82570099994 450723.23019270116 401236.1110337109 416346.362525074 386612.75055502023 1.448597502654868 1.3902497167301955 1.098922370363099 0.9004598347417321 0.8872247294117888 1.1396696696331412 1.1658260870745834 1.037824309875185 1.0769079962504295 1.0 18.56052969310121 -5.274593433428619 3.541534258798843 1.0334515089005467 1.4351029781055018 0.7677143712895574 0.08472626547437098 0.11492172046575914 3.111880282218503 0.025395662635386722 0.06772236804929614 5.313816665962597e-06 5.274593433428619 0.4016514692049551 VDS(ph)PTVTTTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VDSPTVTTTLK 11 0 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;G3V3H3;H0YJT3;F8W6L3;E7EVH7;G5E9S8;H0YJU9;H0YJL0;G3V2E7;Q07866-8;Q07866-2;Q07866-3;Q07866-5;Q07866-10;Q07866 Q07866-6 KLC1 Kinesin light chain 1 1 VDS(0.98)PT(0.019)VTTTLK;VDS(1)PTVTTTLK;VDS(0.987)PT(0.013)VTTTLK;VDS(0.91)PT(0.09)VTTTLK 210.15 2.3928e-06 104447800.0 314751.0 347850.0 309192.0 320857.0 352984.0 252160.0 337225.0 248316.0 245939.0 211695.0 True False 368032.12768438197 382382.2491394373 316564.3098971902 302880.4225224291 283819.31911684555 238936.28569769 305280.60670242715 241797.96811254954 249535.39260412386 250073.62772330258 1.4716950805048352 1.5290786662339677 1.2658844228366901 1.2111649888070377 1.1349430233838227 0.9554637483088155 1.2207628988379737 0.9669071077742362 0.9978476934010241 1.0 17.9319933961743 -5.597091413288816 0.8562360477029608 1.0284722514873776 1.5790033917225024 0.8343945741376952 0.07934639160430496 0.3473340668091867 0.4156165913187019 0.03297568121841006 0.14486870537393895 2.5287656684380658e-06 5.597091413288816 0.5505311402351247 VDS(ph)PTVTTTLK ddPTM_PC-9_Lapatinib_30min_R1 3 VDSPTVTTTLK 11 0 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;G3V3H3;H0YJT3;F8W6L3;E7EVH7;G5E9S8;H0YJU9;H0YJL0;G3V2E7;Q07866-8;Q07866-2;Q07866-3;Q07866-5;Q07866-10;Q07866 Q07866-6 KLC1 Kinesin light chain 1 1 VDS(0.908)PT(0.092)VTTTLK;VDS(0.997)PT(0.003)VTTTLK;VDS(0.865)PT(0.134)VT(0.001)TTLK 153.49 0.00042626 81475000.0 193470.0 241457.0 245848.0 227609.0 282431.0 245068.0 267051.0 234679.0 228265.0 180787.0 True False 190711.08232194762 240897.9211515737 225635.32644072393 244348.12514136638 265818.9638607101 234587.0129214104 280877.59408942144 245583.04307781032 202555.39196298763 212035.79206646507 0.8994287259868231 1.1361191372636816 1.064137918611382 1.152390937209189 1.2536513824863402 1.1063557271872118 1.324670666928615 1.158215038529106 0.9552886802219425 1.0 17.693948289594765 -4.759720358303661 6.2308284277488335 1.1414841113571528 0.891294184073878 0.29474676722032056 0.10413716065893978 0.15967490493859798 26.010274815698804 0.025833609426904144 0.16955104972754387 1.7389201569483956e-05 4.759720358303661 -0.2501899272832748 VDS(ph)TTCLFPVEEK ddPTM_PC-9_AZD4547_30min_R2 1 VDSTTCLFPVEEK 13 0 A0A6I8PRN4;A0A6I8PTT9;Q06210-2;Q06210 A0A6I8PRN4 GFPT1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 1 VDS(0.864)T(0.124)T(0.012)CLFPVEEK 63.76 0.044170999999999995 2719900.0 10761.0 11233.0 13520.0 22295.0 14937.0 18499.0 13041.0 16138.0 12661.0 13075.0 True False 14182.774157295216 14863.847576712573 13340.715966188935 17155.232204316304 12863.255381387886 17342.254605623006 14201.623736235475 13644.242914347762 13330.234612056218 12617.24822972026 1.124078237906687 1.1780577908977323 1.0573395817611424 1.359665110170909 1.0194976865944627 1.3744878669164065 1.1255721911520435 1.0813960909644615 1.056508865432044 1.0 13.62310967828343 -7.745809552508336 2.986151096507513 1.0431670177283858 1.1835411099161797 0.24827308009432514 0.10844755136117713 0.37090806554755085 6.718012580400985 0.061179005826769335 0.02866206813717524 1.7955208288038207e-08 7.745809552508336 0.14037409218779384 VDS(ph)TTCLFPVEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 9 VDSTTCLFPVEEK 13 0 A0A6I8PRN4;A0A6I8PTT9;Q06210-2;Q06210 A0A6I8PRN4 GFPT1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 1 VDS(0.947)T(0.042)T(0.011)CLFPVEEK;VDS(0.682)T(0.159)T(0.159)CLFPVEEK;VDS(0.95)T(0.042)T(0.008)CLFPVEEK;VDS(0.941)T(0.059)T(0.001)CLFPVEEK;VDS(0.333)T(0.333)T(0.333)CLFPVEEK;VDS(0.333)T(0.333)T(0.333)CLFPVEEK;VDS(0.867)T(0.035)T(0.099)CLFPVEEK;VDS(0.969)T(0.031)TCLFPVEEK;VDS(0.333)T(0.333)T(0.333)CLFPVEEK 241.76 8.5488e-27 461477700.0 996757.7 985159.0 822375.6 1208562.0 1162830.2 954032.0 1090480.7 1010535.6 892106.0 839711.1 True False 1165489.091748048 1082959.0748309877 841984.1531808305 1140850.1893508695 934981.9697564377 904000.8824426495 987182.4736994208 984010.1112509748 905151.3625512616 991944.0752805892 1.1749544362350959 1.091754164189804 0.8488222009317009 1.1501154326952954 0.9425752852971688 0.9113425897391813 0.9951997277872531 0.9920016014739842 0.9125024132990797 1.0 19.919899259777083 -5.0339002886924025 7.627583781868382 0.9727887066484341 1.1553551488742146 0.44672789493023723 0.07559254806860356 0.1744903744217222 35.42595512357617 0.01847454960880329 0.0522896102029752 9.249105032523415e-06 5.0339002886924025 0.18256644222578056 VDS(ph)TTCLFPVEEK ddPTM_PC-9_Lapatinib_30min_R1 3 VDSTTCLFPVEEK 13 0 A0A6I8PRN4;A0A6I8PTT9;Q06210-2;Q06210 A0A6I8PRN4 GFPT1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 1 VDS(0.928)T(0.041)T(0.031)CLFPVEEK;VDS(0.995)T(0.005)TCLFPVEEK;VDS(0.333)T(0.333)T(0.333)CLFPVEEK 236.05 6.1816e-26 160033300.0 204757.0 276317.0 269010.0 279800.0 303918.0 267814.0 256241.0 279406.0 269183.0 216765.0 True False 201837.1276321646 275677.2049633657 246893.0362086299 300377.4253854379 286042.14076577756 256360.21952492604 269507.9051831579 292388.2227817517 238864.77591734537 254232.54142879296 0.7939075245750804 1.0843505847601302 0.9711307404673105 1.181506599026661 1.1251200934318395 1.008369023430972 1.0600842192290452 1.1500818154061747 0.9395523270739442 1.0 17.955789179654644 -4.758854081798963 24.990031629241685 1.0642774713281156 0.7939071651409312 0.5234422869414319 0.07531097192169021 53.69468768244615 518918.3921806873 0.01813673996926461 0.12037418563307928 1.742392199797104e-05 4.758854081798963 -0.2703703061871844 VDSEGDFS(ph)ENDDAAGDFR ddPTM_PC-9_AZD4547_30min_R2 1 VDSEGDFSENDDAAGDFR 18 0 O43823;M0QYL4 O43823 AKAP8 A-kinase anchor protein 8 1 VDS(0.001)EGDFS(0.999)ENDDAAGDFR 116.61 0.00011863 6201800.0 11624.0 13304.0 13074.0 13196.0 18232.0 11643.0 9086.1 14379.0 14664.0 13697.0 True False 15320.190205780096 17604.257826100253 12900.630217600157 10153.866076167658 15700.801507227945 10914.961369439898 9894.745297891963 12157.055946548922 15439.109102850673 13217.472199042335 1.1590862439559444 1.3318929339133212 0.9760285494328382 0.768215429036677 1.1878823174952877 0.8257979441962235 0.748611016455089 0.9197716298150985 1.16808334228759 1.0 13.690158671780244 -5.337367388386428 5.98657506069374 0.9350503829790431 1.244163533425951 0.39577211779218835 0.14595480285078039 0.19806689095710342 12.166627404020945 0.038605110616836476 0.08232832732558142 4.598673873825216e-06 5.337367388386428 0.309113150446908 VDSEGDFS(ph)ENDDAAGDFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VDSEGDFSENDDAAGDFR 18 0 O43823;M0QYL4 O43823 AKAP8 A-kinase anchor protein 8 1 VDSEGDFS(1)ENDDAAGDFR 175.77 2.1836e-08 6990200.0 19059.0 22612.0 21027.0 17690.0 20350.0 19789.0 14263.0 17785.0 15988.0 15359.0 True False 22285.312267591293 24856.769922498086 21528.36342534156 16698.886651753815 16362.563583697303 18751.230003456476 12911.905384822338 17318.16259476515 16221.794253675642 18143.465118222895 1.2282831378890473 1.3700122749723533 1.1865629462212786 0.9203802329347673 0.9018433621735854 1.0334977294179133 0.7116559764459714 0.954512408843621 0.8940846827204375 1.0 14.147162393931323 -5.66950534654032 3.2664500300621593 0.908183777951291 1.2972691930241802 0.7718050515100846 0.08721352424958469 0.10224572576504709 2.1532568433060337 0.023890130331670794 0.04411954558819357 2.140398576453566e-06 5.66950534654032 0.3890854150728892 VDSEGDFS(ph)ENDDAAGDFR ddPTM_PC-9_Lapatinib_30min_R1 1 VDSEGDFSENDDAAGDFR 18 0 O43823;M0QYL4 O43823 AKAP8 A-kinase anchor protein 8 1 VDS(0.001)EGDFS(0.999)ENDDAAGDFR 231.4 1.2715999999999997e-35 7373100.0 11475.0 12647.0 12112.0 8676.9 9355.3 9145.3 10118.0 10769.0 11245.0 10953.0 True False 11311.364395742723 12617.716648529364 11116.198113672064 9315.028171289881 8805.039647227475 8754.176837735544 10641.860532245772 11269.367054167344 9978.469684900429 12846.211456044897 0.880521423335287 0.9822130588230343 0.8653289066358346 0.7251187015847084 0.6854191741553645 0.6814598115319197 0.8284045898402327 0.8772521838619155 0.7767636177438891 1.0 13.649055328894034 -5.540247106595181 5.9612358649412736 0.7835262614367069 0.9302738424569547 0.24831943476976115 0.09293688893637632 0.1909083086573814 23.91038263110656 0.025614661720680592 0.04684342309979458 2.8823910022077606e-06 5.540247106595181 0.14674758102024776 VDSETNIEASKLPTS(ph)EPEADAEIEPK ddPTM_PC-9_AZD4547_30min_R2 1 VDSETNIEASKLPTSEPEADAEIEPK 26 1 Q9BYW2;H7C3H4;A0A1W2PPX9 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 VDS(0.001)ET(0.001)NIEAS(0.01)KLPT(0.438)S(0.549)EPEADAEIEPK 51.479 0.038997000000000004 0.0 5819.9 6240.6 6577.5 8935.1 9261.7 8284.4 6224.5 8111.4 7293.4 6455.4 True False 7670.507138559838 8257.751908415608 6490.278052337848 6875.250740918888 7975.872823579048 7766.375158377384 6778.468441545717 6857.969511428949 7678.914234228794 6229.398410870839 1.231339951731798 1.3256098524706843 1.0418787857607166 1.103678122259925 1.2803600440229443 1.2467295629742332 1.088141742502246 1.1009039812674686 1.232689535610441 1.0 12.604877129843935 -14.522878744013967 0.14689041385015766 0.3752528820233679 1.2377947096073245 0.2839928093776526 0.08911986570853286 195.017733921242 1.7120238944308759 35.699482593329215 0.5073776809454115 3.000000008747776e-15 14.522878744013967 0.8625418275839567 VDSLLENLEK ddPTM_PC-9_Lapatinib_30min_R1 2 VDSLLENLEK 10 0 B4DY08;B2R5W2;G3V4W0;G3V576;G3V5V7;B7ZW38;P0DMR1;A0A0G2JPF8;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3;A0A0G2JNQ3;B2RXH8;O60812 B4DY08;P07910-2;A0A0G2JNQ3 HNRNPC;HNRNPCL3;HNRNPCL4;HNRNPCL2;HNRNPCL1 Heterogeneous nuclear ribonucleoprotein C-like 3;Heterogeneous nuclear ribonucleoprotein C-like 4;Heterogeneous nuclear ribonucleoproteins C1/C2;Heterogeneous nuclear ribonucleoprotein C-like 2;Heterogeneous nuclear ribonucleoprotein C-like 1 0 ; 131.82 0.00076991 11353400.0 51428.0 52439.0 79144.0 50611.0 59121.0 55008.0 49040.0 47780.0 55681.0 54596.0 False True 50694.62728925984 52317.58071734257 72637.08582467477 54333.10177334671 55643.61901635814 52655.436069911004 51579.05124543712 50000.03322946563 49409.6194330761 64032.84585540283 0.7916972393158508 0.8170428788294785 1.1343722874460678 0.8485192411413384 0.8689855694062231 0.8223191608384238 0.8055092750666037 0.7808497742295305 0.77162929076511 1.0 15.966524509616494 -6.388421235594826 2.361960493923131 0.8219956921312315 0.9100102239017286 0.061147997261449705 0.10609780326698293 0.6953974524770933 7.603520094532666 0.037021276719156566 0.04332450720879366 4.088638976573667e-07 6.388421235594826 0.08801453177049712 VDSPLPSDKAPT(ph)PPGK ddPTM_PC-9_AZD4547_30min_R2 1 VDSPLPSDKAPTPPGK 16 1 Q12893 Q12893 TMEM115 Transmembrane protein 115 1 VDSPLPS(0.005)DKAPT(0.995)PPGK 79.337 0.0064899 16723000.0 125350.0 160280.0 163940.0 99794.0 111290.0 106580.0 188990.0 121660.0 137020.0 104070.0 True False 165208.69255802932 212087.37555376944 161766.04848350707 76788.03510193045 95839.30450523242 99915.53575151614 205809.74387785792 102860.24246867959 144262.59746812584 100426.54097644285 1.645070027820459 2.1118657826073983 1.6107898062669777 0.7646189379353681 0.95432246867602 0.9949116516415061 2.049356095278985 1.0242336484815067 1.4364987190185676 1.0 16.61578107315667 -5.5316977763195085 22.48080026473994 1.1950018542452219 1.874183051503572 0.40168482304229636 0.35321486051800083 54.25983105382729 138313.91708875954 0.09856887249780802 0.17123482001636012 2.9396946613183243e-06 5.5316977763195085 0.6791811972583501 VDSPLPSDKAPT(ph)PPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VDSPLPSDKAPTPPGK 16 1 Q12893 Q12893 TMEM115 Transmembrane protein 115 1 VDS(0.001)PLPS(0.006)DKAPT(0.993)PPGK;VDSPLPS(0.005)DKAPT(0.994)PPGK 65.02199999999999 0.021036000000000003 15809000.0 204431.0 229990.0 136813.0 145084.0 205312.0 91638.0 154966.0 89553.0 90440.0 108951.0 True False 239037.1306037015 252821.88724904132 140075.14078619197 136955.41384867468 165082.5874445243 86832.3419605208 140286.49862331743 87202.3286392468 91762.5139043297 128702.9538443585 1.8572777349987706 1.9643829430269395 1.0883599529159675 1.064120206707112 1.2826635482209676 0.6746724870474056 1.0900021672615765 0.6775472204367684 0.7129790821685322 1.0 16.973685639477203 -5.1416965169611615 0.7954921004864351 0.8472389706164798 2.357582770071323 0.7658465353693087 0.20856319220501052 0.7609506495721766 0.5233552140164068 0.08384803924241374 0.9270147348764327 7.2161156196454334e-06 5.1416965169611615 1.5103437994548432 VDSPLPSDKAPT(ph)PPGK ddPTM_PC-9_Lapatinib_30min_R1 1 VDSPLPSDKAPTPPGK 16 1 Q12893 Q12893 TMEM115 Transmembrane protein 115 1 VDS(0.002)PLPS(0.001)DKAPT(0.997)PPGK 76.358 0.0083167 11387000.0 41840.0 119390.0 50818.0 42189.0 60112.0 58912.0 57706.0 54492.0 58388.0 29923.0 True False 41243.35392748371 119113.55979029946 46639.94020315278 45291.719798378304 56576.33034473911 56392.47109057945 60693.734322373464 57023.89725282633 51811.72858710237 35095.15068010876 1.1751866889934635 3.3940176201554446 1.3289568301978363 1.29054068498554 1.6120839844920642 1.6068451053136976 1.7294051498907932 1.6248369403681278 1.4763215881124065 1.0 15.098984077512801 -1.5228787455887973 0.06785918991064417 0.3223790054735155 4.714931334815649 0.13855033733718958 0.5837255244962286 505.14840115466626 2.547722019331112 29.766746078329728 213.29902898679768 0.029999999978692356 1.5228787455887973 4.392552329342133 VDSPS(ph)HGLVTSSLCIPSPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VDSPSHGLVTSSLCIPSPAR 20 0 Q9UER7-3;Q9UER7 Q9UER7-3 DAXX Death domain-associated protein 6 1 VDS(0.042)PS(0.355)HGLVT(0.292)S(0.292)S(0.018)LCIPS(0.001)PAR 69.314 0.0046964 9935800.0 10219.0 11698.0 10776.0 11696.0 19861.0 12333.0 15406.0 10602.0 12783.0 7555.9 True False 11948.874865549886 12859.300130611302 11032.94070820757 11040.711038943615 15969.37962338144 11686.235768994335 13946.632150218946 10323.708733747537 12969.92719193994 8925.724857528514 1.3387007841129517 1.440700933074916 1.2360834424446434 1.2369539970337746 1.7891409244944254 1.309275824151966 1.5625209574385979 1.156624128407888 1.4530951154068223 1.0 13.123753619730772 -10.134472171045124 7.649951033522352 1.0003605007984144 1.3911954898395682 0.3104403152133097 0.17502454171813409 0.0 0.0 0.16546891045414894 0.04013210562107804 7.337157283422425e-11 10.134472171045124 0.39083498904115377 VDSPS(ph)HGLVTSSLCIPSPAR ddPTM_PC-9_Lapatinib_30min_R1 1 VDSPSHGLVTSSLCIPSPAR 20 0 Q9UER7-3;Q9UER7 Q9UER7-3 DAXX Death domain-associated protein 6 1 VDS(0.246)PS(0.752)HGLVTSS(0.001)LCIPSPAR 74.133 0.0025661 10689000.0 10171.0 15577.0 22324.0 15926.0 15261.0 17627.0 14894.0 16219.0 17877.0 11568.0 True False 10025.959674867036 15540.932413548031 20488.606893132008 17097.251167578586 14363.377984280403 16873.134300543945 15665.13844309831 16972.59395037052 15863.504006844367 13567.513386608896 0.7389681063268848 1.1454517840304395 1.5101224748636854 1.2601609948992962 1.0586595771084348 1.2436423550683715 1.1546064482648504 1.2509730756648767 1.1692270760905685 1.0 13.72786871168911 -4.781151339697034 4.5273224151499365 1.2176814518933177 0.708261067052637 0.5320793574206235 0.12994895371048643 0.13991180192244823 6.27091933902756 0.0326044916554617 0.22306775968398276 1.6551930736416145e-05 4.781151339697034 -0.5094203848406806 VDSPSHGLVTSSLCIPS(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 1 VDSPSHGLVTSSLCIPSPAR 20 0 Q9UER7-3;Q9UER7 Q9UER7-3 DAXX Death domain-associated protein 6 1 VDSPSHGLVTSS(0.001)LCIPS(0.998)PAR 95.209 0.00030856 4840500.0 2700.7 3336.0 34207.0 65770.0 51347.0 30008.0 14404.0 44752.0 24880.0 42310.0 True False 3559.466421950301 4414.296760964403 33753.39282954326 50607.7426363706 44218.35536373595 28131.595016246007 15685.928095754593 37836.60669865478 26195.10600647331 40828.7397781617 0.08718041363241325 0.10811738948958458 0.8267067025075591 1.2395127283218146 1.0830203333238142 0.6890145316533359 0.3841883972168207 0.9267150273125174 0.6415849754070645 1.0 15.317297417505477 -5.262416744021797 6.738303898210311 0.8471991367353602 0.09330328446019362 0.6342379574696473 0.22824886256950438 0.0865901369193527 24.91416896441677 0.06533670266904135 0.15437001512572582 5.464913043955851e-06 5.262416744021797 -0.7538958522751665 VDSPT(ph)VNTTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VDSPTVNTTLR 11 0 Q9H0B6;Q9H0B6-2;A8MZ87 Q9H0B6 KLC2 Kinesin light chain 2 1 VDS(0.231)PT(0.769)VNTTLR 110.15 0.0048223 12960000.0 41490.0 51424.0 53010.0 48115.0 62449.0 45182.0 49768.0 43452.0 48393.0 31022.0 True False 48513.43753514677 56529.03487062365 54273.95944154453 45419.27254093468 50212.566743897456 42812.5763816348 45053.61475088257 42311.43104119962 49100.65607443864 36646.043029983106 1.323838360814399 1.5425685884932419 1.4810319192481054 1.2394045519122892 1.3702043274580689 1.1682728295277705 1.2294264544202096 1.154597537490779 1.3398624248262057 1.0 15.16136980685215 -6.2308242555174225 1.0071458443535204 1.185788979051407 1.4592852698633483 0.4993672470181051 0.10813558451854534 0.45303525561388003 0.9654077973200013 0.047157958603976924 0.07590956371551774 5.877271379724058e-07 6.2308242555174225 0.2734962908119414 VDSSTNSSPS(ph)PQQSESLS(ph)PAHTSDFR ddPTM_PC-9_AZD4547_30min_R2 1 VDSSTNSSPSPQQSESLSPAHTSDFR 26 0 F2Z3H6;Q9BQE9-2;Q9BQE9-3;Q9BQE9 F2Z3H6 BCL7B B-cell CLL/lymphoma 7 protein family member B 2 VDS(0.005)S(0.017)T(0.076)NS(0.103)S(0.085)PS(0.708)PQQS(0.006)ES(0.143)LS(0.853)PAHT(0.003)S(0.001)DFR 119.74 1.3713e-11 3635900.0 1160.5 2666.6 9727.0 23595.0 17022.0 8147.7 5082.9 16263.0 5184.7 11240.0 True False 1529.514860100464 3528.526301794867 9598.013624491103 18155.53728911608 14658.789121107622 7638.223030987324 5535.268253117954 13749.927036561996 5458.752657225164 10846.491021189735 0.14101471684366856 0.3253150069364856 0.8848957331675651 1.6738627500495205 1.3514775508936643 0.7042114372348873 0.51032801689544 1.2676843607485684 0.5032736067877556 1.0 13.404940767370054 -5.252178747327714 3.7932421299700896 1.0125172418743498 0.19749464215972817 0.42880034581492543 0.35136013598616983 0.21350795854538018 6.975973941892104 0.09919260300963109 0.26904940823311485 5.595272633443238e-06 5.252178747327714 -0.8150225997146217 VDST(ph)TCLFPVEEK ddPTM_PC-9_AZD4547_30min_R2 3 VDSTTCLFPVEEK 13 0 A0A6I8PRN4;A0A6I8PTT9;Q06210-2;Q06210 A0A6I8PRN4 GFPT1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 1 VDS(0.271)T(0.647)T(0.082)CLFPVEEK;VDS(0.139)T(0.431)T(0.431)CLFPVEEK;VDS(0.131)T(0.434)T(0.434)CLFPVEEK 195.94 2.6011e-06 420032100.0 354234.0 382231.0 404318.0 522597.0 493157.0 488596.0 475438.0 479790.0 453900.0 493497.0 True False 466873.0434750771 505779.6958154035 398956.4791433123 402120.33569316403 424690.66305945633 458044.0148812897 517751.06095455255 405649.4799773772 477892.227344784 476219.82023879664 0.9803729782623648 1.062071913684282 0.8377569815201281 0.8444006708740598 0.8917954377591814 0.9618331606853473 1.087210231390475 0.8518114172021809 1.0035118385142994 1.0 18.861268141170974 -6.980783798955491 16.819141478531286 0.9806032611081674 0.9223511281193075 0.11590137018774482 0.08118371040992568 14.760678524960433 12915.342818414456 0.030475527873927946 0.026841907340811877 1.0452404326766691e-07 6.980783798955491 -0.058252132988859895 VDST(ph)TCLFPVEEK ddPTM_PC-9_Lapatinib_30min_R1 1 VDSTTCLFPVEEK 13 0 A0A6I8PRN4;A0A6I8PTT9;Q06210-2;Q06210 A0A6I8PRN4 GFPT1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 1 VDS(0.068)T(0.929)T(0.003)CLFPVEEK 266.77 4.1129e-55 169010000.0 178300.0 235420.0 240100.0 227720.0 227080.0 240010.0 238690.0 213930.0 216450.0 182590.0 True False 175757.40930378452 234874.89945416155 220359.90481280215 244467.28845165158 213723.60085645737 229745.33179063638 251048.2002808606 223869.96878986168 192071.1216804533 214150.43821411827 0.8207193539714054 1.096775245537074 1.0289958155139303 1.1415680046716552 0.9980068340685153 1.0728221417923298 1.1722983262348037 1.0453864612970127 0.8968981024844368 1.0 17.70826510384269 -4.755497335953826 24.99932807034402 1.0567915791099267 0.8207189707323529 0.4587023625000993 0.07452118679778277 175.2511554981472 737242.475094333 0.018436426819473925 0.1627438728755631 1.755911665267168e-05 4.755497335953826 -0.23607260837757382 VDSTT(ph)CLFPVEEK ddPTM_PC-9_AZD4547_30min_R2 2 VDSTTCLFPVEEK 13 0 A0A6I8PRN4;A0A6I8PTT9;Q06210-2;Q06210 A0A6I8PRN4 GFPT1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 1 VDS(0.007)T(0.043)T(0.95)CLFPVEEK;VDS(0.243)T(0.324)T(0.433)CLFPVEEK 105.14 0.0055696999999999995 2675100.0 23719.0 27363.0 32727.0 36514.0 33376.0 28725.0 28627.0 31563.0 26864.0 33622.0 True False 31261.148614151592 36207.55463737079 32293.018596558068 28096.261435676402 28742.318511695925 26928.82120906648 31174.747542152654 26685.66359558548 28283.976196057025 32444.90401374034 0.963514905173169 1.1159704655633125 0.9953186664655272 0.8659683944134248 0.8858808304541022 0.8299861573842903 0.9608518961544846 0.8224916795649685 0.8717540413766929 1.0 14.985704277451969 -5.6382738133816535 4.328801717085917 0.8839530173887249 1.0432078880794717 0.4988786430323523 0.0620423528177443 0.14823807608037876 4.8491250278473155 0.016002778542765723 0.028733942302145963 2.2999912648877186e-06 5.6382738133816535 0.15925487069074684 VDVADQAQDKDRDDR ddPTM_PC-9_Lapatinib_30min_R1 1 VDVADQAQDKDRDDR 15 2 E7EX17;P23588-2;P23588;F8VP89;F8W0K0;F8VSC7 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 80.37100000000001 0.040165 12986000.0 33201.0 57357.0 49976.0 50692.0 57159.0 44135.0 52100.0 54628.0 50189.0 50330.0 False True 32727.547651682293 57224.1933905036 45867.16619293882 54420.058783554756 53797.01999891776 42247.44893371004 54797.48307274214 57166.21630931872 44536.18630639996 59029.4734394905 0.5544272334604239 0.9694173106450382 0.7770214355707576 0.9219133360445654 0.9113586292458397 0.7157009282323472 0.928307163859653 0.9684351388957966 0.754473718151201 1.0 15.849147852122258 -4.751190998643627 24.997321058538944 0.8769568616621627 0.554426569262837 0.5213358311472442 0.09428200535352864 340.84274823217714 831310.1013482063 0.022213056098194874 0.30147226881963446 1.7734093805343278e-05 4.751190998643627 -0.32253029239932574 VDVEVPDVSLEGPEGK ddPTM_PC-9_AZD4547_30min_R2 1 VDVEVPDVSLEGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 155.98 1.4373e-14 0.0 8939.9 15802.0 15574.0 18133.0 16801.0 16137.0 14005.0 21262.0 15667.0 17081.0 False True 11782.602238528349 20909.687475047827 15367.478584129178 13952.717002057294 14468.471156369942 15127.950839014997 15251.417868720026 17976.446452154054 16495.125635185577 16482.99938905177 0.7148336270857665 1.2685608354105944 0.9323229481120083 0.8464913862294309 0.8777814531729035 0.9177911423732252 0.9252817104907632 1.0906052974857388 1.000735682010755 1.0 14.008691171219798 -7.743429912239738 24.816986183136958 1.0342528698823559 0.9343129437189271 0.11224588440152306 0.13290297967603884 505.7607869171134 696938.7051912956 0.06229422403095445 0.035870316858702095 1.8053860723009042e-08 7.743429912239738 -0.09993992616342873 VDVEVPDVSLEGPEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VDVEVPDVSLEGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ; 198.37 5.020699999999999e-50 2830400.0 30133.0 36202.0 28502.0 30191.0 37858.0 31477.0 32370.0 31313.0 28303.0 25568.0 False True 35233.921746121436 39795.895309316984 29181.59577443693 28499.496150542647 30439.996665926916 29826.290707908425 29303.67926149471 30491.066928865937 28716.877830984577 30203.27600382336 1.166559605708376 1.317601948354189 0.9661731982564706 0.9435895677983728 1.0078375823229768 0.9875183971478056 0.9702152593574693 1.0095284672101843 0.9507868559473276 1.0 14.882417419766774 -5.269829355894231 24.99997848607062 0.9794870366476089 1.2420807797577598 0.8735521858440216 0.03996746583666446 155.18989512644302 462426.8811948879 0.009641688969929637 0.020605254801709744 5.372428497471861e-06 5.269829355894231 0.2625937431101508 VDVEVPDVSLEGPEGK ddPTM_PC-9_Lapatinib_30min_R1 4 VDVEVPDVSLEGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ;;; 225.13 5.8422e-28 13055500.0 88554.0 95411.0 102111.0 97018.0 93916.0 83442.0 100234.0 88080.0 91255.0 90830.0 False True 87291.20372118549 95190.08169153413 93715.82773985856 104153.02736256056 88392.04552596025 79873.3801728024 105423.62607127133 92172.51835184872 80976.90094224892 106529.8444766329 0.8194060936635708 0.8935531837035008 0.8797143016613991 0.9776887206984172 0.8297397406353001 0.7497746811253672 0.9896158826590212 0.8652271934187097 0.7601334756478597 1.0 16.700898134434482 -10.761722196747959 4.9889573484861405 1.0000211979346363 0.8670551036335079 0.22755835709684802 0.07548276828511868 1.7849663515417866e-05 2.7232496656866164e-06 0.07330096921561832 0.017775263059528323 1.73092321725278e-11 10.761722196747959 -0.13296609430112838 VDVGKDQEFTVK ddPTM_PC-9_AZD4547_30min_R2 1 VDVGKDQEFTVK 12 1 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 96.171 0.012028 0.0 17298.0 21003.0 25349.0 23876.0 24019.0 22955.0 19921.0 21563.0 18837.0 25493.0 False True 22798.404179248442 27791.809013949467 25012.855697257644 18371.757080522802 20684.37644811913 21519.620221205252 21693.930407909418 18230.933818445956 19832.685363502307 24600.497829465286 0.9267456430065255 1.1297254716797553 1.0167621757352592 0.7468042804612678 0.840811295426078 0.8747636072400978 0.8818492437956064 0.741079873457269 0.8061904072423963 1.0 14.586399890595006 -5.682220002881576 7.321012323993216 0.8341339865141377 1.0378068701535939 0.49949329292735845 0.08340665566257252 0.16660407425469081 12.976962427309829 0.02181133862408319 0.03786335657390425 2.0786434308143897e-06 5.682220002881576 0.20367288363945613 VDVGKDQEFTVK ddPTM_PC-9_Lapatinib_30min_R1 2 VDVGKDQEFTVK 12 1 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 111.52 0.0013775999999999999 19811700.0 160866.0 136419.0 142290.0 129942.0 145915.0 118317.0 142498.0 116772.0 128831.0 124817.0 False True 158572.0213407885 136103.13018705833 130591.4654552838 139498.3681538048 137332.56657992766 113256.85772039818 149875.8491919311 122197.65341714433 114320.69612942709 146391.4521418016 1.0832054674011173 0.929720473400472 0.8920702919784333 0.9529133437291145 0.9381187533197015 0.7736575876759 1.023801916021397 0.8347321624952391 0.7809246677783531 1.0 17.159471790950434 VDVS(ph)CEPLEGVEK ddPTM_PC-9_AZD4547_30min_R2 2 VDVSCEPLEGVEK 13 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0;H7C3N7 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 VDVS(1)CEPLEGVEK;VDVS(1)CEPLEGVEK 137.46 4.7349e-05 17933900.0 68672.0 71593.0 86835.0 113430.0 99377.0 99092.0 85353.0 106014.0 92695.0 82386.0 True False 90508.26753366564 94734.03717257938 85683.5111630189 87280.4659760305 85580.21892188411 92895.7615752414 92949.25164932951 89631.9722593671 97594.66845940688 79501.69121634665 1.1384445556933749 1.1915977600373455 1.0777570873284918 1.0978441419380072 1.0764578414941648 1.1684752884368923 1.169148105244557 1.1274222081069079 1.2275797780681685 1.0 16.278697930304737 -6.789862691288846 24.99909033208355 1.1484028940922144 1.1174167833049917 0.018276098485903836 0.06256553252889144 724.6661852451456 637358.3612274388 0.021370415991407033 0.01885066912899054 1.6223229380013376e-07 6.789862691288846 -0.030986110787222687 VDVS(ph)CEPLEGVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VDVSCEPLEGVEK 13 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0;H7C3N7 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 VDVS(1)CEPLEGVEK;VDVS(1)CEPLEGVEK;VDVS(1)CEPLEGVEK;VDVS(1)CEPLEGVEK 169.79 5.0645e-05 15765300.0 70845.0 75245.0 72779.0 82208.0 87650.0 71132.0 81895.0 73412.0 63163.4 56119.2 True False 82837.65924746862 82714.826323119 74514.32737589459 77602.15228193202 70475.6117007898 67401.71269927055 74137.31273154476 71485.01278644367 64087.04523158714 66293.16672065735 1.2495655788555944 1.2477127042619398 1.1240121880114602 1.1705905166505002 1.0630901371442432 1.0167218739645418 1.1183251064765192 1.0783164588842684 0.9667217362180592 1.0 16.01657254934002 -2.1263889856105 0.2498624401258315 0.9944590412768197 2.3545786486299343 0.7842628464672355 0.04319675769262063 17.207505308449644 0.30556923119887164 0.057689615057186235 9.253622242486099 0.007474996857001761 2.1263889856105 1.3601196073531145 VDVS(ph)CEPLEGVEK ddPTM_PC-9_Lapatinib_30min_R1 2 VDVSCEPLEGVEK 13 0 Q12888;Q12888-3;Q12888-2;A6NNK5;C9JXV0;H7C3N7 Q12888 TP53BP1 Tumor suppressor p53-binding protein 1 1 VDVS(1)CEPLEGVEK;VDVS(1)CEPLEGVEK 140.33 4.9634e-05 11909100.0 35541.0 47854.0 75321.0 59256.0 58239.0 57694.0 59070.0 49280.0 67005.0 41827.0 True False 35034.178822578855 47743.19700314098 69128.39812746791 63613.88391222129 54813.496522279456 55226.56211128281 62128.355568270235 51569.72870548485 59458.19130606961 49056.74121902582 0.7141562597107745 0.9732239813888126 1.4091518598601418 1.2967409234992098 1.1173489139352162 1.1257690735042982 1.2664590844076453 1.0512261398538314 1.2120289654097482 1.0 15.58216378011226 -4.961686423565636 4.0772151598162845 1.190063795239575 0.7375678598928115 0.6188293290309133 0.11551523528377367 0.13540369412010858 4.8351893898732685 0.029566462136967356 0.13464471850028015 1.0922286806978915e-05 4.961686423565636 -0.45249593534676347 VDVSAPDVEAHGPEWNLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VDVSAPDVEAHGPEWNLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 66.289 0.011842 2658200.0 12617.0 12611.0 14794.0 19062.0 18354.0 16941.0 13453.0 9662.4 12869.0 14532.0 False True 14752.808902890984 13862.93673680451 15146.745066557436 17994.017939837828 14757.665455291428 16052.584137073949 12178.634448714492 9408.77223815905 13057.184779243924 17166.5365647513 0.8593934395120496 0.8075558330892326 0.8823413511178966 1.0482031638685714 0.8596763476212146 0.9351090755275195 0.7094403931030179 0.5480879735216037 0.7606184701260438 1.0 14.067311377254283 -7.26725649788369 23.852752074752797 0.7168773505577744 0.8988461082064063 0.23252687468612576 0.12080419175668917 296.5530783372091 1215988.9752999868 0.0486329426921136 0.03382958998074666 5.4043504330031106e-08 7.26725649788369 0.18196875764863196 VDVSAPDVEAHGPEWNLK ddPTM_PC-9_Lapatinib_30min_R1 2 VDVSAPDVEAHGPEWNLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ; 163.9 1.3835999999999998e-07 5433600.0 37403.0 38952.0 39579.0 32989.0 36509.0 34270.0 32255.0 32025.0 34193.0 32027.0 False True 36869.62636112986 38861.809037203755 36324.967399358204 35415.12110807795 34361.612399455684 32804.35198727182 33925.006075072895 33512.998413010406 30341.824271747453 37562.824276704996 0.9815456391013433 1.0345816584751413 0.9670456920856597 0.942823703755445 0.9147771250194683 0.873319635009868 0.9031537624851033 0.8921852671710275 0.8077620587907782 1.0 15.197017920092069 -5.912223124847941 1.3198449625866993 0.8891585776474961 1.0093187698962969 0.4693027302002871 0.04638296383735539 0.3539131300524353 1.2495770070377314 0.01572101617217652 0.03215379129939127 1.2239871972039438e-06 5.912223124847941 0.12016019224880081 VDY(ph)VVVDQQK ddPTM_PC-9_AZD4547_30min_R2 2 VDYVVVDQQK 10 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 VDY(1)VVVDQQK;VDY(1)VVVDQQK 143.61 0.0001878 20948000.0 102299.0 145550.0 140532.0 133905.0 141374.0 168240.0 163115.0 200003.0 163166.0 157221.0 True False 134827.95404861507 192596.19111461903 138668.4538580224 103035.2710616269 121746.6603928722 157719.92620411963 177631.91900437433 169097.1319617235 171790.62165000892 151716.74064434814 0.8886821156056635 1.269445878527669 0.9139957348746812 0.6791292155633667 0.8024602945977378 1.0395683794304813 1.170812912602546 1.114558164402689 1.1323115756402757 1.0 17.211020757860055 -6.974945410407295 8.731640244006389 1.1128141344111 0.9180254800300934 0.2855652541476389 0.14535468851388275 0.3469521111227227 107.6975634132066 0.057077991930505355 0.04991941105075888 1.0593868787543252e-07 6.974945410407295 -0.19478865438100657 VDY(ph)VVVDQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VDYVVVDQQK 10 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 VDY(1)VVVDQQK;VDY(1)VVVDQQK 130.98 0.00028263 15504500.0 48277.0 58473.0 71359.0 63294.0 97735.0 61856.0 99781.0 70791.0 64013.0 65748.0 True False 56449.34258578646 64277.81300540553 73060.46919051457 59747.84238191663 78584.52834656801 58612.16246873534 90329.02132811886 68932.81125926448 64949.06902430189 77667.59193911849 0.7268069110477322 0.8276014667197504 0.94068152966278 0.7692763595496991 1.011805907516333 0.7546540455983214 1.1630207538676534 0.8875363525278218 0.836244145115426 1.0 16.245025115865936 -3.2594798780647243 0.4601870391393871 0.9434331848594563 8.232847315737453e-13 0.23688146750384576 0.11400917233283515 28.236144400920175 1.532073057737241 0.06955681629822413 19.579997827377316 0.0005501994120169336 3.2594798780647243 -0.943433184858633 VDY(ph)VVVDQQK ddPTM_PC-9_Lapatinib_30min_R1 2 VDYVVVDQQK 10 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 VDY(1)VVVDQQK;VDY(1)VVVDQQK 160.75 0.00016745 17017700.0 56493.0 93174.0 89471.0 73432.0 113346.0 124914.0 156366.0 142764.0 140721.0 114887.0 True False 55687.3994604526 92958.26132759338 82115.03974804771 78832.4342419709 106679.21112681007 119571.7194087563 164461.8663752859 149397.33662560573 124871.51912217627 134745.0648726952 0.4132796960917648 0.6898824933990625 0.6094103693194892 0.5850487683274369 0.7917114532365155 0.8873921989033556 1.2205409269027154 1.1087406931508308 0.9267242495311626 1.0 17.039872908720177 -6.674092343197614 1.7178103100713367 1.0703287390763283 0.5816839697838971 0.8198448951061077 0.10175497573774407 0.14433338861868555 0.8788991921267131 0.0416662822518515 0.04062012238700765 2.1179107600910847e-07 6.674092343197614 -0.48864476929243117 VEAEAGGS(ph)GARTPPLSR ddPTM_PC-9_Lapatinib_30min_R1 1 VEAEAGGSGARTPPLSR 17 1 Q9Y3Q8 Q9Y3Q8 TSC22D4 TSC22 domain family protein 4 1 VEAEAGGS(0.719)GART(0.281)PPLSR 52.431999999999995 0.032054 64854000.0 48746.0 35718.0 45298.0 29113.0 48297.0 35511.0 42801.0 41088.0 48595.0 31198.0 True False 48050.873101078425 35635.29716550739 41573.77329533663 31254.06713812102 45456.26541555536 33992.27731018413 45017.02635309862 42997.09847911852 43121.719371964115 36590.53273127806 1.3132050701192421 0.9738939147788325 1.1361893416708533 0.8541572042050276 1.242295807754085 0.9289910469416887 1.2302916353720503 1.1750880697717758 1.178493893178634 1.0 15.159182799959384 -7.29947562442456 24.993887128012208 1.1605590451030443 1.0705786440283251 0.053021460944876586 0.14144503552218413 1456.005097098499 956745.2338695327 0.05530171673408856 0.037285045750273374 5.017927422856181e-08 7.29947562442456 -0.08998040107471916 VEAEAGGSGART(ph)PPLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VEAEAGGSGARTPPLSR 17 1 Q9Y3Q8 Q9Y3Q8 TSC22D4 TSC22 domain family protein 4 1 VEAEAGGS(0.01)GART(0.989)PPLS(0.001)R 57.973 0.031541 72861000.0 28563.0 42795.0 44886.0 38455.0 57682.0 50837.0 54140.0 39540.0 40664.0 27565.0 True False 33398.15175503488 47043.40477769791 45956.252471102955 36300.491022792114 46379.62617370166 48171.01822657622 49011.467260343605 38502.116896093 41258.63407127007 32562.316295580047 1.0256687961589601 1.444719237743032 1.4113324142527592 1.1148006392812873 1.4243343671468836 1.479348636912383 1.5051591175347785 1.1824133316129974 1.2670669278177378 1.0 14.99091570781727 -8.684946415603022 1.3860865851896262 1.0039350173919 1.342409966336242 0.28175439286899273 0.15521272630327967 0.844492912254362 3.25076187623166 0.14878497992503575 0.04422329872963788 2.0656350035753116e-09 8.684946415603022 0.33847494894434216 VEAEAGGSGART(ph)PPLSR ddPTM_PC-9_Lapatinib_30min_R1 1 VEAEAGGSGARTPPLSR 17 1 Q9Y3Q8 Q9Y3Q8 TSC22D4 TSC22 domain family protein 4 1 VEAEAGGS(0.04)GART(0.954)PPLS(0.007)R 83.964 0.035908999999999996 9468100.0 25961.0 14228.0 19870.0 15162.0 16674.0 15552.0 14399.0 13713.0 20683.0 13843.0 True False 25590.791379335667 14195.055940165706 18236.365300418092 16277.064058949298 15693.268102345297 14886.87721348268 15144.509765151897 14350.156041767734 18353.46273835442 16235.744105361951 1.57620070957414 0.8743089228338912 1.1232232524775643 1.0025449990662085 0.9665875490832909 0.9169199216786251 0.9327881535254262 0.8838619251844767 1.1304355759273812 1.0 13.986885886287086 -4.75530723795467 24.999997357609214 0.9786855104617621 1.576201689300343 0.8179701871493498 0.08420024909309656 80.403147748365 327762.2255124601 0.020522528242990452 0.18443296909512272 1.756680425573228e-05 4.75530723795467 0.5975161788385809 VEAEAGGSGARTPPLS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 VEAEAGGSGARTPPLSR 17 1 Q9Y3Q8 Q9Y3Q8 TSC22D4 TSC22 domain family protein 4 1 VEAEAGGS(0.012)GART(0.474)PPLS(0.514)R 51.265 0.035691 13446000.0 10588.0 8920.4 23087.0 32204.0 23244.0 23682.0 9656.7 6094.9 25463.0 20346.0 True False 13954.763755918764 11803.744852070406 22780.85129522217 24779.865346840186 20016.971820645387 22201.16079627893 10516.1275924933 5153.073251868767 26808.922196255233 19633.692732840434 0.7107559411163256 0.6011984099316574 1.1602937667002204 1.262109256981086 1.0195214977141747 1.1307684753130522 0.5356163883986748 0.2624607261602624 1.365454912687571 1.0 14.261043922008353 -7.254678371394704 24.95419023717617 0.7294214000058348 0.9862302219726116 0.06157525957993837 0.3295309796367473 1205.3533873092815 4448846.0640906785 0.13140484111964623 0.09942952474995398 5.563160997883028e-08 7.254678371394704 0.2568088219667768 VEAFEHR ddPTM_PC-9_AZD4547_30min_R2 1 VEAFEHR 7 0 P42285 P42285 SKIV2L2 Superkiller viralicidic activity 2-like 2 0 126.28 0.0038263000000000004 1855500.0 8648.9 7372.9 13716.0 15796.0 15503.0 10416.0 10090.0 14011.0 8422.5 11692.0 False True 11399.07029170436 9756.045740082272 13534.1168781248 12154.476245767215 13350.676051259043 9764.685873407701 10987.990453079972 11845.921890750176 8867.696155125457 11282.66663876783 1.0103170337884981 0.8646932549225544 1.1995494781012912 1.0772698188213592 1.1832908370602233 0.8654590431534804 0.9738823989822286 1.0499221744305527 0.7859574725584456 1.0 13.461820466067818 -6.774571824247216 24.999965933561974 0.9405917547649998 1.0637152324545947 0.26284650810195087 0.11024590702299067 368.16865516707065 700870.728515538 0.03959070137096012 0.03512138082918445 1.6804599858323966e-07 6.774571824247216 0.12312347768959486 VEAPEYIPISDDPKAS(ph)AK ddPTM_PC-9_AZD4547_30min_R2 2 VEAPEYIPISDDPKASAK 18 1 Q1ED39;H3BPL4 Q1ED39 KNOP1 Lysine-rich nucleolar protein 1 1 VEAPEYIPIS(0.001)DDPKAS(0.999)AK;VEAPEYIPISDDPKAS(1)AK 114.87 0.00035424 8912600.0 63047.0 53727.0 48758.0 56212.0 63507.0 69881.0 69254.0 58240.0 75940.0 70665.0 True False 83094.63454093401 71093.20206125134 48111.43706208873 43253.191866742665 54690.149260614635 65511.33002300344 75417.47183722489 49240.34622206054 79954.03336541729 68191.03985875194 1.2185564952969297 1.0425592894390643 0.7055389852060437 0.6342943582666507 0.802013715788724 0.9607029040574957 1.1059733359902044 0.7220940804547772 1.1725005738441694 1.0 16.057294564538203 -8.278256639826761 24.84680463411951 1.0862502775492793 0.8942093944533175 0.1439625266477692 0.18238103533209493 1826.0580320447891 2697896.7014405816 0.1852947021474538 0.048376554125603675 5.269183948612226e-09 8.278256639826761 -0.1920408830959618 VEAPEYIPISDDPKAS(ph)AK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VEAPEYIPISDDPKASAK 18 1 Q1ED39;H3BPL4 Q1ED39 KNOP1 Lysine-rich nucleolar protein 1 1 VEAPEYIPIS(0.036)DDPKAS(0.964)AK;VEAPEYIPISDDPKAS(1)AK 93.255 0.0024456 4694200.0 59072.0 51474.0 41409.0 52752.0 54540.0 36486.0 57195.0 43220.0 36614.0 38503.0 True False 69071.72287481779 56583.99854018516 42396.34760450699 49796.47646429154 43853.27851866592 34572.60993006789 51777.07554405902 42085.5207953753 37149.41048311733 45483.2891104197 1.5186175895752063 1.2440612727636362 0.9321302050425917 1.0948301549476935 0.9641624292430434 0.7601167507067492 1.1383757981609446 0.9252963367096069 0.8167705372610538 1.0 15.473048965611493 -4.697850627183435 1.229754779672411 0.9447532111198254 1.8807061060038393 0.7347607692414028 0.10848432611123297 0.8817029698392742 1.0063790411212448 0.032536213171835256 1.1072222757170733 2.0051615713072106e-05 4.697850627183435 0.9359528948840139 VEAPEYIPISDDPKAS(ph)AK ddPTM_PC-9_Lapatinib_30min_R1 2 VEAPEYIPISDDPKASAK 18 1 Q1ED39;H3BPL4 Q1ED39 KNOP1 Lysine-rich nucleolar protein 1 1 VEAPEYIPIS(0.003)DDPKAS(0.997)AK;VEAPEYIPIS(0.026)DDPKAS(0.974)AK 76.807 0.0024617 16290600.0 114139.0 152752.0 115610.0 142346.0 130067.0 116868.0 108802.0 111208.0 111148.0 101321.0 True False 112511.35692947097 152398.31212905474 106104.99206750547 152814.59969233547 122416.71478156064 111869.82807261412 114435.23518772548 116375.12966476355 98629.34179967205 118834.19984825364 0.9467927336839338 1.282444888118581 0.8928826230411545 1.2859479837241585 1.0301471709144483 0.9413942132438916 0.9629823344950742 0.9793067131631279 0.8299743838526085 1.0 16.858590570263253 -6.569616340485473 5.028584292781764 0.9448381012817498 1.106556114903338 0.2691995264986259 0.12346585491456019 0.2492000746605013 14.185587814530217 0.038257710446512085 0.038764690855743855 2.69391357969324e-07 6.569616340485473 0.16171801362158822 VEAPSLDVHMDS(ph)PDINIEGPDVK ddPTM_PC-9_AZD4547_30min_R2 2 VEAPSLDVHMDSPDINIEGPDVK 23 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VEAPS(0.01)LDVHMDS(0.99)PDINIEGPDVK;VEAPS(0.139)LDVHMDS(0.861)PDINIEGPDVK 68.676 0.00088436 17820400.0 26987.0 29178.0 40386.0 52425.0 47872.0 42818.0 38757.0 67068.0 56911.0 48462.0 True False 35568.30463552883 38609.21789311135 39850.4552522564 40339.2262081759 41225.799130869724 40140.58369120308 42206.29791774238 56704.181669319274 59919.19927389078 46765.360130684756 0.7605694585935829 0.8255943669677461 0.8521361781646755 0.8625877379207353 0.8815456358224367 0.8583400957253641 0.9025119832242886 1.212525286042077 1.2812731283678327 1.0 15.51315267705738 -7.6977546538782615 4.6045493618365025 1.1863791281249971 0.8462076623841336 0.7927224092135825 0.07407004293443992 0.08138242077550696 3.3763053980490616 0.0365471006700359 0.019749375858413697 2.0056047343142268e-08 7.6977546538782615 -0.34017146574086354 VEAPSLDVHMDS(ph)PDINIEGPDVK ddPTM_PC-9_Lapatinib_30min_R1 2 VEAPSLDVHMDSPDINIEGPDVK 23 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VEAPS(0.003)LDVHMDS(0.997)PDINIEGPDVK;VEAPS(0.001)LDVHMDS(0.999)PDINIEGPDVK 62.848 0.0021194000000000005 10520600.0 58065.0 50644.0 54540.8 45958.1 62898.0 58612.0 55253.0 46703.7 60414.7 56154.1 True False 57236.9824521831 50526.73692955811 50056.665957576355 49338.01198572732 59198.463302225864 56105.301391245324 58113.72998499468 48873.72440223926 53610.16029100524 65860.2613643651 0.8690670408294526 0.7671809355572422 0.7600435364300032 0.7491317368567649 0.8988495046309712 0.8518839772112129 0.8823792797220538 0.7420821507502138 0.8139985961247946 1.0 16.00712061678373 -6.25497755426928 24.947750860497347 0.8521962967394722 0.7831067310540629 0.22370220276869002 0.06917136428055863 899.7785779002074 3473853.888487951 0.02058575909381205 0.025951543821368828 5.559329889265349e-07 6.25497755426928 -0.06908956568540925 VEDVEALDR ddPTM_PC-9_AZD4547_30min_R2 2 VEDVEALDR 9 0 P11216;H0Y4Z6 P11216 PYGB Glycogen phosphorylase, brain form;Alpha-1,4 glucan phosphorylase 0 ; 110.87 0.010472 5330900.0 26323.0 25815.0 39117.0 49009.0 43100.0 34817.0 31646.0 40983.0 30797.0 38154.0 False True 34693.16644758684 34159.193910160706 38598.28302140623 37710.73223150201 37116.30896015382 32639.88748602499 34462.4326935747 34650.01904565091 32424.86654667839 36818.24007317379 0.9422820422333195 0.9277791073737255 1.048346769011629 1.0242404894029278 1.0080956853556184 0.8865140599103977 0.9360152094473534 0.9411101393436057 0.8806739942549165 1.0 15.16813304647662 -6.748939566848753 24.995713394355224 0.925629094168336 0.9918110430666578 0.31267442920522526 0.045272373305889464 277.85813999166515 555628.3116688054 0.015554372968012636 0.015451784491440294 1.7826268071189976e-07 6.748939566848753 0.06618194889832174 VEDVEALDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VEDVEALDR 9 0 P11216;H0Y4Z6 P11216 PYGB Glycogen phosphorylase, brain form;Alpha-1,4 glucan phosphorylase 0 101.64 0.015813999999999998 1006500.0 9673.3 13233.0 14370.0 16672.0 16758.0 11294.0 13908.0 13142.0 12793.0 9358.2 False True 11310.798633616178 14546.68478614971 14712.635298528487 15737.921891353273 13474.390198309566 10701.7227580493 12590.533554799764 12797.036425100006 12980.0734230218 11054.767580529566 1.0231602384420593 1.3158743212087385 1.3308859902619223 1.4236320914672154 1.2188759374771125 0.9680640212552208 1.138923406854351 1.1576033898387015 1.1741606803098437 1.0 13.432381073275074 -6.5330094160017165 24.750065306265213 1.099984471865741 1.285620395936866 0.37554773020073595 0.11341738251634077 204.9282832863292 500652.4458842832 0.03802352532994898 0.03806564747729317 2.9308297008172005e-07 6.5330094160017165 0.18563592407112495 VEDVEALDR ddPTM_PC-9_Lapatinib_30min_R1 2 VEDVEALDR 9 0 P11216;H0Y4Z6 P11216 PYGB Glycogen phosphorylase, brain form;Alpha-1,4 glucan phosphorylase 0 ; 107.57 0.011488 5921300.0 38553.0 37166.0 41330.0 34718.0 36195.0 33825.0 35267.0 32324.0 36319.0 34354.0 False True 38003.22715024567 37079.94441047221 37932.006938413644 37271.27753585287 34066.081262107946 32378.383599926165 37092.95269724373 33825.89104456356 32228.371763974967 40292.04312617239 0.943194343142158 0.9202795771452527 0.9414267432314509 0.9250282349579504 0.8454791224022029 0.803592498363386 0.920602427161341 0.8395178903844509 0.7998693852047545 1.0 15.298207342972471 -6.211489805916357 6.252009357957797 0.8595713363181622 0.9328236755468784 0.23377260817073608 0.05579108752547171 0.28861645446239925 27.343573276334194 0.015840455807732728 0.020377672020376787 6.144834551499516e-07 6.211489805916357 0.07325233922871621 VEEAEPEEFVVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VEEAEPEEFVVEK 13 0 Q13185;S4R2Y4;C9JMM0;B8ZZ43 Q13185 CBX3 Chromobox protein homolog 3 0 142.07 4.4723999999999994e-05 0.0 4246.7 4128.2 6389.6 6036.4 3811.6 3887.1 5810.3 4440.3 4232.8 2638.8 False True 4965.5824338517195 4538.020413676657 6541.952296692939 5698.200078272848 3064.7443417995423 3683.253633151532 5259.906321070826 4323.74682988674 4294.696692329136 3117.1935512706928 1.5929657084743902 1.45580322140304 2.09866733941695 1.827990461468148 0.9831742211035404 1.1815928567060234 1.6873852183245657 1.3870639595427776 1.3777446352596379 1.0 11.60603202152756 -9.191789823486335 0.06873543770452926 1.303548400135874e-11 2.502545883604826 0.2967211431842234 0.2833071501618348 78.42260255076013 2.0682772102632123 44.007335262827986 29.875696556989407 6.429988208657027e-10 9.191789823486335 2.502545883591791 VEEAEPEEFVVEK ddPTM_PC-9_Lapatinib_30min_R1 2 VEEAEPEEFVVEK 13 0 Q13185;S4R2Y4;C9JMM0;B8ZZ43 Q13185 CBX3 Chromobox protein homolog 3 0 ; 166.11 4.6568e-18 1674600.0 15502.300000000001 14202.9 18929.2 17163.7 16702.7 16145.0 13427.2 12277.6 13878.5 13189.1 False True 15281.23435922635 14170.014057673567 17372.914244825064 18425.97575442473 15720.280024771657 15454.515985833208 14122.394716205816 12848.062117582398 12315.35718291601 15468.818361628926 0.9878734110119305 0.9160372645413498 1.1230925232090985 1.1911689260073774 1.0162560356753876 0.9990754060548545 0.9129588560711933 0.8305781228547212 0.7961407843190393 1.0 13.91707537537145 -7.2268504890379965 2.0596243638348226 0.861144828020689 1.0507035042841688 0.44616782454146564 0.08545436042486489 0.3093968528921136 2.5665252752134124 0.04518112401869197 0.02974192325897933 5.9312948120717316e-08 7.2268504890379965 0.18955867626347978 VEEAS(ph)PGRPSSVDTLLS(ph)PTALIDSILR ddPTM_PC-9_Lapatinib_30min_R1 1 VEEASPGRPSSVDTLLSPTALIDSILR 27 1 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 2 VEEAS(0.993)PGRPS(0.197)S(0.197)VDT(0.139)LLS(0.374)PT(0.101)ALIDSILR 87.016 2.2513999999999997e-06 10658000.0 29929.0 25038.0 26181.0 15155.0 24869.0 31634.0 27863.0 24073.0 25758.0 23432.0 True False 29502.20697169359 24980.026049330132 24028.499241582584 16269.549255597978 23406.25431433519 30281.087562455697 29305.60980529393 25191.51946280715 22856.86279623524 27482.18997882259 1.073502766498143 0.9089532554930815 0.8743298572675113 0.5920033763006178 0.8516881053646649 1.1018440519401802 1.0663491456785812 0.9166489090650854 0.831697285181728 1.0 14.74620935261736 -6.655939244318418 12.500746071613223 0.9832525682212814 0.84838622453758 0.18035637600405363 0.13015658212862571 0.8931870976604126 99.93503303065144 0.046602382803227434 0.046596345385971065 2.2083136437278836e-07 6.655939244318418 -0.13486634368370143 VEEASPGRPS(ph)SVDTLLSPTALIDSILR ddPTM_PC-9_Lapatinib_30min_R1 1 VEEASPGRPSSVDTLLSPTALIDSILR 27 1 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 1 VEEAS(0.424)PGRPS(0.517)S(0.055)VDT(0.004)LLSPTALIDSILR 78.707 1.5421e-05 66867000.0 28490.0 19422.0 36381.0 26855.0 27333.0 34702.0 34320.0 29846.0 32449.0 21667.0 True False 28083.727375573864 19377.02955228411 33389.8946147212 28830.006285653802 25725.326678745565 33217.87635431303 36096.921670950316 31232.75411817979 28794.251916881632 25412.11208053728 1.1051315721640755 0.7625115728623226 1.3139362249348006 1.1344986278308693 1.0123254059802518 1.3071670803685012 1.4204612964302308 1.229049912073245 1.1330916464410952 1.0 14.63322866684497 -5.269633950005273 24.99498216156093 1.2055390329876172 0.9338215663468523 0.32996588630447043 0.1474415108453899 595.5173745463338 1816443.0210346763 0.03888603168394459 0.08320951890935599 5.374846304787736e-06 5.269633950005273 -0.2717174666407649 VEEASPGRPSSVDTLLSPTALIDSILR ddPTM_PC-9_AZD4547_30min_R2 1 VEEASPGRPSSVDTLLSPTALIDSILR 27 1 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 0 71.426 0.00020841 17289000.0 1259.5 2473.2 5587.7 4574.6 2211.8 5980.7 2427.8 4450.3 4455.6 2786.3 False True 1659.9948007725427 3272.6135339379994 5513.60344706168 3519.9966468654566 1904.729748447058 5606.725883553136 2643.869496728202 3762.608392720398 4691.1139197123175 2688.752485083715 0.617384757422496 1.2171494223039672 2.050617703804749 1.3091560738272496 0.7084065041367145 2.0852517718374397 0.9833071327299525 1.3993881599716118 1.744717650931807 1.0 11.392721237724201 -4.816434828620285 4.156298982778143 1.4167246503718012 0.5798492649169139 0.23378074681538585 0.42878742318260205 0.28927073646581075 9.027454209428463 0.10434390162557547 0.650884949280797 1.526037378835216e-05 4.816434828620285 -0.8368753854548873 VEEEEER ddPTM_PC-9_AZD4547_30min_R2 1 VEEEEER 7 0 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580 P35579 MYH9;MYH10 Myosin-9;Myosin-10 0 129.68 0.020334 19520000.0 34029.0 29181.0 42997.0 66131.0 50969.0 43521.0 35946.0 38737.0 37265.0 47395.0 False True 44849.51415282957 38613.18758444313 42426.83168625928 50885.51966376497 43892.834138980965 40799.62499007075 39145.12436337095 32751.086737705362 39234.75182199471 45735.71547591523 0.9806234293294845 0.8442677059414785 0.9276520820714297 1.112599182810678 0.9597058596819209 0.8920736139255574 0.8558983708035587 0.7160943345240183 0.8578580528089917 1.0 15.481033599886462 -6.993789675756057 2.7204130288481614 0.8347416012756607 0.9639305175607598 0.23137959314948864 0.08965827387709202 0.36730435703777775 5.497501177916051 0.03753394785085417 0.030259302020063234 1.0144025312617901e-07 6.993789675756057 0.1291889162850991 VEEEEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VEEEEER 7 0 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580 P35579 MYH9;MYH10 Myosin-9;Myosin-10 0 ; 129.68 0.020334 46193000.0 104133.0 116038.0 125121.0 120897.0 165462.0 130205.0 115950.0 118468.0 137509.0 116255.0 False True 121760.66017949964 127557.48577157393 128104.35916403471 114123.53304336265 133040.90887890515 123376.82058719757 104966.37659469587 115358.3405272219 139519.80898353062 137331.11122592617 0.8866210947582644 0.9288316728299573 0.932813825071929 0.8310100459000563 0.9687601570487322 0.8983894434832606 0.764330643345728 0.8400015080154968 1.0159373774672498 1.0 17.067298967561484 -8.271534854032556 24.348947480435545 1.0079687311750685 0.8825470319313228 0.45320420426245644 0.05562158088506825 535.8071995878526 1292275.4298449196 0.054855744247993526 0.014868528270163881 5.351372049455473e-09 8.271534854032556 -0.1254216992437457 VEEEEER ddPTM_PC-9_Lapatinib_30min_R1 2 VEEEEER 7 0 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580 P35579 MYH9;MYH10 Myosin-9;Myosin-10 0 ; 143.11 0.0092121 52799000.0 55190.0 53879.0 50519.0 47750.0 49647.0 47324.0 51018.0 51061.0 59919.0 41981.0 False True 54402.98047939353 53754.24648581588 46365.522828979425 51261.69428933044 46726.86106975749 45300.0628376321 53659.4624070088 53433.480467345 53170.29124495766 49237.35991383369 1.104912622744188 1.0917369773661063 0.9416736175562616 1.0411137879658734 0.9490123181163731 0.9200343583999643 1.089811933477219 1.0852222897583177 1.0798769742733298 1.0 15.587465786755004 -9.866180927339734 9.673300014153504 0.9999999999964019 1.0302585271062654 0.01989665987939604 0.06715495833289667 0.0 0.0 0.06994068960583853 0.016963108869024208 1.3608776219277295e-10 9.866180927339734 0.030258527109863542 VEEEIVTLR ddPTM_PC-9_Lapatinib_30min_R1 1 VEEEIVTLR 9 0 A0A087WYR3;O43399;O43399-5;O43399-7;O43399-2;O43399-4;O43399-3;A0A087WZ51;O43399-6 A0A087WYR3 TPD52L2 Tumor protein D54 0 101.25 0.016393 1578600.0 17450.0 25413.0 28347.0 19966.0 21929.0 21801.0 24013.0 25932.0 23848.0 19706.0 False True 17201.159800061912 25354.15775987005 26016.41908258437 21434.366244623503 20639.17933407279 20868.622050613183 25256.275643488618 27136.89538942033 21161.98710942689 23112.155843405504 0.744247309364256 1.0970053132063942 1.1256595559002136 0.9274066162347759 0.8930010455931432 0.9029284066794462 1.092770220770854 1.1741395122672291 0.9156215133200113 1.0 14.496364216573886 -7.270203781439189 24.322055711222855 1.0601444396451802 0.9597189662420221 0.13082877354480626 0.11836213398039432 968.1897986728835 2686805.5397222927 0.050267394717363176 0.034508638068977346 5.3677986721696226e-08 7.270203781439189 -0.1004254734031581 VEEEQEADEEDVS(ph)EEEAESKEGTNKDFPQNAIR ddPTM_PC-9_Lapatinib_30min_R1 1 VEEEQEADEEDVSEEEAESKEGTNKDFPQNAIR 33 2 Q9H3N1 Q9H3N1 TMX1 Thioredoxin-related transmembrane protein 1 1 VEEEQEADEEDVS(0.418)EEEAES(0.418)KEGT(0.163)NKDFPQNAIR 44.015 0.0058323 3557900.0 14891.0 6616.8 7781.3 3231.4 4632.6 2914.7 3190.5 2250.2 6282.0 2616.6 True False 14678.651609325045 6601.479206134977 7141.551550686623 3469.047935634397 4360.119576042029 2790.045075497555 3355.688478763605 2354.7525067589704 5574.455007607336 3068.87582359966 4.783071213389017 2.1511066545506963 2.3270904269791823 1.130396971085442 1.4207546432842613 0.9091423817288741 1.093458540406997 0.7673013318593472 1.8164485394748682 1.0 11.583494555653393 -2.208789127066201 0.7522993879286494 1.1215185533723682 199.99999999896514 0.8887995676994942 0.37809113005738165 33.76750761858188 0.45536931359769217 0.13253431957102377 10983.711462245525 0.006183165526416672 2.208789127066201 198.87848144559277 up VEEIAASK ddPTM_PC-9_Lapatinib_30min_R1 2 VEEIAASK 8 0 M0R117;Q02543;M0R3D6;M0R1A7;M0R0P7 M0R117 RPL18A 60S ribosomal protein L18a 0 ; 109.11 0.017431 22398000.0 125379.0 122155.0 120144.0 120027.0 127593.0 117169.0 119130.0 104028.0 116248.0 106851.0 False True 123591.07246830713 121872.15760268104 110266.22408925176 128854.18597833425 120088.23059748978 112157.95500427943 125297.96849243323 108861.52065288532 103154.92609429132 125320.05297999218 0.9862034808430772 0.9724872812026212 0.8798769348338544 1.0282008578380215 0.9582523127137706 0.8949721320512518 0.9998237753094273 0.8686680069490991 0.823131842361736 1.0 16.935257759168692 -7.774727384792124 24.998193321384683 0.884424921337689 0.9574323037217408 0.18007998292583227 0.059278299567425544 343.1201196124276 645488.5979200781 0.03080936682642203 0.014937390350983305 1.6798581673208097e-08 7.774727384792124 0.0730073823840518 VEELTALGNLGDMPVDFCT(ph)T(ph)RVS(ph)PAHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VEELTALGNLGDMPVDFCTTRVSPAHR 27 1 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 3 VEELTALGNLGDMPVDFCT(1)T(1)RVS(1)PAHR 50.783 0.0075149 4218100.0 5525.2 6492.0 5730.3 6406.8 8759.5 6542.0 7219.2 8032.7 6979.3 5716.3 True False 6460.507232325693 7136.482855866691 5866.932084283764 6047.847767125855 7043.138855596888 6198.926003467194 6535.345113518155 7821.85013634917 7081.359058961619 6752.619939794097 0.9567408339173741 1.0568465157961042 0.8688378935276876 0.8956298179148326 1.043023140409654 0.9180030949078135 0.9678236257610897 1.1583430144282154 1.0486831958704232 1.0 12.721231644721676 -7.64957640383361 8.48389961807717 1.0772230044578663 0.9570708145507055 0.36973222885719337 0.06618957876875022 0.24886067555192948 17.518987397481997 0.031078575008307355 0.017868039834389386 2.240905776776783e-08 7.64957640383361 -0.12015218990716081 VEEPSQCLASGTAIS(ph)ELIIEDNNASPQKLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VEEPSQCLASGTAISELIIEDNNASPQKLR 30 1 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 VEEPSQCLAS(0.001)GT(0.006)AIS(0.906)ELIIEDNNAS(0.087)PQKLR 72.499 1.4546e-05 7980600.0 25557.0 10912.0 18669.0 30240.0 27094.0 35605.0 37208.0 38390.0 38166.0 27855.0 True False 29883.295326241176 11995.271245104335 19114.139762576775 28545.750839402794 21785.125195906396 33737.81112097976 33683.38887740796 37382.30317756725 38724.105547021805 32904.89099994133 0.9081718376242139 0.36454371616443654 0.5808905357750875 0.8675230329574315 0.6620634359781116 1.0253129579137616 1.023659032253534 1.1360713268320477 1.1768495311864382 1.0 15.006014422382737 -6.743064392205173 1.1345420271444677 1.1191354310066186 0.6204811529400124 0.6199592188960178 0.1526507953332333 0.2968754008263792 0.8114108711496784 0.07802887616296637 0.0717033911221619 1.8069061988197492e-07 6.743064392205173 -0.4986542780666062 VEEPSQCLASGTAISELIIEDNNAS(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 2 VEEPSQCLASGTAISELIIEDNNASPQK 28 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 VEEPSQCLASGTAISELIIEDNNAS(1)PQK;VEEPSQCLASGTAISELIIEDNNAS(1)PQK 154.42 5.6185e-12 8824500.0 57754.0 67785.0 73366.0 48565.0 51317.0 69882.0 79994.0 82619.0 70875.0 58480.0 True False 76118.57064217342 89695.17564207809 72393.11890350716 37369.08957177039 44192.520345898214 65512.26749284535 87113.31103108807 69852.13194574908 74621.30780581971 56432.632999926696 1.3488396092075359 1.589420356165104 1.2828236971257605 0.6621893678400391 0.7831022228921273 1.1608933344104366 1.543669086487622 1.2377967894186297 1.3223077471135654 1.0 15.784242043101566 -7.023810606730069 24.642468260534578 1.3038343055308768 1.1238777353716842 0.052280840667142 0.27864384486054894 1979.819353466349 2048981.7464876508 0.11961035851452828 0.09325050527713935 9.466498998179085e-08 7.023810606730069 -0.17995657015919253 VEEPSQCLASGTAISELIIEDNNAS(ph)PQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VEEPSQCLASGTAISELIIEDNNASPQK 28 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 VEEPSQCLASGTAISELIIEDNNAS(1)PQK;VEEPSQCLASGTAISELIIEDNNAS(1)PQK 146.33 3.4665e-13 4849800.0 70262.0 111494.0 79213.0 75723.0 82821.0 60105.0 87481.0 62884.0 62322.0 59259.0 True False 82155.96886224338 122562.38748182364 81101.73833697541 71480.48580727832 66592.8195855231 56952.98799119469 79194.166372407 61233.3616311055 63233.3413483596 70002.18760601412 1.1736200206289709 1.7508365334470475 1.1585600552004418 1.0211178857664327 0.9512962646299055 0.8135886882812455 1.131309878744463 0.8747349722231358 0.9033052181775961 1.0 16.09511238730753 -5.529843870695025 3.6790024972880233 0.9547729823466694 1.467102535801778 0.625741646581187 0.15456104232053267 0.12460198070260559 3.660503576654309 0.03991829331565985 0.08055860020779881 2.952270380096164e-06 5.529843870695025 0.5123295534551086 VEEPSQCLASGTAISELIIEDNNAS(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 2 VEEPSQCLASGTAISELIIEDNNASPQK 28 0 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 VEEPSQCLASGTAISELIIEDNNAS(1)PQK;VEEPSQCLASGTAISELIIEDNNAS(1)PQK 165.53 9.0346e-14 6930900.0 50019.0 79699.0 62839.0 65435.0 64290.0 76114.0 78660.0 77615.0 67774.0 58990.0 True False 49305.719887638785 79514.46186219205 57672.619985554724 70247.30818476104 60508.588599003146 72858.7816504 82732.62991366416 81221.27624748788 60140.5784281407 69186.34290076594 0.7126510496205594 1.1492797353986428 0.8335838775041865 1.0153348947134964 0.874574172619453 1.0530803999121825 1.1957942340199665 1.1739495519221714 0.8692550568021843 1.0 16.078199663453958 -6.873000259325545 6.167470139000774 1.0807869605130414 0.9313016156962289 0.19967210799918478 0.137292842818353 0.3306611008640626 16.70532197569498 0.046548478890789946 0.041085440541844855 1.3396758874795896e-07 6.873000259325545 -0.14948534481681242 VEEPSQCLASGTAISELIIEDNNAS(ph)PQKLR ddPTM_PC-9_AZD4547_30min_R2 2 VEEPSQCLASGTAISELIIEDNNASPQKLR 30 1 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 VEEPSQCLASGTAIS(0.008)ELIIEDNNAS(0.992)PQKLR;VEEPSQCLASGT(0.001)AIS(0.012)ELIIEDNNAS(0.987)PQKLR 79.559 5.7765e-07 23625000.0 53023.0 33922.7 60546.0 75082.0 67740.0 55114.0 53625.0 59004.0 54257.0 63012.0 True False 69883.2110530865 44887.549380445824 59743.120479946374 57773.00490533646 58335.47027751322 51667.7128674148 58397.521114609845 49886.287577034 57124.914252139126 60805.96905936011 1.149282087501393 0.7382095882169992 0.9825206538789611 0.9501206180751299 0.9593707851373088 0.8497144880131036 0.9603912579306303 0.8204176061783329 0.9394622787176131 1.0 15.89192533331116 VEEPSQCLASGTAISELIIEDNNAS(ph)PQKLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VEEPSQCLASGTAISELIIEDNNASPQKLR 30 1 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 VEEPSQCLASGTAIS(0.001)ELIIEDNNAS(0.999)PQKLR;VEEPSQCLASGTAIS(0.001)ELIIEDNNAS(0.999)PQKLR 114.59 3.6273e-17 10473700.0 22860.5 10815.3 18073.2 27627.0 29662.0 32519.0 29947.3 31095.0 32166.0 25107.6 True False 26730.331134543812 11888.971508172368 18504.133630992677 26079.14875794248 23849.94403044864 30813.646393572257 27110.47494432378 30278.789197875845 32636.366897906588 29659.409128347754 0.9012428743563742 0.4008499109582454 0.6238874669052955 0.8792875355367971 0.8041274162691743 1.0389163944645583 0.9140598461353783 1.0208830886295743 1.1003714455900448 1.0 14.85620223640829 -6.215499062843232 1.1885465079886903 1.01475057368103 0.6189190509794238 0.5695290716306414 0.1327305396562941 0.32689049686369026 0.9479844095868526 0.05304143646409475 0.08146022379615084 6.088368595588105e-07 6.215499062843232 -0.39583152270160626 VEEPSQCLASGTAISELIIEDNNAS(ph)PQKLR ddPTM_PC-9_Lapatinib_30min_R1 2 VEEPSQCLASGTAISELIIEDNNASPQKLR 30 1 Q5UIP0;Q5UIP0-2;H7C2B5 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 VEEPSQCLASGTAISELIIEDNNAS(1)PQKLR;VEEPSQCLASGTAISELIIEDNNAS(1)PQKLR 107.51 2.0104e-15 17539000.0 76717.0 47953.0 51714.0 46907.0 36397.0 52143.0 32477.0 26610.0 52710.0 31122.0 True False 75623.00151182535 47841.967774723555 47462.27454181283 50356.697257164895 34256.200019255215 49912.96544126975 34158.500148818566 27846.39774458102 46773.244739093076 36501.39623254168 2.0717838032838323 1.3106887054383838 1.3002865490251938 1.3795827681865758 0.9384901279122898 1.3674261971593131 0.9358135215212843 0.7628858240703525 1.2814097422770323 1.0 15.155664029822587 -1.5228787452816952 0.6154697826606151 1.0471160565381177 67.34164035744045 0.6934929043571032 0.19228931873987098 104.63383621070435 0.7674238696927815 0.08406615477650364 9369.849885369526 0.029999999999906216 1.5228787452816952 66.29452430090234 VEEQEPELTSTPNFVVEVIK ddPTM_PC-9_Lapatinib_30min_R1 2 VEEQEPELTSTPNFVVEVIK 20 0 I3L3Q7;I3L3B0;Q07021 I3L3Q7 C1QBP Complement component 1 Q subcomponent-binding protein, mitochondrial 0 ; 140.35 9.3745e-05 4238100.0 49425.0 45595.0 57238.0 48472.0 48061.0 38180.0 52568.0 45665.0 50054.0 39702.0 False True 48720.19043656507 45489.42757884846 52532.11258506943 52036.79257785183 45234.14647156151 36547.130401926996 55289.713822800586 47786.76260827853 44416.39142801295 46564.43780041034 1.046296116478308 0.9769134929499265 1.128159493951981 1.1175221915251656 0.9714311738380504 0.7848721498277152 1.1873806800758444 1.0262501785827942 0.9538693802853458 1.0 15.506940939675937 -6.279144130320311 24.463760286370483 0.9884956812874767 1.065124780367841 0.1339817346017731 0.09945870123978519 1456.651660092642 2012740.6226974907 0.032272394749345484 0.03667806546578689 5.258427247808364e-07 6.279144130320311 0.0766290990803643 VEESSEIS(ph)PEPK ddPTM_PC-9_AZD4547_30min_R2 1 VEESSEISPEPK 12 0 O94782 O94782 USP1 Ubiquitin carboxyl-terminal hydrolase 1 1 VEES(0.001)S(0.026)EIS(0.973)PEPK 112.5 0.00094624 4430700.0 29280.0 30958.0 25098.0 22797.0 22404.0 34894.0 31173.0 35335.0 30470.0 23775.0 True False 38590.430938165955 40964.56808331418 24765.184121258106 17541.503860138982 19293.591321189942 32712.072663852574 33947.33660989711 29874.787667522487 32080.581994262142 22942.644486546804 1.6820393551752397 1.7855207627584144 1.0794389520257792 0.7645807295852506 0.8409488859274 1.425819620882606 1.4796610142219342 1.3021510090103423 1.3982948658370082 1.0 14.485744072897054 VEESSEIS(ph)PEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VEESSEISPEPK 12 0 O94782 O94782 USP1 Ubiquitin carboxyl-terminal hydrolase 1 1 VEESSEIS(1)PEPK 141.34 7.8148e-05 4058300.0 16152.0 27592.0 17775.0 15600.0 21976.0 16516.0 18174.0 13255.0 13139.0 11433.0 True False 18886.214583458433 30331.151410824663 18198.823412062884 14725.982575882379 17669.960556035974 15649.871885243678 16452.427151634376 12907.070294833395 13331.133018454097 13505.712396421792 1.3983871438327202 2.2458016667718033 1.347490815581449 1.0903521520111656 1.3083323587371414 1.1587594512518984 1.2181828450599383 0.9556748963685172 0.9870736638806297 1.0 13.721282120372122 -5.474427488304043 6.186782519636711 1.1229333278009184 1.8233570280567306 0.6336350829965032 0.21614685766480107 0.12195797820454897 11.317509047703263 0.0541818264342702 0.11184712607678018 3.354073008377599e-06 5.474427488304043 0.7004237002558122 VEESSEIS(ph)PEPK ddPTM_PC-9_Lapatinib_30min_R1 2 VEESSEISPEPK 12 0 O94782 O94782 USP1 Ubiquitin carboxyl-terminal hydrolase 1 1 VEESS(0.004)EIS(0.996)PEPK;VEES(0.001)S(0.056)EIS(0.943)PEPK 184.34 0.00020004 11400900.0 54937.0 71587.0 65648.0 70296.0 74520.0 66749.0 73600.0 75307.0 65945.0 68996.0 True False 54153.58830578806 71421.24469979214 60250.6748486082 75465.80234058155 70136.88011195691 63894.30086951872 77410.64787243429 78806.03814171981 58517.57966836447 80921.86666860875 0.6692083430002652 0.8825951209489078 0.7445536951754558 0.9325761434746571 0.8667234580633375 0.7895801654104035 0.9566097651880225 0.973853438952988 0.7231367994513236 1.0 16.30424197925884 -3.64263887885321 0.6739722715302484 0.8891567224812957 2.30921448260577e-30 0.2980816498740617 0.09206901001513931 16.97380802220749 1.8148504308768585 0.036784390762836176 16.427567730296733 0.0002276989988705677 3.64263887885321 -0.8891567224812957 VEESSWLIEDGK ddPTM_PC-9_Lapatinib_30min_R1 1 VEESSWLIEDGK 12 0 Q9Y266 Q9Y266 NUDC Nuclear migration protein nudC 0 180.97 0.0031928 1854100.0 11141.0 13295.0 13407.0 14112.0 11201.0 8204.3 14505.0 11360.0 12074.0 9532.1 False True 10982.127296990828 13264.216244342362 12304.728212516624 15149.843556251979 10542.179202013293 7853.4212141574035 15255.997926489916 11887.827071718913 10714.098975143414 11179.710784275127 0.9823266011888062 1.186454327870378 1.1006302801521393 1.3551194524245709 0.9429742330044389 0.7024708747567664 1.364614722229515 1.063339410214421 0.9583520702712076 1.0 13.44859524613046 -6.31802069733085 24.999656813654436 1.0112839450611664 1.1543359627546104 0.15159518049867304 0.17445071447916743 612.987271763118 270838.0843460479 0.05576899835897398 0.06323612397457917 4.80816433459201e-07 6.31802069733085 0.143052017693444 VEET(ph)SPLGNAR ddPTM_PC-9_AZD4547_30min_R2 2 VEETSPLGNAR 11 0 P30414;A0A087WYW3 P30414 NKTR NK-tumor recognition protein;Putative peptidyl-prolyl cis-trans isomerase 1 VEET(0.847)S(0.153)PLGNAR;VEET(0.848)S(0.152)PLGNAR 122.18 0.0016989999999999998 20489500.0 82591.0 77892.0 110587.0 96871.0 104516.0 113599.0 106898.0 135418.0 113740.0 89850.0 True False 108853.22000048039 103069.06573892068 109120.5441237379 74538.88759203076 90005.75747748115 106495.63657193206 116411.71491113432 114492.25969606802 119752.06419518784 86704.37884821167 1.2554523940600903 1.188741181334771 1.2585355615633775 0.8596900016148167 1.0380762618119785 1.2282613402763407 1.3426278632931512 1.320489936229207 1.3811535909256767 1.0 16.403817235546434 -6.956300948352489 6.381894060826721 1.2876685405563641 1.1177455697295877 0.16873171984976743 0.14574201136859394 0.299826408903605 30.53338216583396 0.05347232301563721 0.04673582372433557 1.105857204491289e-07 6.956300948352489 -0.16992297082677643 VEET(ph)SPLGNAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VEETSPLGNAR 11 0 P30414;A0A087WYW3 P30414 NKTR NK-tumor recognition protein;Putative peptidyl-prolyl cis-trans isomerase 1 VEET(0.825)S(0.175)PLGNAR;VEET(0.877)S(0.123)PLGNAR 106.67 0.005881399999999999 18499900.0 62648.0 86483.0 78896.0 70366.0 84350.0 68414.0 71131.0 48909.0 61847.0 46701.0 True False 73253.06904559821 95068.46069376441 80777.17985474611 66423.62114964997 67822.22301154159 64826.24940403611 64392.95673615635 47625.19057336903 62751.39537197134 55167.52161508741 1.3278296160682466 1.7232686535580157 1.4642162179831344 1.2040348959864133 1.2293868027051866 1.1750799656424515 1.1672258396060688 0.8632831270844026 1.1374699013995557 1.0 15.751531548819859 -6.165676945550234 0.7504784769611619 1.0221905568579406 1.5718864642778303 0.673311470993232 0.12924355547827604 0.43658602296855575 0.5160683780347503 0.07264162853092053 0.1452199943278288 6.828464476739606e-07 6.165676945550234 0.5496959074198897 VEET(ph)SPLGNAR ddPTM_PC-9_Lapatinib_30min_R1 2 VEETSPLGNAR 11 0 P30414;A0A087WYW3 P30414 NKTR NK-tumor recognition protein;Putative peptidyl-prolyl cis-trans isomerase 1 VEET(0.854)S(0.146)PLGNAR;VEET(0.855)S(0.145)PLGNAR 137.4 0.00014933 18972700.0 73731.0 97567.0 95339.0 76275.0 95163.0 80376.0 87408.0 93271.0 98550.0 82373.0 True False 72679.58241939063 97341.08960599844 87500.59543918254 81884.5179459409 89565.69943765645 76938.50584560721 91933.55854937139 97604.7111625259 87450.2612224932 96611.06329487682 0.7522904721331718 1.0075563427854368 0.9056995384898388 0.8475687478566768 0.927074978610716 0.7963736576501087 0.9515841707359257 1.0102850318976022 0.9051785400143773 1.0 16.559900786485706 -7.499677276008639 24.310661898458722 0.9708260033509305 0.8810645172543378 0.29541431562484655 0.07093589935567675 710.0197578551099 743966.6686574813 0.028661778060474666 0.019162247297540482 3.164628420279745e-08 7.499677276008639 -0.08976148609659274 VEETVKHDWDR ddPTM_PC-9_AZD4547_30min_R2 4 VEETVKHDWDR 11 1 Q16881;Q16881-5;A0A182DWI3;Q16881-2;F8W809;Q16881-3;Q16881-6;Q16881-4;A0A087WSW9;E9PIR7;A0A087WSY9;Q16881-7;E2QRB9;E9PKD3;A0A0B4J225 Q16881 TXNRD1 Thioredoxin reductase 1, cytoplasmic 0 ;;; 88.134 0.0045027999999999995 140570800.0 106853.0 80864.0 130849.0 214393.0 184509.0 141532.0 114795.0 129508.0 108491.0 143135.0 False True 140830.03131953056 107001.70661829312 129113.85676478218 164968.006188831 158893.11020716978 132681.98166620024 125011.53261261812 109495.51439777837 114225.61277123372 138123.88721690333 1.019592151344377 0.7746792301773452 0.9347684847735843 1.194348128428886 1.1503666267200505 0.9606012713633133 0.9050681611378764 0.7927340925891531 0.8269794245788864 1.0 17.07560331604045 -7.271419156528891 3.1463460662882308 0.8584958913628856 1.0094682451235062 0.21000909566330417 0.11918512643516241 0.42223909409031174 8.614293924008885 0.058908909783028596 0.04011149474038366 5.3527978627940385e-08 7.271419156528891 0.15097235376062057 VEETVKHDWDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VEETVKHDWDR 11 1 Q16881;Q16881-5;A0A182DWI3;Q16881-2;F8W809;Q16881-3;Q16881-6;Q16881-4;A0A087WSW9;E9PIR7;A0A087WSY9;Q16881-7;E2QRB9;E9PKD3;A0A0B4J225 Q16881 TXNRD1 Thioredoxin reductase 1, cytoplasmic 0 ;;; 87.789 0.0045875 75615500.0 139167.0 77098.0 128410.0 189218.0 186990.0 202289.0 186759.0 199976.0 199928.0 155874.0 False True 162725.22442645908 84751.7799170686 131471.7813976366 178616.72891303292 150350.65181894644 191680.60873056797 169067.83550193082 194726.84189208585 202851.56877338432 184132.72230209474 0.8837387640393772 0.460275495074807 0.7140055268500255 0.9700433832721373 0.8165341278791054 1.0409915539948944 0.918184630022208 1.0575352357665686 1.1016595325223009 1.0 17.490386505839496 -6.017474896099809 1.0741171567124843 1.020478060040076 0.6486523396274961 0.5460587874999496 0.12343539669120636 0.3875316038108791 0.9114429931956822 0.04926225336870181 0.09922884320162986 9.605613409413853e-07 6.017474896099809 -0.3718257204125799 VEETVKHDWDR ddPTM_PC-9_Lapatinib_30min_R1 4 VEETVKHDWDR 11 1 Q16881;Q16881-5;A0A182DWI3;Q16881-2;F8W809;Q16881-3;Q16881-6;Q16881-4;A0A087WSW9;E9PIR7;A0A087WSY9;Q16881-7;E2QRB9;E9PKD3;A0A0B4J225 Q16881 TXNRD1 Thioredoxin reductase 1, cytoplasmic 0 ;;; 97.59700000000001 0.0023991 89683900.0 250028.0 142497.0 163333.0 148830.0 140553.0 143311.0 100962.0 103988.0 166703.0 117683.0 False True 246462.55487048044 142167.0569514895 149904.39122361314 159775.45468232568 132285.94887782997 137181.92260425782 106189.31834913998 108819.66210685797 147927.1526795871 138024.3497472593 1.785645469960813 1.0300143214716537 1.086072069878306 1.1575888962700822 0.9584247208558702 0.9938965324267489 0.769352063919059 0.7884091633550244 1.0717467820023145 1.0 17.074563278836983 -2.444247562743357 1.1477562618164054 0.9518009062049582 199.9999999773652 0.7983232399753766 0.12001207050622521 171.02016079232632 1.2373622947331786 0.03876447864647176 88482.30141770534 0.0035954432413882573 2.444247562743357 199.04819907116024 VEFMDDTSR ddPTM_PC-9_Lapatinib_30min_R1 2 VEFMDDTSR 9 0 P62857 P62857 RPS28 40S ribosomal protein S28 0 ; 138.06 0.0041905 18627800.0 58057.0 51042.0 68086.0 54704.0 63445.0 61683.0 51671.0 50363.0 62767.0 48819.0 False True 57229.09653365014 50923.81538501115 62488.23189956038 58727.11464719444 59713.28983766922 59044.961880095994 54346.271551855265 52703.04883917073 55697.519494188076 57257.29910277147 0.9995074415041704 0.8893855662595557 1.0913583574279304 1.0256703611147426 1.0428939327104738 1.0312215700938991 0.9491588391954853 0.9204599180372395 0.9727584145074022 1.0 15.805171997792074 -7.269849391789467 23.532574722748606 0.9539659436612464 1.0131554504513836 0.19636103993598397 0.05158137932657206 458.0180966968567 1281598.9525371327 0.022186241978554736 0.015262743896828655 5.3721806496725466e-08 7.269849391789467 0.059189506790137125 VEGDLKGPEVDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VEGDLKGPEVDLK 13 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 70.54 0.036256000000000004 3870800.0 39334.0 33153.0 32261.0 42731.0 46968.0 33965.0 39706.0 28419.0 32042.0 30474.0 False True 45992.4693180878 36444.210739456015 33030.22459052383 40336.920605771156 37764.9575626091 32183.815608034718 35944.76023345409 27673.031362419486 32510.55363249156 35998.69496794873 1.277614906846956 1.012375886734337 0.9175395002494434 1.120510636335149 1.0490646284881426 0.8940272872860927 0.9985017586181205 0.7687231825225342 0.9031036725480515 1.0 15.135656986176752 -6.728489167918566 5.50304435131249 0.9033446675109257 1.0670968548114503 0.3743935581346616 0.10454970889914887 0.21042186203837918 16.570903640775406 0.03587463637408986 0.03485195445464029 1.868576282310449e-07 6.728489167918566 0.16375218730052465 VEGDNIY(ph)VR ddPTM_PC-9_AZD4547_30min_R2 2 VEGDNIYVR 9 0 O43491;E9PMV8;E9PPC9;Q6ZSX4 O43491 EPB41L2 Band 4.1-like protein 2 1 VEGDNIY(1)VR;VEGDNIY(1)VR 149.72 0.00036960000000000004 56172000.0 41388.0 60308.0 75213.0 102982.0 96684.0 98981.0 50853.0 75217.0 70821.0 74599.0 True False 54548.52307612066 79801.38161278209 74215.62647669886 79241.09095603944 83261.09548732045 92791.7024227886 55378.818484685406 63593.9409647103 74564.45347606286 71987.31171616842 0.7577519117701546 1.1085478775401836 1.0309542710709387 1.1007646912621383 1.1566079285694444 1.2890008004278273 0.7692858250219569 0.883404859115291 1.0357999444409813 1.0 16.135455023086493 -10.290039634807675 3.1888125394834863 0.9999992938367297 1.0216152725741667 0.0 0.16007014417043927 20191891.082711272 36118557.8351238 634.9470575310007 0.043533457981081394 5.128145811061346e-11 10.290039634807675 0.021615978737437036 VEGDNIY(ph)VR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VEGDNIYVR 9 0 O43491;E9PMV8;E9PPC9;Q6ZSX4 O43491 EPB41L2 Band 4.1-like protein 2 1 VEGDNIY(1)VR;VEGDNIY(1)VR;VEGDNIY(1)VR 109.44 0.0034344 41998700.0 83395.0 114450.0 145616.0 93108.0 156911.0 106776.0 121761.0 93018.0 105481.0 86964.0 True False 97512.12637366998 125811.83962630067 149088.03769175502 87891.46062020896 126165.41594503853 101176.4785915949 110226.91660669917 90576.37606071777 107023.46007455341 102729.88479335475 0.9492089528750032 1.224685882587878 1.4512625804229367 0.8555588356494912 1.2281276884406644 0.9848787311999367 1.072978100076964 0.8816945160886314 1.0417948028447162 1.0 16.648496406544695 -6.713579739134073 1.015366033890239 0.9789131142243648 1.168699900206253 0.1464082564225867 0.1608934878746051 0.9301638260069283 2.062336638956775 0.088569770961726 0.08458563017590948 1.9338387613481075e-07 6.713579739134073 0.18978678598188825 VEGDNIY(ph)VR ddPTM_PC-9_Lapatinib_30min_R1 2 VEGDNIYVR 9 0 O43491;E9PMV8;E9PPC9;Q6ZSX4 O43491 EPB41L2 Band 4.1-like protein 2 1 VEGDNIY(1)VR;VEGDNIY(1)VR 140.11 0.00115 48347000.0 83028.0 93610.0 106086.0 69204.0 105863.0 91065.0 92781.0 71991.0 116690.0 69649.0 True False 81844.00549452967 93393.25179638143 97364.01858380243 74293.49301777662 99636.34647466594 87170.36223288323 97584.74619908037 75335.96467606667 103547.14339982497 81687.73684854123 1.001913000066071 1.143295865443593 1.1919049583210621 0.9094815927576202 1.2197222045630125 1.0671168720772304 1.194607048301682 0.9222432593003341 1.2675971620050348 1.0 16.317831893468636 -4.745295627550343 23.92152510268944 1.1016557078199476 1.0019125109598375 0.05998618331229688 0.1185924042710381 1645.717060983601 2438358.8752538078 0.027033657269373165 0.6471563673136572 1.7976468267129386e-05 4.745295627550343 -0.09974319686011013 VEGFLEEDRR ddPTM_PC-9_AZD4547_30min_R2 2 VEGFLEEDRR 10 1 Q9NX02;A0A0G2JPQ2;J3KN39;A0A0G2JLX3;A0A0G2JMG8;A0A0G2JPB6;A0A0G2JP37;A0A0G2JLQ8;A0A0G2JNC8;Q9NX02-4;Q9NX02-5;Q9NX02-2;Q9NX02-3;Q8WX94;Q8WX94-2;Q8WX94-3;K7ERG0;A0A0G2JM25;A0A0G2JNK1;A0A0G2JPH3;A0A0G2JMB6;A0A0G2JNK3 Q9NX02 NLRP2;NLRP7 NACHT, LRR and PYD domains-containing protein 2;NACHT, LRR and PYD domains-containing protein 7 0 ; 117.31 0.00061217 8000100.0 21560.1 23244.0 28459.0 36806.0 32752.0 26740.0 22453.5 33365.0 23555.4 25555.3 False True 28415.763322061182 30757.168438805962 28081.615065219725 28320.945347031422 28204.95014067189 25067.94357286118 24451.81800180686 28209.20590142599 24800.490354697806 24660.616725427924 1.152273020518634 1.2472181365639488 1.1387231462165486 1.1484281055237877 1.14372444350061 1.0165173017353315 0.9915331102240533 1.143897016668649 1.0056719436836166 1.0 14.58992125940337 -6.656345557891696 4.284819624641166 1.038138770197115 1.1716871946286682 0.65222338489852 0.049236624188815505 0.1480399866855767 4.847477873950782 0.017048181069155954 0.01688506694257844 2.2062485744106124e-07 6.656345557891696 0.13354842443155324 VEGFLEEDRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VEGFLEEDRR 10 1 Q9NX02;A0A0G2JPQ2;J3KN39;A0A0G2JLX3;A0A0G2JMG8;A0A0G2JPB6;A0A0G2JP37;A0A0G2JLQ8;A0A0G2JNC8;Q9NX02-4;Q9NX02-5;Q9NX02-2;Q9NX02-3;Q8WX94;Q8WX94-2;Q8WX94-3;K7ERG0;A0A0G2JM25;A0A0G2JNK1;A0A0G2JPH3;A0A0G2JMB6;A0A0G2JNK3 Q9NX02 NLRP2;NLRP7 NACHT, LRR and PYD domains-containing protein 2;NACHT, LRR and PYD domains-containing protein 7 0 ; 135.43 7.1758e-05 5100200.0 17820.8 15941.5 17633.4 19061.3 20509.8 18076.2 19228.2 20378.8 16626.1 11768.6 False True 20837.509463156035 17524.066766296794 18053.847131041905 17993.357158568393 16491.051920831203 17128.25225066855 17406.765695887327 19843.87809312342 16869.225259009032 13902.154019813655 1.4988691272919261 1.2605288893592395 1.2986366792736697 1.2942855569664862 1.186222789456065 1.2320574370170974 1.252091270969867 1.42739593194274 1.213425288985192 1.0 13.763020813069684 -13.325204807735389 0.2866478388971988 2.929541079199129e-26 1.3115165255429038 0.5026165431152947 0.09015141870176635 100.52351279874458 1.8029592103066974 59.55004993512616 0.10143790896200636 4.7292817947075874e-14 13.325204807735389 1.3115165255429038 VEGIYTYSLS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VEGIYTYSLSPSK 13 0 O95197-7;O95197-2;O95197 O95197-7 RTN3 Reticulon-3 1 VEGIYTYS(0.042)LS(0.925)PS(0.032)K;VEGIYTYS(0.019)LS(0.962)PS(0.019)K 115.91 0.0009822000000000001 0.0 17754.4 21971.0 17497.9 22312.0 22429.0 18594.1 23124.0 19926.9 16278.400000000001 14155.7 True False 20759.869254615816 24152.135678719515 17915.116297155295 21061.930976479987 18034.198457923696 17618.9926629577 20933.527316737833 19403.839989295793 16516.440804292823 16722.016353540457 1.2414692591913683 1.4443315428049992 1.0713490477697225 1.259532973248209 1.0784703277787082 1.0536404396726553 1.2518542545442313 1.1603768097731544 0.987706294211098 1.0 14.02946119873037 -1.5228787452803876 0.18583895987026633 1.0079326516313523 2.439257601306996 0.40711387591472503 0.10520075816936104 57.02618119666972 0.65672739791846 0.22348719990604465 23.255797523502018 0.029999999999996543 1.5228787452803876 1.431324949675644 VEGNAVACPVSSAQS(ph)PPHSAGAPAAK ddPTM_PC-9_Lapatinib_30min_R1 1 VEGNAVACPVSSAQSPPHSAGAPAAK 26 0 Q8NEZ4;Q8NEZ4-3;H0Y765;H7BY37;Q8NEZ4-2 Q8NEZ4 KMT2C Histone-lysine N-methyltransferase 2C 1 VEGNAVACPVS(0.013)S(0.067)AQS(0.919)PPHSAGAPAAK 112.57 7.904000000000002e-11 11522000.0 26613.0 41195.0 46930.0 44054.0 42464.0 45417.0 44472.0 51666.0 51757.0 36221.0 True False 26233.493739773523 41099.61550851324 43071.59655503876 47293.878119835885 39966.35100743613 43474.620782198006 46774.54255683281 54066.59097600608 45927.58163462796 42481.751588551284 0.617523825143862 0.9674651814401521 1.0138846668141255 1.1132751440640092 0.9407886801495953 1.0233716632793997 1.1010502346950877 1.2727015472350929 1.0811131819481126 1.0 15.374555631473523 -4.421282518645686 1.3397997865760423 1.0804388907730151 4.3872803570118284e-14 0.7217318422970012 0.08404808756156026 1.723201355684156 1.4571898279728734 0.02636507625678529 3.201136802884335 3.790683120094298e-05 4.421282518645686 -1.0804388907729712 VEGNFNPFAS(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 1 VEGNFNPFASPQK 13 0 Q5TH58;Q9H6K1-2;Q9H6K1 Q5TH58 C6orf106 Uncharacterized protein C6orf106 1 VEGNFNPFAS(1)PQK 155.37 5.3825e-12 0.0 38275.0 39549.0 49589.0 55407.0 55268.0 50853.0 50134.0 59779.0 49597.0 51846.0 True False 50445.65383054307 52332.440827152655 48931.417459123026 42633.77217961666 47594.99219512256 47673.15387100634 54595.828877572974 50541.52913476235 52218.59616571773 50030.887320694244 1.0082902089501273 1.0460026521557697 0.9780241782536516 0.8521490315839767 0.9513121742183428 0.952874442650297 1.0912424664311426 1.0102065312332946 1.043727164601348 1.0 15.610531418964081 -7.237519897685067 24.67424937090572 1.037144590753327 0.9633384528363259 0.31418877614757823 0.05173220273951265 879.7208791668735 907481.7070605813 0.021758885680120858 0.016845548763434432 5.7873547233188505e-08 7.237519897685067 -0.07380613791700108 VEGNFNPFAS(ph)PQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VEGNFNPFASPQK 13 0 Q5TH58;Q9H6K1-2;Q9H6K1 Q5TH58 C6orf106 Uncharacterized protein C6orf106 1 VEGNFNPFAS(1)PQK;VEGNFNPFAS(1)PQK;VEGNFNPFAS(1)PQK;VEGNFNPFAS(1)PQK 151.49 0.00013396 25942300.0 120667.0 120534.0 131849.0 152004.0 152915.0 147150.0 156649.0 155566.0 143640.0 118552.0 True False 141093.53981811384 132499.81893854527 134992.78020011674 143487.70868361715 122952.40345951222 139433.19495722975 141810.07267945237 151482.55733580166 145740.46325981757 140044.53914288426 1.0074904789694035 0.9461262806067627 0.963927483544265 1.024586246359952 0.8779521444536061 0.9956346445966682 1.0126069431009144 1.0816741464031485 1.0406722329324236 1.0 17.09552620290399 -7.301956681049647 2.8362005674498567 1.044810301560597 0.9650995921191649 0.37396778453915824 0.04188205036758356 0.26450443927810807 4.234551035817038 0.01884304701612946 0.012368060539314165 4.989342514590708e-08 7.301956681049647 -0.0797107094414321 VEGNFNPFAS(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 2 VEGNFNPFASPQK 13 0 Q5TH58;Q9H6K1-2;Q9H6K1 Q5TH58 C6orf106 Uncharacterized protein C6orf106 1 VEGNFNPFAS(1)PQK;VEGNFNPFAS(1)PQK 163.23 0.00034375 32954000.0 104526.0 100183.0 106665.0 101204.0 107220.0 94019.0 82855.0 79407.0 91657.0 92881.0 True False 103035.4400722793 99951.03241872507 97895.41543880713 108646.87976664711 100913.53040263051 89998.02653899355 87144.82648737145 83096.5391095054 81333.62346900112 108935.35709384715 0.9458402012077208 0.9175260914839417 0.8986560291391051 0.9973518485191954 0.9263615881452898 0.8261599258490592 0.7999682455008313 0.7628059550758917 0.7466228196134034 1.0 16.73311275929965 -6.7767423064600125 4.125852027759197 0.8085210889997859 0.9384878110213372 0.37520181432025024 0.06944850956474662 0.19505880865897582 7.494162428133702 0.02369466705184455 0.021883613191132405 1.6720824690512862e-07 6.7767423064600125 0.12996672202155124 VEHHDHAVVSGR ddPTM_PC-9_AZD4547_30min_R2 4 VEHHDHAVVSGR 12 0 O95831-3;O95831;E9PMA0;O95831-5;O95831-2 O95831-3 AIFM1 Apoptosis-inducing factor 1, mitochondrial 0 ;;; 93.62299999999999 0.0021944000000000004 5075180.0 9070.8 7105.3 15237.099999999999 19121.2 17763.5 14758.5 14191.800000000001 18246.0 13032.2 16212.7 False True 11955.125715639197 9401.949273285483 15035.046098255723 14713.102759595107 15297.344645329295 13835.648661932371 15454.842706840474 15426.499951368769 13721.055486236392 15645.098307761822 0.7641451322621627 0.6009517542386424 0.9610068152014462 0.9404289107148445 0.977772356837157 0.8843439900322168 0.9878392837693478 0.9860276776730382 0.8770194482849061 1.0 13.933423103495805 -5.270906280108627 24.993960913558656 0.9507045687805395 0.6825484424477808 0.7991553518940673 0.053991121590271515 221.2035378570234 584009.4246921749 0.013120542778938479 0.02789845927747749 5.359122938503211e-06 5.270906280108627 -0.26815612633275876 VEHHDHAVVSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VEHHDHAVVSGR 12 0 O95831-3;O95831;E9PMA0;O95831-5;O95831-2 O95831-3 AIFM1 Apoptosis-inducing factor 1, mitochondrial 0 ;;; 103.44 0.00088116 3849240.0 10003.6 13757.5 15200.7 12675.899999999998 17324.1 12649.9 11578.8 11092.400000000001 10700.1 12060.399999999998 False True 11697.011899893814 15123.25367984996 15563.142336975767 11965.710418822275 13929.56696709242 11986.516975123755 10481.972240747447 10801.23625336929 10856.568719899587 14246.855049926122 0.8210241389347518 1.0615152345449308 1.0923914283143121 0.8398843377636753 0.9777292545111318 0.8413447692924981 0.7357393757439683 0.758148813581514 0.7620326508449937 1.0 13.798355863414507 -6.866891098569027 3.8243180770179164 0.7929361822913423 0.965576379897485 0.2959060755668974 0.10525948332202982 0.2501630271100331 6.899697333360734 0.038069488000876034 0.03358483377373084 1.358654092927069e-07 6.866891098569027 0.1726401976061427 VEHHDHAVVSGR ddPTM_PC-9_Lapatinib_30min_R1 4 VEHHDHAVVSGR 12 0 O95831-3;O95831;E9PMA0;O95831-5;O95831-2 O95831-3 AIFM1 Apoptosis-inducing factor 1, mitochondrial 0 ;;; 82.85 0.004906000000000001 2595050.0 15468.0 18015.5 16070.300000000001 7368.61 13611.4 8828.99 8838.1 11281.85 17362.0 7959.7 False True 15247.423483516211 17973.786216619024 14749.061967151922 7910.522160362372 12810.804213042022 8451.394679080922 9295.693572844573 11806.045937418308 15406.50873003478 9335.52353936643 1.6332692450744977 1.9253110059469514 1.57988589552128 0.847357100756583 1.372264143411013 0.9052941319726445 0.9957335047837542 1.2646367274030295 1.6503100940261104 1.0 13.188515216215686 -5.578000284610207 6.327718055160621 1.1533162537862822 1.7740058597662287 0.5564578268666036 0.2354473329917116 0.13648771108144656 11.466950810982793 0.06446232841247906 0.11351092607557892 2.6424070256484214e-06 5.578000284610207 0.6206896059799465 VEHS(ph)PGPPLADAECQEGLSENSACR ddPTM_PC-9_AZD4547_30min_R2 2 VEHSPGPPLADAECQEGLSENSACR 25 0 A0A087WUE6;Q3T8J9-2;Q3T8J9-3;Q3T8J9 A0A087WUE6 GON4L GON-4-like protein 1 VEHS(1)PGPPLADAECQEGLSENSACR;VEHS(1)PGPPLADAECQEGLSENSACR 136.18 4.1836999999999995e-07 14088700.0 23529.4 26397.5 36997.0 48259.0 44782.0 42085.0 31196.0 39144.0 26970.0 38838.0 True False 31011.259758076576 34929.97564375236 36506.39560658962 37133.63314411753 38564.79229358722 39453.41829707791 33972.383565340206 33095.194239634955 28395.579139653735 37478.29344136715 0.8274458869529929 0.9320055006879783 0.9740677137207966 0.990803735559923 1.028990083391066 1.0527005013929127 0.9064549221935156 0.883049658902177 0.7576540053531827 1.0 15.193767641518539 -10.611756680869387 4.533919777847898 1.0000038801768583 0.936105533538714 0.05219720260136562 0.08603354469683235 4.433884268759692e-06 8.909914576680951e-07 0.08986525301091182 0.021793913164837277 2.4447998999945156e-11 10.611756680869387 -0.06389834663814431 VEHS(ph)PGPPLADAECQEGLSENSACR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VEHSPGPPLADAECQEGLSENSACR 25 0 A0A087WUE6;Q3T8J9-2;Q3T8J9-3;Q3T8J9 A0A087WUE6 GON4L GON-4-like protein 1 VEHS(1)PGPPLADAECQEGLSENSACR;VEHS(1)PGPPLADAECQEGLSENSACR 129.42 1.0404000000000001e-07 9833600.0 33501.0 32503.0 43330.0 43453.0 45547.0 40449.0 41494.0 44133.0 38123.0 32463.0 True False 39172.05762508922 35729.683035156326 44363.15152994008 41018.46928652678 36622.39231187525 38327.7832336051 37563.38792945511 42974.55551277875 38680.47675336978 38348.284923033396 1.0214813440473067 0.9317152802756965 1.1568483862832137 1.0696298248761986 0.9549942685931826 0.9994653818425141 0.9795324094635885 1.1206382658059018 1.0086624951025347 1.0 15.22687443606868 -10.741320527171018 2.2006042801595362 0.9994858971448227 1.0276978766315574 0.0142424364257131 0.06715094900647013 1117235.2323374632 1075396.2655100913 4007.7209451576578 0.01809011120483404 1.814176231960226e-11 10.741320527171018 0.028211979486734706 VEHS(ph)PGPPLADAECQEGLSENSACR ddPTM_PC-9_Lapatinib_30min_R1 2 VEHSPGPPLADAECQEGLSENSACR 25 0 A0A087WUE6;Q3T8J9-2;Q3T8J9-3;Q3T8J9 A0A087WUE6 GON4L GON-4-like protein 1 VEHS(1)PGPPLADAECQEGLSENSACR;VEHS(1)PGPPLADAECQEGLSENSACR 155.95 4.8531e-09 8800200.0 33206.3 42196.8 50359.5 40046.3 48282.4 46005.0 40756.0 45328.7 44268.3 34363.7 True False 32732.772072710395 42099.09590216367 46219.136303291634 42991.438492540605 45442.52415885067 44037.47339289291 42866.14625936046 47434.83688255499 39282.33788813496 40303.419758247954 0.8121586770812853 1.0445539399556347 1.1467795184758 1.0666945571967887 1.127510380792216 1.092648555806007 1.0635858325790841 1.1769432263337312 0.9746651307447917 1.0 15.298614636638865 -4.774654512645817 3.7695254368786175 1.0888460513765763 0.7816530032706287 0.6470600218774909 0.05897387039525547 0.14162643127235122 3.550309197820701 0.013541959452320005 0.12291043503787857 1.6801400616254323e-05 4.774654512645817 -0.3071930481059476 VEHS(ph)PGPPPVDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VEHSPGPPPVDK 12 0 Q9H869-7;Q9H869-5;Q9H869-6;Q9H869-4;Q9H869-3;Q9H869-2;Q9H869;Q9H869-8;Q9H869-9 Q9H869-7 YY1AP1 YY1-associated protein 1 1 VEHS(1)PGPPPVDK;VEHS(1)PGPPPVDK 77.068 0.010183 7758400.0 96383.0 119470.0 96723.0 101609.0 121995.0 108373.0 122729.0 96813.0 99945.0 87760.0 True False 112698.73824897672 131330.19205027612 99029.24314401994 95916.17715082271 98090.95549843503 102689.72910023702 111103.22063898639 94271.7613318524 101406.50654763667 103670.19329222223 1.0870891108624166 1.2668076317759607 0.9552335150459252 0.925204961087101 0.9461828167131836 0.9905424677928253 1.0716987893117182 0.9093429686787808 0.9781645362789596 1.0 16.661641632129353 -5.27462364483051 24.945104713156315 0.9704314978966949 1.1769483704956076 0.6616630757774973 0.05859967535668417 367.7053888385658 695711.9818105947 0.015038612809878841 0.031609163437860785 5.313447026757317e-06 5.27462364483051 0.20651687259891272 VEILANDQGNR ddPTM_PC-9_AZD4547_30min_R2 2 VEILANDQGNR 11 0 P17066;P48741 P17066 HSPA6;HSPA7 Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7 0 ; 147.3 3.8781e-07 48973000.0 128203.0 129381.0 184466.0 249970.0 198320.0 178429.0 162770.0 206582.0 161987.0 167765.0 False True 168968.8872119431 171200.87806664727 182019.860312057 192343.27849800178 170786.69125238282 167271.80642341217 177256.21467272803 174659.49868210327 170549.30211698523 161891.59841369215 1.043716220406731 1.0575031672067783 1.1243317262637051 1.188099199604506 1.05494474652082 1.0332333985360478 1.0949068167192573 1.0788669726750395 1.05347840028838 1.0 17.304668591384193 VEILANDQGNR ddPTM_PC-9_Lapatinib_30min_R1 1 VEILANDQGNR 11 0 P17066;P48741 P17066 HSPA6;HSPA7 Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7 0 121.61 0.0034606000000000003 83373000.0 89355.0 101320.0 94167.0 104110.0 77137.0 98815.0 86467.0 80363.0 105960.0 73240.0 False True 88080.78131430005 101085.39976508234 86424.952755132 111766.59670077909 72599.95331717687 94588.91279901574 90943.8381737196 84096.95835955505 94025.66899173406 85899.43641383442 1.0253941701078997 1.1767876948352383 1.0061178089547156 1.3011330617156256 0.8451738026244416 1.1011587124194664 1.0587245035646446 0.9790164158284387 1.094601698418022 1.0 16.390361045422694 -6.26323110660153 24.999047455625764 1.0187462602480017 1.1222288278094177 0.22972257857635692 0.10200173351807487 260.161693059258 3629900.5987300826 0.02930770561935268 0.03496560415720165 5.45467517334594e-07 6.26323110660153 0.10348256756141594 VELCSFSGYK ddPTM_PC-9_Lapatinib_30min_R1 2 VELCSFSGYK 10 0 C9JXB8;C9JNW5;P83731 C9JXB8 RPL24 60S ribosomal protein L24 0 ; 153.24 0.00054486 8628000.0 56111.0 51322.0 52957.0 58692.0 60447.0 59576.0 63225.0 48751.0 50046.0 51432.0 False True 55310.84685050285 51203.16706221427 48603.07987993159 63008.405470772435 56891.626303374476 57028.0733584391 66498.48113769913 51016.14943427538 44409.29247225669 60321.95267116781 0.9169273274692892 0.8488313921357512 0.8057278938710896 1.044535242654515 0.94313303505785 0.945395015133469 1.102392714310847 0.8457310676326905 0.7362044911633485 1.0 15.880395510135697 -3.3980000424732566 23.859312824431246 0.919510580530082 0.9192200898305153 0.0 0.10666624186165424 0.0 0.0 0.025212474138746895 0.0 0.00039994471064718775 3.3980000424732566 -0.00029049069956665896 VELQELNDR ddPTM_PC-9_Lapatinib_30min_R1 4 VELQELNDR 9 0 P08670;B0YJC4;A0A1B0GTT5;P17661 P08670 VIM;DES Vimentin;Desmin 0 ;;; 162.64 0.00077678 51713800.0 118979.0 128107.0 138498.0 115426.0 140677.0 122924.0 125322.0 106417.0 109127.0 125994.0 False True 117282.33764192338 127810.37611237045 127111.22905774017 123914.81308984829 132402.65544162336 117666.82706983948 131810.5599547447 111361.52231435856 96835.96810174563 147771.895023548 0.7936714733423025 0.8649166750687158 0.8601854164317547 0.8385546728632127 0.8959934865863669 0.7962733850783252 0.8919866658929982 0.7536042107101131 0.6553070736916141 1.0 17.173012381500385 -7.770455389278344 24.988145005497287 0.7783417262673695 0.8492564999467974 0.033253539535165744 0.08675724820635847 413.90491768019035 1147130.4613926741 0.04335520192836381 0.021299665605394345 1.6964638540480524e-08 7.770455389278344 0.07091477367942789 VELS(ph)PGPPKPAGR ddPTM_PC-9_AZD4547_30min_R2 3 VELSPGPPKPAGR 13 1 A0A087WXE2;Q8IZ73-2;Q8IZ73 A0A087WXE2 RPUSD2 RNA pseudouridylate synthase domain-containing protein 2 1 VELS(1)PGPPKPAGR;VELS(1)PGPPKPAGR;VELS(1)PGPPKPAGR 139.19 0.00032507 109992000.0 158316.0 147018.0 192147.0 231533.0 191177.0 199431.0 175490.0 206071.0 175601.0 194809.0 True False 208657.19482263294 194538.6934063143 189599.00523338042 178156.64399919106 164635.37350522826 186960.54804335375 191108.27003082263 174227.4619904914 184882.91036345315 187988.79620524473 1.1099448426427638 1.0348419551233172 1.0085654520941645 0.9476982011453544 0.8757722631804111 0.9945302689168329 1.0165939347905186 0.926797051246986 0.9834783460265334 1.0 17.52028715686746 -5.013058495351912 1.5006909303021922 0.9617248709057395 1.1285462694223491 0.5650417502745231 0.03981422734279182 0.5568381295675506 1.6118182924023379 0.012161786801068643 0.12202533858188017 9.703792575510466e-06 5.013058495351912 0.1668213985166096 VELS(ph)PGPPKPAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VELSPGPPKPAGR 13 1 A0A087WXE2;Q8IZ73-2;Q8IZ73 A0A087WXE2 RPUSD2 RNA pseudouridylate synthase domain-containing protein 2 1 VELS(1)PGPPKPAGR;VELS(1)PGPPKPAGR;VELS(1)PGPPKPAGR 63.211999999999996 0.021872 143125000.0 275636.0 263035.0 276322.0 287209.0 315129.0 291178.0 342670.0 291773.0 277839.0 231662.0 True False 322295.73074084683 289147.3764622447 282910.5644370206 271117.6108741418 253381.73462245468 275908.1130904267 310209.8168840399 284114.26790904807 281901.8697552531 273660.4867646164 1.177721104538059 1.0565916178865422 1.033801290722546 0.9907079172424998 0.9258981361105154 1.0082131927498308 1.1335572064185528 1.0381998193017294 1.0301153560313783 1.0 18.062027616615048 -4.690903246728145 2.076020607650407 1.0206106240508528 1.2484282985812374 0.48574459592743824 0.04873823273417233 0.9432103314904096 3.7022779578124787 0.014526109472773425 0.4433244947619093 2.037495945875676e-05 4.690903246728145 0.2278176745303846 VELS(ph)PGPPKPAGR ddPTM_PC-9_Lapatinib_30min_R1 4 VELSPGPPKPAGR 13 1 A0A087WXE2;Q8IZ73-2;Q8IZ73 A0A087WXE2 RPUSD2 RNA pseudouridylate synthase domain-containing protein 2 1 VELS(1)PGPPKPAGR;VELS(1)PGPPKPAGR;VELS(1)PGPPKPAGR;VELS(1)PGPPKPAGR 64.52 0.019754 205861000.0 405743.0 360145.0 415026.0 396796.0 404127.0 405247.0 348057.0 359403.0 374196.0 316115.0 True False 399957.0304158467 359311.10637974256 380904.1643266896 425977.70151265385 380357.044404252 387915.5304868971 366077.68840401917 376102.1754451579 332050.10602143145 370755.05655324017 1.0787635214852778 0.9691333942148022 1.0273741587445944 1.1489464377716012 1.0258984676845075 1.046285205367638 0.9873842094219709 1.014422241308393 0.8956050636459743 1.0 18.500106843487686 -7.567810075579364 1.4694138638770136 0.957483072058844 1.0493225556510226 0.3484420456700046 0.05131414323295916 0.5007865659700645 2.0665666777896514 0.03731033436935154 0.016981522727399768 2.7051411100453307e-08 7.567810075579364 0.09183948359217864 VELSQLR ddPTM_PC-9_Lapatinib_30min_R1 1 VELSQLR 7 0 F2Z388;P42766 F2Z388 RPL35 60S ribosomal protein L35 0 115.46 0.037868 2694300.0 16765.0 16147.0 17071.0 17894.0 13301.0 15419.0 17266.0 16179.0 14742.0 17270.0 False True 16525.92802567554 16109.612613568732 15667.488275965625 19209.984452634126 12518.661330772144 14759.56531344454 18159.948996813167 16930.735404343333 13081.600719857894 20255.09648917148 0.8158898692242923 0.7953362563432392 0.7735084493101071 0.9484025150363476 0.6180499479459262 0.7286840287991276 0.8965619594318698 0.8358753271501139 0.6458424291807947 1.0 14.30599733715428 -10.958631824069121 6.058931113960496 1.0000810725510971 0.7873785538617374 0.3091710290368601 0.09665400546268932 0.00010528150049933505 9.804637514444358e-06 0.09308210967576956 0.02256715180663408 1.0999379237119607e-11 10.958631824069121 -0.21270251868935974 VENMSSNQDGNDS(ph)DEFM ddPTM_PC-9_Lapatinib_30min_R1 1 VENMSSNQDGNDSDEFM 17 0 Q86WR0-2;Q86WR0 Q86WR0-2 CCDC25 Coiled-coil domain-containing protein 25 1 VENMSSNQDGNDS(1)DEFM 134.56 4.1419999999999995e-06 0.0 4909.5 4381.5 6853.8 3410.7 4754.5 4265.5 4047.4 3684.8 5289.3 3820.0 True False 4839.489629707962 4371.3549059485595 6290.307020433091 3661.534255761663 4474.84965770665 4083.074508366154 4256.954567919706 3856.0092600237535 4693.563335201759 4480.281910169953 1.0801752494017465 0.9756874664573815 1.4039980399792469 0.8172553266012602 0.9987875199435614 0.9113432123763989 0.9501532834924274 0.8606621943299727 1.0476044653680543 1.0 12.129373797661104 -5.795208917830978 24.999940019420272 0.9365985446605494 1.1355281723299295 0.3980427388300003 0.11905026985594262 181.09895360239278 134068.72184899775 0.032104172015432295 0.04762100291487649 1.6024743332319833e-06 5.795208917830978 0.19892962766938016 VEPAS(ph)PPYYSEK ddPTM_PC-9_AZD4547_30min_R2 1 VEPASPPYYSEK 12 0 E7EU07;E7EUD1;A0A499FIV4;E9PFX5;A0A494C0D9;E9PFV2;P37231-3;P37231-2;P37231 E7EU07 PPARG Peroxisome proliferator-activated receptor gamma 1 VEPAS(1)PPYYSEK 145.52 0.00011111 22089000.0 52351.0 51601.0 68130.0 63363.0 60075.0 59610.0 62003.0 68707.0 60813.0 63138.0 True False 68997.52903155478 68280.01413744736 67226.55168464889 48755.639298591326 51734.62321998237 55882.57727667374 67521.14688427327 58089.911879792504 64027.451027799885 60927.55783771154 1.132451906497527 1.120675381726608 1.1033849717678745 0.8002231014815709 0.8491169686758865 0.917197065825685 1.1082201434057903 0.9534259035053158 1.0508783430700654 1.0 15.894807293447526 -5.560711213809412 23.450147518367494 0.9526440817584036 1.1229303170730476 0.44509788147787566 0.08449812424104775 79.17467786519464 49075.210957723786 0.024989096350483537 0.04328261392161931 2.749721986093383e-06 5.560711213809412 0.17028623531464393 VEPAS(ph)PPYYSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VEPASPPYYSEK 12 0 E7EU07;E7EUD1;A0A499FIV4;E9PFX5;A0A494C0D9;E9PFV2;P37231-3;P37231-2;P37231 E7EU07 PPARG Peroxisome proliferator-activated receptor gamma 1 VEPAS(0.98)PPYYS(0.02)EK;VEPAS(1)PPYYSEK;VEPAS(1)PPYYSEK;VEPAS(0.999)PPYYS(0.001)EK 215.34 8.976799999999999e-11 17079600.0 136031.0 154546.0 163523.0 164205.0 198061.0 142175.0 172444.0 154071.0 138205.0 138637.0 True False 159058.36156528172 169888.30552106837 167422.00848443125 155005.12620979262 159252.36884278493 134719.0927152167 156108.8559335558 150026.79950171857 140225.98666682787 163770.79065011189 0.971225460498032 1.0373541267442876 1.0222946828297361 0.9464760205069372 0.9724100873581276 0.8226075735509962 0.9532154990145623 0.9160778848668035 0.8562331909749016 1.0 17.321318542392746 -6.129085683845901 1.7927019810756375 0.9093166329062554 1.011749326850679 0.3754161387404852 0.05152412412018786 0.3375263858604227 2.1500950166518265 0.01687087970570827 0.02480242794859084 7.428725588816965e-07 6.129085683845901 0.10243269394442356 VEPAS(ph)PPYYSEK ddPTM_PC-9_Lapatinib_30min_R1 3 VEPASPPYYSEK 12 0 E7EU07;E7EUD1;A0A499FIV4;E9PFX5;A0A494C0D9;E9PFV2;P37231-3;P37231-2;P37231 E7EU07 PPARG Peroxisome proliferator-activated receptor gamma 1 VEPAS(1)PPYYSEK;VEPAS(1)PPYYSEK;VEPAS(0.998)PPYYS(0.002)EK 151.74 8.1305e-05 45434000.0 215895.0 248845.0 281327.0 241795.0 268514.0 276157.0 242056.0 278132.0 288685.0 214872.0 True False 212816.29770970636 248268.81469149163 258197.38001362447 259577.41090447461 252720.53443883575 264346.4088634089 254588.47529089602 291055.02809078566 256170.25531218117 252012.33890105764 0.8444677694660816 0.9851454725356295 1.0245426122369157 1.0300186571673664 1.0028101621566083 1.048942325666021 1.0102222629299504 1.1549237206399507 1.01649886044967 1.0 17.943134846398394 -3.898379967174286 1.010740953851504 1.0442750244782244 1.0447171736228642e-14 0.6492899388503697 0.04242183728202542 5.698412126184255 1.249201158958827 0.013418951261316425 9.86686449631279 0.00012636303050146458 3.898379967174286 -1.044275024478214 VEPEVLSTDTQT(ph)SPEPGTR ddPTM_PC-9_AZD4547_30min_R2 1 VEPEVLSTDTQTSPEPGTR 19 0 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 VEPEVLS(0.001)T(0.003)DT(0.009)QT(0.561)S(0.424)PEPGT(0.002)R 80.545 0.0059719 4385900.0 9988.6 8998.0 11696.0 16214.0 10719.0 13820.0 12105.0 13819.0 12571.0 12793.0 True False 13164.767024213274 11906.427534519697 11540.903397969356 12476.112803802844 9230.8518734081 12955.833215293247 13182.321549507738 11683.591079029096 13235.477395794858 12345.120963886151 1.0663943320381288 0.9644642259359153 0.9348554325008709 1.0106108186626839 0.7477328007081996 1.0494699284999836 1.0678163128632514 0.9464136571207148 1.0721221310437796 1.0 13.591653352372282 VEPEVLSTDTQT(ph)SPEPGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VEPEVLSTDTQTSPEPGTR 19 0 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 VEPEVLS(0.002)T(0.001)DT(0.019)QT(0.566)S(0.399)PEPGT(0.013)R 68.41 0.020703 5032300.0 11518.0 11069.0 11553.0 11443.0 14890.0 12509.0 10975.0 12603.0 10622.0 9540.4 True False 13467.769909130408 12167.85716752747 11828.46733499648 10801.885808706556 11972.41138875936 11853.006019164035 9935.368547880893 12272.184603982298 10777.32665515028 11269.998998235154 1.195010745896199 1.0796679901597965 1.049553539166133 0.9584637771838398 1.0623258609547526 1.0517308848936169 0.8815767019532779 1.0889250838357734 0.9562846151839033 1.0 13.460199766821674 -3.8785936235231455 0.8645890575922301 1.0009498010629272 1.8996967800595446 0.5164596922900985 0.057549055176877084 7.375458936418523 1.3517261193766308 0.0191681321105901 9.110623780888098 0.00013225325708248915 3.8785936235231455 0.8987469789966174 VEPEVLSTDTQTS(ph)PEPGTR ddPTM_PC-9_AZD4547_30min_R2 1 VEPEVLSTDTQTSPEPGTR 19 0 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 VEPEVLSTDTQT(0.036)S(0.962)PEPGT(0.002)R 197.94 6.2347e-15 4342500.0 20837.0 19693.0 26413.0 35161.0 31090.0 28928.0 25426.0 33529.0 22501.0 28166.0 True False 27462.732563475558 26058.3771323957 26062.746362052385 27055.17468203479 26773.69015246364 27119.12758697563 27688.864743311344 28347.86346977108 23690.356923298055 27179.91691306316 1.010405316959467 0.9587364529385877 0.9588972050729911 0.9954104999133233 0.985054157380287 0.9977634469493792 1.0187251429750903 1.0429709391843867 0.8716125586061686 1.0 14.730253425452585 -5.7887420679763455 24.804059435505625 0.9907968330253993 0.9742853165661556 0.009013346949673928 0.04435958963556877 892.4059542485197 810734.6248397956 0.012234438367244282 0.018152357940075994 1.6265144728616894e-06 5.7887420679763455 -0.016511516459243758 VEPEVLSTDTQTS(ph)PEPGTR ddPTM_PC-9_Lapatinib_30min_R1 2 VEPEVLSTDTQTSPEPGTR 19 0 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 VEPEVLSTDTQT(0.034)S(0.966)PEPGTR;VEPEVLSTDTQT(0.14)S(0.86)PEPGTR 214.46 1.1459000000000001e-27 8359100.0 23443.7 19938.8 20344.5 19267.6 20988.1 21345.7 17437.300000000003 17541.4 26720.0 18796.8 True False 23109.38853895195 19892.632933636218 18671.853742041043 20684.6035788294 19753.62122219223 20432.794170257035 18340.118072635825 18356.43748202906 23710.512225926144 22045.801834838374 1.048244410073251 0.9023320214282448 0.8469573428050335 0.9382558971451013 0.896026434882315 0.9268337946305791 0.8319097762937088 0.8326500265016847 1.0755114467398086 1.0 14.428216330175482 -8.269152640707619 24.99085810938506 1.0377557353606206 0.9003981454742425 0.4268621138805624 0.0624506235691727 604.9697538494138 1960067.1124812223 0.056637162272517805 0.015684633901838194 5.380806310373666e-09 8.269152640707619 -0.13735758988637814 VEPGLGADNSVVR ddPTM_PC-9_Lapatinib_30min_R1 1 VEPGLGADNSVVR 13 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 91.469 0.023492 8856500.0 19693.0 21071.0 27144.0 23745.0 19492.0 21408.0 19278.0 17290.0 23205.0 13956.0 False True 19412.174208746103 21022.21139409837 24912.32509887006 25491.286510997954 18345.51888274646 20492.429744485424 20276.120512021567 18093.356520248224 20591.408540517074 16368.27600479891 1.185963274510692 1.2843265465425315 1.5219883322816754 1.557359278614579 1.1207972591229434 1.2519601782421912 1.2387450276423089 1.105391704962914 1.2580071679192122 1.0 13.998614756932367 -6.281847693859563 24.90653868539864 1.1760400374891076 1.3896591003158327 0.4390948463799049 0.12396321322153744 814.5041790598715 994027.5566332388 0.040337107430581914 0.045790486849539694 5.225794243469317e-07 6.281847693859563 0.21361906282672516 VEPGSLES(ph)SPGLGR ddPTM_PC-9_Lapatinib_30min_R1 1 VEPGSLESSPGLGR 14 0 Q92615;H0Y4V9 Q92615 LARP4B La-related protein 4B 1 VEPGSLES(0.62)S(0.38)PGLGR 163.33 3.7654000000000003e-13 0.0 7564.5 6787.1 10844.0 9817.1 10197.0 11409.0 8483.4 8482.0 9872.0 8032.0 True False 7456.628842840595 6771.384886948178 9952.448179050512 10539.082282885569 9597.232508073348 10921.063665677984 8922.628942405003 8876.104685063363 8760.111403231389 9420.320498032737 0.7915472562104205 0.7188062113557876 1.0564872162395005 1.1187604800798938 1.0187798292083114 1.1593091411230276 0.9471682990263793 0.9422295862350942 0.9299164932934902 1.0 13.201560428688765 -5.262087198858992 24.999965362482346 1.0251500213419946 0.7551767157492044 0.6812275524904406 0.0728620085998452 32.232476722480044 1243941.8853511845 0.020440044096958217 0.04708466744613861 5.469061425266025e-06 5.262087198858992 -0.2699733055927902 VEPS(ph)SQSPGRSPR ddPTM_PC-9_Lapatinib_30min_R1 1 VEPSSQSPGRSPR 13 1 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 VEPS(0.286)S(0.286)QS(0.284)PGRS(0.145)PR 121.45 0.00095103 15548000.0 33763.0 20440.0 31058.0 23260.0 23346.0 25131.0 19862.0 20670.0 29393.0 16660.0 True False 33281.5334286241 20392.67243582985 28504.531127346996 24970.61799308539 21972.83418000198 24056.20571322232 20890.357174487606 21630.403659544874 26082.45081798827 19539.658801945396 1.7032811967684176 1.0436555030223724 1.4588039339002707 1.2779454465499307 1.124524967540085 1.2311476856917916 1.0691259958135877 1.1070000698984221 1.334846789412283 1.0 14.254117654990903 -4.750862793504403 24.999677162133096 1.1940531048811005 1.7032822623092594 0.5651230379873351 0.13661080046826715 342.8860082982411 810419.8592800715 0.033415237662412146 0.4710223677160111 1.7747500884705482e-05 4.750862793504403 0.5092291574281589 VEPSSQS(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VEPSSQSPGR 10 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 VEPS(0.047)S(0.028)QS(0.926)PGR 70.54 0.035508 15590000.0 27175.0 29229.0 29314.0 34483.0 35572.0 24337.0 23024.0 27163.0 22523.0 20797.0 True False 31775.19076928449 32130.661952268572 30012.956933964084 32551.029305394386 28601.921955738617 23060.724877160064 20843.000040675135 26450.00003157747 22852.35626567029 24567.331471038586 1.2933920318835992 1.3078612949943744 1.2216612524378205 1.3249721217694097 1.1642258333778026 0.9386743897824394 0.8484030943794644 1.0766330100914006 0.9301928576414573 1.0 14.584453538731816 -6.605305499641695 3.4208272677773977 0.9566091517675145 1.2818133907475098 0.8692110968858147 0.06026930679577829 0.08184674197414399 1.9108621043229463 0.020939617915665815 0.021148939886343122 2.48138698703935e-07 6.605305499641695 0.3252042389799953 VEPSSQS(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 2 VEPSSQSPGR 10 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 VEPS(0.005)S(0.008)QS(0.987)PGR;VEPS(0.022)S(0.012)QS(0.966)PGR 87.831 0.010376 40574000.0 18128.1 25532.0 35040.0 23254.4 26172.0 24069.0 27324.0 25006.0 27112.0 20799.9 True False 17869.58996971361 25472.8822226814 32159.146458311498 24964.606150404317 24632.61441613175 23039.624977579384 28738.7030226412 26167.87004889111 24058.36105798313 24395.135000875383 0.7325062955819832 1.0441787767014752 1.3182606473445428 1.0233436359138204 1.0097347038763198 0.9444352317276637 1.1780505835122435 1.0726675645759745 0.9861950367202243 1.0 14.574305846603286 -4.768495910042729 5.52817606715792 1.072359812094015 0.7179251808632271 0.4803630459615398 0.10349370261362356 0.12457753824195396 12.154911222199807 0.02649399086620339 0.16730467149390038 1.704135367891585e-05 4.768495910042729 -0.3544346312307879 VEPSSQS(ph)PGRSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VEPSSQSPGRSPR 13 1 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 VEPS(0.062)S(0.095)QS(0.644)PGRS(0.199)PR 118.52 0.001168 17723000.0 17272.0 11215.0 21769.0 25265.0 26493.0 27112.0 24292.0 25461.0 22949.0 19257.0 True False 20195.808462450103 12328.351082647096 22288.05551939224 23849.48396023517 21301.886831591793 25690.198992051748 21990.885901150126 24792.675728159407 23284.585709757444 22748.14166167189 0.8878003646547451 0.5419498113737795 0.9797747812053218 1.04841460524307 0.9364231658308654 1.1293317658266961 0.9667113133114669 1.0898769709146103 1.0235818844485836 1.0 14.473461073212613 -5.40290316532691 6.378578586460615 1.0281978129194342 0.7172535488934894 0.6350315396314763 0.09358503231731091 0.124306192173003 5.962177279017559 0.022402466987838612 0.04716375972634228 3.954547848216408e-06 5.40290316532691 -0.3109442640259449 VEPSSQSPGRS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 VEPSSQSPGRSPR 13 1 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 VEPS(0.033)S(0.033)QS(0.083)PGRS(0.85)PR;VEPSSQSPGRS(1)PR;VEPSSQS(0.005)PGRS(0.995)PR 121.21 9.472e-05 92233000.0 50826.0 49683.0 95568.0 143313.0 116966.0 91204.0 73512.0 107334.0 80227.0 97993.0 True False 66987.61075352534 65742.05814598147 94300.70587697804 110274.40201377806 100727.28988012417 85500.99946219998 80054.42558838602 90747.99658994944 84467.63543333342 94562.29489674768 0.7083966270770917 0.6952248591022991 0.9972336857935261 1.1661561527687794 1.0651950652224338 0.9041764432172283 0.8465787095776094 0.9596636448918349 0.8932485778349966 1.0 16.52897742771276 -5.260092584063166 24.82229614875298 0.979947392428021 0.7018107117121355 0.6236944077646857 0.08613077279961384 74.71829413742651 1377064.7103321154 0.02550043175734602 0.060355909199606636 5.494237337459008e-06 5.260092584063166 -0.2781366807158855 VEPSSQSPGRS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VEPSSQSPGRSPR 13 1 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 VEPS(0.004)S(0.057)QS(0.005)PGRS(0.934)PR;VEPSSQS(0.011)PGRS(0.989)PR 130.66 6.3155e-05 79777000.0 37882.0 33516.0 48930.0 62670.0 67229.0 63765.0 66246.0 69004.0 59761.0 41316.0 True False 44294.67439639505 36843.24698047259 50096.67676805836 59158.80307888139 54055.96005741457 60421.05114813294 59970.69930049356 67192.71811578149 60634.89156829562 48806.263742723975 0.9075612636502726 0.7548876753747652 1.0264394962117287 1.2121149734126242 1.1075619379996737 1.2379773929558477 1.22875005586622 1.3767232515477803 1.2423588064008497 1.0 15.57477869312987 -5.549154311394835 2.7822869624625866 1.2167499079726152 0.8313442938748625 0.6846532358466363 0.099783361239582 0.13999999034664473 2.1804697990016217 0.028072398294602882 0.06021252967829355 2.8238764306534872e-06 5.549154311394835 -0.38540561409775265 VEPSSQSPGRS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 VEPSSQSPGRSPR 13 1 X6RM00;G8JLD3;X6RLX0;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;Q8IUD2-5;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 VEPS(0.024)S(0.084)QS(0.295)PGRS(0.598)PR;VEPSSQSPGRS(1)PR;VEPS(0.006)S(0.013)QS(0.02)PGRS(0.962)PR 135.94 2.5069e-05 80282000.0 78941.0 52501.0 76085.0 55814.0 58944.0 57015.0 42263.1 42699.8 64562.0 43391.0 True False 77815.28686399359 52379.437160151814 69829.58499659327 59918.74775004589 55477.02980836279 54576.60135845645 44451.27652306349 44683.78859128374 57290.347692000076 50891.07653512683 1.5290556255040648 1.0292460039432978 1.3721380986781526 1.1773920268455678 1.0901131118747425 1.0724198636432016 0.8734591513775827 0.8780279694111285 1.1257444643061587 1.0 15.635125089541347 -6.3729872002681205 1.2017037954285688 0.9637556250942139 1.2933848771058425 0.5136552839346693 0.13578028939161502 0.3805168756237659 1.137591477917389 0.05603172556855561 0.07328001058193015 4.236554520389154e-07 6.3729872002681205 0.3296292520116286 VEQATKPS(ph)FESGR ddPTM_PC-9_AZD4547_30min_R2 2 VEQATKPSFESGR 13 1 P38159;P38159-2;H0Y6E7;H3BT71 P38159 RBMX RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed 1 VEQAT(0.012)KPS(0.985)FES(0.003)GR;VEQATKPS(1)FESGR 143.93 0.00042860000000000006 29293500.0 25394.2 21368.6 30102.7 35528.0 34408.0 34084.0 27833.0 38682.0 33938.0 29276.0 True False 33469.027367827 28275.582064251797 29703.518529245222 27337.568502128255 29631.043125312597 31952.722091899792 30310.08308033449 32704.585723931097 35731.89339419981 28251.05615092089 1.184700040558874 1.000868141466991 1.051412675355041 0.9676653628836861 1.048847270240788 1.1310275241111027 1.0728831842043005 1.1576411709784888 1.2647984982690663 1.0 14.786017182483087 -7.076311573484442 1.544863711182591 1.145664487126732 1.0446130135243954 0.14468505626163752 0.08283645643036386 0.6303560707157728 3.0082996682027274 0.042264136364195286 0.029576596675809554 8.388579533738079e-08 7.076311573484442 -0.10105147360233668 VEQATKPS(ph)FESGR ddPTM_PC-9_Lapatinib_30min_R1 1 VEQATKPSFESGR 13 1 P38159;P38159-2;H0Y6E7;H3BT71 P38159 RBMX RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed 1 VEQAT(0.173)KPS(0.827)FESGR 61.18600000000001 0.025685000000000003 13483000.0 33052.0 33806.0 44102.0 34191.0 38435.0 38196.0 42894.0 41264.0 35124.0 34098.0 True False 32580.672419005532 33727.72428403443 40476.10379864311 36705.520197832426 36174.328866117365 36562.44611922485 45114.84143804608 43181.27608163812 31167.96524788285 39991.793867270935 0.814683945589882 0.843366126460184 1.0121102327387352 0.917826300056823 0.9045437918133059 0.914248714138011 1.128102469916155 1.0797534170373246 0.7793590192859676 1.0 15.287416375510478 -7.037479021245157 24.8263997200092 1.0059821203109789 0.9034842758652954 0.1856382561626061 0.09759892672348282 889.4030005265487 589144.8333048319 0.037936345824359514 0.029393508475182344 9.1732024581176e-08 7.037479021245157 -0.10249784444568344 VEQHVVDGK ddPTM_PC-9_AZD4547_30min_R2 1 VEQHVVDGK 9 0 Q9Y3I0 Q9Y3I0 RTCB tRNA-splicing ligase RtcB homolog 0 85.81299999999999 0.010194 2741700.0 56593.0 44652.0 77281.0 97978.0 86787.0 71897.0 54118.0 84544.0 59622.0 67141.0 False True 74588.39679247355 59084.88578254877 76256.20344549157 75390.6858450101 74738.12310266537 67401.26922430824 58934.39715954229 71479.66742784838 62773.497199274585 64790.41402612995 1.1512258088425253 0.9119386975783156 1.1769673738268978 1.1636086445535765 1.153536741909436 1.0402969364746664 0.90961599868422 1.1032444922951203 0.9688701352326297 1.0 15.983492756548452 -6.97342443961436 8.532334581445044 0.9999024218064193 1.1061064878125315 0.29990451742212765 0.08373235082536537 0.328084301972815 92.61819669550005 0.03025644836586583 0.026468994507892855 1.0631035304222446e-07 6.97342443961436 0.10620406600611221 VEQHVVDGK ddPTM_PC-9_Lapatinib_30min_R1 1 VEQHVVDGK 9 0 Q9Y3I0 Q9Y3I0 RTCB tRNA-splicing ligase RtcB homolog 0 76.143 0.020936 2442700.0 80690.0 85993.0 85565.0 70365.0 89723.0 75993.0 71221.0 73719.0 78971.0 70628.0 False True 79539.34580326636 85793.88849189419 78530.17599045145 75539.87683075898 84445.66954220503 72742.95653833533 74908.47489297063 77144.25386444075 70076.45437850348 82835.95569410568 0.9602031525656208 1.0357083198111636 0.9480204016773284 0.911921353448381 1.019432549967114 0.8781567850434238 0.9042990361527374 0.9312894771120516 0.8459666311725775 1.0 16.337969498022296 -6.770560060475829 24.999691424266352 0.9071702688646761 0.9734170807771815 0.2872539627190759 0.04939024520011249 245.9501077969441 674142.553121155 0.01678577993859216 0.015007082056977645 1.6960550312017014e-07 6.770560060475829 0.06624681191250537 VEQIEAGT(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 1 VEQIEAGTPGR 11 0 Q16881;Q16881-5;A0A182DWI3;Q16881-2;F8W809;Q16881-3;Q16881-6;Q16881-4;A0A087WSW9;E9PIR7;A0A087WSY9;Q16881-7;E2QRB9 Q16881 TXNRD1 Thioredoxin reductase 1, cytoplasmic 1 VEQIEAGT(1)PGR 99.834 0.010753 2691000.0 9609.9 18381.0 18859.0 20071.0 17866.0 19958.0 19693.0 17770.0 16205.0 13859.0 True False 9472.861063760172 18338.43992382528 17308.485817845216 21547.088294893234 16815.15700590745 19104.44286437033 20712.607181410967 18595.659072574377 14379.822253784918 16254.509684043289 0.5827835627093373 1.1282062812283868 1.064842074863482 1.3256067832083276 1.03449180152229 1.1753318454831498 1.2742683466942162 1.1440307603267386 0.8846666268808642 1.0 13.988552417456027 -4.761436356207667 13.276124007682647 1.1285514372944936 0.582413172270308 0.6254275121781094 0.123046176079083 0.03423113651432977 588.8278363787722 0.029992499402794845 0.16744502626198657 1.7320628377297773e-05 4.761436356207667 -0.5461382650241856 VEQMPQAS(ph)PGLAPR ddPTM_PC-9_AZD4547_30min_R2 4 VEQMPQASPGLAPR 14 0 H0Y6J8;Q8N3F8 H0Y6J8;Q8N3F8 MICALL1 MICAL-like protein 1 1 VEQMPQAS(1)PGLAPR;VEQMPQAS(1)PGLAPR;VEQMPQAS(1)PGLAPR;VEQMPQAS(1)PGLAPR 151.8 9.4148e-05 57681000.0 86806.0 113245.0 193562.0 254213.0 249154.0 223664.0 197923.0 289438.0 206214.0 242983.0 True False 114408.50232303403 149849.23162332538 190995.24140883572 195608.12040169808 214563.26781109403 209678.254722529 215537.76357234397 244712.00772357092 217114.05104577504 234476.23912826902 0.4879321791767883 0.6390806683885404 0.8145611773666872 0.8342342965279806 0.9150746728486987 0.8942409495395633 0.9192307262077636 1.0436537562755024 0.9259533155809613 1.0 17.839082207716324 -4.479370725450452 0.5556783023108702 0.9732651830901873 6.761322628220164e-21 0.9430367250323867 0.03802065322722265 1.167158476013092 0.21517154196945723 0.020736105449329276 0.7887719975710822 3.316112644049153e-05 4.479370725450452 -0.9732651830901873 down VEQMPQAS(ph)PGLAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VEQMPQASPGLAPR 14 0 H0Y6J8;Q8N3F8 H0Y6J8;Q8N3F8 MICALL1 MICAL-like protein 1 1 VEQMPQAS(1)PGLAPR;VEQMPQAS(1)PGLAPR;VEQMPQAS(1)PGLAPR 101.2 0.0017687999999999998 59209200.0 118800.7 164440.0 210008.0 207674.0 240473.0 209480.0 228157.0 233448.0 190814.0 170615.0 True False 138911.31208921928 180764.5164538995 215015.3871797752 196038.69906819207 193354.0418998747 198494.5000315358 206544.3172463653 227320.23735860147 193604.29376537804 201546.1489124036 0.6892283124178831 0.896888962797616 1.0668295491630835 0.9726740010963684 0.9593536911683221 0.9848588082812036 1.0247991259616378 1.1278818205422514 0.9605953515366982 1.0 17.620750691274736 -4.852260804797118 2.6927644961447847 1.012630166452087 0.6518187438823917 0.7945495197188182 0.05022567375002215 0.16939895978774788 1.8548614599442885 0.013513373085755833 0.12937109362431476 1.4052034105869217e-05 4.852260804797118 -0.36081142256969523 VEQMPQAS(ph)PGLAPR ddPTM_PC-9_Lapatinib_30min_R1 4 VEQMPQASPGLAPR 14 0 H0Y6J8;Q8N3F8 H0Y6J8;Q8N3F8 MICALL1 MICAL-like protein 1 1 VEQMPQAS(1)PGLAPR;VEQMPQAS(1)PGLAPR;VEQMPQAS(1)PGLAPR;VEQMPQAS(1)PGLAPR 146.1 0.00019171 98338000.0 292174.0 272876.0 309590.0 282003.0 253592.0 237531.0 187643.0 177869.0 256414.0 148342.0 True False 288007.5451818499 272244.172387451 284136.70525196 302742.4413544304 238676.21714105463 227372.35284180555 197358.23639574938 186133.44308270907 227533.95516087674 173982.71704670935 1.6553802013824637 1.5647771055004347 1.6331317850133211 1.7400719249208687 1.3718386584167261 1.3068674676506093 1.1343554103869085 1.0698386957179062 1.3077963088700955 1.0 17.40858447436483 -6.666551163736563 1.7010077692121648 1.1389756718723414 1.6417981456758668 0.8565041204996146 0.09396043456433681 0.1270446310040564 0.7584338647642278 0.037473001661518276 0.03674262632989351 2.1550077496109236e-07 6.666551163736563 0.5028224738035254 VERLSSGPEQITLEASSTEGHPGAPS(ph)PQHTDQTEAFQK ddPTM_PC-9_AZD4547_30min_R2 1 VERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQK 38 1 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 VERLS(0.089)S(0.089)GPEQIT(0.154)LEAS(0.154)S(0.154)T(0.154)EGHPGAPS(0.171)PQHT(0.027)DQT(0.006)EAFQK 45.856 0.0021399 13733000.0 1595.3 1666.1 8178.6 12829.0 9919.2 10741.0 5071.3 11649.0 9138.9 10200.0 True False 2102.572215698639 2204.6342426387264 8070.146420197696 9871.472256074176 8542.090297855175 10069.363572030741 5522.635875590136 9848.914717389822 9621.96359656587 9842.901104638373 0.21361305913231435 0.22398215924366177 0.8198951035274261 1.0029027164991364 0.8678427434193966 1.0230076950875437 0.5610780619331476 1.000610959379508 0.9775536190271802 1.0 13.264867884007986 -5.288106411681056 4.170186128981492 0.9062066775466875 0.20526391267223362 0.8200584554029071 0.12941919060951682 0.07646880838027763 3.141600163657606 0.03404473898410054 0.08315950194646407 5.151024177191044e-06 5.288106411681056 -0.7009427648744538 down VERPPS(ph)PFSMAPQASLPPVPPR ddPTM_PC-9_AZD4547_30min_R2 4 VERPPSPFSMAPQASLPPVPPR 22 1 A0A1B0GW38;A0A0U1RQX8;P22681 A0A1B0GW38 CBL E3 ubiquitin-protein ligase CBL 1 VERPPS(0.954)PFS(0.046)MAPQASLPPVPPR;VERPPS(0.986)PFS(0.014)MAPQASLPPVPPR;VERPPS(0.996)PFS(0.004)MAPQASLPPVPPR;VERPPS(0.995)PFS(0.005)MAPQASLPPVPPR 91.889 9.4467e-05 110221000.0 94027.0 100879.0 140699.0 183846.0 173044.0 150923.0 123865.0 161080.0 136771.0 136011.0 True False 123925.63011690327 133486.16395363543 138833.2393289064 141463.14509238536 149019.82755686462 141485.7609516428 134888.74504170008 136188.78725016362 144000.4358364696 131249.2962885262 0.9442003395163104 1.0170428926353396 1.0577827329733513 1.0778202176521081 1.1353952498859372 1.0779925298846076 1.0277292820311452 1.0376344186316921 1.0971520603044795 1.0 17.001950162024905 -4.845422926508556 1.829834601157404 1.0681262274221772 0.9143403836231041 0.5162825870838826 0.03579494722915496 0.6011261146994806 2.3382051232830117 0.010228543803241409 0.15451631159212914 1.4275031442035646e-05 4.845422926508556 -0.15378584379907312 VERPPS(ph)PFSMAPQASLPPVPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VERPPSPFSMAPQASLPPVPPR 22 1 A0A1B0GW38;A0A0U1RQX8;P22681 A0A1B0GW38 CBL E3 ubiquitin-protein ligase CBL 1 VERPPS(0.981)PFS(0.019)MAPQASLPPVPPR;VERPPS(0.989)PFS(0.011)MAPQASLPPVPPR;VERPPS(0.958)PFS(0.039)MAPQAS(0.003)LPPVPPR 81.003 0.00069596 47994200.0 71939.0 66121.0 74361.0 88699.0 97615.0 71557.0 83232.0 73716.0 68483.0 59702.6 True False 84116.85183998373 72685.05590153433 76134.04825566309 83729.48259603798 78488.04148514083 67804.42495110095 75347.66241250302 71781.0331085582 69484.4343178926 70526.20877447833 1.1927034403474628 1.0306105654134812 1.079514262550493 1.1872108830318635 1.112891829137194 0.96140748424347 1.0683639986014597 1.0177923123316102 0.985228548724106 1.0 16.10587186744999 -6.739994571467083 23.02603071653445 1.0115333741724326 1.1170072779232458 0.5527282356706574 0.05113900078771275 81.57898671529469 87593.41377799388 0.01704310160382564 0.017020564616049637 1.819723604392304e-07 6.739994571467083 0.10547390375081322 VERPPS(ph)PFSMAPQASLPPVPPR ddPTM_PC-9_Lapatinib_30min_R1 5 VERPPSPFSMAPQASLPPVPPR 22 1 A0A1B0GW38;A0A0U1RQX8;P22681 A0A1B0GW38 CBL E3 ubiquitin-protein ligase CBL 1 VERPPS(0.957)PFS(0.043)MAPQASLPPVPPR;VERPPS(0.949)PFS(0.051)MAPQASLPPVPPR;VERPPS(0.92)PFS(0.08)MAPQASLPPVPPR;VERPPS(0.999)PFS(0.001)MAPQASLPPVPPR;VERPPS(0.999)PFS(0.001)MAPQASLPPVPPR 126.04 2.1314e-06 84366000.0 161085.0 148747.0 155352.0 135295.0 176108.0 159601.0 150781.0 140188.0 159664.0 126718.0 True False 158787.89836062863 148402.58546048834 142579.55823606165 145245.04563088904 165749.67368164947 152775.23727810243 158587.702402901 146701.64626145485 141680.95898354315 148621.03745887885 1.0684079527069834 0.9985301408055979 0.9593497708930421 0.9772845629009695 1.1152504148513285 1.027951627106445 1.067060929693616 0.987085333070999 0.953303525570827 1.0 17.181278819717186 -7.9574744974839415 11.965320046384868 0.97449819940352 1.0276608106341243 0.21052365664941486 0.04476278106584241 1.2859082872461665 359.15168692508985 0.02615303735373709 0.012549570688596431 1.1028729945399067e-08 7.9574744974839415 0.053162611230604284 VERPPSPFS(ph)MAPQASLPPVPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VERPPSPFSMAPQASLPPVPPR 22 1 A0A1B0GW38;A0A0U1RQX8;P22681 A0A1B0GW38 CBL E3 ubiquitin-protein ligase CBL 1 VERPPS(0.361)PFS(0.62)MAPQAS(0.019)LPPVPPR 74.324 0.0014646 32548000.0 45984.0 49696.0 52363.0 68470.0 70319.0 59883.0 65226.0 58165.0 61486.0 54666.0 True False 53768.18297460084 54629.490450577796 53611.532507783355 64633.84788273503 56540.49673916515 56742.630062003365 59047.321084654104 56638.230380911686 62385.116429916234 64576.51306418207 0.832627536286468 0.8459653186334478 0.8302017244953949 1.000887858694011 0.8755582185580384 0.8786883554026419 0.9143776627574711 0.8770716734831967 0.9660651136104573 1.0 15.97872192144857 -1.5228804623673848 0.035676095946462205 1.3299001014068073 0.23077876321586313 0.4696377299622698 0.04525276499838168 935.8986462310789 2.5602701122324314 23.100534543952456 65.9858551749044 0.029999881388063327 1.5228804623673848 -1.0991213381909442 VES(ph)GYFSLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VESGYFSLEK 10 0 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 VES(0.953)GY(0.031)FS(0.016)LEK 93.429 0.006799600000000001 7180200.0 12517.0 15556.0 17254.0 24366.0 33246.0 22946.0 26494.0 31516.0 22041.0 22281.0 True False 14635.880877981013 17100.296873977542 17665.400796159396 23000.85201563783 26731.684958407917 21742.671365875598 23984.296520050695 30688.73839396223 22363.307927524696 26320.36892370105 0.556066707135007 0.6496982213109866 0.6711684341267724 0.8738803047295415 1.0156272898719318 0.8260777585946634 0.911244693779852 1.165969158066304 0.8496578445519779 1.0 14.683892090532323 -5.7661529865648395 2.0568750367609643 0.9626400235856605 0.6018539617635131 0.7304165430928348 0.09187645665430007 0.16676946362870523 1.4399399850309256 0.02822462471644043 0.054847417715415375 1.7133536473814239e-06 5.7661529865648395 -0.36078606182214734 VESEES(ph)GDEEGKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VESEESGDEEGKK 13 1 Q15435;B5MBZ8;H7C003;Q15435-3;H7C118;C9JRC4;C9JD73 Q15435 PPP1R7 Protein phosphatase 1 regulatory subunit 7 1 VESEES(1)GDEEGKK 182.57 5.5007e-27 0.0 28334.0 30814.0 17813.0 22651.0 26620.0 17032.0 26058.0 17451.0 16875.0 20436.0 True False 33130.386577991056 33873.010277368485 18237.7294761787 21381.93790553282 21404.002093268926 16138.811936877606 23589.59759641734 16992.92974086289 17121.764950636512 24140.885028713015 1.3723766356778546 1.4031387099967603 0.7554706239844505 0.88571474824147 0.8866287241669534 0.6685261090337908 0.9771637439290243 0.703906659621286 0.709243465194917 1.0 14.559190947238497 -5.258609481932111 24.994578586452487 0.8172107861483285 1.387757737450463 0.8101273059817635 0.10926820799366162 89.04425463056837 786457.4381544952 0.027011937356372966 0.06525173256940804 5.513032060298087e-06 5.258609481932111 0.5705469513021345 VESEES(ph)GDEEGKK ddPTM_PC-9_Lapatinib_30min_R1 1 VESEESGDEEGKK 13 1 Q15435;B5MBZ8;H7C003;Q15435-3;H7C118;C9JRC4;C9JD73 Q15435 PPP1R7 Protein phosphatase 1 regulatory subunit 7 1 VES(0.001)EES(0.999)GDEEGKK 101.45 0.002936 5333500.0 26261.0 48209.0 30699.0 42307.0 50625.0 45727.0 49714.0 51914.0 40007.0 47327.0 True False 25886.513324322415 48097.37502245213 28175.046721566923 45418.39791201474 47647.337032579504 43771.362804843295 52287.947667529836 54326.1139613746 35500.990367613274 55507.40889073647 0.4663614072722924 0.8665036971394103 0.507590739409726 0.8182402821471736 0.8583959868559327 0.788567934976122 0.9419994323722806 0.9787182476543412 0.6395721053651627 1.0 15.760392728607629 -5.914475082189048 6.944181601979299 0.8640704871117775 0.6397026885921052 0.39942809791625933 0.1388807661014889 0.23381232980864414 15.858203236271848 0.03710760197411627 0.0553549621941648 1.217656854365859e-06 5.914475082189048 -0.22436779851967226 VESEIKVPDVELK ddPTM_PC-9_Lapatinib_30min_R1 1 VESEIKVPDVELK 13 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 90.861 0.0070006 2493800.0 16092.0 14419.0 18433.0 16459.0 15607.0 14614.0 17907.0 13872.0 15881.0 14797.0 False True 15862.525129088623 14385.613691400726 16917.50989343767 17669.449765614456 14689.026944542582 13988.993286897881 18834.136840376075 14516.54376222576 14092.314545656169 17354.64173423685 0.9140220450529605 0.8289202342345741 0.9748118199445848 1.0181397021153458 0.8464033524566742 0.8060663827649468 1.085250685597301 0.8364646176237591 0.8120199057670643 1.0 14.083033962314692 VESGDPSLHPPPS(ph)PGTPSATPASPPASATPSQR ddPTM_PC-9_AZD4547_30min_R2 3 VESGDPSLHPPPSPGTPSATPASPPASATPSQR 33 0 H3BLU1;Q4KMQ1 H3BLU1 TPRN Taperin 1 VES(0.001)GDPS(0.01)LHPPPS(0.926)PGT(0.058)PS(0.003)AT(0.001)PAS(0.001)PPASATPSQR;VESGDPS(0.001)LHPPPS(0.85)PGT(0.112)PS(0.013)AT(0.016)PAS(0.004)PPAS(0.002)AT(0.002)PS(0.001)QR;VESGDPSLHPPPS(0.916)PGT(0.083)PS(0.001)ATPASPPASATPSQR 113.34 2.4358e-22 33641300.0 14388.3 8125.800000000001 58527.0 101787.0 74206.0 55275.0 37239.8 69745.0 48031.0 62298.0 True False 18963.480104768205 10752.305941320315 57750.89373913753 78321.57974347348 63903.77778879758 51818.64551196339 40554.07005694822 58967.512830659645 50569.82060277006 60116.965982035406 0.3154430666117617 0.17885643038827673 0.9606421880371521 1.3028199022365519 1.0629907338952165 0.8619637512553149 0.6745861071742524 0.9808797211802197 0.8411904988332529 1.0 15.875484579869525 -5.26486342396387 24.823555166048067 0.9620878400102103 0.24714970536997666 0.7689730768640871 0.15642842299825202 121.01801845729022 877361.2010741434 0.04531463481358039 0.10090300795008875 5.434211986057825e-06 5.26486342396387 -0.7149381346402337 VESGDPSLHPPPSPGTPSATPAS(ph)PPASATPSQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VESGDPSLHPPPSPGTPSATPASPPASATPSQR 33 0 H3BLU1;Q4KMQ1 H3BLU1 TPRN Taperin 1 VESGDPSLHPPPSPGT(0.002)PS(0.029)AT(0.029)PAS(0.445)PPAS(0.164)AT(0.27)PS(0.062)QR 70.632 8.1858e-06 6963900.0 5868.2 5757.0 16365.0 14724.0 21302.0 21294.0 16646.0 17914.0 13048.0 13077.0 True False 6861.570357766887 6328.516913312468 16755.203664608118 13899.062015852072 17128.026017686487 20177.305154055404 15069.170373396384 17443.776481451947 13238.802315609182 15447.756582524959 0.44417908329348843 0.4096722316605835 1.0846366962800404 0.8997463121328035 1.1087710973554767 1.3061641052061033 0.9754924796292528 1.129210988551241 0.8570048501790466 1.0 13.915109715913951 -5.260676745320082 24.943709098635868 1.0536594601590992 0.42692559446348405 0.8077361624278052 0.12058631663492869 24.760921762894476 809824.772295887 0.031482117906371364 0.0739581038188575 5.486852111172733e-06 5.260676745320082 -0.6267338656956152 VESGDPSLHPPPSPGTPSATPAS(ph)PPASATPSQR ddPTM_PC-9_Lapatinib_30min_R1 1 VESGDPSLHPPPSPGTPSATPASPPASATPSQR 33 0 H3BLU1;Q4KMQ1 H3BLU1 TPRN Taperin 1 VESGDPSLHPPPS(0.002)PGT(0.029)PS(0.05)AT(0.05)PAS(0.324)PPAS(0.232)AT(0.156)PS(0.156)QR 69.20100000000001 1.1632e-05 9405800.0 30572.0 18476.0 55750.0 27481.0 40560.0 40700.0 24556.0 23469.0 49898.0 22740.0 True False 30136.037673781844 18433.21995716206 51166.45020122335 29502.04441392859 38174.34054402813 38959.35587633391 25827.389526569226 24559.455417796762 44277.96179076577 26670.578700854636 1.129935649758367 0.6911443566303787 1.918460441939483 1.1061643897881834 1.431327792778822 1.4607615497704027 0.9683850439188861 0.92084448910026 1.6601800166168468 1.0 14.702961508517603 -11.124728661961443 6.10018666580631 0.9990840701549876 1.2458440957299541 0.044737529800812026 0.35041774738811515 0.004294924019087047 0.0002803228813351679 0.3338306571322384 0.08067866665491821 7.503628738193353e-12 11.124728661961443 0.24676002557496657 VESGYFS(ph)LEK ddPTM_PC-9_AZD4547_30min_R2 2 VESGYFSLEK 10 0 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 VES(0.001)GY(0.025)FS(0.975)LEK;VES(0.019)GYFS(0.981)LEK 127.56 0.00030887 23997000.0 33690.0 31612.0 43374.0 64347.0 76750.0 64333.0 61147.0 65554.0 66311.0 59143.0 True False 44402.71920446758 41829.96079364711 42798.83241993185 49512.79330123978 66094.58730143399 60310.24734004784 66588.96454256505 55424.13558106039 69816.06408341041 57072.421571728155 0.7780065744829595 0.7329277371046111 0.7499039157843097 0.8675432360796624 1.1580827566317096 1.0567318799369747 1.1667450356715034 0.9711193962815086 1.2232889749678162 1.0 15.800506157131995 -6.080289450636215 3.4353736982975325 1.0957064469444358 0.7549545257920112 0.8196158926730461 0.07339922343611893 0.09154430867867287 2.070530610029826 0.020754815862746807 0.028568043812045727 8.31209597952975e-07 6.080289450636215 -0.3407519211524246 VESGYFS(ph)LEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VESGYFSLEK 10 0 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 VES(0.015)GYFS(0.985)LEK;VES(0.01)GYFS(0.989)LEK;VESGYFS(1)LEK 109.0 0.0019473 26753500.0 98739.0 100059.0 122300.0 156646.0 166152.0 139433.0 150878.0 129538.0 137484.0 117330.0 True False 115453.56251585597 109992.19625310627 125216.09582533262 147869.63247318403 133595.70833211174 132120.88802223196 136585.74357787418 126137.76475685605 139494.44340582544 138601.00021623104 0.8329922752053533 0.793588762573919 0.903428515162108 1.0668727660153463 0.9638870435544437 0.9532462811675999 0.9854600137429538 0.9100783151641682 1.0064461525400288 1.0 17.08057814318026 -5.4952617053056585 5.016986562820339 0.9787525436136004 0.8185288604030284 0.7481597605449197 0.039520582331727554 0.0916721662712346 6.12927540267508 0.010643518087323965 0.02152512490981584 3.196968040226213e-06 5.4952617053056585 -0.160223683210572 VESGYFS(ph)LEK ddPTM_PC-9_Lapatinib_30min_R1 3 VESGYFSLEK 10 0 A0A494BZV2;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;A0A1W2PPU9;Q6WCQ1 A0A494BZV2;Q6WCQ1 MPRIP Myosin phosphatase Rho-interacting protein 1 VES(0.004)GY(0.002)FS(0.993)LEK;VES(0.003)GYFS(0.997)LEK;VESGYFS(1)LEK 116.01 0.0010762 35378900.0 101094.0 93950.0 105391.0 112626.0 97818.0 93500.0 84391.0 92422.0 85623.0 74471.0 True False 99652.38102163075 93732.46454727101 96726.15880102478 120908.89174932223 92064.53755758745 89501.22295914555 88760.35305166578 96716.26352309913 75979.23608983806 87343.21312362996 1.140928727691501 1.0731510920556286 1.1074261564446195 1.384296357155784 1.0540548517178396 1.0247072412193152 1.0162249575823359 1.107312864551961 0.8698928442475918 1.0 16.414407984542827 -6.503906733194207 24.68066659178052 1.014261837483785 1.1710209704175887 0.42469948006305513 0.09477974850709679 700.3782097044315 911122.5255551094 0.030055075236567877 0.03351505381671155 3.133958684587073e-07 6.503906733194207 0.1567591329338036 VESLESLYFT(ph)PIPAR ddPTM_PC-9_AZD4547_30min_R2 2 VESLESLYFTPIPAR 15 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 VESLES(0.085)LYFT(0.915)PIPAR;VESLESLYFT(1)PIPAR 145.49 7.673100000000001e-05 3359500.0 6122.8 7011.4 9131.3 7406.1 6732.3 9027.8 6909.7 8150.4 6785.0 9223.2 True False 8069.723037848449 9277.697934600066 9010.212995714566 5698.738068104368 5797.636352956927 8463.29023885849 7524.649914137433 6890.942957559796 7143.641248147965 8900.298575323593 0.9066800365801272 1.0424029998637154 1.0123495205762776 0.640286167916246 0.6513979619774878 0.9508995869333277 0.8454379199142603 0.7742372797093785 0.8026293935749497 1.0 13.119638019158362 -5.728944962629986 24.999738099463524 0.8006931775399463 0.9926702784627486 0.34815174446450836 0.11102495301195593 207.80966769587178 159877.89936761427 0.03071786230762619 0.053199777390843854 1.8666162288129052e-06 5.728944962629986 0.1919771009228023 VESLESLYFT(ph)PIPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VESLESLYFTPIPAR 15 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 VESLESLYFT(1)PIPAR;VESLESLYFT(1)PIPAR 170.74 5.7551000000000005e-21 2011500.0 13382.3 16497.1 17343.6 11969.5 16005.8 10395.099999999999 12534.1 10959.8 11104.5 9699.599999999999 True False 15647.659077526994 18134.823062464315 17757.137199969282 11298.887720642577 12869.578388596681 9849.962656472304 11346.779308974381 10672.11686286798 11266.882304849962 11458.06069800865 1.3656463768119569 1.5827131257574896 1.549750666188684 0.9861082096210455 1.1231899295867183 0.8596535588421323 0.9902879385991026 0.9314069059455007 0.9833149432353842 1.0 13.48407526499496 -5.76460293900094 24.996803380230887 0.980267554427196 1.507704432607397 0.8956429122497309 0.08091340727876231 22.120942078461358 174790.35966415354 0.02245813620352722 0.03495411331900752 1.7194797318585849e-06 5.76460293900094 0.5274368781802009 VESLESLYFT(ph)PIPAR ddPTM_PC-9_Lapatinib_30min_R1 2 VESLESLYFTPIPAR 15 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 VESLES(0.082)LY(0.001)FT(0.917)PIPAR;VESLESLYFT(1)PIPAR 162.64 0.00079214 1349700.0 5277.3 8786.6 11886.2 8861.099999999999 7933.1 6431.299999999999 7252.099999999999 7773.7 9010.1 4865.700000000001 True False 5202.044734261705 8766.255167547099 10908.962518058855 9512.774853763065 7466.4906550746955 6156.248291092541 7627.578253202176 8134.894481287086 7995.287657440762 5706.729761862285 0.9115631809003192 1.5361258607567907 1.9115961283049994 1.6669397800008579 1.3083659059822283 1.0787698993974377 1.3365935608475452 1.42549144970068 1.401027907589521 1.0 12.478448531494212 -6.37568571953712 6.584444347513724 1.271760062120889 1.5366647918211473 0.16985340063606857 0.2653870159141785 0.45780244312725554 23.447258318652345 0.0870997863874455 0.0987788275158297 4.210312005579245e-07 6.37568571953712 0.26490472970025825 VESSSESYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VESSSESYK 9 0 Q969N4 Q969N4 TAAR8 Trace amine-associated receptor 8 0 89.296 0.043566 22317000.0 87882.0 77862.0 103660.0 106360.0 113370.0 89299.0 110480.0 90860.0 77574.0 79707.0 False True 102758.68685138035 85591.62478796876 106131.64753273911 100400.99402377258 91155.96233335465 84616.00323809494 100014.53459406647 88475.02127412787 78708.37299441054 94157.24813973511 1.0913518489716285 0.9090285291786093 1.127174483426207 1.0663118985250224 0.9681247501846446 0.8986669099814772 1.0622074940597115 0.9396517317798576 0.8359247381317104 1.0 16.522784536022108 -6.364739874465087 5.174662390427638 0.9492270432913451 1.0437851849590565 0.2816794318249999 0.07669024029680054 0.3316108182158634 13.441334381805323 0.024256419035434667 0.027602030169654554 4.3177761742294235e-07 6.364739874465087 0.09455814166771137 VESSSESYK ddPTM_PC-9_Lapatinib_30min_R1 1 VESSSESYK 9 0 Q969N4 Q969N4 TAAR8 Trace amine-associated receptor 8 0 94.662 0.026148 24600000.0 107870.0 103050.0 92514.0 82711.0 85695.0 86835.0 88098.0 74418.0 88177.0 69106.0 False True 106331.75401906496 102811.39405637326 84907.8560343675 88793.8428558074 80654.58858285227 83121.26947227166 92659.28337317535 77875.73195626556 78245.5777150258 81050.88002204297 1.311913627466432 1.2684796763269222 1.0475870960472677 1.095532125396524 0.995110584375112 1.0255443179600963 1.1432236559057138 0.9608252487213725 0.9653883794197642 1.0 16.306540229654324 -5.228706724759073 2.504099098546577 1.0286938874616327 1.316629059980989 0.7937966433678904 0.05343868470640787 0.1351991326151285 1.603987689193514 0.015118868109052724 0.053378773010663794 5.905997723677914e-06 5.228706724759073 0.2879351725193562 VESTDVSDLLHQYR ddPTM_PC-9_AZD4547_30min_R2 2 VESTDVSDLLHQYR 14 0 P28062-2;Q5JNW7;A0A140T998;X5D2R7;P28062 P28062-2 PSMB8;PSM8 Proteasome subunit beta type-8;Proteasome subunit beta type 0 ; 198.37 6.6577e-08 3906900.0 23307.0 20225.8 35000.0 45763.0 48591.0 37156.0 29520.0 39665.0 29865.0 31135.0 False True 30718.14118428395 26763.394312923803 34535.877131406276 35213.04738130191 41844.97839171313 34832.62944626891 32147.22281218242 33535.68566102392 31443.602929394114 30044.97312675643 1.0224053473001125 0.8907777750378405 1.149472724961451 1.1720112789830746 1.3927447435274372 1.1593496622318111 1.0699700970460793 1.1161829141780408 1.0465512083081925 1.0 14.8748360110264 -5.274589531942853 23.876687112444966 1.1510395382087066 0.956591570317243 0.32072490230196493 0.10445747472169549 422.7286445964607 767548.3013040342 0.02882404106323714 0.060652048343211556 5.31386440286479e-06 5.274589531942853 -0.19444796789146368 VESTDVSDLLHQYR ddPTM_PC-9_Lapatinib_30min_R1 2 VESTDVSDLLHQYR 14 0 P28062-2;Q5JNW7;A0A140T998;X5D2R7;P28062 P28062-2 PSMB8;PSM8 Proteasome subunit beta type-8;Proteasome subunit beta type 0 ; 193.0 3.2211999999999992e-37 2651100.0 28174.0 29224.0 37766.0 30935.0 31063.0 32812.0 26699.0 31218.0 37578.0 27022.0 False True 27772.23359352119 29156.333623517192 34661.0252609758 33210.06309613482 29235.93541220773 31408.707248507857 28081.343580789693 32668.502246912052 33345.569926117234 31692.716695448267 0.8762970325453311 0.9199695281315107 1.0936590130171404 1.0478768171017816 0.9224812026419502 0.9910386525185075 0.8860503771462027 1.030788952579882 1.0521524628687433 1.0 14.951863712196777 -5.017299097315424 22.04715712030962 0.998800256528511 0.8872149248692052 0.3498194771519799 0.05830475333955981 161.0234275012589 205228.91305066858 0.015650463264459364 0.0439814197047866 9.60950246869024e-06 5.017299097315424 -0.11158533165930584 VET(ph)PSHPGGVSEEFWER ddPTM_PC-9_AZD4547_30min_R2 2 VETPSHPGGVSEEFWER 17 0 Q92620;H3BQT9 Q92620 DHX38 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 1 VET(0.91)PS(0.09)HPGGVSEEFWER;VET(0.886)PS(0.114)HPGGVSEEFWER 110.35 0.00083499 6658100.0 19628.3 15082.099999999999 24097.0 30786.0 30728.0 27554.0 22902.5 28874.0 25518.0 27214.0 True False 25869.691105997375 19957.093878459604 23777.458035299915 23688.763338958586 26461.947603888806 25831.044024181625 24940.778131978608 24412.186758512653 26866.829383970504 26261.24614329692 0.9850900054337487 0.7599446640712277 0.9054200210285533 0.9020426224139805 1.007642495694863 0.9836183661366312 0.9497179987532558 0.9295898079361998 1.0230599582886952 1.0 14.680647755875432 -6.044487653124208 2.9587628441385414 0.9769885630196933 0.8720309253239323 0.3823917226715857 0.05778047481574149 0.26140173467467986 4.5694295554964235 0.01701155311051614 0.02442253001494611 9.02635368787959e-07 6.044487653124208 -0.10495763769576094 VET(ph)PSHPGGVSEEFWER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VETPSHPGGVSEEFWER 17 0 Q92620;H3BQT9 Q92620 DHX38 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 1 VET(0.97)PS(0.03)HPGGVSEEFWER;VET(0.93)PS(0.07)HPGGVSEEFWER 96.096 0.0033253000000000002 6680100.0 19263.9 17478.1 20531.0 26581.0 25797.0 21236.0 23968.0 22979.0 22128.0 21972.2 True False 22524.897790631814 19213.210259261174 21020.536904251083 25091.752746764738 20742.26303531399 20122.346776158574 21697.57752670697 22375.82559826305 22451.580137936868 25955.5859281605 0.8678246699179092 0.7402341180984787 0.8098656282478625 0.9667187947986738 0.7991444728978235 0.7752607408614438 0.8359502107469742 0.8620813130628043 0.8649999348917813 1.0 14.663757435420598 -8.951326215382373 0.968934331025585 1.0002095591052798 0.8266606464406636 0.4376371336788697 0.057500021363698445 1.4475306158047303 2.186754488736645 0.05842207704690453 0.018780171554037415 1.1185973460964594e-09 8.951326215382373 -0.17354891266461614 VET(ph)PSHPGGVSEEFWER ddPTM_PC-9_Lapatinib_30min_R1 1 VETPSHPGGVSEEFWER 17 0 Q92620;H3BQT9 Q92620 DHX38 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 1 VET(0.745)PS(0.255)HPGGVSEEFWER 81.71300000000001 0.010320999999999999 3018400.0 15068.0 17437.0 16839.0 11999.0 15392.0 14667.0 12525.0 11698.0 14038.0 12856.0 True False 14853.127556867215 17396.62569782608 15454.562420419728 12881.446487490604 14486.672821836311 14039.726600446915 13173.483214704327 12241.53178564858 12456.892613306545 15078.142470456785 0.985076748410459 1.1537645125659206 1.024964610242971 0.8543125595695719 0.9607730428479925 0.9311310480024658 0.8736807760316408 0.811872669968062 0.826155651315395 1.0 13.880171088413087 -5.639888107127292 4.752521819362941 0.8899941227775084 1.0737584997530152 0.5490580747750986 0.06719478455387114 0.14571789439694927 5.383186002016747 0.01864869775152546 0.03313302802488635 2.2914579545035883e-06 5.639888107127292 0.18376437697550674 VETFSGVYK ddPTM_PC-9_Lapatinib_30min_R1 1 VETFSGVYK 9 0 P62081;A0A2R8Y623 P62081 RPS7 40S ribosomal protein S7 0 90.601 0.038922000000000005 8461500.0 76446.0 63723.0 66449.0 71971.0 62716.0 64267.0 54543.0 62814.0 65516.0 62978.0 False True 75355.86602152046 63575.453308629425 60985.81972055763 77263.98742821785 59027.168184400085 61518.45022369416 57366.96965905132 65732.56775378095 58136.898165934734 73863.66338708972 1.0202021205827647 0.8607135145119471 0.8256538726079088 1.046035139406888 0.7991367538198378 0.8328648675506485 0.7766602281613644 0.8899175147772327 0.7870838718256182 1.0 16.172577196646486 -6.326332565764645 24.999964962459963 0.8378216058176345 0.9245872057258567 0.19750844251877975 0.08637793785414292 331.09787739500166 127553.70185514935 0.02569767253981009 0.029138427075410735 4.717016921813846e-07 6.326332565764645 0.08676559990822219 VETGVLKPGMVVTFAPVNVTTEVK ddPTM_PC-9_AZD4547_30min_R2 1 VETGVLKPGMVVTFAPVNVTTEVK 24 1 Q5VTE0;P68104;A0A087WVQ9 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1 0 68.55199999999999 0.010119 0.0 13186.0 8269.0 13916.0 17853.0 15317.0 15823.0 11819.0 14243.0 15406.0 13845.0 False True 17378.873714161753 10941.79254089168 13731.46474744713 13737.266676100415 13190.498940665348 14833.585308653044 12870.868103563147 12042.07162157981 16220.329708027639 13360.290764090032 1.3007855907502344 0.8189786236016042 1.0277818791455307 1.02821614579105 0.9872913077699587 1.110274137784707 0.9633673645904203 0.9013330498724361 1.2140701122781592 1.0 13.705663785516059 VETGVLKPGMVVTFAPVNVTTEVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VETGVLKPGMVVTFAPVNVTTEVK 24 1 Q5VTE0;P68104;A0A087WVQ9 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1 0 ; 113.59 2.6316999999999994e-07 26038000.0 74983.0 79897.0 77052.0 92479.0 99446.0 85389.0 88469.0 89245.0 88297.0 73671.0 False True 87676.14091824304 87828.64613912233 78889.21190133716 87297.70145096336 79960.270179084 80911.05052125655 80088.5758599065 86902.4133128937 89588.17658348754 87026.96912068476 1.0074594324508537 1.0092118228008817 0.9064915473723718 1.003110901517243 0.9187987469516373 0.9297238699540719 0.920273067867543 0.9985687677159211 1.0294300432231647 1.0 16.409174932089414 -7.943639195816676 7.640801687800689 1.014531137204802 0.955951459580263 0.3025187066559386 0.03733222309562331 0.27598967448001094 31.868851935171612 0.02133685957393796 0.010151710667113137 1.1385727991786963e-08 7.943639195816676 -0.058579677624539084 VETGVLKPGMVVTFAPVNVTTEVK ddPTM_PC-9_Lapatinib_30min_R1 6 VETGVLKPGMVVTFAPVNVTTEVK 24 1 Q5VTE0;P68104;A0A087WVQ9 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1 0 ;;;;; 135.23 2.2941999999999997e-07 37864200.0 152505.3 131744.2 154757.0 131061.9 151052.3 125836.5 146350.0 132022.0 133246.6 139682.5 False True 150330.54645595315 131439.15439923946 142033.47683929544 140700.6293356817 142167.70069424796 120454.7662342086 153927.2869039505 138156.2240900066 118238.96475909771 163826.4340097678 0.9176208184265917 0.8023073638494913 0.866975330921425 0.8588396017170997 0.86779463615604 0.7352584273855752 0.9395753977943078 0.8433084985648246 0.7217331285624392 1.0 17.32180863445558 VETTEDLVAK ddPTM_PC-9_Lapatinib_30min_R1 1 VETTEDLVAK 10 0 P38117-2;P38117 P38117-2 ETFB Electron transfer flavoprotein subunit beta 0 134.25 6.9986e-05 0.0 19389.0 21015.0 17082.0 20504.0 17305.0 13023.0 15656.0 17270.0 21543.0 13644.0 False True 19112.509304492865 20966.341058657756 15677.583898426865 22011.932559338897 16287.153922939013 12466.036648095745 16466.591074603668 18072.42724723464 19116.60048215294 16002.347220512787 1.1943566178837366 1.310204107543787 0.9797052696325936 1.3755439908917022 1.0177978079403966 0.7790130082989336 1.029010984931997 1.1293610242420122 1.1946122789816804 1.0 13.965995914351398 -6.317403164511959 23.77172936798725 1.019338284964904 1.2049528656769526 0.30935741462001387 0.1385929447625284 227.7926639458194 96758.58760092026 0.04458998946286971 0.05056033330476389 4.815006031607818e-07 6.317403164511959 0.18561458071204862 VEVGKDQEFTVDTR ddPTM_PC-9_AZD4547_30min_R2 1 VEVGKDQEFTVDTR 14 1 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 84.89200000000001 0.0092144 5753000.0 34575.0 40245.0 37259.0 57749.0 59468.0 52945.0 33801.0 56685.0 38403.0 44312.0 False True 45569.130795324025 53253.40921613083 36764.92131540189 44435.86026315597 51211.89469239974 49634.34078029678 36809.22351878653 47925.63574171537 40432.90417872163 42760.650367523085 1.0656790858806486 1.2453835186888795 0.8597839602394125 1.03917643630849 1.197640687226203 1.1607480324479418 0.8608200109777401 1.1207882791725525 0.9455633586300785 1.0 15.383996175425086 -7.235905744524119 24.993927877991016 0.991858546541783 1.0930554377365298 0.18524161600530953 0.11523702543647234 1519.5439141861407 1487427.4529737434 0.04482867748696772 0.034711340572471105 5.808904752296861e-08 7.235905744524119 0.10119689119474684 VEVGKDQEFTVDTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VEVGKDQEFTVDTR 14 1 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 90.79299999999999 0.0062119 4757600.0 27251.0 28251.0 24917.0 33931.0 43078.0 35730.0 32986.0 35549.0 34668.0 26507.0 False True 31864.056068216087 31055.572575645387 25511.11577824873 32029.95607578623 34637.175138010454 33856.25590092982 29861.327282040907 34615.87641727894 35174.953914587604 31312.509270703456 1.0176142637673777 0.9917944393137964 0.8147260111829296 1.0229124660333124 1.106176922410291 1.0812373932805934 0.953654880350956 1.1054967239456013 1.1233514890324654 1.0 14.934451504996487 -5.987626136669377 24.99734442633451 1.0626923117918732 0.9418197320326726 0.37621820536921935 0.069254002478381 241.59216861518388 488053.5300175976 0.01986132862955825 0.029438559059794842 1.028901649171846e-06 5.987626136669377 -0.12087257975920063 VEVKEEEESSSNGTASQS(ph)TSPSQPR ddPTM_PC-9_AZD4547_30min_R2 1 VEVKEEEESSSNGTASQSTSPSQPR 25 1 Q92793;Q92793-2;I3L466 Q92793 CREBBP CREB-binding protein 1 VEVKEEEESSSNGT(0.001)AS(0.037)QS(0.303)T(0.303)S(0.303)PS(0.054)QPR 118.16 2.9756e-09 6679600.0 16191.0 14109.0 17080.0 23957.0 16176.0 20887.0 15735.0 16831.0 15683.0 18673.0 True False 21339.401206278864 18669.458333467264 16853.508040126246 18434.083781960333 13930.24161808465 19580.932588120846 17135.38451726594 14230.155687903523 16511.97136252094 18019.263953618865 1.184254876403717 1.0360832929425965 0.9353050204218526 1.02302090859034 0.7730749521146226 1.086666616268105 0.9509480831942964 0.789719032060998 0.9163510454712436 1.0 14.13725246105875 VEVKEEEESSSNGTASQS(ph)TSPSQPR ddPTM_PC-9_Lapatinib_30min_R1 1 VEVKEEEESSSNGTASQSTSPSQPR 25 1 Q92793;Q92793-2;I3L466 Q92793 CREBBP CREB-binding protein 1 VEVKEEEESSS(0.001)NGT(0.188)AS(0.049)QS(0.442)T(0.088)S(0.214)PS(0.017)QPR 79.873 4.0311e-05 7052600.0 9740.2 9673.3 7783.6 9429.0 10214.0 10182.0 7272.4 9677.9 9766.6 10075.0 True False 9601.302961866078 9650.90206817578 7143.662453564885 10122.44011422193 9613.232601496626 9746.539595401275 7648.929287873513 10127.570564910957 8666.5826611426 11816.450325906359 0.8125369884402767 0.8167344508711862 0.6045523195661506 0.856639670547213 0.8135465674002451 0.8248280428203539 0.6473119318332019 0.8570738492174164 0.7334336811912122 1.0 13.528509093040686 -10.953384960630032 3.222870446074754 1.0032893726489482 0.7741370391969243 0.4046175352663479 0.08221759646526226 117092573.67830446 156289361.7604557 3542842.7358727036 0.02022746616071311 1.1133072554109793e-11 10.953384960630032 -0.2291523334520239 VEVKEEEESSSNGTASQSTS(ph)PSQPR ddPTM_PC-9_AZD4547_30min_R2 1 VEVKEEEESSSNGTASQSTSPSQPR 25 1 Q92793;Q92793-2;I3L466 Q92793 CREBBP CREB-binding protein 1 VEVKEEEESSSNGT(0.002)AS(0.011)QS(0.046)T(0.203)S(0.604)PS(0.133)QPR 86.869 4.2214e-06 6995800.0 28451.0 24677.0 28153.0 42096.0 29883.0 29992.0 33947.0 29384.0 21961.0 30175.0 True False 37497.82618243715 32653.357664963616 27779.672825156584 32391.417576716718 25734.261268127066 28116.595498775354 36968.21723594704 24843.377977146763 23121.813625729912 29118.582434555174 1.2877627634076818 1.1213924214323603 0.9540187228410646 1.112396788185597 0.8837745218526876 0.9655894328636425 1.2695747575979752 0.853179512875771 0.7940569798580283 1.0 14.829652502791511 -1.5228788267701951 0.7383666252690184 0.9724828249770423 53.7111645360459 0.36669485601299934 0.1277702865148993 409.1811089090325 1.8552400562865066 0.04999418136571121 35837.59077246217 0.02999999437088059 1.5228788267701951 52.73868171106886 VEVKEEEESSSNGTASQSTS(ph)PSQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VEVKEEEESSSNGTASQSTSPSQPR 25 1 Q92793;Q92793-2;I3L466 Q92793 CREBBP CREB-binding protein 1 VEVKEEEESSSNGT(0.001)AS(0.01)QS(0.016)T(0.071)S(0.714)PS(0.187)QPR 88.045 3.7472000000000003e-06 6337100.0 5465.1 6931.3 6053.6 7799.8 5510.9 8260.5 7415.0 6424.2 6856.7 2171.1 True False 6390.233489354803 7619.393656634133 6197.940782405844 7362.80249329279 4431.0787053266595 7827.304838220846 6712.597520048907 6255.57155700254 6956.966265898034 2564.703243581855 2.4916073644568044 2.97086755580849 2.416630773137645 2.8708204396427273 1.7277159517052862 3.0519339256144353 2.617299891068145 2.4391015111229915 2.712581380831398 1.0 11.324576188942444 -11.035157798591854 3.054322917536088 0.9487057020781028 2.5879425437545223 0.6433885431158449 0.35483909332907826 61197474.29276972 76157297.58076838 26528242.443529308 0.08591661026465165 9.222362766211684e-12 11.035157798591854 1.6392368416764196 VEVKEEEESSSNGTASQSTS(ph)PSQPR ddPTM_PC-9_Lapatinib_30min_R1 1 VEVKEEEESSSNGTASQSTSPSQPR 25 1 Q92793;Q92793-2;I3L466 Q92793 CREBBP CREB-binding protein 1 VEVKEEEESSSNGT(0.001)AS(0.003)QS(0.017)T(0.111)S(0.757)PS(0.111)QPR 95.835 1.1993e-06 6865200.0 18061.0 14403.0 18527.0 16796.0 19483.0 18543.0 18344.0 16793.0 20018.0 16632.0 True False 17803.446828018237 14369.650738417682 17003.781576288166 18031.233869813495 18337.048245051774 17749.959115844238 19293.762562118653 17573.26408586053 17763.362041114866 19506.819039253052 0.9126781148783323 0.736647564603025 0.8716839758482359 0.9243554181504285 0.9400327243592418 0.9099361141417506 0.9890778462287638 0.9008779981245696 0.9106232033716068 1.0 14.251690917596363 -5.630287411140681 3.4776599294167694 0.9363620902643468 0.8205981771845933 0.4597710693508684 0.050426560715377905 0.18595450147721918 4.353795618719381 0.013237126888127348 0.024751428302414426 2.342677944626064e-06 5.630287411140681 -0.11576391307975353 VEVKVPPAPVPCPPPSPGPSAVPSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 VEVKVPPAPVPCPPPSPGPSAVPSSPK 27 1 O95817 O95817 BAG3 BAG family molecular chaperone regulator 3 1 VEVKVPPAPVPCPPPS(0.011)PGPS(0.043)AVPS(0.349)S(0.596)PK 84.47 4.523e-07 3154200.0 76558.0 3403.8 7356.5 6652.6 4421.3 5061.9 759.33 729.97 7058.2 1065.3 True False 75466.26888098243 3395.9187102288497 6751.676966911201 7141.854396423036 4161.247826610247 4845.4143368652285 798.6443919697754 763.887071086501 6263.231189858979 1249.4356855769763 60.40028290542454 2.717961996307677 5.403781118828335 5.716064043044362 3.3305018214592024 3.8780822356835976 0.6392040832425638 0.6113856678695277 5.012848009833083 1.0 10.287060925592758 -4.761125303412901 24.99999985403874 3.2346371050403087 60.40034668480639 0.9888300012977308 1.825547889392894 0.7263070478168453 57723.60498789131 0.48379880513620727 2.744516364384246 1.7333038297129057e-05 4.761125303412901 57.16570957976608 VEVNTNS(ph)GEIIHK ddPTM_PC-9_Lapatinib_30min_R1 1 VEVNTNSGEIIHK 13 0 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 VEVNT(0.117)NS(0.883)GEIIHK 80.545 0.0071608999999999996 3315300.0 40509.0 26954.0 28003.0 25871.0 27674.0 30761.0 22743.0 24852.0 28347.0 20111.0 True False 39931.334231559194 26891.58966904883 25700.70143470596 27773.639643126055 26046.269729177366 29445.42373739333 23920.521257646356 26006.714646686476 25154.26235285659 23587.159553776943 1.6929267867340605 1.1400944487503057 1.0896056125838425 1.177489793962018 1.1042563081745318 1.2483666662049742 1.0141331856050482 1.1025793329371911 1.0664388094508273 1.0 14.525714074328121 -4.761323593157232 5.341622446956631 1.1093956884946552 1.7240070228028714 0.8683744558430697 0.06877795042780271 0.0512104839946908 4.364407808125715 0.016590184247832755 0.1171390734106769 1.732512620205935e-05 4.761323593157232 0.6146113343082162 VEVS(ph)EDEPASK ddPTM_PC-9_AZD4547_30min_R2 2 VEVSEDEPASK 11 0 O75683 O75683 SURF6 Surfeit locus protein 6 1 VEVS(1)EDEPASK;VEVS(1)EDEPASK 154.28 0.00030471 13262700.0 65201.0 72033.0 94094.0 77319.0 82258.0 87882.0 77695.0 104760.0 90036.0 74818.0 True False 85933.56173495077 95316.25856791044 92846.25208007266 59494.29911664197 70837.89657643475 82386.7246473518 84609.70448484128 88571.7491453135 94795.11914786299 72198.64459282669 1.1902378807744087 1.320194570209156 1.285983311787787 0.824036232981485 0.9811527207461297 1.1411117911143909 1.1719015635543897 1.2267785585840978 1.3129764371959052 1.0 16.13968413276214 VEVS(ph)EDEPASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VEVSEDEPASK 11 0 O75683 O75683 SURF6 Surfeit locus protein 6 1 VEVS(1)EDEPASK;VEVS(1)EDEPASK 156.0 0.00041297 7270000.0 42347.0 50655.0 63085.0 50494.0 73267.0 46532.0 62405.0 43858.0 51171.0 44778.0 True False 49515.5107086252 55683.69363276756 64589.18565119476 47664.98488375676 58910.85730156026 44091.780005095614 56493.54662692546 42706.77397139215 51919.27906897898 52895.89693754702 0.9360936022521187 1.0527034582382075 1.22106230143812 0.901109304187312 1.1137131745986832 0.8335576586810461 1.0680137760708757 0.8073740392721777 0.9815369825428784 1.0 15.690868198345651 -6.750627242080956 24.999932591591254 0.9341771876574252 1.0471622455001646 0.19278789212885306 0.10911455575865037 343.1894964696987 793525.3125807876 0.03471549963200231 0.034383601005284245 1.7757129335366013e-07 6.750627242080956 0.11298505784273938 VEVS(ph)EDEPASK ddPTM_PC-9_Lapatinib_30min_R1 2 VEVSEDEPASK 11 0 O75683 O75683 SURF6 Surfeit locus protein 6 1 VEVS(1)EDEPASK;VEVS(1)EDEPASK 187.62 0.00084791 14745600.0 69568.0 90248.0 87832.0 78539.0 88318.0 77632.0 89159.0 87447.0 89415.0 81762.0 True False 68575.94756279125 90039.03630082057 80610.79200132466 84315.02005842351 83123.30887986872 74311.86032903081 93775.21676166258 91510.10686096862 79344.14111830786 95894.45275898317 0.7151190250300189 0.9389389449577512 0.840619969998976 0.8792481486946603 0.8668208273609646 0.7749338798126615 0.977900327533575 0.9542794627648173 0.8274111675440484 1.0 16.549159741105925 -14.522878744662632 0.019715454153706864 2.121328108123192 3.93155535423827e-09 0.30942487874902436 0.07226899049224608 4367.537124762354 6.495536437670634 469.43603116880496 258.4985870624704 3.000000004266956e-15 14.522878744662632 -2.1213281041916363 VEVTEFEDIK ddPTM_PC-9_AZD4547_30min_R2 4 VEVTEFEDIK 10 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;A0A087X027;P0DME0;Q01105-2 Q01105;Q01105-2 SET;SETSIP Protein SET;Protein SETSIP 0 ;;; 147.95 0.00067085 14371200.0 77841.0 62689.0 71611.0 84315.0 83998.0 85917.0 68142.0 74963.0 71120.0 71847.0 False True 102592.8188066181 82951.99329978957 70661.39135020379 64877.47940376447 72336.32761102084 80544.59640798502 74206.5059914544 63379.19082837094 74879.25800564227 69331.6583985247 1.479739864534975 1.1964518838273555 1.01917930397735 0.9357554817287479 1.0433376221180954 1.1617289744463826 1.0703120003982687 0.9141450282937351 1.0800153888607347 1.0 16.08122664944745 -4.842952906087289 2.2625332120834494 1.028739145787748 1.5591370544783434 0.8084900878965346 0.06763587780945518 0.23124849394934022 1.5764122260763627 0.019256401949346923 0.2366742127368054 1.4356451030256633e-05 4.842952906087289 0.5303979086905954 VEVTEFEDIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VEVTEFEDIK 10 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;A0A087X027;P0DME0;Q01105-2 Q01105;Q01105-2 SET;SETSIP Protein SET;Protein SETSIP 0 ;; 150.85 0.00067085 10326500.0 50487.0 48395.0 48313.0 59771.0 57114.0 46778.0 54475.0 50202.0 47621.0 39736.0 False True 59033.45193629685 53199.33576858727 49464.96514807284 56422.224650196586 45922.9216962795 44324.87933203736 49314.733635153636 48884.25069341577 48317.36703491919 46939.82224999704 1.2576411478912357 1.1333518794607413 1.053795322969634 1.20201189407359 0.9783360800068304 0.9442915888340448 1.0505948099357523 1.041423856125038 1.0293470388018402 1.0 15.518524758276035 -1.52287874528034 0.4489055860002683 1.0105565689645417 6.461265275678416 0.6091962077078346 0.05892768537658831 63.13200082827597 0.7623557525423883 0.03876023875846004 315.1897269528552 0.02999999999999983 1.52287874528034 5.450708706713875 VEVTEFEDIK ddPTM_PC-9_Lapatinib_30min_R1 4 VEVTEFEDIK 10 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;A0A087X027;P0DME0;Q01105-2 Q01105;Q01105-2 SET;SETSIP Protein SET;Protein SETSIP 0 ;;; 176.83 0.00061871 47171900.0 190015.0 153818.0 175652.0 152832.0 172933.0 134802.0 170014.0 152242.0 139957.0 152795.0 False True 187305.35125551623 153461.84387154944 161210.57059632798 164071.77511260644 162761.42093935938 129036.83269881015 178816.49303510913 159315.7191067455 124193.56884745287 179205.41216346022 1.0451991878720033 0.8563460334086949 0.8995853900287428 0.9155514508844755 0.9082394274504297 0.7200498642368605 0.9978297579093407 0.8890117613268702 0.6930235384530189 1.0 17.4512546831687 -4.757829381312714 24.957901675196073 0.8740368475149769 1.0451994352103962 0.22009817417499267 0.09578749121640642 155.1763933941342 1072654.8777933484 0.022870944441405347 0.16386460872150674 1.746508158419601e-05 4.757829381312714 0.17116258769541925 VEYISS(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 2 VEYISSPLK 9 0 Q15697 Q15697 ZNF174 Zinc finger protein 174 1 VEYIS(0.114)S(0.886)PLK;VEYIS(0.113)S(0.887)PLK 130.41 0.0012667 13377500.0 100878.0 95298.0 123444.0 133354.0 128423.0 115810.0 123531.0 125218.0 106677.0 128331.0 True False 132955.10560725094 126101.21484603897 121807.05190312318 102611.29559876183 110593.6831923397 108568.38239241015 134525.01968874354 105868.43532338545 112315.72843458824 123838.17075091621 1.073619747457932 1.0182742048061626 0.9835986042471643 0.8285918225096415 0.893050038786377 0.8766956240881563 1.0862968895052763 0.8548934038788859 0.9069556482750072 1.0 16.918096540727568 -5.355780298331357 2.7795302781223383 0.9186076339165182 1.0525955904723237 0.3223981684057886 0.0719295574440767 0.3175018082335848 4.686118005874918 0.019894224068658845 0.05308111671799948 4.407777885703404e-06 5.355780298331357 0.13398795655580542 VEYISS(ph)PLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VEYISSPLK 9 0 Q15697 Q15697 ZNF174 Zinc finger protein 174 1 VEYIS(0.041)S(0.959)PLK 137.46 0.00094373 8210700.0 73334.0 71393.0 67146.0 85794.0 86432.0 66416.0 85317.0 87238.0 70856.0 59866.0 True False 85747.99778747764 78480.42522010025 68747.01529262292 80987.24032790105 69496.27005730366 62933.02804131421 77235.15611841045 84948.09493630147 71892.13495361782 70719.2319010047 1.212513137975123 1.109746572614928 0.972112018819116 1.1451940038216175 0.9827067996805594 0.8898997677097242 1.092137938185287 1.20120217164144 1.0165853477347573 1.0 16.109814984897724 -4.900131401588832 3.461828990303135 1.0428955008168388 1.2150846068373327 0.28555139320326883 0.08537973656395705 0.3645424556962124 7.6492947441038766 0.02291333551120122 0.13808287709227057 1.2585445647352998e-05 4.900131401588832 0.17218910602049387 VEYISS(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 1 VEYISSPLK 9 0 Q15697 Q15697 ZNF174 Zinc finger protein 174 1 VEYIS(0.267)S(0.733)PLK 108.43 0.0025416 0.0 92543.0 93116.0 104780.0 96965.0 85637.0 90906.0 63157.0 86309.0 85771.0 75580.0 True False 91223.31984969236 92900.39562302986 96165.39286249656 104096.1295657577 80600.0000288199 87018.16229223626 66426.96043042553 90319.23122649555 76110.56677132902 88643.90229598017 1.0290986462340024 1.0480178920016106 1.084850625612152 1.174317994464897 0.9092560000314308 0.9816598777621997 0.7493686391267758 1.0188995394733582 0.8586102912888176 1.0 16.435733772885314 -6.281841252287001 24.65493816070483 0.9151655373034275 1.0815517116783104 0.49676925158752283 0.08098979529336468 554.8913391180034 670564.8121842712 0.02436569802855165 0.02766515018507322 5.225871754429874e-07 6.281841252287001 0.1663861743748829 VFAEYPGS(ph)S(ph)AQLR ddPTM_PC-9_AZD4547_30min_R2 1 VFAEYPGSSAQLR 13 0 Q5T3Q7;Q9H583 Q5T3Q7 HEATR1 HEAT repeat-containing protein 1;HEAT repeat-containing protein 1, N-terminally processed 2 VFAEYPGS(1)S(1)AQLR 85.163 0.018352 9180700.0 0.0 0.0 2749.8 4201.9 1410.0 2412.7 1787.1 4049.9 0.0 0.0 True False 0.0 0.0 2713.3358553125977 3233.216873707856 1214.2458383716214 2261.8334875932005 1946.1484379285657 3424.0810124437335 0.0 0.0 0.0 VFDDES(ph)DEKEDEEYADEK ddPTM_PC-9_Lapatinib_30min_R1 4 VFDDESDEKEDEEYADEK 18 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 VFDDES(0.977)DEKEDEEY(0.023)ADEK;VFDDES(0.623)DEKEDEEY(0.377)ADEK;VFDDES(0.914)DEKEDEEY(0.086)ADEK;VFDDES(0.657)DEKEDEEY(0.343)ADEK 65.298 0.007119199999999999 77927000.0 48134.6 117726.0 56400.0 72973.0 85703.0 67818.0 118074.0 101630.0 66356.4 90362.0 True False 47448.19177719542 117453.41268006361 51763.00971029594 78339.67785079178 80662.11803858091 64917.582231479406 124187.29397948085 106352.10081855554 58882.64346813046 105980.95130020357 0.4477049054107168 1.1082502208096146 0.4884180513125524 0.7391863999114839 0.761100151008231 0.6125400973953582 1.1717888210656429 1.0035020398835697 0.5555964797988878 1.0 16.69344545682621 -7.235240399963399 24.993678182960657 0.9330137529252509 0.7076615574105413 0.2154756001815289 0.22314282307973657 1235.9687016903022 1179108.843971316 0.08236565427199266 0.06377895155983572 5.817810887211178e-08 7.235240399963399 -0.22535219551470964 VFDDES(ph)DEKEDEEYADEKGLEAADK ddPTM_PC-9_AZD4547_30min_R2 1 VFDDESDEKEDEEYADEKGLEAADK 25 2 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 VFDDES(0.92)DEKEDEEY(0.08)ADEKGLEAADK 44.863 0.015759 12583000.0 14859.0 18375.0 10614.0 9941.8 11758.0 13509.0 11337.0 11262.0 13503.0 11833.0 True False 19583.8529136 24314.359407290463 10473.251424935594 7649.871609278842 10125.604657853564 12664.280094457063 12345.971037320884 9521.716675014524 14216.741013079136 11418.730271684892 1.71506397363306 2.1293400254477466 0.9171993011259922 0.6699406525301927 0.8867539925136948 1.109079538016654 1.0812034914192936 0.8338682540409589 1.245036941483108 1.0 13.479114615838057 -5.26751969660005 24.955540950883492 0.957503273305891 1.9222020245833016 0.8230096966150415 0.1769686075665915 159.91206346488795 656331.8824631734 0.04659448566298852 0.1011402029025403 5.401076186555776e-06 5.26751969660005 0.9646987512774106 VFDDES(ph)DEKEDEEYADEKGLEAADK ddPTM_PC-9_Lapatinib_30min_R1 1 VFDDESDEKEDEEYADEKGLEAADK 25 2 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 VFDDES(0.527)DEKEDEEY(0.473)ADEKGLEAADK 60.747 0.000956 17491000.0 13551.0 23844.0 14458.0 21419.0 21843.0 17708.0 20229.0 24414.0 16536.0 21012.0 True False 13357.760255050947 23788.790682970986 13269.31904949394 22994.224711689418 20558.237684990287 16950.67011936415 21276.358638742833 25548.363567688866 14673.541548200392 24643.896203269902 0.5420311847149624 0.965301528896009 0.5384424175481346 0.9330596315625775 0.8342121519836013 0.687824278253332 0.8633520634582026 1.0367014759743614 0.5954229569532685 1.0 14.588942743892707 -4.889669406169606 0.0432354530219299 1.4656054147054354 2.1824987785744136e-10 0.15351599803995386 0.1685555546573437 615.2783737532286 4.33341643859628 53.512557460201904 97.85859329161558 1.2892305669023192e-05 4.889669406169606 -1.4656054144871855 VFDGIPPPYDK ddPTM_PC-9_Lapatinib_30min_R1 1 VFDGIPPPYDK 11 0 P40429;M0QYS1;Q8J015;Q6NVV1 P40429 RPL13A;RPL13a;RPL13AP3 60S ribosomal protein L13a;Putative 60S ribosomal protein L13a protein RPL13AP3 0 138.66 0.00047693 2094200.0 80864.0 83834.0 76390.0 83872.0 81831.0 76808.0 95950.0 80345.0 75674.0 82871.0 False True 79710.86453135851 83639.88752374548 70109.50907392747 90040.22666879024 77017.86146593597 73523.10088819302 100917.82151304427 84078.12201384312 67150.79723745256 97195.14193133364 0.8201116120358423 0.8605356796827904 0.7213272976488722 0.9263860814401794 0.7924044343733507 0.7564483103500746 1.0383010869446605 0.8650444903228042 0.6908863540205868 1.0 16.568596585492365 VFDGIPPPYDKK ddPTM_PC-9_Lapatinib_30min_R1 1 VFDGIPPPYDKK 12 1 P40429;M0QYS1;Q8J015;Q6NVV1 P40429 RPL13A;RPL13a;RPL13AP3 60S ribosomal protein L13a;Putative 60S ribosomal protein L13a protein RPL13AP3 0 69.86399999999999 0.019701 13936000.0 33959.0 32574.0 26812.0 23455.0 26891.0 25370.0 19800.0 20234.0 23157.0 20700.0 False True 33474.73843268209 32498.576904340578 24607.620857313024 25179.958943586298 25309.324249740137 24284.98424035853 20825.147117855933 21174.145507848618 20548.81480597947 24277.967418983768 1.37881140768428 1.3386036954201048 1.0135782964298523 1.0371526787657368 1.0424811852226936 1.0002890201330972 0.8577796797590248 0.8721547871957285 0.846397659711482 1.0 14.567360022012043 -4.349724898207294 0.51747844347157 0.893696753493749 2.0488456977202842 0.8465192246624813 0.06860815846743779 2.385066778295092 0.35182560583216177 0.04124692130741236 1.8334451729847232 4.4696663140264117e-05 4.349724898207294 1.1551489442265352 VFDKDGNGY(ph)ISAAELR ddPTM_PC-9_AZD4547_30min_R2 1 VFDKDGNGYISAAELR 16 1 P0DP25;P0DP24;P0DP23;E7EMB3;G3V361;A0A590UJI2;Q96HY3 P0DP25 CALM2;CALM1 1 VFDKDGNGY(0.554)IS(0.446)AAELR 82.94200000000001 0.027701 9188200.0 11738.0 12177.0 22216.0 31397.0 30236.0 24186.0 29528.0 39638.0 39218.0 27088.0 True False 15470.439834432793 16112.977115786447 21921.401324323473 24158.906728814472 26038.25331135062 22673.645596605103 32155.9347966844 33512.85789062563 41290.983414866154 26139.657364945513 0.5918378966657523 0.6164188340660767 0.8386261923127226 0.9242243075922135 0.9961206816072931 0.8674040856790842 1.2301590012349202 1.282069516931309 1.5796298642475424 1.0 14.673952610157407 -6.341014502203681 0.5782668033506161 1.3184585729169367 0.5629075124839109 0.6835801771188136 0.16216333975482686 0.5807919495981063 0.40775813067246597 0.12441204949385068 0.22917744627864364 4.5602168796637725e-07 6.341014502203681 -0.7555510604330258 VFDKDGNGY(ph)ISAAELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VFDKDGNGYISAAELR 16 1 P0DP25;P0DP24;P0DP23;E7EMB3;G3V361;A0A590UJI2;Q96HY3 P0DP25 CALM2;CALM1 1 VFDKDGNGY(0.876)IS(0.124)AAELR;VFDKDGNGY(0.812)IS(0.188)AAELR;VFDKDGNGY(0.993)IS(0.007)AAELR 104.55 0.005743600000000001 16757300.0 30638.9 23536.4 39222.5 48169.0 66557.0 45550.0 50520.0 56957.0 44458.0 40180.8 True False 35825.46062414096 25872.938245351314 40157.7131521596 45470.247096005034 53515.633633422265 43161.277813807785 45734.37986687404 55461.93910092987 45108.11414372728 47465.260968962204 0.754772224839708 0.5450920887650818 0.8460442928654486 0.9579689686260923 1.1274694911804326 0.909323512242589 0.9635337283151146 1.168474331937135 0.9503395372296326 1.0 15.534584394813434 -5.5762684570962 2.641892675694987 1.0190123878195643 0.6507834573706638 0.7172622919516124 0.09036718788561499 0.13334054505699472 1.8681042864198225 0.0249951790166648 0.05312911629387521 2.652965137066011e-06 5.5762684570962 -0.3682289304489005 VFDKDGNGY(ph)ISAAELR ddPTM_PC-9_Lapatinib_30min_R1 1 VFDKDGNGYISAAELR 16 1 P0DP25;P0DP24;P0DP23;E7EMB3;G3V361;A0A590UJI2;Q96HY3 P0DP25 CALM2;CALM1 1 VFDKDGNGY(0.699)IS(0.301)AAELR 78.508 0.0453 10022000.0 23094.0 23155.0 23410.0 21886.0 30146.0 23519.0 29363.0 21741.0 24859.0 28248.0 True False 22764.675325079093 23101.38602013895 21485.320165213263 23495.569449555744 28372.871549316347 22513.147195466787 30883.27246573757 22751.1662294226 22059.117643124922 33130.62916190598 0.6871187146440977 0.697281838725273 0.6485032342795759 0.709179693954356 0.8563939854767334 0.6795267027815063 0.9321667969181687 0.6867109621806453 0.6658224791121317 1.0 15.015877980497594 -6.056738874077018 7.505199636385932 0.7878274740760005 0.6793840111651931 0.23088182761692255 0.10427387714238091 0.4583403619075095 54.13349092215661 0.029614664575149153 0.03861662037706045 8.775282893002102e-07 6.056738874077018 -0.10844346291080742 VFDKDGNGYISAAELR ddPTM_PC-9_AZD4547_30min_R2 2 VFDKDGNGYISAAELR 16 1 P0DP25;P0DP24;P0DP23;E7EMB3;G3V361;A0A590UJI2;Q96HY3 P0DP25 CALM2;CALM1 0 ; 103.3 0.0017934000000000001 75129000.0 195033.0 158612.0 235120.0 347580.0 291980.0 236750.0 244340.0 327810.0 247790.0 277940.0 False True 257049.43706158924 209880.22717328733 232002.15517532098 267450.80105746834 251443.61694166364 221945.98507385532 266085.78665069956 277154.4968244106 260887.6735266888 268209.40519835165 0.9583908396929288 0.7825237411718372 0.865003801800858 0.9971715975421432 0.937489931629023 0.827510075232885 0.9920822368399737 1.0333511482173554 0.9727014357820594 1.0 18.03300030301071 -7.385971903375602 7.185127306537676 1.004112021297619 0.8950165800598272 0.4215158027356114 0.06021221708833526 0.2691501885553079 14.591564482224822 0.02660239770478613 0.017834140749816506 4.111763212421004e-08 7.385971903375602 -0.10909544123779169 VFDKDGNGYISAAELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VFDKDGNGYISAAELR 16 1 P0DP25;P0DP24;P0DP23;E7EMB3;G3V361;A0A590UJI2;Q96HY3 P0DP25 CALM2;CALM1 0 91.307 0.0042778 31058000.0 94630.0 59019.0 102280.0 119370.0 132460.0 81526.0 114240.0 133200.0 103060.0 80632.0 False True 110648.98997230538 64878.01627701723 104718.74309906029 112682.08590276181 106505.41387206606 77250.63304167929 103418.3601740237 129703.64113706621 104567.0575296353 95249.94331743913 1.1616698773619833 0.6811344344930318 1.0994100306187535 1.1830147292290416 1.1181677401855858 0.8110307507924325 1.0857577083207464 1.3617188275357117 1.0978175302545332 1.0 16.53943061361815 -7.52623224869704 24.997587542453385 1.1826085782528561 1.0059082480179284 0.11908410584247286 0.1711853769283566 184.03792417797354 1371806.6664064408 0.08002620719093392 0.04649203560620686 2.9769240269109022e-08 7.52623224869704 -0.1767003302349277 VFDKDGNGYISAAELR ddPTM_PC-9_Lapatinib_30min_R1 2 VFDKDGNGYISAAELR 16 1 P0DP25;P0DP24;P0DP23;E7EMB3;G3V361;A0A590UJI2;Q96HY3 P0DP25 CALM2;CALM1 0 ; 82.48299999999999 0.0082021 83588000.0 229626.0 229806.0 298489.0 261861.0 276848.0 275017.0 241586.0 216190.0 267819.0 257660.0 False True 226351.49113174845 229273.8983262388 273948.3866208608 281119.13148268854 260564.34494410985 263255.16400593927 254094.14099062324 226234.97664039678 237654.40396090245 302196.1876896315 0.7490216632521559 0.7586922259976124 0.9065249588860386 0.9302537322919838 0.8622357116288994 0.8711399240956463 0.8408251041591196 0.7486361041481763 0.7864242291665962 1.0 18.20512593495294 -5.239814420458243 20.914387537591484 0.8604003274003444 0.7538565564551128 0.3123694764520003 0.0670875635318932 135.4813148617264 131023.30713224824 0.01789327918982274 0.04713607462590928 5.756858826666875e-06 5.239814420458243 -0.1065437709452316 VFDMLNRR ddPTM_PC-9_AZD4547_30min_R2 1 VFDMLNRR 8 1 P60842;P60842-2;J3KT12;J3QL43;J3QS69;J3KTB5;J3QR64;Q14240-2;J3KS25;E7EQG2;J3QLN6;J3QKZ9;Q14240;J3KSZ0 P60842 EIF4A1;EIF4A2 Eukaryotic initiation factor 4A-I;Eukaryotic initiation factor 4A-II;Eukaryotic initiation factor 4A-II, N-terminally processed 0 79.71300000000001 0.012861000000000001 1484600.0 8502.6 5983.0 11746.0 22352.0 16603.0 11760.0 9244.0 13245.0 9801.5 13419.0 False True 11206.249934933398 7916.887746058168 11590.240365299942 17199.091734957525 14297.960038641162 11024.645340944187 10066.69809199914 11198.289589821297 10319.587279841164 12949.20489442572 0.865400619288786 0.6113802206856864 0.8950542106480395 1.3281967406633024 1.104157371453443 0.8513762374468256 0.7773989348436814 0.8647858830808876 0.7969282565204806 1.0 13.66057589598752 -10.584114067235621 14.588040094031966 0.9999999987406346 0.9034230889033901 0.025758080413238793 0.1841077499094067 0.0 0.0 0.1991797423241806 0.048308183299170894 2.60546913491406e-11 10.584114067235621 -0.09657690983724454 VFGLNT(ph)LMEIVT(ph)EAGPGSGEGNR ddPTM_PC-9_AZD4547_30min_R2 1 VFGLNTLMEIVTEAGPGSGEGNR 23 0 Q8WXG6-4;Q8WXG6-7;Q8WXG6-2;Q8WXG6 Q8WXG6-4 MADD MAP kinase-activating death domain protein 2 VFGLNT(1)LMEIVT(0.831)EAGPGS(0.169)GEGNR 51.688 0.026766 11082000.0 38405.0 35648.0 59552.0 101870.0 83513.0 68415.0 44467.0 49351.0 35496.0 45790.0 True False 50616.99112637511 47170.51886536543 58762.30156941442 78385.44537581074 71918.66148931168 64136.99923475302 48424.47685600666 41724.936923161265 37372.246093479764 44186.90603739129 1.1455201476098518 1.0675225557872141 1.3298577981379671 1.7739518876809433 1.627601204493783 1.4514933265632994 1.0959010530185007 0.9442828354592946 0.8457764855012725 1.0 15.431331296822675 -7.449151938724594 3.0884339222467516 0.926619593912824 1.4079057955726946 0.5400815227794691 0.19732952966240047 0.23733027296101117 4.41105195014171 0.11258862543236726 0.06778550057521114 3.5550692205844815e-08 7.449151938724594 0.48128620165987057 VFGNEIK ddPTM_PC-9_Lapatinib_30min_R1 1 VFGNEIK 7 0 P19338 P19338 NCL Nucleolin 0 113.89 0.041012 12856000.0 95901.0 103230.0 82114.0 88986.0 84366.0 71199.0 100880.0 79725.0 74645.0 87830.0 False True 94533.43415391071 102990.97727743218 75362.9038892062 95530.32728859398 79403.7577499378 68153.98474297534 106103.07279036913 83429.31455042174 66237.69405330306 103011.29847388114 0.9176996655165937 0.9998027284700802 0.7315984266358385 0.9273771780754324 0.7708257145217026 0.6616165969430626 1.0300139340275565 0.8099045035489532 0.643013873571333 1.0 16.652443058042238 -5.2493398041131165 24.492099416647314 0.8186710202239823 0.9587512082619003 0.15910639911282132 0.1257786595187378 1020.1434371954515 2064972.8403271988 0.031172132646197406 0.08106122092533592 5.631968224894119e-06 5.2493398041131165 0.140080188037918 VFGPGVER ddPTM_PC-9_Lapatinib_30min_R1 1 VFGPGVER 8 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 94.006 0.031633999999999995 4711100.0 17760.0 17978.0 17962.0 19362.0 16314.0 17500.0 16688.0 16427.0 16576.0 14174.0 False True 17506.739143214887 17936.373045565026 16485.2336953251 20785.94606973857 15354.442594558055 16751.565794492486 17552.02298498889 17190.258389711842 14709.036326981728 16623.957014332183 1.053103008394549 1.0789472705025256 0.9916552166919413 1.2503609129774678 0.9236334394585098 1.0076761976736517 1.0558270193947557 1.0340653777491982 0.884809574176622 1.0 14.020976208436817 -6.357748370392823 21.337531975135967 0.9907813560929541 1.085523151199605 0.32153547529049986 0.07700293635383539 19.693112838472103 4357.506333969046 0.023517577315872472 0.02666643408669651 4.387848554618253e-07 6.357748370392823 0.09474179510665093 VFGS(ph)LER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VFGSLER 7 0 Q14680-3;Q14680-4;Q14680-5;Q14680-2;Q14680-8;Q14680-6;Q14680;Q14680-7 Q14680-3 MELK Maternal embryonic leucine zipper kinase 1 VFGS(1)LER 80.455 0.025381 14075000.0 29463.0 25293.0 35871.0 33701.0 35231.0 41504.0 35681.0 35201.0 33383.0 25746.0 True False 34450.5039792246 27803.92188438636 36726.30068152506 31812.842230116195 28327.738457849642 39327.45717638374 32301.037371930557 34277.01104854246 33871.16322056877 30413.545994776126 1.132735524662 0.9141953354982678 1.2075639153630169 1.0460089801952202 0.9314184693463647 1.293090163940064 1.0620608783164787 1.1270310622256914 1.1136867508440658 1.0 14.892426413308339 -6.731233598219265 24.999978688394418 1.123544140802845 1.0479742834631123 0.10495247395444063 0.10584795064992067 474.12398446000833 392410.10926319024 0.03358302177960085 0.03357900103216883 1.8568054483417366e-07 6.731233598219265 -0.07556985733973276 VFIDQNLS(ph)PGK ddPTM_PC-9_AZD4547_30min_R2 4 VFIDQNLSPGK 11 0 F5H452;Q5JSB6;Q5JSB5;Q14186 F5H452 TFDP1 Transcription factor Dp-1 1 VFIDQNLS(1)PGK;VFIDQNLS(1)PGK;VFIDQNLS(1)PGK;VFIDQNLS(1)PGK 174.46 9.6448e-05 65932800.0 391641.0 435431.0 394278.0 352419.0 394437.0 407217.0 474827.0 491644.0 436099.0 426483.0 True False 516174.69136114133 576175.5554327014 389049.6161033312 271174.2443692734 339676.2310282172 381753.6566159244 517085.6831382166 415671.7166551985 459150.30282624654 411551.95998132176 1.254215121183162 1.4000068313581864 0.9453232007958076 0.6589064583280824 0.8253544243687562 0.9275952825816944 1.2564286734576224 1.0100102953562988 1.1156557311671775 1.0 18.650715062252694 -5.266986243812235 24.831065318758 0.96057560800723 1.327110986768562 0.4659819806369947 0.15388760930048112 353.71126894486997 1583429.3622187513 0.04507524042571222 0.09826351140200443 5.407714514980321e-06 5.266986243812235 0.366535378761332 VFIDQNLS(ph)PGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VFIDQNLSPGK 11 0 F5H452;Q5JSB6;Q5JSB5;Q14186 F5H452 TFDP1 Transcription factor Dp-1 1 VFIDQNLS(1)PGK;VFIDQNLS(1)PGK;VFIDQNLS(1)PGK;VFIDQNLS(1)PGK 190.34 0.00012005 60442000.0 325951.0 477636.0 368412.0 351460.0 380314.0 263243.0 397338.0 310105.0 260903.0 265551.0 True False 381128.0664742973 525052.5454936441 377196.3392902906 331768.8356486932 305794.20180689223 249438.0736671834 359699.26816199545 301965.072333407 264718.21279501735 313693.29419943993 1.2149703979071471 1.6737767596645727 1.2024367312438522 1.0576217017816174 0.9748190588112298 0.7951654634625236 1.1466590928568139 0.9626124559150558 0.8438759058289426 1.0 18.258995163552605 -5.630932537495479 2.5750798044530367 0.9612635272034035 1.4464833743683105 0.6494632216097546 0.13989868579797166 0.15470123099020544 2.063279865457608 0.038522698436946404 0.0783365162504958 2.3392005775455733e-06 5.630932537495479 0.48521984716490707 VFIDQNLS(ph)PGK ddPTM_PC-9_Lapatinib_30min_R1 4 VFIDQNLSPGK 11 0 F5H452;Q5JSB6;Q5JSB5;Q14186 F5H452 TFDP1 Transcription factor Dp-1 1 VFIDQNLS(1)PGK;VFIDQNLS(1)PGK;VFIDQNLS(1)PGK;VFIDQNLS(1)PGK 154.23 0.00042842 56409000.0 200771.0 336480.0 259586.0 283097.0 355488.0 289335.0 298632.0 334377.0 290317.0 285195.0 True False 197907.9687231078 335700.9012332699 238243.84111093805 303916.8977639071 334578.8947562989 276960.8165228273 314093.70374240173 349913.3761232533 257618.44228645944 334490.5757515495 0.5916697900335118 1.0036184142976254 0.7122587552000242 0.9085962947716898 1.0002640403382097 0.8280078322103349 0.9390210861297987 1.0461083255845134 0.7701814668698211 1.0 18.351606038044835 -4.750582301495612 24.93511161951475 0.9080757784676304 0.5916690943211841 0.45634438120690524 0.10481319608867294 416.08453913916526 955543.971944393 0.02505556462442271 0.3620319659600197 1.77589669296947e-05 4.750582301495612 -0.31640668414644635 VFITDDFHDMMPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VFITDDFHDMMPK 13 0 P14625 P14625 HSP90B1 Endoplasmin 0 ; 81.92 0.006381399999999999 7685400.0 43523.0 46999.0 52117.0 47572.0 54164.0 41302.0 55862.0 54773.0 44768.0 38622.0 False True 50890.58428156645 51664.750114429866 53359.66693482318 44906.69507050496 43550.95301952732 39136.05041198443 50570.34695414328 53335.26678679061 45422.6473072649 45623.86286841625 1.1154378669850897 1.1324063081514193 1.169556095868466 0.9842808619695428 0.9545652270859352 0.8577978266517391 1.1084187917185615 1.1690212847740407 0.9955896859998096 1.0 15.477500981069666 -5.762246070462507 24.999887029460638 1.01245100025001 1.1384607252478005 0.3543895108232833 0.07984921546325197 27.337822769016476 847271.3200293328 0.024901697394289535 0.03952240006849078 1.728836526028383e-06 5.762246070462507 0.1260097249977905 VFITDDFHDMMPK ddPTM_PC-9_Lapatinib_30min_R1 1 VFITDDFHDMMPK 13 0 P14625 P14625 HSP90B1 Endoplasmin 0 92.792 0.0030142 1328200.0 11060.0 11253.0 9587.8 7155.8 9892.8 9890.9 6378.8 7389.8 11404.0 9317.7 False True 10902.282371844403 11226.944369882256 8799.528093978284 7682.061403049027 9310.924953993132 9467.889263814035 6709.063052291897 7733.157085791237 10119.561430556192 10928.252029945175 0.9976236219635481 1.0273321240321522 0.8052091102827933 0.7029542677089564 0.8520049618621253 0.8663681289441797 0.6139191367391584 0.7076298263071841 0.9260000046509689 1.0 13.415775040449615 -5.27750706133547 7.506108901568658 0.791348195392324 1.0128824007032349 0.3501818349497837 0.10857697880217897 0.1501651237837915 50.910909345293554 0.02804690720137848 0.062277881990760384 5.278286245742384e-06 5.27750706133547 0.22153420531091084 VFLENVIR ddPTM_PC-9_AZD4547_30min_R2 1 VFLENVIR 8 0 P62805 P62805 HIST1H4A Histone H4 0 91.069 0.041476 5010900.0 21210.0 18865.0 20421.0 26984.0 22070.0 21431.0 14876.0 17383.0 10627.0 13218.0 False True 27954.338804593575 24962.74232481818 20150.204197155643 20763.255698644123 19005.96145593027 20090.916182123718 16199.935181369447 14696.856771601624 11188.721524549504 12755.241843246074 2.191596141267635 1.9570575479159575 1.5797586940952606 1.62782140502011 1.490051046424805 1.575110564662629 1.2700609977024735 1.1522209419638436 0.8771861531166463 1.0 13.638802632683804 -2.829434506280951 0.20200707427256923 0.8362811188468281 4.987496552789834 0.9029750655317381 0.12142349054011549 9.595504865327985 0.1840479678483646 0.24900268947461082 11.356410659347151 0.001481035585793321 2.829434506280951 4.151215433943006 up VFLENVIR ddPTM_PC-9_Lapatinib_30min_R1 2 VFLENVIR 8 0 P62805 P62805 HIST1H4A Histone H4 0 ; 119.41 0.015946000000000002 7565800.0 38126.0 33562.0 26105.0 22827.9 25335.0 26836.0 63181.0 26813.0 23298.0 24656.0 False True 37582.31624854788 33484.289251043134 23958.747668214088 24506.73991764203 23844.84511052643 25688.286837771444 66452.20303299285 28058.829865668948 20673.93390118364 28917.75674794513 1.2996276501018167 1.1579144794287162 0.828513355204033 0.8474633814527628 0.8245745103385593 0.8883222534056633 2.2979722670817084 0.9702975963950863 0.7149217721617603 1.0 14.81966802125278 VFLQGPAPVGT(ph)PSFNR ddPTM_PC-9_AZD4547_30min_R2 2 VFLQGPAPVGTPSFNR 16 0 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;H7C0V5 Q8IWZ3-6 ANKHD1;ANKHD1-EIF4EBP3 Ankyrin repeat and KH domain-containing protein 1 1 VFLQGPAPVGT(0.678)PS(0.322)FNR;VFLQGPAPVGT(0.5)PS(0.5)FNR 125.36 7.8367e-05 8915200.0 24347.0 27471.0 32534.0 53826.0 42456.0 38083.0 30801.0 46741.0 31776.0 34288.0 True False 32088.8395509401 36350.463525315696 32102.57790266202 41417.24730341013 36561.71724390464 35701.66398972597 33542.22933055662 39518.25245132781 33455.61448801027 33087.58755645496 0.9698150249300961 1.0986132930753423 0.9702302365770158 1.2517457561009209 1.1049979748907963 1.0790047454747433 1.013740553714469 1.194352788153584 1.0111228094501414 1.0 15.014002486938313 -3.818551892051494 1.3081519545692233 1.090566180017835 7.489575061934986e-10 0.11770733803689437 0.08512938560818356 29.365979872226546 6.291246570387799 0.023726964497282794 76.82168578820108 0.00015186164779885515 3.818551892051494 -1.0905661792688774 VFLQGPAPVGT(ph)PSFNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VFLQGPAPVGTPSFNR 16 0 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;H7C0V5 Q8IWZ3-6 ANKHD1;ANKHD1-EIF4EBP3 Ankyrin repeat and KH domain-containing protein 1 1 VFLQGPAPVGT(0.929)PS(0.071)FNR;VFLQGPAPVGT(0.994)PS(0.006)FNR 136.35 2.4778000000000002e-05 7255300.0 27129.0 32654.0 35319.0 33051.0 38730.0 34233.0 34639.0 34369.0 28563.0 24430.0 True False 31721.403877825887 35895.673317232126 36161.13890805339 31199.25962278776 31141.13452563129 32437.76121624768 31357.743155357293 33466.85016696558 28980.679839112905 28858.965612226402 1.0991871401096505 1.2438309050836025 1.2530296267005963 1.0810941750999512 1.0790800662806161 1.124009836392233 1.0865858318245565 1.159669082276012 1.0042175533427622 1.0 14.816731969993416 -7.146720014646374 0.23558859456288045 0.9792977646632585 1.2402353787373013 0.4327611826415799 0.06150258024373468 3.130916183364464 0.5082137531495462 0.15704948699789292 0.28750582864078145 7.133127475906043e-08 7.146720014646374 0.2609376140740428 VFLQGPAPVGT(ph)PSFNR ddPTM_PC-9_Lapatinib_30min_R1 2 VFLQGPAPVGTPSFNR 16 0 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;H7C0V5 Q8IWZ3-6 ANKHD1;ANKHD1-EIF4EBP3 Ankyrin repeat and KH domain-containing protein 1 1 VFLQGPAPVGT(0.98)PS(0.02)FNR;VFLQGPAPVGT(0.973)PS(0.027)FNR 107.13 0.0023031999999999996 6500100.0 31521.0 24632.0 31600.0 25362.0 25236.0 23440.0 21303.0 22734.0 28769.0 21363.0 True False 31071.504759756557 24574.96611738557 29001.969979527494 27227.206085151804 23751.668095884954 22437.52584130878 22405.96510362045 23790.30463454734 25528.732268999578 25055.566085591796 1.2401038816530363 0.9808186346073979 1.1575060759136102 1.0866729569047258 0.9479597473370738 0.8955106328334557 0.8942510030338129 0.9495017814914969 1.0188846734410792 1.0 14.612843512792898 -6.227720626935921 4.23077580624796 0.9420512692717258 1.1125115348444041 0.5697391144979278 0.07037952832898496 0.15771412970054172 6.548793145910012 0.020948579362492663 0.02654987074813291 5.919422965161701e-07 6.227720626935921 0.17046026557267835 VFLSPYPDS(ph)AFR ddPTM_PC-9_Lapatinib_30min_R1 2 VFLSPYPDSAFR 12 0 Q8TDX9-2;Q8TDX9 Q8TDX9-2 PKD1L1 Polycystic kidney disease protein 1-like 1 1 VFLSPY(0.002)PDS(0.998)AFR;VFLS(0.014)PY(0.076)PDS(0.91)AFR 75.102 0.011398 12810500.0 111555.0 54722.0 65430.0 53505.0 50197.0 52670.0 47675.0 48475.0 65137.0 38799.0 True False 109964.20524331834 54595.294571109625 60050.59796710396 57439.936187447674 47244.51115109909 50417.42687976679 50143.37822443342 50727.32546668789 57800.58513698167 45505.35545358217 2.4165112907531854 1.1997553700420969 1.3196380375131604 1.2622676081728315 1.0382187037147959 1.1079449084008406 1.1019225698738313 1.1147550647842408 1.2701930258723344 1.0 15.473748723358797 -4.760388555995404 5.940879812611192 1.1591206026157845 2.4654542578947605 0.9366930897098164 0.09827113887320314 0.032203149904467154 4.266844537730678 0.025734620192912463 0.17149041881249227 1.7362467427795526e-05 4.760388555995404 1.306333655278976 up VFPGSTTEDYNLIVIER ddPTM_PC-9_Lapatinib_30min_R1 1 VFPGSTTEDYNLIVIER 17 0 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 0 125.97 8.2587e-05 0.0 9398.8 8180.3 10510.0 8581.3 9809.4 8904.3 5915.5 6922.7 9518.2 7968.3 False True 9264.771388471177 8161.35901794613 9645.90836977323 9212.397428377624 9232.430378022418 8523.483845937104 6221.775645236201 7244.353914558847 8446.160084910554 9345.61003790765 0.9913500938827348 0.8732826412446096 1.0321325553546006 0.9857459696060835 0.9878895375019765 0.912030762182903 0.6657431264518253 0.7751611596433308 0.9037569565444366 1.0 13.190073124120923 -7.0099433294081335 23.148170794317636 0.8133513244648662 0.9701142405737851 0.33257051882767985 0.08971704341805731 180.35723491894802 419874.1469712532 0.03217557439080652 0.026733272049355918 9.773647478470032e-08 7.0099433294081335 0.1567629161089189 VFPLS(ph)PASNLR ddPTM_PC-9_AZD4547_30min_R2 3 VFPLSPASNLR 11 0 A0A2R8YH03;Q5VWN6;J3KPH3 A0A2R8YH03 FAM208B Protein FAM208B 1 VFPLS(0.845)PAS(0.155)NLR;VFPLS(0.848)PAS(0.152)NLR;VFPLS(0.715)PAS(0.285)NLR 114.87 0.0014156 12311300.0 19421.5 21581.5 32025.7 41220.2 36954.0 26167.4 23755.7 37759.0 27944.9 29994.6 True False 25597.13300770457 28557.297825765374 31601.01829277937 31717.519735741582 31823.574972471575 24531.148341379507 25869.91127911119 31924.2141655011 29422.01036335595 28944.49818364569 0.884352281573413 0.9866226612248163 1.0917797949813715 1.0958047893766116 1.099468879044261 0.8475237050487258 0.8937764653915572 1.1029458504669816 1.0164975110876189 1.0 14.821001524050546 VFPLS(ph)PASNLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VFPLSPASNLR 11 0 A0A2R8YH03;Q5VWN6;J3KPH3 A0A2R8YH03 FAM208B Protein FAM208B 1 VFPLS(0.998)PAS(0.002)NLR;VFPLS(0.908)PAS(0.092)NLR 124.21 0.00052314 8856900.0 20143.8 19715.6 21181.9 27942.0 24596.0 24608.0 27407.0 25469.0 20692.9 24491.0 True False 23553.747481814637 21672.83447213884 21686.956828803104 26376.500329186274 19776.590363863343 23317.51316009183 24810.810550503094 24800.465736636124 20995.494515379327 28931.02442935068 0.8141345820412509 0.7491208797346156 0.7496090185732093 0.9117029503603464 0.6835772584602945 0.8059691497282787 0.8575849296692167 0.8572273614851992 0.7257086442497102 1.0 14.820329788644035 -14.522878739723144 0.3381709304048433 3.1600568989906064 0.7895061551396787 0.4561700365522108 0.06641710168319574 352.4736909923684 2.9856003765766252 549.4372343476041 0.05299545351781493 3.000000038387736e-15 14.522878739723144 -2.3705507438509277 VFPLS(ph)PASNLR ddPTM_PC-9_Lapatinib_30min_R1 3 VFPLSPASNLR 11 0 A0A2R8YH03;Q5VWN6;J3KPH3 A0A2R8YH03 FAM208B Protein FAM208B 1 VFPLS(0.954)PAS(0.046)NLR;VFPLS(0.991)PAS(0.009)NLR;VFPLS(0.942)PAS(0.058)NLR 148.13 0.00027484 13795700.0 53792.0 48454.0 49623.0 43565.8 40334.0 39971.0 37375.1 37908.0 47144.0 39802.0 True False 53024.91621575535 48341.80774000487 45543.18849031941 46769.77426324846 37961.633419695005 38261.53350695194 39310.199800231174 39669.34406995778 41834.14627167146 46681.72266716868 1.1358817367090834 1.0355617783146578 0.9756107077502947 1.001886211370295 0.8132012113253368 0.8196255690851214 0.8420897420711102 0.8497832085759183 0.8961568657168145 1.0 15.510570180473124 -5.508271291223503 1.046305079629514 0.8616166415492701 1.1260953804048526 0.6561995563138923 0.06046014575679903 0.4288099857093761 0.7778563107325713 0.021721251808764983 0.09728241467911232 3.1026208649865258e-06 5.508271291223503 0.2644787388555825 VFPQSSS(ph)WSGQNIFENIKDSDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VFPQSSSWSGQNIFENIKDSDK 22 1 Q8TDM6-4;Q8TDM6;Q8TDM6-3 Q8TDM6-4 DLG5 Disks large homolog 5 1 VFPQS(0.028)S(0.107)S(0.429)WS(0.429)GQNIFENIKDS(0.006)DK 46.833 0.027013 2281200.0 2914.4 1293.3 2838.1 3974.9 3281.3 3217.7 4257.5 2383.9 3448.9 2946.4 True False 3407.7503579761833 1421.6902768780635 2905.771067554188 3752.1992397996746 2638.3528200091405 3048.9581475628856 3854.1987783692825 2321.3251509508373 3499.333637822235 3480.5589963104353 0.9790813376783922 0.40846607639322463 0.8348575819672786 1.0780450047757246 0.7580255995677491 0.8759966863928846 1.1073505096321952 0.6669403257958152 1.0053941454610313 1.0 11.765103313851174 -5.510969447603952 24.89589228844353 0.9152489515800881 0.6757457188062237 0.20420689478646026 0.18168171648090795 720.7785531816875 1506754.9606372926 0.04520036259296973 0.08657160433490109 3.0834048585840593e-06 5.510969447603952 -0.23950323277386443 VFS(ph)LSEADSHGGHWV ddPTM_PC-9_AZD4547_30min_R2 2 VFSLSEADSHGGHWV 15 0 H7BXG1 H7BXG1 CLEC16A 1 VFS(0.997)LS(0.003)EADSHGGHWV;VFS(0.953)LS(0.047)EADSHGGHWV 115.26 9.227e-05 3820400.0 13429.5 13090.900000000001 23032.0 36915.0 25883.0 23692.0 19400.9 26498.0 20260.6 20516.5 True False 17699.80164904712 17322.27741849788 22726.580631158555 28404.817081064637 22289.592223101197 22210.535494698088 21127.54251547663 22403.34296346431 21331.533953165323 19798.223579736594 0.8940095851409012 0.8749409940105518 1.1479100910052922 1.4347154413458012 1.1258379891170898 1.1218448668005996 1.0671433439665057 1.1315834914802179 1.077446866242993 1.0 14.273083368052426 -5.263061329617856 23.47481690244169 1.1500204214740308 0.8844752497127757 0.46447218811332325 0.10844249442257907 49.600677039973085 717919.4905288975 0.029559749294155356 0.06730756598414152 5.456807964284015e-06 5.263061329617856 -0.26554517176125514 VFS(ph)PVIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VFSPVIR 7 0 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 VFS(1)PVIR 69.598 0.046141 2388500.0 17068.0 15763.0 13499.0 20114.0 17117.0 16909.0 17445.0 14945.0 18242.0 13711.0 True False 19957.275291633767 17327.8464659622 13820.86735524259 18987.077790467833 13763.046725412623 16022.262273406723 15792.483309137331 14552.709585536419 18508.754739526576 16196.69576378372 1.2321818957826454 1.0698383620137983 0.8533140065609214 1.1722809434331345 0.8497441037441225 0.9892303039508197 0.9750435236580649 0.8984986689739951 1.142748805649155 1.0 13.98341190306547 -4.871525131662217 3.6172322450398235 0.9819206716991078 1.2388787493922362 0.35054792655231526 0.10213922247631983 0.25146730564526204 5.551172390124115 0.024009824929262322 0.1489634584339938 1.3442339765700364e-05 4.871525131662217 0.2569580776931284 VFS(ph)QENVCDR ddPTM_PC-9_AZD4547_30min_R2 1 VFSQENVCDR 10 0 Q6NV74;C9JFM2;C9JXD6;C9JK00 Q6NV74 KIAA1211L Uncharacterized protein KIAA1211-like 1 VFS(1)QENVCDR 130.2 0.00022101 29906000.0 14577.0 15881.0 23949.0 25610.0 29594.0 30686.0 22423.0 26542.0 24915.0 22478.0 True False 19212.182779564384 21014.22268011862 23631.420612001373 19706.010170555735 25485.38392962395 28767.19956906574 24418.603560893192 22440.54377448372 26231.95603501939 21691.05206177073 0.8857192691646703 0.9687968393729973 1.0894547919900315 0.9084856794607247 1.1749261334603736 1.3262242646020073 1.1257454682859585 1.0345530364584727 1.2093445703010297 1.0 14.40481240800871 -6.270041505082936 24.89260906678365 1.1549451666687365 0.972544382902049 0.4465933368074967 0.09867835094392712 579.3827662892203 1676599.2348537976 0.03121520515226124 0.03593895575358756 5.369804752388185e-07 6.270041505082936 -0.18240078376668745 VFS(ph)QENVCDR ddPTM_PC-9_Lapatinib_30min_R1 3 VFSQENVCDR 10 0 Q6NV74;C9JFM2;C9JXD6;C9JK00 Q6NV74 KIAA1211L Uncharacterized protein KIAA1211-like 1 VFS(1)QENVCDR;VFS(1)QENVCDR;VFS(1)QENVCDR 128.35 0.00028239 64836000.0 49700.2 40813.6 45650.6 43444.5 51965.0 47700.0 36161.4 51977.8 60516.6 34550.7 True False 48991.466034099576 40719.098616780124 41897.38388441198 46639.55345660351 48908.52086712084 45659.98219413092 38033.660352910905 54392.87834228796 53700.58323995067 40522.74245908611 1.2089869308219683 1.004845579192777 1.033922714552545 1.1509476068578837 1.206940051416842 1.126774236473053 0.9385756749141962 1.3422802861184893 1.3251961733382087 1.0 15.306444194316269 -7.777787250208767 24.999934201449395 1.2503036313198972 1.0975541438503942 0.18002952928638205 0.11946790924061429 352.82358460041416 539546.826107806 0.06368613018846085 0.030737088050763302 1.668064154525255e-08 7.777787250208767 -0.152749487469503 VFS(ph)RMS(ph)NLTVHY(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 VFSRMSNLTVHYR 13 1 Q9NYW8 Q9NYW8 RBAK RB-associated KRAB zinc finger protein 3 VFS(1)RMS(0.905)NLT(0.096)VHY(1)R 73.877 0.014593 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 VFSGLVS(ph)TGLK ddPTM_PC-9_AZD4547_30min_R2 1 VFSGLVSTGLK 11 0 P13639 P13639 EEF2 Elongation factor 2 1 VFS(0.001)GLVS(0.948)T(0.052)GLK 128.57 0.00030349 2353900.0 16668.0 23268.0 21661.0 27916.0 22303.0 22441.0 19229.0 25745.0 18203.0 19941.0 True False 21968.077284062496 30788.925969460364 21373.760986954014 21480.397497900587 19206.61342780304 21037.760722459912 20940.34374849105 21766.701811245694 19165.173417838974 19242.87165956802 1.1416215662977431 1.600017217500454 1.1107365555975355 1.116278166685169 0.998115757751419 1.0932755305261017 1.0882130338420153 1.1311566275724114 0.9959622325033586 1.0 14.232036491540613 -5.42621628339718 8.171431961185506 1.0693991321129015 1.370223277886236 0.5401484321620125 0.11284304872132289 0.20262688836716602 15.444825733557131 0.026992210066156916 0.05635361253168609 3.7478630808505672e-06 5.42621628339718 0.3008241457733345 VFSGLVS(ph)TGLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VFSGLVSTGLK 11 0 P13639 P13639 EEF2 Elongation factor 2 1 VFS(0.001)GLVS(0.77)T(0.229)GLK;VFS(0.002)GLVS(0.822)T(0.175)GLK 113.95 0.0015065 3406400.0 19380.9 30549.0 28168.0 30142.0 34426.0 30589.0 34117.0 28193.0 26002.0 23633.0 True False 22661.703579776477 33581.702828692454 28839.631947734895 28453.241461682483 27680.4724291088 28984.858991143064 30885.19077431001 27452.963622952688 26382.230059048907 27917.475821274922 0.8117389883259716 1.2028918031013758 1.0330315008550033 1.019191048783833 0.9915105723137938 1.0382335128254943 1.106303126114772 0.9833612393435568 0.9450077158818184 1.0 14.768880884680328 -7.9765741796482486 24.73334473736183 0.9697306668062039 1.0351151734222173 0.06129650584612134 0.09317193981750314 478.97049225526473 505704.1108833554 0.048142720603523884 0.023124908827238912 1.0554212166489239e-08 7.9765741796482486 0.06538450661601336 VFSGLVSTGLK ddPTM_PC-9_Lapatinib_30min_R1 1 VFSGLVSTGLK 11 0 P13639 P13639 EEF2 Elongation factor 2 0 152.54 0.0018049 4224200.0 22351.0 22859.0 23467.0 23023.0 23289.0 26097.0 26431.0 21172.0 26184.0 23994.0 False True 22032.270641328585 22806.07138995277 21537.63384523962 24716.188222476558 21919.186807935686 24980.89214507828 27799.467852123755 22155.728412185992 23234.882190256343 28141.33093000466 0.782915019056099 0.8104119683137173 0.7653381390812581 0.8782878209972589 0.7788965938553091 0.887694054244013 0.9878519221876458 0.7873020813156801 0.8256497266617552 1.0 14.780402941269278 -6.774279221569344 24.31495303740737 0.8900404978917633 0.8056437021347908 0.33087850285589515 0.06672441239676946 228.45662574623572 432627.5618866306 0.023604092461027733 0.02095836608179097 1.6815925647428182e-07 6.774279221569344 -0.08439679575697256 VFSPGSS(ph)NS(ph)RPPS(ph)PMDPYAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VFSPGSSNSRPPSPMDPYAK 20 1 H0YNL4 H0YNL4 KMT2C 3 VFS(0.05)PGS(0.05)S(0.953)NS(0.953)RPPS(0.875)PMDPY(0.119)AK 40.961999999999996 0.045018 2495100.0 22736.0 24323.0 27473.0 26504.0 33760.0 25764.0 26661.0 26336.0 27190.0 22526.0 True False 26584.7557435309 26737.626694893024 28128.06051193271 25019.066807127358 27144.970348187777 24412.890485070126 24135.477071075387 25644.70790529856 27587.602311573708 26609.785484282103 0.9990593783341098 1.004804293168257 1.0570570186876336 0.940220537362304 1.0201123328942956 0.9174403341015416 0.9070150935764498 0.9637322300266721 1.0367465129649085 1.0 14.699669259619847 -5.7702811760592105 24.99983147244319 0.9651708802218049 1.0187566400095414 0.23156345354122454 0.042058493204086174 267.65025476096787 756771.2573526442 0.012240714493974231 0.01847472891749577 1.6971445113606861e-06 5.7702811760592105 0.0535857597877365 VGAEDADGIDMAYR ddPTM_PC-9_Lapatinib_30min_R1 2 VGAEDADGIDMAYR 14 0 P49588-2;P49588 P49588-2 AARS Alanine--tRNA ligase, cytoplasmic 0 ; 150.04 0.00029315 3194000.0 13612.9 13011.9 15855.3 15924.5 16308.2 11709.5 11916.8 11691.2 13641.599999999999 11942.4 False True 13418.777549699871 12981.771744998747 14551.73843722792 17095.64085257473 15348.983739154824 11208.711981177694 12533.793594649778 12234.415832823954 12105.139355583608 14006.627927752255 0.95803055659902 0.9268306270402962 1.038918040251187 1.2205393718428121 1.095837186389657 0.8002434303954868 0.8948473293715289 0.8734733224820729 0.8642436579327489 1.0 13.773822050702389 -6.754559319706222 24.99993448264271 0.8791714880002253 1.0503753124047843 0.45963863325268806 0.08733553405384825 156.64812351536665 569208.5260599568 0.031936160656428125 0.03125915815676359 1.7597082911684457e-07 6.754559319706222 0.17120382440455906 VGALDVPASQFLGSAT(ph)SPGPR ddPTM_PC-9_Lapatinib_30min_R1 1 VGALDVPASQFLGSATSPGPR 21 0 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7 P49815 TSC2 Tuberin 1 VGALDVPAS(0.128)QFLGS(0.105)AT(0.384)S(0.384)PGPR 88.163 0.00069062 0.0 11755.0 7800.0 11709.0 7453.0 7378.8 10427.0 9086.8 10236.0 9287.1 9912.3 True False 11587.371544397014 7781.939579230567 10746.331218047075 8001.11848247916 6944.793491278962 9981.06151652417 9557.270041946123 10711.601928355176 8241.08900050144 11625.627847690475 0.9967093129253177 0.6693780053157742 0.9243656651354034 0.6882310862951497 0.5973693276839755 0.8585395685538815 0.8220863567247899 0.9213783606949987 0.7088725966863458 1.0 13.50502101132196 -10.906727503171195 8.127289280687894 1.0000020044566436 0.7953570356103699 0.19355373470226456 0.12320682013627683 4.37682627329452e-06 3.3172835568706933e-07 0.11631451538520152 0.02821013628757165 1.2395741098024088e-11 10.906727503171195 -0.2046449688462737 VGDDVEFEVSSDRR ddPTM_PC-9_AZD4547_30min_R2 2 VGDDVEFEVSSDRR 14 1 O75534;O75534-2;O75534-4;O75534-3;E9PLD4 O75534 CSDE1 Cold shock domain-containing protein E1 0 ; 166.7 0.00016797 9067800.0 31259.0 37756.0 47442.0 65061.0 55492.0 50619.0 40495.0 52719.0 44648.0 47992.0 False True 41198.71177240878 49959.8886411787 46812.88808194787 50062.1916324298 47787.89366164399 47453.785927997764 44098.97655079024 44572.48991210181 47008.00212930143 46311.81468762791 0.8895939848242421 1.078771993240968 1.0108195586309818 1.0809809973998663 1.0318726222233396 1.0246583133930816 0.952218712400643 0.962443173793603 1.0150326098506242 1.0 15.499092668431869 -7.233244740011657 21.393587099263343 0.9792939066229231 1.0251153883953696 0.10061349649416129 0.05228699639007303 231.22364769547454 175447.71730918958 0.019339792699340566 0.01497279831817595 5.84460627477238e-08 7.233244740011657 0.04582148177244649 VGDDVEFEVSSDRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VGDDVEFEVSSDRR 14 1 O75534;O75534-2;O75534-4;O75534-3;E9PLD4 O75534 CSDE1 Cold shock domain-containing protein E1 0 ; 82.20200000000001 0.0060247 11306100.0 54874.0 37401.3 37803.1 60674.0 62863.0 72169.0 54537.0 61714.0 47645.0 44325.0 False True 64163.08438909727 41114.25388741941 38704.46927305511 57274.632487762065 50545.44641582136 68384.33059373639 49370.860546312535 60094.07289138803 48341.71798951565 52360.77162349305 1.2254037211382272 0.7852110007670782 0.7391882906417927 1.0938462270877667 0.9653304343808181 1.3060222084858266 0.9428978797585365 1.1476926528795697 0.9232430403647042 1.0 15.67619873751221 -5.803367271451902 24.99992922092792 1.062460115541907 0.9034611896260463 0.12999171229745698 0.16099687640568705 242.20592268952387 144416.63302205718 0.04419808033990217 0.06555696849706621 1.5726523511123645e-06 5.803367271451902 -0.15899892591586062 VGDDVEFEVSSDRR ddPTM_PC-9_Lapatinib_30min_R1 2 VGDDVEFEVSSDRR 14 1 O75534;O75534-2;O75534-4;O75534-3;E9PLD4 O75534 CSDE1 Cold shock domain-containing protein E1 0 ; 130.56 1.207e-05 8815500.0 29467.0 26554.0 29008.0 24301.0 29230.0 27649.0 25662.0 23844.4 29201.0 25473.0 False True 29046.795176414023 26492.515844472895 26623.07421411816 26088.176605759574 27510.748868391074 26466.516722966997 26990.65279486966 24952.297872261843 25912.07587983791 29875.974109361057 0.9722459615906808 0.8867498595191238 0.8911198716622377 0.8732159329856076 0.9208318620068396 0.8858796244127896 0.9034233560408884 0.8351961271931724 0.8673215402110978 1.0 14.866698132637264 -4.759768129438131 24.872443617892667 0.8906525362544014 0.9722460680246375 0.22669799211181674 0.041222285034045 54.14364221710004 805531.6186504422 0.009584969192466406 0.05943235891713013 1.7387288912898662e-05 4.759768129438131 0.0815935317702361 VGDGDLS(ph)AEEIPENEVSLR ddPTM_PC-9_AZD4547_30min_R2 3 VGDGDLSAEEIPENEVSLR 19 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 VGDGDLS(1)AEEIPENEVSLR;VGDGDLS(0.967)AEEIPENEVS(0.033)LR;VGDGDLS(1)AEEIPENEVSLR 135.27 1.3949000000000001e-07 10029300.0 24201.0 30081.91 31292.9 37899.0 33868.1 35618.6 32753.1 41275.1 38501.7 33144.3 True False 31896.41458792876 39805.299123687866 30877.93569958236 29161.97108371308 29166.098920960216 33391.363311305664 35668.06244883784 34896.98170244115 40536.821259221615 31983.928145339774 0.9972638271004944 1.2445406625104523 0.9654203686072699 0.9117695284705714 0.9118985882042093 1.04400444997157 1.115187049156589 1.0910786675065058 1.2674122163799333 1.0 14.96505951560911 -7.212432084863507 3.4737435358249713 1.1280394080259575 1.0095593605124893 0.19447109923964778 0.10674946597626195 0.42937571389644497 10.584700121469158 0.04741923190594199 0.034312536120195844 6.131516695445725e-08 7.212432084863507 -0.11848004751346819 VGDGDLS(ph)AEEIPENEVSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VGDGDLSAEEIPENEVSLR 19 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 VGDGDLS(1)AEEIPENEVSLR;VGDGDLS(0.999)AEEIPENEVS(0.001)LR;VGDGDLS(1)AEEIPENEVSLR 201.22 2.1845e-15 7105000.0 20611.399999999998 27027.4 29124.6 26230.2 28276.6 26842.1 26374.199999999997 26533.1 22719.8 17900.4 True False 24100.50292629365 29710.501654136075 29819.040919660594 24760.606933455783 22736.003215271532 25434.453023183552 23875.84484332757 25836.63423914328 23052.034093361257 21145.600820511565 1.1397407494288734 1.405044099069364 1.4101770468841754 1.1709578339073536 1.0752119747393156 1.2028247974165736 1.1291164079938378 1.2218444138074025 1.0901574416840605 1.0 14.368069932512899 -6.704855779964169 0.19554126428985313 0.9650643103054934 1.435016813149737 0.40368413992995544 0.0981165804549218 6.372165019171052 0.5858941703575298 0.36271762991142187 0.8920369070601407 1.973077844864379e-07 6.704855779964169 0.4699525028442435 VGDGDLS(ph)AEEIPENEVSLR ddPTM_PC-9_Lapatinib_30min_R1 2 VGDGDLSAEEIPENEVSLR 19 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 VGDGDLS(1)AEEIPENEVSLR;VGDGDLS(1)AEEIPENEVSLR 137.27 2.8057e-05 10175600.0 19904.7 22382.0 26223.0 25606.0 26314.0 23975.0 24260.0 24707.0 24807.0 21718.0 True False 19620.85532792507 22330.175854145968 24067.046163707255 27489.15065911197 24766.262255314487 22949.645138454704 25516.064094908346 25854.97741733795 22012.974430709175 25471.92736258404 0.7702933134438164 0.8766582730974248 0.9448459011805903 1.079193979623664 0.9722963599407043 0.9009779594521637 1.0017327598220596 1.015038126063306 0.8642052922561426 1.0 14.636620506465869 -4.975606525839273 2.084434169338656 0.9758405856966889 0.754911441913918 0.5616603668467093 0.05676068837291441 0.3448364354274248 2.2750643937733566 0.015638868538866424 0.1250825465633858 1.0577754279289266e-05 4.975606525839273 -0.22092914378277084 VGDGDLS(ph)AEEIPENEVSLRR ddPTM_PC-9_AZD4547_30min_R2 3 VGDGDLSAEEIPENEVSLRR 20 1 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 VGDGDLS(1)AEEIPENEVSLRR;VGDGDLS(0.995)AEEIPENEVS(0.005)LRR;VGDGDLS(1)AEEIPENEVSLRR 88.23899999999999 0.00032867 32398800.0 21439.9 19854.6 28734.1 48688.8 33569.299999999996 29338.4 26214.1 31697.3 20492.3 27513.3 True False 28257.34222237651 26272.211172135445 28353.067059472578 37464.34939446131 28908.78214329679 27503.86521009839 28547.10411655935 26799.21061649244 21575.4811421404 26550.067741396768 1.0643039595080868 0.9895346191969187 1.067909405566773 1.4110830058654438 1.088840240442111 1.0359244834322763 1.0752177506518679 1.0093838884903186 0.8126337511561219 1.0 14.69642792156014 -7.843216107853602 1.9936663355897515 0.9067347428842517 1.1131328618249103 0.31554894280265566 0.11614777834065393 0.43290592778801834 3.2994682800722654 0.09390282086223209 0.035835172481233926 1.4347753018550509e-08 7.843216107853602 0.20639811894065863 VGDGDLS(ph)AEEIPENEVSLRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VGDGDLSAEEIPENEVSLRR 20 1 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 VGDGDLS(0.976)AEEIPENEVS(0.024)LRR;VGDGDLS(0.982)AEEIPENEVS(0.018)LRR;VGDGDLS(0.999)AEEIPENEVS(0.001)LRR 63.726000000000006 0.0035267 20284700.0 25888.600000000002 22345.9 25354.6 30318.8 35525.5 28476.9 31515.5 39184.6 34054.5 24500.0 True False 30271.02865684265 24564.253273091737 25959.14982185597 28620.135930875826 28564.533296935588 26983.521233282638 28530.123687538962 38156.04576951557 34552.48263771558 28941.656058106695 1.045932844895501 0.8487507841214627 0.8969476304236809 0.9888907488021643 0.9869695514170319 0.9323419910425073 0.9857806212007533 1.3183781084575457 1.1938668115032507 1.0 14.820859855616092 -7.637149396777414 6.770622922005283 1.1905868005677547 0.9475856337412346 0.5538957348733816 0.08853607005373361 0.1399216156947596 7.735247818521281 0.04072255815115404 0.023258906612294416 2.3059538069412948e-08 7.637149396777414 -0.24300116682652007 VGDGDLS(ph)AEEIPENEVSLRR ddPTM_PC-9_Lapatinib_30min_R1 3 VGDGDLSAEEIPENEVSLRR 20 1 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 VGDGDLS(1)AEEIPENEVSLRR;VGDGDLS(1)AEEIPENEVSLRR;VGDGDLS(0.884)AEEIPENEVS(0.116)LRR 74.0 0.0011886 23588800.0 52188.0 35562.7 46370.899999999994 37007.1 43368.5 46511.9 34749.4 25970.9 45131.2 27670.800000000003 True False 51443.78954989295 35480.35675311577 42558.46359885036 39728.72558606662 40817.65009575157 44522.69446153453 36548.55390187996 27177.602825431764 40048.04900339509 32453.660910976618 1.585145962146089 1.0932620775955495 1.311360949866092 1.224167766312903 1.2577209766170339 1.3718851190213757 1.1261766123130457 0.8374279530430306 1.2340071313757355 1.0 14.98609360908997 -7.484036767025677 6.085946897000495 1.0177266616046077 1.2893978738469103 0.4308092961526995 0.147742169420078 0.18141239925319402 19.033262559919645 0.060283962840330295 0.03903001584725999 3.280675180020876e-08 7.484036767025677 0.2716712122423026 VGDGQRIY(ph)LVT(ph)TYAEFWFYYKSRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VGDGQRIYLVTTYAEFWFYYKSRK 24 3 Q96LW4;Q96LW4-2 Q96LW4 PRIMPOL DNA-directed primase/polymerase protein 2 VGDGQRIY(0.983)LVT(0.341)T(0.341)Y(0.307)AEFWFY(0.019)Y(0.005)KS(0.005)RK 45.88 0.018963999999999998 5130600.0 6472.7 12346.0 35946.0 31894.0 40982.0 41168.0 34675.0 32043.0 32171.0 24568.0 True False 7568.400268347661 13571.629288128495 36803.08896596416 30107.08258174314 32951.871291748575 39009.077607877945 31390.33297473986 31201.905202364887 32641.440013447536 29021.98391981901 0.26078162985884734 0.46763272027245795 1.2681107214325023 1.0373888520137702 1.135410707372278 1.3441216739576092 1.081605346535373 1.0751127589543326 1.1247142891274504 1.0 14.824858523814672 -5.165661599488194 4.308020317363454 1.13813005812581 0.3104495834389976 0.9007128243936448 0.10276001808658543 0.059845040859882334 1.9062231731594241 0.026503230650681244 0.07800962458652468 6.828705768985525e-06 5.165661599488194 -0.8276804746868125 down VGDPPQPLPEEPMEVQGAERAS(ph)PEPQR ddPTM_PC-9_AZD4547_30min_R2 3 VGDPPQPLPEEPMEVQGAERASPEPQR 27 1 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 VGDPPQPLPEEPMEVQGAERAS(1)PEPQR;VGDPPQPLPEEPMEVQGAERAS(1)PEPQR;VGDPPQPLPEEPMEVQGAERAS(1)PEPQR 60.516999999999996 0.001531 95312400.0 53114.5 56844.9 74362.1 60769.6 66561.6 75107.5 63954.2 73473.0 69485.5 70536.0 True False 70003.80614976834 75218.90226239366 73376.00996666704 46760.10760096074 57320.6707768486 70411.0161517828 69645.99990429802 62119.436091577205 73158.36167254024 68066.55610948746 1.0284611144005105 1.1050787135667832 1.0780038562350525 0.6869762519752793 0.8421267954947842 1.0344436412872746 1.0232044029415852 0.9126278695760058 1.0748062757114145 1.0 16.054658496634254 VGDPPQPLPEEPMEVQGAERAS(ph)PEPQR ddPTM_PC-9_Lapatinib_30min_R1 1 VGDPPQPLPEEPMEVQGAERASPEPQR 27 1 P46379-3;P46379;P46379-2;A0A0G2JK23;A0A024RCR6;P46379-5;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 VGDPPQPLPEEPMEVQGAERAS(1)PEPQR 55.718 0.00183 12087000.0 9396.2 17177.0 14923.0 13257.0 16781.0 16137.0 13950.0 16758.0 14986.0 12972.0 True False 9262.208464947957 17137.227711851734 13696.088544445842 14231.96400405559 15793.974572715384 15446.858127184294 14672.262742125777 17536.637858086757 13298.118870423998 15214.192915896492 0.6087873682257816 1.1263974242068382 0.9002178834038271 0.9354399594332327 1.038107946969248 1.0152926423750486 0.9643799591101226 1.152649894412977 0.8740600926999886 1.0 13.893130183193799 -4.749901998168571 24.99995915510511 1.0008039243623919 0.6087865053700562 0.656890769667971 0.08497872903849808 305.8202038083958 662629.7716968148 0.01996793597892652 0.31107389953497994 1.7786807375043e-05 4.749901998168571 -0.39201741899233566 VGDST(ph)PVSEKPVSAAVDANASESP ddPTM_PC-9_AZD4547_30min_R2 1 VGDSTPVSEKPVSAAVDANASESP 24 1 Q9H8Y8-2;Q9H8Y8;Q9H8Y8-3 Q9H8Y8-2 GORASP2 Golgi reassembly-stacking protein 2 1 VGDS(0.159)T(0.709)PVS(0.127)EKPVS(0.005)AAVDANASESP 49.18600000000001 0.024125 18105000.0 48669.0 51287.0 71175.0 104920.0 118530.0 106190.0 74416.0 118180.0 94097.0 102040.0 True False 64144.729621912535 67864.51977805191 70231.17299508122 80732.31499784102 102074.15547672925 99549.92251316864 81038.87983710592 99917.99650623482 99070.77531716722 98467.61065855889 0.6514297360615099 0.6892065251118498 0.7132413646007024 0.8198870111491194 1.0366267120127068 1.0109915519161192 0.8230003682948304 1.0147295728816375 1.0061255132989855 1.0 16.5873616307516 -5.9622485490031885 2.617523010905465 0.9757878396329327 0.6808174786830126 0.8390459013826312 0.058599560368207494 0.11083451552750938 1.5385948600354835 0.01875954627490321 0.029103125614639788 1.0908158781438095e-06 5.9622485490031885 -0.29497036094992013 VGDSTPVS(ph)EKPVSAAVDANASESP ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VGDSTPVSEKPVSAAVDANASESP 24 1 Q9H8Y8-2;Q9H8Y8;Q9H8Y8-3 Q9H8Y8-2 GORASP2 Golgi reassembly-stacking protein 2 1 VGDS(0.037)T(0.447)PVS(0.51)EKPVS(0.006)AAVDANASESP 44.053999999999995 0.028406 3941200.0 17903.0 18626.0 16381.0 24383.0 38011.0 32430.0 36021.0 34355.0 38527.0 31488.0 True False 20933.62429963203 20475.066185054377 16771.58516528845 23016.899560752594 30563.01741424663 30729.31371024781 32608.830110543757 33453.21765213139 39090.384489076896 37196.52514112915 0.5627844058069066 0.5504564232107416 0.4508911814115582 0.618791660603324 0.8216632413454213 0.826133989496498 0.8766633438693805 0.8993640541745475 1.0509149535006876 1.0 15.182880232178038 -6.512689113718029 0.8760816313953694 0.9734052180970719 0.5015666712939002 0.909308395652862 0.058812943716727635 0.17578103024611497 0.2963534035758092 0.03547083816527289 0.043443790518999006 3.0712197101100366e-07 6.512689113718029 -0.4718385468031717 VGDSTPVS(ph)EKPVSAAVDANASESP ddPTM_PC-9_Lapatinib_30min_R1 1 VGDSTPVSEKPVSAAVDANASESP 24 1 Q9H8Y8-2;Q9H8Y8;Q9H8Y8-3 Q9H8Y8-2 GORASP2 Golgi reassembly-stacking protein 2 1 VGDS(0.05)T(0.175)PVS(0.773)EKPVS(0.002)AAVDANASESP 63.138000000000005 0.0010182000000000001 15148000.0 63259.0 59545.0 79921.0 54685.0 116240.0 117330.0 109150.0 102270.0 124860.0 104910.0 True False 62356.915059720144 59407.12721093392 73350.20388398158 58706.71732381231 109402.99173663283 112312.06940958883 114801.25292494823 107021.83755499033 110796.9519659109 123043.55371621202 0.5067873381123265 0.4828138119933587 0.5961320334843114 0.47712143830967074 0.8891403769835857 0.9127830432191978 0.9330131441889767 0.8697882523925291 0.9004693754331357 1.0 16.90880955104423 -6.275188306753099 10.61011062174538 0.9116683648142455 0.5190752757660474 0.9513361116776115 0.04450734651963035 0.08944145583042225 67.76426972359606 0.013141196728344028 0.015303093855997018 5.306543067083208e-07 6.275188306753099 -0.3925930890481981 VGDSTPVSEKPVSAAVDANASES(ph)P ddPTM_PC-9_AZD4547_30min_R2 4 VGDSTPVSEKPVSAAVDANASESP 24 1 Q9H8Y8-2;Q9H8Y8;Q9H8Y8-3 Q9H8Y8-2 GORASP2 Golgi reassembly-stacking protein 2 1 VGDSTPVSEKPVSAAVDANASES(1)P;VGDSTPVSEKPVSAAVDANAS(0.001)ES(0.999)P;VGDSTPVSEKPVSAAVDANASES(1)P;VGDSTPVSEKPVSAAVDANAS(0.035)ES(0.965)P 123.85 9.6546e-09 82533000.0 260699.0 254408.0 349424.0 430443.0 375234.0 355173.0 269057.0 395451.0 297670.0 336275.0 True False 343595.8591239382 336640.4107804053 344790.4094504141 331211.01662805624 323139.23611031 332963.97616319475 293002.5517675254 334343.13450995984 313404.22849465086 324502.11460414436 1.0588401235630962 1.0374059077891318 1.0625213024297828 1.0206744477831708 0.995800093643467 1.0260764450468154 0.9029295606438655 1.0303265201147316 0.9658002656684328 1.0 18.307868353952358 -6.2424798042383625 1.2719247717809623 0.980531939063143 1.0530677110732418 0.4389233094017516 0.033831728141356564 0.41716416216094115 1.3745509301604713 0.012995967335208304 0.018988705571416357 5.721635610466229e-07 6.2424798042383625 0.07253577201009886 VGDSTPVSEKPVSAAVDANASES(ph)P ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VGDSTPVSEKPVSAAVDANASESP 24 1 Q9H8Y8-2;Q9H8Y8;Q9H8Y8-3 Q9H8Y8-2 GORASP2 Golgi reassembly-stacking protein 2 1 VGDSTPVSEKPVSAAVDANAS(0.016)ES(0.984)P;VGDSTPVSEKPVSAAVDANAS(0.026)ES(0.974)P;VGDSTPVSEKPVSAAVDANAS(0.001)ES(0.999)P;VGDSTPVSEKPVSAAVDANAS(0.002)ES(0.998)P 104.77 7.720699999999999e-07 40931300.0 223412.0 228718.0 272443.0 284721.0 307409.0 289180.0 301222.0 263090.0 254787.0 205700.0 True False 261231.23901186298 251423.6114953968 278939.07436583133 268769.0054479364 247174.41320397097 274014.89172770473 272688.0715015739 256184.16626689688 258512.7778653521 242991.7816796957 1.0750620338107153 1.034700061695155 1.1479362488626066 1.1060826979005383 1.0172130575584184 1.127671437418829 1.1222110872087967 1.0542914846584852 1.0638745725405467 1.0 17.890547995138455 -8.654886175960716 1.399145825597786 1.000860296002433 1.0882072154549842 0.3063984695359284 0.03944292452560088 0.7664228011670056 3.0992085041830766 0.03843900515929884 0.011420232676578018 2.2136748145877827e-09 8.654886175960716 0.08734691945255113 VGDSTPVSEKPVSAAVDANASES(ph)P ddPTM_PC-9_Lapatinib_30min_R1 4 VGDSTPVSEKPVSAAVDANASESP 24 1 Q9H8Y8-2;Q9H8Y8;Q9H8Y8-3 Q9H8Y8-2 GORASP2 Golgi reassembly-stacking protein 2 1 VGDSTPVSEKPVSAAVDANAS(0.01)ES(0.99)P;VGDSTPVSEKPVSAAVDANAS(0.001)ES(0.999)P;VGDSTPVSEKPVSAAVDANAS(0.001)ES(0.999)P;VGDSTPVSEKPVSAAVDANAS(0.035)ES(0.965)P 97.38799999999999 2.3818000000000002e-06 74932000.0 559911.0 495636.0 553994.0 455172.0 547254.0 534170.0 421730.0 466977.0 564281.0 410762.0 True False 551926.5664648982 494488.3852937861 508446.75179868314 488646.86728928116 515065.5956627606 511324.79431108874 443565.11585926224 488674.45620335214 500725.73163764365 481761.66439403896 1.1456423523426522 1.0264170477652157 1.0553906410096137 1.0142917201681094 1.0691294756933627 1.0613646375417487 0.9207148443767927 1.0143489868958504 1.0393640022550523 1.0 18.87796007185498 VGDTEKPEPERS(ph)PPNR ddPTM_PC-9_AZD4547_30min_R2 1 VGDTEKPEPERSPPNR 16 2 Q9NZ63 Q9NZ63 C9orf78 Uncharacterized protein C9orf78 1 VGDTEKPEPERS(1)PPNR 65.565 0.0090277 146610000.0 82812.0 89120.0 90455.0 116560.0 102150.0 106880.0 105010.0 112830.0 92077.0 117190.0 True False 109144.49340339476 117926.29716341368 89255.50759775283 89688.8928340483 87968.23573734853 100196.7767040913 114355.68656867486 95394.71607546498 96944.00224107881 113087.2137698599 0.9651355777984871 1.042790720827216 0.7892625931999157 0.7930949029885133 0.7778795922620378 0.8860133110008219 1.0112167658617568 0.8435499725866414 0.8572498959817543 1.0 16.787076294360375 -9.926381832617562 24.86931162093435 0.9999999999882263 0.8835996426468121 0.13069171725804185 0.08879609512779392 0.0 0.0 0.09352933194738729 0.022684194983090246 1.184726675964858e-10 9.926381832617562 -0.11640035734141418 VGDTEKPEPERS(ph)PPNR ddPTM_PC-9_Lapatinib_30min_R1 1 VGDTEKPEPERSPPNR 16 2 Q9NZ63 Q9NZ63 C9orf78 Uncharacterized protein C9orf78 1 VGDT(0.004)EKPEPERS(0.996)PPNR 47.037 0.03688 136070000.0 133240.0 105920.0 101660.0 105850.0 101980.0 117570.0 103710.0 89253.0 93402.0 67498.0 True False 131339.9731667766 105674.74874770547 93301.9072189482 113634.56210524878 95981.73690039411 112541.80516905607 109079.59634307271 93400.02021409557 82882.08319333644 79164.93936456829 1.659067438451929 1.334868056439163 1.1785761218015556 1.4354152610657844 1.2124273405728456 1.4216117143825693 1.3778775960497138 1.1798154708863258 1.0469544202093057 1.0 16.272574009297884 -1.5228818452147148 0.04716974368394988 0.2854753670772285 3.080026902484501 0.5414711843366253 0.1280996387144836 482.43636860162206 1.72885520504777 25.212478664780736 100.47393068379506 0.029999785864883645 1.5228818452147148 2.7945515354072725 VGDVT(ph)PQVK ddPTM_PC-9_AZD4547_30min_R2 4 VGDVTPQVK 9 0 E7ETY2;Q13428-6;Q13428-7;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 VGDVT(1)PQVK;VGDVT(1)PQVK;VGDVT(1)PQVK;VGDVT(1)PQVK 109.72 0.0057453 166026000.0 620858.0 612670.0 769670.0 1016280.0 1003840.0 965550.0 733930.0 925130.0 749520.0 900220.0 True False 818277.9293513607 810703.5960851501 759463.6729065556 781992.3473694806 864474.1435396934 905174.0058629798 799248.3481891948 782172.4158725085 789138.0970245922 868703.5718056438 0.9419529928379701 0.9332338698689383 0.8742495110593045 0.9001831841718694 0.9951313331690816 1.0419825994056067 0.9200472682849883 0.9003904683466698 0.9084089471214319 1.0 19.728504443832946 -4.4143024350129325 16.442843569386593 0.9390603699507118 1.1188966961777316 0.0 0.05098311187389355 32755729.09332789 30526776.831460867 0.013821504751503707 218079526.18347436 3.852100107871296e-05 4.4143024350129325 0.17983632622701973 VGDVT(ph)PQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 VGDVTPQVK 9 0 E7ETY2;Q13428-6;Q13428-7;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 VGDVT(1)PQVK;VGDVT(1)PQVK;VGDVT(1)PQVK;VGDVT(1)PQVK;VGDVT(1)PQVK 117.79 0.0044909 112453500.0 358178.0 355120.0 411479.0 393529.0 500786.0 431604.0 414226.0 373702.0 333935.0 285895.0 True False 418810.46106203477 390373.96669368213 421290.2199027972 371480.8459682316 402660.57822238083 408969.92644458235 374987.51454346406 363892.7184699986 338818.1676320473 337725.50035642553 1.2400913186005633 1.1558912971679454 1.247433846298784 1.0999490579662528 1.1922717644875047 1.2109536473051858 1.110332249556854 1.0774807294265816 1.003235370957978 1.0 18.365491590260774 -7.7955623435232635 1.406309503373499 0.9984883020951764 1.1888212497557273 0.7681523662847215 0.04138937142636069 0.2020474604486602 0.7347258275432025 0.03325198086858092 0.012597860611627173 1.6011707817510263e-08 7.7955623435232635 0.19033294766055098 VGDVT(ph)PQVK ddPTM_PC-9_Lapatinib_30min_R1 4 VGDVTPQVK 9 0 E7ETY2;Q13428-6;Q13428-7;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 VGDVT(1)PQVK;VGDVT(1)PQVK;VGDVT(1)PQVK;VGDVT(1)PQVK 103.34 0.0070584 162839000.0 677776.0 621264.0 679202.0 607404.0 653212.0 550043.0 472097.0 469787.0 558834.0 452324.0 True False 668110.7899511051 619825.5013783469 623360.63335554 652074.5164003442 614791.3544242034 526518.9431028584 496539.8726716382 491615.0190617623 495892.2301370956 530507.6007161563 1.259380240828203 1.1683630932744722 1.1750267715562175 1.2291520715633089 1.1588737910526987 0.9924814317308301 0.9359712697826318 0.9266879841082557 0.9347504719398331 1.0 19.017013895580533 -6.770304377493275 2.8111568713096777 0.9443159031018615 1.2029748197460184 0.9391178126334486 0.030902183195025867 0.057681230098599025 0.9357562857330003 0.011323284001779394 0.01045767152111703 1.697053846762503e-07 6.770304377493275 0.25865891664415686 VGEDEDGS(ph)DEEVVHNEDIHFEPIVSLPEVEVK ddPTM_PC-9_AZD4547_30min_R2 2 VGEDEDGSDEEVVHNEDIHFEPIVSLPEVEVK 32 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 VGEDEDGS(1)DEEVVHNEDIHFEPIVSLPEVEVK;VGEDEDGS(0.993)DEEVVHNEDIHFEPIVS(0.007)LPEVEVK 59.917 0.00064254 19006100.0 60610.0 59423.0 58240.3 73261.0 64776.0 67432.0 67535.0 59693.0 60843.0 69677.0 True False 79882.71923368306 78630.32266990039 57467.99556846401 56371.80832116695 55782.97051514905 63215.46638014866 73545.48416736926 50468.818458678914 64059.03676655363 67237.62943802805 1.188065669497016 1.1694392459563558 0.854699906120745 0.8383967250529561 0.8296391616031528 0.9401798800538238 1.0938143533920255 0.75060377470915 0.9527259854631835 1.0 16.036981240674855 -5.254101230737435 24.111419815977673 0.9011719011667895 1.1787525369408802 0.5796922573838008 0.09226000901437001 233.97449967178062 768775.9519497878 0.023796944440594492 0.060164136596129306 5.570558883110745e-06 5.254101230737435 0.27758063577409076 VGEDEDGS(ph)DEEVVHNEDIHFEPIVSLPEVEVK ddPTM_PC-9_Lapatinib_30min_R1 4 VGEDEDGSDEEVVHNEDIHFEPIVSLPEVEVK 32 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 VGEDEDGS(0.991)DEEVVHNEDIHFEPIVS(0.009)LPEVEVK;VGEDEDGS(1)DEEVVHNEDIHFEPIVSLPEVEVK;VGEDEDGS(0.997)DEEVVHNEDIHFEPIVS(0.003)LPEVEVK;VGEDEDGS(0.996)DEEVVHNEDIHFEPIVS(0.004)LPEVEVK 62.16 0.00033615 24913000.0 61296.3 49863.6 52156.1 51954.3 52418.4 51471.0 50284.7 52358.9 55845.0 41672.2 True False 60422.20352163526 49748.143897810434 47868.026786368144 55775.19253646413 49335.25277053951 49269.70531476124 52888.19572107326 54791.68563956193 49555.14802607949 48875.18424528384 1.2362552582595254 1.01786099972832 0.9793932754532197 1.1411761080337226 1.0094131312722379 1.0080720119129878 1.0821073421564984 1.1210532806298117 1.0139122499750222 1.0 15.576814520521998 -4.756340392323179 24.993575985758387 1.0456306309833583 1.2362555538914475 0.5562993595795714 0.05207415899153294 124.3157439728564 609287.3383896061 0.012981691610493916 0.10587154676872307 1.7525063799437303e-05 4.756340392323179 0.1906249229080892 VGEEEHVY(ph)SFPNK ddPTM_PC-9_AZD4547_30min_R2 1 VGEEEHVYSFPNK 13 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 VGEEEHVY(0.899)S(0.101)FPNK 88.134 0.0097924 11580000.0 43559.0 28140.0 34210.0 46241.0 42314.0 39129.0 30792.0 30875.0 31212.0 39087.0 True False 57409.85591651537 37235.70469230767 33756.35304758307 35580.85186632831 36439.431492806245 36682.25744437117 33532.42834799195 26103.978186918266 32861.80259943912 37718.57602715688 1.522057881378688 0.9871980497221966 0.8949530073266535 0.943324367301421 0.9660871467303096 0.9725249812707782 0.8890162853403861 0.6920722078193976 0.8712365645982779 1.0 15.20298759115797 -4.7483348851409755 3.229473937162089 0.8992883546799169 1.6394653110932702 0.8375933353440275 0.0811754054856394 0.1580066770212778 2.366718944187696 0.02265310085730633 0.31021677306831036 1.785110542527648e-05 4.7483348851409755 0.7401769564133533 VGEEEHVY(ph)SFPNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VGEEEHVYSFPNK 13 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 VGEEEHVY(0.683)S(0.317)FPNK;VGEEEHVY(0.844)S(0.156)FPNK 140.39 0.00010526 15326200.0 74810.0 59581.0 57002.0 66600.0 64671.0 59528.0 60888.0 40004.0 57078.0 40765.0 True False 87473.85543514905 65495.80792288868 58361.14386128884 62868.61792011334 51999.18179465793 56406.246886945155 55120.24784905433 38953.93738774165 57912.65776903293 48155.37180443758 1.8164921618793985 1.3600934946338252 1.2119342385787744 1.3055369642960564 1.079821001192356 1.1713386227400542 1.144633418529123 0.8089219525899704 1.202620924706394 1.0 15.555409121405338 -1.5228787452803467 0.519997026872115 1.0499310823315628 27.57339039836134 0.7855672382148372 0.1159729821274404 52.0525789788377 0.5225255740981412 0.060254911431714166 1522.614107925523 0.029999999999999367 1.5228787452803467 26.52345931602978 VGEEEHVY(ph)SFPNK ddPTM_PC-9_Lapatinib_30min_R1 1 VGEEEHVYSFPNK 13 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 VGEEEHVY(0.796)S(0.204)FPNK 96.015 0.0048865 13456000.0 40882.0 30797.0 37590.0 27377.0 33398.0 37039.0 29598.0 22839.0 34169.0 24687.0 True False 40299.015183159376 30725.691438662037 34499.49530159617 29390.395906994774 31433.595302994374 35454.9283121261 31130.439615873725 23900.18331786869 30320.527404478667 28954.11505664023 1.3918234110877221 1.0611856511088749 1.1915230437576156 1.01506800845065 1.08563481361816 1.224521220654437 1.0751646028544184 0.825450312368898 1.0471923367426514 1.0 14.821480783028584 -1.5228787452803376 0.3956645666788167 1.0090218847319417 5.784364098578806 0.45020582769845974 0.106441320318178 75.30024331170256 1.0055893727270533 0.08162398499587557 279.3291515146058 0.029999999999999995 1.5228787452803376 4.775342213846864 VGEEEHVYS(ph)FPNK ddPTM_PC-9_AZD4547_30min_R2 1 VGEEEHVYSFPNK 13 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;A0A1B0GU60;F5H836;P49023-3 A0A1B0GTU4;P49023-3 PXN Paxillin 1 VGEEEHVY(0.115)S(0.885)FPNK 178.68 0.00012085 10747000.0 60004.0 41640.0 52258.0 68868.0 59405.0 60946.0 39063.0 47009.0 35238.0 49739.0 True False 79084.02383926597 55099.31568541904 51565.02477522937 52991.54659999352 51157.64115494058 57135.03698547484 42539.53132494182 39744.83920935516 37100.6087401972 47997.6527493733 1.64766440251182 1.1479585464965985 1.0743238850550385 1.1040445431091508 1.0658363112477107 1.1903714809516566 0.8862835761379446 0.8280579764366519 0.7729671476628953 1.0 15.550676234349076 -1.5228787452803376 0.503702355265849 0.9276342511844539 21.848522646160745 0.740684276806511 0.11842687402707666 62.80166220041484 0.6605086810238784 0.07131087186454534 1392.8030949208955 0.029999999999999995 1.5228787452803376 20.92088839497629 VGEEFEEQTVDGRPCK ddPTM_PC-9_AZD4547_30min_R2 2 VGEEFEEQTVDGRPCK 16 1 P29373 P29373 CRABP2 Cellular retinoic acid-binding protein 2 0 ; 115.82 0.00022022 5962900.0 54287.0 45453.0 72218.0 88173.0 83599.0 74536.0 58469.0 85461.0 69917.0 65705.0 False True 71549.13676025321 60144.79336814001 71260.3421335971 67846.07710927026 71992.72187377966 69875.25213712722 63672.62773053848 72254.96614841212 73612.66988161555 63404.68794904558 1.1284518396771044 0.9485859060843365 1.1238970561745312 1.0700482772471642 1.1354479329925218 1.1020518260933896 1.0042258670480047 1.1395839721895478 1.1609972742200623 1.0 15.952301892324316 VGEEFEEQTVDGRPCK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VGEEFEEQTVDGRPCK 16 1 P29373 P29373 CRABP2 Cellular retinoic acid-binding protein 2 0 164.2 9.6298e-16 0.0 12004.0 8244.8 11335.0 12742.0 21694.0 14553.0 13252.0 14877.0 13540.0 10620.0 False True 14036.040110192866 9063.289256015043 11605.269388226881 12028.10705012137 17443.216431682045 13789.815060907684 11996.674623828476 14486.494513484457 13737.996884836628 12545.32193212626 1.1188266180917328 0.722443736800857 0.9250674834025521 0.9587722909939523 1.3904160073416034 1.099199776260385 0.9562667812539111 1.154732783412055 1.0950692982741357 1.0 13.614861872530314 -6.0204099939508025 24.952214882766835 1.1202928062418502 0.9087747015466598 0.2957942078619591 0.1398982430135789 862.6960002400297 1054687.9852682017 0.04084106223695347 0.05340868702389987 9.540914545510945e-07 6.0204099939508025 -0.2115181046951904 VGEEFEEQTVDGRPCK ddPTM_PC-9_Lapatinib_30min_R1 1 VGEEFEEQTVDGRPCK 16 1 P29373 P29373 CRABP2 Cellular retinoic acid-binding protein 2 0 81.703 0.009062100000000002 5831700.0 12113.0 15753.0 16208.0 19238.0 20424.0 14913.0 11703.0 12939.0 21174.0 13776.0 False True 11940.26639874785 15716.524896361436 14875.440804689286 20652.826696086686 19222.70047512896 14275.205753900931 12308.924076781223 13540.193176141816 18789.161147895193 16157.163244633834 0.7390075979280266 0.9727279881003403 0.9206715671223884 1.2782458395316372 1.1897323920096718 0.8835217876901786 0.7618245783875025 0.8380303504477388 1.1628997530946843 1.0 13.979886302134837 -9.996954899366868 15.068749061130159 0.999999990317766 0.9730805901831165 0.002291832973861707 0.1745051838367809 0.0 0.0 0.1813427151240498 0.04398206875839711 1.0070362421673749e-10 9.996954899366868 -0.02691940013464944 VGEFCHNR ddPTM_PC-9_AZD4547_30min_R2 4 VGEFCHNR 8 0 P22314;P22314-2;Q5JRR9;Q5JRS2;Q5JRS0 P22314;Q5JRS0 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 ;;; 132.08 0.0023106 15272300.0 77917.0 68460.0 101355.0 132069.0 106763.0 96574.0 91917.0 124486.0 88879.0 100264.0 False True 102692.98522571992 90588.35619173358 100010.96647581954 101622.53249570969 91940.80031352461 90535.21251329432 100097.43493317657 105249.54910369928 93576.96248992522 96753.78787798634 1.0613846494074564 0.9362771027215201 1.0336646106500837 1.0503209716591477 0.950255306071001 0.9357278355599462 1.0345583064862207 1.0878080477472025 0.9671658809671894 1.0 16.562030522933767 VGEFCHNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VGEFCHNR 8 0 P22314;P22314-2;Q5JRR9;Q5JRS2;Q5JRS0 P22314;Q5JRS0 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 ;;; 132.08 1.3817999999999999e-05 12959400.0 87762.0 92088.0 100190.0 105982.0 121686.0 102956.0 111140.0 100494.0 92719.0 81589.6 False True 102618.37322148817 101229.88805160993 102578.90957269083 100044.17213828005 97842.50183026008 97556.8061163205 100612.01461608015 97856.13898219464 94074.83996788543 96381.14861708188 1.0647141551423767 1.050307964826108 1.0643047011219215 1.0380056014454777 1.0151622307281696 1.0121980025773447 1.0438972357115945 1.0153037226291297 0.9760709570046803 1.0 16.556463373969265 -6.072360550022772 0.35903162959135587 0.9935552435693569 1.0836416693106516 0.689567652594941 0.015332427719038061 1.6462870788248618 0.32938582306397957 0.017351564551318255 0.05948676905275109 8.465243402771269e-07 6.072360550022772 0.09008642574129477 VGEFCHNR ddPTM_PC-9_Lapatinib_30min_R1 4 VGEFCHNR 8 0 P22314;P22314-2;Q5JRR9;Q5JRS2;Q5JRS0 P22314;Q5JRS0 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 ;;; 180.93 0.00081665 19338200.0 128499.0 123338.0 139208.0 124708.0 122459.0 123900.0 113184.0 111851.0 142296.0 101781.0 False True 126666.58069616965 123052.41843886442 127762.85559842004 133879.44233369257 115256.20238365716 118601.0858250067 119044.1137064348 117048.00579215096 126269.12603669098 119373.71023534265 1.0610927686376612 1.0308167367527514 1.0702763225381733 1.1215152990533024 0.9655074149612347 0.9935276837017737 0.9972389521255722 0.9805174486190752 1.0577632695486652 1.0 16.86512562017471 -6.272294609160757 24.993349606159832 0.9977474197107514 1.0680140330132546 0.5712689530706772 0.03043087361884781 552.0714217363718 1271100.5933381098 0.009599930544149928 0.010999374060780347 5.342018538642282e-07 6.272294609160757 0.07026661330250317 VGEFSGANK ddPTM_PC-9_AZD4547_30min_R2 1 VGEFSGANK 9 0 P10599-2;P10599 P10599-2 TXN Thioredoxin 0 107.69 0.011451000000000001 17260000.0 28864.0 29933.0 34548.0 48203.0 46091.0 43003.0 41906.0 46999.0 35080.0 47483.0 False True 38042.151591503476 39608.256878281616 34089.87094673783 37090.54307892612 39692.060238571954 40314.01561195774 45635.55281732103 39736.384479578046 36934.2571827606 45820.634622700396 0.830240608947321 0.8644196485803134 0.7439851330616244 0.8094724873267202 0.8662485922643195 0.879822288449611 0.9959607323882924 0.8672159346281053 0.8060616682175475 1.0 15.483709819874322 -6.540987569599204 2.401995018482393 0.9075410398007163 0.8114759306721372 0.3676595457569233 0.060557390180491964 0.3566812476388233 4.15114759513814 0.02221544305688325 0.02356175256298124 2.877480772971628e-07 6.540987569599204 -0.09606510912857913 VGEFSGANK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VGEFSGANK 9 0 P10599-2;P10599 P10599-2 TXN Thioredoxin 0 ;; 117.81 0.0084574 42677000.0 89465.0 102384.0 110093.0 106244.0 105980.0 92957.0 110915.0 85090.0 89672.0 84310.0 False True 104609.65748570538 112548.00688771634 112718.03465002737 100291.49312769536 85213.97978379553 88082.17127855397 100408.32824493943 82856.47766030737 90983.28335724311 99594.73560240735 1.0503532827610298 1.1300597989136676 1.1317669951955052 1.0069959272553273 0.85560726948439 0.8844058950082186 1.008169032606101 0.8319363183118346 0.9135350659542683 1.0 16.60378186560763 -5.989063907149285 4.018776766850771 0.9108170382552403 1.104938722083666 0.6898858134362511 0.05661539245315501 0.11367666985641713 4.225524817231892 0.01640769538610626 0.02386935104234906 1.0255010109828602e-06 5.989063907149285 0.19412168382842565 VGEFSGANK ddPTM_PC-9_Lapatinib_30min_R1 4 VGEFSGANK 9 0 P10599-2;P10599 P10599-2 TXN Thioredoxin 0 ;;; 128.12 0.0061754 154558000.0 186870.0 182785.0 206321.0 181696.0 184312.0 159264.0 201301.0 161028.0 165741.0 171934.0 False True 184205.19953223865 182361.7725627772 189358.08380209174 195058.5299600881 173471.1305313341 152452.649982517 211723.38080664238 168509.94874161578 147073.50324989602 201652.5628123455 0.9134780979880573 0.9043364984777307 0.9390313773413591 0.9673000295146573 0.8602475867998932 0.756016426750732 1.0499414331950176 0.8356449647427904 0.729341106300544 1.0 17.621512215579394 -6.281499014885669 23.43430374795179 0.8667588585143295 0.9297004218702767 0.0875469895705756 0.0926684120640896 926.3490929513594 1082186.4169980001 0.02878868424463773 0.032695451262187376 5.229991525047949e-07 6.281499014885669 0.06294156335594714 VGEVIVTK ddPTM_PC-9_Lapatinib_30min_R1 2 VGEVIVTK 8 0 P10809 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 ; 114.89 0.016852000000000002 18003200.0 137713.0 124519.0 135936.0 122623.0 113946.0 104810.0 126574.0 103407.0 143248.0 109240.0 False True 135749.18736652896 124230.68390592458 124759.86680813473 131641.1044783367 107243.92030645543 100327.5206240432 133127.38238866147 108211.66672581308 127113.90177168661 128121.98844684985 1.0595307566807175 0.9696281287224985 0.9737584338217646 1.027466917069795 0.8370453940538436 0.7830624691378646 1.039067407573744 0.844598714378396 0.9921318214977484 1.0 16.967158568390644 -6.243055270118896 24.838447134219297 0.9077222966342139 1.0024670955383426 0.23698355321760223 0.07949553932746484 1098.9330443226784 1484748.1605813499 0.023183749388112625 0.02987167538256092 5.714059125555505e-07 6.243055270118896 0.09474479890412868 VGFQYEGTYK ddPTM_PC-9_AZD4547_30min_R2 1 VGFQYEGTYK 10 0 P11413;P11413-2;P11413-3 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 119.53 0.0036033000000000003 5696800.0 16626.0 14887.0 12098.0 19872.0 20048.0 16900.0 21562.0 16703.0 20721.0 14747.0 False True 21912.722157716766 19698.931618848044 11937.572615307232 15290.817419339477 17264.681253669693 15843.240328397678 23480.97622887119 14121.935146756136 21816.269757240094 14230.712018637456 1.5398190989332408 1.3842548140282127 0.8388598265268118 1.0744941925121976 1.2131986952626654 1.1133132556999503 1.6500211794124562 0.9923561890832406 1.533041335434805 1.0 13.796720226941517 VGFQYEGTYK ddPTM_PC-9_Lapatinib_30min_R1 1 VGFQYEGTYK 10 0 P11413;P11413-2;P11413-3 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 148.32 0.00069618 19088000.0 59963.0 59773.0 61583.0 52964.0 50825.0 55605.0 64094.0 51267.0 58739.0 64985.0 False True 59107.91662413256 59634.59929094214 56519.88345725451 56859.149242724605 47835.5734257946 53226.90377158597 67412.47370564952 53649.05197938498 52123.19527090851 76217.57066293045 0.7755156207422992 0.7824258733550309 0.7415597606385504 0.7460110411309514 0.6276187106165554 0.6983547666059851 0.8844741851426732 0.7038934921797239 0.6838737422033763 1.0 16.217836004382846 -11.027008528903412 5.999635660552616 1.0002767658443112 0.7386917472798502 0.5905871282223036 0.06539358677633288 0.000253147592268071 2.0922686592663363e-05 0.06620950463179007 0.016041409106471435 9.397048559653167e-12 11.027008528903412 -0.26158501856446104 VGGPLAVLGPS(ph)RSSEDLAGPLPSSVSSSSTTSSKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VGGPLAVLGPSRSSEDLAGPLPSSVSSSSTTSSKPK 36 2 Q9NRF2-2;Q9NRF2-3;Q9NRF2 Q9NRF2-2 SH2B1 SH2B adapter protein 1 1 VGGPLAVLGPS(0.333)RS(0.333)S(0.333)EDLAGPLPSSVSSSSTTSSKPK 47.479 0.0022529 6681500.0 7513.0 3055.1 11990.0 26693.0 32067.0 31772.0 23752.0 38865.0 31874.0 21144.0 True False 8784.802511486088 3358.390137547491 12275.887072328223 25197.477749873644 25783.701544885582 30105.820388590582 21502.03861041157 37844.83493087138 32340.09695031633 24977.239824188106 0.3517123018124218 0.13445801702617302 0.49148293241113783 1.0088175445820182 1.0322878639262811 1.2053301565946422 0.8608652822234133 1.5151728212267161 1.2947826572493406 1.0 14.608326436480368 -5.728705300089539 2.002874865183747 1.1668880339134666 0.22875550179248755 0.8223518106023223 0.1748442685769534 0.12828869228302744 1.0476198535371322 0.05447807279954136 0.11115754977375056 1.8676465929196736e-06 5.728705300089539 -0.938132532120979 down VGGPLAVLGPSRS(ph)SEDLAGPLPSSVSSSSTTSSKPK ddPTM_PC-9_AZD4547_30min_R2 2 VGGPLAVLGPSRSSEDLAGPLPSSVSSSSTTSSKPK 36 2 Q9NRF2-2;Q9NRF2-3;Q9NRF2 Q9NRF2-2 SH2B1 SH2B adapter protein 1 1 VGGPLAVLGPS(0.131)RS(0.435)S(0.435)EDLAGPLPSSVSSSSTTSSKPK;VGGPLAVLGPS(0.152)RS(0.418)S(0.418)EDLAGPLPS(0.002)S(0.003)VS(0.002)S(0.001)S(0.001)S(0.001)T(0.001)T(0.001)S(0.001)SKPK 72.11 9.341200000000001e-07 21386900.0 28087.8 27298.7 43588.0 94647.0 67009.0 45323.0 35978.0 46702.0 36851.0 54561.0 True False 37019.13613746646 36122.47091982584 43009.99464010674 72827.59643157314 57705.957009534766 42488.945645205196 39179.972301378715 39485.27900519698 38798.868627192445 52650.835997075876 0.703106331294007 0.6860759233116833 0.8168910108567969 1.3832182348560969 1.0960121699252723 0.8069947008546066 0.7441472022126049 0.7499459079318306 0.7369088807886595 1.0 15.684168818288766 -6.9674407888665755 24.40577831277863 0.7852923307041354 0.9422552796848591 0.08877289510888453 0.20199218397275373 366.4206687619853 274660.6546501152 0.07969748330276549 0.07028598043620242 1.0778521966154448e-07 6.9674407888665755 0.15696294898072372 VGGS(ph)DEEASGIPSR ddPTM_PC-9_AZD4547_30min_R2 4 VGGSDEEASGIPSR 14 0 H7C446;A8MV53;A0A0A6YYI3;A0A0B4J1V8;Q9NQ55-2;Q9NQ55;Q9NQ55-3 H7C446 PPAN;PPAN-P2RY11 Suppressor of SWI4 1 homolog 1 VGGS(1)DEEASGIPSR;VGGS(1)DEEASGIPSR;VGGS(0.996)DEEAS(0.003)GIPSR;VGGS(0.997)DEEAS(0.002)GIPS(0.001)R 166.79 1.9376e-05 388344000.0 56235.0 48554.6 67090.0 83015.0 82375.0 74687.0 60238.7 57913.4 48265.4 67256.7 True False 74116.56023933616 64248.924913046234 66200.34276417266 63877.17431896473 70938.65314600164 70016.81008325657 65599.82760217531 48964.21474753919 50816.610508232974 64902.063404346176 1.1419754065072287 0.9899365527528635 1.0200036684771958 0.9842086825653557 1.093010752278351 1.078807150506834 1.010751032574758 0.7544323274051761 0.7829737275322133 1.0 15.985976725507237 -7.6639746296387115 5.942476638884052 0.8277933240137413 1.0455078043967927 0.5921915033668765 0.07588803575432133 0.12884337898323367 6.506020075972412 0.035462614930720004 0.020053222939745822 2.1678307401903352e-08 7.6639746296387115 0.2177144803830514 VGGS(ph)DEEASGIPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VGGSDEEASGIPSR 14 0 H7C446;A8MV53;A0A0A6YYI3;A0A0B4J1V8;Q9NQ55-2;Q9NQ55;Q9NQ55-3 H7C446 PPAN;PPAN-P2RY11 Suppressor of SWI4 1 homolog 1 VGGS(1)DEEASGIPSR;VGGS(1)DEEASGIPSR;VGGS(0.753)DEEAS(0.227)GIPS(0.02)R;VGGS(1)DEEASGIPSR 192.54 5.6645e-07 234033000.0 64147.0 63019.0 78503.0 80657.0 101395.0 86478.0 96506.0 90773.0 81576.0 55231.0 True False 75005.82013899885 69275.10984193817 80374.80924428534 76138.04978352225 81527.3776200977 81942.94144418156 87364.25303706528 88390.30493194348 82768.89467337022 65243.943091644534 1.1496211998352452 1.061786068702673 1.231912196529681 1.1669749891813768 1.2495777195069393 1.2559471049915065 1.3390400533326072 1.3547664464084666 1.268606567158416 1.0 15.993556355143959 -5.764387187586006 1.0813632028112665 1.2699525303828696 1.1059801182888698 0.16485285484433232 0.09873020820026744 0.7911002740385316 1.7770287004624798 0.035694232143040835 0.10144696270237467 1.7203341575183653e-06 5.764387187586006 -0.16397241209399982 VGGS(ph)DEEASGIPSR ddPTM_PC-9_Lapatinib_30min_R1 5 VGGSDEEASGIPSR 14 0 H7C446;A8MV53;A0A0A6YYI3;A0A0B4J1V8;Q9NQ55-2;Q9NQ55;Q9NQ55-3 H7C446 PPAN;PPAN-P2RY11 Suppressor of SWI4 1 homolog 1 VGGS(1)DEEASGIPSR;VGGS(1)DEEASGIPSR;VGGS(1)DEEASGIPSR;VGGS(1)DEEASGIPSR;VGGS(0.999)DEEAS(0.001)GIPSR 194.67 1.4279000000000002e-07 303006000.0 111983.8 104149.3 124617.0 112370.9 138991.1 140492.6 109425.7 112083.2 121634.5 104216.0 True False 110386.890476686 103908.14869476386 114371.47129553085 120635.03084433329 130815.9167650163 134484.0590022466 115091.22732193793 117290.99465183831 107934.74174193156 122229.59674090907 0.9031109765556526 0.8501062873914138 0.9357101254122998 0.9869543388909661 1.0702474707685383 1.1002577328902867 0.9415986830578981 0.9595956935083477 0.8830491519228488 1.0 16.89923413685475 -5.56266722554872 3.0649468403331865 0.9957053270201932 0.8774741993365982 0.376690936696655 0.05919804261424978 0.27750365118552306 5.297146221688273 0.018369370154794253 0.03759957975271403 2.7373654058722745e-06 5.56266722554872 -0.118231127683595 VGGS(ph)SVDLHR ddPTM_PC-9_AZD4547_30min_R2 6 VGGSSVDLHR 10 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 VGGS(0.851)S(0.149)VDLHR;VGGS(0.853)S(0.147)VDLHR;VGGS(0.959)S(0.041)VDLHR;VGGS(0.955)S(0.045)VDLHR;VGGS(0.849)S(0.151)VDLHR;VGGS(0.958)S(0.042)VDLHR 134.18 6.291e-05 801631100.0 302684.0 337902.0 548137.0 824689.0 763659.0 746883.0 553315.0 764897.0 578224.0 653536.0 True False 398931.2157816873 447122.21346624556 540868.3452336461 634569.6923680386 657638.1295638551 700180.2879405109 602558.9630868122 646699.7442344687 608787.7401723077 630655.9035608758 0.6325655774079015 0.7089796685350237 0.8576282917193644 1.0062059021172471 1.0427843866213404 1.1102413915212388 0.9554480655529906 1.0254399278322845 0.9653247305462554 1.0 19.26649353569705 -5.408107212253524 1.748592967275241 1.0214592602218286 0.6370134503698567 0.9165834012486982 0.04180120523715613 0.10594061773841001 0.5972477894128692 0.012850765898361488 0.044059707830804755 3.907444226314757e-06 5.408107212253524 -0.38444580985197196 VGGS(ph)SVDLHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 VGGSSVDLHR 10 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 VGGS(0.909)S(0.091)VDLHR;VGGS(0.771)S(0.229)VDLHR;VGGS(0.961)S(0.039)VDLHR;VGGS(0.957)S(0.043)VDLHR;VGGS(0.959)S(0.041)VDLHR;VGGS(0.984)S(0.016)VDLHR;VGGS(0.852)S(0.148)VDLHR;VGGS(0.857)S(0.143)VDLHR 143.97 6.519e-05 895932000.0 818672.0 1021688.0 1621120.0 1388808.0 1772710.0 1403949.0 1363912.0 1135370.0 1274216.0 1205496.0 True False 957257.0000909554 1123114.4325392372 1659773.6489318379 1310997.590336286 1425360.2010052155 1330323.442929038 1234712.3814922413 1105567.7405239507 1292848.9984201603 1424042.882098917 0.6722107965457057 0.7886802052504648 1.16553628391125 0.9206166519395738 1.0009250556446425 0.9341877689583726 0.8670471914949508 0.7763584611261416 0.9078722380288239 1.0 20.441561160052615 -5.010178431398578 23.16954089106786 0.9390327638060758 0.7013277938470623 0.4639574805346387 0.09626928935145108 162.346688144609 369574.41701203684 0.025603106198812616 0.0802498466372561 9.76835802112084e-06 5.010178431398578 -0.23770496995901347 VGGS(ph)SVDLHR ddPTM_PC-9_Lapatinib_30min_R1 5 VGGSSVDLHR 10 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 VGGS(0.873)S(0.127)VDLHR;VGGS(0.702)S(0.298)VDLHR;VGGS(0.948)S(0.052)VDLHR;VGGS(0.703)S(0.297)VDLHR;VGGS(0.848)S(0.152)VDLHR 134.49 6.3245e-05 625468800.0 788759.0 566556.0 667775.0 554955.0 629892.0 643423.0 445647.0 405654.0 777491.0 380758.0 True False 777511.152019313 565244.174391096 612873.117186045 595768.2419756112 592842.9909753193 615905.2981822707 468720.4210924825 424502.1657527346 689921.7762368087 446571.5129718561 1.7410675097592117 1.265741674003104 1.3723963562016765 1.3340936998217299 1.3275432349682401 1.3791862675779016 1.0495976735578794 0.9505804858168094 1.5449301090557674 1.0 18.768531698268404 -1.5228787452803376 0.2724729229085826 1.121439027602045 4.544519651613151 0.38766371804617583 0.1824816337873012 57.80525600523785 0.8092965584995999 0.20848223123993526 93.33548676823132 0.029999999999999995 1.5228787452803376 3.4230806240111065 VGGSS(ph)VDLHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VGGSSVDLHR 10 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 VGGS(0.412)S(0.588)VDLHR 83.226 0.013462 0.0 10801.0 10686.0 17880.0 15590.0 22572.0 18368.0 20412.0 17799.0 15252.0 11150.0 True False 12629.395970525924 11746.83545868629 18306.327010277604 14716.54284346195 18149.17863445778 17404.74974498401 18478.427589917523 17331.795109599374 15475.031646050837 13171.40673664857 0.958849439778172 0.8918436499270419 1.3898535954661135 1.1173098771989283 1.3779225710158118 1.3214040149983708 1.4029198216544718 1.3158651506353378 1.174895890428513 1.0 13.685121816533828 -5.253822216382234 24.99851426922732 1.2798547940454164 0.9253465005358816 0.5320252132661576 0.1256526761638998 392.9809070721391 1289703.09277967 0.030425063150828834 0.07729070331210539 5.5741388624542564e-06 5.253822216382234 -0.3545082935095347 VGGSS(ph)VDLHR ddPTM_PC-9_Lapatinib_30min_R1 1 VGGSSVDLHR 10 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 1 VGGS(0.391)S(0.609)VDLHR 114.76 0.000669 8283800.0 95762.0 72975.0 88956.0 66019.0 86626.0 83810.0 49314.0 54931.0 106230.0 46945.0 True False 94396.41631940001 72806.03087107051 81642.38106009032 70874.25749292805 81530.82899326883 80225.64167065221 51867.23762474487 57483.29479547459 94265.25874850793 55059.38069971945 1.7144474768834623 1.3223183760118373 1.4828060182032947 1.2872331034644056 1.4807799862101294 1.4570749007909019 0.9420236291362637 1.044023635299761 1.7120653656205809 1.0 15.748700762340382 -7.2179387153923305 24.410331426751917 1.178196703395879 1.4457781541463983 0.274333592835726 0.2249079462017613 499.78719750272205 280454.93430842395 0.08418040430792269 0.06520536755791458 6.054263022626564e-08 7.2179387153923305 0.2675814507505194 VGGSSVDLHR ddPTM_PC-9_Lapatinib_30min_R1 2 VGGSSVDLHR 10 0 O60716;O60716-21;O60716-10;O60716-9;O60716-17;O60716-5;O60716-2;O60716-3;A0A669KB05;O60716-11;O60716-19;O60716-13;C9JZR2;O60716-18;O60716-24;A0A669KB62;O60716-7;O60716-6;O60716-4;O60716-23;O60716-12;O60716-8;O60716-14;O60716-15;O60716-20;O60716-22;O60716-16 O60716 CTNND1 Catenin delta-1 0 ; 115.57 0.00093391 1368900.0 78363.0 62321.0 94396.0 61389.0 83992.0 90302.0 70517.0 61312.0 101807.0 56293.0 False True 77245.5292499858 62176.699553490806 86635.1252590976 65903.75184770075 79051.75569462549 86439.9939642433 74168.0252176691 64160.779350460354 90340.42358476273 66023.17004429242 1.1699760735233515 0.9417405966992927 1.3121927529529012 0.9981912683606141 1.1973335367204072 1.3092372557430068 1.1233635883874193 0.971791861969326 1.36831393470136 1.0 16.010684789503177 -1.6176885155034526 18.319927839077998 1.139729831496481 1.1624984445961406 0.0 0.14905981473382163 0.0 0.0 0.03209332711017707 0.0 0.024116344799746423 1.6176885155034526 0.022768613099659607 VGGTSDVEVNEK ddPTM_PC-9_AZD4547_30min_R2 1 VGGTSDVEVNEK 12 0 P10809 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 159.94 0.0025399999999999997 5015900.0 12302.0 15260.0 19250.0 18285.0 19808.0 21414.0 18651.0 24917.0 19592.0 19409.0 False True 16213.780102504015 20192.496574435492 18994.732422273446 14069.675750433886 17058.001110968136 20074.979194811127 20310.902868225417 21066.65018569855 20627.593122139282 18729.496817639825 0.8656815642390107 1.0781120694827093 1.0141613844309911 0.7512041507267176 0.9107559736950627 1.0718376147673172 1.0844339848519684 1.1247846320066401 1.1013426213731374 1.0 14.1930245205374 -6.788772958811834 7.185844734302062 1.0854707151231402 0.9278844702970133 0.4359560101026939 0.08639705094752942 0.18683314405534482 34.187522252550764 0.03230999969516713 0.02907737806986258 1.6263987849903808e-07 6.788772958811834 -0.15758624482612693 VGGTSDVEVNEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VGGTSDVEVNEK 12 0 P10809 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 96.015 0.020346 3862100.0 14391.0 16835.0 13943.0 15899.0 15333.0 13356.0 14899.0 14385.0 16733.0 12396.0 False True 16827.112064793862 18506.267541361023 14275.453999121955 15008.23057525346 12328.608718861475 12655.58784810576 13487.658860581087 14007.40899216736 16977.68846927411 14643.296673317995 1.1491341355840359 1.2638047260957206 0.9748797909103148 1.0249215671905645 0.841928494238993 0.8642581059745856 0.9210807621727264 0.9565748276950978 1.1594170935708545 1.0 13.837952766425014 -5.275109008305228 19.46945001445153 0.9584977345465668 1.2064691641415541 0.539243555543348 0.0878745824933233 27.384559122992776 39005.24062815939 0.024002527810612698 0.05079457153057803 5.307512084802634e-06 5.275109008305228 0.2479714295949873 VGGTSDVEVNEK ddPTM_PC-9_Lapatinib_30min_R1 3 VGGTSDVEVNEK 12 0 P10809 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 ;; 183.33 0.0025026 27084000.0 101179.5 112990.0 114559.0 98862.0 89696.0 86998.0 98853.4 76416.0 115209.0 99020.0 False True 99736.66177595191 112728.37859708517 105140.40123052816 106132.64127396398 84420.2576291209 83277.29834224313 103971.54535859899 79966.5663303233 102232.94921544619 116135.47506414373 0.8587958306526542 0.9706627413787496 0.9053254500612945 0.9138692653157444 0.7269118896056012 0.717070286200212 0.8952608606558299 0.688562786574527 0.8802904466441549 1.0 16.825449203587517 -6.228449167548449 21.156371608228195 0.8012591849826436 0.9158536807283233 0.18462124837436744 0.09288183484149884 135.77483423226553 87069.99891873046 0.025842494641286382 0.03335534265514066 5.909501299026014e-07 6.228449167548449 0.1145944957456797 VGGVS(ph)PEEHPAPEVSTPFPPLPPEPEGGGEEK ddPTM_PC-9_AZD4547_30min_R2 2 VGGVSPEEHPAPEVSTPFPPLPPEPEGGGEEK 32 0 Q8TE77;Q8TE77-3 Q8TE77 SSH3 Protein phosphatase Slingshot homolog 3 1 VGGVS(0.806)PEEHPAPEVS(0.1)T(0.094)PFPPLPPEPEGGGEEK;VGGVS(0.765)PEEHPAPEVS(0.117)T(0.117)PFPPLPPEPEGGGEEK 68.763 0.00058406 3479800.0 14590.3 11835.3 17774.800000000003 14871.7 17842.1 19251.9 19361.3 23062.0 18073.1 19318.8 True False 19229.711902907206 15660.829273094132 17539.094538152007 11443.259330474582 15365.032392064051 18048.07564960234 21084.418192191995 19498.297812039164 19028.40716903508 18642.454692185074 1.0315010668079194 0.840062616843004 0.9408146527776947 0.6138279276747607 0.8241957749536643 0.9681169109756829 1.1309893756121394 1.0459082848254344 1.0207028786295935 1.0 14.186304214814283 -6.935422853064379 4.097470742052208 1.0534167056625074 0.8424489237791556 0.4487112149682104 0.10414187432974399 0.20269725531678479 6.8489040506250145 0.03988670057480742 0.034389589198972226 1.160318313751974e-07 6.935422853064379 -0.21096778188335186 VGGVS(ph)PEEHPAPEVSTPFPPLPPEPEGGGEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VGGVSPEEHPAPEVSTPFPPLPPEPEGGGEEK 32 0 Q8TE77;Q8TE77-3 Q8TE77 SSH3 Protein phosphatase Slingshot homolog 3 1 VGGVS(0.999)PEEHPAPEVS(0.001)T(0.001)PFPPLPPEPEGGGEEK;VGGVS(0.614)PEEHPAPEVS(0.193)T(0.193)PFPPLPPEPEGGGEEK 59.152 0.00049065 9336900.0 29240.0 35316.0 31217.0 40235.0 43069.0 35671.0 39412.0 36948.0 29600.0 30308.0 True False 34189.7544836754 38821.939084687 31961.331671131786 37980.76339363001 34629.93862340343 33800.34996479338 35678.610041829736 35978.154149641974 30032.844002301656 35802.600482004025 0.9549517080710572 1.0843329412398586 0.8927097819946618 1.0608381202008168 0.9672464613515986 0.9440752769280805 0.9965368314450619 1.0049033775556664 0.8388453240260437 1.0 15.127776759391983 -8.204046601572811 24.99997824217988 0.9194209298089235 0.9887507828807197 0.15752475499265672 0.06361138476263899 401.8636741450366 175049.75968618455 0.03954203186122557 0.014945475486646787 6.251056127897974e-09 8.204046601572811 0.06932985307179618 VGGVS(ph)PEEHPAPEVSTPFPPLPPEPEGGGEEK ddPTM_PC-9_Lapatinib_30min_R1 1 VGGVSPEEHPAPEVSTPFPPLPPEPEGGGEEK 32 0 Q8TE77;Q8TE77-3 Q8TE77 SSH3 Protein phosphatase Slingshot homolog 3 1 VGGVS(0.953)PEEHPAPEVS(0.023)T(0.023)PFPPLPPEPEGGGEEK 51.533 0.0035345999999999997 4152000.0 27730.0 34271.0 44302.0 38117.0 47456.0 47384.0 46313.0 43172.0 52968.0 45579.0 True False 27334.56511494082 34191.64760510397 40659.66057066541 40920.2513345845 44664.73138208577 45357.49677749892 48710.86052875064 45177.928727134575 47002.186062232606 53457.26941980006 0.5113348551397644 0.6396070726433272 0.7606011495156065 0.7654758983897526 0.8355221257437137 0.8484813622129929 0.9112111609409778 0.8451222671392397 0.8792477912241332 1.0 15.706098526611866 -4.167910454786448 0.4168425432568399 0.9175361463439775 9.974168204844144e-18 0.923132815836945 0.036790984765394115 2.2943176165684207 0.21176927164742465 0.02722773594811043 1.1591607990219703 6.793436889783306e-05 4.167910454786448 -0.9175361463439775 VGGVSPEEHPAPEVS(ph)TPFPPLPPEPEGGGEEK ddPTM_PC-9_Lapatinib_30min_R1 1 VGGVSPEEHPAPEVSTPFPPLPPEPEGGGEEK 32 0 Q8TE77;Q8TE77-3 Q8TE77 SSH3 Protein phosphatase Slingshot homolog 3 1 VGGVS(0.203)PEEHPAPEVS(0.398)T(0.398)PFPPLPPEPEGGGEEK 77.211 3.2475e-07 3969000.0 5839.0 10584.0 10945.0 10149.0 14847.0 12117.0 11346.0 12025.0 13440.0 12400.0 True False 5755.73478925854 10559.493398279026 10045.144348921782 10895.39131607152 13973.728650325087 11598.784156106583 11933.440363595631 12583.72539942077 11926.245670525725 14543.323478038592 0.395764750605327 0.7260715485167183 0.6907048697700106 0.7491679142339303 0.9608346174398423 0.7975332580356572 0.8205442436603942 0.8652578909093958 0.8200495360317858 1.0 13.828069374899593 -4.457206609953137 0.7625212520952455 0.8627220148790339 5.0021189949779295e-17 0.7580178482079211 0.07798507540192946 2.0822434980747704 0.6570110164001655 0.029354911649917388 1.7175028351172161 3.489742560164115e-05 4.457206609953137 -0.8627220148790339 down VGHFDPVTR ddPTM_PC-9_AZD4547_30min_R2 1 VGHFDPVTR 9 0 Q9UNE7;Q9UNE7-2;H3BTA3 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 0 81.95 0.013836000000000001 1423600.0 7465.2 8142.7 9592.8 13052.0 11181.0 10001.0 9876.9 10258.0 6226.6 9264.9 False True 9838.978314193877 10774.668535822802 9465.59320417582 10043.063051389836 9628.711148108583 9375.635889012148 10755.924965909375 8672.861805389715 6555.725364144157 8940.538671016078 1.1004905494218609 1.2051475791668689 1.058727393558723 1.1233174443893388 1.076972149264726 1.0486656603149194 1.2030511093004401 0.9700603201355046 0.7332584316643986 1.0 13.126146041640217 -7.977639285982657 6.194867137203596 0.8606974712616342 1.1128971242502435 0.6311816666691982 0.07810469796128071 0.08774111909195866 11.721414418926422 0.042282041982524096 0.019174593541344348 1.0528359697118727e-08 7.977639285982657 0.25219965298860925 VGHFDPVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VGHFDPVTR 9 0 Q9UNE7;Q9UNE7-2;H3BTA3 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 0 ; 83.647 0.01197 0.0 10611.2 15397.400000000001 11866.1 11155.6 13989.7 13781.7 13305.7 9212.4 14090.8 13048.8 False True 12407.466579246799 16925.95211412844 12149.032826434854 10530.587898943179 11248.518710901739 13058.96339070374 12045.28777107414 8970.584261344633 14296.851292825413 15414.44414575604 0.8049246837527299 1.0980578964820182 0.7881589962995693 0.6831636482877975 0.7297388478324547 0.8471900295087307 0.7814286170280419 0.5819596332193688 0.9274970383386594 1.0 13.911995245470694 -5.414793331232063 9.41875764016568 0.7717555640694066 0.9509760496108417 0.17950542753553433 0.13066847228559972 0.48246783375781027 38.88888788958684 0.03206797503960083 0.06685095324971893 3.847748422222088e-06 5.414793331232063 0.1792204855414351 VGIDT(ph)PDIDIHGPEGK ddPTM_PC-9_AZD4547_30min_R2 4 VGIDTPDIDIHGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VGIDT(1)PDIDIHGPEGK;VGIDT(1)PDIDIHGPEGK;VGIDT(1)PDIDIHGPEGK;VGIDT(1)PDIDIHGPEGK 157.73 2.9361999999999998e-05 157816700.0 119908.4 110424.8 131695.7 224757.0 198274.0 159041.9 247629.0 414214.0 339362.0 267993.0 True False 158036.77695034104 146117.45712534257 129949.32896955842 172942.74611103447 170747.07755836548 149096.98485118276 269667.50127906236 350206.7439908066 357299.98249874596 258610.64664072017 0.6110992683526161 0.5650094418902214 0.5024902518808246 0.6687379207217966 0.66024767261643 0.5765307298361874 1.0427548315661697 1.3541853304954534 1.3816135845139117 1.0 17.980422144556336 -7.4071564859315915 3.0379871236163014 1.2718082229053298 0.5954959084381617 0.8822870914196814 0.10834835062903787 0.07882311509334239 1.3872731342841655 0.05082777633153726 0.03137933529830825 3.916007492505081e-08 7.4071564859315915 -0.6763123144671681 VGIDT(ph)PDIDIHGPEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VGIDTPDIDIHGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VGIDT(1)PDIDIHGPEGK;VGIDT(1)PDIDIHGPEGK;VGIDT(1)PDIDIHGPEGK;VGIDT(1)PDIDIHGPEGK 173.87 1.6116e-05 33248300.0 87339.0 88380.0 74587.0 85060.0 160006.0 125446.0 135405.0 240371.0 140028.0 103172.0 True False 102123.76767611921 97153.78231692812 76365.43695277277 80294.36396824058 128653.97291268158 118867.39092493827 122578.45815269386 234061.5159441264 142075.6445930504 121876.26689089726 0.837929896290142 0.7971509531375741 0.6265816873200961 0.6588187020867607 1.0556113687651072 0.9753120435773397 1.0057615094366583 1.9204847827646097 1.165736760875975 1.0 16.895057690039287 -7.09240770161737 1.3575521107902049 1.3813108972881802 0.7545289604369185 0.4465584045772024 0.2578755321365179 0.3550006011006881 1.3109372739128413 0.14298141205792372 0.09642335242153194 8.083367025194924e-08 7.09240770161737 -0.6267819368512617 VGIDT(ph)PDIDIHGPEGK ddPTM_PC-9_Lapatinib_30min_R1 4 VGIDTPDIDIHGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VGIDT(1)PDIDIHGPEGK;VGIDT(1)PDIDIHGPEGK;VGIDT(1)PDIDIHGPEGK;VGIDT(1)PDIDIHGPEGK 287.43 2.9009999999999998e-96 28160000.0 296091.0 242474.3 189589.0 173036.0 253861.6 206587.8 289796.0 192950.9 252995.0 318335.0 True False 291868.6880435601 241912.86565592696 174001.72425470408 185761.64467117455 238929.95979910856 197752.5213736829 304800.2188972816 201916.10321589131 224500.03894454264 373358.78059527546 0.7817378436318297 0.6479367252866697 0.46604428045666785 0.4975419203346445 0.6399473434591886 0.5296581509570778 0.816373511857186 0.5408098421951145 0.6012984041425368 1.0 18.51020313495944 -11.368636321437203 2.3638237040602483 1.1688881576022718 0.6088928113539908 0.5297447001703626 0.10917338557351527 14073263.624102894 8044936.853327568 13421245.711984958 0.02828803478688796 4.279210776244527e-12 11.368636321437203 -0.5599953462482811 VGIDTPDIDIHGPEGK ddPTM_PC-9_AZD4547_30min_R2 1 VGIDTPDIDIHGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 120.21 8.046e-05 4573800.0 27022.0 28820.0 41011.0 50109.0 47003.0 34446.0 30487.0 39330.0 33234.0 39229.0 False True 35614.4339074836 38135.5013941829 40467.16734388865 38557.14422633259 40477.444780837825 32292.08617467376 33200.28393885522 33252.45221348973 34990.681391444276 37855.604650378315 0.9407968578604565 1.0073937993168942 1.068987478013622 1.0185319870712266 1.0692589685113723 0.8530331630656187 0.8770242674891054 0.8784023533793275 0.924319706807129 1.0 15.208219291456944 -6.762106910868256 24.99999992180736 0.8971103132569285 1.0227678115800722 0.5606551295671238 0.05029326055870819 12.478662139761678 467330.42551033007 0.017039676332219117 0.015928616381603537 1.7293905803589007e-07 6.762106910868256 0.12565749832314377 VGIDTPDIDIHGPEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VGIDTPDIDIHGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ; 93.23700000000001 0.0031376 3269200.0 37879.0 36586.0 37769.0 46730.0 51269.0 39221.0 39188.0 39868.0 38691.0 33157.0 False True 44291.16655564773 40218.01629154942 38669.55619973015 44111.86960070412 41223.207487595966 37164.18171537557 35475.82894344932 38821.50724363769 39256.782678819385 39168.10162933243 1.1307968656433098 1.0268053497244485 0.987271646853854 1.1262192387610988 1.0524688655506473 0.9488379617444581 0.9057326617249681 0.9911511058418215 1.0022641140570505 1.0 15.257391586053142 -6.7240623927632575 7.213274617222536 0.9650588362983228 1.0621618289865413 0.4965486179592091 0.047764996702468594 0.1791893570489062 26.633022128797137 0.01647308914016994 0.016252189026402946 1.8877201309690603e-07 6.7240623927632575 0.09710299268821854 VGIDTPDIDIHGPEGK ddPTM_PC-9_Lapatinib_30min_R1 2 VGIDTPDIDIHGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ; 95.822 0.0020226 9846000.0 110739.0 93037.0 94647.0 90171.0 98073.0 84729.0 85832.0 86372.0 101939.0 74337.0 False True 109159.84155295465 92821.57854267608 86865.48900798544 96802.47614163802 92304.53895893664 81105.33818294587 90275.96098079864 90385.15843648803 90457.55635474114 87186.05140217375 1.252033321814515 1.0646379443714757 0.9963232376161915 1.110297743558834 1.0587076427300535 0.9302558939023556 1.0354404119573175 1.0366928767029184 1.0375232608881038 1.0 16.411809721173483 -4.769072604449465 3.505880214766642 1.028034767216781 1.2824695138810553 0.7025680084000607 0.04395584440672654 0.17334380333560034 3.4640637287971137 0.011500033909548868 0.12012370629950991 1.7018739688558877e-05 4.769072604449465 0.25443474666427424 VGINYQPPTVVPGGDLAK ddPTM_PC-9_AZD4547_30min_R2 2 VGINYQPPTVVPGGDLAK 18 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;Q6PEY2;Q9NY65-2;Q9NY65;C9J2C0;V9GZ17;P68363;P68363-2;P68366-2;P68366;Q71U36-2;Q71U36 Q9BQE3;P68363;P68366-2;Q71U36-2 TUBA1C;TUBA3E;TUBA8;TUBA1B;TUBA4A;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-8 chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain;Tubulin alpha-1A chain 0 ; 203.85 1.1968999999999997e-54 3516200.0 36918.0 37654.0 46555.0 60214.0 51555.0 48988.0 44110.0 58950.0 44952.0 42105.0 False True 48657.15605789655 49824.9191358974 45937.65028150337 46332.59259702629 44397.47815407728 45924.772615831076 48035.70454760728 49840.632036237475 47328.07094867318 40630.916765764574 1.1975401967522143 1.2262809481542305 1.1306082643010955 1.1403285056089585 1.0927018558312815 1.1302913217682324 1.182245156429302 1.2266676709158817 1.1648290197712594 1.0 15.310290296382808 -10.544422975755268 3.911947487131175 0.9999759364971568 1.1648118395231901 0.5904329991366828 0.04140108149286526 32790112.534174744 52604354.29676497 10137.24620855045 0.011584583031843326 2.8548087831532327e-11 10.544422975755268 0.16483590302603335 VGINYQPPTVVPGGDLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VGINYQPPTVVPGGDLAK 18 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;Q6PEY2;Q9NY65-2;Q9NY65;C9J2C0;V9GZ17;P68363;P68363-2;P68366-2;P68366;Q71U36-2;Q71U36 Q9BQE3;P68363;P68366-2;Q71U36-2 TUBA1C;TUBA3E;TUBA8;TUBA1B;TUBA4A;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-8 chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain;Tubulin alpha-1A chain 0 ; 212.55 8.5983e-21 15964400.0 85548.0 85049.0 81916.0 97730.0 109006.0 89765.0 96644.0 93390.0 81381.0 75086.0 False True 100029.58674998168 93492.10265074015 83869.1881081598 92254.504944935 87647.05680611837 85057.56537774875 87489.18067803174 90938.61145488429 82571.04316727404 88698.49741955104 1.1277483797367351 1.054043815517133 0.9455536513933464 1.0400909556400235 0.988145902760232 0.9589515927808744 0.9863659839038859 1.0252553774923303 0.9309181730182683 1.0 16.43662204457496 -4.961112809788129 3.298554152683085 0.9866751960357372 1.126532252134381 0.6653589098564443 0.03216058673245672 0.14632082305410743 3.074475058956418 0.007948433030908579 0.041810349015886435 1.0936722434834479e-05 4.961112809788129 0.13985705609864385 VGINYQPPTVVPGGDLAK ddPTM_PC-9_Lapatinib_30min_R1 2 VGINYQPPTVVPGGDLAK 18 0 Q9BQE3;F5H5D3;A0A1W2PQM2;P0DPH8;P0DPH7;P0DPH7-2;Q6PEY2;Q9NY65-2;Q9NY65;C9J2C0;V9GZ17;P68363;P68363-2;P68366-2;P68366;Q71U36-2;Q71U36 Q9BQE3;P68363;P68366-2;Q71U36-2 TUBA1C;TUBA3E;TUBA8;TUBA1B;TUBA4A;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-8 chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain;Tubulin alpha-1A chain 0 ; 162.67 6.6804e-06 53157000.0 242874.0 262490.0 266350.0 288960.0 275030.0 242427.0 299180.0 213366.0 231436.0 283490.0 False True 239410.57222236381 261882.22053233706 244451.73114073262 310211.082342302 258853.27612978415 232058.96233493896 314670.07650101697 223279.7632908781 205369.24055087726 332490.8687733187 0.7200515704555666 0.7876373312100782 0.7352133670395373 0.9329912832998541 0.7785274738063912 0.6979408583191772 0.9464021603418789 0.6715365270470115 0.6176688139092663 1.0 18.342955194730813 -11.8890726972723 2.428770453497148 2.7754953759617074 0.7710046254079844 0.33017915251604735 0.09997926511879007 5298240.935478295 1068439.7860761373 52742217.784807324 0.025691346681808704 1.2910031523706597e-12 11.8890726972723 -2.004490750553723 VGLIAAR ddPTM_PC-9_Lapatinib_30min_R1 1 VGLIAAR 7 0 E9PKU4;P62917;E9PP36 E9PKU4 RPL8 60S ribosomal protein L8 0 90.939 0.026498 0.0 19484.0 16759.0 18422.0 16564.0 17213.0 16549.0 19120.0 13762.0 15588.0 13843.0 False True 19206.15458707201 16720.19556516989 16907.414270976442 17782.171815884198 16200.565182060069 15841.237847603197 20109.9400451215 14401.432760651021 13832.315291082949 16235.744105361951 1.1829549950056841 1.029838574485043 1.041369841828972 1.0952483422063501 0.9978332423156223 0.9757013749909703 1.2386213970002196 0.8870201862749773 0.8519668209426104 1.0 13.986885886287086 -7.814983644709437 24.99999757157909 0.9021193150851543 1.070181150393551 0.44936923513014504 0.08405991400011141 87.12558474952809 40677.935523335946 0.044486474627324385 0.021370631985777874 1.5311451226767818e-08 7.814983644709437 0.1680618353083967 VGLSPDSPAGDRNS(ph)VGSEGSVGSIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VGLSPDSPAGDRNSVGSEGSVGSIR 25 1 Q8WXE0-2;Q8WXE0 Q8WXE0-2 CASKIN2 Caskin-2 1 VGLS(0.022)PDS(0.405)PAGDRNS(0.534)VGS(0.03)EGS(0.007)VGS(0.002)IR;VGLS(0.004)PDS(0.224)PAGDRNS(0.671)VGS(0.059)EGS(0.027)VGS(0.015)IR;VGLSPDS(0.011)PAGDRNS(0.708)VGS(0.258)EGS(0.02)VGS(0.003)IR 57.768 0.0022656 48879000.0 64558.0 57257.0 71445.0 81053.0 106369.0 76662.0 77960.0 74973.0 79516.0 69554.0 True False 75486.39432137879 62941.09656166962 73148.5197566715 76511.86318737142 85526.75802625534 72641.70976426196 70575.06441847775 73005.03819045963 80678.77107050736 82163.5896108391 0.9187329165986261 0.7660460899990471 0.8902790165708836 0.9312137353025031 1.0409325886483975 0.884110712644412 0.8589579003637813 0.8885327252161428 0.981928509363278 1.0 16.326211591885077 -1.522878745282321 0.07874871609287563 1.0617167563999674 0.5217385094037492 0.2175228009639324 0.06585351539980185 353.7141652758621 2.0419453766145392 2.153591695096951 20.824130405944054 0.029999999999862994 1.522878745282321 -0.5399782469962182 VGLSPDSPAGDRNS(ph)VGSEGSVGSIR ddPTM_PC-9_Lapatinib_30min_R1 1 VGLSPDSPAGDRNSVGSEGSVGSIR 25 1 Q8WXE0-2;Q8WXE0 Q8WXE0-2 CASKIN2 Caskin-2 1 VGLSPDS(0.058)PAGDRNS(0.806)VGS(0.112)EGS(0.015)VGS(0.008)IR 48.607 0.015227000000000001 25657000.0 38774.0 32600.0 53885.0 36006.0 47467.0 35054.0 32105.0 30239.0 43122.0 28770.0 True False 38221.07564971925 32524.516702938035 49454.78330211516 38654.00135249493 44675.084383712594 33554.82213486511 33767.23980902852 31644.01433289684 38265.14626520908 33742.85616638468 1.1327160765897424 0.9638934102839707 1.4656371428149293 1.1455462205657279 1.3239864510408228 0.9944274417496736 1.0007226312592985 0.9377989277748591 1.1340221490594977 1.0 15.042294475364642 -6.78253002890623 24.994834262135832 1.008714612183773 1.2039119299818613 0.3533757939758244 0.13041367305545837 278.2693345013947 329778.77373929205 0.04606023885412631 0.04066199508667653 1.6499469132621078e-07 6.78253002890623 0.19519731779808835 VGLVEDSPSTAGDGDDSPVVSLTVPSTS(ph)PPSSSGLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VGLVEDSPSTAGDGDDSPVVSLTVPSTSPPSSSGLSR 37 0 Q6VY07-2;Q6VY07;B4DF77 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 VGLVEDSPSTAGDGDDS(0.002)PVVS(0.038)LT(0.004)VPS(0.053)T(0.125)S(0.6)PPS(0.102)S(0.035)S(0.035)GLS(0.005)R 72.25399999999999 6.6628e-07 2584800.0 7603.9 6903.5 7100.9 7329.1 9217.0 9262.9 9386.7 8637.1 8631.4 6952.8 True False 8891.09008612925 7588.833856357927 7270.212386313217 6918.474288262794 7410.995014788118 8777.13721759649 8497.523822177085 8410.385276763905 8757.617895995485 8213.287601665486 1.0825251126389779 0.9239703057298355 0.8851768912656811 0.8423513973697779 0.9023177288087806 1.0686509036669636 1.0346068753825157 1.0239974154878555 1.0662743496550176 1.0 13.003744101942996 -6.758246343169064 24.99987696076383 1.0399495642763095 0.9200290376038633 0.45156328388006484 0.06113791163538727 77.98324720885628 610569.938334043 0.021663426985291372 0.020802913972968354 1.7448321578160436e-07 6.758246343169064 -0.11992052667244613 VGLVEDSPSTAGDGDDSPVVSLTVPSTS(ph)PPSSSGLSR ddPTM_PC-9_Lapatinib_30min_R1 2 VGLVEDSPSTAGDGDDSPVVSLTVPSTSPPSSSGLSR 37 0 Q6VY07-2;Q6VY07;B4DF77 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 VGLVEDSPSTAGDGDDS(0.031)PVVS(0.077)LT(0.002)VPS(0.159)T(0.159)S(0.511)PPS(0.041)S(0.014)S(0.004)GLS(0.002)R;VGLVEDSPSTAGDGDDSPVVSLTVPS(0.046)T(0.257)S(0.641)PPS(0.032)S(0.01)S(0.01)GLS(0.004)R 96.42 5.1341e-12 2292400.0 7998.0 6695.7 8341.7 6702.700000000001 7453.7 10701.8 6936.4 6405.9 11069.599999999999 6909.0 True False 7883.947053346429 6680.1965180325815 7655.877625893181 7195.638917551735 7015.288020538024 10244.108961114263 7295.532851934137 6703.54149988769 9822.825079944309 8103.211444336174 0.97294105028655 0.8243887702944955 0.9447954898479588 0.8879984148236936 0.8657416962063151 1.2642035853913811 0.9003261116965456 0.8272697245945867 1.2122138423044702 1.0 12.984278071251994 VGMADANS(ph)PPKPLSKPR ddPTM_PC-9_Lapatinib_30min_R1 1 VGMADANSPPKPLSKPR 17 2 P26358;P26358-2;K7EJL0 P26358 DNMT1 DNA (cytosine-5)-methyltransferase 1 1 VGMADANS(0.998)PPKPLS(0.002)KPR 47.618 0.031882 31833000.0 52002.0 48436.0 47372.0 41460.0 41704.0 43249.0 39234.0 42448.0 44921.0 39835.0 True False 51260.44194400117 48323.84941789894 43477.2570212081 44509.10670650556 39251.052713218654 41399.341088343164 41265.34454656363 44420.28904404264 39861.52394089922 46720.42667319896 1.0971740969439086 1.0343195227200221 0.9305834753035057 0.9526690973487637 0.8401261612564619 0.8861079411351305 0.8832398906629716 0.950768051729378 0.8531926349843391 1.0 15.511765829206109 -5.0832361916579805 1.3578075369725864 0.9006149827725162 1.129991167349976 0.6563522954199141 0.045830575797377794 0.43809329921779805 1.055518361187523 0.013186493934216996 0.11915478058567427 8.255888298277545e-06 5.0832361916579805 0.2293761845774599 VGNES(ph)PVQELK ddPTM_PC-9_AZD4547_30min_R2 4 VGNESPVQELK 11 0 Q5JSH3-2;Q5JSH3 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 VGNES(1)PVQELK;VGNES(1)PVQELK;VGNES(1)PVQELK;VGNES(1)PVQELK 188.13 0.00078447 339802000.0 394366.0 405902.0 444326.0 424319.0 427555.0 477764.0 444350.0 503889.0 424970.0 445759.0 True False 519766.18467762193 537101.8836537689 438433.94692254864 326498.81021319964 368196.3683865092 447889.3415536436 483896.28917998885 426024.5332673052 447433.0466065495 430153.11308848 1.2083283111581458 1.2486295398338547 1.0192508983013342 0.7590292858023341 0.8559658344510768 1.0412323610488792 1.1249396423186042 0.9904020691805951 1.040171587726055 1.0 18.7144907532629 -5.321692036690834 4.931471670780137 0.9716263990457925 1.2291386029875135 0.515665752971787 0.09721406780652647 0.16975060729822697 8.54330009603989 0.02908873370488119 0.06456222272395432 4.767689494167164e-06 5.321692036690834 0.25751220394172103 VGNES(ph)PVQELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VGNESPVQELK 11 0 Q5JSH3-2;Q5JSH3 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 VGNES(1)PVQELK;VGNES(1)PVQELK;VGNES(1)PVQELK;VGNES(1)PVQELK 182.72 0.0013912 214028800.0 322418.0 334452.0 291264.0 356616.0 374288.0 309725.0 353605.0 295765.0 278053.0 267171.0 True False 376996.9993542286 367654.18424373434 298208.83838487143 336635.96168467135 300948.9532488901 293482.47576029913 320108.97452149575 288001.4821389214 282118.9991004052 315606.9873755278 1.1945141091114544 1.164911421325022 0.9448740056887428 1.0666302558254899 0.9535560532150175 0.9298985367871352 1.0142645357233844 0.9125320213403268 0.893893387616046 1.0 18.267769620664076 -4.6526390034966685 0.7394607477821546 0.9471273262035775 1.425374024622231 0.7103710779560202 0.05331171546580919 1.7377829133642024 0.6344170520134425 0.021163138108479175 0.7233613860608744 2.225158730081464e-05 4.6526390034966685 0.4782466984186535 VGNES(ph)PVQELK ddPTM_PC-9_Lapatinib_30min_R1 5 VGNESPVQELK 11 0 Q5JSH3-2;Q5JSH3 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 VGNES(1)PVQELK;VGNES(1)PVQELK;VGNES(1)PVQELK;VGNES(1)PVQELK;VGNES(1)PVQELK 206.66 5.390399999999999e-06 306328900.0 275617.0 445514.0 443283.0 417171.0 505596.0 439729.0 453505.0 462047.0 453795.0 379435.0 True False 271686.6510380329 444482.4397052978 406837.98286186316 447851.14698166 475857.83731998166 420922.8157283647 476985.26988299325 483515.390405503 402683.8284268024 445019.8341846426 0.6105045891624411 0.9987924257795624 0.9142019110390089 1.006362217095795 1.0692957948533686 0.9458518101773418 1.0718292382561265 1.086503012368856 0.9048671485948319 1.0 18.763510111734156 -4.429714999391384 1.9705797146678314 1.0080419726848977 2.957429178294869e-13 0.7698700188810789 0.06313109087999307 1.308786767051686 2.195351599109944 0.016599994503986488 3.3779725899277198 3.717791247077002e-05 4.429714999391384 -1.008041972684602 VGNES(ph)PVQELKQDVSK ddPTM_PC-9_AZD4547_30min_R2 2 VGNESPVQELKQDVSK 16 1 Q5JSH3-2;Q5JSH3 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 VGNES(1)PVQELKQDVSK;VGNES(1)PVQELKQDVSK 91.969 0.0014811 17945400.0 57027.0 36421.0 69122.0 132098.0 119467.0 81989.0 57426.0 72777.0 54036.0 92325.0 True False 75160.39976471278 48193.37599852655 68205.39711648747 101644.8469937554 102881.06920052665 76862.21486893471 62536.80275109716 61530.98689908831 56892.23264331962 89092.72985154294 0.843619899064201 0.540935001978637 0.7655551382266491 1.1408882314317712 1.1547639113983768 0.8627215149542707 0.7019293589421216 0.6906398199002171 0.6385732341810642 1.0 16.443020089242104 -13.176919260224471 14.4816495932597 0.9869332294273807 0.8298981054443052 0.0 0.19810773277086602 0.0 0.0 0.0 0.050329146949423136 6.653968487671222e-14 13.176919260224471 -0.1570351239830755 VGNES(ph)PVQELKQDVSK ddPTM_PC-9_Lapatinib_30min_R1 2 VGNESPVQELKQDVSK 16 1 Q5JSH3-2;Q5JSH3 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 VGNES(1)PVQELKQDVSK;VGNES(1)PVQELKQDVSK 65.467 0.013404 14523400.0 130149.0 50962.0 60603.0 72241.0 58020.0 62594.0 38372.0 32482.0 65788.0 33698.0 True False 128293.05139359643 50844.00062009594 55620.455274345084 77553.84412891165 54607.37767170885 59917.00053374072 40358.71440436203 33991.2323013709 58378.262661647816 39522.65440023743 3.2460636397140803 1.2864520713920091 1.4073056609783514 1.9622630439631035 1.3816728279105868 1.516016609789771 1.021153943651102 0.8600442661858942 1.4770835498664563 1.0 15.270392223270093 -4.760460378682938 24.999305686180836 1.3401383968491765 3.2460658836775877 0.7880902265331686 0.29896166377297345 11.583243883278683 295634.6781802802 0.07954406507514668 0.47053377523252615 1.7359596297684852e-05 4.760460378682938 1.9059274868284113 VGNTVPFGAGAAVGGGGGS(ph)SSSSEDVKR ddPTM_PC-9_AZD4547_30min_R2 1 VGNTVPFGAGAAVGGGGGSSSSSEDVKR 28 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 VGNTVPFGAGAAVGGGGGS(0.265)S(0.265)S(0.265)S(0.189)S(0.017)EDVKR 95.361 7.168099999999999e-10 6721500.0 17783.0 15618.0 19663.0 22591.0 23029.0 20872.0 20058.0 18392.0 19788.0 23750.0 True False 23437.624090621764 20666.213073363935 19402.255772424043 17382.993977470716 19831.820859475236 19566.870540492087 21843.123142505254 15549.939006115002 20833.953281997346 22918.519728937397 1.022649995192706 0.9017254743232979 0.8465754334005418 0.7584693157788279 0.8653185761572187 0.853758042487646 0.9530773977049519 0.6784879298500822 0.9090444552442872 1.0 14.484226245254801 -4.809927459028095 2.4421697422053428 0.8469818557653209 1.0559603974447065 0.23884426766439837 0.08671535183839096 0.6527321339419395 5.135669206077583 0.021547884711682348 0.2844077344104975 1.5490753420859845e-05 4.809927459028095 0.20897854167938557 VGNTVPFGAGAAVGGGGGSS(ph)SSSEDVKR ddPTM_PC-9_Lapatinib_30min_R1 1 VGNTVPFGAGAAVGGGGGSSSSSEDVKR 28 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 VGNTVPFGAGAAVGGGGGS(0.265)S(0.612)S(0.086)S(0.029)S(0.008)EDVKR 68.694 9.123e-05 5531700.0 15441.0 13309.0 16396.0 17530.0 12561.0 15906.0 13397.0 10955.0 17708.0 10936.0 True False 15220.808508467408 13278.18382820252 15047.984170390284 18819.21467836572 11822.18667587617 15225.737458696993 14090.631107975552 11464.009293193725 15713.538566493253 12826.273028695976 1.1866898883576065 1.0352332122118009 1.1732156439149328 1.4672395197156531 0.9217164369904349 1.1870741738175026 1.098575640519335 0.8937911478685597 1.2251055728610838 1.0 13.646814402344054 -6.318078377504442 24.999969869359305 1.0579115972015154 1.1996883825523565 0.23949455040219203 0.13950911523854784 480.05971694818294 211892.8122562801 0.04338630134363325 0.04919546033002694 4.807525787825053e-07 6.318078377504442 0.14177678535084115 VGNTVPFGAGAAVGGGGGSSS(ph)SSEDVKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VGNTVPFGAGAAVGGGGGSSSSSEDVKR 28 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 VGNTVPFGAGAAVGGGGGS(0.221)S(0.221)S(0.263)S(0.263)S(0.034)EDVKR 43.795 0.018602 8206600.0 15348.0 14711.0 17421.0 21759.0 21582.0 20288.0 20201.0 19253.0 24366.0 19915.0 True False 17946.11326318228 16171.410858387995 17836.382709510406 20539.913773629793 17353.162027683305 19224.06156501719 18287.415037425224 18747.629150239714 24722.30665405682 23525.43185294675 0.7628388450150548 0.6874012328221042 0.7581745075288068 0.873094015957756 0.7376341542274253 0.8171608362041278 0.777346624356848 0.7969090330595323 1.0508757844953291 1.0 14.521933586090347 -8.229939663148835 6.026584662039307 1.0263563862850729 0.7752929020283031 0.8149281904519367 0.047509731124458665 0.06881187128305981 8.205017107905277 0.036240130661774964 0.012609322895901153 5.889254695199876e-09 8.229939663148835 -0.2510634842567697 VGNTVPFGAGAAVGGGGGSSS(ph)SSEDVKR ddPTM_PC-9_Lapatinib_30min_R1 1 VGNTVPFGAGAAVGGGGGSSSSSEDVKR 28 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 VGNTVPFGAGAAVGGGGGS(0.169)S(0.169)S(0.376)S(0.213)S(0.074)EDVKR 60.196999999999996 0.0007436 5982200.0 17896.0 17472.0 24465.0 19597.0 19366.0 19197.0 13512.0 17173.0 18486.0 16084.0 True False 17640.799758275527 17431.54465747648 22453.582137631023 21038.228753675598 18226.929955020925 18375.989060392698 14211.585245276236 17970.92027311873 16403.912013790057 18864.09796941715 0.9351520431496455 0.9240592731089949 1.1902812514032324 1.115252305611601 0.966223245053688 0.9741249801704919 0.753366806529331 0.9526519795568036 0.8695836949312077 1.0 14.203355495538354 -6.775350185610762 2.4875125254886417 0.8900384374122676 1.0405464717046484 0.28808686676382866 0.09662877678741563 0.3560653388466427 4.517176484845913 0.03848758387191343 0.03531392259811416 1.6774508900491155e-07 6.775350185610762 0.1505080342923808 VGPAT(ph)PSAQVGK ddPTM_PC-9_AZD4547_30min_R2 2 VGPATPSAQVGK 12 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 VGPAT(0.5)PS(0.5)AQVGK;VGPAT(0.5)PS(0.5)AQVGK 115.24 0.0017894000000000002 133506000.0 260099.0 312145.0 304291.0 300412.0 299072.0 370124.0 336801.0 399690.0 350661.0 298237.0 True False 342805.0716047137 413039.766921833 300255.9025197928 231156.65471913276 257551.01515849505 346980.08776969597 366775.63653000916 337927.0944624889 369196.2245713798 287795.8134062781 1.1911398833338123 1.4351833754396885 1.0432948935776385 0.8031967247307087 0.8949088317518824 1.2056467523378045 1.2744300627203222 1.1741904458680956 1.2828408453954459 1.0 18.134686079642428 VGPAT(ph)PSAQVGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VGPATPSAQVGK 12 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 VGPAT(0.672)PS(0.328)AQVGK;VGPAT(0.649)PS(0.351)AQVGK;VGPAT(0.679)PS(0.321)AQVGK 115.34 0.001778 174419000.0 439560.0 529290.0 495800.0 415800.0 526150.0 346740.0 498690.0 331094.0 351170.0 295492.0 True False 513968.8262942657 581834.4132442503 507621.75233197125 392504.074041788 423054.68449937884 328556.3439991153 451450.4729970599 322403.13332309085 356305.1969016305 349062.36048661487 1.4724269485193444 1.6668494776496 1.454243739211282 1.1244525863361854 1.2119745134067563 0.9412540026976471 1.2933232685635585 0.9236261763475174 1.0207494053638972 1.0 18.413125273415943 -5.72636859542077 2.474868549496055 1.0698914847248986 1.576282352335718 0.7687321107842549 0.11637873596756713 0.12608081468706653 1.571042105473499 0.033241011438262184 0.06284515242588956 1.8777224753445151e-06 5.72636859542077 0.5063908676108193 VGPAT(ph)PSAQVGK ddPTM_PC-9_Lapatinib_30min_R1 2 VGPATPSAQVGK 12 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 VGPAT(0.952)PS(0.048)AQVGK;VGPAT(0.69)PS(0.31)AQVGK 111.72 0.0025421 133858000.0 161379.0 213782.0 225450.0 188550.0 242068.0 217009.0 209729.0 193287.0 223418.0 170915.0 True False 159077.70586671578 213287.00091372713 206914.3712621669 202416.59598436128 227830.03616399906 207728.03094268698 220587.74140812154 202267.81964888476 198254.3121441601 200457.4300200776 0.7935735076059927 1.064001473491726 1.0322110347391094 1.0097734764138573 1.136550718729557 1.0362700495655421 1.1004218770340801 1.009031292223121 0.9890095474350996 1.0 17.612936366879154 -4.7588824967644685 24.990622395380065 1.0455021006571683 0.7935731736896687 0.7368843102443873 0.044473200541406126 34.6596673309287 338689.41037488036 0.011039369508487407 0.07310811192941924 1.7422782025056677e-05 4.7588824967644685 -0.2519289269674996 VGPATPS(ph)AQVGK ddPTM_PC-9_AZD4547_30min_R2 2 VGPATPSAQVGK 12 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 VGPAT(0.324)PS(0.676)AQVGK;VGPAT(0.351)PS(0.649)AQVGK 109.15 0.0013474000000000001 145865000.0 104983.0 117232.0 126280.0 106690.0 126595.0 124930.0 125073.0 168755.0 132905.0 114385.0 True False 138365.41021794657 155124.95140329117 124605.44469011363 82094.26884406846 109019.46943876255 117118.10735069386 136204.25470149363 142677.79235411796 139930.08696906504 110380.41596608429 1.2535322412669745 1.405366613684036 1.1288727588089553 0.7437394407835255 0.9876703986353892 1.061040641364133 1.2339530840628834 1.292600604059668 1.2677075525069614 1.0 16.752124701852715 -5.35722131717435 6.040699416317778 1.0862294170625701 1.327611878080217 0.27579151622456344 0.15642108521150472 0.31669714653258285 16.239021932841254 0.04673280026002084 0.0991422801144883 4.393176813791175e-06 5.35722131717435 0.24138246101764693 VGPCS(ph)SPPAAR ddPTM_PC-9_AZD4547_30min_R2 1 VGPCSSPPAAR 11 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;A0A0J9YYG8 Q8TDM6-4 DLG5 Disks large homolog 5 1 VGPCS(0.5)S(0.5)PPAAR 79.036 0.017726 47424000.0 75814.0 86119.0 128290.0 150240.0 160110.0 124860.0 106490.0 144500.0 109740.0 123600.0 True False 99921.27497083736 113955.28260116705 126588.79077680303 115604.48918486128 137881.49019977322 117052.48446175939 115967.4037015348 122170.845279666 115540.63236134972 119272.80162091179 0.8377540697704079 0.9554171701554763 1.061338285480573 0.969244350881355 1.156017871014768 0.9813845476170728 0.9722870774019157 1.0242976069931278 0.968708966261863 1.0 16.86390556994086 -4.8548100760450845 2.9620879974254404 1.0179071050045725 0.8220237488546313 0.4992614633975504 0.05458581162929851 0.268701195651225 3.7519332855035787 0.013866773213289113 0.11634244432252723 1.3969791489201627e-05 4.8548100760450845 -0.19588335614994123 VGPCS(ph)SPPAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VGPCSSPPAAR 11 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;A0A0J9YYG8 Q8TDM6-4 DLG5 Disks large homolog 5 1 VGPCS(0.5)S(0.5)PPAAR 75.566 0.021583 11144000.0 20339.0 22097.0 27210.0 32854.0 37249.0 31692.0 26034.0 29169.0 29521.0 23793.0 True False 23781.990986438894 24290.644126014507 27858.789594499634 31013.296894105126 29950.32584418385 30030.01572942256 23567.87105016228 28403.344657110185 29952.68877675496 28106.482554715643 0.8461389980102225 0.8642363582396787 0.9911873369521135 1.1034214912424816 1.0656020647862552 1.0684373496741304 0.8385208289326874 1.010562051007864 1.0656861355185678 1.0 14.778615295438074 -5.285450184549666 3.912069130618732 1.020018284150353 0.8506501116652448 0.4781572776378604 0.06861915585368629 0.19272751381291187 6.688032395895847 0.01965262820637281 0.049356040551688504 5.182625355462162e-06 5.285450184549666 -0.16936817248510805 VGPCS(ph)SPPAAR ddPTM_PC-9_Lapatinib_30min_R1 1 VGPCSSPPAAR 11 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;A0A0J9YYG8 Q8TDM6-4 DLG5 Disks large homolog 5 1 VGPCS(0.626)S(0.374)PPAAR 115.91 0.0013124 33863000.0 55923.0 50106.0 52066.0 45441.0 60188.0 54573.0 51879.0 44451.0 56448.0 48807.0 True False 55125.52776497778 49989.9826355035 47785.334460572114 48782.88272673227 56647.86017416089 52239.040005876464 54565.04077410346 46516.35573635363 50090.23181620805 57243.22491876041 0.9630052786720512 0.8732908166241382 0.8347771204083814 0.8522036065571942 0.9895993849849574 0.9125803111200341 0.9532139541673651 0.8126089297444309 0.8750421012669378 1.0 15.804817331195514 -4.749099781786706 24.489048376180847 0.8957791257436023 0.9630054807807951 0.0834120049065854 0.06059568751225019 1171.546395884977 2324854.108048492 0.01529519966341035 0.25462724344593324 1.7819693021750043e-05 4.749099781786706 0.06722635503719276 VGPCSS(ph)PPAAR ddPTM_PC-9_AZD4547_30min_R2 1 VGPCSSPPAAR 11 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;A0A0J9YYG8 Q8TDM6-4 DLG5 Disks large homolog 5 1 VGPCS(0.318)S(0.682)PPAAR 96.756 0.0056731 14734000.0 21340.0 21159.0 33393.0 47986.0 34321.0 37527.0 27739.0 36499.0 23210.0 35660.0 True False 28125.676100425593 27998.2329632032 32950.18700140139 36923.56907630957 29556.121573583303 35180.430757620095 30207.717262436607 30858.91821358152 24436.83321584589 34411.55425405926 0.8173323382249679 0.8136288397929736 0.9575326577268598 1.0729991677709236 0.8589010933761239 1.022343556407951 0.8778364685132827 0.8967603725699586 0.7101345389815769 1.0 15.070605434774123 -10.101158904110543 10.418975615486218 0.9999930800252065 0.8994826251838802 0.09033750599754553 0.1003332809402516 0.0 0.0 0.09977323108971421 0.02419856296423833 7.922114150233641e-11 10.101158904110543 -0.10051045484132626 VGPCSS(ph)PPAAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VGPCSSPPAAR 11 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;A0A0J9YYG8 Q8TDM6-4 DLG5 Disks large homolog 5 1 VGPCS(0.05)S(0.95)PPAAR;VGPCS(0.316)S(0.684)PPAAR 108.31 0.0022008 49315000.0 101806.0 108889.0 145636.0 146277.0 161588.0 151994.0 165026.0 130006.0 134331.0 124127.0 True False 119039.7450398446 119698.78029766912 149108.51456760554 138081.57392643226 129925.99136916349 144023.16706985512 149393.5425952247 126593.48025274335 136295.33674571538 146630.2425112084 0.8118362419726968 0.8163307803880864 1.0169015069057648 0.941699144471355 0.886079086715225 0.9822200700435042 1.018845362571129 0.8633517757639019 0.9295172292666499 1.0 17.161823164683526 -5.241149272392293 23.83454472952733 0.9502870663679371 0.8140834253477026 0.5594863572997097 0.04982415773666694 341.03751223585 400609.3706796171 0.012936254166813129 0.034116513224368906 5.739191651773274e-06 5.241149272392293 -0.13620364102023452 VGPCSS(ph)PPAAR ddPTM_PC-9_Lapatinib_30min_R1 1 VGPCSSPPAAR 11 0 Q8TDM6-4;Q8TDM6;Q8TDM6-2;A0A0A0MSL1;A0A0J9YYG8 Q8TDM6-4 DLG5 Disks large homolog 5 1 VGPCS(0.17)S(0.83)PPAAR 77.288 0.019669 14081000.0 25490.0 20695.0 29294.0 25265.0 24787.0 27683.0 15330.0 20469.0 24237.0 17455.0 True False 25126.507925706504 20647.081998997008 26885.560398110094 27123.072381569313 23329.077393116986 26499.062622224865 16123.71238973391 21420.064465758307 21507.173833075292 20472.07349267449 1.2273553010982257 1.0085486458606716 1.3132797910153329 1.324881546135263 1.139556156901489 1.2944005223362942 0.7875954722174794 1.0463065440549064 1.0505615779843303 1.0 14.32136961117811 -7.2446934346618495 24.99821137292895 0.9749747623535822 1.2141060054276507 0.5428240850008609 0.11094134098889101 665.2503585022108 993081.7777153142 0.043075273703415976 0.03327453529963757 5.692546217779564e-08 7.2446934346618495 0.23913124307406852 VGQQAIVLCIS(ph)PSKPNPVFK ddPTM_PC-9_Lapatinib_30min_R1 1 VGQQAIVLCISPSKPNPVFK 20 1 C9JP85;Q16656-2;Q16656;Q16656-4 C9JP85 NRF1 Nuclear respiratory factor 1 1 VGQQAIVLCIS(0.663)PS(0.337)KPNPVFK 59.428999999999995 0.007274500000000001 19488000.0 32680.0 34971.0 35031.0 34833.0 38436.0 33542.0 32326.0 28962.0 31896.0 28560.0 True False 32213.977207222 34890.02679811184 32150.886403570512 37394.73501948166 36175.27004808345 32107.486850220957 33999.682107667235 30307.680250979134 28303.536600229774 33496.557946192115 0.9617100735833689 1.0416003594804621 0.9598265724859476 1.1163754520554459 1.079969772004465 0.9585309303062565 1.0150201749768835 0.9047998394242328 0.8449685082776488 1.0 15.031725233654456 -7.749890975113996 6.116927685460039 0.9054497574184845 1.0217574219771266 0.37020236014915 0.06065632487839806 0.1490678723115879 20.66064275646317 0.030939291052562806 0.01644171162245678 1.7787258836999834e-08 7.749890975113996 0.11630766455864205 VGQQAIVLCISPS(ph)KPNPVFK ddPTM_PC-9_AZD4547_30min_R2 2 VGQQAIVLCISPSKPNPVFK 20 1 C9JP85;Q16656-2;Q16656;Q16656-4 C9JP85 NRF1 Nuclear respiratory factor 1 1 VGQQAIVLCIS(0.492)PS(0.508)KPNPVFK;VGQQAIVLCIS(0.154)PS(0.846)KPNPVFK 83.602 0.00040715 49241000.0 127970.0 102241.0 146708.0 197949.0 170799.0 167581.0 137540.0 161353.0 140753.0 163916.0 True False 168661.79805864405 135288.4038182738 144762.55606269583 152314.91633156326 147086.5070553434 157102.13357829655 149780.79354971435 136419.60137307915 148192.91622705528 158177.3507321473 1.0662828608392285 0.8552956740776817 0.9151914315965017 0.9629375863646161 0.9298834907433442 0.9932024581972454 0.9469168174611079 0.8624471249622074 0.9368782290329332 1.0 17.271183510873804 -7.568332469092905 24.999879744349148 0.9207340164049904 0.948825605024043 0.006825882710018494 0.060119599833987514 483.8937767348767 266139.55923739873 0.027302808528652973 0.015763299122902148 2.7018891723346675e-08 7.568332469092905 0.028091588619052588 VGQQAIVLCISPS(ph)KPNPVFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VGQQAIVLCISPSKPNPVFK 20 1 C9JP85;Q16656-2;Q16656;Q16656-4 C9JP85 NRF1 Nuclear respiratory factor 1 1 VGQQAIVLCIS(0.138)PS(0.862)KPNPVFK;VGQQAIVLCIS(0.422)PS(0.578)KPNPVFK 75.868 0.0010635 25577000.0 174742.0 179602.0 165327.0 206868.0 211811.0 203522.0 191978.0 192827.0 177617.0 148166.0 True False 204322.36928818095 197431.6996117332 169269.02268613892 195277.85663510472 170308.15504798567 192848.9480399954 173792.45403964273 187765.49556709456 180214.3126066491 175027.32291858963 1.1673741326845142 1.128005024127373 0.9671005638637971 1.1156992712842566 0.9730375361291506 1.1018219602758543 0.9929447079555614 1.0727781950617494 1.0296353140844878 1.0 17.417220628278628 -5.077200693841018 6.104754068035606 1.0364261821281024 1.1584777667805097 0.4777592182119236 0.04907380680433444 0.1561725290160912 9.684851087025999 0.011249135792175045 0.031377868499100244 8.371423369920622e-06 5.077200693841018 0.12205158465240729 VGQQAIVLCISPS(ph)KPNPVFK ddPTM_PC-9_Lapatinib_30min_R1 1 VGQQAIVLCISPSKPNPVFK 20 1 C9JP85;Q16656-2;Q16656;Q16656-4 C9JP85 NRF1 Nuclear respiratory factor 1 1 VGQQAIVLCIS(0.167)PS(0.833)KPNPVFK 80.002 0.00071267 15117000.0 45155.0 43649.0 49289.0 51403.0 48796.0 41684.0 39974.0 44080.0 45718.0 40717.0 True False 44511.081419587186 43547.93342228658 45236.64868104211 55183.348095381254 45925.91521662714 39901.27249014995 42043.65812571582 46128.11772195154 40568.75740811716 47754.879198007846 0.9320740030569279 0.9119054252387939 0.9472675764391676 1.1555541344073443 0.961701002869315 0.8355433656256529 0.880405496397313 0.9659351776535502 0.8495206791311397 1.0 15.543360522858126 -6.536998298023701 24.522958370177562 0.9020999284870699 0.9885519700091457 0.19596110637160946 0.07744865563090964 307.9407185608795 534829.5092689581 0.026584409604374783 0.026597143710479495 2.90403403519255e-07 6.536998298023701 0.08645204152207586 VGRPS(ph)NIGQAQPIIDQLAEEAR ddPTM_PC-9_Lapatinib_30min_R1 1 VGRPSNIGQAQPIIDQLAEEAR 22 1 A0A0J9YYL3;A0A0J9YXJ8;A0A0J9YVP6;A0A0J9YXX5;Q9UHX1-4;Q9UHX1-6;Q9UHX1-3;Q9UHX1-5;Q9UHX1-2;Q9UHX1;E9PMU7;E9PN18;A0A0J9YVR6;E9PQ56;A0A0J9YWM1;H0YEM1 A0A0J9YYL3 PUF60 Poly(U)-binding-splicing factor PUF60 1 VGRPS(1)NIGQAQPIIDQLAEEAR 44.963 0.03215 908860.0 3224.3 2916.6 4349.1 3287.9 3297.9 2646.8 2875.8 2986.0 4267.0 2612.1 True False 3178.320890735796 2909.84679189537 3991.5337860114896 3529.703134112871 3103.924005920867 2533.6025339921525 3024.6948526025303 3124.740460928932 3786.405526498008 3063.598004595534 1.0374471082590382 0.9498135158498178 1.3028908427358976 1.152143045144356 1.01316295456024 0.8270022797350159 0.9873014827876742 1.0199577282142376 1.2359341926774434 1.0 11.581011288574812 -6.313051338564959 8.46862782855659 1.004008003141951 1.1127607649819742 0.1230266693331058 0.12476706279070328 0.7901263776695848 122.56604842045004 0.041359968750990954 0.04702220854557223 4.863497102060952e-07 6.313051338564959 0.10875276184002325 VGS(ph)AQPSPPDDLDAGGLAQR ddPTM_PC-9_AZD4547_30min_R2 2 VGSAQPSPPDDLDAGGLAQR 20 0 Q8N3D4;E9PIH6;H0YDZ9;A0A0U1RQH4 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 VGS(0.899)AQPS(0.101)PPDDLDAGGLAQR;VGS(0.932)AQPS(0.068)PPDDLDAGGLAQR 139.78 1.7094e-05 10107800.0 18866.6 20383.0 27309.0 35370.0 32916.0 26226.0 22047.5 30362.0 26094.6 21264.3 True False 24865.786350341594 26971.40613871026 26946.86481661638 27215.9929610526 28346.181571517962 24586.084074115828 24009.68478833307 25670.250549351003 27473.907282818265 20519.84332934919 1.211792212603128 1.3144060461774338 1.3132100661838255 1.3263255729699466 1.381403411154455 1.1981613933158428 1.1700715450391581 1.2509964202619068 1.3388945929973448 1.0 14.324732095444034 -6.7855785863695175 24.841308408781597 1.2059649370972088 1.310852984282785 0.3000324434915598 0.08860976612498073 307.99168633857346 316947.23938342516 0.030490362565170633 0.02690308562010439 1.6384055620189715e-07 6.7855785863695175 0.1048880471855762 VGS(ph)AQPSPPDDLDAGGLAQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VGSAQPSPPDDLDAGGLAQR 20 0 Q8N3D4;E9PIH6;H0YDZ9;A0A0U1RQH4 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 VGS(0.791)AQPS(0.209)PPDDLDAGGLAQR;VGS(0.87)AQPS(0.13)PPDDLDAGGLAQR;VGS(0.915)AQPS(0.085)PPDDLDAGGLAQR 211.11 1.0799e-21 11499900.0 41343.2 39111.899999999994 38843.6 45279.3 58202.0 46315.100000000006 45595.7 47711.4 45380.7 30857.8 True False 48341.78719457894 42994.670950457825 39769.778739173315 42742.44761847127 46797.73590655287 43886.25462292626 41276.545211718694 46459.02630440694 46044.30688565036 36452.07486978958 1.326173814995733 1.1794848744286586 1.0910155013462168 1.1725655609770231 1.2838154226808491 1.2039439395340952 1.1323510488542174 1.2745235071079817 1.2631463929042497 1.0 15.153713315340655 -10.698544896767832 5.519706150029765 0.9999941000978176 1.2093752953946042 0.45825459848474914 0.06966958876759737 5.255124470779913e-06 7.847977077571055e-07 0.0700813701564883 0.016996750062067162 2.00195865115173e-11 10.698544896767832 0.20938119529678656 VGS(ph)AQPSPPDDLDAGGLAQR ddPTM_PC-9_Lapatinib_30min_R1 2 VGSAQPSPPDDLDAGGLAQR 20 0 Q8N3D4;E9PIH6;H0YDZ9;A0A0U1RQH4 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 VGS(0.619)AQPS(0.381)PPDDLDAGGLAQR;VGS(0.854)AQPS(0.146)PPDDLDAGGLAQR 143.76 0.00022336 8420800.0 54322.0 54064.0 47945.0 44744.0 50135.0 45807.0 36873.4 40898.0 48487.0 31156.7 True False 53547.35831856525 53938.818129682266 44003.147173052064 48034.623021608415 47186.157869202405 43847.941391332395 38782.52422906815 42798.27038548941 43025.8834692545 36542.09408130683 1.4653609669829375 1.4760735389074147 1.2041769438594365 1.3145011042533714 1.2912822610606918 1.1999296289306771 1.0613109402755168 1.1712046466265036 1.1774334380925493 1.0 15.157271690968347 -1.5228787452803445 0.1849588952427586 1.0067766445049973 3.1462594130841546 0.7948867542964096 0.06650219945216501 25.059119651251336 0.2876628991717311 0.14820298226872827 15.182355071365938 0.02999999999999952 1.5228787452803445 2.1394827685791573 VGS(ph)GQGGSPCWK ddPTM_PC-9_AZD4547_30min_R2 1 VGSGQGGSPCWK 12 0 A0A669KBI7;Q9UMN6;Q9UMN6-2 A0A669KBI7 KMT2B Histone-lysine N-methyltransferase 2B 1 VGS(0.993)GQGGS(0.007)PCWK 143.55 8.5614e-05 12831000.0 23721.0 21684.0 34380.0 41600.0 32086.0 35360.0 28403.0 39394.0 28430.0 32565.0 True False 31263.784572549 28692.928946268625 33924.09873650706 32009.762713593074 27631.41274467508 33148.93361018591 30930.811976098154 33306.562484063405 29932.751759004685 31424.909262014553 0.9948727078852598 0.9130632234140367 1.079528932085524 1.0186111420943855 0.8792837718094882 1.0548617128468627 0.9842768906093979 1.059877761503144 0.9525167283517493 1.0 14.939620958485428 VGS(ph)LDNVGHLPAGGAVK ddPTM_PC-9_AZD4547_30min_R2 4 VGSLDNVGHLPAGGAVK 17 0 E7EVA0;P27816-4;H7C4C5;H0Y2V1;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 VGS(1)LDNVGHLPAGGAVK;VGS(1)LDNVGHLPAGGAVK;VGS(1)LDNVGHLPAGGAVK;VGS(1)LDNVGHLPAGGAVK 122.3 3.4103e-05 328117000.0 550918.0 535870.0 511040.0 663099.0 735088.0 731686.0 743318.0 569803.0 624089.0 690124.0 True False 726098.4641937335 709079.4979910064 504263.2756923963 510231.77032742463 633033.7197424942 685933.5587528977 809471.8620022307 481753.03912034264 657077.0704370541 665962.9688173983 1.0902985574154709 1.0647431331657575 0.7571941673992105 0.7661563693751358 0.9505539337519335 1.029987538152403 1.2154908003964127 0.7233931339693386 0.9866570683410167 1.0 19.345082432230612 -6.521908321017672 24.67929976736621 0.9881117351584157 0.9108640264126537 0.04712113386967265 0.14970119200747156 113.68119012614089 2891197.6853497378 0.05257386247738044 0.05325154664525105 3.0067109482857774e-07 6.521908321017672 -0.07724770874576192 VGS(ph)LDNVGHLPAGGAVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VGSLDNVGHLPAGGAVK 17 0 E7EVA0;P27816-4;H7C4C5;H0Y2V1;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 VGS(1)LDNVGHLPAGGAVK;VGS(1)LDNVGHLPAGGAVK;VGS(1)LDNVGHLPAGGAVK;VGS(1)LDNVGHLPAGGAVK 112.82 0.00013297 292652000.0 652295.0 638870.0 520091.0 781456.0 775929.0 667293.0 846886.0 740342.0 645289.0 650366.0 True False 762715.6600864917 702292.7914552605 532491.9418961001 737673.5538345362 623891.2825029321 632298.9803778102 766662.8271563249 720908.8069571897 654725.1308581503 768272.2075055785 0.9927674756879105 0.9141197411467745 0.6931032213504008 0.9601721195012509 0.8120706130039228 0.8230142574475714 0.9979051951462894 0.9383507563000775 0.8522046280756502 1.0 19.551258039079798 -7.253957436582923 24.901075081052138 0.9419777082817542 0.8620549092038787 0.16969827030245976 0.08749721109619653 1056.282846233973 3515483.1355147925 0.034097307141360306 0.025884033338632036 5.57240359092979e-08 7.253957436582923 -0.07992279907787547 VGS(ph)LDNVGHLPAGGAVK ddPTM_PC-9_Lapatinib_30min_R1 4 VGSLDNVGHLPAGGAVK 17 0 E7EVA0;P27816-4;H7C4C5;H0Y2V1;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 VGS(1)LDNVGHLPAGGAVK;VGS(1)LDNVGHLPAGGAVK;VGS(1)LDNVGHLPAGGAVK;VGS(1)LDNVGHLPAGGAVK 115.38 8.7296e-05 472701000.0 1045970.0 981750.0 688480.0 829890.0 819970.0 723540.0 776350.0 755400.0 714130.0 667280.0 True False 1031054.2759925951 979476.818193539 631875.8320096562 890922.8790318823 771740.976723045 692595.8808541191 816545.6042902756 790498.6417232787 633697.1592777184 782618.4589052899 1.3174418061066588 1.2515380988631555 0.8073868240898774 1.138387254854794 0.9861011683810013 0.8849725852657597 1.0433508116233832 1.010068996876219 0.8097140465663442 1.0 19.5779496126043 -5.13672399935544 6.040049119035419 0.968523147744487 1.30003301303333 0.6369094465668227 0.09822210084965777 0.1336012988205104 5.918500538899937 0.02418096890655852 0.06651020147285129 7.299212387597793e-06 5.13672399935544 0.33150986528884296 VGS(ph)LTPPS(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 2 VGSLTPPSSPK 11 0 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 2 VGS(0.941)LT(0.059)PPS(0.629)S(0.371)PK;VGS(0.999)LT(0.001)PPS(0.717)S(0.283)PK 124.6 0.006097999999999999 31327000.0 237877.0 229714.0 200320.0 248785.0 234185.0 241278.0 242038.0 216746.0 225527.0 232467.0 True False 313516.93785102875 303964.5581978951 197663.62591323708 191431.46193993406 201672.45507734592 226190.84851805528 263578.9131102645 183252.88602758857 237447.89679750428 224328.40108744745 1.397580227609316 1.3549981042275783 0.8811350901403878 0.8533536592422395 0.8990054495985561 1.0083023256153902 1.1749689822267153 0.8168956099150064 1.0584834360984128 1.0 17.775252758767124 -5.252618646451422 23.600626520149248 0.9581771305266278 1.376289345744489 0.7283777107673852 0.10129835519262043 150.23053755337793 401949.1212037875 0.026636781514459428 0.06802246340115095 5.5896080222363666e-06 5.252618646451422 0.4181122152178611 VGS(ph)LTPPSS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VGSLTPPSSPK 11 0 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 2 VGS(0.994)LT(0.006)PPS(0.311)S(0.689)PK 94.54700000000001 0.039658 0.0 55043.0 68338.0 40321.0 65629.0 72859.0 47071.0 65316.0 62684.0 48771.0 59593.0 True False 64360.69275119508 75122.14500989193 41282.40555824402 61952.019902088825 58582.80197270778 44602.51389624036 59128.79563311054 61038.61141918797 49484.18360933292 70396.73916207167 0.9142567328725265 1.0671253513169288 0.5864249686793184 0.8800410450753849 0.8321806190175213 0.6335877830016207 0.8399365700303336 0.8670658917689519 0.7029328943121558 1.0 16.103220983075907 -5.236149306292859 24.999211861835615 0.788547162396328 0.9906910555229953 0.29748318887667724 0.12152095229140021 885.1853470951532 875001.7559522039 0.02904608973481615 0.07678579892454751 5.805647905811046e-06 5.236149306292859 0.20214389312666725 VGS(ph)LTPPSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 VGSLTPPSSPK 11 0 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 2 VGS(0.878)LT(0.122)PPS(0.238)S(0.762)PK;VGS(0.938)LT(0.062)PPS(0.288)S(0.712)PK 127.56 0.0042912 38840000.0 375030.0 388840.0 278210.0 330920.0 335910.0 284250.0 296110.0 297030.0 285410.0 261070.0 True False 369682.00342792104 387939.664870258 255336.6477216561 355256.96071675926 316152.4342244695 272093.2901191136 311441.1269226429 310831.09816132684 253264.1202994604 306195.6016460915 1.2073393655576043 1.266966810707648 0.8339004425569135 1.160228817157779 1.032517882441324 0.8886257302729181 1.0171312887851809 1.0151390042519068 0.8271318037813926 1.0 18.22409403379657 -4.036869687861326 0.5888777496189088 0.9590947231495139 1.8181170528286943 0.3956238120850538 0.11136113873545243 8.219208172997892 1.130357082905237 0.052807787327957545 5.833049577080965 9.1860818792028e-05 4.036869687861326 0.8590223296791804 VGS(ph)PLTLTDAQTR ddPTM_PC-9_AZD4547_30min_R2 1 VGSPLTLTDAQTR 13 0 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 VGS(0.979)PLT(0.007)LT(0.014)DAQTR 99.669 0.0024486 9190100.0 22841.0 26245.0 23272.0 22225.0 28797.0 20776.0 23182.0 20397.0 20757.0 20524.0 True False 30103.96287768609 34728.183001052406 22963.398074345336 17101.369622827075 24799.033622402556 19476.87343566807 25245.153090515363 17245.112326431466 21854.17264374463 19805.461007019414 1.5199829414229087 1.753465015974337 1.1594477940304793 0.8634673849180304 1.2521310972571318 0.9834092439840261 1.2746561709201327 0.8707251156799373 1.1034417545746154 1.0 14.273610662453182 -5.351334438049333 4.9794718767149275 1.0570593945980007 1.6342762350968232 0.7276045307745858 0.14118277705744606 0.09581793332743455 3.9057399662887162 0.03489787692797654 0.07594439618357776 4.453131930747755e-06 5.351334438049333 0.5772168404988225 VGS(ph)PLTLTDAQTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VGSPLTLTDAQTR 13 0 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 VGS(0.993)PLT(0.007)LTDAQTR 120.21 0.00021615 12807000.0 44878.0 42027.0 20754.0 31972.0 39483.0 34275.0 33422.0 29939.0 26069.0 24092.0 True False 52474.95901909656 46199.16281323311 21248.854069983292 30180.71249462255 31746.589581087017 32477.55866231091 30256.026205674258 29153.13297299261 26450.20980729737 28459.688887832934 1.8438345979787087 1.6233193200149192 0.7466298789748045 1.060472326790803 1.1154932053617528 1.1411775719092871 1.063118656177907 1.0243658350550746 0.9293920924977275 1.0 14.79663227042179 -5.1158722201235385 4.952046526005294 1.024777447175089 1.7942479991717957 0.8781825084687344 0.10879803094272435 0.06672114015131285 2.3812831163411152 0.028860551127008922 0.08334858278254549 7.658218969782273e-06 5.1158722201235385 0.7694705519967067 VGS(ph)PLTLTDAQTR ddPTM_PC-9_Lapatinib_30min_R1 4 VGSPLTLTDAQTR 13 0 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 VGS(0.965)PLT(0.034)LT(0.001)DAQTR;VGS(0.998)PLT(0.002)LTDAQTR;VGS(1)PLTLTDAQTR;VGS(1)PLTLTDAQTR 137.39 5.4000000000000005e-05 50757000.0 251244.0 243621.0 144060.0 133682.0 180183.0 139864.0 133699.0 124713.0 144040.0 131462.0 True False 247661.2144874928 243056.91054252963 132215.94288768116 143513.4202300789 169584.99019340792 133882.34275890817 140621.28002576888 130507.62126719 127816.69839155675 154185.03153789596 1.6062597777309016 1.5763975797014416 0.8575147766868978 0.9307869823589576 1.0998797256900188 0.8683225694707093 0.912029388476706 0.8464350914317744 0.828982535572149 1.0 17.234303187976117 -5.25756196995584 24.999999996722845 0.917475241304892 1.5913287691791174 0.9240494338137274 0.07721617883710412 78.9154760695554 508810.4204448095 0.020833167954693286 0.05096268198706531 5.5263454628875e-06 5.25756196995584 0.6738535278742254 VGS(ph)PQPSSSGGEK ddPTM_PC-9_AZD4547_30min_R2 3 VGSPQPSSSGGEK 13 0 V9GYB6;O94761 V9GYB6 RECQL4 ATP-dependent DNA helicase Q4 1 VGS(0.774)PQPS(0.101)S(0.065)S(0.061)GGEK;VGS(0.857)PQPS(0.044)S(0.076)S(0.023)GGEK;VGS(0.684)PQPS(0.107)S(0.174)S(0.035)GGEK 95.57 0.0034825000000000004 25292100.0 77738.0 78294.0 90354.0 126123.0 94483.0 75480.0 79534.0 102242.0 77655.0 79019.0 True False 102457.06694915096 103601.0043773823 89155.84692374515 97047.29093092545 81365.66634529484 70760.22366789677 86612.37192222606 86442.84818743008 81759.68476417546 76252.56886151157 1.3436539709925248 1.3586559236520992 1.1692176179096112 1.2727084789389962 1.0670547571068665 0.9279716699959331 1.1358616924700564 1.1336385052735194 1.0722220376950946 1.0 16.21849832067084 -5.798106283099317 1.162877710824042 1.0611847302874016 1.3522082596354805 0.6910083904987295 0.0749133086979567 0.3254792045829788 0.866432901491845 0.02888791365073853 0.07426854900200992 1.5918191200445036e-06 5.798106283099317 0.29102352934807896 VGS(ph)PQPSSSGGEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VGSPQPSSSGGEK 13 0 V9GYB6;O94761 V9GYB6 RECQL4 ATP-dependent DNA helicase Q4 1 VGS(0.994)PQPS(0.002)S(0.004)SGGEK;VGS(0.883)PQPS(0.049)S(0.049)S(0.018)GGEK;VGS(0.955)PQPS(0.015)S(0.015)S(0.015)GGEK 141.06 7.5523e-05 23172700.0 101371.0 120948.0 95729.0 98027.0 120525.0 77519.0 94955.0 90025.0 81608.0 80069.0 True False 118531.10813148638 132954.91812251427 98011.54241425412 92534.86499782203 96908.99144595195 73453.76717559969 85960.17498533307 87661.93913937204 82801.36261283241 94584.87587414497 1.2531718949359765 1.405667839533084 1.0362284827086805 0.9783262296706855 1.0245717462789659 0.7765910405521658 0.9088152222107057 0.9268071489147524 0.8754186316532069 1.0 16.529321894554442 -5.438232312559259 2.8215189969115615 0.9213486364806218 1.331905983905307 0.80847808990813 0.07664283657921464 0.10649315301330571 1.6302923381928507 0.02144683701296342 0.05166186410798479 3.6455888512591423e-06 5.438232312559259 0.4105573474246851 VGS(ph)PQPSSSGGEK ddPTM_PC-9_Lapatinib_30min_R1 2 VGSPQPSSSGGEK 13 0 V9GYB6;O94761 V9GYB6 RECQL4 ATP-dependent DNA helicase Q4 1 VGS(0.831)PQPS(0.073)S(0.09)S(0.006)GGEK;VGS(0.995)PQPS(0.002)S(0.002)S(0.002)GGEK 129.29 9.4483e-05 18799900.0 58105.0 72962.0 54920.0 47842.0 50865.0 48693.0 52973.0 47564.0 50435.0 33373.0 True False 57276.41204484802 72793.06097177192 50404.689597330726 51360.46027623346 47873.22070443764 46610.51389892698 55715.682741120356 49773.997080918874 44754.4791959051 39141.47858327271 1.463317537251272 1.8597422378131718 1.2877564011818246 1.312174760260145 1.2230815604624727 1.190821491318067 1.4234434864944197 1.2716432511619533 1.14340287632954 1.0 15.25641063486175 -1.5228787452803454 0.20681441818836263 1.0718765317752226 3.968891468842517 0.5237495695626819 0.15207591651598873 42.601432686061436 0.5254746907042152 0.2697152673469333 40.4009549175457 0.029999999999999458 1.5228787452803454 2.8970149370672944 VGS(ph)PSGDAASSTPPSTR ddPTM_PC-9_AZD4547_30min_R2 3 VGSPSGDAASSTPPSTR 17 0 F8WEJ1;C9JF34;C9J222;F8WB78;F8WDE4;Q9H980;Q6PIY2;Q9NP87-2;Q9NP87;Q9NP87-3 F8WEJ1 POLM DNA-directed DNA/RNA polymerase mu 1 VGS(0.964)PS(0.035)GDAASSTPPSTR;VGS(0.59)PS(0.322)GDAAS(0.061)S(0.027)TPPSTR;VGS(0.559)PS(0.44)GDAAS(0.001)S(0.001)TPPSTR 124.04 4.135e-05 28838400.0 25985.9 30898.1 26708.3 42432.3 35248.6 32975.7 26697.9 36047.7 31983.7 36132.3 True False 34248.87565970241 40885.30657972253 26354.130491106796 32650.18880749991 30354.940325124786 30913.724266103163 29073.961379314536 30477.356258739237 33674.29308598231 34867.31917481619 0.982262946227295 1.17259679113079 0.7558404579076942 0.936412364936916 0.8705842904908334 0.8866102986326344 0.8338456201219492 0.8740951980257858 0.9657838309033069 1.0 15.089587824195242 -5.255306746353932 24.999997690356512 0.8846808551512312 1.0774298657983057 0.4807745816738467 0.07756572675523411 370.6556631843662 1510986.165465143 0.018363671690429725 0.04602946492466955 5.555117553971127e-06 5.255306746353932 0.1927490106470745 VGS(ph)PSGDAASSTPPSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VGSPSGDAASSTPPSTR 17 0 F8WEJ1;C9JF34;C9J222;F8WB78;F8WDE4;Q9H980;Q6PIY2;Q9NP87-2;Q9NP87;Q9NP87-3 F8WEJ1 POLM DNA-directed DNA/RNA polymerase mu 1 VGS(0.928)PS(0.053)GDAAS(0.013)S(0.006)TPPSTR 95.755 0.0016190999999999998 5831600.0 9153.6 7352.3 12207.0 9024.5 11822.0 10994.0 9239.2 8932.3 9460.5 8490.0 True False 10703.12368815906 8082.187754342058 12498.0611753053 8518.886522823761 9505.563964937084 10417.455286169114 8363.996089984617 8697.836589554161 9598.841914992396 10029.169793196974 1.0671993703226805 0.8058680749252445 1.2461710623129578 0.8494109381418914 0.9477917076830163 1.0387156166441138 0.8339669446675553 0.8672538972721463 0.9570923728406233 1.0 13.291914565279198 -6.45145078229396 1.1197762131449542 0.9180062991739482 1.0016072235994777 0.05711318380332675 0.12351246204869708 1.4677773287355134 3.878483918367374 0.05557053296983859 0.06832088697316242 3.536300950055289e-07 6.45145078229396 0.08360092442552958 VGS(ph)PSGDAASSTPPSTR ddPTM_PC-9_Lapatinib_30min_R1 3 VGSPSGDAASSTPPSTR 17 0 F8WEJ1;C9JF34;C9J222;F8WB78;F8WDE4;Q9H980;Q6PIY2;Q9NP87-2;Q9NP87;Q9NP87-3 F8WEJ1 POLM DNA-directed DNA/RNA polymerase mu 1 VGS(0.99)PS(0.01)GDAASSTPPSTR;VGS(0.973)PS(0.027)GDAASSTPPSTR;VGS(0.863)PS(0.137)GDAASSTPPSTR 191.15 8.0432e-09 29501400.0 49408.0 58435.0 64993.8 57745.0 60753.0 54104.0 58851.0 57985.7 61472.0 43945.1 True False 48703.43285968246 58299.69734773571 59650.26064732327 61991.759931673034 57179.62798499361 51790.09804258407 61898.01681984544 60679.92730920524 54548.37603114262 51540.951981834995 0.9449463191298333 1.1311334988201762 1.1573371921486104 1.2027670725508002 1.1094018598093784 1.004833943712116 1.2009482642396803 1.1773148336606427 1.0583501843421046 1.0 15.653431564142956 -4.7601176758346195 24.89903031150065 1.1243395012568649 0.9449460916064251 0.3374565923772158 0.07090895139961226 35.20208554815669 662893.7126646426 0.017458441289031245 0.10549945176057705 1.7373300204181322e-05 4.7601176758346195 -0.17939340965043982 VGS(ph)TENIK ddPTM_PC-9_AZD4547_30min_R2 3 VGSTENIK 8 0 E7EVA0;H7C4C5;H0Y2V1;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 VGS(0.697)T(0.303)ENIK;VGS(0.879)T(0.121)ENIK;VGS(0.5)T(0.5)ENIK 120.63 0.0034073999999999997 254184000.0 253360.0 279412.0 215000.0 230211.0 260076.0 290475.0 314710.0 225226.0 256866.0 262452.0 True False 333923.2097846217 369726.4648005353 212148.95952149548 177139.41067449457 223968.93663853809 272311.55233084655 342718.580325947 190422.4968786021 270443.4123576678 253263.63536417132 1.3184806784616705 1.4598482102213388 0.8376605635327138 0.699426944653082 0.884331208136099 1.0752098379196284 1.3532088009127217 0.7518746092576257 1.0678335717987837 1.0 17.9502804182617 -5.257584259426639 24.986522978796597 0.9561674257807565 1.3891644804817158 0.47851953082187537 0.17973635034354815 287.13362879561896 1861003.7900498789 0.04931974972502037 0.12067655369122944 5.526061839309455e-06 5.257584259426639 0.4329970547009593 VGS(ph)TENIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VGSTENIK 8 0 E7EVA0;H7C4C5;H0Y2V1;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 VGS(0.733)T(0.267)ENIK;VGS(0.708)T(0.292)ENIK;VGS(0.84)T(0.16)ENIK 110.54 0.0037603000000000003 205054000.0 269314.0 373290.0 245319.0 320958.0 344181.0 207814.0 375680.0 263907.0 230373.0 223055.0 True False 314903.5410060387 410347.7642123339 251168.33533748836 302975.7638198756 276741.2037739815 196915.86800436105 340092.87071233627 256979.72088257995 233741.76930210288 263493.10579759115 1.195111120850121 1.5573377640003714 0.9532254537635972 1.1498432298741585 1.0502787271655114 0.7473283500465736 1.2907088012146593 0.9752806249131443 0.8870887478993758 1.0 18.007405689195906 -5.273586349972542 24.78405848666641 1.0133821869776876 1.3762244484381414 0.46150697985277056 0.15952475184502796 500.35888404223493 1020907.4553285274 0.04038030584445947 0.08508346875558459 5.326153148716127e-06 5.273586349972542 0.36284226146045384 VGS(ph)TENIK ddPTM_PC-9_Lapatinib_30min_R1 2 VGSTENIK 8 0 E7EVA0;H7C4C5;H0Y2V1;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 VGS(0.5)T(0.5)ENIK;VGS(0.5)T(0.5)ENIK 117.25 0.0035548000000000003 434390000.0 274150.0 581420.0 364900.0 492190.0 506710.0 409690.0 506010.0 462590.0 363150.0 448360.0 True False 270240.570727047 580073.7577123371 334899.33055473317 528387.2944977082 476906.31403018953 392168.51373403554 532208.7218740548 484083.6201678224 322248.2228609682 525858.4285978522 0.5139036592940345 1.1030987166242527 0.6368621521341933 1.0048090241827994 0.9069100885228967 0.7457682380022183 1.0120760511401041 0.9205588307457235 0.6128041414496487 1.0 19.004314924428463 -4.7358149788110335 24.789265007914093 0.8767389217993939 0.5139017344830623 0.3294342688400749 0.15758693564558285 2690.3573137631824 2602523.88620849 0.036544116219638705 2.7344324040543966 1.8373209250158228e-05 4.7358149788110335 -0.36283718731633163 VGS(ph)TENIKHQPGGGR ddPTM_PC-9_Lapatinib_30min_R1 2 VGSTENIKHQPGGGR 15 1 E7EVA0;H7C4C5;H0Y2V1;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 VGS(0.5)T(0.5)ENIKHQPGGGR;VGS(0.5)T(0.5)ENIKHQPGGGR 65.105 0.014575 13310000.0 219847.0 67568.0 62220.0 73340.0 66385.0 49351.0 36816.0 32795.6 63172.0 42342.2 True False 216711.94146499792 67411.55044736563 57104.51177614558 78733.66825506781 62480.36481793167 47240.37277279992 38722.1523379285 34319.403302224 56056.90412934901 49660.99285256497 4.363826194703331 1.357434609644214 1.1498866312576381 1.5854227580349565 1.2581376494711904 0.9512571146744598 0.7797297257605779 0.6910736441398274 1.128791449977096 1.0 15.599825484583196 -4.757281014158087 4.208745478183391 1.0762800465994036 4.704743942174931 0.9452865532336524 0.2364486749014273 0.0563514550377754 1.9814314051937076 0.0690880431560326 0.6380258831735298 1.748714800794936e-05 4.757281014158087 3.628463895575527 up VGSAQPS(ph)PPDDLDAGGLAQR ddPTM_PC-9_AZD4547_30min_R2 2 VGSAQPSPPDDLDAGGLAQR 20 0 Q8N3D4;E9PIH6;H0YDZ9;A0A0U1RQH4 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 VGS(0.171)AQPS(0.829)PPDDLDAGGLAQR;VGS(0.045)AQPS(0.955)PPDDLDAGGLAQR 164.74 5.2002e-08 10815600.0 33160.0 41227.0 48925.0 62699.0 52778.0 44256.0 40865.0 54735.0 34536.0 38934.0 True False 43704.19022915242 54552.82151207419 48276.222532972904 48244.71423989359 45450.68571459392 41488.665323879766 44501.90583400524 46276.963435173166 36361.50245335861 37570.93251058728 1.1632447562177708 1.4519954088629956 1.28493543564214 1.2840968007993547 1.209730040684675 1.1042756341538367 1.1844770108238558 1.2317225137313954 0.967809421368824 1.0 15.197329303666056 -7.373134784140709 0.40661455783011835 0.9882780554282848 1.3412301865620702 0.5539685314940554 0.09014096856754622 0.8871131264794291 0.35592922028066776 0.09949575363238933 0.10676834465536365 4.235115080277635e-08 7.373134784140709 0.3529521311337853 VGSGQGGS(ph)PCWK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VGSGQGGSPCWK 12 0 A0A669KBI7;Q9UMN6;Q9UMN6-2 A0A669KBI7 KMT2B Histone-lysine N-methyltransferase 2B 1 VGS(0.001)GQGGS(0.999)PCWK;VGSGQGGS(1)PCWK 135.02 5.9151e-05 20275000.0 56882.0 57823.0 53144.0 61902.0 75071.0 61742.0 70921.0 59473.0 54485.0 52042.0 True False 66510.99912928937 63563.28530110594 54411.15450974236 58433.831628991764 60361.37645168268 58504.14082942091 64202.849456424636 57911.89676685224 55281.74004950693 61476.80263575469 1.0818877410291148 1.0339393490860853 0.8850680610721453 0.9505021263907901 0.9818561451433832 0.9516457968065357 1.0443426903123372 0.9420121783166856 0.8992292650131298 1.0 15.907754512998867 -5.041889757939961 7.114985954450088 0.9582575998359832 1.0707751595270563 0.47665602277709995 0.0436459939187106 0.1677927330963194 24.510388480795495 0.01133734017767439 0.031877296625657865 9.080510021571743e-06 5.041889757939961 0.11251755969107302 VGSGS(ph)LDNLGR ddPTM_PC-9_AZD4547_30min_R2 1 VGSGSLDNLGR 11 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 VGS(0.003)GS(0.997)LDNLGR 101.38 0.0037575000000000004 8108800.0 13340.0 10989.0 16645.0 34949.0 28187.0 28766.0 22671.0 25472.0 25779.0 23483.0 True False 17581.842510762763 14540.97934839264 16424.276424350195 26892.04800666743 24273.721593036113 26967.25747258508 24688.67508045353 21535.887688329796 27141.62531112842 22660.8673176689 0.7758680311875807 0.6416779704214982 0.7247858695833775 1.186717508632136 1.07117354568815 1.1900364224611317 1.0894850022445313 0.9503558441268509 1.1977310899290174 1.0 14.467915459196579 -5.751697581306336 24.8667796725293 1.098231208016717 0.7068671722511038 0.820128871313065 0.08234998723043208 70.68300121877556 180422.53240470003 0.021766006943279216 0.03710377841673906 1.7713419937023238e-06 5.751697581306336 -0.39136403576561307 VGSGS(ph)LDNLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VGSGSLDNLGR 11 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 VGS(0.088)GS(0.912)LDNLGR;VGS(0.01)GS(0.99)LDNLGR;VGS(0.023)GS(0.977)LDNLGR 130.69 0.00019665 30894300.0 36288.9 39973.7 58786.0 57723.0 83895.0 80246.0 71818.0 66909.0 74644.0 57476.0 True False 42431.89403155429 43942.02475902009 60187.681187146474 54488.96745049098 67456.37699529657 76037.75849499053 65014.879122707105 65152.70964594545 75735.52728742592 67895.94382023424 0.6249547711406702 0.6471966112639053 0.886469467844844 0.8025364165311487 0.9935258750345749 1.119916068864336 0.9575664681066186 0.9595964939886252 1.1154646805993047 1.0 16.051037768375465 -5.463260379277693 0.8323428037551434 1.0304842395063984 0.5458988371110016 0.8169296448268645 0.0701092431914243 0.45565582191357773 0.4613114185790948 0.029930607489399862 0.1702475497112936 3.4414353920817546e-06 5.463260379277693 -0.4845854023953968 VGSGS(ph)LDNLGR ddPTM_PC-9_Lapatinib_30min_R1 2 VGSGSLDNLGR 11 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 VGS(0.025)GS(0.975)LDNLGR;VGS(0.019)GS(0.981)LDNLGR 139.19 0.00010879 22581000.0 91623.0 73611.0 95341.0 64869.0 79089.0 105070.0 65453.0 88047.0 89099.0 66424.0 True False 90316.43921839965 73440.5582521465 87502.43100690276 69639.68265664032 74437.1405149567 100576.40103013294 68841.8360760113 92137.98505137647 79063.73236593543 77905.2998955835 1.1593105904149115 0.9426901423982565 1.1231897075575383 0.893901733899727 0.9554823691677565 1.291008457254327 0.8836604976590814 1.1826921297378874 1.0148697517614922 1.0 16.249433857682178 VGSLPLEKGS(ph)PVTTTK ddPTM_PC-9_AZD4547_30min_R2 2 VGSLPLEKGSPVTTTK 16 1 Q7Z2K8;Q7Z2K8-2 Q7Z2K8 GPRIN1 G protein-regulated inducer of neurite outgrowth 1 1 VGSLPLEKGS(0.791)PVT(0.092)T(0.092)T(0.025)K;VGSLPLEKGS(0.796)PVT(0.138)T(0.048)T(0.017)K 81.316 0.0034538000000000004 43969000.0 137236.0 228000.0 253940.0 256590.0 277900.0 185806.0 201900.0 250830.0 193370.0 201973.0 True False 180874.19331387087 301696.5412169916 250572.58967855168 197437.13977598204 239318.3819031725 174187.5214472339 219868.7088678738 212069.986999991 203591.14342732064 194901.9867457966 0.9280264215560734 1.5479397940180217 1.285633840179188 1.0130073226677363 1.227890930713326 0.8937185523635539 1.128098859015944 1.0880853014422371 1.0445821862906763 1.0 17.572389271311216 -5.753674852221863 24.901926698238682 1.0634976264577087 1.2832740774114906 0.23016584687799257 0.16242579964074155 213.394426450151 684377.8562252979 0.0419755886435995 0.07099547635778582 1.7632956973271113e-06 5.753674852221863 0.21977645095378184 VGSLPLEKGS(ph)PVTTTK ddPTM_PC-9_Lapatinib_30min_R1 1 VGSLPLEKGSPVTTTK 16 1 Q7Z2K8;Q7Z2K8-2 Q7Z2K8 GPRIN1 G protein-regulated inducer of neurite outgrowth 1 1 VGSLPLEKGS(0.949)PVT(0.03)T(0.017)T(0.004)K 119.47 0.00052213 4291300.0 25559.0 22336.0 15296.0 14187.0 13838.0 10939.0 7703.1 8608.6 14898.0 6126.3 True False 25194.523973053456 22284.28236431976 14038.42192426748 15230.359306444632 13024.076046554763 10471.164470054464 8101.928826442229 9008.586983239384 13220.030357105066 7185.222792218368 3.5064360148079543 3.10140450877233 1.953790763380526 2.1196780874963523 1.8126196533056569 1.457319386309745 1.1275821308166893 1.253765853022084 1.8398915022401845 1.0 12.810817175686436 -3.6505230757359146 0.43057341494039025 1.2394364002653044 9.185890799414828 0.8905043601239551 0.25851942038567477 4.010521527596799 0.27275394347309956 0.1818560221283906 19.994747444272882 0.00022360263868854497 3.6505230757359146 7.946454399149523 VGSLPLEKGSPVT(ph)TTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VGSLPLEKGSPVTTTK 16 1 Q7Z2K8;Q7Z2K8-2 Q7Z2K8 GPRIN1 G protein-regulated inducer of neurite outgrowth 1 1 VGSLPLEKGS(0.099)PVT(0.65)T(0.205)T(0.046)K;VGSLPLEKGS(0.009)PVT(0.714)T(0.212)T(0.064)K 63.43600000000001 0.024097999999999998 43775000.0 243470.0 200694.0 211320.0 256060.0 385100.0 224620.0 243960.0 221730.0 222030.0 207790.0 True False 284684.662248305 220617.57397956072 216358.67023556272 241713.78835772048 309642.4194634812 212840.53177908921 220850.34268255354 215909.8224423545 225276.76871050752 245460.682135265 1.1597974053189708 0.8987898675274841 0.8814392119888873 0.9847352588408447 1.2614746148747675 0.8671064136528394 0.8997381607570473 0.8796106185485705 0.9177712974266289 1.0 17.905132426751827 VGSLPLEKGSPVT(ph)TTK ddPTM_PC-9_Lapatinib_30min_R1 1 VGSLPLEKGSPVTTTK 16 1 Q7Z2K8;Q7Z2K8-2 Q7Z2K8 GPRIN1 G protein-regulated inducer of neurite outgrowth 1 1 VGSLPLEKGS(0.097)PVT(0.74)T(0.136)T(0.026)K 69.729 0.015128999999999998 19951000.0 198590.0 167440.0 90304.0 95905.0 94688.0 63392.0 67996.0 56124.0 115580.0 44304.0 True False 195758.07018305463 167052.302967483 82879.55370352062 102958.17362970124 89118.63800377048 60680.87193396953 71516.50017301679 58731.725930735236 102562.16328864306 51961.88736863076 3.7673394885427736 3.2149006017116304 1.595006607738324 1.9814171278901 1.7150770019483768 1.1677957635272962 1.3763260688677579 1.1302846933576052 1.973795958584821 1.0 15.665166213104923 -4.928578707623424 1.0172322296390288 1.3965029570836085 4.814520578802021 0.8550360313183618 0.3312104405874449 0.5169102814775328 0.5093099173799126 0.10750072131031214 1.8304015748913827 1.1787488780464144e-05 4.928578707623424 3.4180176217184126 VGSLT(ph)PPSSPK ddPTM_PC-9_AZD4547_30min_R2 1 VGSLTPPSSPK 11 0 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 1 VGS(0.31)LT(0.686)PPS(0.004)SPK 91.09299999999999 0.02049 14751000.0 312760.0 212650.0 176470.0 264540.0 225820.0 187870.0 116680.0 143000.0 144080.0 153460.0 True False 412211.1741878685 281384.95390260237 174129.8924965502 203554.39010225757 194468.79093693628 176122.45920095092 127064.29396088902 120902.63581309494 151695.77465485028 148087.41210958833 2.7835665997243715 1.9001274307796707 1.1758588391543354 1.3745556573817517 1.3132027102548365 1.1893141806719938 0.858035751660366 0.8164275011006608 1.0243664366461591 1.0 17.17608948671179 -1.5228787452845527 0.5949334374219276 0.9842614073818837 111.39553560387958 0.9306827129651897 0.14825135274100582 42.952005449473546 0.33873299717235733 0.07572273805418225 6155.313404755158 0.02999999999970883 1.5228787452845527 110.4112741964977 up VGSLT(ph)PPSSPK ddPTM_PC-9_Lapatinib_30min_R1 1 VGSLTPPSSPK 11 0 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 1 VGS(0.289)LT(0.71)PPS(0.002)SPK 105.25 0.0063119 9981700.0 89604.0 68726.0 76457.0 64333.0 90802.0 98774.0 88934.0 75032.0 90043.0 88388.0 True False 88326.23052863895 68566.86916951275 70171.00059255495 69064.26342859684 85461.20488360061 94549.66627343994 93538.56736259587 78518.26063778289 79901.40914517474 103665.74803039334 0.8520290665605668 0.6614226055592625 0.6768966792385639 0.6662206634379194 0.8243919183272047 0.912062740778365 0.902309288649243 0.7574175861323302 0.7707599729251823 1.0 16.6615797696548 -6.385199777413545 5.03432208766317 0.8565359646647256 0.7083660340365224 0.4326379341974257 0.08292260255404284 0.23358656607083808 8.62358015563126 0.026605427496072687 0.030206361187427824 4.1190799598052134e-07 6.385199777413545 -0.14816993062820316 VGSPLDYSLVDLPS(ph)TNGQSPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VGSPLDYSLVDLPSTNGQSPGK 22 0 Q96T23-3;Q96T23-2;Q96T23 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 VGSPLDYSLVDLPS(0.36)T(0.36)NGQS(0.28)PGK 70.449 0.0010244000000000002 4150700.0 15894.0 16985.0 14474.0 15409.0 17247.0 13608.0 17058.0 14904.0 15698.0 13016.0 True False 18584.540279190707 18671.158550045555 14819.11505295068 14545.683686652032 13867.574158625435 12894.3725244851 15442.142750774683 14512.785792093327 15927.553552301735 15375.69776540069 1.2086957328863959 1.2143291858962335 0.963801141194225 0.9460177943523054 0.9019151111197747 0.8386203163735947 1.0043214289450664 0.943878190995069 1.035891430445704 1.0 13.908364262511325 -5.274176560895422 5.42271070687312 0.9468592460458124 1.2141101049771206 0.7907810745998853 0.052850643820798356 0.06682946628703702 6.985219640183963 0.014366649616195682 0.033735487636542084 5.318919764914016e-06 5.274176560895422 0.2672508589313082 VGSPQPSS(ph)SGGEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VGSPQPSSSGGEK 13 0 V9GYB6;O94761 V9GYB6 RECQL4 ATP-dependent DNA helicase Q4 1 VGS(0.286)PQPS(0.223)S(0.394)S(0.097)GGEK 66.19 0.038011 7663900.0 24352.0 22477.0 22684.0 28390.0 21837.0 23059.0 31660.0 23585.0 19669.0 17513.0 True False 28474.31262607603 24708.368014682008 23224.872589549075 26799.40034162187 17558.196608216134 21849.74544695049 28660.93560144957 22965.918740373116 19956.621914907802 20687.96826716827 1.3763706642601854 1.1943351660053585 1.1226270404913015 1.2954099694822336 0.8487153683467761 1.0561571423920808 1.385391510240006 1.1101099172130857 0.9646487106507644 1.0 14.336504346892907 -1.5228787452821018 0.7232813145535095 1.0952328362219987 42.12789790550933 0.2679820933588296 0.14479256765933637 495.6495931342818 2.39324523133265 0.05772356524333406 33012.948825585314 0.029999999999878135 1.5228787452821018 41.03266506928733 VGSPS(ph)GDAASSTPPSTR ddPTM_PC-9_AZD4547_30min_R2 1 VGSPSGDAASSTPPSTR 17 0 F8WEJ1;C9JF34;C9J222;F8WB78;F8WDE4;Q9H980;Q6PIY2;Q9NP87-2;Q9NP87;Q9NP87-3 F8WEJ1 POLM DNA-directed DNA/RNA polymerase mu 1 VGS(0.297)PS(0.44)GDAAS(0.201)S(0.034)T(0.001)PPS(0.014)T(0.014)R 125.33 3.8688e-05 5082800.0 5222.3 6410.5 6219.8 6753.1 7745.6 7172.9 7778.7 6452.6 5645.8 5908.9 True False 6882.882769412022 8482.568760840028 6137.3213880548765 5196.277129354943 6670.257138788105 6724.377429086611 8470.989230661366 5455.498935997045 5944.225461870858 5702.031209529185 1.207093142161237 1.4876398337953733 1.0763394942136126 0.9113028214701754 1.1698036881385059 1.1792950936236355 1.485609060943883 0.9567641311538005 1.042475083604755 1.0 12.477260220414585 -1.5228787452803552 0.09375518352959651 0.9115925603658163 1.9165032190779898 0.1307671691407728 0.17810156000857588 346.3252853724693 2.33124943678765 3.1033935966760806 44.72462641407332 0.029999999999998785 1.5228787452803552 1.0049106587121734 VGSPS(ph)GDAASSTPPSTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VGSPSGDAASSTPPSTR 17 0 F8WEJ1;C9JF34;C9J222;F8WB78;F8WDE4;Q9H980;Q6PIY2;Q9NP87-2;Q9NP87;Q9NP87-3 F8WEJ1 POLM DNA-directed DNA/RNA polymerase mu 1 VGS(0.288)PS(0.711)GDAASSTPPSTR 140.49 8.9609e-05 11115000.0 10003.0 9870.8 10480.0 11071.0 12879.0 8783.3 10679.0 11997.0 10425.0 7960.3 True False 11696.310331744347 10850.707790155413 10729.88294562132 10450.727762666273 10355.452402675077 8322.688285884044 9667.407810735307 11682.091461872214 10577.445902837659 9403.439376299872 1.243833225662448 1.1539084111610471 1.1410594056324301 1.111372907768827 1.1012409383714037 0.885068532143705 1.028071477240629 1.2423211331925408 1.1248486303316545 1.0 13.198972814173896 -5.107948419102648 1.0112448992872236 1.0694305962405863 1.267666083276837 0.2874086824452502 0.08754472445679513 1.8682322022965012 2.2003402937974825 0.03329715364050089 0.3576966743884318 7.799227359821672e-06 5.107948419102648 0.1982354870362506 VGSPS(ph)GDAASSTPPSTR ddPTM_PC-9_Lapatinib_30min_R1 1 VGSPSGDAASSTPPSTR 17 0 F8WEJ1;C9JF34;C9J222;F8WB78;F8WDE4;Q9H980;Q6PIY2;Q9NP87-2;Q9NP87;Q9NP87-3 F8WEJ1 POLM DNA-directed DNA/RNA polymerase mu 1 VGS(0.021)PS(0.972)GDAAS(0.003)S(0.004)TPPSTR 112.57 0.00025125 6133000.0 8598.0 8555.1 8125.7 7854.7 8467.6 8246.4 7990.7 8084.3 9699.6 6553.0 True False 8475.390943319911 8535.291191573775 7457.636312109066 8432.360840511074 7969.552415942122 7893.720695297299 8404.419347204617 8459.926091188136 8607.128906683876 7685.677318676364 1.1027513375723603 1.1105450876571192 0.9703290943514955 1.0971525983819608 1.0369355992315648 1.0270689710216412 1.0935170706141533 1.100739172412343 1.1198920472198806 1.0 12.907956691128135 -7.297852239656495 24.184726076661693 1.086932012729896 1.05678682249811 0.031192405856152128 0.04925625341261 1149.5022369978092 763471.6739190225 0.02032422271580148 0.013703131643963676 5.0367194433001144e-08 7.297852239656495 -0.030145190231785968 VGST(ph)ENIK ddPTM_PC-9_AZD4547_30min_R2 1 VGSTENIK 8 0 E7EVA0;H7C4C5;H0Y2V1;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 VGS(0.371)T(0.629)ENIK 107.11 0.0093286 173320000.0 87181.0 96353.0 72711.0 87325.0 93411.0 104980.0 118530.0 98650.0 111460.0 97909.0 True False 114902.74452254965 127497.22296438938 71746.80463147651 67193.57040780087 80442.49504122788 98415.5840044488 129078.94037696415 83405.90925148118 117351.54804990008 94481.23571118046 1.2161435406475385 1.3494449136348665 0.7593762305438003 0.7111842886264188 0.8514123935374048 1.0416415837880788 1.3661859882055878 0.8827775020475449 1.242061951948129 1.0 16.52774021328043 -8.267285889693344 24.815198180142833 1.121030915085307 1.0204581586544794 0.029804250105519903 0.22519881635653405 2313.096792094914 9817645.948037278 0.21388554189353667 0.061079958354584796 5.403984694383518e-09 8.267285889693344 -0.10057275643082764 VGST(ph)ENIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VGSTENIK 8 0 E7EVA0;H7C4C5;H0Y2V1;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 VGS(0.203)T(0.797)ENIK 149.33 0.001836 119080000.0 214610.0 293640.0 183660.0 229810.0 266610.0 150960.0 307360.0 230240.0 160700.0 183100.0 True False 250939.23425928727 322790.6386008468 188039.15093442844 216934.49075407302 214369.68437589923 143043.3918501082 278244.6357063027 224196.44395944534 163049.9334854689 216294.58058119757 1.1601734707591715 1.4923658176431764 0.8693659842477562 1.0029585122805942 0.9911005805132703 0.6613359958707302 1.2864151980074643 1.0365328773241334 0.7538327268641829 1.0 17.72263799241086 -5.268974109656785 24.992680106947702 0.9565345938869341 1.3262696504520326 0.4204628901458104 0.1764836318680322 480.13638917077816 1592614.8727755717 0.04530362078572259 0.09731570960910545 5.38301872274265e-06 5.268974109656785 0.36973505656509853 VGST(ph)ENIK ddPTM_PC-9_Lapatinib_30min_R1 1 VGSTENIK 8 0 E7EVA0;H7C4C5;H0Y2V1;F8W9U4;P27816;P27816-6;P27816-2;P27816-5 E7EVA0;P27816 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 VGS(0.086)T(0.914)ENIK 97.81299999999999 0.013932 4387200.0 17226.0 41132.0 31027.0 30545.0 41396.0 31740.0 36746.0 38550.0 30163.0 33556.0 True False 16980.354081138485 41036.761381142554 28476.079827683534 32791.38119513297 38961.168667667334 30382.554189553775 38648.52808044113 40341.173733694 26765.72530952882 39356.10988944055 0.43145407736790575 1.0427036995379702 0.723549149234483 0.8331967078873074 0.9899649324365978 0.7719907855452343 0.9820210429590942 1.02502950233193 0.6800907250416588 1.0 15.264300005699889 -4.749379693848386 24.99974536429326 0.8897309871100917 0.43145303907422317 0.5446034385110212 0.12690716724390114 422.8457552842958 876506.1403876062 0.0299638911428659 0.4937989953468925 1.7808211549739365e-05 4.749379693848386 -0.4582779480358685 VGSTSENITQK ddPTM_PC-9_Lapatinib_30min_R1 2 VGSTSENITQK 11 0 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDT5;A0A2R8YDH3;A0A2R8Y7T2;O15523-2;O15523 A0A2R8Y5G6 DDX3X;DDX3Y ATP-dependent RNA helicase DDX3X;ATP-dependent RNA helicase DDX3Y 0 ; 144.17 3.3178e-05 0.0 15006.3 17416.7 20704.4 16195.0 17270.9 13293.7 13535.5 12853.1 17819.3 12101.2 False True 14792.307410181611 17376.37270122885 19002.164153295234 17386.034324936278 16255.059617895835 12725.159440128264 14236.301960289851 13450.301948548438 15812.302788452305 14192.876296164555 1.0422346465585024 1.2243024133117115 1.3388522352181937 1.2249831508525606 1.1452970686631405 0.896587779290874 1.0030596803085665 0.9476797844129179 1.1141013603229515 1.0 13.792879371887182 -6.585370564816876 5.350807275521601 0.9904318972934686 1.2147755747421103 0.5950095414403498 0.08473521285214893 0.1386374749562263 7.8370433506381785 0.029000714389941378 0.029150396824568513 2.5979419050069767e-07 6.585370564816876 0.2243436774486417 VGTEGLVDS(ph)FSQGLER ddPTM_PC-9_AZD4547_30min_R2 2 VGTEGLVDSFSQGLER 16 0 T1ECW5;O75170-6;O75170-2;O75170-4;O75170-3;O75170-5;O75170 T1ECW5 PPP6R2 Serine/threonine-protein phosphatase 6 regulatory subunit 2 1 VGTEGLVDS(0.982)FS(0.018)QGLER;VGTEGLVDS(0.987)FS(0.013)QGLER 115.66 0.00017251 4796200.0 11389.3 11504.3 15388.8 14154.5 13721.599999999999 16078.8 14207.0 16825.2 13744.0 13983.900000000001 True False 15010.860487843356 15222.839996151917 15184.734457136701 10891.398709845027 11816.592692056773 15073.390094215425 15471.395477394162 14225.251944632782 14470.479781067885 13494.327917367902 1.1123829641432974 1.1280917500573948 1.1252679310981586 0.8071093852571368 0.8756710793168293 1.1170167337356007 1.1465110061155155 1.0541652783110556 1.0723379385529548 1.0 13.720065504970322 VGVASS(ph)EELAR ddPTM_PC-9_Lapatinib_30min_R1 1 VGVASSEELAR 11 0 O95721 O95721 SNAP29 Synaptosomal-associated protein 29 1 VGVAS(0.034)S(0.966)EELAR 97.779 0.0052492 1287200.0 11816.0 14003.0 10224.0 10201.0 12841.0 7639.0 10512.0 10601.0 12093.0 7668.3 True False 11647.501673210983 13970.576913841758 9383.422185781308 10951.21556953843 12085.717626377338 7312.297777378748 11056.259924388974 11093.561160853182 10730.958995064546 8993.75543763252 1.2950654211114534 1.5533641103231195 1.0433263669276915 1.2176465821735956 1.3437898895723956 0.8130416518534561 1.2293262810022971 1.2334737405060467 1.1931566373445128 1.0 13.134707938769989 -5.264875205211462 24.99976900824052 1.1449486268558435 1.424214769390069 0.36059270212452466 0.15393560634117207 297.3550158576357 2163634.0209854958 0.039398086565672216 0.08762158924416548 5.434064572422195e-06 5.264875205211462 0.27926614253422555 VGVEASEETPQTS(ph)SSSARPGTPSDHQSQEASQFER ddPTM_PC-9_AZD4547_30min_R2 1 VGVEASEETPQTSSSSARPGTPSDHQSQEASQFER 35 1 Q6Y7W6;I1E4Y6;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 VGVEAS(0.001)EET(0.012)PQT(0.07)S(0.187)S(0.187)S(0.187)S(0.187)ARPGT(0.124)PS(0.043)DHQS(0.002)QEAS(0.001)QFER 46.06 0.0041866 44749000.0 0.0 0.0 9096.8 30213.0 14743.0 17621.0 1100.8 14594.0 9083.1 12117.0 True False 0.0 0.0 8976.17048825647 23247.859636196838 12696.188932704126 16519.156084419847 1198.7690674678333 12338.832636757417 9563.214122483827 11692.787518127752 0.0 0.0 0.7676672884323252 1.9882221925400456 1.0858137046466263 1.4127645831936653 0.10252209454839901 1.055251591430023 0.8178729073505894 1.0 13.513331283686007 -5.343205202231198 4.182182915453119 1.0625436949211275 1.9049162856349685e-10 0.4678029935612208 0.44594640792592566 0.19280566079674394 6.187846908585838 0.12424570928437897 0.28271573292307434 4.5372718189803955e-06 5.343205202231198 -1.062543694730636 VGVEASEETPQTSSSS(ph)ARPGTPSDHQSQEASQFER ddPTM_PC-9_AZD4547_30min_R2 1 VGVEASEETPQTSSSSARPGTPSDHQSQEASQFER 35 1 Q6Y7W6;I1E4Y6;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 VGVEASEET(0.001)PQT(0.12)S(0.12)S(0.12)S(0.12)S(0.415)ARPGT(0.094)PS(0.009)DHQS(0.001)QEASQFER 78.079 1.1316e-08 15856000.0 2403.2 0.0 37641.0 115830.0 58600.0 48703.0 12532.0 60952.0 22896.0 41032.0 True False 3167.3676103347125 0.0 37141.85574580749 89127.18305566079 50464.40150962908 45657.59371088472 13647.323722299128 51533.26893762083 24106.23581688957 39595.48216916877 0.07999315671425261 0.0 0.9380326671391866 2.250943243344569 1.2744989767777966 1.1531010915794895 0.34466870902068947 1.3014936582271874 0.6088127861127555 1.0 15.273048208239082 -5.312498972955434 4.848098326961558 1.1493612636499504 0.03354211753341877 0.45183635024122193 0.47276428031984974 0.17533915083194723 9.210969739952242 0.13236314487782422 0.2976913160225608 4.869686767760324e-06 5.312498972955434 -1.1158191461165317 VGVEASEETPQTSSSS(ph)ARPGTPSDHQSQEASQFER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VGVEASEETPQTSSSSARPGTPSDHQSQEASQFER 35 1 Q6Y7W6;I1E4Y6;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 VGVEASEETPQT(0.121)S(0.121)S(0.121)S(0.121)S(0.392)ARPGT(0.121)PSDHQSQEASQFER;VGVEASEET(0.001)PQT(0.168)S(0.168)S(0.168)S(0.168)S(0.193)ARPGT(0.132)PS(0.003)DHQSQEASQFER 122.31 9.848999999999999e-25 32336000.0 13614.8 12816.8 135007.0 124868.0 151790.0 134854.0 64536.0 86543.0 110502.0 57493.0 True False 15919.516735442667 14089.16720071968 138226.07889689886 117872.05078751786 122047.83913363218 127782.0188431006 58422.68287982149 84271.3379498882 112117.88270075481 67916.02578566245 0.23440000428887564 0.20744981817964386 2.0352498147216287 1.7355557752968735 1.7970403556710666 1.8814707922747191 0.8602193989412574 1.2408166846488016 1.6508310285202772 1.0 16.051464419313962 -5.247967010839641 24.691023855346703 1.539951941073863 0.22092457509736702 0.6729157734864757 0.3635978987088662 394.1130425736499 722293.529149485 0.09762189747830968 0.25505584110498336 5.649798892518775e-06 5.247967010839641 -1.319027365976496 VGVEASEETPQTSSSS(ph)ARPGTPSDHQSQEASQFER ddPTM_PC-9_Lapatinib_30min_R1 1 VGVEASEETPQTSSSSARPGTPSDHQSQEASQFER 35 1 Q6Y7W6;I1E4Y6;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 VGVEASEETPQT(0.027)S(0.027)S(0.027)S(0.051)S(0.415)ARPGT(0.415)PS(0.037)DHQSQEASQFER 79.04 9.4599e-09 22446000.0 21740.0 8956.2 65820.0 10431.0 38831.0 61138.0 25891.0 23724.0 78944.0 22512.0 True False 21429.98361337228 8935.462469167289 60408.533672547455 11198.13053679594 36547.03692468332 58523.27025963891 27231.509294364045 24826.303648720008 70052.49540282604 26403.169204645557 0.8116443691767782 0.3384238611626638 2.287927377366455 0.42412069740573655 1.38419129315177 2.216524456061961 1.0313727523881013 0.940277413529278 2.653185110463956 1.0 14.688423487974527 -5.232924522038829 24.85949490937736 1.457474546449774 0.5750339275764731 0.22743741161581144 0.6737233260747255 1006.7016026545324 877647.6007219534 0.16504720801329592 0.43649113616257684 5.848917262349552e-06 5.232924522038829 -0.8824406188733009 VGVEASEETPQTSSSSARPGT(ph)PSDHQSQEASQFER ddPTM_PC-9_AZD4547_30min_R2 2 VGVEASEETPQTSSSSARPGTPSDHQSQEASQFER 35 1 Q6Y7W6;I1E4Y6;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 VGVEASEET(0.001)PQT(0.104)S(0.137)S(0.137)S(0.137)S(0.137)ARPGT(0.288)PS(0.055)DHQS(0.001)QEASQFER;VGVEASEET(0.001)PQT(0.24)S(0.086)S(0.086)S(0.086)S(0.086)ARPGT(0.328)PS(0.086)DHQS(0.001)QEASQFER 77.233 1.9172e-08 62941000.0 2236.4 2156.3 62305.0 177278.0 97425.0 62446.0 20323.0 99068.0 35118.0 64853.0 True False 2947.528679990244 2853.281806255259 61478.7949906362 136409.29601779708 83899.22042791142 58541.24174835038 22131.707629132234 83759.3169561657 36974.26578518206 62582.51620971687 0.04709827693908856 0.045592315219378225 0.9823637449254669 2.1796710052482275 1.3406175639656497 0.9354248645448515 0.35364042498655485 1.338382059862924 0.5908082324667101 1.0 15.933472044684732 -5.285810335013472 5.209278395216048 1.1233186245475362 0.0360966698105673 0.44895122556499767 0.46298850135308023 0.1589917910279421 13.101412264934288 0.13083787217599613 0.30152933236561263 5.178329304547502e-06 5.285810335013472 -1.0872219547369688 VGVEASEETPQTSSSSARPGT(ph)PSDHQSQEASQFER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VGVEASEETPQTSSSSARPGTPSDHQSQEASQFER 35 1 Q6Y7W6;I1E4Y6;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 VGVEASEETPQT(0.097)S(0.132)S(0.132)S(0.132)S(0.132)ARPGT(0.335)PS(0.039)DHQS(0.001)QEASQFER 72.469 2.3415e-06 22109000.0 0.0 6522.1 58455.0 63325.0 74130.0 66998.0 37728.0 44411.0 50870.0 33727.0 True False 0.0 7169.570984942723 59848.78889182203 59777.10555242005 59604.75864665755 63484.506936761645 34154.13071293395 43245.25830734411 51613.87751341503 39841.43811721491 0.0 0.17995261526076428 1.502174412372987 1.5003751967123704 1.4960493763126286 1.5934291013790216 0.8572514529332826 1.0854341698237662 1.295482290613235 1.0 15.281982103439589 -5.228681710094562 7.220803553623757 1.3044515850512373 0.0792035621570833 0.8064881947172463 0.23534497938120627 0.09824317773775722 17.45258838636145 0.06516900976605372 0.17019019778670658 5.906337909456445e-06 5.228681710094562 -1.225248022894154 VGVEASEETPQTSSSSARPGT(ph)PSDHQSQEASQFER ddPTM_PC-9_Lapatinib_30min_R1 1 VGVEASEETPQTSSSSARPGTPSDHQSQEASQFER 35 1 Q6Y7W6;I1E4Y6;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 VGVEASEET(0.001)PQT(0.147)S(0.046)S(0.046)S(0.046)S(0.046)ARPGT(0.656)PS(0.011)DHQSQEASQFER 92.089 1.3485e-12 8881700.0 14699.0 3260.5 46062.0 8862.6 31000.0 47172.0 18562.0 15856.0 48518.0 14724.0 True False 14489.38956453354 3252.9505125745245 42274.960164461896 9514.38516876692 29176.640948344957 45154.563523302786 19523.04953543647 16592.727645173854 43053.391922810006 17269.02378150324 0.8390392964802704 0.18836910260432568 2.4480225807403415 0.5509509564146716 1.6895362075762441 2.614772212640508 1.1305242139018594 0.9608376162494047 2.4930993475684633 1.0 14.075898909122055 -5.242789568559679 24.99575798611568 1.5932089854114933 0.5137040969613665 0.2837089415318349 0.6969386908226171 1049.484633358826 1406586.491014499 0.17211835690420882 0.4535915308295629 5.717556059100327e-06 5.242789568559679 -1.0795048884501268 VGVNGFGR ddPTM_PC-9_AZD4547_30min_R2 2 VGVNGFGR 8 0 P04406 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 115.46 0.016738999999999997 150590000.0 163677.0 175910.0 251588.0 304110.0 280406.0 259070.0 208813.0 303196.0 236445.0 243720.0 False True 215722.88130690556 232769.46739246036 248251.7787353212 234002.13795266324 241476.4670598812 242870.3119454428 227396.95247561805 256344.02495095925 248942.99998796533 235187.43698259434 0.9172381147334443 0.9897189678957514 1.0555486378028505 0.9949601941109685 1.0267405017800857 1.0326670295889022 0.9668754223995696 1.0899562843993689 1.0584876606584603 1.0 17.843451472166436 -4.854018901925027 2.9668684281625017 1.02808481372672 0.9075069248605994 0.5039645714222147 0.03356417172084044 0.27337627048220997 3.8284597434172785 0.008689462873290497 0.0729847075010431 1.3995264092521668e-05 4.854018901925027 -0.12057788886612064 VGVNGFGR ddPTM_PC-9_Lapatinib_30min_R1 2 VGVNGFGR 8 0 P04406 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 119.56 0.015915000000000002 237830000.0 169099.0 150677.0 180295.0 183085.0 205715.0 201457.0 194189.0 127693.0 171198.0 143489.0 False True 166687.6172510416 150328.11666406758 165471.8410588266 196549.68165365548 193615.24815125114 192841.15372920423 204243.1562459256 133626.08294621477 151915.87844513837 168290.88246292554 0.9904732497184622 0.8932635830534957 0.983248995056402 1.1679164003252247 1.150479724853214 1.1458799841499858 1.2136317384331283 0.7940185528211998 0.9026982105141995 1.0 17.360597491973152 -7.769918594385003 24.9999284824524 0.8862687951794398 1.0759796089961027 0.3800778274622577 0.1043298514606501 215.87222279931208 636461.3031127161 0.0624493386893389 0.030765171194752642 1.69856200678632e-08 7.769918594385003 0.18971081381666288 VGWEQLLTTIAR ddPTM_PC-9_Lapatinib_30min_R1 2 VGWEQLLTTIAR 12 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144;P12814-4;P12814-3;P12814;P12814-2;H9KV75;H7C5W8;H0YJ11;H0YJW3 O43707;P12814-4 ACTN4;ACTN1 Alpha-actinin-4;Alpha-actinin-1 0 ; 266.26 2.5207e-50 40821000.0 58294.0 63200.0 56799.0 57927.0 65881.0 67827.0 63074.0 38729.0 61969.0 50920.0 False True 57462.71687018963 63053.66428299642 52129.205470480454 62187.14481880725 62006.00910702953 64926.19732245946 66339.66309654775 40528.49072716564 54989.3986575006 59721.45415336494 0.9621787962936257 1.055795863929809 0.8728723405932555 1.0412865142082846 1.0382535051440283 1.0871503087605456 1.1108179470343644 0.6786253165083407 0.920764563372613 1.0 15.865961673526714 -7.743210566629766 24.999978431717697 0.8497710731455249 1.023093238409684 0.3468799846744277 0.09828830240620644 231.03891529735526 316860.02263849846 0.045354136331064096 0.026120445765593185 1.8062981343826395e-08 7.743210566629766 0.1733221652641591 VHAPGLNLS(ph)GVGGK ddPTM_PC-9_AZD4547_30min_R2 2 VHAPGLNLSGVGGK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VHAPGLNLS(1)GVGGK;VHAPGLNLS(1)GVGGK 103.04 0.00074338 23421000.0 162154.0 200637.0 266170.0 325150.0 291350.0 277610.0 254840.0 343040.0 281380.0 318660.0 True False 213715.5989872738 265488.9865796209 262640.41188761155 250191.691017423 250901.0815670722 260251.00281458453 277520.2663095047 290031.0502749946 296253.17235134495 307503.8103925548 0.6950014658824801 0.8633681197013514 0.8541045769557415 0.8136214334971394 0.815928366047808 0.8463342372322215 0.9024937478180398 0.9431787199799093 0.9634130125839825 1.0 18.230244761963107 -7.592833405583906 0.7820015002162823 0.9998600082640118 0.8056062354989879 0.7433632905429661 0.042269367490108456 0.3412042423350087 0.3910272267855736 0.03770638176175515 0.018729081533231506 2.5536807011492494e-08 7.592833405583906 -0.19425377276502387 VHAPGLNLS(ph)GVGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VHAPGLNLSGVGGK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VHAPGLNLS(1)GVGGK;VHAPGLNLS(1)GVGGK 129.05 1.3469000000000001e-05 17044700.0 201748.0 175445.0 206242.0 228129.0 257710.0 209214.0 211088.0 218337.0 185666.0 152956.0 True False 235899.95169536726 192862.02012438883 211159.59145714075 215347.67173419736 207213.57548671443 198242.44953980192 191092.2164952239 212605.88509717377 188381.01400443705 180685.71200097012 1.3055816593516851 1.0673894354377802 1.168656830242377 1.191835642948022 1.1468177156453958 1.0971672709723586 1.0575945069425186 1.1766613017859002 1.0425894328790404 1.0 17.463122901832826 -1.5228787538614807 0.06249179655118942 0.8220228757013093 1.7793276296232152 0.48242482188735514 0.061543333199559035 297.7276059040528 1.3915216824225753 4.167610770864015 25.69667582287653 0.029999999407235634 1.5228787538614807 0.957304753921906 VHAPGLNLS(ph)GVGGK ddPTM_PC-9_Lapatinib_30min_R1 2 VHAPGLNLSGVGGK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VHAPGLNLS(1)GVGGK;VHAPGLNLS(1)GVGGK 119.04 6.0555e-05 17101000.0 350950.0 301760.0 335620.0 253310.0 236670.0 249140.0 221230.0 220430.0 261230.0 210351.0 True False 345945.3886436531 301061.29326007963 308026.61913066544 271939.2624173881 222749.53591112283 238484.8629737062 232684.20691329645 230671.9825192785 231807.52652614858 246709.89007491144 1.402235591522535 1.220304922387444 1.248537782725839 1.1022633196213414 0.9028804473281827 0.9666611375056436 0.9431490843056344 0.9349928470611245 0.9395955973056537 1.0 17.912456025810684 -5.860589441491151 1.6848736473138868 0.9427396551273214 1.3123101201468859 0.9093036871598187 0.04861303961254957 0.09626679289023095 0.5570674151269487 0.015212889263559215 0.029193273714870988 1.378512023807412e-06 5.860589441491151 0.3695704650195645 VHAYFAPVT(ph)PPPSVGGSR ddPTM_PC-9_AZD4547_30min_R2 1 VHAYFAPVTPPPSVGGSR 18 0 J3KTA1;Q96IG2-2;Q96IG2 J3KTA1 FBXL20 F-box/LRR-repeat protein 20 1 VHAYFAPVT(1)PPPSVGGSR 80.142 0.0077801 5300300.0 17001.0 26086.0 32458.0 26146.0 26329.0 22454.0 18509.0 24740.0 24870.0 21774.0 True False 22406.96435723221 34517.789360466864 32027.585712319564 20118.443651673195 22673.672821621578 21049.94783040483 20156.265143315886 20917.00146864317 26184.577426888696 21011.6988874898 1.0664042197260468 1.6427890740914093 1.5242739715534632 0.9574877195509192 1.0790975514655459 1.0018203641276149 0.9592877401891936 0.9954931098454389 1.246190399315059 1.0 14.358905194462256 -5.76282265964816 24.999999326688812 1.031409533982146 1.4343191311942285 0.5436047842361915 0.15784046930659718 25.05190105330309 452778.7329659396 0.042796939747673804 0.06759772995598148 1.726542766698152e-06 5.76282265964816 0.4029095972120824 VHAYFAPVT(ph)PPPSVGGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VHAYFAPVTPPPSVGGSR 18 0 J3KTA1;Q96IG2-2;Q96IG2 J3KTA1 FBXL20 F-box/LRR-repeat protein 20 1 VHAYFAPVT(0.998)PPPS(0.001)VGGS(0.001)R 99.059 0.0014105 3911800.0 20090.0 18758.0 14977.0 17624.0 24394.0 21754.0 21319.0 17758.0 16998.0 16368.0 True False 23490.84020441309 20620.17027269677 15334.108480588802 16636.584417778922 19614.170813794222 20613.18194427169 19299.509983806158 17291.871316156277 17246.563592943356 19335.3888309833 1.2149142905660648 1.0664471479184696 0.7930592249594284 0.8604215081064326 1.0144182248026066 1.0660857210815868 0.9981443948455979 0.894312054818755 0.891968801025983 1.0 14.238956156584127 -4.971775490130486 4.526876904032774 0.9413047808696112 1.1958537402991698 0.5472118855058217 0.0785647282494505 0.1595574485181497 7.87051745169048 0.022055882875965615 0.09282535108812583 1.0671476439223306e-05 4.971775490130486 0.2545489594295586 VHELNEEIGK ddPTM_PC-9_AZD4547_30min_R2 1 VHELNEEIGK 10 0 Q9NQ29-3;Q9NQ29;B8ZZ10;A8MYV2;Q9NQ29-2;B8ZZ09;Q96HJ9-2;A0A0A6YYJ8;Q9Y383-3;Q9Y383-2;Q9Y383 Q9NQ29-3;Q96HJ9-2 LUC7L;LUC7L2 Putative RNA-binding protein Luc7-like 1;Putative RNA-binding protein Luc7-like 2 0 113.93 0.0010494999999999999 2089500.0 18829.0 20937.0 29882.0 25475.0 29313.0 23372.0 21801.0 26049.0 22172.0 27169.0 False True 24816.230332470168 27704.475804649792 29485.745155448043 19602.132334826547 25243.3959292109 21910.545145284646 23741.24676586686 22023.725596470736 23343.966654964886 26217.82157959999 0.9465405147077363 1.0567039569071812 1.1246451222473348 0.7476644188500737 0.9628334624434515 0.8357118869987725 0.90553849768891 0.8400288151173984 0.8903854419822873 1.0 14.678260197570184 -5.750471870239655 24.99999812144495 0.8787750003763789 1.044037265654743 0.4730745959234455 0.07702068776123207 171.81557543192997 391643.1338433232 0.019677128941533815 0.033666953867935875 1.7763483207158061e-06 5.750471870239655 0.16526226527836407 VHELNEEIGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VHELNEEIGK 10 0 Q9NQ29-3;Q9NQ29;B8ZZ10;A8MYV2;Q9NQ29-2;B8ZZ09;Q96HJ9-2;A0A0A6YYJ8;Q9Y383-3;Q9Y383-2;Q9Y383 Q9NQ29-3;Q96HJ9-2 LUC7L;LUC7L2 Putative RNA-binding protein Luc7-like 1;Putative RNA-binding protein Luc7-like 2 0 125.75 0.00030984 3456400.0 23283.0 23490.0 24251.0 30096.0 28847.0 27147.0 25035.0 26889.0 27533.0 22897.0 False True 27224.352039788428 25821.931959998226 24829.23581242964 28409.818692548495 23194.63742992219 25723.36353043777 22663.503562295937 26183.192241250483 27935.618037681452 27048.044847447723 1.0065182971018825 0.9546690751821496 0.9179678587664183 1.0503464798576474 0.8575347150132685 0.9510248772330415 0.8378980325609185 0.9680253189805381 1.0328146893884451 1.0 14.72323669297918 -8.006302283786178 24.94506728903445 1.011078252847887 0.938048016592323 0.20816545606140313 0.05937558993068383 415.52591184094797 1644682.5685755245 0.033938556910414565 0.0154033203153015 9.85593240290518e-09 8.006302283786178 -0.07303023625556404 VHELNEEIGK ddPTM_PC-9_Lapatinib_30min_R1 3 VHELNEEIGK 10 0 Q9NQ29-3;Q9NQ29;B8ZZ10;A8MYV2;Q9NQ29-2;B8ZZ09;Q96HJ9-2;A0A0A6YYJ8;Q9Y383-3;Q9Y383-2;Q9Y383 Q9NQ29-3;Q96HJ9-2 LUC7L;LUC7L2 Putative RNA-binding protein Luc7-like 1;Putative RNA-binding protein Luc7-like 2 0 ;; 141.88 9.256200000000001e-05 10262100.0 121739.0 107396.0 111323.0 104149.0 116002.0 107565.0 105891.0 110255.0 112659.0 108476.0 False True 120002.9795358019 107147.33116039044 102170.45265920679 111808.46489087935 109178.99042870682 102964.69569626197 111373.51785135778 115377.84980566651 99970.15706813656 127225.93206481547 0.94322735615461 0.8421815381616072 0.803063109863136 0.8788182022036068 0.8581504466643278 0.8093058861915543 0.8753995042034226 0.9068736847365918 0.7857687143310264 1.0 16.95703323506111 -11.679177453770189 2.48842987145471 1.3542320824788872 0.8553575795998103 0.4685276922273912 0.046050597983379876 6159070.190921283 1341632.1358594852 12374617.22027688 0.0114269420155171 2.0932569712515747e-12 11.679177453770189 -0.49887450287907686 VHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 VHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPR 40 2 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 VHEPPREDAAPTKPAPPAPPPPQNLQPES(0.002)DAPQQPGS(0.499)S(0.499)PR 58.562 2.4046e-05 20823000.0 50063.0 54509.0 87815.0 108640.0 101920.0 87507.0 62125.0 91637.0 68485.0 81064.0 True False 65981.99262491135 72127.9682684079 86650.51572269823 83594.7264712681 87770.16726725952 82035.17345663291 67654.004647928 77476.60725877338 72104.97728510146 78225.97403396132 0.8434793358567281 0.9220462788624912 1.1076949413896648 1.0686313274280992 1.1220079820182827 1.0486948161363623 0.8648534643820023 0.9904204864887639 0.9217523741385122 1.0 16.255360096904646 -10.189821590206165 11.854229348379626 0.9999916737701725 0.993914479907398 0.0 0.09359996016168902 0.0 0.0 0.09824640358119638 0.023828252900137292 6.459195206890192e-11 10.189821590206165 -0.006077193862774499 VHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPR 40 2 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 VHEPPREDAAPTKPAPPAPPPPQNLQPES(0.13)DAPQQPGS(0.479)S(0.391)PR 52.784 0.00025839999999999994 22791000.0 17563.0 16376.0 19913.0 20809.0 28336.0 24013.0 23349.0 22747.0 19838.0 11816.0 True False 20536.069014938115 18001.70105478634 20387.80144047304 19643.139193688246 22783.764211677986 22753.716007529456 21137.2136878789 22149.91535243873 20128.093220191233 13958.147264595465 1.4712603775880344 1.2896912973863845 1.460638081401122 1.4072884331513422 1.6322914337971275 1.630138697937638 1.5143280327392001 1.5868807609317537 1.442031871324764 1.0 13.768819837603587 -8.566568261904527 20.510532684832338 0.9999999985065346 1.4981512585104821 0.6944869078184587 0.09868680284968655 1413.6633954970705 663659.8091639536 0.10595272334705447 0.027356875523455983 2.712887210162741e-09 8.566568261904527 0.4981512600039475 VHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 VHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPR 40 2 Q9Y618;Q9Y618-4;C9J0Q5;Q9Y618-5;A0A384DVL6;C9JE98;C9J7T7;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 VHEPPREDAAPTKPAPPAPPPPQNLQPES(0.008)DAPQQPGS(0.73)S(0.262)PR 58.635 2.3736999999999997e-05 16042000.0 50737.0 38203.0 42005.0 39998.0 43536.0 43846.0 43040.0 42751.0 46585.0 42633.0 True False 50013.481075973716 38114.54330068532 38551.511043989005 42939.58634941656 40975.29807506924 41970.808790018134 45268.40060366262 44737.36753019852 41338.10673820243 50002.05724509832 1.0002284672172466 0.7622595029211857 0.7709984982221545 0.8587563935407059 0.8194722443962248 0.8393816395250919 0.9053307623277893 0.8947105378266031 0.8267281191166346 1.0 15.609699832761699 -7.2369481181933235 7.44292586685726 0.8979488515460182 0.8346456033473348 0.15144707815229397 0.07286447071938665 0.414284472071232 101.32178608994936 0.027690410708587986 0.020927373763435793 5.794979204317004e-08 7.2369481181933235 -0.06330324819868338 VHFTAER ddPTM_PC-9_AZD4547_30min_R2 1 VHFTAER 7 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 90.777 0.013178 1217000.0 704.32 904.64 2242.8 6133.0 4415.8 4749.3 1929.2 4695.8 2137.7 3599.2 False True 928.2791092339157 1197.047188800611 2213.059006580514 4719.131603905445 3802.742392256319 4452.3255202165155 2100.8950626443893 3970.172008749175 2250.6944577989543 3473.193103511219 0.2672696511735767 0.3446532205740182 0.637182828775983 1.3587299822559957 1.0948836643755693 1.2819113097153867 0.6048886428227941 1.1430899147921076 0.6480188088372105 1.0 11.76204690895345 -5.517594689760035 4.347208164023023 1.0227761638730588 0.33213848288322967 0.611555963969505 0.2292871926474372 0.1294501350114208 6.00252034826605 0.06263193973651734 0.12435529666061382 3.0367239191105523e-06 5.517594689760035 -0.6906376809898291 VHFTAER ddPTM_PC-9_Lapatinib_30min_R1 1 VHFTAER 7 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 69.176 0.039637 2443200.0 1097.2 2718.5 3593.5 3051.1 2838.8 3377.7 2615.6 3234.0 3117.1 809.49 False True 1081.5537267981624 2712.2054802741422 3298.056301311141 3275.4880721712293 2671.827365295539 3233.2436448032695 2751.02296977091 3384.2634462974434 2766.0193734818226 949.4092679223752 1.1391859794722285 2.8567295179341934 3.4737983004193653 3.4500274885025 2.8141997930380334 3.4055320018928055 2.8976154570210464 3.5645991256261307 2.913410967153078 1.0 9.890886322879323 -4.767343372343786 4.405778033753641 3.0666316600243237 0.9795609565954779 0.35312214151684274 0.7116201695264934 0.19281222720599134 8.01859424037892 0.16085131492229407 1.277549358712852 1.70866383601269e-05 4.767343372343786 -2.0870707034288456 VHGLPT(ph)TSPSGMNMAELAQQVVK ddPTM_PC-9_AZD4547_30min_R2 2 VHGLPTTSPSGMNMAELAQQVVK 23 0 B1AKB5;B0QYS6;B0QYS7;P19484-2;P19484 B1AKB5 TFEB Transcription factor EB 1 VHGLPT(0.276)T(0.241)S(0.241)PS(0.241)GMNMAELAQQVVK;VHGLPT(0.434)T(0.434)S(0.095)PS(0.037)GMNMAELAQQVVK 84.68 7.4491e-05 8726500.0 46473.0 44681.0 73823.0 99755.0 96047.0 75678.0 64444.0 78015.0 69688.0 84534.0 True False 61250.44730155011 59123.25946542281 72844.0587849086 76758.02594938656 82712.53194190026 70945.84269659648 70179.3911554298 65959.57435635412 73371.56540912829 81574.49039014714 0.750852956709959 0.7247763263080578 0.8929759589856655 0.9409562423531569 1.0139509489585556 0.8697062323930321 0.8603105066275267 0.8085808938663128 0.899442522511797 1.0 16.31583044913102 -5.2842428211547805 6.560108661866561 0.9057806190120307 0.7373583086842658 0.5756729830116445 0.059283036202932786 0.12161392435728681 22.181668432577844 0.016745361083677968 0.03714792359259823 5.197053395219825e-06 5.2842428211547805 -0.1684223103277649 VHGLPTT(ph)SPSGMNMAELAQQVVK ddPTM_PC-9_AZD4547_30min_R2 1 VHGLPTTSPSGMNMAELAQQVVK 23 0 B1AKB5;B0QYS6;B0QYS7;P19484-2;P19484 B1AKB5 TFEB Transcription factor EB 1 VHGLPT(0.115)T(0.647)S(0.11)PS(0.128)GMNMAELAQQVVK 83.06299999999999 7.3343e-05 3515600.0 23124.0 18891.0 29783.0 44507.0 40740.0 32140.0 30408.0 30680.0 26260.0 35831.0 True False 30476.950990920417 24997.146316360482 29388.05796013351 34246.598776295374 35083.95422358856 30130.2807192131 33114.25309189849 25939.11095626403 27648.049989147483 34576.56759610758 0.8814336734323891 0.722950485090212 0.8499414488858008 0.9904568659426636 1.0146742913700346 0.8714075113287122 0.9577079332659466 0.7501933465247747 0.7996181203440196 1.0 15.07750703980052 -5.524650967320027 24.98431401192558 0.9071752220541016 0.7982555419010817 0.19924421938763248 0.08929865512178141 88.3028659690202 1244865.7054220994 0.025640954802015302 0.044819479133080216 2.987782867979912e-06 5.524650967320027 -0.1089196801530199 VHGS(ph)PLELK ddPTM_PC-9_AZD4547_30min_R2 2 VHGSPLELK 9 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 VHGS(1)PLELK;VHGS(1)PLELK 113.38 0.0011930999999999999 9453800.0 75044.0 94907.0 72537.0 67070.0 63448.0 79697.0 72089.0 82017.0 77308.0 64675.0 True False 98906.43098783202 125583.83174246062 71575.11198516608 51608.047721170384 54639.340392200495 74713.53399126099 78504.7813451024 69343.15721316531 81394.3430525899 62410.74793553791 1.5847659939917615 2.0122148171044545 1.1468395164738892 0.8269096177869028 0.8754796601482127 1.197126079444365 1.2578727854084926 1.111077170310275 1.3041718893780851 1.0 15.929506880721231 -5.313580598683931 7.405431424990242 1.0850366676482055 1.7972388721878902 0.7258594284279603 0.1742187672555982 0.123863664217534 15.614990382228205 0.047878856564914765 0.10116587262116193 4.8575737313028215e-06 5.313580598683931 0.7122022045396847 VHGS(ph)PLELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VHGSPLELK 9 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 VHGS(1)PLELK;VHGS(1)PLELK 102.05 0.0018716999999999998 8157400.0 116442.0 127702.0 99679.0 94126.0 102845.0 69597.0 93227.0 60081.0 62028.0 63104.0 True False 136153.33076566766 140379.4106068838 102055.72539471253 88852.42538060946 82693.26052900974 65947.21080148377 84395.8636549698 58503.937411081526 62935.042154552924 74544.25566901077 1.8264764943151583 1.8831687210104069 1.369062236637755 1.191941948889119 1.1093176769539688 0.8846719336000972 1.1321578423118455 0.7848215383737817 0.8442641433566023 1.0 16.185809563216708 -5.495664177927068 0.9164808512475388 0.921695860829566 2.0345414419041163 0.9122772121853215 0.10837735937651996 0.23703165529814352 0.30993745524334454 0.04213639656880122 0.2128022199478402 3.194006694551834e-06 5.495664177927068 1.1128455810745503 VHGS(ph)PLELK ddPTM_PC-9_Lapatinib_30min_R1 2 VHGSPLELK 9 0 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;D6RD46;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 VHGS(1)PLELK;VHGS(1)PLELK 100.09 0.0022288 9343400.0 74449.0 136530.0 132448.0 114375.0 131128.0 121820.0 126933.0 117766.0 110730.0 103895.0 True False 73387.34360772542 136213.8731733781 121558.63670406517 122786.5190438151 123415.30884756696 116610.0425762899 133504.9696520609 123237.83828591977 98258.42136140709 121853.11231861443 0.6022607236804626 1.1178530493108292 0.9975833558212344 1.007660097534153 1.0128203252196613 0.9569722131625554 1.0956221561496098 1.011363894946603 0.8063677610834157 1.0 16.894783574651022 -4.751212630217292 24.999652643823804 1.0031484547534035 0.6022599000817008 0.6946298310884602 0.07923745841986453 238.02082109204733 581811.2524469049 0.019285693125659427 0.26178847139807426 1.773321051803708e-05 4.751212630217292 -0.4008885546717027 VHHEPQLSDK ddPTM_PC-9_AZD4547_30min_R2 3 VHHEPQLSDK 10 0 O43852;O43852-3;O43852-5;O43852-2;O43852-4;O43852-9;O43852-13;O43852-14;O43852-11;O43852-10;O43852-6;O43852-12;O43852-7;O43852-8 O43852 CALU Calumenin 0 ;; 70.1 0.015419 9235400.0 43394.0 44073.3 58248.0 61181.0 53366.0 60072.0 52131.0 68252.0 50657.4 55491.0 False True 57192.389348728626 58319.132324644015 57475.59346143289 47076.665687027365 45957.05206421275 56315.68834363937 56770.55800887134 57705.221674932705 53335.046744868174 53548.27698014588 1.0680528408025878 1.089094469767291 1.0733416031806802 0.8791443598546038 0.858235869685448 1.0516806799314862 1.060175251388951 1.0776298497209928 0.9960179813935607 1.0 15.708552533755773 -5.568652818246439 24.999922369032845 0.9911099175317107 1.079235538238191 0.2585109923176073 0.06814815396248386 190.63560647821558 104116.5203663233 0.021171567594384114 0.036670247856586013 2.6998969094893757e-06 5.568652818246439 0.08812562070648033 VHHEPQLSDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VHHEPQLSDK 10 0 O43852;O43852-3;O43852-5;O43852-2;O43852-4;O43852-9;O43852-13;O43852-14;O43852-11;O43852-10;O43852-6;O43852-12;O43852-7;O43852-8 O43852 CALU Calumenin 0 ; 70.1 0.015419 5359100.0 31182.8 40995.0 40775.0 46029.0 43643.0 42738.0 49956.0 31573.2 39635.0 34297.0 False True 36461.43215162631 45064.7126734835 41747.23064004862 43450.144358031415 35091.46744389691 40496.74404405089 45223.80602988041 30744.436954570632 40214.58689294685 40514.77460509741 0.899953967583936 1.1123031810675217 1.0304199158693121 1.072451834708336 0.8661400140057015 0.9995549633134513 1.116229979573687 0.7588450695885764 0.99259066068918 1.0 15.306160494028068 -6.236322116730948 24.868475939491052 0.9537355839220658 1.0348649827574103 0.1093479537501999 0.10170518647960396 1575.135470933279 1559533.3092711298 0.029706746840418387 0.038336070472855394 5.803338235716199e-07 6.236322116730948 0.08112939883534454 VHHEPQLSDK ddPTM_PC-9_Lapatinib_30min_R1 2 VHHEPQLSDK 10 0 O43852;O43852-3;O43852-5;O43852-2;O43852-4;O43852-9;O43852-13;O43852-14;O43852-11;O43852-10;O43852-6;O43852-12;O43852-7;O43852-8 O43852 CALU Calumenin 0 ; 61.65 0.026473000000000003 6356200.0 25696.0 33754.0 39231.0 34590.0 39413.0 38506.0 40107.0 41173.0 40215.0 34080.0 False True 25329.570327930713 33675.844686839584 36005.57861603934 37133.86398885741 37094.80482893937 36859.18814187013 42183.544214941816 43086.04788942629 35685.56321727619 39970.68259125445 0.6337037219742852 0.842513625078993 0.9007996932210842 0.9290275167075147 0.9280503214887723 0.9221555838512222 1.0553621174378327 1.0779412583475239 0.8927934401871875 1.0 15.286654589851194 -4.049843225873013 0.6483673289301755 0.9917419180559949 3.8543414364891445e-20 0.7821974793240627 0.05499592026359444 3.6560474436186112 0.5810983724683512 0.025119294730250732 3.330098667438247 8.915727251146874e-05 4.049843225873013 -0.9917419180559949 VHIDIGADGR ddPTM_PC-9_AZD4547_30min_R2 2 VHIDIGADGR 10 0 P31942;P31942-2;P31942-3;P31942-4;P31942-5;P31942-6 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 0 ; 167.93 9.8454e-05 20313400.0 106339.0 98264.0 142013.0 199496.0 167674.0 141203.0 129926.0 159258.0 114541.0 126461.0 False True 140152.59001139458 130025.9163427477 140129.81483035427 153505.2793824753 144395.3593639173 132373.55408820952 141489.16229998667 134648.33548476858 120595.40341991399 122033.63888173267 1.1484750540563793 1.0654924128646255 1.1482884237038877 1.2578931578959387 1.1832422657154082 1.0847300408414244 1.159427544704367 1.1033706502455547 0.988214434355985 1.0 16.89691935958927 -8.137815089515087 2.933654118600173 0.9911787682348129 1.1491213541666472 0.6042813352737447 0.049559626670671125 0.20248657573418705 3.119767217207426 0.045388369749499044 0.014427039880286454 7.280897388675515e-09 8.137815089515087 0.1579425859318343 VHIDIGADGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VHIDIGADGR 10 0 P31942;P31942-2;P31942-3;P31942-4;P31942-5;P31942-6 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 0 ;; 117.71 0.00078429 8501600.0 62525.4 60717.0 89510.0 83859.0 89126.0 81090.0 75620.0 75862.0 72026.0 61527.0 False True 73109.71528705861 66744.58249532622 91644.25786856526 79160.65210454623 71662.40009634444 76837.49764921352 68456.72615861082 73870.7028824332 73079.24399019533 72681.35805253597 1.0058936327828796 0.9183177679079896 1.2609045885235441 1.0891465738343367 0.9859804772022146 1.0571830206264636 0.9418746153467376 1.0163638223303082 1.0054743877704069 1.0 16.149297756157175 -6.262314068922536 24.943412055352876 1.001802520417237 1.0715721471512911 0.13262205653280057 0.0843170570536224 173.32411751475857 4942657.932635813 0.026865596842351992 0.032265904430816804 5.466205201342612e-07 6.262314068922536 0.06976962673405418 VHIDIGADGR ddPTM_PC-9_Lapatinib_30min_R1 1 VHIDIGADGR 10 0 P31942;P31942-2;P31942-3;P31942-4;P31942-5;P31942-6 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 0 94.363 0.005314 2171500.0 14300.0 13970.0 16336.0 11544.0 15276.0 13988.0 12991.0 14585.0 13364.0 12237.0 False True 14096.079377701175 13937.653323314242 14992.917138783585 12392.984269655097 14377.49571377153 13389.76584762061 13663.610414548823 15262.672345160245 11858.805590841193 14352.14914522244 0.982158089012996 0.9711195990430342 1.0446461353681267 0.863493275066786 1.0017660469029843 0.9329450044126535 0.9520253918972951 1.0634415926649494 0.8262738542393678 1.0 13.808979167251673 -5.6998763134215995 24.999998102711384 0.9529120067643698 0.996488698012886 0.10571458128360722 0.06664941000608182 180.55970795262294 73320.62766027653 0.017033630592436327 0.0295031011852879 1.9958306443507273e-06 5.6998763134215995 0.04357669124851615 VHIEIGPDGR ddPTM_PC-9_AZD4547_30min_R2 3 VHIEIGPDGR 10 0 P31943;G8JLB6;E9PCY7;P55795;H0YB39;H0YBD7;H0YBG7;P52597 P31943;P52597 HNRNPH1;HNRNPH2;HNRNPF Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;Heterogeneous nuclear ribonucleoprotein H2;Heterogeneous nuclear ribonucleoprotein F;Heterogeneous nuclear ribonucleoprotein F, N-terminally processed 0 ;; 160.53 0.00011316 60308000.0 124776.0 124457.0 172943.0 229953.0 189867.0 169131.0 148167.0 180544.0 151246.0 161862.0 False True 164452.1724979714 164685.2913607156 170649.66282105105 176940.88858843458 163507.24439298236 158555.21183326808 161353.57596248726 152645.07328838808 159240.5547851713 156195.2606469582 1.052862755353864 1.054355238939977 1.092540593832508 1.1328185493948302 1.0468130960935567 1.015108980749704 1.0330247876546537 0.9772708381556182 1.019496712804214 1.0 17.252991153621814 -6.598825164948215 3.58363614634114 1.0090226636544002 1.0826140895367866 0.6598256971357239 0.024990027913550015 0.15515001212693938 3.9780105178186242 0.009173868666609315 0.00928312441411255 2.518690679505913e-07 6.598825164948215 0.07359142588238643 VHIEIGPDGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 VHIEIGPDGR 10 0 P31943;G8JLB6;E9PCY7;P55795;H0YB39;H0YBD7;H0YBG7;P52597 P31943;P52597 HNRNPH1;HNRNPH2;HNRNPF Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;Heterogeneous nuclear ribonucleoprotein H2;Heterogeneous nuclear ribonucleoprotein F;Heterogeneous nuclear ribonucleoprotein F, N-terminally processed 0 ;;;; 169.76 0.00012772 51564100.0 261821.0 271608.0 303466.0 312723.0 333252.0 288513.0 321811.0 310692.0 262191.0 216230.0 False True 306142.1240995346 298571.4472452625 310701.7803412135 295202.1441716447 267953.66286949837 273382.870381891 291326.73237012257 302536.6642053849 266025.04735835997 255430.78732426118 1.1985325939229752 1.1688937358449107 1.2163834422464805 1.1557030664314363 1.049026492367734 1.070281594656952 1.1405310041983805 1.1844173812192982 1.0414760497161593 1.0 17.9625728994114 -1.5228790990392171 0.04942553345066461 0.7575532301725875 1.8031162843606228 0.5389377543958234 0.048825427283667656 457.0569039664729 1.7126641818751254 8.61966931043033 36.6517765458662 0.029999975563212274 1.5228790990392171 1.0455630541880354 VHIEIGPDGR ddPTM_PC-9_Lapatinib_30min_R1 4 VHIEIGPDGR 10 0 P31943;G8JLB6;E9PCY7;P55795;H0YB39;H0YBD7;H0YBG7;P52597 P31943;P52597 HNRNPH1;HNRNPH2;HNRNPF Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;Heterogeneous nuclear ribonucleoprotein H2;Heterogeneous nuclear ribonucleoprotein F;Heterogeneous nuclear ribonucleoprotein F, N-terminally processed 0 ;;; 167.93 0.00033214 48994800.0 94289.0 119236.0 135380.0 104672.0 140419.0 131468.0 111892.0 117531.0 120594.0 106928.0 False True 92944.42156951509 118959.91636783772 124249.57898191267 112369.928055556 132159.83049437575 125845.42010687647 117685.22026823924 122991.91932801025 107011.43380888231 125410.36232739581 0.7411223430395228 0.9485652872709308 0.990744119353927 0.8960178885553611 1.0538190628088595 1.003469073618852 0.9384010865147703 0.9807157641960081 0.8532902052345458 1.0 16.936297033587152 -4.762707599012294 4.8443810399554925 0.9653785068236529 0.725712720642991 0.6013742374658675 0.054273181492722325 0.12189708067956835 7.124117865003368 0.013294574637060127 0.10033146471353482 1.7270002521947202e-05 4.762707599012294 -0.23966578618066192 VHIS(ph)GSVDGLDK ddPTM_PC-9_Lapatinib_30min_R1 1 VHISGSVDGLDK 12 0 J3KP75 J3KP75 PHACTR2 Phosphatase and actin regulator 1 VHIS(0.569)GS(0.431)VDGLDK 72.523 0.031429 0.0 17826.0 14811.0 34375.0 14911.0 29314.0 35261.0 20588.0 25305.0 41975.0 21167.0 True False 17571.79797111197 14776.706039485125 31548.82019133726 16007.604681637831 27589.80815354143 33752.96922740568 21653.945902142317 26480.76268044428 37247.33348365455 24825.68774674539 0.7078070968412791 0.5952183959706143 1.2708135425361284 0.6448000492448152 1.1113411412805034 1.359598556613226 0.8722395175127069 1.0666678381917485 1.500354546614227 1.0 14.59954606487914 -4.671690753324863 0.500157246383041 1.168081072987616 0.20587576786636988 0.32415562970072254 0.24107256151038425 6.047559512128599 1.0738366689271797 0.150550234954353 3.5155921984466447 2.1296549627625175e-05 4.671690753324863 -0.9622053051212462 VHISGS(ph)VDGLDK ddPTM_PC-9_AZD4547_30min_R2 2 VHISGSVDGLDK 12 0 J3KP75 J3KP75 PHACTR2 Phosphatase and actin regulator 1 VHIS(0.088)GS(0.912)VDGLDK;VHIS(0.03)GS(0.97)VDGLDK 102.65 0.0023143 2874800.0 28454.0 29727.0 86060.0 167647.0 126817.0 123194.0 63106.0 144044.0 83109.0 123342.0 True False 37501.78012003327 39335.6714068312 84918.788169395 128998.5742703303 109210.64857076184 115490.65970512548 68722.31174747925 121785.30960182853 87501.97206961365 119023.8341223827 0.3150779034850548 0.3304856686635172 0.7134603652750742 1.0838045608385576 0.9175527689560836 0.9703154041095303 0.5773827759305551 1.0232010294392502 0.7351634461686251 1.0 16.860890971727663 -5.365144388399984 3.3304535460060634 0.8926694608565552 0.31380854651227397 0.721700943572462 0.14144662526108143 0.12215620268511564 2.5198168760768196 0.037596918585924795 0.09092582773387169 4.31375635003335e-06 5.365144388399984 -0.5788609143442812 down VHLENMGSHDIVDGNHR ddPTM_PC-9_AZD4547_30min_R2 2 VHLENMGSHDIVDGNHR 17 0 A0A087WUZ3;Q01082;Q01082-2;F8W6C1;P11277-3;P11277;P11277-2;O15020-2;Q01082-3;A4QPE4;O15020 A0A087WUZ3;Q01082-3;A4QPE4 SPTBN1;SPTB;SPTBN2 Spectrin beta chain, non-erythrocytic 1;Spectrin beta chain, erythrocytic;Spectrin beta chain, non-erythrocytic 2 0 ; 62.055 0.006678699999999999 7050600.0 7928.5 9601.900000000001 9464.5 15818.199999999999 11146.1 8417.2 10204.3 11990.0 9882.2 14694.7 False True 10449.598076955219 12705.526399611546 9338.994546005555 12171.5583787538 9598.656410690737 7890.871153383967 11112.462931651538 10137.22100279029 10404.552917088851 14180.24302571858 0.7369124815423033 0.8960020203157059 0.6585919951489904 0.8583462467235824 0.6769035194447471 0.5564693876594614 0.7836581440456953 0.7148834462430934 0.733735867447279 1.0 13.791594637725929 -10.821451919163907 3.7907136339989065 1.0005806765769905 0.7350401201229226 0.42635711852637925 0.09219546159114426 18406921.46196877 8870316.37396562 85040.66522120275 0.022517084759316745 1.508509608721399e-11 10.821451919163907 -0.2655405564540678 VHLENMGSHDIVDGNHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VHLENMGSHDIVDGNHR 17 0 A0A087WUZ3;Q01082;Q01082-2;F8W6C1;P11277-3;P11277;P11277-2;O15020-2;Q01082-3;A4QPE4;O15020 A0A087WUZ3;Q01082-3;A4QPE4 SPTBN1;SPTB;SPTBN2 Spectrin beta chain, non-erythrocytic 1;Spectrin beta chain, erythrocytic;Spectrin beta chain, non-erythrocytic 2 0 ; 76.82 0.0017919000000000001 7331800.0 9202.0 12818.900000000001 15946.699999999999 16547.8 18176.3 16267.5 14598.3 15559.8 13168.6 14716.9 False True 10759.716852215484 14091.47567484126 16326.929806196524 15620.680414691438 14614.784494661293 15414.403662702935 13215.443341460548 15151.371736970857 13361.165862456399 17384.9574710837 0.6189095872171134 0.8105556598731708 0.9391411991287877 0.8985170335143601 0.840656902323171 0.8866517901088699 0.7601654110136145 0.8715219328072586 0.7685475149812675 1.0 14.085551917346558 -4.795404456556137 3.6123272980970142 0.8632775208678309 0.5951277036298945 0.5481743050564495 0.06830080810431875 0.19645795158532475 4.36828636800302 0.0166796812315931 0.13988065086870782 1.6017529902936244e-05 4.795404456556137 -0.2681498172379364 VHLENMGSHDIVDGNHR ddPTM_PC-9_Lapatinib_30min_R1 2 VHLENMGSHDIVDGNHR 17 0 A0A087WUZ3;Q01082;Q01082-2;F8W6C1;P11277-3;P11277;P11277-2;O15020-2;Q01082-3;A4QPE4;O15020 A0A087WUZ3;Q01082-3;A4QPE4 SPTBN1;SPTB;SPTBN2 Spectrin beta chain, non-erythrocytic 1;Spectrin beta chain, erythrocytic;Spectrin beta chain, non-erythrocytic 2 0 ; 85.473 0.00071632 5383500.0 12395.7 13164.400000000001 15386.7 12046.9 17044.5 17498.8 15672.8 18611.5 15331.3 13737.300000000001 False True 12218.93504490703 13133.918640618329 14121.664920379619 12932.869213280312 16041.976020776308 16750.41711569513 16484.260896400647 19476.25823462118 13604.527548253785 16111.774001198344 0.7583854542645784 0.815175202906984 0.8764810702613687 0.8026967863575051 0.9956678898042609 1.0396382865381109 1.0231189250280321 1.2088214639289625 0.8443842091654167 1.0 13.975827731559596 -6.336848840520745 3.711756274587331 1.0348735459227305 0.8166913730103014 0.571440851776263 0.08691441877657448 0.16737856923201067 4.464211042847583 0.026840532067734894 0.03129668384376311 4.6041679724489757e-07 6.336848840520745 -0.21818217291242914 VHNDAQSFDYDHDAFLGAEEAK ddPTM_PC-9_AZD4547_30min_R2 1 VHNDAQSFDYDHDAFLGAEEAK 22 0 O43852;O43852-3;O43852-5;O43852-2;O43852-4;O43852-9;O43852-13;O43852-14;O43852-11;O43852-10;O43852-6;O43852-12;O43852-7;O43852-8 O43852 CALU Calumenin 0 79.467 0.00024108 5667200.0 26438.0 28442.0 29444.0 33826.0 33678.0 44283.0 36294.0 42068.0 35153.0 33782.0 False True 34844.734055438224 37635.32028637576 29053.553321632153 26027.938306490367 29002.39102459537 41513.977009611524 39524.09568920562 35567.357226470536 37011.11581372814 32599.30246244055 1.0688797435339226 1.1544823797913308 0.8912323616465827 0.7984200992177236 0.8896629324511044 1.2734621256832737 1.2124215152990927 1.0910465727740537 1.1353345936272925 1.0 14.992553474535121 -6.751866621309735 24.99914706230091 1.1525164149421008 0.9584537358263008 0.3855109031958205 0.11447024247085048 226.34459412483776 591095.355279052 0.04194886506041785 0.04143468389657473 1.7706526702047694e-07 6.751866621309735 -0.1940626791158 VHNNS(ph)PDTSR ddPTM_PC-9_AZD4547_30min_R2 1 VHNNSPDTSR 10 0 Q9BRD0 Q9BRD0 BUD13 BUD13 homolog 1 VHNNS(0.56)PDT(0.342)S(0.098)R 98.902 0.004580399999999999 1337600.0 12220.0 11003.0 12848.0 19847.0 12892.0 11030.0 9635.6 13029.0 12275.0 14424.0 True False 16105.705808209976 14559.504574607712 12677.627125265926 15271.580783093328 11102.168332118401 10340.292356344753 10493.14973336941 11015.667426635084 12923.831440090828 13919.020150323915 1.1571005454601035 1.046015051157814 0.9108131885972519 1.09717355231632 0.7976257101589179 0.7428893876631194 0.7538712941029272 0.7914111271962441 0.9285015252880479 1.0 13.764770033694107 -6.267058601739636 24.944311352479854 0.8165534390464071 1.042152520601858 0.5508445143671452 0.09488738791346474 329.4499631699941 1462460.1246033162 0.029195980091917373 0.03403077050486428 5.406813609175978e-07 6.267058601739636 0.22559908155545094 VHNNS(ph)PDTSR ddPTM_PC-9_Lapatinib_30min_R1 1 VHNNSPDTSR 10 0 Q9BRD0 Q9BRD0 BUD13 BUD13 homolog 1 VHNNS(0.582)PDT(0.416)S(0.002)R 110.15 0.0017811 2787700.0 9167.2 10836.0 7411.5 7376.6 10704.0 7926.0 14954.0 13585.0 10446.0 11813.0 True False 9036.474046941408 10810.90990776185 6802.155079217343 7919.099771616238 10074.411764873694 7587.023456408425 15728.244949516045 14216.208694480762 9269.461478743424 13854.861310166925 0.6522240710060587 0.7802972303900745 0.4909580057813938 0.5715755354263324 0.7271391275119387 0.5476073189445023 1.1352148965918845 1.0260809095251406 0.6690403657769811 1.0 13.758104648785535 -7.251410360112414 24.94348384009365 0.9597574555298942 0.6308806188283566 0.5865392103592928 0.13542396095349288 486.6414898210732 1210342.997761248 0.052556404613287255 0.0402215652121483 5.605180983051683e-08 7.251410360112414 -0.32887683670153767 VHNNS(ph)PDTSRR ddPTM_PC-9_AZD4547_30min_R2 1 VHNNSPDTSRR 11 1 Q9BRD0 Q9BRD0 BUD13 BUD13 homolog 1 VHNNS(0.966)PDT(0.017)S(0.017)RR 69.258 0.016121 22791000.0 844.39 882.64 3115.8 3518.7 3302.3 2676.0 2923.7 1956.0 2555.9 3993.8 True False 1112.8884555969248 1167.9361190340592 3074.482456172446 2707.5180783730775 2843.832646847238 2508.669296969952 3183.9036360426094 1653.7451444084893 2690.9996560267323 3853.978277618109 0.28876355169410245 0.3030468868537276 0.7977425493100032 0.7025255160613973 0.7378953491675683 0.6509297967606594 0.8261342972618857 0.4291007954073266 0.6982394456280803 1.0 11.912132724780166 -5.253143916780072 24.49270042896537 0.7097960368768841 0.29590512351998133 0.6125943990486296 0.13741200116517016 299.9718559170978 885672.4041537589 0.033708172054828296 0.08594390971871588 5.582851591907995e-06 5.253143916780072 -0.41389091335690276 VHNNS(ph)PDTSRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VHNNSPDTSRR 11 1 Q9BRD0 Q9BRD0 BUD13 BUD13 homolog 1 VHNNS(0.516)PDT(0.242)S(0.242)RR;VHNNS(0.923)PDT(0.048)S(0.029)RR 100.18 0.0019498 19139400.0 5278.200000000001 6399.8 7335.200000000001 5422.1 7876.6 8531.1 6676.700000000001 6339.299999999999 8341.2 7317.3 True False 6171.695010798063 7035.129849195264 7510.098986900907 5118.317315685381 6333.236772646209 8083.7140978567695 6044.234640878025 6172.900092043556 8463.17426999995 8643.868566285075 0.7139968595624433 0.8138867215815143 0.8688353980986739 0.5921327096121164 0.7326854549071516 0.9351963227884843 0.6992511043554299 0.714136274135473 0.9790956682300894 1.0 13.07746142023175 -8.271201080450053 23.18944619904551 0.9895480286446934 0.7617450086430675 0.5077229445491256 0.09086017990979776 238.87039584086108 567432.3871414751 0.08475733350313697 0.023152060828974006 5.355486384854583e-09 8.271201080450053 -0.2278030200016259 VHNNS(ph)PDTSRR ddPTM_PC-9_Lapatinib_30min_R1 1 VHNNSPDTSRR 11 1 Q9BRD0 Q9BRD0 BUD13 BUD13 homolog 1 VHNNS(0.858)PDT(0.071)S(0.071)RR 56.648 0.036531 1871300.0 1890.7 0.0 407.72 0.0 617.97 639.76 0.0 660.54 844.89 554.17 True False 1863.7382712880844 0.0 374.1988354447136 0.0 581.6222195757659 612.3989561534005 0.0 691.231099819825 749.7295911138749 649.9575461148905 2.867476933575964 0.0 0.5757281189848173 0.0 0.8948618614437238 0.9422137796753098 0.0 1.063501922474239 1.1535054798507534 1.0 9.34420167713156 -4.75191328205811 24.99967257552055 0.6051793488372329 2.86748140358261 0.6971293601141308 0.44313743543561773 216.11913156181595 567129.134506885 0.11051538363651273 1.3927073070963056 1.7704624408927553e-05 4.75191328205811 2.262302054745377 VHNNSPDT(ph)SR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VHNNSPDTSR 10 0 Q9BRD0 Q9BRD0 BUD13 BUD13 homolog 1 VHNNS(0.293)PDT(0.671)S(0.036)R;VHNNS(0.033)PDT(0.483)S(0.483)R 101.56 0.0086964 3046900.0 7136.1 7639.3 9211.6 8834.3 14787.6 15031.2 8247.0 9839.3 13242.1 16820.2 True False 8344.100785600413 8397.679217625138 9431.239479187543 8339.342812187042 11890.075933674812 14242.93741108469 7465.784456890545 9581.028800600088 13435.740660908063 19869.56911137007 0.4199437209146938 0.42264022790608424 0.47465747376427275 0.41970426059289706 0.5984063301539282 0.7168216548256388 0.3757396255069446 0.48219610334264795 0.6761968810496075 1.0 14.278272966398234 -14.522878745229965 0.1810288077377088 3.0495515101738326 0.406236250462199 0.7164769209545383 0.0979809364233721 77.61360716601006 0.7463255016442224 57.04945009951546 0.32097945838449515 3.0000000003479597e-15 14.522878745229965 -2.643315259711634 VHNNSPDT(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 2 VHNNSPDTSR 10 0 Q9BRD0 Q9BRD0 BUD13 BUD13 homolog 1 VHNNS(0.312)PDT(0.653)S(0.035)R;VHNNS(0.019)PDT(0.876)S(0.105)R 93.839 0.015984 3891200.0 14692.4 12472.8 15614.400000000001 12805.099999999999 14894.8 13468.900000000001 21548.0 22634.7 18162.6 16278.0 True False 14482.883681743826 12443.91999792654 14330.644305327032 13746.829770561366 14018.71714830351 12892.86654453941 22663.65000482626 23686.39079403487 16116.936727343042 19091.630610928398 0.7585985700694188 0.6517997467855581 0.750624427916802 0.7200448222946672 0.7342860038512866 0.6753151057280198 1.1870987065847154 1.2406688185385457 0.8441885900577509 1.0 14.220652707741015 -7.255853505822015 24.979449563625323 1.0880447686065133 0.7149436721221433 0.7308612740481972 0.10462319088813293 220.10388532444546 984284.6320387003 0.03986773052940226 0.029996584524322453 5.5481282825910867e-08 7.255853505822015 -0.37310109648437007 VHNNSPDTS(ph)RR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VHNNSPDTSRR 11 1 Q9BRD0 Q9BRD0 BUD13 BUD13 homolog 1 VHNNS(0.075)PDT(0.335)S(0.59)RR 58.595 0.032737999999999996 16848000.0 1074.3 1197.5 3702.4 1182.7 5434.8 3286.7 3187.7 2894.1 2921.0 2933.3 True False 1256.157771607814 1316.3798859982078 3790.679257430191 1116.4371533651354 4369.88995403824 3114.339666095326 2885.7379790505615 2818.132941552422 2963.7140990109183 3465.0840700099775 0.3625186997567413 0.37989839767276334 1.0939645852284547 0.32219626733671736 1.2611209037781461 0.898777519728795 0.8328046075494648 0.8132942475892965 0.8553079922826763 1.0 11.758674640174686 -5.242755721398655 23.49617467361575 0.8700211236542023 0.37120819833523333 0.4440916103323157 0.22932810030648196 337.0449959600363 423856.33285014145 0.055648442367906774 0.14650997284608258 5.718001679733457e-06 5.242755721398655 -0.4988129253189689 VHNNSPDTS(ph)RR ddPTM_PC-9_Lapatinib_30min_R1 1 VHNNSPDTSRR 11 1 Q9BRD0 Q9BRD0 BUD13 BUD13 homolog 1 VHNNS(0.12)PDT(0.05)S(0.83)RR 75.483 0.0099363 20534000.0 2356.6 2180.5 3196.5 2402.6 2630.4 2936.8 2749.8 3685.4 2494.4 3346.1 True False 2322.9944518524885 2175.451186219521 2933.696108846824 2579.2952188386457 2475.685043565373 2811.199910015172 2892.171189125266 3856.6371382141633 2213.4544048035223 3924.4689266020077 0.5919258109310214 0.5543300831032775 0.7475396451633922 0.6572342059724047 0.6308331368822785 0.7163261991856928 0.7369586161125362 0.98271567703644 0.5640137420377123 1.0 11.938281721138653 -14.522878745232301 0.04677710289385147 2.334395516035347 2.4200627239959368e-11 0.47375050257714124 0.10966190383580904 522.1951526144197 1.8058730583439888 89.43378796551454 21.908541913567298 3.000000000331824e-15 14.522878745232301 -2.3343955160111465 VHPAVVIR ddPTM_PC-9_AZD4547_30min_R2 2 VHPAVVIR 8 0 P62829;C9JD32;J3KT29;J3KTJ3;J3QQT9 P62829 RPL23 60S ribosomal protein L23 0 ; 106.42 0.0032115000000000004 11868200.0 40273.0 43152.0 59478.0 75384.0 54365.0 54184.0 44436.0 61608.0 43354.0 58271.0 False True 53078.97626956143 57100.04011664749 58689.28285776518 58005.38347118988 46817.35815820796 50795.86591443194 48390.71791606161 52087.899211001124 45645.603931054815 56230.95002631203 0.9439459273713907 1.0154557248264309 1.0437185007598633 1.031556170472801 0.832590559759364 0.9033435481823291 0.8605708758862911 0.9263208106323607 0.8117523162901563 1.0 15.779076801079968 -6.252411424840711 24.953340657882855 0.8846984778323376 1.011657377254224 0.5323034634889912 0.054787012544999604 463.7665610464593 1281853.558072637 0.015364106789683302 0.019555464896711193 5.592275714333853e-07 6.252411424840711 0.12695889942188654 VHPAVVIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VHPAVVIR 8 0 P62829;C9JD32;J3KT29;J3KTJ3;J3QQT9 P62829 RPL23 60S ribosomal protein L23 0 ; 119.57 0.0028988000000000004 9218900.0 45058.0 49388.0 51001.0 48654.0 55409.0 42889.0 42219.0 50030.0 50550.0 40102.0 False True 52685.429463934495 54290.91424607889 52217.05726236958 45928.07411839629 44552.00420683463 40639.82533823059 38219.71068090963 48716.76551116672 51289.19811879559 47372.17515274265 1.1121598130983061 1.1460506947596996 1.10227273909221 0.9695158385763345 0.9404677759293316 0.8578838781878841 0.8067966175856898 1.0283835469679974 1.0826861539167927 1.0 15.531752296138999 -5.7628295559681915 3.2379641127340597 0.9427262452274867 1.1290664392076188 0.5036035113601225 0.07515887692882921 0.20642809768505907 4.485470018350917 0.0239213045292902 0.04127267433157743 1.7265153505152905e-06 5.7628295559681915 0.18634019398013213 VHPAVVIR ddPTM_PC-9_Lapatinib_30min_R1 1 VHPAVVIR 8 0 P62829;C9JD32;J3KT29;J3KTJ3;J3QQT9 P62829 RPL23 60S ribosomal protein L23 0 77.67399999999999 0.019478 6826000.0 22408.0 25192.0 25679.0 22544.0 23528.0 25594.0 26343.0 23651.0 24508.0 21493.0 False True 22088.45781087606 25133.669471791865 23567.77174380655 24201.960964579383 22144.12929782776 24499.404282528034 27706.911642711075 24749.911802220417 21747.650959318784 25208.03641237768 0.8762466639420656 0.9970498717405335 0.9349308830827565 0.9600890989151264 0.878455145635799 0.9718886422465776 1.099130102379033 0.9818262476829684 0.8627268940566996 1.0 14.621596122955923 -6.988784484421988 24.954082491455683 0.9917067687095511 0.934136424073861 0.1532334106427451 0.06279003627458522 421.1354215556061 937005.4931107543 0.022609568952563466 0.019923212327933325 1.0261610251043012e-07 6.988784484421988 -0.05757034463569011 VHPVS(ph)TMIK ddPTM_PC-9_Lapatinib_30min_R1 1 VHPVSTMIK 9 0 P00338-3;P00338;P00338-4 P00338-3 LDHA L-lactate dehydrogenase A chain 1 VHPVS(0.857)T(0.143)MIK 80.102 0.013599000000000002 0.0 53683.0 32330.0 20704.0 17230.0 25943.0 25875.0 21402.0 23820.0 21105.0 18203.0 True False 52917.470575743515 32255.141871349264 19001.797039751185 18497.151677595048 24417.083745900443 24768.386567571033 22510.090839209748 24926.76415918526 18727.93265449742 21349.364296027135 2.4786438529034247 1.510824464096646 0.8900404141441904 0.8664029252167077 1.1436913721334632 1.1601463268009407 1.0543682016517284 1.16756470185971 0.8772126605185367 1.0 14.381905491988972 -4.827558914942229 2.5693895646049096 1.03302627821105 2.7021126178903887 0.9379065403821479 0.1144057229912572 0.1019189506646507 0.9482798431666881 0.031649373753231055 0.35976929632883153 1.487445578481743e-05 4.827558914942229 1.6690863396793387 up VHPVSTMIK ddPTM_PC-9_AZD4547_30min_R2 1 VHPVSTMIK 9 0 P00338-3;P00338;P00338-4 P00338-3 LDHA L-lactate dehydrogenase A chain 0 76.17 0.016899 6365300.0 42944.0 44056.0 54068.0 63246.0 69233.0 66628.0 50811.0 68568.0 53535.0 51011.0 False True 56599.29870931006 58296.240437964 53351.02299259639 48665.61184095935 59621.19299856921 62461.74062724742 55333.080566050194 57972.39113589029 56364.750806131364 49225.12041654001 1.149805185449425 1.1842782698074623 1.0838170133692562 0.9886336778692233 1.2111944570995106 1.268899701995646 1.124082177916986 1.1776993259809503 1.1450403844455073 1.0 15.587107114861299 VHPVSTMIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VHPVSTMIK 9 0 P00338-3;P00338;P00338-4 P00338-3 LDHA L-lactate dehydrogenase A chain 0 83.647 0.0095085 16408000.0 63603.0 74818.0 78817.0 98745.0 94841.0 85121.0 86662.0 79269.0 68757.0 69357.0 False True 74369.73168348866 82245.4365850636 80696.29619513711 93212.63778560933 76257.58687181493 80657.10491304361 78452.74798145356 77188.27274244804 69762.44104953557 81930.87507029025 0.9077131376869254 1.0038393525579152 0.9849314574744384 1.1376985502185863 0.9307551860808507 0.9844531117706989 0.9575480295327894 0.9421145896003987 0.851479262118034 1.0 16.322119603293935 -7.28792185319279 1.3977857246379777 0.9238346984388223 1.0008357014013913 0.14571443668886552 0.0660060600088537 0.7566185006553856 2.874980037810447 0.04090739192381964 0.02343583008018516 5.153213629973719e-08 7.28792185319279 0.07700100296256907 VHPVSTMIK ddPTM_PC-9_Lapatinib_30min_R1 3 VHPVSTMIK 9 0 P00338-3;P00338;P00338-4 P00338-3 LDHA L-lactate dehydrogenase A chain 0 ;; 79.986 0.013128 61094000.0 326215.0 313797.0 342349.0 334217.0 348752.0 327365.0 324437.0 302288.0 319059.0 286958.0 False True 321563.1142794959 313070.42232613085 314202.3867253564 358796.4330952293 328239.09303281264 313364.3620750877 341234.7603775673 316333.4040365986 283123.2155797818 336558.30795250036 0.9554454805640371 0.9302115411464321 0.9335748941597986 1.0660751038297576 0.9752815047998701 0.9310849106102408 1.0138949249344544 0.9399066864848982 0.841230802775904 1.0 18.360496944522467 -9.715331553013378 6.733458959217892 0.9999999943111376 0.9573572684833532 0.054705149891584814 0.05578854279479045 9005961.849954935 1624274.289572392 0.05534647797011205 0.013836619449879347 1.926053946284454e-10 9.715331553013378 -0.04264272582778439 VHQLETQNR ddPTM_PC-9_Lapatinib_30min_R1 1 VHQLETQNR 9 0 Q16352 Q16352 INA Alpha-internexin 0 96.665 0.0031961 0.0 6860.6 5622.0 6830.2 6836.8 6229.0 7066.6 3897.4 6814.6 6639.9 6726.0 False True 6762.766585920044 5608.982604414648 6268.6473213344525 7339.601078896218 5862.622466685185 6764.377991049178 4099.188301875339 7131.231193920398 5892.044540753251 7888.580138168355 0.8572856543852373 0.7110256226308673 0.794648366567772 0.9304083815266146 0.7431784128450807 0.8574899250018642 0.5196357557479446 0.9039942637352981 0.746908117500765 1.0 12.945549938264577 -10.73723855538777 4.480303866487778 1.0000652616647732 0.7839442419948315 0.24978846981674152 0.11179261546707914 6.998923221397813e-05 1.2272781736121084e-05 0.1039556930598673 0.025205357213886653 1.8313082192827974e-11 10.73723855538777 -0.21612101966994168 VHS(ph)ENNACINFK ddPTM_PC-9_AZD4547_30min_R2 2 VHSENNACINFK 12 0 O94921;O94921-3;O94921-2;C9JWL6;F8WF96;C9IYJ9 O94921 CDK14 Cyclin-dependent kinase 14 1 VHS(1)ENNACINFK;VHS(1)ENNACINFK 135.02 3.3523000000000004e-05 11306300.0 65762.0 64221.0 67422.0 75776.0 66786.0 76564.0 67892.0 82654.0 66848.0 73611.0 True False 86672.94806542588 84979.18233989656 66527.94022724773 58307.013927529544 57513.91671027454 71776.44097653507 73934.25647576865 69881.72349996894 70381.44880710318 71033.90129544475 1.2201631402016775 1.196318670242403 0.936566048238632 0.8208336141502148 0.809668561931608 1.010453314087339 1.0408305770544788 0.983779888553725 0.9908149140559254 1.0 16.11622010216493 -5.250728307032734 7.177325962801247 0.9442723088485496 1.2098253634816714 0.6643566144592166 0.07362005848469565 0.09427270202973831 30.701344374997806 0.021768240351070535 0.05354164008596172 5.613990753127289e-06 5.250728307032734 0.26555305463312173 VHS(ph)ENNACINFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VHSENNACINFK 12 0 O94921;O94921-3;O94921-2;C9JWL6;F8WF96;C9IYJ9 O94921 CDK14 Cyclin-dependent kinase 14 1 VHS(1)ENNACINFK;VHS(1)ENNACINFK 82.171 0.0070298 13167000.0 40595.0 54791.0 47029.0 49110.0 50963.0 35921.0 49013.0 42977.0 33115.0 30171.0 True False 47466.93171220257 60230.28837889581 48150.34971847569 46358.52591676822 40977.16599095655 34037.23952469353 44370.133816609174 41848.89928789553 33599.24422757499 35640.76346649543 1.3318157944855609 1.689926997089052 1.350990973123796 1.3007164103077693 1.1497275031573797 0.9550087095269629 1.2449265812815682 1.1741863870911784 0.9427195424464014 1.0 15.12124062094154 -5.943310915001458 1.5777025469964816 1.0835702243181553 1.5068771019213167 0.6618686271764382 0.1246902852172972 0.2297241983122991 1.1604306288217034 0.041321001214189454 0.07487047713096602 1.1394337654673178e-06 5.943310915001458 0.42330687760316144 VHS(ph)ENNACINFK ddPTM_PC-9_Lapatinib_30min_R1 2 VHSENNACINFK 12 0 O94921;O94921-3;O94921-2;C9JWL6;F8WF96;C9IYJ9 O94921 CDK14 Cyclin-dependent kinase 14 1 VHS(1)ENNACINFK;VHS(1)ENNACINFK 121.21 0.0017432000000000003 10431000.0 35434.8 40250.4 38287.7 40296.5 42077.5 43939.2 34589.2 40088.2 29680.0 34811.1 True False 34929.493254053516 40157.202671777224 35139.83310079606 43260.039035183356 39602.58417754789 42060.02284327795 36380.0595297446 41950.84412116917 26337.125855744303 40828.15225212492 0.8555247133976187 0.9835664965633418 0.8606765470011489 1.059563968705732 0.9699822792124215 1.030172087718932 0.891053293450261 1.02749798379587 0.6450726864420756 1.0 15.31727665695781 -8.223140753064232 24.999689680364757 0.8225355705241486 0.9609708922840149 0.2171270611222701 0.10420177187507981 656.7915800804865 428726.30119007285 0.06443208647839806 0.024352068363379616 5.982176837359941e-09 8.223140753064232 0.13843532175986628 VHS(ph)PCPTSGSEK ddPTM_PC-9_AZD4547_30min_R2 3 VHSPCPTSGSEK 12 0 X6RLP6;Q96LT9-2;Q96LT9 X6RLP6 RNPC3 RNA-binding protein 40 1 VHS(0.809)PCPT(0.183)S(0.008)GSEK;VHS(1)PCPTSGSEK;VHS(0.932)PCPT(0.027)S(0.038)GS(0.002)EK 109.15 0.0013474000000000001 18446800.0 71623.2 88692.5 94131.0 88603.0 79649.0 109377.0 102970.0 122692.0 107044.0 95678.0 True False 94397.88774489246 117360.61614863177 92882.76143589731 68176.94725270399 68591.11119181666 102537.63889935822 112134.1305206785 103732.77058168015 112702.1273053428 92328.34234211656 1.022415060752497 1.2711223138151855 1.0060048635090444 0.7384184046116503 0.7429041771123415 1.11057597589494 1.2145147164580612 1.1235203400198093 1.220666638720021 1.0 16.49448596436313 -6.9773782976651715 24.811367656246443 1.151765518265731 0.9605809607073424 0.2541807399552032 0.15217670360974064 332.54508262389203 364732.37953158305 0.060279414213601765 0.053158313806539306 1.0534688593291783e-07 6.9773782976651715 -0.19118455755838848 VHS(ph)PCPTSGSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VHSPCPTSGSEK 12 0 X6RLP6;Q96LT9-2;Q96LT9 X6RLP6 RNPC3 RNA-binding protein 40 1 VHS(1)PCPTSGSEK;VHS(1)PCPTSGSEK;VHS(0.998)PCPT(0.001)S(0.001)GS(0.001)EK 87.447 0.0048588 18718000.0 233011.0 354201.0 285011.0 256285.0 290206.0 230551.0 265776.0 208352.0 207691.0 206242.0 True False 272455.1601229713 389363.7344471409 291806.74315023713 241926.1823371809 233342.21756120244 218460.4996981605 240599.77322839087 202882.98076719156 210728.08796223105 243632.04198922648 1.1183059416093528 1.5981630793225414 1.1977354898299502 0.9929982130506421 0.9577648968337299 0.8966821355452947 0.9875538999875488 0.832743423692041 0.864944061715616 1.0 17.894344360468395 -5.684686418666675 2.8205998142699698 0.9220907672480544 1.3663875417925644 0.6793544489753929 0.12009437730219757 0.1317924727418063 2.112741252324198 0.032517757589076914 0.061381118229923336 2.0668719973345607e-06 5.684686418666675 0.44429677454451 VHS(ph)PCPTSGSEK ddPTM_PC-9_Lapatinib_30min_R1 3 VHSPCPTSGSEK 12 0 X6RLP6;Q96LT9-2;Q96LT9 X6RLP6 RNPC3 RNA-binding protein 40 1 VHS(0.996)PCPT(0.003)S(0.001)GSEK;VHS(0.924)PCPT(0.058)S(0.018)GSEK;VHS(1)PCPTSGSEK 103.14 0.0021899999999999997 22424400.0 79221.3 133667.0 120854.0 107219.0 137494.0 142359.0 142519.0 144767.0 136339.0 115750.0 True False 78091.58973459306 133357.5022739759 110917.85062993069 115104.24293209895 129406.87324360467 136270.63742503745 149897.9364691773 151493.40331791653 120983.06610668193 135757.23327281984 0.5752296791262606 0.9823233654591251 0.81703087162235 0.8478682141435785 0.9532226764193596 1.0037817811975136 1.1041616925702964 1.1159140449884761 0.8911721548092578 1.0 17.050669542660316 -3.8418091775557768 0.44401289374233227 1.036258892274826 1.5860236657127625e-16 0.5653991189871245 0.09897111920733655 8.91168209812379 0.7204665071507839 0.06833669758811167 5.785705144114534 0.00014394309035544668 3.8418091775557768 -1.0362588922748257 VHS(ph)PPASLVPR ddPTM_PC-9_AZD4547_30min_R2 2 VHSPPASLVPR 11 0 Q9BTE3;Q9BTE3-2;Q9BTE3-3 Q9BTE3 MCMBP Mini-chromosome maintenance complex-binding protein 1 VHS(1)PPASLVPR;VHS(1)PPASLVPR 124.48 0.00028853 13000200.0 50799.0 47512.0 106841.0 145130.0 112620.0 107479.0 66369.0 122689.0 78625.0 81895.0 True False 66952.02531516031 62869.32485220047 105424.21853133063 111672.52073614828 96984.6569627034 100758.32113939946 72275.71242621042 103730.23416274693 82780.95698388123 79027.88097689803 0.8471949960891927 0.7955334759713331 1.3340129740053255 1.4130775032269074 1.2272207702374638 1.2749718187288082 0.9145596659404109 1.3125776989145141 1.047490530691065 1.0 16.270074104368526 -5.251552073919918 24.51363295216113 1.2040764410189995 0.8213641593458528 0.4857629156346588 0.15140015861430156 425.4187615976426 1054735.0886774396 0.03894645718184753 0.10027336576478706 5.603352265470311e-06 5.251552073919918 -0.38271228167314664 VHS(ph)PPASLVPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VHSPPASLVPR 11 0 Q9BTE3;Q9BTE3-2;Q9BTE3-3 Q9BTE3 MCMBP Mini-chromosome maintenance complex-binding protein 1 VHS(1)PPASLVPR;VHS(1)PPASLVPR 120.59 0.00048261 11824300.0 16915.6 24539.0 16851.6 23479.0 24454.0 21931.0 21879.0 17841.5 17010.4 15387.3 True False 19779.07698167096 26975.069747398764 17253.406054048886 22163.547749945028 19662.41424450782 20780.899752680984 19806.462729757277 17373.17952963184 17259.14491948488 18176.895684200215 1.0881438351909232 1.4840306186521237 0.9491943153442836 1.2193252431552493 1.081725647003567 1.1432590093337132 1.0896504592351002 0.9557836404778962 0.9495100384212983 1.0 14.149818211456495 -6.747464826865066 0.480703877803993 0.9537668965064698 1.248345402252052 0.2986398744349562 0.12979577444292176 1.3289817836821187 0.6494068615858379 0.1159687136352085 0.16319205874613804 1.7886903877310875e-07 6.747464826865066 0.2945785057455821 VHS(ph)PPASLVPR ddPTM_PC-9_Lapatinib_30min_R1 2 VHSPPASLVPR 11 0 Q9BTE3;Q9BTE3-2;Q9BTE3-3 Q9BTE3 MCMBP Mini-chromosome maintenance complex-binding protein 1 VHS(1)PPASLVPR;VHS(1)PPASLVPR 92.906 0.0075615 6558900.0 27606.0 22696.6 37615.0 22903.0 28669.7 37610.0 26510.8 25100.5 44555.0 24664.9 True False 27212.33337767961 22644.04741717495 34522.439898098964 24587.363022168294 26983.404612798884 36001.50797319213 27883.39950565935 26266.760863880332 39536.74671505011 28928.19510108663 0.940685489799446 0.782767377572214 1.1933838173264464 0.8499445933716314 0.9327717999172823 1.2445127615943037 0.9638831392080858 0.9079986073135159 1.3667201350410207 1.0 14.820188692449099 -5.469009212117255 0.44092855530514447 1.0932113410623656 0.8169702051568635 0.13895874441997114 0.164910459289937 6.196121220739308 1.4613699665075388 0.1331847861621504 0.8457628159175191 3.3961806864289737e-06 5.469009212117255 -0.27624113590550214 VHSEAIS(ph)PAPEEK ddPTM_PC-9_AZD4547_30min_R2 1 VHSEAISPAPEEK 13 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 VHSEAIS(1)PAPEEK 110.25 0.00069697 10208000.0 30944.0 23506.0 29784.0 44585.0 40994.0 43926.0 29552.0 45982.0 36283.0 41911.0 True False 40783.548324815834 31103.854815116683 29389.04469948011 34306.61708138337 35302.69070794769 41179.300276047106 32182.07075019024 38876.53846124292 38200.84530678742 40443.70864671556 1.0084027822737238 0.7690653467716203 0.7266654241874725 0.848255964383954 0.8728846065113424 1.0181880360121545 0.7957250169935578 0.9612505816624729 0.9445435788413958 1.0 15.303627676515951 -6.465703414499806 3.739371864534171 0.9334315981254027 0.8263551062582368 0.2319919227673285 0.08877986093386446 0.35596310283945704 9.961183170146178 0.029170232758680522 0.03221724390359349 3.4221306460369837e-07 6.465703414499806 -0.10707649186716584 VHSEAIS(ph)PAPEEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VHSEAISPAPEEK 13 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 VHS(0.002)EAIS(0.998)PAPEEK;VHS(0.002)EAIS(0.998)PAPEEK;VHSEAIS(1)PAPEEK;VHSEAIS(1)PAPEEK 167.37 0.00028407 27418900.0 124764.0 134009.0 135757.0 173031.0 213106.0 207042.0 216116.0 229491.0 204827.0 192694.0 True False 145884.0809986758 147312.52788537258 138993.96174128933 163336.63404407122 171349.40909422073 196184.35304338936 195643.92793565601 223467.10441581428 207822.2073803869 227627.89683513498 0.6408884105463396 0.6471637700543675 0.6106191889211149 0.7175598259925572 0.7527610256765879 0.861864278373053 0.8594901181086599 0.981721078667549 0.9129909394669107 1.0 17.796317851762332 -6.7491948218006685 0.7336778352746456 0.975487579595641 0.6174038265691992 0.9454834847395495 0.03190350138367201 0.13638153518419213 0.16140239529341355 0.021660055376660804 0.021857700394075523 1.7815793827429917e-07 6.7491948218006685 -0.3580837530264418 VHSEAIS(ph)PAPEEK ddPTM_PC-9_Lapatinib_30min_R1 2 VHSEAISPAPEEK 13 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 VHS(0.01)EAIS(0.99)PAPEEK;VHSEAIS(1)PAPEEK 104.09 0.0013777999999999998 36352200.0 133417.0 104782.0 135830.0 109461.0 168603.0 163550.0 151082.0 140677.0 164081.0 143397.0 True False 131514.44911431868 104539.38371678701 124662.58171896257 117511.12709119139 158686.10302625175 156555.34775367117 158904.28671009667 147213.3669866376 145600.469930471 168182.98038550824 0.7819724018022625 0.621581229427391 0.7412318501742066 0.6987099813657299 0.943532470779815 0.930863202654726 0.9448297702053858 0.8753166738346282 0.8657265413939407 1.0 17.35967219099429 -6.259173436278549 24.981631852242476 0.9215907851065915 0.7066642378431516 0.8069909878699167 0.05165869654478259 83.18544634583445 917104.2943096532 0.015139390621201433 0.018607343962511708 5.505877742822038e-07 6.259173436278549 -0.21492654726343996 VHSFPTLK ddPTM_PC-9_Lapatinib_30min_R1 1 VHSFPTLK 8 0 P07237;H7BZ94;H0Y3Z3;I3L0S0 P07237 P4HB Protein disulfide-isomerase 0 104.44 0.0032381 6523900.0 128490.0 118170.0 127250.0 128210.0 126360.0 130480.0 119740.0 117630.0 122650.0 109670.0 False True 126657.70903781992 117896.3846253432 116787.99619920459 137638.99109602187 118927.75323331832 124899.67456373593 125939.55130768039 123095.51922942746 108835.86543824249 128626.31337391051 0.984695166296433 0.9165806088418633 0.907963488463729 1.070068693455529 0.9245989418012864 0.9710273993522506 0.9791118784659572 0.9570010676710814 0.8461399738781431 1.0 16.972826282660847 -9.859906122822439 6.221592169836919 0.9999999976149018 0.9528798158394165 0.06397162858308392 0.055953731614122974 18142998.955256235 0.33320536028765096 0.0532012618709027 0.013300315566820752 1.3806826809789843e-10 9.859906122822439 -0.04712018177548527 VHVGDEDFVHLR ddPTM_PC-9_AZD4547_30min_R2 4 VHVGDEDFVHLR 12 0 P04080 P04080 CSTB Cystatin-B 0 ;;; 199.03 3.1694e-06 129629400.0 89840.1 84476.5 136245.0 187495.0 134605.8 120225.5 131974.0 171071.0 127074.0 130451.0 False True 118407.3830098337 111781.87659700526 134438.3022790984 144270.92451887342 115918.10813523628 112707.78047939477 143719.43033248547 144635.90777050384 133790.8722132874 125883.95019619403 0.9406074628679203 0.8879756031073839 1.0679542711328343 1.146062895976991 0.9208331002846218 0.8953308209961335 1.141681922981399 1.1489622588509838 1.06281120035374 1.0 16.94173483018327 -7.275596702951419 24.738890735318606 1.100777369550759 0.9817781030462781 0.289900282380942 0.08466975050111279 957.1055420641661 1672464.8581780063 0.03805136471627359 0.025795403639802452 5.301555314634389e-08 7.275596702951419 -0.1189992665044809 VHVGDEDFVHLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 VHVGDEDFVHLR 12 0 P04080 P04080 CSTB Cystatin-B 0 ;;;; 211.64 5.8995e-09 97265800.0 121590.8 166479.0 182134.0 153962.0 204440.0 150288.0 163248.0 128670.0 127723.1 121834.59999999999 False True 142173.7209122327 183005.9348986184 186476.7653070411 145336.00829153875 164381.4495848192 142406.6327130966 147783.96762682978 125292.54883713424 129590.80870913397 143922.24853783735 0.9878508872438513 1.2715611155179103 1.295677125680927 1.0098230799481271 1.1421545400717048 0.9894692041005578 1.0268319813526063 0.8705571939712619 0.9004223462716703 1.0 17.134930105946005 -6.816501671760154 1.0153908852309408 0.922412609390987 1.1740202780829452 0.466079976067976 0.0993014621042486 0.4389800349626722 0.9644270802080966 0.058075198975406514 0.04994520755107465 1.525802521417719e-07 6.816501671760154 0.25160766869195816 VHVGDEDFVHLR ddPTM_PC-9_Lapatinib_30min_R1 4 VHVGDEDFVHLR 12 0 P04080 P04080 CSTB Cystatin-B 0 ;;; 196.11 5.4665999999999995e-06 52466700.0 94088.0 100602.7 114047.0 93038.0 103529.0 108469.0 85368.0 82826.0 108771.0 78182.8 False True 92746.28786637401 100369.76062916164 104670.4958941512 99880.32488566988 97439.6277658454 103830.0337235887 89787.93733116792 86674.39833117867 96520.06457059176 91696.59280796727 1.0114474815940548 1.0945854971880784 1.1414872972799994 1.0892479407041997 1.0626308435462297 1.1323216113496333 0.9791850992675759 0.9452303043875777 1.0526025189695531 1.0 16.48458050780411 -7.272826342313242 24.90119818298148 0.9896903313856363 1.0901415271065076 0.5481494779753403 0.04187717114195892 528.2460095227694 1155172.5961026016 0.01738496113383364 0.011839586245857469 5.3354819827565505e-08 7.272826342313242 0.10045119572087124 VHVQFFDDS(ph)PTR ddPTM_PC-9_AZD4547_30min_R2 3 VHVQFFDDSPTR 12 0 P52701-2;P52701;A0A087WWJ1;F8WAX8;A0A494C0M1;C9J7Y7;C9JH55;C9J8Y8 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 VHVQFFDDS(0.931)PT(0.069)R;VHVQFFDDS(0.792)PT(0.208)R;VHVQFFDDS(0.784)PT(0.216)R 166.64 5.1316e-05 68969000.0 178655.0 168267.0 230292.0 284504.0 231419.0 223216.0 178158.0 254491.0 188120.0 219422.0 True False 235463.5737451517 222656.01710947175 227238.17760988028 218915.99834298278 199290.46643271056 209258.2682333497 194013.71686222256 215165.26357140165 198063.63914540823 211740.1025668594 1.1120405199142724 1.0515533638185781 1.0731938582023082 1.0338901119302968 0.941203220442298 0.9882788649697285 0.9162823409937684 1.016176250804737 0.9354091962001735 1.0 17.691935009229574 -6.039367996611371 3.146930303168614 0.9657323029061425 1.0757412861918094 0.7165688231919851 0.032071648322317826 0.1294358549678494 2.584277871134856 0.009125757341474881 0.01304375265339707 9.133390016160927e-07 6.039367996611371 0.11000898328566688 VHVQFFDDS(ph)PTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 VHVQFFDDSPTR 12 0 P52701-2;P52701;A0A087WWJ1;F8WAX8;A0A494C0M1;C9J7Y7;C9JH55;C9J8Y8 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 VHVQFFDDS(0.989)PT(0.011)R;VHVQFFDDS(0.654)PT(0.346)R;VHVQFFDDS(0.765)PT(0.235)R;VHVQFFDDS(0.769)PT(0.231)R;VHVQFFDDS(0.751)PT(0.249)R;VHVQFFDDS(0.783)PT(0.217)R;VHVQFFDDS(0.762)PT(0.238)R 142.95 4.7026999999999995e-05 72204800.0 159650.3 176752.7 195401.0 193543.4 212305.0 182851.5 187171.5 164100.9 172104.0 155551.1 True False 186675.94255284301 194299.53993810053 200060.1009024187 182699.79077416915 170705.3592941945 173262.4454483312 169441.26051568903 159793.4252542759 174620.6954112204 183751.28308816982 1.0159164029525163 1.0574050786076379 1.0887548513412195 0.9942776328070801 0.9290022710333105 0.9429182889851945 0.9221228699360191 0.8696180106541179 0.9503100739026227 1.0 17.48739479839113 -6.053396939642518 3.2130415493325004 0.928952234572677 1.0540776320432828 0.6948765652568181 0.03494264095376813 0.13026446325105778 2.6777153049220406 0.010549075164151428 0.014891460263482892 8.843069949893019e-07 6.053396939642518 0.1251253974706058 VHVQFFDDS(ph)PTR ddPTM_PC-9_Lapatinib_30min_R1 4 VHVQFFDDSPTR 12 0 P52701-2;P52701;A0A087WWJ1;F8WAX8;A0A494C0M1;C9J7Y7;C9JH55;C9J8Y8 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 VHVQFFDDS(0.961)PT(0.039)R;VHVQFFDDS(0.77)PT(0.23)R;VHVQFFDDS(0.759)PT(0.241)R;VHVQFFDDS(0.89)PT(0.11)R 144.88 4.0654e-05 82211000.0 205667.0 208740.0 235937.0 193845.0 193176.0 209760.0 183447.0 185248.0 232771.0 155468.0 True False 202734.1508652916 208256.67535494704 216539.17060315795 208101.00794796328 181813.76747862864 200789.0537744424 192944.98804693544 193855.29836107217 206553.87879270388 182340.43665191188 1.1118441668115084 1.1421310553978177 1.1875543054475157 1.141277336881826 0.997111616145306 1.1011767738482987 1.0581579795998166 1.0631503462456997 1.132792498391432 1.0 17.4762750099668 -6.113770640058786 8.777381579935117 1.0640745107521148 1.1495687979845304 0.5047536764485465 0.04201043136230556 0.2726669897517721 19.267576284205827 0.01203730895018046 0.015568503312037336 7.695367413344323e-07 6.113770640058786 0.08549428723241559 VHVQFFDDSPT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 VHVQFFDDSPTR 12 0 P52701-2;P52701;A0A087WWJ1;F8WAX8;A0A494C0M1;C9J7Y7;C9JH55;C9J8Y8 P52701-2 MSH6 DNA mismatch repair protein Msh6 1 VHVQFFDDS(0.087)PT(0.913)R 204.17 2.3363000000000003e-07 25911000.0 14827.0 14233.0 23446.0 30944.0 25549.0 21462.0 19994.0 33307.0 18718.0 18586.0 True False 19541.67757924134 18833.538908515096 23135.090720655735 23810.338880034247 22001.96235784153 20119.97774722313 21773.4272664897 28160.168468718603 19707.395266445634 17935.30979713812 1.089564540577913 1.0500816055890099 1.2899186566795364 1.327567750395568 1.2267400232669698 1.1218082082102427 1.2139978351510836 1.5700965741451551 1.0988042854765898 1.0 14.130515044774343 -5.25755624715613 24.801888483245612 1.250250372431553 1.0698230544720053 0.15279580625963807 0.146478032106806 467.44593870408244 2985579.998656633 0.0368151656225904 0.09009237833250734 5.526418285310767e-06 5.25755624715613 -0.1804273179595477 VHYCER ddPTM_PC-9_AZD4547_30min_R2 1 VHYCER 6 0 H0YH15;O60306 H0YH15 AQR Intron-binding protein aquarius 0 67.377 0.044860000000000004 0.0 537.93 0.0 530.66 0.0 706.31 791.11 0.0 0.0 807.41 575.32 False True 708.9805503609159 0.0 523.6231016729154 0.0 608.2510482980571 741.6417666389757 0.0 0.0 850.0880442398156 555.1782219137792 1.27703235173195 0.0 0.9431621792870606 0.0 1.0955960163590859 1.3358624985008054 0.0 0.0 1.5311984704829376 1.0 9.116807165916358 -6.327007542655485 24.999954082186886 0.7611910893824185 0.5430982978147606 0.040915388523507734 0.594933809259719 925.8544205084906 353008.338314458 0.18588121286128056 0.21076950428586505 4.7096914671930563e-07 6.327007542655485 -0.21809279156765793 VIAHTQMR ddPTM_PC-9_AZD4547_30min_R2 1 VIAHTQMR 8 0 P39023;G5E9G0;B5MCW2;H7C422;H7C3M2 P39023 RPL3 60S ribosomal protein L3 0 143.89 0.0014177999999999999 3484800.0 17468.0 15298.0 19765.0 25153.0 14244.0 14518.0 14746.0 18900.0 14277.0 25487.0 False True 23022.460643028797 20242.77933130501 19502.90318577842 19354.364459976136 12266.466469337143 13610.18716495133 16058.365433212804 15979.43927879369 15031.65307292682 24594.70788763904 0.9360737581518326 0.8230542693893409 0.7929715317163946 0.7869320728831819 0.49874414143792695 0.5533786872822191 0.65291954295922 0.6497104723420901 0.6111742876393959 1.0 14.586060299763885 -6.063000725966087 6.5262681604924095 0.637344446823791 0.8391699994870283 0.2957766405198796 0.13065672040742027 0.25949023880087996 21.857981380217282 0.03687946470174387 0.048281214191718255 8.649664728976619e-07 6.063000725966087 0.20182555266323732 VIAHTQMR ddPTM_PC-9_Lapatinib_30min_R1 2 VIAHTQMR 8 0 P39023;G5E9G0;B5MCW2;H7C422;H7C3M2 P39023 RPL3 60S ribosomal protein L3 0 ; 138.83 0.0024142 11722400.0 45614.0 42752.0 53871.0 53513.0 58076.0 54350.0 48053.0 41811.0 62798.0 43660.0 False True 44963.53599541689 42653.010370675045 49441.93432807363 57448.52453413488 54660.08386180913 52025.57719603806 50540.94921486526 43753.69169855982 55725.02794774363 51206.57282670684 0.8780813382606639 0.8329596771692036 0.9655388282944634 1.1218974706343272 1.0674427294087743 1.0159941258342535 0.9870012075579793 0.8544545999325313 1.0882397487589754 1.0 15.644041384616147 -5.404833132144534 4.509378024382032 1.015602216671174 0.8575034259486135 0.46519671804820284 0.06907116844114249 0.20623430968132556 6.6085425228769195 0.019547557845703903 0.04249784469392168 3.937013172461643e-06 5.404833132144534 -0.1580987907225605 VIAIDSDAES(ph)PAKR ddPTM_PC-9_AZD4547_30min_R2 1 VIAIDSDAESPAKR 14 1 P28749 P28749 RBL1 Retinoblastoma-like protein 1 1 VIAIDS(0.002)DAES(0.998)PAKR 71.286 0.011664 30038000.0 71380.0 50825.0 69879.0 93955.0 76246.0 77789.0 61754.0 62334.0 59138.0 75736.0 True False 94077.35520376649 67253.18731295447 68952.35880187248 72295.12634027979 65660.55900176073 72924.84153288341 67249.9863666502 52701.71259282146 62263.91394738015 73084.50569224429 1.2872407675564255 0.9202112906962079 0.9434606986633788 0.9891990874880028 0.8984196907379318 0.9978153487138133 0.920167492817657 0.7211065066889295 0.8519441071349763 1.0 16.157277959046844 -4.761111035522846 6.746979960594243 0.9118285387173429 1.296522895510181 0.6655188062281676 0.07897187258784037 0.07471398761049892 17.689589384244822 0.021245708680640907 0.13171100909027908 1.7333607749326747e-05 4.761111035522846 0.38469435679283814 VIAIDSDAES(ph)PAKR ddPTM_PC-9_Lapatinib_30min_R1 2 VIAIDSDAESPAKR 14 1 P28749 P28749 RBL1 Retinoblastoma-like protein 1 1 VIAIDS(0.179)DAES(0.821)PAKR;VIAIDS(0.003)DAES(0.997)PAKR 84.352 0.010754000000000001 38055200.0 134985.0 127194.0 125180.0 132623.0 132250.0 120312.0 116209.0 103624.0 99950.0 94809.0 True False 133060.08914678267 126899.49010777623 114888.18360877353 142376.5378373584 124471.31501350395 115166.53622097019 122225.73340499603 108438.74933801079 88692.57847983972 111196.60932494869 1.1966200224499883 1.1412172626319854 1.0331986227479022 1.2804035905563715 1.1193804898291704 1.0357018700491147 1.0991857948457497 0.9751983445926968 0.7976194509731347 1.0 16.762753271628974 -7.672881469842097 1.4294628837526546 0.8956577475285287 1.1429146086923467 0.5759786833181904 0.08216804389292137 0.30487844264936614 1.1717660436261725 0.06304988953654539 0.026196702429863463 2.1238240292256177e-08 7.672881469842097 0.24725686116381806 VIAINVDDPDAANYNDINDVKR ddPTM_PC-9_AZD4547_30min_R2 1 VIAINVDDPDAANYNDINDVKR 22 1 Q15181 Q15181 PPA1 Inorganic pyrophosphatase 0 156.08 4.0948e-06 5806400.0 31606.0 27476.0 39734.0 51837.0 47257.0 41367.0 35188.0 41200.0 36299.0 34890.0 False True 41656.05055436043 36357.07967753539 39207.10119826562 39886.78052366648 40696.18126519699 38780.31495058149 38319.66383181153 34833.48668181484 38217.691034122756 33668.51171968951 1.2372406271228131 1.0798540779060808 1.1645035433905775 1.1846909318638073 1.208731220554595 1.151827418849125 1.1381454621708749 1.0346013204214206 1.1351167331751366 1.0 15.039112329343503 -8.164428188677995 0.6890864167424897 1.0108400249734204 1.172561388836584 0.5216743871122079 0.049315662663746596 0.544380787076243 0.5701010954258359 0.047237461927777454 0.020640550117280783 6.848127086614153e-09 8.164428188677995 0.1617213638631636 VIAINVDDPDAANYNDINDVKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VIAINVDDPDAANYNDINDVKR 22 1 Q15181 Q15181 PPA1 Inorganic pyrophosphatase 0 ; 193.71 2.461e-19 9826000.0 32460.0 31835.0 34673.0 42527.0 44367.0 36928.0 42634.0 36264.0 40500.0 32601.0 False True 37954.83688577643 34995.368409814546 35499.735818084744 40144.35006439423 35673.604841174405 34991.430671971335 38595.39887656983 35312.10842488409 41092.23588152759 38511.30323062598 0.985550570918955 0.9087038213234135 0.9218004284480745 1.0424043513663692 0.9263151814817084 0.9086015724376869 1.0021836613900144 0.9169284200385684 1.0670175360061338 1.0 15.232994324614971 -8.261925083965606 24.999988718304525 1.0335087699719567 0.9515824343652769 0.3425635574563023 0.04541018608654139 48.09853284878279 2475331.9440062735 0.035237858228407234 0.011196689202326119 5.471103315842509e-09 8.261925083965606 -0.08192633560667983 VIAINVDDPDAANYNDINDVKR ddPTM_PC-9_Lapatinib_30min_R1 1 VIAINVDDPDAANYNDINDVKR 22 1 Q15181 Q15181 PPA1 Inorganic pyrophosphatase 0 177.41 1.5165e-41 0.0 23489.0 16717.0 19770.0 18038.0 18866.0 17397.0 16738.0 15300.0 18693.0 18420.0 False True 23154.042552644965 16678.292813589418 18144.586914406926 19364.574693004037 17756.33897198311 16652.97086438774 17604.611740337015 16010.893855396067 16587.597493983416 21603.872456892812 1.0717542699275455 0.7720047804794429 0.8398765985409165 0.8963473901099468 0.821905378649737 0.7708326781513901 0.814882228890413 0.7411122189942257 0.7678066757282244 1.0 14.399002315716691 -4.755156122650272 24.990119724960998 0.8174768810613586 1.071754693019543 0.5079459806368062 0.07252960733466411 165.12122818963834 656666.6379318656 0.01740533809906777 0.15896760013696806 1.7572917791548822e-05 4.755156122650272 0.25427781195818433 VIDPATATSVDLR ddPTM_PC-9_Lapatinib_30min_R1 1 VIDPATATSVDLR 13 0 P50991;P50991-2 P50991 CCT4 T-complex protein 1 subunit delta 0 213.35 1.2295e-13 5350400.0 16521.0 22233.0 17174.0 17143.0 18266.0 17523.0 15854.0 19859.0 17402.0 16177.0 False True 16285.407510419662 22181.520854491457 15762.02001355713 18403.75340737157 17191.629792337724 16773.582138108097 16674.84254578222 20781.72163884382 15442.00350881612 18973.172895502445 0.8583386447861912 1.1690991789649239 0.8307529847732262 0.9699881779780831 0.9061019939586893 0.8840683754104325 0.8788642067207937 1.0953213652403964 0.813886195728318 1.0 14.211673341263229 -5.291073444187411 24.99934946474873 0.9239747995716141 1.013719169471884 0.1078220687826783 0.10502358005245477 1305.4210393800481 1101253.4551558893 0.025528754322341137 0.053152575905236116 5.11595311578435e-06 5.291073444187411 0.0897443699002698 VIEEEWQQVDR ddPTM_PC-9_Lapatinib_30min_R1 1 VIEEEWQQVDR 11 0 P42166 P42166 TMPO Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin 0 107.55 0.010574 3621700.0 3954.6 2590.4 4438.1 3545.4 3372.8 4311.5 3038.7 3964.2 4223.5 2890.7 False True 3898.2066788151787 2584.402087953701 4073.216549561425 3806.1405431076932 3174.4185351799324 4127.10719559739 3196.0290175267105 4148.391204023599 3747.8049545733174 3390.3536433843665 1.1497935285959893 0.7622809770882376 1.2014134742284293 1.1226382093014562 0.9363089721847186 1.2173087617719935 0.9426830807939922 1.2235865754353972 1.1054318660492688 1.0 11.727220051518342 -5.287281497891338 24.99937568247813 1.0960942206130289 0.9560370756915315 0.14656395864959415 0.1327458544438271 1152.2665384502593 1114687.7155370791 0.03234899609509789 0.06737413761611308 5.160817506601535e-06 5.287281497891338 -0.14005714492149735 VIEPPAAS(ph)CPSSPR ddPTM_PC-9_AZD4547_30min_R2 1 VIEPPAASCPSSPR 14 0 A0A0A0MRX4;Q3MIN7;Q3MIN7-2 A0A0A0MRX4 RGL3 Ral guanine nucleotide dissociation stimulator-like 3 1 VIEPPAAS(0.69)CPS(0.078)S(0.231)PR 71.529 0.024884 11429000.0 17159.0 15656.0 24261.0 35722.0 25273.0 26177.0 19304.0 30138.0 23059.0 25214.0 True False 22615.205070628075 20716.495830233427 23939.283288144205 27486.844799398372 21764.280193734758 24540.14805186189 21022.018603196797 25480.86460234307 24277.8516641185 24331.265534544313 0.9294709738184452 0.8514351956260221 0.9838897715433835 1.1296923606531657 0.894498486436512 1.0085849425719766 0.8639919930737178 1.0472478123329267 0.9978047228842257 1.0 14.570523740225646 -5.301518997295819 10.741920959319875 0.9900750143732809 0.8904877460940072 0.23838247800563372 0.07167773506548686 1.0412839857675753 277.5533994562489 0.018593666161100135 0.03889633027710651 4.994373328980248e-06 5.301518997295819 -0.09958726827927378 VIEPPAAS(ph)CPSSPR ddPTM_PC-9_Lapatinib_30min_R1 1 VIEPPAASCPSSPR 14 0 A0A0A0MRX4;Q3MIN7;Q3MIN7-2 A0A0A0MRX4 RGL3 Ral guanine nucleotide dissociation stimulator-like 3 1 VIEPPAAS(0.925)CPS(0.064)S(0.011)PR 147.52 0.00020549 11884000.0 48730.0 52753.0 57505.0 45087.0 61523.0 68305.0 70556.0 65801.0 75751.0 68804.0 True False 48035.10126401245 52630.853669634664 52777.160875719266 48402.848385822865 57904.33809887186 65383.75437673193 74209.04444684066 68858.35467836056 67219.12468660671 80696.67972443272 0.595254989772135 0.6522059377084817 0.6540189888350487 0.5998121428429456 0.7175553975282087 0.8102409491940415 0.9196046813853263 0.8532984865486622 0.8329850114794082 1.0 16.300221694395262 -6.742470796242315 1.8890236514675978 0.8898009106493907 0.6286865714952539 0.8738149561164636 0.04725445607905207 0.1130547896980209 0.8323354374738119 0.01862096414404474 0.017291361796374024 1.809377576196924e-07 6.742470796242315 -0.26111433915413684 VIET(ph)PENDFK ddPTM_PC-9_AZD4547_30min_R2 3 VIETPENDFK 10 0 A0A024QZ33;Q9H0G5 A0A024QZ33 CCDC55;NSRP1 Nuclear speckle splicing regulatory protein 1 1 VIET(1)PENDFK;VIET(1)PENDFK;VIET(1)PENDFK 124.12 0.0010351 17862400.0 103143.0 123014.0 122937.0 118842.0 131117.0 136324.0 140623.0 150093.0 134033.0 136792.0 True False 135940.32849232442 162775.8698301187 121306.7750543911 91444.81299059698 112913.66779416463 127799.63872949587 153138.17457715218 126899.57564402049 141117.71074620727 132002.95371624443 1.0298279293397012 1.2331229358702396 0.9189701566462974 0.6927482334006567 0.8553874335030834 0.9681574171758 1.160111726790147 0.961338910012618 1.0690496445220163 1.0 17.010210686324342 -7.020444023852919 24.264462229715825 1.0472220775641319 0.9429278075678729 0.11194762635924105 0.13616839125654742 1385.1682741644743 1644015.1845296614 0.05816299550229936 0.045653314885495094 9.54016697978848e-08 7.020444023852919 -0.10429426999625901 VIET(ph)PENDFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VIETPENDFK 10 0 A0A024QZ33;Q9H0G5 A0A024QZ33 CCDC55;NSRP1 Nuclear speckle splicing regulatory protein 1 1 VIET(1)PENDFK 79.82 0.031010000000000003 0.0 34520.0 35031.0 29504.0 33754.0 44678.0 31999.0 45657.0 35846.0 25654.0 26279.0 True False 40363.554198921825 38508.646168186395 30207.487254543106 31862.8728119445 35923.66662370658 30320.91610897993 41332.03843194513 34905.08048197646 26029.141217400233 31043.17467555046 1.3002392513260597 1.240486727619251 0.9730798338204262 1.0264051001536139 1.1572162640955657 0.9767337402144188 1.3314372277941715 1.124404344812956 0.8384819365108533 1.0 14.921988483932427 -5.110999879078663 5.394773980686504 1.0683189307586531 1.2863734239536493 0.32219958417247285 0.12547397851555822 0.2610307036053142 10.480516520167605 0.032431441446976995 0.09167577373413364 7.744620134372392e-06 5.110999879078663 0.21805449319499615 VIET(ph)PENDFK ddPTM_PC-9_Lapatinib_30min_R1 2 VIETPENDFK 10 0 A0A024QZ33;Q9H0G5 A0A024QZ33 CCDC55;NSRP1 Nuclear speckle splicing regulatory protein 1 1 VIET(1)PENDFK;VIET(1)PENDFK 129.74 0.00057757 11685400.0 40581.0 88199.0 82398.0 72275.0 81268.0 78538.0 75224.0 71679.0 77174.0 65524.0 True False 40002.30749835601 87994.78063443043 75623.55450547792 77590.34460233219 76487.97601903544 75179.11282102001 79118.73064614114 75009.46801705437 68481.85144175231 76849.7360947582 0.5205262832527086 1.1450238492156957 0.9840444268049487 1.0096370989050736 0.9952926308650338 0.9782611709729456 1.029525079287002 0.9760536838352349 0.8911136839469687 1.0 16.229752685198257 -4.750590191491949 24.99999544350793 0.9999896519891718 0.5205252659067244 0.8552029283968848 0.0593091562672683 164.4174489966176 378845.7121710249 0.014469211672316724 0.21000177443708198 1.7758644298583593e-05 4.750590191491949 -0.47946438608244735 VIGQDHDFSES(ph)SEEEAPAEASSGALR ddPTM_PC-9_AZD4547_30min_R2 2 VIGQDHDFSESSEEEAPAEASSGALR 26 0 P23497;P23497-5;P23497-2;P23497-3;P23497-4;E9PHV6;P23497-7;P23497-6;H7C4B4;H7C1G8 P23497 SP100 Nuclear autoantigen Sp-100 1 VIGQDHDFS(0.005)ES(0.745)S(0.25)EEEAPAEASSGALR;VIGQDHDFS(0.031)ES(0.899)S(0.07)EEEAPAEASSGALR 121.3 9.949e-07 0.0 10351.5 8881.6 11035.8 15412.6 13404.7 10873.099999999999 10556.0 12528.7 10005.3 12069.8 True False 13643.061675424346 11752.403510845756 10889.458081336372 11859.463192296269 11543.688786964596 10193.203338147976 11495.46355031836 10592.67729588479 10534.159731775211 11647.239975761195 1.1713557635814673 1.009029051973121 0.9349389300811329 1.0182209018597306 0.9911093796459851 0.8751604121972947 0.9869688934237902 0.9094581478469551 0.9044339906877175 1.0 13.50770050223731 VIGQDHDFSES(ph)SEEEAPAEASSGALR ddPTM_PC-9_Lapatinib_30min_R1 2 VIGQDHDFSESSEEEAPAEASSGALR 26 0 P23497;P23497-5;P23497-2;P23497-3;P23497-4;E9PHV6;P23497-7;P23497-6;H7C4B4;H7C1G8 P23497 SP100 Nuclear autoantigen Sp-100 1 VIGQDHDFS(0.092)ES(0.655)S(0.228)EEEAPAEAS(0.012)S(0.014)GALR;VIGQDHDFSES(0.77)S(0.23)EEEAPAEASSGALR 101.14 1.2500999999999999e-09 4182700.0 13809.1 12589.599999999999 17191.8 9866.2 14148.3 15302.7 11826.4 12714.6 15380.6 10220.0 True False 13612.179701721212 12560.44955470272 15778.356566267108 10591.793260678367 13316.124810628033 14648.239193335994 12438.71312498038 13305.366732929331 13648.274863101777 11986.513382705993 1.1356246196963924 1.0478818279905144 1.3163424644427415 0.8836425507988076 1.1109256199421917 1.2220600541330318 1.0377257112086335 1.110028104763656 1.138635934181941 1.0 13.549124450562976 -10.795697705832493 4.416945592485426 0.9999332547090215 1.109917852786365 0.08708300247459566 0.10813615186570683 6.875742831157232e-05 1.131991087602422e-05 0.10019260927028943 0.024285380475857054 1.6006718014273047e-11 10.795697705832493 0.1099845980773434 VIGSGCNLDSAR ddPTM_PC-9_AZD4547_30min_R2 3 VIGSGCNLDSAR 12 0 P00338-3;P00338;P00338-4;P00338-2;P00338-5;F5H155;F5H245;G3XAP5;A0A087WUM2;F5H5G7;Q6ZMR3;P07864;A0A5F9ZHM4;P07195;A0A3B3IS95;A8MW50 P00338-3;A0A5F9ZHM4 LDHA;LDHC;LDHAL6A;LDHB L-lactate dehydrogenase A chain;L-lactate dehydrogenase;L-lactate dehydrogenase A-like 6A;L-lactate dehydrogenase C chain;L-lactate dehydrogenase B chain 0 ;; 189.17 0.00025712 39308000.0 44593.0 42525.0 64469.0 70283.0 65000.0 55551.0 45386.0 51012.0 43782.4 54920.0 False True 58772.646407979344 56270.37462830074 63614.09893670371 54080.34021152556 55975.871981670505 52077.38718833253 49425.26607566777 43129.26753914414 46096.6482804589 52997.26751634702 1.1089750313985698 1.0617599220741736 1.2003279021334812 1.0204363874957225 1.0562029818689187 0.9826428725267627 0.9326002715219711 0.8138017214914128 0.8697929240642526 1.0 15.693630357296229 -6.872396869008755 1.2390683211846316 0.8818477570710421 1.1063192487969682 0.6800977157093553 0.06082454704073901 0.24419108156062735 0.7822906883938034 0.0314244175049171 0.02554699859259964 1.3415384698835158e-07 6.872396869008755 0.22447149172592606 VIGSGCNLDSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VIGSGCNLDSAR 12 0 P00338-3;P00338;P00338-4;P00338-2;P00338-5;F5H155;F5H245;G3XAP5;A0A087WUM2;F5H5G7;Q6ZMR3;P07864;A0A5F9ZHM4;P07195;A0A3B3IS95;A8MW50 P00338-3;A0A5F9ZHM4 LDHA;LDHC;LDHAL6A;LDHB L-lactate dehydrogenase A chain;L-lactate dehydrogenase;L-lactate dehydrogenase A-like 6A;L-lactate dehydrogenase C chain;L-lactate dehydrogenase B chain 0 ;; 120.63 0.0022297 35046000.0 44155.0 43948.3 44626.0 52339.0 58688.0 48377.0 46549.0 47930.0 41983.0 33837.3 False True 51629.56939899748 48311.19677980379 45690.05308504747 49406.61551532744 47188.50769533305 45840.024957158734 42139.541734424354 46671.88828603281 42596.921950967255 39971.73463408058 1.291651960357438 1.2086339815388656 1.1430590516852714 1.236038815118184 1.180546907141211 1.1468109997426719 1.0542335007521906 1.1676222889321286 1.0656760918914034 1.0 15.286692561606886 -1.522878745280341 0.08508648080133202 0.8709440351034914 1.9370195014628158 0.746887341946322 0.0423881451658667 90.19936713534752 0.5578198522415903 0.9810864209253782 11.252303038086854 0.029999999999999766 1.522878745280341 1.0660754663593244 VIGSGCNLDSAR ddPTM_PC-9_Lapatinib_30min_R1 4 VIGSGCNLDSAR 12 0 P00338-3;P00338;P00338-4;P00338-2;P00338-5;F5H155;F5H245;G3XAP5;A0A087WUM2;F5H5G7;Q6ZMR3;P07864;A0A5F9ZHM4;P07195;A0A3B3IS95;A8MW50 P00338-3;A0A5F9ZHM4 LDHA;LDHC;LDHAL6A;LDHB L-lactate dehydrogenase A chain;L-lactate dehydrogenase;L-lactate dehydrogenase A-like 6A;L-lactate dehydrogenase C chain;L-lactate dehydrogenase B chain 0 ;;; 284.47 1.5699999999999995e-77 233042000.0 133188.0 151812.0 146106.0 137812.0 165979.0 149216.0 135053.0 126642.0 126180.0 119115.0 False True 131288.71469631194 151460.48864130155 134093.72866546997 147947.15420735496 156216.44154726944 142834.3795194852 142045.38352059602 132526.24964935097 111968.27966569467 139703.8690392394 0.9397643429577184 1.0841538583212753 0.9598426270342328 1.0590054178513857 1.118196959193679 1.0224081874165312 1.016760555720178 0.9486226155420763 0.8014687097480853 1.0 17.092012450563068 -7.859924648775987 3.289135410670596 0.894138944639205 1.0333418822289402 0.3771551572065117 0.06713560426938309 0.22699961408752145 4.768062810971193 0.04056513872303824 0.017566339413530606 1.3806237856470647e-08 7.859924648775987 0.13920293758973523 VIHDNFGIVEGLMTTVHAITAT(ph)QK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VIHDNFGIVEGLMTTVHAITATQK 24 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 VIHDNFGIVEGLMT(0.025)T(0.021)VHAIT(0.356)AT(0.597)QK 59.093999999999994 0.0036549 1581800.0 1185.7 2638.4 3152.4 2899.8 3074.3 4044.6 2113.0 4411.1 4008.1 2623.9 True False 1386.4155913575203 2900.3229154218525 3227.5651715435733 2737.333607278446 2471.9129840472056 3832.494055888628 1912.8413432047673 4295.313298946784 4066.710879919773 3099.5922992190276 0.44728966183934615 0.9357110985701627 1.041287001634631 0.8831269867227841 0.7974961689864916 1.2364510186885747 0.6171267568598381 1.3857671862293082 1.3120147707633745 1.0 11.597862749653071 -4.141157575548252 0.3892573266362175 1.1288124052589303 8.982369320761047e-20 0.3284944223512638 0.23218906517622012 13.067283374861365 1.068436787357552 0.19289309701640628 7.590975715287877 7.225076078024651e-05 4.141157575548252 -1.1288124052589303 VIISAPSADAPMFVMGVNHEK ddPTM_PC-9_AZD4547_30min_R2 5 VIISAPSADAPMFVMGVNHEK 21 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ;;;; 128.74 1.0956e-05 63863100.0 220262.0 205796.0 275598.0 343569.0 314953.0 298033.0 264513.0 310505.0 270161.0 288862.0 False True 290300.7342657887 272315.5324398776 271943.39044746576 264364.47513813636 271227.2124345095 279396.94939605665 288054.14457042096 262523.58694507094 284441.158915387 278749.02930275025 1.0414412383495408 0.9769201102548588 0.9755850670680081 0.9483960385419288 0.9730158096440533 1.0023243851106032 1.0333816956814024 0.9417919323404825 1.0204202670297176 1.0 18.088607255532366 -6.767663462198021 24.780005784904084 0.9980580308659001 0.9803875557040438 0.06089828529337804 0.03126678318226955 418.6474902564146 1666755.6629678227 0.010994563523554761 0.009931349421801424 1.7074049564299494e-07 6.767663462198021 -0.01767047516185627 VIISAPSADAPMFVMGVNHEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 VIISAPSADAPMFVMGVNHEK 21 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ;;;; 133.24 2.3629e-05 124403400.0 292545.1 270941.5 327158.0 344419.9 353604.0 313951.7 323058.1 295792.8 273243.0 273837.8 False True 342067.207400899 297838.781530007 334958.68747362477 325123.1696273811 284317.83456755243 297487.52017161896 292455.6980299009 288028.5524183783 277238.6619500312 323482.4254411685 1.0574522153232417 0.9207263149576413 1.0354772350207428 1.0050721277484393 0.8789282267183356 0.9196404403296488 0.9040852764444528 0.8903993842186702 0.8570439694580947 1.0 18.303327808238485 -6.25413272499207 24.82619234643852 0.9032208491963566 1.0008848085870172 0.48561777285619656 0.048335087210609126 426.53718961226764 1449266.144347198 0.013590076196687001 0.01718150547873952 5.570154930847773e-07 6.25413272499207 0.09766395939066064 VIISAPSADAPMFVMGVNHEK ddPTM_PC-9_Lapatinib_30min_R1 6 VIISAPSADAPMFVMGVNHEK 21 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ;;;;; 111.82 1.498e-05 150132300.0 468416.0 446741.0 453012.0 434189.0 433394.0 430330.0 450385.0 429068.0 421291.0 425748.0 False True 461736.3019430256 445706.598662186 415767.10203689 466120.7074720443 407902.6170053877 411925.7890482257 473703.7315492704 449004.0656697447 373840.77118909627 499337.97452644963 0.9246969497581596 0.8925950386306484 0.8326366574286391 0.9334773865618629 0.8168868337967381 0.824943845776757 0.9486635419597526 0.8991987162513738 0.7486728233390031 1.0 18.929657101869324 -10.342580080486762 4.832415184021465 1.0000002300196655 0.870991688327897 0.30206010597505084 0.05963617012342987 27038461.936198518 61.57509009367823 76.78220191485511 0.014172150333208745 4.543807452487112e-11 10.342580080486762 -0.12900854169176856 VILAS(ph)PETSSAK ddPTM_PC-9_AZD4547_30min_R2 2 VILASPETSSAK 12 0 C9JKS0;P49116;P49116-2 C9JKS0 NR2C2 Nuclear receptor subfamily 2 group C member 2 1 VILAS(0.893)PET(0.079)S(0.022)S(0.007)AK;VILAS(0.376)PET(0.335)S(0.1)S(0.189)AK 96.23 0.0043487 18195500.0 88945.0 85526.0 99561.0 137621.0 125646.0 117222.0 96583.0 116555.0 106955.0 119913.0 True False 117227.65982907008 113170.6069479142 98240.7560879982 105894.60467325468 108202.22170783044 109892.08980919716 105178.69989393702 98544.10291744953 112608.42294703989 115714.88236867674 1.0130733180505989 0.9780125480086799 0.8489898107919723 0.9151338402252022 0.9350761068320462 0.949679829938143 0.9089470406998245 0.8516113130848654 0.9731541928052139 1.0 16.82021489928608 -5.019322694318719 18.600723137127712 0.9178407463964408 1.0043093204443385 0.3012617875279199 0.04517801166358243 25.822943608206398 24865.074837019984 0.011030491217169045 0.030765931561234593 9.564831104701758e-06 5.019322694318719 0.08646857404789776 VILAS(ph)PETSSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VILASPETSSAK 12 0 C9JKS0;P49116;P49116-2 C9JKS0 NR2C2 Nuclear receptor subfamily 2 group C member 2 1 VILAS(0.998)PET(0.002)SSAK;VILAS(0.997)PET(0.001)S(0.002)SAK;VILAS(0.948)PET(0.038)S(0.008)S(0.006)AK 119.01 0.001684 8045600.0 83181.0 80520.0 76768.0 91528.0 99430.0 93629.0 97323.0 79993.0 83488.0 64757.0 True False 97261.90040036263 88513.4934618584 78598.44026426117 86399.98289777986 79947.40526422708 88718.93041556561 88103.86088249771 77893.26850958959 84708.85405622183 76496.93148387005 1.2714483903301537 1.1570855424510997 1.0274718049420615 1.1294568451546052 1.0451060416859281 1.159771100547643 1.151730653419413 1.018253503750199 1.1073496990409781 1.0 16.223114257788843 -4.886885002685609 3.2147135245831784 1.0864492687357348 1.2789534664643574 0.539574856642968 0.054420044023573026 0.21707050570002343 3.815468189937351 0.013510744137134682 0.09153198896602975 1.297522797991857e-05 4.886885002685609 0.1925041977286226 VILAS(ph)PETSSAK ddPTM_PC-9_Lapatinib_30min_R1 1 VILASPETSSAK 12 0 C9JKS0;P49116;P49116-2 C9JKS0 NR2C2 Nuclear receptor subfamily 2 group C member 2 1 VILAS(0.652)PET(0.331)S(0.014)S(0.003)AK 107.53 0.0015407 7730300.0 96434.0 84871.0 75716.0 74797.0 85576.0 66885.0 72961.0 74972.0 85952.0 64557.0 True False 95058.83347617011 84674.4864139587 69490.92275221222 80297.82089547745 80542.5879288894 64024.48446655026 76738.56357908521 78455.47281874197 76271.18064531451 75715.59143320461 1.2554723759904838 1.1183229875270475 0.9177888125395717 1.0605189680954314 1.063751684485528 0.8455918160928836 1.0135107198731064 1.036186488590721 1.007337844182331 1.0 16.20830279161309 -4.959896327827951 3.3508623576634293 0.9949463926292694 1.2524621484542287 0.6296398261869061 0.06353582804689073 0.16354684268764996 3.5668094949011255 0.01661671305143171 0.08664307469751462 1.0967399720805636e-05 4.959896327827951 0.2575157558249592 VILASPET(ph)SSAK ddPTM_PC-9_Lapatinib_30min_R1 1 VILASPETSSAK 12 0 C9JKS0;P49116;P49116-2 C9JKS0 NR2C2 Nuclear receptor subfamily 2 group C member 2 1 VILAS(0.079)PET(0.688)S(0.183)S(0.049)AK 122.46 0.00097762 8490900.0 100020.0 86558.0 82104.0 80448.0 76482.0 76523.0 77727.0 77852.0 74980.0 67279.0 True False 98593.69645857842 86357.58026910757 75353.72605060514 86364.414286661 71983.47912939735 73250.28967382565 81751.3237388682 81469.28813269903 66534.96282559661 78908.08550636779 1.2494752068293689 1.0944072424889666 0.954955700256144 1.0944938498056895 0.9122446536050907 0.9282989088350704 1.0360322800161077 1.032458050526705 0.8431957561589467 1.0 16.2678855165725 -2.8248999540667254 0.8041459102789943 0.9694358631366138 7.876000037186539 0.6144971825751332 0.06795011835315333 33.18096633877275 1.134882942080465 0.023945018227122247 379.5374930634145 0.0014965803750398798 2.8248999540667254 6.906564174049925 VILGS(ph)PRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VILGSPRPR 9 1 A0A1C7CYW6;A0A1B0GWB1;A0A1B0GTQ2;P0DI83 A0A1C7CYW6 RAB34 Ras-related protein Rab-34, isoform NARR 1 VILGS(1)PRPR 73.885 0.019225 0.0 7676.9 5901.2 6991.3 6503.7 8825.4 7829.2 7392.3 6842.2 6717.0 6624.5 True False 8976.447544313523 6487.032136327866 7157.999106652896 6139.318774279888 7096.126223663992 7418.622969481102 6692.047828382676 6662.59949991015 6815.2234176844695 7825.469410486858 1.1470810341785054 0.8289639631885392 0.9147053973606377 0.7845304162907633 0.9067987939681321 0.9480099634073652 0.8551624800187333 0.8513993411029946 0.8709028251457268 1.0 12.933961579310504 -4.754807533796803 24.9994853401697 0.8794383062218901 1.147081485860429 0.6436208719901104 0.05850905813816206 134.18706185614002 505787.1805234342 0.013823847479068634 0.12999377435530565 1.758702845286512e-05 4.754807533796803 0.2676431796385389 VILHLK ddPTM_PC-9_AZD4547_30min_R2 1 VILHLK 6 0 P07900;P07900-2;G3V2J8;Q14568;Q58FF6;P08238;Q58FF7 P07900;P08238 HSP90AA1;HSP90AA2P;HSP90AB4P;HSP90AB1;HSP90AB3P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2;Putative heat shock protein HSP 90-beta 4;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 89.775 0.031674 10682000.0 105930.0 120580.0 130310.0 121290.0 123210.0 129550.0 125640.0 151840.0 117790.0 117150.0 False True 139613.53651912327 159555.1269295826 128582.00425695848 93328.46441181978 106104.41825940984 121449.21802035041 136821.7166030693 128376.61693608663 124016.13892694905 113048.61415768487 1.2349867139846982 1.4113850763975622 1.137404515880283 0.8255604467794836 0.9385733655382189 1.0743096580639904 1.210290967496733 1.1355877105845953 1.0970160036987824 1.0 16.786583780899626 -5.463012084357908 6.133285861146913 1.0450991540822065 1.315681306129838 0.5177309629443316 0.10794988372241146 0.19407847312716547 15.068259258874253 0.03185090197676873 0.06632456644938135 3.443403492694696e-06 5.463012084357908 0.2705821520476315 VILHLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VILHLK 6 0 P07900;P07900-2;G3V2J8;Q14568;Q58FF6;P08238;Q58FF7 P07900;P08238 HSP90AA1;HSP90AA2P;HSP90AB4P;HSP90AB1;HSP90AB3P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2;Putative heat shock protein HSP 90-beta 4;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 88.626 0.032498 12574000.0 123460.0 169060.0 148590.0 133090.0 147720.0 114990.0 148180.0 113700.0 109540.0 101220.0 False True 144359.33955384963 185843.15952138384 152132.94913071318 125633.3987836015 118775.32641689284 108959.72197167412 134143.31766970316 110715.49547510801 111141.8152706801 119570.38474292103 1.2073168440849746 1.5542574352416005 1.2723296781038413 1.0507066532713438 0.9933507086412946 0.9112601101513551 1.1218774444701693 0.9259441266593628 0.929509556313944 1.0 16.867500580734884 -5.725340513034372 2.8650932950978016 0.98322332584933 1.388014184979559 0.7453391175250977 0.09663811828005396 0.11540439174009882 1.9279512953077806 0.026606640831960213 0.04843675011172289 1.8821727739742054e-06 5.725340513034372 0.40479085913022905 VILHLK ddPTM_PC-9_Lapatinib_30min_R1 2 VILHLK 6 0 P07900;P07900-2;G3V2J8;Q14568;Q58FF6;P08238;Q58FF7 P07900;P08238 HSP90AA1;HSP90AA2P;HSP90AB4P;HSP90AB1;HSP90AB3P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2;Putative heat shock protein HSP 90-beta 4;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 ; 90.631 0.03106 42199000.0 217099.0 257810.0 259510.0 248970.0 261100.0 257340.0 269570.0 261620.0 231455.0 247150.0 False True 214003.12844891913 257213.05678479874 238174.08953756918 267280.084339573 245742.61134235057 246334.1680888395 283527.0155838596 273775.82029076543 205386.10057079856 289869.5481933261 0.7382739228136911 0.8873407309872116 0.8216595741844567 0.9220702416154205 0.8477696704396647 0.8498104392964692 0.9781193552444618 0.9444794115046984 0.7085466612512812 1.0 18.145044255652493 -14.522874742128698 0.017010441604394893 2.0490659149710284 6.712451320916503e-13 0.19613832638421802 0.08207835229569249 7920.723307324931 10.175024643679583 790.9576194370721 472.60825271832397 3.0000276529193182e-15 14.522874742128698 -2.049065914970357 VINAAHSFYNGTTTLPISDEDRT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 VINAAHSFYNGTTTLPISDEDRTPR 25 1 P49915-2;P49915 P49915-2 GMPS GMP synthase [glutamine-hydrolyzing] 1 VINAAHSFY(0.005)NGT(0.002)T(0.002)T(0.005)LPIS(0.026)DEDRT(0.96)PR;VINAAHSFYNGTTTLPIS(0.043)DEDRT(0.957)PR 113.29 3.0439e-08 22073800.0 18833.4 22117.8 37886.6 51005.0 50104.4 34124.8 32801.5 39002.9 39945.6 41391.0 True False 24822.029440944494 29266.946312847293 37384.19892933532 39246.585269394585 43148.268924898635 31990.970861450016 35720.76995507461 32975.8980024795 42057.04286544133 39941.913688439876 0.6214531841054118 0.7327377085920105 0.935964140850747 0.9825915096490098 1.080275453536588 0.8009373589605686 0.8943179396387569 0.8255963462267332 1.0529551286275405 1.0 15.28561583608401 -5.117288647547255 2.7651594590522395 0.9405003970640573 0.6299692797728376 0.6247309898359833 0.08541661571024019 0.19588839357236734 2.743459026398427 0.023489202789214486 0.09522765550696059 7.633282798408217e-06 5.117288647547255 -0.31053111729121974 VINAAHSFYNGTTTLPISDEDRT(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VINAAHSFYNGTTTLPISDEDRTPR 25 1 P49915-2;P49915 P49915-2 GMPS GMP synthase [glutamine-hydrolyzing] 1 VINAAHSFY(0.001)NGT(0.002)T(0.002)T(0.004)LPIS(0.298)DEDRT(0.693)PR;VINAAHSFY(0.001)NGT(0.003)T(0.003)T(0.003)LPIS(0.208)DEDRT(0.78)PR 55.247 0.0039515999999999996 17330700.0 27810.4 30630.0 37579.0 39797.0 44267.0 44845.0 47384.0 42769.0 42712.0 31556.0 True False 32518.151439562436 33670.7439733821 38475.025879151144 37567.30311361481 35593.199123318365 42493.24925488938 42895.44448954787 41646.35906750128 43336.582196834745 37276.853002841446 0.8723416495776541 0.9032614413779922 1.0321425436910774 1.0077917014816467 0.9548337978156379 1.13993660493954 1.1507260145130314 1.1172176756532202 1.16256010649642 1.0 15.185992449068623 -5.545734202522776 0.598476229754311 1.1220319817739541 0.8232512259157444 0.6243859354896424 0.06117692879289029 1.1140631889730963 0.5558662067601868 0.03718698194061456 0.20564034430819889 2.8462025110914722e-06 5.545734202522776 -0.29878075585820973 VINAAHSFYNGTTTLPISDEDRT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 VINAAHSFYNGTTTLPISDEDRTPR 25 1 P49915-2;P49915 P49915-2 GMPS GMP synthase [glutamine-hydrolyzing] 1 VINAAHSFYNGTTTLPIS(0.177)DEDRT(0.823)PR;VINAAHSFYNGT(0.002)T(0.002)T(0.002)LPIS(0.346)DEDRT(0.647)PR 62.67 0.0011359999999999999 11698500.0 30037.0 24686.5 28164.5 24970.7 24850.7 25384.3 22407.6 17290.5 27683.6 23472.1 True False 29608.666871888803 24629.339925984026 25848.92352811398 26807.12857781327 23389.030684355996 24298.672662693458 23567.755886771145 18093.879752073582 24565.581446768294 27529.221210392712 1.0755359421759112 0.8946617028412727 0.938963123241409 0.9737699578545709 0.8496074228037468 0.8826502020158975 0.8560996225303297 0.6572608652380932 0.8923456736761737 1.0 14.748676176849555 -6.325657100848977 1.1158639224630091 0.8282502624537109 0.9763026758017256 0.24331852553547795 0.0918557649704542 0.6328469912429524 1.6445745723131107 0.0395797084378466 0.05538215640326682 4.724359079295178e-07 6.325657100848977 0.14805241334801467 VINEPTAAALAYGLDK ddPTM_PC-9_Lapatinib_30min_R1 1 VINEPTAAALAYGLDK 16 0 P38646 P38646 HSPA9 Stress-70 protein, mitochondrial 0 138.55 7.3695e-05 3297800.0 10621.0 10515.0 9202.2 7655.0 9615.3 10193.0 10567.0 9030.3 13224.0 10532.0 False True 10469.542592347145 10490.653163539671 8445.630637519236 8217.974236331407 9049.746958407144 9757.069151043535 11114.10755527191 9449.880704730918 11734.573865106557 12352.442166992125 0.8475686387201702 0.8492776587590527 0.6837215283701089 0.665291456153607 0.7326281585506745 0.7898898872901524 0.8997498150584943 0.7650212465663384 0.9499800692419658 1.0 13.592508680784055 -8.245989320397932 0.8077083433489708 1.0019587144740805 0.7575149779698973 0.5496797823300503 0.07080015373253665 0.4983039889538124 0.7009011643717876 0.0732897164217105 0.028309408446910614 5.675585618950298e-09 8.245989320397932 -0.24444373650418316 VIPAKS(ph)PPPPTHSTQLGAPSR ddPTM_PC-9_AZD4547_30min_R2 2 VIPAKSPPPPTHSTQLGAPSR 21 1 Q14814-6;Q14814-3;Q14814-5;Q14814-4;Q14814-2;Q14814 Q14814-6 MEF2D Myocyte-specific enhancer factor 2D 1 VIPAKS(0.999)PPPPT(0.001)HSTQLGAPSR;VIPAKS(1)PPPPTHSTQLGAPSR 95.365 0.00014773 28843000.0 29416.0 17621.2 70746.0 171902.0 132558.0 93049.0 55389.0 134580.0 77879.0 119747.0 True False 38769.67610919021 23316.90829865287 69807.8618153848 132272.64975942494 114154.60981763493 87230.63132053716 60318.51369728909 113783.7533407434 81995.52494687038 115554.69397815006 0.3355093140268371 0.20178244168135484 0.6041110007057314 1.1446756960339148 0.9878837967345588 0.7548860917500364 0.521991029708361 0.9846744379095363 0.7095819488075034 1.0 16.81821633953404 -5.475872466392338 4.4942198816159955 0.8589177974396904 0.28306299015946573 0.663011979885033 0.1712943625998134 0.12974058903417943 5.679470840600597 0.04846495272369439 0.10129543157671154 3.342931931445578e-06 5.475872466392338 -0.5758548072802248 VIPAKS(ph)PPPPTHSTQLGAPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VIPAKSPPPPTHSTQLGAPSR 21 1 Q14814-6;Q14814-3;Q14814-5;Q14814-4;Q14814-2;Q14814 Q14814-6 MEF2D Myocyte-specific enhancer factor 2D 1 VIPAKS(0.958)PPPPT(0.018)HS(0.018)T(0.007)QLGAPSR 62.792 0.0027844000000000002 8328900.0 19563.0 18801.0 43545.0 46696.0 59243.0 50796.0 46126.0 38365.0 51303.0 31266.0 True False 22874.629513137545 20667.43902851965 44583.277945332135 44079.774510474606 47634.759429433914 48132.16833875261 41756.611356679176 37357.95940107758 52053.20931925951 36934.278298480196 0.6193333284673607 0.5595733822520661 1.207097579788548 1.1934651641017293 1.289716805740158 1.3031842114194823 1.1305652440052527 1.0114712164990325 1.4093468646821088 1.0 15.172672766991504 -5.262663729432159 24.998752539818916 1.1986765814741986 0.5894533076380902 0.8011693386606162 0.12026355771057466 39.711665225545865 810852.6536469455 0.030422659345002583 0.0695711021740352 5.4618060045760876e-06 5.262663729432159 -0.6092232738361084 VIPAKS(ph)PPPPTHSTQLGAPSR ddPTM_PC-9_Lapatinib_30min_R1 1 VIPAKSPPPPTHSTQLGAPSR 21 1 Q14814-6;Q14814-3;Q14814-5;Q14814-4;Q14814-2;Q14814 Q14814-6 MEF2D Myocyte-specific enhancer factor 2D 1 VIPAKS(0.991)PPPPT(0.005)HS(0.003)T(0.001)QLGAPSR 61.303999999999995 0.0036911 6727100.0 16159.0 8066.6 43767.0 19872.0 22281.0 26668.0 11411.0 17555.0 30252.0 13133.0 True False 15928.569696802322 8047.922283310429 40168.64620550571 21333.453171048703 20970.475386131428 25527.471806144298 12001.805745548183 18370.669387678292 26844.701192317258 15403.021551377484 1.034119808485098 0.5224898411305999 2.6078419790247875 1.3850174201139687 1.3614520577137055 1.6573028688557143 0.7791851556862146 1.1926666028741233 1.7428204656323778 1.0 13.910925766157849 -7.222736697441961 24.942550725288676 1.1947225736090994 1.4355214386554462 0.04793115222657962 0.5419698704107017 2110.3840099427457 1360071.7444508637 0.21348131673046622 0.16535893451879927 5.98774507976391e-08 7.222736697441961 0.24079886504634684 VIPELNGK ddPTM_PC-9_AZD4547_30min_R2 2 VIPELNGK 8 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 144.38 0.0073955 41529000.0 344190.0 334850.0 426760.0 572910.0 476150.0 499820.0 395390.0 523200.0 393060.0 428430.0 False True 453635.26040325523 443083.7141513583 421100.8835599697 440834.4508712644 410044.79144726763 468566.17638696684 430578.94402807666 442351.46193993883 413836.3491521062 413430.7961039426 1.097245934938056 1.0717240184496573 1.0185522886255884 1.066283535299175 0.9918099844312912 1.1333606030382952 1.0414776743429213 1.0699528581531337 1.0009809454254144 1.0 18.657286332313966 -8.268008186160186 23.944160285250735 1.0004904476795435 1.0598142935200618 0.30005693724654714 0.03709517866191784 393.615739031182 1434746.3133488582 0.03161768092320899 0.00899611552986546 5.395004531969852e-09 8.268008186160186 0.05932384584051831 VIPELNGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VIPELNGK 8 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 145.34 0.0066281000000000005 69077000.0 568750.0 552600.0 593550.0 663080.0 709430.0 656330.0 719780.0 598510.0 576950.0 536700.0 False True 665028.1416754569 607458.4759938279 607702.4830509099 625929.7773343642 570422.2841858657 621910.8993970689 651597.2276440719 582799.7466737633 585386.8022678366 633999.4614851378 1.048941177517146 0.9581372113011928 0.9585220808033063 0.9872717807490398 0.8997204553607298 0.9809328511734827 1.0277567525336875 0.9192432834383807 0.9233238162325462 1.0 19.274122089386587 -4.760473084148512 24.720218290020323 0.9605678663036618 1.0489412935796618 0.3283417857685005 0.037422470424164085 25.339721002561863 647861.461322555 0.00938324186762797 0.055803237878219336 1.7359088442908746e-05 4.760473084148512 0.08837342727600006 VIPELNGK ddPTM_PC-9_Lapatinib_30min_R1 2 VIPELNGK 8 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 143.12 0.008498899999999998 204089000.0 940940.0 908420.0 930660.0 901450.0 908000.0 856950.0 872540.0 756140.0 809620.0 824180.0 False True 927522.0230527387 906316.6093031568 854144.7272514896 967745.6401490457 854593.2251966853 820300.2461480179 917715.8518289917 791273.0248247827 718432.0699234398 966638.4148491821 0.9595335844349343 0.937596308382347 0.88362381851414 1.0011454389592374 0.8840877954659204 0.8486112630605558 0.949388972889285 0.8185822254418055 0.743227311150811 1.0 19.88261680399571 -6.498933096942981 20.275145887340404 0.8655610345998302 0.9407595585794924 0.1953080772828334 0.07059335617449303 114.19709252325137 96691.88306685466 0.021821488442195516 0.024509990086990653 3.1700557724644487e-07 6.498933096942981 0.0751985239796622 VIPS(ph)PFK ddPTM_PC-9_AZD4547_30min_R2 2 VIPSPFK 7 0 P34897-3;P34897-2;P34897;G3V2Y4;G3V4W5;H0YIZ0 P34897-3 SHMT2 Serine hydroxymethyltransferase, mitochondrial;Serine hydroxymethyltransferase 1 VIPS(1)PFK;VIPS(1)PFK 85.86200000000001 0.019 15109600.0 236450.0 206725.0 228330.0 269070.0 271500.0 255860.0 256980.0 304040.0 225750.0 252790.0 True False 311636.1815344721 273544.8135222921 225302.19501182807 207040.06859006017 233806.9114311309 239861.0337528891 279850.72216377466 257057.60414415004 237682.6841222406 243939.89904328817 1.2775121362133997 1.1213615099256495 0.9235971478853783 0.8487339275044958 0.9584611305821721 0.9832792203883168 1.1472117651164313 1.053774331924824 0.9743493584051325 1.0 17.89616622045189 -4.952294585163086 3.2414175623195436 0.9884470856107643 1.2765053876272356 0.6026583717970129 0.0744176253084678 0.2055338136247474 4.083631681769127 0.022098287121904186 0.1213025792241851 1.1161059280458924e-05 4.952294585163086 0.2880583020164713 VIPS(ph)PFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VIPSPFK 7 0 P34897-3;P34897-2;P34897;G3V2Y4;G3V4W5;H0YIZ0 P34897-3 SHMT2 Serine hydroxymethyltransferase, mitochondrial;Serine hydroxymethyltransferase 1 VIPS(1)PFK 69.812 0.045593 6954600.0 127760.0 124190.0 102130.0 120580.0 150070.0 122930.0 126070.0 127200.0 100810.0 97498.0 True False 149387.2446249783 136518.76245688283 104565.16653018181 113824.29352563457 120664.86078650889 116483.33439410313 114127.73693224115 123861.13477954041 102284.1555362173 115173.61560625659 1.2970613437689382 1.1853301794709543 0.9078916727565294 0.9882844514907395 1.0476779786008037 1.011371691172083 0.9909191122592611 1.075429768593736 0.8880866941426548 1.0 16.813450731202536 -5.069785519425929 4.209887976720706 0.9950033250489339 1.2782887701280021 0.7828768504949826 0.05444864884712786 0.08724768747804777 2.924456330294058 0.013742188872967574 0.044507079883189145 8.515584848526654e-06 5.069785519425929 0.2832854450790683 VIPS(ph)PFK ddPTM_PC-9_Lapatinib_30min_R1 1 VIPSPFK 7 0 P34897-3;P34897-2;P34897;G3V2Y4;G3V4W5;H0YIZ0 P34897-3 SHMT2 Serine hydroxymethyltransferase, mitochondrial;Serine hydroxymethyltransferase 1 VIPS(1)PFK 83.647 0.020712 4469100.0 143230.0 132610.0 101640.0 101470.0 89270.0 82151.0 62532.0 63596.0 108650.0 69262.0 True False 141187.51393483454 132302.94969253417 93283.55154174598 108932.44229399692 84019.31411157278 78637.59323333447 65769.60098857408 66550.90232861234 96412.69286477812 81233.84441418617 1.7380380671750952 1.6286678372374261 1.148333582073527 1.3409736185645011 1.0342895220271044 0.9680397844079098 0.809632997956311 0.8192509268586371 1.18685374993703 1.0 16.309793301487936 -5.1140531632507935 0.6864745565535125 0.9312214325879639 2.0790977620326205 0.806340976967006 0.13230997156666557 0.8911279453709752 0.4285925163475472 0.06252695997675911 0.7437770172470783 7.69036294554633e-06 5.1140531632507935 1.1478763294446566 VIQEIVDK ddPTM_PC-9_Lapatinib_30min_R1 1 VIQEIVDK 8 0 B4DXZ6;P51114;P51114-3;P51114-2;E7EU85;E9PFF5;P51116 B4DXZ6;P51116 FXR1;FXR2 Fragile X mental retardation syndrome-related protein 1;Fragile X mental retardation syndrome-related protein 2 0 113.66 0.007060600000000001 0.0 19603.0 17123.0 13414.0 17063.0 15499.0 13623.0 14742.0 12725.0 15698.0 11011.0 False True 19323.45762525008 17083.352745533994 12311.1526995374 18317.869940499386 14587.37929220641 13040.376046764062 15505.26862684001 13316.249954896408 13929.925932731601 12914.236678764752 1.4962911169983584 1.3228310097200433 0.9533008419909929 1.4184245183162845 1.129557995184714 1.0097674660250517 1.200633766634908 1.03112946480164 1.07864880280822 1.0 13.656674752211284 -1.5228787452803376 0.5631073687407558 1.0853520234726677 20.88989032232422 0.4887936841354653 0.1284833664158016 127.29326986915933 1.1176958906966994 0.06173811802833031 3064.196473028621 0.029999999999999995 1.5228787452803376 19.804538298851554 VIQLMPS(ph)PIMHPLILNPR ddPTM_PC-9_AZD4547_30min_R2 2 VIQLMPSPIMHPLILNPR 18 0 P41212 P41212 ETV6 Transcription factor ETV6 1 VIQLMPS(1)PIMHPLILNPR;VIQLMPS(1)PIMHPLILNPR 69.779 0.0054210000000000005 18731800.0 17591.3 17771.4 26651.2 35652.0 31620.0 28962.0 24918.0 35836.0 25810.0 25335.0 True False 23184.96747822946 23515.657511331792 26297.787674415267 27432.98221790916 27230.10880092957 27151.0015616008 27135.653727437726 30298.3696293572 27174.263907840694 24448.029361373825 0.9483368632917337 0.9618631082178298 1.0756608348959174 1.122093802016262 1.113795651928954 1.1105599212220139 1.1099321473455919 1.2392970076036682 1.1115114231159313 1.0 14.577430560671669 -5.346394802338642 2.2058219093568914 1.1252429063970688 0.9435011071264097 0.5706681623663399 0.05435596620214338 0.21765483927237048 1.9931296261398443 0.015027372509746683 0.047313869136097135 4.5040706863355415e-06 5.346394802338642 -0.18174179927065914 VIQLMPS(ph)PIMHPLILNPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VIQLMPSPIMHPLILNPR 18 0 P41212 P41212 ETV6 Transcription factor ETV6 1 VIQLMPS(1)PIMHPLILNPR;VIQLMPS(1)PIMHPLILNPR;VIQLMPS(1)PIMHPLILNPR 71.148 0.0047334 24816100.0 39275.2 38517.3 45751.0 50701.0 62036.0 53583.0 51268.0 52923.0 56559.0 49241.0 True False 45923.71563944072 42341.04299203233 46841.877351633724 47860.38734485979 49880.491129152164 50773.0131525195 46411.52389182298 51533.827326553626 57386.06837588447 58168.0035084585 0.7895013215085287 0.7279095110402973 0.8052859738399344 0.82279577186967 0.8575245516531917 0.8728684171726186 0.7978875170620915 0.8859480164049267 0.9865572980777941 1.0 15.827938167162516 -7.534057281051632 0.2663456520930516 1.0325017230182352 0.7215522374212542 0.7756510142902557 0.0387202027843238 0.9880667074570153 0.24276822496952888 0.08641966714060512 0.11562657867337611 2.923766723673793e-08 7.534057281051632 -0.310949485596981 VIQLMPS(ph)PIMHPLILNPR ddPTM_PC-9_Lapatinib_30min_R1 3 VIQLMPSPIMHPLILNPR 18 0 P41212 P41212 ETV6 Transcription factor ETV6 1 VIQLMPS(1)PIMHPLILNPR;VIQLMPS(1)PIMHPLILNPR;VIQLMPS(1)PIMHPLILNPR 85.61 0.00092893 19064300.0 47648.0 43855.0 48293.0 37605.8 44775.0 42385.0 38884.0 40223.0 45248.6 32399.7 True False 46968.53078242697 43753.45644194318 44322.53595637094 40371.455981271305 42141.422531036944 40572.29235426076 40897.22325912677 42091.907421280805 40152.22617911829 37999.944975113445 1.2360157577382584 1.1514084157384377 1.1663842141192107 1.0624082747412131 1.1089864092865342 1.0676934501045192 1.0762442757722617 1.107683378195606 1.056639061067441 1.0 15.213709709048082 -1.5228787452803376 0.3231704719191113 1.0501714972496246 2.817834156793341 0.777581769308352 0.03000549827638562 26.90561482009052 0.38377256358312817 0.027222321095447737 28.203878706470373 0.029999999999999995 1.5228787452803376 1.7676626595437164 VIQPMGMS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 VIQPMGMSPR 10 0 H0YE35;Q9NPQ8-2;Q9NPQ8-4;Q9NPQ8;Q9NPQ8-3 H0YE35 RIC8A Synembryn-A 1 VIQPMGMS(1)PR 73.95100000000001 0.01591 16616000.0 118290.0 119320.0 121320.0 103660.0 103640.0 104050.0 105280.0 92043.0 116120.0 96242.0 True False 116603.16290827094 119043.7218709991 111345.53790874314 111283.50219962317 97544.09896407979 99600.02405239662 110730.88326100366 96319.65379949156 103041.34280219098 112877.30146559616 1.0330080662303074 1.0546294102121356 0.986429835432238 0.9858802501009579 0.8641604441067386 0.8823742484909926 0.9809845010757393 0.8533128675905562 0.9128615006232845 1.0 16.784395877683615 -5.835885808578326 1.915508987137823 0.9108253267595646 1.0382949589022028 0.5247995153909184 0.04690292775594304 0.2428222352717488 1.819100226394363 0.014262145388856791 0.026617958918650153 1.459197884713676e-06 5.835885808578326 0.12746963214263818 VIQYLAHVAS(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VIQYLAHVASSPK 13 0 Q7Z406;Q7Z406-6;Q7Z406-2;Q7Z406-4;Q7Z406-5;M0QY43;A0A2R8Y4C3 Q7Z406 MYH14 Myosin-14 1 VIQYLAHVAS(0.614)S(0.386)PK 83.37 0.0053662 3181000.0 18311.0 14214.0 14580.0 20731.0 24283.0 14900.0 19119.0 17978.0 17402.0 12145.0 True False 21410.6906412647 15625.071982946562 14927.64249495792 19569.50928080883 19524.92046697406 14118.61777004909 17307.90991042686 17506.096549265545 17656.471328650463 14346.792360232903 1.4923677783622098 1.0890986354731704 1.040486411187984 1.3640337707160588 1.360925841590496 0.9840957766408972 1.2063957904905434 1.220209793918099 1.2306912155215601 1.0 13.808440596362026 -6.741769270640037 24.999969360296642 1.146923846306241 1.2519086204599272 0.17616460982209858 0.1474816099214214 606.4329070500055 770751.7903207127 0.05021334990216014 0.05014497515057495 1.8123026661608756e-07 6.741769270640037 0.10498477415368623 VIS(ph)DCECVPQK ddPTM_PC-9_Lapatinib_30min_R1 2 VISDCECVPQK 11 0 Q5VY60;Q7Z4H7-3;Q7Z4H7 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 VIS(1)DCECVPQK;VIS(1)DCECVPQK 104.87 0.0026294 9482900.0 17934.9 29023.0 42506.0 28012.0 37877.0 36325.0 33071.0 32015.0 36421.0 26885.0 True False 17679.145037142145 28955.79902666781 39011.32075790495 30072.095925292688 35649.14932904717 34771.46442771083 34783.25456235423 33502.53377650359 32318.883449867346 31532.03642798933 0.5606724791631059 0.9182977792377935 1.2371963620870567 0.9536997711508183 1.130569204131811 1.10273450010498 1.1031084098164674 1.0624919152625725 1.0249538916928174 1.0 14.944530725900824 -4.837856186109672 3.2208925845195955 1.0789181352150852 0.5182391013449394 0.8131130700429492 0.07487395331690563 0.1086175268324533 1.824419447264064 0.017750852670975873 0.1427227078455618 1.452592554855979e-05 4.837856186109672 -0.5606790338701457 VIS(ph)PSEDR ddPTM_PC-9_AZD4547_30min_R2 1 VISPSEDR 8 0 P17252 P17252 PRKCA Protein kinase C alpha type 1 VIS(0.975)PS(0.025)EDR 74.165 0.028172000000000003 7790400.0 23708.0 25375.0 35205.0 55680.0 44986.0 36955.0 24440.0 38891.0 23423.0 29508.0 True False 31246.65084296581 33576.97251482967 34738.15869746164 42843.836247424595 38740.47041488353 34644.19800804357 26615.112653446435 32881.28957627332 24661.091960997772 28474.93390153617 1.097338836712106 1.1791764866227927 1.2199557272927535 1.504615827926935 1.3605113377556797 1.216655958810657 0.9346856693497223 1.154745071225589 0.8660631854765202 1.0 14.797404872579003 -7.140177373667121 4.713634363327548 1.0028085540502671 1.2779514462221724 0.5452807118274745 0.1229458159387205 0.19828837408161645 6.779104652099126 0.05144621419478481 0.039499685880666456 7.241401478283494e-08 7.140177373667121 0.27514289217190524 VIS(ph)PSEDR ddPTM_PC-9_Lapatinib_30min_R1 1 VISPSEDR 8 0 P17252 P17252 PRKCA Protein kinase C alpha type 1 VIS(0.967)PS(0.033)EDR 82.287 0.016683 6199900.0 37383.0 37487.0 42700.0 34049.0 38217.0 38645.0 38023.0 32347.0 35149.0 31094.0 True False 36849.91156479742 37400.201154694405 39189.3708267666 36553.07704413431 35969.15119751287 36992.24343589497 39991.64489203215 33849.95970852919 31190.14948462116 36468.55646984935 1.0104570932294334 1.0255465193862363 1.0746071306432627 1.002317628731887 0.9863058667334593 1.014359958735372 1.0966061934778126 0.9281957660297001 0.8552614225465122 1.0 15.154365474342578 -7.872311668606423 7.899719284601536 0.9161919761197718 1.0280673011960118 0.5127726482890841 0.045323353371600136 0.17570769558172672 11.504076664596383 0.024315742210178643 0.01163066681617607 1.3418016802962437e-08 7.872311668606423 0.11187532507623998 VIS(ph)PSQK ddPTM_PC-9_AZD4547_30min_R2 1 VISPSQK 7 0 E7EWD6;Q76L83;A0A5F9ZHC8 E7EWD6 ASXL2 Putative Polycomb group protein ASXL2 1 VIS(0.904)PS(0.096)QK 76.1 0.031751 4310600.0 53774.0 43834.0 57981.0 74288.0 63915.0 65202.0 60993.0 74326.0 60825.0 62778.0 True False 70873.01343131615 58002.4832794106 57212.13405588762 57162.04933815879 55041.50550320724 61124.90863267367 66421.2588409026 62840.62454156712 64040.08532330143 60580.161328136026 1.1699046664373884 0.9574501290156148 0.9444037916306415 0.9435770404858641 0.9085731086959586 1.008992173222963 1.0964193126051271 1.037313588539112 1.0571131525455093 1.0 15.886557799660151 -7.004638454432211 24.929037886649034 1.0510902369582273 0.976736122342495 0.14605535501963252 0.07026246912859993 332.7519428428826 1788359.3633379696 0.025517743581174285 0.02193519561395381 9.89376397311841e-08 7.004638454432211 -0.07435411461573238 VISELNGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VISELNGK 8 0 P05387 P05387 RPLP2 60S acidic ribosomal protein P2 0 95.741 0.025793 0.0 36427.0 37535.0 43224.0 52457.0 56268.0 50117.0 53807.0 51969.0 47276.0 40219.0 False True 42593.371633954965 41261.22673982691 44254.62408793287 49518.00435788863 45242.68932321774 47488.77629406379 48710.01143105488 50604.86881570703 47967.32206259502 47510.3863265712 0.8965065310389554 0.8684675063724053 0.9314726212441368 1.04225640300034 0.9522694471948505 0.9995451514041821 1.0252497442609252 1.0651327578745697 1.0096175967268082 1.0 15.535955317495057 -5.581941304116037 4.049959798832792 1.013287153491523 0.8849169664791925 0.7765308369604955 0.02889266238673412 0.09866463417914 3.291438315383032 0.008526829011609815 0.015941177467679715 2.6185368855022226e-06 5.581941304116037 -0.1283701870123306 VISELNGK ddPTM_PC-9_Lapatinib_30min_R1 2 VISELNGK 8 0 P05387 P05387 RPLP2 60S acidic ribosomal protein P2 0 ; 134.81 0.017697 35938000.0 218246.0 194700.0 216516.0 205452.0 219978.0 198483.0 205639.0 165656.0 198029.0 194967.0 False True 215133.7720185849 194249.1841123322 198714.89025592967 220561.62544778062 207039.32653338788 189994.34477647138 216285.98122064554 173352.98251696047 175724.88868218282 228666.78617280195 0.9408177532875708 0.8494857839368916 0.8690151008890384 0.9645547092313778 0.9054193221438362 0.8308786245541315 0.9458565664066302 0.7581030258848296 0.7684757879501953 1.0 17.802887304097112 -7.753875800779602 24.999280018993964 0.8224670510543854 0.8975937306417665 0.09831461889843118 0.07409480356342085 284.60025011178953 940675.0092098791 0.03411665624729483 0.01921076962325933 1.7624800070989408e-08 7.753875800779602 0.07512667958738106 VISFIENTS(ph)TPVDR ddPTM_PC-9_AZD4547_30min_R2 2 VISFIENTSTPVDR 14 0 Q9NUY8-2;Q9NUY8;E9PGE5 Q9NUY8-2 TBC1D23 TBC1 domain family member 23 1 VISFIENT(0.002)S(0.916)T(0.082)PVDR;VISFIENT(0.101)S(0.449)T(0.449)PVDR 209.79 4.0185e-11 4907800.0 18945.8 18883.3 20655.0 26533.0 29712.0 25791.0 21306.0 26244.0 20108.1 18634.0 True False 24970.17030287926 24986.957441942173 20381.101204262755 20416.226780763594 25587.001666452234 24178.284692881916 23202.192724808923 22188.59282712494 21170.973114500237 17981.629331748187 1.3886489284256447 1.3895825000588489 1.1334401809894994 1.1353935955468122 1.4229523473312886 1.3446103379626992 1.2903276058440023 1.2339589710009748 1.1773667849509597 1.0 14.134236130231262 -8.585888541873581 1.2809123844956616 1.0016365385225976 1.2974206700766298 0.48881978325402875 0.09429023567951327 0.5093642061192339 1.807784672264503 0.09790933430074553 0.029894469884499637 2.594845222472865e-09 8.585888541873581 0.29578413155403216 VISFIENTS(ph)TPVDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VISFIENTSTPVDR 14 0 Q9NUY8-2;Q9NUY8;E9PGE5 Q9NUY8-2 TBC1D23 TBC1 domain family member 23 1 VISFIENT(0.188)S(0.624)T(0.188)PVDR;VISFIENT(0.05)S(0.475)T(0.475)PVDR;VISFIENT(0.013)S(0.817)T(0.17)PVDR 170.26 2.9224e-05 7791900.0 30832.3 37744.0 37725.0 35272.0 41713.0 31153.4 33711.0 30636.3 27379.2 22782.5 True False 36051.59942431684 41490.97487859401 38624.50707285921 33295.82419336691 33539.637089275966 29519.66086157366 30517.650033495465 29832.129586843042 27779.569003642475 26912.786903829234 1.3395713923327393 1.5416825848195805 1.4351730725948564 1.2371748905955733 1.2462342606556234 1.0968637684034688 1.1339461105439557 1.1084741871381012 1.0322070732737796 1.0 14.716004173877876 -6.225169604420784 0.8967273423316355 1.0636394208362039 1.4714405542272513 0.847248990947923 0.0658238099063327 0.22128002144400638 0.378183594756677 0.032168779786931265 0.05477381534334929 5.954295658365487e-07 6.225169604420784 0.4078011333910474 VISFIENTS(ph)TPVDR ddPTM_PC-9_Lapatinib_30min_R1 1 VISFIENTSTPVDR 14 0 Q9NUY8-2;Q9NUY8;E9PGE5 Q9NUY8-2 TBC1D23 TBC1 domain family member 23 1 VISFIENT(0.06)S(0.702)T(0.238)PVDR 180.3 4.7666e-05 1852500.0 16882.0 17055.0 18383.0 14990.0 13760.0 15399.0 13709.0 13299.0 15245.0 12020.0 True False 16641.25958422036 17015.510195356073 16871.620700432086 16092.414605174103 12950.663853200856 14740.420666822263 14418.784941347834 13916.920090386417 13527.947563033087 14097.640984356762 1.180428669072087 1.2069757070872411 1.1967690707369716 1.1414969797451087 0.918640492233514 1.0455948398160197 1.0227799783912377 0.9871807705863074 0.959589450323226 1.0 13.783166150336541 -6.095856916909673 4.7416573574261145 0.993424312103754 1.19262410040887 0.8912054822938281 0.03325652772068109 0.06939217536446379 2.5681245941535535 0.010100198683255526 0.013366353427485518 8.019422285504513e-07 6.095856916909673 0.19919978830511598 VISFIENTST(ph)PVDR ddPTM_PC-9_AZD4547_30min_R2 1 VISFIENTSTPVDR 14 0 Q9NUY8-2;Q9NUY8;E9PGE5 Q9NUY8-2 TBC1D23 TBC1 domain family member 23 1 VISFIENT(0.015)S(0.314)T(0.671)PVDR 111.66 0.00092478 3310800.0 14711.0 11402.0 14729.0 19792.0 15891.0 16277.0 17476.0 20715.0 12900.0 11652.0 True False 19388.79199219124 15087.473521737453 14533.683836242362 15229.260183351797 13684.808948626558 15259.196616883371 19031.330144502048 17513.972733344515 13581.867664128045 11244.06702659277 1.7243575608661703 1.3418163984663947 1.292564674496291 1.3544263074325198 1.2170693145337284 1.357088727841503 1.6925664085327863 1.5576190262760896 1.207914149925135 1.0 13.456876338402113 -4.759643323954441 24.785711863428006 1.3604540267138214 1.724358064490309 0.28457428738558066 0.18108875316030779 60.255246453857396 831262.8465490506 0.045757335407098594 0.28608553989495 1.7392286307361288e-05 4.759643323954441 0.3639040377764875 VISFIENTST(ph)PVDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VISFIENTSTPVDR 14 0 Q9NUY8-2;Q9NUY8;E9PGE5 Q9NUY8-2 TBC1D23 TBC1 domain family member 23 1 VISFIENT(0.022)S(0.222)T(0.756)PVDR 133.04 2.7836999999999998e-05 2632600.0 14759.0 13430.0 13103.0 8079.9 12540.0 11783.0 11394.0 8669.1 9732.5 9872.1 True False 17257.40719646255 14763.241644222066 13415.425213404216 7627.20939838924 10082.877019143209 11165.078737213991 10314.677834583586 8441.545310670706 9874.819400418952 11661.833582499397 1.4798193675444213 1.2659451483150015 1.150370147069873 0.6540317476177322 0.8646047765828448 0.9574033669944602 0.8844816521874012 0.7238608963978622 0.8467638755570848 1.0 13.509507019923932 -5.429633668624214 2.430049762814185 0.8437792822350323 1.3965865506655797 0.7849342890502851 0.1110586668387411 0.12766266703566742 1.4501594054297084 0.030927188360125837 0.08098490674635578 3.7184875468029127e-06 5.429633668624214 0.5528072684305474 VISFIENTST(ph)PVDR ddPTM_PC-9_Lapatinib_30min_R1 2 VISFIENTSTPVDR 14 0 Q9NUY8-2;Q9NUY8;E9PGE5 Q9NUY8-2 TBC1D23 TBC1 domain family member 23 1 VISFIENT(0.064)S(0.215)T(0.721)PVDR;VISFIENT(0.032)S(0.159)T(0.81)PVDR 141.59 0.00033385 3528300.0 34401.0 40438.0 40701.0 32290.5 35134.2 28982.1 33111.0 29492.4 36291.0 28746.6 True False 33910.43543162925 40344.368295503315 37354.720890403434 34665.25108795029 33067.67543249491 27742.603143574892 34825.32556663274 30862.724571299543 32203.525418828045 33715.411507563236 1.005784414763031 1.1966150342389572 1.1079420128692128 1.0281722671596039 0.9807881308248892 0.8228463454272688 1.0329200804451257 0.9153892297703748 0.955157418488099 1.0 15.041120585885105 -6.04827871382456 2.3116450827701347 0.9437379174009503 1.1125407802396095 0.5026633695884671 0.06798494774479606 0.22676846821680868 2.408136693091764 0.020870979325383756 0.031022026015768207 8.947903385429387e-07 6.04827871382456 0.1688028628386592 VISGTTLGYLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 VISGTTLGYLSPK 13 0 H0YBY0;E7EPX0;E7EVJ4;Q9NUL3-4;Q9NUL3-6;Q9NUL3-8;Q9NUL3-3;Q9NUL3-7;Q9NUL3-2;Q9NUL3;E5RJ67;E5RJN7 H0YBY0 STAU2 Double-stranded RNA-binding protein Staufen homolog 2 1 VISGTTLGYLS(1)PK 98.337 0.0027844000000000002 14869000.0 42050.0 44464.0 39819.0 51187.0 51106.0 44209.0 41388.0 46886.0 40917.0 36043.0 True False 55421.02530566526 58836.11845908916 39290.974042727605 39386.627981266596 44010.8140537731 41444.60424130963 45071.45182082002 39640.84603309636 43079.789086288896 34781.145540635385 1.5934215059396466 1.6916095644506577 1.1296630238018845 1.1324131902225747 1.2653641324824838 1.1915824966975057 1.2958587510627646 1.1397222666741469 1.2385960386485277 1.0 15.086017829116827 -5.260897643581187 24.99997738976198 1.1858764408889186 1.6425155714702129 0.8357855147602317 0.08291279672111294 16.05332444880048 740780.1944211813 0.02038450787289595 0.04768698592487852 5.484062004574977e-06 5.260897643581187 0.45663913058129424 VISGTTLGYLS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VISGTTLGYLSPK 13 0 H0YBY0;E7EPX0;E7EVJ4;Q9NUL3-4;Q9NUL3-6;Q9NUL3-8;Q9NUL3-3;Q9NUL3-7;Q9NUL3-2;Q9NUL3;E5RJ67;E5RJN7 H0YBY0 STAU2 Double-stranded RNA-binding protein Staufen homolog 2 1 VISGTTLGYLS(0.999)PK 84.29700000000001 0.008657399999999999 8710400.0 32021.0 37893.0 30868.0 33330.0 42722.0 47467.0 54451.0 48008.0 47624.0 37178.0 True False 37441.522856421674 41654.76661388733 31604.01018754191 31462.628157317933 34350.930782443065 44977.746959122174 49293.007088898594 46747.840868680636 48320.41090424374 43918.077099113914 0.8525310152337496 0.9484651734610611 0.7196127944358371 0.7163935726583238 0.7821592622309078 1.0241283300636503 1.1223853671383333 1.0644327793127313 1.1002396756851325 1.0 15.42252726858511 -6.831122293699047 4.578824375157765 1.0759094362087411 0.801990799324006 0.7783063986185788 0.06917132725090457 0.10428538475499771 4.185513802429676 0.02708930199740227 0.024171034875092753 1.4752910451423852e-07 6.831122293699047 -0.27391863688473517 VISGTTLGYLS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 VISGTTLGYLSPK 13 0 H0YBY0;E7EPX0;E7EVJ4;Q9NUL3-4;Q9NUL3-6;Q9NUL3-8;Q9NUL3-3;Q9NUL3-7;Q9NUL3-2;Q9NUL3;E5RJ67;E5RJN7 H0YBY0 STAU2 Double-stranded RNA-binding protein Staufen homolog 2 1 VISGTT(0.001)LGYLS(0.999)PK;VISGTTLGYLS(1)PK 123.72 0.00016248 14959800.0 76726.0 73022.0 87244.0 73576.0 96681.0 107608.0 119300.0 132892.0 122057.0 117494.0 True False 75631.87317017493 72852.92204545834 80071.13509157895 78987.02448234073 90994.41366215942 103005.85668649989 125476.77026061688 139066.647466098 108309.65534280923 137802.6813490857 0.5488418108395301 0.5286756493576873 0.5810564374196788 0.5731893146712329 0.6603239702691254 0.7474880436147864 0.9105539096351509 1.0091722897162674 0.7859763996060143 1.0 17.072244434550086 -6.891153661675358 1.3564015656947785 0.9369081389601277 0.5533527984290362 0.8850326831836788 0.059857741267209344 0.12814681303334002 0.4883816197519785 0.029196049389922585 0.023494948225037237 1.2848319814378546e-07 6.891153661675358 -0.3835553405310915 VISRPPPS(ph)VSPPK ddPTM_PC-9_Lapatinib_30min_R1 1 VISRPPPSVSPPK 13 1 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;A0A0C4DGG3 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 VISRPPPS(0.673)VS(0.327)PPK 62.861000000000004 0.022533 30904000.0 168120.0 180320.0 131260.0 145550.0 113960.0 121340.0 159020.0 131160.0 132490.0 125510.0 True False 165722.57797056795 179902.48011882819 120468.30947825238 156254.23254056668 107257.09685398034 116150.57105735531 167253.27750916418 137254.1724231208 117567.58101844887 147204.23626843767 1.1258003313733493 1.2221284161330987 0.8183752895437711 1.0614791836263848 0.7286277866242191 0.7890436715798468 1.1361988061550459 0.9324064028485416 0.7986698209150435 1.0 17.167459664551338 -5.255847968884851 24.86513270610761 0.9086485249851992 1.1739643974218634 0.4208304959229916 0.1247568840035129 404.0259203108681 1796697.4754633568 0.03226809278943536 0.08046832539637898 5.548199017621775e-06 5.255847968884851 0.2653158724366642 VISRPPPSVS(ph)PPK ddPTM_PC-9_AZD4547_30min_R2 2 VISRPPPSVSPPK 13 1 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;A0A0C4DGG3 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 VIS(0.005)RPPPS(0.319)VS(0.676)PPK;VISRPPPS(0.059)VS(0.94)PPK 100.54 0.012473999999999999 34719000.0 56839.0 62790.0 54688.0 61732.0 58671.0 66304.0 60079.0 58338.0 49062.0 63589.0 True False 74912.61967535577 83085.63957462682 53962.801387495616 47500.64114989254 50525.54438517829 62158.0003984663 65425.9146115552 49323.202573876544 51655.317157941834 61362.76846498525 1.2208155132065517 1.3540073509238268 0.8794062383004737 0.7740954708879749 0.8233908874891965 1.0129595185056688 1.0662151700161386 0.803796891954464 0.8418022597435011 1.0 15.905075953012936 -5.265955005979681 24.74706871942402 0.8959091757054399 1.2874114494522413 0.7179258069336103 0.09705252455262299 161.6013478242979 885632.8477590004 0.027179450124102455 0.059820772668629715 5.420570459905228e-06 5.265955005979681 0.39150227374680135 VISRPPPSVS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VISRPPPSVSPPK 13 1 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;A0A0C4DGG3 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 VIS(0.002)RPPPS(0.012)VS(0.986)PPK;VISRPPPS(0.022)VS(0.978)PPK 59.345 0.02915 57830000.0 79291.0 85528.0 78924.0 91351.0 84706.0 74775.0 96523.0 74722.0 72912.0 63184.0 True False 92713.40023136497 94018.65460513937 80805.8474809368 86232.89963393795 68108.46736710893 70853.66736613557 87379.642673996 72760.6266745034 73978.20006404776 74638.75903573124 1.2421615984663008 1.2596492200537597 1.0826258170001626 1.1553367278340778 0.9125080353292567 0.9492878536768857 1.1707006360082355 0.9748370366081683 0.9911499202262024 1.0 16.187637379299147 -5.5345399496551115 1.3223978213322478 1.0092957006963066 1.266891290838649 0.598780915840248 0.07563742780275153 0.3717906744060191 1.1886798632742577 0.02528579146340308 0.08891217094011858 2.9205190966575395e-06 5.5345399496551115 0.25759559014234235 VISRPPPSVS(ph)PPK ddPTM_PC-9_Lapatinib_30min_R1 1 VISRPPPSVSPPK 13 1 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;A0A0C4DGG3 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 VISRPPPSVS(1)PPK 85.57600000000001 0.0037854 30392000.0 149780.0 134380.0 110950.0 133690.0 119700.0 128890.0 128480.0 145340.0 112030.0 88368.0 True False 147644.10973371196 134068.85136628235 101828.11927938547 143522.008576766 112659.48133925456 123377.67515726476 135132.06574253197 152093.0269897555 99412.00167180023 103642.29105704153 1.4245546699894271 1.293572826294384 0.9824958348647698 1.3847822844612332 1.0870030003220428 1.1904182539670172 1.303831325652184 1.4674803638415153 0.9591837526737702 1.0 16.661253286809057 -8.291762289163186 24.760588024234345 0.9795916605661933 1.2548173167110799 0.39288909612717426 0.14217330304251283 755.3141847803067 616754.6810546268 0.13692752447616677 0.0353724769819663 5.107845010812002e-09 8.291762289163186 0.2752256561448866 VIVGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 VIVGSPR 7 0 A0A1C7CYW6;A0A1B0GWB1;A0A1B0GTQ2;P0DI83 A0A1C7CYW6 RAB34 Ras-related protein Rab-34, isoform NARR 1 VIVGS(1)PR;VIVGS(1)PR 104.06 0.010406 10395900.0 55238.0 59874.0 73111.0 101005.0 76043.0 74832.0 61193.0 90559.0 63402.0 77095.0 True False 72802.53497822452 79227.09960011471 72141.50037012115 77719.85776169396 65485.74204772565 70152.74321033474 66639.05845345132 76565.18738879765 66753.30028225166 74395.92751589174 0.9785822612759703 1.0649386632513047 0.9696969011470551 1.0446789274196788 0.8802328868571094 0.9429648309089148 0.8957353000164763 1.0291583147806382 0.8972708925228798 1.0 16.18293602892799 -6.2465475341561625 24.982344909609413 0.9401972534971027 1.0148804165642302 0.3360428429858875 0.0506618703712991 913.9527557414123 1533234.092815117 0.014182707228537225 0.018231706414473324 5.66829527820158e-07 6.2465475341561625 0.07468316306712752 VIVGS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VIVGSPR 7 0 A0A1C7CYW6;A0A1B0GWB1;A0A1B0GTQ2;P0DI83 A0A1C7CYW6 RAB34 Ras-related protein Rab-34, isoform NARR 1 VIVGS(1)PR 85.161 0.019469999999999998 2853300.0 23260.0 21169.0 28595.0 24436.0 29405.0 27226.0 24778.0 22769.0 21552.0 20628.0 True False 27197.458594059164 23270.51841895287 29276.813247141406 23066.93014258091 23643.301335558688 25798.220631366214 22430.848462814818 22171.33787574965 21867.15722762179 24367.693108841857 1.116127754587919 0.9549742076532113 1.2014601922460304 0.9466193635790265 0.9702724517233713 1.0587059068798468 0.9205158798834243 0.9098660992125162 0.8973831511234543 1.0 14.572682057038016 -6.534604285222049 0.7867483443430365 0.9276595947722768 1.072877607771573 0.31731573277585423 0.07759374961391405 0.7933780370499777 1.0908946633468788 0.047541625153427 0.05899499867340784 2.9200864885004574e-07 6.534604285222049 0.14521801299929615 VIVGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 VIVGSPR 7 0 A0A1C7CYW6;A0A1B0GWB1;A0A1B0GTQ2;P0DI83 A0A1C7CYW6 RAB34 Ras-related protein Rab-34, isoform NARR 1 VIVGS(1)PR;VIVGS(1)PR 87.696 0.017768 13242200.0 89593.0 83739.0 97042.0 75769.0 75442.0 73485.0 68326.0 66740.0 84166.0 71633.0 True False 88315.38739065593 83545.10749040879 89063.58135295262 81341.30501797462 71004.64988467871 70342.21785190176 71863.58595831442 69840.98404634855 74686.3387727283 84014.66860502708 1.0511900940280745 0.9944109627233572 1.0600956098709582 0.9681797996535513 0.845145866354463 0.837261147605036 0.8553695104858678 0.8312951203162819 0.8889678435065491 1.0 16.35835361787175 -6.076327947731601 3.5836949214162197 0.865314756674677 1.0302618314505105 0.6782412208367266 0.049063035371647294 0.12483730304493257 3.0757110250030593 0.013979764291301638 0.01918927638220753 8.388263264268931e-07 6.076327947731601 0.16494707477583348 VIVMPT(ph)T(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VIVMPTTK 8 0 Q9NSE4 Q9NSE4 IARS2 Isoleucine--tRNA ligase, mitochondrial 2 VIVMPT(1)T(1)K 66.568 0.024468 0.0 0.0 455.81 0.0 850.27 534.19 479.05 443.5 633.86 578.87 686.79 True False 0.0 501.0598044566534 0.0 802.6321285125337 429.5193042150008 453.9277746806724 401.4884693380568 617.2218466301848 587.3348786355525 811.2995903733512 0.0 0.6176014513036685 0.0 0.9893165706433688 0.529421325132607 0.5595069689013152 0.4948707901520032 0.7607816569291574 0.7239432702847384 1.0 9.66409094975753 -6.257389405535642 0.22046569320765824 1.0087213281433205 3.683772287265517e-20 0.4135381391501076 0.2516968954728817 6.678228068351555 0.5658013990395251 0.5587405409503523 1.9520709720024019 5.528541760858703e-07 6.257389405535642 -1.0087213281433205 VIVVGNPANTNCLTASK ddPTM_PC-9_Lapatinib_30min_R1 2 VIVVGNPANTNCLTASK 17 0 A0A5K1VW95;P40925;P40925-3;B9A041;P40925-2;C9JRL4;C9JF79 A0A5K1VW95 MDH1 Malate dehydrogenase, cytoplasmic;Malate dehydrogenase 0 ; 228.25 1.6561e-28 7816100.0 71655.0 71595.0 72221.0 67752.0 70209.0 71793.0 76062.0 64239.0 68115.0 68841.0 False True 70633.18656008223 71429.22617628379 66283.26816112205 72734.70809404651 66079.44465620487 68722.58074765714 80000.11818577576 67223.77845599913 60443.17141725144 80740.07512513346 0.8748219078396043 0.8846811953739276 0.8209463275627895 0.9008501414114368 0.8184218871953353 0.8511582462754557 0.9908353201528375 0.8325949455931722 0.7486142578338545 1.0 16.300997308733578 VIY(ph)DFIEK ddPTM_PC-9_AZD4547_30min_R2 2 VIYDFIEK 8 0 O00401 O00401 WASL Neural Wiskott-Aldrich syndrome protein 1 VIY(1)DFIEK;VIY(1)DFIEK 107.47 0.0055236999999999994 3888000.0 8792.5 7486.2 8454.3 17353.300000000003 15160.8 11651.099999999999 10857.2 14199.2 13349.0 13041.5 True False 11588.33210463881 9905.967749380014 8342.19045805851 13352.764790812378 13055.984614457075 10922.554875159425 11823.469766816637 12005.039905155949 14054.60088747638 12584.921054523651 0.9208108699635731 0.7871299078049689 0.6628718942229606 1.061012995867203 1.037430791809703 0.8679080963510146 0.9394949492008684 0.9539225437445821 1.1167810132924474 1.0 13.619408546020177 -5.771266327261992 24.999521955275256 0.9886836535319108 0.7899567781988422 0.5405687149644001 0.08697174688752997 159.14325584075394 404856.9415395527 0.0254044463811609 0.03820208883778461 1.693299081254881e-06 5.771266327261992 -0.19872687533306854 VIY(ph)DFIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VIYDFIEK 8 0 O00401 O00401 WASL Neural Wiskott-Aldrich syndrome protein 1 VIY(1)DFIEK 101.64 0.0091719 0.0 3638.4 5818.1 5733.7 6374.2 6542.2 5222.2 5877.9 4658.9 3719.2 4086.8 True False 4254.309258324366 6395.682517516631 5870.413153178338 6017.0742394352255 5260.302873575653 4948.3386388423105 5321.102759689212 4536.608811512582 3773.5862639648763 4827.7044889089975 0.8812281837254269 1.3247874910756972 1.215984359992378 1.246363412105825 1.089607469898063 1.0249878902510403 1.1022014234536788 0.9397030870333575 0.7816522889158157 1.0 12.23712165391296 -7.394192111506271 1.056141913060905 0.8900420358106802 1.1711801905393462 0.38207682675010146 0.12688869497851765 0.5191173869697292 1.0961105761809429 0.09534723512748973 0.04867786308851173 4.034668786666337e-08 7.394192111506271 0.281138154728666 VIY(ph)DFIEK ddPTM_PC-9_Lapatinib_30min_R1 1 VIYDFIEK 8 0 O00401 O00401 WASL Neural Wiskott-Aldrich syndrome protein 1 VIY(1)DFIEK 78.149 0.038306 0.0 3187.6 2508.2 3499.1 3764.9 2954.1 2749.1 2819.8 2957.3 3516.8 2762.4 True False 3142.1442394657506 2502.3924170033483 3211.417504916604 4041.7833053382283 2780.3456459840604 2631.5274014650995 2965.7954466126353 3094.706954154431 3120.7009504542284 3239.8771593333713 0.9698343748663205 0.7723726221515862 0.9912158230028008 1.247511281004819 0.8581639084600778 0.8122306100045336 0.9154036714227985 0.9551926823025568 0.9632158248544015 1.0 11.661723398704018 -8.520183926527778 2.034719117544162 0.9989947411257297 0.9384138780145784 0.02251754557506669 0.12247124484316115 1.9053397673837587 18.03165901061026 0.1252490262336049 0.03497249246913569 3.0186730220635407e-09 8.520183926527778 -0.060580863111151295 VIYINS(ph)PLPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VIYINSPLPQK 11 0 Q659A1;H0YK97;H0YNU9 Q659A1 ICE2 Little elongation complex subunit 2 1 VIYINS(1)PLPQK 84.507 0.034964 0.0 11342.0 19751.0 13286.0 16178.0 17505.0 16574.0 18435.0 14641.0 18749.0 13162.0 True False 13261.976585288867 21711.74875018839 13602.78862743559 15271.599109783674 14075.02091069393 15704.830263140511 16688.703342158005 14256.689263421787 19023.168655376823 15548.166409665331 0.8529608081017654 1.3964185987031592 0.8748805659154496 0.9822122240915988 0.9052527828583287 1.0100760340060286 1.0733550762476836 0.916937012878849 1.2234991673070401 1.0 13.924456833367893 -10.63657866667182 14.893497489936465 1.0000133529022128 1.0254679148538473 0.0023500330574592887 0.16121036510253922 0.0 0.0 0.14777650478092294 0.0358410669527258 2.308986178887188e-11 10.63657866667182 0.025454561951634425 VIYSQPS(ph)AR ddPTM_PC-9_AZD4547_30min_R2 4 VIYSQPSAR 9 0 A0A087WY82;Q9Y624-2;Q9Y624 A0A087WY82 F11R Junctional adhesion molecule A 1 VIYSQPS(1)AR;VIYS(0.001)QPS(0.999)AR;VIYSQPS(1)AR;VIYSQPS(1)AR 89.561 0.0092508 49033000.0 40041.0 89577.0 64534.0 55429.6 104102.0 62358.0 75455.0 102375.0 74412.0 61632.0 True False 52773.20509546117 118531.01347629138 63678.23699423349 42651.16209878316 89649.23423132094 58458.744402261706 82170.34882429607 86555.29609346604 78345.26640489123 59474.28243932077 0.8873281514460231 1.9929792948275387 1.070685250540044 0.717136220051052 1.507361342657416 0.9829247534327938 1.3816114369791883 1.4553398972366745 1.3172965387993334 1.0 15.859978340105224 VIYSQPS(ph)AR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VIYSQPSAR 9 0 A0A087WY82;Q9Y624-2;Q9Y624 A0A087WY82 F11R Junctional adhesion molecule A 1 VIYSQPS(1)AR;VIYSQPS(1)AR;VIYSQPS(1)AR;VIYS(0.005)QPS(0.995)AR 108.31 0.0024439 47470000.0 178412.0 155196.0 125938.0 98875.0 205810.0 102516.0 66697.8 110331.0 73903.6 68914.9 True False 208613.62780237678 170602.83322536733 128940.83954252447 93335.35430707518 165483.0079194467 97139.88049089628 60379.701533744876 107434.92815535734 74984.30033812499 81408.62583995156 2.562549430726282 2.0956358305417235 1.583871957205379 1.1465044808712461 2.0327453781714047 1.1932381794758724 0.7416867796350068 1.319699565578876 0.9210854447481188 1.0 16.31289404624254 -1.5228787453081676 0.3418839439374857 0.9853009535282937 18.860547488422952 0.7249362270289899 0.29529567762883596 32.86987266043724 0.4652571531353522 0.2661327849247555 375.74929552399306 0.02999999999807757 1.5228787453081676 17.875246534894657 up VIYSQPS(ph)AR ddPTM_PC-9_Lapatinib_30min_R1 3 VIYSQPSAR 9 0 A0A087WY82;Q9Y624-2;Q9Y624 A0A087WY82 F11R Junctional adhesion molecule A 1 VIYSQPS(1)AR;VIYSQPS(1)AR;VIYSQPS(1)AR 99.34299999999999 0.004171500000000001 34920300.0 194516.0 206199.0 86627.0 66882.0 61036.0 33220.6 25027.5 39106.0 93657.0 35983.9 True False 191742.16617013482 205721.55888432835 79504.86244989012 71800.72539181136 57445.98248139304 31799.83237900095 26323.30148950201 40923.00752347181 83108.36240806754 42203.66916946717 4.543258203456237 4.874494633588884 1.883837685549128 1.7012910679282025 1.3611608566715128 0.7534850169379818 0.6237206860806778 0.9696552060236063 1.9692212559611626 1.0 15.365080811242118 -5.3519196703977645 2.7195435529888163 1.167369161834775 4.821027990490631 0.9169276940202319 0.41510056196179634 0.07327721983321189 1.03652657029053 0.12285701461565118 0.3336157441712614 4.447135166289876e-06 5.3519196703977645 3.653658828655856 VKAPVHFVEPLS(ph)PTGVAGHR ddPTM_PC-9_AZD4547_30min_R2 1 VKAPVHFVEPLSPTGVAGHR 20 1 Q5T5Y3-2;Q5T5Y3;Q5T5Y3-3 Q5T5Y3-2 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1 1 VKAPVHFVEPLS(0.958)PT(0.042)GVAGHR 70.767 0.0017041 6586800.0 18054.0 12991.0 19704.0 26017.0 20997.0 19423.0 17970.0 21782.0 17476.0 20859.0 True False 23794.796453471605 17190.086697148865 19442.712085635114 20019.182608643056 18081.9289846021 18208.47673955432 19569.295187497224 18416.092400565303 18399.745682038894 20128.73275898547 1.1821308742275196 0.8540073984277629 0.9659183376537147 0.9945575237321629 0.8983143251544399 0.9046012462670336 0.9722070148087931 0.9149156393039377 0.9141035306271452 1.0 14.29696872717501 -4.74970526344544 24.999989145426646 0.9345746629818353 1.1821314257581361 0.7346461037403431 0.04448247588289538 268.88695996931483 572838.4939459137 0.010737834860880402 0.1713887252332692 1.7794866596319436e-05 4.74970526344544 0.2475567627763008 VKAQT(ph)PPGPS(ph)LSGSKSPCPQEK ddPTM_PC-9_AZD4547_30min_R2 1 VKAQTPPGPSLSGSKSPCPQEK 22 2 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 VKAQT(1)PPGPS(0.617)LS(0.205)GS(0.164)KS(0.014)PCPQEK 58.47 0.011072 127830000.0 41632.0 32490.0 43240.0 62864.0 56282.0 43619.0 42618.0 44565.0 40004.0 47415.0 True False 54870.11000060539 42991.75712342133 42666.60934748592 48371.67603911817 48468.21579803659 40891.4970345786 46410.91943799428 37678.50325182226 42118.529770215384 45755.015282002794 1.199215204331664 0.9396075350089904 0.9325012588132243 1.0571885014350462 1.0592984288019898 0.8937052426395494 1.0143351313937705 0.8234835682951386 0.9205226904772168 1.0 15.481642267774783 -6.761780126670168 24.999999943614643 0.9246224072510164 1.0273738975974334 0.27715483015829223 0.08548285492835653 13.316881299776844 976993.7448108409 0.029188091109227685 0.027345834298412242 1.730692347268901e-07 6.761780126670168 0.10275149034641695 VKAQT(ph)PPGPSLS(ph)GSKSPCPQEK ddPTM_PC-9_AZD4547_30min_R2 1 VKAQTPPGPSLSGSKSPCPQEK 22 2 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 VKAQT(0.903)PPGPS(0.105)LS(0.459)GS(0.312)KS(0.22)PCPQEK 65.775 0.018503 25685000.0 50956.0 42716.0 48178.0 70103.0 69022.0 63305.0 56930.0 50073.0 51285.0 58693.0 True False 67158.94804935729 56523.111643092176 47539.12824105404 53941.83643055335 59439.48670644398 59346.52834255711 61996.65971197649 42335.36841307074 53995.82039959739 56638.17593475884 1.1857540773685449 0.9979684322496685 0.8393477977789056 0.9523936027298727 1.0494597632330525 1.047818496325129 1.094609045732512 0.7474705481658976 0.9533467402233229 1.0 15.789487182889625 -7.743387266699943 24.993242656294267 0.8878063624730822 1.0149631308296805 0.22119857208886973 0.10459645934800475 352.5272974528889 488077.09663807164 0.05093263567329351 0.029330832033198903 1.8055633608620547e-08 7.743387266699943 0.12715676835659828 VKAQT(ph)PPGPSLSGSK ddPTM_PC-9_AZD4547_30min_R2 2 VKAQTPPGPSLSGSK 15 1 Q9UQ35;Q9UQ35-2;I3L4D8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 VKAQT(0.999)PPGPS(0.001)LSGSK;VKAQT(1)PPGPSLSGSK 66.60600000000001 0.022725 370080000.0 856380.0 585830.0 783460.0 942710.0 894640.0 861760.0 665400.0 725430.0 669550.0 736480.0 True False 1128691.0261894336 775188.0909699571 773070.8084963307 725382.7742243117 770434.6786104875 807874.0109704144 724619.3109493959 613331.4622230314 704941.0460865843 710696.0593670659 1.5881487047988236 1.0907448841918819 1.087765716873138 1.0206652543850117 1.0840564942721418 1.1367363028435722 1.019591007152523 0.8630010735802507 0.9919022862099349 1.0 19.438873174373015 VKAQT(ph)PPGPSLSGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VKAQTPPGPSLSGSK 15 1 Q9UQ35;Q9UQ35-2;I3L4D8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 VKAQT(0.996)PPGPS(0.003)LSGS(0.001)K 58.723 0.041516000000000004 143720000.0 131890.0 100310.0 96996.0 107710.0 118520.0 119530.0 120290.0 91444.0 109390.0 100130.0 True False 154216.37205375996 110268.11387430478 99308.75249937868 101675.35790053145 95296.8568029389 113261.63637946108 108895.26037581726 89043.69189292662 110989.62180445173 118282.77637135629 1.3037939823934117 0.9322415085025654 0.839587601390016 0.8595956319229032 0.8056697663550639 0.9575496945038641 0.9206349708425314 0.7528035325563234 0.9383413647308444 1.0 16.851880486806962 -4.763046632270321 3.7442068656049665 0.8759192429409651 1.3576223723576681 0.7582412948173465 0.07048857034301341 0.12438511378147145 3.0140700638874467 0.01706129089591791 0.17158490988075173 1.7256525904911744e-05 4.763046632270321 0.481703129416703 VKAQT(ph)PPGPSLSGSK ddPTM_PC-9_Lapatinib_30min_R1 3 VKAQTPPGPSLSGSK 15 1 Q9UQ35;Q9UQ35-2;I3L4D8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 VKAQT(1)PPGPSLSGSK;VKAQT(0.991)PPGPS(0.007)LS(0.002)GSK;VKAQT(0.94)PPGPS(0.04)LS(0.019)GSK 135.61 0.00024558 174966400.0 1011930.0 596213.0 687169.0 580194.0 777402.0 769668.0 649804.0 627899.0 701967.0 645738.0 True False 997499.6926347673 594832.5054297176 630672.6173690493 622863.4022304451 731676.7427911379 736751.0938237385 683447.6716046088 657073.4797979946 622904.0844197856 757352.9529081994 1.3170869523970505 0.7854098979156139 0.8327327634325534 0.8224215669044125 0.9660974318269097 0.972797545707915 0.9024163291107563 0.8675921540608822 0.8224752831924185 1.0 19.53060627760503 -4.753415304913836 24.999849666706147 0.8837464562055641 1.317087742437414 0.7749077428582724 0.06973064203411539 142.82596444090433 444954.1417571963 0.018154284348939464 0.1955868660162656 1.7643498102689876e-05 4.753415304913836 0.43334128623185 VKEDPDGEHAR ddPTM_PC-9_AZD4547_30min_R2 3 VKEDPDGEHAR 11 1 A0A087X0X3;P52272-2;P52272;M0R2T0;M0R019;M0QYQ7;M0R0N3 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 ;; 93.561 0.0031697 45417900.0 214742.0 211736.0 254475.0 320291.0 291118.0 271334.0 240176.0 287429.0 245663.0 256564.0 False True 283025.48908892233 280175.521276846 251100.4952289887 246452.85839662104 250701.29076246047 254367.44208671356 261551.19871743614 243013.45251134384 258648.2446490454 247581.77245200344 1.1431596368581216 1.1316484186296922 1.0142123660483422 0.9954402376063397 1.0125999514405357 1.027407791645993 1.056423484358651 0.981548238000658 1.0446982509553984 1.0 17.917545578322212 -5.249132444594729 6.332858298190665 1.0166660970502492 1.138601792892717 0.8381226905445989 0.021253506157403235 0.053413109370214165 10.163692155754934 0.0054042466028780345 0.013435428639772188 5.634657923042323e-06 5.249132444594729 0.12193569584246777 VKEDPDGEHAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VKEDPDGEHAR 11 1 A0A087X0X3;P52272-2;P52272;M0R2T0;M0R019;M0QYQ7;M0R0N3 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 ;;; 102.95 0.0013991 43288200.0 359776.0 341216.0 352109.0 389626.0 406480.0 324767.0 380635.0 320844.0 315153.0 275183.0 False True 420678.9709000959 375089.6694620169 360504.613940819 367796.51840453455 326833.1619410954 307735.6468003717 344578.4972412427 312422.18496231874 319761.51641410054 325071.4995525699 1.294112130651628 1.1538682104653661 1.1090009872813196 1.131432681458607 1.0054193074168307 0.9466706469928636 1.0600083295998644 0.9610875927060302 0.9836651839802073 1.0 18.310397548593066 -3.5792698745873355 0.43025330713736704 0.9769088758608686 2.0438936888171115 0.8508366232756892 0.039754411047820314 5.197078345889632 0.33584895820281013 0.02830260672261015 3.5236508552774004 0.0002634693654146764 3.5792698745873355 1.066984812956243 VKEDPDGEHAR ddPTM_PC-9_Lapatinib_30min_R1 4 VKEDPDGEHAR 11 1 A0A087X0X3;P52272-2;P52272;M0R2T0;M0R019;M0QYQ7;M0R0N3 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 ;;; 104.07 0.0012294 44178930.0 321493.0 327183.0 357612.0 303790.0 360513.0 338538.0 326575.9 323854.0 339775.0 293628.0 False True 316908.45086540503 326425.42786556354 328210.52178224054 326131.7300137326 339308.3341358289 324059.51891062217 343484.4021538492 338901.4391271532 301505.9615106303 344381.2085652829 0.9202257352707153 0.9478607419535913 0.9530442243047736 0.9470079142018841 0.9852695957175248 0.9409907127647226 0.9973958903995666 0.984088070713966 0.8755006196961966 1.0 18.39364689751619 -3.219723824677505 0.7660672801083616 0.9627094231471268 0.5029585681607551 0.11671660893682467 0.034440580402743365 54.48845639027082 3.552163522300019 0.012365625341918722 36.0924265101078 0.0006029428859280597 3.219723824677505 -0.4597508549863717 VKEEASS(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 2 VKEEASSPLK 10 1 D6RA28;A0A590UJ84;B1AKN3;Q9P2R6-2;Q9P2R6 D6RA28 RERE Arginine-glutamic acid dipeptide repeats protein 1 VKEEAS(0.076)S(0.924)PLK;VKEEAS(0.023)S(0.977)PLK 95.094 0.029197000000000004 38610500.0 101902.0 146682.0 136458.0 147404.0 162945.0 142672.0 138586.0 141737.0 144914.0 124785.0 True False 100448.85879346172 146342.36684111494 125238.9499831125 158244.5818853294 153360.8954621958 136570.2511446761 145761.30497349417 148322.61845635757 128592.25930792888 146353.92098443882 0.686342109031312 0.9999210534077518 0.85572664634266 1.081245933289036 1.0478769166594586 0.9331506134311018 0.9959508019535216 1.0134516209656457 0.8786389762772501 1.0 17.159101872107144 -4.759020252198848 24.999245524987035 0.9795403328788791 0.6863417259003368 0.630838163818526 0.06702991768555634 41.91751931789771 433082.06979276123 0.016483117407092733 0.10809758858143724 1.7417256506311403e-05 4.759020252198848 -0.2931986069785423 VKEEPPS(ph)PPQSPR ddPTM_PC-9_AZD4547_30min_R2 2 VKEEPPSPPQSPR 13 1 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 1 VKEEPPS(0.961)PPQS(0.039)PR;VKEEPPS(0.853)PPQS(0.147)PR 70.117 0.013658000000000002 46073000.0 227270.0 181591.0 310370.0 446160.0 392970.0 361380.0 290830.0 381050.0 272730.0 390870.0 True False 299537.1324903333 240286.7395444507 306254.2910078446 343304.7051032862 338412.89865595434 338782.8514719734 316713.3065876354 322167.4781579016 287145.95101067005 377185.76027156867 0.7941369055784889 0.6370514607217608 0.811945527284343 0.9101740873147264 0.8972048637581165 0.898185687678279 0.8396746111507659 0.8541347847435846 0.7612852372897875 1.0 18.524915686045333 -5.49173746420907 5.9545613436310205 0.8731691830918059 0.7162084813375713 0.4861626147731243 0.06711232250569765 0.1489613150028672 16.189616499469686 0.017184678153713308 0.034692502060493194 3.2230165514568344e-06 5.49173746420907 -0.1569607017542346 VKEEPPS(ph)PPQSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VKEEPPSPPQSPR 13 1 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 1 VKEEPPS(0.978)PPQS(0.022)PR;VKEEPPS(0.969)PPQS(0.031)PR 73.219 0.01028 41220000.0 165705.0 158373.0 190836.0 179256.0 193522.0 177124.0 153171.0 129861.0 144233.0 130228.0 True False 193755.5836770671 174095.22478930646 195386.25398956012 169212.86747579314 155602.75330930058 167835.30563101845 138661.53401799191 126452.2863491029 146342.1347629724 153837.30551571888 1.2594837320344865 1.1316840489741784 1.2700836987137416 1.0999469011013276 1.0114760706947075 1.0909922340902498 0.9013518115982841 0.8219871371588875 0.9512785879366521 1.0 17.23104587342101 -6.48245549277223 0.9059706605450737 0.9076110192439862 1.2217087990329305 0.7348069734819371 0.07113978817144995 0.29037547237141886 0.5204929791816874 0.0388332059977297 0.048709300343867425 3.292641951520354e-07 6.48245549277223 0.31409777978894426 VKEEPPS(ph)PPQSPR ddPTM_PC-9_Lapatinib_30min_R1 1 VKEEPPSPPQSPR 13 1 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 1 VKEEPPS(0.995)PPQS(0.005)PR 54.412 0.038432999999999995 14032000.0 135150.0 101360.0 112580.0 90861.0 100280.0 92118.0 70214.0 68013.0 80238.0 66208.0 True False 133222.73621652572 101125.30714753967 103324.10697136735 97543.22104341039 94381.72755806564 88178.32787754618 73849.33736025947 71173.13227366342 71200.75149640192 77651.96458338544 1.7156389658817506 1.3022891009917426 1.330605188493515 1.256159088398401 1.2154454567175204 1.135558235398631 0.9510298645561944 0.9165657643759312 0.9169214440150322 1.0 16.244734804598004 -2.7366904721979988 0.27985383633962296 0.8913932451024673 3.8918557311191173 0.8752952492867392 0.08331718672541726 9.128213871613545 0.2346303830478299 0.10023391539150027 11.682341700202528 0.0018336208041837888 2.7366904721979988 3.0004624860166498 VKEGMNIVEAMER ddPTM_PC-9_AZD4547_30min_R2 1 VKEGMNIVEAMER 13 1 P62937;P62937-2 P62937 PPIA Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed 0 115.12 0.00038155 8475500.0 25790.0 20082.0 35018.0 52818.0 42433.0 37719.0 31255.0 34467.0 30572.0 40161.0 False True 33990.68353467553 26573.113775086098 34553.638439645256 40641.62612996537 36541.91039689576 35360.424967268176 34036.63445104209 29140.917122866784 32187.973506025006 38754.97561405702 0.8770663120310827 0.6856697328290313 0.8915923153648464 1.0486815044007933 0.9428959718824195 0.9124099398076363 0.8782519898863382 0.751927118031702 0.8305507356415401 1.0 15.242093924333947 -5.416076791568338 9.135465481942832 0.9045346368119721 0.7820056149860218 0.2426823430313555 0.08899525140776858 0.5245680814081684 41.29903232959793 0.024978568754880626 0.05208620334494973 3.8363940471254264e-06 5.416076791568338 -0.12252902182595027 VKEGMNIVEAMER ddPTM_PC-9_Lapatinib_30min_R1 1 VKEGMNIVEAMER 13 1 P62937;P62937-2 P62937 PPIA Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed 0 96.37100000000001 0.0042522 12381000.0 47752.0 37793.0 45272.0 39702.0 41857.0 40798.0 36107.0 38508.0 42856.0 28760.0 False True 47071.04772335569 37705.49263049501 41549.91091497369 42621.817521989506 39395.053554028214 39053.16464478309 37976.443787092125 40297.222260365495 38029.10598631327 33731.127679708865 1.3954780335337416 1.1178248467861616 1.23179726777911 1.2635752331407788 1.1679139199881097 1.1577782105481083 1.1258575209134514 1.1946598003779902 1.1274187553827284 1.0 15.041792930064654 -1.5228790193022523 0.023415577519821717 2.0060868009471477e-10 2.754774180552728 0.5783108991151564 0.06457421793439903 1714.0480843151054 3.100017218228401 128.5306758517555 256.4479729826505 0.029999981071242687 1.5228790193022523 2.7547741803521193 VKELQAEQEDR ddPTM_PC-9_AZD4547_30min_R2 2 VKELQAEQEDR 11 1 Q00341;A0A024R4E5;Q00341-2;H0Y394 Q00341 HDLBP Vigilin 0 ; 109.72 0.0026256 11832600.0 51915.0 51068.0 76894.0 93938.0 83147.0 67510.0 58507.0 75050.0 56927.0 64049.0 False True 68422.89010091811 67574.73231083041 75874.33531835297 72282.04542763247 71603.47427169174 63288.589027818125 63714.00965692267 63452.74697743207 59936.04500122615 61806.66400499832 1.1070471316067914 1.093324375270693 1.2276076785541603 1.169486277754564 1.1585073458405901 1.0239767838416254 1.030859870575932 1.0266327749431783 0.9697343476810059 1.0 15.91547477768956 -6.783610356817461 5.846566967526821 1.0121441934085254 1.1535764472410341 0.7784891032535368 0.037599879448250405 0.08710287345781219 9.18905203699869 0.014192669254416182 0.01293476165337776 1.645847693474968e-07 6.783610356817461 0.1414322538325088 VKEPS(ph)VQEATSTSDILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VKEPSVQEATSTSDILK 17 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 VKEPS(0.585)VQEAT(0.221)S(0.085)T(0.08)S(0.029)DILK 71.434 0.0063103000000000005 8038400.0 38120.0 38728.0 33036.0 45560.0 46283.0 36555.0 49129.0 29613.0 29158.0 27160.0 True False 44572.96309568078 42572.659895564575 33823.70352972767 43007.42090751294 37214.178395295465 34637.99144860032 44475.14545684193 28835.690127567064 29584.380588483495 32083.8930015583 1.3892629268373353 1.3269169016832478 1.0542269146728818 1.3404676578812955 1.1599022099184781 1.0796068746058332 1.3862141185510684 0.8987590790857746 0.9220944785923141 1.0 14.969561585970892 -7.77521795967219 24.999890899902372 0.9328199434490304 1.2373428235100572 0.596187105008785 0.11580076595862902 168.72589461238047 306132.19461861264 0.0626647781000168 0.030351554355257524 1.6779616869764915e-08 7.77521795967219 0.3045228800610268 VKEPSVQEAT(ph)STSDILK ddPTM_PC-9_AZD4547_30min_R2 2 VKEPSVQEATSTSDILK 17 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 VKEPS(0.092)VQEAT(0.706)S(0.136)T(0.049)S(0.018)DILK;VKEPS(0.017)VQEAT(0.779)S(0.032)T(0.023)S(0.149)DILK 75.143 0.0066021000000000005 18891700.0 75946.0 69227.0 79570.0 82724.0 80054.0 94771.0 86354.0 91737.0 82031.0 76707.0 True False 100095.24822506675 91603.27394223114 78514.8498098856 63653.25987305952 68939.88393262544 88844.95438831802 94039.33871013556 77561.15455654472 86366.99119039442 74021.51127779366 1.3522454013323446 1.2375223412888083 1.060703144998337 0.8599292121201989 0.9313493164696747 1.2002585850333938 1.270432568678819 1.0478191166006758 1.1667823271841842 1.0 16.175656970614774 -5.076053300262501 3.128564569353353 1.0689903154281661 1.3400737053425882 0.39494176728168295 0.11663394381755819 0.29682957313142316 5.403518424067524 0.03438302354681907 0.1363068345461841 8.393569672686996e-06 5.076053300262501 0.27108338991442205 VKEPSVQEAT(ph)STSDILK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VKEPSVQEATSTSDILK 17 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 VKEPS(0.081)VQEAT(0.695)S(0.15)T(0.054)S(0.02)DILK 73.597 0.0075322 8100100.0 33335.0 35748.0 30745.0 41218.0 43462.0 32046.0 39549.0 36474.0 32704.0 29933.0 True False 38977.9571037387 39296.825189698444 31478.07740106182 38908.689090558975 34945.93309457752 30365.451346241156 35802.63241003565 35516.59614739748 33182.234130110584 35359.61595050235 1.1023297639403502 1.1113476244964746 0.8902267899381585 1.1003708056395392 0.9883006971426409 0.8587607792106055 1.0125288821053218 1.0044395334246525 0.9384217910217196 1.0 15.109814984897724 -5.235307029421106 24.533842891965218 0.9765553050535064 1.1068387620939482 0.40743915499914063 0.0639628854723075 596.5284995017699 560036.193126076 0.016194396306062394 0.04281598929501474 5.8169183871531555e-06 5.235307029421106 0.13028345704044175 VKEPSVQEAT(ph)STSDILK ddPTM_PC-9_Lapatinib_30min_R1 1 VKEPSVQEATSTSDILK 17 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 VKEPS(0.002)VQEAT(0.325)S(0.325)T(0.086)S(0.262)DILK 68.57600000000001 0.012426999999999999 11898000.0 25886.0 33289.0 30419.0 37217.0 36201.0 32257.0 34179.0 38783.0 35281.0 25586.0 True False 25516.860893088982 33211.92136577006 27918.067240735654 39954.06233227248 34071.72835390438 30877.44330473965 35948.62138086859 40584.99976430231 31307.282254599537 30008.506008798024 0.8503209351911034 1.1067502446150717 0.9303384591205744 1.3314245741043746 1.135402353716479 1.028956366427801 1.1979477209005014 1.3524498604630109 1.0432802701147712 1.0 14.87308387484851 -3.9556133909534843 0.8472030223594432 1.1583859295430936 2.0601555275864797e-14 0.2851597146603244 0.13030207350515705 10.117095803305958 2.0245631531841592 0.044835142848811016 15.24570588081472 0.00011076093393274392 3.9556133909534843 -1.158385929543073 VKEPSVQEATS(ph)TSDILK ddPTM_PC-9_Lapatinib_30min_R1 1 VKEPSVQEATSTSDILK 17 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 VKEPSVQEAT(0.105)S(0.666)T(0.18)S(0.049)DILK 101.78 0.00048487 11138000.0 28874.0 39097.0 37352.0 41722.0 43065.0 40140.0 38656.0 42943.0 42802.0 32543.0 True False 28462.251465156907 39006.473298612545 34281.06274288958 44790.375060511935 40532.001369047626 38423.30577091015 40657.41853473935 44938.288551128964 37981.18803495849 38168.01418917819 0.7457095180295451 1.0219675853524517 0.89816207290683 1.1735055127183271 1.0619363419891963 1.0066886262530352 1.065222265251279 1.1773808385312945 0.9951051644108676 1.0 15.22007650731456 -4.133875285893 1.0411538059600405 1.065893802969764 1.7000166318353072e-17 0.5626896999915318 0.0791129967651911 4.287699551706024 1.4537339105850242 0.02408192735362909 7.031278268102591 7.347248250054796e-05 4.133875285893 -1.065893802969764 VKESSIIAPAPAEDVDT(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 5 VKESSIIAPAPAEDVDTPPR 20 1 Q15910-5;Q15910-3;Q15910-4;Q15910;Q15910-2 Q15910-5 EZH2 Histone-lysine N-methyltransferase EZH2 1 VKESSIIAPAPAEDVDT(1)PPR;VKESSIIAPAPAEDVDT(1)PPR;VKESSIIAPAPAEDVDT(1)PPR;VKESSIIAPAPAEDVDT(1)PPR;VKESSIIAPAPAEDVDT(1)PPR 119.52 9.385e-06 65016300.0 347869.0 294778.0 452135.0 529787.0 497879.0 465110.0 377252.0 481059.0 391945.0 431629.0 True False 458484.10587530176 390059.22380202817 446139.3944802386 407652.7922775566 428757.09486711037 436026.59817402676 410826.6971660389 406722.3851860968 412662.4125284239 416517.8000876419 1.1007551316626312 0.9364767213308856 1.0711172352930987 0.9787163770474636 1.0293848060680555 1.0468378496243855 0.9863364712854876 0.9764826019452615 0.9907437627913938 1.0 18.66801862560851 -7.291270151355987 22.583275215667992 0.9864308900522704 1.0229799744107861 0.15730832419754914 0.04326681102515061 418.7606455215821 317017.71923317324 0.01678599703701625 0.011320565419865598 5.113636446280251e-08 7.291270151355987 0.03654908435851578 VKESSIIAPAPAEDVDT(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VKESSIIAPAPAEDVDTPPR 20 1 Q15910-5;Q15910-3;Q15910-4;Q15910;Q15910-2 Q15910-5 EZH2 Histone-lysine N-methyltransferase EZH2 1 VKESSIIAPAPAEDVDT(1)PPR 62.532 0.0070922 5542300.0 23913.0 25138.0 23102.0 30697.0 26206.0 27745.0 29012.0 27044.0 26438.0 22817.0 True False 27960.99859672125 27633.534508745666 23652.839294822894 28977.14661101676 21071.122421345044 26290.003357718953 26263.773331309363 26334.12365548657 26824.605734217934 26953.541480727385 1.0373775415269355 1.0252283370073836 0.8775410575168908 1.0750775229940124 0.7817570999496132 0.9753821543828338 0.9744089974257658 0.9770190560790049 0.9952163708579207 1.0 14.718187223622182 -10.640926074486599 14.858763867393474 0.9999997200948098 0.9659832444002081 0.012567048507604262 0.07962768277859146 0.0 0.0 0.07446185044481966 0.01805965143899629 2.2859878906269147e-11 10.640926074486599 -0.034016475694601644 VKESSIIAPAPAEDVDT(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 3 VKESSIIAPAPAEDVDTPPR 20 1 Q15910-5;Q15910-3;Q15910-4;Q15910;Q15910-2 Q15910-5 EZH2 Histone-lysine N-methyltransferase EZH2 1 VKESSIIAPAPAEDVDT(1)PPR;VKESSIIAPAPAEDVDT(1)PPR;VKESSIIAPAPAEDVDT(1)PPR 102.33 0.0001669 43652000.0 214771.0 198341.0 214577.0 196616.0 191286.0 190272.0 168338.0 159439.0 201150.0 177217.0 True False 211708.3261558223 197881.75360053443 196935.3073511729 211075.79653174864 180034.93356274575 182134.51010569572 177053.71795584026 166847.11800068585 178494.36879659595 207848.72232319057 1.0185692930391474 0.9520470050946083 0.9474934709723736 1.0155260719069525 0.866182536752878 0.8762840015080247 0.8518393376531506 0.8027334310058927 0.8587705846901931 1.0 17.665174353966755 -6.274131298732002 23.91782116386315 0.8649143085703681 0.9786034264737689 0.498064073446324 0.05204595198651593 331.6720452725892 625031.8349640344 0.015539672784471171 0.017750720530864777 5.319474131527793e-07 6.274131298732002 0.11368911790340075 VKGDVDVSLPK ddPTM_PC-9_AZD4547_30min_R2 2 VKGDVDVSLPK 11 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ; 107.97 0.0038930999999999996 0.0 184801.0 170894.0 210497.0 275170.0 243180.0 232420.0 203165.0 215610.0 198491.0 211030.0 False True 243563.87390040988 226132.1434856868 207705.67224370362 211733.80783412023 209418.65459234847 217886.74065835465 221246.29141724383 182292.42872490507 208982.82903259224 203641.903932533 1.1960400546102885 1.1104401359388432 1.019955462175 1.03973594699973 1.0283672002090951 1.0699504200792633 1.0864477651443645 0.8951616794218293 1.0262270436335574 1.0 17.635674933567913 -1.5228787453264374 0.6302610872194341 1.0120193313194519 15.563554454840856 0.5716192545551229 0.048604279107846524 152.09425455401515 1.056981094271605 0.021977286147681355 3073.3707815337293 0.029999999996815536 1.5228787453264374 14.551535123521404 VKGDVDVSLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VKGDVDVSLPK 11 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 85.522 0.029285000000000002 0.0 71899.0 69355.0 64795.0 80524.0 74872.0 68853.0 77884.0 69567.0 67666.0 61818.0 False True 84070.08063001992 76240.1060487729 66339.95853640579 76012.50134233023 60201.36907314916 65242.22747122084 70506.26368867003 67740.93996232917 68655.4872385047 73025.11404898134 1.151248878209628 1.044025840173767 0.9084540216110925 1.0409090397496006 0.8243926744540145 0.893421781271849 0.9655070670807608 0.9276389478404946 0.9401626842027837 1.0 16.156105085774342 -4.827901006298988 1.5532935218622748 0.9312585556528721 1.2273639503065483 0.585786662973965 0.05677353835058131 0.6630333388390552 1.6353971253105815 0.015872810338939544 0.29480265730779703 1.4862743871732401e-05 4.827901006298988 0.29610539465367625 VKGDVDVSLPK ddPTM_PC-9_Lapatinib_30min_R1 2 VKGDVDVSLPK 11 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 ; 121.04 0.0016390999999999999 0.0 336330.0 258620.0 278660.0 246550.0 278310.0 265360.0 262170.0 227250.0 262040.0 233080.0 False True 331533.87252463127 258021.1812795658 255749.65045870683 264682.1094666897 261940.35297851262 254011.17138437284 275743.87979233766 237808.86461691168 232526.29579647002 273367.5674404227 1.2127769055737938 0.943861715914045 0.9355522780310963 0.9682279135924714 0.9581983533419687 0.9291927852404497 1.0086927369408327 0.8699234764516802 0.8505994254316449 1.0 18.06048256497268 -4.7614339449799505 7.392011677092072 0.9391558353322642 1.2174948796868996 0.7479353698277225 0.047426581533868396 0.051602826180648716 19.225240204527154 0.012045366792090539 0.07194716007789936 1.732072454268067e-05 4.7614339449799505 0.2783390443546354 VKGEY(ph)DVTVPK ddPTM_PC-9_AZD4547_30min_R2 1 VKGEYDVTVPK 11 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VKGEY(1)DVTVPK 99.539 0.021091 3937500.0 20557.0 34881.0 36377.0 37491.0 40097.0 38987.0 30843.0 38420.0 37993.0 38684.0 True False 27093.698387837365 46155.60111486793 35894.617211690434 28848.02918017593 34530.22367460066 36549.13672681897 33587.967249191825 32483.071803770014 40001.23241575324 37329.684934493205 0.7257949922529984 1.2364315743854415 0.9615569291484497 0.7727905882623699 0.9250071018599517 0.9790904153344998 0.8997656237424073 0.8701673175321969 1.0715663013483268 1.0 15.188035711781046 -9.825047374253165 7.227881702563242 0.9999984395032187 0.9403330024064223 0.017834812919607868 0.13702188595611103 0.0 0.0 0.12885061114307703 0.03125086350989968 1.4960724507492498e-10 9.825047374253165 -0.05966543709679639 VKGEY(ph)DVTVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VKGEYDVTVPK 11 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VKGEY(0.998)DVT(0.002)VPK 105.36 0.011983 4729700.0 59370.0 39786.0 49369.0 51894.0 63570.0 47047.0 54412.0 54828.0 56666.0 47060.0 True False 69420.1683890496 43735.69114348616 50546.144192975116 48986.54742261802 51113.91484106328 44579.7724984899 49257.70145123418 53388.82309506793 57494.633048460324 55591.60547324498 1.2487527172148323 0.7867319313980812 0.9092405906014329 0.881186053282706 0.9194538349079212 0.8019155431649689 0.8860636607255538 0.960375629388196 1.0342322830761064 1.0 15.762579426950458 -8.008288905742743 4.016614087747491 1.0143521084400875 0.9079527768681376 0.090461469095236 0.12004465970816187 0.47181536802681945 17.23888990722885 0.07825143322837924 0.03048760609437873 9.810950719591624e-09 8.008288905742743 -0.10639933157194992 VKPAS(ph)PVAQPK ddPTM_PC-9_AZD4547_30min_R2 1 VKPASPVAQPK 11 1 H0Y3K4;Q96EV2 H0Y3K4 RBM33 RNA-binding protein 33 1 VKPAS(1)PVAQPK 57.288000000000004 0.036315 326430000.0 343920.0 283470.0 361270.0 396530.0 369160.0 352510.0 348840.0 348380.0 331620.0 335500.0 True False 453279.4060196057 375096.13394202024 356479.32375037513 305116.13482742955 317908.5061654377 330467.49397417 379886.084207375 294545.8759759861 349148.75618435186 323754.2471182518 1.4000724625368222 1.1585828982345852 1.1010799917635379 0.9424312964023769 0.9819438941578458 1.020735625603905 1.173377917320791 0.9097822765191486 1.0784376090572942 1.0 18.304539593124034 -4.690750553421817 1.4078761222745315 1.0189089282678516 1.6152945901280393 0.7257433825757105 0.07124983417479404 0.7869926514666044 1.2145119649797635 0.020543255180868063 0.7087246569278888 2.0382124336594503e-05 4.690750553421817 0.5963856618601877 VKPAS(ph)PVAQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VKPASPVAQPK 11 1 H0Y3K4;Q96EV2 H0Y3K4 RBM33 RNA-binding protein 33 1 VKPAS(1)PVAQPK;VKPAS(1)PVAQPK 58.071000000000005 0.034744 367630000.0 177032.0 210357.0 167360.0 231940.0 206320.0 185396.0 196603.0 172297.0 173280.0 163924.0 True False 207000.02105861934 231239.8527590184 171350.49711633488 218945.15375962562 165893.07708051265 175673.50738899488 177979.34055754228 167774.38631376185 175813.89218644684 193642.1235783297 1.0689823951186235 1.194160900975041 0.8848823486849561 1.130669038914256 0.8566993276822212 0.9072070897731797 0.9191147941813823 0.8664147201726791 0.9079320601198055 1.0 17.5630332951649 -5.642457395584883 0.9221048014122014 0.9049251908141551 1.1371711862897949 0.4045543677927703 0.0872432733029477 0.7181660558872152 1.0542527941380289 0.03334960038429349 0.12914965338697615 2.2779416976403503e-06 5.642457395584883 0.23224599547563973 VKPAS(ph)PVAQPK ddPTM_PC-9_Lapatinib_30min_R1 2 VKPASPVAQPK 11 1 H0Y3K4;Q96EV2 H0Y3K4 RBM33 RNA-binding protein 33 1 VKPAS(1)PVAQPK;VKPAS(1)PVAQPK 132.31 0.00055409 274938000.0 802230.0 650707.0 581779.0 618131.0 643809.0 615555.0 589727.0 527420.0 598321.0 467876.0 True False 790790.0530890374 649200.3279208175 533947.3763518825 663590.4157645684 605941.4203971941 589229.1475787895 620260.178503628 551925.8586413724 530931.7883805514 548747.743194418 1.4410811942216322 1.1830578548562882 0.9730288333280819 1.2092813574077192 1.1042258085105467 1.0737705163919538 1.1303193246735113 1.005791578163864 0.9675334340144073 1.0 19.065783575802044 -4.830739412989981 3.04217565726682 1.0682700121866406 1.4797759784273117 0.7147722722489009 0.07333868450414163 0.17997679616210316 2.608114448739391 0.019062822296653115 0.1708850446545935 1.4765922579669368e-05 4.830739412989981 0.41150596624067104 VKPET(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 1 VKPETPPR 8 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 VKPET(1)PPR 115.91 0.037223 151290000.0 565580.0 542050.0 526280.0 462710.0 456420.0 617090.0 567390.0 663570.0 574670.0 532350.0 True False 745422.6752051897 717257.0621345185 519301.1833347563 356039.3582982369 393053.9613826774 578503.2647485757 617886.6108199258 561030.5038216473 605045.8829879422 513712.5885347288 1.4510500459631943 1.3962224756460866 1.0108788356072176 0.693071118451222 0.7651242546027379 1.1261224226539794 1.2027865865275646 1.0921097055882631 1.1777906488796097 1.0 18.97060190181859 -5.248484228929304 5.431189626182012 1.0020964874499634 1.430863168687015 0.5279861702525768 0.15716396655724144 0.14543733577991533 15.13401912606319 0.04709491327487497 0.11889618769114443 5.643074333642404e-06 5.248484228929304 0.42876668123705164 VKPPGGHS(ph)PQVNHLK ddPTM_PC-9_Lapatinib_30min_R1 1 VKPPGGHSPQVNHLK 15 1 Q92610 Q92610 ZNF592 Zinc finger protein 592 1 VKPPGGHS(1)PQVNHLK 74.812 0.0065792 13940000.0 70342.0 66308.0 67963.0 55729.0 70440.0 59441.0 52623.0 54229.0 62136.0 56002.0 True False 69338.91018085688 66154.46789995133 62375.344484766734 59827.49656649421 66296.85769036833 56898.84699373871 55347.56145368352 56748.67731269759 55137.58935891266 65681.87108202554 1.055678059083675 1.0071952398757884 0.9496584591335787 0.9108677262220468 1.0093631103714262 0.8662793257317789 0.8426611566007884 0.8639930071697881 0.8394643521962878 1.0 16.003207605360508 -4.971781270714964 0.5621904580410038 0.8785440715774596 1.1440939214366637 0.4707719369564638 0.055280467234982464 2.784298295013424 0.779231860868486 0.031736964372572625 0.47024671814831037 1.0671334399747552e-05 4.971781270714964 0.26554984985920405 VKPPPQIS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 1 VKPPPQISPSK 11 1 Q9H6U6-3;Q9H6U6-8;K7ESE9;Q9H6U6-6;Q9H6U6-2;Q9H6U6-7;Q9H6U6 Q9H6U6-3 BCAS3 Breast carcinoma-amplified sequence 3 1 VKPPPQIS(0.901)PS(0.099)K 57.794 0.035301 6350200.0 46440.0 49203.0 65145.0 86992.0 81680.0 65253.0 66519.0 67548.0 60240.0 66295.0 True False 61206.95398799277 65106.90753289316 64281.13473501316 66937.33841300225 70340.14189942858 61172.719594611466 72439.06213562217 57110.00869862209 63424.16341760254 63974.03222862756 0.9567468526800698 1.0177083617336637 1.0048004244173336 1.0463204534893868 1.099510839774021 0.9562117231565944 1.1323197805750724 0.8927060982263064 0.9914048123610542 1.0 15.965198797515301 -7.78221450968614 24.999993546416153 0.9565416556031858 1.029438781391836 0.22482573763785574 0.058608564469678576 349.1236339856289 420116.2310615285 0.030355357843376497 0.01460702875472026 1.651146051491202e-08 7.78221450968614 0.07289712578865015 VKPPPQIS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VKPPPQISPSK 11 1 Q9H6U6-3;Q9H6U6-8;K7ESE9;Q9H6U6-6;Q9H6U6-2;Q9H6U6-7;Q9H6U6 Q9H6U6-3 BCAS3 Breast carcinoma-amplified sequence 3 1 VKPPPQIS(0.909)PS(0.091)K;VKPPPQIS(0.765)PS(0.235)K 76.156 0.009873999999999999 14015700.0 132342.0 132396.0 119040.0 147507.0 160888.0 156372.0 151110.0 143468.0 130825.0 119257.0 True False 154744.88672635314 145539.39990531863 121878.36506171376 139242.66101414614 129363.15134417168 148171.57704282683 136795.76685834018 139702.11701691127 132738.06812841582 140877.3500621076 1.0984369500003504 1.0330929694599997 0.8651381148778147 0.9883963671431867 0.9182679209052431 1.0517771449952988 0.9710273993515067 0.9916577572996779 0.9422243396109915 1.0 17.10408015152229 -5.008846977431185 14.73637404148426 0.9668268595594158 1.082122685069112 0.43599645499551953 0.047944219919018975 1.640027660760368 2748.4026579175766 0.01177243074501801 0.03719952366391508 9.798351670508388e-06 5.008846977431185 0.11529582550969608 VKPPPS(ph)PTTEGPSLQPDLAPEEAAGTQRPK ddPTM_PC-9_AZD4547_30min_R2 2 VKPPPSPTTEGPSLQPDLAPEEAAGTQRPK 30 2 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 VKPPPS(0.872)PT(0.061)T(0.061)EGPS(0.007)LQPDLAPEEAAGTQRPK;VKPPPS(0.741)PT(0.129)T(0.129)EGPSLQPDLAPEEAAGTQRPK 114.57 2.4609e-17 85216000.0 198054.0 148445.0 208635.0 236580.0 249960.0 245030.0 198216.0 235469.0 213992.0 213696.0 True False 261031.0522208858 196426.94324980848 205868.36358031275 182040.13612456387 215257.36862366722 229708.23536492782 215856.84000472704 199082.67658932618 225303.18024667358 206214.56808400026 1.2658225587367637 0.9525366955151061 0.9983211442969127 0.8827704939372223 1.043851414687557 1.113928261709219 1.046758441997168 0.9654151907843439 1.0925667489936874 1.0 17.65378673032488 -7.570811791488226 0.004770071895940059 1.5881885394162148e-06 2.051733889641946 0.020992009718312166 0.09914812168129654 40459.374712916164 157.49183687478262 33726.442105736896 34002.99874358587 2.686508435143143e-08 7.570811791488226 2.0517323014534066 VKPPPS(ph)PTTEGPSLQPDLAPEEAAGTQRPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VKPPPSPTTEGPSLQPDLAPEEAAGTQRPK 30 2 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 VKPPPS(0.452)PT(0.452)T(0.093)EGPS(0.002)LQPDLAPEEAAGTQRPK;VKPPPS(0.716)PT(0.073)T(0.21)EGPS(0.001)LQPDLAPEEAAGTQRPK;VKPPPS(0.568)PT(0.216)T(0.216)EGPSLQPDLAPEEAAGTQRPK 78.531 4.823699999999999e-07 69208000.0 132679.0 129754.0 145305.0 169891.0 191697.0 198450.0 191806.0 208011.0 187303.0 137925.0 True False 155138.9341703 142635.11960568823 148769.6222722814 160372.5580640533 154135.348958429 188042.9326487413 173636.7471248147 202550.93165587212 190041.95203253764 162929.7106863006 0.9521832053639333 0.8754395929684864 0.9130908147177494 0.98430517913844 0.9460235847051619 1.1541353130540621 1.065715678211257 1.2431798399609075 1.166404526418377 1.0 17.313890181746615 -6.740549314414361 7.131617952288799 1.1375342536017876 0.9318278472105196 0.678401349427399 0.06574144904513987 0.09236968805598857 19.181791286277114 0.0220174372445296 0.02138719836317442 1.817400677376853e-07 6.740549314414361 -0.20570640639126803 VKPPPSPT(ph)TEGPSLQPDLAPEEAAGTQRPK ddPTM_PC-9_AZD4547_30min_R2 2 VKPPPSPTTEGPSLQPDLAPEEAAGTQRPK 30 2 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 VKPPPS(0.008)PT(0.43)T(0.43)EGPS(0.131)LQPDLAPEEAAGTQRPK;VKPPPS(0.205)PT(0.639)T(0.155)EGPS(0.001)LQPDLAPEEAAGTQRPK 112.74 3.4566e-16 84797000.0 226230.0 213690.0 272140.0 348280.0 319640.0 318890.0 275760.0 329020.0 271980.0 282620.0 True False 298166.4341236771 282761.11356429354 268531.24578688265 267989.42687236087 275263.50338801846 298949.75788891874 300302.10578209464 278177.51912744483 286356.3075418248 272725.5598228325 1.0932837916525735 1.0367972614960632 0.9846207519431821 0.9826340701122831 1.009305851519141 1.0961559968311072 1.101114636916233 1.0199906430044694 1.0499797222080947 1.0 18.057090390317526 -6.727580028934181 24.99841169947963 1.0576768203566698 1.017998719126789 0.1276576099800114 0.04078620592785569 348.75771108929456 257487.30923582322 0.014258534098410587 0.014257647477018522 1.8724920006985597e-07 6.727580028934181 -0.0396781012298808 VKPPPSPT(ph)TEGPSLQPDLAPEEAAGTQRPK ddPTM_PC-9_Lapatinib_30min_R1 2 VKPPPSPTTEGPSLQPDLAPEEAAGTQRPK 30 2 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 VKPPPS(0.027)PT(0.588)T(0.384)EGPSLQPDLAPEEAAGTQRPK;VKPPPS(0.102)PT(0.299)T(0.299)EGPS(0.299)LQPDLAPEEAAGTQRPK 115.5 3.3148e-17 68611000.0 91026.0 72310.0 78407.0 69776.0 93967.0 83524.0 76108.0 71165.0 84004.0 74250.0 True False 89727.95254787586 72142.57063771322 71960.67911977264 74907.55980591252 88440.04580622994 79951.8732239536 80048.49984069604 74471.58570060544 74542.5849186638 87084.01356809378 1.0303607846199543 0.8284249620775991 0.8263362719668895 0.8601757858500618 1.0155715404306191 0.9181004635418724 0.9192100428180604 0.8551694237470316 0.8559847194040564 1.0 16.410120280200843 -4.742749751651512 24.84647009613669 0.8947338536321876 1.0303612609981652 0.2819446402868916 0.06337507045886742 1629.0157219404148 2165532.8698246665 0.016413203800853808 0.5588552415377114 1.8082157525557252e-05 4.742749751651512 0.13562740736597756 VKPPPSPTT(ph)EGPSLQPDLAPEEAAGTQRPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VKPPPSPTTEGPSLQPDLAPEEAAGTQRPK 30 2 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 VKPPPS(0.215)PT(0.215)T(0.569)EGPS(0.002)LQPDLAPEEAAGTQRPK 89.803 2.7390999999999998e-09 37129000.0 119850.0 105560.0 130980.0 151610.0 155370.0 185650.0 194260.0 182930.0 188010.0 137460.0 True False 140138.23785459972 116039.29917826381 134103.05994441648 143115.78322625192 124926.36383287735 175914.18718185314 175858.28647939328 178128.2813303566 190759.2905700244 162380.40986723884 0.8630242895012756 0.7146139073865917 0.8258573805427532 0.8813611404433728 0.7693438139182943 1.0833461211588236 1.0830018634832481 1.096981350619777 1.1747678844140617 1.0 17.309018065751992 -6.767759976351331 24.999744319398086 1.0933922428600535 0.8102463251964285 0.8473516400748837 0.058712001481335326 53.822567298699354 212882.06440913575 0.020099352308144712 0.018154996122382503 1.7070255584839023e-07 6.767759976351331 -0.28314591766362507 VKPYVNGT(ph)SPVYSR ddPTM_PC-9_AZD4547_30min_R2 2 VKPYVNGTSPVYSR 14 1 E9PDR5;E7EPI0;Q9P2D0-2;Q9P2D0 E9PDR5 IBTK Inhibitor of Bruton tyrosine kinase 1 VKPYVNGT(0.498)S(0.498)PVYS(0.004)R;VKPYVNGT(0.597)S(0.4)PVY(0.001)S(0.001)R 65.175 0.0285 20403500.0 43551.0 46701.0 90263.0 120858.0 95030.0 80631.0 55734.0 98463.0 52823.0 77828.0 True False 57399.31208292573 61796.18496216987 89066.05364320354 92996.05533748634 81836.72483720236 75589.13082361138 60694.21802893553 83247.80580464898 55615.115939708165 75103.26540899943 0.7642718564943745 0.822816220115577 1.1859145292573523 1.238242502919758 1.0896560141763967 1.0064692981319256 0.8081435300902735 1.1084445576539952 0.7405152843466637 1.0 16.196588015477467 -7.022426633140111 23.17142582488444 0.9210262187522213 1.0322901130948678 0.08428762635595688 0.1648362773056602 854.8522163089248 883238.7785445214 0.06697464150453178 0.05238922983825988 9.496714169091927e-08 7.022426633140111 0.1112638943426465 VKPYVNGT(ph)SPVYSR ddPTM_PC-9_Lapatinib_30min_R1 1 VKPYVNGTSPVYSR 14 1 E9PDR5;E7EPI0;Q9P2D0-2;Q9P2D0 E9PDR5 IBTK Inhibitor of Bruton tyrosine kinase 1 VKPYVNGT(0.499)S(0.499)PVY(0.001)S(0.001)R 71.263 0.018379 7117900.0 35021.0 25375.0 24844.0 31481.0 28455.0 28815.0 28261.0 21264.0 32141.0 23828.0 True False 34521.594117935165 25316.24574653536 22801.422220613316 33796.21775753744 26781.33284468245 27582.64962104577 29724.216297865005 22252.00306804849 28520.942120265405 27946.638051185768 1.2352682299283015 0.905878041579359 0.8158914206013362 1.2093124652646179 0.9583024904688356 0.9869755915014417 1.06360615697042 0.7962318410999116 1.0205500235136609 1.0 14.77038711848156 VKS(ph)PGGPGSHVR ddPTM_PC-9_AZD4547_30min_R2 2 VKSPGGPGSHVR 12 1 O75382-3;O75382-2;O75382;A0A1W2PPI7;O75382-4 O75382-3 TRIM3 Tripartite motif-containing protein 3 1 VKS(1)PGGPGSHVR;VKS(1)PGGPGSHVR 68.676 0.014306999999999999 5417700.0 19170.9 20805.3 31689.0 39751.0 30469.0 28318.0 23077.0 33867.0 23883.0 27342.0 True False 25266.84742050839 27530.20635518367 31268.78315477524 30587.021096827848 26238.90528322338 26547.270983406244 25130.808293927297 28633.633336238418 25145.406621889146 26384.764902257102 0.9576301897746651 1.0434129868948947 1.1851075145301118 1.1592682826675957 0.9944718241919508 1.0061590877065287 0.9524742171107033 1.0852335975822522 0.9530275033732843 1.0 14.687417508206162 -6.292112684805257 24.491113851197625 1.000898262983273 1.090341252100964 0.28858517042893683 0.06735339663264998 731.0002802742448 583665.2173005923 0.022149982142121487 0.025118948652238515 5.103725582878042e-07 6.292112684805257 0.08944298911769111 VKS(ph)PGGPGSHVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VKSPGGPGSHVR 12 1 O75382-3;O75382-2;O75382;A0A1W2PPI7;O75382-4 O75382-3 TRIM3 Tripartite motif-containing protein 3 1 VKS(1)PGGPGSHVR 64.12100000000001 0.018858 1973400.0 13019.0 14151.0 17056.0 17251.0 18353.0 17679.0 18691.0 22081.0 16343.0 13324.0 True False 15222.859563029073 15555.817759299067 17462.67972524021 16284.482398496608 14756.86139811287 16751.88211789919 16920.45316887852 21501.397146753396 16581.98545708162 15739.535727274028 0.9671733542083049 0.9883276119983255 1.1094787055872466 1.0346227919720832 0.9375664983905246 1.064318694538806 1.0750287341422757 1.3660756911333165 1.0535244332745957 1.0 13.942105365513148 -7.532807455728948 24.999695276224713 1.1699904861775055 1.021408564691223 0.21371230690146248 0.10087024278989329 254.5942536706437 641038.9473895482 0.04529192272630165 0.02618824369477214 2.932192943594297e-08 7.532807455728948 -0.14858192148628246 VKS(ph)PGGPGSHVR ddPTM_PC-9_Lapatinib_30min_R1 1 VKSPGGPGSHVR 12 1 O75382-3;O75382-2;O75382;A0A1W2PPI7;O75382-4 O75382-3 TRIM3 Tripartite motif-containing protein 3 1 VKS(0.994)PGGPGS(0.006)HVR 57.802 0.029879000000000003 3396300.0 24995.0 19834.0 26916.0 22440.0 28126.0 23957.0 18802.0 23797.0 28438.0 19336.0 True False 24638.56671647839 19788.07559159734 24703.07037876461 24090.312457645563 26471.68397784358 22932.414956494646 19775.47556110745 24902.695495219632 25235.01297458412 22678.201836399516 1.0864426948053882 0.8725592855354433 1.0892869971337449 1.0622673098790198 1.1672743795478244 1.0112095801037941 0.8720036845852098 1.0980895079278157 1.1127431159061654 1.0 14.469018632503575 -5.328899550747423 24.99998330310706 1.0517667172739076 0.9794924009369032 0.09394211078565606 0.08957484672056605 395.3342158565358 146505.1053248964 0.024093686870244452 0.050155019347713596 4.68921827917053e-06 5.328899550747423 -0.07227431633700443 VKS(ph)PGSGHVK ddPTM_PC-9_Lapatinib_30min_R1 1 VKSPGSGHVK 10 1 A0A0J9YX34;Q9C040;Q9C040-2 A0A0J9YX34 TRIM2 Tripartite motif-containing protein 2 1 VKS(0.997)PGS(0.003)GHVK 65.234 0.023281 5931100.0 41994.0 32164.0 22952.0 25940.0 29113.0 19158.0 28989.0 33687.0 35807.0 24887.0 True False 41395.15785924359 32089.526234150282 21064.975157282115 27847.714133303285 27400.63057836024 18338.656999479244 30489.908575733614 35252.221000439706 31774.038595573995 29188.684790156953 1.418191952012957 1.0993823964610956 0.7216829161273369 0.9540585447239517 0.9387415286214033 0.6282796614962052 1.0445797333772113 1.2077358488015022 1.0885738368824647 1.0 14.833121585611758 -10.388225228189478 14.254965803338528 1.0000309635344582 0.9970041142682651 0.0 0.21446098967125152 0.0 0.0 0.2195316267535766 0.05324424030992166 4.0904846928422984e-11 10.388225228189478 -0.0030268492661931212 VKS(ph)PVEK ddPTM_PC-9_Lapatinib_30min_R1 1 VKSPVEK 7 1 Q96B01-3;Q96B01-2;Q96B01;H0YGT5 Q96B01-3 RAD51AP1 RAD51-associated protein 1 1 VKS(1)PVEK 56.434 0.043045 20333000.0 115870.0 219830.0 135920.0 171960.0 211380.0 128190.0 273570.0 275820.0 184680.0 197450.0 True False 114217.67255204437 219320.99714131473 124745.18226637275 184606.5120417436 198947.04398906973 122707.61252548516 287734.11601170927 288635.60413041525 163879.3936333847 231578.9694144128 0.4932126299761303 0.9470678520415975 0.538672326687576 0.797164407927684 0.859089426350508 0.5298737309168118 1.2424881099492515 1.2463808991821665 0.7076609505940107 1.0 17.821144716973066 -7.262222318577078 24.99905304521076 1.0696642308891198 0.710783415623304 0.4327562850613167 0.1979824990363388 67.07791283658929 2141726.3527482287 0.0767821006019892 0.05520505470211591 5.467360130122875e-08 7.262222318577078 -0.3588808152658157 VKT(ph)PEMIIQKPK ddPTM_PC-9_AZD4547_30min_R2 1 VKTPEMIIQKPK 12 2 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VKT(1)PEMIIQKPK 53.211000000000006 0.043175 104290000.0 82743.0 77673.0 97657.0 113010.0 108130.0 114730.0 104110.0 113120.0 83064.0 107450.0 True False 109053.55283868377 102779.27827169921 96362.00437204976 86957.290487095 93118.01595966217 107555.91496314015 113375.58831220587 95639.90323900247 87454.59346148306 103688.20820523443 1.0517449836034343 0.9912340086759321 0.929343905541471 0.8386420403270618 0.8980579139273943 1.037301317332538 1.0934279825512734 0.9223797468820985 0.8434381785089825 1.0 16.66189230946427 -4.928891489719662 3.1024869202390546 0.9459800775214171 1.0535154141797733 0.15888862898959988 0.07633316237120814 0.6042891072040152 10.43050881516915 0.02183005939588733 0.1343168898692056 1.1779002400253221e-05 4.928891489719662 0.10753533665835624 VKT(ph)PSFGISAPQVSIPDVNVNLK ddPTM_PC-9_AZD4547_30min_R2 1 VKTPSFGISAPQVSIPDVNVNLK 23 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VKT(0.735)PS(0.228)FGIS(0.036)APQVSIPDVNVNLK 69.952 0.00077656 3456100.0 6966.8 7392.6 8812.7 12416.0 10383.0 11114.0 11863.0 22369.0 16946.0 17635.0 True False 9182.097481557881 9782.11337982777 8695.837839884114 9553.683025287779 8941.499673625922 10419.039823065783 12918.784018323848 18912.38503848339 17841.73096405532 17017.60401767624 0.5395646456469669 0.5748231871929242 0.5109907264766368 0.5614000076253001 0.5254264739230246 0.6122506912397006 0.7591423566387527 1.111342408651596 1.0484279070968545 1.0 14.05474030757538 -7.527209217883221 2.321210459272724 1.0647411279918302 0.5491119561163177 0.9653462978458702 0.04215080774263276 0.047500852506745024 0.5096675712402823 0.023038170530186686 0.012218736181231439 2.9702348002325246e-08 7.527209217883221 -0.5156291718755125 VKVDPSHDASK ddPTM_PC-9_AZD4547_30min_R2 1 VKVDPSHDASK 11 1 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 63.602 0.022585 6828000.0 71885.0 64044.0 81687.0 121150.0 104090.0 89066.0 77665.0 105080.0 90751.0 84213.0 False True 94742.93469911406 84744.97055132013 80603.77700666235 93220.73924884152 89638.90022418575 83496.68894018138 84577.0345429588 88842.30049818227 95547.91258816156 81264.72850244233 1.1658555494499272 1.0428259850615658 0.9918666867168563 1.1471242317143762 1.103048048963724 1.0274653035685952 1.040759454951196 1.0932455215858157 1.1757611739918625 1.0 16.310341691799387 -7.986349454574524 24.09240034530743 1.103421512060808 1.0715418169092088 0.0 0.06449223076050786 528.9561363885033 933574.1939923086 0.03484457420862965 0.016721841821512352 1.0319307296846202e-08 7.986349454574524 -0.03187969515159916 VKVDPSHDASK ddPTM_PC-9_Lapatinib_30min_R1 1 VKVDPSHDASK 11 1 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 54.343 0.040319 10611000.0 115850.0 104170.0 114300.0 109950.0 130290.0 110770.0 110310.0 101330.0 123660.0 123810.0 False True 114197.95775571208 103928.8007651856 104902.69521075914 118036.08978244767 122626.59835999567 106032.62531748178 116021.31204902472 106038.16172335163 109732.10860247091 145210.39353354526 0.7864310189981756 0.7157118594350264 0.7224186413800017 0.8128625431703688 0.8444753531479654 0.7301999721733902 0.7989876566392093 0.7302380989612538 0.7556766835503517 1.0 17.14778519335355 -11.86480925487239 2.300023047540996 2.4307803961142143 0.7660558685601113 0.7434710519977898 0.04117662312402284 2948360.7806510376 283483.7002038988 22093056.242467765 0.010873415786558151 1.3651826025360915e-12 11.86480925487239 -1.664724527554103 VKVEPSHDASK ddPTM_PC-9_AZD4547_30min_R2 2 VKVEPSHDASK 11 1 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 82.48899999999999 0.0062575 14923100.0 105973.0 92363.0 142397.0 185094.0 174555.0 150341.0 145669.0 178806.0 139084.0 167529.0 False True 139670.20962466724 122217.53349309204 140508.72273945314 142423.43797379325 150321.0512886232 140940.15350364684 158633.2588017549 151175.64125312108 146435.69629438623 161663.860701859 0.863954436188107 0.7559978647205884 0.8691412052727094 0.8809850102271837 0.9298370745076152 0.8718098954940159 0.9812536834952054 0.9351232897494616 0.9058035336941718 1.0 17.302637680685663 -5.2204841867791885 0.2751917451770724 0.9850386842855987 0.6939260860874474 0.6034447460869068 0.04124608423241375 4.52672524942727 0.34783563572300724 0.05381458919543869 0.4389519665580074 6.01888178023491e-06 5.2204841867791885 -0.2911125981981513 VKVEPSHDASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VKVEPSHDASK 11 1 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 60.49 0.028547000000000003 5502900.0 62740.0 59767.0 77308.0 91667.0 111450.0 83833.0 84853.0 86750.0 75526.0 66734.0 False True 73360.64282851544 65700.27277365759 79151.3159122227 86531.19517842389 89612.17255051906 79436.64990043796 76815.10955747943 84472.9044192226 76630.42486884569 78832.34593394653 0.9305906345852523 0.8334177043102043 1.0040461814816906 1.097661044502319 1.1367436994150208 1.0076656854408186 0.9744110573830019 1.0715513209514567 0.9720683047166219 1.0 16.26650008719424 -5.4010964698298665 5.042339645972408 1.0411079075507768 0.883806619312831 0.5511844884254885 0.054981487013038566 0.15798033119152502 5.779736311718136 0.015098015760760674 0.03237584324410588 3.971033311119993e-06 5.4010964698298665 -0.15730128823794576 VKVEPSHDASK ddPTM_PC-9_Lapatinib_30min_R1 2 VKVEPSHDASK 11 1 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 125.97 0.00019567 18609600.0 417420.0 424470.0 480840.0 422850.0 450050.0 437880.0 388970.0 372100.0 453360.0 388560.0 False True 411467.51425454655 423487.16579435905 441307.1912960771 453947.79958625004 423578.9438323439 419152.8931481347 409108.96335517295 389389.12441783445 402297.82270755514 455722.0782763436 0.902891331951309 0.929266291850715 0.9683691274410333 0.9961066650604151 0.9294676822207667 0.9197555113710469 0.8977159169082322 0.8544442829950281 0.8827700958205656 1.0 18.797794740649074 -6.84602480497907 2.4033461234988085 0.8976627610116953 0.9495588892295947 0.12649937832113312 0.04234487009249931 0.4484044407428608 5.289339856345554 0.01679875820263091 0.014731534509404986 1.4255261715299568e-07 6.84602480497907 0.05189612821789946 VLAET(ph)PDSFEK ddPTM_PC-9_AZD4547_30min_R2 3 VLAETPDSFEK 11 0 Q99567;J3KMX1 Q99567 NUP88 Nuclear pore complex protein Nup88 1 VLAET(1)PDSFEK;VLAET(0.714)PDS(0.286)FEK;VLAET(0.943)PDS(0.057)FEK 122.46 0.0016312000000000002 24651300.0 117458.0 121370.0 160091.0 186995.0 161006.0 146108.0 136974.0 154491.0 127118.0 149604.0 True False 154807.20072182742 160600.47898029056 157968.08873839892 143886.19179395065 138653.09606585905 136971.84366281226 149164.42064620188 130617.96580000597 133837.19796345945 144366.40949591348 1.0723214718878873 1.1124504622720883 1.0942163713150355 0.9966736188588494 0.960424911515056 0.9487791802890926 1.0332349551882718 0.904767017868539 0.9270660566455933 1.0 17.139375576142143 -5.85570151588906 3.139140782660064 0.961242707254002 1.096780838987096 0.7374444069419024 0.034827099301386034 0.12440926104710637 2.4454654981193893 0.010445699975930802 0.016933235811346887 1.3941146279199554e-06 5.85570151588906 0.13553813173309415 VLAET(ph)PDSFEK ddPTM_PC-9_Lapatinib_30min_R1 3 VLAETPDSFEK 11 0 Q99567;J3KMX1 Q99567 NUP88 Nuclear pore complex protein Nup88 1 VLAET(0.999)PDS(0.001)FEK;VLAET(0.714)PDS(0.286)FEK;VLAET(0.773)PDS(0.227)FEK 104.94 0.006407899999999999 13733600.0 196677.0 171154.0 189414.0 163708.0 177022.0 192932.0 168781.0 166683.0 186383.0 151273.0 True False 193872.34991385508 170757.70342867065 173841.11207918383 175747.63243387846 166609.91399864247 184680.74810645828 177519.65432822434 174427.70068620786 165390.58383999948 177420.3364913974 1.0927290171341513 0.962447185060717 0.9798263012967111 0.9905720838400053 0.9390688648971247 1.0409220935922017 1.0005597883466517 0.9831325096977558 0.9321963147557145 1.0 17.436811859914222 -4.755282803539994 24.996280790617984 0.9818830312674629 1.0927291996450161 0.5573030799097284 0.029872270936264655 157.5324763225699 639535.1654485117 0.007433095386866843 0.06679428861396854 1.756779263268088e-05 4.755282803539994 0.11084616837755323 VLAGDKNFITAEELR ddPTM_PC-9_AZD4547_30min_R2 2 VLAGDKNFITAEELR 15 1 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ; 113.52 0.00026641 20301000.0 55692.0 50283.0 65245.0 90340.0 85531.0 71657.0 63317.0 80557.0 58977.0 69096.0 False True 73400.89753443768 66535.99641234211 64379.80866967434 69513.50873908658 73656.49702252726 67176.27646224803 68952.090338718 68108.76666570283 62094.403816068196 66676.9700711857 1.1008433265049893 0.997885721881287 0.9655479035856179 1.042541505183462 1.1046767263702906 1.0074884385197658 1.0341215304940121 1.0214736301452887 0.9312721281392201 1.0 16.02490092654636 -8.114120460601464 5.981581756588642 0.9664702702701308 1.0333506591987769 0.2914412496857739 0.04316454723938601 0.30969503524629405 13.987096405495627 0.030653386621341594 0.011310815565697204 7.689171355560648e-09 8.114120460601464 0.06688038892864612 VLAGDKNFITAEELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VLAGDKNFITAEELR 15 1 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ; 152.0 0.00019181 29290000.0 70144.0 58274.0 72368.0 79335.0 98241.0 77984.0 85554.0 81107.0 72663.0 64309.0 False True 82017.99379284956 64059.05760055071 74093.52757716838 74890.11715754039 78991.38127891945 73894.38175701395 77449.70576267877 78978.02718997003 73725.55891010954 75967.71263023611 1.0796427976193317 0.8432405739573945 0.9753291893598257 0.9858150859702621 1.039802023043667 0.9727077359389 1.0195081973792746 1.0396262366669675 0.9704854385830992 1.0 16.21309876224251 -5.786840688799044 3.2154713095051006 1.0077787308856194 0.9519709929518407 0.07919809610260375 0.05783998171156895 0.4535375874999794 9.659851845514083 0.015773686242728804 0.026730385316457002 1.6336511063024882e-06 5.786840688799044 -0.05580773793377869 VLAGDKNFITAEELR ddPTM_PC-9_Lapatinib_30min_R1 2 VLAGDKNFITAEELR 15 1 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 ; 112.84 0.00035786 20000600.0 83801.0 87195.0 78643.0 77437.0 93819.0 83915.0 87572.0 67133.0 85411.0 72284.0 False True 82605.98237277872 86993.10533474469 72177.27611075884 83131.9753022595 88300.75087525087 80326.15106541931 92106.04966691326 70252.24426106566 75791.11376229711 84778.19308762412 0.9743777186593222 1.0261259666720108 0.8513660586768892 0.9805820609592003 1.0415502814973414 0.9474860001132211 1.0864356305838612 0.8286593722097274 0.8939930305422027 1.0 16.371405597519434 -7.776444754919499 24.999696012232285 0.8959946955650255 0.9834954620769453 0.20291532384968392 0.07070083197929788 358.95907131858814 598034.7689685519 0.03762743788344439 0.01819025476620718 1.6732284683967463e-08 7.776444754919499 0.08750076651191974 VLAGETLS(ph)VNDPPDVLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLAGETLSVNDPPDVLDR 18 0 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3;K7EQR9;K7EKJ9 Q12906-7 ILF3 Interleukin enhancer-binding factor 3 1 VLAGET(0.065)LS(0.935)VNDPPDVLDR 85.176 0.014637 0.0 1335.5 1405.7 712.67 899.54 1198.8 1166.5 786.54 1266.9 2528.3 635.52 True False 1561.5737726726572 1545.2486060523427 729.6627556160258 849.1416901480284 963.9037456578051 1105.3266864941115 712.0332371435296 1233.6452173915081 2565.2716044263266 750.7347452264476 2.080060610757575 2.0583150252173854 0.9719315114367516 1.13108084519506 1.2839471621458767 1.4723265354672066 0.9484484921884837 1.643250462610996 3.4170146256552334 1.0 9.552159444592446 -8.018162236159153 24.83875892902317 2.3157158401509057 1.4052724691659908 0.17918737824417752 0.6570114503724079 969.1724473815001 1325436.8612132727 0.40944815852790833 0.16143520022409585 9.590423022917721e-09 8.018162236159153 -0.9104433709849149 VLANPGNSQVAR ddPTM_PC-9_Lapatinib_30min_R1 1 VLANPGNSQVAR 12 0 Q14974;J3QR48 Q14974 KPNB1 Importin subunit beta-1 0 95.48299999999999 0.021377 0.0 10398.0 10220.0 9446.2 11031.0 10592.0 9658.7 9062.7 9120.0 10267.0 8022.9 False True 10249.722613240338 10196.336217914924 8669.569899386473 11842.256538337258 9968.99938467322 9245.6199165294 9531.922261868336 9543.748494196876 9110.622343696994 9409.647575157729 1.0892780554609163 1.0836044747131786 0.9213490548014653 1.2585228557976842 1.0594445015127056 0.982568140058574 1.012994608537032 1.014251428437467 0.968221420720348 1.0 13.199924974556007 -6.642204646458931 5.535521514214147 0.9980789418949692 1.0854175573403972 0.24760303632860414 0.07659335983816747 0.3288382105022909 14.65763336605532 0.025645670869964363 0.025555035208981815 2.2792677917201767e-07 6.642204646458931 0.08733861544542809 VLAPILPDNFS(ph)TPTGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLAPILPDNFSTPTGSR 17 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 VLAPILPDNFS(0.442)T(0.442)PT(0.116)GSR 118.77 0.00010812 16232000.0 13459.0 15230.0 16441.0 15350.0 18862.0 12958.0 14729.0 11439.0 9721.8 8824.9 True False 15737.342872632931 16741.93374843648 16833.01579283971 14489.98926537145 15166.126501999932 12278.459668744714 13333.762491274496 11138.738370622346 9863.962933161363 10424.784512130042 1.5096084580282036 1.6059740831051181 1.6147111504562224 1.3899557586548892 1.4548143881873983 1.1778142420553421 1.2790444230055436 1.0684861982194034 0.9462030530879445 1.0 13.34772994197292 -7.011467987563451 0.643117494648785 0.9610123474086281 1.5971589597060978 0.8964008406016087 0.0756616741757195 0.22160149839584453 0.19292861145912182 0.062270539193337075 0.05305303343418976 9.739395730925135e-08 7.011467987563451 0.6361466122974697 VLAPILPDNFS(ph)TPTGSR ddPTM_PC-9_Lapatinib_30min_R1 1 VLAPILPDNFSTPTGSR 17 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 VLAPILPDNFS(0.861)T(0.115)PT(0.024)GSR 156.29 2.7266999999999998e-05 15396000.0 58855.0 57176.0 66388.0 51634.0 56015.0 48374.0 36458.0 44296.0 53263.0 31027.0 True False 58015.716907314825 57043.612484882964 60929.834905090815 55431.33660597465 52720.307829727215 46305.15678530169 38345.616849635975 46354.153870498296 47263.96005574491 36389.97560912123 1.5942774331723666 1.5675639109410353 1.674357673650614 1.5232584160369882 1.4487590867335658 1.2724701242639798 1.0537412077853814 1.273816568837697 1.298818129570224 1.0 15.151253463743274 -6.630030874122628 1.754459185545201 1.1754014914348576 1.6001091000332477 0.8243095468732975 0.0911023705689962 0.1473177980189866 0.931242351884084 0.03659865525695333 0.03687713484044741 2.3440621693265387e-07 6.630030874122628 0.4247076085983901 VLAPILPDNFST(ph)PTGSR ddPTM_PC-9_AZD4547_30min_R2 3 VLAPILPDNFSTPTGSR 17 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 VLAPILPDNFST(0.989)PT(0.01)GSR;VLAPILPDNFS(0.074)T(0.882)PT(0.044)GSR;VLAPILPDNFS(0.193)T(0.715)PT(0.086)GS(0.005)R 245.04 7.5295e-47 51796000.0 117977.8 122584.3 171956.9 212330.4 201582.8 173718.1 130434.6 192143.8 144095.6 177241.8 True False 155492.28630931533 162207.27770835988 169676.6391513573 163380.90675197836 173596.50779241027 162855.47974512549 142043.02671469832 162452.39073527374 151712.19923900234 171036.6185302053 0.9091169344058049 0.9483774825664824 0.9920486069560137 0.9552393408849174 1.0149669075792263 0.9521673261820537 0.8304831324153741 0.9498105851910562 0.8870158948576836 1.0 17.38394571016908 -7.019552960961435 24.80256505991124 0.9095992753149174 0.9661023785482246 0.17017080206907442 0.048269121538268706 1014.9163864724661 1287399.6136712355 0.017518573727836554 0.013776332492653092 9.55976109377692e-08 7.019552960961435 0.056503103233307206 VLAPILPDNFST(ph)PTGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VLAPILPDNFSTPTGSR 17 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 VLAPILPDNFS(0.077)T(0.897)PT(0.026)GSR;VLAPILPDNFS(0.081)T(0.862)PT(0.057)GSR;VLAPILPDNFS(0.076)T(0.892)PT(0.031)GSR 245.04 7.5295e-47 26040400.0 60236.0 50628.0 57709.0 60205.0 65896.0 53235.0 51648.0 44376.0 40798.0 34969.0 True False 70432.76508476984 55654.013251204364 59085.00142260127 56831.90903724356 52984.15183839396 50443.26288513849 46755.52754086127 43211.177020258525 41394.593567767 41308.602885548295 1.7050386642200033 1.347274159946832 1.4303316330088716 1.3757886993831507 1.2826420681714783 1.2211321458849418 1.1318593289248853 1.046057576432241 1.002081665227385 1.0 15.33415464661407 -5.729519199910649 0.3239643908454045 0.945365781920396 1.8272067774014713 0.8890749824186973 0.07034451347404544 1.2093183132328842 0.1635619723088464 0.07997217159394925 0.4005453982898258 1.864149763435922e-06 5.729519199910649 0.8818409954810753 VLAPILPDNFST(ph)PTGSR ddPTM_PC-9_Lapatinib_30min_R1 3 VLAPILPDNFSTPTGSR 17 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 VLAPILPDNFS(0.211)T(0.694)PT(0.094)GS(0.001)R;VLAPILPDNFS(0.132)T(0.779)PT(0.066)GS(0.023)R;VLAPILPDNFS(0.121)T(0.812)PT(0.065)GS(0.002)R 145.94 0.00023348 19444200.0 62606.5 52108.0 70889.4 52591.8 58021.7 55126.4 42906.1 41190.3 56692.0 36291.1 True False 61713.71982937399 51987.34712750601 65061.14717299739 56459.57641310176 54608.97768105122 52768.772377914895 45127.567916840366 43104.15171058305 50306.74996677411 42563.96828014889 1.4499052208474703 1.2213933340362915 1.528549846310754 1.3264641125915306 1.2829860534061135 1.239752177959529 1.0602293381063133 1.0126910965368352 1.1819093002716177 1.0 15.37734504052034 -6.9127184416236656 1.4145345065327108 1.0585161444285662 1.379099196994589 0.7166691468828855 0.0892323522063018 0.22117310474403226 0.9122590419228014 0.04303558528920934 0.0341298977245417 1.222592024514911e-07 6.9127184416236656 0.3205830525660227 VLATVTKPVGGDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLATVTKPVGGDK 13 1 Q02878;F8VZ45;U3KQR5;F8VZA3;F8VWR1;F8VU16 Q02878 RPL6 60S ribosomal protein L6 0 83.617 0.037727 0.0 37609.0 46931.0 41301.0 57814.0 50244.0 41057.0 49735.0 43795.0 42938.0 33701.0 False True 43975.4608883908 51589.99952382619 42285.77247491475 54574.86901551692 40399.0488795719 38903.89864328227 45023.74074978189 42645.42765463814 43565.88701928473 39810.72452303081 1.1046134280462707 1.2958819549737404 1.062170382014829 1.3708584726697184 1.0147780369131625 0.9772215680419497 1.1309450227095292 1.0712045099799032 1.0943253995310116 1.0 15.280869507102098 -6.305127687374597 24.997483293115256 1.0522397094031837 1.2041877379156058 0.42163905213449515 0.0918457723828167 451.8014766692247 258509.5768515145 0.02696845087017682 0.030579596340415738 4.953045443881692e-07 6.305127687374597 0.15194802851242217 VLAVNQENEHLMEDYEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VLAVNQENEHLMEDYEK 17 0 O43707;O43707-2;K7EJH8 O43707 ACTN4 Alpha-actinin-4 0 ;; 105.53 0.00048612 24038000.0 67696.0 75682.0 73606.0 91497.0 104173.0 90690.0 99315.0 93272.0 83333.0 64664.0 False True 79155.59574305355 83195.20879508663 75361.04619230932 86370.7197272763 83761.04846213768 85934.05674937934 89907.1642216665 90823.70882985297 84551.587474453 76387.07132005756 1.0362433638985324 1.089126829414671 0.986568078733517 1.1306981434775503 1.0965343613081273 1.1249816921154163 1.176994518417397 1.188993206053243 1.106883481894293 1.0 16.221040859161164 -5.78690706201698 24.770868900669686 1.127615033995978 1.0424941662572718 0.3057950131471979 0.05407852298950751 215.52845931688583 209630.67819630043 0.01489635708670144 0.022104687580565312 1.633401454510627e-06 5.78690706201698 -0.08512086773870631 VLAVNQENEHLMEDYEK ddPTM_PC-9_Lapatinib_30min_R1 4 VLAVNQENEHLMEDYEK 17 0 O43707;O43707-2;K7EJH8 O43707 ACTN4 Alpha-actinin-4 0 ;;; 151.73 2.7868e-05 47813500.0 362728.0 316571.0 350108.0 331998.0 346908.0 332683.0 341591.0 328956.0 348652.0 322813.0 False True 357555.4322038311 315837.9992995647 321323.4716959628 356414.24043286237 326503.55348736985 318454.9236119511 359276.91056240007 344240.49667292007 309383.14029167645 378610.79692871514 0.9443878386573102 0.8342023044816408 0.8486907248882858 0.9413736832760426 0.862372537011521 0.8411142159580564 0.9489346671485567 0.9092199680130456 0.8171535064540886 1.0 18.530356027721986 -11.651445571608381 2.5061161679135244 1.2453313506203805 0.8831840129496422 0.35582128318341577 0.04720696354408723 11849380.05404526 4453648.299512935 16463524.742014073 0.011912605020208957 2.2312818275931696e-12 11.651445571608381 -0.36214733767073826 VLCSS(ph)LNLSPARY(ph)VT(ph)VK ddPTM_PC-9_AZD4547_30min_R2 1 VLCSSLNLSPARYVTVK 17 1 Q86TJ2-3;Q86TJ2-2;Q86TJ2 Q86TJ2-3 TADA2B Transcriptional adapter 2-beta 3 VLCS(0.105)S(0.892)LNLS(0.004)PARY(0.999)VT(1)VK 57.986000000000004 0.040614 5634800.0 8927.5 10811.0 16675.0 20365.0 20454.0 16907.0 15619.0 21465.0 14951.0 21562.0 True False 11766.259296464366 14305.444329372353 16453.87860474856 15670.163886113532 17614.315161739836 15849.802617291092 17009.060741987723 18148.07746662998 15741.27933692855 20807.12094296201 0.565491945220047 0.6875263698705589 0.7907811296840694 0.7531154324074784 0.8465522553564943 0.7617489541556336 0.8174634438187866 0.8722051222934113 0.7565332743573552 1.0 14.344789734403458 -2.566051513635164 0.14442461649078409 0.9880313164617819 1.3553063212700894e-32 0.7029296830240601 0.059396527806458405 32.70141333257382 0.41359885509674793 0.25638066970202883 6.382642159226828 0.0027161170787848308 2.566051513635164 -0.9880313164617819 VLDDVSIRS(ph)PETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLDDVSIRSPETK 13 1 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;F5GXF5;Q12830-2 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 VLDDVS(0.05)IRS(0.947)PET(0.003)K 53.008 0.042132 7097700.0 42633.0 44115.0 38901.0 53881.0 58972.0 47215.0 47295.0 49653.0 42368.0 34449.0 True False 49849.924859867744 48494.44565412184 39828.547372864035 50862.2222545589 47416.85993404412 44738.96228274282 42814.87521385209 48349.66136170219 42987.55184761879 40694.33100186607 1.224984503556081 1.1916757066702506 0.9787247115829885 1.2498601402791603 1.1651957107212252 1.0993905337991987 1.0521090815300238 1.1881178574845002 1.0563523416971166 1.0 15.312540210769766 -14.522878745205036 0.0720842371133745 0.532822811617274 1.294056213677115 0.28820744706187706 0.07692985715576169 427.63567896194667 2.2037521830864897 32.65742881464674 3.8095458194714267 3.0000000005201656e-15 14.522878745205036 0.761233402059841 VLDDVSIRS(ph)PETK ddPTM_PC-9_Lapatinib_30min_R1 2 VLDDVSIRSPETK 13 1 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;F5GXF5;Q12830-2 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 VLDDVS(0.012)IRS(0.986)PET(0.002)K;VLDDVSIRS(0.999)PET(0.001)K 73.758 0.0096934 67690000.0 531030.0 456340.0 494180.0 478730.0 493910.0 516010.0 451320.0 457390.0 533500.0 413750.0 True False 523457.41482102463 455283.37276744534 453550.4279899642 513937.4011964643 464859.18486442097 493941.45517806086 474687.1412742795 478642.0091842873 473411.61199594283 485266.1362127792 1.078701718002221 0.9382137734165175 0.9346426509990214 1.0590835890743329 0.9579468876447413 1.0178774456280577 0.9781996019317099 0.9863494966284081 0.9755710870135014 1.0 18.88841666109466 -4.743263247144526 24.897794203652982 0.9836797929989578 1.0787020340173823 0.39953345277864194 0.035154598762293036 1175.0325809235533 1609478.7950913482 0.008623121206419438 0.27526195101327094 1.8060790412363802e-05 4.743263247144526 0.09502224101842449 VLDEEGS(ph)ER ddPTM_PC-9_AZD4547_30min_R2 2 VLDEEGSER 9 0 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 VLDEEGS(1)ER;VLDEEGS(1)ER 104.79 0.0026791999999999996 30107000.0 79150.0 127180.0 141530.0 68622.0 104734.0 172513.0 150399.0 223160.0 160949.0 98309.0 True False 104318.05357772675 168288.4478595481 139653.2197259408 52802.25809933139 90193.49194043485 161725.7348386311 163784.21963853104 188675.74970664564 169456.43555610406 94867.2318329306 1.0996215612303295 1.7739365280091508 1.4720912271571518 0.5565911124330131 0.9507338856400215 1.7047586581154186 1.7264572442354933 1.9888400458328959 1.7862483418355823 1.0 16.53362223038122 -6.778996875882647 24.562715207385676 1.7083883859610225 1.1867523723262234 0.264533449437262 0.38385835859098655 267.7184844879107 374531.9569361512 0.1426183259756169 0.12607451529045258 1.6634246162487029e-07 6.778996875882647 -0.5216360136347991 VLDEEGS(ph)ER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VLDEEGSER 9 0 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 VLDEEGS(1)ER;VLDEEGS(1)ER 88.596 0.0099959 27573500.0 71139.0 188875.0 144690.0 62681.0 76605.0 58922.0 86435.0 50285.0 57896.0 66454.0 True False 83181.42764070405 207625.26176861112 148139.95833988077 59169.186784543854 61594.80016359369 55832.02659374718 78247.25106479148 48965.07203136157 58742.61947152896 78501.58415042527 1.0596146376015956 2.644854419380355 1.8870951451885858 0.7537323918350928 0.7846313017781311 0.7112216549256059 0.9967601534620443 0.6237462920179339 0.7482985229822362 1.0 16.26043414722126 -5.751492951223884 7.863007427045732 0.7896114217257671 1.946037823514092 0.6259859135399368 0.37425666931491086 0.07727533346244918 30.042561675111287 0.09727597450266719 0.16030269138878409 1.7721768080522294e-06 5.751492951223884 1.156426401788325 VLDEEGS(ph)ER ddPTM_PC-9_Lapatinib_30min_R1 1 VLDEEGSER 9 0 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 VLDEEGS(1)ER 106.4 0.0025719000000000002 24192000.0 46143.0 84176.0 47823.0 45763.0 62888.0 62180.0 65683.0 80910.0 70818.0 67016.0 True False 45484.99235841017 83981.09564375794 43891.17754211847 49128.56368089275 59189.0514825651 59520.706348659565 69083.74435061266 84669.37397647703 62841.73109339962 78599.62630679291 0.578692221523694 1.0684668565211735 0.558414582924362 0.6250483111603147 0.7530449477143345 0.7572644953340641 0.8789322239391124 1.0772236199443552 0.7995169194330962 1.0 16.26223483291605 -7.32779870084751 2.882058540261737 0.9571171197624759 0.7254827773964271 0.34420405677059096 0.14848621525030808 0.32477672956920123 5.307721213610012 0.06826530572410645 0.04404944653902768 4.701119589685459e-08 7.32779870084751 -0.23163434236604885 VLDETAR ddPTM_PC-9_Lapatinib_30min_R1 1 VLDETAR 7 0 Q03252 Q03252 LMNB2 Lamin-B2 0 97.602 0.019324 0.0 20997.0 17919.0 19926.0 15368.0 18411.0 18114.0 19102.0 16426.0 18587.0 14797.0 False True 20697.578929621795 17877.50965644007 18287.761196584328 16498.213986145143 17328.10117741869 17339.306445796385 20091.008093196182 17189.211926061173 16493.53633021291 17354.64173423685 1.1926249614701105 1.0301284192557958 1.0537677168239457 0.9506513726294812 0.9984706940526579 0.999116358108954 1.1576734570994391 0.9904676909665429 0.9503818392099003 1.0 14.083033962314692 -4.51732682741329 1.9774634880368727 1.0139615506185788 1.3780586592659496 0.474661999222184 0.05628500141827354 1.88671161514952 4.137191952837457 0.015640955446466438 1.607752831672242 3.0385974747991755e-05 4.51732682741329 0.36409710864737077 VLDPFTIKPLDR ddPTM_PC-9_AZD4547_30min_R2 2 VLDPFTIKPLDR 12 1 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 ; 129.74 0.00021573 15652100.0 116499.0 115834.0 126629.0 166399.0 134969.0 135409.0 118448.0 154782.0 114049.0 128567.0 False True 153543.25867026646 153275.0752426711 124949.81672208136 128038.28138892264 116230.88408452416 126941.85382414224 128989.6425358195 130863.99843652092 120077.39730435172 124065.9084627494 1.2375942801109427 1.2354326594778589 1.0071245055977434 1.032018247199358 0.9368478861332186 1.0231807867046436 1.0396864387169538 1.0547941820440756 0.9678516749055586 1.0 16.92074721239826 -5.26087059506101 24.47805476257939 1.0096799479548815 1.2365135010520119 0.8860169782488075 0.03282322005302871 10.831538517761956 466104.16479331115 0.008713812457938216 0.020394674633934635 5.484403570925347e-06 5.26087059506101 0.22683355309713038 VLDPFTIKPLDR ddPTM_PC-9_Lapatinib_30min_R1 1 VLDPFTIKPLDR 12 1 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 89.43 0.009716299999999999 14764000.0 129900.0 147460.0 171210.0 167980.0 139120.0 154460.0 171580.0 143490.0 152770.0 145240.0 False True 128047.60217925718 147118.56542991544 157133.77468971227 180333.80956485344 130937.23512044367 147854.10586384605 180463.57285261244 150157.069235999 135563.4338605814 170344.54047986525 0.7516977169831424 0.8636529531001017 0.9224467907633677 1.0586415570281744 0.7686611778199048 0.8679709102935556 1.0594033266005567 0.8814903536855505 0.7958190704480196 1.0 17.378096184425566 -4.833693614019509 2.6508888274968263 0.9172393547152246 0.729158035254776 0.2291901385420828 0.0936480231500927 0.6501823454780432 6.637119548007063 0.02465163560182529 0.2616885948271087 1.466582120129638e-05 4.833693614019509 -0.1880813194604486 VLDSVEAGDT(ph)TPPTK ddPTM_PC-9_Lapatinib_30min_R1 2 VLDSVEAGDTTPPTK 15 0 Q8IZ21-3 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 VLDS(0.001)VEAGDT(0.499)T(0.499)PPTK;VLDSVEAGDT(0.589)T(0.409)PPT(0.002)K 163.99 0.00063808 17373500.0 157588.0 142675.0 153701.0 132675.0 146202.0 131315.0 118505.0 117420.0 146928.0 92672.0 True False 155340.7662218998 142344.6448034258 141064.2970830178 142432.36209082534 137602.68580419116 125698.96356021613 124640.60905058165 122875.7618627848 130379.4214195687 108690.2317223217 1.429206321123313 1.3096360413241486 1.2978562548601822 1.3104430806137846 1.2660078428734431 1.1564881366832283 1.1467507896110616 1.130513385753964 1.1995504964296868 1.0 16.729862761821195 -1.5228787476117789 0.11574631217636268 0.9160282795503811 2.450811618408614 0.8863297580431417 0.03905264956123808 32.22084359148597 0.2590616357100416 0.3182939341742326 7.935875775019501 0.02999999983894974 1.5228787476117789 1.5347833388582328 VLDSVEAGDTT(ph)PPTK ddPTM_PC-9_AZD4547_30min_R2 1 VLDSVEAGDTTPPTK 15 0 Q8IZ21-3 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 VLDSVEAGDT(0.038)T(0.962)PPTK 197.06 2.3133000000000003e-09 10057000.0 34399.0 39717.0 47319.0 70082.0 63858.0 52182.0 46790.0 56835.0 46485.0 60184.0 True False 45337.166456351486 52554.74354173362 46691.519142314675 53925.67765610652 54992.41896931559 48919.05129091408 50954.219355759386 48052.456688372455 48942.10219899161 58076.97647858387 0.7806392344317331 0.9049152818951138 0.8039591930122666 0.928520748251966 0.9468884625836932 0.8423140159328575 0.8773566126423432 0.8273925331855387 0.8427109186208965 1.0 15.825678727289178 -12.107579384934843 2.1553796534461767 3.466060717130516 0.8645717000514531 0.3999908761230673 0.05072545200625346 2425447.448973741 156887.07840816813 29495298.940289278 0.013527672260622904 7.805857433854182e-13 12.107579384934843 -2.601489017079063 VLDTADPRT(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 VLDTADPRTPR 11 1 Q96BT3;H3BMP6;H3BQS6;H3BN05;H3BTS2;H3BQJ0;I3L4F8;H3BUW2;H3BTR4;Q96BT3-3;Q96BT3-2;H3BQ71 Q96BT3 CENPT Centromere protein T 1 VLDTADPRT(1)PR;VLDTADPRT(1)PR 80.318 0.01175 7024200.0 42586.0 31259.0 53970.0 100232.0 89163.0 57404.0 45793.0 68161.0 45575.0 63783.0 True False 56127.46215617268 41362.86044693833 53254.32253662844 77125.06096896307 76784.25651541055 53814.518805404754 49868.488287204294 57628.28363396064 47984.001456793456 61549.976584034266 0.9119006256572947 0.6720207340853421 0.8652208415371245 1.253047771085081 1.2475107348022612 0.8743223278392596 0.8102113283360681 0.9362844119896725 0.7795941464133757 1.0 15.909470687402901 -10.687743336762702 17.541759991980673 1.0000000000000608 0.9326163798500511 0.013965918244711384 0.17791193732829683 0.0 0.0 0.19158118400687466 0.04646526220830807 2.052374751269012e-11 10.687743336762702 -0.06738362015000976 VLDTADPRT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 VLDTADPRTPR 11 1 Q96BT3;H3BMP6;H3BQS6;H3BN05;H3BTS2;H3BQJ0;I3L4F8;H3BUW2;H3BTR4;Q96BT3-3;Q96BT3-2;H3BQ71 Q96BT3 CENPT Centromere protein T 1 VLDTADPRT(1)PR 60.628 0.045245 3614600.0 37636.0 22947.0 34384.0 27122.0 25832.0 28054.0 17536.0 18466.0 27288.0 21067.0 True False 37099.303738402894 22893.86763135949 31557.080246078287 29116.64235633971 24312.612547666027 26854.195817068106 18443.928275693026 19323.997773447314 24214.538084620974 24708.40287998702 1.5014853011180294 0.9265620178916039 1.2771800912975426 1.1784105390285349 0.9839815493440262 1.0868446636354268 0.7464637987845014 0.7820820255889184 0.9800122736477613 1.0 14.592714139241249 -6.577813919382349 1.244491952761319 0.8700815817276277 1.2151220699233893 0.4552714782970274 0.15899400615523956 0.40536396370100786 1.316449774424093 0.07015768155525132 0.07510282351706235 2.643541183424264e-07 6.577813919382349 0.3450404881957616 VLDTSSLTQS(ph)APAS(ph)PTNK ddPTM_PC-9_AZD4547_30min_R2 2 VLDTSSLTQSAPASPTNK 18 0 Q8N122-3;Q8N122;I3L436 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 2 VLDT(0.003)S(0.004)S(0.008)LT(0.084)QS(0.903)APAS(0.552)PT(0.447)NK;VLDTSS(0.001)LT(0.086)QS(0.912)APAS(0.896)PT(0.105)NK 113.14 0.0019637 14842100.0 73440.0 66369.0 94250.0 121540.0 101613.0 97878.0 99671.0 107301.0 90703.0 101588.0 True False 96792.39235310494 87821.48133346712 93000.18341814405 93520.83077428129 87505.78891805364 91757.67318715439 108541.52591168802 90720.09598168456 95497.37540615552 98031.43504098068 0.9873607615010657 0.895850206586842 0.9486771603339951 0.9539881848632146 0.8926298883768565 0.9360025500881056 1.1072114354575524 0.9254184226086284 0.974150540244914 1.0 16.580956821692972 -7.053697357544349 24.999920692453124 0.9992124186531679 0.9331330150975716 0.2985491973105052 0.04938195788969927 411.6790092643284 191664.41973409906 0.018450215614284258 0.014291561743508012 8.836954979517901e-08 7.053697357544349 -0.06607940355559627 VLDTSSLTQS(ph)APAS(ph)PTNK ddPTM_PC-9_Lapatinib_30min_R1 2 VLDTSSLTQSAPASPTNK 18 0 Q8N122-3;Q8N122;I3L436 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 2 VLDTSS(0.001)LT(0.131)QS(0.872)APAS(0.925)PT(0.071)NK;VLDTSS(0.001)LT(0.08)QS(0.918)APAS(0.999)PT(0.001)NK 157.47 0.00014325 11081500.0 79936.0 93372.0 89047.0 83822.0 80134.0 82260.0 80455.0 71725.0 80755.0 67842.0 True False 78796.09798153293 93155.80287075855 81725.89939136039 89986.54950199515 75420.67566950561 78741.93155742576 84620.56623066164 75057.60534498571 71659.52151215063 79568.39930621732 0.9902938687793353 1.1707638168294725 1.0271150369236406 1.1309332635395088 0.9478722247415172 0.9896131158098215 1.0634946406927348 0.9433092282795346 0.9006027787032697 1.0 16.279907955844664 -6.267992466152802 24.980460283390507 0.9765546457404872 1.0825140587213635 0.414830755856444 0.061385222240762136 518.7751220009601 1977576.8782154555 0.0185722922816719 0.021550050525736476 5.395199816620109e-07 6.267992466152802 0.1059594129808763 VLDTSSLTQS(ph)APASPT(ph)NK ddPTM_PC-9_AZD4547_30min_R2 1 VLDTSSLTQSAPASPTNK 18 0 Q8N122-3;Q8N122;I3L436 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 2 VLDTSSLT(0.019)QS(0.981)APAS(0.019)PT(0.981)NK 166.36 2.6753000000000004e-23 0.0 24417.0 29318.0 28896.0 39392.0 31024.0 31584.0 34268.0 39852.0 29785.0 38424.0 True False 32181.098094849665 38794.47015526212 28512.820159688996 30310.783000333155 26716.85311322071 29609.047487107233 37317.78561408766 33693.7891078564 31359.37429271733 37078.78745535536 0.8679112857613602 1.0462712730822852 0.7689793037061904 0.8174696391253028 0.7205427940541228 0.7985441142798412 1.0064456843153262 0.9087079546068041 0.8457497249734911 1.0 15.178306445499178 -9.800093644483761 8.99973674409139 0.9999999986341324 0.8649654916655131 0.15233702815560435 0.09587422854480943 0.0 0.0 0.09922203191676005 0.024064877528306383 1.5845514876708186e-10 9.800093644483761 -0.1350345069686193 VLDTSSLTQS(ph)APASPTNK ddPTM_PC-9_Lapatinib_30min_R1 1 VLDTSSLTQSAPASPTNK 18 0 Q8N122-3;Q8N122;I3L436 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 1 VLDTSSLT(0.045)QS(0.705)APAS(0.242)PT(0.008)NK 156.06 1.4632e-05 37846000.0 31477.0 25378.0 29160.0 29259.0 30202.0 29301.0 25829.0 30660.0 34015.0 27090.0 True False 31028.13220782517 25319.238800219675 26762.57736085513 31410.804465162742 28425.57773941661 28047.86453396708 27166.29923773237 32084.575529832888 30183.872506170574 31772.470404843993 0.9765728573342115 0.796892356105855 0.8423196880773534 0.9886170028621347 0.894660609553448 0.8827725441736799 0.8550263448696338 1.0098231305596341 0.9500008064078258 1.0 14.95548964782737 -7.764767749640764 24.999950798486744 0.9849339909573316 0.8890710136508094 0.37799082365115466 0.05616521624065185 94.91022626962837 712861.946813299 0.0295167157428232 0.015099337442789521 1.718827329394949e-08 7.764767749640764 -0.09586297730652216 VLDTSSLTQSAPAS(ph)PTNK ddPTM_PC-9_AZD4547_30min_R2 5 VLDTSSLTQSAPASPTNK 18 0 Q8N122-3;Q8N122;I3L436 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 1 VLDTSSLT(0.011)QS(0.109)APAS(0.865)PT(0.015)NK;VLDTSSLTQS(0.008)APAS(0.947)PT(0.045)NK;VLDTSSLTQS(0.003)APAS(0.995)PT(0.001)NK;VLDTSSLTQS(0.001)APAS(0.814)PT(0.186)NK;VLDTSSLTQSAPAS(0.992)PT(0.008)NK 197.41 1.2612e-14 129620000.0 202062.0 183007.0 237971.0 274761.0 280949.0 248629.0 222002.0 273190.0 228074.0 240080.0 True False 266313.5128493062 242160.4338530615 234815.34905251107 211419.09646513336 241944.08088274347 233082.1893259873 241759.74792514023 230974.76278167416 240129.5260177007 231674.87227466496 1.1495140160628858 1.0452598137875102 1.0135555347328427 0.9125680933341915 1.0443259491512904 1.0060745347024682 1.0435302955018748 0.9969780516716514 1.0364936156434446 1.0 17.821742050747417 -4.776460490725237 2.394974133417696 1.0062717950382478 1.1840974960194128 0.5937989508101693 0.03565864396993921 0.4057838392612634 2.8289161410338686 0.00947081612647304 0.15312674456558403 1.6731678433549014e-05 4.776460490725237 0.177825700981165 VLDTSSLTQSAPAS(ph)PTNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 VLDTSSLTQSAPASPTNK 18 0 Q8N122-3;Q8N122;I3L436 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 1 VLDTSSLTQSAPAS(0.997)PT(0.002)NK;VLDTSSLTQS(0.006)APAS(0.953)PT(0.04)NK;VLDTSSLTQS(0.003)APAS(0.997)PTNK;VLDTSSLT(0.013)QS(0.323)APAS(0.646)PT(0.018)NK;VLDTSSLTQS(0.003)APAS(0.991)PT(0.006)NK 227.88 4.5558999999999997e-35 99122500.0 134246.0 123747.0 136908.0 160329.0 192279.0 163467.0 185091.0 180544.0 167155.0 151557.0 True False 156971.196320639 136031.78434456795 140172.40594648157 151346.28592363137 154603.3102363506 154894.50275279314 167557.8405372049 175804.91130218035 169599.32564880833 179033.0843754479 0.8767720048404951 0.7598136669493862 0.782941356540157 0.8453537314156141 0.8635460355033265 0.8651725087189244 0.9359043392550931 0.9819688462357169 0.947307176438651 1.0 17.44986668904327 -7.107515856008208 0.8350683183049105 0.9881703419515762 0.8045041893687901 0.8118026951491688 0.0329456044988095 0.2534886715744284 0.35839980786066894 0.02498393375355448 0.016897792286289348 7.806999364126891e-08 7.107515856008208 -0.18366615258278607 VLDTSSLTQSAPAS(ph)PTNK ddPTM_PC-9_Lapatinib_30min_R1 4 VLDTSSLTQSAPASPTNK 18 0 Q8N122-3;Q8N122;I3L436 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 1 VLDTSSLTQSAPAS(0.773)PT(0.227)NK;VLDTSSLT(0.008)QS(0.099)APAS(0.852)PT(0.042)NK;VLDTSSLTQSAPAS(0.972)PT(0.028)NK;VLDTSSLTQSAPAS(0.77)PT(0.23)NK 310.98 1.3600999999999995e-138 70142000.0 180260.0 166521.0 165448.0 163062.0 190822.0 198391.0 176830.0 184730.0 231186.0 169088.0 True False 177689.45934436496 166135.43085551955 151845.5040877488 175054.1234388861 179598.2251304863 189906.2794020088 185985.39216416515 193313.23019002058 205147.3981834941 198314.63550440196 0.8959977103677798 0.8377366119901517 0.7656797679179775 0.8827090496555936 0.9056226469301596 0.9576009300523535 0.9378298867913702 0.9747804527807008 1.0344541524215467 1.0 17.597431625984818 -6.752952032001355 0.9072691258923714 1.000022236934215 0.8326113905663065 0.7574041559957227 0.03718011650259664 0.29276516540575465 0.5225035769115791 0.024079403597785112 0.0224871948733547 1.7662328910400394e-07 6.752952032001355 -0.1674108463679086 VLEDDPEAT(ph)YTTSGGK ddPTM_PC-9_AZD4547_30min_R2 2 VLEDDPEATYTTSGGK 16 0 P29317 P29317 EPHA2 Ephrin type-A receptor 2 1 VLEDDPEAT(0.405)Y(0.381)T(0.169)T(0.044)S(0.001)GGK;VLEDDPEAT(0.777)Y(0.137)T(0.074)T(0.011)S(0.001)GGK 166.7 8.5681e-06 6266600.0 21278.0 46838.0 33992.0 29056.0 28893.0 28142.0 33298.0 32676.0 25626.0 27089.0 True False 28043.961390105713 61977.46753298885 33541.243870021775 22357.588110725006 24881.705679483162 26382.276291228845 36261.457493226655 27626.675019781098 26980.538043484128 26140.622355249885 1.0728115424716955 2.370925477240666 1.2831080841992886 0.8552814009890961 0.9518406004777507 1.009244383423428 1.3871688669242481 1.0568484041556403 1.0321306691485699 1.0 14.674005868737286 -5.5102083557803665 24.36374478464501 1.0546551264126973 1.748155682665179 0.41752087027099405 0.3178646727078213 347.11971929282004 667470.6853705256 0.07895325399310334 0.15233189456780677 3.0888131974984927e-06 5.5102083557803665 0.6935005562524816 VLEDDPEAT(ph)YTTSGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLEDDPEATYTTSGGK 16 0 P29317 P29317 EPHA2 Ephrin type-A receptor 2 1 VLEDDPEAT(0.904)Y(0.073)T(0.018)T(0.004)S(0.001)GGK 133.32 2.6535999999999998e-05 0.0 6500.1 7214.1 4984.3 5416.7 9504.5 6026.4 6413.9 6961.8 5715.1 4668.4 True False 7600.438547172993 7930.268171674046 5103.144615063013 5113.219860178341 7642.161453624133 5710.364975129119 5806.328959385258 6779.06012663683 5798.6725255930505 5514.743964965935 1.3782033391680661 1.4380120313931983 0.9253638332953024 0.9271907984598384 1.3857690406251415 1.0354723648832882 1.0528737138608253 1.2292610807868583 1.0514853567873426 1.0 12.429078191503498 -5.246082060123148 24.833879794040833 1.0876005557518722 1.4081077512318654 0.4996382966793702 0.13255724402794644 634.2609979280664 1025640.7539452957 0.03424332405867639 0.08987821034918898 5.6743737774976694e-06 5.246082060123148 0.3205071954799932 VLEDDPEATY(ph)TTSGGK ddPTM_PC-9_Lapatinib_30min_R1 1 VLEDDPEATYTTSGGK 16 0 P29317 P29317 EPHA2 Ephrin type-A receptor 2 1 VLEDDPEAT(0.153)Y(0.514)T(0.24)T(0.071)S(0.021)GGK 113.95 0.00029205 2502500.0 21649.0 41836.0 15893.0 11251.0 18651.0 11514.0 12175.0 12152.0 17630.0 8886.5 True False 21340.281290059615 41739.13131239617 14586.338888754124 12078.43607223575 17553.98484927683 11021.573060444938 12805.361927267479 12716.626283057065 15644.323747869668 10422.519684483055 2.0475165253782937 4.004706402669306 1.399502167452859 1.158878700917016 1.6842361905452699 1.0574768284538476 1.2286243936129932 1.2201105556067648 1.5010116767791557 1.0 13.347416476443103 -5.34924810223251 7.878720507600103 1.2837718221085619 3.0203067278731637 0.6809019656736132 0.4780567857542423 0.13415392717945737 10.710923744903127 0.11366402568904656 0.23791454869058065 4.474576091292421e-06 5.34924810223251 1.7365349057646018 VLEDSDLK ddPTM_PC-9_AZD4547_30min_R2 1 VLEDSDLK 8 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 93.374 0.033509 3613200.0 17743.0 20695.0 25501.0 29030.0 26611.0 24139.0 22959.0 24905.0 21721.0 24183.0 False True 23384.90492267344 27384.254037217732 25162.840077942594 22337.582009029033 22916.521989295914 22629.584514035007 25002.306522523602 21056.504509965966 22869.127715699622 23336.360530732316 1.0020802040608343 1.1734586462681116 1.0782675406820585 0.9572007588592075 0.9820092537187406 0.9697135285612966 1.0713884236403253 0.9023045595407243 0.9799783340501026 1.0 14.510291959717243 -5.6950786973531144 5.875630122537866 0.9798003735828825 1.0958980433891645 0.42656797984726147 0.05511708999810284 0.1720219254013234 10.94928475601529 0.014537008383040105 0.025256035984231113 2.018000653992794e-06 5.6950786973531144 0.116097669806282 VLEDSDLK ddPTM_PC-9_Lapatinib_30min_R1 1 VLEDSDLK 8 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 101.54 0.020983 11030000.0 53568.0 48846.0 45560.0 41063.0 47611.0 42238.0 50550.0 43734.0 42385.0 47625.0 False True 52804.11049683189 48732.90008808927 41814.232666685864 44082.9100021524 44810.61458682747 40431.57920158704 53167.231656950426 45766.04129881645 37611.15496616312 55856.91779367642 0.9453459407101382 0.8724595271815435 0.7485954169748276 0.7892112874001623 0.8022392992099627 0.7238419303931646 0.951846857238684 0.8193441941760282 0.6733481984288989 1.0 15.769448346893402 -10.758793510369737 4.681046253522743 1.000049214212169 0.8143010725794452 0.2999641256981527 0.08523040846541614 4.414184004717071e-05 7.205269020573951e-06 0.08321484614778994 0.02017722309988881 1.7426352297004885e-11 10.758793510369737 -0.1857481416327239 VLENAEGAR ddPTM_PC-9_AZD4547_30min_R2 1 VLENAEGAR 9 0 P38646;D6RJI2;A0A3B3ITI4;D6RA73 P38646 HSPA9 Stress-70 protein, mitochondrial 0 93.598 0.028257 3998700.0 15602.0 17255.0 20639.0 25283.0 23620.0 18378.0 16430.0 25248.0 17801.0 21302.0 False True 20563.11145823993 22832.341310084164 20365.313374716956 19454.394968456098 20340.770710877794 17228.82075475104 17892.238170872548 21346.501741321852 18741.924518538242 20556.223463824164 1.0003350807325035 1.1107264595690751 0.990712783919518 0.9463992742972892 0.9895188552836306 0.8381316142564392 0.8704049263893329 1.0384447210786776 0.9117396758952921 1.0 14.327287620225986 -5.548592795232486 3.3601581078712672 0.9384173101519455 1.0561699457222746 0.3448475187776071 0.061843356760809265 0.2504459438022732 5.879670002714285 0.017477503517687558 0.035331943248550525 2.8275298912429068e-06 5.548592795232486 0.11775263557032911 VLENAEGAR ddPTM_PC-9_Lapatinib_30min_R1 1 VLENAEGAR 9 0 P38646;D6RJI2;A0A3B3ITI4;D6RA73 P38646 HSPA9 Stress-70 protein, mitochondrial 0 109.44 0.010912999999999999 4393300.0 24432.0 23396.0 20287.0 15968.0 24026.0 23118.0 18849.0 19574.0 22223.0 16193.0 False True 24083.595199719934 23341.827999445966 18619.08117008464 17142.339987686464 22612.837916933433 22129.297030690126 19824.908991134685 20483.479498400182 19720.011721435483 18991.938474183768 1.2680956834636647 1.2290387329958505 0.9803676015165085 0.9026113901426381 1.1906545478583794 1.1651942249481826 1.0438591625643268 1.078535481053917 1.0383359101674325 1.0 14.213099545930147 -5.158802540575601 5.830392651870239 1.0567366420686617 1.2565061588628967 0.4969309592470348 0.07993032062208849 0.20419525363777521 9.552404761730374 0.022076699287844385 0.060844886068196304 6.937411556197592e-06 5.158802540575601 0.19976951679423505 VLENGEDHGVAGS(ph)PASPASIEEER ddPTM_PC-9_AZD4547_30min_R2 1 VLENGEDHGVAGSPASPASIEEER 24 0 H0Y7I6;E9PI60;Q9ULD4 H0Y7I6 BRPF3 Bromodomain and PHD finger-containing protein 3 1 VLENGEDHGVAGS(0.693)PAS(0.278)PAS(0.029)IEEER 103.78 1.0288e-06 2698800.0 11913.0 13205.0 16401.0 20072.0 18587.0 16165.0 15532.0 20387.0 14104.0 15071.0 True False 15701.086194206666 17473.25801215077 16183.512023776968 15444.710509308665 16006.515884973996 15154.199994588662 16914.317910529047 17236.657596654335 14849.508646113325 14543.368877255376 1.0796044800020073 1.2014587651336754 1.1127760122406467 1.061976123940782 1.1006057826125046 1.0420006617784807 1.1630261223024907 1.1851901538171832 1.0210501274802104 1.0 13.828073878486602 -8.414869219820774 6.497336059097394 1.000695712236345 1.1172028833621646 0.4361567449451248 0.049263243623853356 0.2205543142345817 10.637191467784458 0.04939318134333087 0.01279282363781538 3.847076125660457e-09 8.414869219820774 0.11650717112581965 VLENGEDHGVAGSPAS(ph)PASIEEER ddPTM_PC-9_AZD4547_30min_R2 1 VLENGEDHGVAGSPASPASIEEER 24 0 H0Y7I6;E9PI60;Q9ULD4 H0Y7I6 BRPF3 Bromodomain and PHD finger-containing protein 3 1 VLENGEDHGVAGS(0.285)PAS(0.695)PAS(0.02)IEEER 110.25 3.6631e-07 3297000.0 6234.8 7408.9 9441.0 10614.0 10069.0 9825.5 5737.4 11313.0 8524.1 9776.8 True False 8217.336708103732 9803.682036063907 9315.806171360186 8167.106284665309 8671.09315359139 9211.109931755707 6248.017485183454 9564.835796877938 8974.666523704944 9434.517207826315 0.8709864561259285 1.0391291700577274 0.9874173702955723 0.8656623444271598 0.9190818101850899 0.9763202216764963 0.6622508971630757 1.0138129579056274 0.9512586946431232 1.0 13.203732977400792 -4.4791498208572005 19.416066602514505 0.9288077400182595 0.4626021768995307 0.030629173561772083 0.10285723024795275 26920824.090614438 267632452.41492483 0.025674823932661427 480516263.82986766 3.3177998191847183e-05 4.4791498208572005 -0.4662055631187288 VLENGEDHGVAGSPAS(ph)PASIEEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLENGEDHGVAGSPASPASIEEER 24 0 H0Y7I6;E9PI60;Q9ULD4 H0Y7I6 BRPF3 Bromodomain and PHD finger-containing protein 3 1 VLENGEDHGVAGS(0.03)PAS(0.853)PAS(0.117)IEEER 79.917 8.0887e-05 2411000.0 7874.8 9819.7 11662.0 10242.0 11396.0 11458.0 11517.0 9124.9 9390.9 8476.8 True False 9207.848105610361 10794.534919863552 11940.066308381292 9668.173945012011 9163.035606870495 10857.122309343795 10426.0263841407 8885.381043630721 9528.224146662651 10013.576737688121 0.9195363801382539 1.0779899333308285 1.1923877572578476 0.9655065515825013 0.9150612060906826 1.0842401864741116 1.0411890433615234 0.8873333950883696 0.9515305466029188 1.0 13.289669760321058 -7.743937884625412 24.918044688933858 0.9395739746248022 1.031650740161314 0.16878389341222122 0.08240236234560402 375.1649174262207 534148.692629691 0.04077776742015063 0.023475199096638224 1.8032756376013306e-08 7.743937884625412 0.09207676553651178 VLENGEDHGVAGSPAS(ph)PASIEEER ddPTM_PC-9_Lapatinib_30min_R1 1 VLENGEDHGVAGSPASPASIEEER 24 0 H0Y7I6;E9PI60;Q9ULD4 H0Y7I6 BRPF3 Bromodomain and PHD finger-containing protein 3 1 VLENGEDHGVAGS(0.006)PAS(0.948)PAS(0.046)IEEER 101.22 1.763e-06 2314300.0 15600.0 16491.0 17434.0 15668.0 17327.0 18361.0 13528.0 18731.0 19285.0 14961.0 True False 15377.54113931036 16452.816102704022 16000.643817186152 16820.27698691581 16307.85992619268 17575.742831581505 14228.41364698764 19601.31064087737 17112.920219947053 17546.98891572058 0.8763635295588189 0.9376432721151221 0.9118740482505784 0.9585848072113559 0.9293822435587368 1.001638680915514 0.8108749435773687 1.1170754557960823 0.9752624967247435 1.0 14.098935863124263 -7.771235796360061 24.999999256312258 1.0346266937533455 0.9237772100447108 0.4360758136273035 0.058442527512733385 188.65673255894131 481435.22094335296 0.029313307504285496 0.014357190118341247 1.6934181243640374e-08 7.771235796360061 -0.11084948370863468 VLEQLTGQTPVFSK ddPTM_PC-9_Lapatinib_30min_R1 2 VLEQLTGQTPVFSK 14 0 Q5VVC8;P62913-2;P62913 Q5VVC8 RPL11 60S ribosomal protein L11 0 ; 92.906 0.018258 10253400.0 64066.0 65173.0 60062.0 60892.0 72338.0 67682.0 60900.0 63987.0 63035.0 63154.0 False True 63152.40709173453 65022.095922717184 55123.934206024685 65370.20080975727 68083.22106197996 64787.39863444793 64053.104014011486 66960.06961602786 55935.33451202296 74070.08475258459 0.8526034134115245 0.8778455720674508 0.7442131920080083 0.8825452411471185 0.9191729871701582 0.8746769880290605 0.8647634767526903 0.9040096260142508 0.7551676861024674 1.0 16.17660336751495 -5.906261829797355 20.628531414570247 0.881867789537073 0.8273781216093793 0.15314628451221446 0.0650659101088537 9.53569190652713 2086.9466222165056 0.017600798528605292 0.026106331559358698 1.2409039591656582e-06 5.906261829797355 -0.05448966792769372 VLES(ph)PENK ddPTM_PC-9_AZD4547_30min_R2 1 VLESPENK 8 0 Q8N3D4 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 VLES(1)PENK 88.134 0.011204 23614000.0 131050.0 124760.0 124390.0 132610.0 137250.0 155970.0 117920.0 133160.0 112880.0 141870.0 True False 172721.17399066404 165086.23018522767 122740.50732501774 102038.81330407635 118195.2066074503 146217.17124379778 128414.65155869097 112583.18171239005 118846.60635091279 136903.17448186714 1.2616301604718523 1.2058612286385908 0.8965497534264609 0.7453356263670234 0.8633489110444643 1.0680334608542206 0.9379961570993338 0.8223562538887783 0.8681070165151944 1.0 17.062796374328087 -5.237049282794219 4.828400903270056 0.8935280746148265 1.2431861768940207 0.7096718348036535 0.0854576115482058 0.10386471181991075 6.670202817525891 0.023916434212121997 0.06309111538282669 5.793629478479031e-06 5.237049282794219 0.34965810227919414 VLES(ph)PENK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VLESPENK 8 0 Q8N3D4 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 VLES(1)PENK;VLES(1)PENK 101.66 0.0045165 14825500.0 112779.0 110307.0 96093.0 95783.0 119764.0 103474.0 103152.0 92293.0 85260.0 64746.0 True False 131870.2572132157 121257.54996643375 98384.22155473173 90416.58904267586 96297.1039330678 98047.64128443346 93380.69580419223 89870.40654251663 86506.76620392695 76483.93727094588 1.7241562335639529 1.5853988993385166 1.2863383484849067 1.1821644160704394 1.2590500354595158 1.2819376823802586 1.220919047007076 1.175023276118081 1.1310448872091272 1.0 16.222869172416488 -1.522878745285822 0.46467343470880773 1.146897935637293 16.736633230290945 0.8694452517584261 0.07365014918806741 32.504471708366324 0.37841779162481776 0.04628988966902321 485.15545047247906 0.029999999999621156 1.522878745285822 15.589735294653652 VLES(ph)PENK ddPTM_PC-9_Lapatinib_30min_R1 1 VLESPENK 8 0 Q8N3D4 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 VLES(1)PENK 113.44 0.0037138000000000006 28625000.0 219220.0 203910.0 170310.0 163190.0 165400.0 183850.0 163340.0 140370.0 189000.0 122270.0 True False 216093.88259997516 203437.8589231928 156307.76921561174 175191.5369858817 155671.49718891148 175987.16407528258 171796.94597124172 146892.1026458787 167712.82974176804 143404.20658546596 1.5068866370470635 1.418632436015383 1.0899803634592513 1.221662468328439 1.085543450192547 1.2272106116384935 1.1979909799149042 1.0243221321289069 1.1695112279835016 1.0 17.129727818776345 -5.167096083353244 4.069768278961178 1.1357474770956766 1.4873247708048614 0.7584829452888298 0.0761104763296959 0.10305128216054339 3.0165900962171843 0.0189942013250651 0.05693494627274613 6.8061876187452305e-06 5.167096083353244 0.3515772937091848 VLETAEDIQER ddPTM_PC-9_Lapatinib_30min_R1 2 VLETAEDIQER 11 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2;A0A0D9SFF6;A0A1B0GTB7 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 ; 169.58 0.0071988 6411100.0 24925.0 25737.0 26189.0 26423.0 28779.0 24488.0 21621.0 20692.0 24628.0 22929.0 False True 24569.564929314813 25677.407557776573 24035.841512463456 28366.235564544066 27086.275801690954 23440.705324316106 22740.429587634513 21653.425859859824 21854.135295662752 26892.247099027973 0.9136300450772998 0.9548256589797841 0.8937833057964218 1.0548109073997527 1.0072150423855801 0.8716529056868355 0.8456128453637656 0.8051921351207015 0.8126556034974362 1.0 14.714902690475208 -6.875561791417895 5.8229391199844205 0.8510444411293826 0.964982993210023 0.3454482074562215 0.06599075191796 0.21759196127626873 10.281711099479113 0.023536910508140326 0.020771032527216137 1.3317975406812843e-07 6.875561791417895 0.11393855208064041 VLFSSNGGVVK ddPTM_PC-9_Lapatinib_30min_R1 1 VLFSSNGGVVK 11 0 A6NLN1;P26599;P26599-2;P26599-3;A0A0D9SF20;A0A0U1RRM4 A6NLN1;A0A0U1RRM4 PTBP1 Polypyrimidine tract-binding protein 1 0 98.04 0.023687 3384500.0 40850.0 32444.0 33985.0 26971.0 27920.0 36040.0 27094.0 22619.0 31012.0 25590.0 False True 40267.471509027484 32368.877911353404 31190.884485893737 28954.537312618475 26277.800492831982 34498.65321334337 28496.79474803985 23669.961314719196 27519.101989162464 30013.197403468344 1.3416588365348288 1.078488155600937 1.0392389743283166 0.9647268474392026 0.875541520604376 1.1494494488400189 0.9494754712387539 0.7886517719696162 0.9169000429785045 1.0 14.873309401664802 -1.522878819514634 0.7118686413683925 0.9381664229469806 55.204030050766484 0.6428453539382908 0.08794261896410274 201.01503394862237 1.0169740527471365 0.03611557789008884 17396.293806965845 0.0299999948720769 1.522878819514634 54.265863627819506 VLGAGGAGPAPAT(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 2 VLGAGGAGPAPATPSR 16 0 B7WPE2;Q32P44;H7C355;G3V195 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 VLGAGGAGPAPAT(0.89)PS(0.11)R;VLGAGGAGPAPAT(0.998)PS(0.002)R 125.39 7.8088e-05 28625000.0 53514.0 59153.0 66421.0 60560.0 71168.0 70027.0 69272.0 90559.0 69356.0 53243.0 True False 70530.33883965206 78273.05045003821 65540.21414128957 46598.82764267302 61287.55164910046 65648.20061992324 75437.07380235441 76565.18738879765 73022.01656691964 51378.97877590791 1.3727469973133137 1.5234450414328045 1.2756231381543535 0.9069629010322731 1.1928526628839649 1.2777249019730672 1.4682478242975037 1.4902045391509375 1.421243051276067 1.0 15.648890594631013 -7.087535960724402 7.006130085183258 1.3851257092389728 1.2496198424476002 0.030428900439078532 0.19469317937653535 0.713805225117 49.16031816822465 0.07906371723603207 0.061291022672211454 8.174553476902095e-08 7.087535960724402 -0.13550586679137266 VLGAGGAGPAPAT(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLGAGGAGPAPATPSR 16 0 B7WPE2;Q32P44;H7C355;G3V195 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 VLGAGGAGPAPAT(0.976)PS(0.024)R 98.676 0.0049341 9476300.0 25143.0 20103.0 21235.0 26554.0 23684.0 25281.0 37236.0 24394.0 27818.0 23158.0 True False 29399.21330311389 22098.692983901423 21741.322934185955 25066.265469229547 19043.290217016576 23955.219855343046 33708.736514705495 23753.68334757948 28224.785623514428 27356.362081372878 1.0746755440531328 0.8078081770583292 0.7947446692478808 0.9162865074920663 0.6961192486183415 0.8756727149643303 1.232208303663958 0.8683056349716002 1.0317448474895303 1.0 14.739588769271787 -7.029725792839214 24.77478961999134 1.0266402454132535 0.8479766662213508 0.3181572221812138 0.12313824710647903 737.2478517668591 614452.6888635416 0.04564516726745011 0.035415096338353526 9.338437299219724e-08 7.029725792839214 -0.17866357919190268 VLGAS(ph)SPEAR ddPTM_PC-9_Lapatinib_30min_R1 1 VLGASSPEAR 10 0 B4DTX8;Q9UIL8 B4DTX8 PHF11 PHD finger protein 11 1 VLGAS(0.589)S(0.411)PEAR 82.26100000000001 0.038149 0.0 13475.0 25031.0 22802.0 19029.0 23603.0 20532.0 27172.0 22685.0 23308.0 20583.0 True False 13282.84402898765 24973.042257400044 20927.307578265372 20428.45613888312 22214.717945283424 19653.894222429688 28578.833206382908 23739.027915664046 20682.80759587898 24140.744124876484 0.5502251281185646 1.034476904614796 0.8668874277450405 0.8462231335210609 0.9202167849661131 0.814137879129285 1.1838422651161393 0.9833594106654534 0.856759323113235 1.0 14.559182526591979 -7.204855720883847 24.999359338834296 1.0046048154470708 0.8529229521751007 0.2624646117008361 0.13613135583993222 423.99608310431245 187326.63556320508 0.050363677040835136 0.03901152240912083 6.239420839382757e-08 7.204855720883847 -0.15168186327197009 VLGS(ph)EGEEEDEALS(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 3 VLGSEGEEEDEALSPAK 17 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;F5GZ28;M0QY71;M0R1G7 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 2 VLGS(1)EGEEEDEALS(1)PAK;VLGS(1)EGEEEDEALS(1)PAK;VLGS(1)EGEEEDEALS(1)PAK 150.7 0.00061457 5095600.0 38362.2 34080.9 30953.9 35540.9 37973.8 40290.2 40659.0 37350.3 39601.8 35335.1 True False 50560.58161667041 45096.88443667622 30543.431061081043 27347.494606431275 32701.793345500908 37770.84742480524 44277.57223308016 31578.66935950943 41695.07029932296 34098.028904167375 1.4828007143395618 1.3225657284595882 0.8957535682465241 0.802025673779898 0.9590523087832851 1.107713514202253 1.2985375887128967 0.9261142175772502 1.2228000162856068 1.0 15.05740072371463 -5.080049612987852 4.375182258745211 1.0271381162659374 1.4533625271956754 0.5371085857488469 0.14290923901096708 0.16522012972582545 5.664241220080791 0.039617708860330544 0.12377793059778223 8.316687573951769e-06 5.080049612987852 0.42622441092973795 VLGS(ph)EGEEEDEALS(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLGSEGEEEDEALSPAK 17 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;F5GZ28;M0QY71;M0R1G7 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 2 VLGS(1)EGEEEDEALS(1)PAK 108.96 0.0085858 0.0 6492.6 4955.3 6792.4 7623.8 7648.4 5806.9 8874.5 7331.5 5246.3 4892.0 True False 7591.668945304749 5447.229435563184 6954.356576320451 7196.663202693087 6149.750924498799 5502.375941536782 8033.843114183957 7139.05589336636 5323.0172124755145 5778.880874949309 1.3136918911434285 0.9426097463223735 1.2034088825860167 1.2453385626773652 1.0641767943611993 0.9521525119835677 1.3902074273601337 1.2353699700426826 0.9211155806222094 1.0 12.496574415366185 -8.267507035798388 24.949441546717384 0.9605577655514719 1.1612920435949745 0.26144792853266585 0.1393044157371332 743.9610470667204 3059025.5270710643 0.12338520338282796 0.03513446072659728 5.40123364411964e-09 8.267507035798388 0.20073427804350263 VLGS(ph)EGEEEDEALS(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 4 VLGSEGEEEDEALSPAK 17 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;F5GZ28;M0QY71;M0R1G7 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 2 VLGS(1)EGEEEDEALS(1)PAK;VLGS(1)EGEEEDEALS(1)PAK;VLGS(1)EGEEEDEALS(1)PAK;VLGS(1)EGEEEDEALS(1)PAK 162.37 1.7384e-07 7911800.0 34431.9 42684.4 36683.200000000004 38436.6 48070.0 39531.0 37575.0 42263.7 37238.9 40142.4 True False 33940.894791962855 42585.566894321695 33667.248897246944 41263.35578473884 45242.617109256185 37840.351281261814 39520.44964411298 44227.425793222385 33044.66293899854 47080.9603536142 0.7209048952493884 0.9045178045322643 0.7150926541085829 0.8764340292725407 0.9609535737896882 0.8037293843849337 0.839414687960569 0.9393909015670118 0.7018689230382669 1.0 15.522856128202484 VLGS(ph)EGEEEDEALSPAK ddPTM_PC-9_AZD4547_30min_R2 5 VLGSEGEEEDEALSPAK 17 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;F5GZ28;M0QY71;M0R1G7 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 VLGS(1)EGEEEDEALSPAK;VLGS(1)EGEEEDEALSPAK;VLGS(1)EGEEEDEALSPAK;VLGS(1)EGEEEDEALSPAK;VLGS(1)EGEEEDEALSPAK 261.17 2.3620999999999998e-58 33076800.0 196379.9 199452.30000000002 231739.5 313233.7 271098.1 253426.69999999998 192057.7 262731.0 209438.19999999998 229999.9 True False 258824.6232443284 263921.355472692 228666.4828141005 241022.50987742303 233460.80830883243 237579.88838655315 209150.46323493568 222131.9609077641 220508.67567544067 221947.67350752093 1.166151548939565 1.1891152148695479 1.0302720420556781 1.0859429435256311 1.0518731943406534 1.070431983503096 0.9423413182470165 1.000830319134825 0.99351649959047 1.0 17.759860060609377 -4.5511470324728585 0.39706735156381845 0.9819718212902757 1.3813302526805786 0.7288728668488341 0.03845840164153271 3.543319970116395 0.384144831117957 0.031818410690046754 0.7001540462334653 2.8109490090623122e-05 4.5511470324728585 0.3993584313903029 VLGS(ph)EGEEEDEALSPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 VLGSEGEEEDEALSPAK 17 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;F5GZ28;M0QY71;M0R1G7 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 VLGS(1)EGEEEDEALSPAK;VLGS(1)EGEEEDEALSPAK;VLGS(1)EGEEEDEALSPAK;VLGS(1)EGEEEDEALSPAK;VLGS(1)EGEEEDEALSPAK;VLGS(1)EGEEEDEALSPAK 260.07 4.2632e-58 33119400.0 181476.3 179223.3 163469.2 204021.7 208482.1 199476.30000000002 211786.3 158888.30000000002 169218.9 151369.5 True False 212196.65326969262 197015.4047784743 167366.92568839356 192591.0255962759 167631.52910627736 189015.4116700431 191724.36846396985 154717.65048106993 171693.4062817937 178811.59210969755 1.186705239666531 1.1018044325538416 0.9359959481022746 1.077061186716155 0.9374757370508651 1.0570646423979364 1.07221442526137 0.8652551473628933 0.960191698178399 1.0 17.448080741925992 -5.030455863436426 3.679206092848106 0.9904132910824164 1.1776411985080233 0.5031232753739705 0.064460221256031 0.1825441810399493 5.137743422556128 0.016949753096465386 0.06580939617260212 9.322752109727547e-06 5.030455863436426 0.1872279074256069 VLGS(ph)EGEEEDEALSPAK ddPTM_PC-9_Lapatinib_30min_R1 3 VLGSEGEEEDEALSPAK 17 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;F5GZ28;M0QY71;M0R1G7 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 VLGS(1)EGEEEDEALSPAK;VLGS(1)EGEEEDEALSPAK;VLGS(1)EGEEEDEALSPAK 276.14 1.1309999999999996e-82 22681000.0 120137.8 113226.4 114439.7 108469.3 124500.1 120035.2 107849.3 110825.4 122332.7 100938.0 True False 118424.61294142569 112964.23122740902 105030.90961601665 116446.49416497762 117177.24889461437 114901.57431171782 113433.2090433223 115974.75267201394 108554.30310555975 118384.99880856914 1.0003346212210602 0.9542106885524777 0.8871977925670607 0.9836254199172133 0.9897981169395649 0.9705754569252132 0.9581721517499528 0.9796406118949866 0.9169599543696764 1.0 16.85312675544065 VLGSEGEEEDEALS(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 8 VLGSEGEEEDEALSPAK 17 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;F5GZ28;M0QY71;M0R1G7 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 VLGSEGEEEDEALS(1)PAK;VLGSEGEEEDEALS(1)PAK;VLGSEGEEEDEALS(1)PAK;VLGSEGEEEDEALS(1)PAK;VLGSEGEEEDEALS(1)PAK;VLGSEGEEEDEALS(1)PAK;VLGSEGEEEDEALS(1)PAK;VLGSEGEEEDEALS(1)PAK 235.02 2.7906e-37 143787100.0 214664.6 196272.6 202445.5 203517.2 214231.3 235124.1 223881.1 224922.9 214459.8 201870.8 True False 282923.4774989414 259713.8796301147 199760.94039446034 156599.45384939568 184488.98189641288 220421.752857882 243806.08418484035 190166.23401905707 225795.70719964066 194803.36473668943 1.452354161753631 1.333210440082301 1.02544912745461 0.8038847484029191 0.9470523373442844 1.131508961130216 1.2515496563131063 0.9761958386914915 1.159095519242405 1.0 17.571659070989575 -5.164514801076487 3.6681518577400447 1.0351325492035655 1.426502604764763 0.5987643328381287 0.11804805290149503 0.174458724681149 4.2696059102321104 0.03395605034163176 0.10644428600325812 6.846761484250201e-06 5.164514801076487 0.39137005556119764 VLGSEGEEEDEALS(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 VLGSEGEEEDEALSPAK 17 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;F5GZ28;M0QY71;M0R1G7 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 VLGSEGEEEDEALS(1)PAK;VLGSEGEEEDEALS(1)PAK;VLGS(0.001)EGEEEDEALS(0.999)PAK;VLGSEGEEEDEALS(1)PAK;VLGSEGEEEDEALS(1)PAK;VLGS(0.001)EGEEEDEALS(0.999)PAK;VLGSEGEEEDEALS(1)PAK;VLGSEGEEEDEALS(1)PAK 237.06 2.0475e-37 113392300.0 145037.4 161381.4 148359.49999999997 167859.9 176486.6 145122.19999999998 182047.8 157915.9 143759.7 127932.2 True False 169589.36720077362 177402.27885948337 151896.95313653725 158455.25401213864 141905.31764965854 137511.73635896776 164802.91447206447 153770.77495072645 145861.9136458676 151125.29514926168 1.1221772439436797 1.1738754831497185 1.0051060809278383 1.0485025280224425 0.9389911696086557 0.9099187281861171 1.0905051620199904 1.0175052085016734 0.9651720679969849 1.0 17.20538563151227 -5.270093077426019 22.63467108172088 0.9975901768298703 1.148026364991752 0.5917140963909127 0.05019121688721812 108.7891322738987 284552.97090126947 0.013743495090783563 0.0294633898701921 5.3691671274993505e-06 5.270093077426019 0.15043618816188165 VLGSEGEEEDEALS(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 7 VLGSEGEEEDEALSPAK 17 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;F5GZ28;M0QY71;M0R1G7 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 VLGSEGEEEDEALS(1)PAK;VLGSEGEEEDEALS(1)PAK;VLGSEGEEEDEALS(1)PAK;VLGSEGEEEDEALS(1)PAK;VLGSEGEEEDEALS(1)PAK;VLGSEGEEEDEALS(1)PAK;VLGS(0.025)EGEEEDEALS(0.975)PAK 173.19 7.123200000000001e-06 135913200.0 128183.8 158180.0 148118.5 170701.5 179543.0 169010.4 159136.0 167605.1 160491.5 132720.8 True False 126355.87550597022 157813.74392855 135940.7686839446 183255.45775351126 168982.63373511937 161782.21917448504 167375.28342157174 175392.64481849922 142415.25721958157 155661.41344065013 0.8117353730322294 1.0138270007982453 0.8733106405703779 1.1772696502166997 1.0855781789463725 1.0393212781417318 1.0752522396013564 1.1267573699976208 0.9149040476487836 1.0 17.248051836727647 -4.16184732815336 0.9116938606004069 1.0577382678704768 0.32953156722228527 0.38562906975432776 0.08570526159604493 5.775115987776407 1.6992393311820062 0.028104293311031283 5.47383138116238 6.888944276731161e-05 4.16184732815336 -0.7282067006481915 VLGTS(ph)PEAIDSAENR ddPTM_PC-9_AZD4547_30min_R2 2 VLGTSPEAIDSAENR 15 0 F8VPD4;P27708 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 VLGT(0.053)S(0.947)PEAIDSAENR;VLGT(0.052)S(0.948)PEAIDSAENR 164.7 0.00014199999999999998 8119400.0 21306.0 19153.4 27937.0 41678.0 30302.0 25497.0 24098.0 30357.0 24926.0 27741.0 True False 28080.86480766955 25344.361984848827 27566.53712628846 32069.78101868107 26095.09035059353 23902.66855935831 26242.675315988225 25666.02318446242 26243.53747256245 26769.79603370325 1.0489756728932735 0.9467521513029163 1.0297626882021107 1.197983764176056 0.9747960095676388 0.8928969249248213 0.9803091246174839 0.9587679768702319 0.9803413309358712 1.0 14.708318526287353 -6.496542153667166 24.97193672476969 0.9579842057354856 1.0512323426638186 0.33343035465345705 0.06318122123103705 913.7118403135396 866367.7414603245 0.02058238682115448 0.023260212418224326 3.1875561688104255e-07 6.496542153667166 0.093248136928333 VLGTS(ph)PEAIDSAENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VLGTSPEAIDSAENR 15 0 F8VPD4;P27708 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 VLGT(0.055)S(0.945)PEAIDSAENR;VLGT(0.052)S(0.947)PEAIDSAENR 159.41 6.3124e-05 5502200.0 18303.5 16622.1 20443.4 24313.0 26205.0 21335.0 22359.2 23579.0 25711.0 17651.2 True False 21401.921039396457 18272.232236368087 20930.848188026233 22950.82143380952 21070.318364166487 20216.155041879036 20241.174709410323 22960.07623401559 26086.974734566815 20851.222833177675 1.0264108350203103 0.8763146594593965 1.0038187378978014 1.1006942670667277 1.0105075626854938 0.9695428994078877 0.9707428130883208 1.1011381163450225 1.2511004722973948 1.0 14.347844373465415 -7.8736317128266915 4.9090507266715715 1.1404576260095578 0.9939380483406722 0.34525371535723515 0.07748442390555334 0.21252155245915696 8.136796376207979 0.04408157393337973 0.020467254975602 1.3377294470513983e-08 7.8736317128266915 -0.14651957766888557 VLGTS(ph)PEAIDSAENR ddPTM_PC-9_Lapatinib_30min_R1 2 VLGTSPEAIDSAENR 15 0 F8VPD4;P27708 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 VLGT(0.049)S(0.951)PEAIDSAENR;VLGT(0.029)S(0.971)PEAIDSAENR 193.98 1.436e-09 5919100.0 26002.0 22281.4 25314.0 18298.1 22302.0 25023.0 19106.2 23354.0 27696.0 15268.2 True False 25631.20671181719 22229.808787265127 23232.78063486579 19643.80331467221 20990.24020741902 23952.824621462005 20095.425548645413 24439.112097968624 24576.58482819049 17907.288026402322 1.4313282208912261 1.2413833269722208 1.29739246951362 1.0969725446817846 1.1721618693166282 1.33760201914138 1.1221925686914134 1.3647578607065374 1.372434775827307 1.0 14.128259244114304 -4.421349905332365 1.825537678726967 1.227870779117236 1.7456613493570794 0.21672605904373676 0.11838817779465015 4.8290528903914485 6.97947550613921 0.03139224158209919 5.947844722447817 3.7900949897593166e-05 4.421349905332365 0.5177905702398433 VLHS(ph)PPAVR ddPTM_PC-9_Lapatinib_30min_R1 1 VLHSPPAVR 9 0 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;Q9Y4B5-4 Q9Y4B5;Q9Y4B5-4 MTCL1 Microtubule cross-linking factor 1 1 VLHS(1)PPAVR 67.153 0.026363 20916000.0 24478.0 24843.0 16808.0 20156.0 20970.0 20020.0 17043.0 17835.0 23713.0 17791.0 True False 24128.939231284567 24785.477559849372 15426.111120756272 21638.339478444926 19736.58582860626 19163.7912688994 17925.40314796054 18663.679209868555 21042.19223103991 20866.150644982627 1.1563675371569548 1.1878318134259789 0.739288783217213 1.0370067697967078 0.9458661621113152 0.9184152647487682 0.8590661235483218 0.8944476404590864 1.0084367063696826 1.0 14.348876858456006 -5.232600189057481 24.902652625128045 0.9236565775745353 1.1720997907884962 0.596513863090292 0.0811767098270812 433.5561412247477 374374.4950000375 0.019694788116189264 0.052087219902889614 5.853286890266678e-06 5.232600189057481 0.2484432132139609 VLIAAHGNSLR ddPTM_PC-9_AZD4547_30min_R2 1 VLIAAHGNSLR 11 0 P18669;P15259 P18669 PGAM1;PGAM2 Phosphoglycerate mutase 1;Phosphoglycerate mutase 2 0 123.96 0.00044964 16676000.0 18621.0 18831.0 34134.0 61496.0 45255.0 50865.0 34062.0 43147.0 31785.0 42198.0 False True 24542.090659138958 24917.752489724433 33681.36085724059 47319.04730372887 38972.124408161515 47684.40350910936 37093.45201316253 36479.62256942387 33465.0902096364 40720.66086407154 0.6026938202467342 0.6119191575230486 0.8271319802414642 1.1620402591618837 0.9570602141810329 1.1710125154472146 0.9109246074611389 0.8958504551582657 0.821820901221256 1.0 15.313473354950828 -5.4292631564078695 3.53572092057109 0.9879542439368254 0.6089214278938895 0.6749290507069166 0.10484438496961117 0.14163484855178435 3.269779106150002 0.029823731922990305 0.06719728740612016 3.7216612756641e-06 5.4292631564078695 -0.3790328160429359 VLIAAHGNSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLIAAHGNSLR 11 0 P18669;P15259 P18669 PGAM1;PGAM2 Phosphoglycerate mutase 1;Phosphoglycerate mutase 2 0 114.86 0.0011886 6468400.0 16416.0 15768.0 22930.0 20514.0 21716.0 27907.0 22804.0 20439.0 23281.0 20664.0 False True 19194.904569220755 17333.342832918355 23476.73816250927 19364.667087285343 17460.905689610354 26443.507792534245 20643.8400333372 19902.497906910594 23621.440581675164 24410.219623865996 0.7863470654911191 0.7100854928798533 0.9617585799824572 0.7933016329092103 0.7153112900524147 1.083296594623028 0.8457048052592535 0.8153346513708472 0.9676865241548405 1.0 14.575197654956797 -6.737502931083737 24.99999986069061 0.9248193478880805 0.7980865767967567 0.3683321563004981 0.09612286373727816 307.55941328850696 321224.1709682429 0.032208314726264904 0.03219181751252849 1.8301937541641256e-07 6.737502931083737 -0.12673277109132386 VLIAAHGNSLR ddPTM_PC-9_Lapatinib_30min_R1 1 VLIAAHGNSLR 11 0 P18669;P15259 P18669 PGAM1;PGAM2 Phosphoglycerate mutase 1;Phosphoglycerate mutase 2 0 139.15 4.4668999999999995e-05 0.0 15191.0 15031.0 17625.0 13874.0 16851.0 20649.0 16412.0 14711.0 20067.0 14444.0 False True 14974.373554311785 14996.196643001895 16175.940534467474 14894.340242307237 15859.857310340683 19765.890405170012 17261.733055467263 15394.526765145853 17806.843145121984 16940.62615457979 0.883932708134496 0.8852209184102542 0.9548608408488143 0.8792083661134714 0.9362025444409605 1.166774487838304 1.0189548425162942 0.9087342241469653 1.051132525010477 1.0 14.048199579686633 -6.540726748017507 24.999962631118603 1.0259697062091835 0.904072544230193 0.49195670848090434 0.06235833657849191 224.60582628268216 314606.5581914669 0.02129707421770231 0.021300731459883197 2.879209403030816e-07 6.540726748017507 -0.12189716197899048 VLIGGDETPEGQR ddPTM_PC-9_Lapatinib_30min_R1 1 VLIGGDETPEGQR 13 0 O60701;O60701-2;O60701-3 O60701 UGDH UDP-glucose 6-dehydrogenase 0 127.83 0.00051753 8756400.0 28695.0 29939.0 35003.0 37347.0 27398.0 35118.0 27765.0 31464.0 27225.0 23818.0 False True 28285.80403798149 29869.678084946678 32125.188455487365 40093.62296593979 25786.503506540485 33616.08500405639 29202.53584481164 32925.93230497922 24158.633808040388 27934.90956450992 1.0125611458544819 1.0692598812954381 1.1500015198295472 1.4352515755725581 0.9230924283821956 1.203371893022491 1.0453778551662893 1.178666149927694 0.8648187584875118 1.0 14.769781529318955 -8.258209368568666 24.965211245387383 0.9324093731410794 1.1293034186179178 0.2543224431010648 0.13337651935615655 354.1829321586178 2737583.639259987 0.097215491697165 0.03327101483337376 5.518113529941942e-09 8.258209368568666 0.19689404547683842 VLIS(ph)VGSYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLISVGSYK 9 0 Q8TEV9-2;Q8TEV9 Q8TEV9-2 SMCR8 Smith-Magenis syndrome chromosomal region candidate gene 8 protein 1 VLIS(0.577)VGS(0.423)YK 75.294 0.026182 3078900.0 11914.0 13270.0 16944.0 27884.0 36362.0 37705.0 38810.0 36706.0 32353.0 32271.0 True False 13930.804887773891 14587.357901625233 17348.00922047784 26321.749881147713 29237.127126801057 35727.683424141025 35133.63583993233 35742.50639322179 32826.101419137354 38121.47684290454 0.3654319308032474 0.3826545850187948 0.45507180353918486 0.69047036109376 0.766946339652182 0.9372061730811704 0.9216231570648519 0.9375950082026913 0.8610920703416346 1.0 15.21831639052509 -5.975036162375895 1.1038708897803526 0.9327481617721509 0.34236227368459565 0.96912054750738 0.0410187806801984 0.07822584952025262 0.19324575230309698 0.015606787220349385 0.032663568117868864 1.059165528024797e-06 5.975036162375895 -0.5903858880875552 down VLISVGS(ph)YK ddPTM_PC-9_AZD4547_30min_R2 1 VLISVGSYK 9 0 Q8TEV9-2;Q8TEV9 Q8TEV9-2 SMCR8 Smith-Magenis syndrome chromosomal region candidate gene 8 protein 1 VLIS(0.028)VGS(0.972)YK 101.35 0.0035269 4431000.0 44709.0 48344.0 62315.0 106250.0 90363.0 91950.0 93438.0 96283.0 86818.0 83595.0 True False 58925.53199502945 63970.25258155371 61488.662384102296 81755.7040461362 77817.65722891853 86200.35196427003 101753.80098660919 81404.67471323234 91407.02223754025 80668.36449433769 0.7304664271353312 0.7930029694111864 0.7622401020466746 1.0134791322300187 0.9646613975219585 1.0685769136960828 1.261384207110726 1.0091276205177846 1.133121054461893 1.0 16.29971538594839 -5.935361530750715 1.1515811866391397 1.1011941811366 0.7343837495736669 0.7516083871570652 0.07994740455722565 0.24208866282793318 0.6483963963241509 0.030083751365211603 0.06462904153471723 1.1604821620857952e-06 5.935361530750715 -0.366810431562933 VLISVGS(ph)YK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLISVGSYK 9 0 Q8TEV9-2;Q8TEV9 Q8TEV9-2 SMCR8 Smith-Magenis syndrome chromosomal region candidate gene 8 protein 1 VLIS(0.001)VGS(0.999)YK 100.69 0.0037398 2480500.0 18460.0 17398.0 22866.0 37060.0 45773.0 47343.0 58736.0 49330.0 46647.0 45397.0 True False 21584.913398380573 19125.15846062363 23411.212159787898 34983.6483501411 36804.10923422982 44860.249737411716 53172.10086818512 48035.139769455425 47329.12412754611 53627.11673754576 0.4024999797027761 0.3566322342896649 0.4365554887905635 0.6523499766238248 0.6862966251635583 0.8365217536672799 0.9915151905035747 0.8957248252696897 0.8825595520858898 1.0 15.71067506848313 -6.198721721953655 0.8733438705319349 0.9460085617620259 0.3434986270870871 0.9523114662846426 0.0508188342005594 0.12569569508158257 0.2031526639877042 0.026054372379324182 0.046397968332078925 6.328172047395934e-07 6.198721721953655 -0.6025099346749387 down VLITTDLLAR ddPTM_PC-9_Lapatinib_30min_R1 1 VLITTDLLAR 10 0 P60842;Q14240-2;E7EQG2;Q14240 P60842 EIF4A1;EIF4A2 Eukaryotic initiation factor 4A-I;Eukaryotic initiation factor 4A-II;Eukaryotic initiation factor 4A-II, N-terminally processed 0 114.89 0.0053886 4416200.0 20808.0 15868.0 19409.0 12631.0 19538.0 13837.0 16880.0 13075.0 17704.0 15578.0 False True 20511.274104280128 15831.258620927018 17813.26694090663 13559.925875780806 18388.813253185937 13245.223765622419 17753.96380552567 13682.512232634215 15709.98908861512 18270.636543619767 1.122635987821826 0.8664864293661079 0.9749669585062786 0.7421704133519106 1.006468122185236 0.7249459390208133 0.971721141906546 0.7488798871330098 0.8598490288561489 1.0 14.157239277462637 VLLPEYGGTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLLPEYGGTK 10 0 P61604;B8ZZL8;B8ZZ54 P61604 HSPE1 10 kDa heat shock protein, mitochondrial 0 99.815 0.019481000000000002 5254000.0 58480.0 65949.0 67139.0 77566.0 72208.0 69822.0 67876.0 61885.0 68502.0 62107.0 False True 68379.50896735089 72495.98087824267 68739.84838607526 73220.22849236483 58059.3607494652 66160.41140539384 61446.29390031549 60260.584322577524 69503.71215694818 73366.50746125846 0.9320262246837772 0.9881345505852862 0.9369377221939271 0.9980061887371309 0.7913605643572952 0.9017794862366887 0.8375251327421099 0.8213636768030483 0.947349336393721 1.0 16.162833988298573 -6.241376099376482 24.970341822224324 0.8729401368836114 0.9635990250821982 0.28994196778815806 0.06047788457427401 896.152632169285 1115332.9189044475 0.016770686878106244 0.0216237199709863 5.73619492100878e-07 6.241376099376482 0.0906588881985868 VLLPEYGGTK ddPTM_PC-9_Lapatinib_30min_R1 2 VLLPEYGGTK 10 0 P61604;B8ZZL8;B8ZZ54 P61604 HSPE1 10 kDa heat shock protein, mitochondrial 0 ; 116.52 0.004763300000000001 33333000.0 442040.0 518030.0 546390.0 493370.0 426930.0 429830.0 472140.0 372910.0 491370.0 396610.0 False True 435736.4285397921 516830.53336266876 501467.92332639423 529654.0756340737 401818.8167766752 411447.1728826689 496585.0990012374 390236.7599748851 436026.7362445108 465163.5100503934 0.9367381987735596 1.1110728210531347 1.078046563179618 1.1386406375183937 0.8638227378006159 0.8845216015290942 1.0675495568159248 0.8389238440749767 0.9373622969636503 1.0 18.827378402859893 -6.262395148083697 24.998394866179133 0.9283767556422504 1.0701867177623596 0.40609499650992964 0.07930947281007168 83.83165121045755 2192640.0682172687 0.023785072308041496 0.028565203847334634 5.465184801629834e-07 6.262395148083697 0.1418099621201092 VLLQAS(ph)QDENFGNTTPR ddPTM_PC-9_AZD4547_30min_R2 2 VLLQASQDENFGNTTPR 17 0 G3V1T4;P57740 G3V1T4 NUP107 Nuclear pore complex protein Nup107 1 VLLQAS(0.746)QDENFGNT(0.127)T(0.127)PR;VLLQAS(1)QDENFGNTTPR 132.4 2.4094e-05 14893000.0 34783.8 35208.2 41532.0 65252.0 57364.0 55940.0 55965.0 70837.0 63228.0 52108.0 True False 45844.32485201425 46588.56211612316 40981.25854347327 50209.159533350365 49399.99877471609 52442.06295683823 60945.77658142918 59890.769322323256 66570.1029974797 50283.71478044084 0.9117131670201621 0.9265139284069959 0.8150006164503582 0.998517308289254 0.9824254033421475 1.042923403448246 1.2120380693340427 1.191056977071617 1.323889917205836 1.0 15.617803614378522 -6.863956640928384 1.3225038900686261 1.2032051483342971 0.9036393124464006 0.6590729297617103 0.086528547805699 0.24000540353010724 0.8734977958050669 0.04190799002372276 0.03448069899514065 1.367865383657343e-07 6.863956640928384 -0.29956583588789654 VLLQAS(ph)QDENFGNTTPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VLLQASQDENFGNTTPR 17 0 G3V1T4;P57740 G3V1T4 NUP107 Nuclear pore complex protein Nup107 1 VLLQAS(1)QDENFGNTTPR;VLLQAS(1)QDENFGNTTPR;VLLQAS(1)QDENFGNTTPR;VLLQAS(0.365)QDENFGNT(0.317)T(0.317)PR 152.89 2.6476e-05 20893600.0 41785.2 41806.8 42734.4 52467.5 60159.9 51397.7 47220.8 51305.4 42700.4 39580.9 True False 48858.60906468102 45957.102812484234 43753.35016711451 49527.9160769301 48371.99945645565 48702.314131520274 42747.703975013574 49958.68761256473 43324.812568779795 46756.603847768 1.0449563279607905 0.982900788990432 0.9357683528420585 1.0592710334177617 1.0345490364087846 1.0416135930250023 0.914260242557249 1.0684840963903668 0.9266030678754692 1.0 15.51288252349259 -1.741413672875984 6.0098253511662 1.0017240767231934 1.0018254734245338 0.0 0.055051581138602694 0.0 0.0 0.012006008630977083 0.0 0.0181378717658183 1.741413672875984 0.0001013967013403505 VLLQAS(ph)QDENFGNTTPR ddPTM_PC-9_Lapatinib_30min_R1 2 VLLQASQDENFGNTTPR 17 0 G3V1T4;P57740 G3V1T4 NUP107 Nuclear pore complex protein Nup107 1 VLLQAS(1)QDENFGNTTPR;VLLQAS(1)QDENFGNTTPR 185.63 6.1063e-42 2267900.0 19700.3 16333.099999999999 22073.0 20734.5 19007.0 21537.9 17849.8 19028.0 26526.0 21185.7 True False 19419.37010940745 16295.281710452664 20258.243144243992 22259.384298264347 17889.04562919977 20616.77422429712 18773.97530425782 19912.110345129182 23538.36254883669 24847.620016829216 0.7815384369309725 0.6558085522643987 0.8152991365178294 0.8958356688965838 0.7199500643153579 0.829728328521341 0.7555643273497528 0.8013689170891527 0.9473085363062631 1.0 14.600820052087407 -8.317497840663018 2.8370930856612984 0.9976833711213751 0.7793360635456454 0.6217193377984483 0.060706511649634066 0.1742652223906009 2.608671504650399 0.05830605144579328 0.016223003683220577 4.813956475208636e-09 8.317497840663018 -0.21834730757572962 VLLQASQDENFGNT(ph)TPR ddPTM_PC-9_AZD4547_30min_R2 1 VLLQASQDENFGNTTPR 17 0 G3V1T4;P57740 G3V1T4 NUP107 Nuclear pore complex protein Nup107 1 VLLQAS(0.009)QDENFGNT(0.945)T(0.046)PR 94.45 0.0042718999999999995 3354500.0 9622.6 8012.8 11616.0 17863.0 16278.0 12289.0 7694.0 14006.0 12804.0 16709.0 True False 12682.386637486201 10602.780901155755 11461.964250240431 13744.961330598879 14018.08067873281 11520.566887318297 8378.75109474701 11841.694525861616 13480.793300115925 16124.022995823778 0.7865522544076635 0.6575766422500104 0.7108625591274058 0.8524523522547015 0.8693910125508739 0.7144970514059794 0.5196439559108268 0.7344131504233583 0.8360688460694663 1.0 13.976924125401146 -8.571118517672533 2.8378659975456717 0.9990709874827556 0.7293686154340784 0.4413450416004506 0.09375525329345408 0.3016335889977687 6.073881062168544 0.09924759316105963 0.02657166687504081 2.684611723128868e-09 8.571118517672533 -0.2697023720486772 VLLQASQDENFGNTT(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 VLLQASQDENFGNTTPR 17 0 G3V1T4;P57740 G3V1T4 NUP107 Nuclear pore complex protein Nup107 1 VLLQAS(0.001)QDENFGNT(0.144)T(0.855)PR 71.031 0.034035 7657300.0 47614.0 36765.0 38166.0 31157.0 32009.0 34170.0 30463.0 26245.0 39536.0 28081.0 True False 46935.01562866177 36679.872901334886 35028.13880502048 33448.3897167051 30126.293552115283 32708.62875416046 32040.225083396224 27464.438512082997 35083.03934746316 32934.76343441947 1.425090413116826 1.1137129609074854 1.0635612693793715 1.0155952625349316 0.9147262773605015 0.9931338604963934 0.9728390837600983 0.8339042290912726 1.065228217513127 1.0 15.007323567043608 -1.5228787730914395 0.7650461278240462 0.9571907710682319 92.73698951518709 0.8363826981202391 0.06026736741422874 143.67734841891917 0.5813367175530006 0.021209898687932816 22768.444440211042 0.0299999980788772 1.5228787730914395 91.77979874411886 VLLS(ph)DSNLHDA ddPTM_PC-9_AZD4547_30min_R2 2 VLLSDSNLHDA 11 0 H3BV90;Q6FI81-3;Q6FI81;Q6FI81-2 H3BV90 CIAPIN1 Anamorsin 1 VLLS(0.829)DS(0.171)NLHDA;VLLS(0.844)DS(0.156)NLHDA 108.68 0.0021545 7607900.0 22181.0 27948.0 38731.0 56684.0 45567.0 38778.0 33169.0 50258.0 36124.0 45838.0 True False 29234.09660653892 36981.6444470723 38217.401633614165 43616.37955906995 39240.808593673566 36353.20552985829 36120.976743132764 42491.78091394779 38033.44089139234 44233.225572001356 0.660908089529954 0.8360603136860283 0.8639976203273977 0.9860546906775468 0.8871342319315759 0.8218529184737787 0.8166028200755167 0.9606303941090866 0.859838738856672 1.0 15.43284282972304 -4.6817335003782565 1.9050250291954007 0.8951963826475061 0.5442713334338104 0.5821708055391124 0.06099857275682798 0.8165808290745978 2.541236102671663 0.016658862232344834 0.5571924671117674 2.0809732597732227e-05 4.6817335003782565 -0.3509250492136957 VLLS(ph)DSNLHDA ddPTM_PC-9_Lapatinib_30min_R1 1 VLLSDSNLHDA 11 0 H3BV90;Q6FI81-3;Q6FI81;Q6FI81-2 H3BV90 CIAPIN1 Anamorsin 1 VLLS(0.818)DS(0.182)NLHDA 112.94 0.0016255 3372400.0 18707.0 19013.0 21448.0 16656.0 20536.0 22304.0 19638.0 15888.0 20544.0 17273.0 True False 18440.234749556363 18968.97656665524 19684.62823167423 17880.937802787183 19328.11285532942 21350.109913163436 20654.75955052802 16626.214481995597 18230.118382089306 20258.615035174233 0.910241628933632 0.93634123229649 0.971667026472273 0.8826337719405407 0.9540688157492889 1.0538780600793334 1.0195543730243146 0.8206984758399406 0.899869924495681 1.0 14.306247928309277 -1.7451413272649337 23.46591562310675 0.9440463153056478 0.07270522657813572 0.0 0.06625595564563062 0.0 0.0 0.016077857410571827 0.0 0.017982856252942474 1.7451413272649337 -0.871341088727512 VLLSALER ddPTM_PC-9_Lapatinib_30min_R1 2 VLLSALER 8 0 V9GZ78;V9GYY3;A0A384N5Y3;F5H2F4;P11586;A0A494C1T2 V9GZ78 MTHFD1 C-1-tetrahydrofolate synthase, cytoplasmic;Methylenetetrahydrofolate dehydrogenase;Methenyltetrahydrofolate cyclohydrolase;Formyltetrahydrofolate synthetase;C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed 0 ; 94.662 0.030706999999999998 3786300.0 21829.0 23397.0 22518.0 17551.8 21541.0 21950.0 22991.0 19274.0 22604.0 18813.5 False True 21517.714457051676 23342.82568400738 20666.656961993685 18842.617923088394 20274.000731235457 21011.24966794914 24181.36148417302 20169.54040319632 20058.099489327637 22065.38840758702 0.9751795010167584 1.0578932603779194 0.9366097065795411 0.8539445386154861 0.9188145867518196 0.9522265948749209 1.0958955735335454 0.9140804607935735 0.9090299757619861 1.0 14.429497522230118 -5.279038812606608 24.309534339828215 0.945598784003094 1.0165363831981518 0.15747518983507602 0.06367315796773627 944.461040556897 1304553.913909712 0.0177686779405694 0.0371521915881644 5.259702586809136e-06 5.279038812606608 0.07093759919505771 VLNNMEIGTSLFDEEGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLNNMEIGTSLFDEEGAK 18 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 89.46600000000001 0.013153 0.0 4406.8 3871.0 4766.4 3142.8 5605.3 4823.9 4918.1 4949.4 4057.5 1309.7 False True 5152.78420173258 4255.2872974522425 4880.049052672662 2966.7191050950737 4506.981702982728 4570.926192009382 4452.221964039456 4819.483494322775 4116.833261464154 1547.1382424205046 3.330526038624077 2.750424739546756 3.1542424063138683 1.9175526942270062 2.913108589398925 2.954439407339675 2.8777143774003897 3.1150955759342307 2.660934329322343 1.0 10.595386397249824 -8.57074195196566 19.44692059464419 0.9999999959283663 2.855713327907433 0.7084920097426506 0.35869235201950406 810.4553889053633 329290.0282692071 0.34401707243868707 0.08882482616286974 2.686940491181587e-09 8.57074195196566 1.8557133319790666 VLNSYWVGEDSTYK ddPTM_PC-9_Lapatinib_30min_R1 1 VLNSYWVGEDSTYK 14 0 P61313;A0A2R8YEM3;E7EQV9;E7EX53;A0A2R8Y738;E7ENU7 P61313 RPL15 60S ribosomal protein L15;Ribosomal protein L15 0 167.22 0.001861 6945900.0 23432.0 27506.0 32289.0 26898.0 33575.0 30322.0 29261.0 25803.0 24515.0 27661.0 False True 23097.855383097467 27442.311546963592 29634.323059144408 28876.168649097628 31600.184510989737 29025.198744034326 30775.991404827397 27001.90157848267 21753.862545605512 32442.16699403431 0.7119701771877588 0.8458840481281622 0.913450789664999 0.8900813763275301 0.9740466633070657 0.8946750921222889 0.9486416678172793 0.8323088153589729 0.6705428324071497 1.0 14.98558256800515 -4.7900606027778805 2.948120299341603 0.8895150161438039 0.6838412848953541 0.2779824609771676 0.08646055108649549 0.531013737625121 6.690584686921638 0.022573474196169733 0.26075700747598557 1.6215838008160755e-05 4.7900606027778805 -0.2056737312484498 VLNT(ph)GSDVEEAVADALKKPAR ddPTM_PC-9_AZD4547_30min_R2 2 VLNTGSDVEEAVADALKKPAR 21 2 E3W994;J3KR49;O75122 E3W994 CLASP2 CLIP-associating protein 2 1 VLNT(0.691)GS(0.309)DVEEAVADALKKPAR;VLNT(0.605)GS(0.395)DVEEAVADALKKPAR 107.88 2.8479e-05 7246960.0 26278.0 21052.6 39479.0 56951.0 48835.0 41317.0 34251.0 42016.0 37329.0 44237.0 True False 34633.857383644965 27857.441243968602 38955.48266487964 43821.826834178864 42055.10320345966 38733.44145848561 37299.27264702104 35523.392631629395 39302.13473133609 42688.27609469484 0.811320122340315 0.6525782672079052 0.9125569413593841 1.0265541465523107 0.9851675225808926 0.9073554849711835 0.8737591690111953 0.8321580509090675 0.9206774863466654 1.0 15.381552282124403 -5.32880021949705 7.484695403539464 0.9291029825917688 0.7325124892842401 0.5962129380536552 0.06593771499255521 0.18102810129889155 17.875297876009068 0.018406846992233727 0.038688158412465284 4.690290913535866e-06 5.32880021949705 -0.19659049330752876 VLNT(ph)GSDVEEAVADALKKPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VLNTGSDVEEAVADALKKPAR 21 2 E3W994;J3KR49;O75122 E3W994 CLASP2 CLIP-associating protein 2 1 VLNT(0.595)GS(0.405)DVEEAVADALKKPAR;VLNT(0.562)GS(0.438)DVEEAVADALKKPAR 86.617 0.00021255 6462900.0 27090.3 17377.5 27360.1 36467.6 38022.5 39425.0 34323.3 39705.6 40078.5 29550.2 True False 31676.152732185743 19102.623356103424 28012.468547757064 34424.438601554386 30572.26407180005 37357.483596254046 31071.948544827334 38663.37007156069 40664.57224142727 34907.41734074551 0.9074332948491125 0.5472367998364056 0.8024789767262344 0.9861640082256281 0.8758099682188384 1.0701875544556174 0.8901245326035265 1.107597554243323 1.164926406456365 1.0 15.091246001191452 -6.0521959727091375 0.836704042163821 1.058284871194055 0.7044417580392176 0.5118408474281313 0.1173234456235181 0.5515306655941477 0.7879603601636538 0.05736321828072358 0.12645942350317602 8.867557786617827e-07 6.0521959727091375 -0.3538431131548373 VLNT(ph)GSDVEEAVADALKKPAR ddPTM_PC-9_Lapatinib_30min_R1 1 VLNTGSDVEEAVADALKKPAR 21 2 E3W994;J3KR49;O75122 E3W994 CLASP2 CLIP-associating protein 2 1 VLNT(0.596)GS(0.404)DVEEAVADALKKPAR 104.38 4.4458999999999996e-05 5762400.0 21896.0 12529.0 14841.0 15141.0 12654.0 11447.0 9018.2 7168.1 14483.0 6451.2 True False 21583.759024765382 12499.989870279467 13620.8302679167 16254.519648895335 11909.716598721205 10957.438494260306 9485.118269608507 7501.156094435589 12851.772027248813 7566.281324316335 2.8526244398817173 1.6520651736946785 1.8002014046374937 2.148283807087234 1.5740515172818172 1.4481933759250467 1.2536037008200396 0.9913927030876518 1.6985585753923917 1.0 12.885368703350547 -1.5228787452803882 0.252331760811429 1.087554248732517 10.278850460177688 0.6626183494339826 0.30618588408732583 32.27759659327134 0.4405043062420807 0.3937470496834802 126.30219333839011 0.029999999999996498 1.5228787452803882 9.191296211445172 VLNTGS(ph)DVEEAVADALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLNTGSDVEEAVADALK 17 0 E3W994;J3KR49;O75122 E3W994 CLASP2 CLIP-associating protein 2 1 VLNT(0.012)GS(0.988)DVEEAVADALK 233.34 3.3999999999999998e-37 3111100.0 27336.0 32832.0 25656.0 29230.0 33167.0 23162.0 25047.0 26065.0 22793.0 19119.0 True False 31963.444889389528 36091.343980871075 26267.73634092184 27592.337864938603 26668.164441301662 21947.343945629327 22674.36683542346 25380.821368150308 23126.30450488047 22585.123354079285 1.4152433169516583 1.598014029635677 1.163054809535827 1.2217041028449784 1.1807845378221016 0.9717610836810079 1.0039514276696682 1.1237849344562498 1.0239618417095533 1.0 14.463085172972098 -5.541490657955639 0.9242409227258006 1.0376498463370134 1.5633052678755892 0.7754154752237193 0.09059014746302978 0.386542977896384 0.5333903240486865 0.03518867139459232 0.1624554085892844 2.8741494183530735e-06 5.541490657955639 0.5256554215385758 VLNTGS(ph)DVEEAVADALK ddPTM_PC-9_Lapatinib_30min_R1 1 VLNTGSDVEEAVADALK 17 0 E3W994;J3KR49;O75122 E3W994 CLASP2 CLIP-associating protein 2 1 VLNT(0.109)GS(0.891)DVEEAVADALK 77.64399999999999 0.0075462 1653300.0 5189.3 7193.9 5714.4 5634.9 7086.4 6518.8 7503.2 6374.0 7620.5 6449.3 True False 5115.299630398927 7177.242966541896 5244.584090221899 6049.309343475354 6669.591884398447 6240.006120065001 7891.678982560437 6670.159309431014 6762.199042577471 7564.052911847923 0.6762643902697453 0.9488620783310295 0.6933563463057042 0.7997444510204369 0.8817484438734636 0.824955376804807 1.0433135614637676 0.8818234598786634 0.8939915044731547 1.0 12.8849437398844 -6.722799652342474 1.4558335631390997 0.9414750851215411 0.7869783152250529 0.41146944741696745 0.08726685747136888 0.43059386117913834 1.902363909090179 0.03770241912243507 0.03527528184777453 1.8932167913177972e-07 6.722799652342474 -0.1544967698964882 VLPCGPS(ph)PQHHR ddPTM_PC-9_AZD4547_30min_R2 1 VLPCGPSPQHHR 12 0 P98174 P98174 FGD1 FYVE, RhoGEF and PH domain-containing protein 1 1 VLPCGPS(1)PQHHR 78.69 0.0091807 4141400.0 33916.0 18339.0 32442.0 56831.0 45255.0 32083.0 32828.0 32720.0 25777.0 32211.0 True False 44700.58250337556 24266.723111308816 32011.79788277375 43729.490980197304 38972.124408161515 30076.844938223818 35749.62840373731 27663.8758308005 27139.519595211503 31083.302694265334 1.4380898626844607 0.7806996363930744 1.0298711883238751 1.4068482815458703 1.2537961230018075 0.9676206300874456 1.150123227102662 0.8899915206212725 0.8731221344834301 1.0 14.923852182120461 -7.760441633560972 24.99892548022081 0.9111675754904235 1.1353839678147384 0.2298312789138146 0.18826257557930265 41.494634631482754 1039761.9988246204 0.09643308019595724 0.05154261873829055 1.7360345592889372e-08 7.760441633560972 0.2242163923243149 VLPITVPKS(ph)PAFALK ddPTM_PC-9_AZD4547_30min_R2 1 VLPITVPKSPAFALK 15 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 VLPIT(0.004)VPKS(0.996)PAFALK 55.196000000000005 0.033669 6632500.0 39167.0 13409.0 39050.0 145290.0 105350.0 47423.0 38364.0 53099.0 34387.0 75560.0 True False 51621.29127579049 17743.19702271334 38532.17148518329 111795.63520812352 90723.97097336914 44457.632313230984 41778.321679084256 44893.769643633146 36204.62661754815 72914.66739867408 0.7079685489552024 0.24334194553338923 0.5284556984193824 1.5332393220264005 1.2442485745332896 0.6097213893900232 0.5729755503190291 0.6157028653531171 0.49653420785138924 1.0 16.153921433537498 -5.548563334952913 24.999945047498866 0.8585234358391085 0.45321524024928844 0.2163365900481683 0.3265616572619973 342.7502820914083 333612.38234643947 0.09818525628265629 0.17006856348288069 2.8277217026748864e-06 5.548563334952913 -0.40530819558982006 VLPITVPKS(ph)PAFALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLPITVPKSPAFALK 15 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 VLPIT(0.001)VPKS(0.999)PAFALK 64.454 0.016944999999999998 4908900.0 28116.0 3269.5 15614.0 37724.0 42952.0 47027.0 30102.0 68605.0 44350.0 26220.0 True False 32875.48348368731 3594.074352627255 15986.29697642475 35610.446582858145 34535.86393351188 44560.82133369789 27250.52064039275 66804.19144300591 44998.5348480432 30973.478442594205 1.0614075375685768 0.11603715608785949 0.516128564831797 1.1497076974695635 1.1150140594483162 1.438676686452452 0.8798017533257839 2.1568191498678404 1.4528085675440952 1.0 14.918745791947915 -6.016806564867232 1.6027000682007615 1.4114283764666269 0.5089170460394895 0.4250644017754366 0.3959254697180935 0.33864816885047233 1.7533309348508725 0.1351059864239016 0.22634749603220108 9.620406767102863e-07 6.016806564867232 -0.9025113304271374 VLPPPAGYVPIRT(ph)PAR ddPTM_PC-9_AZD4547_30min_R2 2 VLPPPAGYVPIRTPAR 16 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 VLPPPAGYVPIRT(1)PAR;VLPPPAGYVPIRT(1)PAR 91.926 0.0022702 107983000.0 203460.0 186771.0 239380.0 310600.0 268870.0 278670.0 191995.0 246740.0 206965.0 262140.0 True False 268156.04776910035 247141.07324402954 236205.66479188684 238995.96872216364 231542.04153402746 261244.72084701605 209082.18305640097 208612.0025211406 217904.74737257816 252962.55838920674 1.060062206346431 0.9769867715513049 0.933757415706012 0.9447879174057285 0.9153213938395508 1.032740665300619 0.8265341099796608 0.8246754138221964 0.8614110671560776 1.0 17.948564338314505 -7.26959312698081 24.97330880436026 0.863544763923286 0.9709919373263298 0.36898260351664225 0.06201599080287858 614.5106527930245 1882115.7712328047 0.025201317304066415 0.017310782454752458 5.375351555957409e-08 7.26959312698081 0.10744717340304377 VLPPPAGYVPIRT(ph)PAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VLPPPAGYVPIRTPAR 16 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 VLPPPAGY(0.017)VPIRT(0.983)PAR;VLPPPAGYVPIRT(1)PAR 126.04 2.1335e-05 84380000.0 233201.0 219093.0 250650.0 279460.0 274305.0 272778.0 249630.0 225645.0 205270.0 176476.0 True False 272677.3233703002 240843.105104806 256626.4465954188 263802.76222154393 220556.90436491836 258473.04148177552 225983.23923530834 219722.05784063955 208271.6854173129 208469.7018167522 1.3079949795773553 1.1552906873561437 1.2310011687981262 1.2654249510724118 1.0579806199310007 1.2398590261762688 1.084009989297873 1.0539759779278541 0.9990501430293531 1.0 17.669478197603333 -7.40149195036778 0.6441311157601038 0.9820792103111271 1.235067290235875 0.6659930076723146 0.06308923112363157 0.45653464480647854 0.37648630599475924 0.05527456471927231 0.03530095756749322 3.967418824596787e-08 7.40149195036778 0.2529880799247479 VLPPPAGYVPIRT(ph)PAR ddPTM_PC-9_Lapatinib_30min_R1 2 VLPPPAGYVPIRTPAR 16 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 VLPPPAGY(0.001)VPIRT(0.999)PAR;VLPPPAGY(0.001)VPIRT(0.999)PAR 102.5 0.0010756 79776000.0 213640.0 209110.0 230940.0 194838.0 214290.0 228140.0 173436.0 176298.0 221420.0 159170.0 True False 210593.45442322214 208625.81864268042 211953.0046541795 209167.03648051425 201685.88351034964 218382.9840203151 182415.66745113468 184489.448687491 196481.3479440329 186682.32241930693 1.1280846075516913 1.1175445855772366 1.1353673015600916 1.1204437237003322 1.0803694795340248 1.1698107308189865 0.9771448366782747 0.9882534473355731 1.0524903772233793 1.0 17.51022579479438 -7.267406273510664 24.999894779578444 1.0034932815190358 1.1231175631903172 0.8223244797304947 0.027495457924609144 195.85125762894447 820567.4332369629 0.011037762900219444 0.007650163753021326 5.402486949933401e-08 7.267406273510664 0.11962428167128136 VLPPPAGYVPIRT(ph)PARK ddPTM_PC-9_AZD4547_30min_R2 1 VLPPPAGYVPIRTPARK 17 2 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 VLPPPAGYVPIRT(1)PARK 63.16 0.01247 11623000.0 48754.0 48627.0 61512.0 95317.0 80420.0 80494.0 53827.0 70513.0 60930.0 62263.0 True False 64256.75785380274 64344.72679718711 60696.31068877321 73343.13828297007 69255.0711502454 75460.69745526867 58617.49872328405 59616.836077543856 64150.635408939685 60083.19132138227 1.069463130047408 1.0709272490705442 1.0102045073490087 1.2206931201550355 1.1526530070582164 1.255936906740403 0.9756056133859752 0.9922381745446259 1.0676968715892743 1.0 15.874673823248111 -7.300684756907313 24.995624459045576 1.0082383236620571 1.127005152550399 0.407547324245751 0.07147094606993143 621.0632649316179 395556.5970408006 0.0321844502524166 0.021699311607497586 5.0039762883222715e-08 7.300684756907313 0.11876682888834189 VLPPPAGYVPIRT(ph)PARK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLPPPAGYVPIRTPARK 17 2 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 VLPPPAGYVPIRT(1)PARK 56.568999999999996 0.022872 12014000.0 34396.0 25329.0 34173.0 38856.0 37709.0 41455.0 41859.0 36320.0 29830.0 26433.0 True False 40218.56344803348 27843.495726470646 34987.81392182419 36679.02429285169 30320.19214632147 39281.026822643325 37893.812487083946 35366.63848422098 30266.207317184406 31225.093656487123 1.288020586598879 0.8917025528500236 1.120503089813963 1.1746649888824752 0.9710200545714727 1.257995484490166 1.2135692178848396 1.1326351450950232 0.9692911621066186 1.0 14.930418278605961 -8.259216382251775 24.097553465417665 0.9846455653050791 1.1259929626447576 0.20420778711199872 0.11539954866345592 186.2092969087612 2018630.248384245 0.08600388953981573 0.028912401423701536 5.505333311342429e-09 8.259216382251775 0.1413473973396785 VLPPPAGYVPIRT(ph)PARK ddPTM_PC-9_Lapatinib_30min_R1 2 VLPPPAGYVPIRTPARK 17 2 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 VLPPPAGYVPIRT(1)PARK;VLPPPAGYVPIRT(1)PARK 72.681 0.0055175 17160000.0 156530.0 107875.0 127346.0 121263.0 123803.0 112101.0 94997.0 81421.0 128969.0 73076.0 True False 154297.85349591344 107625.2220653204 116876.10344977562 130181.08554150938 116521.15094606284 107306.70155019435 99915.4798361091 85204.11690197408 114443.1531162227 85707.08923235055 1.8002927748206967 1.2557330207953992 1.363669032475556 1.5189068571514608 1.3595275722195612 1.2520166360951495 1.165778475631576 0.9941314967655368 1.3352822285910229 1.0 16.387126920845894 -6.849048130272284 1.4809422473264748 1.1169261098461034 1.4639902548339407 0.5138182367249136 0.1578787226113264 0.3473193043165926 1.5785554898965766 0.0724122861959823 0.06092453442661132 1.4156368846540314e-07 6.849048130272284 0.34706414498783733 VLPQPTNLAT(ph)PNTKR ddPTM_PC-9_AZD4547_30min_R2 1 VLPQPTNLATPNTKR 15 1 A0A2R8Y6S3;C9J167;P54278 A0A2R8Y6S3 PMS2 Mismatch repair endonuclease PMS2 1 VLPQPTNLAT(0.983)PNT(0.017)KR 84.375 0.017863 0.0 60570.0 42971.0 32816.0 48760.0 56125.0 38794.0 39247.0 44617.0 37655.0 37950.0 True False 79830.00006573484 56860.53540629542 32380.83839840651 37519.13533449036 48333.01253801932 36368.20504732899 42739.906968486604 37722.4678466634 39645.366425793916 36621.38205108102 2.179874040646108 1.552659463451816 0.8842057995856185 1.0245144566678865 1.3198030721670317 0.9930866343766359 1.1670752051047995 1.0300667460896626 1.0825742832560201 1.0 15.160398617451957 -4.917479990479497 2.8096266562574845 1.0743178556741535 2.2350899239616395 0.9006983454268053 0.115804098903417 0.09159831641395912 1.2238932820944681 0.030263578831607425 0.21413988859662017 1.2092608966911544e-05 4.917479990479497 1.160772068287486 up VLPQPTNLAT(ph)PNTKR ddPTM_PC-9_Lapatinib_30min_R1 1 VLPQPTNLATPNTKR 15 1 A0A2R8Y6S3;C9J167;P54278 A0A2R8Y6S3 PMS2 Mismatch repair endonuclease PMS2 1 VLPQPTNLAT(0.936)PNT(0.064)KR 69.258 0.022175999999999998 7724400.0 54711.0 31531.0 36955.0 41829.0 34525.0 34441.0 22525.0 21771.0 31306.0 21147.0 True False 53930.81110723141 31457.991906758856 33916.702550425274 44905.244197453474 32494.307378761605 32968.0387158923 23691.234284328537 22782.56013894298 27779.988613205205 24802.230773393723 2.1744338886276715 1.268353326528395 1.3674859677061382 1.8105324721687939 1.3101364823046264 1.3292368342632446 0.9552057837371228 0.9185689927287782 1.1200600811684178 1.0 14.598182265523539 -6.8414745868488485 1.4514127787661149 0.9871996084802968 1.6075934527908835 0.567862137182271 0.2470258348216133 0.3140437288642765 1.3731627337249432 0.11591540717804186 0.09799011976651438 1.4405403023543691e-07 6.8414745868488485 0.6203938443105868 VLPQPTNLATPNT(ph)KR ddPTM_PC-9_AZD4547_30min_R2 1 VLPQPTNLATPNTKR 15 1 A0A2R8Y6S3;C9J167;P54278 A0A2R8Y6S3 PMS2 Mismatch repair endonuclease PMS2 1 VLPQPTNLAT(0.292)PNT(0.708)KR 71.929 0.017553 18675000.0 105030.0 79434.0 88390.0 119270.0 115250.0 94534.0 95462.0 87504.0 64440.0 86821.0 True False 138427.3552402862 105109.48708346723 87217.89084699996 91774.14420313106 99249.52685980801 88622.77403578382 103957.93306560144 73982.26744188182 67846.16684313251 83781.42321625559 1.6522440169460861 1.2545679346143346 1.0410170596156407 1.095399680263783 1.1846245032580356 1.0577854926984447 1.2408231929561102 0.883039038987434 0.8097996457759952 1.0 16.354342771388097 -1.5892717795060296 0.853625219919135 1.0322069218279342 199.99912839469334 0.7118165951725365 0.11975198190329255 351.2299508105659 1.0932952574424841 0.044236771871417176 135552.41885275012 0.025747094113368413 1.5892717795060296 198.9669214728654 VLPQPTNLATPNT(ph)KR ddPTM_PC-9_Lapatinib_30min_R1 1 VLPQPTNLATPNTKR 15 1 A0A2R8Y6S3;C9J167;P54278 A0A2R8Y6S3 PMS2 Mismatch repair endonuclease PMS2 1 VLPQPTNLAT(0.213)PNT(0.787)KR 69.111 0.022430000000000002 8731400.0 48364.0 38856.0 44916.0 42960.0 33191.0 31256.0 37270.0 24373.0 40421.0 27440.0 True False 47674.32049112862 38766.03131930555 41223.17986077398 46119.42171035887 31238.770636016703 29919.253741294673 39199.65823648942 25505.458558011007 35868.361328000006 32182.967438498297 1.4813525378675638 1.2045511773700637 1.28090052415308 1.433038199429346 0.9706615990496851 0.9296611258259642 1.2180249789395596 0.7925141958009926 1.1145137997776153 1.0 14.974009735798168 -6.2686793439716295 24.87545983881485 1.0008163565780688 1.3346413607869845 0.640446153265392 0.1266835391682061 334.4678766280942 1149180.8871306106 0.03746607220128142 0.043367612692738 5.386673541914572e-07 6.2686793439716295 0.3338250042089157 VLPSFWIPSLT(ph)PEAK ddPTM_PC-9_Lapatinib_30min_R1 1 VLPSFWIPSLTPEAK 15 0 A0A075B797;M0R3B2;Q9Y314;A0A075B6F9 A0A075B797 NOSIP Nitric oxide synthase-interacting protein 1 VLPS(0.095)FWIPS(0.444)LT(0.461)PEAK 121.95 0.00072233 0.0 4211.3 3930.1 2848.8 2260.5 2847.3 3470.7 2454.3 3127.2 2965.6 2410.9 True False 4151.246089742163 3921.0000949146247 2614.58266068601 2426.7447108069423 2679.827412007181 3322.2662515968577 2581.371645017872 3272.5011284048755 2631.58289884755 2827.6208526776786 1.4681056287341523 1.386678164861299 0.9246581479302901 0.8582284674088757 0.9477322284808654 1.174933424490332 0.9129129326420778 1.1573337794937775 0.930670353613892 1.0 11.46537297106384 -5.209288887452913 5.579943723822242 0.9918028344015422 1.438827363872825 0.7596828265127633 0.09889193042630443 0.09850303454748727 7.032086730933863 0.02588650326824608 0.07019015809757069 6.176054397787875e-06 5.209288887452913 0.4470245294712829 VLPSISLS(ph)PGPQPPK ddPTM_PC-9_AZD4547_30min_R2 2 VLPSISLSPGPQPPK 15 0 Q99638 Q99638 RAD9A Cell cycle checkpoint control protein RAD9A 1 VLPSIS(0.04)LS(0.96)PGPQPPK;VLPSIS(0.056)LS(0.944)PGPQPPK 168.5 0.00020143 6827100.0 35280.0 40266.0 46552.0 32554.0 34747.0 47462.0 44280.0 53200.0 42287.0 37321.0 True False 46498.30613041309 53281.197055453486 45934.69006346353 25049.17825428628 29922.978826878552 44494.19363706571 48220.83421827363 44979.16241438224 44522.20448937848 36014.40314962832 1.2911030605512885 1.4794413455663047 1.275453319957007 0.695532233318291 0.8308614390347704 1.235455532949042 1.3389319272606433 1.2489215003094238 1.236233301004683 1.0 15.136286374906367 -5.532138614268894 24.997176862775834 1.0916524498010134 1.3833160831716598 0.290543238113086 0.19455855155914475 268.2721726650184 724203.0560652781 0.0598954062322622 0.10391599784180207 2.9367121885596672e-06 5.532138614268894 0.2916636333706464 VLPSISLS(ph)PGPQPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VLPSISLSPGPQPPK 15 0 Q99638 Q99638 RAD9A Cell cycle checkpoint control protein RAD9A 1 VLPSIS(0.028)LS(0.972)PGPQPPK;VLPSIS(0.024)LS(0.976)PGPQPPK 154.72 9.3212e-11 2945000.0 43483.0 63489.0 44219.0 42739.0 44126.0 31455.0 44439.0 21444.7 23812.0 29345.0 True False 50843.81307160249 69791.76833581644 45273.34866149136 40344.472391707524 35479.82706114141 29805.444426637212 40229.41620950148 20881.799347537813 24160.20545212187 34665.01620510781 1.466718283665789 2.013319939701421 1.3060241597354407 1.1638382671738912 1.0235052783824616 0.8598133706409591 1.1605191808210888 0.6023882759489646 0.6969621854254873 1.0 15.081192814503474 -5.766309493783317 1.1775191712975204 0.8573979319093306 1.7706869670890653 0.7179390503640479 0.20526820293458276 0.2695326767871022 0.7307218132873765 0.07373402291152453 0.19677059459113128 1.7127363153327123e-06 5.766309493783317 0.9132890351797347 VLPSISLS(ph)PGPQPPK ddPTM_PC-9_Lapatinib_30min_R1 1 VLPSISLSPGPQPPK 15 0 Q99638 Q99638 RAD9A Cell cycle checkpoint control protein RAD9A 1 VLPSIS(0.028)LS(0.972)PGPQPPK 196.37 1.0553e-09 2569300.0 13977.0 22387.0 19139.0 17593.0 18208.0 17450.0 20700.0 19517.0 19798.0 17251.0 True False 13777.68541693212 22335.164276953165 17565.46529867649 18886.847908527558 17137.041238305323 16703.704177936776 21771.744714122116 20423.831070311444 17568.140757817582 20232.812364487396 0.6809575045095903 1.103908041778503 0.8681672612902479 0.9334761558742929 0.846992545059343 0.825575005442896 1.0760612178826832 1.0094410357978372 0.8682994949655718 1.0 14.304409248249279 -7.252786941485813 24.90329440329408 0.9892371917942163 0.8877169821260839 0.19611078161372664 0.10962328016615183 1104.1549845409181 3177964.3973275037 0.040983231366809994 0.03125025818735261 5.5874423925325745e-08 7.252786941485813 -0.10152020966813247 VLQATVVAVGS(ph)GSK ddPTM_PC-9_AZD4547_30min_R2 1 VLQATVVAVGSGSK 14 0 P61604;B8ZZL8;S4R3N1 P61604 HSPE1;HSPE1-MOB4 10 kDa heat shock protein, mitochondrial 1 VLQATVVAVGS(0.974)GS(0.026)K 163.9 0.00054603 4593900.0 28203.0 24661.0 28489.0 38500.0 34867.0 32334.0 23766.0 29910.0 27533.0 26029.0 True False 37170.96734115761 32632.185977860652 28111.21724561809 29624.41981907054 30026.318898229318 30312.149868545002 25881.12795915743 25288.096763424288 28988.338170266445 25117.732632611 1.4798695361896472 1.2991692544530649 1.1191781382815011 1.179422531976807 1.1954231433790075 1.2068027919522464 1.0303926846309086 1.0067826237863564 1.154098524507349 1.0 14.616418618168924 -1.5228787452803376 0.4422280254744123 1.0725765637974782 9.515392620914497 0.7592107242380816 0.06809568170411119 44.829685829936466 0.5493166298105328 0.046575718252001484 340.03572575567875 0.029999999999999995 1.5228787452803376 8.44281605711702 VLQATVVAVGS(ph)GSK ddPTM_PC-9_Lapatinib_30min_R1 1 VLQATVVAVGSGSK 14 0 P61604;B8ZZL8;S4R3N1 P61604 HSPE1;HSPE1-MOB4 10 kDa heat shock protein, mitochondrial 1 VLQATVVAVGS(0.893)GS(0.107)K 85.36200000000001 0.030272000000000004 0.0 15190.0 12644.0 13241.0 9978.6 12910.0 11143.0 9354.0 11338.0 12309.0 9869.0 True False 14973.387814495163 12614.72359484504 12152.376091738093 10712.459531633778 12150.659182036561 10666.439865601697 9838.304350526492 11864.804871403958 10922.630800483712 11574.843500384102 1.2936147096933348 1.0898396677610742 1.0498954989183937 0.9254949780770939 1.0497471677810029 0.9215191432391927 0.8499729910127957 1.0250509971050783 0.9436525686175586 1.0 13.498705066966183 -3.2130763791181662 0.7392813972931623 0.9523048479404832 4.4599321062762876 0.7656577577319654 0.056256954263600355 10.924912658752067 0.7047792004787228 0.021305344148484385 52.772782870042676 0.000612242707486674 3.2130763791181662 3.5076272583358046 VLQLYPNNK ddPTM_PC-9_Lapatinib_30min_R1 2 VLQLYPNNK 9 0 Q02790;H0YFG2 Q02790 FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed 0 ; 101.28 0.016347 5679800.0 75835.0 81241.0 71116.0 71770.0 66220.0 61607.0 69403.0 64183.0 67425.0 65202.0 False True 74753.57899356425 81052.891455932 65269.11699569858 77048.20521770134 62325.06979352922 58972.21222293131 72996.34774851288 67165.17649156108 59830.88648327351 76472.0788237961 0.9775277479484827 1.0599017667963602 0.8535025855134535 1.0075338136842433 0.8150042571372508 0.7711600512235678 0.9545490180371341 0.8782967263950074 0.7823886496028629 1.0 16.222645472514166 -5.518603634728845 1.2265644780360265 0.8673162247679719 1.0218127769189387 0.24917235267106808 0.08463851841386005 0.7604386556921172 2.0245436048751304 0.027793914013707687 0.10713550220696798 3.029677246360983e-06 5.518603634728845 0.1544965521509668 VLQSFTVDSSK ddPTM_PC-9_Lapatinib_30min_R1 2 VLQSFTVDSSK 11 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 155.97 0.0032384000000000002 10441300.0 72028.0 59719.0 65811.0 60541.0 62553.0 56753.0 68505.0 57799.0 61935.0 62408.0 False True 71000.86751168253 59580.72432462444 60400.27361780645 64993.3870988556 58873.75552392976 54325.80648770468 72051.85370246063 60484.55254562338 54959.22809553651 73195.1396465672 0.9700216142017077 0.8139983694589308 0.8251951415006171 0.8879467600264869 0.804339684413607 0.7422051074705822 0.9843803024404751 0.8263465694263493 0.7508589827263764 1.0 16.15946023242219 -11.376875496219036 7.077141937689106 1.0144373508353826 0.8441261626391896 0.26576025567622075 0.07726121071673045 0.01782738295642001 0.00036778305695656777 0.07577500791532688 0.017747872840230012 4.198793379781841e-12 11.376875496219036 -0.17031118819619295 VLS(ph)GPGSAR ddPTM_PC-9_AZD4547_30min_R2 3 VLSGPGSAR 9 0 B0QYC3;B0QYC4;Q9BWT7-2;Q9BWT7 B0QYC3 CARD10 Caspase recruitment domain-containing protein 10 1 VLS(1)GPGSAR;VLS(0.998)GPGS(0.002)AR;VLS(0.977)GPGS(0.023)AR 89.029 0.0096617 25265000.0 57541.0 55581.0 78592.0 105002.0 79625.0 84617.0 67172.0 90883.0 67219.0 64127.0 True False 75837.84107284856 73546.47130430542 77549.8187288994 80795.41116472839 68570.44317754645 79325.88561349278 73150.17787059362 76839.12063357713 70772.05910969178 61881.933248739726 1.225524754826451 1.1884966652331155 1.2531899806229592 1.30563812284216 1.1080850189654172 1.2818908758819088 1.182092640457114 1.2417052376937823 1.1436627040273197 1.0 15.917230648165782 -8.614666483803882 2.7113279669122416 1.0000994618487264 1.222603742945619 0.6274260148883517 0.05274645509715624 0.2402401486990526 4.049068462051169 0.04821616048653495 0.012946487043264966 2.428474324626408e-09 8.614666483803882 0.22250428109689246 VLS(ph)GPGSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VLSGPGSAR 9 0 B0QYC3;B0QYC4;Q9BWT7-2;Q9BWT7 B0QYC3 CARD10 Caspase recruitment domain-containing protein 10 1 VLS(1)GPGSAR;VLS(0.996)GPGS(0.004)AR 86.882 0.01132 13130200.0 37614.0 48445.0 45031.0 34515.0 50849.0 32975.0 42628.0 27987.0 29634.0 26228.0 True False 43981.30728963631 53254.29943814877 46104.7098210185 32581.236449139804 40885.5034726007 31245.732950830126 38589.96724000607 27252.370904677668 30067.34118797998 30982.928779266236 1.4195335632397859 1.7188271585798736 1.48806816003372 1.0515867199405355 1.3196138997666762 1.0084822249515597 1.245523543462762 0.8795931171915208 0.9704486429346547 1.0 14.919185906362825 -5.877908681802763 0.7328774839489454 0.9991162309497481 1.65604656289617 0.6698022010542036 0.14871288452837364 0.5473622097224629 0.5437080952466836 0.07771261076007517 0.23616860964481995 1.3246200310125532e-06 5.877908681802763 0.6569303319464219 VLS(ph)GPGSAR ddPTM_PC-9_Lapatinib_30min_R1 3 VLSGPGSAR 9 0 B0QYC3;B0QYC4;Q9BWT7-2;Q9BWT7 B0QYC3 CARD10 Caspase recruitment domain-containing protein 10 1 VLS(0.999)GPGS(0.001)AR;VLS(0.999)GPGS(0.001)AR;VLS(1)GPGSAR 84.81700000000001 0.012915000000000001 29073900.0 71965.0 89072.0 85885.0 59619.0 87066.0 79353.0 87535.0 91685.0 89211.0 99441.0 True False 70938.7659032352 88865.7592565675 78823.86682568729 64003.58014315381 81944.9490583421 75959.25717087786 92067.13398795563 95945.0198125481 79163.11774652309 116629.24435319625 0.6082416661159745 0.761950913335675 0.67584993166019 0.5487781430644224 0.7026106489225177 0.6512882561499351 0.789400072842301 0.8226497594547667 0.6787587297298099 1.0 16.831570058801198 -9.858940197876294 0.2932118431200906 1.1128948291466059 0.6406415027851445 0.6475232534224984 0.07169683309547868 5.166240527093792 0.5450781907757097 0.685882483003178 0.09311043371812866 1.3837569084583446e-10 9.858940197876294 -0.47225332636146133 VLS(ph)PEELEDR ddPTM_PC-9_AZD4547_30min_R2 3 VLSPEELEDR 10 0 A0A494C179;A0A0A0MRH8;A0A494C1P7;A0A0A0MSH9;A0A494C1F7;Q86WJ1-5;Q86WJ1-3;Q86WJ1-4;Q86WJ1-2;Q86WJ1 A0A494C179 CHD1L Chromodomain-helicase-DNA-binding protein 1-like 1 VLS(1)PEELEDR;VLS(1)PEELEDR;VLS(1)PEELEDR 98.75399999999999 0.006852800000000001 5176600.0 32111.3 33378.200000000004 37155.5 41629.1 37696.6 36470.2 26701.2 37970.8 33045.1 31778.6 True False 42322.025443467486 44167.05040372367 36662.79379302759 32032.154158183628 32463.077780680607 34189.71262868217 29077.555072921616 32103.285342180934 34791.79652309129 30666.04088665305 1.3800942090926231 1.4402592942131873 1.195550280798867 1.044548080940085 1.0586002249416453 1.1149046841440413 0.94820049253822 1.046867623402714 1.1345382552540035 1.0 14.904354300250104 -5.4668327513826664 2.734817161759568 1.0504102297694085 1.4129082361942678 0.8805767687665971 0.05266062609378944 0.083591849425972 1.2205180808780063 0.014803435248578004 0.0350135276629786 3.4132433173961862e-06 5.4668327513826664 0.3624980064248593 VLS(ph)PEELEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VLSPEELEDR 10 0 A0A494C179;A0A0A0MRH8;A0A494C1P7;A0A0A0MSH9;A0A494C1F7;Q86WJ1-5;Q86WJ1-3;Q86WJ1-4;Q86WJ1-2;Q86WJ1 A0A494C179 CHD1L Chromodomain-helicase-DNA-binding protein 1-like 1 VLS(1)PEELEDR;VLS(1)PEELEDR 91.31299999999999 0.008151 5177100.0 29782.7 31767.0 29230.6 34583.9 39443.0 34821.8 34144.9 30888.0 30286.9 26307.8 True False 34824.32287486178 34920.61781921088 29927.568361667825 32646.276205516595 31714.427293944635 32995.68350772453 30910.447884331494 30077.222728541215 30729.788615314545 31077.195887569796 1.1205748099297064 1.1236733824231022 0.9630073597997367 1.0504897650233107 1.0205047909946636 1.0617329706031193 0.9946343935327512 0.9678229283412102 0.9888211512546984 1.0 14.923568714002776 -1.5228787453666859 0.4707241316919122 0.9967065577768225 4.674194285043466 0.5546756664484254 0.0369678625394716 72.59437400127838 0.8327888043345467 0.0225009693562448 259.8456708137263 0.02999999999403527 1.5228787453666859 3.6774877272666435 VLS(ph)PEELEDR ddPTM_PC-9_Lapatinib_30min_R1 2 VLSPEELEDR 10 0 A0A494C179;A0A0A0MRH8;A0A494C1P7;A0A0A0MSH9;A0A494C1F7;Q86WJ1-5;Q86WJ1-3;Q86WJ1-4;Q86WJ1-2;Q86WJ1 A0A494C179 CHD1L Chromodomain-helicase-DNA-binding protein 1-like 1 VLS(1)PEELEDR;VLS(1)PEELEDR 110.08 0.0017916 1980830.0 12306.0 10018.5 13438.099999999999 10830.4 11581.3 11218.2 11555.7 10834.1 12664.599999999999 9494.7 True False 12130.514183355988 9995.302778784808 12333.27129056609 11626.903745155285 10900.110703711862 10738.423736901465 12153.997603525657 11337.491837826565 11238.179383849703 11135.846244107499 1.0893212709159679 0.8975790936475792 1.1075288774835774 1.0440970080120877 0.9788309271493062 0.9643114229045386 1.0914300841713678 1.018107792555574 1.0091895252052672 1.0 13.442923576273028 -8.413232769638208 3.417935798251457 1.0008585084934942 1.021837334664146 0.01565435785540359 0.06152326956339787 1.5483276052270065 32.53943916394493 0.057041009937472575 0.015173290433460891 3.8615995069676225e-09 8.413232769638208 0.020978826170651832 VLS(ph)PESLSCTEIPIPLNER ddPTM_PC-9_AZD4547_30min_R2 3 VLSPESLSCTEIPIPLNER 19 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 VLS(0.822)PES(0.166)LS(0.008)CT(0.004)EIPIPLNER;VLS(0.982)PES(0.018)LSCTEIPIPLNER;VLS(0.908)PES(0.088)LS(0.003)CT(0.001)EIPIPLNER 220.42 3.3012999999999997e-28 18802200.0 32054.5 29487.4 55851.7 63927.7 57696.9 50784.9 38314.5 57404.1 42991.1 51677.6 True False 42247.16422498091 39018.62539246457 55111.069965147515 49190.15643811937 49686.68135598839 47609.312174771796 41724.41627497847 48533.61535998944 45263.52177792987 49868.38295343723 0.8471733335413673 0.7824321359867791 1.1051304794985122 0.986399668985635 0.9963563767925161 0.9546993376389454 0.8366907808889072 0.9732341913975018 0.9076597053526484 1.0 15.605837802065604 -5.2303149988668105 24.998353959812075 0.9652818772634163 0.8148026879288529 0.46411810006598553 0.0665593793930189 633.6391231947703 508921.80746187037 0.017593372163633308 0.04653814078351574 5.884167150169439e-06 5.2303149988668105 -0.1504791893345634 VLS(ph)PESLSCTEIPIPLNER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VLSPESLSCTEIPIPLNER 19 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 VLS(0.999)PES(0.001)LSCTEIPIPLNER;VLS(1)PESLSCTEIPIPLNER;VLS(0.993)PES(0.007)LSCTEIPIPLNER;VLS(0.875)PES(0.123)LS(0.002)CTEIPIPLNER 281.49 1.0357999999999998e-92 18246700.0 32141.0 26148.09 33024.8 34931.5 42072.6 42575.5 43138.2 46367.0 39658.1 34165.5 True False 37581.83648631362 28743.899568493423 33812.23647925144 32974.40130445102 33828.77605068618 40342.76583011577 39051.83740247794 45149.91537989742 40238.02468674592 40359.43469605082 0.931178465936021 0.7121977744476689 0.8377777521883868 0.817018413483318 0.8381875590045451 0.9995869896082396 0.9676011989905094 1.1186954356502756 0.9969917812224268 1.0 15.30061834668659 -6.794548140283792 2.330445207047694 1.029944474519058 0.8156430356279172 0.6971667490919342 0.062195491852800405 0.1543824226923622 1.719625549783276 0.02321732782670623 0.020996895139252337 1.6049143481357003e-07 6.794548140283792 -0.21430143889114084 VLS(ph)PESLSCTEIPIPLNER ddPTM_PC-9_Lapatinib_30min_R1 2 VLSPESLSCTEIPIPLNER 19 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 VLS(1)PESLSCTEIPIPLNER;VLS(0.591)PES(0.409)LSCTEIPIPLNER 174.87 1.3364e-08 13000700.0 22386.1 20558.3 25773.2 22125.8 29513.0 27419.7 26323.8 26385.0 33285.0 26183.3 True False 22066.870108892035 20510.698519448182 23654.226983429067 23753.005141505084 27777.103364790473 26247.0233494426 27686.71756065738 27610.943423178134 29536.092793411335 30709.04851794579 0.7185787633894476 0.6679040709275677 0.7702689638725205 0.7734855453963113 0.9045250408379816 0.8546999863608387 0.9015817453438124 0.8991142596633308 0.9618042309630986 1.0 14.906376192426357 -5.549394805521815 0.3061481721385461 0.9981489367998332 0.524245680222875 0.9027071825110117 0.03203495482530441 1.329776414466802 0.14654728559874147 0.03771665961718322 0.2272900616772628 2.8223131188358716e-06 5.549394805521815 -0.4739032565769582 VLS(ph)PGVSHR ddPTM_PC-9_Lapatinib_30min_R1 1 VLSPGVSHR 9 0 Q14676;Q14676-3;Q14676-2;Q14676-4;A2AB07;A2AB05 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 VLS(1)PGVSHR 69.26100000000001 0.034727 0.0 8915.8 7580.8 12159.0 7218.5 10106.0 9243.2 7959.5 9474.9 10354.0 6439.3 True False 8788.659057042525 7563.247123362964 11159.333955097309 7749.3725702100965 9511.584949160455 8847.889882951597 8371.603963867397 9915.138443823014 9187.823487546371 7552.3244251720835 1.1637025321303343 1.0014462697278304 1.4776025666883394 1.0260910593805064 1.2594248358105629 1.1715452600872602 1.1084804482133521 1.3128591789271675 1.2165557211662053 1.0 12.88270502453846 -11.811708844189319 2.2632283776063584 0.129372720800796 1.1932521549684085 0.16216358817058873 0.1316608599269721 1728141.5882539472 601815.0153661291 7614242.51019318 0.03219852037763453 1.5427343724740698e-12 11.811708844189319 1.0638794341676125 VLS(ph)PLIIK ddPTM_PC-9_AZD4547_30min_R2 2 VLSPLIIK 8 0 Q8NCN4 Q8NCN4 RNF169 E3 ubiquitin-protein ligase RNF169 1 VLS(1)PLIIK;VLS(1)PLIIK 89.88600000000001 0.009889299999999998 122227000.0 86002.0 78430.0 139166.0 177927.0 173818.0 143600.0 131015.0 147762.0 137741.0 157482.0 True False 113348.84704727257 103780.96371775723 137320.56791055092 136908.67909474697 149686.3710170767 134620.66929928414 142675.08119031452 124928.77813296927 145021.70805617527 151968.60311379036 0.7458701647892344 0.6829105590978459 0.9036114374738883 0.9009010827863774 0.9849822131022367 0.8858452768594806 0.9388457764758351 0.8220696615828315 0.9542873006971484 1.0 17.21341376645549 -5.287702555124415 8.047696229110526 0.9182316634146623 0.7143299898701154 0.7316246899026864 0.050648412222578175 0.10637722128075328 29.49975992998187 0.012643206809952907 0.027224021321008745 5.1558164149754206e-06 5.287702555124415 -0.2039016735445469 VLS(ph)PLIIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VLSPLIIK 8 0 Q8NCN4 Q8NCN4 RNF169 E3 ubiquitin-protein ligase RNF169 1 VLS(1)PLIIK;VLS(1)PLIIK 103.26 0.0040284 109933000.0 111426.0 114886.0 141196.0 161452.0 191713.0 165802.0 171564.0 184895.0 174978.0 119203.0 True False 130288.22103618375 126291.12282487699 144562.64812881174 152406.3678744466 154148.21387328554 157107.0512422605 155312.2159042035 180041.70216244605 177536.72222414648 140813.5602895714 0.9252533688393136 0.8968676210243514 1.026624480139062 1.0823273522879155 1.094697226291932 1.1157096725569815 1.1029634900560488 1.2785821322336088 1.2607927948065294 1.0 17.10342674605773 -5.632774864019007 0.6791719250924696 1.1778416175141044 0.8520965704105394 0.5806906846999005 0.07685074962932564 0.885048512176834 0.630792863427215 0.04124277709228561 0.1909416374684712 2.329298440830865e-06 5.632774864019007 -0.325745047103565 VLS(ph)PLIIK ddPTM_PC-9_Lapatinib_30min_R1 2 VLSPLIIK 8 0 Q8NCN4 Q8NCN4 RNF169 E3 ubiquitin-protein ligase RNF169 1 VLS(1)PLIIK;VLS(1)PLIIK 118.71 0.0034911 121294000.0 133673.0 101735.0 130899.0 106726.0 119471.0 111884.0 106480.0 103418.0 108539.0 95720.0 True False 131766.79850737378 101499.43885807967 120136.98950475229 114574.98606749899 112443.95066902314 107098.9821343427 111993.01338935866 108223.17782597069 96314.19485366001 112265.07446111724 1.173711407041474 0.9041052112180603 1.0701190025608673 1.0205755139563175 1.0015933379883684 0.9539830855537907 0.9975766187920464 0.9639968471535068 0.8579177033995397 1.0 16.776549651163855 VLS(ph)PLRS(ph)PPLIGSESAYESFLSADDK ddPTM_PC-9_AZD4547_30min_R2 3 VLSPLRSPPLIGSESAYESFLSADDK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 VLS(0.985)PLRS(0.96)PPLIGS(0.037)ES(0.009)AY(0.006)ES(0.002)FLS(0.001)ADDK;VLS(1)PLRS(0.998)PPLIGS(0.001)ESAYESFLSADDK;VLS(1)PLRS(0.996)PPLIGS(0.004)ESAYESFLSADDK 81.726 6.8294e-05 51202600.0 47515.8 52027.1 60151.4 77178.3 65758.1 65989.0 65579.0 70291.5 59619.0 55782.7 True False 62624.836009962644 68843.84262960764 59353.75313377347 59386.03532784867 56628.72288242898 61862.69739826236 71415.40395664352 59429.563812980276 62770.33862539923 53829.76465193242 1.1633867696598688 1.2789177711393958 1.1026195919220454 1.1032193009173186 1.0519964790593985 1.1492284574950593 1.3266898790738035 1.104027933193775 1.1660897838078483 1.0 15.71611649734164 -5.272402037223753 24.89298839613773 1.1338134395970176 1.2211522744225471 0.16261442983060437 0.08517670019764165 1197.818327931933 2719895.8080169996 0.02283457798791693 0.04826169664636031 5.340697288303181e-06 5.272402037223753 0.08733883482552951 VLS(ph)PLRS(ph)PPLIGSESAYESFLSADDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VLSPLRSPPLIGSESAYESFLSADDK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 VLS(1)PLRS(0.999)PPLIGS(0.001)ESAYESFLSADDK;VLS(0.995)PLRS(0.981)PPLIGS(0.021)ES(0.002)AYESFLSADDK;VLS(0.999)PLRS(0.989)PPLIGS(0.006)ES(0.005)AY(0.001)ESFLSADDK 84.125 4.7803e-06 39404200.0 40478.4 44286.9 43218.6 50345.6 56482.2 54685.9 60007.0 49566.7 49186.0 43984.7 True False 47330.593635157515 48683.4107500743 44249.095331453245 47524.89925463745 45414.9183708653 51818.07513497503 54322.702546942026 48265.626645259785 49905.25219923005 51958.77792730636 0.9109258439714658 0.9369621975748832 0.8516192469607455 0.914665455009889 0.8740567076924647 0.9972920303759226 1.0454961551047823 0.9289215137582041 0.9604777900868008 1.0 15.665079878484812 -6.766461579313835 24.999994173884016 0.9856862704699136 0.8982186220562888 0.6125730884076419 0.03530275711607195 91.60897267091299 456017.1737291699 0.012715356841219449 0.011558813096101088 1.7121366374224958e-07 6.766461579313835 -0.08746764841362487 VLS(ph)PLRS(ph)PPLIGSESAYESFLSADDK ddPTM_PC-9_Lapatinib_30min_R1 5 VLSPLRSPPLIGSESAYESFLSADDK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 VLS(1)PLRS(1)PPLIGSESAYESFLSADDK;VLS(1)PLRS(0.999)PPLIGS(0.001)ESAYESFLSADDK;VLS(0.996)PLRS(0.955)PPLIGS(0.022)ES(0.02)AY(0.006)ES(0.001)FLSADDK;VLS(0.999)PLRS(0.991)PPLIGS(0.008)ES(0.001)AY(0.001)ESFLSADDK;VLS(0.986)PLRS(0.975)PPLIGS(0.024)ES(0.011)AY(0.003)ES(0.001)FLSADDK 122.41 9.6869e-12 39748700.0 70309.61 98314.41 100134.90000000001 90373.59999999999 114826.5 118491.20000000001 112711.9 120175.0 111346.40000000001 103981.1 True False 69306.98206819677 98086.76902406423 91902.19505389218 97019.97602149188 108072.63102758495 113423.60759247812 118547.57067843764 125758.76922040689 98805.39590242742 121954.09458889319 0.5683038548384156 0.8042925442947559 0.7535802333139707 0.7955450479013917 0.8861746823007247 0.9300516557056053 0.9720671624684769 1.0311975964754545 0.8101851457755482 1.0 16.89597867163546 -3.85529664920625 0.37236014772544224 0.9763580855554936 5.795756767138546e-18 0.7321818167041406 0.06806307367501747 6.306852870068593 0.40706809960277035 0.056934002359450696 3.1578146220173093 0.00013954148833055037 3.85529664920625 -0.9763580855554936 VLS(ph)PLRS(ph)PPLIGSESAYESFLSADDKASGR ddPTM_PC-9_AZD4547_30min_R2 1 VLSPLRSPPLIGSESAYESFLSADDKASGR 30 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 VLS(0.991)PLRS(0.991)PPLIGS(0.017)ES(0.001)AYESFLSADDKASGR 62.831 0.0032125 5031900.0 5418.2 2155.3 5396.4 10026.0 9355.7 5022.2 3520.0 4619.2 3695.1 7243.5 True False 7141.074894438892 2851.9585758113267 5324.840210054879 7714.660600155871 8056.822546137147 4708.16104007567 3833.273180856443 3905.4087786562845 3890.415442303837 6989.907269749812 1.0216265565271927 0.4080109314402115 0.7617898213183978 1.103685686009394 1.152636542262101 0.6735655937026741 0.5484011493894463 0.5587211143068669 0.5565761164157884 1.0 12.771057601155578 -6.9749690260802675 24.9984833624961 0.6265558133283763 0.8721469300668511 0.17712077402452453 0.23179670184878767 387.9483061317916 387443.5605023275 0.08605900478914673 0.07589421057398962 1.059329273937943e-07 6.9749690260802675 0.24559111673847478 VLS(ph)PLRS(ph)PPLIGSESAYESFLSADDKASGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VLSPLRSPPLIGSESAYESFLSADDKASGR 30 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 VLS(0.998)PLRS(0.848)PPLIGS(0.053)ES(0.053)AY(0.03)ES(0.014)FLS(0.005)ADDKASGR;VLS(0.914)PLRS(0.899)PPLIGS(0.078)ES(0.079)AY(0.01)ES(0.018)FLS(0.002)ADDKASGR;VLS(0.99)PLRS(0.989)PPLIGS(0.018)ES(0.002)AYES(0.001)FLSADDKASGR 70.50399999999999 0.00056359 12209800.0 18604.300000000003 6097.2 14684.4 20746.6 24190.300000000003 33353.6 25723.4 28583.2 23531.899999999998 21360.3 True False 21753.64053832566 6702.489721008988 15034.53178689711 19584.235263384704 19450.384366521528 31604.47850034294 23286.69333071155 27832.92128640376 23876.009519519 25232.75330195823 0.862119178117492 0.2656265703865472 0.5958339784398531 0.7761434128500292 0.7708387639573224 1.252518031708027 0.9228756391362313 1.103047335077926 0.9462308466221189 1.0 14.62301001584222 -6.229660044576864 1.634366247738807 1.0384321821227094 0.5495041777002047 0.5700891660953726 0.17111551255446722 0.25010504022190977 1.3250048167513944 0.05892737731462265 0.0814907739413028 5.89304768658015e-07 6.229660044576864 -0.4889280044225047 VLS(ph)PLRSPPLIGSESAYESFLSADDK ddPTM_PC-9_AZD4547_30min_R2 2 VLSPLRSPPLIGSESAYESFLSADDK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 VLS(0.594)PLRS(0.406)PPLIGSESAYESFLSADDK;VLS(0.947)PLRS(0.042)PPLIGS(0.008)ES(0.003)AYESFLSADDK 77.89399999999999 2.6155999999999998e-05 8653100.0 8898.199999999999 10061.400000000001 12935.1 14271.3 16745.6 15637.4 13513.1 16489.6 14905.1 13879.7 True False 11727.642505942216 13313.55078859931 12763.572122355805 10981.272274387047 14420.762490096331 14659.590905993246 14715.739721656591 13941.511213311976 15692.953156635267 13393.77592765189 0.875603905074305 0.9940102671953058 0.9529480104266185 0.8198787506752185 1.0766764031287244 1.0945077015756282 1.0986998588856085 1.0408947625090001 1.1716601234336503 1.0 13.70927511722093 -6.339679375356826 8.980732824181981 1.0844598270025658 0.9197240189486444 0.6594135817873895 0.059601466290195464 0.2461350660607159 26.666558818569502 0.017975799148331473 0.020386265193292324 4.5742576666202775e-07 6.339679375356826 -0.1647358080539214 VLS(ph)PPGRR ddPTM_PC-9_AZD4547_30min_R2 3 VLSPPGRR 8 1 Q86VQ6;H0YBI6;H0YBQ0 Q86VQ6 TXNRD3 Thioredoxin reductase 3 1 VLS(1)PPGRR;VLS(1)PPGRR;VLS(1)PPGRR 78.098 0.010364 65275900.0 102478.0 79485.4 128593.3 193276.0 168184.0 122619.4 100287.0 139778.7 101038.4 141364.7 True False 135063.87232518315 105177.50112828534 126888.0688206303 148719.20428443296 144834.55466715826 114951.9895339601 109212.34871833834 118179.11370998505 106379.08355001811 136415.56488106586 0.9900913612236171 0.771008068030833 0.9301582919167463 1.0901923428905935 1.0617157565079358 0.8426603638241809 0.8005856869306323 0.8663169324777543 0.7798163181948108 1.0 17.05764873826817 -6.802441157671523 24.94447376093662 0.8459398711637177 0.9622698190344867 0.23805769553146272 0.09758573318625631 225.26394908152074 137043.4865672956 0.03654322885944253 0.032228449768350965 1.5760095409737435e-07 6.802441157671523 0.116329947870769 VLS(ph)PPGRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VLSPPGRR 8 1 Q86VQ6;H0YBI6;H0YBQ0 Q86VQ6 TXNRD3 Thioredoxin reductase 3 1 VLS(1)PPGRR;VLS(1)PPGRR;VLS(1)PPGRR 89.029 0.0048281999999999995 41243700.0 58124.0 47455.8 59726.1 69149.1 77020.9 78152.1 70515.0 65440.5 60887.4 55180.9 True False 67963.24519867127 52166.89819954384 61150.19673649562 65274.90011140702 61929.207544156925 74053.66629709097 63835.30871561014 63722.75621494114 61777.76303735614 65184.76035823598 1.0426247611430275 0.8002928585278237 0.938105722878053 1.0013828347711284 0.9500565347454296 1.1360579664650776 0.9792980501084969 0.9775713811746779 0.9477332231927217 1.0 15.99224709361492 -5.67310464780983 4.380889615594381 1.0009146370608715 0.9102390559690393 0.1626626783237639 0.0738057408026321 0.3220109732218908 11.165939167318509 0.020009233123198564 0.03545969551609356 2.1227329056156988e-06 5.67310464780983 -0.09067558109183216 VLS(ph)PPGRR ddPTM_PC-9_Lapatinib_30min_R1 3 VLSPPGRR 8 1 Q86VQ6;H0YBI6;H0YBQ0 Q86VQ6 TXNRD3 Thioredoxin reductase 3 1 VLS(1)PPGRR;VLS(1)PPGRR;VLS(1)PPGRR 106.88 0.0017507000000000002 58747500.0 75930.2 61577.4 63728.1 59811.8 58939.799999999996 63103.7 55477.4 52434.299999999996 66893.0 49060.6 True False 74847.42142410652 61434.82131360417 58488.621615579956 64210.55929831577 55473.07684410526 60404.90185290945 58349.748318997066 54870.58899882311 59358.80592548195 57540.65934085967 1.3007744833218708 1.0676767005688315 1.0164746508917242 1.115916293519421 0.9640674521210045 1.0497777144867695 1.0140611697433726 0.953596806629907 1.0315975973415936 1.0 15.81229413212367 VLS(ph)PPHIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VLSPPHIK 8 0 A0A0D9SG79;Q9NZ09-2;Q9NZ09;Q9NZ09-3;Q9NZ09-4 A0A0D9SG79 UBAP1 Ubiquitin-associated protein 1 1 VLS(1)PPHIK;VLS(1)PPHIK 74.84100000000001 0.015424 29652000.0 152402.0 161991.0 177358.0 182899.0 251217.0 264510.0 332220.0 288830.0 265540.0 223803.0 True False 178200.648523293 178072.39591877707 181586.8873539605 172651.76199655887 201992.83222632337 250638.6299567573 300749.71653548843 281248.51854068134 269423.0201476756 264376.71227642684 0.674040640678556 0.6735555275859102 0.6868490261127728 0.6530520805328638 0.7640341332905443 0.9480359589867913 1.1375802125152035 1.0638172935845185 1.0190875657231582 1.0 18.012235576535915 -6.780245412906582 2.3715735271894327 1.0603853798274068 0.6747025306358587 0.9567154984523264 0.037366241360252746 0.05264853441271762 0.6074316240902977 0.01429647830619924 0.013055664746181138 1.658649366182839e-07 6.780245412906582 -0.38568284919154805 VLS(ph)PPHIK ddPTM_PC-9_Lapatinib_30min_R1 1 VLSPPHIK 8 0 A0A0D9SG79;Q9NZ09-2;Q9NZ09;Q9NZ09-3;Q9NZ09-4 A0A0D9SG79 UBAP1 Ubiquitin-associated protein 1 1 VLS(1)PPHIK 66.056 0.02839 19077000.0 54112.0 59403.0 74421.0 53766.0 96790.0 113600.0 130210.0 125290.0 125440.0 102920.0 True False 53340.35295707455 59265.4560032094 68302.39265336754 57720.13099811818 91097.0024964615 108741.59281453413 136951.636677577 131111.43079363205 111311.62625823994 120709.58486772042 0.4418899544350813 0.49097555979631147 0.5658406722897499 0.47817355234359205 0.7546791134795976 0.9008530095907346 1.1345547814422146 1.0861724935705022 0.9221440565819257 1.0 16.881180711359157 -6.606100858661931 1.7518002364300662 1.0412356980916668 0.492131748854448 0.9324427927793691 0.06565471937737274 0.08287871335399909 0.5209058135215657 0.026334374306988546 0.027014428576855307 2.4768467787105065e-07 6.606100858661931 -0.5491039492372188 down VLS(ph)PPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLSPPK 6 0 B7Z7F3;Q9H6Z4-3;Q9H6Z4-2;Q9H6Z4;K7ESQ0;K7EL01;Q5XUX1;Q5XUX1-2 B7Z7F3 RANBP3;FBXW9 Ran-binding protein 3;F-box/WD repeat-containing protein 9 1 VLS(1)PPK 89.14200000000001 0.03828 36065000.0 61319.0 69229.0 54575.0 68306.0 61680.0 49995.0 65820.0 67252.0 46666.0 47607.0 True False 71699.09559454482 76101.59760147796 55876.274976840046 64479.036271039935 49594.24677358478 47373.17418883249 59585.05310446651 65486.70625938409 47348.40196660168 56237.77224319535 1.2749277351259278 1.3532114549698595 0.9935719845944103 1.1465432164027756 0.8818672005555053 0.8423728803475948 1.0595201539420185 1.164461244591847 0.841932389530788 1.0 15.779251825358344 -5.265514288142696 24.764515907770406 0.9959132724060415 1.3140696107466017 0.5842161965314923 0.10886747252682923 196.95685965526357 1196978.356959206 0.02921340477023879 0.06457966946187595 5.426073994340249e-06 5.265514288142696 0.3181563383405601 VLS(ph)PPKLNEVSSDANR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLSPPKLNEVSSDANR 16 1 B7Z7F3;Q9H6Z4-3;Q9H6Z4-2;Q9H6Z4;K7ESQ0 B7Z7F3 RANBP3 Ran-binding protein 3 1 VLS(1)PPKLNEVSSDANR 89.87700000000001 0.017606999999999998 21093000.0 38730.0 36803.0 36587.0 36150.0 36234.0 30890.0 41445.0 25944.0 28931.0 25606.0 True False 45286.22404763157 40456.558617446375 37459.3728369702 34124.6326998813 29134.207807945364 29270.074021262866 37519.02956418437 25262.997489940215 29354.061142925308 30248.16510301554 1.4971560718939885 1.337488025460861 1.2384014934259846 1.1281554627748083 0.9631727315929282 0.967664449118761 1.2403737362714928 0.8351910737032331 0.9704410513151722 1.0 14.884560008645119 -5.189656489213497 0.7796542409804816 0.9859839013043092 1.6317622163472936 0.7552189702763596 0.0969211525592201 0.8218019931012998 0.5637642079185377 0.04153901237042337 0.41714302393905023 6.461651195430616e-06 5.189656489213497 0.6457783150429843 VLS(ph)PTAAK ddPTM_PC-9_Lapatinib_30min_R1 1 VLSPTAAK 8 0 Q96QC0 Q96QC0 PPP1R10 Serine/threonine-protein phosphatase 1 regulatory subunit 10 1 VLS(0.69)PT(0.31)AAK 68.626 0.043082999999999996 6491800.0 37213.0 75573.0 62590.0 63114.0 80432.0 80781.0 98732.0 115340.0 86292.0 93562.0 True False 36682.33579597158 75398.01536169139 57444.0918043869 67755.61410213195 75701.14789539618 77326.1849397084 103843.85986061381 120699.11746937117 76572.88626495573 109734.06703647143 0.33428393557836295 0.6870976115068437 0.5234845782695238 0.6174528652037709 0.6898600401845673 0.7046689057283196 0.9463228937472996 1.0999238498036836 0.6978041398894458 1.0 16.743651955644758 -6.802592642480591 1.0659889095199573 0.9518670707478492 0.5324487647779423 0.6461919783963728 0.12944302164359942 0.3159812329954754 0.7632099592910414 0.07036698356051815 0.06114788859801127 1.5754599142069354e-07 6.802592642480591 -0.4194183059699068 VLS(ph)PTAAKPSPFEGK ddPTM_PC-9_AZD4547_30min_R2 1 VLSPTAAKPSPFEGK 15 1 Q96QC0 Q96QC0 PPP1R10 Serine/threonine-protein phosphatase 1 regulatory subunit 10 1 VLS(0.884)PT(0.116)AAKPSPFEGK 70.334 0.011290000000000001 180470000.0 125290.0 99359.0 168280.0 202260.0 162220.0 149050.0 131760.0 166610.0 125540.0 142890.0 True False 165129.61380610717 131474.8536788557 166048.49724780125 155632.0818858494 139698.5531210245 139729.87993773227 143486.38474705798 140864.25281692186 132175.78810501035 137887.46459233138 1.1975679899134999 0.9534938804449355 1.204231999904624 1.1286891259185925 1.0131345407941734 1.0133617319808443 1.0406049974976332 1.0215885340512385 0.9585772607814076 1.0 17.07313178123431 -6.267225260930075 23.224514733291358 1.010867809502198 1.114976780584103 0.4045129285903287 0.06701907302479324 195.34062562080587 784095.1266469542 0.020003080750824333 0.023342022717209168 5.404739158907001e-07 6.267225260930075 0.1041089710819052 VLS(ph)RNSADDEELTNDSLTLSQSK ddPTM_PC-9_AZD4547_30min_R2 2 VLSRNSADDEELTNDSLTLSQSK 23 1 A0A0U1RRH6;O94880 A0A0U1RRH6 PHF14 PHD finger protein 14 1 VLS(0.5)RNS(0.5)ADDEELTNDSLTLSQSK;VLS(0.547)RNS(0.453)ADDEELTNDSLTLSQSK 96.016 4.303e-06 14945700.0 69496.0 53467.0 88709.0 116823.0 102737.0 102289.0 76851.0 100589.0 76513.0 85321.0 True False 91594.28239340088 70749.16214582844 87532.66069856905 89891.26224735788 88473.74091970587 95892.85265985041 83690.59011988588 85045.28135526887 80557.3209756147 82333.93775969124 1.1124729957740864 0.8592952562565951 1.0631419203348607 1.091788692406821 1.0745719605678878 1.1646819679599643 1.0164774380663575 1.0329310569778802 0.9784218169029888 1.0 16.329199606615184 -4.430824694890879 23.642697854323295 1.0370379856416168 12.436051963835103 0.08825555466920976 0.0763024175509948 3292.628614768661 831659.5169844182 0.01903623136786522 33613.57411256826 3.708303790866676e-05 4.430824694890879 11.399013978193487 VLS(ph)RNSADDEELTNDSLTLSQSK ddPTM_PC-9_Lapatinib_30min_R1 1 VLSRNSADDEELTNDSLTLSQSK 23 1 A0A0U1RRH6;O94880 A0A0U1RRH6 PHF14 PHD finger protein 14 1 VLS(0.495)RNS(0.495)ADDEELT(0.008)NDSLT(0.001)LSQSK 69.525 0.00053956 6001900.0 26025.0 27065.0 22573.0 27672.0 26632.0 24888.0 22477.0 23693.0 29619.0 20953.0 True False 25653.878727599513 27002.332655368627 20717.135074299826 29707.091191085907 25065.558120526548 23823.59825676164 23640.74907919435 24793.86327554896 26282.996318102774 24574.698131882462 1.0439142971329913 1.0987859346413142 0.8430270420055352 1.2088486715751285 1.0199742021655704 0.9694360487730115 0.9619955025418426 1.0089183249572518 1.069514513547738 1.0 14.584886074597057 -6.518009591955107 24.98596808664609 0.9994398402099868 1.0471477237834759 0.05818695770381177 0.08819996050691659 685.3214606646802 3516728.9366486017 0.02836102269098395 0.02907717692667677 3.0338241775250903e-07 6.518009591955107 0.047707883573489096 VLS(ph)STSEEDEPGVVK ddPTM_PC-9_AZD4547_30min_R2 2 VLSSTSEEDEPGVVK 15 0 Q8NI08-2;Q8NI08;Q8NI08-7;Q8NI08-4;Q8NI08-3 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 1 VLS(0.987)S(0.013)TSEEDEPGVVK;VLS(0.923)S(0.011)T(0.047)S(0.019)EEDEPGVVK 174.83 6.6055e-05 7561400.0 39913.0 38770.0 49444.0 69579.0 57417.0 52090.0 47910.0 66899.0 62779.0 55352.0 True False 52604.5037580266 51301.64431132793 48788.34025386431 53538.63653483394 49445.64063956273 48832.804065457676 52173.89718603184 56561.29673608569 66097.36977413131 53414.14332783756 0.9848422249357877 0.9604505682410024 0.9133974115136198 1.0023307161594315 0.9257031482482545 0.9142298466857137 0.9767805666339434 1.0589198517877931 1.237450713539455 1.0 15.704934177778352 -7.850368584093905 3.2579353289231188 1.1259169894600636 0.9506793001899084 0.556787263807843 0.06046991267331613 0.1584669795887202 3.286177057544043 0.035392753711744204 0.015406650667719518 1.411339237890711e-08 7.850368584093905 -0.17523768927015515 VLS(ph)STSEEDEPGVVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VLSSTSEEDEPGVVK 15 0 Q8NI08-2;Q8NI08;Q8NI08-7;Q8NI08-4;Q8NI08-3 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 1 VLS(0.838)S(0.151)T(0.004)S(0.007)EEDEPGVVK;VLS(0.767)S(0.107)T(0.107)S(0.019)EEDEPGVVK 136.81 3.1388e-06 2249600.0 26819.0 32907.0 23962.0 28129.0 43276.0 35175.0 30182.0 32505.0 27961.0 24441.0 True False 31358.927000605 36173.78948521335 24533.344956391036 26553.023325448437 34796.37845936536 33330.361077951464 27322.94246124293 31651.778191894336 28369.876727985004 28871.959825150465 1.0861378025778536 1.2529038452631205 0.8497291179734863 0.9196820543618935 1.2051962759055281 1.154419765052363 0.9463487282024345 1.096280903117715 0.9826100098432495 1.0 14.817381420412593 -7.619401423899177 0.01031366443808724 4.396042661005225e-07 2.08528286982328 0.03956242996070347 0.12180613929020216 4796.452934443344 42.33687822804761 4243.7062968691935 4309.121251996681 2.402141443740661e-08 7.619401423899177 2.0852824302190136 VLS(ph)STSEEDEPGVVK ddPTM_PC-9_Lapatinib_30min_R1 2 VLSSTSEEDEPGVVK 15 0 Q8NI08-2;Q8NI08;Q8NI08-7;Q8NI08-4;Q8NI08-3 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 1 VLS(0.751)S(0.104)T(0.127)S(0.018)EEDEPGVVK;VLS(0.487)S(0.487)T(0.024)S(0.001)EEDEPGVVK 188.63 2.4980000000000003e-07 5528800.0 26611.0 24263.0 24840.0 29773.0 28730.0 28034.0 27672.0 24970.0 28267.0 30952.0 True False 26231.522260140282 24206.820514214265 22797.751085172884 31962.605739816452 27040.157885353252 26835.051170445822 29104.720759864107 26130.197357466644 25083.272795293924 36302.01195905245 0.722591416964124 0.6668176006751034 0.6280024123976391 0.8804637543469847 0.7448666458446909 0.7392166362766597 0.8017385039896229 0.7198002520339838 0.6909609534476239 1.0 15.14776188818121 -11.365029533062522 2.6760155148238653 1.100471782433552 0.734243538677009 0.5929442391153401 0.0664264265372793 41790118.44951194 29492523.132502653 26949268.191215195 0.017941928624753457 4.314897334971399e-12 11.365029533062522 -0.36622824375654295 VLS(ph)TSPTISK ddPTM_PC-9_Lapatinib_30min_R1 1 VLSTSPTISK 10 0 A0A087WX19;A0A087WX45;Q6IPM2-2;Q6IPM2-3;Q6IPM2-4;Q6IPM2;H7C427 A0A087WX19 IQCE IQ domain-containing protein E 1 VLS(0.459)T(0.314)S(0.217)PT(0.009)ISK 90.913 0.008406700000000001 4989700.0 53221.0 46854.0 59055.0 48070.0 52293.0 59707.0 46022.0 45582.0 47627.0 40253.0 True False 52462.0587804639 46745.51244170118 54199.72585889231 51605.228156819154 49217.22855199366 57153.47079381496 48404.793972624524 47699.906125272144 42262.74572545599 47210.67741624895 1.111232917035152 0.9901470387631491 1.1480395712398286 1.09308383147787 1.0425020619393632 1.2106047598068121 1.025293357810718 1.0103626708151154 0.8951946474487573 1.0 15.526825563572723 -7.74142429577858 2.54298032493506 0.9536289694727569 1.0940948789603506 0.4695747608986163 0.062322544256674044 0.2468352338319583 3.2004739924209344 0.038219483404973414 0.01718480143120227 1.813742811641298e-08 7.74142429577858 0.14046590948759374 VLS(ph)TSSTLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VLSTSSTLTR 10 0 P16144-4;P16144-2;P16144-3;P16144;J3QRK0 P16144-4 ITGB4 Integrin beta-4 1 VLS(0.732)T(0.04)S(0.199)S(0.027)T(0.001)LT(0.001)R;VLS(0.94)T(0.027)S(0.027)S(0.006)TLTR 96.113 0.005656100000000001 11050000.0 31960.0 38624.0 47023.0 34363.0 88993.0 50107.0 41046.0 46233.0 43046.0 35714.0 True False 37370.196761226565 42458.33546287664 48144.20665572056 32437.752516349126 71555.46049159576 47479.30071166782 37157.82573269421 45019.43273791268 43675.466314968806 42188.66548813156 0.8857876002676472 1.0063920005912712 1.1411644833673253 0.768873633262338 1.6960825772440138 1.1254041852787358 0.8807537593988931 1.0670978144728815 1.0352417126646376 1.0 15.364567832498874 -4.605292780681581 1.2358405168877555 1.1011463883591723 0.7147031321609815 0.06834466683047857 0.23041000063313136 6.335199639156852 6.329210277546049 0.07061637996205582 3.4716483894705945 2.481459659213611e-05 4.605292780681581 -0.38644325619819087 VLS(ph)TSSTLTR ddPTM_PC-9_Lapatinib_30min_R1 2 VLSTSSTLTR 10 0 P16144-4;P16144-2;P16144-3;P16144;J3QRK0 P16144-4 ITGB4 Integrin beta-4 1 VLS(0.955)T(0.015)S(0.015)S(0.015)TLTR;VLS(0.917)T(0.039)S(0.039)S(0.004)TLTR 119.34 0.00079819 21375000.0 81159.0 59824.0 36032.0 22403.0 39736.0 28190.0 24364.0 23587.0 44468.0 19031.8 True False 80001.65777726233 59685.48120357557 33069.58804754224 24050.591354217173 37398.80660398177 26984.379414099603 25625.44870603244 24682.938128576927 39459.54557120074 22321.42127172055 3.5840754405105026 2.673910432360877 1.4815180290261694 1.0774668450295926 1.6754670837812224 1.208900593094699 1.1480204774638534 1.1057959897853025 1.7677882197041288 1.0 14.44614127035374 -5.064755667495203 2.0319001030697827 1.2852551922304556 3.696783456605879 0.9073968417601708 0.24191949119242792 0.11341355830117807 0.7586416809086739 0.06553110131905496 0.40964566302880023 8.614782804397478e-06 5.064755667495203 2.4115282643754234 VLS(ph)TSTDLEAAVADALKKPVR ddPTM_PC-9_AZD4547_30min_R2 2 VLSTSTDLEAAVADALKKPVR 21 2 Q7Z460 Q7Z460 CLASP1 CLIP-associating protein 1 1 VLS(0.25)T(0.25)S(0.25)T(0.25)DLEAAVADALKKPVR;VLS(0.417)T(0.417)S(0.073)T(0.093)DLEAAVADALKKPVR 149.71 1.056e-06 29389500.0 49949.0 54067.0 101230.0 129233.0 101077.0 79007.0 87006.0 93927.0 79046.0 96445.0 True False 65831.74299625863 71543.1004121889 99887.62405749311 99440.32847994649 87044.2032660203 74066.67980033804 94749.365447044 79412.7403777383 83224.21018439262 93068.48990557349 0.7073472779353245 0.7687145293189557 1.0732700633569778 1.0684639729390455 0.9352703944625579 0.7958298224832645 1.0180606297918438 0.8532720414644076 0.894225427626807 1.0 16.50600517835739 -5.097877019347113 6.057863916916614 0.9490875667273233 0.7217069805075118 0.5106678327353715 0.08558631821595758 0.17969359024266948 8.991273161898627 0.023324582524362338 0.06460100366775814 7.982206901486618e-06 5.097877019347113 -0.2273805862198115 VLS(ph)TSTDLEAAVADALKKPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VLSTSTDLEAAVADALKKPVR 21 2 Q7Z460 Q7Z460 CLASP1 CLIP-associating protein 1 1 VLS(0.286)T(0.286)S(0.214)T(0.214)DLEAAVADALKKPVR;VLS(0.415)T(0.415)S(0.075)T(0.095)DLEAAVADALKKPVR;VLS(0.271)T(0.271)S(0.229)T(0.229)DLEAAVADALKKPVR 123.17 3.8046999999999997e-07 49230300.0 136783.0 93154.0 122439.0 188566.0 197751.0 193356.0 176624.0 183267.0 176085.0 135160.0 True False 159937.66031260483 102401.71348666161 125358.41011249318 178001.25835922058 159003.11111743125 183216.07097621585 159892.89607297603 178456.43543743715 178659.91000490868 159663.43807402847 1.0017175017767639 0.6413598173877649 0.7851416180476481 1.1148529713902924 0.9958642569359489 1.1475142536468939 1.001437135525299 1.1177038249338915 1.1189782216895043 1.0 17.28467445688996 -5.757153694382712 24.99998195178808 1.0729821555397259 0.7926015851565386 0.6017088887481007 0.09719842367181025 64.6903223833515 377356.0484124052 0.025236187506628913 0.04181808454807302 1.7492275372538634e-06 5.757153694382712 -0.2803805703831873 VLS(ph)TSTDLEAAVADALKKPVR ddPTM_PC-9_Lapatinib_30min_R1 2 VLSTSTDLEAAVADALKKPVR 21 2 Q7Z460 Q7Z460 CLASP1 CLIP-associating protein 1 1 VLS(0.423)T(0.423)S(0.077)T(0.077)DLEAAVADALKKPVR;VLS(0.775)T(0.158)S(0.034)T(0.034)DLEAAVADALKKPVR 100.47 6.351100000000001e-05 29185400.0 254915.0 169884.0 174889.0 145910.0 135742.6 156306.5 111658.9 93032.0 175682.0 103495.7 True False 251279.86535431384 169490.64403564145 160510.3015110628 156640.70814149114 127758.48714821978 149621.6353632479 117440.05149080642 97354.60635001329 155894.84314652512 121384.79384564825 2.0701099156937146 1.3963087028113599 1.3223262686030193 1.2904475361277457 1.0525081692742853 1.2326225602319294 0.9675021703306764 0.8020329669448422 1.284302903251288 1.0 16.889228177599442 -1.5228787452818682 0.5750765078317538 1.0377939475596574 53.22728036576236 0.8160645757486491 0.14118098527052172 60.679252163339555 0.512112872799459 0.06600987580685905 3947.6339545572732 0.029999999999894267 1.5228787452818682 52.189486418202705 up VLSEDAIR ddPTM_PC-9_Lapatinib_30min_R1 1 VLSEDAIR 8 0 P23919-2;P23919;H7C312 P23919-2 DTYMK Thymidylate kinase 0 93.195 0.034125 2543800.0 22761.0 22386.0 19726.0 20901.0 20400.0 17881.0 17196.0 19857.0 19096.0 20278.0 False True 22436.423966143804 22334.166592391743 18104.204424562016 22438.129263692063 19200.11210794314 17116.27131264686 18086.324739325806 20779.628711542457 16945.207390205294 23783.025281263413 0.9433797299042321 0.9390801350233142 0.7612237808461126 0.9434514322014838 0.8073031870789477 0.7196843593372155 0.7604719973776615 0.8737167986745962 0.7124916695755672 1.0 14.537644621995128 -5.243343486556565 23.33263496631736 0.815702055661474 0.9412300261739894 0.2186900962011169 0.08923068793635144 481.8898476544535 621336.1115370366 0.02186235193420385 0.05751395511206618 5.7102682889612904e-06 5.243343486556565 0.1255279705125154 VLSEPIGPES(ph)PSSTECPR ddPTM_PC-9_AZD4547_30min_R2 2 VLSEPIGPESPSSTECPR 18 0 Q56NI9;Q56NI9-2 Q56NI9 ESCO2 N-acetyltransferase ESCO2 1 VLSEPIGPES(0.768)PS(0.098)S(0.098)T(0.036)ECPR;VLSEPIGPES(0.909)PS(0.012)S(0.04)T(0.04)ECPR 119.96 0.0005601 0.0 4083.87 4774.3 9390.3 13370.099999999999 10058.400000000001 9531.2 6008.5 8995.3 6087.8 7945.7 True False 5382.455710227042 6317.499108474929 9265.778486486972 10287.830010985841 8661.964780622078 8935.21255727953 6543.244859993161 7605.283076430314 6409.588679509979 7667.523461482858 0.7019809899852728 0.8239295439016705 1.2084447518201686 1.3417409236066726 1.1296952430774696 1.165332274777482 0.8533713516316692 0.9918825960735298 0.8359398848543462 1.0 12.904544960593663 -7.2673645327750584 24.588602127583087 0.919622008647085 1.0735082567558345 0.126939645666157 0.18031676915988515 906.0879519173815 3760124.07645315 0.08270023114365564 0.05746188165381697 5.40300621652761e-08 7.2673645327750584 0.1538862481087495 VLSEPIGPES(ph)PSSTECPR ddPTM_PC-9_Lapatinib_30min_R1 1 VLSEPIGPESPSSTECPR 18 0 Q56NI9;Q56NI9-2 Q56NI9 ESCO2 N-acetyltransferase ESCO2 1 VLSEPIGPES(0.925)PS(0.024)S(0.043)T(0.008)ECPR 148.44 3.8476e-12 0.0 3405.7 3862.1 5554.8 2447.1 4827.5 5960.6 3933.1 3203.9 3783.3 5106.6 True False 3357.1340934711093 3853.1575447367163 5098.1057861480795 2627.067897286296 4543.555941230171 5705.679032837245 4136.736673193902 3352.7648904119915 3357.1849140848167 5989.269005883217 0.5605248470511878 0.6433435434193701 0.8512066800038947 0.4386291373297385 0.7586161077031384 0.9526503196354341 0.6906914131140903 0.5597953418219476 0.5605333323293841 1.0 12.548164216567303 VLSPES(ph)LSCTEIPIPLNER ddPTM_PC-9_AZD4547_30min_R2 1 VLSPESLSCTEIPIPLNER 19 0 Q9P266 Q9P266 KIAA1462 Junctional protein associated with coronary artery disease 1 VLS(0.161)PES(0.83)LS(0.007)CT(0.002)EIPIPLNER 90.37899999999999 0.0010007 1281800.0 5799.6 4820.5 8853.2 11694.0 9083.9 7922.4 6943.6 8475.4 5961.3 8023.1 True False 7643.75216082607 6378.632354984688 8735.800783421879 8998.128970498987 7822.757284527639 7427.011075603422 7561.5669484644295 7165.721675316825 6276.4021477648475 7742.213711041583 0.9872825068009823 0.8238770709581138 1.1283337181668451 1.1622165579937784 1.0104031710428232 0.9592877893581477 0.976667298356861 0.9255391213364994 0.8106728103893253 1.0 12.918530416059362 -7.412033783861876 1.5263527370335668 0.9020470580569084 1.020592634239076 0.18189847113197033 0.0961530774065274 0.7286401261217976 3.2825322467158418 0.06610732928898161 0.034715897769840874 3.87227521237164e-08 7.412033783861876 0.11854557618216766 VLSPLRS(ph)PPLIGS(ph)ESAYESFLSADDKASGR ddPTM_PC-9_AZD4547_30min_R2 1 VLSPLRSPPLIGSESAYESFLSADDKASGR 30 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 VLS(0.155)PLRS(0.846)PPLIGS(0.713)ES(0.216)AY(0.051)ES(0.016)FLS(0.003)ADDKASGR 71.265 0.00044619999999999995 7682000.0 15202.0 8313.6 22191.0 38904.0 27087.0 20142.0 14486.0 18853.0 13449.0 23150.0 True False 20035.919778756786 11000.808618691151 21896.73284065818 29935.283860808322 23326.437605653973 18882.51755589268 15775.22593689955 15939.702048841145 14159.886683322335 22339.525546311597 0.8968820639104776 0.4924369855521599 0.980178956588157 1.340014307768091 1.044177843316163 0.8452515035177328 0.7061576085936231 0.7135201692532317 0.6338490338108468 1.0 14.447310925296726 -7.009106911975747 5.199856526606542 0.7427671836509397 0.948942683122858 0.14413914280885565 0.21319147962189028 0.3694477898161853 30.66140250278892 0.08832000123870776 0.07256934384568589 9.792488901946995e-08 7.009106911975747 0.20617549947191827 VLSPLRS(ph)PPLIGSESAYESFLSADDK ddPTM_PC-9_AZD4547_30min_R2 1 VLSPLRSPPLIGSESAYESFLSADDK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 VLS(0.197)PLRS(0.403)PPLIGS(0.377)ES(0.019)AY(0.003)ES(0.001)FLS(0.001)ADDK 56.588 0.0020106 1444600.0 2572.5 900.59 2499.8 3035.1 2813.3 3417.8 2741.7 3097.1 2394.0 1239.5 True False 3390.501488675954 1191.6881055026784 2466.6510186596965 2335.404586827557 2422.721856092826 3204.084425704001 2985.7059886233264 2618.5143592778795 2520.5419525521356 1196.1054822744381 2.8346174638617927 0.9963068668798675 2.0622353590163884 1.9525072173289435 2.0255085291356845 2.6787640999783044 2.496189535847539 2.1892001985466023 2.1072906945959593 1.0 10.224128908348488 -6.531319285040802 24.836631679124924 2.211333073992545 1.910847335901499 0.0 0.5909878901530043 588.9837380127891 1733093.1868779175 0.18494993148763794 0.18523304255615372 2.942257746551964e-07 6.531319285040802 -0.3004857380910462 VLSPLRS(ph)PPLIGSESAYESFLSADDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VLSPLRSPPLIGSESAYESFLSADDK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 VLS(0.005)PLRS(0.984)PPLIGS(0.007)ES(0.002)AY(0.001)ESFLSADDK;VLS(0.198)PLRS(0.787)PPLIGS(0.011)ES(0.002)AY(0.002)ES(0.001)FLSADDK 83.82600000000001 1.162e-06 27463000.0 45388.0 44750.6 58616.8 56222.5 66940.3 46509.8 50929.6 51044.3 52510.6 45692.7 True False 53071.29194613745 49193.14382158778 60014.44681745195 53072.53560080433 53823.82874996434 44070.74421217649 46105.17958962682 49704.4412109064 53278.46818470476 53976.42480678581 0.9832309593699772 0.9113820338727456 1.111864059768313 0.9832540000710116 0.9971729128528296 0.8164813503290052 0.8541725346698132 0.9208546395732689 0.9870692320845729 1.0 15.720041800882987 -6.59988643868008 24.689051249245246 0.90691090464032 0.9983042486518127 0.25669258881007884 0.06866529035668359 42.08508470667455 13490.569972445332 0.023171182556692448 0.02317118269626793 2.512543337015961e-07 6.59988643868008 0.09139334401149268 VLSPLRS(ph)PPLIGSESAYESFLSADDK ddPTM_PC-9_Lapatinib_30min_R1 1 VLSPLRSPPLIGSESAYESFLSADDK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 VLS(0.06)PLRS(0.938)PPLIGS(0.001)ESAYESFLSADDK 87.16 4.828899999999999e-07 3900300.0 4375.7 6733.0 6866.9 5804.7 8915.2 6689.9 5312.4 7659.1 6328.1 7619.7 True False 4313.3017155948955 6717.410152174289 6302.329989000551 6231.597001911548 8390.825463957577 6403.7885719185815 5587.450078227166 8014.9697469192215 5615.362740152811 8936.754992387956 0.4826474172413621 0.751660995282512 0.7052145878866183 0.6972997477517762 0.9389118836876043 0.716567543518103 0.6252213564080451 0.8968545913752943 0.6283447118037586 1.0 13.1255353569832 -14.522878745280336 0.051573765494469105 1.8997792866517615 0.27414055425346 0.3400553389306933 0.12244344014533547 674.611635337834 2.5586679615785313 85.58904281281382 18.19325711536761 3.0000000000000132e-15 14.522878745280336 -1.6256387323983015 VLSPLRS(ph)PPLIGSESAYESFLSADDKASGR ddPTM_PC-9_AZD4547_30min_R2 2 VLSPLRSPPLIGSESAYESFLSADDKASGR 30 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 VLS(0.043)PLRS(0.923)PPLIGS(0.012)ES(0.014)AY(0.006)ES(0.001)FLSADDKASGR;VLS(0.106)PLRS(0.889)PPLIGS(0.003)ES(0.001)AYESFLSADDKASGR 72.05199999999999 1.251e-05 93401000.0 34166.0 13287.2 42908.0 76127.0 60501.0 35992.0 25075.9 31856.0 23970.0 41193.0 True False 45030.077303052516 17582.027554642154 42339.01188441085 58577.096300425546 52101.480473277625 33741.41455027746 27307.606521544913 26933.387178055644 25237.005264275114 39750.845608173375 1.1328080350017422 0.44230574936566946 1.0651097161994791 1.4736062945131716 1.3107011857520026 0.8488225604775491 0.6869691978560087 0.6775550750175169 0.6348797082969728 1.0 15.27869793030474 -6.987860599555852 22.154526504801225 0.7293969626211314 1.0707072132053164 0.264478139362209 0.26558392879874826 86.66300774936451 158157.5416216165 0.10299272289994267 0.0907196682530349 1.0283463251847294e-07 6.987860599555852 0.34131025058418496 VLSPLRS(ph)PPLIGSESAYESFLSADDKASGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLSPLRSPPLIGSESAYESFLSADDKASGR 30 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 VLS(0.035)PLRS(0.943)PPLIGS(0.015)ES(0.007)AY(0.001)ESFLSADDKASGR 69.71 2.6415e-05 19452000.0 23308.0 6409.8 17938.0 33526.0 34829.0 46667.0 33619.0 45332.0 37623.0 29225.0 True False 27253.584046015938 7046.122583107562 18365.70995024384 31647.646912758508 28004.50747206848 44219.70036744168 30434.36493951776 44142.08303322428 38173.16519927689 34523.261155027285 0.7894266976585225 0.20409782701196244 0.531980738081849 0.9167050230464676 0.8111779285946877 1.2808668384157675 0.8815611249137714 1.2786185764723532 1.1057230378051381 1.0 15.075281131145179 -6.006448865211033 1.4761633717898595 1.099169680637588 0.46206429152093287 0.6220345469106849 0.1921835301743027 0.24154679670118348 1.0648152237321717 0.06446963700843174 0.11259932912875532 9.85260642733273e-07 6.006448865211033 -0.637105389116655 VLSPLRS(ph)PPLIGSESAYESFLSADDKASGR ddPTM_PC-9_Lapatinib_30min_R1 2 VLSPLRSPPLIGSESAYESFLSADDKASGR 30 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 VLS(0.106)PLRS(0.808)PPLIGS(0.063)ES(0.021)AY(0.003)ESFLSADDKASGR;VLS(0.252)PLRS(0.71)PPLIGS(0.017)ES(0.017)AY(0.003)ESFLSADDKASGR 65.15100000000001 5.3493000000000004e-05 20882290.0 63583.0 14111.04 27688.78 22901.12 18416.9 19810.2 11717.06 10404.0 27348.0 14033.0 True False 62676.29476030587 14078.366753859713 25412.3153901817 24585.344760696793 17333.654151018534 18962.96392583171 12323.712034785112 10887.40782166932 24267.78025279295 16458.585352202874 3.8081216227928762 0.8553813376175381 1.5440157733107012 1.493770225969403 1.0531679230073403 1.1521624441005582 0.7487710377936986 0.6615032573387063 1.4744754627131345 1.0 14.006552718160208 -4.758113702506185 24.999024058170317 1.1125978031205543 3.8081253619037825 0.8813911614261789 0.2970122248971569 31.18673153450484 234392.0465464531 0.07792254343018327 0.5474973751996537 1.7453651395816397e-05 4.758113702506185 2.695527558783228 VLSPLRSPPLIGSESAYESFLSADDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VLSPLRSPPLIGSESAYESFLSADDK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 0 ; 78.513 0.00094196 2231900.0 3688.58 5050.9 3190.9399999999996 5536.7699999999995 6112.1 4206.2 5475.599999999999 3907.7 3051.64 3131.39 False True 4312.983741224191 5552.319971764795 3267.024111307339 5226.562727350536 4914.47788107697 3985.619467408089 4956.911528088981 3805.1270155503917 3096.264461864318 3699.086218930397 1.1659592358653659 1.5009977175850382 0.8831976109635016 1.4129334700562384 1.328565378099786 1.0774605487731896 1.340036764409965 1.0286667545290837 0.8370349536647494 1.0 11.852953212097145 -7.9330510920110555 4.915776583969808 0.9212870060101274 1.242572632344251 0.3873052343409076 0.16999189059857817 0.19333667015054193 8.919728263782975 0.09453502563841205 0.04296224068098064 1.166672357330913e-08 7.9330510920110555 0.3212856263341236 VLSPLRSPPLIGSESAYESFLSADDKASGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLSPLRSPPLIGSESAYESFLSADDKASGR 30 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 0 102.92 1.5206e-12 2589800.0 2648.1 844.59 2819.9 4549.1 6197.3 6384.9 4148.0 8346.2 5650.3 4002.8 False True 3096.3710276409292 928.4353134991444 2887.137110530302 4294.228675381189 4982.983552690286 6050.064604025941 3755.0714110806316 8127.121093529874 5732.924948182604 4728.475953852637 0.654834889266612 0.19634980119602383 0.610585131172749 0.9081633738419173 1.0538244460417068 1.2794956901697911 0.7941398978715539 1.7187612188041501 1.2124255265613793 1.0 12.207159544734084 -5.930299048181851 1.3864476859597012 1.2217034057256266 0.40243896540911467 0.613306985503957 0.24698767449339443 0.2699832170570058 1.053520663848271 0.08562636701799012 0.16706023908325285 1.174088817889552e-06 5.930299048181851 -0.8192644403165119 VLSPLRSPPLIGSESAYESFLSADDKASGR ddPTM_PC-9_Lapatinib_30min_R1 1 VLSPLRSPPLIGSESAYESFLSADDKASGR 30 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 0 77.675 7.071599999999999e-06 2040800.0 6535.3 813.55 3872.5 737.32 1763.7 2055.7 815.69 351.89 1983.7 1976.1 False True 6442.105423572759 811.6662749593627 3554.117998282285 791.5449724274163 1659.9626335676135 1967.7825030707527 857.9224369981779 368.2400940376029 1760.2748167129373 2317.666252012262 2.7795656160500006 0.3502084367214872 1.5334899902850558 0.3415267283372552 0.716221600986073 0.8490361808402179 0.37016651394621897 0.15888400399232921 0.7595031489907652 1.0 11.178457115357928 -4.756272645377488 24.999835739543155 0.6627010344961148 2.77956889871124 0.7318769505403825 0.38199653885788204 82.77296585574896 400462.1823781543 0.09380139762010832 0.7720147266115603 1.7527797801831234e-05 4.756272645377488 2.1168678642151253 VLSPT(ph)AAKPSPFEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLSPTAAKPSPFEGK 15 1 Q96QC0 Q96QC0 PPP1R10 Serine/threonine-protein phosphatase 1 regulatory subunit 10 1 VLS(0.084)PT(0.882)AAKPS(0.033)PFEGK 65.298 0.024646 143750000.0 80791.0 71038.0 81010.0 113620.0 117050.0 97332.0 120840.0 100390.0 126240.0 91173.0 True False 94467.32060501419 78090.18316621339 82941.58563213564 107254.23976100999 94114.89275045568 92227.73857680669 109393.16039416163 97754.86887199724 128086.02117738404 107701.94317492894 0.877118070670098 0.7250582567426822 0.7701029636709743 0.9958431259388534 0.8738458190823425 0.8563238123476646 1.0157027549306685 0.907642573479146 1.1892637904345644 1.0 16.716684753878297 -6.991217058430807 0.5653664713431139 1.063486731345989 0.7930065427288838 0.4883159812054154 0.09117189235041631 0.7567865658782035 0.5148043181732848 0.08023498545894925 0.07777141703907918 1.0204293502325467e-07 6.991217058430807 -0.2704801886171052 VLSQSTPGT(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 2 VLSQSTPGTPSK 12 0 Q6MZP7-3;Q6MZP7 Q6MZP7-3 LIN54 Protein lin-54 homolog 1 VLSQST(0.002)PGT(0.995)PS(0.003)K;VLSQS(0.001)TPGT(0.994)PS(0.004)K 174.24 0.0027488000000000005 36558000.0 77018.0 66861.0 100646.0 112870.0 114449.0 107273.0 98269.0 107545.0 92045.0 106253.0 True False 101508.12192608128 88472.51071188273 99311.36827907176 86849.56532411657 98559.73188354174 100565.20235196459 107014.75062772227 90926.39138824701 96910.3107864081 102533.1148108963 0.9900032990638641 0.8628676781647978 0.9685784779115854 0.8470391783600334 0.9612478082355858 0.9808070547494713 1.0437091550870325 0.8868002455201348 0.9451610922494802 1.0 16.64573040229265 -6.491878063620842 24.92198094280373 0.9689998426971002 0.9153249337435633 0.18248312802838584 0.05462093685627295 1126.0756627310975 905272.652117972 0.016637889968933377 0.018844381536951973 3.221973294161366e-07 6.491878063620842 -0.05367490895353688 VLSQSTPGT(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VLSQSTPGTPSK 12 0 Q6MZP7-3;Q6MZP7 Q6MZP7-3 LIN54 Protein lin-54 homolog 1 VLSQSTPGT(0.884)PS(0.116)K;VLSQS(0.002)T(0.001)PGT(0.499)PS(0.499)K;VLSQST(0.001)PGT(0.896)PS(0.104)K;VLSQST(0.003)PGT(0.929)PS(0.067)K 153.2 0.00015074 41770000.0 193214.0 191893.0 199416.0 204038.0 272001.0 195984.0 220024.0 225662.0 194931.0 166287.0 True False 225921.31404955022 210942.86886334323 204170.83372939102 192606.41236012097 218704.35662551594 185706.25402988592 199181.73388418645 219738.61160865292 197781.49710177942 196433.5167728327 1.1501159158638847 1.073863932840392 1.039388985564547 0.9805170498620274 1.1133759666810759 0.9453898554626378 1.013990571245191 1.118641132219669 1.0068622725443825 1.0 17.583681587167007 -4.814298576509986 1.9563986940809883 1.0293537557679038 1.1811703952945691 0.354733051176623 0.05113803321479334 0.8184948644681915 3.5980542097466004 0.01364415475791777 0.2225756137436578 1.5335622995552883e-05 4.814298576509986 0.15181663952666535 VLSQSTPGT(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 2 VLSQSTPGTPSK 12 0 Q6MZP7-3;Q6MZP7 Q6MZP7-3 LIN54 Protein lin-54 homolog 1 VLSQSTPGT(0.95)PS(0.05)K;VLSQSTPGT(1)PSK 228.03 3.5616999999999995e-15 35560000.0 252055.0 236894.0 225337.0 219264.0 229722.0 195711.0 178902.0 191252.0 205022.0 176433.0 True False 248460.6494787742 236345.486497724 206810.66168597477 235389.40600326232 216210.2036108293 187340.8967546238 188164.67018579127 200138.26611975237 181930.26338262839 206929.2089678047 1.2007036160730271 1.142156236312178 0.9994271118977294 1.1375359098767233 1.0448510613330988 0.9053380993872713 0.9093190426058559 0.9671822896249078 0.8791908319281025 1.0 17.65877777675781 -6.591467384338024 3.647959331412381 0.9290121341133292 1.1118356558277958 0.7075655755781427 0.05692908977323022 0.13365420453192797 3.5832992109077884 0.01980011161846854 0.020097039433519145 2.561725643323262e-07 6.591467384338024 0.18282352171446659 VLSRNS(ph)ADDEELTNDSLTLSQSK ddPTM_PC-9_Lapatinib_30min_R1 1 VLSRNSADDEELTNDSLTLSQSK 23 1 A0A0U1RRH6;O94880 A0A0U1RRH6 PHF14 PHD finger protein 14 1 VLS(0.43)RNS(0.57)ADDEELTNDSLTLSQSK 75.225 0.00018733 5571700.0 33918.0 29547.0 33726.0 28421.0 32435.0 30572.0 27205.0 26962.0 36663.0 27715.0 True False 33434.32310020058 29478.58573686228 30953.17846612484 30511.17514967667 30527.237069663504 29264.50682681281 28613.54178491267 28214.75294962019 32533.626861494395 32505.500822083828 1.0285743106436225 0.906879912363476 0.9522443181400128 0.9386465176056528 0.9391406468939462 0.900293983685705 0.8802676796621756 0.8679993304533687 1.0008652701450291 1.0 14.98839626191233 -4.754803299513853 24.962276180748688 0.9261751687765739 1.0285744870661353 0.3047942282799021 0.04308831284320169 263.77871051690175 992137.403625183 0.010514665800262918 0.09948410339299783 1.758719992365476e-05 4.754803299513853 0.10239931828956139 VLSSAAS(ph)LPGSELPSSRPEGSQGGELSR ddPTM_PC-9_AZD4547_30min_R2 2 VLSSAASLPGSELPSSRPEGSQGGELSR 28 1 O15027;O15027-5;A0A0C4DH09;Q8N9G1 O15027 SEC16A Protein transport protein Sec16A 1 VLS(0.015)S(0.037)AAS(0.795)LPGS(0.05)ELPS(0.008)S(0.008)RPEGS(0.072)QGGELS(0.014)R;VLS(0.015)S(0.041)AAS(0.895)LPGS(0.03)ELPS(0.008)S(0.008)RPEGS(0.003)QGGELS(0.001)R 47.806000000000004 0.011294 39387000.0 13379.300000000001 3724.1 29997.0 34064.0 24919.0 22826.0 15514.699999999999 22930.1 15625.1 16478.8 True False 17633.639093271984 4927.842496255259 29599.220180308377 26211.07108355374 21459.42698324996 21398.68661159797 16895.47824404358 19386.779926278698 16451.01088672613 15901.882227756358 1.1089026343367634 0.3098905164606129 1.8613658280428993 1.64829991243445 1.3494897444148493 1.3456700474266543 1.0624829188178067 1.2191500130996777 1.0345323057424787 1.0 13.956909919897729 -8.010487543177707 1.2559702830538486 1.0099176770358966 1.2639009986640568 0.052457838928121836 0.38555611695274655 1.7528216518376465 5.00081023354151 0.37708368153273986 0.12929074107563107 9.7614078057055e-09 8.010487543177707 0.2539833216281602 VLSSAAS(ph)LPGSELPSSRPEGSQGGELSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLSSAASLPGSELPSSRPEGSQGGELSR 28 1 O15027;O15027-5;A0A0C4DH09;Q8N9G1 O15027 SEC16A Protein transport protein Sec16A 1 VLS(0.008)S(0.019)AAS(0.493)LPGS(0.466)ELPS(0.003)S(0.003)RPEGS(0.008)QGGELS(0.001)R 52.059 0.0048794 12371000.0 12695.0 11148.0 7856.9 12019.0 12475.0 14952.0 10126.0 9751.1 9123.1 10835.0 True False 14844.012762320754 12254.699765434669 8044.238293459179 11345.614396123747 10030.613302536807 14167.890798508331 9166.791974108595 9495.143957144464 9256.508078290484 12799.29973018719 1.1597519454373821 0.9574507999474315 0.6284905004987748 0.8864246197286152 0.7836845385282738 1.1069270270383087 0.7161948049773916 0.7418487071406052 0.7232042590938769 1.0 13.643777259819833 VLSSAAS(ph)LPGSELPSSRPEGSQGGELSR ddPTM_PC-9_Lapatinib_30min_R1 1 VLSSAASLPGSELPSSRPEGSQGGELSR 28 1 O15027;O15027-5;A0A0C4DH09;Q8N9G1 O15027 SEC16A Protein transport protein Sec16A 1 VLS(0.036)S(0.091)AAS(0.753)LPGS(0.097)ELPS(0.005)S(0.005)RPEGS(0.01)QGGELS(0.004)R 46.67100000000001 0.013006 15655000.0 12655.0 11738.0 11724.0 4539.7 11733.0 10134.0 11412.0 14912.0 18359.0 11879.0 True False 12474.537379357225 11710.821382180573 10760.09797594874 4873.564681995256 11042.888007965536 9700.592443507814 12002.857520655152 15604.865958932423 16291.21609115934 13932.26932222746 0.8953701002216073 0.840553761295527 0.7723148129775343 0.3498040821117347 0.7926122982957111 0.6962679387794741 0.8615148934499756 1.1200519885182318 1.1693153293533043 1.0 13.766142646338261 -7.604489467005708 2.974509687449298 1.1117555623637267 0.7191755395369862 0.5687755508105188 0.14429387770044583 0.19665689066340494 3.499005984312017 0.08323171686380018 0.04378691304994499 2.4860538580487767e-08 7.604489467005708 -0.39258002282674054 VLSSAASLPGSELPSSRPEGSQGGELS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 VLSSAASLPGSELPSSRPEGSQGGELSR 28 1 O15027;O15027-5;A0A0C4DH09;Q8N9G1 O15027 SEC16A Protein transport protein Sec16A 1 VLSSAASLPGSELPS(0.008)S(0.008)RPEGS(0.083)QGGELS(0.902)R;VLSSAAS(0.001)LPGS(0.002)ELPS(0.142)S(0.142)RPEGS(0.159)QGGELS(0.554)R 52.227 0.0046257 31177000.0 3009.8999999999996 3117.0 4758.6 8419.4 8338.5 6880.8 8344.3 8154.4 3924.7 5741.1 True False 3966.9855901907677 4124.509293742821 4695.497854785993 6478.437408433311 7180.84320798707 6450.542488262646 9086.926534948981 6894.324849470646 4132.151629566147 5540.10583645484 0.7160487014683595 0.7444820397839419 0.8475465980972452 1.1693706942932551 1.2961563226348312 1.1643356063375139 1.6402081121186274 1.2444391953859102 0.745861496431329 1.0 12.43569782199613 -5.705556357766172 2.9082589946052755 1.2188958811373605 0.738176167736214 0.4356029022678395 0.2144000322139494 0.23226331012428314 3.976266599759168 0.0636652973417708 0.11733563010815863 1.969897559875176e-06 5.705556357766172 -0.4807197134011465 VLSSAASLPGSELPSSRPEGSQGGELS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLSSAASLPGSELPSSRPEGSQGGELSR 28 1 O15027;O15027-5;A0A0C4DH09;Q8N9G1 O15027 SEC16A Protein transport protein Sec16A 1 VLSSAAS(0.001)LPGS(0.003)ELPS(0.008)S(0.008)RPEGS(0.042)QGGELS(0.939)R 44.45399999999999 0.016349000000000002 11386000.0 2797.5 5548.6 5219.4 5112.9 2623.9 4722.0 6337.5 4565.6 4599.2 4648.5 True False 3271.0614968564264 6099.428338580089 5343.850290684727 4826.440789245453 2109.7656308237524 4474.370007394084 5737.166120473359 4445.757837653062 4666.454599168436 5491.236252494247 0.5956876277852067 1.1107568602260716 0.9731597849678069 0.8789351918801839 0.3842059481351668 0.8148201610086837 1.044785883664613 0.8096096458486366 0.8498003700075414 1.0 12.42291526714617 -9.296407111907904 13.170568843058662 0.9999688323079002 0.8353399381259268 0.06049095487771061 0.20071478830586745 259203701.64828882 0.0 0.2015355724029721 0.05038389310074305 5.053507191766843e-10 9.296407111907904 -0.16462889418197346 VLSSAASLPGSELPSSRPEGSQGGELS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 VLSSAASLPGSELPSSRPEGSQGGELSR 28 1 O15027;O15027-5;A0A0C4DH09;Q8N9G1 O15027 SEC16A Protein transport protein Sec16A 1 VLSSAAS(0.001)LPGS(0.01)ELPS(0.026)S(0.071)RPEGS(0.089)QGGELS(0.803)R 40.92 0.035003 17010000.0 1623.6 3665.1 1422.6 3930.6 1878.4 3308.7 1867.2 3713.7 1766.9 1734.7 True False 1600.447166268225 3656.6136861330733 1305.6393193948038 4219.669436097222 1767.9162050764903 3167.1946139564143 1963.8744797202323 3886.2520595283904 1567.8931157181473 2034.5405836575437 0.7866381133528738 1.7972675086969703 0.641736679957312 2.074015858907773 0.8689510640767184 1.5567124290352914 0.9652668005224683 1.9101373994427673 0.7706374246413444 1.0 10.990487343278438 VLSSIEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLSSIEQK 8 0 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 113.26 0.017125 8132800.0 97059.0 104380.0 86150.0 97830.0 106320.0 76200.0 101330.0 89067.0 74460.0 72720.0 False True 113489.17169736847 114742.15657661199 88204.1427256942 92348.9022691395 85487.359224506 72203.93785756643 91731.28883432968 86729.08562428698 75548.83663551952 85903.56034879685 1.3211230272245402 1.3357089753989346 1.026780989839725 1.0750299742428886 0.9951550189235355 0.8405232281921096 1.067840360304862 1.0096099075770344 0.8794610645794688 1.0 16.39043030592027 -5.317656923434272 1.8968302025757497 0.9759329779043444 1.3599300774818324 0.7809346510486643 0.07197267244115566 0.172279787331064 1.122546306117728 0.020798334513710135 0.07803448144930128 4.812193438085901e-06 5.317656923434272 0.38399709957748795 VLSSIEQK ddPTM_PC-9_Lapatinib_30min_R1 2 VLSSIEQK 8 0 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 ; 127.46 0.015246000000000001 66044000.0 321660.0 302510.0 327480.0 314590.0 300580.0 278930.0 337520.0 276030.0 295570.0 309100.0 False True 317073.0694147802 301809.55668115907 300555.85850935685 337725.9980414763 282900.47536301723 267000.814117588 354995.13410195673 288855.36149705783 262279.79410991713 362527.52315013984 0.8746179232396245 0.8325148779287729 0.8290566627816626 0.9315871940062547 0.7803558552045571 0.736498050679066 0.9792225732746267 0.7967818801372196 0.723475535956189 1.0 18.467731003370943 -11.174484228533434 2.6943345809617996 1.0191587798170942 0.833480845481744 0.30445836118046077 0.07632442922917392 25127455.670622457 22327172.41547191 3332336.704565162 0.020015252386304038 6.691381194516753e-12 11.174484228533434 -0.1856779343353503 VLST(ph)SPTISK ddPTM_PC-9_AZD4547_30min_R2 1 VLSTSPTISK 10 0 A0A087WX19;A0A087WX45;Q6IPM2-2;Q6IPM2-3;Q6IPM2-4;Q6IPM2;H7C427 A0A087WX19 IQCE IQ domain-containing protein E 1 VLS(0.075)T(0.453)S(0.453)PT(0.018)IS(0.001)K 90.913 0.020555 8283500.0 60045.0 53242.0 80209.0 90178.0 87719.0 70121.0 61383.0 76740.0 67122.0 68761.0 True False 79138.06098641308 70451.4352959434 79145.37625237042 69388.85533621155 75540.73099015612 65736.32278506346 66845.96808537235 64881.59630976865 70669.93188772115 66353.69831921937 1.1926699338699966 1.0617559696071548 1.1927801804145397 1.0457420926621213 1.1384554727716771 0.9906956876587979 1.0074188745860817 0.9778143186176507 1.0650488771211652 1.0 16.017889258077886 -6.761582592967787 24.999999303345916 1.006760392807409 1.1219160759393234 0.5888887737681141 0.04925722030049125 2.6843580801640967 468517.7605921571 0.01568684204697467 0.01471012273249826 1.7314797112370192e-07 6.761582592967787 0.11515568313191449 VLST(ph)SPTISK ddPTM_PC-9_Lapatinib_30min_R1 1 VLSTSPTISK 10 0 A0A087WX19;A0A087WX45;Q6IPM2-2;Q6IPM2-3;Q6IPM2-4;Q6IPM2;H7C427 A0A087WX19 IQCE IQ domain-containing protein E 1 VLS(0.023)T(0.477)S(0.477)PT(0.023)ISK 97.45200000000001 0.0092241 0.0 53242.0 42209.0 39418.0 45692.0 50322.0 48779.0 53505.0 47598.0 52505.0 36182.0 True False 52482.759316613 42111.26765381322 36177.20419788023 49052.34210404373 47362.15889685856 46692.83587940277 56275.22709802435 49809.57684504194 46591.33399783876 42436.010490515524 1.2367505500627334 0.992347470156864 0.85251190627276 1.1559131392666369 1.1160841546931946 1.1003116301387157 1.3261196433769828 1.173757294083392 1.097919749271717 1.0 15.37300141101204 -5.892712555639019 19.324715629455326 1.1511911087956492 1.0204198537949898 0.15376157403755653 0.1168079563176875 3.497105656231125 614.2807215689683 0.03333147776204571 0.049438961439304374 1.2802283622813672e-06 5.892712555639019 -0.13077125500065945 VLSTS(ph)TDLEAAVADALK ddPTM_PC-9_AZD4547_30min_R2 2 VLSTSTDLEAAVADALK 17 0 Q7Z460 Q7Z460 CLASP1 CLIP-associating protein 1 1 VLS(0.014)T(0.107)S(0.873)T(0.006)DLEAAVADALK;VLST(0.006)S(0.934)T(0.059)DLEAAVADALK 169.15 1.7089000000000002e-05 150104000.0 287840.0 461140.0 525090.0 449940.0 421630.0 514510.0 550940.0 613410.0 556250.0 467450.0 True False 379367.1325560695 610194.4869158048 518126.9635122884 346213.284503704 363093.9523635657 482337.60836472834 599972.5926877992 518621.57925951446 585652.2393931178 451084.7177807072 0.8410108292351797 1.352727021917085 1.1486245112922968 0.7675127772163056 0.804935166391698 1.0692838603306765 1.3300663246576074 1.1497210142943481 1.2983198417239 1.0 18.78303888451213 -7.01079702188233 24.18603197016263 1.205956657273692 0.9943757172227731 0.22820931900704977 0.18237280837967784 557.3275418195138 1248450.0881188435 0.07116514529195887 0.058782989759031026 9.75445429406958e-08 7.01079702188233 -0.21158094005091888 VLSTS(ph)TDLEAAVADALK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLSTSTDLEAAVADALK 17 0 Q7Z460 Q7Z460 CLASP1 CLIP-associating protein 1 1 VLS(0.001)T(0.006)S(0.985)T(0.008)DLEAAVADALK 147.75 7.842e-05 1894900.0 6782.1 9389.1 8220.2 10008.0 8053.0 6220.2 7825.2 6975.1 6701.5 6218.0 True False 7930.175577419115 10321.187797599801 8416.200743282103 9447.284206373784 6475.072458944199 5894.001761963716 7083.940406458087 6792.011015729345 6799.496759507584 7345.274178339078 1.0796296210160388 1.4051467034459482 1.145798038159167 1.286171758466614 0.8815290350956443 0.8024209333594234 0.9644215089136285 0.9246776704072824 0.9256967942134863 1.0 12.842600628179861 -6.263839840802115 24.99755894999617 0.9093878876507507 1.2357988006444525 0.7276775827463802 0.09362807733412551 102.72429755814578 1069733.2699040812 0.027167414383936134 0.032263383879260754 5.447034916600058e-07 6.263839840802115 0.32641091299370173 VLSTS(ph)TDLEAAVADALK ddPTM_PC-9_Lapatinib_30min_R1 4 VLSTSTDLEAAVADALK 17 0 Q7Z460 Q7Z460 CLASP1 CLIP-associating protein 1 1 VLS(0.001)T(0.004)S(0.989)T(0.006)DLEAAVADALK;VLS(0.014)T(0.061)S(0.863)T(0.061)DLEAAVADALK;VLST(0.032)S(0.918)T(0.05)DLEAAVADALK;VLST(0.038)S(0.897)T(0.065)DLEAAVADALK 326.09 9.410899999999997e-168 163860110.0 416741.1 876954.1 802424.0 750016.4 922634.8 856196.9 908564.0 944616.6 708191.2 672191.7000000001 True False 410798.2954930411 874923.5666613501 736451.7961662158 805175.1080373646 868367.2350338087 819579.3544794568 955604.9982822057 988506.9357284382 628427.2494720538 788379.1397058609 0.5210669268168451 1.1097751355874008 0.9341340467747297 1.021304430172734 1.1014589190649957 1.0395751399323383 1.212113499906575 1.2538471478294615 0.7971129851387442 1.0 19.58853007801119 -4.7583325815551705 24.99843482925189 1.0615749310731073 0.5210661867028286 0.6191910475077066 0.12474894054136818 56.811599095673074 457048.6329127284 0.030792526210932595 0.21292073402465517 1.744485718759321e-05 4.7583325815551705 -0.5405087443702787 VLSTS(ph)TDLEAAVADALKKPVR ddPTM_PC-9_Lapatinib_30min_R1 1 VLSTSTDLEAAVADALKKPVR 21 2 Q7Z460 Q7Z460 CLASP1 CLIP-associating protein 1 1 VLS(0.139)T(0.139)S(0.584)T(0.139)DLEAAVADALKKPVR 123.84 5.1771e-06 6541100.0 11504.0 8450.5 7273.5 5673.7 5125.6 6083.5 4697.5 4376.8 7691.8 5603.2 True False 11339.95085042477 8430.933386447168 6675.500906521937 6090.962824908362 4824.1222853173185 5823.322886331141 4940.713564955975 4580.162106293957 6825.468485755188 6571.70565420531 1.7255719362854003 1.2829140302490751 1.0157942637388526 0.9268465669959951 0.7340746130694864 0.8861204674626183 0.7518160162566556 0.6969518032754645 1.0386144548923144 1.0 12.682052148284189 -4.683627896956735 1.0398083290278906 0.8323546565539037 2.32237079439743 0.8665492113485878 0.10652760384339724 0.6802457902197586 0.522646098240666 0.033264843618221046 1.1845975488407996 2.071915803730912e-05 4.683627896956735 1.4900161378435262 VLSTSS(ph)TLTR ddPTM_PC-9_Lapatinib_30min_R1 1 VLSTSSTLTR 10 0 P16144-4;P16144-2;P16144-3;P16144;J3QRK0 P16144-4 ITGB4 Integrin beta-4 1 VLST(0.066)S(0.066)S(0.433)T(0.433)LTR 147.3 0.00014644 7994700.0 106500.0 105270.0 48509.0 30796.0 50898.0 35334.0 36416.0 31851.0 51939.0 20385.0 True False 104981.290470292 105026.25378276939 44520.77727015502 33060.840572444424 47904.27970931811 33822.847187576976 38301.442295143526 33330.91373779218 46089.08287808297 23908.5200886949 4.390957285554961 4.392837925272961 1.8621301989831898 1.3828058135675736 2.0036488888314574 1.4146775736056556 1.6019997119459641 1.3941019190707937 1.9277262961949748 1.0 14.545237211113903 -5.283368012629289 4.451840118514497 1.5723058041430444 4.4392310821730305 0.9445056866140832 0.27399105370020005 0.03480767694120485 1.7639052503919672 0.06705800213956178 0.16187556657200874 5.207532479953195e-06 5.283368012629289 2.866925278029986 VLSTSST(ph)LTR ddPTM_PC-9_AZD4547_30min_R2 1 VLSTSSTLTR 10 0 P16144-4;P16144-2;P16144-3;P16144;J3QRK0 P16144-4 ITGB4 Integrin beta-4 1 VLST(0.001)S(0.011)S(0.073)T(0.915)LTR 155.53 0.00069099 7561900.0 44854.0 62026.0 73756.0 79053.0 72984.0 50222.0 82418.0 77162.0 58161.0 51862.0 True False 59116.638978842115 82074.69151546113 72777.94724868574 60828.55220667485 62851.431395542095 47081.610400756676 89753.04233517784 65238.38590636402 61235.27172196518 50046.327165564224 1.1812383111206406 1.6399743230695043 1.4542115549842516 1.2154448818080228 1.255865014581705 0.9407605526175854 1.7933991846845243 1.303559913408653 1.2235717422256678 1.0 15.610976574995194 -8.579915966445615 2.5703676593304245 1.002000624069189 1.3540760162331638 0.18098046701834114 0.22731621723650988 0.5753147046402581 9.107403388781115 0.22004184484127565 0.059451153745172125 2.6307769832895716e-09 8.579915966445615 0.35207539216397477 VLSTSST(ph)LTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLSTSSTLTR 10 0 P16144-4;P16144-2;P16144-3;P16144;J3QRK0 P16144-4 ITGB4 Integrin beta-4 1 VLS(0.001)T(0.015)S(0.006)S(0.032)T(0.947)LTR 111.5 0.0038802 5820100.0 55846.0 58272.0 50467.0 49018.0 71817.0 55166.0 52158.0 39807.0 40117.0 43463.0 True False 65299.62479122212 64056.859053768254 51670.324677163306 46271.680378500205 57744.97439264814 52272.99784580727 47217.216648781 38762.10842900289 40703.63523109241 51342.49784708134 1.271843551237237 1.2476381504568674 1.0063850970215429 0.9012354739014827 1.1247013062090583 1.0181233877926497 0.9196517237905509 0.7549712237307207 0.7927864232925373 1.0 15.64786586525507 -3.2219308833284033 0.36266856706209993 0.8600838311239832 2.5870259381327516 0.6189165039869312 0.10147176948335598 13.194143056035504 0.5639317108051621 0.09307574378504122 12.523648204886738 0.0005998865388126253 3.2219308833284033 1.7269421070087683 VLSTSST(ph)LTR ddPTM_PC-9_Lapatinib_30min_R1 3 VLSTSSTLTR 10 0 P16144-4;P16144-2;P16144-3;P16144;J3QRK0 P16144-4 ITGB4 Integrin beta-4 1 VLS(0.007)T(0.007)S(0.007)S(0.041)T(0.938)LTR;VLST(0.003)S(0.003)S(0.018)T(0.976)LTR;VLS(0.025)T(0.015)S(0.015)S(0.085)T(0.861)LTR 115.7 0.0026951 13327600.0 234023.0 240720.0 99477.0 78082.0 120347.0 94773.0 89184.0 87181.0 125902.0 52065.0 True False 230685.78910543793 240162.62762979214 91298.38505232458 83824.41075391618 113268.42607130553 90719.77971665352 93801.51113933648 91231.74752988784 111721.59095316434 61064.365877748336 3.7777480497754437 3.932942300761804 1.4951172216396245 1.3727222013855633 1.8549021912070685 1.4856418864362844 1.5361088220768286 1.494025954720221 1.8295709674089211 1.0 15.898043120175158 -5.26202114006093 24.999983962568862 1.5338452650722638 3.855345374878054 0.9443556881201425 0.22780244973969022 9.081098395378564 390262.55171152204 0.05524870511752086 0.12730627514323692 5.4698933656132505e-06 5.26202114006093 2.3215001098057906 VLSTST(ph)DLEAAVADALK ddPTM_PC-9_Lapatinib_30min_R1 1 VLSTSTDLEAAVADALK 17 0 Q7Z460 Q7Z460 CLASP1 CLIP-associating protein 1 1 VLST(0.002)S(0.236)T(0.762)DLEAAVADALK 300.03 4.3516e-112 734480.0 1111.0 4453.9 5182.7 3111.1 3759.7 2541.1 3386.4 4837.0 2607.3 3206.9 True False 1095.1569362675525 4443.587268196798 4756.598411800542 3339.900672325362 3538.561837854599 2432.42307659342 3561.7312222175456 5061.744678336651 2313.638417913818 3761.2083920743503 0.2911715656530163 1.1814254369846569 1.2646463359551376 0.8879860736680341 0.9408045151954585 0.6467131897607806 0.9469646057694796 1.3457761843249105 0.6151316749130775 1.0 11.876980526664696 -4.751322634980372 24.98244310730963 0.9850385902164609 0.2911701371108306 0.4558082685916359 0.22610276047280783 393.637868254769 971988.7737691036 0.056872681829099776 0.7599012652041364 1.7728719347489318e-05 4.751322634980372 -0.6938684531056303 VLSTST(ph)DLEAAVADALKKPVR ddPTM_PC-9_AZD4547_30min_R2 1 VLSTSTDLEAAVADALKKPVR 21 2 Q7Z460 Q7Z460 CLASP1 CLIP-associating protein 1 1 VLS(0.232)T(0.232)S(0.232)T(0.304)DLEAAVADALKKPVR 144.57 8.1608e-05 35839000.0 13018.0 9355.6 20837.0 24103.0 18986.0 15688.0 16486.0 17863.0 13020.0 18892.0 True False 17157.453208778832 12379.614741270565 20560.687765346065 18546.425737637845 16350.121622215323 14707.026879994257 17953.222062386165 15102.683800904322 13708.210619143189 18230.596830277274 0.941135025282542 0.6790570191706817 1.1278121038362818 1.0173241123316403 0.8968505954265377 0.8067221834212749 0.9847852064047379 0.8284250889593405 0.7519342754800363 1.0 14.154074172412331 -6.516021622206609 24.369980497593026 0.8684657397103237 0.9385642900067199 0.058022473715693246 0.12617252455772737 751.876286132779 2672155.471466674 0.04194807964892387 0.043561403762335596 3.0477432479471046e-07 6.516021622206609 0.07009855029639622 VLSTST(ph)DLEAAVADALLLGDSR ddPTM_PC-9_Lapatinib_30min_R1 1 VLSTSTDLEAAVADALLLGDSR 22 0 Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460-4 CLASP1 CLIP-associating protein 1 1 VLS(0.006)T(0.018)S(0.186)T(0.791)DLEAAVADALLLGDSR 119.62 9.284299999999999e-05 0.0 922.66 1166.5 2395.1 864.52 2265.4 874.02 2550.9 2292.9 779.62 691.97 True False 909.5026992048786 1163.7990409195459 2198.184123353365 928.0996847541779 2132.1536259477643 836.6402020401317 2682.973120350441 2399.436504642985 691.8109858374453 811.5760925079323 1.1206622614945858 1.4339986745089721 2.7085373061699447 1.1435769157346225 2.6271764849048025 1.0308832526778189 3.305879935496274 2.9565145237684938 0.8524289862945704 1.0 9.664582556436246 -6.25963309581207 24.98445581645508 2.080596342218974 1.668775862719019 0.02535769130362664 0.8976508440266643 617.1415481853102 8536275.99599079 0.268301595049785 0.32892698108311913 5.500053376058688e-07 6.25963309581207 -0.41182047949995493 VLSTSTDLEAAVADALKKPVR ddPTM_PC-9_AZD4547_30min_R2 2 VLSTSTDLEAAVADALKKPVR 21 2 Q7Z460 Q7Z460 CLASP1 CLIP-associating protein 1 0 ; 103.39 0.0004516999999999999 14179400.0 34088.9 33102.4 54980.0 69158.0 61805.0 51287.0 48414.0 51976.0 46454.0 60124.0 False True 44928.46110683217 43802.10344728659 54250.92927670618 53214.691580448794 53224.44258195607 48080.01578239833 52722.75220965451 43944.30348966034 48909.463602279364 58019.077060321346 0.7743739366988015 0.7549603624639937 0.935053296699334 0.9171930040376629 0.9173610694740907 0.8286932198595721 0.9087140795921254 0.7574112811889833 0.8429893421336074 1.0 15.824239725566436 -5.246931159993582 24.52542937615119 0.8804149474362809 0.7646671216544152 0.3737701030938245 0.06340234915291437 707.8998572337083 1196663.068375426 0.016399699365391252 0.04295000122787696 5.663290507263058e-06 5.246931159993582 -0.11574782578186571 VLSTSTDLEAAVADALKKPVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLSTSTDLEAAVADALKKPVR 21 2 Q7Z460 Q7Z460 CLASP1 CLIP-associating protein 1 0 149.31 0.00036473 3208600.0 11877.0 7915.4 11556.0 14267.0 15082.0 17027.0 14208.0 21449.0 15764.0 11409.0 False True 13887.541518557207 8701.188600943808 11831.538866374043 13467.666244238071 12126.790367042888 16134.07414567959 12862.115382987846 20885.986477094048 15994.518677442 13477.361386405697 1.0304347505710763 0.6456151431630004 0.8778824376044589 0.9992806349930332 0.8997896561024846 1.1971241018997723 0.9543496693619542 1.549708869435026 1.1867692954776223 1.0 13.718250451190546 -6.762822271707798 1.054972201190131 1.2395019863303396 0.8457848901985358 0.3730788164396639 0.1801807285820605 0.4720217183678994 1.1217171074833208 0.09660521487648865 0.08741617943946027 1.7265443089602626e-07 6.762822271707798 -0.39371709613180383 VLSTSTDLEAAVADALKKPVR ddPTM_PC-9_Lapatinib_30min_R1 2 VLSTSTDLEAAVADALKKPVR 21 2 Q7Z460 Q7Z460 CLASP1 CLIP-associating protein 1 0 ; 153.92 1.4883e-05 10926000.0 110422.0 76270.0 84735.0 70260.0 63249.0 66013.0 54084.0 59307.0 68061.0 49029.0 False True 108847.36203108529 76093.40150101473 77768.41538655883 75427.15478048936 59528.818172318424 63189.777873819025 56884.20488495562 62062.61973084803 60395.253465896654 57503.59732296402 1.8928791779713088 1.32328071709397 1.3524095710009096 1.3116945424624344 1.0352190287849283 1.0988839101477261 0.9892286314797032 1.0792823861484466 1.0502865260183967 1.0 15.811364590870179 -1.522878745308169 0.4809162273386109 1.02758732060237 23.552223262561235 0.8984456076120936 0.08358789618010434 29.048350247697897 0.32478051891221504 0.04814221898060503 654.4040523681539 0.029999999998077478 1.522878745308169 22.524635941958863 VLSVAEVAAT(ph)TATPDGGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLSVAEVAATTATPDGGPR 19 0 Q147X3;Q147X3-2 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 VLSVAEVAAT(0.395)T(0.21)AT(0.395)PDGGPR 100.02 0.0011474999999999999 1766200.0 2533.3 2965.2 6982.0 7276.1 6340.0 5000.1 2029.7 5418.1 5345.0 1780.8 True False 2962.1376550442856 3259.5654596758955 7148.47735938245 6868.443706434474 5097.722512070808 4737.8859538270135 1837.4321222445424 5275.880615951477 5423.160513253459 2103.644943194956 1.4080977232524208 1.5494846077614983 3.3981387317793024 3.2650204249785983 2.4232808528650907 2.2522270068214305 0.8734516383995404 2.5079710494959384 2.5779828153970303 1.0 11.038675509293395 -7.0140497393925845 23.845590762080647 1.8222761770331597 2.4510111153862324 0.1383733650030622 0.7796489806685079 853.7317905325725 1448974.8984506691 0.31181371229126 0.2519247481343587 9.681669665387595e-08 7.0140497393925845 0.6287349383530727 VLSVAEVAATT(ph)ATPDGGPR ddPTM_PC-9_Lapatinib_30min_R1 1 VLSVAEVAATTATPDGGPR 19 0 Q147X3;Q147X3-2 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 VLSVAEVAAT(0.1)T(0.47)AT(0.43)PDGGPR 102.89 0.0018488 0.0 10740.0 7821.8 10042.0 7369.9 8162.8 6934.1 7248.8 6078.1 7568.9 5851.2 True False 10586.845630525211 7803.689102669956 9216.385523240986 7911.907031265688 7682.680152682267 6637.54470717659 7624.107395349204 6360.510715194959 6716.410777949562 6862.572123766077 1.542693532336285 1.137137644884584 1.3429928832839968 1.1529069405136905 1.1195044677309893 0.9672094642458934 1.1109693651081378 0.9268406364965684 0.9787016670746035 1.0 12.744533691191998 -1.5228787494715108 0.2997882067637111 0.9527767424036016 5.391391173324656 0.7458146621409494 0.09078542124809956 26.3283179695288 0.37517060409366304 0.0890543782534392 62.65420666495352 0.02999999971048401 1.5228787494715108 4.438614430921054 VLSVAEVAATTAT(ph)PDGGPR ddPTM_PC-9_AZD4547_30min_R2 1 VLSVAEVAATTATPDGGPR 19 0 Q147X3;Q147X3-2 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 VLSVAEVAAT(0.008)T(0.147)AT(0.844)PDGGPR 162.82 2.9637e-06 2158600.0 11773.0 14185.0 21474.0 24804.0 19321.0 20539.0 18660.0 19580.0 20205.0 20785.0 True False 15516.56910638756 18770.023847206256 21189.240729137648 19085.821017979877 16638.61265473625 19254.693083133716 20320.703850790116 16554.36090363917 21272.99505067497 20057.32347646163 0.7736111512883115 0.9358189725181382 1.0564341126573733 0.9515637039198243 0.8295529896729529 0.9599831755084447 1.0131313818933805 0.8253524416189738 1.0606098603156098 1.0 14.2918414797735 -4.771360844857611 4.971654012174943 0.9550714299068419 0.7633375934091293 0.3438306105229487 0.07711444027439289 0.19259471703447598 12.322814061565524 0.01890322753902471 0.1271726699419455 1.6929306005352212e-05 4.771360844857611 -0.19173383649771258 VLSVAEVAATTAT(ph)PDGGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLSVAEVAATTATPDGGPR 19 0 Q147X3;Q147X3-2 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 VLSVAEVAAT(0.057)T(0.292)AT(0.651)PDGGPR 126.88 7.7446e-05 1915100.0 8460.2 9402.7 10069.0 8231.4 10492.0 9660.5 9386.1 6288.9 5626.3 5747.5 True False 9892.344763433328 10336.137915720532 10309.083146895146 7770.221344558861 8436.1679174522 9153.8863736617 8496.980658520708 6123.823038640343 5708.573993586138 6789.47625281503 1.457011468201512 1.5223763263675893 1.5183915169628626 1.144450772817299 1.242535889856662 1.3482463201585462 1.2514928018192446 0.9019580908175802 0.8407974018937423 1.0 12.72908457244434 -7.133593543345544 0.5741370212048567 0.8777612441635989 1.486810343931194 0.7188221182440682 0.12476029070381879 0.491574504919002 0.3393720811789972 0.12360866137668278 0.10548590215193286 7.352016222301152e-08 7.133593543345544 0.609049099767595 VLSVAEVAATTAT(ph)PDGGPR ddPTM_PC-9_Lapatinib_30min_R1 1 VLSVAEVAATTATPDGGPR 19 0 Q147X3;Q147X3-2 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 VLSVAEVAAT(0.084)T(0.058)AT(0.857)PDGGPR 159.5 1.4270999999999998e-20 0.0 9507.5 10413.0 8759.3 10220.0 9465.5 7891.4 6227.2 8639.0 8397.9 8100.8 True False 9371.921306538035 10388.889338272807 8039.1441658758 10971.61289292057 8908.75789988901 7553.903217751881 6549.613946076388 9040.399478220035 7452.040068192553 9501.012486362499 0.9864129028343287 1.0934507615040758 0.8461355226524515 1.1547835463503424 0.9376640555600158 0.7950629712985383 0.6893595767269572 0.9515195871173082 0.7843416771516735 1.0 13.213865548760442 -6.5587648714391555 5.564421176587158 0.8333525780615869 1.0170830474851105 0.36023269185739737 0.11020534643655071 0.18932708579979213 15.351429532534636 0.0350851984659646 0.03561697344771351 2.762072847446795e-07 6.5587648714391555 0.18373046942352356 VLT(ph)PEEQLADK ddPTM_PC-9_AZD4547_30min_R2 3 VLTPEEQLADK 11 0 O75822;O75822-2;O75822-3 O75822 EIF3J Eukaryotic translation initiation factor 3 subunit J 1 VLT(1)PEEQLADK;VLT(1)PEEQLADK;VLT(1)PEEQLADK 126.32 0.0010187999999999998 29689700.0 113449.0 170074.0 104089.0 74487.0 99494.0 147391.0 160337.0 152506.0 151659.0 110348.0 True False 149523.4221142073 225047.0945216607 102708.71184945563 57315.172962678116 85680.97549145114 138174.61746999164 174606.68238607384 128939.701939244 159675.3851220149 106484.75010731736 1.404176860663285 2.1134208822845895 0.9645391640206117 0.5382477106338212 0.8046314181617576 1.29760005381744 1.6397341610897513 1.2108748136169367 1.4995141084623949 1.0 16.700287308457206 -6.988952187655669 24.618234750489208 1.3713270974901959 1.1596743931144342 0.03499294307064649 0.420930068534067 709.6876334314247 1581413.2635277174 0.16620816044871198 0.1464466189015829 1.0257648485301725e-07 6.988952187655669 -0.21165270437576167 VLT(ph)PEEQLADK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VLTPEEQLADK 11 0 O75822;O75822-2;O75822-3 O75822 EIF3J Eukaryotic translation initiation factor 3 subunit J 1 VLT(1)PEEQLADK;VLT(1)PEEQLADK;VLT(1)PEEQLADK 97.273 0.013347 15161400.0 74740.8 141867.0 97760.0 68501.3 85097.0 53396.3 84453.0 44556.4 53779.2 58469.8 True False 87392.94124191134 155950.6181936598 100090.96915686471 64663.394245211086 68422.85372392579 50596.10402918608 76453.00045322868 43386.84171140811 54565.619059749355 69069.911893318 1.265282361687303 2.2578661810736556 1.4491254789996013 0.9362020664669009 0.9906318373419728 0.7325346542693487 1.1068929778181018 0.6281583474208176 0.7900056271105245 1.0 16.075769762875353 -5.657019201642557 3.313725053703558 0.8702819809631743 1.781404029775053 0.6590802884338214 0.26046732360731095 0.12550896889821553 2.699690533068132 0.0689236366922391 0.12797238748542075 2.202829066302658e-06 5.657019201642557 0.9111220488118787 VLT(ph)PEEQLADK ddPTM_PC-9_Lapatinib_30min_R1 1 VLTPEEQLADK 11 0 O75822;O75822-2;O75822-3 O75822 EIF3J Eukaryotic translation initiation factor 3 subunit J 1 VLT(1)PEEQLADK 122.46 0.0016312000000000002 11548000.0 26111.0 48172.0 38588.0 34653.0 50706.0 44600.0 47862.0 50936.0 40119.0 41168.0 True False 25738.652351829045 48060.460693678826 35415.44359398757 37201.49721901924 47723.57277183158 42692.56196767798 50340.06016943541 53302.67251101009 35600.375748201004 48283.833947088126 0.5330697719662189 0.9953737465493299 0.7334844957175026 0.7704752124652431 0.9883965060465061 0.8841999169838637 1.0425862251245541 1.1039444914300274 0.7373146007256528 1.0 15.559252616471793 -6.257695574209735 24.99999883382669 0.9650027955803361 0.7732905557836239 0.33127511931594933 0.13931492824773203 402.5212060516348 2687914.3910068274 0.04007455196418211 0.049754593274378034 5.524645626176314e-07 6.257695574209735 -0.19171223979671215 VLT(ph)PEEQLADKLR ddPTM_PC-9_AZD4547_30min_R2 3 VLTPEEQLADKLR 13 1 O75822;O75822-2;O75822-3 O75822 EIF3J Eukaryotic translation initiation factor 3 subunit J 1 VLT(1)PEEQLADKLR;VLT(1)PEEQLADKLR;VLT(1)PEEQLADKLR 120.59 0.00015158 38855100.0 202491.0 168949.0 213553.0 206391.0 216176.0 248460.0 237562.0 242425.0 206931.0 236585.0 True False 266878.92592555203 223558.46027223463 210721.1476869487 158810.7436591632 186163.69386937865 232923.75692270373 258704.5577814253 204963.7866223052 217868.9502019908 228302.23116086915 1.1689720445066545 0.9792215307554664 0.9229920645780626 0.6956162576758175 0.8154265200246846 1.020243016191016 1.1331670149081183 0.8977739095238235 0.9543005738234476 1.0 17.80058543329418 -8.573758574933832 16.22347967900635 1.000000028929853 0.9474681371414546 0.008719579003615974 0.13182771614546682 1654.8898367087806 527686.1217095356 0.1384687398870585 0.03575245096241323 2.668341588084301e-09 8.573758574933832 -0.052531891788398344 VLT(ph)PEEQLADKLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VLTPEEQLADKLR 13 1 O75822;O75822-2;O75822-3 O75822 EIF3J Eukaryotic translation initiation factor 3 subunit J 1 VLT(1)PEEQLADKLR;VLT(1)PEEQLADKLR 84.352 0.006221 20795800.0 101886.0 88779.0 109366.0 130824.0 137031.0 119092.0 123001.0 106367.0 115694.0 98806.0 True False 119133.2874597727 97592.39240002917 111973.70021286463 123494.35541713047 110180.75923526441 112846.60587051601 111349.45482987662 103574.97895515247 117385.80587845595 116718.74565213411 1.020686838212217 0.83613297808127 0.9593463293941531 1.0580507417822176 0.9439851209817199 0.9668250394571706 0.9539980421117615 0.8873894109849757 1.0057151079082869 1.0 16.832676758597152 -5.500338431919705 24.98124974739532 0.9699032752181725 0.9207423451559078 0.07901147833179611 0.059032756363947586 1699.9157387231758 1884000.1846858598 0.015088174649892126 0.031018109447900535 3.159814357364724e-06 5.500338431919705 -0.04916093006226474 VLT(ph)PEEQLADKLR ddPTM_PC-9_Lapatinib_30min_R1 3 VLTPEEQLADKLR 13 1 O75822;O75822-2;O75822-3 O75822 EIF3J Eukaryotic translation initiation factor 3 subunit J 1 VLT(1)PEEQLADKLR;VLT(1)PEEQLADKLR;VLT(1)PEEQLADKLR 97.904 0.0020858 26416000.0 206526.0 180658.0 165074.0 150330.0 204624.0 185965.0 165061.0 146302.0 160059.0 137195.0 True False 203580.90136776972 180239.6975005942 151502.25292406738 161385.76968617926 192588.41862626254 178011.7104555883 173607.0509303242 153099.72502170948 142031.4699240087 160908.97294915377 1.2651929698917412 1.1201345344336318 0.9415401151801592 1.0029631457356711 1.1968780553159037 1.106288277110804 1.0789146667736358 0.951467915155285 0.8826820985855759 1.0 17.295885253377598 -7.757815642818596 4.069153519776506 0.9336072448590933 1.0977367099611133 0.3970127564082807 0.08879974129966589 0.23295254389479153 8.68881986425129 0.05229529476267492 0.025925006067898868 1.7465634084229646e-08 7.757815642818596 0.16412946510201998 VLT(ph)PPQAAGDGILATTANQR ddPTM_PC-9_AZD4547_30min_R2 4 VLTPPQAAGDGILATTANQR 20 0 Q96QT6;C9J9G2;Q96QT6-4;Q96QT6-2;Q96QT6-5;Q96QT6-3;K7EPF7 Q96QT6 PHF12 PHD finger protein 12 1 VLT(0.815)PPQAAGDGILAT(0.093)T(0.093)ANQR;VLT(1)PPQAAGDGILATTANQR;VLT(1)PPQAAGDGILATTANQR;VLT(1)PPQAAGDGILATTANQR 141.74 9.800799999999999e-05 27997800.0 64878.0 63235.0 80120.0 103042.0 89359.0 88470.0 74032.0 86934.0 68959.0 80098.0 True False 85507.85445376819 83674.47712217747 79057.55645052192 79287.25888303028 76953.04529861687 82937.95691439894 80620.70458101237 73500.34784458483 72604.03195741131 77293.79339993374 1.1062706420854935 1.0825510489468253 1.0228189479776484 1.02579075751635 0.9955915205305842 1.0730222087207073 1.0430424104541554 0.9509217313773066 0.9393255106751371 1.0 16.238064951647388 -1.5228787702195208 0.25420714661073296 0.974205269295873 1.8355913945548108 0.5421614242946763 0.03506803443310977 43.94605886226483 0.6014632021330885 0.04918744193100965 16.275524746370944 0.029999998277262303 1.5228787702195208 0.8613861252589378 VLT(ph)PPQAAGDGILATTANQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VLTPPQAAGDGILATTANQR 20 0 Q96QT6;C9J9G2;Q96QT6-4;Q96QT6-2;Q96QT6-5;Q96QT6-3;K7EPF7 Q96QT6 PHF12 PHD finger protein 12 1 VLT(1)PPQAAGDGILATTANQR;VLT(1)PPQAAGDGILATTANQR;VLT(1)PPQAAGDGILATTANQR 153.17 7.4483e-05 12407200.0 37959.4 39205.0 29828.2 37977.0 43930.0 34523.2 36267.8 36759.3 30118.8 29783.6 True False 44385.17668767534 43097.013303181375 30539.41741207844 35849.27181309521 35322.231854143625 32712.742617379776 32832.25142786648 35794.4073246978 30559.23047082847 35183.13091315211 1.2615470975916852 1.2249340006028544 0.86801306817928 1.0189335310034642 1.0039536259957897 0.9297848647446877 0.9331816292561153 1.017374133446355 0.8685762090435464 1.0 15.102596252123178 -5.233641354666355 12.543011233667432 0.9579580632050776 1.243373141189557 0.8193977957507595 0.05411873843004732 0.6475292818919921 290.5458352476188 0.013133795273234793 0.034398165323364156 5.839271188906887e-06 5.233641354666355 0.2854150779844794 VLT(ph)PPQAAGDGILATTANQR ddPTM_PC-9_Lapatinib_30min_R1 4 VLTPPQAAGDGILATTANQR 20 0 Q96QT6;C9J9G2;Q96QT6-4;Q96QT6-2;Q96QT6-5;Q96QT6-3;K7EPF7 Q96QT6 PHF12 PHD finger protein 12 1 VLT(1)PPQAAGDGILATTANQR;VLT(1)PPQAAGDGILATTANQR;VLT(1)PPQAAGDGILATTANQR;VLT(1)PPQAAGDGILATTANQR 181.49 1.4349e-09 26049000.0 137369.0 117168.0 120900.0 116464.6 126755.0 136207.0 114888.0 120895.0 112575.6 102116.0 True False 135410.09286961055 116896.70469478055 110960.06868749594 125029.7951985163 119299.52010991813 130381.74412402512 120836.33848869853 126512.22304889605 99896.15045437761 119766.61453898269 1.1306163524020802 0.9760374804343491 0.9264691092306002 1.0439453071274758 0.9960999613217545 1.0886317913043064 1.0089317373947115 1.0563229455543952 0.8340901246888175 1.0 16.869866281131706 -8.243470649120425 24.88013925398154 0.9170450381451268 1.024042649875473 0.3112003805570135 0.06600387985497708 812.2160649284319 1124627.825558108 0.04339910251533023 0.016325049051926468 5.708596552179333e-09 8.243470649120425 0.10699761173034628 VLT(ph)PTQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLTPTQVK 8 0 P30086 P30086 PEBP1 Phosphatidylethanolamine-binding protein 1;Hippocampal cholinergic neurostimulating peptide 1 VLT(0.673)PT(0.327)QVK 82.287 0.040791 8787800.0 61007.0 72158.0 60768.0 68771.0 87645.0 82362.0 67785.0 69366.0 61446.0 50323.0 True False 71334.28015682577 79321.36936439136 62216.93958392336 64917.98382859029 70471.59141489689 78042.7917299855 61363.91407909856 67545.21599935228 62344.53150558876 59446.16154335122 1.1999812654817943 1.3343396327876629 1.0466098730117595 1.0920466880144772 1.1854691637828516 1.3128314714327292 1.0322603257461598 1.1362418404440597 1.0487562171718001 1.0 15.859296037272202 -6.985185056586028 0.024523474322290902 1.7029056603043517e-06 2.2821454015674125 0.311792025741341 0.09232602660670239 446.01494707875986 5.112712814672203 224.3163978986772 249.85696474351624 1.0347011777270389e-07 6.985185056586028 2.282143698661752 VLT(ph)PTQVK ddPTM_PC-9_Lapatinib_30min_R1 2 VLTPTQVK 8 0 P30086 P30086 PEBP1 Phosphatidylethanolamine-binding protein 1;Hippocampal cholinergic neurostimulating peptide 1 VLT(0.718)PT(0.282)QVK;VLT(0.5)PT(0.5)QVK 94.69200000000001 0.016273 23894000.0 345710.0 320600.0 302690.0 314110.0 336610.0 329370.0 253720.0 253560.0 304880.0 212110.0 True False 340780.1120045498 319857.6703976053 277803.9966171894 337210.697240243 316811.2616007229 315283.61289897055 266856.3801385053 265341.3232662889 270541.20387127105 248772.93088119052 1.3698440212022114 1.2857414561327958 1.1166970443012691 1.3554959377846811 1.273495715464422 1.2673549802311261 1.0726905825053414 1.0666004630263055 1.087502578809415 1.0 17.924469988008013 -7.266588743258921 4.770760488866084 1.0600004562531025 1.2754591147019527 0.7233974691609009 0.06710927047180335 0.11048832303478759 7.324817550705086 0.02835027885008561 0.020014104900980618 5.412666347502794e-08 7.266588743258921 0.21545865844885026 VLTANSNPS(ph)SPSAAK ddPTM_PC-9_AZD4547_30min_R2 2 VLTANSNPSSPSAAK 15 0 Q9NV56 Q9NV56 MRGBP MRG/MORF4L-binding protein 1 VLTANS(0.021)NPS(0.619)S(0.357)PS(0.003)AAK;VLTANS(0.004)NPS(0.963)S(0.032)PS(0.002)AAK 174.24 7.0673e-05 110958000.0 69441.0 67422.0 79236.0 99379.0 91145.0 88282.0 75866.0 90245.0 78840.0 94080.0 True False 91521.79353747217 89214.8429909298 78185.27886811734 76468.70694024449 78491.09002722081 82761.71258411852 82617.92702808378 76299.7088737956 83007.32144494995 90786.28783572324 1.0081015065081174 0.9826907247530932 0.86120140752525 0.8422935749792276 0.8645698805225911 0.9116102724001107 0.9100264918594313 0.8404320816802098 0.9143156243501305 1.0 16.47018679198549 -5.1757408731115975 5.0494908367075775 0.8859057460235301 1.000591408944981 0.44837706240935304 0.04503924836790104 0.17385904524030274 7.457104814461496 0.011048231270306191 0.03106242673284844 6.672047459980148e-06 5.1757408731115975 0.11468566292145088 VLTANSNPS(ph)SPSAAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLTANSNPSSPSAAK 15 0 Q9NV56 Q9NV56 MRGBP MRG/MORF4L-binding protein 1 VLTANS(0.002)NPS(0.915)S(0.08)PS(0.004)AAK 224.55 3.0063000000000002e-24 72182000.0 21504.0 21676.0 25050.0 23378.0 25272.0 20197.0 21700.0 22154.0 20232.0 14584.0 True False 25144.202476640057 23827.850028306595 25647.287002654033 22068.20645249862 20320.13301656995 19137.833765213538 19644.418905605035 21572.48097410329 20527.85472481646 17227.96375311952 1.4594993835001029 1.38309148833634 1.488701007860549 1.2809526865009027 1.17948547534473 1.1108587201286741 1.1402635382285362 1.2521782192742945 1.1915427161900907 1.0 14.072464572877932 -6.014735045480847 2.7265571104532325 1.155992734487991 1.4379181740618852 0.7960260129906458 0.06726451445327644 0.12235408748003793 1.8312824155982157 0.02042337440928611 0.03029323281242808 9.666404274427905e-07 6.014735045480847 0.28192543957389415 VLTANSNPS(ph)SPSAAK ddPTM_PC-9_Lapatinib_30min_R1 3 VLTANSNPSSPSAAK 15 0 Q9NV56 Q9NV56 MRGBP MRG/MORF4L-binding protein 1 VLTANSNPS(0.968)S(0.031)PS(0.001)AAK;VLTANS(0.038)NPS(0.481)S(0.481)PSAAK;VLTANS(0.004)NPS(0.721)S(0.21)PS(0.064)AAK 252.52 4.3498e-42 201488200.0 116050.0 113229.0 116343.0 107376.0 108379.0 105464.0 91032.0 87097.0 99732.0 75796.0 True False 114395.10571903618 112966.82520726915 106777.72763696723 115272.7892358355 102004.3603013122 100953.55056859157 95745.19153700306 91143.84458323066 88499.13193548137 88897.23760817865 1.2868240768429873 1.270757430114747 1.2011366214504686 1.2966970891031406 1.1474412821566424 1.1356207828813762 1.0770322465924902 1.0252719548491946 0.9955217317949523 1.0 16.439850969010564 -6.964973988536695 0.7619923572684941 0.9900820830293169 1.2747852107349558 0.9257945429643806 0.030393892365528252 0.16047819126481747 0.19646793163896387 0.022391877907424754 0.017894535644704456 1.0839918362587111e-07 6.964973988536695 0.2847031277056389 VLTANSNPS(ph)SPSAAKR ddPTM_PC-9_AZD4547_30min_R2 2 VLTANSNPSSPSAAKR 16 1 Q9NV56 Q9NV56 MRGBP MRG/MORF4L-binding protein 1 VLTANSNPS(0.658)S(0.34)PS(0.002)AAKR;VLTANSNPS(0.5)S(0.5)PS(0.001)AAKR 124.2 5.321e-05 17207700.0 30161.0 28022.0 46442.0 60803.0 55662.0 36543.0 36424.0 46663.0 35987.0 43160.0 True False 39751.5706122276 37079.56349992342 45826.14873533625 46785.8077469856 47934.29209605758 34257.96043317376 39665.66543736222 39452.305559066124 37889.1993510834 41648.9815368816 0.9544428013690137 0.8902874003554732 1.1002945821077432 1.1233361782341584 1.1509115067702225 0.8225401719088176 0.9523802017160232 0.9472573902948805 0.90972691175008 1.0 15.345993596637145 -6.763166101659426 24.99999941505915 0.9247094910552311 1.0428741894546045 0.329544089503373 0.08375677401825676 62.46430628521363 904366.3047133615 0.03152746515808042 0.02925035102063631 1.7251779487089244e-07 6.763166101659426 0.11816469839937338 VLTANSNPS(ph)SPSAAKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VLTANSNPSSPSAAKR 16 1 Q9NV56 Q9NV56 MRGBP MRG/MORF4L-binding protein 1 VLTANSNPS(0.599)S(0.401)PSAAKR;VLTANSNPS(0.492)S(0.492)PS(0.016)AAKR;VLTANS(0.133)NPS(0.433)S(0.433)PS(0.001)AAKR 103.77 0.0019375 48119000.0 73076.0 43812.0 93914.0 92610.0 110077.0 113207.0 98012.0 112121.0 109574.0 73214.0 True False 85446.3234832102 48161.3658165791 96153.26593082842 87421.36194567122 88508.20204435608 107270.22563046632 88727.59381456958 109177.9425520194 111176.31245635806 86487.1186382951 0.9879658939796839 0.5568617220097101 1.111764011158227 1.0108021092861619 1.0233686060754725 1.2403029181616045 1.0259053048771871 1.2623607338408565 1.2854667169722427 1.0 16.40019765379568 -5.677940675898327 1.0742722666591284 1.1618108166200825 0.7716935455764802 0.4008442937068366 0.15343590581251249 0.5662177354408131 1.2080262954997265 0.05477488143342476 0.1791404043666149 2.099226615859652e-06 5.677940675898327 -0.3901172710436023 VLTANSNPS(ph)SPSAAKR ddPTM_PC-9_Lapatinib_30min_R1 3 VLTANSNPSSPSAAKR 16 1 Q9NV56 Q9NV56 MRGBP MRG/MORF4L-binding protein 1 VLTANSNPS(0.599)S(0.361)PS(0.04)AAKR;VLTANSNPS(0.485)S(0.485)PS(0.03)AAKR;VLT(0.001)ANS(0.001)NPS(0.801)S(0.196)PS(0.001)AAKR 107.02 0.00043758 86686000.0 137177.0 88731.0 103907.0 95933.0 86087.0 89157.0 69516.0 65998.0 95745.0 65935.0 True False 135220.83082481904 88525.54882111627 95364.16755261889 102988.23284310648 81023.53191355406 85343.96294511812 73115.19833559969 69064.50801754452 84961.1898604528 77331.77689713518 1.7485804186898029 1.1447499640266998 1.2331821584737404 1.3317711938793142 1.0477391722335512 1.1036079393163378 0.9454741798168653 0.8930935094044512 1.0986581877391242 1.0 16.238773742619607 -1.5228787452803376 0.4496748069833433 0.9949238321174365 15.451219388217998 0.7317437394047452 0.12076251621889188 48.01451024380335 0.5787992670575188 0.07738858919434148 637.1726752221733 0.029999999999999995 1.5228787452803376 14.456295556100562 VLTANSNPSS(ph)PSAAK ddPTM_PC-9_AZD4547_30min_R2 1 VLTANSNPSSPSAAK 15 0 Q9NV56 Q9NV56 MRGBP MRG/MORF4L-binding protein 1 VLTANSNPS(0.349)S(0.65)PS(0.001)AAK 210.34 2.6623e-13 10469000.0 74994.0 81544.0 100190.0 109720.0 105200.0 86294.0 93819.0 109180.0 91808.0 113260.0 True False 98840.53202789689 107901.50332016833 98861.41513701699 84425.74915710169 90594.79588418038 80898.0225383874 102168.70924851428 92308.73970680933 96660.78345025335 109294.80187366075 0.9043479683704586 0.9872519229679102 0.9045390397550267 0.772458961540491 0.8289030615463613 0.7401817941158941 0.9347993454127501 0.8445849036216155 0.8844042149597225 1.0 16.737865261636706 -5.528461419138059 24.802117683250984 0.84774860490532 0.9458238415761959 0.18366738469269817 0.07289910778530631 171.28820818841982 760978.7244426371 0.019131503270968638 0.03327045727646876 2.9616830569478323e-06 5.528461419138059 0.09807523667087592 VLTANSNPSS(ph)PSAAK ddPTM_PC-9_Lapatinib_30min_R1 1 VLTANSNPSSPSAAK 15 0 Q9NV56 Q9NV56 MRGBP MRG/MORF4L-binding protein 1 VLTANSNPS(0.006)S(0.906)PS(0.088)AAK 217.32 7.9715e-18 6548900.0 43637.0 48041.0 46030.0 49037.0 46873.0 51560.0 44342.0 40023.0 53581.0 45466.0 True False 43014.728377954256 47929.764016130255 42245.591080938284 52643.34456263658 44116.022295863644 49354.89899223041 46637.81179292767 41882.614691144896 47546.14354705643 53324.73752036309 0.8066561670655809 0.8988279407437747 0.7922325180654848 0.9872218225646905 0.8273087566350811 0.9255535289486101 0.8745999316943307 0.7854256136779146 0.8916338974739447 1.0 15.702517338774415 -12.30399298005454 1.6553369641102123 3.6222903034086325 0.8664572302861262 0.30542798618841094 0.06083473313065755 2351427.8024263424 61714.45849911605 23212342.852458242 0.01461528825116561 4.96600348444305e-13 12.30399298005454 -2.7558330731225062 VLTANSNPSS(ph)PSAAKR ddPTM_PC-9_AZD4547_30min_R2 1 VLTANSNPSSPSAAKR 16 1 Q9NV56 Q9NV56 MRGBP MRG/MORF4L-binding protein 1 VLTANSNPS(0.447)S(0.553)PSAAKR 137.39 5.9096e-06 60992000.0 49113.0 50943.0 83966.0 142240.0 99336.0 79530.0 56118.0 86329.0 73601.0 73238.0 True False 64729.91238613886 67409.32850533862 82852.55597759025 109448.7655860932 85544.91106417256 74556.97652766097 61112.39328502889 72988.83669306782 77491.39860058052 70673.95991191221 0.9158948001048477 0.9538071531488738 1.1723208389746012 1.5486434568334613 1.2104162717186846 1.054942677905533 0.86470877479059 1.0327543098482221 1.0964632333771243 1.0 16.108891126039325 -6.923688163491959 5.300135530936928 0.9957855080799646 1.1697820130159433 0.16996469593779662 0.168889810856721 0.4008588750081094 19.960219527813575 0.0684277311154368 0.059967985479091754 1.192097662795583e-07 6.923688163491959 0.17399650493597874 VLTANSNPSS(ph)PSAAKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLTANSNPSSPSAAKR 16 1 Q9NV56 Q9NV56 MRGBP MRG/MORF4L-binding protein 1 VLTANSNPS(0.249)S(0.73)PS(0.021)AAKR 71.842 0.0079347 30271000.0 29053.0 16415.0 26135.0 38523.0 41266.0 36215.0 37507.0 35652.0 33787.0 28590.0 True False 33971.09907709375 18044.572717044317 26758.157517539446 36364.681203251086 33180.223530459625 34315.82164713609 33954.06543283538 34716.172776416475 34281.07095627588 33773.140681684534 1.005861415059825 0.5342876721805753 0.7922910625854417 1.0767337733257354 0.9824441215931554 1.0160684187048632 1.0053570602999609 1.0279225466064918 1.0150394741009918 1.0 15.043588726357259 -5.683316996671843 5.791079042064893 1.0164418360802179 0.7465606684716813 0.5023902726960511 0.10881722671378062 0.14350481543426086 8.002416073197415 0.027762314754551824 0.04838363748648514 2.0733995661641574e-06 5.683316996671843 -0.26988116760853653 VLTANSNPSS(ph)PSAAKR ddPTM_PC-9_Lapatinib_30min_R1 1 VLTANSNPSSPSAAKR 16 1 Q9NV56 Q9NV56 MRGBP MRG/MORF4L-binding protein 1 VLTANSNPS(0.272)S(0.727)PS(0.002)AAKR 65.28699999999999 0.013166999999999998 11170000.0 30636.0 17348.0 22226.0 21377.0 20519.0 19433.0 14026.0 18710.0 29239.0 17573.0 True False 30199.12502204568 17307.83177185794 20398.664074841094 22949.135891581507 19312.112761906144 18601.895890535554 14752.197650254922 19579.33490421309 25945.79591968017 20610.469635449357 1.4652322608944406 0.8397592135449944 0.9897233995947398 1.1134698188589414 0.9370049835589346 0.9025459496828194 0.7157623242549315 0.949970342768767 1.2588648574535255 1.0 14.331089758420527 -4.75296711732124 24.957835583431237 0.9603056067291529 1.4652332265846373 0.5350882441381575 0.1390527961814627 256.83709096810526 756539.2836457498 0.03582241820459836 0.40393101595736475 1.7661715415950845e-05 4.75296711732124 0.5049276198554844 VLTANSNPSSPS(ph)AAK ddPTM_PC-9_AZD4547_30min_R2 1 VLTANSNPSSPSAAK 15 0 Q9NV56 Q9NV56 MRGBP MRG/MORF4L-binding protein 1 VLTANS(0.003)NPS(0.315)S(0.315)PS(0.367)AAK 205.33 7.821e-13 98131000.0 21455.0 21166.0 24873.0 25879.0 29534.0 23792.0 20564.0 21249.0 20472.0 23218.0 True False 28277.24370827702 28007.49557631072 24543.167768270498 19912.996376564322 25433.71389394856 22304.282478889807 22394.156162253385 17965.455303443767 21554.10812558367 22405.144887009195 1.2620870720042763 1.2500475099605288 1.0954255324856639 0.8887689178975203 1.135172926674327 0.9954982478967199 0.9995095445795495 0.8018450848697872 0.9620160116920748 1.0 14.45154243552408 -4.607535216074265 0.549207660377969 0.9380664862717438 1.6132768486277604 0.6211868611905894 0.08626648224392591 3.2032373418965108 0.6417248800257221 0.049699912430309905 1.4437620399287172 2.468679916453962e-05 4.607535216074265 0.6752103623560166 VLTANSNPSSPS(ph)AAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLTANSNPSSPSAAK 15 0 Q9NV56 Q9NV56 MRGBP MRG/MORF4L-binding protein 1 VLTANSNPSS(0.46)PS(0.539)AAK 194.67 1.3263e-09 7083500.0 47905.0 47426.0 52598.0 50408.0 59056.0 54203.0 57851.0 63801.0 48519.0 42884.0 True False 56014.3703331214 52134.13985248516 53852.13579902579 47583.803184940974 47484.400737043194 51360.49926107187 52370.93447503029 62126.29135274733 49228.498586070054 50658.52973044281 1.10572435937595 1.0291285619597363 1.0630418230765155 0.9393048601713739 0.9373426546271801 1.0138568871691358 1.03380289072145 1.2263737554825453 0.9717711676201019 1.0 15.62851758566856 -7.537654479629097 24.999879517628255 1.0854611236231528 1.011736439653727 0.06122930252170322 0.07914486853835616 472.31015686249697 799118.0737714492 0.03683893674471895 0.02127961271356131 2.899649602646322e-08 7.537654479629097 -0.07372468396942589 VLTELLEQER ddPTM_PC-9_Lapatinib_30min_R1 1 VLTELLEQER 10 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 0 96.665 0.02508 1886700.0 7293.8 7230.8 8097.3 7722.9 9060.3 8063.6 5605.0 7016.7 7706.7 7753.4 False True 7189.7890744808965 7214.057526859028 7431.5712504819 8290.867828839164 8527.390967235158 7718.738625169684 5895.199474524373 7342.72149772272 6838.690290851232 9093.564859243897 0.7906458232573387 0.7933145733849041 0.8172340952654527 0.9117291136282195 0.9377390604485318 0.8488132811109101 0.6482825564862734 0.8074634767968484 0.7520362362511206 1.0 13.150630255268547 -9.546844847142903 14.0543302783636 1.000006078680117 0.8143044355002922 0.35239310262055834 0.07642958447032014 0.0 0.0 0.08147394320280028 0.019760333738865862 2.838933063674261e-10 9.546844847142903 -0.18570164317982485 VLTLSDDLER ddPTM_PC-9_AZD4547_30min_R2 1 VLTLSDDLER 10 0 P55010 P55010 EIF5 Eukaryotic translation initiation factor 5 0 114.97 0.0053602 2598300.0 9898.6 10290.0 11150.0 18359.0 12928.0 11404.0 11611.0 11173.0 9501.0 12476.0 False True 13046.148896329565 13616.041268082652 11002.143714719426 14126.61619372248 11133.170353523643 10690.90607722172 12644.356506512535 9446.469579997989 10003.203463324071 12039.219037398852 1.0836374731452902 1.1309737970366291 0.9138585883803728 1.1733831031597066 0.924741905512256 0.8880066093997702 1.0502638474500607 0.784641391659484 0.8308847469466196 1.0 13.555454189635917 -6.396035591381885 7.291205690283532 0.9061443873454742 1.0675050529428878 0.4132744966707992 0.09459797349561713 0.2700046210770437 14.822415564771921 0.029335242621687952 0.03324688084182982 4.0175788456313913e-07 6.396035591381885 0.16136066559741358 VLTLSDDLER ddPTM_PC-9_Lapatinib_30min_R1 2 VLTLSDDLER 10 0 P55010 P55010 EIF5 Eukaryotic translation initiation factor 5 0 ; 98.249 0.022265 6654400.0 26604.0 27006.0 27035.0 24734.0 25532.0 28444.0 24090.0 22697.0 26757.0 24070.0 False True 26224.62208142391 26943.469266243683 24812.28665811792 26553.02087020522 24030.25795784334 27227.516426202503 25337.26232672474 23751.585479472193 23743.344896298848 28230.46742874105 0.9289474978627164 0.9544110218597694 0.8789187327751036 0.9405802768668278 0.8512171475197915 0.9644727454453179 0.8975147999472805 0.8413458097860268 0.8410539058990598 1.0 14.784965396099853 -5.1462376596240755 0.7554840533550427 0.8937912414921371 0.9563922610935429 0.04266322048464233 0.052122129191514106 5.026033407589721 3.0836075558436677 0.02205714964337104 0.24412799513042935 7.14105438136671e-06 5.1462376596240755 0.06260101960140585 VLTTS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VLTTSPSR 8 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 VLT(0.088)T(0.088)S(0.813)PS(0.011)R 80.455 0.019275 35493000.0 108020.0 113090.0 177290.0 182160.0 221080.0 173200.0 165940.0 185590.0 161600.0 146670.0 True False 126305.65250774998 124316.82781422726 181517.2659760695 171954.16577068856 177760.96103605902 164117.08709882575 150220.96189843808 180718.4591488597 163963.09428283622 173260.10996091866 0.7289944150228236 0.7175155772570427 1.0476575711340212 0.9924625224437138 1.025977422478582 0.9472294986759777 0.8670256640857644 1.0430471225582356 0.9463407031186837 1.0 17.402580012455452 -5.253160568424649 24.953168830632865 0.9816058485096638 0.7232549544658811 0.8056104031349784 0.05116911292968271 245.8408708289056 740984.9634879138 0.013428329497679175 0.03424646527998879 5.5826375392729e-06 5.253160568424649 -0.25835089404378275 VLVQNAAGS(ph)QEK ddPTM_PC-9_Lapatinib_30min_R1 1 VLVQNAAGSQEK 12 0 Q9Y490 Q9Y490 TLN1 Talin-1 1 VLVQNAAGS(1)QEK 125.61 0.00028788 3708100.0 31283.0 34819.0 27765.0 30067.0 29833.0 25978.0 21293.0 27068.0 28738.0 20831.0 True False 30836.89868340041 34738.37874477299 25482.26887599941 32278.227480571713 28078.281593934676 24866.981497675744 22395.447352550844 28325.678096592215 25501.22381544405 24431.610594437236 1.262172158655049 1.4218620017086583 1.0430040531917038 1.3211665827680248 1.1492603602779974 1.0178199837278692 0.9166586568652171 1.1593864427031106 1.0437798898632722 1.0 14.576461352447172 -6.550498275773267 3.5783794118806047 1.0314184511359195 1.2574009108312378 0.5288034002086687 0.10417353121572664 0.19616367849125155 5.354080076076076 0.03544689788558181 0.036886614787923835 2.8151511917646187e-07 6.550498275773267 0.22598245969531838 VLY(ph)T(ph)NRAQAY(ph)MK ddPTM_PC-9_Lapatinib_30min_R1 1 VLYTNRAQAYMK 12 1 H0YDB4;C9JPY5;E9PIS6;C9J1D2;A8MTE9;J3KR69;Q9H892;Q9H892-2 H0YDB4 TTC12 Tetratricopeptide repeat protein 12 3 VLY(1)T(1)NRAQAY(1)MK 61.161 0.030713999999999998 0.0 4960.8 5853.6 5124.2 3778.6 5391.4 5971.7 5147.1 5022.6 4965.4 4725.7 True False 4890.058082300699 5840.04634884411 4702.908055984015 4056.490849040086 5074.2884519002255 5716.30431171261 5413.591653046277 5255.968331902764 4406.1443640199695 5542.530948400558 0.8822788952963543 1.053678617803552 0.8485127281681957 0.7318842035894616 0.9155182892329259 1.0313527096068265 0.9767363869404302 0.94829751621315 0.7949697358553275 1.0 12.43632920550196 -6.523656251814581 24.999957089562823 0.9514429994200025 0.881166073697575 0.11446630749542974 0.09326843505602114 67.74778709287516 2178255.07727141 0.032708712170648094 0.032992122535140896 2.994633979892556e-07 6.523656251814581 -0.0702769257224275 VMAIVRIDTQNNPVY(ph)QVSFSPQDN ddPTM_PC-9_AZD4547_30min_R2 1 VMAIVRIDTQNNPVYQVSFSPQDN 24 1 E9PRV3 E9PRV3 CFAP57 1 VMAIVRIDT(0.005)QNNPVY(0.766)QVS(0.134)FS(0.095)PQDN 49.089 0.021628 9144800.0 5201.1 5213.3 11864.0 16843.0 15706.0 11970.0 8332.0 13898.0 11562.0 14748.0 True False 6854.941610399416 6898.397273362028 11706.67560820011 12960.106571755972 13525.493005294113 11221.514007746762 9073.531858777236 11750.383444268498 12173.14371570918 14231.677008941833 0.48166787414388496 0.4847213205462526 0.8225787868038846 0.9106521011974255 0.9503794244905909 0.7884885246268749 0.6375588662584382 0.8256499523482492 0.8553555359681599 1.0 13.796818053355583 -5.267372166992497 5.918312180661548 0.839575446354422 0.48018168768439834 0.7104469202760132 0.09327069242237859 0.0822065331286985 12.769091936860821 0.0260232191245759 0.06138067216046901 5.402911240967327e-06 5.267372166992497 -0.3593937586700237 VMGT(ph)IMHPSDS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VMGTIMHPSDSR 12 0 F8VVR8;Q96LU7 F8VVR8 MYRFL Myelin regulatory factor-like protein 2 VMGT(0.992)IMHPS(0.017)DS(0.992)R 60.364 0.03864 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 VMIGS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 VMIGSPK 7 0 Q68CZ2;Q68CZ2-2 Q68CZ2 TNS3 Tensin-3 1 VMIGS(1)PK 82.645 0.022177000000000002 47858000.0 738640.0 660400.0 562970.0 618100.0 607060.0 581780.0 546790.0 500170.0 570280.0 416120.0 True False 728106.8581500127 658870.8843748537 516684.77972704306 663557.1359211559 571353.9243258805 556898.6255954196 575100.1107359827 523409.7241603567 506049.0610853725 488045.78755495313 1.4918822715338549 1.350018586730791 1.0586809535137423 1.359620660277578 1.170697379006774 1.1410786442505945 1.178373270297364 1.0724602844798075 1.0368884928207525 1.0 18.89665697956037 -1.5228787452803376 0.2371616523673401 1.0189435269753642 3.517551538996464 0.6780044882666895 0.08769794970228224 31.80361204804227 0.42256747314574955 0.12492732664269549 31.154520287676096 0.029999999999999995 1.5228787452803376 2.4986080120210996 VMIYQDEVKLPAKLS(ph)ISK ddPTM_PC-9_AZD4547_30min_R2 1 VMIYQDEVKLPAKLSISK 18 2 Q6NZI2 Q6NZI2 PTRF Polymerase I and transcript release factor 1 VMIYQDEVKLPAKLS(0.93)IS(0.07)K 66.809 0.012259 4758700.0 25595.0 17441.0 24743.0 36133.0 32161.0 22199.0 23132.0 22791.0 22855.0 28048.0 True False 33733.67759092752 23078.46217265592 24414.891653210994 27803.09509928508 27696.000289269312 20810.89302071598 25190.7031873782 19269.174635078685 24063.068640592737 27066.04805714678 1.2463466228871987 0.8526720311708772 0.902048633094193 1.0272314244245082 1.0232746291882902 0.7688929309804011 0.9307122759181905 0.7119315902489379 0.8890499488431556 1.0 14.724196633021304 -6.749175046443357 24.99980420459141 0.8465252524824466 0.9964818065443257 0.26619286705785894 0.1225917047774073 309.1282533816034 630130.7448134474 0.03933087940473418 0.039055716727394336 1.7816605078147424e-07 6.749175046443357 0.14995655406187913 VMIYQDEVKLPAKLS(ph)ISK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VMIYQDEVKLPAKLSISK 18 2 Q6NZI2 Q6NZI2 PTRF Polymerase I and transcript release factor 1 VMIYQDEVKLPAKLS(0.963)IS(0.037)K 54.223 0.038771 4661200.0 17672.0 9895.4 12838.0 22361.0 19546.0 21570.0 19090.0 26848.0 22813.0 16001.0 True False 20663.52056209 10877.749915579672 13144.106608386117 21108.185665340134 15716.101612135011 20438.831228185172 17281.657000368665 26143.268447807408 23146.596967044177 18901.854636153683 1.093200691670053 0.5754858517837578 0.6953871385321794 1.1167256373333012 0.8314581777639288 1.081313533598534 0.9142836686149275 1.3831059941495387 1.2245675047554092 1.0 14.206240177123293 -6.9084731641970345 0.8842854231953876 1.1983511438305565 0.8101891750826424 0.31957667334562945 0.1906458740968257 0.6342665412269726 1.051163740226793 0.12756293961810383 0.10220845491878648 1.2346016009700247e-07 6.9084731641970345 -0.3881619687479141 VMLGET(ph)NPADSKPGTIR ddPTM_PC-9_AZD4547_30min_R2 1 VMLGETNPADSKPGTIR 17 1 Q32Q12;P22392-2;J3KPD9;P22392;E7ERL0;O60361;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1;NME2P1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Putative nucleoside diphosphate kinase;Nucleoside diphosphate kinase A 1 VMLGET(0.998)NPADS(0.002)KPGT(0.001)IR 69.256 0.010556999999999999 15743000.0 60769.0 50563.0 67986.0 99213.0 77386.0 71839.0 64458.0 67505.0 63325.0 70606.0 True False 80092.27792627756 66906.50093664363 67084.46121873672 76340.97567556998 66642.28967959306 67346.89597347708 70194.63712830812 57073.65336058034 66672.2302194502 68134.10543079366 1.175509349097278 0.9819825256912347 0.9845944376106456 1.1204517208068776 0.9781047136119533 0.9884461760767347 1.0302422947287013 0.8376664373843166 0.9785441490410651 1.0 16.056089518741665 -6.851657601517176 1.0140541711734972 0.9420888855543492 1.0555478973827346 0.2712888140463976 0.07325628281525064 0.712910508321609 1.554965501377978 0.043150590227410315 0.0358300708826338 1.407156491405619e-07 6.851657601517176 0.11345901182838536 VMLGET(ph)NPADSKPGTIR ddPTM_PC-9_Lapatinib_30min_R1 1 VMLGETNPADSKPGTIR 17 1 Q32Q12;P22392-2;J3KPD9;P22392;E7ERL0;O60361;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1;NME2P1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Putative nucleoside diphosphate kinase;Nucleoside diphosphate kinase A 1 VMLGET(1)NPADSKPGTIR 110.6 0.0037927 0.0 22172.0 18888.0 19159.0 16161.0 15534.0 18363.0 17970.0 17386.0 20802.0 12963.0 True False 21855.82321415318 18844.265996475267 17583.820975878712 17349.5338515156 14620.320661019057 17577.657296243742 18900.3986721147 18193.81703071347 18459.059705228865 15203.637277888236 1.437539110850777 1.239457746330338 1.1565535703388656 1.141143631251207 0.9616330877797552 1.1561481621117216 1.243149802028159 1.1966752888253966 1.2141212900465093 1.0 13.892128891048882 -4.737908422308419 1.775019754890769 1.1382733994112069 1.560583216975657 0.5501444557866477 0.08423183732604875 0.8376634102963251 2.4719852852470807 0.024479553230939227 0.6235960637908705 1.8284857399216936e-05 4.737908422308419 0.4223098175644502 VMLGETNPADSKPGTIR ddPTM_PC-9_AZD4547_30min_R2 2 VMLGETNPADSKPGTIR 17 1 Q32Q12;P22392-2;J3KPD9;P22392;E7ERL0;O60361;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1;NME2P1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Putative nucleoside diphosphate kinase;Nucleoside diphosphate kinase A 0 ; 118.71 0.00049474 21829600.0 38096.0 30067.0 43385.0 51656.0 50031.0 39527.0 39205.0 46479.0 27927.0 34157.0 False True 50209.7355539744 39785.56975776882 42809.68655274459 39747.50727724437 43085.059247922414 37055.37044145414 42694.16904985136 39296.73853116676 29403.164205899517 32961.173826581646 1.523299376962194 1.2070434738487261 1.298791322723482 1.2058887067058839 1.307145779291887 1.1242127066351841 1.2952866689298703 1.192212957521427 0.8920545233188036 1.0 15.008480000821597 -1.5228787452803376 0.1085584395939579 0.8513773687997446 2.513857310563765 0.5684500324749443 0.10900793358207642 88.01638776704166 0.671087869449006 1.044669863706933 21.889954770606938 0.029999999999999995 1.5228787452803376 1.6624799417640206 VMLGETNPADSKPGTIR ddPTM_PC-9_Lapatinib_30min_R1 4 VMLGETNPADSKPGTIR 17 1 Q32Q12;P22392-2;J3KPD9;P22392;E7ERL0;O60361;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1;NME2P1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Putative nucleoside diphosphate kinase;Nucleoside diphosphate kinase A 0 ;;; 190.34 1.4819e-08 74767400.0 150813.0 160351.0 143855.0 148621.0 142457.0 126458.0 143650.0 124844.0 144365.0 131688.0 False True 148662.37896428292 159979.71711143575 132027.7971963585 159551.08412512217 134077.95934123814 121049.6861279959 151087.49411515176 130644.70800542901 128105.09346915518 154450.09533676988 0.9625269485275023 1.0358019965129113 0.8548249640667376 1.0330267765599617 0.8680989095467282 0.7837462700431085 0.9782285584590533 0.8458700379599343 0.829427092225674 1.0 17.236781235929023 -6.287613251389526 24.25868361851143 0.8761978592410113 0.9677977921798777 0.23193571594676154 0.07689437068328318 723.516425258037 670573.0360912911 0.022971697579654865 0.026057164199180367 5.156876711672826e-07 6.287613251389526 0.09159993293886637 VMPNS(ph)PQNGVLVK ddPTM_PC-9_AZD4547_30min_R2 6 VMPNSPQNGVLVK 13 0 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 VMPNS(1)PQNGVLVK;VMPNS(1)PQNGVLVK;VMPNS(1)PQNGVLVK;VMPNS(1)PQNGVLVK;VMPNS(1)PQNGVLVK;VMPNS(1)PQNGVLVK 115.09 0.00029471 114579200.0 283302.0 248087.0 340898.0 410959.0 336837.0 325396.0 275033.0 348388.0 267747.0 295855.0 True False 373386.14295233303 328276.27114429756 336377.469781204 316218.75180325727 290072.9967798451 305048.93668043177 299510.4041904799 294552.63975980785 281899.5598036657 285497.2065012541 1.3078451713351278 1.1498405717075046 1.1782163261892595 1.1076071660332278 1.016027443261764 1.0684830875187277 1.049083484426893 1.03171811510707 0.9873986623488289 1.0 18.123117103784985 -1.5228787452824577 0.33364252225944463 1.00078264671751 4.109642552289702 0.8963023152273869 0.03033860712579721 17.46013020988311 0.2481942450037289 0.027268696764969336 33.59657534854657 0.029999999999853547 1.5228787452824577 3.108859905572192 VMPNS(ph)PQNGVLVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 VMPNSPQNGVLVK 13 0 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 VMPNS(1)PQNGVLVK;VMPNS(1)PQNGVLVK;VMPNS(1)PQNGVLVK;VMPNS(1)PQNGVLVK;VMPNS(1)PQNGVLVK 115.09 0.00028261 93113800.0 312449.0 287222.0 332107.0 331635.0 354214.0 312770.0 331850.0 327483.0 297113.0 249072.0 True False 365340.44455095305 315735.5019759309 340025.6904028108 313054.5661251761 284808.3094464742 296367.79059988295 300414.7656140568 318886.9182469206 301457.715542427 294226.78194713255 1.2416967691832974 1.073102522776676 1.155658530309819 1.0639907218963722 0.9679890714287501 1.0072767293262077 1.0210313406073146 1.0838133637481686 1.0245760550669167 1.0 18.1665690480987 -1.5228787653835343 0.556011468245243 1.0218071395130797 10.66530581028054 0.6797943123231254 0.04397227241846409 87.557737889707 0.7867390351052618 0.022735963380793117 1010.7036201112641 0.0299999986113204 1.5228787653835343 9.64349867076746 VMPNS(ph)PQNGVLVK ddPTM_PC-9_Lapatinib_30min_R1 2 VMPNSPQNGVLVK 13 0 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 VMPNS(1)PQNGVLVK;VMPNS(1)PQNGVLVK 147.56 0.00011049 44930000.0 187991.0 135089.0 164727.0 124402.0 149644.0 151825.0 127124.0 118840.0 149463.0 101038.0 True False 185310.21386667245 134776.2097203434 151183.78192460816 133550.93807290643 140842.23413142373 145331.7986713611 133705.85869749097 124361.74024674957 132628.90302483528 118502.28367532766 1.5637691369255382 1.137330062681349 1.2757879193182573 1.1269904168160088 1.1885191556080306 1.2264050460794569 1.1282977386648347 1.0494459379996055 1.119209680281029 1.0 16.85455533622131 -2.558243971513029 1.362102526511934 1.1391118138916856 199.99999999307693 0.7200350006316322 0.07831988034751193 371.7935387822718 1.922902989510588 0.022266537707678773 229748.31253776347 0.0027653877104845434 2.558243971513029 198.86088817918525 VMQEQGTHPK ddPTM_PC-9_AZD4547_30min_R2 2 VMQEQGTHPK 10 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 72.096 0.021343 13318500.0 113645.0 112292.0 133550.0 177260.0 155100.0 133550.0 114092.0 143120.0 121451.0 131412.0 False True 149781.74603715437 148588.19301025628 131779.03973998028 136395.44563969973 133567.0422208787 125199.09738801862 124245.96697450914 121004.09257042075 127870.65191286935 126811.30587869958 1.181138739951365 1.1717267003967864 1.0391742189456872 1.0755779596668438 1.0532739277098941 0.9872865555676628 0.9797704243607088 0.9542058709352487 1.008353719148536 1.0 16.952323849314837 -4.946405966378378 0.5269083577508489 0.9775347215473265 1.3184915426799986 0.8579026127164935 0.027912226564435195 1.2710191459541598 0.3060877560939117 0.01750106877979641 0.2620313382068513 1.1313423215257413e-05 4.946405966378378 0.3409568211326721 VMQEQGTHPK ddPTM_PC-9_Lapatinib_30min_R1 2 VMQEQGTHPK 10 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 73.95100000000001 0.01806 16155900.0 99734.0 89028.0 90379.0 89433.0 95746.0 82111.0 86395.0 81001.0 90712.0 71281.0 False True 98311.77487102445 88821.86113586396 82948.38749302902 96010.201159742 90114.40852387852 78599.3039400898 90868.1103660185 84764.60216868868 80495.05932029232 83601.82587403795 1.1759524848075666 1.0624392494691561 0.992183922131157 1.1484223000631544 1.0779000049550713 0.9401625277719962 1.0869153803282787 1.0139085035822384 0.9628385322776734 1.0 16.351246830834725 -1.5228787452803376 0.2586258242741011 0.9933807081853787 1.9395346690840771 0.36178584353326515 0.05897644926803585 64.21946228603852 0.884513237265577 0.07508805412997444 26.731604986671567 0.029999999999999995 1.5228787452803376 0.9461539608986984 VMS(ph)PENFPTASVEGK ddPTM_PC-9_AZD4547_30min_R2 1 VMSPENFPTASVEGK 15 0 H3BRU9;H3BSP3;H3BTW3;Q3L8U1-2;Q3L8U1-3;Q3L8U1 H3BRU9 CHD9 Chromodomain-helicase-DNA-binding protein 9 1 VMS(1)PENFPTASVEGK 100.41 0.0016495999999999998 4487900.0 16009.0 15756.0 22585.0 28893.0 20734.0 21384.0 19122.0 24203.0 18570.0 21609.0 True False 21099.52899211404 20848.81887462684 22285.508143223164 22232.165242400115 17855.441994891626 20046.855099553617 20823.82095577752 20462.982479610775 19551.572288593623 20852.475487267704 1.0118476823050186 0.9998246437146948 1.0687224237156137 1.0661643149262943 0.8562744507621632 0.9613657194702859 0.9986258450941385 0.9813214978770867 0.9376139682087914 1.0 14.347931041934494 -6.209959626482359 24.999637066820156 0.9573455515886062 1.0363017470863065 0.45697347405552424 0.04311688250177333 346.76395605235075 168395.4415133585 0.013209736393305393 0.017053677296188202 6.166523253306478e-07 6.209959626482359 0.07895619549770028 VMS(ph)PENFPTASVEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VMSPENFPTASVEGK 15 0 H3BRU9;H3BSP3;H3BTW3;Q3L8U1-2;Q3L8U1-3;Q3L8U1 H3BRU9 CHD9 Chromodomain-helicase-DNA-binding protein 9 1 VMS(0.986)PENFPT(0.014)ASVEGK;VMS(0.999)PENFPT(0.001)ASVEGK 68.44 0.02447 8621600.0 59751.0 63995.0 66320.0 68381.0 74802.0 65918.0 73372.0 65554.0 60752.0 53332.0 True False 69865.66416395654 70348.00067177892 67901.32032000058 64549.83426419316 60145.08507064997 62461.14403799297 66421.67299272129 63833.276960204326 61640.38306850778 63000.66942412031 1.1089670126141218 1.1166230663073817 1.0777872829078863 1.0245896568121187 0.9546737458574202 0.9914361959792005 1.0543010669548731 1.0132158522075203 0.9784083825132859 1.0 15.94307953784022 -5.701422839061381 2.5878510467914686 1.001010086237116 1.111003467252701 0.7842072942018528 0.024407934882625017 0.13310659696995802 1.807093991535764 0.007762844098651619 0.014798459367888346 1.9887361170140546e-06 5.701422839061381 0.10999338101558487 VMS(ph)PENFPTASVEGK ddPTM_PC-9_Lapatinib_30min_R1 1 VMSPENFPTASVEGK 15 0 H3BRU9;H3BSP3;H3BTW3;Q3L8U1-2;Q3L8U1-3;Q3L8U1 H3BRU9 CHD9 Chromodomain-helicase-DNA-binding protein 9 1 VMS(0.999)PENFPT(0.001)ASVEGK 91.616 0.0033898000000000005 3155300.0 40217.0 43345.0 46187.0 41691.0 42817.0 43618.0 38870.0 40620.0 46123.0 37976.0 True False 39643.49820510548 43244.637315608874 42389.68314697585 44757.09521709897 40298.58824146087 41752.55981852415 40882.498407629304 42507.353490600566 40928.14204327812 44540.101000160736 0.8900630513828969 0.9709146666607876 0.9517195110721206 1.0048718842585798 0.9047709218556879 0.9374150233375868 0.9178806848121375 0.9543614077221596 0.9189054610165887 1.0 15.442817209167425 -6.322579110570213 24.999999151841862 0.9354829223147313 0.9553829914879998 0.037215089627075315 0.03608458484698517 705.1245783113148 288322.68007917015 0.010716801317724374 0.012151720661585645 4.7579611263616197e-07 6.322579110570213 0.019900069173268475 VMS(ph)SPS(ph)AMK ddPTM_PC-9_AZD4547_30min_R2 1 VMSSPSAMK 9 0 A0A494C142;Q99728-3;Q99728-2;Q99728 A0A494C142 BARD1 BRCA1-associated RING domain protein 1 2 VMS(0.92)S(0.081)PS(0.999)AMK 51.193000000000005 0.034645 1388700.0 0.0 419.78 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 555.4656757546877 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 VMTIPYQPMPAS(ph)SPVICAGGQDR ddPTM_PC-9_AZD4547_30min_R2 2 VMTIPYQPMPASSPVICAGGQDR 23 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 VMTIPY(0.007)QPMPAS(0.535)S(0.457)PVICAGGQDR;VMTIPYQPMPAS(0.643)S(0.357)PVICAGGQDR 103.86 1.984e-06 15032500.0 59963.0 52411.0 86191.0 148119.0 113333.0 116242.0 65143.0 117213.0 76326.0 94038.0 True False 79029.98669211916 69351.83079703404 85048.05102380099 113972.45296573795 97598.66921997939 108973.3693641184 70940.60080128726 99100.42413678537 80360.43653738272 90745.75824293954 0.8708945544379544 0.7642432234834508 0.9372124126850649 1.2559535031997549 1.0755177003281366 1.2008646076038167 0.7817511493084779 1.092066737394812 0.8855558440786421 1.0 16.469542587893123 -5.522611248248084 24.999996174028386 1.0468651873898178 0.825858586368794 0.3154958433475986 0.13214578556842646 10.346859619249814 967009.0758648296 0.03599196248989226 0.06322825456566634 3.0018483732168093e-06 5.522611248248084 -0.22100660102102387 VMTIPYQPMPAS(ph)SPVICAGGQDR ddPTM_PC-9_Lapatinib_30min_R1 1 VMTIPYQPMPASSPVICAGGQDR 23 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 VMTIPYQPMPAS(0.5)S(0.5)PVICAGGQDR 94.76700000000001 7.0195e-06 6575400.0 22423.0 23991.0 30957.0 21773.0 20800.0 23940.0 17925.0 18982.0 21581.0 15772.0 True False 22103.24390812542 23935.450313502657 28411.834957475734 23374.259052598783 19576.584894373387 22916.142006865713 18853.068792301397 19863.97301719791 19150.320521995214 18498.169185131013 1.1948881906590083 1.2939361768159292 1.5359268624439553 1.2635985117590562 1.0582985104336278 1.238832977335179 1.0191856612196875 1.0738345410509458 1.0352549125449888 1.0 14.17509486984581 -6.142549973694445 4.184404891256302 1.080608682477145 1.3450425132321349 0.6042982542791562 0.1004288983749913 0.16645823811980323 4.89705566893236 0.03108190584006948 0.040990354985696975 7.201948745938291e-07 6.142549973694445 0.26443383075498983 VMTIPYQPMPASS(ph)PVICAGGQDR ddPTM_PC-9_AZD4547_30min_R2 4 VMTIPYQPMPASSPVICAGGQDR 23 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 VMTIPYQPMPAS(0.251)S(0.749)PVICAGGQDR;VMTIPYQPMPAS(0.262)S(0.738)PVICAGGQDR;VMTIPYQPMPAS(0.432)S(0.567)PVICAGGQDR;VMTIPYQPMPAS(0.066)S(0.934)PVICAGGQDR 102.28 2.0782e-06 30434100.0 71866.0 70870.0 106285.0 181161.0 138919.0 118228.0 92078.0 133396.0 102459.0 119213.0 True False 94717.89309433883 93777.34156161483 104875.59145461462 139397.1303595489 119632.4947664875 110835.18447016564 100272.76362127827 112782.7133351301 107874.77356580572 115039.38915561324 0.8233518431344796 0.8151759345206767 0.9116494117745175 1.2117339233346158 1.0399263734325048 0.9634542158446218 0.871638526223742 0.980383450946262 0.9377203265560113 1.0 16.811768394821556 -5.5242629022553436 24.99663084606053 0.9997444729420565 0.8303010461921957 0.4356278265525926 0.08293443083405933 44.06509979002902 795771.5662755854 0.024784596326260424 0.04335743860603402 2.990453802959184e-06 5.5242629022553436 -0.1694434267498608 VMTIPYQPMPASS(ph)PVICAGGQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VMTIPYQPMPASSPVICAGGQDR 23 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 VMTIPYQPMPAS(0.143)S(0.857)PVICAGGQDR 117.03 1.3602e-08 20567000.0 37111.0 38814.0 45893.0 43295.0 59645.0 41155.0 49554.0 42328.0 39473.0 37674.0 True False 43393.159324339176 42667.19740721035 46987.26317017172 40869.32151428384 47957.990415215056 38996.75935076314 44859.88638010836 41216.93485022319 40050.217949420716 44503.99797278007 0.9750395762394131 0.9587272908224299 1.05579869922946 0.9183292148107839 1.0776108349759397 0.8762529464120209 1.0079967738526763 0.9261400487082679 0.8999240466871445 1.0 15.441647324536818 -6.774243280869188 24.99965473969148 0.9415674210647543 0.9938540208631914 0.18926083958792905 0.056753514613747384 407.0062658842108 794675.6758982863 0.018742047914223806 0.01663464162221523 1.6817317332506983e-07 6.774243280869188 0.05228659979843708 VMTIPYQPMPASS(ph)PVICAGGQDR ddPTM_PC-9_Lapatinib_30min_R1 4 VMTIPYQPMPASSPVICAGGQDR 23 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 VMTIPYQPMPAS(0.266)S(0.734)PVICAGGQDR;VMTIPYQPMPAS(0.13)S(0.87)PVICAGGQDR;VMTIPYQPMPAS(0.291)S(0.709)PVICAGGQDR;VMTIPYQPMPAS(0.403)S(0.597)PVICAGGQDR 118.61 1.2181e-08 20272900.0 130692.0 117349.0 154025.0 115597.0 123286.0 142843.0 105842.0 127936.0 134890.0 94954.0 True False 128828.30811402232 117077.28560040124 141361.6590536941 124098.38900028793 116034.55986960183 136733.93787329647 111321.98087111664 133880.37361333048 119697.26774532853 111366.67238174811 1.156794087125261 1.0512775779012056 1.2693353947860426 1.1143225019321528 1.0419145816968733 1.2277814803031306 0.9995986994163004 1.2021583365121014 1.0748033068189773 1.0 16.76495803042433 -14.522878717954855 0.2047430755601677 0.399409038420098 1.146472437924974 0.1922292276606895 0.08209217472879882 240.8173146450673 2.385564642707506 59.09094557684491 0.17642520844965856 3.0000001887577517e-15 14.522878717954855 0.747063399504876 VMVLDFVTPTPLGTR ddPTM_PC-9_Lapatinib_30min_R1 4 VMVLDFVTPTPLGTR 15 0 Q16881;Q16881-5;A0A182DWI3;Q16881-2;F8W809;Q16881-3;Q16881-6;Q16881-4;A0A087WSW9;E9PIR7;A0A087WSY9;E9PKD3;A0A0B4J225;E9PIZ5;E9PKI4;E9PLT3;E9PQI3 Q16881 TXNRD1 Thioredoxin reductase 1, cytoplasmic 0 ;;; 199.82 2.3291999999999998e-09 34850000.0 81868.3 76436.20000000001 99734.1 88747.5 98480.6 99013.5 85549.9 78304.40000000001 94786.0 84077.3 False True 80700.84302919269 76259.21667512607 91534.34728275925 95274.28720298137 92688.16472830901 94778.92341674182 89979.25522312436 81942.70828826659 84110.20253917052 98609.9492790396 0.8183843883828703 0.7733420129781531 0.9282465709797871 0.9661731691330739 0.9399473927932613 0.961149702537043 0.9124764375297192 0.8309780999520726 0.8529585823146638 1.0 16.589445594625175 -5.265694700179969 24.963070768366688 0.9209469555447357 0.7958631955717428 0.5205122852822246 0.04912059592958972 277.2331709766668 1626347.603369663 0.013885309097193554 0.03065581091712435 5.423820394991889e-06 5.265694700179969 -0.12508375997299293 VNASAS(ph)SLK ddPTM_PC-9_AZD4547_30min_R2 1 VNASASSLK 9 0 Q16658 Q16658 FSCN1 Fascin 1 VNAS(0.003)AS(0.946)S(0.051)LK 117.86 0.0018327000000000003 18467000.0 112490.0 107170.0 135900.0 174110.0 142750.0 144760.0 117400.0 137040.0 127150.0 118570.0 True False 148259.4800626464 141810.60667642538 134097.87720451743 133971.62947268505 122931.62654436122 135708.1343159082 127848.37256606418 115863.61686592012 133870.88941813022 114418.90038989934 1.29576039935212 1.23939844023308 1.1719906129805395 1.1708872311843312 1.0743996501054764 1.186063961928166 1.1173710997955926 1.0126265544512112 1.1700067817637239 1.0 16.803965859127864 -1.5228787452803376 0.20860113177795192 1.0305068840281164 2.3281186101920133 0.6702176845066117 0.05124579559425875 30.6651615462582 0.38020821639730473 0.0853089770826346 13.173293825906567 0.029999999999999995 1.5228787452803376 1.2976117261638969 VNASAS(ph)SLK ddPTM_PC-9_Lapatinib_30min_R1 4 VNASASSLK 9 0 Q16658 Q16658 FSCN1 Fascin 1 VNAS(0.088)AS(0.654)S(0.258)LK;VNAS(0.013)AS(0.693)S(0.294)LK;VNAS(0.001)AS(0.724)S(0.276)LK;VNAS(0.038)AS(0.883)S(0.079)LK 125.72 0.0014175000000000001 100762000.0 876120.0 861700.0 786930.0 871190.0 948000.0 888490.0 815507.0 774111.0 892730.0 711716.0 True False 863626.3681392687 859704.7865926883 722231.6530376456 935260.2188046451 892240.5038397111 850491.35387135 857729.9621536037 810079.0230911442 792181.3465363403 834735.1622980424 1.034611224189584 1.0299132292761024 0.8652225108731822 1.120427485323435 1.0688905225740764 1.01887567732253 1.0275474197016645 0.9704623210803539 0.9490211773940963 1.0 19.67095901855715 -7.765008791512794 23.50891754886205 0.969806271471331 1.0230689896787404 0.12255290309200628 0.061689237277740096 96.30937846325422 634269.4869024499 0.033036921535986224 0.016893303808308814 1.7178736115356818e-08 7.765008791512794 0.053262718207409354 VNASASS(ph)LK ddPTM_PC-9_AZD4547_30min_R2 1 VNASASSLK 9 0 Q16658 Q16658 FSCN1 Fascin 1 VNAS(0.001)AS(0.231)S(0.769)LK 92.943 0.0066384 29021000.0 215170.0 200540.0 190450.0 191410.0 213640.0 229120.0 205410.0 212430.0 187610.0 186030.0 True False 283589.58418596844 265360.63322655926 187924.50856218082 147283.38175502061 183979.77369483246 214793.0901800281 223691.09206810265 179603.82465577446 197526.68158659377 179517.14632312546 1.5797353623008006 1.4781910177477873 1.046833199007756 0.820441861803635 1.0248590592214206 1.1965045934576468 1.246070899909836 1.0004828415247475 1.1003220897409525 1.0 17.45376212201689 -5.216940521339087 4.4921915650024635 1.0560497187950268 1.5485515021794347 0.7469944105950341 0.11088825835913295 0.11028301709079423 5.059365316409222 0.03205407756143568 0.088795871608743 6.068194306575472e-06 5.216940521339087 0.49250178338440787 VNASASS(ph)LK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VNASASSLK 9 0 Q16658 Q16658 FSCN1 Fascin 1 VNASAS(0.088)S(0.912)LK;VNAS(0.089)AS(0.305)S(0.606)LK 125.72 0.0014175000000000001 34179000.0 348707.0 353194.0 274614.0 348393.0 351046.0 321496.0 373876.0 293703.0 279461.0 306587.0 True False 407736.2078228105 388256.766142172 281161.8392393952 328873.6697153459 282261.0563047962 304636.1837986378 338459.75865216594 285993.60745405225 283547.58843673056 362168.7961586437 1.125818160337056 1.0720326274936751 0.7763281713431647 0.908067379640533 0.7793632673455256 0.8411442041108247 0.9345359463378721 0.7896693765102176 0.7829155671172896 1.0 18.466302725952815 -5.173933960918861 5.295953243929282 0.8463020954622216 1.1098387700559271 0.6508612552176386 0.07261588303423752 0.12124529073205968 5.5229142375044065 0.017640190270673067 0.04919343069229156 6.69986480219773e-06 5.173933960918861 0.26353667459370556 VNASASS(ph)LK ddPTM_PC-9_Lapatinib_30min_R1 1 VNASASSLK 9 0 Q16658 Q16658 FSCN1 Fascin 1 VNAS(0.034)AS(0.04)S(0.926)LK 98.156 0.0045527 23709000.0 184310.0 148040.0 128960.0 137840.0 179090.0 179230.0 186100.0 164560.0 190160.0 110170.0 True False 181681.70560168577 147697.22247555057 118357.40659999587 147977.21342076056 168556.27830448718 171564.7507055363 195735.34740570685 172206.0583558158 168742.17832642636 129212.73770770253 1.4060665289259289 1.1430546639268844 0.9159886919797106 1.1452215628733595 1.3044865490412043 1.3277696436835817 1.5148301233930037 1.3327328358707966 1.3059252618588193 1.0 16.97938877141855 -6.281548277531226 4.6994140750087015 1.3283108633911724 1.1339084659120566 0.1424473334489087 0.16275170844701947 0.2996370447330789 17.978845128385693 0.051030167292759714 0.060881277352127894 5.229398313258172e-07 6.281548277531226 -0.1944023974791158 VNDAEPGS(ph)PEAPQGK ddPTM_PC-9_AZD4547_30min_R2 4 VNDAEPGSPEAPQGK 15 0 Q8N8A6 Q8N8A6 DDX51 ATP-dependent RNA helicase DDX51 1 VNDAEPGS(1)PEAPQGK;VNDAEPGS(1)PEAPQGK;VNDAEPGS(1)PEAPQGK;VNDAEPGS(1)PEAPQGK 212.92 1.4333e-17 175874000.0 346359.0 352278.0 417692.0 499554.0 439835.0 443341.0 393858.0 477323.0 390391.0 398764.0 True False 456493.95728525374 466144.9743282428 412153.13116489566 384389.54333236214 378771.5023547386 415618.81718533486 428910.59899595374 403563.69814135594 411026.27126097714 384803.3937343143 1.1863043952269243 1.2113847796521526 1.0710745743824308 0.9989245146776489 0.9843247448494687 1.080080955502947 1.1146227033852332 1.0487529598556362 1.0681461701056834 1.0 18.553761997302757 -5.322022456241426 4.600832213839082 1.0458731361567142 1.1995483159400935 0.7159337298272385 0.03878403634166786 0.11265251617343779 4.883569572633414 0.011247474584807054 0.02538133685582621 4.7640635243148736e-06 5.322022456241426 0.1536751797833793 VNDAEPGS(ph)PEAPQGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 VNDAEPGSPEAPQGK 15 0 Q8N8A6 Q8N8A6 DDX51 ATP-dependent RNA helicase DDX51 1 VNDAEPGS(1)PEAPQGK;VNDAEPGS(1)PEAPQGK;VNDAEPGS(1)PEAPQGK;VNDAEPGS(1)PEAPQGK;VNDAEPGS(1)PEAPQGK;VNDAEPGS(1)PEAPQGK 239.93 2.5646e-32 133814000.0 349410.0 392835.0 373002.0 418231.0 462966.0 379231.0 447848.0 366395.0 349802.0 304570.1 True False 408558.2118379273 431833.0626439302 381895.7822979633 394798.872993196 372251.1357292383 359343.4587619794 405424.59530126385 356777.51947759214 354917.1924896331 359786.2481544151 1.1355581652542204 1.2002489390828346 1.0614518599778695 1.0973150725420555 1.0346452585076944 0.9987692987302682 1.1268485034682632 0.9916374550382158 0.9864668099746484 1.0 18.4567805190068 -4.821477260935452 0.38456344348395244 1.0016848827493015 1.3003714903421566 0.5769056492031084 0.045627677096126196 4.20550198470982 0.5049837742085058 0.04000664676569922 0.5839476313192918 1.508421587362275e-05 4.821477260935452 0.29868660759285515 VNDAEPGS(ph)PEAPQGK ddPTM_PC-9_Lapatinib_30min_R1 4 VNDAEPGSPEAPQGK 15 0 Q8N8A6 Q8N8A6 DDX51 ATP-dependent RNA helicase DDX51 1 VNDAEPGS(1)PEAPQGK;VNDAEPGS(1)PEAPQGK;VNDAEPGS(1)PEAPQGK;VNDAEPGS(1)PEAPQGK 230.48 8.3447e-25 222050000.0 358353.0 377444.0 408705.0 345428.0 408605.0 367634.0 362331.0 358457.0 395631.0 291292.0 True False 353242.82050610863 376570.0516080909 375102.85254692426 370831.9274340288 384571.65724833857 351911.150816711 381090.72628080146 375112.2208316147 351070.87060087506 341641.434077808 1.033957785183803 1.102237650490391 1.0979430921762714 1.0854419003216476 1.125658713751779 1.0300599274986186 1.115469870653947 1.0979705135712075 1.027600389128795 1.0 18.382123429235925 -8.41038736576638 3.7335524956468267 1.001155719681067 1.087338768634947 0.4929021864220807 0.029850463861597377 0.17327905302655872 4.106865056475178 0.027368497473056377 0.0072345048981335746 3.886982937495871e-09 8.41038736576638 0.08618304895387996 VNEEKDGPIS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 VNEEKDGPISPK 12 1 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 VNEEKDGPIS(1)PK;VNEEKDGPIS(1)PK;VNEEKDGPIS(1)PK 157.37 0.00046664 35469600.0 83566.0 121211.0 91037.0 106906.0 102994.0 94717.0 90776.0 91598.0 92395.0 89745.0 True False 82374.33351587244 120930.34337668153 83552.28927298235 114768.22386796128 96936.09541399499 90666.17470611099 95475.93710962079 95853.97747493917 81988.50213751667 105257.30367230429 0.7825996927712209 1.1489021584019654 0.7937908948637352 1.090358767171798 0.920944124844623 0.8613765652631612 0.9070718494449026 0.910663432661734 0.7789340908139736 1.0 16.683560818001467 -6.519069916924542 24.76126518212298 0.8874551973261954 0.9625594000595802 0.05637755492733476 0.11746118501988997 364.92795448897044 2372425.1822819603 0.03535264720607687 0.03611192860079381 3.0264261655360245e-07 6.519069916924542 0.0751042027333848 VNEVNQFAAK ddPTM_PC-9_Lapatinib_30min_R1 1 VNEVNQFAAK 10 0 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 0 85.355 0.043006 0.0 19967.0 18629.0 16771.0 16663.0 17412.0 20797.0 15506.0 13743.0 16921.0 16408.0 False True 19682.266918500645 18585.86569506234 15392.153117932145 17888.45260613851 16387.86039330911 19907.56079017486 16308.824808559302 14381.549951288112 15015.178793970666 19244.10093771429 1.0227688465262434 0.9657954796234751 0.799837475793262 0.9295551225820583 0.8515783847918006 1.0344760118754277 0.8474713815597132 0.7473225170578571 0.7802483910559912 1.0 14.232128651217845 -7.505543187479009 24.561785564050094 0.8177506533421726 0.9266978321640202 0.17211881640178928 0.0914879302285539 857.2071690685776 1214534.8129736292 0.03838498595039339 0.02520146606060663 3.122171913126595e-08 7.505543187479009 0.10894717882184768 VNFPENGFLS(ph)PDKLSLLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VNFPENGFLSPDKLSLLEK 19 1 P31689 P31689 DNAJA1 DnaJ homolog subfamily A member 1 1 VNFPENGFLS(0.998)PDKLS(0.002)LLEK 55.049 0.015000999999999999 3163600.0 6697.0 6852.1 5418.4 6909.1 8582.7 5236.4 7133.4 5945.0 5394.8 6261.7 True False 7830.669828220725 7532.3312040486935 5547.595205396432 6522.005526604423 6900.981546427467 4961.7939658446385 6457.672710656355 5788.950049248175 5473.688744041115 7396.896642410073 1.058642591181228 1.0183096463538652 0.7499895528604956 0.8817218682238351 0.9329563302075523 0.6707940107471849 0.8730245970494326 0.7826187560952598 0.7399980030351845 1.0 12.852704401663814 -5.17629296149975 5.847040937415639 0.8229078446379677 1.045710419348581 0.4469599672684009 0.09324253037193263 0.19020062467397914 10.262241001043185 0.022860747316993286 0.0627541917250257 6.663571138621695e-06 5.17629296149975 0.22280257471061338 VNFPENGFLS(ph)PDKLSLLEK ddPTM_PC-9_Lapatinib_30min_R1 1 VNFPENGFLSPDKLSLLEK 19 1 P31689 P31689 DNAJA1 DnaJ homolog subfamily A member 1 1 VNFPENGFLS(0.995)PDKLS(0.005)LLEK 57.922 0.011965 3383400.0 25504.0 20179.0 21918.0 21650.0 21152.0 21551.0 19623.0 15813.0 19742.0 19474.0 True False 25140.308283139213 20132.276765294075 20115.986645926685 23242.213222282822 19907.880946432033 20629.313967834718 20638.982923923595 16547.729708194634 17518.448067523717 22840.05495252608 1.1007113746177186 0.881446073888166 0.880732847961116 1.017607587660916 0.8716214119366752 0.9032077204154513 0.9036310537265564 0.7245048115072279 0.7670055130750113 1.0 14.479278501337836 -6.988742078333959 1.2082502608348287 0.820449867327667 0.9550146805198851 0.21455580006583397 0.09458119789866909 0.6634878927373689 1.9878053350256562 0.05321622557438126 0.038786065976362215 1.0262612280798143e-07 6.988742078333959 0.13456481319221814 VNFTVDQIR ddPTM_PC-9_Lapatinib_30min_R1 1 VNFTVDQIR 9 0 P13639 P13639 EEF2 Elongation factor 2 0 133.99 0.005254399999999999 12353000.0 72330.0 67234.0 63797.0 66715.0 89321.0 67874.0 65019.0 58002.0 73151.0 70014.0 False True 71298.56093630259 67078.3238038448 58551.856923541614 71621.44365471584 84067.31439184268 64971.18724202183 68385.36567958958 60696.98466671131 64911.964065820524 82115.82661220929 0.8682681996615454 0.8168744877966234 0.7130398528416677 0.8722002397046673 1.0237650628404347 0.7912139464764478 0.8327915397178963 0.7391630477441562 0.790492731350879 1.0 16.325372686503172 -11.783899061285837 2.2951313684549794 1.6856596510432411 0.8274257496312496 0.2888363114275303 0.08118613834651947 10204417.52424102 1869342.9424034543 36225703.274930045 0.021777430581360384 1.6447539524726875e-12 11.783899061285837 -0.8582339014119915 VNGDAS(ph)PAAAESGAK ddPTM_PC-9_AZD4547_30min_R2 6 VNGDASPAAAESGAK 15 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 VNGDAS(0.999)PAAAES(0.001)GAK;VNGDAS(1)PAAAESGAK;VNGDAS(0.994)PAAAES(0.006)GAK;VNGDAS(1)PAAAESGAK;VNGDAS(1)PAAAESGAK;VNGDAS(0.93)PAAAES(0.07)GAK 194.27 1.3894e-09 420936900.0 201332.0 230798.0 242087.0 207885.0 237537.0 265563.0 261208.0 324008.0 255572.0 246470.0 True False 265351.38803425 305398.93999911926 238876.7682031641 159960.32504123307 204559.0877370775 248957.30362901054 284455.0059730532 273940.00856314215 269081.01415942085 237841.16031962933 1.11566638708645 1.2840457874856503 1.0043541995933043 0.6725510623403704 0.8600659678172407 1.0467376769203551 1.1959872950114294 1.151777128042095 1.1313475505997743 1.0 17.859638881069863 -7.005222464592052 24.229812356650374 1.1308455930946495 0.9838902428385305 0.13706765438945 0.15554549327363854 332.30394361936123 1541743.9026462827 0.06388260078061488 0.05471875801425622 9.88046844281015e-08 7.005222464592052 -0.14695535025611894 VNGDAS(ph)PAAAESGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 VNGDASPAAAESGAK 15 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 VNGDAS(1)PAAAESGAK;VNGDAS(1)PAAAESGAK;VNGDAS(0.996)PAAAES(0.004)GAK;VNGDAS(0.921)PAAAES(0.079)GAK;VNGDAS(0.831)PAAAES(0.169)GAK;VNGDAS(1)PAAAESGAK 180.39 8.8502e-06 433294000.0 236383.0 276126.0 256005.0 241582.0 287140.0 205773.0 253756.0 163982.0 179458.0 172791.0 True False 276397.9731229363 303537.9644268395 262109.13010436913 228046.94375941143 230876.97825173652 194981.90163733636 229718.3946456545 159677.6462532908 182082.23374881948 204116.6404871966 1.3541177851213637 1.4870809342263263 1.284114462587435 1.1172383751520538 1.1311031658206157 0.9552474564148373 1.1254270798174528 0.7822862745152163 0.8920499245637974 1.0 17.63903427645343 -5.94344470674322 0.6801695516863517 0.91251459990422 1.4917730628622676 0.7929939743029504 0.09365276939916226 0.42463867806056604 0.36906491842963246 0.053828408071361675 0.1539730173444802 1.139082797736992e-06 5.94344470674322 0.5792584629580476 VNGDAS(ph)PAAAESGAK ddPTM_PC-9_Lapatinib_30min_R1 6 VNGDASPAAAESGAK 15 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 VNGDAS(1)PAAAESGAK;VNGDAS(0.986)PAAAES(0.014)GAK;VNGDAS(0.999)PAAAES(0.001)GAK;VNGDAS(1)PAAAESGAK;VNGDAS(0.966)PAAAES(0.034)GAK;VNGDAS(1)PAAAESGAK 180.39 1.8581e-05 477823100.0 278472.0 294651.0 281742.0 234164.0 278925.0 273472.0 253489.0 249076.0 252711.0 194655.0 True False 274500.9382144889 293968.7537128042 258578.2603155712 251385.2017082046 262519.17988764885 261776.24005436816 266613.42008879693 260648.98025664207 224248.02601519538 228300.85738851657 1.202364902849884 1.287637537044093 1.1326206273309318 1.1011136996319015 1.1498825842817595 1.146628370338899 1.1678161139582626 1.141690763837458 0.9822478486516405 1.0 17.80057675208019 -1.5228787452806012 0.07217319998036298 0.8287311628339848 1.8774833431595075 0.5945058325415767 0.05398879056974014 178.01822767290426 0.949870387879983 2.337431533995795 18.87748946358373 0.029999999999981788 1.5228787452806012 1.0487521803255226 VNGDDHHEEDMDMS(ph)D ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VNGDDHHEEDMDMSD 15 0 Q5T757;Q05519-2;Q05519 Q5T757 SRSF11 Serine/arginine-rich splicing factor 11 1 VNGDDHHEEDMDMS(1)D;VNGDDHHEEDMDMS(1)D;VNGDDHHEEDMDMS(1)D 68.44 0.01661 16975100.0 22671.0 27118.0 31998.2 32237.4 35442.7 30076.9 31093.9 35675.8 33382.1 25627.7 True False 26508.752527339428 29810.09582338154 32761.158441849275 30431.242993060943 28497.957362550802 28499.614416643595 28148.46069165865 34739.34805163464 33870.2500597714 30273.799141238418 0.8756334942854822 0.9846830153132241 1.08216211282259 1.0052006638178443 0.9413406368192291 0.9413953724037872 0.9297961105025411 1.147505401933956 1.1187974757232886 1.0 14.885782113793072 -7.759597947995485 24.999943307497777 1.0998635879239864 0.9705929196131934 0.44588003093001183 0.06231755134151087 44.381248907581586 602564.659242859 0.0324984834449393 0.017512696652623453 1.7394103583269948e-08 7.759597947995485 -0.12927066831079304 VNGDDHHEEDMDMS(ph)D ddPTM_PC-9_Lapatinib_30min_R1 1 VNGDDHHEEDMDMSD 15 0 Q5T757;Q05519-2;Q05519 Q5T757 SRSF11 Serine/arginine-rich splicing factor 11 1 VNGDDHHEEDMDMS(1)D 98.281 0.0012959000000000002 11843000.0 47725.0 36147.0 40917.0 36923.0 40378.0 42059.0 33334.0 29777.0 42514.0 34806.0 True False 47044.4327483069 36063.30384236506 37552.962204187534 39638.440591517276 38003.04542620238 40260.234614317655 35059.871415485344 31160.5481262829 37725.62562773291 40822.17072392026 1.1524235951700783 0.883424453007672 0.9199158579331232 0.9710027636597639 0.9309413182169174 0.9862345362914929 0.8588438780630933 0.7633241342558982 0.924145506197374 1.0 15.317065279445053 -7.266256341790844 23.754185167962646 0.8668553800649315 0.9653232725913234 0.17457115418775726 0.08787490633127334 317.2270619946345 1564347.3624535115 0.034693014126103386 0.024278651126923668 5.4168106943014155e-08 7.266256341790844 0.09846789252639199 VNGTTVS(ph)SPSTSLQR ddPTM_PC-9_Lapatinib_30min_R1 2 VNGTTVSSPSTSLQR 15 0 A0A075B6G3;P11532-11;A0A087WTU7;A0A5H1ZRP8;A0A087WV90;P11532;P11532-4;P11532-16;P11532-12;P11532-7;P11532-5;A0A5H1ZRP7;P11532-6;A0A5H1ZRR9;A0A5H1ZRQ1;A0A5H1ZRP9;H0Y304;P11532-17;P11532-13;A0A5H1ZRQ8;P11532-2;P11532-3;P11532-9;P11532-14;P11532-8;P11532-15 A0A075B6G3 DMD Dystrophin 1 VNGT(0.001)T(0.113)VS(0.405)S(0.405)PS(0.069)T(0.006)SLQR;VNGTT(0.001)VS(0.453)S(0.453)PS(0.081)T(0.011)SLQR 160.63 1.5626e-14 0.0 29408.0 20575.0 23272.0 20085.2 24059.0 21775.6 20436.3 19937.8 26325.0 18155.1 True False 28988.636527233306 20527.35985162422 21358.665992517857 21562.332610263038 22643.896921813925 20844.308349402876 21494.391618416124 20864.182974517378 23360.00128546054 21293.184844849857 1.3614044464675155 0.9640342673580432 1.0030752162321006 1.0126400896518906 1.063434008900306 0.9789192411225628 1.009449350814936 0.9798526207583155 1.097064692561037 1.0 14.378104130947554 -4.75667981451402 24.999999043699887 1.0116493335191317 1.3614049758588724 0.8830868097573201 0.03813396396122432 43.83477861950795 230218.55273761504 0.009114474866905697 0.07234470632508937 1.7511372463436262e-05 4.75667981451402 0.34975564233974077 VNHEPEPAGGATPGATLPKS(ph)PSQLR ddPTM_PC-9_AZD4547_30min_R2 5 VNHEPEPAGGATPGATLPKSPSQLR 25 1 O00499-6;O00499-11;O00499-2;O00499 O00499-6 BIN1 Myc box-dependent-interacting protein 1 1 VNHEPEPAGGATPGATLPKS(0.744)PS(0.256)QLR;VNHEPEPAGGATPGAT(0.001)LPKS(0.772)PS(0.228)QLR;VNHEPEPAGGAT(0.001)PGAT(0.014)LPKS(0.727)PS(0.257)QLR;VNHEPEPAGGATPGATLPKS(0.744)PS(0.256)QLR;VNHEPEPAGGATPGATLPKS(0.737)PS(0.263)QLR 156.9 5.6543e-08 399993800.0 196292.0 155325.0 323395.0 573216.0 435960.0 345921.0 296888.0 365528.0 277265.0 418077.0 True False 258708.77287276156 205530.76870407545 319106.5709974609 441069.90729891777 375434.4792173712 324290.505185778 323310.4568517347 309044.04659782595 291920.66185228404 403440.2514827342 0.6412567212169541 0.5094453712754327 0.7909636428806299 1.0932719421968582 0.9305826025974466 0.8038129660933361 0.8013837381458484 0.7660218470071322 0.7235784252548166 1.0 18.621995504142674 -5.392309581438048 5.0265966006204446 0.8659781090099729 0.5789127518120409 0.530108408649294 0.11040603339603328 0.17979103624705345 6.506257637224652 0.03144754654714968 0.06758080523878415 4.0521957671800524e-06 5.392309581438048 -0.2870653571979319 VNHEPEPAGGATPGATLPKS(ph)PSQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 10 VNHEPEPAGGATPGATLPKSPSQLR 25 1 O00499-6;O00499-11;O00499-2;O00499 O00499-6 BIN1 Myc box-dependent-interacting protein 1 1 VNHEPEPAGGATPGAT(0.018)LPKS(0.738)PS(0.244)QLR;VNHEPEPAGGAT(0.017)PGAT(0.343)LPKS(0.456)PS(0.184)QLR;VNHEPEPAGGATPGAT(0.139)LPKS(0.642)PS(0.219)QLR;VNHEPEPAGGATPGAT(0.001)LPKS(0.762)PS(0.237)QLR;VNHEPEPAGGATPGAT(0.001)LPKS(0.75)PS(0.25)QLR;VNHEPEPAGGATPGAT(0.037)LPKS(0.726)PS(0.237)QLR;VNHEPEPAGGATPGAT(0.019)LPKS(0.763)PS(0.218)QLR;VNHEPEPAGGATPGAT(0.008)LPKS(0.751)PS(0.242)QLR;VNHEPEPAGGATPGAT(0.087)LPKS(0.673)PS(0.241)QLR;VNHEPEPAGGATPGAT(0.002)LPKS(0.871)PS(0.127)QLR 168.45 8.6649e-11 708420000.0 385551.0 242994.7 390024.2 603606.0 593686.0 592282.0 549348.8 767568.0 635999.0 425591.0 True False 450817.16932064015 267117.60791997385 399323.85610301484 569787.9127370554 477357.4901106097 561221.6892671289 497310.50472310744 747420.1533055227 645299.2821831015 502747.27932349744 0.8967073276403702 0.5313158696341637 0.7942834750699191 1.1333485752598575 0.9494979082789815 1.1163097491493446 0.9891858696725206 1.4866717017569144 1.2835460453439425 1.0 18.93947384367332 -6.074427002995288 0.7277733688335044 1.2309670603703338 0.6641567862762285 0.504061184974913 0.1754374988880475 0.6559936994125823 0.7037503865230326 0.10029639754449897 0.23040502486646636 8.425059894738023e-07 6.074427002995288 -0.5668102740941052 VNHEPEPAGGATPGATLPKS(ph)PSQLR ddPTM_PC-9_Lapatinib_30min_R1 5 VNHEPEPAGGATPGATLPKSPSQLR 25 1 O00499-6;O00499-11;O00499-2;O00499 O00499-6 BIN1 Myc box-dependent-interacting protein 1 1 VNHEPEPAGGATPGATLPKS(0.731)PS(0.269)QLR;VNHEPEPAGGATPGATLPKS(0.762)PS(0.238)QLR;VNHEPEPAGGATPGATLPKS(0.788)PS(0.211)QLR;VNHEPEPAGGATPGAT(0.007)LPKS(0.734)PS(0.259)QLR;VNHEPEPAGGATPGATLPKS(0.753)PS(0.247)QLR 196.0 1.7326e-25 530423000.0 627225.0 339395.0 542569.0 423907.0 382828.0 395142.0 316380.0 290514.0 427182.0 318471.0 True False 618280.6564810213 338609.151729867 497961.0711969066 455082.5348922969 360310.8097088067 378242.69778099086 332760.60834077065 304012.3410134991 379068.2647341162 373518.288014066 1.6552888474840568 0.9065396865309995 1.3331638293923491 1.2183674789041636 0.9646403436482822 1.0126484028186244 0.8908817024997703 0.8139155451527733 1.014858647884575 1.0 18.51081935568771 -6.255733853293899 3.0387880637999123 0.9347862535510345 1.263682206412669 0.4490711370710744 0.17865268831880252 0.25173425472581984 4.745912604389707 0.05462353349871279 0.06845121508406499 5.549657058709026e-07 6.255733853293899 0.3288959528616344 VNIGQGSHPQK ddPTM_PC-9_Lapatinib_30min_R1 2 VNIGQGSHPQK 11 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 97.45200000000001 0.0045193 17775700.0 136890.0 153311.0 152422.0 145347.0 157073.0 142560.0 148115.0 135134.0 151594.0 130128.0 False True 134937.92349744865 152956.0177989 139890.45152593503 156036.30324337838 147834.27495739973 136463.04112359145 155783.66996773894 141412.81897092127 134519.88736441033 152620.45141533934 0.8841405083400672 1.0021986986701241 0.9165904715170771 1.0223813505749841 0.9686400058867958 0.8941333868304627 1.0207260463657735 0.9265653302654848 0.881401451227068 1.0 17.219588773296863 VNIS(ph)PTISSESK ddPTM_PC-9_Lapatinib_30min_R1 2 VNISPTISSESK 12 0 Q8TAT5 Q8TAT5 NEIL3 Endonuclease 8-like 3 1 VNIS(0.634)PT(0.272)IS(0.074)S(0.02)ESK;VNIS(0.847)PT(0.13)IS(0.02)S(0.003)ES(0.001)K 135.91 6.1818e-05 7666900.0 57638.0 52724.0 58125.0 49224.0 52073.0 43924.0 46021.0 49431.0 50883.0 32785.0 True False 56816.07155048535 52601.92081735291 53346.1868689885 52844.09716645033 49010.168519457024 42045.47291184501 48403.74219751757 51727.74471673743 45152.02071825598 38451.84356673346 1.4775903124613683 1.3679947679507716 1.387350564255932 1.3742929405904558 1.2745856628278305 1.0934579206553459 1.2588146030895113 1.345260458759631 1.1742485282895294 1.0 15.230765149149383 -1.5228787454093544 0.06196012561039596 0.6375957034179359 2.6523393546243264 0.7113357884024283 0.07523830302939989 199.03132867106967 0.9228708801664961 5.913805012647868 35.921818050191554 0.029999999991087833 1.5228787454093544 2.0147436512063903 VNISPTIS(ph)SESK ddPTM_PC-9_Lapatinib_30min_R1 1 VNISPTISSESK 12 0 Q8TAT5 Q8TAT5 NEIL3 Endonuclease 8-like 3 1 VNIS(0.006)PT(0.014)IS(0.721)S(0.233)ES(0.025)K 69.846 0.031176 3427000.0 25914.0 22402.0 22606.0 23592.0 21250.0 20347.0 19644.0 17122.0 18739.0 21301.0 True False 25544.461607954403 22350.129545374784 20747.421941683508 25327.034380604906 20000.116779107448 19476.806241173635 20661.07020116979 17917.550626934084 16628.41648958196 24982.8494682016 1.0224799072847006 0.8946189094171277 0.830466595417429 1.0137768477067193 0.8005538681471775 0.7796070766853034 0.8270101546049577 0.7171940354417821 0.6655932707254535 1.0 14.608650415310192 -6.3873404134535985 6.7502989229227195 0.7830138856997646 0.9288227920762521 0.3318382730923535 0.09697729422691125 0.2851870500544642 14.459995574717183 0.02950371293322356 0.033445011519998014 4.09882698297375e-07 6.3873404134535985 0.14580890637648747 VNIVPVIAK ddPTM_PC-9_Lapatinib_30min_R1 2 VNIVPVIAK 9 0 Q15019-2;Q15019-3;Q15019;B5MCX3;H7C2Y0;C9J2Q4;H7C310 Q15019-2 SEPT2 Septin-2 0 ; 132.57 7.1299e-06 0.0 53125.0 52368.0 58375.0 56246.0 54461.0 50420.0 45736.0 45121.0 48642.0 47699.0 False True 52367.427758068174 52246.745113480305 53575.63283401636 60382.518471155636 51257.71105444562 48263.65413476058 48103.986292033325 47217.48638230887 43163.425737032136 55943.70859507766 0.9360735831280919 0.9339163674622272 0.9576703829522367 1.0793442191722795 0.9162372738899125 0.862718174157785 0.8598640937484411 0.8440178094747085 0.7715510255040541 1.0 15.771688275022136 -6.564931647238171 4.523071104016783 0.8586844246870651 0.9752168786430653 0.3783441106456913 0.06512948729622316 0.20355073519709294 9.331250275498927 0.021639463481045278 0.02208315618310778 2.7231298624525385e-07 6.564931647238171 0.1165324539560002 VNKDDIQK ddPTM_PC-9_AZD4547_30min_R2 1 VNKDDIQK 8 1 P35579;Q5BKV1;B1AH99 P35579 MYH9 Myosin-9 0 76.221 0.032747000000000005 8380600.0 62219.0 60739.0 84374.0 93516.0 89113.0 65498.0 69569.0 77969.0 68106.0 82788.0 False True 82003.34776440395 80371.69393411773 83255.14563100785 71957.33100779745 76741.19815234766 61402.39970588112 75760.50622698914 65920.6825993791 71705.94411884532 79889.61731870606 1.0264581370726251 1.006034283697824 1.0421272303618077 0.9007094216102687 0.9605903836815449 0.7685904848051365 0.948314796962357 0.8251470567996305 0.8975627437641444 1.0 16.285720398145365 -5.782810343021685 9.245550817067665 0.8917635988524032 1.0230136904617788 0.4455839015842612 0.06327529158203037 0.19965579063653807 79.22862378860098 0.01690527359698964 0.025676103296990892 1.6488823034174732e-06 5.782810343021685 0.13125009160937562 VNLEESSGVENS(ph)PAGARPK ddPTM_PC-9_AZD4547_30min_R2 5 VNLEESSGVENSPAGARPK 19 1 Q8WVM8-2;Q8WVM8-3;Q8WVM8 Q8WVM8-2 SCFD1 Sec1 family domain-containing protein 1 1 VNLEESSGVENS(1)PAGARPK;VNLEES(0.002)S(0.004)GVENS(0.993)PAGARPK;VNLEES(0.001)S(0.002)GVENS(0.997)PAGARPK;VNLEESS(0.004)GVENS(0.996)PAGARPK;VNLEESSGVENS(1)PAGARPK 166.34 4.0988e-07 140927800.0 171979.0 226227.0 188380.0 256416.0 204620.0 198894.0 192688.0 216704.0 199242.0 225512.0 True False 226664.74461457744 299350.4536398962 185881.9581146944 197303.2527877089 176212.04499829837 186457.1267382441 209836.85871388257 183217.3761625238 209773.52535939513 217616.89352051078 1.0415769701868935 1.375584628551284 0.8541706257615275 0.9066541186018386 0.8097351365862139 0.8568136587276032 0.964248939129834 0.8419262548900196 0.9639579077054677 1.0 17.731431031265124 -5.276530212177174 24.955354569295846 0.8918534891907784 1.2085808034225531 0.62831325192348 0.0948785557690998 377.6949163296191 624585.1472923475 0.022866878396369264 0.04789248156721768 5.290171942617915e-06 5.276530212177174 0.3167273142317747 VNLEESSGVENS(ph)PAGARPK ddPTM_PC-9_Lapatinib_30min_R1 3 VNLEESSGVENSPAGARPK 19 1 Q8WVM8-2;Q8WVM8-3;Q8WVM8 Q8WVM8-2 SCFD1 Sec1 family domain-containing protein 1 1 VNLEES(0.002)S(0.002)GVENS(0.997)PAGARPK;VNLEESSGVENS(1)PAGARPK;VNLEESSGVENS(1)PAGARPK 256.66 7.7685e-65 125442100.0 109993.0 115627.0 111171.0 100270.0 90405.0 101612.0 107282.0 103712.0 94953.0 89538.0 True False 108424.47964975421 115359.27278560198 102030.94951246992 107644.19029091432 85087.55564306861 97266.29162914101 112836.53702514262 108530.8381392703 84258.39324058258 105014.52399811464 1.032471276560762 1.0985077910525316 0.9715889348248792 1.0250409771209066 0.8102455965481138 0.9262175166445287 1.0744850591063804 1.0334840744621077 0.8023499039246732 1.0 16.680229347575732 -5.5168378538465666 2.070474691329833 0.9509623248235068 1.0647119532728493 0.20077001424294072 0.08680878948148256 0.5635044638187239 4.728399313889665 0.026165439727777073 0.06720664544487205 3.042020568232532e-06 5.5168378538465666 0.11374962844934244 VNLFPGLS(ph)PSALK ddPTM_PC-9_AZD4547_30min_R2 1 VNLFPGLSPSALK 13 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 VNLFPGLS(0.567)PS(0.433)ALK 171.15 0.00022725 2012900.0 34285.0 34232.0 43658.0 57172.0 47333.0 49511.0 36158.0 50251.0 40810.0 47400.0 True False 45186.916827698755 45296.82455675465 43079.06639436956 43991.878698594825 40761.62997705245 46415.069343153715 39375.991952672535 42485.862603103815 42967.13328473373 45740.54042743713 0.9878964350975117 0.990299286660454 0.9418136732055071 0.9617699810168097 0.8911488494919898 1.0147468505927835 0.8608554158895143 0.9288447885853788 0.9393665418732178 1.0 15.481185790934749 -5.312080455403302 1.8700843910361797 0.9364655274283321 0.9938909191991421 0.1443191799132637 0.04328970693644577 0.6739616088771826 4.242586210221827 0.011891098477494212 0.045668558675131206 4.874381811773145e-06 5.312080455403302 0.057425391770809964 VNLFPGLS(ph)PSALK ddPTM_PC-9_Lapatinib_30min_R1 1 VNLFPGLSPSALK 13 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 VNLFPGLS(0.542)PS(0.458)ALK 160.63 8.198899999999999e-05 11101000.0 156620.0 136340.0 157840.0 132860.0 126680.0 116760.0 102810.0 92992.0 116070.0 94217.0 True False 154386.57007940966 136024.31310670447 144863.0044800194 142630.9676079678 119228.93146246269 111766.4469808538 108132.9987468066 97312.74780398625 102996.97432871436 110502.28291373889 1.3971346655338157 1.2309638273526782 1.3109503320678308 1.2907513206700845 1.0789725634495357 1.0114401624453473 0.9785589572951916 0.8806401572712416 0.9320800585551398 1.0 16.75371664961287 -6.476218159965386 1.4443037842148738 0.9391988411260997 1.3164209796074307 0.9160795187903573 0.049708053501256365 0.10493401871876287 0.4468320712065101 0.0199924946409444 0.02305370705289525 3.340272053598536e-07 6.476218159965386 0.3772221384813309 VNLFPGLSPS(ph)ALK ddPTM_PC-9_AZD4547_30min_R2 1 VNLFPGLSPSALK 13 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 VNLFPGLS(0.307)PS(0.693)ALK 176.56 7.8822e-05 4441700.0 98424.0 91489.0 123830.0 155670.0 143170.0 129440.0 110460.0 141690.0 109970.0 125130.0 True False 129720.78465362171 121061.0300850937 122187.93329091533 119782.68657752487 123293.31679408847 121346.09633773932 120290.72601062548 119795.06621228984 115782.78969179526 120749.23678660751 1.0742990026750152 1.00258215543869 1.0119147461515665 0.9919953928090597 1.021069118738837 1.0049429674838162 0.9962027853079327 0.992097916312267 0.9588697433873712 1.0 16.881654544759506 VNLFPGLSPS(ph)ALK ddPTM_PC-9_Lapatinib_30min_R1 1 VNLFPGLSPSALK 13 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 VNLFPGLS(0.313)PS(0.687)ALK 134.37 4.6298e-05 16063000.0 198000.0 184060.0 213340.0 169480.0 164440.0 156470.0 135270.0 130250.0 160010.0 126020.0 True False 195176.48369124686 183633.8203786125 195800.00871621526 181944.12456870623 154767.96250147873 149778.14284938484 142273.61871880677 136301.89050100272 141987.98882000137 147802.38908890533 1.3205231992146305 1.2424279574273596 1.3247418389051793 1.2309958295685204 1.047127610423019 1.0133675360233254 0.9625934979523713 0.9221900359067614 0.9606609858964694 1.0 17.17331006394022 -6.331294504399749 1.7310790626983785 0.9616213456464848 1.2958146632217193 0.958236033195643 0.03077247075417121 0.06583497550994234 0.3906512194105715 0.011304572311491727 0.014270883250762516 4.6634303585510404e-07 6.331294504399749 0.3341933175752345 VNLS(ph)PNR ddPTM_PC-9_AZD4547_30min_R2 1 VNLSPNR 7 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 VNLS(1)PNR 96.665 0.012731999999999999 32395000.0 89867.0 103140.0 151250.0 168240.0 180430.0 139240.0 134100.0 141020.0 129140.0 148690.0 True False 118442.83665027842 136477.9879873709 149244.32617500555 129454.86728208893 155380.40894850495 130533.3007885259 146034.64021387725 119228.59931722157 135966.07675546478 143484.40835771343 0.8254753112616586 0.9511694653758115 1.0401431617777757 0.9022225394647188 1.0829079669836617 0.9097385721736413 1.0177735817107456 0.8309516043023923 0.9476017520767476 1.0 17.130534450312624 -4.769221427238369 5.157666329606593 0.9640821178431612 0.8181998581434505 0.2647114397680256 0.0699087667544879 0.2154217438752157 15.92207463995586 0.016878211966273645 0.11208596568595011 1.7012908754718123e-05 4.769221427238369 -0.1458822596997107 VNLS(ph)PNR ddPTM_PC-9_Lapatinib_30min_R1 3 VNLSPNR 7 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 VNLS(1)PNR;VNLS(1)PNR;VNLS(1)PNR 106.68 0.010019 93737000.0 278028.0 407957.0 442414.0 409546.0 424912.0 379527.0 346761.0 353370.0 367559.0 301010.0 True False 274063.2697359094 407012.40063130425 406040.42868742556 439665.3790454066 399919.51156913413 363295.5149306485 364714.58786539634 369788.86024060764 326160.63485213974 353039.17742938676 0.7762970436637341 1.1528816818431233 1.1501285258026068 1.2453727720724321 1.1327907414726632 1.0290515561925508 1.0330711467237792 1.0474442608131531 0.9238652696480885 1.0 18.429468765431423 -6.8823676457537335 4.857700672914627 1.008423276286916 1.1064095679187484 0.1076339899511457 0.11937123630818977 0.47689657131430696 18.249263560581557 0.04403492169898405 0.0387967522532118 1.3110895450917025e-07 6.8823676457537335 0.09798629163183237 VNNGNTAPEDS(ph)SPAK ddPTM_PC-9_AZD4547_30min_R2 2 VNNGNTAPEDSSPAK 15 0 E9PJ27;G3V167;Q9UGN5-2;Q9UGN5 E9PJ27 PARP2 Poly [ADP-ribose] polymerase 2 1 VNNGNTAPEDS(0.899)S(0.101)PAK;VNNGNTAPEDS(0.5)S(0.5)PAK 278.89 3.2485999999999993e-75 9643800.0 45090.0 41862.0 44884.0 53587.0 47174.0 47063.0 46432.0 45247.0 43669.0 50901.0 True False 59427.68206973715 55393.07284397238 44288.8088333154 41233.345060896936 40624.70438251268 44120.14317014084 50564.35804929725 38255.11582262319 45977.254187969564 49118.97148305859 1.2098722810235165 1.1277327511443875 0.9016640107904308 0.8394586412526686 0.8270674885064394 0.8982301916756975 1.0294262384288153 0.7788256689335932 0.9360386180689345 1.0 15.58399273154773 -5.186690424912083 3.256873427043053 0.8916251887522807 1.1952368836958354 0.6878139065144971 0.07275196741807409 0.1335577247806071 2.720877988068431 0.0190005468545594 0.061312062801091305 6.505932829381362e-06 5.186690424912083 0.30361169494355467 VNNGNTAPEDS(ph)SPAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VNNGNTAPEDSSPAK 15 0 E9PJ27;G3V167;Q9UGN5-2;Q9UGN5 E9PJ27 PARP2 Poly [ADP-ribose] polymerase 2 1 VNNGNT(0.001)APEDS(0.798)S(0.201)PAK 128.74 1.7117e-05 5541800.0 16814.0 19308.0 17938.0 14941.0 16082.0 16633.0 16731.0 17362.0 16540.0 16655.0 True False 19660.27810836245 21224.770637873382 18365.70995024384 14103.904209375558 12930.847545602963 15760.736199276957 15146.118558049671 16906.26589655959 16781.86620939424 19674.41965909255 0.9992812214553143 1.078800341033914 0.9334816613894942 0.7168650691486814 0.6572416248947379 0.8010775653040988 0.7698381360412774 0.8593018848587153 0.8529789696560878 1.0 14.264033460400512 -5.549416914156044 4.762557648668823 0.7947493653895841 1.0338852993300383 0.5222012645060274 0.08880286617931457 0.13409057419304585 7.611966181977742 0.024544669279592153 0.045844772074006834 2.822169446966169e-06 5.549416914156044 0.23913593394045418 VNNGNTAPEDS(ph)SPAK ddPTM_PC-9_Lapatinib_30min_R1 1 VNNGNTAPEDSSPAK 15 0 E9PJ27;G3V167;Q9UGN5-2;Q9UGN5 E9PJ27 PARP2 Poly [ADP-ribose] polymerase 2 1 VNNGNTAPEDS(0.5)S(0.5)PAK 166.79 0.00024565 4845500.0 26917.0 26740.0 23848.0 24400.0 21863.0 22849.0 20092.0 19138.0 23287.0 16352.0 True False 26533.158644026746 26678.0851729007 21887.309495942147 26194.45739601388 20577.061324311817 21871.801533620495 21132.265449088958 20027.221346703926 20664.17283701878 19178.421412329597 1.3834902296478306 1.3910469792758675 1.141246665998852 1.365829691236931 1.0729277911832227 1.1404380508376646 1.1018772084913755 1.0442580708873486 1.0774699540043484 1.0 14.227196355675614 -4.219278961042589 0.2786674898091217 0.9963531915246804 1.8937618761492847 0.7397056830798884 0.07247431319574242 5.691487963040118 0.2866534172227891 0.08385227168483815 1.8423789777909598 6.0356081868913575e-05 4.219278961042589 0.8974086846246043 VNNGNTAPEDS(ph)SPAKK ddPTM_PC-9_AZD4547_30min_R2 2 VNNGNTAPEDSSPAKK 16 1 E9PJ27;G3V167;Q9UGN5-2;Q9UGN5 E9PJ27 PARP2 Poly [ADP-ribose] polymerase 2 1 VNNGNTAPEDS(0.5)S(0.5)PAKK;VNNGNTAPEDS(0.5)S(0.5)PAKK 110.61 0.00025269999999999996 29146300.0 167631.0 151646.0 169917.0 180398.0 212334.0 201612.0 186911.0 182417.0 194356.0 184108.0 True False 220934.1710585962 200662.603900842 167663.78955820468 138810.02822131666 182855.08925163143 189005.16976857447 203545.7169054148 154228.6441756457 204629.2613743619 177662.43495811356 1.2435615391103052 1.1294599443498061 0.9437211056897525 0.781313327457451 1.029227643394295 1.0638443057089424 1.1456879838070642 0.8680993492631534 1.151786878428218 1.0 17.43877914382402 -5.020207083042027 3.597333128506318 0.9949375849604766 1.2321749391369985 0.3461701254226913 0.10876823761083211 0.2555046063870157 6.89047985039794 0.02903564489726089 0.11817317010584621 9.545373289635857e-06 5.020207083042027 0.23723735417652192 VNNGNTAPEDS(ph)SPAKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VNNGNTAPEDSSPAKK 16 1 E9PJ27;G3V167;Q9UGN5-2;Q9UGN5 E9PJ27 PARP2 Poly [ADP-ribose] polymerase 2 1 VNNGNTAPEDS(0.596)S(0.404)PAKK 66.777 0.011978 7742100.0 63706.0 52632.0 47511.0 60465.0 63037.0 68646.0 68751.0 61066.0 57516.0 49726.0 True False 74490.16754914593 57856.95712722973 48643.84242647085 57077.34208017488 50685.3523648908 65046.08291562347 62238.40756586416 59463.08220477528 58357.062690418345 58740.93016920061 1.2681135170073123 0.9849513271338293 0.8281081400371845 0.9716792348327845 0.8628626107706147 1.1073383197756854 1.059540722058524 1.012293847467082 0.9934650766054172 1.0 15.842078490630461 -6.788171492391784 24.99877121672787 1.0368592187662498 0.973993339919033 0.045342841837899606 0.1138382866624017 717.1818984372736 670673.8992546761 0.0415760035586075 0.036676384410922774 1.628652790033688e-07 6.788171492391784 -0.06286587884721673 VNNGNTAPEDS(ph)SPAKK ddPTM_PC-9_Lapatinib_30min_R1 1 VNNGNTAPEDSSPAKK 16 1 E9PJ27;G3V167;Q9UGN5-2;Q9UGN5 E9PJ27 PARP2 Poly [ADP-ribose] polymerase 2 1 VNNGNTAPEDS(0.5)S(0.5)PAKK 81.357 0.0033399000000000002 21527000.0 90790.0 54899.0 53875.0 63744.0 64951.0 56986.0 47093.0 56587.0 56554.0 56226.0 True False 89495.31795115305 54771.884738484536 49445.605463514075 68431.94640375051 61130.70987857917 54548.841620854204 49531.24511218132 59216.2386009998 50184.29297997856 65944.58918356433 1.3571290542432914 0.8305743566924151 0.7498053453009854 1.0377188978046756 0.9270011480155684 0.8271920758958896 0.7511040060361195 0.8979696338112686 0.7610069848230433 1.0 16.00896666937833 -4.759338768952864 24.999924010253608 0.86055961491715 1.3571296887396171 0.7014583378056779 0.09633967048505107 30.734452147287 365689.2172751783 0.024037582048297874 0.15367682853959155 1.7404487165773357e-05 4.759338768952864 0.4965700738224671 VNNGNTAPEDSS(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VNNGNTAPEDSSPAK 15 0 E9PJ27;G3V167;Q9UGN5-2;Q9UGN5 E9PJ27 PARP2 Poly [ADP-ribose] polymerase 2 1 VNNGNTAPEDS(0.025)S(0.975)PAK 151.07 0.00014279 3514800.0 18734.0 20562.0 16932.0 20041.0 22745.0 16434.0 22196.0 18074.0 16931.0 16506.0 True False 21905.29618663388 22603.2594704761 17335.723094967587 18918.167743798647 18288.280526348666 15572.17210959643 20093.434194876005 17599.576650985953 17178.583844694916 19498.407138575883 1.1234402908377157 1.159236203749051 0.889084065778398 0.9702417027886712 0.9379371553980382 0.7986381656165266 1.030516700778235 0.9026161227378794 0.881024984379806 1.0 14.251068651876164 -5.258724751856779 24.998577006821563 0.9239330883318312 1.1413382685382725 0.652839571303947 0.0627186684451452 129.6673187327545 1194069.6875500083 0.015623111519924522 0.03764828339640493 5.511568992059497e-06 5.258724751856779 0.21740518020644128 VNNGNTAPEDSS(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 1 VNNGNTAPEDSSPAK 15 0 E9PJ27;G3V167;Q9UGN5-2;Q9UGN5 E9PJ27 PARP2 Poly [ADP-ribose] polymerase 2 1 VNNGNTAPEDS(0.027)S(0.973)PAK 184.0 5.0847e-07 5969400.0 20925.0 22608.0 16418.0 20433.0 18488.0 16439.0 15554.0 15760.0 17325.0 16452.0 True False 20626.605662824968 22555.652565031392 15068.175415312739 21935.710982489836 17400.572188806516 15735.942291180674 16359.310013693495 16492.267134708633 15373.67605966205 19295.706279087975 1.0689738620855447 1.1689467200004198 0.7809082081459289 1.1368182467756056 0.9017846736019536 0.8155152272521244 0.847821260184871 0.8547117631336659 0.7967407793890142 1.0 14.235992231238376 -6.461753368271935 6.915277186578752 0.8534006304957807 1.0293613340102956 0.36522735543548845 0.10978424167039665 0.27266041253834905 26.088240659660592 0.03337167206891219 0.03759164945625007 3.4533979886544586e-07 6.461753368271935 0.17596070351451487 VNNGNTAPEDSS(ph)PAKK ddPTM_PC-9_AZD4547_30min_R2 2 VNNGNTAPEDSSPAKK 16 1 E9PJ27;G3V167;Q9UGN5-2;Q9UGN5 E9PJ27 PARP2 Poly [ADP-ribose] polymerase 2 1 VNNGNTAPEDS(0.347)S(0.653)PAKK;VNNGNTAPEDS(0.374)S(0.626)PAKK 107.09 0.00043391 29614200.0 114896.0 91037.0 103026.0 119129.0 124623.0 112819.0 119392.0 118484.0 117112.0 119713.0 True False 151430.5380147377 120462.92992443545 101659.80792400749 91665.64957470266 107321.24759956493 105764.41009523669 130017.65670704866 100175.02029145964 123302.30123111332 115521.88430780142 1.3108385387071748 1.0427715116165255 0.880004758692654 0.793491641206828 0.9290122667460448 0.9155357076191165 1.1254807475319923 0.8671518898059961 1.0673501559460494 1.0 16.81780665414425 -4.811805534041458 3.050576948884148 0.9421029698890653 1.3559413703375902 0.5823247716935148 0.09256243345962532 0.24083626699464145 3.4365591060585134 0.024152044998696835 0.23611182783450077 1.5423909415514568e-05 4.811805534041458 0.41383840044852493 VNNGNTAPEDSS(ph)PAKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VNNGNTAPEDSSPAKK 16 1 E9PJ27;G3V167;Q9UGN5-2;Q9UGN5 E9PJ27 PARP2 Poly [ADP-ribose] polymerase 2 1 VNNGNTAPEDS(0.295)S(0.705)PAKK;VNNGNTAPEDS(0.285)S(0.715)PAKK;VNNGNTAPEDS(0.116)S(0.884)PAKK 109.77 0.00029605 37044200.0 180532.0 186626.0 146037.0 210535.0 203696.0 200847.0 208864.0 203741.0 173924.0 164451.0 True False 211092.50193046793 205152.99591173348 149519.07592840662 198739.4065136793 163783.23104397077 190314.22974906396 189078.88987558943 198393.0146314339 176467.30946811888 194264.66450660035 1.0866232542423886 1.0560489548255605 0.7696668681778026 1.0230342559643775 0.8430932689686654 0.9796646767050002 0.973305620740746 1.0212511633822798 0.9083860408495608 1.0 17.56766398227139 -10.320699240707121 15.1184748068337 0.9999998970998815 0.9602731505991384 0.014173838976874853 0.09278720603284744 0.0 0.0 0.08845814479309042 0.021454251436946632 4.77860088611034e-11 10.320699240707121 -0.03972674650074304 VNNGNTAPEDSS(ph)PAKK ddPTM_PC-9_Lapatinib_30min_R1 3 VNNGNTAPEDSSPAKK 16 1 E9PJ27;G3V167;Q9UGN5-2;Q9UGN5 E9PJ27 PARP2 Poly [ADP-ribose] polymerase 2 1 VNNGNTAPEDS(0.017)S(0.983)PAKK;VNNGNTAPEDS(0.05)S(0.95)PAKK;VNNGNTAPEDS(0.452)S(0.548)PAKK 131.48 4.5963e-06 47144000.0 229644.0 184947.0 167936.0 174353.0 181936.0 155333.0 154468.0 143773.0 158875.0 137325.0 True False 226369.23444844806 184518.7665846099 154128.95033170626 187175.50124455747 171234.88217993852 148689.7696889084 162465.59722227138 150453.21844914078 140980.8244720815 161061.44327593927 1.4054837076097717 1.145642078150773 0.9569574641625689 1.1621372405304862 1.0631649555416536 0.9231866216060473 1.0087181259385987 0.9341355410020517 0.8753232406501253 1.0 17.29725164103121 -1.522878745280374 0.6063630939992017 0.9655678705311692 28.68579021156466 0.7494879816092118 0.07441983247414126 92.61194728071848 0.7016322999039009 0.035146171384062286 3407.686500233338 0.02999999999999748 1.522878745280374 27.72022234103349 VNNS(ph)SLIGLGYTQTLK ddPTM_PC-9_AZD4547_30min_R2 1 VNNSSLIGLGYTQTLK 16 0 P21796 P21796 VDAC1 Voltage-dependent anion-selective channel protein 1 1 VNNS(0.555)S(0.445)LIGLGYTQTLK 52.784 0.044974 25538000.0 51573.0 50174.0 33984.0 51055.0 39425.0 42495.0 46616.0 38230.0 40980.0 41627.0 True False 67972.14121496007 66391.76429395315 33533.34995524884 39285.05854188692 33951.519275036284 39837.780932263886 50764.73369284203 32322.431938004378 43146.119137671885 40169.65140027271 1.6921267386079084 1.652784178592658 0.8347931531967734 0.9779785776687178 0.8452032340715256 0.9917382786148208 1.2637583828396726 0.8046480567114143 1.0740974251367033 1.0 15.293818321010498 -5.253323929722432 24.69439222185135 0.9735706358881712 1.6724556040379146 0.8295139080255401 0.12665256873041583 186.71643974436273 568152.8968134471 0.032197906379717 0.08202357891943439 5.5805380066987355e-06 5.253323929722432 0.6988849681497434 VNPALAELNLR ddPTM_PC-9_Lapatinib_30min_R1 2 VNPALAELNLR 11 0 P13489;E9PMA9;E9PMN0;E9PIK5;E9PMJ3;E9PLZ3;E9PIM9 P13489 RNH1 Ribonuclease inhibitor 0 ; 120.63 0.0027344 4872600.0 16493.6 14669.099999999999 15595.3 12897.3 16560.0 19539.8 17602.5 12958.6 17244.5 14187.2 False True 16258.39823944419 14635.134600216821 14313.11463359889 13845.810466131556 15585.973358212668 18704.128303498524 18513.87132030602 13560.703863695122 15302.242817364648 16639.43861674428 0.9771001662930715 0.8795449736801502 0.860192159319341 0.8321080287046768 0.9366886538184342 1.124084095281709 1.1126499965975716 0.8149736403996812 0.9196369643123651 1.0 14.022319140041601 -6.524750580293565 24.9948750078824 0.9945794710014515 0.8847106025258742 0.24061678157033595 0.08974787607435081 96.86094111198716 1293366.6567734971 0.032353538231152223 0.032564428724611336 2.9870976467339627e-07 6.524750580293565 -0.10986886847557731 VNPHKVS(ph)PASSVDSNIPSSQGYK ddPTM_PC-9_Lapatinib_30min_R1 1 VNPHKVSPASSVDSNIPSSQGYK 23 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 VNPHKVS(0.333)PAS(0.333)S(0.251)VDS(0.082)NIPSSQGYK 52.09 0.0091711 9863700.0 33788.0 50652.0 71066.0 59186.0 77511.0 86940.0 76065.0 76989.0 70281.0 59782.0 True False 33306.176924039675 50534.71840604963 65223.22780269306 63538.73587870811 72951.95537248926 83221.77886703871 80003.27351109653 80566.1900021624 62365.213688260264 70115.23904549227 0.47502051447660204 0.7207380177832898 0.9302289871731712 0.9062043678904498 1.0404579142225625 1.186928547915848 1.1410254689310648 1.149053916080773 0.8894673189061849 1.0 16.097440417309073 -4.645025923962296 0.7715752509308428 1.083427975454195 2.3245334145128046e-08 0.820747425110043 0.08745689990840039 1.2896778149847519 0.508132767078243 0.03541924493940182 1.267627200649301 2.2645091301871595e-05 4.645025923962296 -1.0834279522088608 down VNPHKVS(ph)PASSVDSNIPSSQGYKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VNPHKVSPASSVDSNIPSSQGYKK 24 2 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 VNPHKVS(0.934)PAS(0.026)S(0.026)VDS(0.011)NIPS(0.001)S(0.001)QGYKK 51.175 0.007540899999999999 4504500.0 7289.2 9678.8 10218.0 13886.0 14150.0 17043.0 13364.0 14533.0 11177.0 9753.0 True False 8523.117591737573 10639.647299039198 10461.635871980794 13108.012439019409 11377.409076624917 16149.235077513198 12098.065173018693 14151.52414898633 11340.442480193433 11521.141695294487 0.7397806412899705 0.923488971877213 0.9080381223202539 1.1377355461545133 0.9875244465808216 1.4017044060927517 1.0500752002694174 1.2283091835218165 0.9843158586292835 1.0 13.49199606825031 -5.348197744218128 1.0890266424199548 1.1352421876623149 0.739727188606665 0.46236257271960435 0.1279214294789306 0.6755702136326146 1.1948085425133474 0.0418367340631589 0.24790832400273946 4.4854111239546155e-06 5.348197744218128 -0.3955149990556499 VNPHKVSPAS(ph)SVDSNIPSSQGYK ddPTM_PC-9_AZD4547_30min_R2 1 VNPHKVSPASSVDSNIPSSQGYK 23 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 VNPHKVS(0.015)PAS(0.399)S(0.399)VDS(0.188)NIPSSQGYK 58.479 0.002874 9567500.0 33185.0 37383.0 49396.0 53176.0 43258.0 55511.0 46583.0 54727.0 48495.0 56183.0 True False 43737.13970912015 49466.32368559125 48740.97676522692 40917.09476101026 37252.37338743234 52039.88839465584 50728.79675677147 46270.199651351424 51058.346695495275 54216.050270774285 0.806719403030676 0.9123926113860894 0.8990137887543838 0.7547044566444014 0.6871096880237624 0.9598612981718528 0.9356785767943953 0.8534409906339829 0.9417570339501252 1.0 15.726432393825675 -6.817037649409275 24.999998973659324 0.928833483418518 0.8192161320543286 0.445073091497069 0.06981764951777344 104.76805368126054 47108.49848225191 0.026742210553794776 0.023584427001584304 1.5239206379146435e-07 6.817037649409275 -0.10961735136418937 VNPHKVSPAS(ph)SVDSNIPSSQGYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VNPHKVSPASSVDSNIPSSQGYK 23 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 VNPHKVS(0.035)PAS(0.441)S(0.441)VDS(0.082)NIPSSQGYK 54.117 0.0045513 9542300.0 27643.0 43703.0 41682.0 40072.0 58084.0 33776.0 45189.0 36705.0 28829.0 34256.0 True False 32322.413925863166 48041.54501693499 42675.85695986528 37826.89575517685 46702.857159482795 32004.727100750228 40908.37077997171 35741.532642162194 29250.569585890364 40466.34162965321 0.7987481107552782 1.1871976334458358 1.0546013116390283 0.9347742897385563 1.1541161191912528 0.7908974671754755 1.010923378109243 0.8832410146997638 0.7228370148601703 1.0 15.304434807224307 -6.768838595969919 24.999924731374865 0.8823663262512415 1.0313825384723194 0.23656522394286472 0.12942739443554807 248.78145866531415 840558.9050495956 0.043527250173423945 0.03913929193920789 1.7027912272368052e-07 6.768838595969919 0.14901621222107797 VNPHKVSPAS(ph)SVDSNIPSSQGYK ddPTM_PC-9_Lapatinib_30min_R1 1 VNPHKVSPASSVDSNIPSSQGYK 23 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 VNPHKVS(0.355)PAS(0.52)S(0.119)VDS(0.005)NIPSSQGYK 92.932 0.00062044 0.0 9602.6 12394.0 14087.0 13170.0 20773.0 20635.0 14596.0 16282.0 19014.0 13969.0 True False 9465.665163098827 12365.302454485083 12928.821237392533 14138.565733832082 19551.172981289365 19752.489152534403 15351.70946122351 17038.52116036331 16872.443093703565 16383.523037477506 0.5777551715492452 0.7547401389920413 0.7891355972593744 0.8629746911876001 1.1933436377857083 1.2056313594670907 0.9370212637481139 1.0399790766239647 1.0298421807756273 1.0 13.999958000397823 -5.862847502926005 2.0658667857733075 1.068241506695154 0.6873045261661496 0.7538641213555072 0.09290127834376094 0.16470908688715005 1.4331438598435122 0.030629903759777206 0.05431209447361053 1.3713632186694246e-06 5.862847502926005 -0.3809369805290045 VNPHKVSPASSVDS(ph)NIPSSQGYK ddPTM_PC-9_Lapatinib_30min_R1 1 VNPHKVSPASSVDSNIPSSQGYK 23 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 VNPHKVS(0.043)PAS(0.032)S(0.032)VDS(0.89)NIPS(0.001)S(0.001)QGYK 52.09 0.0091711 6875700.0 33547.0 45236.0 61385.0 47597.0 66905.0 60139.0 59724.0 63518.0 64456.0 48284.0 True False 33068.61362823366 45131.25882129154 56338.16225295239 51097.44215893746 62969.779440290935 57566.99516085617 62816.21648822367 66469.27816385926 57196.28652822957 56629.82506561416 0.5839434183298059 0.7969521143496417 0.9948496607163481 0.9023061981867929 1.1119543344400409 1.016549055098725 1.109242636992815 1.1737503707073897 1.0100028820848215 1.0 15.78927445277313 -4.397894691526442 0.7205548920341779 1.0789862707278106 3.0274826963053064e-18 0.840155138180187 0.06568339697274599 1.6763077075437407 0.44921934657043444 0.02595534097571452 1.6665341980983819 4.0004174081127956e-05 4.397894691526442 -1.0789862707278106 VNPSVNPS(ph)ISPAHGVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VNPSVNPSISPAHGVAR 17 0 B5MCN7;Q15788-2;Q15788-3;Q15788 B5MCN7 NCOA1 Nuclear receptor coactivator 1 1 VNPSVNPS(0.501)IS(0.499)PAHGVAR 107.41 0.0003356 4537300.0 20258.0 18048.0 21047.0 26047.0 28982.0 24251.0 25269.0 21040.0 19419.0 18209.0 True False 23687.27928626183 19839.686164923292 21548.840301191984 24587.671035513376 23303.185149027795 22979.23486855439 22875.337388282656 20487.72229372271 19702.96613786134 21510.147557635297 1.1012141698606681 0.9223407748256449 1.001798813488053 1.1430730993189153 1.083357754129215 1.0682974073972646 1.0634672461911014 0.9524677707964088 0.9159847037342858 1.0 14.392729801099755 -7.765811684795198 24.648153618406948 0.9506696304114128 1.0526736833567791 0.3669262466537725 0.05919884380070789 106.89756140157773 602596.1884742992 0.03309114078866567 0.016786895731084533 1.7147006607448546e-08 7.765811684795198 0.1020040529453663 VNPSVNPSIS(ph)PAHGVAR ddPTM_PC-9_AZD4547_30min_R2 2 VNPSVNPSISPAHGVAR 17 0 B5MCN7;Q15788-2;Q15788-3;Q15788 B5MCN7 NCOA1 Nuclear receptor coactivator 1 1 VNPSVNPS(0.145)IS(0.855)PAHGVAR;VNPSVNPS(0.013)IS(0.987)PAHGVAR 131.41 1.4811e-05 11219400.0 57702.0 47703.0 75031.0 100947.0 74414.0 69931.0 66071.0 73803.0 64367.0 71146.0 True False 76050.03572384053 63122.0618669919 74036.03991561545 77675.228765603 64082.900579138986 65558.20351509933 71951.19100351301 62398.442174222735 67769.30821216505 68655.20019515694 1.1077097657229646 0.9194068575659713 1.07837483111495 1.1313815784500814 0.9334019913565048 0.9548905738931036 1.048007882855006 0.9088669466675655 0.9870965057202705 1.0 16.067081379042463 -6.282783819739861 24.91791683379219 0.9704278560163695 1.050600071083949 0.3076364440891812 0.06351642036611739 1061.0062495612538 1238635.373854 0.019824687385947615 0.022500948190282068 5.214542125727394e-07 6.282783819739861 0.08017221506757943 VNPSVNPSIS(ph)PAHGVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VNPSVNPSISPAHGVAR 17 0 B5MCN7;Q15788-2;Q15788-3;Q15788 B5MCN7 NCOA1 Nuclear receptor coactivator 1 1 VNPSVNPS(0.015)IS(0.985)PAHGVAR 70.501 0.038185000000000004 0.0 28947.0 30606.0 26841.0 34125.0 33102.0 40357.0 32125.0 29564.0 31297.0 25608.0 True False 33847.15537068916 33644.36141199258 27480.99123505935 32213.086884742723 26615.90072469525 38240.60787556182 29081.887435141114 28787.97632564728 31754.65941689309 30250.52768718354 1.1188947089021997 1.1121908933260336 0.908446673037787 1.064876858276779 0.8798491384985592 1.2641302747179348 0.9613679383008729 0.9516520380516895 1.0497224955962277 1.0 14.884672688384379 -5.053609509260767 24.172432718839822 1.012754941205722 1.117219035024703 0.14799899017772433 0.10117149058634496 359.0979353038125 161916.3245958751 0.02489715784044595 0.06587315348309805 8.838742683207684e-06 5.053609509260767 0.10446409381898114 VNPTVFFDIAVDGEPLGR ddPTM_PC-9_Lapatinib_30min_R1 2 VNPTVFFDIAVDGEPLGR 18 0 P62937;F8WE65;C9J5S7;E5RIZ5 P62937 PPIA Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase 0 ; 164.63 7.1083e-07 49991000.0 49521.0 34288.0 54624.0 41463.0 43518.0 53762.0 43908.0 41060.0 45123.0 31908.0 False True 48814.82145896084 34208.60824264845 50133.02557473765 44512.3273365133 40958.35679967986 51462.724585343145 46181.341396506 42967.797496899504 40040.77257374494 37423.25528526252 1.3043980564187951 0.9141002828826593 1.3396222533981512 1.1894295939039405 1.0944626940513504 1.3751536095153496 1.2340279070990507 1.1481576674549863 1.0699436024079179 1.0 15.191647437316817 -8.307369600895164 2.1682037368962073 1.0060859654333403 1.20176069781589 0.23482156581701696 0.12490310295689 0.4566469091961096 4.033940373316517 0.1148934776372202 0.03286645453404483 4.927542730916221e-09 8.307369600895164 0.19567473238254962 VNQIGSVTESLQACK ddPTM_PC-9_AZD4547_30min_R2 2 VNQIGSVTESLQACK 15 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 ; 218.5 2.8918e-17 15592400.0 23404.0 23623.0 32173.0 39370.0 35573.0 32934.0 31277.0 34608.0 25705.0 29674.0 False True 30845.985166558592 31258.67277705698 31746.364998535246 30293.85476043655 30634.30298467639 30874.63177369523 34060.59240842244 29260.12881272444 27063.713822202426 28635.122292062664 1.0772080821568117 1.0916200202756436 1.1086512805756372 1.0579265019878636 1.069815685514564 1.0782084832322625 1.1894690744122876 1.0218265706808252 0.9451230396771934 1.0 14.805498144345636 -7.991997354620532 24.998740932087745 0.9761992623468808 1.0941505464940369 0.6590699053631883 0.03644182580879383 101.98589225922055 318584.32922169316 0.019937565122038814 0.009550145044507649 1.018597592528416e-08 7.991997354620532 0.11795128414715605 VNQIGSVTESLQACK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VNQIGSVTESLQACK 15 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 290.1 7.036999999999998e-89 11709000.0 41493.0 36479.0 36280.0 38832.0 50270.0 43217.0 41247.0 37241.0 34456.0 28617.0 False True 48516.94537589409 40100.394038687744 37145.05279266618 36656.368935042614 40419.95436621442 40950.62444081959 37339.78555758021 36263.46321010113 34959.85381565222 33805.03556795265 1.435198767306975 1.1862254650813955 1.098802357950479 1.0843464093199489 1.1956785043152787 1.2113764636781215 1.1045628241544738 1.072723711152639 1.034161130976426 1.0 15.044950544631117 -4.754898330288105 2.540689002681529 1.110062802687485 1.5188245627026544 0.7274996426121876 0.06150019848840965 0.31743836262060526 2.4688901878999894 0.01692735387454262 0.29226298866447964 1.7583351976117022e-05 4.754898330288105 0.4087617600151694 VNQIGSVTESLQACK ddPTM_PC-9_Lapatinib_30min_R1 2 VNQIGSVTESLQACK 15 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 ; 242.07 2.6261e-32 87331000.0 93229.0 87292.0 87385.0 93586.0 93195.0 90199.0 92716.0 80666.0 77109.0 89348.0 False True 91899.53736389535 87089.8807372043 80200.54261585494 100468.62663374392 87713.45332841972 86341.39903413878 97516.38081712795 84414.03684571094 68424.17242623266 104791.68275127362 0.8769735817872284 0.8310762691340198 0.7653330923811336 0.9587461904988145 0.8370268615364292 0.8239337012945277 0.9305736701316857 0.805541381047104 0.6529542290931581 1.0 16.67716469007491 -7.973462455910194 24.864008911939344 0.794067265170284 0.8579722032557688 0.018526761982311846 0.09434581347415409 497.53113619725826 466155.0690484962 0.04870885851320224 0.0233979603251742 1.0630104749238207e-08 7.973462455910194 0.06390493808548481 VNQSALEAVT(ph)PSPSFQQR ddPTM_PC-9_AZD4547_30min_R2 1 VNQSALEAVTPSPSFQQR 18 0 Q9UKG1 Q9UKG1 APPL1 DCC-interacting protein 13-alpha 1 VNQSALEAVT(0.847)PS(0.149)PS(0.004)FQQR 122.1 0.00014993 9750900.0 5698.6 7829.6 13784.0 21017.0 22175.0 18280.0 15615.0 18089.0 19358.0 23880.0 True False 7510.636261756573 10360.365083827008 13601.215153694393 16171.855359413134 19096.384018362212 17136.94871024317 17004.704749736753 15293.760693867685 20381.224359859727 23043.968468506308 0.3259263382529444 0.4495911846948712 0.5902288562962963 0.7017825675952846 0.8286933756423434 0.7436630862285664 0.737924319458114 0.663677383293131 0.8844494119020474 1.0 14.492101568413933 -5.197987163978719 0.903365302791622 0.7954440390078554 0.21474048548905525 0.7891013696826195 0.08705995725495322 0.5876287951329882 0.5750099570108024 0.03184613995109728 0.29652285022140273 6.338884462067885e-06 5.197987163978719 -0.5807035535188002 down VNQSALEAVT(ph)PSPSFQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VNQSALEAVTPSPSFQQR 18 0 Q9UKG1 Q9UKG1 APPL1 DCC-interacting protein 13-alpha 1 VNQSALEAVT(0.667)PS(0.327)PS(0.006)FQQR;VNQSALEAVT(0.879)PS(0.113)PS(0.007)FQQR 180.76 1.7609e-08 26353700.0 25807.0 31069.0 46028.0 57559.0 75142.0 59430.0 56431.0 51411.0 46240.0 48188.0 True False 30175.61538851608 34153.32499213219 47125.48208216207 54334.155838795785 60418.46451136037 56313.38617946431 51085.44715494002 50061.51572445717 46916.1725225145 56924.102944001905 0.5301026072945025 0.5999800300011742 0.8278651686179568 0.954501749324817 1.0613863264704582 0.9892713853543134 0.8974308686988786 0.8794432083313515 0.8241881750629864 1.0 15.796752030936606 -5.319789077339244 2.2724139907818137 0.9432067668229055 0.5345967474483603 0.8476410197863136 0.06368592857281062 0.1284844643219499 1.2492113532724798 0.020093223189493015 0.06465331567427281 4.788626037999492e-06 5.319789077339244 -0.4086100193745452 VNQSALEAVTPS(ph)PSFQQR ddPTM_PC-9_AZD4547_30min_R2 3 VNQSALEAVTPSPSFQQR 18 0 Q9UKG1 Q9UKG1 APPL1 DCC-interacting protein 13-alpha 1 VNQSALEAVT(0.284)PS(0.634)PS(0.081)FQQR;VNQSALEAVT(0.316)PS(0.658)PS(0.025)FQQR;VNQSALEAVT(0.004)PS(0.978)PS(0.018)FQQR 194.15 1.9983e-14 50958800.0 30923.1 31260.8 58082.0 83310.0 86821.0 79442.0 65390.0 88003.0 62764.0 78848.0 True False 40756.002559562825 41365.2422617374 57311.794729895344 64104.1666266693 74767.40278954801 74474.47918157217 71209.58332278483 74404.15845776092 66081.57690475434 76087.5555194633 0.5356461024580739 0.5436531897933837 0.753234800863525 0.8425052715784956 0.9826495578560466 0.9787997350305399 0.9358900129807604 0.9778755270791717 0.8684938877797248 1.0 16.215372892956665 -5.539570950635354 1.4366347323375839 0.956101122728664 0.5087027288354059 0.9437500512099759 0.03984064067067326 0.09491371438575619 0.3669570524472956 0.012389136670113501 0.04029502063472422 2.886882111091249e-06 5.539570950635354 -0.4473983938932581 VNQSALEAVTPS(ph)PSFQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VNQSALEAVTPSPSFQQR 18 0 Q9UKG1 Q9UKG1 APPL1 DCC-interacting protein 13-alpha 1 VNQSALEAVT(0.002)PS(0.992)PS(0.007)FQQR;VNQSALEAVTPS(0.997)PS(0.003)FQQR 222.13 1.7739e-28 24534600.0 34504.0 37082.0 57141.0 72974.0 100185.0 83058.0 67761.0 64862.0 63352.0 58903.0 True False 40344.84571493625 40763.25589359962 58503.45814844924 68885.50336490019 80554.46843404014 78702.29226474742 61342.18753284344 63159.44122696973 64278.40314979105 69581.64762410859 0.5798202125492298 0.5858334386361383 0.8407886295606919 0.9899952892324555 1.1576970535277997 1.1310783080318827 0.8815857288149304 0.9077025822694992 0.9237838617595471 1.0 16.08641922049328 -5.426678532428573 2.4227282980720797 1.0021091601542997 0.5705183838613542 0.7926223248747307 0.08441138244436784 0.14621005743533147 1.649505206525764 0.027537118030789277 0.07250557870194396 3.7438760985188955e-06 5.426678532428573 -0.4315907762929455 VNQSALEAVTPS(ph)PSFQQR ddPTM_PC-9_Lapatinib_30min_R1 4 VNQSALEAVTPSPSFQQR 18 0 Q9UKG1 Q9UKG1 APPL1 DCC-interacting protein 13-alpha 1 VNQSALEAVT(0.04)PS(0.832)PS(0.127)FQQR;VNQSALEAVT(0.009)PS(0.94)PS(0.051)FQQR;VNQSALEAVT(0.001)PS(0.999)PSFQQR;VNQSALEAVT(0.002)PS(0.977)PS(0.021)FQQR 234.51 3.1501999999999997e-43 62464100.0 120947.0 100400.0 103144.0 102693.0 99531.0 98237.0 79969.0 76491.0 101150.0 62339.0 True False 119222.27360103655 100167.52996855753 94663.89846735391 110245.38579380534 93676.78226547495 94035.63251163182 84109.40352867793 80045.05110412427 89757.42184327947 73114.21308850386 1.6306306060727132 1.3700144710209212 1.2947400302696879 1.5078516356368992 1.2812390137069567 1.286147091507404 1.1503837622770352 1.0947946742889882 1.2276330148644177 1.0 16.1578642667 -1.522878745280338 0.13459114253085713 0.9101918057312571 3.097963429214509 0.7610120462476131 0.08680225173796084 39.57351944569611 0.3591951660327508 0.4313098440772035 16.523027727730184 0.029999999999999964 1.522878745280338 2.187771623483252 VNS(ph)GDTEVGSSLLR ddPTM_PC-9_AZD4547_30min_R2 2 VNSGDTEVGSSLLR 14 0 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 VNS(0.998)GDT(0.002)EVGSSLLR;VNS(0.894)GDT(0.076)EVGS(0.015)S(0.015)LLR 94.007 0.0035527 37795600.0 18382.4 23457.7 28292.3 31824.1 26155.6 28088.8 25252.2 32772.0 23773.7 27996.2 True False 24227.62082232727 31039.942784674666 27917.125616139576 24487.54542244369 22524.346418519704 26332.402895638876 27499.596880006542 27707.84042564162 25030.329247029524 27016.06155938009 0.896785816432793 1.1489440352528908 1.0333529021163572 0.9064069301375097 0.8337390840264486 0.9746943623800026 1.0178980685087522 1.0256062070609748 0.9264980830760243 1.0 14.721529751367234 VNS(ph)GDTEVGSSLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VNSGDTEVGSSLLR 14 0 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 VNS(0.502)GDT(0.493)EVGS(0.003)S(0.001)LLR;VNS(0.853)GDT(0.147)EVGSSLLR 115.66 0.0001558 17474200.0 27034.4 32885.4 32934.6 33697.6 40942.0 33216.0 44858.0 46495.0 42998.0 34368.0 True False 31610.78996626108 36150.04517996277 33719.88576916603 31809.63272109324 32919.70900460617 31474.094486573893 40608.7254962042 45274.55551552462 43626.764405775895 40598.646343061686 0.7786168459693821 0.8904248894037526 0.8305667505322814 0.7835146140661784 0.8108573060892744 0.7752498499732078 1.0002482632809317 1.115174016713541 1.0745866755538196 1.0 15.30914400482421 -7.396207293646726 4.0038867179559166 1.0694683448131383 0.8150612642885339 0.8857132994854225 0.04184390938024296 0.07284460853901466 1.9977896371891481 0.018863218231588694 0.012182455764196305 4.015990773323497e-08 7.396207293646726 -0.2544070805246045 VNS(ph)GDTEVGSSLLR ddPTM_PC-9_Lapatinib_30min_R1 2 VNSGDTEVGSSLLR 14 0 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 VNS(0.797)GDT(0.161)EVGS(0.021)S(0.021)LLR;VNS(0.999)GDT(0.001)EVGSSLLR 207.05 7.5512e-11 19406000.0 27527.0 30769.0 30254.0 26294.0 41982.0 53497.0 52784.0 53629.0 62714.0 42153.0 True False 27134.459932166454 30697.756270941718 27766.632903817255 28227.74847421268 39512.70129978771 51209.05801759793 55516.89724590447 56120.799122289885 55650.48891230282 49439.08988465811 0.5488462671030437 0.6209207398954935 0.5616331726291298 0.5709601155698517 0.7992198358014121 1.035800985355296 1.1229352598404612 1.1351503284793525 1.1256374063951413 1.0 15.593364564721837 -6.60587650761061 2.0309168914558153 1.1074167343544232 0.5745041437805266 0.9707136470365032 0.04176216537610696 0.047172041577127066 0.39657277488722786 0.015500801558179435 0.01583849817767783 2.478126617060073e-07 6.60587650761061 -0.5329125905738966 VNS(ph)PGTLAR ddPTM_PC-9_AZD4547_30min_R2 2 VNSPGTLAR 9 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6;P53814-2 A0A087WVP4 SMTN Smoothelin 1 VNS(0.845)PGT(0.155)LAR;VNS(0.827)PGT(0.173)LAR 87.713 0.010678 16141100.0 54936.0 54167.0 66161.0 92805.0 84761.0 73312.0 64356.0 79668.0 73885.0 75292.0 True False 72404.50526021475 71675.42345658228 65283.66191117062 71410.24107295687 72993.39823135962 68727.78905062075 70083.55932590824 67357.14118851525 77790.41026078294 72656.04999710117 0.9965378693598611 0.9865031674505012 0.8985302932622308 0.9828533353493066 1.004643085252665 0.9459334639491528 0.964593579319333 0.9270685812289914 1.0706666583703162 1.0 16.148795314192242 -8.261938583132096 24.999809605190492 1.0353333290875502 0.9634349016806069 0.4078441164665204 0.03470272746052465 43.89111343814906 2197713.510421442 0.027424018388721376 0.008699470696389999 5.470933260293074e-09 8.261938583132096 -0.0718984274069433 VNS(ph)PGTLAR ddPTM_PC-9_Lapatinib_30min_R1 3 VNSPGTLAR 9 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6;P53814-2 A0A087WVP4 SMTN Smoothelin 1 VNS(0.836)PGT(0.164)LAR;VNS(0.98)PGT(0.02)LAR;VNS(0.98)PGT(0.02)LAR 101.39 0.0035126999999999997 20865000.0 118684.0 113297.0 111584.0 106230.0 126258.0 104916.0 100086.0 97461.0 105992.0 86040.0 True False 116991.54439601976 113034.66775744708 102409.99424669618 114042.50857289146 118831.75267277854 100428.98725114139 105267.96335544084 101989.39385887314 94054.06481475913 100911.89935890648 1.1593433989377595 1.1201321992307802 1.0148455722001777 1.130119532953039 1.1775791896467804 0.9952145177047204 1.0431670003657492 1.0106775762502935 0.9320413688800311 1.0 16.622736779048417 -6.7806613433389895 24.971721077179133 0.999821578488223 1.1150642738144299 0.6273621403195333 0.047725244072860815 182.1274378024547 236604.53782877105 0.01773947445728674 0.015668506616268386 1.657061612880281e-07 6.7806613433389895 0.1152426953262069 VNS(ph)QPGPQK ddPTM_PC-9_AZD4547_30min_R2 2 VNSQPGPQK 9 0 Q8TF42 Q8TF42 UBASH3B Ubiquitin-associated and SH3 domain-containing protein B 1 VNS(1)QPGPQK;VNS(1)QPGPQK 93.839 0.0059464 11209300.0 62855.0 72810.0 52870.0 78550.0 67400.0 76751.0 103468.0 113011.0 114955.0 77102.0 True False 82841.58253478215 96344.40862284727 52168.90925535567 60441.51108540233 58042.67340868607 71951.74783697352 112676.45155592466 95547.74668443155 121031.2866147161 74402.68244802224 1.1134219870722448 1.2949050417658468 0.7011697366126671 0.8123566126480293 0.7801153331969545 0.9670585181823121 1.5144138335958586 1.2841976060632123 1.626705955114839 1.0 16.183067015462008 -7.224834605195863 9.531046819994133 1.3799115320616904 0.9358236768958771 0.4524750665992626 0.22101688095934022 0.4509715978258337 114.84481968178201 0.08676863019741447 0.06682241465923303 5.958890360867129e-08 7.224834605195863 -0.4440878551658133 VNS(ph)QPGPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VNSQPGPQK 9 0 Q8TF42 Q8TF42 UBASH3B Ubiquitin-associated and SH3 domain-containing protein B 1 VNS(1)QPGPQK 120.06 0.0003494 0.0 31456.0 38969.0 22267.0 23549.0 45545.0 25059.0 36554.0 44764.0 35370.0 29847.0 True False 36780.87951568033 42837.584782851045 22797.929728067753 22229.62587688811 36620.78419751814 23744.861926151687 33091.34049195791 43588.99243137849 35887.21933653412 35258.024831277995 1.0431917185290365 1.214974037480656 0.6466025773469681 0.6304841517148128 1.0386510410824608 0.6734597879427214 0.9385477675029039 1.23628571481151 1.0178454269139308 1.0 15.105664036115213 -7.546416133477683 15.139948784354953 1.0937494116997204 0.8702016229647359 0.19721890084400107 0.18926281214005458 4.753010733467228 3052.039043706565 0.09338902376345633 0.05399459634926991 2.8417368992563726e-08 7.546416133477683 -0.2235477887349845 VNS(ph)QPGPQKR ddPTM_PC-9_Lapatinib_30min_R1 1 VNSQPGPQKR 10 1 Q8TF42 Q8TF42 UBASH3B Ubiquitin-associated and SH3 domain-containing protein B 1 VNS(1)QPGPQKR 80.834 0.025138 1602500.0 8415.7 8553.0 6780.8 4115.3 12594.0 7222.4 11467.0 8489.7 8442.1 11144.0 True False 8295.690574749635 8533.196053994749 6223.308798644942 4417.95289023836 11853.245680756661 6913.514788236715 12060.705151538077 8884.162455173591 7491.261798745919 13070.225551553394 0.6347014090941754 0.652872899579042 0.4761439482507861 0.33801657613424174 0.9068891454094229 0.5289514523653377 0.9227618225842066 0.679725259532167 0.5731547454324982 1.0 13.673996417339247 -6.266987867984342 24.99752883722326 0.7482942840220844 0.5310158115495932 0.34175394989413654 0.16379663950505174 594.0988625599599 2676580.3883197815 0.04959851381256608 0.0578162010438484 5.407694291277234e-07 6.266987867984342 -0.2172784724724912 VNSGDT(ph)EVGSSLLR ddPTM_PC-9_AZD4547_30min_R2 1 VNSGDTEVGSSLLR 14 0 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 VNS(0.002)GDT(0.954)EVGS(0.027)S(0.017)LLR 168.68 0.00083541 29060000.0 16675.0 18693.0 18569.0 15016.0 21365.0 17757.0 17180.0 17855.0 14216.0 15912.0 True False 21977.30313845347 24735.146688461504 18322.76292723093 11554.29319488735 18398.838536744468 16646.651982920564 18708.986717930027 15095.920017082613 14967.428737460792 15354.92572323586 1.4312868414072684 1.6108932816933796 1.1932824200838685 0.7524812169819097 1.1982368959885232 1.08412455279611 1.2184355076116475 0.9831320769099322 0.9747639947753908 1.0 13.90641391309551 -5.419407794334921 4.663533449257114 1.0417472531518825 1.5137371373595907 0.6875385601393128 0.13032291305804614 0.1217471644604665 4.2310173317194 0.0347174907014263 0.07478264854144476 3.8070817770374276e-06 5.419407794334921 0.47198988420770815 VNSGDT(ph)EVGSSLLR ddPTM_PC-9_Lapatinib_30min_R1 1 VNSGDTEVGSSLLR 14 0 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 VNS(0.102)GDT(0.898)EVGS(0.001)SLLR 191.15 3.8962e-06 21202000.0 9725.2 11467.0 7344.3 10820.0 13248.0 16223.0 25130.0 18365.0 18225.0 17625.0 True False 9586.51686461675 11440.448866030372 6740.480003817841 11615.738894461898 12468.778686570124 15529.180107660082 26431.10843796566 19218.30494472867 16172.308582241905 20671.45776616372 0.46375620786205674 0.5534418034492364 0.326076664745486 0.5619216131663068 0.6031881654219746 0.7512377831949121 1.2786281807966966 0.9297024506992604 0.7823496903403546 1.0 14.335352511798874 -6.841092686187092 2.4420975412449746 0.9932649994693573 0.48414239284857236 0.7482513566094403 0.13521673315526536 0.14681941159021109 1.787948039520416 0.05425886279413824 0.04777237916054193 1.4418076112318095e-07 6.841092686187092 -0.509122606620785 down VNSNGKES(ph)PGSSEFFQEAVSHGK ddPTM_PC-9_AZD4547_30min_R2 1 VNSNGKESPGSSEFFQEAVSHGK 23 1 Q8N108-17;Q8N108;Q8N108-13;Q8N108-12 Q8N108-17 MIER1 Mesoderm induction early response protein 1 1 VNS(0.156)NGKES(0.647)PGS(0.156)S(0.041)EFFQEAVSHGK 42.638999999999996 0.034731 5121200.0 23347.0 28700.0 26246.0 23496.0 26504.0 27177.0 27441.0 25702.0 26192.0 23190.0 True False 30770.860352232263 37976.7137409108 25897.960891168255 18079.360209581326 22824.377092341463 25477.617893778912 29883.195839739088 21730.346473203987 27576.455647972205 22378.12515848665 1.3750419275210266 1.6970462660277223 1.1572891253290156 0.8079032573792239 1.0199414352495735 1.138505469664728 1.3353753108493194 0.9710530403822949 1.232295174536288 1.0 14.449801551795131 -5.375367115617087 5.683302428305343 1.0760170670424458 1.531867017265288 0.5802326739459333 0.15525098876983698 0.14912437464533124 6.38034366953289 0.04156973412700029 0.08843072812521184 4.21340187691732e-06 5.375367115617087 0.45584995022284214 VNSPGT(ph)LAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VNSPGTLAR 9 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6;P53814-2 A0A087WVP4 SMTN Smoothelin 1 VNS(0.09)PGT(0.91)LAR;VNS(0.054)PGT(0.946)LAR 96.171 0.012691 13022600.0 80388.0 72669.0 84477.0 82409.0 102052.0 91419.0 98007.0 94117.0 69866.0 55880.0 True False 93996.1006646273 79883.09806731014 86491.25206080666 77791.89090358275 82055.6431864115 86624.82670604829 88723.06745076671 91646.52847520461 70887.65807651392 66010.6016541633 1.4239546119740443 1.2101555820658378 1.3102630470472563 1.178475713812501 1.2430676456534955 1.3122865802660784 1.3440730008127555 1.38836075082834 1.073882926380554 1.0 16.01041012713562 -8.409653729144717 4.8440412832101964 1.0034927465435999 1.2936866654091324 0.6835536208536919 0.0724797260574122 0.1231769958789357 4.070963689515698 0.070928050492066 0.018498533142130718 3.893554614278196e-09 8.409653729144717 0.2901939188655325 VNSPGT(ph)LAR ddPTM_PC-9_Lapatinib_30min_R1 1 VNSPGTLAR 9 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6;P53814-2 A0A087WVP4 SMTN Smoothelin 1 VNS(0.01)PGT(0.99)LAR 108.47 0.00595 5225600.0 37145.0 40321.0 41614.0 43508.0 41123.0 38197.0 32725.0 38718.0 40224.0 30764.0 True False 36615.305488441256 40227.63920181484 38192.65755468534 46707.72345843333 38704.22599092869 36563.40335155597 34419.34037534526 40516.97962700818 35693.549542501976 36081.5164095467 1.0147939757530071 1.114909881979659 1.0585103220489942 1.2945055559271084 1.072688452215053 1.013355506917713 0.9539327556155137 1.1229289580603081 0.9892474899712899 1.0 15.138972352027455 -6.522418577998685 22.47039126399846 1.0222943539571017 1.1242983223080276 0.2815528992751667 0.07864322995410346 6.35042282090637 310175.6291526034 0.025951590375955954 0.02631554445093517 3.003180407610615e-07 6.522418577998685 0.10200396835092596 VNVGAGSHPNK ddPTM_PC-9_AZD4547_30min_R2 1 VNVGAGSHPNK 11 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 85.963 0.0093806 4016000.0 38878.0 36413.0 60491.0 74752.0 58003.0 54294.0 53701.0 82695.0 54964.0 57716.0 False True 51240.39528736394 48182.790154975075 59688.84981588271 57519.08130688722 49950.284654658964 50898.98759704282 58480.28496737839 69916.38789205538 57869.28482877004 55695.38040738314 0.9200115864649228 0.8651128657806568 1.0717019863997588 1.0327442040284964 0.8968478945524432 0.9138816760877263 1.0500024335882996 1.2553354942663622 1.0390320418944248 1.0 15.765270049309581 -7.517352037264204 24.923745001524136 1.1188440573208402 0.9554663106624318 0.3791093229508261 0.0855526552793627 232.65972582428213 1049239.0747605076 0.03944294230717179 0.02366774926173649 3.0384210959381574e-08 7.517352037264204 -0.16337774665840843 VNVGAGSHPNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VNVGAGSHPNK 11 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 108.31 0.0018471 2879500.0 46320.0 61154.0 53693.0 44928.0 69407.0 45850.0 58774.0 49432.0 49276.0 39936.0 False True 54161.06113829837 67224.96496729394 54973.24475183642 42410.829818541286 55807.196592318425 43445.54528568799 53206.501233088944 48134.46237753332 49996.56827896679 47176.080666797956 1.1480619070675868 1.4249798630390715 1.1652779114931018 0.8989901072555524 1.1829553410017581 0.9209231600340323 1.1278279263782744 1.0203149921992112 1.0597863911605923 1.0 15.525767945701046 -5.523622386257588 24.991634216967213 1.036487794048186 1.2886729031721857 0.511745959203459 0.10126368716778672 16.45668252829981 553056.1101130507 0.024879073320432564 0.04358926264967008 2.994867505544229e-06 5.523622386257588 0.2521851091239997 VNVGAGSHPNK ddPTM_PC-9_Lapatinib_30min_R1 2 VNVGAGSHPNK 11 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 123.11 0.00050592 18643400.0 98856.0 118695.0 133164.0 126281.0 109846.0 119058.0 108136.0 100369.0 134000.0 108799.0 False True 97446.29531202969 118420.1690200991 122215.76994790521 135568.12600106685 103385.07424554529 113966.16687775342 113734.75296648825 105032.51015504892 118907.50891744389 127604.76218444495 0.7636571993385088 0.9280231160098079 0.9577680946675777 1.062406478255971 0.8101976170458939 0.8931184457914058 0.891304924827896 0.8231080749418332 0.9318422516674597 1.0 16.961322645637402 VNVPVIGGHAGK ddPTM_PC-9_AZD4547_30min_R2 1 VNVPVIGGHAGK 12 0 P40926;G3XAL0;P40926-2 P40926 MDH2 Malate dehydrogenase, mitochondrial;Malate dehydrogenase 0 83.182 0.009485200000000001 4187400.0 31035.0 33904.0 35190.0 49913.0 46591.0 41848.0 26075.0 42737.0 32057.0 34306.0 False True 40903.48443189825 44862.80497114424 34723.35760726246 38406.32899816279 40122.643869200154 39231.23794454355 28395.624486031757 36132.978648561184 33751.467574337425 33104.95738193373 1.2355697655789881 1.3551687879721328 1.048886944836 1.1601383005894508 1.2119829488466933 1.1850562890605953 0.857745387146398 1.0914673059896438 1.0195291051109014 1.0 15.014759652618462 -7.141481540521011 8.203930696516633 1.0001578649998721 1.1996890376134866 0.5661430523777109 0.08885794360716609 0.23722946069335976 15.011577464571124 0.03478325102920769 0.026932468414182332 7.219688492252196e-08 7.141481540521011 0.19953117261361442 VNVPVIGGHAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VNVPVIGGHAGK 12 0 P40926;G3XAL0;P40926-2 P40926 MDH2 Malate dehydrogenase, mitochondrial;Malate dehydrogenase 0 ; 108.98 0.00090015 3180200.0 89618.0 85767.0 88026.0 110788.0 118558.0 94640.0 100050.0 99965.0 78232.0 73478.0 False True 104788.55736381737 94281.38094564374 90124.8736804639 104580.90753954204 95327.4109757242 89676.91179580189 90572.53970072728 97341.0246716727 79375.99499959654 86798.97974847216 1.2072556344265308 1.0862037920129273 1.0383172007508565 1.2048633272257196 1.098254970875993 1.0331562888834576 1.0434747040021695 1.1214535580227958 0.914480737326797 1.0 16.4053904646101 -7.433408894013861 0.576743019982268 0.9807912603199823 1.1330421821278793 0.40792935481229886 0.06559017354154356 0.9232980056363702 0.6337549933037165 0.06187592555790935 0.043033517514336164 3.6863036475638046e-08 7.433408894013861 0.152250921807897 VNVTVDYIRPAS(ph)PATETVPAFSER ddPTM_PC-9_AZD4547_30min_R2 2 VNVTVDYIRPASPATETVPAFSER 24 1 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 1 VNVT(0.007)VDY(0.048)IRPAS(0.658)PAT(0.141)ET(0.141)VPAFS(0.006)ER;VNVT(0.093)VDY(0.146)IRPAS(0.381)PAT(0.165)ET(0.214)VPAFSER 51.001000000000005 0.011537 75384000.0 26952.9 29480.0 34937.0 49669.0 39608.0 39246.0 33223.0 39498.0 32805.8 34924.0 True False 35523.3615448529 39008.83348717945 34473.71255256973 38218.579428400386 34109.11288384624 36791.941415875466 36179.7826385209 33394.491673745666 34539.84761363193 33701.321390038276 1.054064353552416 1.1574867654509835 1.0229187204143206 1.1340380095510842 1.0121001633463695 1.0917061972160753 1.0735419605598975 0.9908956176304913 1.0248811081882834 1.0 15.040517538478294 -7.731582832539408 8.903759143509875 1.0059293671070884 1.0791620389419334 0.3781666796484646 0.04271380247892017 0.25414518232062505 69.89061105152597 0.01915802468649249 0.010858027084948527 1.855312913763656e-08 7.731582832539408 0.07323267183484505 VNVTVDYIRPAS(ph)PATETVPAFSER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VNVTVDYIRPASPATETVPAFSER 24 1 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 1 VNVTVDY(0.006)IRPAS(0.641)PAT(0.092)ET(0.241)VPAFS(0.02)ER;VNVT(0.002)VDY(0.008)IRPAS(0.888)PAT(0.048)ET(0.048)VPAFS(0.006)ER 57.216 0.0030642 38236000.0 43169.8 58363.0 48572.0 49075.0 57642.0 47100.5 50567.0 50894.1 46620.5 42609.6 True False 50477.594497584454 64156.89293237023 49730.140690335764 46325.4868532967 46347.46388655925 44630.46686430854 45776.92768662349 49558.18380175636 47302.23661517918 50334.383182592006 1.002845198568798 1.2746136711288576 0.9879954326635075 0.9203547142963348 0.920791334989248 0.8866795228702405 0.9094564151221247 0.9845791418955125 0.9397599339518382 1.0 15.61925661458767 -5.462396257872861 7.2382995437030955 0.9342477113099787 1.1385889103117757 0.5722547182574765 0.06862509020291167 0.16322935066157224 16.903716339264857 0.01680179879219937 0.034935554398003374 3.448289677814395e-06 5.462396257872861 0.20434119900179692 VNVTVDYIRPAS(ph)PATETVPAFSER ddPTM_PC-9_Lapatinib_30min_R1 1 VNVTVDYIRPASPATETVPAFSER 24 1 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 1 VNVTVDY(0.003)IRPAS(0.548)PAT(0.318)ET(0.125)VPAFS(0.006)ER 68.406 0.00045486 22944000.0 25783.0 29422.0 31149.0 24167.0 32520.0 28421.0 28234.0 35304.0 36686.0 23737.0 True False 25415.32969197688 29353.875166682294 28588.049458617148 25944.32179874869 30607.23753677995 27205.500082586892 29695.818369977016 36944.35272358843 32554.03635929366 27839.908822435653 0.9129099471581297 1.0543811531101914 1.026872955689373 0.9319111626486598 1.099401500629706 0.9772122551156668 1.0666636359830934 1.327028510014935 1.169329848273748 1.0 14.764866865821029 -7.535544871891736 24.33321847931026 1.1882768228452667 1.0068545568483707 0.3926507316398009 0.09033515322552889 145.67526594066638 279855.3885165924 0.03983987132937384 0.023022205408289018 2.913769064667133e-08 7.535544871891736 -0.18142226599689604 VNVTVDYIRPASPAT(ph)ETVPAFSER ddPTM_PC-9_Lapatinib_30min_R1 1 VNVTVDYIRPASPATETVPAFSER 24 1 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 1 VNVTVDYIRPAS(0.275)PAT(0.519)ET(0.202)VPAFS(0.003)ER 69.149 0.00063302 22919000.0 34833.0 30649.0 41808.0 39252.0 38545.0 41935.0 34095.0 38825.0 41570.0 37844.0 True False 34336.27503241016 30578.03412356895 38370.707623547016 42138.723020833495 36277.8588823857 40141.537805259526 35860.272271883754 40628.95123763089 36887.94884849363 44385.284976039715 0.7735959124954529 0.6889227846588286 0.8644916360064036 0.9493849829640844 0.817339776053469 0.904388421228543 0.8079315541455242 0.9153698406930003 0.8310850965225675 1.0 15.437793839666007 -5.328146558343707 6.334021945503855 0.8815623986605615 0.7317444179691779 0.5148079256823491 0.06013054475031398 0.15613813476068403 11.85112200936439 0.014585764581285765 0.03102517356844239 4.697355634557071e-06 5.328146558343707 -0.14981798069138363 VPAAFPTKVPVPGPGS(ph)GGNGPER ddPTM_PC-9_AZD4547_30min_R2 2 VPAAFPTKVPVPGPGSGGNGPER 23 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 VPAAFPTKVPVPGPGS(1)GGNGPER;VPAAFPT(0.002)KVPVPGPGS(0.998)GGNGPER 72.051 0.00035453 127123000.0 103277.0 70976.0 129784.0 183871.0 152537.0 112768.0 91228.0 136483.0 87213.0 125691.0 True False 136116.9377049512 93917.60398867191 128062.97936064085 141482.38172863168 131359.87053027825 105716.59913329872 99347.11526794662 115392.68841733331 91822.90113113176 121290.59634736272 1.122238176776108 0.7743189234530794 1.055836010517112 1.1664744505290578 1.0830177646590033 0.8715976532140891 0.8190834100891679 0.951373741183212 0.7570488058955637 1.0 16.888108177171233 -6.772280122473622 24.81359602016049 0.8729854529038267 1.0334602950891323 0.3226328898612457 0.11589272465911919 251.6371231948894 575973.7306119784 0.04159011078077968 0.03704583485289717 1.6893509389473587e-07 6.772280122473622 0.1604748421853056 VPAAFPTKVPVPGPGS(ph)GGNGPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VPAAFPTKVPVPGPGSGGNGPER 23 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 VPAAFPTKVPVPGPGS(1)GGNGPER;VPAAFPTKVPVPGPGS(1)GGNGPER 98.96700000000001 3.1843e-06 106495000.0 90752.0 41044.0 72108.0 100478.0 118931.0 125407.0 100482.0 119924.0 99672.0 99134.0 True False 106114.52116629634 45118.57706965377 73827.3281911129 94848.54341407133 95627.32430332694 118830.43615359388 90963.6175333183 116776.12206998098 101129.51443910155 117106.20945568758 0.9061391506011435 0.3852791178142131 0.6304305171712419 0.8099360730308802 0.8165862830656461 1.0147236146223206 0.7767616931341159 0.9971812990340917 0.8635708978127967 1.0 16.837458049963544 -5.991180804043537 2.0460133491616856 0.913210793137472 0.6141617454490168 0.42973954089112476 0.13881938191762194 0.2810847848716124 2.3657473158696054 0.042369667529187326 0.06752197245194205 1.0205145380177494e-06 5.991180804043537 -0.2990490476884552 VPAAFPTKVPVPGPGS(ph)GGNGPER ddPTM_PC-9_Lapatinib_30min_R1 2 VPAAFPTKVPVPGPGSGGNGPER 23 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 VPAAFPTKVPVPGPGS(1)GGNGPER;VPAAFPTKVPVPGPGS(1)GGNGPER 74.703 0.0001975 88137000.0 189551.0 111494.0 137879.0 113756.0 98329.0 116641.0 73736.0 72172.0 126014.0 77211.0 True False 186847.96798060363 111235.84249317071 126543.1208483313 122121.99571889197 92545.48154225202 111652.53633345127 77553.68928698104 75525.37459683965 111820.97633375209 90556.81847280926 2.0633230178764164 1.2283541357691423 1.397389208039893 1.3485676482280626 1.021960390205624 1.2329555986662257 0.8564091649296119 0.8340109101725678 1.234815646348349 1.0 16.466535652492553 -1.5228787452804797 0.5132249970536914 1.0104576040623656 33.27824170238977 0.7273363535714175 0.17540794757696038 60.967496764286835 0.6241618308731788 0.0940020666469788 2134.6761366073247 0.02999999999999018 1.5228787452804797 32.267784098327404 up VPADTEVVCAPPTAYIDFAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VPADTEVVCAPPTAYIDFAR 20 0 P60174;P60174-3 P60174 TPI1 Triosephosphate isomerase 0 ;; 136.14 7.4771e-05 11954400.0 14228.900000000001 16303.2 15708.9 26861.5 21192.9 20943.9 15886.8 14325.8 20238.2 15056.130000000001 False True 16637.57173641479 17921.67395190478 16083.459752335011 25356.537241158003 17040.303379505596 19845.565014371223 14381.887293528387 13949.76292943978 20534.145388087218 17785.687184740502 0.9354472258282629 1.0076458539808881 0.9042922876847883 1.4256709329124504 0.958090806529285 1.115816600631435 0.808621401250526 0.7843252152443223 1.1545320220016462 1.0 14.118429096364999 -7.247086736750324 24.864775331566307 0.9188967534612558 1.0607541372514482 0.10690833166711311 0.16796142664968192 1525.477782904765 2642768.5388569287 0.06449615337820594 0.049728596009267385 5.661262117284071e-08 7.247086736750324 0.14185738379019242 VPADTEVVCAPPTAYIDFAR ddPTM_PC-9_Lapatinib_30min_R1 4 VPADTEVVCAPPTAYIDFAR 20 0 P60174;P60174-3 P60174 TPI1 Triosephosphate isomerase 0 ;;; 190.24 2.6822000000000002e-11 58191000.0 48185.0 41341.600000000006 50553.7 42878.9 47850.6 46444.9 49846.6 42522.8 42006.4 43238.7 False True 47497.87306395324 41245.87606522031 46397.3699289253 46032.35734581723 45036.12178589922 44458.55989534992 52427.41304671304 44498.56452511347 37275.19688499788 50712.451683053776 0.9366116503459301 0.8133283778706198 0.9149108037391452 0.9077131122256419 0.8880683203282917 0.8766793641374339 1.0338173625360798 0.8774682163509606 0.7350304638782406 1.0 15.630052402435236 VPAINVNDSVTK ddPTM_PC-9_Lapatinib_30min_R1 2 VPAINVNDSVTK 12 0 P23526;P23526-2 P23526 AHCY Adenosylhomocysteinase 0 ; 163.12 0.00042755 12213200.0 52813.0 45510.0 52892.0 46798.0 44394.0 54287.0 49605.0 37506.0 50725.0 40234.0 False True 52059.87693528198 45404.62439112608 48543.42392902434 50239.68103355159 41782.832201962156 51965.27155917792 52173.30418087091 39248.66568238462 45011.816342069695 47188.393291564906 1.103234785164594 0.9621989905564834 1.0287153374578162 1.0646618273933077 0.885447231563847 1.1012299409750597 1.105638495858622 0.8317440570582101 0.9538747391536155 1.0 15.52614442981731 -7.7574066690212735 24.999848656460227 0.9196070542726387 1.0306012691677577 0.2900232521004735 0.07626540034054213 124.34099203431123 770838.2225763684 0.03681090555141291 0.02024235564659718 1.7482089165544936e-08 7.7574066690212735 0.11099421489511907 VPAPFS(ph)PPPSKPR ddPTM_PC-9_AZD4547_30min_R2 1 VPAPFSPPPSKPR 13 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 VPAPFS(0.999)PPPS(0.001)KPR 89.23200000000001 0.0029296 34549000.0 92586.0 141860.0 155370.0 192580.0 168230.0 159270.0 134400.0 174210.0 126450.0 123710.0 True False 122026.42209156547 187713.47077650175 153309.69228304538 148183.65633134043 144874.16836117615 149310.82172212418 146361.33963270055 147289.84744754745 133133.88884720867 119378.95055439352 1.0221770381200133 1.5724168281322968 1.284227173811448 1.2412879795238476 1.213565437528001 1.2507298902254345 1.2260230044995482 1.233800823039039 1.1152208008944415 1.0 16.865188950839034 -8.662679783693262 0.4086615530973951 0.9780205193773702 1.3041510586980118 0.29569955513121704 0.1268138571144842 1.848535020020981 0.7521134724614019 0.20259873706359657 0.09421959241143552 2.174303757138301e-09 8.662679783693262 0.3261305393206416 VPAPFS(ph)PPPSKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VPAPFSPPPSKPR 13 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 VPAPFS(1)PPPSKPR;VPAPFS(0.999)PPPS(0.001)KPR 93.42399999999999 0.001948 51880000.0 83381.0 121863.0 126832.0 117297.0 168307.0 150845.0 174769.0 151397.0 150062.0 144458.0 True False 97495.75645018237 133960.75327549028 129856.15589303867 110725.22937200518 135328.451551909 142934.42265255403 158213.61510201334 147422.9891683809 152256.37286058723 170647.09187110123 0.5713297272233978 0.7850163270094161 0.7609631929217163 0.6488550619757517 0.7930311033611387 0.8376024524374547 0.9271392402134836 0.863905663741034 0.8922295199474862 1.0 17.380656303002567 -6.741220763835566 1.6158341507271095 0.911244250948148 0.7016439251423489 0.7036964663015648 0.06587593352054405 0.2246366972581118 1.2166432297580507 0.02792766885041046 0.025812392517537214 1.814593020726521e-07 6.741220763835566 -0.20960032580579913 VPAPFS(ph)PPPSKPR ddPTM_PC-9_Lapatinib_30min_R1 1 VPAPFSPPPSKPR 13 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 VPAPFS(1)PPPSKPR 73.834 0.009609999999999999 27778000.0 71137.0 74494.0 53380.0 49654.0 70678.0 78198.0 80409.0 80517.0 85433.0 66772.0 True False 70122.5733350719 74321.51371989786 48991.30245275879 53305.7208008883 66520.85899829438 74853.6538284413 84572.18457574143 84258.11376175993 75810.63589062676 78313.45123190251 0.8954090546644955 0.9490261577135237 0.6255796632903496 0.680671327369278 0.8494180495418623 0.9558211603621448 1.0799190081063532 1.0759085755556097 0.9680410542262479 1.0 16.25697250774087 -6.805270943444366 2.7002294601903465 1.035282221395319 0.786567826938744 0.5851961286183389 0.09306913891649386 0.2077735869981165 3.096729894318116 0.038852905908504785 0.03510864962039713 1.565773925429029e-07 6.805270943444366 -0.24871439445657495 VPAQANGTPT(ph)TK ddPTM_PC-9_AZD4547_30min_R2 1 VPAQANGTPTTK 12 0 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 VPAQANGT(0.11)PT(0.82)T(0.07)K 164.92 0.0019578 10528000.0 24089.0 29154.0 28529.0 28287.0 25343.0 28538.0 23468.0 31523.0 30075.0 21399.0 True False 31748.800917673507 38577.46036245691 28150.686819482537 21765.869179793463 21824.561902022702 26753.51434862799 25556.606536459934 26651.844676476907 31664.703100670602 20649.82752334867 1.537485041062705 1.8681734904970777 1.3632407722366047 1.0540460522095347 1.056888338527078 1.2955805232938582 1.2376184017790555 1.2906570113644669 1.533412473536036 1.0 14.333842111206339 -5.441123276265193 5.120693194589031 1.2190490294184924 1.6957576896491935 0.5853704189661858 0.16362017802757373 0.14924185262949505 6.699309595275448 0.04383407704188497 0.09290281784194952 3.621401888519717e-06 5.441123276265193 0.47670866023070113 VPAQANGTPT(ph)TK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VPAQANGTPTTK 12 0 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 VPAQANGT(0.058)PT(0.471)T(0.471)K 122.66 0.00095482 4843700.0 26018.0 23391.0 21692.0 20491.0 23664.0 19630.0 24277.0 18629.0 16510.0 13511.0 True False 30422.333521076132 25713.103894266427 22209.219547368102 19342.955702718344 19027.20907344537 18600.568243359976 21977.306809740727 18140.008489057054 16751.427516148655 15960.437346982839 1.9061090156672411 1.6110525880499906 1.3915169781714367 1.2119314328422797 1.1921483515639548 1.1654172024851328 1.3769865030606643 1.1365608657638846 1.0495594294798785 1.0 13.962212564297582 -1.522878745829433 0.4833215230939121 1.1275865683416302 24.18536229508701 0.8863752501116859 0.08887657857719905 32.680377167521016 0.3631186682783848 0.05369168911721308 758.4229280437338 0.029999999962069826 1.522878745829433 23.05777572674538 VPAQANGTPT(ph)TK ddPTM_PC-9_Lapatinib_30min_R1 2 VPAQANGTPTTK 12 0 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 VPAQANGT(0.211)PT(0.611)T(0.178)K;VPAQANGT(0.169)PT(0.416)T(0.416)K 158.86 0.00019391 20661300.0 46594.0 54474.0 59335.0 46533.0 58137.0 49827.0 53934.0 55984.0 61766.0 49190.0 True False 45929.561015706895 54347.868799872565 54456.70533972352 49955.19204953746 54717.49596173974 47696.015362410115 56726.43861891122 58585.22101964011 54809.2626551854 57692.425958445 0.7961107589545512 0.9420277947579901 0.9439142909148573 0.8658882205008929 0.9484346524299732 0.826729238197833 0.9832562537718631 1.0154750826709589 0.95002527185568 1.0 15.816094309348683 -7.372900526521626 8.456296223614363 0.9893184559220475 0.8941538117820363 0.4866087420760341 0.050024564795595465 0.2840746514883514 19.645716090866166 0.02026116437120381 0.013623848676450544 4.2374001095269015e-08 7.372900526521626 -0.09516464414001113 VPAS(ph)PLPGLER ddPTM_PC-9_AZD4547_30min_R2 4 VPASPLPGLER 11 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 VPAS(1)PLPGLER;VPAS(1)PLPGLER;VPAS(1)PLPGLER;VPAS(1)PLPGLER 105.65 0.0025321 337309000.0 49986.8 54797.1 69792.2 111711.0 84777.0 88129.0 82205.5 105925.0 79965.0 97492.9 True False 65881.56260996971 72509.19095930531 68866.70982658658 85957.75486774504 73007.17690753976 82618.27969830514 89521.63024684477 89556.72516435027 84191.786648217 94079.70324552934 0.7002739202740884 0.7707208723870093 0.7320039014882748 0.9136694940821866 0.7760141070705286 0.8781732599930491 0.9515509420051113 0.9519239758933444 0.8948985141725327 1.0 16.521595889055376 -4.422403095241324 0.22935328182935946 1.0088130393250714 0.3917643210621405 0.7589596390987416 0.04852432609090259 6.507237623743868 0.2631085250870591 0.07950857119579147 1.1740233283042805 3.780914919942561e-05 4.422403095241324 -0.617048718262931 VPAS(ph)PLPGLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 VPASPLPGLER 11 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 VPAS(1)PLPGLER;VPAS(1)PLPGLER;VPAS(1)PLPGLER;VPAS(1)PLPGLER;VPAS(1)PLPGLER;VPAS(1)PLPGLER 110.98 0.0018694000000000002 301560300.0 87631.0 100416.0 127345.0 130906.0 139112.0 131120.0 127312.0 148206.0 124092.0 113298.0 True False 102465.19750885619 110384.6368537755 130381.38775860169 123571.76122297824 111854.00222384749 124243.83637643197 115252.08570093977 144315.74953723748 125906.61074100039 133838.03053352545 0.765591043893831 0.8247628601059319 0.9741729405226275 0.9232933324734214 0.8357415435504999 0.9283148883852546 0.8611310644777455 1.0782865599706164 0.9407386692638285 1.0 17.03012859539477 -1.7257426180419213 0.21780642770283942 1.0022037854177583 1.4104984715034583e-13 0.4551221346545059 0.06515674867263574 47.19398537379662 0.6485432986926819 0.10906057689539804 16.27355650197026 0.018804309124738825 1.7257426180419213 -1.0022037854176173 VPAS(ph)PLPGLER ddPTM_PC-9_Lapatinib_30min_R1 4 VPASPLPGLER 11 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 VPAS(1)PLPGLER;VPAS(1)PLPGLER;VPAS(1)PLPGLER;VPAS(1)PLPGLER 110.15 0.0019722000000000003 288875000.0 133597.0 114713.0 132214.7 118811.7 111841.0 114055.2 107548.1 91211.0 135094.0 82425.9 True False 131691.88228131097 114447.38909644581 121344.5177295009 127549.50876221256 105262.73226786601 109177.32497165691 113116.41438110519 95448.99604212634 119878.29111711329 96673.10698939214 1.3622390588497524 1.1838596343966066 1.2552044876639368 1.3193897737889861 1.0888522728396057 1.1293453616178577 1.1700918477102153 0.9873376269224479 1.2400376366331893 1.0 16.5608269889092 -6.267850166922302 24.975684903095896 1.1066884479699284 1.2715102147957762 0.5300527435733281 0.08169038348530822 412.1611699956199 1605729.6339181203 0.023752988799832404 0.02757517318699585 5.39696787632198e-07 6.267850166922302 0.16482176682584782 VPASETS(ph)PGPPPMGPPPPSSK ddPTM_PC-9_AZD4547_30min_R2 2 VPASETSPGPPPMGPPPPSSK 21 0 Q9HD15 Q9HD15 SRA1 Steroid receptor RNA activator 1 1 VPAS(0.26)ET(0.307)S(0.433)PGPPPMGPPPPSSK;VPAS(0.007)ET(0.209)S(0.784)PGPPPMGPPPPSSK 104.84 0.0012644 0.0 38031.0 32790.0 49638.0 56234.0 56512.0 55129.0 45699.0 52947.0 45261.0 51065.0 True False 50124.066906058375 43388.72625660157 48979.76768710696 43270.12010663927 48666.284268125586 51681.774915043556 49766.122469306436 44765.257751020625 47653.404057837135 49277.22989297629 1.01718515864064 0.8805025434838001 0.9939634957866873 0.8780956275467658 0.9876018675120821 1.0487962701493088 1.00992126743715 0.90843697683991 0.967047136402231 1.0 15.588633537124622 VPCNVEGIS(ph)PELEK ddPTM_PC-9_AZD4547_30min_R2 2 VPCNVEGISPELEK 14 0 Q86VQ1;H7C2L5;H7C0B2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 VPCNVEGIS(1)PELEK;VPCNVEGIS(1)PELEK 101.75 0.0016312000000000002 34393000.0 31033.0 27563.0 35318.0 43744.0 45378.0 39522.0 36960.0 37158.0 32762.0 39843.0 True False 40900.84847350084 36472.20072615765 34849.66024362874 33659.49663806291 39078.047981296055 37050.68309224459 40249.36839899264 31416.084905895004 34493.73243505139 38448.10869726538 1.0637935092086834 0.9486084481641027 0.9064076602058562 0.875452597762161 1.0163841422991888 0.9636542432808878 1.0468491107302602 0.8171035187520023 0.8971503047562065 1.0 15.230625011801944 -7.762766577060004 24.999974812123785 0.892845208762368 0.9682290800511287 0.16614737780896538 0.06906906208475756 60.188140829625695 1133655.4886910368 0.03560752592182921 0.01857303472794216 1.7267657380763858e-08 7.762766577060004 0.07538387128876078 VPCNVEGIS(ph)PELEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VPCNVEGISPELEK 14 0 Q86VQ1;H7C2L5;H7C0B2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 VPCNVEGIS(1)PELEK;VPCNVEGIS(1)PELEK;VPCNVEGIS(1)PELEK 132.4 1.3362999999999999e-05 27652500.0 88610.0 105171.0 92897.0 115013.0 127499.0 111060.0 125676.0 96388.0 107140.0 98432.0 True False 103609.92287272468 115611.68182907514 95112.01679383416 108569.19448717688 102516.48620922957 105235.81809004385 113771.05946455366 93857.91713152801 108706.71981103403 116276.94241271674 0.8910616389014481 0.9942786543072287 0.8179783095451617 0.9337121550876204 0.8816579115518414 0.9050445935920536 0.9784490123650773 0.807192855126737 0.934894894511306 1.0 16.827205514800625 VPCNVEGIS(ph)PELEK ddPTM_PC-9_Lapatinib_30min_R1 2 VPCNVEGISPELEK 14 0 Q86VQ1;H7C2L5;H7C0B2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 VPCNVEGIS(1)PELEK;VPCNVEGIS(1)PELEK 118.31 0.00011750000000000001 30962000.0 62822.0 59631.0 66528.0 53465.0 65298.0 55840.0 50291.0 56399.0 53716.0 47961.0 True False 61926.14675985614 59492.92808321775 61058.324645506436 57396.99445401159 61457.300020807415 53451.85336939771 52894.82190424711 59019.50343467211 47665.93842544344 56250.994945984596 1.1008898032705225 1.057633347469609 1.0854621274546008 1.0203729642316095 1.0925548975590957 0.9502383632631781 0.9403357568170968 1.049217058139967 0.8473794725091527 1.0 15.77959099394034 -6.766175690658091 24.99984441592737 0.9594415311425987 1.0685671079159167 0.5449096974003438 0.0520193336295811 93.31549934835766 492547.3465604554 0.01696828573275459 0.015450708689025852 1.7132640788379378e-07 6.766175690658091 0.10912557677331802 VPDEEENEES(ph)DNEKETEK ddPTM_PC-9_AZD4547_30min_R2 2 VPDEEENEESDNEKETEK 18 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 VPDEEENEES(1)DNEKETEK;VPDEEENEES(0.999)DNEKET(0.001)EK 71.042 0.004442100000000001 7770700.0 21392.2 30385.1 17167.2 15509.3 12797.9 19902.0 27630.8 19918.9 21536.1 18819.8 True False 28194.474614598163 40206.48936198427 16939.55171115079 11933.870501296371 11021.132492834171 18657.52479383257 30089.887672047767 16840.891695786446 22674.45427918047 18160.924530301305 1.5524801376469568 2.213901021112674 0.9327472113485926 0.6571180052747225 0.606859660390391 1.0273444373772211 1.656847789981348 0.9273146676914824 1.2485297343397024 1.0 14.148550028286733 -5.2721101191279 24.925961419987143 1.001634580224504 1.88319057821889 0.5525037215321801 0.3153525042925629 460.2081149429187 1075008.993094105 0.08801023393266663 0.18623492108645914 5.34428833155712e-06 5.2721101191279 0.8815559979943861 VPDEEENEES(ph)DNEKETEK ddPTM_PC-9_Lapatinib_30min_R1 1 VPDEEENEESDNEKETEK 18 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 VPDEEENEES(1)DNEKETEK 121.35 3.2585e-05 24725000.0 13639.0 29058.0 20255.0 23827.0 19740.0 16695.0 30660.0 28465.0 16776.0 23081.0 True False 13444.50535891372 28990.717986318203 18589.712086561063 25579.317064541927 18578.932010333203 15980.993767945823 32247.42477946782 29787.58781659144 14886.510220888345 27070.52009650069 0.4966474715294311 1.0709331731703864 0.686714256700376 0.9449141343925813 0.686316034716113 0.5903467576898025 1.1912377251900796 1.1003699858888922 0.5499159294989929 1.0 14.724434985367353 -7.253039433845587 24.99189575851418 0.9687450797226052 0.7643860590688785 0.18248296724498192 0.21997405685303442 1147.8826183143278 3415238.8396885344 0.08337758593544006 0.06349177426046382 5.5841948806532723e-08 7.253039433845587 -0.2043590206537267 VPDS(ph)PENELK ddPTM_PC-9_AZD4547_30min_R2 4 VPDSPENELK 10 0 A0A0U1RR46;A0A0X1KG69;A0A087WUZ6;A0A2R8Y549;Q8NI35-4;Q8NI35-3;Q8NI35-2;Q8NI35 A0A0U1RR46 INADL InaD-like protein 1 VPDS(1)PENELK;VPDS(1)PENELK;VPDS(1)PENELK;VPDS(1)PENELK 132.86 0.00013238 79269000.0 195699.0 202406.0 220829.0 241266.0 211990.0 221404.0 247200.0 252696.0 204446.0 219172.0 True False 257927.21120792796 267829.78123494046 217900.6631728947 185645.851222542 182558.8477137589 207559.57287979647 269200.3211101457 213647.63957640494 215252.59817521868 211498.85499076478 1.2195206031691779 1.266341518712408 1.0302687604734762 0.8777629138022914 0.8631670735131424 0.9813744518326574 1.2728216477668426 1.0101597929962032 1.017748290810453 1.0 17.690290327363044 -5.29617808344151 5.99973230584318 1.0050412297223492 1.2434937318201134 0.44787070773758775 0.10504044290109642 0.1725874982589832 19.20261021625397 0.030783881641342725 0.06771627599586534 5.05617289967921e-06 5.29617808344151 0.23845250209776414 VPDS(ph)PENELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 VPDSPENELK 10 0 A0A0U1RR46;A0A0X1KG69;A0A087WUZ6;A0A2R8Y549;Q8NI35-4;Q8NI35-3;Q8NI35-2;Q8NI35 A0A0U1RR46 INADL InaD-like protein 1 VPDS(1)PENELK;VPDS(1)PENELK;VPDS(1)PENELK;VPDS(1)PENELK;VPDS(1)PENELK 142.76 0.00012749999999999998 43259600.0 192235.0 243597.0 208396.0 217816.0 247456.0 181631.0 241326.0 234192.0 180535.0 163429.0 True False 224776.58868568158 267779.7002835116 213364.95098623078 205612.47568899946 198968.77317775934 172105.95061689863 218465.85423106133 228044.70814693542 183174.98283633552 193057.383996748 1.1642993602848566 1.387047181205057 1.1051892787992241 1.0650329525467048 1.0306198553954866 0.8914756175282977 1.1316109734230178 1.1812275885328312 0.9488110687308446 1.0 17.558670209507902 -5.446414392881376 5.0456784380272355 1.043451135377931 1.2744354551678088 0.5078272857066638 0.09297455848686555 0.17334866909604557 7.888956017897586 0.02486198558642406 0.05263236474398654 3.5775491344340923e-06 5.446414392881376 0.23098431978987777 VPDS(ph)PENELK ddPTM_PC-9_Lapatinib_30min_R1 4 VPDSPENELK 10 0 A0A0U1RR46;A0A0X1KG69;A0A087WUZ6;A0A2R8Y549;Q8NI35-4;Q8NI35-3;Q8NI35-2;Q8NI35 A0A0U1RR46 INADL InaD-like protein 1 VPDS(1)PENELK;VPDS(1)PENELK;VPDS(1)PENELK;VPDS(1)PENELK 151.13 0.00015944 78238000.0 370940.0 484070.0 425517.0 438828.0 511190.0 420721.0 413684.0 455926.0 407751.0 385651.0 True False 365650.3275779343 482949.1656561731 390532.63480312045 471100.87500729394 481122.8092382084 402727.7435785523 435102.5333486425 477109.98639969324 361825.7885716166 452310.2615023434 0.8084059962810282 1.0677386890407106 0.8634175875337666 1.0415436374194513 1.063700849147584 0.8903794095692118 0.9619559191592391 1.054829012313313 0.7999504308609234 1.0 18.786953201006646 -4.737918877164921 24.715863955640657 0.9720741483920299 0.8084051953837647 0.23433907263238274 0.08843677341542291 2643.601100975845 2777789.44147925 0.020767707774951988 1.2121681994165334 1.828441722954576e-05 4.737918877164921 -0.16366895300826523 VPEASSEPFDT(ph)SSPQAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VPEASSEPFDTSSPQAGR 18 0 H0Y6F5;Q9H4I2 H0Y6F5 ZHX3 Zinc fingers and homeoboxes protein 3 1 VPEASSEPFDT(0.333)S(0.333)S(0.333)PQAGR 92.427 0.002783 15336000.0 11041.0 13537.0 16154.0 13163.0 18531.0 13383.0 12129.0 12949.0 13302.0 9334.4 True False 12910.023230309853 14880.863897083706 16539.17262438615 12425.519785021794 14899.983575896553 12681.171920574972 10980.053313644396 12609.102470599591 13496.516585088397 11026.652828930257 1.1708016413138773 1.349535904317336 1.4999268482447257 1.1268623378094735 1.3512698555996947 1.1500472643252002 0.9957739201543011 1.1435113326065292 1.2239903436225037 1.0 13.428707302849613 -6.881126745927561 5.028644537142648 1.0990810949849454 1.303382772277335 0.43194307943800325 0.11414386198091493 0.2130513046497199 8.498198144173742 0.04121041965874315 0.036326213869997966 1.31484104866385e-07 6.881126745927561 0.20430167729238957 VPEASSEPFDTS(ph)SPQAGR ddPTM_PC-9_AZD4547_30min_R2 1 VPEASSEPFDTSSPQAGR 18 0 H0Y6F5;Q9H4I2 H0Y6F5 ZHX3 Zinc fingers and homeoboxes protein 3 1 VPEASSEPFDT(0.002)S(0.499)S(0.499)PQAGR 202.84 3.5173e-16 19874000.0 7910.8 8976.9 17523.0 20941.0 21091.0 14465.0 14862.0 16995.0 14167.0 17850.0 True False 10426.26984513809 11878.507372152691 17290.633570675196 16113.375985224824 18162.878707160202 13560.501263329732 16184.689208491041 14368.813256248617 14915.838697496278 17225.076933117147 0.6052959812964558 0.6896054756838227 1.0038058835854609 0.935460320310387 1.0544439817415285 0.7872534512317994 0.9396004018637593 0.8341799175725572 0.8659374210874438 1.0 14.07222280606559 -5.129519703047194 4.612304383259655 0.9213296090318838 0.624320082741252 0.6764247184821857 0.07813704827092524 0.12515146771653524 4.042531435344945 0.020335745667443877 0.05970141874626642 7.4213052803981555e-06 5.129519703047194 -0.2970095262906318 VPEASSEPFDTS(ph)SPQAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VPEASSEPFDTSSPQAGR 18 0 H0Y6F5;Q9H4I2 H0Y6F5 ZHX3 Zinc fingers and homeoboxes protein 3 1 VPEASSEPFDT(0.029)S(0.486)S(0.486)PQAGR 103.39 0.00040510000000000003 14431000.0 11873.0 10731.0 11899.0 13095.0 19950.0 12628.0 12094.0 9952.5 11407.0 10202.0 True False 13882.8643975608 11796.302761291654 12182.717287208794 12361.329604562814 16040.940712273285 11965.765449676515 10948.368767022463 9691.257420545413 11573.805795076176 12051.541841012433 1.1519575321322137 0.9788210435570842 1.010884536429186 1.0257052390173136 1.3310280895083968 0.9928825379799942 0.9084620799111548 0.8041508338431212 0.9603589273274162 1.0 13.55693011223574 -6.9971726687512446 24.999896839815676 0.908886471744816 1.0917255349773338 0.4071256732888545 0.10317741975080665 90.74335288649641 802362.8966055709 0.03786819097870651 0.03321602230752592 1.0065314080091436e-07 6.9971726687512446 0.18283906323251786 VPEASSEPFDTS(ph)SPQAGR ddPTM_PC-9_Lapatinib_30min_R1 1 VPEASSEPFDTSSPQAGR 18 0 H0Y6F5;Q9H4I2 H0Y6F5 ZHX3 Zinc fingers and homeoboxes protein 3 1 VPEASSEPFDT(0.004)S(0.973)S(0.022)PQAGR 185.96 1.2581999999999999e-10 19727000.0 15994.0 20609.0 19626.0 15724.0 18801.0 16075.0 17519.0 13996.0 19561.0 12250.0 True False 15765.922627059628 20561.281126713176 18012.426038550842 16880.395413726324 17695.162144188176 15387.509722655237 18426.048098874664 14646.305254910027 17357.834193538216 14367.396177901017 1.0973402857303909 1.4311069919780723 1.2537014929856511 1.1749098587321367 1.2316192805628698 1.071001977819982 1.2824904297701762 1.019412639113969 1.208140569008384 1.0 13.810511003515288 -7.922422309415199 0.21260311902810727 0.9531544299248222 1.3287302679040838 0.28454406671186294 0.10675206812262733 2.985603991616137 0.666881650433108 0.4378260265359974 0.44675913045592236 1.1955773824052882e-08 7.922422309415199 0.37557583797926153 VPEASSEPFDTSS(ph)PQAGR ddPTM_PC-9_AZD4547_30min_R2 1 VPEASSEPFDTSSPQAGR 18 0 H0Y6F5;Q9H4I2 H0Y6F5 ZHX3 Zinc fingers and homeoboxes protein 3 1 VPEASSEPFDT(0.292)S(0.292)S(0.416)PQAGR 157.83 1.109e-05 20763000.0 11906.0 11217.0 14195.0 17385.0 18235.0 17231.0 16452.0 19302.0 16597.0 17177.0 True False 15691.860339815716 14842.67588960964 14006.765025151772 13377.156845572492 15703.385009011721 16153.542846072221 17916.196128252897 16319.319415834707 17474.283536552957 16575.638458271893 0.946682106955878 0.895451232661422 0.8450211471740835 0.8070371997584664 0.9473773844997878 0.9745351822638826 1.080875175538835 0.9845364000257093 1.0542148093144856 1.0 14.016776820496244 -6.694758163738164 2.394617003247409 1.0267602317938969 0.8739170536491079 0.7055237869035027 0.04428838927423414 0.16141212415665393 1.8937875290584736 0.016949691344930268 0.016328539406859 2.0194906010937872e-07 6.694758163738164 -0.15284317814478898 VPEASSEPFDTSS(ph)PQAGR ddPTM_PC-9_Lapatinib_30min_R1 1 VPEASSEPFDTSSPQAGR 18 0 H0Y6F5;Q9H4I2 H0Y6F5 ZHX3 Zinc fingers and homeoboxes protein 3 1 VPEASSEPFDTS(0.397)S(0.603)PQAGR 206.63 3.2391e-20 18110000.0 21429.0 23678.0 23912.0 16518.0 22984.0 20743.0 16992.0 17166.0 16180.0 15711.0 True False 21123.418530402683 23623.175045771994 21946.047662989284 17732.788822432674 21632.12630828261 19855.87024429471 17871.762617505454 17963.59502756399 14357.638017046578 18426.62541640841 1.1463530653633873 1.2820130931155846 1.1909965697488443 0.9623459760918626 1.173960278642219 1.077564111473911 0.969887986195841 0.9748716664945009 0.7791789159756561 1.0 14.1695042649085 -6.878675166360341 0.6449318328944004 0.8945745491877719 1.204310340556551 0.5694335624782094 0.09148476122068072 0.5688932230170408 0.5099545046113314 0.07500679148748927 0.0718784535047159 1.322284276317442e-07 6.878675166360341 0.30973579136877905 VPEEAAQDRPMS(ph)PGDCPPETTETPK ddPTM_PC-9_AZD4547_30min_R2 2 VPEEAAQDRPMSPGDCPPETTETPK 25 1 P13994 P13994 CCDC130 Coiled-coil domain-containing protein 130 1 VPEEAAQDRPMS(1)PGDCPPETTETPK;VPEEAAQDRPMS(0.998)PGDCPPET(0.001)T(0.001)ETPK 75.225 0.00025909 13115400.0 21001.0 20632.3 23887.0 38764.0 34827.0 30246.0 23574.0 32920.0 23909.0 29959.0 True False 27678.881152063645 27301.287488383055 23570.242772511476 29827.558697829867 29991.872207779066 28354.71283862227 25672.040331110726 27832.97042634329 25172.78092880911 28910.144528809884 0.9574106806861776 0.9443497406654764 0.8152931490544081 1.0317332958368903 1.0374168893514595 0.9807876543254874 0.8879941885287953 0.9627406185606179 0.8707248386020218 1.0 14.819288200764138 -5.780760609279779 24.992467644010734 0.9659637988701435 0.9095509412127929 0.17124537654376892 0.06193186582308893 478.87388051332573 619432.9551717273 0.018470939306627403 0.027442193966822966 1.656682904447035e-06 5.780760609279779 -0.0564128576573506 VPEEAAQDRPMS(ph)PGDCPPETTETPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VPEEAAQDRPMSPGDCPPETTETPK 25 1 P13994 P13994 CCDC130 Coiled-coil domain-containing protein 130 1 VPEEAAQDRPMS(1)PGDCPPETTETPK 57.692 0.015408000000000002 0.0 6464.1 6616.7 7519.2 8000.5 7584.1 9036.2 10230.0 8253.0 5870.7 4676.9 True False 7558.344458205407 7273.562247753098 7698.4862447248 7552.25792297096 6098.050047917383 8562.325764679039 9260.940341213804 8036.367494776309 5956.547881226767 5524.784947679971 1.3680793967155935 1.3165330988688515 1.3934454132839384 1.3669777184978735 1.1037624279797793 1.5498025435858143 1.6762535427017409 1.4546027711270517 1.0781501791717896 1.0 12.431702593337397 -8.334703241050546 4.831288122818103 1.0148116613324878 1.4030533185399818 0.5167024902371724 0.14149597386279567 0.1973239649367617 8.285514506631378 0.14742805751694668 0.03907162522198898 4.6269708020999134e-09 8.334703241050546 0.38824165720749404 VPEEAAQDRPMS(ph)PGDCPPETTETPK ddPTM_PC-9_Lapatinib_30min_R1 1 VPEEAAQDRPMSPGDCPPETTETPK 25 1 P13994 P13994 CCDC130 Coiled-coil domain-containing protein 130 1 VPEEAAQDRPMS(1)PGDCPPETTETPK 61.611999999999995 0.0037527000000000003 7491700.0 5918.5 9346.7 12636.0 9734.0 13100.0 12781.0 11184.0 11695.0 14245.0 9224.2 True False 5834.101104680028 9325.058290409543 11597.116856370552 10449.870831672104 12329.48375559094 12234.386423966185 11763.052796267715 12238.392394696535 12640.57809349991 10818.590679526096 0.5392662757563158 0.8619476017386419 1.0719618848615649 0.9659179408135123 1.1396571069949222 1.130866929564074 1.0872999214702697 1.131237215384937 1.1684126396816064 1.0 13.401224953382837 -4.530411902863419 1.0902675669337123 1.1054352355934571 9.675879006211712e-19 0.8953176954420323 0.05846970082705935 0.7696651186341351 0.5276415156408795 0.017908753736611396 1.118390120669229 2.948411504623625e-05 4.530411902863419 -1.1054352355934571 VPEPEGQT(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 1 VPEPEGQTSPK 11 0 Q504Q3-2;Q504Q3-3;Q504Q3 Q504Q3-2 PAN2 PAB-dependent poly(A)-specific ribonuclease subunit PAN2 1 VPEPEGQT(0.807)S(0.193)PK 98.40700000000001 0.008415100000000002 0.0 31200.0 31913.0 28569.0 36387.0 31820.0 29763.0 29692.0 26289.0 29278.0 29339.0 True False 41120.95099968502 42228.25315727133 28190.156393347013 27998.53932354594 27402.34225318087 27901.91490497635 32334.530478974273 22226.63911112209 30825.575307778367 28311.85054009658 1.4524289375379253 1.4915398446832602 0.9957016533914935 0.9889335663132682 0.9678753500896162 0.9855207050298722 1.1420846699222498 0.7850648646100923 1.0887870174406908 1.0 14.789118430374417 -5.263248058949654 24.80084641136249 0.9904065094660292 1.4719844302666985 0.8271823657890158 0.0873320001302698 46.22479043687326 633852.3433682128 0.0214314558418138 0.04865200451537371 5.454462258488437e-06 5.263248058949654 0.4815779208006693 VPEPEGQT(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VPEPEGQTSPK 11 0 Q504Q3-2;Q504Q3-3;Q504Q3 Q504Q3-2 PAN2 PAB-dependent poly(A)-specific ribonuclease subunit PAN2 1 VPEPEGQT(0.915)S(0.085)PK 97.95700000000001 0.0087246 0.0 24639.0 28942.0 24072.0 35263.0 35558.0 29781.0 34204.0 32542.0 28490.0 26299.0 True False 28809.896057567654 31815.170488985485 24645.967773568387 33287.32843418849 28590.665155238778 28219.231933545772 30963.94950448453 31687.8069810991 28906.612352215332 31066.800517230535 0.9273531737389199 1.0240890583933766 0.7933217249036968 1.071475912549359 0.9202964154413512 0.9083404619633934 0.9966893593471604 1.019989392326517 0.9304663457758677 1.0 14.923086049538172 -7.2852826027087385 24.01587745987315 0.9884520657465483 0.9429006032409902 0.08828030958247435 0.07211258412605881 1300.7111281588693 1310121.8396425634 0.028909829066525825 0.01950415440840738 5.184625568504274e-08 7.2852826027087385 -0.04555146250555808 VPEPEGQTS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 VPEPEGQTSPK 11 0 Q504Q3-2;Q504Q3-3;Q504Q3 Q504Q3-2 PAN2 PAB-dependent poly(A)-specific ribonuclease subunit PAN2 1 VPEPEGQT(0.081)S(0.919)PK;VPEPEGQT(0.213)S(0.787)PK 122.46 0.00066713 20201300.0 88474.0 78881.0 61444.0 72576.0 75348.0 67609.0 70092.0 69248.0 64835.0 63766.0 True False 87212.34453585545 78698.35589093405 56392.311500698954 77913.48114643885 70916.17877986758 64717.52067427671 73721.02079720995 72465.51488225276 57532.59955718263 74787.86813714584 1.1661295703191543 1.0522877286275518 0.7540302044348537 1.0417930486206837 0.94823105065412 0.8653478470010384 0.9857350213810145 0.9689474601597902 0.7692771700843173 1.0 16.19051663899515 -5.018053087527826 10.038566079294052 0.9205112683239988 1.1381382500035915 0.43933554107168393 0.09100089142687615 0.29339088282829917 164.42780564155277 0.022006968079956574 0.06448966061952392 9.592833629411958e-06 5.018053087527826 0.2176269816795927 VPEVVQTS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VPEVVQTSSPR 11 0 A0A590UJ23;K7EKN5;A0A590UJ36;A6NDB9 A0A590UJ23 PALM3 Paralemmin-3 1 VPEVVQT(0.166)S(0.651)S(0.183)PR;VPEVVQT(0.098)S(0.719)S(0.184)PR 99.161 0.0046767 6051300.0 24006.0 22255.1 29494.0 20354.5 44460.0 19567.5 20216.8 9499.7 17146.7 12183.5 True False 28069.74165988752 24464.439249168026 30197.24881661788 19214.103355179373 35748.382158780456 18541.34585338495 18301.718347043123 9250.342940764152 17397.43804913061 14392.27210546707 1.9503342803826582 1.6998316228245107 2.0981571634646285 1.3350291888853794 2.483859525224028 1.2882848321316693 1.2716350978446973 0.6427298534225394 1.2088041361114896 1.0 13.813006747620085 -6.957537451981949 8.610993952968352 1.040044974033837 1.881890856846366 0.6424040482797391 0.31429402364423514 0.17388806828676268 32.21796040855135 0.10617085264469868 0.09339600973965263 1.1027131357652867e-07 6.957537451981949 0.8418458828125288 VPEVVQTS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 VPEVVQTSSPR 11 0 A0A590UJ23;K7EKN5;A0A590UJ36;A6NDB9 A0A590UJ23 PALM3 Paralemmin-3 1 VPEVVQT(0.035)S(0.749)S(0.217)PR 85.271 0.033109 0.0 25463.0 57320.0 29815.0 17108.0 25625.0 20381.0 19947.0 19970.0 26085.0 10838.0 True False 25099.8929506577 57187.27906173031 27363.725789228236 18366.17939061499 24117.787880688367 19509.3521404315 20979.75805857943 20897.879104069252 23147.032612772586 12711.333859272765 1.9746073251272234 4.498920388281115 2.152702941498679 1.4448664155899802 1.8973451683117213 1.5347997587365438 1.650476518896162 1.6440351056332692 1.820975899857048 1.0 13.633827806524023 -5.497579271880667 12.74333771461735 1.6269002147850422 3.2593742525122953 0.5373798636997307 0.6110140061876987 1.137066586094713 570.6607671731118 0.14534861329693904 0.2941516682298467 3.1799531976981343e-06 5.497579271880667 1.632474037727253 VPEVVQTSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VPEVVQTSSPR 11 0 A0A590UJ23;K7EKN5;A0A590UJ36;A6NDB9 A0A590UJ23 PALM3 Paralemmin-3 1 VPEVVQT(0.089)S(0.309)S(0.601)PR 92.15100000000001 0.0078033 5992000.0 14686.0 22488.0 19099.0 12889.0 23058.0 11662.0 13739.0 9081.5 13243.0 9883.4 True False 17172.049738278274 24720.46002198553 19554.39259336085 12166.871116701795 18539.950423237966 11050.424190222322 12437.5424582538 8843.120247644623 13436.65382170543 11675.182183048653 1.4708164265916632 2.1173511157605303 1.6748683049890327 1.0421140266545075 1.587979539210648 0.946488373112205 1.0652975057050524 0.7574288871041398 1.150873160781532 1.0 13.511157441906668 -6.036835870428396 0.8675580463380329 0.9666683262101885 1.8545772361801312 0.588017258855311 0.25435706991422513 0.44842635813796117 0.6871591337327175 0.1184991414616091 0.26165678482707594 9.186797204439162e-07 6.036835870428396 0.8879089099699427 VPFS(ph)PGPAPPPHMGELDQER ddPTM_PC-9_AZD4547_30min_R2 2 VPFSPGPAPPPHMGELDQER 20 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 VPFS(1)PGPAPPPHMGELDQER;VPFS(1)PGPAPPPHMGELDQER 98.07700000000001 0.00029009 33381000.0 46632.0 30123.0 52832.0 55443.0 44665.0 43588.0 39503.0 50748.0 38777.0 33811.0 True False 61460.005994144645 39859.67066262915 52131.41316018444 42661.47293581108 38464.03572402023 40862.435469479184 43018.69047254888 42906.06267302763 40826.673055185514 32627.287181267464 1.8836995442707574 1.2216667123190696 1.597785708341545 1.3075396890583233 1.1788916286642384 1.252400643745209 1.3184881180451773 1.3150361669560315 1.2513045546313646 1.0 14.99379141807226 -1.9249889724182512 0.9809147524275522 1.26456627045353 199.99999998619813 0.5918537470814578 0.14773715886958963 429.7193175850049 1.5876540128309642 0.04544998248416233 190567.58179888004 0.01188532406203769 1.9249889724182512 198.7354337157446 VPFS(ph)PGPAPPPHMGELDQER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VPFSPGPAPPPHMGELDQER 20 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 VPFS(1)PGPAPPPHMGELDQER;VPFS(1)PGPAPPPHMGELDQER 89.344 0.00048173 17828200.0 28153.0 27436.0 41460.0 38910.0 35095.0 43267.0 45640.0 43293.0 36681.0 30968.0 True False 32918.74685290401 30159.664761792726 42448.563637925574 36729.99884792202 28218.386681565476 40998.00235279963 41316.64879501448 42156.60462272518 37217.39023136578 36582.25325744689 0.8998556382308923 0.8244343110727673 1.1603594600691935 1.0040387230779737 0.7713681954738855 1.1207074114401043 1.1294178219217217 1.1523785679916678 1.017361887728706 1.0 15.15885631913111 -6.827375297021101 24.99988233762352 1.0963377205941833 0.9427164870514436 0.3258644853938375 0.10801115512792368 71.78682939142757 27217.213731223062 0.03925948395733228 0.03462362021070296 1.4880745973198627e-07 6.827375297021101 -0.1536212335427397 VPFS(ph)PGPAPPPHMGELDQER ddPTM_PC-9_Lapatinib_30min_R1 2 VPFSPGPAPPPHMGELDQER 20 0 Q6Y7W6;I1E4Y6;Q6Y7W6-3;Q6Y7W6-5;Q6Y7W6-4;E7ESB6;C9JHW1 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 VPFS(1)PGPAPPPHMGELDQER;VPFS(1)PGPAPPPHMGELDQER 95.554 0.00036699 15077500.0 27176.0 24763.7 29120.0 26800.0 32005.0 31716.0 26367.0 28262.0 37444.0 26363.0 True False 26788.46525653195 24706.361174127203 26725.866006450648 28770.9614021792 30122.52882425098 30359.58061360706 27732.154245278176 29575.155695503505 33226.66241719977 30919.80942351059 0.8663851995207552 0.7990463600768882 0.8643606317356218 0.9305025463805912 0.9742145694257295 0.9818812334115635 0.8969057300913179 0.9565115777529778 1.0746076071198263 1.0 14.916243806684024 -5.817745255138797 2.1480076086225246 0.9743268141646625 0.8312542679362022 0.66010018807726 0.04423317494153333 0.19710162954727795 1.856559631038311 0.01388590809284595 0.025316811436897957 1.521439701548034e-06 5.817745255138797 -0.14307254622846033 VPGEDGTLPPT(ph)QGSPLR ddPTM_PC-9_AZD4547_30min_R2 2 VPGEDGTLPPTQGSPLR 17 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 VPGEDGT(0.003)LPPT(0.661)QGS(0.337)PLR;VPGEDGT(0.001)LPPT(0.5)QGS(0.5)PLR 134.76 8.217700000000001e-05 50540000.0 23378.7 36615.7 36256.8 37379.0 32417.0 40042.2 31638.1 35078.0 29876.6 36756.0 True False 30812.6402928313 48451.00896596053 35776.01114222774 28761.849049793163 27916.459108150964 37538.35490400978 34453.82960887903 29657.501112249996 31455.816081712226 35469.183627655686 0.8687158017588645 1.3660029358043295 1.0086505378244122 0.8108968436298392 0.7870623525257631 1.0583371553762162 0.9713736287410637 0.8361483992297398 0.8868491705906026 1.0 15.114278504581879 -5.51948557578893 24.93190237798525 0.9047873484584799 1.1348512164742417 0.2722473280706449 0.13749312215372472 140.04853343838664 1029029.4977406962 0.035804437196653646 0.06373081166184949 3.02353098929801e-06 5.51948557578893 0.23006386801576184 VPGEDGTLPPT(ph)QGSPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VPGEDGTLPPTQGSPLR 17 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 VPGEDGTLPPT(0.5)QGS(0.5)PLR 86.411 0.012534 0.0 2672.6 2744.2 1405.2 3626.9 3213.1 3051.8 3214.4 2685.5 2540.7 2635.2 True False 3125.018393743873 3016.6260402140124 1438.7052972506756 3423.696551568451 2583.516120431344 2891.7582356131425 2909.908761759301 2615.008470522451 2577.8529309678315 3112.9408997682795 1.0038797697625716 0.9690598496227678 0.4621691652924634 1.0998270323163872 0.8299277768568158 0.9289473615860805 0.9347780299895536 0.8400443679213783 0.8281085359377434 1.0 11.604062471677791 VPGEDGTLPPTQGS(ph)PLR ddPTM_PC-9_AZD4547_30min_R2 2 VPGEDGTLPPTQGSPLR 17 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 VPGEDGTLPPT(0.002)QGS(0.998)PLR;VPGEDGTLPPT(0.011)QGS(0.989)PLR 243.37 3.7578000000000004e-47 36451000.0 27258.0 24857.0 31851.0 44957.0 46120.0 37182.0 34684.0 43747.0 35885.0 36634.0 True False 35925.476998378675 32891.53914487178 31428.634928926316 34592.85822872605 39717.03408914839 34857.00366215875 37770.808808188885 36986.90635605226 37781.80783932053 35351.45481052177 1.0162375831753905 0.9304154332874064 0.8890337073079128 0.9785412909917943 1.1234907955563762 0.9860132729752368 1.0684371834379793 1.046262637684821 1.0687483172001002 1.0 15.109481966712494 -6.011962226305559 24.008194155414717 1.0491637281039492 0.942087538073328 0.5164929079163649 0.04598062615303589 251.77662025261623 505318.6118138349 0.012821632720592058 0.017527042991003324 9.728318342335385e-07 6.011962226305559 -0.10707619003062119 VPGEDGTLPPTQGS(ph)PLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VPGEDGTLPPTQGSPLR 17 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 VPGEDGTLPPT(0.028)QGS(0.972)PLR;VPGEDGTLPPT(0.03)QGS(0.97)PLR;VPGEDGTLPPT(0.379)QGS(0.621)PLR;VPGEDGTLPPT(0.021)QGS(0.979)PLR 195.17 4.146e-12 63894000.0 92167.0 96969.0 93100.0 91685.0 105128.0 81799.0 92125.0 91775.0 99774.0 72821.0 True False 107769.05271877263 106595.44147420485 95319.85708371614 86548.18669678063 84528.9230676625 77509.31644109025 83398.25307275874 89366.00349365023 101233.00599613656 86022.87084928132 1.2527953514547578 1.2391523373007194 1.1080757494216145 1.0061066997917298 0.9826331327137835 0.9010315009934107 0.9694893026632289 1.0388633000894185 1.1768150143873317 1.0 16.392432658831417 -5.443154839636509 2.234850990983786 1.0042450117590924 1.2549394364177384 0.6673968586871855 0.0660236442788957 0.19815696353152526 1.9052888068646974 0.02051877169498138 0.05547651152371473 3.604501083139285e-06 5.443154839636509 0.250694424658646 VPGEDGTLPPTQGS(ph)PLR ddPTM_PC-9_Lapatinib_30min_R1 4 VPGEDGTLPPTQGSPLR 17 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 VPGEDGTLPPT(0.141)QGS(0.859)PLR;VPGEDGTLPPT(0.006)QGS(0.994)PLR;VPGEDGTLPPT(0.045)QGS(0.955)PLR;VPGEDGT(0.006)LPPT(0.252)QGS(0.742)PLR 163.0 2.7193000000000002e-05 76235000.0 113871.0 136777.0 139241.0 120311.0 144393.0 131552.0 120202.0 115164.0 140879.0 102857.0 True False 112247.17865861593 136460.30126005373 127793.14246580334 129159.07228573036 135900.0876275604 125925.82762268986 126425.47140709698 120514.9398668518 125011.72349836247 120635.69540166279 0.9304640577971813 1.1311768113550646 1.0593310880358378 1.0706538546131685 1.1265329650156533 1.0438521301959034 1.0479938875981676 0.99899900660075 1.0362747367777794 1.0 16.88029732992765 -7.471034902485959 2.2866790016766783 1.013440205270804 1.0673993953772767 0.13455341447026348 0.05285618290750066 0.5698980479353656 5.875676259314554 0.02779447996293686 0.015403116917508234 3.3803766839802576e-08 7.471034902485959 0.053959190106472654 VPGGS(ph)PLGVSLVYSDKK ddPTM_PC-9_AZD4547_30min_R2 2 VPGGSPLGVSLVYSDKK 17 1 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 VPGGS(0.993)PLGVS(0.007)LVYSDKK;VPGGS(1)PLGVSLVYSDKK 104.81 0.00035006 23662200.0 63253.0 59686.0 76651.0 112479.0 88846.0 90170.0 69416.0 88352.0 75536.0 89273.0 True False 83366.13825586803 78978.33227665498 75634.5576571263 86548.70433322678 76511.2664935924 84531.65564565803 75593.88952338939 74699.22852698322 79528.67875019957 86147.57944258624 0.96771306629025 0.9167794706210026 0.8779649776176656 1.0046562525985756 0.8881418025747776 0.9812423772393378 0.8774929024415544 0.8671076890415376 0.923167885444792 1.0 16.39452264001317 -7.282842425674444 24.979914776861882 0.90586776587604 0.9362289321395114 0.025496101067730814 0.05025211552856311 2304.7240665859276 2689879.562565256 0.020051291326289543 0.013529536441214261 5.213838496027891e-08 7.282842425674444 0.030361166263471406 VPGGS(ph)PLGVSLVYSDKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VPGGSPLGVSLVYSDKK 17 1 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 VPGGS(1)PLGVSLVYSDKK;VPGGS(1)PLGVSLVYSDKK 95.755 0.00074223 15508300.0 60296.0 52975.0 66678.0 75632.0 92263.0 78680.0 69467.0 71303.0 69006.0 54313.0 True False 70502.92189971588 58234.007900421755 68267.85639772304 71394.58424225237 74184.72746548719 74553.88229177601 62886.58286247301 69431.37180177338 70015.08220347395 64159.51695852859 1.098869275236089 0.9076441136248429 1.064033204019444 1.1127668602679845 1.1562544573619327 1.162008160690582 0.9801598553667669 1.082167932259409 1.0912657314538432 1.0 15.969375659681456 -5.505471358740433 24.027090429475226 1.0888946036045113 0.9989021663585991 0.16770375190431097 0.06967829517978492 650.7111069941602 898161.492886514 0.018225219578970824 0.03660562769659557 3.1226883374101703e-06 5.505471358740433 -0.08999243724591222 VPGGS(ph)PLGVSLVYSDKK ddPTM_PC-9_Lapatinib_30min_R1 1 VPGGSPLGVSLVYSDKK 17 1 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 VPGGS(1)PLGVSLVYSDKK 107.82 0.00025888 7152900.0 43514.0 33756.0 46220.0 29732.0 34639.0 38878.0 35576.0 33290.0 37052.0 27160.0 True False 42893.482380509726 33677.84005596245 42419.970014359526 31918.590463044482 32601.60212289425 37215.27856904449 37417.95120529511 34836.77493111992 32878.81358514279 31854.569811574846 1.346540940098451 1.0572373212123898 1.331676122618538 1.0020097791886167 1.023451338873456 1.1682869613113327 1.1746493965113516 1.0936193813693083 1.032153746844692 1.0 14.959212733870087 -1.5228787452973476 0.7091861228054263 1.0897933196533598 30.21503248189186 0.33996298489096866 0.0999494080107152 386.6965443027627 1.9778468359210413 0.03861277354095064 17885.953285242984 0.02999999999882499 1.5228787452973476 29.1252391622385 VPGGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 VPGGSPR 7 0 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 VPGGS(1)PR 72.87899999999999 0.037712999999999997 7923400.0 29918.0 28114.0 33372.0 34068.0 22621.0 26794.0 18678.0 29895.0 21327.0 22886.0 True False 29491.36383371074 28048.903760319008 30628.2829796453 36573.47436751643 21290.477254597135 25648.083079864642 19645.055447844115 31284.03083706311 18924.928676733784 26841.814606321885 1.0987097655746725 1.044970475048018 1.1410660355440951 1.3625559562170029 0.7931832317172298 0.9555271674450769 0.7318825398345922 1.1654961222217435 0.7050539970675647 1.0 14.71219458592544 -6.277097145441025 24.99803625384674 0.8953167486721763 1.1519959575889698 0.4426450116267787 0.14821321833520051 780.1608152556944 1245544.529199798 0.04422561942470366 0.0503211172106856 5.283270593779941e-07 6.277097145441025 0.2566792089167935 VPGS(ph)SGHLHK ddPTM_PC-9_AZD4547_30min_R2 1 VPGSSGHLHK 10 0 Q9UEW8-2;Q9UEW8 Q9UEW8-2 STK39 STE20/SPS1-related proline-alanine-rich protein kinase 1 VPGS(0.5)S(0.5)GHLHK 84.479 0.007093899999999999 5560600.0 12695.0 13099.0 24073.0 34454.0 31415.0 37557.0 25770.0 41778.0 33231.0 29080.0 True False 16731.7459275962 17332.995585093755 23753.776290981215 26511.162608993665 27053.569512371985 35208.554852877605 28063.48007689504 35322.17006293347 34987.52281756891 28061.918051263106 0.5962438453790253 0.6176696672490487 0.8464772881022659 0.9447380810022842 0.9640670129158996 1.2546738533181918 1.0000556635376485 1.2587225861898477 1.2467972700103467 1.0 14.776326001068721 -5.619595875354069 0.7656100019951467 1.168112151886889 0.49249182478547743 0.811184306956759 0.09932533824255958 0.4229113557343892 0.3950533557442007 0.0451779252851468 0.20307985718149257 2.4010661472223706e-06 5.619595875354069 -0.6756203271014116 VPGS(ph)SGHLHK ddPTM_PC-9_Lapatinib_30min_R1 1 VPGSSGHLHK 10 0 Q9UEW8-2;Q9UEW8 Q9UEW8-2 STK39 STE20/SPS1-related proline-alanine-rich protein kinase 1 VPGS(0.618)S(0.382)GHLHK 60.255 0.039106999999999996 5357600.0 11920.0 14052.0 25909.0 18009.0 23528.0 18601.0 16110.0 18110.0 23875.0 16188.0 True False 11750.018614139717 14019.46345735231 23778.862031632212 19333.441936262872 22144.12929782776 17805.478591048828 16944.096973164596 18951.456713805404 21185.946085104268 18986.07423084587 0.6188756280669103 0.7384077027664563 1.2524370094898136 1.0182959205359394 1.1663353376050292 0.9378178118634458 0.8924486846067546 0.9981766890501133 1.1158676526548263 1.0 14.212654008407418 -5.087189652395359 5.9007594847385105 1.0406439388749806 0.64597398241501 0.6824012897839568 0.10197860133167456 0.11704484722343521 6.190388796425766 0.02701928481548639 0.075523615618796 8.181074501381462e-06 5.087189652395359 -0.3946699564599706 VPGSS(ph)GR ddPTM_PC-9_Lapatinib_30min_R1 1 VPGSSGR 7 0 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 VPGS(0.226)S(0.774)GR 70.816 0.043012 1407400.0 9650.1 16987.0 11794.0 16394.0 15086.0 8805.2 17055.0 13874.0 15927.0 17380.0 True False 9512.4878043884 16947.66764517817 10824.342846156558 17599.669448780813 14198.671140217159 8428.622121923723 17938.024449244094 14518.636689527119 14133.133541254701 20384.109842605692 0.4666619184177445 0.8314156358083948 0.5310186674687232 0.8634014232004872 0.6965558589436127 0.41348983041225096 0.8800003820500941 0.71225267140099 0.693340727183212 1.0 14.315157336439755 -14.522878745260416 0.2110821919174649 2.5464312384985504 0.6375299270596585 0.3061308402074038 0.15152352890130188 186.51746070999064 1.8552084620829787 121.94226999755097 0.307751335828287 3.0000000001376162e-15 14.522878745260416 -1.9089013114388917 VPKPEPIPEPKEPS(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 2 VPKPEPIPEPKEPSPEK 17 2 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 VPKPEPIPEPKEPS(1)PEK;VPKPEPIPEPKEPS(1)PEK 91.06700000000001 0.006407600000000001 168936000.0 81159.0 74470.0 64200.0 49123.0 62856.0 83207.0 77118.0 59004.0 70391.0 75735.0 True False 106965.87378793088 98540.97115977795 63348.66605246519 37798.45129278444 54129.529373536665 78004.05313638969 83981.35260263823 49886.287577034 74111.72455392539 73083.54070193988 1.463610995862597 1.3483332938350967 0.8667979882203997 0.5171951294333108 0.7406528043611861 1.0673272311000552 1.14911444897208 0.6825926480558413 1.014068610279554 1.0 16.15725890992139 -5.222544397282972 4.505740928807981 0.865590658186177 1.427164064713647 0.5711208180711114 0.18288049113579208 0.15132427503003684 7.2496075652868175 0.05108340926391307 0.14018206109680337 5.990396965383031e-06 5.222544397282972 0.56157340652747 VPKPEPIPEPKEPS(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 VPKPEPIPEPKEPSPEK 17 2 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 VPKPEPIPEPKEPS(1)PEK;VPKPEPIPEPKEPS(1)PEK;VPKPEPIPEPKEPS(1)PEK;VPKPEPIPEPKEPS(1)PEK;VPKPEPIPEPKEPS(1)PEK 109.5 0.0012772999999999999 309022500.0 454051.0 420556.0 271114.0 507385.0 434459.0 320209.0 467876.0 408702.0 322567.0 351739.0 True False 530912.8663839696 462306.02032222395 277578.3859655713 478957.8634143638 349329.87774002674 303416.6763442719 423555.39815109863 397974.005555563 327283.93213819066 415506.4963356087 1.2777486539106864 1.1126324724146186 0.6680482457279524 1.1527084838344015 0.8407326499604703 0.7302332912244031 1.0193713019807729 0.957804532697644 0.7876746453413817 1.0 18.664511507769134 -5.028881927873696 7.310536134003853 0.8979993392641175 1.2394231992763818 0.44977539182394677 0.13841442266430917 0.14756564613665715 31.4871280769466 0.03384237433906966 0.09811049433100139 9.356600185067718e-06 5.028881927873696 0.3414238600122643 VPKPEPIPEPKEPS(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 2 VPKPEPIPEPKEPSPEK 17 2 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 VPKPEPIPEPKEPS(1)PEK;VPKPEPIPEPKEPS(1)PEK 109.22 0.0013285 151787000.0 106217.0 152602.0 114494.0 148061.0 164931.0 129767.0 132385.0 137463.0 118377.0 132230.0 True False 104702.32610218783 152248.65944483926 105080.74527962072 158949.89985701675 155230.0828468219 124217.16791165168 139239.2475352203 143850.0328133534 105044.13569492733 155085.77931460043 0.6751252536816618 0.9817061249438873 0.677565317361938 1.0249160210529538 1.0009304755913742 0.8009578212820532 0.8978208585634758 0.927551407028399 0.6773292571322046 1.0 17.24270687807133 -4.743840933139665 24.92242637750696 0.8842522975998215 0.6751245881944383 0.21185742231866955 0.12281222138176201 1749.773909704941 2477844.504430927 0.029313826770992372 0.8926207238176591 1.8036782440710986e-05 4.743840933139665 -0.20912770940538317 VPKPEPIPEPKEPS(ph)PEKNSK ddPTM_PC-9_AZD4547_30min_R2 1 VPKPEPIPEPKEPSPEKNSK 20 3 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 VPKPEPIPEPKEPS(0.995)PEKNS(0.005)K 58.864 0.02253 16014000.0 78118.0 44988.0 54618.0 88570.0 93936.0 69354.0 50151.0 49538.0 54659.0 80884.0 True False 102957.89904466 59529.49121171065 53893.72963323276 68151.55489285906 80894.6078533878 65017.28341631319 54614.34184463961 41883.04036999374 57548.16315143986 78052.27577917339 1.3190890081917657 0.7626874503971202 0.690482488758043 0.8731526943003483 1.0364157488790715 0.8329966393326059 0.6997149192568745 0.5366024238484709 0.7373028214354178 1.0 16.252153077190968 -7.106257656002259 4.046766972080048 0.7061883971496968 0.9114646525120763 0.1653929766655612 0.19264830161811614 0.40612274512143537 11.555939449811742 0.07662089957204928 0.059002969283815314 7.829649914933972e-08 7.106257656002259 0.20527625536237948 VPLAPITDPQQLQLS(ph)PLK ddPTM_PC-9_AZD4547_30min_R2 2 VPLAPITDPQQLQLSPLK 18 0 A0A286YFD6;P31350;P31350-2 A0A286YFD6 RRM2 Ribonucleoside-diphosphate reductase subunit M2 1 VPLAPITDPQQLQLS(1)PLK;VPLAPITDPQQLQLS(1)PLK 157.7 1.1347999999999999e-05 303080000.0 941420.0 671710.0 970180.0 898620.0 914760.0 922400.0 1257700.0 1385550.0 1460630.0 1245640.0 True False 1240771.9772475478 888827.1214950245 957314.7792956482 691457.0425406023 787761.3639069692 864722.1821842637 1369632.8635122606 1171445.0842715637 1537835.9198647558 1202030.5227433054 1.0322300089483798 0.7394380630755699 0.7964147009435663 0.5752408357838875 0.6553588690153389 0.7193845462515979 1.1394326829458945 0.9745551898283424 1.2793651165821203 1.0 20.19704209969217 -7.259398144471189 24.945390722232357 1.0962178569499488 0.7418478786438928 0.6099659360294208 0.13509926638180042 121.18213088663538 1480945.9749631425 0.05401748229228075 0.039731513532296946 5.5030296849501035e-08 7.259398144471189 -0.354369978306056 VPLAPITDPQQLQLS(ph)PLK ddPTM_PC-9_Lapatinib_30min_R1 2 VPLAPITDPQQLQLSPLK 18 0 A0A286YFD6;P31350;P31350-2 A0A286YFD6 RRM2 Ribonucleoside-diphosphate reductase subunit M2 1 VPLAPITDPQQLQLS(1)PLK;VPLAPITDPQQLQLS(1)PLK 151.31 5.8106e-05 534220000.0 1228210.0 1816840.0 1714470.0 1887340.0 2289900.0 1793420.0 1720110.0 1650850.0 1627680.0 2039980.0 True False 1210695.5001738714 1812633.2186063137 1573512.8946455892 2026141.2795816741 2155212.584116619 1716719.6072662112 1809168.8792371326 1727554.5177242227 1444353.53816974 2392587.824897509 0.5060192514461758 0.7576036289008372 0.6576614986799882 0.8468409219914289 0.900787240363451 0.717515816724408 0.7561556823163353 0.7220443486952148 0.6036783783398261 1.0 21.190140452120573 -12.018059047249118 2.3263042608227122 4.8551942204657506 0.7283391041214003 0.37857166206636694 0.10748475686420686 4641894.432226397 928193.3998174754 92417683.31134757 0.027808739274899474 9.592701990109728e-13 12.018059047249118 -4.12685511634435 VPLDLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 2 VPLDLSPR 8 0 R4GNG2;Q9UKV5 R4GNG2 AMFR E3 ubiquitin-protein ligase AMFR 1 VPLDLS(1)PR;VPLDLS(1)PR 84.81700000000001 0.013691 4794500.0 17053.2 16556.5 24966.0 24210.0 23115.0 15671.3 23387.0 26110.0 17789.1 17568.5 True False 22475.762871404782 21908.064844996166 24634.934527505386 18628.758540771363 19905.88124394329 14691.371133634242 25468.39769337775 22075.299448111287 18729.39550883256 16953.432162435223 1.3257352644620086 1.2922495359694324 1.4530942343397903 1.0988193046861783 1.174150523222666 0.8665720895257321 1.5022561478618863 1.302113886828468 1.1047553869553595 1.0 14.04928975099235 -1.5228787591186819 0.023552927750705367 1.9037048918517633e-08 2.850719239447627 0.1749399288116713 0.1723143235495818 4695.941059384288 8.542450876941903 363.62831315271205 728.4466595938442 0.029999999044081054 1.5228787591186819 2.850719220410578 VPLS(ph)PLSLLAGPADAR ddPTM_PC-9_Lapatinib_30min_R1 1 VPLSPLSLLAGPADAR 16 0 Q53ET0;H0YDQ8;Q5T4K5 Q53ET0 CRTC2 CREB-regulated transcription coactivator 2 1 VPLS(0.998)PLS(0.002)LLAGPADAR 161.94 3.4260999999999994e-15 0.0 0.0 445.84 0.0 0.0 418.43 0.0 0.0 0.0 0.0 0.0 True False 0.0 444.80768487232785 0.0 0.0 393.8187700650319 0.0 0.0 0.0 0.0 0.0 0.0 VPPAPVPCPPPS(ph)PGPSAVPSSPK ddPTM_PC-9_AZD4547_30min_R2 2 VPPAPVPCPPPSPGPSAVPSSPK 23 0 O95817 O95817 BAG3 BAG family molecular chaperone regulator 3 1 VPPAPVPCPPPS(0.996)PGPS(0.003)AVPS(0.001)SPK;VPPAPVPCPPPS(0.999)PGPS(0.001)AVPSSPK 104.01 1.5972e-06 23399000.0 163158.0 150132.0 197690.0 258230.0 225599.0 206255.0 183960.0 229900.0 191020.0 212807.0 True False 215038.8501027759 198659.2330087253 195068.50143164865 198699.06311372938 194278.47297219787 193357.8422445951 200332.08362225897 194374.23757643736 201116.92722494097 205356.6917034096 1.0471480053513422 0.9673862164454946 0.9499008764388361 0.9675801721655332 0.9460537728801569 0.9415706916619786 0.9755322895033413 0.9465201058905163 0.979354145008374 1.0 17.647772433830866 -4.763075697126059 4.753201971322647 0.9604678557202917 1.053382286508841 0.6691451751615077 0.01751787174371005 0.09859815957892623 5.371484916704957 0.004048439446963384 0.03098798005746047 1.725537106257776e-05 4.763075697126059 0.09291443078854922 VPPAPVPCPPPS(ph)PGPSAVPSSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VPPAPVPCPPPSPGPSAVPSSPK 23 0 O95817 O95817 BAG3 BAG family molecular chaperone regulator 3 1 VPPAPVPCPPPS(0.999)PGPS(0.001)AVPSSPK 99.219 0.00092145 0.0 13459.0 14753.0 20081.0 20708.0 31964.0 28287.0 29102.0 27233.0 30689.0 27585.0 True False 15737.342872632931 16217.580340819657 20559.80719761658 19547.79789624182 25700.883655493908 26803.579923582478 26345.247879765793 26518.16260574861 31137.76856711605 32585.94213726013 0.4829488374570639 0.4976864033118072 0.6309410085801275 0.5998843861534404 0.7887107743343852 0.822550405652815 0.8084850752141224 0.8137914961625932 0.9555583335892512 1.0 14.991962086859253 -5.04635306995311 0.2545048390171328 1.0173036345554884 0.0510486272313052 0.9380898802146694 0.042350562694206666 1.950200392176048 0.12057626800598188 0.06341720142944726 0.5895666722389283 8.987666109034342e-06 5.04635306995311 -0.9662550073241832 down VPPAPVPCPPPS(ph)PGPSAVPSSPK ddPTM_PC-9_Lapatinib_30min_R1 3 VPPAPVPCPPPSPGPSAVPSSPK 23 0 O95817 O95817 BAG3 BAG family molecular chaperone regulator 3 1 VPPAPVPCPPPS(0.98)PGPS(0.019)AVPS(0.001)SPK;VPPAPVPCPPPS(0.998)PGPS(0.001)AVPSSPK;VPPAPVPCPPPS(0.993)PGPS(0.005)AVPS(0.002)SPK 110.25 5.8235e-07 26605000.0 55516.0 60275.0 69696.0 75925.0 88910.0 91897.0 101219.0 96020.0 108418.0 87095.0 True False 54724.331659612464 60135.43694078494 63965.86391434022 81508.777778375 83680.48860378559 87966.77953237003 106459.62455162931 100481.43973824402 96206.82314784662 102149.25470320744 0.5357291330084873 0.5887016710548424 0.6262000060616372 0.7979380565741482 0.8191982295604362 0.8611592888069101 1.042196782159063 0.983672764232992 0.9418259920483372 1.0 16.640319152419757 -5.997133498325935 0.6783848712539801 0.9998219200452263 0.49335334425084315 0.9445527874032663 0.04061125153045894 0.21026991303713471 0.1866928321535851 0.024796029376210827 0.0657420902154371 1.0066221944294797e-06 5.997133498325935 -0.5064685757943832 VPPAPVPCPPPSPGPS(ph)AVPSSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VPPAPVPCPPPSPGPSAVPSSPK 23 0 O95817 O95817 BAG3 BAG family molecular chaperone regulator 3 1 VPPAPVPCPPPS(0.13)PGPS(0.464)AVPS(0.322)S(0.084)PK 80.172 0.00010925 11629000.0 22335.0 21377.0 18373.0 26492.0 29754.0 28078.0 30493.0 29932.0 29653.0 23789.0 True False 26115.874363641913 23499.167284328734 18811.081999990518 25007.739128222827 23923.91729087616 26605.540251505943 27604.4822897979 29146.31671557551 30086.619027035493 28101.757386379624 0.9293324258894844 0.8362170009950454 0.6693916590820717 0.8898994744130697 0.8513317143102096 0.9467571684467367 0.9823044840312106 1.0371706051985974 1.0706312282668091 1.0 14.778372733957802 -6.975760379291537 1.2624225412540955 1.0391566677424018 0.8189442277249408 0.6523818355509461 0.06537081754603262 0.28088963583169346 0.9188585124485579 0.0371745901992991 0.027529880817482262 1.0574007660695786e-07 6.975760379291537 -0.220212440017461 VPPAPVPCPPPSPGPSAVPS(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 1 VPPAPVPCPPPSPGPSAVPSSPK 23 0 O95817 O95817 BAG3 BAG family molecular chaperone regulator 3 1 VPPAPVPCPPPS(0.004)PGPS(0.037)AVPS(0.568)S(0.392)PK 80.98100000000001 9.0331e-05 15071000.0 14222.0 14670.0 14736.0 16100.0 12367.0 12235.0 15283.0 15998.0 12119.0 12087.0 True False 18744.30016402309 19411.79061251434 14540.591011668654 12388.393742520399 10650.055519958752 11469.943515854773 16643.157392905967 13525.87669746781 12759.585598571146 11663.837808996475 1.6070439653717885 1.6642713085003433 1.2466386492834545 1.0621198567220356 0.9130833002276678 0.9833764583907237 1.426902333987264 1.1596420422646068 1.0939440180426296 1.0 13.50975494313152 -5.375494007943621 3.280364431183217 1.1018528278437465 1.6417751183469582 0.7235589865206522 0.13234136023381451 0.13840325460571032 2.759425222434391 0.0393870191360918 0.09491072171953545 4.2121709833882e-06 5.375494007943621 0.5399222905032117 VPPAPVPCPPPSPGPSAVPS(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VPPAPVPCPPPSPGPSAVPSSPK 23 0 O95817 O95817 BAG3 BAG family molecular chaperone regulator 3 1 VPPAPVPCPPPS(0.004)PGPS(0.298)AVPS(0.659)S(0.039)PK 100.71 3.0317e-06 11076000.0 46964.0 47779.0 39881.0 51579.0 50980.0 37083.0 55264.0 48038.0 43436.0 42086.0 True False 54914.07761871857 52522.18335958942 40831.91428953474 48689.195851374214 40990.83496299211 35138.302199109436 50028.993843288335 46777.05340046824 44071.16932716131 49715.85864740732 1.1045585676831577 1.0564472743412718 0.8213056236063645 0.979349390235531 0.8245022026815537 0.7067825670741361 1.0062984971878253 0.940887971627292 0.8864609910435414 1.0 15.601418503822208 -5.139934296665749 5.163191111354969 0.8915924906089682 1.0925192029009312 0.41096100924910584 0.08895263509609015 0.2086152222700777 7.791057775137738 0.023216246890851305 0.06573957426605012 7.24545566484176e-06 5.139934296665749 0.20092671229196302 VPPAVIIPPAAPLS(ph)GR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VPPAVIIPPAAPLSGR 16 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 VPPAVIIPPAAPLS(1)GR 109.1 0.0040408 0.0 1240.1 2390.0 1712.2 1680.9 2020.1 1892.6 2082.6 3420.8 0.0 0.0 True False 1450.0244369085442 2627.263405040264 1753.0253415546606 1586.7246225513275 1624.275906409187 1793.3487242681144 1885.3210512817072 3331.0076246371996 0.0 0.0 0.0 VPPPPPIAR ddPTM_PC-9_Lapatinib_30min_R1 1 VPPPPPIAR 9 0 B4DY08;B2R5W2;G3V4W0;G3V576;G3V5V7;G3V555;G3V575;P07910-2;P07910;G3V4C1;G3V2Q1;P07910-4;G3V2D6;P07910-3 B4DY08;P07910-2 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 0 92.46700000000001 0.032282 10422000.0 18787.0 21220.0 18012.0 17948.0 17616.0 19410.0 14443.0 15256.0 19984.0 17980.0 False True 18519.093934886147 21170.866393752916 16531.122888330683 19267.955792772846 16579.86151438855 18579.879546919936 15190.787869858255 15964.84945476616 17733.19147915074 21087.81904315595 0.8781891525618206 1.003938166883309 0.783918092928432 0.9137007365883225 0.78622931467963 0.8810716513118997 0.7203584134883985 0.7570649872371487 0.8409210759472089 1.0 14.364122275139803 -5.2679703314750475 24.987838643422386 0.8252934963972465 0.9410636613055158 0.19921840367708665 0.08276743081893491 636.0444631836908 2433552.8988261195 0.0206699104616105 0.04469884638215051 5.395474800663552e-06 5.2679703314750475 0.1157701649082693 VPQALNFS(ph)PEESDSTFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VPQALNFSPEESDSTFSK 18 0 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 VPQALNFS(1)PEESDSTFSK 139.12 3.1572e-08 0.0 6788.6 10351.0 7687.9 8334.3 9389.8 5869.6 6379.4 5284.9 5184.5 5658.2 True False 7937.77589903826 11378.578872624172 7871.20869252311 7867.356191165162 7549.936095243296 5561.787843159742 5775.097049143628 5146.17697481441 5260.313504389625 6683.986869713449 1.1875810132132354 1.7023640372758522 1.1776218065581805 1.1770454288014551 1.1295557939309615 0.8321063388621203 0.8640198075959438 0.7699262543636674 0.7870023695326531 1.0 12.706493183977122 -6.2155788670763235 0.990951019533872 0.8226319646240333 1.4305635080328107 0.6853137080811686 0.14987652440295238 0.2888003596428168 0.5958978152351267 0.0655988976198644 0.10820561056894623 6.087249923884789e-07 6.2155788670763235 0.6079315434087774 VPQALNFS(ph)PEESDSTFSK ddPTM_PC-9_Lapatinib_30min_R1 1 VPQALNFSPEESDSTFSK 18 0 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 VPQALNFS(0.998)PEES(0.001)DSTFSK 132.87 6.8027e-06 0.0 4979.9 6286.2 7489.5 4585.6 4670.3 3483.4 5807.9 5838.8 5896.8 4869.8 True False 4908.885712798186 6271.644690122978 6873.742220306052 4922.840321113167 4395.60213616308 3334.4231022020067 6108.604643727047 6110.091963587353 5232.64028794316 5711.538441399382 0.8594682086382776 1.0980657408630459 1.2034834906270753 0.8619114397323436 0.769600376721988 0.5838047202891697 1.0695200087334753 1.0697804149052217 0.9161525115571336 1.0 12.479663682234769 -5.791697212829254 24.99279193583979 0.8877088553268276 1.058111957194603 0.17234034264356657 0.15772923771579128 348.78885891455815 288096.1396656883 0.04843333898833555 0.07184827019914444 1.6154844691197776e-06 5.791697212829254 0.1704031018677753 VPS(ph)GIFDVNSR ddPTM_PC-9_AZD4547_30min_R2 1 VPSGIFDVNSR 11 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 VPS(1)GIFDVNSR 77.67399999999999 0.019239 4129600.0 1686.4 1572.2 3161.3 5920.2 3746.1 4964.2 1378.3 4221.9 3877.2 3659.6 True False 2222.640120700925 2080.3829039533093 3119.379096443273 4555.389356178214 3226.0186773928604 4653.787789244484 1500.9660298791 3569.5023646105346 4082.1408765393217 3531.478517895547 0.6293794821171458 0.5890968594063645 0.88330683044963 1.2899382887632087 0.9135036957028655 1.3178015286406826 0.4250248224003199 1.0107671182260642 1.1559296922955435 1.0 11.78605660522744 -5.3749891903505045 4.156349265455265 1.0051652491394178 0.6102150741251885 0.316736344735123 0.2346323746720541 0.26888338131481276 7.779080296549348 0.06279234588518097 0.14034309179772012 4.217069996432833e-06 5.3749891903505045 -0.39495017501422935 VPS(ph)GIFDVNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VPSGIFDVNSR 11 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 VPS(1)GIFDVNSR;VPS(1)GIFDVNSR 91.307 0.008263600000000001 7233800.0 12509.6 12474.1 11833.7 14620.2 19801.9 14787.5 15815.8 15027.0 13595.0 16769.5 True False 14627.22820413768 13712.446209545084 12115.86028755717 13801.077593327936 15921.85984412854 14012.017468094022 14317.612927523869 14632.557172422585 13793.801155786854 19809.67760271105 0.7383879989109905 0.6922094586571398 0.611613198889166 0.6966836043530155 0.8037414925899428 0.7073319288233348 0.7227585029230579 0.7386570072407462 0.6963162870403861 1.0 14.273917780485844 -14.522878745272635 0.31462516954703856 3.631085019720241 0.6990568823950054 0.780183486410673 0.045836160788811274 147.9096856213315 1.3265443623198134 258.4662446569528 0.04500685450051756 3.0000000000532065e-15 14.522878745272635 -2.9320281373252355 VPS(ph)GIFDVNSR ddPTM_PC-9_Lapatinib_30min_R1 2 VPSGIFDVNSR 11 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 VPS(0.958)GIFDVNS(0.042)R;VPS(1)GIFDVNSR 109.95 0.0019966 6263400.0 6935.8 9710.099999999999 12393.4 9304.2 11477.4 11683.3 10386.400000000001 10113.599999999999 11318.599999999999 6804.4 True False 6836.894220130053 9687.61686003677 11374.462491907472 9988.461905901331 10802.321897436592 11183.63249410251 10924.156970954491 10583.514777512002 10043.780077858066 7980.53147370692 0.8566966050638665 1.2139062281696529 1.4252763151655221 1.251603597932023 1.3535842735570296 1.4013643741583748 1.3688508098672119 1.3261666610025922 1.2585352380287995 1.0 12.962269112431672 -4.793151372572899 3.3635065788698935 1.316807263270712 0.802480112540142 0.5647013479889083 0.11478160147830149 0.19134096758908495 3.4835379718056636 0.02680140281988568 0.2523476866805715 1.6100843453171982e-05 4.793151372572899 -0.51432715073057 VPS(ph)PDHRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VPSPDHRR 8 1 Q8NAV1-2;Q8NAV1 Q8NAV1-2 PRPF38A Pre-mRNA-splicing factor 38A 1 VPS(1)PDHRR 53.597 0.044527 8842100.0 15211.0 6518.9 12775.0 16512.0 15273.0 17456.0 18308.0 14605.0 16856.0 12178.0 True False 17785.921869055608 7166.053310090779 13079.6044494573 15586.88617262628 12280.36528814786 16540.57663046825 16573.73370155839 14221.634225276634 17102.487111580962 14385.774999005047 1.2363547928620964 0.49813467196493755 0.9092040192733388 1.0834929764787997 0.8536464173113508 1.1497869688363842 1.1520918200586807 0.9885900638832621 1.188847115484832 1.0 13.812355324443375 -6.226917024828723 1.181313233623334 1.090518108335774 0.8569031531113274 0.14149397286592524 0.19109674384754582 0.7927984438968765 2.2743330955686103 0.07614971176645559 0.1158291912216676 5.930386181688879e-07 6.226917024828723 -0.23361495522444664 VPS(ph)PGMEEAGCSR ddPTM_PC-9_Lapatinib_30min_R1 3 VPSPGMEEAGCSR 13 0 Q96RL1-2;Q96RL1-3;Q96RL1;Q96RL1-4 Q96RL1-2 UIMC1 BRCA1-A complex subunit RAP80 1 VPS(1)PGMEEAGCSR;VPS(1)PGMEEAGCSR;VPS(1)PGMEEAGCSR 78.985 0.014384000000000001 77262000.0 15231.8 38161.6 49197.7 45616.8 56783.9 41862.3 47535.4 37014.5 41499.600000000006 41237.0 True False 15014.591738829971 38073.239159841716 45152.85501461394 48971.611645183904 53443.98264344279 40071.94701478754 49996.55041950146 38734.32879807569 36825.47803783849 48364.7605051514 0.3104448689915615 0.787210331699802 0.9335899639119405 1.012547382302614 1.1050190693645716 0.8285360373183162 1.0337392328072472 0.8008791606432134 0.7614113592874332 1.0 15.561668634458222 -4.740962970379778 2.3772950206612142 0.9355295088055365 0.12066427954464412 0.7636804230601393 0.10425688626027095 0.3249070511651024 2.0448940152314514 0.028613983298466296 0.5771168445976083 1.815670467230561e-05 4.740962970379778 -0.8148652292608924 down VPS(ph)PGPPTLTSYSVLR ddPTM_PC-9_AZD4547_30min_R2 2 VPSPGPPTLTSYSVLR 16 0 F8W1U0;F8W130;Q12815 F8W1U0 TROAP Tastin 1 VPS(0.999)PGPPT(0.001)LTSYSVLR;VPS(0.785)PGPPT(0.137)LT(0.055)S(0.017)Y(0.004)S(0.001)VLR 88.10799999999999 0.0040788000000000005 23136000.0 31721.6 23999.0 19755.4 19823.0 15711.0 13241.4 17190.6 13488.6 13087.0 16250.6 True False 41808.40894973108 31756.20742397624 19493.43048805096 15253.113612297022 13529.79884160039 12413.413164760057 18720.53009739509 11404.246807192418 13778.752102359982 15681.671440297689 2.6660684168075783 2.025052466178529 1.2430709674198424 0.9726714190108978 0.8627778545871352 0.7915873771504303 1.1937841044984752 0.7272341376753094 0.8786532835366188 1.0 13.93679171770888 -5.065346969603261 1.4345056326525176 0.899277257746757 2.9316659752488348 0.9593146003448402 0.11963587305498666 0.1263627144453296 0.34436920495344536 0.035342126216549856 0.3181842208681025 8.603061557042721e-06 5.065346969603261 2.032388717502078 up VPS(ph)PGPPTLTSYSVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VPSPGPPTLTSYSVLR 16 0 F8W1U0;F8W130;Q12815 F8W1U0 TROAP Tastin 1 VPS(1)PGPPTLTSYSVLR;VPS(0.969)PGPPT(0.023)LT(0.002)S(0.003)Y(0.002)S(0.001)VLR;VPS(1)PGPPTLTSYSVLR 151.49 3.1137e-05 14673700.0 21152.2 29095.699999999997 13670.9 21450.4 18350.0 19945.2 19068.4 16500.2 21738.6 17524.7 True False 24732.849685006797 31984.128809217567 13996.866103176955 20248.603631135094 14754.449226577177 18899.238600482106 17262.10310873913 16067.087233407019 22056.485899609273 20701.78938455112 1.1947203802326327 1.54499344066779 0.6761186602363094 0.9781088607850382 0.7127137153461626 0.9129277788221446 0.8338459438497194 0.7761206983101284 1.0654386193335106 1.0 14.337467853778678 -5.260844547510396 24.99992602088875 0.8599835623060201 1.369856925848257 0.6632104947900976 0.14252355579097822 26.23531556521747 1102567.8377778933 0.0336993657133224 0.07891622984947448 5.484732517227073e-06 5.260844547510396 0.5098733635422368 VPS(ph)PGPPTLTSYSVLR ddPTM_PC-9_Lapatinib_30min_R1 1 VPSPGPPTLTSYSVLR 16 0 F8W1U0;F8W130;Q12815 F8W1U0 TROAP Tastin 1 VPS(0.998)PGPPT(0.001)LTSYSVLR 86.777 0.0044027 7333700.0 13869.0 10307.0 14534.0 10474.0 8022.2 7784.9 9309.4 9208.2 10289.0 8676.8 True False 13671.225516736897 10283.134774760196 13339.070622862419 11244.292900239736 7550.3499682520305 7451.957974488254 9791.395180755966 9636.046588186797 9130.144472026715 10176.573318890745 1.343401662655841 1.010471251228706 1.3107624939036344 1.1049193621360724 0.7419344146262217 0.732265934806877 0.9621505072419835 0.9468851927101464 0.8971727698437011 1.0 13.31296423486584 -6.07657676191165 5.417212343086611 0.8755644057703282 1.2021258912917732 0.6410145254504217 0.11656165752996096 0.1425324450394511 7.377528896636025 0.03481498918736388 0.0458841564304453 8.383458871914113e-07 6.07657676191165 0.3265614855214449 VPS(ph)PPDEHQEAENAVSSGNR ddPTM_PC-9_AZD4547_30min_R2 4 VPSPPDEHQEAENAVSSGNR 20 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6;Q9BXS6-7 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 VPS(1)PPDEHQEAENAVSSGNR;VPS(1)PPDEHQEAENAVSSGNR;VPS(1)PPDEHQEAENAVSSGNR;VPS(1)PPDEHQEAENAVSSGNR 100.27 0.00020555 10323700.0 26554.199999999997 34972.5 38447.600000000006 51743.1 40718.100000000006 39824.7 30454.2 40002.2 24647.899999999998 37558.7 True False 34997.8832383281 46276.676700487915 37937.75970278445 39814.52771792592 35065.09466056706 37334.45521339284 33164.56480239722 33820.779149109025 25950.73767431484 36243.78134497854 0.9656244999716881 1.2768170147593996 1.0467384553968624 1.098520249279732 0.9674789262965582 1.030092717369442 0.915041520826084 0.9331470915573986 0.7160052486606846 1.0 15.14544586040432 -6.844286053431181 0.8594891835038694 0.8684844412270051 1.116233290904724 0.42741082594381585 0.10257299944221841 0.5245744614973501 0.8327580876804062 0.06492570780694751 0.055886433869786416 1.431244881601845e-07 6.844286053431181 0.24774884967771882 VPS(ph)PPDEHQEAENAVSSGNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VPSPPDEHQEAENAVSSGNR 20 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6;Q9BXS6-7 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 VPS(1)PPDEHQEAENAVSSGNR;VPS(0.999)PPDEHQEAENAVSS(0.001)GNR;VPS(1)PPDEHQEAENAVSSGNR;VPS(1)PPDEHQEAENAVSSGNR 87.323 0.0014229000000000002 8382400.0 30956.299999999996 35415.6 36755.9 36514.0 48060.799999999996 30771.2 42744.8 32600.3 24558.0 23977.9 True False 36196.59017520519 38931.42671445353 37632.30005352702 34468.23895998523 38643.63124733952 29157.504102398296 38695.70309844727 31744.576667873047 24917.11429082853 28324.903461048038 1.2779069212003553 1.3744592904964856 1.3285941152554452 1.2168881354665662 1.3642987804170856 1.0293946506294447 1.366137157419124 1.1207302687378156 0.8796892926782311 1.0 14.7897834185077 -8.018967398937257 4.16864304361101 0.9480224162000285 1.2759494798335675 0.646650757442422 0.1004811569146019 0.12953135792394244 5.165785825145547 0.06747502834356912 0.026013620121418897 9.5726592741219e-09 8.018967398937257 0.3279270636335391 VPS(ph)PPDEHQEAENAVSSGNR ddPTM_PC-9_Lapatinib_30min_R1 2 VPSPPDEHQEAENAVSSGNR 20 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6;Q9BXS6-7 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 VPS(1)PPDEHQEAENAVSSGNR;VPS(1)PPDEHQEAENAVSSGNR 95.429 0.00039361 4046200.0 16887.6 19067.7 19543.6 13863.2 17523.8 13345.2 16920.1 19084.1 16186.0 6039.0 True False 16646.779727193454 19023.549912166007 17936.80064847764 14882.745974279509 16493.084537116374 12774.456905180627 17796.139987314873 19970.81695593229 14362.962233863778 7082.833103538306 2.350299588292907 2.6858673124265184 2.5324330513332467 2.101241940438307 2.3285999113655627 1.8035801096031767 2.5125736731569486 2.8196085752685107 2.0278555238988485 1.0 12.790110832380488 -8.543606501385778 22.336919111128214 0.9999999900153141 2.3816991770415856 0.7038200327140128 0.2721791909745554 641.4223315265351 691217.9717774425 0.27715821020985637 0.07156194270123249 2.8601808767433003e-09 8.543606501385778 1.3816991870262716 VPS(ph)PPPGHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VPSPPPGHK 9 0 P11387 P11387 TOP1 DNA topoisomerase 1 1 VPS(1)PPPGHK 61.958 0.036085 4554600.0 56457.0 61167.0 56395.0 68618.0 56700.0 55386.0 57231.0 52343.0 54653.0 46631.0 True False 66014.05502342204 67239.2555213797 57739.67067922852 64773.55592255757 45590.04202435565 52481.460658519405 51809.665363441585 50969.0517119928 55452.19673168217 55084.83116920713 1.1984071408087467 1.2206492076709312 1.0481954733031018 1.175887345893628 0.8276333258481666 0.9527388855438114 0.9405432360189135 0.925282888776192 1.0066690875632638 1.0 15.749367474937415 -6.245714493056942 24.953461136652436 0.9388583641180627 1.1570187464009694 0.7458732685305194 0.062488222703283365 402.5336158885002 638771.1825231655 0.01845473018788731 0.023743762553684905 5.679178341875425e-07 6.245714493056942 0.21816038228290668 VPS(ph)PPPGHK ddPTM_PC-9_Lapatinib_30min_R1 1 VPSPPPGHK 9 0 P11387 P11387 TOP1 DNA topoisomerase 1 1 VPS(1)PPPGHK 63.693999999999996 0.031974 4909600.0 74545.0 91414.0 93469.0 64084.0 72131.0 92931.0 82508.0 75791.0 77201.0 55651.0 True False 73481.97463012143 91202.33649945944 85784.33962077406 68796.9511379571 67888.39639500223 88956.55776274178 86779.86052525537 79312.52654864875 68505.81041742978 65270.20119970364 1.1258119827958348 1.397304356706557 1.31429562103393 1.054033079007415 1.040113177946056 1.362896944205309 1.3295479243236865 1.2151414441941213 1.0495725332273196 1.0 15.994136866060945 -8.302394808771298 3.552501694009057 1.0065807634350998 1.2350275868161684 0.3272109278392854 0.118666490273088 0.2960317858005296 7.332653741219254 0.11817468685330108 0.03284149697747906 4.984311672389197e-09 8.302394808771298 0.2284468233810686 VPS(ph)PSALLVDNPTPFGNAK ddPTM_PC-9_AZD4547_30min_R2 1 VPSPSALLVDNPTPFGNAK 19 0 Q9P0V3;Q9P0V3-2;C9JF25;C9JED2 Q9P0V3 SH3BP4 SH3 domain-binding protein 4 1 VPS(0.74)PS(0.26)ALLVDNPTPFGNAK 148.36 0.00012867 5671700.0 10204.0 16729.0 18554.0 11119.0 13087.0 14201.0 15382.0 17844.0 16757.0 14253.0 True False 13448.659743614946 22136.32209657479 18307.961837031755 8555.68633683754 11270.095948063421 13313.00922506363 16750.968201117554 15086.619814327762 17642.74080990647 13754.006808275562 0.9777994100979437 1.609445335104511 1.3311002453493153 0.6220504654461653 0.8194045637146542 0.9679367918484241 1.2178973323641782 1.096889075643789 1.2827346282314707 1.0 13.747564344393766 -5.590291874419538 24.99999532977908 1.002922592521481 1.3378017812306544 0.27145341959596836 0.2273115787689797 64.60419602074725 23957.38798827824 0.06433537707626287 0.11143216160860389 2.568668888318338e-06 5.590291874419538 0.3348791887091733 VPS(ph)PSALLVDNPTPFGNAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VPSPSALLVDNPTPFGNAK 19 0 Q9P0V3;Q9P0V3-2;C9JF25;C9JED2 Q9P0V3 SH3BP4 SH3 domain-binding protein 4 1 VPS(0.5)PS(0.5)ALLVDNPTPFGNAK 83.792 0.0014280999999999999 3872200.0 30920.0 53819.0 38021.0 32816.0 48803.0 37932.0 51681.0 38543.0 40507.0 38426.0 True False 36154.14530216289 59161.79464262003 38927.564835445475 30977.42591090747 39240.40248526684 35942.77914453034 46785.40154196194 37531.287089684185 41099.33824328492 45392.329619951386 0.796481379230027 1.3033434313231749 0.8575802379249459 0.6824374551882858 0.8644720994451763 0.7918249502826207 1.0306895886083418 0.8268200245265221 0.9054247399811892 1.0 15.47016091155526 VPS(ph)PTPAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VPSPTPAPK 9 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 VPS(0.712)PT(0.288)PAPK;VPS(0.808)PT(0.192)PAPK 86.344 0.011734999999999999 95926000.0 119461.0 113794.0 126940.0 139494.0 155769.0 107663.0 134155.0 133940.0 115910.0 94328.0 True False 139683.3878376998 125090.71628165338 129966.73102263067 131678.60342564978 125247.18264712294 102016.96275012044 121446.8672019096 130424.21692116064 117604.96446982381 111428.91969996263 1.253564947177233 1.1226054835537935 1.166364453434383 1.1817273628804097 1.1240096644961457 0.915533983680492 1.089904376071505 1.1704700832813009 1.0554258695721992 1.0 16.76576418550841 -6.528787450067162 24.9974973815763 1.0552178328527628 1.1729683712055987 0.46405663644799156 0.06797016091588877 164.85070343412096 697414.7247514646 0.023235900586562146 0.023297541970086613 2.959460514491363e-07 6.528787450067162 0.11775053835283589 VPS(ph)PTPAPK ddPTM_PC-9_Lapatinib_30min_R1 2 VPSPTPAPK 9 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 VPS(0.934)PT(0.066)PAPK;VPS(0.934)PT(0.066)PAPK 67.214 0.046353 123493000.0 985240.0 849810.0 962200.0 823650.0 951230.0 881170.0 880960.0 847570.0 919790.0 805240.0 True False 971190.2969291107 847842.3171571699 883091.6301994113 884223.9686158529 895280.521590136 843484.4132075971 926571.7982296138 886951.1964064079 816193.5643819083 944424.6610851426 1.0283406786659026 0.8977341995527734 0.9350577834178326 0.936256755091381 0.9479639387661266 0.8931198516549056 0.9810965727694828 0.939144468535269 0.8642230534769211 1.0 19.84907618855813 -4.7486467072461656 24.995052228672673 0.9317634152320917 1.028340906911313 0.3593593673555182 0.03827660934513338 661.846306270168 1293076.4572453192 0.008963621559678895 0.15943288193410646 1.7838292986561062e-05 4.7486467072461656 0.09657749167922125 VPS(ph)SDEEVVEEPQSR ddPTM_PC-9_AZD4547_30min_R2 2 VPSSDEEVVEEPQSR 15 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 VPS(0.905)S(0.095)DEEVVEEPQSR;VPS(0.973)S(0.027)DEEVVEEPQSR 208.38 4.6788e-13 33478000.0 4766.9 3852.5 4404.799999999999 14639.7 10725.400000000001 8462.6 3513.1000000000004 15224.9 9526.7 4852.6 True False 6282.6750423204685 5097.7452852564065 4346.389473954808 11264.743346110312 9236.363343880137 7933.432284206994 3825.7590942235142 12872.241538397146 10030.261912856487 4682.711951016487 1.3416744630121171 1.0886309767889584 0.9281778421180332 2.4056024508757257 1.9724389286586759 1.6941960913237182 0.816996461504118 2.7488860457459783 2.1419771315805995 1.0 12.193128580520712 -5.742988090866255 24.99960412100522 1.8572004517616096 1.1164078824174122 0.2500465702315856 0.5586198448951413 340.75623597639196 461686.1400116927 0.1537605771330461 0.2656983809663818 1.8072236826466897e-06 5.742988090866255 -0.7407925693441975 VPS(ph)SDEEVVEEPQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VPSSDEEVVEEPQSR 15 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 VPS(0.817)S(0.183)DEEVVEEPQSR;VPS(0.5)S(0.5)DEEVVEEPQSR 187.08 3.3632e-07 43660000.0 18102.4 16396.6 16762.8 17394.6 21979.1 22078.7 21283.3 23092.3 14534.1 13662.7 True False 21166.7787813025 18024.346086645673 17162.48872527302 16420.03695605408 17672.45313328952 20920.854104670012 19267.19174625179 22486.15159331431 14746.633716684208 16139.639356126308 1.3114778040729875 1.1167750213578327 1.0633749829582442 1.0173732258658763 1.0949719967925668 1.2962404947870687 1.1937808101603162 1.3932251580813038 0.9136904109995901 1.0 13.97832072117994 VPS(ph)SDEEVVEEPQSR ddPTM_PC-9_Lapatinib_30min_R1 2 VPSSDEEVVEEPQSR 15 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 VPS(0.5)S(0.5)DEEVVEEPQSR;VPS(0.979)S(0.021)DEEVVEEPQSR 202.32 1.0901000000000001e-10 26704000.0 7007.0 10920.2 11359.1 8283.7 9964.0 10962.8 8026.2 11018.6 9347.5 8170.8 True False 6907.078895073578 10894.914947835085 10425.198645394019 8892.910931613125 9377.937109977716 10493.94659953498 8441.757363501783 11530.564381376938 8294.68611646125 9583.111893093366 0.720755321666605 1.1368869600371823 1.0878719524195009 0.927977365893257 0.9785899626964054 1.095045817747162 0.8808993840075928 1.2032171292591416 0.8655524644806979 1.0 13.22627849842335 -4.747466143515028 24.991951152018455 1.0219288917976475 0.7207545622776977 0.4191090249658045 0.10550086530012961 681.1795924685474 1218259.7705677166 0.024526853046649325 0.5005856647573383 1.7886849649692096e-05 4.747466143515028 -0.3011743295199497 VPS(ph)TPPPK ddPTM_PC-9_AZD4547_30min_R2 2 VPSTPPPK 8 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 VPS(0.937)T(0.063)PPPK;VPS(0.946)T(0.054)PPPK 101.46 0.0045792 193217000.0 377390.0 360270.0 469870.0 618890.0 546990.0 494050.0 440310.0 532830.0 442050.0 521380.0 True False 497392.16980035725 476720.23203616485 463639.21679239604 476214.4722551831 471049.8802346752 463156.975399105 479496.7370065057 450493.36671532394 465415.86053703853 503126.6448957204 0.9886023227878307 0.947515375845323 0.9215159274430622 0.9465101423000263 0.9362451482415654 0.9205574383664382 0.9530338769990758 0.8953876151971529 0.9250471332789423 1.0 18.940562069230225 -4.801339194598521 3.1742545106546434 0.933784065947404 0.995397511988169 0.2482405580606153 0.026097948086283105 0.40043693446790696 6.272951312792912 0.006201524119320297 0.060558837203751305 1.580013528082317e-05 4.801339194598521 0.06161344604076491 VPS(ph)TPPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VPSTPPPK 8 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 VPS(0.93)T(0.07)PPPK;VPS(0.911)T(0.089)PPPK;VPS(0.737)T(0.263)PPPK 85.807 0.025435 275282000.0 698900.0 712860.0 812670.0 780420.0 939230.0 777350.0 814390.0 796110.0 745640.0 600080.0 True False 817209.9660957854 783628.0296723859 832047.1348681382 736695.5975557779 755194.6238189712 736584.397553534 737245.0835269892 775212.956048269 756543.574387709 708869.7537693325 1.152835146019937 1.1054612296624802 1.1737658863900233 1.0392538172752959 1.0653503267748574 1.0390969478339738 1.0400289751492064 1.0935901157104873 1.0672532864674737 1.0 19.435161048512732 -5.769497648124053 24.999990583034595 1.0529911070371891 1.1401648045634742 0.7044707262464361 0.028028897875806057 97.56124604311732 302674.5504314311 0.00765046710125767 0.011569555622438587 1.7002091609207579e-06 5.769497648124053 0.08717369752628512 VPS(ph)TPPPK ddPTM_PC-9_Lapatinib_30min_R1 4 VPSTPPPK 8 0 Q9H7N4 Q9H7N4 SCAF1 Splicing factor, arginine/serine-rich 19 1 VPS(0.988)T(0.012)PPPK;VPS(0.949)T(0.051)PPPK;VPS(0.941)T(0.059)PPPK;VPS(0.938)T(0.062)PPPK 96.66799999999999 0.0060493000000000005 360427000.0 720830.0 613330.0 678980.0 584380.0 633300.0 639170.0 549490.0 554540.0 653620.0 501340.0 True False 710550.8320159672 611909.8720678834 623156.8853385951 627357.2546345341 596050.539115705 611834.189078043 577939.903524781 580305.9528478005 580002.4326762666 587995.9510064399 1.2084281036285318 1.0406702138348256 1.0597979191386815 1.0669414535265451 1.0136983734249845 1.0405415003807432 0.9828977606657895 0.9869216817811809 0.9864054874587297 1.0 19.16544669500348 -1.5228787452803376 0.5356502580112504 0.9996270570800184 8.376305053198864 0.8072366743351749 0.0280131768906526 56.24639221430348 0.5387213709758585 0.014681790803983163 474.59794945394265 0.029999999999999995 1.5228787452803376 7.376677996118846 VPS(ph)VESLFR ddPTM_PC-9_AZD4547_30min_R2 3 VPSVESLFR 9 0 Q13439-3;Q13439-4;Q13439;Q86W71;Q13439-5;E7EVX2 Q13439-3;Q13439-5 GOLGA4 Golgin subfamily A member 4 1 VPS(0.972)VES(0.028)LFR;VPS(0.767)VES(0.233)LFR;VPS(1)VESLFR 144.55 0.00054254 101382900.0 8548.199999999999 5945.799999999999 13596.0 21716.5 20091.3 18095.100000000002 18985.6 15645.500000000002 13459.1 12512.400000000001 True False 11266.349786394474 7867.663573543815 13415.708156531406 16710.096441580394 17301.9697960821 16963.61053647271 20675.281620019327 13227.847472823634 14170.520548702776 12074.344684478152 0.9330816769607071 0.651601704203283 1.111092030839372 1.3839340252611478 1.4329531124222568 1.4049301208271634 1.712331572461889 1.0955333658669142 1.1736057665240671 1.0 13.559657270796112 -5.496971282393325 3.7368362386183462 1.341851337370126 0.7969434135328431 0.5142637932093004 0.19994758807928245 0.1664108382192556 4.956725008127282 0.0553821388255201 0.11592463946435846 3.1844080828987577e-06 5.496971282393325 -0.5449079238372828 VPS(ph)VESLFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VPSVESLFR 9 0 Q13439-3;Q13439-4;Q13439;Q86W71;Q13439-5;E7EVX2 Q13439-3;Q13439-5 GOLGA4 Golgin subfamily A member 4 1 VPS(0.974)VES(0.026)LFR;VPS(0.993)VES(0.007)LFR;VPS(0.976)VES(0.024)LFR;VPS(0.961)VES(0.039)LFR 108.31 0.0024439 171861000.0 17383.5 22170.5 25513.300000000003 30165.0 26018.399999999998 25343.9 27020.8 25478.4 26229.9 21973.300000000003 True False 20326.18321022472 24371.44072026995 26121.633831729057 28474.95284624949 20920.28129464719 24014.821268613916 24461.194210348956 24809.618996596244 26613.462665404466 25956.88534945291 0.7830748156636264 0.938920074275538 1.0063470050454115 1.0970096166352892 0.8059626959475754 0.9251811588835358 0.9423778654885695 0.9558010779255206 1.0252949191365672 1.0 14.663829659632192 -4.773103912452858 4.037260136162876 0.9647728582324451 0.765688043594836 0.3743855569333311 0.07178014668219035 0.26634730967172776 8.279258193675135 0.018693224362880487 0.15691084104406744 1.68614953673194e-05 4.773103912452858 -0.19908481463760908 VPS(ph)VESLFR ddPTM_PC-9_Lapatinib_30min_R1 4 VPSVESLFR 9 0 Q13439-3;Q13439-4;Q13439;Q86W71;Q13439-5;E7EVX2 Q13439-3;Q13439-5 GOLGA4 Golgin subfamily A member 4 1 VPS(0.997)VES(0.003)LFR;VPS(0.973)VES(0.027)LFR;VPS(1)VESLFR;VPS(1)VESLFR 144.55 0.00054254 149153000.0 18586.6 14972.0 15422.5 14158.2 20816.4 20272.3 14590.599999999999 14937.7 18599.499999999996 13060.1 True False 18321.551675634997 14937.333253876946 14154.521582571608 15199.44125837065 19592.020278617038 19405.300986039423 15346.029875645896 15631.760074754897 16504.628448582076 15317.52088351062 1.1961172969810165 0.9751795585901275 0.9240739209834545 0.992291205212778 1.2790594788552196 1.2668695628761515 1.0018612014536874 1.0205150163420085 1.0774999801925769 1.0 13.902895197799026 -4.155255800555747 5.1702455441056925 1.0662043001664285 11.561396377323872 0.11106054215310734 0.11416841436114435 2176.383913420852 540.5964872235968 0.03198063513790304 263816.80694982526 6.994299086566816e-05 4.155255800555747 10.495192077157444 VPS(ph)WGLEDNVVCSQPAR ddPTM_PC-9_AZD4547_30min_R2 3 VPSWGLEDNVVCSQPAR 17 0 H7C3L5;B8ZZD4;Q86VP1-3;Q86VP1-4;Q86VP1-2;Q86VP1 H7C3L5 TAX1BP1 Tax1-binding protein 1 1 VPS(1)WGLEDNVVCSQPAR;VPS(1)WGLEDNVVCSQPAR;VPS(1)WGLEDNVVCSQPAR 192.24 3.4889000000000002e-09 34602700.0 1963.7 4662.299999999999 2665.7 5209.7 8604.3 4701.4 3126.5 6883.5 4731.9 3942.1 True False 2588.115752502613 6169.297298754296 2630.3510762625615 4008.684154062641 7409.7414660290415 4407.420714788689 3404.7524431669517 5819.813242093991 4982.018573634687 3804.088278881854 0.6803511282507211 1.6217545037013847 0.6914537422448324 1.0537831564836673 1.9478363599403659 1.1586010606683854 0.8950245613563206 1.5298838553254144 1.3096485171734933 1.0 11.893335010888766 -4.7332117551250565 24.48665499927193 1.2468918352405667 0.6803471098275177 0.18635231391348084 0.3541513956782574 4457.148366300916 3866179.6065070317 0.08837908835066158 8.518091733327005 1.848367164613721e-05 4.7332117551250565 -0.566544725413049 VPS(ph)WGLEDNVVCSQPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VPSWGLEDNVVCSQPAR 17 0 H7C3L5;B8ZZD4;Q86VP1-3;Q86VP1-4;Q86VP1-2;Q86VP1 H7C3L5 TAX1BP1 Tax1-binding protein 1 1 VPS(1)WGLEDNVVCSQPAR;VPS(1)WGLEDNVVCSQPAR 229.69 2.4484e-29 20868400.0 0.0 0.0 4240.7 6626.200000000001 2277.6 4404.6 4673.4 1279.4 1422.1 3640.2 True False 0.0 0.0 4341.814370944307 6254.955496430249 1831.3206298884024 4173.615022144848 4230.701719514037 1245.817105636353 1442.895522151121 4300.139444192655 0.0 0.0 1.0096915291451616 1.4545936422777117 0.4258747079380423 0.9705766699685335 0.9838522155898005 0.2897155131373312 0.3355462167860053 1.0 12.070167728705508 -5.2521849531951625 24.43327293355767 0.8047915801807403 1.9475787975550242e-07 0.4676835895537139 0.34510188140816 447.6040342144144 1181742.2123718183 0.09375232061878241 0.24052913882500032 5.595192680154266e-06 5.2521849531951625 -0.8047913854228606 VPS(ph)WGLEDNVVCSQPAR ddPTM_PC-9_Lapatinib_30min_R1 4 VPSWGLEDNVVCSQPAR 17 0 H7C3L5;B8ZZD4;Q86VP1-3;Q86VP1-4;Q86VP1-2;Q86VP1 H7C3L5 TAX1BP1 Tax1-binding protein 1 1 VPS(1)WGLEDNVVCSQPAR;VPS(1)WGLEDNVVCSQPAR;VPS(1)WGLEDNVVCSQPAR;VPS(1)WGLEDNVVCSQPAR 184.92 3.4173e-08 33258100.0 22055.9 16422.7 18639.0 18559.8 17493.5 14053.0 17304.95 15298.7 13532.1 10726.98 True False 21741.378821443308 16384.674247157687 17106.573368620666 19924.749605677804 16464.56672354427 13451.985949143016 18200.91563722936 16009.533452650194 12007.97239866973 12581.124200197617 1.7280950792220784 1.3023219536216268 1.3597014937943277 1.583701844813267 1.3086721394329495 1.0692197084368438 1.446684362033678 1.2725042053395137 0.9544435145534225 1.0 13.618973221129574 -1.522878745280505 0.10834851343084874 0.8055659604417202 3.1354233347685727 0.5465903191242412 0.15824232659527543 94.66706518937734 0.7206297258393556 1.5795025366352886 32.92666036195006 0.029999999999988432 1.522878745280505 2.3298573743268527 VPS(ph)YDSFDSEDYPAALPNHKPK ddPTM_PC-9_AZD4547_30min_R2 1 VPSYDSFDSEDYPAALPNHKPK 22 1 P14921-4;P14921;P14921-3 P14921-4 ETS1 Protein C-ets-1 1 VPS(0.957)YDS(0.043)FDSEDYPAALPNHKPK 110.33 7.262799999999999e-06 14271000.0 72689.0 50207.0 84202.0 105400.0 103680.0 98557.0 78234.0 123570.0 117190.0 109170.0 True False 95802.58997487504 66435.43089860312 83085.42646339053 81101.6584137671 89285.8216470708 92394.21520981613 85196.67444065989 104475.09585611307 123384.42415187313 105347.99152876188 0.9093917082293802 0.630628357831246 0.7886759420629934 0.7698453215562719 0.8475322628499679 0.8770382222673022 0.8087166466519646 0.9917141688229482 1.1712081299450972 1.0 16.68480328371195 -7.866112084962182 3.0674772343122423 1.0874515258553714 0.7984314404710378 0.675183014988026 0.08087102795697797 0.14368302111287104 2.64350986334131 0.05223920439682874 0.022077636043764493 1.3610933591306852e-08 7.866112084962182 -0.28902008538433366 VPS(ph)YDSFDSEDYPAALPNHKPK ddPTM_PC-9_Lapatinib_30min_R1 2 VPSYDSFDSEDYPAALPNHKPK 22 1 P14921-4;P14921;P14921-3 P14921-4 ETS1 Protein C-ets-1 1 VPS(0.739)Y(0.012)DS(0.245)FDS(0.004)EDYPAALPNHKPK;VPS(0.968)Y(0.001)DS(0.03)FDSEDYPAALPNHKPK 68.406 0.00096041 17913600.0 172204.0 143036.0 168756.0 153805.0 200483.0 173789.0 152358.0 144637.0 188928.0 177543.0 True False 169748.33938165367 142704.80893010533 154881.53309699806 165116.33277843942 188690.9841047433 166356.44959194574 160246.3517465806 151357.36304332837 167648.93913996173 208231.07098882305 0.8151921736538782 0.6853194782721216 0.7437964582399493 0.7929476230149254 0.9061615214708827 0.7989031070241916 0.7695602341457579 0.7268721345214259 0.805110103616383 1.0 17.667825829418973 -8.564949292519286 20.96045218212386 1.0000000009629135 0.779529024586744 0.5824353901263324 0.05557647262906575 2098.705059719388 1045619.2107515897 0.058253769749052935 0.01504105866882397 2.7230192245839684e-09 8.564949292519286 -0.22047097637616953 VPSPS(ph)ALLVDNPTPFGNAK ddPTM_PC-9_AZD4547_30min_R2 1 VPSPSALLVDNPTPFGNAK 19 0 Q9P0V3;Q9P0V3-2;C9JF25;C9JED2 Q9P0V3 SH3BP4 SH3 domain-binding protein 4 1 VPS(0.228)PS(0.772)ALLVDNPTPFGNAK 112.91 9.8755e-05 7144600.0 13617.0 17552.0 18004.0 14602.0 13216.0 18875.0 13697.0 26043.0 16174.0 18252.0 True False 17946.92274880485 23225.340751932632 17765.255196395374 11235.73449865111 11381.186524765506 17694.743266183796 14916.006465395089 22018.65275860444 17028.92462012457 17613.003035476435 1.0189587041264814 1.3186474052807307 1.008644304472796 0.6379227026771009 0.6461809210979701 1.0046409025503895 0.8468746888506743 1.2501362041586017 0.9668382266115889 1.0 14.104353290707419 -5.51592441329401 24.89405305520851 0.9020069513596572 1.1675137980182002 0.24673103375053573 0.18129270093485375 407.96236662466663 1460358.8350070142 0.05252295335169626 0.09583270984062177 3.0484255061357606e-06 5.51592441329401 0.26550684665854296 VPSPS(ph)ALLVDNPTPFGNAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VPSPSALLVDNPTPFGNAK 19 0 Q9P0V3;Q9P0V3-2;C9JF25;C9JED2 Q9P0V3 SH3BP4 SH3 domain-binding protein 4 1 VPS(0.163)PS(0.837)ALLVDNPTPFGNAK 182.28 3.6417e-37 0.0 18927.0 31031.0 27946.0 24062.0 36667.0 27857.0 35775.0 26387.0 21304.0 23680.0 True False 22130.96727471012 34111.55260326546 28612.338625795186 22713.88415005655 29482.364566261902 26396.129880554217 32386.133011429498 25694.369209337518 21615.5306967917 27972.996549223153 0.7911546850465946 1.2194457802631367 1.0228556878218966 0.8119932417711375 1.0539580382238551 0.9436289685342013 1.1577641656817386 0.9185418932191977 0.7727284654239873 1.0 14.77174718735511 -7.9889871001016495 24.941638040975896 0.8727878349947031 1.0046639169144858 0.10830905147162473 0.136000016309466 370.87873706164396 839953.31839031 0.07168305505574 0.03438766287099046 1.0256823917595892e-08 7.9889871001016495 0.13187608191978262 VPSRAPS(ph)PAPPPLPSSR ddPTM_PC-9_AZD4547_30min_R2 1 VPSRAPSPAPPPLPSSR 17 1 Q6UXY1;B0QYF0;Q6UXY1-2 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 VPS(0.001)RAPS(0.992)PAPPPLPS(0.004)S(0.003)R 60.669 0.016392 6373300.0 10121.0 7382.5 10916.0 48515.0 30374.0 11946.0 8791.2 13235.0 8799.7 17568.0 True False 13339.267470122184 9768.748752344041 10771.24670761231 37330.61629927811 26157.094393404 11199.014731540747 9573.59976918897 11189.834860044155 9264.834177056402 16952.949667283032 0.7868405045680764 0.5762270840216346 0.6353612155411164 2.2020130438611107 1.5429229076214248 0.6605938760706271 0.5647158728763739 0.6600523849627813 0.5465027832257602 1.0 14.049248691266964 -6.810655093386969 20.183199860176213 0.6575134093572356 1.1468705640373817 0.19963554724940402 0.46101284647625435 30.95569737650852 12693.36535765849 0.18188275259385628 0.16040783482584195 1.546482132242033e-07 6.810655093386969 0.4893571546801462 VPSRAPS(ph)PAPPPLPSSR ddPTM_PC-9_Lapatinib_30min_R1 1 VPSRAPSPAPPPLPSSR 17 1 Q6UXY1;B0QYF0;Q6UXY1-2 Q6UXY1 BAIAP2L2 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 1 VPS(0.001)RAPS(0.997)PAPPPLPS(0.001)S(0.001)R 56.553000000000004 0.022886 4651800.0 82896.0 13140.0 21684.0 15566.0 13659.0 14887.0 7555.8 8274.3 17787.0 12223.0 True False 81713.8878387354 13109.575137319189 19901.225222660574 16710.775566653785 12855.604474627218 14250.317713291968 7947.0023531866655 8658.754184817235 15783.640754586373 14335.729263876272 5.700016116001942 0.9144686605063899 1.3882255207489482 1.1656732112514323 0.8967527384198912 0.9940420505289865 0.5543493607410563 0.6039981660811564 1.1010001977617285 1.0 13.807327676427631 -4.761165944286705 24.999954806464977 0.9518300266530146 5.700021395475787 0.9737368596908533 0.23365177464169026 1.0153881225132881 92671.41977631794 0.06466313632814066 0.36590359189476046 1.7331416363412393e-05 4.761165944286705 4.748191368822772 VPSS(ph)DEEVVEEPQSR ddPTM_PC-9_AZD4547_30min_R2 2 VPSSDEEVVEEPQSR 15 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 VPS(0.125)S(0.875)DEEVVEEPQSR;VPS(0.029)S(0.971)DEEVVEEPQSR 239.87 2.6212e-32 48641000.0 13073.400000000001 10110.8 16334.2 21441.3 15915.2 15445.8 13431.0 16452.2 12287.7 13552.0 True False 17230.46925638727 13378.918372529652 16117.597835423318 16498.339549782777 13705.649196348963 14479.971684281938 14626.332980705358 13909.89052394548 12937.202736163263 13077.548604907763 1.3175610947391925 1.0230448210690488 1.2324632331608907 1.2615773833630604 1.048028924259206 1.1072389881118754 1.1184307871902204 1.0636466316573547 0.989268182211777 1.0 13.674804511593964 -7.249352489678123 0.5178021518105796 0.9890102455972768 1.2045886639474224 0.4484396703754131 0.08168855235947692 0.9376113927288795 0.5379498709209947 0.07785649562791343 0.06823681612003962 5.631803719797732e-08 7.249352489678123 0.21557841835014557 VPSS(ph)DEEVVEEPQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VPSSDEEVVEEPQSR 15 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 VPS(0.032)S(0.968)DEEVVEEPQSR 207.4 5.6912e-13 7458700.0 3641.9 3939.1 5043.0 3822.2 3694.3 2753.8 3972.3 3886.5 3432.7 3405.8 True False 4258.401739196219 4330.147815395021 5163.244245684003 3608.054525739596 2970.4284347544476 2609.3858802121617 3596.0149870384726 3784.4834930871352 3482.8967434696237 4023.244579702033 1.0584496305992914 1.0762825201434105 1.2833533093497387 0.896802183974312 0.738316643671323 0.648577492250152 0.8938096891203164 0.9406545931063975 0.8656935153884111 1.0 11.97414372911276 -5.905599885780295 6.593260128035383 0.835561667399638 1.1312438820508421 0.5900867342009206 0.10888284636745818 0.15138536024323346 8.914565757948042 0.032493171855472194 0.04855349382041784 1.2427967652971548e-06 5.905599885780295 0.29568221465120414 VPSS(ph)DEEVVEEPQSR ddPTM_PC-9_Lapatinib_30min_R1 2 VPSSDEEVVEEPQSR 15 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 VPS(0.052)S(0.948)DEEVVEEPQSR;VPS(0.034)S(0.966)DEEVVEEPQSR 287.54 3.3134999999999995e-89 43859000.0 15123.9 18978.5 19172.0 12750.5 16848.2 17769.6 12483.8 13421.300000000001 17637.6 11502.9 True False 14908.230412616409 18934.55644928556 17595.752166060152 13688.214304421112 15857.222000835667 17009.635630960773 13130.150080297466 14044.902594864527 15651.06775583813 13491.160938349198 1.105036881610324 1.4034786580496033 1.3042429963194258 1.01460610891623 1.1753786107288098 1.2607985116099358 0.9732409345866194 1.0410447743560225 1.1600979209542528 1.0 13.71972687964689 -6.42371621345071 0.5610024416610179 1.0427544983138421 1.2836828317504512 0.27960381193629025 0.11595696909272717 1.3333030580248566 0.8885172068075959 0.09415623386651314 0.16076947018054033 3.769500337645204e-07 6.42371621345071 0.24092833343660902 VPSS(ph)QSMEDR ddPTM_PC-9_Lapatinib_30min_R1 1 VPSSQSMEDR 10 0 O95049-5;O95049;O95049-4;O95049-3 O95049-5 TJP3 Tight junction protein ZO-3 1 VPS(0.108)S(0.537)QS(0.355)MEDR 96.334 0.005571 3728600.0 8709.3 13125.0 9944.0 10894.0 9857.7 10947.0 12678.0 12734.0 9324.8 11957.0 True False 8585.103784909981 13094.609868897602 9126.442704950041 11695.181101318667 9277.889466983883 10478.822328703385 13334.404806069579 13325.668127752522 8274.542829502847 14023.751518298988 0.6121831076162216 0.9337451431459699 0.6507846843293922 0.8339552427221867 0.6615839887691654 0.7472196234388511 0.9508443435175024 0.9502213519944669 0.5900377526445583 1.0 13.7755847184026 -7.2268670315706105 20.920830021595595 0.8686275434080203 0.7453854492999212 0.18517669050875463 0.136136090255912 158.02709957656884 95626.46806993775 0.04957462482460103 0.038393784495377156 5.9310688898616057e-08 7.2268670315706105 -0.12324209410809905 VPT(ph)ANVSVVDLTCR ddPTM_PC-9_AZD4547_30min_R2 3 VPTANVSVVDLTCR 14 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 VPT(0.86)ANVS(0.14)VVDLTCR;VPT(0.993)ANVS(0.007)VVDLTCR;VPT(1)ANVSVVDLTCR 172.42 0.00044466 21427600.0 2684.0 3699.1 5382.0 10027.2 10710.6 6667.4 1409.5 3308.7 4497.3 6796.700000000001 True False 3537.4561693318788 4894.761735156901 5310.631163463669 7715.583958695689 9223.618068413538 6250.486423997553 1534.9427694366912 2797.4164413621525 4735.01809658008 6558.749601754474 0.5393491723461443 0.7462949544296592 0.8097017702952203 1.176380320515935 1.4063073952306715 0.9529997032247641 0.2340297865657338 0.4265167312705215 0.7219391475645689 1.0 12.679205081930116 -10.754769026774698 5.071784204620562 1.0000269526363306 0.7880231648782364 0.03889882180784954 0.32654655872976907 0.0001137928714396587 1.723332272591152e-05 0.36152361829710367 0.08767121822687052 1.7588587888100383e-11 10.754769026774698 -0.21200378775809414 VPT(ph)ANVSVVDLTCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VPTANVSVVDLTCR 14 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 VPT(1)ANVSVVDLTCR 135.57 0.00010211 3478300.0 1537.0 1590.4 1337.9 3457.0 3226.2 2491.2 1377.7 1552.9 2718.7 1141.9 True False 1797.1837428662475 1748.284401412566 1369.8006100140058 3263.315497745221 2594.049269470481 2360.55708649304 1247.194282315763 1512.1380204335567 2758.455844224915 1348.917430724573 1.3323156050410643 1.2960648009963607 1.0154814363086815 2.4192107118019273 1.9230600853582887 1.7499641065688234 0.9245890474154751 1.1210011717480064 2.044940469590645 1.0 10.397586326106206 -11.378505789898648 2.666765946740406 0.7827480527630152 1.5273309897335168 0.1071251784318017 0.46383648405213507 55077171.193066336 33653227.49528937 75901098.20939422 0.12592857475828906 4.183061118683746e-12 11.378505789898648 0.7445829369705016 VPT(ph)ANVSVVDLTCR ddPTM_PC-9_Lapatinib_30min_R1 3 VPTANVSVVDLTCR 14 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 VPT(1)ANVSVVDLTCR;VPT(1)ANVSVVDLTCR;VPT(1)ANVSVVDLTCR 146.3 0.00031519 17947500.0 6959.9 6798.3 9391.7 7843.9 11324.5 9111.7 6460.099999999999 8703.2 5033.0 4033.43 True False 6860.65054971066 6782.558954036306 8619.550679010395 8420.766572483339 10658.415174823636 8722.013831410124 6794.5723684879395 9107.582444593669 4466.130540160415 4730.603001292353 1.4502697748757187 1.4337620282622279 1.8220828669528222 1.7800619857939612 2.25307749813541 1.8437425057709045 1.436301538436375 1.925247678172438 0.9440932876718493 1.0 12.207808377640394 -8.26829232520661 24.94619078923155 0.9720464758654922 1.746755538147897 0.6178559529508494 0.24253343185105072 398.0829145744908 1449085.9012225447 0.23233858930790716 0.06528789781083058 5.391475981290875e-09 8.26829232520661 0.7747090622824048 VPT(ph)TPASPVK ddPTM_PC-9_Lapatinib_30min_R1 1 VPTTPASPVK 10 0 Q6IE81-2;Q6IE81 Q6IE81-2 JADE1 Protein Jade-1 1 VPT(0.659)T(0.048)PAS(0.293)PVK 101.3 0.0089417 14260000.0 19654.0 36828.0 32593.0 29169.0 40281.0 30728.0 40711.0 39583.0 23761.0 27207.0 True False 19373.73035589782 36742.72702870559 29913.32935261836 31314.18556493154 37911.75077549301 29413.835070466575 42818.81637954715 41422.17068484592 21084.7859655775 31909.693698951283 0.6071424733398347 1.1514597217808187 0.9374370570533388 0.9813377044719387 1.188095101543986 0.9217836857968106 1.3418748792613573 1.2981061828934843 0.660764285752779 1.0 14.961707139808013 -4.754875492280754 24.945620234792347 1.0659753347401717 0.6071416791139957 0.3274553459530326 0.19111560777675093 252.7839633249041 960598.2810508121 0.04649110654250671 0.4341391130190294 1.7584276646581748e-05 4.754875492280754 -0.45883365562617595 VPTANVS(ph)VVDLTCR ddPTM_PC-9_AZD4547_30min_R2 3 VPTANVSVVDLTCR 14 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 VPTANVS(1)VVDLTCR;VPT(0.037)ANVS(0.962)VVDLT(0.001)CR;VPTANVS(1)VVDLTCR 197.51 9.404600000000001e-08 33436000.0 8210.0 12356.2 13554.3 24033.9 17097.4 21351.3 6323.6 18702.5 9155.9 11842.3 True False 10820.609221391478 16350.100011339446 13374.561125777711 18493.255675053486 14723.721132606364 20016.19983572293 6886.388149563583 15812.458365695184 9639.862181859682 11427.704681515592 0.9468751182285892 1.4307422590107592 1.1703628592547701 1.6182826027143038 1.2884233136005088 1.7515503238458114 0.6026046648459839 1.383695046939038 0.8435519161999557 1.0 13.48024803882069 -7.2610123353556775 24.99999995932152 0.9894375121000187 1.36938728305861 0.34385651362022385 0.27620957928192313 47.699556560812105 2792538.766287582 0.1048418169750714 0.07610775106172551 5.4826139231837635e-08 7.2610123353556775 0.3799497709585913 VPTANVS(ph)VVDLTCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VPTANVSVVDLTCR 14 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 VPT(0.003)ANVS(0.997)VVDLTCR;VPT(0.02)ANVS(0.98)VVDLTCR;VPT(0.006)ANVS(0.994)VVDLTCR 165.16 0.00012222 18981500.0 6758.4 6166.4 4813.3 10212.1 7871.6 9382.400000000001 7417.4 6677.0 5654.4 7100.4 True False 7902.463635515447 6778.559439682121 4928.067326541905 9639.94914507491 6329.216486753403 8890.370427228767 6714.7701746744115 6501.735824866286 5737.084902926164 8387.646313264528 0.9421550862270152 0.8081599040439106 0.5875387614697678 1.1493032473043059 0.7545879082602888 1.0599362556774972 0.8005547592124183 0.7751561739774608 0.6839922296024011 1.0 13.034050312422606 -10.650412747689614 4.4704530698032645 1.0000160880283118 0.8417467643309006 0.08215857827188966 0.16020097029041158 33313535.453835748 79366208.98622742 3652.678705358649 0.03773336455997721 2.2365944985493547e-11 10.650412747689614 -0.1582693236974112 VPTANVS(ph)VVDLTCR ddPTM_PC-9_Lapatinib_30min_R1 2 VPTANVSVVDLTCR 14 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 VPTANVS(1)VVDLTCR;VPT(0.088)ANVS(0.912)VVDLTCR 181.81 2.6345e-05 15555200.0 8483.0 8505.3 5476.2 4830.2 8646.6 10870.599999999999 8318.0 8537.3 11754.2 4547.3 True False 8362.030864408322 8485.60650041407 5025.967974743305 5185.429021074846 8138.023987869662 10405.689778606285 8748.665339713416 8933.97412494594 10430.318218786719 5333.294746103619 1.5678921309416523 1.5910627303344627 0.9423758134528679 0.9722749759636291 1.5258905377046923 1.9510809497653283 1.640386619566636 1.6751322681861702 1.9556988157099073 1.0 12.380811345852242 -6.514945021158378 24.482987662827778 1.6921881543819988 1.2657762808669544 0.23256318760437567 0.3172346498912765 379.53476322841124 1171226.2552878256 0.1027298538059907 0.1073406218135569 3.055307870732741e-07 6.514945021158378 -0.4264118735150444 VPTANVSVVDLTCR ddPTM_PC-9_AZD4547_30min_R2 2 VPTANVSVVDLTCR 14 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 184.98 2.8455e-05 57382000.0 9445.1 8787.3 8373.8 11384.699999999999 15656.7 13775.2 9534.2 3654.7 8951.7 6410.3 False True 12448.445329715552 11627.62287998277 8262.757940656276 8760.133306861615 13483.03745931416 12913.834566375363 10382.725329807243 3089.950091651181 9424.868586742248 6185.877348143463 2.012397697062591 1.8797047250658003 1.3357455176727902 1.416150501188122 2.1796483668336486 2.087631849061981 1.6784563846749014 0.499516870081259 1.5236106466887658 1.0 12.594762513016613 -7.6193079717659 7.788902175194245 1.0127521753071551 1.8043289719735642 0.5325041612383907 0.3414428581976797 0.1941733415058317 13.754191034297227 0.16617856984327048 0.09540731195637525 2.4026583957305503e-08 7.6193079717659 0.7915767966664091 VPTANVSVVDLTCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VPTANVSVVDLTCR 14 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 107.93 0.0033821999999999997 46370000.0 4966.9 7281.9 5991.7 6062.9 8647.0 6328.3 15387.0 6070.4 8848.3 0.0 False True 5807.698069253325 8004.798907599456 6134.56485164879 5723.215369187009 6952.682423008881 5996.4328076645415 13929.43196776703 5911.058432120455 8977.689648161 0.0 0.0 VPTANVSVVDLTCR ddPTM_PC-9_Lapatinib_30min_R1 2 VPTANVSVVDLTCR 14 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 203.88 5.3571e-10 364290000.0 13945.0 13738.800000000001 8864.8 11925.0 10373.2 12639.5 12990.400000000001 8958.8 11573.8 11841.1 False True 13746.141742800191 13706.988652709353 8135.970363117573 12802.004280633839 9763.068770495873 12098.938049113582 13662.97934948464 9375.058553707335 10270.236766482925 13887.818357726019 0.9897984974114376 0.9869792576228457 0.585835021279019 0.9218153601146343 0.7029951371062193 0.8711906893844666 0.983810343536334 0.675056248016942 0.7395140476307732 1.0 13.76153236319609 -5.076850145024578 24.999999633251335 0.8056108521714435 0.9891131535468983 0.23242748264706026 0.12945716147705605 140.42050237126801 45679.05042603289 0.031632811925333036 0.08369264967178844 8.378183246802779e-06 5.076850145024578 0.18350230137545487 VPTTPAS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 1 VPTTPASPVK 10 0 Q6IE81-2;Q6IE81 Q6IE81-2 JADE1 Protein Jade-1 1 VPT(0.002)T(0.039)PAS(0.959)PVK 112.64 0.0014215 13026000.0 47877.0 53547.0 60980.0 51271.0 46142.0 68555.0 66218.0 68114.0 58135.0 56523.0 True False 63100.890096535935 70855.02058134321 60171.36535637585 39451.26307905363 39735.97976889603 64268.24501262153 72111.27371873645 57588.54640400807 61207.89741504523 54544.146974262214 1.1568773845947466 1.299039851421228 1.1031681434997773 0.7232904952692637 0.7285104263826195 1.1782794044418339 1.322071711063034 1.0558153275581048 1.1221716867976217 1.0 15.73513677162076 -5.516899658872632 24.838510236024124 1.0192905016216383 1.221245010437402 0.18214105130601932 0.17652448586362388 446.73274051914626 1855827.781395572 0.05412651600422779 0.09796793150746014 3.041587685037263e-06 5.516899658872632 0.2019545088157637 VPTTPAS(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VPTTPASPVK 10 0 Q6IE81-2;Q6IE81 Q6IE81-2 JADE1 Protein Jade-1 1 VPT(0.002)T(0.227)PAS(0.771)PVK;VPTT(0.04)PAS(0.96)PVK 96.334 0.005571 16713400.0 77286.0 106687.0 98248.0 95034.0 99916.0 67903.0 99293.0 79634.0 69463.0 72187.0 True False 90368.99333192004 117278.18029017994 100590.6049276147 89709.55308438509 80338.17705300743 64342.04714360033 89887.24822093273 77543.6918791974 70478.7649639149 85273.9316680223 1.0597493461862786 1.3753110475397399 1.1796172987451938 1.0520161476033612 0.9421188337576585 0.7545336058162377 1.0540999630563583 0.9093481485183621 0.8264983633954387 1.0 16.379817155076772 -5.957476142165987 2.2136224284358375 0.9086890260003867 1.2277076104439757 0.6039431342648456 0.1056634302337699 0.193936774596698 1.9197224592798907 0.03231658921634272 0.05195686124202639 1.1028688179453291e-06 5.957476142165987 0.319018584443589 VPTTPAS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 1 VPTTPASPVK 10 0 Q6IE81-2;Q6IE81 Q6IE81-2 JADE1 Protein Jade-1 1 VPTT(0.047)PAS(0.952)PVK 122.18 0.0005605 15147000.0 35009.0 74341.0 68208.0 62196.0 80565.0 70707.0 77236.0 78764.0 61988.0 60203.0 True False 34509.765240135675 74168.8679819973 62600.2015304941 66770.10131977384 75826.32509688422 67683.02643606736 81234.90216134948 82423.66298211885 55006.25867742172 70609.00833454495 0.4887445108509196 1.0504165081965995 0.8865752827726289 0.9456314837820352 1.073890242695658 0.9585607847002423 1.1504892092020202 1.1673250329702431 0.7790260757777886 1.0 16.10756463458278 -4.758507154469187 24.987480293315745 1.006819268575128 0.4887438057418052 0.6534349926866883 0.11192413160855985 49.568739653327995 422332.1741171566 0.02774061376396861 0.18909577268906655 1.743784630515141e-05 4.758507154469187 -0.5180754628333228 VPTTPAS(ph)PVKNWGGFR ddPTM_PC-9_AZD4547_30min_R2 2 VPTTPASPVKNWGGFR 16 1 Q6IE81-2;Q6IE81 Q6IE81-2 JADE1 Protein Jade-1 1 VPT(0.001)T(0.004)PAS(0.995)PVKNWGGFR;VPT(0.034)T(0.034)PAS(0.931)PVKNWGGFR 65.47 0.013402 11572100.0 32592.0 30441.0 47788.0 74391.0 71567.0 56160.0 40766.0 47733.0 38522.0 57428.0 True False 42955.57804428639 40280.45794380018 47154.29989587547 57241.30427949283 61631.157386341765 52648.306322059965 44394.09502579366 40356.96164522007 40558.19427577835 55417.46319972278 0.7751271091113617 0.7268549590339546 0.8508924294483288 1.0329109449343972 1.1121252007553113 0.950030970062941 0.8010849371758275 0.7282354571116845 0.7318666704321687 1.0 15.758053050799221 -10.210491746090725 6.681589319201958 0.9999999955236468 0.8626329628220759 0.09977852825323341 0.12808623374461423 6.279722369211413e-10 0.0 0.14343189388057923 0.034787343773285365 6.158972343333426e-11 10.210491746090725 -0.1373670327015709 VPTTPAS(ph)PVKNWGGFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VPTTPASPVKNWGGFR 16 1 Q6IE81-2;Q6IE81 Q6IE81-2 JADE1 Protein Jade-1 1 VPT(0.003)T(0.011)PAS(0.986)PVKNWGGFR 55.724 0.030402999999999996 3761300.0 14644.0 9411.8 13754.0 18851.0 21148.0 20141.0 21105.0 20294.0 20407.0 14552.0 True False 17122.939967816088 10346.141303580725 14081.947522335478 17794.8395857666 17004.20121218825 19084.770503795906 19105.781613032 19761.304003270383 20705.413768748975 17190.162406431373 0.9960894820522385 0.6018640812671969 0.819186415427174 1.0351757688518985 0.989182115337459 1.1102146711921523 1.1114369463946387 1.1495705238873757 1.204492039063135 1.0 14.069295554490283 -5.932439914821651 1.6790378878388377 1.1114597318319586 0.7766473123730777 0.5834700427010753 0.10824495703994826 0.23756050962062797 1.3596141711239875 0.03500450449794669 0.06253120313913006 1.16831535655403e-06 5.932439914821651 -0.33481241945888085 VPVAS(ph)PSAHNISSSGGAPDR ddPTM_PC-9_AZD4547_30min_R2 2 VPVASPSAHNISSSGGAPDR 20 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 VPVAS(0.926)PS(0.074)AHNISSSGGAPDR;VPVAS(0.953)PS(0.047)AHNISSSGGAPDR 103.94 9.3727e-05 22710000.0 11703.1 12825.4 42302.0 69454.0 51170.0 45721.0 23816.0 64554.0 32085.0 42387.0 True False 15424.442360397892 16970.959735633354 41741.04784036422 53442.45335360329 44065.92875849355 42862.05864228818 25935.577862294613 54578.66260334644 33780.94759717428 40903.04403159869 0.3770976641367351 0.41490701089441745 1.0204875658671797 1.3065642085786469 1.0773263898024668 1.0478941031668962 0.6340745163675028 1.3343423184148095 0.8258785720465596 1.0 15.319920593031252 -5.260050834526666 5.880247245283194 1.0420304753109093 0.38927020164701787 0.6342221960242201 0.19283271457513396 0.08789855759565605 13.412725134599993 0.04957453516435632 0.11975608437880512 5.494765534103507e-06 5.260050834526666 -0.6527602736638914 VPVAS(ph)PSAHNISSSGGAPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VPVASPSAHNISSSGGAPDR 20 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 VPVAS(0.976)PS(0.024)AHNISSSGGAPDR;VPVAS(0.943)PS(0.056)AHNISSSGGAPDR 89.62200000000001 0.00039056 14262800.0 22359.8 27970.0 40421.0 51567.0 52583.0 42809.0 42337.0 42021.0 36817.0 35248.0 True False 26144.87251381958 30746.67675270968 41384.78993749615 48677.86817246968 42279.73862022386 40564.02067906255 38326.53286666363 40917.99327492976 37355.37897407906 41638.183376985515 0.6279061763359858 0.7384250286409987 0.9939143973406529 1.169068009805999 1.0154078586337403 0.9742024600785855 0.9204660184057808 0.9827036137591482 0.897142380969635 1.0 15.34561950653968 -5.161861971518422 3.3782781659299337 0.9978973619061203 0.6489582179253965 0.7699522929123288 0.06905043987178758 0.12170614319969567 2.565191974745675 0.02003258699444688 0.06564234085026871 6.8887120020201364e-06 5.161861971518422 -0.3489391439807238 VPVASPS(ph)AHNISSSGGAPDR ddPTM_PC-9_AZD4547_30min_R2 4 VPVASPSAHNISSSGGAPDR 20 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 VPVAS(0.003)PS(0.997)AHNISSSGGAPDR;VPVASPS(1)AHNISSSGGAPDR;VPVAS(0.008)PS(0.992)AHNISSSGGAPDR;VPVAS(0.022)PS(0.978)AHNISSSGGAPDR 217.73 1.4824999999999998e-28 137806000.0 23882.199999999997 20133.399999999998 149254.7 266479.0 183527.0 195283.2 143819.0 251746.0 145231.5 245718.0 True False 31476.242819380688 26641.1278199043 147275.48515671157 205046.3836095091 158047.4439566163 183072.11063305012 156618.6123856795 212844.4402475768 152908.14059401635 237115.4876107382 0.13274646517841052 0.11235507257813475 0.6211128873980897 0.8647532292202038 0.6665420531959332 0.7720799365648833 0.6605161643544483 0.8976403962148348 0.6448677905217172 1.0 17.85523037247173 -5.339446898158293 3.403506011962318 0.7704447642968184 0.11024212144922851 0.8504836459445944 0.10944182618698775 0.07623224831531063 1.6925240291861456 0.027164997957773215 0.0668673956919699 4.576706915514489e-06 5.339446898158293 -0.6602026428475899 down VPVASPS(ph)AHNISSSGGAPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 VPVASPSAHNISSSGGAPDR 20 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 VPVASPS(1)AHNISSSGGAPDR;VPVASPS(1)AHNISSSGGAPDR;VPVASPS(1)AHNISSSGGAPDR;VPVAS(0.002)PS(0.998)AHNISSSGGAPDR;VPVAS(0.012)PS(0.988)AHNISSSGGAPDR 212.47 2.6849e-22 117335400.0 35384.94 65497.979999999996 163755.69999999998 153933.59999999998 191018.2 175532.3 155558.5 146988.19999999998 146935.9 100030.2 True False 41374.91145757812 72000.18659333009 167660.25693495054 145309.1994514648 153589.55494562228 166327.0771810461 140822.87273398935 143129.91549687105 149084.55956208755 118164.88342137227 0.35014557844597943 0.6093196600260644 1.4188670278383748 1.2297155909958186 1.2997901787617117 1.4075846593774308 1.191748924524551 1.2112728532594093 1.2616655240157661 1.0 16.85044182940142 -5.1338415886124915 4.033196701445829 1.2635486955665578 0.4020405365241959 0.8783306802350482 0.11636771913345245 0.06484614850006717 1.7575920606802689 0.028999180977255682 0.08953139419561679 7.347818351451132e-06 5.1338415886124915 -0.8615081590423619 down VPVASPS(ph)AHNISSSGGAPDR ddPTM_PC-9_Lapatinib_30min_R1 4 VPVASPSAHNISSSGGAPDR 20 0 E9PC69;Q7KZI7-14;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E7ETY4;Q7KZI7-11;Q7KZI7-8;Q7KZI7;Q7KZI7-12;Q7KZI7-3;Q7KZI7-6;Q7KZI7-5;Q7KZI7-4;Q7KZI7-9;Q7KZI7-10;Q7KZI7-7;Q7KZI7-2 E9PC69;Q7KZI7-11 MARK2 Serine/threonine-protein kinase MARK2 1 VPVAS(0.013)PS(0.987)AHNISSSGGAPDR;VPVAS(0.003)PS(0.997)AHNISSSGGAPDR;VPVAS(0.001)PS(0.999)AHNISSSGGAPDR;VPVAS(0.004)PS(0.996)AHNISSSGGAPDR 251.38 4.072e-55 76417000.0 44618.6 36068.2 72025.5 41487.5 57251.4 60030.4 31133.0 37032.2 62556.1 29057.0 True False 43982.330581950904 35984.68629892359 66103.84141647026 44538.62914824287 53883.98521258313 57463.039729697215 32744.914405061074 38752.8512046927 55510.37327306357 34079.46373398121 1.290581651321449 1.0559052976835035 1.9396972303457052 1.3069052229197096 1.5811277323256263 1.6861485901962667 0.9608400725041505 1.1371320718891351 1.628851137634341 1.0 15.056615013399204 -7.258751298360918 24.997874204101443 1.1931334982183104 1.4756696600860595 0.20788480780920848 0.2817680562478556 424.33554503983976 3946142.1744923624 0.11212423136791129 0.0828360076708843 5.511232104478555e-08 7.258751298360918 0.2825361618677491 VPVDVAYQR ddPTM_PC-9_Lapatinib_30min_R1 1 VPVDVAYQR 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4;A0A075B730;P58107 Q15149;Q15149-3;Q15149-4;A0A075B730 PLEC;EPPK1 Plectin;Epiplakin 0 93.14299999999999 0.029874 2291000.0 6072.8 8424.1 11119.0 7333.9 7642.7 10042.0 6163.4 6762.9 6328.8 7989.3 False True 5986.200758384875 8404.594514025162 10204.838740581214 7873.259471173209 7193.1714121263285 9612.527069045342 6482.510694252189 7077.129023180264 5615.983898781489 9370.239859926915 0.6388524571271291 0.8969455040279743 1.089069105287643 0.8402409744967423 0.7676613960426871 1.0258570978694581 0.6918190773296545 0.7552772531946118 0.5993425977064895 1.0 13.193870263208021 -7.290919241033239 24.961853796254132 0.7412161621553072 0.880445335399536 0.11616507388581765 0.15079105870112555 1321.9252286271246 1119324.9638179222 0.062136491140895894 0.04189926134956282 5.117769938727198e-08 7.290919241033239 0.1392291732442288 VPVHDVTDASK ddPTM_PC-9_AZD4547_30min_R2 1 VPVHDVTDASK 11 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 107.11 0.0019722000000000003 6849000.0 56075.0 44773.0 55973.0 69109.0 60638.0 58798.0 61498.0 70623.0 52526.0 54365.0 False True 73905.68356754299 59244.99666626475 55230.7614478915 53176.98777340638 52219.4603880698 55121.35176503712 66971.20286258782 59709.83810509236 55302.417126045715 52461.69789741814 1.4087550828426427 1.1293000234592188 1.0527825758878009 1.0136345163167781 0.9953825835026917 1.0506970604119519 1.2765733010308031 1.1381606104676023 1.0541484424347496 1.0 15.678976880033503 -4.764129149534838 3.506321434493446 1.0795556524302063 1.4555149862673138 0.6170494485363338 0.0789008313156334 0.2316839139590249 4.594286321602615 0.02200702949068891 0.23885911088836947 1.7213566056360913e-05 4.764129149534838 0.37595933383710745 VPVHDVTDASK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VPVHDVTDASK 11 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 146.71 0.00019912 10311800.0 93473.0 85071.0 101842.0 107486.0 107912.0 96068.0 109810.0 103235.0 89214.0 76030.0 False True 109296.13272409663 93516.28666534752 104270.29951793561 101463.90789431383 86767.41825277368 91030.02496195135 99408.00184444673 100525.19063652414 90518.5859736939 89813.63714685132 1.2169213517696664 1.0412259166438402 1.1609628874894207 1.1297160555742056 0.9660828912974889 1.013543464597822 1.1068252550768873 1.1192642212246533 1.0078490176908206 1.0 16.45464689746027 -1.522878745320478 0.5071838139027605 1.0487109071546188 5.614151272928161 0.3501290586978185 0.06264988645507348 150.50419765009818 1.567539930086579 0.035597733091615506 734.6838823587141 0.0299999999972272 1.522878745320478 4.565440365773542 VPVHDVTDASK ddPTM_PC-9_Lapatinib_30min_R1 3 VPVHDVTDASK 11 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ;; 133.89 4.7186000000000005e-05 27864000.0 231941.0 268770.0 305071.0 249904.0 294388.0 273001.0 315794.0 252634.0 275631.0 257702.0 False True 228633.4788072303 268147.67957817897 279989.23998811515 268282.7738153056 277072.6766290768 261325.38362641376 332144.2681280911 264372.29792576004 244586.53425689554 302245.44733366877 0.7564497027967693 0.8871851733209168 0.9263637962394732 0.8876321419628548 0.9167141443265412 0.8646131345625179 1.0989223197840763 0.8746940615912799 0.8092314918705137 1.0 18.205361083030795 -4.730808447996401 2.5298450678289166 0.9206418185776618 0.7070553795694507 0.3021247196009811 0.07544095722620342 0.8143928003255916 5.890589788499769 0.0196274910528902 0.3996922570302744 1.8586240479533535e-05 4.730808447996401 -0.21358643900821106 VPVLIS(ph)PTLK ddPTM_PC-9_AZD4547_30min_R2 1 VPVLISPTLK 10 0 P42684-2;P42684-6;P42684-3;P42684;P42684-4;P42684-7;P42684-10;P42684-5 P42684-2 ABL2 Abelson tyrosine-protein kinase 2 1 VPVLIS(0.988)PT(0.012)LK 102.4 0.0032306999999999995 11515000.0 76279.0 83208.0 105410.0 120630.0 112070.0 107480.0 109120.0 125230.0 112470.0 96011.0 True False 100534.13529823662 110103.35877887488 104012.1945263295 92820.61721492145 96511.01496901269 100759.25860924151 118831.46860654987 105878.58099911825 118414.9345879441 92649.6841134739 1.0850996013662189 1.1883835312813844 1.122639494366103 1.0018449399270288 1.041676675883855 1.087529434917828 1.2825890313992814 1.1427840473739996 1.2780932360537125 1.0 16.499498436981682 -7.195172168072764 23.457699545935416 1.1877653211180592 1.0880027504944287 0.19314110622575265 0.08676619902372759 148.90650138085292 52710.34108913948 0.032541365284967094 0.025206422501897634 6.380105084988407e-08 7.195172168072764 -0.09976257062363048 VPVPGPGS(ph)GGNGPER ddPTM_PC-9_AZD4547_30min_R2 4 VPVPGPGSGGNGPER 15 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 VPVPGPGS(1)GGNGPER;VPVPGPGS(1)GGNGPER;VPVPGPGS(1)GGNGPER;VPVPGPGS(1)GGNGPER 133.87 6.7725e-06 286556000.0 70834.8 95268.7 96370.6 74880.0 100845.1 95284.0 83272.0 117924.0 101195.5 83620.2 True False 93358.79294463126 126062.44419403166 95092.66287656862 57617.57288446762 86844.49857813482 89325.8764172216 90683.0466807606 99701.55542394018 106544.4875352922 80692.6822500079 1.1569672780907234 1.5622537345264578 1.1784546036274475 0.714037150307542 1.076237598708975 1.1069885636031496 1.1238075641084755 1.2355712146863282 1.3203736022206867 1.0 16.300150225787178 -5.5114214984850705 24.969086293633403 1.083313233640862 1.3622964690126127 0.2819164561152978 0.1752368092325675 662.6809284428144 1444196.0352343866 0.04843155913362043 0.09229951951834243 3.080197056572813e-06 5.5114214984850705 0.27898323537175074 VPVPGPGS(ph)GGNGPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 VPVPGPGSGGNGPER 15 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 VPVPGPGS(1)GGNGPER;VPVPGPGS(1)GGNGPER;VPVPGPGS(1)GGNGPER;VPVPGPGS(1)GGNGPER;VPVPGPGS(1)GGNGPER;VPVPGPGS(1)GGNGPER 146.27 2.1878000000000003e-05 279412600.0 91623.09999999999 114920.6 128457.3 104433.8 121472.0 72381.0 116859.3 76660.3 76931.5 71564.6 True False 107133.08119128748 126329.15768421364 131520.2092090229 98582.71276494802 97670.4335940481 68585.21294053177 105789.54111593422 74648.04835330189 78056.4776474011 84538.69547493808 1.2672667893609455 1.4943353097004501 1.5557397529041919 1.166125313516026 1.1553340520022926 0.8112878079703063 1.2513741845862296 0.8830044979275989 0.9233224762800052 1.0 16.367324229718506 -6.097228088672451 2.0636951520480604 0.9909963351161613 1.4410739179950127 0.6571601884361906 0.13947273182816175 0.19095998762955393 1.6081236501307616 0.044673338540001446 0.06537165279585519 7.994142974827311e-07 6.097228088672451 0.45007758287885147 VPVPGPGS(ph)GGNGPER ddPTM_PC-9_Lapatinib_30min_R1 4 VPVPGPGSGGNGPER 15 0 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 VPVPGPGS(1)GGNGPER;VPVPGPGS(1)GGNGPER;VPVPGPGS(1)GGNGPER;VPVPGPGS(1)GGNGPER 130.47 1.2242e-05 284273000.0 47564.9 92946.0 98153.0 85067.0 105044.0 95582.0 88013.4 88016.0 94588.0 79644.2 True False 46886.61580366563 92730.78924758537 90083.23922153696 91323.11095519335 98865.51844444996 91494.18067252464 92570.30319912628 92105.54467820517 83934.50338420297 93410.59385077444 0.5019410954454274 0.9927224035822417 0.9643792583681353 0.9776526108064799 1.0583972798887231 0.9794839846397796 0.9910043324101917 0.9860288954521141 0.8985544350386023 1.0 16.51129855720675 -4.760841814273074 24.999999999781487 0.9844255288203254 0.5019405445915791 0.9384154772081773 0.03697982026501408 3.1840187647708973 133099.03156482492 0.009258788127538506 0.05348763305373776 1.734435626778862e-05 4.760841814273074 -0.4824849842287463 VPVPGPGS(ph)GGNGPEREGPEEPGLAK ddPTM_PC-9_AZD4547_30min_R2 1 VPVPGPGSGGNGPEREGPEEPGLAK 25 1 Q6ZRV2;A0A494C1T9;J3KPS2 Q6ZRV2 FAM83H Protein FAM83H 1 VPVPGPGS(1)GGNGPEREGPEEPGLAK 43.604 0.028074 23995000.0 33800.0 19354.0 51639.0 94255.0 78433.0 51608.0 41603.0 45645.0 31924.0 62436.0 True False 44547.696916325454 25609.802011902015 50954.233119676814 72525.96597523364 67543.93180212872 48380.943601653715 45305.58640430983 38591.614067753355 33611.43746586231 60250.134644039346 0.7393792093497443 0.42505800465353216 0.8457115228159545 1.203747782535599 1.1210586034567636 0.8030014187933459 0.7519582598773826 0.640523283404335 0.5578649353140915 1.0 15.878676844959614 -13.023309122453128 9.46780325087829 0.9904803857107577 0.807110325024499 0.0 0.2319624739206727 0.0 0.0 0.0 0.058828588960742105 9.477436374859248e-14 13.023309122453128 -0.18337006068625872 VQAEDEANGLQTT(ph)PASR ddPTM_PC-9_Lapatinib_30min_R1 1 VQAEDEANGLQTTPASR 17 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 VQAEDEANGLQT(0.038)T(0.494)PAS(0.469)R 102.69 0.0022951 5337800.0 33461.0 31169.0 32412.0 30637.0 25616.0 27786.0 23938.0 26900.0 27931.0 16352.0 True False 32983.84000400413 31096.830095517635 29747.210473938136 32890.14718203597 24109.317242993693 26597.657552329598 25177.39251046645 28149.872203278046 24785.116653530804 19178.421412329597 1.7198412369226166 1.6214488891940722 1.5510771107998482 1.7149559119027 1.257106449204108 1.3868533275231014 1.3127979602262874 1.4677888027416481 1.2923439380467845 1.0 14.227196355675614 -1.5228787453462649 0.06473559549883366 0.4415847455793507 3.6430182426064475 0.7652688854072807 0.10472494825891994 145.74834591997103 0.7038427881153764 6.581301376955202 43.21830576101308 0.029999999995445902 1.5228787453462649 3.2014334970270966 VQAEDEANGLQTTPAS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 VQAEDEANGLQTTPASR 17 0 J3KP58;P30622-2;P30622-1;P30622;F5H1T5;F5H6A0 J3KP58 CLIP1 CAP-Gly domain-containing linker protein 1 1 VQAEDEANGLQTTPAS(1)R 138.28 6.8094e-05 5057000.0 10193.0 8477.5 13023.0 16002.0 10728.0 13644.0 14305.0 13092.0 9733.2 12036.0 True False 13434.161972429158 11217.686088451965 12850.306510922963 12312.986128435503 9238.602378759406 12790.838523115859 15578.117287543018 11068.932224231054 10247.677081278374 11614.623303473285 1.156659292463816 0.9658243573941293 1.106390295678393 1.0601278928050448 0.7954284988301477 1.101270199550151 1.3412503256032826 0.9530168938773033 0.8823081742318639 1.0 13.503654743595103 -3.085796482146377 0.00956192327412029 0.1322775503954384 2.0231056253257775 0.02906520984309069 0.14351652472125706 65801.187669505 64.44657066274223 5721.883836475051 7085.523696877585 0.0008207360652432918 3.085796482146377 1.8908280749303392 VQAGPGS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 3 VQAGPGSPR 9 0 Q6PK04;I3L0U5;I3L4F6 Q6PK04 CCDC137 Coiled-coil domain-containing protein 137 1 VQAGPGS(1)PR;VQAGPGS(1)PR;VQAGPGS(1)PR 95.618 0.005368199999999999 238411000.0 144527.0 157041.0 217969.0 277118.0 216009.0 206247.0 180166.0 227685.0 176676.0 211709.0 True False 190483.57965165004 207801.43214586648 215078.58864158526 213232.7265304203 186019.87893674886 193350.34248586 196200.42497221052 192501.51493080132 186014.7326687974 204297.13234920395 0.9323849897513858 1.017152956364912 1.0527734098291337 1.0437382261731545 0.9105359277328774 0.9464173102310968 0.9603679832218409 0.942262442537664 0.9105107376193781 1.0 17.640309428020345 -6.259719083462924 24.9855154417971 0.9429665467725797 1.0148625084778027 0.4167845316228156 0.03840831453553467 145.14466116233757 2108076.1964458786 0.011763267727051486 0.014423052178785891 5.498964506932118e-07 6.259719083462924 0.07189596170522294 VQAGPGS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VQAGPGSPR 9 0 Q6PK04;I3L0U5;I3L4F6 Q6PK04 CCDC137 Coiled-coil domain-containing protein 137 1 VQAGPGS(1)PR;VQAGPGS(1)PR 89.561 0.0092508 134685000.0 78117.0 69076.0 82964.0 95980.0 111360.0 107502.0 104708.0 101567.0 99130.0 80587.0 True False 91340.66521892157 75933.4087726197 84942.17640272228 90602.5517713585 89539.80740444879 101864.40587354476 94789.30021972761 98900.97386913188 100579.58871446481 95196.78517365894 0.9594931704079818 0.797646775929473 0.8922798836932351 0.9517396160603576 0.9405759579077105 1.0700403977689235 0.9957195513148055 1.0389108591084848 1.0565439634435818 1.0 16.538625233625396 -6.267391316941698 1.3361459845501293 1.0326026554250816 0.8746374238675677 0.6429762519852935 0.04661492389286907 0.25025730388702333 0.9049340589402819 0.017579114356997515 0.024725445540166244 5.402673008157515e-07 6.267391316941698 -0.15796523155751385 VQAGPGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 VQAGPGSPR 9 0 Q6PK04;I3L0U5;I3L4F6 Q6PK04 CCDC137 Coiled-coil domain-containing protein 137 1 VQAGPGS(1)PR;VQAGPGS(1)PR;VQAGPGS(1)PR 84.31 0.013306 213274000.0 377415.0 317356.0 418533.0 293951.0 317248.0 291724.0 252110.0 253302.0 303259.0 215863.0 True False 372032.9928905663 316621.18168029375 384122.83232409996 315569.13713179034 298588.09637356567 279247.64456185856 265163.0222162962 265071.3356444144 269102.77796115744 253174.63193063284 1.4694718426311344 1.250603898446842 1.5172248080105655 1.2464484878494972 1.1793760460778537 1.1029843015171024 1.0473522571919767 1.046990109645113 1.0629136731001103 1.0 17.94977332856567 -6.335687704496306 1.3246126200239037 1.0450991438551216 1.4001243744168055 0.819638693862177 0.07266054046026438 0.17124016717025572 0.6114736673500174 0.027782405674663564 0.036779820906605525 4.616494213169708e-07 6.335687704496306 0.3550252305616839 VQAGPGS(ph)PRR ddPTM_PC-9_AZD4547_30min_R2 4 VQAGPGSPRR 10 1 Q6PK04;I3L0U5;I3L4F6 Q6PK04 CCDC137 Coiled-coil domain-containing protein 137 1 VQAGPGS(1)PRR;VQAGPGS(1)PRR;VQAGPGS(1)PRR;VQAGPGS(1)PRR 91.62 0.0036466999999999997 21817900.0 44118.4 34943.7 55126.0 94560.0 68214.0 44512.2 42626.0 52156.0 41416.0 55967.0 True False 58147.1334802726 46238.56766370257 54394.99322131148 72760.65293743653 58743.663559348846 41728.84509737889 46419.63142249625 44096.48862564886 43605.16520756021 54007.61236502897 1.07664699352501 0.8561490804515363 1.007172708426069 1.3472295802609957 1.0876922897888848 0.772647470792454 0.8595016404123413 0.8164865413343516 0.8073892419616655 1.0 15.72087514881189 -6.753225979902492 24.90497342893144 0.8402539252349779 1.0741791174034105 0.4395084171431527 0.12604647282953502 175.0236987498499 530712.4728868998 0.0450676551930466 0.04433219057561059 1.7651191232157684e-07 6.753225979902492 0.23392519216843266 VQAGPGS(ph)PRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VQAGPGSPRR 10 1 Q6PK04;I3L0U5;I3L4F6 Q6PK04 CCDC137 Coiled-coil domain-containing protein 137 1 VQAGPGS(1)PRR;VQAGPGS(1)PRR;VQAGPGS(1)PRR 78.529 0.0092929 10940800.0 24740.199999999997 14433.5 25213.100000000002 34566.0 34423.3 33494.6 31151.800000000003 38263.0 33104.3 24318.6 True False 28928.22721877654 15866.362492321598 25814.275925214217 32629.37908448401 27678.30147472667 31738.08421212659 28200.87598449893 37258.636792999634 33588.3877603174 28727.369674068304 1.0069918529606818 0.5523082228667766 0.898595180070256 1.1358289831156376 0.9634819264261215 1.1048030004910614 0.9816727498708442 1.29697348611183 1.169212083855942 1.0 14.810138282900239 -5.590295984372643 4.540379174509712 1.0945998833336763 0.7668364189646119 0.46252864760838 0.1386131124386639 0.15993105728984192 6.422783849725721 0.03721068401759007 0.06770157204086436 2.5686445797923043e-06 5.590295984372643 -0.32776346436906445 VQAGPGS(ph)PRR ddPTM_PC-9_Lapatinib_30min_R1 3 VQAGPGSPRR 10 1 Q6PK04;I3L0U5;I3L4F6 Q6PK04 CCDC137 Coiled-coil domain-containing protein 137 1 VQAGPGS(1)PRR;VQAGPGS(1)PRR;VQAGPGS(1)PRR 81.278 0.007566 16692100.0 73039.0 34833.6 43153.8 36215.6 31451.3 35972.3 24131.3 26871.1 40361.4 27564.8 True False 71997.45046628788 34752.944939370005 39605.861142485264 38879.016035700006 29601.3963696349 34433.848584526946 25380.70063864227 28119.629403773408 35815.47410761581 32329.338952212758 2.227000390348534 1.0749661473356964 1.2250748832516563 1.2025923602449335 0.9156202177034879 1.0650959685697547 0.7850671081199173 0.8697867112389188 1.1078319343478085 1.0 14.98055638809249 -2.787563161121837 1.273075238528968 0.9930581523022863 199.99999959191877 0.8657888185170359 0.14055590169126922 83.30562654662253 1.0970929593985375 0.04263110236973061 47473.664486447924 0.0016309356987088766 2.787563161121837 199.00694143961647 up VQAQGPGLK ddPTM_PC-9_Lapatinib_30min_R1 2 VQAQGPGLK 9 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 116.37 0.0008644999999999999 14585000.0 98916.0 97093.0 95993.0 105885.0 100886.0 89881.0 95396.0 80172.0 81553.0 95388.0 False True 97505.43970102732 96868.18712387623 88100.82608369584 113672.13612200551 94952.08382950733 86036.99915284452 100335.13810378712 83897.08380227546 72367.64234883805 111875.68870347935 0.8715516376346999 0.8658555602783397 0.7874885697213669 1.0160575317063527 0.8487284854279008 0.7690410682599781 0.896844875473528 0.7499134510326035 0.646857625526174 1.0 16.77153703802967 -6.527805204941523 23.520285436136422 0.8029165700582777 0.8838118669981181 0.09860204371178327 0.10159503675885977 143.43376376486341 684777.3617551613 0.03289979073463281 0.033037763948811354 2.9661615101423664e-07 6.527805204941523 0.08089529693984043 VQAYEEPS(ph)VASSPNGKESDLR ddPTM_PC-9_AZD4547_30min_R2 1 VQAYEEPSVASSPNGKESDLR 21 1 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 VQAY(0.003)EEPS(0.657)VAS(0.087)S(0.087)PNGKES(0.166)DLR 46.92 0.030374 23385000.0 15471.0 8311.9 18597.0 37216.0 39794.0 17836.0 14668.0 15340.0 16682.0 20053.0 True False 20390.456183209215 10998.559126936463 18350.391628936064 28636.426181468276 34269.28999443995 16720.712100432007 15973.423584318843 12969.555478132015 17563.776463022008 19350.950573658174 1.0537185811929097 0.568373067001083 0.948294067471593 1.4798459679004152 1.7709357410632647 0.8640770403906346 0.8254593759369605 0.6702283398825406 0.907644117851813 1.0 14.240116816938198 -6.964509211305566 24.99999273543559 0.8264099400245395 1.1547513923141515 0.201982941053376 0.3071103266855617 321.7399587243334 226635.32155452948 0.12280225670548829 0.10830107320590421 1.0851525335043407e-07 6.964509211305566 0.328341452289612 VQAYEEPS(ph)VASSPNGKESDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VQAYEEPSVASSPNGKESDLR 21 1 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 VQAYEEPS(0.698)VAS(0.149)S(0.149)PNGKES(0.003)DLR;VQAYEEPS(0.705)VAS(0.207)S(0.088)PNGKESDLR 63.376000000000005 0.0027194000000000003 12699400.0 24040.0 7200.700000000001 9810.599999999999 26953.0 32813.0 47079.0 25095.0 33229.0 33542.0 26709.0 True False 28109.49718835692 7915.537908231561 10044.521910907692 25442.910792804993 26383.528200091394 44610.09436215713 22717.819927933568 32356.773959035774 34032.48829477035 31551.130271672326 0.8909188655467781 0.25087969401015087 0.31835695977985307 0.8064025147032055 0.836214993659971 1.413898455555793 0.7200318889472684 1.0255345428333762 1.0786456143324246 1.0 14.945404068057705 -6.061500988857667 2.490041358711434 1.023204039025848 0.4686943714651935 0.5004498373530359 0.2326276577951274 0.22846669176449316 2.802766436283857 0.07194375077374457 0.10462521040413908 8.679586010100841e-07 6.061500988857667 -0.5545096675606545 VQAYEEPS(ph)VASSPNGKESDLR ddPTM_PC-9_Lapatinib_30min_R1 1 VQAYEEPSVASSPNGKESDLR 21 1 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 VQAY(0.002)EEPS(0.332)VAS(0.332)S(0.332)PNGKES(0.002)DLR 66.613 0.0018584 22453000.0 35306.0 22705.0 31925.0 28190.0 27485.0 26226.0 21739.0 22014.0 31076.0 23111.0 True False 34802.52996567258 22652.427967491043 29300.249734063782 30263.186639083277 25868.386337589072 25104.375115791976 22864.53905025607 23036.850806058108 27575.893635212597 27105.705556528195 1.2839558775953228 0.8357070034664855 1.0809624443443808 1.11648769208277 0.9543520748294587 0.9261657130982073 0.8435323331677425 0.8498893621498026 1.0173464615301688 1.0 14.726308940048336 -6.436923495639803 4.493932272275136 0.9148739162912423 1.061445584807533 0.27792618145599535 0.11456177784299638 0.31067362927805864 11.075874926032661 0.035573739071534514 0.039966171379126086 3.6565919965988834e-07 6.436923495639803 0.14657166851629078 VQAYEEPSVAS(ph)SPNGK ddPTM_PC-9_AZD4547_30min_R2 5 VQAYEEPSVASSPNGK 16 0 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 VQAYEEPS(0.022)VAS(0.489)S(0.489)PNGK;VQAYEEPSVAS(0.935)S(0.065)PNGK;VQAYEEPSVAS(0.746)S(0.254)PNGK;VQAYEEPSVAS(0.746)S(0.254)PNGK;VQAYEEPSVAS(0.715)S(0.285)PNGK 234.36 6.3120000000000005e-37 464059500.0 1581892.0 1567717.0 1854526.0 2034527.0 1999490.0 2033271.0 1680698.0 2045362.0 1776266.0 1916469.0 True False 2084900.7506023692 2074450.8618731536 1829933.7735142368 1565498.2332788073 1721895.3272096948 1906130.2429444664 1830276.8660565536 1729298.300642961 1870155.7944410914 1849374.003637766 1.127354848992857 1.1217043484944935 0.9894882105592001 0.8465016974389346 0.9310692828074162 1.030689432854068 0.9896737287624635 0.9350722445764821 1.0112372028386076 1.0 20.818605583482274 -5.29718840487304 4.3942965337771405 0.9605818275640716 1.1270161683036362 0.6198856858159592 0.04963602111213772 0.1277481545035811 5.824504320495725 0.013984471616544588 0.03304398756260403 5.044424137628386e-06 5.29718840487304 0.16643434073956453 VQAYEEPSVAS(ph)SPNGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VQAYEEPSVASSPNGK 16 0 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 VQAYEEPSVAS(0.902)S(0.098)PNGK;VQAYEEPSVAS(0.968)S(0.032)PNGK;VQAYEEPSVAS(0.571)S(0.429)PNGK 235.78 5.2342e-37 166864000.0 191105.0 176899.0 190072.0 199638.0 213457.0 172729.0 208121.0 181977.0 189841.0 143443.0 True False 223455.30200419907 194460.36363523715 194604.03733207454 188452.93009512854 171631.63316389543 163670.78716797382 188406.27221444336 177200.296570569 192617.06548111286 169448.08040583695 1.3187243046307282 1.1476103073548811 1.14845819950269 1.1121573619705456 1.0128862643520584 0.9659052305341777 1.1118820098947155 1.0457498022176768 1.1367320598721744 1.0 17.370483767767034 -3.414215778105441 0.68361401698854 1.0504870756177198 2.801004384162554 0.6982989098857879 0.05285789120274167 9.857470210334048 0.8104861246028876 0.0222436570436603 20.388354889777684 0.00038528688129833876 3.414215778105441 1.7505173085448342 VQAYEEPSVAS(ph)SPNGK ddPTM_PC-9_Lapatinib_30min_R1 5 VQAYEEPSVASSPNGK 16 0 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 VQAYEEPSVAS(0.986)S(0.014)PNGK;VQAYEEPSVAS(0.996)S(0.004)PNGK;VQAYEEPS(0.074)VAS(0.789)S(0.138)PNGK;VQAYEEPSVAS(0.5)S(0.5)PNGK;VQAYEEPSVAS(0.5)S(0.5)PNGK 276.14 2.3562999999999995e-82 537664000.0 959744.0 946175.0 1136817.0 967982.0 1131356.0 1036076.0 962912.0 996149.0 1078599.0 825200.0 True False 946057.8745645052 943984.1899203165 1043352.294500525 1039170.6253732895 1064811.8644114751 991765.444691119 1012766.8717953996 1042433.7191607126 957115.8224690014 967834.7204901153 0.977499416517541 0.9753568144799343 1.0780273453841036 1.0737067015399586 1.100200108415464 1.024726044327987 1.0464254385113714 1.0770782418642926 0.9889248672379868 1.0 19.8844011703992 -5.250087692742841 24.48921607549271 1.0531929560269286 0.9764280960811752 0.41268544801062723 0.0341116964668168 496.5549286995858 1071219.9242403747 0.00853169353891443 0.022148569401116567 5.622277886916318e-06 5.250087692742841 -0.07676485994575344 VQAYEEPSVAS(ph)SPNGKESDLR ddPTM_PC-9_AZD4547_30min_R2 1 VQAYEEPSVASSPNGKESDLR 21 1 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 VQAYEEPS(0.213)VAS(0.393)S(0.393)PNGKESDLR 76.237 0.00063854 20269000.0 21232.0 14083.0 21853.0 39906.0 25987.0 21080.0 18831.0 18301.0 17656.0 21005.0 True False 27983.334346965145 18635.054341924966 21563.214941503466 30706.28824155398 22379.153618271877 19761.864267610843 20506.922519519223 15473.000965143037 18589.260114561603 20269.62134342441 1.380555357835686 0.919358779633557 1.0638193272662544 1.5148920505865933 1.104073590675724 0.9749498489778998 1.0117072328128023 0.763359152249905 0.9170995254231562 1.0 14.307031517635645 -6.760016117057547 2.9285572985311763 0.9143894305642062 1.1979098023393675 0.3990267964188631 0.16495232238852264 0.2881196602163818 5.084206456027832 0.0630347748822413 0.058628248849828486 1.7377363385994189e-07 6.760016117057547 0.2835203717751613 VQAYEEPSVAS(ph)SPNGKESDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VQAYEEPSVASSPNGKESDLR 21 1 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 VQAYEEPS(0.005)VAS(0.497)S(0.497)PNGKES(0.002)DLR 81.329 0.0024952 0.0 9064.2 6565.4 5821.1 14171.0 16770.0 24647.0 13021.0 22773.0 18222.0 14984.0 True False 10598.590033889554 7217.169522782992 5959.897100644689 13377.044813001874 13484.03888445228 23354.467931436255 11787.55661612365 22175.232879988 18488.462277362858 17700.480586721253 0.5987741396039 0.40773861971845277 0.33670820808762403 0.7557447238487535 0.7617894225181597 1.3194256402821387 0.6659455690127742 1.252803999944706 1.0445175308535262 1.0 14.111500911081842 -6.205827490184374 1.7948674639047364 1.0436977354569996 0.450051754325567 0.6399041659660869 0.19004206386632838 0.2128963561433464 1.353130167820504 0.06321906021456716 0.08740231753170498 6.2254752347413e-07 6.205827490184374 -0.5936459811314326 VQAYEEPSVAS(ph)SPNGKESDLR ddPTM_PC-9_Lapatinib_30min_R1 1 VQAYEEPSVASSPNGKESDLR 21 1 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 VQAYEEPS(0.04)VAS(0.48)S(0.48)PNGKESDLR 85.913 0.00021494 17829000.0 28684.0 13622.0 18064.0 19477.0 20398.0 18881.0 17404.0 11653.0 20458.0 12962.0 True False 28274.960899998634 13590.459095933189 16578.847649056483 20909.403553367316 19198.22974401098 18073.503643760716 18305.093961573974 12194.440921367992 18153.80460770947 15202.464429220665 1.859893245048567 0.8939642095008596 1.0905368485645177 1.3753956571131547 1.2628366823940764 1.1888535393657376 1.2040872745862008 0.8021357970046653 1.1941356411146098 1.0 13.892017593456474 -4.750216659931143 24.991633158374114 1.1237400918105949 1.8598948469530454 0.6492934798486697 0.16461162991227127 332.4337588801772 740242.2443476795 0.042784309482463256 0.6446188952854142 1.777392486943547e-05 4.750216659931143 0.7361547551424505 VQAYEEPSVASS(ph)PNGK ddPTM_PC-9_AZD4547_30min_R2 1 VQAYEEPSVASSPNGK 16 0 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 VQAYEEPSVAS(0.233)S(0.767)PNGK 147.75 3.0193e-05 11580000.0 39851.0 41043.0 49601.0 56337.0 53167.0 53007.0 43800.0 51823.0 48284.0 56957.0 True False 52522.78904770669 54309.34711039033 48943.25833128234 43349.37504797339 45785.67977922273 49692.46391049561 47698.115148156896 43814.94612407016 50836.19366626036 54962.952766361515 0.9556034820576769 0.9881082506838823 0.8904772372643823 0.7887017139025349 0.8330280211445359 0.904108338606372 0.8678230107271301 0.7971723482601143 0.9249174417967803 1.0 15.746171891473958 -5.372315262879982 4.660351900629569 0.8630544621024676 0.971124283878474 0.28196584924679935 0.059806535372752156 0.22975895123195025 7.79893431063135 0.015174916411399385 0.03315402545646475 4.243114361305222e-06 5.372315262879982 0.10806982177600644 VQAYEEPSVASS(ph)PNGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VQAYEEPSVASSPNGK 16 0 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 VQAYEEPSVAS(0.18)S(0.82)PNGK;VQAYEEPS(0.001)VAS(0.1)S(0.899)PNGK 292.38 1.6667999999999997e-111 161697000.0 287245.0 294253.0 279340.0 314282.0 360460.0 262489.0 310174.0 279120.0 259500.0 236808.0 True False 335869.9051526444 323464.4931896709 286000.52500284894 296673.7984559915 289830.4505837605 248723.61475452458 280792.07325470715 271793.395752086 263294.6965742329 279739.4158289039 1.2006527723575122 1.156306458391657 1.0223819341131908 1.0605362765090105 1.0360729814386562 0.8891260962189561 1.0037629928649279 0.9715949214619155 0.9412141502979007 1.0 18.093724021116515 -4.82271703904433 0.6337962533299054 0.9630783131402129 1.3629348101611558 0.7867785909288925 0.040989356548941806 1.456589929562486 0.4588970374868101 0.01997255899866628 0.4222572923234752 1.5041216448456322e-05 4.82271703904433 0.39985649702094295 VQAYEEPSVASS(ph)PNGK ddPTM_PC-9_Lapatinib_30min_R1 2 VQAYEEPSVASSPNGK 16 0 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 VQAYEEPSVAS(0.064)S(0.936)PNGK;VQAYEEPSVAS(0.25)S(0.75)PNGK 237.06 4.2658e-37 27703000.0 284576.0 331940.0 349489.0 328908.0 381479.0 364338.0 315474.0 329970.0 372313.0 303604.0 True False 280517.8940551534 331171.41332433355 320755.3634865526 353096.99152492377 359041.1552365705 348756.1130533598 331807.7000938626 345301.61081470875 330379.18931030104 356081.54687309975 0.7877911577235546 0.9300437392290827 0.9007918728258708 0.99161833750054 1.0083116027479107 0.9794276510982732 0.9318306522974978 0.9697262153766346 0.9278189005060729 1.0 18.441848147642773 -3.8878864009213943 1.022586552735776 0.9685083206139297 1.2652872286966332e-17 0.745240995969712 0.031242056466646292 4.9760601070688235 1.0814818924649388 0.010160153801725738 8.147069396034869 0.00012945344105338237 3.8878864009213943 -0.9685083206139297 VQAYEEPSVASSPNGKES(ph)DLRR ddPTM_PC-9_Lapatinib_30min_R1 1 VQAYEEPSVASSPNGKESDLRR 22 2 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 VQAYEEPS(0.004)VAS(0.315)S(0.315)PNGKES(0.366)DLRR 42.123000000000005 0.030538 7457300.0 179630.0 21784.0 36715.0 32817.0 16018.0 18467.0 11489.0 4079.7 32108.0 8234.2 True False 177068.4432598923 21733.56048640498 33696.43442399847 35230.47165430277 15075.852732599658 17677.209458679565 12083.844203891262 4269.257755677079 28491.658927770815 9657.470498618168 18.33486763280592 2.250440266891285 3.4891573760251093 3.6480019958998264 1.5610560482433549 1.8304181681123328 1.251243191021942 0.4420679054922242 2.9502196182579614 1.0 13.237429650019912 -4.761334803817058 8.009111383560244 2.0652520301634105 18.535202826160383 0.959585303717828 1.0028657951442943 0.017766565718897245 10.092616060203008 0.2701057380365644 1.5828744343372414 1.7324678985717476e-05 4.761334803817058 16.469950795996972 VQDGMGLY(ph)TARR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VQDGMGLYTARR 12 1 Q9NQX1-3;Q9NQX1-4;Q9NQX1-2;Q9NQX1 Q9NQX1-3 PRDM5 PR domain zinc finger protein 5 1 VQDGMGLY(0.806)T(0.194)ARR 67.334 0.011392 2345400.0 1134.2 0.0 0.0 1078.7 937.26 1001.3 0.0 0.0 1390.8 0.0 True False 1326.1976585288855 0.0 0.0 1018.2639361925861 753.6106311772064 948.7900653120911 0.0 0.0 1411.1378188649041 0.0 0.0 VQDTS(ph)NTGLGEDIIHQLSK ddPTM_PC-9_AZD4547_30min_R2 6 VQDTSNTGLGEDIIHQLSK 19 0 Q8IWA0 Q8IWA0 WDR75 WD repeat-containing protein 75 1 VQDT(0.121)S(0.68)NT(0.199)GLGEDIIHQLSK;VQDT(0.206)S(0.659)NT(0.135)GLGEDIIHQLSK;VQDT(0.092)S(0.671)NT(0.237)GLGEDIIHQLSK;VQDT(0.062)S(0.699)NT(0.239)GLGEDIIHQLSK;VQDT(0.251)S(0.696)NT(0.053)GLGEDIIHQLSK;VQDT(0.124)S(0.677)NT(0.199)GLGEDIIHQLSK 191.45 8.9076e-12 222842200.0 205497.30000000002 190464.5 279156.1 311747.2 286017.0 273423.0 251055.0 295002.0 212327.80000000002 249375.5 True False 270841.1667906269 252028.42488870063 275454.3077166448 239878.699486227 246308.47656279217 256325.81658647768 273398.40864202054 249416.21937157074 223551.01403220516 240644.93964899427 1.125480416025689 1.0473040707039605 1.1446503222483033 0.9968158891523549 1.0235348265459425 1.06516188106991 1.136107034042771 1.0364490511845805 0.928966195417521 1.0 17.876546560652294 -1.5228812456470417 0.10312850117716651 0.9504272922632333 1.4037395527714949 0.2643893613215148 0.056350986561530494 194.97605735269255 1.4238818733569811 0.6837499556509891 12.519984126834567 0.029999827281284197 1.5228812456470417 0.45331226050826157 VQDTS(ph)NTGLGEDIIHQLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 VQDTSNTGLGEDIIHQLSK 19 0 Q8IWA0 Q8IWA0 WDR75 WD repeat-containing protein 75 1 VQDT(0.002)S(0.713)NT(0.284)GLGEDIIHQLSK;VQDT(0.165)S(0.789)NT(0.046)GLGEDIIHQLSK;VQDT(0.03)S(0.553)NT(0.416)GLGEDIIHQLSK;VQDT(0.094)S(0.516)NT(0.39)GLGEDIIHQLSK;VQDT(0.101)S(0.674)NT(0.225)GLGEDIIHQLSK;VQDT(0.078)S(0.478)NT(0.444)GLGEDIIHQLSK 176.77 5.8543e-09 210418500.0 335751.0 344052.0 383888.0 400243.0 446172.0 373796.0 426311.0 375948.0 391318.0 308606.0 True False 392587.0129154747 378207.2087995452 393041.3458233468 377818.6823153136 358747.7994725006 354193.4797297494 385927.7358556404 366079.76334983273 397040.2854490772 364553.82487624866 1.076897253920576 1.037452312914098 1.0781435250522156 1.0363865540117918 0.9840736127080303 0.9715807531301689 1.0586303297918964 1.004185770027518 1.0891129330047666 1.0 18.47577231271795 -5.987632940163957 9.130336705818214 1.017161192915435 1.0608660324186774 0.26740083330602604 0.03411136435089398 0.2633714447623673 158.8276863683368 0.009736670667038115 0.014173405567910996 1.0288855309104935e-06 5.987632940163957 0.04370483950324244 VQDTS(ph)NTGLGEDIIHQLSK ddPTM_PC-9_Lapatinib_30min_R1 4 VQDTSNTGLGEDIIHQLSK 19 0 Q8IWA0 Q8IWA0 WDR75 WD repeat-containing protein 75 1 VQDT(0.202)S(0.66)NT(0.138)GLGEDIIHQLSK;VQDT(0.185)S(0.534)NT(0.281)GLGEDIIHQLSK;VQDT(0.261)S(0.592)NT(0.147)GLGEDIIHQLSK;VQDT(0.166)S(0.777)NT(0.058)GLGEDIIHQLSK 135.17 1.4540999999999999e-05 182269400.0 394207.9 434476.4 505673.6 418283.5 442658.4 459995.3 384833.7 411208.4 478319.2 310333.9 True False 388586.42305712437 433470.3965899501 464099.0685645434 449045.4639428513 416622.1032118988 440322.3733204174 404758.5059802445 430314.6434540689 424445.8547715267 363974.70112107135 1.067619320409487 1.1909355107781567 1.2750860626716114 1.2337271314730258 1.1446457732602546 1.2097609310872133 1.1120512077722868 1.182265256702362 1.1661410902026963 1.0 18.47347865058716 -10.527910999703042 0.4103598305808095 0.9264950943259752 1.1891753902698943 0.47168179078233086 0.055965269316691435 14.263640732351506 1.6632194486106502 1.289219532334054 0.03658157440388229 2.9654390369262075e-11 10.527910999703042 0.26268029594391906 VQDTSNT(ph)GLGEDIIHQLSK ddPTM_PC-9_Lapatinib_30min_R1 1 VQDTSNTGLGEDIIHQLSK 19 0 Q8IWA0 Q8IWA0 WDR75 WD repeat-containing protein 75 1 VQDT(0.061)S(0.405)NT(0.535)GLGEDIIHQLSK 162.73 3.0106e-06 8724800.0 41593.0 41504.0 48954.0 36138.0 39205.0 41046.0 41863.0 41682.0 42496.0 26354.0 True False 40999.87619277795 41407.90003799816 44929.19108790474 38795.70907283402 36899.03897999562 39290.55826289933 44030.461302767835 43618.697887622155 37709.65297728134 30909.25378550232 1.3264595928876335 1.339660294789133 1.4535838166684676 1.2551486794880427 1.193786146895036 1.2711584218616168 1.424507418015374 1.411185730665587 1.2200117556693872 1.0 14.915751204468641 -8.57993749673089 5.118725431323773 1.0000452606565975 1.3316321336231176 0.6415492367758153 0.07647452791011206 0.23668457096648068 18.808504327918182 0.08120231282051193 0.021108367636860362 2.6306465649275552e-09 8.57993749673089 0.3315868729665201 VQEHEDS(ph)GDS(ph)EVENEAK ddPTM_PC-9_Lapatinib_30min_R1 1 VQEHEDSGDSEVENEAK 17 0 Q9Y5J1 Q9Y5J1 UTP18 U3 small nucleolar RNA-associated protein 18 homolog 2 VQEHEDS(1)GDS(1)EVENEAK 186.45 3.3607e-07 8609900.0 52865.0 50597.0 55509.0 46820.0 51996.0 46347.0 42424.0 50051.0 51850.0 46204.0 True False 52111.135405746296 50479.84575517039 50945.26429093647 50263.29898694144 48937.6975080692 44364.84685013386 44620.50713777375 52376.55218015873 46010.106995294555 54190.29983703992 0.961632165949514 0.9315291833957823 0.9401177783503346 0.9275331403976784 0.9030711705828118 0.8186861298709734 0.8234039536956932 0.9665300309772143 0.8490469167665672 1.0 15.725747009183335 -6.269753576543685 3.1399630438180894 0.8834986124819685 0.9412201785628033 0.14210366236798422 0.05494756123052832 0.4465587168751294 9.073112800347486 0.017397566602463627 0.021523485779616394 5.373366005729985e-07 6.269753576543685 0.057721566080834785 VQEHEDS(ph)GDSEVENEAK ddPTM_PC-9_Lapatinib_30min_R1 1 VQEHEDSGDSEVENEAK 17 0 Q9Y5J1 Q9Y5J1 UTP18 U3 small nucleolar RNA-associated protein 18 homolog 1 VQEHEDS(0.89)GDS(0.11)EVENEAK 115.83 8.3859e-05 17147000.0 65819.0 57237.0 62693.0 62370.0 63442.0 60516.0 63135.0 66197.0 63736.0 65814.0 True False 64880.40899027366 57104.4712431308 57538.62354197842 66956.89786022082 59710.46629177098 57927.8717496861 66403.8213780725 69272.7542840297 56557.380510165734 77189.86220835736 0.840530182773782 0.7397923718141848 0.7454168448528298 0.8674312396035264 0.7735532177864948 0.7504595822871445 0.8602660955506014 0.8974333196377895 0.7327047735556427 1.0 16.236123761989333 -14.522878745232475 0.22853153237475268 2.0545923028610256 0.7793930053507668 0.5024986041729615 0.058713713727054764 131.98860065046136 1.3177752243942185 64.33711604092444 0.1025139099037929 3.0000000003306213e-15 14.522878745232475 -1.2751992975102588 VQEKPDS(ph)PGGSTQIQR ddPTM_PC-9_Lapatinib_30min_R1 1 VQEKPDSPGGSTQIQR 16 1 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 VQEKPDS(0.605)PGGS(0.363)T(0.032)QIQR 212.41 2.0174e-17 12557000.0 13545.0 12564.0 10013.0 9446.6 13020.0 10446.0 11254.0 9547.7 11256.0 9254.5 True False 13351.84581615122 12534.908829929864 9189.769791297753 10141.334476933804 12254.189198304888 9999.248930815334 11836.677053755086 9991.32099759249 9988.230749065297 10854.127994153885 1.2301168572309655 1.1548517611623208 0.8466612699101607 0.9343297298867309 1.1289888238746666 0.9212392682490022 1.0905230765779075 0.9205088610502741 0.9202241538376028 1.0 13.405956206005223 -5.082606448904495 5.888933978974021 0.974794153768104 1.213193177222286 0.5550364970207009 0.08068427004589751 0.14703563397587296 8.110052294848028 0.020695902103699614 0.058006282865167916 8.26786831943911e-06 5.082606448904495 0.23839902345418196 VQEKPDSPGGS(ph)TQIQR ddPTM_PC-9_AZD4547_30min_R2 1 VQEKPDSPGGSTQIQR 16 1 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 VQEKPDS(0.053)PGGS(0.704)T(0.243)QIQR 69.986 0.0096914 94790000.0 92748.0 116610.0 102780.0 159530.0 127540.0 143420.0 108670.0 126140.0 109030.0 106560.0 True False 122239.93472175612 154301.9020671642 101417.07004474087 122752.82321393046 109833.27250065035 134451.92472773948 118341.41947831499 106647.96140883764 114793.10321084343 102829.36683433947 1.1887648293963293 1.5005626001349224 0.986265627873856 1.1937525922112129 1.0681119205722072 1.3075245804473803 1.1508523598026796 1.0371352532068978 1.116345522148141 1.0 16.649892814220387 -1.5228787452886265 0.1280372550462936 0.9638614715677755 2.0441512322506887 0.23852103724073348 0.1296574112538673 123.82627130875802 1.0803496208331844 0.726594272309847 24.077196230959498 0.02999999999942742 1.5228787452886265 1.0802897606829132 VQEKPDSPGGS(ph)TQIQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VQEKPDSPGGSTQIQR 16 1 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 VQEKPDS(0.056)PGGS(0.782)T(0.162)QIQR;VQEKPDS(0.023)PGGS(0.489)T(0.489)QIQR;VQEKPDS(0.02)PGGS(0.49)T(0.49)QIQR 80.632 0.0037283999999999998 137258000.0 309413.0 289241.0 285656.0 370952.0 397987.0 346378.0 375296.0 325063.0 332039.0 321065.0 True False 361790.50971468736 317954.9349528243 292467.12239641295 350168.76208260964 320004.30432358413 328213.32791638037 339745.2459722559 316530.4406827188 336894.4422189266 379271.54295085813 0.9539089247240577 0.8383305862576182 0.7711285695755656 0.9232666372968052 0.843734021893245 0.8653782072938351 0.8957836470643841 0.8345747171538556 0.8882671228054084 1.0 18.532871603559535 -8.557511892478443 18.997682048079003 1.0000000013754733 0.8637118401160787 0.40893238174826985 0.048143141487314994 438.3840919725692 240472.42383664663 0.045313906397878516 0.011699993966929563 2.770053184530061e-09 8.557511892478443 -0.13628816125939458 VQEKPDSPGGS(ph)TQIQR ddPTM_PC-9_Lapatinib_30min_R1 3 VQEKPDSPGGSTQIQR 16 1 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 VQEKPDS(0.132)PGGS(0.434)T(0.434)QIQR;VQEKPDS(0.127)PGGS(0.437)T(0.437)QIQR;VQEKPDS(0.403)PGGS(0.46)T(0.137)QIQR 105.36 0.0045623 190716000.0 229886.0 184641.0 187372.0 158535.0 188425.0 176190.0 185955.0 190853.0 185340.0 137914.0 True False 226607.78348407036 184213.47510880887 171966.99743683642 170194.19275725633 177342.2119578034 168654.7644189502 195582.84001519688 199720.72712313142 164465.05748327638 161752.25114114644 1.4009559798109419 1.1388618940954496 1.0631505665214915 1.0521905664777635 1.0963817239430753 1.0426733676292428 1.2091506525280415 1.2347322878916434 1.0167713668464664 1.0 17.303426265093968 -4.765884731878686 3.867408731533004 1.099239231650889 1.4353905952460284 0.6140677465660751 0.07338082733976357 0.18334473394760037 4.941526181341739 0.019057506874508738 0.17950172019007843 1.714412277275892e-05 4.765884731878686 0.3361513635951394 VQFDGTNS(ph)AFK ddPTM_PC-9_AZD4547_30min_R2 2 VQFDGTNSAFK 11 0 Q8WWK9-6;Q8WWK9-5;Q8WWK9 Q8WWK9-6 CKAP2 Cytoskeleton-associated protein 2 1 VQFDGT(0.294)NS(0.706)AFK;VQFDGT(0.096)NS(0.904)AFK 107.61 0.0022883 9945500.0 38459.0 36933.0 42213.0 64979.0 53536.0 75373.0 47692.0 61759.0 49433.0 53933.0 True False 50688.16200310533 48870.869985820864 41653.22803851577 49999.09546554245 46103.450498626364 70659.91439481157 51936.4956083538 52215.56563063596 52045.92746053035 52044.82208592759 0.9739328519447646 0.9390150264157607 0.8003337578855592 0.9606929846545045 0.8858412547267077 1.3576742423703532 0.9979185926047563 1.003280701861685 1.000021238896752 1.0 15.667467017184748 VQFDGTNS(ph)AFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VQFDGTNSAFK 11 0 Q8WWK9-6;Q8WWK9-5;Q8WWK9 Q8WWK9-6 CKAP2 Cytoskeleton-associated protein 2 1 VQFDGT(0.138)NS(0.862)AFK 97.631 0.0053106 4261600.0 29472.0 33226.0 31361.0 31446.0 29285.0 17475.0 23201.0 18677.0 19253.0 17085.0 True False 34461.02750146654 36524.45769701582 32108.765177254816 29684.182569307544 23546.814474131486 16558.58023702067 21003.2333193061 18186.748539917262 19534.538701902493 20182.37525521442 1.7074812585581576 1.8097204731925287 1.5909309370788274 1.470797277027053 1.1667018463571481 0.8204475453275754 1.0406720246607046 0.9011203245375413 0.9679008766252847 1.0 14.300808354155429 -6.160944972583368 1.4851377895220985 0.9403000978809001 1.7413377429356016 0.9524456883813133 0.07511764420073887 0.07452920317197513 0.3292250067305371 0.026736051612696807 0.04020167520424602 6.90327266428909e-07 6.160944972583368 0.8010376450547015 VQFDGTNS(ph)AFK ddPTM_PC-9_Lapatinib_30min_R1 2 VQFDGTNSAFK 11 0 Q8WWK9-6;Q8WWK9-5;Q8WWK9 Q8WWK9-6 CKAP2 Cytoskeleton-associated protein 2 1 VQFDGT(0.029)NS(0.971)AFK;VQFDGT(0.111)NS(0.889)AFK 127.79 0.00034242 12153200.0 52829.0 57376.0 68351.0 66360.0 48070.0 54534.0 44888.0 36264.0 54648.0 30824.0 True False 52075.64877234794 57243.14939717096 62731.44462249001 71240.33577047066 45242.617109256185 52201.70794496304 47212.08100132917 37948.95782824074 48492.96677104832 36151.88732960174 1.440468330119727 1.583406942914965 1.735219078621229 1.970584139106285 1.2514593414383324 1.4439552621148897 1.3059368262268058 1.0497088985218077 1.3413675012021158 1.0 15.141783345397544 -6.858921658465043 1.2550887673430065 1.1632579890758858 1.6605218336802117 0.565210533122604 0.18541624836272969 0.3461386138963763 1.1386610317772385 0.09851225255394107 0.08114959408157155 1.38381598032557e-07 6.858921658465043 0.4972638446043258 VQGGHS(ph)PDDHR ddPTM_PC-9_Lapatinib_30min_R1 1 VQGGHSPDDHR 11 0 A2AJT9-3;A2AJT9-2;A2AJT9 A2AJT9-3 CXorf23 Uncharacterized protein CXorf23 1 VQGGHS(1)PDDHR 60.246 0.036493 5650800.0 12563.0 18767.0 19157.0 14415.0 16761.0 14720.0 20948.0 21820.0 19287.0 15150.0 True False 12383.849316227956 18723.546164541032 17581.98540815849 15475.127187030344 15775.150933393877 14090.459913995961 22032.5849406488 22833.836857826296 17114.694958886128 17768.657313893913 0.6969490771001929 1.053740067906001 0.9894943156121617 0.8709227103462579 0.8878077085238598 0.7929951973905285 1.2399690393837908 1.2850625938951363 0.9631957359830206 1.0 14.117047047985668 -7.262447140082766 24.99711401527767 1.1458120612007563 0.8944405457337525 0.44701681635132706 0.1292937873259721 83.2641358046262 2065293.7697766619 0.05162925873875297 0.03706823232019449 5.464530570716871e-08 7.262447140082766 -0.25137151546700376 VQGLLENGDSVT(ph)SPEK ddPTM_PC-9_Lapatinib_30min_R1 4 VQGLLENGDSVTSPEK 16 0 P41229-4;P41229-3;P41229-2;P41229-5;P41229 P41229-4 KDM5C Lysine-specific demethylase 5C 1 VQGLLENGDSVT(0.771)S(0.229)PEK;VQGLLENGDSVT(0.5)S(0.5)PEK;VQGLLENGDSVT(0.941)S(0.059)PEK;VQGLLENGDSVT(0.576)S(0.424)PEK 270.99 2.2722999999999993e-169 35915500.0 277405.0 383739.0 262082.0 321170.0 355425.0 335598.0 354289.0 328537.0 304964.0 284764.0 True False 273449.1538301534 382850.4759223545 240534.629625776 344789.9131917126 334519.60029243573 321245.25585714745 372632.3508706097 343802.0284032856 270615.74290671153 333985.0779758211 0.8187466203204138 1.1463101233225486 0.7201957377364911 1.0323512513833737 1.0016004377197154 0.9618551158156954 1.1157155676805013 1.0293933803478945 0.8102629750611278 1.0 18.349424120815193 VQGLLENGDSVTS(ph)PEK ddPTM_PC-9_AZD4547_30min_R2 4 VQGLLENGDSVTSPEK 16 0 P41229-4;P41229-3;P41229-2;P41229-5;P41229 P41229-4 KDM5C Lysine-specific demethylase 5C 1 VQGLLENGDSVT(0.012)S(0.988)PEK;VQGLLENGDSVT(0.027)S(0.973)PEK;VQGLLENGDSVT(0.022)S(0.978)PEK;VQGLLENGDS(0.001)VT(0.04)S(0.959)PEK 199.33 4.0389e-12 60437700.0 216505.0 255179.0 216951.0 186456.0 216078.0 249674.0 280386.0 279140.0 283942.0 228061.0 True False 285349.086416244 337660.6214526788 214074.0879867347 143471.44991648334 186079.29947777538 234061.8453107903 305339.81082034466 236005.32699907216 298950.5944409183 220076.65380636617 1.2965895358773838 1.5342864207203395 0.9727251132011812 0.6519158094920704 0.8455203960048244 1.0635469108719227 1.3874248155781077 1.0723778416165888 1.3583930383817502 1.0 17.74764658366349 -5.266415349255223 24.764036723395407 1.0384463332920502 1.4154379890665414 0.330546222265513 0.2113307533510969 410.9367074751516 2045130.3693509882 0.06123824630927276 0.13413769611655088 5.4148278100763305e-06 5.266415349255223 0.37699165577449123 VQGLLENGDSVTS(ph)PEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VQGLLENGDSVTSPEK 16 0 P41229-4;P41229-3;P41229-2;P41229-5;P41229 P41229-4 KDM5C Lysine-specific demethylase 5C 1 VQGLLENGDSVT(0.089)S(0.911)PEK;VQGLLENGDSVT(0.01)S(0.99)PEK;VQGLLENGDS(0.003)VT(0.202)S(0.795)PEK;VQGLLENGDSVT(0.006)S(0.994)PEK 253.36 3.3177e-57 47098100.0 335088.0 453987.0 311565.0 336310.0 338848.0 266661.0 347969.0 253107.0 249229.0 242045.7 True False 391811.78011032264 499055.8290644398 318993.891216843 317467.6410317318 272453.1668407203 252676.82773013826 315006.8572426031 246463.20943903376 252873.50263005533 285926.66937729256 1.3703226109115065 1.7453979726735953 1.1156493093546191 1.1103114016021345 0.952877769094028 0.8837119960877812 1.1017050558055428 0.8619804860308953 0.8843998469285068 1.0 18.125285665878096 -5.4375504290382315 3.555169296989571 0.9709289690153631 1.5558240704007635 0.788486662616756 0.11917326880187451 0.09705526182168948 2.292573280144255 0.031767969828839615 0.0710385427625614 3.6513172673707283e-06 5.4375504290382315 0.5848951013854005 VQGLLENGDSVTS(ph)PEK ddPTM_PC-9_Lapatinib_30min_R1 1 VQGLLENGDSVTSPEK 16 0 P41229-4;P41229-3;P41229-2;P41229-5;P41229 P41229-4 KDM5C Lysine-specific demethylase 5C 1 VQGLLENGDSVT(0.187)S(0.813)PEK 211.9 1.3186999999999998e-63 0.0 67780.0 113710.0 79161.0 91686.0 95705.0 86018.0 97108.0 99924.0 88645.0 82476.0 True False 66813.44477067036 113446.71148132176 72652.6881502967 98428.89429553004 90075.82006326957 82339.21065775168 102135.77708690686 104566.83383049637 78660.86662676733 96731.86670763794 0.6907076958682818 1.1727956395610841 0.751072946518048 1.0175436249258085 0.9311907557363119 0.8512108104624243 1.0558648412689242 1.0809967530817823 0.8131846236826139 1.0 16.56170361948498 -7.262116616616607 24.996282814554423 0.9942612810352515 0.9143712461841845 0.07464760555728245 0.14231349095519327 180.9968015310403 6680212.46450936 0.05347324787930268 0.038518412108480025 5.4686909805995365e-08 7.262116616616607 -0.07989003485106694 VQGPGILPGLDSES(ph)ASSSIR ddPTM_PC-9_AZD4547_30min_R2 1 VQGPGILPGLDSESASSSIR 20 0 Q9H813;Q9H813-2 Q9H813 TMEM206 Transmembrane protein 206 1 VQGPGILPGLDS(0.071)ES(0.357)AS(0.357)S(0.107)S(0.107)IR 75.564 0.0023087 2553000.0 6331.1 9646.3 8235.9 8238.6 6713.8 6246.9 8936.3 10921.0 6447.0 7223.1 True False 8344.258104939294 12764.277831322224 8126.686584758535 6339.318055101157 5781.704758623682 5856.280355471448 9731.613388093025 9233.410389614064 6787.775258188644 6970.221467540533 1.1971295523101355 1.8312585748908985 1.1659151179920924 0.90948588715905 0.82948652141806 0.8401856932012028 1.396169896955492 1.3246939760254282 0.9738249049615542 1.0 12.766988780791142 -5.4677790104299335 8.641464491650009 1.0494457900447065 1.5122218492035127 0.40417222257009067 0.22737660101976692 0.3877285555181958 57.320577538887356 0.06252068459309684 0.12974089966254632 3.4058144956340353e-06 5.4677790104299335 0.46277605915880615 VQGVDPGCMS(ph)PDVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VQGVDPGCMSPDVK 14 0 E9PC47;P53667-4;P53667-2;P53667;P53667-3 E9PC47 LIMK1 LIM domain kinase 1 1 VQGVDPGCMS(1)PDVK 81.311 0.046294999999999996 0.0 18140.0 17900.0 15153.0 17022.0 18613.0 17429.0 17402.0 21229.0 17167.0 14456.0 True False 21210.743718668647 19676.993703021224 15514.304988072508 16068.312526068592 14965.91626453848 16514.992557999034 15753.55658043037 20671.761243984787 17418.034898226786 17076.75836636696 1.2420825582707582 1.1522675018799517 0.9085040998547044 0.940946295622211 0.8763909369364956 0.9671034867206216 0.9225144633689574 1.2105202170394507 1.019984854533749 1.0 14.059746517703397 -5.084885118298994 4.295343199444515 0.9811182172200392 1.225766847074818 0.5047082595157999 0.08760636064322172 0.1819909585510272 5.91169899603599 0.024653192756291346 0.07728804696939205 8.22460182365508e-06 5.084885118298994 0.24464862985477875 VQGVDPGCMS(ph)PDVK ddPTM_PC-9_Lapatinib_30min_R1 1 VQGVDPGCMSPDVK 14 0 E9PC47;P53667-4;P53667-2;P53667;P53667-3 E9PC47 LIMK1 LIM domain kinase 1 1 VQGVDPGCMS(1)PDVK 113.01 0.0022178000000000002 0.0 27489.0 34774.0 35519.0 32986.0 37745.0 33049.0 33368.0 35477.0 43387.0 26039.0 True False 27097.001819134788 34693.48293950821 32598.764927304983 35411.90047807025 35524.91330952516 31635.571310981828 35095.631769122054 37125.39093515595 38500.29917463538 30539.806455213457 0.8872682889746688 1.1360086053716847 1.0674188448152409 1.1595325769337048 1.1632330860256874 1.035879888674976 1.1491766269242636 1.2156393652854427 1.2606595667558 1.0 14.898403298691793 -4.190873345407554 1.6465347463251738 1.1404326179671644 1.310699753782301e-14 0.4720344372972445 0.07631485607556691 5.567798334144513 3.6637248070834825 0.021116532721566342 16.434481765055597 6.443571539113602e-05 4.190873345407554 -1.1404326179671513 VQIPVSRPDPEPVS(ph)DNEEDSYDEEIHDPR ddPTM_PC-9_AZD4547_30min_R2 2 VQIPVSRPDPEPVSDNEEDSYDEEIHDPR 29 1 A0A087X0K9;G5E9E7;Q07157-2;H0YKB1;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 VQIPVS(0.001)RPDPEPVS(0.392)DNEEDS(0.283)Y(0.325)DEEIHDPR;VQIPVS(0.003)RPDPEPVS(0.603)DNEEDS(0.185)Y(0.209)DEEIHDPR 52.577 0.0029949 13982000.0 18015.8 19433.6 30841.0 33005.0 35277.0 27277.0 25771.0 28647.0 24770.0 29247.0 True False 23744.449648080958 25715.131155239156 30432.028188848566 25396.20717216683 30379.39747534447 25571.36487797061 28064.56907495778 24220.26439257159 26079.291631042757 28223.071432093966 0.8413134518406764 0.911138648290317 1.0782677662163545 0.8998385322189789 1.0764029545274236 0.9060447208765535 0.9943839437349139 0.858172522110029 0.9240415839853134 1.0 14.784587380196456 -10.451978789250035 17.977462334336565 0.9999999999194243 0.9468547437767506 0.04359761420667052 0.07809398749083205 0.0 0.0 0.07428674461189115 0.018017182036359464 3.532004195226281e-11 10.451978789250035 -0.053145256142673736 VQIPVSRPDPEPVSDNEEDS(ph)YDEEIHDPR ddPTM_PC-9_Lapatinib_30min_R1 1 VQIPVSRPDPEPVSDNEEDSYDEEIHDPR 29 1 A0A087X0K9;G5E9E7;Q07157-2;H0YKB1;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 VQIPVSRPDPEPVS(0.01)DNEEDS(0.522)Y(0.468)DEEIHDPR 47.806000000000004 0.008537200000000002 6820900.0 13551.0 10905.0 12221.0 12939.0 18806.0 11496.0 11567.0 12128.0 11779.0 9942.6 True False 13357.760255050947 10879.750142501196 11216.23655442422 13890.577223238684 17699.868054018552 11004.342878484882 12165.882662234335 12691.511155440758 10452.32498163113 11661.165162318264 1.1454910439151516 0.9329899706470051 0.9618452700308388 1.191182615964013 1.5178472997890189 0.9436743863335519 1.0432819099027093 1.088357036263575 0.8963362439464142 1.0 13.50942432674272 VQIPVSRPDPEPVSDNEEDSY(ph)DEEIHDPR ddPTM_PC-9_Lapatinib_30min_R1 1 VQIPVSRPDPEPVSDNEEDSYDEEIHDPR 29 1 A0A087X0K9;G5E9E7;Q07157-2;H0YKB1;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 VQIPVSRPDPEPVS(0.004)DNEEDS(0.469)Y(0.527)DEEIHDPR 66.793 0.00022309999999999997 6266000.0 15584.0 14860.0 15861.0 10307.0 15699.0 15690.0 10634.0 11360.0 15826.0 13021.0 True False 15361.769302244405 14825.592582995681 14556.969805230561 11065.01116314407 14775.615685421544 15018.975275176395 11184.576487438395 11887.827071718913 14043.509224831841 15271.662500608101 1.0059002614569774 0.970791004738701 0.9532013822758929 0.7245452918242185 0.9675184797223744 0.9834538495450875 0.7323745196040731 0.7784238992477441 0.9195795954941149 1.0 13.898569504606712 -5.542723938465539 24.989361875263295 0.8637386125956428 0.9817583468065191 0.20173342603627364 0.09560355656099766 340.9111609468002 429278.5829877925 0.026416492459247636 0.045761569698617895 2.8659991782213292e-06 5.542723938465539 0.1180197342108763 VQIS(ph)PDSGGLPER ddPTM_PC-9_AZD4547_30min_R2 1 VQISPDSGGLPER 13 0 A0A087WTP3;Q92945;M0QXW7;M0QYH3 A0A087WTP3 KHSRP Far upstream element-binding protein 2 1 VQIS(0.92)PDS(0.08)GGLPER 93.10600000000001 0.0042861999999999996 1428600.0 5542.2 6258.7 7777.6 12254.0 11092.0 9004.6 6229.2 8488.7 6865.2 7654.1 True False 7304.5043150786705 8281.702379450813 7674.463942206439 9429.02962241274 9552.067261856757 8441.540938526025 6783.586732440608 7176.966465920425 7228.080456416418 7386.13228872672 0.9889484820394246 1.1212502099496622 1.0390368926805973 1.2765855327021487 1.293243457937499 1.1428905695894658 0.9184220465146877 0.9716812785596138 0.9786015432526801 1.0 12.8506033867102 -7.249534401992148 21.917523685626435 0.9648163354088373 1.1507264996122375 0.4839808695389245 0.08908199355309256 131.57624845076586 242237.33052143425 0.03753638120191942 0.02875521032249104 5.629445228140183e-08 7.249534401992148 0.18591016420340023 VQIS(ph)PDSGGLPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VQISPDSGGLPER 13 0 A0A087WTP3;Q92945;M0QXW7;M0QYH3 A0A087WTP3 KHSRP Far upstream element-binding protein 2 1 VQIS(0.998)PDS(0.002)GGLPER;VQIS(0.976)PDS(0.024)GGLPER;VQIS(0.876)PDS(0.124)GGLPER 121.92 0.00018977 55015000.0 76755.0 83224.0 92886.0 87679.0 96534.0 96165.0 88136.0 90665.0 91696.0 69577.0 True False 89748.10551964802 91485.92871174519 95100.75451211681 82766.62988915334 77618.85567511729 91121.93811119277 79787.12003061762 88285.13981750817 93036.88052821103 82190.75932877102 1.0919488547446907 1.113092633026939 1.157073560200418 1.0070065122294196 0.9443744808906598 1.1086640256807478 0.9707553584151887 1.0741492174851317 1.131962781315287 1.0 16.326688580999544 -5.765666173985436 24.99967576849788 1.0336950055364116 1.1199437807128916 0.32495156577665607 0.057367171661218685 127.62779228594675 754869.6600987201 0.016309436295918446 0.025195809596674886 1.7152752692088782e-06 5.765666173985436 0.08624877517648 VQISPDS(ph)GGLPER ddPTM_PC-9_AZD4547_30min_R2 2 VQISPDSGGLPER 13 0 A0A087WTP3;Q92945;M0QXW7;M0QYH3 A0A087WTP3 KHSRP Far upstream element-binding protein 2 1 VQIS(0.055)PDS(0.945)GGLPER;VQIS(0.11)PDS(0.89)GGLPER 149.59 7.5523e-05 110635000.0 84588.0 82625.0 122292.0 165830.0 144458.0 121411.0 92155.0 146392.0 88956.0 116125.0 True False 111485.22446030013 109331.91543006107 120670.3281758266 127600.45554796001 124402.50022658677 113819.1509769875 100356.6164721094 123770.48015350064 93658.03255272677 112059.49909569885 0.9948752703694643 0.9756595051053332 1.0768415810316454 1.138684864537804 1.1101468526139582 1.0157028355069293 0.8955654565830676 1.1045068124729043 0.8357884276525526 1.0 16.773905423306502 -7.001956579312712 24.333850165741502 0.9659540816615543 1.060283004502747 0.26131567878567863 0.0791204079831294 80.85598019243221 1005621.5836988239 0.028321210538634827 0.024577487624693854 9.955049427884086e-08 7.001956579312712 0.09432892284119265 VQISPDS(ph)GGLPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VQISPDSGGLPER 13 0 A0A087WTP3;Q92945;M0QXW7;M0QYH3 A0A087WTP3 KHSRP Far upstream element-binding protein 2 1 VQIS(0.055)PDS(0.945)GGLPER;VQIS(0.344)PDS(0.656)GGLPER 141.06 7.5523e-05 45904900.0 143191.0 132630.0 149371.0 170324.0 190471.0 158483.0 179054.0 166524.0 156384.0 145546.0 True False 167430.40814883565 145796.62987886605 152932.5711326718 160781.2984778586 153149.5748575142 150171.8724866234 162092.7088812997 162152.92144676225 158670.82015053878 171932.33765849815 0.9738156906898777 0.8479884113973699 0.889492769163851 0.9351428629860871 0.890754915237113 0.8734358790892693 0.9427703426173238 0.9431205534402706 0.9228678113229627 1.0 17.391481392096914 -8.765699794253846 0.5625407826686137 1.0012647200054983 0.900097579443241 0.3814687114740175 0.03489733708915027 1.2530936865984472 0.8436445306656478 0.04076871542366996 0.016175552223222464 1.7151424888368811e-09 8.765699794253846 -0.10116714056225729 VQISPDS(ph)GGLPER ddPTM_PC-9_Lapatinib_30min_R1 2 VQISPDSGGLPER 13 0 A0A087WTP3;Q92945;M0QXW7;M0QYH3 A0A087WTP3 KHSRP Far upstream element-binding protein 2 1 VQIS(0.322)PDS(0.678)GGLPER;VQIS(0.052)PDS(0.948)GGLPER 144.88 9.4462e-05 95140000.0 131088.0 118064.0 129270.0 100527.0 129826.0 114390.0 104553.0 96794.0 126349.0 109781.0 True False 129218.6610814051 117790.63006183063 118641.91959663053 107920.09092824119 122189.8899277366 109497.80635611388 109966.24275824205 101291.40260386982 112118.24510604574 128756.49957601215 1.003589422723628 0.9148324973862173 0.9214441211691188 0.8381719857530759 0.9489997812157132 0.8504254675817061 0.8540636249071282 0.7866896268337261 0.8707773625039882 1.0 16.974285735232904 -1.5228787823690282 0.6450724338987393 0.8670258667204493 12.417119323696722 0.2730629159206468 0.057753081143295706 250.8655944654481 1.649631531862106 0.023566484125537378 4133.098667568778 0.029999997438004126 1.5228787823690282 11.550093456976272 VQKS(ph)PPEPEIINQVQQNELKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VQKSPPEPEIINQVQQNELKK 21 2 A0A3B3ITL0;Q9Y2H2;A0A3B3IRJ9;Q9Y2H2-4 A0A3B3ITL0 INPP5F Phosphatidylinositide phosphatase SAC2 1 VQKS(1)PPEPEIINQVQQNELKK 46.159 0.022101 5478800.0 22789.0 18433.0 19125.0 30563.0 17660.0 19486.0 21083.0 14608.0 17375.0 16401.0 True False 26646.727596733173 20262.906420546933 19581.012531966393 28850.654196582902 14199.649773370747 18464.119856857506 19085.86561229821 14224.555478455393 17629.076504729426 19374.37146975543 1.3753595897720001 1.0458613561827572 1.01066569114428 1.4891143303214003 0.7329089253572567 0.9530177474753757 0.9851088920274087 0.7341944228054462 0.9099173375636719 1.0 14.241861887759537 -6.277691206666487 24.973728498175348 0.8808881535503797 1.201395020731935 0.5312197931215749 0.15752029455307365 677.125314166799 1040517.094717995 0.04822293056271619 0.054842699148750736 5.276048672449323e-07 6.277691206666487 0.3205068671815553 VQMT(ph)SPSSTGSPMFK ddPTM_PC-9_AZD4547_30min_R2 3 VQMTSPSSTGSPMFK 15 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 VQMT(0.292)S(0.19)PS(0.292)S(0.097)T(0.097)GS(0.033)PMFK;VQMT(0.363)S(0.206)PS(0.271)S(0.076)T(0.076)GS(0.006)PMFK;VQMT(0.626)S(0.368)PS(0.003)S(0.001)T(0.001)GS(0.002)PMFK 77.24 0.011655 33359400.0 127720.0 131059.0 160013.0 214965.0 155283.0 165250.0 117309.0 160340.0 117869.0 127018.0 True False 168332.3032589672 173421.25875156894 157891.12306936324 165408.1404261429 133724.63582968852 154916.89137678806 127749.27374235442 135563.13724665478 124099.31470566726 122571.13848127045 1.3733437197753475 1.4148621029417026 1.2881590644072372 1.3494868569848373 1.090996114473738 1.2638937134491919 1.0422459587570463 1.105995578782762 1.012467667701645 1.0 16.90325978566942 -6.4120102396426075 0.46576424730337973 0.996129003897936 1.4557838292948808 0.8182214171656734 0.06477862010016548 0.5170754036168089 0.2206458925210924 0.05440541805631691 0.10886291788518718 3.8724851440465357e-07 6.4120102396426075 0.4596548253969448 VQMT(ph)SPSSTGSPMFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VQMTSPSSTGSPMFK 15 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 VQMT(0.486)S(0.074)PS(0.071)S(0.105)T(0.105)GS(0.159)PMFK 68.044 0.025391 12034000.0 46023.0 40455.0 42645.0 46974.0 75002.0 69265.0 98797.0 80872.0 88762.0 71330.0 True False 53813.784904315704 44471.10504221916 43661.81853206314 44342.19907176276 60305.89650636196 65632.62146593629 89438.23293166187 78749.19569096691 90059.97632879412 84261.56435203063 0.6386516238826373 0.527774500559073 0.5181700442879438 0.5262446693549211 0.7156987526888782 0.7789152975101938 1.0614357046351999 0.9345802715217347 1.0688144353994984 1.0 16.362587079949577 -6.858470053045701 1.4922320654875343 1.0179752606946868 0.5489940768662873 0.9240240176769221 0.05882816479084209 0.09429697072441869 0.43459772593107343 0.02673168260299514 0.02232800786800577 1.385255703506949e-07 6.858470053045701 -0.4689811838283995 VQMT(ph)SPSSTGSPMFK ddPTM_PC-9_Lapatinib_30min_R1 4 VQMTSPSSTGSPMFK 15 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 VQMT(0.88)S(0.099)PS(0.012)S(0.004)T(0.004)GS(0.001)PMFK;VQMT(0.471)S(0.471)PS(0.025)S(0.025)T(0.006)GS(0.002)PMFK;VQMT(0.899)S(0.089)PS(0.009)S(0.002)T(0.001)GSPMFK;VQMT(0.494)S(0.333)PS(0.043)S(0.1)T(0.03)GSPMFK 184.51 1.1727e-06 47646300.0 206339.0 158848.3 222496.0 204052.8 316462.0 393898.0 401225.0 402064.0 468818.0 367521.0 True False 203396.56802206155 158480.4965209606 204203.23773939742 219059.5236121866 297848.32734823035 377051.9007610853 421998.46729099797 420745.36124679603 416014.77996759873 431046.5151590494 0.4718668655678875 0.3676644885122984 0.4737382870710592 0.5082039081822922 0.690988830377921 0.8747359913626932 0.9790091149102252 0.9761019900405588 0.965127347831813 1.0 18.717484036485097 -6.543534188619017 1.2843913972813839 0.9868682972418922 0.422687968322108 0.9867405761102437 0.027874872853517235 0.042277125232253056 0.14528900216643115 0.011896175254965483 0.01310327680917008 2.8606571545254465e-07 6.543534188619017 -0.5641803289197842 down VQMTS(ph)PSSTGSPMFK ddPTM_PC-9_AZD4547_30min_R2 2 VQMTSPSSTGSPMFK 15 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 VQMT(0.14)S(0.639)PS(0.093)S(0.093)T(0.022)GS(0.015)PMFK;VQMT(0.141)S(0.8)PS(0.014)S(0.02)T(0.02)GS(0.005)PMFK 78.508 0.011728 46736000.0 201527.0 183180.0 235280.0 312980.0 271890.0 266850.0 168299.0 260600.0 177577.0 210970.0 True False 265608.3939779976 242389.35271986178 232160.03347077896 240827.29649279724 234142.7666630215 250163.82731555752 183277.284961636 220330.25799225594 186963.35768936918 203584.0045142702 1.3046623904059211 1.1906109878238078 1.1403648043208903 1.1829382031627955 1.15010394466727 1.2287990302205805 0.9002538553994757 1.0822572162186344 0.9183597608046068 1.0 17.635264688529823 -7.2536633852921115 24.97505854960444 0.9820724744553435 1.193475279551595 0.752767371654567 0.06288351039288473 296.2060359032407 951361.1213222303 0.023566910143537036 0.01790399764674958 5.5761778210504544e-08 7.2536633852921115 0.21140280509625153 VQMTS(ph)PSSTGSPMFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VQMTSPSSTGSPMFK 15 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 VQMT(0.172)S(0.283)PS(0.094)S(0.172)T(0.172)GS(0.105)PMFK 86.777 0.0032101 12379000.0 23744.0 30656.0 27836.0 30997.0 42604.0 51532.0 59439.0 53125.0 47631.0 43739.0 True False 27763.390234623388 33699.325081554096 28499.71580861788 29260.338583629884 34256.05203537297 48829.57120309866 53808.50761890586 51730.52504059029 48327.51326600099 51668.53446226653 0.5373365148357161 0.6522214231983815 0.551587462373859 0.5663086613187892 0.6629963940701691 0.9450543103512804 1.0414173380164702 1.0011997742720773 0.9353374112303208 1.0 15.656998342971491 -6.731780286178524 3.067327223966283 0.995994246902585 0.5825654079093997 0.9648597264594759 0.037627446950676616 0.04231609645939619 0.8183782622842898 0.013672749891144934 0.012944779185773157 1.8544695804130025e-07 6.731780286178524 -0.4134288389931853 VQMTSPS(ph)STGSPMFK ddPTM_PC-9_AZD4547_30min_R2 1 VQMTSPSSTGSPMFK 15 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 VQMT(0.009)S(0.028)PS(0.388)S(0.388)T(0.098)GS(0.09)PMFK 72.531 0.017127 21273000.0 87106.0 91202.0 103190.0 149400.0 108790.0 111230.0 87099.0 111920.0 89509.0 92029.0 True False 114803.8960826462 120681.2629476846 101821.63317685177 114958.13820699065 93686.3863520914 104274.77051643064 94850.64226687948 94625.3356657455 94240.26300375472 88807.09272144739 1.2927334131153292 1.358914690814323 1.146548435001986 1.2944702352498885 1.054942611914438 1.1741716491440521 1.0680525548155069 1.0655155209567284 1.0611794634393565 1.0 16.438387283888623 -5.270180597103776 0.31247629584470676 1.0019531445447314 1.5211455964693337 0.7258548469438991 0.061671704774490764 2.676624125129249 0.26946620665709947 0.06522073581097042 0.516900182266961 5.3680852338734295e-06 5.270180597103776 0.5191924519246023 VQMTSPS(ph)STGSPMFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VQMTSPSSTGSPMFK 15 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 VQMT(0.292)S(0.154)PS(0.312)S(0.096)T(0.096)GS(0.05)PMFK;VQMT(0.079)S(0.354)PS(0.415)S(0.117)T(0.033)GS(0.001)PMFK 107.11 0.00076913 31735500.0 64085.0 86283.0 85778.0 78802.0 123842.0 145912.0 145136.0 137134.0 138967.0 129596.0 True False 74933.32476355456 94848.6060155183 87823.27283487657 74386.97941953118 99576.04910723552 138260.11785660428 131387.6673863548 133534.3778054836 140999.12947526536 153090.72891862868 0.48947003710057047 0.6195581318704972 0.5736681342836685 0.4859012687768285 0.6504381409024614 0.9031253481724082 0.8582339917931309 0.8722564635279791 0.9210167752889185 1.0 17.22402739118626 -6.6620566682655955 3.380301998248442 0.9019793535060474 0.550718998750783 0.9197912017911128 0.051906119342375226 0.0642842544572812 1.4463616514938766 0.017904711815029607 0.017623943310725813 2.1774256356902019e-07 6.6620566682655955 -0.3512603547552644 VQMTSPS(ph)STGSPMFK ddPTM_PC-9_Lapatinib_30min_R1 3 VQMTSPSSTGSPMFK 15 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 VQMT(0.268)S(0.205)PS(0.343)S(0.081)T(0.081)GS(0.022)PMFK;VQMT(0.169)S(0.017)PS(0.34)S(0.2)T(0.2)GS(0.073)PMFK;VQMT(0.025)S(0.089)PS(0.677)S(0.16)T(0.039)GS(0.009)PMFK 84.759 0.005287699999999999 10436000.0 120448.0 88719.0 112206.0 90386.0 130982.0 158124.0 146783.0 155122.0 174086.0 143523.0 True False 118730.38943254213 88513.57660637918 102980.85580768564 97033.28795885698 123277.89628051994 151361.40512504725 154382.7055252651 162329.5344207026 154478.60147315037 168330.75931762336 0.7053398316139579 0.5258312679464773 0.6117768150345656 0.5764441885262623 0.732355136876124 0.8991904137938531 0.9171390074582882 0.9643486138763442 0.9177086950678137 1.0 17.36093930089835 -6.644044462984746 2.0473469785554266 0.9461802393645491 0.5980366759960212 0.9165818648990892 0.048007924760718294 0.07975169450428458 0.6841582278822875 0.017447863606191872 0.01736795470946854 2.269632475456475e-07 6.644044462984746 -0.3481435633685279 VQMTSPSST(ph)GSPMFK ddPTM_PC-9_AZD4547_30min_R2 1 VQMTSPSSTGSPMFK 15 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 VQMT(0.002)S(0.089)PS(0.223)S(0.128)T(0.556)GS(0.003)PMFK 97.45 0.0027566999999999995 0.0 22512.0 22747.0 26028.0 32259.0 31471.0 30658.0 26584.0 30140.0 23023.0 34101.0 True False 29670.347721311224 30099.522908170668 25682.8517136069 24822.185946581718 27101.79487900235 28740.950413492086 28949.924499968096 25482.555548298526 24239.94877761395 32907.134369536594 0.9016387567547727 0.9146807670993972 0.7804645468425384 0.7543101647149372 0.8235841679393248 0.8733957229681687 0.8797461418204849 0.774377837405639 0.7366168231304214 1.0 15.006112778212787 -5.246922498204838 24.055778184530574 0.820460723456422 0.9081597903984171 0.15543598321785523 0.0733314770402057 817.1452867213466 1354072.8381586138 0.018356984097020745 0.04804537809403357 5.663403459918914e-06 5.246922498204838 0.08769906694199514 VQMTSPSSTGS(ph)PMFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VQMTSPSSTGSPMFK 15 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 VQMTS(0.001)PS(0.054)S(0.209)T(0.209)GS(0.527)PMFK;VQMTS(0.002)PS(0.141)S(0.077)T(0.077)GS(0.703)PMFK;VQMT(0.002)S(0.001)PS(0.04)S(0.04)T(0.04)GS(0.877)PMFK;VQMT(0.028)S(0.028)PS(0.122)S(0.122)T(0.122)GS(0.578)PMFK 88.10799999999999 0.008987100000000001 60979000.0 172998.0 180570.0 183095.0 212946.0 261325.0 290206.0 339182.0 323709.0 314819.0 239087.0 True False 202283.14453375115 198495.79625444327 187460.67919165405 201015.3260002467 210120.24218720853 274987.0864815349 307052.2254949737 315211.98174803704 319422.6322959659 282431.58048835 0.7162199927642126 0.7028102024257553 0.6637383782207267 0.7117310523584963 0.7439686518904558 0.9736414249640818 1.087173838577302 1.1160649287271867 1.1309734971693144 1.0 18.107541889060784 -6.849196693366559 2.1835186254829995 1.0942829932580633 0.6956850703792522 0.9620828864791344 0.035714462334511095 0.05142340227649574 0.5019417564185901 0.014225528288694602 0.012371091513746997 1.4151527075869875e-07 6.849196693366559 -0.39859792287881113 VQMTSPSSTGS(ph)PMFK ddPTM_PC-9_Lapatinib_30min_R1 1 VQMTSPSSTGSPMFK 15 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 VQMT(0.011)S(0.033)PS(0.122)S(0.122)T(0.192)GS(0.519)PMFK 67.726 0.025752999999999998 12699000.0 46471.0 38000.0 53179.0 40203.0 69236.0 94460.0 94851.0 91013.0 106720.0 77135.0 True False 45808.31501826232 37912.01333471303 48806.82789687636 43159.662733276506 65163.6746032133 90420.16599701482 99761.92067049263 95241.79623929171 94700.06978857917 90467.68197407328 0.5063500469857326 0.4190669254195997 0.5394946220780111 0.4770727158196165 0.720297825491851 0.9994747740185045 1.1027354574983246 1.0527714887907333 1.046783422788691 1.0 16.465114885748115 -6.594451318898886 2.1253176080623937 1.0582356105684723 0.4807926348301269 0.9787809913251551 0.038656090922290436 0.03927438452162529 0.3607206161258711 0.014204960917758618 0.014609032710973859 2.5441849608885976e-07 6.594451318898886 -0.5774429757383454 VQNS(ph)PPVGR ddPTM_PC-9_AZD4547_30min_R2 1 VQNSPPVGR 9 0 D6RAA5;Q4VXL8;E7EMZ9;E9PBC6;O95359-6;O95359-1;O95359-5;O95359-3;O95359;E9PGB3;H0Y8P9;H0YA73 D6RAA5 TACC2 Transforming acidic coiled-coil-containing protein 2 1 VQNS(1)PPVGR 79.036 0.04292 0.0 68490.0 71384.0 95520.0 120810.0 109620.0 104950.0 86888.0 99818.0 73225.0 94975.0 True False 90268.39531950087 94457.4820097972 94253.34238834062 92959.12099589371 94401.15517893425 98387.45990919131 94620.86367564056 84393.42168945144 77095.52400819969 91649.9541581402 0.9849257007127851 1.0306331615486972 1.0284057777673115 1.0142844243598264 1.0300185749798292 1.0735134655869623 1.0324158320076637 0.9208233922717762 0.8411954453918533 1.0 16.483846538701513 -7.783018310237616 6.068601680533526 0.9091434777955824 1.0293865862183362 0.5811104071384834 0.041355484879048963 0.10458076711444687 12.544985264205403 0.02132683155405085 0.010572845638225989 1.6480929050132113e-08 7.783018310237616 0.12024310842275387 VQNS(ph)PPVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VQNSPPVGR 9 0 D6RAA5;Q4VXL8;E7EMZ9;E9PBC6;O95359-6;O95359-1;O95359-5;O95359-3;O95359;E9PGB3;H0Y8P9;H0YA73 D6RAA5 TACC2 Transforming acidic coiled-coil-containing protein 2 1 VQNS(1)PPVGR;VQNS(1)PPVGR 108.9 0.0024154 0.0 116658.0 141329.0 151211.0 139897.0 161946.0 128670.0 176753.0 136193.0 125457.0 105470.0 True False 136405.89529947328 155359.20910917807 154816.44371091094 132059.02464219366 130213.84383908851 121922.31868941047 160009.67625909692 132618.0780584116 127291.57128367432 124590.87609993968 1.0948305330966313 1.2469549454372388 1.242598563852509 1.0599413759340086 1.0451314567740773 0.9785814379506519 1.2842808499937532 1.0644284895471234 1.0216765084914268 1.0 16.92683889683301 -1.522878760741888 0.10177586835069026 0.9430294868729014 1.670892384221612 0.20582079150895372 0.0945335916537092 211.03821641761684 1.5240423356889907 1.2126015970807322 21.460571731274527 0.029999998931953945 1.522878760741888 0.7278628973487105 VQNS(ph)PPVGR ddPTM_PC-9_Lapatinib_30min_R1 1 VQNSPPVGR 9 0 D6RAA5;Q4VXL8;E7EMZ9;E9PBC6;O95359-6;O95359-1;O95359-5;O95359-3;O95359;E9PGB3;H0Y8P9;H0YA73 D6RAA5 TACC2 Transforming acidic coiled-coil-containing protein 2 1 VQNS(1)PPVGR 92.943 0.013179 0.0 60926.0 75693.0 68953.0 62252.0 66285.0 75631.0 65462.0 67032.0 76601.0 56212.0 True False 60057.18406753994 75517.73750906413 63283.95050627713 66830.21974658432 62386.246621324 72396.43843447207 68851.3020519741 70146.55143234703 67973.38873570986 65928.16930221807 0.910948759887974 1.145454792819849 0.9598924280178369 1.0136823220470632 0.9462760346846927 1.0981108561137674 1.0443381452980476 1.0639845179196723 1.0310219357694645 1.0 16.008607400613734 -6.7683591942655275 24.999722048864903 1.0512930514413066 1.0026551414904894 0.1412472083906251 0.06274863377644352 349.2609382526293 1261791.7620924057 0.020886733377904386 0.018829948837565585 1.7046719136599496e-07 6.7683591942655275 -0.04863790995081718 VQPNEAVY(ph)TK ddPTM_PC-9_AZD4547_30min_R2 1 VQPNEAVYTK 10 0 P11413;P11413-2;P11413-3 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 1 VQPNEAVY(0.698)T(0.302)K 75.566 0.035279000000000005 6031300.0 35668.0 28717.0 46120.0 66012.0 54011.0 44869.0 31885.0 48700.0 40107.0 43669.0 True False 47009.68205951175 37999.208658457654 45508.418665727346 50793.9532752333 46512.50494772316 42063.334336974876 34722.70323057035 41174.53401466946 42226.974139936676 42140.16160180912 1.1155553342133737 0.9017338143484078 1.0799298563623358 1.2053573442644954 1.1037571565868491 0.9981768635450381 0.8239812547154461 0.9770853373495794 1.0020600902993173 1.0 15.362908226255252 -6.953135874670331 5.608217437049937 0.9437481960974313 1.0767825505667175 0.3469165503735536 0.08458027304100563 0.23182005173094536 16.886646444028884 0.03254949652208168 0.02833674525442246 1.1139459666014401e-07 6.953135874670331 0.13303435446928613 VQPNEAVY(ph)TK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VQPNEAVYTK 10 0 P11413;P11413-2;P11413-3 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 1 VQPNEAVY(0.61)T(0.39)K 100.88 0.008972399999999998 0.0 5851.6 10734.0 11043.0 11737.0 13067.0 9547.4 12045.0 10161.0 10265.0 8533.5 True False 6842.160305631833 11799.600581465347 11306.307000810717 11079.413941867406 10506.615152244365 9046.717536762873 10904.01040175174 9894.284516469419 10415.106205527922 10080.555998851163 0.6787483057890461 1.1705307309249704 1.121595574896786 1.09908758436837 1.0422654418508024 0.897442317446963 1.0816873992857559 0.981521705508806 1.033187674044456 1.0 13.299287593254714 VQPNEAVY(ph)TK ddPTM_PC-9_Lapatinib_30min_R1 1 VQPNEAVYTK 10 0 P11413;P11413-2;P11413-3 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 1 VQPNEAVY(0.671)T(0.329)K 105.17 0.0036244 7587500.0 37112.0 33827.0 38753.0 28515.0 44903.0 43413.0 30726.0 33952.0 41584.0 27824.0 True False 36582.77607449273 33748.67565982468 35566.877930906 30612.088223251467 42261.89382269463 41556.327190645825 32316.841936527344 35529.53386786977 36900.37202106706 32633.341326850452 1.1210245285055354 1.0341777546406667 1.0898938473591686 0.938061717819379 1.2950526089071326 1.2734315733845376 0.9903013489439191 1.0887494943288678 1.1307567818899908 1.0 14.99405909204458 -4.420350059059593 20.444761456890983 1.098587302515285 3.921999274212132 0.0036320988585166747 0.11033527402291249 3454.2986272796165 693569.1705669573 0.027563647303516813 3148.473982170528 3.798830716376131e-05 4.420350059059593 2.823411971696847 VQPNEAVYT(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VQPNEAVYTK 10 0 P11413;P11413-2;P11413-3 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 1 VQPNEAVY(0.021)T(0.979)K 118.03 0.0022179 4670000.0 23726.0 23915.0 31592.0 27919.0 37341.0 29079.0 34014.0 28327.0 21801.0 20443.0 True False 27742.343190139592 26289.123151271084 32345.27309332717 26354.78894461927 30024.299104611375 27554.046049346143 30791.947679965415 27583.446264937415 22119.798381560093 24149.15407330103 1.1487915107060063 1.0886146600197468 1.3393956987125961 1.0913338357369942 1.2432857487876077 1.1409942545279264 1.2750735527423118 1.142211697404063 0.9159657648635997 1.0 14.55968503297371 -8.161608811204818 4.7462656291815115 0.9598424884527832 1.1889348229979515 0.5773688323728517 0.07788584956856068 0.14380800493596965 5.0875487663755035 0.053747332123289325 0.01892496917010702 6.892728762435513e-09 8.161608811204818 0.2290923345451683 VQPNEAVYT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 VQPNEAVYTK 10 0 P11413;P11413-2;P11413-3 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 1 VQPNEAVY(0.014)T(0.986)K 124.48 0.0010053 5271600.0 30822.0 26922.0 30329.0 28404.0 24501.0 36629.0 29982.0 28848.0 30159.0 22300.0 True False 30382.472627937455 26859.66376308275 27835.466693325612 30492.924912966326 23059.899350819367 35062.46305636942 31534.3212569473 30188.383394801695 26762.175831650668 26154.525287117795 1.1616526124793443 1.0269604769432488 1.0642696201806328 1.1658756784236255 0.8816791395627944 1.3405887765678226 1.2056927400047013 1.1542317462619267 1.0232330940004546 1.0 14.674772964433023 -5.728770932700907 24.925327053892797 1.1206707211459754 1.0785608485506333 0.0035917465530325154 0.12235444572586417 996.7243066283639 760472.0045438176 0.033480053588827385 0.05798318197966613 1.867364366766084e-06 5.728770932700907 -0.04210987259534216 VQPNEAVYTK ddPTM_PC-9_Lapatinib_30min_R1 2 VQPNEAVYTK 10 0 P11413;P11413-2;P11413-3 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ; 152.07 0.000684 28928000.0 104003.0 93585.0 97536.0 104165.0 97927.0 95911.0 100847.0 86215.0 84230.0 87716.0 False True 102519.89814818543 93368.30968234522 89516.966579848 111825.64158425345 92167.12639188963 91809.11010946095 106068.36421183922 90220.86364333131 74743.13041877832 102877.59372577681 0.9965230954123516 0.9075670056127201 0.8701308354709195 1.0869776161593352 0.895891156217784 0.8924111342862545 1.0310152130362564 0.8769729187466964 0.7265248701093097 1.0 16.650569278431412 -7.986359506580448 24.176617402824014 0.8427579164583842 0.9500898127957502 0.15658532411163972 0.08952339708966603 219.5813972309597 389188.98896916246 0.04668155954716474 0.022404710081410175 1.031906845306171e-08 7.986359506580448 0.10733189633736606 VQPPTPLLPS(ph)VK ddPTM_PC-9_AZD4547_30min_R2 1 VQPPTPLLPSVK 12 0 O60885 O60885 BRD4 Bromodomain-containing protein 4 1 VQPPT(0.153)PLLPS(0.847)VK 105.95 0.0026164 0.0 15965.0 13636.0 23416.0 27660.0 22670.0 21371.0 18302.0 23310.0 20727.0 21504.0 True False 21041.537907370875 18043.57033348641 23105.488540257407 21283.41434274002 19522.661812684157 20034.667991608698 19930.842544328003 19707.97511051222 21822.586904990832 20751.151505308182 1.0139937488282715 0.8695214012037275 1.1134557296421348 1.0256497976652372 0.9407989627799799 0.9654725901106641 0.9604692317546647 0.9497292285428538 1.0516325756384448 1.0 14.340903775040525 -8.264633635734436 24.914779818791622 1.0258162839493463 0.9797546597687823 0.08230257317190581 0.06134652996814161 758.0766598379279 5912720.0337136015 0.051689946061397034 0.015511871389457999 5.437088026195661e-09 8.264633635734436 -0.04606162418056403 VQPQWS(ph)PPAGTQPCR ddPTM_PC-9_AZD4547_30min_R2 3 VQPQWSPPAGTQPCR 15 0 P49589-3;E9PLP0;B4DKY1;P49589-2;P49589;C9JLN0;E9PRS8 P49589-3 CARS Cysteine--tRNA ligase, cytoplasmic 1 VQPQWS(0.959)PPAGT(0.041)QPCR;VQPQWS(0.86)PPAGT(0.14)QPCR;VQPQWS(0.882)PPAGT(0.118)QPCR 130.02 1.3517000000000001e-05 30925000.0 73876.7 72087.8 90535.0 106979.0 96418.0 100945.0 70298.8 101378.0 74686.2 89882.0 True False 97367.95386918036 95388.77159623806 89334.44674548176 82316.644359074 83032.02499582616 94632.89319231361 76555.25701317925 85712.35953468521 78633.96005710076 86735.25853795155 1.1225879245702186 1.0997692657421447 1.0299669160078992 0.9490563093560831 0.9573041735904319 1.0910544891142095 0.8826313347493167 0.9882066529747097 0.9065974020552897 1.0 16.404330958665255 -5.402597922481731 2.34377404891254 0.9684874560896233 1.117960909913162 0.5337523497074261 0.053397271200817616 0.2363064802092145 2.4795455204250794 0.014772567843865903 0.04097505841943927 3.957328269771563e-06 5.402597922481731 0.14947345382353872 VQPQWS(ph)PPAGTQPCR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VQPQWSPPAGTQPCR 15 0 P49589-3;E9PLP0;B4DKY1;P49589-2;P49589;C9JLN0;E9PRS8 P49589-3 CARS Cysteine--tRNA ligase, cytoplasmic 1 VQPQWS(0.999)PPAGT(0.001)QPCR 123.63 3.1523e-05 8943800.0 41496.0 37690.0 38666.0 42710.0 49778.0 48512.0 42100.0 32788.0 35760.0 30761.0 True False 48520.45321664136 41431.61411546756 39587.9440816216 40317.097167688255 40024.35823436291 45967.94531950483 38111.98322239502 31927.34974175764 36282.92234872659 36337.725796057995 1.3352638932044827 1.1401818140188111 1.0894447358595072 1.1095107435716836 1.1014546826346752 1.2650198743172736 1.0488268703521755 0.8786281761535334 0.9984918305664207 1.0 15.14918051058495 -7.511641575558893 7.062581864824464 0.9551296281243599 1.1618340710371005 0.5993691567328162 0.07911096005223334 0.10207982236880885 28.8807430729982 0.035658037402270935 0.02224191665095392 3.078636573869231e-08 7.511641575558893 0.2067044429127406 VQPQWS(ph)PPAGTQPCR ddPTM_PC-9_Lapatinib_30min_R1 4 VQPQWSPPAGTQPCR 15 0 P49589-3;E9PLP0;B4DKY1;P49589-2;P49589;C9JLN0;E9PRS8 P49589-3 CARS Cysteine--tRNA ligase, cytoplasmic 1 VQPQWS(0.991)PPAGT(0.009)QPCR;VQPQWS(0.999)PPAGT(0.001)QPCR;VQPQWS(0.995)PPAGT(0.005)QPCR;VQPQWS(0.963)PPAGT(0.037)QPCR 147.53 2.5944e-05 34704300.0 69782.0 70853.0 79354.0 65479.0 78691.0 76806.0 74553.0 70557.0 75527.0 63769.1 True False 68786.89588354842 70688.94423169522 72829.8204352984 70294.54409154064 74062.55009245843 73521.18642353087 78412.98954936932 73835.33580099203 67020.35392543125 74791.50396801534 0.9197153718551402 0.9451467142835557 0.9737713051798523 0.9398733861750148 0.9902535202946494 0.9830152159391297 1.0484210824654991 0.9872155510145616 0.8960958179700808 1.0 16.190586774269715 -4.911192289711577 0.746164568568114 0.9848663311816785 0.8917367168803957 0.21801786066303352 0.03691721086883668 3.913302061282738 1.8760267260913037 0.016039544576343035 0.2966903423972566 1.2268958862578877e-05 4.911192289711577 -0.09312961430128286 VQQEIDS(ph)DESPVAR ddPTM_PC-9_Lapatinib_30min_R1 1 VQQEIDSDESPVAR 14 0 A0A087WU78;A0A087WWC4;Q6T4R5-4;Q6T4R5-3;Q6T4R5-2;Q6T4R5 A0A087WU78 NHS Nance-Horan syndrome protein 1 VQQEIDS(1)DESPVAR 142.19 1.1374000000000002e-05 0.0 7108.7 7109.4 7681.5 5052.9 7666.4 6471.8 4172.3 6531.0 8558.9 7079.5 True False 7007.328634424075 7092.938621100234 7049.956721447481 5424.507121980273 7215.477424722313 6195.016200502649 4388.321278779312 6834.454102587695 7594.906552787396 8303.182142159209 0.8439329060173848 0.8542434092931682 0.8490668518099217 0.6533046040791359 0.8690014624737544 0.7461014457394114 0.5285107810049975 0.8231126314676295 0.9146982955154555 1.0 13.01944863086754 -8.331720932288354 2.8849184978469817 0.9880326045858134 0.7652011213093912 0.3666726102845401 0.10166257204972765 0.29030319585974634 4.485123632704934 0.10049574300636047 0.027748551761245705 4.658853646514026e-09 8.331720932288354 -0.22283148327642222 VQS(ph)AAPAR ddPTM_PC-9_AZD4547_30min_R2 1 VQSAAPAR 8 0 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;C9K073;C9J2Z7;C9JIH5;C9JWH9;C9JHW9 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 VQS(1)AAPAR 77.192 0.02389 7633200.0 23448.0 28332.0 31491.0 29755.0 34727.0 39433.0 23302.0 30010.0 26372.0 26750.0 True False 30903.97625130174 37489.76493754303 31073.40876414613 22895.44446016738 29905.75548165341 36967.24827631397 25375.83285804454 25372.64406119569 27765.970080494924 25813.49064206631 1.1972025279269998 1.4523322497287046 1.203766247463957 0.8869565444534026 1.158532020962645 1.4320902503620032 0.9830453854501743 0.9829218532672135 1.0756379470526471 1.0 14.655837623324999 -1.5228788355262168 0.18197398270576698 0.9723869551227872 2.4837549315778915 0.2253414176232228 0.15929343649618932 88.12219449555626 1.0004349299531772 0.380297270891211 36.93512639835638 0.029999993766036157 1.5228788355262168 1.5113679764551042 VQS(ph)LPSVPLSCAAYR ddPTM_PC-9_AZD4547_30min_R2 2 VQSLPSVPLSCAAYR 15 0 Q96AD5-2;Q96AD5 Q96AD5-2 PNPLA2 Patatin-like phospholipase domain-containing protein 2 1 VQS(0.909)LPS(0.091)VPLSCAAYR;VQS(0.672)LPS(0.325)VPLS(0.002)CAAY(0.001)R 117.13 0.00013341 45916000.0 57843.0 82864.0 109933.0 134995.0 119555.0 134619.0 82360.0 136385.0 101384.0 110140.0 True False 76235.87079085837 109648.1675061613 108475.21659105376 103873.98840195904 102956.85191951726 126201.25264902762 89689.88044753866 115309.8320655175 106742.95126046178 106284.03212400663 0.71728433017963 1.031652312345749 1.0206163091788856 0.9773244985734483 0.968695389721314 1.187396169744319 0.8438697578098393 1.0849215047748664 1.0043178559119748 1.0 16.697565340300002 -4.759335400786528 24.997103097957755 1.013725171462164 0.7172839507021495 0.5365138012519871 0.08251051061649146 41.19475432343609 489309.54778091033 0.019227697997406423 0.12296330222745344 1.7404622146615917e-05 4.759335400786528 -0.29644122076001456 VQS(ph)LPSVPLSCAAYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VQSLPSVPLSCAAYR 15 0 Q96AD5-2;Q96AD5 Q96AD5-2 PNPLA2 Patatin-like phospholipase domain-containing protein 2 1 VQS(0.96)LPS(0.04)VPLSCAAYR 119.0 0.00010409 8279000.0 23949.0 27235.0 28104.0 29697.0 31670.0 22120.0 33643.0 15717.0 19522.0 23272.0 True False 28003.092685688833 29938.710810155466 28774.105945013536 28033.173368973046 25464.490844997235 20959.988259965507 30456.091485772842 15304.44540353803 19807.472318004504 27491.029378949377 1.0186265599472808 1.0890356413165214 1.0466725544677729 1.0197207599086415 0.9262836430743507 0.7624300993259691 1.107855623227186 0.5567068876386657 0.720506753129136 1.0 14.746673307939105 -6.546526624634875 0.9433657593386473 0.7907218480678017 1.0677872718567958 0.3180983600895626 0.1435987565723588 0.6237007906621206 1.2080151942705435 0.07754130941440696 0.08959162877118841 2.841014009895857e-07 6.546526624634875 0.2770654237889941 VQS(ph)LPSVPLSCAAYR ddPTM_PC-9_Lapatinib_30min_R1 3 VQSLPSVPLSCAAYR 15 0 Q96AD5-2;Q96AD5 Q96AD5-2 PNPLA2 Patatin-like phospholipase domain-containing protein 2 1 VQS(0.989)LPS(0.011)VPLSCAAYR;VQS(0.594)LPS(0.337)VPLS(0.034)CAAY(0.034)R;VQS(0.935)LPS(0.064)VPLS(0.001)CAAYR 199.33 5.846499999999999e-10 35086300.0 81927.0 98782.0 116517.0 85214.0 101679.0 118157.0 110450.0 115921.0 98615.0 68806.0 True False 80758.70595642824 98553.27634814807 106937.42202862687 91480.92182557101 95698.44112860532 113103.70054741997 116168.56056399937 121307.11285041626 87507.94023801287 80699.02542176818 1.000739544676632 1.2212449386230604 1.3251389526667197 1.1336062777394393 1.1858686102892033 1.4015497703508917 1.439528667872406 1.5032041863753938 1.0843741889156449 1.0 16.30026363015694 -6.738708552047487 23.189923935580218 1.3267938828499475 1.1822101257961652 0.07716869453916475 0.1649967831406581 199.23138478502628 203253.65511972355 0.05340580151261025 0.05335424804240784 1.8251200998063905e-07 6.738708552047487 -0.14458375705378224 VQS(ph)PEPPAPER ddPTM_PC-9_AZD4547_30min_R2 4 VQSPEPPAPER 11 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 VQS(1)PEPPAPER;VQS(1)PEPPAPER;VQS(1)PEPPAPER;VQS(1)PEPPAPER 125.82 0.00044194 27092200.0 61860.0 105101.0 106345.0 124826.0 95135.0 90184.0 86603.0 128570.0 85434.0 77941.0 True False 81530.19323206795 139072.84288792548 104934.79581541133 96049.2942424753 81927.14739963436 84544.78022344485 94310.49922775885 108702.46074468286 89949.86682303216 75212.30931339397 1.084000663938514 1.8490702407293202 1.3951811448598124 1.2770422171490303 1.089278445875941 1.1240816961378546 1.253923727229099 1.445274872384817 1.1959460844132557 1.0 16.1986811735284 -5.73172546319642 3.4637562783434657 1.2076774435558073 1.4958091829723394 0.23037049568512946 0.20554236920655553 0.3083456224180508 7.6777758690963465 0.056781692547641684 0.09941145411672374 1.8547036933803713e-06 5.73172546319642 0.28813173941653214 VQS(ph)PEPPAPER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VQSPEPPAPER 11 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 VQS(1)PEPPAPER;VQS(1)PEPPAPER;VQS(1)PEPPAPER 118.76 0.0010316 26720300.0 100426.0 102988.0 110475.0 80096.0 164983.0 73486.0 90238.0 94296.0 76129.0 75860.0 True False 117426.13829608707 113211.96801601931 113109.14297877044 75608.48079473563 132655.76549037485 69632.2647952905 81690.00337345578 91820.82991487072 77242.24260308177 89612.8174925703 1.3103721273558075 1.2633457041500293 1.2621982674314216 0.843723955013514 1.4803213335120635 0.7770346557964616 0.9115883827693354 1.0246394710498135 0.861955295730835 1.0 16.451417478020396 -6.777307647697624 24.99999953683182 0.9163675859243877 1.2138418434480007 0.4866050255112305 0.16224066091857586 224.57703310304387 353812.44870548317 0.0559817968612529 0.04952869551010592 1.669907257967235e-07 6.777307647697624 0.297474257523613 VQS(ph)PEPPAPER ddPTM_PC-9_Lapatinib_30min_R1 2 VQSPEPPAPER 11 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 VQS(1)PEPPAPER;VQS(1)PEPPAPER 93.348 0.0071508 17613000.0 36223.0 51697.0 45108.0 21422.0 37532.0 34755.0 32271.0 31849.0 51201.0 26170.0 True False 35706.45337751534 51577.29877275421 41399.39436191537 22997.445341697126 35324.441550751064 33268.60966786207 33941.83447678428 33328.82081049081 45434.204209567484 30693.449630666924 1.16332487247832 1.6804008475222507 1.348802264329121 0.7492623220401905 1.1508788349243466 1.0838993357925533 1.1058331626195506 1.0858610293575732 1.4802573433835389 1.0 14.90564317867339 -5.539716947146884 24.921029774472085 1.0958658320411598 1.4450476290248278 0.3209697676514761 0.20376677972117768 227.4068991669779 336567.47685608175 0.05342363912989467 0.09255990907752919 2.8859117927946425e-06 5.539716947146884 0.3491817969836679 VQS(ph)PKPITGGLGAFTK ddPTM_PC-9_AZD4547_30min_R2 2 VQSPKPITGGLGAFTK 16 1 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 VQS(0.996)PKPIT(0.004)GGLGAFTK;VQS(0.966)PKPIT(0.034)GGLGAFTK 56.882 0.028205 20107400.0 86557.0 74950.0 95042.0 108239.0 90923.0 114908.0 81869.0 91260.0 77035.0 86675.0 True False 114080.32550255579 99176.12177286639 93781.68098066031 83286.17082587989 78299.91089522194 107722.78459500117 89155.182398732 77157.86394617525 81106.9128299306 83640.53463181657 1.3639358715810985 1.1857423223014663 1.1212467901297476 0.9957632527398758 0.9361479005352619 1.2879255861908825 1.0659327178047195 0.9224936723064018 0.9697082065168653 1.0 16.35191466323932 -4.76708634922921 1.19196438109885 1.0313192441894443 1.5263051915918262 0.5327217674200879 0.09855280803624938 1.3823190491601802 1.6220485711872952 0.03249455351415276 0.8631186756042591 1.709675352617099e-05 4.76708634922921 0.4949859474023819 VQS(ph)PKPITGGLGAFTK ddPTM_PC-9_Lapatinib_30min_R1 1 VQSPKPITGGLGAFTK 16 1 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 VQS(0.997)PKPIT(0.003)GGLGAFTK 69.03 0.010477 7537400.0 52522.0 46044.0 45606.0 46487.0 49423.0 44724.0 47222.0 43922.0 51287.0 34434.0 True False 51773.02664864483 45937.38794693493 41856.45072425096 49905.80905608598 46516.036309356525 42811.25877673608 49666.924100979486 45962.776465144176 45510.517983947364 40385.87101957907 1.2819588965543238 1.1374618594870587 1.0364132224351172 1.2357244698744183 1.1517898496433456 1.060055353417565 1.2298094072776333 1.1380905080111166 1.1268920747526745 1.0 15.301563034526417 -14.522878743427304 0.253114779212676 0.05744118021743194 1.165428990878686 0.3081004132014237 0.07175887925545434 245.43525426652621 2.4229576906685204 119.8455768085606 0.10056521652059487 3.0000000128003014e-15 14.522878743427304 1.107987810661254 VQSGNINAAK ddPTM_PC-9_Lapatinib_30min_R1 1 VQSGNINAAK 10 0 P49368-2;P49368;Q5SZX6;E9PM09;Q5SZX9;Q5SZW8;E9PRC8 P49368-2 CCT3 T-complex protein 1 subunit gamma 0 91.584 0.029838 0.0 13590.0 21495.0 26154.0 18470.0 30567.0 21670.0 15945.0 16896.0 16392.0 11042.0 False True 13396.204107899232 21445.229648148863 24003.719077359565 19828.3454141138 28769.10915703422 20743.22461523725 16770.55408051581 17681.04984188053 14545.76034458761 12950.59498745984 1.0344083897976022 1.6559262079398238 1.853483882447297 1.5310760187708548 2.2214507661533367 1.6017198156009878 1.294963984029681 1.3652693068543358 1.1231731328693688 1.0 13.660730760529932 -7.310484794881365 3.1052627382921005 1.2052198988784213 1.6833566867315728 0.37307599163003635 0.28982888662449435 0.3035236512206041 5.866578516301405 0.1349306481104783 0.08894579211436004 4.892323933887988e-08 7.310484794881365 0.4781367878531515 VQSLEGEKLS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 VQSLEGEKLSPK 12 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 VQSLEGEKLS(1)PK;VQSLEGEKLS(1)PK 90.725 0.032780000000000004 114148000.0 92803.0 82198.0 56644.0 81961.0 76413.0 67130.0 86889.0 75774.0 76249.0 73512.0 True False 122312.42357768507 108766.89603050127 55892.8635494679 63066.157734827044 65804.37393439071 62932.35048788976 94621.95267370337 64064.86941329704 80279.36647458139 70938.36725531155 1.724206918062762 1.5332590844534457 0.7879073865388816 0.8890274780056336 0.9276274106726579 0.8871412315058276 1.3338614396515942 0.903106060824936 1.1316776743063597 1.0 16.114278504581883 -5.133794532272667 4.7080354847679375 0.9842424266673787 1.679611217186358 0.7577305488427218 0.1474453939466064 0.10178677393661852 3.378034323043205 0.03883040444560325 0.11300675993488285 7.3486145397156375e-06 5.133794532272667 0.6953687905189793 VQSLPS(ph)VPLSCAAYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VQSLPSVPLSCAAYR 15 0 Q96AD5-2;Q96AD5 Q96AD5-2 PNPLA2 Patatin-like phospholipase domain-containing protein 2 1 VQS(0.333)LPS(0.667)VPLSCAAYR 112.12 0.00035141 7248300.0 29506.0 40911.0 46073.0 46084.0 43895.0 36568.0 38490.0 28899.0 34876.0 25198.0 True False 34500.78302993589 44972.37370862019 47171.555052825526 43502.06288634386 35294.08985289404 34650.30970571513 34843.94855653171 28140.431871021538 35385.99552109028 29766.19793274176 1.1590591149024865 1.5108538151307584 1.584735650801357 1.4614584968036222 1.1857103796945392 1.1640824865845907 1.1705878135750956 0.9453821389821527 1.1887979647601192 1.0 14.861387335963144 -6.408874847220194 2.6926671922564966 1.0960134553739602 1.4473881683123515 0.6123543768985206 0.1258021164923483 0.19094536618559432 2.6919926840575497 0.04335086591910805 0.04965192983722579 3.9005437437223796e-07 6.408874847220194 0.3513747129383913 VQT(ph)LNEQDWER ddPTM_PC-9_AZD4547_30min_R2 1 VQTLNEQDWER 11 0 A0A2R8Y7R9;Q13136-2;Q13136 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 VQT(1)LNEQDWER 113.25 0.0038787 1039000.0 4577.4 3973.6 5642.5 4655.3 5114.6 5336.3 3650.7 5114.6 4229.6 3777.9 True False 6032.917984165328 5257.988492016833 5567.676763255991 3582.092508668026 4404.526074422337 5002.620317421809 3975.605227656994 4324.256091815777 4453.168021100465 3645.6368709032663 1.65483239219889 1.442268848546641 1.5272164947894298 0.982569749954417 1.208163684533683 1.3722212317274287 1.0905104837476511 1.1861455885331693 1.2215061946082193 1.0 11.831955151404646 -5.7412236211198655 24.964045772585962 1.168349679586907 1.5315224738483586 0.6960337913740368 0.11764180135354703 139.1891098145762 171880.56282379708 0.0315608975916418 0.05457835714332742 1.8145810823038402e-06 5.7412236211198655 0.36317279426145155 VQT(ph)LNEQDWER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VQTLNEQDWER 11 0 A0A2R8Y7R9;Q13136-2;Q13136 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 VQT(1)LNEQDWER 128.95 0.00069458 1434500.0 5357.2 9203.9 7278.3 5143.7 4743.0 3842.7 3410.0 4114.6 5332.4 3734.8 True False 6264.068150476938 10117.602365543959 7451.842275106463 4855.515165100403 3813.643197910384 3641.182047313266 3086.9801137379345 4006.596109779064 5410.376262090313 4411.889675339467 1.419815229172737 2.293258243082761 1.6890364046859558 1.1005522627278301 0.8644013061403101 0.8253112192868014 0.699695672580573 0.9081360606486112 1.22631721557589 1.0 12.107180999700477 -5.770905889540311 3.052872859905513 0.9057582149479447 1.8854479766134888 0.7394385034734827 0.23512453203592115 0.1123719770625969 2.152388768850921 0.06620896214164726 0.11472046065299348 1.6947049987284248e-06 5.770905889540311 0.9796897616655441 VQT(ph)LNEQDWER ddPTM_PC-9_Lapatinib_30min_R1 1 VQTLNEQDWER 11 0 A0A2R8Y7R9;Q13136-2;Q13136 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 VQT(1)LNEQDWER 96.464 0.014166 1003500.0 2772.0 4035.1 4416.3 2710.6 4114.0 4535.2 2780.9 4058.6 3195.8 4489.1 True False 2732.4707716774587 4025.7569738658067 4053.2088614109907 2909.9465662965263 3872.022608435199 4341.240068067559 2924.8813949517985 4247.177372647746 2835.855350734084 5265.034953650244 0.5189843554187688 0.764621129642217 0.7698351287489373 0.5526927345998079 0.7354220138179196 0.8245415474512248 0.5555293403938337 0.8066760069091625 0.5386204224091595 1.0 12.362227393746029 -10.90420632546665 3.5514408674935827 1.00201467054137 0.6826495864513551 0.41612344706022975 0.1154125261396337 72455068.84713285 97451747.48487054 1470617.0976929197 0.02704491651820981 1.2467910456050368e-11 10.90420632546665 -0.31936508409001485 VQT(ph)PEVDVK ddPTM_PC-9_AZD4547_30min_R2 2 VQTPEVDVK 9 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VQT(1)PEVDVK;VQT(1)PEVDVK 112.5 0.0052913000000000005 87896000.0 353440.0 415070.0 416820.0 580020.0 579060.0 537670.0 528110.0 742470.0 618510.0 582240.0 True False 465826.5679913044 549233.2603637576 411292.6944546505 446305.35021966975 498667.5143031717 504049.4099035246 575110.766915369 627738.3217632767 651203.1758868087 561855.9548200641 0.8290853981257288 0.9775339313430451 0.7320251586305037 0.7943412299734373 0.8875362270795392 0.8971150088903975 1.0235911214993703 1.1172584652312025 1.1590215789300626 1.0 19.099840782990796 -7.285060264229173 1.819523161814154 1.1048063677450979 0.842048541562066 0.7155052710806008 0.07009850551066013 0.1919754521137717 1.2391466343119333 0.03838992794754247 0.023458614772521414 5.1872805340619336e-08 7.285060264229173 -0.2627578261830319 VQT(ph)PEVDVK ddPTM_PC-9_Lapatinib_30min_R1 2 VQTPEVDVK 9 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VQT(1)PEVDVK;VQT(1)PEVDVK 145.14 0.0012468 96654000.0 787970.0 683790.0 649740.0 578070.0 566460.0 511970.0 530040.0 401440.0 480430.0 488140.0 True False 776733.4033040013 682206.7262669315 596320.885268929 620583.1961849903 533141.9365032092 490074.2365603601 557482.8776943622 420092.3679287718 426318.91424781777 572514.3485943351 1.3567055659147664 1.1915976043952756 1.041582427991621 1.0839609482429151 0.9312289514004408 0.8560034133006693 0.9737448136682008 0.7337674050619044 0.7446431959208298 1.0 19.126952325526716 -4.753610738778665 0.4909085978596708 0.8277214398305855 1.7224129910919115 0.7744556466514555 0.08682182140252073 2.1564393058452125 0.3927157988922791 0.05687621059075426 1.1301562827852545 1.7635560259942284e-05 4.753610738778665 0.8946915512613259 VQT(ph)PLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VQTPLLR 7 0 Q9UHD8;Q9UHD8-7;Q9UHD8-5;Q9UHD8-2;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 SEPT9 Septin-9 1 VQT(1)PLLR 77.192 0.038636000000000004 0.0 6620.4 9406.1 9688.3 8965.4 11393.0 10843.0 14540.0 11367.0 8861.3 5929.9 True False 7741.102961139691 10339.875445250724 9919.305815082354 8463.097704218966 9160.623435334815 10274.37399198942 13162.665939515995 11068.628294332048 8990.87974856742 7004.943928937425 1.1050913525747426 1.4760825425792055 1.4160435708993615 1.208160663393451 1.3077368681699617 1.466731796316881 1.879053718780106 1.5801166157244373 1.2835048845182178 1.0 12.77415778731423 -6.81376400797505 5.369255101026716 1.5082209745266506 1.3131029139057215 0.04728151961670346 0.23315504719526317 0.4152122560447133 25.534879064724706 0.08203505294334076 0.07337688172120727 1.5354511075668687e-07 6.81376400797505 -0.19511806062092907 VQT(ph)TPPPAVQGQK ddPTM_PC-9_AZD4547_30min_R2 1 VQTTPPPAVQGQK 13 0 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 1 VQT(0.943)T(0.057)PPPAVQGQK 109.44 0.0019228 8890700.0 15033.0 14291.0 16832.0 25083.0 20745.0 20707.0 16492.0 23413.0 16577.0 20874.0 True False 19813.181294175178 18910.286274263286 16608.796682166572 19300.50187848691 17864.914834765455 19412.188016575794 17959.756050762637 19795.058827216748 17453.22637738377 20143.207613551116 0.9836159997102986 0.9387922041542979 0.8245358435859635 0.9581642729781882 0.8868952342400043 0.9637088783971259 0.891603581481254 0.9827163184228834 0.8664571557929189 1.0 14.298005816602812 -10.981836056966602 3.0307218088019585 1.0017901638629327 0.9216436705339672 0.17708606962974105 0.05055006310595638 20549516.633709703 22823838.003873695 308300.7488862154 0.011803740040245887 1.0427109709772558e-11 10.981836056966602 -0.0801464933289655 VQT(ph)TPPPAVQGQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VQTTPPPAVQGQK 13 0 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 1 VQT(0.734)T(0.266)PPPAVQGQK 88.021 0.016651 78634000.0 41195.0 39366.0 37714.0 42649.0 50254.0 41181.0 45811.0 41511.0 41656.0 30817.0 True False 48168.49986166235 43273.99631916948 38613.24479114147 40259.51479992359 40407.08945135747 39021.39586499275 41471.450437081694 40421.3802345401 42265.14019459046 36403.87815276222 1.323169461768113 1.1887194033992219 1.060690419551127 1.1059127994820195 1.1099666162433712 1.0719021666111122 1.1392041876157901 1.1103591783523492 1.1610065284042685 1.0 15.15180453035052 -4.886203560981519 2.7866557136022747 1.10078307717153 1.3399855459926315 0.730714100199036 0.04284548227515958 0.16942105042277136 2.1250198836436476 0.010505183256723434 0.08409804217019165 1.299560309921399e-05 4.886203560981519 0.23920246882110163 VQT(ph)TPPPAVQGQK ddPTM_PC-9_Lapatinib_30min_R1 3 VQTTPPPAVQGQK 13 0 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 1 VQT(0.86)T(0.14)PPPAVQGQK;VQT(0.5)T(0.5)PPPAVQGQK;VQT(0.673)T(0.327)PPPAVQGQK 88.803 0.015702 122108200.0 124597.0 119540.0 130535.0 115237.0 121016.0 116328.0 99984.0 103521.0 115507.0 85994.0 True False 122820.22393170865 119263.21247451546 119802.9161796713 123711.91339936311 113898.07680661017 111352.9226138127 105160.6822945307 108330.96358199035 102497.385317367 100857.94832019773 1.2177545347421348 1.1824869974142822 1.187838124560379 1.2265955778379507 1.1292920260980666 1.1040569877576347 1.0426613275998131 1.0740944604392282 1.0162549112338126 1.0 16.621965257448473 -6.860244122135465 1.023977107556153 1.0264491123210857 1.2055886406492269 0.9156633817451044 0.02304698946714182 0.14120619842870577 0.3134322405567735 0.013587136921452685 0.011177649945498669 1.3796085520960312e-07 6.860244122135465 0.17913952832814117 VQT(ph)TPSKPGGDR ddPTM_PC-9_Lapatinib_30min_R1 1 VQTTPSKPGGDR 12 1 Q12834 Q12834 CDC20 Cell division cycle protein 20 homolog 1 VQT(0.973)T(0.024)PS(0.003)KPGGDR 65.695 0.029568 220140000.0 52012.0 40670.0 56327.0 49010.0 52835.0 45228.0 40544.0 39572.0 51223.0 40960.0 True False 51270.299342167345 40575.83111375733 51696.011488507764 52614.35889256722 49727.34917760665 43293.703871617465 42643.169936684404 41410.65958468846 45453.72633789725 48039.881424230676 1.0672445023210921 0.8446280446748027 1.0761061425608138 1.0952224970736344 1.0351263929749177 0.901203387437603 0.8876618482904031 0.8620058658971101 0.9461664973005324 1.0 15.551944969625355 -6.763594025487309 24.993414270344562 0.9087987666044465 1.020607753835973 0.32806242108698347 0.07376321470653517 67.51518798490248 783153.2895588132 0.026047725342469772 0.02409522436868964 1.7234789145419342e-07 6.763594025487309 0.11180898723152655 VQTESSTGS(ph)VGSNR ddPTM_PC-9_AZD4547_30min_R2 1 VQTESSTGSVGSNR 14 0 Q9BRX2 Q9BRX2 PELO Protein pelota homolog 1 VQTES(0.002)S(0.001)T(0.007)GS(0.989)VGSNR 129.05 0.00048082 0.0 3434.0 3424.3 5310.3 6519.8 4354.0 4471.3 4702.4 6421.0 4727.1 5493.0 True False 4525.940568362772 4531.138009163795 5239.881952311615 5016.760839905868 3749.522255510669 4191.708904163584 5120.90449024413 5428.781989901286 4976.964855434083 5300.691741939075 0.8538396097538608 0.854820130986571 0.9885279520885298 0.9464351228375072 0.7073647059768535 0.7907852612893486 0.9660823038864026 1.024164817385769 0.9389274264066962 1.0 12.371964928780258 -7.406398059970681 6.39475959329386 0.9877584619429164 0.8604397998259925 0.4034756237551085 0.07488106661671223 0.28338734835996243 13.865277774922841 0.03534853979953195 0.023594399581758966 3.922852149060603e-08 7.406398059970681 -0.1273186621169239 VQTESSTGS(ph)VGSNR ddPTM_PC-9_Lapatinib_30min_R1 2 VQTESSTGSVGSNR 14 0 Q9BRX2 Q9BRX2 PELO Protein pelota homolog 1 VQT(0.001)ES(0.298)S(0.17)T(0.098)GS(0.423)VGS(0.009)NR;VQT(0.001)ES(0.03)S(0.03)T(0.017)GS(0.922)VGS(0.001)NR 108.14 0.00097563 2243600.0 7320.6 7627.6 10439.3 9723.4 9725.4 9757.599999999999 9615.2 7883.8 11491.8 9515.6 True False 7216.206901566379 7609.938760838343 9581.021050863337 10438.491272311534 9153.371092872065 9340.290194076555 10113.028008465079 8250.110129226901 10197.472469981209 11160.358781259994 0.6465927344274568 0.6818722327831103 0.858486831709334 0.9353186108890522 0.8201681749015113 0.8369166598622598 0.9061561735314863 0.7392334145278681 0.9137226382994403 1.0 13.446095786969634 -5.2384015860095685 4.276808770314081 0.8675283549877009 0.6567544892481466 0.6117864151858731 0.06751822882226859 0.13099704024753303 5.868345575858518 0.016845295092863664 0.04537881997166554 5.775617371802735e-06 5.2384015860095685 -0.21077386573955426 VQTLSNQPLLKS(ph)PAPPLLHVAALGQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VQTLSNQPLLKSPAPPLLHVAALGQK 26 1 Q8N163-2;Q8N163;H0YC69;E5RGU7;E5RFJ3;H0YC58 Q8N163-2 CCAR2 Cell cycle and apoptosis regulator protein 2 1 VQT(0.006)LS(0.013)NQPLLKS(0.981)PAPPLLHVAALGQK 46.273 0.016024 1827900.0 6921.5 9054.4 7275.5 9610.5 10194.0 10384.0 13145.0 13313.0 12603.0 9914.5 True False 8093.173244143612 9953.260993555046 7448.975512487399 9072.054842661393 8196.558878241294 9839.444760012742 11899.81043844139 12963.547856289484 12787.295032466482 11711.920366861177 0.6910201735185296 0.8498402210552721 0.6360165779101641 0.7746001132598825 0.6998475588540901 0.8401222388647215 1.0160426356818346 1.1068678278388726 1.0918188163785738 1.0 13.515690028966672 -7.190500472723468 2.329417786424401 1.0741213118180863 0.73424612511991 0.8668626146406384 0.05991910020469899 0.09777979905205077 1.038794062092337 0.026257855451027236 0.01819209372890862 6.449106178915386e-08 7.190500472723468 -0.3398751866981763 VQTT(ph)PPPAVQGQK ddPTM_PC-9_AZD4547_30min_R2 2 VQTTPPPAVQGQK 13 0 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 1 VQT(0.044)T(0.956)PPPAVQGQK;VQT(0.001)T(0.999)PPPAVQGQK 89.44 0.014928 130541300.0 67182.0 70622.0 82012.0 116396.0 96682.0 80638.0 80738.0 102309.0 65350.0 83225.0 True False 88544.47852759117 93449.18041151925 80924.46729431109 89562.70050027354 83259.37315279814 75595.69311250505 87923.52558976911 86499.49487693657 68804.26758533073 80311.3180817184 1.1025155686960006 1.163586685458615 1.0076346550802315 1.1151940055216336 1.0367078407065868 0.9412831829703615 1.0947837451790434 1.0770523625190858 0.8567194416523084 1.0 16.29331569717675 -5.126515374481051 0.3248339607567297 0.975247261903194 1.225565099618044 0.3169296780935176 0.07167223220485522 7.374965539570889 0.7485165996489844 0.07725758185689945 0.7171432063762146 7.472821791485647e-06 5.126515374481051 0.25031783771485006 VQTT(ph)PPPAVQGQK ddPTM_PC-9_Lapatinib_30min_R1 1 VQTTPPPAVQGQK 13 0 Q2M2I8;Q2M2I8-2;E9PG46 Q2M2I8 AAK1 AP2-associated protein kinase 1 1 VQT(0.381)T(0.619)PPPAVQGQK 102.66 0.0041413000000000005 10315000.0 22744.0 19341.0 22387.0 18965.0 23241.0 18143.0 16062.0 18440.0 21006.0 15760.0 True False 22419.666389261216 19296.217102807503 20546.427276319042 20359.749365385393 21874.01007356404 17367.06618339868 16893.61176803042 19296.78971852964 18640.08307701364 18484.09500112002 1.212916639300043 1.0439362652939337 1.111573343194463 1.1014739625689935 1.1833963238253544 0.9395681088171397 0.9139539570104338 1.0439672441285535 1.0084390431819448 1.0 14.173996789081732 -6.766333948951902 24.99997953348422 0.9797316307995481 1.123159624056936 0.6503995687427877 0.05465035236118316 82.98212308211878 423844.5513689097 0.019277009192188724 0.017530832084495865 1.7126398736835101e-07 6.766333948951902 0.14342799325738786 VQTT(ph)PSKPGGDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VQTTPSKPGGDR 12 1 Q12834 Q12834 CDC20 Cell division cycle protein 20 homolog 1 VQT(0.055)T(0.944)PS(0.002)KPGGDR 115.34 0.0047552 0.0 9660.5 9599.6 10701.0 12761.0 15437.0 11501.0 14114.0 12520.0 10016.0 7820.2 True False 11295.831846427707 10552.584846453772 10956.152423768497 12046.042541720199 12412.230665431716 10897.867313646626 12777.019743488921 12191.363266036518 10162.465051589641 9237.94035533086 1.2227651848725476 1.1423092638137982 1.1859951463581515 1.3039749206400635 1.3436145058318216 1.1796858276269218 1.3831026453982023 1.319705778247567 1.1000790934664644 1.0 13.173355516133062 -8.465872587994747 4.15216088661569 1.0014411501104172 1.2586848411717766 0.5766623821812127 0.07431223569688546 0.1464745948085522 5.148911693978859 0.07737981198070311 0.020270447216603482 3.4207978612966507e-09 8.465872587994747 0.25724369106135936 VQTT(ph)PSKPGGDR ddPTM_PC-9_Lapatinib_30min_R1 1 VQTTPSKPGGDR 12 1 Q12834 Q12834 CDC20 Cell division cycle protein 20 homolog 1 VQT(0.154)T(0.836)PS(0.011)KPGGDR 77.633 0.012508 209030000.0 72385.0 57778.0 67626.0 62365.0 67753.0 57323.0 51324.0 51715.0 62218.0 52074.0 True False 71352.77662621667 57644.21859086972 62066.05132390913 66951.53014354118 63767.901747523145 54871.42891643956 53981.30558973932 54117.86769488941 55210.35365541435 61074.92151575659 1.1682827395497923 0.9438279601554331 1.016228097941916 1.0962196672863262 1.0440930608657728 0.8984281527448773 0.8838538675127531 0.8860898442731139 0.9039774802030772 1.0 15.898292484109906 -6.758666715043127 23.821285414166287 0.9054369624035433 1.0479017253048641 0.5543715078234325 0.06205549836972658 29.725768243338603 255388.7229853434 0.020421314712851493 0.019535756852517006 1.74314407858202e-07 6.758666715043127 0.14246476290132082 VQVAALQAS(ph)PPLDQDDR ddPTM_PC-9_AZD4547_30min_R2 4 VQVAALQASPPLDQDDR 17 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IU26;B1AN86;U3KQJ2 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 VQVAALQAS(1)PPLDQDDR;VQVAALQAS(1)PPLDQDDR;VQVAALQAS(1)PPLDQDDR;VQVAALQAS(1)PPLDQDDR 204.71 2.0884999999999997e-24 13007800.0 51220.0 46759.5 65448.0 73945.0 69459.0 73868.0 59641.0 90809.0 64730.0 65191.0 True False 67506.89455781631 61873.59394313998 64580.11675703649 56898.12268886158 59815.81679961317 69249.02228272658 64948.933460073604 76776.55563322623 68151.49565108593 62908.6829325961 1.07309343338418 0.9835461665829951 1.0265692070875376 0.9044557926896264 0.950835624133209 1.1007863947322483 1.0324319383647491 1.2204444927815283 1.0833400490057514 1.0 15.94097153750065 -6.771369967561066 24.790745840690217 1.0977428458137861 0.985003991214903 0.3443097502158774 0.06799751105338343 195.36070751971644 487695.8232283585 0.02395473957742042 0.021377997986550528 1.6928950395454432e-07 6.771369967561066 -0.11273885459888311 VQVAALQAS(ph)PPLDQDDR ddPTM_PC-9_Lapatinib_30min_R1 3 VQVAALQASPPLDQDDR 17 0 Q9UDY2-7;Q9UDY2;Q9UDY2-3;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;A0A3B3IRI3;Q9UDY2-6;A0A3B3ISZ5;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISF1;Q9UDY2-5;A0A3B3IRV6;A0A3B3IU26;B1AN86;U3KQJ2 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 VQVAALQAS(1)PPLDQDDR;VQVAALQAS(1)PPLDQDDR;VQVAALQAS(1)PPLDQDDR 132.51 2.3869e-05 8282100.0 53245.0 83992.0 96039.0 83866.0 104103.0 103097.0 90029.0 91402.0 101700.0 81415.0 True False 52485.71653606286 83797.5216844532 88143.04414126085 90033.78540877484 97979.86621437281 98687.78164084522 94690.26110471993 95648.8705994059 90245.47505152265 95487.47427133155 0.5496607480361514 0.8775760624512815 0.9230848843147615 0.9428858192744755 1.0261017684472313 1.0335154678028227 0.9916511231164592 1.0016902355969302 0.9451027555204409 1.0 16.54302387718144 -4.430234556845668 1.2442989546404175 0.9930644914854726 1.1362884121689885e-16 0.9445594793131151 0.03173289635785877 0.6696034780655576 0.5032757057954229 0.009885605111282622 1.0537023151568914 3.7133462189167626e-05 4.430234556845668 -0.9930644914854725 VQVQDNEGCPVEALVK ddPTM_PC-9_Lapatinib_30min_R1 2 VQVQDNEGCPVEALVK 16 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 276.32 1.0539999999999998e-81 15623200.0 43328.0 45421.0 55392.0 49084.0 51300.0 47903.0 53931.0 38644.0 43769.0 53767.0 False True 42710.13477461792 45315.83046515792 50837.88357930337 52693.801099424025 48282.63485968054 45854.30035734702 56723.283293590364 40439.541316857874 38839.27431199702 63060.554309975865 0.6772876521933997 0.7186081847997517 0.8061756534744109 0.8356063735248221 0.7656550975169983 0.7271471184973884 0.8995049903108293 0.6412810949627276 0.6159044229310372 1.0 15.944450231092082 -11.6317022825032 2.548310840564244 1.475918500219104 0.7486908905627184 0.45965645670465627 0.08338352023774502 15352317.55104714 2390747.4735974367 42645069.129726194 0.0215579232554816 2.33505824256366e-12 11.6317022825032 -0.7272276096563856 VRAS(ph)LDSAGGSGSSPILLPTPVVGGPR ddPTM_PC-9_AZD4547_30min_R2 2 VRASLDSAGGSGSSPILLPTPVVGGPR 27 1 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 VRAS(0.566)LDS(0.421)AGGS(0.007)GS(0.005)S(0.001)PILLPTPVVGGPR;VRAS(0.908)LDS(0.089)AGGS(0.001)GS(0.002)S(0.001)PILLPTPVVGGPR 113.39 1.5017e-11 17306600.0 23481.9 21003.0 26063.1 32459.0 26115.8 22449.5 19555.4 34016.0 22100.5 25021.3 True False 30948.655746137967 27791.809013949467 25717.486264672993 24976.079036550927 22490.07196152169 21045.72921611619 21295.792716170487 28759.608809917805 23268.68731093503 24145.311902890993 1.2817666580829046 1.1510229863968693 1.0651130276595746 1.0344069746127598 0.9314467359946957 0.8716279707116278 0.8819845774541714 1.1911052930517054 0.9636937971444882 1.0 14.559455479541596 -5.02282648366404 1.1466878278033408 0.976618479480619 1.3489749392075037 0.5717316233924683 0.08449879592780046 0.883189878358003 1.2967260420641324 0.029174182649371404 0.35836109948696554 9.487974664496753e-06 5.02282648366404 0.3723564597268847 VRAS(ph)LDSAGGSGSSPILLPTPVVGGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VRASLDSAGGSGSSPILLPTPVVGGPR 27 1 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 VRAS(0.943)LDS(0.055)AGGS(0.001)GS(0.001)SPILLPTPVVGGPR;VRAS(0.97)LDS(0.029)AGGS(0.001)GSSPILLPTPVVGGPR 93.553 1.6051e-08 14198300.0 24552.6 23064.0 26289.2 21264.6 26508.5 21846.9 23337.5 23185.1 15137.900000000001 12297.0 True False 28708.870244045414 25353.64149533414 26916.0342303462 20073.213402763366 21314.34971785947 20701.210104730573 21126.803051131697 22576.515691644046 15359.263149406841 14526.348757001564 1.9763307851333258 1.745355417211357 1.8529111947262675 1.3818485111813295 1.4672888607046664 1.4250800700866268 1.4543780687455117 1.554176900837685 1.0573381794928902 1.0 13.826384502194733 -1.5228787452831543 0.13258458537929343 0.878199361631877 4.4753221027136405 0.782039816455242 0.13869165998203972 39.03213278908728 0.3501127078572085 0.7180092283845534 26.324354663484822 0.02999999999980543 1.5228787452831543 3.5971227410817637 VRAS(ph)LDSAGGSGSSPILLPTPVVGGPR ddPTM_PC-9_Lapatinib_30min_R1 2 VRASLDSAGGSGSSPILLPTPVVGGPR 27 1 Q9BST9;Q9BST9-3;Q9BST9-2 Q9BST9 RTKN Rhotekin 1 VRAS(0.835)LDS(0.164)AGGS(0.001)GSSPILLPTPVVGGPR;VRAS(0.968)LDS(0.027)AGGS(0.001)GS(0.004)S(0.001)PILLPTPVVGGPR 93.553 1.6051e-08 12429300.0 38489.0 26711.0 33614.0 35406.0 31335.0 26246.0 23345.9 22430.2 32113.0 31011.0 True False 37940.13980198184 26649.152320618938 30850.386673792316 38009.8753509536 29491.936906980318 25123.519762414267 24554.636469633995 23472.38897747091 28496.095775118498 36371.21003043991 1.0431365844091758 0.732699085301689 0.848208972095592 1.0450539126727503 0.810859382525295 0.690752926322435 0.6751118934201984 0.6453562847600155 0.7834794539766331 1.0 15.150509303029969 -6.518096068245547 15.803250515469628 0.733673075189119 0.902758224894442 0.24716417125635504 0.12583004109579812 2.2971990305792667 7590.992213919424 0.039652164788935344 0.04123519625600622 3.033220145575431e-07 6.518096068245547 0.16908514970532307 VRAS(ph)LSDLSSLDDVEGMSVR ddPTM_PC-9_Lapatinib_30min_R1 1 VRASLSDLSSLDDVEGMSVR 20 1 H7BYJ1;A0A087WTM5;Q969K3;Q969K3-2 H7BYJ1 RNF34 E3 ubiquitin-protein ligase RNF34 1 VRAS(0.765)LS(0.233)DLS(0.001)SLDDVEGMSVR 57.316 0.029263 3212900.0 11196.0 8985.4 9602.3 8081.5 9173.0 9756.3 8955.5 7025.0 10895.0 8356.2 True False 11036.342986905061 8964.594858361334 8812.8359599499 8675.8404690937 8633.462174811888 9339.045792046109 9419.171970401962 7351.407146023354 9667.890370563817 9800.558036063387 1.1260933251243779 0.9147024919779123 0.8992177718371813 0.8852394360779221 0.880915366558016 0.9529095953190585 0.9610852704245995 0.7501008737433292 0.986463253927849 1.0 13.258648182149184 -4.7614401651966025 5.959590273415949 0.9063824492298318 1.134413175017099 0.4641492773632171 0.06775345965384587 0.11241316732628324 15.141629048428792 0.016006308343316195 0.10489046401248833 1.7320476467026546e-05 4.7614401651966025 0.22803072578726713 VRDLT(ph)IQK ddPTM_PC-9_AZD4547_30min_R2 2 VRDLTIQK 8 1 P14868;C9J7S3;C9JLC1;C9JQM9;H7C278 P14868 DARS Aspartate--tRNA ligase, cytoplasmic 1 VRDLT(1)IQK;VRDLT(1)IQK 79.65899999999999 0.014705000000000001 7586900.0 29958.0 24892.0 38484.0 32779.0 34470.0 33993.0 32414.0 31849.0 31855.0 31673.0 True False 39484.020834889896 32937.85221040948 37973.677015001114 25222.307980501646 29684.435495510483 31867.41233628534 35298.783205761574 26927.46886721166 33538.79026672857 30564.137910510908 1.2918414695842433 1.077663381406294 1.2424259151749897 0.8252255651492717 0.971217823398909 1.0426406407924969 1.1549085175938314 0.8810151605143554 1.0973249225915411 1.0 14.899552254691768 -5.735413378276569 24.99995949921933 0.9986157609125274 1.191345646640246 0.45901393277608515 0.10314461321486607 216.04987407489187 207530.64964963857 0.027612132480426328 0.047805612082892135 1.839020717120801e-06 5.735413378276569 0.19272988572771854 VREEEIEVDSR ddPTM_PC-9_AZD4547_30min_R2 1 VREEEIEVDSR 11 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 0 86.463 0.014135 5192900.0 27724.0 20848.0 28565.0 37542.0 38981.0 27319.0 27319.0 31444.0 20872.0 29211.0 False True 36539.655304976535 27586.708295139662 28186.20943596055 28887.27191811809 33569.16101103842 25610.73861133114 29750.33807608442 26585.0523112375 21975.251308967472 28188.33178113641 1.2962688103958255 0.9786570028099586 0.9999247083796112 1.0247953707373847 1.1908885304629078 0.9085581513010929 1.0554132222891353 0.9431225841122027 0.7795867978137421 1.0 14.782810479582764 -7.475105436565928 1.1748708363887983 0.8933660660995945 1.0752545951630685 0.2907972836249607 0.11466517177270412 0.6601998444275445 1.7137050086542978 0.08479609829103195 0.04057397108450104 3.348841272363489e-08 7.475105436565928 0.18188852906347408 VREEEIEVDSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VREEEIEVDSR 11 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 0 ; 131.17 0.00022309 4802200.0 63636.0 65586.0 76598.0 89137.0 90790.0 77342.0 68925.0 78520.0 70594.0 53899.0 False True 74408.31793170882 72096.94463722612 78424.38681953259 84142.94287605301 73000.3512414682 73286.0493671904 62395.925026213205 76458.933198817 71626.30369927293 63670.462035750745 1.1686473688525898 1.1323452403524876 1.2317232247427006 1.3215381227924345 1.1465340270419078 1.1510211646656583 0.9799822874094758 1.2008540656715445 1.1249534149611637 1.0 15.95833661297597 -6.741953620506734 2.717745076912396 1.092709735413266 1.209435753289823 0.3618731797999246 0.07629383742224613 0.3368955563390866 5.101030080342496 0.02911043344254223 0.027319608669766328 1.8115335409019693e-07 6.741953620506734 0.11672601787655701 VREEEIEVDSR ddPTM_PC-9_Lapatinib_30min_R1 2 VREEEIEVDSR 11 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 0 ; 117.2 0.0015369000000000001 15045300.0 57767.0 44259.0 60070.0 49692.0 60752.0 48738.0 41851.0 52378.0 52486.0 41720.0 False True 56943.23198682963 44156.52100476483 55131.2764769056 53346.515447652586 57178.68680302752 46653.589353827105 44017.84000148431 54811.67309528985 46574.47397791763 48931.24641159433 1.1637396584554782 0.9024197060776665 1.1267090156085247 1.0902341419819637 1.1685516106019107 0.9534518896451505 0.899585504755387 1.1201773327871358 0.9518350214533211 1.0 15.57846841214512 -6.783356484684766 24.99876410488976 0.9871819962524563 1.0819069970317496 0.26361272749791753 0.087411948695445 381.31305920668547 434924.83815707295 0.030771328849430197 0.027159283490646485 1.646810075062766e-07 6.783356484684766 0.09472500077929336 VREEYPDR ddPTM_PC-9_AZD4547_30min_R2 2 VREEYPDR 8 1 A0A0B4J269;Q13509;Q13509-2;G3V2A3 A0A0B4J269 TUBB3 Tubulin beta-3 chain 0 ; 128.12 0.004759 5482700.0 23979.0 22955.8 31031.0 47938.0 40234.0 29269.0 23408.0 35409.0 29617.0 30019.0 False True 31603.823205815628 30375.81342486412 30619.5086647048 36886.63473471695 34648.203589392804 27438.80480306934 25491.266652695347 29937.352667873307 31182.494155696128 28968.043947072474 1.0909892039503595 1.048597326086766 1.0570098802891117 1.2733560747875328 1.1960836448846375 0.947209444075782 0.8799788725559258 1.033461310766162 1.076444588825869 1.0 14.822174650173203 -6.768140708501867 24.999990506481183 0.9827951622531018 1.1320595405978546 0.46169655182640923 0.07862557206254756 162.63440173063944 606720.4745719178 0.030667337569902572 0.027661899623803093 1.7055297192772687e-07 6.768140708501867 0.1492643783447528 VREEYPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VREEYPDR 8 1 A0A0B4J269;Q13509;Q13509-2;G3V2A3 A0A0B4J269 TUBB3 Tubulin beta-3 chain 0 ; 105.1 0.0049873 17255900.0 85611.0 85859.0 77816.0 104341.0 115586.0 97756.0 95130.0 89353.0 84016.0 82583.0 False True 100103.25140567512 94382.51409763691 79671.42855882338 98495.1120480864 92937.75304104343 92629.5032703973 86118.59771844253 87007.57842732927 85244.5750573439 97554.64417333147 1.0261249195662625 0.9674835564972342 0.8166851433260947 1.0096404213528158 0.9526737945547223 0.949514029345611 0.8827729161251432 0.8918855597765026 0.8738136024142993 1.0 16.573922934765598 -7.241971618536729 21.663108514629716 0.9031084980221892 0.9505840490826997 0.08971148210067559 0.061805942929242484 329.24314768455184 366370.77801342524 0.023636394182430694 0.0182586614289511 5.72833464850179e-08 7.241971618536729 0.04747555106051049 VREEYPDR ddPTM_PC-9_Lapatinib_30min_R1 2 VREEYPDR 8 1 A0A0B4J269;Q13509;Q13509-2;G3V2A3 A0A0B4J269 TUBB3 Tubulin beta-3 chain 0 ; 112.11 0.0048418 7961500.0 34042.0 34500.0 33045.0 25297.0 35756.0 31729.0 28873.0 28296.0 31349.0 22416.0 False True 33556.55483746177 34420.11736967366 30328.167657388818 27157.42576831817 33652.90237900071 30372.024633911522 30367.902663326007 29610.735459626598 27818.14550039515 26290.57573255749 1.2763720041287 1.3092188516453362 1.153575637365419 1.0329718924598217 1.2800367219545494 1.155243800777618 1.155087015676088 1.1262870680674186 1.0581033212576612 1.0 14.68225811516881 -1.5228787470117888 0.09122105488391687 0.8929394758203905 1.9541075130501988 0.5294622277310861 0.06971137628623045 134.11777166814014 0.8815983566588713 1.3196782782193022 17.80202093303341 0.029999999880395586 1.5228787470117888 1.0611680372298085 VREYELR ddPTM_PC-9_AZD4547_30min_R2 2 VREYELR 7 1 Q5VVC8;P62913-2;P62913 Q5VVC8 RPL11 60S ribosomal protein L11 0 ; 87.696 0.023032 10704500.0 51329.0 50204.0 67077.0 97093.0 83242.0 79930.0 62624.0 82771.0 61176.0 73599.0 False True 67650.5542904754 66431.4612072712 66187.51515266683 74709.70892189647 71685.28516151098 74931.96446442748 68197.41468123689 69980.64383836139 64409.638466720666 71022.32141179196 0.9525252476363475 0.9353603189354703 0.9319255388585146 1.0519187128328966 1.0093345829387232 1.0550480887546207 0.9602250859391643 0.9853330959517521 0.9068928920707825 1.0 16.11598489612554 -5.719111238735338 24.997681451829465 0.9965083448063924 0.9394792614216403 0.28347217104389144 0.0404851064717264 193.13406823885944 114057.50677592462 0.011471630410232133 0.019869240099304655 1.909364137786984e-06 5.719111238735338 -0.0570290833847521 VREYELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VREYELR 7 1 Q5VVC8;P62913-2;P62913 Q5VVC8 RPL11 60S ribosomal protein L11 0 ;; 101.33 0.014562 34315500.0 87512.0 69797.0 100952.0 114180.0 118101.0 102472.0 114068.0 110817.0 108962.0 82224.0 False True 102326.05315921325 76725.98488769685 103359.07854259205 107782.8647765545 94959.95684512208 97098.18792835386 103262.65325919593 107908.171170317 110555.36311414841 97130.56031517393 1.053489785575011 0.7899263078348634 1.0641252166898607 1.1096699579083602 0.977652723684404 0.9996667126523822 1.0631324778125884 1.1109600399727064 1.1382139952185288 1.0 16.56763766364395 -5.317236989658572 24.99354537829513 1.0589766828484533 0.9217077489909417 0.3311911856414983 0.07741884741442122 276.9568835499483 124057.29694750602 0.01985503706917472 0.041331586917376595 4.816848758265327e-06 5.317236989658572 -0.1372689338575116 VREYELR ddPTM_PC-9_Lapatinib_30min_R1 2 VREYELR 7 1 Q5VVC8;P62913-2;P62913 Q5VVC8 RPL11 60S ribosomal protein L11 0 ; 87.696 0.023032 36966000.0 232770.0 172011.0 214316.0 171875.0 165918.0 190301.0 143685.0 139519.0 197404.0 139959.0 False True 229450.65711521026 171612.71909782442 196695.76576368383 184515.2608581918 156159.0294473386 182162.26984329772 151124.3062438954 146001.5620791506 175170.2827637247 164150.72666635545 1.3978046992236604 1.0454581748312077 1.1982631436257836 1.1240599697936657 0.9513148836967358 1.109725637788687 0.9206435409272546 0.8894359778004887 1.0671307177321674 1.0 17.32466161091869 -1.522878745285568 0.4095815281230364 0.9709619440781482 7.266304269205681 0.6066901946850175 0.08933533776314409 51.85986211137112 0.6770703511593743 0.06177930931724132 265.41673588734454 0.029999999999638687 1.522878745285568 6.295342325127533 VRGEVAPDAK ddPTM_PC-9_AZD4547_30min_R2 3 VRGEVAPDAK 10 1 P09382;F8WEI7 P09382 LGALS1 Galectin-1 0 ;; 110.08 0.0023224 30948700.0 175710.0 160099.0 214760.0 291239.0 258971.0 227742.0 203302.0 246960.0 200442.0 207351.0 False True 231582.12500495667 211847.8708434175 211912.14207830888 224098.3481476956 223017.34681484906 213501.25673786673 221395.48415183986 208798.0065762378 211036.95490954677 200091.70460273267 1.1573799396868847 1.0587538911921703 1.0590751000849576 1.119978204956704 1.1145756754765699 1.0670170318242715 1.106470078764156 1.0435115588164479 1.054701169788848 1.0 17.61030183170258 -8.364764597721019 0.8243731537697124 1.0011954878316307 1.097319607153224 0.5063811921254702 0.03052541515629336 0.5163288219895549 0.7791382525453078 0.029001940526537855 0.010814739169447597 4.317530381451872e-09 8.364764597721019 0.09612411932159337 VRGEVAPDAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VRGEVAPDAK 10 1 P09382;F8WEI7 P09382 LGALS1 Galectin-1 0 ;;; 95.477 0.007649899999999999 34252600.0 525080.0 507412.0 549480.0 637200.0 642310.0 585180.0 645780.0 542890.0 540843.0 483165.0 False True 613965.673197272 557784.5099909155 562581.6871145045 601499.7498302743 516453.96636091615 554492.1306494846 584607.0433576781 528639.7127395011 548751.805700569 570758.9897679639 1.0757003992996648 0.9772680237900011 0.9856729323583957 1.053859440873297 0.9048547208531488 0.9714996006894391 1.0242625238287426 0.9262047943465842 0.9614422471447331 1.0 19.12252215230601 -2.0096436791772874 1.2442485248732724 0.9748706332984239 132.28014975520512 0.32304447914319756 0.04139921577813912 2178.287006173604 3.4730370378626176 0.01251177662415812 816345.314759506 0.009780393330482988 2.0096436791772874 131.3052791219067 VRGEVAPDAK ddPTM_PC-9_Lapatinib_30min_R1 4 VRGEVAPDAK 10 1 P09382;F8WEI7 P09382 LGALS1 Galectin-1 0 ;;; 99.75200000000001 0.0055122 61401000.0 476158.0 417310.0 449105.0 409693.0 423669.0 422210.0 422994.0 405388.0 412860.0 401029.0 False True 469367.8996033172 416343.74433445005 412181.3204954326 439823.18991578254 398749.6223853025 404153.062519581 444894.5595944624 424223.80642165267 366359.3591914621 470346.32831244543 0.9979197696458294 0.8851854883788481 0.8763357885120461 0.9351049714660752 0.8477787502157728 0.8592669660452987 0.9458871746500044 0.9019392326155162 0.7789140408641481 1.0 18.843363916636562 -4.760117783623682 24.895110506786036 0.8892984351869156 0.9979199070587434 0.23353622404461316 0.05719316899249736 44.92449696387243 845911.0551807849 0.013469648954716558 0.08150734872747091 1.737329589224189e-05 4.760117783623682 0.1086214718718278 VRGGAPDPSPGATATPGAPAQPS(ph)SPDAR ddPTM_PC-9_AZD4547_30min_R2 2 VRGGAPDPSPGATATPGAPAQPSSPDAR 28 1 O95365 O95365 ZBTB7A Zinc finger and BTB domain-containing protein 7A 1 VRGGAPDPSPGATATPGAPAQPS(0.5)S(0.5)PDAR;VRGGAPDPSPGATATPGAPAQPS(0.5)S(0.5)PDAR 167.97 5.1380999999999995e-14 58742000.0 70395.0 43007.0 75111.0 159944.0 124171.0 103208.0 71195.0 85071.0 54719.0 101180.0 True False 92779.14569303943 56908.17170227705 74114.97906334444 123071.38191016666 106931.99999747686 96754.38744457197 77531.21707700993 71925.23168710354 57611.33462894749 97637.71899679529 0.9502387668036845 0.5828502784271816 0.7590814269818928 1.260490138183238 1.0951915007455943 0.9909529681633354 0.7940703436502311 0.7366541581073224 0.5900520333831072 1.0 16.5751509709564 -7.403298640245835 4.710267767798886 0.7505748343125759 0.9364143154297274 0.13524906448218055 0.1945026525147547 0.4830094882247329 16.488911379328634 0.09340467119218573 0.061199947354498824 3.950948418095578e-08 7.403298640245835 0.18583948111715154 VRGGAPDPSPGATATPGAPAQPS(ph)SPDAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VRGGAPDPSPGATATPGAPAQPSSPDAR 28 1 O95365 O95365 ZBTB7A Zinc finger and BTB domain-containing protein 7A 1 VRGGAPDPSPGATATPGAPAQPS(0.5)S(0.5)PDAR;VRGGAPDPSPGATATPGAPAQPS(0.5)S(0.5)PDAR 167.95 5.1573000000000004e-14 25867000.0 58870.0 34555.0 54532.0 78792.0 81151.0 94172.0 71775.0 72400.0 77189.0 65080.0 True False 68835.52826449966 37985.39203396078 55832.24969376166 74377.53968711062 65250.044097327765 89233.45453966873 64975.952394 70499.57671414106 78317.74309775901 76878.48882700352 0.895380870706205 0.4940964971285757 0.7262402077048973 0.9674688046285524 0.848742542847808 1.1607077077239003 0.8451772841192638 0.9170260470751883 1.0187211571496182 1.0 16.23029235739869 -5.713814293297098 4.69111861480847 0.9609739450845153 0.6765318990717821 0.477655570750092 0.12432511739103007 0.15714432949933843 7.400764775355806 0.03292217482730929 0.05697556135317004 1.932794613919571e-06 5.713814293297098 -0.28444204601273315 VRGGAPDPSPGATATPGAPAQPS(ph)SPDAR ddPTM_PC-9_Lapatinib_30min_R1 2 VRGGAPDPSPGATATPGAPAQPSSPDAR 28 1 O95365 O95365 ZBTB7A Zinc finger and BTB domain-containing protein 7A 1 VRGGAPDPSPGATATPGAPAQPS(0.5)S(0.5)PDAR;VRGGAPDPSPGATATPGAPAQPS(0.5)S(0.5)PDAR 162.02 6.4981e-12 65261000.0 193218.0 109832.0 152673.0 127452.0 98043.0 117699.0 67847.0 76770.0 117492.0 76218.0 True False 190462.67588815858 109577.6907520577 140120.81527482302 136825.245247408 92276.30349995433 112665.2881397696 71359.78568207946 80337.01446266369 104258.81371439037 89392.17974589861 2.1306413651569693 1.2258084662834863 1.5674840424869703 1.530617618189198 1.0322637143680127 1.2603483711889103 0.798277722782048 0.8987029367784224 1.1663079926090947 1.0 16.44786100586525 -1.52287874528034 0.3253465410263551 0.9346262489964513 11.117269010414132 0.6725928333679534 0.21401318598208288 35.008923828342674 0.49909411582790353 0.19860418005503389 213.3128220376179 0.02999999999999983 1.52287874528034 10.18264276141768 VRGGAPDPSPGATATPGAPAQPS(ph)SPDARR ddPTM_PC-9_Lapatinib_30min_R1 1 VRGGAPDPSPGATATPGAPAQPSSPDARR 29 2 O95365 O95365 ZBTB7A Zinc finger and BTB domain-containing protein 7A 1 VRGGAPDPSPGATATPGAPAQPS(0.5)S(0.5)PDARR 135.17 2.4078e-12 0.0 19256.0 3967.0 6114.5 4846.8 5420.0 5359.4 3102.1 3277.5 6716.1 3695.4 True False 18981.405908882076 3957.8146552317544 5611.78941265256 5203.249840450824 5101.206256129992 5130.190955371601 3262.711559308126 3429.7846151020008 5959.662094331678 4334.144966189018 4.379504159864843 0.9131708067235765 1.294785812756735 1.2005251049611299 1.1769809953116184 1.1836685194871412 0.7527924388225999 0.7913405393354401 1.3750490906103598 1.0 12.081531693401546 -4.759714002971173 24.999999875849394 1.077032119799602 4.379508267786374 0.9615742342561316 0.19808558615701402 7.92518406772723 114798.91843176927 0.05118817724070817 0.31889631999415174 1.738945603959789e-05 4.759714002971173 3.3024761479867717 VRMADNEVMDAFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VRMADNEVMDAFR 13 1 O75528 O75528 TADA3 Transcriptional adapter 3 0 91.09299999999999 0.03196 8018200.0 45130.0 40009.0 38382.0 58968.0 52950.0 34447.0 36468.0 40468.0 37131.0 42191.0 False True 52769.61764186967 43980.8291097305 39297.17244454559 55664.21413683541 42574.82760475544 32640.538679522233 33013.48703454401 39405.75787939024 37673.9706300494 49839.894316227794 1.0587826953856112 0.8824422626315723 0.7884682137407842 1.11686059732898 0.8542318997432773 0.6549078630147601 0.6623907913021971 0.7906468988350119 0.7558998899759467 1.0 15.605013388729668 -6.524058468031674 24.908426421790587 0.752984071047776 0.9488540187690735 0.3371669473704071 0.1227658734588165 41.37822079031227 873618.3080626085 0.03944081112694882 0.03974932065828049 2.991861822262867e-07 6.524058468031674 0.1958699477212975 VRMAS(ph)PRGQSIKS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 VRMASPRGQSIKSR 14 3 H0Y3Z0;A0A0A0MSC0;F8WEA4;A0A0A0MSD9;A0A0A0MRC8;Q9NR82-2;Q9NR82;Q9NR82-7;Q9NR82-3;Q9NR82-6 H0Y3Z0 KCNQ5 Potassium voltage-gated channel subfamily KQT member 5 2 VRMAS(1)PRGQS(0.002)IKS(0.998)R 86.49700000000001 0.014703 0.0 26301.0 21117.0 27192.0 16986.0 22492.0 21523.0 12302.0 18206.0 25486.0 16932.0 True False 25925.942916987296 21068.10488392462 24956.37872415542 18235.20710363492 21169.064780973385 20602.51146256351 12938.937365851705 19051.91722427064 22615.4983005222 19858.67363952818 1.305522382188827 1.0609019145160379 1.2566991722186516 0.9182489946024496 1.065985833960074 1.03745657119591 0.6515509344036493 0.9593751108507211 1.138822194827082 1.0 14.277481648056414 -5.764781520466377 24.99999863748679 0.9595286237079175 1.1930272506013786 0.3979625824413172 0.1348742869182091 90.938252757355 680247.6176400624 0.038813303132268245 0.06034770152326418 1.7187728288264692e-06 5.764781520466377 0.23349862689346113 VRPAS(ph)TGGLSLLPPPPGGK ddPTM_PC-9_AZD4547_30min_R2 2 VRPASTGGLSLLPPPPGGK 19 1 D6RB24;Q9NVZ3-4;Q9NVZ3;Q9NVZ3-2 D6RB24 NECAP2 Adaptin ear-binding coat-associated protein 2 1 VRPAS(0.508)T(0.357)GGLS(0.135)LLPPPPGGK;VRPAS(0.379)T(0.379)GGLS(0.242)LLPPPPGGK 132.86 2.0288e-05 56402000.0 124286.0 115193.0 154312.0 218479.0 202163.0 176624.0 125801.0 141530.0 121736.0 160657.0 True False 163806.36269060418 152426.8845281095 152265.72205433052 168112.04201690148 174096.1570373919 165579.67335875198 136997.04529117057 119659.79053585549 128170.71643103039 155032.44733018515 1.0565940582859568 0.9831934356520454 0.982153895371579 1.0843668207008283 1.122965934135099 1.0680323778034901 0.8836669203795569 0.771837074086861 0.8267347812555319 1.0 17.242210668667404 -7.332624037251333 4.70353166850017 0.8468462202509107 1.0484204247814992 0.6220189351760087 0.06774632435855264 0.1407792245988881 5.970773789927716 0.03007009865247141 0.020041510509957616 4.649175738028137e-08 7.332624037251333 0.2015742045305885 VRPAS(ph)TGGLSLLPPPPGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VRPASTGGLSLLPPPPGGK 19 1 D6RB24;Q9NVZ3-4;Q9NVZ3;Q9NVZ3-2 D6RB24 NECAP2 Adaptin ear-binding coat-associated protein 2 1 VRPAS(0.62)T(0.282)GGLS(0.098)LLPPPPGGK 77.1 0.0016602000000000001 17638000.0 50736.0 50351.0 60198.0 61342.0 85434.0 83714.0 92944.0 79558.0 75306.0 76334.0 True False 59324.60271832262 55349.514521833575 61633.34862218634 57905.20661344727 68693.82099310047 79323.89046992557 84139.67146371232 77469.68679866893 76407.2077850448 90172.74994038836 0.657899451414547 0.6138164196880341 0.6835030390326465 0.6421585972672166 0.7618024407430489 0.8796880490210759 0.9330942165935452 0.8591252551339823 0.8473425490024012 1.0 16.46040389877834 -6.565839572825557 2.192978354466685 0.9003939026480992 0.6475070662981294 0.8867847936022194 0.042974657739531595 0.09769798595665986 0.9511738670090228 0.015514188818076183 0.016245143608550443 2.7174428993120723e-07 6.565839572825557 -0.2528868363499698 VRPAS(ph)TGGLSLLPPPPGGK ddPTM_PC-9_Lapatinib_30min_R1 2 VRPASTGGLSLLPPPPGGK 19 1 D6RB24;Q9NVZ3-4;Q9NVZ3;Q9NVZ3-2 D6RB24 NECAP2 Adaptin ear-binding coat-associated protein 2 1 VRPAS(0.434)T(0.169)GGLS(0.397)LLPPPPGGK;VRPAS(0.485)T(0.485)GGLS(0.03)LLPPPPGGK 70.15 0.0034111 36471000.0 162027.0 137877.0 154872.0 106787.0 162266.0 195818.0 170826.0 157567.0 197863.0 169810.0 True False 159716.46526788722 137557.75427763778 142139.02198320837 114640.47221098903 152721.83290723054 187443.32061405323 179670.5344219624 164888.13804661424 175577.58535024055 199161.43224239768 0.801944751398944 0.6906847009927977 0.7136874864919237 0.5756158254147373 0.766824335353012 0.9411627467406318 0.9021351794823754 0.8279119917451201 0.8815842674627212 1.0 17.603578769936213 -6.594670125139951 4.899100943415064 0.8979630949514077 0.6934471638443459 0.702631485155504 0.06625402277768973 0.12041075737879907 5.440188490012677 0.022317125904116532 0.022421326591923613 2.54290347249661e-07 6.594670125139951 -0.2045159311070618 VRPAST(ph)GGLSLLPPPPGGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VRPASTGGLSLLPPPPGGK 19 1 D6RB24;Q9NVZ3-4;Q9NVZ3;Q9NVZ3-2 D6RB24 NECAP2 Adaptin ear-binding coat-associated protein 2 1 VRPAS(0.203)T(0.763)GGLS(0.034)LLPPPPGGK 82.56 0.0013067999999999999 19906000.0 65632.0 52321.0 86482.0 88830.0 131400.0 104740.0 122510.0 100060.0 88686.0 88674.0 True False 76742.20130891187 57515.08310255717 88544.05886481154 83853.14309074562 105653.11326279266 99247.2500157679 110904.96590440879 97433.53102233357 89982.86497257184 104749.89425700213 0.7326231864313499 0.5490705600279162 0.8452901980747604 0.8005081407052624 1.0086226245114338 0.9474687370305732 1.0587596931821743 0.9301539797575549 0.8590258311077659 1.0 16.676589261989356 -5.708860022980216 1.4663269063487676 0.9658126337189353 0.641907287917796 0.7007735882091115 0.07902348944224809 0.22175201146910067 0.9503754820791178 0.025078717585421982 0.06237764947848499 1.9549694584916356e-06 5.708860022980216 -0.3239053458011393 VRS(ph)LETENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VRSLETENR 9 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 VRS(0.999)LET(0.001)ENR 67.749 0.021190999999999998 16531000.0 17903.0 20499.0 31989.0 34359.0 29495.0 30062.0 35648.0 32154.0 30865.0 23011.0 True False 20933.62429963203 22534.00524682859 32751.739078958068 32433.976623380946 23715.666481629112 28485.49579887357 32271.163370829876 31309.99156997912 31316.34223415678 27182.712145024212 0.7701080079113417 0.8289829626494218 1.204873851594432 1.1931839784911962 0.8724540198602021 1.0479269193926932 1.1871943902675328 1.1518347177034873 1.152068346494602 1.0 14.730401787198945 -5.173944467187518 5.802725690536778 1.102512883349394 0.788867930263266 0.597976506525952 0.0991392759547852 0.15873963954906262 8.289284947636988 0.026917327353884683 0.07400817518196318 6.699702723858983e-06 5.173944467187518 -0.31364495308612805 VRS(ph)LETENR ddPTM_PC-9_Lapatinib_30min_R1 2 VRSLETENR 9 1 P05783;F8VZY9 P05783 KRT18 Keratin, type I cytoskeletal 18 1 VRS(0.993)LET(0.007)ENR;VRS(0.991)LET(0.009)ENR 75.788 0.012014 36134000.0 46760.0 34560.0 43872.0 37947.0 44804.0 44942.0 35821.0 44455.0 46301.0 32475.0 True False 46093.19382526623 34479.978443360094 40265.01351081743 40737.74896748109 42168.71680805317 43019.93542491892 37675.636106500904 46520.54159095634 41086.093808854996 38088.26047978251 1.2101679951945505 0.9052652446982262 1.0571502348391666 1.0695618139112693 1.1071316010988894 1.1294801832116794 0.989166625934502 1.2213879291140044 1.0787075411507374 1.0 15.217058779960599 -5.927035449690361 3.102287189870555 1.095504099742702 1.0424825161803097 0.009563792958644068 0.09220150912424709 0.7912755907627337 15.403190000543722 0.02618184185288959 0.04066989691499044 1.1829449928007082e-06 5.927035449690361 -0.05302158356239217 VRS(ph)SPSGNTQSSPK ddPTM_PC-9_Lapatinib_30min_R1 1 VRSSPSGNTQSSPK 14 1 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 VRS(0.49)S(0.49)PS(0.02)GNTQSSPK 103.66 0.0016554000000000002 0.0 9665.6 7820.5 9607.6 5609.8 8236.0 7341.7 7814.7 4862.8 8559.5 6686.5 True False 9527.76677154605 7802.3921127400845 8817.700214408493 6022.363405744214 7751.574672599004 7027.712605338594 8219.306928379237 5088.743440524185 7595.438974469118 7842.252615798796 1.2149272968268916 0.9949172125648682 1.1243835982335721 0.767937951094781 0.9884372580631853 0.8961344335147721 1.0480798478514755 0.6488879777058617 0.9685277109242243 1.0 12.937052399570694 -2.7055261593215003 0.5806840200601261 0.8937415600788762 4.676485069065383 0.33346086187283464 0.12672988919506534 39.55986390410535 1.3707261499246908 0.05721303420284945 165.78320914005303 0.0019700345404568454 2.7055261593215003 3.782743508986507 VRSPTRS(ph)PSVKT(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 VRSPTRSPSVKTSPR 15 3 Q03164-2;Q03164;Q03164-3;E9PR05;A0A3B3ISN4 Q03164-2 KMT2A Histone-lysine N-methyltransferase 2A;MLL cleavage product N320;MLL cleavage product C180 2 VRS(0.049)PT(0.279)RS(0.666)PS(0.006)VKT(0.554)S(0.445)PR 88.385 0.012012 17381000.0 53246.0 46055.0 43535.0 33900.0 32075.0 42893.0 43509.0 36005.0 40540.0 31007.0 True False 70177.12041439828 60941.37809538837 42957.69745473631 26084.878749778996 27621.93990480125 40210.89392934683 47381.216711898545 30441.254562590835 42682.86163594968 29921.454367796272 2.34537798703823 2.036711763615945 1.4356821338527792 0.871778437944297 0.9231483057364372 1.3438816654789625 1.5835198426348482 1.0173721567275824 1.4264968912035305 1.0 14.86889268038374 -5.24603012185126 2.584281505096394 1.1803770078840172 2.294281462735422 0.7717973442662067 0.22154055346647117 0.1406518682128998 1.8007655472337325 0.06380504030244546 0.2131283762145723 5.675052429435428e-06 5.24603012185126 1.113904454851405 VRSS(ph)PSGNTQSSPK ddPTM_PC-9_Lapatinib_30min_R1 1 VRSSPSGNTQSSPK 14 1 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 VRS(0.043)S(0.954)PS(0.003)GNTQSSPK 77.192 0.0072741 1297100.0 9406.9 6766.5 6402.2 6570.9 7139.5 8040.3 6369.2 6456.6 6267.5 5317.5 True False 9272.755880985818 6750.832584982521 5875.835829206679 7054.145905879825 6719.568646797063 7696.435111854735 6698.966011265058 6756.597206977143 5561.5881502991 6236.6227898766265 1.4868232685224263 1.0824500394573433 0.9421502674082546 1.1310842652421136 1.0774370798414104 1.2340709661561857 1.0741335875145301 1.0833743573436165 0.891762791767164 1.0 12.606549287586027 -4.762847598532067 6.134318977262495 1.0644030509212232 1.5010061965897614 0.6670783385880351 0.09097750938283604 0.07923240737336155 12.153310854596079 0.023013006100296347 0.14544867662059338 1.726443624721551e-05 4.762847598532067 0.4366031456685382 VRSVNSLMVASLT(ph)Y(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 VRSVNSLMVASLTYK 15 1 P23510-2;P23510 P23510-2 TNFSF4 Tumor necrosis factor ligand superfamily member 4 2 VRSVNS(0.004)LMVAS(0.34)LT(0.853)Y(0.803)K 64.374 0.042482 0.0 12737.0 16162.0 18739.0 25642.0 22331.0 20292.0 17359.0 24814.0 15919.0 18654.0 True False 16787.10105394193 21386.050434864123 18490.508616154915 19730.633064950827 19230.72611111822 19023.138032180224 18903.917371161067 20979.56646899401 16760.445840717395 18000.929137835716 0.9325685871768435 1.1880525872363612 1.0271974560074326 1.0960897025853786 1.0683185275529818 1.0567864517724228 1.0501634235883626 1.1654713103057313 0.9310878184331619 1.0 14.135783754323986 -8.281358005431178 24.900990281899 0.965543894738207 1.0746850809848547 0.2807838005823672 0.0688050291061132 1061.6298058347568 1327168.5230429927 0.05983774547899988 0.015524999045508912 5.231689907183026e-09 8.281358005431178 0.1091411862466477 VRT(ph)INLY(ph)Y(ph)NNRT(ph)VQAIVELK ddPTM_PC-9_Lapatinib_30min_R1 1 VRTINLYYNNRTVQAIVELK 20 2 Q5T4S7-6 Q5T4S7-6 UBR4 E3 ubiquitin-protein ligase UBR4 4 VRT(1)INLY(1)Y(1)NNRT(1)VQAIVELK 51.348 0.033252 0.0 3892.5 3333.1 3799.5 3660.0 3285.8 4989.6 3807.1 3082.7 4655.4 4319.4 True False 3836.9922362029242 3325.382411735053 3487.119776494137 3929.1686094020833 3092.5357041313496 4776.206439325697 4004.213009716633 3225.933495949638 4131.0598284646885 5066.002534761279 0.7574003782814395 0.6564115175461025 0.688337550675635 0.7755954685062616 0.6104489058012437 0.9427959039800918 0.790408805017568 0.6367808689029113 0.8154476434069438 1.0 12.306632083561418 -6.7475627603659385 24.99993940912685 0.8114681161424145 0.6991625805384911 0.3059423990796061 0.10139766535304484 365.4085062037204 658314.1059368016 0.033447622589244136 0.03328379340814849 1.788287083130896e-07 6.7475627603659385 -0.11230553560392342 VRTELADK ddPTM_PC-9_AZD4547_30min_R2 2 VRTELADK 8 1 P35579 P35579 MYH9 Myosin-9 0 ; 74.92 0.035134 7820500.0 63896.0 52047.0 78418.0 89321.0 73526.0 70274.0 63063.0 78577.0 66876.0 68243.0 False True 84213.59888063696 68870.1749154419 77378.12608258896 68729.42344569354 63318.184051143166 65879.75567087678 68675.48483078113 66434.73016982932 70410.92882993999 65853.83334155273 1.2787956996195011 1.0458035837981492 1.1749980548780687 1.043666252338364 0.9614957981677642 1.000393634326336 1.0428471866564522 1.0088210024959936 1.069200155209671 1.0 16.006979801532907 -1.522878745284912 0.6553320239722742 1.0177479712115247 22.93814061352267 0.657184512096189 0.05280941267964226 142.65489341732697 0.9023447832836069 0.022141250897775938 4542.0081382987355 0.029999999999684012 1.522878745284912 21.920392642311146 VRTELADK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VRTELADK 8 1 P35579 P35579 MYH9 Myosin-9 0 81.33800000000001 0.023366 5687700.0 29589.0 19473.0 26928.0 37899.0 37409.0 26743.0 36018.0 31784.0 34243.0 29653.0 False True 34597.8332906112 21406.150747426374 27570.065645008697 35775.6419002158 30078.97499275347 25340.550001639127 32606.114292261846 30949.703677931688 34743.73909360864 35028.85416698114 0.9876952619027936 0.6111005128910045 0.7870672992494503 1.0213192167141625 0.858691376239948 0.7234193239904949 0.9308358799528472 0.883548846056902 0.9918605652353523 1.0 15.096256176292027 -8.002041652484792 1.329173386973841 1.0027301915945965 0.831437476770822 0.21644531552626312 0.11438855086239844 0.7005263877022617 2.226753210439136 0.10540082001427158 0.035834939368190113 9.953099541979185e-09 8.002041652484792 -0.1712927148237745 VRTELADK ddPTM_PC-9_Lapatinib_30min_R1 2 VRTELADK 8 1 P35579 P35579 MYH9 Myosin-9 0 ; 101.46 0.005935800000000001 15304700.0 75458.0 85606.0 89308.0 90407.0 90707.0 88979.0 89190.0 77060.0 85434.0 72443.0 False True 74381.9550826977 85407.78456661679 81965.44097884961 97055.83236891117 85371.79259682349 85173.57559017974 93807.82178997828 80640.48892136094 75811.52326009629 84964.67602577015 0.8754456388456933 1.0052152089735766 0.9647002120503483 1.142308037983617 1.004791597992204 1.0024586636962662 1.1040802622671797 0.9491060602279273 0.8922710802440103 1.0 16.37457554651015 -10.71071322896685 20.881888413686628 0.9999999999999951 0.9998173626386955 0.0 0.07878742287108792 0.0 0.0 0.07746094126437882 0.018787037805458796 1.9466450556900405e-11 10.71071322896685 -0.00018263736129964236 VRVDS(ph)TAK ddPTM_PC-9_AZD4547_30min_R2 2 VRVDSTAK 8 1 P78371;P78371-2;F5GWF6;F8VQ14 P78371 CCT2 T-complex protein 1 subunit beta 1 VRVDS(0.756)T(0.244)AK;VRVDS(0.755)T(0.245)AK 59.265 0.03511 75210000.0 221605.0 164505.0 205418.0 271530.0 229369.0 206854.0 228340.0 158838.0 257030.0 231158.0 True False 292070.7803296541 217678.02417939107 202694.0231022634 208932.95359668124 197525.0735471347 193919.38667990355 248661.81764680683 134293.23683412877 270616.0810628551 223065.22877901891 1.309351448131775 0.9758491960888951 0.908676014687451 0.936645100360586 0.8855036467508536 0.8693393754882842 1.1147493448794987 0.6020357254656094 1.2131701679554134 1.0 17.76710611945027 -4.759958762301775 3.747934549043406 0.928952528868558 1.358574087312501 0.33834859625124636 0.15269576161425538 0.2911221142068169 7.03948327573634 0.03488255461501214 0.3599152525177821 1.7379658465231685e-05 4.759958762301775 0.429621558443943 VRVDS(ph)TAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VRVDSTAK 8 1 P78371;P78371-2;F5GWF6;F8VQ14 P78371 CCT2 T-complex protein 1 subunit beta 1 VRVDS(0.984)T(0.016)AK 58.511 0.036506 12955000.0 37073.0 35439.0 37408.0 47574.0 66218.0 107450.0 102500.0 131820.0 124290.0 87687.0 True False 43348.726674873375 38957.14971180832 38299.948590629996 44908.58301698904 53243.05824989038 101815.13284508555 92790.4579642635 128359.86467483494 126107.50611642154 103583.9589700901 0.4184887998670753 0.37609249635898945 0.3697478738159556 0.43354765992248284 0.5140087208412678 0.9829237447323741 0.8957994933468104 1.239186703724067 1.2174424241965411 1.0 16.66044107875355 -6.829559734176946 1.3790743202168618 1.1397081023499407 0.37833447343656806 0.920785382378255 0.09526482678250409 0.1023536212753557 0.40548295197661105 0.04538025658941363 0.038614039593691994 1.4806085938763275e-07 6.829559734176946 -0.7613736289133726 down VRYDS(ph)SNQVK ddPTM_PC-9_AZD4547_30min_R2 3 VRYDSSNQVK 10 1 A0A087WZ12;A0A087WT34;A0A087X1H1;A0A0A0MTS6;K7EIE8;O95983-2;O95983 A0A087WZ12 MBD3 Methyl-CpG-binding domain protein 3 1 VRYDS(0.815)S(0.185)NQVK;VRYDS(0.922)S(0.078)NQVK;VRYDS(0.927)S(0.073)NQVK 142.97 0.00056558 43341000.0 67691.0 65410.0 87191.0 123888.0 98842.0 91381.0 78884.0 91094.0 72122.0 87213.0 True False 89215.32993973335 86552.50333773441 86034.79037041258 95327.53565051981 85119.49443711207 85666.9316242193 85904.52318144296 77017.51543187491 75934.2216800188 84159.69941557136 1.0600718700193763 1.0284317070852125 1.0222801527080345 1.1326981478368037 1.011404449257849 1.0179091919186332 1.0207322955997722 0.9151353434803857 0.9022634611022545 1.0 16.360841931465323 -7.654449911994316 3.994386119161713 0.9315225683110676 1.0443522863764854 0.5747789989245992 0.040684751423117546 0.15400692593911738 4.510252718068607 0.021071675909944083 0.011357486585658636 2.215899645481835e-08 7.654449911994316 0.11282971806541775 VRYDS(ph)SNQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VRYDSSNQVK 10 1 A0A087WZ12;A0A087WT34;A0A087X1H1;A0A0A0MTS6;K7EIE8;O95983-2;O95983 A0A087WZ12 MBD3 Methyl-CpG-binding domain protein 3 1 VRYDS(0.7)S(0.3)NQVK;VRYDS(0.891)S(0.109)NQVK;VRYDS(0.772)S(0.228)NQVK 121.21 0.00030274 22454900.0 44438.0 45964.0 47767.0 51915.0 64117.0 76357.0 76502.0 79304.0 68668.0 60151.0 True False 51960.47570949268 50527.00215450656 48905.94643735627 49006.37086070089 51553.73411773566 72352.70450118382 69255.17673348362 77222.35402953369 69672.13959290697 71055.90014494595 0.731261944518319 0.7110880595620804 0.6882742508024486 0.6896875665600389 0.7255376965540076 1.0182504810099167 0.9746576511199062 1.0867831365447327 0.9805257473451711 1.0 16.116666828545185 -6.748894862991268 6.03445467483223 1.0161478771564505 0.7054410296823631 0.959586447248242 0.03108305339173516 0.027663284445188664 3.578235892934329 0.010347115263093575 0.009878381511584409 1.7828103102479434e-07 6.748894862991268 -0.3107068474740874 VRYDS(ph)SNQVK ddPTM_PC-9_Lapatinib_30min_R1 1 VRYDSSNQVK 10 1 A0A087WZ12;A0A087WT34;A0A087X1H1;A0A0A0MTS6;K7EIE8;O95983-2;O95983 A0A087WZ12 MBD3 Methyl-CpG-binding domain protein 3 1 VRYDS(0.641)S(0.359)NQVK 118.76 0.0040857 10160000.0 24266.0 21620.0 22055.0 20751.0 26265.0 29918.0 26928.0 29244.0 36767.0 29963.0 True False 23919.962390160617 21569.94021832885 20241.723034761988 22277.09776330673 24720.144338976774 28638.47688226433 28322.20008028409 30602.78300047077 32625.913286325835 35142.06462681212 0.6806646861582104 0.6137926285034423 0.5759969782571707 0.6339154514646846 0.7034346046963957 0.8149343866499583 0.8059344372918624 0.8708305367215663 0.9284005829706843 1.0 15.100911332972089 -7.267698404395698 0.6185400515877584 0.9843743459466893 0.6033535324116517 0.9300808766707381 0.03585986950578148 0.20163197953612094 0.1568348441008055 0.03477852746749739 0.02511944596733043 5.398854155425108e-08 7.267698404395698 -0.3810208135350376 VRYDSS(ph)NQVK ddPTM_PC-9_Lapatinib_30min_R1 1 VRYDSSNQVK 10 1 A0A087WZ12;A0A087WT34;A0A087X1H1;A0A0A0MTS6;K7EIE8;O95983-2;O95983 A0A087WZ12 MBD3 Methyl-CpG-binding domain protein 3 1 VRYDS(0.235)S(0.765)NQVK 96.745 0.026124 9952000.0 21892.0 16975.0 22003.0 17104.0 22139.0 28616.0 22562.0 26018.0 26184.0 27435.0 True False 21579.81606549888 16935.695430440886 20193.998274036177 18361.885217271367 20836.827546948694 27392.16038715409 23730.149963286145 27226.891263378748 23234.882190256343 32177.10319516038 0.6706575148985011 0.5263275356927752 0.6275890701395852 0.5706506613072957 0.6475669180214666 0.8512935493607152 0.7374855908985398 0.8461573155993056 0.7220936592499415 1.0 14.973746830095228 -6.654956780864108 4.421760546819196 0.8157436131344112 0.5971372009354464 0.6614727740908001 0.07975521578011874 0.13229731933228422 4.519668903487594 0.025138901866532948 0.02492199740176328 2.213314958317935e-07 6.654956780864108 -0.21860641219896482 VRYPPS(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VRYPPSPAK 9 1 P30838;A8MYB8;I3L3I9 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 1 VRY(0.007)PPS(0.993)PAK 54.343 0.045058 26830000.0 164520.0 151170.0 135190.0 180470.0 190080.0 170280.0 180020.0 144040.0 129130.0 132130.0 True False 192369.98658188325 166177.15855227507 138413.44231092976 170358.8509916339 152835.18850069688 161350.21703919198 162967.20236806577 140259.10262299533 131018.28196004109 156084.12305949532 1.2324763262984582 1.0646640753392485 0.8867874553657841 1.091455348899884 0.9791847210650629 1.0337388190193397 1.0440985231146591 0.8986122346955949 0.8394081306405535 1.0 17.25196426768938 -4.860110828940462 3.272308138067112 0.9770328023952832 1.2473284190343967 0.533890943834832 0.0743187005839095 0.23049170083333573 4.088981470229627 0.01962997096174385 0.14217691129794138 1.3800320450537996e-05 4.860110828940462 0.2702956166391135 VS(ph)DFGGR ddPTM_PC-9_AZD4547_30min_R2 2 VSDFGGR 7 0 I3L4R8;P27694 I3L4R8 RPA1 Replication protein A 70 kDa DNA-binding subunit;Replication protein A 70 kDa DNA-binding subunit, N-terminally processed 1 VS(1)DFGGR;VS(1)DFGGR 108.74 0.009715000000000001 12421300.0 42639.0 48308.0 85905.0 81274.0 74785.0 57455.0 45987.0 92123.0 50469.0 68800.0 True False 56197.31505370417 63922.61628557212 84765.84357067019 62537.534970782835 64402.393633065054 53862.32976734252 50079.753911376494 77887.5071259425 53136.68830549443 66391.3329410903 0.8464555923823464 0.9628156787014851 1.2767606826915763 0.9419532972213862 0.9700421844250356 0.8112855606489345 0.7543116200997616 1.173157755321058 0.8003557987402233 1.0 16.01870729673859 -5.976700704212372 24.998096892043957 0.9171912167036007 1.0366354266759135 0.09740263472111299 0.15028091604735822 531.7114614969427 570475.5730024715 0.04284974440272454 0.0635527192545846 1.0551137817977062e-06 5.976700704212372 0.11944420997231275 VS(ph)DFGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSDFGGR 7 0 I3L4R8;P27694 I3L4R8 RPA1 Replication protein A 70 kDa DNA-binding subunit;Replication protein A 70 kDa DNA-binding subunit, N-terminally processed 1 VS(1)DFGGR 99.13600000000001 0.011939 2613100.0 14978.0 15485.0 19038.0 17942.0 20032.0 14544.0 13653.0 11224.0 11744.0 9448.7 True False 17513.47957101539 17022.248463200205 19491.93812201705 16936.767908748832 16106.87340091521 13781.287036751284 12359.689000839882 10929.381892811016 11915.733782534822 11161.674514131948 1.5690727720864226 1.525062251335864 1.746327407893685 1.5174038525585887 1.4430517016530162 1.2346970895184777 1.1073328634687485 0.9791883716886007 1.0675578980060876 1.0 13.446265861197782 -6.839484983220893 1.2647490165669155 1.014497059756071 1.6059623782829533 0.9427344981752452 0.0621598787022487 0.09577322991351087 0.3204248136933581 0.03223352692977471 0.027043589011138115 1.4471548911003184e-07 6.839484983220893 0.5914653185268823 VS(ph)DSESEGPQK ddPTM_PC-9_AZD4547_30min_R2 2 VSDSESEGPQK 11 0 Q96ST2-3;Q96ST2 Q96ST2-3 IWS1 Protein IWS1 homolog 1 VS(0.849)DS(0.149)ES(0.001)EGPQK;VS(0.828)DS(0.171)ES(0.001)EGPQK 99.844 0.0043936999999999995 7745400.0 40870.0 43375.0 47758.0 52902.0 47363.0 55166.0 50750.0 55686.0 50282.0 41484.0 True False 53865.809851189966 57395.12050564479 47124.69771547714 40706.26122775243 40787.46499489017 51716.46129919445 55266.65168422286 47081.008236979134 52939.80386726248 40031.6577867469 1.3455802939298476 1.433743284162624 1.1771857654887952 1.016851748798394 1.0188802375402373 1.2918890737599178 1.3805736444549577 1.1760943922878464 1.3224484519047077 1.0 15.28885374124532 -11.888300160676282 1.7219045336082672 6.862074037232954e-05 1.2348518499394043 0.2185627832522321 0.13598741434598022 2119612.506744664 223436.99314748766 8215705.711673056 0.042609563618520405 1.293301672855612e-12 11.888300160676282 1.234783229199032 VS(ph)DSESEGPQK ddPTM_PC-9_Lapatinib_30min_R1 2 VSDSESEGPQK 11 0 Q96ST2-3;Q96ST2 Q96ST2-3 IWS1 Protein IWS1 homolog 1 VS(0.844)DS(0.156)ES(0.001)EGPQK;VS(0.637)DS(0.362)ES(0.001)EGPQK 158.34 0.00058861 9426200.0 15663.5 32741.0 32242.0 27101.0 38241.0 37372.0 27983.0 43431.0 34422.0 34747.0 True False 15440.135617665888 32665.190226101065 29591.187217719184 29094.097946285743 35991.73956469872 35773.686678387 29431.82281812942 45448.96281266058 30545.031880270562 40752.97265253282 0.3788713954515972 0.8015412888922326 0.726111134763566 0.7139135148335621 0.8831684469147998 0.8778178461581169 0.7222006372165888 1.1152306164305268 0.7495166583479198 1.0 15.31461767753489 -4.298667376464817 0.528493143986335 0.9035674475817805 6.007203199983141e-35 0.5360419223977089 0.12762447537516852 5.657556777589239 0.8291173668575895 0.06912171286216247 3.516112002187559 5.027274780675761e-05 4.298667376464817 -0.9035674475817805 VS(ph)DSPSHIATK ddPTM_PC-9_AZD4547_30min_R2 1 VSDSPSHIATK 11 0 Q9P2D3 Q9P2D3 HEATR5B HEAT repeat-containing protein 5B 1 VS(0.802)DS(0.179)PS(0.019)HIATK 73.219 0.01433 10670000.0 98220.0 93451.0 159360.0 223270.0 179280.0 183830.0 142340.0 185820.0 145380.0 166850.0 True False 129451.91689708528 123657.2082160926 157246.78227602574 171798.5509871138 154390.0665980596 172335.08103960613 155007.98425088226 157105.7887188062 153064.49000084767 161008.6322851877 0.8040060651393687 0.7680160154212345 0.9766357247076123 1.067014535486609 0.9588931003686504 1.0703468416175126 0.9627308924426068 0.975760035278925 0.9506601467785348 1.0 17.29677851321881 -5.29419854507277 5.80366625698592 0.9979932996970192 0.7852934316338958 0.8099687363574797 0.04056845358995164 0.0649955579868536 6.791139290092507 0.010497369864605994 0.02329570490934741 5.079271819658493e-06 5.29419854507277 -0.21269986806312347 VS(ph)DSPSHIATK ddPTM_PC-9_Lapatinib_30min_R1 1 VSDSPSHIATK 11 0 Q9P2D3 Q9P2D3 HEATR5B HEAT repeat-containing protein 5B 1 VS(0.774)DS(0.198)PS(0.028)HIATK 147.26 0.00025177 7856100.0 31918.0 23825.0 39342.0 28482.0 38886.0 32550.0 28958.0 37907.0 42224.0 17483.0 True False 31462.843466955674 23769.834676303635 36107.45262451173 30576.661293166693 36598.8019328175 31157.912377756 30457.30354741781 39668.297606307104 37468.28848156832 20504.913255366828 1.5344050996519474 1.1592262976329475 1.7609171116615765 1.4911870590412641 1.7848796274833476 1.5195339765507627 1.4853661250893664 1.9345752460535073 1.8272834425067175 1.0 14.323682020004785 -5.268528481052342 24.684301645553823 1.6295274913377333 1.3468156956846664 0.121995390787078 0.26310885743526247 731.2154403820339 2546105.1843556957 0.06511958395476707 0.14032278007651103 5.3885450611092715e-06 5.268528481052342 -0.2827117956530669 VS(ph)EGGPAEIAGLQIGDK ddPTM_PC-9_AZD4547_30min_R2 4 VSEGGPAEIAGLQIGDK 17 0 O14907 O14907 TAX1BP3 Tax1-binding protein 3 1 VS(1)EGGPAEIAGLQIGDK;VS(1)EGGPAEIAGLQIGDK;VS(1)EGGPAEIAGLQIGDK;VS(1)EGGPAEIAGLQIGDK 210.39 1.0003e-17 23630000.0 62640.9 66886.2 67755.0 67444.2 68371.0 80437.1 72328.1 85372.0 71152.3 71262.5 True False 82559.40318833881 88505.85611906994 66856.52442966941 51895.98169250278 58878.86681936603 75407.35542126381 78765.1607819044 72179.71905339556 74913.26531770066 68767.62156561688 1.2005563273634823 1.2870280242951135 0.9722093466018171 0.7546572138311418 0.8562004251257233 1.0965531990852906 1.1453814889722198 1.0496177911944056 1.0893682755367613 1.0 16.069441828169552 -5.264629192356425 24.77740565463799 0.9926561845571247 1.243792188826533 0.4385655515173035 0.11233514048398281 236.1021369075132 1833980.4241631553 0.033781079427490784 0.0753902733666007 5.43714365471956e-06 5.264629192356425 0.2511360042694084 VS(ph)EGGPAEIAGLQIGDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VSEGGPAEIAGLQIGDK 17 0 O14907 O14907 TAX1BP3 Tax1-binding protein 3 1 VS(1)EGGPAEIAGLQIGDK;VS(1)EGGPAEIAGLQIGDK;VS(1)EGGPAEIAGLQIGDK 224.99 6.1916e-29 15181300.0 47142.0 51768.3 41630.0 50008.0 50301.0 39803.5 49005.0 39966.3 42287.6 34406.5 True False 55122.20950305833 56907.51469922421 42622.6170826542 47206.21388812348 40444.88013874982 37716.13438994289 44362.89163452421 38917.2269727952 42905.97614972067 40644.12608829589 1.3562158867264127 1.4001411809322089 1.048678399187627 1.161452303970616 0.9950977922587577 0.9279602742105418 1.0914957683712925 0.9575117173943131 1.0556501093543285 1.0 15.310759247824924 -5.32140608768809 1.4984477244633088 1.0130199862262554 1.4222776940643718 0.7871140727709369 0.07074302914591687 0.21482154025629585 0.8100054232187885 0.020566330923573926 0.0957850848490381 4.7708296790651494e-06 5.32140608768809 0.4092577078381163 VS(ph)EGGPAEIAGLQIGDK ddPTM_PC-9_Lapatinib_30min_R1 4 VSEGGPAEIAGLQIGDK 17 0 O14907 O14907 TAX1BP3 Tax1-binding protein 3 1 VS(1)EGGPAEIAGLQIGDK;VS(1)EGGPAEIAGLQIGDK;VS(1)EGGPAEIAGLQIGDK;VS(1)EGGPAEIAGLQIGDK 218.25 1.6022e-22 19276600.0 45568.7 60923.0 69693.0 57628.0 74999.0 69171.0 63958.0 63704.0 68490.0 52357.3 True False 44918.88198172386 60781.93653659796 63963.11056275975 61866.155361372505 70587.70627370715 66212.71757547659 67269.43229110246 66663.92040288581 60775.93496832642 61407.18954328305 0.7314922294247427 0.9898179185314387 1.0416225044410337 1.007474138150647 1.149502310701798 1.0782567655014785 1.0954650879061547 1.0856044853819198 0.9897201845638663 1.0 15.906119955523119 -4.269896880403226 1.3316186688449279 1.0667547904616366 5.905035597862926e-22 0.8077744967190178 0.04725271606337942 1.7934649759377326 1.1036847791707525 0.013587627078067715 3.621216415001794 5.3715932522384435e-05 4.269896880403226 -1.0667547904616366 VS(ph)GAQEMVSSAK ddPTM_PC-9_AZD4547_30min_R2 1 VSGAQEMVSSAK 12 0 O60664-3;O60664;K7ERZ3;O60664-4;K7EL96;K7ER39 O60664-3 PLIN3 Perilipin-3 1 VS(0.996)GAQEMVS(0.003)S(0.001)AK 76.358 0.016505000000000002 14249000.0 41672.0 81772.0 62160.0 73094.0 54643.0 79263.0 74689.0 92681.0 65489.0 54203.0 True False 54922.82916855368 108203.19986138538 61335.717785377514 56243.30759104262 47056.76265683727 74306.67207986901 81336.17630823485 78359.28104750659 68950.61484155677 52305.36946810916 1.050041892965509 2.0686824500371306 1.1726466787080856 1.0752874544808337 0.8996545313675303 1.4206318172587262 1.5550253661400082 1.498111605832029 1.3182320580604312 1.0 15.674671435149515 -11.548776332983707 2.1810440633497055 0.6024957951981991 1.3489700556076132 0.09472381330105972 0.31400680507574336 8558329.720636245 2841539.8277097554 17016452.545447115 0.08218170283778492 2.826335197651445e-12 11.548776332983707 0.7464742604094141 VS(ph)GAQEMVSSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSGAQEMVSSAK 12 0 O60664-3;O60664;K7ERZ3;O60664-4;K7EL96;K7ER39 O60664-3 PLIN3 Perilipin-3 1 VS(1)GAQEMVSSAK;VS(1)GAQEMVSSAK 105.46 0.0015747 25612000.0 125171.0 179291.0 97935.0 81383.0 106365.0 67440.0 80032.0 59303.0 45325.0 61947.0 True False 146359.9780600594 197089.82558705987 100270.14182055565 76823.37435724582 85523.54179754146 63903.32767866516 72450.78957849681 57746.35908672233 45987.792378524384 73177.50072781782 2.0000680073024393 2.693311791559148 1.3702318448058008 1.0498223305410326 1.1687136202648472 0.8732646926047973 0.9900691996570914 0.7891272387329639 0.6284416920656393 1.0 16.159112522895814 -5.449978987445896 3.381790343568458 0.9364280532655509 2.342205645654471 0.8697641047814632 0.21584309116978767 0.07674797123754673 1.684677864822052 0.05936552667135065 0.13304122887508668 3.5483055665386944e-06 5.449978987445896 1.4057775923889202 up VS(ph)GAQEMVSSAK ddPTM_PC-9_Lapatinib_30min_R1 2 VSGAQEMVSSAK 12 0 O60664-3;O60664;K7ERZ3;O60664-4;K7EL96;K7ER39 O60664-3 PLIN3 Perilipin-3 1 VS(0.858)GAQEMVS(0.115)S(0.027)AK;VS(0.984)GAQEMVS(0.012)S(0.004)AK 78.902 0.014062 26424000.0 54033.0 130320.0 109839.0 79115.0 107617.0 105200.0 147893.0 143199.0 78121.0 121505.0 True False 53262.47951156135 130018.25204683689 100808.46141080129 84933.38101990319 101287.17964316251 100700.84123317752 155550.17589399347 149852.5483136509 69322.19032940025 142506.9773547647 0.3737534856203343 0.9123641133946888 0.7073931626508586 0.595994544242317 0.7107524243603359 0.7066379703113576 1.091526736313818 1.0515453425175088 0.48644769271069294 1.0 17.12067303195058 -7.100557092746011 8.237556585081412 0.9114056173551163 0.6766214565670756 0.2583148229083523 0.1991142891676687 0.45956339423365705 34.01626768165135 0.07445726615914722 0.05767897819365559 7.933099606757685e-08 7.100557092746011 -0.23478416078804065 VS(ph)GGTPIKIEDPNQFVPLNTNPNEVLEK ddPTM_PC-9_AZD4547_30min_R2 1 VSGGTPIKIEDPNQFVPLNTNPNEVLEK 28 1 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 VS(0.566)GGT(0.434)PIKIEDPNQFVPLNTNPNEVLEK 69.094 8.8025e-05 8356300.0 37613.0 39998.0 44939.0 39959.0 44261.0 46306.0 40576.0 53603.0 33778.0 42932.0 True False 49573.15160099853 52926.57129647912 44343.07949737905 30747.069910395832 38116.12415047261 43410.47849980964 44187.18539387245 45319.888024400956 35563.43612084627 41428.96374748378 1.1965819831544637 1.277525829974293 1.0703400588935141 0.7421636248930624 0.9200356635226635 1.0478292135039513 1.0665771334084164 1.0939179724753192 0.8584196394003759 1.0 15.338352114540402 -5.460611744596482 5.268872022230771 0.9669066659453045 1.2285977345738326 0.5385278582624451 0.10112436308608785 0.17369240996023194 9.676694802989763 0.028977263615195026 0.06072207064791998 3.462487828346208e-06 5.460611744596482 0.2616910686285281 VS(ph)GRTSPPLLDR ddPTM_PC-9_AZD4547_30min_R2 1 VSGRTSPPLLDR 12 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 VS(0.96)GRT(0.039)S(0.002)PPLLDR 80.737 0.0065902 287650000.0 35012.0 19582.0 46158.0 121250.0 104220.0 48165.0 31345.0 54460.0 43268.0 59128.0 True False 46145.08770515941 25911.49855311901 45545.91476089857 93297.68579382604 89750.85196814915 45153.23493593339 34134.644276688996 46044.45836630181 45555.05814662729 57057.94671716254 0.8087407689922947 0.4541260252767746 0.7982396384971694 1.6351392078005307 1.5729772473770576 0.7913575151899339 0.5982452268374668 0.8069771349211913 0.7983998858641845 1.0 15.800140210691543 -11.075179977857118 4.028493711655701 1.001179141169429 0.9249902925975645 0.004197151381205022 0.3647003848750587 0.004438653288067211 0.0004932805596552151 0.4058137366211723 0.09691207332691487 8.41046527680874e-12 11.075179977857118 -0.07618884857186459 VS(ph)GRTSPPLLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSGRTSPPLLDR 12 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 VS(0.583)GRT(0.397)S(0.02)PPLLDR 73.95100000000001 0.010117000000000001 150580000.0 62327.0 23081.0 24676.0 83465.0 79197.0 119790.0 64334.0 131610.0 95389.0 69698.0 True False 72877.73008563722 25372.32914298506 25264.36942425114 78788.72664718084 63678.91637042136 113508.00152175715 58239.81778217486 128155.3769523217 96783.88366674165 82333.69567093554 0.885150720998956 0.3081645848182386 0.30685333894430866 0.9569438855517559 0.7734247303185314 1.378633627420497 0.7073630948736094 1.5565361898064487 1.1755075838397855 1.0 16.329195364612794 -6.227958108280815 1.4715887364327143 1.1670047262228689 0.4966652418276545 0.46322041146214166 0.28417885789960906 0.33589897186535306 1.4560832349864563 0.1030775402063174 0.1463870203716412 5.916186985180684e-07 6.227958108280815 -0.6703394843952144 VS(ph)GRTSPPLLDR ddPTM_PC-9_Lapatinib_30min_R1 1 VSGRTSPPLLDR 12 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 VS(0.749)GRT(0.215)S(0.036)PPLLDR 92.15100000000001 0.0028389 212570000.0 1477300.0 354450.0 648760.0 518100.0 430110.0 395100.0 170250.0 255980.0 543740.0 279730.0 True False 1456233.43109636 353629.29280234297 595421.457086021 556202.8023309353 404811.77542879526 378202.49402308406 179064.71196035208 267873.7653009337 482498.27536396234 328080.9577832046 4.438640514024093 1.0778720447287302 1.814861371745551 1.695321807425572 1.2338776933719335 1.15277185417448 0.5457942855637411 0.8164867815276992 1.4706683332800938 1.0 18.32369233495276 -4.760029915337412 24.998761135950748 1.208814707827746 4.438644443415281 0.8763967114886413 0.3647719405147449 12.879882930934777 228360.77473181195 0.10149032125987037 0.6185617143622738 1.7376811286153462e-05 4.760029915337412 3.2298297355875354 VS(ph)HSPPPK ddPTM_PC-9_AZD4547_30min_R2 1 VSHSPPPK 8 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 VS(0.961)HS(0.039)PPPK 92.051 0.0082649 8346100.0 27905.0 24897.0 33360.0 38526.0 42824.0 31486.0 25680.0 35128.0 28508.0 30980.0 True False 36778.20953994267 32944.468362629115 32917.62460296323 29644.425920766524 36878.62679604706 29517.175442599353 27965.47025124815 29699.774761135708 30014.87467976451 29895.399629578107 1.2302297341947823 1.1019912351341943 1.1010933123768976 0.9916049388226517 1.2335886876574762 0.9873484150850907 0.9354439344433279 0.9934563554638404 1.0039964359622808 1.0 14.867635875938696 -6.874790433081241 10.260388107514151 0.979723874243189 1.1204723068697489 0.542889884566627 0.06732290818642288 0.26607311614568374 22.891075248625484 0.023544113519187185 0.0207680581979513 1.3341650724275106e-07 6.874790433081241 0.1407484326265599 VS(ph)HSPPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSHSPPPK 8 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 VS(0.996)HS(0.004)PPPK 98.04799999999999 0.0056258 20815000.0 64857.0 75297.0 72588.0 81975.0 87910.0 66476.0 78239.0 71511.0 70823.0 58840.0 True False 75836.0091158596 82771.98853946317 74318.7732115231 77382.20651653598 70684.66656721542 62989.88153569013 70827.63551869272 69633.91202216753 71858.65239104765 69507.2262228163 1.0910521572642735 1.1908400469632408 1.0692236944297364 1.1132972889534565 1.0169398263804206 0.9062350054621112 1.0189967197316097 1.0018226277501725 1.0338299525964896 1.0 16.08487535298099 -6.299985136009513 3.826914693415394 0.9910946255780277 1.1195018479180787 0.65213446119557 0.04308728362681589 0.14154710027918502 4.474171710132037 0.013783756801878856 0.016411446721386752 5.012043873560642e-07 6.299985136009513 0.12840722234005097 VS(ph)KMAT(ph)PY(ph)MNHYMKHQKK ddPTM_PC-9_Lapatinib_30min_R1 1 VSKMATPYMNHYMKHQKK 18 3 Q8ND82 Q8ND82 ZNF280C Zinc finger protein 280C 3 VS(1)KMAT(1)PY(0.988)MNHY(0.012)MKHQKK 42.647 0.045585 32378000.0 65026.0 50380.0 50553.0 51220.0 52965.0 57500.0 50953.0 50271.0 51837.0 37636.0 True False 64098.717315692025 50263.34820533798 46396.72748022323 54986.8896649111 49849.702833196476 55040.85903904672 53591.09702505626 52606.77418330819 45998.57119219062 44141.332453182295 1.4521246585312568 1.1386912313679902 1.051094856038455 1.245700721047149 1.1293203005611274 1.2469233704583977 1.2140797308712121 1.1917803849511026 1.0420748227520809 1.0 15.429842559112249 -14.522878743548583 0.07225788325469008 0.35395842610895195 1.4084056372876508 0.3372525599058098 0.10157714773788241 411.28732208511934 2.1240181884103673 43.59575054156507 5.05999073638141 3.000000011962536e-15 14.522878743548583 1.0544472111786989 VS(ph)KSPSPASTSTVPNMTDAPTAPK ddPTM_PC-9_AZD4547_30min_R2 2 VSKSPSPASTSTVPNMTDAPTAPK 24 1 Q659A1 Q659A1 ICE2 Little elongation complex subunit 2 1 VS(0.333)KS(0.333)PS(0.333)PAS(0.001)T(0.001)S(0.001)TVPNMTDAPTAPK;VS(0.244)KS(0.244)PS(0.088)PAS(0.081)T(0.136)S(0.104)T(0.104)VPNMTDAPTAPK 100.47 1.6471e-06 8253900.0 53944.0 60908.0 72672.0 87713.0 76506.0 71957.0 60999.0 80092.0 64485.0 77437.0 True False 71097.06989509643 80595.31987914268 71708.32179695876 67492.1230023411 65884.46248968747 67457.5174148233 66427.79282927899 67715.62173106591 67893.54545126323 74725.95419998835 0.9514374310272442 1.0785452088500096 0.9596173453342124 0.9031951980393932 0.8816811132764062 0.9027320980644477 0.8889520855297334 0.9061861097128214 0.9085671260825976 1.0 16.189321793812162 -5.541598917559366 4.3676425510925965 0.9070949251953799 1.016799276535855 0.47733724762079155 0.04225163338964406 0.13560257483684848 6.213826793839138 0.01068059522080208 0.020478453808752788 2.8734330484440036e-06 5.541598917559366 0.10970435134047496 VS(ph)KSPSPASTSTVPNMTDAPTAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSKSPSPASTSTVPNMTDAPTAPK 24 1 Q659A1 Q659A1 ICE2 Little elongation complex subunit 2 1 VS(0.313)KS(0.278)PS(0.068)PAS(0.085)T(0.085)S(0.085)T(0.085)VPNMTDAPTAPK 73.107 0.00064163 11926000.0 28375.0 30384.0 28670.0 41962.0 40947.0 39141.0 37214.0 41554.0 39677.0 36045.0 True False 33178.32706820416 33400.32271913948 29353.60153158048 39611.00518263952 32923.72929049897 37088.37705620751 33688.82051397172 40463.251530102396 40257.20106349062 42579.67316793699 0.7792057711985408 0.7844194244377228 0.6893806210256235 0.9302796906498354 0.7732264444737669 0.8710347989269092 0.7911949061022809 0.9502950238841127 0.9454558494311032 1.0 15.377877255577182 -7.785270145668568 0.5060081950346749 1.0113127502997343 0.7701014835945863 0.5840729203839629 0.06219443958987053 0.6146538974271993 0.36704098421528875 0.062344268838661634 0.04152291047774655 1.6395695889095732e-08 7.785270145668568 -0.24121126670514803 VS(ph)KSPSPASTSTVPNMTDAPTAPK ddPTM_PC-9_Lapatinib_30min_R1 1 VSKSPSPASTSTVPNMTDAPTAPK 24 1 Q659A1 Q659A1 ICE2 Little elongation complex subunit 2 1 VS(0.397)KS(0.397)PS(0.162)PAS(0.006)T(0.014)S(0.014)T(0.011)VPNMTDAPTAPK 57.073 0.0031136 10939000.0 34800.0 30924.0 39382.0 36419.0 38758.0 30215.0 31594.0 33210.0 37455.0 34019.0 True False 34303.74561846158 30852.397377964917 36144.163978916185 39097.37475022254 36478.33064115983 28922.774884605136 33229.782729370716 34753.0578390656 33236.423481364625 39899.13882253183 0.859761554529833 0.7732597316246325 0.9058883235470953 0.9799052286347464 0.9142636086310665 0.7248972217984784 0.8328446104356819 0.871022755494659 0.8330110489150548 1.0 15.284069987403822 -10.688399930622086 5.002063010190955 1.0000096777288825 0.855489521499869 0.2889586666595315 0.06824030567303221 7.969524309219467e-06 1.329556086148033e-06 0.07149618445511421 0.017339210931920757 2.0492741857487978e-11 10.688399930622086 -0.14452015622901349 VS(ph)LPPIPAVSNIK ddPTM_PC-9_AZD4547_30min_R2 2 VSLPPIPAVSNIK 13 0 A0A0D9SG79;Q9NZ09-2;Q9NZ09;Q9NZ09-3;Q9NZ09-4 A0A0D9SG79 UBAP1 Ubiquitin-associated protein 1 1 VS(0.998)LPPIPAVS(0.002)NIK;VS(1)LPPIPAVSNIK 71.933 0.024755000000000003 6075600.0 21791.2 28407.0 31119.0 27170.0 33076.0 42736.0 37161.0 38864.0 36274.0 27508.0 True False 28720.348314882584 37589.00722083807 30706.341727206614 20906.376272315494 28483.968333318968 40063.71116416589 40468.25700960403 32858.46180587501 38191.3695851613 26544.953292783575 1.081951359947972 1.4160509836367616 1.1567675930156691 0.7875838409555248 1.073046466465719 1.5092778925724266 1.5245179210997368 1.2378421405927962 1.4387431450310324 1.0 14.696149982516884 -6.746229265509371 24.997762458199258 1.3683439653847507 1.1059223413358712 0.2565590280525878 0.20091705969479398 328.47264086361514 539842.6034421686 0.06883856748580083 0.06858981120505482 1.793786430984869e-07 6.746229265509371 -0.2624216240488795 VS(ph)LPPIPAVSNIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSLPPIPAVSNIK 13 0 A0A0D9SG79;Q9NZ09-2;Q9NZ09;Q9NZ09-3;Q9NZ09-4 A0A0D9SG79 UBAP1 Ubiquitin-associated protein 1 1 VS(1)LPPIPAVSNIK 132.31 5.7685e-05 3958800.0 28230.0 32588.0 29464.0 25887.0 19616.0 15805.0 20039.0 22337.0 14613.0 12498.0 True False 33008.781432084696 35823.12127341093 30166.533502842252 24436.635316786374 15772.385614634226 14976.157976887655 18140.760850203667 21750.677418007806 14826.687479920076 14763.788465886431 2.2357934420664174 2.426417945243845 2.0432786322119 1.6551737633772157 1.068315605515365 1.0143844861697884 1.2287334576839914 1.473244991843757 1.0042603573045619 1.0 13.8497753516006 -5.8681566474855025 1.9593750175661528 1.1532212498406433 2.320165560508743 0.9144872292849344 0.15219815385948565 0.08970291929172787 0.7021368984059346 0.049542482407114716 0.08895481043988043 1.3547006915822312e-06 5.8681566474855025 1.1669443106680994 up VS(ph)LPPIPAVSNIK ddPTM_PC-9_Lapatinib_30min_R1 2 VSLPPIPAVSNIK 13 0 A0A0D9SG79;Q9NZ09-2;Q9NZ09;Q9NZ09-3;Q9NZ09-4 A0A0D9SG79 UBAP1 Ubiquitin-associated protein 1 1 VS(1)LPPIPAVSNIK;VS(1)LPPIPAVSNIK 118.24 0.00024635 8180500.0 22036.0 41575.0 30913.0 35983.0 35157.0 34911.0 34767.0 43624.0 35557.0 39339.0 True False 21721.762599092523 41478.735641860396 28371.452467630796 38629.30985576917 33089.13438132143 33417.93791151583 36567.06514376249 45650.930297241684 31552.19622819071 46138.69373407741 0.47079275205073967 0.8990010831456368 0.6149166821052853 0.8372432492001413 0.7171666924952895 0.724293108602548 0.7925466064236352 0.9894283214941677 0.6838554296756496 1.0 15.493689538965974 -5.377616451243671 0.058468768784996517 1.4108214069275502 3.957025124529247e-10 0.3466884892785389 0.12741882635707732 164.20872917762188 1.8699647030484512 15.61872813488576 30.88798704519107 4.191635875523109e-06 5.377616451243671 -1.4108214065318476 VS(ph)NSPEPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSNSPEPQK 9 0 O60271;O60271-3;D6RHI8 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 VS(0.511)NS(0.489)PEPQK 91.31299999999999 0.0078972 5545100.0 23729.0 36680.0 44169.0 37563.0 42862.0 29976.0 42971.0 29701.0 32886.0 27208.0 True False 27745.851030886897 40321.347990325055 45222.15647186532 35458.466890889096 34463.4987874415 28404.005790267896 38900.475796901126 28921.380220810785 33366.89553580041 32140.5950215905 0.8632650083873237 1.2545302276836854 1.407010556011401 1.1032299454029961 1.0722732035387206 0.883742375372561 1.2103222037665968 0.8998396016434294 1.038154256739371 1.0 14.97210901754664 -6.202552326412444 3.212826541481843 1.0130033510166956 1.1890616355848738 0.17097811999916168 0.1525261114204065 0.4106700783760456 8.449682383440937 0.04786017748008006 0.06210832215783326 6.272601153578381e-07 6.202552326412444 0.17605828456817818 VS(ph)NSPEPQKAVEQEDELSDVSQGGSK ddPTM_PC-9_Lapatinib_30min_R1 1 VSNSPEPQKAVEQEDELSDVSQGGSK 26 1 O60271;O60271-3;D6RHI8 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 VS(0.619)NS(0.381)PEPQKAVEQEDELSDVSQGGSK 105.73 0.00016491 0.0 29106.0 14547.0 12726.0 14194.0 11511.0 12621.0 11829.0 10475.0 11477.0 4455.2 True False 28690.943102613306 14513.317315265012 11679.717403780602 15237.87410979595 10833.945611496738 12081.229250987975 12441.447740258478 10961.706740867574 10184.339401832123 5225.275383819156 5.490800196188528 2.7775219962966284 2.2352348050302933 2.9161858448613636 2.073373136475384 2.3120751278294924 2.3810128321246524 2.097823738594167 1.9490531414611083 1.0 12.351291357147643 -3.010754571710513 1.165734799178074 2.1501515649397014 199.99993742887176 0.830667438123622 0.4546391173959896 34.222778717593414 1.0276217573785895 0.12975181228618923 17207.6175144362 0.0009755407791099232 3.010754571710513 197.84978586393206 up VS(ph)PAGGTLDDKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSPAGGTLDDKPK 13 1 C9JA69;Q8WY36-2;Q8WY36 C9JA69 BBX HMG box transcription factor BBX 1 VS(0.983)PAGGT(0.017)LDDKPK;VS(0.945)PAGGT(0.055)LDDKPK 67.846 0.016131 11402200.0 94954.0 134373.0 108469.0 98650.0 110194.0 62300.0 92528.0 69330.0 60601.0 81530.0 True False 111027.83677301319 147712.6633997802 111055.31233097299 93122.96032761526 88602.27673424767 59032.878327118 83763.07799529121 67510.16096120689 61487.17497917171 96310.74360887527 1.1528084262738647 1.533709094798933 1.153093706575213 0.9669010625210639 0.919962544304172 0.6129417769512266 0.8697168649788334 0.7009618909741826 0.6384248804980207 1.0 16.55540912140534 -5.869339340957715 1.4782017950141104 0.7606138914952401 1.3516090930073816 0.7035595456067831 0.14463677117673882 0.2016305695038638 0.8953023878338014 0.04667467132431402 0.0944870111446605 1.3510165184719581e-06 5.869339340957715 0.5909952015121416 VS(ph)PAGGTLDDKPK ddPTM_PC-9_Lapatinib_30min_R1 1 VSPAGGTLDDKPK 13 1 C9JA69;Q8WY36-2;Q8WY36 C9JA69 BBX HMG box transcription factor BBX 1 VS(0.979)PAGGT(0.021)LDDKPK 59.513000000000005 0.028832999999999998 11721000.0 40755.0 62509.0 58327.0 56472.0 76475.0 68042.0 75557.0 95885.0 65137.0 60148.0 True False 40173.82622644835 62364.264251041546 53531.57920873103 60625.13926506956 71976.89085563483 65132.00227364902 79468.97175675968 100340.16714540211 57800.58513698167 70544.50165782792 0.5694820330762163 0.8840414601486003 0.7588341819803747 0.8593885822473925 1.0203047603164686 0.9232753899030726 1.1265083725762128 1.4223669426725327 0.8193492586756103 1.0 16.106246020981352 -6.098975025270978 0.7935066899046499 1.112723458751679 0.6856243564697545 0.4471806586929029 0.16154300545262004 0.6609454532681913 0.8589051276539457 0.08347782395263889 0.1774884595547567 7.962051360227086e-07 6.098975025270978 -0.4270991022819245 VS(ph)PAHS(ph)PPENGLDK ddPTM_PC-9_AZD4547_30min_R2 1 VSPAHSPPENGLDK 14 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 2 VS(1)PAHS(1)PPENGLDK 92.439 0.0050997 0.0 16815.0 20146.0 22134.0 12852.0 17711.0 20584.0 24206.0 26854.0 23078.0 18465.0 True False 22161.820226272564 26657.80052349787 21840.488697901328 9889.169961420639 15252.133364113328 19296.879226019995 26360.287106764492 22704.331343530466 24297.85596532921 17818.545970308576 1.2437502062851413 1.4960704744325566 1.2257166625320943 0.5549930941558966 0.8559695830135794 1.0829659871335628 1.4793736341163415 1.2741966365472905 1.363627313127415 1.0 14.12109199435474 -7.140521102293746 8.912433168037728 1.301782647571168 1.0675294301167146 0.124964529726583 0.25969492708189856 0.714065301013868 49.13528320241683 0.11091999447183316 0.0859026531976419 7.235672434188911e-08 7.140521102293746 -0.23425321745445338 VS(ph)PAHSPPENGLDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSPAHSPPENGLDK 14 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 VS(0.992)PAHS(0.008)PPENGLDK 77.324 0.008648999999999999 4003200.0 14427.0 18726.0 13219.0 16072.0 17777.0 16863.0 21655.0 10891.0 13705.0 13158.0 True False 16869.20615376144 20584.9935241774 13534.191093336663 15171.537946127028 14293.724463262273 15978.674594385104 19603.681631376836 10605.122789968354 13905.409697687308 15543.441241329305 1.0852941695373728 1.3243523879025474 0.8707332490407507 0.9760732974488685 0.9195984493611304 1.0280010935994361 1.261218884995141 0.6822892450463166 0.8946159014461647 1.0 13.924018324233547 -5.266268653970413 24.997640660326045 0.955884688702862 1.204823282088461 0.31717337777127985 0.14715084884483692 442.4258935181034 2290127.797826667 0.03909147354833372 0.08565745207577745 5.416657130755517e-06 5.266268653970413 0.24893859338559898 VS(ph)PATPK ddPTM_PC-9_AZD4547_30min_R2 1 VSPATPK 7 0 J3KNZ9;Q9HAH7;Q9HAH7-1 J3KNZ9 FBRS Probable fibrosin-1 1 VS(0.996)PAT(0.004)PK 76.17 0.031649000000000004 10848000.0 128460.0 110020.0 139030.0 147920.0 150540.0 167390.0 136360.0 135300.0 117120.0 145820.0 True False 169307.60786601107 145581.81344163785 137186.3713594117 113819.32934121846 129640.11950954898 156923.0768384902 148495.77583567725 114392.49388469767 123310.72409478106 140714.88618415373 1.20319613977755 1.034587152713287 0.9749243671339488 0.808864878675757 0.9212964102453867 1.1151846197219304 1.055295426536043 0.8129381118568514 0.876316127160876 1.0 17.10241543334555 -4.816457176547587 2.024580630724808 0.9431981909045786 1.2654382210191915 0.4202592298857145 0.09280393866967306 0.7289788548696841 3.5225835420709455 0.02752036288594074 0.4302061370757191 1.5259588540176515e-05 4.816457176547587 0.3222400301146129 VS(ph)PATPK ddPTM_PC-9_Lapatinib_30min_R1 1 VSPATPK 7 0 J3KNZ9;Q9HAH7;Q9HAH7-1 J3KNZ9 FBRS Probable fibrosin-1 1 VS(0.999)PAT(0.001)PK 70.816 0.043012 21409000.0 102990.0 131140.0 126400.0 144250.0 138950.0 155760.0 127840.0 143580.0 151280.0 114620.0 True False 101521.34371394714 130836.35338721768 116007.87991811012 154858.62620389374 130777.23418621071 149098.50789429434 134458.92967407603 150251.25096456014 134241.25335097694 134431.91427845022 0.7551878157716695 0.9732536659131029 0.8629489547982021 1.1519483824587475 0.972813895332402 1.109100533861811 1.0002009596885593 1.117675455051121 0.9985817286877403 1.0 17.03651615054116 -3.938260958157906 0.7591236599968184 1.0502057105307334 4.781271862958073e-14 0.5525240188131229 0.07587977441375314 5.863159602040921 1.0082986684363762 0.026458397555144515 7.059884907167555 0.00011527603809024702 3.938260958157906 -1.0502057105306857 VS(ph)PENLVDK ddPTM_PC-9_AZD4547_30min_R2 4 VSPENLVDK 9 0 O75376-2;O75376;A0A088AWL3;E7EVK1;J3KS29;J3QKP0 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 VS(1)PENLVDK;VS(1)PENLVDK;VS(1)PENLVDK;VS(1)PENLVDK 152.96 7.4797e-05 156205000.0 313350.0 339350.0 339417.0 299075.0 306007.0 396452.0 349353.0 379486.0 375549.0 341101.0 True False 412988.7819151065 449038.25114906183 334916.108808872 230127.87941268896 263523.210115309 371661.79376768775 380444.74021356273 320845.15842075716 395399.75344152085 329159.15781306435 1.2546780853949402 1.3641979586181803 1.0174898703534694 0.6991386201789436 0.8005951037976855 1.1291248775729383 1.1558078552067035 0.9747417041423199 1.2012418432121392 1.0 18.328425811180608 -5.294838886874198 7.497917736971013 0.9885346395737925 1.309443315456277 0.41494365698963864 0.14802734263690087 0.21861727750660012 42.80254864473999 0.0427875333785501 0.09170768395147962 5.071788248966251e-06 5.294838886874198 0.3209086758824845 VS(ph)PENLVDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VSPENLVDK 9 0 O75376-2;O75376;A0A088AWL3;E7EVK1;J3KS29;J3QKP0 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 VS(1)PENLVDK;VS(1)PENLVDK;VS(1)PENLVDK;VS(1)PENLVDK 166.24 0.00093229 105981700.0 106491.0 133333.0 111639.0 108908.0 127869.0 96604.0 117860.0 82469.0 91588.0 88762.0 True False 124517.82300687667 146569.41907290128 114300.89715326516 102806.23784449973 102813.98736529677 91537.91617837729 106695.44756749374 80304.27613312825 92927.30123252726 104853.84796039459 1.187536990096058 1.3978449234239214 1.0900973056939114 0.9804717694607805 0.9805456772948541 0.8730048344334773 1.0175634909249565 0.7658686609523457 0.8862555169899704 1.0 16.678020281331627 -5.596084071989855 2.1147703232076793 0.9159485978535992 1.295339977247894 0.7346242842951081 0.08670827718934243 0.15032378227815224 1.343459305276516 0.02496754924505161 0.05741802732459211 2.5346379204169987e-06 5.596084071989855 0.3793913793942948 VS(ph)PENLVDK ddPTM_PC-9_Lapatinib_30min_R1 4 VSPENLVDK 9 0 O75376-2;O75376;A0A088AWL3;E7EVK1;J3KS29;J3QKP0 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 VS(1)PENLVDK;VS(1)PENLVDK;VS(1)PENLVDK;VS(1)PENLVDK 162.93 0.00017226 158804000.0 126033.0 183728.0 170176.0 154953.0 181021.0 180657.0 187962.0 186886.0 182646.0 156394.0 True False 124235.74630837822 183302.58910421433 156184.78617835653 166348.76052805485 170373.7006809792 172930.72124203583 197693.75265487077 195569.40582088535 162074.48413235415 183426.49451809394 0.6773053513058502 0.9993244955468121 0.8514843321227503 0.9068960346491577 0.9288391032527357 0.9427794043405068 1.077781883005835 1.0662004217803638 0.8835936409195589 1.0 17.484842514401343 -3.3981056071384415 0.4694900639214236 0.9979578651804073 1.8085292232908977e-18 0.4753514799211057 0.08028274472447515 15.715000078466351 0.9680801585438926 0.05001900026562031 11.496243276992697 0.00039984750725087227 3.3981056071384415 -0.9979578651804073 VS(ph)PFGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSPFGLR 7 0 J3KNZ9;H3BRE6 J3KNZ9 FBRS 1 VS(1)PFGLR;VS(1)PFGLR 82.75 0.022022999999999997 28011000.0 17657.9 29911.0 96137.0 51732.0 86297.0 77529.0 40858.0 44390.0 63464.0 35936.0 True False 20647.033710577696 32880.36640508758 98429.27068160294 48833.62375740689 69387.72233819783 73463.24275799567 36987.63445369632 43224.809535092754 64392.04093790783 42450.91233078053 0.48637432217462234 0.7745502887872333 2.3186609021411617 1.1503551060785648 1.6345401907389825 1.7305456755691104 0.8713036404373607 1.0182304021709112 1.5168588235786422 1.0 15.3735079392394 -11.129167793234824 2.5187616390878036 0.9701479818909956 1.2941895337535931 0.025140803117891353 0.5102580843399716 46009674.42117146 39348957.23941869 9067961.936921924 0.13317626840195723 7.42732121808198e-12 11.129167793234824 0.32404155186259753 VS(ph)PFGLR ddPTM_PC-9_Lapatinib_30min_R1 1 VSPFGLR 7 0 J3KNZ9;H3BRE6 J3KNZ9 FBRS 1 VS(1)PFGLR 80.219 0.025726 17215000.0 15349.0 14491.0 50249.0 17384.0 24070.0 31897.0 16760.0 17799.0 40584.0 14735.0 True False 15130.120445338138 14457.446979824388 46117.72118674926 18662.477351323992 22654.249923440762 30532.83966553867 17627.750792690174 18626.006518444094 36013.00255153392 17281.92511684666 0.8754881382160998 0.8365646119905396 2.668552309707271 1.0798841694512118 1.310863793834929 1.7667499111991194 1.020010830593543 1.0777738239524717 2.0838536394552447 1.0 14.076976314749356 -10.370685146987746 7.437010461448581 1.0000000000823168 1.4094006804685408 0.046338845166613574 0.5622404585528237 1.0013484958171654e-08 1.0741153660112144e-09 0.5360795398085769 0.13001838625666295 4.259070735782925e-11 10.370685146987746 0.409400680386224 VS(ph)PGLPSPNLENGAPAVGPVQPR ddPTM_PC-9_AZD4547_30min_R2 1 VSPGLPSPNLENGAPAVGPVQPR 23 0 C9JRJ5;Q9UGP4 C9JRJ5 LIMD1 LIM domain-containing protein 1 1 VS(1)PGLPSPNLENGAPAVGPVQPR 176.44 3.3168e-14 7217500.0 15452.0 14216.0 20685.0 24001.0 18930.0 21518.0 18420.0 20820.0 16016.0 17507.0 True False 20365.414578433756 18811.043990968217 20410.703384661098 18467.94026175355 16301.896255584963 20172.47605837049 20059.344315731727 17602.747396004488 16862.573062687952 16894.085258716077 1.2054760152182098 1.1134692232752368 1.2081567644587747 1.0931601195883323 0.9649469625574674 1.1940555377488111 1.1873590081109964 1.0419473517764328 0.998134720196711 1.0 14.04423061650034 -1.5228787452854016 0.07641661612110653 0.8801694452122293 1.6668533809982513 0.33078974568145225 0.07385652130540138 289.1949725612413 1.6250032860259522 2.6620277119329683 24.1558205857407 0.029999999999650192 1.5228787452854016 0.786683935786022 VS(ph)PGLPSPNLENGAPAVGPVQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSPGLPSPNLENGAPAVGPVQPR 23 0 C9JRJ5;Q9UGP4 C9JRJ5 LIMD1 LIM domain-containing protein 1 1 VS(1)PGLPSPNLENGAPAVGPVQPR 228.11 6.895799999999999e-47 3768500.0 11414.0 11063.0 13348.0 12944.0 16012.0 11692.0 10853.0 10335.0 10862.0 8277.0 True False 13346.16476322404 12161.26152718009 13666.26694257189 12218.789645014205 12874.563543103759 11078.850937410341 9824.925271084398 10063.717200837655 11020.836201114887 9777.554579304053 1.3649798275198166 1.2437937756871826 1.3977182977325429 1.2496774675006637 1.316746783531649 1.1330901655983303 1.0048448404349093 1.0292672998358217 1.1271567048515856 1.0 13.255257968913227 -6.887973815808022 3.0827502710548256 1.0437171493856174 1.3134040814541306 0.8498415175020817 0.054744036563910865 0.09093953437941371 1.7283167895228055 0.019912296847723217 0.017278389418301267 1.2942738725909815e-07 6.887973815808022 0.26968693206851313 VS(ph)PGLPSPNLENGAPAVGPVQPR ddPTM_PC-9_Lapatinib_30min_R1 1 VSPGLPSPNLENGAPAVGPVQPR 23 0 C9JRJ5;Q9UGP4 C9JRJ5 LIMD1 LIM domain-containing protein 1 1 VS(0.707)PGLPS(0.293)PNLENGAPAVGPVQPR 77.668 0.00029617 2932500.0 8040.3 14058.0 11787.0 8740.7 12473.0 10882.0 9809.5 9861.2 10974.0 8032.6 True False 7925.643847589562 14025.449564720946 10817.918359135776 9383.520236120436 11739.362662861515 10416.602227180983 10317.387911747872 10319.387352080505 9737.992558656942 9421.02420723329 0.8412719968922697 1.4887393616877094 1.1482741282874507 0.996019119547102 1.2460813606495404 1.1056761980489667 1.095145037821511 1.0953572695585974 1.0336447868566445 1.0 13.201668195707544 -7.962662673697522 0.6909323555385372 0.9984713399964207 1.1597957552834584 0.07648258500576421 0.15696042048253395 1.652097538062828 1.630232610864724 0.14433724388750618 0.06693436136602521 1.0897762184144598e-08 7.962662673697522 0.16132441528703767 VS(ph)PGQAAPAMAR ddPTM_PC-9_AZD4547_30min_R2 1 VSPGQAAPAMAR 12 0 Q96HA7-2;Q96HA7 Q96HA7-2 TONSL Tonsoku-like protein 1 VS(1)PGQAAPAMAR 69.314 0.032436 3914100.0 3047.3 3141.5 7245.8 10667.0 7010.7 6504.8 7232.4 8550.3 9372.4 3270.4 True False 4016.278012222444 4156.92843961921 7149.715957678385 8207.887953507152 6037.385318490732 6098.053827701848 7876.069588984696 7229.047601347598 9867.80592986617 3155.9042914322886 1.2726235149544665 1.3171909081351172 2.2655046850085334 2.600803825321981 1.9130444908868578 1.9322683023870417 2.495661738021272 2.29064221655047 3.126776042180837 1.0 11.623837738312025 -5.257306982153052 8.322309469757032 2.2541936823058895 1.2924224450583444 0.32197748525121017 0.5229916098927561 0.12362376224222409 98.77189001323295 0.12849904715445823 0.3066741647511196 5.529591104968722e-06 5.257306982153052 -0.9617712372475451 VS(ph)PGQAAPAMAR ddPTM_PC-9_Lapatinib_30min_R1 1 VSPGQAAPAMAR 12 0 Q96HA7-2;Q96HA7 Q96HA7-2 TONSL Tonsoku-like protein 1 VS(1)PGQAAPAMAR 97.95700000000001 0.0038085999999999997 7311400.0 9162.9 10718.0 13620.0 8913.3 14107.0 11248.0 10244.0 10950.0 12852.0 9865.4 True False 9032.235365729934 10693.183129511961 12500.216174720397 9568.813815897154 13277.253995429108 10766.949260368643 10774.384195723042 11458.776974940329 11404.472422440225 11570.621245180804 0.7806180130122127 0.9241667238883738 1.0803409695850836 0.8269922256665857 1.1474970715992558 0.930542019500734 0.9311845896097067 0.9903337713792111 0.9856404579132014 1.0 13.498178706681117 -4.833591166634679 3.5950705085373236 0.983336828378921 0.7683629310251767 0.3655747453166628 0.08187586350103629 0.258094069021069 5.600150678402572 0.019375377468131772 0.13648974695550928 1.466928118597798e-05 4.833591166634679 -0.21497389735374428 VS(ph)PKSPPTDQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSPKSPPTDQK 11 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 VS(0.561)PKS(0.438)PPT(0.002)DQK 61.423 0.028023000000000003 20142000.0 37079.0 24270.0 33251.0 54157.0 49640.0 46584.0 46937.0 59819.0 44797.0 32162.0 True False 43355.74235636798 26679.365205157832 34043.82994511973 51122.75886936299 39913.39834372159 44141.05303355484 42490.78756554765 58248.81463346957 45452.07137740228 37992.716005748065 1.141159330378184 0.7022231630168637 0.8960620225195037 1.3455936885804223 1.0505539624406672 1.1618293629462175 1.1183929982557461 1.5331574248247186 1.1963364601395083 1.0 15.213435229956259 -5.745065901081385 24.480433821832555 1.2117302088931974 0.8920554251388941 0.36270406297470614 0.17366242625649575 186.15710016257245 278325.52079284034 0.04660510405955412 0.08039262826675826 1.798597970042901e-06 5.745065901081385 -0.31967478375430325 VS(ph)PPAPGSAPETPEDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSPPAPGSAPETPEDK 16 0 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 VS(1)PPAPGSAPETPEDK;VS(0.998)PPAPGS(0.002)APETPEDK 148.18 3.0299999999999998e-05 9827500.0 24882.8 32190.0 24482.4 22899.4 26031.0 17645.0 19033.6 14300.9 14336.0 16885.0 True False 29094.966582298137 35385.61046370127 25066.153266019046 21616.420858856498 20930.41241509705 16719.665137752778 17230.599616669304 13925.516528056043 14545.636878952582 19946.116838413538 1.458678238877311 1.774060121594863 1.2566933939615257 1.0837408120073868 1.0493477294180835 0.8382416122998413 0.8638573490898984 0.6981567711083178 0.7292465494305961 1.0 14.283820285733636 -5.774830123972975 0.9504020820750094 0.8043799419239511 1.6795961976437979 0.841796181828257 0.1281131341083477 0.23969625232152622 0.40526241246014494 0.05132603473236326 0.1569300217000108 1.6794608174885096e-06 5.774830123972975 0.8752162557198467 VS(ph)PPAPGSAPETPEDK ddPTM_PC-9_Lapatinib_30min_R1 1 VSPPAPGSAPETPEDK 16 0 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 VS(1)PPAPGSAPETPEDK 116.78 0.0016335000000000002 0.0 6270.5 13794.0 10767.0 10363.0 9176.1 6673.8 7706.0 6380.2 6894.2 5202.7 True False 6181.08152013113 13762.060840500832 9881.77882182192 11125.129589954584 8636.379838906712 6388.377131387654 8104.978974252422 6676.647384065228 6117.702596855539 6101.979762838014 1.012963293941887 2.2553435729685436 1.619438150549672 1.823200014150869 1.4153406229734784 1.0469351554218262 1.328253991206752 1.0941772414138486 1.0025766775093683 1.0 12.57506167990123 -6.528341227034126 3.4100268034650454 1.1160748144608112 1.7125796431629525 0.45789336193460883 0.2976270190710639 0.20839797378047498 5.125817505370864 0.09578432646902887 0.10137197724069079 2.9625028237077325e-07 6.528341227034126 0.5965048287021413 VS(ph)PPASPGP ddPTM_PC-9_AZD4547_30min_R2 1 VSPPASPGP 9 0 A0A0C4DGU2;Q9Y4U1 A0A0C4DGU2 MMACHC Methylmalonic aciduria and homocystinuria type C protein 1 VS(0.997)PPAS(0.003)PGP 79.986 0.025997000000000003 6687100.0 19919.0 16602.0 17345.0 30039.0 28634.0 27995.0 21619.0 28521.0 19833.0 26993.0 True False 26252.827659061753 21968.271830195165 17114.993966978338 23113.972647923638 24658.663358817736 26244.46822446705 23543.04911844757 24113.73479737961 20881.331890128014 26047.983286029747 1.0078641164186355 0.8433770702692887 0.6570563939265726 0.8873613129320572 0.9466630521082551 1.0075431919730493 0.9038338538505727 0.9257428697104728 0.8016486981288586 1.0 14.668884058545665 -5.993078889501856 24.999008191275486 0.9285199816087167 0.8260573049693872 0.16439785976558996 0.09503245263148753 300.7050852234769 1086130.348150507 0.027529233063591372 0.04073314603685339 1.0160641082734495e-06 5.993078889501856 -0.10246267663932951 VS(ph)PPASPGP ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSPPASPGP 9 0 A0A0C4DGU2;Q9Y4U1 A0A0C4DGU2 MMACHC Methylmalonic aciduria and homocystinuria type C protein 1 VS(1)PPASPGP;VS(0.972)PPAS(0.028)PGP 104.01 0.0036703000000000005 9268600.0 51580.0 56351.0 55602.0 60653.0 64271.0 52555.0 57356.0 51793.0 47122.0 44044.0 True False 60311.475248562776 61945.15486921498 56927.76255175929 57254.809049679105 51677.558923233904 49798.92328221006 51922.82445851994 50433.48862921964 47811.07010393441 52028.828547887846 1.1591934112652853 1.190592919312032 1.0941580685285355 1.1004439394014265 0.9932485578772808 0.9571409672692254 0.9979625893504341 0.9693373853843386 0.9189342031779292 1.0 15.667023604312089 -6.0005609278969585 1.129865924488443 0.9637351784989292 1.1761166441887558 0.8934723560842825 0.02836072265477906 0.14703194975906492 0.3818335010618289 0.01093044863378194 0.021871911084564922 9.98709249522124e-07 6.0005609278969585 0.21238146568982663 VS(ph)PPASPGP ddPTM_PC-9_Lapatinib_30min_R1 2 VSPPASPGP 9 0 A0A0C4DGU2;Q9Y4U1 A0A0C4DGU2 MMACHC Methylmalonic aciduria and homocystinuria type C protein 1 VS(1)PPASPGP;VS(1)PPASPGP 117.53 0.0024896999999999996 9238200.0 60963.0 59802.0 62205.0 55263.0 55830.0 46427.0 37542.0 36633.0 46239.0 32292.0 True False 60093.656440755025 59663.53214322396 57090.745018243906 59327.225371963745 52546.18916600323 44441.42543662296 39485.74106558324 38335.102915341464 41031.07690174394 37873.629173614674 1.5866886208681665 1.5753317927290051 1.5074009611420385 1.56645208464192 1.3874083448704844 1.1734134384877977 1.0425655509425453 1.0121845661954225 1.0833679738916848 1.0 15.208906051099566 -6.727013801604637 1.610450861866485 1.0301438086213464 1.5634166740520696 0.9845635370619721 0.02995504128883644 0.040439128458554366 0.2175495475560401 0.01270094703113007 0.01187120287143989 1.8749349228716866e-07 6.727013801604637 0.5332728654307233 VS(ph)PPASPTLEVELGSAELPLQGAVGPELPPGGGHGR ddPTM_PC-9_AZD4547_30min_R2 2 VSPPASPTLEVELGSAELPLQGAVGPELPPGGGHGR 36 0 Q7Z6J0 Q7Z6J0 SH3RF1 E3 ubiquitin-protein ligase SH3RF1 1 VS(0.905)PPAS(0.047)PT(0.048)LEVELGSAELPLQGAVGPELPPGGGHGR;VS(0.802)PPAS(0.091)PT(0.106)LEVELGSAELPLQGAVGPELPPGGGHGR 90.331 1.2324e-12 21281800.0 11161.0 11984.1 16545.6 22241.0 23031.1 6177.099999999999 10371.3 18352.0 18489.0 17721.5 True False 14709.96583677836 15857.725963151546 16326.194533297014 17113.681070024606 19833.629310723878 5790.844960505638 11294.325608129664 15516.120087006437 19466.290793958404 17101.075679004793 0.8601778106179584 0.9272940638827929 0.9546881634668684 1.0007371110014611 1.159788406472809 0.33862460287308893 0.6604453322194141 0.9073183686366452 1.138307973097705 1.0 14.061799454833563 -4.457623197603746 14.561260118493454 0.8844322452761756 0.6439475137263393 0.0 0.22858905323508183 9833877.53524614 58828963.89225779 0.06049626980346096 69384458.485894 3.486396704569724e-05 4.457623197603746 -0.2404847315498363 VS(ph)PPASPTLEVELGSAELPLQGAVGPELPPGGGHGR ddPTM_PC-9_Lapatinib_30min_R1 2 VSPPASPTLEVELGSAELPLQGAVGPELPPGGGHGR 36 0 Q7Z6J0 Q7Z6J0 SH3RF1 E3 ubiquitin-protein ligase SH3RF1 1 VS(0.586)PPAS(0.197)PT(0.216)LEVELGSAELPLQGAVGPELPPGGGHGR;VS(0.871)PPAS(0.06)PT(0.07)LEVELGSAELPLQGAVGPELPPGGGHGR 102.09 4.5224e-17 42761000.0 11047.8 12544.4 14973.400000000001 13718.5 12027.9 6746.7 6379.7 5223.5 5637.799999999999 4155.3 True False 10890.256346081615 12515.354212525632 13742.34485099547 14727.40425357446 11320.442569761244 6458.159368325848 6710.0096498881585 5466.202879324272 5002.811595334069 4873.538068410785 2.2345688477678856 2.5680222534112205 2.8197881412008177 3.021912222053685 2.322838646349742 1.325148029557055 1.3768251228775628 1.1216087373473107 1.026525601135899 1.0 12.25075379834231 -6.724154349293992 2.9897640008969266 1.1602416924290335 2.6707826765493192 0.9206230753414381 0.21123589139607224 0.07128311468765364 1.3052262996603696 0.08287345637936057 0.07876044152011095 1.8873204716936465e-07 6.724154349293992 1.5105409841202857 up VS(ph)PPQPPPPQPPRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSPPQPPPPQPPRK 14 1 Q15637-5 Q15637-5 SF1 Splicing factor 1 1 VS(1)PPQPPPPQPPRK;VS(1)PPQPPPPQPPRK 99.566 0.0023556 6466400.0 30189.0 46451.0 37652.0 39487.0 45192.0 34407.0 43351.0 35475.0 38900.0 32996.0 True False 35299.40144007101 51062.34829603569 38549.76647600515 37274.67140858127 36336.95201348645 32602.63634993821 39244.479445939374 34543.818838869454 39468.8389084302 38977.91360380773 0.9056257294547092 1.3100328769533587 0.9890156478831963 0.9563023764550582 0.9322446650899425 0.8364387247949895 1.0068388945812021 0.8862408385936514 1.0125949610749436 1.0 15.250369248134003 -5.504763731465532 24.380099802110394 0.9422716132634931 1.1182530693152828 0.2671477338675722 0.10443859630042501 567.0054022266163 763102.5251979196 0.02532728173067533 0.05106323038135269 3.1277805057891546e-06 5.504763731465532 0.17598145605178972 VS(ph)PPQPPPPQPPRK ddPTM_PC-9_Lapatinib_30min_R1 2 VSPPQPPPPQPPRK 14 1 Q15637-5 Q15637-5 SF1 Splicing factor 1 1 VS(1)PPQPPPPQPPRK;VS(1)PPQPPPPQPPRK 108.56 0.00030869 5622400.0 20362.5 24583.0 35852.0 25950.0 30702.0 34107.0 27314.0 32874.0 24984.0 32304.0 True False 20072.127015974842 24526.079573875028 32904.38695272214 27858.449566662308 28896.168722454408 32648.323117300264 28728.185271571576 34401.446052437284 22170.03882681655 37887.70335762568 0.5297794597500963 0.6473361381229947 0.8684714046173362 0.7352900043505862 0.7626793434719621 0.8617129100998706 0.7582456239272006 0.9079844647145466 0.5851512987618019 1.0 15.209442070069466 -5.0315238582361514 3.5404132338531293 0.8019294010130331 0.5410858478334027 0.4233144644109984 0.10690469921548487 0.20492768051635737 5.222556676757928 0.025424898226708206 0.1013284637708044 9.29985424025779e-06 5.0315238582361514 -0.26084355317963037 VS(ph)PSDTTPLVSR ddPTM_PC-9_AZD4547_30min_R2 2 VSPSDTTPLVSR 12 0 H0YJG4;Q9HCK8-2;Q9HCK8 H0YJG4 CHD8 Chromodomain-helicase-DNA-binding protein 8 1 VS(0.944)PS(0.031)DT(0.02)T(0.006)PLVSR;VS(0.876)PS(0.048)DT(0.038)T(0.038)PLVSR 103.11 0.0021982 9902000.0 21758.0 24973.0 31862.0 32361.0 35431.0 29387.0 31584.0 39530.0 30232.0 29957.0 True False 28676.591405485487 33045.033876368136 31439.48906173905 24900.671422466014 30512.017233577975 27549.42624441553 34394.91481368462 33421.54680903252 31830.001800148737 28908.21454820113 0.9919876358213187 1.143101861973154 1.0875624646177062 0.861370091914428 1.0554791331959532 0.9529964639801611 1.1897972722021641 1.1561262890624369 1.101071176397832 1.0 14.819191886254396 -7.261862463650129 24.9999990855685 1.124759207326992 1.0193184783070528 0.22821631586801505 0.08527618212966047 56.46484571097682 3336409.36705785 0.03485167855183246 0.025105665062627947 5.4718922434729016e-08 7.261862463650129 -0.10544072901993928 VS(ph)PSDTTPLVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSPSDTTPLVSR 12 0 H0YJG4;Q9HCK8-2;Q9HCK8 H0YJG4 CHD8 Chromodomain-helicase-DNA-binding protein 8 1 VS(0.99)PS(0.008)DT(0.001)T(0.001)PLVSR;VS(0.688)PS(0.279)DT(0.009)T(0.025)PLVSR 112.02 0.0010031 26765000.0 31797.0 28005.4 38087.0 38788.0 38442.0 35354.0 35259.0 32728.0 28160.2 21779.2 True False 37179.60408062332 30785.59103075924 38995.13852575186 36614.83411239271 30909.566058206008 33499.974002839976 31919.012266945974 31868.924678182393 28571.989651135642 25727.596555947654 1.4451254317429902 1.1965980173784359 1.5156930201759187 1.4231735184734218 1.2014167740460933 1.302102741310887 1.2406527052588985 1.2387058623559999 1.110558057337479 1.0 14.651029067916443 -8.056417778174216 0.44730224357191223 0.9883621973259311 1.3916054709475887 0.6355892899599414 0.0906930287828843 0.6596543209606157 0.35409126923322365 0.1060917144414952 0.07013584540458973 8.781773303067071e-09 8.056417778174216 0.40324327362165757 VS(ph)PSDTTPLVSR ddPTM_PC-9_Lapatinib_30min_R1 4 VSPSDTTPLVSR 12 0 H0YJG4;Q9HCK8-2;Q9HCK8 H0YJG4 CHD8 Chromodomain-helicase-DNA-binding protein 8 1 VS(0.846)PS(0.154)DTTPLVSR;VS(0.9)PS(0.045)DT(0.011)T(0.043)PLVSR;VS(0.999)PS(0.001)DTTPLVSR;VS(0.998)PS(0.002)DTTPLVSR 182.25 0.00061089 98230500.0 108108.0 158333.0 170317.0 109566.0 143883.0 169134.0 170846.0 146658.0 186714.0 128561.0 True False 106566.36009542078 157966.3896664509 156314.19370263215 117623.84914146112 135420.08482486175 161900.533090611 179691.56992410196 153472.26608135112 165684.30313441512 150782.5975532354 0.7067550355590365 1.0476433768205857 1.0366859056625801 0.7800890225407662 0.8981148157833683 1.073734872046161 1.1917261861778177 1.0178380567237948 1.0988290812268209 1.0 17.20211040521574 -6.774053079199676 7.383903599673328 1.0852924493275635 0.9037974958703281 0.4156736285944519 0.10767725864540928 0.1546556841793238 43.875861067473565 0.03770898264984376 0.03457256390830028 1.6824684182672334e-07 6.774053079199676 -0.18149495345723543 VS(ph)PSFSAELK ddPTM_PC-9_AZD4547_30min_R2 2 VSPSFSAELK 10 0 Q13416 Q13416 ORC2 Origin recognition complex subunit 2 1 VS(0.997)PS(0.002)FSAELK;VS(0.895)PS(0.103)FS(0.003)AELK 134.75 0.00011211 17794200.0 46575.0 39707.0 53505.0 67380.0 50847.0 51354.0 43457.0 53879.0 49913.0 56727.0 True False 61384.88117981827 52541.51123729428 52795.48874045404 51846.58201062264 43787.771733107686 48142.82626180677 47324.58881263589 45553.23856625 52551.29928059093 54741.00499635498 1.1213692767223709 0.9598199967427131 0.9644596175018986 0.9471251398120097 0.7999080713995544 0.8794655170290065 0.8645180850404021 0.8321593395898237 0.9599988031657465 1.0 15.74033430109828 -3.62360543199995 0.7715152202049234 0.8842502338053676 2.2537225867088617 0.5497249306765128 0.05928133680438538 9.32924143403867 1.0829557735618929 0.02147071569436796 16.618380937975616 0.0002379000690005327 3.62360543199995 1.369472352903494 VS(ph)PSFSAELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSPSFSAELK 10 0 Q13416 Q13416 ORC2 Origin recognition complex subunit 2 1 VS(0.87)PS(0.115)FS(0.016)AELK;VS(0.999)PS(0.001)FSAELK 151.13 0.00016395 12977700.0 48624.0 53875.0 49100.0 63834.0 61257.0 50564.0 56090.0 54778.0 51450.0 41252.0 True False 56855.08283222411 59223.353952528974 50270.73021278693 60257.58793262028 49254.1305870539 47912.33482716527 50776.749143566194 53340.13554208855 52202.35891616282 48730.66104934766 1.1667209434045878 1.215320142949749 1.0316036994014857 1.2365436182283622 1.0107420980227653 0.9832071594236388 1.0419876941982489 1.0945908467786443 1.071242576892185 1.0 15.572542172901493 -6.278240826920151 24.922328781588497 1.036254836502851 1.1569635075715075 0.5316805458032492 0.05915086972528138 671.4486941704823 995987.0368364793 0.018476947386324657 0.021005684153679774 5.269375806059337e-07 6.278240826920151 0.12070867106865646 VS(ph)PSFSAELK ddPTM_PC-9_Lapatinib_30min_R1 1 VSPSFSAELK 10 0 Q13416 Q13416 ORC2 Origin recognition complex subunit 2 1 VS(0.994)PS(0.006)FSAELK 131.17 0.00018861 7892400.0 23915.0 19051.0 26191.0 23542.0 22329.0 24504.0 20819.0 22691.0 19284.0 21205.0 True False 23573.967714526123 19006.888579989947 24037.67708018368 25273.357213809795 21015.652120503062 23456.021041613923 21896.905951850644 23745.30669756812 17112.03285047753 24870.255996113563 0.9478779678910418 0.7642417747111299 0.9665231063138237 1.016208165197786 0.8450114917911238 0.9431354886447233 0.8804455392526896 0.9547672810958908 0.6880521395980645 1.0 14.60213373722179 -10.889709550255983 9.269546005985626 1.0000001435300687 0.893797697367529 0.10617641920254473 0.09540641320526207 2.7183696320073005e-07 1.861743110418099e-08 0.08874563695883123 0.021523949502992926 1.2891114021570205e-11 10.889709550255983 -0.10620244616253971 VS(ph)PSPSQESLSSSK ddPTM_PC-9_AZD4547_30min_R2 1 VSPSPSQESLSSSK 14 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83;Q5JSH3-3 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 VS(0.781)PS(0.052)PS(0.14)QES(0.026)LS(0.001)SSK 83.292 0.0082384 17170000.0 20883.0 17107.0 22537.0 13085.0 15246.0 24855.0 25921.0 24958.0 24150.0 22646.0 True False 27523.359606616115 22636.503204381916 22238.144654585787 10068.45541123475 13129.356065116128 23300.812920847584 28227.918784369267 21101.314577784815 25426.519696797834 21853.170432905947 1.2594675766209256 1.0358452689453448 1.0176164013758002 0.46073202248374573 0.6007986852720592 1.0662440487702332 1.2917081698069945 0.9655951131928662 1.1635162858800217 1.0 14.415554979001723 -6.974432859273105 24.66895547156836 1.11328625706826 0.8652307181691863 0.19583963250666403 0.22589838457645434 333.6243238828851 321902.6261328919 0.08759075167659049 0.07724504602767993 1.0606378973864678e-07 6.974432859273105 -0.24805553889907372 VS(ph)PSPSQESLSSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSPSPSQESLSSSK 14 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83;Q5JSH3-3 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 VS(0.997)PS(0.003)PSQESLSSSK;VS(0.846)PS(0.143)PS(0.009)QES(0.001)LSSSK 179.55 5.8178000000000004e-05 39098000.0 77885.0 109683.0 82074.0 62975.0 89281.0 66046.0 68717.0 39790.0 56924.0 50398.0 True False 91069.39220113064 120571.60337030569 84030.95542737836 59446.71491770468 71787.02895902123 62582.43149266187 62207.62829200282 38745.55466098987 57756.40581037231 59534.75844965152 1.5296844158383196 2.0252304117815974 1.4114604243912947 0.9985211406875649 1.2058002892500428 1.0511914908597095 1.0448959551017871 0.650805607849353 0.9701291701589222 1.0 15.86144458917429 -5.582594462313897 3.0933737973185194 0.9860335069485048 1.777790281823504 0.7712016533609611 0.17341876455203475 0.11147336672050798 2.152588132042944 0.050112645741757125 0.1003128542471766 2.6146016907670984e-06 5.582594462313897 0.7917567748749993 VS(ph)PSPSQESLSSSK ddPTM_PC-9_Lapatinib_30min_R1 2 VSPSPSQESLSSSK 14 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83;Q5JSH3-3 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 VS(0.969)PS(0.031)PSQESLSSSK;VS(0.998)PS(0.002)PSQESLSSSK 187.08 4.6169e-06 36413000.0 17824.5 33019.0 30941.0 23576.0 32689.0 28732.0 30761.0 34503.0 30860.0 25295.0 True False 17570.319361387043 32942.54653418131 28397.150415713946 25309.857687230484 30766.297289046717 27503.199337563303 32353.654065271054 36106.13533939417 27384.221829793438 29667.207046531144 0.5922471681890751 1.1104026908401927 0.9571898821205113 0.8531257306268691 1.0370473108840923 0.9270572485784141 1.0905527444671952 1.2170385733569045 0.9230468438381481 1.0 14.856581493432627 -4.753289227414398 24.99959969883625 1.013387333178524 0.5922463957975204 0.6094075570663412 0.10101267296947676 216.09584085866905 662795.961219095 0.02607297181696694 0.2849758656969125 1.76486208273142e-05 4.753289227414398 -0.42114093738100356 VS(ph)PSPTTYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSPSPTTYR 9 0 P11274-2;P11274 P11274-2 BCR Breakpoint cluster region protein 1 VS(0.906)PS(0.089)PT(0.005)TYR 89.171 0.009551700000000002 8792700.0 29539.0 37983.0 44050.0 34924.0 42145.0 38294.0 47634.0 47152.0 40532.0 31589.0 True False 34539.36927815619 41753.70121909805 45100.31906055527 32967.32150513567 33886.98979041391 36285.795227265764 43121.76267970465 45914.30996167368 41124.703820989525 37315.83564161359 0.9255954927521131 1.118927139140239 1.2086107220994575 0.8834673252867322 0.9081128482789241 0.9723966944157308 1.155588825448048 1.2304242735615256 1.1020710943192278 1.0 15.187500373391487 -7.26700892796354 24.72388226426685 1.1412230794831322 1.0077476672292993 0.2190841563923115 0.10757243204109382 609.8162594623834 2707032.3322116984 0.04718932294952852 0.03282080700974191 5.4074320655921815e-08 7.26700892796354 -0.13347541225383286 VS(ph)PSPTTYR ddPTM_PC-9_Lapatinib_30min_R1 1 VSPSPTTYR 9 0 P11274-2;P11274 P11274-2 BCR Breakpoint cluster region protein 1 VS(0.978)PS(0.021)PTTYR 92.23899999999999 0.014312 0.0 68332.0 63094.0 76235.0 56282.0 65131.0 61497.0 55738.0 58487.0 75910.0 60741.0 True False 67357.57314944596 62947.90971948377 69967.25257561 60421.16603124808 61300.12263247276 58866.91666650876 58623.84091187144 61204.519537290835 67360.21643226243 71240.00091770502 0.9455021375877863 0.8836034377961322 0.9821343581457097 0.8481353909729081 0.8604733554577771 0.8263183030347039 0.8229062346530918 0.8591313692990127 0.9455392415010713 1.0 16.120399914573603 -5.779193650467244 24.99935086968446 0.8690142022916021 0.9317323451328063 0.15031959960475272 0.05710968283755499 367.23932837829454 517099.52885498345 0.015626665806448295 0.023232482483926703 1.6626711055318284e-06 5.779193650467244 0.06271814284120425 VS(ph)PSSTEADGELYVFNTPSGTSSVETQMR ddPTM_PC-9_AZD4547_30min_R2 1 VSPSSTEADGELYVFNTPSGTSSVETQMR 29 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 VS(0.782)PS(0.094)S(0.115)T(0.008)EADGELYVFNTPSGTSSVETQMR 94.34899999999999 1.0878000000000001e-10 4159100.0 1566.7 4163.6 5766.2 4835.3 7867.7 10150.0 6844.6 8764.0 8257.9 4365.4 True False 2064.8780106155946 5509.402276364331 5689.736420431847 3720.596289640304 6775.405661387522 9515.318895457784 7453.75614025284 7409.725176685071 8694.395735163022 4212.56867472435 0.49017076516876257 1.3078486552447337 1.3506572497133607 0.8832132071731179 1.608378684017744 2.258792587180889 1.7694088134339028 1.7589565295739489 2.063917862592932 1.0 12.040484490452526 -6.405474201322945 4.704046123467139 1.8283967696890249 1.0579604680600945 0.4710531445203796 0.3799119864904721 0.1955231429907359 6.70565675665254 0.11570510336199658 0.13102168003936523 3.93120597011901e-07 6.405474201322945 -0.7704363016289304 VS(ph)PSSTEADGELYVFNTPSGTSSVETQMR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSPSSTEADGELYVFNTPSGTSSVETQMR 29 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 VS(0.6)PS(0.124)S(0.138)T(0.138)EADGELYVFNTPSGTSSVETQMR;VS(0.474)PS(0.153)S(0.186)T(0.186)EADGELYVFNTPSGTSSVETQMR 105.96 1.6906e-05 2199400.0 4249.0 3730.8999999999996 4682.0 5474.6 7518.1 8476.6 11112.8 9809.0 6920.799999999999 4591.1 True False 4968.271778424651 4101.279095340886 4793.636636583878 5167.875910892674 6044.98227413242 8032.072173798537 10060.115134295278 9551.524143494586 7022.003607132744 5423.430086872396 0.9160755645123052 0.7562149838103707 0.883875436725375 0.9528796035191273 1.114604996709465 1.4809948768843635 1.8549358935493871 1.7611592646163887 1.294753227137518 1.0 12.404989867627158 -6.599010532946884 2.2571392821671847 1.5572891741679875 0.8668887619853843 0.5960617439050993 0.2307014935652384 0.18935525474498385 1.9609664164605627 0.08431666064939035 0.08631652047909794 2.5176158672644654e-07 6.599010532946884 -0.6904004121826032 VS(ph)PSTSYTPSR ddPTM_PC-9_AZD4547_30min_R2 2 VSPSTSYTPSR 11 0 Q9BTE3;Q9BTE3-2 Q9BTE3 MCMBP Mini-chromosome maintenance complex-binding protein 1 VS(0.997)PS(0.001)T(0.001)SYTPSR;VS(0.888)PS(0.097)T(0.006)S(0.006)YT(0.002)PSR 145.14 0.00019553 167846000.0 56418.0 69490.0 117593.0 129355.0 118627.0 89876.0 81648.0 92517.0 70004.0 106850.0 True False 74357.75043269966 91951.2835489858 116033.6399860986 99534.20326482774 102157.6887010711 84256.03951213426 88914.51382686551 78220.62347916182 73704.26852400151 103109.21402260874 0.7211552443450422 0.8917853212305901 1.125346954547204 0.9653279215473691 0.9907716751547637 0.8171533486198378 0.8623333488641398 0.7586191420488415 0.7148174799183359 1.0 16.6538137346963 -6.773438468067608 24.35018316140522 0.8174826017585851 0.948090080645799 0.16932429926169845 0.11727653161799764 263.5544983047695 534836.4855404856 0.04252701631885282 0.03780795099773513 1.6848511238007027e-07 6.773438468067608 0.1306074788872139 VS(ph)PSTSYTPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VSPSTSYTPSR 11 0 Q9BTE3;Q9BTE3-2 Q9BTE3 MCMBP Mini-chromosome maintenance complex-binding protein 1 VS(0.959)PS(0.032)T(0.004)S(0.004)YT(0.001)PSR;VS(0.823)PS(0.121)T(0.028)S(0.028)YTPSR;VS(0.996)PS(0.004)TSYTPSR 128.08 0.0003279 166924000.0 82363.0 110328.0 99254.0 103519.0 120133.0 109746.0 113042.0 128129.0 117297.0 70015.0 True False 96305.42915659925 121280.63470764946 101620.59178289112 97719.16604312605 96593.80103195642 103990.7265632087 102333.84340679308 124765.74951389732 119012.2467208776 82708.16526156483 1.164400502079003 1.4663683364768045 1.2286645636681175 1.1814935772555089 1.1678871212591673 1.2573211633257453 1.2372882784083286 1.5085058303412395 1.4389419272510882 1.0 16.335742144264813 VS(ph)PSTSYTPSR ddPTM_PC-9_Lapatinib_30min_R1 4 VSPSTSYTPSR 11 0 Q9BTE3;Q9BTE3-2 Q9BTE3 MCMBP Mini-chromosome maintenance complex-binding protein 1 VS(0.852)PS(0.142)T(0.003)S(0.003)YTPSR;VS(0.921)PS(0.057)T(0.006)S(0.006)YT(0.009)PSR;VS(0.873)PS(0.056)T(0.019)S(0.019)YT(0.033)PSR;VS(0.995)PS(0.004)TSYTPSR 145.09 0.00019416 229878000.0 105349.0 103879.0 147710.0 121603.0 135073.0 114250.0 118066.0 106473.0 139755.0 101964.5 True False 103846.70394135929 103638.4745578069 135565.85397708876 130546.0902757165 127128.27170373542 109363.79382975792 124178.87977862534 111420.12427879662 124014.32021460727 119588.92796584414 0.86836386702136 0.8666226574704904 1.1335987058585206 1.0916235515799744 1.063043827435635 0.9144976519982969 1.0383810766669983 0.9316926422370755 1.0370050331919278 1.0 16.867724299523033 -5.229990032571061 23.73580240183507 1.0238845029428518 0.8674930832942817 0.5043427826037341 0.06291132584520187 315.8445350812543 238375.5376147872 0.01703392140643754 0.04505385908841914 5.888571699750191e-06 5.229990032571061 -0.15639141964857017 VS(ph)PTASR ddPTM_PC-9_AZD4547_30min_R2 1 VSPTASR 7 0 P21580;A0A087WU80 P21580 TNFAIP3 Tumor necrosis factor alpha-induced protein 3;A20p50;A20p37 1 VS(0.5)PT(0.5)ASR 109.48 0.0037754 0.0 17580.0 22812.0 21331.0 23269.0 19267.0 20616.0 20678.0 28113.0 25813.0 21150.0 True False 23170.07431328407 30185.53288702638 21048.13700257219 17904.69155246629 16592.109622628388 19326.878260961326 22518.30194140611 23768.781822472327 27177.422481716047 20409.544937558985 1.1352567822639188 1.4789909809050656 1.0312888928668873 0.8772704931562144 0.8129583326522141 0.9469529242366759 1.1033220980819838 1.1645914641992559 1.3316035494599572 1.0 14.31695639515644 -5.29156034598573 21.427018898311648 1.025323287468643 1.3071235687969016 0.32105426741207055 0.1588083533113504 126.72989426787865 90151.18533186831 0.045224403391804655 0.09419281972038165 5.110220666846332e-06 5.29156034598573 0.2818002813282585 VS(ph)PTPEPSPPATEK ddPTM_PC-9_AZD4547_30min_R2 1 VSPTPEPSPPATEK 14 0 Q5JTC6;Q5JTC6-2 Q5JTC6 AMER1 APC membrane recruitment protein 1 1 VS(0.676)PT(0.066)PEPS(0.258)PPATEK 85.837 0.028266000000000003 0.0 17792.0 14286.0 17918.0 22615.0 18248.0 18944.0 14748.0 15905.0 17846.0 20863.0 True False 23449.485903410125 18903.67012204361 17680.39561258679 17401.46114826702 15714.580183408061 17759.428685276067 16060.543429338299 13447.247710540403 18789.303126668914 20132.592720202967 1.1647524106459806 0.938958552669367 0.8781976498657619 0.8643427793979427 0.780554218813484 0.8821232780144884 0.7977384558731779 0.6679342247382847 0.9332778638001221 1.0 14.297245357258957 -3.5650576740779214 0.9255696413279549 0.827443897434675 3.775889908332885 0.5458683776038931 0.08590905433628875 11.406614519711146 1.3269090189256967 0.027133835138385215 56.45537546641613 0.00027223397587888934 3.5650576740779214 2.94844601089821 VS(ph)RLSTSTTIENIEITIK ddPTM_PC-9_AZD4547_30min_R2 1 VSRLSTSTTIENIEITIK 18 1 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 VS(0.296)RLS(0.152)T(0.152)S(0.152)T(0.123)T(0.123)IENIEITIK 63.165 0.040343000000000004 0.0 2847.3 2523.4 3574.8 2512.5 3768.2 3636.2 1997.9 3421.4 2949.7 3428.6 True False 3752.6821724808724 3339.0397022234965 3527.395816267174 1933.2819427380443 3245.050473866629 3408.8278391786776 2175.709229554854 2892.7012459505163 3105.6151200680997 3308.565757584618 1.1342323071192264 1.0092106208162916 1.0661404592551638 0.5843262864901967 0.9808027742618126 1.0303037899017775 0.6575989080970259 0.8743067110935407 0.9386590285983374 1.0 11.691990237995984 -5.619909054616357 24.28154364523291 0.8612067856143862 1.0639685986352483 0.30788567398893485 0.13942553055947726 13.340748952914934 3323.2087201664713 0.037391683306839285 0.06476431612148019 2.399335309985714e-06 5.619909054616357 0.20276181302086205 VS(ph)RNYFSK ddPTM_PC-9_Lapatinib_30min_R1 1 VSRNYFSK 8 1 Q9H4Z3;A0A087WWZ2 Q9H4Z3 PCIF1 Phosphorylated CTD-interacting factor 1 1 VS(1)RNYFSK 65.252 0.024671000000000002 39766000.0 74296.0 52863.0 71249.0 59476.0 43765.0 51194.0 46242.0 56870.0 61192.0 45616.0 True False 73236.52541578241 52740.59897139301 65391.18224909351 63850.06344611976 41190.82874530057 49004.55195904272 48636.18449615628 59512.3878141421 54299.91257967338 53500.66482050064 1.368890006535382 0.9857933382387356 1.2222499004168748 1.1934442994370678 0.7699124652656067 0.9159615515705689 0.9090762639928848 1.1123672577492505 1.0149390248112669 1.0 15.707269198675945 -6.226268748097553 24.86405490632886 0.9552087201953758 1.1799411997402203 0.4868923820042086 0.11985134177645983 540.5731868070186 382160.8060917497 0.03580392369803946 0.046220620810103134 5.939245152610043e-07 6.226268748097553 0.22473247954484443 VS(ph)S(ph)S(ph)AT(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSSSATK 7 0 A0A0D9SG79;Q9NZ09-2;Q9NZ09;Q9NZ09-3;Q9NZ09-4 A0A0D9SG79 UBAP1 Ubiquitin-associated protein 1 4 VS(1)S(1)S(1)AT(1)K 51.445 0.037919 0.0 2169.5 3667.8 3663.4 2823.3 4196.0 4857.1 4136.4 5391.9 3705.3 2181.9 True False 2536.7535004218107 4031.9149443542588 3750.749349521868 2665.1196542620987 3373.8239212380317 4602.385125564127 3744.570247057359 5250.368338190281 3759.483002761091 2577.4611980891036 0.9842062810887423 1.564297048329367 1.455210791263366 1.034009612341782 1.3089717601721187 1.7856273176784485 1.4528134312297447 2.0370309908381303 1.4585992625411095 1.0 11.331734993634408 -6.671952692853459 8.101518632696912 1.6051765949644101 1.2807329718786937 0.16451926413394824 0.29832784195599604 0.38756490466754323 30.829117660186576 0.09463735149965301 0.09449089456774205 2.1283708740932834e-07 6.671952692853459 -0.3244436230857164 VS(ph)S(ph)T(ph)TSELTK ddPTM_PC-9_AZD4547_30min_R2 1 VSSTTSELTK 10 0 Q14789-4;Q14789-3;Q14789;Q14789-2;E7EU81 Q14789-4 GOLGB1 Golgin subfamily B member 1 3 VS(0.748)S(0.748)T(0.748)T(0.748)S(0.01)ELTK 94.302 0.016102 0.0 15666.0 6601.9 5244.8 17849.0 12124.0 8685.1 7542.8 4724.1 6003.1 6544.1 True False 20647.46212695725 8735.835067809023 5175.250525108559 13734.188814301035 10440.79187547343 8142.019324033536 8214.09458766022 3994.098894018479 6320.41161042845 6314.9930508690195 3.2695938001255453 1.3833483263464346 0.8195180079250256 2.1748541453123282 1.6533338661452128 1.2893156427009995 1.300728998669264 0.6324787472994673 1.0008580467968504 1.0 12.624565431108435 -4.763410492604775 5.44064128264501 1.2629888641043125 3.367677735451608 0.6817739223643019 0.4145477164318628 0.09481741781733466 8.718410949344365 0.11098232140552605 0.753005068304037 1.7242074107885005e-05 4.763410492604775 2.1046888713472955 VS(ph)SGYVPPPVATPFSSK ddPTM_PC-9_AZD4547_30min_R2 2 VSSGYVPPPVATPFSSK 17 0 Q15942;Q15942-2;H7C3R3 Q15942 ZYX Zyxin 1 VS(0.495)S(0.495)GY(0.009)VPPPVATPFSSK;VS(0.795)S(0.205)GYVPPPVATPFSSK 148.52 7.1247e-05 20687900.0 37931.0 41203.0 72616.0 113774.0 137024.0 120228.0 84065.0 118985.0 99122.0 124324.0 True False 49992.268986187584 54521.063981419786 71653.0643935485 87545.16209077732 118000.58280640648 112710.12415399987 91546.62214451603 100598.60225329433 104361.38655842644 119971.45460128074 0.41670136577350375 0.45445030372114664 0.5972509429987655 0.7297166011842515 0.9835721605491544 0.9394745152385329 0.7630700356911296 0.8385211514491415 0.8698851481401673 1.0 16.872331653569454 -5.707839218598865 1.7722630901385423 0.8855823453835979 0.43206631724246813 0.8742595463838958 0.07062298750483564 0.12523236303288232 0.7961917439705691 0.023214045854923763 0.05149319212427876 1.959569997243738e-06 5.707839218598865 -0.4535160281411298 VS(ph)SGYVPPPVATPFSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSSGYVPPPVATPFSSK 17 0 Q15942;Q15942-2;H7C3R3 Q15942 ZYX Zyxin 1 VS(0.739)S(0.261)GYVPPPVATPFSSK;VS(0.515)S(0.423)GY(0.062)VPPPVATPFSSK 154.51 2.6203000000000003e-05 13953100.0 42276.0 64518.0 137537.0 133596.0 176839.0 135122.0 145017.0 127807.0 127061.0 105347.0 True False 49432.49181093913 70922.92065539242 140816.40369197694 126111.04924407559 142188.667399383 128035.96445131362 131279.9399278397 124452.20167270982 128919.0267492042 124445.57717360658 0.3972217649967489 0.5699111391998455 1.1315500871158515 1.01338313589197 1.1425771058221226 1.0288510637280286 1.0549184865340688 1.0000532320975457 1.035947035460786 1.0 16.925155431930605 -5.153570296112382 3.918854007188579 1.052280966385963 0.4328688314414288 0.9499254749716588 0.052581292450524134 0.04245947106436681 1.1317271240063729 0.013477568896777812 0.04146634521030466 7.021496826373264e-06 5.153570296112382 -0.6194121349445341 down VS(ph)SGYVPPPVATPFSSK ddPTM_PC-9_Lapatinib_30min_R1 2 VSSGYVPPPVATPFSSK 17 0 Q15942;Q15942-2;H7C3R3 Q15942 ZYX Zyxin 1 VS(0.71)S(0.29)GYVPPPVATPFSSK;VS(0.992)S(0.008)GYVPPPVATPFSSK 164.82 2.7731999999999998e-05 15361200.0 208721.0 179433.0 221289.0 175714.0 158699.0 176994.0 132066.0 128364.0 193133.0 118162.0 True False 205744.60026525645 179017.53391283067 203095.47262024262 188636.5937247209 149364.63683423857 169424.37921316564 138903.73127609902 134328.2600558211 171380.32775934853 138586.14425903183 1.4845971894614407 1.291741933293334 1.4654818034379844 1.3611504579573237 1.077774676774762 1.2225203328876366 1.0022916217112843 0.9692762633236097 1.2366339266862132 1.0 17.080423499530824 -6.222035443208977 4.160753611404742 1.0844202928135835 1.4033246269249988 0.7216003058223825 0.09639000021921318 0.119242582268944 4.629726305827666 0.029090961476309244 0.03703893772091795 5.997421287005598e-07 6.222035443208977 0.3189043341114153 VS(ph)SLAGFTDCHR ddPTM_PC-9_AZD4547_30min_R2 1 VSSLAGFTDCHR 12 0 H0YLN8;Q96QT4 H0YLN8 TRPM7 Transient receptor potential cation channel subfamily M member 7 1 VS(0.5)S(0.5)LAGFTDCHR 168.0 0.00053535 3340500.0 14707.0 27541.0 32439.0 32324.0 25837.0 20985.0 31329.0 32888.0 25340.0 24996.0 True False 19383.5200753964 36443.0896563911 32008.837664733946 24872.20120082171 22249.978529083404 19672.80463262872 34117.22030768509 27805.915291056466 26679.42066736468 24120.89764819026 0.8035986205036904 1.5108513036257316 1.3270168520090504 1.0311474126539324 0.9224357589674019 0.8155917296098111 1.4144258147144384 1.152772823657443 1.1060708045152863 1.0 14.557995977023568 -5.77090356050876 24.97505784435372 1.0680232841074628 1.2435251686468967 0.08358606616602193 0.2216977132096667 438.5504109175724 1157292.8159248838 0.06372532572655167 0.09593376959164887 1.6947140871054575e-06 5.77090356050876 0.17550188453943383 VS(ph)SPAPMEGGEEEEELLGPK ddPTM_PC-9_Lapatinib_30min_R1 1 VSSPAPMEGGEEEEELLGPK 20 0 O14497-2;O14497;H0Y488;A0A1B0GTU5;O14497-3 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 VS(0.5)S(0.5)PAPMEGGEEEEELLGPK 61.102 0.0086046 2794100.0 59561.0 70011.0 64567.0 50318.0 68081.0 67923.0 60975.0 66851.0 64076.0 55358.0 True False 58711.64921785029 69848.89383096313 59258.55049582756 54018.553575927326 64076.60943239587 65018.09162624645 64131.98714703362 69957.14151157394 56859.08612980699 64926.556540101614 0.9042778848372667 1.0758139281238681 0.912701268227998 0.8319947407431502 0.9869090992499998 1.0014098250549959 0.987762027814039 1.0774811608615837 0.8757446745953362 1.0 15.986521075834993 -6.487113748895593 24.968351647612945 0.9933753450031751 0.9363614072302499 0.12514969636161377 0.07278686171262001 1313.8064998574366 917198.8900727042 0.022866746769062432 0.02591843731783256 3.2575137016528245e-07 6.487113748895593 -0.057013937772925294 VS(ph)SPLASFLQQQR ddPTM_PC-9_AZD4547_30min_R2 2 VSSPLASFLQQQR 13 0 Q8NEV8-2;Q8NEV8;E9PPH6 Q8NEV8-2 EXPH5 Exophilin-5 1 VS(0.831)S(0.169)PLASFLQQQR;VS(0.652)S(0.348)PLASFLQQQR 211.83 1.2324e-10 31666000.0 70540.0 66177.0 103525.0 131818.0 124904.0 106607.0 92417.0 138147.0 98950.0 102011.0 True False 92970.252676852 87567.4210882319 102152.19085796675 101429.39666779844 107563.23559997801 99940.84743724825 100641.93396454843 116799.55545224933 104180.29498957141 98439.62593973204 0.944439312820748 0.8895545899559141 1.0377141306947637 1.0303716181316742 1.092682286966752 1.015250174746045 1.022372169782164 1.1865095416327347 1.0583166483520976 1.0 16.58695155526589 -5.364075254400056 4.070893619572912 1.0621399776832976 0.9170810009794556 0.5330759948460697 0.051794962101164396 0.16521152590833163 4.740610849498755 0.014142301903891279 0.03196910441067407 4.324388916784496e-06 5.364075254400056 -0.14505897670384205 VS(ph)SPLASFLQQQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSSPLASFLQQQR 13 0 Q8NEV8-2;Q8NEV8;E9PPH6 Q8NEV8-2 EXPH5 Exophilin-5 1 VS(0.494)S(0.494)PLAS(0.012)FLQQQR;VS(0.495)S(0.495)PLAS(0.011)FLQQQR 139.19 6.7352e-05 20833200.0 62930.0 51126.0 79148.0 80510.0 104887.0 90984.0 84900.0 81544.0 79779.0 58126.0 True False 73582.80607584452 56201.45140003701 81035.18849046159 75999.28571694189 84335.14528762942 86212.63887182192 76857.65737722877 79403.5564030097 80945.61694796017 68663.78367483716 1.071639256355312 0.8185021039065292 1.1801736541960781 1.1068321850255527 1.228233295255112 1.2555765828473533 1.1193332680470152 1.15641102417297 1.178869159487112 1.0 16.067261737842614 -5.2806067767154365 24.90606549115695 1.1622383641023355 0.9450706778122598 0.47138513340868204 0.08773298720851976 512.9948558197524 666583.5673261352 0.02159852884521564 0.04507304913956637 5.240747348569605e-06 5.2806067767154365 -0.21716768629007566 VS(ph)SPLASFLQQQR ddPTM_PC-9_Lapatinib_30min_R1 1 VSSPLASFLQQQR 13 0 Q8NEV8-2;Q8NEV8;E9PPH6 Q8NEV8-2 EXPH5 Exophilin-5 1 VS(0.905)S(0.095)PLASFLQQQR 140.45 7.2869e-05 11735000.0 39277.0 43218.0 48276.0 33632.0 49403.0 45789.0 34161.0 38797.0 47128.0 29608.0 True False 38716.90277748033 43117.931376306005 44306.93363074904 36105.40947306307 46497.21267003506 43830.71120937236 35929.68942894328 40599.650255411834 41819.948360158945 34725.70334981987 1.1149350205366297 1.241671937986237 1.2759117701493254 1.039731553003961 1.338985482932666 1.262197939314013 1.0346713230541278 1.1691527122264158 1.2042937745241054 1.0 15.083716295038213 -10.955601072466479 0.31906500424443435 0.8657267677049973 1.2057234870855278 0.2595640805354157 0.09495388014184111 29.886161563309265 1.9468296158192082 3.370447772400254 0.09194012028477613 1.1076407564080764e-11 10.955601072466479 0.33999671938053044 VS(ph)SPSPATDGK ddPTM_PC-9_AZD4547_30min_R2 1 VSSPSPATDGK 11 0 A0A0A0MQS0;F8W9L8;A8MW92-4;A8MW92 A0A0A0MQS0 PHF20L1 PHD finger protein 20-like protein 1 1 VS(0.78)S(0.219)PS(0.001)PATDGK 108.98 0.0021171999999999996 8403400.0 73605.0 100460.0 88541.0 98974.0 90260.0 114650.0 86373.0 106490.0 111270.0 81881.0 True False 97009.85892089177 132931.7303976272 87366.88848833823 76157.07343305684 77728.95700100907 107480.91737578665 94060.02967332758 90034.41739675873 117151.50503779265 79014.37111263664 1.2277495543513495 1.6823740862042706 1.1057088382541815 0.9638382532272938 0.9837318946727401 1.3602704908271732 1.1904167349410784 1.1394688855830135 1.4826607285248241 1.0 16.269827453691725 -5.28536063795591 24.853993554576405 1.15414333083749 1.4550618736564915 0.29596770856675647 0.1861846160330688 775.0723951953634 805292.6743603664 0.04878113188508952 0.10162832787622701 5.183694064171582e-06 5.28536063795591 0.30091854281900154 VS(ph)SPSPELGTTPASIFR ddPTM_PC-9_AZD4547_30min_R2 2 VSSPSPELGTTPASIFR 17 0 A0A5E8;Q99501 A0A5E8 GAS2L1 GAS2-like protein 1 1 VS(0.419)S(0.419)PS(0.094)PELGT(0.001)T(0.013)PAS(0.054)IFR;VS(0.484)S(0.484)PS(0.031)PELGTTPASIFR 203.05 3.9093e-17 25573000.0 20165.4 21290.7 31981.0 37561.0 36317.0 32642.0 30813.0 34342.0 24876.0 26638.0 True False 26577.57773362335 28172.502412669317 31556.911043985816 28901.89176166515 31275.01142705119 30600.890579855466 33555.297307309535 29035.233000652548 26190.894574639467 25705.41172797617 1.0339292758613148 1.095975536622435 1.227636864094312 1.124350470146725 1.2166703166638415 1.1904454557540256 1.3053787141168425 1.1295377529025301 1.0188864061700644 1.0 14.649784499715974 -8.209740515197714 3.8207224365100654 1.0047601490897309 1.1730753246379162 0.43993147101609775 0.0713664663184574 0.21418115503924057 6.187165943891832 0.06131940567001409 0.019480509775127535 6.1696351872347084e-09 8.209740515197714 0.16831517554818531 VS(ph)SPSPELGTTPASIFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSSPSPELGTTPASIFR 17 0 A0A5E8;Q99501 A0A5E8 GAS2L1 GAS2-like protein 1 1 VS(0.901)S(0.098)PSPELGTTPASIFR 190.18 1.2117e-08 9034300.0 11446.0 14730.0 15582.0 13980.0 20118.0 20163.0 15110.0 15009.0 18217.0 13458.0 True False 13383.581731195232 16192.297052821374 15953.53397506408 13196.74592377153 16176.022318271369 19105.616785067105 13678.671413073373 14615.029653350022 18483.38916182194 15897.828866530608 0.8418496540349247 1.0185225409559353 1.003503944406569 0.8300973695568195 1.0174988329586587 1.2017752200924612 0.860411288101787 0.919309786012275 1.1626360628862134 1.0 13.956542132646225 -6.47840846063003 24.924800898432306 1.0239662853200864 0.9344714190015195 0.17298336416854232 0.10973866296767398 944.3336884342723 529282.4933559616 0.03477817997394828 0.03943295840350599 3.323468289592905e-07 6.47840846063003 -0.08949486631856685 VS(ph)SPTVNTTLR ddPTM_PC-9_AZD4547_30min_R2 1 VSSPTVNTTLR 11 0 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 VS(0.598)S(0.383)PT(0.017)VNT(0.001)TLR 121.68 0.0007440000000000001 22440000.0 30213.0 41687.0 46024.0 68790.0 52982.0 47544.0 33933.0 56467.0 37333.0 45406.0 True False 39820.10553056041 55161.50751628394 45413.69168845261 52931.528294905525 45626.363835890275 44571.06616410291 36952.97126306866 47741.32263257374 39306.34616316993 43816.349760510755 0.9087955922436985 1.2589252143956078 1.036455385641947 1.208031444522788 1.041309102316204 1.017224538504856 0.843360331589564 1.08957781498267 0.8970703031632854 1.0 15.419181681272384 -6.70349791351801 2.769403506476448 0.9635140302832538 1.1098186650270283 0.2533102928544779 0.10795501715990706 0.3414098295738394 5.339360593245685 0.03679962687912059 0.03533459208172581 1.9792565301614903e-07 6.70349791351801 0.14630463474377453 VS(ph)SPTVNTTLR ddPTM_PC-9_Lapatinib_30min_R1 1 VSSPTVNTTLR 11 0 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 VS(0.615)S(0.382)PT(0.003)VNTTLR 130.44 0.00020925 19105000.0 104210.0 89916.0 97233.0 74461.0 84879.0 97486.0 74287.0 87550.0 78414.0 63122.0 True False 102723.94629022645 89707.80502642273 89238.87807023394 79937.11033461422 79886.58409853456 93316.75103096527 78133.21737091732 91617.89261698852 69582.18958397348 74032.55359522201 1.3875510339934587 1.2117345771551555 1.2054005128359282 1.079756221454629 1.0790737347156747 1.260482672814191 1.0553900085375412 1.2375352215717905 0.9398863905791877 1.0 16.175872171685235 -1.5228787452839243 0.5841649899103948 1.0980369885576364 17.028079235752283 0.48751049318999484 0.09294273840144304 140.05454660746173 1.1463427515442557 0.04116926518340634 2833.6960778371244 0.029999999999752235 1.5228787452839243 15.930042247194647 VS(ph)SPVFGATSSIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSSPVFGATSSIK 13 0 F6Q6H0;I6L8A6;Q99708-3;Q99708;Q99708-2 F6Q6H0 RBBP8 DNA endonuclease RBBP8 1 VS(0.639)S(0.361)PVFGAT(0.001)SSIK 185.2 4.7305e-05 8614300.0 63005.0 60246.0 55964.0 66282.0 83663.0 69253.0 70187.0 60228.0 65342.0 49856.0 True False 73670.50209452692 66226.8247280568 57298.3940046519 62568.43442914329 67269.8357298708 65621.2507670611 63538.379250124526 58647.0788168409 66297.50313508094 58894.49814012114 1.2508893771240035 1.1244993474685985 0.9728989262855792 1.0623816554184937 1.1422091681607194 1.1142169954642578 1.0788508478152699 0.995798939950357 1.1256994325233345 1.0 15.845845244900467 -4.850178166773879 3.6542217218419806 1.0658523540580858 1.2586313398289029 0.521399169498004 0.054967283097260136 0.2000038312478301 4.477043706854648 0.014174990522239767 0.0923634223865551 1.4119581781966532e-05 4.850178166773879 0.1927789857708171 VS(ph)SPVFGATSSIK ddPTM_PC-9_Lapatinib_30min_R1 1 VSSPVFGATSSIK 13 0 F6Q6H0;I6L8A6;Q99708-3;Q99708;Q99708-2 F6Q6H0 RBBP8 DNA endonuclease RBBP8 1 VS(0.746)S(0.254)PVFGATSSIK 92.906 0.0043855 37354000.0 232630.0 226710.0 268590.0 247650.0 262130.0 215800.0 245340.0 231350.0 242220.0 205320.0 True False 229312.65354088304 226185.06692402114 246507.56698738248 265863.00713618175 246712.02876740886 206570.73705437005 258042.50474216012 242099.3655846985 214938.63291032298 240809.28842829663 0.9522583411858848 0.9392705256523775 1.0236630347453668 1.1040396691979975 1.0245120957652338 0.8578188092436416 1.0715637524878732 1.0053572566275242 0.8925678669339331 1.0 17.877531514835923 VS(ph)T(ph)QLKT(ph)NLTSVT(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 VSTQLKTNLTSVTK 14 1 P42858 P42858 HTT Huntingtin 4 VS(1)T(1)QLKT(0.996)NLT(0.124)S(0.097)VT(0.783)K 66.67399999999999 0.037192 0.0 2115.0 841.57 2548.0 4978.4 4342.3 2656.2 870.42 2684.4 2443.8 2743.7 True False 2787.5260052671097 1113.5910447016836 2514.211855166375 3830.706795513264 3739.4465985539664 2490.107394099995 947.8856937730295 2269.587661375332 2572.97427888342 2647.6438981172837 1.0528326740802625 0.42059698643520316 0.9496034783809895 1.446836108978721 1.4123676530718705 0.9404993609112949 0.35801102045749533 0.8572103155523354 0.9717977106789322 1.0 11.370493380762074 -7.008052279771301 24.8845665286398 0.76548412504265 1.0508307108974952 0.13102123020203116 0.31096394646106934 773.1972002405245 2389472.1866133553 0.12468069574204868 0.10509147759146548 9.816297686683652e-08 7.008052279771301 0.2853465858548453 VS(ph)VELTNSLFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSVELTNSLFK 11 0 P14923 P14923 JUP Junction plakoglobin 1 VS(0.998)VELT(0.002)NSLFK 90.73100000000001 0.023478 0.0 11751.0 13806.0 11128.0 14819.0 16242.0 10525.0 13948.0 13420.0 11031.0 10588.0 True False 13740.212207170642 15176.568439324628 11393.333723175012 13988.739473846232 13059.496694172567 9973.050471796423 12626.744465224838 13067.739219665355 11192.30750639829 12507.520585438124 1.0985560338127829 1.2133954396200588 0.9109186465333262 1.1184262602879596 1.044131537099134 0.7973643060326076 1.0095321753797888 1.0447905426499529 0.8948462191162756 1.0 13.610508206334197 -5.3661246534233715 0.8464909864842391 0.9640559443617448 1.1819574916303752 0.2878656830097879 0.09681960922956696 1.5395268508425992 1.4982771684439289 0.03937118758955334 0.2673867692217899 4.304030562744922e-06 5.3661246534233715 0.21790154726863042 VS(ph)VSPGR ddPTM_PC-9_Lapatinib_30min_R1 1 VSVSPGR 7 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 VS(0.626)VS(0.374)PGR 91.265 0.015373 358390000.0 778330.0 708190.0 732850.0 612310.0 684350.0 605490.0 651100.0 648870.0 833360.0 554620.0 True False 767230.8714717578 706550.229566063 672597.9018828082 657341.3200062801 644097.8784838669 579594.6041661293 684810.7721432317 679018.8690163937 739498.2211301572 650485.3280153043 1.179474522219672 1.0861893406909244 1.033993962530979 1.0105398103472896 0.9901804863901756 0.891018719721981 1.0527689751783607 1.0438650032094468 1.1368407391853712 1.0 19.311156991121194 -4.826992354911933 1.5988988386139205 1.0150385030107867 1.2306440698661427 0.42613386759141003 0.05782276560459246 0.9648173778857506 2.5597717709971852 0.0174942889927865 0.3193316303300985 1.4893872958585003e-05 4.826992354911933 0.21560556685535603 VS(ph)WQEPR ddPTM_PC-9_AZD4547_30min_R2 1 VSWQEPR 7 0 P16144-4;P16144-2;P16144-3;P16144 P16144-4 ITGB4 Integrin beta-4 1 VS(1)WQEPR 77.533 0.029654000000000003 4615500.0 15429.0 35422.0 27156.0 23299.0 22388.0 21776.0 28854.0 34694.0 24597.0 23642.0 True False 20335.101056863485 46871.46878503631 26795.893696584808 17927.77551596167 19279.812645009835 20414.343277585074 31421.950102395374 29332.83948880784 25897.14720422926 22814.300776064738 0.8913313301364788 2.054477550949568 1.1745218036529657 0.785813060498015 0.8450757634105072 0.894804687549419 1.3772918315936824 1.2857216084212375 1.1351278068271478 1.0 14.477650817581873 -5.505446385416264 24.833088204674855 1.051335862260796 1.5083032965954608 0.22183540660597756 0.3142210609557133 883.3378644043577 1258347.710436195 0.08204677667849353 0.16492458740772403 3.122867907157387e-06 5.505446385416264 0.4569674343346648 VS(ph)Y(ph)VSGSS(ph)LLT(ph)THPQPMDQAS(ph)LK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSYVSGSSLLTTHPQPMDQASLK 23 0 H0YBH8;G3XAN1;Q9NV88-3;Q9NV88-2;Q9NV88 H0YBH8 INTS9 Integrator complex subunit 9 5 VS(0.843)Y(0.825)VS(0.374)GS(0.491)S(0.806)LLT(0.531)T(0.154)HPQPMDQAS(0.978)LK 50.358000000000004 0.029036000000000003 0.0 7285.9 9576.9 8021.9 9850.6 10917.0 12935.0 9903.9 9822.5 8454.9 9414.2 True False 8519.258966915542 10527.63134047284 8213.172519225167 9298.702818076095 8777.89221834023 12256.665829233902 8965.730893973347 9564.669782799017 8578.536917400681 11120.9199372338 0.7660570361982669 0.9466511223793116 0.7385335534811968 0.8361451094475768 0.7893134981532498 1.10212697316501 0.8062040680605302 0.8600610234388683 0.7713873461743932 1.0 13.440988514192723 VS(ph)YVS(ph)GS(ph)SLLTT(ph)HPQPMDQAS(ph)LK ddPTM_PC-9_Lapatinib_30min_R1 1 VSYVSGSSLLTTHPQPMDQASLK 23 0 H0YBH8;G3XAN1;Q9NV88-3;Q9NV88-2;Q9NV88 H0YBH8 INTS9 Integrator complex subunit 9 5 VS(0.662)Y(0.638)VS(0.661)GS(0.519)S(0.519)LLT(0.487)T(0.524)HPQPMDQAS(0.991)LK 46.027 0.028664 4090300.0 11776.0 9995.9 12431.0 10740.0 14188.0 7819.2 10094.0 10438.0 12314.0 11075.0 True False 11608.072080546079 9972.755107696272 11408.971165047662 11529.855427589717 13353.489734681232 7484.791043445464 10616.617929678676 10922.987585792433 10927.067647831376 12989.298993490112 0.8936642451885766 0.7677669990269951 0.8783361727808046 0.8876426228519468 1.028037751796586 0.5762274813441927 0.8173357111110799 0.8409220229103003 0.8412361323969622 1.0 13.665035953067736 -9.082922676840147 2.304159345794899 0.9999983574200225 0.8343523588506938 0.16978503781939092 0.10825830953977932 20.32067699889576 81.15930306870773 0.10521201644437567 0.028560626327241555 8.261850330732707e-10 9.082922676840147 -0.1656459985693287 VSAEAEVAPVS(ph)PEVTQEVVEEHCAS(ph)PEDK ddPTM_PC-9_AZD4547_30min_R2 5 VSAEAEVAPVSPEVTQEVVEEHCASPEDK 29 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 VSAEAEVAPVS(0.997)PEVT(0.113)QEVVEEHCAS(0.89)PEDK;VSAEAEVAPVS(0.844)PEVT(0.205)QEVVEEHCAS(0.951)PEDK;VSAEAEVAPVS(0.987)PEVT(0.016)QEVVEEHCAS(0.997)PEDK;VSAEAEVAPVS(0.997)PEVT(0.009)QEVVEEHCAS(0.994)PEDK;VSAEAEVAPVS(0.996)PEVT(0.005)QEVVEEHCAS(0.999)PEDK 103.96 7.5296e-11 47926200.0 73629.3 93933.5 77270.9 74991.7 76687.0 90615.5 95033.5 97197.2 87952.6 78755.0 True False 97041.88581542029 124295.66690529064 76246.23737809088 57703.52217521536 66040.33376397478 84949.29846023211 103491.29739571613 82177.60610945859 92601.59487720845 75997.81142115632 1.2769036897344876 1.6355163994984352 1.0032688567248056 0.759278735744643 0.8689767840550001 1.1177861160957572 1.361766812233571 1.0813154296517271 1.2184771264535383 1.0 16.213670252088463 -5.273262867449938 24.78010977077168 1.0507761809508096 1.456210046844051 0.45240722291074587 0.17816292886228105 560.0034644032547 1173677.2737056136 0.0512791572371119 0.10814314956132387 5.330121790597614e-06 5.273262867449938 0.4054338658932415 VSAEAEVAPVS(ph)PEVTQEVVEEHCAS(ph)PEDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSAEAEVAPVSPEVTQEVVEEHCASPEDK 29 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 VSAEAEVAPVS(0.998)PEVT(0.008)QEVVEEHCAS(0.994)PEDK;VSAEAEVAPVS(0.962)PEVT(0.093)QEVVEEHCAS(0.945)PEDK 95.36 3.2060000000000006e-10 29831000.0 57029.0 74868.0 51178.0 56935.0 58021.0 42619.0 65832.0 42998.0 45749.0 44078.0 True False 66682.88332590718 82300.40025462527 52398.27761364582 53745.1165357605 46652.20155723352 40383.98461353841 59595.91637759408 41869.34806014684 46417.99257639523 52068.992478743996 1.280663983523956 1.5806028950574103 1.0063240158725224 1.0321904453538397 0.8959689699446027 0.7755860578639824 1.1445567417484175 0.8041128907427788 0.8914709189993322 1.0 15.668136870779582 -5.365050356507141 5.050857289878874 0.9338928135296722 1.4276414567169902 0.716884695392397 0.12275485125238696 0.10305444542679658 3.9821989368082242 0.031622730676721056 0.06834757284972404 4.314690450298916e-06 5.365050356507141 0.4937486431873179 VSAEAEVAPVS(ph)PEVTQEVVEEHCAS(ph)PEDK ddPTM_PC-9_Lapatinib_30min_R1 4 VSAEAEVAPVSPEVTQEVVEEHCASPEDK 29 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 VSAEAEVAPVS(0.961)PEVT(0.039)QEVVEEHCAS(1)PEDK;VSAEAEVAPVS(0.963)PEVT(0.037)QEVVEEHCAS(1)PEDK;VSAEAEVAPVS(0.999)PEVT(0.002)QEVVEEHCAS(1)PEDK;VSAEAEVAPVS(0.999)PEVT(0.025)QEVVEEHCAS(0.976)PEDK 105.72 6.1848e-11 52648200.0 66619.0 137915.0 108923.0 115657.0 136966.0 124419.0 139281.0 141377.0 110235.0 123670.0 True False 65669.00084357164 137595.66629097261 99967.77139493915 124162.80160044153 128909.92916551662 119097.88940485471 146492.28867283292 147945.89154211312 97819.17347398835 145046.1947200833 0.45274542341702 0.9486334099044167 0.6892133336407857 0.856022468152691 0.8887508521977624 0.8211031639588698 1.0099698854943444 1.019991540127101 0.674400136196363 1.0 17.146152921434442 -4.755346269931745 24.996690571322304 0.8752908082452749 0.45274472988578746 0.5409299069700774 0.1176770810581352 158.050411730284 648331.3189504502 0.028829829213666378 0.2580263561674935 1.756522551983188e-05 4.755346269931745 -0.4225460783594875 VSAEAEVAPVS(ph)PEVTQEVVEEHCASPEDK ddPTM_PC-9_AZD4547_30min_R2 4 VSAEAEVAPVSPEVTQEVVEEHCASPEDK 29 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 VSAEAEVAPVS(0.993)PEVT(0.007)QEVVEEHCASPEDK;VSAEAEVAPVS(0.959)PEVT(0.041)QEVVEEHCASPEDK;VSAEAEVAPVS(0.946)PEVT(0.054)QEVVEEHCASPEDK;VSAEAEVAPVS(0.883)PEVT(0.117)QEVVEEHCASPEDK 136.71 4.5345e-12 256991100.0 109450.0 120534.0 131622.0 148208.0 141464.0 140726.0 127084.0 153982.0 134620.0 143540.0 True False 144252.8232985743 159494.25832916162 129876.60627971296 114040.93539077404 121824.16544638522 131926.3809736146 138394.2298056704 130187.62005434986 141735.73836782287 138514.70829017568 1.0414260339514112 1.1514608108984044 0.9376376551119273 0.8233128221435422 0.8795034617636035 0.9524359008665049 0.999130211614402 0.9398830034830573 1.023254065343728 1.0 17.07967965252101 -5.2743402857438015 24.265605601599024 0.9378477304776801 1.0964434168867994 0.4928813421372473 0.06140506429713511 374.50327116530406 704412.838376595 0.01708960092428619 0.0359658287442265 5.316914961169262e-06 5.2743402857438015 0.15859568640911925 VSAEAEVAPVS(ph)PEVTQEVVEEHCASPEDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 VSAEAEVAPVSPEVTQEVVEEHCASPEDK 29 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 VSAEAEVAPVS(0.89)PEVT(0.11)QEVVEEHCASPEDK;VSAEAEVAPVS(0.995)PEVT(0.005)QEVVEEHCASPEDK;VSAEAEVAPVS(0.958)PEVT(0.042)QEVVEEHCASPEDK;VSAEAEVAPVS(0.591)PEVT(0.409)QEVVEEHCASPEDK;VSAEAEVAPVS(0.595)PEVT(0.405)QEVVEEHCASPEDK 131.5 6.5871e-12 263528000.0 155175.7 208933.0 162946.0 192517.5 211464.0 165361.5 186148.0 167841.6 154745.1 138409.3 True False 181443.88115022116 229674.48744990627 166831.25061614602 181731.36862515623 170029.14720702564 156689.65183771643 168514.7138451872 163435.93584287493 157007.95433853296 163501.81044258384 1.1097362204067946 1.40472137175851 1.0203633229781963 1.1114945341169418 1.0399221069587727 0.9583358827255335 1.0306596201536478 0.999597101710797 0.9602826654550636 1.0 17.31894708509642 -5.288223294320156 23.8574086221503 1.0179276324100903 1.2572287539800249 0.6079951391726793 0.07774716169545634 224.02225316317794 199544.5031652826 0.01939076734873593 0.040388374617544374 5.1496380571396445e-06 5.288223294320156 0.23930112156993455 VSAEAEVAPVS(ph)PEVTQEVVEEHCASPEDK ddPTM_PC-9_Lapatinib_30min_R1 4 VSAEAEVAPVSPEVTQEVVEEHCASPEDK 29 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 VSAEAEVAPVS(0.647)PEVT(0.353)QEVVEEHCASPEDK;VSAEAEVAPVS(0.831)PEVT(0.169)QEVVEEHCASPEDK;VSAEAEVAPVS(0.961)PEVT(0.039)QEVVEEHCASPEDK;VSAEAEVAPVS(0.511)PEVT(0.465)QEVVEEHCAS(0.024)PEDK 151.42 2.0427e-13 181477000.0 92597.5 142422.0 147037.8 145902.3 147029.7 146213.4 136750.0 148331.6 140741.7 136041.8 True False 91277.04266969816 142092.23060938128 134948.91966632192 156632.44185780516 138381.70211751215 139960.19372208268 143830.245877111 155223.6276471285 124889.88767019579 159556.44386569588 0.5720674167602354 0.8905452338169756 0.8457754284114846 0.9816741841504567 0.8672899618770192 0.8771829600306958 0.9014380265216857 0.9728446177816895 0.7827317070021934 1.0 17.283707349085724 -4.760056369288594 5.888499753501774 0.9009566899081909 0.558823583130257 0.7093593978493486 0.06341759773461396 0.07135576866096671 9.091132863666353 0.014668859841155813 0.09871788380840547 1.737575285383021e-05 4.760056369288594 -0.34213310677793385 VSAEAEVAPVSPEVT(ph)QEVVEEHCASPEDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSAEAEVAPVSPEVTQEVVEEHCASPEDK 29 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 VSAEAEVAPVS(0.017)PEVT(0.982)QEVVEEHCAS(0.001)PEDK;VSAEAEVAPVS(0.002)PEVT(0.989)QEVVEEHCAS(0.009)PEDK 114.34 7.9865e-13 4439200.0 24287.7 30619.3 21261.1 26176.3 30051.4 20267.7 28646.0 17463.7 16044.9 20204.2 True False 28399.127906058897 33658.98174809595 21768.04525717076 24709.72677570962 24163.043895779916 19204.826132753282 25932.443500919915 17005.296379319658 16279.526308531409 23867.061523640805 1.189887907982681 1.410269199446947 0.9120538460760691 1.0353066191761453 1.0124012908688376 0.8046581735137572 1.0865369193117178 0.7125006303132696 0.6820917728982351 1.0 14.542733334480655 -5.316511765803951 0.5815013192515828 0.83342173988082 1.4539465919778884 0.493606487974391 0.1493542349060781 1.8223868057062025 0.7171452493637247 0.08663820760771844 0.7028591243470159 4.824899083795343e-06 5.316511765803951 0.6205248520970684 VSAEAEVAPVSPEVT(ph)QEVVEEHCASPEDK ddPTM_PC-9_Lapatinib_30min_R1 1 VSAEAEVAPVSPEVTQEVVEEHCASPEDK 29 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 VSAEAEVAPVS(0.033)PEVT(0.967)QEVVEEHCASPEDK 113.68 1.0078e-12 9436800.0 8982.4 9586.3 11983.0 12988.0 14936.0 14021.0 11823.0 12950.0 14736.0 11034.0 True False 8854.309328829579 9564.10351133052 10997.80399571766 13943.180846697893 14057.49384530582 13421.354514547365 12435.137089616703 13551.704276299282 13076.276503040706 12941.212198119174 0.6841947410549709 0.7390423219179213 0.8498279625857645 1.0774246363663167 1.0862578891449506 1.0371018038401358 0.9608943041227604 1.0471742576223915 1.0104367583850578 1.0 13.659685139871087 -5.517690414061628 2.7213558995545557 1.0327787594202233 0.7109073487069946 0.9178694540320362 0.038798924518665144 0.07307602428664826 1.0795736311450623 0.01182773598895862 0.026479394009613286 3.0360546583785747e-06 5.517690414061628 -0.3218714107132288 VSAEAEVAPVSPEVTQEVVEEHCAS(ph)PEDK ddPTM_PC-9_AZD4547_30min_R2 2 VSAEAEVAPVSPEVTQEVVEEHCASPEDK 29 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 VSAEAEVAPVS(0.001)PEVT(0.488)QEVVEEHCAS(0.511)PEDK;VSAEAEVAPVSPEVT(0.137)QEVVEEHCAS(0.863)PEDK 115.76 1.87e-13 107449000.0 69102.0 81386.0 70656.0 65871.0 62553.0 82300.0 79177.0 82512.0 76432.0 68969.0 True False 91074.99858910998 107692.4329100268 69719.05527418977 50685.45864680507 53868.59569337592 77153.76798977081 86223.59961382675 69761.66633713346 80472.03948097932 66554.41630252973 1.3684290787724664 1.6181109968796077 1.0475496465520013 0.7615641675288574 0.8093917531860073 1.1592584275558917 1.295535358944308 1.0481898905104186 1.2091164486393458 1.0 16.022246780718376 -5.272468693168733 23.95124063550827 1.0380627024657894 1.4932700268487908 0.5458861078299986 0.16486166510513445 290.22532632226677 630254.5700402294 0.04783724981319828 0.10126130816819287 5.339877655721953e-06 5.272468693168733 0.4552073243830015 VSAEAEVAPVSPEVTQEVVEEHCAS(ph)PEDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VSAEAEVAPVSPEVTQEVVEEHCASPEDK 29 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 VSAEAEVAPVSPEVT(0.001)QEVVEEHCAS(0.999)PEDK;VSAEAEVAPVSPEVTQEVVEEHCAS(1)PEDK;VSAEAEVAPVS(0.009)PEVT(0.405)QEVVEEHCAS(0.586)PEDK 144.26 2.2246e-13 64719100.0 149018.0 204584.0 131767.0 152869.0 157639.0 122408.0 160875.0 110419.0 117780.0 117394.0 True False 174243.8041603397 224893.7474714466 134908.82500913052 144304.24553798462 126750.7695710301 115988.7089930316 145635.75536586234 107520.61824860117 119502.30968213163 138676.60290960752 1.2564758618576464 1.6217137047843415 0.9728304716049836 1.0405810534026805 0.9140025563912109 0.8363971034727149 1.0501825997337917 0.7753335169212754 0.8617337544677661 1.0 17.0813648755545 -5.336451729852613 6.429237327675239 0.9250203771288057 1.4370301452109946 0.7503627027069701 0.11718856855967856 0.09620815477786167 6.709512208146101 0.029881354965234065 0.06331816397051653 4.608379861988536e-06 5.336451729852613 0.5120097680821889 VSAEAEVAPVSPEVTQEVVEEHCAS(ph)PEDK ddPTM_PC-9_Lapatinib_30min_R1 3 VSAEAEVAPVSPEVTQEVVEEHCASPEDK 29 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 VSAEAEVAPVS(0.001)PEVT(0.043)QEVVEEHCAS(0.956)PEDK;VSAEAEVAPVS(0.005)PEVT(0.059)QEVVEEHCAS(0.936)PEDK;VSAEAEVAPVSPEVT(0.003)QEVVEEHCAS(0.997)PEDK 102.76 2.6974e-11 75894000.0 53606.0 113243.0 93277.0 95349.0 107858.0 92396.0 115686.0 118160.0 95509.0 112448.0 True False 52841.56860986357 112980.79279112896 85608.12511963265 102361.28353493987 101514.00449698669 88444.43846559593 121675.6550240548 123650.1449642878 84751.77066564298 131884.48697245846 0.4006655355978184 0.8566647631174608 0.649114441621252 0.776143471341827 0.7697190687649711 0.6706204838486111 0.9225926249344581 0.937563983473733 0.6426212256741141 1.0 17.00891535074637 -3.1858749984791035 0.17698904768966336 0.9611828158103394 3.6639501974674695e-30 0.38369834608356934 0.1333154690758524 37.959830643793474 0.709146856012911 0.3353012346746221 8.743885422065471 0.0006518159770655311 3.1858749984791035 -0.9611828158103394 VSAGEPGS(ph)HPSPAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSAGEPGSHPSPAPR 15 0 C9JME2;Q9Y4F1;Q9Y4F1-2;A0A1B0GV68 C9JME2 FARP1 FERM, RhoGEF and pleckstrin domain-containing protein 1 1 VS(0.003)AGEPGS(0.896)HPS(0.102)PAPR 70.41199999999999 0.02377 8395800.0 45221.0 57426.0 82997.0 77938.0 130500.0 108940.0 84757.0 98787.0 90786.0 105280.0 True False 52876.022144537776 63126.87376478749 84975.96324787514 73571.38653840541 104929.46180208819 103226.99462209051 76728.20337245928 96193.94592347837 92113.5734997623 124366.43060397834 0.42516313998679905 0.5075877265128178 0.6832709022458417 0.5915694949280947 0.843712095719917 0.8300229742123707 0.6169526857033141 0.7734719526508727 0.7406626776407274 1.0 16.9242375954614 -4.384655593028862 0.4483385206899962 0.8097428993118925 5.401565026329339e-78 0.634509756979613 0.09861652891627623 5.020411172592452 0.60105976765595 0.06936492169966466 2.324279105739218 4.1242445290833384e-05 4.384655593028862 -0.8097428993118925 VSAGEPGSHPS(ph)PAPR ddPTM_PC-9_AZD4547_30min_R2 5 VSAGEPGSHPSPAPR 15 0 C9JME2;Q9Y4F1;Q9Y4F1-2;A0A1B0GV68 C9JME2 FARP1 FERM, RhoGEF and pleckstrin domain-containing protein 1 1 VSAGEPGSHPS(1)PAPR;VSAGEPGS(0.007)HPS(0.993)PAPR;VSAGEPGSHPS(1)PAPR;VSAGEPGS(0.152)HPS(0.848)PAPR;VSAGEPGS(0.002)HPS(0.998)PAPR 137.85 2.5874e-05 61470600.0 121886.0 140033.0 211151.0 256655.0 232190.0 244033.0 215918.0 302234.0 240594.0 290081.0 True False 160643.21261370563 185295.92875543403 208350.99977638753 197487.15503022185 199954.42639113963 228773.57793253715 235134.28371140934 255530.6799463986 253311.3076576139 279925.3524837841 0.5738787544190432 0.6619476482258537 0.7443091450191429 0.7054993528735921 0.7143133861114737 0.8172663744195513 0.8399892386490092 0.9128529362527152 0.9049244929406246 1.0 18.094682630323213 -6.4055012593657015 0.2681917406548682 1.0291979809879421 0.48493024307385396 0.9359204218058284 0.03137729957456476 0.9243049499789475 0.11831218191079348 0.053804379547254116 0.16517306605115373 3.9309610500703016e-07 6.4055012593657015 -0.5442677379140881 VSAGEPGSHPS(ph)PAPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VSAGEPGSHPSPAPR 15 0 C9JME2;Q9Y4F1;Q9Y4F1-2;A0A1B0GV68 C9JME2 FARP1 FERM, RhoGEF and pleckstrin domain-containing protein 1 1 VSAGEPGS(0.004)HPS(0.996)PAPR;VSAGEPGS(0.007)HPS(0.993)PAPR;VSAGEPGS(0.003)HPS(0.997)PAPR 106.31 0.00054214 41268000.0 58094.0 72655.0 108681.0 98432.0 162496.0 89657.0 106305.0 89395.0 83699.0 76633.0 True False 67928.16679119834 79867.70823983292 111272.36721498755 92917.17416084971 130656.07528729594 84955.22908787186 96235.0208184489 87048.47597183191 84922.93953204907 90525.95627350578 0.7503722643477765 0.882263071582794 1.2291763798528756 1.0264147211007564 1.443299586833915 0.9384626529787423 1.0630654983383367 0.961585820853774 0.9381059646083347 1.0 16.466043891281366 -5.04564927395078 5.26340387777676 1.0795194813585123 0.7765201224089922 0.34355795429895053 0.14797472245457394 0.1916606024687446 12.809023357471693 0.03840080075075891 0.1167294504849338 9.002242881001465e-06 5.04564927395078 -0.3029993589495201 VSAGEPGSHPS(ph)PAPR ddPTM_PC-9_Lapatinib_30min_R1 6 VSAGEPGSHPSPAPR 15 0 C9JME2;Q9Y4F1;Q9Y4F1-2;A0A1B0GV68 C9JME2 FARP1 FERM, RhoGEF and pleckstrin domain-containing protein 1 1 VSAGEPGS(0.006)HPS(0.994)PAPR;VSAGEPGS(0.001)HPS(0.999)PAPR;VSAGEPGSHPS(1)PAPR;VSAGEPGS(0.026)HPS(0.974)PAPR;VSAGEPGS(0.001)HPS(0.999)PAPR;VSAGEPGS(0.232)HPS(0.768)PAPR 169.15 1.1487000000000001e-20 50966900.0 338829.0 348040.0 370501.0 320375.0 362042.0 322337.0 312464.0 336157.0 428242.0 261776.0 True False 333997.2363263712 347234.13476351433 340039.8379552195 343936.4462396707 340747.4013619584 308551.3979142468 328641.85702190624 351776.08142146276 380008.8763718209 307023.63280540577 1.0878551376468846 1.130968751788545 1.1075363640516223 1.1202279221862395 1.109840953441936 1.0049760505238023 1.0704122481353162 1.1457622275104193 1.237718650188319 1.0 18.22799018416555 -7.774653859057965 24.455141671164956 1.1438053676074076 1.0911154749435796 0.05145740656392028 0.0635758453317127 401.7509310005164 743478.7421897064 0.03387446707588505 0.016436142370968913 1.680142590140084e-08 7.774653859057965 -0.05268989266382795 VSAS(ph)SPSLAVASQSDSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSASSPSLAVASQSDSK 17 0 A0A494C0P1;P04150-7;P04150-5;P04150-2;P04150-6;P04150-10;P04150;P04150-3;D6RDA9;Q3MSN4;P04150-9;P04150-8 A0A494C0P1 NR3C1 Glucocorticoid receptor 1 VSAS(0.5)S(0.5)PSLAVASQSDSK;VSAS(0.941)S(0.057)PS(0.002)LAVASQSDSK 310.98 1.3163999999999998e-129 15925300.0 108254.0 101567.0 108723.0 115589.0 125323.0 103886.0 113743.0 81488.0 97718.0 72777.0 True False 126579.26408603933 111649.90052708128 111315.36865427335 109112.92307459436 100766.85778868316 98438.0352791489 102968.43961199246 79349.02634367289 99146.94088570659 85970.89399758494 1.47235021296388 1.2986941898058861 1.2948029673554444 1.2691844646591617 1.1721043379113154 1.1450158385222118 1.1977127935285286 0.9229754705807983 1.153261717721486 1.0 16.391560688286056 -1.800222846532579 0.19756399582473316 0.9684702087190337 3.032039958254207 0.7779435728726909 0.06987494407077105 20.789699242718346 0.2743136325171869 0.127861464813458 12.933836062988886 0.01584080155758579 1.800222846532579 2.0635697495351732 VSAS(ph)SPTTK ddPTM_PC-9_AZD4547_30min_R2 2 VSASSPTTK 9 0 Q5JWZ0;Q5JXL1;Q9BVI0 Q5JWZ0 PHF20 PHD finger protein 20 1 VS(0.031)AS(0.484)S(0.484)PTTK;VSAS(0.546)S(0.432)PT(0.013)T(0.009)K 146.71 0.00042235 38010000.0 229055.0 211540.0 251283.0 273499.0 249103.0 255287.0 227003.0 282412.0 253249.0 258719.0 True False 301889.72536002676 279916.1681098352 247950.82323460476 210448.03106742783 214519.3482807701 239323.86353347098 247205.8272369194 238771.71458215304 266635.2251219198 249661.3265579351 1.209196993071219 1.121183532784279 0.9931487053004446 0.8429340417631417 0.8592414020959304 0.9585940555271973 0.9901646788676904 0.9563824636922488 1.0679876967650648 1.0 17.92961283433248 -5.180069722371697 2.602855570367126 0.9481044369363869 1.197141523389056 0.6487756067914671 0.06252704190961665 0.19124960663015225 2.4197782077180903 0.01831217593974886 0.06899783917325128 6.605873876762049e-06 5.180069722371697 0.2490370864526692 VSAS(ph)SPTTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSASSPTTK 9 0 Q5JWZ0;Q5JXL1;Q9BVI0 Q5JWZ0 PHF20 PHD finger protein 20 1 VSAS(0.753)S(0.218)PT(0.018)T(0.011)K 124.67 0.0014513 14304000.0 119470.0 128940.0 123550.0 127060.0 139400.0 98224.0 120920.0 115080.0 114170.0 96755.0 True False 139693.91135994202 141740.3110652269 126495.90056598446 119941.24013407812 112085.57069127315 93072.9605265304 109465.58221501201 112059.27193733888 115839.5202615804 114295.91558784137 1.2222126279970276 1.2401170272466415 1.1067403407671805 1.0493921809646651 0.9806612083625205 0.8143157176513433 0.9577383553210435 0.9804311148040672 1.0135053353901584 1.0 16.80241432360205 -5.684237558202487 1.4606815805867868 0.9504054085139401 1.2395690546610771 0.7981957376602123 0.05404566334112278 0.19171509600208794 0.8100660415161569 0.018904287130693736 0.04877310660630128 2.0690092953074128e-06 5.684237558202487 0.2891636461471371 VSAS(ph)SPTTK ddPTM_PC-9_Lapatinib_30min_R1 3 VSASSPTTK 9 0 Q5JWZ0;Q5JXL1;Q9BVI0 Q5JWZ0 PHF20 PHD finger protein 20 1 VS(0.001)AS(0.603)S(0.38)PT(0.015)T(0.002)K;VSAS(0.95)S(0.049)PT(0.001)TK;VSAS(0.5)S(0.5)PTTK 125.68 0.0014187000000000002 42310100.0 162561.0 230589.0 254112.0 223680.0 234170.0 236913.0 207517.0 204037.0 234914.0 193163.0 True False 160242.8503299636 230055.08533784564 233219.89226068655 240130.17337460644 220396.5809959335 226780.78326117666 218261.21487152102 213517.30389368974 208455.5115659136 226550.96717648092 0.7073147924596412 1.0154672399108986 1.0294367539777953 1.0599388577650497 0.9728344298978286 1.0010144122868243 0.9634088858314065 0.9424691783697481 0.9201263369735643 1.0 17.789476124359993 -4.758314182256493 24.999872642205233 0.9900997240320313 0.7073144054065369 0.8224443818375565 0.03932049248735279 38.79516002746498 310287.3103363224 0.010930393235254438 0.07564166635836292 1.7445596271211395e-05 4.758314182256493 -0.2827853186254944 VSASS(ph)PTTK ddPTM_PC-9_AZD4547_30min_R2 2 VSASSPTTK 9 0 Q5JWZ0;Q5JXL1;Q9BVI0 Q5JWZ0 PHF20 PHD finger protein 20 1 VSAS(0.079)S(0.916)PT(0.004)TK;VS(0.001)AS(0.205)S(0.783)PT(0.009)T(0.001)K 107.11 0.0025241 11786200.0 100021.0 99625.0 98921.0 134394.0 124474.0 118679.0 106979.0 136332.0 112875.0 108027.0 True False 131825.59743395832 131826.83297694213 97609.24290616676 103411.53966660169 107192.93367763763 111257.98336887025 116499.92375421626 115265.02199769835 118841.3420611203 104245.0076108597 1.2645746828093225 1.2645865351081724 0.9363445323975241 0.9920047207692737 1.0282788225003767 1.0672739723343834 1.117558782182677 1.105712634488701 1.1400195058237017 1.0 16.669618767770835 -5.239642816019142 24.545129469248717 1.0525859978453442 1.2645807027808555 0.6780215111363428 0.059533652734483876 405.23991081252825 456338.75649696897 0.01677235667887738 0.0442879491408287 5.759134005776145e-06 5.239642816019142 0.2119947049355113 VSASS(ph)PTTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSASSPTTK 9 0 Q5JWZ0;Q5JXL1;Q9BVI0 Q5JWZ0 PHF20 PHD finger protein 20 1 VSAS(0.327)S(0.671)PT(0.002)T(0.001)K;VSAS(0.068)S(0.924)PT(0.007)T(0.001)K 140.17 0.00078992 20473500.0 178739.0 198095.0 163165.0 179951.0 197585.0 166704.0 194152.0 158657.0 128912.0 129655.0 True False 208995.98244383215 217760.56243575327 167055.47240670805 169868.92887901317 158869.63762579017 157961.74877438004 175760.51702124596 154492.4218609866 130797.09412245656 153160.42515158444 1.3645560348698869 1.4217808694395657 1.0907221773599254 1.1090915209388597 1.037276029160635 1.0313483304714235 1.1475582993929012 1.0086967420473263 0.8539875362255318 1.0 17.224684044459586 -5.334629896746796 3.5377576207368344 1.036136777160544 1.3981557965244238 0.7868708938393771 0.07487512348312128 0.10474846471513746 2.530508698748302 0.021020414494383008 0.05117572261021417 4.627752277858144e-06 5.334629896746796 0.3620190193638797 VSASS(ph)PTTK ddPTM_PC-9_Lapatinib_30min_R1 1 VSASSPTTK 9 0 Q5JWZ0;Q5JXL1;Q9BVI0 Q5JWZ0 PHF20 PHD finger protein 20 1 VSAS(0.426)S(0.568)PT(0.005)TK 97.59700000000001 0.004732500000000001 9091100.0 28463.0 35591.0 43223.0 39226.0 49590.0 41514.0 38902.0 37437.0 42884.0 34497.0 True False 28057.11240052508 35508.591226204524 39669.371785604984 42110.81089410005 46673.21369769117 39738.54299386061 40916.155211052115 39176.459690487754 38053.952331460205 40459.760485636856 0.6934572044855605 0.8776273215658311 0.9804648200942154 1.0408072215120827 1.1535711812792386 0.9821744497960566 1.0112802132275913 0.9682820466620243 0.9405382502194815 1.0 15.304200158980823 -4.850983530331758 1.718754852962908 1.0161548410813313 0.6110537743909915 0.7684433167764545 0.05426837139700958 0.40080817207420183 1.333858519731425 0.01656903309023336 0.2586819454511864 1.409342243630238e-05 4.850983530331758 -0.40510106669033974 VSASSPS(ph)LAVASQSDSK ddPTM_PC-9_AZD4547_30min_R2 1 VSASSPSLAVASQSDSK 17 0 A0A494C0P1;P04150-7;P04150-5;P04150-2;P04150-6;P04150-10;P04150;P04150-3;D6RDA9;Q3MSN4;P04150-9;P04150-8 A0A494C0P1 NR3C1 Glucocorticoid receptor 1 VS(0.009)AS(0.171)S(0.148)PS(0.667)LAVAS(0.004)QSDS(0.002)K 78.486 0.0070033000000000005 12810000.0 38100.0 38942.0 33561.0 46850.0 42602.0 47103.0 37306.0 50098.0 32506.0 38550.0 True False 50215.00747076923 51529.23994768463 33115.95921163217 36049.45632528453 36687.44766404809 44157.64196381753 40626.16172870181 42356.50523751354 34224.20079768576 37200.376233706775 1.3498521400778218 1.3851806127969928 0.8902049539387786 0.9690616056893692 0.9862117370416829 1.1870213808162204 1.0920900765484993 1.1386042165652848 0.9199960931221888 1.0 15.183029591951524 -5.247666727297345 24.77832602851562 1.0329485441510706 1.3675164499215031 0.7041189838598901 0.08916771832427606 405.908456891295 730264.9297176433 0.024199309090097605 0.06329466001178799 5.6537066747936276e-06 5.247666727297345 0.3345679057704325 VSDEVGFGLEHVS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 VSDEVGFGLEHVSR 14 0 Q6VY07-2;Q6VY07 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 VSDEVGFGLEHVS(1)R 81.643 0.017555 0.0 8528.7 7040.5 11745.0 21109.0 19215.0 19781.0 13029.0 20745.0 13918.0 14992.0 True False 11240.64919201967 9316.203940518557 11589.253625953324 16242.646180798953 16547.32892504305 18544.090942960614 14188.55575948256 17539.33692267593 14653.677065839856 14467.13464320965 0.7769782662039179 0.6439563998176547 0.8010745674087508 1.1227272422201906 1.1437875801349349 1.2818081396418426 0.9807440180383028 1.2123573434016708 1.0128942203989069 1.0 13.820491589920952 -5.6931745129879125 3.877955029208968 1.1215805965943064 0.7131841614714347 0.7592624838980258 0.09524255129600416 0.0938447207920033 2.7784071544187343 0.025361156496769295 0.04501443015680878 2.0268680974184574e-06 5.6931745129879125 -0.4083964351228717 VSDQNS(ph)PVLPK ddPTM_PC-9_AZD4547_30min_R2 2 VSDQNSPVLPK 11 0 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 VSDQNS(1)PVLPK;VS(0.028)DQNS(0.972)PVLPK 162.67 0.0014513 515300000.0 1831720.0 1533080.0 1991790.0 2415400.0 2055070.0 1891880.0 1934110.0 1913700.0 1747390.0 2064370.0 True False 2414168.8578571468 2028618.1289866036 1965377.5631875335 1858566.8475580006 1769759.0035903356 1773580.444525976 2106242.0431324607 1617981.637451186 1839753.4680326125 1992097.0346453292 1.2118731245875092 1.0183329896617093 0.9865872640774485 0.932970038725497 0.8883899593301797 0.8903082599295884 1.0572989199331115 0.8122002138009556 0.9235260311303862 1.0 20.925856491826593 -3.837625484222614 0.9364868725943114 0.9231008352362994 2.476365342938399 0.640484519527381 0.06318034561951785 6.153475583126487 1.1401913134175612 0.020365095222729376 14.759069063537023 0.0001453364392587812 3.837625484222614 1.5532645077020995 VSDQNS(ph)PVLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSDQNSPVLPK 11 0 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 VSDQNS(1)PVLPK;VS(0.006)DQNS(0.994)PVLPK 106.55 0.00242 312920000.0 591070.0 642520.0 576660.0 698390.0 735700.0 493350.0 678930.0 614600.0 539110.0 465950.0 True False 691126.4768353634 706305.1393332516 590409.7613952284 659261.4725109288 591544.8662666385 467477.85750696156 614616.8353724624 598467.4012225287 546993.4638540833 550423.0465418285 1.2556277960698405 1.2832041531887002 1.0726472394363327 1.1977359535595484 1.0747094802500878 0.849306475163075 1.1166262736161712 1.0872862337115985 0.9937691877015462 1.0 19.070181352244838 -5.562433436045943 0.9129428815299311 1.0216970585306324 1.2991716848498982 0.5477172481951951 0.08313629455764353 0.7033271642322091 0.9565124728903323 0.034380512822317244 0.15412927746325958 2.738839381730629e-06 5.562433436045943 0.2774746263192658 VSDQNS(ph)PVLPK ddPTM_PC-9_Lapatinib_30min_R1 4 VSDQNSPVLPK 11 0 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 VSDQNS(1)PVLPK;VSDQNS(1)PVLPK;VSDQNS(1)PVLPK;VSDQNS(1)PVLPK 127.78 0.0003432 499969000.0 2496030.0 2862688.0 2946816.0 2831524.0 3146223.0 2901507.0 2824611.0 2799820.0 3106770.0 2061399.0 True False 2460436.1544841537 2856059.621819025 2704540.1635187054 3039763.720647164 2961168.348852409 2777416.3093531686 2970855.5366522353 2929909.8584454255 2756852.8468615445 2417709.070508489 1.0176725498104198 1.1813082296201762 1.1186375550760086 1.2572909444426437 1.2247827437027485 1.1487801999142215 1.2287895069307944 1.2118537727242804 1.1402748496458788 1.0 21.205209220947268 -4.760914320244657 24.54260221201206 1.1789152658534905 1.0176723295649175 0.2785176579266643 0.07061866873163661 11.71911651636185 547121.009944063 0.01640709791355713 0.09447632498247212 1.7341460848932107e-05 4.760914320244657 -0.161242936288573 VSDQNS(ph)PVLPKK ddPTM_PC-9_AZD4547_30min_R2 2 VSDQNSPVLPKK 12 1 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 VS(0.048)DQNS(0.952)PVLPKK;VS(0.003)DQNS(0.997)PVLPKK 69.594 0.014565999999999999 68351000.0 308680.0 180485.0 346830.0 694380.0 500520.0 330050.0 277760.0 333570.0 259600.0 368870.0 True False 406833.8190571408 238823.24667345965 342230.8075853036 534301.4190640576 431031.43760408816 309411.9213247132 302480.10190758045 282024.4211760425 273321.9260160959 355955.9735752891 1.1429329727798214 0.6709347908244769 0.9614413944170472 1.501032315028831 1.2109122183699486 0.8692421094016807 0.8497682982235503 0.7923014139735762 0.767853179343498 1.0 18.441339286885594 -6.86336224057742 7.003231922525994 0.8391685409728467 1.0880284440987975 0.2598734172456828 0.2030322161595729 0.35480588564531657 21.389824516974894 0.07963944173955292 0.07030542106602874 1.3697388044628237e-07 6.86336224057742 0.24885990312595085 VSDQNS(ph)PVLPKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VSDQNSPVLPKK 12 1 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 VS(0.004)DQNS(0.996)PVLPKK;VS(0.006)DQNS(0.994)PVLPKK;VS(0.001)DQNS(0.999)PVLPKK;VSDQNS(1)PVLPKK 90.70700000000001 0.0031181 57009700.0 287510.0 136535.0 208349.0 339093.0 319091.0 411692.0 316292.0 440446.0 373412.0 273130.0 True False 336179.7644186561 150089.2924716202 213316.8303279824 320094.7185643389 256567.40916390988 390102.1467776547 286330.5320042224 428884.7591911127 378872.4440739 322646.3069041104 1.0419451802948043 0.4651821181893345 0.661147596496059 0.9920916858951377 0.7951971049219572 1.2090705470048724 0.8874440087402551 1.3292721782759351 1.1742655532285384 1.0 18.2995939865403 -6.4739777614901985 1.0778481245056815 1.1449821582673874 0.7131283466043725 0.4037146513543678 0.19228086592401036 0.45708215860692186 1.1278884334611434 0.08923600688143805 0.10808853078472071 3.357548064839328e-07 6.4739777614901985 -0.43185381166301484 VSDQNS(ph)PVLPKK ddPTM_PC-9_Lapatinib_30min_R1 2 VSDQNSPVLPKK 12 1 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 VS(0.001)DQNS(0.999)PVLPKK;VS(0.008)DQNS(0.992)PVLPKK 61.443999999999996 0.025580000000000002 50272000.0 639680.0 239327.0 333858.0 266774.0 214587.0 247373.0 150144.0 145585.0 300766.0 157110.0 True False 630558.0458970546 238772.85303570703 306409.4839691478 286393.44989197556 201965.4145542743 236793.4334446281 157917.72165976584 152349.41058417244 266890.5658736114 184266.25416408447 3.4219941614244704 1.2958034780643328 1.6628627165574106 1.5542371075549697 1.096052098472839 1.285061307176568 0.8570083674634428 0.8267895349330167 1.4483963278265377 1.0 17.491432359795866 -2.9395099944230973 1.23070989346525 1.1666459430217944 199.99999999999278 0.8421634709285457 0.2827011261388887 51.850877735596605 1.1466961886030635 0.08603001245833541 28109.991695358778 0.0011494497908163457 2.9395099944230973 198.833354056971 up VSDSPS(ph)HIATK ddPTM_PC-9_AZD4547_30min_R2 1 VSDSPSHIATK 11 0 Q9P2D3 Q9P2D3 HEATR5B HEAT repeat-containing protein 5B 1 VS(0.206)DS(0.046)PS(0.748)HIATK 67.01899999999999 0.023094 8872000.0 36958.0 52372.0 65775.0 93426.0 95164.0 79965.0 60349.0 85905.0 55366.0 70408.0 True False 48709.875225844895 69300.22480972057 64902.78052337845 71888.07911731121 81952.12125021082 74964.77590889484 65719.94408849582 72630.35615051718 58292.53372807077 67943.03735052739 0.7169222502453638 1.019975372195848 0.9552528567207875 1.0580639594669696 1.2061886610604213 1.1033474338531752 0.9672800429783213 1.0689889499023613 0.8579618457051257 1.0 16.052038093977856 -4.315096686176971 1.672507617030107 1.0396184663038306 8.972983969734327e-17 0.508911993189127 0.08998730295852633 3.5111177476537856 3.318632831486962 0.025629906747787503 8.685458355152235 4.8406458918342195e-05 4.315096686176971 -1.0396184663038306 VSDSPS(ph)HIATK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSDSPSHIATK 11 0 Q9P2D3 Q9P2D3 HEATR5B HEAT repeat-containing protein 5B 1 VS(0.329)DS(0.254)PS(0.416)HIATK 57.434 0.043267 6325200.0 60694.0 59512.0 91516.0 97223.0 108880.0 106350.0 105500.0 86936.0 96497.0 83092.0 True False 70968.29543885752 65419.95805889382 93698.08851636262 91775.91051121886 87545.74560161964 100772.81878152497 95506.27624614433 84654.02211630609 97908.08607061148 98155.92184408985 0.7230159332779028 0.6664901804172997 0.9545841631969183 0.9350012590885248 0.8919048790624845 1.02666061189453 0.9730057489332717 0.8624443693857811 0.9974750807814526 1.0 16.58278768908888 -5.26472807950143 24.985303288278953 0.9504373353508324 0.6947530429408703 0.8185325445972621 0.049000196085743866 99.09850762857809 752889.1894820291 0.012598819032520957 0.028080558879661554 5.435905779434242e-06 5.26472807950143 -0.25568429240996216 VSDYS(ph)DDDTQEHK ddPTM_PC-9_AZD4547_30min_R2 1 VSDYSDDDTQEHK 13 0 A6NLU5 A6NLU5 VSTM2B V-set and transmembrane domain-containing protein 2B 1 VSDYS(0.5)DDDT(0.5)QEHK 95.094 0.013944 0.0 20963.0 21705.0 50505.0 76319.0 61021.0 34938.0 34185.0 57647.0 31230.0 39807.0 True False 27628.797942512727 28720.71678559124 49835.27070061925 58724.83366679588 52549.28744913099 32753.32133689693 37227.398774879985 48738.98074627621 32880.75404269139 38413.369046307824 0.7192495380763361 0.7476750282165575 1.2973418353527433 1.5287603020709357 1.3679947568718103 0.852654222997529 0.9691261063303732 1.2688025538067418 0.8559716280822234 1.0 15.229320880602732 -5.247144966544408 23.136602107732784 1.1574747085320847 0.7334619796399315 0.3671132746975778 0.21415544153661992 331.1850824046097 536040.8077109564 0.05913338693295724 0.1544653659700553 5.660503111489138e-06 5.247144966544408 -0.42401272889215313 VSEEAESQQQWDTSKGEQVSQNGLPAEQGS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSEEAESQQQWDTSKGEQVSQNGLPAEQGSPR 32 1 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 VSEEAESQQQWDTSKGEQVSQNGLPAEQGS(1)PR 79.494 1.6004000000000002e-07 5284400.0 8949.1 8634.8 14017.0 9238.0 15987.0 14408.0 11228.0 12852.0 13252.0 10789.0 True False 10464.005877218175 9492.005878594837 14351.218439768518 8720.424810000099 12854.462113639758 13652.419116165604 10164.402556319515 12514.648617819608 13445.785429679105 12744.960294322993 0.821030873032941 0.7447654335041652 1.1260308473586225 0.6842253415167131 1.0085917740650427 1.0712013847737778 0.7975232814846085 0.9819291962324925 1.0549884126095144 1.0 13.637639258341299 -2.4621712055928886 0.2948260996702592 0.998005300204841 4.0144373764205376e-11 0.1788324649217744 0.1319090149121992 56.70591741448961 1.3287541453688891 0.13775477740419748 26.649081739113544 0.0034500770515786088 2.4621712055928886 -0.9980053001646967 VSEEAESQQQWDTSKGEQVSQNGLPAEQGS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 VSEEAESQQQWDTSKGEQVSQNGLPAEQGSPR 32 1 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 1 VSEEAESQQQWDTSKGEQVS(0.002)QNGLPAEQGS(0.998)PR 100.68 1.6026e-13 17196000.0 45454.0 29658.0 50849.0 38035.0 38829.0 45108.0 32027.0 27921.0 53599.0 35572.0 True False 44805.817624757256 29589.328723182094 46668.39150281624 40832.22078104052 36545.154560751165 43178.83599188379 33685.20135068548 29218.311590621786 47562.11619750802 41720.57280328941 1.0739502028415246 0.7092263297221355 1.118594217842012 0.9787070990986287 0.8759504509456256 1.0349530960533553 0.8074002605263753 0.7003334237136385 1.1400158962764297 1.0 15.348471345048358 -7.260581852330565 24.99715434581917 0.8869651849519307 0.9571191918390543 0.016627106756079812 0.1524009806354949 288.45622674068943 8408749.16846506 0.05862045312874467 0.04279869471476297 5.4880511148626595e-08 7.260581852330565 0.07015400688712359 VSEEIEDIIK ddPTM_PC-9_Lapatinib_30min_R1 1 VSEEIEDIIK 10 0 M0QZK8;O75223-3;O75223 M0QZK8 GGCT Gamma-glutamylcyclotransferase 0 97.565 0.02348 1704500.0 12427.0 13090.0 15717.0 11311.0 15205.0 12755.0 14044.0 14311.0 13685.0 13990.0 False True 12249.7887011673 13059.6909092472 14424.808929374489 12142.848672389886 14310.671794180165 12209.498383357231 14771.129602180245 14975.941304874057 12143.651190561342 16408.152859496764 0.7465671977865154 0.7959269407761806 0.8791244848152211 0.7400497043371831 0.8721683614677802 0.7441116917856222 0.9002311063692316 0.9127134195490039 0.7400986140577549 1.0 14.002125216790109 -14.52287874527348 0.16862387563173253 1.687324086958411 0.7763588958257736 0.4071787960837564 0.06731721179365882 132.03523360725353 1.2373212431400118 30.452831574835052 0.23943927791656924 3.000000000047366e-15 14.52287874527348 -0.9109651911326374 VSEEQTQPPS(ph)PAGAGMSTAMGR ddPTM_PC-9_AZD4547_30min_R2 10 VSEEQTQPPSPAGAGMSTAMGR 22 0 H3BM18;X6RHM1;Q16666-3;Q16666-2;Q16666 H3BM18 IFI16 Gamma-interferon-inducible protein 16 1 VS(0.001)EEQT(0.012)QPPS(0.976)PAGAGMS(0.005)T(0.005)AMGR;VSEEQTQPPS(0.894)PAGAGMS(0.078)T(0.028)AMGR;VSEEQT(0.011)QPPS(0.884)PAGAGMS(0.083)T(0.022)AMGR;VSEEQT(0.004)QPPS(0.993)PAGAGMS(0.002)T(0.002)AMGR;VSEEQTQPPS(0.99)PAGAGMS(0.009)T(0.002)AMGR;VSEEQT(0.014)QPPS(0.977)PAGAGMS(0.008)TAMGR;VSEEQT(0.024)QPPS(0.974)PAGAGMST(0.001)AMGR;VSEEQT(0.001)QPPS(0.999)PAGAGMSTAMGR;VSEEQTQPPS(0.992)PAGAGMS(0.008)TAMGR;VSEEQTQPPS(0.759)PAGAGMS(0.12)T(0.12)AMGR 133.84 2.3025e-07 131836200.0 229281.9 240606.2 301369.4 417910.0 343901.0 327389.8 237733.7 354847.4 257570.90000000002 288969.5 True False 302188.77484021493 318377.4488393144 297373.0448447323 321567.30614513654 296156.2823133612 306918.0640512457 258891.53874879846 300013.8879120539 271185.571932586 278852.7657604707 1.0836857723684528 1.1417403301382159 1.0664159777427855 1.153179547164172 1.062052519026309 1.1006455798070962 0.928416607390516 1.0758863628046644 0.9725045085818849 1.0 18.08914405464659 -7.225093348927853 21.894797548127187 1.000525791715886 1.1021159068027053 0.5893318363143838 0.04366165570745284 91.84670281105076 55328.102719014256 0.015532398377990496 0.01203027627296056 5.955341233738124e-08 7.225093348927853 0.10159011508681925 VSEEQTQPPS(ph)PAGAGMSTAMGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VSEEQTQPPSPAGAGMSTAMGR 22 0 H3BM18;X6RHM1;Q16666-3;Q16666-2;Q16666 H3BM18 IFI16 Gamma-interferon-inducible protein 16 1 VSEEQT(0.001)QPPS(0.742)PAGAGMS(0.129)T(0.129)AMGR;VSEEQT(0.001)QPPS(0.514)PAGAGMS(0.243)T(0.243)AMGR;VS(0.001)EEQT(0.039)QPPS(0.694)PAGAGMS(0.133)T(0.133)AMGR 77.045 0.00045196 100357000.0 62033.0 59140.0 56880.0 67487.0 74613.0 57992.0 70567.0 51770.0 56378.1 52810.0 True False 72533.96169240214 65011.028357356125 58236.23491860125 63705.922185806 59993.118263902164 54950.797430918625 63882.38289916275 50411.092354849134 57202.523055613616 62384.03495627004 1.162700709296008 1.0421100270754777 0.9335118345490747 1.0211895115547203 0.9616742217132338 0.8808471184885369 1.0240181313046361 0.8080768162909997 0.9169416998389321 1.0 15.9288892477976 -1.5228787452833055 0.5840212897628452 0.9239190525677522 14.356803678984909 0.5503330717414445 0.06250874712506105 114.98134982533969 0.9415361912935394 0.02855057138056534 1961.142999764777 0.029999999999794986 1.5228787452833055 13.432884626417156 VSEEQTQPPS(ph)PAGAGMSTAMGR ddPTM_PC-9_Lapatinib_30min_R1 15 VSEEQTQPPSPAGAGMSTAMGR 22 0 H3BM18;X6RHM1;Q16666-3;Q16666-2;Q16666 H3BM18 IFI16 Gamma-interferon-inducible protein 16 1 VSEEQT(0.001)QPPS(0.717)PAGAGMS(0.141)T(0.141)AMGR;VSEEQT(0.016)QPPS(0.968)PAGAGMS(0.013)T(0.003)AMGR;VSEEQT(0.002)QPPS(0.971)PAGAGMS(0.013)T(0.013)AMGR;VSEEQTQPPS(0.845)PAGAGMS(0.122)T(0.033)AMGR;VSEEQT(0.006)QPPS(0.865)PAGAGMS(0.096)T(0.033)AMGR;VSEEQTQPPS(0.998)PAGAGMS(0.002)TAMGR;VSEEQT(0.001)QPPS(0.997)PAGAGMS(0.001)TAMGR;VSEEQTQPPS(0.604)PAGAGMS(0.198)T(0.198)AMGR;VS(0.005)EEQT(0.015)QPPS(0.571)PAGAGMS(0.178)T(0.231)AMGR;VSEEQTQPPS(0.987)PAGAGMS(0.013)TAMGR;VSEEQTQPPS(0.775)PAGAGMS(0.223)T(0.002)AMGR;VSEEQTQPPS(0.681)PAGAGMS(0.121)T(0.198)AMGR;VSEEQT(0.001)QPPS(0.999)PAGAGMSTAMGR;VSEEQT(0.02)QPPS(0.98)PAGAGMSTAMGR;VSEEQTQPPS(1)PAGAGMSTAMGR 235.85 1.9605e-51 154873000.0 449875.0 384296.0 456213.0 327355.6 398859.0 421900.0 380493.0 403529.0 419319.0 302093.7 True False 443459.70000303 383406.1862230758 418704.92817310785 351430.42285026924 375398.89780696516 403856.3204969359 400193.0657734525 422278.43049504 372090.87859517644 354310.1935304477 1.2516142862960593 1.0821201117662105 1.1817467739243195 0.9918721766046762 1.0595204559778075 1.1398382769425752 1.129499159439402 1.1918325755387882 1.050183950079327 1.0 18.434653446933048 -14.363720891659511 0.32141716337379955 8.597892084409307e-18 1.122828014248416 0.20654953686194533 0.0724091376332025 512.272297769594 5.006078030423395 347.2728471584533 0.06445789325107437 4.327918843421371e-15 14.363720891659511 1.122828014248416 VSEEQTQPPSPAGAGMST(ph)AMGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSEEQTQPPSPAGAGMSTAMGR 22 0 H3BM18;X6RHM1;Q16666-3;Q16666-2;Q16666 H3BM18 IFI16 Gamma-interferon-inducible protein 16 1 VSEEQT(0.002)QPPS(0.38)PAGAGMS(0.177)T(0.441)AMGR 63.302 0.0037023000000000004 31125000.0 14124.0 16459.0 14887.0 16487.0 14216.0 12407.0 18777.0 13144.0 11067.0 11272.0 True False 16514.914238284244 18092.94074625845 15241.962539261893 15563.28684157519 11430.476850409877 11756.355078724779 16998.30662629244 12798.98392721917 11228.833938292993 13315.52437089709 1.240275168913352 1.3587854478944186 1.1446761024729375 1.168807656992532 0.8584323479886948 0.8829059037599682 1.2765780868115548 0.9612076528651856 0.8432889029015751 1.0 13.700821623148434 -5.824140776188558 1.9210768137754508 0.9823537057411577 1.2857496157271597 0.5021271459789154 0.1258625398963192 0.2937559295822205 2.2140030659848002 0.040947197526549635 0.07721337926345234 1.4991987927122815e-06 5.824140776188558 0.3033959099860021 VSEFNVS(ph)SEGSGEK ddPTM_PC-9_Lapatinib_30min_R1 1 VSEFNVSSEGSGEK 14 0 Q9BVJ6-3;Q9BVJ6 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 1 VSEFNVS(0.796)S(0.202)EGS(0.001)GEK 129.32 2.2946e-05 4940700.0 16141.0 15496.0 18972.0 13903.0 18859.0 14947.0 13133.0 12692.0 14586.0 13605.0 True False 15910.826380103119 15460.119964071393 17412.19539403783 14925.472999048408 17749.750698220563 14307.751653158806 13812.96247973748 13281.716654423974 12943.171082610717 15956.60612247701 0.9971309849962766 0.9688852281873243 1.0912217335182843 0.9353789198333277 1.1123763137336373 0.8966663426632075 0.8656579208457166 0.8323647618095243 0.81114812155315 1.0 13.961866210875034 -6.919911833385829 7.401659033163575 0.865802863672228 1.0169582256198282 0.5127444260831927 0.06791638741439303 0.17256484826109916 13.531643381317824 0.02268450548102758 0.019993539328804554 1.2025085324570865e-07 6.919911833385829 0.15115536194760015 VSEPLLSATSAS(ph)PTQVVSQLPMGR ddPTM_PC-9_AZD4547_30min_R2 1 VSEPLLSATSASPTQVVSQLPMGR 24 0 W0Z7M9;A0A499FIJ6;Q969V6;E7ER32;A0A087X287;A0A494BZX7 W0Z7M9 mkl1;MKL1 MKL/myocardin-like protein 1 1 VS(0.002)EPLLS(0.059)AT(0.149)S(0.288)AS(0.419)PT(0.069)QVVS(0.013)QLPMGR 53.088 0.0097652 3037500.0 12799.0 8480.1 10549.0 17867.0 17231.0 13649.0 11856.0 14815.0 12097.0 15749.0 True False 16868.815764261828 11221.12648760619 10409.11336740584 13748.03919239827 14838.77307871023 12795.525872325445 12911.161031884654 12525.682164832206 12736.422723485035 15197.632303622515 1.1099634092503323 0.7383470177082464 0.6849167791041186 0.904617174421392 0.9763871623064109 0.8419420615456986 0.8495508230454518 0.8241864202653842 0.8380530907073712 1.0 13.891558957830583 -10.642970718174526 4.68188712674456 1.0000108885228711 0.8565835074536396 0.11570828947962863 0.11223530408675407 1.2795467339599003e-05 2.4048000260475026e-06 0.10900613083340499 0.026435863268434442 2.275250831873367e-11 10.642970718174526 -0.14342738106923147 VSEPLLSATSAS(ph)PTQVVSQLPMGR ddPTM_PC-9_Lapatinib_30min_R1 1 VSEPLLSATSASPTQVVSQLPMGR 24 0 W0Z7M9;A0A499FIJ6;Q969V6;E7ER32;A0A087X287;A0A494BZX7 W0Z7M9 mkl1;MKL1 MKL/myocardin-like protein 1 1 VSEPLLS(0.003)AT(0.07)S(0.145)AS(0.771)PT(0.01)QVVSQLPMGR 89.583 8.116e-06 1539700.0 7648.1 4750.8 7275.3 6618.1 6188.1 8755.6 8114.0 6267.6 8631.3 5948.9 True False 7539.036691510233 4739.79981448828 6677.152917470138 7104.817151334406 5824.128124272696 8381.143398300472 8534.103217893091 6558.815576998718 7659.152102381592 6977.1594385890085 1.0805309464212063 0.6793308732882863 0.9570016245494397 1.0182965164934248 0.834742014359143 1.2012257240312385 1.2231486599966452 0.9400409485733506 1.097746463986568 1.0 12.768424086432885 -6.755842271639171 24.9999954384516 1.0968546903761023 0.9091297148280488 0.3278960900077882 0.12757125779279874 161.72264990275005 722348.3327126203 0.04268059407194437 0.04153623339846688 1.7545175970596964e-07 6.755842271639171 -0.18772497554805345 VSESEGKLEGQATAVT(ph)PNK ddPTM_PC-9_Lapatinib_30min_R1 1 VSESEGKLEGQATAVTPNK 19 1 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 VSESEGKLEGQAT(0.002)AVT(0.998)PNK 111.66 8.8333e-05 7645100.0 31954.0 49554.0 41081.0 48183.0 58065.0 48337.0 48024.0 47501.0 43320.0 31478.0 True False 31498.330100354087 49439.26075758865 37703.47875724585 51726.53855377611 54649.73086018225 46269.73918905043 50510.44773676331 49708.06987092604 38440.84542017666 36918.93035820153 0.8531755875575291 1.3391303669394024 1.0212505723061946 1.4010844315343247 1.4802631151539263 1.2532795165007165 1.368144939376404 1.346411431442878 1.0412231624050028 1.0 15.172073134340481 -4.755566651339876 24.98771077163225 1.2694624028509731 0.8531749107876968 0.33985240170458697 0.1639660029677532 209.88435750837996 892941.7399803624 0.03988877240088847 0.34913582916054664 1.75563143609626e-05 4.755566651339876 -0.4162874920632763 VSESEGKLEGQATAVT(ph)PNKNSSCGGGISSSSSSR ddPTM_PC-9_Lapatinib_30min_R1 1 VSESEGKLEGQATAVTPNKNSSCGGGISSSSSSR 34 2 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 VSESEGKLEGQAT(0.067)AVT(0.719)PNKNS(0.078)S(0.078)CGGGIS(0.011)S(0.025)S(0.011)S(0.005)S(0.002)S(0.002)R 47.43899999999999 0.0045893 10111000.0 10033.0 6864.1 7710.7 7158.1 5908.8 5593.5 4862.1 4589.0 6835.5 3441.0 True False 9889.927580173142 6848.206598179048 7076.756010162742 7684.530552721605 5561.256001147768 5354.279044085349 5113.835747561991 4802.2216929681435 6065.614008993942 4035.7722651557106 2.4505663180158566 1.6968763716688129 1.7535072707799837 1.9041041089133695 1.3779905395462646 1.3267049507013664 1.2671269366991118 1.189913943963055 1.502962409787985 1.0 11.978629051474975 -1.5228787452804002 0.26455433778311804 1.1111514357803478 9.29399252918018 0.7924693020823218 0.18183139946948332 23.185542902347322 0.3217888898287627 0.21906992146973167 86.03180432899256 0.02999999999999567 1.5228787452804002 8.182841093399832 up VSESPS(ph)PVTTNTPAQFASVSPTVPEFLK ddPTM_PC-9_AZD4547_30min_R2 2 VSESPSPVTTNTPAQFASVSPTVPEFLK 28 0 Q9ULH7-4;Q9ULH7;Q9ULH7-5;I3L2S3;Q9ULH7-2;Q9ULH7-3 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2;Phosphatase and actin regulator 1 VS(0.004)ES(0.016)PS(0.343)PVT(0.193)T(0.193)NT(0.251)PAQFASVSPTVPEFLK;VS(0.008)ES(0.059)PS(0.624)PVT(0.094)T(0.094)NT(0.116)PAQFAS(0.004)VS(0.001)PTVPEFLK 82.05799999999999 3.8018e-06 10443100.0 54881.0 52145.0 59835.0 99265.0 75531.0 82359.0 58011.0 77590.0 64228.0 67690.0 True False 72332.01640428585 68999.85149894744 59041.54880450549 76380.98787896206 65044.82440996243 77209.07871044391 63173.866617802036 65600.24834082555 67622.96095593921 65320.19370323253 1.1073454058160015 1.0563326222275549 0.9038789608118335 1.169331925529519 0.9957843160337034 1.1820093348348877 0.9671414464081071 1.0042874128461006 1.0352535276176427 1.0 15.995241448683574 VSESPS(ph)PVTTNTPAQFASVSPTVPEFLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSESPSPVTTNTPAQFASVSPTVPEFLK 28 0 Q9ULH7-4;Q9ULH7;Q9ULH7-5;I3L2S3;Q9ULH7-2;Q9ULH7-3 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2;Phosphatase and actin regulator 1 VS(0.001)ES(0.02)PS(0.587)PVT(0.108)T(0.108)NT(0.175)PAQFASVSPTVPEFLK 114.52 2.3792e-12 2288400.0 30123.0 28455.0 26813.0 33927.0 46709.0 43148.0 47297.0 45502.0 43700.0 40084.0 True False 35222.22894363044 31279.82434745635 27452.323608868774 32026.180182818054 37556.706753362036 40885.24292228715 42816.685759373344 44307.62071335415 44339.02982772236 47350.91189523058 0.7438553458392466 0.6605960285763157 0.5797633563976602 0.6763582558595643 0.7931569900165942 0.8634520706327794 0.9042420524890895 0.9357289847213488 0.936392311215202 1.0 15.531104589278145 -6.662077915682906 1.3660704764384937 0.9429517039667206 0.6543741630717981 0.8914380136980893 0.04389320743160833 0.1341598867786764 0.5230550454723585 0.020881187944005456 0.020594959060353003 2.1773191099539442e-07 6.662077915682906 -0.2885775408949225 VSESPS(ph)PVTTNTPAQFASVSPTVPEFLK ddPTM_PC-9_Lapatinib_30min_R1 1 VSESPSPVTTNTPAQFASVSPTVPEFLK 28 0 Q9ULH7-4;Q9ULH7;Q9ULH7-5;I3L2S3;Q9ULH7-2;Q9ULH7-3 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2;Phosphatase and actin regulator 1 VS(0.011)ES(0.074)PS(0.629)PVT(0.082)T(0.082)NT(0.109)PAQFAS(0.007)VS(0.002)PT(0.002)VPEFLK 73.968 1.9575e-05 2348800.0 11798.0 9338.3 11681.0 12957.0 21809.0 21561.0 19369.0 14218.0 21837.0 16413.0 True False 11629.758356511773 9316.677740093439 10720.633269963948 13909.901003284911 20526.237498143713 20638.886291145842 20371.83204675514 14878.62018536087 19377.4871061957 19249.965181052205 0.6041443840095346 0.4839841346447666 0.5569170213625269 0.7225935669211737 1.0662999805499778 1.0721518764855096 1.058278903631846 0.7729167323380896 1.0066245275741597 1.0 14.232568215841729 -6.034958898774763 3.108761035659322 0.990756175208307 0.5442961458324321 0.8469591312847111 0.08629551632232037 0.09987827126632619 1.950376587515227 0.02839439347140532 0.04077728353555198 9.226587425869467e-07 6.034958898774763 -0.4464600293758749 VSESPSPVTTNTPAQFAS(ph)VSPTVPEFLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSESPSPVTTNTPAQFASVSPTVPEFLK 28 0 Q9ULH7-4;Q9ULH7;Q9ULH7-5;I3L2S3;Q9ULH7-2;Q9ULH7-3 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2;Phosphatase and actin regulator 1 VSESPSPVTTNTPAQFAS(0.827)VS(0.153)PT(0.02)VPEFLK 112.42 3.0436e-11 3799900.0 18017.0 23679.0 22085.0 26823.0 30322.0 25168.0 25805.0 26027.0 22616.0 16778.0 True False 21066.922248029394 26029.694630940758 22611.5901578289 25320.19427133933 24380.621768298268 23848.145774268174 23360.5635879787 25343.818827885993 22946.71621473156 19819.718585425075 1.06292741530253 1.3133231190316872 1.1408633306457185 1.277525418042977 1.230119472343425 1.2032535008749066 1.1786526376392386 1.2787173903933835 1.1577720498819797 1.0 14.274648857800694 -8.54470107205887 20.661144971623877 0.9999999975042168 1.2136366969383539 0.4562477544373379 0.06918618038409888 363.93425522048364 344569.9041487046 0.06041839361487568 0.015599962147070226 2.852981318908314e-09 8.54470107205887 0.2136366994341371 VSESPSPVTTNTPAQFASVS(ph)PTVPEFLK ddPTM_PC-9_AZD4547_30min_R2 1 VSESPSPVTTNTPAQFASVSPTVPEFLK 28 0 Q9ULH7-4;Q9ULH7;Q9ULH7-5;I3L2S3;Q9ULH7-2;Q9ULH7-3 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2;Phosphatase and actin regulator 1 VSESPSPVTTNTPAQFAS(0.206)VS(0.693)PT(0.101)VPEFLK 115.52 2.1529e-12 5876800.0 61083.0 59737.0 87449.0 100460.0 95309.0 84911.0 69620.0 95652.0 69052.0 80174.0 True False 80506.12339467175 79045.81702929587 86289.36912183839 77300.49909152796 82076.99050309278 79601.50174701642 75816.04512818888 80871.18126429501 72701.94774754804 77367.1326630664 1.0405726646905173 1.0216976422473887 1.1153233440565558 0.9991387354132844 1.060876727337664 1.0288800813348051 0.9799515959621704 1.0452911783158454 0.9397006874245266 1.0 16.239433186040493 -7.235293092727293 1.02850084798788 0.9861719246674774 1.049820109062523 0.32850149447494537 0.03727400038063561 0.6512208257187885 1.3471765725670701 0.025471864912643704 0.014813511479863182 5.817105057522348e-08 7.235293092727293 0.0636481843950456 VSESPSPVTTNTPAQFASVS(ph)PTVPEFLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSESPSPVTTNTPAQFASVSPTVPEFLK 28 0 Q9ULH7-4;Q9ULH7;Q9ULH7-5;I3L2S3;Q9ULH7-2;Q9ULH7-3 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2;Phosphatase and actin regulator 1 VSESPSPVTTNTPAQFAS(0.428)VS(0.499)PT(0.072)VPEFLK 83.29299999999999 1.4950999999999999e-06 4266200.0 16929.0 16518.0 20617.0 21100.0 25206.0 22812.0 22428.0 21381.0 20671.0 19218.0 True False 19794.745337008917 18157.79787634102 21108.587470407914 19917.835407122962 20267.065242784993 21615.698561769124 20303.457475341467 20819.771405042087 20973.274269310055 22702.0712703957 0.8719356529737426 0.7998300093445407 0.9298088803876788 0.8773576282925568 0.8927407989073649 0.9521465378340502 0.8943438346886828 0.9170868665270998 0.9238484902767415 1.0 14.470536310334637 -1.5228788040461565 0.056315670223260804 1.1496385366056467 0.41297300172304036 0.5900727857198064 0.03235557827818334 269.48625043979524 1.1427108641195767 3.2057709917635098 16.597666508859568 0.029999995940601314 1.5228788040461565 -0.7366655348826063 VSFELFADK ddPTM_PC-9_AZD4547_30min_R2 2 VSFELFADK 9 0 P62937;F8WE65;C9J5S7 P62937 PPIA Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase 0 ; 129.38 0.0059886 19823800.0 57616.0 71371.0 76284.0 62664.0 70422.0 78671.0 70255.0 94269.0 68857.0 70143.0 False True 75936.68951275176 94440.28001402595 75272.42431691985 48217.782949149 60645.12087220306 73751.68993345421 76507.55889803103 79701.89213611637 72496.64044564836 67687.31491986745 1.1218747501308104 1.3952434089877899 1.1120610177258785 0.7123606986956459 0.8959599142616103 1.0895939663253913 1.1303086699273792 1.1775011644422968 1.0710520949379436 1.0 16.046597867457052 -5.516121234484558 24.85941568782121 1.0133890446102862 1.2573324070003755 0.3365148951835203 0.1384522869492669 329.20424546863364 1211068.8892479164 0.040969070766882214 0.07457732177286593 3.04704428020525e-06 5.516121234484558 0.2439433623900893 VSFELFADK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSFELFADK 9 0 P62937;F8WE65;C9J5S7 P62937 PPIA Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase 0 131.5 0.0056744 4490100.0 25348.0 29943.0 24762.0 23056.0 30040.0 22613.0 28960.0 19374.0 19811.0 19915.0 False True 29638.91575417933 32915.54315360697 25352.419990407943 21764.247068560548 24153.87764394433 21427.13447208861 26216.699147756764 18865.453028449803 20100.698396270207 23525.43185294675 1.2598670213344805 1.399147244537576 1.0776601317621444 0.9251369838651613 1.0267134645997524 0.9108072746985383 1.1143982100576366 0.8019173950291056 0.8544242044913803 1.0 14.521933586090347 -5.4442351674966005 3.5372765331238774 0.9494421363880011 1.3275770376077307 0.7393499433931572 0.08944995162454518 0.11577940644577688 2.7420971308740523 0.02454999928062476 0.05467672679683209 3.595545860795196e-06 5.4442351674966005 0.3781349012197296 VSFELFADK ddPTM_PC-9_Lapatinib_30min_R1 2 VSFELFADK 9 0 P62937;F8WE65;C9J5S7 P62937 PPIA Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase 0 ; 156.35 0.0004086 34114000.0 91333.0 86739.0 105740.0 94864.0 96796.0 82236.0 107923.0 119894.0 105150.0 99493.0 False True 90030.57467157909 86538.1611747284 97046.46536820395 101840.61501702733 91102.64958825806 78718.9579814791 113510.7248687054 125464.71293456599 93306.89972141208 116690.23248391083 0.771534795630752 0.7416058682260336 0.8316588569791791 0.8727432695026042 0.7807221534229031 0.6745976617394503 0.9727525813641358 1.0751946436636415 0.7996119103994173 1.0 16.832324280239817 -7.284137648041824 24.66932667753675 0.9681560418259942 0.7838780914049811 0.5522424998600637 0.08060462144779637 529.628004122553 575616.8155902291 0.03367142275798239 0.022721212550892617 5.198312118265578e-08 7.284137648041824 -0.18427795042101314 VSFELFADKVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSFELFADKVPK 12 1 P62937;F8WE65;C9J5S7 P62937 PPIA Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase 0 96.604 0.0054852 5720500.0 15557.0 13287.0 12962.0 20214.0 23614.0 22915.0 20709.0 22219.0 19762.0 20787.0 False True 18190.492835244117 14606.04554927614 13271.063238658748 19081.47511467222 18987.006214517365 21713.297060448 18747.293599823715 21635.77479297647 20050.981863969093 24555.518550198554 0.7407904173580171 0.594817230978738 0.5404513535940555 0.7770748182598624 0.7732276626821158 0.8842532490633324 0.7634655957885331 0.881096228888293 0.8165570530705393 1.0 14.583759668460223 -6.032145008236379 2.5129577758726414 0.8460769564654238 0.6239371490342834 0.6103649336412595 0.08000751337665793 0.19015602566339848 2.3959001199675636 0.02399804560316058 0.035588419962982364 9.286562624369597e-07 6.032145008236379 -0.22213980743114037 VSFELFADKVPK ddPTM_PC-9_Lapatinib_30min_R1 1 VSFELFADKVPK 12 1 P62937;F8WE65;C9J5S7 P62937 PPIA Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase 0 77.67399999999999 0.022434 3047100.0 13991.0 9618.2 10487.0 9602.3 13120.0 10721.0 10618.0 10880.0 10918.0 11358.0 False True 13791.485774364832 9595.929648840443 9624.79934099066 10308.485174333777 12348.307394912445 10262.487821871653 11167.748085726995 11385.524519392766 9688.299868363078 13321.215166416316 1.0353023806066957 0.7203494222533415 0.7225166188483637 0.7738397019757 0.926965538852894 0.770386762293584 0.8383430450010029 0.854691135692819 0.7272834908325734 1.0 13.701438071162855 -11.293032381516902 2.7283694366740585 1.043599010618436 0.8151801914008682 0.24210970773833984 0.0959521264217542 54996133.401544265 44590500.81557981 16096084.073139455 0.02303723195385975 5.0929289615296145e-12 11.293032381516902 -0.2284188192175679 VSFPSYLAS(ph)PAGSR ddPTM_PC-9_AZD4547_30min_R2 2 VSFPSYLASPAGSR 14 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 VS(0.001)FPSYLAS(0.911)PAGS(0.088)R;VS(0.001)FPSYLAS(0.999)PAGSR 123.72 4.0345e-05 9987600.0 20436.6 16106.5 25295.0 37834.0 33416.0 30587.0 26652.0 37807.0 29796.0 32400.0 True False 26935.013692312932 21312.611145225772 24959.571772540614 29111.955829473085 28776.76520214619 28674.39005471598 29023.97636823464 31964.79686843138 31370.955730260383 31265.685861792477 0.8614880163312922 0.6816613983597387 0.798305589164826 0.9311152155164679 0.9203944966808544 0.9171201355207393 0.9283012852023416 1.0223603284997254 1.0033669457607053 1.0 14.932292544921115 -6.062571760340278 0.6983820517466193 0.9953588040086399 0.743307061094991 0.696087031240164 0.054356770636403054 0.504124255825369 0.49198394141803764 0.03269440455687321 0.07794320873788302 8.658212481808978e-07 6.062571760340278 -0.25205174291364885 VSFPSYLAS(ph)PAGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSFPSYLASPAGSR 14 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 VSFPS(0.004)YLAS(0.995)PAGS(0.001)R;VSFPS(0.001)YLAS(0.986)PAGS(0.013)R 127.07 2.9933000000000003e-05 3549800.0 15920.2 20258.0 21846.0 23274.0 25559.0 18407.7 20185.5 25234.0 21894.0 15303.0 True False 18615.175421717136 22269.08035954211 22366.891491416372 21970.03323532608 20550.897426816697 17442.36780709617 18273.383309635497 24571.634237633043 22214.15833062138 18077.312761518646 1.0297534632107181 1.2318800174186575 1.237290729351599 1.2153373416260134 1.1368336487801216 0.9648761426657345 1.0108462220410452 1.3592525925611534 1.228841843014902 1.0 14.141892612956896 -4.738448449866309 24.292679754610965 1.1587472504735206 1.0297527065385073 0.08611809110542956 0.12040647270054276 3870.8719836467703 4089738.0334771574 0.03202939027892446 1.6842293171975988 1.8262135051408373e-05 4.738448449866309 -0.1289945439350133 VSFPSYLAS(ph)PAGSR ddPTM_PC-9_Lapatinib_30min_R1 1 VSFPSYLASPAGSR 14 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 VSFPS(0.001)YLAS(0.998)PAGSR 83.243 0.008295700000000001 3257300.0 12845.0 10731.0 10649.0 6746.6 10224.0 7726.0 6711.2 9530.7 7412.9 5736.8 True False 12661.82794451549 10706.153028810671 9773.480326328747 7242.7674699978415 9622.64442115739 7395.576990185649 7058.673097846204 9973.531115530932 6577.981140702386 6728.398236194501 1.881848769949869 1.5911889654834015 1.4525716200556682 1.07644750143301 1.4301538172032813 1.0991586304155052 1.0490866993982364 1.4823039251570576 0.9776444422265367 1.0 12.716047382107108 -1.5228787639407892 0.4771702988636038 1.1357886030905464 22.352470881809598 0.6819977486259265 0.1638090855393006 56.18296851326023 0.6342012127068811 0.09220184128496446 1180.4507879934124 0.02999999871098169 1.5228787639407892 21.216682278719052 VSGAGFS(ph)PSSK ddPTM_PC-9_AZD4547_30min_R2 3 VSGAGFSPSSK 11 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 VSGAGFS(0.708)PS(0.282)S(0.009)K;VS(0.002)GAGFS(0.996)PS(0.002)SK;VSGAGFS(0.961)PS(0.034)S(0.005)K 174.72 0.0026006999999999996 462538000.0 349061.0 318040.0 408248.0 533676.0 457140.0 403540.0 352991.0 447606.0 355023.0 434828.0 True False 460055.13708016154 420840.2103888246 402834.3647754958 410645.24341200694 393674.0018107815 378306.5800071954 384406.51516582293 378438.7776626303 373788.7909861803 419604.80407134315 1.0964010245267375 1.0029442139496367 0.9600327757615569 0.9786476213513207 0.9382018460967078 0.9015782858932043 0.9161156198308549 0.9018933386622675 0.8908115144521248 1.0 18.67867166991688 -1.5228825298626927 0.5370648053970288 0.9171357342308549 8.264181191097034 0.7278756018618115 0.03145405795985431 60.8138481890225 0.5799698717356532 0.015513236934952615 512.7273816784138 0.029999738571451665 1.5228825298626927 7.347045456866179 VSGAGFS(ph)PSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 VSGAGFSPSSK 11 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 VSGAGFS(0.629)PS(0.283)S(0.088)K;VSGAGFS(0.763)PS(0.23)S(0.007)K;VS(0.011)GAGFS(0.827)PS(0.16)S(0.002)K;VS(0.131)GAGFS(0.856)PS(0.013)SK;VSGAGFS(0.996)PS(0.004)SK 176.99 0.00097642 373015000.0 334695.0 307182.0 345810.0 373485.0 440152.0 420878.0 432562.0 372617.0 380493.0 338808.0 True False 391352.2529724263 337676.99886488676 354055.42189172853 352559.8463047077 353907.37525757035 398806.41676662565 391586.59588231967 362836.1985703453 386056.99030296446 400231.20839734736 0.9778154345822375 0.8437048180651692 0.8846272216239175 0.8808904425930928 0.8842573188500908 0.9964400786324809 0.9784009534147937 0.906566481967402 0.9645849254206313 1.0 18.610474141542134 -6.748324199198447 24.998070382868644 0.9639340467959501 0.8901726611706007 0.4657405298958004 0.039812775602275995 212.98758134344155 405962.5066281494 0.013026617043289966 0.012949508211786996 1.785154466234121e-07 6.748324199198447 -0.0737613856253494 VSGAGFS(ph)PSSK ddPTM_PC-9_Lapatinib_30min_R1 5 VSGAGFSPSSK 11 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 VSGAGFS(0.946)PS(0.048)S(0.007)K;VSGAGFS(0.91)PS(0.089)S(0.001)K;VSGAGFS(0.591)PS(0.383)S(0.026)K;VS(0.02)GAGFS(0.978)PS(0.002)SK;VSGAGFS(0.991)PS(0.008)SK 152.0 0.00020273 529651500.0 1244974.0 1006301.0 1211016.0 1019135.0 1210554.0 1319178.0 1121748.0 1142373.0 1267998.0 1025178.0 True False 1227220.4424597286 1003970.9718614486 1111450.9391369456 1094085.587634696 1139351.5937607351 1262759.8320941133 1179826.6226848832 1195451.820017672 1125182.7126291136 1202378.6513361798 1.0206605390872023 0.834987356724735 0.9243768075071959 0.9099343093116798 0.9475813567503016 1.0502181078238815 0.9812438214648647 0.9942390599576845 0.9357973142476541 1.0 20.19745986835106 -6.529998992648035 24.77005337796162 0.9920987475976644 0.9179222986064625 0.31020331135010004 0.049265983069872385 177.20767845636695 616467.5901479624 0.015599774667808756 0.015633278526800895 2.9512160720443163e-07 6.529998992648035 -0.0741764489912019 VSGAGFSPS(ph)SK ddPTM_PC-9_AZD4547_30min_R2 2 VSGAGFSPSSK 11 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 VSGAGFS(0.286)PS(0.626)S(0.088)K;VSGAGFS(0.315)PS(0.658)S(0.027)K 104.59 0.0026634000000000002 44951000.0 93074.0 103235.0 124069.0 159425.0 141071.0 121855.0 104535.0 123838.0 107551.0 128748.0 True False 122669.59594053494 136603.69487954446 122423.76399475537 122672.02934169666 121485.7267127111 114235.38758679882 113838.41248887173 104701.68261414045 113235.9262902818 124240.5717078414 0.9873553723577456 1.0995095483042014 0.9853766954859291 0.987374958561578 0.9778265267354976 0.9194692685045726 0.9162740554395474 0.8427334257633027 0.9114247039732106 1.0 16.922776848023616 -6.332255266510951 1.0457939736284665 0.9041102727756083 1.0364701142633688 0.4888900521506113 0.04694213916797377 0.38313715753394384 0.8842495332308767 0.02091266809183094 0.02965065522994469 4.65312515060737e-07 6.332255266510951 0.13235984148776048 VSGAGFSPS(ph)SK ddPTM_PC-9_Lapatinib_30min_R1 1 VSGAGFSPSSK 11 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 VSGAGFS(0.282)PS(0.553)S(0.164)K 105.65 0.0025316999999999996 13897000.0 67579.0 56044.0 66825.0 74673.0 65041.0 73053.0 60071.0 57156.0 69069.0 56749.0 True False 66615.3110675292 55914.23356133308 61330.90645195962 80164.70152182561 61215.416255525946 69928.69348486053 63181.182450339635 59811.676418236464 61289.721891186084 66557.9890367106 1.0008612344160066 0.8400829768233101 0.921465737465897 1.2044339482313704 0.9197305558880706 1.0506431233415239 0.9492651951291909 0.8986400773804456 0.9208469603458308 1.0 16.022324224527964 -10.278271515899249 12.659099503019666 0.9999999779467018 0.9677109129801342 0.010313777803252377 0.09594340344804686 0.0 0.0 0.0950328064478646 0.0230488411107897 5.269003464117998e-11 10.278271515899249 -0.03228906496656758 VSGEEELHTGPPAPQGPLSVPQGLPTQSLAS(ph)PPAR ddPTM_PC-9_AZD4547_30min_R2 4 VSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPAR 35 0 Q9UPN7 Q9UPN7 PPP6R1 Serine/threonine-protein phosphatase 6 regulatory subunit 1 1 VSGEEELHTGPPAPQGPLS(0.002)VPQGLPT(0.029)QS(0.029)LAS(0.939)PPAR;VSGEEELHTGPPAPQGPLS(0.001)VPQGLPT(0.026)QS(0.026)LAS(0.947)PPAR;VSGEEELHTGPPAPQGPLSVPQGLPT(0.002)QS(0.006)LAS(0.992)PPAR;VSGEEELHTGPPAPQGPLSVPQGLPT(0.024)QS(0.024)LAS(0.952)PPAR 121.94 1.4969999999999998e-24 94610000.0 98618.0 96266.0 130132.0 172278.0 163087.0 152442.0 105315.0 151157.0 120240.0 131309.0 True False 129976.47261817093 127382.10191576708 128406.36465326161 132561.9687685672 140445.18513653384 142909.7776415145 114687.83097781155 127799.1588923076 126595.64092517491 126711.91187734916 1.0257636452047356 1.0052890847315652 1.013372482119539 1.0461681684424475 1.108381864464943 1.1278322260644607 0.9051069412386712 1.0085804641319818 0.9990823991963218 1.0 16.95119262952788 -7.262192593788785 24.998509272764053 0.978907493976956 1.052437907683085 0.4047811903200571 0.045269093410693594 81.9273839376725 2719015.0201409357 0.01993611666380596 0.014354226982530503 5.467734350130044e-08 7.262192593788785 0.073530413706129 VSGEEELHTGPPAPQGPLSVPQGLPTQSLAS(ph)PPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPAR 35 0 Q9UPN7 Q9UPN7 PPP6R1 Serine/threonine-protein phosphatase 6 regulatory subunit 1 1 VSGEEELHTGPPAPQGPLSVPQGLPT(0.037)QS(0.02)LAS(0.942)PPAR;VSGEEELHTGPPAPQGPLSVPQGLPT(0.033)QS(0.033)LAS(0.934)PPAR;VSGEEELHTGPPAPQGPLSVPQGLPT(0.007)QS(0.006)LAS(0.987)PPAR;VSGEEELHTGPPAPQGPLS(0.001)VPQGLPT(0.066)QS(0.066)LAS(0.868)PPAR 127.78 3.5857e-24 61371000.0 72857.0 77017.0 87347.0 88567.0 110740.0 102600.0 110162.0 102009.0 102279.0 79894.0 True False 85190.25110865734 84662.73877237923 89429.68374534199 83604.87812808831 89041.29195374135 97219.47538302264 99726.65785618708 99331.37183746976 103774.63688214212 94378.14975944377 0.9026480316237916 0.8970586834788804 0.9475676729548661 0.8858499381603161 0.9434524005894872 1.0301057567966845 1.056671042083108 1.0524827207425769 1.0995621035869916 1.0 16.526165267923545 -6.7454629858966015 2.616074372719333 1.0559234625384328 0.9099840647542159 0.8598517348691944 0.02710677651791082 0.09150738544823298 1.2837156178739022 0.009722838300132555 0.009097391251486236 1.796954224682468e-07 6.7454629858966015 -0.14593939778421694 VSGEEELHTGPPAPQGPLSVPQGLPTQSLAS(ph)PPAR ddPTM_PC-9_Lapatinib_30min_R1 4 VSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPAR 35 0 Q9UPN7 Q9UPN7 PPP6R1 Serine/threonine-protein phosphatase 6 regulatory subunit 1 1 VSGEEELHTGPPAPQGPLSVPQGLPT(0.007)QS(0.007)LAS(0.985)PPAR;VSGEEELHTGPPAPQGPLSVPQGLPT(0.013)QS(0.009)LAS(0.978)PPAR;VSGEEELHTGPPAPQGPLSVPQGLPT(0.007)QS(0.082)LAS(0.912)PPAR;VSGEEELHTGPPAPQGPLSVPQGLPT(0.024)QS(0.014)LAS(0.963)PPAR 130.15 1.9870999999999998e-24 59821600.0 100299.0 91097.0 106616.0 83455.0 114237.0 109600.0 107570.0 98292.0 129298.0 88483.0 True False 98868.71786741614 90886.0704934832 97850.44402966149 89592.55909771874 107517.80425858345 104912.66349007867 113139.44825594756 102859.0051525878 114735.09767169907 103777.16865381374 0.9527020167338395 0.8757809802719376 0.942889898606475 0.8633166645409945 1.036044880133972 1.0109416632867754 1.0902152151921303 0.9911525481651092 1.1055909422084877 1.0 16.66312955500191 -6.27546634726208 24.417410500408852 1.0397072718132343 0.9087671141838487 0.6946491720469198 0.04232644821487704 300.9130696712259 523812.5289627093 0.012072188610936034 0.013759757589413142 5.303146842165945e-07 6.27546634726208 -0.1309401576293856 VSGGT(ph)PIKIEDPNQFVPLNTNPNEVLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSGGTPIKIEDPNQFVPLNTNPNEVLEK 28 1 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 VS(0.008)GGT(0.992)PIKIEDPNQFVPLNT(0.001)NPNEVLEK 68.309 0.00015212 8524600.0 12416.0 12528.0 14697.0 11268.0 14696.0 11768.0 10135.0 8559.7 9746.6 7245.0 True False 14517.783572821934 13771.697045332394 15047.432218682887 10636.690491348892 11816.424296118714 11150.865363619978 9174.939428954245 8335.016944751827 9889.125586244372 8558.461148611555 1.6963077030707983 1.609132390297359 1.7581936702632623 1.242827455386006 1.3806716056701034 1.3029054137178608 1.0720314399560837 0.9738920116619355 1.1554794038936183 1.0 13.06313570128309 -6.263175036623925 0.6047408350387043 1.0115336221580895 1.7674187594148862 0.8349521099780929 0.11035696597550393 0.37533385801555486 0.28587821556049026 0.07859957183853856 0.15496333374324578 5.455379449526059e-07 6.263175036623925 0.7558851372567967 VSGIAEVEET(ph)GRSMLVLK ddPTM_PC-9_AZD4547_30min_R2 1 VSGIAEVEETGRSMLVLK 18 1 Q96PF1 Q96PF1 TGM7 Protein-glutamine gamma-glutamyltransferase Z 1 VSGIAEVEET(0.997)GRS(0.003)MLVLK 114.69 0.0035633 0.0 33152.0 40342.0 55500.0 55307.0 58358.0 76086.0 64692.0 87486.0 75028.0 57940.0 True False 43693.6463955628 53381.76256919246 54764.03373694418 42556.82563463205 50255.99903240503 71328.33039209852 70449.46267499003 73967.04892828294 78993.82690730224 55911.538235563436 0.7814781666616847 0.9547539605204088 0.9794764276778676 0.7611456772184295 0.8988484419918694 1.2757354321317704 1.2600165350160142 1.3229299579748461 1.4128358725258061 1.0 15.77085841641953 -6.753194954004606 6.541066506063075 1.2759333852242036 0.8775643573286926 0.7233719373258239 0.11689562277958364 0.07432155573062756 13.72177197644074 0.03870394846613232 0.036803129569105385 1.765245227424275e-07 6.753194954004606 -0.398369027895511 VSGREENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSGREENR 8 1 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 0 87.75399999999999 0.014891999999999999 4068500.0 3493.4 3897.7 2970.6 3470.2 4700.9 4051.8 5560.1 5254.5 5167.1 4303.7 False True 4084.76362220491 4284.637896998087 3041.4303700632368 3275.775944540195 3779.792390693008 3839.316475213755 5033.40707636196 5116.574942602948 5242.659062307194 5083.926741929545 0.8034662632952468 0.8427812032893107 0.5982443344391893 0.6443397221921637 0.7434789253588718 0.755187214549946 0.9900628651567842 1.0064218471922772 1.0312223854581752 1.0 12.311727526292051 -7.2493788464227915 3.3292613863237412 1.0135465369472947 0.7227242922309906 0.8079162086076481 0.06602366662448975 0.11635667575455784 2.711808051370382 0.031795153515157076 0.02220246010274979 5.631461943618775e-08 7.2493788464227915 -0.29082224471630413 VSGRT(ph)SPPLLDR ddPTM_PC-9_AZD4547_30min_R2 1 VSGRTSPPLLDR 12 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 VS(0.229)GRT(0.385)S(0.385)PPLLDR 69.045 0.023841 285080000.0 36414.0 16463.0 49750.0 121380.0 90739.0 39373.0 32465.0 40364.0 37046.0 49430.0 True False 47992.89454174781 21784.342798488316 49090.28249392749 93397.71630230588 78141.45611915075 36911.000085798936 35354.322106961496 34126.67127244596 39004.17592909204 47699.47074532104 1.0061515105270964 0.4566998848855193 1.029157802526412 1.958045128026237 1.6382038395429332 0.7738241013799849 0.74118898081127 0.715451780474808 0.8177066814293333 1.0 15.5416856382889 -6.860372032744441 24.73632197049452 0.7875550151220277 1.2061831725830645 0.22309100317152064 0.3792884635052302 21.726699107350356 5406.451862421205 0.15374421826549098 0.13558969680959895 1.3792022826336357e-07 6.860372032744441 0.41862815746103677 VSGRT(ph)SPPLLDR ddPTM_PC-9_Lapatinib_30min_R1 1 VSGRTSPPLLDR 12 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 VS(0.007)GRT(0.974)S(0.019)PPLLDR 122.1 0.00030025 226610000.0 305710.0 72029.0 135920.0 115500.0 91039.0 78787.0 45957.0 48733.0 99642.0 59516.0 True False 301350.5193396526 71862.22127594854 124745.18226637275 123994.255296705 85684.26500956062 75417.46367146737 48336.428590672025 50997.31308856317 88419.26868322342 69803.26129991491 4.317140972036788 1.0294966157410204 1.7870967622901712 1.776338998889385 1.2275109130132444 1.080428940811671 0.69246662248331 0.7305863958053395 1.2666925160319293 1.0 16.091006822163447 -4.759659515735977 24.99985802898767 1.1895711491538492 4.317144879032171 0.8774053236534575 0.3521327155225432 16.870421627466776 236893.22435839323 0.09986063669523661 0.624207118600788 1.739163788362478e-05 4.759659515735977 3.127573729878322 VSGRTS(ph)PPLLDR ddPTM_PC-9_Lapatinib_30min_R1 1 VSGRTSPPLLDR 12 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 VS(0.003)GRT(0.241)S(0.756)PPLLDR 91.712 0.0029517 208860000.0 182380.0 49735.0 86887.0 57446.0 47333.0 50617.0 25926.0 27725.0 67508.0 30561.0 True False 179779.227755604 49619.841663209314 79743.48625351899 61670.770474238256 44548.96600025844 48452.22890399003 27268.32142310772 29013.204715088625 59904.538149244814 35843.428130027205 5.015681733996785 1.384349774893355 2.2247728639190982 1.7205600494048348 1.242876820784291 1.351774409752956 0.7607620935192905 0.8094427968730848 1.6712837268782568 1.0 15.129421005496088 -3.199942504362687 1.302886091560532 1.2695403132852685 199.99999999999955 0.8500718952807331 0.4558874598614293 29.714320580522767 1.204756411259262 0.1360946672611748 16706.24699915983 0.0006310408815675986 3.199942504362687 198.73045968671428 VSGS(ph)PEQAVEENLSSYSLDR ddPTM_PC-9_AZD4547_30min_R2 2 VSGSPEQAVEENLSSYSLDR 20 0 A0A494BZT8;Q9Y6A5;E7EMT0;C9JA91 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 VS(0.016)GS(0.984)PEQAVEENLSSYSLDR;VS(0.059)GS(0.941)PEQAVEENLSSYSLDR 187.59 1.1257999999999999e-11 9348800.0 27688.0 29115.0 30340.0 28305.0 24501.4 37377.0 32194.0 44692.0 36072.0 30977.0 True False 36492.20805382306 38525.85437514346 29937.67177619618 21779.719557890683 21099.803534949267 35039.81028133254 35059.20363195806 37785.878319991956 37978.692277552436 29892.504658665002 1.2207812115618417 1.288813192974644 1.0015109847116168 0.7286013603272067 0.7058559921921104 1.1721938553307367 1.172842625008854 1.2640586244431307 1.2705088687355435 1.0 14.867496163392058 -6.96364023886932 24.98404956124518 1.1950951744011091 0.9866830867900448 0.20132418762583526 0.18460089924501355 294.7704070973984 202546.13646134592 0.07379745358659703 0.06508305069957179 1.0873259704084147e-07 6.96364023886932 -0.20841208761106433 VSGS(ph)PEQAVEENLSSYSLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSGSPEQAVEENLSSYSLDR 20 0 A0A494BZT8;Q9Y6A5;E7EMT0;C9JA91 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 VS(0.063)GS(0.919)PEQAVEENLS(0.005)S(0.008)Y(0.004)SLDR;VS(0.375)GS(0.625)PEQAVEENLSSYSLDR 103.45 0.00018213 6350800.0 16201.4 26050.0 22446.0 17306.300000000003 20828.9 16235.7 19315.5 16712.4 15891.7 12829.900000000001 True False 18943.977027763958 28636.071841547633 22981.197766929043 16336.684118781634 16747.62656650973 15384.271310683638 17485.796007890058 16273.717208251495 16124.086048357343 15155.859308567475 1.249944106900959 1.8894390122346882 1.5163243006576324 1.077912098956121 1.1050265264103134 1.0150708711044212 1.1537317450555569 1.0737574740517752 1.0638846481797664 1.0 13.887588032071779 -5.725665410573793 4.72007734082288 1.0738857134255884 1.5979491399146768 0.6849141305873313 0.1496229941393881 0.09791320231881116 5.000102838884436 0.038835889676207914 0.06658608401668835 1.8807652391155207e-06 5.725665410573793 0.5240634264890884 VSGS(ph)PEQAVEENLSSYSLDR ddPTM_PC-9_Lapatinib_30min_R1 3 VSGSPEQAVEENLSSYSLDR 20 0 A0A494BZT8;Q9Y6A5;E7EMT0;C9JA91 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 VS(0.193)GS(0.806)PEQAVEENLSSYSLDR;VS(0.36)GS(0.639)PEQAVEENLSSYSLDR;VS(0.238)GS(0.762)PEQAVEENLSSYSLDR 112.14 4.4977e-05 7644400.0 26970.9 32123.3 35522.7 33649.3 39201.7 38686.3 38536.1 36763.9 42480.4 34765.8 True False 26586.290020142693 32048.920472499663 32602.160727587387 36123.981772774176 36895.93307950756 37031.77713116996 40531.31069941455 38472.085007215384 37695.81001355662 40775.02220748338 0.6520239249621634 0.785993942797112 0.7995620593826178 0.8859340796666542 0.904866044995951 0.9081975956440699 0.9940230196116459 0.943520884218051 0.9244828812536702 1.0 15.3153980422283 -3.6544779533683447 0.3970451562262261 0.973530509383192 2.432950622801313e-12 0.9283380110324023 0.027055182018793755 3.278534108760313 0.20303486289019546 0.02066021006679423 1.8197492152714734 0.00022157565746684004 3.6544779533683447 -0.973530509380759 VSGS(ph)PEQAVEENLSSYSLDRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSGSPEQAVEENLSSYSLDRR 21 1 A0A494BZT8;Q9Y6A5;E7EMT0;C9JA91 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 VS(0.094)GS(0.884)PEQAVEENLSS(0.003)Y(0.009)S(0.01)LDRR 60.618 0.0044699 7693400.0 5160.0 4143.4 4462.9 5168.8 8209.1 5936.8 7289.7 7782.4 5873.9 4762.3 True False 6033.486085354477 4554.729369223358 4569.312461642503 4879.2088934756985 6600.585784517422 5625.463756860901 6599.166843142353 7578.120246134399 5959.79467517296 5625.66729165394 1.0724925191195653 0.8096336191051697 0.8122258613518415 0.8673120254932845 1.1732982848647733 0.9999638203287741 1.1730460585418312 1.3470615756777966 1.0593933779224236 1.0 12.457808517216154 -6.2583907815708075 24.873063701241417 1.1389180442140738 0.8790608125998898 0.48797782982961035 0.11723567540709169 202.84278694055766 1654963.2708570627 0.035692352496159784 0.044090069301525085 5.51580899112756e-07 6.2583907815708075 -0.25985723161418406 VSGS(ph)PEQAVEENLSSYSLDRR ddPTM_PC-9_Lapatinib_30min_R1 2 VSGSPEQAVEENLSSYSLDRR 21 1 A0A494BZT8;Q9Y6A5;E7EMT0;C9JA91 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 VS(0.101)GS(0.898)PEQAVEENLSSYSLDRR;VS(0.081)GS(0.918)PEQAVEENLSSYSLDRR 70.615 0.0012277000000000002 66503000.0 12963.2 13356.2 18433.4 11441.8 12681.599999999999 13284.7 13661.0 12075.3 12938.5 11980.7 True False 12778.342390840267 13325.27453950248 16917.877006981715 12283.26814072589 11935.693220984884 12716.544349148246 14368.299736213645 12636.362521049934 11481.229881554835 14051.548031720718 0.9093903648191467 0.9483136313110335 1.2039867044392825 0.8741576453353738 0.8494219422686106 0.9049924122553071 1.022542121606664 0.8992861492928702 0.8170793606253554 1.0 13.778441457658346 VSGTLDT(ph)PEKTVDSQGPTPVCTPTFLER ddPTM_PC-9_AZD4547_30min_R2 2 VSGTLDTPEKTVDSQGPTPVCTPTFLER 28 1 H7BZL0;Q9BYG3;C9J808 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 VS(0.003)GT(0.036)LDT(0.813)PEKT(0.11)VDS(0.036)QGPT(0.001)PVCTPTFLER;VS(0.002)GT(0.019)LDT(0.792)PEKT(0.174)VDS(0.01)QGPT(0.002)PVCT(0.001)PTFLER 57.427 0.0018257999999999998 13930600.0 16400.3 19840.8 18864.5 26796.0 22182.0 23635.0 22534.1 24029.0 19247.5 21382.6 True False 21615.254252568426 26253.95059200916 18614.344404154657 20618.596194073078 19102.41218919101 22157.099713708823 24539.591245663974 20315.87018148855 20264.883555449953 20634.001682356902 1.0475551269849195 1.2723634996335973 0.9021199421569713 0.9992533930877306 0.9257735112779661 1.0738149610918295 1.189279308174456 0.9845821714194988 0.9821111710375325 1.0 14.332736018875545 -5.261970147659368 24.999112182081067 1.012268099192979 1.1599593057130826 0.31187817233111204 0.0905539483688305 56.31818823446991 2652759.348824113 0.024132451343872593 0.05575247618577078 5.47053564725864e-06 5.261970147659368 0.14769120652010348 VSGTLDTPEKT(ph)VDSQGPTPVCTPTFLER ddPTM_PC-9_AZD4547_30min_R2 2 VSGTLDTPEKTVDSQGPTPVCTPTFLER 28 1 H7BZL0;Q9BYG3;C9J808 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 VSGTLDT(0.042)PEKT(0.94)VDS(0.015)QGPT(0.002)PVCTPTFLER;VSGT(0.001)LDT(0.061)PEKT(0.904)VDS(0.03)QGPT(0.004)PVCTPTFLER 103.53 3.0262e-10 72010000.0 131299.0 120746.0 140376.0 176919.0 167424.0 140138.0 133768.0 138332.0 141159.0 168508.0 True False 173049.3508111425 159774.78318327584 138514.52251995087 136133.0579213024 144180.067548603 131375.1487065678 145673.092857047 116955.9679531264 148620.37655818998 162608.58620984308 1.0642079538642923 0.9825728573587726 0.8518278508442395 0.8371824704608491 0.886669461368673 0.8079225812653634 0.8958511739906455 0.7192484153462665 0.9139761929077865 1.0 17.31104391238673 -5.077111574162271 2.5244282522577084 0.85222173235836 1.0641329513279303 0.46470782967836266 0.06995624951389061 0.24631283348556135 2.8037505103717635 0.017362283599488642 0.0837553836138466 8.373141409512242e-06 5.077111574162271 0.21191121896957033 VSGTLDTPEKT(ph)VDSQGPTPVCTPTFLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSGTLDTPEKTVDSQGPTPVCTPTFLER 28 1 H7BZL0;Q9BYG3;C9J808 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 VSGT(0.001)LDT(0.073)PEKT(0.924)VDS(0.002)QGPTPVCTPTFLER;VS(0.002)GT(0.006)LDT(0.22)PEKT(0.751)VDS(0.02)QGPT(0.001)PVCTPTFLER 81.79899999999999 5.4505e-06 42768000.0 51312.0 40775.0 47189.0 59138.0 66353.0 54052.0 64845.0 75728.0 56327.0 51194.0 True False 59998.108141804114 44822.872527412845 48314.16472527909 55824.68958798286 53351.605968995944 51217.41796689219 58702.41216285524 73740.22024044838 57150.67581478532 60475.066948518965 0.9921131330516612 0.7411793783638061 0.7989104793618143 0.923102567798811 0.8822082994039997 0.8469179209093295 0.9706878408721276 1.2193491295052512 0.9450287316496296 1.0 15.884052840881443 -7.482252439000132 4.869357239594715 1.0681703599685666 0.8611670212015423 0.46880529806702753 0.09114650828464495 0.1578100746676387 8.902576575000323 0.03960408379868582 0.025051314382797663 3.294181781562541e-08 7.482252439000132 -0.20700333876702426 VSGTLDTPEKT(ph)VDSQGPTPVCTPTFLER ddPTM_PC-9_Lapatinib_30min_R1 1 VSGTLDTPEKTVDSQGPTPVCTPTFLER 28 1 H7BZL0;Q9BYG3;C9J808 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 VSGTLDT(0.073)PEKT(0.89)VDS(0.025)QGPT(0.011)PVCT(0.001)PTFLER 72.122 6.6409e-05 38220000.0 56277.0 58123.0 71329.0 65418.0 66075.0 64637.0 61989.0 55488.0 65561.0 66982.0 True False 55474.47966006216 57988.41976456647 65464.604957902426 70229.05794805071 62188.59840844823 61872.62618620632 65198.48710549351 58066.17504890304 58176.829792063676 78559.74945209529 0.7061437956073139 0.7381441535773615 0.8333097472239507 0.8939572546737242 0.7916089198625822 0.7875868573630754 0.8299222892156841 0.7391339134083038 0.7405424558735278 1.0 16.26150270807176 -11.919616894774196 2.334483579253921 2.7881426336382082 0.7880797442595875 0.5907240049637767 0.05374183739836629 2368124.070204405 500519.51043356076 22170487.499152184 0.014726713478814017 1.2033254589200422e-12 11.919616894774196 -2.0000628893786208 VSGTLDTPEKTVDS(ph)QGPTPVCTPTFLER ddPTM_PC-9_Lapatinib_30min_R1 2 VSGTLDTPEKTVDSQGPTPVCTPTFLER 28 1 H7BZL0;Q9BYG3;C9J808 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 VSGT(0.003)LDT(0.319)PEKT(0.29)VDS(0.352)QGPT(0.033)PVCT(0.001)PT(0.001)FLER;VSGTLDT(0.095)PEKT(0.421)VDS(0.482)QGPT(0.001)PVCTPTFLER 83.221 1.3566999999999999e-06 40246800.0 46250.2 45691.3 49780.9 56176.3 53207.4 48307.9 41612.0 44809.7 56185.0 47589.2 True False 45590.6636667521 45585.504602115136 45688.106561831046 60307.69250064328 50077.845341773216 46241.883728215034 43766.46575092025 46891.722247852376 49856.853645720796 55814.92981137691 0.8168184358705264 0.81672600424597 0.8185642572019918 1.080493923479782 0.8972123679275095 0.8284859245453969 0.784135461583958 0.8401286610288687 0.8932530026322516 1.0 15.768363456511553 VSGVTPQHMVGAT(ph)PFAVARLEVPFPS(ph)SPTAA ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSGVTPQHMVGATPFAVARLEVPFPSSPTAA 31 1 Q96AZ6-2 Q96AZ6-2 2 VS(0.015)GVT(0.019)PQHMVGAT(0.966)PFAVARLEVPFPS(0.37)S(0.332)PT(0.298)AA 44.698 0.017357 100940000.0 28257.0 30420.0 29823.0 39620.0 47707.0 41731.0 47283.0 49878.0 42079.0 35275.0 True False 33040.351998810394 33439.896561223766 30534.09342435734 37400.219849773115 38359.15581756501 39542.55289677305 42804.01194072458 48568.75535010944 42694.325769353105 41670.07826325367 0.7929035263643046 0.8024918107896234 0.7327582451718962 0.8975317880013226 0.9205443669970651 0.9489435716189485 1.0272121801717577 1.1655546947445812 1.0245799275832572 1.0 15.346724189210788 -6.5740113622302685 0.9502621090891964 1.0720287597157108 0.7769900510744546 0.8147581776366339 0.05345015362326967 0.218519457091591 0.42920923338771766 0.02944912534045424 0.032966853576449115 2.6667888937389236e-07 6.5740113622302685 -0.29503870864125614 VSHEQFR ddPTM_PC-9_AZD4547_30min_R2 2 VSHEQFR 7 0 O96013;O96013-2;O96013-4;O96013-3 O96013 PAK4 Serine/threonine-protein kinase PAK 4 0 ; 133.81 0.0035118000000000003 1774560.0 5941.6 6872.2 8599.3 12161.7 11580.6 9032.0 9661.7 9968.2 8108.7 8575.0 False True 7830.9052070425805 9093.504256804435 8485.26766331719 9358.007961391952 9972.833585706665 8467.227612194549 10521.572582807017 8427.843736448216 8537.309327760857 8274.791860026862 0.9463567591193961 1.0989405426295418 1.0254357821744227 1.1309055405487352 1.2052065785343258 1.023255660737195 1.2715211162752873 1.0184961602672695 1.0317249632588514 1.0 13.014507308209302 -4.760894534556424 24.810220367409876 1.0966025062295137 0.9463565714699063 0.19625916898429108 0.08582524890039442 18.934187301340145 861332.1497909399 0.020774715578848052 0.11953839409006922 1.7342250913204342e-05 4.760894534556424 -0.15024593475960746 VSHEQFR ddPTM_PC-9_Lapatinib_30min_R1 2 VSHEQFR 7 0 O96013;O96013-2;O96013-4;O96013-3 O96013 PAK4 Serine/threonine-protein kinase PAK 4 0 ; 145.04 0.0014158 2680200.0 14583.9 11859.599999999999 12500.0 9656.900000000001 13163.0 13071.0 11509.400000000001 12844.4 12510.5 9931.4 False True 14375.93091164029 11832.139824851658 11472.298251395376 10367.100640474044 12388.778219453709 12511.983799989208 12105.30041607329 13441.197714787528 11101.43574859465 11648.02925724132 1.2341942653263078 1.0158061560066807 0.9849132413762872 0.8900304430493294 1.0635943596855135 1.074171735292542 1.0392573841233868 1.1539460811734685 0.9530741641718606 1.0 13.507798263930148 VSHLLGINVTDFTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSHLLGINVTDFTR 14 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 ; 80.507 0.0096646 4363400.0 11644.4 11506.099999999999 12487.099999999999 17370.5 19206.2 18948.4 17474.2 16227.7 15154.1 13542.0 False True 13615.566932616613 12648.34956683421 12784.839821590465 16397.28720092083 15442.88298286032 17954.712547248204 15818.917273747635 15801.740069669408 15375.70004375944 15997.05740158698 0.8511294665521353 0.7906672614414346 0.7991994715429446 1.0250189637560558 0.9653577276861128 1.1223759530591555 0.9888641939972239 0.9877904212622131 0.9611580216142814 1.0 13.96551893075179 -5.760762587034918 24.999997958862476 1.0090035199926966 0.8113655462761182 0.7940327346544751 0.04516438317183228 7.5526995881038586 278964.9611258673 0.012707418021019816 0.020434629099041784 1.7347520643230868e-06 5.760762587034918 -0.19763797371657832 VSHS(ph)PPPK ddPTM_PC-9_AZD4547_30min_R2 1 VSHSPPPK 8 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 VS(0.013)HS(0.987)PPPK 63.32 0.033143 119690000.0 139080.0 133370.0 154460.0 197290.0 193540.0 179440.0 148990.0 175880.0 162690.0 178660.0 True False 183304.54695628802 176479.24430750086 152411.75947762877 151807.83860011495 166670.31174357687 168219.58843359037 162249.82136812538 148701.78732032957 171289.4612617823 172405.1677798718 1.0632195619004452 1.0236308260366702 0.8840324303516774 0.8805295140221339 0.9667361709040112 0.9757224252603286 0.9410960440309258 0.8625135153152319 0.9935285784500727 1.0 17.395443493751607 -5.0917672352819805 5.074855803360378 0.9338231572680377 1.0547720144046824 0.4605842030547498 0.04625247640604502 0.16884506778543312 6.890125169144674 0.011903893644738964 0.03456492932733076 8.095296589062711e-06 5.0917672352819805 0.12094885713664472 VSHS(ph)PPPK ddPTM_PC-9_Lapatinib_30min_R1 1 VSHSPPPK 8 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 VS(0.002)HS(0.998)PPPK 67.704 0.025841000000000003 99930000.0 129220.0 144750.0 153030.0 123780.0 156700.0 155320.0 134020.0 146900.0 166990.0 123200.0 True False 127377.29910395396 144414.84026841322 140448.46411288276 132883.19411797548 147483.21408405347 148677.32566860397 140958.89983510363 153725.51028481615 148181.82771734282 144494.95584631863 0.8815345723170392 0.9994455475802864 0.9719956194336665 0.9196389821337906 1.0206807097191204 1.0289447461870822 0.9755281698900558 1.0638814994228236 1.025515574916992 1.0 17.140659605207617 -6.277599306412437 23.644870948871542 1.0206003374049755 0.9492346692132873 0.5142282131452953 0.03594625223170476 342.83117758021615 501621.97270078445 0.010996688958583493 0.012513056192372736 5.277165245508504e-07 6.277599306412437 -0.07136566819168821 VSHYIINSSGPRPPVPPS(ph)PAQPPPGVSPSR ddPTM_PC-9_AZD4547_30min_R2 1 VSHYIINSSGPRPPVPPSPAQPPPGVSPSR 30 1 I3L297;P46108-2;P46108 I3L297 CRK Adapter molecule crk 1 VSHYIINS(0.001)S(0.001)GPRPPVPPS(0.84)PAQPPPGVS(0.112)PS(0.046)R 76.133 9.154700000000001e-07 14203000.0 6309.1 13226.0 24876.0 36407.0 29643.0 27180.0 23093.0 30304.0 23726.0 21601.0 True False 8315.262562567723 17501.045851473395 24546.12798631034 28013.92863254288 25527.581125425513 25480.43030330468 25148.2322629312 25621.213116643597 24980.10792241098 20844.755564832692 0.39891389163595903 0.8395898813512359 1.1775685212506044 1.3439317407878526 1.2246524573544648 1.2223904580724785 1.206453689740499 1.2291443301867877 1.1983881434692891 1.0 14.347396834090986 -4.9120001058853 1.976137733936104 1.2187442165558762 0.27617206622084667 0.9052805854434913 0.08145819796994114 0.14521566816437878 0.7683408572031237 0.02149622564017901 0.22939452351487294 1.224615900691517e-05 4.9120001058853 -0.9425721503350295 down VSHYIINSSGPRPPVPPS(ph)PAQPPPGVSPSR ddPTM_PC-9_Lapatinib_30min_R1 1 VSHYIINSSGPRPPVPPSPAQPPPGVSPSR 30 1 I3L297;P46108-2;P46108 I3L297 CRK Adapter molecule crk 1 VSHYIINS(0.003)S(0.003)GPRPPVPPS(0.983)PAQPPPGVS(0.008)PS(0.002)R 85.17 5.238699999999999e-09 10353000.0 27331.0 24500.0 35930.0 21660.0 34302.0 27650.0 29560.0 29597.0 35635.0 27726.0 True False 26941.254928108443 24443.2717552755 32975.97409381085 23252.94865564185 32284.423800326753 26467.4739552981 31090.472161809157 30972.184669160597 31621.41104681427 32518.40215742726 0.8284925808371865 0.7516750557712324 1.0140711691235138 0.7150704558935665 0.9928047400371096 0.8139229543679435 0.9560885559903822 0.952451000489472 0.972415892199423 1.0 14.988968749625684 -6.820140703522416 0.3248505975958526 1.0140729726144293 0.7828894885580217 0.30471619578894604 0.0880426379336321 2.5225332715566133 0.5675149694218488 0.10652365482768743 0.21190760143056336 1.5130709615145256e-07 6.820140703522416 -0.23118348405640765 VSHYIINSSGPRPPVPPSPAQPPPGVS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 1 VSHYIINSSGPRPPVPPSPAQPPPGVSPSR 30 1 I3L297;P46108-2;P46108 I3L297 CRK Adapter molecule crk 1 VSHYIINSSGPRPPVPPS(0.008)PAQPPPGVS(0.827)PS(0.165)R 87.678 3.7264e-09 7220000.0 34686.0 33743.0 42830.0 32564.0 43883.0 40112.0 31034.0 33006.0 52167.0 29489.0 True False 34191.371279366635 33664.87015666375 39308.68272858108 34958.86519031951 41301.88821729747 38396.50326563898 32640.788669471764 34539.579254326985 46291.40311713657 34586.13435837741 0.9885860884330037 0.9733631925393098 1.1365445563030891 1.01077688613824 1.1941747461376349 1.1101704188094277 0.9437535959136629 0.998653937338934 1.3384381913708703 1.0 15.077906154357414 -5.246692795719 24.018119272988493 1.0876809488160035 0.9809746046866148 0.1399899819080851 0.10930347657854793 982.124540098237 1599598.6499210214 0.02751976260194895 0.0720239019763724 5.666399680217712e-06 5.246692795719 -0.10670634412938873 VSIGNIT(ph)LSPAISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSIGNITLSPAISR 14 0 Q0JRZ9-3;Q0JRZ9 Q0JRZ9-3 FCHO2 F-BAR domain only protein 2 1 VSIGNIT(0.889)LS(0.111)PAISR 167.18 0.00099225 34550000.0 21009.0 38809.0 45880.0 47194.0 42867.0 43852.0 49752.0 42384.0 43294.0 38310.0 True False 24565.40875333572 42661.70104025422 46973.95320086895 44549.87318501238 34467.5190733343 41552.32392296595 45039.130386712524 41271.464909560054 43927.09284579893 45255.299738206886 0.5428183858120891 0.9426896139688362 1.0379768440957002 0.9844122885656429 0.7616239263185128 0.9181758636742673 0.9952233362115629 0.9119697615153907 0.9706507989099316 1.0 15.46579913215004 -4.761446511955438 12.8845022040649 0.9430695422780919 0.5424807309300108 0.7387128951529056 0.07207485310275481 0.03011690023968244 407.1208819545534 0.018858189020602812 0.10531664214852586 1.7320223348259457e-05 4.761446511955438 -0.4005888113480811 VSIGNITLS(ph)PAISR ddPTM_PC-9_AZD4547_30min_R2 1 VSIGNITLSPAISR 14 0 Q0JRZ9-3;Q0JRZ9 Q0JRZ9-3 FCHO2 F-BAR domain only protein 2 1 VSIGNIT(0.007)LS(0.993)PAISR 112.03 0.00034291 43800000.0 43039.0 53259.0 69039.0 95615.0 86519.0 106230.0 92977.0 102820.0 67730.0 89407.0 True False 56724.5067331873 70473.93021349025 68123.49775071876 73572.43898702416 74507.33027664863 99587.42130684514 101251.77287968458 86931.53156854864 71310.06952646456 86276.88814337282 0.6574704762059093 0.8168344006146628 0.789591502622496 0.8527479440932464 0.8635838853255134 1.1542769268793422 1.1735677428632667 1.0075877032570757 0.8265257482161762 1.0 16.396686521496513 -6.583800945695606 4.961659616117307 1.041265781396446 0.7902652081610922 0.5851526860701828 0.10100744722367291 0.15690336138660552 7.791749753964611 0.0363191431445466 0.03660043650813541 2.6073483268319235e-07 6.583800945695606 -0.25100057323535385 VSIGNITLS(ph)PAISR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VSIGNITLSPAISR 14 0 Q0JRZ9-3;Q0JRZ9 Q0JRZ9-3 FCHO2 F-BAR domain only protein 2 1 VSIGNIT(0.419)LS(0.578)PAIS(0.003)R;VSIGNIT(0.001)LS(0.969)PAIS(0.03)R;VSIGNIT(0.001)LS(0.999)PAISR 148.36 2.9533000000000003e-05 37322900.0 25276.3 36776.2 51332.0 54295.0 51553.3 43061.7 50785.0 44394.0 40391.1 39695.399999999994 True False 29555.078360318872 40427.098090561376 52555.949557694075 51253.027176765 41451.80094346058 40803.46864620963 45974.2771484402 43228.70453933113 40981.743425046145 46891.861791386465 0.6302816145753425 0.8621346337327004 1.1207904218328146 1.09300473938912 0.8839871005308395 0.8701609850284253 0.980431899952524 0.9218807462081144 0.873962812723594 1.0 15.517049940414056 -4.844329768511686 3.6248821536374476 0.9650369325791033 0.6140458331438663 0.6018978167804749 0.08307387293738192 0.18160256836706812 4.000838535522284 0.0229634196615409 0.15402770681004052 1.4311008230447803e-05 4.844329768511686 -0.350991099435237 VSIGNITLS(ph)PAISR ddPTM_PC-9_Lapatinib_30min_R1 2 VSIGNITLSPAISR 14 0 Q0JRZ9-3;Q0JRZ9 Q0JRZ9-3 FCHO2 F-BAR domain only protein 2 1 VSIGNITLS(0.998)PAIS(0.001)R;VSIGNIT(0.004)LS(0.996)PAISR 193.41 1.643e-07 52551000.0 210868.0 210765.0 208770.0 213179.0 221694.0 197789.0 167294.0 205125.0 226284.0 163047.0 True False 207860.98365154467 210276.98659186315 191605.73647550514 228856.89480429742 208654.39478717383 189330.02553867822 175955.66474417126 214655.856345629 200797.51304384257 191229.45670352931 1.0869715745404218 1.0996056267516567 1.0019676872928587 1.1967659101761892 1.0911205751667177 0.9900672668447944 0.9201284560305077 1.1225041374165412 1.0500344272543063 1.0 17.544945245490013 -6.728178306200605 11.948987315712914 1.0181853740618254 1.0960148900543165 0.2705480371256569 0.0646122347108016 1.2276232916764451 437.7071504729946 0.022156650734011313 0.022080668632269873 1.8699142610226914e-07 6.728178306200605 0.0778295159924911 VSIGNITLSPAIS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 VSIGNITLSPAISR 14 0 Q0JRZ9-3;Q0JRZ9 Q0JRZ9-3 FCHO2 F-BAR domain only protein 2 1 VSIGNITLS(0.293)PAIS(0.707)R 167.18 0.00040581 42207000.0 36982.0 34535.0 59340.0 66853.0 68194.0 54889.0 67352.0 85342.0 50973.0 61982.0 True False 48741.50672661383 45697.7633812667 58553.11282793279 51441.07371855382 58726.440214123686 51456.782152983455 73346.19752188722 72154.35486406425 53667.32871655803 59812.02904585248 0.8149114401260007 0.7640229584292207 0.9789521232099551 0.8600456219119166 0.9818499915644632 0.8603082519326704 1.2262783706210554 1.2063518996947926 0.8972664792130047 1.0 15.868148039551238 -7.2427587537299125 24.6909473187111 1.0996701806108211 0.8802337044324456 0.46186435221488664 0.10814793380383668 601.4803394192412 795001.9686183416 0.041748300723120364 0.032279239071148005 5.71796175563722e-08 7.2427587537299125 -0.21943647617837547 VSISEGDDKIEYR ddPTM_PC-9_AZD4547_30min_R2 1 VSISEGDDKIEYR 13 1 M0R2U2;M0R1H0;M0R2B0;M0R0P1;M0R299;M0QXL5;M0R2Q4;P22087 M0R2U2 FBL rRNA 2-O-methyltransferase fibrillarin 0 99.539 0.0032164999999999997 6836200.0 21998.0 30812.0 28830.0 33957.0 29562.0 22746.0 26757.0 36472.0 24122.0 24822.0 False True 28992.906413175366 40771.37643849976 28447.695362812647 26128.7382804202 25457.826577263735 21323.689024244588 29138.321164822664 30836.090443183242 25397.039673960968 23952.989335228798 1.2104086887616203 1.7021414683525686 1.1876469765288657 1.0908341299176143 1.0628246111988078 0.8902308069282537 1.216479528171774 1.2873587514119225 1.0602868526563545 1.0 14.547918095218058 -5.459883313884727 7.400484903764713 1.0981657764521777 1.456327240817209 0.4831661441681975 0.15045826178455346 0.22500548900578785 23.208720719273828 0.039025857095446016 0.08121466232533847 3.468300241251917e-06 5.459883313884727 0.35816146436503127 VSISEGDDKIEYR ddPTM_PC-9_Lapatinib_30min_R1 1 VSISEGDDKIEYR 13 1 M0R2U2;M0R1H0;M0R2B0;M0R0P1;M0R299;M0QXL5;M0R2Q4;P22087 M0R2U2 FBL rRNA 2-O-methyltransferase fibrillarin 0 67.87899999999999 0.044217 7442800.0 45618.0 46454.0 44647.0 32552.0 31471.0 43521.0 37074.0 41311.0 47129.0 33463.0 False True 44967.478954683356 46346.43861712524 40976.29600240394 34945.98267028871 29619.937654366597 41659.70828240613 38993.51031552483 43230.45987322004 41820.83572962845 39247.03496335526 1.145754806615818 1.1808901910780942 1.0440609345562863 0.8904107712319562 0.7547051052906943 1.0614740278164596 0.9935402853217536 1.1014961999953392 1.065579495844115 1.0 15.260296044885099 -5.420197816559593 4.10643273349322 0.9788887347958759 1.1612092295822591 0.3663550877938754 0.09447136180479215 0.2634263757070402 7.632318869649473 0.0281989940496801 0.0618801886906453 3.8001626349033495e-06 5.420197816559593 0.18232049478638324 VSITEAMHR ddPTM_PC-9_Lapatinib_30min_R1 1 VSITEAMHR 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 78.939 0.011770000000000001 0.0 14515.0 9735.0 9623.5 10203.0 12897.0 12142.0 9094.5 10295.0 11266.0 9195.7 False True 14308.013438275006 9712.459205616615 8832.292977784273 10953.362656210233 12138.423816477585 11622.714964384435 9565.36871026974 10773.343283745256 9997.10444376062 10785.164492499962 1.326638406695127 0.9005388107312309 0.81892983495303 1.0155953266941118 1.125474147836937 1.077657644671707 0.886900586163663 0.9989039380194038 0.9269311052893665 1.0 13.396760559821969 -4.754061157561948 24.997501751071788 0.9742579853165366 1.3266390267835204 0.5978748417612649 0.08716031446629544 204.23406859058335 691889.0984567031 0.02380336041198378 0.2413134374668352 1.761727941550121e-05 4.754061157561948 0.3523810414669838 VSKPSQLQAHTPAS(ph)QQTPPLPPYASPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSKPSQLQAHTPASQQTPPLPPYASPR 27 1 Q96ST3 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 VSKPSQLQAHT(0.004)PAS(0.497)QQT(0.497)PPLPPY(0.001)AS(0.001)PR 58.802 0.0011012 9941300.0 16090.0 16295.0 19237.0 22248.0 18531.0 20878.0 20998.0 15054.0 19869.0 17937.0 True False 18813.71920801425 17912.659910096685 19695.683036728755 21001.516688989188 14899.983575896553 19783.120926381547 19008.917427644912 14658.848451031454 20159.546536544978 21188.836110786113 0.8879071559025926 0.8453819651273011 0.9295311424256439 0.9911595228346889 0.7031997179076656 0.933657744245377 0.8971194702840937 0.6918194267201591 0.9514230244238295 1.0 14.371016723120167 -4.3711734190427 17.89141683383514 0.8738132805442944 8.191834730184778 0.0 0.10294882705522346 2002.6943296924826 236749.42819709028 0.02392647859785085 1427.6712960588263 4.254285004628983e-05 4.3711734190427 7.318021449640484 VSKPSQLQAHTPASQQTPPLPPYAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 VSKPSQLQAHTPASQQTPPLPPYASPR 27 1 Q96ST3 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 VSKPSQLQAHTPAS(0.008)QQT(0.026)PPLPPY(0.136)AS(0.831)PR 66.67699999999999 0.00014493 7467200.0 30931.0 22965.0 30635.0 21603.0 27862.0 26440.0 23561.0 26494.0 32395.0 20479.0 True False 30489.918267949288 22911.825953465388 28116.30855451978 23191.75668549542 26223.21193879958 25309.22283465035 24780.87329514161 27725.007961102194 28746.33396552683 24018.76786344777 1.2694205814924187 0.9539134598295965 1.17059745588814 0.9655681264478636 1.0917800649843732 1.0537269429697274 1.0317295806357172 1.1543060043181754 1.1968280025418605 1.0 14.55187452381168 -7.7712564244425275 24.885241782029077 1.1316752564346608 1.0709921016254478 0.025275271468287674 0.09923905217053411 545.4082216195912 1382531.617775589 0.04923077882240157 0.02410202647175492 1.6933376924437853e-08 7.7712564244425275 -0.06068315480921305 VSKS(ph)PSPASTSTVPNMTDAPTAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSKSPSPASTSTVPNMTDAPTAPK 24 1 Q659A1 Q659A1 ICE2 Little elongation complex subunit 2 1 VS(0.134)KS(0.505)PS(0.168)PAS(0.115)T(0.032)S(0.046)T(0.001)VPNMTDAPTAPK 117.83 3.6738e-06 0.0 40518.0 37937.0 47128.0 53059.0 60725.0 51583.0 45468.0 45776.0 48685.0 36967.0 True False 47376.89713302186 41703.134643101424 48251.71025393531 50086.27624959895 48826.37216805991 48877.89667331826 41160.94188018665 44574.42850368112 49396.92602202895 43668.82446938904 1.0849134985584994 0.9549864268119806 1.1049463968914204 1.1469572826424128 1.1181059431147777 1.1192858353121156 0.9425704121950806 1.0207379989110283 1.1311714162733004 1.0 15.414316074967841 -7.22137727716658 24.99871857722566 1.0253479674170658 1.086935552471551 0.19184118195740907 0.06486470712852019 1005.5387975616839 627455.9897539319 0.026477306721016093 0.020508986118889162 6.006517169504932e-08 7.22137727716658 0.06158758505448514 VSKSPS(ph)PASTSTVPNMTDAPTAPK ddPTM_PC-9_AZD4547_30min_R2 1 VSKSPSPASTSTVPNMTDAPTAPK 24 1 Q659A1 Q659A1 ICE2 Little elongation complex subunit 2 1 VS(0.284)KS(0.284)PS(0.379)PAS(0.028)T(0.008)S(0.008)T(0.008)VPNMTDAPTAPK 85.814 9.873400000000001e-06 8998300.0 41249.0 40743.0 48870.0 67743.0 69224.0 54051.0 53237.0 60453.0 41319.0 53190.0 True False 54365.32396750026 53912.37797721009 48221.95186890923 52125.89796891673 59613.44249321783 50671.18242545699 57974.98986626543 51111.37792174154 43503.03798558966 51327.83428977599 1.0591782162593468 1.0503536477468116 0.9394893148358411 1.0155483606542837 1.1614252445693438 0.9872067100939461 1.1295039167045764 0.9957828657485835 0.8475525723526397 1.0 15.647453768768973 -8.006355730781761 24.351947171802347 0.923073401777685 1.0466938011674163 0.3426066352169026 0.06914674684146888 209.29139033038405 801892.4242820477 0.039198730409197365 0.017750868370542884 9.854719544844395e-09 8.006355730781761 0.12362039938973124 VSLDVNHFAPDELTVK ddPTM_PC-9_AZD4547_30min_R2 1 VSLDVNHFAPDELTVK 16 0 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 0 89.866 0.0030642 5285300.0 56635.0 49135.0 89822.0 127680.0 101930.0 76368.0 79630.0 94053.0 74192.0 82526.0 False True 74643.75191881934 65016.92786270562 88630.9015913477 98245.34863633562 87778.77893987202 71592.69688751923 86716.91573624969 79519.26997293033 78113.6376540301 79636.78985895927 0.9373023705628661 0.8164182405877214 1.1129391547338543 1.2336678664513354 1.102239041720951 0.8989902407456839 1.0889052144094418 0.998524301566687 0.9808737618928796 1.0 16.28114744706817 -5.262137487780133 24.99962666348042 1.056098051692475 0.8768603002773513 0.37361004539563336 0.0905963773082854 64.50188955948977 2309948.1207189304 0.025313767989630982 0.05820119650873533 5.468428174586735e-06 5.262137487780133 -0.17923775141512366 VSLDVNHFAPDELTVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSLDVNHFAPDELTVK 16 0 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 0 ; 96.666 0.0019254 14115200.0 116894.0 107903.0 126561.0 141181.0 155806.0 128932.0 126878.0 131124.0 115896.0 89426.0 False True 136681.84543826088 118614.89673391587 129578.69422526515 133271.08628497747 125276.9327627292 122170.57894818588 114859.19732282725 127682.13393736185 117590.75974630943 105638.22590417347 1.2938672934762052 1.1228406736167058 1.2266269441405477 1.2615801254166301 1.1859053073872179 1.1564997225437053 1.0872882078407708 1.2086735918225744 1.1131459160718804 1.0 16.688772452535495 -14.522878744409011 0.09917842047217992 0.3793428345268022 1.3154113791855933 0.6041708212967556 0.05259152086119701 135.43131250732816 0.9121156790021783 17.16342500597673 0.9211587313176128 3.0000000060189088e-15 14.522878744409011 0.9360685446587911 VSLDVNHFAPDELTVK ddPTM_PC-9_Lapatinib_30min_R1 1 VSLDVNHFAPDELTVK 16 0 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 0 69.069 0.018579 10777000.0 95709.0 104320.0 128400.0 111250.0 109150.0 123750.0 104970.0 89741.0 110880.0 105710.0 False True 94344.17210911881 104078.45344940187 117843.4476383334 119431.69611912088 102730.01159715651 118457.50097533966 110404.83297784548 93910.6944756274 98391.52678183716 123981.83265027894 0.7609515853442786 0.8394653573397369 0.950489641258487 0.9632999736018354 0.8285892328026124 0.955442409933381 0.8904920230471934 0.7574552857314625 0.7935963251920506 1.0 16.919769209036403 -9.99681542506623 12.535807980844117 0.9999993090457335 0.8648405713667007 0.23983432180618647 0.07433372842970426 0.0 0.0 0.07725026637629284 0.01873594163979741 1.0073597052497582e-10 9.99681542506623 -0.13515873767903286 VSLEDLYNGK ddPTM_PC-9_Lapatinib_30min_R1 2 VSLEDLYNGK 10 0 O60884;A0A087WT48 O60884 DNAJA2 DnaJ homolog subfamily A member 2 0 ; 137.95 0.00054486 4859600.0 24891.0 23224.2 29089.0 23796.0 26989.0 21733.5 25783.0 22122.0 21574.9 21760.1 False True 24536.04977554964 23170.425791790603 26697.414706787196 25546.037221128972 25401.56008241555 20804.008868262998 27117.91758281211 23149.868880331487 19144.907568231043 25521.30429148932 0.9613948211781544 0.9078856443680008 1.046083476058474 1.0009691091551265 0.9953080685960984 0.8151624474459397 1.0625600193895741 0.9070801639260795 0.7501539635110014 1.0 14.639414440892818 VSLEPHQGPGT(ph)PESK ddPTM_PC-9_AZD4547_30min_R2 3 VSLEPHQGPGTPESK 15 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 VSLEPHQGPGT(0.942)PES(0.058)K;VSLEPHQGPGT(0.972)PES(0.028)K;VSLEPHQGPGT(0.955)PES(0.045)K 133.9 1.7241e-05 214230000.0 49190.0 42533.0 137410.0 253074.0 190140.0 145806.0 111423.0 187324.0 131132.0 155326.0 True False 64831.39678443931 56280.96047185221 135587.85361790104 194731.6992543235 163742.34305530493 136688.7277705532 121339.43114504767 158377.38007728808 138063.369808716 149888.08401755465 0.4325320268744403 0.37548655612450604 0.9045939475883967 1.2991806555584287 1.0924306900615774 0.9119385884907598 0.8095335392427633 1.0566375647228847 0.9211097113800337 1.0 17.193526169182867 -5.315924066021191 4.520883583669904 1.0111828396956968 0.399514026519128 0.7865689144881343 0.12477734746022318 0.09014384046975678 3.923450116953218 0.03591562947576926 0.08196633899292279 4.831432695733257e-06 5.315924066021191 -0.6116688131765688 down VSLEPHQGPGT(ph)PESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 VSLEPHQGPGTPESK 15 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 VSLEPHQGPGT(0.993)PES(0.007)K;VSLEPHQGPGT(0.98)PES(0.02)K;VSLEPHQGPGT(0.957)PES(0.043)K;VSLEPHQGPGT(0.87)PES(0.13)K;VSLEPHQGPGT(0.997)PES(0.003)K;VSLEPHQGPGT(0.585)PES(0.415)K;VSLEPHQGPGT(0.998)PES(0.002)K 152.94 0.00037452 238304400.0 142478.5 176703.0 325129.0 399681.0 456367.0 374187.0 353271.0 338348.0 331645.0 258986.0 True False 166597.2959713524 194244.9060505564 332881.3084185983 377288.16935328604 366945.16240792105 354563.97500143375 319806.61341944756 329466.7235093388 336494.6807143019 305938.11166795203 0.5445457418269212 0.6349156860240376 1.0880674741821277 1.233217291223832 1.1994097773806704 1.1589401956767567 1.0453310693325701 1.076906442656361 1.0998782691040279 1.0 18.222880313563977 -5.242729755426201 3.9211836130672792 1.1251916468856888 0.5669448429139059 0.9089673050393601 0.06645865979057006 0.058201769061192295 2.0593018013729107 0.018739453714726302 0.05123875928844165 5.7183435627619385e-06 5.242729755426201 -0.558246803971783 VSLEPHQGPGT(ph)PESK ddPTM_PC-9_Lapatinib_30min_R1 5 VSLEPHQGPGTPESK 15 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 VSLEPHQGPGT(0.988)PES(0.012)K;VSLEPHQGPGT(0.997)PES(0.003)K;VSLEPHQGPGT(0.987)PES(0.013)K;VSLEPHQGPGT(0.89)PES(0.11)K;VSLEPHQGPGT(0.831)PES(0.169)K 124.45 7.1375e-05 288780000.0 210920.0 144367.0 338769.0 216041.0 306117.0 333839.0 211445.0 228756.0 353791.0 182140.0 True False 207912.2421220096 144032.72708138174 310916.7205061572 231929.37583164906 288111.7999091778 319561.48418671824 222392.58749166937 239384.8388748354 313943.3319956074 213622.65631370546 0.9732686865230713 0.6742390042649282 1.4554482463207232 1.0856965259858025 1.3486949599862892 1.4959156940612204 1.0410533757481475 1.1205966773641187 1.4696162729789333 1.0 17.704705138400755 -5.257326399578061 24.99917847654253 1.2551079474795772 0.8237538328227836 0.4524040579964076 0.18849386080104172 292.41591427105925 1777321.10016982 0.046751794287815965 0.1146478327235832 5.52934388096556e-06 5.257326399578061 -0.43135411465679363 VSLEPHQGPGTPES(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 VSLEPHQGPGTPESK 15 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 VSLEPHQGPGT(0.33)PES(0.67)K 89.04899999999999 0.0026388 123700000.0 31686.0 28513.0 64194.0 101900.0 88858.0 65073.0 52407.0 71812.0 49163.0 75851.0 True False 41761.48889025704 37729.2696478951 63342.745616385546 78408.52933930609 76521.60050072717 61003.975023066385 57071.121474188505 60715.1054755943 51761.65581174627 73195.47957724771 0.5705473771257085 0.5154590128489707 0.8653914966092412 1.0712209250102218 1.045441616650236 0.8334391054666856 0.7797082798529632 0.8294925564565486 0.7071701163883898 1.0 16.159466932527835 -5.282550641089281 6.985990369651314 0.8918547199401312 0.5422751797765237 0.6114445206964996 0.11115099656850809 0.11360939928760325 26.31879485407985 0.032202882367786935 0.0711338363616321 5.2173426365038254e-06 5.282550641089281 -0.3495795401636075 VSLEPHQGPGTPES(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSLEPHQGPGTPESK 15 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 VSLEPHQGPGT(0.492)PES(0.508)K 94.325 0.0017312 60832000.0 28447.0 25889.0 70043.0 79037.0 84420.0 87069.0 56655.0 64709.0 65422.0 67521.0 True False 33262.515246139315 28459.08882555958 71713.09075955662 74608.81313141136 67878.50701404049 82502.94836378546 51288.228253320405 63010.457314852836 66378.67298373574 79762.02280405826 0.41702196204140063 0.3567999885794219 0.8990881655010872 0.9353926907632951 0.8510128583472542 1.0343637919823134 0.6430156414076159 0.7899806837853527 0.8322089968405167 1.0 16.283414377204046 -5.261121400416377 24.99992114415163 0.8646055137134994 0.38691093390191245 0.7727485551553589 0.10538880869952662 12.336224184948682 969787.809992079 0.02790030716333075 0.06511451597111322 5.4812372385423585e-06 5.261121400416377 -0.4776945798115869 VSLLGPVT(ph)TPEHQLLK ddPTM_PC-9_AZD4547_30min_R2 2 VSLLGPVTTPEHQLLK 16 0 Q9H0H5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 VSLLGPVT(0.982)T(0.018)PEHQLLK;VS(0.012)LLGPVT(0.806)T(0.183)PEHQLLK 210.2 4.7092e-17 30077000.0 77252.0 83633.0 129041.0 158041.0 142575.0 106199.0 90782.0 134481.0 96536.0 126808.0 True False 101816.52905857889 110665.73171754685 127329.83202610827 121607.08915910963 122780.92227364086 99558.35974174601 98861.42213196297 113700.05151594998 101638.69587785006 122368.49051735154 0.8320485823443378 0.9043646060327493 1.0405442731848786 0.9937777988841503 1.0033704081381214 0.813594736037288 0.8078993351474305 0.9291611838574375 0.8305953227676527 1.0 16.900872591073814 -6.75780323196404 24.999921222217914 0.8675507658548047 0.9589446482606343 0.2048701279228834 0.07622401313120762 140.04281621337952 962849.8391095153 0.026397384147447637 0.025420871458731557 1.7466133207636996e-07 6.75780323196404 0.09139388240582957 VSLLGPVT(ph)TPEHQLLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSLLGPVTTPEHQLLK 16 0 Q9H0H5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 VSLLGPVT(0.5)T(0.5)PEHQLLK;VSLLGPVT(0.626)T(0.374)PEHQLLK 118.96 0.00024494 15165700.0 45196.0 40338.0 54606.0 67219.0 75111.0 70400.0 68452.0 58370.0 54299.0 44912.0 True False 52846.7901383103 44342.49005544525 55908.01413440819 63452.937356938426 60393.538738825 66708.10006788305 61967.73101043667 56837.84934812712 55093.020151384415 53054.19007680365 0.9960907906012115 0.8357961923695951 1.0537907383653058 1.196002375402981 1.1383368335544577 1.257357806637202 1.1680082368749645 1.0713168793236891 1.0384291998733608 1.0 15.695179075351323 -5.47697189250043 5.183616277918707 1.1348653673304012 0.9188440407932897 0.5098434521275181 0.08026174956655344 0.14907214932857912 9.362527557487835 0.021720054473817526 0.044918236068141965 3.334479927888189e-06 5.47697189250043 -0.21602132653711148 VSLLGPVT(ph)TPEHQLLK ddPTM_PC-9_Lapatinib_30min_R1 2 VSLLGPVTTPEHQLLK 16 0 Q9H0H5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 VS(0.001)LLGPVT(0.666)T(0.334)PEHQLLK;VSLLGPVT(0.68)T(0.32)PEHQLLK 156.17 8.614899999999999e-05 18422900.0 73188.0 67160.0 62845.0 56072.0 65882.0 67590.0 56840.0 59303.0 64691.0 54521.0 True False 72144.32569896444 67004.49514629823 57678.126688715354 60195.721930708634 62006.95028899563 64699.33325998549 59782.897079744 62058.43387624525 57404.81835356992 63944.882205334 1.1282267354453972 1.0478476593504307 0.9019975438144462 0.9413688766743459 0.9696937135623229 1.0117984587449684 0.9349129284150464 0.970498837998776 0.89772342013606 1.0 15.964541277945791 -5.0140321633363625 3.8331097252302597 0.9542630841250154 1.1193414392371577 0.7144255660860297 0.03567218354998447 0.10898070807125611 3.5161943047506763 0.009190430528387498 0.036452032264402544 9.68206149402192e-06 5.0140321633363625 0.1650783551121423 VSLPS(ph)SPVPASPASSSGADQR ddPTM_PC-9_AZD4547_30min_R2 1 VSLPSSPVPASPASSSGADQR 21 0 Q5T6S3-2 Q5T6S3-2 1 VSLPS(0.82)S(0.18)PVPASPASSSGADQR 241.11 1.2519999999999997e-125 0.0 9856.2 7996.0 15121.0 14858.0 13198.0 12127.0 12600.0 13563.0 10460.0 14461.0 True False 12990.266578304352 10580.550629697656 14920.485660114113 11432.71765381169 11365.685514062878 11368.696772927731 13721.375590565674 11467.149996734326 11012.894245486768 13954.724791585828 0.9308866188559299 0.7582056104809268 1.0692067298317915 0.819272169430757 0.8144686250577982 0.8146844128221451 0.9832781223202013 0.821739602034186 0.7891874909727441 1.0 13.768466052091771 VSLQVHPDR ddPTM_PC-9_AZD4547_30min_R2 2 VSLQVHPDR 9 0 Q8WXX5 Q8WXX5 DNAJC9 DnaJ homolog subfamily C member 9 0 ; 112.85 0.0017968 4147700.0 29998.0 25965.0 55004.0 74800.0 66247.0 54539.0 38481.0 64376.0 46486.0 56847.0 False True 39536.74000283819 34357.67847675084 54274.611021024844 57556.01564847993 57049.74755645732 51128.66770831251 41905.734452425226 54428.16841331335 48943.15505695007 54856.80383288013 0.7207262771503399 0.6263157179448633 0.989387044611113 1.0492046861465514 1.0399757836832408 0.9320387652199846 0.7639113386935555 0.9921862852077091 0.8921984446278379 1.0 15.743382947255489 -5.263081872295685 24.996905774078577 0.955500858643157 0.6735209819645003 0.6609483156025601 0.08130903245559863 85.13108256359045 1295623.3867177018 0.022788840657686757 0.05179297739826778 5.456549856475782e-06 5.263081872295685 -0.28197987667865676 VSLQVHPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSLQVHPDR 9 0 Q8WXX5 Q8WXX5 DNAJC9 DnaJ homolog subfamily C member 9 0 64.10300000000001 0.045936000000000005 1526400.0 6737.7 4698.4 9725.4 8768.4 9835.8 8996.0 7750.2 11665.0 10333.0 7330.8 False True 7878.259534359081 5164.826101356135 9957.290419784886 8277.134975536354 7908.545596881087 8524.23392344709 7016.044949411064 11358.806110089146 10484.100576884559 8659.816009419126 0.9097490669305259 0.5964129140548075 1.1498270181438635 0.9558095652994778 0.9132463770915114 0.9843435373425293 0.8101840664720634 1.311668296154835 1.2106608922731374 1.0 13.080120657752836 -7.759051081900016 24.999570702792457 1.1958734618869435 0.9060906470660192 0.4047268717669811 0.1500531642310924 58.317896649125906 610465.6670686117 0.07412573303313581 0.04018886665957766 1.741602013381093e-08 7.759051081900016 -0.2897828148209244 VSLQVHPDR ddPTM_PC-9_Lapatinib_30min_R1 1 VSLQVHPDR 9 0 Q8WXX5 Q8WXX5 DNAJC9 DnaJ homolog subfamily C member 9 0 88.056 0.008739299999999998 3207000.0 20638.0 20185.0 26305.0 19778.0 26410.0 23019.0 18535.0 20657.0 28894.0 16224.0 False True 20343.698335454334 20138.262872662715 24142.304440236418 21232.540097473877 24856.615724057763 22034.531029909856 19494.651607548487 21616.799632086037 25639.65345269124 19028.296782878886 1.0691287069770221 1.0583323931957245 1.2687580352414394 1.1158402845901745 1.3062974583423057 1.1579875635393648 1.0245084901707657 1.1360343954450096 1.3474486836762534 1.0 14.215858811741334 -5.2173229001767645 24.49854843012342 1.1718319098191912 1.0637303974706107 0.13546959659575253 0.1068708475063956 713.224904655315 396061.19949250924 0.026685500650535404 0.07060228477146711 6.062853856730808e-06 5.2173229001767645 -0.10810151234858045 VSMPDVELNLKS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 VSMPDVELNLKSPK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VSMPDVELNLKS(1)PK;VSMPDVELNLKS(1)PK;VSMPDVELNLKS(1)PK 113.11 0.00052219 193335000.0 183774.0 203314.0 158787.0 217599.0 193969.0 194224.0 269968.0 285692.0 287253.0 246564.0 True False 242210.3092633373 269031.2744780329 156681.38063041744 167434.9124210371 167039.75249865613 182079.1425764915 293994.62900268455 241544.86594905384 302436.607141378 237931.86940824127 1.0179817855663342 1.1307071858307116 0.6585136367822378 0.7037094813631454 0.7020486701260304 0.7652574790814668 1.2356252642148216 1.0151850046393467 1.2711059173937733 1.0 17.86018899864994 -7.256297007238428 24.917677387495406 1.1317444665807077 0.8240742521450065 0.4615865581086458 0.15906826036698393 405.6970824089723 1965835.4121260112 0.06727606730172855 0.05048349533096418 5.5424654273203996e-08 7.256297007238428 -0.3076702144357012 VSMPDVELNLKS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 VSMPDVELNLKSPK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VSMPDVELNLKS(1)PK;VSMPDVELNLKS(1)PK;VSMPDVELNLKS(1)PK 91.616 0.0021086 65274100.0 205390.0 163782.0 145021.0 180528.0 230436.0 189045.0 236738.0 190833.0 242320.0 285267.0 True False 202461.1009360868 163402.77284173627 133097.9331772486 193804.6313437536 216882.20753460712 180959.9860354188 248995.13527206946 199699.79785011717 215027.36985727638 334575.0208556157 0.6051291588305929 0.4883890387987213 0.3978119252204617 0.579256128709588 0.6482319181508821 0.5408652013908453 0.7442131652127197 0.5968759931312885 0.6426880563509565 1.0 18.351970213199344 -14.522878745250262 0.14252311894886582 2.49897375290877 0.4322930137165518 0.7523103281300997 0.07650737636253821 67.95985559421163 0.5867712816430636 28.71262261593605 0.46005066181638876 3.0000000002077554e-15 14.522878745250262 -2.066680739192218 VSNGS(ph)PSLER ddPTM_PC-9_AZD4547_30min_R2 2 VSNGSPSLER 10 0 P46527;E7ES52 P46527 CDKN1B Cyclin-dependent kinase inhibitor 1B 1 VS(0.003)NGS(0.995)PS(0.001)LER;VS(0.057)NGS(0.886)PS(0.057)LER 101.32 0.0051354 27613000.0 28169.0 29132.0 39490.0 48883.0 43792.0 42042.0 39887.0 39644.0 42993.0 39474.0 True False 37126.15604840153 38548.34929269037 38966.336797692384 37613.77958482141 37712.236704943316 39413.10709387548 43436.8657286423 33517.93072849191 45265.52220805092 38092.02727495048 0.9746437431755145 1.0119794626430916 1.0229525595062474 0.9874449399430214 0.9900296571966146 1.0346812683239295 1.1403138356252993 0.8799198448157545 1.1883201143725362 1.0 15.21720145037767 -6.872473884270181 5.576394109745929 1.0480539340712012 0.9992926708880353 0.09964588548477238 0.07769248054430405 0.558234368763263 25.244454535310677 0.02590704822756448 0.02286857000248069 1.341300590334437e-07 6.872473884270181 -0.04876126318316587 VSNGS(ph)PSLER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSNGSPSLER 10 0 P46527;E7ES52 P46527 CDKN1B Cyclin-dependent kinase inhibitor 1B 1 VS(0.031)NGS(0.941)PS(0.029)LER;VS(0.042)NGS(0.956)PS(0.002)LER 105.95 0.0023864 32808000.0 42104.0 59577.0 67035.0 65670.0 64637.0 63903.0 46074.0 43011.0 50355.0 36037.0 True False 49231.375608094 65491.41082932373 68633.36863165337 61990.722805012636 51971.84385058691 60551.81418519778 41709.53717312656 41882.0068239215 51091.34661269933 42570.222831264975 1.1564744634584543 1.5384324176293642 1.612238885938994 1.4561991618114014 1.2208497018347078 1.4223983375705171 0.9797819790244016 0.9838333942936747 1.2001662949994276 1.0 15.37755702138905 -7.2568423527936 24.883037963503945 1.0395981931919216 1.411249971241158 0.6156985982710319 0.13925419016878465 252.8967610543149 1368897.9957641268 0.056902076262956076 0.04257270017888438 5.535510096122407e-08 7.2568423527936 0.3716517780492363 VSNGS(ph)PSLER ddPTM_PC-9_Lapatinib_30min_R1 2 VSNGSPSLER 10 0 P46527;E7ES52 P46527 CDKN1B Cyclin-dependent kinase inhibitor 1B 1 VS(0.003)NGS(0.995)PS(0.002)LER;VS(0.137)NGS(0.861)PS(0.002)LER 120.84 0.0011039 20012000.0 61792.0 52907.0 54724.0 54789.0 56293.0 65936.0 48987.0 64517.0 71434.0 50671.0 True False 60910.83474873504 52784.497092096375 50224.803960748846 58818.36583074615 52981.95641629621 63116.07098432315 51523.30716476813 67514.69535088811 63388.350686631995 59429.41483513658 1.0249273851628538 0.8881880671133326 0.8451169189546576 0.9897180713273799 0.8915106528185363 1.0620341990479587 0.8669664223970432 1.1360484625026335 1.0666157636328393 1.0 15.858889555237988 -7.764147167036635 24.99999972141381 1.075999088291101 0.9377674246738051 0.3948199711919673 0.07307703757326563 67.11150658188976 619590.5258801256 0.03650226748787396 0.018776228505781086 1.7212851934867603e-08 7.764147167036635 -0.13823166361729589 VSNLQVS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 4 VSNLQVSPK 9 0 O00443;A0A0C4DGF9;O00443-2 O00443 PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 1 VSNLQVS(1)PK;VSNLQVS(1)PK;VSNLQVS(1)PK;VSNLQVS(1)PK 117.2 0.0018725000000000002 116882000.0 618705.0 502722.0 512065.0 665250.0 615960.0 573505.0 537171.0 518341.0 523675.0 526853.0 True False 815440.3201365409 665217.0552354763 505274.6835226721 511886.8905100432 530444.5862435346 537643.6416886213 584978.1783618847 438243.30874122697 551355.3913962992 508408.03683157306 1.6039091852646743 1.3084314311416982 0.9938369319878808 1.0068426410018034 1.0433442192403064 1.0575042146053515 1.1506076536624026 0.8619913081476513 1.084474185011662 1.0 18.95562731084855 -4.951422902036564 2.338887908263069 1.0248557563052176 1.646757379180388 0.8666427649509865 0.07216853557018768 0.1317348799274706 1.145491196467159 0.019098914445505766 0.14614523948823618 1.1183483413286785e-05 4.951422902036564 0.6219016228751704 VSNLQVS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSNLQVSPK 9 0 O00443;A0A0C4DGF9;O00443-2 O00443 PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 1 VSNLQVS(1)PK 93.62299999999999 0.0061133 14010000.0 76550.0 84974.0 68488.0 73801.0 99389.0 81358.0 108180.0 119790.0 86216.0 83350.0 True False 89508.40306858261 93409.65714639805 70121.0136621864 69666.16923607019 79914.43891990621 77091.44325742638 97932.40724462456 116645.63942799631 87476.74589535283 98460.69520176313 0.9090775043296647 0.9486999553982975 0.7121726443074184 0.7075530910411719 0.8116379714377153 0.7829666761894436 0.994634529483506 1.1846924215695316 0.8884433094454364 1.0 16.58726030559994 -7.332479260502333 4.907912948919685 1.0372120457022789 0.8089317665249347 0.5111510102847411 0.09789762137461272 0.17995601556879884 8.266822714471935 0.04365614986917555 0.02913474652741582 4.6507258492561885e-08 7.332479260502333 -0.22828027917734417 VSNLQVS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 VSNLQVSPK 9 0 O00443;A0A0C4DGF9;O00443-2 O00443 PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 1 VSNLQVS(1)PK;VSNLQVS(1)PK;VSNLQVS(1)PK 128.36 0.0013325 84783000.0 346581.0 303398.0 242172.0 284521.0 324259.0 323275.0 358830.0 315972.0 333390.0 294125.0 True False 341638.69138482877 302695.50057171687 222261.55297095396 305445.6234742325 305186.7231377222 309449.2818408316 377408.46163132525 330653.21263249696 295840.10744766105 344964.1143530727 0.9903600901372589 0.8774695337205606 0.6443034035229184 0.8854417336917753 0.8846912198680522 0.8970477477669128 1.0940513691955958 0.958514810308853 0.8575967619196095 1.0 18.39608676462438 -6.83977472980105 2.4802429881375536 0.9748102566211487 0.8432556563526874 0.2437871811837502 0.09783951813727552 0.4174173170859552 5.2410970249252475 0.040114017520396755 0.03537733805822088 1.446189720334609e-07 6.83977472980105 -0.13155460026846133 VSNQDSKS(ph)PLGFYCDQNPVESSMCQSNSR ddPTM_PC-9_AZD4547_30min_R2 1 VSNQDSKSPLGFYCDQNPVESSMCQSNSR 29 1 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 VS(0.002)NQDS(0.078)KS(0.747)PLGFY(0.172)CDQNPVESSMCQSNSR 73.51899999999999 2.7611e-05 28190000.0 56121.0 47483.0 64760.0 99028.0 91109.0 76310.0 60342.0 82491.0 68677.0 79587.0 True False 73966.3106106835 62830.95116932643 63901.2400865677 76198.62456734845 78460.08800581565 71538.32363668788 65712.32110205661 69743.91140460166 72307.12601312567 76800.68335439729 0.9630944332795249 0.8181040639885008 0.8320399935986894 0.9921607626292772 1.0216066391461782 0.9314803008532332 0.8556215678293726 0.9081157661419221 0.9414906593924943 1.0 16.228831527313773 VSNQDSKS(ph)PLGFYCDQNPVESSMCQSNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSNQDSKSPLGFYCDQNPVESSMCQSNSR 29 1 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 VS(0.037)NQDS(0.206)KS(0.756)PLGFY(0.001)CDQNPVESSMCQSNSR 70.771 0.00012833 26310000.0 54153.0 40872.0 56092.0 87287.0 70248.0 66722.0 64898.0 67858.0 68837.0 47355.0 True False 63320.033329496335 44929.50204636219 57429.44601009461 82396.59237827217 56483.40867948744 63222.98086263189 58750.391619168484 66076.79940149424 69843.61089819044 55940.08663802626 1.1319259074306371 0.8031718352009232 1.026624187797663 1.47294359609128 1.0097125706110694 1.1301909714893963 1.050237765974997 1.1812065974988564 1.2485431306199124 1.0 15.771594867760301 -5.533481098879626 24.992201185611464 1.1595930571061943 0.9543860697345353 0.21794654353133436 0.1488996729780937 263.54352170306885 621231.1081069817 0.039033455301741495 0.06769373380848066 2.927648284060149e-06 5.533481098879626 -0.205206987371659 VSNQDSKS(ph)PLGFYCDQNPVESSMCQSNSR ddPTM_PC-9_Lapatinib_30min_R1 1 VSNQDSKSPLGFYCDQNPVESSMCQSNSR 29 1 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 VS(0.104)NQDS(0.199)KS(0.584)PLGFY(0.111)CDQNPVES(0.001)SMCQSNSR 51.463 0.015501 26712000.0 95431.0 66232.0 84731.0 73428.0 93170.0 83302.0 67287.0 67697.0 102750.0 68449.0 True False 94070.13644009815 66078.64387328184 77764.74425111845 78828.14006862724 87689.92377926764 79739.36764644632 70770.79162218038 70842.44976004882 91177.21299453247 80280.31844744067 1.1717708432071758 0.8230989257540546 0.9686651193596203 0.981911153232854 1.092296660939107 0.993261725769704 0.8815459752880008 0.8824385743615255 1.1357355670459375 1.0 16.29275871899079 -4.728157446440421 24.691548618459233 0.9711556482133233 1.1717725603052285 0.304313481667877 0.09001426044162059 5664.212865884835 4201939.3194564525 0.022542663971839592 3.9556949720386596 1.87000407772874e-05 4.728157446440421 0.20061691209190513 VSNQDSKSPLGFY(ph)CDQNPVESSMCQSNSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSNQDSKSPLGFYCDQNPVESSMCQSNSR 29 1 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 VS(0.017)NQDS(0.173)KS(0.377)PLGFY(0.432)CDQNPVES(0.001)SMCQSNSR 47.979 0.013659000000000001 25302000.0 33123.0 38847.0 41817.0 58032.0 68524.0 54376.0 49892.0 59423.0 56713.0 48636.0 True False 38730.06969092956 42703.47342912094 42814.07587185561 54780.655182282484 55097.214103649814 51524.42683652282 45165.86857320033 57863.20921387284 57542.320334545075 57453.32179763586 0.674113671396512 0.743272487873419 0.7451975713894643 0.9534810776517477 0.9589909230612494 0.8968050101263769 0.786131544008633 1.0071342683662523 1.0015490581592947 1.0 15.810102687606795 -3.6208227657803564 0.36815309220643355 0.9758140011909446 1.8713391970514448e-11 0.6767674808176569 0.06851129224708453 9.434336441854333 0.5216365320655946 0.06303272913736409 4.835812556174835 0.00023942926604017458 3.6208227657803564 -0.9758140011722313 VSNS(ph)PEPQK ddPTM_PC-9_AZD4547_30min_R2 2 VSNSPEPQK 9 0 O60271;O60271-3;D6RHI8 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 VS(0.01)NS(0.99)PEPQK;VS(0.315)NS(0.685)PEPQK 91.961 0.012121 7194000.0 59660.0 57771.0 76206.0 72686.0 64108.0 85787.0 72193.0 83304.0 74486.0 79320.0 True False 78630.63899491065 76444.34597652112 75195.45864788412 55929.36568750543 55207.71078462977 80422.7253285358 78618.0371436275 70431.28093548301 78423.17789381718 76543.0309431288 1.0272736528206328 0.9987107256481519 0.9823945788579247 0.7306918082334726 0.7212637140754056 1.0506864483624851 1.0271090153464189 0.9201527567913165 1.024563267583241 1.0 16.223983409377972 VSNS(ph)PEPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSNSPEPQK 9 0 O60271;O60271-3;D6RHI8 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 VS(0.002)NS(0.998)PEPQK 78.548 0.021440999999999998 4612400.0 38365.0 44563.0 40539.0 41292.0 42376.0 33643.0 41181.0 33618.0 34405.0 30042.0 True False 44859.4367567102 48986.92013339301 41505.603505013634 38978.54311047025 34072.7269986613 31878.70185488336 37280.03755537886 32735.563121215313 34908.10803713476 35488.376787658846 1.2640599773024885 1.3803651946805386 1.1695548588586697 1.0983467444480335 0.9601094804231836 0.8982857132527189 1.0504858471955547 0.9224305557023721 0.9836490478559765 1.0 15.115058967643709 -5.738544040107553 1.6417118642882054 0.9661972266653229 1.3243670044793143 0.8716112265708809 0.05323122863734409 0.11561259947418398 0.6307599463601425 0.01624495700457904 0.03625315449719763 1.82581159126312e-06 5.738544040107553 0.3581697778139914 VSNS(ph)PEPQK ddPTM_PC-9_Lapatinib_30min_R1 4 VSNSPEPQK 9 0 O60271;O60271-3;D6RHI8 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 VSNS(1)PEPQK;VS(0.011)NS(0.989)PEPQK;VS(0.018)NS(0.982)PEPQK;VS(0.017)NS(0.983)PEPQK 101.71 0.0040401 29316700.0 136002.0 184323.0 176646.0 161303.0 198879.0 186383.0 185682.0 185913.0 181416.0 152653.0 True False 134062.5865402875 183896.21141827136 162122.84775327903 173165.76071103377 187181.328231158 178411.8335699936 195295.7054109962 194551.19668877407 160983.01968482847 179038.86765266306 0.7487904067868105 1.0271301077206967 0.9055176112250595 0.9671964695787556 1.0454787314355192 0.9964977767627201 1.090800606435199 1.0866422427682298 0.8991512390322804 1.0 17.449913291438747 -4.282227364873682 1.9294398831754596 1.0074461541413082 3.8480405314692355e-20 0.5718756507689815 0.06425219576049081 3.9075446420523994 3.9909196996769483 0.017625852896479353 11.464727010873856 5.2212277208258424e-05 4.282227364873682 -1.0074461541413082 VSNS(ph)PEPQKAVEQEDELSDVSQGGSK ddPTM_PC-9_AZD4547_30min_R2 2 VSNSPEPQKAVEQEDELSDVSQGGSK 26 1 O60271;O60271-3;D6RHI8 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 VS(0.205)NS(0.795)PEPQKAVEQEDELSDVSQGGSK;VS(0.088)NS(0.912)PEPQKAVEQEDELSDVSQGGSK 103.51 5.8434e-10 16024200.0 40556.0 29077.6 40139.0 75392.0 75899.0 46062.0 37925.3 42584.0 29975.6 53279.0 True False 53451.96438279569 38476.36555654034 39606.73063364331 58011.539194788755 65361.7339621047 43181.7358583819 41300.57822895875 36003.62128297091 31560.04901959973 51413.71842686549 1.0396440097759034 0.7483676873376089 0.7703533579268873 1.1283280215825757 1.2712897639387795 0.8398874304298114 0.803298798310175 0.7002726584381367 0.6138449033693795 1.0 15.649865736356654 -6.989100018844637 24.87502494419875 0.7639790852463565 0.9816087435343275 0.2583763696660085 0.17078953537249594 305.9879595711681 698296.6941231444 0.06532986931613628 0.05756279250768331 1.0254157438610277e-07 6.989100018844637 0.21762965828797098 VSNS(ph)PEPQKAVEQEDELSDVSQGGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSNSPEPQKAVEQEDELSDVSQGGSK 26 1 O60271;O60271-3;D6RHI8 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 VS(0.276)NS(0.719)PEPQKAVEQEDELS(0.004)DVSQGGSK 55.417 0.0022841999999999997 5070000.0 8078.9 4049.5 4318.4 10138.0 8541.9 10709.0 7626.1 14042.0 11552.0 9177.9 True False 9446.498204451615 4451.507597786842 4421.367033623201 9570.000727839464 6868.176013542215 10147.401187882935 6903.700599817262 13673.41237872883 11720.926145763127 10841.780617783574 0.8713050501092687 0.4105882377369927 0.4078081995471218 0.8826964006393901 0.6334915135873965 0.9359533775511321 0.6367681512106276 1.261177740149121 1.081088666057078 1.0 13.40431409910855 -7.2157167195944085 0.836558550593103 1.1163591877358514 0.5957559175734118 0.4554017320963114 0.19808203000982585 0.5375210430936047 0.7421735196881184 0.15445669275725749 0.09535268810425519 6.085318032967166e-08 7.2157167195944085 -0.5206032701624396 VSNS(ph)PEPQKAVEQEDELSDVSQGGSK ddPTM_PC-9_Lapatinib_30min_R1 1 VSNSPEPQKAVEQEDELSDVSQGGSK 26 1 O60271;O60271-3;D6RHI8 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 VS(0.315)NS(0.685)PEPQKAVEQEDELSDVSQGGSK 107.95 0.00012837 0.0 40348.0 16110.0 20512.0 19776.0 12446.0 14564.0 10950.0 10545.0 18128.0 13276.0 True False 39772.63012108301 16072.69828479544 18825.582538609753 21230.39301080208 11713.95074977747 13941.131670342202 11516.93742123852 11034.959196415135 16086.233743697181 15570.738910841967 2.5543187352135983 1.0322373508943725 1.2090359132219104 1.3634801233497835 0.7523053862023851 0.8953416886744493 0.7396525937005617 0.7086984927048934 1.0331066390494978 1.0 13.926549788816294 -2.7943054146713955 1.2089404766384857 0.9171135260268908 199.99999792974927 0.8351841458325133 0.2091012320776733 74.5970090899792 1.1627811682445388 0.0652804701309541 40139.19420199372 0.001605811579656304 2.7943054146713955 199.08288440372237 up VSNS(ph)PPLGR ddPTM_PC-9_AZD4547_30min_R2 2 VSNSPPLGR 9 0 H0Y9Y2 H0Y9Y2 BOD1L1 1 VSNS(1)PPLGR;VS(0.003)NS(0.997)PPLGR 104.07 0.0027276999999999996 34419000.0 65374.0 43502.0 83714.0 108833.0 102459.0 83762.0 59567.0 103744.0 78097.0 86363.0 True False 86161.5721363272 57563.170772024445 82603.89766224417 83743.2333030884 88234.33642107664 78524.34889865367 64868.34760343056 87712.74859995628 82225.04798181463 83339.45765685126 1.0338628851065477 0.690707287885647 0.9911739287093067 1.004844951690227 1.0587342286816883 0.9422229410464403 0.7783629678816105 1.0524756347840896 0.9866280666281128 1.0 16.346712091081187 VSNS(ph)PPLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VSNSPPLGR 9 0 H0Y9Y2 H0Y9Y2 BOD1L1 1 VS(0.016)NS(0.984)PPLGR;VS(0.021)NS(0.979)PPLGR;VS(0.002)NS(0.998)PPLGR 108.31 0.0024439 33369800.0 61459.0 74788.0 101050.0 91625.0 106336.0 81338.0 103851.0 91184.0 96051.0 70540.0 True False 71862.79482941871 82212.45838332699 103459.41523425913 86491.5483022581 85500.22413936316 77072.4920926344 94013.48146387041 88790.51661743414 97455.56416436075 83328.34360566724 0.8624051759566148 0.9866085754971811 1.2415873250026148 1.0379607293235065 1.0260641270391004 0.9249252866151132 1.128229332251799 1.0655500010610486 1.1695367980137399 1.0 16.34651968215241 -7.319566325292289 24.999513472003688 1.0962915420802786 1.024129970327025 0.11826672155444273 0.10074179720409852 699.0714587304205 300657.6052629551 0.04403912502003824 0.029691181999558287 4.7910827808212004e-08 7.319566325292289 -0.07216157175325355 VSNS(ph)PPLGR ddPTM_PC-9_Lapatinib_30min_R1 1 VSNSPPLGR 9 0 H0Y9Y2 H0Y9Y2 BOD1L1 1 VS(0.02)NS(0.98)PPLGR 77.67399999999999 0.022713999999999998 15677000.0 24037.0 32831.0 33637.0 20208.0 19162.0 19233.0 23008.0 21102.0 31218.0 18559.0 True False 23694.22797215407 32754.98183663061 30871.495702574877 21694.16373191185 18034.92883394148 18410.449424312785 24199.241660991378 22082.475956638405 27701.9000998863 21766.89842168695 1.0885440595683062 1.5048070332333583 1.4182771979960531 0.9966584724949773 0.8285483987912946 0.8458003096100248 1.1117450539889973 1.0144980478540313 1.2726617988112696 1.0 14.409848231244954 -5.767452637250445 24.97920999486784 1.0004302882343281 1.353969211420383 0.4846690607142994 0.15411204255261743 112.85612078164249 468808.8754352023 0.0446456755230342 0.06820061305527723 1.70823400436944e-06 5.767452637250445 0.35353892318605484 VSNSPEPQKAVEQEDELS(ph)DVSQGGSK ddPTM_PC-9_Lapatinib_30min_R1 1 VSNSPEPQKAVEQEDELSDVSQGGSK 26 1 O60271;O60271-3;D6RHI8 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 VS(0.003)NS(0.017)PEPQKAVEQEDELS(0.968)DVS(0.012)QGGS(0.001)K 56.562 0.0020168 8943200.0 46566.0 17296.0 29810.0 22732.0 21337.0 19150.0 19797.0 18928.0 25822.0 15665.0 True False 45901.960300841434 17255.952174663067 27359.13686992767 24403.787111729 20081.999610156017 18330.999140830347 20821.991792535046 19807.463980061235 22913.654442285355 18372.674377699546 2.4983820731377295 0.9392183097528829 1.4891210886062265 1.3282653689954862 1.093036277534599 0.9977316728086258 1.133313058539177 1.078093671768505 1.2471594483869792 1.0 14.165274023996409 -4.7557342976413715 24.996207362424066 1.1574180278316448 2.498384224869884 0.8653840384566187 0.16005605675877896 64.45311434931658 282365.55937933933 0.040770618452883677 0.35166059840778563 1.7549538582569165e-05 4.7557342976413715 1.3409661970382394 VSPAS(ph)PAGSPSADFAVHGESLGDR ddPTM_PC-9_AZD4547_30min_R2 2 VSPASPAGSPSADFAVHGESLGDR 24 0 A0A0A0MRP9;Q96C92-4;Q96C92-3;Q96C92-2;Q96C92 A0A0A0MRP9 SDCCAG3 Serologically defined colon cancer antigen 3 1 VS(0.024)PAS(0.976)PAGSPSADFAVHGESLGDR;VS(0.066)PAS(0.933)PAGS(0.001)PSADFAVHGESLGDR 113.02 8.3201e-08 17826000.0 23653.0 20718.1 38458.0 53718.0 40348.0 42478.0 29875.0 51886.0 30647.0 47179.0 True False 31174.161987036863 27414.82066047261 37948.02179198918 41334.14503482676 34746.376657176035 39821.84394495128 32533.817124456295 43868.21092166613 32266.937852909457 45527.27757017 0.6847359132992071 0.602162530325229 0.8335227542103937 0.9078984565048838 0.7631990866052194 0.8746809840227084 0.7146005397382431 0.9635588434659463 0.7087385755314991 1.0 15.47444357153462 -5.270402100290203 24.067137881681628 0.8400905716362604 0.6434492206039566 0.42303895140288383 0.09432685813431624 301.772661745969 810337.7551970936 0.022468525968241344 0.04794532862770786 5.365348047792653e-06 5.270402100290203 -0.19664135103230385 VSPAS(ph)PAGSPSADFAVHGESLGDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSPASPAGSPSADFAVHGESLGDR 24 0 A0A0A0MRP9;Q96C92-4;Q96C92-3;Q96C92-2;Q96C92 A0A0A0MRP9 SDCCAG3 Serologically defined colon cancer antigen 3 1 VS(0.014)PAS(0.985)PAGS(0.002)PSADFAVHGESLGDR;VS(0.045)PAS(0.923)PAGS(0.033)PSADFAVHGESLGDR 144.23 3.0195000000000003e-07 10018400.0 18182.2 18001.3 23365.0 27781.0 32949.0 33374.0 28943.0 26751.0 29019.0 22650.0 True False 21260.08734518067 19788.350097552837 23922.110212255953 26224.52063721723 26492.879976375567 31623.808688430785 26201.309510826122 26048.814595027412 29443.347976445653 26756.265702698656 0.794583503595435 0.7395781727327132 0.8940750730339455 0.9801263348409717 0.9901561103761753 1.1819216119251343 0.9792588323782209 0.9735594228457713 1.100428150310825 1.0 14.707589156659758 -5.625405843575549 1.6532474421336907 1.0394307348477607 0.759369691016497 0.7449979941109812 0.06238451627035877 0.19239626837060364 1.0408714171921398 0.019609626902958373 0.05040662794314935 2.3691587172509345e-06 5.625405843575549 -0.28006104383126373 VSPAS(ph)PAGSPSADFAVHGESLGDR ddPTM_PC-9_Lapatinib_30min_R1 1 VSPASPAGSPSADFAVHGESLGDR 24 0 A0A0A0MRP9;Q96C92-4;Q96C92-3;Q96C92-2;Q96C92 A0A0A0MRP9 SDCCAG3 Serologically defined colon cancer antigen 3 1 VS(0.04)PAS(0.897)PAGS(0.062)PSADFAVHGESLGDR 137.11 1.1679999999999999e-06 6300000.0 16140.0 10735.0 16243.0 12198.0 17824.0 13108.0 14007.0 15611.0 18648.0 10960.0 True False 15909.8406402865 10710.143767056428 14907.563239793195 13095.081611335136 16775.627363332278 12547.401396240428 14732.21392322263 16336.344050757376 16547.66586785444 12854.421396717978 1.2376940314364238 0.8331875419760992 1.1597226183668936 1.0187219795578355 1.3050472553836978 0.9761156110413542 1.1460814507749133 1.2708735419960957 1.2873131630863939 1.0 13.649977052585882 -6.209838356378565 24.999433145503705 1.167468564320259 1.0529205845400262 0.10720094159694749 0.14286440967708325 738.1530538905099 357616.54048939166 0.04097853423155768 0.05290301190029384 6.168245401212582e-07 6.209838356378565 -0.11454797978023268 VSPASPAGS(ph)PSADFAVHGESLGDR ddPTM_PC-9_Lapatinib_30min_R1 1 VSPASPAGSPSADFAVHGESLGDR 24 0 A0A0A0MRP9;Q96C92-4;Q96C92-3;Q96C92-2;Q96C92 A0A0A0MRP9 SDCCAG3 Serologically defined colon cancer antigen 3 1 VS(0.049)PAS(0.256)PAGS(0.695)PS(0.001)ADFAVHGESLGDR 110.7 3.2067e-07 9433400.0 18075.0 13450.0 19032.0 11599.0 16917.0 16291.0 13340.0 25831.0 26259.0 16393.0 True False 17817.247185450957 13418.857351365534 17467.262425644545 12452.029153129717 15921.975320101672 15594.271906175829 14030.679926878693 27031.20256070169 23301.434900471355 19226.50820770053 0.9267021860118551 0.6979352260121295 0.9084989451516017 0.6476490176277809 0.8281262072186701 0.8110818531224545 0.7297570508023488 1.4059340504624367 1.2119431489457222 1.0 14.230809153207305 -7.7522720984667295 24.99999828410296 1.2317039642163938 0.7900977511994353 0.7018107970258531 0.12305536143644072 87.75523954114335 239318.1271590166 0.0546149355553153 0.030963333201607792 1.769000279522467e-08 7.7522720984667295 -0.44160621301695857 VSPGLPS(ph)PNLENGAPAVGPVQPR ddPTM_PC-9_AZD4547_30min_R2 2 VSPGLPSPNLENGAPAVGPVQPR 23 0 C9JRJ5;Q9UGP4 C9JRJ5 LIMD1 LIM domain-containing protein 1 1 VSPGLPS(1)PNLENGAPAVGPVQPR;VSPGLPS(1)PNLENGAPAVGPVQPR 143.72 4.6371e-06 17761100.0 45392.0 43119.0 50390.0 93430.0 86915.0 80181.0 70119.0 107445.0 71507.0 75762.0 True False 59825.711787746906 57056.37351199765 49721.79567575888 71891.15697911057 74848.3525121059 75167.26939474882 76359.4551614978 90841.84409047569 75286.71403556611 73109.59544015795 0.8183017759510892 0.7804225036192374 0.6800994503718384 0.9833340828421804 1.0237828846060457 1.0281450600595257 1.0444518903677964 1.2425433835813253 1.0297788352171937 1.0 16.15777314804513 -5.914911035320476 4.182402707128217 1.0667623195356841 0.7628367945131791 0.7771635364485443 0.07209696651097974 0.10142050508176383 3.341348739414681 0.021990256946202897 0.033477074510159716 1.216435160341288e-06 5.914911035320476 -0.303925525022505 VSPGLPS(ph)PNLENGAPAVGPVQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSPGLPSPNLENGAPAVGPVQPR 23 0 C9JRJ5;Q9UGP4 C9JRJ5 LIMD1 LIM domain-containing protein 1 1 VS(0.022)PGLPS(0.978)PNLENGAPAVGPVQPR;VSPGLPS(1)PNLENGAPAVGPVQPR 162.82 3.417e-08 4482800.0 12918.2 16773.9 16103.1 20381.6 36273.8 28506.2 31781.1 31732.9 33641.2 32137.6 True False 15104.996113919817 18439.10193715686 16487.058975346838 19239.68503003875 29166.20928365207 27011.28468970294 28770.564132761494 30899.944998786792 34133.13890710239 37963.892478898364 0.39787796054674035 0.4857010367787219 0.43428262748639146 0.5067890506942307 0.7682618240440875 0.711499346509759 0.7578402069480404 0.8139298417822156 0.8990948155823263 1.0 15.212340300572954 -6.448244809839633 0.3520999935179559 1.0002481392588785 0.26843445460555404 0.9302314981096342 0.05221934968077516 0.5558443483086127 0.12522919313295375 0.06312524745653593 0.15664500702323497 3.562502601518663e-07 6.448244809839633 -0.7318136846533244 down VSPGLPS(ph)PNLENGAPAVGPVQPR ddPTM_PC-9_Lapatinib_30min_R1 4 VSPGLPSPNLENGAPAVGPVQPR 23 0 C9JRJ5;Q9UGP4 C9JRJ5 LIMD1 LIM domain-containing protein 1 1 VS(0.016)PGLPS(0.984)PNLENGAPAVGPVQPR;VS(0.362)PGLPS(0.638)PNLENGAPAVGPVQPR;VS(0.001)PGLPS(0.999)PNLENGAPAVGPVQPR;VSPGLPS(1)PNLENGAPAVGPVQPR 181.6 2.6039999999999992e-42 9041800.0 42166.7 38810.5 37706.0 36550.6 56197.3 55592.8 51417.1 51513.4 62225.3 54083.5 True False 41565.39512557427 38720.636671759996 34605.95822936913 39238.65305322729 52891.88530214279 53215.22553714638 54079.22585219752 53906.900622912406 55216.831452542 63431.76091326614 0.6552773331077629 0.610429792808447 0.5455619981398251 0.6185963070910255 0.8338391452582388 0.8389365953423648 0.8525575370064711 0.8498408344145196 0.8704918586139067 1.0 15.952917772572725 -6.286533213740657 3.5227372328996744 0.8682516399398278 0.5997057417003445 0.8731232162085572 0.049979011402545494 0.07971793074721988 2.1101930691227184 0.01549690679987565 0.01876673348392458 5.169717197706346e-07 6.286533213740657 -0.26854589823948327 VSPKS(ph)PPTDQK ddPTM_PC-9_AZD4547_30min_R2 3 VSPKSPPTDQK 11 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 VS(0.006)PKS(0.992)PPT(0.001)DQK;VS(0.028)PKS(0.943)PPT(0.028)DQK;VS(0.002)PKS(0.99)PPT(0.008)DQK 89.44 0.017746 54285200.0 66544.4 65040.5 76246.7 120687.9 109388.1 79658.6 75093.6 89455.2 76252.8 99726.8 True False 87704.1349904949 86063.5696887008 75235.61893929131 92865.16926446752 94201.4504910486 74677.53514933128 81776.7849244209 75631.9543159973 80283.36733482356 96235.3950864755 0.9113500797880597 0.8943026587189207 0.7817873961205838 0.9649793527736904 0.9788649010730487 0.7759882430183541 0.8497578759970557 0.785905791190816 0.8342394943428276 1.0 16.554279990009718 -6.770623601727031 24.999977761078412 0.8358336344700652 0.9019401481708922 0.11041622408562601 0.07595803030295621 388.72983042582314 1058138.093868281 0.026354409128323947 0.023561565086764154 1.6958069010047119e-07 6.770623601727031 0.06610651370082699 VSPKS(ph)PPTDQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSPKSPPTDQK 11 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 VS(0.282)PKS(0.715)PPT(0.003)DQK 53.376999999999995 0.044625 19390000.0 54932.0 35633.0 41944.0 60064.0 63801.0 69209.0 65542.0 78964.0 58226.0 54597.0 True False 64230.902643544985 39170.40874970698 42944.10403350583 56698.80881011536 51299.652049310695 65579.55820451872 59333.38727701225 76891.2786692737 59077.44509723031 64495.00391038582 0.9959050895289843 0.6073402027253657 0.6658516385730525 0.8791193948743212 0.7954050537091255 1.016816097811853 0.9199687367947832 1.1922051943141547 0.9160003335966446 1.0 15.976899786397286 -6.6848220612873765 1.4301765207312647 1.0295995801885383 0.7563579781704957 0.4248632734283153 0.1247803898117999 0.35628718034190243 1.5191023244315816 0.053915678895150046 0.05210164008134041 2.0662265547397023e-07 6.6848220612873765 -0.2732416020180426 VSPPAPGS(ph)APETPEDK ddPTM_PC-9_AZD4547_30min_R2 3 VSPPAPGSAPETPEDK 16 0 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 VS(0.299)PPAPGS(0.7)APETPEDK;VS(0.002)PPAPGS(0.997)APET(0.002)PEDK;VS(0.022)PPAPGS(0.905)APET(0.073)PEDK 191.93 4.6188e-39 12190100.0 71044.0 86756.0 88131.0 100556.0 87181.0 80311.0 87617.0 73676.0 72822.0 79841.0 True False 93634.51419300094 114798.18039395325 86962.32535622765 77374.36777471314 75077.42300360023 75289.14047419785 95414.74326338027 62291.06710605319 76671.22225094053 77045.7908917092 1.2153099229600721 1.4899993765435737 1.12870961995129 1.0042646960878858 0.9744519737505766 0.9771999171248642 1.238416040111644 0.8084940966289211 0.9951383633494639 1.0 16.233428522200896 -5.482276850147101 4.16498126120987 1.0020992082372495 1.351137137989166 0.5932021713863495 0.11560598310242776 0.1377570094275147 5.159836064124688 0.030567343155504138 0.0639741994352548 3.293996624948773e-06 5.482276850147101 0.3490379297519164 VSPPAPGS(ph)APETPEDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VSPPAPGSAPETPEDK 16 0 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 VSPPAPGS(0.999)APET(0.001)PEDK;VSPPAPGS(0.999)APET(0.001)PEDK;VSPPAPGS(1)APETPEDK;VSPPAPGS(0.984)APET(0.016)PEDK 157.83 3.5456999999999996e-05 29701000.0 157918.0 201872.0 163517.0 202903.0 189106.0 133385.0 159320.0 131701.0 122872.0 126068.0 True False 184650.39837732754 221912.5180344304 167415.8654216754 191535.00273040152 152052.03680877958 126390.0557891273 144228.0562230872 128243.98829874412 124668.77054901366 148923.1304462611 1.2399040889350539 1.4901145132354543 1.124176378242918 1.2861333370877328 1.0210102107922554 0.8486932514135885 0.9684731699561734 0.8611421739151593 0.8371350385627327 1.0 17.184208322302325 -6.324729370352616 1.765122341629831 0.8934697557805752 1.3104649906958121 0.7691956679211794 0.09838553399532825 0.1590322991817663 0.9795896914616852 0.0342947512893995 0.043381263102342305 4.7344619400820225e-07 6.324729370352616 0.41699523491523693 VSPPAPGS(ph)APETPEDK ddPTM_PC-9_Lapatinib_30min_R1 4 VSPPAPGSAPETPEDK 16 0 M0R300;M0R0P8;Q13459-2;Q13459 M0R300 MYO9B Unconventional myosin-IXb 1 VSPPAPGS(0.999)APET(0.001)PEDK;VSPPAPGS(0.999)APET(0.001)PEDK;VSPPAPGS(1)APETPEDK;VSPPAPGS(1)APETPEDK 203.53 7.7459e-17 34450800.0 125228.0 169536.0 122289.0 113421.0 103343.0 96694.0 81650.0 91216.0 106014.0 70766.0 True False 123442.22575599758 169143.44980826115 112234.87046919123 121762.35870136425 97264.56792015533 92558.62302472323 85877.43748348176 95454.22836037946 94073.58694308891 82997.80881023209 1.487294996404525 2.0379266902695496 1.3522630546284344 1.467055099969738 1.1718932019343191 1.11519357380086 1.0346952373144418 1.1500813061056587 1.13344663300908 1.0 16.34078562853503 -5.880923225563475 1.1603873568788128 1.0879020744023287 1.7553062177449115 0.7091968137397645 0.15916622945383008 0.25689069228329864 0.6931824501830028 0.05603608789487101 0.12866607508240166 1.3154573577603732e-06 5.880923225563475 0.6674041433425828 VSPS(ph)KSPSLSPSPPS(ph)PLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSPSKSPSLSPSPPSPLEK 19 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 VS(0.062)PS(0.815)KS(0.111)PS(0.005)LS(0.006)PS(0.002)PPS(0.998)PLEK 72.566 0.017738999999999998 6702400.0 27469.0 22971.0 26093.0 43534.0 36623.0 31543.0 35757.0 41934.0 31279.0 30911.0 True False 32118.959162519823 25251.409069949736 26715.15607825356 41094.93111913229 29446.986050405238 29888.829551722043 32369.838101738198 40833.276932745655 31736.396200945732 36514.919608658616 0.8796119368945181 0.6915367564978011 0.7316230287391545 1.1254284977088553 0.8064371047779223 0.8185374600861682 0.8864825240930418 1.1182628188797394 0.8691350423627997 1.0 15.156198433884427 -5.951144890842893 0.32935931826490134 1.0047138580414432 0.7052510295415291 0.19489765442860008 0.1258341356046492 5.307750957118716 0.826284238561051 0.14855385451664552 0.5997671197317904 1.1190644749804678e-06 5.951144890842893 -0.2994628284999141 VSPS(ph)KSPSLSPSPPSPLEK ddPTM_PC-9_Lapatinib_30min_R1 2 VSPSKSPSLSPSPPSPLEK 19 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 VS(0.03)PS(0.56)KS(0.396)PS(0.013)LS(0.002)PSPPSPLEK;VS(0.059)PS(0.69)KS(0.247)PS(0.003)LS(0.001)PSPPSPLEK 79.935 0.0012423 13688700.0 148818.0 111749.0 125261.0 111057.0 110272.0 95989.0 75917.0 80365.0 96977.0 71859.0 True False 146695.82803012116 111490.25205633832 114962.52410144306 119224.50225529133 103786.0177630934 91883.77423128787 79847.61079526611 84099.05128685659 86054.42904691765 84279.73240390135 1.7405825083437325 1.3228595876649625 1.3640589596380992 1.4146283911287356 1.2314469303925923 1.0902238487296683 0.9474117740740469 0.9978561735794453 1.0210572173451058 1.0 16.362898113019128 -5.790376734280628 0.48056123332368517 0.946121384943947 1.7337131433110409 0.8407371779339607 0.09513914026465667 0.7851529103173365 0.2749404695832739 0.07837829591017692 0.3191611841456172 1.6204038475532337e-06 5.790376734280628 0.7875917583670938 VSPSKS(ph)PSLSPSPPS(ph)PLEK ddPTM_PC-9_AZD4547_30min_R2 2 VSPSKSPSLSPSPPSPLEK 19 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 VS(0.017)PS(0.138)KS(0.841)PS(0.004)LSPS(0.001)PPS(0.999)PLEK;VS(0.097)PS(0.148)KS(0.748)PS(0.006)LS(0.001)PS(0.013)PPS(0.987)PLEK 109.42 0.00053089 50170000.0 74301.0 82071.0 79187.0 105903.0 99720.0 98455.0 79008.0 91945.0 94686.0 98275.0 True False 97927.17244319225 108598.84576412167 78136.92864013342 81488.69953503972 85875.59929249522 92298.5932859406 86039.55894122303 77737.01293590918 99690.90865469984 94834.42216258208 1.0326121065546012 1.1451416404261119 0.8239300336135034 0.8592734333883245 0.9055319506800174 0.9732604594532763 0.9072608550692561 0.8197130447279842 1.0512101659014899 1.0 16.533123190460586 -5.255547609031297 24.99273820431675 0.9101992699600568 1.0888768805855564 0.4516803512320432 0.07517341102908005 386.74284982370193 1640540.8547352839 0.018620508065354695 0.046495022571753065 5.552037502131151e-06 5.255547609031297 0.17867761062549958 VSPSKS(ph)PSLSPSPPS(ph)PLEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VSPSKSPSLSPSPPSPLEK 19 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 VS(0.064)PS(0.372)KS(0.563)PSLS(0.001)PS(0.004)PPS(0.995)PLEK;VS(0.006)PS(0.032)KS(0.799)PS(0.128)LS(0.035)PS(0.002)PPS(0.998)PLEK;VS(0.081)PS(0.371)KS(0.537)PS(0.014)LS(0.057)PS(0.075)PPS(0.865)PLEK 107.58 0.00064321 6766600.0 76409.0 75594.0 73962.0 107588.0 98070.0 88737.0 107389.0 100760.0 97996.0 84449.0 True False 89343.53455345932 83098.47273665835 75725.53458244706 101560.19316500217 78853.88750138534 84083.4755074394 97216.33649096877 98115.15676404463 99429.00610978225 99758.93520208368 0.8955943081436698 0.8329927797276916 0.7590852331076742 1.0180561065459415 0.7904443581083683 0.8428666097639256 0.974512571671256 0.9835224941534388 0.996692736428741 1.0 16.606158445891133 -7.301847573442506 5.466491473153416 0.988888103058067 0.8552515697970946 0.4966462803532745 0.06524411173126846 0.17794000269095928 14.039761515887426 0.02736692592361866 0.01858701935906094 4.990596142331686e-08 7.301847573442506 -0.13363653326097236 VSPSKS(ph)PSLSPSPPS(ph)PLEK ddPTM_PC-9_Lapatinib_30min_R1 2 VSPSKSPSLSPSPPSPLEK 19 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 VS(0.061)PS(0.367)KS(0.503)PS(0.061)LS(0.008)PS(0.001)PPS(1)PLEK;VS(0.006)PS(0.165)KS(0.828)PSLSPSPPS(1)PLEK 124.1 8.4991e-05 24815000.0 83428.0 63768.0 76215.0 73745.0 72974.0 82134.0 71126.0 77299.0 69504.0 60704.0 True False 82238.30142117858 63620.34911389423 69948.89689840801 79168.45330610858 68681.81279240406 78621.32028370535 74808.55625780913 80890.59373387317 61675.72761043301 71196.60551700443 1.1550873924956573 0.893586831168507 0.982475167045732 1.1119694925230694 0.9646781934849444 1.1042846735850016 1.0507320639035527 1.1361580112770047 0.8662734292255342 1.0 16.11952083814947 -4.690128030217528 22.862052676231983 1.0212741320277592 1.1551073563853724 0.19100461094644705 0.08641341910150807 43303.9392561903 13875925.203599362 0.020875357189883842 153.09760066567574 2.041136128075412e-05 4.690128030217528 0.13383322435761325 VSPSKSPSLSPSPPS(ph)PLEK ddPTM_PC-9_Lapatinib_30min_R1 1 VSPSKSPSLSPSPPSPLEK 19 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 VSPSKSPSLSPS(0.005)PPS(0.995)PLEK 115.96 3.3311e-05 6831200.0 240840.0 6544.3 11172.0 6047.9 7088.0 6131.7 5082.3 5448.0 9083.8 6785.8 True False 237405.57743535272 6529.147075430593 10253.48128516713 6492.682741202964 6671.097775544163 5869.461484690826 5345.436626115111 5701.133968901819 8060.6867873453475 7958.716488489857 29.829631169635967 0.8203768892726923 1.2883335271454932 0.8157952039870856 0.838212767748683 0.7374884496990719 0.6716455641868695 0.7163383665126124 1.012812404990549 1.0 12.958320069074635 -4.761382400320603 24.999999999864418 0.8678362804732094 29.82966278775007 0.9996030413432477 0.17308305221463213 0.024255729094863555 10551.433436709533 0.04542188723294902 0.25383111171397 1.7322780391572108e-05 4.761382400320603 28.96182650727686 VSPSTSYT(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 2 VSPSTSYTPSR 11 0 Q9BTE3;Q9BTE3-2 Q9BTE3 MCMBP Mini-chromosome maintenance complex-binding protein 1 VSPS(0.001)T(0.001)S(0.001)YT(0.675)PS(0.321)R;VSPS(0.001)T(0.007)S(0.007)YT(0.949)PS(0.035)R 87.641 0.025092 49894000.0 56466.0 50587.0 93197.0 115706.0 98042.0 93670.0 65979.0 101446.0 75539.0 104910.0 True False 74421.01343423763 66938.2584672981 91961.14688616195 89031.76933987977 84430.56062810689 87812.80009236757 71851.00318174083 85769.85169716945 79531.8373240751 101237.13283211883 0.7351157757267752 0.6612026298522458 0.9083736798301152 0.879437878663759 0.8339880660994003 0.8673971460450901 0.7097297322800625 0.847217313427883 0.78559946433847 1.0 16.627379028568 -12.309368300406728 1.8462753915900703 6.504515310436007 0.8056332375520445 0.3760785714712487 0.07601480281663983 2511907.3046214576 53671.60038642902 58280494.763952285 0.021011187060290506 4.90491741626619e-13 12.309368300406728 -5.698882072883963 VSPSTSYT(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSPSTSYTPSR 11 0 Q9BTE3;Q9BTE3-2 Q9BTE3 MCMBP Mini-chromosome maintenance complex-binding protein 1 VSPSTSYT(0.964)PS(0.036)R;VSPS(0.003)T(0.015)S(0.015)YT(0.964)PS(0.003)R 107.09 0.0057523 46634000.0 42981.0 42374.0 57194.0 53198.0 61569.0 59340.0 55713.0 63037.0 51380.0 32326.0 True False 50256.83438655442 46580.61067999 58557.7218694529 50217.48853024306 49504.996426764614 56228.10593790024 50435.46131280983 61382.34554322241 52131.33529858982 38186.4479075248 1.3160908421820272 1.2198204659619858 1.5334686800736408 1.31506048040534 1.296402235333584 1.4724623267936963 1.3207685992409706 1.6074379500253742 1.3651789615215066 1.0 15.220773106670517 -8.579236084695573 21.809387898221377 0.9999999982744812 1.3867229388441744 0.5081486143504803 0.1131765489231459 10807.613229498267 4182364.178450092 0.10898023228518068 0.028138574848794118 2.634898652092846e-09 8.579236084695573 0.38672294056969325 VSPSTSYT(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 2 VSPSTSYTPSR 11 0 Q9BTE3;Q9BTE3-2 Q9BTE3 MCMBP Mini-chromosome maintenance complex-binding protein 1 VSPSTSYT(0.834)PS(0.166)R;VSPSTSYT(0.986)PS(0.014)R 101.56 0.0090098 33490000.0 113156.0 88200.0 98356.0 83809.0 90335.0 85682.0 64162.0 68859.0 106622.0 64408.0 True False 111542.37468973086 87995.77831899204 90269.54934513924 89972.5934386281 85021.67290544332 82017.58059449744 67483.99441292284 72058.44052213842 94613.1075805649 75540.83698173462 1.476583780991217 1.164876930609982 1.1949768224962338 1.1910457579439184 1.125506101103978 1.0857383088610584 0.8933445419626488 0.9539004782216243 1.2524762944239267 1.0 16.204969148272045 -1.52287874548107 0.43199839952224245 1.0287151315208072 9.10632601606965 0.5898424802171673 0.1012686236685239 60.44366959711752 0.7566301047654953 0.0687877160833102 425.5342606139893 0.0299999999861339 1.52287874548107 8.077610884548843 VSPT(ph)ASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSPTASR 7 0 P21580;A0A087WU80 P21580 TNFAIP3 Tumor necrosis factor alpha-induced protein 3;A20p50;A20p37 1 VS(0.182)PT(0.818)ASR 95.35799999999999 0.010206999999999999 0.0 18544.0 28017.0 18862.0 18870.0 35260.0 23141.0 25918.0 21340.0 25627.0 17480.0 True False 21683.13293930494 30798.342602097524 19311.741614533337 17812.77507736543 28351.056116027863 21927.445222597737 23462.859409929555 20779.84761159899 26001.746393479203 20648.985628396138 1.050082233070406 1.491518428863845 0.9352392394508792 0.8626464949866399 1.3729999442219558 1.0619139175748895 1.1362717681232644 1.0063374533528122 1.2592263301167703 1.0 14.333783291226759 -8.909897646948233 0.01402813810292415 2.453638610436332e-05 2.16997485384632 0.026109770937564947 0.18661189040320514 4941.14302808187 32.00475110626464 2549.847399812338 2395.3642157982467 1.230558750556558e-09 8.909897646948233 2.169950317460216 VSPT(ph)ASR ddPTM_PC-9_Lapatinib_30min_R1 1 VSPTASR 7 0 P21580;A0A087WU80 P21580 TNFAIP3 Tumor necrosis factor alpha-induced protein 3;A20p50;A20p37 1 VS(0.351)PT(0.632)AS(0.017)R 98.58200000000001 0.0082542 0.0 15502.0 27954.0 24554.0 23867.0 32403.0 22669.0 25984.0 25087.0 18426.0 16005.0 True False 15280.938637281364 27889.27423048864 22535.264901180966 25622.258797978004 30497.119246749106 21699.499714019992 27329.324379311558 26252.633604596143 16350.669845618073 18771.442924678027 0.8140524251970079 1.4857288458003293 1.2005078667423483 1.3649594706592052 1.6246550341985604 1.1559846411962593 1.455898967861594 1.3985410556842655 0.8710395845021873 1.0 14.196251931170936 -8.262130406898638 24.996767562767985 0.9355197525976203 1.326290662806719 0.3325261237690532 0.2129517389875033 66.12881163166142 2391841.240809138 0.16192821565183804 0.05132231959748494 5.468517334383009e-09 8.262130406898638 0.3907709102090987 VSQGSAESLS(ph)PSFR ddPTM_PC-9_AZD4547_30min_R2 1 VSQGSAESLSPSFR 14 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 VSQGSAES(0.223)LS(0.749)PS(0.027)FR 174.4 0.00013068 32657000.0 32131.0 27319.0 36973.0 55750.0 50109.0 46417.0 38608.0 40997.0 44058.0 37120.0 True False 42347.989633682046 36149.332497837706 36482.71386227095 42897.69882891382 43152.23029430041 43514.537652262436 42044.037206393594 34661.8556673389 46386.81593381032 35820.440098448664 1.1822297413793104 1.0091816962182798 1.0184887109706664 1.1975759848570833 1.2046817452745164 1.214796287613088 1.1737442949009012 0.9676557734096646 1.2949817424442889 1.0 15.1284954422767 -4.451458241089596 22.42122133963468 1.1238727259141834 3.51264339792066 0.028027174844197478 0.10770461566995748 2115.92604235361 724199.568732405 0.025906385234404052 22971.368606099273 3.536240216334984e-05 4.451458241089596 2.3887706720064767 VSQGSAESLS(ph)PSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSQGSAESLSPSFR 14 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 VSQGS(0.003)AES(0.34)LS(0.613)PS(0.043)FR;VSQGSAES(0.012)LS(0.976)PS(0.012)FR 171.87 0.00020529 35021000.0 62779.0 61451.0 76078.0 91329.0 108887.0 107203.0 102922.0 104333.0 101100.0 96056.0 True False 73406.24475823046 67551.44916448915 77891.98804742187 86212.13222261291 87551.37400186955 101581.08595990436 93172.48306924803 101594.36929995126 102578.39623759093 113470.19242112232 0.646920950709219 0.5953232978911785 0.6864533000732127 0.7597777917098574 0.7715803783687951 0.8952226465158896 0.8211185782029581 0.8953397110926165 0.904011829440558 1.0 16.79195383896611 -5.5055747767503815 0.2709730531878282 1.000945625891535 0.3850071000052106 0.9186554171416437 0.034931700365621716 1.520319363746027 0.1289486856725664 0.04823536261201224 0.3050947466728111 3.121944824012842e-06 5.5055747767503815 -0.6159385258863244 VSQGSAESLS(ph)PSFR ddPTM_PC-9_Lapatinib_30min_R1 2 VSQGSAESLSPSFR 14 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 VSQGSAES(0.068)LS(0.9)PS(0.032)FR;VSQGSAES(0.132)LS(0.434)PS(0.434)FR 155.63 0.00024028 49845000.0 72825.0 77511.0 94563.0 74959.0 98979.0 101432.0 89543.0 90486.0 110509.0 85942.0 True False 71786.50214553079 77331.52804176176 86788.39516373604 80471.73491589374 93157.24982020108 97093.98980954051 94179.09840273618 94690.30989538341 98062.31270864049 100796.96018948306 0.7121891573970387 0.7672009939227351 0.8610219494773154 0.7983547793963135 0.9242069368469001 0.9632630748687111 0.9343446292992736 0.9394163248314229 0.9728697425428123 1.0 16.621092605480136 -3.6399034405588058 0.2997371033698526 0.9968381686153004 0.19209494512022685 0.9021208738815545 0.02897507235296227 4.582065821526422 0.19630376012432388 0.032376774376969536 1.5294957442089108 0.00022913770525008693 3.6399034405588058 -0.8047432234950735 VSQGSAESLSPS(ph)FR ddPTM_PC-9_AZD4547_30min_R2 1 VSQGSAESLSPSFR 14 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 VSQGSAES(0.022)LS(0.223)PS(0.755)FR 97.073 0.0027921 33230000.0 36867.0 28283.0 47462.0 58181.0 38207.0 41080.0 37017.0 44202.0 33495.0 35051.0 True False 48589.93911876248 37424.92664579025 46832.6228688801 44768.26933748944 32902.61755082593 38511.261105951264 40311.44128856902 37371.59656091212 35265.477318602236 33823.87515869407 1.4365574284670024 1.1064647817614288 1.384602522601325 1.3235700855518981 0.9727630969678724 1.1385821679291632 1.191804342330284 1.1048880823256628 1.0426208455756323 1.0 15.04575433651675 -1.5228787885915178 0.1639081877564042 0.9697626227040969 2.5031447362684633 0.476069963569533 0.11083282694172587 60.07720170292147 0.6333438083075071 0.32156684332506397 22.369675148752517 0.02999999700816981 1.5228787885915178 1.5333821135643664 VSQPIEGHAASFAQFK ddPTM_PC-9_Lapatinib_30min_R1 2 VSQPIEGHAASFAQFK 16 0 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 ; 147.64 2.5316e-05 3326500.0 45594.0 56731.0 57975.0 66443.0 65076.0 56780.0 59853.0 50044.0 63847.0 56182.0 False True 44943.82119908442 56599.642855042235 53208.519289971715 71329.43986735042 61248.35762433858 54351.65176064475 62951.89547702179 52369.22693460394 56655.87852128386 65892.98384219068 0.6820729397642986 0.8589631179943926 0.8074990110844363 1.0825043230426428 0.9295125831761442 0.824847329585398 0.9553656824494001 0.7947618074182945 0.8598165573586853 1.0 16.007837237575593 -4.544986078292672 1.5041795810964291 0.9060886777800985 0.478926652607586 0.38817176923693164 0.08537254917057337 2.2952793110575462 3.1140628536771833 0.024516492829960154 1.7303992765697342 2.8511096609701747e-05 4.544986078292672 -0.4271620251725125 VSQSALNPHQS(ph)PDFKR ddPTM_PC-9_AZD4547_30min_R2 3 VSQSALNPHQSPDFKR 16 1 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 VS(0.001)QS(0.015)ALNPHQS(0.983)PDFKR;VSQSALNPHQS(1)PDFKR;VSQSALNPHQS(1)PDFKR 80.016 0.0038626999999999997 67437000.0 69612.0 68823.0 107795.0 162215.0 137771.0 113760.0 119921.0 138827.0 95971.0 139703.0 True False 91747.16798045114 91068.6888428816 106365.5678679981 124818.83794676687 118643.87475056511 106646.56921648036 130593.7366822399 117374.47707709453 101043.83113132037 134812.04049228368 0.6805561850812764 0.6755234065913731 0.7889916025274183 0.9258730710623078 0.8800688300341838 0.7910759960834846 0.9687097399116571 0.8706527743997227 0.7495163693268472 1.0 17.040589828395497 -5.4566489870720565 3.1926144862289543 0.877599289681557 0.6783301393054243 0.5721058013495831 0.0708361954010188 0.1784058393704562 3.5284151655774356 0.01903116088824103 0.04306910215037197 3.4942261771520483e-06 5.4566489870720565 -0.1992691503761327 VSQSALNPHQS(ph)PDFKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSQSALNPHQSPDFKR 16 1 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 VSQSALNPHQS(0.999)PDFKR 70.072 0.0093476 12810000.0 27364.0 31483.0 33542.0 34580.0 38867.0 30503.0 37769.0 36254.0 29947.0 26176.0 True False 31996.184736364343 34608.4241761015 34341.76848874338 32642.59470987261 31251.290359094044 28903.368982537435 34191.24689611967 35302.37091428819 30384.91822084215 30921.50159089802 1.0347552056069187 1.1192349140731495 1.1106112808846302 1.055660075689248 1.0106653542431168 0.9347336803024262 1.105743419206528 1.1416771210321726 0.9826469174377412 1.0 14.916322759780547 -1.5228787530314685 0.043862830103613235 0.8938708119047291 1.3271559670059783 0.09099511966214968 0.06187070875088908 1909.0852924527617 6.3801940759067195 16.308620493475132 59.07848309948608 0.02999999946457085 1.5228787530314685 0.4332851551012492 VSQSALNPHQS(ph)PDFKR ddPTM_PC-9_Lapatinib_30min_R1 2 VSQSALNPHQSPDFKR 16 1 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 VSQSALNPHQS(1)PDFKR;VSQSALNPHQS(1)PDFKR 76.678 0.0051643 51408000.0 75451.0 55803.0 73022.0 55007.0 68682.0 59188.0 46300.0 63482.0 66239.0 41883.0 True False 74375.05490398116 55673.79158202608 67018.41303307128 59052.398277972796 64642.25979400737 56656.66721396688 48697.1874523601 66431.60547243484 58778.46629240716 49122.42074441051 1.5140755234959398 1.1333682407815993 1.3643141363446976 1.2021475607895848 1.3159420650368256 1.1533769377685579 0.9913433970556348 1.3523683170682073 1.1965710443758084 1.0 15.584094037771845 -1.5228787452803376 0.08532838360327463 0.8879435000247597 2.1592482721921127 0.3540788425674537 0.12643106238217325 219.58185893926859 1.3613632994606806 2.8373440086165655 32.75307457605482 0.029999999999999995 1.5228787452803376 1.271304772167353 VSRPENEQLR ddPTM_PC-9_AZD4547_30min_R2 1 VSRPENEQLR 10 1 Q8ND56-3;Q8ND56-2;Q8ND56;K7EMZ9;A0A140TA76 Q8ND56-3;K7EMZ9 LSM14A Protein LSM14 homolog A 0 79.07 0.025315 2542300.0 9865.5 8922.4 14962.0 20248.0 16613.0 12820.0 9950.9 15541.0 11137.0 11741.0 False True 13002.523784852334 11806.391312958278 14763.594104002872 15580.136428481565 14306.571711253731 12018.363373376227 10836.510822552376 13139.49554665253 11725.679083363882 11329.951163682268 1.1476239921078772 1.0420513859585927 1.3030589356225133 1.375128295205994 1.2627213925787173 1.060760386320167 0.9564481493343416 1.1597133435818054 1.0349275927110881 1.0 13.467854022167256 -6.789030276221851 9.038724118739475 1.0466476322197777 1.2284381932553305 0.4755747803188932 0.09641387002728952 0.2791333746232079 83.70568406355135 0.037430559043402256 0.03342931585494779 1.6254354368819374e-07 6.789030276221851 0.1817905610355528 VSRPENEQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSRPENEQLR 10 1 Q8ND56-3;Q8ND56-2;Q8ND56;K7EMZ9;A0A140TA76 Q8ND56-3;K7EMZ9 LSM14A Protein LSM14 homolog A 0 88.056 0.013262999999999999 1049000.0 7222.8 7116.3 11390.0 8652.0 9496.4 9871.0 8854.1 8810.0 10671.0 6781.1 False True 8445.477383197354 7822.759234011728 11661.580796815548 8167.256490162461 7635.6485904777965 9353.347383097627 8015.3755498671735 8578.746834966598 10827.043187451378 8010.459750841941 1.0543062003787849 0.9765680719124161 1.4557941940336014 1.0195740000196667 0.9532097817076292 1.167641767641931 1.0006136725204462 1.0709431295831586 1.3516132062599027 1.0 12.967669331444045 -11.329352551919262 2.469625949112043 0.962885520980225 1.1116216651636297 0.046197546716470805 0.15756207684820933 34628825.401096225 23169756.10894527 7694587.252400657 0.03887018942358624 4.684329628751828e-12 11.329352551919262 0.14873614418340475 VSRPENEQLR ddPTM_PC-9_Lapatinib_30min_R1 1 VSRPENEQLR 10 1 Q8ND56-3;Q8ND56-2;Q8ND56;K7EMZ9;A0A140TA76 Q8ND56-3;K7EMZ9 LSM14A Protein LSM14 homolog A 0 111.27 0.0021003 2491900.0 16385.0 16176.0 17035.0 17494.0 17312.0 14198.0 17376.0 14104.0 18479.0 14306.0 False True 16151.346895359002 16138.545465850479 15634.448057001606 18780.56711827324 16293.742196701556 13590.784637154518 18275.644258579036 14759.323329183408 16397.70042750334 16778.77303845323 0.9626059580366034 0.961843004185378 0.9317992454615671 1.1193051527207825 0.9710925917741369 0.8099987171891205 1.0892121978582885 0.8796425874143663 0.9772884101789472 1.0 14.034349600925609 -6.524512946582663 24.999972194162694 0.9454651151807136 0.9944187601067472 0.053263206143864816 0.08302096037476858 159.07604091137406 2433486.860662381 0.026742736735203467 0.02693874782294192 2.988732549696175e-07 6.524512946582663 0.0489536449260336 VSS(ph)LAGFTDCHR ddPTM_PC-9_AZD4547_30min_R2 1 VSSLAGFTDCHR 12 0 H0YLN8;Q96QT4 H0YLN8 TRPM7 Transient receptor potential cation channel subfamily M member 7 1 VS(0.149)S(0.851)LAGFTDCHR 164.92 0.00045379 2637500.0 9891.9 12799.0 21756.0 17311.0 18316.0 11729.0 17982.0 19236.0 13364.0 12911.0 True False 13037.318435698218 16936.0264519135 21467.501224882133 13320.216402283902 15773.139557173485 10995.583775844756 19582.363164250164 16263.51819930557 14070.393756853262 12458.989819802553 1.0464185800181376 1.359341864538252 1.7230531154910556 1.0691249126082838 1.2660046910146245 0.8825421591057221 1.57174565895588 1.3053641133453715 1.129336644491796 1.0 13.60489947832531 -13.800669044041658 0.2262641084115092 6.963153277839254e-09 1.3059706623520762 0.10226111180104669 0.23718700964872164 269.9117198209672 3.630077129366587 123.16666794356487 0.4390014129107644 1.582453495321803e-14 13.800669044041658 1.3059706553889228 VSS(ph)PAPMEGGEEEEELLGPK ddPTM_PC-9_AZD4547_30min_R2 2 VSSPAPMEGGEEEEELLGPK 20 0 O14497-2;O14497;H0Y488;A0A1B0GTU5;O14497-3 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 VS(0.176)S(0.824)PAPMEGGEEEEELLGPK;VS(0.095)S(0.905)PAPMEGGEEEEELLGPK 90.475 0.00046595 6929500.0 77569.0 73964.0 79138.0 68610.0 69017.0 93963.0 86204.0 101082.0 87502.0 81624.0 True False 102234.3284645696 97871.41655514721 78088.57841214935 52793.024513933226 59435.18087013772 88087.47875604898 93875.98900072424 85462.09953328186 92127.17708112653 78766.36860441208 1.2979439102749617 1.2425533674998566 0.9913949290252697 0.6702482982181819 0.7545756129578439 1.118338706186269 1.1918283229762325 1.0850074853964349 1.1696258024007222 1.0 16.265292143690765 -5.231855496557326 5.060253360309485 0.9910869616671563 1.2777903984851082 0.3170686708492253 0.1602973962488455 0.25441716310471224 18.12354020086979 0.04795846896014168 0.1270444905236863 5.863332235782266e-06 5.231855496557326 0.28670343681795196 VSS(ph)PAPMEGGEEEEELLGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VSSPAPMEGGEEEEELLGPK 20 0 O14497-2;O14497;H0Y488;A0A1B0GTU5;O14497-3 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 VS(0.142)S(0.858)PAPMEGGEEEEELLGPK;VS(0.073)S(0.927)PAPMEGGEEEEELLGPK;VS(0.061)S(0.939)PAPMEGGEEEEELLGPK 98.70299999999999 0.00027101 9553500.0 87079.0 121489.0 100878.0 104157.0 117028.0 88392.0 118791.0 74877.0 90039.0 83884.0 True False 101819.75481135317 133549.62502717035 103283.31410194548 98321.42097155003 94097.20349252716 83756.56791477717 107538.25650763701 72911.55808873955 91355.65003794739 99091.50517462133 1.027532628875947 1.347740402084176 1.042302404428485 0.9922285547917126 0.9495990935520345 0.8452446833578663 1.0852419318702509 0.73580028843293 0.9219322067714922 1.0 16.596473764229188 -5.66985387588333 2.224056614539898 0.9185914131965486 1.1887097584989308 0.43161689254872493 0.11505710162927782 0.25388761581610614 2.541567586064077 0.03244927012301282 0.06723778486564003 2.138681556125887e-06 5.66985387588333 0.2701183453023822 VSS(ph)PAPMEGGEEEEELLGPK ddPTM_PC-9_Lapatinib_30min_R1 2 VSSPAPMEGGEEEEELLGPK 20 0 O14497-2;O14497;H0Y488;A0A1B0GTU5;O14497-3 O14497-2 ARID1A AT-rich interactive domain-containing protein 1A 1 VS(0.162)S(0.838)PAPMEGGEEEEELLGPK;VS(0.157)S(0.843)PAPMEGGEEEEELLGPK 96.12799999999999 0.00034948 2507700.0 47982.0 54967.0 46671.0 46871.0 57801.0 53737.0 48343.0 57381.0 52866.0 47528.0 True False 47297.76788117888 54839.72728866243 42833.890535269864 50318.04969707243 54401.258821138275 51438.793777065235 50845.96399588432 60047.130739639295 46911.67437634021 55743.15147292078 0.8484946873546512 0.9837930909827153 0.7684153013142422 0.9026768018581837 0.9759272194641816 0.9227823045141871 0.9121472800220949 1.0772109066852693 0.8415683924711223 1.0 15.766506947937154 -6.008575017854341 24.73411873345888 0.9536205905860287 0.8714162120634175 0.21839467545636138 0.07544075745123986 566.524931802868 1634116.3359853353 0.02070597325463129 0.029085022853055066 9.804489418528975e-07 6.008575017854341 -0.0822043785226112 VSS(ph)PIEK ddPTM_PC-9_AZD4547_30min_R2 4 VSSPIEK 7 0 Q06190 Q06190 PPP2R3A Serine/threonine-protein phosphatase 2A regulatory subunit B subunit alpha 1 VS(0.014)S(0.986)PIEK;VS(0.008)S(0.992)PIEK;VS(0.11)S(0.89)PIEK;VS(0.006)S(0.994)PIEK 106.68 0.010019 247721000.0 1345170.0 1257650.0 1520620.0 1812190.0 1613480.0 1592930.0 1441850.0 1627310.0 1469180.0 1453030.0 True False 1772906.0787258423 1664160.7678138134 1500455.585244541 1394417.5935563997 1389476.1526920912 1493323.8352848848 1570171.8567664353 1375846.6313636878 1546837.8554095828 1402159.861967913 1.264410804227124 1.186855231669651 1.0701030787878003 0.9944783268858893 0.9909541632021754 1.0650168185452293 1.1198237086623772 0.9812337870181971 1.1031822386062429 1.0 20.419219411483347 -5.152027380070449 2.327287762212395 1.037823350057027 1.2611139469583228 0.7368815345378137 0.04565311616180284 0.17116504369156632 1.6665929493318323 0.0126103773328695 0.05529986014571615 7.046486430338726e-06 5.152027380070449 0.2232905969012957 VSS(ph)PIEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 VSSPIEK 7 0 Q06190 Q06190 PPP2R3A Serine/threonine-protein phosphatase 2A regulatory subunit B subunit alpha 1 VS(0.014)S(0.986)PIEK;VS(0.014)S(0.986)PIEK;VS(0.068)S(0.932)PIEK;VS(0.024)S(0.976)PIEK;VS(0.029)S(0.971)PIEK 120.87 0.0058682 152338500.0 950340.0 1039610.0 1045750.0 1170480.0 1367030.0 1176080.0 1483130.0 1364320.0 1159230.0 913750.0 True False 1111213.7919294166 1142815.6102568656 1070684.6460289583 1104901.8003473612 1099170.284806965 1114404.2944294855 1342637.1894686609 1328508.0456165327 1176181.5457023035 1079405.641758978 1.0294682081877993 1.0587452631751637 0.9919205575803661 1.023620553387914 1.018310672358335 1.032424003837403 1.2438671223551565 1.2307773780500373 1.0896566593682255 1.0 20.04180570234068 -7.172108746808209 8.387674458644383 1.1601187884631678 1.0248224681173113 0.4041914644433152 0.06703907704477118 0.27962790656540465 23.976707886758216 0.024846841336575644 0.019232884934310353 6.72808164846863e-08 7.172108746808209 -0.1352963203458566 VSS(ph)PIEK ddPTM_PC-9_Lapatinib_30min_R1 4 VSSPIEK 7 0 Q06190 Q06190 PPP2R3A Serine/threonine-protein phosphatase 2A regulatory subunit B subunit alpha 1 VS(0.001)S(0.999)PIEK;VS(0.007)S(0.993)PIEK;VS(0.031)S(0.969)PIEK;VS(0.065)S(0.935)PIEK 129.42 0.0044245 186012000.0 745640.0 711940.0 804950.0 804820.0 934020.0 925180.0 964840.0 965980.0 1066720.0 814850.0 True False 735007.0368663719 710291.5466714626 738770.1181968554 864009.1476008157 879082.7799539738 885612.208099918 1014794.6942016227 1010862.9572833658 946574.7605404167 955695.7367806241 0.769080585566209 0.7432193315669325 0.7730181162945137 0.904062992382214 0.9198354100806914 0.9266675302782129 1.0618386743254506 1.0577246694524127 0.9904561923955708 1.0 19.866191857385907 -6.173208823502176 0.8327269827101222 1.0303805152247774 0.7336600836388557 0.896826884605292 0.03606783344733497 0.20014585888537617 0.29290796428471116 0.01942762023968009 0.036554740673595564 6.711060847884705e-07 6.173208823502176 -0.29672043158592165 VSS(ph)PLASFLQQQR ddPTM_PC-9_Lapatinib_30min_R1 1 VSSPLASFLQQQR 13 0 Q8NEV8-2;Q8NEV8;E9PPH6 Q8NEV8-2 EXPH5 Exophilin-5 1 VS(0.001)S(0.995)PLAS(0.004)FLQQQR 101.72 0.0019314 9403500.0 31448.0 32283.0 29958.0 27750.0 40351.0 36634.0 30938.0 35289.0 39465.0 36945.0 True False 30999.5457531431 32208.250696961608 27494.96888122421 29790.827571286278 37977.63351311831 35067.24921802499 32539.818259203374 36928.655768828205 35020.036115126306 43330.8940238819 0.7154144046983578 0.7433091659546645 0.6345350009642152 0.6875193379316616 0.8764562644884933 0.8092897690663298 0.7509611558272717 0.8522477230327837 0.8082001745873268 1.0 15.403108382845472 -14.522878682935966 0.07236990583931975 1.8560104770674721 0.47388971809100466 0.681076290754788 0.05648542585877088 181.3682766737182 0.9379261370306365 25.231966674537766 2.9190828422156248 3.000000430659693e-15 14.522878682935966 -1.3821207589764675 VSS(ph)PLPSPSAMTDAANSQAAAK ddPTM_PC-9_AZD4547_30min_R2 1 VSSPLPSPSAMTDAANSQAAAK 22 0 A0A0U1RRM1;Q8WXI9;A0A0U1RR30 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 VS(0.224)S(0.766)PLPS(0.007)PS(0.002)AMT(0.001)DAANSQAAAK 57.145 0.0077446 4939400.0 12402.0 13646.0 18171.0 24538.0 19159.0 18508.0 15084.0 21944.0 14702.0 17147.0 True False 16345.578022374802 18056.802637925743 17930.040667279507 18881.143208320853 16499.1035584127 17350.691834200257 16426.44677842005 18553.05902295495 15479.117705272134 16546.688749140598 0.9878458627091634 1.0912638118526026 1.0836029455265337 1.1410828773401265 0.997124186509499 1.0485899684975593 0.9927331702104571 1.1212550924376672 0.9354812881263684 1.0 14.014254919654402 -6.291069131383723 24.994070443629962 1.0224064674447828 1.0775895467227852 0.2061102999440847 0.05687076970975636 1183.8796627491636 998653.8534553027 0.016979505587994582 0.019255087245650854 5.11600392050774e-07 6.291069131383723 0.05518307927800237 VSS(ph)PLSPLSPGIK ddPTM_PC-9_AZD4547_30min_R2 1 VSSPLSPLSPGIK 13 0 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 VS(0.055)S(0.945)PLSPLSPGIK 122.52 0.00018059 7267900.0 27405.0 25664.0 31384.0 39602.0 42768.0 30703.0 27138.0 36147.0 28463.0 34272.0 True False 36119.219940588715 33959.38611312663 30967.8276540587 30472.37074480079 36830.40142941669 28783.13655637835 29553.22942672786 30561.31172542622 29967.496071633843 33072.14771158495 1.092134089856414 1.026827359664667 0.9363718354224355 0.9213907427646898 1.1136380301214988 0.8703134978529324 0.8935987370537646 0.9240800443909726 0.906124885900181 1.0 15.013329117012022 -6.788566079117914 24.999998358283527 0.9125018899510517 1.0086487731072427 0.36832618053203836 0.06413173794523291 257.9489103884635 237724.160906271 0.022996647214314374 0.020285887942690473 1.6271737177823448e-07 6.788566079117914 0.09614688315619091 VSS(ph)PLSPLSPGIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSSPLSPLSPGIK 13 0 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 VS(0.002)S(0.583)PLS(0.231)PLS(0.183)PGIK 182.23 7.188600000000001e-05 9289700.0 41885.0 45929.0 42954.0 44240.0 65489.0 74770.0 78907.0 77589.0 81405.0 71279.0 True False 48975.30323354116 50488.5275858135 43978.18626395214 41761.376228015186 52656.90056672007 70848.92957493769 71432.35772279152 75552.37096234092 82595.3941218705 84201.31845574635 0.5816453249396694 0.5996168291871669 0.5222980716990285 0.4959705737857738 0.6253690741718603 0.8414230427065549 0.8483520095986881 0.8972825170433518 0.9809275630913086 1.0 16.361555203276687 -6.832764980259435 1.7414433862429997 0.9309731057238995 0.5474658227311964 0.9339890048109663 0.047184522324006425 0.09039526626229603 0.5654045601876356 0.021901539638977476 0.018933062630973673 1.4697214065578623e-07 6.832764980259435 -0.3835072829927031 VSS(ph)PLSPLSPGIK ddPTM_PC-9_Lapatinib_30min_R1 1 VSSPLSPLSPGIK 13 0 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 VS(0.059)S(0.659)PLS(0.16)PLS(0.122)PGIK 168.82 0.00026229 9149700.0 31469.0 30166.0 29847.0 33193.0 53986.0 59431.0 61149.0 67763.0 68686.0 63085.0 True False 31020.246289292198 30096.15248039352 27393.094872751804 35634.12394860202 50810.64962055969 56889.274670427556 64314.99601564507 70911.51636099383 60949.859384354895 73989.15819452138 0.41925394268898614 0.4067643586546715 0.37023120064069276 0.48161277703576566 0.6867310138463236 0.7688866322936485 0.8692489222077316 0.9584041512482644 0.8237674393336726 1.0 16.17502626427848 -6.535214861670953 1.1166535209705855 0.9188295451351103 0.3846562971393858 0.9542470332432218 0.048883244484481524 0.09050101870774123 0.23936403383035135 0.022863594815476708 0.025853842469522936 2.9159840110770375e-07 6.535214861670953 -0.5341732479957244 down VSS(ph)PPNAMMSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSSPPNAMMSSR 12 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 VS(0.153)S(0.845)PPNAMMS(0.001)S(0.001)R 61.419 0.033414 15642000.0 27285.0 29203.0 28103.0 29109.0 34399.0 28673.0 32609.0 34955.0 28527.0 24456.0 True False 31903.811596685468 32102.080844096567 28773.08210122099 27478.1171026513 27658.762885287673 27169.33740406831 29520.039451284538 34037.468287883916 28944.153407218222 28889.67920641052 1.1043324977317892 1.1111954762368295 0.995964056770708 0.9511395715516979 0.9573925237338837 0.9404513359234368 1.021819565401548 1.178187824263937 1.0018855938281106 1.0 14.818266563725768 -10.599370571841792 14.936206943984672 1.0000116523531675 1.0277428144178784 0.01325342264588758 0.07457521041604205 0.0 0.0 0.07951109462226534 0.01928427303153414 2.5155295777815554e-11 10.599370571841792 0.027731162064710935 VSS(ph)PPNAMMSSR ddPTM_PC-9_Lapatinib_30min_R1 2 VSSPPNAMMSSR 12 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 VS(0.007)S(0.992)PPNAMMSSR;VS(0.246)S(0.744)PPNAMMS(0.009)S(0.001)R 84.169 0.0091187 15317000.0 121496.0 107372.0 117255.0 106877.0 112619.0 118398.0 87600.0 90988.0 127154.0 89506.0 True False 119763.44476036234 107123.38673091616 107614.7465173893 114737.09111122055 105994.97183747307 113334.39353921835 92135.49936990804 95215.63464802457 112832.57752901982 104976.99284075167 1.1408542149996759 1.0204463266862724 1.025126969303065 1.092973688866043 1.0096971628656353 1.0796117365558824 0.8776732584603184 0.9070143092445512 1.0748314890309816 1.0 16.67971365040855 -7.23895527232025 24.973219481825915 0.9571309465077451 1.057017025160735 0.3672804244907436 0.06159709343518366 827.7676566277614 919407.2771590449 0.023209485066793968 0.01796401522794558 5.768258672189517e-08 7.23895527232025 0.09988607865298982 VSS(ph)PSPATDGK ddPTM_PC-9_AZD4547_30min_R2 1 VSSPSPATDGK 11 0 A0A0A0MQS0;F8W9L8;A8MW92-4;A8MW92 A0A0A0MQS0 PHF20L1 PHD finger protein 20-like protein 1 1 VS(0.258)S(0.741)PS(0.001)PATDGK 93.839 0.006883 8792100.0 62252.0 58085.0 65821.0 66825.0 64283.0 66524.0 74499.0 77279.0 62414.0 54419.0 True False 82046.84107796133 76859.8403359165 64948.170533322635 51419.5286859581 55358.41505534964 62364.24376368798 81129.26667631381 65337.30624475646 65713.07661929357 52513.807373854455 1.5623860691314255 1.463612032331585 1.2367827392698056 0.9791620767447692 1.0541687572040617 1.1875780272358971 1.5449130568412452 1.2441928992047635 1.2513485482298272 1.0 15.680409177772267 -5.2126466073812585 3.3471489670050176 1.1945753052684969 1.5386523854906518 0.4271315000671939 0.15296490501671553 0.2630852888556137 5.923860571005194 0.04443843249341813 0.13589022435020806 6.128488741729818e-06 5.2126466073812585 0.3440770802221549 VSS(ph)PSPELGTTPASIFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSSPSPELGTTPASIFR 17 0 A0A5E8;Q99501 A0A5E8 GAS2L1 GAS2-like protein 1 1 VS(0.064)S(0.934)PS(0.002)PELGTTPASIFR;VS(0.253)S(0.559)PS(0.187)PELGTTPASIFR 120.32 8.7077e-05 14738200.0 36011.0 40407.9 41181.4 44622.0 53402.0 51018.0 47886.5 47827.0 46574.0 40054.7 True False 42106.9510503295 44419.32926549223 42163.3207573292 42121.97400647591 42938.26144946459 48342.52626794394 43350.34405176292 46571.59192689525 47255.05664064857 47316.300037169254 0.8899037121933128 0.9387743595885285 0.8910950502090794 0.8902212128460394 0.9074729303799007 1.0216886407003196 0.9161820348951444 0.9842610662776041 0.9987056596464099 1.0 15.530049644124766 -6.696781338051848 10.0142652407663 0.9788902212305159 0.9038677790966989 0.6574657010060829 0.028991427985572443 0.26521282894119996 39.22873307533251 0.009423301591901263 0.009414439452151565 2.0101046209080204e-07 6.696781338051848 -0.07502244213381704 VSS(ph)PSPELGTTPASIFR ddPTM_PC-9_Lapatinib_30min_R1 3 VSSPSPELGTTPASIFR 17 0 A0A5E8;Q99501 A0A5E8 GAS2L1 GAS2-like protein 1 1 VS(0.07)S(0.846)PS(0.056)PELGT(0.001)TPAS(0.027)IFR;VS(0.09)S(0.91)PS(0.001)PELGTTPASIFR;VS(0.023)S(0.973)PS(0.004)PELGTTPASIFR 205.66 2.8746e-17 24283100.0 48350.5 41485.0 49991.1 37625.9 40994.8 42532.8 37287.3 39616.5 50183.2 35865.0 True False 47661.01300360426 41388.94403133078 45881.024729226505 40393.03420232292 38583.566462877825 40713.77129279941 39217.85394583987 41457.22721714366 44531.03956347666 42064.217462891436 1.1330535994316369 0.9839466065865512 1.090737626813151 0.9602706680079615 0.9172538749096141 0.9678956069661019 0.932332902197394 0.9855699147075956 1.0586441933161226 1.0 15.360305885058139 -1.5228957289304101 0.7826287272388001 0.9752161136532814 33.67650053286055 0.4193858485171438 0.050422316135129965 449.5775844241636 1.689853323214061 0.018778181125624963 26018.8106048432 0.02999882683395479 1.5228957289304101 32.70128441920727 VSS(ph)PTKPK ddPTM_PC-9_AZD4547_30min_R2 1 VSSPTKPK 8 1 Q8WUA4;A0A087WZD8;Q8WUA4-2 Q8WUA4 GTF3C2 General transcription factor 3C polypeptide 2 1 VS(0.017)S(0.981)PT(0.001)KPK 99.815 0.024537 50729000.0 111620.0 101970.0 96168.0 125390.0 108440.0 99211.0 117690.0 100740.0 118140.0 134700.0 True False 147112.83815977068 134929.80836796775 94892.74948494497 96483.27275618834 93384.97781065152 93007.3204864298 128164.18200426002 85172.94777490335 124384.63921240969 129984.19399948906 1.1317748230246283 1.0380478134787536 0.7300329875901526 0.7422692697280379 0.718433333602227 0.7155279240089406 0.9859982053261322 0.6552561904198764 0.9569212639261249 1.0 16.987976677498793 -5.131028649411938 4.281653287033905 0.7980257963178263 1.1116988585534096 0.45333328300679776 0.12001162620095135 0.17532937633273213 5.150553016186343 0.029326125642240273 0.08842914714216095 7.3955648660203654e-06 5.131028649411938 0.3136730622355832 VSS(ph)PTKPK ddPTM_PC-9_Lapatinib_30min_R1 1 VSSPTKPK 8 1 Q8WUA4;A0A087WZD8;Q8WUA4-2 Q8WUA4 GTF3C2 General transcription factor 3C polypeptide 2 1 VS(0.012)S(0.988)PTKPK 137.95 0.014894 71574000.0 259670.0 341570.0 340900.0 298450.0 352620.0 292560.0 376970.0 392800.0 377410.0 284340.0 True False 255967.05818235452 340779.1156509985 312872.5179120541 320399.0086000143 331879.58487759356 280047.89079067 396487.6620716235 411050.9219868998 334902.1114965111 333487.790140766 0.7675455166568773 1.0218638454713882 0.9381828275631615 0.9607518418133782 0.9951776187593147 0.8397545549492564 1.188912079522507 1.2325816240930267 1.0042409989137775 1.0 18.347274415979115 -7.2665342231288195 24.983713706198433 1.1258154812285406 0.9311729423769285 0.4611203710926881 0.0971425971552187 366.99191712221426 1799617.9048431183 0.03845422676000724 0.02682250374529403 5.413345881343326e-08 7.2665342231288195 -0.1946425388516121 VSS(ph)PTVNTTLR ddPTM_PC-9_AZD4547_30min_R2 1 VSSPTVNTTLR 11 0 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 VS(0.015)S(0.979)PT(0.005)VNTTLR 150.09 0.00032673 24006000.0 35398.0 37996.0 56823.0 72761.0 59384.0 51581.0 38013.0 57023.0 38731.0 44860.0 True False 46653.82767586063 50277.463947722885 56069.489892511374 55987.07559624386 51139.55664245416 48355.631915921964 41396.08335906134 48211.4056081827 40778.24158909637 43289.46505432132 1.077717814653463 1.1614249306299522 1.2952225171217333 1.2933187214484883 1.1813395378825364 1.1170300177016144 0.9562622986242937 1.1136983454908749 0.941989963099018 1.0 15.4017283522354 -6.9546092418446355 2.7396664335524368 1.0125529362540016 1.210929765768693 0.6161048774753837 0.07346040378121473 0.19694172373533847 3.0014649452685043 0.030703649789266662 0.025411397408032586 1.1101732487369571e-07 6.9546092418446355 0.1983768295146915 VSS(ph)PTVNTTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSSPTVNTTLR 11 0 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 VS(0.313)S(0.628)PT(0.043)VNT(0.013)T(0.003)LR;VS(0.14)S(0.859)PT(0.001)VNTTLR 101.71 0.0036201000000000002 2960600.0 41897.0 36891.0 42590.0 47847.0 54524.0 55422.0 53701.0 38613.0 41803.0 26110.5 True False 48989.334596530345 40553.294675874626 43605.507123474476 45166.28771206699 43840.413603808964 52515.57275514503 48614.05251842842 37599.44966385532 42414.289791493815 30844.126959395708 1.5882872827304084 1.3147817323298017 1.4137377654059815 1.4643399624027444 1.4213536879005206 1.7026117427242593 1.5761202313304463 1.219014878046396 1.3751172094230282 1.0 14.912708191025356 -8.634559057107632 1.097243981759182 1.0086968065564321 1.481121244951399 0.5660311923946916 0.12549351787456856 0.4979267459400975 1.2665098070332257 0.12467667099683684 0.039724679036491746 2.3197487153750087e-09 8.634559057107632 0.47242443839496695 VSS(ph)PVFGATSSIK ddPTM_PC-9_AZD4547_30min_R2 2 VSSPVFGATSSIK 13 0 F6Q6H0;I6L8A6;Q99708-3;Q99708;Q99708-2 F6Q6H0 RBBP8 DNA endonuclease RBBP8 1 VS(0.046)S(0.954)PVFGATSSIK;VS(0.239)S(0.761)PVFGATSSIK 193.51 1.4300999999999999e-06 116248000.0 481560.0 419150.0 628190.0 804720.0 725710.0 618920.0 556110.0 651020.0 547220.0 631210.0 True False 634686.0629297527 554632.0405750085 619859.790147946 619204.2368000627 624957.6931664326 580218.834559283 605602.71267218 550419.8179513364 576144.9320282285 609111.5300253714 1.0419866176286567 0.9105590901421721 1.0176457998129291 1.0165695546335676 1.0260152079872813 0.9525658372205089 0.9942394501167213 0.9036437348812125 0.9458775669608985 1.0 19.216346888254208 -7.22839699238973 1.836279851561352 0.9480319257486313 0.9972739263866645 0.16195727624467915 0.04281908262750458 0.5978763189234452 3.940839872792618 0.02189138314837768 0.014039575085938746 5.910211295820358e-08 7.22839699238973 0.04924200063803319 VSS(ph)PVFGATSSIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSSPVFGATSSIK 13 0 F6Q6H0;I6L8A6;Q99708-3;Q99708;Q99708-2 F6Q6H0 RBBP8 DNA endonuclease RBBP8 1 VS(0.275)S(0.721)PVFGAT(0.002)S(0.002)SIK 92.295 0.0046887 8195100.0 66445.0 73783.0 76069.0 75964.0 100830.0 78524.0 78750.0 70713.0 74877.0 57084.0 True False 77692.82615142988 81107.68862514028 77882.77345328913 71707.98335861079 81073.08531421148 74406.06320639826 71290.22989937298 68856.85867661652 75971.93447163314 67432.87732330467 1.1521505419223657 1.2027914549200116 1.154967377113137 1.0633979477816031 1.2022783029932016 1.1034092887607463 1.0572028471745964 1.0211170190244832 1.126630472957401 1.0 16.04116453752241 -6.693131477203352 0.2310502849182151 0.9881864939706004 1.2388191891529088 0.5113308721642496 0.0475034253039548 3.500493952263319 0.40975768564127524 0.10867407183252178 0.2776281296868889 2.0270689569375414e-07 6.693131477203352 0.25063269518230835 VSS(ph)QAEDTSSSFDNLFIDR ddPTM_PC-9_AZD4547_30min_R2 2 VSSQAEDTSSSFDNLFIDR 19 0 H8Y6P7;P0CAP2-3;P0CAP2;Q9BZD3 H8Y6P7 GCOM1;POLR2M;GCOM2 DNA-directed RNA polymerase II subunit GRINL1A;Putative GRINL1B complex locus protein 2 1 VS(0.001)S(0.999)QAEDTSSSFDNLFIDR;VS(0.004)S(0.996)QAEDTSSSFDNLFIDR 224.99 3.9594999999999995e-35 9221600.0 10961.5 13759.0 15023.4 16846.7 13445.9 15261.4 11709.4 16688.9 13929.8 12634.7 True False 14447.028986636144 18206.327678090303 14824.179899884819 12962.953593920396 11579.168878128368 14307.102245432456 12751.513915886477 14110.013977770368 14666.100789749667 12192.362998703382 1.1849244472275422 1.4932566951973532 1.2158578202979458 1.0632027274203502 0.9497067040539865 1.1734478580529442 1.0458607504749127 1.1572829630540793 1.2028924000465997 1.0 13.573690140957334 -5.5397787731391315 4.835001501470113 1.0894607735841204 1.3443201654753656 0.5058194310971376 0.10132675612966534 0.13561992467416054 8.452438169265003 0.0269442835750143 0.050838619208210166 2.8855009847647123e-06 5.5397787731391315 0.2548593918912452 VSS(ph)QAEDTSSSFDNLFIDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSSQAEDTSSSFDNLFIDR 19 0 H8Y6P7;P0CAP2-3;P0CAP2;Q9BZD3 H8Y6P7 GCOM1;POLR2M;GCOM2 DNA-directed RNA polymerase II subunit GRINL1A;Putative GRINL1B complex locus protein 2 1 VS(0.028)S(0.972)QAEDTSSSFDNLFIDR;VS(0.056)S(0.944)QAEDTSSSFDNLFIDR 163.11 7.702100000000001e-21 2038700.0 913.0 3181.89 1817.97 2070.41 6162.5 8330.0 12571.1 9298.9 8560.3 8243.6 True False 1067.5528674280308 3497.767010821572 1861.317299489619 1954.4116400597864 4955.002362876395 7893.160135873086 11380.274401117586 9054.81372799896 8685.478193003477 9738.099423698304 0.10962640870456414 0.35918374403834147 0.1911376356417127 0.2006974415668418 0.5088264298080661 0.8105442132439686 1.1686340327788132 0.929833772898588 0.8919069127459097 1.0 13.249424514920417 -6.672417342551096 2.0851395848118432 0.992807573368076 0.22365294870261224 0.934562472719688 0.09406461436228172 0.07375664405488565 0.6576187726039356 0.03633807296972426 0.03548328544999013 2.1260949574560246e-07 6.672417342551096 -0.7691546246654638 down VSS(ph)QAEDTSSSFDNLFIDR ddPTM_PC-9_Lapatinib_30min_R1 3 VSSQAEDTSSSFDNLFIDR 19 0 H8Y6P7;P0CAP2-3;P0CAP2;Q9BZD3 H8Y6P7 GCOM1;POLR2M;GCOM2 DNA-directed RNA polymerase II subunit GRINL1A;Putative GRINL1B complex locus protein 2 1 VS(0.03)S(0.97)QAEDTSSSFDNLFIDR;VS(0.034)S(0.965)QAEDTSSSFDNLFIDR;VS(0.005)S(0.995)QAEDTSSSFDNLFIDR 165.17 9.6704e-08 5649700.0 7303.1900000000005 8107.150000000001 9586.6 8896.81 24389.899999999998 36883.6 46159.2 43521.9 42519.3 37769.8 True False 7199.045171358977 8088.37839227681 8798.426753346144 9551.111086288129 22955.334034388336 35306.17440787102 48549.09751729981 45544.08635850735 37730.328685921435 44298.25960490501 0.16251304759074212 0.182589078316323 0.19861788774139383 0.21560917226713266 0.5181994561214446 0.7970104180788554 1.0959594790022882 1.0281236049613198 0.8517338835077771 1.0 15.434962398675216 -6.635436664854168 1.6965820444520157 0.9977676670309278 0.17871844373942217 0.9703914642081035 0.06374486256934671 0.05621775712386312 0.33297186668738427 0.02662863183430518 0.026738426670054938 2.31506577800361e-07 6.635436664854168 -0.8190492232915056 down VSS(ph)SPGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSSSPGVK 8 0 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 VS(0.024)S(0.614)S(0.362)PGVK 106.18 0.0038301999999999998 28346000.0 45234.0 52268.0 55843.0 54508.0 60096.0 50179.0 47780.0 46099.0 45074.0 41581.0 True False 52891.22278777605 57456.821612821965 57174.508905756855 51454.093477320355 48320.62020274563 47547.52490491905 43253.93250275617 44888.95009592795 45733.121978369745 49119.306144985116 1.0767909186595062 1.1697400904488973 1.163992600730052 1.047532986835027 0.9837398773532752 0.9680007442404287 0.8805892407169563 0.9138758997008131 0.9310620521262984 1.0 15.584002561017737 -6.2007703935988685 1.6101387761168588 0.9294182120840343 1.1411729393360142 0.8240576826040911 0.03973707211770674 0.14215182140196786 0.732186504580808 0.014251561727931454 0.02025528061723829 6.298390833886093e-07 6.2007703935988685 0.21175472725197986 VSS(ph)SPGVK ddPTM_PC-9_Lapatinib_30min_R1 1 VSSSPGVK 8 0 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 VS(0.024)S(0.615)S(0.361)PGVK 112.11 0.0037351999999999997 39627000.0 118500.0 148200.0 159990.0 125470.0 133340.0 130300.0 128950.0 139620.0 146940.0 115270.0 True False 116810.16826976168 147856.85200538093 146836.23977925946 134697.48235565017 125497.20335652644 124727.3727441353 135626.4000428041 146107.25490786953 130390.06985320307 135194.26591238 0.8640171791418051 1.0936621535502666 1.086112926375329 0.996325409562475 0.928273122455221 0.9225788675458443 1.0031963939262347 1.0807207977486433 0.9644644983516493 1.0 17.044674437334976 -10.715164783192717 7.74368950331865 1.0000000011629462 0.9979095210922478 0.0 0.0730795726994159 1.5207088882744665e-09 2.104248488914152e-10 0.07290097285659379 0.0176810731374555 1.9267936963034684e-11 10.715164783192717 -0.0020904800706983417 VSSDNVADLHEK ddPTM_PC-9_Lapatinib_30min_R1 1 VSSDNVADLHEK 12 0 P28074;P28074-3 P28074 PSMB5 Proteasome subunit beta type-5 0 87.863 0.0070059 5840800.0 52305.0 45722.0 57022.0 40938.0 51456.0 45074.0 48883.0 45775.0 50249.0 54000.0 False True 51559.12110843777 45616.133518151306 52333.87127128533 43948.71708516462 48429.459246388324 43146.290092625924 51413.92255364402 47901.873609853275 44589.42847457192 63333.82804952287 0.8140850268536105 0.7202491136724359 0.8263178286075444 0.6939216914347831 0.76466969924066 0.6812518905203137 0.811792436001843 0.7563394647864515 0.7040381080345551 1.0 15.950688661563548 -11.526484245893068 2.4859112810193738 1.2530220501572604 0.7521334667403411 0.6895392055432883 0.04981760864306141 6738075.319674048 2699097.3474039836 9753420.721121356 0.011600373434160283 2.9751971827122557e-12 11.526484245893068 -0.5008885834169193 VSSGYVPPPVAT(ph)PFSSK ddPTM_PC-9_AZD4547_30min_R2 2 VSSGYVPPPVATPFSSK 17 0 Q15942;Q15942-2;H7C3R3 Q15942 ZYX Zyxin 1 VSSGYVPPPVAT(0.963)PFS(0.03)S(0.007)K;VSSGYVPPPVAT(0.996)PFS(0.003)S(0.001)K 131.18 6.5064e-05 12212800.0 54635.0 57400.0 59872.0 86939.0 71538.0 88647.0 61925.0 102966.0 82575.0 81062.0 True False 72007.79352140352 75953.42748182171 59078.05816033015 66896.55674416032 61606.183535765274 83103.88907641816 67436.2050353792 87054.97062329475 86939.7459197963 78224.04405335264 0.9205327389145296 0.9709729073840485 0.7552416763321007 0.8551917451178257 0.7875607082362915 1.0623829294703457 0.8620904972566286 1.1128927387584178 1.111419729980965 1.0 16.255324502489415 -7.419745057163339 1.263200176570975 1.0784659731769626 0.8674697760447753 0.4294678786164453 0.09241113357465776 0.4323344220934454 1.3151711591717021 0.06519414029552728 0.03280651185678258 3.804126434997377e-08 7.419745057163339 -0.2109961971321873 VSSPLS(ph)PLSPGIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSSPLSPLSPGIK 13 0 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 VS(0.001)S(0.004)PLS(0.524)PLS(0.472)PGIK 163.33 0.00034487 7450600.0 48492.0 51957.0 51936.0 44980.0 79471.0 89188.0 100950.0 99743.0 82468.0 77054.0 True False 56700.73783934294 57114.947588149385 53174.35120837685 42459.91642712757 63899.228037346846 84510.82427349915 91387.28518529164 97124.85193644433 83673.93848587187 91023.28024087174 0.6229256701065677 0.6274762614246387 0.5841840798053357 0.4664731518658455 0.7020097261739254 0.9284528534882626 1.0039990312748195 1.0670330895505657 0.9192586584931727 1.0 16.47394795774707 -6.717576364275749 2.7059223518699693 0.9995913419471533 0.5790330381770172 0.9272865226090881 0.054705436809249636 0.06721472796713836 1.0062228364547037 0.020707634302794743 0.019713413496613215 1.9161241109636296e-07 6.717576364275749 -0.42055830377013603 VSSPLSPLS(ph)PGIK ddPTM_PC-9_AZD4547_30min_R2 2 VSSPLSPLSPGIK 13 0 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 VSSPLS(0.002)PLS(0.998)PGIK;VSSPLS(0.015)PLS(0.985)PGIK 188.12 3.0303e-05 36310000.0 239360.0 206522.0 239842.0 307170.0 216309.0 225270.0 174590.0 240655.0 193577.0 223440.0 True False 315471.5010027119 273276.1977421737 236661.53837002092 236356.70222919178 186278.22911512534 211183.83128864755 190128.17177435366 203467.2994517509 203809.08502472207 215617.43360984264 1.463107577718201 1.2674123477263157 1.0975992729709294 1.096185490533556 0.863929349294611 0.9794376445031915 0.8817847823863282 0.9436495743656922 0.945234722501671 1.0 17.718114305429076 -4.875983047324121 0.8059389893700822 0.9301284083729148 1.7248566135055832 0.9161591567212576 0.05137924366173466 0.5581145892650596 0.30546427681779925 0.019153117241596674 0.38854188959621544 1.3305063532516838e-05 4.875983047324121 0.7947282051326684 VSSPLSPLSPGIKS(ph)PTIPR ddPTM_PC-9_AZD4547_30min_R2 3 VSSPLSPLSPGIKSPTIPR 19 1 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 VSSPLS(0.006)PLS(0.134)PGIKS(0.826)PT(0.033)IPR;VSSPLSPLS(0.012)PGIKS(0.981)PT(0.007)IPR;VSSPLSPLSPGIKS(0.999)PT(0.001)IPR 145.8 3.8994e-05 101205000.0 62943.0 74585.2 153130.0 281012.0 222160.0 144853.0 111856.0 179500.0 151001.0 163351.0 True False 82957.5647042683 98693.40730691912 151099.3961466354 216229.0249921205 191316.91876073743 135795.3190112068 121810.96730621558 151762.39949965474 158982.60458534874 157632.13121017473 0.5262731910517594 0.6260995556504201 0.9585570846921491 1.3717319136148525 1.2136923943865858 0.8614697902558179 0.7727546812381929 0.9627631012442905 1.0085672468221176 1.0 17.266202113373083 -5.251812916899582 3.8409139563450245 1.0256176508976669 0.5564059044114195 0.5575141024704705 0.1592784509845085 0.17856226490045038 6.038754458453334 0.048230742755930665 0.13036005645359405 5.599987828842275e-06 5.251812916899582 -0.4692117464862474 VSSPLSPLSPGIKS(ph)PTIPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSSPLSPLSPGIKSPTIPR 19 1 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 VS(0.004)S(0.014)PLS(0.059)PLS(0.001)PGIKS(0.875)PT(0.048)IPR;VSSPLSPLS(0.01)PGIKS(0.972)PT(0.019)IPR 111.6 5.8339e-05 72953900.0 38029.0 30885.3 54654.5 54963.0 71070.0 64957.0 58216.0 49474.0 56060.0 47669.2 True False 44466.55859301272 33951.38847016319 55957.670558345475 51883.60130245026 57144.34368026374 61550.54056973689 52701.35903265911 48175.359922036005 56879.77144489969 56311.24861082041 0.7896567682299325 0.6029237374011861 0.9937210049288981 0.9213718854119075 1.0147944698438678 1.0930416584282547 0.9358939880180946 0.8555192987281574 1.01009607934657 1.0 15.781135520222154 -5.2709842477457185 24.92553276051741 0.9747834540878951 0.696290251571936 0.7021368798617039 0.07338332433180271 306.0036102433506 799101.026001007 0.019566329579472286 0.04158275792662509 5.358160916959278e-06 5.2709842477457185 -0.2784932025159591 VSSPLSPLSPGIKS(ph)PTIPR ddPTM_PC-9_Lapatinib_30min_R1 1 VSSPLSPLSPGIKSPTIPR 19 1 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 VSSPLSPLS(0.008)PGIKS(0.854)PT(0.138)IPR 96.016 0.00032089 109490000.0 36619.0 27885.0 42254.0 30625.0 33831.0 21404.0 22027.0 21116.0 40544.0 15365.0 True False 36096.806344897865 27820.43399574928 38780.039225156805 32877.26466200515 31841.1270943051 20488.60081516098 23167.450281061243 22097.126447747924 35977.50777275258 18020.819777424436 2.0030612808257535 1.5437940304248146 2.1519575526601993 1.8244044981345473 1.766907803727888 1.1369405536604973 1.2855935838215442 1.2261998466590336 1.9964412394725441 1.0 14.137377021218319 -6.638910132666267 5.719532331321014 1.3422776945078247 1.8662055057942168 0.4652384510776648 0.28493788726951313 0.19852509052916475 9.187753882894311 0.09275841378429801 0.09248237163791971 2.2966238328464883e-07 6.638910132666267 0.5239278112863921 VSSPLSPLSPGIKSPT(ph)IPR ddPTM_PC-9_Lapatinib_30min_R1 1 VSSPLSPLSPGIKSPTIPR 19 1 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 VSSPLSPLSPGIKS(0.357)PT(0.643)IPR 144.3 5.4945e-05 77194000.0 212460.0 156650.0 133500.0 117670.0 132270.0 114370.0 86479.0 100460.0 135870.0 88118.0 True False 209430.28143960793 156287.28654954737 122524.14532490261 126323.84433561284 124490.13865282542 109478.66170949182 90956.45947500321 105127.73834726063 120566.88982547101 103349.07889014535 2.0264358781776983 1.5122271841016848 1.1855368876111547 1.2223025661398343 1.2045597308627387 1.0593095060466082 0.8800896965098756 1.0172102110267078 1.1665985911072057 1.0 16.657166005081727 -1.522878745280439 0.6160262623485124 1.0325775712677427 71.69318101927132 0.9254755536806485 0.08503816017012615 47.924080985606864 0.3507545038855098 0.04073075008349746 4579.042457161153 0.029999999999992987 1.522878745280439 70.66060344800358 up VSSPSCDSQGLHAEEAPS(ph)SEPQSPVAQTSGWPACSTPLPLVSR ddPTM_PC-9_AZD4547_30min_R2 1 VSSPSCDSQGLHAEEAPSSEPQSPVAQTSGWPACSTPLPLVSR 43 0 K7ENW4;Q96RE7 K7ENW4 NACC1 Nucleus accumbens-associated protein 1 1 VSSPSCDSQGLHAEEAPS(0.316)S(0.316)EPQS(0.316)PVAQT(0.039)S(0.013)GWPACSTPLPLVSR 83.491 3.928e-13 6155300.0 7124.1 6515.5 20070.0 38926.0 34468.0 26442.0 18144.0 37517.0 20896.0 30240.0 True False 9389.415609514625 8621.50795745311 19803.858686494947 29952.21210070493 29682.713160987983 24788.577559969915 19758.78085041456 31719.609704894337 22000.51989997052 29181.306804339652 0.32176131358580184 0.29544626000679913 0.6786487945615186 1.0264177783926605 1.0171824503957363 0.8494676995165796 0.6771040441367816 1.0869838666778695 0.7539251085458156 1.0 14.8327568713702 -5.424056937657374 3.124319246706435 0.9099433879465195 0.3049243511207011 0.7921547412382606 0.1231682989425177 0.10794692654878155 1.9879490367205892 0.03389428190978591 0.07962004046609797 3.7665441492126326e-06 5.424056937657374 -0.6050190368258184 down VSSPSCDSQGLHAEEAPSSEPQS(ph)PVAQTSGWPACSTPLPLVSR ddPTM_PC-9_AZD4547_30min_R2 1 VSSPSCDSQGLHAEEAPSSEPQSPVAQTSGWPACSTPLPLVSR 43 0 K7ENW4;Q96RE7 K7ENW4 NACC1 Nucleus accumbens-associated protein 1 1 VSSPSCDSQGLHAEEAPS(0.008)S(0.025)EPQS(0.967)PVAQTSGWPACSTPLPLVSR 107.66 5.261e-31 5476800.0 8305.8 8174.5 20470.0 33218.0 23800.0 20251.0 11409.0 25972.0 16442.0 19940.0 True False 10946.871628627698 10816.747263939911 20198.554425139595 25560.103312984036 20495.78081790397 18984.701768661627 12424.3788978384 21958.624177186754 17311.09055299172 19241.90666926363 0.5689078435305925 0.5621452930762946 1.0497168899277576 1.3283560591120047 1.0651637163713739 0.9866330865738553 0.6456937512166964 1.1411875420985549 0.8996556760481471 1.0 14.231964141547323 -5.259248816619822 24.453105504574864 1.0184376629553995 0.5655264979472948 0.5454817367555838 0.1639207733750296 107.47953186990006 1199757.0243014884 0.04516562438042269 0.10809371994897132 5.504922172480018e-06 5.259248816619822 -0.4529111650081047 VSSS(ph)PGVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VSSSPGVK 8 0 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 VS(0.001)S(0.02)S(0.979)PGVK;VSS(0.027)S(0.973)PGVK;VS(0.001)S(0.026)S(0.972)PGVK;VS(0.002)S(0.04)S(0.959)PGVK 126.31 0.003513 55896500.0 384614.0 416238.0 433198.0 515521.0 561897.0 421761.0 454564.0 389279.0 405571.0 338713.0 True False 449721.5537272341 457559.35781889025 443527.0832325647 486638.0297116326 451797.3164613642 399643.1106921927 411504.4071616327 379060.83872519416 411501.70861004974 400118.98564936646 1.123969543703021 1.1435582270016553 1.1084879726783017 1.2162332885100453 1.1291574073350388 0.998810666391145 1.028455089412437 0.9473702881406731 1.0284483450396884 1.0 18.610069560636795 -6.734270202489587 4.960581526040712 0.9983194800658721 1.1478214547741583 0.8206624030778937 0.03363613239339002 0.07513874106763692 4.609471868616398 0.011384013776108181 0.010950643538348868 1.8438678736097163e-07 6.734270202489587 0.1495019747082862 VSSS(ph)PGVK ddPTM_PC-9_Lapatinib_30min_R1 1 VSSSPGVK 8 0 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 VS(0.001)S(0.028)S(0.971)PGVK 104.42 0.0038583 37502000.0 75073.0 98495.0 88025.0 86693.0 91242.0 74358.0 71034.0 77587.0 82751.0 56669.0 True False 74002.44525329799 98266.94087901479 80787.92428632628 93068.69241937003 85875.32494867401 71177.88167696413 74711.79294796857 81191.97526526892 73430.71097333885 66464.16114330397 1.113418780592757 1.4784951647421016 1.2155110799057363 1.4002838645432354 1.292054597116143 1.0709212371385666 1.1240914150241332 1.2215903107572543 1.1048166366685084 1.0 16.020288998683533 -6.709861056934774 7.119345197601729 1.1195239353626203 1.3118658826344975 0.4565292156500783 0.10575450557290679 0.19511872026312133 21.641674451355602 0.03302672024934796 0.03277160147892584 1.9504685098890204e-07 6.709861056934774 0.19234194727187726 VSSS(ph)PQKEGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSSSPQKEGR 10 1 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 VS(0.004)S(0.127)S(0.868)PQKEGR;VS(0.058)S(0.298)S(0.644)PQKEGR 117.25 0.004693800000000001 10272000.0 40420.0 25675.0 32670.0 41922.0 55093.0 51462.0 42895.0 49273.0 44156.0 40327.0 True False 47262.307668610076 28223.844319836306 33448.976701664935 39573.24625295779 44297.92213840963 48763.242126326644 38831.675067093456 47979.635959058935 44801.69796505513 47637.96587164363 0.9921143105890429 0.592465354122865 0.7021495584381227 0.8307081448352449 0.9298869363517019 1.0236214169537585 0.8151413343659979 1.007172222431493 0.9404620274041385 1.0 15.539824191375631 -6.1125112401151105 2.9472243194043743 0.9505680097225975 0.7468242155634267 0.3902808471488115 0.10784244472261902 0.25779699761554936 4.3041344397391965 0.03256519025540051 0.04479862402717669 7.717715408591562e-07 6.1125112401151105 -0.20374379415917077 VSSSS(ph)PQSGCPSPTIPAGK ddPTM_PC-9_AZD4547_30min_R2 1 VSSSSPQSGCPSPTIPAGK 19 0 E7EWD6;Q76L83;A0A5F9ZHC8 E7EWD6 ASXL2 Putative Polycomb group protein ASXL2 1 VS(0.027)S(0.022)S(0.107)S(0.819)PQS(0.022)GCPS(0.002)PTIPAGK 90.444 0.00099683 4453900.0 16649.0 17545.0 17423.0 27281.0 22853.0 23095.0 18989.0 27431.0 16990.0 24153.0 True False 21943.035679287063 23216.078138825087 17191.959636014024 20991.786937248402 19680.255421494083 21650.86599907363 20678.984213432657 23192.169251671414 17888.056714227558 23307.410821601035 0.9414617456757794 0.9960813887276015 0.7376177374485852 0.9006486004783276 0.8443775918367841 0.9289262614707877 0.8872278594869756 0.9950555825007033 0.7674836493485203 1.0 14.508501126516974 -6.796528632762148 24.92497144997695 0.9136477135810045 0.8830503844499044 0.03186412987329401 0.08690407074839664 841.9677621720098 598069.963983939 0.030163110106210162 0.026602506148367403 1.5976121960187543e-07 6.796528632762148 -0.030597329131100137 VSSSS(ph)PQSGCPSPTIPAGK ddPTM_PC-9_Lapatinib_30min_R1 2 VSSSSPQSGCPSPTIPAGK 19 0 E7EWD6;Q76L83;A0A5F9ZHC8 E7EWD6 ASXL2 Putative Polycomb group protein ASXL2 1 VS(0.046)S(0.242)S(0.114)S(0.597)PQSGCPSPTIPAGK;VS(0.068)S(0.045)S(0.342)S(0.545)PQSGCPSPTIPAGK 230.48 7.7236e-102 6582800.0 37352.0 31749.0 43346.0 38862.0 42310.0 35582.0 36685.0 33405.0 39096.0 30257.0 True False 36819.3536304821 31675.487141152735 39782.2592003987 41720.041119831665 39821.40898466048 34060.240805693225 38584.369798916436 34957.11825094809 34692.59678086856 35486.88213508172 1.0375482830621268 0.8925970734926553 1.121041263894825 1.1756468477851412 1.1221444823774394 0.9597980649875649 1.0872854271063894 0.985071557368239 0.9776174939463632 1.0 15.114998204840052 -7.778120878512072 24.005261616063787 0.9860083120148078 1.0561312295770096 0.14185344725680127 0.07775699864126973 347.8179653032176 500510.5807387668 0.046021170845762654 0.022215815051892688 1.6667832271069214e-08 7.778120878512072 0.07012291756220179 VSSSSPQSGCPS(ph)PTIPAGK ddPTM_PC-9_AZD4547_30min_R2 2 VSSSSPQSGCPSPTIPAGK 19 0 E7EWD6;Q76L83;A0A5F9ZHC8 E7EWD6 ASXL2 Putative Polycomb group protein ASXL2 1 VSSSSPQSGCPS(0.516)PT(0.484)IPAGK;VSSSSPQS(0.001)GCPS(0.677)PT(0.322)IPAGK 145.71 4.2720999999999997e-14 0.0 17256.9 16954.4 21938.0 31325.0 22310.0 23468.0 19636.1 24267.0 21516.0 22647.3 True False 22744.235234181568 22434.57823863756 21647.087785965432 24103.50521642557 19212.641598631828 22000.54225010868 21383.674859833867 20517.09275018447 22653.291834215426 21854.424920301637 1.0407153387529013 1.0265462633060178 0.9905128075850854 1.1029118956149997 0.8791190648436725 1.0066859379892128 0.9784597370013398 0.938807258713321 1.036554012142945 1.0 14.415637794939341 -6.246472554622185 24.97615028725347 0.9721415412133937 1.035651275044854 0.3204174044951017 0.04753175394323854 1014.6945010455685 1693289.4036787678 0.013427957170394151 0.01726273325562509 5.669273975482325e-07 6.246472554622185 0.06350973383146041 VSSSSPQSGCPSPT(ph)IPAGK ddPTM_PC-9_Lapatinib_30min_R1 1 VSSSSPQSGCPSPTIPAGK 19 0 E7EWD6;Q76L83;A0A5F9ZHC8 E7EWD6 ASXL2 Putative Polycomb group protein ASXL2 1 VSSSSPQSGCPS(0.114)PT(0.886)IPAGK 87.323 0.004594600000000001 0.0 5646.0 7650.0 7085.1 6012.1 8908.8 9539.8 7653.6 7335.0 8123.9 6954.9 True False 5565.487004650405 7632.286895014599 6502.590427276905 6454.24988977767 8384.801899374694 9131.804992359957 8049.865958647584 7675.810877734 7208.900833540463 8157.045198178277 0.6822920395112377 0.9356680893124298 0.7971747451796806 0.7912485137656349 1.0279214710306228 1.1194991287285467 0.9868605313656188 0.941003842843515 0.8837637475823275 1.0 12.993830930739664 -6.259168525974841 24.97697482937116 0.9962254861485264 0.8108566356623687 0.5755045973686977 0.08042293247690901 160.6435869248935 1766907.7487394202 0.02520807412179405 0.031003639522813195 5.505939994786682e-07 6.259168525974841 -0.1853688504861577 VSTET(ph)SSPLSPPAVPPPPVPVLPGAVPSQTER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSTETSSPLSPPAVPPPPVPVLPGAVPSQTER 32 0 E9PNR2;Q13671-2;Q13671 E9PNR2 RIN1 Ras and Rab interactor 1 1 VS(0.044)T(0.044)ET(0.316)S(0.276)S(0.241)PLS(0.079)PPAVPPPPVPVLPGAVPSQTER 56.00899999999999 0.0028587 3649700.0 3109.9 3567.7 3717.5 3290.4 6944.8 6992.7 11142.0 9018.9 9671.7 8719.7 True False 3636.3446466751743 3921.8776778921087 3806.139298697259 3106.0495556207334 5584.016293663936 6625.990502055188 10086.549098905596 8782.163431314442 9813.13031544125 10300.512584892787 0.35302560107624226 0.3807458750785002 0.369509698408555 0.30154320282819813 0.5421105258250658 0.6432680361726051 0.9792278797561007 0.852594796514765 0.9526836877840085 1.0 13.330428511645572 -6.893385038281975 1.498386691248571 0.946276452259506 0.3542026924384372 0.955919985702082 0.05689893402749858 0.07170687020181656 0.33185587740795225 0.02604772614649965 0.02113588754628101 1.2782475285879283e-07 6.893385038281975 -0.5920737598210688 down VSTETSS(ph)PLSPPAVPPPPVPVLPGAVPSQTER ddPTM_PC-9_AZD4547_30min_R2 1 VSTETSSPLSPPAVPPPPVPVLPGAVPSQTER 32 0 E9PNR2;Q13671-2;Q13671 E9PNR2 RIN1 Ras and Rab interactor 1 1 VS(0.006)T(0.006)ET(0.046)S(0.134)S(0.404)PLS(0.404)PPAVPPPPVPVLPGAVPSQTER 77.032 3.3335999999999996e-07 7731200.0 11486.0 12721.0 17997.0 28370.0 20340.0 16419.0 14268.0 18837.0 13958.0 14698.0 True False 15138.309076358415 16832.814477286633 17758.348020969093 21829.734812130664 17516.14209395658 15392.317334435587 15537.824359221519 15926.174481197702 14695.791384178227 14183.427493723017 1.0673237539415623 1.18679455193296 1.2520491276758163 1.5391015198400795 1.234972442430328 1.0852325604123245 1.0954915069786835 1.1228720623591126 1.0361241237833352 1.0 13.791918588479342 -6.73169520975621 4.858881127455191 1.0762319394874413 1.2699598852317342 0.4020156845798809 0.11447738172550213 0.220231536498438 12.56844908577011 0.04249658744562485 0.040924440181505 1.8548328986179735e-07 6.73169520975621 0.19372794574429286 VSTETSSPLS(ph)PPAVPPPPVPVLPGAVPSQTER ddPTM_PC-9_AZD4547_30min_R2 3 VSTETSSPLSPPAVPPPPVPVLPGAVPSQTER 32 0 E9PNR2;Q13671-2;Q13671 E9PNR2 RIN1 Ras and Rab interactor 1 1 VSTETS(0.001)S(0.004)PLS(0.994)PPAVPPPPVPVLPGAVPSQTER;VS(0.048)T(0.048)ET(0.123)S(0.112)S(0.321)PLS(0.347)PPAVPPPPVPVLPGAVPSQTER;VSTET(0.003)S(0.008)S(0.024)PLS(0.964)PPAVPPPPVPVLPGAVPSQTER 111.01 3.0343e-16 16856500.0 34216.4 30724.6 44690.2 57245.1 47966.0 40329.3 33039.4 43048.0 29786.4 34181.6 True False 45096.50345466741 40655.72609769992 44097.578747942076 44048.12662297853 41306.7488534278 37807.50249562419 35979.84259420124 36395.92074463019 31360.848293859166 32984.912588069325 1.3671857802945597 1.2325552171511631 1.3369014888307515 1.3354022541478792 1.2522922030834331 1.1462059326268823 1.0907969665869355 1.103411162526307 0.9507634197946129 1.0 15.009518661243053 -7.1257249873721635 0.888337585333171 0.9954188050087397 1.3221830543711148 0.8912818012247055 0.0456504723934292 0.18569096897787796 0.29503747746542125 0.03376783385271058 0.022062513290712314 7.48643421385616e-08 7.1257249873721635 0.32676424936237514 VSTETSSPLS(ph)PPAVPPPPVPVLPGAVPSQTER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSTETSSPLSPPAVPPPPVPVLPGAVPSQTER 32 0 E9PNR2;Q13671-2;Q13671 E9PNR2 RIN1 Ras and Rab interactor 1 1 VS(0.014)T(0.014)ET(0.04)S(0.112)S(0.378)PLS(0.441)PPAVPPPPVPVLPGAVPSQTER 83.124 4.1044e-08 4447100.0 5965.0 5925.4 7036.6 8141.5 11631.0 12863.0 17617.0 14192.0 13528.0 10313.0 True False 6974.756685879746 6513.634552395641 7204.379230454105 7685.358150099132 9351.989043832114 12188.441635982648 15948.190223965152 13819.47503766696 13725.82140753841 12182.665262336915 0.5725148426627481 0.534664165199773 0.591363143886639 0.6308437426955047 0.7676472136802508 1.0004741469556413 1.3090887651054053 1.1343556389413647 1.1266681889366368 1.0 13.572542172901493 -6.681455947451567 1.8729969329931542 1.1562458806411358 0.5758500969671995 0.9183178874373215 0.0760809052027616 0.08516588113369476 0.6149880561252837 0.030345532939135812 0.02943412981850315 2.0823036124363605e-07 6.681455947451567 -0.5803957836739363 VSTETSSPLS(ph)PPAVPPPPVPVLPGAVPSQTER ddPTM_PC-9_Lapatinib_30min_R1 1 VSTETSSPLSPPAVPPPPVPVLPGAVPSQTER 32 0 E9PNR2;Q13671-2;Q13671 E9PNR2 RIN1 Ras and Rab interactor 1 1 VS(0.027)T(0.027)ET(0.07)S(0.07)S(0.214)PLS(0.59)PPAVPPPPVPVLPGAVPSQTER 77.488 3.1146e-07 2924500.0 7068.1 4524.4 7464.5 3665.2 10327.0 13504.0 15939.0 15816.0 16298.0 12477.0 True False 6967.307597869203 4513.924029778305 6850.797623803261 3934.751034748777 9719.586163663178 12926.465399361512 16764.24342987403 16550.869099146672 14462.347614451493 14633.63282544253 0.47611605955806174 0.30846229939091024 0.4681542652821131 0.26888408925415197 0.6641950279608202 0.8833394655691457 1.145596833667109 1.1310157427464471 0.9882950998542731 1.0 13.837000345105505 -6.691568535274028 2.004522975520425 1.0728286030127057 0.381255503761473 0.9298798333263064 0.0847457893398488 0.0719916797051366 0.5946364922897439 0.03158107321599286 0.030432833918203877 2.0343771289207322e-07 6.691568535274028 -0.6915730992512327 down VSTEVDAR ddPTM_PC-9_AZD4547_30min_R2 1 VSTEVDAR 8 0 P37837;F2Z393 P37837 TALDO1 Transaldolase 0 116.9 0.016447999999999997 7085400.0 39935.0 43268.0 69998.0 79114.0 63043.0 62657.0 47874.0 73784.0 49259.0 63929.0 False True 52633.49930039814 57253.53484814385 69069.78078411928 60875.489599115404 54290.56765139162 58739.0478849949 52134.6932557731 62382.378187646245 51862.73017575839 61690.86516847316 0.8531814095435357 0.9280715174246416 1.1196111546741134 0.986782879975325 0.8800422477967867 0.9521514688533372 0.8450958357189048 1.0112093260045003 0.8406873535348408 1.0 15.912769258684046 -6.239374419684566 23.926050031267792 0.9198007639051198 0.9793302641127563 0.07976754759380933 0.08217650102575685 1137.1879849818067 1233102.9024392497 0.024419420207575388 0.03149177931265512 5.762694281706888e-07 6.239374419684566 0.05952950020763648 VSTEVDAR ddPTM_PC-9_Lapatinib_30min_R1 1 VSTEVDAR 8 0 P37837;F2Z393 P37837 TALDO1 Transaldolase 0 93.195 0.034125 13801000.0 64791.0 57096.0 71680.0 61597.0 69222.0 71560.0 64807.0 50091.0 70036.0 59517.0 False True 63867.06845878581 56963.79771996781 65786.74709280173 66127.04886156824 65150.4980556883 68499.54561450757 68162.38935691363 52418.41072618588 62147.80816822463 69804.43414858257 0.9149428576820958 0.8160484131812779 0.9424436698787791 0.9473187436891642 0.9333289331879961 0.9813065093931215 0.9764764973501001 0.7509323922690988 0.8903131860640773 1.0 16.09103106241684 -5.281865504084005 24.812962838180262 0.9234186750492231 0.8654956205666544 0.11034720064645631 0.06985682482149445 1625.1213768583427 1974140.8994303327 0.019311097798569554 0.040280167237426695 5.225579940355105e-06 5.281865504084005 -0.05792305448256874 VSTFSGRS(ph)PPAPPPYK ddPTM_PC-9_AZD4547_30min_R2 2 VSTFSGRSPPAPPPYK 16 1 A0A669KBI7;Q9UMN6 A0A669KBI7 KMT2B Histone-lysine N-methyltransferase 2B 1 VS(0.01)T(0.059)FS(0.277)GRS(0.653)PPAPPPYK;VST(0.004)FS(0.004)GRS(0.992)PPAPPPYK 94.71700000000001 0.0012087 4485000.0 51064.0 39309.0 59080.0 97741.0 74473.0 54163.0 50360.0 56947.0 47735.0 69174.0 True False 67301.28980281792 52014.86552060843 58296.56059781374 75208.32253339676 64133.709447553105 50776.17904775168 54841.942439752944 48147.14966187643 50258.17464706604 66752.23931492699 1.0082251995367615 0.7792227804555012 0.8733274148718722 1.1266786448702528 0.9607724041283461 0.7606663022673641 0.8215745719183583 0.7212814155151476 0.7529061970483949 1.0 16.02652861476688 -6.757084940463711 24.97790853512263 0.7945088329555228 0.9457726958058448 0.2770160626905097 0.11001681776342567 141.9968902516354 814521.4248831901 0.03782435422774624 0.03657972102192599 1.7495044824459034e-07 6.757084940463711 0.151263862850322 VSTFSGRS(ph)PPAPPPYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSTFSGRSPPAPPPYK 16 1 A0A669KBI7;Q9UMN6 A0A669KBI7 KMT2B Histone-lysine N-methyltransferase 2B 1 VS(0.002)T(0.01)FS(0.062)GRS(0.925)PPAPPPYK 86.944 0.0020580999999999998 4763300.0 15201.0 10144.0 13329.0 25571.0 22386.0 25505.0 23021.0 33616.0 29491.0 15720.0 True False 17774.229066564618 11151.029280639512 13646.813910513987 24138.33977230056 17999.623999245607 24167.472901013585 20840.284222393246 32733.615619096152 29922.250083509407 18569.91156054846 0.9571520579734877 0.6004890892603781 0.7348884708479964 1.2998629365355814 0.9692896996604755 1.3014317716168922 1.1222608225376887 1.762723290973464 1.611329703210803 1.0 14.180679323984766 -6.35143509454397 0.775625726510221 1.4511328736275573 0.7303209444239969 0.46387684907453053 0.2535441978544294 0.5723691736769104 0.7541093597625885 0.1493321595334564 0.23182894323511857 4.452099947314722e-07 6.35143509454397 -0.7208119292035604 VSTFSGRS(ph)PPAPPPYK ddPTM_PC-9_Lapatinib_30min_R1 1 VSTFSGRSPPAPPPYK 16 1 A0A669KBI7;Q9UMN6 A0A669KBI7 KMT2B Histone-lysine N-methyltransferase 2B 1 VS(0.006)T(0.029)FS(0.14)GRS(0.824)PPAPPPYK 69.979 0.0096975 3500600.0 30803.0 23162.0 26644.0 25564.0 23930.0 25365.0 24115.0 19295.0 34180.0 18310.0 True False 30363.74357142161 23108.369812069028 24453.433168814274 27444.061839004054 22522.484448190164 24280.19807870295 25363.556704398805 20191.516139860596 30330.288468643535 21474.85910345858 1.413920502348323 1.0760661898055186 1.1387005172423221 1.277962370173787 1.0487838052712932 1.1306336382338622 1.1810814023135519 0.9402397493080037 1.4123626293668565 1.0 14.390361045422692 -4.753907282651214 24.983260600836235 1.1354653843780744 1.413921001442523 0.2973738049411363 0.12907285196073565 327.75480314208284 1087041.529557294 0.029539944517488512 0.303574432973378 1.7623522501032235e-05 4.753907282651214 0.27845561706444855 VSTLPAITLK ddPTM_PC-9_Lapatinib_30min_R1 2 VSTLPAITLK 10 0 H7C1V0;H7C469;A0A1B0GW44;A0A1B0GV23;A0A1B0GVD5;A0A1B0GWE8;P07339;A0A1B0GU92;A0A1B0GU03 H7C1V0 CTSD Cathepsin D;Cathepsin D light chain;Cathepsin D heavy chain 0 ; 134.25 0.00051203 1921300.0 40419.7 39374.0 46158.0 40868.0 44575.0 47681.0 44304.0 38892.0 47915.0 44905.0 False True 39843.30766593484 39282.831922131336 42363.0674150326 43873.56905165148 41953.18613782183 45641.79477983975 46597.8443388631 40699.06430222641 42518.30813268152 52666.76941784861 0.7565170240427175 0.7458751003022126 0.8043604702413337 0.8330408251086473 0.7965779295284442 0.8666146658384534 0.8847674701511353 0.7727655360693838 0.8073080730535979 1.0 15.684605346772642 -14.522878745280336 0.15525189862770847 1.6649675649965485 0.7566989590800501 0.6833145719382315 0.040262147477064664 87.66008663585822 0.7917263174992294 18.11895422785027 0.20488195644457594 3.0000000000000132e-15 14.522878745280336 -0.9082686059164984 VSTS(ph)PLTK ddPTM_PC-9_AZD4547_30min_R2 1 VSTSPLTK 8 0 Q9Y320-2;Q9Y320 Q9Y320-2 TMX2 Thioredoxin-related transmembrane protein 2 1 VS(0.001)T(0.154)S(0.845)PLTK 86.882 0.012143000000000001 9786600.0 128300.0 116510.0 204400.0 181380.0 146950.0 93136.0 151540.0 168920.0 131330.0 129250.0 True False 169096.7311942174 154169.57902277051 201689.52244741237 139565.64329306522 126548.5290416379 87312.19119678391 165026.76642812064 142817.29539544054 138271.83568449126 124724.99684063828 1.35575654822644 1.2360760306913754 1.617073782772767 1.118986945907795 1.014620422907924 0.7000376300537663 1.3231250399547103 1.1450575186457521 1.1086136635558455 1.0 16.928391107238788 -5.92706740311149 8.38845872160114 1.0534310778827665 1.385457040043915 0.4647746644035704 0.17039057953423795 0.2588139505563602 26.586819668774098 0.049654090721323756 0.07382588061035994 1.182857960267272e-06 5.92706740311149 0.33202596216114855 VSTS(ph)PLTK ddPTM_PC-9_Lapatinib_30min_R1 2 VSTSPLTK 8 0 Q9Y320-2;Q9Y320 Q9Y320-2 TMX2 Thioredoxin-related transmembrane protein 2 1 VST(0.015)S(0.98)PLT(0.005)K;VST(0.008)S(0.99)PLT(0.001)K 86.898 0.01213 22523000.0 310730.0 468460.0 246310.0 162531.0 202636.0 221730.0 228602.0 183360.0 306780.0 100753.0 True False 306298.9332190964 467375.30965209607 226059.34258409572 174484.07192752152 190717.3488777042 212247.12477787546 240437.8930018232 191879.57498858974 272227.2058633839 118168.0218050664 2.592062797872478 3.9551758801809576 1.9130331466241364 1.4765760589218953 1.6139505930996916 1.7961468892828285 2.034712008621562 1.6237859622049033 2.3037299068309554 1.0 16.850480145949746 -5.362403347418176 6.3695327095222405 1.7335089412519067 3.263827060011737 0.6606835971277614 0.4463253138830938 0.11931997840800353 6.292046827344996 0.10866868200942129 0.22947590332252854 4.341068637223824e-06 5.362403347418176 1.5303181187598303 VSTTTDSPVS(ph)PAQAASPFIPLDELSSK ddPTM_PC-9_AZD4547_30min_R2 1 VSTTTDSPVSPAQAASPFIPLDELSSK 27 0 Q96E09 Q96E09 FAM122A Protein FAM122A 1 VS(0.013)T(0.013)T(0.013)T(0.035)DS(0.095)PVS(0.79)PAQAAS(0.04)PFIPLDELS(0.001)SK 56.292 0.0020647 4062900.0 12782.0 10761.0 13241.0 15052.0 13359.0 13085.0 14277.0 17348.0 11497.0 12451.0 True False 16846.41011788378 14239.282807175648 13065.415688484298 11581.993951081813 11504.33344312518 12266.79288148424 15547.625341786195 14667.265217381635 12104.707948409314 12015.094279789442 1.4021038641553636 1.1851161943129742 1.0874168262217965 0.9639536470857206 0.957490068344831 1.0209485332227628 1.2940077688727598 1.22073658981215 1.007458424089989 1.0 13.55256034857079 -4.811097221624776 2.2129696970838917 1.0758364531551454 1.4738043517767678 0.48822609104650705 0.10430344175115701 0.5874117663390559 3.5598626443534 0.03116107962182307 0.45670764073222786 1.5449085559519224e-05 4.811097221624776 0.3979678986216224 VSTVTS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 2 VSTVTSPSR 9 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 VS(0.004)T(0.003)VT(0.032)S(0.8)PS(0.161)R;VSTVT(0.095)S(0.866)PS(0.039)R 94.40899999999999 0.005756600000000001 43621000.0 234180.0 277070.0 378540.0 504760.0 398600.0 306240.0 284640.0 434160.0 287360.0 393210.0 True False 308644.3687534055 366627.4591008418 373520.31226635765 388395.38046426035 343261.2703368291 287090.7643886695 309972.4085792556 367070.5480042899 302549.26294293295 379443.8375838096 0.8134125216494884 0.9662232530522069 0.9843889273438428 1.0235912195529426 0.9046431548938025 0.7566093739109898 0.8169124857925529 0.9673909855584708 0.7973492595623125 1.0 18.53352683903566 -6.522052547747799 24.99995273228628 0.8589079050992805 0.9526059007510986 0.15501642861526876 0.08561713315102851 49.78879251055353 1506629.5854852814 0.027913311566549314 0.028250866044367395 3.005712602443241e-07 6.522052547747799 0.09369799565181813 VSTVTS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSTVTSPSR 9 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 VS(0.001)T(0.003)VT(0.099)S(0.885)PS(0.012)R 85.807 0.01215 15871000.0 71921.0 65839.0 92075.0 82231.0 100280.0 92256.0 103170.0 85529.0 79936.0 65822.0 True False 84095.80479549992 72375.06080520753 94270.4171963822 77623.86366649883 80630.85386600322 87417.93295259398 93396.99071388334 83283.9543754661 81104.91277594565 77755.0075533346 1.0815484100855624 0.9308089997362962 1.212403164281338 0.998313370534421 1.0369859948980906 1.1242739947344393 1.2011701066303597 1.0711072765099923 1.0430828229334714 1.0 16.2466479697731 -6.753668062541779 24.973850911989913 1.0994487496776957 1.0512058509253708 0.03562602492043376 0.08320721555830084 516.2870528608549 1659135.676409543 0.027471743704009965 0.02699203776793757 1.763323264583347e-07 6.753668062541779 -0.0482428987523249 VSTVTS(ph)PSR ddPTM_PC-9_Lapatinib_30min_R1 1 VSTVTSPSR 9 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 VS(0.001)T(0.004)VT(0.184)S(0.806)PS(0.005)R 93.556 0.0061653 16905000.0 125670.0 133240.0 128380.0 100560.0 107580.0 118980.0 99057.0 111720.0 132700.0 80474.0 True False 123877.92275494448 132931.49096624125 117825.09196113075 107955.51785832622 101252.3559104179 113891.50275592656 104185.68677037656 116910.91905391181 117753.92860705066 94383.82367513524 1.3124910385208228 1.4084139187217644 1.2483610789776782 1.1437925870634795 1.0727723455973115 1.2066845601417446 1.1038510913583972 1.238675384208991 1.2476071006865992 1.0 16.526251998634017 -5.51895356282689 3.4919916631258805 1.1532226352351438 1.3588047617455214 0.5672121347360153 0.07523784483263145 0.16654989161212758 4.2952867980608795 0.020447304707010516 0.04231919658070092 3.0272370997659766e-06 5.51895356282689 0.20558212651037766 VSVGAPDLSLEAS(ph)EGSIKLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSVGAPDLSLEASEGSIKLPK 21 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VSVGAPDLSLEAS(0.583)EGS(0.417)IKLPK 67.13600000000001 0.0017807000000000003 18483000.0 27789.0 22325.0 19190.0 25233.0 27371.0 20036.0 12642.0 22662.0 11625.0 10287.0 True False 32493.12884223172 24541.278459215016 19647.56237848027 23819.27681648977 22007.849034367526 18985.27688863782 11444.458239846024 22067.146512373776 11794.993632660697 12151.951668152798 2.673902080057479 2.0195339093992217 1.6168236111382486 1.9601194496941665 1.8110546877868638 1.5623232717748086 0.9417794402391398 1.8159343548251763 0.9706254562855448 1.0 13.568900416495588 -1.5228787452816053 0.21036748454681561 0.9952415265040147 8.55261521160645 0.7042902154775266 0.2839904543648858 30.11229745502251 0.3752311125240421 0.47872094095311063 76.1754577452545 0.02999999999991243 1.5228787452816053 7.557373685102436 up VSVGAPDLSLEASEGS(ph)IKLPK ddPTM_PC-9_AZD4547_30min_R2 2 VSVGAPDLSLEASEGSIKLPK 21 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VSVGAPDLSLEAS(0.016)EGS(0.984)IKLPK;VSVGAPDLS(0.001)LEAS(0.09)EGS(0.908)IKLPK 102.78 6.1237e-05 46456000.0 50336.0 50536.0 49847.0 59383.0 96709.0 66345.0 56508.0 75858.0 71447.0 73961.0 True False 66341.80094615863 66870.77371465745 49185.996210548765 45693.16680820427 83282.62466885184 62196.43666198486 61537.10252949882 64135.88914342493 75223.5425580586 71371.64790197647 0.9295259798018684 0.9369375050229942 0.689153153337611 0.6402145410872446 1.166886671626725 0.8714445930603555 0.8622065531401959 0.8986185835517024 1.0539695350928764 1.0 16.1230634628444 -6.2509299576032165 24.989444570573937 0.9595823826414253 0.8009703175078314 0.33139365785591846 0.12159097976851034 1020.5921411015121 2426776.950116086 0.03823419020216641 0.048833121265669674 5.611384683496738e-07 6.2509299576032165 -0.15861206513359383 VSVGAPDLSLEASEGS(ph)IKLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSVGAPDLSLEASEGSIKLPK 21 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VSVGAPDLSLEAS(0.029)EGS(0.971)IKLPK 101.85 7.421e-05 17190000.0 36473.0 24830.0 15458.0 27544.0 26472.0 20759.0 13703.0 28073.0 11049.0 8371.0 True False 42647.15852541356 27294.958304246764 15826.577344791449 26000.79897885287 21285.001630842024 19670.361495869063 12404.95263887124 27336.113495802183 11210.570722345643 9888.596035200457 4.312761728116143 2.7602460659819497 1.600487803167765 2.6293721460860335 2.152479639685326 1.989196588256658 1.2544705633351088 2.764407950177534 1.1336867925880834 1.0 13.27154998897964 -2.3712109752292023 0.8805193783746148 1.8369017821232756 199.9999996328614 0.6435273219545534 0.5708492844871379 91.38419262029423 1.1895091014465817 0.18366291753645725 35172.27742426381 0.004253917125644651 2.3712109752292023 198.16309785073813 VSVGAPDLSLEASEGS(ph)IKLPK ddPTM_PC-9_Lapatinib_30min_R1 2 VSVGAPDLSLEASEGSIKLPK 21 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 VSVGAPDLSLEAS(0.023)EGS(0.977)IKLPK;VSVGAPDLSLEAS(0.023)EGS(0.977)IKLPK 92.71600000000001 0.00019071 27543000.0 97197.0 74615.0 62571.0 87423.0 43087.0 29106.0 34710.0 29091.0 47699.0 59442.0 True False 95810.95295625321 74442.23355183177 57426.65391104479 93852.37905457897 40552.707372301265 27861.204229399886 36507.11396266566 30442.674061916805 42326.636327262386 69716.47049851359 1.3742943707727713 1.0677854604446584 0.8237171718592549 1.3462009534257757 0.581680441971971 0.3996358970868141 0.5236512075499292 0.4366640170426566 0.6071253467738993 1.0 16.089211912249077 -6.2815242278051935 20.603914278971224 0.5503103850186841 1.123392276467461 0.6237498477978305 0.21172025305069445 52.74769592884953 54110.34070900446 0.06342880082187076 0.07211949223213046 5.229687907264745e-07 6.2815242278051935 0.573081891448777 VSVHVIEGDHR ddPTM_PC-9_AZD4547_30min_R2 2 VSVHVIEGDHR 11 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 ; 104.07 0.0011477 10488800.0 18722.1 22374.0 76901.0 212994.0 111177.0 98432.0 45066.0 130934.0 60478.0 102722.0 False True 24675.338356128308 29605.957952583194 75881.24249377918 163891.52402449615 95741.99260471069 92277.03147957615 49076.78669558988 110701.15886399877 63674.743611715945 99125.73404614348 0.24892969109960716 0.298670756261956 0.7655049743032029 1.6533700920510097 0.9658641474487579 0.9309089346730162 0.49509632556914446 1.1167751737653402 0.6423634006288929 1.0 16.59697202385469 -5.33422427710449 4.053145310628038 0.9694354075939312 0.266173819810641 0.47267173738883483 0.2891840189086302 0.18878836762960777 5.939098941481095 0.07993528435730088 0.18508339499746296 4.632076496007982e-06 5.33422427710449 -0.7032615877832902 VSVHVIEGDHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSVHVIEGDHR 11 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 ; 104.82 0.0011083 5550500.0 10006.7 11691.900000000001 30488.0 26184.0 41585.0 38781.0 27251.0 21143.8 32268.0 16832.8 False True 11700.63666866602 12852.594562924785 31214.949546383865 24716.99536967335 33436.71777042029 36747.25608995129 24669.587999845306 20588.79765370792 32739.858454941543 19884.45339162851 0.588431396036869 0.6463639864667245 1.5698168278302067 1.243031170274933 1.6815507628938584 1.848039539544101 1.2406470278047155 1.0354218568751778 1.6465053280632418 1.0 14.279353283657592 -5.253416782202233 24.011810534061805 1.4229902855371115 0.617397437204354 0.5825953514715078 0.2674845689291873 238.65530165354346 714292.3087343473 0.06964086271002812 0.17698311815974094 5.5793450111027485e-06 5.253416782202233 -0.8055928483327575 VSVHVIEGDHR ddPTM_PC-9_Lapatinib_30min_R1 1 VSVHVIEGDHR 11 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 115.57 0.00056618 3674200.0 14663.0 10650.0 29602.0 12551.0 20339.0 29831.0 16527.0 18023.0 34366.0 12043.0 False True 14453.902931135131 10625.340579334048 27168.23782702445 13474.042408908625 19142.70000801251 28555.19766945742 17382.68719276794 18860.414376196302 30495.339189976716 14124.616503711179 1.0233129463966284 0.7522569251025178 1.9234672898826046 0.9539404064788861 1.3552721946810276 2.0216618031331803 1.2306661344186383 1.3352868285833328 2.1590206843466655 1.0 13.785924077115867 -5.242999836876208 24.919355749413164 1.4940990630681314 0.8877848471895765 0.27199501219573063 0.39891509824711857 1022.4372489764133 1381725.2026178623 0.09784203588400824 0.2578208013852815 5.71478851322948e-06 5.242999836876208 -0.6063142158785549 VSVPYPSSLLS(ph)PSREPPK ddPTM_PC-9_AZD4547_30min_R2 1 VSVPYPSSLLSPSREPPK 18 1 Q8WY91;Q9BQ29 Q8WY91 THAP4 THAP domain-containing protein 4 1 VSVPY(0.012)PS(0.049)S(0.049)LLS(0.826)PS(0.063)REPPK 48.354 0.039318 2803800.0 15224.0 15292.0 26224.0 52019.0 41826.0 24725.0 17877.0 35870.0 23095.0 27525.0 True False 20064.915321128366 20234.8399486414 25876.252625542784 40026.82323553846 36019.18186931307 23178.94184139838 19468.01836766211 30327.115710599446 24315.754550623024 26561.35812795794 0.7554175213656883 0.7618149588270722 0.9742066840439898 1.5069569501194688 1.356074553710415 0.8726565008361038 0.7329451406014692 1.1417757919041702 0.9154559956416068 1.0 14.697041295600858 -5.35682501831194 4.376956520003701 1.0801957681523988 0.7586791002885368 0.24847694119974506 0.21511898145670105 0.32559773922515456 10.65286552278493 0.06378886078585717 0.1421446538026331 4.39718746931294e-06 5.35682501831194 -0.321516667863862 VSVT(ph)PPEESQNSDTPPRPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VSVTPPEESQNSDTPPRPDR 20 1 Q05209-2;Q05209-3;Q05209;H3BM04 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 VS(0.077)VT(0.759)PPEES(0.102)QNS(0.051)DT(0.011)PPRPDR;VS(0.19)VT(0.801)PPEES(0.006)QNS(0.002)DT(0.001)PPRPDR 69.398 0.020617 6313400.0 19059.9 33339.0 35472.0 25702.0 33876.0 24255.6 30761.0 27389.0 22394.8 22556.0 True False 22286.36461981548 36648.67559022484 36317.787008309126 24262.000267008272 27238.240980900733 22983.593636456553 27847.095389645936 26670.067771044276 22722.281583200856 26645.22424680225 0.8364112237670551 1.3754313062170278 1.363012998949247 0.9105571806144588 1.0222560233911206 0.8625783526372409 1.0451064375255887 1.0009323818787155 0.8527712648516294 1.0 14.70158935445217 -5.776863303118045 24.996943736790072 0.9588948896886084 1.2099998133918024 0.3355625949099189 0.15103927467318068 242.41195316997243 392866.8624444694 0.04181426718342865 0.06227174760618716 1.6716166832341346e-06 5.776863303118045 0.25110492370319404 VSVT(ph)PPEESQNSDTPPRPDR ddPTM_PC-9_Lapatinib_30min_R1 2 VSVTPPEESQNSDTPPRPDR 20 1 Q05209-2;Q05209-3;Q05209;H3BM04 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 VS(0.233)VT(0.662)PPEES(0.039)QNS(0.055)DT(0.011)PPRPDR;VS(0.215)VT(0.568)PPEES(0.052)QNS(0.07)DT(0.094)PPRPDR 68.569 0.0036265 14366100.0 25337.5 44669.0 46352.0 47732.2 50562.0 40160.0 45819.0 49065.0 46514.0 42852.2 True False 24976.182603671565 44565.571674955194 42541.11748389426 51242.58521795143 47588.04256871674 38442.45041753243 48191.28362591121 51344.739020588735 41275.10350586558 50259.14567303266 0.49694801352488827 0.8867156629538085 0.8464353485164864 1.0195673748876803 0.9468533921827257 0.764884677261025 0.9588560048239937 1.0215999164533862 0.821245625112414 1.0 15.617098527414365 -4.697917359750083 2.910345263903083 0.9219612892230628 0.3630472349740405 0.7003897407568851 0.08284702083743678 0.34161928423606397 3.252259411167524 0.021132273173801966 0.49921661904131703 2.004853487037473e-05 4.697917359750083 -0.5589140542490223 down VSVTPPEES(ph)QNSDTPPRPDR ddPTM_PC-9_AZD4547_30min_R2 1 VSVTPPEESQNSDTPPRPDR 20 1 Q05209-2;Q05209-3;Q05209;H3BM04 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 VS(0.004)VT(0.092)PPEES(0.696)QNS(0.181)DT(0.027)PPRPDR 56.799 0.009504299999999999 8674700.0 6206.5 8056.1 11923.0 12471.0 15050.0 12205.0 12004.0 13245.0 10208.0 9999.3 True False 8180.037896780291 10660.076779378103 11764.893229650188 9596.003625029309 12960.567281909865 11441.819420597263 13072.332745170666 11198.289589821297 10747.574039954963 9649.227550550044 0.8477401796078482 1.104759601069874 1.21925751755948 0.9944841257767104 1.3431714833143367 1.1857756862563609 1.3547543237723203 1.1605374141252323 1.113827400551074 1.0 13.236197739623584 -4.229079414565447 1.3300976212907352 1.1888688302926447 1.1760595223198656e-14 0.4070216674988901 0.11518418013418034 4.6675258709351155 2.629585365117231 0.032461440201671084 10.778740055952111 5.90093166580548e-05 4.229079414565447 -1.188868830292633 VSVTPPEES(ph)QNSDTPPRPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSVTPPEESQNSDTPPRPDR 20 1 Q05209-2;Q05209-3;Q05209;H3BM04 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 VS(0.023)VT(0.138)PPEES(0.795)QNS(0.032)DT(0.012)PPRPDR 49.515 0.026248 5140700.0 13203.0 20626.0 19518.0 20979.0 20974.0 12530.0 19100.0 12605.0 17280.0 11822.0 True False 15438.0071288634 22673.61296751483 19983.383142427196 19803.61464483569 16864.29526311879 11872.904742195657 17290.709727974936 12274.132106101462 17532.687309451787 13965.235017099492 1.1054598873531736 1.6235754672049925 1.4309378336962382 1.4180652613856832 1.2075912251007301 0.8501757920764013 1.2381252235858276 0.8789062333052478 1.2554523635287331 1.0 13.769552232089689 -6.44535764730423 3.8250530275364514 1.0467162393915932 1.411329543363972 0.4798505329917562 0.1705630714469552 0.18933009102454101 5.251207907132883 0.05221150013416378 0.05829811044304833 3.586264793121646e-07 6.44535764730423 0.3646133039723789 VSVTPPEESQNS(ph)DTPPRPDR ddPTM_PC-9_AZD4547_30min_R2 1 VSVTPPEESQNSDTPPRPDR 20 1 Q05209-2;Q05209-3;Q05209;H3BM04 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 VSVTPPEES(0.025)QNS(0.868)DT(0.107)PPRPDR 63.373999999999995 0.0039291 4195500.0 8424.0 7758.0 8964.8 10009.0 10140.0 11496.0 9256.8 12392.0 7473.4 9717.9 True False 11102.656769914962 10265.621784041326 8845.920894503737 7701.579687508491 8732.2360291406 10777.153302678087 10080.637267202252 10477.101139831295 7868.428666751516 9377.679278898557 1.1839450294379241 1.0946868066964923 0.9432953112833182 0.8212671236089735 0.9311723902511447 1.1492345794901084 1.0749607624015758 1.1172381597019032 0.8390592632504374 1.0 13.195015223706447 -5.017790415054051 3.756796966804479 0.9905751201001696 1.1741043874430712 0.2814581006034016 0.10306690719321598 0.31462430077015296 9.557420149956435 0.028970878650731616 0.11511208042289396 9.5986373768932e-06 5.017790415054051 0.18352926734290165 VSVTPPEESQNS(ph)DTPPRPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VSVTPPEESQNSDTPPRPDR 20 1 Q05209-2;Q05209-3;Q05209;H3BM04 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 VS(0.003)VT(0.03)PPEES(0.181)QNS(0.664)DT(0.121)PPRPDR 65.189 0.0030898 8672000.0 9110.9 18359.0 16886.0 10485.0 15533.0 14695.0 7900.5 7728.3 11063.0 5695.7 True False 10653.195421522507 20181.560189595883 17288.62628051162 9897.559442828648 12489.420154573478 13924.368330930964 7152.107445333303 7525.440313810712 11224.775445860238 6728.285322863608 1.583344776613669 2.999510160637252 2.569544163319378 1.4710374141232425 1.8562560229324354 2.0695270284709997 1.0629911042906417 1.118478178717877 1.6682965877973335 1.0 12.716023171163629 -6.608074780108983 0.7064183966123797 1.1829396475846323 2.4104474104369453 0.44948540492597 0.46281515689423475 0.6629349237905479 0.7363536668167561 0.3292123181279211 0.39468032658885327 2.465614752482804e-07 6.608074780108983 1.227507762852313 VSVTPPEESQNS(ph)DTPPRPDR ddPTM_PC-9_Lapatinib_30min_R1 1 VSVTPPEESQNSDTPPRPDR 20 1 Q05209-2;Q05209-3;Q05209;H3BM04 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 VS(0.002)VT(0.003)PPEES(0.106)QNS(0.523)DT(0.365)PPRPDR 44.538999999999994 0.041773000000000005 2340800.0 5063.2 5859.1 7453.7 6404.5 6393.5 7459.6 8275.3 6995.7 11178.0 4862.3 True False 4990.997839522839 5845.533613932032 6840.885558114051 6875.5082947856945 6017.446900104627 7140.570297176922 8703.75454264612 7320.745761058447 9919.015930441707 5702.7420763925 0.8751926306090448 1.0250391014755238 1.1995782847050185 1.2056495283642699 1.0551848250361704 1.252129274219952 1.5262402588180932 1.283723805669549 1.7393414952963084 1.0 12.477440068636739 -6.975047293343468 3.861273557259189 1.4107975394775873 1.0852997775634443 0.3624252003694546 0.19583786751689233 0.23383399126539614 7.676126492451027 0.07131343378065656 0.05973561669400087 1.0591383819601887e-07 6.975047293343468 -0.32549776191414304 VSVTPPEESQNSDT(ph)PPRPDR ddPTM_PC-9_AZD4547_30min_R2 2 VSVTPPEESQNSDTPPRPDR 20 1 Q05209-2;Q05209-3;Q05209;H3BM04 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 VSVT(0.001)PPEES(0.014)QNS(0.12)DT(0.865)PPRPDR;VSVTPPEES(0.002)QNS(0.084)DT(0.913)PPRPDR 97.50200000000001 0.00031979 12675100.0 16731.3 19638.5 30302.0 27702.0 23138.1 28434.0 19646.6 29472.0 24989.0 21328.8 True False 22051.505367340724 25986.261073201273 29900.17568102492 21315.731891633564 19925.77420767831 26656.017485068605 21395.109339492672 24917.779599185607 26309.867523945395 20582.085203981467 1.0713931629762667 1.262566975875428 1.4527282043920862 1.0356449154874832 0.9681125119345926 1.2951077221229352 1.0395015435731425 1.21065379684491 1.2782897001541869 1.0 14.329101530928543 -11.217930359364022 2.6893160402060943 0.9728649191149688 1.1795973902236345 0.125157362608178 0.14223743403437894 46652054.36725341 39939257.49984914 8610585.675058378 0.03709485809574194 6.054379510590373e-12 11.217930359364022 0.20673247110866577 VSVTPPEESQNSDT(ph)PPRPDR ddPTM_PC-9_Lapatinib_30min_R1 1 VSVTPPEESQNSDTPPRPDR 20 1 Q05209-2;Q05209-3;Q05209;H3BM04 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 VS(0.015)VT(0.014)PPEES(0.011)QNS(0.113)DT(0.847)PPRPDR 56.121 0.015399000000000001 10132000.0 6734.4 8259.7 12766.0 7128.9 10607.0 8795.5 8697.8 12690.0 10744.0 8849.7 True False 6638.366221062293 8240.57517212445 11716.428758185062 7653.183087313257 9983.117114164359 8419.336968311914 9148.12952533775 13279.623727122615 9533.897580664314 10379.35885351597 0.6395738228872943 0.7939387478960692 1.1288200864368576 0.7373464194968814 0.9618240639962664 0.8111615647107041 0.8813771307501189 1.27942620681471 0.9185439789891011 1.0 13.341429708850159 -7.55868128609835 24.450802075076876 1.0754718497556923 0.8555192192938935 0.3033862316739656 0.14975673651018004 168.23366550472494 114890.45075916937 0.06845282693957287 0.03952144033835955 2.7626044936640648e-08 7.55868128609835 -0.2199526304617988 VSVTPPEESQNSDT(ph)PPRPDRLPLDEK ddPTM_PC-9_AZD4547_30min_R2 2 VSVTPPEESQNSDTPPRPDRLPLDEK 26 2 Q05209-2;Q05209-3;Q05209;H3BM04 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 VS(0.002)VT(0.009)PPEES(0.171)QNS(0.188)DT(0.631)PPRPDRLPLDEK;VSVT(0.001)PPEES(0.009)QNS(0.076)DT(0.914)PPRPDRLPLDEK 63.883 0.00030691 37850000.0 72066.0 50666.0 79204.0 107293.0 95601.0 96586.0 68840.0 83901.0 66163.0 81532.0 True False 94981.48893408019 67042.79367236889 78153.7032090258 82558.25651032549 82328.45134337968 90546.46215139756 74966.62663924921 70936.0283031783 69660.24110555841 78677.58949640935 1.207224185972486 0.8521205860714449 0.9933413531002058 1.0493236643211248 1.0464028177571068 1.1508545537675614 0.9528332924163939 0.9016039860552114 0.885388603685393 1.0 16.263665136926328 -7.504409932717113 23.894494237555513 0.9215414723866961 1.0392782507613736 0.2671673086288614 0.09263111906145498 585.354657676453 757322.0145595584 0.039262523803161635 0.02588664516690519 3.1303295957398664e-08 7.504409932717113 0.11773677837467744 VSVTPPEESQNSDT(ph)PPRPDRLPLDEK ddPTM_PC-9_Lapatinib_30min_R1 1 VSVTPPEESQNSDTPPRPDRLPLDEK 26 2 Q05209-2;Q05209-3;Q05209;H3BM04 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 VSVTPPEES(0.003)QNS(0.007)DT(0.989)PPRPDRLPLDEK 74.876 3.8892e-05 16306000.0 81445.0 54467.0 47875.0 45057.0 57321.0 46581.0 42011.0 44939.0 44449.0 38337.0 True False 80283.5793648164 54340.88500794248 43938.90230284427 48370.64208574582 53949.49147742199 44588.83921561449 44186.12401859826 47027.02999788524 39442.68555127957 44963.49936915851 1.7855278279315763 1.2085555121453944 0.9772126929467363 1.0757757462028044 1.199850817537284 0.9916674600776066 0.9827109686419676 1.0458934615338715 0.8772156550238215 1.0 15.456466699940822 -4.7623944867377395 2.5970438828054423 1.0270926348750375 1.9661623201257712 0.8946714379938585 0.07905379213887069 0.160702420396095 1.3501821216992334 0.02131373165893961 0.34246156937788197 1.7282458124685318e-05 4.7623944867377395 0.9390696852507336 VT(ph)GMNLCTVIMVRETTMK ddPTM_PC-9_AZD4547_30min_R2 1 VTGMNLCTVIMVRETTMK 18 1 F5H5G4 F5H5G4 WBP11 1 VT(0.999)GMNLCT(0.001)VIMVRETTMK 49.973 0.03982 0.0 4526.4 4829.0 8686.7 15400.0 11003.0 8155.1 7796.9 10942.0 8093.5 9116.7 True False 5965.701045031229 6389.879813758123 8571.508682211048 11849.767927628205 9475.423375604929 7645.160307817508 8490.808995403295 9251.165322146062 8521.305886792274 8797.52710790751 0.6781111296228981 0.726326811543972 0.9743088685122312 1.346943042321204 1.0770553201351438 0.8690124183812725 0.9651358718487464 1.0515642871768827 0.9686024018196023 1.0 13.10288233903441 -5.2849452098676375 4.114534041851675 1.0410117420236686 0.6937089860874732 0.559703256222126 0.11790525864423204 0.15589560349379517 6.231070421981632 0.03401860231723622 0.08397655044573674 5.188654943217976e-06 5.2849452098676375 -0.3473027559361954 VT(ph)KSPGETSKPR ddPTM_PC-9_AZD4547_30min_R2 1 VTKSPGETSKPR 12 2 Q9UNZ2-4;Q9UNZ2;Q9UNZ2-5;F2Z2K0;Q9UNZ2-6 Q9UNZ2-4 NSFL1C NSFL1 cofactor p47 1 VT(0.985)KS(0.015)PGETSKPR 55.776 0.03744 32273000.0 96439.0 93911.0 98763.0 120780.0 107160.0 108950.0 87667.0 120660.0 96742.0 95789.0 True False 127104.59594418693 124265.89422030238 97453.33808940215 92936.03703239844 92282.6837162431 102137.33927685942 95469.19316651736 102014.76949096538 101855.58461729255 92435.45626590222 1.3750632179339772 1.3443531220621219 1.0542852496888788 1.005415462710069 0.9983472516301575 1.1049584586140682 1.0328200565364032 1.103632454601696 1.1019103354051951 1.0 16.496158724342436 -5.250317005935489 5.405935071410476 1.0510734322894326 1.3647588026233783 0.9042272906668679 0.04033037192200193 0.046070613051721374 4.7705518582155975 0.010999428800967352 0.02764425079243587 5.619310033922446e-06 5.250317005935489 0.3136853703339457 VT(ph)NDISPESSPGVGR ddPTM_PC-9_AZD4547_30min_R2 1 VTNDISPESSPGVGR 15 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154;E9PGW9;E7EV93;E5RGQ4;Q15154-3 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 VT(0.842)NDIS(0.066)PES(0.091)S(0.001)PGVGR 100.4 0.0045861999999999995 74633000.0 10103.0 7103.2 12712.0 18499.0 16009.0 13531.0 10825.0 15934.0 11135.0 13828.0 True False 13315.54384454545 9399.17048935323 12543.430574126756 14234.341356700932 13786.426685454824 12684.904430979239 11788.404029196305 13471.766426894115 11723.573367446961 13343.885928915635 0.9978760246811785 0.704380308661484 0.9400133245253299 1.0667313429183112 1.0331643090248712 0.950615472775557 0.8834311153433448 1.0095834525759373 0.8785726609100033 1.0 13.703891240524165 -5.505017512913988 24.57695772999898 0.9749936229483046 0.843895308012981 0.23955945300111237 0.0866434638422648 729.1202067498276 1003263.2368085368 0.022094280971692085 0.0445052459390889 3.1259533105942453e-06 5.505017512913988 -0.13109831493532365 VT(ph)NDISPESSPGVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTNDISPESSPGVGR 15 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154;E9PGW9;E7EV93;E5RGQ4;Q15154-3 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 VT(0.997)NDISPES(0.003)SPGVGR 200.0 1.1673e-09 32555000.0 30287.0 36759.0 48859.0 39717.0 45939.0 34996.0 43352.0 34609.0 38112.0 31990.0 True False 35413.990904482795 40408.19058823221 50023.98385878932 37491.78525425135 36937.58272587081 33160.74815306297 39245.3847187 33700.55042126663 38669.31589917974 37789.53376729933 0.9371375450820678 1.06929582241099 1.3237523428266509 0.9921208736026897 0.9774553704029622 0.8775114389412811 1.038525242474954 0.8917958773661546 1.023281105750019 1.0 15.205699098841833 -5.974568223247241 24.998100116937767 0.9637779129451571 1.1146438888130403 0.28777032270656855 0.1002703936241727 268.45381074784564 263874.1139130083 0.028304060072043846 0.041980126917616094 1.0603073617835025e-06 5.974568223247241 0.1508659758678832 VT(ph)NDISPESSPGVGR ddPTM_PC-9_Lapatinib_30min_R1 4 VTNDISPESSPGVGR 15 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154;E9PGW9;E7EV93;E5RGQ4;Q15154-3 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 VT(0.925)NDIS(0.013)PES(0.061)SPGVGR;VT(0.88)NDIS(0.002)PES(0.117)S(0.001)PGVGR;VT(0.959)NDIS(0.001)PES(0.04)SPGVGR;VT(0.875)NDIS(0.02)PES(0.095)S(0.011)PGVGR 200.81 8.506900000000001e-10 218294000.0 229829.0 200847.0 232152.0 174834.0 249728.0 220317.0 199535.0 182567.0 228216.0 192492.0 True False 226551.59631452308 200381.9511115028 213065.35869263497 187691.87558912634 235039.4900241385 210894.5554940115 209865.94596774684 191049.72931360084 202511.91085898023 225763.98572053274 1.003488645859421 0.8875727032900204 0.9437526451024962 0.8313632264690133 1.0410849599151197 0.9341372797832879 0.9295811521840084 0.8462365186540258 0.8970071564455119 1.0 17.784455837578925 -7.5462283534726255 24.990592795383016 0.9005548632371602 0.937153782047874 0.016575390990913874 0.0646196388085031 728.1928388763753 779360.078885216 0.029373355785838832 0.016959784227978898 2.8429658735391183e-08 7.5462283534726255 0.036598918810713865 VT(ph)PGQLMS(ph)Y(ph)IQLFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTPGQLMSYIQLFK 14 0 A0A087WUD7;Q8WU76-2;Q8WU76 A0A087WUD7 SCFD2 Sec1 family domain-containing protein 2 3 VT(1)PGQLMS(1)Y(1)IQLFK 57.266999999999996 0.039231 0.0 7799.9 8997.7 9757.8 11214.0 12667.0 9328.3 12657.0 10154.0 10411.0 10067.0 True False 9120.26901495279 9890.932192272285 9990.462958662574 10585.715936278533 10184.992280820341 8839.10752646637 11458.037331255435 9887.468259052304 10563.241179323064 11892.067409671845 0.7669203932980783 0.8317252039984206 0.8400947130973466 0.8901493383454206 0.8564526192087394 0.7432776170842679 0.9635025548153711 0.8314339230040695 0.888259443495246 1.0 13.537711925785516 -14.522878745276158 0.12295899938660479 1.5131113265938114 0.7747377460291462 0.47313884694498964 0.0544720933247238 138.87017375703056 1.0942530963575452 17.569853311115605 0.4836253608708302 3.000000000028874e-15 14.522878745276158 -0.7383735805646652 VT(ph)PTKESYTEEIVSEAESHVSGISR ddPTM_PC-9_AZD4547_30min_R2 2 VTPTKESYTEEIVSEAESHVSGISR 25 1 Q5QJE6;J3KP30;E9PRB3 Q5QJE6 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 VT(0.553)PT(0.178)KES(0.178)Y(0.041)T(0.049)EEIVSEAESHVSGISR;VT(0.639)PT(0.154)KES(0.154)Y(0.023)T(0.03)EEIVSEAESHVSGISR 121.48 2.0384000000000003e-09 4621400.0 5283.9 4538.0 18253.5 42849.0 29039.0 22091.6 10218.900000000001 33579.0 14278.7 23554.0 True False 6964.0702880524295 6004.819754573279 18011.446663374973 32970.82506045073 25007.43609962661 20710.208759694095 11128.362303367594 28390.137118656792 15033.442931456206 22729.381629279633 0.30639066216748384 0.26418755479198625 0.7924301222595915 1.450581700734798 1.1002250966393394 0.9111646369215575 0.4896025103046452 1.2490501317503977 0.6614101156227832 1.0 14.472270814584796 -5.35023729541007 4.1188912527794335 0.9806039674543842 0.2823610641225386 0.5281284667405026 0.2578215121568286 0.16865860429229812 5.134846799721438 0.0705105428524173 0.1603164742784083 4.4643959408481325e-06 5.35023729541007 -0.6982429033318456 VT(ph)QHESDNENEIQIQNK ddPTM_PC-9_Lapatinib_30min_R1 1 VTQHESDNENEIQIQNK 17 0 Q5VZL5-2;Q5VZL5-4;Q5VZL5 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 VT(0.731)QHES(0.269)DNENEIQIQNK 121.82 0.00013985 16185000.0 68881.0 67515.0 77163.0 65559.0 68277.0 74743.0 66196.0 65056.0 68253.0 56422.0 True False 67898.74430877174 67358.67316560935 70818.95599779378 70380.42755841302 64261.08109774675 71546.416124443 69623.30498048443 68078.73925860423 60565.62840404708 66174.46752241063 1.0260565267983028 1.0178952047146834 1.0701855058192986 1.0635586532612145 0.9710857299453767 1.0811785693660942 1.0521173435495468 1.0287765328152991 0.9152416433654859 1.0 16.01398706056792 -8.133409121440545 6.355059625897579 0.9585754917436312 1.040345639228054 0.46277506602238594 0.03515688276753375 0.19616261573003232 9.092191324923041 0.023622692890159037 0.008746902598250832 7.355138897854994e-09 8.133409121440545 0.08177014748442268 VT(ph)RSPPETAAPVEDMAR ddPTM_PC-9_AZD4547_30min_R2 2 VTRSPPETAAPVEDMAR 17 1 Q9Y3L3;A0A2R8Y5V0;Q6ZT62-2;Q6ZT62;A0A3B3IU28 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 VT(0.97)RS(0.03)PPETAAPVEDMAR;VT(0.5)RS(0.5)PPETAAPVEDMAR 133.87 1.7976e-05 35763000.0 25056.5 30071.0 49056.0 60308.0 61831.0 43916.0 37051.0 45105.0 37578.0 43563.0 True False 33023.945792423336 39790.86267954454 48405.485387379005 46404.92234931184 53246.832930748766 41169.92557762796 40348.4672227023 38135.0586597878 39564.296362992536 42037.872629545236 0.7855760467101588 0.9465479623623617 1.1514732397128598 1.1038836993073082 1.266639570464981 0.9793532118153081 0.9598123001672643 0.907159574792221 0.9411583861925922 1.0 15.359402041607328 -6.983525736596632 24.994699791754737 0.9479082059795955 1.0605129501693171 0.13026540831308497 0.12074045409612781 486.84851607531357 738642.4196055845 0.04618209760314445 0.04071825765852129 1.0386620487548163e-07 6.983525736596632 0.11260474418972166 VT(ph)RSPPTQVAISSDSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VTRSPPTQVAISSDSAR 17 1 Q6ZUT6;Q6ZUT6-4;H0YM82;Q6ZUT6-3 Q6ZUT6 C15orf52 Uncharacterized protein C15orf52 1 VT(0.814)RS(0.039)PPT(0.127)QVAIS(0.01)S(0.01)DSAR;VT(0.556)RS(0.443)PPT(0.001)QVAISSDSAR;VT(0.885)RS(0.115)PPTQVAISSDSAR 161.75 0.00031465 87132000.0 34647.5 22698.7 30800.899999999998 33961.1 41161.1 41481.7 34566.9 44878.0 36729.1 28888.6 True False 40512.63743068202 24952.07692551775 31535.310269063724 32058.369670371765 33095.87793242867 39306.32662764066 31292.472989316073 43700.00005217148 37266.1936028695 34125.87449796824 1.1871530920942124 0.7311776560334983 0.9240879752676009 0.9394153305076602 0.9698177239208657 1.1518042308331424 0.9169720468607813 1.2805532662547083 1.0920216448984545 1.0 15.058578396064483 -6.623268013909201 5.091657584694455 1.094592888900295 0.9314683454094856 0.202734800913132 0.13571657019617897 0.30208408025575445 12.606631393846069 0.04395657541764346 0.04388558944666735 2.3808497344079043e-07 6.623268013909201 -0.1631245434908093 VT(ph)RSPPTQVAISSDSAR ddPTM_PC-9_Lapatinib_30min_R1 1 VTRSPPTQVAISSDSAR 17 1 Q6ZUT6;Q6ZUT6-4;H0YM82;Q6ZUT6-3 Q6ZUT6 C15orf52 Uncharacterized protein C15orf52 1 VT(0.933)RS(0.063)PPT(0.004)QVAISSDSAR 143.76 0.0011947000000000001 25632000.0 19218.0 15415.0 23233.0 16401.0 17430.0 16453.0 14690.0 13192.0 19953.0 13479.0 True False 18943.947795850425 15379.307514594782 21322.872421973498 17607.184252132123 16404.80166869847 15749.343543816267 15450.57632127797 13804.948479763727 17705.683025595208 15808.82719036146 1.1983145598175953 0.9728303895921796 1.3487953385292184 1.1137565133779885 1.0376988419925528 0.9962373143922112 0.977338554924434 0.8732430504509857 1.1199871320239523 1.0 13.948442721982587 -6.3232951605532435 2.7174652907979167 0.9867404293412748 1.1618590088173861 0.3730986461403487 0.10211961190872436 0.29807227297851985 4.33413089677626 0.03308729812358002 0.03989191394272982 4.7501228252852615e-07 6.3232951605532435 0.1751185794761113 VT(ph)RY(ph)LCFT(ph)RSFS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 VTRYLCFTRSFSK 13 2 F8W922;Q9H7P6-2;Q9H7P6 F8W922 MVB12B Multivesicular body subunit 12B 4 VT(1)RY(1)LCFT(0.797)RS(0.218)FS(0.985)K 56.043 0.037837 0.0 8844.9 8381.4 5995.6 3627.4 4141.5 3804.3 4044.3 1820.7 5285.3 1507.9 True False 8718.770104043988 8361.993383251685 5502.664911685289 3894.171096651671 3897.905112502282 3641.598957256441 4253.694065088118 1905.2963687921313 4690.013857323628 1768.5385058495474 4.929929472955286 4.728194130686942 3.111419340593882 2.201914792226161 2.204026149054559 2.059100746300764 2.405202969015811 1.0773281794488778 2.6519150370835156 1.0 10.788341915402034 -5.408875144502617 1.551380025541944 1.9286347346521344 5.14359884659452 0.8438745689083544 0.495608525190717 0.160279921845123 0.6903934041123894 0.141498571772816 0.5388196180548227 3.900541073730599e-06 5.408875144502617 3.2149641119423853 VT(ph)SLRSPGASVSSSLTSLCSSSSDPAPSDR ddPTM_PC-9_AZD4547_30min_R2 1 VTSLRSPGASVSSSLTSLCSSSSDPAPSDR 30 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 VT(0.393)S(0.393)LRS(0.208)PGAS(0.003)VS(0.002)SSLTSLCSSSSDPAPSDR 54.702 0.0015921 4847400.0 5096.6 5404.1 9800.1 16909.0 14626.0 11933.0 7641.9 10019.0 8358.8 14252.0 True False 6717.212784134449 7150.869642064674 9670.14427072841 13010.891291445807 12595.432363137117 11186.827623595836 8322.014295678076 8470.793763716081 8800.629103171588 13753.041817971181 0.48841651709057027 0.519948222124984 0.7031276715884318 0.9460373540378826 0.9158288420732198 0.8134075189808514 0.6051035404257734 0.6159214721973174 0.6399041913529089 1.0 13.747463120395064 -5.318638154912828 3.653596438980225 0.775920681110414 0.49781373420789304 0.41886266317599374 0.1321976627372691 0.24642786438329542 6.612271100264361 0.03898418017187023 0.09550307332784556 4.801333190801533e-06 5.318638154912828 -0.27810694690252097 VT(ph)VSEEEILPATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTVSEEEILPATR 13 0 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 VT(0.69)VS(0.309)EEEILPATR 111.72 0.0013081 1476600.0 4596.4 4562.3 3839.2 6448.2 6680.5 5462.6 6529.8 5392.8 4939.7 3895.2 True False 5374.479736961883 5015.214992809702 3930.741088247081 6086.928259346466 5371.503981370513 5176.131639642293 5911.250072341929 5251.24471414391 5011.933767505726 4601.368925613763 1.168017566912437 1.0899397709434344 0.8542547124109964 1.3228516030225828 1.1673708559793483 1.1249112434408557 1.284672054752368 1.1412353147587404 1.08922667330727 1.0 12.167847417220562 -4.35559827660323 10.63409143221913 1.128717859784863 3.530792514717181 0.00840500628827101 0.1259509743287898 408307.0430916076 293653.1566663091 0.20694494676121108 23355104.514983397 4.4096256630468e-05 4.35559827660323 2.402074654932318 VTAEADSS(ph)SPTGILATSESK ddPTM_PC-9_AZD4547_30min_R2 2 VTAEADSSSPTGILATSESK 20 0 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 VTAEADSS(0.919)S(0.081)PTGILATSESK;VTAEADSS(0.5)S(0.5)PTGILATSESK 360.25 1.4120999999999994e-249 28437700.0 87732.0 96423.0 116904.0 133940.0 125189.0 114189.0 98085.0 134016.0 91985.0 121130.0 True False 115628.95106103718 127589.84909546483 115353.77657628337 103062.20235237166 107808.6682694361 107048.74377866277 106814.37498417712 113306.90658131275 96847.13930890057 116889.27556910276 0.9892177917783356 1.0915445277102098 0.9868636452288421 0.8817079398481105 0.9223144530971246 0.9158132194546587 0.9138081698609763 0.9693524579534915 0.8285374243049899 1.0 16.83478304508464 -5.548458482672427 5.28544513195791 0.9178490190875382 1.0408197084822255 0.5044914205573876 0.04900659013450233 0.12161544756579991 9.437913625439679 0.012328339613367165 0.022661461620178163 2.8284044856152567e-06 5.548458482672427 0.12297068939468725 VTAEADSS(ph)SPTGILATSESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VTAEADSSSPTGILATSESK 20 0 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 VTAEADSS(0.794)S(0.206)PTGILATSESK;VTAEADS(0.137)S(0.736)S(0.099)PT(0.025)GILAT(0.002)SESK;VTAEADSS(0.935)S(0.064)PTGILATSESK 386.36 0.0 19024700.0 125758.0 142198.0 130066.0 143564.5 177716.0 154622.0 151676.0 134846.0 122785.0 104486.4 True False 147046.34556628054 156314.47768615713 133167.26671805175 135521.04650738873 142893.82554498044 146513.35012352577 137308.15124085455 131306.43538114734 124580.49833860189 123428.9572061129 1.1913439835737183 1.26643278226137 1.078898094356229 1.097968009898061 1.1577009867009032 1.1870257469555094 1.112446822438635 1.063821961663987 1.0093295864970004 1.0 16.913321373922273 -5.342802144550668 0.13103616971676094 0.9215325777905867 1.427548224107583 0.5857084086161881 0.0516367491260614 21.30078434491149 0.5765225818150538 0.48302212661248445 2.051998619233465 4.541484700371497e-06 5.342802144550668 0.5060156463169962 VTAEADSSS(ph)PTGILATSESK ddPTM_PC-9_AZD4547_30min_R2 2 VTAEADSSSPTGILATSESK 20 0 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 VTAEADS(0.032)S(0.186)S(0.757)PT(0.022)GILAT(0.002)S(0.001)ESK;VTAEADS(0.008)S(0.039)S(0.927)PT(0.027)GILATSESK 171.52 1.32e-08 28169000.0 69576.0 70587.0 95251.0 116471.0 109659.0 103329.0 85310.0 116833.0 88932.0 96835.0 True False 91699.72072929767 93402.86734598153 93987.90950410215 89620.41040901211 94434.74070212338 96867.8212954438 92902.42473263147 98779.14440525397 93632.76396172357 93444.83612428002 0.9813246459904817 0.9995508710803167 1.0058117002752283 0.9590729046794894 1.0105934647531172 1.036631078967395 0.9941953839918222 1.0570851049904932 1.002011109925792 1.0 16.51182732063348 -6.508350055287395 24.40802106780188 1.0204596169734423 0.9882693288519643 0.3346560844190105 0.02094603452528536 541.0859146744924 909019.7906959642 0.0062742931675236905 0.006866471510458423 3.1020582217121565e-07 6.508350055287395 -0.03219028812147806 VTAEADSSS(ph)PTGILATSESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VTAEADSSSPTGILATSESK 20 0 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 VTAEADS(0.059)S(0.26)S(0.621)PT(0.057)GILAT(0.002)SESK;VTAEADS(0.024)S(0.187)S(0.784)PT(0.005)GILATSESK;VTAEADSS(0.006)S(0.985)PT(0.009)GILATSESK 185.2 1.6158e-11 19923400.0 70117.0 77445.0 72570.0 77603.0 87687.0 78728.0 84872.0 66516.0 66013.0 67113.0 True False 81986.42322612413 85133.2277838255 74300.34402325773 73255.15550232049 70505.3618163965 74599.36508727692 76832.3097399313 64770.02547952753 66978.3152406736 79280.05563378417 1.0341368023862318 1.073829062091968 0.9371883436418226 0.924004844808708 0.8893202868332947 0.9409600496734183 0.9691253257293402 0.816977548284245 0.8448318395494625 1.0 16.274670354467347 -5.366523870240126 3.704375371548616 0.9083241585070986 1.05452258221487 0.5324269143799316 0.052144592745755954 0.17530090898615663 4.321066053663524 0.01446671470220388 0.03359196817609863 4.300075983619792e-06 5.366523870240126 0.14619842370777147 VTAEADSSS(ph)PTGILATSESK ddPTM_PC-9_Lapatinib_30min_R1 4 VTAEADSSSPTGILATSESK 20 0 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 VTAEADSS(0.026)S(0.973)PTGILATSESK;VTAEADS(0.056)S(0.377)S(0.5)PT(0.043)GILAT(0.02)S(0.004)ES(0.001)K;VTAEADSS(0.05)S(0.934)PT(0.014)GILAT(0.001)SESK;VTAEADSS(0.003)S(0.992)PT(0.005)GILATSESK 289.81 4.1867999999999993e-107 48501700.0 132694.0 147559.0 166115.0 144304.0 162004.0 160739.0 142820.0 142357.0 163939.0 128267.0 True False 130801.75922690061 147217.33620149794 152457.66592244364 154916.5975440321 152475.24323211846 153864.56767091015 150214.5207763732 148971.42591977908 145474.46346579728 150437.78004496556 0.8694741386625369 0.9785928518587217 1.0134267195173603 1.0297718930559054 1.0135435605772958 1.0227787702325861 0.9985159361662633 0.9902527534988339 0.9670075124899825 1.0 17.198807396764217 -4.763889901915252 2.965022033107787 1.0055323037404387 0.8433384977613018 0.8519703658377198 0.01681016477690742 0.16085373748415313 1.9560178143791622 0.004754377290407373 0.06440501827837135 1.7223051415825273e-05 4.763889901915252 -0.1621938059791369 VTAGWPSEPGQGDLNPES(ph)PAALGQDLLEPR ddPTM_PC-9_AZD4547_30min_R2 2 VTAGWPSEPGQGDLNPESPAALGQDLLEPR 30 0 Q92766;Q92766-2;Q92766-5;Q92766-3;A0A087X055;Q92766-4 Q92766 RREB1 Ras-responsive element-binding protein 1 1 VTAGWPSEPGQGDLNPES(1)PAALGQDLLEPR;VTAGWPSEPGQGDLNPES(1)PAALGQDLLEPR 98.11200000000001 1.3913e-12 13689200.0 28971.3 27466.0 37929.6 54922.4 44671.0 43723.6 32464.8 46310.0 32242.7 38567.2 True False 38183.57075952484 36343.84737309601 37426.62872123963 42260.88922262129 38469.202727587755 40989.55638004313 35354.10430734892 39153.8535979331 33946.98329722336 37216.97406694207 1.0259719312710418 0.9765395571312281 1.0056333073699235 1.1355272770592995 1.0336467080422311 1.101367249962754 0.9499456953098225 1.0520429072902908 0.9121371134623415 1.0 15.183673141123817 -7.275352554516705 24.97200707878411 0.9828683397192843 1.0448820451140246 0.27281767333910256 0.054099487808542665 1249.8436176886823 2243266.649534183 0.02294852416288639 0.015565041063479355 5.3045365413881034e-08 7.275352554516705 0.06201370539474027 VTAGWPSEPGQGDLNPES(ph)PAALGQDLLEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VTAGWPSEPGQGDLNPESPAALGQDLLEPR 30 0 Q92766;Q92766-2;Q92766-5;Q92766-3;A0A087X055;Q92766-4 Q92766 RREB1 Ras-responsive element-binding protein 1 1 VTAGWPSEPGQGDLNPES(1)PAALGQDLLEPR;VTAGWPSEPGQGDLNPES(1)PAALGQDLLEPR 131.37 1.628e-15 10043900.0 55317.0 56083.0 60556.0 60692.0 77257.0 65507.0 67271.0 59581.0 59308.0 53929.0 True False 64681.07553944843 61650.54960036531 61999.88469990891 57291.624006118815 62119.04544401484 62071.697601517226 60898.60388013624 58017.06188128772 60175.26730028735 63705.90079827089 1.0153074476454778 0.9677368788110541 0.9732204383426866 0.8993142438647351 0.9750909203955699 0.9743476950129237 0.9559334868048699 0.9107015387005158 0.9445791762812752 1.0 15.959139388736318 -4.643626785203548 1.5663282292122216 0.950314089277105 1.0562441035658963 0.28460207057618514 0.02889192208418112 1.9153575447508786 3.4674838113528668 0.008107813750961578 0.3457322444876957 2.2718163186649274e-05 4.643626785203548 0.10593001428879123 VTAGWPSEPGQGDLNPES(ph)PAALGQDLLEPR ddPTM_PC-9_Lapatinib_30min_R1 1 VTAGWPSEPGQGDLNPESPAALGQDLLEPR 30 0 Q92766;Q92766-2;Q92766-5;Q92766-3;A0A087X055;Q92766-4 Q92766 RREB1 Ras-responsive element-binding protein 1 1 VTAGWPSEPGQGDLNPES(1)PAALGQDLLEPR 100.82 7.282100000000001e-13 3817000.0 25009.0 25000.0 26907.0 17052.0 18422.0 27425.0 22566.0 21555.0 23502.0 17107.0 True False 24652.367073911082 24942.11403599543 24694.810324023627 18306.060963804463 17338.454179045515 26252.09668079748 23734.357063713986 22556.523990396232 20854.957272968415 20063.922156355333 1.2286913237500945 1.2431325162460776 1.230806725204595 0.9123869610910517 0.8641607579978318 1.3084229731464552 1.1829370588041295 1.124233029545091 1.0394257468927888 1.0 14.2923160354706 -5.581613058188725 24.957573542677956 1.0737552624121702 1.2361768685951056 0.2961316521382764 0.12092557952871165 105.09257217079056 44655.5124203567 0.03592253241216476 0.06221966220401054 2.6205167609233955e-06 5.581613058188725 0.16242160618293533 VTAIHIDPATHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VTAIHIDPATHR 12 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 ; 88.803 0.0032963999999999997 3861500.0 25207.5 31723.6 29924.8 35389.0 37843.0 30377.1 33781.1 27964.1 32013.9 25575.3 False True 29474.631879180815 34872.909354031515 30638.320722435987 33406.26906268602 30427.93580824852 28784.071400171688 30581.10965401539 27230.072005413098 32482.042723151502 30211.89943603659 0.9755967823732272 1.1542772882540215 1.0141143487949904 1.105732167996005 1.0071507047304098 0.9527395475783361 1.0122206886978582 0.9013028811069461 1.0751407005018392 1.0 14.88282926936858 -6.455767197234957 6.113666901577429 0.983150951580918 1.0650911698797705 0.24609410434462586 0.061190764102750095 0.28162228375955384 19.941861914654208 0.01773855573130148 0.019960403642131544 3.5013280478392654e-07 6.455767197234957 0.08194021829885245 VTAIHIDPATHR ddPTM_PC-9_Lapatinib_30min_R1 1 VTAIHIDPATHR 12 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 94.538 0.0020517 1744000.0 21680.0 21645.0 23960.0 19440.0 21721.0 21526.0 18425.0 20245.0 23085.0 14124.0 False True 21370.83922437493 21594.88233236485 21990.101288274636 20869.682449938948 20443.413485129062 20605.38315955686 19378.956345782604 21185.656608006113 20484.924204173087 16565.31458095299 1.290095586168185 1.30362041884764 1.327478641037046 1.2598422051057923 1.2341095839275615 1.2438872234427225 1.1698513934691452 1.2789166486681547 1.2366154656505537 1.0 14.015877980497594 -14.522878745122894 0.1676317413930409 0.0007573969287898273 1.323047918396016 0.8408935406693893 0.035316447380270496 53.043119648697555 0.49588361548773513 17.621516139702457 0.14232409164719478 3.0000000010875846e-15 14.522878745122894 1.3222905214672263 VTAPDVDLHLK ddPTM_PC-9_Lapatinib_30min_R1 1 VTAPDVDLHLK 11 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 119.39 0.00081421 3390800.0 24606.0 31131.0 30263.0 30544.0 30372.0 26830.0 32668.0 30944.0 31234.0 28597.0 False True 24255.113927812254 31058.91808218292 27774.892958558255 32790.30765179706 28585.578673649467 25682.543443784747 34359.3891942484 32381.77120662588 27716.09801139883 33539.95334689272 0.7231707711978481 0.9260274682242619 0.8281136431912013 0.9776491729925109 0.852284389843904 0.765729849954132 1.024431633487397 0.9654685822520938 0.8263606608136969 1.0 15.033593061705933 -1.5228787452803376 0.13957758359523417 0.9937649814264677 0.36705236392693824 0.23018918474335337 0.08659677213688884 129.84331313155582 1.2125351618247249 0.38027636506194623 16.218125265056855 0.029999999999999995 1.5228787452803376 -0.6267126174995294 VTAQGPGLEPSGNIANK ddPTM_PC-9_Lapatinib_30min_R1 1 VTAQGPGLEPSGNIANK 17 0 Q60FE5;P21333-2;P21333;A0A087WWY3;F8WE98 Q60FE5 FLNA Filamin-A 0 242.26 7.052100000000001e-38 4762200.0 21211.0 14886.0 19239.0 17958.0 12818.0 14611.0 20609.0 14963.0 12062.0 15421.0 False True 20908.527250378982 14851.53238159312 17657.243684687637 19278.69122613187 12064.070441157612 13986.121589904547 21676.03317938853 15658.235605117085 10703.450541509026 18086.499302809112 1.1560295278993855 0.8211391343866333 0.9762665173102456 1.0659161235882497 0.6670207561550552 0.773290693557945 1.1984648226548689 0.8657416420371143 0.5917922734692288 1.0 14.14262557649648 -6.218072843734928 24.99864365840095 0.8563210606152759 0.9896756690181456 0.15375053533834648 0.17679635756163914 1122.2959922241678 646947.1948176081 0.05374088758412627 0.06937869328161701 6.052393501105237e-07 6.218072843734928 0.13335460840286972 VTDALNATR ddPTM_PC-9_Lapatinib_30min_R1 2 VTDALNATR 9 0 P10809 P10809 HSPD1 60 kDa heat shock protein, mitochondrial 0 ; 128.86 0.0060664 21233800.0 115006.0 104881.0 115168.0 96543.0 77290.0 81392.0 86213.0 73100.0 124757.0 69292.0 False True 113365.9933504826 104638.1544883696 105699.33160133628 103643.09427800693 72743.95415798655 77911.05389401896 90676.68729655113 76496.4928646702 110705.55291054885 81269.0298742138 1.39494704841374 1.287552646442636 1.3006102295663564 1.2753086192664433 0.8951005600851621 0.9586807424009831 1.1157594404276545 0.9412748372051394 1.3622108333506155 1.0 16.310418052154148 -6.123645132327575 6.140077383368038 1.0423892988346508 1.317885520499821 0.5292743209432811 0.12483440712066646 0.18880305975216627 8.680510076679074 0.03640341836130806 0.0473681396905892 7.522373058531757e-07 6.123645132327575 0.2754962216651702 VTDALPEPEPPGAMAAS(ph)EDEEEEEEALEAMQSR ddPTM_PC-9_Lapatinib_30min_R1 1 VTDALPEPEPPGAMAASEDEEEEEEALEAMQSR 33 0 Q9Y3E7-2;Q9Y3E7-4;Q9Y3E7;Q9Y3E7-3 Q9Y3E7-2 CHMP3 Charged multivesicular body protein 3 1 VTDALPEPEPPGAMAAS(0.999)EDEEEEEEALEAMQS(0.001)R 73.797 0.00010292 0.0 3669.5 3136.0 4409.2 3388.7 3844.8 3993.2 2842.1 3353.9 4177.1 3476.0 True False 3617.1722570961156 3128.738784675264 4046.6925960041995 3637.9163023718165 3618.6564231676343 3822.420144603851 2989.2500314978984 3509.7344380139116 3706.631011186977 4076.8219685211407 0.8872529350130631 0.7674455271369645 0.992609593269075 0.892341223252254 0.8876169847760841 0.9375980050437245 0.7332304561197808 0.8608996088409181 0.9091961924772375 1.0 11.993229241552394 -8.62142815057079 3.5097160490688677 0.9999073487782202 0.8700098101578851 0.237490816881198 0.0707378771902065 0.6536493710339474 18.414600284645058 0.0686754293618182 0.01809999290837026 2.390957461252669e-09 8.62142815057079 -0.12989753862033504 VTDKLTPIHDR ddPTM_PC-9_Lapatinib_30min_R1 1 VTDKLTPIHDR 11 1 P28072;I3L3X7;A0A087X2I4 P28072 PSMB6 Proteasome subunit beta type-6;Proteasome subunit beta type 0 80.737 0.007134899999999999 4552700.0 167680.0 67031.0 97829.0 79756.0 86645.0 83784.0 49629.0 48042.0 101860.0 56158.0 False True 165288.85245125374 66875.79383787242 89785.87725086068 85621.5222982166 81548.71145062425 80200.75363004336 52198.546783438025 50274.20670594367 90387.45416664814 65864.83547416875 2.5095159087746857 1.015348984878284 1.363183808241249 1.2999580380307203 1.2381221461124956 1.217656630471611 0.7925100914266999 0.7632935897283232 1.3723173149365386 1.0 16.007220810986524 -4.758798267749677 24.99179598843457 1.1206841920941586 2.5095177591029287 0.7989296262204221 0.20941501102260374 33.00699504824055 312270.0296691151 0.05584353487367685 0.3717603837361252 1.742616140504508e-05 4.758798267749677 1.3888335670087701 VTEGLTDVILYHQPDDK ddPTM_PC-9_AZD4547_30min_R2 1 VTEGLTDVILYHQPDDK 17 0 O60506-2;O60506;O60506-4;O60506-3;B7Z645;O60506-5 O60506-2 SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0 88.95100000000001 0.0022144 4192900.0 56909.0 49954.0 57104.0 70566.0 68745.0 61647.0 52981.0 59250.0 52600.0 63239.0 False True 75004.87821926516 66100.65359628778 56346.76364890925 54298.09893383199 59200.94337507594 57792.203344658694 57696.20636220319 50094.27392955162 55380.32861497171 61025.02185845351 1.229084004152226 1.0831729605866773 0.9233386885072258 0.8897677916408698 0.9701093350264014 0.9470247053529406 0.9454516295959475 0.820880884659811 0.9075019873557019 1.0 15.897113286312566 -4.985808875765226 2.1634245596642474 0.9196867905113909 1.2514989116328539 0.8139667985515721 0.04659276596015086 0.17617407918043856 1.2945976207262597 0.01307696132015485 0.09699100458348148 1.0332160032308964e-05 4.985808875765226 0.33181212112146297 VTEGLTDVILYHQPDDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTEGLTDVILYHQPDDK 17 0 O60506-2;O60506;O60506-4;O60506-3;B7Z645;O60506-5 O60506-2 SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0 99.238 0.0010720999999999999 3391000.0 17514.0 20829.0 15262.0 17780.0 19787.0 12520.0 16225.0 16717.0 15534.0 13359.0 False True 20478.774282732247 22896.765465934564 15625.903961457321 16783.844243537755 15909.87939216799 11863.429159799636 14688.05054117242 16278.196463125607 15761.155362559257 15780.880950214194 1.2976952520799727 1.4509180785388147 0.9901794463030424 1.0635555959447212 1.0081743498579554 0.7517596259186413 0.9307497209763222 1.0315137991649739 0.9987500325414552 1.0 13.945890124002858 -5.270609550437966 23.461960963163428 0.96820712983665 1.3743066667324577 0.7706179496607459 0.08781462536495035 117.0738420737331 299536.22517141025 0.024661612421271357 0.05264416111220673 5.362785785319467e-06 5.270609550437966 0.4060995368958077 VTEGLTDVILYHQPDDK ddPTM_PC-9_Lapatinib_30min_R1 1 VTEGLTDVILYHQPDDK 17 0 O60506-2;O60506;O60506-4;O60506-3;B7Z645;O60506-5 O60506-2 SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0 131.72 2.1408000000000002e-05 4783800.0 61199.0 48473.0 47743.0 49656.0 50795.0 45709.0 44402.0 41126.0 42793.0 43022.0 False True 60326.29103747787 48360.76374667226 43817.754833309526 53307.86788756011 47807.33796681232 43754.132622883255 46700.9182993454 43036.86409784438 37973.20170973269 50458.295376788374 1.1955673608670683 0.958430390593793 0.868395464137427 1.0564738164357923 0.9474624065244278 0.8671345771028733 0.9255349977761749 0.8529195006782181 0.752566083062746 1.0 15.622803848388559 -2.0690422096968466 1.1545759608340032 0.9034392483963717 199.97298420808372 0.5314827354781012 0.07987556728252167 870.4349098006526 2.296959915605989 0.02501880735713424 457526.96568571083 0.008530172040363165 2.0690422096968466 199.06954495968733 VTEGSFVYK ddPTM_PC-9_Lapatinib_30min_R1 2 VTEGSFVYK 9 0 P50395;Q5SX87;V9GYJ7;V9GYF8;Q5SX90;Q5SX86 P50395 GDI2 Rab GDP dissociation inhibitor beta 0 ; 104.2 0.0060661000000000005 2785600.0 46133.0 38725.0 39093.0 41388.0 45707.0 41809.0 40542.0 36964.0 37341.0 39208.0 False True 45475.134960243944 38635.334641756934 35878.92444334393 44431.81158632062 43018.60412341947 40020.926531539175 42641.066386470484 38681.48238371637 33135.26336183787 45985.050558623945 0.9889112745949917 0.8401716247436275 0.7802301836681415 0.966222958256332 0.9354910693982449 0.8703029798894878 0.9272810591370256 0.8411751626629912 0.7205659874092222 1.0 15.48887730614775 -7.846631145777109 7.8047926450215055 0.8346377005854084 0.8967788864798824 0.04504075039330846 0.08579347323123743 0.6212823023118877 49.226869330231075 0.04602944247968781 0.022028452991731604 1.423537310035682e-08 7.846631145777109 0.06214118589447393 VTELEDEVR ddPTM_PC-9_Lapatinib_30min_R1 2 VTELEDEVR 9 0 U3KQC1;K7EIR0;A0A0A0MQU0;Q9BV38 U3KQC1 WDR18 WD repeat-containing protein 18 0 ; 117.89 0.0084355 1807070.0 12907.3 11820.8 12842.099999999999 14204.6 11191.5 13560.9 15269.599999999999 11892.6 13678.5 10445.1 False True 12723.239535091065 11793.429663867784 11786.272109939562 15249.25366915651 10533.237973335568 12980.93191900189 16060.18517327338 12445.173612070796 12137.883289009385 12250.521617779097 1.03858757464057 0.9626879598948719 0.9621036946569056 1.2447840300143116 0.8598195490752617 1.0596227919113872 1.310979701465556 1.0158892821354808 0.9908054259007029 1.0 13.580555558929273 -6.996161010767411 24.99962588534273 1.0956796495664467 1.014648330965841 0.05355171005944792 0.1248367378802828 307.6564893864327 2003454.9991852136 0.04441746507886645 0.03899234109278898 1.0088787840114324e-07 6.996161010767411 -0.08103131860060575 VTENGGS(ph)PQGIK ddPTM_PC-9_AZD4547_30min_R2 1 VTENGGSPQGIK 12 0 Q92766;Q92766-2;Q92766-5;Q92766-3;C9JU34;Q92766-6;C9JE09;C9JPJ6 Q92766 RREB1 Ras-responsive element-binding protein 1 1 VT(0.05)ENGGS(0.95)PQGIK 109.6 0.0022296 0.0 12654.0 9565.7 13068.0 16731.0 16789.0 17935.0 12129.0 15667.0 14105.0 17043.0 True False 16677.708780449193 12657.625457541124 12894.709781520483 12873.92644137322 14458.137149234863 16813.521614781792 13208.45750301357 13246.02514184448 14850.561504071775 16446.32975748546 1.0140687330471665 0.7696322306671538 0.7840478679233296 0.7827841610383448 0.8791102551409271 1.022326674869766 0.8031249341210498 0.8054091908144808 0.9029711627491004 1.0 14.005478040624611 -6.502341816857272 24.09623620695634 0.895081480570284 0.8291983281953018 0.10134471091749697 0.0925616733869582 1221.8070634758535 1433562.6171943948 0.029427056526408472 0.0329544061405834 3.1452718144660605e-07 6.502341816857272 -0.06588315237498221 VTENGGSPQGIKS(ph)PSKPPGPNR ddPTM_PC-9_AZD4547_30min_R2 1 VTENGGSPQGIKSPSKPPGPNR 22 2 Q92766;Q92766-2;Q92766-5;Q92766-3;C9JU34;Q92766-6;C9JE09;C9JPJ6 Q92766 RREB1 Ras-responsive element-binding protein 1 1 VTENGGSPQGIKS(0.809)PS(0.19)KPPGPNR 50.88399999999999 0.010762 19985000.0 37770.0 30668.0 39188.0 42917.0 34468.0 44984.0 33220.0 39696.0 36467.0 50631.0 True False 49780.07433519561 40580.83125457328 38668.341515015665 33023.14871104027 29682.713160987983 42171.14336879534 36176.51564433267 33561.895323333054 38394.57117114395 48858.424100877004 1.0188636913956883 0.8305800279351387 0.7914365276124731 0.6758946756624413 0.6075249807423728 0.8631294223023941 0.7404355811730593 0.6869213639399929 0.7858331879855858 1.0 15.576319710643052 -4.713261568544146 1.7860515554548626 0.7503343888469767 1.1397210321993478 0.33520096161826063 0.10373869024858132 1.119069540978582 3.1890772064637085 0.027264356358060106 0.7858678111413935 1.935256039452586e-05 4.713261568544146 0.38938664335237116 VTENGGSPQGIKS(ph)PSKPPGPNR ddPTM_PC-9_Lapatinib_30min_R1 2 VTENGGSPQGIKSPSKPPGPNR 22 2 Q92766;Q92766-2;Q92766-5;Q92766-3;C9JU34;Q92766-6;C9JE09;C9JPJ6 Q92766 RREB1 Ras-responsive element-binding protein 1 1 VTENGGS(0.001)PQGIKS(0.785)PS(0.214)KPPGPNR;VTENGGS(0.001)PQGIKS(0.702)PS(0.296)KPPGPNR 54.833999999999996 0.0044103 30375000.0 174766.0 128962.0 122420.0 105190.0 106431.0 125340.0 115517.0 118801.0 121308.0 105314.0 True False 172273.80479184064 128663.39641240187 112355.10015486585 112926.02350355334 100170.9378313968 119979.50038181074 121497.90503097794 124320.92816437317 107645.01561012899 123517.3845779159 1.3947332626944406 1.041662247399999 0.909629851205206 0.9142520616789661 0.810986552004006 0.9713571963315542 0.9836502403783974 1.006505510047862 0.8714968826289026 1.0 16.914354584095058 -4.762813645311728 2.611135186498442 0.9322791403792962 1.5035619422848077 0.8500228108435443 0.058157729330924335 0.19321374026146657 1.6489987638345938 0.01577762360457969 0.2512801266962847 1.726578603669457e-05 4.762813645311728 0.5712828019055115 VTENGGSPQGIKSPS(ph)KPPGPNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTENGGSPQGIKSPSKPPGPNR 22 2 Q92766;Q92766-2;Q92766-5;Q92766-3;C9JU34;Q92766-6;C9JE09;C9JPJ6 Q92766 RREB1 Ras-responsive element-binding protein 1 1 VTENGGS(0.002)PQGIKS(0.078)PS(0.92)KPPGPNR 40.996 0.034480000000000004 9062800.0 34392.0 29768.0 24048.0 38872.0 46826.0 43672.0 45076.0 45009.0 37056.0 31704.0 True False 40213.886327037086 32723.17031014167 24621.39552254786 36694.127864724374 37650.78144325357 41381.76343983785 40806.07495802087 43827.561440977486 37597.87389693546 37451.68423127411 1.073753748395016 0.8737436241336276 0.657417577551498 0.9797724352829736 1.0053161083691184 1.1049373156169549 1.0895658178156291 1.1702427364903176 1.0039034203310748 1.0 15.192742978806782 -6.221204063962077 2.5833166827949983 1.0801678780113257 0.8670654967279616 0.3807611566657614 0.1076211655999647 0.2785092167227194 3.6704724338220935 0.03559646384990751 0.046287402880496674 6.008913275453764e-07 6.221204063962077 -0.21310238128336412 VTENLASLT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 VTENLASLTPK 11 0 Q96DF8 Q96DF8 DGCR14 Protein DGCR14 1 VTENLAS(0.001)LT(0.999)PK;VTENLAS(0.002)LT(0.998)PK 120.6 0.0020788 19231500.0 140749.0 124775.0 125553.0 141188.0 141153.0 130654.0 133299.0 118454.0 125269.0 139550.0 True False 185504.2542389319 165106.07864188668 123888.08518512701 108639.28793285522 121556.34242813467 122484.18472582677 145162.3527656201 100149.65610212841 131890.46359826784 134664.3969757144 1.3775300554933316 1.226055901558466 0.9199765340164052 0.8067409825660706 0.902661320720549 0.9095513548983238 1.0779564311404366 0.7436980995072482 0.9794011376448164 1.0 17.03900895110256 -5.142220294327756 2.9174431305649873 0.9075310957612035 1.3598251327736472 0.7517563197757519 0.09008550222778579 0.12479136319269979 1.9632441042825879 0.023412859090237416 0.08683813449877455 7.207417927391288e-06 5.142220294327756 0.45229403701244375 VTENLASLT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VTENLASLTPK 11 0 Q96DF8 Q96DF8 DGCR14 Protein DGCR14 1 VTENLASLT(1)PK;VTENLAS(0.001)LT(0.999)PK 145.52 0.00050292 12927200.0 99995.0 97535.0 82368.0 103696.0 105665.0 93334.0 94629.0 87872.0 79064.0 66593.0 True False 116922.17850872489 107217.63021364117 84331.96550237949 97886.24930696787 84960.70177254938 88439.40073488335 85665.05606536879 85565.45310808007 80220.16142560738 78665.78375010205 1.4863155610341605 1.3629512743970096 1.0720285425525946 1.244330694243428 1.0800210424705665 1.124242288309606 1.0889747992278491 1.087708645729587 1.0197592600163132 1.0 16.263448641101533 -1.5228787453003165 0.4725030726018316 1.0561726621721963 12.938286849085408 0.8336770146306764 0.06125852802387749 35.557080510579276 0.40611345770616747 0.034776557983328064 413.2041607865992 0.0299999999986199 1.5228787453003165 11.882114186913212 VTENLASLT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 VTENLASLTPK 11 0 Q96DF8 Q96DF8 DGCR14 Protein DGCR14 1 VTENLASLT(1)PK;VTENLAS(0.027)LT(0.973)PK 133.98 0.00013947 19224800.0 174005.0 147106.0 154149.0 147245.0 142500.0 149260.0 132229.0 127818.0 134609.0 112245.0 True False 171523.65679139138 146765.38509516563 141475.4642523475 158073.88849492065 134118.43016577917 142876.49774205402 139075.17061853388 133756.89090255022 119447.91692438956 131646.3986929388 1.3029118798111985 1.1148454234398877 1.0746626239456403 1.2007460140525619 1.0187778131220004 1.0853050228537515 1.0564297390536483 1.0160315225525773 0.9073390393534287 1.0 17.006308530124606 -1.5228787452883026 0.23848066114435873 0.9648669895855194 2.6549568626924387 0.660747991270295 0.06111459221463349 32.531048113890755 0.4333556851945578 0.08518435733341838 21.71443678045614 0.029999999999449797 1.5228787452883026 1.6900898731069192 VTFFEPGS(ph)GDENGTSNKEDEFR ddPTM_PC-9_AZD4547_30min_R2 3 VTFFEPGSGDENGTSNKEDEFR 22 1 O95793-2;O95793-3;O95793;Q5JW30 O95793-2 STAU1 Double-stranded RNA-binding protein Staufen homolog 1 1 VTFFEPGS(0.782)GDENGT(0.155)S(0.063)NKEDEFR;VT(0.004)FFEPGS(0.876)GDENGT(0.093)S(0.028)NKEDEFR;VTFFEPGS(0.991)GDENGT(0.007)S(0.002)NKEDEFR 73.127 0.0005612 40599600.0 71494.4 71865.5 88394.7 102393.7 100290.4 86983.9 73647.0 85990.5 79779.4 94110.1 True False 94228.13202409864 95094.61746855149 87222.52852192901 78788.41443189511 86366.8090983159 81544.78298232604 80201.44032685629 72702.6440901115 83996.37621112686 90815.33404388496 1.037579534515223 1.0471207144665529 0.9604383383072754 0.8675673030484253 0.9510157068472668 0.8979186592312804 0.8831266346286886 0.8005547174993508 0.9249140257584368 1.0 16.470648294701107 -5.460386877608613 3.045936850614298 0.8962493132651844 1.0426399109466356 0.5434209549085532 0.05009877420326945 0.17912710229947318 3.23679710572937 0.013682168470063304 0.03130607477731161 3.464281083488717e-06 5.460386877608613 0.14639059768145113 VTFFEPGS(ph)GDENGTSNKEDEFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VTFFEPGSGDENGTSNKEDEFR 22 1 O95793-2;O95793-3;O95793;Q5JW30 O95793-2 STAU1 Double-stranded RNA-binding protein Staufen homolog 1 1 VT(0.001)FFEPGS(0.885)GDENGT(0.095)S(0.019)NKEDEFR;VT(0.001)FFEPGS(0.972)GDENGT(0.013)S(0.013)NKEDEFR;VTFFEPGS(0.992)GDENGT(0.004)S(0.004)NKEDEFR 65.78399999999999 0.0013609000000000002 31956900.0 44593.8 43987.0 49255.0 55454.0 48360.6 49730.0 46160.0 45939.7 50175.0 40792.0 True False 52142.64957230245 48353.73866004438 50429.42600062769 52347.09216429374 38884.68758947184 47122.071255338364 41787.39063054051 44733.831552135634 50908.714453225875 48187.26669070566 1.0820835700639502 1.0034546879449966 1.046530120172898 1.0863262384290915 0.8069494341535645 0.9778946699300387 0.8671874024056326 0.9283330353486074 1.056476491600739 1.0 15.556364349467357 -6.224593532082281 24.996538076461913 0.9341968402519025 1.0503692032405623 0.4047843427343898 0.06813432447056526 581.4101791085045 394433.6009834392 0.019636059024187413 0.02534940225665362 5.962199007623313e-07 6.224593532082281 0.11617236298865974 VTFFEPGS(ph)GDENGTSNKEDEFR ddPTM_PC-9_Lapatinib_30min_R1 1 VTFFEPGSGDENGTSNKEDEFR 22 1 O95793-2;O95793-3;O95793;Q5JW30 O95793-2 STAU1 Double-stranded RNA-binding protein Staufen homolog 1 1 VT(0.001)FFEPGS(0.963)GDENGT(0.028)S(0.008)NKEDEFR 63.906000000000006 0.017096 0.0 7822.2 6868.1 7497.4 7242.8 7360.4 7438.0 6586.1 7612.5 7419.1 6847.4 True False 7710.653993584199 6852.197336424811 6880.992712800934 7775.459673272516 6927.475743103168 7119.894078824862 6927.096031965204 7966.204540797557 6583.482831413493 8030.96396641302 0.9601156256996773 0.8532222738244089 0.8568078180376006 0.9681851027835425 0.8625957944868331 0.8865553510888081 0.8625485135950807 0.9919362823832483 0.8197624667408344 1.0 12.971357451246025 -11.519375799651419 2.9572697221328568 1.1014612407600068 0.8960893771233898 0.24569186951584865 0.054797734797357084 79234664.62569885 49820261846.56782 16510689.852982543 0.01281206153700922 3.0242953404916704e-12 11.519375799651419 -0.20537186363661708 VTFFEPGSGDENGT(ph)SNKEDEFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTFFEPGSGDENGTSNKEDEFR 22 1 O95793-2;O95793-3;O95793;Q5JW30 O95793-2 STAU1 Double-stranded RNA-binding protein Staufen homolog 1 1 VTFFEPGS(0.107)GDENGT(0.447)S(0.447)NKEDEFR 65.78399999999999 0.0020791 5966700.0 10065.0 11248.0 12308.0 15134.0 13232.0 11380.0 13916.0 12904.0 13138.0 9900.7 True False 11768.80570718854 12364.627104557683 12601.469398349931 14286.091045089996 10639.28458670678 10783.21276665494 12597.775736884782 12565.283672918156 13330.118395345919 11695.618536101923 1.0062576571611586 1.0572016406306919 1.077452155219652 1.2214908515519574 0.9096812241152992 0.9219873864190613 1.0771363393905238 1.074358199537011 1.139753178012658 1.0 13.513680541827197 -12.46784291106521 15.743054634953523 1.012026271259519 1.0498683965710298 0.0 0.08949090568325666 0.0 0.0 0.0 0.021392389054512607 3.4053134123626363e-13 12.46784291106521 0.03784212531151088 VTFFEPGSGDENGT(ph)SNKEDEFR ddPTM_PC-9_Lapatinib_30min_R1 1 VTFFEPGSGDENGTSNKEDEFR 22 1 O95793-2;O95793-3;O95793;Q5JW30 O95793-2 STAU1 Double-stranded RNA-binding protein Staufen homolog 1 1 VTFFEPGS(0.026)GDENGT(0.487)S(0.487)NKEDEFR 80.596 0.00035163 13115000.0 70058.0 64087.0 58354.0 57241.0 67133.0 56976.0 53683.0 63543.0 66163.0 51854.0 True False 69058.96007293633 63938.61048899358 53556.35937295402 61450.69409037833 63184.368928556156 54539.26929754302 56462.44306706368 66495.43975512634 58711.026212722696 60816.894808888115 1.1355226255787672 1.051329744636177 0.8806164724662496 1.0104214344300524 1.038927901977035 0.8967782631607221 0.9284006236176983 1.0933711752973012 0.9653736251615126 1.0 15.892184536625457 -4.989354253752776 5.3293752295570584 0.9779286340044504 1.1205418784031234 0.39944371047725746 0.06130278678593586 0.16345519080245025 15.045711610497657 0.015751793747196752 0.059044602366511385 1.024815643703973e-05 4.989354253752776 0.14261324439867296 VTGPPPGT(ph)PQPR ddPTM_PC-9_AZD4547_30min_R2 1 VTGPPPGTPQPR 12 0 F5GYK2;Q9NRL3;Q9NRL3-3;R4GN16;M0QZM0 F5GYK2 STRN4 Striatin-4 1 VTGPPPGT(1)PQPR 128.35 0.00050667 13437000.0 35497.0 47881.0 47761.0 48947.0 50944.0 55183.0 38374.0 64971.0 54339.0 53050.0 True False 46784.30761653267 63357.596886012216 47127.657933516966 37663.02537361155 43871.3049574496 51732.39828650707 41789.211659711706 54931.224835053166 57211.24860473285 51192.73564716328 0.9138856719630124 1.237628661275167 0.9205926844452281 0.7357103483040479 0.8569830153212494 1.0105417816125968 0.8163113600284292 1.0730277282631808 1.1175657616551513 1.0 15.643651482951254 -7.802711439417004 24.379839022203605 1.0714730840362896 0.9321698827142662 0.18966673649025123 0.1283836204322811 214.63421481747272 126783.26115052633 0.07515298822781873 0.03610302823220397 1.575029021751407e-08 7.802711439417004 -0.13930320132202345 VTGPPPGT(ph)PQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VTGPPPGTPQPR 12 0 F5GYK2;Q9NRL3;Q9NRL3-3;R4GN16;M0QZM0 F5GYK2 STRN4 Striatin-4 1 VT(0.024)GPPPGT(0.976)PQPR;VTGPPPGT(1)PQPR 91.62 0.015416999999999998 17583300.0 40992.0 39490.0 40396.0 35012.0 67237.0 50361.0 66750.0 51786.0 57856.0 63049.0 True False 47931.13597109512 43410.30621968201 41359.19384268313 33050.39115043554 54062.39251484309 47719.98050452635 60426.956771849545 50426.67237180251 58702.03454720151 74479.28460439068 0.6435498974740353 0.5828507409847342 0.5553113736573799 0.44375280087595215 0.7258715332995562 0.6407148075870909 0.811325687307787 0.6770563471393732 0.7881659290768877 1.0 16.184551594999128 -8.383086325515505 0.3625562800938514 1.025205953094218 0.544500875636008 0.7255293321207978 0.0771144607358202 0.7689078477600865 0.29672465968404144 0.13501718593120784 0.08268536351028442 4.139173915185492e-09 8.383086325515505 -0.4807050774582099 VTGPPPGT(ph)PQPR ddPTM_PC-9_Lapatinib_30min_R1 1 VTGPPPGTPQPR 12 0 F5GYK2;Q9NRL3;Q9NRL3-3;R4GN16;M0QZM0 F5GYK2 STRN4 Striatin-4 1 VT(0.001)GPPPGT(0.999)PQPR 108.97 0.0033455 8466700.0 8579.7 13878.0 10501.0 9844.6 34206.0 37411.0 37971.0 37043.0 30415.0 47551.0 True False 8457.351904675714 13845.866343661783 9637.648315032227 10568.604724622886 32194.070331583476 35811.018739300474 39936.95258647009 38764.15301212004 26989.342415851155 55770.12699227521 0.15164663164290718 0.24826671715450085 0.17281022717353953 0.18950297040002717 0.5772637085090861 0.642118292903667 0.7160993660997367 0.6950701944338286 0.4839390525251894 1.0 15.76720493564396 -6.352939371775508 2.876799878576377 0.6862967473737303 0.18777852440007892 0.8008515990532097 0.12203718053708026 0.11748606821930674 1.89019177783033 0.03838489890852489 0.04521223504181972 4.4367057675113503e-07 6.352939371775508 -0.49851822297365134 VTGT(ph)TGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTGTTGTR 8 0 A0A1B0GUM4 A0A1B0GUM4 1 VT(0.001)GT(0.461)T(0.461)GT(0.078)R 88.177 0.027313999999999998 9482600.0 27731.0 36596.0 38995.0 38662.0 46008.0 29948.0 50713.0 42986.0 42574.0 29502.0 True False 32425.310587783944 40229.00902546168 39924.78868936105 36495.89348389517 36993.06267119147 28377.474159559097 45909.09750967502 41857.66304743178 43196.56420790509 34850.47906229649 0.9304121911731122 1.1543315933634908 1.1456022919511106 1.0472135381168632 1.0614793158241824 0.8142635316098048 1.3173161099912243 1.2010642084032674 1.239482651893814 1.0 15.088890867380568 -7.290541806830257 24.99107584034076 1.2062210734225052 1.0394787466785353 0.3021993872696169 0.1198402553565914 905.2252089045352 777338.8022865705 0.04965385893800521 0.03348232136294207 5.122219594670195e-08 7.290541806830257 -0.16674232674396983 VTGTEGSSSTLVDYTS(ph)TSSTGGSPVRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTGTEGSSSTLVDYTSTSSTGGSPVRK 27 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 VTGTEGSSSTLVDY(0.027)T(0.069)S(0.151)T(0.151)S(0.151)S(0.151)T(0.151)GGS(0.151)PVRK 60.38399999999999 0.00090022 19630000.0 6097.0 6060.6 7571.2 7442.6 6252.7 6504.2 8087.6 10478.0 7331.1 4181.7 True False 7129.101678760902 6662.256314889965 7751.7261219358925 7025.615251234762 5027.528320382514 6163.10830201029 7321.483978846607 10202.963602358688 7438.303468421406 4939.809107681013 1.4431937597903757 1.3486869977486948 1.5692359670098528 1.4222442807173428 1.0177576118407297 1.2476409852411388 1.482139050163351 2.065457061183576 1.5057876339503549 1.0 12.270239576528093 -7.523484707859741 24.999751827447767 1.626132983236346 1.3430826315754996 0.04952359989927546 0.27963229110963245 38.24410739958278 1577569.5951994376 0.12773962287935997 0.0746154100043172 2.9958170776466616e-08 7.523484707859741 -0.28305035166084647 VTGTEGSSSTLVDYTST(ph)SSTGGSPVRK ddPTM_PC-9_Lapatinib_30min_R1 1 VTGTEGSSSTLVDYTSTSSTGGSPVRK 27 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 VTGTEGSSSTLVDY(0.004)T(0.045)S(0.106)T(0.365)S(0.284)S(0.066)T(0.066)GGS(0.066)PVRK 77.52199999999999 3.3842e-05 8836000.0 12363.0 17040.0 22390.0 22036.0 24099.0 24941.0 19022.0 23690.0 26709.0 15270.0 True False 12186.701352903474 17000.544926934483 20549.18062789939 23656.600949941076 22681.544200456934 23874.331570310667 20006.866084639183 24790.723884596926 23700.75116176126 17909.399154003964 0.6804639981559024 0.9492526678726522 1.1473964286124727 1.3209042216612958 1.2664603656112088 1.3330615597437916 1.117115427078205 1.3842297930500096 1.3233694194851053 1.0 14.128429316422206 -4.979726938081606 1.5197163478029887 1.2644651858053795 0.5788314051650049 0.7281359575780091 0.11005314212067635 0.3586522330425201 1.0318273802885423 0.03020768648004183 0.33215823877592915 1.0477871353693904e-05 4.979726938081606 -0.6856337806403746 VTGTEGSSSTLVDYTSTS(ph)STGGSPVRK ddPTM_PC-9_AZD4547_30min_R2 1 VTGTEGSSSTLVDYTSTSSTGGSPVRK 27 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 VTGTEGSSSTLVDYT(0.002)S(0.061)T(0.16)S(0.423)S(0.213)T(0.059)GGS(0.082)PVRK 85.728 3.8075e-07 9381000.0 4828.0 4520.7 4754.3 7078.8 9313.1 9322.1 5928.3 6745.1 5142.6 7333.1 True False 6363.203571361521 5981.9278678932205 4691.254875595568 5446.892026369777 8020.136820807628 8739.18761333468 6455.907215361148 5702.799781978377 5414.427337174019 7076.370401021928 0.899218555665569 0.8453384332495294 0.6629464838242617 0.7697296378922123 1.1333687139454158 1.2349816527513338 0.9123190067084141 0.8058933406248509 0.7651418778745809 1.0 12.78879385017657 -6.227517103890396 24.595275524551607 0.9754154162465144 0.7885702513033369 0.28032512960649536 0.14193805817300598 786.1011869213269 569960.6049818512 0.0476377281101062 0.061496569555573394 5.922197629293592e-07 6.227517103890396 -0.1868451649431775 VTGTEGSSSTLVDYTSTS(ph)STGGSPVRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTGTEGSSSTLVDYTSTSSTGGSPVRK 27 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 VTGTEGSSSTLVDY(0.013)T(0.034)S(0.085)T(0.085)S(0.218)S(0.218)T(0.218)GGS(0.13)PVRK 44.183 0.019014 44900000.0 6948.1 6539.3 5747.0 8425.8 6192.7 6745.8 8196.9 8141.3 7269.9 5537.3 True False 8124.276098769663 7188.478487271879 5884.03027561887 7953.729742812167 4979.284889668909 6392.038372697797 7420.430291583133 7927.599501420377 7376.208534200429 6541.168656757319 1.2420221102810005 1.0989593548923189 0.8995380771202719 1.2159493448614278 0.7612225201570191 0.9772012782600455 1.1344196551051313 1.2119546089414486 1.127659126566088 1.0 12.67533269786038 -9.72185949453509 11.516915800120522 0.9999767153884938 1.0678242078797082 0.021141883734773548 0.14580172804783392 0.0 0.0 0.1452332510461224 0.03522423731852996 1.8973196537645795e-10 9.72185949453509 0.06784749249121447 VTGTEGSSSTLVDYTSTS(ph)STGGSPVRK ddPTM_PC-9_Lapatinib_30min_R1 1 VTGTEGSSSTLVDYTSTSSTGGSPVRK 27 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 VTGTEGSSSTLVDYT(0.007)S(0.069)T(0.069)S(0.432)S(0.109)T(0.109)GGS(0.205)PVRK 99.54899999999999 8.7018e-10 8443700.0 8263.8 9082.0 13982.0 10812.0 13671.0 15392.0 9856.7 11763.0 14116.0 11304.0 True False 8145.956696604677 9060.971186996421 12832.453932080809 11607.150547774674 12866.898658220134 14733.720040504468 10367.031696796503 12309.551922942735 12526.10743193013 13257.881338366797 0.6144237143706519 0.683440359416629 0.9679113581251592 0.8754906045345952 0.9705094147271327 1.111317839138201 0.7819523672153782 0.928470515671331 0.9448046118561194 1.0 13.694562625071933 -5.190381212597255 4.04047628126991 0.9437250105909951 0.6304247841289875 0.6894554793644279 0.0804788306261251 0.1264407115791452 3.9879111170969206 0.021167221649085174 0.06223716557289172 6.450877389145896e-06 5.190381212597255 -0.3133002264620076 VTGTEGSSSTLVDYTSTSS(ph)TGGSPVR ddPTM_PC-9_Lapatinib_30min_R1 1 VTGTEGSSSTLVDYTSTSSTGGSPVR 26 0 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 VTGTEGSSSTLVDYT(0.001)S(0.005)T(0.064)S(0.152)S(0.498)T(0.083)GGS(0.196)PVR 97.59299999999999 0.00031374 0.0 7099.6 6955.4 8835.8 6148.1 8992.8 5927.1 6603.6 8489.8 8215.2 5642.6 True False 6998.358402092816 6939.295198638501 8109.354631174335 6600.251783460373 8463.861184525054 5673.611749744938 6945.502096337049 8884.267101538664 7289.917666108844 6617.915891708108 1.0574867551371243 1.0485620113929015 1.2253638099775368 0.9973308654058498 1.2789315130356698 0.8573109484291978 1.049499904500054 1.342456937639563 1.1015428097602025 1.0 12.692161240956436 VTGTEGSSSTLVDYTSTSS(ph)TGGSPVRK ddPTM_PC-9_AZD4547_30min_R2 1 VTGTEGSSSTLVDYTSTSSTGGSPVRK 27 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 VTGTEGSSSTLVDYT(0.004)S(0.025)T(0.064)S(0.163)S(0.274)T(0.274)GGS(0.195)PVRK 76.749 2.0424e-05 60462000.0 12796.0 11773.0 22847.0 24484.0 17675.0 18645.0 20498.0 18859.0 18978.0 21373.0 True False 16864.8618266657 15578.39201643703 22544.033852035398 18839.592074029173 15221.131342708088 17479.125202542888 22322.282290112315 15944.774886707411 19981.13833564512 20624.737775434885 0.817700666563267 0.7553255797022393 1.0930579626028745 0.9134463807083205 0.7380036298370412 0.8474835119291271 1.082306235025169 0.7730898235078872 0.9687947819362666 1.0 14.332088156484406 -14.522878518927145 0.05136666782766638 1.4367416360170282 0.6743097749626494 0.10572921697033899 0.1189500923455436 1472.574295649753 5.5640766502388574 87.39164997931483 18.69034194032208 3.000001563592867e-15 14.522878518927145 -0.7624318610543788 VTGTEGSSSTLVDYTSTSSTGGS(ph)PVRK ddPTM_PC-9_AZD4547_30min_R2 2 VTGTEGSSSTLVDYTSTSSTGGSPVRK 27 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 VTGTEGSSSTLVDYT(0.006)S(0.017)T(0.069)S(0.136)S(0.136)T(0.136)GGS(0.499)PVRK;VTGTEGSSSTLVDYTS(0.002)T(0.002)S(0.027)S(0.027)T(0.108)GGS(0.833)PVRK 104.84 3.0774e-10 80929000.0 29270.1 37777.4 45807.0 51737.0 53761.0 45144.0 44631.0 54944.0 35252.0 46368.0 True False 38577.38294409875 49988.205772678855 45199.5692502379 39809.83397868187 46297.213132409044 42321.13854350207 48603.072538296554 46453.66728751539 37115.348751615624 44744.6704333208 0.8621671043836909 1.1171879307318187 1.0101665474907229 0.8897111900289242 1.0346978239878168 0.9458364121056536 1.0862315459608893 1.0381944226573612 0.8294920577619516 1.0 15.449428231818695 -8.239467026807986 24.91730908253796 0.9147459739042433 1.0012136795681827 0.13170807525705397 0.08521553029198552 1263.5178175507742 1432871.9250677263 0.05514323673163464 0.020805741735742053 5.761465600090018e-09 8.239467026807986 0.08646770566393946 VTGTEGSSSTLVDYTSTSSTGGS(ph)PVRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VTGTEGSSSTLVDYTSTSSTGGSPVRK 27 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 VTGTEGSSSTLVDYTS(0.019)T(0.055)S(0.217)S(0.056)T(0.056)GGS(0.597)PVRK;VTGTEGSSSTLVDYTS(0.002)T(0.021)S(0.057)S(0.248)T(0.248)GGS(0.422)PVRK 127.65 5.9613e-11 82554000.0 27603.0 36334.0 34639.0 45917.0 48906.0 40988.0 47295.0 37826.0 34533.0 27286.0 True False 32275.64271589916 39940.99939695939 35464.92512913906 43344.419354922524 39323.220374658544 38838.51712474982 42814.87521385209 36833.107579959884 35037.97979498254 32232.73580414286 1.0013311594776508 1.2391439448284682 1.100276605269751 1.3447328709017459 1.2199777460281342 1.2049401379003617 1.3283041028229787 1.1427235901963289 1.0870308995142486 1.0 14.976239024154292 -8.343701467783589 2.2290873529954176 1.0081349953940548 1.2088571733100757 0.3182508648522767 0.09551890066697194 0.3342595332435663 3.1967955161570587 0.08836558810187328 0.024955381291451396 4.532090068365712e-09 8.343701467783589 0.20072217791602087 VTGTEGSSSTLVDYTSTSSTGGS(ph)PVRK ddPTM_PC-9_Lapatinib_30min_R1 2 VTGTEGSSSTLVDYTSTSSTGGSPVRK 27 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 VTGTEGSSSTLVDYTS(0.003)T(0.026)S(0.069)S(0.069)T(0.069)GGS(0.764)PVRK;VTGTEGSSSTLVDYT(0.001)S(0.013)T(0.032)S(0.203)S(0.203)T(0.203)GGS(0.347)PVRK 103.99 3.3681000000000005e-10 144716000.0 35402.0 36863.0 48196.0 45632.0 40886.0 47385.0 44426.0 40674.0 46932.0 40358.0 True False 34897.160988068325 36777.64598835597 44233.510921940106 48987.929503889616 38481.16586496877 45358.454009830035 46726.16090191255 42563.862527737205 41646.02394413045 47333.82652634529 0.737256282642712 0.7769844250366298 0.9345010570256854 1.034945473436923 0.8129739065898408 0.9582672126578273 0.9871621276151312 0.8992271627151631 0.8798364087668024 1.0 15.53058393563024 -5.219945755848002 4.277220088159023 0.9366721342690378 0.7490353457509843 0.5897630163969947 0.06074510253291042 0.14419087940793354 5.9496471692449155 0.015722149227332838 0.04380513434277504 6.026348515369644e-06 5.219945755848002 -0.18763678851805354 VTHAVVTVPAYFNDAQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTHAVVTVPAYFNDAQR 17 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 86.411 0.0025765999999999996 7663700.0 24986.0 23827.0 25312.0 25789.0 31117.0 21784.0 21126.0 22615.0 19451.0 22440.0 False True 29215.636304005235 26192.38709284282 25915.534076294556 24344.12593906607 25019.84722525354 20641.608691459704 19124.792341005174 22021.38021257317 19735.434077323294 26508.194365057738 1.1021360376969456 0.9880864283750987 0.9776423742559995 0.9183622846509578 0.9438533187395785 0.778687842981445 0.7214671839819792 0.8307385976315708 0.7445031451609514 1.0 14.694150782334953 -5.970760873709549 0.9015551898872538 0.8021200248030426 1.059876823165046 0.5425097231150013 0.08073352753221857 0.47889863004518624 0.7787442340604083 0.035519956343441766 0.08409127100638876 1.0696436721493142e-06 5.970760873709549 0.2577567983620034 VTHAVVTVPAYFNDAQR ddPTM_PC-9_Lapatinib_30min_R1 1 VTHAVVTVPAYFNDAQR 17 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 74.993 0.0077687 8958100.0 30107.0 27755.0 33664.0 23770.0 29919.0 26907.0 20533.0 24792.0 28153.0 23526.0 False True 29677.668659052382 27690.735002762114 30896.275866797896 25518.1250943955 28159.2232430172 25756.250333280525 21596.098271259398 25943.92682764571 24982.11267576716 27592.437753575457 1.0755725508597629 1.0035624706328792 1.1197370867600969 0.9248231461929758 1.020541334350507 0.9334532368363503 0.7826817791211997 0.9402549734585836 0.9053970837545859 1.0 14.751985301975738 -6.321232956256391 1.2115396784827523 0.9021591178808013 1.0549018838576742 0.4244334037124753 0.06856005695240099 0.42425202348382446 1.2825396580273813 0.02829575802570503 0.03884040384801179 4.772731948763599e-07 6.321232956256391 0.15274276597687297 VTIAQGGVLPNIQAVLLPK ddPTM_PC-9_Lapatinib_30min_R1 2 VTIAQGGVLPNIQAVLLPK 19 0 A0A0U1RR32;A0A0U1RRH7;Q99878;Q96KK5;Q93077;Q7L7L0;Q6FI13;P20671;P0C0S8;P04908;Q9BTM1;Q16777;H0YFX9 A0A0U1RR32 HIST1H2AJ;HIST1H2AH;HIST1H2AC;HIST3H2A;HIST2H2AA3;HIST1H2AD;HIST1H2AG;HIST1H2AB;H2AFJ;HIST2H2AC Histone H2A type 1-J;Histone H2A type 1-H;Histone H2A type 1-C;Histone H2A type 3;Histone H2A type 2-A;Histone H2A type 1-D;Histone H2A type 1;Histone H2A type 1-B/E;Histone H2A.J;Histone H2A type 2-C;Histone H2A 0 ; 180.11 2.2917e-08 44571000.0 130435.0 142436.0 150525.0 135320.0 158863.0 149868.0 169579.0 130429.0 141564.0 144905.0 False True 128574.97298115054 142106.19819324173 138149.41554330307 145271.8842142867 149518.9906766752 143458.49499937144 178358.97086358027 136489.20749447437 125619.57158499262 169951.63617622465 0.7565386004747244 0.8361566936954364 0.8128748781215291 0.8547836754195925 0.879773764117442 0.8441136444877636 1.0494689835091553 0.8031061692924643 0.7391489391413469 1.0 17.374764725648333 -2.7439701033285315 0.45235476473455033 0.8866993098525369 2.0533678008231943e-14 0.18130471678650883 0.08461219669180518 56.59552049354398 2.0028072988259424 0.054681712977380066 39.65599171959117 0.001803141864206083 2.7439701033285315 -0.8866993098525163 VTIPPPSSSVAISNHVT(ph)PPPIPK ddPTM_PC-9_AZD4547_30min_R2 2 VTIPPPSSSVAISNHVTPPPIPK 23 0 A0A1W2PRW5;F5H2U7;A0A1W2PNT6;F5GYH1;A0A1W2PRM0;A0A1W2PRL5;A0A1W2PR09;Q8NC96 A0A1W2PRW5 NECAP1 Adaptin ear-binding coat-associated protein 1 1 VTIPPPSSSVAISNHVT(1)PPPIPK;VTIPPPS(0.002)S(0.002)S(0.001)VAIS(0.006)NHVT(0.989)PPPIPK 106.1 4.6513e-06 22019900.0 19358.9 15255.7 122088.0 273287.0 189497.0 147876.0 78946.0 210159.0 104859.0 161452.0 True False 25514.627509865473 20186.806683526585 120469.03334911776 210284.9043920607 163188.61250631732 138629.29034332177 85972.04106133335 177683.75552338615 110401.63266610865 155799.61462216437 0.1637656650932159 0.12956904118461643 0.7732306247436609 1.3497138930800998 1.0474262911501566 0.8897922544899548 0.551811641317775 1.1404633827515802 0.7086130022455311 1.0 17.249332139265277 -5.3284899423805685 4.0835763019225615 0.9517131606129995 0.138552243137508 0.6982093667452185 0.20892011474730995 0.11634563438779408 3.805127782779605 0.05748108733732565 0.13352201502911237 4.693643039760998e-06 5.3284899423805685 -0.8131609174754915 VTIPPPSSSVAISNHVT(ph)PPPIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTIPPPSSSVAISNHVTPPPIPK 23 0 A0A1W2PRW5;F5H2U7;A0A1W2PNT6;F5GYH1;A0A1W2PRM0;A0A1W2PRL5;A0A1W2PR09;Q8NC96 A0A1W2PRW5 NECAP1 Adaptin ear-binding coat-associated protein 1 1 VTIPPPS(0.061)S(0.061)S(0.061)VAIS(0.06)NHVT(0.758)PPPIPK 56.335 0.018177000000000002 4350800.0 6507.0 9443.6 35373.0 37017.0 52670.0 53644.0 36506.0 32585.0 40280.0 22343.0 True False 7608.506580891778 10381.09819742186 36216.426472849555 34943.05750073323 42349.6915947586 50830.81420513516 33047.887399447805 31729.67827666135 40869.01879772673 26393.609032909317 0.28827079204685435 0.3933186319642006 1.372166513025653 1.3239211605038133 1.604543415868371 1.9258758490267815 1.2521170317496744 1.2021727773984476 1.5484437443461598 1.0 14.687901016226625 -5.256054872434621 4.097417230412504 1.4350630772260415 0.3060734278972215 0.759568027044573 0.2392567483531324 0.09400644030052124 3.8471173306537034 0.06494110754914184 0.17045773730611316 5.54555641285579e-06 5.256054872434621 -1.12898964932882 VTIPPPSSSVAISNHVT(ph)PPPIPK ddPTM_PC-9_Lapatinib_30min_R1 2 VTIPPPSSSVAISNHVTPPPIPK 23 0 A0A1W2PRW5;F5H2U7;A0A1W2PNT6;F5GYH1;A0A1W2PRM0;A0A1W2PRL5;A0A1W2PR09;Q8NC96 A0A1W2PRW5 NECAP1 Adaptin ear-binding coat-associated protein 1 1 VTIPPPSSSVAISNHVT(0.999)PPPIPK;VTIPPPSSSVAIS(0.004)NHVT(0.995)PPPIPK 108.49 5.9047e-05 4435700.0 54489.0 36973.2 134096.0 53751.0 87387.0 107523.0 54929.0 70454.0 129953.0 37922.6 True False 53711.976867941186 36887.59082702665 123071.14450552894 57704.027848079655 82247.06846945228 102924.49193835518 57772.95485033884 73727.55004497235 115316.32467424334 44477.47088131178 1.2076221017888293 0.8293545045639231 2.7670445748577865 1.2973765527734922 1.8491849208092057 2.3140814866252035 1.2989262587458286 1.6576380937152306 2.592690690124112 1.0 15.440787134096334 -5.213694387566482 24.993080325372947 1.848145069204632 1.0184876414948834 0.2649389085847845 0.5520866946206021 508.0235101187294 265933.39735711325 0.1322339976747377 0.3498566918827685 6.113720952759571e-06 5.213694387566482 -0.8296574277097486 VTKNEEPS(ph)EEEIDAPKPK ddPTM_PC-9_AZD4547_30min_R2 1 VTKNEEPSEEEIDAPKPK 18 2 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 VT(0.166)KNEEPS(0.834)EEEIDAPKPK 109.44 0.00069909 28665000.0 23769.0 14522.0 25190.0 32212.0 26002.0 19655.0 18679.0 17494.0 17945.0 22324.0 True False 31327.04757408699 19215.95250681208 24855.96414114639 24786.021070438954 22392.071127190717 18425.969742879086 20341.39481398225 14790.704272127874 18893.536064556407 21542.443554896752 1.4542012141870566 0.892004310367296 1.1538135902645292 1.1505668336684542 1.03943970284192 0.8553333188931918 0.944247330259733 0.6865843345225264 0.877037742557379 1.0 14.39489428331211 -6.616156179036609 2.312971008616903 0.8524806307992635 1.143786141461141 0.45635148341202003 0.14800762041360807 0.2743098811907981 2.9871409965486375 0.05247420316506878 0.05310216735244126 2.4201585636418853e-07 6.616156179036609 0.2913055106618775 VTKNEEPS(ph)EEEIDAPKPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VTKNEEPSEEEIDAPKPK 18 2 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 VT(0.433)KNEEPS(0.567)EEEIDAPKPK;VT(0.003)KNEEPS(0.997)EEEIDAPKPK 81.48 0.0087306 67541000.0 28893.0 14969.599999999999 14908.3 29429.0 29562.0 31999.0 29913.0 44457.0 31518.0 23933.4 True False 33784.014237237774 16455.682957360128 15263.770412042602 27780.18854010532 23769.538312592616 30320.91610897993 27079.424088634267 43290.050856085145 31978.89112380214 28272.33596330983 1.1949495181820375 0.5820418581158395 0.5398835961715729 0.9825926154866301 0.8407348562721991 1.0724588215253466 0.9578063915120543 1.531180547382587 1.1311018362721232 1.0 14.787103468358959 -6.961693229692621 1.251002736134582 1.2226918328244698 0.784857221690086 0.323191826048129 0.22584777269025277 0.4722133054811162 1.521216470599793 0.12323345132456313 0.09235336298554742 1.0922115637665081e-07 6.961693229692621 -0.4378346111343838 VTKNEEPS(ph)EEEIDAPKPK ddPTM_PC-9_Lapatinib_30min_R1 4 VTKNEEPSEEEIDAPKPK 18 2 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 VTKNEEPS(1)EEEIDAPKPK;VTKNEEPS(1)EEEIDAPKPK;VTKNEEPS(1)EEEIDAPKPK;VT(0.001)KNEEPS(0.999)EEEIDAPKPK 124.66 0.00012592 134453000.0 253345.0 141677.0 151881.0 137849.0 137673.0 144995.0 110176.0 107321.0 142668.0 111576.0 True False 249732.25384221674 141348.95561110924 139393.93045761433 147986.87531078336 129575.34481553224 138793.90184985346 115880.37418469165 112307.52545457253 126599.22747935742 130861.76293432541 1.9083668769428694 1.080139472689566 1.0651998515989036 1.13086414237788 0.9901696409252964 1.0606146420288476 0.8855174467032639 0.8582149814910827 0.9674271891239369 1.0 16.997684085978115 -2.7423294251586228 1.3072223993941932 0.9808467995706044 199.9999999952488 0.9164013950144765 0.08185007891151834 87.46648945885877 0.9279332445708919 0.02613943032698712 51432.61305092533 0.0018099666587590478 2.7423294251586228 199.0191531956782 VTKS(ph)PGETSKPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTKSPGETSKPR 12 2 Q9UNZ2-4;Q9UNZ2;Q9UNZ2-5;F2Z2K0;Q9UNZ2-6 Q9UNZ2-4 NSFL1C NSFL1 cofactor p47 1 VT(0.44)KS(0.559)PGETSKPR 45.653 0.043075 5578500.0 47388.0 34775.0 42821.0 48214.0 46209.0 48456.0 48693.0 45604.0 43260.0 32822.0 True False 55409.852444336866 38227.23218003146 43842.01503954685 45512.725891897004 37154.67816408204 45914.88205808716 44080.44653320858 44406.94332143207 43892.59566012062 38772.36878119098 1.4291067114583147 0.9859400748962243 1.1307541018957612 1.173844346440238 0.9582772302038534 1.184216582618525 1.1369036228344302 1.1453244853838929 1.1320586551682015 1.0 15.242741258163997 -1.5228787452868797 0.014334057631266344 0.0076102154730700354 2.4570887298985817 0.14771381678447537 0.11739460204490686 15031.540045933578 16.700132777980976 1152.7477216984437 1760.408944444805 0.029999999999548083 1.5228787452868797 2.4494785144255116 VTLATLK ddPTM_PC-9_Lapatinib_30min_R1 1 VTLATLK 7 0 P06748;P06748-3;P06748-2;E5RI98 P06748;E5RI98 NPM1 Nucleophosmin 0 108.09 0.045207 33006000.0 192310.0 210170.0 220370.0 204820.0 190200.0 189330.0 215840.0 183910.0 193550.0 183630.0 False True 189567.62413466518 209683.3642778066 202252.02925279975 219883.14605949083 179012.80994758758 181232.79724978647 227015.13908676876 192455.1299964635 171750.3608281437 215370.2008284048 0.8801943045300974 0.9735950631576503 0.9390901270224616 1.0209543623664152 0.8311865302582654 0.8414943040062578 1.05406940335094 0.8936014790170588 0.7974657597361159 1.0 17.716459123153072 -6.2588421498138045 24.99914648202958 0.9021308824973271 0.953870478281621 0.08853000277215062 0.07933288157834932 632.822283269279 6091113.800772236 0.02426209192588333 0.02985491621611256 5.510079312774953e-07 6.2588421498138045 0.05173959578429388 VTLELGGK ddPTM_PC-9_Lapatinib_30min_R1 2 VTLELGGK 8 0 P00352;H0Y2X5;H0YMG7;O94788-4;P05091-2;O94788-2;O94788-3;P47895;P30837;P05091;O94788 P00352 ALDH1A1;ALDH1A3;ALDH1A2;ALDH2;ALDH1B1 Retinal dehydrogenase 1;Retinal dehydrogenase 2;Aldehyde dehydrogenase, mitochondrial;Aldehyde dehydrogenase family 1 member A3;Aldehyde dehydrogenase X, mitochondrial 0 ; 143.61 0.0080031 137782000.0 719070.0 732040.0 783470.0 692220.0 757410.0 679560.0 781370.0 643350.0 632120.0 667880.0 False True 708815.9299387115 730345.0063564052 719056.1208816589 743128.1679782284 712860.6329253534 650496.802931732 821825.5153272266 673242.3896646429 560923.9890813038 783322.1681058401 0.9048842976737235 0.932368616762705 0.9179570681887075 0.9486877790975772 0.9100478218931675 0.8304332871169795 1.0491539098331557 0.8594706202335849 0.7160833842321611 1.0 19.57924626181908 -7.982880056969692 24.990338566460874 0.834620057759603 0.926025627838633 0.11747662446779261 0.08186641074654667 350.549961168396 511704.81869021815 0.04182828755474518 0.020086395246914503 1.0402074096390081e-08 7.982880056969692 0.09140557007902994 VTLLEGDHVR ddPTM_PC-9_Lapatinib_30min_R1 1 VTLLEGDHVR 10 0 O75534;O75534-2;O75534-4;O75534-3;E9PLT0 O75534 CSDE1 Cold shock domain-containing protein E1 0 129.88 0.00019448 3195200.0 13121.0 15927.0 16184.0 15806.0 16042.0 16426.0 15161.0 15533.0 14627.0 15581.0 False True 12933.892133903293 15890.12201005197 14853.413992046622 16968.425967270312 15098.441099785483 15723.498270876204 15945.962396657264 16254.71988600438 12979.55323086158 18274.155089622527 0.707769638074712 0.8695407219716333 0.8128098902083596 0.9285477705563685 0.8262182861936824 0.8604227223509346 0.8725964247568747 0.8894922805615819 0.7102683088331876 1.0 14.157517083883642 -11.988346111324732 2.3832494537714384 3.0836449091975244 0.8380184193493689 0.3469605063061125 0.06898979684861 5271321.8563898485 1139633.1473834014 58330413.1064758 0.016906823765143526 1.027197346114638e-12 11.988346111324732 -2.2456264898481555 VTLS(ph)FPS(ph)T(ph)LQTGTGT(ph)LK ddPTM_PC-9_AZD4547_30min_R2 1 VTLSFPSTLQTGTGTLK 17 0 E9PLK3;P55786-2;P55786;E9PJY4;E9PPD4;E9PP11;A6NEC2-3;A6NEC2 E9PLK3 NPEPPS;NPEPPSL1 Puromycin-sensitive aminopeptidase;Puromycin-sensitive aminopeptidase-like protein 4 VT(0.378)LS(0.633)FPS(0.995)T(0.995)LQT(0.006)GT(0.041)GT(0.953)LK 79.32600000000001 0.0040235 6645900.0 6216.0 6246.6 12434.0 15266.0 20716.0 17576.0 11232.0 10495.0 9188.3 5151.9 True False 8192.558699168023 8265.691291079209 12269.11703576872 11746.659557348856 17839.940984189026 16476.96994153358 12231.62624073283 8873.238901107923 9673.974779713768 4971.533549116316 1.6478936767155559 1.6626039449232772 2.467873728409123 2.362783925985335 3.588418102370053 3.3142630495699548 2.4603326357733195 1.7848092170041034 1.9458733777293538 1.0 12.279475227483479 -5.260879429204626 7.255942421964156 2.4751550207480593 1.651700566011525 0.12700102300987792 0.6992227989838607 0.21600380993648594 90.36416342881859 0.19040757912776995 0.4500272769634528 5.484292011791983e-06 5.260879429204626 -0.8234544547365343 VTLS(ph)FPS(ph)T(ph)LQTGTGT(ph)LK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTLSFPSTLQTGTGTLK 17 0 E9PLK3;P55786-2;P55786;E9PJY4;E9PPD4;E9PP11;A6NEC2-3;A6NEC2 E9PLK3 NPEPPS;NPEPPSL1 Puromycin-sensitive aminopeptidase;Puromycin-sensitive aminopeptidase-like protein 4 VT(0.434)LS(0.595)FPS(0.974)T(0.991)LQT(0.006)GT(0.028)GT(0.971)LK 66.893 0.012153 5137400.0 1006.9 2599.5 5295.3 4433.2 5578.9 9738.1 7440.2 4276.2 11109.0 3589.3 True False 1177.3482828184938 2857.561180502998 5421.560034537083 4184.822176628319 4485.754593468744 9227.41689305471 6735.4103936167085 4163.954281008419 11271.448108836792 4240.011677116834 0.2776757170676188 0.6739512525225193 1.2786662979720118 0.9869836442228754 1.0579580753699747 2.176271575584259 1.5885358122873663 0.9820619842820495 2.6583530818248278 1.0 12.049852522680597 -5.27178061388083 0.6547443550128577 1.653894101582725 3.926081132232103e-14 0.41992043763646203 0.5092793206935671 1.9645515640102622 0.9719459732522714 0.25247544531410954 2.2173085809889406 5.348344655839533e-06 5.27178061388083 -1.6538941015826858 VTLS(ph)FPS(ph)T(ph)LQTGTGT(ph)LK ddPTM_PC-9_Lapatinib_30min_R1 1 VTLSFPSTLQTGTGTLK 17 0 E9PLK3;P55786-2;P55786;E9PJY4;E9PPD4;E9PP11;A6NEC2-3;A6NEC2 E9PLK3 NPEPPS;NPEPPSL1 Puromycin-sensitive aminopeptidase;Puromycin-sensitive aminopeptidase-like protein 4 VT(0.491)LS(0.671)FPS(0.919)T(0.919)LQT(0.002)GT(0.004)GT(0.995)LK 73.168 0.0068673 5145600.0 6114.6 5029.2 13643.0 6660.9 18611.0 16142.0 11771.0 14342.0 19807.0 6153.0 True False 6027.40468271969 5017.555196393124 12521.325203502969 7150.764806111022 17516.33757063382 15451.644288839869 12380.44478405466 15008.381678045125 17576.12708304337 7216.537851642858 0.835221100010934 0.6952856479857399 1.7350875809031427 0.9908857894347686 2.427249455449914 2.1411436628607543 1.7155656962619865 2.079720495698424 2.4355345242237085 1.0 12.817091151939001 -5.591805113795937 1.1158272048150115 1.9914174449781568 0.6883014031693234 0.43727722310770467 0.47863569986403076 0.5400062212114484 1.2023810651299252 0.16359830184317337 0.5999612118277056 2.5597342896775196e-06 5.591805113795937 -1.3031160418088334 VTLTSEEEAR ddPTM_PC-9_AZD4547_30min_R2 1 VTLTSEEEAR 10 0 P00338-3;P00338;P00338-4 P00338-3 LDHA L-lactate dehydrogenase A chain 0 154.85 0.0011432 5686700.0 12430.0 9842.3 15437.0 18303.0 13761.0 12510.0 11552.0 14383.0 10029.0 8816.9 False True 16382.481439938629 13023.630998333314 15232.295293643381 14083.52612853111 11850.522682150277 11727.747722381953 12580.105620810684 12160.437838459775 10559.112465390703 8508.223014655501 1.92548801456187 1.5307110516379245 1.790302777372619 1.6552840827364412 1.392831694907107 1.378401541917835 1.4785820257815672 1.4292570631391885 1.2410479188430443 1.0 13.054642133889304 -1.5228787452937274 0.07751980741411608 0.5172591596209171 3.9804630839226043 0.8148622778495505 0.10851079699148189 88.37793145425788 0.5030442852235049 3.5190453407762843 32.90863971345485 0.029999999999075065 1.5228787452937274 3.463203924301687 VTLTSEEEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VTLTSEEEAR 10 0 P00338-3;P00338;P00338-4 P00338-3 LDHA L-lactate dehydrogenase A chain 0 ;;; 142.98 0.0005894 49797300.0 73017.0 72586.0 103844.0 101427.0 112506.0 93487.0 95747.0 87640.0 89153.0 58997.2 False True 85377.33594851327 79791.85837583781 106320.03479056318 95744.3740207709 90461.25693107881 88584.37714554222 86677.15101174964 85339.5428622556 90456.6939640945 69692.92533842177 1.2250502548706284 1.1449061434625774 1.525549892966666 1.3738033459758783 1.2979977019447544 1.2710669944673074 1.2437008575957198 1.2245079747744185 1.2979322294888036 1.0 16.08872459235474 -10.151779658699239 0.41321610552553395 0.9168690005827931 1.3112594036996252 0.4505726109357935 0.09666337984475455 9.827982146479103 1.4606166761511628 1.1972443881393164 0.06561708537104255 7.05050688945801e-11 10.151779658699239 0.39439040311683216 VTLTSEEEAR ddPTM_PC-9_Lapatinib_30min_R1 2 VTLTSEEEAR 10 0 P00338-3;P00338;P00338-4 P00338-3 LDHA L-lactate dehydrogenase A chain 0 ; 204.79 0.00033728 21205900.0 43219.0 56738.0 53854.0 50136.0 57274.0 53434.0 49565.0 43524.0 57307.0 51813.0 False True 42602.6891346061 56606.62664697236 49426.33200245172 53823.16868879312 53905.25592501645 51148.752380737795 52131.233176592395 45546.28393217375 50852.48219053698 60768.80801351722 0.7010617869142619 0.9315079314108147 0.8133503621044778 0.8857038742115999 0.8870546862302439 0.8416941857632032 0.8578617037378204 0.7495010256255574 0.8368188196027396 1.0 15.891043373096842 -4.743632183574586 24.969257538686385 0.8576763576782903 0.7010612943150177 0.36528947925094857 0.06458556720288099 1288.9952175032886 1807333.0011499324 0.01543125247919673 0.48217621230842456 1.804545415007439e-05 4.743632183574586 -0.15661506336327258 VTLYNTDQDGSDS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 VTLYNTDQDGSDSPR 15 0 C9JXI1;C9JVP0;Q9UPW0-2;Q9UPW0 C9JXI1 FOXJ3 Forkhead box protein J3 1 VTLYNTDQDGS(0.004)DS(0.996)PR 161.2 1.3672e-14 0.0 36962.0 32877.0 42231.0 48522.0 41295.0 40538.0 29171.0 30566.0 24562.0 27371.0 True False 48715.147142639675 43503.84730522387 41670.98934675477 37336.00255742702 35561.90205358591 38003.15245163223 31767.162488285005 25842.727036804656 25860.297175683187 26412.749621084007 1.8443799998676682 1.6470775640297923 1.577684638841647 1.4135598562454668 1.3463915178750865 1.4388184871633423 1.2027207672058056 0.9784186579414538 0.97908387224631 1.0 14.688946876367432 -6.130141954369926 0.36462716757099395 0.9114014127914216 1.9938307757269682 0.9162074168580808 0.08267761069573983 0.7072276588022782 0.1505320790430239 0.0963644748135712 0.309446765403014 7.410679747369327e-07 6.130141954369926 1.0824293629355466 VTLYNTDQDGSDS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTLYNTDQDGSDSPR 15 0 C9JXI1;C9JVP0;Q9UPW0-2;Q9UPW0 C9JXI1 FOXJ3 Forkhead box protein J3 1 VTLYNT(0.003)DQDGS(0.227)DS(0.769)PR 108.96 0.0037153 0.0 6194.4 9924.8 6849.3 5948.4 10499.0 8938.1 7321.9 10046.0 8731.8 5292.3 True False 7242.989575023215 10910.06855328184 7012.613288114896 5615.130432972997 8441.796317702117 8469.370301374216 6628.316626034541 9782.303144616842 8859.486056057354 6251.752096176249 1.1585535484449607 1.7451217491420927 1.121703672863806 0.898169080697773 1.3503088714706653 1.3547194724106744 1.0602334392127624 1.5647298539876493 1.417120499943699 1.0 12.610044856232538 -7.7598416065599585 24.99998410605801 1.3681938235522737 1.2514020402300794 0.015374714188236549 0.25051241325855406 166.40178404744773 2603800.747803006 0.12661773913817986 0.06816393895110802 1.7384347452827486e-08 7.7598416065599585 -0.11679178332219431 VTLYNTDQDGSDS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 VTLYNTDQDGSDSPR 15 0 C9JXI1;C9JVP0;Q9UPW0-2;Q9UPW0 C9JXI1 FOXJ3 Forkhead box protein J3 1 VTLYNTDQDGS(0.344)DS(0.656)PR;VTLYNTDQDGS(0.104)DS(0.896)PR;VTLYNT(0.047)DQDGS(0.386)DS(0.567)PR 197.51 8.734700000000001e-10 24138900.0 76854.5 86119.6 102057.5 77270.0 92997.5 91098.3 95796.4 94158.7 101653.3 65700.6 True False 75758.54073661086 85920.19535737242 93666.72630334263 82952.69356516354 87527.56989011978 87202.23806950937 100756.26885661499 98533.65694523409 90204.03489729557 77056.86116945346 0.9831511378333007 1.1150232964774915 1.2155533573754438 1.0765127505355394 1.1358828865042983 1.1316609156677886 1.3075573975826094 1.2787136077156276 1.17061652302357 1.0 16.233635800072065 -7.02801820219193 22.609980408675767 1.213471093512201 1.112650130602923 0.12789224532557808 0.09472360143404877 356.36124574389174 287572.80222951947 0.03522840547192815 0.027380930985947547 9.375227125606895e-08 7.02801820219193 -0.100820962909278 VTNDISPES(ph)SPGVGR ddPTM_PC-9_AZD4547_30min_R2 1 VTNDISPESSPGVGR 15 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154;E9PGW9;E7EV93;E5RGQ4;Q15154-3 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 VT(0.062)NDIS(0.209)PES(0.684)S(0.046)PGVGR 165.24 0.00028577 34318000.0 30440.0 31886.0 39011.0 59495.0 50404.0 44994.0 33205.0 49718.0 32317.0 41672.0 True False 40119.28680866706 42192.52593528508 38493.68865066541 45779.34693858702 43406.27463637109 42180.51806721451 36160.180673391515 42035.22550598228 34025.210643536884 40213.075963969626 0.997667695070464 1.049224037800267 0.9572430789715076 1.138419428038897 1.079406973872442 1.0489254317428411 0.899214491967502 1.045312364158496 0.8461230539544653 1.0 15.295377074012467 -7.239751016708272 23.466699173671344 0.9514385134837491 1.0471342677446 0.33607460664244315 0.06700646716613742 433.11051150188814 468623.5584481499 0.024892638708942594 0.01925766845092849 5.757699346402398e-08 7.239751016708272 0.09569575426085097 VTNDISPES(ph)SPGVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTNDISPESSPGVGR 15 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154;E9PGW9;E7EV93;E5RGQ4;Q15154-3 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 VT(0.002)NDIS(0.08)PES(0.717)S(0.201)PGVGR 122.12 5.5157e-05 29596000.0 26022.0 24236.0 30389.0 34702.0 30154.0 30349.0 34938.0 31314.0 25765.0 21154.0 True False 30427.010642072524 26641.989909855976 31113.589010924297 32757.759445401975 24245.54016230019 28757.44501363892 31628.419710784736 30492.04067992555 26141.76438240886 24989.052745028148 1.2176136067473113 1.0661464514759047 1.2450887726072248 1.310884401247242 0.9702464679107979 1.1508017253419314 1.2656910221247808 1.220215947801074 1.046128664785425 1.0 14.609008594061232 -8.399067895983753 4.498388944448897 1.0028361158371024 1.1779389614907807 0.3108211508445444 0.0948135571467332 0.2751963716123985 8.18941209342163 0.09331804649528058 0.024428734268986174 3.989625251692897e-09 8.399067895983753 0.17510284565367829 VTNGAFTGEIS(ph)PGMIK ddPTM_PC-9_AZD4547_30min_R2 4 VTNGAFTGEISPGMIK 16 0 P60174;P60174-3 P60174 TPI1 Triosephosphate isomerase 1 VTNGAFT(0.014)GEIS(0.986)PGMIK;VTNGAFT(0.023)GEIS(0.977)PGMIK;VTNGAFT(0.403)GEIS(0.597)PGMIK;VTNGAFT(0.001)GEIS(0.999)PGMIK 119.62 0.00010574 41172500.0 199575.0 176264.0 226913.0 311866.0 301751.0 239883.0 198174.0 279878.0 222367.0 238632.0 True False 263035.69858211995 233237.8909696131 223903.98535767975 239970.11198166857 259858.08225140153 224883.07808858133 215811.10208609176 236629.28605662554 234120.8656487723 230277.56631392837 1.1422549872857946 1.0128554626621729 0.9723221803223343 1.0420907074140549 1.1284559169656465 0.9765739741317531 0.9371781434926447 1.0275828854906262 1.0166898556223427 1.0 17.81301434477689 VTNGAFTGEIS(ph)PGMIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VTNGAFTGEISPGMIK 16 0 P60174;P60174-3 P60174 TPI1 Triosephosphate isomerase 1 VTNGAFT(0.002)GEIS(0.998)PGMIK;VTNGAFT(0.065)GEIS(0.935)PGMIK;VTNGAFTGEIS(1)PGMIK;VTNGAFT(0.031)GEIS(0.969)PGMIK 122.5 5.0291000000000004e-05 31152500.0 165393.0 177388.0 180041.0 211914.0 240742.0 210208.0 218836.0 185498.0 178578.0 172017.0 True False 193390.7682393479 194997.90832354882 184333.86024929507 200041.14561445767 193570.3332809068 199184.32242996513 198106.2698445615 180628.8740513771 181189.3654136153 203202.32041417717 0.9517153536690385 0.9596244173102664 0.9071444650512679 0.9844432150515002 0.9525990298061657 0.980226613672411 0.9749212973590624 0.8889114734674793 0.8916697656026075 1.0 17.632557351108467 -10.424480191505696 4.367268990126522 1.0000008172317048 0.9447540414185968 0.2002591732267479 0.03380168931458971 9242321.619273372 5515436.820619845 69.6398003867854 0.00869041883589119 3.762875146297554e-11 10.424480191505696 -0.055246775813107996 VTNGAFTGEIS(ph)PGMIK ddPTM_PC-9_Lapatinib_30min_R1 2 VTNGAFTGEISPGMIK 16 0 P60174;P60174-3 P60174 TPI1 Triosephosphate isomerase 1 VTNGAFT(0.01)GEIS(0.99)PGMIK;VTNGAFT(0.004)GEIS(0.996)PGMIK 104.16 0.0012748 16501400.0 136224.0 107476.0 115636.0 109397.0 113469.0 112460.0 95952.0 97259.0 120211.0 93636.0 True False 134281.42077957783 107227.14592530561 106128.85444786826 117442.42031769402 106794.97650863713 107650.34795706418 100919.92506325823 101778.00820143546 106671.57130205106 109820.85783787246 1.2227314867437684 0.9763823378943558 0.9663815830372162 1.0693999539784438 0.9724471162508819 0.9802359048768988 0.9189504348276482 0.9267639153910945 0.9713234207251352 1.0 16.744792560123294 -4.761453841184742 8.680506758240037 0.9742370554330477 1.2248417312750601 0.7837728529165002 0.038909389493065785 0.04108979149087694 36.79250738170159 0.010500478880011556 0.06044337474058048 1.7319931051620564e-05 4.761453841184742 0.2506046758420124 VTNGAFTGEISPGMIK ddPTM_PC-9_Lapatinib_30min_R1 3 VTNGAFTGEISPGMIK 16 0 P60174;P60174-3 P60174 TPI1 Triosephosphate isomerase 0 ;; 205.3 2.8969e-16 15408300.0 73731.0 75094.0 81331.0 90290.0 81187.0 74367.0 83772.0 75112.0 74254.0 75328.0 False True 72679.58241939063 74920.12445676173 74644.27912673897 96930.22779861034 76411.74027978323 71186.49676794418 88109.30426045597 78601.9777298371 65890.73259071552 88348.34443174928 0.8226479272120027 0.8480082443948782 0.8448859976589945 1.0971368894579652 0.8648915921544258 0.8057479427125773 0.9972943446441379 0.8896825202034043 0.7458060817610149 1.0 16.430915479776438 VTNLLMLK ddPTM_PC-9_Lapatinib_30min_R1 1 VTNLLMLK 8 0 A6NLN1;P26599;P26599-2;P26599-3;K7ES59;K7ELW5;K7EKJ7;O95758-1;O95758-6;O95758-2;O95758;O95758-5;O95758-4;X6R242;A0A0U1RRM4 A6NLN1;O95758-1;A0A0U1RRM4 PTBP1;PTBP3 Polypyrimidine tract-binding protein 1;Polypyrimidine tract-binding protein 3 0 99.802 0.023441999999999998 1474600.0 10750.0 9261.9 11130.0 9115.8 10471.0 9075.7 11644.0 12245.0 8364.6 10073.0 False True 10596.70302869144 9240.454639599442 10214.934363042441 9786.206341417357 9855.116366778066 8687.553467490017 12246.869345470428 12813.947402570253 7422.490664857103 11814.104628571185 0.8969535450925679 0.7821544611389645 0.8646388942873151 0.8283493882177438 0.8341822488133794 0.7353543701043642 1.0366311904714849 1.084631278072572 0.6282736524024496 1.0 13.528222673535895 -7.26049474127805 24.999972993519933 0.9444366342769867 0.8242828980434445 0.17266125695322088 0.12161741523148573 149.0383899839895 3944381.593951064 0.047038165088441865 0.03432577497882441 5.4891520219148545e-08 7.26049474127805 -0.1201537362335422 VTPDHVQNTATLEITSPTTESPHSY(ph)TSTAVIPNCGTPK ddPTM_PC-9_AZD4547_30min_R2 1 VTPDHVQNTATLEITSPTTESPHSYTSTAVIPNCGTPK 38 0 C9JYJ6;Q4L180-6;Q4L180-5;Q4L180-3;Q4L180-7;Q4L180-2;Q4L180 C9JYJ6 FILIP1L Filamin A-interacting protein 1-like 1 VTPDHVQNTAT(0.001)LEIT(0.135)S(0.135)PT(0.046)T(0.046)ES(0.031)PHS(0.118)Y(0.198)T(0.097)S(0.097)T(0.097)AVIPNCGTPK 58.522 5.9263000000000005e-05 4822500.0 5111.9 2821.2 20768.0 35355.0 24861.0 28922.0 14277.0 29217.0 21204.0 23803.0 True False 6737.377865874675 3733.097728427091 20492.602750429865 27204.45097930489 21409.479282097076 27113.502767924114 15547.625341786195 24702.18398986854 22324.800151176034 22969.664215069333 0.29331634118772154 0.16252295608126385 0.89215943944821 1.1843643304745095 0.9320762846873185 1.1804048380531484 0.6768764748239601 1.075426430207133 0.9719254030944765 1.0 14.487442146200195 -5.31151117051815 4.884378802114994 0.9981462549025003 0.22434315405297756 0.8265267913957575 0.13991231562413564 0.06754972403543484 3.6434722671816218 0.03554908339445286 0.0798958844026661 4.880775472100641e-06 5.31151117051815 -0.7738031008495228 down VTPFNYNPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 VTPFNYNPSPR 11 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 VTPFNY(0.032)NPS(0.968)PR 69.846 0.033698 3640500.0 10410.0 11157.0 10840.0 10494.0 13235.0 10461.0 8396.2 8673.4 12362.0 6535.9 True False 10261.55149103981 11131.16665198404 9948.777043610069 11265.763766957782 12456.54332101115 10013.60741578204 8830.914153077882 9076.39782780341 10969.661382368962 7665.621606460676 1.3386457117047434 1.4520892399127243 1.2978434828070724 1.4696477787871585 1.6249880258259328 1.3063007711393495 1.1520154015474862 1.184039376552805 1.431020463249008 1.0 12.904187069657276 -6.994906712596362 24.970680352315526 1.2102557867154138 1.4350256202902252 0.4484409066221474 0.12755680420622587 137.22518671360393 672763.4444662274 0.04477534447946239 0.039358224152594434 1.0117967670757542e-07 6.994906712596362 0.2247698335748114 VTPLPSLAS(ph)PAVPAPGYCSR ddPTM_PC-9_AZD4547_30min_R2 1 VTPLPSLASPAVPAPGYCSR 20 0 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3;H7C3V8 C9JWC4 HJURP Holliday junction recognition protein 1 VTPLPS(0.009)LAS(0.991)PAVPAPGYCSR 80.541 0.0014135 12128000.0 25053.0 27711.0 29714.0 51937.0 52440.0 34086.0 32223.0 47141.0 41308.0 40622.0 True False 33019.33286522788 36668.0388318599 29319.972945217312 39963.727068651075 45159.611180289256 31954.597031583617 35090.78457577761 39856.44164241339 43491.45654804661 39199.836144374516 0.8423334409770591 0.9354130638916471 0.7479616199728671 1.0194870948302721 1.1520357129546321 0.8151716990319449 0.8951768177432398 1.0167502102718127 1.1094805699663104 1.0 15.258560003425842 -4.401945216700786 0.31341216078687123 1.023647177479521 0.6552737936301561 0.2091722238162237 0.10954129975141194 17.475463352797405 1.1614230623338695 0.12518510436547442 2.5695183509661255 3.963280251909284e-05 4.401945216700786 -0.3683733838493649 VTPLPSLAS(ph)PAVPAPGYCSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTPLPSLASPAVPAPGYCSR 20 0 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3;H7C3V8 C9JWC4 HJURP Holliday junction recognition protein 1 VTPLPS(0.029)LAS(0.971)PAVPAPGYCSR 108.47 9.895e-05 6633600.0 15904.0 15366.0 16732.0 16827.0 18036.0 15687.0 16002.0 14054.0 14224.0 9688.8 True False 18596.233081681723 16891.434929643794 17130.954336463354 15884.237743870064 14501.975272509319 14864.346104614777 14486.174715552626 13685.097391443871 14431.999090835761 11445.302743501401 1.6247917157316432 1.4758399413449055 1.4967672520668136 1.3878390200634119 1.2670678615944417 1.298728957873543 1.2656873339394907 1.1956955353770975 1.260953896482135 1.0 13.482468004153102 -1.5228787452809376 0.13139125325997023 0.9325566836970545 3.1965517409502033 0.9274958590677301 0.04505976141527953 20.044724231822862 0.1785173481706395 0.23574584574881988 8.418607054213586 0.029999999999958553 1.5228787452809376 2.263995057253149 VTPLPSLAS(ph)PAVPAPGYCSR ddPTM_PC-9_Lapatinib_30min_R1 1 VTPLPSLASPAVPAPGYCSR 20 0 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3;H7C3V8 C9JWC4 HJURP Holliday junction recognition protein 1 VTPLPS(0.004)LAS(0.995)PAVPAPGY(0.001)CSR 99.01100000000001 0.0003773 6328000.0 27561.0 19838.0 24313.0 20966.0 23038.0 22700.0 12676.0 18485.0 23748.0 16636.0 True False 27167.97508593162 19792.066329843095 22314.078990894053 22507.909580525713 21682.950134450686 21729.173916284522 13332.301255855646 19343.880582810216 21073.250162473556 19511.510433923377 1.3924075831000993 1.0143789942285522 1.1436366787933565 1.153570845104472 1.1112901898538807 1.1136592418035172 0.6833044166932178 0.9914086686583877 1.0800419697818415 1.0 14.252037844384349 -7.0286802541410225 24.710436493598113 0.9323312150676705 1.149119486172548 0.39830208996215266 0.13066256275425056 644.0261139275719 554880.2749743247 0.04886578933379559 0.03793265805761668 9.360946127188501e-08 7.0286802541410225 0.21678827110487753 VTPPEGYEVVTVFPK ddPTM_PC-9_Lapatinib_30min_R1 2 VTPPEGYEVVTVFPK 15 0 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 0 ; 168.98 0.00074523 7400300.0 56832.0 41339.0 53997.0 49458.0 47001.0 52691.0 46320.0 43131.0 51051.0 43548.0 False True 56021.5652582876 41243.282085360566 49557.57509444767 53095.30630705143 44236.49358752133 50437.52875872019 48718.22295449937 45135.02371745673 45301.098789137555 51075.213775937475 1.0968444597030829 0.8075009194536368 0.9702862001097528 1.0395513279685118 0.8661049130715924 0.9875147851555794 0.9538525510284104 0.8836972061528741 0.8869487847445835 1.0 15.640335716938484 -7.676417325430855 10.708627730941632 0.9140377501433752 0.9553002885465797 0.034262981534972314 0.08200050020499826 1.3473622204903832 159.6456756705623 0.03689891170572326 0.02127534626615561 2.1066028847668517e-08 7.676417325430855 0.041262538403204485 VTPTEEHVEGPLPS(ph)PVTNGTSPAQLNGGSACSSR ddPTM_PC-9_AZD4547_30min_R2 3 VTPTEEHVEGPLPSPVTNGTSPAQLNGGSACSSR 34 0 H3BN50;Q15599-3;H3BQS0;Q15599;H3BUQ9;Q15599-2 H3BN50;Q15599-2 SLC9A3R2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 1 VTPTEEHVEGPLPS(0.918)PVT(0.077)NGT(0.003)S(0.001)PAQLNGGSACSSR;VTPTEEHVEGPLPS(0.94)PVT(0.031)NGT(0.026)S(0.002)PAQLNGGSACSSR;VTPTEEHVEGPLPS(0.462)PVT(0.381)NGT(0.138)S(0.018)PAQLNGGS(0.001)ACSSR 107.98 2.7507e-21 76549000.0 108949.1 99091.0 159045.0 212036.0 180807.0 155465.0 132582.0 193542.0 162777.0 165770.0 True False 143592.64751794186 131120.2279198813 156935.959381843 163154.37612354374 155705.0690059982 145743.74897363025 144381.54115463296 163634.5310527135 171381.05990416827 159966.44275646086 0.8976423119976038 0.8196733368604303 0.981055505627317 1.0199287632590313 0.973360826951998 0.9110895164151159 0.9025739315491627 1.022930361099778 1.0713563229325882 1.0 17.287409767384247 -2.0044360239955847 0.31202532435780506 1.0053431890119005 1.4817991184988595e-13 0.355698433887115 0.05757196802709744 51.23233056805168 0.9669359302972035 0.06225629081856897 27.60887546538687 0.00989837666308474 2.0044360239955847 -1.0053431890117523 VTPTEEHVEGPLPS(ph)PVTNGTSPAQLNGGSACSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VTPTEEHVEGPLPSPVTNGTSPAQLNGGSACSSR 34 0 H3BN50;Q15599-3;H3BQS0;Q15599;H3BUQ9;Q15599-2 H3BN50;Q15599-2 SLC9A3R2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 1 VTPTEEHVEGPLPS(0.908)PVT(0.092)NGTSPAQLNGGSACSSR;VTPTEEHVEGPLPS(0.956)PVT(0.043)NGTSPAQLNGGSACSSR;VTPTEEHVEGPLPS(0.926)PVT(0.071)NGT(0.002)S(0.001)PAQLNGGSACSSR;VTPTEEHVEGPLPS(0.955)PVT(0.045)NGTSPAQLNGGSACSSR 135.47 2.0083e-24 65848700.0 97034.9 86608.8 108539.0 120442.0 161809.0 146073.0 136656.0 149246.0 130773.0 118151.0 True False 113460.9920433652 95206.749286381 111126.98139644983 113694.02521823256 130103.68800562553 138412.67473318 123710.95437623779 145328.45063920837 132685.30772679052 139570.84101719857 0.8129276231084973 0.6821392533892461 0.7962048561615835 0.8145972639386951 0.9321695495808723 0.991701946656065 0.8863667616718992 1.0412522385051783 0.95066639105829 1.0 17.09063804124277 -6.1684634081671215 1.6199048128955151 0.9740135699781164 0.7499124524082375 0.7917576391144158 0.04881200063347429 0.15750569110949827 0.8218644851868403 0.016570588142189962 0.024165359019697186 6.784792839109473e-07 6.1684634081671215 -0.22410111756987894 VTPTEEHVEGPLPS(ph)PVTNGTSPAQLNGGSACSSR ddPTM_PC-9_Lapatinib_30min_R1 3 VTPTEEHVEGPLPSPVTNGTSPAQLNGGSACSSR 34 0 H3BN50;Q15599-3;H3BQS0;Q15599;H3BUQ9;Q15599-2 H3BN50;Q15599-2 SLC9A3R2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 1 VTPTEEHVEGPLPS(0.998)PVT(0.002)NGTSPAQLNGGSACSSR;VTPTEEHVEGPLPS(0.77)PVT(0.225)NGT(0.004)S(0.002)PAQLNGGSACSSR;VTPTEEHVEGPLPS(0.998)PVT(0.001)NGTSPAQLNGGSACSSR 137.21 1.3105e-24 58328000.0 137784.0 131250.0 141752.0 136930.0 169713.0 175564.0 134741.0 124272.0 193109.0 137351.0 True False 135819.17489350916 130946.09868897613 130097.69773854401 147000.28898508946 159730.8150085957 168055.53697967302 141717.22968722353 130046.13079724023 171359.03089207955 161091.93734129658 0.8431159071962527 0.8128656272321554 0.8075990635267687 0.9125241859476063 0.9915506489327449 1.0432274870692197 0.8797288804527509 0.8072789547605892 1.0637343725591346 1.0 17.297524763336583 -5.891543741602476 4.02764037540972 0.9542662882309195 0.8205997831231361 0.43825014640338145 0.07174220262205123 0.23206285836139057 6.923879890472596 0.021633370808380955 0.03332038467067679 1.2836784734548654e-06 5.891543741602476 -0.13366650510778344 VTPTEEHVEGPLPSPVT(ph)NGTSPAQLNGGSACSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTPTEEHVEGPLPSPVTNGTSPAQLNGGSACSSR 34 0 H3BN50;Q15599-3;H3BQS0;Q15599;H3BUQ9;Q15599-2 H3BN50;Q15599-2 SLC9A3R2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 1 VTPTEEHVEGPLPS(0.008)PVT(0.429)NGT(0.151)S(0.391)PAQLNGGS(0.02)ACSSR 134.13 2.0452e-21 25087000.0 11520.0 9497.6 15257.0 12452.0 16659.0 16595.0 14340.0 10506.0 10877.0 8075.2 True False 13470.108469628598 10440.458960548283 15620.784742494703 11754.35480992868 13394.78853763211 15724.728986172131 12981.611387390612 10230.228632027132 11036.055547737678 9539.169836751973 1.4120839339427345 1.0944829727555405 1.6375413175171523 1.2322198903139525 1.4041880757825935 1.6484378887551394 1.3608743328351065 1.07244433290334 1.1569199140598785 1.0 13.219648003249862 -7.72871517652162 5.527596480335678 1.0843464848235222 1.4014182871907697 0.4635260144740093 0.1590457241739408 0.1652717643486823 13.238991840968023 0.07959733545698089 0.043171179578076986 1.8676041206439324e-08 7.72871517652162 0.3170718023672474 VTPTEEHVEGPLPSPVTNGT(ph)SPAQLNGGSACSSR ddPTM_PC-9_AZD4547_30min_R2 1 VTPTEEHVEGPLPSPVTNGTSPAQLNGGSACSSR 34 0 H3BN50;Q15599-3;H3BQS0;Q15599;H3BUQ9;Q15599-2 H3BN50;Q15599-2 SLC9A3R2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 1 VTPTEEHVEGPLPSPVT(0.036)NGT(0.953)S(0.01)PAQLNGGS(0.001)ACSSR 146.45 4.7851999999999995e-22 42387000.0 31213.0 31538.0 43968.0 65218.0 54755.0 48375.0 41792.0 58114.0 37551.0 46590.0 True False 41138.08472926827 41732.041740795976 43384.95559181914 50182.99770805561 47153.21339009795 45350.10360273595 45511.407038168334 49133.816626868575 39535.86919811411 44958.89828089231 0.915015409680359 0.9282265210340406 0.9649915200492779 1.116197229623475 1.048807137032053 1.0087013992068818 1.012289196986636 1.0928607796368226 0.8793780699674527 1.0 15.456319062257585 -5.532072773785515 24.71535585747065 1.0276364990288365 0.9278679584062501 0.31686831278535166 0.06004093422432182 180.55771288818337 485372.73730679223 0.015854310267623194 0.027512232511322943 2.9371574376140156e-06 5.532072773785515 -0.09976854062258633 VTQDFTHPPDQS(ph)PLRPDAANR ddPTM_PC-9_AZD4547_30min_R2 1 VTQDFTHPPDQSPLRPDAANR 21 1 Q9BYX2-4;Q9BYX2-2;Q9BYX2;Q9BYX2-3 Q9BYX2-4 TBC1D2 TBC1 domain family member 2A 1 VTQDFT(0.001)HPPDQS(0.998)PLRPDAANR 45.678999999999995 0.034033 6198200.0 6064.3 8428.4 10223.0 9951.8 9813.3 6578.5 7162.9 8180.8 9930.8 10076.0 True False 7992.621254724037 11152.715473654791 10087.436340410459 7657.566263777297 8450.89268488811 6167.1453550511305 7800.384223624037 6916.645336082294 10455.721813869977 9723.242306895712 0.8220119382457104 1.1470161003542303 1.0374560277343352 0.7875527547376413 0.8691434830226071 0.6342684014649514 0.8022410608950898 0.7113517402705286 1.0753328451410484 1.0 13.247221758996007 -5.759562273900637 24.99963531360978 0.819028137210582 1.0166468685986139 0.20223534168866608 0.14257253390967703 62.52962123465369 832753.1937874784 0.03805166630722718 0.06185217268362564 1.7395532439525577e-06 5.759562273900637 0.19761873138803188 VTQDFTHPPDQS(ph)PLRPDAANR ddPTM_PC-9_Lapatinib_30min_R1 1 VTQDFTHPPDQSPLRPDAANR 21 1 Q9BYX2-4;Q9BYX2-2;Q9BYX2;Q9BYX2-3 Q9BYX2-4 TBC1D2 TBC1 domain family member 2A 1 VTQDFTHPPDQS(1)PLRPDAANR 44.089 0.034858999999999994 6650000.0 5798.4 5347.9 6566.3 9132.9 6893.7 5877.3 6123.4 7348.4 7546.4 7110.9 True False 5715.71375270367 5335.517266123994 6026.444160650996 9804.563932461277 6488.226119535664 5625.941579655467 6440.439689973688 7689.833490653104 6696.444964885064 8340.009590321333 0.6853365923387924 0.6397495360575983 0.7225943921748899 1.1756058342953914 0.7779638679391109 0.6745725551903957 0.7722340868106295 0.9220413246979038 0.8029301276411429 1.0 13.02583332731297 -1.522878754353352 0.060617274683400654 1.2039189289709802 7.44880790180874e-07 0.19392802650802998 0.14331239972424817 663.9216852023537 3.0162851992464343 12.045184873196117 70.44627569987834 0.029999999373258375 1.522878754353352 -1.20391818409019 VTQGAAS(ph)PGHGIQEK ddPTM_PC-9_AZD4547_30min_R2 1 VTQGAASPGHGIQEK 15 0 G5E9C0;Q9HB58-2;Q9HB58-5;Q9HB58-3;Q9HB58-7;Q9HB58;Q9HB58-6;Q9HB58-4 G5E9C0 SP110 Sp110 nuclear body protein 1 VTQGAAS(1)PGHGIQEK 102.72 0.0014254 8245200.0 39343.0 40454.0 47116.0 56123.0 56670.0 55438.0 46616.0 60371.0 44606.0 52907.0 True False 51853.25561476308 53529.964378913086 46491.21105495247 43184.70944170636 48802.34869540414 51971.4530961959 50764.73369284203 51042.04913756897 46963.78209504617 51054.74203363747 1.015640341118549 1.0484817324832396 0.9106149439423608 0.8458510947573503 0.9558827789835987 1.0179554538137605 0.9943196590709563 0.9997513865399587 0.9198711074498042 1.0 15.639757346346702 -6.561043824911931 22.01218200194078 0.9868669247794422 0.9514121977857941 0.06825690604283308 0.056748813061712 143.43583149028018 82725.7459855398 0.02083453351007793 0.020834665719594088 2.747616875475491e-07 6.561043824911931 -0.035454726993648045 VTQGAAS(ph)PGHGIQEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTQGAASPGHGIQEK 15 0 G5E9C0;Q9HB58-2;Q9HB58-5;Q9HB58-3;Q9HB58-7;Q9HB58;Q9HB58-6;Q9HB58-4 G5E9C0 SP110 Sp110 nuclear body protein 1 VT(0.096)QGAAS(0.904)PGHGIQEK 75.998 0.0081593 8478800.0 45446.0 44573.0 44826.0 49097.0 53031.0 46662.0 53693.0 46962.0 44100.0 37619.0 True False 53139.11020058523 48997.91286730532 45894.821843551705 46346.25426462161 42639.956236218764 44214.96257624367 48606.81033634336 45729.297260351996 44744.879070996714 44439.026908159874 1.1957757380782756 1.1025874389321595 1.0327593792366438 1.0429178469727367 0.9595159750986635 0.9949579379319158 1.0937865592060974 1.0290346220869926 1.0068825126047185 1.0 15.43953960558918 -4.825890091488394 1.4803496235966795 1.0189698266464353 1.2571992844553588 0.7426943349794568 0.03292136500004707 0.5692013528866253 1.2379719053378115 0.010163471496990706 0.19662380439704433 1.4931722443922009e-05 4.825890091488394 0.23822945780892346 VTQGAAS(ph)PGHGIQEK ddPTM_PC-9_Lapatinib_30min_R1 2 VTQGAASPGHGIQEK 15 0 G5E9C0;Q9HB58-2;Q9HB58-5;Q9HB58-3;Q9HB58-7;Q9HB58;Q9HB58-6;Q9HB58-4 G5E9C0 SP110 Sp110 nuclear body protein 1 VTQGAAS(1)PGHGIQEK;VT(0.006)QGAAS(0.994)PGHGIQEK 145.82 1.5200999999999999e-05 19983500.0 61914.0 54582.0 67250.0 62217.0 60109.0 61348.0 53254.0 50076.0 60383.0 45987.0 True False 61031.09500636299 54455.61873250808 61720.96459250713 66792.64572982762 56573.506798840885 58724.28904917286 56011.23154617677 52402.71377142571 53582.030678821015 53935.79167617426 1.1315509258265515 1.0096378868313423 1.144341497072563 1.238373326025226 1.0489047261696507 1.0887814422331707 1.0384798258355652 0.9715758709179052 0.9934410715712269 1.0 15.718955339670158 -7.274985308331221 1.4646194270880377 0.985421595225519 1.1179839756002214 0.4930263303572753 0.056705785740808715 0.38224510553984675 1.5976877451862903 0.035911814111382036 0.021015151006149334 5.309024037277499e-08 7.274985308331221 0.13256238037470247 VTQHES(ph)DNENEIQIQNK ddPTM_PC-9_AZD4547_30min_R2 6 VTQHESDNENEIQIQNK 17 0 Q5VZL5-2;Q5VZL5-4;Q5VZL5 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 VT(0.039)QHES(0.961)DNENEIQIQNK;VT(0.321)QHES(0.679)DNENEIQIQNK;VT(0.098)QHES(0.902)DNENEIQIQNK;VT(0.03)QHES(0.97)DNENEIQIQNK;VT(0.009)QHES(0.991)DNENEIQIQNK;VT(0.007)QHES(0.993)DNENEIQIQNK 223.82 4.0375999999999997e-29 118086500.0 262795.6 261220.6 352210.0 446329.0 393135.0 379388.0 324569.0 384345.0 299077.6 339117.0 True False 346359.13431195 345655.05050275096 347539.46527007385 343434.7447643103 338554.9912540627 355664.80838521605 353455.01222653256 324953.3116194692 314886.2313569782 327244.6170491815 1.0584104864279427 1.0562589344313114 1.0620173630475402 1.0494740841304522 1.0345624453867834 1.086846933013915 1.0800941980763337 0.9929981875626455 0.962235022217811 1.0 18.320009935452788 -7.841278905646391 5.77241987015456 0.9807497133880585 1.0603714659801993 0.8199410524791874 0.016344764241606934 0.08416895885988666 4.588682395965021 0.009474009813958227 0.0044914133117376865 1.4411895166203715e-08 7.841278905646391 0.07962175259214077 VTQHES(ph)DNENEIQIQNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VTQHESDNENEIQIQNK 17 0 Q5VZL5-2;Q5VZL5-4;Q5VZL5 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 VT(0.122)QHES(0.878)DNENEIQIQNK;VT(0.01)QHES(0.99)DNENEIQIQNK;VT(0.288)QHES(0.712)DNENEIQIQNK;VT(0.001)QHES(0.999)DNENEIQIQNK 178.84 1.7452e-06 66034000.0 285630.0 321536.0 336186.0 370504.0 383509.0 307450.0 358912.0 298431.0 307649.0 260122.0 True False 333981.5175503482 353455.9691226057 344201.94923250563 349745.8620701751 308363.16449239105 291326.78076520737 324913.2570621436 290597.5024637819 312147.78461027436 307280.05947538145 1.086896162805208 1.1502730431843193 1.1201571290377932 1.1381990184045636 1.0035248138745443 0.9480822844885832 1.0573847766655189 0.9457089501997571 1.0158413310099053 1.0 18.229194622658305 -6.286937673250268 6.778750451122829 0.9927497016867305 1.1256043783876417 0.7778353622649369 0.033709161447612004 0.07994363483525123 14.813356584875201 0.009785862612881646 0.011376129499614834 5.164904868693365e-07 6.286937673250268 0.13285467670091122 VTQHES(ph)DNENEIQIQNK ddPTM_PC-9_Lapatinib_30min_R1 3 VTQHESDNENEIQIQNK 17 0 Q5VZL5-2;Q5VZL5-4;Q5VZL5 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 VT(0.311)QHES(0.689)DNENEIQIQNK;VT(0.03)QHES(0.97)DNENEIQIQNK;VT(0.022)QHES(0.978)DNENEIQIQNK 223.44 4.2131000000000003e-29 133830000.0 352308.0 336497.0 373682.0 311165.0 326505.0 342927.0 308371.0 316041.0 373418.0 261646.0 True False 347284.02331462625 335717.8618708135 342959.30841423344 334049.1121160112 307300.61783352797 328260.8116118811 324336.941509109 330725.4186243937 331359.73257413483 306871.1624786193 1.1316932503842638 1.094002639932659 1.1176003168369675 1.0885646908555164 1.00139946468557 1.0697023759433637 1.0569156739571661 1.0777337823244841 1.0798008190072983 1.0 18.227273552617113 -1.5228787452803376 0.27945427894331587 1.0416074119855039 1.723432029833454 0.4674398681573376 0.029996439927251362 53.01357809495697 0.7469082084767302 0.03509822868983252 17.63728559196332 0.029999999999999995 1.5228787452803376 0.6818246178479501 VTQQEKT(ph)PPPRPSPLEAGSDGCEEPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTQQEKTPPPRPSPLEAGSDGCEEPK 26 2 Q9BUA3 Q9BUA3 C11orf84 Uncharacterized protein C11orf84 1 VT(0.081)QQEKT(0.9)PPPRPS(0.004)PLEAGS(0.014)DGCEEPK 40.668 0.041513999999999995 10224000.0 34981.0 28878.0 24377.0 38645.0 37759.0 25311.0 33513.0 41219.0 36685.0 30727.0 True False 40902.59239375677 31744.816991946755 24958.240130287326 36479.845938780454 30360.395005249466 23983.646602531066 30338.40602689133 40137.044925140515 37221.44872379853 36297.56186520184 1.1268688664449866 0.8745716064852345 0.6876010081055768 1.0050219371277764 0.836430697962546 0.6607508981346756 0.8358249002938266 1.1057779879044591 1.025453138203269 1.0 15.147585024103375 -7.754131967178676 24.81728086893534 1.0492116818547141 0.8517532796391626 0.2902276889525617 0.13030846113374955 182.24741017831832 618951.234227952 0.06453473112437864 0.03627953145569152 1.7614407237374375e-08 7.754131967178676 -0.19745840221555155 VTQQEKT(ph)PPPRPSPLEAGSDGCEEPK ddPTM_PC-9_Lapatinib_30min_R1 2 VTQQEKTPPPRPSPLEAGSDGCEEPK 26 2 Q9BUA3 Q9BUA3 C11orf84 Uncharacterized protein C11orf84 1 VT(0.09)QQEKT(0.899)PPPRPS(0.007)PLEAGS(0.003)DGCEEPK;VT(0.025)QQEKT(0.954)PPPRPS(0.009)PLEAGS(0.012)DGCEEPK 54.656000000000006 0.0024633000000000003 38061000.0 70265.0 102330.0 103448.0 113952.0 122011.0 114654.0 118275.0 107450.0 109657.0 110437.0 True False 69263.008214977 102093.06117213669 94942.9047608278 122332.41021272843 114834.55286285529 109750.51569152791 124398.7007759803 112442.51926551037 97306.27392059815 129525.8883019473 0.5347425840733315 0.7882058367678596 0.7330033092650902 0.9444630090283602 0.8865760688330971 0.8473249412170054 0.960415731610235 0.8681084587768846 0.7512496165535677 1.0 16.982880952210635 -4.287158125427477 0.9299017472217044 0.886622353152684 1.853873986010514e-15 0.6571723157838802 0.07599909407806514 2.858344281206575 1.0338588791875767 0.024779610198177524 3.187684298837298 5.1622837771674416e-05 4.287158125427477 -0.8866223531526821 VTQVDGNS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 2 VTQVDGNSPVR 11 0 B0YIW6;P48444;P48444-2 B0YIW6 ARCN1 Coatomer subunit delta 1 VT(0.002)QVDGNS(0.998)PVR;VT(0.002)QVDGNS(0.998)PVR 90.759 0.01305 11356000.0 31384.0 27367.0 46183.0 62072.0 45156.0 46312.0 38341.0 51431.0 40273.0 45303.0 True False 41363.459172247305 36212.847559146525 45570.583244563866 47762.25940284012 38886.86884929715 43416.10331886116 41753.27472364115 43483.52071680628 42401.748561041 43716.95575916003 0.9461651309876581 0.8283478785358661 1.0424006533212333 1.0925339739108544 0.8895145641779773 0.9931181749718281 0.9550819355689599 0.9946603088366957 0.9699153983785009 1.0 15.415905321637139 -5.263831284753553 24.99022741150336 0.9905922848662241 0.8872565057839826 0.3544155182000439 0.056597996788261724 216.8423119729925 2265561.6147648003 0.014841381226322564 0.03347227841642642 5.447142229854762e-06 5.263831284753553 -0.10333577908224145 VTQVDGNS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 1 VTQVDGNSPVR 11 0 B0YIW6;P48444;P48444-2 B0YIW6 ARCN1 Coatomer subunit delta 1 VTQVDGNS(1)PVR 93.228 0.019268 0.0 24589.0 20985.0 29890.0 24717.0 21614.0 24107.0 29078.0 23274.0 30117.0 21350.0 True False 24238.356350929662 20936.410521814556 27432.559578736626 26534.770633494896 20342.707014758977 23075.999806161715 30583.5165602533 24355.395005914263 26724.906313930303 25040.319052913226 0.9679731436213365 0.8361079776009797 1.0955355449252986 1.0596818106599886 0.8123980757502479 0.9215537452777393 1.2213708817218594 0.9726471517574662 1.0672749918823854 1.0 14.611965324133209 VTRS(ph)PPETAAPVEDMAR ddPTM_PC-9_AZD4547_30min_R2 1 VTRSPPETAAPVEDMAR 17 1 Q9Y3L3;A0A2R8Y5V0;Q6ZT62-2;Q6ZT62;A0A3B3IU28 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 VT(0.012)RS(0.987)PPET(0.001)AAPVEDMAR 129.42 6.5672e-05 29613000.0 15548.0 10373.0 14904.0 27901.0 21379.0 16341.0 13710.0 15781.0 13333.0 18756.0 True False 20491.940581509716 13725.869394929192 14706.363221899403 21468.855516152904 18410.89487840206 15319.194686766072 14930.163440210743 13342.409061303879 14037.755160141025 18099.35814888208 1.1321915624270587 0.7583622182633577 0.8125350689746836 1.1861666772685497 1.0172125843887578 0.8463943616537736 0.8249001604033631 0.7371758131725784 0.7755940870758491 1.0 14.143650915982585 -6.875804382525927 5.344426694267753 0.8158221861709212 0.9704119809764988 0.2115632335495954 0.13667837900374508 0.34519294813820217 14.810375691381482 0.05075910272219635 0.04478761474799495 1.3310538240636219e-07 6.875804382525927 0.15458979480557766 VTRS(ph)PPETAAPVEDMAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTRSPPETAAPVEDMAR 17 1 Q9Y3L3;A0A2R8Y5V0;Q6ZT62-2;Q6ZT62;A0A3B3IU28 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 VT(0.002)RS(0.983)PPET(0.014)AAPVEDMAR 92.096 0.0045674 25968000.0 76175.0 79456.0 68835.0 118000.0 97367.0 97981.0 100830.0 103340.0 82254.0 79346.0 True False 89069.92297516986 87343.86657358946 70476.28745819115 111388.84256116174 78288.63530485774 92842.7038743075 91278.65245401638 100627.43449778047 83456.80914072019 93730.80169740946 0.950273777266023 0.9318587379158572 0.7519010419403995 1.1883910149489345 0.8352498206256299 0.9905250162484579 0.9738383839785203 1.073579150881856 0.8903882995703297 1.0 16.516235601967672 -5.7346631169618805 24.99995806265578 0.9887130458545084 0.883396127892594 0.20858697848699825 0.10235064777999371 372.8987873788115 348158.32854160375 0.026438104210197138 0.04577630408565726 1.842200445689175e-06 5.7346631169618805 -0.10531691796191434 VTRS(ph)PPETAAPVEDMAR ddPTM_PC-9_Lapatinib_30min_R1 3 VTRSPPETAAPVEDMAR 17 1 Q9Y3L3;A0A2R8Y5V0;Q6ZT62-2;Q6ZT62;A0A3B3IU28 Q9Y3L3 SH3BP1 SH3 domain-binding protein 1 1 VT(0.169)RS(0.831)PPETAAPVEDMAR;VT(0.196)RS(0.804)PPETAAPVEDMAR;VT(0.005)RS(0.989)PPET(0.006)AAPVEDMAR 113.52 8.9025e-05 78886000.0 49219.0 40232.0 49762.0 33932.0 45567.0 39509.0 39933.0 36386.0 46913.0 34047.0 True False 48517.128034340865 40138.8452758467 45670.76044687489 36427.47247383373 42886.838648168894 37819.292169977314 42000.53534633037 38076.626393623636 41629.163924209286 39931.97858522416 1.2149943417102158 1.0051804768496768 1.1437139371745086 0.9122381050087214 1.073997336661853 0.9470928691715618 1.0518020101781689 0.9535371835472471 1.042501909474957 1.0 15.285256937229681 -1.5228840488132218 0.9478812575965538 1.0049049378222445 137.56119241030004 0.4485716543077727 0.06542404715376608 1024.4823326738417 1.79411738333311 0.019031412948647165 303311.09141209914 0.02999963364716414 1.5228840488132218 136.5562874724778 VTRS(ph)PPTQVAISSDSAR ddPTM_PC-9_AZD4547_30min_R2 4 VTRSPPTQVAISSDSAR 17 1 Q6ZUT6;Q6ZUT6-4;H0YM82;Q6ZUT6-3 Q6ZUT6 C15orf52 Uncharacterized protein C15orf52 1 VTRS(0.93)PPT(0.07)QVAISSDSAR;VT(0.367)RS(0.628)PPT(0.004)QVAISS(0.001)DSAR;VT(0.238)RS(0.746)PPT(0.015)QVAISSDSAR;VT(0.06)RS(0.9)PPT(0.006)QVAIS(0.017)S(0.017)DSAR 167.95 9.667100000000001e-05 135059000.0 38379.2 26247.5 41012.4 69107.0 51964.9 43945.4 35274.2 50119.4 35685.0 43518.4 True False 50582.98726304849 34731.491077162216 40468.54877897387 53175.44884250668 44750.47061446632 41197.487190980304 38413.53546481996 42374.59835923666 37571.236247628614 41994.83406197007 1.20450499193318 0.8270419886862839 0.9636554038826795 1.2662378606863367 1.06561846508144 0.9810132153442218 0.9147204965290413 1.0090431193681153 0.8946632862553111 1.0 15.357924247165583 -6.860335786233156 4.615304794120193 0.9547362071456857 1.0574583745638475 0.16899808717135323 0.11725814665531854 0.45836306957904793 16.810390898911425 0.04398867137846111 0.03891603250847083 1.3793173965929318e-07 6.860335786233156 0.10272216741816176 VTRS(ph)PPTQVAISSDSAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VTRSPPTQVAISSDSAR 17 1 Q6ZUT6;Q6ZUT6-4;H0YM82;Q6ZUT6-3 Q6ZUT6 C15orf52 Uncharacterized protein C15orf52 1 VT(0.3)RS(0.695)PPT(0.005)QVAISSDSAR;VT(0.054)RS(0.946)PPT(0.001)QVAISSDSAR;VT(0.002)RS(0.997)PPT(0.001)QVAISSDSAR 214.63 1.3825999999999999e-21 38531000.0 27060.799999999996 25387.7 41001.0 37847.0 51820.0 40851.0 36441.0 40169.4 36921.8 25514.3 True False 31641.658964837305 27908.023074535857 41978.6193371584 35726.55529162952 41666.24299298256 38708.70164592454 32989.04467000704 39114.99581299741 37461.711475816934 30139.84061891232 1.049828343982105 0.9259512492917421 1.3927950007412255 1.185359794809652 1.382430767296015 1.2843034618316922 1.0945328174465159 1.2977837642729042 1.2429299792750146 1.0 14.879384167456893 -5.249551745454796 24.995604242355164 1.2458863359290766 0.9878897736147626 0.4102525485773775 0.11794436531194712 654.2709046751661 1375700.6471904076 0.028335512995966452 0.07364017430220633 5.6292204218678485e-06 5.249551745454796 -0.257996562314314 VTRS(ph)PPTQVAISSDSAR ddPTM_PC-9_Lapatinib_30min_R1 2 VTRSPPTQVAISSDSAR 17 1 Q6ZUT6;Q6ZUT6-4;H0YM82;Q6ZUT6-3 Q6ZUT6 C15orf52 Uncharacterized protein C15orf52 1 VT(0.203)RS(0.77)PPT(0.026)QVAIS(0.001)S(0.001)DSAR;VT(0.02)RS(0.963)PPT(0.015)QVAIS(0.001)S(0.001)DSAR 157.47 0.00013501 66229000.0 55831.0 40169.0 45401.0 40956.0 41012.0 37986.0 30241.4 27465.7 42521.0 35106.9 True False 55034.83970184856 40075.99114847598 41668.30503292809 43968.04086521089 38599.7547926943 36361.42732969092 31807.15171969337 28741.856690467437 37731.837214019644 41175.08088799622 1.3366055030117228 0.9733069197238503 1.0119787049422813 1.0678313173157337 0.9374542553466433 0.8830930394186882 0.7724854701855878 0.6980400783826161 0.9163755456038367 1.0 15.329483863662498 -1.5228787452805572 0.42618770028835895 0.8372451860944096 9.38509791492552 0.6143951047359163 0.10204503175606551 54.64079885777777 0.691930754076114 0.07104668457406976 399.9665865268521 0.029999999999984827 1.5228787452805572 8.54785272883111 VTRSPPT(ph)QVAISSDSAR ddPTM_PC-9_Lapatinib_30min_R1 1 VTRSPPTQVAISSDSAR 17 1 Q6ZUT6;Q6ZUT6-4;H0YM82;Q6ZUT6-3 Q6ZUT6 C15orf52 Uncharacterized protein C15orf52 1 VT(0.013)RS(0.192)PPT(0.361)QVAIS(0.332)S(0.102)DSAR 91.065 0.023484 27904000.0 18321.0 9937.3 13827.0 13723.0 12947.0 13930.0 9506.3 9532.7 16187.0 8977.7 True False 18059.73918034009 9914.290792395888 12690.197433763497 14732.235198586002 12185.48291478136 13334.24637241601 9998.489699316866 9975.624042832293 14363.849603333323 10529.483482966694 1.7151590777985377 0.9415742765002681 1.2052060724813463 1.3991412990407368 1.1572726178348196 1.266372314842083 0.9495707662670438 0.9473991823976582 1.3641551958906053 1.0 13.362147047172408 -7.239323435507879 23.239244669003902 1.060897895993891 1.2616987407338351 0.19115508309941476 0.21495667792855813 582.614234209069 612206.0946844555 0.07934746194442836 0.061389554537984004 5.763370835248595e-08 7.239323435507879 0.20080084473994408 VTS(ph)AEIK ddPTM_PC-9_AZD4547_30min_R2 1 VTSAEIK 7 0 Q8N4X5-2;Q8N4X5;Q8N4X5-4;Q8N4X5-3 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 VT(0.015)S(0.985)AEIK 87.639 0.017806 7546900.0 51809.0 63881.0 94053.0 106900.0 97711.0 107930.0 81709.0 103280.0 89980.0 95618.0 True False 68283.18430585517 84529.28398895903 92805.7957668614 82255.85658853617 84145.5142646309 101181.12003810432 88980.94270869295 87320.44913829703 94736.15910218917 92270.44292385393 0.7400331259079984 0.9161035897347617 1.0058019971081018 0.8914648503033384 0.9119444060117049 1.0965713053052526 0.9643493613889376 0.9463534190505417 1.0267227088133744 1.0 16.4935809615895 -4.7754255926344635 2.648092498931735 0.9765067247836708 0.689691467350465 0.6283310390821695 0.0556458040277197 0.32934967767161066 3.004634768676927 0.014793725007634935 0.21435429998450775 1.6771596577090906e-05 4.7754255926344635 -0.2868152574332058 VTS(ph)AEIK ddPTM_PC-9_Lapatinib_30min_R1 2 VTSAEIK 7 0 Q8N4X5-2;Q8N4X5;Q8N4X5-4;Q8N4X5-3 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 VT(0.087)S(0.913)AEIK;VT(0.024)S(0.976)AEIK 82.287 0.022701 12229100.0 142679.0 156504.0 168471.0 155627.0 205220.0 202865.0 178670.0 175715.0 208018.0 157521.0 True False 140644.37129587602 156141.62460357716 154619.964696866 167072.32873645323 193149.36307804374 194188.9368514122 187920.65836097606 183879.36037914467 184588.82231334964 184748.29496646073 0.7612756118881023 0.8451586772799347 0.8369222824217986 0.9043240630003303 1.0454730481442773 1.0511000217169275 1.0171712729207663 0.995296657068073 0.9991368112320601 1.0 17.495201524303326 -5.9836110180147735 2.3588993576873123 1.0194960036984668 0.8132555941008774 0.9156135730278361 0.027878458547350635 0.08195682389934399 0.9183461527466944 0.009199884182328368 0.014303112355120154 1.0384581090784878e-06 5.9836110180147735 -0.20624040959758938 VTS(ph)LRSPGASVSSSLTSLCSSSSDPAPSDR ddPTM_PC-9_Lapatinib_30min_R1 1 VTSLRSPGASVSSSLTSLCSSSSDPAPSDR 30 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 VT(0.405)S(0.435)LRS(0.156)PGAS(0.001)VS(0.001)S(0.001)SLTSLCSSSSDPAPSDR 59.222 0.00058286 4352900.0 6588.8 2997.4 3490.0 3972.7 2689.1 3216.5 2088.5 3159.3 3860.6 609.31 True False 6494.842503762065 2990.459704459708 3203.0656717895877 4264.8656105387045 2530.932424974015 3078.937793027718 2196.632310891018 3306.092611591686 3425.778574079733 714.6284216454593 9.088418969969654 4.184635838543981 4.4821414524969585 5.967948490935594 3.5416061666655323 4.30844575973951 3.0738104507978954 4.626309997549889 4.79378998975684 1.0 9.481049482583385 -1.5228787452803376 0.09685151502259134 0.07380388273418656 18.61496627954844 0.5270803343895482 1.3519617023770212 123.81007354046534 0.8570692262639266 19.522624816541033 304.784145419937 0.029999999999999995 1.5228787452803376 18.541162396814254 VTS(ph)PTKV ddPTM_PC-9_AZD4547_30min_R2 1 VTSPTKV 7 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4 E7EX44;Q05682-5 CALD1 Caldesmon 1 VTS(0.995)PT(0.004)KV 76.47800000000001 0.045831000000000004 5666500.0 66279.0 68108.0 73068.0 66734.0 71155.0 73796.0 92635.0 98363.0 85920.0 75866.0 True False 87354.34331115795 90122.57907546882 72099.07057821685 51349.50733002213 61276.35647470408 69181.52445410872 100879.33554222614 83163.25850687751 90461.55579084346 73209.95443181304 1.193203082683501 1.2310153690835584 0.9848260545684283 0.7014006186528706 0.8369948724906832 0.9449742865028504 1.377945613068016 1.1359556108498179 1.2356455688699872 1.0 16.159752206105395 -7.232616047511886 24.331788832512203 1.1987163733569122 0.9741581401467534 0.2602543361281241 0.16883313773979927 734.5540875753368 620088.9628089659 0.07149234570204674 0.05536645643482379 5.853073158818549e-08 7.232616047511886 -0.22455823321015878 VTS(ph)PTKV ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VTSPTKV 7 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4 E7EX44;Q05682-5 CALD1 Caldesmon 1 VT(0.252)S(0.747)PT(0.001)KV;VT(0.117)S(0.882)PT(0.002)KV 87.181 0.02661 200784000.0 1372970.0 1886080.0 1424840.0 1371180.0 1564630.0 1187080.0 1708360.0 1376750.0 1146040.0 1093600.0 True False 1605386.7036064225 2073317.5577315276 1458813.5893357876 1294357.230025541 1258051.9832904318 1124827.4350650928 1546531.7733446723 1340611.7712872056 1162798.6669053321 1291861.0230671645 1.242693041233552 1.6049075873572005 1.1292341538970196 1.0019322565769884 0.9738291974345178 0.8707031290366691 1.1971347890602528 1.0377368365091595 0.9000957890536788 1.0 20.301019444219584 -5.4544292857046175 4.8457473041725185 1.0043646623478806 1.4209107663202094 0.6774819341138242 0.11601994407258585 0.1151649805046474 5.15855903500347 0.030158201409024612 0.06375939505301037 3.5121310637454342e-06 5.4544292857046175 0.41654610397232883 VTS(ph)PTTYVLDEDEPR ddPTM_PC-9_AZD4547_30min_R2 3 VTSPTTYVLDEDEPR 15 0 J3KNS1;Q9UPW5;Q9UPW5-2;Q9UPW5-3 J3KNS1 AGTPBP1 Cytosolic carboxypeptidase 1 1 VT(0.039)S(0.935)PT(0.02)T(0.006)Y(0.001)VLDEDEPR;VT(0.135)S(0.706)PT(0.126)T(0.029)Y(0.005)VLDEDEPR;VT(0.083)S(0.512)PT(0.254)T(0.076)Y(0.076)VLDEDEPR 125.36 2.6649000000000002e-05 10418900.0 22278.000000000004 22336.199999999997 25205.0 39056.0 29911.1 26848.9 27424.0 41476.0 25904.699999999997 29159.6 True False 29361.940588813555 29555.939841802512 24870.76523134556 30052.242609184883 25758.460068168377 25170.03403864595 29864.68287267247 35066.83722366387 27273.969556506778 28138.73127949149 1.0434706631643191 1.050365048382403 0.8838623527234953 1.0680027578602318 0.9154094337914254 0.894497828940524 1.0613372214986436 1.24621244914556 0.9692679206324067 1.0 14.7802696612849 -7.506909806839143 24.760333014350085 1.0953990615527665 0.9766791111993728 0.1847766608703415 0.0922540773632986 845.7335996336493 1311342.355506776 0.038586343244391794 0.02514198501668928 3.112362637459248e-08 7.506909806839143 -0.11871995035339367 VTS(ph)PTTYVLDEDEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTSPTTYVLDEDEPR 15 0 J3KNS1;Q9UPW5;Q9UPW5-2;Q9UPW5-3 J3KNS1 AGTPBP1 Cytosolic carboxypeptidase 1 1 VT(0.007)S(0.938)PT(0.053)T(0.002)YVLDEDEPR 134.4 1.1964000000000001e-05 2912400.0 5477.5 5765.3 8374.0 8331.0 9454.2 7501.8 9388.8 7931.9 8570.4 7018.8 True False 6404.732564443639 6337.6408824596765 8573.667918571853 7864.241079466423 7601.717377542564 7108.392401835861 8499.424894974405 7723.696029542741 8695.72588639615 8291.252879209767 0.7724686073082442 0.7643767443580507 1.0340618050705266 0.9484985193475316 0.916835789269411 0.8573363405258189 1.0251074257168813 0.9315475166497249 1.0487830986557647 1.0 13.017374406413248 -5.248874681711494 24.7885815663882 0.9630656091879934 0.7684226323113595 0.6682562375235732 0.05670581404775596 408.45048816019784 805817.8666764853 0.014520505746049786 0.03783649764594272 5.638003203341118e-06 5.248874681711494 -0.1946429768766339 VTS(ph)PTTYVLDEDEPR ddPTM_PC-9_Lapatinib_30min_R1 3 VTSPTTYVLDEDEPR 15 0 J3KNS1;Q9UPW5;Q9UPW5-2;Q9UPW5-3 J3KNS1 AGTPBP1 Cytosolic carboxypeptidase 1 1 VT(0.001)S(0.681)PT(0.308)T(0.01)YVLDEDEPR;VT(0.028)S(0.939)PT(0.033)TYVLDEDEPR;VT(0.028)S(0.875)PT(0.062)T(0.031)Y(0.004)VLDEDEPR 178.23 2.1816999999999998e-05 7128800.0 25709.699999999997 22149.8 26358.899999999998 22319.1 24543.100000000002 26938.1 27226.1 24635.0 30015.9 22935.8 True False 25343.074963418447 22098.513498979657 24191.772990296424 23960.52106833498 23099.523111591137 25786.020258778164 28635.73423966959 25779.632034489037 26635.19326056047 26900.22246996755 0.9421139543255613 0.8214992840171227 0.8993149784283404 0.890718323801427 0.8587112295216272 0.9585801860027989 1.0645166325906648 0.9583427075099626 0.9901476945143124 1.0 14.715330483743681 -6.922918636639162 4.677139904485466 1.0013991442819916 0.8810682625434053 0.6957448176670379 0.037820880292600355 0.11420341050740562 4.641058399003428 0.013207362079002777 0.011524215759177966 1.194211814388391e-07 6.922918636639162 -0.1203308817385863 VTSFSTPPT(ph)PER ddPTM_PC-9_AZD4547_30min_R2 2 VTSFSTPPTPER 12 0 Q6ICG6-2;B0QY16;Q6ICG6-3;Q6ICG6 Q6ICG6-2 KIAA0930 Uncharacterized protein KIAA0930 1 VTSFSTPPT(1)PER;VTSFSTPPT(1)PER 159.58 0.00040776 33101000.0 108471.0 104454.0 131218.0 170230.0 163094.0 146945.0 130629.0 169815.0 132742.0 138927.0 True False 142962.52166303957 138216.71279070017 129477.96358368173 130986.10352728266 140451.21330736286 137756.50592049697 142254.7279380955 143573.99371049492 139758.471121836 134063.2080160879 1.0663814761607355 1.0309816901749347 0.9657978911570135 0.9770473604627155 1.0476492050713002 1.027548929785164 1.0611019238106294 1.0709425489300963 1.0424819246833525 1.0 17.032553836246024 -6.299021972834029 24.525901207669246 1.0454383604201503 1.0083860528600714 0.18709269303701015 0.031565825298095256 697.5919553982267 455237.1620765431 0.010414874039464816 0.011809684485966 5.023171744835535e-07 6.299021972834029 -0.03705230756007882 VTSFSTPPT(ph)PER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VTSFSTPPTPER 12 0 Q6ICG6-2;B0QY16;Q6ICG6-3;Q6ICG6 Q6ICG6-2 KIAA0930 Uncharacterized protein KIAA0930 1 VTSFST(0.001)PPT(0.999)PER;VTSFSTPPT(1)PER;VTSFSTPPT(1)PER 134.61 0.00014161 18446800.0 53998.0 54344.0 65613.0 73774.0 83273.0 76382.0 78631.0 76266.0 69655.0 58435.0 True False 63138.794890885874 59738.91317301591 67177.46275868811 69640.68195853497 66956.25343023229 72376.39345717378 71182.50244085856 74264.0983105065 70673.5726006864 69028.80292879461 0.9146731829612565 0.8654200947775161 0.9731801785405982 1.0088641118457686 0.9699755839500763 1.048495561075169 1.031200012468499 1.07584218702318 1.0238272953043734 1.0 16.0749108453817 -5.566568159205874 0.9210361793492197 1.0370095930538685 0.8699704030573654 0.7397731600044667 0.030587552125185775 0.40130400927377663 0.5589541907365193 0.012004799861286818 0.05310565494046554 2.7128878516857333e-06 5.566568159205874 -0.16703918999650313 VTSGGVSES(ph)PSGFSK ddPTM_PC-9_AZD4547_30min_R2 1 VTSGGVSESPSGFSK 15 0 E7EPP6;O14757-2;O14757-3;O14757 E7EPP6 CHEK1 Serine/threonine-protein kinase Chk1 1 VTSGGVS(0.006)ES(0.975)PS(0.019)GFSK 120.92 0.0012472000000000002 0.0 6926.0 6512.9 8993.3 12179.0 11058.0 11044.0 8080.3 11529.0 9551.0 11846.0 True False 9128.323930250594 8618.067558298879 8874.042965882169 9371.319713674286 9522.787574974043 10353.41693413159 8799.431046384752 9747.45796006415 10055.846361247053 11431.275145641774 0.7985394292368869 0.7539025566701154 0.7762951073105294 0.8197965313823405 0.8330468345523684 0.9057097132404234 0.769768108480844 0.8527008435957745 0.8796784464663062 1.0 13.480698723056763 -14.52287874527197 0.10214766405936282 1.59613288457965 0.6987580421487225 0.7286031632957513 0.03691873659950315 98.16625106647487 0.6764589776068989 12.299036888947851 0.6068894462061768 3.0000000000577957e-15 14.52287874527197 -0.8973748424309276 VTSGGVSES(ph)PSGFSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTSGGVSESPSGFSK 15 0 E7EPP6;O14757-2;O14757-3;O14757 E7EPP6 CHEK1 Serine/threonine-protein kinase Chk1 1 VTSGGVS(0.057)ES(0.924)PS(0.018)GFSK 131.72 0.00015404 0.0 25694.0 19486.0 16740.0 19465.0 27337.0 19042.0 19552.0 24452.0 24925.0 16673.0 True False 30043.486720367833 21420.441301512383 17139.14508680354 18374.43915638146 21980.51109029647 18043.403998474823 17699.893015778336 23810.16090903555 25289.480971532736 19695.682916604615 1.5253843620237921 1.0875703773365326 0.8701980611372574 0.9329170881853877 1.1160065473924548 0.9161095898463706 0.8986686620983468 1.2089025300545526 1.2840113784636642 1.0 14.265591820533789 -4.772011333883739 4.347070875557872 1.0241496011297642 1.565918310412033 0.562637046509868 0.13053449651929544 0.1606586545975175 6.37427493638724 0.03507452049821291 0.2712250870287686 1.6903968163901673e-05 4.772011333883739 0.541768709282269 VTSLANLIS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 1 VTSLANLISPVR 12 0 Q7Z628;Q7Z628-2 Q7Z628 NET1 Neuroepithelial cell-transforming gene 1 protein 1 VTSLANLIS(1)PVR 99.834 0.0032219 8423200.0 24340.0 25181.0 28677.0 52394.0 39218.0 32630.0 26567.0 37536.0 33755.0 34262.0 True False 32079.613696549164 33320.265808706434 28296.72424278105 40315.372779230696 33773.25765195621 30589.64094175244 28931.41153290145 31735.673691470914 35539.22038780171 33062.49780854118 0.9702719341507797 1.007796386155031 0.8558556103849793 1.2193686336915492 1.0214974636075869 0.9252065926443732 0.8750522026629056 0.9598692111904654 1.0749103287235822 1.0 15.012908101150952 -6.741982722134036 24.48158722026655 0.9587522761572908 1.0170772845425156 0.05499150554242582 0.09619613650591054 560.6421471686247 705432.9830169629 0.03279862763881346 0.03274808934074768 1.8114121559664454e-07 6.741982722134036 0.05832500838522481 VTSLANLIS(ph)PVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTSLANLISPVR 12 0 Q7Z628;Q7Z628-2 Q7Z628 NET1 Neuroepithelial cell-transforming gene 1 protein 1 VTSLANLIS(1)PVR 108.36 0.0014417 9845900.0 23732.0 21864.0 31111.0 29105.0 30981.0 27280.0 26871.0 25499.0 30149.0 20979.0 True False 27749.358871634213 24034.513425857876 31852.80422912452 27474.341209683123 24910.495448969363 25849.388776304655 24325.584350807057 24829.67826842375 30589.872088695683 24782.32663032738 1.1197237162420386 0.9698247377809004 1.285303220487161 1.108626386033561 1.0051717831240725 1.0430573836708075 0.9815698386058157 1.0019107018805258 1.2343422207687844 1.0 14.597024017409977 -6.143901821167713 6.609920792431514 1.0414974769083658 1.123152173518283 0.12921704725487781 0.09760430514645185 0.5264560248846178 26.714053998515364 0.028970507300120085 0.0375961464498181 7.179565778638239e-07 6.143901821167713 0.0816546966099172 VTSLANLIS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 2 VTSLANLISPVR 12 0 Q7Z628;Q7Z628-2 Q7Z628 NET1 Neuroepithelial cell-transforming gene 1 protein 1 VTSLANLIS(1)PVR;VTSLANLIS(1)PVR 97.2 0.0040452 13199300.0 32663.0 28572.3 38311.0 31461.0 26679.0 26076.0 21932.9 25750.0 34961.0 24557.8 True False 32197.219630339387 28506.14259482688 35161.21746473663 33774.746890819384 25109.793672932105 24960.790266124895 23068.478243496094 26946.43900499665 31023.32402434892 28802.583008788373 1.1178587566439866 0.9897078531508428 1.2207661185806868 1.1726290965124164 0.8717896469657076 0.8666163815415009 0.8009169954117427 0.9355563352347472 1.0771021479178775 1.0 14.813910577566656 -6.26294816166445 24.98587702534451 0.9129517078199517 1.1223828213956109 0.5388952048378388 0.09014093560079266 108.85325169901968 1802640.7039471054 0.029035437916020965 0.03471507364573726 5.458230078265556e-07 6.26294816166445 0.20943111357565913 VTSLRS(ph)PGASVSSSLTSLCSSSSDPAPSDR ddPTM_PC-9_AZD4547_30min_R2 1 VTSLRSPGASVSSSLTSLCSSSSDPAPSDR 30 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 VT(0.042)S(0.042)LRS(0.886)PGAS(0.021)VS(0.004)S(0.002)S(0.001)LT(0.002)SLCSSSSDPAPSDR 79.163 6.293899999999999e-07 16744000.0 2653.3 2432.6 8536.2 17400.0 15570.0 7711.6 6244.3 9970.2 3073.9 8335.4 True False 3496.99420793155 3218.8903779142734 8423.004410546004 13388.69882732018 13408.37425776323 7229.392432927308 6800.030603188038 8429.534682403644 3236.3800785087724 8043.580183098301 0.43475593309552185 0.40018130044603983 1.0471710629857305 1.664519843471368 1.666965947071403 0.8987779407132885 0.8453984977332245 1.047982924334656 0.4023556681027768 1.0 12.973622069989137 -8.21713855151303 24.52491679197085 0.701176953705943 1.0180092423805227 0.07327583094796886 0.4225358476996276 937.3994168271419 518945.0162049161 0.31976215786683204 0.12085717829762498 6.065427954036683e-09 8.21713855151303 0.3168322886745797 VTSLRS(ph)PGASVSSSLTSLCSSSSDPAPSDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VTSLRSPGASVSSSLTSLCSSSSDPAPSDR 30 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 VT(0.194)S(0.194)LRS(0.46)PGAS(0.02)VS(0.083)S(0.036)S(0.005)LT(0.005)S(0.001)LCSSSSDPAPSDR;VT(0.225)S(0.225)LRS(0.531)PGAS(0.002)VS(0.001)S(0.001)S(0.005)LT(0.002)S(0.001)LCS(0.001)S(0.002)S(0.001)S(0.002)DPAPSDR 66.738 6.5036e-05 14303300.0 11669.199999999999 3882.22 11142.6 21049.2 27987.0 25466.4 19310.8 27153.0 22979.0 16717.8 True False 13644.565082794285 4267.621144901845 11408.281842545823 19869.881566427146 22503.14825636054 24130.897152964986 17481.541225915105 26440.262520981614 23315.02440300304 19748.604801968013 0.690912862939794 0.21609734903787037 0.5776753323560837 1.0061410294891844 1.1394804079586436 1.2219038962469015 0.8852038612962174 1.3388420491531006 1.1805909651237552 1.0 14.26946311302239 -5.764311400735734 2.9850104290804738 1.1334218486008774 0.43970097817616455 0.7672077501128165 0.15727160941653787 0.10686915617594037 1.9533924516076477 0.04389413112865056 0.07679281573761138 1.7206343917815713e-06 5.764311400735734 -0.6937208704247129 VTSLRS(ph)PGASVSSSLTSLCSSSSDPAPSDR ddPTM_PC-9_Lapatinib_30min_R1 2 VTSLRSPGASVSSSLTSLCSSSSDPAPSDR 30 1 Q9P206-2;Q9P206;Q9P206-3 Q9P206-2 KIAA1522 Uncharacterized protein KIAA1522 1 VT(0.137)S(0.137)LRS(0.702)PGAS(0.006)VS(0.006)S(0.008)S(0.001)LT(0.001)SLCSSSSDPAPSDR;VT(0.093)S(0.245)LRS(0.658)PGAS(0.002)VS(0.001)S(0.001)SLTSLCSSSSDPAPSDR 77.358 8.6515e-07 6024100.0 18384.9 13228.1 13571.0 14530.0 14817.2 13832.9 12622.1 12671.4 18477.0 13419.9 True False 18122.727954622263 13197.471147182046 12455.244765574926 15598.58467065909 13945.68142773604 13241.299113064853 13275.610577590382 13260.159503219988 16395.925688564264 15739.511834107263 1.1514161395622582 0.8384930413523591 0.791336154313542 0.9910462811722797 0.8860301116528899 0.8412776236408537 0.8434575809919563 0.8424759066850752 1.041704842016419 1.0 13.94210317544986 -8.269355663707527 24.402252732047213 1.0208524486773731 0.891607976576261 0.19422881495945743 0.09921200752768153 743.1903139090815 2290872.099376273 0.08783696486691835 0.024385279840291516 5.378291491094117e-09 8.269355663707527 -0.12924447210111212 VTSPT(ph)TYVLDEDEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VTSPTTYVLDEDEPR 15 0 J3KNS1;Q9UPW5;Q9UPW5-2;Q9UPW5-3 J3KNS1 AGTPBP1 Cytosolic carboxypeptidase 1 1 VT(0.017)S(0.121)PT(0.651)T(0.177)Y(0.034)VLDEDEPR;VT(0.021)S(0.103)PT(0.37)T(0.137)Y(0.37)VLDEDEPR;VT(0.243)S(0.073)PT(0.525)T(0.159)YVLDEDEPR 135.86 6.404800000000001e-05 6700400.0 23147.3 20484.899999999998 29503.1 26082.6 32733.9 28179.4 27747.9 25109.6 29256.2 23248.300000000003 True False 27065.680709985612 22518.50549201226 30206.565795129816 24621.276482930116 26319.927277267292 26701.622657001437 25119.41803460082 24450.49960582033 29684.016577707363 27463.03275655847 0.98553138504057 0.8199569833245964 1.0998991285081638 0.8965243096485871 0.9583765751792948 0.9722750904349703 0.9146629309758963 0.8903058821856186 1.0808717609899985 1.0 14.745203331372867 -8.265624833749046 24.97941718239045 1.0404358820356694 0.942476395681255 0.2301171840217382 0.07187802511871724 529.7711978432559 3161686.4668495683 0.058000548571256756 0.01700184161671777 5.42469301362122e-09 8.265624833749046 -0.09795948635441443 VTSPTT(ph)YVLDEDEPR ddPTM_PC-9_Lapatinib_30min_R1 1 VTSPTTYVLDEDEPR 15 0 J3KNS1;Q9UPW5;Q9UPW5-2;Q9UPW5-3 J3KNS1 AGTPBP1 Cytosolic carboxypeptidase 1 1 VT(0.007)S(0.244)PT(0.271)T(0.404)Y(0.073)VLDEDEPR 89.9 0.010731000000000001 2885700.0 8107.8 6250.7 7762.7 7240.6 10700.0 8183.6 9793.7 7432.3 10022.0 7909.2 True False 7992.18128521158 6236.226888191861 7124.480770888549 7773.097877933534 10070.647037009392 7833.606504903352 10300.769865057868 7777.631790945112 8893.21682366136 9276.294681653451 0.861570439436171 0.6722756339905629 0.7680308803664102 0.8379528836343543 1.0856325055010383 0.8444758142921622 1.1104401292286037 0.8384416470002427 0.9587035695675193 1.0 13.17933293571622 -6.030817072171078 5.225298040819293 0.9658798801445454 0.7631153552355773 0.5069957104681424 0.092516010677675 0.1489725431251729 11.093062657662154 0.025829365190349212 0.03522341496874533 9.31500147130109e-07 6.030817072171078 -0.20276452490896812 VTSSEPPNPAS(ph)SSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VTSSEPPNPASSSK 14 0 Q92575 Q92575 UBXN4 UBX domain-containing protein 4 1 VTSSEPPNPAS(0.907)S(0.072)S(0.021)K;VTSSEPPNPAS(0.891)S(0.068)S(0.04)K 148.33 4.3899e-08 0.0 44969.0 49394.0 43031.0 40668.0 59046.0 34549.0 40786.0 28561.0 24977.0 24901.0 True False 52581.36352176467 54297.50988642624 44057.02223597624 38389.50380743493 47476.36016525755 32737.189619961486 36922.454814931196 27811.304012880926 25342.24137315841 29415.354183792475 1.7875482033371675 1.8458900595643193 1.497755966516669 1.3050838540841745 1.6139992695181107 1.1129286227666537 1.2552102750227991 0.9454689492810744 0.8615310634988612 1.0 14.844281787078065 -6.119043007690064 0.4194067370321847 0.8832113799754557 2.010807131741785 0.819619008549246 0.14171006004902106 0.7792691701721663 0.2308946695601976 0.1339735267512877 0.39523236300200487 7.602509864191958e-07 6.119043007690064 1.127595751766329 VTSSITIYPSDS(ph)SSPR ddPTM_PC-9_AZD4547_30min_R2 1 VTSSITIYPSDSSSPR 16 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 VTSSITIYPSDS(0.486)S(0.486)S(0.028)PR 77.051 0.010948000000000001 4817600.0 19019.0 17554.0 19287.0 33433.0 23978.0 22136.0 19197.0 31371.0 24538.0 16170.0 True False 25066.646380224687 23227.987212820484 19031.241778098072 25725.538384700896 20649.068590407624 20751.832420675215 20905.49581048328 26523.33278386439 25835.028584680153 15603.893221764942 1.606435395575555 1.4886020355754004 1.2196470142177418 1.648661524344314 1.3233279859673397 1.3299137674006716 1.3397615270350254 1.699789431195836 1.6556783757430749 1.0 13.929618410622789 -4.881558065023772 4.4425101453623395 1.4241878797937226 1.6028020373011196 0.07779651534002385 0.20702895464827697 0.6151329235580533 19.321403268289455 0.050941834183050906 0.25458045836391113 1.3135358639234294e-05 4.881558065023772 0.17861415750739695 VTSSITIYPSDS(ph)SSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VTSSITIYPSDSSSPR 16 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 VTSSITIYPS(0.001)DS(0.333)S(0.333)S(0.333)PR;VTSSITIYPS(0.086)DS(0.517)S(0.383)S(0.013)PR 111.64 0.0015404000000000001 5725700.0 30589.3 36557.0 41910.0 39888.0 46668.0 35431.0 38856.9 33521.4 28075.2 26682.8 True False 35767.46432378562 40186.13736320374 42909.29334456009 37653.204678640825 37523.740409041086 33572.93598728924 35176.09313240572 32641.49876885916 28485.746686939834 31520.18041907143 1.1347480835529848 1.2749336085300114 1.3613276565700627 1.1945745290169272 1.1904671835678065 1.0651251211422565 1.1159864145676737 1.035574617114478 0.903730445327794 1.0 14.943988172242047 -7.0899819216382 0.8285237036934021 0.9669325191062712 1.2588112395705064 0.7223753131213724 0.06742084060164812 0.33805452796465946 0.4727639620528373 0.05248117114543811 0.03614624015695105 8.128643525369208e-08 7.0899819216382 0.29187872046423524 VTSSITIYPSDSS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 VTSSITIYPSDSSSPR 16 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 VTSSITIYPSDS(0.148)S(0.792)S(0.06)PR 181.69 2.2305e-06 4743300.0 48582.0 49735.0 54987.0 45357.0 49349.0 50329.0 40214.0 42997.0 52202.0 38963.0 True False 47889.21177115232 49619.841663209314 50466.181115958185 48692.705086516486 46446.38884386696 48176.54599262922 42296.084151386814 44994.79758826566 46322.461048570185 45697.702635065936 1.0479566588628624 1.085827925737644 1.1043483196293806 1.0655394533805809 1.016383453995049 1.0542443758575546 0.9255625931385684 0.9846183723410878 1.0136715497164805 1.0 15.479834017911381 -6.637410247655591 1.3850284303875464 0.9833453973437672 1.079466709096946 0.6089618470059035 0.03135149207783367 0.27258250436498904 1.0896437749609482 0.01403912276980899 0.014144265223766135 2.3045691946703743e-07 6.637410247655591 0.09612131175317884 VTSSMS(ph)SPSMQPK ddPTM_PC-9_AZD4547_30min_R2 2 VTSSMSSPSMQPK 13 0 A0A2R8Y7R9;Q13136-2;Q13136 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 VT(0.002)S(0.007)S(0.052)MS(0.434)S(0.434)PS(0.073)MQPK;VTSSMS(0.443)S(0.119)PS(0.439)MQPK 120.59 0.00012568 99446000.0 25374.0 35147.0 48762.0 67843.0 62394.0 55150.0 60692.0 76055.0 56424.0 61590.0 True False 33442.40418801308 46507.58041295441 48115.38401947517 52202.84451390138 53731.67009883616 51701.4617817238 66093.47042401679 64302.44732003463 59406.45744812101 59433.752846536976 0.562683703894052 0.782511253042374 0.8095632820581463 0.8783366692103993 0.904059856990285 0.8699006760555974 1.1120527858080202 1.0819180051791284 0.9995407424719343 1.0 15.858994859978885 -4.14341506703134 0.3743413323267388 1.0573285653055184 1.1093802268426385e-17 0.8338300403650571 0.06250661056238324 3.964025763048115 0.3057074566403991 0.056411758454996436 2.069610835609956 7.187617095488156e-05 4.14341506703134 -1.0573285653055184 VTSSMS(ph)SPSMQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VTSSMSSPSMQPK 13 0 A0A2R8Y7R9;Q13136-2;Q13136 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 VTS(0.001)S(0.004)MS(0.38)S(0.234)PS(0.38)MQPK;VTS(0.004)S(0.011)MS(0.577)S(0.274)PS(0.133)MQPK;VTSS(0.001)MS(0.548)S(0.141)PS(0.31)MQPK;VTS(0.023)S(0.016)MS(0.37)S(0.37)PS(0.221)MQPK 116.71 0.00016127 126044300.0 82398.0 99915.0 133648.0 157184.0 166730.0 140178.0 146651.0 151780.0 124468.0 107667.0 True False 96346.35396531735 109833.90088476898 136834.67518286261 148377.4900774034 134060.4533813198 132826.8189107344 132759.1556187045 147795.93582420322 126288.10902967837 127186.17480849697 0.7575222237038354 0.8635679235588684 1.0758612356169472 1.1666164997949973 1.054048945045901 1.0443495066246822 1.0438175046823974 1.1620440354208166 0.9929389669893696 1.0 16.956582332014854 -5.130200709301725 3.0582476400664125 1.0753078492151928 0.7711026496273456 0.777102309830616 0.05615193912040526 0.11167077680567354 1.9160075538707926 0.01458892278524702 0.05333632484291262 7.409677237437892e-06 5.130200709301725 -0.3042051995878472 VTSSMS(ph)SPSMQPK ddPTM_PC-9_Lapatinib_30min_R1 4 VTSSMSSPSMQPK 13 0 A0A2R8Y7R9;Q13136-2;Q13136 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 VTSSMS(0.941)S(0.045)PS(0.013)MQPK;VTSSMS(0.9)S(0.079)PS(0.021)MQPK;VT(0.001)S(0.004)S(0.02)MS(0.325)S(0.325)PS(0.325)MQPK;VTSSMS(0.78)S(0.219)PS(0.001)MQPK 257.95 5.756099999999999e-44 22539100.0 130963.0 107732.0 115372.0 107761.0 97546.0 88903.0 69913.0 77316.0 101512.0 70898.0 True False 129095.4436043273 107482.55317303422 105886.55950879902 115686.10342015777 91808.53606281482 85100.82593301509 73532.7530530638 80908.3836159348 90078.64959125052 83152.62483435322 1.5525119484982695 1.2925936299322864 1.2734000847205202 1.391250169800579 1.1040966685742617 1.0234292194929846 0.8843106660739456 0.9730105787653831 1.0832929179408888 1.0 16.34347418456212 -6.424572174451743 2.3215410870873017 0.9826893271042583 1.3693483492322236 0.81877666466839 0.08537071106124974 0.1288691234471022 1.3675859276395068 0.030297739425507984 0.034689303283614976 3.7620782591514377e-07 6.424572174451743 0.3866590221279653 VTSSMSS(ph)PSMQPK ddPTM_PC-9_AZD4547_30min_R2 3 VTSSMSSPSMQPK 13 0 A0A2R8Y7R9;Q13136-2;Q13136 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 VTSSMS(0.014)S(0.963)PS(0.024)MQPK;VTSSMS(0.037)S(0.732)PS(0.231)MQPK;VTSS(0.002)MS(0.199)S(0.668)PS(0.129)MQPK 143.42 7.5602e-05 36233600.0 45512.0 52070.0 72131.0 114922.0 100411.0 97745.0 92741.0 107794.0 86295.0 97041.0 True False 59983.86929159182 68900.60921565241 71174.4958104418 88428.50842720059 86470.66587002348 91632.9896981795 100994.76933687695 91136.91415969776 90856.37752526578 93643.6241269817 0.6405547612110045 0.7357746975087432 0.760057040444403 0.9443089078578446 0.9234015308161119 0.978528869983975 1.0785012890992667 0.9732313866464115 0.9702355966281657 1.0 16.51489314920706 -5.5854840824549745 0.960109744693655 1.0031480128090668 0.6262002526208241 0.9136516495318086 0.038839484108940114 0.20992559726209664 0.32685200005255344 0.015291019561551341 0.06354892160359672 2.5972629332448516e-06 5.5854840824549745 -0.3769477601882427 VTSSMSS(ph)PSMQPK ddPTM_PC-9_Lapatinib_30min_R1 2 VTSSMSSPSMQPK 13 0 A0A2R8Y7R9;Q13136-2;Q13136 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 VTSSMS(0.161)S(0.806)PS(0.032)MQPK;VTSSMS(0.346)S(0.654)PSMQPK 249.28 2.2328e-34 5902600.0 67357.0 60056.0 57446.0 55842.0 52841.0 45861.0 38873.0 39732.0 47867.0 34120.0 True False 66396.47682823893 59916.94402182962 52723.01162797265 59948.806963451105 49732.99626940309 43899.631937212565 40885.653732950195 41578.093768797175 42475.71439814394 40017.5965379578 1.6591820242192714 1.4972649335648318 1.3174957066190474 1.4980611568360434 1.2427781918944074 1.0970082097652354 1.0216918873218441 1.038995276224528 1.0614259244143898 1.0 15.288346900943646 -6.205557408057779 0.6539982000826544 0.9956673836503825 1.6174623904643093 0.8934969634169729 0.07387220652273832 0.28876241535482744 0.2574854643660806 0.05063956520172516 0.10295424221884152 6.229347981428563e-07 6.205557408057779 0.6217950068139267 VTSSMSSPS(ph)MQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTSSMSSPSMQPK 13 0 A0A2R8Y7R9;Q13136-2;Q13136 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 VTS(0.012)S(0.059)MS(0.309)S(0.309)PS(0.311)MQPK 63.216 0.0277 48322000.0 8249.4 10129.0 12888.0 13944.0 15783.0 11538.0 13809.0 14859.0 13290.0 10799.0 True False 9645.86048692311 11134.540179771055 13195.298798012178 13162.762887057952 12690.434449213502 10932.926968511845 12500.911551497691 14468.966994411878 13484.341107790176 12756.77321516303 0.7561363931325353 0.8728335913768737 1.03437590176236 1.031825420507778 0.9947997220903264 0.8570291863083908 0.9799430734285364 1.1342184069881944 1.057033850202992 1.0 13.63897582971806 -5.008902839206265 2.7671596820799236 1.0093933626443639 0.7550342650263143 0.6066986763426752 0.06637927452529 0.22706040130407415 3.1683159601187634 0.019640709040495686 0.10408299053518406 9.79709142397194e-06 5.008902839206265 -0.25435909761804953 VTSSMSSPS(ph)MQPK ddPTM_PC-9_Lapatinib_30min_R1 5 VTSSMSSPSMQPK 13 0 A0A2R8Y7R9;Q13136-2;Q13136 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 VTSS(0.003)MS(0.059)S(0.216)PS(0.721)MQPK;VT(0.005)S(0.031)S(0.199)MS(0.189)S(0.189)PS(0.386)MQPK;VT(0.001)S(0.003)S(0.017)MS(0.297)S(0.297)PS(0.385)MQPK;VTS(0.001)S(0.006)MS(0.248)S(0.248)PS(0.498)MQPK;VTSS(0.004)MS(0.173)S(0.268)PS(0.556)MQPK 105.25 0.00074685 94910000.0 139970.0 113906.0 124371.0 116491.0 99292.0 94613.0 81692.0 80586.0 108159.0 76246.0 True False 137974.00213264543 113642.25765536388 114145.69646594343 125058.13674258432 93451.83977558282 90566.62254367516 85921.6120379741 84330.31975365666 95976.99445523751 89425.01950859133 1.5429015603333456 1.270810543624717 1.276440274692667 1.39846921398289 1.04503013014836 1.0127660361871562 0.9608229610698531 0.9430282511210947 1.073267805616936 1.0 16.44839090750235 -6.322762206941766 4.556352911925028 0.9963338292891631 1.3587469368096565 0.8397754724446344 0.07838761172156423 0.08517089555024329 3.6225834581403213 0.024780023383707536 0.028691544507861304 4.7559556166421914e-07 6.322762206941766 0.3624131075204934 VTSSVPLPSGSTS(ph)SPGR ddPTM_PC-9_AZD4547_30min_R2 1 VTSSVPLPSGSTSSPGR 17 0 Q15036-2;Q15036 Q15036-2 SNX17 Sorting nexin-17 1 VTSSVPLPS(0.001)GS(0.001)T(0.167)S(0.556)S(0.275)PGR 186.94 2.5695000000000003e-08 19866000.0 21382.0 24192.0 35807.0 42499.0 26666.0 34784.0 29871.0 35856.0 27885.0 35522.0 True False 28181.031226771338 32011.590899655526 35332.17578412183 32701.51215300465 22963.88618866502 32608.950981241698 32529.461132205346 30315.279088911466 29358.944171644205 34278.38559205534 0.8221224757242599 0.9338710194996702 1.030742118506034 0.95399802494152 0.669923212311006 0.9512977469043769 0.9489787972904027 0.8843846804715798 0.8564856151932865 1.0 15.065011544041239 -10.487695220707288 24.385298019413014 0.9999999960987748 0.897900196235181 0.10194472745354555 0.09336046783406811 0.0 0.0 0.09352154349739716 0.02268230600650383 3.253155173029827e-11 10.487695220707288 -0.10209979986359374 VTSSVPLPSGSTS(ph)SPGR ddPTM_PC-9_Lapatinib_30min_R1 1 VTSSVPLPSGSTSSPGR 17 0 Q15036-2;Q15036 Q15036-2 SNX17 Sorting nexin-17 1 VTSSVPLPSGST(0.001)S(0.638)S(0.36)PGR 268.93 1.4276999999999998e-69 14611000.0 29046.0 39300.0 44234.0 45243.0 55465.0 40925.0 39118.0 41199.0 42677.0 41716.0 True False 28631.798713615968 39209.00326458481 40597.25126817783 48570.321146223614 52202.657748385594 39174.733150834545 41143.33863415598 43113.25594434394 37870.26685126681 48926.55501692398 0.5851995650156048 0.8013849176796157 0.8297590389132242 0.9927190076927112 1.06695960364118 0.8006844777296046 0.8409204085577712 0.8811831515509484 0.7740227538637712 1.0 15.578330083841559 -4.701323712498317 1.621571820748596 0.8994823748170577 0.4281562730915784 0.5355324667420207 0.08926631445367995 1.0580324037146034 2.3269480570554864 0.026422548519291027 0.8399982214027462 1.989190092562903e-05 4.701323712498317 -0.47132610172547934 VTSSVPLPSGSTSS(ph)PGR ddPTM_PC-9_AZD4547_30min_R2 3 VTSSVPLPSGSTSSPGR 17 0 Q15036-2;Q15036 Q15036-2 SNX17 Sorting nexin-17 1 VTSSVPLPS(0.024)GS(0.012)T(0.012)S(0.219)S(0.733)PGR;VTSSVPLPS(0.044)GS(0.044)T(0.044)S(0.205)S(0.663)PGR;VTSSVPLPSGST(0.005)S(0.206)S(0.789)PGR 246.49 2.4875999999999994e-47 45778000.0 85437.0 94267.0 110918.0 135166.0 126295.0 119878.0 87176.0 118571.0 96581.0 118052.0 True False 112604.18880000286 124736.96425834282 109447.15484746623 104005.56699388284 108761.11926038568 112382.00970932908 94934.49511771047 100248.57644052117 101686.07448598077 113919.03541223236 0.9884580605210398 1.0949615558713628 0.960745098055088 0.9129779462889919 0.9547229650147403 0.9865077359780889 0.8333505877588973 0.8799984662594563 0.8926170601604476 1.0 16.797649310159585 -5.471823365154111 4.76326059255903 0.9190049748335396 1.0410512801597294 0.4410629764132372 0.05267004138594041 0.18039378495851469 8.840892728297295 0.014387598944689243 0.030051552707626293 3.3742451696183053e-06 5.471823365154111 0.12204630532618976 VTSSVPLPSGSTSS(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VTSSVPLPSGSTSSPGR 17 0 Q15036-2;Q15036 Q15036-2 SNX17 Sorting nexin-17 1 VTSS(0.001)VPLPS(0.025)GS(0.012)T(0.078)S(0.078)S(0.805)PGR;VTSSVPLPSGSTS(0.026)S(0.974)PGR;VTSSVPLPSGSTS(0.038)S(0.962)PGR;VTSSVPLPSGST(0.001)S(0.005)S(0.994)PGR 268.17 1.7335999999999995e-69 47434500.0 137269.0 158627.0 178741.0 174792.0 191974.0 145188.0 175051.0 200983.0 160450.0 130130.0 True False 160505.9305136674 174374.44023067888 183002.86331901696 164998.97092330994 154358.0727968901 137574.08569113357 158468.90202050976 195707.4092090913 162796.27770842248 153721.5388914871 1.0441342941991327 1.1343526840033185 1.1904828993951182 1.073362731814594 1.0041408244413448 0.8949564692313411 1.030882875381399 1.2731293911079193 1.059033619376796 1.0 17.22995979870325 -5.986537759385549 23.597771291855274 1.0483137116272259 1.125425708634964 0.12181302610085043 0.09470225220596981 295.9133146900815 518693.0435769056 0.0295245455605268 0.043758408869283665 1.0314833940440143e-06 5.986537759385549 0.07711199700773808 VTSSVPLPSGSTSS(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 3 VTSSVPLPSGSTSSPGR 17 0 Q15036-2;Q15036 Q15036-2 SNX17 Sorting nexin-17 1 VTSSVPLPSGSTSS(1)PGR;VTSSVPLPSGSTS(0.041)S(0.959)PGR;VTSSVPLPSGSTS(0.025)S(0.975)PGR 278.79 6.489499999999998e-83 49956000.0 74863.0 97480.0 114683.0 107521.0 130842.0 109459.0 105151.0 104012.0 113476.0 95024.0 True False 73795.43989180708 97254.29104915335 105254.20642918187 115428.45301954148 123146.13080526948 104777.69373139164 110595.20427220546 108844.77723447414 100695.1379247452 111448.77178847892 0.6621467308035038 0.8726367234780695 0.9444178230061265 1.0357086145248482 1.1049572716601241 0.9401422021074538 0.99234116713378 0.9766350538259232 0.9035105215502663 1.0 16.766021192026543 -4.739463071245592 1.5889920815331318 0.9932514628916461 0.5160133762762652 0.7895800819838432 0.051702434229354326 0.537461801251489 1.2084106456939374 0.015490856970311075 0.41435811205892825 1.8219519899971035e-05 4.739463071245592 -0.4772380866153809 VTTEIQLPS(ph)QSPVEEQSPASLSSLR ddPTM_PC-9_AZD4547_30min_R2 1 VTTEIQLPSQSPVEEQSPASLSSLR 25 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 VT(0.001)T(0.001)EIQLPS(0.498)QS(0.498)PVEEQS(0.001)PAS(0.002)LSSLR 56.972 0.0029955 10326000.0 46031.0 38020.0 64485.0 81314.0 74413.0 64888.0 54049.0 72560.0 56827.0 59322.0 True False 60667.90049572123 50309.22147837728 63629.886766249496 62568.31358877672 64082.03941187773 60830.54310231173 58859.256293213046 61347.51926292433 59830.759205380156 57245.15483621151 1.0597910105982384 0.8788380714895582 1.1115331410720406 1.0929888087087143 1.11943167234376 1.0626321699427426 1.0281962982128314 1.071663085521393 1.0451672176722469 1.0 15.8048659698843 -5.279967005230145 24.999627767675697 1.070348186751409 0.9693145188513962 0.34516484071244036 0.05330194640436108 716.3073593733661 966524.5702410436 0.013322078970428404 0.027812239196612888 5.248473331007527e-06 5.279967005230145 -0.10103366790001289 VTTEIQLPSQS(ph)PVEEQSPASLSSLR ddPTM_PC-9_AZD4547_30min_R2 1 VTTEIQLPSQSPVEEQSPASLSSLR 25 0 E9PMS6;A0A0A0MTE2;E9PMT2;Q8WWI1-5;H0Y424;Q8WWI1-3;F8WD26;J3KP06;Q8WWI1-4;Q8WWI1-2;Q8WWI1;E9PMP7 E9PMS6;Q8WWI1-3 LMO7 LIM domain only protein 7 1 VTTEIQLPS(0.253)QS(0.746)PVEEQSPASLSSLR 92.416 2.3842e-06 9747800.0 64134.0 58823.0 80254.0 115650.0 100300.0 89928.0 73184.0 102060.0 83028.0 92163.0 True False 84527.27792992946 77836.3844035399 79189.77952296792 88988.67927468845 86375.07630402397 84304.78794391398 79697.23422380607 86288.97210548584 87416.69057497852 88936.40142223379 0.9504238599516569 0.8751915206688481 0.8904090817325419 1.0005878116453855 0.9712004862210504 0.9479221847943814 0.896114897267274 0.9702323314816952 0.98291238657116 1.0 16.440486410556282 -1.522878745280338 0.07217745711242803 1.059850266079551 0.6724327793607933 0.27353931352462024 0.03718541071229168 342.26437449154673 1.8263552902549212 1.6600252869968124 13.408170488158294 0.029999999999999964 1.522878745280338 -0.38741748671875775 VTTHPLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VTTHPLAK 8 0 Q99497;K7ELW0;K7EN27 Q99497 PARK7 Protein deglycase DJ-1 0 ; 81.191 0.015303 12586500.0 259710.0 261340.0 286560.0 327970.0 381600.0 332330.0 313160.0 313580.0 292100.0 263030.0 False True 303673.773493685 287284.10806410934 293392.6771848522 309594.9041930865 306828.21933852026 314902.02976647124 283495.21771793906 305348.8572654745 296371.4099010912 310715.25685566606 0.9773378255279818 0.9245896418841094 0.9442493431249159 0.9963942785625748 0.9874900332977489 1.0134746293219519 0.9123955501471519 0.9827288828862228 0.9538360391448757 1.0 18.245233557382257 -5.7377371480015 24.9902806653103 0.9764603064890016 0.9463119852976992 0.17173997053322632 0.029218759786455505 412.7237787313517 435148.6832280952 0.00794579126254554 0.013752765297535297 1.8292069887574644e-06 5.7377371480015 -0.030148321191302396 VTTHPLAK ddPTM_PC-9_Lapatinib_30min_R1 1 VTTHPLAK 8 0 Q99497;K7ELW0;K7EN27 Q99497 PARK7 Protein deglycase DJ-1 0 93.162 0.0062369999999999995 8252800.0 157930.0 149830.0 160180.0 169760.0 167420.0 155570.0 145220.0 137590.0 165750.0 159280.0 False True 155677.88923918517 149483.0778405278 147010.61871268053 182244.71670275877 157572.68476038438 148916.63375138267 152738.78103308278 143982.9336969898 147081.48957512167 186811.33577274115 0.8333428407608503 0.8001820511704721 0.7869469917581511 0.9755549145286465 0.8434856702276031 0.7971498792372109 0.817609811531415 0.7707398113792584 0.787326363074929 1.0 17.51122247534586 -6.550702075743011 21.35956135405071 0.8193033712547894 0.8496405793899059 0.0 0.07682612408219869 186.2740242742701 142994.59847361228 0.025040136571009453 0.025041877793875712 2.8138304447669376e-07 6.550702075743011 0.030337208135116533 VTVAGLAGKDPVQCSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTVAGLAGKDPVQCSR 16 1 Q99497;K7ELW0 Q99497 PARK7 Protein deglycase DJ-1 0 112.62 0.0025622 0.0 13807.0 9735.4 7740.9 11384.0 11915.0 10143.0 10236.0 9470.0 9936.0 7187.4 False True 16144.252399319623 10701.866172982836 7925.472413526725 10746.191387425968 9580.341282543173 9611.083224268992 9266.371977777568 9221.422534294396 10081.295202934778 8490.418724572903 1.9014671623432489 1.2604638852509806 0.9334607244503602 1.2656845010864335 1.128370884090301 1.1319916644926675 1.0913916354865876 1.086097498066359 1.1873731473051585 1.0 13.051619990026795 -4.781544520487688 3.565943896521664 1.1122098762963326 1.9931750196044409 0.8811638373604216 0.08759952258675703 0.0815085048046835 1.737559999862325 0.020794615409001804 0.193918754529805 1.6536952521248104e-05 4.781544520487688 0.8809651433081083 VTVHST(ph)PVRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTVHSTPVRR 10 1 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 VT(0.001)VHS(0.172)T(0.828)PVRR 66.98899999999999 0.038004 3491800.0 11886.0 9063.0 12787.0 10946.0 12765.0 9104.8 9736.4 11459.0 9149.7 6920.0 True False 13898.065040799092 9962.714744719631 13091.890574967541 10332.731107410807 10263.789884319223 8627.328259915641 8814.09770656834 11158.213391814106 9283.497052968225 8174.541221310142 1.7001645308935927 1.218749098573008 1.601544382801374 1.2640135791932272 1.255579928762563 1.0553899021788689 1.0782375998778921 1.3649956725064711 1.1356597026836388 1.0 12.996922049362885 -1.522878745281154 0.2707716987215808 1.0833603533246445 4.811906734322832 0.5490769120198142 0.1472073069681372 42.80903949862365 0.5983061132543399 0.1715311837912603 74.66180506168135 0.029999999999943596 1.522878745281154 3.728546380998188 VTVHST(ph)PVRR ddPTM_PC-9_Lapatinib_30min_R1 1 VTVHSTPVRR 10 1 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 VT(0.003)VHS(0.259)T(0.738)PVRR 76.357 0.019735 2662400.0 14948.0 12161.0 16674.0 12427.0 12126.0 9905.4 9830.8 8133.9 13136.0 8920.8 True False 14734.838778872529 12132.841951669609 15303.128083501322 13340.923035256743 11412.77252063326 9481.76913261519 10339.790721526173 8511.830688261833 11656.48535178764 10462.748393781176 1.40831435721331 1.1596228347497202 1.4626298471056765 1.275087819485967 1.090800628199829 0.9062407673160661 0.9882480522681701 0.8135367847821969 1.1140940136452095 1.0 13.352974253433544 -6.376658900822955 2.586529415173287 0.9553215866269082 1.330011167245432 0.7337832047595503 0.10298152550639535 0.14016320331092902 1.8279747657107412 0.0329846204830437 0.0386119285763853 4.200887963463644e-07 6.376658900822955 0.37468958061852375 VTVLFAGQHIAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTVLFAGQHIAK 12 0 Q60FE5;P21333-2;P21333;A0A087WWY3;F8WE98 Q60FE5 FLNA Filamin-A 0 81.92 0.010641 2556100.0 12350.0 11858.0 12679.0 16673.0 18976.0 15627.0 14830.0 16028.0 15460.0 12583.0 False True 14440.611076381369 13035.183873208127 12981.315445375269 15738.86586459532 15257.789020355785 14807.492610238738 13425.195040097815 15607.28198306977 15686.073252553502 14864.198293026808 0.9715028548264083 0.8769516940125375 0.8733276554488075 1.058843911681321 1.0264791090356769 0.9961850829980738 0.9031899854562578 1.0499915081455529 1.0552922494254036 1.0 13.859554032511436 -5.755583319271636 24.999046345654385 1.0102413026735892 0.9042298188656586 0.4907176776207044 0.04921657428660601 125.73268537798035 536735.500372963 0.014186332054162717 0.023752823246340534 1.7555640574288879e-06 5.755583319271636 -0.10601148380793068 VTVPSDIT(ph)TAFS(ph)S(ph)VDRLHT(ph)T(ph)SAFK ddPTM_PC-9_AZD4547_30min_R2 1 VTVPSDITTAFSSVDRLHTTSAFK 24 1 E9PF17;P13611-3;P13611-5;P13611 E9PF17 VCAN Versican core protein 5 VT(0.035)VPS(0.164)DIT(0.52)T(0.515)AFS(0.829)S(0.937)VDRLHT(0.667)T(0.667)S(0.667)AFK 42.638999999999996 0.023625999999999998 2627500.0 3233.3 4079.7 5224.1 6542.8 6331.7 4715.9 4760.8 8370.7 4994.3 5133.9 True False 4261.422143182105 5398.383242118249 5154.825020633697 5034.45854525233 5452.652748097589 4421.014027496487 5184.501977108339 7077.200654550177 5258.288501934472 4954.163723637544 0.8601698249998891 1.0896658938341548 1.0405035659275346 1.0162075430070427 1.1006202160985579 0.8923835129635972 1.0464938718863477 1.4285358840248048 1.0613877124903792 1.0 12.274425831764113 -7.54613701674099 24.99379742780655 1.1944801268501908 1.0076885367004067 0.23658357538650665 0.12723254713281515 272.7102834154369 293056.1983847336 0.05593703746144117 0.03229753968233329 2.8435638422657765e-08 7.54613701674099 -0.18679159014978408 VTVPTSGNTIES(ph)PLHENISNSTSFKDEK ddPTM_PC-9_AZD4547_30min_R2 2 VTVPTSGNTIESPLHENISNSTSFKDEK 28 1 A0A2R8YFF1;Q8N302 A0A2R8YFF1 AGGF1 Angiogenic factor with G patch and FHA domains 1 1 VTVPTSGNTIES(0.999)PLHENISNSTSFKDEK;VTVPT(0.001)S(0.001)GNTIES(0.995)PLHENIS(0.003)NSTSFKDEK 99.387 4.2147000000000004e-10 21187100.0 55380.0 53656.0 76629.0 92394.0 96133.0 94878.0 74546.0 85256.0 84390.0 82577.0 True False 72989.68802444098 70999.25269973205 75612.84939150087 71093.99077307018 82786.59232636818 88945.26366140322 81180.44958526247 72081.6441879808 88850.68311440047 79686.00436448246 0.9159662177386554 0.8909877370056434 0.948884939011987 0.8921766292596056 1.038910069423279 1.1161968073410866 1.018754174371003 0.904570943954983 1.1150098919252986 1.0 16.282038738558036 -6.265317947120043 24.883090436481375 1.0309923833549794 0.9131370869682188 0.5072535808051937 0.058043050102629376 278.8859102478569 1789198.804675282 0.0181253150444509 0.021360379530553825 5.428527633099806e-07 6.265317947120043 -0.11785529638676062 VTVPTSGNTIES(ph)PLHENISNSTSFKDEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTVPTSGNTIESPLHENISNSTSFKDEK 28 1 A0A2R8YFF1;Q8N302 A0A2R8YFF1 AGGF1 Angiogenic factor with G patch and FHA domains 1 1 VTVPT(0.005)S(0.005)GNT(0.004)IES(0.981)PLHENIS(0.002)NS(0.001)T(0.001)S(0.001)FKDEK 52.36600000000001 0.0039443 6258000.0 10206.0 11474.0 13851.0 16974.0 19946.0 18083.0 14574.0 12970.0 13730.0 12080.0 True False 11933.6742223116 12613.062890975727 14181.260370210026 16023.001810450482 16037.724483559052 17134.695646697844 13193.445213377312 12629.551242850932 13930.775275391956 14270.008374772624 0.8362766095784964 0.8838861589789853 0.9937808022089537 1.1228445975390529 1.1238763189453695 1.200748815045518 0.9245576363291752 0.8850416139333324 0.976227547281585 1.0 13.80069856105124 -5.2618865576681 3.048952797776699 1.0359020331886648 0.8480505777101607 0.36129064589930526 0.09121183968626768 0.3131924676268878 5.879032559053403 0.028202628307839633 0.08268700274220812 5.471588679374186e-06 5.2618865576681 -0.18785145547850413 VTVS(ph)EEEILPATR ddPTM_PC-9_AZD4547_30min_R2 3 VTVSEEEILPATR 13 0 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 VT(0.048)VS(0.952)EEEILPATR;VT(0.184)VS(0.816)EEEILPATR;VT(0.004)VS(0.996)EEEILPATR 148.85 0.0001182 11856430.0 19277.3 22928.699999999997 25480.2 33476.6 27796.6 24923.9 20007.5 26752.7 22198.699999999997 21819.4 True False 25407.08040725092 30339.953879833505 25142.315899533078 25759.087078314198 23937.52189424157 23365.404592955674 21788.12874033673 22618.684930888056 23372.077962455744 21055.50944730848 1.2066713688800677 1.4409508331184955 1.194096773694878 1.2233894004216068 1.1368768803312663 1.109705022879058 1.034794660032408 1.0742406868611483 1.1100219646047742 1.0 14.361910162119573 -6.1274182635362235 0.9393610148554961 1.0588448192908835 1.3223557366033174 0.6843260382923918 0.06648023736786345 0.32499969136224993 0.597199990991477 0.029110146842348535 0.05476948266123121 7.457302090968779e-07 6.1274182635362235 0.2635109173124339 VTVS(ph)EEEILPATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VTVSEEEILPATR 13 0 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 VT(0.004)VS(0.996)EEEILPATR 103.83 0.0014061 1940800.0 3018.4 3531.4 3164.8 4214.5 3886.5 3067.8 3887.7 2461.7 2607.5 2563.7 True False 3529.3555038825516 3881.974053790454 3240.260834570837 3978.375228593354 3124.968224473689 2906.9191674467515 3519.4289114894345 2397.08298338675 2645.629754594647 3028.478515761965 1.1653889851005155 1.281823210429396 1.0699302695088089 1.3136547635677698 1.0318607869296532 0.9598612479228273 1.1621112361115584 0.7915139469905218 0.8735837949073271 1.0 11.564377461509585 -6.8283928466590185 0.8710769260679775 0.9042927142286524 1.21288017683577 0.5134643293088521 0.11164401631330773 0.4680046595001874 0.7644936911744012 0.07210450785452109 0.06285896175272862 1.4845921278295733e-07 6.8283928466590185 0.30858746260711756 VTVS(ph)EEEILPATR ddPTM_PC-9_Lapatinib_30min_R1 1 VTVSEEEILPATR 13 0 A0A0J9YWL0;Q9Y4K1 A0A0J9YWL0 AIM1 Absent in melanoma 1 protein 1 VT(0.063)VS(0.934)EEEILPAT(0.003)R 81.185 0.011918000000000002 1076400.0 11927.0 9669.7 10809.0 8640.4 11499.0 11388.0 11224.0 11488.0 11026.0 8424.7 True False 11756.918792856079 9647.310403754593 9920.325743946609 9275.843839529449 10822.651427903827 10900.961786724594 11805.123800546215 12021.774419005884 9784.13577107266 9880.898169792881 1.1898633697894412 0.9763596626516813 1.0039902824091702 0.9387652498926506 1.095310491205142 1.1032359203994402 1.1947419756471054 1.216668182631203 0.9902071251967726 1.0 13.270426472849682 -6.494172554961618 17.85485626770118 1.118029186794874 1.0213343594759272 0.11757967692002325 0.09145815336687683 34.87830454324177 21692.93275325999 0.02827731184169121 0.031874770849595356 3.204995654663979e-07 6.494172554961618 -0.09669482731894674 VTVT(ph)S(ph)LAGQR ddPTM_PC-9_Lapatinib_30min_R1 1 VTVTSLAGQR 10 0 B5MCJ9;A0A2R8YEA1;O15016-2;O15016 B5MCJ9 TRIM66 Tripartite motif-containing protein 66 2 VTVT(1)S(1)LAGQR 117.4 0.025596 4227500.0 0.0 2151.9 1294.3 2323.9 3112.4 2371.8 3267.4 2858.2 3145.9 1210.1 True False 0.0 2146.917407762343 1187.8876501424825 2494.807358303142 2929.3347512138353 2270.3636429358426 3436.5699844890146 2991.0024063720925 2791.5756142043783 1419.2641726431048 0.0 1.5126975295685263 0.8369743089690426 1.7578174707651826 2.063981327562519 1.5996765695196333 2.4213744352392608 2.107431769239922 1.9669175534852044 1.0 10.470927432968436 -5.1126387232678265 0.8590638963221794 1.9507511817517593 2.4551750151972733e-21 0.5345805094439198 0.47083022866178403 1.1744056488877603 0.9398671187360338 0.17098450216872166 1.968685165780514 7.715450276652522e-06 5.1126387232678265 -1.9507511817517593 VTYTPMAPGSYLISIK ddPTM_PC-9_Lapatinib_30min_R1 1 VTYTPMAPGSYLISIK 16 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 112.51 0.0045278 2997300.0 11368.0 8134.0 14073.0 11307.0 12701.0 8905.2 10875.0 10951.0 10696.0 11605.0 False True 11205.89023536412 8115.16622275147 12915.972263350963 12138.554499046273 11953.952151126752 8524.345355035113 11438.054288216335 11459.823438591 9491.30384612672 13610.908787309509 0.8233021329047645 0.596225156568374 0.9489426801091718 0.8918254239102664 0.8782626008244457 0.6262877437679263 0.8403593372751795 0.8419587271994556 0.6973306481177942 1.0 13.732475776969839 -10.66587801984525 4.703951539138436 1.0000190001073552 0.7958042653545327 0.23764406548059736 0.1107280725940804 2.217871628377453e-05 4.04062276902891e-06 0.10777070068279448 0.026135803263329205 2.1583505392650674e-11 10.66587801984525 -0.20421473475282248 VVACNLYPFVK ddPTM_PC-9_Lapatinib_30min_R1 1 VVACNLYPFVK 11 0 P31939-2;P31939;C9JLK0 P31939-2 ATIC Bifunctional purine biosynthesis protein PURH;Phosphoribosylaminoimidazolecarboxamide formyltransferase;IMP cyclohydrolase 0 100.02 0.019913999999999998 1612500.0 27745.0 23489.0 28434.0 24331.0 22973.0 20366.0 23161.0 21637.0 22256.0 24198.0 False True 27349.35121219016 23434.61266365987 26096.266278414067 26120.382905836632 21621.77330665578 19494.993655464783 24360.163252356644 22642.33400975193 19749.294913930087 28380.592058191753 0.9636638712861546 0.8257267013883779 0.9195109892318705 0.9203607469597261 0.7618506781790301 0.6869128598688893 0.8583387972459632 0.7978104883550681 0.6958732528706942 1.0 14.792617065865025 -6.2591927543772945 24.95464865995419 0.7872710173006294 0.9023589048956852 0.24931712943766549 0.089294955851743 256.47990551737297 2848878.8111648317 0.025657275585060615 0.03156518007109725 5.505632838203662e-07 6.2591927543772945 0.11508788759505573 VVASGPGLEHGK ddPTM_PC-9_Lapatinib_30min_R1 2 VVASGPGLEHGK 12 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 171.49 0.00039332 16232000.0 129791.0 115131.0 143564.0 138266.0 146040.0 126884.0 129854.0 116324.0 136478.0 115256.0 False True 127940.15653924571 114864.42124312778 131760.72209306576 148434.5428818546 137450.2143256869 121457.46710105056 136577.2047394981 121728.83770163999 121106.41046294723 135177.84603103373 0.9464580202725941 0.8497281515845249 0.9747212724695771 1.0980685610849092 1.0168102123341385 0.8985012756688453 1.0103519825885012 0.9005087836189803 0.8959042773558027 1.0 17.04449920564226 -10.3736823426495 24.302993129151297 0.9999999996545813 0.9565249367720675 0.03617541326248197 0.0697019975836465 0.0 0.0 0.07266917791728875 0.017624864487046116 4.229778811621607e-11 10.3736823426495 -0.04347506288251379 VVCRANAEY(ph)MS(ph)PS(ph)GK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVCRANAEYMSPSGK 15 1 O75431-2;O75431;C9JAZ1 O75431-2 MTX2 Metaxin-2 3 VVCRANAEY(1)MS(1)PS(1)GK 53.211000000000006 0.042613 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 470.43 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 458.08171096178614 0.0 0.0 0.0 VVDES(ph)DETENQEEK ddPTM_PC-9_Lapatinib_30min_R1 1 VVDESDETENQEEK 14 0 O75717-2;O75717 O75717-2 WDHD1 WD repeat and HMG-box DNA-binding protein 1 1 VVDES(1)DETENQEEK 139.77 0.00010796 2502500.0 5898.9 6264.1 6780.0 5359.3 6066.9 5642.2 5425.8 8156.4 6112.9 6154.1 True False 5814.780604274224 6249.595861315158 6222.574571556846 5753.44080010071 5710.0568699843225 5400.896258610597 5706.721375356705 8535.37612040212 5424.400830309276 7217.827985177199 0.8056136300581941 0.8658554726088737 0.8621117854755971 0.797115255713518 0.7911045929205723 0.748271678086826 0.7906424740346045 1.1825408056177962 0.7515281385825526 1.0 12.817349046089403 VVDLMAHMASK ddPTM_PC-9_AZD4547_30min_R2 2 VVDLMAHMASK 11 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 122.7 0.00054004 4611000.0 47005.0 40761.0 66370.0 64211.0 60295.0 65973.0 54463.0 78988.0 56202.0 58614.0 False True 61951.61223526266 53936.196125200855 65489.89043461233 49408.14600006073 51924.080017458815 61847.69788079175 59310.10149118874 66782.21956366953 59172.72298134295 56561.9417007131 1.0952879334140966 0.9535775205631044 1.157843745554914 0.8735228055199142 0.9180038459819032 1.0934507554222102 1.0485867300139202 1.1806917788826117 1.0461579147060458 1.0 15.787544026463149 -6.80362456759334 24.996986234698184 1.0834963506152544 0.9988693871925295 0.1453227398773933 0.08831890039578023 258.8738103491238 153394.87311917692 0.031105609908305305 0.027432798548338546 1.571720915049195e-07 6.80362456759334 -0.08462696342272491 VVDLMAHMASK ddPTM_PC-9_Lapatinib_30min_R1 4 VVDLMAHMASK 11 0 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ;;; 147.71 0.00022127 35131100.0 216599.0 229496.0 241575.0 229877.0 240998.0 231993.0 244963.0 236961.0 204366.0 220791.0 False True 213510.2585406086 228964.61611219245 221713.63600646693 246782.92142719147 226822.97146029831 222071.20019209693 257645.9855268358 247971.0731286602 181348.1490106147 258954.43016448544 0.8245090010817304 0.8841888357220081 0.856187846895056 0.9529974878994627 0.8759184823222467 0.8575686465415532 0.9949472011858669 0.9575857534901074 0.7003091196216417 1.0 17.98233871458799 -3.677463928085347 0.8752667247511269 0.9031197351306016 0.4038486985671717 0.071746403149897 0.08307424910451498 38.694522240177186 5.2817173328839955 0.02770568861271721 29.0417542382127 0.0002101532312240983 3.677463928085347 -0.4992710365634299 VVDLMAHMASKE ddPTM_PC-9_AZD4547_30min_R2 6 VVDLMAHMASKE 12 1 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ;;;;; 105.65 0.001117 46956500.0 282545.0 220374.0 452559.0 778120.0 618855.0 429926.0 302868.0 428980.0 331200.0 432724.0 False True 372388.4326989105 291605.58585154964 446557.77196320286 598736.4558341607 532937.6654648727 403042.6592560185 329822.6652669404 362690.9979797314 348706.55584179936 417574.464470935 0.8917892840279996 0.6983319399595295 1.0694087161890744 1.4338435579214766 1.2762697693694043 0.9651994878725925 0.7898535311176758 0.8685660375311965 0.8350763408955311 1.0 18.671673965301636 -6.998073865366903 24.958393522242424 0.864579036608171 1.0775991720199884 0.194675262669866 0.19225637670118004 112.45461211953646 1457133.8262604827 0.0784227444000268 0.06870013870758532 1.0044449384558591e-07 6.998073865366903 0.2130201354118174 VVDLMAHMASKE ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VVDLMAHMASKE 12 1 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ; 80.17 0.0040493000000000005 67324000.0 131341.0 97996.0 137187.0 206176.0 224220.0 218114.0 176729.0 219269.0 212440.0 160614.0 False True 153574.43719700427 107724.39524699796 140458.0583645944 194624.62715161053 180285.7005767376 206675.71787224736 159987.94971284186 213513.4210847091 215546.53310300602 189732.046780276 0.8094280318119113 0.567771217751901 0.7402969648414505 1.0257867896033426 0.9502121736214759 1.089303158741514 0.8432310325420141 1.1253418950989007 1.136057596809806 1.0 17.533603852849858 -5.713909564249506 4.3665890746262885 1.0227890963702146 0.681728278799197 0.690662679029094 0.09788262976745457 0.11064802928244724 4.441094490755805 0.02694551524892708 0.04678419723646226 1.9323706642827042e-06 5.713909564249506 -0.3410608175710177 VVDLMAHMASKE ddPTM_PC-9_Lapatinib_30min_R1 4 VVDLMAHMASKE 12 1 P04406;P04406-2;E7EUT5 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 ;;; 131.69 6.903e-05 33230900.0 346785.0 269748.0 352643.0 312992.0 357002.0 355971.0 265187.0 251730.0 360565.0 250619.0 False True 341839.78230742016 269123.4150792678 323650.05378134514 336010.4757907036 336003.8442529369 340746.95013893023 278917.0852900434 263426.29478554544 319954.3727822251 293938.16022117314 1.1629649653185674 0.9155783477611974 1.1010821240012367 1.1431332207355223 1.143110659739149 1.1592470670787893 0.9488971594575295 0.896196310772752 1.0885091358722396 1.0 18.165153141993784 -7.271365744898753 24.85911520714338 0.9747503380574849 1.099011523574513 0.3447341585212872 0.0810429371342309 777.9625276286638 1948283.5070226921 0.03470031746472882 0.023708017417583417 5.3534562161765236e-08 7.271365744898753 0.12426118551702814 VVDNS(ph)PPPALPPK ddPTM_PC-9_AZD4547_30min_R2 3 VVDNSPPPALPPK 13 0 Q13905-2;Q13905;Q13905-4;Q13905-3 Q13905-2 RAPGEF1 Rap guanine nucleotide exchange factor 1 1 VVDNS(1)PPPALPPK;VVDNS(1)PPPALPPK;VVDNS(1)PPPALPPK 110.55 0.00066419 10497300.0 112556.0 114924.0 144269.0 188548.0 176522.0 143897.0 124398.0 156517.0 116601.0 137773.0 True False 148346.46668976094 152070.93553869115 142355.89879631015 145081.17163756132 152014.96729151465 134899.0978423341 135469.18100914214 132330.8940528548 122764.2908143405 132949.60920483753 1.1158097235261613 1.1438238626515487 1.0707507878190166 1.0912493275104893 1.143402889265382 1.0146633649331978 1.0189513291492467 0.9953462431692487 0.9233896327231443 1.0 17.020520010947386 -7.0991113512888715 1.3904522964689687 0.9713980845219853 1.112503783257673 0.7726592180659965 0.03292691748683517 0.19949600130275752 0.7712623513630342 0.018265737393358475 0.012297080776546355 7.959552446565864e-08 7.0991113512888715 0.14110569873568768 VVDNS(ph)PPPALPPK ddPTM_PC-9_Lapatinib_30min_R1 4 VVDNSPPPALPPK 13 0 Q13905-2;Q13905;Q13905-4;Q13905-3 Q13905-2 RAPGEF1 Rap guanine nucleotide exchange factor 1 1 VVDNS(1)PPPALPPK;VVDNS(1)PPPALPPK;VVDNS(1)PPPALPPK;VVDNS(1)PPPALPPK 135.91 5.3018e-05 9447900.0 183703.0 161015.0 170047.0 146076.0 163621.0 150140.0 140310.0 123728.0 185991.0 118757.0 True False 181083.3615329953 160642.17966023242 156066.39206040205 156818.91633525136 153997.1344712629 143718.8621934342 147574.56525789748 129476.85457127058 165042.73500794242 139283.98921624426 1.3001017744534569 1.1533427536371654 1.1204905383496908 1.1258933436475846 1.1056341460192949 1.0318405080307158 1.0595228215985526 0.9295889304997742 1.1849368756354806 1.0 17.08766990318805 -1.5228787452873387 0.4153104718500928 1.0346068850649477 5.543405118743274 0.5843332962005315 0.06334495698998191 52.65536771271334 0.6805365877600366 0.04167235233921304 196.5574753046586 0.02999999999951638 1.5228787452873387 4.508798233678326 VVDRDSEEAEIIR ddPTM_PC-9_Lapatinib_30min_R1 2 VVDRDSEEAEIIR 13 1 P09874 P09874 PARP1 Poly [ADP-ribose] polymerase 1 0 ; 96.23 0.004298399999999999 7391400.0 80340.0 101928.0 82126.0 86915.0 94304.0 93943.0 97734.0 103421.0 90637.0 77239.0 False True 79194.3368674486 101691.99197843767 75373.91729552779 93307.0190399403 88757.22412879746 89925.27688182904 102794.18830386527 108226.31721692259 80428.50661007737 90589.65823550183 0.8742094672834582 1.1225563045405647 0.8320366669182219 1.029996368872198 0.9797721490245533 0.9926660353222039 1.1347232157189056 1.1946873332447234 0.8878332049889296 1.0 16.46705874037326 -7.086023483829789 6.941007352078838 1.070359156516189 0.9735416379006828 0.12123924737077008 0.1063954089591182 0.48885810221633563 33.794508876562496 0.03900643523707076 0.030242816584849917 8.203071862364439e-08 7.086023483829789 -0.09681751861550614 VVDVEEQQLEES(ph)GPHDLTETSYLPR ddPTM_PC-9_AZD4547_30min_R2 1 VVDVEEQQLEESGPHDLTETSYLPR 25 0 P38398-8;P38398-4;P38398;P38398-7;H0Y8B8;B7ZA85;E7EUM2;A0A2R8Y7V5;P38398-6;P38398-5;P38398-3;K7EPC7 P38398-8 BRCA1 Breast cancer type 1 susceptibility protein 1 VVDVEEQQLEES(0.958)GPHDLT(0.015)ET(0.007)S(0.02)YLPR 67.083 0.00041218 5214500.0 5770.7 4746.5 7783.2 11050.0 7312.7 11003.0 9025.1 7791.6 7856.0 9350.4 True False 7605.66256198341 6280.713302133556 7679.989682547462 8502.59322079817 6297.457831390183 10314.980670612995 9828.316416064623 6587.587253156028 8271.252121658126 9023.045342040257 0.8429152546255128 0.6960746692550017 0.851152730748762 0.942319682378499 0.6979304206805886 1.143181739601079 1.0892460409427889 0.7300846890864086 0.9166807666498838 1.0 13.139398720177901 -6.746023724885199 24.99993817697462 0.9660569572556805 0.8100403275888718 0.32038300682000265 0.1231452501379583 347.8004509618531 564035.2500087809 0.043212343758234635 0.04306166272854195 1.794635585784305e-07 6.746023724885199 -0.15601662966680874 VVDVEEQQLEES(ph)GPHDLTETSYLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVDVEEQQLEESGPHDLTETSYLPR 25 0 P38398-8;P38398-4;P38398;P38398-7;H0Y8B8;B7ZA85;E7EUM2;A0A2R8Y7V5;P38398-6;P38398-5;P38398-3;K7EPC7 P38398-8 BRCA1 Breast cancer type 1 susceptibility protein 1 VVDVEEQQLEES(1)GPHDLTETSYLPR 111.18 1.1830999999999999e-07 3813800.0 15603.0 18264.0 22549.0 26130.0 24596.0 23013.0 26746.0 22056.0 21436.0 17189.0 True False 18244.27972670271 20077.129217429025 23086.653677558716 24666.02081460299 19776.590363863343 21806.157767928853 24212.42525572869 21477.053370263715 21749.46094707225 20305.229631950868 0.8985015218933947 0.9887664203431159 1.1369806742412407 1.2147619732302999 0.9739653637181381 1.0739183039632427 1.1924231192948311 1.0577104400961292 1.0711260764492336 1.0 14.309563722349903 -5.018299061316352 3.5519718066793526 1.0950739330322428 0.9069156035832452 0.4201867154152831 0.07219266074266747 0.21295992628643035 5.566429595997898 0.018875108911523684 0.07801372236025313 9.587402021023837e-06 5.018299061316352 -0.18815832944899757 VVDVEEQQLEES(ph)GPHDLTETSYLPR ddPTM_PC-9_Lapatinib_30min_R1 1 VVDVEEQQLEESGPHDLTETSYLPR 25 0 P38398-8;P38398-4;P38398;P38398-7;H0Y8B8;B7ZA85;E7EUM2;A0A2R8Y7V5;P38398-6;P38398-5;P38398-3;K7EPC7 P38398-8 BRCA1 Breast cancer type 1 susceptibility protein 1 VVDVEEQQLEES(0.964)GPHDLT(0.006)ET(0.006)S(0.017)Y(0.007)LPR 46.968 0.022513 3498600.0 10384.0 8920.2 11289.0 11482.0 12447.0 12947.0 9290.6 8591.5 13406.0 10420.0 True False 10235.922255807624 8899.54582495545 10360.861996800191 12326.424582829162 11714.891931743543 12393.286990931088 9771.62180874507 8990.69245481277 11896.075108561596 12221.083116222753 0.8375626086872817 0.7282125275084529 0.84778590393897 1.0086196506156295 0.9585804973531952 1.0140907211800028 0.7995708494751852 0.7356706741383803 0.9734059571831462 1.0 13.577084531903864 -5.5242696904624475 24.94263505200192 0.9166974453042569 0.7841654658566004 0.28994999538291666 0.09072806649762402 58.816056260651855 1054695.6745238146 0.02644949519563829 0.04627335757205754 2.9904070612621354e-06 5.5242696904624475 -0.1325319794476565 VVDYSQFQES(ph)DDADEDYGR ddPTM_PC-9_AZD4547_30min_R2 18 VVDYSQFQESDDADEDYGR 19 0 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(0.998)DDADEDY(0.002)GR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR 281.65 4.680199999999999e-137 137700300.0 277698.5 371921.0 416273.89999999997 416488.89999999997 393324.89999999997 450013.5 388104.99999999994 521109.39999999997 411237.8 363807.39999999997 True False 366000.84651237336 492137.1899384425 410753.8360974658 320473.8187943602 338718.52691697545 421874.084705525 422645.59314099094 440583.91613273177 432974.9905493922 351070.61366035446 1.0425277202678753 1.401818240516604 1.170003469714649 0.9128471775322234 0.9648159479524848 1.2016787173012147 1.203876304924462 1.2549723588057915 1.233298868381723 1.0 18.42140171502807 VVDYSQFQES(ph)DDADEDYGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 13 VVDYSQFQESDDADEDYGR 19 0 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR 243.16 1.4747e-53 49522600.0 162968.07 231775.09000000003 225746.42999999996 208689.4 234506.81999999998 160378.24 204790.76 161903.99 146393.37 145223.41999999998 True False 190555.34548489848 254784.18918699346 231129.0810393032 196997.20949816323 188556.89204229292 151967.7227646444 185391.49665609287 157654.18181395746 148534.0960872037 171551.27645804017 1.1107777768794773 1.4851780438329252 1.3472886113781566 1.148328438968782 1.099128470130691 0.8858443137367985 1.080676870984623 0.9189915987160736 0.8658291512248453 1.0 17.388280335003515 -6.195562556946387 1.6382928442906235 0.9542482113551066 1.329921365503374 0.6729573474125146 0.10782055036558903 0.20999959611438707 1.118574767636527 0.03760256338317681 0.053455700088889474 6.374372562432144e-07 6.195562556946387 0.3756731541482673 VVDYSQFQES(ph)DDADEDYGR ddPTM_PC-9_Lapatinib_30min_R1 12 VVDYSQFQESDDADEDYGR 19 0 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR 283.49 9.271799999999996e-203 151930500.0 269951.19999999995 460399.4 473270.0 406184.5 513596.3 509466.4 483953.4 535152.2 500809.6 450995.4 True False 266101.6463850123 459333.3734761545 434359.5674750313 436056.66312177153 483387.57540317567 487677.7096961841 509010.1390498276 560017.3248811568 444403.14908911556 528949.3539764036 0.5030758509951466 0.8683881925993341 0.8211742092313966 0.8243826367187963 0.9138636275274468 0.9219742987301944 0.9623041132829032 1.058735246902559 0.8401620036933448 1.0 19.012770067730777 -4.2289884025918765 0.7093009679116229 0.9491242893012714 4.131496322805704e-36 0.7209933082291462 0.07574583155752322 3.312075989594004 0.723616287503065 0.03055823627399874 3.014031099303367 5.902168411231794e-05 4.2289884025918765 -0.9491242893012714 VVDYSQFQES(ph)DDADEDYGRDSGPPTK ddPTM_PC-9_AZD4547_30min_R2 1 VVDYSQFQESDDADEDYGRDSGPPTK 26 1 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 VVDY(0.002)S(0.01)QFQES(0.969)DDADEDY(0.016)GRDS(0.002)GPPTK 75.524 3.6144e-05 20944000.0 41736.0 27156.0 45440.0 62192.0 49410.0 48428.0 33748.0 50921.0 33802.0 39495.0 True False 55007.179837270975 35933.64593547643 44837.43591003145 47854.595256821674 42550.27437868214 45399.78950435757 36751.506621461165 43052.32949817212 35588.70471184929 38112.29207134241 1.443292356552658 0.9428361293047458 1.176456032245456 1.255621025553715 1.1164449070402869 1.19121120869282 0.9642953657225866 1.1296179567889135 0.9337854738631511 1.0 15.217968753916347 -7.252755161311188 24.56798300070736 1.0177261946672376 1.1758610559733649 0.3269463468819567 0.12596940861307185 664.3472906205985 1879465.6418636683 0.0462424820181012 0.03525131471179957 5.5878512772858415e-08 7.252755161311188 0.1581348613061273 VVDYSQFQES(ph)DDADEDYGRDSGPPTK ddPTM_PC-9_Lapatinib_30min_R1 4 VVDYSQFQESDDADEDYGRDSGPPTK 26 1 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 VVDY(0.001)S(0.01)QFQES(0.989)DDADEDYGRDSGPPTK;VVDYS(0.001)QFQES(0.995)DDADEDY(0.003)GRDSGPPTK;VVDYS(0.001)QFQES(0.999)DDADEDYGRDSGPPTK;VVDY(0.001)S(0.04)QFQES(0.951)DDADEDY(0.005)GRDS(0.003)GPPTK 114.92 5.572e-12 130470600.0 263973.0 252699.0 296572.0 247146.0 283724.0 289628.0 229189.0 242863.0 288939.0 212571.0 True False 260208.69661328103 252113.89099128052 272188.9949610258 265321.9412948871 267035.91214284615 277241.2855958441 241055.28498961029 254147.3015949713 256395.647157443 249313.61411694714 1.0437003110918093 1.0112319452920844 1.091753436430264 1.0642095989608928 1.0710843573010254 1.112018236861292 0.9668757393911788 1.0193879804564414 1.0284061224076348 1.0 17.92760213978822 -7.2667876639796924 24.99945619534713 1.0052831274940972 1.064557863365195 0.518507202426143 0.02924064869128657 417.6517043444955 1952218.1488197707 0.012560213669243096 0.00874931889664144 5.410187741409182e-08 7.2667876639796924 0.05927473587109788 VVDYSQFQES(ph)DDADEDYGRDSGPPTKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVDYSQFQESDDADEDYGRDSGPPTKK 27 2 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 VVDY(0.013)S(0.148)QFQES(0.833)DDADEDY(0.005)GRDS(0.001)GPPT(0.001)KK 42.254 0.020446000000000002 7241900.0 10915.0 6268.6 8543.4 13275.0 13704.0 22781.0 15036.0 20288.0 19616.0 12998.0 True False 12762.693918923283 6890.905180265854 8747.10705702493 12531.244788130685 11018.79957498713 21586.3242563415 13611.681228786969 19755.461496912863 19902.84689017396 15354.43450788862 0.8312057283754877 0.44878925216852017 0.5696795315080438 0.8161319638110105 0.7176297876242868 1.4058690500943642 0.8864983742510165 1.286629050829787 1.2962279320640895 1.0 13.906367759483699 -6.668868192988409 6.842704283550559 1.1737315322937316 0.6602328437210992 0.6728347675258671 0.1738305099885942 0.1298666053061269 8.114638170526908 0.05713511164120328 0.056962693140996674 2.143541060390091e-07 6.668868192988409 -0.5134986885726324 VVDYSQFQES(ph)DDADEDYGRDSGPPTKK ddPTM_PC-9_Lapatinib_30min_R1 2 VVDYSQFQESDDADEDYGRDSGPPTKK 27 2 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 VVDY(0.006)S(0.079)QFQES(0.898)DDADEDY(0.006)GRDS(0.005)GPPT(0.006)KK;VVDYS(0.002)QFQES(0.939)DDADEDY(0.047)GRDS(0.01)GPPT(0.002)KK 69.704 7.2639e-05 79827000.0 246854.0 107718.0 138742.0 123656.0 92538.0 105592.0 72155.3 61445.5 127223.0 69067.2 True False 243333.8166925208 107468.58558917415 127335.16831960749 132750.07474432347 87095.09677670797 101076.07630697418 75891.14837540555 64300.48224782608 112893.80602241756 81005.37349374083 3.0039219152705083 1.3266846500927263 1.5719348337977417 1.6387810958563247 1.0751767817407532 1.247770017562899 0.9368656065917597 0.7937804552286212 1.393658237143252 1.0 16.305729991937348 -2.3244589148703008 0.9329713989441942 1.137484331666867 199.999999274896 0.8001601950013223 0.2657966845966633 89.32944445222746 0.9179130663093557 0.08969422530404525 36964.65083965232 0.00473741122915933 2.3244589148703008 198.86251494322914 up VVDYSQFQESDDADEDY(ph)GRDSGPPTK ddPTM_PC-9_AZD4547_30min_R2 1 VVDYSQFQESDDADEDYGRDSGPPTK 26 1 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 VVDYS(0.001)QFQES(0.199)DDADEDY(0.51)GRDS(0.289)GPPT(0.001)K 84.12700000000001 6.9273000000000006e-06 18170000.0 21920.0 28050.0 31150.0 42315.0 35610.0 34350.0 26882.0 44363.0 26043.0 34996.0 True False 28890.104035676155 37116.61395235357 30736.93064695155 32559.930510232953 30666.16617334288 32202.089069849728 29274.445922665604 37507.717710324076 27419.579812161737 33770.80069195338 0.8554758384085291 1.099074146654669 0.9101629223222796 0.9641444633556189 0.9080674886293044 0.9535482846138904 0.8668567319353156 1.1106552685101452 0.8119315873578041 1.0 15.043488765013175 -11.23316536238833 3.678349645874247 1.004419070330465 0.9485958676873635 0.02966157320709273 0.09290997771023995 0.003328869015790711 0.0002621874171014106 0.0889399397799916 0.01988782811920534 5.845674612903498e-12 11.23316536238833 -0.05582320264310148 VVEHNIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVEHNIR 7 0 O00232-2;O00232 O00232-2 PSMD12 26S proteasome non-ATPase regulatory subunit 12 0 107.43 0.008316200000000001 667890.0 3128.0 5727.4 7369.4 6450.0 6140.3 6755.4 5544.6 6779.7 5399.7 4710.2 False True 3657.5086191838805 6295.978420932048 7545.114444605129 6088.627411182143 4937.152293512364 6401.134931797961 5019.375348572242 6601.740058685927 5478.660397271226 5564.121974077316 0.6573379656707464 1.1315313449748905 1.356029662857331 1.0942656252951402 0.8873192062492626 1.1504303754698773 0.9020965701249912 1.1864837056848805 0.9846405996841467 1.0 12.441938330974242 -4.757457814124695 24.999307464239546 1.082969277444402 0.6573373503958369 0.4679076452816545 0.1341120594006979 107.52804454736854 675050.065871505 0.03403488457756274 0.25274733968173724 1.748003049188206e-05 4.757457814124695 -0.4256319270485651 VVEHNIR ddPTM_PC-9_Lapatinib_30min_R1 1 VVEHNIR 7 0 O00232-2;O00232 O00232-2 PSMD12 26S proteasome non-ATPase regulatory subunit 12 0 135.87 4.1175e-09 0.0 7532.2 5973.5 7230.2 7614.2 7925.4 9450.4 9267.8 10745.0 9389.3 9231.4 False True 7424.789446763687 5959.668727760743 6635.760865379102 8174.173668226596 7459.243553935905 9046.228421958387 9747.641336306328 11244.25192655103 8331.778160287728 10827.035189932698 0.6857638602364089 0.550443276780168 0.6128880851471907 0.7549780272098117 0.6889460894032868 0.8355222148321677 0.9003056852876933 1.038534716965386 0.7695345968797501 1.0 13.402350617660495 -6.703611521862273 0.987891168633127 0.942773092961574 0.6161006354331692 0.7197214870075916 0.08049689077051861 0.27229757047704095 0.5735489622208023 0.04401280270238936 0.04262694019777625 1.9787388384608106e-07 6.703611521862273 -0.3266724575284048 VVELRPPS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 VVELRPPSR 9 1 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 VVELRPPS(1)R 57.175 0.039474 2906400.0 23593.0 21345.0 26807.0 23474.0 22724.0 27220.0 23957.0 24327.0 22751.0 18226.0 True False 23256.559493573688 21295.57696393288 24603.031938012453 25200.356266968436 21387.418997102926 26055.864052919165 25197.37623749873 25457.32123007976 20188.542801349002 21376.33981538157 1.0879579803853598 0.9962218578041796 1.1509468950483788 1.1788901413718758 1.0005182918037907 1.2189113888510696 1.1787507335267797 1.190911140538741 0.9444340320049611 1.0 14.38372722688971 -5.2682228919097405 24.72928243174124 1.1199310556369255 1.042089919339383 0.0627125525070058 0.09294246778202561 968.6693146315866 3531292.610308109 0.023634753949148258 0.05096364491638327 5.3923380182133164e-06 5.2682228919097405 -0.07784113629754241 VVEVGSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVEVGSK 7 0 P14618;P14618-2;H3BTN5;P14618-3;B4DNK4;H3BQ34 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 111.82 0.042673 4641100.0 38881.0 39622.0 36149.0 38296.0 47606.0 37961.0 42863.0 47052.0 41684.0 28011.0 False True 45462.78536524567 43555.41030732439 37010.92925584594 36150.39927730719 38277.94604253044 35970.2583334788 38802.70633875338 45816.934855714884 42293.54964161966 33089.172565045985 1.373947483149538 1.3163040031207822 1.1185208449407629 1.092514453368198 1.156811823181268 1.0870703479444594 1.1726707962393395 1.3846503645761747 1.2781688499003687 1.0 15.014071595308994 -5.121439503722466 4.54009731134245 1.1705897460548245 1.361337064654131 0.3463492213720062 0.1014675870427987 0.26946134732717814 8.561566112730201 0.028136520313769696 0.08342990401842622 7.5606737154573435e-06 5.121439503722466 0.1907473185993065 VVFEQTK ddPTM_PC-9_Lapatinib_30min_R1 1 VVFEQTK 7 0 P60174;P60174-3;P60174-4;U3KPZ0;U3KQF3 P60174 TPI1 Triosephosphate isomerase 0 110.81 0.043358 23052000.0 175050.0 184770.0 162250.0 206840.0 178070.0 183790.0 166210.0 143780.0 149520.0 173370.0 False True 172553.75489976126 184342.17641723467 148910.43130311157 222051.70359801254 167596.27269909013 175929.7301354157 174815.5405282242 150460.5436946961 132679.48308459876 203336.773498996 0.8486106665827137 0.9065855292434101 0.73233399321076 1.0920390826360238 0.8242300190718708 0.8652135425778475 0.8597340142661769 0.7399573677972175 0.6525110082227891 1.0 17.633511624922114 -7.65469648618103 5.482671618997274 0.772863441616615 0.878611596425849 0.07436429072017303 0.11790672468866135 0.4100974253847285 18.205290626257472 0.05482906941974724 0.03083830687640135 2.2146419077067127e-08 7.65469648618103 0.10574815480923394 VVFPPGS(ph)PIPLRR ddPTM_PC-9_AZD4547_30min_R2 3 VVFPPGSPIPLRR 13 1 A0A1B0GTU4;A0A1B0GV30 A0A1B0GTU4 1 VVFPPGS(1)PIPLRR;VVFPPGS(1)PIPLRR;VVFPPGS(1)PIPLRR 97.223 0.0014053 15069900.0 25373.7 25430.5 38584.6 46807.0 46848.4 37834.7 38915.4 50201.2 37245.9 42015.4 True False 33442.008794253474 33650.411804468036 38072.942993270226 36016.369310941154 40344.30832224757 35468.89022797797 42378.79521088091 42443.75804881363 39214.642234988096 40544.45363449248 0.8248232691882491 0.829963380634646 0.939041954702291 0.8883180332291088 0.9950635587779967 0.8748148525499784 1.0452427252547287 1.046844987268625 0.967201151321643 1.0 15.307216950926806 -5.154892131623595 0.4155381849892734 1.018069665735473 0.711570439119138 0.633167068313691 0.04774632213776879 2.5835791626918994 0.4417653870498329 0.03956636301567342 0.381733868260707 7.0001584162737215e-06 5.154892131623595 -0.3064992266163351 VVFPPGS(ph)PIPLRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VVFPPGSPIPLRR 13 1 A0A1B0GTU4;A0A1B0GV30 A0A1B0GTU4 1 VVFPPGS(1)PIPLRR;VVFPPGS(1)PIPLRR 81.632 0.005234 11918700.0 13010.400000000001 13199.8 18723.8 22497.0 22862.0 17980.5 20773.8 21906.9 19661.7 14876.2 True False 15212.803752886808 14510.188909560857 19170.246402406916 21236.566026258082 18382.355216240194 17037.570927138782 18805.955274712353 21331.867087279206 19949.21516621806 17573.137300065588 0.8656851359620362 0.8257028134359765 1.0908835499928273 1.2084675413182382 1.0460485741593555 0.9695235765941005 1.070153550478557 1.213890651568493 1.1352107950663768 1.0 14.10108415559683 -5.265176572840592 24.06747858937283 1.096807820064912 0.8456939533230001 0.627699112216551 0.07572677689989113 114.05705421055805 734536.0709813422 0.02117212569764075 0.047045818783491636 5.430295049314871e-06 5.265176572840592 -0.25111386674191194 VVFPPGS(ph)PIPLRR ddPTM_PC-9_Lapatinib_30min_R1 2 VVFPPGSPIPLRR 13 1 A0A1B0GTU4;A0A1B0GV30 A0A1B0GTU4 1 VVFPPGS(1)PIPLRR;VVFPPGS(1)PIPLRR 103.66 0.00066133 12817500.0 19549.1 16063.9 19862.3 16344.699999999999 19424.3 18096.8 12537.6 13371.6 16942.6 12515.9 True False 19270.32624913412 16026.70502651307 18229.29836469523 17546.743762320828 18281.800863643133 17322.842049701227 13186.73558105205 13992.89335142576 15034.34597451257 14679.256638611556 1.3127589988750827 1.091792685493164 1.2418407017114088 1.1953428020439933 1.245417347330493 1.1800898694104252 0.8983244796174722 0.9532426399998744 1.0241898717791338 1.0 13.841491291126852 -7.1875039495992565 5.861397170360524 0.9655292831851864 1.2099174956880183 0.7931735113382131 0.06067825704646465 0.0959565232766395 5.865310302910913 0.022492555742088884 0.017274777286468382 6.493757259392445e-08 7.1875039495992565 0.24438821250283194 VVFRDPYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVFRDPYR 8 1 E9PKU4;P62917;E9PKZ0;G3V1A1 E9PKU4 RPL8 60S ribosomal protein L8 0 74.255 0.036352999999999996 18244000.0 12310.0 9913.0 13991.0 16376.0 20708.0 14411.0 15761.0 18979.0 19079.0 10191.0 False True 14393.83986641737 10897.097127265326 14324.598501162975 15458.505811708334 16650.416053621808 13655.261790884391 14268.003980241527 18480.821359912705 19357.994281078154 12038.547628088381 1.1956458794774887 0.9051837035424589 1.189894241705766 1.2840839517584741 1.3830917622299388 1.1342947847815037 1.1851931330114416 1.535137122088813 1.6080008053390107 1.0 13.555373730439154 -5.579641176022515 3.27912002607592 1.3180254230801527 1.047838928043111 0.23152098690908918 0.18247040274924964 0.32864036871172997 7.1610666064646145 0.05233614618223165 0.10327626350231482 2.6324420771423562e-06 5.579641176022515 -0.2701864950370416 VVFRDPYR ddPTM_PC-9_Lapatinib_30min_R1 1 VVFRDPYR 8 1 E9PKU4;P62917;E9PKZ0;G3V1A1 E9PKU4 RPL8 60S ribosomal protein L8 0 84.916 0.017652 22568000.0 30326.0 23673.0 28231.0 22074.0 32794.0 17274.0 19483.0 16150.0 19004.0 22941.0 False True 29893.545678892715 23618.186622964782 25909.95615481141 23697.395596705363 30865.12139548467 16535.231287660754 20491.734408948858 16900.387958473624 16863.569399008247 26906.321283038957 1.1110231445031034 0.877793228383587 0.962969106116501 0.8807371081101147 1.1471327154240605 0.6145481990540317 0.7615955445334815 0.6281196073105388 0.6267512091903326 1.0 14.715657534202506 -6.771177900150212 24.993997167446004 0.7051724098424367 0.9811369734141056 0.5037452301437373 0.13263556650400607 159.54272936277962 409465.3964457487 0.04385808395338183 0.03915141707647038 1.693643890590724e-07 6.771177900150212 0.2759645635716689 VVFVFGPDKK ddPTM_PC-9_Lapatinib_30min_R1 2 VVFVFGPDKK 10 1 P30041 P30041 PRDX6 Peroxiredoxin-6 0 ; 96.14299999999999 0.014275999999999999 0.0 33988.0 34004.0 34947.0 33756.0 36149.0 29681.0 35936.0 30682.0 30365.0 30626.0 False True 33503.32488736414 33925.26582719952 32073.792559321108 36238.52884671495 34022.78689166847 28411.612819790338 37796.59024380158 32107.597730147834 26944.973942374512 35919.663293420155 0.9327293692505564 0.9444761647700084 0.8929313255894705 1.0088771865896975 0.9471911419030712 0.7909765909469102 1.0522534672735988 0.8938724583208824 0.7501455044905823 1.0 15.13248620604305 VVGAQSLK ddPTM_PC-9_Lapatinib_30min_R1 2 VVGAQSLK 8 0 P52209-2;P52209;K7EMN2;K7EM49;K7EPF6 P52209-2 PGD 6-phosphogluconate dehydrogenase, decarboxylating 0 ; 103.56 0.018125 43342000.0 299610.0 320400.0 278110.0 292440.0 277470.0 278920.0 274030.0 215370.0 240290.0 280440.0 False True 295337.50645825564 319658.133485318 255244.86933564566 313947.0131512423 261149.760127009 266991.2417942766 288217.93256091257 225376.87644683992 213226.00983412404 328913.68033718946 0.8979179770068766 0.9718602557291535 0.776023876762981 0.9544966716781013 0.793976583337271 0.8117365064310113 0.8762722555822026 0.6852158785727378 0.6482734607314997 1.0 18.32734948912934 -6.435873371767899 0.8842809217365261 0.7747617384978185 0.9103734191680259 0.13537181753337935 0.10539351650031366 1.0145830767163726 1.733283957190956 0.05635621488242303 0.0751222187859304 3.665444332645481e-07 6.435873371767899 0.13561168067020746 VVGAVGSDEK ddPTM_PC-9_Lapatinib_30min_R1 1 VVGAVGSDEK 10 0 F2Z3J9;Q14914-2;Q14914 F2Z3J9 PTGR1 Prostaglandin reductase 1 0 96.66799999999999 0.025074000000000003 6952800.0 49862.0 52479.0 48367.0 48386.0 45611.0 46605.0 46471.0 42172.0 43986.0 45629.0 False True 49150.95873642905 52357.48809980015 44390.451962019215 51944.46785096427 42928.2506546762 44611.81279156127 48877.04099565068 44131.46507645511 39031.83348688572 53515.91185317925 0.9184363497584525 0.9783536575709066 0.8294813715181438 0.9706359483040067 0.8021586322297887 0.8336177268912778 0.9133179143007916 0.8246419344872542 0.7293500593612129 1.0 15.70768029047623 -5.757148998863619 0.997647696071161 0.8462874522082796 0.9440685576874224 0.12185802926581846 0.0791820250453251 1.2338380065141241 2.308153305665528 0.030370861974528308 0.09235573875990642 1.7492464497108313e-06 5.757148998863619 0.09778110547914276 VVGQT(ph)TPESFEK ddPTM_PC-9_Lapatinib_30min_R1 1 VVGQTTPESFEK 12 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 VVGQT(0.949)T(0.048)PES(0.004)FEK 126.5 0.0011595000000000002 0.0 25453.0 39046.0 40942.0 23797.0 34341.0 25614.0 30474.0 31505.0 30381.0 27462.0 True False 25090.035552491463 38955.591385979074 37575.906800690354 25547.110764464873 32321.129897003684 24518.5489291503 32051.794609572826 32968.83731465708 26959.171853887045 32208.770109185138 0.7789814844664439 1.2094715586445168 1.1666358781571309 0.7931725017087652 1.0034884842680318 0.7612382852879632 0.9951263118995175 1.0235981443220394 0.8370133899089478 1.0 14.975165952059811 -5.755502662704925 24.997618207938107 0.9176817742180572 1.0674738082900055 0.16506739039468055 0.1382258660589415 233.86627994562582 984722.9750741617 0.03678318966332159 0.061617979201577286 1.7558901286199804e-06 5.755502662704925 0.1497920340719483 VVGQTT(ph)PESFEK ddPTM_PC-9_Lapatinib_30min_R1 1 VVGQTTPESFEK 12 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 VVGQT(0.003)T(0.88)PES(0.118)FEK 145.83 0.00028159 6821600.0 35700.0 38103.0 35917.0 36394.0 49977.0 43630.0 36351.0 44441.0 42154.0 36006.0 True False 35190.9114534218 38014.77484454133 32964.04290362941 39070.536166824975 47037.451118562436 41764.04660649754 38233.076913191 46505.89109984685 37406.172618701 42229.58912502076 0.8333235577840707 0.9001928655284459 0.7805911349513563 0.9251933768798128 1.1138505510746979 0.988975916456469 0.9053622757257221 1.101263167921575 0.8857811168363484 1.0 15.365966589980669 -5.998830080448414 18.07167028008948 1.0009248575309024 0.8456900944680928 0.49720069844950054 0.07260528031461318 0.9814546536502087 15106.909003269911 0.019722656630679607 0.028715928113194563 1.0026974709649146e-06 5.998830080448414 -0.1552347630628096 VVHIMDFQR ddPTM_PC-9_Lapatinib_30min_R1 2 VVHIMDFQR 9 0 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991;B3KM87;P43243-2;H0Y8T4;D6RAM9;D6RAY2;D6RBI2;D6RE02;D6RIA2 A0A0R4J2E8 MATR3 Matrin-3 0 ; 113.66 0.0017512 5249200.0 36336.0 31527.0 34403.0 29183.0 31548.0 34285.0 28023.0 26478.0 36443.0 23187.0 False True 35817.84197679371 31454.0011685131 31574.51813942039 31329.215171634147 29692.40866575442 32818.710472238534 29473.893822407943 27708.264542691326 32338.4055781971 27194.842055264562 1.3170821843350198 1.156616431328897 1.1610480426860204 1.152027840719495 1.0918397174513599 1.2067990836477487 1.0838045597952715 1.0188794068516156 1.1891374663062921 1.0 14.73104542635844 -1.5228787452803376 0.2361535237808511 1.0540511278706455 2.2692823779039286 0.5138196645467297 0.06189361692640981 43.9686216489109 0.5830212102220588 0.08494027072318948 20.830336732619426 0.029999999999999995 1.5228787452803376 1.2152312500332831 VVIKLS(ph)PQACSFTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVIKLSPQACSFTK 14 1 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 VVIKLS(0.977)PQACS(0.015)FT(0.008)K 65.949 0.017813 5129800.0 36884.0 35881.0 40093.0 45838.0 52358.0 45688.0 52440.0 45437.0 48055.0 43482.0 True False 43127.732707793526 39443.028550732066 41048.96917354922 43269.845468801104 42098.82575504786 43292.04085087268 47472.503567277796 44244.32689448094 48757.713463871834 51364.942396677376 0.8396336235467736 0.7678978445283626 0.799163150160654 0.8424003503136428 0.8196023161075537 0.8428324618090703 0.9242199319656714 0.861372072663766 0.9492410813455094 1.0 15.648496406544695 -7.883142699035672 0.43837225809467095 1.0044938318343337 0.7917030451090814 0.8251741067073692 0.02845388091533765 0.38097965832238717 0.19290469514219247 0.03145711050283023 0.023204502025781903 1.3087518270233034e-08 7.883142699035672 -0.2127907867252523 VVIKLS(ph)PQACSFTK ddPTM_PC-9_Lapatinib_30min_R1 1 VVIKLSPQACSFTK 14 1 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 VVIKLS(0.998)PQACS(0.001)FTK 68.171 0.015394999999999999 7952100.0 55539.0 63495.0 57146.0 58010.0 54108.0 67191.0 47998.0 48061.0 59796.0 40321.0 True False 54747.003675394764 63347.98122862115 52447.676469939215 62276.248915687116 50925.47382042092 64317.39755987111 50483.10158398229 50294.089515306536 53061.14480020506 47290.43112564465 1.157676138116376 1.339551780788668 1.1090547330937293 1.3168890076351187 1.0768663471288393 1.360050987672072 1.0675119761512666 1.063515140762442 1.1220270895655056 1.0 15.52926067380857 -7.3104327563648805 23.740345889821523 1.0685562501211479 1.2237558614521644 0.4226095690943402 0.09345792931484447 213.8068476708926 103601.61107266742 0.035742002801556094 0.02409729764296752 4.892910182490581e-08 7.3104327563648805 0.15519961133101656 VVKPKS(ph)PEPEATLTFPFLDK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVKPKSPEPEATLTFPFLDK 20 2 E7EPK0;E9PDJ9;H0Y8P3;Q9UPQ0-9;Q9UPQ0-8;Q9UPQ0-6;Q9UPQ0-10;G5EA03;Q9UPQ0-2;Q9UPQ0;Q9UPQ0-3;Q9UPQ0-5;Q9UPQ0-4 E7EPK0;Q9UPQ0-5 LIMCH1 LIM and calponin homology domains-containing protein 1 1 VVKPKS(0.998)PEPEAT(0.001)LTFPFLDK 58.92 0.0052209 2546500.0 34291.0 11714.0 19782.0 49762.0 47500.0 51541.0 50541.0 65510.0 43931.0 35451.0 True False 40095.789021877994 12876.888504870984 20253.67790365278 46973.99647058071 38192.71598160309 48838.099227255065 45753.39059484717 63790.43191358252 44573.40776571329 41877.98567003838 0.9574431143321331 0.3074858615772381 0.4836354370822396 1.121687104071681 0.9119998340542936 1.1661998170603582 1.0925403851881408 1.52324499120361 1.0643636997469854 1.0 15.353904429895152 -5.7668073939054745 24.846019860152847 1.1389206104124152 0.5553178602910344 0.5746421682057636 0.21342728064624022 78.46264471010153 363169.04105504084 0.06002755631416331 0.09205681921655494 1.7107738612612702e-06 5.7668073939054745 -0.5836027501213809 VVLASAS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 VVLASASPR 9 0 O95671-2;O95671 O95671-2 ASMTL N-acetylserotonin O-methyltransferase-like protein 1 VVLAS(0.027)AS(0.973)PR 78.939 0.020871999999999998 18395000.0 41648.0 37482.0 50636.0 63198.0 43362.0 45235.0 38578.0 53070.0 43719.0 37887.0 True False 54891.197667784705 49597.32349954073 49964.53355502534 48628.67749936673 37341.934782603006 42406.44829911653 42011.36726451131 44869.25092727944 46029.89708589253 36560.58766190527 1.5013762408687763 1.3565789466567912 1.366622823929235 1.330084678864064 1.0213712954486196 1.159895149697017 1.149088949362965 1.2272573773214122 1.2590032061725833 1.0 15.158001639499663 -6.073347489275531 5.236009788383984 1.1496061750163615 1.3957621600719046 0.6876635374438198 0.08412403927497997 0.13652473877290067 6.8471451482972325 0.02536285714164176 0.033547259973063515 8.446027880865628e-07 6.073347489275531 0.24615598505554304 VVLASAS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VVLASASPR 9 0 O95671-2;O95671 O95671-2 ASMTL N-acetylserotonin O-methyltransferase-like protein 1 VVLAS(0.017)AS(0.983)PR;VVLASAS(1)PR;VVLAS(0.078)AS(0.922)PR;VVLASAS(1)PR 112.11 0.0021902 32642000.0 107093.0 129664.0 136992.0 128156.0 136603.0 139329.0 139736.0 126565.0 126464.0 111679.0 True False 125221.72971683474 142536.185000477 140258.4088250534 120975.83480735819 109836.6227628404 132022.34196531333 126499.194478969 123242.80285670211 128313.29675361747 131925.51864952242 0.9491850477351756 1.0804292183921083 1.063163596102043 0.9170010172842032 0.8325654042311246 1.0007339240867277 0.9588682748712994 0.9341847136042944 0.9726192329362654 1.0 17.009364129763355 -5.762787109326141 24.99682006022425 0.9405945794780156 1.0358762885970336 0.32940668210825574 0.05569402020195188 37.91963902805035 703336.0472874544 0.015730732056366277 0.024856300880336166 1.726684103201694e-06 5.762787109326141 0.09528170911901801 VVLASAS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 3 VVLASASPR 9 0 O95671-2;O95671 O95671-2 ASMTL N-acetylserotonin O-methyltransferase-like protein 1 VVLAS(0.004)AS(0.996)PR;VVLASAS(1)PR;VVLAS(0.095)AS(0.905)PR 96.665 0.0050318 42411200.0 117493.0 105968.0 126335.0 104731.0 111744.0 100563.0 95003.0 98638.0 110118.0 79444.0 True False 115817.52827442264 105722.63760665448 115948.22396720269 112433.26711237415 105171.4376171567 96262.15491380262 99921.79048675098 103221.0815757226 97715.35124605281 93175.78954752411 1.2430002346838196 1.134657813151461 1.244402913356195 1.2066789845126862 1.128742113459787 1.0331241128330264 1.0724007917935172 1.1078101090098615 1.0487203995863466 1.0 16.507667518579737 -6.481435992906443 3.1682301385101246 1.060716259340374 1.2042361207821548 0.7759908780623633 0.038975567296275514 0.12453475212402074 2.516158155773543 0.012856140906151056 0.014054762622758118 3.300380459210695e-07 6.481435992906443 0.14351986144178075 VVLAYEPVWAIGTGK ddPTM_PC-9_AZD4547_30min_R2 1 VVLAYEPVWAIGTGK 15 0 P60174;P60174-3;P60174-4;U3KPZ0;U3KQF3 P60174 TPI1 Triosephosphate isomerase 0 120.55 0.00036733 7269800.0 6868.4 8716.3 12103.0 16204.0 10798.0 12254.0 9507.8 11392.0 10843.0 9104.8 False True 9052.40832840502 11533.673518463442 11942.50631204028 12468.41814930438 9298.884087047352 11487.7554428512 10353.975780950812 9631.628162117346 11416.13884357677 8786.043723285438 1.0303167857466542 1.3127266243731552 1.359258693465108 1.4191163329018763 1.0583698852309085 1.3075003727110395 1.1784571198422245 1.096241774507777 1.2993491955111554 1.0 13.100997963606774 -7.457333738401561 6.219048751775199 1.1461080071030134 1.2546337347373435 0.12964747487581618 0.13429426598613622 0.504509489063092 37.62587220037273 0.057410449853218117 0.037943507552637215 3.488721178016686e-08 7.457333738401561 0.1085257276343301 VVLAYEPVWAIGTGK ddPTM_PC-9_Lapatinib_30min_R1 2 VVLAYEPVWAIGTGK 15 0 P60174;P60174-3;P60174-4;U3KPZ0;U3KQF3 P60174 TPI1 Triosephosphate isomerase 0 ; 179.67 0.00012888 163126000.0 764200.0 643200.0 828440.0 713760.0 763890.0 721240.0 723560.0 772010.0 726770.0 726860.0 False True 753302.3678628836 641710.7099180886 760328.86107088 766252.2914335614 718959.4920655228 690394.2464925573 761022.3963937288 807880.4029610653 644913.5093726177 852496.7825199299 0.8836424762052081 0.7527426766599985 0.8918847280847124 0.8988330597196684 0.8433574258665484 0.8098496799621846 0.8926982623256263 0.9476638733732445 0.7564996403461977 1.0 19.70133486358676 -11.769422901913131 2.363588080494074 1.555008904406081 0.8549572115073842 0.34752019433174397 0.06036674585751791 11638434.672383044 1116234.5650305287 34850784.97777169 0.015914866684079286 1.7005018082710614e-12 11.769422901913131 -0.7000516928986968 VVLDDKDYFLFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVLDDKDYFLFR 12 1 P61604;B8ZZ54 P61604 HSPE1 10 kDa heat shock protein, mitochondrial 0 96.171 0.0056607 7578900.0 30966.0 30340.0 27253.0 35781.0 35359.0 33908.0 30777.0 31689.0 28527.0 28969.0 False True 36207.93219362147 33351.95468992536 27902.814877578043 33776.30657356717 28430.657776705306 32129.804788377503 27861.57975381595 30857.197327270896 28944.153407218222 34220.85038152219 1.0580664065897152 0.974609173006817 0.8153746784926297 0.9870095627958136 0.8307992776256856 0.938895568934378 0.8141697077422723 0.9017074965481418 0.845804621583771 1.0 15.062587990515333 -4.998910927913442 4.320944288956989 0.8882133533821798 1.0469201138014084 0.40355125649659407 0.06420883032250213 0.16552592457815932 7.688896652659097 0.014922473692770272 0.0581606413766719 1.0025108280139773e-05 4.998910927913442 0.1587067604192286 VVLGDGVQLPPGDYS(ph)TTPGGT(ph)LFSTTPGGTR ddPTM_PC-9_AZD4547_30min_R2 1 VVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 31 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 VVLGDGVQLPPGDY(0.168)S(0.294)T(0.25)T(0.291)PGGT(0.269)LFS(0.232)T(0.232)T(0.232)PGGT(0.03)R 60.728 0.0041087 9000600.0 16430.0 13577.0 22423.0 24072.0 25065.0 21277.0 17698.0 26257.0 21700.0 20274.0 True False 21654.398234770044 17965.49973729428 22125.65636907208 18522.572308692626 21585.157403393416 19946.5458264685 19273.087714431047 22199.583975835227 22847.017698571974 19564.21343092533 1.1068371499434135 0.9182837736218954 1.1309249128358951 0.9467578328200932 1.1032979925108342 1.0195424363413872 0.9851194775848183 1.1347036288586048 1.1677963839045777 1.0 14.255929488146723 -7.770916989400396 24.99316318151662 1.1134375221196338 1.0288883707295258 0.1445488392658545 0.07699437680349784 316.2226011530839 833888.5329600355 0.0380953575118254 0.018680952656751133 1.6946616853805273e-08 7.770916989400396 -0.08454915139010799 VVLGDGVQLPPGDYST(ph)TPGGT(ph)LFSTTPGGTR ddPTM_PC-9_AZD4547_30min_R2 1 VVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 31 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 VVLGDGVQLPPGDY(0.225)S(0.242)T(0.269)T(0.269)PGGT(0.6)LFS(0.12)T(0.12)T(0.12)PGGT(0.037)R 42.973 0.041254 13118000.0 5828.0 5340.9 6783.5 8221.1 8021.8 6838.5 6773.8 7760.8 7880.0 7666.3 True False 7681.182770069372 7067.24147800803 6693.546357739838 6325.852409728851 6908.11153634715 6410.887513949556 7376.655077410616 6561.5466854424385 8296.520712661162 7397.905170440111 1.0382915964861454 0.9553030642034562 0.9047894239690059 0.8550869825967934 0.9337929288347687 0.8665814668138229 0.9971275526598524 0.8869465793722906 1.121468918770635 1.0 12.852901092151216 -8.256143076510337 24.982154202943562 1.0607344623978519 0.9275480056514956 0.4294421048810587 0.06035404139633225 365.157683756356 1722434.5949853526 0.04289980632070924 0.015180914821922423 5.544430239188214e-09 8.256143076510337 -0.1331864567463562 VVLGDGVQLPPGDYST(ph)TPGGT(ph)LFSTTPGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 31 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 VVLGDGVQLPPGDY(0.226)S(0.24)T(0.267)T(0.267)PGGT(0.283)LFS(0.254)T(0.228)T(0.228)PGGT(0.008)R;VVLGDGVQLPPGDY(0.078)S(0.084)T(0.387)T(0.387)PGGT(0.308)LFS(0.256)T(0.229)T(0.234)PGGT(0.037)R 59.873000000000005 0.0010294 13628400.0 8967.5 11102.8 14327.1 11798.7 16641.2 13183.9 14730.8 13175.900000000001 14050.0 11001.8 True False 10485.520633801605 12205.012608151064 14668.712399829317 11137.65709090151 13380.476319853738 12492.513075070485 13335.391982243633 12830.046586020022 14255.45467001142 12996.339249799124 0.8068057036879576 0.939111573925689 1.128680324350262 0.8569841766075518 1.0295573286193302 0.9612332238298237 1.0260883257914146 0.9872046535118209 1.0968823140125215 1.0 13.665817688195196 -4.862829246433206 3.7942744713304872 1.0058581671738207 0.8020524387806163 0.43719911975425607 0.07031367009622863 0.20965970628231395 5.050466349331062 0.016766643675238693 0.10084872611421769 1.3714208680525142e-05 4.862829246433206 -0.20380572839320443 VVLGDGVQLPPGDYST(ph)TPGGT(ph)LFSTTPGGTR ddPTM_PC-9_Lapatinib_30min_R1 2 VVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 31 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 VVLGDGVQLPPGDY(0.025)S(0.092)T(0.45)T(0.45)PGGT(0.609)LFS(0.083)T(0.083)T(0.086)PGGT(0.123)R;VVLGDGVQLPPGDY(0.088)S(0.088)T(0.448)T(0.376)PGGT(0.24)LFS(0.234)T(0.234)T(0.234)PGGT(0.059)R 70.21300000000001 5.8956e-05 10059000.0 20091.6 19376.4 22853.7 20436.8 24344.0 26103.0 19525.0 21011.0 28737.0 22715.0 True False 19805.090099651803 19331.535136282462 20974.75700383316 21939.790447166255 22912.133782145473 24986.635539064988 20535.90896344129 21987.247764426575 25500.336445974517 26641.25748416503 0.7433992224812777 0.7256239743102477 0.7873035653928907 0.8235268346551126 0.8600244862977633 0.9378924982770234 0.7708310681523713 0.8253081813985433 0.9571746551802724 1.0 14.701374559682097 -1.5228787452803751 0.08330728956507874 1.1259236044330678 0.0505511423507326 0.6637418990033008 0.05176175608601269 121.39391771873126 0.7368338366971754 1.369656359336043 14.978442767299928 0.029999999999997404 1.5228787452803751 -1.0753724620823353 VVLGDGVQLPPGDYST(ph)TPGGTLFS(ph)TTPGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 31 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 VVLGDGVQLPPGDY(0.103)S(0.183)T(0.386)T(0.334)PGGT(0.215)LFS(0.377)T(0.285)T(0.087)PGGT(0.03)R;VVLGDGVQLPPGDY(0.067)S(0.361)T(0.422)T(0.151)PGGT(0.013)LFS(0.472)T(0.307)T(0.202)PGGT(0.006)R 78.472 5.3292e-06 8209900.0 15569.5 16535.1 19160.9 18114.8 23090.9 19368.7 21318.9 20378.6 17222.3 17056.8 True False 18205.10883835787 18176.59545133107 19617.76852411791 17099.886484974002 18566.403904412593 18352.97127535234 19299.419456530104 19843.683342911496 17474.14355610946 20149.06281844549 0.9035213698223213 0.9021062475765016 0.9736318111112737 0.8486690740434778 0.9214524800337587 0.9108597973376253 0.9578321150928379 0.9848439861304896 0.8672434898616092 1.0 14.298425116633979 -7.254610624086764 22.52826034562421 0.9512168974095844 0.9102991723714688 0.18790378630088667 0.043189040537725924 246.95887588281957 814727.4977401034 0.016171890884996775 0.012195149381411825 5.564028884984269e-08 7.254610624086764 -0.04091772503811553 VVLGDGVQLPPGDYST(ph)TPGGTLFSTT(ph)PGGTR ddPTM_PC-9_Lapatinib_30min_R1 1 VVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 31 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 VVLGDGVQLPPGDY(0.076)S(0.142)T(0.595)T(0.186)PGGT(0.013)LFS(0.239)T(0.167)T(0.427)PGGT(0.155)R 83.876 1.0745e-05 0.0 12938.0 17045.0 17349.0 16026.0 16914.0 19855.0 18628.0 15438.0 20508.0 16486.0 True False 12753.501747461378 17005.533349741683 15922.63218907667 17204.605501168804 15919.151774203436 19005.847934265603 19592.466692495993 16155.305839189838 18198.173081186127 19335.583133785818 0.6595871280021903 0.8794942067212471 0.8234885950377382 0.8897898440469854 0.8233085945252554 0.9829467155327705 1.0132855345987115 0.835522038689438 0.9411752909271068 1.0 14.23897065426419 -3.483752788699849 0.4786060426306405 0.9421469409072988 3.846716618265369e-18 0.5875514215090767 0.06528364144370051 11.883425599577826 0.798041135455792 0.039975558911688 8.257008452240203 0.00032828210633857813 3.483752788699849 -0.9421469409072988 VVLGDGVQLPPGDYSTT(ph)PGGT(ph)LFSTTPGGTR ddPTM_PC-9_AZD4547_30min_R2 1 VVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 31 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 VVLGDGVQLPPGDY(0.037)S(0.04)T(0.187)T(0.721)PGGT(0.275)LFS(0.242)T(0.242)T(0.242)PGGT(0.015)R 62.848 0.0030783 0.0 2560.4 3480.5 4841.7 4882.6 5543.6 5580.9 3218.6 5119.1 3538.1 4483.3 True False 3374.553940371591 4605.503560112894 4777.495894489418 3756.992005418022 4773.966829501365 5231.925440754711 3505.0491647456097 4328.060720215491 3725.116742825691 4326.341031610316 0.7800018342787789 1.0645262420282826 1.1042809292154152 0.8683994114120088 1.1034652133570795 1.2093187759651314 0.8101647880127906 1.0003974926138761 0.8610316929729318 1.0 12.078931677474902 -7.293649691924693 24.995413141601063 0.9179316583845333 1.024120522282597 0.13823008773724987 0.1268394496095362 1398.0560792404412 1084895.4801290024 0.052856990440734324 0.03563994250628953 5.0856949651391064e-08 7.293649691924693 0.10618886389806381 VVLGDGVQLPPGDYSTTPGGT(ph)LFST(ph)TPGGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 31 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 VVLGDGVQLPPGDY(0.077)S(0.066)T(0.058)T(0.362)PGGT(0.41)LFS(0.289)T(0.324)T(0.342)PGGT(0.072)R 59.873000000000005 0.0010294 1205600.0 3935.7 5553.3 7222.1 8475.8 9878.9 7276.6 9355.9 6343.5 7088.8 5650.8 True False 4601.936276381711 6104.594923518871 7394.302253966771 8000.928404914359 7943.200461277023 6895.002286277802 8469.641421149778 6176.989846493825 7192.460289307973 6675.2453082918155 0.6894033198548233 0.9145124473457031 1.107719928252189 1.1985969107346235 1.1899488474843294 1.0329211838421894 1.268813508715404 0.9253577301228061 1.0774825429072525 1.0 12.70460513997212 -4.932794750560555 2.274000389517135 1.1080792393071128 0.6513441006516009 0.6407116376934718 0.09654728809006329 0.2673265449141154 2.1125269687285675 0.025851246943516395 0.218384939492818 1.167361186629621e-05 4.932794750560555 -0.45673513865551196 VVLGIFQTMNLTS(ph)LCEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVLGIFQTMNLTSLCEK 17 0 A0A0C4DGQ4;Q86W25 A0A0C4DGQ4 NLRP13 NACHT, LRR and PYD domains-containing protein 13 1 VVLGIFQT(0.003)MNLT(0.158)S(0.839)LCEK 55.66 0.029179000000000004 4490100.0 8983.0 9643.6 40878.0 9774.6 20466.0 15504.0 9153.3 10320.0 13822.0 7744.4 True False 10503.644477662658 10600.952875667894 41852.686550678314 9226.960851680775 16455.834216410283 14690.942946767858 8286.233159846755 10049.11093494384 14024.120601345054 9148.398415363334 1.1481402537107912 1.158776913111394 4.574864872565359 1.0085875617513014 1.7987666768835986 1.6058486174035305 0.9057577931817329 1.0984557600888805 1.5329591000096467 1.0 13.159303481560835 -6.630676197502765 1.4703291252280792 1.1655379417942129 2.095233326939987 0.13186792844315087 0.9652885945199905 0.8351634562779212 3.7436931563754925 0.42387428116534037 0.42867871920531336 2.3405816857180562e-07 6.630676197502765 0.9296953851457741 VVLIGGKPDR ddPTM_PC-9_AZD4547_30min_R2 2 VVLIGGKPDR 10 1 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 ; 112.11 0.001943 22067000.0 72616.0 71050.0 97741.0 127303.0 110566.0 100630.0 92935.0 114574.0 79649.0 90905.0 False True 95706.37749336967 94015.52304152299 96444.8904771652 97955.26016174376 95215.81940808262 94337.59019210996 101206.03496104924 96869.22094859842 83859.08353334379 87722.44361932858 1.0910135826663399 1.0717385330657594 1.0994323288084367 1.116649925836773 1.0854214210136637 1.0754099669348907 1.1537074297682892 1.1042695227342534 0.9559592741995442 1.0 16.42065838021103 -8.256385760471673 24.988605431543764 0.9779796308600761 1.0998429276968924 0.8021828643373644 0.024178877613166765 160.88297642937522 795527.9208819863 0.01797732148646576 0.006318950533607813 5.541332874440397e-09 8.256385760471673 0.12186329683681629 VVLIGGKPDR ddPTM_PC-9_Lapatinib_30min_R1 1 VVLIGGKPDR 10 1 P61978;P61978-2;P61978-3;Q5T6W2 P61978 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 114.86 0.0015199999999999999 19346000.0 96907.0 96709.0 106830.0 100500.0 115340.0 98227.0 88340.0 92304.0 100520.0 99508.0 False True 95525.08840943278 96485.07625228343 98046.84977572518 107891.10525817194 108555.92796716471 94026.06018832063 92913.81294906026 96592.78081231876 89198.37907747366 116707.82521392436 0.8184977162785458 0.8267232816259508 0.8401051908559363 0.9244547660828102 0.9301512368016687 0.8056534342574865 0.7961232486232187 0.8276461379968746 0.7642879036943226 1.0 16.832541770862015 VVNANQNAS(ph)PNVPGK ddPTM_PC-9_AZD4547_30min_R2 2 VVNANQNASPNVPGK 15 0 Q8IWI9-3;Q8IWI9;H3BP52;H3BTF4 Q8IWI9-3 MGA MAX gene-associated protein 1 VVNANQNAS(1)PNVPGK;VVNANQNAS(1)PNVPGK 172.26 0.00010369 6680600.0 30547.0 31475.0 40204.0 40937.0 45694.0 39837.0 33567.0 44138.0 34106.0 35099.0 True False 40260.310582928796 41648.678222828144 39670.86869117306 31499.60712034521 39350.17683585312 37345.98609244843 36554.39797210458 37317.48629033843 35908.77353122099 33870.19469330414 1.1886648703229312 1.2296557076201793 1.171261902991531 0.9300096266223241 1.1617936416418748 1.1026209453656146 1.0792497150697244 1.1017795034321367 1.0601879870008502 1.0 15.047728659332718 -5.540758769133102 24.9947807189148 1.071293810129485 1.2069849666033738 0.5138726103425031 0.06015084241394766 178.86215594157434 250033.36775310454 0.015784188406622445 0.027346075243796494 2.878997122879457e-06 5.540758769133102 0.13569115647388874 VVNANQNAS(ph)PNVPGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVNANQNASPNVPGK 15 0 Q8IWI9-3;Q8IWI9;H3BP52;H3BTF4 Q8IWI9-3 MGA MAX gene-associated protein 1 VVNANQNAS(1)PNVPGK 138.81 2.4072e-06 0.0 10941.0 14119.0 11993.0 13250.0 14937.0 11665.0 14832.0 12660.0 11214.0 7312.3 True False 12793.095205399883 15520.6410107797 12278.958603705776 12507.645457079589 12010.202076151687 11053.266864941124 13427.005585619074 12327.688414378785 11377.983535196312 8637.96210586505 1.4810316424881695 1.796794292515061 1.421511052400721 1.4479856827094761 1.3903976341823652 1.2796151140135377 1.554418208954903 1.427152407395775 1.317206928642443 1.0 13.076475272218774 -12.84917857267729 0.10660645839030591 3.994686070597314e-14 1.7759649165755849 0.6191096184634699 0.11894619334540746 77.83065061657177 0.8143016867047201 19.824495450270447 1.9344404527259533 1.415211755257493e-13 12.84917857267729 1.775964916575545 VVNANQNAS(ph)PNVPGK ddPTM_PC-9_Lapatinib_30min_R1 2 VVNANQNASPNVPGK 15 0 Q8IWI9-3;Q8IWI9;H3BP52;H3BTF4 Q8IWI9-3 MGA MAX gene-associated protein 1 VVNANQNAS(1)PNVPGK;VVNANQNAS(1)PNVPGK 178.85 1.4481e-28 3492600.0 33654.0 41023.0 44508.0 37470.0 43536.0 41297.0 37606.0 40914.0 41410.0 35236.0 True False 33174.08778861226 40928.01376394559 40848.72404584843 40225.66879625574 40975.29807506924 39530.82357800891 39553.0546724288 42815.01380390032 36745.969733368314 41326.49565098125 0.8027316922484954 0.9903577140824862 0.9884390970585121 0.9733626856721066 0.9915018786282289 0.9565491328338723 0.9570870708823254 1.0360184944179687 0.8891624889684017 1.0 15.334779412719962 -4.758678652905131 24.997525339061042 0.9765748214871014 0.8027314595103443 0.6735472305613894 0.03614951480683825 41.216520588055374 373131.9979921146 0.008245301860455634 0.055552113891189525 1.743096163795329e-05 4.758678652905131 -0.1738433619767571 VVNANQNAS(ph)PNVPGKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVNANQNASPNVPGKR 16 1 Q8IWI9-3;Q8IWI9;H3BP52;H3BTF4 Q8IWI9-3 MGA MAX gene-associated protein 1 VVNANQNAS(1)PNVPGKR 51.523999999999994 0.039998 11807000.0 17846.0 16243.0 18458.0 16646.0 23058.0 17685.0 16361.0 14676.0 14223.0 14803.0 True False 20866.97532543334 17855.49769375271 18898.10872235481 15713.378587060148 18539.950423237966 16757.567467336805 14811.167636617703 14290.770550507355 14430.984467727581 17486.666719516477 1.193307773295878 1.021092125798028 1.080715325881007 0.8985919866318947 1.0602335322457963 0.9583054184153953 0.8469977654510502 0.8172381151725014 0.8252564481955548 1.0 14.093967690791436 -5.122879480393349 0.4589970655335653 0.8651639845909473 1.2904525758858685 0.5650631545959317 0.07759366056611579 2.741933050853909 0.5651069256178938 0.05853659136025698 0.6136900016983952 7.535646539228496e-06 5.122879480393349 0.42528859129492114 VVNGAAASQPPS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 VVNGAAASQPPSK 13 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 VVNGAAAS(0.005)QPPS(0.995)K 63.708999999999996 0.044376 4175300.0 14615.0 27115.0 12546.0 18132.0 18806.0 18040.0 16446.0 18293.0 11693.0 14647.0 True False 14406.587419937247 27052.216883440648 11514.516308960503 19465.487766578863 17699.868054018552 17268.471253293963 17297.493409103972 19142.959561879765 10376.011207251282 17178.7144340993 0.8386301242274885 1.5747521147299999 0.6702781138328074 1.1331166741988783 1.0303371723139407 1.0052248856885646 1.006914311048148 1.1143417998660883 0.6040039402864262 1.0 14.0683344562502 -8.239959027478081 24.513918877175225 0.8020018711717738 1.0513803035015992 0.14629807689470165 0.23622476745545465 960.482483695845 1096131.0760141774 0.14836576137777185 0.05595307766077543 5.754942284659483e-09 8.239959027478081 0.24937843232982537 VVNGAAASQPPS(ph)KR ddPTM_PC-9_AZD4547_30min_R2 2 VVNGAAASQPPSKR 14 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 VVNGAAASQPPS(1)KR;VVNGAAAS(0.002)QPPS(0.998)KR 102.5 0.00066233 60105000.0 41835.0 37339.0 49440.0 43032.0 50067.0 58569.0 43284.0 44467.0 39754.0 44224.0 True False 55137.65977794303 49408.10154605813 48784.39329647784 33111.63723777256 43116.061269327634 54906.67117123807 47136.19214778132 37595.64690000631 41855.315280600495 42675.73122073798 1.2920144119557408 1.1577564140728445 1.1431413569492959 0.7758891597311912 1.0103180434404762 1.2866017664052714 1.1045198476851361 0.8809608136658467 0.9807755856392026 1.0 15.381128252650024 -5.266365213634087 2.428938117697061 1.0162953227027947 1.2530165684912165 0.3103254244517467 0.13095232378005547 0.42318756186381423 4.73195497892996 0.03911907016309241 0.1315860007285687 5.415452942186706e-06 5.266365213634087 0.2367212457884218 VVNGAAASQPPS(ph)KR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VVNGAAASQPPSKR 14 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 VVNGAAAS(0.093)QPPS(0.907)KR;VVNGAAAS(0.022)QPPS(0.978)KR;VVNGAAAS(0.049)QPPS(0.951)KR;VVNGAAAS(0.004)QPPS(0.996)KR 82.449 0.0042312 57632900.0 51809.2 41695.2 43999.0 54866.0 61793.0 49469.0 58042.0 47665.600000000006 47704.5 38311.9 True False 60579.47428165643 45834.42390202291 45048.10302713673 51792.035897972026 49685.10523476205 46874.758554802596 52543.841572310055 46414.42850587783 48402.08806445266 45257.544193166446 1.338549745940556 1.0127465977030095 0.9953722374962328 1.1443845843008034 1.0978303423336022 1.035733586310685 1.1609963047938379 1.0255622423473447 1.069481098175915 1.0 15.465870681421938 -4.754689409456674 24.999309168482192 1.0651937545563526 1.3385502110151386 0.6925701379166929 0.055540433799898176 134.53538433184082 498223.2926142921 0.01379044581383745 0.13117247837181903 1.7591812622980243e-05 4.754689409456674 0.27335645645878603 VVNGAAASQPPS(ph)KR ddPTM_PC-9_Lapatinib_30min_R1 2 VVNGAAASQPPSKR 14 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 VVNGAAAS(0.051)QPPS(0.949)KR;VVNGAAAS(0.004)QPPS(0.996)KR 74.812 0.0083512 62267000.0 46720.0 37223.0 42763.0 43788.0 48745.0 47940.0 38382.0 36208.0 42587.0 25933.7 True False 46053.76423260131 37136.81243047432 39247.19120995363 47008.315592485946 45877.91493635725 45889.71795359822 40369.23215543166 37890.355863802666 37790.403599008816 30416.305490516865 1.5141143373563188 1.2209507970010611 1.2903339369138713 1.5454972204675583 1.5083329219803165 1.5087209709905638 1.3272233923353347 1.2457251218632075 1.2424389809864 1.0 14.892557306635416 -8.383895117966272 0.992457466223712 1.0121333058117912 1.4203311445168214 0.608972699606126 0.10466532239166178 0.39382482691382065 0.8414215622060756 0.10877019414804016 0.03702816192970612 4.13147264928213e-09 8.383895117966272 0.40819783870503024 VVNGGVPWPSPCPS(ph)PSSRPPSR ddPTM_PC-9_AZD4547_30min_R2 1 VVNGGVPWPSPCPSPSSRPPSR 22 1 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;F8WB06 Q99700;F8WB06 ATXN2 Ataxin-2 1 VVNGGVPWPS(0.08)PCPS(0.772)PS(0.063)S(0.035)RPPS(0.051)R 43.516000000000005 0.037883 6027400.0 16278.0 18465.0 17777.0 25231.0 20815.0 24984.0 20313.0 21625.0 17105.0 22544.0 True False 21454.065396566446 24433.45014724452 17541.26536471455 19414.382765064114 17925.19654305342 23421.746530454882 22120.8176485048 18283.35314306422 18009.13537945039 21754.741421859544 0.9861788278949171 1.1231321794840257 0.8063191846118097 0.8924207550247507 0.8239673455756118 1.076627208582691 1.0168274225625782 0.840430726733106 0.8278257613006834 1.0 14.409042248571401 -5.252522629267829 24.945429155134455 0.9108403086767831 1.0546555013888008 0.27703142539316894 0.09311601471560665 849.6939122918579 2377083.3130243868 0.024831462340717914 0.06367429975354724 5.590843952636461e-06 5.252522629267829 0.1438151927120177 VVNGGVPWPSPCPS(ph)PSSRPPSR ddPTM_PC-9_Lapatinib_30min_R1 1 VVNGGVPWPSPCPSPSSRPPSR 22 1 Q99700;A0A2R8Y5A6;Q99700-4;Q99700-2;Q99700-5;H0YH87;A0A5F9ZHW5;A0A2R8Y7P6;A0A2R8YDM9;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;F8WB06 Q99700;F8WB06 ATXN2 Ataxin-2 1 VVNGGVPWPS(0.001)PCPS(0.961)PS(0.027)S(0.009)RPPS(0.002)R 64.035 0.0015739 4978000.0 50307.0 45530.0 50127.0 49658.0 43988.0 50275.0 38680.0 47337.0 53985.0 41927.0 True False 49589.61295482609 45424.578082354834 46005.75155581565 53310.01497423191 41400.712323735446 48124.85544674912 40682.661137306444 49536.4498322146 47904.640812747864 49174.02608578416 1.008451349261436 0.9237514537270468 0.9355701620924541 1.0841092181720593 0.8419223646953748 0.978664129774431 0.8273201194942933 1.0073702272374077 0.9741858583874778 1.0 15.585608859097011 VVNTDHGS(ph)PEQLQIPVTDSGR ddPTM_PC-9_AZD4547_30min_R2 5 VVNTDHGSPEQLQIPVTDSGR 21 0 Q6IQ49-3;Q6IQ49-2;Q6IQ49 Q6IQ49-3 SDE2 Protein SDE2 homolog 1 VVNT(0.006)DHGS(0.994)PEQLQIPVTDSGR;VVNTDHGS(1)PEQLQIPVTDSGR;VVNTDHGS(1)PEQLQIPVTDSGR;VVNTDHGS(1)PEQLQIPVTDSGR;VVNTDHGS(1)PEQLQIPVTDSGR 148.58 5.8201999999999996e-05 254593600.0 250503.0 182578.0 296207.0 392850.0 324701.0 293400.0 237114.0 364584.0 235902.0 281473.0 True False 330157.74321391416 241592.7679926137 292279.1016417846 302284.5019719965 279621.87089723715 275053.6516184547 258216.68664931692 308245.9201068642 248371.2981165219 271618.715943713 1.2155191223359296 0.8894555264839648 1.0760639252206503 1.1129001214873513 1.02946466676907 1.0126461671199918 0.9506586678026513 1.1348478658250538 0.9144115759975517 1.0 18.051223366644237 -6.509357614410532 14.99739802121464 1.0091819218975264 1.0618568483521003 0.11012344112034678 0.09188916977191675 10.194190925293936 11306.210753010448 0.028000000907368056 0.030243223064605494 3.0948698174830327e-07 6.509357614410532 0.052674926454573834 VVNTDHGS(ph)PEQLQIPVTDSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 VVNTDHGSPEQLQIPVTDSGR 21 0 Q6IQ49-3;Q6IQ49-2;Q6IQ49 Q6IQ49-3 SDE2 Protein SDE2 homolog 1 VVNT(0.004)DHGS(0.996)PEQLQIPVTDSGR;VVNTDHGS(1)PEQLQIPVTDSGR;VVNTDHGS(1)PEQLQIPVTDSGR;VVNT(0.005)DHGS(0.995)PEQLQIPVTDSGR;VVNTDHGS(1)PEQLQIPVTDSGR;VVNTDHGS(1)PEQLQIPVTDSGR;VVNT(0.003)DHGS(0.997)PEQLQIPVTDSGR 186.65 2.4121e-15 200340600.0 274351.7 267938.2 358103.0 350261.0 375561.0 317021.0 315963.4 316405.0 280596.4 257543.9 True False 320794.0241169277 294537.3337541244 366641.5336331897 330637.01173148263 301972.51803719596 300395.8606764254 286033.0593750804 308099.7040088089 284699.5915137654 304234.57035360957 1.054429888569439 0.9681257899514374 1.2051277841536712 1.0867831730864304 0.9925647755487339 0.9873824014387238 0.9401727720903851 1.012704452523942 0.9357897466512802 1.0 18.214824571102028 -6.327848668046371 4.486336927889323 0.9757629809600682 1.079810127058614 0.41855364012600615 0.058229052156517816 0.22932182280799615 9.155216044751011 0.018932874284190833 0.021889311493924618 4.700578739468504e-07 6.327848668046371 0.10404714609854582 VVNTDHGS(ph)PEQLQIPVTDSGR ddPTM_PC-9_Lapatinib_30min_R1 1 VVNTDHGSPEQLQIPVTDSGR 21 0 Q6IQ49-3;Q6IQ49-2;Q6IQ49 Q6IQ49-3 SDE2 Protein SDE2 homolog 1 VVNT(0.062)DHGS(0.937)PEQLQIPVT(0.001)DSGR 82.03399999999999 0.00068831 16061000.0 23391.0 17948.0 21011.0 17401.0 28395.0 24241.0 20104.0 23788.0 24029.0 16263.0 True False 23057.44005061594 17906.442508721833 19283.55668480544 18680.72758803433 26724.861926717906 23204.268938530968 21144.886750372512 24893.277322363498 21322.600983412387 19074.037880914635 1.20883895662633 0.9387861458867558 1.010984501823835 0.9793798095958565 1.4011119246784467 1.2165367964246845 1.10856898169055 1.3050869185528648 1.1178860562475683 1.0 14.219322667044905 -6.218214986763039 24.999067438181658 1.2038884289504606 1.0259813093644108 0.27771578998201685 0.12279556136485012 546.9496328970721 316331.08098835486 0.03478733286755034 0.044909974826862625 6.050412898534161e-07 6.218214986763039 -0.17790711958604977 VVPEDGS(ph)PEKR ddPTM_PC-9_AZD4547_30min_R2 3 VVPEDGSPEKR 11 1 Q02040 Q02040 AKAP17A A-kinase anchor protein 17A 1 VVPEDGS(1)PEKR;VVPEDGS(1)PEKR;VVPEDGS(1)PEKR 77.192 0.009065700000000001 136117000.0 207062.0 209466.0 218885.0 268683.0 240582.0 231457.0 219485.0 215855.0 218387.0 240718.0 True False 272903.4088428457 277171.78816911543 215982.44188308163 206742.28546096967 207181.34204760342 216983.95720058857 239018.73980121495 182499.56960444534 229930.490974103 232290.53608885655 1.1748365363385007 1.1932117116604817 0.929794409706228 0.8900159642400839 0.8919060825119097 0.9341058867658178 1.02896460538446 0.7856521952088268 0.9898401150796313 1.0 17.82557085193349 -5.2635850707990715 22.84914190407593 0.9243386370838473 1.1840241923052408 0.704438673217956 0.06536016649437616 25.733774319129285 274051.14225175284 0.016235263387481023 0.036762107322078276 5.45023124601418e-06 5.2635850707990715 0.25968555522139347 VVPEDGS(ph)PEKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVPEDGSPEKR 11 1 Q02040 Q02040 AKAP17A A-kinase anchor protein 17A 1 VVPEDGS(1)PEKR 57.803999999999995 0.034277999999999996 43087000.0 37732.0 30054.0 30585.0 35584.0 45486.0 37750.0 37639.0 34573.0 31052.0 30661.0 True False 44119.282359030105 33037.562500033484 31314.262394258436 33590.343844884526 36573.34482398311 35770.323544923034 34073.56143723814 33665.495383121466 31506.076755387552 36219.596587657565 1.2181052942501434 0.9121460649092814 0.8645668462505542 0.9274080058730141 1.0097667635659446 0.9875958573517732 0.940749335923009 0.9294828919931579 0.8698627186290577 1.0 15.144482857250368 -4.75835775006075 24.99693968811209 0.937009524683921 1.2181056787481275 0.7595564524870944 0.047284308165743534 44.18496328093802 358348.64519051055 0.01260083332962567 0.08685751792453567 1.7443846241606956e-05 4.75835775006075 0.2810961540642065 VVPEDGS(ph)PEKR ddPTM_PC-9_Lapatinib_30min_R1 3 VVPEDGSPEKR 11 1 Q02040 Q02040 AKAP17A A-kinase anchor protein 17A 1 VVPEDGS(1)PEKR;VVPEDGS(1)PEKR;VVPEDGS(1)PEKR 104.41 0.0012314 160787000.0 665470.0 608890.0 593230.0 541285.0 528580.0 532230.0 529300.0 529010.0 499600.0 485973.0 True False 655980.2757677467 607480.1526150901 544456.9193340223 581092.9045738267 497489.9636282642 509467.7635887269 556704.5641152101 553589.7358459535 443329.7869787687 569972.7855316804 1.1508975383023543 1.0658055402564917 0.9552331850829395 1.019509912270238 0.8728310829159974 0.8938457703967158 0.9767213071338248 0.9712564352165611 0.7778086923312014 1.0 19.1205335110549 -4.552821174014514 0.7627787329093277 0.9180007648587241 1.3743968812901208 0.5642465743762768 0.06523856810630257 2.6840219334091255 0.9387230114136069 0.025072816236800834 1.1337154096026563 2.8001340712294185e-05 4.552821174014514 0.45639611643139677 VVPGQFDDADS(ph)SDSENRDLK ddPTM_PC-9_Lapatinib_30min_R1 1 VVPGQFDDADSSDSENRDLK 20 1 E9PFQ8;Q9BRS2 E9PFQ8 RIOK1 Serine/threonine-protein kinase RIO1 1 VVPGQFDDADS(0.821)S(0.174)DS(0.005)ENRDLK 83.436 0.0028071999999999997 0.0 8655.0 5900.4 5254.0 4971.4 6568.5 7206.6 5662.0 5347.3 5762.1 6344.7 True False 8531.578112867392 5886.737986319496 4822.036401026504 5337.0133401042385 6182.153744167868 6898.390517405115 5955.15065562123 5595.755079278395 5113.1116203970405 7441.372941218665 1.14650591769295 0.7910822415191882 0.6480035927666871 0.717208152616821 0.8307813347082997 0.92703195658883 0.80027579623579 0.7519788516824403 0.6871193878853856 1.0 12.861353109322337 -4.761849660561518 7.93453728552491 0.7851962021627557 1.1510868543123915 0.5182271631528493 0.10135664398640476 0.07530466103246426 40.97473705443619 0.025575116014269803 0.1487535681271085 1.730415272276374e-05 4.761849660561518 0.3658906521496359 VVPGQFDDADSS(ph)DSENR ddPTM_PC-9_AZD4547_30min_R2 2 VVPGQFDDADSSDSENR 17 0 E9PFQ8;Q9BRS2 E9PFQ8 RIOK1 Serine/threonine-protein kinase RIO1 1 VVPGQFDDADS(0.18)S(0.778)DS(0.042)ENR;VVPGQFDDADS(0.216)S(0.783)DS(0.001)ENR 220.64 7.691e-23 15201900.0 22004.0 23372.8 23724.0 21834.0 21352.0 25931.0 23452.2 26583.0 25581.6 22643.5 True False 29000.81428836763 30927.600519984677 23409.40425901376 16800.508631937308 18387.643362348143 24309.530470750306 25539.40036706858 22475.208166569973 26933.79115012853 21850.757957145 1.3272223483160512 1.415401725681174 1.0713314524340836 0.7688753252810479 0.8415105507283124 1.1125257310720111 1.1688107303718234 1.0285779656087757 1.2326250285208722 1.0 14.415395704220332 -5.31651683973191 5.429778018479698 1.0190202776874346 1.3715342430263788 0.5171894656747376 0.13290694502472714 0.16030497746816894 10.465701370558065 0.03863673293710698 0.08448839761204216 4.824842714100652e-06 5.31651683973191 0.3525139653389442 VVPGQFDDADSS(ph)DSENR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VVPGQFDDADSSDSENR 17 0 E9PFQ8;Q9BRS2 E9PFQ8 RIOK1 Serine/threonine-protein kinase RIO1 1 VVPGQFDDADS(0.227)S(0.773)DSENR;VVPGQFDDADS(0.323)S(0.676)DSENR 216.77 2.1187e-22 6965700.0 14595.9 23074.8 22097.0 17549.4 19760.199999999997 16273.9 17095.6 13048.1 15254.5 11902.3 True False 17066.697587834395 25365.513647959437 22623.876283339156 16566.16401392246 15888.330659782594 15420.46803543638 15476.181006574267 12705.601200604731 15477.56820382131 14060.09277144504 1.2138396143797525 1.804078682857259 1.6090844243422415 1.1782400218273847 1.1300302862901845 1.096754359029135 1.1007168486117809 0.9036641085618455 1.100815510638383 1.0 13.77931849319618 -5.864900341949486 3.743981832767306 1.061337628926808 1.5697121349843093 0.6781835632158472 0.149457495372365 0.12404591783869753 3.302571182817839 0.04263940191616867 0.06696975748177102 1.3648963049691418e-06 5.864900341949486 0.5083745060575013 VVPGQFDDADSS(ph)DSENR ddPTM_PC-9_Lapatinib_30min_R1 2 VVPGQFDDADSSDSENR 17 0 E9PFQ8;Q9BRS2 E9PFQ8 RIOK1 Serine/threonine-protein kinase RIO1 1 VVPGQFDDADS(0.226)S(0.773)DS(0.001)ENR;VVPGQFDDADS(0.079)S(0.921)DSENR 261.06 2.553e-58 19084500.0 19444.0 33368.0 25294.2 28092.0 31351.0 26246.6 28538.7 27660.9 27050.5 22568.9 True False 19166.7249944071 33290.73844612379 23214.608514435597 30157.979392164838 29506.995818437517 25124.09410181291 30016.29424506844 28946.12639508007 24003.78783560685 26469.90429383105 0.7240949865796835 1.257682614813321 0.8770189818875123 1.139330881494472 1.1147375332714853 0.9491569679633565 1.1339781931914237 1.0935485853579803 0.9068331932428279 1.0 14.692065358097723 -4.736363888519433 24.996513877012546 1.0538947347993763 0.7240934532793836 0.4325330289305104 0.11282875310268835 2250.4558276330254 2243251.562833849 0.026006046329666955 1.8752029418014409 1.835000181231098e-05 4.736363888519433 -0.3298012815199928 VVPGQFDDADSS(ph)DSENRDLK ddPTM_PC-9_AZD4547_30min_R2 2 VVPGQFDDADSSDSENRDLK 20 1 E9PFQ8;Q9BRS2 E9PFQ8 RIOK1 Serine/threonine-protein kinase RIO1 1 VVPGQFDDADS(0.288)S(0.711)DS(0.001)ENRDLK;VVPGQFDDADS(0.318)S(0.682)DSENRDLK 94.838 0.00026458 43448000.0 215896.0 157938.0 242952.0 377030.0 315840.0 265013.0 218914.0 253322.0 216468.0 276841.0 True False 284546.437084231 208988.36985407557 239730.2977379833 290111.55855543254 271991.0677952431 248441.6952159563 238396.92190738794 214176.90566045424 227910.05655181935 267148.8808538423 1.065123073601446 0.7822917662470521 0.897365906874752 1.0859546093855925 1.0181254247666116 0.9299746808667309 0.8923747729933983 0.8017136548576105 0.8531200124192525 1.0 18.027284447839335 -7.22062497815397 3.2134768946361505 0.8682772093617763 0.9620968188704718 0.13362443605157126 0.09393385938702571 0.49380450053374275 10.357834874956133 0.04201921804921177 0.029910454242087627 6.016930870580869e-08 7.22062497815397 0.0938196095086955 VVPGQFDDADSS(ph)DSENRDLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVPGQFDDADSSDSENRDLK 20 1 E9PFQ8;Q9BRS2 E9PFQ8 RIOK1 Serine/threonine-protein kinase RIO1 1 VVPGQFDDADS(0.204)S(0.784)DS(0.012)ENRDLK 72.316 0.0015800999999999999 5177700.0 11325.0 8828.2 10791.0 16828.0 18164.0 16701.0 16624.0 19510.0 18038.0 14106.0 True False 13242.098821054164 9704.605352458762 11048.29836509539 15885.18171711211 14604.89459136502 15825.170159569798 15049.254372662588 18997.88317255372 18301.77162545666 16663.30613696545 0.7946861632505348 0.5823937502372543 0.6630315901468155 0.9533031192335134 0.8764703997705412 0.9497016996203201 0.9031373635558257 1.1401028713269155 1.0983277553100028 1.0 14.024387051212976 -6.242123210971408 0.6798022096438907 1.0649570832476671 0.6390976965488253 0.6991927585304454 0.09191002683240843 0.4704557641092122 0.46160569870773943 0.060427863914439724 0.11482367616738771 5.726335496554829e-07 6.242123210971408 -0.4258593866988418 VVPGQFDDADSS(ph)DSENRDLK ddPTM_PC-9_Lapatinib_30min_R1 2 VVPGQFDDADSSDSENRDLK 20 1 E9PFQ8;Q9BRS2 E9PFQ8 RIOK1 Serine/threonine-protein kinase RIO1 1 VVPGQFDDADS(0.116)S(0.884)DSENRDLK;VVPGQFDDADS(0.144)S(0.856)DSENRDLK 121.92 4.3667e-06 60026000.0 281244.0 184789.0 235600.0 204912.0 209025.0 192003.0 149353.0 173996.0 204908.0 153896.0 True False 277233.4089861669 184361.13242390205 216229.8774423002 219981.91204639338 196730.56045896135 183791.4792708536 157085.76755015852 182080.48936362707 181829.10326310148 180496.7185464698 1.5359470865659628 1.021409884393202 1.1979712383891938 1.2187585116111566 1.0899398174283819 1.018253853870122 0.8702970824908154 1.0087745130765329 1.007381766978155 1.0 17.461613083406498 -6.481167077158589 1.5993727880922965 0.9690090103538935 1.2344633767455162 0.5026802176639873 0.12341717318229696 0.3368458629587347 1.7439232263149456 0.04718432066746312 0.0535829997010883 3.3024246922167364e-07 6.481167077158589 0.2654543663916227 VVPGYGHAVLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVPGYGHAVLR 11 0 A0A0C4DGI3;B4DJV2;O75390;H0YIC4 A0A0C4DGI3 CS Citrate synthase;Citrate synthase, mitochondrial 0 87.149 0.008838 4170200.0 14103.0 30376.0 17757.0 20932.0 17290.0 16139.0 19502.0 17897.0 14339.0 13699.0 False True 16490.35935305314 33391.52853200964 18180.394223797506 19759.24790245964 13902.148617303508 15292.642428914261 17654.62937774698 17427.22271343896 14548.680748277146 16182.520258775661 1.0190229389090701 2.0634319004730837 1.1234587649558734 1.2210241412640497 0.8590842708671708 0.9450099356817535 1.0909690885863719 1.0769164774558715 0.8990367702699154 1.0 13.982148689523205 -5.495863624221316 23.372022704608554 1.0227916038014113 1.5542822572159205 0.4029697540313937 0.25323793201996425 273.29159566731965 236435.61872247187 0.06144583771571992 0.12717372701195162 3.192540209086715e-06 5.495863624221316 0.5314906534145092 VVPGYGHAVLR ddPTM_PC-9_Lapatinib_30min_R1 2 VVPGYGHAVLR 11 0 A0A0C4DGI3;B4DJV2;O75390;H0YIC4 A0A0C4DGI3 CS Citrate synthase;Citrate synthase, mitochondrial 0 ; 106.88 0.0019966 4784900.0 42916.0 92037.0 35295.0 50199.0 33285.0 34741.0 28816.0 30204.0 44861.0 38756.0 False True 42304.00997016947 91823.89398123635 32393.18134263997 53890.80191895498 31327.241740827794 33255.20841522645 30307.95148222915 31607.388105123067 39808.28177272724 45454.922960876065 0.9306804899126405 2.0201088903015183 0.712644070929818 1.185587795745245 0.6891935944494232 0.7316085090244209 0.6667693949963526 0.6953567632779437 0.8757749255672703 1.0 15.472148932420366 -5.289956395590614 24.862164797428917 0.8085471343043301 1.4753948942710988 0.450218640288216 0.2896611835080121 467.9328012341675 407959.99018071225 0.07085427962617408 0.14753926156512098 5.129128793277575e-06 5.289956395590614 0.6668477599667687 VVPQQITHT(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 2 VVPQQITHTSPR 12 0 H7BXF5;A0A2R8YDB8;Q9H0E3;Q9H0E3-3 H7BXF5 SAP130 Histone deacetylase complex subunit SAP130 1 VVPQQITHT(0.719)S(0.28)PR;VVPQQIT(0.004)HT(0.886)S(0.11)PR 156.2 0.00015562 35100000.0 96519.0 107527.0 149105.0 209970.0 158246.0 140916.0 125165.0 170633.0 122131.0 122591.0 True False 127210.03428008335 142282.99994491003 147127.77027652375 161564.66050416208 136276.27442479102 132104.50024357936 136304.44252326607 144265.59060626494 128586.59532462189 118299.12640379654 1.0753252213027402 1.202739227838827 1.2436927875048283 1.3657299543589616 1.151963489228417 1.116698865490014 1.1522015983280471 1.2194983597244473 1.086961495266758 1.0 16.85207989437348 -6.49998970616642 24.538382593648418 1.1314690464885857 1.2266616925606622 0.2533438284068873 0.08412326713086965 958.3962987584399 1027457.3665896392 0.026679492948677427 0.030030767415807486 3.1623526147144487e-07 6.49998970616642 0.09519264607207645 VVPQQITHT(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VVPQQITHTSPR 12 0 H7BXF5;A0A2R8YDB8;Q9H0E3;Q9H0E3-3 H7BXF5 SAP130 Histone deacetylase complex subunit SAP130 1 VVPQQIT(0.004)HT(0.498)S(0.498)PR;VVPQQIT(0.012)HT(0.494)S(0.494)PR 122.63 0.00082206 20370200.0 89176.0 74473.0 100703.0 96030.0 118943.0 105899.0 102264.0 92443.0 92388.0 71770.0 True False 104271.73549371521 81866.1872650893 103104.14143825414 90649.75043346081 95636.97298946965 100345.47001546495 92576.81359275528 90016.46920145482 93738.99971907586 84781.33286899261 1.2298902596263723 0.965615713916554 1.216118430192347 1.0692182744229357 1.1280428102876325 1.1835797647876407 1.0919480793703555 1.0617486910774538 1.1056561220136156 1.0 16.37145902709804 -8.84066451783558 0.6842908780938937 0.9998347885882121 1.1238462921095755 0.20243548057521554 0.07387381806997835 1.972076202424577 1.802500747688095 0.07360147406241617 0.026728204674419567 1.4432297817359444e-09 8.84066451783558 0.12401150352136348 VVPQQITHT(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 2 VVPQQITHTSPR 12 0 H7BXF5;A0A2R8YDB8;Q9H0E3;Q9H0E3-3 H7BXF5 SAP130 Histone deacetylase complex subunit SAP130 1 VVPQQIT(0.001)HT(0.5)S(0.5)PR;VVPQQITHT(0.5)S(0.5)PR 119.77 0.0010975 23665000.0 200679.0 196583.0 215470.0 181123.0 192469.0 189099.0 192568.0 185937.0 190514.0 161107.0 True False 197817.28065997822 196127.82414152383 197754.888338253 194443.38962861616 181148.35182861317 181011.6765812991 202538.2287975395 194576.31181639095 169056.30711864124 188954.1302884159 1.0469063595383374 1.0379652661847514 1.0465761612958857 1.0290507507394602 0.9586895589533388 0.9579662339479238 1.0718909848035028 1.0297542134664823 0.8946949551226903 1.0 17.527676528792767 -6.071210963570204 6.415161742243433 0.9900108410477082 1.0424497185129638 0.2690850608287826 0.04420180805019529 0.36904195048330996 27.008239356870686 0.01358547976997551 0.017757402940401196 8.487680759658393e-07 6.071210963570204 0.05243887746525555 VVPQQITHTS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVPQQITHTSPR 12 0 H7BXF5;A0A2R8YDB8;Q9H0E3;Q9H0E3-3 H7BXF5 SAP130 Histone deacetylase complex subunit SAP130 1 VVPQQIT(0.032)HT(0.251)S(0.716)PR 62.077 0.030133999999999998 5262200.0 23657.0 20150.0 25290.0 26000.0 30393.0 30656.0 28052.0 23198.0 25509.0 26051.0 True False 27661.662852951722 22150.358833289258 25893.00951285909 24543.30429313732 24437.70982797604 29048.34539319631 25394.71148110749 22589.07708031272 25882.020866713272 30773.840080397462 0.8988693897376767 0.719778837331346 0.8413967657339132 0.7975379162632059 0.7941066101640837 0.9439298221251149 0.8252045053449014 0.7340350447424879 0.8410396882253178 1.0 14.909416859596472 VVPS(ph)PLQFCAATPK ddPTM_PC-9_AZD4547_30min_R2 1 VVPSPLQFCAATPK 14 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 VVPS(0.999)PLQFCAAT(0.001)PK 93.243 0.0038303000000000005 28736000.0 33039.0 33205.0 53260.0 67172.0 74398.0 49424.0 43151.0 63481.0 46035.0 54500.0 True False 43544.714746108766 43937.866890834244 52553.73760053424 51686.53319705474 64069.12190295889 46333.5094669069 46991.35540543646 53671.47009825941 48468.31611768482 52591.97158850896 0.8279726625731414 0.8354481789466591 0.9992730071374035 0.9827837146220992 1.218230082801414 0.8809996672007349 0.8935081531665527 1.020525918256054 0.9215915405665238 1.0 15.68255496170078 -5.258496729059031 22.371446718132006 0.990956572616845 0.8317103275966331 0.33497687454953196 0.0889783698495633 67.20637621286318 510898.32124156976 0.02374001439655687 0.057178523416725434 5.5144635565045765e-06 5.258496729059031 -0.1592462450202119 VVPS(ph)PLQFCAATPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VVPSPLQFCAATPK 14 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 VVPS(1)PLQFCAATPK;VVPS(1)PLQFCAATPK 152.94 0.00025808 46867000.0 141202.0 136953.0 157114.0 174520.0 209330.0 180527.0 188472.0 160837.0 164420.0 142010.0 True False 165104.70973337692 150548.78874915434 160860.19361816288 164742.21020147405 168313.28918797834 171059.84632037932 170618.5677408847 156615.19917088753 166824.33144792033 167755.2888494582 0.9841997284600674 0.8974309530369277 0.958897896581473 0.9820388455788834 1.003326275686133 1.0196986783164053 1.0170681884968527 0.9335932133348853 0.9944505034212465 1.0 17.355998725670645 -5.705382038179278 3.1081404470867313 0.9933553103124475 0.9386495299995092 0.343774699087389 0.029800121209169476 0.26724552951895425 5.219697678203835 0.008665114466961282 0.015751307765641095 1.9706884072579e-06 5.705382038179278 -0.05470578031293827 VVPS(ph)PLQFCAATPK ddPTM_PC-9_Lapatinib_30min_R1 2 VVPSPLQFCAATPK 14 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 VVPS(1)PLQFCAATPK;VVPS(1)PLQFCAATPK 174.4 0.00013068 41704000.0 107924.0 87248.0 96296.0 89727.0 93200.0 89526.0 71626.0 78168.0 95410.0 70136.0 True False 106384.98396916215 87045.98261650122 88378.91459330943 96325.82290049743 87718.15923824992 85697.18167529913 75334.44381129033 81799.97064631355 84663.92108815913 82258.91414965456 1.2932942899734217 1.0581951332124016 1.0743992369327984 1.1710077126139884 1.0663666077412994 1.0417981146625555 0.9158210339882864 0.9944207444495796 1.0292370372666129 1.0 16.327884407365765 -6.678195274706067 2.021923637419243 0.9851538874642405 1.1373822524988333 0.537195839204774 0.0669211724566525 0.2694464729465703 2.261801184926376 0.025981016500758604 0.025268509079859593 2.0979963355162852e-07 6.678195274706067 0.1522283650345928 VVPSFLPVDQGGS(ph)LVGR ddPTM_PC-9_AZD4547_30min_R2 2 VVPSFLPVDQGGSLVGR 17 0 Q14126 Q14126 DSG2 Desmoglein-2 1 VVPSFLPVDQGGS(1)LVGR;VVPSFLPVDQGGS(1)LVGR 247.28 2.1679000000000004e-47 35971000.0 36384.0 61765.0 51794.0 58427.0 54225.0 38826.0 59619.0 64543.0 44124.0 41277.0 True False 47953.355165786576 81729.3283695943 51107.17771840161 44957.557838151544 46696.794741632046 36398.204082270335 64924.975502693276 54569.36240059163 46456.30455906863 39831.904793740985 1.2038930956001321 2.0518558877063016 1.283071396737029 1.1286820972020395 1.1723465142688778 0.913795216943524 1.6299741586271141 1.3699912842020656 1.1663088873010306 1.0 15.281636851739028 -5.493253902051525 24.628026733227767 1.2169674729530593 1.6377719491549896 0.28827944141503237 0.265527231734619 676.5411086323501 562427.5909610911 0.06743617707292858 0.1399954668606318 3.211782281909449e-06 5.493253902051525 0.4208044762019303 VVPSFLPVDQGGS(ph)LVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VVPSFLPVDQGGSLVGR 17 0 Q14126 Q14126 DSG2 Desmoglein-2 1 VVPS(0.006)FLPVDQGGS(0.994)LVGR;VVPSFLPVDQGGS(1)LVGR;VVPSFLPVDQGGS(1)LVGR 175.77 5.2474e-06 18137100.0 55024.0 50441.0 52232.0 51963.0 73053.0 35083.8 43750.5 41886.0 44429.0 30831.4 True False 64338.47642646219 55448.44912704429 53477.40897096311 49051.68157631902 58738.789065348414 33243.94376649989 39606.1359138098 40786.53688188546 45078.69007358988 36420.88875877191 1.7665268097271893 1.522435366536453 1.468316968461764 1.3468007851539594 1.6127774765299014 0.9127713490652571 1.0874566015160936 1.119866600511282 1.2377152675257754 1.0 15.152478507581613 -6.755024760318746 24.999981336360126 1.080047029378036 1.5271181218636785 0.7745055401643999 0.12709704039880412 77.95033100797639 303799.02821801597 0.04381913909069872 0.042810824500300756 1.7578233927722374e-07 6.755024760318746 0.4470710924856425 VVPSFLPVDQGGS(ph)LVGR ddPTM_PC-9_Lapatinib_30min_R1 2 VVPSFLPVDQGGSLVGR 17 0 Q14126 Q14126 DSG2 Desmoglein-2 1 VVPSFLPVDQGGS(1)LVGR;VVPSFLPVDQGGS(1)LVGR 177.12 4.2918e-06 28653000.0 46535.0 53917.0 28981.0 17294.6 26605.0 18816.7 13732.900000000001 14477.6 27424.0 7977.7 True False 45871.40236652617 53792.15849915061 26598.294049895136 18566.502577094347 25040.14620744252 18011.95360487008 14443.922366404244 15150.282149077266 24335.220332477482 9356.634815382939 4.902553457692983 5.7490924419442635 2.8427201205037678 1.984314119705705 2.6761914621563334 1.925046126119747 1.5437091060407169 1.6192020366306463 2.6008517819321897 1.0 13.191774031552907 -5.394687744928163 3.3928694107726174 1.9653487372059073 5.338562003764668 0.8724136550613544 0.513716825924963 0.07587325039902712 1.5932511142598074 0.13779943665148855 0.3225544939580071 4.030066895236213e-06 5.394687744928163 3.3732132665587606 VVS(ph)ETNDTK ddPTM_PC-9_AZD4547_30min_R2 2 VVSETNDTK 9 0 P05783 P05783 KRT18 Keratin, type I cytoskeletal 18 1 VVS(0.999)ET(0.001)NDTK;VVS(0.99)ET(0.008)NDT(0.002)K 115.33 0.0019855 12329000.0 52507.0 82349.0 70067.0 88226.0 89195.0 76666.0 69367.0 93486.0 78202.0 78566.0 True False 69203.13378655327 108966.70382753518 69137.86579903553 67886.8587781121 76811.81386777063 71872.0629004103 75540.52861831484 79039.88679456653 82335.59806745274 75815.42825362929 0.9127843155491312 1.4372629204573402 0.9119234355274632 0.8954227436532664 1.0131422539856674 0.9479872969914903 0.9963740937478476 1.0425303742946659 1.086000566955992 1.0 16.210203842722805 VVS(ph)ETNDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VVSETNDTK 9 0 P05783 P05783 KRT18 Keratin, type I cytoskeletal 18 1 VVS(0.997)ET(0.002)NDT(0.001)K;VVS(0.929)ET(0.008)NDT(0.063)K;VVS(1)ETNDTK 126.66 0.0013873 34973400.0 166885.0 174715.0 156629.0 200703.0 215108.0 195711.0 201493.0 230120.0 185568.0 173694.0 True False 195135.33437100443 192059.55054879026 160363.62937879024 189458.2615979055 172959.13156569836 185447.57063047506 182406.1243570079 224079.59383229475 188281.5809398353 205183.34723905276 0.9510291015169876 0.9360386850743185 0.7815625952916907 0.9233608094772602 0.8429491666503961 0.903813945555805 0.888990879676469 1.0920944455167043 0.9176260328791412 1.0 17.646554120437614 -7.701077690574772 14.896834541351273 1.003632184538837 0.8873243238505547 0.42629145113779277 0.06032839768215295 1.641176294689677 403.9894417196789 0.02735202315282824 0.01578889779087754 1.9903172609572606e-08 7.701077690574772 -0.11630786068828225 VVS(ph)LS(ph)LQT(ph)S(ph)S(ph)AHHRGGHGVPHGK ddPTM_PC-9_Lapatinib_30min_R1 1 VVSLSLQTSSAHHRGGHGVPHGK 23 1 H0Y2V6 H0Y2V6 CEP170 5 VVS(1)LS(1)LQT(1)S(1)S(1)AHHRGGHGVPHGK 50.883 0.0089098 1794300.0 0.0 0.0 621.19 0.0 0.0 470.63 490.63 0.0 0.0 0.0 True False 0.0 0.0 570.1181560627431 0.0 0.0 450.5022519921139 516.032420728973 0.0 0.0 0.0 0.0 VVS(ph)STSEEEEAFTEK ddPTM_PC-9_AZD4547_30min_R2 2 VVSSTSEEEEAFTEK 15 0 Q8N573-3;Q8N573-2;Q8N573-5;Q8N573-8;Q8N573 Q8N573-3 OXR1 Oxidation resistance protein 1 1 VVS(0.979)S(0.006)T(0.015)SEEEEAFTEK;VVS(0.83)S(0.136)T(0.005)S(0.029)EEEEAFTEK 165.78 0.00011661 12353500.0 28529.0 25905.0 31894.0 40480.0 31797.7 35493.0 27996.0 33788.0 30033.0 28987.7 True False 37600.628559936355 34278.284650114765 31471.06472083061 31147.961409765576 27383.138223254853 33273.61709916087 30487.589764561617 28566.840970999016 31620.48306641529 27972.849446169188 1.3441829954540319 1.2254126886887131 1.1250575234172469 1.1135069192613558 0.9789184428976686 1.1894968785068696 1.0898993262460366 1.0212345734020734 1.130399072402888 1.0 14.771739600559606 -4.882516423756414 1.1985673007877222 1.0753854552405102 1.4404184603283052 0.6835224804193262 0.05935174486008417 0.737770282198102 1.0234050250763214 0.01789794404016428 0.32276085312949593 1.3106404768112334e-05 4.882516423756414 0.365033005087795 VVS(ph)STSEEEEAFTEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VVSSTSEEEEAFTEK 15 0 Q8N573-3;Q8N573-2;Q8N573-5;Q8N573-8;Q8N573 Q8N573-3 OXR1 Oxidation resistance protein 1 1 VVS(0.901)S(0.051)T(0.006)S(0.041)EEEEAFT(0.001)EK;VVS(0.696)S(0.219)T(0.069)S(0.016)EEEEAFTEK;VVS(0.861)S(0.114)T(0.022)S(0.003)EEEEAFTEK 121.42 0.00054963 6809800.0 10521.5 13696.5 12778.0 15889.6 21577.2 21448.300000000003 25216.7 24409.100000000002 22587.000000000004 21265.699999999997 True False 12302.582140902554 15056.198002984926 13082.675980834862 14999.357226778258 17349.302553226215 20323.513390425775 22827.991622901875 23768.386988579245 22917.29214459417 25121.003070811414 0.4897329181571243 0.599347006986318 0.5207863692368192 0.5970843275842876 0.6906293711410239 0.8090247564214529 0.9087213420003187 0.9461559684372716 0.9122761571261547 1.0 14.61660645111949 -6.743412074760569 1.0198835035131504 0.9592246480389804 0.5322860364258528 0.9685221663637966 0.0320241989655426 0.07865265633777131 0.17551985156382208 0.017111370393426393 0.01584125030655338 1.8054602252066973e-07 6.743412074760569 -0.4269386116131276 VVS(ph)STSEEEEAFTEK ddPTM_PC-9_Lapatinib_30min_R1 2 VVSSTSEEEEAFTEK 15 0 Q8N573-3;Q8N573-2;Q8N573-5;Q8N573-8;Q8N573 Q8N573-3 OXR1 Oxidation resistance protein 1 1 VVS(0.5)S(0.5)TSEEEEAFTEK;VVS(0.53)S(0.238)T(0.183)S(0.048)EEEEAFTEK 261.45 9.697499999999999e-51 7113400.0 19468.3 18300.5 18692.7 18285.8 32345.4 38020.0 42321.0 33676.7 42205.0 40823.0 True False 19190.678471951032 18258.12631662936 17155.85836190866 19630.598731640614 30442.907165503133 36393.97322894878 44512.17430175662 35241.442424837696 37451.42846164715 47879.20115677173 0.40081450835227284 0.3813373213317919 0.3583154678319491 0.41000263699813605 0.6358273828718106 0.7601207277828914 0.9296766283967355 0.7360490896547336 0.7822066274460023 1.0 15.547111461305004 -6.498863238247978 1.783974788342363 0.840232448868385 0.37528608879408154 0.899806564525133 0.07174669023019001 0.10396214642581152 0.6666374049134542 0.026921058509000697 0.029872282194923987 3.1705657346692407e-07 6.498863238247978 -0.46494636007430346 VVSET(ph)NDTK ddPTM_PC-9_Lapatinib_30min_R1 1 VVSETNDTK 9 0 P05783 P05783 KRT18 Keratin, type I cytoskeletal 18 1 VVS(0.003)ET(0.923)NDT(0.074)K 84.71799999999999 0.031764999999999995 5005700.0 28184.0 30054.0 30367.0 20053.0 27346.0 24613.0 29404.0 28002.0 25897.0 20749.0 True False 27782.090991687397 29984.41180951224 27870.342480009866 21527.764514847004 25737.562044304566 23560.35936570532 30926.395245123047 29303.075146326846 22980.20715250035 24335.437003695388 1.1416310702564587 1.2321295814395707 1.1452575302336956 0.884626173410322 1.0576165959294779 0.9681502478105337 1.2708378830602798 1.2041318650606978 0.9443104370392343 1.0 14.570771061599741 -5.535463018248611 24.99338710450375 1.0584476856770295 1.1873336900507576 0.21125724734848916 0.1119109275355898 365.018186568461 724952.8519301667 0.03207298709692102 0.05559447539211759 2.9143182889847534e-06 5.535463018248611 0.1288860043737281 VVSETNDTK ddPTM_PC-9_AZD4547_30min_R2 1 VVSETNDTK 9 0 P05783 P05783 KRT18 Keratin, type I cytoskeletal 18 0 89.029 0.044516 5120200.0 20616.0 18026.0 17524.0 22743.0 22151.0 19250.0 17611.0 21002.0 22476.0 28670.0 False True 27171.4591605611 23852.55198235743 17291.620310021815 17499.952725847306 19075.71600409205 18046.29445690269 19178.344882972397 17756.623477948426 23664.03547433659 27666.272026468836 0.9821149425034807 0.8621527309330743 0.6250072396265967 0.6325374343570676 0.6894935459986065 0.6522850075224254 0.6932030764616252 0.6418148227907372 0.8553387840507304 1.0 14.755840636389651 -8.524779087897347 4.409884521669873 0.9996495812238335 0.7170499943948113 0.39575450004729185 0.10877583429230285 0.1779196418637943 11.53719392388935 0.11299558460213928 0.02950491140401095 2.9869015765443977e-09 8.524779087897347 -0.2825995868290222 VVSETNDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VVSETNDTK 9 0 P05783 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ; 128.27 0.006153499999999999 12995000.0 39602.0 49514.0 52029.0 51480.0 77756.0 72956.0 46664.0 80551.0 73998.0 73703.0 False True 46305.83642484651 54429.42269337387 53269.5686810813 48595.7425004119 62520.269976116455 69130.05892830214 42243.64810189649 78436.62160083924 75080.08075953761 87064.77046737306 0.531855033629237 0.6251601239076479 0.6118383864693436 0.5581562122032221 0.7180891839546686 0.7940072495132594 0.48519794947058426 0.9008996541285643 0.8623474265940133 1.0 16.409801450227405 -8.103223538897138 0.5878293879160655 1.0157288922008343 0.5928314541571772 0.63314795061496 0.1000791630702366 0.49623085643069054 0.3974146393121067 0.10004855260284191 0.05057214203966761 7.884541821232713e-09 8.103223538897138 -0.4228974380436571 VVSETNDTK ddPTM_PC-9_Lapatinib_30min_R1 4 VVSETNDTK 9 0 P05783 P05783 KRT18 Keratin, type I cytoskeletal 18 0 ;;; 125.71 0.0065321 99589000.0 174297.0 126705.0 134822.0 133324.0 164884.0 128083.0 180301.0 324097.0 227805.0 161496.0 False True 171811.49281784464 126411.62235723228 123737.45558797027 143129.09171582584 155185.8472944166 122605.18866605608 189636.10356043128 339155.72979426826 202147.20200700223 189410.3684201063 0.9070859966692641 0.6673954726536154 0.653277096814069 0.7556560546800161 0.8193102024394948 0.6472992460165728 1.0011917781598116 1.7905869283883733 1.0672446481844438 1.0 17.531155781266577 -7.52759664398301 24.993577465636054 1.336527461838527 0.7455917270187147 0.568561861723807 0.2116242249538878 82.83089958313835 438795.2496215768 0.09215724554026553 0.05345772522722761 2.9675862900515848e-08 7.52759664398301 -0.5909357348198123 VVSISSEHLEPIT(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 1 VVSISSEHLEPITPTK 16 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 VVSISSEHLEPIT(0.936)PT(0.064)K 138.46 3.3044000000000004e-05 15717000.0 33455.0 32633.0 120360.0 165320.0 125230.0 144740.0 72188.0 164370.0 91053.0 128260.0 True False 44092.99409277124 43180.979076903895 118763.94775817293 127208.02816853866 107843.97612714772 135689.38491907017 78612.59215331393 138970.3933468421 95865.87569161625 123769.65643930572 0.356250436183392 0.3488817883087445 0.959556252920622 1.0277804094165766 0.8713280720790588 1.096305741024737 0.6351523823762414 1.1228147297555966 0.7745507133941755 1.0 16.917298138986922 -5.260271675291551 24.975671003089655 0.9362802329000421 0.3525660498966295 0.736852666636068 0.1394481646645317 43.874226872807355 938384.788208374 0.033262669546999066 0.07856623775782555 5.4919721305509945e-06 5.260271675291551 -0.5837141830034127 VVSISSEHLEPIT(ph)PTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VVSISSEHLEPITPTK 16 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 VVSISSEHLEPIT(0.942)PT(0.058)K;VVSISSEHLEPIT(0.915)PT(0.085)K 128.1 4.6508e-05 17120300.0 47387.0 84389.0 179059.0 192356.0 231681.0 193207.0 183807.0 156394.0 170931.0 110548.0 True False 55408.68316408775 92766.5822125282 183328.4456450386 181578.91694656623 186284.77118597386 183074.884798515 166395.47031255942 152288.82321314013 173430.54250531847 130589.47730251333 0.4242966914993644 0.7103679724334329 1.4038531237884835 1.3904559593720922 1.426491437395382 1.4019114600973408 1.2741874288010262 1.1661645820080877 1.3280590908834322 1.0 16.99467912587631 -5.121183001893604 3.463620551568411 1.3155311273116113 0.4680048033438512 0.8415832614077834 0.12908925721248402 0.08446643048845162 1.8085671447360085 0.03389841287335605 0.11528910661021885 7.565140499008515e-06 5.121183001893604 -0.8475263239677601 down VVSISSEHLEPIT(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 1 VVSISSEHLEPITPTK 16 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 VVSISSEHLEPIT(0.813)PT(0.187)K 80.316 0.017134 7370100.0 42701.0 48098.0 118990.0 59222.0 104760.0 120900.0 79330.0 91658.0 130090.0 56234.0 True False 42092.07590959566 47986.632036132316 109207.1015146829 63577.38343880063 98598.22276608448 115729.38883166522 83437.31923532892 95916.76529397993 115437.8942915692 65953.971972905 0.6382038056311119 0.7275775908666431 1.6558078042600226 0.9639659528757311 1.494955039350629 1.7546993057402032 1.2650840690778469 1.4542985422225085 1.7502796395491242 1.0 16.00917192565339 -5.244992765116282 20.386401680129147 1.4267953746016937 0.6828877057064534 0.5532217274300708 0.26391698064743985 51.46222192533639 63785.545416701614 0.06524556315147803 0.1705061596964535 5.688624074070019e-06 5.244992765116282 -0.7439076688952403 VVSISSEHLEPITPT(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 VVSISSEHLEPITPTK 16 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 VVSISSEHLEPIT(0.412)PT(0.588)K 153.68 6.8389e-05 16802000.0 26024.0 30445.0 126200.0 177990.0 159570.0 140570.0 85153.0 157640.0 109680.0 129490.0 True False 34299.09066717319 40285.75086557593 124526.50554238493 136957.1554180875 137416.45987869464 131780.13567827563 92731.4520367808 133280.36020682714 115477.46088384226 124956.5945136887 0.27448803963216045 0.3223979576457065 0.9965580930484093 1.0960378357869234 1.0997135478403341 1.0546072913649982 0.7421093092179484 1.0666132565914845 0.9241405892443073 1.0 16.931067515286372 -5.255227883826082 6.142245079825472 1.001022201972446 0.2915917300475679 0.8872056845136036 0.09972972277403565 0.04374861042291193 7.8799082475247895 0.02708021084822764 0.06614472728598352 5.5561263864785624e-06 5.255227883826082 -0.7094304719248781 VVSPT(ph)KEQVSDTEDKQR ddPTM_PC-9_Lapatinib_30min_R1 1 VVSPTKEQVSDTEDKQR 17 2 O60303 O60303 KIAA0556 Uncharacterized protein KIAA0556 1 VVS(0.067)PT(0.914)KEQVS(0.016)DT(0.003)EDKQR 98.676 0.011054999999999999 12254000.0 47425.0 38494.0 35047.0 31441.0 34371.0 35020.0 36022.0 36745.0 35102.0 29200.0 True False 46748.71080332013 38404.86950806433 32165.570945332296 33753.27602410135 32349.365355985978 33522.27623560721 37887.042903000336 38452.30684421753 31148.443119553125 34247.18109344569 1.3650382107585204 1.121402354350687 0.9392180587817263 0.9855782270664356 0.9445847606469743 0.9788331525488032 1.1062820849290644 1.122787500066002 0.9095184515935063 1.0 15.063697623392734 -4.837960983058981 2.8690276424565377 1.0039441545482495 1.405334358281667 0.7431931128904492 0.0656009004589259 0.18973972006501147 2.3923469339136423 0.018013970777482284 0.16921309156352757 1.4522420809042234e-05 4.837960983058981 0.4013902037334176 VVSQS(ph)QPGSR ddPTM_PC-9_Lapatinib_30min_R1 2 VVSQSQPGSR 10 0 Q7Z460-4 Q7Z460-4 CLASP1 CLIP-associating protein 1 1 VVS(0.016)QS(0.984)QPGSR;VVS(0.039)QS(0.764)QPGS(0.197)R 85.67200000000001 0.011755 10069800.0 19653.0 22397.0 24022.0 21046.1 24732.0 27325.0 22148.0 27051.0 24404.0 19014.1 True False 19372.744616081192 22345.141122567587 22047.003887601568 22593.900401731462 23277.31238498282 26156.373447686103 23294.715069003698 28307.888214530667 21655.36453448732 22300.661850304306 0.8687071597301871 1.0019945270038106 0.9886255410532008 1.0131493205625712 1.0437946883027234 1.1728967338845677 1.0445750545599088 1.2693743533062176 0.9710637594458578 1.0 14.444798907362404 -5.239447912432249 0.6960248734575547 1.103275691442387 0.8433143501534252 0.3453668803011848 0.08514381864909291 1.9077886512494795 1.0544900064065863 0.0383072151796388 0.3557129735153892 5.761719182040467e-06 5.239447912432249 -0.25996134128896176 VVSQSQPGS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 VVSQSQPGSR 10 0 Q7Z460-4 Q7Z460-4 CLASP1 CLIP-associating protein 1 1 VVSQS(0.017)QPGS(0.983)R 79.089 0.019504 21658000.0 15552.0 14808.0 19024.0 33962.0 27314.0 23021.0 15358.0 20252.0 19454.0 22410.0 True False 20497.212498304536 19594.396413777245 18771.729329939226 26132.585607669433 23521.922573959204 21581.493230771768 16724.832247611717 17122.518744662946 20482.29872387185 21625.432721073124 0.9478290105303103 0.906081125243024 0.8680394779636905 1.208419084359143 1.087697197894127 0.9979681567130659 0.7733871716386065 0.7917769306866971 0.9471393700211447 1.0 14.40044138065952 -7.180299935477603 8.79769790677912 0.8608847374544675 1.00573514637087 0.23198782872607648 0.10922855638929108 0.5350876799410902 54.25034273453421 0.04488406091965587 0.03474499001814597 6.602373128281349e-08 7.180299935477603 0.14485040891640244 VVSQSQPGS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VVSQSQPGSR 10 0 Q7Z460-4 Q7Z460-4 CLASP1 CLIP-associating protein 1 1 VVSQSQPGS(1)R;VVSQSQPGS(1)R;VVSQSQPGS(1)R;VVSQS(0.001)QPGS(0.999)R 112.02 0.001511 44021000.0 48024.0 57256.0 85454.0 65316.0 103666.0 95692.0 79978.0 78423.0 78588.0 50456.8 True False 56153.51468276424 62939.99728827839 87491.54744609949 61656.55627732911 83353.39147260762 90673.74306386153 72401.90484942312 76364.47934603709 79737.20082611083 59604.21842419101 0.9421063838658396 1.0559654828513534 1.4678750893676697 1.034432761764143 1.3984478561466676 1.5212638544902155 1.2147110852818102 1.2811925290684416 1.3377778106012146 1.0 15.863126819033768 -5.071616569886943 5.790863195437628 1.2930261957079663 0.9670432457375412 0.34159941507633396 0.15990674969245905 0.1980589624496251 11.976448705590256 0.0392881782430585 0.11138711754647414 8.479757449665857e-06 5.071616569886943 -0.3259829499704251 VVSQSQPGS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 2 VVSQSQPGSR 10 0 Q7Z460-4 Q7Z460-4 CLASP1 CLIP-associating protein 1 1 VVSQSQPGS(1)R;VVSQSQPGS(1)R 78.529 0.020271 21987500.0 23375.5 25272.0 27915.0 25912.4 27659.0 20428.0 25529.6 24940.0 32539.0 23387.0 True False 23042.161083458308 25213.484236707052 25619.93645501615 27818.084337232387 26032.151999686226 19554.34205999384 26851.397770707837 26098.80344794627 28874.11516913962 27429.411788781345 0.8400530518442461 0.9192134498129994 0.9340315662727675 1.0141699191890805 0.9490597975685866 0.7128968791081253 0.9789272178884304 0.9514897238379973 1.0526698637026244 1.0 14.743436064130568 -7.843458329286794 2.3396111257125596 1.0184141981873585 0.9046303602304384 0.26779771106186834 0.07904470546326742 0.4580032908030292 4.902552506976908 0.05862615332815008 0.023345687584628898 1.4339752999057134e-08 7.843458329286794 -0.11378383795692004 VVSS(ph)TSEEEEAFTEK ddPTM_PC-9_AZD4547_30min_R2 2 VVSSTSEEEEAFTEK 15 0 Q8N573-3;Q8N573-2;Q8N573-5;Q8N573-8;Q8N573 Q8N573-3 OXR1 Oxidation resistance protein 1 1 VVSS(0.782)T(0.217)S(0.001)EEEEAFTEK;VVS(0.055)S(0.888)T(0.055)S(0.002)EEEEAFTEK 316.12 1.7176999999999993e-139 19248600.0 45302.0 46636.0 63500.0 75228.0 72068.0 59437.0 57700.0 65534.0 52762.0 64287.0 True False 59707.093659863196 61710.17498331417 62657.94850983704 57885.34686101395 62062.60218423125 55720.39499402208 62835.188220288845 55407.22612150615 55550.891604242155 62036.33169743989 0.9624536465351188 0.9947424887126397 1.0100202058275924 0.9330878418686829 1.000423469377904 0.898189713501734 1.0128772366287726 0.8931415608475234 0.8954573889889531 1.0 15.920825759695568 -6.5221584266767465 0.9706851055171501 0.9357391776949107 0.9859067341079095 0.11680184751817768 0.04499770718346075 1.0237410150605106 2.0888295153802976 0.02296948572345409 0.027064634920565378 3.004979913324255e-07 6.5221584266767465 0.05016755641299886 VVSS(ph)TSEEEEAFTEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVSSTSEEEEAFTEK 15 0 Q8N573-3;Q8N573-2;Q8N573-5;Q8N573-8;Q8N573 Q8N573-3 OXR1 Oxidation resistance protein 1 1 VVS(0.226)S(0.774)T(0.001)SEEEEAFTEK 199.33 5.847799999999999e-10 11476000.0 19557.0 22150.0 24568.0 24585.0 28773.0 27705.0 33401.0 33495.0 30776.0 26668.0 True False 22867.613831642928 24348.90561574972 25153.794294658852 23207.58215564543 23135.13719870874 26252.101028134915 30237.015477701087 32615.791740886067 31226.04077752824 31502.697296228143 0.7258938374899376 0.7729149471485112 0.7984647809084763 0.7366855586179949 0.7343859156301115 0.8333286759949318 0.9598230650973941 1.0353333060401528 0.9912180053632097 1.0 14.943187738615826 -7.2065603192260665 2.2651443336403143 1.0095845832910026 0.756543810868389 0.9584118730073251 0.024005265871682304 0.0583378574094493 0.5861877458085827 0.011632510575201706 0.007923442829755257 6.214979218176907e-08 7.2065603192260665 -0.2530407724226137 VVSS(ph)TSEEEEAFTEK ddPTM_PC-9_Lapatinib_30min_R1 2 VVSSTSEEEEAFTEK 15 0 Q8N573-3;Q8N573-2;Q8N573-5;Q8N573-8;Q8N573 Q8N573-3 OXR1 Oxidation resistance protein 1 1 VVSS(0.817)T(0.183)SEEEEAFTEK;VVS(0.042)S(0.478)T(0.478)S(0.002)EEEEAFTEK 233.97 8.129499999999999e-32 8231200.0 24597.2 19983.4 24539.0 24896.0 38218.0 49538.0 50640.0 50142.0 55112.0 47498.0 True False 24246.43941742595 19937.12966507643 22521.498143279292 26726.934890621404 35970.09237947897 47419.375218718174 53261.891416577004 52471.780372370595 48904.706204911694 55707.96601289331 0.4352418720836844 0.3578865123250432 0.40427787541312876 0.47976863639996475 0.6456902837047378 0.8512135447153683 0.9560911163809108 0.9419080273048612 0.8778763560240731 1.0 15.765596021397796 -6.5447492232559075 1.435189258005447 0.945133000082144 0.3926250698172289 0.9798235562962502 0.03463069733141492 0.050373257473116925 0.21367100722019575 0.01447247338377583 0.015758788842825944 2.852665020046303e-07 6.5447492232559075 -0.5525079302649151 down VVSS(ph)VSSSPR ddPTM_PC-9_AZD4547_30min_R2 1 VVSSVSSSPR 10 0 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 VVS(0.006)S(0.444)VS(0.211)S(0.104)S(0.235)PR 102.52 0.0031831 14104000.0 102720.0 80546.0 128550.0 183770.0 143340.0 142200.0 113910.0 143930.0 121300.0 141350.0 True False 135382.82329127064 106580.91933712206 126845.34300692202 141404.6657181972 123439.71522850219 133308.2115206004 124047.76932709009 121688.92568236921 127711.67036114211 136401.3795235916 0.9925326544652373 0.781377136429094 0.9299417898114675 1.0366806128506951 0.9049740967403661 0.9773230445777403 0.9094319262778067 0.8921385260720346 0.9362930991401993 1.0 17.057498709867666 VVSSEGGRPS(ph)VDLSFQPSQPLSK ddPTM_PC-9_AZD4547_30min_R2 1 VVSSEGGRPSVDLSFQPSQPLSK 23 1 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4;A0A2R8Y670 P49815 TSC2 Tuberin 1 VVS(0.199)S(0.169)EGGRPS(0.632)VDLSFQPSQPLSK 55.972 0.030825 0.0 8877.5 6183.7 8757.6 12114.0 10413.0 9346.2 8098.9 11929.0 9166.8 8767.3 True False 11700.360336528976 8182.460096155754 8641.468501885809 9321.304459434292 8967.334691463611 8761.780636524882 8819.686410351773 10085.647151149737 9651.33833360689 8460.35949555843 1.3829625493658397 0.967152767025022 1.0214067743128952 1.1017622199538737 1.0599235997207135 1.035627462535687 1.0424718258109462 1.1921062168155572 1.140771658541662 1.0 13.046503251960054 -4.75010539650477 24.99822794887891 1.06678018009665 1.382963239524332 0.6953272037647897 0.06360620534997179 310.2305059169024 684200.8482106066 0.016839823673098536 0.25636673910853386 1.7778479016926834e-05 4.75010539650477 0.316183059427682 VVSSEGGRPS(ph)VDLSFQPSQPLSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVSSEGGRPSVDLSFQPSQPLSK 23 1 P49815;P49815-4;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDR3;A0A2R8Y6C9;A0A2R8YGU4;A0A2R8Y7X5;A0A2R8YDZ2;H3BMQ0;A0A2R8Y5F1;X5D2U8;P49815-5;P49815-3;P49815-2;P49815-6;P49815-7;H3BQK4;A0A2R8Y670 P49815 TSC2 Tuberin 1 VVS(0.165)S(0.165)EGGRPS(0.66)VDLS(0.003)FQPS(0.006)QPLS(0.001)K 44.963 0.028449000000000002 3955100.0 9586.0 12740.0 11115.0 9546.4 12565.0 8998.2 8366.2 10135.0 8760.3 8400.9 True False 11208.720467869769 14004.74300427321 11380.023753872232 9011.546157846386 10102.978448607217 8526.318551574213 7573.692969957276 9868.966988920145 8888.402814640653 9923.91666851219 1.1294653957982295 1.41121126588146 1.1467270568665853 0.9080634651477189 1.0180434586540992 0.8591686968339379 0.7631757926775029 0.9944629039695188 0.8956547209674641 1.0 13.276693905580766 -5.634033050550238 3.521747976673174 0.9137644542097527 1.2737917062966366 0.6944003769748373 0.09597492917917605 0.11824416382271623 2.824681941469349 0.026362867770385552 0.049050292647170805 2.3225600388541367e-06 5.634033050550238 0.3600272520868839 VVSSIEQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VVSSIEQK 8 0 P63104;E7EX29;E7ESK7;E9PD24;E7EVZ2;E5RIR4 P63104 YWHAZ 14-3-3 protein zeta/delta 0 ;; 101.72 0.020729 11841200.0 87564.0 80535.0 95953.0 117185.0 110975.0 97689.0 91970.0 81462.0 83269.0 86236.0 False True 102386.85573216662 88529.98256272706 98240.88342377875 110619.50436889606 89230.24539070333 92566.01686834403 83257.93579486171 79323.70881612378 84486.65159552905 101869.90415619942 1.005074625133391 0.8690494341388801 0.9643759286662702 1.0858899425219903 0.875923523535318 0.9086689305843506 0.8172966931155686 0.7786765823838898 0.8293583104386135 1.0 16.636368367572373 -6.657019561302854 2.3313609228755183 0.8448325737677697 0.9709108686054128 0.3005097721313529 0.07760467320542662 0.3423351710509978 3.7995368219248062 0.028892757568013905 0.02849174478780231 2.2028272420339613e-07 6.657019561302854 0.1260782948376431 VVSSIEQK ddPTM_PC-9_Lapatinib_30min_R1 2 VVSSIEQK 8 0 P63104;E7EX29;E7ESK7;E9PD24;E7EVZ2;E5RIR4 P63104 YWHAZ 14-3-3 protein zeta/delta 0 ; 136.8 0.015499 31963000.0 174225.0 146753.0 157755.0 142869.0 156471.0 147002.0 148869.0 127703.0 153777.0 144460.0 False True 171740.51955104788 146413.20244497774 144784.99285191044 153376.06285701235 147267.68341382223 140715.0671383989 156576.70839838852 133636.5475827218 136457.0149164013 169429.7185191498 1.0136386995864417 0.8641530171014795 0.8545430761342268 0.9052488795799835 0.8691962939026974 0.8305217547917638 0.9241395769697358 0.7887432544345372 0.8053900821477091 1.0 17.370327424666513 -4.761107124876946 24.999832780725384 0.8655687604515099 1.0136388650459622 0.34549246747695417 0.058279897358202666 8.438063567122748 633977.211930606 0.013773560298052342 0.07817073738278314 1.733376383214632e-05 4.761107124876946 0.14807010459445236 VVSSVS(ph)SSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVSSVSSSPR 10 0 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 VVS(0.007)S(0.167)VS(0.56)S(0.246)S(0.02)PR 84.31 0.012625 16251000.0 70006.0 67522.0 64975.0 74966.0 83859.0 86001.0 87203.0 81269.0 72652.0 69655.0 True False 81856.63311847406 74225.13792264783 66524.2504190597 70765.89806305112 67427.43093686845 81490.95616389212 78942.50054495299 79135.77486162327 73714.39805591958 82282.90011132341 0.9948194947884355 0.9020724576093702 0.8084820822923926 0.8600316465184074 0.8194586098161771 0.9903753520311043 0.9594034779784003 0.9617523781315159 0.8958653372230292 1.0 16.32830502298072 -6.770929056879895 24.99994054671619 0.9589590963955583 0.8736210557360712 0.3757055014521622 0.05433235450081862 231.17667827034862 609016.2678867657 0.019901538401219443 0.0177774545354946 1.6946145974899802e-07 6.770929056879895 -0.08533804065948714 VVSSVS(ph)SSPR ddPTM_PC-9_Lapatinib_30min_R1 1 VVSSVSSSPR 10 0 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 VVS(0.001)S(0.121)VS(0.412)S(0.233)S(0.233)PR 104.07 0.0026576 11278000.0 107160.0 104570.0 112800.0 99128.0 102050.0 108320.0 101440.0 103690.0 125480.0 88243.0 True False 105631.87874926285 104327.8745897615 103526.01942059162 106418.2038013143 96047.61963801937 103687.40610625292 106692.06685026799 108507.81593895565 111347.1210370214 103495.68497359354 1.0206404139091823 1.0080408146134816 1.0002930986640246 1.028238074161898 0.9280350157837546 1.0018524553241839 1.0308842042785649 1.048428405171104 1.0758624484241166 1.0 16.65921109339841 -7.364814063556781 3.3457975615215307 1.045470696831422 0.9965611887398288 0.29961646437689027 0.030749940806294413 0.30280405129105337 6.385606481683365 0.014290894216274865 0.009169126719011622 4.3170386457855003e-08 7.364814063556781 -0.04890950809159322 VVSSVSS(ph)SPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVSSVSSSPR 10 0 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 VVS(0.001)S(0.02)VS(0.091)S(0.444)S(0.444)PR 94.465 0.0062919 15880000.0 91696.0 95379.0 96599.0 114030.0 113120.0 117530.0 126750.0 91054.0 113540.0 88201.0 True False 107218.32172144634 104847.59678214866 98902.28651374746 107641.26879024807 90954.94803871449 111366.51990025965 114743.32240946742 88663.92897968783 115200.30770342353 104191.14310126829 1.0290540878051007 1.0063004748901 0.9492389042859397 1.0331134258276296 0.8729623779087545 1.0688674352292813 1.101277123890876 0.8509737616901963 1.1056631521112588 1.0 16.66887311916495 VVSSVSS(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 VVSSVSSSPR 10 0 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 VVSS(0.008)VS(0.152)S(0.519)S(0.321)PR 106.16 0.0023566999999999998 13908000.0 131630.0 103060.0 122480.0 91759.0 106450.0 136910.0 100060.0 96034.0 137670.0 96698.0 True False 129752.93206201453 102821.37090198766 112410.16718647267 98507.262959051 100188.8202887524 131054.67845279796 105240.61720265988 100496.09022935358 122164.15487063065 113412.1204580143 1.144083467781115 0.9066171277526957 0.9911653774967327 0.8685779135530656 0.8834048766934286 1.1555614860522339 0.9279485894245356 0.8861141985838957 1.0771701858432001 1.0 16.791215305107237 VVSSVSSS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 VVSSVSSSPR 10 0 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 VVSS(0.001)VS(0.009)S(0.031)S(0.959)PR 119.03 0.0008238999999999999 26380000.0 59053.0 54829.0 86269.0 115510.0 102450.0 78802.0 76590.0 91641.0 68162.0 90829.0 True False 77830.62562129497 72551.40201046686 85125.01669283681 88880.95411171002 88226.58591572517 73874.49848274518 83406.36162551011 77479.98915068424 71764.90416451896 87649.10435619578 0.8879797026219497 0.8277483557119579 0.9712023564656022 1.0140543336359507 1.0065885620140802 0.8428437349744934 0.9515939978868049 0.8839792456499562 0.8187750997759741 1.0 16.41945172840675 -10.203846355875648 15.226615959660938 0.9999999996336473 0.9150678456632104 0.12961973187256703 0.06817124493998446 0.0 0.0 0.07048456663955262 0.017095018425338962 6.253939046673986e-11 10.203846355875648 -0.08493215397043685 VVSSVSSS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVSSVSSSPR 10 0 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 VVSS(0.002)VS(0.028)S(0.096)S(0.874)PR 113.67 0.0012735 16566000.0 89929.0 78269.0 90626.0 99253.0 137880.0 103480.0 119560.0 127410.0 104140.0 91427.0 True False 105152.20352128765 86039.0290581992 92786.86754101889 93692.17619256747 110863.4037798615 98053.3266338711 108234.4112605593 124065.62250205377 105662.85048647597 108001.99136426617 0.9736135620558436 0.7966429875168608 0.8591218214492904 0.8675041544054966 1.0264940708911972 0.9078844324560601 1.0021519963970777 1.1487345828986488 0.9783416875166606 1.0 16.72069838779653 -6.669805384521539 1.001319048563091 1.0424979870039988 0.8649447750199731 0.4492450015528696 0.07115077963240186 0.44731347160248325 0.9679120274195904 0.038825957206640775 0.03887285764097037 2.1389203649880552e-07 6.669805384521539 -0.17755321198402563 VVT(ph)DTDETELAR ddPTM_PC-9_Lapatinib_30min_R1 1 VVTDTDETELAR 12 0 P05198 P05198 EIF2S1 Eukaryotic translation initiation factor 2 subunit 1 1 VVT(0.936)DT(0.063)DET(0.001)ELAR 81.565 0.031944 4292400.0 24801.0 26379.0 31088.0 18407.0 29211.0 27748.0 23951.0 23680.0 30117.0 26256.0 True False 24447.333192053607 26317.921046220945 28532.06464315035 19760.712183951964 27492.86641103563 26561.282723747256 25191.06558685695 24780.259248090133 26724.906313930303 30794.314616079144 0.7938911288283234 0.8546357135832838 0.9265367649472682 0.6417000160683549 0.8927903333390095 0.8625385255328389 0.8180427426595013 0.8047024120209256 0.867851960568591 1.0 14.910376398251707 -8.649480736591437 3.92510701014274 0.9999809973965325 0.8262919546718359 0.3479321068807443 0.07229661507910522 0.8246371102394332 23.687857885412875 0.06800978338256305 0.017825461168520795 2.2413994622792823e-09 8.649480736591437 -0.17368904272469654 VVT(ph)SENEAGK ddPTM_PC-9_Lapatinib_30min_R1 1 VVTSENEAGK 10 0 P49321;P49321-3;P49321-4;E9PPR5 P49321 NASP Nuclear autoantigenic sperm protein 1 VVT(0.873)S(0.127)ENEAGK 172.21 1.6436e-19 0.0 159060.0 166900.0 130680.0 132990.0 163380.0 142030.0 139740.0 139150.0 132100.0 125820.0 True False 156791.77523196838 166513.5533043053 119935.99483938784 142770.5282416346 153770.3096174387 135955.70798810106 146975.0534469287 145615.41699205 117221.50692533102 147567.81935538855 1.062506554050011 1.1283866227181254 0.8127516918207296 0.9674909398627041 1.0420314557004644 0.9213100022890359 0.9959830950199767 0.9867694571088257 0.7943568417381414 1.0 17.171018616443106 -5.233453730021264 24.954543986073887 0.9455594641954819 1.095446626985179 0.3891227249640933 0.07762132147349339 735.7354011725586 656046.1322567947 0.019357079436568822 0.05119074271753803 5.841794425843454e-06 5.233453730021264 0.14988716278969716 VVTDTDETELAR ddPTM_PC-9_AZD4547_30min_R2 2 VVTDTDETELAR 12 0 P05198 P05198 EIF2S1 Eukaryotic translation initiation factor 2 subunit 1 0 ; 197.79 4.5391000000000006e-05 7660400.0 20666.7 19255.9 28474.0 38440.0 33110.0 31918.0 22187.2 35009.0 20991.4 25292.0 False True 27238.2807059356 25479.993105352063 28096.416155418912 29578.25189207978 28513.2480202017 29922.16241430753 24161.81781769831 29599.16347678773 22100.96254920756 24406.534778285648 1.1160240875394298 1.0439824144155632 1.1511841566471013 1.2118988689207688 1.168262855797529 1.2259897886417332 0.9899733017074975 1.212755671613077 0.9055346344730043 1.0 14.57497985643576 -8.266556768779273 24.99624119260867 0.9527673005935486 1.138383494784678 0.5022739111748957 0.07454272921517852 373.57981460475577 1824744.2240355646 0.06425136364597474 0.018618303289119554 5.41306486410451e-09 8.266556768779273 0.1856161941911294 VVTDTDETELAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVTDTDETELAR 12 0 P05198 P05198 EIF2S1 Eukaryotic translation initiation factor 2 subunit 1 0 157.78 0.002026 3875400.0 8598.7 8575.7 10378.0 11809.0 9788.2 8486.9 10096.0 9451.4 9912.4 8563.6 False True 10054.290077933641 9427.038821173128 10625.450878784173 11147.380015294562 7870.272475181626 8041.8320236664185 9139.633791289794 9203.310764586067 10057.350097581582 10116.112890579705 0.9938886790494762 0.9318835132763045 1.0503491799383509 1.101943022568994 0.7779937373485182 0.7949527758982512 0.9034728941984006 0.90976750300566 0.9941911687192772 1.0 13.30436742148241 -6.255130540789803 24.999264856391072 0.8874663704329989 1.0154589872093813 0.366660559623296 0.07842036670504314 588.7112947422734 2332812.413820516 0.02486248445328339 0.03132012011102717 5.557371879692806e-07 6.255130540789803 0.1279926167763824 VVTDTDETELAR ddPTM_PC-9_Lapatinib_30min_R1 2 VVTDTDETELAR 12 0 P05198 P05198 EIF2S1 Eukaryotic translation initiation factor 2 subunit 1 0 ; 169.58 0.00093001 17007600.0 33664.0 32419.0 34047.0 30749.0 40680.0 36142.0 33314.0 27422.0 37824.0 25500.0 False True 33183.945186778474 32343.935797317437 31247.787085220643 33010.38403565701 38287.28237995718 34596.29091111699 35038.83591334608 28696.126228932742 33563.86281562236 29907.641023385797 1.1095473949560524 1.0814606130930426 1.0448094873409421 1.1037441572153774 1.2801839620189053 1.1567709698021644 1.1715680245709794 0.9594914626163351 1.1222504238758797 1.0 14.868226501371575 -7.749456566073191 24.998813147973475 1.0306531924850106 1.1350470427495325 0.32968014840746573 0.07064598248742766 279.817802231604 583764.8307210583 0.036018686669929634 0.020589685756036626 1.7805059689078397e-08 7.749456566073191 0.10439385026452186 VVTS(ph)ENEAGK ddPTM_PC-9_AZD4547_30min_R2 2 VVTSENEAGK 10 0 P49321;P49321-3;P49321-4;E9PPR5 P49321 NASP Nuclear autoantigenic sperm protein 1 VVT(0.056)S(0.944)ENEAGK;VVT(0.01)S(0.99)ENEAGK 139.32 0.00011634 24304000.0 179524.0 166227.0 192324.0 184972.0 178745.0 191998.0 170856.0 211250.0 191876.0 177045.0 True False 236608.89766882884 219956.62700384602 189773.65809773086 142329.56318891209 153929.34211328728 179992.3347083841 186061.8530080707 178606.16654207194 202018.17363738242 170846.70843830422 1.3849192637754124 1.2874501886190934 1.1107832268612976 0.8330834377199009 0.9009792668547307 1.0535311821555082 1.0890572883074356 1.0454176622698574 1.182452828526894 1.0 17.382342927264105 -5.274032016308825 2.911619071338907 1.014957168221604 1.3592388584882624 0.6520834274342362 0.0929040960419178 0.17207215055757916 2.8974497875346072 0.027551084651477244 0.08110790697887 5.320690335452446e-06 5.274032016308825 0.34428169026665834 VVTS(ph)ENEAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VVTSENEAGK 10 0 P49321;P49321-3;P49321-4;E9PPR5 P49321 NASP Nuclear autoantigenic sperm protein 1 VVT(0.029)S(0.971)ENEAGK;VVT(0.23)S(0.77)ENEAGK 103.43 0.0028334 12832000.0 105225.0 135175.0 112316.0 123687.0 133270.0 90734.0 119920.0 90052.0 103890.0 80672.0 True False 123037.5142115162 148594.28065954673 114994.0394008022 116757.21838866439 107156.7001867 85975.7493119217 108560.3094543853 87688.23041798113 105409.19470942949 95297.19500079959 1.2910927148536098 1.5592723443570395 1.206688606100498 1.2251905041663056 1.1244475788169936 0.9021855187993761 1.1391763362339722 0.9201554192360581 1.106110150551074 1.0 16.54014612969734 -5.888424834848168 1.1897538234054632 1.0166580344322576 1.422952423588482 0.6784240426531043 0.10389259656444136 0.2658707176293871 0.75671434232514 0.03624814353217204 0.08114463882566372 1.2929304542931177e-06 5.888424834848168 0.4062943891562245 VVTS(ph)ENEAGK ddPTM_PC-9_Lapatinib_30min_R1 1 VVTSENEAGK 10 0 P49321;P49321-3;P49321-4;E9PPR5 P49321 NASP Nuclear autoantigenic sperm protein 1 VVT(0.213)S(0.787)ENEAGK 70.41199999999999 0.035844 17523000.0 174010.0 187210.0 145910.0 140770.0 190660.0 170010.0 166640.0 184330.0 150220.0 126740.0 True False 171528.5854904741 186776.52674714854 133913.84302888776 151122.6953949542 179445.75365198212 162739.06861266645 175267.803824218 192894.64472974898 133300.6417132719 148646.84012956568 1.1539336143369339 1.2565119217088485 0.900885904551781 1.0166559562465673 1.2071952117890368 1.094803417757266 1.1790886619012457 1.2976706707092824 0.896760681875797 1.0 17.181529269819208 -8.286653961984817 24.785578090386736 0.9483802946053094 1.132512588114489 0.31548572305468225 0.11166180332286299 1036.732225882003 1019081.5632385134 0.11165076613857784 0.028877428930253038 5.168280044968795e-09 8.286653961984817 0.1841322935091797 VVTVSS(ph)RSPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVTVSSRSPR 10 1 Q96RY5 Q96RY5 CRAMP1L Protein cramped-like 1 VVTVS(0.071)S(0.876)RS(0.053)PR 64.945 0.036781 0.0 13977.0 9197.9 9877.4 16933.0 16814.0 14995.0 16263.0 14853.0 13466.0 10157.0 True False 16343.030041666583 10111.006725196588 10112.914676248098 15984.298907526689 13519.417400308928 14208.635802811148 14722.45090607625 14463.124488054353 13662.914774830886 11998.383697232235 1.3621026343270355 0.8426973982778178 0.842856415617124 1.332204346091542 1.1267698834658506 1.1842124873943454 1.2270361806709347 1.2054227346797286 1.1387296088874554 1.0 13.550552452963146 -5.7626242046614635 24.999975048000987 1.182773613120276 0.9985666968862695 0.17191522150708782 0.15620041216416888 46.43621827076374 979851.1599975791 0.042198578536235216 0.06678187840819536 1.7273319070960542e-06 5.7626242046614635 -0.18420691623400642 VVTVSSRS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 VVTVSSRSPR 10 1 Q96RY5 Q96RY5 CRAMP1L Protein cramped-like 1 VVTVS(0.068)S(0.334)RS(0.597)PR 73.082 0.013628 1704900.0 11490.0 10207.0 13622.0 27023.0 20011.0 15829.0 8753.3 13866.0 12700.0 14890.0 True False 15143.580993153233 13506.213141236118 13441.363379543318 20793.264851188127 17232.818065003208 14839.210127704544 9532.326742610989 11723.328308981663 13371.296072436135 14368.705632163268 1.0539279863354891 0.9399742389463025 0.9354609749576772 1.447121639449831 1.1993298844141422 1.0327450855759817 0.6634088683168226 0.8158931367304145 0.930584592289614 1.0 13.810642485731227 -7.048324687978541 7.900679604316998 0.8378624964851975 1.1142293788544522 0.3806171586565251 0.15806389476819172 0.33875400282362045 50.48421125107793 0.06497209116549495 0.05072519256054368 8.946956215865547e-08 7.048324687978541 0.27636688236925466 VVVDPVVTEQPSTSS(ph)AAK ddPTM_PC-9_AZD4547_30min_R2 2 VVVDPVVTEQPSTSSAAK 18 0 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 VVVDPVVTEQPSTS(0.205)S(0.795)AAK;VVVDPVVTEQPS(0.001)T(0.007)S(0.083)S(0.909)AAK 319.11 9.948699999999998e-157 9745700.0 83322.0 91295.0 100537.0 122822.0 113728.0 131838.0 103325.0 126400.0 99227.0 104851.0 True False 109816.66279473572 120804.32337897031 99203.81369029124 94507.28548098398 97938.83028817574 123594.14901865655 112520.7248329523 106867.78438304365 104471.93664406464 101180.19840416039 1.0853572588983993 1.1939522286408464 0.9804666847363299 0.934049220811747 0.9679644024511879 1.2215250707946284 1.1120824687800337 1.0562124414518779 1.0325334234546124 1.0 16.62656744767682 -10.774102596741333 0.005567807454176774 1.018018074361868e-06 2.0704059816923137 0.03316312800404142 0.08925247568592512 116928.93996158407 113.23031310417572 21825.8125452891 20296.41415246717 1.6822765969245522e-11 10.774102596741333 2.0704049636742394 VVVDPVVTEQPSTSS(ph)AAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVVDPVVTEQPSTSSAAK 18 0 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 VVVDPVVTEQPSTS(0.021)S(0.979)AAK 229.02 3.4929e-35 3993000.0 26048.0 21787.0 22698.0 22196.0 22292.0 13667.0 23553.0 13778.0 15151.0 11375.0 True False 30457.411928549132 23949.86937473315 23239.206402644348 20952.43008040291 17924.042624460963 12950.278460621545 21321.8893310468 13416.342098997698 15372.554712124065 13437.197455549545 2.2666491304680694 1.7823559900760322 1.7294682525519178 1.5592857178525412 1.3339122747696437 0.9637633519535055 1.5867809788149603 0.9984479385213445 1.1440298293581463 1.0 13.713944651699581 -1.5228787452803445 0.2949153782825879 1.024494966414287 11.262795520598655 0.8170269155595052 0.172921442096343 21.428017592770114 0.30479608064819697 0.1772841351389387 115.06364251884824 0.02999999999999952 1.5228787452803445 10.238300554184367 up VVVDPVVTEQPSTSS(ph)AAK ddPTM_PC-9_Lapatinib_30min_R1 1 VVVDPVVTEQPSTSSAAK 18 0 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 VVVDPVVTEQPSTS(0.024)S(0.975)AAK 255.93 3.3093999999999996e-65 5821000.0 44552.0 44794.0 45744.0 46968.0 41787.0 47307.0 34349.0 21425.0 34070.0 25022.0 True False 43916.680310163814 44690.282245135175 41983.10489694642 50422.18340065493 39329.17081640292 45283.789888003164 36127.42314905219 22420.483715807903 30232.677826994874 29347.019360280756 1.496461353400752 1.5228218476463238 1.4305747504214266 1.7181364411030449 1.3401419181135765 1.5430456269535764 1.231042331949672 0.7639782234972912 1.0301788217686187 1.0 14.840926362526769 -7.513263203331155 3.621806134955502 0.9247345083406538 1.5049097660104835 0.8399705550130261 0.11280127132064045 0.0806671138259119 2.286439826573331 0.05230143386002078 0.03070199645836723 3.067162577051536e-08 7.513263203331155 0.5801752576698297 VVVS(ph)PTK ddPTM_PC-9_AZD4547_30min_R2 2 VVVSPTK 7 0 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 1 VVVS(0.913)PT(0.087)K;VVVS(0.996)PT(0.004)K 74.92 0.033477 10438600.0 84943.0 77630.0 82860.0 117645.0 118786.0 109557.0 106614.0 109899.0 95831.0 108675.0 True False 111953.10707584124 102722.37936260995 81761.2222602377 90523.7628471313 102294.61429561075 102706.3834709033 116102.43946131477 92916.63477778553 100896.43101713597 104870.32132809579 1.0675385147870993 0.9795181140070525 0.7796411913761636 0.8631971534054896 0.9754391232918347 0.9793655838011364 1.1071048318625663 0.8860145902203148 0.9621066259678259 1.0 16.678246922314578 -6.434123766807151 8.236074454814856 0.9862366859259357 0.9163977562042787 0.11231769551137716 0.08592719232957478 0.7529367339713503 63.6201249526886 0.028674143165903523 0.032480920471069465 3.680240778679596e-07 6.434123766807151 -0.06983892972165706 VVVS(ph)PTK ddPTM_PC-9_Lapatinib_30min_R1 2 VVVSPTK 7 0 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 1 VVVS(0.86)PT(0.14)K;VVVS(0.995)PT(0.005)K 114.89 0.0084641 380440000.0 823800.0 892420.0 936770.0 997390.0 974370.0 856680.0 863480.0 886370.0 846100.0 826560.0 True False 812052.4609335811 890353.6563201221 859752.386636771 1070741.3877955044 917059.4722851261 820041.7934186183 908186.7693599118 927553.9860527702 750803.308172009 969429.7946780283 0.8376598959425255 0.9184302578773439 0.8868640012475747 1.104506374441611 0.9459782207227335 0.8459011657373028 0.9368257240964449 0.9568036707194809 0.7744792993714097 1.0 19.886776897743353 -10.013886893715075 15.381574016976097 1.0000007797883803 0.9181663307444639 0.08577665874899942 0.08406339197458694 0.0 0.0 0.0822815469807913 0.019956206425942622 9.68530064332503e-11 10.013886893715075 -0.08183444904391646 VVVS(ph)PTKK ddPTM_PC-9_AZD4547_30min_R2 2 VVVSPTKK 8 1 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 1 VVVS(0.794)PT(0.206)KK;VVVS(0.884)PT(0.116)KK 87.806 0.016819 2329000000.0 6842500.0 5292900.0 6408200.0 7334600.0 7182500.0 6631600.0 7090400.0 7368900.0 6545000.0 7243500.0 True False 9018272.66715851 7003726.416699183 6323223.080956496 5643721.288440378 6185333.853974591 6216925.0036569135 7721431.864075132 6230205.825476351 6890955.338117683 6989907.269749794 1.290184879302601 1.0019770143459834 0.9046218836580987 0.807410037163826 0.8848949800439909 0.8894145177807845 1.1046544061451509 0.8913145174956467 0.9858435988041866 1.0 22.73684188581766 -2.890552636727488 8.657341813610829 0.9657009677042779 1.058356495405991 0.0 0.13197166929394286 0.0 0.0 0.03099588443707165 0.0 0.001286611305589177 2.890552636727488 0.09265552770171304 VVVS(ph)PTKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VVVSPTKK 8 1 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 1 VVVS(0.953)PT(0.047)KK;VVVS(0.787)PT(0.213)KK 74.84100000000001 0.03998 2086700000.0 6666700.0 6716700.0 5187300.0 7744500.0 8078600.0 6590300.0 7715800.0 7750800.0 6450200.0 5488400.0 True False 7795240.636673018 7383489.586876123 5310984.904944812 7310600.773007751 6495656.32271533 6244693.06643991 6984903.5664455155 7547349.712651411 6544521.972420477 6483403.473849489 1.2023377332777088 1.1388292609980375 0.8191661873838989 1.1275868920536452 1.0018898791221713 0.9631813123504642 1.0773513625395679 1.1641030429608923 1.0094269157885216 1.0 22.628319926541558 -5.015235061748401 24.580788674999564 1.0260074884224628 1.1864607348363156 0.3184112053741245 0.08974432909724714 586.4070080626958 946142.4503288122 0.022676145829011573 0.06490874489385973 9.655281457401839e-06 5.015235061748401 0.16045324641385283 VVVS(ph)PTKK ddPTM_PC-9_Lapatinib_30min_R1 2 VVVSPTKK 8 1 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 1 VVVS(0.851)PT(0.149)KK;VVVS(0.796)PT(0.204)KK 115.7 0.0053214 2451800000.0 7992000.0 7213500.0 7182300.0 7722900.0 7995100.0 6650700.0 6963800.0 7270300.0 7100700.0 6239200.0 True False 7878032.6144467015 7196797.583946132 6591799.01847976 8290867.828839184 7524843.936971375 6366265.064538921 7324351.489864914 7608104.67953503 6300944.392314141 7317637.406788577 1.076581439678638 0.9834864976050409 0.9008097357166868 1.1329979019113108 1.0283160422776034 0.8699891386573667 1.0009175206016778 1.0396941330376641 0.8610626684602807 1.0 22.80294650038953 VVWSMVSEHLEECIITTT(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VVWSMVSEHLEECIITTTK 19 0 A0A0A0MRA3;A0A0A0MTS7;Q8WZ42-3;Q8WZ42-10;Q8WZ42-9;Q8WZ42-5;Q8WZ42-11;Q8WZ42-4;Q8WZ42-7;Q8WZ42-2;Q8WZ42;Q8WZ42-8;Q8WZ42-13;Q8WZ42-12 A0A0A0MRA3 TTN Titin 1 VVWSMVSEHLEECIIT(0.152)T(0.152)T(0.696)K 62.19 0.015781 19812000.0 25474.0 23582.0 26012.0 29990.0 28425.0 23597.0 28191.0 22326.0 20013.0 15912.0 True False 29786.245065565883 25923.065111991426 26632.224731059345 28309.757528891838 22855.325300569824 22359.531779855595 25520.54439483463 21739.966156352362 20305.65226412376 18796.719640677304 1.5846512388846052 1.379127082147475 1.416854921505852 1.5061009617671646 1.215920955223987 1.1895443570626087 1.3577126691620456 1.1565829874541345 1.080276380788328 1.0 14.198193287672542 -6.100703662376931 0.21673731016264006 0.9392899848227605 1.7806600744550678 0.7815943483012684 0.08406716748257566 3.303190480186714 0.2510237951538726 0.20102146364379123 0.7839168021579833 7.930422724264389e-07 6.100703662376931 0.8413700896323073 VVYAFS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 VVYAFSPK 8 0 A7KAX9;A7KAX9-2;G3V174 A7KAX9 ARHGAP32 Rho GTPase-activating protein 32 1 VVYAFS(1)PK;VVYAFS(1)PK 86.898 0.01213 61971000.0 209796.0 199026.0 216210.0 280315.0 283849.0 256768.0 242888.0 234858.0 222552.0 228369.0 True False 276506.76397211326 263357.26233444305 213342.91413089584 215692.70757357808 244441.46594038774 240712.25636935048 264504.56146359595 198566.09259994377 234315.6443710873 220373.87082011407 1.2547166455946093 1.195047585970005 0.968095325171479 0.978758084027316 1.1092125624090865 1.0922903676082276 1.2002537346158644 0.9010419060162924 1.0632641859903327 1.0 17.749593651735438 -5.1058577398280045 5.020110612807559 1.0440469366770313 1.2415563509564609 0.4675888241003927 0.08011930073371952 0.18878635382640765 7.065577703158582 0.021253617278840436 0.06141695236933659 7.836863098345838e-06 5.1058577398280045 0.19750941427942958 VVYAFS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VVYAFSPK 8 0 A7KAX9;A7KAX9-2;G3V174 A7KAX9 ARHGAP32 Rho GTPase-activating protein 32 1 VVY(0.149)AFS(0.851)PK;VVYAFS(1)PK 72.325 0.032987999999999996 63730000.0 174501.0 167454.0 159833.0 211100.0 202250.0 175667.0 205098.0 190829.0 178117.0 146034.0 True False 204040.57274814736 184077.7264550675 163644.02489002838 199272.751395434 162620.5643637732 166454.71327592057 185669.63265906836 185819.9409500384 180721.62416074224 172508.8081954918 1.1827835046945714 1.0670627684498608 0.9486125757971872 1.1551453718792872 0.9426797742378874 0.9649055895585891 1.0762907390135255 1.0771620469342185 1.0476080963700327 1.0 17.396310501345184 -4.812139575169641 3.8096291859960036 1.0293045308234308 1.1932710609618429 0.3549331617821363 0.0631431528317543 0.2613635415645211 6.630531953253481 0.015824105773350673 0.11272979090622255 1.5412050551566934e-05 4.812139575169641 0.16396653013841211 VVYAFS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 VVYAFSPK 8 0 A7KAX9;A7KAX9-2;G3V174 A7KAX9 ARHGAP32 Rho GTPase-activating protein 32 1 VVY(0.002)AFS(0.998)PK;VVYAFS(1)PK 85.53299999999999 0.013153999999999999 58151000.0 520060.0 415030.0 371340.0 416280.0 423030.0 375770.0 373980.0 382610.0 352160.0 307240.0 True False 512643.8490326769 414069.0235343672 340809.8586138523 446894.6198693711 398148.2071089801 359699.1930626538 393342.85450180667 400387.45738647686 312496.0323907989 360346.02462843346 1.42264327617124 1.1490872529017895 0.9457849825463577 1.2401819066276123 1.1049052296872872 0.998204970995735 1.091569845698721 1.1111193964171844 0.867210988973794 1.0 18.45902340392184 -4.807128123543137 3.364827110291971 1.0572104247716734 1.4600431772582703 0.5728526782711927 0.09786753890366796 0.2098290565225642 3.8604579671327572 0.024354383129416797 0.21202466805239584 1.5590924787435522e-05 4.807128123543137 0.4028327524865969 VWDYETGDFER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VWDYETGDFER 11 0 P43034 P43034 PAFAH1B1 Platelet-activating factor acetylhydrolase IB subunit alpha 0 ; 112.11 0.0079654 5507900.0 16629.6 14645.5 16620.3 18204.9 20889.0 16748.7 16669.800000000003 14879.900000000001 17147.2 11617.9 False True 19444.662830428457 16099.40845126241 17016.59098483875 17184.938474082126 16795.95040294118 15870.368687598753 15090.71586509931 14489.318391557259 17397.945360684702 13724.133302754208 1.4168226438405573 1.1730728706949767 1.2399027763322439 1.2521693060671009 1.2238259445913797 1.1563840380662749 1.0995751449070268 1.055754711202746 1.2676899135913537 1.0 13.744427423548652 -1.5228787452887231 0.1242018681669217 0.9717360745620719 2.1150554511873527 0.5445767032157143 0.07655222424317269 71.79466426715857 0.6113013342126401 0.46961399074644133 14.264755112343384 0.029999999999420743 1.5228787452887231 1.1433193766252807 VWS(ph)PLVTEEGK ddPTM_PC-9_AZD4547_30min_R2 4 VWSPLVTEEGK 11 0 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 1 VWS(1)PLVTEEGK;VWS(1)PLVTEEGK;VWS(1)PLVTEEGK;VWS(0.998)PLVT(0.002)EEGK 116.24 0.0012805 39843200.0 90854.0 100208.0 96827.0 100131.0 84939.0 103106.0 97603.0 120331.0 99505.0 88849.0 True False 119743.68211940324 132598.27632575578 95543.01071436216 77047.34495852866 73146.68600386332 96658.76552069662 106289.47791793504 101736.60888129765 104764.63115651636 85738.42355353101 1.396616326222058 1.5465443710073312 1.1143546470120205 0.8986326289335602 0.8531377528558591 1.12736812171905 1.2396948009147022 1.18659294940008 1.221909930395516 1.0 16.387654270550712 -5.300088969014372 7.139653370858764 1.0788163052687014 1.4714535304908891 0.6017870063771344 0.12738561151190014 0.15398075800098798 24.056135138745137 0.037937201122237016 0.08119061867758853 5.010845715649562e-06 5.300088969014372 0.3926372252221877 VWS(ph)PLVTEEGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VWSPLVTEEGK 11 0 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 1 VWS(0.995)PLVT(0.005)EEGK;VWS(1)PLVTEEGK;VWS(1)PLVTEEGK;VWS(0.996)PLVT(0.004)EEGK 132.14 0.00012319999999999999 30188600.0 118312.0 152874.0 125833.0 124066.0 132089.0 100824.0 129575.0 90340.0 83713.0 84086.0 True False 138339.8848314846 168050.32041093102 128833.3359443099 117114.9842473989 106207.10865882061 95536.61194949185 117300.71795823854 87968.67072314209 84937.14425556354 99330.12617559034 1.3927283711180933 1.6918363731247144 1.2970217687689776 1.17904797624408 1.069233602613909 0.9618090264036057 1.1809178390741273 0.8856192386953773 0.8550995304829909 1.0 16.59994372361181 -5.777456941957393 1.2917365645355694 0.9827678429495927 1.5580837181145417 0.7824570270148175 0.11398133633589792 0.20886046388665075 0.6934534814780032 0.039601242216873084 0.09760859461106279 1.6693333047351964e-06 5.777456941957393 0.575315875164949 VWS(ph)PLVTEEGK ddPTM_PC-9_Lapatinib_30min_R1 3 VWSPLVTEEGK 11 0 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 1 VWS(1)PLVTEEGK;VWS(1)PLVTEEGK;VWS(0.996)PLVT(0.004)EEGK 119.39 0.00097011 29637000.0 49219.0 79534.0 81095.0 62179.0 72490.0 66163.0 83229.0 69269.0 66346.0 60013.0 True False 48517.128034340865 79349.84390955445 74427.68213575262 66751.8510830634 68226.28072082352 63333.36272348604 87538.19037737527 72487.49061891683 58873.414825647305 70386.16708770403 0.6892991910454017 1.1273499778824625 1.0574191665105546 0.948366047548631 0.9693137663798456 0.8997984311970005 1.2436845760943216 1.0298542116747806 0.8364344481535503 1.0 16.103004305075757 VWS(ph)PLVTEEGKR ddPTM_PC-9_AZD4547_30min_R2 3 VWSPLVTEEGKR 12 1 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 1 VWS(1)PLVTEEGKR;VWS(1)PLVTEEGKR;VWS(1)PLVTEEGKR 109.95 0.0005733 127230000.0 236036.0 278839.0 301647.0 287032.0 275447.0 364708.0 288640.0 310509.0 346610.0 277878.0 True False 311090.5381462065 368968.2537561616 297646.9636873514 220861.20700019374 237205.93861131073 341902.7511058731 314328.40083022875 262526.9688369811 364931.0969816605 268149.5757994803 1.1601380953846336 1.3759792558168078 1.110003485181453 0.8236492873117638 0.8846030723863276 1.2750449076285122 1.1722129333714872 0.9790318260033208 1.3609236408210934 1.0 18.032678445521725 -5.4358540643124895 7.312378464034416 1.066880362909694 1.2646163968736188 0.1833376885039455 0.16396798518784741 0.4512109776790298 33.064168420356395 0.044631779564484275 0.09331745065781744 3.6656072911427754e-06 5.4358540643124895 0.19773603396392492 VWS(ph)PLVTEEGKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 VWSPLVTEEGKR 12 1 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 1 VWS(1)PLVTEEGKR;VWS(0.998)PLVT(0.002)EEGKR;VWS(1)PLVTEEGKR;VWS(1)PLVTEEGKR;VWS(1)PLVTEEGKR 125.36 0.00043383 80111200.0 154882.0 165215.0 167039.0 154663.0 173927.0 132465.0 154016.0 120016.7 126118.0 99678.0 True False 181100.46354106063 181616.45333210373 171021.8432589348 145997.73353421118 139847.25289541605 125518.302208695 139426.48950072215 116866.3887932049 127962.2371581853 117748.8323493859 1.5380234345228743 1.542405556882373 1.4524292075481182 1.2399081215600063 1.1876742223690118 1.065983413204943 1.1841008247709328 0.9925057128926543 1.0867389052189838 1.0 16.845353227930048 -5.870143977586389 0.9371886145253412 1.059494742505651 1.5919405237048911 0.9307478533755471 0.05280664629219185 0.15147321048189027 0.2583838727094484 0.021656332497626576 0.057845865564620055 1.3485157476692127e-06 5.870143977586389 0.5324457811992402 VWS(ph)PLVTEEGKR ddPTM_PC-9_Lapatinib_30min_R1 3 VWSPLVTEEGKR 12 1 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 1 VWS(1)PLVTEEGKR;VWS(1)PLVTEEGKR;VWS(1)PLVTEEGKR 101.72 0.0012062999999999998 95860000.0 95349.0 165253.0 176317.0 144850.0 177097.0 168175.0 163388.0 166880.0 174822.0 146465.0 True False 93989.30577513481 164870.36683161388 161820.89686330233 155502.752205435 166680.50264609852 160982.54728507265 171847.43117637606 174633.85402539224 155131.7054027268 171781.280097655 0.5471452169974711 0.9597691130132902 0.9420170624605293 0.9052368926173685 0.9703065581496613 0.9371367310428503 1.0003850889845707 1.0166058485890639 0.9030768970550042 1.0 17.390213301473267 -4.761340843801947 24.997133699453162 0.9586028637528208 0.5471447655306951 0.9181811905348041 0.036917617249930076 0.5984190455602305 151061.88518775674 0.009248838381717384 0.051744604918497195 1.7324438043048397e-05 4.761340843801947 -0.41145809822212565 VWS(ph)PQMS(ph)LTKMGNFIAKFAMPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VWSPQMSLTKMGNFIAKFAMPK 22 2 A0A3B3ISZ2;A0A3B3IRI5 A0A3B3ISZ2 2 VWS(0.998)PQMS(0.985)LT(0.017)KMGNFIAKFAMPK 47.047 0.040809 0.0 7594.4 5499.7 6265.0 8085.7 8670.5 9837.2 5581.3 7697.7 7621.8 6763.8 True False 8879.981923762803 6045.67386974893 6414.381360144814 7632.684443193094 6971.577766705043 9321.319914599131 5052.598858887252 7495.643531387327 7733.254405971035 7990.023397788661 1.1113837196297134 0.7566528367641759 0.8027988205791831 0.9552768575503214 0.872535338086058 1.1666198520994222 0.6323634622003262 0.9381253543590173 0.967863799762002 1.0 12.963984012574318 -7.996012372538518 24.992822368637086 0.9736195379948216 0.8934737809664292 0.04682890520904903 0.149064124217662 373.3574118707653 2340055.4070899915 0.07998035214912452 0.03816047945772852 1.0092241340596571e-08 7.996012372538518 -0.08014575702839244 VWYVSNIDGTHIAK ddPTM_PC-9_Lapatinib_30min_R1 2 VWYVSNIDGTHIAK 14 0 P06744-2;P06744;A0A2U3TZU2;K7EQ48;A0A0J9YXP8;A0A2R8Y6C7;A0A0J9YYH3;A0A0J9YX90;K7EPY4;K7ENA0 P06744-2 GPI Glucose-6-phosphate isomerase 0 ; 139.77 9.0608e-05 11085800.0 89184.0 73679.0 105406.0 95255.0 120223.0 132935.0 93869.0 81696.0 109109.0 87740.0 False True 87912.21980565724 73508.40080232423 96739.92555892664 102260.37046136496 113151.7195075122 127249.67993662054 98729.07751545544 85491.89440591085 96819.99545129405 102905.74209379904 0.8542984873042834 0.7143274933610702 0.9400828718648933 0.993728516802825 1.0995666248086906 1.2365653980769304 0.9594127160121294 0.830778658862249 0.9408609615102157 1.0 16.65096396064459 -5.457390702827189 3.7764299582237424 1.011303899520568 0.7856663238950216 0.4154754739924654 0.10471766692086847 0.24289577239516458 6.72668893861902 0.032064697352341555 0.06971193621864198 3.4882636083871396e-06 5.457390702827189 -0.22563757562554654 VY(ph)CGAGVQKEHEEY(ph)MK ddPTM_PC-9_AZD4547_30min_R2 1 VYCGAGVQKEHEEYMK 16 1 A0A0G2JM70;F8W9F3;Q9NV79-2;Q9NV79 A0A0G2JM70 PCMTD2 Protein-L-isoaspartate O-methyltransferase domain-containing protein 2 2 VY(1)CGAGVQKEHEEY(1)MK 48.111999999999995 0.042885 0.0 5323.2 4904.2 9009.8 6696.9 5380.5 6188.9 7844.9 6969.1 5644.2 5520.5 True False 7015.866870561647 6489.386743141978 8890.324165101256 5153.033171073598 4633.510449190434 5801.907104640262 8543.080902414971 5892.185728986306 5942.540889137325 5327.228975309427 1.316982413010347 1.2181542736794126 1.6688458871030354 0.967300860345371 0.8697787293667625 1.0891041349134545 1.6036631693532104 1.1060507735438692 1.1155031849916228 1.0 12.379169576907858 -1.522878745393021 0.26636347155850826 1.113984856357908 2.830104518763731 0.09100602021100634 0.23893093246323274 157.54432645709088 2.1912196679160054 0.30574750406414086 123.72080965804432 0.0299999999922161 1.522878745393021 1.716119662405823 VY(ph)ENVGLMQQQK ddPTM_PC-9_AZD4547_30min_R2 3 VYENVGLMQQQK 12 0 Q06124;Q06124-1 Q06124 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 1 VY(1)ENVGLMQQQK;VY(1)ENVGLMQQQK;VY(1)ENVGLMQQQK 136.02 6.514800000000001e-05 50415800.0 68021.0 98922.0 123435.0 164584.0 135031.0 131502.0 110645.0 149613.0 128597.0 131832.0 True False 89650.26307530698 130896.60197485621 121798.1712490036 126641.70159745215 116284.27645472239 123279.159151772 120492.19065223339 126493.74861471765 135394.37488402115 127216.60180653763 0.7047056893693876 1.0289270434523545 0.9574078345075275 0.9954809340846901 0.9140652619503202 0.9690493017510919 0.9471420313165552 0.9943179334964533 1.0642822788956408 1.0 16.956927429501413 -4.755338957424218 24.99984254158599 0.9809212914133877 0.7047052367371711 0.8127896209261855 0.04039018564114903 85.5494036151903 350551.8727108974 0.010161157755153522 0.09106859387667758 1.7565521279807062e-05 4.755338957424218 -0.27621605467621657 VY(ph)ENVGLMQQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 VYENVGLMQQQK 12 0 Q06124;Q06124-1 Q06124 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 1 VY(1)ENVGLMQQQK;VY(1)ENVGLMQQQK;VY(1)ENVGLMQQQK;VY(1)ENVGLMQQQK 108.31 0.0015167 50046500.0 129444.0 124704.0 156173.0 156177.0 213654.0 169462.0 190834.0 153805.0 178399.0 144866.0 True False 151356.3125644621 137083.78897997556 159896.75660940033 147426.90902266567 171790.03242807178 160575.11439919876 172756.82200148553 149767.78171986784 181007.7478772504 171129.05904137527 0.884457107473883 0.8010550034452751 0.9343635587380913 0.8614954692587953 1.003862426348857 0.938327571592474 1.009511902707983 0.8751744593164464 1.0577265421268207 1.0 17.38472523587273 -5.971619831903378 1.2247310517600816 0.9757919245443245 0.849396747024095 0.4507101307376643 0.056949665842202915 0.4326188266217928 1.3172732195891153 0.019877448112720575 0.039435316613121774 1.0675301955989405e-06 5.971619831903378 -0.12639517752022955 VY(ph)ENVGLMQQQK ddPTM_PC-9_Lapatinib_30min_R1 6 VYENVGLMQQQK 12 0 Q06124;Q06124-1 Q06124 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 1 VY(1)ENVGLMQQQK;VY(1)ENVGLMQQQK;VY(1)ENVGLMQQQK;VY(1)ENVGLMQQQK;VY(1)ENVGLMQQQK;VY(1)ENVGLMQQQK 151.79 0.00027859 56628500.0 128467.0 135164.0 148259.0 96428.1 159292.0 153081.0 156513.0 119152.9 163857.0 102706.0 True False 126635.03702203745 134851.03606245155 136069.71731629028 103519.7441487118 149922.75774012157 146534.08247924031 164616.47731600955 124689.17872304747 145401.69916929552 120458.59525285754 1.0512743964531115 1.1194803972218212 1.1295974108834912 0.8593803035093595 1.2445999177179103 1.216468465132331 1.3665814130611362 1.0351206442455136 1.2070678631448366 1.0 16.878177814349876 VY(ph)ESIGQYGGETVK ddPTM_PC-9_Lapatinib_30min_R1 1 VYESIGQYGGETVK 14 0 Q8N3R9-2;Q8N3R9 Q8N3R9-2 MPP5 MAGUK p55 subfamily member 5 1 VY(0.999)ES(0.001)IGQYGGETVK 184.11 9.891900000000001e-06 5643600.0 18262.0 28804.0 21521.0 12275.0 24163.0 20760.0 19624.0 21988.0 18162.0 14590.0 True False 18001.580531159365 28737.30610771249 19751.626453462395 13177.744448199612 22741.77984628579 19872.143193923646 20640.034699030544 23009.642751140444 16116.40430566132 17111.862060047013 1.0519942521737409 1.6793792520574782 1.1542651748916757 0.7700941254644152 1.3290067303302764 1.1613080519344163 1.2061828588030261 1.3446603689532797 0.9418264505117827 1.0 14.062709137543246 -1.52288035527026 0.023060960677641348 1.0220985552352192e-06 2.7451512310238564 0.07665456721297914 0.22968060929900702 6718.20400741221 11.968590754665737 504.79416076325055 996.7339094109084 0.02999988878604228 1.52288035527026 2.7451502089253013 VY(ph)S(ph)LFLDESRSTQY(ph)MKEYQDAFLFNELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VYSLFLDESRSTQYMKEYQDAFLFNELK 28 2 Q9Y230;Q9Y230-2 Q9Y230 RUVBL2 RuvB-like 2 3 VY(0.912)S(0.668)LFLDES(0.398)RS(0.085)T(0.085)QY(0.308)MKEY(0.544)QDAFLFNELK 46.839 0.0071303 5544700.0 5803.3 7098.0 7465.2 6275.0 10412.0 9676.4 8561.9 8268.2 6964.4 4972.1 True False 6785.684069600321 7802.642530952215 7643.1986799286615 5923.432093824488 8371.843343167393 9168.952549671349 7750.8548492119735 8051.168510882049 7066.241174649654 5873.502370878058 1.1553045595495173 1.3284480090855502 1.3013017101729787 1.0085008432437161 1.4253579575751232 1.5610707156828196 1.3196308368993237 1.3707610898058498 1.2030711368544638 1.0 12.520005323992105 -8.586488219711157 4.198571128585704 1.0001075717378067 1.3112261368791311 0.3132021305364099 0.13983646982835013 0.39581458803257996 19.86162738240599 0.1426230828726578 0.037292548803696916 2.5912647087610308e-09 8.586488219711157 0.3111185651413244 VY(ph)SLFY(ph)T(ph)IIIPLLNPFIYSLRNK ddPTM_PC-9_Lapatinib_30min_R1 1 VYSLFYTIIIPLLNPFIYSLRNK 23 1 Q9NZP5 Q9NZP5 OR5AC2 Olfactory receptor 5AC2 3 VY(0.602)S(0.431)LFY(0.96)T(0.969)IIIPLLNPFIY(0.018)S(0.02)LRNK 49.618 0.037092 0.0 6302.8 11467.0 12884.0 8140.8 14209.0 16055.0 17746.0 18212.0 18248.0 15363.0 True False 6212.92091620804 11440.448866030372 11824.727253678233 8739.501588912703 13373.25455596882 15368.365076032955 18664.80104815514 19058.196006174716 16192.718080041177 18018.474080089254 0.344808383251134 0.6349288410982747 0.6562557517978048 0.48503006137295573 0.742196841781764 0.8529226730145413 1.0358702388000818 1.0577031063487432 0.8986731067274131 1.0 14.137189219208043 -6.694833894945219 1.6421274017178606 1.0026131219970151 0.5420425787295868 0.8334392153310203 0.09339914346863738 0.14514664218768628 0.8102384094815018 0.03913725588022715 0.037537114647513345 2.019138477975745e-07 6.694833894945219 -0.4605705432674283 VY(ph)TYIQSR ddPTM_PC-9_AZD4547_30min_R2 2 VYTYIQSR 8 0 Q92630;Q92630-2;A0A0A0MTH5;Q9NR20-5;Q9NR20-2;Q9NR20;Q9NR20-3;Q9NR20-4 Q92630;A0A0A0MTH5 DYRK2;DYRK4 Dual specificity tyrosine-phosphorylation-regulated kinase 2;Dual specificity tyrosine-phosphorylation-regulated kinase 4 1 VY(0.614)T(0.343)Y(0.043)IQSR;VY(0.928)T(0.045)Y(0.028)IQSR 87.696 0.024338 0.0 100087.0 87160.0 102845.0 162080.0 133799.0 110760.0 91387.0 111159.0 90364.0 107378.0 True False 131912.5840610727 115332.7654933026 101481.20810227076 124714.96011103757 115223.3183888544 103834.15969072921 99520.26595992246 93981.930729705 95140.45655823761 103618.72890331969 1.2730573464585953 1.1130494140775706 0.9793712891127692 1.2035947693143532 1.1119931657949813 1.0020790718983874 0.9604466973608482 0.906997525682773 0.918178186175275 1.0 16.660925265626105 -6.8933256627376 2.319189001219887 0.9387860531799044 1.132510275198702 0.6025336525954368 0.07371084741727833 0.22067841008084482 2.4170354615876812 0.030806449147555297 0.026146884648878908 1.278422299013171e-07 6.8933256627376 0.19372422201879758 VYALPEDLVEVKPK ddPTM_PC-9_Lapatinib_30min_R1 2 VYALPEDLVEVKPK 14 1 A0A0A0MSQ0;P13797-3;P13797-2;P13797 A0A0A0MSQ0 PLS3 Plastin-3 0 ; 191.48 1.7515999999999999e-06 5862600.0 53282.0 38964.0 42039.0 44873.0 44090.0 43757.0 46547.0 39100.0 40421.0 41322.0 False True 52522.188909277866 38873.781251941036 38582.71569523281 48173.1101119398 41496.71288427514 41885.61511254896 48956.97590377981 40916.72874156771 35868.361328000006 48464.45264189602 1.0837260310637256 0.8021091569769603 0.7961034034639904 0.9939885315097036 0.856229888551398 0.8642543726232068 1.0101625673052173 0.8442626814317193 0.7400962844464876 1.0 15.56463933715096 VYEDSGIPLPAES(ph)PK ddPTM_PC-9_AZD4547_30min_R2 5 VYEDSGIPLPAESPK 15 0 Q8IXM2-2;F8W038;F8W1H0;H0YIS7;Q8IXM2;Q8IXM2-3 Q8IXM2-2 BAP18;C17orf49;RNASEK-C17orf49 Chromatin complexes subunit BAP18 1 VYEDSGIPLPAES(1)PK;VYEDSGIPLPAES(1)PK;VYEDSGIPLPAES(1)PK;VYEDSGIPLPAES(1)PK;VYEDSGIPLPAES(1)PK 213.69 8.359e-21 105210000.0 414926.0 421587.0 261059.0 239310.0 282681.0 320611.0 436755.0 322626.0 353343.0 308531.0 True False 546863.8370030558 557856.7531668764 257597.18708707966 184140.77680264326 243435.62257924024 300563.1434868585 475625.348893453 272771.5649079408 372019.98961596854 297729.4235995281 1.8367812975671332 1.8737038026756876 0.8652056755853941 0.6184836371776563 0.8176404590319641 1.0095177690302521 1.5975087149371248 0.9161726832711107 1.2495237626106035 1.0 18.183642279766524 -5.256358218419933 24.909144940947524 1.0064814714362866 1.8552426674317453 0.6474748472590346 0.24968649646728347 257.2108190455603 1260901.8685948392 0.07012820089780598 0.1739383993873514 5.541684305376335e-06 5.256358218419933 0.8487611959954586 VYEDSGIPLPAES(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 10 VYEDSGIPLPAESPK 15 0 Q8IXM2-2;F8W038;F8W1H0;H0YIS7;Q8IXM2;Q8IXM2-3 Q8IXM2-2 BAP18;C17orf49;RNASEK-C17orf49 Chromatin complexes subunit BAP18 1 VYEDSGIPLPAES(1)PK;VYEDSGIPLPAES(1)PK;VYEDSGIPLPAES(1)PK;VYEDSGIPLPAES(1)PK;VYEDSGIPLPAES(1)PK;VYEDSGIPLPAES(1)PK;VYEDSGIPLPAES(1)PK;VYEDSGIPLPAES(1)PK;VYEDSGIPLPAES(1)PK;VYEDSGIPLPAES(1)PK 242.1 5.4361e-33 110801000.0 670140.3999999999 837237.0 496939.0 620887.4 587146.1 430235.2 665033.9 489322.7 431297.8 471399.8 True False 783581.9338437752 920352.3562534292 508787.9104116535 586101.09192211 472099.0365685457 407672.90872621705 602037.0745635132 476478.4976052559 437604.71438972617 556860.8521412374 1.407141354668319 1.652751046719296 0.9136715365342453 1.052509059791936 0.8477863630622153 0.732091162735962 1.081126590688795 0.8556509148975084 0.785842123228903 1.0 19.086957347774025 -5.268829128629499 24.90721481120199 0.9062570252418369 1.529946211227256 0.8133122022529027 0.1190743980798835 182.7874364422281 616088.3081014623 0.0308195469171106 0.06627017068129526 5.38481604206905e-06 5.268829128629499 0.623689185985419 VYEDSGIPLPAES(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 5 VYEDSGIPLPAESPK 15 0 Q8IXM2-2;F8W038;F8W1H0;H0YIS7;Q8IXM2;Q8IXM2-3 Q8IXM2-2 BAP18;C17orf49;RNASEK-C17orf49 Chromatin complexes subunit BAP18 1 VYEDS(0.001)GIPLPAES(0.999)PK;VYEDSGIPLPAES(1)PK;VYEDSGIPLPAES(1)PK;VYEDSGIPLPAES(1)PK;VYEDSGIPLPAES(1)PK 185.86 4.0444000000000004e-07 100539100.0 232113.4 359763.0 204026.4 280085.6 288400.7 255049.3 294886.0 274020.7 215654.3 257164.8 True False 228803.4203516154 358929.9908772725 187252.13695667987 300684.02936217154 271437.53784359206 244141.43598795694 310153.7541917208 286752.70208374754 191365.04179354582 301615.39302944305 0.7585933133368963 1.1900254402540873 0.6208308371661944 0.9969120817809832 0.899945905005899 0.8094462074225912 1.0283087712351746 0.950723035729663 0.6344670935772339 1.0 18.20235053328394 VYEDSGIPLPAES(ph)PKK ddPTM_PC-9_AZD4547_30min_R2 2 VYEDSGIPLPAESPKK 16 1 Q8IXM2-2;F8W038;F8W1H0;H0YIS7;Q8IXM2;Q8IXM2-3 Q8IXM2-2 BAP18;C17orf49;RNASEK-C17orf49 Chromatin complexes subunit BAP18 1 VYEDSGIPLPAES(1)PKK;VYEDSGIPLPAES(1)PKK 90.44200000000001 0.0016094000000000002 13527700.0 63466.0 63055.0 49679.0 43673.0 58225.0 65297.0 68954.0 59680.0 71472.0 58364.0 True False 83646.86782519275 83436.29564226937 49020.22400031802 33604.86459112382 50141.46378665796 61213.96826765584 75090.77241840199 50457.82730996867 75249.86400702003 56320.69412461898 1.4851888657499501 1.4814500591497073 0.8703767729114373 0.5966699294715264 0.8902849044387052 1.0868823479378587 1.3332714304310784 0.8959020852676685 1.3360961752445217 1.0 15.781377494135004 -5.252072941808434 24.320489137989387 0.9939807729933094 1.4833195909627186 0.4610155363020453 0.2084085336821475 427.98884327765165 1111288.1951912544 0.057511400713350806 0.14759216433043817 5.5966359545805976e-06 5.252072941808434 0.48933881796940915 VYEDSGIPLPAES(ph)PKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VYEDSGIPLPAESPKK 16 1 Q8IXM2-2;F8W038;F8W1H0;H0YIS7;Q8IXM2;Q8IXM2-3 Q8IXM2-2 BAP18;C17orf49;RNASEK-C17orf49 Chromatin complexes subunit BAP18 1 VYEDSGIPLPAES(1)PKK 51.684 0.03954 6692400.0 32724.0 43961.0 22613.0 35817.0 30267.0 24040.0 31526.0 27500.0 23408.0 27873.0 True False 38263.526871538765 48325.157551872406 23152.17968028007 33810.28961028076 24336.398623477482 22779.300079998677 28539.629051525546 26778.154138658505 23750.297716414774 32926.15425745338 1.1621013062245853 1.467683021041949 0.7031546866740197 1.0268520685991513 0.7391205918914303 0.6918299629493537 0.866776873739062 0.8132791315158473 0.7213201253541021 1.0 15.006946395955772 -5.264280411676388 24.999999018335817 0.8151735273123466 1.3148921798628477 0.6962332956713668 0.1306444250076616 114.34081369442232 1006165.7420100804 0.03215451081962816 0.07204066763118622 5.4415119633886126e-06 5.264280411676388 0.4997186525505011 VYEDSGIPLPAES(ph)PKKGPK ddPTM_PC-9_AZD4547_30min_R2 1 VYEDSGIPLPAESPKKGPK 19 2 Q8IXM2-2;F8W038;F8W1H0;H0YIS7;Q8IXM2;Q8IXM2-3 Q8IXM2-2 BAP18;C17orf49;RNASEK-C17orf49 Chromatin complexes subunit BAP18 1 VYEDSGIPLPAES(1)PKKGPK 99.603 0.0013815 9754300.0 26702.0 19756.0 22720.0 40370.0 38874.0 29405.0 21631.0 20594.0 19450.0 30228.0 True False 35192.68056389712 26141.74065036355 22418.717955015723 31063.32021028254 33477.016114084 27566.300701570035 23556.117095200472 17411.670503041132 20478.08729203801 29169.72692068714 1.2064796033088163 0.8961942194880081 0.7685611187232745 1.0649163872786367 1.1476629933872344 0.9450311542690529 0.8075535694677518 0.5969089306315307 0.7020321906927066 1.0 14.832184259717163 -7.288832387197823 3.296632548345226 0.7339300062440144 1.0015035173393756 0.35346200602665223 0.15033266167995296 0.26849179732753625 6.051141790078175 0.06825128861410247 0.046023748722064904 5.1424208128642525e-08 7.288832387197823 0.2675735110953612 VYEDSGIPLPAES(ph)PKKGPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VYEDSGIPLPAESPKKGPK 19 2 Q8IXM2-2;F8W038;F8W1H0;H0YIS7;Q8IXM2;Q8IXM2-3 Q8IXM2-2 BAP18;C17orf49;RNASEK-C17orf49 Chromatin complexes subunit BAP18 1 VYEDS(0.001)GIPLPAES(0.999)PKKGPK;VYEDSGIPLPAES(1)PKKGPK;VYEDSGIPLPAES(1)PKKGPK 87.208 0.0033441000000000005 30221600.0 138688.0 54270.399999999994 70060.90000000001 199569.0 163868.0 169947.0 168882.0 242182.0 174543.0 151875.0 True False 162165.13918713975 59658.0066514214 71731.41756344281 188387.7959414279 131759.24173628056 161034.68014540488 152884.27436020263 235824.97911303968 177095.3611720858 179408.73525816159 0.9038865301279281 0.3325256519175393 0.39982120970990814 1.0500480685644755 0.7344081744218562 0.8975855044832839 0.8521562461281978 1.3144565049951302 0.9871055660542563 1.0 17.45289060999403 -6.483244563022435 0.7622354123207349 1.0830612054010949 0.5472565429024785 0.405163241875689 0.21621797362226258 0.6511979087534234 0.8404102560216825 0.1371372110856165 0.18306752207847385 3.286664977194657e-07 6.483244563022435 -0.5358046624986164 VYEDSGIPLPAES(ph)PKKGPK ddPTM_PC-9_Lapatinib_30min_R1 2 VYEDSGIPLPAESPKKGPK 19 2 Q8IXM2-2;F8W038;F8W1H0;H0YIS7;Q8IXM2;Q8IXM2-3 Q8IXM2-2 BAP18;C17orf49;RNASEK-C17orf49 Chromatin complexes subunit BAP18 1 VYEDSGIPLPAES(1)PKKGPK;VYEDSGIPLPAES(1)PKKGPK 104.38 0.0007318 21569000.0 183668.0 82094.0 94425.0 108458.0 94549.0 83106.0 63044.0 63559.0 95551.0 69340.0 True False 181048.86063941385 81903.91638684014 86661.74099104044 116434.36312528173 88987.81371048608 79551.75010954814 66308.10984333891 66512.18317353718 84789.0401833634 81325.32661025757 2.2262297390709542 1.0071145091043456 1.0656181118872972 1.4317109808028223 1.0942201823172517 0.9781915846559204 0.8153439107734916 0.81785325612388 1.0425908350753423 1.0 16.311417090828186 -4.760773696019934 24.99770156896331 1.030027055787831 2.2262311142515707 0.8313400218586185 0.16189980274216875 7.074544233760397 265466.8502071415 0.04564497210187262 0.2647587043671384 1.7347076910026354e-05 4.760773696019934 1.1962040584637397 VYFQS(ph)PPGAAGEGPGGADDEGPVRR ddPTM_PC-9_AZD4547_30min_R2 3 VYFQSPPGAAGEGPGGADDEGPVRR 25 1 Q96C90 Q96C90 PPP1R14B Protein phosphatase 1 regulatory subunit 14B 1 VY(0.002)FQS(0.998)PPGAAGEGPGGADDEGPVRR;VYFQS(1)PPGAAGEGPGGADDEGPVRR;VY(0.01)FQS(0.99)PPGAAGEGPGGADDEGPVRR 63.095 0.00071637 98297400.0 55062.6 55868.5 82205.6 101479.5 99519.0 75436.3 57823.0 79204.0 59832.5 72549.0 True False 72571.36142677115 73926.90005693628 81115.50003181517 78084.96911764599 85702.50467298261 70719.25623580511 62969.1349820063 66964.84172685597 62995.12379953027 70009.08159219686 1.036599249358813 1.0559615749219613 1.1586425387539467 1.115354855995558 1.2241626760967954 1.0101440359944303 0.8994423801872123 0.9565165004866998 0.899813600847917 1.0 16.095254460438397 -6.9800087508802084 8.241923503019613 0.9379284810625613 1.117081183458092 0.7023004998254928 0.05527148553527537 0.1063306020809686 35.20567166322813 0.020255405282007397 0.0176182709022677 1.0471074489935763e-07 6.9800087508802084 0.17915270239553072 VYFQS(ph)PPGAAGEGPGGADDEGPVRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VYFQSPPGAAGEGPGGADDEGPVRR 25 1 Q96C90 Q96C90 PPP1R14B Protein phosphatase 1 regulatory subunit 14B 1 VY(0.039)FQS(0.961)PPGAAGEGPGGADDEGPVRR;VY(0.012)FQS(0.988)PPGAAGEGPGGADDEGPVRR;VY(0.001)FQS(0.999)PPGAAGEGPGGADDEGPVRR 63.657 0.00055961 59514000.0 106008.0 102221.0 101873.0 120052.0 114796.0 110057.7 117343.0 99329.0 96002.0 74554.0 True False 123953.06064656156 112368.82532494608 104302.03867550395 113325.87565383545 92302.54786998109 104286.080466492 106227.42155024919 96721.71899777467 97405.84763205948 88070.05003086057 1.4074371548912172 1.2759028215105022 1.184307703231184 1.2867697431093204 1.0480583108291346 1.1841265041855793 1.2061696514652382 1.0982362217789416 1.1060042272932462 1.0 16.42636386500498 -1.5228787452803376 0.2211992403673767 1.0457375618975089 2.7912981805436843 0.7012225457490895 0.06351301334717678 30.365172447205385 0.3893620423273806 0.09921110418966972 18.952262909096454 0.029999999999999995 1.5228787452803376 1.7455606186461754 VYFQS(ph)PPGAAGEGPGGADDEGPVRR ddPTM_PC-9_Lapatinib_30min_R1 4 VYFQSPPGAAGEGPGGADDEGPVRR 25 1 Q96C90 Q96C90 PPP1R14B Protein phosphatase 1 regulatory subunit 14B 1 VY(0.002)FQS(0.998)PPGAAGEGPGGADDEGPVRR;VY(0.039)FQS(0.961)PPGAAGEGPGGADDEGPVRR;VY(0.027)FQS(0.973)PPGAAGEGPGGADDEGPVRR;VY(0.018)FQS(0.982)PPGAAGEGPGGADDEGPVRR 68.234 0.00029264 86957600.0 103599.0 77548.0 109955.0 79002.0 84428.0 83133.0 68996.0 68506.0 94096.0 62724.0 True False 102121.65926227043 77368.44237053511 100914.924338574 84812.0706229465 79462.11103183453 79577.59538248826 72568.27527997916 71689.03885344851 83497.91760519256 73565.75982552362 1.388168347672518 1.0516909300472166 1.371764861505061 1.152874255959509 1.0801507551922975 1.0817205663507445 0.9864409128933053 0.9744892056232934 1.1350106055211704 1.0 16.166746819419043 -6.212244148820298 2.056640036594647 1.033068889153902 1.2504217271031197 0.5165913185469709 0.0977566167603928 0.26949892938591347 2.238650039632201 0.031366210391245486 0.04216238211496543 6.134170614388201e-07 6.212244148820298 0.21735283794921778 VYGPGVAK ddPTM_PC-9_Lapatinib_30min_R1 1 VYGPGVAK 8 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 95.95700000000001 0.028877 6878500.0 66660.0 75883.0 75311.0 63744.0 84304.0 71650.0 67352.0 59884.0 70126.0 76087.0 False True 65709.41617605329 75707.2975757376 69119.22028886693 68431.94640375051 79345.40446804103 68585.69652430783 70839.15700413307 62666.42925729008 62227.671420482584 89238.53657044515 0.7363345332784799 0.848370003423062 0.7745445291374093 0.7668429922058407 0.8891383422161516 0.7685659039261148 0.793818004267836 0.7022350619546638 0.697318376252841 1.0 16.445379234459686 -4.402398657140071 8.095957514082517 0.7942317253140917 0.18916986797611288 0.04185600139443846 0.08598370211196744 5594.7492399975245 17147.842218214813 0.020533348071431756 54463.30661033638 3.959144409132253e-05 4.402398657140071 -0.6050618573379788 VYIIS(ph)NLSWHSK ddPTM_PC-9_AZD4547_30min_R2 1 VYIISNLSWHSK 12 0 O14717-6 O14717-6 1 VY(0.001)IIS(0.949)NLS(0.05)WHSK 70.889 0.024768000000000002 4019600.0 28215.0 21238.0 32540.0 41641.0 25621.0 20249.0 21066.0 21844.0 16699.0 18041.0 True False 37186.78309154209 28102.768168273975 32108.498338741683 32041.310797036782 22063.966400652003 18982.826828977784 22940.833189750516 18468.51172518356 17581.675048315836 17409.390081253023 2.1360187185182316 1.6142304834984378 1.844320690666649 1.840461420388292 1.2673601026615615 1.0903786255797145 1.317727564416741 1.0608362291262021 1.0098960943639452 1.0 14.08757804019699 -6.3339600086790835 3.235996584715657 1.1167220408057894 1.8476056076871052 0.8624083507311318 0.14476871796016857 0.091754693638872 1.8836725623898778 0.04633544826867458 0.05468568437926423 4.6348959747828986e-07 6.3339600086790835 0.7308835668813158 VYLDLT(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 2 VYLDLTPVK 9 0 Q8N4X5-2;Q8N4X5;Q8N4X5-4;Q8N4X5-3 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 VYLDLT(1)PVK;VYLDLT(1)PVK 96.756 0.012232 11070700.0 64572.0 76436.0 74269.0 71905.0 81046.0 87120.0 80592.0 97894.0 83779.0 84532.0 True False 85104.55281896351 101142.44221255256 73284.14453349749 55328.413171175715 69794.16185579174 81672.37262781116 87764.5318726085 82766.73168032969 88207.38690178175 81572.56040953849 1.0432987807627037 1.2399076565056024 0.8983921083949227 0.6782723613602059 0.855608325954061 1.0012236004089066 1.075907528609902 1.0146393746229836 1.081336499172428 1.0 16.315796315832998 -6.9935703271883805 24.087756539153236 1.043387206996912 0.9409920713200808 0.10860162167469001 0.13533313872483468 279.95164111483524 1048783.9856327649 0.054834111503914366 0.04822248864048328 1.0149150036782443e-07 6.9935703271883805 -0.10239513567683112 VYLDLT(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 2 VYLDLTPVK 9 0 Q8N4X5-2;Q8N4X5;Q8N4X5-4;Q8N4X5-3 Q8N4X5-2 AFAP1L2 Actin filament-associated protein 1-like 2 1 VYLDLT(1)PVK;VYLDLT(1)PVK 92.943 0.016231 4283600.0 65161.0 85893.0 71223.0 65687.0 74721.0 71581.0 65747.0 59617.0 66474.0 53674.0 True False 64231.79219093607 85694.12003575038 65367.31986873065 70517.84110540833 70326.0576871382 68519.64749346084 69151.05795745824 62387.02346255861 58986.99811774751 62951.47938389055 1.0203380892645575 1.3612725367925147 1.038376230526813 1.1201935489931318 1.1171470214111414 1.088451743534326 1.098481856729076 0.9910334764670139 0.9370232232039083 1.0 15.941952661778473 -7.6424015768870435 1.3626768649181578 0.959736022053712 1.136366255024791 0.3565818134144745 0.08877829061458972 0.46673731601501567 1.6245286800064818 0.06653712638005886 0.02818838732179961 2.278234494155621e-08 7.6424015768870435 0.17663023297107905 VYNYNHLMPTR ddPTM_PC-9_Lapatinib_30min_R1 1 VYNYNHLMPTR 11 0 K7ELC7;P61353 K7ELC7 RPL27 60S ribosomal protein L27 0 80.834 0.010671 3762800.0 30498.0 27247.0 22113.0 25728.0 25271.0 29679.0 25042.0 25453.0 23600.0 23251.0 False True 30063.092927351758 27183.911245550684 20294.95449864846 27620.12294609202 23784.609464697613 28409.698355128137 26338.55222855294 26635.639300744842 20941.91948098266 27269.90436998995 1.1024275156767938 0.9968465923725828 0.7442253637303805 1.012842677090114 0.8721926245869845 1.0417967723565804 0.9658468864136559 0.976741206692932 0.7679498687215374 1.0 14.73502202057332 -4.995728763374893 11.550801510989263 0.9251812449492907 1.076278343682786 0.24941372417448093 0.09599594904378193 0.2789689080635582 647.969965187211 0.023179596440542016 0.0822388067000571 1.0098834072078996e-05 4.995728763374893 0.15109709873349542 VYQWDDPDPR ddPTM_PC-9_Lapatinib_30min_R1 1 VYQWDDPDPR 10 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 143.37 0.00059287 4745400.0 44307.0 40813.0 41261.0 37581.0 44123.0 53562.0 37217.0 39811.0 46816.0 36525.0 False True 43675.17405509133 40718.500006043265 37868.67985206597 40344.83210654093 41527.77188915565 51271.27811912032 39143.914155820414 41660.76439720082 41543.08908566459 42838.29758349673 1.019535707971668 0.9505162974013677 0.8839912412078373 0.9417935441506342 0.9694076149551295 1.196856107999781 0.9137597982161747 0.9725121386067979 0.9697651734337102 1.0 15.386613527316216 -6.5330402986837 24.998484839490587 1.0117341577657168 0.9458261577571895 0.13140267195674282 0.07523395414251836 438.31299307146827 1078288.6763783381 0.02560267486577739 0.02563017658610289 2.930621296917784e-07 6.5330402986837 -0.06590800000852737 VYS(ph)PYNHR ddPTM_PC-9_AZD4547_30min_R2 2 VYSPYNHR 8 0 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 VY(0.002)S(0.995)PY(0.002)NHR;VYS(0.999)PY(0.001)NHR 77.533 0.023407 27668000.0 135841.0 139121.0 157938.0 204985.0 204630.0 182973.0 169327.0 176496.0 149818.0 176799.0 True False 179035.61233167356 184089.1425905661 155843.638925144 157728.87523667983 176220.65667091165 171531.66938508378 184396.7749701358 149222.59867460193 157737.07362049093 170609.32082342773 1.049389397176996 1.079009878839441 0.9134532519851862 0.9245032714239656 1.0328899723672857 1.0054062026459307 1.0808130181877778 0.8746450542936045 0.9245513249756211 1.0 17.380336941365023 -7.771098577636648 24.999991783138626 0.9246986572512784 1.0081406788710865 0.258681576632652 0.06063150935520633 291.251291385875 753805.2790288418 0.03427158134536337 0.01679536010361085 1.6939532575423913e-08 7.771098577636648 0.08344202161980807 VYS(ph)PYNHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VYSPYNHR 8 0 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 VYS(1)PYNHR 83.883 0.008175 9680300.0 75139.0 96820.0 109220.0 92166.0 92992.0 77458.0 70956.0 77460.0 76608.0 52050.0 True False 87858.54863710277 106431.64973891126 111824.21901915639 87002.23782620378 74770.88514865763 73395.9661229841 64234.53400304658 75426.75707565424 77728.24707190284 61486.252972426715 1.4289136902927329 1.7309828554138784 1.818686513053634 1.4149868242128791 1.2160585746246135 1.1936971692826728 1.0446974876132447 1.2267255431792061 1.2641565116475675 1.0 15.90797626991294 -6.076890263271499 2.8152759430644716 1.1626020049527475 1.6651771835480638 0.7732866080611939 0.12170276996942002 0.12469418904780215 1.9362238483065817 0.03792365466747181 0.05362799173211702 8.3774093421962e-07 6.076890263271499 0.5025751785953163 VYS(ph)PYNHR ddPTM_PC-9_Lapatinib_30min_R1 1 VYSPYNHR 8 0 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 VYS(1)PYNHR 108.43 0.0021501999999999997 14209000.0 88731.0 84415.0 97390.0 98240.0 101300.0 78488.0 87467.0 97478.0 85316.0 88723.0 True False 87465.67966872735 84219.542253942 89382.9701362716 105464.89731903301 95341.73316346284 75131.2512044644 91995.6132806822 102007.1837409344 75706.81366269143 104058.65233403345 0.84054211453708 0.8093468478103394 0.8589672086983005 1.0135139649943328 0.9162307124390879 0.722008689515691 0.8840746177009068 0.9802854587573003 0.7275398245565279 1.0 16.667037402608848 -10.815611128917222 3.749928880103099 1.0002947636710733 0.8659398770619119 0.17350947875962175 0.09026530741004368 132640486.16309911 231660025.16855335 452946.35402886884 0.02284310705929992 1.528934466816587e-11 10.815611128917222 -0.1343548866091614 VYSLFLDESR ddPTM_PC-9_AZD4547_30min_R2 1 VYSLFLDESR 10 0 Q9Y230;Q9Y230-2 Q9Y230 RUVBL2 RuvB-like 2 0 125.71 0.0017060999999999999 3147000.0 11677.0 13883.0 11542.0 21118.0 17308.0 17382.0 16482.0 18388.0 14615.0 14371.0 False True 15390.043103311617 18370.40825313814 11388.94553859117 16249.571369847576 14905.082957826971 16295.100792201685 17948.866070135187 15546.557114204152 15387.519062886147 13867.875664191964 1.10976212045584 1.3246735619769145 0.8212465855890528 1.1717419281314552 1.0747920819850703 1.1750250136924016 1.2942765355533643 1.1210482045456094 1.1095801141784125 1.0 13.759459186427971 -6.766926101977472 24.94628080469126 1.157194649247924 1.101350605323308 0.013183884291394943 0.13470548986836564 548.2847414933763 2492856.5665388294 0.04644152700121416 0.04212202105420924 1.710306310042366e-07 6.766926101977472 -0.05584404392461595 VYSS(ph)SEFLAVQPTPTFAER ddPTM_PC-9_AZD4547_30min_R2 2 VYSSSEFLAVQPTPTFAER 19 0 V9GYV0;O60307 V9GYV0 MAST3 Microtubule-associated serine/threonine-protein kinase 3 1 VYS(0.004)S(0.994)S(0.002)EFLAVQPTPTFAER;VYS(0.011)S(0.942)S(0.047)EFLAVQPTPTFAER 260.97 4.2560999999999995e-66 9822000.0 17568.5 22528.4 30162.0 37652.0 37241.0 27832.3 34448.0 35966.0 29665.2 36949.0 True False 23154.917552498937 29810.264733126653 29762.03217249929 28971.913117601118 32070.72997645217 26091.941881187136 37513.805265381445 30408.281116459988 31233.24190929389 35655.42675640032 0.6494079487729738 0.8360652906159809 0.8347125495323616 0.8125526954294698 0.8994627997460534 0.7317803839356237 1.0521204954768222 0.8528373906224964 0.8759744238284114 1.0 15.121834051133561 -1.8828107673001695 0.17890785720407604 0.982217841655339 1.6269481971431896e-17 0.45123411296957827 0.08193104313484516 50.48704602158823 0.6342092858508482 0.1874641754875811 13.107183180224354 0.013097524897950054 1.8828107673001695 -0.982217841655339 VYSS(ph)SEFLAVQPTPTFAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VYSSSEFLAVQPTPTFAER 19 0 V9GYV0;O60307 V9GYV0 MAST3 Microtubule-associated serine/threonine-protein kinase 3 1 VYS(0.156)S(0.753)S(0.091)EFLAVQPTPTFAER;VYS(0.034)S(0.963)S(0.003)EFLAVQPTPTFAER 212.32 1.6847999999999998e-21 7642700.0 10577.7 13138.8 14345.3 14583.4 22664.1 15615.9 18632.3 17268.5 16088.2 12886.9 True False 12368.29569090195 14443.133232695825 14687.346356853202 13766.339378020717 18223.232300603147 14796.974713779182 16867.31365782972 16815.220172488152 16323.459489115856 15223.192957355723 0.8124639637393344 0.9487584682894675 0.9648006432025416 0.9043003932607275 1.1970703092085442 0.9720020468261492 1.1080010419022883 1.1045790603582395 1.0722756740220187 1.0 13.893983365238638 -5.137624905437541 0.6799668695138529 1.0784269928157106 0.7559788969719803 0.5250250109272745 0.07388377240359728 1.6602524064860515 0.7980445319793004 0.03390366816330961 0.38467210070016566 7.284086501243985e-06 5.137624905437541 -0.32244809584373035 VYSS(ph)SEFLAVQPTPTFAER ddPTM_PC-9_Lapatinib_30min_R1 2 VYSSSEFLAVQPTPTFAER 19 0 V9GYV0;O60307 V9GYV0 MAST3 Microtubule-associated serine/threonine-protein kinase 3 1 VYS(0.028)S(0.971)S(0.001)EFLAVQPTPTFAER;VYS(0.046)S(0.953)S(0.001)EFLAVQPTPTFAER 245.04 1.1811999999999998e-53 7569000.0 20419.4 16034.1 19134.4 17449.7 17327.9 18824.3 16190.1 16256.900000000001 18339.1 15364.2 True False 20128.215611540654 15996.97402658217 17561.243492919974 18733.009148492773 16308.706989962146 18019.228570586547 17028.3441592323 17012.254922731267 16273.55743871563 18019.88149849037 1.1170004427180562 0.8877402455683367 0.9745482229942067 1.0395744916559049 0.905039635878206 0.9999637662487472 0.9449753684927874 0.9440825082094176 0.9030890375210825 1.0 14.137301903347826 -4.745553280100066 24.987248084178187 0.9564132485639003 1.1170008930700535 0.5217617841836131 0.04639256942431344 734.5870105688165 1155368.8269785424 0.011227317449387689 0.2809716686461238 1.7965806586089164e-05 4.745553280100066 0.16058764450615315 VYSSS(ph)EFLAVQPTPTFAER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VYSSSEFLAVQPTPTFAER 19 0 V9GYV0;O60307 V9GYV0 MAST3 Microtubule-associated serine/threonine-protein kinase 3 1 VY(0.003)S(0.041)S(0.162)S(0.794)EFLAVQPTPTFAER 90.689 0.00098228 4383800.0 5565.5 7848.0 6349.4 8481.8 11772.0 12094.0 9793.4 7437.6 9110.0 5035.4 True False 6507.629226364408 8627.097574374891 6500.793776233593 8006.592244366617 9465.36110600908 11459.76934972979 8865.698253924076 7242.370880788602 9243.216515573245 5948.278159795531 1.0940357951565776 1.4503520754435337 1.0928866474625414 1.3460352776511446 1.5912774842954633 1.926569175460973 1.4904646379598412 1.217557532823508 1.553931451633892 1.0 12.538256398490622 -6.022604114475623 6.611500227082243 1.4967430447021803 1.2329356526404538 0.16352310323567432 0.24656581008109021 0.2953295479950914 52.04096375202526 0.07300019604871816 0.09904092684049515 9.492833978967927e-07 6.022604114475623 -0.26380739206172654 VYT(ph)HEVVTLWYR ddPTM_PC-9_AZD4547_30min_R2 3 VYTHEVVTLWYR 12 0 E5RIU6;A0A087WZZ9;P06493 E5RIU6 CDK1 Cyclin-dependent kinase 1 1 VYT(0.989)HEVVT(0.01)LWYR;VY(0.001)T(0.999)HEVVTLWYR;VY(0.009)T(0.991)HEVVTLWYR 79.885 0.031238 24832600.0 58661.0 58387.0 91293.0 102133.0 77399.0 72081.0 69845.0 72126.0 62612.0 72951.0 True False 77313.97777540144 77259.4559299845 90082.39517021351 78587.81478912028 66653.4848539895 67573.76367522094 76061.06969230619 60980.58399059651 65921.54249506848 70397.00769455628 1.0982565922525716 1.0974821013018554 1.2796338668408982 1.1163516371335396 0.9468226993850443 0.9598953973784647 1.0804588459544413 0.8662382960250748 0.9364253489451388 1.0 16.10322648631014 -6.182329134153595 4.577633305621249 0.9637667443289137 1.1581546124359094 0.6279784119038099 0.06932222385733161 0.14977751439304593 5.764616617514545 0.02149884922166231 0.027952164786140692 6.57159613999721e-07 6.182329134153595 0.1943878681069957 VYT(ph)HEVVTLWYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 VYTHEVVTLWYR 12 0 E5RIU6;A0A087WZZ9;P06493 E5RIU6 CDK1 Cyclin-dependent kinase 1 1 VYT(1)HEVVTLWYR;VYT(1)HEVVTLWYR;VY(0.001)T(0.999)HEVVTLWYR 132.14 0.00023426 31464000.0 65316.0 61139.0 60588.0 77890.0 65465.0 65906.0 73587.0 79013.0 67530.0 48956.0 True False 76372.70875019644 67208.4758664254 62032.64770126956 73526.0758227871 52637.6031944346 62449.773339117855 66616.30663625611 76938.99247119375 68517.49849579147 57831.335264517234 1.3206111946209096 1.1621463616397176 1.0726476817029342 1.2713881753980436 0.9101917317605275 1.0798604779480907 1.1519067704654737 1.3304031822761688 1.184781540706199 1.0 15.819563792361809 -4.777578403621654 4.028405556899749 1.1329023497309394 1.3377788810411078 0.19941384409388951 0.11619232256438539 0.40869383124538045 12.609965448018649 0.030181334264880268 0.24527432440102026 1.6688664978588568e-05 4.777578403621654 0.20487653131016836 VYT(ph)HEVVTLWYR ddPTM_PC-9_Lapatinib_30min_R1 1 VYTHEVVTLWYR 12 0 E5RIU6;A0A087WZZ9;P06493 E5RIU6 CDK1 Cyclin-dependent kinase 1 1 VYT(1)HEVVTLWYR 125.47 0.00061257 2423400.0 18415.0 19464.0 14878.0 15809.0 15893.0 17098.0 15784.0 13130.0 15122.0 13676.0 True False 18152.39872310259 19418.932303864596 13654.788270740833 16971.64659727802 14958.204986840205 16366.758397384716 16601.21828829486 13740.067733421598 13418.8011182805 16039.878377875466 1.1317042620560651 1.2106658072077412 0.8513024817928485 1.0580907284613694 0.9325634917202824 1.0203792081092167 1.0349965191253365 0.8566191968371717 0.8365899542473878 1.0 13.969375582171388 -5.251326740464683 24.99984246137428 0.9526526380567611 1.1711850582194316 0.5634250105269709 0.07823825280151174 516.1706411549986 1276039.148959973 0.02036435597401765 0.052528648088317066 5.606260316094301e-06 5.251326740464683 0.2185324201626705 VYT(ph)PVASR ddPTM_PC-9_Lapatinib_30min_R1 1 VYTPVASR 8 0 Q9NS91;F8WE49 Q9NS91 RAD18 E3 ubiquitin-protein ligase RAD18 1 VY(0.002)T(0.998)PVASR 83.647 0.036086 4238000.0 13676.0 15619.0 16142.0 12244.0 16400.0 5374.1 11327.0 13827.0 16681.0 12060.0 True False 13480.97773212876 15582.835165128503 14814.867069921935 13144.464604786648 15435.384243640568 5144.262270638972 11913.456636563344 14469.452897945184 14802.210121282693 14144.554931060116 0.953086031892442 1.1016843754418923 1.0473901188216164 0.9292950304093794 1.0912598041346577 0.36369205646355507 0.842264510592872 1.0229698260898703 1.0464952904794782 1.0 13.78795916152544 VYT(ph)YIQSR ddPTM_PC-9_Lapatinib_30min_R1 1 VYTYIQSR 8 0 Q92630;Q92630-2;A0A0A0MTH5;Q9NR20-5;Q9NR20-2;Q9NR20;Q9NR20-3;Q9NR20-4 Q92630;A0A0A0MTH5 DYRK2;DYRK4 Dual specificity tyrosine-phosphorylation-regulated kinase 2;Dual specificity tyrosine-phosphorylation-regulated kinase 4 1 VY(0.047)T(0.936)Y(0.017)IQSR 85.807 0.022706999999999998 0.0 65277.0 64629.0 60449.0 57062.0 62920.0 55041.0 56775.0 66701.0 63840.0 57544.0 True False 64346.13800966427 64479.3555212939 55479.11655988789 61258.529833251865 59219.16930547952 52687.02473683777 59714.53169779145 69800.17196397208 56649.66693499718 67490.4037274398 0.9534116623383428 0.9553855357228855 0.8220297034218444 0.9076628150076658 0.8774457705814935 0.780659498639458 0.8847855161594346 1.0342236541636392 0.8393736561982504 1.0 16.042394763504888 -10.666300852901923 4.52125637686056 1.0000140841430616 0.8949154685397221 0.1698253339387341 0.06964708160076674 102180482.36268838 0.6622425305856561 14982.199112138713 0.017310905041904526 2.1562501721880547e-11 10.666300852901923 -0.10509861560333944 VYTDVNTHRPR ddPTM_PC-9_Lapatinib_30min_R1 2 VYTDVNTHRPR 11 1 A0A2R8YCC9;A0A2R8Y3W6;E7EU96;A0A2R8YD58;A0A2R8YFU2;A0A2R8YF43;A0A2R8Y5A0;A0A2R8YDP2;A0A2R8Y4H0;A0A2R8Y4D6;A0A2R8Y7T1;V9GYA2;A0A2R8YEW1;A0A2R8YDY7;A0A2R8YCK2;A0A2R8YF47;V9GY80;A0A2R8YEL7;A0A2R8Y797;P68400;Q8NEV1 A0A2R8YCC9 CSNK2A1;CSNK2A3 Casein kinase II subunit alpha;Casein kinase II subunit alpha 3 0 ; 82.749 0.0061271 5141800.0 15973.6 18660.9 19335.7 17638.9 16680.5 22458.0 16873.1 14875.3 17800.3 17028.9 False True 15745.813534800523 18617.691832572284 17745.993383960442 18936.123547645468 15699.38578512477 21497.523692154984 17746.706557287638 15566.460742952497 15795.442768531177 19972.322675417057 0.7883816915386244 0.9321745965724797 0.8885292748551027 0.9481182462044339 0.7860570871132764 1.0763657307928047 0.8885649829366706 0.779401624735038 0.7908665919949813 1.0 14.285714499885243 -10.763343083340557 3.3791104086677097 1.000317171348388 0.8804291479026728 0.14449896109221005 0.09021595560028278 35126670.005500585 49366241.72614428 116543.42081588112 0.022500891064450707 1.7244750553900196e-11 10.763343083340557 -0.11988802344571525 VYTY(ph)IQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 VYTYIQSR 8 0 Q92630;Q92630-2;A0A0A0MTH5;Q9NR20-5;Q9NR20-2;Q9NR20;Q9NR20-3;Q9NR20-4 Q92630;A0A0A0MTH5 DYRK2;DYRK4 Dual specificity tyrosine-phosphorylation-regulated kinase 2;Dual specificity tyrosine-phosphorylation-regulated kinase 4 1 VY(0.031)T(0.216)Y(0.752)IQSR 101.6 0.0065768 3591500.0 35642.0 38163.0 40813.0 47676.0 58493.0 52712.0 52324.0 53667.0 57864.0 42580.0 True False 41675.486638411676 41951.57042951949 41786.13670416445 45004.86828767746 47031.716545513846 49947.68992582735 47367.49192704506 52258.29811488676 58710.151532067015 50299.416936905465 0.8285481060483968 0.8340369130350489 0.8307479340482237 0.8947393633634089 0.9350350244518628 0.9930073342297523 0.941710556733925 1.0389444112332054 1.16721336165212 1.0 15.618254056178454 -6.718007969461431 0.6597600953590365 1.0726869768291394 0.8159317891719938 0.772862459784609 0.04885405365751886 0.36120783303683124 0.3465047735046056 0.0377523932215589 0.04179413375216773 1.9142207980521104e-07 6.718007969461431 -0.25675518765714556 VYVGNLGNNGNK ddPTM_PC-9_Lapatinib_30min_R1 2 VYVGNLGNNGNK 12 0 A0A087X2D0;P84103-2;P84103 A0A087X2D0 SRSF3 Serine/arginine-rich splicing factor 3 0 ; 233.57 7.4477e-21 8614000.0 38588.0 37754.0 40906.0 36728.0 40091.0 37246.0 43468.0 39774.0 36956.0 39351.0 False True 38037.728043827476 37666.582932598845 37542.86658172633 39429.09964101634 37732.926201938666 35653.075404666655 45718.56034944251 41622.04524212568 32793.626116067586 46152.7679180884 0.8241700283574879 0.8161283630799614 0.813447779521201 0.8543171172527468 0.8175658341641999 0.7725013474369181 0.9905919495572504 0.9018320486432403 0.7105451654442367 1.0 15.494129552706598 -7.230989998286646 24.996344158649173 0.8925616980117688 0.817993208761777 0.225213350093164 0.07603965987523545 1193.5995937908049 979845.169683341 0.02871985353038169 0.022243949855131985 5.8750288244555524e-08 7.230989998286646 -0.07456848924999182 VYYS(ph)PPVAR ddPTM_PC-9_AZD4547_30min_R2 2 VYYSPPVAR 9 0 O94964-2;H0YDM2;O94964-3;O94964 O94964-2 SOGA1 Protein SOGA1;N-terminal form;C-terminal 80 kDa form 1 VYYS(1)PPVAR;VYYS(1)PPVAR 96.171 0.0051903999999999995 127587000.0 359450.0 311860.0 438360.0 617330.0 513680.0 506030.0 412200.0 603930.0 374850.0 388560.0 True False 473747.62297553744 412662.64624531165 432547.0599806637 475014.106153424 442364.3987622241 474387.86410526995 448885.0014627908 510606.4954307865 394663.8057285581 374956.6326684585 1.2634731104875032 1.100560999037436 1.1535922351935761 1.266850789577678 1.179774833196159 1.2651806176335327 1.1971651181850163 1.3617748052540022 1.0525585396899084 1.0 18.516364218172846 -8.45676765537241 7.57523879942364 1.000158416945549 1.2174033868543956 0.5725951695122176 0.06874924167888423 0.17392369977588334 17.0148007549225 0.0659223407663281 0.017046107027525806 3.4932715317372094e-09 8.45676765537241 0.21724496990884656 VYYS(ph)PPVAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VYYSPPVAR 9 0 O94964-2;H0YDM2;O94964-3;O94964 O94964-2 SOGA1 Protein SOGA1;N-terminal form;C-terminal 80 kDa form 1 VYYS(1)PPVAR;VYYS(1)PPVAR 95.48299999999999 0.005411600000000001 78237000.0 226273.0 247198.0 277830.0 290170.0 331230.0 292582.0 308380.0 253670.0 257360.0 233383.0 True False 264576.54980453744 271738.1837653323 284454.5208761427 273912.71564383217 266327.8592544495 277238.48485882586 279168.0139221415 247011.43128558208 261123.40312271434 275693.49044118886 0.9596764485847631 0.985653246039553 1.031778154866601 0.9935407441267222 0.9660288272612035 1.0056040293703148 1.01260284918368 0.8959639594329658 0.9471511376813497 1.0 18.072705677878183 -7.742136927362014 24.99953268865612 0.9411681307097283 0.9941253067684724 0.31126433463922043 0.03078892921790616 237.5577365122775 307673.2236414786 0.014278206541921088 0.008227325195216673 1.8107690908316737e-08 7.742136927362014 0.05295717605874417 VYYS(ph)PPVAR ddPTM_PC-9_Lapatinib_30min_R1 4 VYYSPPVAR 9 0 O94964-2;H0YDM2;O94964-3;O94964 O94964-2 SOGA1 Protein SOGA1;N-terminal form;C-terminal 80 kDa form 1 VYYS(1)PPVAR;VYYS(1)PPVAR;VYYS(1)PPVAR;VYYS(1)PPVAR 122.94 0.0015260999999999999 125061000.0 555431.0 502366.0 544785.0 463186.0 497344.0 490056.0 471292.0 393041.0 509800.0 455438.0 True False 547510.4520864283 501202.80239227513 499994.8802309145 497250.24358320126 468091.20373592514 469097.447256332 495693.19371053297 411303.1197267131 452380.9555680068 534159.8514670103 1.0249936429755102 0.938301149020799 0.9360397994303287 0.9309015685427481 0.8763129659602177 0.8781967532153685 0.9279866173939636 0.7700000638331673 0.8469018297155675 1.0 19.026912018612457 -4.290231802848879 0.546022360593731 0.8703214238990296 1.1990427555208196 0.33490193625835973 0.05720547346947143 7.14416240184688 1.0950866847201386 0.03064229972978993 1.674390683855817 5.1258771942985705e-05 4.290231802848879 0.32872133162179007 VYYTAGYNS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 2 VYYTAGYNSPVK 12 0 Q9Y5Z4-2;Q9Y5Z4 Q9Y5Z4-2 HEBP2 Heme-binding protein 2 1 VYY(0.05)T(0.057)AGY(0.008)NS(0.885)PVK;VYYTAGYNS(1)PVK 206.67 6.8301e-08 29547000.0 69394.0 58355.0 73739.0 100202.0 95410.0 92101.0 71163.0 79022.0 70917.0 73728.0 True False 91459.84851513266 77217.1125557787 72761.17267979334 77101.97700546762 82163.96839647964 86341.9099103998 77496.36913900208 66810.965644912 74665.52784007513 71146.80516105673 1.2855088616852548 1.085320871133714 1.0226906537135732 1.0837025897498844 1.154851130848154 1.2135739576070288 1.0892459466531448 0.9390578465704876 1.0494572127455755 1.0 16.11851135370408 -7.580188751370293 6.36587334786335 0.997351232015541 1.132731626056704 0.43764552662017453 0.07300105310491639 0.21345669584650664 17.641361721955995 0.03634678352892083 0.020827916051550373 2.6291250834822826e-08 7.580188751370293 0.13538039404116298 VYYTAGYNS(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 VYYTAGYNSPVK 12 0 Q9Y5Z4-2;Q9Y5Z4 Q9Y5Z4-2 HEBP2 Heme-binding protein 2 1 VY(0.001)Y(0.016)T(0.076)AGYNS(0.907)PVK;VYY(0.001)T(0.001)AGYNS(0.999)PVK 136.6 6.389899999999999e-05 18786100.0 54794.0 59308.0 55120.0 63345.0 69728.0 67097.0 69578.0 55529.0 50619.0 46365.0 True False 64069.54196916922 65195.70628708277 56434.26984376405 59795.98501726087 56065.2989466362 63578.315202482096 62987.06813890262 54071.42258783883 51359.20711326039 54770.60747486197 1.1697796486660328 1.1903411207736851 1.0303750943362395 1.09175318248397 1.0236384354942283 1.1608108460667081 1.1500158760848462 0.9872343046889877 0.9377147612765239 1.0 15.74111426130554 -1.5228787453990025 0.14224280627695562 0.9539446394724761 1.7232455051799291 0.4025058039994843 0.06575117731769049 85.42577188059471 0.8095204661701504 0.2969825275970922 13.399292589462481 0.029999999991802917 1.5228787453990025 0.769300865707453 VYYTAGYNS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 2 VYYTAGYNSPVK 12 0 Q9Y5Z4-2;Q9Y5Z4 Q9Y5Z4-2 HEBP2 Heme-binding protein 2 1 VYYT(0.03)AGYNS(0.97)PVK;VYY(0.001)T(0.002)AGYNS(0.997)PVK 186.29 0.00012699 21038000.0 120399.0 87767.0 88904.0 91402.0 95248.0 94020.0 79014.0 80854.0 85932.0 69968.0 True False 118682.08818152733 87563.78090388828 81594.65629936448 98124.00798813361 89645.69990477288 89998.98377132467 83104.95830152874 84610.77201203897 76253.43325592372 82061.87557350041 1.4462512263106548 1.067045815026004 0.9943065001759867 1.1957319681323495 1.0924159273508178 1.0967210186503138 1.012710929658122 1.0310606651471863 0.9292187477195274 1.0 16.324424507819202 -4.762085738738442 6.085654896036144 1.051610570041759 1.4600429742463505 0.752304417069461 0.0688016238957555 0.06705199187698321 9.914627398088209 0.017806383607654522 0.11426000552774485 1.7294748912951562e-05 4.762085738738442 0.4084324042045915 WADPQISESNFS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 WADPQISESNFSPK 14 0 D6RAW2;Q9BW91-2;Q9BW91 D6RAW2 NUDT9 ADP-ribose pyrophosphatase, mitochondrial 1 WADPQISESNFS(1)PK;WADPQISESNFS(1)PK 142.4 0.00014615 2641400.0 73479.0 64234.0 55247.0 79030.0 69460.0 69569.0 62186.0 72466.0 60695.0 69321.0 True False 96843.79354185451 84996.38433566772 54514.38868225146 60810.85450132838 59816.67796687437 65218.8394323254 67720.43352975535 61268.044803019264 63903.21378870169 66894.09288967031 1.447718167007374 1.2706112104076792 0.8149357637925231 0.9090616506546381 0.8941997025885551 0.9749566309224353 1.0123529687658361 0.915896189878377 0.9552893391363937 1.0 16.029591198263063 -5.089133320629418 4.020183822640519 0.9344230202466818 1.4176754604228692 0.9024704443788055 0.05702680337503891 0.06047618111679818 1.7295520403512918 0.015487458642612995 0.050080234541250844 8.14454222777959e-06 5.089133320629418 0.4832524401761874 WAEYHADIYDK ddPTM_PC-9_Lapatinib_30min_R1 1 WAEYHADIYDK 11 0 Q9NRX4-2;Q9NRX4 Q9NRX4-2 PHPT1 14 kDa phosphohistidine phosphatase 0 69.815 0.036114999999999994 0.0 29850.0 22171.0 36348.0 23826.0 28283.0 32190.0 22511.0 29720.0 31229.0 26586.0 False True 29424.33352618041 22119.66441168217 33359.60774733751 25578.24352120603 26619.44954651744 30813.308738555002 23676.509432831066 31100.899698194196 27711.661164051173 31181.354676381765 0.9436515453405812 0.7093875375606004 1.0698575508845887 0.8203057175248452 0.8536976607587955 0.98819660205124 0.7593162541704699 0.9974197728410912 0.8887253761633807 1.0 14.928395986945095 -14.522790183589219 0.16491539275068864 1.4301376729458797 0.8625412193705524 0.08939361410040947 0.10569452506471406 320.52690140471736 2.9761650695049724 44.74548836258407 0.38903568446183756 3.000611824869137e-15 14.522790183589219 -0.5675964535753273 WAHDKFS(ph)GEEGEIEDDESGTENR ddPTM_PC-9_AZD4547_30min_R2 4 WAHDKFSGEEGEIEDDESGTENR 23 1 Q9Y2W1 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 WAHDKFS(0.999)GEEGEIEDDES(0.001)GTENR;WAHDKFS(1)GEEGEIEDDESGTENR;WAHDKFS(1)GEEGEIEDDESGTENR;WAHDKFS(1)GEEGEIEDDESGTENR 76.156 0.00016921 28502100.0 68536.4 87975.0 87016.7 67988.0 76216.0 87541.0 83300.0 111567.0 100820.0 76645.0 True False 90329.54955432098 116411.19830510906 85862.8017022982 52314.41700412905 65634.72398392319 82067.0474312582 90713.53862651747 94326.8837046125 106149.13937189073 73961.68187892254 1.2213019939459075 1.5739393067842569 1.1609092643790624 0.7073178391179543 0.8874152441715587 1.1095887133232636 1.2264937238044185 1.2753480087030524 1.4351909891078467 1.0 16.17449041136014 -5.501935071369805 23.78076491118616 1.088120670935127 1.3900717395282163 0.25256107355691537 0.20747748971609903 595.7891245859096 676493.6636199858 0.06011622846402901 0.1227778119666903 3.148218949288313e-06 5.501935071369805 0.3019510685930893 WAHDKFS(ph)GEEGEIEDDESGTENR ddPTM_PC-9_Lapatinib_30min_R1 2 WAHDKFSGEEGEIEDDESGTENR 23 1 Q9Y2W1 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 WAHDKFS(1)GEEGEIEDDESGTENR;WAHDKFS(1)GEEGEIEDDESGTENR 81.884 5.1443e-05 18038400.0 73295.0 88551.0 64095.0 68338.0 78196.0 74369.0 82249.0 99551.0 67325.0 89445.0 True False 72249.79985934333 88345.96560005707 58825.356513854895 73363.80448888506 73596.66501925112 71188.41123260642 86507.45077255218 104176.50288879327 59742.14953632022 104905.44907202914 0.6887135081966609 0.8421484906794292 0.5607464343769675 0.6993326384648784 0.7015523566246679 0.6785959343611192 0.8246230442534525 0.9930513982859426 0.5694856660429589 1.0 16.67873009177068 -7.315260171194519 5.509066569096032 0.8482947889075169 0.6962038302273538 0.25482765418523523 0.12729869172271702 0.30963092189413527 21.177567131971823 0.051444963134562725 0.03464715157462994 4.838824030911007e-08 7.315260171194519 -0.1520909586801631 WALS(ph)EGVPMSGFLCLS(ph)LT(ph)WS(ph)SPR ddPTM_PC-9_AZD4547_30min_R2 1 WALSEGVPMSGFLCLSLTWSSPR 23 0 D6RIU6 D6RIU6 SPATA20 4 WALS(0.932)EGVPMS(0.073)GFLCLS(0.807)LT(0.952)WS(0.952)S(0.285)PR 40.369 0.045762 0.0 2178.8 1004.0 997.48 1124.3 2137.6 2085.6 2208.6 2444.3 2629.9 1053.6 True False 2871.613078144671 1328.5233657099109 984.2527634581465 865.1100052618439 1840.8311376618294 1955.187102302143 2405.16112137487 2066.5895994262123 2768.911144952739 1016.7137846908815 2.8244065551031623 1.3066837351023335 0.9680726063504643 0.8508884390948522 1.8105696660948782 1.9230457300198718 2.365622614338929 2.032616878558927 2.7233929416965563 1.0 9.989697887630918 -6.607331664385298 3.3421485130098354 2.098424045831838 1.4292204169120455 0.11142003153361535 0.6506192109644857 0.4335947862708074 9.678381124526833 0.22588981204242803 0.22804733883347714 2.4698372457925223e-07 6.607331664385298 -0.6692036289197925 WCFALVAQAGVQWCSHSSLQPLPPRFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WCFALVAQAGVQWCSHSSLQPLPPRFK 27 1 F8VSK7 F8VSK7 CERS5 0 24.896 0.045591 3404000.0 42634.0 52275.0 21004.0 31474.0 24662.0 18054.0 40483.0 25999.0 18525.0 23308.0 False True 49851.094140116846 57464.516526560576 21504.815018113586 29710.613820084756 19829.658137648312 17107.21645774943 36648.15716846121 25316.55379821753 18795.89307914319 27533.555893973527 1.810557791085318 2.0870721074984093 0.7810402368994592 1.0790692613222448 0.7201996797656119 0.6213224519065411 1.3310361113394245 0.9194799936378268 0.6826540368241061 1.0 14.74890332218612 -5.262222722322215 24.999871837272583 0.8955540109760827 1.9488150197832321 0.8033859275356923 0.20914732967996852 26.5116189752526 846132.6889335911 0.054595849246531554 0.12549297800009734 5.467355047352704e-06 5.262222722322215 1.0532610088071495 WCNEHLK ddPTM_PC-9_AZD4547_30min_R2 2 WCNEHLK 7 0 Q60FE5;P21333-2;P21333;A0A087WWY3;F8WE98;O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;O75369-5;O75369-4;Q14315-2;Q14315 Q60FE5;O75369-2;Q14315-2 FLNA;FLNB;FLNC Filamin-A;Filamin-B;Filamin-C 0 ; 98.62899999999999 0.010156 58083000.0 152400.0 138715.0 178488.0 250730.0 201589.0 181867.0 155322.0 206901.0 157538.0 169615.0 False True 200860.02988307644 183551.91103032895 176121.13249801265 192928.07223988438 173601.84702943062 170494.82773992344 169145.3571014158 174929.20456199435 165865.13705979878 163676.83047678825 1.2271744833888465 1.1214287965843723 1.0760297104054026 1.178713393202249 1.0606378833444596 1.041655237600059 1.0334105114859435 1.0687475072215664 1.0133696783878086 1.0 17.32049058780661 -1.522878745305621 0.229141889286316 1.0011094883616298 2.1218994844133636 0.7265954085587858 0.03625416663498297 28.374041107408807 0.3706815001077131 0.054597852639505125 11.9128073021139 0.029999999998253486 1.522878745305621 1.1207899960517338 WCNEHLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 WCNEHLK 7 0 Q60FE5;P21333-2;P21333;A0A087WWY3;F8WE98;O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;O75369-5;O75369-4;Q14315-2;Q14315 Q60FE5;O75369-2;Q14315-2 FLNA;FLNB;FLNC Filamin-A;Filamin-B;Filamin-C 0 ; 83.005 0.012853 15859000.0 140037.0 149406.0 142284.0 161301.0 175719.0 164574.0 160186.0 164113.0 159909.0 133955.0 False True 163742.4982431754 164238.04029014465 145676.59017507496 152263.82791489773 141288.12335939615 155943.44972403086 145012.0224337906 159805.20764209685 162247.36660689395 158239.98111280348 1.0347732418297584 1.0379048274346379 0.9206054572973404 0.9622336077400971 0.8928724736049926 0.9854870344863381 0.9164057112116113 1.00989147318071 1.025324734405989 1.0 17.27175463344939 -10.133558143461142 8.902584403148492 1.0000017397585081 0.9729969490744163 0.016706523240111237 0.04976742507160811 0.0 0.0 0.05042576486131421 0.012230044398574003 7.35261551872927e-11 10.133558143461142 -0.027004790684091895 WCNEHLK ddPTM_PC-9_Lapatinib_30min_R1 2 WCNEHLK 7 0 Q60FE5;P21333-2;P21333;A0A087WWY3;F8WE98;O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;O75369-5;O75369-4;Q14315-2;Q14315 Q60FE5;O75369-2;Q14315-2 FLNA;FLNB;FLNC Filamin-A;Filamin-B;Filamin-C 0 ; 98.62899999999999 0.010156 43650000.0 217569.0 201634.0 204263.0 169561.0 198036.0 179985.0 180814.0 168116.0 186515.0 157168.0 False True 214466.42616273143 201167.1288613558 187469.28461798222 182031.08157891475 186387.9118337563 172287.4611155275 190175.66419030336 175927.28309763176 165507.71660997818 184334.2793868043 1.1634646950972058 1.091316978754829 1.0170071743660847 0.9875053201414776 1.0111408060062594 0.934646890901947 1.0316890858441017 0.9543926592647947 0.8978672722216754 1.0 17.491964858496516 -3.350356909042063 0.5520571195264796 0.9622495204038995 2.080091641820144 0.7596021444234871 0.035567370611203526 8.050551737710151 0.5415250942715184 0.01785506958189479 8.189234179197886 0.0004463166523702648 3.350356909042063 1.1178421214162446 WCNVQSTQDEFEELTMS(ph)QK ddPTM_PC-9_AZD4547_30min_R2 1 WCNVQSTQDEFEELTMSQK 19 0 D6RCP9;D6RFG8;P27707 D6RCP9 DCK Deoxycytidine kinase 1 WCNVQSTQDEFEELT(0.245)MS(0.755)QK 81.643 0.0064551999999999995 0.0 8426.1 8375.8 8574.8 11793.0 11021.0 10109.0 8914.1 7793.5 7324.8 9330.2 True False 11105.424526232247 11083.113552303861 8461.09254932521 9074.30605003373 9490.924386307548 9476.88263193918 9707.437631100114 6589.193651813685 7711.9739741244275 9003.552537891856 1.2334491834744752 1.230971164510906 0.9397504500269558 1.0078583994311252 1.054131060641293 1.0525714813186564 1.0781785956427674 0.7318437499068027 0.8565478950301271 1.0 13.136278643608135 -1.5228787692060977 0.3245328012029675 0.9045729594980508 4.497492674276403 0.4863562389926629 0.1044490683266497 51.768184104896065 0.7381706561507613 0.10467710585748277 110.92481631867332 0.02999999834726709 1.5228787692060977 3.5929197147783523 WCS(ph)TCSHSNIFEILVI ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WCSTCSHSNIFEILVI 16 0 Q6IPW1-2 Q6IPW1-2 1 WCS(0.748)T(0.245)CS(0.005)HS(0.002)NIFEILVI 54.95 0.03828 3129700.0 19554.0 16343.0 22201.0 24798.0 21047.0 19186.0 22680.0 18585.0 17761.0 14365.0 True False 22864.10599089564 17965.42503287574 22730.35603776135 23408.64845620074 16922.991437153672 18179.852384977312 20531.586211019465 18097.16344243521 18020.72102448919 16969.260786722567 1.3473837357008172 1.0587040448416358 1.3395018394405545 1.3794736700915462 0.9972733432439734 1.071340267173097 1.2099281441348468 1.0664674006657473 1.0619626423909596 1.0 14.050636099258684 -6.266714489424443 24.993782203696302 1.0784325598344122 1.2695282689744867 0.524552707191287 0.09898835169399059 407.9875491963803 1933065.5820239394 0.031161301392281862 0.03635851483441092 5.4110993842043e-07 6.266714489424443 0.19109570914007445 WDAWNELK ddPTM_PC-9_Lapatinib_30min_R1 1 WDAWNELK 8 0 B8ZWD1;A0A0A0MTI5;P07108;P07108-3;P07108-2;P07108-4;P07108-5 B8ZWD1 DBI Acyl-CoA-binding protein 0 96.331 0.028348 5837200.0 34321.0 29580.0 39050.0 34063.0 40676.0 37233.0 39419.0 35392.0 45084.0 38555.0 False True 33831.57624629945 29511.509327389776 35839.45973735916 36568.106650836955 38283.517652092916 35640.631384362205 41459.922941351695 37036.441524848226 40006.16516443314 45219.18037869177 0.7481687187378037 0.652632557252104 0.792572077539191 0.8086857467250471 0.8466212198338056 0.7881750860118822 0.9168658651957451 0.8190427428070008 0.8847167248366334 1.0 15.464647222273276 -1.8777904617414805 0.09207581969012614 1.1132170337888487 2.4733651573039963e-18 0.7519067966728623 0.04494279855977468 67.20882497201397 0.47873903709588944 0.790970436056338 9.436012953632014 0.013249806572314636 1.8777904617414805 -1.1132170337888487 WDDPYYDIAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WDDPYYDIAR 10 0 Q07960;H0YE29;E9PNR6 Q07960 ARHGAP1 Rho GTPase-activating protein 1 0 102.61 0.014792 0.0 9755.9 13728.0 12444.0 9844.7 13671.0 11669.0 10973.0 11967.0 11024.0 8603.5 False True 11407.38118219181 15090.82511480867 12740.712154132803 9293.133375948033 10992.265688094647 11057.057097899527 9933.558002359632 11652.87893008459 11185.205144640995 10163.246444731476 1.122415090908799 1.4848429777703167 1.253606534429504 0.9143863062344119 1.0815703178970855 1.08794538812265 0.9774000912384732 1.1465705366345145 1.1005543558809687 1.0 13.311073695201781 -5.600856757075627 6.78644220624421 1.051632628058233 1.3195355474169532 0.5377791840967824 0.10343672401929536 0.1424311257308459 10.04339258577181 0.02679759454721373 0.04679522434277592 2.5069359769281844e-06 5.600856757075627 0.2679029193587201 WDDPYYDIAR ddPTM_PC-9_Lapatinib_30min_R1 1 WDDPYYDIAR 10 0 Q07960;H0YE29;E9PNR6 Q07960 ARHGAP1 Rho GTPase-activating protein 1 0 91.265 0.037697 2383400.0 17659.0 19383.0 19464.0 17922.0 20729.0 17691.0 17438.0 19964.0 18598.0 15868.0 False True 17407.179421736015 19338.119854387962 17863.74505321276 19240.043666039393 19509.760974782013 16934.397169735217 18340.854315210698 20891.600322165174 16503.297394377783 18610.762657219064 0.935328645168865 1.0390826109905151 0.9598609891617451 1.0338127469792988 1.0483052916272741 0.9099249440573791 0.98549719068586 1.122554766129446 0.8867609403409483 1.0 14.183849556883274 -4.736437301975076 23.593467461854942 1.0005423166981209 0.9353280464177268 0.0764369033021931 0.06542166965940087 3027.8637739226133 2856969.2330124225 0.01552020700591505 0.9382318769785958 1.834690017679379e-05 4.736437301975076 -0.06521427028039406 WDEQTSNTKGDDDEES(ph)DEEAVKK ddPTM_PC-9_Lapatinib_30min_R1 1 WDEQTSNTKGDDDEESDEEAVKK 23 2 O43395 O43395 PRPF3 U4/U6 small nuclear ribonucleoprotein Prp3 1 WDEQT(0.005)S(0.015)NT(0.05)KGDDDEES(0.93)DEEAVKK 40.81 0.032995 19214000.0 22122.0 41517.0 38147.0 31886.0 32289.0 43931.0 42032.0 42487.0 32821.0 33987.0 True False 21806.53622332205 41420.8699372969 35010.700911678345 34231.00280857783 30389.824502616466 42052.17353816278 44208.21129584451 44461.10112641913 29124.35335954797 39861.60766516918 0.5470561149086937 1.0391168937596613 0.8783062942609431 0.8587461673927584 0.7623833127325395 1.0549542780962071 1.109042356424409 1.11538655188935 0.7306366969487949 1.0 15.282712276474912 -6.7680025140561995 24.994178444747796 1.015905553853675 0.8351664244093205 0.2614646803378138 0.1529852488553978 225.56900258675645 859022.1092628761 0.05236627268528507 0.04725833662183433 1.7060725128136462e-07 6.7680025140561995 -0.18073912944435444 WDET(ph)PGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WDETPGR 7 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 WDET(1)PGR 92.838 0.035006999999999996 15700000.0 48236.0 37800.0 36937.0 48543.0 48476.0 42698.0 47385.0 43017.0 44370.0 39438.0 True False 56401.40209557341 41552.5341885029 37817.71816435255 45823.293088529404 38977.4757878777 40458.84171446689 42896.34976230849 41887.849330279016 45018.82731020689 46587.79720896375 1.2106475402258656 0.891918843085115 0.8117515836759976 0.9835900350255828 0.8366456051366649 0.8684429000365441 0.9207636405280608 0.8991163317380364 0.9663222991265409 1.0 15.507664497271332 -4.760333301977337 24.99968874196934 0.9017488513667824 1.2106479074011447 0.7032500191361866 0.058679939146647146 14.218778497437599 321230.11579092394 0.013888983317496936 0.08291310949646737 1.7364676544325714e-05 4.760333301977337 0.3088990560343623 WDET(ph)PGR ddPTM_PC-9_Lapatinib_30min_R1 2 WDETPGR 7 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 WDET(1)PGR;WDET(1)PGR 126.24 0.011151000000000001 129395000.0 328500.0 294970.0 304380.0 286930.0 295620.0 303510.0 238082.0 246397.0 334720.0 193439.0 True False 323815.5297604784 294287.0150879022 279355.0513407778 308031.78937042103 278232.21281128196 290529.58481636643 250408.72101582694 257845.50413647175 297020.3088421409 226874.67340873452 1.4272881361997445 1.2971347161246087 1.2313188032120945 1.3577178304758366 1.226369645544447 1.2805730161557172 1.103731488638636 1.13651074517225 1.3091823092436277 1.0 17.791536040754288 -1.5228787543989402 0.033444707786724585 0.18011251225800148 2.834472444911847 0.6101970741876077 0.07535689174871896 752.4732991135884 1.932718991988966 46.464724033340666 124.36205683886057 0.029999999370109255 1.5228787543989402 2.654359932653845 WDETPASQMGGST(ph)PVLTPGK ddPTM_PC-9_Lapatinib_30min_R1 1 WDETPASQMGGSTPVLTPGK 20 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 WDETPASQMGGS(0.034)T(0.918)PVLT(0.048)PGK 208.4 9.077299999999997e-73 0.0 14299.0 24002.0 25936.0 26259.0 22881.0 26543.0 23149.0 22845.0 28352.0 22947.0 True False 14095.093637884545 23946.42484367849 23803.642195855213 28190.174457456113 21535.184565776814 25407.81776475508 24347.541951073094 23906.462099772743 25158.699200204246 26913.35837504449 0.5237210994431031 0.8897598177818976 0.8844545472231823 1.047441722605513 0.8001671239121683 0.9440597271693366 0.904663833171019 0.8882749512948224 0.9348034106190457 1.0 14.716034808012422 -4.755044024921442 4.252576886907511 0.919609076975271 0.48263272691615017 0.7801532601737137 0.06353489940152729 0.102183485782782 3.7047977951897804 0.015045972130457125 0.140689164121127 1.7577454202913027e-05 4.755044024921442 -0.4369763500591208 WDGS(ph)EEDEDNSK ddPTM_PC-9_AZD4547_30min_R2 4 WDGSEEDEDNSK 12 0 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK 228.17 1.4151e-15 441556000.0 199166.0 188342.0 201480.0 245146.0 227991.0 229562.0 219635.0 209767.0 213744.0 215156.0 True False 262496.6450898485 249219.8682714504 198808.2435553065 188631.37716794465 196338.3850611241 215207.45185015516 239182.08951062636 177352.33011612287 225042.07147297534 207623.4539283893 1.2642918712853382 1.2003454501696518 0.9575423190092809 0.9085263422744372 0.9456464640494928 1.0365276551288933 1.1519993766846872 0.8542018098653386 1.083895230596606 1.0 17.663609899611096 -5.176008896805357 4.391869973655647 0.9897464346749477 1.2474561830068402 0.5841205061340694 0.08147237411870904 0.15224281149897032 5.226513595425878 0.021274426621406016 0.061817087417114364 6.667931093825197e-06 5.176008896805357 0.25770974833189253 WDGS(ph)EEDEDNSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 WDGSEEDEDNSK 12 0 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK 248.67 1.2685999999999998e-123 192194000.0 214336.4 214099.8 203952.90000000002 258063.0 263660.0 242585.0 258791.0 271067.2 212063.0 187751.5 True False 250619.3191831345 235354.21320771478 208815.91063168008 243604.56676153396 211997.71569914656 229863.4155535142 234276.4429954118 263951.97321943886 215164.0201912195 221789.3607099434 1.1299880137663365 1.0611609702753575 0.9415055346354957 1.0983600204345263 0.9558516018105919 1.0364041576102925 1.0563015387460313 1.1901020516698084 0.9701277802617929 1.0 17.758830635161182 -7.3451745324376745 5.0040487481894145 1.0709960605774906 1.0330856719868566 0.0 0.07636201771382672 0.8064496484972425 34.921899459198066 0.03198760789158081 0.021279624656724377 4.5167439089407465e-08 7.3451745324376745 -0.037910388590634 WDGS(ph)EEDEDNSK ddPTM_PC-9_Lapatinib_30min_R1 8 WDGSEEDEDNSK 12 0 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK 233.52 1.6235999999999999e-21 586262000.0 249582.0 220104.6 229416.0 203964.0 225066.0 206842.0 191928.0 209705.0 220552.0 183642.8 True False 246022.9149122661 219594.96132188625 210554.30205136954 218964.1929639577 211828.0603767809 197995.84983225225 201865.09272908344 219448.6598657404 195711.11124447823 215385.21329135052 1.1422460769369163 1.0195452044558009 0.9775708315062175 1.0166166452093715 0.9834846930287741 0.9192638937772587 0.9372281859294654 1.0188659495807322 0.9086562083523384 1.0 17.716559683262787 -1.5228787908516925 0.8015691182131203 0.9632766220384833 45.672882320627494 0.6847120435100821 0.035619327210364024 287.303719029712 0.9908125751585504 0.012637295150934431 23329.083793149726 0.029999996852042486 1.5228787908516925 44.70960569858901 WDGS(ph)EEDEDNSKK ddPTM_PC-9_AZD4547_30min_R2 7 WDGSEEDEDNSKK 13 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 WDGS(1)EEDEDNSKK;WDGS(1)EEDEDNSKK;WDGS(0.99)EEDEDNS(0.01)KK;WDGS(0.999)EEDEDNS(0.001)KK;WDGS(1)EEDEDNSKK;WDGS(1)EEDEDNSKK;WDGS(1)EEDEDNSKK 155.43 2.195e-12 197748500.0 258732.0 242356.0 239933.0 286749.0 280949.0 282372.0 268933.0 243257.0 257244.0 276487.0 True False 341003.3940400808 320692.8374701105 236751.33165056282 220643.4482778874 241944.08088274347 264715.2342017932 292867.51600774535 205667.22013976309 270841.39266596525 266807.2742860929 1.2780888188019515 1.2019643704550462 0.8873496132519175 0.8269768838509822 0.9068121606883587 0.9921589840835583 1.0976744048354112 0.7708456251429997 1.0151199714875339 1.0 18.02543847541736 -5.182068215751492 4.598406453423166 0.9316794291794622 1.2567280759761092 0.6385675451114208 0.09151628428407597 0.13344694310019442 5.115310561503729 0.02394680518526875 0.0684659824827144 6.575545454594607e-06 5.182068215751492 0.325048646796647 WDGS(ph)EEDEDNSKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 WDGSEEDEDNSKK 13 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 WDGS(0.999)EEDEDNS(0.001)KK;WDGS(0.998)EEDEDNS(0.002)KK;WDGS(1)EEDEDNSKK;WDGS(1)EEDEDNSKK;WDGS(1)EEDEDNSKK;WDGS(1)EEDEDNSKK;WDGS(1)EEDEDNSKK 191.19 1.0478000000000001e-08 95805000.0 215497.0 232598.0 171486.0 263388.0 253167.0 220839.0 259797.0 239954.0 215406.0 181626.9 True False 251976.38584023883 255688.7922533701 175574.87660427688 248631.22427541757 203560.74372451627 209257.81407515908 235187.14739260197 233655.46175227867 218555.90524188447 214554.41921225042 1.1744171327972894 1.1917199990200484 0.8183232824982618 1.1588259295160743 0.9487604332360149 0.9753134651966706 1.0961654775329535 1.0890265630983453 1.0186502149166898 1.0 17.710984091253422 WDGS(ph)EEDEDNSKK ddPTM_PC-9_Lapatinib_30min_R1 5 WDGSEEDEDNSKK 13 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 WDGS(0.999)EEDEDNS(0.001)KK;WDGS(1)EEDEDNSKK;WDGS(1)EEDEDNSKK;WDGS(1)EEDEDNSKK;WDGS(1)EEDEDNSKK 169.58 0.00013812 335030600.0 490817.0 433410.0 361039.0 408656.0 421059.0 416118.0 393153.0 374319.0 391714.0 334508.0 True False 483817.85957518464 432406.465773631 331355.7670708426 438709.9254764533 396293.1374538444 398321.60315843514 413508.5386275966 391711.2272586922 347595.0443887137 392327.2620961067 1.233199694026529 1.1021575800350736 0.8445902160876901 1.1182244209401497 1.0101085897945226 1.0152789307332408 1.0539887960329943 0.9984297934481453 0.8859823875904012 1.0 18.581698063546213 -4.970153517993265 4.869287373081534 0.9973646931226917 1.2140671876788522 0.5120509727738187 0.0740373191542119 0.148310116478444 8.888068860188973 0.018249548296139582 0.0752294122624427 1.0711406026986644e-05 4.970153517993265 0.21670249455616053 WDKDDFES(ph)EEEDVK ddPTM_PC-9_AZD4547_30min_R2 2 WDKDDFESEEEDVK 14 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;Q7Z6E9-4 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 WDKDDFES(1)EEEDVK;WDKDDFES(1)EEEDVK 92.671 0.0019133 12298500.0 72749.0 76159.0 43086.0 59753.0 55213.0 72189.0 78430.0 61988.0 71035.0 64545.0 True False 95881.66872679777 100775.90737958267 42514.6514881077 45977.86902464733 47547.62799575347 67675.01041814801 85410.11806095747 52409.17894253243 74789.7650791733 62285.29919596897 1.5393948486162705 1.6179725983576037 0.6825792287573887 0.7381817157205365 0.763384435967046 1.0865326375846944 1.3712725019146268 0.8414373795915601 1.2007611112834409 1.0 15.926604072818593 -5.247385308457789 24.925093496611087 0.9590448476406653 1.578683847469761 0.5889531272375719 0.20656825458269115 561.9573572065269 996635.1163699587 0.05687476661566217 0.14884656354368214 5.6573714120751186e-06 5.247385308457789 0.6196389998290958 WDKDDFES(ph)EEEDVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 WDKDDFESEEEDVK 14 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;Q7Z6E9-4 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 WDKDDFES(1)EEEDVK;WDKDDFES(1)EEEDVK 66.779 0.032775 2314700.0 29814.0 39914.0 26725.0 33434.0 33364.0 23346.0 35545.0 22735.7 24982.0 21261.0 True False 34860.921346658615 43876.39813756364 27362.2253551269 31560.8013744905 26826.563705477987 22121.69466171585 32177.920276485296 22138.911965465384 25347.314488699318 25115.450998016615 1.3880268902760937 1.746988263958652 1.0894578543418436 1.2566288925881872 1.0681298817845835 0.8808002159094342 1.2812001774933848 0.8814857422713098 1.0092319063153998 1.0 14.616287561258778 -5.277893943476059 22.86699872078139 1.063180214394846 1.5675074769846373 0.6499568223820651 0.1494236464242692 134.4514063083478 186848.36999757442 0.03831369104440463 0.08025582823769228 5.273586288762147e-06 5.277893943476059 0.5043272625897914 WDKDDFES(ph)EEEDVK ddPTM_PC-9_Lapatinib_30min_R1 3 WDKDDFESEEEDVK 14 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;Q7Z6E9-4 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 WDKDDFES(1)EEEDVK;WDKDDFES(1)EEEDVK;WDKDDFES(1)EEEDVK 95.40899999999999 0.0015122 20094600.0 89265.0 109152.0 77377.0 112677.0 103203.0 99314.0 108097.0 114134.0 86696.0 100473.0 True False 87992.0647308039 108899.26525027878 71015.3617438576 120963.642459453 97132.80244490462 95066.5717322415 113693.73373731693 119437.08230665184 76931.38353064709 117839.62417814277 0.7467103306251458 0.9241311316951546 0.6026441635328106 1.026510762429007 0.8242796353293284 0.8067453744465923 0.9648175181333035 1.0135562052208698 0.6528481745185041 1.0 16.846465208792914 -5.7734810334225894 24.999998161363695 0.8948196220733966 0.774458748096611 0.19142907444421242 0.13091173902114034 402.39669106641827 835426.2703210949 0.035527557385045296 0.053152580942864534 1.6846859990413315e-06 5.7734810334225894 -0.12036087397678563 WDNGPDGRR ddPTM_PC-9_AZD4547_30min_R2 3 WDNGPDGRR 9 1 Q14166;V9GY16 Q14166 TTLL12 Tubulin--tyrosine ligase-like protein 12 0 ;; 70.256 0.024148 9820700.0 35945.0 26770.5 68004.0 138857.0 82712.0 54742.0 33320.4 78959.0 35763.4 60566.0 False True 47374.762297553825 35423.540599339816 67102.2225269757 106845.66396926425 71228.866513045 51318.97408622165 36285.8510498321 66757.70084731602 37653.780311571856 58445.60277485566 0.810578727026754 0.6060941955855685 1.1481141324774613 1.8281215163586466 1.218720710049532 0.8780639030093123 0.6208482644898465 1.1422193916705805 0.6442534343707921 1.0 15.834806865494624 -6.814520028884727 7.6504767942723575 0.8496778850226865 1.134048236154412 0.13999811281987373 0.32799682900237087 0.5314403979427448 65.26803853642386 0.12851500818669054 0.1138612818708235 1.5327805156370292e-07 6.814520028884727 0.2843703511317255 WDNGPDGRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 WDNGPDGRR 9 1 Q14166;V9GY16 Q14166 TTLL12 Tubulin--tyrosine ligase-like protein 12 0 ;; 96.665 0.003184 6011400.0 33563.6 17696.3 45930.0 46373.0 53359.0 48949.0 39037.0 50975.0 49847.0 35281.0 False True 39245.25456868289 19453.071713227626 47025.14539049498 43774.871153294465 42903.6869907865 46382.028270210285 35339.13275659467 49636.96026247699 50575.918073740875 41677.16601575766 0.941648828853783 0.46675610587036176 1.1283191705672913 1.050332240362593 1.0294290877303198 1.1128882480318782 0.8479255221728211 1.190986936196905 1.2135162466329572 1.0 15.346969559420724 -5.28007701738252 24.93822451053645 1.0697055286804555 0.7042024444709089 0.5076739781719035 0.1447395459385029 518.930087762826 694357.6012019152 0.03621333660305812 0.07559074870496463 5.247143996311121e-06 5.28007701738252 -0.3655030842095467 WDNGPDGRR ddPTM_PC-9_Lapatinib_30min_R1 2 WDNGPDGRR 9 1 Q14166;V9GY16 Q14166 TTLL12 Tubulin--tyrosine ligase-like protein 12 0 ; 111.06 0.0014302 6201500.0 81672.0 41229.0 49190.0 42356.0 33492.0 40174.0 28663.2 27759.7 45289.0 26577.9 False True 80507.34230318955 41133.5367836022 45145.78807889105 45471.00153547394 31522.06640780546 38455.85167016805 30147.24024588527 29049.517003767196 40188.075905687445 31171.854602174324 2.582693372936942 1.3195729708277613 1.4482868810680902 1.4587198007879265 1.011234872294275 1.233672239299026 0.9671301445048578 0.9319149397591798 1.2892423764508454 1.0 14.927956371720416 -2.1704229660838434 0.9147120541867781 1.1156229581980464 199.99999999997016 0.8419414367393173 0.18267171364047605 96.23093173984705 0.7594650636804896 0.06093843511586221 39264.08237941663 0.006754248483029812 2.1704229660838434 198.8843770417721 up WDQTADQT(ph)PGATPK ddPTM_PC-9_AZD4547_30min_R2 3 WDQTADQTPGATPK 14 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 WDQT(0.02)ADQT(0.98)PGATPK;WDQT(0.004)ADQT(0.519)PGAT(0.478)PK;WDQT(0.003)ADQT(0.5)PGAT(0.497)PK 150.37 0.00030247 186356000.0 108627.0 105823.0 119743.0 152842.0 134614.0 150271.0 126381.0 135008.0 115191.0 131605.0 True False 143168.12641803775 140028.21526844616 118155.1295813136 117606.63828536036 115925.16970677844 140874.53061471306 137628.66416756183 114145.6157752055 121279.76109291252 126997.54900744413 1.1273298385439372 1.1026056515487415 0.9303733064516684 0.9260543939983179 0.9128142284067493 1.109269680523169 1.0837111837449283 0.8988017222955594 0.954977179014719 1.0 16.954441128371833 -5.179637696513453 6.077333790012014 0.9779639268908912 1.1189997699504037 0.4036336721267494 0.06717335299653379 0.2522686699389461 14.918634756133116 0.018870708742499187 0.05151542262521669 6.612448513145978e-06 5.179637696513453 0.14103584305951256 WDQTADQT(ph)PGATPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 WDQTADQTPGATPK 14 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 WDQT(0.003)ADQT(0.997)PGATPK;WDQT(0.004)ADQT(0.933)PGAT(0.063)PK 123.68 9.897299999999999e-05 69201000.0 98903.0 108600.0 87851.0 113080.0 103918.0 81967.0 96680.0 93458.0 80294.0 79970.0 True False 115645.32447670843 119381.09028760364 89945.70101677281 106744.49421030653 83556.01388160475 77668.50622534317 87521.77049741433 91004.82652693638 81468.14784867599 94467.92795782845 1.2241755162485812 1.2637208507515558 0.9521295000449845 1.1299548589438575 0.884490807492942 0.8221679876371933 0.9264707333952009 0.963340982429105 0.86238948614438 1.0 16.527536994283054 -5.386946682012727 0.9953175350610792 0.9096211834238682 1.3035695183601506 0.6758254726582635 0.0824208556581076 0.5053730039282824 0.7405891958589749 0.029529883321325463 0.1735509652809788 4.1025446650874915e-06 5.386946682012727 0.39394833493628234 WDQTADQT(ph)PGATPK ddPTM_PC-9_Lapatinib_30min_R1 2 WDQTADQTPGATPK 14 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 WDQTADQT(1)PGATPK;WDQT(0.001)ADQT(0.973)PGAT(0.026)PK 161.04 0.00019224 201475000.0 78804.0 76309.0 75321.0 80357.0 77822.0 75137.0 63882.0 64640.0 70550.0 52076.0 True False 77680.2405091164 76132.31119891109 69128.39812746791 86266.72184309388 73244.66296393883 71923.56566290173 67189.49738297341 67643.41037992177 62603.91607556473 61077.26721309177 1.2718355626177364 1.2464917746449584 1.1318187810578795 1.4124194774811865 1.199213165651246 1.1775832309583931 1.1000737336291873 1.1075055166420833 1.0249953695070648 1.0 15.89834789246482 -7.415103039597494 0.940116761771668 1.016957358052661 1.2579855807018416 0.6629431234957748 0.06770510443682769 0.3684678712814369 0.6126138910847729 0.05488365735936447 0.02810091819528678 3.8450054560693705e-08 7.415103039597494 0.24102822264918067 WDQTADQTPGAT(ph)PK ddPTM_PC-9_AZD4547_30min_R2 3 WDQTADQTPGATPK 14 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 WDQTADQT(0.044)PGAT(0.956)PK;WDQTADQT(0.002)PGAT(0.998)PK;WDQTADQTPGAT(1)PK 142.91 9.7111e-05 20407900.0 83020.0 79289.0 76647.0 110650.0 98084.0 101235.0 95472.0 84988.0 95436.0 101540.0 True False 109418.63307672623 104917.61866909682 75630.61069973985 85141.35202545853 84466.72965307962 94904.75944646967 103968.8230462289 71855.05742995348 100480.55212354449 97985.11550637078 1.1166862692488437 1.070750573971363 0.7718581573220935 0.8689212803951109 0.862036332932503 0.9685630205773362 1.061067515294903 0.7333262512231423 1.0254675070216297 1.0 16.580274991878753 -5.094168372206477 7.194509901453198 0.9062027986877325 1.1055872637678923 0.344787335761392 0.10116171306944961 0.24420743316829782 15.906298069829196 0.025220355463334548 0.06825521299261202 8.050662634760724e-06 5.094168372206477 0.19938446508015983 WDQTADQTPGAT(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 WDQTADQTPGATPK 14 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 WDQTADQTPGAT(1)PK;WDQTADQTPGAT(1)PK;WDQTADQTPGAT(1)PK;WDQTADQT(0.044)PGAT(0.956)PK 186.17 1.2939000000000001e-05 110724000.0 237603.0 277326.0 240648.0 310167.0 305811.0 268085.0 288484.0 283109.0 223491.0 211046.0 True False 277824.49502683786 304857.0924963156 246385.9609826223 292789.348564981 245889.5298326316 254026.15066332975 261156.70707670826 275677.6887287806 226759.1330715673 249306.96916078337 1.1143871988899874 1.2228181728032912 0.9882834876698643 1.1744130120011003 0.9862922430943044 1.018929200087876 1.0475307126624396 1.1057761026768176 0.9095579390936541 1.0 17.9275636871225 -4.839106306622856 0.37207610448445994 0.9983999660814136 1.2829114647845754 0.32362168317099194 0.07501745698017798 7.112055485432463 0.8099917315794045 0.06540175676956626 0.9108941164860538 1.4484172665048338e-05 4.839106306622856 0.28451149870316184 WDQTADQTPGAT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 4 WDQTADQTPGATPK 14 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 WDQTADQT(0.026)PGAT(0.974)PK;WDQTADQT(0.006)PGAT(0.994)PK;WDQTADQTPGAT(1)PK;WDQTADQT(0.004)PGAT(0.996)PK 175.7 0.00019224 34962200.0 187879.0 182771.0 147157.0 178541.0 179871.0 172848.0 144254.0 149332.0 155326.0 128107.0 True False 185199.81100721148 182347.80497891712 135058.31950244732 191671.50073531666 169291.3414199923 165455.69396836785 151722.76627975702 156270.50988326833 137831.55022470813 150250.12425815218 1.23261003557648 1.2136283139814004 0.8988899022166327 1.2756828101253106 1.1267301258874467 1.1012017113815509 1.0098012699082672 1.0400690891594353 0.9173473293632218 1.0 17.19700665849504 -7.284289753312497 1.4237055205679878 0.9767302503718852 1.1473936448083952 0.36774522205900895 0.0987468800643191 0.5042957894105262 1.9892362526274991 0.060695670711503294 0.03501728669696074 5.196491804499244e-08 7.284289753312497 0.17066339443651002 WDQTADQTPGAT(ph)PKK ddPTM_PC-9_AZD4547_30min_R2 1 WDQTADQTPGATPKK 15 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 WDQTADQT(0.001)PGAT(0.999)PKK 94.632 0.008913500000000001 0.0 15879.0 11445.0 14413.0 20254.0 23809.0 16561.0 17469.0 17689.0 20033.0 17698.0 True False 20928.19169628202 15144.372430826617 14221.874202713092 15584.75322118064 20503.53132325527 15525.438051987805 19023.707158062836 14955.5715027821 21091.903481819918 17078.398406851942 1.2254188711211658 0.8867560101391367 0.8327405101995514 0.9125418467183641 1.2005535199968838 0.9090687359629062 1.1139046358369544 0.8757010550112151 1.2350047691449648 1.0 14.059885066520026 WDS(ph)YENLSADGEVLHTQGPVDGSLYAK ddPTM_PC-9_AZD4547_30min_R2 5 WDSYENLSADGEVLHTQGPVDGSLYAK 27 0 Q68CZ2;E9PCX8;C9JHU5;Q68CZ2-3 Q68CZ2 TNS3 Tensin-3 1 WDS(0.491)Y(0.435)ENLS(0.074)ADGEVLHTQGPVDGSLYAK;WDS(0.85)Y(0.115)ENLS(0.035)ADGEVLHTQGPVDGSLYAK;WDS(0.742)Y(0.023)ENLS(0.234)ADGEVLHTQGPVDGSLYAK;WDS(0.928)YENLS(0.071)ADGEVLHTQGPVDGSLYAK;WDS(0.986)Y(0.011)ENLS(0.003)ADGEVLHTQGPVDGSLYAK 131.56 2.6738e-12 55921000.0 106434.29999999999 107356.0 146320.7 171869.6 154594.3 151402.3 147298.6 161661.5 138906.6 136165.59999999998 True False 140278.1934290315 142056.72753899705 144380.39191375312 132247.71907884994 133131.54993686132 141935.09024687376 160407.89004480155 136680.42978670375 146248.9192925555 131398.48378958282 1.0675784787111269 1.0811139020940452 1.0987980055002697 1.0064630524247682 1.0131893922768072 1.0801881890369749 1.2207742845927616 1.0401979219606465 1.11301831706638 1.0 17.00358910289865 -6.998754335732025 24.998768411710273 1.104509423962919 1.0540590471815816 0.0815699784123205 0.059581985590917076 87.40206987244315 1754002.5475959387 0.020982407851666884 0.018378824596518902 1.0028723653331295e-07 6.998754335732025 -0.05045037678133735 WDS(ph)YENLSADGEVLHTQGPVDGSLYAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WDSYENLSADGEVLHTQGPVDGSLYAK 27 0 Q68CZ2;E9PCX8;C9JHU5;Q68CZ2-3 Q68CZ2 TNS3 Tensin-3 1 WDS(0.669)Y(0.012)ENLS(0.319)ADGEVLHTQGPVDGSLYAK 88.544 3.0827e-07 19650000.0 42346.0 45068.0 45057.0 56215.0 61323.0 48913.0 56151.0 46348.0 45354.0 35829.0 True False 49514.34142837615 49542.05319596425 46131.32975962405 53065.45580148901 49307.19836083881 46347.91617358465 50831.970781964446 45131.414109765254 46017.21644866182 42324.51407779203 1.1698738309758097 1.1705285760612976 1.0899435177173005 1.2537759016903358 1.1649796680527194 1.0950607982975928 1.2010054194251538 1.0663185412315466 1.0872473660083288 1.0 15.369205884372459 -8.305461808173844 0.8674813627973867 1.0019614078980676 1.1658718037528624 0.5337309418411518 0.048489516675269115 0.4384955871694332 0.7138995765956477 0.04506744653879139 0.016543107852556686 4.9492363255600855e-09 8.305461808173844 0.16391039585479472 WDS(ph)YENLSADGEVLHTQGPVDGSLYAK ddPTM_PC-9_Lapatinib_30min_R1 2 WDSYENLSADGEVLHTQGPVDGSLYAK 27 0 Q68CZ2;E9PCX8;C9JHU5;Q68CZ2-3 Q68CZ2 TNS3 Tensin-3 1 WDS(0.866)Y(0.037)ENLS(0.097)ADGEVLHTQGPVDGSLYAK;WDS(0.991)Y(0.003)ENLS(0.005)ADGEVLHTQGPVDGSLYAK 122.12 1.2605e-12 7321600.0 49744.0 60199.0 65019.0 59555.0 61333.0 52404.0 56053.0 56824.0 57233.0 48558.0 True False 49034.6414380676 60059.6129141155 59673.38880059805 63934.87336965604 57725.513525317474 50162.80307969051 58955.15007056463 59464.25048621086 50786.816849791525 56951.18560053211 0.860994216731626 1.0545805549227119 1.0477988855080218 1.1226258539744725 1.0135963442485054 0.88080349075686 1.0351874056510213 1.0441266473942428 0.8917604842508671 1.0 15.797438255586506 -6.537239298522402 24.90706469047112 0.9738526677762324 1.031037529371832 0.08389515002884418 0.07932194380676359 558.3301430312977 968365.5814842292 0.02644089083552958 0.02645100528327148 2.902422963610023e-07 6.537239298522402 0.057184861595599545 WDSYENLS(ph)ADGEVLHTQGPVDGSLYAK ddPTM_PC-9_Lapatinib_30min_R1 2 WDSYENLSADGEVLHTQGPVDGSLYAK 27 0 Q68CZ2;E9PCX8;C9JHU5;Q68CZ2-3 Q68CZ2 TNS3 Tensin-3 1 WDS(0.009)YENLS(0.991)ADGEVLHTQGPVDGSLYAK;WDS(0.291)Y(0.008)ENLS(0.702)ADGEVLHTQGPVDGSLYAK 95.052 1.7677e-09 46526000.0 129738.0 138149.0 165383.0 141159.0 153087.0 161319.0 151049.0 151081.0 163887.0 124909.0 True False 127887.91232896487 137829.12447834905 151785.84813684152 151540.30375261974 144082.72364062222 154419.76242295626 158869.5781315668 158100.77480830683 145428.32025338174 146499.35421921962 0.8729588810172852 0.9408172835499564 1.0360854417809329 1.0344093635106195 0.9835041554177694 1.0540644581400997 1.0844387606913035 1.0791909333042315 0.9926891557198594 1.0 17.16053477958411 -5.027688181267129 2.0600049639653335 1.037981050795715 0.8615215994284419 0.7178803687626691 0.03281409733846293 0.23606992362430537 1.587469278112207 0.009464434093015141 0.06492081976800965 9.382354080077422e-06 5.027688181267129 -0.17645945136727315 WDVDDWDNENSSAR ddPTM_PC-9_AZD4547_30min_R2 1 WDVDDWDNENSSAR 14 0 A0A087WUZ3;Q01082;Q01082-2;F8W6C1 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 162.93 0.0025775999999999998 2078400.0 8250.8 9669.3 15076.0 12695.0 11255.0 12794.0 10388.0 14796.0 10760.0 12149.0 False True 10874.382772698755 12794.712131532706 14876.08238951659 9768.363885794812 9692.437525441559 11993.989157486389 11312.511875777484 12509.618178255634 11328.751633024633 11723.667207867795 0.9275581249355933 1.0913574997204056 1.268893267418338 0.8332174321051375 0.8267411001684635 1.023057797942028 0.964929460654224 1.0670396861709266 0.9663146720355442 1.0 13.517136300422985 -5.774796132730375 24.993310776621456 0.9552362156611806 1.0954784828388187 0.27823345434370717 0.10440635543889683 311.63377345835477 583132.0854893407 0.031070401614472307 0.04638255256463232 1.6795922702159878e-06 5.774796132730375 0.1402422671776381 WDVDDWDNENSSAR ddPTM_PC-9_Lapatinib_30min_R1 1 WDVDDWDNENSSAR 14 0 A0A087WUZ3;Q01082;Q01082-2;F8W6C1 A0A087WUZ3 SPTBN1 Spectrin beta chain, non-erythrocytic 1 0 117.95 0.00056535 1806600.0 8103.9 10773.0 11093.0 11305.0 10755.0 10802.0 12102.0 10904.0 11245.0 9423.1 False True 7988.336899926754 10748.055780391152 10180.976360218312 12136.407412374472 10122.412045143554 10340.023640691872 12728.58234445923 11410.639647009073 9978.469684900429 11051.870279508508 0.72280407730971 0.9725101280205338 0.9211994081305009 1.09813154746096 0.9159003670095295 0.9355903914166921 1.15171297007164 1.0324623216186102 0.9028761135028618 1.0 13.432002913387945 -4.239836312647835 1.470650444409001 1.0023576698367902 1.422528206425404e-10 0.5163599934227987 0.0781033812073114 4.099808909990323 2.6995237199354025 0.02222728476556574 8.92269346113935 5.756568638617785e-05 4.239836312647835 -1.0023576696945373 WDYLTQVEK ddPTM_PC-9_AZD4547_30min_R2 1 WDYLTQVEK 9 0 Q9HB71;Q9HB71-3 Q9HB71 CACYBP Calcyclin-binding protein 0 96.89 0.022851 2814200.0 13538.0 9136.3 13250.0 21885.0 21892.0 17878.0 13702.0 21930.0 17640.0 17404.0 False True 17842.802392106925 12089.4303049158 13074.296342603793 16839.751369879436 18852.673683426623 16760.08583379252 14921.451455708797 18541.222401266976 18572.414387226254 16794.69125736531 1.0624072880340665 0.719836412569596 0.778477921519996 1.0026829973724205 1.1225376754192362 0.9979395022485088 0.8884623853484056 1.103993048585262 1.105850301301688 1.0 14.035717653802294 -5.856528983837485 6.028853081376157 1.0345598114326047 0.841129780662724 0.3788894340335711 0.10461357551292365 0.2057599100121273 10.753110535035908 0.029968893329658262 0.04509563070571427 1.3914609287713053e-06 5.856528983837485 -0.19343003076988063 WDYLTQVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WDYLTQVEK 9 0 Q9HB71;Q9HB71-3 Q9HB71 CACYBP Calcyclin-binding protein 0 90.15 0.026281 0.0 10846.0 11859.0 16484.0 16612.0 18441.0 16091.0 14624.0 15324.0 16683.0 9999.3 False True 12682.0135817354 13036.28314659937 16877.041075918132 15681.283496830652 14827.61842982616 15247.15963341342 13238.708851408672 14921.7612371201 16926.957313864816 11812.093935584751 1.0736465228683931 1.1036386281459092 1.4287933340146304 1.327561699250435 1.2552912727147327 1.2908092093206518 1.1207757848526876 1.2632613081553017 1.433019192547325 1.0 13.527977114200617 -10.583753199168234 4.574467682330514 0.9999870858322835 1.2553094733020118 0.29169922735722154 0.1193004726960504 64225858.16377571 4.5162082954148906 8736.437544547958 0.03101564809519325 2.6076349956178264e-11 10.583753199168234 0.25532238746972835 WDYLTQVEK ddPTM_PC-9_Lapatinib_30min_R1 2 WDYLTQVEK 9 0 Q9HB71;Q9HB71-3 Q9HB71 CACYBP Calcyclin-binding protein 0 ; 134.59 0.0050978 10985700.0 66389.0 58138.0 65635.0 57933.0 61152.0 53848.0 55245.0 51032.0 60344.0 50541.0 False True 65442.28068574845 58003.38503298808 60238.743658426756 62193.58607882269 57555.15958945777 51545.04656581888 58105.31578413895 53403.133021475296 53547.42326950919 59276.944508350636 1.1040090076931894 0.9785150957775305 1.016225518336908 1.049203642236674 0.9709535480755033 0.8695631496079808 0.9802346640177002 0.9009090037350379 0.9033431752199323 1.0 15.855183463895976 -6.4755412531167735 4.825880074017022 0.9267580677564103 1.030140123244841 0.5352738612400898 0.046345424593278575 0.16129649366542562 8.426596069600944 0.014220844127431563 0.01572270259141767 3.3454823800436794e-07 6.4755412531167735 0.10338205548843071 WEAERDDWLHNR ddPTM_PC-9_AZD4547_30min_R2 2 WEAERDDWLHNR 12 1 Q03701 Q03701 CEBPZ CCAAT/enhancer-binding protein zeta 0 ; 126.66 0.00011584 7626900.0 26484.0 20172.0 34909.0 59585.0 41173.0 32658.0 28399.0 33124.0 24389.0 31540.0 False True 34905.3610985788 26692.20451504016 34446.08385086461 45848.598829073155 35456.839647712615 30615.89009732612 30926.455983847198 28005.446913796946 25678.152748869674 30435.794200028842 1.1468523170177605 0.8770004271817183 1.1317622804412302 1.5064038916727103 1.1649717242364261 1.005917239948255 1.0161212084887172 0.9201483861318266 0.8436826908510684 1.0 14.893481391939638 -6.933707586581802 2.7717033810216223 0.9409732995748443 1.1657604891966284 0.3346319165021342 0.14846270895469488 0.370204175759273 5.769742527213592 0.06536058760195144 0.054862961430115015 1.1649101072890842e-07 6.933707586581802 0.22478718962178412 WEETRTPESQPDT(ph)PPGTPLVSQDEKR ddPTM_PC-9_Lapatinib_30min_R1 1 WEETRTPESQPDTPPGTPLVSQDEKR 26 2 A0A0D9SEV0;M0R000;M0QYI1;A0A0D9SFD6;M0R3C8;A0A0D9SFL2;M0QYH2;Q96T60-2;Q96T60 A0A0D9SEV0 PNKP Bifunctional polynucleotide phosphatase/kinase;Polynucleotide 3-phosphatase;Polynucleotide 5-hydroxyl-kinase 1 WEET(0.001)RT(0.001)PES(0.007)QPDT(0.903)PPGT(0.073)PLVS(0.014)QDEKR 43.162 0.027836 6566900.0 66896.0 18871.0 26561.0 23693.0 19819.0 16750.0 10999.0 11422.0 23256.0 13176.0 True False 65942.05077277595 18827.305358930782 24377.257108424983 25435.46225753104 18653.28538565319 16033.64154615708 11568.47440147967 11952.707818061037 20636.66438346324 15453.454044083584 4.2671399277252275 1.2183234444042554 1.577463332073512 1.6459402658442632 1.2070625332331237 1.0375441956483265 0.7486012103493915 0.7734651285055058 1.335407885162351 1.0 13.915641714464348 -4.761193545606607 7.443566927179316 1.172415261920366 4.319275542289836 0.9148635762813635 0.28333394831063075 0.030637276463745384 11.798554787546939 0.081037739393463 0.48510427411053014 1.7330314910857975e-05 4.761193545606607 3.14686028036947 WES(ph)QQDVSQTTVSR ddPTM_PC-9_AZD4547_30min_R2 2 WESQQDVSQTTVSR 14 0 Q9NQT8;H0YBA8 Q9NQT8 KIF13B Kinesin-like protein KIF13B 1 WES(1)QQDVSQTTVSR;WES(0.993)QQDVS(0.007)QTTVSR 260.07 3.4532e-45 27887000.0 56053.0 59581.0 72160.0 90548.0 81801.0 85301.0 73752.0 89309.0 73587.0 79542.0 True False 73876.68802517146 78839.39308004205 71203.11125149361 69673.55755265447 70444.34313804048 79967.11498536398 80315.78512344428 75508.34616665536 77476.6585891621 76757.25879070065 0.962471682666732 1.027126220010265 0.9276401004059834 0.9077129466365936 0.9177548058370083 1.0418182754990752 1.0463607792775262 0.983729061671538 1.0093724008620877 1.0 16.228015569461085 -6.765060773796294 24.999999667217434 1.017120714589148 0.9494775840976748 0.48102763164828444 0.035155041496118075 94.85532749408969 654821.1387537486 0.013547546861804769 0.01241761289886302 1.7176680053104923e-07 6.765060773796294 -0.0676431304914733 WES(ph)QQDVSQTTVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 WESQQDVSQTTVSR 14 0 Q9NQT8;H0YBA8 Q9NQT8 KIF13B Kinesin-like protein KIF13B 1 WES(0.996)QQDVS(0.004)QTTVSR;WES(1)QQDVSQTTVSR;WES(1)QQDVSQTTVSR 244.54 5.9838e-37 21044700.0 77548.6 79574.5 80459.0 84284.5 93023.0 89787.4 93014.1 69884.1 80272.1 72022.6 True False 90676.04632533356 87474.13047045049 82377.44770245669 79562.3127190359 74795.81092119277 85078.79068231587 84203.13108423213 68049.71642332437 81445.92760260662 85079.72724941207 1.0657773509253952 1.0281430523868418 0.9682382673955497 0.9351500679568258 0.8791261248631898 0.9999889918888262 0.9896967680372294 0.799834680050583 0.9572894770083956 1.0 16.3765277878298 -5.245146538617419 1.773973271065277 0.9312275187614557 1.0677869275379592 0.36210556065471 0.058005256524452424 0.47042695202081874 2.5345033655112856 0.016963412978856136 0.07846321621278646 5.686610222111739e-06 5.245146538617419 0.13655940877650352 WES(ph)QQDVSQTTVSR ddPTM_PC-9_Lapatinib_30min_R1 2 WESQQDVSQTTVSR 14 0 Q9NQT8;H0YBA8 Q9NQT8 KIF13B Kinesin-like protein KIF13B 1 WES(1)QQDVSQTTVSR;WES(1)QQDVSQTTVSR 228.76 1.1119e-20 38404000.0 63882.0 60071.0 61778.0 54964.0 55408.0 61321.0 57069.0 54564.0 64236.0 40594.0 True False 62971.03096547598 59931.909290251264 56698.85130997626 59006.235914528996 52149.010376319275 58698.44377623279 60023.753579238444 57099.24263567526 57001.06524493231 47610.618811895045 1.322625761582063 1.258792907671216 1.1908866703452845 1.2393503253477325 1.0953230955126834 1.2328855461455914 1.2607219791951558 1.199296376744626 1.19723428653885 1.0 15.538995759778514 -14.516101330530223 0.2044177126102062 7.235478176393273e-13 1.252141984383489 0.6181211762376992 0.05382258344138808 104.0298973381296 1.0328887427674314 42.664554248426825 0.12930182183523048 3.047183931116165e-15 14.516101330530223 1.2521419843827652 WET(ph)MDVRKLDFPSASFDVVLEK ddPTM_PC-9_AZD4547_30min_R2 1 WETMDVRKLDFPSASFDVVLEK 22 2 P0DPD7;P0DPD8 P0DPD7 1 WET(1)MDVRKLDFPSASFDVVLEK 55.881 0.027725 0.0 3296.5 4117.1 4274.1 4169.7 5161.5 4760.5 1334.7 4714.8 3611.0 4624.0 True False 4344.718428540438 5447.872060721385 4217.422641352669 3208.4400862228167 4444.914818975269 4462.825182445985 1453.4857143434929 3986.2359953257414 3801.8700879973926 4462.11516743606 0.9736903386644146 1.2209169544702145 0.9451622118879573 0.7190401784421877 0.9961452477546261 1.0001591207271177 0.3257391752124293 0.8933512125408095 0.8520331603592282 1.0 12.123512034762443 -5.512338747646619 6.200159022715757 0.8162400040753868 1.0956880197449619 0.23046317477740874 0.1969491887301164 0.21017422850797793 33.957773543372774 0.05351113761634217 0.10328370320901059 3.0736984092341927e-06 5.512338747646619 0.2794480156695751 WGDEHIPGSPYR ddPTM_PC-9_Lapatinib_30min_R1 2 WGDEHIPGSPYR 12 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 ; 83.137 0.009526399999999999 36263000.0 383440.0 326540.0 347830.0 295850.0 321870.0 330220.0 278470.0 299910.0 343990.0 260090.0 False True 377972.07528571505 325783.916692557 319232.76006262837 317607.7959266681 302938.23942076735 316097.26038041734 292887.8140358256 313844.9134752833 305246.22382471256 305046.2099518601 1.239064977550003 1.0679821812700756 1.046506232983544 1.041179288792968 0.993089668180354 1.0362274634728335 0.96014244557258 1.0288438382001592 1.0006556838483063 1.0 18.218668280452057 -1.5228787452803412 0.8623914762919797 1.0062864450055224 89.60494988595798 0.9004997502554005 0.022811828424189363 194.206292926887 0.5093865369193862 0.007402007347337362 33786.40280065657 0.02999999999999975 1.5228787452803412 88.59866344095245 WGDYDSHDIER ddPTM_PC-9_AZD4547_30min_R2 4 WGDYDSHDIER 11 0 Q6P2Q9 Q6P2Q9 PRPF8 Pre-mRNA-processing-splicing factor 8 0 ;;; 151.79 0.00011630000000000001 16737600.0 118929.0 127608.0 161864.0 216166.0 171591.0 155909.0 150198.0 181816.0 140854.0 159278.0 False True 156745.94812312612 168854.7904895522 159717.57759994105 166332.26843140763 147768.55152625876 146159.98558344107 163565.33102791916 153720.51491604 148299.25488085966 153701.72570045022 1.0198060393193553 1.0985874733679557 1.0391397811057448 1.0821756728715792 0.9613981290896197 0.9509326256251197 1.0641736797847812 1.0001222446625382 0.9648509423367214 1.0 17.22977383754946 -6.256577245126778 24.970749887147566 0.9919830703827667 1.0612038695121564 0.4772572891605007 0.03568849706362466 374.14957474040517 1921542.9626528232 0.010850504113464247 0.013559560565540838 5.538890185498732e-07 6.256577245126778 0.06922079912938972 WGDYDSHDIER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WGDYDSHDIER 11 0 Q6P2Q9 Q6P2Q9 PRPF8 Pre-mRNA-processing-splicing factor 8 0 119.74 0.00078465 5916300.0 30075.0 39313.0 41406.0 37046.0 44970.0 33281.0 42620.0 37799.0 27879.0 25779.0 False True 35166.10349167363 43215.73482943426 42393.27607312944 34970.43272475249 36158.451319846085 31535.68577214791 38582.72505792102 36806.81630135102 28286.677633113788 30452.52863354827 1.1547843502536803 1.4191181083670439 1.3921102113808228 1.1483589144786825 1.1873710638272528 1.0355687093060104 1.2669793540696668 1.2086620702099102 0.9288777944683235 1.0 14.894274407208737 -6.9877820713190095 0.33653906950647083 0.9832599635226987 1.3648201141140688 0.41844526389533376 0.11520795501879866 1.8533723647345954 0.47924038926563783 0.15109406613171492 0.257628979676439 1.0285322854685728e-07 6.9877820713190095 0.38156015059137005 WGDYDSHDIER ddPTM_PC-9_Lapatinib_30min_R1 4 WGDYDSHDIER 11 0 Q6P2Q9 Q6P2Q9 PRPF8 Pre-mRNA-processing-splicing factor 8 0 ;;; 199.03 6.049e-05 16095800.0 146579.0 157325.0 172715.0 146622.0 178297.0 169828.0 160551.0 162780.0 183165.0 139981.0 False True 144488.7565807035 156960.72362851887 158515.03939918047 157405.07099665375 167809.92100538916 162564.8523284037 168863.5451979236 170343.3530576057 162535.02888704173 164176.52933704213 0.8800816850262373 0.9560484940346756 0.9655158385871403 0.9587550159104224 1.0221310054672184 0.9901832678815511 1.0285486353001128 1.037562151821979 0.9900016131621925 1.0 17.324888368730825 -2.686338466878892 0.45929309860869305 1.016828224958537 1.366607383855498e-09 0.797539824794145 0.01970811552615781 12.821111784297125 0.4341167510438286 0.012127039005046279 10.614026046367524 0.002059024589475681 2.686338466878892 -1.0168282235919295 WGLGGTCVNVGCIPK ddPTM_PC-9_Lapatinib_30min_R1 2 WGLGGTCVNVGCIPK 15 0 Q16881;Q16881-5;A0A182DWI3;Q16881-2;F8W809;Q16881-3;Q16881-6;Q16881-4;A0A087WSW9;E9PIR7;A0A087WSY9;Q16881-7;E2QRB9;E9PKD3;A0A0B4J225;E9PIZ5;E9PKI4;E9PLT3;A0A096LPD9;E7EWK1;A0A096LPK7;A0A182DWF2;Q9NNW7-2;D3YTF8;A0A182DWF3;Q9NNW7 Q16881 TXNRD1;TXNRD2 Thioredoxin reductase 1, cytoplasmic;Thioredoxin reductase 2, mitochondrial 0 ; 131.69 4.0515e-05 7589900.0 28884.0 26161.0 29630.0 25466.0 29101.0 28298.0 28257.0 25433.0 26890.0 27097.0 False True 28472.108863323112 26100.42581182705 27193.935775107602 27338.85459208566 27389.336394767313 27087.760505859904 29720.009197437153 26614.71002773125 23861.365035746756 31780.680345517067 0.8958936232257011 0.8212670568428765 0.8556750667215826 0.8602350325688366 0.8618234756774429 0.8523341920740491 0.9351596276204142 0.8374493477917466 0.7508135375431824 1.0 14.955862389087908 WGQPPS(ph)PTPVPRPPDADPNTPSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WGQPPSPTPVPRPPDADPNTPSPK 24 1 Q14839-2;A0A2R8Y8C1;A0A0C4DGG9;A0A2R8Y521;A0A2R8Y212;F5GWX5;A0A2U3TZM0;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8YER1;Q14839;A0A2R8YDJ9;A0A2R8YD40;A0A2R8YFD8;A0A2R8Y5Z7;A0A2R8Y685;A0A2R8Y8B3 Q14839-2 CHD4 Chromodomain-helicase-DNA-binding protein 4 1 WGQPPS(0.822)PT(0.176)PVPRPPDADPNT(0.001)PS(0.001)PK 44.953 0.025713 9786200.0 23841.0 36230.0 23179.0 27460.0 25929.0 16796.0 23241.0 16962.0 19646.0 22186.0 True False 27876.81041878606 39826.674964271435 23731.67526684701 25921.50522652119 20848.398582883903 15915.188192331852 21039.444229731183 16516.76547272456 19933.28558341955 26208.146175720645 1.063669678575407 1.5196296104745883 0.9055075894239384 0.9890629063468441 0.795493067044855 0.6072611197153563 0.8027826191393204 0.6302149477487947 0.7605759464927682 1.0 14.677727688283223 -5.687173891263994 1.4521662236373942 0.7445747905655347 1.2877834046718772 0.5657858792983559 0.16492601272766919 0.2739302860343765 1.1439482047925589 0.0505932649038886 0.13052393964452896 2.0550675833345868e-06 5.687173891263994 0.5432086141063426 WGQPPSPTPVPRPPDADPNTPS(ph)PKPLEGRPER ddPTM_PC-9_AZD4547_30min_R2 1 WGQPPSPTPVPRPPDADPNTPSPKPLEGRPER 32 3 Q14839-2;A0A2R8Y8C1;A0A0C4DGG9;A0A2R8Y521;A0A2R8Y212;F5GWX5;A0A2U3TZM0;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8YER1;Q14839;A0A2R8YDJ9;A0A2R8YD40;A0A2R8YFD8;A0A2R8Y5Z7;A0A2R8Y685;A0A2R8Y8B3 Q14839-2 CHD4 Chromodomain-helicase-DNA-binding protein 4 1 WGQPPS(0.002)PT(0.008)PVPRPPDADPNT(0.247)PS(0.744)PKPLEGRPER 46.847 0.011877 6235600.0 10638.0 10911.0 11414.0 12386.0 11258.0 12259.0 11700.0 11231.0 10925.0 10640.0 True False 14020.662715854156 14437.76737376578 11262.642902224889 9530.5990617924 9695.021027225333 11492.442792060778 12741.277334096705 9495.50701270539 11502.47319617045 10267.496838563951 1.3655385471552905 1.4061623393482436 1.096921974197571 0.9282300459052669 0.944243877515653 1.1193032705786692 1.2409331635965466 0.9248122655408059 1.120280178998256 1.0 13.325796882650318 -5.313580546166946 4.5953855739311 1.0428006979543296 1.3882165791737433 0.6696496030348922 0.09569613091301724 0.11652446158261695 5.352872102243248 0.026538160239694013 0.0604525603960868 4.857574318704114e-06 5.313580546166946 0.3454158812194137 WGRDDIENIAR ddPTM_PC-9_AZD4547_30min_R2 1 WGRDDIENIAR 11 1 O60264 O60264 SMARCA5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 0 84.821 0.015295 4053800.0 12406.0 12953.0 17340.0 18963.0 17722.0 17612.0 18485.0 15344.0 16884.0 16891.0 False True 16350.849939169626 17139.80394027937 17110.060270245274 14591.373325429473 15261.606203987145 16510.718855842606 20130.12918981004 12972.937370042879 17776.45377063085 16299.651231220276 1.003141092237071 1.0515442138694273 1.0497194097915878 0.895195432002939 0.9363148933368056 1.0129492110983365 1.2350036761064485 0.795902758041508 1.0906033214122959 1.0 13.992553474535121 -6.992258823552556 24.877243659456997 1.029170346615697 0.9876734129993322 0.03343890059512944 0.10989283664432745 808.2693524509583 2597461.8656875375 0.0389668388453648 0.0342969349237813 1.017984525867912e-07 6.992258823552556 -0.04149693361636475 WGRDDIENIAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 WGRDDIENIAR 11 1 O60264 O60264 SMARCA5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 0 ; 98.898 0.010662 2328400.0 17476.0 16971.6 19945.4 25911.3 25228.4 24521.0 23136.3 22501.4 21988.1 16875.8 False True 20434.341633266456 18656.428286603074 20420.97397935074 24459.573866568036 20285.076123584746 23235.07559324656 20944.66217169353 21910.76209220403 22309.634365101658 19935.248951240712 1.0250356884554823 0.9358512819295368 1.0243651348070975 1.226951011567164 1.0175481717434114 1.1655272352041772 1.0506345931732142 1.0990964871216402 1.1191048789843767 1.0 14.283034001362134 -5.532469687173496 24.998667519786476 1.100796537441846 0.9803596400207395 0.3430313956638389 0.06635246518717335 181.7782777395258 473801.3305349931 0.016539751624930845 0.02869158393170905 2.9344743168428215e-06 5.532469687173496 -0.12043689742110653 WGY(ph)KCCHS(ph)FFKY(ph)SYCTGEAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WGYKCCHSFFKYSYCTGEAGK 21 2 O95391 O95391 SLU7 Pre-mRNA-splicing factor SLU7 3 WGY(0.999)KCCHS(0.998)FFKY(0.751)S(0.086)Y(0.08)CT(0.086)GEAGK 47.751999999999995 0.044453 5699800.0 9735.2 11286.0 10840.0 12028.0 12866.0 10829.0 12430.0 9816.6 10494.0 8392.0 True False 11383.177081035456 12406.399493424442 11098.466710928933 11354.110155302145 10344.999659353793 10261.108176635007 11252.540414593119 9558.924651547453 10647.454897302488 9913.403168964554 1.1482612869687632 1.2514773465750488 1.119541546103401 1.1453292034816003 1.0435366627416525 1.0350742325056441 1.1350835049078747 0.9642424996365677 1.0740463911158176 1.0 13.275164689416066 -5.960607745910617 1.2076844305611893 1.0402644933789704 1.1982143703234949 0.5833936556322641 0.05193910653425097 0.3309820485744604 0.9790518909573708 0.018680101035895822 0.03784366801774428 1.0949448722737626e-06 5.960607745910617 0.15794987694452445 WHEGY(ph)RQTPK ddPTM_PC-9_Lapatinib_30min_R1 1 WHEGYRQTPK 10 1 P16070;P16070-5;P16070-7;P16070-3;P16070-4;P16070-8;P16070-9;H0YCL4;H0YEU1;H0YDV8 P16070;H0YDV8 CD44 CD44 antigen 1 WHEGY(0.999)RQT(0.001)PK 94.85 0.015396 0.0 34698.0 30633.0 32459.0 26539.0 33204.0 33150.0 33148.0 29308.0 31811.0 22595.0 True False 34203.20015716612 30562.071170585896 29790.346315363404 28490.766591508716 31251.00600157569 31732.25177642433 34864.241245590325 30669.756674114255 28228.11019531946 26500.51564405499 1.2906616843449652 1.1532632640467906 1.1241421380435077 1.0751023479763953 1.1792602989816314 1.197420163540969 1.3156061457019843 1.157326788884373 1.0651909787141078 1.0 14.693732811296359 -8.3654554740566 2.8710237652324806 1.0054478864594325 1.184944966705037 0.4681873723620702 0.06763422291581889 0.24722606362030822 3.79948105528029 0.06929077539278923 0.01891862738020457 4.310667507605273e-09 8.3654554740566 0.1794970802456044 WHQPPPS(ph)PLPLR ddPTM_PC-9_AZD4547_30min_R2 2 WHQPPPSPLPLR 12 0 J3QQY0;J3KSZ8;Q68DK7;Q68DK7-2;J3KTC2;Q68DK7-3 J3QQY0 MSL1 Male-specific lethal 1 homolog 1 WHQPPPS(1)PLPLR;WHQPPPS(1)PLPLR 92.611 0.0032683 14082300.0 25755.1 22737.9 34331.0 37544.0 34556.0 36037.0 28227.8 36044.8 34028.0 30677.0 True False 33944.68606064064 30087.481511130856 33875.74850852309 28888.810849017762 29758.49587997854 33783.600693163746 30740.01951550553 30474.90438710385 35826.650610461176 29603.007567352095 1.1466634254445416 1.016365700095725 1.1443346907049816 0.9758741838406314 1.0052524498489785 1.141221905115555 1.0384086632267526 1.029452981011069 1.2102368493792122 1.0 14.853456135879432 WHQPPPS(ph)PLPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 WHQPPPSPLPLR 12 0 J3QQY0;J3KSZ8;Q68DK7;Q68DK7-2;J3KTC2;Q68DK7-3 J3QQY0 MSL1 Male-specific lethal 1 homolog 1 WHQPPPS(1)PLPLR;WHQPPPS(1)PLPLR 96.229 0.0024646 13769700.0 45616.0 44306.0 35927.0 40115.0 55494.0 42815.0 49232.0 47843.0 36159.0 41285.0 True False 53337.887842932134 48704.4068718468 36783.635933906255 37867.48660458476 44620.34906701225 40569.706028500164 44568.38855118651 46587.171943848676 36687.75696889275 48769.64368811983 1.0936698283880453 0.998662347900464 0.7542322057781746 0.7764560849930751 0.9149205467310326 0.8318639005841835 0.9138551193074076 0.9552493809832201 0.7522662499547808 1.0 15.573695811606225 -5.042981334955991 5.284984525222803 0.860471543459604 1.0748416664968454 0.469177634181711 0.08102621685066277 0.14267021562303275 9.930155016785253 0.020451106514514164 0.062450724952549906 9.057715281764586e-06 5.042981334955991 0.21437012303724146 WHQPPPS(ph)PLPLR ddPTM_PC-9_Lapatinib_30min_R1 2 WHQPPPSPLPLR 12 0 J3QQY0;J3KSZ8;Q68DK7;Q68DK7-2;J3KTC2;Q68DK7-3 J3QQY0 MSL1 Male-specific lethal 1 homolog 1 WHQPPPS(1)PLPLR;WHQPPPS(1)PLPLR 94.53200000000001 0.0027653 11220800.0 24758.0 29168.0 33413.0 26844.0 30384.0 27414.0 30755.0 28264.0 31868.0 28438.0 True False 24404.946379938847 29100.463288076575 30665.91211790987 28818.197308958876 28596.87285724237 26241.567125155238 32347.34341462925 29577.248622804862 28278.690255082867 33353.4704087469 0.7317063586144452 0.8724868186563585 0.9194219294753742 0.8640239518044678 0.8573882269757117 0.7867717153137211 0.9698344135771312 0.8867817429591456 0.8478485119697415 1.0 15.025549260329797 -14.52287874526902 0.09679877783841574 1.4136011939911843 0.7698489974370153 0.37735548856028767 0.059156287756710446 232.8283169505684 1.5383502105705866 19.79252006898166 1.1364214778022985 3.0000000000781775e-15 14.52287874526902 -0.643752196554169 WIDNPTVDDR ddPTM_PC-9_AZD4547_30min_R2 1 WIDNPTVDDR 10 0 P18206;P18206-2 P18206 VCL Vinculin 0 130.98 0.00089813 3039200.0 13771.0 12723.0 21756.0 19127.0 20925.0 15533.0 17247.0 20855.0 15402.0 17635.0 False True 18149.891545405866 16835.4609381745 21467.501224882133 14717.565659204201 18019.92494179162 14561.719054497105 18781.94958813383 17632.33895022447 16216.118276193796 17017.60401767624 1.0665362483786505 0.989296784711141 1.2614878805843508 0.8648435845561466 1.0588990625868522 0.8556856205710158 1.103677672169652 1.0361234714305083 0.95290255075568 1.0 14.05474030757538 -5.777239413231416 24.999990939730868 0.9862826104721161 1.094126059149428 0.25172687713923825 0.09716208476686441 359.556139576711 568916.012350937 0.02649389799829641 0.03944842666070076 1.6701696471682765e-06 5.777239413231416 0.10784344867731188 WIDNPTVDDR ddPTM_PC-9_Lapatinib_30min_R1 2 WIDNPTVDDR 10 0 P18206;P18206-2 P18206 VCL Vinculin 0 ; 182.46 0.0049061999999999995 8181200.0 76024.0 84703.0 89750.0 73923.0 80574.0 78509.0 75905.0 78448.0 89927.0 67104.0 False True 74939.88381890579 84506.87540763673 82371.10144501895 79359.54401989882 75834.79573457889 75151.35308341772 79834.98949398263 82092.98046850383 79798.47428670886 78702.8369895403 0.9521878331891058 1.0737462414330476 1.0466090498868061 1.0083441341567623 0.9635586039250075 0.954874766374755 1.0143851549416547 1.0430752385636883 1.0139211919046092 1.0 16.264128020834583 -11.143124295514827 14.34100144495524 0.9999999666489277 1.0093147009531773 0.002411775554931217 0.03879528701514175 4.40672120265526e-08 1.1427429640812675e-09 0.039992050690168396 0.009699462322528388 7.192431004496437e-12 11.143124295514827 0.009314734304249672 WISENQDSADVDPQEHS(ph)FTR ddPTM_PC-9_AZD4547_30min_R2 2 WISENQDSADVDPQEHSFTR 20 0 Q15751 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 WISENQDSADVDPQEHS(0.866)FT(0.134)R;WISENQDSADVDPQEHS(0.974)FT(0.026)R 128.25 8.6004e-06 7469500.0 38781.0 36548.0 48018.0 54567.0 44950.0 51032.0 42607.0 50500.0 45413.0 45791.0 True False 51112.5513050893 48361.426264906186 47381.24994559613 41987.42120174601 38709.468393478324 47840.96097270949 46398.94045930408 42696.38537455459 47813.438467523025 44187.87102769563 1.1567099775649632 1.094450244832902 1.0722682230130296 0.9502024022707397 0.8760202176116697 1.082671779835788 1.0500379262495496 0.9662467184217537 1.0820489278054377 1.0 15.431362803249574 -5.394497086925069 2.50139641765775 1.0006250841789566 1.1324180811727307 0.40081151384300506 0.06135653162007771 0.3103088917237722 3.708453119659594 0.01795325036704605 0.048381898080870005 4.03183650830225e-06 5.394497086925069 0.13179299699377411 WISENQDSADVDPQEHS(ph)FTR ddPTM_PC-9_Lapatinib_30min_R1 1 WISENQDSADVDPQEHSFTR 20 0 Q15751 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 WISENQDSADVDPQEHS(0.742)FT(0.258)R 89.272 0.00039454 4112900.0 7575.5 8818.4 8106.5 7774.2 9368.6 7752.2 6592.1 5332.4 8275.5 5226.1 True False 7467.471980823442 8797.981536600884 7440.014861994928 8345.94060197095 8817.55736737628 7420.656477260836 6933.406682606979 5580.162770883264 7343.426045121693 6129.424421659474 1.2182990550361834 1.4353683039979352 1.2138194959553192 1.3616189755891268 1.4385620509843928 1.2106612247372772 1.1311676603934429 0.910389359099479 1.1980612762223344 1.0 12.581535889898772 -7.196385240572923 2.482887494385434 1.0423304753867022 1.3327881681420823 0.6230088040290875 0.10019526223107596 0.18320563803714685 2.2140257962580163 0.043101737731352445 0.030058497516230735 6.362309024094746e-08 7.196385240572923 0.29045769275538014 WISIMTER ddPTM_PC-9_AZD4547_30min_R2 2 WISIMTER 8 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YN28;H0YNP5;H0YL33 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ; 124.59 0.015491999999999999 15434300.0 35049.0 32730.0 49229.0 61986.0 60965.0 51542.0 35718.0 56946.0 45216.0 44464.0 False True 46193.85293551155 43309.332429965536 48576.19129434279 47696.08537415338 52501.062082500684 48319.07059208718 38896.832805065475 48146.304188898685 47606.025449706496 42907.32889378832 1.0765958666375763 1.0093691112111016 1.1321187439699876 1.1116069586204964 1.2235919465520784 1.1261262781399173 0.9065312105852518 1.1220997771284897 1.109508018258354 1.0 15.388936471462328 WISIMTER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WISIMTER 8 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YN28;H0YNP5;H0YL33 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 93.195 0.031855 0.0 11534.0 11635.0 11502.0 15382.0 16018.0 11888.0 13623.0 14259.0 14412.0 11726.0 False True 13486.478393115998 12790.04590696379 11776.251301577915 14520.19640911685 12879.387886175107 11264.572352372052 12332.530818021085 13884.71635865933 14622.748235174719 13851.830977035072 0.9736242389526127 0.9233469516173267 0.8501584607191456 1.0482510531055325 0.9297967833658831 0.8132190156700272 0.8903177376671119 1.002374081930308 1.0556545383363216 1.0 13.75778906823527 -7.879064990853579 5.1076529079808255 1.0278320766626008 0.9175987530136882 0.3622202570669496 0.06183830307785155 0.23594223646382734 9.44061818140088 0.037009906383494204 0.017242469133982207 1.321097921091561e-08 7.879064990853579 -0.11023332364891258 WISIMTER ddPTM_PC-9_Lapatinib_30min_R1 2 WISIMTER 8 0 P07355;P07355-2;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YN28;H0YNP5;H0YL33 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 ; 153.04 0.00051874 32404000.0 78934.0 63722.0 72446.0 69278.0 69195.0 68651.0 59842.0 50514.0 82610.0 55338.0 False True 77808.38668527716 63574.45562406802 66489.76952964709 74372.93522463326 65125.08614260412 65714.95676329738 62940.32595084519 52861.06485042331 73305.59187813458 64903.09956674997 1.1988393035875686 0.9795288059961528 1.024446751749742 1.1459072944296596 1.0034202769565088 1.0125087584717345 0.9697583993829731 0.8144613308653779 1.129462111478097 1.0 15.985999757971083 -6.6647756869553065 2.108637489292037 0.9678966573833394 1.0744183423967857 0.1975289097992865 0.09238705239650191 0.5046880707315691 4.597674439240982 0.03450429487460033 0.03386514205659328 2.163835856095764e-07 6.6647756869553065 0.10652168501344628 WIVEER ddPTM_PC-9_AZD4547_30min_R2 1 WIVEER 6 0 O95433;O95433-2;G3V3W9 O95433 AHSA1 Activator of 90 kDa heat shock protein ATPase homolog 1 0 134.12 0.026723 12476000.0 22817.0 19306.0 30948.0 39913.0 35083.0 27849.0 26070.0 34619.0 23203.0 24907.0 False True 30072.331376917107 25546.28695059317 30537.60929893602 30711.674499702924 30212.331026660722 26107.597627547166 28390.179495718017 29269.429015479305 24429.463210136662 24035.013511100784 1.2511884531717836 1.062877994172726 1.2705467914478996 1.2777889425990323 1.2570132741014224 1.086231868165547 1.1812008960430067 1.2177829233156436 1.016411461506094 1.0 14.552849994025575 -8.267014513519502 22.836403446511035 1.0082055706319208 1.1983184448118491 0.544562515532026 0.07034690970115011 116.1005511118763 475535.45945054176 0.06273243533220539 0.018177725864797042 5.407362519877363e-09 8.267014513519502 0.19011287417992828 WIYEDVER ddPTM_PC-9_AZD4547_30min_R2 2 WIYEDVER 8 0 O43852;O43852-3;O43852-5;O43852-13;O43852-14;O43852-11;O43852-10;O43852-6 O43852 CALU Calumenin 0 ; 141.39 0.010416 17432500.0 60237.0 62490.0 95319.0 125463.0 100787.0 86400.0 74745.0 97845.0 75250.0 80901.0 False True 79391.1129925649 82688.67044144649 94055.0077796718 96539.44373402723 86794.46476025596 80997.39434163086 81397.1601997486 82725.30350442174 79227.56137408031 78068.68061434782 1.0169393458146139 1.0591785308877064 1.2047726058583592 1.2365963274174352 1.1117706111752128 1.0375145795245422 1.0426352739563152 1.0596477723644033 1.0148443748583027 1.0 16.252456267422268 -6.709161924496378 4.488912842122195 1.0349121998377089 1.1344135681497955 0.37630915112410834 0.061042863907069915 0.255022194416609 10.68202517905895 0.023351120057897586 0.02272550046781978 1.953610926037529e-07 6.709161924496378 0.09950136831208667 WIYEDVER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 WIYEDVER 8 0 O43852;O43852-3;O43852-5;O43852-13;O43852-14;O43852-11;O43852-10;O43852-6 O43852 CALU Calumenin 0 ;; 119.17 0.015992 9228700.0 43134.0 41275.0 44072.0 54313.0 57914.0 49346.0 55406.0 44447.0 46676.0 39842.0 False True 50435.734264666666 45372.50922302799 45122.84362399075 51270.01869512183 46566.16743912755 46758.20889133173 50157.54257529737 43280.313345489274 47358.54819768353 47065.03921090151 1.0716178103806704 0.9640384876704515 0.9587337943519467 1.08934401319369 0.9894003748825433 0.9934807167971357 1.065707017698172 0.9195851968070688 1.006236242266086 1.0 15.522368176426262 -7.759845516980826 24.999991934217224 0.9721830528526971 1.0150755337693915 0.14454475013990964 0.04783414176808413 83.21283443112557 1305285.6528784018 0.023360178519540312 0.01256992253397316 1.7384190923532675e-08 7.759845516980826 0.0428924809166944 WIYEDVER ddPTM_PC-9_Lapatinib_30min_R1 4 WIYEDVER 8 0 O43852;O43852-3;O43852-5;O43852-13;O43852-14;O43852-11;O43852-10;O43852-6 O43852 CALU Calumenin 0 ;;; 143.89 0.0077832 22321300.0 119948.0 94851.0 115563.0 93216.0 92635.0 109233.0 92061.0 87778.0 109033.0 87356.0 False True 118237.51952423049 94631.3783371282 106061.85622608024 100071.41559946036 87186.39142741726 104561.35922455974 96827.4681220675 91856.48632934358 96752.5553716094 102455.36820544678 1.154039281642489 0.9236351398139563 1.03520057644419 0.9767317940705065 0.8509694802188238 1.0205552042416164 0.9450697393220623 0.8965512294597392 0.9443385648431626 1.0 16.644636051567616 WKDSDEADLVLAK ddPTM_PC-9_AZD4547_30min_R2 2 WKDSDEADLVLAK 13 1 Q13185 Q13185 CBX3 Chromobox protein homolog 3 0 ; 138.55 8.3665e-05 15604500.0 136665.0 111487.0 163195.0 191673.0 181436.0 172442.0 149958.0 171334.0 125447.0 167924.0 False True 180121.62719140848 147522.99250288916 161030.92767028144 147485.75116833008 156246.7432133289 161659.17447985546 163303.9714928613 144858.26716364254 132077.87231487376 162045.03187208757 1.1115529128569022 0.9103826929994276 0.9937418371295293 0.910152872102552 0.9642180411718169 0.9976188261511363 1.0077690726227726 0.8939383422627135 0.8150689397199861 1.0 17.306035264278776 -7.774960268887527 23.930643403749695 0.8908776280682253 0.9793239573901528 0.22548587762868655 0.06801907386938238 193.61495830346917 342671.0803799223 0.03506335460793516 0.017010727696323037 1.6789576093035956e-08 7.774960268887527 0.08844632932192742 WKDSDEADLVLAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 WKDSDEADLVLAK 13 1 Q13185 Q13185 CBX3 Chromobox protein homolog 3 0 ; 110.51 0.00086643 13186000.0 121229.0 119532.0 121252.0 145884.0 160278.0 141916.0 155860.0 147956.0 130149.0 120966.0 False True 141750.6753181079 131398.34700053246 124143.10753077084 137710.59244230937 128872.67646525019 134473.6751311603 141095.81247131774 144072.31177234033 132052.18290728264 142896.17823367091 0.9919836700342691 0.9195371676467328 0.8687643649067078 0.963710815394364 0.9018623035145923 0.9410585838850237 0.9874008823426395 1.0082306857552632 0.9241127687218084 1.0 17.124607806426447 -7.143572492928574 4.38311712595807 0.9804251271665495 0.9267864768236672 0.2904885648488581 0.03750982594539425 0.29072576892051427 9.104813142970238 0.014620854732013022 0.011182429684813762 7.185012153306504e-08 7.143572492928574 -0.05363865034288229 WKDSDEADLVLAK ddPTM_PC-9_Lapatinib_30min_R1 2 WKDSDEADLVLAK 13 1 Q13185 Q13185 CBX3 Chromobox protein homolog 3 0 ; 128.96 0.00012771 11777900.0 167694.0 149324.0 167353.0 143165.0 157256.0 138126.0 152679.0 142365.0 157705.0 130016.0 False True 165302.652808687 148978.24945243908 153593.88234126134 153693.83168443997 148006.5112571916 132218.67296743256 160583.97155591546 148979.79762898426 139942.60219272756 152489.09236456983 1.0840293574145132 0.9769764324930399 1.007245042642461 1.0079004950530484 0.97060392295692 0.867069709165329 1.053084971953223 0.9769865851965623 0.9177220483295538 1.0 17.218346523969082 -1.522880831485805 0.8506505260747232 0.9692257969595219 38.556858146357314 0.3006332280588774 0.049079728587441494 892.6224792276822 2.479734009702451 0.017092719243834174 64929.50402105333 0.029999855890377812 1.522880831485805 37.58763234939779 WKEPGSGGPQNLS(ph)GPGGR ddPTM_PC-9_AZD4547_30min_R2 3 WKEPGSGGPQNLSGPGGR 18 1 Q9H0W8-2;Q9H0W8;M0QZH1;M0QX70;M0QYR7;M0R2N0;M0QZC7 Q9H0W8-2 SMG9 Protein SMG9 1 WKEPGSGGPQNLS(1)GPGGR;WKEPGSGGPQNLS(1)GPGGR;WKEPGSGGPQNLS(1)GPGGR 83.727 0.00098577 68465500.0 143119.0 180126.0 217725.0 273506.0 248564.0 206736.0 191368.0 240245.0 166262.0 189643.0 True False 188627.8649398691 238348.20694408705 214837.82424101242 210453.41732557674 214055.17912695344 193808.76523855753 208399.38127106123 203120.65553088803 175050.2698893998 183003.65629283656 1.030732766552122 1.3024231961939052 1.17395372635198 1.1499956972926046 1.1696770625414676 1.0590431315122524 1.1387716808105037 1.1099267612766213 0.9565397404371527 1.0 17.48151294733328 -7.7911668434972565 0.6912149146737835 0.9810863538870642 1.1748420820953491 0.4277943727430483 0.07240842490018101 0.63592538699111 0.6017333810663641 0.06577997333680694 0.032501297297333163 1.617458537040176e-08 7.7911668434972565 0.1937557282082849 WKEPGSGGPQNLS(ph)GPGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 WKEPGSGGPQNLSGPGGR 18 1 Q9H0W8-2;Q9H0W8;M0QZH1;M0QX70;M0QYR7;M0R2N0;M0QZC7 Q9H0W8-2 SMG9 Protein SMG9 1 WKEPGSGGPQNLS(1)GPGGR;WKEPGS(0.002)GGPQNLS(0.998)GPGGR;WKEPGSGGPQNLS(1)GPGGR;WKEPGS(0.002)GGPQNLS(0.998)GPGGR 71.042 0.004442100000000001 77160000.0 128559.0 125169.0 125576.0 142583.0 155141.0 122097.0 152586.0 135189.0 116729.0 95725.0 True False 150321.49954400893 137594.95110689767 128570.20808963175 134594.5367703229 124742.2347389872 115694.01838051587 138131.94945302518 131640.43199458555 118435.94079542808 113079.18474131715 1.3293472170664147 1.2168017608339097 1.1369927045702732 1.1902680150924756 1.1031405561010255 1.0231239166180803 1.2215506308169748 1.1641438014938787 1.0473717251001162 1.0 16.786973861463686 -1.5228787453943968 0.5332441300723061 1.1014087482452366 10.13254437343849 0.55554199649968 0.06484667486883179 102.25090128798018 0.9865453639986494 0.033753106763395845 1050.469778488787 0.029999999992121065 1.5228787453943968 9.031135625193254 WKEPGSGGPQNLS(ph)GPGGR ddPTM_PC-9_Lapatinib_30min_R1 4 WKEPGSGGPQNLSGPGGR 18 1 Q9H0W8-2;Q9H0W8;M0QZH1;M0QX70;M0QYR7;M0R2N0;M0QZC7 Q9H0W8-2 SMG9 Protein SMG9 1 WKEPGSGGPQNLS(1)GPGGR;WKEPGSGGPQNLS(1)GPGGR;WKEPGSGGPQNLS(1)GPGGR;WKEPGSGGPQNLS(1)GPGGR 98.76 0.00032609 89562000.0 311935.0 271465.0 288254.0 237934.0 247055.0 246036.0 211264.0 222375.0 243164.0 183753.0 True False 307486.74969812686 270836.4394712602 264554.8688126181 255432.46008455555 232523.71062881843 235513.61381792877 222202.21619730897 232707.35431984995 215776.309689562 215514.46121451762 1.4267569237131719 1.2566972904972555 1.2275504266476434 1.1852219041129892 1.0789239353983315 1.0927972651612667 1.0310315834264807 1.0797760531170062 1.0012149925975675 1.0 17.717425153136276 -1.5228787452804977 0.2993756092340614 0.9990114877901276 4.6014032561616665 0.9551148380269706 0.027283120376379737 9.72013840340597 0.13849071920741926 0.026816809816365257 18.738740515909136 0.02999999999998894 1.5228787452804977 3.6023917683715387 WLAES(ph)PVGLPPEEEDKLTR ddPTM_PC-9_AZD4547_30min_R2 2 WLAESPVGLPPEEEDKLTR 19 1 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 WLAES(0.998)PVGLPPEEEDKLT(0.002)R;WLAES(1)PVGLPPEEEDKLTR 70.072 0.0034373000000000003 11512400.0 23276.6 23610.3 31170.0 37550.0 38826.0 36688.0 29008.0 38440.0 28280.0 31048.0 True False 30678.07461664321 31241.867750419016 30756.665433883783 28893.42764171686 33435.680085543696 34393.893560251716 31589.655804057875 32499.981263324324 29774.82306523573 29961.018970275716 1.0239329525834513 1.042750507965501 1.0265560548657382 0.964367322432591 1.1159727283880159 1.1479547339285705 1.0543585261702189 1.0847421876928656 0.9937853947749671 1.0 14.870799070047214 -6.268173620117719 24.995302154635624 1.073874806264586 1.0172947910164114 0.20623767461556441 0.048176764751964904 806.4067318921725 2993110.300716155 0.015185870078678828 0.017628186552624485 5.392949827113936e-07 6.268173620117719 -0.056580015248174576 WLAES(ph)PVGLPPEEEDKLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WLAESPVGLPPEEEDKLTR 19 1 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 WLAES(1)PVGLPPEEEDKLTR 76.186 0.0017948 4136600.0 21929.0 21292.0 25047.0 32367.0 27836.0 23605.0 32074.0 26373.0 23028.0 22662.0 True False 25641.14658250743 23405.729046074168 25644.21547127645 30553.581925229824 22381.735622397966 22367.1122457724 29035.718524349115 25680.73669450329 23364.740935304148 26770.441207706703 0.9578156140036209 0.874312412876337 0.9579302512165532 1.1413178321631108 0.8360615145914998 0.8355152637280155 1.0846186022511382 0.9592944880979509 0.8727813170512065 1.0 14.708353296000126 -10.911913716062065 5.205561517357672 1.0000340125808327 0.9484703603788633 0.026615786068453606 0.09625139537047481 3.8682449965529755e-05 4.5400645836208336e-06 0.09488322826812115 0.022997386886050162 1.2248595254175945e-11 10.911913716062065 -0.051563652201969346 WLAES(ph)PVGLPPEEEDKLTR ddPTM_PC-9_Lapatinib_30min_R1 3 WLAESPVGLPPEEEDKLTR 19 1 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 WLAES(1)PVGLPPEEEDKLTR;WLAES(1)PVGLPPEEEDKLTR;WLAES(1)PVGLPPEEEDKLTR 85.166 0.00061854 9880600.0 59328.4 54659.0 56784.1 48718.8 60773.2 59264.3 52183.4 50207.2 58934.3 42511.7 True False 58482.366136503915 54532.440443738924 52115.53049096478 52301.743073152546 57198.639860708354 56729.70404083092 54885.20111666279 52540.00980239487 52296.4985283083 49859.79070172042 1.1729364546748082 1.0937157913472202 1.0452416618180174 1.048976386323817 1.1471897305564642 1.1377846405374792 1.1007908445706527 1.0537551213704146 1.0488712004662266 1.0 15.605589206337472 -8.219124154851794 1.4147912052956235 1.0062164811985865 1.1042455914826723 0.44099002932246956 0.038919651950522695 0.4278371260158801 1.619831048368109 0.039573069971557254 0.012387203997477022 6.037759989637602e-09 8.219124154851794 0.09802911028408579 WLDDLLAS(ph)PPPSGGGAR ddPTM_PC-9_AZD4547_30min_R2 6 WLDDLLASPPPSGGGAR 17 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 WLDDLLAS(0.988)PPPS(0.012)GGGAR;WLDDLLAS(1)PPPSGGGAR;WLDDLLAS(0.999)PPPS(0.001)GGGAR;WLDDLLAS(0.999)PPPS(0.001)GGGAR;WLDDLLAS(1)PPPSGGGAR;WLDDLLAS(0.998)PPPS(0.002)GGGAR 191.44 6.8306999999999996e-09 457102000.0 152039.5 144743.8 187647.40000000002 280936.0 244604.3 204848.8 175867.09999999998 230914.3 181412.5 203651.5 True False 200384.89838194236 191529.40273071945 185159.0728693669 216170.54561793257 210645.2151225555 192039.57215289134 191518.93120028373 195231.800817733 191001.59438904098 196521.72297169265 1.019657752597692 0.974596598454959 0.9421812004774534 1.099982955314666 1.0718673332255346 0.9771925935157462 0.9745433141142898 0.9934362362874996 0.971910847822931 1.0 17.584329267283913 -9.70931602796344 10.983004319548458 0.9999978056896673 1.003232550788896 0.00026126056237663065 0.046332078591920484 0.0 0.0 0.04830474139311895 0.011715620645998534 1.952917836848845e-10 9.70931602796344 0.0032347450992286086 WLDDLLAS(ph)PPPSGGGAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 WLDDLLASPPPSGGGAR 17 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 WLDDLLAS(0.648)PPPS(0.352)GGGAR;WLDDLLAS(0.995)PPPS(0.005)GGGAR;WLDDLLAS(0.944)PPPS(0.056)GGGAR;WLDDLLAS(0.999)PPPS(0.001)GGGAR;WLDDLLAS(0.973)PPPS(0.027)GGGAR;WLDDLLAS(0.97)PPPS(0.03)GGGAR;WLDDLLAS(0.998)PPPS(0.002)GGGAR;WLDDLLAS(1)PPPSGGGAR 172.42 9.0351e-06 245570800.0 53685.4 52353.63 58593.8 63451.95 76998.07999999999 68040.20000000001 71200.06 70704.91 63800.5 51031.350000000006 True False 62773.277885017305 57550.952393312975 59990.89841022394 59896.942955497456 61910.85895934215 64472.05213407342 64455.4748730052 68848.98103054463 64733.46161381237 60282.92979105571 1.041310999690846 0.9546807461546423 0.9951556538170264 0.9935970790255865 1.027004811709201 1.0694910210492001 1.0692160300836702 1.1420974605776357 1.0738273975432593 1.0 15.879461914141336 -6.637331650957361 1.925672369749519 1.0825430077105451 0.9924798823690922 0.4530083047948037 0.037995490979646614 0.2593303861041072 1.9700720904995697 0.014252486280420092 0.014263534956237951 2.3049863031722605e-07 6.637331650957361 -0.09006312534145289 WLDDLLAS(ph)PPPSGGGAR ddPTM_PC-9_Lapatinib_30min_R1 6 WLDDLLASPPPSGGGAR 17 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 WLDDLLAS(0.999)PPPS(0.001)GGGAR;WLDDLLAS(0.965)PPPS(0.035)GGGAR;WLDDLLAS(0.961)PPPS(0.039)GGGAR;WLDDLLAS(0.996)PPPS(0.004)GGGAR;WLDDLLAS(1)PPPSGGGAR;WLDDLLAS(1)PPPSGGGAR 223.68 7.240000000000002e-29 386937600.0 122429.20000000001 104923.5 112025.7 100680.6 119048.9 115526.7 104349.9 110899.9 124309.1 98106.29999999999 True False 120683.33715723432 104680.55608223048 102815.37937770756 108084.98718463576 112046.67776114267 110585.89234689099 109752.62723401787 116052.71421398938 110308.10012514498 115063.84323657257 1.0488380516641358 0.9097606436368205 0.8935507148524316 0.9393479666971647 0.9737783356564357 0.9610829017724112 0.9538411385092119 1.0085941069722804 0.9586686575238954 1.0 16.812075037897323 -7.286356884620057 1.0003969197658578 0.9882965305784899 0.9450779906779069 0.10125337459978778 0.04156734679362513 1.1781547027598676 2.279218165549595 0.031386491360469795 0.01753708839014669 5.1718165952468396e-08 7.286356884620057 -0.043218539900583 WLDES(ph)DAEMELR ddPTM_PC-9_AZD4547_30min_R2 22 WLDESDAEMELR 12 0 H3BPZ1;H3BS72;Q9P035 H3BPZ1 HACD3 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 1 WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR 186.16 2.4530000000000004e-35 35388600.0 409419.02 508200.33 666123.7 452682.6000000001 491263.8999999999 374099.7 522780.69999999995 580706.6 476951.63999999996 379625.60000000003 True False 539605.7519153549 672466.1482733941 657290.4645005057 348323.62044645107 423060.38731717254 350707.1866202051 569307.1695395898 490971.73828014545 502162.3299743285 366335.02329303895 1.472984338392655 1.8356589065072124 1.7942332092411637 0.9508335220458018 1.1548455932884085 0.9573400420949302 1.5540615375019418 1.3402260419075656 1.3707734670311293 1.0 18.482804110279233 -5.748739467374641 24.999971473996972 1.2079464018228214 1.7144289790531648 0.5663017385764602 0.204484588536668 175.52968562132241 345529.8674009712 0.05789913746535629 0.09944128263258005 1.7834483346511478e-06 5.748739467374641 0.5064825772303434 WLDES(ph)DAEMELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 15 WLDESDAEMELR 12 0 H3BPZ1;H3BS72;Q9P035 H3BPZ1 HACD3 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 1 WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR 187.78 5.714e-05 39553820.0 572269.0 643813.9 661855.2 465245.3 836295.8 432697.7 536200.1 389402.6 408023.6 407200.2 True False 669142.8388720409 707727.4891741632 677636.338067824 439179.11418661417 672429.6413896306 410006.2708912332 485407.34477545094 379181.1943561599 413990.1732451863 481022.37286498974 1.3910846493201503 1.4712984865109457 1.4087418305136061 0.9130118243167041 1.3979176007648273 0.8523642433702582 1.0091159417062956 0.7882818258488489 0.8606463994168154 1.0 18.87574447128189 -6.079225029908663 0.6634662695845388 0.8696677901985715 1.5073322477142663 0.6167529904677234 0.16081759623075026 0.6011236920082855 0.5273141681870979 0.09604219321580379 0.2295358398439987 8.332493241800234e-07 6.079225029908663 0.6376644575156948 WLDES(ph)DAEMELR ddPTM_PC-9_Lapatinib_30min_R1 22 WLDESDAEMELR 12 0 H3BPZ1;H3BS72;Q9P035 H3BPZ1 HACD3 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 1 WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR 167.73 6.6438e-18 32517280.0 417705.89999999997 575512.6 284497.39999999997 198960.30000000002 260114.90000000005 274175.29999999993 293600.7 262709.3 358105.5 147652.2 True False 411749.33726811985 574180.0359340878 261107.1219637225 213592.50417410405 244815.4529875694 262449.4615528406 308801.90764674183 274915.7331454512 317771.88757190836 173173.68603581015 2.377666877073779 3.315630966100442 1.5077759672432496 1.2334004609103013 1.413698920383 1.5155273734750285 1.783191861971948 1.5875144742752778 1.8349894539185192 1.0 17.401860201789198 -5.274273226781067 24.82970822731963 1.5057723839672696 2.846648890027373 0.7534046164707744 0.3115260162890594 274.5226059540284 531120.4820466762 0.07830003387969334 0.1646942155082854 5.317736003907615e-06 5.274273226781067 1.3408765060601036 WLDVIER ddPTM_PC-9_Lapatinib_30min_R1 1 WLDVIER 7 0 B5MD46;Q9BXI6;Q9BXI6-2;F8W9Y7;H7C471;H0Y5R9;H0Y2U5;F8WCD1;H7C1Q1 B5MD46 TBC1D10A TBC1 domain family member 10A 0 76.035 0.026728 7129600.0 6616.7 8728.5 8232.5 5733.7 6252.6 6570.7 5199.0 6728.7 5876.9 5254.5 False True 6522.3446446458265 8708.289694527439 7555.65562836899 6155.3754250624925 5884.834361084572 6289.68647804981 5468.178781097629 7041.339966327024 5214.981635499446 6162.733323818851 1.0583525688896978 1.4130563886108878 1.2260234592930574 0.9988060656903779 0.954906540956396 1.0206001375623843 0.8872976476141226 1.1425676881250684 0.8462124452706136 1.0 12.589354648261212 -5.753769281751252 4.831594415060479 0.980045117557403 1.254860119241123 0.5305270364234246 0.10925003744574113 0.12738827561928434 7.778421847663015 0.028465516087471106 0.04729713359462822 1.7629123420483221e-06 5.753769281751252 0.2748150016837201 WLEASEEER ddPTM_PC-9_AZD4547_30min_R2 2 WLEASEEER 9 0 Q14137;Q14137-2 Q14137 BOP1 Ribosome biogenesis protein BOP1 0 ; 112.41 0.0021958000000000004 0.0 8868.400000000001 10865.7 15701.2 13556.3 14484.6 15307.800000000001 12091.0 17014.199999999997 12320.0 11595.599999999999 False True 11688.366725820732 14377.825034655561 15492.991829018178 10431.104477747163 12473.663312395456 14350.600846097403 13167.075576629328 14385.046337420714 12971.210048221508 11189.64157342595 1.0445702526861267 1.2849227511273609 1.3845833869971462 0.9322107780931768 1.1147509266086684 1.282489769840202 1.1767200486474514 1.2855681071664946 1.159215866129847 1.0 13.44987620419953 -8.557672851551777 19.796269524294964 0.9999999900574648 1.191809674177041 0.16593114324288183 0.12573068616585598 1414.6708462181484 804884.9157543558 0.1232464521862605 0.03182209711177523 2.7690267322062748e-09 8.557672851551777 0.19180968411957622 WLEASEEER ddPTM_PC-9_Lapatinib_30min_R1 1 WLEASEEER 9 0 Q14137;Q14137-2 Q14137 BOP1 Ribosome biogenesis protein BOP1 0 121.09 0.007545100000000001 1425700.0 6770.4 6456.1 12521.0 6853.4 10018.0 9811.4 7352.3 8414.4 9136.5 6905.5 False True 6673.852854460702 6441.151297111604 11491.57171245771 7357.4218982721995 9428.760936145798 9391.789293490485 7732.966118919807 8805.363742277425 8107.451158389751 8099.106473999633 0.8240233507098111 0.7952915939294635 1.418869075168826 0.9084239010675504 1.1641729820955835 1.159608078204765 0.9547925001041488 1.087201874743229 1.0010303216060819 1.0 12.983547037519156 WLHNEDQMAVEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 WLHNEDQMAVEK 12 0 P37837 P37837 TALDO1 Transaldolase 0 ; 73.082 0.015947 12587800.0 110695.0 115875.0 127355.0 126368.0 143592.0 128647.0 127229.0 123187.0 125775.0 110478.0 False True 129433.47717409175 127378.30420880369 130391.62619652711 119288.01065058378 115456.17838379684 121900.52484989975 115176.94806180726 119953.47177741528 127614.22143207747 130506.7868566332 0.9917758324421815 0.9760281995811737 0.9991175887256147 0.9140368368859338 0.8846756644972797 0.9340550617019806 0.8825360798157847 0.9191358906812168 0.9778359003832242 1.0 16.993765308893344 -5.76265648641003 24.99999734145318 0.9232178704011453 0.98767931440676 0.3541139878022108 0.035384883672438666 30.91627764244078 635058.7662190096 0.009593701437475684 0.01517146722630484 1.7272035167427767e-06 5.76265648641003 0.06446144400561471 WLHNEDQMAVEK ddPTM_PC-9_Lapatinib_30min_R1 2 WLHNEDQMAVEK 12 0 P37837 P37837 TALDO1 Transaldolase 0 ; 110.8 0.00077983 13344200.0 143744.0 116387.0 138450.0 126579.0 130482.0 129892.0 132535.0 109172.0 121905.0 101353.0 False True 141694.18420057851 116117.5130522958 127067.17543245484 135888.04191516538 122807.30529748206 124336.8219530411 139397.01380126446 114244.52967198029 108174.7751834402 118871.73100561672 1.1919922676475825 0.9768303369520986 1.0689435945578254 1.1431485077704862 1.0331077393975139 1.0459746897028541 1.1726674847081844 0.9610739972027681 0.9100126183771052 1.0 16.8590461416902 -7.87245973772422 8.41232314931479 0.9489594684976005 1.0831627507841768 0.4618120493757544 0.06557648907487318 0.22031669358431974 15.429318763073386 0.034655363490122645 0.01659667548318698 1.3413442820696115e-08 7.87245973772422 0.1342032822865763 WLIS(ph)PVK ddPTM_PC-9_AZD4547_30min_R2 1 WLISPVK 7 0 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3 C9JWC4 HJURP Holliday junction recognition protein 1 WLIS(1)PVK 92.439 0.014584999999999999 55905000.0 56477.0 49858.0 59827.0 75767.0 73794.0 60916.0 60566.0 70314.0 54950.0 62775.0 True False 74435.5112054236 65973.62347367006 59033.65488973264 58300.088738481 63548.97687715986 57106.91289021735 65956.25666811118 59448.58695497884 57854.54481735159 60577.266357222914 1.228769729661931 1.08908221583696 0.9745183043026797 0.9624087094766963 1.0490565305871156 0.9427119499493265 1.0887955273380687 0.9813679376750302 0.955053740394697 1.0 15.88648885530799 -4.880271429718122 2.5106297514253284 0.9962009309347812 1.2539202555660078 0.7438364962170112 0.04261342657709669 0.19829394618843502 1.8906330601468164 0.010937482476379327 0.10131661826164202 1.3174330986575651e-05 4.880271429718122 0.2577193246312266 WLIS(ph)PVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WLISPVK 7 0 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3 C9JWC4 HJURP Holliday junction recognition protein 1 WLIS(1)PVK 82.426 0.022498 46910000.0 30033.0 30520.0 29492.0 30389.0 33878.0 36221.0 36416.0 31557.0 31125.0 24342.0 True False 35116.99372121143 33549.823900346775 30195.201129032826 28686.402852467316 27239.849095257872 34321.50699657373 32966.41285099138 30728.66218740533 31580.144242285114 28755.011908834036 1.2212477543931353 1.166747000721627 1.0500848069465185 0.9976140139818325 0.94730787041995 1.1935834735658575 1.146457979412748 1.0686367400865153 1.0982483451026896 1.0 14.811525814766227 -5.101857837833363 3.525342638992927 1.066592081955545 1.2129543693538507 0.3762589153188197 0.0689127488324828 0.27858551588344865 6.216673512972699 0.019563060998076746 0.0675418751340317 7.909374914918745e-06 5.101857837833363 0.1463622873983057 WLIS(ph)PVK ddPTM_PC-9_Lapatinib_30min_R1 2 WLISPVK 7 0 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3 C9JWC4 HJURP Holliday junction recognition protein 1 WLIS(1)PVK;WLIS(1)PVK 90.65700000000001 0.015782 96088000.0 132628.0 101176.0 103517.0 99926.0 112919.0 95140.0 90165.0 88420.0 102485.0 84603.0 True False 130736.70039900328 100941.73318823503 95006.23184717579 107274.8913833642 106277.3264272956 91071.08398217225 94833.30251926662 92528.31599307958 90942.06008510618 99226.51582358842 1.3175581074663127 1.0172858771711388 0.9574681833642559 1.081111137410939 1.0710577263061678 0.9178099545900065 0.9557254100090309 0.9324958679148088 0.9165096580312171 1.0 16.598438076124218 -4.761210806989384 4.028282695417511 0.9807077101188966 1.3544916837724303 0.7712950084198679 0.05495130989261073 0.1266216963740888 3.870691556056903 0.015265932416025281 0.1425973420316786 1.732962611726978e-05 4.761210806989384 0.3737839736535338 WLNSGRGDEASEEGQNGS(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 2 WLNSGRGDEASEEGQNGSSPK 21 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5 P35611 ADD1 Alpha-adducin 1 WLNSGRGDEASEEGQNGS(0.752)S(0.248)PK;WLNSGRGDEASEEGQNGS(0.5)S(0.5)PK 106.74 3.3662e-05 35281000.0 36459.0 24884.0 30271.0 65060.0 53652.0 36825.0 34835.0 34826.0 34678.0 45822.0 True False 48052.20360568967 32927.266366858 29869.586761279963 50061.42216697994 46203.34590093207 34522.326928594346 37935.2475156631 29444.441921866095 36511.008283459865 44217.78572713134 1.0867166416296958 0.7446611318362408 0.6755106858042521 1.1321557907921886 1.0449041068237486 0.7807339594441064 0.857918298979558 0.6658958931948382 0.8257086528206066 1.0 15.432339161364133 -6.803034126692684 24.99918353083055 0.8071614492117689 0.922454408974151 0.10423272470779832 0.15469445338564625 355.51468251919636 213668.1929445992 0.056994068365405846 0.05026451033357497 1.5738591863598794e-07 6.803034126692684 0.11529295976238207 WLNSGRGDEASEEGQNGS(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 WLNSGRGDEASEEGQNGSSPK 21 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5 P35611 ADD1 Alpha-adducin 1 WLNSGRGDEASEEGQNGS(0.5)S(0.5)PK;WLNSGRGDEASEEGQNGS(0.596)S(0.404)PK 109.5 2.1038e-05 19258500.0 21650.3 8403.1 11314.6 23619.0 22636.1 28876.0 27522.0 25840.0 27529.0 26140.3 True False 25315.26817708336 9237.304233846797 11584.382974859454 22295.704003831164 18200.718699603476 27361.69172670723 24914.916917975203 25161.727379743126 27931.55954524874 30879.32946349907 0.8198127555524574 0.29914199544927805 0.37515008182262444 0.7220268183020558 0.589414310991359 0.8860843872613923 0.8068477311797166 0.8148404715032935 0.9045390567261267 1.0 14.91435380475299 -6.523858268524229 1.2061487708778829 0.8820597555627038 0.4956289582618015 0.5267557526113813 0.15065553911508126 0.3624933040765756 1.105519454573688 0.06765323712328151 0.07648272471031256 2.993241317892417e-07 6.523858268524229 -0.3864307973009023 WLNSGRGDEASEEGQNGSS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 1 WLNSGRGDEASEEGQNGSSPK 21 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5 P35611 ADD1 Alpha-adducin 1 WLNSGRGDEASEEGQNGS(0.148)S(0.852)PK 94.845 0.00017273 8854100.0 14671.0 8789.7 16168.0 24235.0 22547.0 13734.0 12577.0 11115.0 9852.3 14607.0 True False 19336.072824242925 11630.798633048209 15953.60175601647 18647.99517701752 19416.738239549628 12875.210808888387 13696.328635122583 9397.432147290572 10373.072464130903 14095.613376024776 1.3717794542472088 0.8251360421697598 1.1318132336938203 1.3229644343633808 1.3775021860755312 0.9134196906101176 0.9716731205481746 0.6666919627119358 0.7359078450445057 1.0 13.78295863825205 -6.9197051914993875 6.046991132920754 0.8326611593937594 1.1864992641384924 0.4971276573409983 0.17544200117338085 0.19301092868055944 11.343007221860054 0.06592573192483615 0.05798517277149706 1.203080834818954e-07 6.9197051914993875 0.353838104744733 WLNSGRGDEASEEGQNGSS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 WLNSGRGDEASEEGQNGSSPK 21 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5 P35611 ADD1 Alpha-adducin 1 WLNSGRGDEASEEGQNGS(0.069)S(0.931)PK;WLNSGRGDEASEEGQNGS(0.217)S(0.783)PK 135.76 3.3451e-05 18749600.0 42888.0 17656.6 25675.0 47589.0 48835.0 47584.0 48162.0 53111.0 49900.0 42798.0 True False 50148.091323388166 19409.430559595767 26287.189372979734 44922.74261561967 39266.13231498073 45088.61127315547 43599.746697315655 51716.89252575606 50629.69309847476 50556.9386112184 0.9919131320237908 0.38391229953328077 0.5199521587952064 0.8885574136732138 0.7766714795952403 0.8918382424198144 0.8623889795344735 1.022943515695396 1.0014390603793446 1.0 15.625621485783372 -6.574794595845697 0.8544015383416875 0.9944903830247688 0.6265041601673762 0.3982742155742496 0.16045147034588564 0.5916486067710971 0.9523488522451148 0.09550274529279805 0.10992729578597556 2.6619837754077726e-07 6.574794595845697 -0.3679862228573926 WLNSGRGDEASEEGQNGSS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 3 WLNSGRGDEASEEGQNGSSPK 21 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5 P35611 ADD1 Alpha-adducin 1 WLNSGRGDEASEEGQNGS(0.182)S(0.818)PK;WLNSGRGDEASEEGQNGS(0.062)S(0.938)PK;WLNSGRGDEASEEGQNGS(0.217)S(0.783)PK 138.66 5.5003e-05 56651000.0 275504.0 101287.0 83747.0 83613.0 76229.0 87004.0 64659.0 49356.0 78187.0 62848.0 True False 271575.2624387535 101052.4761745545 76861.64493276861 89762.1789447915 71745.36009198023 83283.0417362298 68006.72664108318 51649.2599429365 69380.75671438943 73711.19306030394 3.6843151109570944 1.3709244414465298 1.0427404813525032 1.2177550683700924 0.9733306043938884 1.129856108394488 0.9226105808034627 0.7006976525353711 0.9412513057227044 1.0 16.169596089052686 -4.738843373642689 3.0699484990931514 0.9948442100624137 4.2752972459574945 0.9744444899149642 0.1300570108773348 0.07005720468420061 0.8830363075668112 0.037962279966324154 0.5961312833575781 1.8245536007523725e-05 4.738843373642689 3.2804530358950807 up WLPS(ph)SPSGVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WLPSSPSGVAK 11 0 Q8IWI9-3;Q8IWI9;H3BP52;H3BTF4 Q8IWI9-3 MGA MAX gene-associated protein 1 WLPS(0.795)S(0.205)PSGVAK 140.91 0.0001258 42967000.0 168600.0 170660.0 172940.0 208550.0 223150.0 204760.0 212740.0 209260.0 192760.0 150620.0 True False 197140.64999820996 187601.99694735196 177063.5454786021 196865.6196282223 179425.3593956782 194022.02514062097 192587.7270957796 203767.14672929773 195578.75033390732 177926.21369273565 1.1079910368837282 1.0543808753853754 0.9951515395273721 1.1064452816839767 1.0084256595575707 1.0904634067899714 1.0824022109994609 1.145233984921341 1.0992126807782028 1.0 17.440919551531515 -6.951782367633524 24.992859930586203 1.092760614624005 1.0536024438531448 0.06845584415694272 0.047660730664004114 231.4010588233935 119942.50352298854 0.01619372615818811 0.014281519196642167 1.1174230672443232e-07 6.951782367633524 -0.039158170770860146 WLPSS(ph)PSGVAK ddPTM_PC-9_AZD4547_30min_R2 1 WLPSSPSGVAK 11 0 Q8IWI9-3;Q8IWI9;H3BP52;H3BTF4 Q8IWI9-3 MGA MAX gene-associated protein 1 WLPS(0.024)S(0.973)PS(0.004)GVAK 184.98 0.0011784 66687000.0 426890.0 398660.0 611540.0 766270.0 628730.0 567630.0 497380.0 589870.0 462340.0 563440.0 True False 562632.1401363943 527519.0487787975 603430.5800268623 589618.2902534854 541441.6921697793 532136.0063673594 541645.8564472654 498719.14536413003 486778.34851418243 543714.1370977878 1.0347940245578056 0.9702139649974236 1.1098305871681509 1.0844269994536517 0.995820515280073 0.9787054815380936 0.9961960145793478 0.9172451318374211 0.8952835972087932 1.0 19.052488814538464 -6.981076473230166 1.2846208762356213 0.9379769011395576 1.0456344959878197 0.4695512685802724 0.04580729369008708 0.40368550283811555 1.3650074278691493 0.026311051144410194 0.019427709442332807 1.0445362746866427e-07 6.981076473230166 0.1076575948482621 WLPSS(ph)PSGVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 WLPSSPSGVAK 11 0 Q8IWI9-3;Q8IWI9;H3BP52;H3BTF4 Q8IWI9-3 MGA MAX gene-associated protein 1 WLPS(0.152)S(0.835)PS(0.013)GVAK;WLPS(0.264)S(0.734)PS(0.003)GVAK;WLPS(0.276)S(0.716)PS(0.008)GVAK 164.81 0.00020273 53962600.0 186701.0 173729.0 189976.0 210276.0 228073.0 213184.0 233944.0 234664.0 199996.0 194780.0 True False 218305.79178716423 190975.66698503803 194505.7483279916 198494.9174439903 183383.73288573002 202004.25575101646 211783.1307121134 228504.31864706086 202920.56314474056 230092.07212236893 0.9487758086296147 0.8299967279336431 0.8453387660594773 0.8626760392614725 0.7970015272329843 0.8779279263632576 0.9204277607595347 0.9930994863896759 0.8819102773641943 1.0 17.81185175045087 -7.3110458238936715 2.91450222588458 0.9531279220324193 0.8541611430709113 0.4689309048269835 0.04721951815678148 0.23421995060493453 3.95497370268704 0.021008584400492022 0.013742816352511848 4.886008026839174e-08 7.3110458238936715 -0.09896677896150796 WLPSS(ph)PSGVAK ddPTM_PC-9_Lapatinib_30min_R1 2 WLPSSPSGVAK 11 0 Q8IWI9-3;Q8IWI9;H3BP52;H3BTF4 Q8IWI9-3 MGA MAX gene-associated protein 1 WLPS(0.232)S(0.739)PS(0.029)GVAK;WLPS(0.035)S(0.964)PS(0.001)GVAK 182.23 0.0015364 110787000.0 797880.0 693940.0 675590.0 629040.0 699190.0 695520.0 653020.0 662880.0 737080.0 624800.0 True False 786502.0848867262 692333.224565545 620045.5980528151 675301.7000159257 658065.0188604291 665774.2309363097 686830.1803486011 693679.8247624132 654062.2886035041 732795.8475063328 1.073289494697811 0.9447832256712697 0.8461368881425828 0.9215413847034521 0.8980195795319952 0.9085398521319488 0.9372735703755002 0.946620845523307 0.8925573075082848 1.0 19.4830518026547 -4.7887961907010945 4.018319317883388 0.9154456547726266 1.0859548739426066 0.5941063415782684 0.03795764940135574 0.14105614588195572 4.279838348547027 0.009109204867141984 0.06862936255798527 1.6263117857135015e-05 4.7887961907010945 0.17050921916997996 WLREAEEES(ph)DHN ddPTM_PC-9_Lapatinib_30min_R1 2 WLREAEEESDHN 12 1 Q04637-9;Q04637;Q04637-8;Q04637-3;E7EUU4;Q04637-6;Q04637-7;Q04637-4;Q04637-5;E9PGM1;E7EX73 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 WLREAEEES(1)DHN;WLREAEEES(1)DHN 62.035 0.025169999999999998 12627800.0 294360.0 20654.4 31007.0 29267.0 17535.9 20510.6 11269.0 10965.8 29950.0 13521.8 True False 290162.37242098723 20606.576005802563 28457.724150481303 31419.392811849928 16504.47283890588 19633.40945054386 11852.453680359527 11475.311100621053 26576.71561251826 15859.025113334044 18.296356197646904 1.2993595670945022 1.7944182537774311 1.9811679839912069 1.0406990796066746 1.237995987157897 0.7473633212418682 0.7235823777700418 1.6758101726046788 1.0 13.953016467906181 -4.761438038451439 12.395757881241046 1.2809011717554966 18.31513745058525 0.9937336443021996 0.40543024824469875 0.004315198969844368 42.75835360556643 0.1100501542886843 0.6153682907586694 1.7320561285810294e-05 4.761438038451439 17.034236278829756 WLSTSIPEAQWHS(ph)SLAR ddPTM_PC-9_AZD4547_30min_R2 1 WLSTSIPEAQWHSSLAR 17 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 1 WLSTSIPEAQWHS(0.856)S(0.144)LAR 136.81 3.0431e-05 5378100.0 22019.0 23775.0 31012.0 50342.0 39660.0 31772.0 24987.0 30531.0 26916.0 25404.0 True False 29020.583976348236 31459.803804535008 30600.760617119162 38736.429676146734 34153.89358143158 29785.291817387628 27210.794593767034 25813.13548258466 28338.724809896907 24514.613692375817 1.1838075174471872 1.283308160565434 1.248266075130369 1.580136246984548 1.3932054573657684 1.2150014759013323 1.1099825979403357 1.0529692944177493 1.1559931217154122 1.0 14.581354406990512 -7.067662023485596 2.8597999019632168 1.0830184484750462 1.3420207748325195 0.5683351270547885 0.10559077308273317 0.22247592452799062 3.574981970393953 0.047134165445479624 0.036366680962584726 8.557324016240976e-08 7.067662023485596 0.2590023263574732 WLSTSIPEAQWHSS(ph)LAR ddPTM_PC-9_AZD4547_30min_R2 1 WLSTSIPEAQWHSSLAR 17 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 1 WLSTSIPEAQWHS(0.274)S(0.726)LAR 74.742 0.0053373000000000006 5177700.0 17320.0 16753.0 34208.0 49313.0 42126.0 36060.0 25989.0 36464.0 29475.0 30321.0 True False 22827.39972162004 22168.079627229206 33754.37956888984 37944.64972825519 36277.53204769004 33805.16249952783 28301.970652635802 30829.326659361534 31032.988325594888 29259.47101899412 0.7801713061319998 0.7576377444704501 1.1536223449486764 1.2968330734216962 1.2398560460693244 1.1553579515358574 0.9672755407732168 1.0536529057325856 1.060613443949464 1.0 14.836616066825835 -5.259722461253308 24.9628289204706 1.1248074850781973 0.7689044879211592 0.6703547793889624 0.09717178671537854 89.84035985689754 1306190.475067357 0.0283690281817458 0.0675151466098763 5.498921738078328e-06 5.259722461253308 -0.3559029971570381 WLSTSIPEAQWHSS(ph)LAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 WLSTSIPEAQWHSSLAR 17 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 1 WLSTSIPEAQWHS(0.242)S(0.758)LAR;WLSTSIPEAQWHS(0.25)S(0.75)LAR 160.05 1.673e-05 7619800.0 31225.0 34252.0 36739.0 40501.0 35692.0 31306.0 31190.0 26248.0 28603.0 25294.5 True False 36510.77577813831 37652.31219641802 37614.9970934334 38231.860276013635 28698.408817165822 29664.258248936694 28235.457403954908 25559.017812054863 29021.26476344034 29880.19261884819 1.2219056364150613 1.2601094202005658 1.2588605961564705 1.2795051478984536 0.9604492575815289 0.992773327378911 0.9449556689318062 0.8553833015096575 0.9712542731446101 1.0 14.86690182785603 -6.265715635298114 23.803758752375973 0.9483779623940725 1.255722329222671 0.9325728316214105 0.03962679872909883 44.603981473195674 248287.57171347731 0.012698849627315873 0.014924242136861526 5.423558946622756e-07 6.265715635298114 0.30734436682859845 WLTS(ph)PVR ddPTM_PC-9_AZD4547_30min_R2 2 WLTSPVR 7 0 E7EPJ7;O75962-4;O75962;O75962-5;O75962-2;E7EWP2;C9J1B4;A0A1W2PRD7;H7BXZ5;O60229-5;O60229-6;O60229-4;O60229 E7EPJ7 TRIO;KALRN Triple functional domain protein;Kalirin 1 WLT(0.224)S(0.776)PVR;WLT(0.223)S(0.777)PVR 107.01 0.0099709 23733000.0 173664.0 190274.0 240220.0 349330.0 326130.0 255650.0 205907.0 274530.0 206454.0 266460.0 True False 228885.53956440062 251776.34948913121 237034.5258430402 268797.36559469905 280852.47891357186 239664.16508608728 224232.3241052858 232107.696571811 217366.73695580542 257131.31650411236 0.8901503818215002 0.9791741936074305 0.9218423063580793 1.0453700049033121 1.0922531052691908 0.9320691401751302 0.8720537317425495 0.9026815548081979 0.8453530278266553 1.0 17.9721458038374 -6.991607686878642 24.985167425499835 0.8976477991192813 0.9878539406472913 0.2566934489742 0.06486698205533625 249.35796714270748 742371.5317702855 0.0235290223949399 0.02071807837476645 1.0195119323555364e-07 6.991607686878642 0.09020614152800999 WLTS(ph)PVR ddPTM_PC-9_Lapatinib_30min_R1 2 WLTSPVR 7 0 E7EPJ7;O75962-4;O75962;O75962-5;O75962-2;E7EWP2;C9J1B4;A0A1W2PRD7;H7BXZ5;O60229-5;O60229-6;O60229-4;O60229 E7EPJ7 TRIO;KALRN Triple functional domain protein;Kalirin 1 WLT(0.048)S(0.952)PVR;WLT(0.224)S(0.776)PVR 80.455 0.025381 20821500.0 256960.0 226430.0 248870.0 226290.0 232340.0 207570.0 200776.0 183721.0 219590.0 163839.0 True False 253295.70327930702 225905.71524681756 228408.8692659814 242932.12148131116 218674.2179980151 198692.71496930296 211171.19887548703 192257.3483664847 194857.46181478715 192158.35284825554 1.3181612952278514 1.175622666922066 1.18864918376123 1.2642287877704221 1.137989656742628 1.034005090198746 1.0989436355246323 1.000515176763132 1.0140462744737568 1.0 17.55193616408676 -6.574219449850016 2.623376919993292 1.0319196465596534 1.229123017903864 0.8185349044576679 0.045848164163659534 0.12124368390303086 1.6933034165006604 0.016391769157364077 0.016974526012703404 2.6655114360363616e-07 6.574219449850016 0.1972033713442105 WLTS(ph)PVRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WLTSPVRR 8 1 E7EPJ7;O75962-4;O75962;O75962-5;O75962-2;E7EWP2;C9J1B4;A0A1W2PRD7;H7BXZ5;O60229-5;O60229-6;O60229-4;O60229 E7EPJ7 TRIO;KALRN Triple functional domain protein;Kalirin 1 WLT(0.025)S(0.975)PVRR 56.916000000000004 0.038342 8254200.0 8285.7 6939.5 10752.0 10104.0 15646.0 10592.0 12383.0 12174.0 12571.0 8579.9 True False 9688.305359965432 7628.40769844222 11008.368457187067 9537.905637609983 12580.278615750776 10036.536873849665 11209.992594843654 11854.445399419224 12754.827093004536 10135.367951548968 0.9558908375383439 0.752652270239127 1.086134071284968 0.9410517391381262 1.241225644287355 0.9902488909952009 1.1060271958977526 1.1696117453345671 1.2584473651057968 1.0 13.307110844500201 -5.65138484822326 1.2816998909925674 1.1265990427435701 0.8548291141757737 0.41299702163598695 0.11207479655498227 0.46167175548123135 1.4511070987857906 0.036477963433754194 0.10876202728785882 2.231593828928772e-06 5.65138484822326 -0.27176992856779647 WMDSVS(ph)S(ph)HSPLS(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 WMDSVSSHSPLSK 13 0 Q96JM4-2;Q96JM4 Q96JM4-2 LRRIQ1 Leucine-rich repeat and IQ domain-containing protein 1 3 WMDS(0.398)VS(0.677)S(0.92)HS(0.03)PLS(0.974)K 73.36 0.018613 8926700.0 2687.7 2152.0 20762.0 40960.0 20202.0 13317.0 4963.7 30433.0 10103.0 9830.2 True False 3542.332692367098 2847.591915346341 20486.682314350186 31517.304825691645 17397.30101190319 12484.28588480899 5405.459684038959 25730.2791307687 10637.023954316715 9486.047690080011 0.3734255622677794 0.300187391881257 2.159664697424412 3.322490657373641 1.8339883564043573 1.3160682185758326 0.569832649027444 2.712434089665817 1.1213335945422593 1.0 13.211591406091227 -5.253884623897217 24.167590101881075 1.8165089636378198 0.3368061162550579 0.34132646261339195 0.7839645941537972 406.57122159449835 1300603.6200344376 0.20918859065341788 0.529969912022685 5.573337923975463e-06 5.253884623897217 -1.4797028473827618 WMERY(ph)LRDKT(ph)VMIIVAIS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WMERYLRDKTVMIIVAISPK 20 3 O43734-3;O43734-2;O43734 O43734-3 TRAF3IP2 Adapter protein CIKS 3 WMERY(1)LRDKT(1)VMIIVAIS(1)PK 40.179 0.043701 0.0 2894.3 2742.3 3123.4 3016.0 3392.5 4791.8 2710.2 3129.8 3073.0 2723.8 True False 3384.247824969276 3014.537420770675 3197.8737015604643 2847.0232980039273 2727.7639782650185 4540.5095725182055 2453.470235851188 3047.646066297212 3117.9368114551676 3217.603378411064 1.0517914817209402 0.9368890650094145 0.9938682073176021 0.8848272963368969 0.8477626535847494 1.4111464461354546 0.762514812208699 0.9471789117160297 0.9690245952547717 1.0 11.651770786216078 -9.392067795071878 0.004558835413288449 0.8289033135575576 1.1225855478418734 0.0 0.16388970569103745 1304288.9324656026 1945.1421627298282 63602.324387239685 61698.001464273926 4.0544523891618994e-10 9.392067795071878 0.2936822342843157 WMPPESIFYNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WMPPESIFYNR 11 0 Q5T0B5;A0A087WSY1;O15146-3;O15146-2;O15146 Q5T0B5 MUSK Receptor protein-tyrosine kinase;Muscle, skeletal receptor tyrosine-protein kinase 0 60.167 0.04392 9705600.0 6547.1 9202.2 9743.3 9261.5 12160.0 11403.0 8710.1 10849.0 10466.0 9168.6 False True 7655.394718880679 10115.73360077887 9975.617223671014 8742.608181188123 9777.33529129038 10805.00660616576 7885.016272336887 10564.22524546568 10619.045450273288 10830.79460140234 0.7068174589784465 0.9339788974918899 0.9210420463868274 0.8071991486253608 0.9027348085822289 0.9976190116989901 0.7280182629736103 0.9753878301872564 0.9804493429224819 1.0 13.402851469720988 -1.5228787715525511 0.08441109720978827 1.0893626757175903 0.35706945088044495 0.2672292392894724 0.0891989297027311 278.6183515659959 1.7109710589958536 2.1038426946817874 23.69795105561812 0.029999998185179833 1.5228787715525511 -0.7322932248371453 WNS(ph)FQLSHQPR ddPTM_PC-9_AZD4547_30min_R2 2 WNSFQLSHQPR 11 0 H3BRG5;Q9Y3M8-5;Q9Y3M8-3;Q9Y3M8-4;Q9Y3M8-2;Q9Y3M8 H3BRG5 STARD13 StAR-related lipid transfer protein 13 1 WNS(1)FQLSHQPR;WNS(1)FQLSHQPR 110.25 0.0011106 10165700.0 41981.0 43337.0 45889.0 50385.0 54428.0 58848.0 52785.0 64354.0 50776.0 53900.0 True False 55330.08474095439 57344.83774877528 45280.48187666004 38769.5166904901 46871.61169566711 55168.22525713294 57482.76274190548 54409.56800780366 53459.915698741526 52012.97740588318 1.0637746097322245 1.1025101928175527 0.8705612355799952 0.7453816071314711 0.9011522514834052 1.0606627039753518 1.1051619347483002 1.0460767816312204 1.027818793790003 1.0 15.666584004788996 -6.76837596904442 24.97328206005258 1.054399983569878 0.9315884817565528 0.24894008031071801 0.09610530253491428 250.35884097842006 901342.628804053 0.038304690861308076 0.034511893188853 1.7046060713723348e-07 6.76837596904442 -0.12281150181332523 WNS(ph)FQLSHQPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 WNSFQLSHQPR 11 0 H3BRG5;Q9Y3M8-5;Q9Y3M8-3;Q9Y3M8-4;Q9Y3M8-2;Q9Y3M8 H3BRG5 STARD13 StAR-related lipid transfer protein 13 1 WNS(1)FQLSHQPR;WNS(0.991)FQLS(0.009)HQPR 115.1 0.00078926 10046700.0 69283.0 68589.0 58825.0 60193.0 80278.0 60728.0 64470.0 55426.0 56933.0 46710.0 True False 81011.2434983748 75398.06263109074 60227.6110950548 56820.58135833902 64548.10218044486 57543.31677446588 58362.93487762012 53971.12622870133 57765.53741834597 55178.153243843444 1.4681760576576328 1.3664477369855315 1.0915119037945467 1.0297659131003778 1.169812659281903 1.0428641299423396 1.0577181628334402 0.9781249109623511 1.0468914601593924 1.0 15.751809551526353 -5.202276069865158 2.6018818599703737 1.0499618928680847 1.4612831997031077 0.9053901775917476 0.04793201730674551 0.08413151001330034 1.0756051804758902 0.013595875868313423 0.049100116309053324 6.27659245087083e-06 5.202276069865158 0.411321306835023 WNS(ph)FQLSHQPR ddPTM_PC-9_Lapatinib_30min_R1 2 WNSFQLSHQPR 11 0 H3BRG5;Q9Y3M8-5;Q9Y3M8-3;Q9Y3M8-4;Q9Y3M8-2;Q9Y3M8 H3BRG5 STARD13 StAR-related lipid transfer protein 13 1 WNS(1)FQLSHQPR;WNS(1)FQLSHQPR 88.76799999999999 0.0054676 11244100.0 30403.0 44576.0 46863.0 35264.0 49071.0 42608.0 39801.0 39303.0 54201.0 46578.0 True False 29969.44764477265 44472.78701074129 43010.10503641129 37857.4321972555 46184.74025729791 40785.75516409916 41861.70103221134 41129.16086265567 48096.31261816697 54628.94523871627 0.5486001516927128 0.8140883338751126 0.7873134809479985 0.6929921863185714 0.8454261757293854 0.7465960579299954 0.766291584969929 0.7528822070960813 0.8804181081658605 1.0 15.737377947678464 -14.522878745259701 0.10225543765339042 1.7776662473521594 0.6038672327288905 0.569217208504633 0.07397031956981864 142.1659149258876 0.980454129487586 23.324151002717983 1.1474172514387224 3.000000000142549e-15 14.522878745259701 -1.1737990146232689 WNS(ph)IEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 WNSIEER 7 0 Q9UNE7;Q9UNE7-2;H3BTA3;H3BS86;H3BUD0 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 WNS(1)IEER;WNS(1)IEER 105.17 0.010243 3191900.0 13712.6 17208.7 17676.7 18341.5 22959.0 19585.2 21769.3 21060.0 17006.8 14772.8 True False 16033.87234380462 18917.066007663765 18098.179567258063 17313.885218945306 18460.348762560527 18558.11763422587 19707.154307916484 20507.197314914465 17255.49227629541 17450.991698579535 0.9187943367774185 1.0840109453036737 1.0370860223795308 0.9921433416505843 1.0578395246192887 1.0634420068938806 1.1292856387938455 1.1751307701661273 0.9887972313745332 1.0 14.091021403260584 -6.587492678523595 2.4131916022466227 1.0870319103916106 1.0157134588695544 0.1514381737049839 0.06515754313152759 0.4912412058121279 5.805414144734058 0.023202616359706583 0.02388612675858369 2.58527842265204e-07 6.587492678523595 -0.07131845152205618 WNS(ph)IEER ddPTM_PC-9_Lapatinib_30min_R1 2 WNSIEER 7 0 Q9UNE7;Q9UNE7-2;H3BTA3;H3BS86;H3BUD0 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 WNS(1)IEER;WNS(1)IEER 95.48299999999999 0.013112 3668900.0 18436.2 15857.300000000001 16157.8 15555.0 23528.0 18837.4 16367.400000000001 15915.099999999999 22111.9 22309.7 True False 18173.296407214995 15820.583396119613 14829.368054911696 16698.96658995885 22144.12929782776 18031.768314124158 17214.82388569673 16654.57364692901 19621.42497337035 26165.90191919334 0.6945411804774988 0.6046259534633057 0.5667440052595315 0.6381957190518146 0.846297191138842 0.6891323054642121 0.6579105867957575 0.6364991238735962 0.7498852909395624 1.0 14.675400367985038 -14.522878745263062 0.22823781543090016 2.7446780911272493 0.6361417477314038 0.6609828079812999 0.071266663885194 105.90108750631529 1.0573403062283078 85.20265493719523 0.13681104494590784 3.000000000119333e-15 14.522878745263062 -2.1085363433958455 WNSPAEEGSSDCEVFSK ddPTM_PC-9_Lapatinib_30min_R1 1 WNSPAEEGSSDCEVFSK 17 0 A0A087WYC1;P34932;A0A087WTS8 A0A087WYC1 HSPA4 Heat shock 70 kDa protein 4 0 167.69 5.9532999999999994e-24 0.0 9513.7 9767.1 9911.5 8989.3 9920.6 9257.2 9896.6 9066.0 8302.4 8900.6 False True 9378.032893401092 9744.484880038843 9096.614729496421 9650.40310942572 9337.089812650032 8861.29113558719 10408.9975235643 9487.239457060185 7367.296283852133 10439.056850695984 0.8983601706102259 0.9334641069024513 0.8714019723812443 0.9244516288636091 0.8944380652575445 0.8488593617532025 0.9971204939716675 0.9088215145056575 0.7057434775212423 1.0 13.349703752540659 WNSVS(ph)PASAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 WNSVSPASAGK 11 0 Q86UE4;E5RJU9;H0YB56;H0YBE0 Q86UE4 MTDH Protein LYRIC 1 WNS(0.005)VS(0.896)PAS(0.1)AGK;WNS(0.009)VS(0.903)PAS(0.088)AGK 92.65 0.0075315 11492600.0 71276.0 79111.0 71681.0 54579.0 93228.0 41438.0 52970.0 47397.0 37465.0 36568.0 True False 83341.61903483066 86964.6172536151 73390.14689170636 51521.115577505465 74960.6426427977 39264.91833257009 47952.298130410076 46152.8789712726 38012.854748183505 43197.48892787129 1.9293162890553606 2.013186863681444 1.6989447468636212 1.1926877431123948 1.7353009284396768 0.9089629815782213 1.1100714259219582 1.0684157833418524 0.8799783434554543 1.0 15.398659830442833 -5.750860276537927 0.5394018617060329 0.940535844574296 2.2498695804025504 0.7771263878233817 0.19721163097951203 0.7549845091372882 0.3400914612449585 0.13425326074353067 0.5568228764685896 1.7747603741168245e-06 5.750860276537927 1.3093337358282544 WPFSGKTS(ph)PPCSPANLSR ddPTM_PC-9_Lapatinib_30min_R1 2 WPFSGKTSPPCSPANLSR 18 1 P49585;C9JEJ2 P49585 PCYT1A Choline-phosphate cytidylyltransferase A 1 WPFS(0.114)GKT(0.35)S(0.523)PPCS(0.013)PANLSR;WPFS(0.015)GKT(0.156)S(0.599)PPCS(0.229)PANLS(0.001)R 65.416 0.007064399999999999 34974000.0 206523.0 78940.0 111803.0 83998.0 73777.0 94999.0 46535.0 48525.0 100850.0 56722.0 True False 203577.94414832006 78757.21928005923 102610.98891206071 90175.49312911363 69437.58191116275 90936.11422348516 48944.354602496285 50779.64864922186 89491.21100241953 66526.32212268584 3.06011121091119 1.183850493565803 1.542411870038879 1.3554859227421996 1.0437610211354844 1.3669193083571267 0.7357141209795812 0.763301607979704 1.3452000373233097 1.0 16.021637656738147 -2.993386274177714 1.3127042120814374 1.1032062810195267 199.99999999999986 0.8193310254621148 0.26633574130646803 62.09911592306151 1.3627665054643041 0.07927959445827197 36069.6867928975 0.0010153452134959893 2.993386274177714 198.89679371898032 up WPGS(ph)PTSR ddPTM_PC-9_AZD4547_30min_R2 2 WPGSPTSR 8 0 O43524;O43524-2 O43524 FOXO3 Forkhead box protein O3 1 WPGS(0.916)PT(0.084)SR;WPGS(0.996)PT(0.004)SR 116.37 0.0035930999999999997 53897000.0 340300.0 315600.0 477990.0 636070.0 540390.0 492990.0 394860.0 565360.0 358130.0 487000.0 True False 448508.32132028305 417611.5281056254 471651.5402868826 489433.888683538 465366.17631038284 462163.25736667274 430001.77505482227 477996.60268035915 377060.02066311485 469950.2782312632 0.9543739882617357 0.8886291751488615 1.0036200894741938 1.0414588762998602 0.9902455597257365 0.9834301175564822 0.9149941918817586 1.017121650569885 0.8023402434875526 1.0 18.842148599006194 -10.221690425178943 8.634827729065226 1.0000000000002325 0.9596512158207191 0.03473392928786012 0.06726293725062622 0.0 0.0 0.06401787798001124 0.01552661616506403 6.002187731687232e-11 10.221690425178943 -0.040348784179513375 WPGS(ph)PTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 WPGSPTSR 8 0 O43524;O43524-2 O43524 FOXO3 Forkhead box protein O3 1 WPGS(0.699)PT(0.301)S(0.001)R;WPGS(0.941)PT(0.058)SR 93.598 0.007104899999999999 32295000.0 209550.0 182890.0 206753.0 223860.0 256980.0 196608.0 220100.0 211390.0 181518.0 166793.0 True False 245022.67619884314 201046.11052209768 211682.77563511845 211317.84996391193 206626.61374636553 186297.53037139704 199250.53461399412 205841.2364862193 184172.3573516822 197031.2505673384 1.243572659125477 1.020376767356441 1.0743614275684286 1.0725093067999936 1.0486997019579276 0.9455227525327361 1.0112636144787461 1.044713647675245 0.934736783232965 1.0 17.588064944031814 -1.5228787452803376 0.8441599397883016 1.0078216363214387 73.63419771728866 0.6705097908362443 0.046841885684036876 404.5754230967796 1.152839003747159 0.01634926181118775 56404.0908692424 0.029999999999999995 1.5228787452803376 72.62637608096722 WPGS(ph)PTSR ddPTM_PC-9_Lapatinib_30min_R1 1 WPGSPTSR 8 0 O43524;O43524-2 O43524 FOXO3 Forkhead box protein O3 1 WPGS(0.5)PT(0.5)SR 81.95 0.040471 0.0 173880.0 118030.0 176080.0 140550.0 148110.0 160170.0 122540.0 133150.0 144210.0 137360.0 True False 171400.43931431367 117756.70878674134 161603.38208845598 150886.5158610551 139398.4609954637 153319.90247450623 128884.52160717512 139336.63508797265 127967.55120137746 161102.49297930507 1.0639217068871272 0.7309428091958089 1.0031091331976796 0.9365870947784631 0.8652781121976219 0.9516916817308434 0.8000156870553914 0.8648943446571716 0.7943238421382836 1.0 17.29761929362749 -7.25028037422436 24.531822624058726 0.8535496610275141 0.9177503962843129 0.07642616623541809 0.09785673480371933 1413.9896341533301 3108502.3272202723 0.03522708731023335 0.027020210083639553 5.61978402940707e-08 7.25028037422436 0.06420073525679881 WPQGAVPQLPPSAPATSEMT(ph)TTPERPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WPQGAVPQLPPSAPATSEMTTTPERPR 27 1 F8VPD4;P27708;H7BZB3 F8VPD4 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 WPQGAVPQLPPS(0.02)APAT(0.163)S(0.163)EMT(0.218)T(0.218)T(0.218)PERPR 49.593 0.013725999999999999 4671400.0 10932.0 11915.0 16200.0 12747.0 21015.0 12380.0 12620.0 10485.0 15772.0 12725.0 True False 12782.571683157983 13097.842456508262 16586.26943884213 12032.826916331596 16897.26160743976 11730.77100625556 11424.542239112237 10209.7798597758 16002.635662307486 15031.941768955432 0.8503606439959115 0.8713340337412996 1.1034016558723476 0.8004838697008707 1.1240904114155539 0.7803895987996985 0.7600177285616326 0.6792056553107094 1.064575416022218 1.0 13.875743762689218 WPS(ph)PTPGGR ddPTM_PC-9_Lapatinib_30min_R1 1 WPSPTPGGR 9 0 H7BZ55 H7BZ55 Putative ciliary rootlet coiled-coil protein-like 3 protein 1 WPS(1)PTPGGR 67.89699999999999 0.025227 1782100.0 18583.0 16456.0 22192.0 15704.0 16972.0 17832.0 13490.0 13374.0 21112.0 15594.0 True False 18318.003012295158 16417.897143053626 20367.459423597287 16858.92454700829 15973.740328235823 17069.366928422285 14188.446192923066 13995.404864187392 18734.14424078416 18289.4021223011 1.0015637957874621 0.8976727086685101 1.1136208437760968 0.9217865315811191 0.8733877806075636 0.9332927787512982 0.7757741941505265 0.7652193751660236 1.0243169304009543 1.0 14.15872029393135 -5.989148564282169 24.983552020776976 0.8811560739660266 0.9976376994803783 0.2084526627708102 0.0924146384730578 309.1294526981406 711709.9720437906 0.025756030035449 0.038162220224723604 1.025301129294292e-06 5.989148564282169 0.1164816255143517 WQELS(ph)PETSGK ddPTM_PC-9_AZD4547_30min_R2 1 WQELSPETSGK 11 0 Q9NWF9-3;Q9NWF9;Q9NWF9-1 Q9NWF9-3 RNF216 E3 ubiquitin-protein ligase RNF216 1 WQELS(0.998)PET(0.002)SGK 119.17 0.00099161 6402700.0 60647.0 54483.0 62425.0 61375.0 62649.0 63835.0 52266.0 69252.0 55503.0 61732.0 True False 79931.48446403525 72093.56427686548 61597.20371222962 47225.941984297475 53951.26775045656 59843.38735877311 56917.572747341714 58550.69465264658 58436.775268379744 59570.781469758454 1.3417900939341052 1.2102168630012737 1.0340170498434689 0.7927702276034783 0.905666610699833 1.0045761677501754 0.9554612402766 0.9828760544692581 0.980963717893236 1.0 15.862317264518962 -5.204207637631703 2.456858671624071 0.9452852005635715 1.323300491783774 0.8216503414648612 0.06153799719501314 0.12731304608291943 1.4335684582458053 0.017880456075936847 0.06718768812412781 6.2487386707897725e-06 5.204207637631703 0.3780152912202026 WQELS(ph)PETSGK ddPTM_PC-9_Lapatinib_30min_R1 2 WQELSPETSGK 11 0 Q9NWF9-3;Q9NWF9;Q9NWF9-1 Q9NWF9-3 RNF216 E3 ubiquitin-protein ligase RNF216 1 WQELS(0.928)PET(0.036)S(0.036)GK;WQELS(0.999)PET(0.001)SGK 134.06 5.7858e-05 9494900.0 107238.0 103920.0 118752.0 108198.0 124621.0 103875.0 95552.0 108894.0 111133.0 91316.0 True False 105708.76645495952 103679.37962482555 108988.66895597603 116155.24185794711 117291.03779431275 99432.5083944518 100499.21502047329 113953.61277709162 98616.03125762915 107099.8489290783 0.9870113498008763 0.9680627999156396 1.0176360662109665 1.0845509402619729 1.0951559592953588 0.9284094178349044 0.9383693443584971 1.0639941504730963 0.9207859044034026 1.0 16.70859691951636 -6.775544525504219 24.99949235234413 0.972315010445675 1.029305634641582 0.2439376656041864 0.05288740542286656 408.7281671876575 724412.1569948002 0.019871508884494567 0.017603711334758007 1.6767004253004848e-07 6.775544525504219 0.05699062419590706 WQHWHEECER ddPTM_PC-9_AZD4547_30min_R2 2 WQHWHEECER 10 0 J3QLV0;J3QLD4;J3QL54;J3KT10;Q9BW27-2;Q9BW27-3;Q9BW27 J3QLV0 NUP85 Nuclear pore complex protein Nup85 0 ; 98.04 0.0020664999999999998 7018700.0 14790.0 8937.3 21446.3 30245.0 22653.0 17825.699999999997 17940.5 17402.5 13333.3 17497.800000000003 False True 19492.912348889153 11826.10744657289 21161.908049236525 23272.482530591904 19508.021969242807 16711.056161060274 19537.1697446463 14713.343494667046 14038.071017528557 16885.20734791581 1.1544372507391933 0.7003827197912746 1.2532809111075915 1.3782763842378574 1.155332094376131 0.9896861682970668 1.157058325792951 0.8713747596640059 0.8313828032003004 1.0 14.043472275091059 -7.766289927229306 24.961134637125795 0.8885340159523774 1.1093199997683152 0.23960557380556202 0.17234304624683794 184.2229044717379 947995.0911325444 0.09624238691245124 0.04855892562404259 1.7128134821030832e-08 7.766289927229306 0.22078598381593784 WQRPS(ph)SPPPFLPAASEEAEPAEGLR ddPTM_PC-9_AZD4547_30min_R2 3 WQRPSSPPPFLPAASEEAEPAEGLR 25 1 H3BLU1;Q4KMQ1;Q4KMQ1-2;Q4KMQ1-4;Q4KMQ1-3 H3BLU1 TPRN Taperin 1 WQRPS(0.5)S(0.5)PPPFLPAASEEAEPAEGLR;WQRPS(0.5)S(0.5)PPPFLPAASEEAEPAEGLR;WQRPS(0.5)S(0.5)PPPFLPAASEEAEPAEGLR 92.565 1.9249e-06 65876000.0 52257.0 48886.0 61917.0 69290.0 60716.0 60534.0 57165.0 73811.0 61677.0 58386.0 True False 68873.63898687634 64687.443482166 61095.94012415086 53316.26101982844 52286.63143444781 56748.79941060506 62252.5742567212 62405.20595804457 64937.1203039089 56341.92391131532 1.2224225621987366 1.1481227297808803 1.0843779530908204 0.9462981971249436 0.9280235356667847 1.0072215407469964 1.1049067893867008 1.1076158147576416 1.152554186934099 1.0 15.781921207904174 -5.166675283115753 2.340933304094684 1.0367306138308707 1.213541502365684 0.4390849609713223 0.06835163139463714 0.35821287432816096 3.558257064270848 0.02141197623608124 0.09048652081891093 6.812785522843505e-06 5.166675283115753 0.1768108885348132 WQRPS(ph)SPPPFLPAASEEAEPAEGLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 WQRPSSPPPFLPAASEEAEPAEGLR 25 1 H3BLU1;Q4KMQ1;Q4KMQ1-2;Q4KMQ1-4;Q4KMQ1-3 H3BLU1 TPRN Taperin 1 WQRPS(0.5)S(0.5)PPPFLPAASEEAEPAEGLR;WQRPS(0.5)S(0.5)PPPFLPAASEEAEPAEGLR;WQRPS(0.5)S(0.5)PPPFLPAASEEAEPAEGLR;WQRPS(0.5)S(0.5)PPPFLPAASEEAEPAEGLR 108.96 1.8065000000000002e-07 64998000.0 42893.9 52673.9 54751.8 54570.5 55025.4 49447.7 59911.0 40390.6 48411.1 38290.0 True False 50154.99007685783 57903.01668232227 56057.29055935777 51513.09180494807 44243.567873139 46854.5755642991 54235.79636192182 39330.3895473782 49119.02075269684 45231.67389652677 1.1088466500619405 1.280143131885475 1.2393370779864565 1.13887210813358 0.9781545554637622 1.035879761414201 1.1990667532223798 0.8695320371594358 1.085943024462523 1.0 15.46504576657632 -6.033707890201774 4.133291932086632 1.0311302744165989 1.2146331711843152 0.46617888406607233 0.08801846532400871 0.18760013843195097 7.118709564127896 0.02580640559725616 0.03589097130419583 9.253203422337202e-07 6.033707890201774 0.18350289676771636 WQRPS(ph)SPPPFLPAASEEAEPAEGLR ddPTM_PC-9_Lapatinib_30min_R1 4 WQRPSSPPPFLPAASEEAEPAEGLR 25 1 H3BLU1;Q4KMQ1;Q4KMQ1-2;Q4KMQ1-4;Q4KMQ1-3 H3BLU1 TPRN Taperin 1 WQRPS(0.5)S(0.5)PPPFLPAASEEAEPAEGLR;WQRPS(0.5)S(0.5)PPPFLPAASEEAEPAEGLR;WQRPS(0.5)S(0.5)PPPFLPAASEEAEPAEGLR;WQRPS(0.499)S(0.499)PPPFLPAAS(0.001)EEAEPAEGLR 119.43 2.4266e-09 76023000.0 55816.4 64729.6 77139.9 66456.2 84203.0 75102.6 79424.0 71763.0 78623.0 59909.1 True False 55020.447900525825 64579.72258817477 70797.75519062504 71343.61063938448 79250.34508946743 71890.6368707114 83536.18609538325 75097.37096371152 69767.64980310597 70264.30811114208 0.7830497357704861 0.9190971109546032 1.0075920064371684 1.015360608497492 1.1278890694278452 1.0231458731081056 1.1888850590152842 1.0687840381908358 0.9929315705030426 1.0 16.100504414692676 -4.7089632028275625 0.9666048068462268 1.0730763483730479 0.5972245781233341 0.7015878442910919 0.057202236696007686 1.2018119194959835 0.8130881220029407 0.019069158978042497 0.6201685873576172 1.954505051277139e-05 4.7089632028275625 -0.4758517702497138 WQRPSS(ph)PPPFLPAASEEAEPAEGLR ddPTM_PC-9_AZD4547_30min_R2 1 WQRPSSPPPFLPAASEEAEPAEGLR 25 1 H3BLU1;Q4KMQ1;Q4KMQ1-2;Q4KMQ1-4;Q4KMQ1-3 H3BLU1 TPRN Taperin 1 WQRPS(0.182)S(0.818)PPPFLPAASEEAEPAEGLR 89.631 3.1077999999999997e-06 22303000.0 12706.0 12417.0 20812.0 17988.0 16123.0 22366.0 15505.0 21844.0 15973.0 16143.0 True False 16746.243698782 16430.552422330646 20536.019281680772 13841.144511829625 13884.599753238052 20967.450484316127 16884.914962834988 18468.51172518356 16817.300170474195 15577.83848354678 1.0750043220995829 1.0547389125702193 1.3182842602566969 0.8885150867656356 0.8913046420338022 1.3459794506446978 1.0839061517211603 1.185563179685673 1.079565704076116 1.0 13.927207444437695 -6.746825727870925 24.999987600380074 1.147157122359209 1.0525045194294786 0.09815504404417608 0.13973474175040076 619.7165570245825 1060164.326752494 0.04710403297694617 0.046910536525708785 1.791324526101347e-07 6.746825727870925 -0.09465260292973032 WQS(ph)PVTK ddPTM_PC-9_AZD4547_30min_R2 4 WQSPVTK 7 0 A9Z1X7;M0R088 A9Z1X7 SRRM1 1 WQS(1)PVTK;WQS(0.947)PVT(0.053)K;WQS(0.999)PVT(0.001)K;WQS(1)PVTK 101.38 0.011217 1594600000.0 343080.0 317036.0 437211.0 538550.0 487798.0 396681.0 374667.0 432218.0 380462.0 366641.0 True False 452172.30349268945 419511.68702311453 431413.29647140764 414395.61801455665 420075.6677063828 371876.4743614863 408011.63717384747 365428.63948156923 400572.4445914331 353805.0101868351 1.2780268522876745 1.1857143764063192 1.2193532710110286 1.1712542391520269 1.1873084202073678 1.051077468250402 1.153210456116456 1.032853207162318 1.1321842061532745 1.0 18.43259495242709 -1.5228787452803376 0.12762902987871488 0.9568789281224873 1.9723799389492542 0.7276644877984911 0.043619399721206105 41.907613496204476 0.3647009098588279 0.23242959231625557 7.631610420277225 0.029999999999999995 1.5228787452803376 1.015501010826767 WQS(ph)PVTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 WQSPVTK 7 0 A9Z1X7;M0R088 A9Z1X7 SRRM1 1 WQS(0.984)PVT(0.016)K;WQS(0.999)PVT(0.001)K;WQS(0.998)PVT(0.002)K;WQS(0.992)PVT(0.008)K;WQS(0.998)PVT(0.002)K 94.40899999999999 0.013456999999999998 989852000.0 1007380.0 1025640.0 1037220.0 1127370.0 1236350.0 1086450.0 1162650.0 1069800.0 957520.0 834800.0 True False 1177909.5373380594 1127458.7609813767 1061951.258478753 1064207.1138828543 994096.0927127344 1029474.6494140835 1052515.3751429354 1041718.8835467936 971521.918550131 986142.6317268346 1.1944616320617047 1.143301916688343 1.0768738966483682 1.0791614515430907 1.0080652237617722 1.0439409232428885 1.0673054193994995 1.0563572144960809 0.9851738351975503 1.0 19.911436801773355 -1.522878966925913 0.4284306739605786 1.022020510315976 4.613070068520805 0.8328331512783895 0.025068568938452336 32.45159426749065 0.4091281620877495 0.01720956837481505 100.4792415317193 0.029999984689269964 1.522878966925913 3.5910495582048285 WQS(ph)PVTK ddPTM_PC-9_Lapatinib_30min_R1 2 WQSPVTK 7 0 A9Z1X7;M0R088 A9Z1X7 SRRM1 1 WQS(0.824)PVT(0.176)K;WQS(1)PVTK 94.40899999999999 0.013456999999999998 837836000.0 1186240.0 919310.0 1028200.0 997560.0 974170.0 932230.0 922370.0 935530.0 1012990.0 782320.0 True False 1169324.0000702285 917181.3941772364 943665.3649667784 1070923.8901626063 916871.2358919102 892360.6960342708 970125.8054089274 978998.1391201761 898896.3989423984 917542.9696241246 1.2744078901822409 0.9996059307750608 1.028469942234264 1.1671648365430938 0.9992678994287433 0.9725546656412508 1.05730830873931 1.0669779743625816 0.9796777139610531 1.0 19.807416197092422 -4.756345413087789 24.999799666411384 1.0345257888388468 1.2744082607434801 0.6431438814582718 0.05450253954145508 105.51863180164743 517798.9146387552 0.013824932358521976 0.11285361026542898 1.752486119794183e-05 4.756345413087789 0.2398824719046333 WQSPVT(ph)K ddPTM_PC-9_Lapatinib_30min_R1 2 WQSPVTK 7 0 A9Z1X7;M0R088 A9Z1X7 SRRM1 1 WQS(0.481)PVT(0.519)K;WQS(0.301)PVT(0.699)K 125.16 0.011264 859511000.0 1379900.0 1248750.0 1476070.0 1129680.0 1343940.0 1308410.0 1152790.0 1143290.0 1213560.0 985340.0 True False 1360222.372957335 1245858.5960979715 1354713.222394974 1212760.4357020084 1264892.0914877006 1252452.3543526793 1212475.8255552105 1196411.427185342 1076876.0934466666 1155654.7061169792 1.177014523246054 1.0780543613101174 1.1722473981409507 1.0494141799300116 1.0945242422260892 1.0837600086975303 1.0491679038189108 1.0352672133403116 0.9318320496136686 1.0 20.140278973922236 -7.351702447606985 0.65675852486147 0.9695408946043135 1.1286884712145944 0.6587350949851285 0.04078150510827756 0.4544531921672543 0.38923272275834697 0.034845447362572 0.022589316162464044 4.4493600638677764e-08 7.351702447606985 0.1591475766102809 WREEER ddPTM_PC-9_AZD4547_30min_R2 1 WREEER 6 1 Q9NXE8;Q9NXE8-2 Q9NXE8 CWC25 Pre-mRNA-splicing factor CWC25 homolog 0 106.42 0.042762 857080.0 3385.9 2446.8 4055.6 4739.2 3666.8 2730.4 2262.4 3480.6 1853.2 2627.2 False True 4462.545768904923 3237.6802502181376 4001.820094118034 3646.6506599101053 3157.7281135752214 2559.6676563702376 2463.7492171504578 2942.7532462311824 1951.1563686172171 2535.2225276574427 1.760218568674654 1.2770793154831144 1.5784886929889086 1.438394705051642 1.2455427794312701 1.0096422023889882 0.9718078749588003 1.1607475139274264 0.7696193716060478 1.0 11.307896669152207 -6.481957477699807 1.7034026024657218 0.9813808418281873 1.5176279934853134 0.7595106062009017 0.14149866171318448 0.17702701891426434 1.0351030861708759 0.0514607606151097 0.058052908283523406 3.2964198624467323e-07 6.481957477699807 0.5362471516571261 WREEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 WREEER 6 1 Q9NXE8;Q9NXE8-2 Q9NXE8 CWC25 Pre-mRNA-splicing factor CWC25 homolog 0 ; 126.24 5.4494e-07 1023500.0 4734.3 6230.7 9015.599999999999 7609.700000000001 9113.599999999999 7194.0 9296.0 8634.3 6797.6 6542.9 False True 5535.723483312739 6849.242718738225 9230.566095853394 7183.353179980271 7327.8555025250025 6816.73397568679 8415.415582788224 8407.65877379706 6897.002040204248 7729.075976432098 0.7162206064725661 0.8861657900146529 1.1942651520051966 0.9293935267144645 0.9480894643641079 0.8819597577346543 1.0887996972017029 1.0877961090606603 0.8923449661039621 1.0 12.91608023258943 -4.925973760592464 4.220588024471174 1.0024991943594737 0.7276634946119265 0.4711842510469916 0.09368283451542501 0.18935970226398405 6.245051990894225 0.02380799037381945 0.11560022594720676 1.1858403926633918e-05 4.925973760592464 -0.2748356997475472 WREEQMER ddPTM_PC-9_Lapatinib_30min_R1 1 WREEQMER 8 1 P09496-2;F8WF69;P09496-4;P09496-3;P09496 P09496-2 CLTA Clathrin light chain A 0 106.68 0.004954500000000001 4109900.0 17575.0 12733.0 15701.0 10747.0 16072.0 10953.0 12914.0 11467.0 12854.0 9923.5 False True 17324.377277139723 12703.517520813193 14410.124387612703 11537.37023094104 15126.676558767744 10484.565722690066 13582.623731312717 11999.798682341607 11406.247161379284 11638.76375276742 1.4885066528668391 1.0914834075734718 1.2381146910200251 0.9912882910951543 1.2996806946245456 0.9008315612727414 1.1670160181817502 1.0310200410665042 0.9800222260433074 1.0 13.506650205624696 -1.568777037621614 0.9147952483307956 1.0645734722234519 199.99999899707598 0.5142748759788782 0.11900241313549295 707.3381358786585 1.5916053843649636 0.036355363423086554 293791.02554193157 0.026991247800654396 1.568777037621614 198.93542552485252 WREEQR ddPTM_PC-9_AZD4547_30min_R2 1 WREEQR 6 1 A0A0C4DG89;Q7L014;H0Y9Q6;D6RJA6;F8VW50;Q2TAC6-3;Q2TAC6-2;Q2TAC6;P09497-2;P09497 A0A0C4DG89;P09497-2 DDX46;CLTB;KIF19 Probable ATP-dependent RNA helicase DDX46;Kinesin-like protein;Kinesin-like protein KIF19;Clathrin light chain B 0 83.287 0.043607 0.0 11091.0 11938.0 13222.0 24091.0 17925.0 14984.0 11338.0 19133.0 12633.0 14916.0 False True 14617.707292868812 15796.72503968617 13046.667640898671 18537.1921522397 15436.423158022211 14047.048111284657 12347.060035383616 16176.434482601051 13300.754589219341 14393.795380077047 1.0155561411621628 1.0974676673221968 0.9064091364642447 1.2878599189966027 1.0724359177280165 0.9759099487219102 0.8578043323079062 1.1238477451882787 0.9240616694905486 1.0 13.813159434035406 -6.7513128215402824 7.3856444964886 0.9764976526677553 1.0797584553222581 0.17475325218839843 0.10813221076808989 0.2568445881632768 77.14945401180692 0.03641938664650263 0.03484712742695624 1.772911995513712e-07 6.7513128215402824 0.10326080265450277 WRPEDAEEAEHR ddPTM_PC-9_AZD4547_30min_R2 1 WRPEDAEEAEHR 12 1 E7EUV9;F8W8D3;Q14493;H0YAE8 E7EUV9 SLBP Histone RNA hairpin-binding protein 0 132.14 4.3169e-05 3915000.0 44860.0 36230.0 58236.0 78948.0 66202.0 56026.0 52032.0 62448.0 52759.0 54494.0 False True 59124.54685403434 47940.63898373513 57463.75258927355 60747.758334441016 57010.99502970077 52522.68536324309 56662.74720065974 52798.096512280885 55547.733030366784 52586.18164668268 1.1243361849559983 0.9116584905487123 1.0927538526254372 1.155203827929446 1.0841440326043756 0.9987925291121874 1.077521611691961 1.0040298583955387 1.0563180533544392 1.0 15.682396124145425 -6.74433274433101 24.97898722169467 1.0307210933016846 1.0702169651699391 0.11208930769430969 0.06443249112919604 704.5812249718315 1028823.7239125499 0.02206074322440141 0.022007831074042458 1.8016368479735326e-07 6.74433274433101 0.03949587186825454 WRPEDAEEAEHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WRPEDAEEAEHR 12 1 E7EUV9;F8W8D3;Q14493;H0YAE8 E7EUV9 SLBP Histone RNA hairpin-binding protein 0 115.57 0.00032282 3042300.0 23058.0 20368.0 26969.0 28524.0 30097.0 27114.0 24216.0 30560.0 28317.0 22871.0 False True 26961.263983741002 22390.000432577428 27612.043240502073 26925.892756055728 24199.708903122257 25692.09410853096 21922.085171342478 29757.832380996508 28731.082554499197 27017.33125326362 0.9979247665508841 0.8287273166505954 1.0220122402787883 0.9966155614575424 0.8957105598725262 0.9509486287779599 0.8114082388760863 1.1014349308613465 1.0634315538115395 1.0 14.721597553182896 -7.786094119282953 24.999491895238137 1.0618249809856173 0.9309251957071398 0.40400396367829716 0.06990325208859544 227.88951948701379 231072.72172304595 0.0373144942451908 0.017937513166481418 1.6364618328199193e-08 7.786094119282953 -0.13089978527847745 WRPEDAEEAEHR ddPTM_PC-9_Lapatinib_30min_R1 1 WRPEDAEEAEHR 12 1 E7EUV9;F8W8D3;Q14493;H0YAE8 E7EUV9 SLBP Histone RNA hairpin-binding protein 0 126.34 0.00012001 3279600.0 21899.0 19255.0 21013.0 21834.0 26132.0 22839.0 20704.0 19633.0 22473.0 18845.0 False True 21586.716244215248 19210.41623052368 19285.392252525686 23439.74519608884 24594.967137488722 21862.229210309364 21775.951814549975 20545.220853790266 19941.85408881878 22102.33314061589 0.9766713815631921 0.8691578444821311 0.87255006653964 1.060509994441052 1.1127769625502701 0.9891367156227817 0.9852331731682142 0.9295498680198504 0.9022510864327282 1.0 14.431911049289711 -5.749151350768179 24.999958352943917 0.998127925849375 0.9024295597169633 0.30918465273539164 0.06220411712772811 298.3737807170442 607035.2451998282 0.01883863990165935 0.032325449859338905 1.7817577201952243e-06 5.749151350768179 -0.09569836613241178 WRPHS(ph)PDGPR ddPTM_PC-9_AZD4547_30min_R2 7 WRPHSPDGPR 10 1 Q6Y7W6;I1E4Y6;Q6Y7W6-3;C9IYH5;C9JH78 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 WRPHS(1)PDGPR;WRPHS(1)PDGPR;WRPHS(1)PDGPR;WRPHS(1)PDGPR;WRPHS(1)PDGPR;WRPHS(1)PDGPR;WRPHS(1)PDGPR 76.17 0.0099045 261709100.0 160389.8 139505.8 194369.0 302707.0 243579.7 208932.5 171617.40000000002 220978.9 173842.5 191153.8 True False 211390.42008491262 184598.32166539208 191791.54006155138 232922.57792652925 209762.86314667208 195867.91774632852 186891.01613304354 186831.68859495383 183031.4596435021 184461.56364468872 1.1459862743660487 1.0007413903362914 1.0397371477940072 1.2627160549022913 1.1371629894166946 1.0618359395652246 1.013170507938632 1.012848882463289 0.9922471436708555 1.0 17.492960706895538 -7.06788664726266 3.0089410976794744 1.0053924610445932 1.1140244129384553 0.3970086601462124 0.06521529533134178 0.3235550352794247 5.744715390784359 0.02933427542208592 0.022714528994052772 8.552899181209114e-08 7.06788664726266 0.1086319518938621 WRPHS(ph)PDGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 WRPHSPDGPR 10 1 Q6Y7W6;I1E4Y6;Q6Y7W6-3;C9IYH5;C9JH78 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 WRPHS(1)PDGPR;WRPHS(1)PDGPR;WRPHS(1)PDGPR;WRPHS(1)PDGPR;WRPHS(1)PDGPR;WRPHS(1)PDGPR 71.45100000000001 0.013963 193857000.0 273358.0 248527.7 303343.0 303097.0 377716.0 342683.0 339705.0 335447.0 297875.0 258384.9 True False 319632.11033339694 273199.88759365113 310575.84755473357 286115.4577437328 303705.26125699293 324712.1002210561 307525.68314878165 326641.8716854758 302230.85835086496 305228.0369962565 1.047191186887321 0.8950681276930068 1.0175207055390612 0.9373826223809246 0.9950110227282881 1.063834447898502 1.0075276379428844 1.0701568404395365 0.9901805264192415 1.0 18.219527962748415 -6.529839816198791 22.728661913499373 1.029534941373384 0.9710293967668604 0.22522089706902637 0.04538312336825104 71.0395184443707 231945.74061891055 0.013675118861664616 0.013718208994924926 2.9522979420973205e-07 6.529839816198791 -0.058505544606523685 WRPHS(ph)PDGPR ddPTM_PC-9_Lapatinib_30min_R1 4 WRPHSPDGPR 10 1 Q6Y7W6;I1E4Y6;Q6Y7W6-3;C9IYH5;C9JH78 Q6Y7W6 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 WRPHS(1)PDGPR;WRPHS(1)PDGPR;WRPHS(1)PDGPR;WRPHS(1)PDGPR 72.325 0.013002000000000001 155298100.0 79900.3 68057.0 74948.70000000001 53531.1 74372.5 74068.5 67467.09999999999 74477.7 80973.0 58821.2 True False 78760.90707007947 67899.41819790959 68786.70719634848 57467.9556685147 69998.05577196086 70900.76291710664 70960.2163189444 77938.20583621126 71852.96805650892 68988.36604567758 1.1416549134955802 0.9842154857378852 0.9970769151251446 0.8330093748048019 1.0146356521274147 1.0277205705982781 1.0285823594076897 1.1297296965202501 1.0415229722781763 1.0 16.074065470956988 -7.009403553977043 2.1259065671488906 1.061258529423544 0.9852501127228086 0.10055791454929996 0.07624775137914634 0.6304935077914747 5.71027622851218 0.03449330882601957 0.026796233613557208 9.785802490356747e-08 7.009403553977043 -0.07600841670073533 WRS(ph)IFNLGRSGHETK ddPTM_PC-9_AZD4547_30min_R2 1 WRSIFNLGRSGHETK 15 2 A0A0A0MRJ9;A0A0A0MRJ8;Q7Z6I6-2;Q7Z6I6-3;Q7Z6I6 A0A0A0MRJ9 ARHGAP30 Rho GTPase-activating protein 30 1 WRS(1)IFNLGRSGHETK 83.89399999999999 0.017723 7117500.0 0.0 2709.1 60101.0 84708.0 67620.0 42919.0 11961.0 63706.0 25093.0 30580.0 True False 0.0 3584.7635956620707 59304.02147070422 65179.87932555396 58232.130206162445 40235.2681452367 13025.505828472695 53861.701518245034 26419.364751625195 29509.40350782758 0.0 0.12147868711447136 2.0096652057020874 2.2087833564058497 1.9733414872556116 1.3634727701142455 0.4414018678831507 1.8252385719676723 0.8952863023685744 1.0 14.848887138509932 -5.245943396194456 23.572740023058593 1.4987073251697602 0.06073848835391451 0.5242324436706294 0.5341885438164249 308.98973143161 470035.3141674463 0.14513803424739735 0.3803738044402583 5.676185812001604e-06 5.245943396194456 -1.4379688368158456 WRS(ph)IFNLGRSGHETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WRSIFNLGRSGHETK 15 2 A0A0A0MRJ9;A0A0A0MRJ8;Q7Z6I6-2;Q7Z6I6-3;Q7Z6I6 A0A0A0MRJ9 ARHGAP30 Rho GTPase-activating protein 30 1 WRS(1)IFNLGRSGHETK 83.89399999999999 0.021929 0.0 4346.5 1094.0 41972.0 10134.0 29760.0 28697.0 9902.0 15878.0 27888.0 6592.9 True False 5082.2766027118705 1202.6050900058783 42972.77165969639 9566.22483487129 23928.741633947535 27192.07880181872 8964.010875728161 15461.219324131634 28295.809241087456 7788.140580632318 0.6525661099840138 0.15441491811235886 5.517719051780063 1.2283066459612635 3.072458873361113 3.491472517771501 1.1509821610077273 1.985226019491849 3.6331918958234986 1.0 12.927063210470502 WRS(ph)IFNLGRSGHETK ddPTM_PC-9_Lapatinib_30min_R1 1 WRSIFNLGRSGHETK 15 2 A0A0A0MRJ9;A0A0A0MRJ8;Q7Z6I6-2;Q7Z6I6-3;Q7Z6I6 A0A0A0MRJ9 ARHGAP30 Rho GTPase-activating protein 30 1 WRS(1)IFNLGRSGHETK 74.618 0.044456999999999997 3377000.0 7476.1 1525.7 56471.0 7401.9 18033.0 27407.0 9176.5 11247.0 51188.0 7948.7 True False 7369.489443051169 1522.1673353887284 51828.17236436382 7946.260418014563 16972.33439424208 26234.866498837437 9651.614269040663 11769.576679192134 45422.66840646359 9322.622204023011 0.7904953436674712 0.16327673717506908 5.55939855012019 0.8523632347329806 1.8205537050421254 2.8141080829722185 1.0352896489654682 1.2624749154924655 4.87230603283079 1.0 13.186520088109912 WRS(ph)ILYNLY(ph)DLLVNEIS(ph)HIGS(ph)RGK ddPTM_PC-9_Lapatinib_30min_R1 1 WRSILYNLYDLLVNEISHIGSRGK 24 2 E9PIN0;Q13315 E9PIN0 ATM Serine-protein kinase ATM 4 WRS(0.785)ILY(0.216)NLY(0.999)DLLVNEIS(1)HIGS(1)RGK 53.358999999999995 0.0058173 3447400.0 3904.5 4368.1 3968.4 2605.4 4147.8 5705.3 3964.2 4424.4 5416.3 4711.5 True False 3848.8211140023936 4357.985932825264 3642.13347046699 2797.009807359614 3903.834558888557 5461.297618703882 4169.446879020428 4629.973776066299 4806.259257832475 5525.876497320874 0.6965087105852671 0.7886506212974826 0.659105116126431 0.5061658197963158 0.7064643158024367 0.9883133691735055 0.7545313184328157 0.8378713817275979 0.8697731952863418 1.0 12.431987603111114 -6.609591857148993 7.256374911749786 0.8706374887900299 0.6634846093718149 0.5786801906327832 0.09313950929493002 0.1862615602393111 13.234129894786856 0.03184056751865233 0.03181791139088004 2.4570168953069856e-07 6.609591857148993 -0.20715287941821503 WRS(ph)LQQLAEER ddPTM_PC-9_AZD4547_30min_R2 3 WRSLQQLAEER 11 1 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 1 WRS(1)LQQLAEER;WRS(1)LQQLAEER;WRS(1)LQQLAEER 82.48299999999999 0.0065559 49812300.0 41789.0 33859.9 51890.0 68239.0 64503.0 56222.0 42336.0 43779.0 42198.0 51839.0 True False 55077.032734802495 44804.45050856673 51201.90469567629 52507.55283204041 55547.871852826065 52706.42945225881 46103.82198430069 37013.96149133913 44428.50013107556 50024.132388563565 1.101009255032959 0.8956567234499374 1.02354408264324 1.0496444480873115 1.1104214945969824 1.0536200616706441 0.9216316162405022 0.739922108070408 0.8881413431816507 1.0 15.61033661999988 -7.424594002894793 4.337874024656955 0.8555430063706576 1.034673584460311 0.4535440950621301 0.08124382185747273 0.19096054890282652 6.134034143948449 0.035983319778236274 0.0232263065682547 3.7618891748993346e-08 7.424594002894793 0.17913057808965338 WRS(ph)LQQLAEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 WRSLQQLAEER 11 1 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 1 WRS(1)LQQLAEER;WRS(1)LQQLAEER;WRS(1)LQQLAEER;WRS(1)LQQLAEER 90.229 0.0041762 36310800.0 41382.899999999994 32668.8 41135.899999999994 51000.8 54849.6 47818.9 52284.5 45595.6 48255.9 38175.5 True False 48388.20762046821 35911.94256342231 42116.735864769515 48143.39052282452 44102.21462114811 45311.19270363766 47331.73365300029 44398.76381253152 48961.55124630639 45096.41595290829 1.0729945295652177 0.7963369550458994 0.9339264545712392 1.0675657811276624 0.9779538725915964 1.0047626124203228 1.0495675244442089 0.9845297652677035 1.085708258887674 1.0 15.460725159095942 -5.657856130461182 6.82613260892619 1.021738004974312 0.9181866020071531 0.2462984272655635 0.0706457748124347 0.2563232187826902 14.818471955277518 0.018047552053202007 0.03140923443258881 2.198588082513866e-06 5.657856130461182 -0.10355140296715903 WRS(ph)LQQLAEER ddPTM_PC-9_Lapatinib_30min_R1 1 WRSLQQLAEER 11 1 Q13813-3;Q13813;A0A0D9SF54;A0A0D9SGF6;Q13813-2 Q13813-3 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 1 WRS(1)LQQLAEER 72.815 0.012406 14314000.0 17332.0 11329.0 13134.0 10140.0 12321.0 12809.0 9744.1 8814.9 13870.0 7266.5 True False 17084.842501700477 11302.768396551679 12054.173218706143 10885.729426048398 11596.303004018013 12261.188929237376 10248.601819752532 9224.472434374566 12307.814542424974 8522.504842997372 2.0046738390226273 1.326226104270125 1.4143932377592736 1.277292254634833 1.3606683971023223 1.4386837150713905 1.2025339977569423 1.082366347019911 1.4441545964667712 1.0 13.057061798853217 -2.707634045578999 1.3415367770339126 1.2776546680051033 199.99997290236 0.6932217643268022 0.14347983954369026 219.16250811891572 1.9152383564883355 0.040158974027954035 132528.52032397996 0.0019604959723500443 2.707634045578999 198.7223182343549 WRSEGADPAKFS(ph)DLDEQCDSS(ph)SLS(ph)S(ph)KT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 WRSEGADPAKFSDLDEQCDSSSLSSKTR 28 3 F5H212;P15822 F5H212 HIVEP1 Zinc finger protein 40 5 WRS(0.118)EGADPAKFS(0.779)DLDEQCDS(0.186)S(0.524)S(0.524)LS(0.91)S(0.979)KT(0.979)R 40.141999999999996 0.026612 8562600.0 11772.0 11590.0 7945.5 8825.4 12985.0 10928.0 10414.0 7463.5 9417.6 10482.0 True False 15515.251127188858 15336.240845197073 7840.137478502527 6790.840381070779 11182.256887415255 10244.670432469218 11340.825825408801 6310.187569168079 9915.395109588551 10115.028370472493 1.5338811280530407 1.516183670820558 0.7750979227492072 0.6713614764437448 1.1055091965988137 1.0128167769034808 1.1211857653819954 0.6238427949039275 0.980263697384507 1.0 13.304212745899681 -5.253196130540946 24.495341536064956 0.9073196024533557 1.525032541098075 0.6955838814573869 0.16239844383532925 256.49737840416 762192.2393462984 0.04308122435207512 0.10976916438359656 5.5821804248365e-06 5.253196130540946 0.6177129386447192 WS(ph)DQGPAQTSR ddPTM_PC-9_AZD4547_30min_R2 2 WSDQGPAQTSR 11 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 WS(1)DQGPAQTSR;WS(0.999)DQGPAQT(0.001)SR 139.64 0.00011320000000000001 36357000.0 128987.0 139890.0 158343.0 159500.0 160011.0 147286.0 164762.0 153773.0 136830.0 128760.0 True False 170002.18290373028 185106.70680195146 156243.2683605216 122729.73925043517 137796.23464090892 138076.18313659081 179425.49881371265 130010.91620200727 144062.5544560184 124252.15159149405 1.368203131505114 1.4897666111290369 1.2574693183117285 0.9877473965516176 1.1090048170267826 1.1112578846163266 1.4440433949475013 1.0463474035399114 1.15943710117516 1.0 16.92291130862681 -5.484253212632112 5.15783262974642 1.1353999823278438 1.4213464477873003 0.49213045187510396 0.12374405707999472 0.16900778684226272 11.208927931433527 0.03362313593809692 0.0689580599113539 3.279040549972614e-06 5.484253212632112 0.28594646545945657 WS(ph)DQGPAQTSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WSDQGPAQTSR 11 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 WS(0.975)DQGPAQT(0.025)SR 107.11 0.0023510000000000002 9787100.0 40428.0 45900.0 40716.0 40355.0 90284.0 58959.0 44745.0 54933.0 51705.0 42135.0 True False 47271.66191060289 50456.64865746781 41686.8238562899 38094.04018267525 72593.49830911691 55867.08624861237 40506.42967425333 53491.06695632462 52461.08780875027 49773.74195952353 0.949730923366072 1.0137202201614584 0.8375264188533386 0.7653441088205438 1.4584697764566428 1.12242085985908 0.8138112201247304 1.0746844591235285 1.0539912360097843 1.0 15.603097231573715 WS(ph)DQGPAQTSR ddPTM_PC-9_Lapatinib_30min_R1 2 WSDQGPAQTSR 11 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 WS(0.999)DQGPAQT(0.001)SR;WS(1)DQGPAQTSR 124.16 0.00052534 47168000.0 309090.0 335920.0 205811.0 184232.0 237010.0 184207.0 186476.0 180649.0 240825.0 159784.0 True False 304682.31991983624 335142.19787886314 188890.0140334348 197781.0358599355 223069.53777958822 176328.89601748987 196130.81484592467 189042.61203159773 213700.75250032428 187402.45150120318 1.6258182189141752 1.7883554627710483 1.007937796545965 1.0553812624946675 1.1903234775888514 0.9409102954896926 1.046575502480369 1.0087520761721946 1.1403306135456412 1.0 17.515780300141998 -5.263492465489 24.999921253093834 1.0504491178320137 1.7070868806170787 0.9216038335095043 0.07679960759182869 38.37196557045222 467252.6522313554 0.019272299203925942 0.04358564854927279 5.451393531492179e-06 5.263492465489 0.656637762785065 WS(ph)GNEPTDEFSDLPLR ddPTM_PC-9_AZD4547_30min_R2 2 WSGNEPTDEFSDLPLR 16 0 E9PD99;Q96II8-3;Q96II8-4;Q96II8;Q96II8-2 E9PD99 LRCH3 Leucine-rich repeat and calponin homology domain-containing protein 3 1 WS(1)GNEPTDEFSDLPLR;WS(1)GNEPTDEFSDLPLR 185.28 6.7908e-08 9534000.0 10442.9 16391.6 16206.6 17169.2 15864.9 19214.4 16415.7 20691.7 15240.6 13792.8 True False 13763.524974186252 21689.864144791405 15991.689894795669 13211.106201495726 13662.332483107764 18012.920530530428 17876.665498575305 17494.273212963784 16046.187001698438 13309.918270201586 1.0340803523189324 1.6296016026898488 1.2014867086447907 0.9925760574407823 1.0264775640054205 1.3533456903982637 1.343108585316997 1.3143787105087028 1.2055811820890625 1.0 13.700214091930969 -11.947264560727906 1.4600407558495931 4.894665379253922e-05 1.2400860862010934 0.1275263434245033 0.1823982846210075 535120.7736514312 48671.47949067888 1751407.3931983546 0.05334516689264549 1.1291078824282598e-12 11.947264560727906 1.2400371395473009 WS(ph)GNEPTDEFSDLPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 WSGNEPTDEFSDLPLR 16 0 E9PD99;Q96II8-3;Q96II8-4;Q96II8;Q96II8-2 E9PD99 LRCH3 Leucine-rich repeat and calponin homology domain-containing protein 3 1 WS(0.969)GNEPT(0.031)DEFSDLPLR;WS(0.99)GNEPT(0.01)DEFSDLPLR;WS(0.586)GNEPT(0.407)DEFS(0.007)DLPLR 144.25 2.9306e-05 7160600.0 10468.3 9607.599999999999 12687.4 10808.1 14400.399999999998 8772.1 12018.8 6890.900000000001 7852.9 10198.8 True False 12240.376431650448 10561.379033583611 12989.91573323244 10202.557197332984 11578.744994136345 8312.075633600512 10880.292255423305 6710.021176512072 7967.7338062727895 12047.761706343621 1.0159875942105834 0.8766258240335737 1.078201582157185 0.8468425460275277 0.9610702200425892 0.6899269620533645 0.903096568526451 0.5569516844758792 0.6613455677893649 1.0 13.556477519771846 -6.656480565048603 1.4862994244730858 0.7349294115369184 0.9676486581030308 0.3065133301883515 0.13537971354173808 0.4339454604452896 1.990194517290288 0.05599870480434822 0.055408925783937114 2.2055628345092916e-07 6.656480565048603 0.23271924656611243 WS(ph)GNEPTDEFSDLPLR ddPTM_PC-9_Lapatinib_30min_R1 3 WSGNEPTDEFSDLPLR 16 0 E9PD99;Q96II8-3;Q96II8-4;Q96II8;Q96II8-2 E9PD99 LRCH3 Leucine-rich repeat and calponin homology domain-containing protein 3 1 WS(0.955)GNEPT(0.045)DEFSDLPLR;WS(0.987)GNEPT(0.013)DEFSDLPLR;WS(0.999)GNEPT(0.001)DEFSDLPLR 180.62 3.1714e-29 8188000.0 16554.5 25281.5 21304.4 20346.199999999997 25341.0 25080.9 24939.5 25574.8 22643.5 21277.5 True False 16318.429794276515 25222.962240040724 19552.834469362206 21842.527420933526 23850.4922023229 24008.248373433522 26230.745280089297 26763.098573397594 20093.150583374194 24955.287524513384 0.653906703268678 1.0107261723698597 0.7835146940365086 0.8752665101324832 0.9557290084874698 0.9620505614231215 1.0511097199069752 1.0724420044092224 0.8051660620474458 1.0 14.60705790562087 -6.259838222345876 2.084867603148603 0.9868460312367885 0.832992100112331 0.31366539051133857 0.10565153531864416 0.41275918422468333 3.52263766853546 0.034737516770603646 0.04501384508641937 5.497456197103736e-07 6.259838222345876 -0.15385393112445744 WS(ph)IPADGR ddPTM_PC-9_AZD4547_30min_R2 1 WSIPADGR 8 0 E5RJF9;P55040 E5RJF9 GEM GTP-binding protein GEM 1 WS(1)IPADGR 70.399 0.038245 1786700.0 8811.4 7425.6 10462.0 16659.0 14581.0 14312.0 10139.0 13528.0 12011.0 11473.0 True False 11613.241911494377 9825.779984477605 10323.267044250633 12818.524928984305 12556.679836380574 13417.068377516425 11041.351358154388 11437.558442514346 12645.87693905751 11071.33376210941 1.0489469616786007 0.8874974050647272 0.932432104935815 1.1578121664848087 1.1341614394604036 1.211874618344094 0.9972918887101359 1.0330786414965019 1.1422180209521662 1.0 13.434541413418827 -5.751852046514614 24.999330824569174 1.1002382059421194 0.9494126376966758 0.41542073372015653 0.07607596605828991 188.60210648115236 491781.85548601235 0.021176252165648845 0.03608927674490516 1.770712093784886e-06 5.751852046514614 -0.15082556824544358 WS(ph)IPADGR ddPTM_PC-9_Lapatinib_30min_R1 1 WSIPADGR 8 0 E5RJF9;P55040 E5RJF9 GEM GTP-binding protein GEM 1 WS(1)IPADGR 76.282 0.025177 1977500.0 11290.0 10552.0 12783.0 11491.0 12916.0 11829.0 9816.2 7808.1 10057.0 9763.0 True False 11129.002529667567 10527.56749231294 11732.031083806967 12336.086472852285 12156.306273833014 11323.101244745796 10324.434804964523 8170.892830870463 8924.27475509502 11450.521541620226 0.9719210159306713 0.9193963309048813 1.0245848663891433 1.0773383926673747 1.0616377803969372 0.9888720966629088 0.9016562928978723 0.7135825910785805 0.7793771421377766 1.0 13.483125690393358 -7.4229502591423335 3.258684397189374 0.8092721234506781 1.009926315714247 0.4867984129182692 0.08061488486036454 0.19491046502510467 3.9159963571785075 0.0384535017664548 0.023793932925664136 3.7761543771057176e-08 7.4229502591423335 0.20065419226356895 WS(ph)NSQPADLAHMGR ddPTM_PC-9_AZD4547_30min_R2 2 WSNSQPADLAHMGR 14 0 Q9BRG2;Q9BRG2-2;M0QZQ6 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 WS(0.5)NS(0.5)QPADLAHMGR;WS(0.907)NS(0.093)QPADLAHMGR 96.447 0.0020437999999999997 33186600.0 45735.0 34755.0 55434.0 61159.0 56628.0 54356.0 45100.0 68091.0 56144.0 42729.0 True False 60277.778652903726 45988.87407893224 54698.90894006782 47059.73744713074 48766.17967043136 50957.11072724165 49113.812629723165 57569.10052552077 59111.657219752335 41233.070715695416 1.461879447895665 1.1153395388868412 1.326578593120561 1.1413105216346984 1.1826958027617491 1.2358310900149565 1.1911267285516025 1.3961875631932266 1.4335982305885215 1.0 15.331514285387163 -7.738851361946534 24.974208158502837 1.3111697862918792 1.2294631060661247 0.0 0.1438696152644232 659.2050962598048 728844.260181653 0.06365285848372355 0.03671547478705859 1.8245200406794134e-08 7.738851361946534 -0.08170668022575445 WS(ph)NSQPADLAHMGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 WSNSQPADLAHMGR 14 0 Q9BRG2;Q9BRG2-2;M0QZQ6 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 WS(0.581)NS(0.419)QPADLAHMGR;WS(0.916)NS(0.084)QPADLAHMGR 105.79 0.00065043 40495000.0 41721.0 55199.0 53432.0 78267.0 70966.0 43569.0 64002.0 54745.0 45157.0 40040.0 True False 48783.54127268884 60678.79192251778 54706.02152198844 73881.95373503759 57060.72173369352 41284.164941159004 57939.26722564671 53308.001757122154 45817.33569634918 47298.93504353441 1.0313877305649268 1.2828786074500076 1.1566015486741186 1.5620215057069657 1.2063849150340122 0.8728349782751059 1.224959233697732 1.1270444399658668 0.9686758413097134 1.0 15.529520080562154 -6.538103160671117 24.88191579096354 1.0562092267368515 1.2691596812221155 0.3196123301407652 0.15267710008899515 284.7173593967715 465322.5816777812 0.05036664634410469 0.050383887324852626 2.896655445379927e-07 6.538103160671117 0.21295045448526406 WS(ph)PPQNYK ddPTM_PC-9_AZD4547_30min_R2 1 WSPPQNYK 8 0 H3BRF9;Q96K21-3;Q96K21-2;Q96K21;H3BRM1 H3BRF9 ZFYVE19 Abscission/NoCut checkpoint regulator 1 WS(1)PPQNYK 79.48899999999999 0.020640000000000002 35609000.0 120350.0 129140.0 185290.0 185260.0 177840.0 183450.0 156440.0 203180.0 164600.0 165260.0 True False 158618.79656448984 170881.97952965926 182832.9335336649 142551.16923846785 153149.98574185083 171978.84249967767 170362.85693556283 171783.19961192072 173300.41996243986 159474.29770122946 0.9946354920568932 1.0715330432105228 1.146472730522364 0.8938817809095068 0.960342750834827 1.0784110353749614 1.0682778315458255 1.0771842365078268 1.0866981228982318 1.0 17.28296439957471 -6.8164131810106605 24.99997780883445 1.0673235718382592 1.0173595304184602 0.11570299994410771 0.06614225435405809 219.57604898182524 99852.89457310192 0.024913198669661393 0.02197138534737433 1.526113446771062e-07 6.8164131810106605 -0.04996404141979904 WS(ph)TTAGFLK ddPTM_PC-9_AZD4547_30min_R2 1 WSTTAGFLK 9 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 WS(0.994)T(0.006)TAGFLK 106.4 0.0025719000000000002 44628000.0 53079.0 67675.0 67959.0 71047.0 62590.0 57611.0 69661.0 80856.0 70525.0 61395.0 True False 69957.01788821425 89549.62029324516 67057.81925637824 54668.211815207906 53900.458882042425 54008.575062681615 75860.69404876145 68361.56308603912 74252.80752035894 59245.579737183616 1.180797254386692 1.5114987597470022 1.1318619811612969 0.9227390812566753 0.9097802590699186 0.9116051408774525 1.2804447924264277 1.1538677381383466 1.2533054423595507 1.0 15.854419899313369 -5.453583776108621 7.259133056146612 1.061784517021778 1.342985283456307 0.3675346568243669 0.14715595524979797 0.2955010838228637 26.925522575245466 0.041290339582879095 0.08610218141317404 3.518975343730558e-06 5.453583776108621 0.28120076643452907 WS(ph)TTAGFLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WSTTAGFLK 9 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 WS(0.88)T(0.12)TAGFLK 152.04 0.00012582 34085000.0 47887.0 54078.0 43673.0 39097.0 43436.0 31407.0 38534.0 35145.0 31428.0 28807.0 True False 55993.323288637584 59446.506450948684 44714.32995077482 36906.52184418424 34925.027607934964 29759.96163113637 34883.78055799927 34222.48098920555 31887.575044065434 34029.48106391348 1.6454357086278237 1.7469119302553413 1.3139880054824602 1.0845455378783813 1.0263167852116077 0.8745346887671256 1.025104687681874 1.0056715506454412 0.9370573410794845 1.0 15.054497530493071 -5.536204005212139 1.84072061074907 0.9786320180184872 1.7201814907285173 0.9597011921031549 0.057689257597298364 0.060999589866635215 0.4028647293185036 0.01690048953800455 0.04566019268506748 2.909350160751327e-06 5.536204005212139 0.7415494727100301 WS(ph)TTAGFLK ddPTM_PC-9_Lapatinib_30min_R1 2 WSTTAGFLK 9 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 WS(0.522)T(0.474)T(0.004)AGFLK;WS(0.762)T(0.235)T(0.002)AGFLK 126.71 0.0013858 64053000.0 109658.0 181959.0 179381.0 161936.0 193996.0 175959.0 175678.0 163451.0 167888.0 148533.0 True False 108094.25681118558 181537.68511502753 164632.98661068393 173845.31364266045 182585.5366908108 168433.64375046274 184773.74724094407 171045.53016721175 148978.68550098373 174206.73114221846 0.6204941456764943 1.0420819214317514 0.9450437737464993 0.9979253528426353 1.0480969104560725 0.9668607099513123 1.0606579093094797 0.9818537380600639 0.855183290129937 1.0 17.410440843482 -4.756555642679377 24.999996828725134 0.9904234230366009 0.6204935812676405 0.7918582365530572 0.05661588368973998 65.14901308629295 333461.12426842656 0.01387709326815243 0.11133231784238126 1.751637996460657e-05 4.756555642679377 -0.3699298417689604 WSAEASGKPSPSDPGSGTATMMNS(ph)SSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WSAEASGKPSPSDPGSGTATMMNSSSR 27 1 Q5JRA6-4;Q5JRA6-2;Q5JRA6 Q5JRA6-4 MIA3 Melanoma inhibitory activity protein 3 1 WSAEASGKPSPSDPGS(0.003)GT(0.009)AT(0.03)MMNS(0.343)S(0.343)S(0.271)R 44.683 0.019114 25924000.0 50848.0 63301.0 57284.0 48464.0 74860.0 47300.0 60677.0 33539.0 36576.0 37891.0 True False 59455.56210622184 69585.10493826517 58649.86781077979 45748.719202407956 60191.72038700644 44819.504733108864 54929.23529656208 32658.63678750792 37110.854805006245 44760.338355009015 1.3283090407999187 1.5546152575157663 1.3103088574891533 1.0220816214470894 1.344755705589311 1.001321848320953 1.2271854350362634 0.7296333760589898 0.829101301930915 1.0 15.449933321611043 -6.480849024003873 0.5307199417197085 0.8577093666064302 1.4743379546070878 0.5756840459696383 0.16001205962488307 0.7587668793855483 0.44892605175415445 0.13401820106423112 0.22394560014533288 3.3048440904292656e-07 6.480849024003873 0.6166285880006577 WSAEASGKPSPSDPGSGTATMMNSS(ph)SR ddPTM_PC-9_Lapatinib_30min_R1 1 WSAEASGKPSPSDPGSGTATMMNSSSR 27 1 Q5JRA6-4;Q5JRA6-2;Q5JRA6 Q5JRA6-4 MIA3 Melanoma inhibitory activity protein 3 1 WSAEASGKPSPSDPGSGTAT(0.001)MMNS(0.063)S(0.541)S(0.395)R 77.175 6.3913e-05 5088200.0 27949.0 31309.0 18202.0 12363.0 14062.0 19480.0 15590.0 16211.0 19260.0 8963.6 True False 27550.442134781133 31236.505934119206 16705.501821751877 13272.216261759013 13234.900806955708 18646.88581009792 16397.173917544147 16964.222241165065 17090.735983208735 10512.946316753761 2.620620452600988 2.9712418377272343 1.5890409137854595 1.2624640002782086 1.2589145238822492 1.773706936977473 1.55971251288643 1.613650610403132 1.6256847003938755 1.0 13.359879429523241 -5.292175081942789 6.871394883229461 1.4799195124062645 2.797138236521643 0.843277039995372 0.2302400273029412 0.06320601954246782 10.91948782725161 0.059713651402230464 0.1296776120720699 5.102992359214582e-06 5.292175081942789 1.3172187241153785 WSAEASGKPSPSDPGSGTATMMNSSS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 WSAEASGKPSPSDPGSGTATMMNSSSR 27 1 Q5JRA6-4;Q5JRA6-2;Q5JRA6 Q5JRA6-4 MIA3 Melanoma inhibitory activity protein 3 1 WSAEAS(0.001)GKPS(0.002)PS(0.018)DPGS(0.014)GT(0.045)AT(0.035)MMNS(0.035)S(0.229)S(0.62)R;WSAEASGKPSPSDPGSGT(0.001)AT(0.001)MMNS(0.063)S(0.14)S(0.795)R 62.647 0.00050544 36833000.0 124164.0 164438.0 224513.0 162793.0 170476.0 155891.0 195003.0 222446.0 197959.0 147580.0 True False 163645.56922836197 217589.3677396477 221535.810925812 125263.58897677792 146808.35002995783 146143.11112628665 212357.88922913355 188072.08200055815 208422.70859869194 142413.26911985604 1.1490893386531045 1.527872852609843 1.5555840568435084 0.8795780740863071 1.0308614565009588 1.026190270256991 1.4911383647152403 1.320607856015687 1.4635062440936026 1.0 17.119724047718393 -11.505221855324008 2.901108078123666 0.7604570211990166 1.2695623079594127 0.11303679913773146 0.22817933965903056 189760852.70095098 295214966.46631944 300800399.01811475 0.06144291042581742 3.1244828461771206e-12 11.505221855324008 0.5091052867603961 WSAEASGKPSPSDPGSGTATMMNSSS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 WSAEASGKPSPSDPGSGTATMMNSSSR 27 1 Q5JRA6-4;Q5JRA6-2;Q5JRA6 Q5JRA6-4 MIA3 Melanoma inhibitory activity protein 3 1 WSAEASGKPSPSDPGSGTAT(0.003)MMNS(0.05)S(0.283)S(0.663)R 55.668 0.0019034000000000002 13876000.0 87140.0 109820.0 65139.0 40953.0 49245.0 54115.0 55570.0 52687.0 74516.0 29981.0 True False 85897.36762048109 109565.71853732044 59783.52286381146 43964.82023520313 46348.50591939509 51800.627598226274 58447.14269390177 55135.03036334982 66123.22339173328 35163.17590282861 2.4428216568905343 3.115922146511991 1.7001741546047986 1.2503085715777593 1.318097831876065 1.47314985828852 1.6621690502421353 1.5679764113375956 1.8804678955752163 1.0 15.101777758686639 -5.361801793220561 5.083597498127635 1.4797522397927823 2.7714016248375386 0.7836251956726628 0.2744325230730652 0.0876610926247435 3.469040308019023 0.07063551935247378 0.15266450997353093 4.347085746721365e-06 5.361801793220561 1.2916493850447563 WSEPWVPVEALPPS(ph)PLELSR ddPTM_PC-9_AZD4547_30min_R2 2 WSEPWVPVEALPPSPLELSR 20 0 O43379;O43379-4 O43379 WDR62 WD repeat-containing protein 62 1 WSEPWVPVEALPPS(1)PLELSR;WSEPWVPVEALPPS(0.999)PLELS(0.001)R 207.1 1.5987999999999997e-72 0.0 3763.2 3586.7999999999997 5671.6 8309.2 7929.7 5984.9 5240.1 5564.4 5752.299999999999 7572.7 True False 4959.819320577395 4746.1629563030965 5596.390878242394 6393.64231586028 6828.7980315854265 5610.663256889186 5706.458748581204 4704.549837191514 6056.354834446803 7307.582077950488 0.6787223554481709 0.6494847277355826 0.7658334615397134 0.8749326723475496 0.9344811948387526 0.7677865533414266 0.7808956078371766 0.643790215013359 0.8287768470943251 1.0 12.835178412974924 -12.591582289034632 1.196144750824781 5.359546103138434 0.7703254509901732 0.3729670955096478 0.089691554273391 202688.4529386756 3902.2183359126047 2391909.8669318166 0.028488012736511536 2.561047957136305e-13 12.591582289034632 -4.589220652148261 WSGNEPT(ph)DEFSDLPLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WSGNEPTDEFSDLPLR 16 0 E9PD99;Q96II8-3;Q96II8-4;Q96II8;Q96II8-2 E9PD99 LRCH3 Leucine-rich repeat and calponin homology domain-containing protein 3 1 WS(0.261)GNEPT(0.636)DEFS(0.103)DLPLR 136.36 2.4833e-05 1478200.0 3938.9 4168.3 4792.2 4432.8 6734.9 4855.1 4354.2 4179.4 4282.3 3057.8 True False 4605.677973178828 4582.101276664991 4906.464222519704 4184.444587331502 5415.2446918841815 4600.490009084922 3941.73865432191 4069.69517844034 4344.92053618434 3612.1549344685172 1.2750499512713995 1.2685229066286408 1.3583205348420715 1.1584344147040828 1.4991728732923153 1.2736136994527412 1.0912429632262954 1.1266668380156688 1.202861066319028 1.0 11.818644059650179 -7.191859357677025 5.184539823514365 1.1158602087267473 1.3103587052160817 0.5278266257356188 0.09290815389505278 0.18163154912862034 9.33953722304498 0.035344349411622886 0.02694728190608361 6.428958796002205e-08 7.191859357677025 0.19449849648933437 WSLQSEAHR ddPTM_PC-9_AZD4547_30min_R2 4 WSLQSEAHR 9 0 Q16658 Q16658 FSCN1 Fascin 0 ;;; 218.94 6.0644e-07 44742700.0 98826.7 88304.0 312462.0 489503.0 395179.0 362919.0 205577.0 404973.0 252925.0 306270.0 False True 130251.53487694146 116846.54112116319 308318.54972095625 376655.6460959602 340315.2171360699 340225.6175586831 223872.95474458064 342393.7282037521 266294.09914337896 295547.5805213324 0.44071257374932227 0.3953561078559711 1.0432112121408554 1.2744331908640798 1.151473534433168 1.1511703697879736 0.7574853238509989 1.158506280443187 0.9010193846745366 1.0 18.173030884556447 -5.267705203240214 9.582052396426555 1.0646466532701735 0.41753810528026586 0.768942181258535 0.13950706092041265 0.0659305983010854 85.42956417744684 0.037269025389002924 0.08423921621102624 5.398769637467392e-06 5.267705203240214 -0.6471085479899077 WSLQSEAHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 WSLQSEAHR 9 0 Q16658 Q16658 FSCN1 Fascin 0 ; 200.56 0.0031487 16262400.0 25433.0 44224.0 80910.0 86064.0 107194.0 84116.0 80509.0 75592.0 81364.0 53650.0 False True 29738.304575352802 48614.266453765944 82839.20125288371 81242.1131032527 86190.10519856772 79704.80888224496 72882.60468531602 73607.79009634432 82553.79457443474 63376.3203068337 0.4692336890399457 0.7670730364022728 1.307100204805538 1.2819001278383242 1.3599733272818944 1.257643367370614 1.1499974175284722 1.1614399469703416 1.302596840188167 1.0 15.951656277370045 -5.072527601155153 3.016427774029906 1.2385103520161647 0.4910097062109552 0.8592347807432517 0.10165543011081969 0.08767683746395147 1.4811371237224478 0.02686189976638764 0.11076066498421988 8.461987877734165e-06 5.072527601155153 -0.7475006458052095 down WSLQSEAHR ddPTM_PC-9_Lapatinib_30min_R1 3 WSLQSEAHR 9 0 Q16658 Q16658 FSCN1 Fascin 0 ;; 218.94 6.0644e-07 13460500.0 89667.0 87682.0 197139.0 127670.0 179965.0 197163.0 125104.0 138890.0 207938.0 100399.0 False True 88388.33213708615 87478.97771616603 180930.99239854628 137059.2776946351 169379.81252480324 188730.798099401 131581.27298142668 145343.3364428734 184517.83275578698 117752.83337674136 0.7506259476092122 0.7429033782676261 1.53653196454026 1.163957365307077 1.4384351328760407 1.6027707587771665 1.117436151709762 1.234308613006859 1.5669927208072862 1.0 16.845402248919406 -5.249675719643887 24.76193993536884 1.340650217507935 0.7467645295552233 0.5931104186748235 0.19398337768785012 420.31171897647476 884731.3406207655 0.04761518453348645 0.12375468021335267 5.627613727638371e-06 5.249675719643887 -0.5938856879527116 WSNS(ph)QPADLAHMGR ddPTM_PC-9_AZD4547_30min_R2 1 WSNSQPADLAHMGR 14 0 Q9BRG2;Q9BRG2-2;M0QZQ6 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 WS(0.262)NS(0.738)QPADLAHMGR 81.639 0.007061499999999999 26791000.0 19122.0 19656.0 24855.0 26494.0 26814.0 28924.0 24448.0 33952.0 22449.0 23101.0 True False 25202.398237691574 26009.417605970124 24525.40646003149 20386.21762821961 23091.33894333098 27115.37770760796 26623.824637948364 28705.498539344113 23635.608309458177 22292.241021397163 1.130545745199018 1.1667475504595988 1.1001768030630399 0.9144983498362474 1.035846459813834 1.2163594356252168 1.1943090249380284 1.2876901210511404 1.060261652777376 1.0 14.444254036431536 -6.757495349076109 24.999616071459997 1.1723662427721182 1.068048185617921 0.13152821132574355 0.09863484288429902 172.30389111408627 1092163.9629161658 0.034231106740881326 0.03303642043572685 1.7478519803235668e-07 6.757495349076109 -0.10431805715419729 WSNS(ph)QPADLAHMGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 WSNSQPADLAHMGR 14 0 Q9BRG2;Q9BRG2-2;M0QZQ6 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 WS(0.31)NS(0.69)QPADLAHMGR;WS(0.293)NS(0.707)QPADLAHMGR 113.81 0.00012663 18711600.0 56998.0 63656.0 72859.0 54096.0 76440.0 59477.0 67490.0 48054.0 50951.0 50040.0 True False 66646.63563818499 69975.34699215183 74596.23487929616 51065.17650159832 61462.13072913129 56357.92141672553 61096.858614713485 46792.63341742163 51696.06198517808 59111.85588357796 1.1274664725372003 1.1837785490946138 1.261950479548722 0.8638736804706699 1.0397597877857574 0.9534114700733408 1.0335804501730588 0.7915947269458212 0.8745464207213279 1.0 15.85115989589198 -5.761228245251211 24.999999988413403 0.9370269089059554 1.1903365293548909 0.6810501251964235 0.07977512723252994 3.312667935970715 392139.26075180096 0.022922121195516145 0.036704522570316166 1.7328930293345746e-06 5.761228245251211 0.25330962044893546 WSNS(ph)QPADLAHMGR ddPTM_PC-9_Lapatinib_30min_R1 6 WSNSQPADLAHMGR 14 0 Q9BRG2;Q9BRG2-2;M0QZQ6 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 WS(0.434)NS(0.566)QPADLAHMGR;WS(0.078)NS(0.922)QPADLAHMGR;WS(0.116)NS(0.884)QPADLAHMGR;WS(0.161)NS(0.839)QPADLAHMGR;WS(0.183)NS(0.817)QPADLAHMGR;WS(0.014)NS(0.986)QPADLAHMGR 110.26 0.00029003 46207400.0 102668.8 127050.7 140993.3 125212.1 142765.5 154469.8 128018.5 122806.1 137802.8 105084.1 True False 101204.72408484816 126756.52191012171 129401.375123877 134420.615529321 134368.31397777225 147863.48674069106 134646.67153066874 128512.11973170943 122281.9975361845 123247.74666923854 0.8211486767092991 1.0284692851245363 1.049928932746763 1.0906537373869172 1.0902293762690698 1.1997256804825331 1.0924878966917069 1.0427137469425625 0.9921641639774086 1.0 16.911201744578882 -4.452179650722677 1.5840998336241547 1.079751521692996 0.48298455370391624 0.6370644899032432 0.055664232444830555 1.7292764346988034 2.1154140173770024 0.016414436711990953 2.0588868757441645 3.530371018753111e-05 4.452179650722677 -0.5967669679890798 WSSTVT(ph)SPR ddPTM_PC-9_Lapatinib_30min_R1 1 WSSTVTSPR 9 0 M0QZ79;M0QXD7;M0R025;M0QYG0;M0QYA8;Q8IV63-2;Q8IV63 M0QZ79 VRK3 Inactive serine/threonine-protein kinase VRK3 1 WSS(0.01)T(0.01)VT(0.49)S(0.49)PR 81.95 0.040307 5295500.0 61291.0 58442.0 70240.0 69453.0 67254.0 64388.0 51810.0 58724.0 68364.0 49749.0 True False 60416.97910060714 58306.68113966578 64465.13833424084 74560.80530841621 63298.251946451404 61634.275335758975 54492.468291723024 61452.531422501874 60664.1264151652 58348.048363624366 1.035458439399536 0.9992910264332958 1.1048379533192754 1.2778628831551335 1.0848392315022677 1.056321112090243 0.9339210105559416 1.0532062878869641 1.039694182007718 1.0 15.832396780756985 -6.9055966626360625 3.634953915732624 1.0095399517091694 1.1048142017421736 0.2577437707564241 0.07427591304537802 0.3668205451641489 9.427297311509859 0.030515561395802752 0.026476635211272435 1.2428059888269425e-07 6.9055966626360625 0.09527425003300416 WSSTVTS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WSSTVTSPR 9 0 M0QZ79;M0QXD7;M0R025;M0QYG0;M0QYA8;Q8IV63-2;Q8IV63 M0QZ79 VRK3 Inactive serine/threonine-protein kinase VRK3 1 WSSTVT(0.003)S(0.997)PR 101.46 0.0034914 4890200.0 53125.0 49552.0 51297.0 55351.0 64084.0 63523.0 64923.0 59713.0 52729.0 51128.0 True False 62118.01323342186 54471.19508224061 52520.115024955805 52249.862920363215 51527.200230843206 60191.742054149574 58773.02343818417 58145.59702115329 53500.061871532576 60397.10167097467 1.0284932805521398 0.9018842556217908 0.8695800555309702 0.8651054682227108 0.8531402800013148 0.9965998431854589 0.9731099972042038 0.9627216441264532 0.8858051196394306 1.0 15.882191698880623 -6.768019695957778 24.999271172242928 0.961908837453963 0.8995099881020812 0.23213897406257145 0.0542625697689936 246.59193008312596 936821.2459285564 0.019620044252371006 0.017697227857873 1.7060050171595055e-07 6.768019695957778 -0.06239884935188189 WSSTVTS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 WSSTVTSPR 9 0 M0QZ79;M0QXD7;M0R025;M0QYG0;M0QYA8;Q8IV63-2;Q8IV63 M0QZ79 VRK3 Inactive serine/threonine-protein kinase VRK3 1 WS(0.001)S(0.008)T(0.008)VT(0.255)S(0.728)PR 76.17 0.024906 4386000.0 80652.0 92223.0 93401.0 79961.0 81959.0 81603.0 61792.0 66999.0 88698.0 65278.0 True False 79501.8876902346 92009.46330966432 85721.93031828642 85841.59868207671 77138.33275759371 78113.02991588406 64991.28740942195 70112.01813187441 78707.89720865252 76561.21532253252 1.0384094264349617 1.2017764206335069 1.119652162745356 1.1212152043361427 1.0075379868596646 1.0202689388721713 0.8488800384846366 0.9157641742821178 1.0280387644981417 1.0 16.224326110704038 -6.490458675388606 1.6956642997496696 0.9454809083771482 1.1298586931348054 0.5940329729328148 0.061541657119762255 0.23541955396610226 1.3661377095576752 0.02356999727506217 0.026429126148165803 3.232520774215339e-07 6.490458675388606 0.1843777847576572 WST(ph)PTKDCTSGPYTAQIIPGTGNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WSTPTKDCTSGPYTAQIIPGTGNK 24 1 P51587 P51587 BRCA2 Breast cancer type 2 susceptibility protein 1 WS(0.15)T(0.442)PT(0.098)KDCT(0.087)S(0.087)GPY(0.025)T(0.11)AQIIPGTGNK 54.096000000000004 0.006541 6659100.0 21550.0 21684.0 21937.0 30538.0 33689.0 30908.0 30630.0 30701.0 30167.0 23329.0 True False 25197.989368098642 23836.644215436423 22460.061276535784 28827.054865531823 27087.88228851002 29287.130069575673 27728.50465800378 29895.131280398364 30608.13530464304 27558.363027737607 0.9143500048510415 0.8649513830500288 0.8149998334055487 1.0460365456582916 0.9829278415864525 1.0627311223129638 1.0061738656281916 1.0847934345849495 1.1106659446294334 1.0 14.750202573763463 -5.770672163144984 24.999981773398826 1.0423588827610129 0.8647855032672289 0.781097237477917 0.04297216804873948 84.49383332709131 228787.6894206287 0.012433514862114883 0.018732994415392897 1.6956172919095267e-06 5.770672163144984 -0.17757337949378393 WSTPT(ph)KDCTSGPYTAQIIPGTGNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WSTPTKDCTSGPYTAQIIPGTGNK 24 1 P51587 P51587 BRCA2 Breast cancer type 2 susceptibility protein 1 WS(0.071)T(0.275)PT(0.636)KDCT(0.006)S(0.002)GPYT(0.009)AQIIPGTGNK 85.397 0.00016059 0.0 21534.0 15562.0 18763.0 21452.0 23254.0 26419.0 23615.0 22981.0 19472.0 16216.0 True False 25179.28088411306 17106.89251432492 19210.381079073766 20250.11398832238 18697.545630235745 25033.54113200852 21378.016242205667 22377.773100382223 19756.741162595208 19155.83243421462 1.3144446199654491 0.8930383251719176 1.0028476259147954 1.05712524150886 0.9760758606783217 1.3068365062170624 1.1160055985884467 1.168196327527528 1.031369491795475 1.0 14.225496100305696 WSTT(ph)AGFLK ddPTM_PC-9_AZD4547_30min_R2 1 WSTTAGFLK 9 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 WS(0.276)T(0.276)T(0.448)AGFLK 89.679 0.022396 36452000.0 44104.0 53887.0 66238.0 53779.0 52936.0 66133.0 52485.0 75723.0 61283.0 52741.0 True False 58128.154579811184 71304.9189322809 65359.6408408596 41381.082427267385 45586.75014187248 61997.69305549838 57156.06332308248 64021.75029143365 64522.29426827587 50894.553643110994 1.142129175302814 1.401032405791275 1.2842168004691124 0.8130748668599171 0.8957097936557507 1.2181596775609072 1.1230290715167524 1.2579293010481 1.2677642232747925 1.0 15.63522365760913 -5.585817647207329 24.9999974778895 1.0891965659634018 1.289357186026882 0.24960614836739614 0.15294347451294982 91.55899944575944 36367.300903277035 0.045114109380947474 0.07813994262243838 2.595268842181311e-06 5.585817647207329 0.20016062006348023 WTDGSLS(ph)PPAKEPLASDSR ddPTM_PC-9_Lapatinib_30min_R1 2 WTDGSLSPPAKEPLASDSR 19 1 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 WT(0.004)DGS(0.083)LS(0.907)PPAKEPLAS(0.005)DS(0.001)R;WT(0.004)DGS(0.261)LS(0.735)PPAKEPLASDSR 98.76 0.00025278 37981300.0 94793.0 94437.0 89086.0 82586.0 93162.0 87881.0 77093.0 73196.0 92105.0 73837.0 True False 93441.23443709289 94218.33692869183 81761.69296190476 88659.64993881986 87682.39432353909 84122.53449061676 81084.49832105395 76596.9533751352 81731.16499135198 86599.62706838174 1.0790027347728508 1.0879762432959916 0.9441344695092416 1.0237878954006518 1.0125031399304105 0.9713960364308614 0.9363146362862178 0.8844951874290622 0.9437819510101877 1.0 16.402073191709825 -4.673811443875039 0.4528854374064655 0.9365373101069143 1.2160129919362717 0.5400213734124713 0.04172028908091585 4.221811355939287 0.6264738196449895 0.030929860374531767 0.6498694359660474 2.1192810564210905e-05 4.673811443875039 0.27947568182935734 WTGPEISPNTSGS(ph)SPVIHFTPSDLEVR ddPTM_PC-9_AZD4547_30min_R2 1 WTGPEISPNTSGSSPVIHFTPSDLEVR 27 0 A0AVK6 A0AVK6 E2F8 Transcription factor E2F8 1 WTGPEISPNTSGS(0.636)S(0.363)PVIHFTPSDLEVR 136.48 4.7064e-10 11943000.0 8107.8 4420.6 22256.0 28891.0 20608.0 18950.0 14898.0 22102.0 14905.0 18522.0 True False 10685.91174728354 5849.4725004554075 21960.87089818793 22230.62631150044 17746.93491997333 17765.05350432757 16223.893138749789 18686.643753433775 15692.84787083941 17873.550417658036 0.5978617285084264 0.32726975691838295 1.2286798305328224 1.2437722663952577 0.9929160410368374 0.9939297503408568 0.9077039961082113 1.045491428215205 0.8779927604834338 1.0 14.125538620598046 -5.258064184720819 24.999992817333947 1.037688278457883 0.462565708281854 0.7632619490973571 0.12781147361912837 134.68438787768426 997593.0695544181 0.034636404367389434 0.08421875753911248 5.519958533536094e-06 5.258064184720819 -0.575122570176029 WTGPEISPNTSGS(ph)SPVIHFTPSDLEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WTGPEISPNTSGSSPVIHFTPSDLEVR 27 0 A0AVK6 A0AVK6 E2F8 Transcription factor E2F8 1 WTGPEIS(0.002)PNT(0.028)S(0.138)GS(0.492)S(0.34)PVIHFTPSDLEVR 94.01899999999999 1.9266e-09 9333600.0 3555.8 5967.5 10552.0 12621.0 13334.0 13674.0 10129.0 11714.0 9984.0 10822.0 True False 4157.726709748735 6559.913962166429 10803.599698682841 11913.88628783408 10721.298418919898 12956.911368298743 9169.507792390481 11406.519912008938 10129.997112127696 12783.94293309514 0.3252303871746165 0.5131369872736281 0.8450913583722612 0.9319414479699645 0.8386534948591285 1.0135301319873558 0.7172675785850396 0.8922536631855323 0.792400057254879 1.0 13.64204525282125 -5.126532528607875 2.4609494142838786 0.8785005628249837 0.33007922216797997 0.8310052727134106 0.08504071666921367 0.11771901043051317 1.285818223814919 0.022086232074299043 0.09734852214099181 7.472526629547272e-06 5.126532528607875 -0.5484213406570038 down WTGPEISPNTSGSS(ph)PVIHFTPSDLEVR ddPTM_PC-9_AZD4547_30min_R2 1 WTGPEISPNTSGSSPVIHFTPSDLEVR 27 0 A0AVK6 A0AVK6 E2F8 Transcription factor E2F8 1 WTGPEISPNT(0.004)S(0.003)GS(0.177)S(0.815)PVIHFT(0.001)PSDLEVR 113.75 4.9685e-12 14269000.0 5495.4 6990.0 20936.0 31295.0 23184.0 17392.0 14365.0 25051.0 18181.0 21961.0 True False 7242.822888579139 9249.38080309988 20658.374960660618 24080.421252930188 19965.301784969994 16304.475490620849 15643.457171307613 21179.943564712223 19142.010542752854 21192.15207440816 0.3417691069386784 0.43645311578664625 0.9748125102220205 1.1362895645699866 0.9421082726694981 0.7693638396597902 0.738172183569728 0.9994239136425092 0.9032593988351435 1.0 14.371242481154036 -5.222660453088609 5.477931757130863 0.9280709267780305 0.3764006261467539 0.7964193547498839 0.11009081207823923 0.09067265420945657 7.323187188871419 0.031629645517280786 0.08446892957223419 5.988796375249281e-06 5.222660453088609 -0.5516703006312766 down WTGPEISPNTSGSS(ph)PVIHFTPSDLEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WTGPEISPNTSGSSPVIHFTPSDLEVR 27 0 A0AVK6 A0AVK6 E2F8 Transcription factor E2F8 1 WTGPEIS(0.021)PNT(0.086)S(0.06)GS(0.227)S(0.606)PVIHFTPSDLEVR 89.23899999999999 2.6816999999999995e-07 10558000.0 5388.5 7431.1 13144.0 13808.0 18416.0 18134.0 14098.0 12834.0 12945.0 11999.0 True False 6300.666622273764 8168.810497571 13457.402808897581 13034.382526140005 14807.517000362146 17183.021116917473 12762.535379318892 12497.121098747031 13134.296135466042 14174.323715968265 0.4445126800071363 0.5763104230763633 0.949421156068065 0.9195770314922296 1.044671851517018 1.2122639119325123 0.9003981872476282 0.8816731823803516 0.926625946934557 1.0 13.790992282625664 -5.185919604596967 2.377683379053652 0.9876953096241832 0.4415907042617056 0.8150270117417865 0.09046757876460823 0.1421201315435634 1.4750070908397044 0.027297193657564393 0.1093090441737366 6.51749032887273e-06 5.185919604596967 -0.5461046053624776 down WTGPEISPNTSGSS(ph)PVIHFTPSDLEVR ddPTM_PC-9_Lapatinib_30min_R1 2 WTGPEISPNTSGSSPVIHFTPSDLEVR 27 0 A0AVK6 A0AVK6 E2F8 Transcription factor E2F8 1 WTGPEIS(0.003)PNT(0.052)S(0.007)GS(0.153)S(0.785)PVIHFTPSDLEVR;WTGPEISPNT(0.001)S(0.004)GS(0.443)S(0.551)PVIHFTPSDLEVR 121.09 1.7154e-12 16368400.0 27923.1 21439.6 42436.0 27483.4 39570.0 42734.0 25729.0 30341.0 44942.0 25811.6 True False 27524.91147353059 21389.9579234451 38947.07588769712 29504.62091793477 37242.57039761324 40906.3664378195 27061.121727036134 31750.753625266138 39880.15869975945 30273.100668204923 0.9092200952656069 0.7065664715973556 1.2865241758536567 0.9746150961312904 1.2302198841735488 1.351244687029447 0.8938999022144353 1.0488107568912872 1.3173463510344872 1.0 14.885748827742594 -5.256184143085486 24.99689921079302 1.1359561755166827 0.8078932688102657 0.41843269623727364 0.15557724466297654 404.19620094975767 1922572.4374660812 0.03934233988083539 0.09774127583685574 5.543905986622819e-06 5.256184143085486 -0.328062906706417 WTLGFCDER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WTLGFCDER 9 0 M0R0U3;M0R261;O95336;M0R1L2 M0R0U3 PGLS 6-phosphogluconolactonase 0 98.58200000000001 0.010577 0.0 8035.2 9114.2 11787.0 12536.0 15190.0 12582.0 11368.0 9769.6 11112.0 11645.0 False True 9395.400657565951 10018.997542350608 12068.046782446427 11833.64856226036 12213.628542327382 11922.177770654875 10291.140742807283 9513.158351746839 11274.491978161346 13756.146318230716 0.6829965631518788 0.7283288001286125 0.8772839793404139 0.8602444528070691 0.8878670130268191 0.8666800639401949 0.7481121896158274 0.691556932564701 0.8195966891700993 1.0 13.747788745937026 -5.103265351955014 4.61851389802351 0.8321181233479182 0.6923597196570722 0.32607844168632083 0.07907615375021952 0.27226805642461394 9.20026197268662 0.021303671143545425 0.06349318546521264 7.883782748881097e-06 5.103265351955014 -0.13975840369084602 WTPKSPLDPDS(ph)GLLSCTLPNGFGGQSGPEGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WTPKSPLDPDSGLLSCTLPNGFGGQSGPEGER 32 1 Q9H4L4;A0A087X0R7 Q9H4L4 SENP3;SENP3-EIF4A1 Sentrin-specific protease 3 1 WT(0.033)PKS(0.462)PLDPDS(0.478)GLLS(0.024)CT(0.003)LPNGFGGQSGPEGER 69.08800000000001 0.00051329 0.0 15520.0 13697.0 13411.0 16288.0 17125.0 19192.0 19541.0 17336.0 19817.0 14528.0 True False 18147.22946602743 15056.747639680541 13730.76910150073 15375.436166408484 13769.479182841109 18185.537734414916 17689.935015411436 16880.948369010322 20106.78613491932 17161.81139641527 1.0574192343016888 0.8773402347741434 0.8000769140470096 0.895909867044692 0.8023325081941673 1.0596514152470806 1.030773186279537 0.9836344182489027 1.1716004604921362 1.0 14.066914214129712 -6.776341832940911 24.997916983387924 1.0469616727394058 0.8818090725471776 0.49871917727529536 0.08138064182580257 203.89975451645716 342026.7472439842 0.028540292029199343 0.025270211466709862 1.6736250481355025e-07 6.776341832940911 -0.16515260019222822 WVNPHKL ddPTM_PC-9_AZD4547_30min_R2 2 WVNPHKL 7 1 P11413;P11413-2;P11413-3 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ; 81.635 0.014968 17698100.0 152284.0 146361.0 203464.0 289420.0 238850.0 195018.0 173513.0 221630.0 167938.0 189686.0 False True 200707.1442960267 193669.33100464972 200765.93441898405 222698.6904944257 205689.80035110808 182823.49363097356 188955.32086077947 187382.17605074277 176814.85982777804 183045.1508759251 1.0964898186899994 1.0580413088130705 1.09681099694944 1.216632559938063 1.123710731296741 0.998789056995551 1.0322880445429583 1.0236937452539099 0.9659630915195881 1.0 17.481840029560182 -6.760153234235605 24.999013431324006 1.007386463828865 1.1192522977799453 0.656833362434406 0.04123313107121797 24.501261180469005 476238.17063248256 0.015430820675262939 0.014634206315550236 1.7371877801845305e-07 6.760153234235605 0.1118658339510803 WVNPHKL ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 WVNPHKL 7 1 P11413;P11413-2;P11413-3 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ; 81.635 0.014968 16981800.0 134312.0 124514.0 144000.0 160818.0 182702.0 155047.0 164882.0 135113.0 140153.0 127591.0 False True 157048.36881707978 136874.92703564186 147433.5061230411 151807.888838991 146902.85463728092 146916.06237535572 149263.18331769443 131566.42691405705 142202.4724815738 150722.23829019998 1.0419721110742761 0.9081269531845954 0.9781801796173782 1.0072029884979594 0.9746594550595431 0.9747470847167499 0.9903195773294164 0.8729065359335999 0.9434737308490452 1.0 17.20153276930239 WVNPHKL ddPTM_PC-9_Lapatinib_30min_R1 2 WVNPHKL 7 1 P11413;P11413-2;P11413-3 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 ; 81.635 0.014968 22049100.0 201754.0 161004.0 180269.0 166728.0 166111.0 163515.0 158095.0 139293.0 162329.0 130156.0 False True 198876.95096284806 160631.2051300565 165447.9786784633 178989.73330830305 156340.67756679148 156521.8446220821 166280.38553522385 145765.0612940968 144045.79861984903 152653.29117803136 1.3028015932582058 1.0522616570560601 1.0838153399883803 1.172524561554044 1.0241553022558794 1.025342090001447 1.0892682643920197 0.9548766369150785 0.9436141042767046 1.0 17.219899168567416 -1.5228787452803503 0.28422240195778753 0.9752852374696194 2.961282113343521 0.6096806948887082 0.06357294007460167 39.03518452089349 0.551938702905158 0.07116010317055894 38.694790065956184 0.02999999999999912 1.5228787452803503 1.9859968758739015 WYNHIK ddPTM_PC-9_AZD4547_30min_R2 1 WYNHIK 6 0 P24534;C9JZW3;F2Z2G2 P24534 EEF1B2 Elongation factor 1-beta 0 102.12 0.029813 2541100.0 39058.0 35680.0 45033.0 75833.0 55006.0 44065.0 39567.0 54608.0 43699.0 47776.0 False True 51477.63154313133 47212.86223957132 44435.83299596054 58350.87345817079 47369.366372673336 41309.60858407362 43088.38634856446 46169.58836700346 46008.839926723354 46103.37678188264 1.116569655768916 1.0240651669168988 0.963830332996836 1.2656529202672435 1.027459801844454 0.8960213213776385 0.9346036962198616 1.001436154783934 0.9979494591989099 1.0 15.492584802396307 -6.524035221093818 24.997767885363555 0.9638640315510053 1.0869601512181062 0.36657324816077275 0.07827046009890795 45.197205909202985 976923.4914035321 0.026324993016023254 0.0265414087324218 2.992021975086049e-07 6.524035221093818 0.12309611966710088 WYNHIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 WYNHIK 6 0 P24534;C9JZW3;F2Z2G2 P24534 EEF1B2 Elongation factor 1-beta 0 92.075 0.030024000000000002 4371500.0 58100.0 59551.0 60073.0 65508.0 81503.0 74406.0 73905.0 70648.0 69871.0 59856.0 False True 67935.18247269292 65462.829721151735 61505.36814812114 61837.79913980149 65533.072224181 70504.01837572297 66904.1833741356 68793.56485774358 70892.73119205453 70707.41898016464 0.9607928482264441 0.92582688868216 0.869857350688689 0.8745588515562799 0.9268203134746696 0.9971233484777781 0.9462116470819567 0.9729327678760562 1.0026208312304805 1.0 16.109573977389623 -6.622435131235319 4.894494812739361 0.9794293411362051 0.9057022473388321 0.6171707288747839 0.02857448663348775 0.1572189681417061 6.253571425992079 0.010286367491662854 0.010272161811624011 2.3854200691544435e-07 6.622435131235319 -0.07372709379737297 WYNHIK ddPTM_PC-9_Lapatinib_30min_R1 1 WYNHIK 6 0 P24534;C9JZW3;F2Z2G2 P24534 EEF1B2 Elongation factor 1-beta 0 102.12 0.029813 4384000.0 78718.0 71854.0 78089.0 76609.0 80969.0 71404.0 72933.0 79220.0 77729.0 71864.0 False True 77595.46688488661 71687.62647769671 71668.82385225689 82243.08142013244 76206.56261117876 68350.2173708537 76709.11387609028 82900.85040682855 68974.3414973433 84285.59664723896 0.9206254683068498 0.850532348696912 0.8503092663888099 0.9757667346693283 0.9041469200262836 0.810935914198013 0.9101094009827257 0.9835707843867323 0.8183407870507466 1.0 16.36299849326734 -11.439172963016246 2.6025360070017705 1.0648343421322113 0.8928936541714214 0.24718809736661873 0.05671461287558291 25079783.496563468 13917687.337527806 9918670.24131632 0.014053608205735571 3.6377013143115523e-12 11.439172963016246 -0.17194068796078987 Y(ph)AIS(ph)VARKIGARIY(ph)ALPDDLVEVK ddPTM_PC-9_AZD4547_30min_R2 1 YAISVARKIGARIYALPDDLVEVK 24 3 Q14651 Q14651 PLS1 Plastin-1 3 Y(1)AIS(1)VARKIGARIY(1)ALPDDLVEVK 46.353 0.044347000000000004 0.0 15189.0 9760.9 13892.0 19593.0 10775.0 16649.0 19946.0 17380.0 12727.0 8763.1 True False 20018.78604917358 12915.920040197085 13707.783003128456 15076.136558832439 9279.077240038456 15607.93539807651 21721.155359478016 14694.320352668481 13399.723237314545 8456.306536280046 2.3673202908725095 1.527371315690128 1.621013020793183 1.782827584850593 1.0972966980594283 1.8457154232895732 2.568633867077531 1.7376759332961167 1.5845834324744243 1.0 13.045811959201455 -8.665514904886615 2.6556310018373117 1.0012591573994718 1.8001733862608973 0.286897890684347 0.3897510251633811 0.8084851290926127 11.251139213691616 0.390750535577599 0.10500585172128002 2.1601558974495735e-09 8.665514904886615 0.7989142288614255 Y(ph)CEKS(ph)MIS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 YCEKSMISR 9 1 Q96FC9-4;Q96FC9-3;Q96FC9-2;A8MPP1;Q92771;Q96FC9 Q96FC9-4 DDX11;DDX11L8;DDX12P Probable ATP-dependent RNA helicase DDX11;Putative ATP-dependent RNA helicase DDX11-like protein 8;Putative ATP-dependent RNA helicase DDX12 3 Y(1)CEKS(1)MIS(1)R 47.971000000000004 0.043212 0.0 13478.0 12208.0 10853.0 8710.6 10322.0 8596.1 9619.8 9859.1 11408.0 10450.0 True False 13285.801248437509 12179.733126057286 9960.708233791514 9351.206581709786 9714.880253832798 8228.464841487812 10117.866173957102 10317.18977841408 10123.110908434335 12256.268576250257 1.084000498665821 0.9937554036355504 0.8127031626161494 0.7629733734645966 0.7926458361607653 0.6713678629262928 0.8255258206044153 0.8417888131471228 0.8259537432176155 1.0 13.5812321965936 -5.143374487271768 2.7723603177526557 0.8018962521699208 1.0756207925655268 0.5705191484322596 0.07812239910926647 0.18718482158631322 2.657801706611149 0.020270143198736518 0.07799802123599386 7.188288725943684e-06 5.143374487271768 0.273724540395606 Y(ph)DSSNQVK ddPTM_PC-9_AZD4547_30min_R2 1 YDSSNQVK 8 0 A0A087WZ12;A0A087WT34;A0A087X1H1;A0A0A0MTS6;K7EIE8;O95983-2;O95983 A0A087WZ12 MBD3 Methyl-CpG-binding domain protein 3 1 Y(0.925)DS(0.07)S(0.006)NQVK 95.741 0.0091832 25350000.0 99699.0 80352.0 112190.0 173580.0 142380.0 126010.0 111830.0 124470.0 123150.0 131550.0 True False 131401.20813197453 106324.21263099884 110702.28729635624 133563.81278426654 122612.99465769633 118130.57477996426 121782.65335658402 105236.0215360557 129659.45758429219 126944.47454070351 1.035107739879155 0.8375647149329608 0.8720528222822383 1.0521435711756058 0.9658789411774017 0.9305688586082322 0.9593379609250783 0.8289925332851947 1.0213871698899202 1.0 16.953838075202377 Y(ph)DSSNQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YDSSNQVK 8 0 A0A087WZ12;A0A087WT34;A0A087X1H1;A0A0A0MTS6;K7EIE8;O95983-2;O95983 A0A087WZ12 MBD3 Methyl-CpG-binding domain protein 3 1 Y(0.964)DS(0.035)SNQVK 86.794 0.017702000000000002 6389700.0 22762.0 23094.0 25139.0 32694.0 35975.0 35707.0 38649.0 38192.0 45832.0 33082.0 True False 26615.15703000749 25386.619697071073 25738.40910018841 30862.261175378142 28925.956998698337 33834.462061418984 34987.886925471386 37189.500467768936 46502.20629437464 39079.5047230321 0.6810515439905624 0.6496146733944937 0.6586165634033506 0.7897301000641648 0.7401822823422423 0.8657853343130557 0.8953001624109822 0.951636944514569 1.1899384760362088 1.0 15.254124562870249 -7.186250474823841 0.744834592295889 1.0831453532479227 0.6672711008196612 0.8508604807791983 0.06358556256486664 0.24070352083463437 0.2674720480321655 0.05115497419276543 0.03416381450994586 6.512526825186812e-08 7.186250474823841 -0.4158742524282615 Y(ph)EDMHRDLVTMVEQLAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YEDMHRDLVTMVEQLAR 17 1 Q9BR01-2;Q9BR01 Q9BR01-2 SULT4A1 Sulfotransferase 4A1 1 Y(1)EDMHRDLVTMVEQLAR 63.966 0.025036000000000003 0.0 2449.9 4507.3 3469.9 5931.1 7612.0 3807.1 4995.2 4694.3 4519.3 3583.5 True False 2864.6196822693673 4954.754956292038 3552.6355756690327 5598.799695885641 6120.483243199212 3607.4489739834835 4522.018493883793 4571.079599021984 4585.386212824386 4233.16018302961 0.6767094932418081 1.170462430445047 0.8392395803757333 1.3226052059949838 1.4458425806176018 0.8521881568397645 1.0682370376656645 1.079826749138165 1.0832064024429837 1.0 12.047519366016287 -4.755572496017667 24.97106391927491 1.0997738748826817 0.6767087972458863 0.33371412968719294 0.17754234531247695 232.1317997805385 987916.3096177375 0.045165749739516946 0.39583057972006364 1.7556078091992013e-05 4.755572496017667 -0.42306507763679546 Y(ph)EEEIRR ddPTM_PC-9_AZD4547_30min_R2 1 YEEEIRR 7 1 J3KNA1;Q12840 J3KNA1 KIF5A Kinesin-like protein;Kinesin heavy chain isoform 5A 1 Y(1)EEEIRR 53.553999999999995 0.044519 0.0 2655.4 2511.0 5915.6 13199.0 5728.7 5657.2 1543.2 2534.7 2739.9 6540.1 True False 3499.761964248836 3322.6316447187096 5837.155278815623 10156.174472517198 4933.368889559937 5303.454389692982 1680.5418104254725 2143.0203566115524 2884.7255203832874 6311.133089651509 0.5545378166699519 0.5264714905421493 0.9248981436292197 1.6092473931773803 0.7816930524962753 0.8403331564008945 0.2662821060105816 0.3395619021448788 0.45708519839542433 1.0 12.62368333203576 -7.150157318286187 5.961230424809756 0.4622343957795291 0.8936379654282353 0.20799143524135166 0.33452793230770567 0.34508607877094893 15.983622954681493 0.13700089647743263 0.10574091622009099 7.076893854363885e-08 7.150157318286187 0.4314035696487062 Y(ph)EGY(ph)LRRKGLFS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 YEGYLRRKGLFSR 13 3 A0A2R8YEJ5;Q96M69 A0A2R8YEJ5 LRGUK Leucine-rich repeat and guanylate kinase domain-containing protein 3 Y(1)EGY(1)LRRKGLFS(1)R 41.401 0.045742000000000005 30624000.0 41785.0 60119.0 63092.0 63632.0 58028.0 64491.0 53176.0 67746.0 60383.0 62166.0 True False 55071.760818007686 79551.29105887859 62255.35885641957 48962.62550459987 49971.81383619042 60458.36757507068 57908.56098443814 57277.412348209364 63574.72210566229 59989.58726185777 0.9180219990115367 1.3260849872434182 1.0377694146264347 0.8161854038247568 0.8330081288617768 1.0078143613685264 0.9653102084477454 0.9547892386422061 1.059762618938437 1.0 15.872424485114486 -5.522022572764377 24.98849835919704 0.9432879351286366 1.1370219281442435 0.2675089960547199 0.11557942241971718 32.707612360272556 954618.3958351928 0.030472781249814358 0.053629302298391926 3.0059200637361452e-06 5.522022572764377 0.1937339930156069 Y(ph)FDSGDYNMAK ddPTM_PC-9_AZD4547_30min_R2 1 YFDSGDYNMAK 11 0 A6NMQ3;Q5T5H1;O43768-2;O43768;O43768-9;O43768-3;O43768-4;O43768-6;O43768-5;O43768-7;P56211;H3BQ52;H3BMD8;P56211-2;H3BTD3 A6NMQ3;P56211;P56211-2 ENSA;ARPP19 Alpha-endosulfine;cAMP-regulated phosphoprotein 19 1 Y(0.925)FDS(0.075)GDYNMAK 78.149 0.027131 13170000.0 43705.0 45407.0 67702.0 69425.0 53630.0 52751.0 59311.0 56190.0 37591.0 50662.0 True False 57602.280879526785 60083.924767719065 66804.22724429898 53420.13885555766 46184.40022118445 49452.47163096485 64589.564099368334 47507.126617746966 39577.98351645249 48888.33880031267 1.1782417298899588 1.2290031987614762 1.3664654779366676 1.0926969532295914 0.9446915431065757 1.0115392104640009 1.3211650402601784 0.9717476147388164 0.809558771839459 1.0 15.577202763720043 -6.269703123914867 0.4616389237104632 0.9572476787305407 1.2973901629676723 0.3424504152091553 0.13687663119373725 1.9338003190706556 0.7713818709985479 0.1320919196030038 0.30935399859915935 5.373990273823571e-07 6.269703123914867 0.34014248423713156 Y(ph)FDSGDYNMAK ddPTM_PC-9_Lapatinib_30min_R1 1 YFDSGDYNMAK 11 0 A6NMQ3;Q5T5H1;O43768-2;O43768;O43768-9;O43768-3;O43768-4;O43768-6;O43768-5;O43768-7;P56211;H3BQ52;H3BMD8;P56211-2;H3BTD3 A6NMQ3;P56211;P56211-2 ENSA;ARPP19 Alpha-endosulfine;cAMP-regulated phosphoprotein 19 1 Y(0.992)FDS(0.008)GDYNMAK 85.67 0.016437 22775000.0 35392.0 34605.0 24763.0 22548.0 22374.0 26038.0 30598.0 37213.0 28859.0 15546.0 True False 34887.303589902105 34524.87424862485 22727.081727944285 24206.255137923017 21058.005308976448 24924.41543754259 32182.214722836172 38942.05183273554 25608.595521257554 18233.10538625708 1.913404373574118 1.8935268303032702 1.2464734474180394 1.3275991459012848 1.15493246284029 1.3669868576709363 1.765042983138408 2.135788227390355 1.4045109145565315 1.0 14.154272675639243 -5.239281081392847 22.215710162662873 1.4626554599351553 1.9034663629544735 0.27593164623625455 0.3051221404524245 298.3908189413878 299157.36172752065 0.08440295461424856 0.22262666131854952 5.763932929368614e-06 5.239281081392847 0.44081090301931813 Y(ph)FSQKQDVVLIKNLLISVQS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YFSQKQDVVLIKNLLISVQSR 21 2 E9PHM6;F6QMI7;F8W9J4;Q03001-8;Q03001-14;Q03001;A0A494C073;A0A0U1RQJ2 E9PHM6 DST Dystonin 2 Y(0.845)FS(0.155)QKQDVVLIKNLLIS(0.034)VQS(0.966)R 51.398 0.033363 24984000.0 23639.0 14691.0 49139.0 24660.0 64833.0 62285.0 34790.0 41746.0 51413.0 30449.0 True False 27640.61580846793 16149.42539056339 50310.66012069527 23278.380148798693 52129.43905758468 59018.66495352399 31494.43934221194 40650.21173354319 52164.81786115994 35969.162665848606 0.7684531348490822 0.4489797424696982 1.3987164668824328 0.6471760370140798 1.4492814175816124 1.640812868005961 0.8755955659794868 1.1301406182618499 1.4502650046587966 1.0 15.13447295459437 -5.258956846716839 24.94155321635692 1.1971060904277775 0.6087164123916143 0.3918001334482034 0.29417057938799857 206.59035899805875 2075543.6281561733 0.07578730576378158 0.18224221276056723 5.5086242963923526e-06 5.258956846716839 -0.5883896780361632 Y(ph)FVQGMGYMPSASMTR ddPTM_PC-9_AZD4547_30min_R2 1 YFVQGMGYMPSASMTR 16 0 Q92597;E5RJY1;E7ESM1;Q92597-3;Q92597-2 Q92597 NDRG1 Protein NDRG1 1 Y(0.751)FVQGMGY(0.106)MPS(0.067)AS(0.01)MT(0.067)R 51.998000000000005 0.033401 5528100.0 13954.0 18983.0 24865.0 35607.0 24571.0 19939.0 20577.0 22061.0 20666.0 25129.0 True False 18391.081738769386 25118.88351720242 24535.273853497616 27398.35627266609 21159.740776332714 18692.211177983518 22408.31313706905 18651.97936134749 21758.36256952481 24249.241358672316 0.7584188497588663 1.035862654244195 1.0117955234390459 1.1298644715277886 0.8725939283360427 0.7708369470824116 0.9240830591615646 0.7691778511939689 0.8972801353945579 1.0 14.565651992614093 -6.486982862085869 24.31774816008453 0.8567125184119081 0.9911213628151286 0.1951326389681336 0.1084352660712053 585.7663926710338 396828.69870436616 0.03284935213077576 0.037231051961888195 3.2584955926251273e-07 6.486982862085869 0.13440884440322054 Y(ph)IRLHPT(ph)HYS(ph)IRS(ph)T(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 1 YIRLHPTHYSIRSTLR 16 2 A0A2R8Y707;P00451-2;P00451 A0A2R8Y707 F8 Coagulation factor VIII;Factor VIIIa heavy chain, 200 kDa isoform;Factor VIIIa heavy chain, 92 kDa isoform;Factor VIII B chain;Factor VIIIa light chain 5 Y(1)IRLHPT(1)HY(0.594)S(0.658)IRS(0.884)T(0.863)LR 57.045 0.022784 5899600.0 10612.0 7569.1 9737.1 9650.4 10118.0 7927.4 6167.6 8021.0 11208.0 6894.8 True False 10460.670933997544 7551.574213994115 8936.553224292955 10360.12260879068 9522.87913275336 7588.363581671984 6486.928149701432 8393.684942100122 9945.637014527692 8086.556993256487 1.2935877336573365 0.9338429470405634 1.10511225379915 1.2811537243143352 1.1776185020021062 0.9383923946866443 0.8021866605418089 1.0379800635919285 1.2298975970640562 1.0 12.981309862960508 -6.755839171953701 24.993586098137744 0.9915960498509508 1.1496697059721817 0.2460884396452523 0.1360383916999301 216.38758952488521 965731.6792474266 0.04811514932127116 0.04683702035738093 1.754530119604507e-07 6.755839171953701 0.1580736561212308 Y(ph)IYFLIK ddPTM_PC-9_Lapatinib_30min_R1 1 YIYFLIK 7 0 Q7L1T6 Q7L1T6 CYB5R4 Cytochrome b5 reductase 4 1 Y(0.5)IY(0.5)FLIK 76.805 0.044541000000000004 2228500.0 24511.0 35607.0 20838.0 23940.0 24847.0 24798.0 22999.0 26451.0 26835.0 23283.0 True False 24161.46864523312 35524.554179187566 19124.780077006148 25700.627461498883 23385.548311081526 23737.4473469614 24189.775685028715 27680.010024122956 23812.55971492243 27307.435527352605 0.8847944956615089 1.300911399886095 0.7003506447117575 0.9411585879514663 0.8563802444084248 0.8692668091511079 0.8858311012324437 1.0136437014159443 0.872017428772119 1.0 14.737006214865046 -5.264248707584746 24.998503376916524 0.8922223627148678 1.0928529355946108 0.2941126168371795 0.1242602347549838 260.81079360679865 2320819.575365769 0.029950202638964547 0.06712570884345202 5.441909215710105e-06 5.264248707584746 0.20063057287974306 Y(ph)KT(ph)ETLT(ph)AFLSYPT(ph)MDATK ddPTM_PC-9_AZD4547_30min_R2 1 YKTETLTAFLSYPTMDATK 19 1 Q8NDH2 Q8NDH2 CCDC168 Coiled-coil domain-containing protein 168 4 Y(0.971)KT(0.878)ET(0.351)LT(0.592)AFLS(0.202)Y(0.187)PT(0.674)MDAT(0.145)K 40.961999999999996 0.027235000000000002 14970000.0 6390.2 9277.3 11165.0 17481.0 11137.0 16599.0 11372.0 15275.0 11370.0 11990.0 True False 8422.150675582925 12276.005797510508 11016.9448049186 13451.025528757713 9590.819788613306 15561.06190598066 12384.08596951689 12914.599734580612 11970.994987684948 11570.233749471976 0.7279153436262498 1.0609989446471417 0.952179968310612 1.1625543459198973 0.8289218693659491 1.3449219992371209 1.0703401709651765 1.1161917740140719 1.0346372637658476 1.0 13.498130390563352 -4.300927535319966 1.5197857837078224 1.0768323218204812 9.443587846096018e-25 0.3695626488991067 0.12935846722065306 4.429763725836144 3.533581070902443 0.03452460580195474 10.27707148776515 5.0011797574646416e-05 4.300927535319966 -1.0768323218204812 Y(ph)LGS(ph)LT(ph)T(ph)PT(ph)CDEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YLGSLTTPTCDEK 13 0 K7EIH9;K7EKY5;P22748 K7EIH9 CA4 Carbonic anhydrase 4 5 Y(1)LGS(1)LT(1)T(1)PT(1)CDEK 41.117 0.045768 0.0 3330.4 3505.6 5734.8 4129.2 5000.3 5517.5 4486.6 4473.4 4406.3 3549.3 True False 3894.1709416016593 3853.612800296714 5871.5393813501105 3897.854311047022 4020.5271099538913 5228.152586996366 4061.5967678289185 4355.9779899590885 4470.7338015993855 4192.759993756659 0.9287846066553721 0.919111231273681 1.400399591222317 0.9296631137606792 0.9589213587090041 1.246947737237878 0.9687167340551205 1.0389285331012206 1.0662985260917988 1.0 12.033684532989193 -10.859355600344237 5.3886454423334795 0.999985648298175 1.054000076343563 0.009933376068713251 0.14941440114377125 2.5348104542445052e-05 3.121104024805094e-06 0.14234541263616118 0.034514661591634195 1.3824339784172253e-11 10.859355600344237 0.05401442804538803 Y(ph)LKRSIITS(ph)REQGIR ddPTM_PC-9_Lapatinib_30min_R1 1 YLKRSIITSREQGIR 15 3 Q8NG66-4 Q8NG66-4 2 Y(0.99)LKRS(0.012)IIT(0.002)S(0.996)REQGIR 56.817 0.025447 7363900.0 64028.0 48732.0 21904.0 40056.0 33932.0 35118.0 27491.0 31783.0 20957.0 33729.0 True False 63114.948978702865 48619.164048085135 20103.137671885146 43001.85186289887 31936.186472878737 33616.08500405639 28914.349465503932 33259.75420954597 18596.6019730065 39559.01270893257 1.5954631993242663 1.2290287527096637 0.5081809755920876 1.0870304620415587 0.8073049423113492 0.8497705757066519 0.7309168628208703 0.8407630001856896 0.47009772740883704 1.0 15.271718800143416 -5.017586229766029 4.110836894672715 0.7934166772544006 1.5472452999461195 0.6739058370337158 0.18211420488305788 0.1065206081927796 4.172379606515823 0.04450036283820843 0.16680108944341637 9.603151275685061e-06 5.017586229766029 0.7538286226917189 Y(ph)LLGDAPVSPSSQK ddPTM_PC-9_AZD4547_30min_R2 3 YLLGDAPVSPSSQK 14 0 Q9NYB0;A0A590UJT3;H3BMI8 Q9NYB0 TERF2IP Telomeric repeat-binding factor 2-interacting protein 1 1 Y(0.993)LLGDAPVS(0.007)PSSQK;Y(0.861)LLGDAPVS(0.137)PS(0.002)SQK;Y(0.977)LLGDAPVS(0.022)PS(0.001)SQK 139.86 8.1562e-05 173773000.0 746290.0 710710.0 975140.0 1174560.0 1128460.0 987130.0 896320.0 983380.0 917090.0 991230.0 True False 983594.6962036828 940433.1088084579 962209.0064548427 903783.3387711034 971792.8076374765 925404.6050515521 976090.7435980792 831421.2168243474 965565.5051236576 956527.3394069286 1.0282975255192774 0.9831743119768541 1.005939889863929 0.9448588676320242 1.0159592597112936 0.9674627864011984 1.0204525300900238 0.8692080012473556 1.0094489361091685 1.0 19.867446678620453 Y(ph)LLGDAPVSPSSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YLLGDAPVSPSSQK 14 0 Q9NYB0;A0A590UJT3;H3BMI8 Q9NYB0 TERF2IP Telomeric repeat-binding factor 2-interacting protein 1 1 Y(0.924)LLGDAPVS(0.069)PS(0.006)S(0.001)QK;Y(0.971)LLGDAPVS(0.026)PS(0.002)S(0.001)QK 183.85 1.0164e-05 83616000.0 168796.0 174533.0 176562.0 185355.0 228056.0 183659.0 196620.0 197034.0 187143.0 134693.0 True False 197369.82892703387 191859.4827915863 180771.90769511368 174970.1602790182 183370.0639136937 174027.59872680868 177994.73019447294 191862.06627477962 189879.61233522766 159111.7746707988 1.2404476622512113 1.2058157429803187 1.1361315532375247 1.0996682089746677 1.1524606792494467 1.093744313309751 1.1186772981618918 1.205831979887981 1.1933724749666537 1.0 17.279681077111455 Y(ph)LREADFARVAHLT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 YLREADFARVAHLTR 15 2 Q8WUY1 Q8WUY1 THEM6 Protein THEM6 2 Y(1)LREADFARVAHLT(1)R 92.611 0.0052242 0.0 9994.8 8872.2 13845.0 18361.0 13653.0 7871.4 8765.3 6682.6 7278.4 12586.0 True False 13172.938495245253 11739.965144672777 13661.406253837711 14128.15512462218 11757.51661793457 7379.200113665652 9545.39471936391 5649.957720871255 7663.121364851899 12145.367970880248 1.08460596062867 0.9666207868563994 1.1248244010879143 1.1632545970196924 0.968065903488837 0.6075732025046942 0.7859288201271434 0.46519444568642154 0.6309501188621875 1.0 13.568118579833817 -6.639843094381002 4.285554890230473 0.6705626058754068 1.0780648202820846 0.6345326688392763 0.13902409276045555 0.13094190183971527 4.260301508598473 0.045825793923084494 0.04558576694550948 2.2916954665266075e-07 6.639843094381002 0.4075022144066778 Y(ph)LS(ph)HDVVVMT(ph)VK ddPTM_PC-9_Lapatinib_30min_R1 1 YLSHDVVVMTVK 12 0 H0YF42;A0A0C4DG39;Q8IZM9;Q8IZM9-2 H0YF42 SLC38A6 Probable sodium-coupled neutral amino acid transporter 6 3 Y(1)LS(1)HDVVVMT(1)VK 45.723 0.0424 1434600.0 14741.0 11928.0 15207.0 13135.0 13909.0 13614.0 12281.0 13486.0 11726.0 13042.0 True False 14530.79063683168 11900.381448854141 13956.73916071755 14100.99171707551 13090.899966146128 13031.76095578404 12916.850088605503 14112.608793063479 10405.294399745873 15296.292322627369 0.9499550826010755 0.7779912411356212 0.9124262838564967 0.9218568408382413 0.8558217697488124 0.8519555380428059 0.8444432033701379 0.9226163108943138 0.680249447400637 1.0 13.900894379134973 -6.4732154046489265 24.30891960652908 0.8540349436090007 0.8846740447553438 0.027157033154814436 0.08608281322494789 1264.1436648009067 618764.9138562182 0.025328385076999537 0.02871920746228023 3.363447052168671e-07 6.4732154046489265 0.03063910114634316 Y(ph)NHDLPAR ddPTM_PC-9_Lapatinib_30min_R1 1 YNHDLPAR 8 0 F5H116;Q7Z3Z4 F5H116 PIWIL4 Piwi-like protein 4 1 Y(1)NHDLPAR 45.972 0.042088 2355700.0 4740.0 4450.7 4278.0 3874.5 6049.5 5671.7 4909.9 4313.4 5835.6 4164.3 True False 4672.40673079046 4440.394677600194 3926.279353557554 4159.4436549531065 5693.680303774608 5429.134612378455 5164.11059767479 4513.816310840875 5178.333276407728 4884.093706419043 0.9566578799767154 0.9091542760050434 0.8038910777648148 0.8516306002660131 1.165759841235549 1.1115950959833303 1.0573324158149808 0.9241870820186104 1.0602444563260474 1.0 12.25387516485824 -6.242307345923451 24.98628859836906 1.052523566295539 0.8769319032091508 0.593928933593849 0.06999518375292853 626.8792315487002 818699.7123006223 0.02251167981305983 0.02901868200988082 5.723908122830306e-07 6.242307345923451 -0.17559166308638818 Y(ph)PPIVAS(ph)MT(ph)ADS(ph)K ddPTM_PC-9_Lapatinib_30min_R1 1 YPPIVASMTADSK 13 0 Q9NP92 Q9NP92 MRPS30 28S ribosomal protein S30, mitochondrial 4 Y(1)PPIVAS(1)MT(1)ADS(1)K 56.783 0.042707999999999996 0.0 3354.4 3491.8 975.83 2748.9 2852.8 3280.4 2374.5 2733.6 1103.4 2126.0 True False 3306.565640878379 3483.7149516355526 895.6010242127313 2951.0632760615827 2685.003912820597 3140.1049389858913 2497.439991482268 2860.6130354974302 979.123472682893 2493.476267283069 1.3260866703500913 1.3971317863921213 0.3591776813615284 1.183513681193809 1.0768114972861642 1.2593281837839183 1.0015896378286038 1.147238926245887 0.39267406934246113 1.0 11.283942756269099 -8.235868177411671 24.654709043240658 0.6963368842882692 1.0843395801324893 0.2154829907083191 0.30296533684473875 859.6489364067509 828841.2090877265 0.2025256551396933 0.07648014223534855 5.8094072528482865e-09 8.235868177411671 0.3880026958442201 Y(ph)PPNAPFY(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YPPNAPFYK 9 0 Q9P225;Q9P225-2 Q9P225 DNAH2 Dynein heavy chain 2, axonemal 2 Y(1)PPNAPFY(1)K 41.448 0.04635 0.0 32186.0 30192.0 40767.0 38963.0 51351.0 50180.0 45046.0 50786.0 42229.0 34210.0 True False 37634.4540975231 33189.26222802329 41739.03988970848 36780.02942975036 41289.14017623787 47548.47246315861 40778.91677520207 49452.921312214945 42846.51923558099 40412.00219378898 0.9312692283112671 0.8212724048877793 1.0328377121617462 0.9101263840721846 1.0217048880241746 1.176592840788929 1.0090793467656864 1.2237186634572508 1.060242425755539 1.0 15.30249621049406 -6.470676881044992 3.838889727624766 1.1030486415780087 0.9254144762748905 0.49598625082267045 0.08024190285896621 0.18197131702785546 5.459817986145296 0.02515374290344081 0.02771247719198089 3.383164530401732e-07 6.470676881044992 -0.17763416530311826 Y(ph)PVKYRS(ph)GK ddPTM_PC-9_AZD4547_30min_R2 1 YPVKYRSGK 9 2 Q8WWU7-2;Q8WWU7 Q8WWU7-2 ITLN2 Intelectin-2 2 Y(1)PVKY(0.005)RS(0.995)GK 87.806 0.017374 0.0 30545.0 36490.0 36999.0 48930.0 46021.0 56340.0 60300.0 53431.0 52880.0 49769.0 True False 40257.6746245314 48284.678899158025 36508.36908528287 37649.94446096419 39631.77853028396 52817.050893605076 65666.58318342136 45174.46667223418 55675.12884334038 48026.6024585046 0.8382369887462761 1.0053736143604246 0.7601697229535739 0.7839393697168994 0.8252047095050323 1.0997457281980223 1.3672960364031133 0.9406134175588479 1.1592560371399199 1.0 15.551546131292799 -6.786420704861479 6.622946963186791 1.1270925714603093 0.8434680467175019 0.5537061961615917 0.12132974723302946 0.12930566688001735 19.576631383147785 0.04261083844698145 0.038552069685652175 1.6352316906971082e-07 6.786420704861479 -0.2836245247428074 Y(ph)PVVMSKAAY(ph)MPK ddPTM_PC-9_AZD4547_30min_R2 1 YPVVMSKAAYMPK 13 1 P0DN81 P0DN81 2 Y(0.996)PVVMS(0.189)KAAY(0.815)MPK 53.251999999999995 0.030866 3711000.0 26549.0 21868.0 24787.0 32727.0 33812.0 29371.0 30820.0 26218.0 30191.0 22652.0 True False 34991.029746494816 28936.403347952517 24458.30818446191 25182.295777109637 29117.787437603754 27534.426726944883 33562.920293748735 22166.610529704383 31786.83462385192 21858.960374732185 1.6007636752451693 1.3237776569374948 1.118914521329863 1.1520353825344345 1.3320755854090112 1.2596402690209019 1.535430766988613 1.0140743269441042 1.4541787019567425 1.0 14.415937166749346 -11.672368927762644 2.446226512399854 0.30990715801834634 1.2973123877577508 0.21540555211695445 0.17603214976820206 14813782.779958313 6003429.11254969 56186945.50835691 0.04338951888317009 2.1263319859692104e-12 11.672368927762644 0.9874052297394045 Y(ph)PWGPLK ddPTM_PC-9_Lapatinib_30min_R1 1 YPWGPLK 7 0 D6RDL8;C9JK69;P17342-3;P17342-2;P17342 D6RDL8 NPR3 Atrial natriuretic peptide receptor 3 1 Y(1)PWGPLK 80.999 0.035647000000000005 3581800.0 50745.0 52707.0 42638.0 44530.0 48448.0 43919.0 48822.0 44688.0 48079.0 37741.0 True False 50021.36699450671 52584.96017980844 39132.46822743965 47804.88474772536 45598.38389243283 42040.686750189445 51349.76427211931 46764.36762156469 42663.83672568496 44264.48156327857 1.1300565425802707 1.187971898069907 0.8840602407485013 1.0799829357401505 1.0301348232724103 0.9497611914891608 1.160066998609527 1.0564761174196153 0.9638390695866301 1.0 15.433861903932945 -5.222164972333941 24.999737087892267 1.0231923117002906 1.1590142901207425 0.3772154558755326 0.07321443549669013 577.125929534343 367362.1214584287 0.018327300522059102 0.04848840888710808 5.995632811839229e-06 5.222164972333941 0.13582197842045196 Y(ph)QCIS(ph)KS(ph)FVT(ph)T(ph)GIRDK ddPTM_PC-9_Lapatinib_30min_R1 1 YQCISKSFVTTGIRDK 16 2 A0A2U3TZV8;Q4KWH8-2;Q4KWH8 A0A2U3TZV8 PLCH1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 5 Y(1)QCIS(1)KS(1)FVT(1)T(1)GIRDK 50.358000000000004 0.031731 4109400.0 5709.9 10293.0 15935.0 16657.0 16712.0 18430.0 13798.0 13674.0 23667.0 15811.0 True False 5628.475778932583 10269.167190900038 14624.885810878828 17882.011346123083 15729.03301705616 17641.791862428363 14512.392925867496 14309.343959391224 21001.37323544138 18543.91028316679 0.3035215169284886 0.5537757158058438 0.7886624550893426 0.9643063988696846 0.8482047624731105 0.9513523088192826 0.7825961571352672 0.7716465265894061 1.1325212921519225 1.0 14.178657871156199 -5.035657066211217 1.5702247931489195 0.9061882221147299 0.22515218541380705 0.793771053921778 0.10257763411598907 0.28867418797991323 0.9646201808349437 0.029250101357523824 0.2620710957450187 9.211766772778831e-06 5.035657066211217 -0.6810360367009229 down Y(ph)QFS(ph)GS(ph)S(ph)KDS(ph)CLNVK ddPTM_PC-9_Lapatinib_30min_R1 1 YQFSGSSKDSCLNVK 15 1 B4DHS6;O00534-4;O00534-3;O00534-2;O00534 B4DHS6 VWA5A von Willebrand factor A domain-containing protein 5A 5 Y(1)QFS(1)GS(1)S(1)KDS(1)CLNVK 47.397 0.029015 6981000.0 33312.0 43785.0 34845.0 37898.0 39784.0 31734.0 28421.0 29160.0 34002.0 29718.0 True False 32836.964771327366 43683.61852264238 31980.17860558972 40685.1453440219 37443.98333835344 30376.810795567097 29892.50031497897 30514.880053813693 30172.336703066612 34854.71670325409 0.9421096447546699 1.253305797736236 0.9175280028198881 1.1672780384476191 1.0742874101414692 0.8715265441457761 0.8576314238752129 0.8754878231721441 0.8656600757925448 1.0 15.089066281093563 -6.758488843151818 24.43593055286597 0.8840022813451867 1.0778688478988883 0.44228899302663705 0.0988130428012975 47.883928679573664 396568.2280727663 0.030905034730113138 0.02961421598525823 1.7438581558954764e-07 6.758488843151818 0.1938665665537016 Y(ph)QT(ph)MS(ph)ILPMELYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YQTMSILPMELYK 13 0 A0A1B0GW70;A0A2R8YDS2;A0A0A0MQZ2;B7ZCA0;A0A2R8Y6T2;Q96PV0-3;Q96PV0-2;Q96PV0-4;Q96PV0 A0A1B0GW70 SYNGAP1 Ras/Rap GTPase-activating protein SynGAP 3 Y(0.999)QT(0.998)MS(0.993)ILPMELY(0.01)K 57.034 0.035477999999999996 0.0 1126.2 2535.9 1961.5 2107.1 942.99 1107.1 1282.5 976.71 503.8 661.14 True False 1316.8434165360884 2787.647392820753 2008.2695990301759 1989.0460183103703 758.2178788103556 1049.0417270618357 1161.012315504077 951.072397409787 511.1671219040395 780.9994484186393 1.6861003156947436 3.5693333695243403 2.5714097533570635 2.546795676152874 0.9708302359823536 1.3432041843127112 1.4865725166066177 1.2177632126828128 0.6545038193548615 1.0 9.609177719238042 -6.230369127082268 6.483958971603211 1.1526178143644148 2.6696112310623894 0.6988412436419317 0.47497032450929716 0.10807591746911795 15.607621361467041 0.1379756189585786 0.17539603154823666 5.88343382374388e-07 6.230369127082268 1.5169934166979746 Y(ph)RSPEPDPYLSYR ddPTM_PC-9_AZD4547_30min_R2 1 YRSPEPDPYLSYR 13 1 H3BUL5;H3BVF8;H3BQG1;P49761-3;P49761-1;P49761;H3BRT8;H3BQR7;H3BV35;H3BRK0;P49761-2 H3BUL5 CLK3 Dual specificity protein kinase CLK3 1 Y(0.861)RS(0.139)PEPDPYLSYR 121.36 0.0010649000000000001 31181000.0 11810.0 13455.0 15767.0 26959.0 19743.0 21218.0 13561.0 24013.0 21232.0 14340.0 True False 15565.334336739745 17804.065623134324 15557.919278025207 20744.019062397976 17002.025238986476 19891.23510579539 14767.902728861995 20302.342613845125 22354.280174012903 13837.960964756301 1.1248286056293166 1.2866104817378252 1.1242927565448004 1.499066164099654 1.2286510478161259 1.437439746828025 1.0672022248418065 1.4671484234962695 1.6154316543417553 1.0 13.756343755851033 -5.73564271778268 24.995701229184217 1.3393858995986694 1.1893805967441873 0.12089477614436939 0.1862855219305971 493.1615227206147 477845.50053788075 0.04890825342874347 0.08467395964994702 1.8380498349660715e-06 5.73564271778268 -0.1500053028544821 Y(ph)RSPEPDPYLSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YRSPEPDPYLSYR 13 1 H3BUL5;H3BVF8;H3BQG1;P49761-3;P49761-1;P49761;H3BRT8;H3BQR7;H3BV35;H3BRK0;P49761-2 H3BUL5 CLK3 Dual specificity protein kinase CLK3 1 Y(0.727)RS(0.272)PEPDPYLS(0.001)YR 89.561 0.032448000000000005 17275000.0 20054.0 16871.0 20451.0 22613.0 18462.0 25444.0 22922.0 19344.0 16972.0 19124.0 True False 23448.746115445498 18545.8413834453 20938.629400849415 21346.066922335165 14844.50363057591 24109.671848397946 20750.662219091177 18836.240496662183 17220.183392130522 22591.02981449931 1.0379671182761085 0.8209382899199336 0.926855905763563 0.944891273112078 0.6570972528684129 1.0672232318034456 0.9185354713565579 0.8337929103423501 0.7622575656590171 1.0 14.463462417186493 -4.747832065597053 24.74454423696526 0.8794741204394193 1.0379675643343913 0.1484836584080198 0.11248593782342864 1194.804298784518 2172576.5303763486 0.027229828274092323 0.5240855010659865 1.787178513257175e-05 4.747832065597053 0.158493443894972 Y(ph)RSQSGEDESMNQPGPIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YRSQSGEDESMNQPGPIK 18 1 A0A0C4DG33;O43933-2;O43933 A0A0C4DG33 PEX1 Peroxisome biogenesis factor 1 1 Y(0.327)RS(0.306)QS(0.246)GEDES(0.121)MNQPGPIK 57.525 0.03356 0.0 12922.0 16105.0 13861.0 18703.0 21179.0 19256.0 22615.0 16719.0 21020.0 15835.0 True False 15109.439378866386 17703.79796576295 14191.498808135233 17655.13154594412 17029.126984723596 18246.18146174935 20472.743481578713 16280.143965244783 21327.377734066922 18705.760150208964 0.8077426021469433 0.9464356339223766 0.7586699869011577 0.943833952973405 0.9103680817020078 0.9754311674709205 1.0944619901667032 0.870327847385711 1.1401502832713628 1.0 14.19119497375435 -6.520034433074589 1.2652405929797432 1.0189258307111724 0.8525499816246217 0.44505338351699786 0.08319101345751569 0.4238816216855146 1.4131203382453938 0.03458254308513392 0.038991488486376784 3.019712292767062e-07 6.520034433074589 -0.16637584908655068 Y(ph)RTASQGPQTDSVIQNSENIK ddPTM_PC-9_Lapatinib_30min_R1 1 YRTASQGPQTDSVIQNSENIK 21 1 Q9NZN5-2;Q9NZN5;E9PMR6 Q9NZN5-2 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 Y(0.569)RT(0.161)AS(0.261)QGPQT(0.009)DSVIQNSENIK 85.177 0.0008212 0.0 9664.2 3698.6 4710.2 4727.0 9374.6 11483.0 8293.5 9896.5 16964.0 7045.5 True False 9526.386735802773 3690.0361189413074 4322.945537897798 5074.639348809742 8823.204459172732 10991.8988581804 8722.896849592844 10356.327518949487 15053.335681160588 8263.305287461366 1.1528542640507293 0.44655691525042907 0.5231496825437856 0.6141173746188386 1.0677572898778107 1.3302060707909906 1.0556183689387413 1.2532911660257846 1.8217087663458746 1.0 13.012503253716938 -6.4332076804484055 3.0673308002765385 1.2912246168301222 0.6551497270918383 0.5245369322254021 0.27190911282091557 0.20681393376235896 3.7542269870366916 0.09073737646155151 0.10200850935330748 3.6880119496139003e-07 6.4332076804484055 -0.636074889738284 Y(ph)S(ph)PEY(ph)VS(ph)MCDSLAK ddPTM_PC-9_Lapatinib_30min_R1 1 YSPEYVSMCDSLAK 14 0 A0A3B3IS08 A0A3B3IS08 4 Y(1)S(1)PEY(0.973)VS(0.977)MCDS(0.05)LAK 59.708999999999996 0.044031 11206000.0 28317.0 56693.0 41761.0 38862.0 51446.0 38449.0 51169.0 56626.0 38812.0 45394.0 True False 27913.194387298197 56561.730841707555 38327.57178212174 41720.041119831665 48420.04742672759 36804.62589899667 53818.280448160156 59257.0506833763 34440.583851521136 53240.292416297074 0.5242870224873869 1.0623858035834863 0.7198978450837643 0.783617805732806 0.9094624621540587 0.6912927076210164 1.0108562144502076 1.1130113677819973 0.6468894569966473 1.0 15.700230874660695 -7.272734118431694 24.496138629573828 0.9521068754287448 0.7976452182108752 0.16740187381324956 0.1731071461155926 1075.0552726512121 2331579.261895588 0.06823553569745362 0.046483745345295695 5.3366151104562e-08 7.272734118431694 -0.15446165721786964 Y(ph)S(ph)PIYSPDPY(ph)Y(ph)ASESEY(ph)WTYHGSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YSPIYSPDPYYASESEYWTYHGSPK 25 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 5 Y(0.958)S(0.961)PIY(0.119)S(0.122)PDPY(0.666)Y(0.498)AS(0.378)ES(0.268)EY(0.394)WT(0.33)Y(0.268)HGS(0.038)PK;Y(0.978)S(0.981)PIY(0.043)S(0.066)PDPY(0.779)Y(0.512)AS(0.353)ES(0.33)EY(0.518)WT(0.251)Y(0.162)HGS(0.027)PK 59.661 0.01567 0.0 25470.4 14209.4 19500.4 26573.6 31391.1 32342.2 29902.0 32332.9 30813.5 23642.7 True False 29782.035656669126 15620.0153253469 19965.363491678825 25084.767344773605 25240.239297896835 30646.118096810857 27069.46608826736 31484.195634539345 31264.089144085217 27928.93435448978 1.0663505910629723 0.55927716851237 0.7148630605903962 0.898164141402017 0.9037308397640057 1.0972892022242255 0.9692266000802765 1.1272967036595163 1.1194157552616857 1.0 14.769472907308995 -6.381487211620743 1.5375060897967379 1.068256649149424 0.7661953316515786 0.45791857611489184 0.1298039229353529 0.32524405966388864 1.5433126536663868 0.04884836652251874 0.060389970807155774 4.154442843718426e-07 6.381487211620743 -0.3020613174978455 Y(ph)S(ph)PIYSPDPY(ph)Y(ph)ASESEYWT(ph)YHGSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSPIYSPDPYYASESEYWTYHGSPK 25 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 5 Y(0.973)S(0.984)PIY(0.097)S(0.131)PDPY(0.834)Y(0.879)AS(0.112)ES(0.209)EY(0.081)WT(0.489)Y(0.132)HGS(0.078)PK 58.086999999999996 0.018557 0.0 4616.9 3714.4 3639.9 6235.2 6723.1 7476.4 6857.6 8503.9 7546.2 5150.4 True False 5398.449982068428 4083.141084385587 3726.6890203976195 5885.861958791145 5405.756817177167 7084.324422550001 6207.99848327544 8280.68163562684 7656.548898992184 6084.126749456035 0.8873007095966711 0.671113744425303 0.6125265258043502 0.9674127777363257 0.8885016765405949 1.164394614754433 1.0203598213713216 1.3610304282972394 1.2584466455562806 1.0 12.570834493429114 -6.522835880367701 1.104990685575715 1.202664962248819 0.7276784293109838 0.6505576435267371 0.13300195233191933 0.2834335783197816 0.7346438435981215 0.06302918381725732 0.07229011607917192 3.0002961149395953e-07 6.522835880367701 -0.4749865329378352 Y(ph)S(ph)PIYSPDPY(ph)Y(ph)ASESEYWTY(ph)HGSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSPIYSPDPYYASESEYWTYHGSPK 25 0 O94929;A0A0C4DGA7;O94929-2;O94929-3 O94929 ABLIM3 Actin-binding LIM protein 3 5 Y(0.857)S(0.875)PIY(0.144)S(0.192)PDPY(0.474)Y(0.409)AS(0.359)ES(0.313)EY(0.366)WT(0.33)Y(0.431)HGS(0.25)PK 50.857 0.020444 0.0 12913.0 12611.0 10819.0 19563.0 20633.0 22896.0 20130.0 23456.0 18683.0 16378.0 True False 15098.915856624497 13862.93673680451 11076.965991285988 18466.94853410175 16590.111765229813 21695.293453895567 18223.14067142072 22840.304853686306 18956.20353023655 19347.201751823344 0.7804185871582967 0.7165344588138189 0.5725358185321068 0.9545022981094082 0.8574941212708606 1.1213659593874308 0.9419005862025143 1.180548233624212 0.9797904510118656 1.0 14.239837299371482 -6.166213666266354 1.541048266370889 1.04425038321893 0.6979380814441629 0.6549578995746347 0.10253458319294154 0.22195949558774158 1.0522296491022172 0.035153996689354525 0.052053264025578375 6.820030764693016e-07 6.166213666266354 -0.34631230177476713 Y(ph)S(ph)S(ph)QRMK ddPTM_PC-9_AZD4547_30min_R2 2 YSSQRMK 7 1 J3QQS7;J3KTA5;J3QL95;J3KRI2;J3KRK4;J3KS63;J3QS62;J3QQY1;Q96JB5;Q96JB5-4 J3QQS7 CDK5RAP3 CDK5 regulatory subunit-associated protein 3 3 Y(1)S(1)S(1)QRMK;Y(1)S(1)S(1)QRMK 40.882 0.044892 0.0 6158.200000000001 5062.55 5661.23 10449.3 7615.5 10054.5 4988.36 5263.139999999999 4610.49 6301.18 True False 8116.379501482711 6698.92028393895 5586.1583912180295 8040.37532507568 6558.219278098641 9425.790525554707 5432.314376266205 4449.842647925406 4854.1910888981165 6080.577606129921 1.3348040313309162 1.1016914375347613 0.9186887748273355 1.3223045318869144 1.078552022999789 1.550147228785046 0.8933878865043688 0.7318124915368982 0.798310851917182 1.0 12.569992659304486 -7.497009225262664 24.325510372898993 0.8215569805341651 1.1993057157687346 0.5104011944438164 0.17316769494213718 414.8503755414837 390091.6551402748 0.07188419643949216 0.04824087186135403 3.1841298838726727e-08 7.497009225262664 0.3777487352345694 Y(ph)S(ph)S(ph)QRMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSSQRMK 7 1 J3QQS7;J3KTA5;J3QL95;J3KRI2;J3KRK4;J3KS63;J3QS62;J3QQY1;Q96JB5;Q96JB5-4 J3QQS7 CDK5RAP3 CDK5 regulatory subunit-associated protein 3 3 Y(1)S(1)S(1)QRMK 60.43600000000001 0.023005 0.0 1305.0 2220.5 1138.6 2014.1 3006.5 2733.0 3468.3 3337.6 3544.0 3185.6 True False 1525.9107250751154 2440.9365652267384 1165.7485421645454 1901.2565068003018 2417.397907340835 2589.6766688284692 3139.757515682488 3249.9915364795147 3595.824295410711 3763.124062804275 0.40549041158584836 0.6486463173918735 0.3097821179182254 0.5052335440101031 0.6423912331870858 0.6881720149557454 0.8343486590614142 0.8636418789917931 0.9555423194661053 1.0 11.877715137671938 -7.075290340479492 0.8099878543906468 0.9764795624047974 0.45561732473722705 0.8523310303905719 0.0842796427974615 0.23418089072650156 0.3144984322275874 0.063836073395766 0.04492374740615814 8.408328286551939e-08 7.075290340479492 -0.5208622376675703 down Y(ph)S(ph)S(ph)QRMK ddPTM_PC-9_Lapatinib_30min_R1 1 YSSQRMK 7 1 J3QQS7;J3KTA5;J3QL95;J3KRI2;J3KRK4;J3KS63;J3QS62;J3QQY1;Q96JB5;Q96JB5-4 J3QQS7 CDK5RAP3 CDK5 regulatory subunit-associated protein 3 3 Y(1)S(1)S(1)QRMK 47.574 0.038778 0.0 926.13 2145.4 2626.5 988.48 3856.2 2118.4 1132.8 1721.5 2178.0 2346.7 True False 912.9232163685583 2140.432458112984 2410.5593085831947 1061.1761166726158 3629.3858975808994 2027.8009702315926 1191.4508411670308 1801.4871746447284 1932.6907046432302 2752.323968218802 0.33169177281094825 0.7776818727841074 0.8758268780921222 0.38555639849307716 1.3186623157337465 0.7367595507093982 0.4328890257559658 0.6545331129062476 0.7022032024427681 1.0 11.426434580223237 -4.759276551177111 24.804673529572884 0.7517676576421044 0.33169117524322295 0.205506913039752 0.25435837170149955 88.9887190906317 1020307.8918258508 0.06286881615516511 0.40378607807855493 1.7406980741204783e-05 4.759276551177111 -0.42007648239888146 Y(ph)S(ph)SRNFPAER ddPTM_PC-9_AZD4547_30min_R2 1 YSSRNFPAER 10 1 Q71RC2-5;Q71RC2-3;Q71RC2;Q71RC2-4;X6RLN4;Q71RC2-2;Q96J85;Q71RC2-7 Q71RC2-5 LARP4 La-related protein 4 2 Y(0.999)S(0.904)S(0.097)RNFPAER 78.113 0.030831 0.0 969.63 928.07 1177.6 4892.5 2608.9 553.66 882.37 4463.6 2464.9 469.06 True False 1277.9521704430958 1228.0504781019886 1161.9842545698286 3764.609713371493 2246.6992678920033 519.0395526757784 960.8992206228123 3773.853183323996 2595.1895818069165 452.63835217075217 2.8233404533980018 2.7130941781944315 2.567136101033446 8.317036537706688 4.96356364218219 1.1466981314919094 2.122885115710047 8.337457851782645 5.733472582164035 1.0 8.822215019501938 Y(ph)SIS(ph)LS(ph)PPEQQKK ddPTM_PC-9_Lapatinib_30min_R1 1 YSISLSPPEQQKK 13 1 A0A0U1RQT1;A0A087X1H5;Q15057;H7C3K3 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 3 Y(0.946)S(0.267)IS(0.973)LS(0.815)PPEQQKK 57.106 0.045447 0.0 7880.3 8475.4 8668.3 9148.5 8947.9 7164.0 7537.2 8523.4 8304.4 7028.5 True False 7767.925476929969 8455.775732027021 7955.625834605639 9821.311208501362 8421.602114248253 6857.6124200996655 7927.439336197164 8919.42828020149 7369.0710227912 8243.366860112437 0.942324369247351 1.0257672472327268 0.9650942351117352 1.1914198864573402 1.021621657407758 0.8318946052591586 0.9616749406794005 1.0820127784631717 0.8939394725289089 1.0 13.009017986184885 -6.5491555856230645 24.998650848127763 0.9558760677742068 1.0361075936934794 0.15838621553343268 0.086698087820599 424.0513329091535 403421.077631396 0.029274665607713024 0.029275490499442714 2.8238681453587477e-07 6.5491555856230645 0.08023152591927263 Y(ph)SLVSEQLEPAATSTYR ddPTM_PC-9_AZD4547_30min_R2 2 YSLVSEQLEPAATSTYR 17 0 Q9Y446;Q9Y446-2;E9PKC4;E9PK71;E9PQ15;E9PJR7;E9PRW6 Q9Y446 PKP3 Plakophilin-3 1 Y(0.972)S(0.028)LVSEQLEPAATSTYR;Y(0.856)S(0.144)LVSEQLEPAATSTYR 214.47 4.235199999999999e-22 7897700.0 10546.3 12859.6 16751.5 15324.400000000001 18783.6 27030.0 17818.6 23258.8 20037.3 17000.7 True False 13899.804023332637 17016.21421681591 16529.364164764334 11791.596339619853 16175.821368537016 25339.809827017125 19404.420880797905 19664.686894053266 21096.430771041298 16405.510667610342 0.8472643311722834 1.0372255129132488 1.0075495057522663 0.7187582623014709 0.9859992594118508 1.5445913474090087 1.1827989554210194 1.1986635035310158 1.2859356345848052 1.0 14.001892882041098 -6.5450476932316715 24.94762955292141 1.2526679937088376 0.9113703133031098 0.5421982487260557 0.14975453594016963 171.29490679854848 192763.84340034114 0.048159153942255443 0.04816238407781732 2.8507051923567964e-07 6.5450476932316715 -0.34129768040572783 Y(ph)SLVSEQLEPAATSTYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSLVSEQLEPAATSTYR 17 0 Q9Y446;Q9Y446-2;E9PKC4;E9PK71;E9PQ15;E9PJR7;E9PRW6 Q9Y446 PKP3 Plakophilin-3 1 Y(0.638)S(0.362)LVSEQLEPAATSTYR 233.52 4.834e-37 2495100.0 4682.1 6317.8 7192.3 3181.5 9174.0 5340.6 9297.4 3926.8 5677.9 4953.0 True False 5474.6870543097275 6944.989431114384 7363.791708949648 3003.250869562168 7376.4205561100325 5060.529534411019 8416.682964653104 3823.7256607885165 5760.928545968532 5850.9396920735735 0.9356936393869235 1.1869870134745961 1.2585656486812837 0.5132937660647492 1.2607240792625276 0.864908852379158 1.4385181539395138 0.6535233418947424 0.9846159504554487 1.0 12.514452632473212 Y(ph)SLVSEQLEPAATSTYR ddPTM_PC-9_Lapatinib_30min_R1 2 YSLVSEQLEPAATSTYR 17 0 Q9Y446;Q9Y446-2;E9PKC4;E9PK71;E9PQ15;E9PJR7;E9PRW6 Q9Y446 PKP3 Plakophilin-3 1 Y(0.959)S(0.041)LVSEQLEPAATSTYR;Y(0.958)S(0.042)LVSEQLEPAATSTYR 255.39 1.7970999999999997e-57 7498800.0 12941.0 12476.2 14027.5 12085.599999999999 18639.300000000003 17015.2 18641.2 15142.800000000001 18281.800000000003 9877.599999999999 True False 12756.458966911256 12447.312125435448 12874.21309771588 12974.41534037974 17542.97302027376 16287.499560368484 19606.350123907887 15846.389769509247 16222.711168111391 11584.929998925314 1.1011252522108135 1.0744399945955767 1.1112896753722437 1.1199390364536794 1.5142925353801144 1.4059212754742072 1.6924012597164322 1.367845103162406 1.4003288038526176 1.0 13.499961706401436 -6.247721123630771 20.522551989705523 1.4304266853932393 1.1004360723842408 0.4304728577895176 0.16356301474635465 61.63351658638417 92202.00253911449 0.04609218695149169 0.05895667177770891 5.652998580017139e-07 6.247721123630771 -0.32999061300899846 Y(ph)SPPAISPLVSEK ddPTM_PC-9_Lapatinib_30min_R1 1 YSPPAISPLVSEK 13 0 Q14694;Q14694-3;Q14694-2 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 Y(0.564)S(0.436)PPAISPLVSEK 81.625 0.016565 13856000.0 23705.0 40763.0 35642.0 25568.0 38545.0 37275.0 35140.0 38125.0 30635.0 26620.0 True False 23366.962353035393 40668.61577797127 32711.65234209869 27448.35601234767 36277.8588823857 35680.83514226896 36959.3772586595 39896.42668215522 27184.563699148468 31221.231531079626 0.7484317948756894 1.3025948620087937 1.0477374125852597 0.8791567361788343 1.1619611752429555 1.1428388116833237 1.1837898585732518 1.2778620421311615 0.8707076039613364 1.0 14.930239825537248 Y(ph)SPPRDDDKVDNQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSPPRDDDKVDNQAK 15 2 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 Y(0.879)S(0.121)PPRDDDKVDNQAK 76.58800000000001 0.019795 30251000.0 15281.0 13797.0 12243.0 13683.0 16306.0 15069.0 12210.0 12649.0 12514.0 11047.0 True False 17867.771486492602 15166.674978803556 12534.91955183606 12916.38587088454 13110.956353600408 14278.755112541592 11053.380407255183 12316.977152723317 12696.99357583793 13049.733651996117 1.3692058369144957 1.1622210370924795 0.9605498384956455 0.9897815706689783 1.0046914905113735 1.0941798118889179 0.8470196175662507 0.9438489306514914 0.9729695574204895 1.0 13.671732740914285 -4.916952479312656 2.0821238818984753 0.9743377505786347 1.4224630422287237 0.8160135367589132 0.05890688503506595 0.21342346974908463 1.3073219800645526 0.016666049498541974 0.16486944985712523 1.2107306049617237e-05 4.916952479312656 0.44812529165008896 Y(ph)SPPRDDDKVDNQAK ddPTM_PC-9_Lapatinib_30min_R1 1 YSPPRDDDKVDNQAK 15 2 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 Y(0.565)S(0.435)PPRDDDKVDNQAK 79.639 0.015307 114450000.0 26015.0 20890.0 19333.0 18483.0 20087.0 18706.0 19017.0 12570.0 16894.0 11443.0 True False 25644.02132943328 20841.630488477786 17743.515367538144 19842.301477480516 18905.522152561465 17905.987985815776 20001.607209104364 13154.048089041078 14991.21981829327 13420.907303160942 1.9107516913847922 1.5529226167569972 1.3220801669168167 1.4784620018057335 1.4086620021664829 1.3341861009351053 1.4903319691652672 0.9801161569712197 1.1170049445734926 1.0 13.71219458592544 -1.5228787452805659 0.16572701335891227 0.9261492288493379 4.290520338151357 0.7296674466927614 0.1384428072170784 35.02175761189425 0.37218011189550293 0.402873046044274 29.011452580870078 0.029999999999984227 1.5228787452805659 3.3643711093020188 Y(ph)SYLTEPGMIERS(ph)T(ph)GATR ddPTM_PC-9_AZD4547_30min_R2 1 YSYLTEPGMIERSTGATR 18 1 Q12955 Q12955 ANK3 Ankyrin-3 3 Y(0.445)S(0.078)Y(0.445)LT(0.033)EPGMIERS(0.942)T(0.964)GAT(0.095)R 66.44800000000001 0.008884999999999999 22690000.0 0.0 0.0 3667.5 6033.5 0.0 0.0 2974.6 4607.4 3788.4 0.0 True False 0.0 0.0 3618.866553698071 4642.569791645766 0.0 0.0 3239.333637436241 3895.4321975192634 3988.6470898281123 0.0 0.0 Y(ph)SYLTEPGMIERS(ph)T(ph)GATR ddPTM_PC-9_Lapatinib_30min_R1 1 YSYLTEPGMIERSTGATR 18 1 Q12955 Q12955 ANK3 Ankyrin-3 3 Y(0.494)S(0.269)Y(0.206)LT(0.031)EPGMIERS(0.919)T(0.926)GAT(0.155)R 50.924 0.041755 11816000.0 2851.4 1156.5 1588.5 2009.1 2013.5 0.0 1158.7 1618.5 2177.4 1841.0 True False 2810.73851311728 1153.8221953051486 1457.899661787324 2156.855916161128 1895.0698886933087 0.0 1218.6918164373583 1693.70141862474 1932.1582829615095 2159.214397021696 1.3017412800666117 0.5343712958271623 0.67519912047561 0.9989077134425273 0.8776663824154127 0.0 0.5644144546823864 0.7844063197063433 0.894843182606889 1.0 11.076290786087899 -4.7528253620585525 24.93262327136865 0.6840631046960972 1.3017424863613956 0.2861655426145945 0.2820756895430264 436.7571350789956 1264061.945753219 0.07354642970249571 0.8420584518055629 1.7667481203580613e-05 4.7528253620585525 0.6176793816652983 Y(ph)T(ph)LWEVS(ph)CSGT(ph)VSEQLR ddPTM_PC-9_AZD4547_30min_R2 1 YTLWEVSCSGTVSEQLR 17 0 P46091 P46091 GPR1 G-protein coupled receptor 1 4 Y(0.992)T(0.992)LWEVS(0.526)CS(0.479)GT(0.506)VS(0.506)EQLR 43.798 0.041879 23777000.0 47592.0 39815.0 42571.0 60283.0 55046.0 53997.0 39773.0 37228.0 27761.0 26386.0 True False 62725.26602490421 52684.42012523915 42006.48072460273 46385.6857130657 47403.813063123634 50620.559053993464 43312.71994948959 31475.268014334986 29228.389784795236 25462.234171273354 2.4634627740432626 2.0691200847048226 1.6497562799102166 1.821744525678674 1.8617303078849579 1.988064311776061 1.7010573250620427 1.236154997342911 1.1479114357439568 1.0 14.636071392912921 -7.72840156868001 1.7657472424373746 1.05781294773713 1.9594904057788822 0.7827523733878253 0.20075757759302568 0.1858882847041135 1.119298355269774 0.1586249057090497 0.06520538742886398 1.8689532209443706e-08 7.72840156868001 0.9016774580417521 Y(ph)T(ph)LWEVS(ph)CSGT(ph)VSEQLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YTLWEVSCSGTVSEQLR 17 0 P46091 P46091 GPR1 G-protein coupled receptor 1 4 Y(0.998)T(0.998)LWEVS(0.5)CS(0.5)GT(0.502)VS(0.502)EQLR 43.913999999999994 0.041599000000000004 14956000.0 37419.0 53902.0 39828.0 46865.0 28428.0 41872.0 43508.0 27345.0 41830.0 43217.0 True False 43753.2976410619 59253.03433409218 40777.65056853114 44239.305988379994 22857.737472105506 39676.158608556776 39386.60726935781 26627.22272442244 42441.684615414815 51051.89999441624 0.8570356371819144 1.160643077741924 0.7987489314401847 0.8665555247349978 0.44773529436917237 0.7771730065462074 0.771501301100756 0.5215716305825008 0.8313438798567113 1.0 15.639677034315866 -5.620988580717813 2.2386728100451054 0.7094326388514087 1.0034690494458434 0.25061242469986156 0.16909912801770285 0.3432610149097517 3.4581636115020253 0.0467782138321926 0.10172079328818644 2.3933786867635475e-06 5.620988580717813 0.29403641059443464 Y(ph)T(ph)S(ph)SKKRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YTSSKKRK 8 3 U3KQK0 U3KQK0 HIST1H2BN Histone H2B 3 Y(1)T(1)S(0.5)S(0.5)KKRK 63.48 0.024406 0.0 4800.3 3618.3 4534.1 5385.9 5651.8 5062.6 6107.4 7087.0 4484.8 5134.9 True False 5612.895979753314 3977.5009114883615 4642.210139670007 5084.145484323395 4544.370361785773 4797.108343802053 5528.8628582530955 6900.973759297197 4550.381715591974 6065.816722153964 0.9253322737651364 0.655723885781362 0.7653066936090288 0.8381633862682916 0.7491769979116798 0.7908429422672378 0.9114787194377681 1.1376825373066448 0.7501680192500342 1.0 12.566486192443795 -7.3385865362998315 3.9511674892125983 0.9678686489523525 0.7804406286315496 0.34967131645396254 0.1091949596547649 0.23852062122036252 7.116178607237771 0.04542198617536238 0.029962254656887812 4.5857826167638326e-08 7.3385865362998315 -0.18742802032080286 Y(ph)T(ph)SS(ph)KKRK ddPTM_PC-9_Lapatinib_30min_R1 1 YTSSKKRK 8 3 U3KQK0 U3KQK0 HIST1H2BN Histone H2B 3 Y(0.98)T(0.858)S(0.32)S(0.842)KKRK 50.108000000000004 0.046033 0.0 3531.1 4295.0 6979.0 4674.4 4438.3 3110.3 2606.3 3037.7 4953.4 3588.2 True False 3480.7458664755686 4285.0551913840145 6405.213559719062 5018.170969341286 4177.247920033531 2977.279719463425 2741.241461276157 3178.842631669062 4395.495930385575 4208.41558902404 0.8270917624090394 1.0182110347086106 1.5220011959903594 1.1924133591818182 0.992593965987628 0.7074585806659547 0.6513713779659935 0.7553537820646314 1.0444538656898474 1.0 12.039061465199813 -6.526086948937857 4.157618132271638 0.8063093110519745 1.154645858594486 0.34389459909904796 0.19847348947369226 0.23153198532334052 9.476212047100915 0.0702348184030191 0.07413058166630618 2.977920168302888e-07 6.526086948937857 0.34833654754251164 Y(ph)TPSQQGVAFNSGAK ddPTM_PC-9_AZD4547_30min_R2 1 YTPSQQGVAFNSGAK 15 0 G3V3A4;Q13573;G3V4X8 G3V3A4 SNW1 SNW domain-containing protein 1 1 Y(0.742)T(0.045)PS(0.213)QQGVAFNSGAK 78.705 0.016853 4843600.0 11369.0 10974.0 13409.0 15086.0 14864.0 17429.0 15233.0 21199.0 17482.0 13269.0 True False 14984.105510109584 14521.130891733636 13231.187898715041 11608.155776376565 12800.390171316165 16339.16187477178 16588.707489768793 17923.18165455807 18406.06282978964 12804.456348769276 1.1702258262257117 1.1340685224116807 1.033326799539348 0.9065715451083798 0.9996824404455483 1.2760527608298067 1.2955417268741165 1.3997612367416747 1.4374731990522014 1.0 13.644358379881576 -6.820964110570936 5.708682749303586 1.3109834551523338 1.0448762189080358 0.44221080023468773 0.1290110593598341 0.17442019689436522 11.330253374107592 0.04636165408484545 0.041275058107409064 1.510204950025544e-07 6.820964110570936 -0.266107236244298 Y(ph)TPSQQGVAFNSGAK ddPTM_PC-9_Lapatinib_30min_R1 2 YTPSQQGVAFNSGAK 15 0 G3V3A4;Q13573;G3V4X8 G3V3A4 SNW1 SNW domain-containing protein 1 1 Y(0.738)T(0.152)PS(0.111)QQGVAFNSGAK;Y(0.996)T(0.004)PSQQGVAFNSGAK 126.83 3.2607e-05 9784800.0 21966.5 28199.0 37475.0 27220.0 25275.0 26897.0 22356.6 18040.4 22927.0 17738.8 True False 21653.253681837257 28133.706948041407 34393.950157683335 29221.849603258135 23788.374192561914 25746.67800996937 23514.115356316062 18878.622843718127 20344.71982798684 20804.92794453474 1.0407752307320712 1.352261686416072 1.6531636278374282 1.4045638456986074 1.1434009411607167 1.2375278625626187 1.1302185433664529 0.9074111140422078 0.9778798504962478 1.0 14.34463767133311 -7.148520999040092 1.1064674377682908 0.9537782314165475 1.3638541298222997 0.5105317951738855 0.15293251673705377 0.4266873602770235 1.0409744168254915 0.10751379214079507 0.06738624756047525 7.103608217516319e-08 7.148520999040092 0.4100758984057522 Y(ph)TRGT(ph)PS(ph)T(ph)RVR ddPTM_PC-9_Lapatinib_30min_R1 1 YTRGTPSTRVR 11 2 Q8NCL9 Q8NCL9 APCDD1L Protein APCDD1-like 4 Y(0.935)T(0.167)RGT(0.994)PS(0.95)T(0.954)RVR 41.54 0.045528 0.0 24983.0 25209.0 27426.0 28614.0 29412.0 26146.0 21106.0 22849.0 26609.0 20383.0 True False 24626.737838678913 25150.630109336358 25171.14014742156 30718.36901350579 27682.04398621683 25027.796529302872 22198.765407548857 23910.647954375476 23612.014214807958 23906.174391359713 1.030141311425371 1.0520558286576551 1.0529137676047005 1.2849554475185363 1.157945371477831 1.0469176757260057 0.9285787447268035 1.000187130025178 0.9876952216721856 1.0 14.545095659402556 -6.994294384977974 5.281038843843195 0.9796144635878259 1.1173224455180486 0.45618233940595865 0.0702342772623621 0.17688657538742122 15.500062811253592 0.028753617183345348 0.02409462328753691 1.0132243423724571e-07 6.994294384977974 0.1377079819302227 Y(ph)VELY(ph)LVADY(ph)LEFQK ddPTM_PC-9_AZD4547_30min_R2 1 YVELYLVADYLEFQK 15 0 E5RIS2;Q9H013-2;Q9H013 E5RIS2 ADAM19 Disintegrin and metalloproteinase domain-containing protein 19 3 Y(1)VELY(1)LVADY(1)LEFQK 55.31399999999999 0.040752 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 487.28 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 470.22047551648876 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 8.877193551570716 Y(ph)VLARP ddPTM_PC-9_AZD4547_30min_R2 1 YVLARP 6 1 Q13470-2;Q13470 Q13470-2 TNK1 Non-receptor tyrosine-protein kinase TNK1 1 Y(1)VLARP 87.758 0.036349 7040000.0 29971.0 27110.0 40901.0 56730.0 45233.0 43518.0 32955.0 56319.0 36765.0 39446.0 True False 39501.15456447308 35872.77733505545 40358.62601576133 43651.77496976287 38953.1787284139 40796.812580544974 35887.931157705716 47616.19263187207 38708.32284276493 38065.00754642795 1.0377287989840396 0.9424082549123723 1.0602553005285984 1.1467691137725569 1.023333009481284 1.0717668328525887 0.9428063586729399 1.250917724731685 1.0169004379035609 1.0 15.216177743767437 -5.393356696563332 7.16913652058774 1.071138352107679 0.9907198538523098 0.10882752500293713 0.08328254357525698 0.47804412795691487 25.47781308654225 0.02101654561550484 0.04405265835292786 4.042437401518441e-06 5.393356696563332 -0.08041849825536918 Y(ph)VLARP ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YVLARP 6 1 Q13470-2;Q13470 Q13470-2 TNK1 Non-receptor tyrosine-protein kinase TNK1 1 Y(1)VLARP 89.775 0.034762 5479900.0 21679.0 20625.0 21791.0 22029.0 29111.0 27811.0 22775.0 23541.0 20515.0 16623.0 True False 25348.826520232524 22672.513694123612 22310.58008282771 20794.78654898161 23406.908525062034 26352.542201532593 20617.58712327901 22923.07369375127 20814.993064433052 19636.61831240441 1.2908957192603638 1.1546037781770924 1.1361722129484058 1.0589800248775822 1.1920030298840172 1.3420102067618103 1.049956097086988 1.167363612668013 1.060009047040664 1.0 14.261258879263549 -8.350947204045374 1.179874835159091 1.000301857317168 1.1782403924569775 0.33458161625214733 0.08463940045115408 0.5779035877946513 1.6863258292647814 0.08204636701575828 0.026349244874047863 4.457104288632365e-09 8.350947204045374 0.1779385351398095 Y(ph)VLARP ddPTM_PC-9_Lapatinib_30min_R1 1 YVLARP 6 1 Q13470-2;Q13470 Q13470-2 TNK1 Non-receptor tyrosine-protein kinase TNK1 1 Y(1)VLARP 87.758 0.036349 7310100.0 44958.0 47840.0 59631.0 42878.0 41328.0 47054.0 36469.0 40464.0 48533.0 30795.0 True False 44316.89067571256 47729.22941928081 54728.36936231661 46031.39115681491 38897.1682939742 45041.61010823137 38357.18637581253 42344.10516109455 43066.702464853035 36117.874718241794 1.227007154253452 1.321484993001943 1.5152710337819337 1.274476738066932 1.0769506400200421 1.2470725495230353 1.062000094829493 1.1723864012327425 1.1923930408646566 1.0 15.140425382455113 -6.052532084276699 5.666460727176321 1.1386338733790264 1.3582933488215925 0.5522193815743222 0.09388805659059787 0.15798142514027264 11.519740941751447 0.027398001492004286 0.03638625827549541 8.860697612630769e-07 6.052532084276699 0.21965947544256603 Y(ph)VLCPSTTPSPAQPADR ddPTM_PC-9_AZD4547_30min_R2 1 YVLCPSTTPSPAQPADR 17 0 M0R0W6;P30530-2;P30530 M0R0W6 AXL Receptor protein-tyrosine kinase;Tyrosine-protein kinase receptor UFO 1 Y(1)VLCPSTTPSPAQPADR 126.95 5.1256000000000005e-05 9660300.0 11519.0 18849.0 13429.0 15187.0 16469.0 9647.9 17273.0 14306.0 11910.0 12938.0 True False 15181.802389915767 24941.570637715256 13250.922685647281 11685.871786811016 14182.563625632794 9044.615287831239 18810.263537765146 12095.336419175796 12539.538285253102 12485.044558020707 1.2159990554589246 1.9977157888228891 1.0613436439147153 0.9359895939901727 1.1359641977826629 0.7244359638284791 1.5066236608407584 0.9687860033631556 1.004364720284269 1.0 13.60791334967587 -5.33803438495713 10.589486941563539 1.0454128769607924 1.6063900314437953 0.43922611944961454 0.25520311831295606 0.47831051435919536 64.47964140489812 0.06258213604118208 0.1304047702531825 4.591616575995851e-06 5.33803438495713 0.5609771544830029 Y(ph)VLGQLVGLNSPNSILK ddPTM_PC-9_Lapatinib_30min_R1 1 YVLGQLVGLNSPNSILK 17 0 P33981-2;P33981 P33981-2 TTK Dual specificity protein kinase TTK 1 Y(0.498)VLGQLVGLNS(0.416)PNS(0.086)ILK 97.911 0.0020408 6155000.0 33024.0 28043.0 30494.0 26884.0 28534.0 26623.0 24136.0 18198.0 25036.0 21454.0 True False 32553.071704140104 27978.0681564568 27986.901030244044 28861.139042394978 26855.68622000241 25484.396351244173 25385.643981645007 19043.545515065205 22216.182039232295 25162.29531434193 1.2937242527944421 1.1119044509627842 1.1122554870537646 1.1469994562040131 1.0672987453849367 1.012800940171728 1.0088763232651425 0.7568286309798941 0.8829155592403203 1.0 14.618975910970882 -6.892439336718229 0.9620908239928481 0.8729975087236935 1.1716771169622215 0.6804502263622426 0.0789638090427251 0.3111737854074288 0.6091582942280842 0.04948350733647525 0.03967382176805291 1.2810340199053993e-07 6.892439336718229 0.298679608238528 Y(ph)VNILPY(ph)DHSR ddPTM_PC-9_AZD4547_30min_R2 1 YVNILPYDHSR 11 0 P18433-6;P18433 P18433-6 PTPRA Receptor-type tyrosine-protein phosphatase alpha 2 Y(1)VNILPY(0.986)DHS(0.014)R 57.148999999999994 0.031083999999999997 0.0 586.12 882.55 2225.6 4232.6 2513.4 3065.0 765.8 3454.0 0.0 964.33 True False 772.4939679466471 1167.817028294106 2196.087089818794 3256.8394630181297 2164.457794442009 2873.345065475673 833.9547164488245 2920.26366502399 0.0 930.5691002192083 0.830130688591181 1.2549492864302185 2.359939836065345 3.4998362424143856 2.3259506402395496 3.087728858393017 0.8961770987800638 3.1381481120919252 0.0 1.0 9.861969472613886 -8.270990373204418 24.942791719189742 0.4999998587345286 2.186772149802872 0.34892955882302545 0.9145895883073235 832.0990418584346 2173032.7823073803 0.8561574926123796 0.23272189700925439 5.358085343901575e-09 8.270990373204418 1.6867722910683431 Y(ph)Y(ph)AFPQMIT(ph)PLVT(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 YYAFPQMITPLVTK 14 0 A0A1W2PR36;Q14353 A0A1W2PR36 GAMT Guanidinoacetate N-methyltransferase 4 Y(1)Y(1)AFPQMIT(1)PLVT(1)K 51.073 0.039971 0.0 10465.0 6521.9 9932.7 16372.0 14403.0 12774.0 10296.0 11556.0 10960.0 11903.0 True False 13792.652314477697 8629.976632294285 9800.985908089107 12597.68834487852 12403.392063876929 11975.239760648052 11212.32405400509 9770.285730462423 11539.323224716536 11486.279592991235 1.2007937124300698 0.7513291455625174 0.8532776717423394 1.0967596812257165 1.079844170905025 1.0425690636988476 0.9761493234803975 0.8506049022543481 1.0046179993526945 1.0 13.487623964139173 -4.707866557315041 24.06842958853265 0.9645206742475565 1.20080202114431 0.3170544716482594 0.10520573390166568 20721.545293271294 9307965.459195988 0.028264526751659167 42.631106179838135 1.959446646742927e-05 4.707866557315041 0.2362813468967535 Y(ph)Y(ph)CQY(ph)EK ddPTM_PC-9_AZD4547_30min_R2 1 YYCQYEK 7 0 O60890 O60890 OPHN1 Oligophrenin-1 3 Y(1)Y(1)CQY(1)EK 44.135 0.042792000000000004 0.0 6161.1 6542.6 7730.5 11709.0 10362.0 10102.0 8470.9 8586.6 9019.0 8051.3 True False 8120.2016411589575 8657.367502483732 7627.988518981034 9009.670952246674 8923.415161139535 9470.320343045758 9224.793689692284 7259.738270438621 9495.725927346572 7769.42643762499 1.0451481465652688 1.114286565679895 0.9817955778615761 1.1596314122514313 1.1485294613159764 1.218921424776461 1.1873197801345268 0.9343982247237579 1.2221913681248893 1.0 12.923592383148781 -3.5062165140540835 14.074730889183586 1.1050430092361554 0.7538491662353987 0.0 0.09866554987694537 0.0 0.0 0.022119851636501823 0.0 0.0003117335074065361 3.5062165140540835 -0.35119384300075673 Y(ph)Y(ph)HVFREGELCS(ph)LLK ddPTM_PC-9_AZD4547_30min_R2 1 YYHVFREGELCSLLK 15 1 Q9P272 Q9P272 KIAA1456 Probable tRNA methyltransferase 9-like protein 3 Y(1)Y(1)HVFREGELCS(1)LLK 54.004 0.043541 0.0 1917.2 781.83 851.6 839.48 2519.6 2672.3 2186.9 1181.8 603.21 2321.7 True False 2526.829719762697 1034.5412579810559 840.3072275744446 645.9508558367102 2169.797031461799 2505.200658554859 2381.529863413339 999.1799650623478 635.0944491223777 2240.4179896704813 1.1278385245131606 0.4617626098124731 0.3750671666843901 0.28831711708033375 0.968478668474239 1.1181844950831348 1.0629846191172623 0.44597926354327583 0.28347141116099805 1.0 11.129552202377168 -6.274946308257799 24.657959757020954 0.8132221790206019 0.5425561262554139 0.12149870284253939 0.3273606953491182 1487.2470603873453 2715080.572288013 0.10994357321757064 0.12538211081604986 5.309500814286907e-07 6.274946308257799 -0.27066605276518796 Y(ph)Y(ph)IAAS(ph)Y(ph)VK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YYIAASYVK 9 0 Q92820 Q92820 GGH Gamma-glutamyl hydrolase 4 Y(1)Y(1)IAAS(1)Y(1)VK 44.203 0.031833 3265000.0 45653.0 47100.0 44069.0 57156.0 61750.0 56948.0 64098.0 65918.0 56463.0 47217.0 True False 53381.15121214882 51775.77672694408 45119.772092613166 53953.73462225218 49650.53077608399 53961.54662877558 58026.173410666925 64187.722345894144 57288.66455749856 55777.068330433685 0.9570447642731775 0.9282627839135393 0.8089305057289006 0.9673103344661333 0.8901602802417842 0.9674503921413973 1.0403231139168003 1.1507905357383466 1.0271006754623584 1.0 15.767384487162442 -7.151402450785382 2.520150006255635 1.0702604553565755 0.9092292953590845 0.599957137786447 0.055100211053454126 0.1859120915309506 2.3027545413588024 0.023926442123311888 0.0172616608093724 7.056633290788301e-08 7.151402450785382 -0.16103115999749107 Y(ph)Y(ph)MS(ph)LK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YYMSLK 6 0 P29374;P29374-3;P29374-2 P29374 ARID4A AT-rich interactive domain-containing protein 4A 3 Y(1)Y(1)MS(1)LK 44.611000000000004 0.037268 0.0 888.61 2639.8 4621.4 3271.1 5366.8 6329.3 3867.2 2799.9 4202.2 2711.8 True False 1039.0341221524886 2901.861898169575 4731.5917027570995 3087.830872049287 4315.214065896152 5997.3803659041405 3500.8708198965805 2726.405591739271 4263.649225218649 3203.4278734030104 0.32435071530070686 0.9058614749102869 1.4770401862460902 0.9639145921425337 1.3470614093496314 1.8721758700104918 1.0928514573289254 0.8510900508719751 1.3309646396656225 1.0 11.645400792612293 -4.870464514033198 2.950554833088591 1.247300631562589 0.25542760678837073 0.49960933817683517 0.28117153438954856 0.27850601051393437 3.9309078124632224 0.0753916757349839 0.598201366903992 1.3475208260427755e-05 4.870464514033198 -0.9918730247742182 Y(ph)YKINGT(ph)T(ph)T(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 YYKINGTTTR 10 1 Q32MC3;Q9UBL9-7;Q9UBL9-5;Q9UBL9-6;Q9UBL9-2;Q9UBL9-3;Q9UBL9;Q9UBL9-4 Q32MC3 P2RX2 P2X purinoceptor;P2X purinoceptor 2 4 Y(0.5)Y(0.5)KINGT(1)T(1)T(1)R 60.828 0.030652999999999996 98212000.0 450880.0 517300.0 421940.0 312520.0 343380.0 455970.0 335150.0 320020.0 196940.0 223950.0 True False 594250.4611133974 684507.1086471474 416344.79990930186 240473.3423858682 295707.6141702464 427458.1238189056 364977.7007284198 270568.26232801896 207349.8463390213 216109.57866507466 2.749764562885772 3.167407538691251 1.9265448689553486 1.1127380094454413 1.368322570414763 1.9779693545253618 1.6888548068202942 1.2519956958841887 0.9594662467986708 1.0 17.721403492892186 -5.429952921703269 3.664001533237623 1.393630996259296 2.9495813149858714 0.8054368012155297 0.31419539976499167 0.1028552670408066 2.5282569286004115 0.09040710042816633 0.20185772690043935 3.715755063619447e-06 5.429952921703269 1.5559503187265753 up Y(ph)YKINGT(ph)T(ph)T(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YYKINGTTTR 10 1 Q32MC3;Q9UBL9-7;Q9UBL9-5;Q9UBL9-6;Q9UBL9-2;Q9UBL9-3;Q9UBL9;Q9UBL9-4 Q32MC3 P2RX2 P2X purinoceptor;P2X purinoceptor 2 4 Y(0.5)Y(0.5)KINGT(1)T(1)T(1)R 56.632 0.039067000000000005 16049000.0 58891.0 171600.0 103540.0 87077.0 54609.0 73519.0 90192.0 38531.0 65334.0 64070.0 True False 68860.08314973074 188635.31393510842 106008.78627763643 82198.35799744315 43908.75846398657 69663.53421719733 81648.36082646674 37519.6020769691 66289.38615021537 75685.38382215906 0.9098200956677976 2.49236119854201 1.4006507059107935 1.0860532621541286 0.5801484546495889 0.9204357657865421 1.0787863746363384 0.49573114625580017 0.8758545283456337 1.0 16.20772709689042 -5.744048540996705 2.871773817757036 0.8229967604261752 1.7389878984507963 0.43233086749063177 0.39805356206326337 0.2063953599064193 3.47692057621556 0.10858857196008703 0.19464039412126813 1.8028162292332752e-06 5.744048540996705 0.9159911380246211 YAALSVDGEDENEGEDYAE ddPTM_PC-9_AZD4547_30min_R2 2 YAALSVDGEDENEGEDYAE 19 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 ; 218.54 2.0088999999999998e-86 1905400.0 45910.0 38427.0 59248.0 77115.0 70341.0 57186.0 51048.0 67181.0 50115.0 54716.0 False True 60508.425012677566 50847.77626905849 58462.332808044506 59337.32816487341 60575.366324041366 53610.15037986685 55591.17310692036 56799.72011580106 52763.97658819977 52800.4094942542 1.1459840102047345 0.9630185969408401 1.1072325644445322 1.1238043176792136 1.1472518282388178 1.015335882682894 1.0528549615314982 1.0757439319098854 0.9993099881913151 1.0 15.688261498016491 -8.259733497454135 7.677938604340307 0.999301609722137 1.0768266092064547 0.24912821610803648 0.05493905252749494 0.16752271776699537 97.34934712539544 0.043688513927274505 0.014046883495247875 5.498782002401068e-09 8.259733497454135 0.07752499948431768 YAALSVDGEDENEGEDYAE ddPTM_PC-9_Lapatinib_30min_R1 1 YAALSVDGEDENEGEDYAE 19 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 173.72 7.0077e-08 2106500.0 52536.0 51482.0 66131.0 49557.0 51915.0 50949.0 43341.0 47141.0 59135.0 42381.0 False True 51786.82700607753 51362.79659204464 60693.96445304213 53201.58709730578 48861.46176881703 48770.03003791985 45584.984910858315 49331.342956681416 52474.59358084361 49706.499380867215 1.0418522255866416 1.0333215420882154 1.2210468491853634 1.070314501322213 0.9829994543454925 0.9811600222383027 0.9170829867050478 0.992452567996969 1.0556887778148762 1.0 15.601146883479833 -6.192382774228551 4.4545651445715215 0.983752119218057 1.0993048022052943 0.44164222351310445 0.057195517047180275 0.20981939343160644 8.13835245909132 0.018069154354546278 0.023411272413955492 6.421215210450132e-07 6.192382774228551 0.1155526829872372 YACGLWGLS(ph)PASR ddPTM_PC-9_AZD4547_30min_R2 2 YACGLWGLSPASR 13 0 Q15637-6;H7C0N4;H7C561 Q15637-6 SF1 Splicing factor 1 1 YACGLWGLS(0.998)PAS(0.002)R;YACGLWGLS(1)PASR 214.61 2.3128e-14 24232000.0 42624.0 42731.0 61941.0 80122.0 72167.0 59847.0 51329.0 73879.0 51933.0 56771.0 True False 56177.545365723534 56542.960099751166 61119.62186846959 61651.11077256016 62147.857743095665 56104.757629208034 55897.1815625512 62462.69812052913 54678.072356679215 54783.46456974758 1.0254471090305193 1.0321172737763507 1.115658207243449 1.1253598372565328 1.1344272990250936 1.0241184647564276 1.020329437021744 1.1401742954939393 0.99807620394409 1.0 15.741452886183113 -6.786970384976942 24.94977303760467 1.0442874352089766 1.087342512943281 0.18881475650328128 0.05061310889991271 474.3679480865726 463565.4753473234 0.018769076454493064 0.016558387120280873 1.633163311317319e-07 6.786970384976942 0.04305507773430439 YACGLWGLS(ph)PASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YACGLWGLSPASR 13 0 Q15637-6;H7C0N4;H7C561 Q15637-6 SF1 Splicing factor 1 1 YACGLWGLS(1)PASR;YACGLWGLS(0.98)PAS(0.02)R;YACGLWGLS(1)PASR;YACGLWGLS(0.973)PAS(0.027)R 196.84 9.280500000000001e-07 12480000.0 59561.9 54354.3 65131.8 71796.6 73936.5 63900.0 64248.1 60887.0 51534.7 45898.7 True False 69644.55326885181 59750.23568894559 66684.78912572705 67774.06926971771 59449.17358260614 60548.971510478994 58162.05485203697 59288.780765109084 52288.29749342621 54219.77097609072 1.2844863048123711 1.102000886637711 1.2298980229026242 1.2499881141070115 1.0964482607058859 1.116732336202218 1.072709342090078 1.0934900627163042 0.9643769523940589 1.0 15.726531398804823 -7.172282788272241 0.6160405603679089 0.9899589472443077 1.2178655632276438 0.6866408170587661 0.05554776581501176 0.4817804510587986 0.37649248287391884 0.04861482339992909 0.037734716695941854 6.72538594168218e-08 7.172282788272241 0.22790661598333617 YACGLWGLS(ph)PASR ddPTM_PC-9_Lapatinib_30min_R1 2 YACGLWGLSPASR 13 0 Q15637-6;H7C0N4;H7C561 Q15637-6 SF1 Splicing factor 1 1 YACGLWGLS(1)PASR;YACGLWGLS(1)PASR 188.96 2.5410999999999998e-05 14542000.0 42910.0 42259.0 48766.0 42044.0 38356.0 36645.0 36021.0 26887.0 37768.0 33053.0 True False 42298.09553126976 42161.1518818852 44756.64772220376 45136.05601467246 36099.9754907974 35077.77877366723 37885.9911278934 28136.268175819227 33514.17012532853 38766.16700964595 1.0911085308161879 1.0875759749834049 1.1545285792909894 1.1643156777259287 0.931223751933351 0.9048554830024604 0.9772952564143487 0.7257944322640474 0.8645211201042755 1.0 15.242510475754179 -6.366669284417093 4.1541424069367645 0.8857191172539755 1.1236627941688144 0.6925836543917966 0.07307716539962016 0.13453884967002103 4.012512098798164 0.02414669603535528 0.027643129369718526 4.298636436572822e-07 6.366669284417093 0.23794367691483898 YADEEIPRS(ph)PFK ddPTM_PC-9_AZD4547_30min_R2 2 YADEEIPRSPFK 12 1 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 1 YADEEIPRS(1)PFK;YADEEIPRS(1)PFK 54.598 0.039725 32404000.0 93863.0 85817.0 101348.0 124949.0 110080.0 99050.0 91841.0 97541.0 87508.0 94775.0 True False 123709.48152831524 113555.66700709915 100004.05930039316 96143.93849280641 94797.29211911211 92856.3878418811 100014.67108040795 82468.27971919648 92133.49422887735 91456.95609726477 1.3526525133501033 1.2416296348889233 1.0934549275184549 1.0512479596473452 1.0365235862244844 1.0153015342335252 1.0935709578399047 0.901716864833017 1.0073973392564375 1.0 16.480805283207133 -3.8887014956692894 0.5759032675831308 0.9931492328927427 2.220978724610536 0.8736197445553435 0.043711078566140496 3.119404659437865 0.36349753839169596 0.021695079381176357 3.2095194461197454 0.0001292107074523207 3.8887014956692894 1.2278294917177934 YADEEIPRS(ph)PFK ddPTM_PC-9_Lapatinib_30min_R1 2 YADEEIPRSPFK 12 1 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 1 YADEEIPRS(1)PFK;YADEEIPRS(1)PFK 87.863 0.0039386 28077000.0 99631.0 78840.0 78030.0 71676.0 85115.0 77744.0 75474.0 74588.0 80261.0 73604.0 True False 98210.24366991235 78657.45082391523 71614.67460451057 76947.29214412687 80108.70304252853 74419.07035011552 79381.67442288184 78053.63077688101 71221.1609942012 86326.35332883468 1.1376623694019543 0.9111638310990964 0.8295806766181315 0.8913534416427733 0.9279750615362861 0.8620666514967696 0.9195531997106475 0.9041692109888948 0.8250222353642725 1.0 16.39751342577835 -4.7652825683019495 4.951180309978669 0.8909670855667748 1.1530855614994935 0.692616615926251 0.048185406520202576 0.08860257723180867 5.624227176514111 0.01124268108080313 0.08081573728670237 1.716791014978143e-05 4.7652825683019495 0.26211847593271864 YADLTEDQLPSCESLK ddPTM_PC-9_Lapatinib_30min_R1 2 YADLTEDQLPSCESLK 16 0 P18669 P18669 PGAM1 Phosphoglycerate mutase 1 0 ; 247.32 2.9974999999999992e-127 0.0 17769.7 16855.1 16184.1 15164.9 17256.5 17744.7 17816.4 16798.1 16235.7 20656.6 False True 17516.30081943611 16816.073051524254 14853.505770432634 16280.177334623399 16241.506597584344 16985.800545916045 18738.84601568529 17578.60105047899 14407.06449649959 24227.06578681064 0.7230054590008209 0.694102752660994 0.6130955313011521 0.6719830406984912 0.670386861558213 0.7011084501682914 0.7734674178284863 0.7255769726785851 0.5946681543393044 1.0 14.56433206576037 -11.617827122392834 2.49919768029044 1.5408696933071035 0.68682073313584 0.7809929762733916 0.04999393000622686 13452331.948687268 3729847.708692705 41432809.98866692 0.012989326638910184 2.410864919615256e-12 11.617827122392834 -0.8540489601712635 YADSPGAS(ph)SPEQPK ddPTM_PC-9_AZD4547_30min_R2 4 YADSPGASSPEQPK 14 0 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 YADSPGAS(0.5)S(0.5)PEQPK;YADSPGAS(0.605)S(0.395)PEQPK;YADSPGAS(0.5)S(0.5)PEQPK;YADS(0.002)PGAS(0.499)S(0.499)PEQPK 250.05 1.9138999999999998e-35 67747200.0 424783.0 401111.0 463579.0 611727.0 555166.0 509833.0 462326.0 516920.0 481903.0 508084.0 True False 559855.1579647172 530762.2865968801 457431.63956286194 470702.7912379362 478090.7837627092 477953.061914082 503472.11835586355 437041.8916398958 507375.40875552705 490296.1338087331 1.141871451474915 1.0825341054064543 0.9329701134076416 0.9600377379715574 0.9751061670602826 0.9748252718234441 1.0268735232415078 0.8913835160086904 1.0348346106956183 1.0 18.90329385984797 -5.086314537074854 3.997961696015316 0.9723377099593762 1.1319783418726572 0.6610521989219746 0.04032464370817282 0.11633106617571745 3.3236202246068163 0.009825426170638122 0.03199558581944333 8.197576211529206e-06 5.086314537074854 0.15964063191328104 YADSPGAS(ph)SPEQPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YADSPGASSPEQPK 14 0 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 YADSPGAS(0.5)S(0.5)PEQPK;YADSPGAS(0.5)S(0.5)PEQPK;YADSPGAS(0.874)S(0.126)PEQPK;YADSPGAS(0.5)S(0.5)PEQPK 232.78 2.8220000000000003e-48 56489300.0 201788.0 195730.0 173338.0 230234.0 243287.0 213936.0 229485.0 210069.0 197220.0 181329.0 True False 235946.72290533097 215160.7808654939 177471.03530802604 217334.73540869897 195616.6588003426 202716.81954719615 207746.51947247842 204554.91133650384 200103.96939641712 214202.5123004258 1.1015123976436292 1.0044736569836497 0.8285198590907156 1.0146227188217107 0.9132323272006447 0.946379280850261 0.9698603309615126 0.9549603743657736 0.9341812439424846 1.0 17.708615875449865 -4.90408021302992 4.144747200511309 0.9442497349111559 1.0978159039325097 0.49088614745567616 0.048696202989747105 0.16972526001860674 5.012179730624595 0.011487951011902304 0.058603612455366605 1.2471531471169213e-05 4.90408021302992 0.15356616902135378 YADSPGAS(ph)SPEQPK ddPTM_PC-9_Lapatinib_30min_R1 3 YADSPGASSPEQPK 14 0 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 YADSPGAS(0.639)S(0.361)PEQPK;YADSPGAS(0.5)S(0.5)PEQPK;YADSPGAS(0.5)S(0.5)PEQPK 217.19 1.1965999999999998e-74 36828800.0 108930.0 92385.0 98632.0 101316.0 105042.0 92005.0 84364.0 84826.0 91401.0 79519.0 True False 107376.6382246846 92171.08820861734 90522.8576905303 108767.11662026822 98863.6360805178 88070.16062413041 88731.95512377775 88767.32563253774 81106.45688480073 93263.75319759273 1.1513222934229517 0.9882841409281437 0.9706113531453593 1.1662313909866933 1.06004350769651 0.944312850433341 0.9514087958243144 0.9517880482942966 0.8696460747506589 1.0 16.509028868530294 -6.762175555370544 6.874263718149551 0.9405529569501717 1.0633359146835568 0.4805002140084188 0.06431712337911907 0.1296005632807419 31.03918214252857 0.0225005049259361 0.02108651854133621 1.7291172548178158e-07 6.762175555370544 0.1227829577333851 YADSPGAS(ph)SPEQPKR ddPTM_PC-9_AZD4547_30min_R2 1 YADSPGASSPEQPKR 15 1 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 YADSPGAS(0.829)S(0.171)PEQPKR 73.593 0.0079238 17958000.0 36835.0 31689.0 48866.0 65012.0 57741.0 47162.0 40156.0 55059.0 47678.0 48027.0 True False 48547.763784403796 41931.849537830065 48218.00491152281 50024.48782538737 49724.65883220982 44212.95268449059 43729.80620752028 46550.89667995249 50198.161743433855 46345.5893482811 1.047516375713202 0.9047646200530033 1.0404011598422183 1.0793796891751624 1.0729102711055296 0.9539840426288676 0.9435591783912047 1.0044299216939185 1.083127055871513 1.0 15.500144425452199 YADSPGASS(ph)PEQPK ddPTM_PC-9_Lapatinib_30min_R1 1 YADSPGASSPEQPK 14 0 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 YADSPGAS(0.362)S(0.638)PEQPK 244.23 6.2836e-35 35799000.0 180560.0 163290.0 169980.0 159410.0 168560.0 166560.0 155860.0 151930.0 159970.0 119750.0 True False 177985.18128935166 162911.91203750743 156004.9005417745 171133.54317617085 158645.6322017106 159436.6170703237 163929.66817116286 158989.22244773354 141952.49404122005 140448.62794315524 1.2672618016702082 1.1599395054499493 1.110761299889063 1.218477856867601 1.1295634177780673 1.1351952625329569 1.1671859709267596 1.132009794443007 1.010707588390778 1.0 17.099683005136264 YADSPGASS(ph)PEQPKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YADSPGASSPEQPKR 15 1 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 YADSPGAS(0.199)S(0.801)PEQPKR 87.38799999999999 0.002374 12727000.0 28139.0 27183.0 40733.0 38857.0 48994.0 45101.0 38212.0 48411.0 34167.0 27246.0 True False 32902.37692941659 29881.548593811494 41704.22920076271 36679.96826609372 39393.977406371814 42735.82416422713 34592.2827290774 47140.26254569444 34666.627737386494 32185.484120782687 1.0222737929292478 0.9284169373272374 1.2957465248699993 1.139643204633634 1.223967216355602 1.3277980844983444 1.0747790090483866 1.464643575619085 1.0770889015462002 1.0 14.974122548984289 -5.256632676780181 24.98887115295289 1.2157796669420446 0.9753453465108576 0.3093579855937463 0.13297428949772408 403.63997212966774 2098406.943495937 0.03132387860617125 0.07744898405059043 5.538183268278774e-06 5.256632676780181 -0.24043432043118707 YADSPGASS(ph)PEQPKR ddPTM_PC-9_Lapatinib_30min_R1 1 YADSPGASSPEQPKR 15 1 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 YADSPGAS(0.311)S(0.689)PEQPKR 88.637 0.002194 14090000.0 33697.0 33965.0 37522.0 29434.0 32269.0 27135.0 30745.0 31256.0 36527.0 24258.0 True False 33216.474600727044 33886.356129303356 34437.08599910855 31598.674548945615 30371.000863294972 25974.499304774483 32336.82566355966 32708.26786563787 32412.944613637854 28450.962978246767 1.1674991326699178 1.1910442593880712 1.2104014203469562 1.1106363806773623 1.0674858663489262 0.9129567714328068 1.1365810601308635 1.1496365831499686 1.1392565038455944 1.0 14.796189863730843 -5.9230125994658716 3.906531432297222 1.0718439889964886 1.1893487500450184 0.3893876655913501 0.06803318041575397 0.2610978850170741 7.814643047474429 0.02139579977973453 0.03260999190248384 1.1939534657691377e-06 5.9230125994658716 0.1175047610485298 YAEEDRR ddPTM_PC-9_AZD4547_30min_R2 1 YAEEDRR 7 1 P38646;H0Y8S0 P38646 HSPA9 Stress-70 protein, mitochondrial 0 76.847 0.0194 3953200.0 4580.3 2184.2 5797.6 15016.0 8377.5 4712.1 2346.0 3202.4 5066.4 7623.3 False True 6036.740123841586 2890.199935641023 5720.720035915456 11554.29319488735 7214.428731176076 4417.451642097201 2554.7894551958007 2707.5426638311587 5334.1995607394 7356.410587351934 0.8206094605731644 0.3928818139392896 0.7776509981309685 1.5706427826028286 0.9806995742706408 0.6004900881541658 0.34728750181349527 0.36805214060323205 0.7251090049147918 1.0 12.844786288583435 -6.824791575935208 6.11187071900239 0.5482050488997209 0.9089420993966416 0.16671650642049773 0.323100083653513 0.35093585366367963 24.827325165665407 0.12401758059437971 0.11010384107293632 1.4969538930817234e-07 6.824791575935208 0.36073705049692073 YAEEDRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 YAEEDRR 7 1 P38646;H0Y8S0 P38646 HSPA9 Stress-70 protein, mitochondrial 0 ;; 101.69 0.0070348 9762400.0 12267.400000000001 4385.6900000000005 8531.699999999999 19598.9 26095.800000000003 38217.2 15306.599999999999 42919.5 36008.1 21815.6 False True 14344.02852780572 4821.072319184534 8735.128084652433 18500.837173491116 20982.515320267732 36213.02275446443 13856.648037812625 41792.908601969204 36534.65034186752 25770.59558780541 0.5566044633672838 0.1870764803536731 0.33895716747756804 0.7179049126146574 0.8142037404132256 1.4052070558897116 0.5376921922739559 1.6217284718768983 1.4176874654443625 1.0 14.653438259457268 -6.270601712185975 1.1499407114187394 1.2251523270033269 0.3176840557786552 0.5916729943663321 0.29633746485695917 0.33207127570300893 0.9085043085627977 0.1252042572349976 0.18372051736002967 5.362882575049566e-07 6.270601712185975 -0.9074682712246717 YAEERDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YAEERDR 7 1 P35579;P35579-2;P35580-4;P35580-3;P35580-2;P35580-5;P35580 P35579 MYH9;MYH10 Myosin-9;Myosin-10 0 76.035 0.041281 2302300.0 6017.7 921.27 3614.8 6637.0 11990.0 16931.0 7100.9 17685.0 16830.0 8245.9 False True 7036.377755007298 1012.7275971386794 3700.9905412053417 6265.150407444319 9640.64557093518 16043.108554677943 6428.251345935986 17220.787488806393 17076.106910768136 9740.81639549152 0.7223601666759724 0.1039674249077741 0.379946648303352 0.6431853504952735 0.989716383053611 1.6469983524279754 0.6599294232577122 1.7678998134875978 1.7530467896583815 1.0 13.249826976925398 -6.305165966780036 1.8639328373691542 1.3761743351200628 0.37607202386715444 0.5913833270112285 0.35428444902606926 0.2380801857261798 1.6293283068404574 0.12539414623354617 0.1596624137932379 4.952608893828572e-07 6.305165966780036 -1.0001023112529084 YAELLEEHR ddPTM_PC-9_Lapatinib_30min_R1 1 YAELLEEHR 9 0 P40222 P40222 TXLNA Alpha-taxilin 0 157.99 9.199100000000001e-05 1805400.0 19161.0 18409.0 22610.0 17875.0 15413.0 18213.0 17177.0 14917.0 15961.0 16105.0 False True 18887.760626302956 18366.375091545582 20751.09307712395 19189.587129251977 14506.437643123898 17434.07244657665 18066.341012293513 15610.09827718582 14163.304103218832 18888.727791436417 0.9999487967032963 0.9723457976811094 1.0985966501424131 1.0159279831409271 0.7679944252095519 0.9229881778740406 0.9564615050720489 0.8264240159288531 0.7498283769878906 1.0 14.205237915008171 -6.16934200969839 8.645570133430533 0.8689678810931907 1.0244483258697028 0.4658908346076168 0.07924288322698449 0.3187874907116701 27.530417531398363 0.023644935843110493 0.030571779482512215 6.771080706341408e-07 6.16934200969839 0.15548044477651213 YAEYS(ph)FTSLPVPESNLR ddPTM_PC-9_Lapatinib_30min_R1 1 YAEYSFTSLPVPESNLR 17 0 Q5UIP0;Q5UIP0-2 Q5UIP0 RIF1 Telomere-associated protein RIF1 1 YAEYS(0.968)FT(0.008)S(0.024)LPVPESNLR 80.488 0.041027999999999995 0.0 10150.0 9154.0 14395.0 7854.3 10361.0 11238.0 11075.0 12294.0 11633.0 8684.3 True False 10005.259138717971 9132.804475420084 13211.498666306912 8431.931423176713 9751.586350509753 10757.376937057517 11648.409309608818 12865.224121453539 10322.769039079294 10185.36968389762 0.9823167395225338 0.8966591060370082 1.2971054636527724 0.827847361937881 0.9574111351035547 1.056159694828181 1.1436412885458802 1.263108215089393 1.0134898741475131 1.0 13.314210724256462 -7.027328944110587 4.201464272691604 1.1254324706618268 0.9950982265249266 0.12992289438610338 0.13347127149991128 0.398033908237431 16.046723635315306 0.051095229614679896 0.041067205672534454 9.390118131239648e-08 7.027328944110587 -0.1303342441369002 YALPLVGHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YALPLVGHR 9 0 A0A499FI48;P13667 A0A499FI48 PDIA4 Protein disulfide-isomerase A4 0 ; 173.68 0.0010827999999999999 4917100.0 56553.0 55585.0 60822.0 68318.0 69070.0 60213.0 65459.0 56868.0 56491.0 45613.0 False True 66126.30592733574 61103.11145153265 62272.227148719496 64490.36394994435 55536.22932314372 57055.32428107156 59258.249637880224 55375.27525662658 57317.07400452781 53882.27582769069 1.2272366916868924 1.1340113332802304 1.1557089263983373 1.1968752796592539 1.0306956874045592 1.058888538107186 1.0997725824978382 1.0277085443404492 1.063746345603909 1.0 15.71752316680073 -3.1105210031697483 0.20409192306053842 0.9936761835987912 1.6190066572382225 0.7071403618876624 0.03934722486588141 16.02899899264084 0.34273435524843776 0.07648549287073642 2.8301279526820333 0.0007753164469202212 3.1105210031697483 0.6253304736394313 YALPLVGHR ddPTM_PC-9_Lapatinib_30min_R1 2 YALPLVGHR 9 0 A0A499FI48;P13667 A0A499FI48 PDIA4 Protein disulfide-isomerase A4 0 ; 143.11 0.00052306 4925700.0 74705.0 72366.0 75641.0 71956.0 70256.0 79566.0 70374.0 67507.0 75184.0 58446.0 False True 73639.69300078071 72198.44097315367 69422.08896270377 77247.88427817951 66123.68020861037 76163.1476574051 74017.6213773735 70643.62166641958 66715.98619738141 68548.3132256002 1.0742743261737777 1.0532489798186644 1.0127468597838123 1.1269115262391365 0.9646288449285384 1.111087116129957 1.0797876401972606 1.0305668854888301 0.9732695533705054 1.0 16.064833545466392 -8.053205231387453 4.283613374559656 0.9884361426208267 1.0590448355639324 0.3053889843112936 0.04412905465825485 0.27017821065474 10.126954222273344 0.029861468985667407 0.010982262841528595 8.84697435993378e-09 8.053205231387453 0.07060869294310568 YALYDASFETK ddPTM_PC-9_AZD4547_30min_R2 1 YALYDASFETK 11 0 P60981;F6RFD5;P60981-2 P60981 DSTN Destrin 0 137.98 0.0004457 5263300.0 27126.0 25324.0 27160.0 33868.0 32978.0 26550.0 25743.0 23158.0 18542.0 16986.0 False True 35751.50374414923 33509.48776218903 26799.840653971256 26060.255855383908 28399.573941715866 24889.824302896945 28034.077129200974 19579.46321789971 19522.092265756753 16391.325310136017 2.1811234337495167 2.044342792798306 1.6350014502731425 1.589880949972291 1.732597785985873 1.5184754028099028 1.710299600476195 1.1945015334295281 1.1910014532921718 1.0 14.000644886888669 -1.5228787452809018 0.132479011996677 0.7885982844605581 5.384632567874817 0.8433298551667171 0.14052653287465897 32.69176295807442 0.2930559083736453 0.7694401111166288 28.14456436051594 0.029999999999961023 1.5228787452809018 4.596034283414259 up YALYDASFETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YALYDASFETK 11 0 P60981;F6RFD5;P60981-2 P60981 DSTN Destrin 0 ; 158.79 4.5652999999999997e-07 3394400.0 42224.0 37060.0 39498.0 49433.0 45876.0 45786.0 47197.0 41917.0 44433.0 38822.0 False True 49371.689237985986 40739.071878992516 40439.782116999144 46663.42927394835 36886.92712362153 43384.90155835356 42726.158483310646 40816.72316473266 45082.7485660226 45860.12128521707 1.0765712748758225 0.8883332781791984 0.8818071340346594 1.0175164819939153 0.8043355771828707 0.946026751401955 0.9316625705715992 0.8900264984229307 0.9830490479002493 1.0 15.48495254993588 -10.609672052138906 8.203510962431842 1.0000000027277332 0.9299321804553761 0.06071613771735063 0.07326044221484895 2.8192337050411016e-09 3.646139423657343e-10 0.06691009695458125 0.016228081702486494 2.456563234802105e-11 10.609672052138906 -0.07006782227235708 YALYDASFETK ddPTM_PC-9_Lapatinib_30min_R1 2 YALYDASFETK 11 0 P60981;F6RFD5;P60981-2 P60981 DSTN Destrin 0 ; 197.06 0.00047726 46893000.0 106250.0 79258.0 106375.0 90116.0 97254.0 84621.0 98545.0 82168.0 90213.0 93055.0 False True 104734.85551613622 79074.48297059706 97629.25811937451 96743.4312581635 91533.7109287206 81001.95709118561 103647.17791561193 85985.82524903164 80052.26195499535 109139.43276200653 0.9596426595374093 0.7245271573202126 0.8945369757626327 0.8864205064096842 0.8386859690605354 0.7421878146262815 0.9496767143881789 0.7878529608682822 0.7334861463826761 1.0 16.735812925059832 -4.291689221971985 7.638112176196035 0.8368170788752662 8.124959674380897 0.1388167825224409 0.08933442760645052 10637.421742629665 5562.776789335774 0.021030899587958878 1319300.710878122 5.1087044444472564e-05 4.291689221971985 7.28814259550563 YALYDATYETK ddPTM_PC-9_AZD4547_30min_R2 2 YALYDATYETK 11 0 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;Q9Y281-3;Q9Y281 P23528;Q9Y281 CFL1;CFL2 Cofilin-1;Cofilin-2 0 ; 185.29 0.00067454 34135000.0 111765.0 89758.0 126489.0 155446.0 137998.0 114780.0 112527.0 128091.0 106923.0 113897.0 False True 147303.9451435834 118770.51818664353 124811.67321355549 119610.3263167594 118839.35971887005 107602.78845523561 122541.68500631642 108297.47918835757 112574.7314923691 109909.50069754843 1.340229408820061 1.080621033057725 1.1355858449126723 1.0882619387554668 1.0812473804780083 0.9790126219510314 1.114932596623558 0.985333192317679 1.0242493212862 1.0 16.745956574252745 -1.5228787452803376 0.6799444109411131 1.0344144848002934 31.24706082509541 0.7460842060412375 0.0505613811445991 128.5753689766262 0.7393413102894172 0.019745999973795263 5884.039357750866 0.029999999999999995 1.5228787452803376 30.212646340295116 YALYDATYETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YALYDATYETK 11 0 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;Q9Y281-3;Q9Y281 P23528;Q9Y281 CFL1;CFL2 Cofilin-1;Cofilin-2 0 ;;; 177.78 0.009986100000000001 38292600.0 161396.0 158451.0 159753.0 182813.0 206191.0 176312.0 183832.0 165847.0 163813.0 138264.0 False True 188717.1550836965 174180.96811382173 163562.11738662666 172570.58029774256 165789.35370447856 167065.88834046287 166418.10213157543 161493.69197942203 166208.45522125167 163330.1687027784 1.1554335404325473 1.0664347529744438 1.001420121498009 1.0565750446984443 1.0150565264288391 1.0228721960391933 1.0189060811809747 0.9887560471042045 1.0176225037991056 1.0 17.317431770039185 -4.806748107521636 2.1607398259959107 1.0163393317932308 1.1888586479144887 0.8581939644873565 0.017481189687354924 0.21630830252036382 1.2197742227840442 0.004689242512655609 0.07200078009720602 1.5604573116783352e-05 4.806748107521636 0.17251931612125793 YALYDATYETK ddPTM_PC-9_Lapatinib_30min_R1 4 YALYDATYETK 11 0 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;Q9Y281-3;Q9Y281 P23528;Q9Y281 CFL1;CFL2 Cofilin-1;Cofilin-2 0 ;;; 185.29 0.0033284 158989000.0 547885.0 463314.0 540612.0 450686.0 447483.0 428453.0 495738.0 467202.0 435365.0 445504.0 False True 540072.0594301976 462241.2248989274 496164.9681826689 483830.95188442327 421162.92972542695 410129.06396272476 521404.88797533687 488909.91052475525 386329.60910330585 522508.7728032343 1.0336133813270485 0.8846573473188317 0.9495820816955242 0.925976705211462 0.8060399205661337 0.7849228286874538 0.9978873372365116 0.9356970370119859 0.7393743975448799 1.0 18.995095734354678 -1.5228843982538476 1.02306648531619 0.8836833045744455 166.42011357132492 0.1917888205642485 0.08510485028959773 2887.891825696357 3.5679204890907963 0.02613030503340768 1121372.2113395627 0.029999609508965353 1.5228843982538476 165.53643026675047 YAPSEAGLHEMDIR ddPTM_PC-9_AZD4547_30min_R2 4 YAPSEAGLHEMDIR 14 0 Q60FE5;P21333-2;P21333;A0A087WWY3;H0Y5F3 Q60FE5 FLNA Filamin-A 0 ;;; 104.81 0.0006998999999999999 32747100.0 82447.0 72058.0 137467.0 211036.0 167620.0 149341.0 126805.0 192038.0 124176.0 162451.0 False True 108663.43099586658 95349.33932900876 135644.09776065795 162384.91067369792 144348.85633180916 140002.68366172977 138090.39934616507 162362.93969423164 130739.6898496717 156763.6399362362 0.6931673125226332 0.6082363191349233 0.8652778017646908 1.035858256032765 0.9208057199394147 0.8930813530400036 0.880882833559705 1.035718102490303 0.833992435381382 1.0 17.25823145119454 -5.382397759844544 4.248271360725992 0.9394793074066585 0.652158981320416 0.7502051515338366 0.06626072021772846 0.09943262012595813 2.935516094850833 0.016958916228007673 0.037585180221711305 4.145741702163693e-06 5.382397759844544 -0.2873203260862425 YAPSEAGLHEMDIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 YAPSEAGLHEMDIR 14 0 Q60FE5;P21333-2;P21333;A0A087WWY3;H0Y5F3 Q60FE5 FLNA Filamin-A 0 ;; 111.72 0.00025302 17135800.0 62810.0 64104.0 78432.0 80358.0 97266.0 80110.0 82298.0 77161.0 78728.0 61755.0 False True 73442.49244595246 70467.82147142297 80302.11633501647 75855.8017841511 78207.4255298231 75908.89057440491 74502.1376540776 75135.60550883738 79879.24806125689 72950.692647689 1.0067415370631034 0.9659650774221309 1.1007725001711874 1.0398229136835226 1.0720587110463937 1.04055064892944 1.0212670359948632 1.0299505430565312 1.094975868797147 1.0 16.154634055768586 -5.243441153391355 24.980081374511055 1.0500658777445817 0.9863533025269812 0.3965602734957887 0.03136744524916537 787.0834641865455 1092404.767283609 0.007646164316940231 0.020144250578312366 5.708984272821145e-06 5.243441153391355 -0.06371257521760054 YAPSEAGLHEMDIR ddPTM_PC-9_Lapatinib_30min_R1 4 YAPSEAGLHEMDIR 14 0 Q60FE5;P21333-2;P21333;A0A087WWY3;H0Y5F3 Q60FE5 FLNA Filamin-A 0 ;;; 140.33 2.6074e-05 26585400.0 93823.0 87327.0 132381.0 98911.0 110675.0 124047.0 107245.0 103589.0 125512.0 85814.0 False True 92485.06681496925 87124.79969685506 121497.14518543756 106185.24489742356 104165.31409542201 118741.79897768034 112797.62134618484 108402.1231102369 111375.51686004638 100646.83556003246 0.918906851868234 0.8656486735232529 1.2071630917096106 1.0550281517205538 1.0349586603077143 1.1797867098052461 1.1207269529989827 1.0770544598551106 1.1065973037335548 1.0 16.61894228759406 -5.247336994172972 24.998312422704664 1.1004107479237275 0.8922777295374358 0.6485815727776807 0.060446048667942516 456.5538360211219 809297.6339148174 0.01486724208897189 0.03893633598622405 5.658000816936213e-06 5.247336994172972 -0.20813301838629172 YAPSGFYIASGDVSGK ddPTM_PC-9_Lapatinib_30min_R1 1 YAPSGFYIASGDVSGK 16 0 O75083;D6RD66 O75083 WDR1 WD repeat-containing protein 1 0 166.62 0.00022317 4320000.0 14974.0 14564.0 18975.0 13728.0 13698.0 15752.0 14522.0 14133.0 14549.0 14048.0 False True 14760.468014104717 14530.2779528095 17414.94874561818 14737.602915265517 12892.310571304171 15078.323679705447 15273.878103308283 14789.670775053102 12910.338412237996 16476.17808221662 0.8958672296724121 0.8818961460784766 1.056977453066911 0.8944794625139666 0.7824818660596625 0.915159062038791 0.9270279810700744 0.8976396529129635 0.7835760421995334 1.0 14.008094004273351 -5.979700854817877 24.997798882994253 0.8788382342091627 0.9447979583475856 0.11475335412030518 0.07481286601405844 487.43197618225076 600253.8882203455 0.02094579934167035 0.031064582050136774 1.0478500662378103e-06 5.979700854817877 0.06595972413842288 YARS(ph)EIVGVSR ddPTM_PC-9_AZD4547_30min_R2 1 YARSEIVGVSR 11 1 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 YARS(1)EIVGVSR 144.51 0.00086321 39522000.0 30377.0 29521.0 42433.0 73875.0 54381.0 50216.0 38705.0 42078.0 37690.0 52459.0 True False 40036.25411914847 39063.08593538074 41870.31069477033 56844.26010737238 46831.13683438805 47075.9855817052 42149.6700184797 35575.81195624767 39682.21645433997 50622.42637727692 0.7908797934885179 0.771655740960594 0.8271099133558089 1.1229066675651935 0.9251065226578971 0.9299432870099719 0.8326284027626061 0.7027678146264581 0.7838861013614369 1.0 15.62748903829342 -10.029335199638897 10.678774829376605 1.0000002572079716 0.8580226788324701 0.13392039445174952 0.11090740813173329 0.0 0.0 0.11959937437124618 0.02900710901708458 9.346839825619621e-11 10.029335199638897 -0.1419775783755015 YARS(ph)EIVGVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YARSEIVGVSR 11 1 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 YARS(0.961)EIVGVS(0.039)R 101.72 0.01745 28617000.0 34903.0 26499.0 29915.0 43649.0 47494.0 38464.0 33146.0 47631.0 41726.0 24869.0 True False 40811.38853432702 29129.64559421002 30628.287053269276 41203.48804196734 38187.891638531706 36446.8801279979 30006.17092374123 46380.73671921608 42336.16381216345 29377.55283710432 1.3892031361707429 0.9915613378599326 1.0425744861425374 1.402550044601628 1.2999003644136005 1.2406370377441687 1.0213979050645414 1.5787814926720674 1.4411058690597334 1.0 14.842426603326002 -5.7566116592831325 24.998983644779297 1.2955764559633522 1.1261578273989346 0.09882195383133163 0.19305411194709302 250.8994828427154 1299191.188235848 0.05328774180996887 0.08865445395085071 1.7514120795126573e-06 5.7566116592831325 -0.1694186285644177 YARS(ph)EIVGVSR ddPTM_PC-9_Lapatinib_30min_R1 2 YARSEIVGVSR 11 1 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 YARS(0.94)EIVGVS(0.06)R;Y(0.184)ARS(0.816)EIVGVSR 116.9 0.0058643 45738000.0 107855.0 68593.0 83815.0 60443.0 59500.9 69229.0 46013.1 46369.6 83122.0 45285.7 True False 106316.9679218152 68434.1771228414 76924.05423525626 64888.17985193721 56001.174045270316 66268.23705068119 48395.43317417258 48524.1008965473 73759.92504653557 53113.27290559777 2.001702439064156 1.2884571667137634 1.4483019032169075 1.2216942451892934 1.054372494513856 1.2476775281475259 0.911173997132307 0.9135965125476799 1.3887286738596332 1.0 15.696784812372966 -1.5228787454584103 0.61339878856476 1.0762068953938932 60.349200812462044 0.7149646728379196 0.16495232392017217 96.82690198138714 0.7154315712112451 0.07148571547258101 7721.886021625941 0.029999999987699172 1.5228787454584103 59.27299391706815 up YAS(ph)GSSASLGGPESAVA ddPTM_PC-9_AZD4547_30min_R2 1 YASGSSASLGGPESAVA 17 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 YAS(0.811)GS(0.166)S(0.024)ASLGGPESAVA 139.86 8.3476e-05 3975700.0 12230.0 12060.0 20190.0 26816.0 22869.0 17348.0 16235.0 17278.0 18509.0 18113.0 True False 16118.88560019705 15958.159153846147 19922.267408088363 20633.98550307001 19694.03409767419 16263.226817576504 17679.883548637597 14608.082108941653 19487.3479531276 17478.869383168123 0.9221926914631724 0.912997219901054 1.139791537504891 1.180510309376201 1.126733867388427 0.9304507323132546 1.0115004100701759 0.8357566950531141 1.1149089524001827 1.0 14.093324246993786 -6.772178116300308 24.997835924518842 0.9703192180063306 1.0599986691748722 0.1192854006016203 0.1044619923211505 460.37123792835007 1071653.924842651 0.039125600071944516 0.03485179318846635 1.6897477767406236e-07 6.772178116300308 0.08967945116854159 YAS(ph)GSSASLGGPESAVA ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YASGSSASLGGPESAVA 17 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 YAS(0.696)GS(0.186)S(0.052)AS(0.066)LGGPESAVA 60.901 0.033967000000000004 3107500.0 6105.2 8178.5 7444.8 8782.0 13528.0 12353.0 10623.0 11645.0 8939.7 11516.0 True False 7138.689776803519 8990.40743017648 7622.312266561225 8289.973011628152 10877.285511560556 11705.186933786337 9616.7125361402 11339.331088897388 9070.426200249198 13603.759639394168 0.5247585936560575 0.6608766744262221 0.5603092430777966 0.6093883772851885 0.7995793662850226 0.8604376469494589 0.7069157932114473 0.8335439164964823 0.6667587814461813 1.0 13.731717800402233 -6.242449203611331 5.132631257020967 0.8007800744185796 0.5900232332957558 0.5924734268797807 0.09020206888676162 0.1347072873214243 10.873341246276489 0.02571149522322317 0.03212819357052478 5.722038774248136e-07 6.242449203611331 -0.21075684112282378 YAS(ph)GSSASLGGPESAVA ddPTM_PC-9_Lapatinib_30min_R1 1 YASGSSASLGGPESAVA 17 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 YAS(0.45)GS(0.45)S(0.098)AS(0.001)LGGPESAVA 82.515 0.0044045 3282900.0 11524.0 8571.6 12020.0 10181.0 11381.0 11926.0 12513.0 10953.0 11010.0 12138.0 True False 11359.665646757221 8551.752986837537 11031.76199854179 10929.744702820382 10711.591955906903 11415.952780863847 13160.86191342077 11461.916365892364 9769.93785956013 14236.03712713165 0.7979513923230421 0.6007116243423698 0.7749180407458326 0.7677519105362549 0.752427930627709 0.8019052408276481 0.9244751046861373 0.8051339191893334 0.6862821283979488 1.0 13.797259980017433 -6.33180475090018 0.8890493756421038 0.8408347779984345 0.7056988156745198 0.2522333055699184 0.09123908770355078 0.9044009508675058 1.5445636192992533 0.046842154615855 0.07037637563573235 4.6579545769171774e-07 6.33180475090018 -0.13513596232391478 YASGS(ph)SASLGGPESAVA ddPTM_PC-9_AZD4547_30min_R2 1 YASGSSASLGGPESAVA 17 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 YAS(0.37)GS(0.54)S(0.09)ASLGGPESAVA 119.88 9.2991e-05 3517700.0 13541.0 14893.0 22281.0 29782.0 26317.0 19412.0 21217.0 28380.0 22913.0 25789.0 True False 17846.756329703043 19706.871001511656 21985.53938185323 22916.220027313208 22663.338814486513 18198.164571293237 23105.271897224764 23994.52310752196 24124.134402183405 24886.13495956067 0.7171365243620017 0.7918815450263698 0.8834453167428034 0.9208428735338564 0.9106813432987427 0.731257167931653 0.9284395481568447 0.9641723452240553 0.9693805181634072 1.0 14.603054563759137 -1.5323753307320103 0.16098072690020132 1.0181697994290424 2.8969444696651428e-12 0.5536766599467825 0.06366916736503626 56.180059953465744 0.5860814775151924 0.20771214541727348 13.571495695840387 0.02935111940958689 1.5323753307320103 -1.0181697994261454 YASGS(ph)SASLGGPESAVA ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YASGSSASLGGPESAVA 17 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 YAS(0.097)GS(0.761)S(0.141)AS(0.001)LGGPESAVA 115.24 0.000156 1857600.0 19403.0 18963.0 27468.0 24015.0 32498.0 31249.0 28737.0 25542.0 30493.0 22477.0 True False 22687.544673281576 20845.52131789897 28122.941292970092 22669.517407680498 26130.25018884498 29610.24742927946 26014.823322136952 24871.549563986027 30938.902437911634 26551.902172165905 0.8544602389001231 0.785085798476281 1.0591686091119714 0.8537812944883748 0.9841197071084822 1.1151836594336202 0.9797724906281114 0.9367144170205111 1.1652235774785498 1.0 14.696527598622172 -5.082669397097804 0.5744313116366856 1.0364433143494236 0.7182217953945703 0.39531783907290685 0.08879156032666216 2.9964861066045025 0.9569763855453047 0.049648605635000634 0.6063790075061211 8.266670031919975e-06 5.082669397097804 -0.3182215189548533 YASGSSAS(ph)LGGPESAVA ddPTM_PC-9_AZD4547_30min_R2 2 YASGSSASLGGPESAVA 17 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 YASGS(0.002)S(0.022)AS(0.975)LGGPESAVA;YAS(0.025)GS(0.007)S(0.029)AS(0.938)LGGPESAVA 124.51 4.0373e-05 12231300.0 30855.0 34507.0 47199.0 56623.0 37181.0 32865.0 36344.0 40650.0 34792.0 39125.0 True False 40666.24817613085 45660.712928836554 46573.11042072128 43569.44216662936 32019.059940776788 30809.946354602955 39578.545592342765 34368.47654407214 36631.03409072427 37755.24565872316 1.0771019355487923 1.209387255523972 1.2335533674367922 1.1539970514418534 0.8480691724324391 0.8160441235927828 1.0482926253506801 0.9102967268372542 0.9702236987633229 1.0 15.20438948385647 -6.199786140577058 6.909308363199042 0.9278814258859356 1.177738986411501 0.7073229854648166 0.07439656164230679 0.13974800992693384 13.283663043805793 0.022608618345596704 0.02920216840099568 6.312681230139929e-07 6.199786140577058 0.24985756052556551 YASGSSAS(ph)LGGPESAVA ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YASGSSASLGGPESAVA 17 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 YAS(0.009)GS(0.01)S(0.082)AS(0.899)LGGPESAVA 73.415 0.010695 4061300.0 17150.0 15939.0 12921.0 17054.0 20951.0 18629.0 15499.0 13970.0 15352.0 11602.0 True False 20053.15627205994 17521.31858281872 13229.085643165374 16098.519669813995 16845.801948011915 17652.062445519765 14030.82251695726 13603.302302438518 15576.493956869432 13705.350758618535 1.4631625724317652 1.2784290523758055 0.9652496952583527 1.1746156631336508 1.2291405192543885 1.2879686741632177 1.0237477875664038 0.9925541156897539 1.1365264728503384 1.0 13.742451630824702 -4.972255536987946 3.9735267792938793 1.1116948227123822 1.446425124881278 0.5506346751634124 0.10336140872614114 0.17299074255959487 5.981680376004199 0.028110490384560222 0.12565318124795655 1.0659687252990781e-05 4.972255536987946 0.3347303021688959 YASGSSAS(ph)LGGPESAVA ddPTM_PC-9_Lapatinib_30min_R1 2 YASGSSASLGGPESAVA 17 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 YAS(0.024)GS(0.004)S(0.024)AS(0.949)LGGPESAVA;YAS(0.01)GS(0.004)S(0.02)AS(0.966)LGGPESAVA 86.944 0.0029793000000000003 10724900.0 47167.0 48208.0 50998.0 36624.0 38135.0 41758.0 43626.0 46090.0 42224.0 33301.0 True False 46494.38993063156 48096.37733789066 46805.14129797289 39317.4511340825 35891.97427629468 39972.10768265239 45884.740816342586 48231.50965981732 37468.28848156832 39057.03347920671 1.1904229735057674 1.2314395911173424 1.1983793219444365 1.0066676250518214 0.9189631438701802 1.0234291783561302 1.1748137717825096 1.2348994627432455 0.9593224355228052 1.0 15.253294755108882 -5.723500439886814 9.544985837579839 1.0544648104006245 1.2096554023124169 0.39834955846122866 0.09035187406614685 0.4252332779708672 101.34808375546153 0.027188746364022166 0.04684538770544196 1.8901643166823084e-06 5.723500439886814 0.1551905919117924 YASICQQNGIVPIVEPEILPDGDHDLKR ddPTM_PC-9_AZD4547_30min_R2 2 YASICQQNGIVPIVEPEILPDGDHDLKR 28 1 P04075;H3BQN4;P04075-2;H3BPS8;P09972 P04075;P09972 ALDOA;ALDOC Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase;Fructose-bisphosphate aldolase C 0 ; 165.4 6.4342e-14 29630000.0 65764.0 57132.0 87704.0 128530.0 93517.0 83475.0 76723.0 96784.0 72484.0 87473.0 False True 86675.58402382316 75598.80172284725 86540.98765522447 98899.39426870483 80533.77877092137 78255.29505402362 83551.19836785496 81828.25667506717 76315.35626098122 84410.59689470891 1.026832971361872 0.8956079509442018 1.025238427862001 1.1716466641275949 0.9540719025050449 0.927079039040996 0.9898188313023548 0.96940739297386 0.904096867792258 1.0 16.365136505588225 YASICQQNGIVPIVEPEILPDGDHDLKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 YASICQQNGIVPIVEPEILPDGDHDLKR 28 1 P04075;H3BQN4;P04075-2;H3BPS8;P09972 P04075;P09972 ALDOA;ALDOC Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase;Fructose-bisphosphate aldolase C 0 ;; 173.25 2.9283e-18 30441300.0 81204.0 70749.8 76252.8 91806.0 103074.6 97310.0 100438.7 87476.2 83277.7 75699.8 False True 94950.23334789262 77773.37257486106 78070.95594235437 86662.40745906769 82877.87205720709 92206.89229553532 90924.41922278295 85180.0424386954 84495.47881657007 89423.57450071289 1.061803152893823 0.8697188969363 0.8730466924214932 0.9691226048940463 0.9268011541693224 1.0311251010749996 1.0167835465138793 0.9525457119589459 0.944890419426216 1.0 16.448367594982486 -6.733126993300026 24.868176261200862 0.9878352452682434 0.934075847496912 0.15600858873890422 0.05604591662944388 367.75749051424316 323018.5718719604 0.01879408697273059 0.018790638117571378 1.8487279480695636e-07 6.733126993300026 -0.05375939777133143 YASICQQNGIVPIVEPEILPDGDHDLKR ddPTM_PC-9_Lapatinib_30min_R1 2 YASICQQNGIVPIVEPEILPDGDHDLKR 28 1 P04075;H3BQN4;P04075-2;H3BPS8;P09972 P04075;P09972 ALDOA;ALDOC Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase;Fructose-bisphosphate aldolase C 0 ; 132.39 5.756100000000001e-11 19195900.0 73356.0 59157.0 70527.0 70916.0 69654.0 66982.0 59130.0 59053.0 60565.0 59258.0 False True 72309.92998815722 59020.02560109521 64728.54230209289 76131.39920884102 65557.08866503285 64117.33600266826 62191.462074687945 61796.817963575406 53743.53192227608 69500.66634367817 1.0404206720923703 0.8492008595895097 0.9313370030441535 1.09540531356022 0.9432584191474586 0.9225427521170869 0.894832601563178 0.8891543234706913 0.7732808151294025 1.0 16.084739189415977 -7.010580723508901 2.04687101768918 0.878500336848467 0.9698170683328455 0.19341871688075862 0.07958383550731622 0.5494038763149314 4.614440356570797 0.03563121329224345 0.027515523057034495 9.759313665254e-08 7.010580723508901 0.09131673148437858 YASS(ph)PKPNNSYMFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YASSPKPNNSYMFK 14 1 Q86VQ1;H7C0B2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 Y(0.036)AS(0.043)S(0.92)PKPNNSYMFK 66.289 0.044948 0.0 14866.0 16409.0 16908.0 18889.0 21929.0 19801.0 23515.0 22782.0 17117.0 22315.0 True False 17382.520183116227 18037.97707669693 17311.15084394707 17830.710568964267 17632.16986864365 18762.600702331678 21287.488966142966 22183.99663952429 17367.30374281748 26360.532854557212 0.6594145982944778 0.6842796834275117 0.6567071667124633 0.6764169247770608 0.6688851839956413 0.7117686431398521 0.8075515424363959 0.841561009480471 0.6588373550201212 1.0 14.686091912978016 -14.522878745067127 0.1304139804889081 1.9927478926739555 0.5882027896678533 0.743349709202564 0.05441701805686766 72.14518223641872 0.5906910546780944 18.603581010892544 0.41632505851390184 3.000000001472809e-15 14.522878745067127 -1.404545103006102 YASS(ph)PKPNNSYMFK ddPTM_PC-9_Lapatinib_30min_R1 1 YASSPKPNNSYMFK 14 1 Q86VQ1;H7C0B2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 Y(0.004)AS(0.203)S(0.786)PKPNNS(0.003)Y(0.003)MFK 65.51100000000001 0.018289 18140000.0 80895.0 68519.0 66999.0 74309.0 62988.0 80473.0 65532.0 73142.0 85059.0 64138.0 True False 79741.42246567404 68360.34846529475 61490.60084361901 79773.93174755716 59283.1696791727 77031.35738172526 68924.92630946146 76540.44433799858 75478.75970902137 75224.16784148698 1.0600505762151582 0.9087551305232684 0.8174314533221895 1.0604827416058291 0.7880867463245949 1.0240240549293467 0.9162604025703636 1.017498053275714 1.0033844424583183 1.0 16.198908621552057 -7.766087185599958 24.999134467711947 1.0078309551327531 0.9355405151207686 0.11137803060815543 0.08711988779402012 249.38178636709182 1341314.0290242822 0.04348063076123875 0.02197164502688299 1.713613261235811e-08 7.766087185599958 -0.07229044001198448 YAT(ph)SPKPNNSYMFK ddPTM_PC-9_Lapatinib_30min_R1 1 YATSPKPNNSYMFK 14 1 Q6P1L5 Q6P1L5 FAM117B Protein FAM117B 1 Y(0.152)AT(0.704)S(0.144)PKPNNSYMFK 63.76 0.031199 6048600.0 27748.0 24746.0 25901.0 25767.0 29075.0 32534.0 27859.0 26717.0 32240.0 25571.0 True False 27352.308431639995 24688.70215738972 23771.51976075131 27661.99113619221 27364.865663649354 31142.59666045817 29301.40270486608 27958.36935520372 28608.791697749184 29990.91327878427 0.9120198567273763 0.823206080051408 0.7926240704902912 0.9223457411602217 0.9124385579483972 1.0384010773852828 0.9770093505486559 0.9322280083741771 0.9539153220114572 1.0 14.872237835157616 -6.157498632641369 2.1061547582640987 0.9732266879883386 0.8430568761412659 0.6255533322120294 0.04338887035261897 0.2106686279650075 1.836847211575258 0.014624238781796261 0.020388856732704103 6.958271454808129e-07 6.157498632641369 -0.13016981184707266 YATSCYSCCPR ddPTM_PC-9_Lapatinib_30min_R1 1 YATSCYSCCPR 11 0 Q13057-2;K7EPC2;K7ES73;K7EN91;Q13057 Q13057-2 COASY Bifunctional coenzyme A synthase;Phosphopantetheine adenylyltransferase;Dephospho-CoA kinase 0 123.86 0.0025022 0.0 2987.9 2494.0 3424.0 2582.9 3417.0 3941.6 2081.4 1199.4 1214.4 2236.1 False True 2945.291998086247 2488.2252962309044 3142.491937022219 2772.8550823018154 3216.018778080474 3773.026956318374 2189.1647076315835 1255.1285026249705 1077.6214838010744 2622.6069055840408 1.1230398241593686 0.948760293024848 1.1982321598906958 1.0572896290320395 1.226267944018962 1.4386551595989718 0.8347284920856517 0.47858049178188217 0.410897066390929 1.0 11.356785867383564 -7.505343888003445 5.654614257970222 0.5931402854082246 1.1550944508652583 0.6252455387787192 0.18790319404221778 0.10427960690602868 11.364533658759889 0.08426320213531382 0.05253763977967937 3.1236050191147065e-08 7.505343888003445 0.5619541654570337 YAVEGRDLT(ph)LQY(ph)NIYNVGS(ph)RHVHEEK ddPTM_PC-9_Lapatinib_30min_R1 1 YAVEGRDLTLQYNIYNVGSRHVHEEK 26 2 E9PNP2 E9PNP2 SSR2 3 Y(0.63)AVEGRDLT(0.671)LQY(0.651)NIY(0.51)NVGS(0.538)RHVHEEK 41.482 0.043661 0.0 7712.4 6719.4 7775.9 5583.3 7554.0 6574.4 5580.2 7131.8 8203.7 6339.2 True False 7602.419761719059 6703.841642138703 7136.59551784202 5993.9145073428 7109.688571735414 6293.2282376749345 5869.115451871706 7463.169463915928 7279.712917209213 7434.922273546955 1.0225284787129587 0.9016693645864468 0.9598749328198944 0.8061838828724301 0.9562559378772924 0.8464416985320606 0.7893983603236441 1.0037992583284259 0.9791242799013558 1.0 12.860101944740117 -7.856170029891147 24.568750832002717 0.9936019180939846 0.8967780887163589 0.29975443178112926 0.06781038386083559 18.505810340700926 4788.740033041208 0.037186930253956016 0.0178640248639244 1.3926114772606224e-08 7.856170029891147 -0.09682382937762568 YCAGWADK ddPTM_PC-9_Lapatinib_30min_R1 2 YCAGWADK 8 0 P00352;Q5SYQ7;Q5SYQ9;Q5SYQ8 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ; 124.08 0.015285 129223000.0 523820.0 502430.0 524920.0 520250.0 527670.0 501100.0 568030.0 453860.0 497840.0 441270.0 False True 516350.23074317566 501266.6542042068 481763.1038497972 558510.9205031241 496633.4880391347 479669.12112115364 597439.8140078642 474947.9924973901 441768.0167123902 517542.93154468335 0.9976954553355644 0.9685508653515997 0.9308659716632668 1.0791586290941426 0.9595986299278761 0.9268199638810838 1.1543773039749896 0.9176977667917087 0.8535871901368033 1.0 18.98131901735335 -7.950132506089979 24.999946062587266 0.9130724341804862 0.9995810721614542 0.18952246090024494 0.07346449890088975 153.73087440414417 77069.16894651145 0.039063978864377485 0.018765722267800232 1.1216761713441631e-08 7.950132506089979 0.08650863798096797 YCDPDSYHR ddPTM_PC-9_AZD4547_30min_R2 1 YCDPDSYHR 9 0 P26368;P26368-2;K7ENG2 P26368 U2AF2 Splicing factor U2AF 65 kDa subunit 0 88.177 0.0086612 2901800.0 12404.0 13704.0 28967.0 35701.0 33002.0 30568.0 23672.0 33588.0 22516.0 27310.0 False True 16348.21398077221 18133.550003673932 28582.87865329842 27470.68602495162 28420.24195598601 28656.57812771953 25778.762141259576 28397.746375456223 23706.149792674958 26353.885212517063 0.6203341119892049 0.6880788110536812 1.0845793105193715 1.042377084191902 1.0784080497735304 1.0873758421816597 0.9781769152206702 1.0775544534119927 0.8995314960776813 1.0 14.685728045914415 -5.214705227909093 5.472074658809692 1.0361366642297163 0.6443634142349512 0.8712436267193044 0.057979175625658706 0.06084383897197368 4.441465078719842 0.014427701279631215 0.03896392758011107 6.0995075342047925e-06 5.214705227909093 -0.39177324999476504 YCDPDSYHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YCDPDSYHR 9 0 P26368;P26368-2;K7ENG2 P26368 U2AF2 Splicing factor U2AF 65 kDa subunit 0 66.568 0.040365 4494400.0 11055.0 12950.0 23794.0 26013.0 26823.0 18608.0 20330.0 19955.0 20237.0 17110.0 False True 12926.393153797242 14235.590416431547 24361.33919924751 24555.575945283887 21567.225700516625 17632.163722488156 18404.195223546107 19431.202394070206 20532.927840357388 20211.907557314516 0.6395434531422687 0.7043170159008475 1.2052963892777826 1.214906404833493 1.0670554295461159 0.8723651477471371 0.9105620125838041 0.9613739989147249 1.0158827306196885 1.0 14.302917866215573 -5.149034574429404 6.303956801254222 1.0268724815125596 0.658140332938675 0.6484256885407879 0.10598752664042567 0.16003189294236844 7.776434633582952 0.03131058759390931 0.08550025263954225 7.09521280324378e-06 5.149034574429404 -0.3687321485738846 YCHDLGER ddPTM_PC-9_AZD4547_30min_R2 3 YCHDLGER 8 0 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 0 ;; 118.74 0.0029289000000000003 5483300.0 38741.0 39532.0 49228.0 60474.0 46678.0 46668.0 43512.6 49986.0 43762.0 46930.0 False True 51059.83213714095 52309.945909605776 48575.20455499618 46532.65361398628 40197.565420929495 43749.8425825836 47385.13710492444 42261.812264009604 46075.16997810633 45286.99498438025 1.1274722943032935 1.1550765496286026 1.072608252584435 1.027505879558484 0.8876182982508305 0.9660575314761595 1.0463299037895504 0.9331997470484837 1.017404002937221 1.0 15.46680919217739 -5.680288322092507 2.2388076585156016 0.9746400322355825 1.139081461240266 0.6938679875391991 0.04341781273548169 0.16483804437492824 1.6741976061545953 0.012950128393036523 0.026481131320899232 2.087909536406299e-06 5.680288322092507 0.1644414290046835 YCHDLGER ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YCHDLGER 8 0 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 0 ;;; 127.46 0.0030328000000000004 5413200.0 38130.1 39870.9 42874.6 40670.4 47961.5 41390.8 46846.2 41177.1 40703.700000000004 35883.4 False True 44584.77282619666 43829.01945440159 43896.89306682595 38391.76934321583 38563.78836950851 39220.193583660934 42408.5887988827 40096.24475574379 41298.91460866509 42388.77636716192 1.0518060828180913 1.0339769913329089 1.0355782079341256 0.9057060060114751 0.9097641327382929 0.9252494868911657 1.0004673980571925 0.9459165418798424 0.9742889073028036 1.0 15.371394700400893 -5.738046527671445 21.201302755223765 0.9485656926197098 1.0398066494032496 0.6205677336994739 0.031764741053078006 27.909649553392978 25293.340962469232 0.009035363680614807 0.015622877756385945 1.827904375086331e-06 5.738046527671445 0.09124095678353983 YCHDLGER ddPTM_PC-9_Lapatinib_30min_R1 1 YCHDLGER 8 0 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 0 100.02 0.0042148 3262800.0 23571.0 24269.0 22911.0 23134.0 24918.0 22972.0 20045.0 20924.0 23678.0 16016.0 False True 23234.873217608005 24212.806621582906 21027.346019017557 24835.351532761713 23452.372230672892 21989.5411103475 21082.832019061727 21896.205426817465 21011.134299606256 18784.344260021444 1.2369275656355267 1.2889886538714481 1.1194080415024055 1.3221303437042822 1.248506304294389 1.1706312877339908 1.1223618843023515 1.1656624859361724 1.1185449972999095 1.0 14.197243133573986 -8.289255352505778 0.4033990609854194 0.9906089920236002 1.25707594300713 0.6454417265247078 0.054402029538647645 0.7606563557522932 0.3525670701795652 0.07646238947566388 0.047639797977124566 5.13741497725248e-09 8.289255352505778 0.2664669509835299 YDDAERR ddPTM_PC-9_AZD4547_30min_R2 2 YDDAERR 7 1 P29692-2;P29692;E9PRY8;A0A087X1X7;E9PK01;P29692-3;E9PI39;E9PQ49;P29692-4;E9PL71;E9PL12;E9PQZ1;E9PPR1;H0YCK7;E9PK06;E9PIZ1;E9PMW7;E9PN91;E9PK72;E9PKK3;E9PJD0;E9PNW6 P29692-2 EEF1D Elongation factor 1-delta 0 ; 68.78699999999999 0.030516 28103000.0 133605.0 98501.0 113317.0 139111.0 117879.0 101537.0 100586.0 88166.0 145382.0 186891.0 False True 176088.61084336258 130339.52195796004 111814.34253998757 107041.10819352523 101513.53558965151 95187.8753387288 109537.9591390985 74541.97055312827 153066.5957167646 180348.0029751934 0.9763823715174894 0.7227112017197553 0.6199921301893621 0.5935253311801216 0.5628758506608723 0.5278011054650921 0.6073699588132688 0.4133229607393069 0.8487290859429072 1.0 17.460423922437613 -8.501723733183265 8.168689460026018 0.9999743695178734 0.6237502117648313 0.44086868092926534 0.13875981853164565 0.17936844872683463 59.44960014744734 0.13895787513090438 0.0359146708601885 3.149751321497843e-09 8.501723733183265 -0.3762241577530422 YDDAERR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YDDAERR 7 1 P29692-2;P29692;E9PRY8;A0A087X1X7;E9PK01;P29692-3;E9PI39;E9PQ49;P29692-4;E9PL71;E9PL12;E9PQZ1;E9PPR1;H0YCK7;E9PK06;E9PIZ1;E9PMW7;E9PN91;E9PK72;E9PKK3;E9PJD0;E9PNW6 P29692-2 EEF1D Elongation factor 1-delta 0 72.138 0.025068 17855000.0 13464.0 20663.0 16901.0 15747.0 35099.0 32663.0 21776.0 24874.0 33162.0 28057.0 False True 15743.189273878437 22714.286082990347 17303.983937399422 14864.746642462827 28221.602910279704 30950.09478007473 19713.21963541268 24221.083856181507 33646.931513659714 33143.5120009102 0.47500063582417246 0.6853312974909406 0.5220926477835002 0.4484964249429754 0.8514970564828697 0.9338206156072043 0.594783667912782 0.7307941251221758 1.015189081734479 1.0 15.016438863154146 -6.823605257604201 0.26717758853355356 1.0382814564366636 0.39944732529709565 0.5368897481218857 0.13915404934246203 2.6658080389765395 0.42665194654422134 0.2574059052549108 0.5800623116489494 1.5010485606448273e-07 6.823605257604201 -0.638834131139568 YDDYRDYDS(ph)PER ddPTM_PC-9_Lapatinib_30min_R1 1 YDDYRDYDSPER 12 1 P52756;C9JR02;C9J9P7;C9JFQ5;F8W910;P52756-3;P52756-4;P52756-2;P52756-5 P52756 RBM5 RNA-binding protein 5 1 YDDYRDYDS(1)PER 126.83 0.0012162000000000002 4132100.0 10005.0 14055.0 13958.0 11192.0 10883.0 10858.0 12238.0 11141.0 11774.0 9926.2 True False 9862.326865307703 14022.456511036633 12810.427119438124 12015.097015417527 10242.883336801237 10393.628651234241 12871.623759006106 11658.651532220108 10447.888134283461 11641.930444169891 0.847138446033803 1.20447863679334 1.1003696664287663 1.0320536678205727 0.8798268797363175 0.8927753606739008 1.1056262379107433 1.001436281390823 0.897436055333556 1.0 13.507042682753763 -6.012642665845365 23.005222343792372 0.9655918452522069 1.0660718856538796 0.13010253487692403 0.10375262637143016 387.61778360274155 705334.7031196278 0.030205669907910418 0.04113222761329842 9.71308823972874e-07 6.012642665845365 0.10048004040167269 YDDYS(ph)SSRDGYGGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YDDYSSSRDGYGGSR 15 1 P38159;P38159-2;H3BUY5;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 YDDYS(0.68)S(0.16)S(0.16)RDGYGGSR 95.755 0.013403 9272000.0 28927.0 23648.0 31975.0 38551.0 32319.0 29934.0 28632.0 34685.0 28134.0 17466.0 True False 33823.769765707184 25995.617155812608 32737.405265862795 36391.112454028334 25986.323953882737 28364.208344204668 25919.769682271115 33774.55550179529 28545.40652570119 20632.447539220066 1.6393483953569654 1.259938604297805 1.5866951898766497 1.7637806850036934 1.2594881874525805 1.3747379359762024 1.256262478457799 1.6369631105371036 1.3835201311642469 1.0 14.332627351682719 -6.290161253007684 24.998313840819005 1.3500439535876074 1.5425659787992807 0.2710950562276965 0.19071119302907666 1215.9747967115409 1058329.6783725328 0.05918595455753487 0.06712188032286556 5.126709945373128e-07 6.290161253007684 0.19252202521167328 YDDYS(ph)SSRDGYGGSR ddPTM_PC-9_Lapatinib_30min_R1 1 YDDYSSSRDGYGGSR 15 1 P38159;P38159-2;H3BUY5;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 YDDYS(0.7)S(0.15)S(0.15)RDGYGGSR 107.73 0.0038994999999999998 11317000.0 39058.0 39566.0 53602.0 41490.0 35227.0 37763.0 34846.0 38331.0 39821.0 32728.0 True False 38501.02575764 39474.387357927786 49195.05046970356 44541.31300658263 33155.0171189467 36147.96451985254 36650.15537721251 40111.998194195185 35335.93964628011 38384.99119268122 1.0030229149819607 1.0283807845566024 1.2816220335380322 1.160383567186417 0.8637495043966115 0.9417213185851868 0.9548043190433378 1.0449917258765256 0.9205665690765492 1.0 15.22825469662604 -6.249459681761516 24.89815812867941 0.9559508823073731 1.1235879158501132 0.480280800766559 0.08351919982336387 674.9088484768915 1402705.0152185564 0.026473849631008725 0.03389437461473844 5.630413855765698e-07 6.249459681761516 0.16763703354274007 YDDYSS(ph)SR ddPTM_PC-9_AZD4547_30min_R2 1 YDDYSSSR 8 0 P38159;P38159-2;H3BUY5;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 1 YDDYS(0.09)S(0.893)S(0.016)R 93.598 0.007104899999999999 7468900.0 95778.0 97065.0 101760.0 143860.0 135250.0 111500.0 93710.0 148870.0 101450.0 100780.0 True False 126233.41169384061 128439.36304047047 100410.59591119709 110695.29961484375 116472.87208493738 104527.88737374787 102050.00845967517 125865.56219227579 106812.43988572007 97251.72287504448 1.298006944885015 1.3206898473716293 1.032481409508923 1.1382348439942034 1.1976432770717031 1.0748178467547798 1.0493388234447616 1.2942244977397088 1.0983089731269835 1.0 16.56943618811888 -5.245757473116711 24.49495001475503 1.1217645829577878 1.3093484488234426 0.4820321976003993 0.08174734583929626 544.8289668944373 851011.4131828708 0.02049788508296834 0.05380174527628676 5.678616328410236e-06 5.245757473116711 0.1875838658656548 YDDYSSSR ddPTM_PC-9_AZD4547_30min_R2 3 YDDYSSSR 8 0 P38159;P38159-2;H3BUY5;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 0 ;; 162.25 0.00010631 53196000.0 148858.0 147632.0 219246.0 287849.0 228957.0 192997.0 194045.0 223058.0 176293.0 199092.0 False True 196191.74756125367 195351.15689888995 216338.65478720854 221489.8602727176 197170.27263549724 180928.86708045978 211314.62908502558 188589.51146291895 185611.4880707072 192121.84967888833 1.0211839407603442 1.016808641106668 1.126049198197894 1.152861377521166 1.0262771931721812 0.941740189275002 1.0998989934680308 0.9816140734545638 0.9661133722215223 1.0 17.551662077931738 -6.509611358962037 24.37271326995846 1.0009794605829783 1.079544124140011 0.3307811151446214 0.05455802445372151 594.8134586136741 1092697.4946281451 0.018257938241548498 0.019787374608164134 3.093062110923687e-07 6.509611358962037 0.07856466355703273 YDDYSSSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YDDYSSSR 8 0 P38159;P38159-2;H3BUY5;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 0 ;;; 148.99 0.0037336999999999995 46460100.0 178013.0 206033.0 222367.0 240850.0 236765.0 213678.0 235082.0 224387.0 208068.0 168616.0 False True 208147.08498298633 226486.59461533962 227669.07261154414 227355.95534623583 190372.5978817736 202472.34952137907 212813.33111370658 218497.07900767925 211110.60087401667 199184.74603647803 1.0449951069288557 1.1370679689189735 1.1430045580390458 1.1414325638399971 0.9557589206500251 1.0165052974704145 1.068421831231658 1.0969568872892728 1.0598733340521698 1.0 17.603747641621077 -6.227026881535621 24.962428230437297 1.0387216106224568 1.1199695194228088 0.4469633854804633 0.04527845451006493 638.841153329442 463407.85939381947 0.014274411658127591 0.018427186777438716 5.928886254032265e-07 6.227026881535621 0.08124790880035193 YDDYSSSR ddPTM_PC-9_Lapatinib_30min_R1 4 YDDYSSSR 8 0 P38159;P38159-2;H3BUY5;Q96E39 P38159 RBMX;RBMXL1 RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1 0 ;;; 161.02 0.00012509 70763100.0 264579.0 212088.0 286600.0 222827.0 230313.0 222202.0 214598.0 215085.0 250335.0 202012.0 False True 260806.05494215374 211596.92326664788 263036.85430799297 239214.44090908152 216766.4421527796 212698.93843816099 225708.83440392144 225078.63430639647 222139.6361555846 236929.50503593052 1.1007749115189445 0.893079666184079 1.1101903676711908 1.0096439481980284 0.9148984720999895 0.8977309027252856 0.9526413114723409 0.949981448162242 0.9375769223925782 1.0 17.85409834426219 -6.166069843243785 5.590028909633193 0.9381428570520224 1.026171942322538 0.327648648623858 0.06065212351657242 0.2721241475121723 12.799044270079214 0.017250432461914426 0.022427701835209896 6.822289692479149e-07 6.166069843243785 0.08802908527051556 YDEELEGERPHSFR ddPTM_PC-9_AZD4547_30min_R2 1 YDEELEGERPHSFR 14 1 O43290 O43290 SART1 U4/U6.U5 tri-snRNP-associated protein 1 0 73.881 0.0087675 7011800.0 41722.0 40382.0 64835.0 72927.0 57599.0 56225.0 44769.0 59108.0 50566.0 55805.0 False True 54988.728128489056 53434.69178694983 63975.245537563525 56114.80686091833 49602.3730811114 52709.2418617846 48753.354270955104 49974.21676671627 53238.81552746497 53851.28393572002 1.0211219512263952 0.9922640256958876 1.1879985185483795 1.0420328497255549 0.9210991726830439 0.9787926676864636 0.9053331825690526 0.9280041832682832 0.9886266702761233 1.0 15.716693121823372 -6.158297464622104 5.321327939014323 0.9491754853262852 1.0675821950268418 0.4745598463657198 0.055416130469404815 0.19585961779071615 8.24053235764712 0.01677877258103656 0.021858988231159865 6.945484322920767e-07 6.158297464622104 0.11840670970055667 YDEELEGERPHSFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YDEELEGERPHSFR 14 1 O43290 O43290 SART1 U4/U6.U5 tri-snRNP-associated protein 1 0 ; 66.023 0.016934 9247200.0 71856.0 70945.0 79533.0 80704.0 87773.0 80037.0 83174.0 75810.0 74823.0 53994.0 False True 84019.80157930849 77987.95074082915 81429.36835058204 76182.41652589821 70574.51073375251 75839.71882291406 75295.15659238692 73820.06782733441 75917.14482379107 63782.68478373118 1.317282297918245 1.2227135155138729 1.2766688737967946 1.1944059235545035 1.1064838517389237 1.189033028008539 1.1804952527114723 1.1573684625794152 1.1902469311413335 1.0 15.960877205309181 -1.522910878685827 0.022486803674795865 4.7133852508319834e-08 2.751732121063637 0.7237919707573743 0.04353122385112364 1406.69563194282 2.444292577347119 106.8975850484324 207.5421378345683 0.029997780385101543 1.522910878685827 2.7517320739297846 YDEELEGERPHSFR ddPTM_PC-9_Lapatinib_30min_R1 1 YDEELEGERPHSFR 14 1 O43290 O43290 SART1 U4/U6.U5 tri-snRNP-associated protein 1 0 63.662 0.019668 5190200.0 37019.0 45950.0 56791.0 49328.0 52925.0 50975.0 42786.0 51321.0 51818.0 36649.0 False True 36491.10227154684 45843.605598159564 52121.86319959954 52955.74567338413 49812.05555455345 48794.918078528804 45001.24972649416 53705.561016521664 45981.71117226947 42983.73081827713 0.8489514887812029 1.0665338891119798 1.2125951425658188 1.2319950982678962 1.1588583542258004 1.1351950412312906 1.0469368030603607 1.2494392644410823 1.0697468622876627 1.0 15.391503087988323 -4.814365295275762 3.1716046154280466 1.1475999666090475 0.8163253319653501 0.5523872770962892 0.07772684225669496 0.2189352092138095 3.468865854261639 0.019124704086721317 0.17468682814920808 1.533326723168194e-05 4.814365295275762 -0.33127463464369744 YDEFHDYLER ddPTM_PC-9_AZD4547_30min_R2 1 YDEFHDYLER 10 0 Q96K76-2;Q96K76-4;Q96K76 Q96K76-2 USP47 Ubiquitin carboxyl-terminal hydrolase 47 0 100.82 0.0043872 0.0 5309.6 5881.9 7150.9 11207.0 8807.5 9661.2 5692.0 9859.1 7666.9 8559.4 False True 6997.9423534592215 7783.109148176418 7056.074393684945 8623.39929642398 7584.730653516359 9057.083636728741 6198.576973134906 8335.602634579627 8072.156681713432 8259.738011278592 0.847235389779143 0.9422949175323306 0.8542733902758106 1.0440281864447531 0.9182773888420532 1.0965340092338742 0.7504568504074596 1.009184870415677 0.9772896756157374 1.0 13.011880306521887 -5.737886890429648 24.99965673713885 0.9650736221923294 0.8873705976795907 0.1695680160966765 0.08989090882549775 475.50642779593335 504719.86337089486 0.02351070735356606 0.04069051951491108 1.8285763966325768e-06 5.737886890429648 -0.0777030245127387 YDEIFYNLAPADGKLS(ph)GSK ddPTM_PC-9_AZD4547_30min_R2 2 YDEIFYNLAPADGKLSGSK 19 1 Q9NZN4;Q9NZN4-2 Q9NZN4 EHD2 EH domain-containing protein 2 1 YDEIFY(0.004)NLAPADGKLS(0.819)GS(0.177)K;YDEIFY(0.001)NLAPADGKLS(0.699)GS(0.301)K 57.735 0.012163 20609000.0 24824.0 27914.0 43073.0 45721.0 49787.0 48335.0 46778.0 47770.0 48351.0 49144.0 True False 32717.51562872377 36936.65461197854 42501.82387660177 35180.729832408404 42874.93443617584 45312.60480905928 50941.151379006435 40388.244145395474 50906.73514947713 47423.483518269444 0.6899011460454958 0.7788684396781829 0.8962189346598367 0.7418419572416135 0.9040865675685482 0.9554887462369362 1.0741756530682072 0.8516507255279189 1.0734499318226127 1.0 15.533314020225687 -6.526807416404386 2.3779058357839187 0.9888059155905601 0.7843261220152653 0.6343249356571875 0.0763901325607555 0.20369943805415794 2.316905797944868 0.026715944683504814 0.028606255925114336 2.972984079885201e-07 6.526807416404386 -0.20447979357529478 YDEIFYNLAPADGKLS(ph)GSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YDEIFYNLAPADGKLSGSK 19 1 Q9NZN4;Q9NZN4-2 Q9NZN4 EHD2 EH domain-containing protein 2 1 YDEIFYNLAPADGKLS(0.864)GS(0.136)K 56.972 0.012969 6869300.0 23569.0 24270.0 25847.0 30432.0 31844.0 25101.0 32343.0 27420.0 24824.0 17957.0 True False 27558.76619103094 26679.365205157832 26463.29050529335 28726.993701875188 25604.396794066695 23784.65937221492 29279.236896957766 26700.25405389149 25187.00403760596 21212.461952466227 1.2991781082641787 1.2577212991562257 1.2475350840743238 1.354250806259445 1.2070450309559588 1.1212587876651272 1.3802847101184157 1.2587060433495432 1.187368259942955 1.0 14.372624451643256 -8.662419639380156 2.4991316515489683 1.0002996084441742 1.264496688655598 0.5801770883963346 0.06849792239354338 0.4004361233893327 5.021824804383192 0.06686334153727087 0.018074503029396803 2.1756065648483972e-09 8.662419639380156 0.26419708021142374 YDEIFYNLAPADGKLS(ph)GSK ddPTM_PC-9_Lapatinib_30min_R1 2 YDEIFYNLAPADGKLSGSK 19 1 Q9NZN4;Q9NZN4-2 Q9NZN4 EHD2 EH domain-containing protein 2 1 YDEIFYNLAPADGKLS(0.741)GS(0.259)K;YDEIFYNLAPADGKLS(0.767)GS(0.233)K 97.059 0.00029499 15184800.0 42271.0 44336.0 45738.0 49340.0 51487.0 45304.0 34591.0 48802.0 44295.0 40516.0 True False 41668.207788447966 44233.3427159957 41977.5981937857 52968.62819341501 48458.635887336655 43366.453528782105 36381.95272493712 51069.519080460064 39306.03065297148 47519.1366158235 0.876872156270886 0.9308532491574424 0.8833830154188341 1.114679936667386 1.019770966781419 0.9126103001278313 0.7656273938449928 1.074714793186169 0.8271621382927836 1.0 15.536221003327322 -6.891685477942325 14.490137093556756 0.9111094772943878 0.9669704040348764 0.053637633138158614 0.10192911498519058 2.2819749878210605 291.49100838720466 0.03633789931508555 0.03204792780876415 1.2832596005251418e-07 6.891685477942325 0.05586092674048859 YDERPGPS(ph)PLPHR ddPTM_PC-9_AZD4547_30min_R2 2 YDERPGPSPLPHR 13 1 P08621;P08621-4 P08621 SNRNP70 U1 small nuclear ribonucleoprotein 70 kDa 1 Y(0.001)DERPGPS(0.999)PLPHR;Y(0.002)DERPGPS(0.998)PLPHR 71.316 0.012353 273787000.0 56566.0 72449.0 89496.0 115750.0 95338.0 90466.0 76569.0 109089.0 81398.0 85483.0 True False 74552.81135410846 95866.72243258692 88309.22456435235 89065.62581967315 82101.96435366945 84809.14671886539 83383.49266619232 92231.8016658372 85700.53210268948 82490.26618900005 0.9037770733251672 1.1621579958651 1.070541151631394 1.0797107335744047 0.9952927556999158 1.028110959474326 1.0108282651815639 1.1180931511909242 1.0389169057393286 1.0 16.331936271642995 -6.204618442767298 24.984370535411376 1.0365375669532462 1.0629471329248426 0.01569519452912349 0.06778028933677649 1235.120430309841 543085.3735803613 0.01951001521656259 0.02518732035661657 6.242830697422267e-07 6.204618442767298 0.026409565971596383 YDERPGPS(ph)PLPHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 YDERPGPSPLPHR 13 1 P08621;P08621-4 P08621 SNRNP70 U1 small nuclear ribonucleoprotein 70 kDa 1 Y(0.004)DERPGPS(0.996)PLPHR;Y(0.066)DERPGPS(0.934)PLPHR;Y(0.003)DERPGPS(0.997)PLPHR;Y(0.114)DERPGPS(0.886)PLPHR;YDERPGPS(1)PLPHR;YDERPGPS(1)PLPHR;Y(0.033)DERPGPS(0.967)PLPHR 81.23899999999999 0.005594699999999999 1403022000.0 295117.0 317421.0 365660.0 373871.0 406054.0 320574.0 362254.0 304973.0 313949.0 259123.0 True False 345074.4792735571 348932.45911769225 374378.72117327247 352924.21997613553 326490.63358302764 303762.5351017263 327938.67862815905 296967.7818956031 318539.9101918448 306099.9486834612 1.1273261585234684 1.1399298190622185 1.223060385287482 1.152970529704647 1.0666144668996744 0.9923638877046922 1.071345095086185 0.9701660623363852 1.0406401946876764 1.0 18.22364327743918 -6.380195529386067 2.9332117366254096 1.0169936488742533 1.1650032882754393 0.7941353755767498 0.03501169354574592 0.11747930122361012 1.9428424465128056 0.011561195991808807 0.013390502760542105 4.166817415087621e-07 6.380195529386067 0.14800963940118605 YDGHLPIEIK ddPTM_PC-9_AZD4547_30min_R2 1 YDGHLPIEIK 10 0 P43490;A0A0C4DFS8 P43490 NAMPT Nicotinamide phosphoribosyltransferase 0 91.54899999999999 0.0067145 3227000.0 61383.0 56883.0 68366.0 83594.0 81500.0 76763.0 61377.0 71127.0 64009.0 71268.0 False True 80901.5171542843 75269.3173423075 67459.42217044918 64322.69481442549 70185.13179240214 71962.99747507638 66839.43409699589 60135.956485860246 67392.38506303659 68772.92901229083 1.1763570101809375 1.0944614170621652 0.9809008157612874 0.9352909020776182 1.0205342828987105 1.046385525650877 0.9718858140395708 0.8744131935272523 0.9799260556576337 1.0 16.06955317027147 -5.068237840364579 2.399097673209633 0.9732614078935519 1.1780850225852337 0.6886539576119803 0.04445454966701846 0.20939417359928872 2.1093857536546627 0.013166033909894717 0.06838976299216247 8.545985657863807e-06 5.068237840364579 0.20482361469168187 YDGHLPIEIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YDGHLPIEIK 10 0 P43490;A0A0C4DFS8 P43490 NAMPT Nicotinamide phosphoribosyltransferase 0 73.84100000000001 0.022580000000000003 5083900.0 64957.0 67435.0 57557.0 67985.0 74731.0 58616.0 75932.0 67130.0 63639.0 53198.0 False True 75952.9371407696 74129.50113761087 58929.37716613801 64176.02086034388 60087.99701097216 55542.0737724294 68739.17125992633 65367.90863011441 64569.59998184037 62842.37628486375 1.208626115544642 1.179610089879204 0.9377331133853347 1.0212220583358391 0.9561700330775842 0.8838315330511666 1.093834691233388 1.040188364835258 1.0274850156707496 1.0 15.939450114439529 -5.212336069489061 7.45819915646112 0.9956589204116387 1.1961194787236142 0.6707800329866125 0.05579065346946314 0.16885151861746536 22.360306596561802 0.01500675559139116 0.039893352596307906 6.132872422904649e-06 5.212336069489061 0.2004605583119755 YDGHLPIEIK ddPTM_PC-9_Lapatinib_30min_R1 2 YDGHLPIEIK 10 0 P43490;A0A0C4DFS8 P43490 NAMPT Nicotinamide phosphoribosyltransferase 0 ; 89.679 0.0077176 9978700.0 224000.0 203505.0 220580.0 210410.0 205060.0 201779.0 197108.0 189335.0 228260.0 196267.0 False True 220805.7189234306 203033.79667580957 202444.76386342358 225884.25330718406 192998.77396347164 193149.38253982257 207313.2877831489 198132.19530139992 202550.95511563995 230191.48944066075 0.9592262488068672 0.8820212996108532 0.8794624178128454 0.9812884649039685 0.8384270610196616 0.8390813361916798 0.9006123045074199 0.8607277175313419 0.8799237348340542 1.0 17.81247497007584 -4.757300216109787 24.745382726061024 0.8901322574320141 0.9592263640642235 0.11059442798753127 0.05188285402789021 221.63816198065942 1324827.5760748545 0.012449542101147081 0.09303320954044092 1.748637484604599e-05 4.757300216109787 0.06909410663220938 YDGIILPGK ddPTM_PC-9_Lapatinib_30min_R1 1 YDGIILPGK 9 0 Q5VVC8;P62913-2;P62913 Q5VVC8 RPL11 60S ribosomal protein L11 0 93.429 0.028858999999999996 82851000.0 86754.0 93982.0 91301.0 83246.0 85228.0 78002.0 88477.0 80881.0 74891.0 78569.0 False True 85516.87205126495 93764.39045323672 83794.58421205198 89368.1885405154 80215.0566046949 74666.0362915429 93057.90613871423 84639.02653060728 66455.98694280813 92149.54696338827 0.9280227073198901 1.017524160921703 0.9093325683450643 0.9698169061647376 0.8704878021436715 0.8102702482217117 1.0098574459154623 0.918496393305493 0.7211754059866579 1.0 16.491689452673157 -6.259772573679821 24.913212188782843 0.8864742979738878 0.957210413033229 0.13674957713502967 0.08334514563437664 298.4416814407042 4460701.168095833 0.02495019811141393 0.03050272485737623 5.498287264408571e-07 6.259772573679821 0.07073611505934119 YDGSTIVPGEQGAEYQHFIQQCTDDVR ddPTM_PC-9_AZD4547_30min_R2 2 YDGSTIVPGEQGAEYQHFIQQCTDDVR 27 0 Q14019 Q14019 COTL1 Coactosin-like protein 0 ; 106.67 4.4833e-10 14930300.0 36972.1 28885.1 59988.0 68999.0 57787.0 45940.0 61199.0 60993.0 56167.0 60412.0 False True 48728.458732546664 38221.64369608303 59192.519924537075 53092.34657392328 49764.272526227585 43067.36453766802 66645.59244182764 51567.93332970705 59135.87295279686 58296.99426798171 0.8358657139088499 0.655636610017738 1.0153614378888691 0.9107218517967921 0.8536335903952337 0.7387578910105453 1.1432080380588543 0.8845727636086644 1.0143897416213083 1.0 15.831133881046163 -1.949606348203035 0.18972339602869545 1.0270212244349097 3.47020613403277e-10 0.24568556452448853 0.11895771187698183 67.20307479361493 0.9039192738744909 0.24719989416477461 19.534033052330656 0.01123035931693053 1.949606348203035 -1.027021224087889 YDGSTIVPGEQGAEYQHFIQQCTDDVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YDGSTIVPGEQGAEYQHFIQQCTDDVR 27 0 Q14019 Q14019 COTL1 Coactosin-like protein 0 ; 116.44 5.5936e-12 13219500.0 40024.7 39328.3 50722.1 57478.3 70661.0 51315.1 58519.4 53854.3 51925.5 40529.9 False True 46800.091186141 43232.5537123201 51931.50722863543 54257.97719816289 56815.48429423266 48624.04582092928 52976.01878823333 52440.68168834754 52684.8122041052 47877.650035488135 0.977493489163557 0.902979859710638 1.0846711814414967 1.1332631647114153 1.1866807216335717 1.0155896495523045 1.1064874476705968 1.0953060906180059 1.10040514029101 1.0 15.547064722195353 -5.29736396770843 8.310587501176705 1.0967674869603006 0.9403157097602177 0.5569875311876351 0.05328828121075324 0.18725922681602297 40.80631126700283 0.01363910708101849 0.028915552414130647 5.042385349521154e-06 5.29736396770843 -0.15645177720008285 YDGSTIVPGEQGAEYQHFIQQCTDDVR ddPTM_PC-9_Lapatinib_30min_R1 3 YDGSTIVPGEQGAEYQHFIQQCTDDVR 27 0 Q14019 Q14019 COTL1 Coactosin-like protein 0 ;; 122.59 1.5613e-12 30021500.0 124556.0 162982.0 208492.0 163152.0 175852.0 189925.0 172676.0 165160.0 210184.0 170475.0 False True 122779.80859922683 162604.6251925846 191350.59256239384 175150.74233911705 165508.73109833422 181802.3504867992 181616.31836984307 172833.93654622303 186510.86458435832 199941.37660634116 0.6140790399826269 0.8132615067102001 0.9570334855658142 0.8760104852332107 0.8277862937004761 0.9092782773259815 0.9083478440154097 0.8644230597977267 0.9328277505639776 1.0 17.609217534051723 -4.825186764755831 2.9304483874824307 0.9002898101397284 0.5799099511898796 0.7845995884123497 0.0468727394806556 0.15363033431108916 2.0093292118326254 0.011596532913870552 0.112256656985612 1.4955923506394517e-05 4.825186764755831 -0.3203798589498488 YDHQAEEDLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YDHQAEEDLR 10 0 Q15417-3;Q15417 Q15417-3 CNN3 Calponin-3 0 77.062 0.0187 4770900.0 88384.0 112510.0 109020.0 105920.0 98866.0 78497.0 90808.0 78756.0 86872.0 79654.0 False True 103345.66553642829 123679.24924731406 111619.45026065236 99985.6457972733 79493.91701551946 74380.47913392914 82206.00884701304 76688.73844887964 88142.33865432272 94094.63965928297 1.0983161836916888 1.3144133363511148 1.1862466413052517 1.0626072447837804 0.844829389892636 0.7904858279202845 0.8736524114942286 0.8150170798949848 0.9367413380133709 1.0 16.521824918047997 -6.0266066316875495 2.5947047431285495 0.8628657264453009 1.2121620972275635 0.7875823860635598 0.07554679818506937 0.11214553368708383 1.5101612665310855 0.022617846784698817 0.03350732908656783 9.405748637157521e-07 6.0266066316875495 0.3492963707822626 YDHQAEEDLR ddPTM_PC-9_Lapatinib_30min_R1 2 YDHQAEEDLR 10 0 Q15417-3;Q15417 Q15417-3 CNN3 Calponin-3 0 ; 88.338 0.0084367 9368800.0 91455.0 118174.0 136649.0 124624.0 126895.0 115315.0 131600.0 124173.0 125512.0 103604.0 False True 90150.83492920687 117900.37536358916 125414.24670039388 133789.2646934772 119431.28558516888 110383.24626239426 138413.6040762545 129942.53089582353 111375.51686004638 121511.81335634753 0.7419100451149475 0.9702791202517289 1.032115670371917 1.1010391582349661 0.9828779794020747 0.9084157598626443 1.1390958644518003 1.0693818757749252 0.9165818020789857 1.0 16.890737053635192 -4.758192095018521 2.9718964087870225 1.0226734844789584 0.6858445809880875 0.5847743953530665 0.06958774784037913 0.30483928434004526 3.6829274645027112 0.018168693084731312 0.2554413616846086 1.74505012012829e-05 4.758192095018521 -0.3368289034908709 YDIDLPNKK ddPTM_PC-9_AZD4547_30min_R2 1 YDIDLPNKK 9 1 E5RGN3;E5RIM7;O00244 E5RGN3 ATOX1 Copper transport protein ATOX1 0 66.27 0.03094 6929300.0 38530.0 40145.0 47313.0 62842.0 51030.0 53174.0 53141.0 58500.0 46819.0 48817.0 False True 50781.73852621361 53121.08617173742 46685.59870623497 48354.74779922155 43945.36534191764 49849.02137409576 57870.44605224213 49460.16919626619 49293.7567571171 47107.931688738354 1.0779870120757926 1.1276463276445774 0.9910347797629088 1.026467222520433 0.9328655232049434 1.0581874344105984 1.2284650159258992 1.049932939596458 1.0464003616805213 1.0 15.52368237027094 -7.004114770935279 24.998050053971504 1.0936414521544489 1.0302101963145935 0.08415469186181457 0.07340940125033026 373.12855562466217 2266843.412125795 0.02729449414151103 0.023492382101726394 9.90570132484671e-08 7.004114770935279 -0.06343125583985532 YDIPATAATATS(ph)PTPNPVPSVPANPPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YDIPATAATATSPTPNPVPSVPANPPK 27 0 P51610;A6NEM2;P51610-4;P51610-3 P51610 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 YDIPATAAT(0.011)AT(0.124)S(0.432)PT(0.432)PNPVPSVPANPPK 82.21600000000001 6.4688e-06 7148200.0 69800.0 75743.0 80837.0 79500.0 83389.0 71568.0 72189.0 69559.0 56953.0 57739.0 True False 81615.7613871593 83262.26447195181 82764.46065602949 75045.87274247753 67049.5240629453 67814.84809173651 65350.735316899634 67733.14995385252 57785.82988050964 68206.6236383275 1.1965958294598353 1.220735758941219 1.2134372915876381 1.10027250638319 0.9830353781838281 0.9942560483763511 0.9581288712285262 0.9930582447976664 0.8472172759485184 1.0 16.057624227686873 -6.0796223335522095 1.7617666618086216 0.9572743253128417 1.2170772332783037 0.8792505405218677 0.04152046150646013 0.11070935062425602 0.6851328263613166 0.013697731674174485 0.021070158759581688 8.324873950637605e-07 6.0796223335522095 0.259802907965462 YDIPATAATATS(ph)PTPNPVPSVPANPPK ddPTM_PC-9_Lapatinib_30min_R1 2 YDIPATAATATSPTPNPVPSVPANPPK 27 0 P51610;A6NEM2;P51610-4;P51610-3 P51610 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 YDIPATAAT(0.005)AT(0.054)S(0.726)PT(0.214)PNPVPSVPANPPK;YDIPATAAT(0.003)AT(0.321)S(0.582)PT(0.094)PNPVPSVPANPPK 90.1 2.1851e-07 10447100.0 65748.0 99101.0 100360.0 96758.0 113959.0 110328.0 88585.0 103255.0 110479.0 96985.0 True False 64810.42146329349 98871.53772324712 92108.78820080333 103873.90609522608 107256.1556720142 105609.52862712937 93171.49785026605 108052.60425090986 98035.69162455431 113748.72802561069 0.5697683181890292 0.8692100513070006 0.809756643433102 0.9131874078788706 0.9429218025881161 0.9284457985618199 0.8190992503167891 0.9499236266323933 0.8618618715673149 1.0 16.795490887164377 -4.3499512480456355 1.4469039661731484 0.9049495319349417 1.821921546062601e-19 0.7554204307795599 0.05642728535749838 1.7248261441914785 1.4320194389542615 0.015270753977908695 3.064709305325784 4.4673373766588545e-05 4.3499512480456355 -0.9049495319349417 YDLANQDHMMDAPPLS(ph)PFPHIK ddPTM_PC-9_AZD4547_30min_R2 2 YDLANQDHMMDAPPLSPFPHIK 22 0 P28749;P28749-2 P28749 RBL1 Retinoblastoma-like protein 1 1 YDLANQDHMMDAPPLS(1)PFPHIK;YDLANQDHMMDAPPLS(1)PFPHIK 71.872 0.00057856 11402600.0 71098.0 74540.0 98449.0 139703.0 113618.0 109840.0 97009.0 106731.0 93791.0 104243.0 True False 93705.68506973097 98633.59729085342 97143.50193456614 107496.63173983409 97844.10188943775 102971.68743616554 105642.61306866536 90238.17638438795 98748.60078187841 100593.48429909955 0.9315283760438325 0.9805167598885559 0.9657037193952304 1.0686242005516886 0.9726683847485894 1.0236417214657239 1.0501933977607634 0.8970578662538256 0.9816600097901406 1.0 16.618177335506623 -4.680671224889282 1.6606690466428804 0.9961086371066564 0.8979080699688965 0.1534442097415165 0.04513429374202578 2.6343379108028118 5.887173810338001 0.01286807572023053 0.4507834141364145 2.086069508253807e-05 4.680671224889282 -0.09820056713775993 YDLANQDHMMDAPPLS(ph)PFPHIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YDLANQDHMMDAPPLSPFPHIK 22 0 P28749;P28749-2 P28749 RBL1 Retinoblastoma-like protein 1 1 YDLANQDHMMDAPPLS(1)PFPHIK;YDLANQDHMMDAPPLS(1)PFPHIK;Y(0.001)DLANQDHMMDAPPLS(0.999)PFPHIK;YDLANQDHMMDAPPLS(1)PFPHIK 72.158 0.00031739 25913700.0 89479.0 76203.0 94540.0 115091.0 124678.0 122872.0 125336.0 126692.0 102637.0 92267.0 True False 104626.02740919271 83767.93023191752 96794.19214494656 108642.82440005615 100248.24090851152 116428.37601620621 113463.26672594079 123366.46924127011 104137.87195487296 108994.27671482999 0.9599222139244407 0.768553475987422 0.8880667413225427 0.9967754975273301 0.9197569260521689 1.068206327207681 1.041002061262385 1.1318619010064463 0.9554434883524828 1.0 16.733892855568236 -6.134817200903851 1.1379676605482953 1.045067257035114 0.858147260826445 0.47596258380973766 0.06964019815525746 0.3848968147809229 1.024134060844423 0.027553469389530922 0.04695507346892958 7.331330515851319e-07 6.134817200903851 -0.18691999620866906 YDLDFKSPDDPSR ddPTM_PC-9_AZD4547_30min_R2 1 YDLDFKSPDDPSR 13 1 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 67.252 0.046096 13309000.0 122350.0 57925.0 129950.0 253840.0 211530.0 127050.0 108760.0 130190.0 105830.0 164140.0 False True 161254.7549619063 76648.12346488703 128226.77809217853 195321.1097889056 182162.71077358082 119105.54341555758 118439.42930396223 110072.12696857913 111423.95774377296 158393.50856032767 1.0180641645455366 0.48390949958466195 0.8095456641983565 1.2331383499502016 1.1500642446101264 0.751959752000781 0.7477543138003787 0.6949282705399239 0.7034629054973845 1.0 17.273153685108582 YDS(ph)SNQVK ddPTM_PC-9_AZD4547_30min_R2 1 YDSSNQVK 8 0 A0A087WZ12;A0A087WT34;A0A087X1H1;A0A0A0MTS6;K7EIE8;O95983-2;O95983 A0A087WZ12 MBD3 Methyl-CpG-binding domain protein 3 1 Y(0.004)DS(0.965)S(0.031)NQVK 85.81299999999999 0.012944999999999998 24902000.0 87546.0 79196.0 102670.0 154210.0 114620.0 111410.0 104320.0 116240.0 105220.0 128170.0 True False 115383.80693007784 104794.55823781076 101308.52871661383 118659.26702074967 98706.99148521674 104443.51508797561 113604.27790538176 98277.77892946963 110781.71438911259 123682.80731191198 0.9329009377923875 0.847284764272309 0.8190995249738056 0.9593836815290455 0.7980655810656895 0.8444465108605 0.9185130930840414 0.7945953125208892 0.8956921078750703 1.0 16.91628544500407 -11.417732465462416 4.6253986937002916 1.0440417085614266 0.8650392061831609 0.34608917109939774 0.0544083576679415 0.025420021814758147 0.000577857060704592 0.054193437046415896 0.012069954628638427 3.821796290316223e-12 11.417732465462416 -0.17900250237826576 YDS(ph)SNQVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 YDSSNQVK 8 0 A0A087WZ12;A0A087WT34;A0A087X1H1;A0A0A0MTS6;K7EIE8;O95983-2;O95983 A0A087WZ12 MBD3 Methyl-CpG-binding domain protein 3 1 Y(0.053)DS(0.932)S(0.015)NQVK;Y(0.002)DS(0.906)S(0.092)NQVK;Y(0.017)DS(0.971)S(0.011)NQVK 87.29799999999999 0.01183 32490700.0 97554.0 119065.0 106191.0 122057.0 166720.0 171479.0 180122.0 191428.0 168905.0 141296.0 True False 114067.96542067271 130884.98632682799 108722.99617161002 115218.54200413314 134052.412809534 162486.3393684731 163059.54018964898 186403.21783473142 171374.91608813367 166911.84630147967 0.6834024543389255 0.7841563629367612 0.6513797467390797 0.690295773231236 0.8031330057149193 0.9734859626139829 0.976920115634737 1.1167764419671329 1.0267390834476344 1.0 17.348726825745437 -6.737620550435415 1.822422709262354 1.0410916295801331 0.7027052048493185 0.9147035152109031 0.04629339022266128 0.09150674004572262 0.6276697421673233 0.019215065652698027 0.017883937592426572 1.82969815252908e-07 6.737620550435415 -0.3383864247308146 YDS(ph)SNQVK ddPTM_PC-9_Lapatinib_30min_R1 1 YDSSNQVK 8 0 A0A087WZ12;A0A087WT34;A0A087X1H1;A0A0A0MTS6;K7EIE8;O95983-2;O95983 A0A087WZ12 MBD3 Methyl-CpG-binding domain protein 3 1 Y(0.05)DS(0.941)S(0.009)NQVK 88.441 0.010973 25407000.0 78766.0 78343.0 103030.0 94025.0 131640.0 151600.0 117210.0 170550.0 181930.0 139090.0 True False 77642.78239608457 78161.60159687951 94559.27110730117 100939.91215820504 123897.19401419775 145116.42139686047 123278.56028706548 178474.37562338568 161439.1275921685 163131.52117422485 0.47595205290314124 0.47913242661056743 0.5796505201855603 0.6187639974888788 0.7594926665452673 0.8895670214579547 0.7557004274814779 1.094052052838854 0.9896255881764942 1.0 17.31567604893263 -6.448549766306482 0.5673409190177876 1.0365858045486178 0.41963060747051506 0.8933795539479698 0.06931260932870717 0.2889506368566408 0.19848050577943985 0.053895223812653596 0.08875941914600907 3.560001932250468e-07 6.448549766306482 -0.6169551970781028 down YDSYESCDSR ddPTM_PC-9_Lapatinib_30min_R1 1 YDSYESCDSR 10 0 V9GZ50;Q9ULX6;M0R1Y5;M0R010;M0QYT7 V9GZ50 AKAP8L A-kinase anchor protein 8-like 0 152.06 0.0007751 2233900.0 12724.0 14694.0 27363.0 11954.0 18038.0 21413.0 21927.0 21784.0 18065.0 15490.0 False True 12542.553426704178 14659.976945796676 25113.31976423451 12833.137037374998 16977.040304072463 20497.215906140995 23062.27277036502 22796.16416640183 16030.329467116604 18167.425860872394 0.6903869333364043 0.8069374856990724 1.3823268060403455 0.7063816930176124 0.93447692777634 1.1282399643796717 1.2694298546738407 1.254782286768455 0.8823665823588963 1.0 14.149066398414924 -6.748197638669914 5.857403603836073 1.1338674634474828 0.9130044676697964 0.18466986784004868 0.20930200494856496 0.2803375881465916 32.29995207233374 0.07279753477679068 0.06949598592407391 1.7856747653059263e-07 6.748197638669914 -0.22086299577768642 YEAVS(ph)PERLELER ddPTM_PC-9_AZD4547_30min_R2 3 YEAVSPERLELER 13 1 Q92585 Q92585 MAML1 Mastermind-like protein 1 1 YEAVS(1)PERLELER;Y(0.001)EAVS(0.999)PERLELER;Y(0.005)EAVS(0.995)PERLELER 71.316 0.012353 33172400.0 28646.3 24585.0 43959.1 51583.9 40434.3 37629.3 29587.3 41112.3 28777.4 35196.3 True False 37755.22751994481 32531.620464121686 43376.17361163431 39692.02881831045 34820.69539182247 35276.33392244821 32220.512381805045 34759.33870166931 30298.51461377351 33964.08824991995 1.1116219944468493 0.9578240471153634 1.2771187406079285 1.1686469698889679 1.0252209667929046 1.038636269664367 0.9486641344444448 1.0234144501656461 0.8920750173190626 1.0 15.051722505781237 -6.653731759825558 1.9884159791384217 0.9729164624177857 1.1242658758778554 0.41515033561749715 0.0826467759734718 0.35076717968054777 2.8432015604023095 0.03306544591965778 0.03270424516273116 2.2195669027553746e-07 6.653731759825558 0.1513494134600697 YEAVS(ph)PERLELER ddPTM_PC-9_Lapatinib_30min_R1 1 YEAVSPERLELER 13 1 Q92585 Q92585 MAML1 Mastermind-like protein 1 1 Y(0.006)EAVS(0.994)PERLELER 60.968 0.026095999999999998 12952000.0 18519.0 17279.0 18305.0 13802.0 16385.0 18624.0 14458.0 11195.0 15110.0 12054.0 True False 18254.915664031338 17238.991537118603 16800.033559343377 14817.045122122283 15421.266514149429 17827.49493466444 15206.564496462686 11715.160569356796 13408.152684646106 14137.5178390546 1.2912390896231098 1.2193789414359744 1.1883297867843272 1.0480655296639487 1.0908043894062152 1.261006008099693 1.0756177052845066 0.8286575269241329 0.9484092495789014 1.0 13.78724122419244 -7.563173020808649 5.4198906470850385 0.9190376860596778 1.174564694120008 0.680224247884816 0.07882339583526583 0.11429570555222451 8.262111703663695 0.03970046770691502 0.022834308718498068 2.734179225594157e-08 7.563173020808649 0.25552700806033024 YEDDGIS(ph)DDEIEGK ddPTM_PC-9_AZD4547_30min_R2 1 YEDDGISDDEIEGK 14 0 I3VM54;Q9Y2K7;Q9Y2K7-3 I3VM54 KDM2A Lysine-specific demethylase 2A 1 YEDDGIS(1)DDEIEGK 115.8 0.0018569000000000003 0.0 1172.5 3115.0 1529.8 3765.8 2974.6 3174.5 2562.6 4231.6 2707.9 3363.7 True False 1545.3306104849592 4121.862832854952 1509.5138524464367 2897.6529910300205 2561.628135333493 2975.9980131655875 2790.666435585998 3577.7034524943597 2851.034065712585 3245.9378868305976 0.4760813867556328 1.2698526517029647 0.46504705421839043 0.8927013060805518 0.7891796530446615 0.9168376342750708 0.859741169696523 1.1022094621741838 0.8783390702822089 1.0 11.664419677887823 -7.1033725527977545 1.266792907330252 0.9863086782108766 0.7899853459885116 0.1380577472481327 0.21951075873912787 0.978214723264383 3.1465275273982236 0.1213665845852754 0.08020353659969748 7.881836963496598e-08 7.1033725527977545 -0.1963233322223651 YEDDGIS(ph)DDEIEGK ddPTM_PC-9_Lapatinib_30min_R1 1 YEDDGISDDEIEGK 14 0 I3VM54;Q9Y2K7;Q9Y2K7-3 I3VM54 KDM2A Lysine-specific demethylase 2A 1 YEDDGIS(1)DDEIEGK 130.27 0.00039632 0.0 2610.0 3805.7 2592.3 2939.0 4062.0 4176.3 4395.6 3220.3 2851.1 3100.3 True False 2572.7809213846194 3796.888135471511 2379.171100567377 3155.143864216591 3823.0811461992653 3997.689384430795 4623.182660164021 3369.926894283135 2529.979094586003 3636.182724109923 0.7075499546064186 1.0441961869231766 0.6543046048792167 0.8677077318739304 1.0513996232505318 1.0994192777837815 1.2714384867156805 0.9267760038401361 0.6957788666149334 1.0 11.828208983793552 -6.15745643087308 4.7988924670662705 1.0211700877775254 0.8174707146210802 0.23875348620785652 0.1660422480751004 0.35110970119338736 12.859866306896032 0.051860157916488854 0.06777001358203837 6.958947644904576e-07 6.15745643087308 -0.20369937315644515 YEDFKEEGSENAVK ddPTM_PC-9_Lapatinib_30min_R1 1 YEDFKEEGSENAVK 14 1 J3KQ32;Q9NTK5;Q9NTK5-2 J3KQ32 OLA1 Obg-like ATPase 1 0 69.846 0.037286 6329100.0 42042.0 65231.0 113970.0 102810.0 94377.0 84397.0 63205.0 58589.0 105570.0 72742.0 False True 41442.47337044146 65079.961627280674 104599.82653692267 110370.99036410628 88825.93041232099 80787.537049016 66477.44563555981 61311.25882966014 93679.59489861607 85315.35777737784 0.4857563098848109 0.7628164884111549 1.22603748330829 1.293682558914055 1.0411481909752245 0.9469284212559156 0.7791967046428647 0.718642697246209 1.098039055794197 1.0 16.380517846707527 -10.040072660065144 24.373461780132068 0.9999999999999941 0.9360351845897612 0.0073190350415703875 0.23538037783163093 0.0 0.0 0.24748794950943875 0.060024644523232154 9.11858267249524e-11 10.040072660065144 -0.06396481541023291 YEDKPEPEVDALGS(ph)PPALLK ddPTM_PC-9_AZD4547_30min_R2 4 YEDKPEPEVDALGSPPALLK 20 1 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 YEDKPEPEVDALGS(1)PPALLK;YEDKPEPEVDALGS(1)PPALLK;YEDKPEPEVDALGS(1)PPALLK;YEDKPEPEVDALGS(1)PPALLK 154.33 7.398300000000001e-06 95575400.0 186346.0 181568.0 212055.0 219005.0 220018.0 223618.0 208506.0 233287.0 209013.0 213990.0 True False 245600.1517624135 240256.30524424015 209243.0121457243 168516.7808435207 189472.29848712587 209635.131109801 227062.63007035587 197237.85455195492 220061.00047150368 206498.27523348638 1.1893569158614756 1.1634785083438772 1.0132918151937804 0.8160687088208354 0.9175490607507044 1.0151907122360602 1.0995860852281574 0.9551549732264797 1.0656796054237354 1.0 17.6557702060937 -5.280321773024204 4.193820388766338 0.9788750956747115 1.1813024350917487 0.5177112944671389 0.07425330060819667 0.16566693151776954 7.092583401366151 0.02141329661443737 0.05299690127939031 5.244187692859506e-06 5.280321773024204 0.20242733941703717 YEDKPEPEVDALGS(ph)PPALLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 YEDKPEPEVDALGSPPALLK 20 1 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 YEDKPEPEVDALGS(1)PPALLK;YEDKPEPEVDALGS(1)PPALLK;YEDKPEPEVDALGS(1)PPALLK;YEDKPEPEVDALGS(1)PPALLK;YEDKPEPEVDALGS(1)PPALLK 129.04 6.8316e-06 79115900.0 145663.0 145827.0 144726.0 173588.0 198016.0 185724.0 237729.0 200555.0 192317.0 167679.0 True False 170320.86892461055 160303.74082293196 148176.81671641118 163862.4271398891 159216.18626974992 175984.30649158356 215209.58811108614 195290.64375558755 195129.27229698125 198077.8753537661 0.8598682140568114 0.8092965483228769 0.7480735364904744 0.8272626452966118 0.8038060080430012 0.8884601885863146 1.086489784518957 0.9859286071541278 0.9851139202118425 1.0 17.59570821937917 -7.030406109884409 4.007052255581395 1.0126418600423925 0.8087384612162712 0.8677310519503261 0.03762014135095375 0.0765186780730476 2.7017506677006624 0.014941846856182077 0.011972456366975625 9.323820202050954e-08 7.030406109884409 -0.2039033988261213 YEDKPEPEVDALGS(ph)PPALLK ddPTM_PC-9_Lapatinib_30min_R1 4 YEDKPEPEVDALGSPPALLK 20 1 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 YEDKPEPEVDALGS(1)PPALLK;YEDKPEPEVDALGS(1)PPALLK;YEDKPEPEVDALGS(1)PPALLK;YEDKPEPEVDALGS(1)PPALLK 161.68 1.9752e-06 64922900.0 147276.0 139182.0 147982.0 153990.0 203991.0 209813.0 211311.0 206776.0 221221.0 184800.0 True False 145175.8172328896 138859.7326303168 135815.49118703936 165314.93829558103 191992.65044173662 200839.78708799122 222251.64962733633 216383.5678329004 196304.76141959615 216742.43376947875 0.6698080053271643 0.6406670360544358 0.6266216025399481 0.7627253021962714 0.8858101623327469 0.9266288266449885 1.025418261491504 0.9983442746750734 0.9057052557985966 1.0 17.725622105928778 -6.242632681659827 1.4810207323047204 0.9784291813706001 0.6396458682408984 0.9432408458843412 0.0352565407255013 0.08599146409695443 0.37733532786923163 0.013456279900969047 0.018835741370319303 5.719621873247312e-07 6.242632681659827 -0.33878331312970167 YEDRYDR ddPTM_PC-9_Lapatinib_30min_R1 1 YEDRYDR 7 1 E7EX17;P23588-2;P23588;F8VX11;F8VP89 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 79.45100000000001 0.042654000000000004 0.0 93697.0 138480.0 64112.0 116040.0 200230.0 77877.0 260600.0 259890.0 108590.0 137840.0 False True 92360.86359807463 138159.35806818557 58840.95883947683 124573.96869809226 188452.8650673261 74546.38225015372 274092.5928744067 271965.4381750902 96359.45069660619 161665.4603397448 0.5713085739153899 0.8546003443026082 0.3639674097102794 0.7705663809467794 1.165696523371701 0.4611150835403695 1.6954307512463882 1.6822729951317161 0.5960422869183307 1.0 17.3026519558503 -7.252854627701453 24.994094327371805 1.3002925973101076 0.7143906185353687 0.34609797383292695 0.36360644245509655 680.3801675512942 1980897.9540939687 0.1398200406789611 0.10655134973400622 5.5865716392150725e-08 7.252854627701453 -0.5859019787747389 YEEIDNAPEER ddPTM_PC-9_AZD4547_30min_R2 2 YEEIDNAPEER 11 0 P49411 P49411 TUFM Elongation factor Tu, mitochondrial 0 ; 181.4 0.0035729 13613800.0 35390.0 43577.0 54853.0 66997.0 56202.0 45665.0 44003.0 62833.0 45409.0 44738.0 False True 46643.283842270954 57662.41305531948 54125.6133796865 51551.87674333162 48399.32241713609 42809.56033114084 47919.18175489379 53123.60360870075 47809.22703568915 43171.7362371874 1.0804125084525376 1.3356519352967338 1.2537279733740156 1.1941117322709323 1.121088161736839 0.9916108098118467 1.1099665181780904 1.2305181176137407 1.1074196037199704 1.0 15.397799494364346 -6.189362513135175 3.1769476522182454 1.0997065684741922 1.2327506120427303 0.3302062082141216 0.08574432175847876 0.314398603095325 6.228978182407804 0.027359762289717537 0.03581732307921684 6.466026599716495e-07 6.189362513135175 0.13304404356853805 YEEIDNAPEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YEEIDNAPEER 11 0 P49411 P49411 TUFM Elongation factor Tu, mitochondrial 0 ; 145.28 0.00091782 5334100.0 70035.0 57950.0 70179.0 74057.0 88215.0 80599.0 80246.0 71621.0 68350.0 55654.0 False True 81890.5422456979 63702.89302179218 71852.33351533968 69907.82638603353 70929.90400667605 76372.2465535697 72644.51794927109 69741.02463872205 69349.4894445039 65743.62964317844 1.2456042158024485 0.9689591731934745 1.092917046188597 1.0633399276166549 1.0788863406484546 1.1616676318006436 1.1049666461001166 1.0608027730935963 1.0548472881843631 1.0 16.004563487985635 -8.455579520616384 1.4821972787735005 1.0022271766470947 1.0956514209027066 0.17957227499240125 0.06704706196147893 0.724507755598531 3.4628867415454208 0.06108820055717099 0.01820190006835751 3.502841443565412e-09 8.455579520616384 0.09342424425561191 YEEIDNAPEER ddPTM_PC-9_Lapatinib_30min_R1 2 YEEIDNAPEER 11 0 P49411 P49411 TUFM Elongation factor Tu, mitochondrial 0 ; 166.29 0.00027784 9440800.0 51809.0 49154.0 40760.0 44698.0 42125.0 35772.0 23616.0 28676.0 43917.0 29701.0 False True 51070.194159392995 49040.186933012745 37408.870138150014 47985.24002815694 39647.29032093651 34242.11494860485 24838.72092602454 30008.391646884797 38970.604993487956 34834.77827590519 1.4660691609660008 1.4077938589014436 1.0738943087812127 1.3775095580656465 1.1381525097393852 0.9829864475494515 0.7130437498207127 0.8614491933666548 1.1187269425062902 1.0 15.088240760086334 -6.61040019265283 2.344142683706241 0.9063966444789502 1.319468918585537 0.6454017628134161 0.13794459199838832 0.19288875631083394 2.1558881051913144 0.05252892507994247 0.05333759747716612 2.4524479981669883e-07 6.61040019265283 0.41307227410658687 YEEQERS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 YEEQERSPR 9 1 Q9HCG8;B7WP74 Q9HCG8 CWC22 Pre-mRNA-splicing factor CWC22 homolog 1 YEEQERS(1)PR;YEEQERS(1)PR 68.846 0.019797 17694000.0 38922.0 40100.0 33993.0 33566.0 41002.0 41925.0 37496.0 43614.0 45634.0 29013.0 True False 38366.96514257937 40007.15091373665 31198.22675677462 36034.55561289356 38590.34297303358 40131.96548194843 39437.35941066296 45640.46566073493 40494.21837267639 34027.85839260754 1.1275163044323264 1.1757175680038712 0.9168436754618784 1.0589721867633601 1.1340808618569198 1.1793855792778012 1.1589727145223638 1.3412676499985143 1.1900313532947362 1.0 15.05442873497843 -6.569715701548149 2.4765007520203217 1.1960357802823507 1.0674399845370242 0.1788261659022864 0.0996722675265751 0.422688411219036 5.252969374838131 0.03618418772700331 0.03764135295855265 2.693297316973445e-07 6.569715701548149 -0.12859579574532654 YEILT(ph)PNSIPK ddPTM_PC-9_AZD4547_30min_R2 2 YEILTPNSIPK 11 0 P35579;P35579-2 P35579 MYH9 Myosin-9 1 YEILT(0.981)PNS(0.019)IPK;YEILT(0.953)PNS(0.047)IPK 126.83 0.00095564 5097000.0 43256.0 42856.0 47739.0 55363.0 57226.0 58788.0 48920.0 56689.0 46892.0 49056.0 True False 57010.5082193069 56708.363905242986 47105.949667891546 42599.91569982342 49281.1576926627 55111.977066617925 53273.785229402594 47929.01763362622 49370.61538808464 47338.5643714843 1.2043142620871021 1.1979316368834125 0.9950861479075002 0.8998987667966681 1.041036168860849 1.1642088812438967 1.12537813380529 1.0124729862424302 1.0429259113278981 1.0 15.530728333920543 -5.250678506604389 23.99829197568141 1.0387862837795174 1.2011230068107168 0.48517957134781364 0.06831380295982047 405.4674338386542 904242.3310883429 0.01977985940616277 0.051098903936569 5.6146345448081045e-06 5.250678506604389 0.1623367230311994 YEILT(ph)PNSIPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YEILTPNSIPK 11 0 P35579;P35579-2 P35579 MYH9 Myosin-9 1 YEILT(0.999)PNS(0.001)IPK 142.83 0.00035428 2373000.0 23185.0 28695.0 24005.0 23586.0 29898.0 22142.0 26722.0 21105.0 18593.0 20095.0 True False 27109.762575376677 31543.64996135162 24577.37023946945 22264.55288684371 24039.701524588814 20980.834541236705 24190.69870947364 20551.016112595917 18864.88745049982 23738.06442806752 1.142037618843199 1.3288214823469304 1.0353569607136774 0.9379262135845604 1.012706895182433 0.8838477376626079 1.0190678680975747 0.8657410200764606 0.7947104325908843 1.0 14.534914683784905 -5.468378996722883 3.759807295223513 0.9317853051259444 1.2336591860480597 0.6970881910086426 0.07928949113011576 0.12013477483659472 3.397231650951257 0.021434105230763365 0.0461880976955775 3.4011125451808183e-06 5.468378996722883 0.3018738809221153 YEILT(ph)PNSIPK ddPTM_PC-9_Lapatinib_30min_R1 2 YEILTPNSIPK 11 0 P35579;P35579-2 P35579 MYH9 Myosin-9 1 YEILT(0.738)PNS(0.262)IPK;YEILT(0.947)PNS(0.053)IPK 118.76 0.0025236 4279100.0 44809.0 51451.0 50537.0 49482.0 56646.0 53684.0 50995.0 56229.0 57149.0 43579.0 True False 44170.01544303578 51331.86837064003 46382.04293846144 53121.07134711312 53314.193650320936 51388.06046351622 53635.2715795487 58841.604614056545 50712.27781435078 51111.57208463255 0.8641881601664948 1.0043101058531854 0.9074665686600332 1.0393159353258232 1.0430943810932132 1.0054095064504347 1.0493762839213263 1.1512384028537472 0.992187791257514 1.0 15.641362345840083 -4.79912006242891 0.5701198745106573 1.0558677430426717 0.7844492358786531 0.46221156628800064 0.05463751264882143 3.3533569443699105 0.8407380749774215 0.029218397168770185 0.6045219461061845 1.5881076492581847e-05 4.79912006242891 -0.2714185071640186 YEILTPNS(ph)IPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YEILTPNSIPK 11 0 P35579;P35579-2 P35579 MYH9 Myosin-9 1 YEILT(0.162)PNS(0.838)IPK 85.845 0.011241 2062800.0 24509.0 27542.0 23754.0 30477.0 31600.0 24568.0 28649.0 21730.0 22709.0 21949.0 True False 28657.88962518469 30276.187741263166 24320.38544754667 28769.472497767154 25408.206842498035 23279.6108305078 25935.159319201786 21159.610524838165 23041.076163792844 25928.179951811595 1.1052796485694851 1.1676942923696338 0.9379904602925054 1.1095831852153217 0.9799456379013125 0.8978497863627046 1.0002691807679198 0.8160854546737959 0.8886499633454978 1.0 14.662233318226097 -5.994670547279832 0.6670101944905362 0.900693189032236 1.1427579556453349 0.4970076686577999 0.0747831465971973 0.7918000321718476 0.6758734232443366 0.04381636838310917 0.11753405896964636 1.0123471224112481e-06 5.994670547279832 0.24206476661309884 YELHLK ddPTM_PC-9_AZD4547_30min_R2 2 YELHLK 6 0 Q02790 Q02790 FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed 0 ; 83.287 0.037096 20101200.0 286110.0 248060.0 377340.0 439240.0 397150.0 361780.0 359100.0 428240.0 328950.0 355760.0 False True 377087.02854230395 328240.54392231157 372336.22505042405 337980.00419035205 342012.57780800766 339157.83940874046 391059.2043311226 362065.3479762227 346337.625435265 343304.95068491675 1.0984025362581857 0.95611945958673 1.0845641005397328 0.9844891648549167 0.9962354959509593 0.9879200364926212 1.13910155839854 1.0546464513659872 1.0088337635221918 1.0 18.389131136500637 YELHLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YELHLK 6 0 Q02790 Q02790 FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed 0 84.359 0.03556 6442700.0 144190.0 151860.0 147970.0 164080.0 181560.0 157410.0 167350.0 155850.0 156330.0 119410.0 False True 168598.5191176861 166935.65719222333 151498.16597935004 154887.12955453768 145984.62133936546 149155.14249553223 151497.39649092176 151759.10263672486 158616.03050269617 141058.0877509599 1.1952417745471584 1.1834532840608945 1.0740126170349213 1.098037921994187 1.0349255662468884 1.0574022721679581 1.0740071619175258 1.0758624695427443 1.1244731374973342 1.0 17.10592986154917 -5.25118165810367 4.016061008916345 1.0691465643338083 1.1935177979471887 0.7032264699071209 0.03173675366550446 0.1093880423622665 4.19891247152075 0.00811900462676512 0.021662199572454296 5.60813348140279e-06 5.25118165810367 0.12437123361338043 YELHLK ddPTM_PC-9_Lapatinib_30min_R1 1 YELHLK 6 0 Q02790 Q02790 FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed 0 79.454 0.044407999999999996 10163000.0 209500.0 210240.0 238580.0 205910.0 236870.0 247580.0 218890.0 193180.0 241700.0 206580.0 False True 206512.49158240505 209753.20219710754 218964.87334543263 221053.30829562427 222937.77230433805 236991.58053716854 230223.05316300437 202155.8480382626 214477.20078616586 242287.07774945284 0.852346288958745 0.8657217881591344 0.9037414433297284 0.9123611145461655 0.9201389293030157 0.9781437076154745 0.9502077258989281 0.8343649604264507 0.8852193141227079 1.0 17.88635793591643 -5.288869996854461 1.6124609584774245 0.9224769276077612 0.8487087985313677 0.2694560784578264 0.04368817649491375 0.7552933472980096 3.324109389490787 0.013750152840804296 0.06371256616602972 5.141975501410868e-06 5.288869996854461 -0.07376812907639352 YELISETGGSHDKR ddPTM_PC-9_AZD4547_30min_R2 2 YELISETGGSHDKR 14 1 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3;Q96SI9-2;Q96SI9 Q12906-7 ILF3;STRBP Interleukin enhancer-binding factor 3;Spermatid perinuclear RNA-binding protein 0 ; 69.846 0.011414 9373400.0 37891.0 41985.0 82388.0 113875.0 91749.0 88622.0 60726.0 105613.0 74651.0 82613.0 False True 49939.54981823927 55555.83018857629 81295.48128863718 87622.87810121177 79011.2350530199 83080.45233037046 66130.49635815015 89292.93759530343 78596.89945696304 79720.74401544008 0.6264310554924967 0.6968804779069347 1.0197531682957213 1.0991226836046741 0.9911000709892677 1.042143464118695 0.8295268336349468 1.1200715534969097 0.9859027336942644 1.0 16.28266755413155 -5.219252644279566 4.415908771868776 1.0131373577120772 0.6470882312270421 0.7783719116716117 0.07480461088686269 0.0890229697915394 3.9679680075748784 0.019209672269650833 0.0532097587495603 6.03597393522476e-06 5.219252644279566 -0.3660491264850352 YELISETGGSHDKR ddPTM_PC-9_Lapatinib_30min_R1 1 YELISETGGSHDKR 14 1 Q12906-7;Q12906;Q12906-4;Q12906-6;Q12906-5;Q12906-2;Q12906-3;Q96SI9-2;Q96SI9 Q12906-7 ILF3;STRBP Interleukin enhancer-binding factor 3;Spermatid perinuclear RNA-binding protein 0 76.32600000000001 0.0065218 4487200.0 37083.0 50061.0 87090.0 60581.0 70381.0 69000.0 56767.0 70966.0 81229.0 52382.0 False True 36554.18961981066 49945.08683023869 79929.79637712165 65036.32883229172 66241.3279543699 66049.03084685601 59706.11749693577 74263.33943412015 72080.13464070934 61436.15890537234 0.5949947111132651 0.8129591387242668 1.3010220332985714 1.0586001792928588 1.0782140214266778 1.0750839900096731 0.9718400134503643 1.2087887777701891 1.1732526239430348 1.0 15.906800398645624 -5.036026933358148 4.538422781025938 1.1063241830274189 0.6312654631839913 0.7603290782600707 0.09438140308056756 0.0833042812790392 4.036739497834116 0.024245058656529914 0.08100235414291175 9.203924906013158e-06 5.036026933358148 -0.4750587198434275 YEPQS(ph)PGYEPR ddPTM_PC-9_AZD4547_30min_R2 4 YEPQSPGYEPR 11 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 YEPQS(1)PGYEPR;YEPQS(0.999)PGY(0.001)EPR;YEPQS(1)PGYEPR;YEPQS(1)PGYEPR 161.21 6.7623e-05 237782500.0 133696.0 108575.0 160033.0 212628.0 187402.0 164027.0 136145.0 176597.0 124704.0 165575.0 True False 176208.54695044496 143669.7454501531 157910.85785629536 163609.89966985263 161384.4670939849 153770.36576012342 148261.64125218787 149307.99144535046 131295.59885173832 159778.2696471075 1.1028317388818019 0.8991820087141242 0.9883124795697402 1.0239809207547925 1.0100526651742123 0.9623984919835885 0.9279211846494789 0.9344699487303118 0.8217362670263165 1.0 17.285711684929694 -7.172223073340275 1.979396349799223 0.911076546646393 0.9990194980930074 0.2845614327252862 0.06181037533195729 0.4449824919968196 3.4184028169793543 0.029081183110576222 0.019810786283702007 6.726310737165676e-08 7.172223073340275 0.08794295144661435 YEPQS(ph)PGYEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YEPQSPGYEPR 11 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 YEPQS(1)PGYEPR;YEPQS(1)PGYEPR;YEPQS(0.998)PGY(0.002)EPR;YEPQS(1)PGYEPR 145.61 5.7041000000000005e-05 180778000.0 84213.0 77691.0 79689.0 108717.0 120988.0 99897.0 103231.0 98292.0 83500.0 77826.0 True False 98468.59761743332 85403.64903806815 81589.08798221547 102625.93895526939 97281.2699196249 94658.2254613822 93452.21235228184 95711.93914898254 84721.02953351974 91935.23772972295 1.0710648065861053 0.9289544591067814 0.8874626312717682 1.1162851316812346 1.0581499795064278 1.0296185423446063 1.0165004698961957 1.0410800201590011 0.921529455143065 1.0 16.488330315644824 -5.753513297286067 24.999998918141117 1.028951660859326 0.9591400481202462 0.17494524433348124 0.06303648059013721 295.8566286580671 933162.6295081041 0.017361504155841746 0.029383173238470808 1.7639517547407213e-06 5.753513297286067 -0.06981161273907988 YEPQS(ph)PGYEPR ddPTM_PC-9_Lapatinib_30min_R1 3 YEPQSPGYEPR 11 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 YEPQS(1)PGYEPR;YEPQS(1)PGYEPR;YEPQS(0.999)PGY(0.001)EPR 160.46 0.00072838 213684400.0 98007.0 90263.0 86259.0 87842.0 101584.0 93633.0 95734.0 86658.0 91587.0 77759.0 True False 96609.4022077174 90054.00156924233 79167.11798936904 94302.19371232201 95609.02884182833 89628.53485918375 100690.63808994056 90684.44704058241 81271.50760613394 91199.53954264554 1.0593189690671867 0.9874392131895848 0.8680648870200705 1.034020502573104 1.0483499074808473 0.9827739844812794 1.1040695884528773 0.9943520273825257 0.8911394510728952 1.0 16.476738919934874 -4.758649399166578 23.960391609567477 0.9925706082390836 1.059319114396989 0.08976245694864682 0.06575110364928297 131.09132363098098 1125434.8657358019 0.01694901909317953 0.11364769802077142 1.7432135813518585e-05 4.758649399166578 0.06674850615790529 YEQGTGCWQGPNR ddPTM_PC-9_AZD4547_30min_R2 1 YEQGTGCWQGPNR 13 0 K7ELL7;P14314-2;P14314;A0A0C4DGP4 K7ELL7 PRKCSH Glucosidase 2 subunit beta 0 168.02 3.6731e-18 0.0 5786.5 6348.3 2756.3 7704.3 7720.5 5182.3 2756.2 6546.0 5331.1 5877.0 False True 7626.486633323 8400.26382722732 2719.7496610655717 5928.1926652484435 6648.641840530576 4858.249961766584 3001.4964605331043 5534.466112115527 5612.891062343641 5671.248018819581 1.3447633762471887 1.4812019857625198 0.4795681042409538 1.0453065437406743 1.172341928702041 0.8566456528871373 0.5292479628069305 0.9758815156293368 0.9897100327331326 1.0 12.469450535250509 -5.2355139012408545 24.98829122522541 0.8830545824700775 1.4129828474008146 0.5061285362391577 0.2101587700244161 625.1090594753767 602509.7737075549 0.05476009326801495 0.14477758364856722 5.814148216256877e-06 5.2355139012408545 0.5299282649307371 YEQGTGCWQGPNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YEQGTGCWQGPNR 13 0 K7ELL7;P14314-2;P14314;A0A0C4DGP4 K7ELL7 PRKCSH Glucosidase 2 subunit beta 0 170.4 2.4423e-18 0.0 6424.4 6308.3 4913.2 5190.2 4700.1 4729.7 4000.8 2542.6 4133.0 4145.2 False True 7511.924032316149 6934.546333897695 5030.349321414764 4899.409920855436 3779.1491449501596 4481.66620583901 3621.8152607163415 2475.859444107384 4193.437306132188 4896.691946614855 1.5340813990778484 1.4161696119543798 1.0272954427717897 1.0005550633509752 0.7717759634772886 0.9152436491205543 0.7396453156952518 0.5056187873568353 0.8563816862180117 1.0 12.257591722883495 -5.183694846638916 0.8272074528477458 0.7584791345544206 1.782888824914961 0.8001402976923306 0.1300189014913733 0.6086234031654596 0.47670354300171125 0.0512614504419185 0.5117881713653925 6.550963102996423e-06 5.183694846638916 1.0244096903605404 YEQGTGCWQGPNR ddPTM_PC-9_Lapatinib_30min_R1 1 YEQGTGCWQGPNR 13 0 K7ELL7;P14314-2;P14314;A0A0C4DGP4 K7ELL7 PRKCSH Glucosidase 2 subunit beta 0 185.3 1.639e-35 0.0 6196.3 5625.0 6643.0 5169.0 5902.6 3530.1 4997.9 5864.1 5137.4 5011.1 False True 6107.939625737745 5611.975658098966 6096.838182721558 5549.145503278516 5555.420672958097 3379.125852065023 5256.666807087484 6136.567493949546 4558.771912779673 5877.261958128967 1.0392491723615829 0.954862263768407 1.037360292285235 0.9441718852778671 0.9452395881851541 0.5749489943001913 0.894407437432132 1.044120125607457 0.7756625355918222 1.0 12.520928487441884 -6.536508089307119 24.99952916697342 0.8514518824264298 0.9880353713955708 0.21508953693284605 0.12300849922772288 379.11238973348173 695379.5073546517 0.041462487039077955 0.041481226246352365 2.907313806388458e-07 6.536508089307119 0.13658348896914108 YES(ph)QEPLAGQESPLPLATR ddPTM_PC-9_Lapatinib_30min_R1 1 YESQEPLAGQESPLPLATR 19 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 YES(1)QEPLAGQESPLPLATR 116.73 0.0005953999999999999 0.0 4382.2 4726.8 4231.4 2841.8 4032.8 5318.4 4732.5 4253.6 4551.1 4357.3 True False 4319.709024402943 4715.855385013726 3883.510625676351 3050.795451966897 3795.5986327898595 5090.944429795928 4977.5256936996575 4451.237784530242 4038.507192792382 5110.453499262704 0.8452692163280924 0.9227860865369565 0.7599150694232192 0.5969715706066089 0.7427126835881509 0.99618251697827 0.973989039214969 0.8710064156091883 0.79024438699521 1.0 12.319235605591535 -6.750315062616563 24.999580369918913 0.9212039119453175 0.7712575689692082 0.38219462138872906 0.09697669219461817 270.7273045491118 608402.0356836581 0.03589533552808614 0.03557382098648259 1.7769898099857375e-07 6.750315062616563 -0.14994634297610931 YESGPDGGEEDGT(ph)GSLKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YESGPDGGEEDGTGSLKR 18 1 Q07866-6;G3V5R9;G3V3H3 Q07866-6 KLC1 Kinesin light chain 1 1 YESGPDGGEEDGT(0.546)GS(0.454)LKR 55.621 0.033288 6627700.0 15942.0 17992.0 15532.0 30359.0 24812.0 32422.0 24768.0 23901.0 20172.0 21393.0 True False 18640.6657311475 19778.12685501439 15902.341785438015 28658.083655205977 19950.26671443231 30721.73324433098 22421.795735208547 23273.6240752028 20466.977338325305 25271.381553105184 0.7376195754069114 0.7826294266284062 0.6292628581473036 1.1340133342130105 0.7894410787359961 1.2156728819820335 0.8872406001267272 0.9209478328794845 0.8098875518663702 1.0 14.625216916223545 -5.7496101652998135 24.99999462892251 0.9618713559147194 0.7231164896885718 0.4356415636201135 0.1296681939255886 212.25466337669886 448577.37234674476 0.03392449796813244 0.058162146831709095 1.779876359289047e-06 5.7496101652998135 -0.2387548662261476 YESGPDGGEEDGTGS(ph)LKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YESGPDGGEEDGTGSLKR 18 1 Q07866-6;G3V5R9;G3V3H3 Q07866-6 KLC1 Kinesin light chain 1 1 YESGPDGGEEDGT(0.274)GS(0.726)LKR 79.942 0.0017421 5580400.0 14381.0 14921.0 21349.0 26824.0 29407.0 21903.0 23048.0 21846.0 23017.0 22019.0 True False 16815.419262302858 16402.25827054634 21858.04112653338 25321.138244581347 23644.90944991582 20754.368121972166 20864.726586930174 21272.56564775032 23353.58008111411 26010.87039769191 0.6464766078644943 0.6305924415355898 0.8403425488011722 0.9734829268469322 0.9090395318725653 0.7979113272508488 0.8021541097210503 0.8178336719419415 0.897839238904762 1.0 14.66682705631684 -5.3004040902421625 4.7476118951499116 0.8736704260007968 0.636397885369653 0.688850968569686 0.06500704858011488 0.11044424767178897 6.084055340891169 0.01804621539700707 0.0414716428315908 5.007211197612126e-06 5.3004040902421625 -0.23727254063114378 YESGPDGGEEDGTGS(ph)LKR ddPTM_PC-9_Lapatinib_30min_R1 3 YESGPDGGEEDGTGSLKR 18 1 Q07866-6;G3V5R9;G3V3H3 Q07866-6 KLC1 Kinesin light chain 1 1 YESGPDGGEEDGT(0.037)GS(0.963)LKR;YESGPDGGEEDGT(0.058)GS(0.942)LKR;YESGPDGGEEDGT(0.098)GS(0.902)LKR 71.946 0.0039062 25303400.0 82770.0 72664.0 78442.0 70547.0 76927.0 63567.0 53912.0 57471.0 64672.0 56029.0 True False 81589.68462184096 72495.75097246269 71992.80155487658 75735.26171789317 72402.30510430106 60848.38759191447 56703.29956655805 60141.31246820048 57387.95833364876 65713.53799605032 1.2415962845699293 1.1032087631139265 1.095555097934366 1.1525062266841453 1.1017867445921534 0.9259642601433472 0.8628861159471611 0.9152042988739283 0.8733049548648262 1.0 16.003902998008225 -6.736921096148819 3.5833151822163725 0.9036671801771636 1.1399295036468045 0.8296911647120617 0.0508615761309671 0.08767088661873837 2.3732443808659194 0.017553665055526253 0.016638208446396113 1.8326473526866272e-07 6.736921096148819 0.23626232346964082 YESLTDPSK ddPTM_PC-9_Lapatinib_30min_R1 2 YESLTDPSK 9 0 P07900;P07900-2;G3V2J8;Q58FF6;P08238;Q58FF7;Q58FF8 P07900;P08238 HSP90AA1;HSP90AB4P;HSP90AB1;HSP90AB3P;HSP90AB2P Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-beta 4;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3;Putative heat shock protein HSP 90-beta 2 0 ; 145.72 0.002199 57827000.0 406430.0 428420.0 446350.0 432250.0 425620.0 356810.0 523140.0 426200.0 365270.0 426800.0 False True 400634.2336698669 427428.01981204614 409652.8259608254 464039.1069437297 400585.8684011159 341550.06806473463 550225.6294563214 446002.8079195946 324129.4461363788 500571.8113247472 0.8003531653322653 0.8538795236608941 0.8183697457447561 0.9270180550432217 0.80025654529163 0.6823198197294277 1.0991941955344366 0.8909866633106296 0.6475183755924662 1.0 18.93321752533714 -7.226783808063763 24.99989120372432 0.9003407154865769 0.8202779706472825 0.1279730792562236 0.12076333050381405 1612.9726078303006 1163570.4051436589 0.04669793545034091 0.036170000290870766 5.932205564791788e-08 7.226783808063763 -0.08006274483929443 YESLTDPSKLDSGK ddPTM_PC-9_AZD4547_30min_R2 2 YESLTDPSKLDSGK 14 1 P07900;P07900-2;G3V2J8;P08238;Q58FF7;Q58FF8 P07900;P08238 HSP90AA1;HSP90AB1;HSP90AB3P;HSP90AB2P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3;Putative heat shock protein HSP 90-beta 2 0 ; 94.68799999999999 0.0043863 51481000.0 517820.0 416990.0 590260.0 734900.0 705840.0 607230.0 558700.0 624000.0 548780.0 615820.0 False True 682475.9886749013 551773.8628161117 582432.7667309669 565480.1590918159 607846.2996852663 569259.812107273 608423.2176546865 527575.1380935048 577787.3904434253 594260.3292410212 1.148446152457371 0.9285052958538011 0.9800970013846284 0.9515697603675434 1.0228619845137517 0.9579300251025028 1.0238328014117213 0.8877845485114486 0.9722799285312637 1.0 19.180735549281486 -4.753534363557839 24.999923661944415 0.968708128404713 1.1484464777990615 0.6479581877003504 0.03958258427153588 176.8089689404754 559120.4174363896 0.009474379115974265 0.10163580826697591 1.7638661930139057e-05 4.753534363557839 0.17973834939434852 YESLTDPSKLDSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YESLTDPSKLDSGK 14 1 P07900;P07900-2;G3V2J8;P08238;Q58FF7;Q58FF8 P07900;P08238 HSP90AA1;HSP90AB1;HSP90AB3P;HSP90AB2P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3;Putative heat shock protein HSP 90-beta 2 0 89.74700000000001 0.0067441 33267000.0 115630.0 98390.0 98384.0 136090.0 132710.0 131490.0 143080.0 135090.0 127730.0 109290.0 False True 135203.8752033991 108157.50896314293 100729.84768339786 128465.3185097332 106706.4281667063 124594.4329250843 129526.42659050539 131544.0306396866 129597.80960858046 129103.41186083597 1.0472525338767886 0.8377587191865139 0.7802260701830039 0.9950575020295312 0.8265190410438419 0.9650746725376087 1.0032765573238716 1.0189043708734935 1.0038294708142756 1.0 16.978167602190098 -6.9650634603974915 6.633897574350502 1.0049860131147408 0.8928136830071247 0.3279618578689675 0.0739254111008377 0.2135052395552074 27.722196591780556 0.02612532712653686 0.022776353977889022 1.0837685389777996e-07 6.9650634603974915 -0.11217233010761607 YESLTDPSKLDSGK ddPTM_PC-9_Lapatinib_30min_R1 2 YESLTDPSKLDSGK 14 1 P07900;P07900-2;G3V2J8;P08238;Q58FF7;Q58FF8 P07900;P08238 HSP90AA1;HSP90AB1;HSP90AB3P;HSP90AB2P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3;Putative heat shock protein HSP 90-beta 2 0 ; 120.6 0.00010928 87418000.0 679570.0 606620.0 659560.0 601920.0 685890.0 544480.0 580890.0 505830.0 650360.0 550770.0 False True 669879.2071821243 605215.408660623 605333.5227752273 646187.204746259 645547.2987116234 521193.85964487225 610965.6418834002 529332.7084232013 577109.6082055883 645969.8606451044 1.037013099207357 0.9369096695257862 0.9370925172433042 1.000336461674756 0.9993458488402864 0.8068392836848095 0.9458113746564786 0.8194387086335232 0.893400208531791 1.0 19.301107328346404 -6.736624141471578 24.999895425493108 0.8851073881089996 0.97813510332182 0.3556585185016884 0.0593176155429448 237.8475416209245 239616.8681174276 0.0185259164218575 0.01851838715819113 1.8339008784041998e-07 6.736624141471578 0.09302771521282038 YESQEPLAGQES(ph)PLPLATR ddPTM_PC-9_AZD4547_30min_R2 6 YESQEPLAGQESPLPLATR 19 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 YESQEPLAGQES(1)PLPLATR;YESQEPLAGQES(0.995)PLPLAT(0.005)R;YESQEPLAGQES(1)PLPLATR;YESQEPLAGQES(0.997)PLPLAT(0.003)R;YESQEPLAGQES(0.995)PLPLAT(0.005)R;YESQEPLAGQES(1)PLPLATR 200.4 3.2085999999999997e-15 511933800.0 205513.8 197375.9 298411.0 314359.0 315707.0 273132.0 222299.7 296513.0 241352.0 248550.0 True False 270862.91344740585 261173.7997789071 294453.8751617164 241888.3893481347 271876.53254949575 256053.01286247987 242083.9426484185 250693.72904089701 254109.37399012645 239848.34015273218 1.1293091012217304 1.088912266862448 1.2276669289193838 1.0085055797930618 1.1335351846769857 1.0675621632379393 1.0093209004250883 1.0452176941531413 1.0594585471315459 1.0 17.8717629299791 -6.629658124500238 0.8148318876228762 1.027086585662584 1.1339526037313377 0.38175599274658867 0.0529694113173785 0.6871562485457529 1.009066821698177 0.03250105741803092 0.03574717541710642 2.3460749127435375e-07 6.629658124500238 0.10686601806875373 YESQEPLAGQES(ph)PLPLATR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 YESQEPLAGQESPLPLATR 19 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 YESQEPLAGQES(1)PLPLATR;YESQEPLAGQES(1)PLPLATR;YESQEPLAGQES(1)PLPLATR;YESQEPLAGQES(1)PLPLATR;YESQEPLAGQES(1)PLPLATR;YES(0.001)QEPLAGQES(0.999)PLPLATR 297.3 2.3700999999999995e-121 476087900.0 184922.7 175235.4 200267.7 208268.1 240695.6 196813.7 200299.9 178123.7 169240.7 149761.0 True False 216226.46072018985 192631.61242158708 205042.84148748184 196599.51357129033 193533.02502782174 186492.44310128258 181326.04342630383 173448.1416126608 171715.52506555198 176911.4837925762 1.2222296488887592 1.0888587235379377 1.1590137456983225 1.1112874605799914 1.0939539982307414 1.0541567969659889 1.0249534939116987 0.9804233048885844 0.9706296130944425 1.0 17.43266817465775 -6.776706350676161 0.7144721191787753 0.9739844209724934 1.1617104899560426 0.8318391336105808 0.03144684654363514 0.2658106385745481 0.2972878683087484 0.02202362470400145 0.021891642285976304 1.6722209085828972e-07 6.776706350676161 0.18772606898354927 YESQEPLAGQES(ph)PLPLATR ddPTM_PC-9_Lapatinib_30min_R1 5 YESQEPLAGQESPLPLATR 19 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 YESQEPLAGQES(1)PLPLATR;YESQEPLAGQES(1)PLPLATR;YESQEPLAGQES(0.999)PLPLAT(0.001)R;YESQEPLAGQES(1)PLPLATR;YESQEPLAGQES(1)PLPLATR 165.41 9.4247e-08 433055000.0 222843.9 205477.3 227911.9 190437.0 217442.7 215157.1 200462.2 226658.9 227636.8 185961.5 True False 219666.10512143344 205001.5299363376 209173.86334737623 204442.3722592093 204653.1478947963 205955.33238869713 210841.1518469222 237190.299952995 201997.94646222674 218104.69749687708 1.0071589820965627 0.9399225797934633 0.9590525364561269 0.9373588675784327 0.9383252641668877 0.9442957201398475 0.9666969774914689 1.0875066088679324 0.9261512878012131 1.0 17.734661317237425 -7.542263171777907 24.99766279655184 1.0095177379538844 0.952666392652438 0.2281128543046108 0.04099451510267673 298.8556225762866 385392.0704736509 0.017898607137541083 0.01033554191409557 2.8690414865544783e-08 7.542263171777907 -0.05685134530144642 YESQNTELKT(ph)QSPEFEAQSSK ddPTM_PC-9_Lapatinib_30min_R1 1 YESQNTELKTQSPEFEAQSSK 21 1 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 YESQNT(0.002)ELKT(0.726)QS(0.272)PEFEAQSSK 75.703 0.0010197000000000001 8055200.0 48586.0 24820.0 25908.0 23138.0 23425.0 29713.0 18930.0 16859.0 31051.0 17809.0 True False 47893.154730418806 24762.530814936246 23777.944247772088 24839.645706105315 22047.187555321965 28442.244254385998 19910.10277479863 17642.33068680538 27553.709398474246 20887.26192099913 2.2929359966645095 1.1855326422675387 1.1383945075092294 1.1892246001441018 1.0555326800951683 1.3617028580367165 0.9532174609627455 0.8446454472363637 1.3191633016663118 1.0 14.350335763677856 -4.759729431588901 4.815032992932105 1.109712757028866 2.3788266438480994 0.8479991668139661 0.1497559878288814 0.06725111157318915 3.829879011841138 0.03729458438475222 0.29278287659450714 1.738883827788258e-05 4.759729431588901 1.2691138868192333 up YESQNTELKTQS(ph)PEFEAQSSK ddPTM_PC-9_AZD4547_30min_R2 1 YESQNTELKTQSPEFEAQSSK 21 1 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 YES(0.002)QNT(0.006)ELKT(0.162)QS(0.827)PEFEAQS(0.002)S(0.001)K 55.733999999999995 0.0079319 9710200.0 23994.0 16384.0 24854.0 43899.0 28398.0 29085.0 21925.0 23479.0 23565.0 32524.0 True False 31623.592893796234 21679.80759341751 24524.419720684877 33778.76378278903 24455.42788516121 27266.31035215659 23876.28252564701 19850.860043745866 24810.59779109902 31385.344659535123 1.0075910663669811 0.6907621320905587 0.7813971771450392 1.0762591314263859 0.7791989589552413 0.8687593094145889 0.7607462267709462 0.6324881966116951 0.7905153841782444 1.0 14.937803431576127 -7.26274564866684 22.97808501625174 0.7653114573278282 0.8608873092636709 0.04298000277925751 0.13538095815600235 94.5360638173492 1662881.8944039657 0.053536707996283094 0.03838525027108585 5.460775863068459e-08 7.26274564866684 0.09557585193584262 YESQNTELKTQS(ph)PEFEAQSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YESQNTELKTQSPEFEAQSSK 21 1 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 YES(0.004)QNT(0.004)ELKT(0.161)QS(0.806)PEFEAQS(0.02)S(0.004)K 61.602 0.0039296999999999995 6677800.0 16747.0 9830.5 12571.0 19350.0 21555.0 22992.0 20994.0 18933.0 18184.0 16860.0 True False 19581.93633167276 10806.40707248883 12870.740315782992 18265.88223354643 17331.4524838622 21786.25904489723 19005.29633660241 18436.028811171687 18449.90659925181 19916.584536313432 0.9831975103948916 0.5425833456929207 0.6462323041541626 0.9171192078763647 0.8702020395245066 1.0938752578372495 0.9542447552666726 0.9256621675045597 0.9263589630848873 1.0 14.281682642668242 -5.854351987823169 5.121543601539656 0.9580110095068696 0.706714715881648 0.4497390555094758 0.11732485628171122 0.1742259808767343 7.464667923210775 0.03295380604730375 0.050172209526360895 1.3984534419167974e-06 5.854351987823169 -0.25129629362522155 YESQNTELKTQS(ph)PEFEAQSSK ddPTM_PC-9_Lapatinib_30min_R1 1 YESQNTELKTQSPEFEAQSSK 21 1 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 YES(0.001)QNT(0.002)ELKT(0.036)QS(0.958)PEFEAQS(0.002)S(0.001)K 59.628 0.0052756999999999995 9983000.0 32639.0 18294.0 21573.0 17434.0 18237.0 20683.0 13584.0 16719.0 21691.0 17579.0 True False 32173.56187474047 18251.641366980002 19799.35121418818 18716.154518119107 17164.33551532153 19798.436304427876 14287.31305297753 17495.825775710255 19247.931163643847 20617.506727454867 1.5604972172458285 0.8852496865043138 0.9603174368228915 0.9077797216477265 0.8325126671337522 0.9602730614397572 0.6929699716771345 0.8485907635190587 0.9335722024047043 1.0 14.331582257870311 -4.76141895951632 10.404527867329213 0.8831803651859117 1.5627304757184795 0.8543376168850032 0.08284224714358145 0.02437051183546546 67.63370124064043 0.020594877251600807 0.11620234043019391 1.7321322209878034e-05 4.76141895951632 0.6795501105325678 YETPSDAIEVIS(ph)PASSPAPPQEK ddPTM_PC-9_Lapatinib_30min_R1 1 YETPSDAIEVISPASSPAPPQEK 23 0 O75376-2;O75376;A0A088AWL3;E7EVK1 O75376-2 NCOR1 Nuclear receptor corepressor 1 1 YETPSDAIEVIS(0.998)PAS(0.001)SPAPPQEK 143.63 6.0691e-12 0.0 9727.4 16484.0 22257.0 18574.0 21459.0 19294.0 17219.0 20168.0 22093.0 13508.0 True False 9588.68549221331 16445.83231077395 20427.11537450453 19939.99392104762 20196.823810017242 18468.840596510734 18110.515566785936 21105.07890690378 19604.653690396186 15842.839801721393 0.6052377990448062 1.0380608853336406 1.28935946018245 1.2586123555248632 1.2748234573338784 1.1657531621637691 1.1431356873796168 1.3321525162812426 1.2374456811881702 1.0 13.95154333874547 -4.8089294689626945 2.6422743506790005 1.2234684575361467 0.5013252281783804 0.8047387226779845 0.09026776989661535 0.1710187100199013 1.658016195110818 0.022468579388969668 0.27058458573055966 1.5526391438489478e-05 4.8089294689626945 -0.7221432293577663 YEVTS(ph)GGGGTSR ddPTM_PC-9_AZD4547_30min_R2 1 YEVTSGGGGTSR 12 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 YEVT(0.242)S(0.756)GGGGT(0.001)SR 71.268 0.027804000000000002 5490300.0 31317.0 33191.0 51142.0 59811.0 41580.0 44286.0 28676.0 46297.0 39577.0 39491.0 True False 41275.15456593386 43919.341664619176 50463.82366441084 46022.49802073838 35807.33472304399 41516.78941913727 31228.108447227067 39142.86244922283 41668.95942195312 38108.432110124886 1.0830976841728321 1.1524835642070514 1.324216738137681 1.207672304327389 0.9396171067749196 1.0894384030065312 0.8194540346604863 1.0271443951330421 1.0934314826057159 1.0 15.217822632320912 -6.253942883989222 24.72912470172339 0.99216465393104 1.1985079557439717 0.5225577626429879 0.0921503098222638 406.073057055776 1339535.9418496713 0.0281346631744304 0.035585640940572795 5.572590317419418e-07 6.253942883989222 0.2063433018129317 YEVTS(ph)GGGGTSR ddPTM_PC-9_Lapatinib_30min_R1 1 YEVTSGGGGTSR 12 0 P15924;P15924-2;P15924-3 P15924 DSP Desmoplakin 1 YEVT(0.008)S(0.992)GGGGTSR 103.43 0.0020978000000000004 7048500.0 51737.0 41965.0 48379.0 33319.0 35472.0 44910.0 34934.0 41509.0 37743.0 29562.0 True False 50999.2208925962 41867.83262082193 44401.46536834055 35769.390408925676 33385.60670063524 42989.30399032328 36742.711586625206 43437.65967605461 33491.98588859019 34671.75231111101 1.4709155866994594 1.2075487920293213 1.280623631881205 1.0316579931687764 0.9629050877228489 1.239894182577752 1.0597304473374 1.2528256226073249 0.9659732680386405 1.0 15.081473131771332 -4.062646103957355 0.8462167831269128 1.0898815834958488 2.365926352455728 0.5429706877952596 0.10805239279939101 5.4911856647739885 1.2705894042777184 0.03726836175583228 8.723022870449359 8.656730474162877e-05 4.062646103957355 1.2760447689598793 YEWDVAEAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YEWDVAEAR 9 0 P13639 P13639 EEF2 Elongation factor 2 0 92.439 0.020802 0.0 6676.0 6506.1 8596.6 7013.0 9536.3 6879.8 8373.4 6995.3 6710.1 3241.3 False True 7806.114942989633 7151.982610683037 8801.575546787053 6620.084346452769 7667.7304719023405 6519.011176804278 7580.21093383379 6811.680787133014 6808.222518237984 3828.9220318833172 2.0387239222915357 1.8678841071008225 2.2987084807412117 1.7289681772905083 2.00258203433065 1.7025708861451527 1.9797245466775253 1.7790074413666184 1.77810424488828 1.0 11.902722567634038 -11.497177972249169 0.2535100902523624 2.056535293165075e-12 2.0367033496875924 0.7729418435138746 0.153372735481299 13.551970784938842 0.5189614107830205 8.250459817038976 0.22148671448296522 3.182892916858486e-12 11.497177972249169 2.036703349685536 YEWDVAEAR ddPTM_PC-9_Lapatinib_30min_R1 1 YEWDVAEAR 9 0 P13639 P13639 EEF2 Elongation factor 2 0 123.21 0.0069566 7434100.0 44976.0 47401.0 50611.0 42488.0 46604.0 47468.0 41310.0 43708.0 45697.0 40216.0 False True 44334.63399241173 47291.24589680873 46449.958944109705 45612.70925581306 43862.8443469893 45437.9042933125 43448.82966861763 45738.833243898756 40550.122649257 47167.28201554837 0.9399446416648964 1.002628175208813 0.984791935409757 0.9670412902057224 0.9299421648364266 0.9633352262768545 0.9211645829898577 0.9697152621349109 0.859708698836832 1.0 15.52549884843336 -6.1041540369479685 4.206641873171791 0.9393871574329075 0.9782370004218706 0.15718653017004602 0.037492015212702935 0.38390132169549285 11.622395335665978 0.010592740271395815 0.01411967445380925 7.86766687290866e-07 6.1041540369479685 0.0388498429889631 YEYDPDIS(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 3 YEYDPDISPPR 11 0 Q9BRD0;H7C462 Q9BRD0 BUD13 BUD13 homolog 1 YEYDPDIS(1)PPR;YEYDPDIS(1)PPR;YEYDPDIS(1)PPR 150.49 9.058e-05 69302000.0 51901.0 50904.0 63265.0 77607.0 74648.0 72089.0 65648.0 91027.0 73384.0 65252.0 True False 68404.43839213628 67357.72251802513 62426.06476338331 59715.905166197575 64284.413718272976 67581.26343395632 71490.54482297266 76960.86874236782 77262.92842359479 62967.54734116301 1.0863443357816651 1.0697212351797 0.991400608716012 0.9483600312817048 1.0209134138570632 1.0732713324182035 1.1353553987998197 1.2222306885384613 1.2270277577269812 1.0 15.942320853353692 -7.1656837009090895 2.363071404040216 1.1687017855481592 1.0208763256114044 0.3998251012830565 0.06933884121952996 0.2737018716215547 2.9891549459891538 0.031799454152830066 0.022486254084716707 6.828358262244294e-08 7.1656837009090895 -0.14782545993675478 YEYDPDIS(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YEYDPDISPPR 11 0 Q9BRD0;H7C462 Q9BRD0 BUD13 BUD13 homolog 1 YEYDPDIS(1)PPR;YEYDPDIS(1)PPR;YEYDPDIS(1)PPR;YEYDPDIS(1)PPR 144.28 0.00017287 87143000.0 66380.0 77843.0 87860.0 74166.0 100779.0 67282.0 84484.0 76446.0 67033.0 55729.0 True False 77616.82293523835 85570.73859353516 89954.91561090559 70010.71946941614 81032.0783981048 63753.613476808256 76481.06390880804 74439.3735012322 68013.23081102327 65832.22654947876 1.1790095368702505 1.2998305401264405 1.3664267536705066 1.063471845613438 1.2308877072113307 0.9684255997158437 1.1617572109812468 1.13074367073525 1.0331297356303952 1.0 16.006506372347157 -5.771281361683891 24.998235877836237 1.094044209117225 1.2835631084757457 0.5305757933091584 0.08484700278312549 151.91815393823515 385866.17388643516 0.02313000438154133 0.03477979097593929 1.6932404635813787e-06 5.771281361683891 0.18951889935852062 YEYDPDIS(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 3 YEYDPDISPPR 11 0 Q9BRD0;H7C462 Q9BRD0 BUD13 BUD13 homolog 1 YEYDPDIS(1)PPR;YEYDPDIS(1)PPR;YEYDPDIS(1)PPR 155.88 0.00030349 60219000.0 43811.0 58796.0 54679.0 47221.0 53135.0 49830.0 51082.0 49336.0 60199.0 48674.0 True False 43186.24710604658 58659.8614744155 50183.50368704378 50693.789864638195 50009.70376742936 47698.88705940343 53726.776013854374 51628.330669922914 53418.754696426884 57087.23604597182 0.7564956739413535 1.027547759137914 0.8790669712338407 0.8880056800055087 0.8760225092550813 0.8355438161516869 0.9411346517212482 0.9043760785396424 0.9357390267311113 1.0 15.800880593585129 -8.599471097832664 0.9069953132002949 0.9994048084440325 0.8873957323243348 0.2353840305316688 0.06483067268807745 1.0613068812988669 1.8967101825999417 0.05930355853907563 0.02037726963124254 2.514947376419123e-09 8.599471097832664 -0.11200907611969768 YFDDEFTAQSITIT(ph)PPDR ddPTM_PC-9_AZD4547_30min_R2 2 YFDDEFTAQSITITPPDR 18 0 P31751;P31751-2;M0R0P9;M0R283 P31751 AKT2 RAC-beta serine/threonine-protein kinase 1 YFDDEFTAQSIT(0.077)IT(0.923)PPDR;YFDDEFTAQSIT(0.016)IT(0.984)PPDR 131.84 9.904799999999999e-05 5297300.0 14111.0 17343.5 13243.7 15177.3 13854.8 19192.5 16465.7 25459.0 15408.099999999999 11568.9 True False 18598.004472966535 22949.447204372344 13068.079884720142 11678.40797194751 11931.300171256133 17992.389940992452 17931.11540171248 21524.896539619505 16222.54070974041 11163.876332299105 1.6659092164214644 2.0556880532593738 1.1705683129892646 1.0460889770123816 1.0687417001151054 1.6116615237789071 1.6061728800985131 1.9280844662659065 1.453127948292089 1.0 13.446550427718254 YFDDEFTAQSITIT(ph)PPDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YFDDEFTAQSITITPPDR 18 0 P31751;P31751-2;M0R0P9;M0R283 P31751 AKT2 RAC-beta serine/threonine-protein kinase 1 YFDDEFTAQSIT(0.003)IT(0.997)PPDR;YFDDEFTAQSIT(0.124)IT(0.876)PPDR 130.77 0.0001006 3832600.0 6961.6 13921.5 9628.5 5730.7 10211.5 5492.9 8204.9 5273.5 4339.6 6106.1 True False 8140.061382132509 15303.534516011727 9858.079956289599 5409.627458180077 8210.629878866097 5204.842654302196 7427.672473668145 5135.0762127351145 4403.058440283386 7213.087594138997 1.1285127590501918 2.1216343647963782 1.366693503666834 0.7499739033497494 1.1382961556626117 0.7215831759108814 1.0297493794063322 0.7119109737288685 0.6104263095128771 1.0 12.816401228350315 -5.609671969245223 4.443905603591258 0.8559059493124191 1.6525098041223616 0.5802061096925546 0.2726134659238893 0.12845652642302777 4.595838474878324 0.07083215098710009 0.12809105067997023 2.456563703685782e-06 5.609671969245223 0.7966038548099424 YFDDEFTAQSITIT(ph)PPDR ddPTM_PC-9_Lapatinib_30min_R1 4 YFDDEFTAQSITITPPDR 18 0 P31751;P31751-2;M0R0P9;M0R283 P31751 AKT2 RAC-beta serine/threonine-protein kinase 1 YFDDEFTAQSIT(0.004)IT(0.996)PPDR;YFDDEFTAQSIT(0.008)IT(0.992)PPDR;YFDDEFT(0.001)AQS(0.012)IT(0.009)IT(0.978)PPDR;YFDDEFTAQS(0.004)IT(0.021)IT(0.974)PPDR 195.45 4.1708e-14 6603400.0 26402.5 48628.7 41794.0 36931.100000000006 49462.6 46152.1 48485.6 50264.6 54278.7 42737.5 True False 26025.9955083745 48516.10323288843 38357.85864950544 39647.13629253807 46553.30711521316 44178.28226879978 50995.94712613718 52600.07681594387 48165.26122594971 50124.61993086085 0.5192257925201893 0.9679096479895286 0.7652498652840494 0.7909713100513311 0.9287513237891127 0.8813689226918205 1.0173832179970281 1.0493860479839554 0.9609102531328164 1.0 15.613231771946113 -3.6229934786112694 0.31040118795239624 1.027516635162467 5.088891630155033e-11 0.5917751254054182 0.09673161152866747 11.566881325085888 0.5147607096337194 0.09917179707359237 5.138021281178893 0.00023823552426614444 3.6229934786112694 -1.027516635111578 YFDEHYEYR ddPTM_PC-9_AZD4547_30min_R2 1 YFDEHYEYR 9 0 P33552 P33552 CKS2 Cyclin-dependent kinases regulatory subunit 2 0 132.01 0.0010199999999999999 6097800.0 31585.0 38262.0 41982.0 43247.0 43148.0 43136.0 45506.0 58245.0 40680.0 42729.0 False True 41628.37299118756 50629.44324580937 41425.29124944852 33277.07230948944 37157.64498869415 40438.69910093269 49555.94584319694 49244.57358694915 42830.261750133985 41233.070715695416 1.009587020045579 1.227884374532824 1.0046618049642355 0.8070481225843431 0.9011612364477635 0.9807345996556994 1.2018495101877875 1.1942979926596673 1.0387356800431211 1.0 15.331514285387163 -7.240691777156754 23.51318318906518 1.1249122927344648 0.987908476388932 0.2025620943063463 0.11506054498025257 606.4764174424054 687317.790933194 0.04862824602634325 0.03761370801469925 5.74524062635524e-08 7.240691777156754 -0.13700381634553283 YFDEHYEYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YFDEHYEYR 9 0 P33552 P33552 CKS2 Cyclin-dependent kinases regulatory subunit 2 0 ; 160.82 0.00012215 8422800.0 48458.0 71638.0 79452.0 55189.0 65560.0 44398.0 57719.0 51480.0 51766.0 37273.0 False True 56660.982310873536 78749.74720095175 81346.43700338813 52096.939255152094 52713.9886263978 42069.6907217879 52251.438470627494 50128.704547568734 52522.97981834957 44030.29984709433 1.2868634214993369 1.7885353375840944 1.8475104027427238 1.183206551762561 1.1972207504709176 0.9554713655797232 1.1867154812046028 1.1385047279181055 1.1928826285705092 1.0 15.42620904863559 -5.840534046709485 6.65218177364258 1.1227300361248593 1.6539776432411812 0.693856330061695 0.15814413783287465 0.11295292533346524 7.664807518021111 0.04455403152881243 0.06684310970967448 1.4436634232168127e-06 5.840534046709485 0.5312476071163219 YFDEHYEYR ddPTM_PC-9_Lapatinib_30min_R1 2 YFDEHYEYR 9 0 P33552 P33552 CKS2 Cyclin-dependent kinases regulatory subunit 2 0 ; 140.83 0.00063127 11722200.0 57687.0 97006.0 85737.0 76920.0 103373.0 85196.0 89392.0 98035.0 109093.0 78414.0 False True 56864.3728014998 96781.3885670308 78688.03481439072 82576.95339759788 97292.8033791376 81552.36568157609 94020.28036158482 102590.06399436285 96805.79753978146 91967.75541991282 0.6183077160235613 1.0523404439429835 0.8556046024512762 0.8978902770929034 1.057901249572867 0.8867495494395681 1.0223178757848383 1.1155003569017201 1.052605851885574 1.0 16.488840509742957 -4.755481305449049 24.99885765664435 0.9893342114045984 0.6183071123861961 0.6552194905139306 0.0815863667259489 130.79094199277537 548717.8178651807 0.02153896015525244 0.1906360357896251 1.7559764799747315e-05 4.755481305449049 -0.37102709901840236 YFDPANGK ddPTM_PC-9_Lapatinib_30min_R1 2 YFDPANGK 8 0 P13639 P13639 EEF2 Elongation factor 2 0 ; 106.36 0.017634 21360900.0 131909.0 139705.0 132974.0 116751.0 141197.0 118934.0 148082.0 122108.0 111982.0 115392.0 False True 130027.95347085175 139381.52165594982 122041.39101448402 125337.2580099186 132892.07006398268 113847.47006869524 155748.9613892091 127781.58345717026 99369.40793726261 135337.3534498248 0.9607691458150062 1.0298821286439916 0.9017568904931325 0.9261098640914858 0.981931940269922 0.8412124750976696 1.1508202090485813 0.9441708456678535 0.7342348982323125 1.0 17.046200556170334 -8.021369102187696 24.718449084479904 0.8578125611062446 0.969761865058609 0.14709182138967325 0.09755479265831238 1133.0339311417245 1310614.5772138974 0.06145485803955465 0.02375166872833061 9.51986736869056e-09 8.021369102187696 0.11194930395236435 YFDS(ph)GDYNMAK ddPTM_PC-9_AZD4547_30min_R2 6 YFDSGDYNMAK 11 0 A6NMQ3;Q5T5H1;O43768-2;O43768;O43768-9;O43768-3;O43768-4;O43768-6;O43768-5;O43768-7;P56211;H3BQ52;H3BMD8;P56211-2;H3BTD3 A6NMQ3;P56211;P56211-2 ENSA;ARPP19 Alpha-endosulfine;cAMP-regulated phosphoprotein 19 1 Y(0.004)FDS(0.982)GDY(0.014)NMAK;Y(0.002)FDS(0.917)GDY(0.081)NMAK;YFDS(0.971)GDY(0.029)NMAK;YFDS(0.913)GDY(0.087)NMAK;Y(0.002)FDS(0.998)GDYNMAK;Y(0.363)FDS(0.636)GDY(0.001)NMAK 107.65 0.0022837 203834400.0 431771.0 415248.0 731702.0 752834.0 553653.0 541258.0 597523.0 545472.0 422271.0 485362.0 True False 569065.1966052878 549468.7953827782 721999.1533944069 579279.7524693549 476787.8376964274 507413.0516963243 650701.389444568 461181.83609958465 444591.3829766673 468369.62411269505 1.2149916803066723 1.1731520728393132 1.5415157521417011 1.2368004299313262 1.0179734405271912 1.0833602897660053 1.3892903295709924 0.9846535991168783 0.9492318888504468 1.0 18.837287988015028 -7.430334903647782 0.5458500641889708 0.9615199442143595 1.2879288541024243 0.3226061571035356 0.15042275660838592 1.1255003190308033 0.7080864331602575 0.15429376042896975 0.11388581302845355 3.71248832320652e-08 7.430334903647782 0.3264089098880648 YFDS(ph)GDYNMAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 YFDSGDYNMAK 11 0 A6NMQ3;Q5T5H1;O43768-2;O43768;O43768-9;O43768-3;O43768-4;O43768-6;O43768-5;O43768-7;P56211;H3BQ52;H3BMD8;P56211-2;H3BTD3 A6NMQ3;P56211;P56211-2 ENSA;ARPP19 Alpha-endosulfine;cAMP-regulated phosphoprotein 19 1 YFDS(0.977)GDY(0.022)NMAK;YFDS(1)GDYNMAK;YFDS(0.999)GDY(0.001)NMAK 97.95700000000001 0.0045573 125957000.0 328106.0 371670.0 334926.0 438405.0 400496.0 396758.0 480912.0 344758.0 372827.0 264906.0 True False 383647.86541110824 408566.9413185409 342911.90605392883 413842.5891781866 322021.68378459144 375951.3120274586 435356.5338586331 335708.46780129615 378278.88955561287 312931.3608052574 1.225980880995366 1.3056120047130693 1.0958054992363928 1.3224708067393987 1.02904893570252 1.2013858600174612 1.3912205307206744 1.0727862715242955 1.2088238410563854 1.0 18.255486721737448 -9.13229569238818 0.9447052175399462 0.9994237368510993 1.211900988489242 0.2441667501516851 0.10913494908559344 3.4564527932796936 4.130414860428817 0.10864644582981861 0.03337048159000041 7.374019939483302e-10 9.13229569238818 0.21247725163814268 YFDS(ph)GDYNMAK ddPTM_PC-9_Lapatinib_30min_R1 11 YFDSGDYNMAK 11 0 A6NMQ3;Q5T5H1;O43768-2;O43768;O43768-9;O43768-3;O43768-4;O43768-6;O43768-5;O43768-7;P56211;H3BQ52;H3BMD8;P56211-2;H3BTD3 A6NMQ3;P56211;P56211-2 ENSA;ARPP19 Alpha-endosulfine;cAMP-regulated phosphoprotein 19 1 YFDS(0.995)GDY(0.005)NMAK;YFDS(0.997)GDY(0.003)NMAK;YFDS(0.998)GDY(0.002)NMAK;YFDS(0.894)GDY(0.106)NMAK;YFDS(0.998)GDY(0.002)NMAK;Y(0.001)FDS(0.998)GDY(0.001)NMAK;Y(0.005)FDS(0.985)GDY(0.01)NMAK;YFDS(1)GDYNMAK;Y(0.06)FDS(0.931)GDY(0.009)NMAK;Y(0.206)FDS(0.794)GDYNMAK;Y(0.062)FDS(0.938)GDYNMAK 141.58 0.00013251 750759900.0 996024.0 1023872.0 840623.0 659428.0 655146.0 822245.0 719957.0 798527.0 554537.0 464248.0 True False 981820.5151115697 1021501.2872905099 771510.22183862 707924.5349073221 616611.6003465945 787079.4980967116 757232.8506833444 835629.4795861325 492079.2035265118 544492.6482284237 1.8031841537365987 1.8760607523611104 1.4169341392373744 1.3001544414064083 1.132451654494912 1.4455282374474205 1.390712717879843 1.5346937783365113 0.9037389304108224 1.0 19.054553044157693 -1.522878745282486 0.35613384156432404 1.1882369119078608 10.176022978983232 0.5751518063593437 0.1948602330958914 49.02351157318303 0.6866642740907838 0.1665777721665842 297.598064392641 0.029999999999851597 1.522878745282486 8.98778606707537 YFDSGDY(ph)NMAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YFDSGDYNMAK 11 0 A6NMQ3;Q5T5H1;O43768-2;O43768;O43768-9;O43768-3;O43768-4;O43768-6;O43768-5;O43768-7;P56211;H3BQ52;H3BMD8;P56211-2;H3BTD3 A6NMQ3;P56211;P56211-2 ENSA;ARPP19 Alpha-endosulfine;cAMP-regulated phosphoprotein 19 1 YFDSGDY(1)NMAK;Y(0.001)FDS(0.178)GDY(0.822)NMAK 72.547 0.028261 119303000.0 237979.0 258227.0 211066.0 310581.0 280915.0 251291.0 320161.0 252380.0 246010.0 181709.0 True False 278264.1444004992 283862.0699972097 216098.6139122626 293180.15348718833 225871.72231520046 238112.85758747684 289833.03231508774 245755.29241871394 249607.43084480538 214651.40329234718 1.2963537164558567 1.3224328639053908 1.0067421437629476 1.3658431717210249 1.0522722835758573 1.1093002604934106 1.3502498836233834 1.1449041965218574 1.1628502167528316 1.0 17.711636078931342 -14.522878745280284 0.14565658233742682 0.31825569841814805 1.2633847927658421 0.22516668890135705 0.11894499245467582 221.91480319256266 1.9392693241367205 44.04752777184317 0.6475681350400192 3.0000000000003694e-15 14.522878745280284 0.9451290943476941 YFEADPPGQVAAS(ph)PDPTT ddPTM_PC-9_AZD4547_30min_R2 2 YFEADPPGQVAASPDPTT 18 0 H0Y8X4;O43598 H0Y8X4 DNPH1 2-deoxynucleoside 5-phosphate N-hydrolase 1 1 YFEADPPGQVAAS(0.972)PDPT(0.014)T(0.014);YFEADPPGQVAAS(0.983)PDPT(0.012)T(0.004) 113.33 0.00015766 5049500.0 20193.3 22748.5 27962.6 37010.1 33782.4 32622.8 26903.6 36688.8 25942.2 33777.8 True False 26614.349353267313 30101.507753836548 27591.797653561727 28477.993245344987 29092.296886670538 30582.891158890638 29297.96828082084 31019.388984751633 27313.45172994904 32595.249503162155 0.8165100669251015 0.9234937057596788 0.8464975134147991 0.873685389111142 0.8925318054045948 0.9382622199570434 0.8988416633527706 0.9516536752308755 0.8379580505220335 1.0 14.992374098066287 -6.477759963080519 3.055921056501846 0.9206282004299778 0.8679720951014913 0.2717140581585138 0.04601511653277618 0.3913911032853763 7.308555230775623 0.014540679372647634 0.01593882083157242 3.328434668566354e-07 6.477759963080519 -0.052656105328486524 YFEADPPGQVAAS(ph)PDPTT ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 YFEADPPGQVAASPDPTT 18 0 H0Y8X4;O43598 H0Y8X4 DNPH1 2-deoxynucleoside 5-phosphate N-hydrolase 1 1 YFEADPPGQVAAS(0.879)PDPT(0.061)T(0.061);YFEADPPGQVAAS(0.963)PDPT(0.019)T(0.019);YFEADPPGQVAAS(0.999)PDPTT 99.569 0.005441 1324700.0 36318.2 34745.9 39568.0 41263.1 45969.5 38585.2 43606.3 39083.4 37050.6 32794.5 True False 42466.1539428529 38195.24332434665 40511.45118247562 38951.262283775184 36962.10646981686 36561.724186637475 39475.59558172741 38057.50216228532 37592.394932151255 38739.88324888086 1.09618693660053 0.9859411056807987 1.0457298211823065 1.0054563673704522 0.9541099087046072 0.9437747644139761 1.0189910828620734 0.9823855667759335 0.9703796650764879 1.0 15.241531985619826 -1.522879032562309 0.7140462666712757 0.9814516336119282 15.17982089651599 0.5377300306035226 0.029152890012903613 255.02929667592088 1.2787603448363352 0.011633921462697186 5794.403806551839 0.02999998015527102 1.522879032562309 14.19836926290406 YFEADPPGQVAAS(ph)PDPTT ddPTM_PC-9_Lapatinib_30min_R1 2 YFEADPPGQVAASPDPTT 18 0 H0Y8X4;O43598 H0Y8X4 DNPH1 2-deoxynucleoside 5-phosphate N-hydrolase 1 1 YFEADPPGQVAAS(0.99)PDPT(0.006)T(0.004);YFEADPPGQVAAS(0.905)PDPT(0.048)T(0.048) 98.572 0.00070266 5267500.0 55819.0 51992.0 58783.0 47767.0 62267.0 54436.0 54868.0 57624.0 62156.0 44308.0 True False 55023.01082404905 51871.615718378984 53950.08864894192 51279.94452604079 58604.577481632135 52107.89917651384 57708.79656881412 60301.42140675445 55155.33674830334 51966.57876330112 1.0588153411959147 0.9981726131066916 1.038168952677746 0.9867870032316763 1.1277359194371053 1.0027194480871333 1.1104982845160505 1.1603885197333679 1.061361707098835 1.0 15.665296461382075 -6.255141256176918 24.994016744213926 1.0830858946028876 1.0201552362928796 0.22368068121297247 0.05096126658067416 709.282017389683 2814772.5753979264 0.014970258247180457 0.018799237777446208 5.557234763844254e-07 6.255141256176918 -0.06293065831000799 YFEADPPGQVAASPDPT(ph)T ddPTM_PC-9_AZD4547_30min_R2 1 YFEADPPGQVAASPDPTT 18 0 H0Y8X4;O43598 H0Y8X4 DNPH1 2-deoxynucleoside 5-phosphate N-hydrolase 1 1 YFEADPPGQVAAS(0.004)PDPT(0.498)T(0.498) 138.66 0.00030161 2624900.0 40540.0 47586.0 53523.0 66655.0 64664.0 61741.0 48838.0 59611.0 46482.0 53041.0 True False 53430.87671561641 62967.24390505164 52813.25004869304 51288.719559484365 55686.51978188833 57880.32550979887 53184.48738825767 50399.489674506396 48938.94362511625 51184.0507344239 1.0438969942580454 1.2302122048090058 1.0318302145080795 1.0020449500099855 1.0879662508703378 1.1308273706221414 1.0390832031683723 0.9846717669144961 0.9561365879196094 1.0 15.643406707138054 -7.606915803847274 3.257249152609746 0.9770811892019636 1.0878935180344822 0.39251746164057066 0.0597717076258017 0.26652003531026175 5.645788191410142 0.03294669700451259 0.01760628152518566 2.4722033816782865e-08 7.606915803847274 0.11081232883251857 YFGGTEDR ddPTM_PC-9_AZD4547_30min_R2 2 YFGGTEDR 8 0 Q16658 Q16658 FSCN1 Fascin 0 ; 107.43 0.017555 67653000.0 195115.0 167348.0 238150.0 363880.0 302980.0 229692.0 173526.0 286230.0 219860.0 264930.0 False True 257157.51135588283 221439.96833149594 234991.97539555418 279993.0878899579 260916.45681548544 215329.32292960494 188969.47783559508 241999.73041106501 231481.3507469142 255654.881338416 1.005877572176992 0.8661675739270199 0.9191765639885833 1.0951994596157344 1.0205807745564013 0.8422656426597573 0.7391584969795747 0.9465875603240473 0.9054446742227356 1.0 17.96383804677692 -6.765086929317902 24.999691603774295 0.874132192666607 0.9778638596274266 0.226665220704253 0.08579263008900806 144.39615149588414 989659.665350211 0.03140673769313439 0.028777047036104952 1.717564561330264e-07 6.765086929317902 0.10373166696081959 YFGGTEDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YFGGTEDR 8 0 Q16658 Q16658 FSCN1 Fascin 0 94.006 0.031633999999999995 8305100.0 34570.0 46806.0 44909.0 51463.0 52238.0 42324.0 37138.0 34771.0 43875.0 26327.0 False True 40422.01821137682 51452.59034992239 45979.80087833091 48579.69495529716 42002.33889362065 40104.45493285625 33620.01978416404 33858.29809291982 44516.58887165491 31099.876695582683 1.2997485040549444 1.6544306864480443 1.4784560507553948 1.5620542624915694 1.3505628753694225 1.289537425675792 1.0810338611065717 1.0886955734370782 1.4314072466395948 1.0 14.924621239936709 -6.701244034824014 1.9179348433845096 1.1613916760014322 1.5071953369238973 0.5554920602947826 0.13713969420961564 0.24365650936248465 1.8458048833856129 0.052649984365531394 0.050366316841543086 1.9895550720568653e-07 6.701244034824014 0.34580366092246506 YFGGTEDR ddPTM_PC-9_Lapatinib_30min_R1 2 YFGGTEDR 8 0 Q16658 Q16658 FSCN1 Fascin 0 ; 97.602 0.026552 64631000.0 243960.0 190405.0 269470.0 239520.0 248070.0 231045.0 219360.0 207651.0 259840.0 165198.0 False True 240481.085663215 189964.1289209483 247315.21678428055 257135.0998152975 233479.01032438478 221163.74394220082 230717.387463277 217299.22352724551 230574.08296349747 193752.25418750115 1.24117825968875 0.9804486131919429 1.276450784128398 1.3271334617168296 1.205038936468004 1.1414770107818852 1.1907855649514318 1.1215313310210941 1.190045937428746 1.0 17.563853569784776 -9.664923397674377 0.5234172694891885 0.9800308875488654 1.19480582698496 0.2882836686828546 0.08891266075072277 7.502015447464036 2.2581712756647794 0.40378101698191243 0.04398827295130109 2.1631000249594807e-10 9.664923397674377 0.2147749394360946 YFLQGMGYMAS(ph)SCMTR ddPTM_PC-9_AZD4547_30min_R2 1 YFLQGMGYMASSCMTR 16 0 Q9UN36-6;Q9UN36-2;Q9UN36-5;Q9UN36-4;A0A0A0MS87;H0YJT9;G3V578;Q9UN36-3;Q9UN36 Q9UN36-6;Q9UN36-3 NDRG2 Protein NDRG2 1 Y(0.001)FLQGMGY(0.032)MAS(0.736)S(0.192)CMT(0.04)R 54.763999999999996 0.034722 4675100.0 14036.0 17002.0 20881.0 21504.0 16634.0 18890.0 15379.0 22315.0 14906.0 17602.0 True False 18499.156033063446 22497.56400776882 20604.104296596975 16546.585033488114 14324.65622374012 17708.80531381256 16747.701206929316 18866.729497686847 15693.90072879787 16985.75933763183 1.0890979711503799 1.324495629578692 1.213022266890873 0.9741445586615178 0.8433332851952015 1.0425677746757445 0.9859848402434916 1.1107380672636602 0.9239446065874808 1.0 14.052038093977854 -5.758246943214573 20.33699249752298 0.9843649927892018 1.2204351496079042 0.5992990026353775 0.08448834717902687 5.1279913118768 32657.205646935497 0.023208357258498746 0.03795338891779713 1.7448297470601601e-06 5.758246943214573 0.23607015681870247 YFPSSLS(ph)PVTPSESLPR ddPTM_PC-9_AZD4547_30min_R2 1 YFPSSLSPVTPSESLPR 17 0 K7EQ21;Q9P0U4;Q9P0U4-2;K7EKZ6 K7EQ21 CXXC1 CXXC-type zinc finger protein 1 1 YFPS(0.074)S(0.074)LS(0.824)PVT(0.023)PS(0.004)ES(0.001)LPR 91.789 0.0021564 3248000.0 17571.0 16310.0 17759.0 23994.0 21172.0 22998.0 18981.0 22529.0 15880.0 20492.0 True False 23158.212500495705 21581.888540566386 17523.504056475544 18462.554003604622 18232.63325532198 21559.931424407678 20670.272228930728 19047.660714917612 16719.384380337473 19774.581317279375 1.1711101301679472 1.0913954735268026 0.8861630886295023 0.9336508170451994 0.9220237315158721 1.0902851028035792 1.045295063257227 0.9632396463571865 0.8454987800792415 1.0 14.27135952871633 -5.054972026735726 4.766175038085297 0.9650897826387581 1.1563351592081061 0.5103223035987761 0.06864687573475037 0.16131367136523472 7.7362073658763695 0.018967441830999406 0.05906567866677262 8.811056239172144e-06 5.054972026735726 0.19124537656934804 YFPSSLS(ph)PVTPSESLPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YFPSSLSPVTPSESLPR 17 0 K7EQ21;Q9P0U4;Q9P0U4-2;K7EKZ6 K7EQ21 CXXC1 CXXC-type zinc finger protein 1 1 YFPS(0.093)S(0.07)LS(0.833)PVT(0.005)PSESLPR;YFPS(0.012)S(0.012)LS(0.958)PVT(0.013)PS(0.004)ES(0.001)LPR 86.777 0.018116 0.0 29217.0 33412.0 30101.0 32324.0 43501.0 28718.0 29923.0 31501.0 28330.0 22608.0 True False 34162.8610379461 36728.92254778461 30818.721998678215 30512.991075821945 34977.29132454139 27211.97752485033 27088.476816240527 30674.132128068413 28744.272654905617 26706.651435170483 1.2791892357181252 1.3752724723630314 1.1539717764126907 1.1425240318836387 1.3096846457687745 1.0189213571348137 1.0142970144346592 1.1485577741758026 1.076296394727036 1.0 14.704911477172738 -4.490236156177042 0.2811345208351739 1.0141925185202452 1.6502999521982116 0.5672975464466146 0.08229211253456128 7.687869918312174 0.4433130170203125 0.10384648303528883 1.7385356579112206 3.234177443384854e-05 4.490236156177042 0.6361074336779664 YFPSSLS(ph)PVTPSESLPR ddPTM_PC-9_Lapatinib_30min_R1 2 YFPSSLSPVTPSESLPR 17 0 K7EQ21;Q9P0U4;Q9P0U4-2;K7EKZ6 K7EQ21 CXXC1 CXXC-type zinc finger protein 1 1 YFPS(0.001)S(0.006)LS(0.925)PVT(0.066)PS(0.002)ES(0.001)LPR;YFPSS(0.005)LS(0.954)PVT(0.027)PS(0.009)ES(0.004)LPR 105.39 0.00072538 2051400.0 22370.3 23256.0 30699.0 27041.0 32154.0 31351.0 28960.0 29246.0 31473.0 28436.0 True False 22051.29541978942 23202.15216084437 28175.046721566923 29029.685346131617 30262.76493719627 30010.190812750494 30459.407097631713 30604.8759277721 27928.179314617246 33351.12471141172 0.6611859603116819 0.6956932445791044 0.8448004966958819 0.8704259780540042 0.907398631952022 0.8998254503387688 0.91329474976325 0.9176564866281723 0.8373984252789258 1.0 15.025447794279124 -5.283075310348869 1.5117758971288557 0.9067127375235124 0.6384832163001252 0.8487928576116875 0.03823794500671829 0.1793435392749823 0.6732735605187271 0.010765268064665557 0.05383736240638362 5.211043393548168e-06 5.283075310348869 -0.2682295212233873 YFPSSLS(ph)PVTPSESLPRPR ddPTM_PC-9_AZD4547_30min_R2 1 YFPSSLSPVTPSESLPRPR 19 1 K7EQ21;Q9P0U4;Q9P0U4-2;K7EKZ6 K7EQ21 CXXC1 CXXC-type zinc finger protein 1 1 YFPS(0.016)S(0.086)LS(0.898)PVTPSESLPRPR 71.89399999999999 0.0028259 13164000.0 44801.0 37480.0 44736.0 64521.0 47652.0 45137.0 43716.0 50828.0 48103.0 45052.0 True False 59046.78608131055 49594.67703865287 44142.771410016845 49646.680289513 41036.34233339329 42314.576254608626 47606.63931088643 42973.70051124472 50645.62637577918 43474.74319276154 1.358185966033302 1.1407698676621576 1.0153658921984507 1.1419660392100734 0.9439122423666383 0.973314001349959 1.0950413001821444 0.988475085883883 1.164943658234457 1.0 15.407889885042815 -4.728804438592327 1.9282766253180754 1.0384044376559352 1.4876966219837007 0.6594545856984217 0.06933592594550757 0.544822233720165 1.9424895765090304 0.018185530720875618 0.4627833256043885 1.8672203048522678e-05 4.728804438592327 0.4492921843277655 YFPSSLS(ph)PVTPSESLPRPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YFPSSLSPVTPSESLPRPR 19 1 K7EQ21;Q9P0U4;Q9P0U4-2;K7EKZ6 K7EQ21 CXXC1 CXXC-type zinc finger protein 1 1 YFPS(0.074)S(0.206)LS(0.717)PVT(0.002)PSESLPRPR;YFPS(0.007)S(0.018)LS(0.975)PVTPSESLPRPR 89.917 0.00048515 24066000.0 19237.6 20861.0 25485.0 23140.0 30456.0 27981.0 22521.0 24135.0 25441.0 19531.9 True False 22494.145720080505 22931.942214453935 26092.659052400722 21843.54082089222 24488.365430225324 26513.627102264694 20387.647842079765 23501.4818231463 25813.02649535664 23072.878855564664 0.974917168373006 0.9938916750704154 1.1308800785432873 0.9467193477516155 1.0613485028687382 1.1491252248251718 0.8836195937969274 1.018576050707182 1.1187605437945214 1.0 14.493910403142378 -5.019568867767052 24.613839799895914 1.0370416155441682 0.9796607250864943 0.07236173520641087 0.07878400163147115 1531.288865309682 1926081.3530594278 0.019814466743284454 0.05423955847962934 9.559410956984948e-06 5.019568867767052 -0.057380890457673916 YFPSSLS(ph)PVTPSESLPRPR ddPTM_PC-9_Lapatinib_30min_R1 2 YFPSSLSPVTPSESLPRPR 19 1 K7EQ21;Q9P0U4;Q9P0U4-2;K7EKZ6 K7EQ21 CXXC1 CXXC-type zinc finger protein 1 1 Y(0.001)FPS(0.113)S(0.241)LS(0.645)PVTPSESLPRPR;YFPS(0.037)S(0.12)LS(0.842)PVT(0.001)PSESLPRPR 75.703 0.0018660999999999999 19925200.0 64419.0 71468.0 69766.0 50822.0 61192.0 60241.0 56316.0 58403.0 57046.0 50082.0 True False 63500.373247002215 71302.52023698087 64030.10878454796 54559.61941722206 57592.806868100844 57664.63285862977 59231.76692369571 61116.616590633734 50620.87875898885 58738.60696992975 1.081067061728416 1.2138953222619495 1.090085585743072 0.9288545001612473 0.9804932367154113 0.9817160438985251 1.0083958401331925 1.0404846104355414 0.8617991023332128 1.0 15.842021431024182 -5.591438231790936 4.964131134415558 0.976312169274934 1.1490009863300354 0.6390681719880984 0.05490937441143828 0.1140720872774223 5.3352367269547685 0.014428298066849147 0.02589357782318893 2.561897608054875e-06 5.591438231790936 0.17268881705510142 YFPSSLSPVT(ph)PSESLPRPR ddPTM_PC-9_AZD4547_30min_R2 1 YFPSSLSPVTPSESLPRPR 19 1 K7EQ21;Q9P0U4;Q9P0U4-2;K7EKZ6 K7EQ21 CXXC1 CXXC-type zinc finger protein 1 1 YFPSSLS(0.149)PVT(0.849)PS(0.002)ESLPRPR 129.74 0.00038212 4102200.0 11402.0 9672.4 14455.0 17089.0 17334.0 16310.0 11894.0 13706.0 9167.7 15540.0 True False 15027.59882366695 12798.814145908904 14263.317255270782 13149.395072418087 14927.473306619631 15290.13312166664 12952.542958268896 11588.052632547422 9652.285905769506 14995.949330007874 1.0021105361829772 0.8534847553997559 0.9511446685625266 0.8768631303724992 0.9954336986687987 1.0196175503920972 0.8637361112143805 0.7727455179752423 0.6436595438779359 1.0 13.872285235556838 -7.543008139987652 4.349083951302287 0.7840222162208748 0.9445091305942864 0.31116574177379885 0.09547485397705978 0.21901462380652897 9.958383386951702 0.04448203869865898 0.025821259761661903 2.864124287081239e-08 7.543008139987652 0.16048691437341167 YFQINQDEEEEEDED ddPTM_PC-9_AZD4547_30min_R2 3 YFQINQDEEEEEDED 15 0 K7ERI7;P35268 K7ERI7 RPL22 60S ribosomal protein L22 0 ;; 142.19 8.244200000000001e-05 16784400.0 133844.0 128550.0 163813.0 225026.0 184012.0 166786.0 139488.0 170902.0 152425.0 150960.0 False True 176403.6078718536 170101.27356773795 161640.7325864873 173149.73231704306 158465.11007832515 156356.84505397276 151902.16177593812 144493.02283726967 160481.87431819513 145674.9363486481 1.2109400030878452 1.167677006294546 1.1095987864352164 1.1886034527081497 1.0877994118292658 1.0733270181753114 1.042747404484092 0.9918866378733145 1.1016436893036228 1.0 17.152393154749575 -6.5403569005310604 0.9815584278580094 1.0291532080025274 1.176292986719609 0.7185168748883759 0.03773753234032044 0.2900847526769645 0.6046072871751279 0.01936110603525556 0.02231200753442221 2.881662397387341e-07 6.5403569005310604 0.14713977871708162 YFQINQDEEEEEDED ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 YFQINQDEEEEEDED 15 0 K7ERI7;P35268 K7ERI7 RPL22 60S ribosomal protein L22 0 ;;;; 181.53 6.129699999999999e-05 46869100.0 208203.0 221410.0 230203.0 237527.0 270506.0 227572.0 245942.0 256025.0 232536.0 180443.0 False True 243447.65570330655 243390.12155228638 235691.91256973866 224219.13226292364 217502.2911435692 215637.72370239036 222644.59329411533 249304.6150309104 235936.39908510912 213155.88751399756 1.1421108679783465 1.1418409521355746 1.1057255575652876 1.0519021307736554 1.020390727557484 1.011643291758619 1.0445153351886407 1.169588219863451 1.1068725421417958 1.0 17.701549378530324 -5.537153932892625 3.1353747582302267 1.0610039863354874 1.1409337119000185 0.34443076702036846 0.04704724172339931 0.3274638893318298 6.5963466157556185 0.014690043470910706 0.030672482288764836 2.9029935246621335e-06 5.537153932892625 0.07992972556453104 YFQINQDEEEEEDED ddPTM_PC-9_Lapatinib_30min_R1 4 YFQINQDEEEEEDED 15 0 K7ERI7;P35268 K7ERI7 RPL22 60S ribosomal protein L22 0 ;;; 155.26 0.0001119 45870900.0 309288.0 282480.0 332481.0 273789.0 286839.0 292642.0 265073.0 263817.0 287203.0 231275.0 False True 304877.4964035278 281825.9349155191 305145.69559377444 293924.3563933293 269967.6939671715 280126.3838418209 278797.1829278496 276074.9009313085 254855.17375833305 271250.57559543295 1.12396995189514 1.038987417065832 1.124958702572103 1.0835897979133287 0.9952704925125214 1.03272180428338 1.0278215348146296 1.0177854934511585 0.9395562505218296 1.0 18.049266673405157 -6.503391234453852 0.6449028400480616 0.9850465844340651 1.1038972449223894 0.6101146054396434 0.03450155261016338 0.5998245078889971 0.5507651035874194 0.02532657743174034 0.03599909437216459 3.137680838596961e-07 6.503391234453852 0.11885066048832427 YFQS(ph)PSR ddPTM_PC-9_AZD4547_30min_R2 1 YFQSPSR 7 0 Q16629-4;Q16629;H7BZZ6 Q16629-4 SRSF7 Serine/arginine-rich splicing factor 7 1 YFQS(0.5)PS(0.5)R 99.01299999999999 0.011978 4435300.0 27253.0 19185.0 27787.0 34587.0 28320.0 35963.0 24560.0 34157.0 30448.0 26048.0 True False 35918.887102385124 25386.176066877124 27418.52622429673 26613.501513823172 24388.25683878322 33714.22792486188 26745.79242097564 28878.82049977545 32057.419119176015 25136.067448394155 1.4289779885468856 1.0099501888669122 1.090804131576612 1.0587774546858724 0.9702494986080765 1.3412689950040595 1.0640404460994681 1.1488997059331334 1.2753553906151711 1.0 14.617471336528013 -6.7369049178846225 24.999553502698202 1.1688523820198133 1.101989533715618 0.030620901466453132 0.1468692501897939 842.0118507485473 857971.8623272815 0.047017348599953185 0.046996749054831054 1.8327156234258015e-07 6.7369049178846225 -0.06686284830419531 YFQS(ph)PSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YFQSPSR 7 0 Q16629-4;Q16629;H7BZZ6 Q16629-4 SRSF7 Serine/arginine-rich splicing factor 7 1 YFQS(0.952)PS(0.048)R 78.098 0.028827999999999996 8863900.0 42696.0 51157.0 51847.0 43060.0 62496.0 51566.0 51681.0 48322.0 46225.0 49089.0 True False 49923.58951556101 56235.52887516516 53083.22911084247 40647.48780240359 50250.35743128976 48861.78818324509 46785.40154196194 47053.598701391136 46900.95317589171 57988.44711168984 0.8609230286750852 0.9697712505880967 0.9154104266424038 0.7009583775215374 0.8665580806898316 0.8426124619121776 0.8068055599393782 0.8114305701403347 0.8087982264046002 1.0 15.823477884016318 -5.5679107445372225 24.999435712533128 0.8252024432292608 0.9221588938929873 0.19553932871992064 0.07403927813251977 156.91202419261947 87108.68116931578 0.018682694519594496 0.03235939598793564 2.7045141341383594e-06 5.5679107445372225 0.09695645066372649 YFQSPS(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 YFQSPSR 7 0 Q16629-4;Q16629;H7BZZ6 Q16629-4 SRSF7 Serine/arginine-rich splicing factor 7 1 YFQS(0.472)PS(0.528)R 88.177 0.019612 0.0 24449.0 19435.0 33643.0 34852.0 31536.0 31816.0 25448.0 29572.0 24220.0 26755.0 True False 32223.27342920832 25716.98367786067 33196.87183805432 26817.409858032373 27157.77075098402 29826.540490431973 27712.822700691697 25002.32689695699 25500.219753890007 25818.3155935882 1.248078067386036 0.9960751926143201 1.285787669521653 1.038697112552621 1.0518800365787018 1.1552473430078913 1.0733784161959035 0.9683949677633559 0.987679450328774 1.0 14.65610726075049 -7.605930011399509 3.820272692369926 0.9839565289003781 1.1224741144360906 0.36212205890697013 0.08498300231842629 0.25254327922462433 7.161637721192618 0.041237471791050806 0.02260266662234616 2.477821338034093e-08 7.605930011399509 0.13851758553571247 YFQSPS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YFQSPSR 7 0 Q16629-4;Q16629;H7BZZ6 Q16629-4 SRSF7 Serine/arginine-rich splicing factor 7 1 YFQS(0.013)PS(0.987)R;YFQS(0.1)PS(0.9)R 89.029 0.016874 24646500.0 102728.0 120949.0 112058.0 111773.0 115734.0 116635.0 118433.0 80752.0 87779.0 109313.0 True False 120117.82142951462 132956.0173959059 114729.88770233182 105510.7211829551 93056.75350347061 110518.4552758172 107214.1688593328 78632.34556381658 89062.60181344734 129130.58157876834 0.9302042936765058 1.0296245534587334 0.8884796018079401 0.8170854641322484 0.7206407062195948 0.8558658524154642 0.8302771314782103 0.6089366639756953 0.6897096003483889 1.0 16.978471184355605 -5.652550967804572 2.3177476452528865 0.770861589206268 0.9795959018323187 0.3554148341064308 0.10251963525145255 0.29874166994783313 3.24041987333342 0.030104941422339253 0.062405725061577745 2.2256098369987154e-06 5.652550967804572 0.2087343126260507 YFTWDPSR ddPTM_PC-9_AZD4547_30min_R2 1 YFTWDPSR 8 0 F5H6X6;Q14697;Q14697-2;E9PKU7 F5H6X6 GANAB Neutral alpha-glucosidase AB 0 92.47 0.033581 0.0 29068.0 33255.0 42767.0 35873.0 34874.0 31090.0 32973.0 48334.0 34365.0 33989.0 False True 38311.019348039874 44004.02841303099 42199.88163653859 27603.03408232511 30032.3470690581 29145.937385200235 35907.53312283506 40865.09090482617 36181.463742462 32799.05545544643 1.1680525190757636 1.3416248669967086 1.286618808089216 0.8415801522034837 0.9156467054319118 0.8886212416937275 1.0947733897889567 1.2459227967810376 1.1031251735773355 1.0 15.0013666483756 -5.735353431033945 24.891909977076228 1.017248847890141 1.273051578723707 0.4891932994319128 0.11815788998724926 204.3372909758426 194982.44525882427 0.03643228479618078 0.06307632389600032 1.8392745813414338e-06 5.735353431033945 0.25580273083356597 YFTWDPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YFTWDPSR 8 0 F5H6X6;Q14697;Q14697-2;E9PKU7 F5H6X6 GANAB Neutral alpha-glucosidase AB 0 90.37 0.043891 3498400.0 29053.0 33808.0 44314.0 44254.0 40832.0 35986.0 35336.0 47682.0 30702.0 28804.0 False True 33971.09907709375 37164.23481071181 45370.613821780884 41774.59185340382 32831.26271496455 34098.83081026756 31988.71826951427 46430.39802325505 31150.958667522464 34025.93718766147 0.9983883438605887 1.0922325109148898 1.3334126131941852 1.2277278836731698 0.9648893000034652 1.0021422958081674 0.9401274707905493 1.364558976500189 0.9155062649918271 1.0 15.054347278453475 -6.255616408511221 24.810170350230564 1.0434250834959056 1.1700663681818806 0.16483768577866342 0.1433376380020517 891.0701278723411 3796617.4488919387 0.04405935624830428 0.055254420288733355 5.551158036574037e-07 6.255616408511221 0.12664128468597502 YFVQGMGYMPS(ph)ASMTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YFVQGMGYMPSASMTR 16 0 Q92597;E5RJY1;E7ESM1;Q92597-3;Q92597-2 Q92597 NDRG1 Protein NDRG1 1 Y(0.196)FVQGMGY(0.035)MPS(0.74)AS(0.01)MT(0.019)R 65.038 0.017427 6320400.0 13821.0 16143.0 17746.0 28433.0 27298.0 25217.0 32428.0 28524.0 32692.0 22688.0 True False 16160.622322807034 17745.570354629686 18169.131942079788 26839.991191029745 21949.15286033265 23894.576128008583 29356.185081611064 27775.27522367619 33170.05865281236 26801.15480189082 0.6029823133466958 0.6621196170762663 0.6779234729392315 1.0014490565584204 0.8189629522524954 0.8915502449291036 1.0953328428795905 1.0363462107877772 1.2376354264582738 1.0 14.710007544078314 -5.858784103694313 0.49123746023957665 1.1173427990721427 0.49014801290330884 0.7638822095149038 0.09617508955273427 0.8516995735585623 0.3271019971424445 0.07540605170141437 0.27847415248601537 1.3842543479448393e-06 5.858784103694313 -0.6271947861688338 YGASSLNGCSPS(ph)PVHTMEQKPLQSLSSK ddPTM_PC-9_Lapatinib_30min_R1 1 YGASSLNGCSPSPVHTMEQKPLQSLSSK 28 1 Q9ULJ7-2;Q9ULJ7 Q9ULJ7-2 ANKRD50 Ankyrin repeat domain-containing protein 50 1 YGASS(0.002)LNGCS(0.077)PS(0.805)PVHT(0.104)MEQKPLQS(0.007)LS(0.002)S(0.003)K 52.36600000000001 0.023631 0.0 5766.3 4280.9 5663.2 3843.3 4245.5 5256.6 3181.1 3292.7 5628.8 3328.8 True False 5684.071504590092 4270.98783906771 5197.59355658418 4125.949102872958 3995.7880369741483 5031.787471733097 3345.8017927581586 3445.6908625923306 4994.825270108272 3904.178644652812 1.4558943178419954 1.0939529739289164 1.3312898895399772 1.0568033582489582 1.0234644468553724 1.2888210119751218 0.8569796869670885 0.8825648558145696 1.2793536681394475 1.0 11.93080335289539 -1.5228787470017304 0.4129895011304125 1.0247976928826024 7.609257918437153 0.3448404270540141 0.154603580875423 89.075306174705 1.1560404212849282 0.10613513835386912 482.0309845793852 0.029999999881090395 1.5228787470017304 6.584460225554551 YGEAGEGPGWGGAHPR ddPTM_PC-9_Lapatinib_30min_R1 1 YGEAGEGPGWGGAHPR 16 0 P26640;A2ABF4;A0A0G2JJT9;A0A140T954 P26640 VARS Valine--tRNA ligase 0 72.175 0.038733 0.0 49108.0 20138.0 24260.0 19169.0 28439.0 19166.0 20151.0 29792.0 19869.0 21703.0 False True 48407.71091469577 20091.37169827503 22265.436446308144 20578.752205909437 26766.27393322524 18346.314858128164 21194.320180399758 31176.24508104313 17631.143990154418 25454.3346325703 1.901747251046008 0.7893104254458474 0.8747208193695318 0.808457675400312 1.0515408994025024 0.720754053207621 0.8326409032621264 1.2247912008334845 0.6926578221217515 1.0 14.63562373409885 -4.7579475815188275 24.988233365175475 0.8905476790532627 1.901748677486193 0.7950951200459575 0.15433704927130426 41.27221520846139 295309.0024742259 0.03666439927798718 0.2612482308755987 1.7460328829031047e-05 4.7579475815188275 1.0112009984329302 YGEHEAS(ph)PDNGQNEFSDIIK ddPTM_PC-9_AZD4547_30min_R2 1 YGEHEASPDNGQNEFSDIIK 20 0 P46939;Q5SYY2 P46939 UTRN Utrophin 1 Y(0.004)GEHEAS(0.996)PDNGQNEFSDIIK 74.579 0.0014088 3405700.0 14070.0 16125.0 17591.0 25073.0 19363.0 18957.0 19671.0 18090.0 15709.0 20296.0 True False 18543.967325819507 21337.090908438557 17357.731846244773 19292.807223988446 16674.781679709027 17771.615793220994 21421.680892223598 15294.606166845395 16539.34566944089 19585.4432176216 0.9468239814524572 1.0894362037842957 0.8862567802717638 0.9850584952108788 0.8513864860972988 0.9073890029321036 1.0937552269917425 0.7809170309244974 0.8444713497502039 1.0 14.257494156325704 -5.276361385638512 24.877974414168857 0.9166503329108585 1.0181301009863797 0.1614527510689805 0.09058938209600557 1163.9344577876248 1940511.7299366675 0.023663400123315827 0.04961027800161796 5.292228830450016e-06 5.276361385638512 0.10147976807552117 YGGDEIPFS(ph)PYR ddPTM_PC-9_AZD4547_30min_R2 2 YGGDEIPFSPYR 12 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 YGGDEIPFS(1)PYR;YGGDEIPFS(1)PYR 118.76 0.00056982 17301400.0 89393.0 93021.0 113380.0 149139.0 135614.0 115525.0 109866.0 143412.0 102754.0 119894.0 True False 117818.11451009141 123088.21912520095 111876.50711882395 114757.30772458085 116786.33696803455 108301.20348746383 119643.86116135649 121250.97067991317 108185.3666635515 115696.54755289335 1.0183373402411005 1.0638884368518287 0.9669822435079752 0.9918818681440508 1.0094193771395208 0.9360798206874016 1.0341178167538538 1.048008546879763 0.935078608236707 1.0 16.8199862887298 -5.2596332891105835 24.999785109230018 0.9922932954814082 1.041112888716082 0.23595349579533043 0.03649372845145358 236.52347741767048 3273884.786776355 0.009313338068571108 0.022051422556443098 5.5000509280609634e-06 5.2596332891105835 0.048819593234673886 YGGDEIPFS(ph)PYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YGGDEIPFSPYR 12 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 1 YGGDEIPFS(0.998)PY(0.002)R;YGGDEIPFS(1)PYR 87.641 0.0084684 11922400.0 59931.0 78819.0 74375.0 76608.0 87828.0 68961.0 75840.0 85760.0 63895.0 67223.0 True False 70076.13460879447 86643.62942337587 76148.38206875825 72315.90212648718 70618.7338785732 65344.56376109777 68655.88616594869 83508.89087023097 64829.34349753595 79409.99776302483 0.8824598486693771 1.0910922033008692 0.9589268884756817 0.9106649560964876 0.8892927322490739 0.8228757788924626 0.8645748406999262 1.0516168394745211 0.816387675655143 1.0 16.27703303446328 -5.650880356105012 3.9748881483714036 0.9038363291734635 0.9945167861220653 0.12890313283054788 0.0831751147221972 0.37773346163028104 10.943215383195874 0.022485207928481434 0.04062520614394229 2.234187634964637e-06 5.650880356105012 0.09068045694860183 YGGELVPHFPAR ddPTM_PC-9_AZD4547_30min_R2 2 YGGELVPHFPAR 12 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 65.395 0.035024 5785100.0 51694.0 53279.0 79556.0 107327.0 91905.0 76670.0 67320.0 82311.0 65426.0 72018.0 False True 68131.61669800377 70500.3948223689 78501.03545903307 82584.41833562042 79145.57714577582 71875.81277977803 73311.34958387945 69591.72626861295 68884.28479017374 69496.67174057323 0.9803579796214539 1.0144427503743272 1.1295653949022562 1.188321919125896 1.1388398201459395 1.0342338845820702 1.0548900795932525 1.0013677565509116 0.9911882549903182 1.0 16.08465626704968 -7.4492515856480495 1.6218762777728317 0.9957207138581241 1.0903271802482646 0.2943931587400377 0.058170856137081964 0.5564476870476992 2.8395297498569074 0.04191679288216446 0.021633085632301017 3.5542536194483e-08 7.4492515856480495 0.09460646639014048 YGGELVPHFPAR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YGGELVPHFPAR 12 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 84.479 0.014705000000000001 0.0 28903.0 31778.0 34182.0 39016.0 39134.0 34774.0 33241.0 35480.0 30477.0 27925.0 False True 33795.70703972877 34932.70982651442 34997.02851595689 36830.06001157868 31465.97362576955 32950.39022387165 30092.17183600077 34548.687594167386 30922.668468180662 32987.581445821634 1.024497873396217 1.0589654741402441 1.060915259078194 1.1164825791205057 0.9538733137331953 0.9988725689996076 0.9122272842410031 1.047324055899936 0.9374033230950151 1.0 15.009635387096838 -6.273861065230532 24.963191116246097 0.9753762748746855 1.0644617363531137 0.5412227747885483 0.04071003905310807 567.484474501202 1140439.9808613583 0.012051504513284421 0.013763864993333983 5.322785127879658e-07 6.273861065230532 0.08908546147842822 YGGELVPHFPAR ddPTM_PC-9_Lapatinib_30min_R1 2 YGGELVPHFPAR 12 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 ; 87.363 0.007234 11393500.0 105662.0 103719.0 112695.0 98252.0 112742.0 108991.0 104129.0 87374.0 99337.0 91664.0 False True 104155.24050396234 103478.84502797648 103429.65211527995 105477.77983906372 106110.73721930035 104329.70900043016 109520.29011289003 91433.71501446891 88148.62099501578 107508.00026539751 0.9688138580090928 0.9625222752960289 0.9620647008590094 0.9811156339870342 0.9870031714602836 0.9704366999932905 1.018717582342941 0.850482892331295 0.8199261522622449 1.0 16.71408449717019 -7.766734586781846 24.999998551603152 0.8764033745811264 0.9775063189101355 0.42457436489846045 0.04639803591769683 105.67358091410962 498899.48900777684 0.023077123522404982 0.011602615731198505 1.711060687298454e-08 7.766734586781846 0.10110294432900913 YGGPNHIVGS(ph)PFK ddPTM_PC-9_AZD4547_30min_R2 2 YGGPNHIVGSPFK 13 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;A0A0A0MT44 O75369-2 FLNB Filamin-B 1 YGGPNHIVGS(1)PFK;YGGPNHIVGS(1)PFK 106.35 0.00063906 30876000.0 325640.0 305720.0 376550.0 440320.0 398200.0 394330.0 337540.0 377100.0 327660.0 366670.0 True False 429186.74626722466 404538.01131955616 371556.70096660114 338811.0268761856 342916.8034323257 369672.48276313866 367580.4060983764 318827.859895931 344979.4386688524 353832.99490566197 1.2129641736256205 1.1433021146810038 1.0500905973047105 0.9575450332621426 0.9691487463563235 1.0447654347828692 1.03885282432855 0.9010687654522892 0.9749781496799921 1.0 18.432709059964566 -5.235551505938641 1.8601502962280874 0.983729015054984 1.213061329053299 0.7942278439744935 0.039678561711049276 0.19176694763961138 1.1506955077923413 0.012205956665600735 0.055020311560511605 5.8136448024900156e-06 5.235551505938641 0.229332313998315 YGGPNHIVGS(ph)PFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YGGPNHIVGSPFK 13 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;A0A0A0MT44 O75369-2 FLNB Filamin-B 1 YGGPNHIVGS(1)PFK;YGGPNHIVGS(1)PFK 113.52 0.00019029 18876100.0 265480.0 257050.0 224920.0 264700.0 287230.0 264940.0 283330.0 265790.0 253670.0 209733.0 True False 310420.5205309899 282568.2252157316 230282.94581384968 249869.71716897836 230949.34339780713 251046.07999978604 256490.93126843683 258813.29412778319 257379.44385350836 247755.93265448548 1.252928707720977 1.1405104297130777 0.9294750012505121 1.0085317210847204 0.9321647353643134 1.013279792374897 1.035256465992009 1.0446300573101432 1.0388427074012536 1.0 17.91856007840248 -5.02303694516473 3.8131321505481757 1.0018364878713188 1.2400341861272017 0.814538903080219 0.03914737064721337 0.08859592173366697 2.778712522391773 0.010822463018948908 0.04186680430266833 9.483377853566256e-06 5.02303694516473 0.23819769825588288 YGGPNHIVGS(ph)PFK ddPTM_PC-9_Lapatinib_30min_R1 1 YGGPNHIVGSPFK 13 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;A0A0A0MT44 O75369-2 FLNB Filamin-B 1 YGGPNHIVGS(1)PFK 118.51 0.0010220000000000001 0.0 21550.0 22208.0 22865.0 18549.0 18130.0 17732.0 18015.0 18369.0 13798.0 17547.0 True False 21242.693048213998 22156.578740455447 20985.127961452414 19913.15533765006 17063.629044951424 16973.643695310882 18947.72855192802 19222.490799331386 12243.923940618597 20579.975570092196 1.0322020536839167 1.076608602619259 1.0196867284890758 0.9675985896984644 0.829137478168298 0.824765007008939 0.920687611479178 0.9340385625756733 0.594943560497324 1.0 14.328953649199807 -6.008941601679047 2.358169942856654 0.8492158203256852 1.0492310052565264 0.4246572618821559 0.10145484866125395 0.28331741553157597 3.15776766345356 0.030994505702512724 0.04727140383293012 9.796217034454033e-07 6.008941601679047 0.20001518493084114 YGGPYHIGGSPFK ddPTM_PC-9_Lapatinib_30min_R1 1 YGGPYHIGGSPFK 13 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 87.21600000000001 0.0060504 5963100.0 54829.0 63549.0 69920.0 70033.0 86764.0 86425.0 72679.0 61920.0 75517.0 65259.0 False True 54047.128405592855 63401.856194938926 64171.44749900507 75183.46044323932 81660.71210458716 82728.80421651507 76441.9629989219 64797.02925007346 67011.48023073588 76538.93119784853 0.7061390531556324 0.8283608773037207 0.8384157773659753 0.9822904405196696 1.0669173298683663 1.080872216554293 0.9987330865820953 0.846589157125503 0.8755215049647771 1.0 16.223906134667047 -5.456919562349199 1.8092465233197574 0.9811078586093656 0.7472221554090122 0.585497105675691 0.07398162243534163 0.31337594277522934 1.9407713503403254 0.02515560132413768 0.07742006545621938 3.492049873288924e-06 5.456919562349199 -0.2338857032003534 YGGSVGSQPPPVAPEPGPVPS(ph)SPSQEPPTKR ddPTM_PC-9_AZD4547_30min_R2 1 YGGSVGSQPPPVAPEPGPVPSSPSQEPPTKR 31 1 E9PS08;A0A087WTZ5;E9PJ81;E9PRQ7;Q04323;Q04323-2 E9PS08 UBXN1 UBX domain-containing protein 1 1 YGGSVGSQPPPVAPEPGPVPS(0.483)S(0.483)PS(0.034)QEPPTKR 138.77 4.3464999999999997e-16 48707000.0 52292.0 49606.0 70548.0 95996.0 93286.0 74596.0 60906.0 88361.0 58152.0 71666.0 True False 68919.76825883109 65640.16940179864 69612.48742475566 73865.60532341551 80334.84913357106 69931.50032764222 66326.51600944386 74706.83778378266 61225.796000339025 69156.9951534327 0.9965697339209822 0.9491472157829939 1.0065863513923992 1.0680858119924994 1.161630128020152 1.0111992311477849 0.9590716869969683 1.0802499099048042 0.885316024279288 1.0 16.07758756531075 -10.319754927513303 10.155277679478983 1.0000006018705867 1.017339371045624 0.0 0.07308414563229802 0.0 0.0 0.07263771578881935 0.01761723380005282 4.789002596261513e-11 10.319754927513303 0.017338769175037294 YGGSVGSQPPPVAPEPGPVPS(ph)SPSQEPPTKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YGGSVGSQPPPVAPEPGPVPSSPSQEPPTKR 31 1 E9PS08;A0A087WTZ5;E9PJ81;E9PRQ7;Q04323;Q04323-2 E9PS08 UBXN1 UBX domain-containing protein 1 1 YGGSVGSQPPPVAPEPGPVPS(0.481)S(0.481)PS(0.035)QEPPT(0.002)KR 130.38 2.5445e-16 95232000.0 59197.0 48557.0 53939.0 62430.0 82121.0 89856.0 78063.0 79278.0 67484.0 60919.0 True False 69217.88290595537 53377.41805796654 55225.11032479665 58932.249500790844 66029.97956053111 85143.79317755246 70668.30751282233 77197.03650198416 68470.82583281492 71963.13246546137 0.9618520002471601 0.7417328322052265 0.7674083719368648 0.8189227939608564 0.9175528815706032 1.1831585182651287 0.9820071068576609 1.0727303531295667 0.9514708919275773 1.0 16.134970366222614 -6.526476742463382 5.71105209248121 1.040835850436385 0.8182350203303763 0.6187387940795945 0.07978847373877802 0.10243727574697191 12.141869643127173 0.025628362335099172 0.026823728967136595 2.9752485864869825e-07 6.526476742463382 -0.22260083010600873 YGGSVGSQPPPVAPEPGPVPS(ph)SPSQEPPTKR ddPTM_PC-9_Lapatinib_30min_R1 3 YGGSVGSQPPPVAPEPGPVPSSPSQEPPTKR 31 1 E9PS08;A0A087WTZ5;E9PJ81;E9PRQ7;Q04323;Q04323-2 E9PS08 UBXN1 UBX domain-containing protein 1 1 YGGSVGSQPPPVAPEPGPVPS(0.482)S(0.482)PS(0.037)QEPPTKR;YGGSVGSQPPPVAPEPGPVPS(0.477)S(0.477)PS(0.046)QEPPTKR;YGGSVGSQPPPVAPEPGPVPS(0.481)S(0.481)PS(0.038)QEPPT(0.001)KR 166.65 9.9484e-19 129622000.0 238901.0 208446.0 241035.0 202796.0 244890.0 240447.0 235024.0 232776.0 280127.0 217088.0 True False 235494.22793092247 207963.35609388447 221218.03272200684 217710.29434762464 230486.0516722646 230163.64231933322 247192.3927387359 243591.62275056666 248576.1473919167 254611.37154842322 0.9249163794168362 0.8167873839614936 0.868845846816133 0.8550690137035747 0.9052464949643054 0.9039802147075728 0.9708615575000886 0.9567193376680713 0.9762963291081493 1.0 17.957937329301195 -7.064588599728051 1.0160862251454905 0.9838029285653509 0.8618563781760782 0.7572711609038552 0.027626431431643887 0.24631277964212248 0.5175165865298852 0.01737318885830026 0.011755053560100603 8.618097443322275e-08 7.064588599728051 -0.12194655038927271 YGGSVGSQPPPVAPEPGPVPSS(ph)PSQEPPTKR ddPTM_PC-9_AZD4547_30min_R2 3 YGGSVGSQPPPVAPEPGPVPSSPSQEPPTKR 31 1 E9PS08;A0A087WTZ5;E9PJ81;E9PRQ7;Q04323;Q04323-2 E9PS08 UBXN1 UBX domain-containing protein 1 1 YGGSVGSQPPPVAPEPGPVPS(0.358)S(0.595)PS(0.046)QEPPTKR;YGGSVGSQPPPVAPEPGPVPS(0.396)S(0.57)PS(0.033)QEPPTKR;YGGSVGSQPPPVAPEPGPVPS(0.357)S(0.605)PS(0.036)QEPPT(0.001)KR 162.15 9.4645e-17 268133000.0 292428.0 249069.0 407920.0 546080.0 470360.0 405048.0 337131.0 466540.0 374409.0 421280.0 True False 385414.0211197398 329575.6834402408 402510.7142698066 420189.6928518966 405058.6330045938 379720.28452880617 367135.0058907145 394446.96302266663 394199.4953688769 406531.11542765243 0.9480554046011991 0.810702233932431 0.9901104712400265 1.0335978647289419 0.9963779342658442 0.9340497445794709 0.9030920191791594 0.970274963105164 0.9696662331841359 1.0 18.63300625319519 -5.282968656721643 24.843526329634667 0.9724607261043956 0.8793788052436015 0.4068782050340243 0.04594852224931318 661.196900809467 762981.5350236315 0.012558685274954282 0.026182200340257197 5.212323273794998e-06 5.282968656721643 -0.09308192086079414 YGGSVGSQPPPVAPEPGPVPSS(ph)PSQEPPTKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 YGGSVGSQPPPVAPEPGPVPSSPSQEPPTKR 31 1 E9PS08;A0A087WTZ5;E9PJ81;E9PRQ7;Q04323;Q04323-2 E9PS08 UBXN1 UBX domain-containing protein 1 1 YGGSVGSQPPPVAPEPGPVPS(0.37)S(0.557)PS(0.057)QEPPT(0.016)KR;YGGSVGSQPPPVAPEPGPVPS(0.388)S(0.558)PS(0.043)QEPPT(0.01)KR;YGGSVGSQPPPVAPEPGPVPS(0.379)S(0.583)PS(0.036)QEPPT(0.002)KR 151.06 1.7307e-17 154718000.0 174490.0 170704.0 173621.0 216685.0 244875.0 243430.0 242519.0 239678.0 229010.0 195570.0 True False 204027.7106654071 187650.36497656652 177760.78310130956 204544.84195224824 196893.50159989588 230664.10226597654 219545.8446344902 233386.70645983255 232358.8380056451 231025.29286873192 0.8831401450980313 0.8122503066501426 0.7694429510032603 0.885378563586413 0.852259504381498 0.9984365755010184 0.9503108595093771 1.0102214504817981 1.0057722906455568 1.0 17.817691282349756 -6.673557679631868 1.755655838759554 0.9964143614147971 0.8274427483724224 0.8043683031353874 0.03708064796734557 0.1482523147335563 0.9421507709500001 0.01492651485259845 0.014558270957121866 2.12051974336667e-07 6.673557679631868 -0.16897161304237474 YGGSVGSQPPPVAPEPGPVPSS(ph)PSQEPPTKR ddPTM_PC-9_Lapatinib_30min_R1 2 YGGSVGSQPPPVAPEPGPVPSSPSQEPPTKR 31 1 E9PS08;A0A087WTZ5;E9PJ81;E9PRQ7;Q04323;Q04323-2 E9PS08 UBXN1 UBX domain-containing protein 1 1 YGGSVGSQPPPVAPEPGPVPS(0.369)S(0.578)PS(0.052)QEPPT(0.001)KR;YGGSVGSQPPPVAPEPGPVPS(0.373)S(0.616)PS(0.011)QEPPTKR 127.14 3.8207e-16 77997000.0 81449.0 82191.0 78857.0 67619.0 77597.0 81254.0 77676.0 71801.0 87417.0 72826.0 True False 80287.52232408262 82000.69178929993 72373.68185682264 72591.92683037133 73032.89702157167 77778.9558323253 81697.683208413 75137.1365824375 77571.17691818048 85413.87706545468 0.9399821795064564 0.9600394526812178 0.8473293139633619 0.8498844605162041 0.8550472069732279 0.9106126370158966 0.9564919192908914 0.8796830112846665 0.9081800239407919 1.0 16.38218286095359 -6.995272339168451 24.730718210337177 0.9271323192247669 0.8889880427365735 0.17084891175711292 0.045659102418140356 262.7981865244527 1374701.1897124967 0.0172459312537106 0.015154145262063047 1.0109453077110152e-07 6.995272339168451 -0.03814427648819341 YGLQDS(ph)DEEEEEHPSK ddPTM_PC-9_AZD4547_30min_R2 1 YGLQDSDEEEEEHPSK 16 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;P52948-4;P52948-3 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 YGLQDS(1)DEEEEEHPSK 123.61 2.1782e-05 13200000.0 27989.0 26443.0 54170.0 71976.0 60459.0 57360.0 41237.0 62761.0 46790.0 56390.0 True False 36888.91979263413 34990.18262895138 53451.67040595078 55383.04521811488 52065.3114483049 53773.27013236042 44907.013113345776 53062.729554305355 49263.22387632181 54415.80326378016 0.6779082101171123 0.6430150899240935 0.9822821165910985 1.0177750193201416 0.9568049780671017 0.9881921593933831 0.8252568265079061 0.9751345449608492 0.9053109744152583 1.0 15.731738074762498 -5.260171337903378 24.999987214629382 0.9541226253407351 0.6604616223192127 0.8325928815779916 0.05306268992649618 40.439375699965915 797257.1109695645 0.014015067723919108 0.03314982206911818 5.49324111697243e-06 5.260171337903378 -0.2936610030215224 YGLQDS(ph)DEEEEEHPSK ddPTM_PC-9_Lapatinib_30min_R1 2 YGLQDSDEEEEEHPSK 16 0 P52948-6;P52948-2;P52948-5;P52948;A0A3B3ITD8;P52948-4;P52948-3 P52948-6 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 YGLQDS(0.502)DEEEEEHPS(0.498)K;YGLQDS(1)DEEEEEHPSK 98.443 0.0011618 18620500.0 106116.0 116110.0 158690.0 109715.0 142522.0 150671.0 105962.0 141177.0 168518.0 104749.0 True False 104602.76638070882 115841.15442877715 145643.12076111426 117783.80709851075 134139.1361690331 144227.15256125573 111448.19388395199 147736.59881197702 149537.72826678952 122854.72508073098 0.8514346217613663 0.942911673544953 1.185490591960614 0.958724273902465 1.0918516652972594 1.1739650425857076 0.9071543142578891 1.202530864929253 1.2171915094720571 1.0 16.90659382028867 -5.056053913862551 4.8013108717184885 1.0905586216508873 0.8684753302880123 0.3817044820491615 0.10213956391507556 0.18922733137262412 9.148608025836847 0.0258793333213244 0.08014641540406535 8.789134006444528e-06 5.056053913862551 -0.22208329136287508 YGMGTS(ph)VER ddPTM_PC-9_Lapatinib_30min_R1 2 YGMGTSVER 9 0 P08559-3;P08559;P08559-2;P08559-4 P08559-3 PDHA1 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial 1 YGMGT(0.068)S(0.932)VER;YGMGT(0.041)S(0.959)VER 82.749 0.015321000000000001 20937800.0 165338.0 145890.0 187738.0 176925.0 141193.0 129384.0 86620.0 101805.0 190309.0 90125.0 True False 162980.24980072412 145552.2006684549 172302.90632963722 189936.6547044981 132888.30533611853 123850.54792883524 91104.75976508498 106535.23195742487 168874.39637738664 105702.98616598609 1.5418698724820807 1.3769923248894154 1.6300665911090613 1.796890150352416 1.2571859145723958 1.1716844757285467 0.8618939073492453 1.0078734368973445 1.5976312732754974 1.0 16.689656608640902 -6.463615226621804 4.768907796007954 1.1195820053728534 1.574045289022231 0.528969802509576 0.2045832102676379 0.18066948305544162 8.42011646341863 0.06767553257171563 0.0753312124366455 3.4386246599602324e-07 6.463615226621804 0.4544632836493776 YGPADVEDTTGSGATDSKDDDDIDLFGS(ph)DDEEESEEAKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YGPADVEDTTGSGATDSKDDDDIDLFGSDDEEESEEAKR 39 2 P24534;C9JZW3 P24534 EEF1B2 Elongation factor 1-beta 1 YGPADVEDT(0.081)T(0.081)GS(0.242)GAT(0.073)DS(0.257)KDDDDIDLFGS(0.267)DDEEESEEAKR 56.648 4.7613e-05 17669000.0 57149.0 46286.0 28562.0 52641.0 47342.0 45397.0 45262.0 45549.0 35637.0 39189.0 True False 66823.196955799 50880.96818648268 29243.02640198819 49691.695434424684 38065.67494739058 43016.30140314894 40974.45569149747 44353.38701315478 36158.12370641975 46293.65548004668 1.4434633917514008 1.0990916068058874 0.6316854026485857 1.0734018499758053 0.822265482227851 0.9292051136832274 0.8850987304115168 0.9580878103754804 0.7810600249963948 1.0 15.49852686602274 -4.892563912901355 3.582788965657686 0.8879834011910303 1.4506006699476577 0.6786417706939074 0.11793813261805748 0.129891971080345 2.883698412306129 0.02750864408587974 0.1633733440581199 1.280666611501559e-05 4.892563912901355 0.5626172687566274 YGPADVEDTTGSGATDSKDDDDIDLFGS(ph)DDEEESEEAKR ddPTM_PC-9_Lapatinib_30min_R1 1 YGPADVEDTTGSGATDSKDDDDIDLFGSDDEEESEEAKR 39 2 P24534;C9JZW3 P24534 EEF1B2 Elongation factor 1-beta 1 Y(0.001)GPADVEDT(0.088)T(0.088)GS(0.081)GAT(0.035)DS(0.191)KDDDDIDLFGS(0.515)DDEEES(0.001)EEAKR 42.192 0.0078196 5014500.0 12220.0 9313.0 11108.0 9849.1 10949.0 7500.7 7439.9 8787.7 8439.8 10283.0 True False 12045.740559126458 9291.43632068902 10194.743118119985 10573.435669634451 10305.001346562229 7179.9125459857005 7825.1016182897165 9196.008623076077 7489.220848965998 12060.402848763777 0.9987842620332684 0.7704084546099068 0.8453070138668687 0.8767066740824712 0.8544491818213616 0.5953294127916847 0.6488258905125884 0.7624959745037615 0.620976010741935 1.0 13.557990477351877 -6.663692247665802 9.338401670163941 0.7060592080644575 0.8635759872303006 0.2616511683621966 0.11826178185151345 0.3613858765000237 31.368919460851316 0.03674062951239654 0.036714811254351276 2.169240740557907e-07 6.663692247665802 0.15751677916584306 YGPSLMPGGNK ddPTM_PC-9_Lapatinib_30min_R1 1 YGPSLMPGGNK 11 0 P52209-2;P52209;K7EMN2;K7EM49;K7EPF6 P52209-2 PGD 6-phosphogluconate dehydrogenase, decarboxylating 0 87.30799999999999 0.03753 0.0 21022.0 17195.0 14825.0 14370.0 19151.0 16503.0 21319.0 14235.0 15047.0 16963.0 False True 20722.222425037344 17155.186033957645 13606.145726154915 15426.817736914747 18024.575832314666 15797.20516037197 22422.79350533185 14896.410067422421 13352.248408065518 19895.031948223274 1.0415777405619067 0.8622849201048752 0.6838966512627296 0.7754105536026766 0.9059837591225558 0.7940276347122297 1.1270549131907435 0.7487502461011502 0.6711348060568428 1.0 14.28012059531929 -10.791080101577403 3.7373125975594235 1.0002628220871568 0.8449344811492794 0.09909455239012555 0.13967983487852934 205909431.26458204 249914832.09236744 624964.374886803 0.0355419621156381 1.6177816253519467e-11 10.791080101577403 -0.1553283409378774 YGQCWVFAAVACT(ph)VLR ddPTM_PC-9_AZD4547_30min_R2 1 YGQCWVFAAVACTVLR 16 0 P21980;P21980-2 P21980 TGM2 Protein-glutamine gamma-glutamyltransferase 2 1 YGQCWVFAAVACT(1)VLR 74.475 0.032125 6627000.0 8819.7 6790.7 10751.0 14821.0 9878.6 11002.0 9165.4 13132.0 8464.7 9199.2 True False 11624.181138843654 8985.660975623796 10608.434715421386 11404.24743216739 8507.126907048163 10314.043200771088 9981.102844267505 11102.751143339621 8912.126760972451 8877.13880801856 1.3094513209981282 1.0122249037614697 1.195028594780897 1.284676028932446 0.9583185631122302 1.1618657118952107 1.1243603440392025 1.2507128009883888 1.003941354721443 1.0 13.115879040896077 -14.522878744078815 0.12432160502379434 0.5122342302302927 1.2105804553860842 0.17975764803534267 0.11169962462501837 294.59315923785016 2.3384244988499083 35.70476831236588 0.9462381437955246 3.000000008299824e-15 14.522878744078815 0.6983462251557915 YGQFSGLNPGGRPIT(ph)PPRNSAK ddPTM_PC-9_Lapatinib_30min_R1 1 YGQFSGLNPGGRPITPPRNSAK 22 2 P62136-3;P62136;P62136-2 P62136-3 PPP1CA Serine/threonine-protein phosphatase PP1-alpha catalytic subunit 1 YGQFS(0.001)GLNPGGRPIT(0.85)PPRNS(0.149)AK 41.912 0.046185000000000004 7251600.0 48899.0 18693.0 21245.0 18383.0 17463.0 14496.0 13244.0 13963.0 23343.0 12837.0 True False 48201.69129302166 18649.717506994486 19498.318108071577 19734.9471438903 16435.86067357897 13876.03987182645 13929.709516610314 14611.7719544376 20713.86552731263 15055.858345772689 3.2015239640292905 1.238701711897473 1.2950651939114597 1.3107819355534374 1.0916588278205839 0.9216372493118267 0.9252019510745084 0.9705040801303914 1.3758010371510019 1.0 13.878037339082638 -4.758008454693427 4.737067723878585 1.1121412966732764 3.363212858901296 0.9403193281368702 0.15718894582650839 0.04630180090029072 2.4750402422413487 0.04350867997457024 0.35374013828621964 1.7457881661948553e-05 4.758008454693427 2.2510715622280197 up YGRPPDSHHSR ddPTM_PC-9_AZD4547_30min_R2 1 YGRPPDSHHSR 11 1 J3QL05;J3KP15;Q01130-2;Q01130 J3QL05 SRSF2 Serine/arginine-rich splicing factor 2 0 94.82 0.014944999999999998 0.0 0.0 0.0 0.0 1101.7 678.2 567.16 0.0 0.0 0.0 769.39 False True 0.0 0.0 0.0 847.7200860953244 584.0436365841374 531.6953955416582 0.0 0.0 0.0 742.4538902840902 0.0 0.0 0.0 1.1417814590087951 0.7866396071554838 0.7161325470841184 0.0 0.0 0.0 1.0 9.536157620638832 -5.612889748429169 23.939742193848907 0.48378410389255794 8.655744569895786e-05 0.2656508530033095 0.39335730789230383 21.747806422271076 5774.531114338352 0.11805039455044088 0.2044693279761429 2.4384297684175743e-06 5.612889748429169 -0.483697546446859 YGS(ph)FEEAEASYPILNR ddPTM_PC-9_AZD4547_30min_R2 1 YGSFEEAEASYPILNR 16 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 YGS(1)FEEAEASYPILNR 134.02 3.9192000000000005e-06 17059000.0 19941.0 25115.0 21732.0 33113.0 35595.0 26847.0 20749.0 21173.0 25632.0 34336.0 True False 26281.82320143332 33232.9325994068 21443.819480563452 25479.309440750207 30653.24866442404 25168.25284594631 22595.620803860897 17901.199357137517 26986.85519123489 33133.90709106501 0.7932002443660063 1.0029886456815862 0.647186563951767 0.7689799265363738 0.9251323298570511 0.7595920631024301 0.6819485773820528 0.5402682909666517 0.8144785073811064 1.0 15.016020713018287 -6.990514625869857 24.539274157437774 0.7208496316902009 0.8258171445053312 0.02819676926265824 0.14080861829136054 378.5257348153326 979264.142202847 0.04869839989529914 0.042889417814073225 1.0220811390771939e-07 6.990514625869857 0.10496751281513028 YGS(ph)FEEAEASYPILNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 7 YGSFEEAEASYPILNR 16 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 Y(0.045)GS(0.955)FEEAEASYPILNR;YGS(1)FEEAEASYPILNR;YGS(0.808)FEEAEAS(0.192)Y(0.001)PILNR;YGS(0.992)FEEAEAS(0.008)YPILNR;YGS(1)FEEAEASYPILNR;YGS(1)FEEAEASYPILNR;Y(0.007)GS(0.993)FEEAEASYPILNR 151.22 2.9818e-05 34818200.0 43767.700000000004 43503.4 44945.1 68559.4 58896.399999999994 48878.399999999994 46150.79999999999 47881.6 38719.5 49810.5 True False 51176.70715852115 47822.13004804543 46016.76163924095 64718.239090573705 47356.073211344985 46315.13065849448 41779.06212114272 46624.758734748786 39285.699437402654 58840.74935029899 0.8697494121607597 0.8127382906588091 0.7820560096080272 1.0998880844512027 0.8048176431169864 0.7871267985178904 0.7100362008039319 0.7923889353817665 0.6676614399235729 1.0 15.844527999308003 -6.504673297112353 24.92172033805591 0.7758894002289013 0.8870497082747447 0.1439331133431918 0.11349861150856581 1285.417290651994 1759630.450331281 0.03483158332693554 0.03874425013894666 3.1284318800777996e-07 6.504673297112353 0.11116030804584343 YGS(ph)FEEAEASYPILNR ddPTM_PC-9_Lapatinib_30min_R1 2 YGSFEEAEASYPILNR 16 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 YGS(1)FEEAEASYPILNR;YGS(1)FEEAEASYPILNR 144.8 8.164500000000001e-06 32169000.0 22760.2 20499.2 30611.0 34860.0 27993.0 32668.0 22381.0 22072.9 30022.1 41875.0 True False 22435.635374290505 20451.7353618671 28094.281741877083 37423.72068955099 26346.506776355487 31270.86579282746 23539.778668925963 23098.487515083118 26640.694951271602 49113.037955069856 0.4568162815506409 0.4164217123073712 0.5720330672189045 0.761991565738356 0.5364462854132155 0.6367121052750804 0.47929795526924823 0.47031274131757717 0.5424363073537284 1.0 15.583818444745216 -10.619971513259078 4.36404067592636 1.000052313818016 0.5438417498875858 0.6766130051389574 0.09510382654987715 23662060.233381417 11516414.008525066 11190.64250471646 0.024899612942470006 2.3989902711755243e-11 10.619971513259078 -0.45621056393043014 YGS(ph)QEHPIGDK ddPTM_PC-9_Lapatinib_30min_R1 1 YGSQEHPIGDK 11 0 Q14644-2;Q14644 Q14644-2 RASA3 Ras GTPase-activating protein 3 1 Y(0.008)GS(0.992)QEHPIGDK 82.65100000000001 0.039473 0.0 12800.0 11179.0 10941.0 9221.0 9360.6 8608.4 9123.9 9521.8 12171.0 8236.1 True False 12617.469652767488 11153.115712335712 10041.473213481344 9899.143100354266 8810.027911647678 8240.238799160516 9596.290898414436 9964.217589039888 10800.17381368814 9659.698911086589 1.3061969911180378 1.1546028313092767 1.0395223811744885 1.0247879557604909 0.9120395979978496 0.8530533793038895 0.9934358189364082 1.0315246552461173 1.118065264052134 1.0 13.237762506202236 -4.913608158388619 1.3255174538182988 0.9823804855460078 1.3970969824049824 0.6944628291863781 0.0666459734747004 0.6460587394158859 1.2001341751179029 0.02229033230950971 0.3410439543593179 1.2200899269588384e-05 4.913608158388619 0.4147164968589746 YGSFEEAEAS(ph)YPILNR ddPTM_PC-9_AZD4547_30min_R2 1 YGSFEEAEASYPILNR 16 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 YGS(0.148)FEEAEAS(0.85)Y(0.002)PILNR 136.33 1.0077e-05 18567000.0 17506.0 17922.0 16371.0 25222.0 20638.0 18885.0 19385.0 23496.0 18800.0 17892.0 True False 23072.543852579704 23714.93601618828 16153.909843378633 19407.457576015513 17772.769937811026 17704.11796460296 21110.227446279016 19865.233084367013 19793.729619039324 17265.60652590096 1.3363297615967027 1.3735362253629708 0.935612068950221 1.1240530442357446 1.029374201893762 1.0253979747565873 1.2226751150972053 1.1505667672065982 1.1464253855979984 1.0 14.075613395266364 -5.242272145092643 24.847857285941 1.0876564561617978 1.354933066088067 0.6480359265010539 0.08107558971498392 481.4736293015894 624166.3170479093 0.021159790526942366 0.05579768176979837 5.724372081032718e-06 5.242272145092643 0.2672766099262691 YGVIILDEAHER ddPTM_PC-9_Lapatinib_30min_R1 2 YGVIILDEAHER 12 0 O43143 O43143 DHX15 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 0 ; 111.52 0.00089195 1884200.0 41725.0 34374.0 41372.0 32707.0 36945.0 44159.0 35995.0 37417.0 37447.0 33730.0 False True 41129.99384857214 34294.40911493226 37970.55386053833 35112.38188735352 34771.96773666466 42270.42250965675 37858.64497511236 39155.53041747417 33229.32452560838 39560.18555760014 1.0396815199131546 0.8668920186180411 0.9598173852155653 0.88756868534475 0.87896371684193 1.0685092072712974 0.9569885591155705 0.9897711516156367 0.8399688741910994 1.0 15.271761572643483 YGVSGYPTLK ddPTM_PC-9_Lapatinib_30min_R1 2 YGVSGYPTLK 10 0 H7BZJ3;P30101 H7BZJ3;P30101 PDIA3 Protein disulfide-isomerase A3 0 ; 111.46 0.0073392 11063300.0 84431.0 73179.0 88678.0 72738.0 74324.0 75358.0 63151.0 66307.0 72619.0 67313.0 False True 83226.9984572507 73009.55852160422 81387.23714697904 78087.3951668548 69952.40844660619 72135.11400807799 66420.64977978393 69387.86528560429 64439.88350802873 78947.96236106548 1.0542007161200084 0.9247807839257182 1.0308972481741534 0.989099564213261 0.8860571743027582 0.9137045700834027 0.8413219010772137 0.8789063480607839 0.8162323837227792 1.0 16.26861441030219 -6.254960396500547 4.577290452756854 0.8814170065570833 0.9977697905790232 0.48615157500593686 0.05530123015891489 0.16137255531475936 9.271542243033567 0.016143244465319662 0.01989040567279362 5.559549527286925e-07 6.254960396500547 0.11635278402193983 YGVYEDENYEVGS(ph)DDEEIPFK ddPTM_PC-9_AZD4547_30min_R2 1 YGVYEDENYEVGSDDEEIPFK 21 0 O15541 O15541 RNF113A RING finger protein 113A 1 YGVYEDENY(0.001)EVGS(0.999)DDEEIPFK 66.138 0.020481 0.0 6953.1 6454.1 8337.3 10133.0 10515.0 10091.0 5226.0 10332.0 7580.3 7912.6 True False 9164.041166535582 8540.261608195557 8226.74195450495 7796.99340328939 9055.173752111772 9460.008174784674 5691.103875896525 8735.426805740548 7980.979182510834 7635.582282407997 1.200175812085619 1.1184820348111362 1.0774216883837342 1.0211393335716223 1.1859179060874563 1.238937362587273 0.7453398660909655 1.144041997408179 1.0452351749124116 1.0 12.898522464462296 YGVYEDENYEVGS(ph)DDEEIPFK ddPTM_PC-9_Lapatinib_30min_R1 1 YGVYEDENYEVGSDDEEIPFK 21 0 O15541 O15541 RNF113A RING finger protein 113A 1 YGVYEDENYEVGS(0.999)DDEEIPFK 62.739 0.03243 0.0 5852.1 6231.1 5649.1 4575.7 5774.8 5333.5 4833.8 4801.2 5409.2 5504.4 True False 5768.6479808562935 6216.672270787644 5184.65280415661 4912.212242087737 5435.137617693626 5105.3986379957505 5084.070512034953 5024.281279642328 4799.958934598787 6455.828205848035 0.8935566122454657 0.9629550342055647 0.8030964639765465 0.7608957496170656 0.8418962593784927 0.7908200892599662 0.7875163882814492 0.7782551083207363 0.7435078477228881 1.0 12.656386472653748 -5.271778978343385 24.09051048043163 0.802762395628623 0.9282558216172366 0.2924104607235867 0.07005847586159746 387.85531021879933 903677.2042146043 0.016867933633393627 0.03578453497787993 5.3483647975516425e-06 5.271778978343385 0.12549342598861368 YGYLS(ph)LPKPMK ddPTM_PC-9_Lapatinib_30min_R1 1 YGYLSLPKPMK 11 1 Q9UBT7-3;Q9UBT7-2;Q9UBT7 Q9UBT7-3 CTNNAL1 Alpha-catulin 1 Y(0.018)GY(0.002)LS(0.98)LPKPMK 53.034 0.045517 10158000.0 88517.0 73680.0 69783.0 66554.0 62469.0 48997.0 50069.0 57758.0 65623.0 46712.0 True False 87254.73134797018 73509.39848688581 64045.711110169854 71448.60317763544 58794.69623877938 46901.512527585604 52661.327830501454 60441.64753594548 58231.84669917473 54786.10696017245 1.5926433942714942 1.3417525457745068 1.1690137274533634 1.3041372556289867 1.073167989131278 0.8560840536028839 0.9612168258055708 1.1032294661835418 1.0628944075458255 1.0 15.741522470530475 -4.165157824892966 0.5403664589214088 0.9983497289977898 2.4603886680198706 0.7992191805915401 0.09149040760226325 3.623516442658731 0.4928419301199357 0.05531280432263345 3.849547977537541 6.836631553554806e-05 4.165157824892966 1.4620389390220807 YHCAIPGS(ph)KK ddPTM_PC-9_Lapatinib_30min_R1 1 YHCAIPGSKK 10 1 Q709C8-3;Q709C8 Q709C8-3 VPS13C Vacuolar protein sorting-associated protein 13C 1 YHCAIPGS(1)KK 56.951 0.038222000000000006 7365000.0 34453.0 27255.0 24490.0 24770.0 30406.0 26908.0 25946.0 30018.0 23490.0 26163.0 True False 33961.69390209359 27191.8927220422 22476.526734133815 26591.668430297712 28617.578860496036 25757.207565611647 27289.356925246975 31412.745866096688 20844.308839334008 30685.239689993854 1.1067762300441848 0.8861554609563373 0.7324865948973891 0.8665947764771408 0.9326170872254238 0.8394005660646937 0.889331717820857 1.0237086685146561 0.6792943138107904 1.0 14.905257232316544 -4.766566099960182 5.599035274707191 0.8689967940512989 1.1168908735351906 0.3295934789789089 0.10054686984568868 0.16015056765428867 16.537912485683986 0.02390647675391128 0.15284698019009763 1.7117246310466725e-05 4.766566099960182 0.24789407948389164 YHEEFEK ddPTM_PC-9_AZD4547_30min_R2 4 YHEEFEK 7 0 Q14847;Q14847-2;C9J9W2;Q14847-3 Q14847 LASP1 LIM and SH3 domain protein 1 0 ;;; 135.77 0.0031263000000000003 74531100.0 494648.0 445819.0 566434.0 708490.0 663720.0 540106.0 494284.0 601712.0 485725.0 561564.0 False True 651935.7746824425 589921.2732842894 558922.7150585986 545158.5765613838 571573.9346411425 506333.0864384349 538274.3184450124 508731.236366217 511399.43187275867 541903.8152867793 1.203047028442554 1.088608820685455 1.0314057574272895 1.0060061604712676 1.0547516339936849 0.9343597002919787 0.9933023227750369 0.9387851165007813 0.9437088602192669 1.0 19.04767727892547 -1.5228787452803425 0.4691697225878652 0.9618829521593629 7.147629630687165 0.8378177203841146 0.03135173359637624 34.67269798685561 0.3992894252176244 0.018455365428590793 207.8794101263816 0.02999999999999966 1.5228787452803425 6.185746678527802 YHEEFEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 YHEEFEK 7 0 Q14847;Q14847-2;C9J9W2;Q14847-3 Q14847 LASP1 LIM and SH3 domain protein 1 0 ;; 116.9 0.0063712 40019600.0 259090.0 261407.0 275183.0 311363.0 340851.0 303423.0 329049.0 296896.0 284337.0 237265.0 False True 302948.8197392429 287357.7593813216 281744.4063573384 293918.34056246525 274063.69336937653 287510.96373433626 297879.0966115404 289102.7945873151 288494.89071224496 280279.26631129277 1.0808820207298964 1.025255143426011 1.0052274292898227 1.0486624445349597 0.9778236434549072 1.0258017566487119 1.0627939074191108 1.0314812022742434 1.0293122802449022 1.0 18.09650549923449 YHEEFEK ddPTM_PC-9_Lapatinib_30min_R1 4 YHEEFEK 7 0 Q14847;Q14847-2;C9J9W2;Q14847-3 Q14847 LASP1 LIM and SH3 domain protein 1 0 ;;; 143.85 0.0015604000000000002 75871800.0 479860.0 437939.0 460230.0 442113.0 467266.0 408353.0 422231.0 409262.0 434025.0 371569.0 False True 473017.1084044527 436924.9791523923 422391.66593917593 474627.4648657334 439782.332560302 390888.6941073366 444092.05518784997 428277.80660438666 385140.5340141309 435794.2065654297 1.0854139437336334 1.0025947398334514 0.9692457117962133 1.089109166012911 1.0091513974596025 0.8969570687687629 1.0190407501921999 0.9827524096286614 0.8837669895832043 1.0 18.733287491875302 -6.536850908261866 24.899297470960228 0.9586362767151818 1.0318244853863245 0.3540503953534683 0.05125897613600319 272.7979023910701 486140.4625517562 0.016713381576419724 0.01672106697324231 2.9050197661697216e-07 6.536850908261866 0.07318820867114273 YHGHS(ph)MSDPGVSYR ddPTM_PC-9_AZD4547_30min_R2 2 YHGHSMSDPGVSYR 14 0 P08559-3;P08559;P08559-2;P08559-4;Q5JPU3;P29803 P08559-3 PDHA1;PDHA2 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial 1 YHGHS(0.999)MS(0.001)DPGVSYR;YHGHS(0.935)MS(0.065)DPGVSYR 135.61 2.4076999999999997e-05 56054000.0 46067.0 33770.0 71648.0 116576.0 82681.0 86036.0 56719.0 93975.0 71960.0 81838.0 True False 60715.3477468747 44685.49209165705 70697.90070602839 89701.20428124588 71202.17032794602 80656.15531917303 61766.88112073764 79453.32308066853 75763.65869074845 78972.8765295486 0.7688126660063771 0.5658334108538831 0.8952174950797945 1.1358482585813265 0.901602847166203 1.021314644515888 0.7821277865904614 1.0060836906572623 0.9593630372878796 1.0 16.269069619986603 -5.408521962838619 5.371401568632806 0.9672445199819836 0.6713512345691837 0.6052305103523423 0.09688667097423873 0.13841319367538252 5.555150874631619 0.024790992101126796 0.05276073050077605 3.903714404153726e-06 5.408521962838619 -0.2958932854127999 YHGHS(ph)MSDPGVSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YHGHSMSDPGVSYR 14 0 P08559-3;P08559;P08559-2;P08559-4;Q5JPU3;P29803 P08559-3 PDHA1;PDHA2 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial 1 Y(0.001)HGHS(0.928)MS(0.071)DPGVSYR;YHGHS(0.981)MS(0.019)DPGVSYR 109.67 0.00032196 15022300.0 29200.0 33438.0 52334.0 46107.0 60671.0 48190.0 43255.0 51718.0 38394.0 36592.0 True False 34142.983273711376 36757.50365595662 53581.84103780022 43523.77427091087 48782.953080417705 45662.831566353445 39157.57326091916 50360.457299750524 38955.439615688185 43225.83993788735 0.789874374281045 0.8503595004463697 1.2395789443257494 1.006892505349847 1.1285599805698525 1.056378120863999 0.9058834557566952 1.1650544528947302 0.9012072332582676 1.0 15.39960637725047 -5.075644545067001 8.503276293494364 1.0525384105801479 0.8046317195470527 0.4564849955007573 0.10145109172868416 0.24570791167626715 25.636196778615396 0.024319598755862773 0.06513078958201447 8.401473365779933e-06 5.075644545067001 -0.24790669103309515 YHGHS(ph)MSDPGVSYR ddPTM_PC-9_Lapatinib_30min_R1 5 YHGHSMSDPGVSYR 14 0 P08559-3;P08559;P08559-2;P08559-4;Q5JPU3;P29803 P08559-3 PDHA1;PDHA2 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial 1 YHGHS(0.921)MS(0.079)DPGVSYR;YHGHS(0.971)MS(0.029)DPGVSYR;Y(0.002)HGHS(0.854)MS(0.143)DPGVSYR;YHGHS(0.995)MS(0.005)DPGVSYR;Y(0.004)HGHS(0.987)MS(0.009)DPGVSYR 141.1 7.3055e-05 127704300.0 225849.0 180969.0 240650.0 181529.0 174790.0 175981.0 122606.0 136200.0 246736.0 135934.0 True False 222628.35184436553 180549.97739920224 220864.68593586388 194879.24822299217 164509.19585036172 168454.70286174738 128953.93876423457 142528.34922254516 218945.99343473456 159430.0107793302 1.3964017863143048 1.132471712926775 1.385339465613952 1.2223498403492419 1.0318584000979698 1.0566059805070729 0.8088435679949989 0.8939869509249491 1.3733047646705705 1.0 17.282563699293704 -6.2101231043703224 3.1248899847326825 1.0093546078754885 1.2900706387969045 0.4068105874621566 0.15300629399797308 0.2625328208956621 5.1353207852439695 0.04832525000663638 0.06248297414326288 6.164202476668057e-07 6.2101231043703224 0.28071603092141606 YHGHSMS(ph)DPGVSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YHGHSMSDPGVSYR 14 0 P08559-3;P08559;P08559-2;P08559-4;Q5JPU3;P29803 P08559-3 PDHA1;PDHA2 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial 1 YHGHS(0.271)MS(0.729)DPGVSYR 67.846 0.018916 6474800.0 14630.0 10097.0 20889.0 21932.0 20918.0 22430.0 21610.0 20542.0 20475.0 21168.0 True False 17106.570044328684 11099.363431251682 21387.072981973644 20703.22114450336 16819.26806111943 21253.7313142417 19562.944357148615 20002.79426604811 20774.40814010563 25005.59083420421 0.6841098119916946 0.4438752719279594 0.855291647527043 0.8279436899440985 0.6726203021011199 0.849959173336929 0.7823428163268671 0.7999328789578944 0.8307905331190614 1.0 14.609963073117475 -3.2056238660574414 0.12078804795616445 1.0583589288746227 1.6640255207901228e-14 0.4826014215757256 0.10112993939238557 56.29976771420379 0.7069528199933988 0.829901007173645 9.68582942415537 0.0006228394807143698 3.2056238660574414 -1.058358928874606 YHGHSMSDPGVS(ph)YR ddPTM_PC-9_Lapatinib_30min_R1 1 YHGHSMSDPGVSYR 14 0 P08559-3;P08559;P08559-2;P08559-4;Q5JPU3;P29803 P08559-3 PDHA1;PDHA2 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial 1 YHGHSMS(0.015)DPGVS(0.984)Y(0.001)R 60.949 0.037364999999999995 1835400.0 9784.2 7798.0 12880.0 7803.9 11011.0 8148.1 5816.7 7106.8 10225.0 5561.7 True False 9644.675513797469 7779.944210107689 11821.056118237791 8377.82483904725 10363.354628458917 7799.624757148806 6117.860264668317 7437.007872648943 9073.352825976594 6523.032434500579 1.478557037795243 1.1926882609013645 1.8122025663579033 1.2843451145109444 1.588732653489 1.19570534647295 0.9378859182595366 1.1401151147607838 1.3909715944362422 1.0 12.671327086719527 -6.888265273209226 5.82256238888521 1.1209350705273324 1.4630735904739405 0.4425627030033463 0.191104779195987 0.20404808005500516 9.677177909588469 0.06638970673487997 0.05853047482411465 1.2934055697129514e-07 6.888265273209226 0.34213851994660804 YHPGYFGK ddPTM_PC-9_AZD4547_30min_R2 2 YHPGYFGK 8 0 E9PLL6;P46776 E9PLL6 RPL27A 60S ribosomal protein L27a 0 ; 81.78399999999999 0.014599 21293000.0 182325.0 196742.0 238120.0 281080.0 226376.0 227200.0 215212.0 263440.0 233126.0 232540.0 False True 240300.55740441 260335.00400049755 234962.37321515565 216281.34864271007 194947.5999341945 212993.14808354748 234365.45107911236 222731.40124896343 245448.5644238385 224398.84537966782 1.0708636089363006 1.1601441333623093 1.0470747869384758 0.9638255859863116 0.8687549154023329 0.9491722104147966 1.0444146924311564 0.9925692838219234 1.093804934729303 1.0 17.77570572716911 -5.524944668207712 4.371156489943093 0.9836509517047044 1.1146734049388827 0.42713536294769683 0.05920831665918025 0.1868484365519562 8.81853492007296 0.01740127275637534 0.03414582183139462 2.9857629992847255e-06 5.524944668207712 0.13102245323417827 YHPGYFGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YHPGYFGK 8 0 E9PLL6;P46776 E9PLL6 RPL27A 60S ribosomal protein L27a 0 66.79899999999999 0.040342 7360200.0 132860.0 143310.0 127280.0 144670.0 162480.0 129060.0 147410.0 130820.0 122770.0 114880.0 False True 155350.5738953872 157536.86969720482 130314.83791208791 136564.60892646824 130643.21037243937 122291.8664028548 133446.25764402002 127386.11361524742 124565.27899197901 135706.83461042048 1.1447512893610616 1.1608617218834465 0.9602673165739102 1.006320789358253 0.9626870359734093 0.9011474385496012 0.983342202528782 0.9386860579346669 0.9178998194864244 1.0 17.050133855549213 -5.263437803156063 24.617440980828416 0.9572584047438173 1.1528065234393445 0.856037974412394 0.03181995291643813 44.582190488511294 549193.5596689929 0.008441379722610158 0.0191151635875358 5.4520797125383106e-06 5.263437803156063 0.19554811869552724 YHPGYFGK ddPTM_PC-9_Lapatinib_30min_R1 2 YHPGYFGK 8 0 E9PLL6;P46776 E9PLL6 RPL27A 60S ribosomal protein L27a 0 ; 73.616 0.024730000000000002 25648000.0 174452.0 204817.0 212840.0 207752.0 205131.0 196922.0 203467.0 183482.0 199254.0 201411.0 False True 171964.28248942122 204342.75882041926 195341.11678615888 223030.77512035603 193065.597883063 188500.10510760272 214001.52568832316 192007.24355397228 176811.91628236108 236224.6229867121 0.7279693383153136 0.8650358131036737 0.8269295313772055 0.944147025405145 0.8172966706096644 0.7979697574465219 0.9059238744149081 0.8128163826713903 0.7484906274664981 1.0 17.84979982701843 -11.731923755308369 2.4731122604231053 1.5504558933563244 0.8326428280372937 0.40669335187111333 0.06225286636960064 11335831.848003581 1097992.6117314678 35479505.29034897 0.015310722916683894 1.853857057789191e-12 11.731923755308369 -0.7178130653190307 YHS(ph)VSTETPHER ddPTM_PC-9_AZD4547_30min_R2 2 YHSVSTETPHER 12 0 C9JIE2;Q86TI0-2;Q86TI0;H7C380;H7C0Z7;H0Y8P0;H0YA01 C9JIE2 TBC1D1 TBC1 domain family member 1 1 YHS(0.678)VS(0.322)TETPHER;YHS(0.949)VS(0.051)TETPHER 148.85 8.7388e-05 24809000.0 27415.0 29349.0 42847.0 79769.0 53006.0 45054.0 40865.0 56102.0 46491.0 50053.0 True False 36132.399732575825 38835.4902990241 42278.82078426755 61379.48946876464 45647.03185016043 42236.76625772953 44501.90583400524 47432.72499570814 48948.41934674236 48300.65970494751 0.7480725926580818 0.8040364362776213 0.875325948807628 1.2707795264849653 0.945060215098568 0.8744552665686086 0.9213519257470275 0.9820305827178906 1.0134109895341348 1.0 15.559755273508149 -5.5292720385487675 24.999987289290825 0.9957795753072569 0.7919611216539496 0.45150967147626897 0.1005217485464252 150.78843935704185 589633.1370430349 0.028957932334868704 0.05031937232642889 2.956160171673188e-06 5.5292720385487675 -0.2038184536533073 YHS(ph)VSTETPHER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YHSVSTETPHER 12 0 C9JIE2;Q86TI0-2;Q86TI0;H7C380;H7C0Z7;H0Y8P0;H0YA01 C9JIE2 TBC1D1 TBC1 domain family member 1 1 YHS(0.958)VS(0.04)T(0.002)ETPHER 92.265 0.0033748000000000003 8080100.0 7832.8 10211.0 11764.0 12211.0 14673.0 13125.0 10268.0 12496.0 10778.0 11319.0 True False 9158.73833514817 11224.680597851931 12044.498375218447 11526.85725859615 11797.930981011827 12436.701894758018 9295.340706117624 12167.993240606425 10935.607860027272 13371.045098845298 0.684968023624354 0.839476683750119 0.9007896006766585 0.8620760137583854 0.8823492026087533 0.9301219016778302 0.6951843058939615 0.9100255926634512 0.8178573760828654 1.0 13.706824612370063 YHS(ph)VSTETPHER ddPTM_PC-9_Lapatinib_30min_R1 1 YHSVSTETPHER 12 0 C9JIE2;Q86TI0-2;Q86TI0;H7C380;H7C0Z7;H0Y8P0;H0YA01 C9JIE2 TBC1D1 TBC1 domain family member 1 1 Y(0.012)HS(0.97)VS(0.018)TETPHER 92.26899999999999 0.0033734999999999998 7945800.0 9252.4 8596.8 9081.4 7331.1 14794.0 16479.0 13057.0 12887.0 19531.0 14060.0 True False 9120.45907931765 8576.894637785814 8334.76234721775 7870.253549832681 13923.84600612308 15774.231584425224 13733.027571608336 13485.777066306486 17331.213109452226 16490.252266227628 0.5530818408397873 0.5201190678781469 0.5054357090878174 0.4772670194955792 0.8443682838399871 0.9565791553553836 0.8327966940647631 0.8178029570794154 1.0509974516852543 1.0 14.009325848697891 -6.332405157250259 4.345670907728604 0.9120607851093913 0.5131305749394326 0.8898021090851563 0.06975975519814469 0.07057404953107946 2.5821383212103766 0.02201304499534536 0.02544864506053839 4.651519465864841e-07 6.332405157250259 -0.39893021016995867 YHSDDYIK ddPTM_PC-9_AZD4547_30min_R2 2 YHSDDYIK 8 0 Q13547;Q5TEE2 Q13547 HDAC1 Histone deacetylase 1 0 ; 98.58200000000001 0.0045843 4019500.0 29050.0 24855.0 39135.0 55741.0 46537.0 39475.0 23110.0 37776.0 31489.0 40195.0 False True 38287.295722463175 32888.89268398388 38616.044329645265 42890.77363986521 40076.140837092316 37006.622009674444 25166.74522999784 31938.587206122258 33153.44425393237 38787.7852844058 0.9870967223760558 0.8479188085329146 0.9955722928364878 1.1057804235373287 1.033215496663185 0.9540792736251571 0.6488317145582388 0.823418686370908 0.8547392951373625 1.0 15.243314782373606 -7.023387659030926 24.027569383207428 0.8148070147166232 0.9922658945495597 0.370412076178254 0.09947318333398472 474.8408570261368 487831.51963823417 0.0385432518949371 0.03007982331180521 9.47572265720128e-08 7.023387659030926 0.1774588798329365 YHSDDYIK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YHSDDYIK 8 0 Q13547;Q5TEE2 Q13547 HDAC1 Histone deacetylase 1 0 77.318 0.019271 0.0 15812.0 12604.0 16671.0 19453.0 22681.0 20291.0 17832.0 25780.0 17295.0 16731.0 False True 18488.659298764553 13855.241823065888 17068.499865119564 18363.111477476938 18236.820866920818 19226.90423973598 16142.823867499965 25103.30231616786 17547.90665607457 19764.197857476873 0.9354621640650203 0.7010272778575932 0.8636070124476357 0.9291098788777862 0.9227200111246487 0.9728148027248356 0.8167710110933276 1.2701402048892758 0.8878633366562928 1.0 14.270601783200592 -6.498889767596274 0.6709995198319504 1.0293793787418934 0.8115418650913039 0.22905846299847665 0.12227844653575709 1.0414830030970992 1.0395230980339962 0.08292781152721668 0.11578607701569782 3.1703720631464396e-07 6.498889767596274 -0.21783751365058956 YHSDDYIK ddPTM_PC-9_Lapatinib_30min_R1 2 YHSDDYIK 8 0 Q13547;Q5TEE2 Q13547 HDAC1 Histone deacetylase 1 0 ; 88.177 0.0093758 4924800.0 55385.0 45186.0 52963.0 45068.0 49542.0 48493.0 38847.0 39456.0 46092.0 41626.0 False True 54595.19974363491 45081.37459321954 48608.58658309222 48382.451062440734 46628.03696331953 46419.06743270422 40858.30758016916 41289.26980120963 40900.633589722594 48820.99863684148 1.1182729003506306 0.923401320168819 0.9956491661440745 0.991017234660378 0.9550815891777541 0.9508012684868615 0.8369002830953259 0.8457276777220973 0.8377672463024549 1.0 15.575214185395343 -6.910017658574875 1.8411040668794953 0.8680577611622657 0.9974208681526576 0.4119874242107706 0.0647817460656605 0.31784524564383665 2.200418278378782 0.027229060439108412 0.022328100715292676 1.2302187486443635e-07 6.910017658574875 0.12936310699039189 YHSDFNR ddPTM_PC-9_AZD4547_30min_R2 4 YHSDFNR 7 0 Q15424-2;Q15424;Q15424-4;Q15424-3;K7EII0 Q15424-2 SAFB Scaffold attachment factor B1 0 ;;; 168.74 0.00019517 16017500.0 4810.88 7031.56 8215.4 11908.9 10115.7 10748.7 8958.0 12075.499999999998 8911.3 7828.879999999999 False True 6340.639767479637 9304.374260349789 8106.458428153001 9163.48709567089 8711.309664692068 10076.582089813497 9755.244646054549 10209.50894238483 9382.333125220484 7554.793294125613 0.8392869957686246 1.2315855508031701 1.0730218700300307 1.212936838761181 1.1530837874102695 1.3337998403806433 1.291265593413382 1.351394875399628 1.2419046769308584 1.0 12.883176567170715 -4.143047315878259 1.0539741166278982 1.2392341428995242 2.0007444291637778e-67 0.47132020006377184 0.11101816424277522 5.106198006758676 1.7870240335557162 0.03400739612563157 9.830675751222058 7.193705991447475e-05 4.143047315878259 -1.2392341428995242 YHSDFNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YHSDFNR 7 0 Q15424-2;Q15424;Q15424-4;Q15424-3;K7EII0 Q15424-2 SAFB Scaffold attachment factor B1 0 ;;; 153.15 0.00043218 11956500.0 7262.09 7996.820000000001 9028.82 11576.33 12206.8 10425.32 10560.95 9548.32 8261.09 6882.96 False True 8491.418404184476 8790.691440457776 9244.101310790533 10927.745761068238 9814.965167247 9878.597866473041 9560.540361343297 9297.686717281296 8381.892812803184 8130.786162518619 1.0443539203291687 1.0811613126638597 1.1369258920378555 1.3439962068419744 1.2071360593016365 1.2149622027955307 1.1758445210889414 1.1435163256588727 1.0308834404527965 1.0 12.989179137323134 -8.253842543860312 2.4725259034236107 0.9999153698544085 1.176643780392494 0.39645711892950863 0.07656084120822658 0.3215199640796516 3.583684332577506 0.07834628511846407 0.022651566499048724 5.573877966821099e-09 8.253842543860312 0.17672841053808552 YHSDFNR ddPTM_PC-9_Lapatinib_30min_R1 4 YHSDFNR 7 0 Q15424-2;Q15424;Q15424-4;Q15424-3;K7EII0 Q15424-2 SAFB Scaffold attachment factor B1 0 ;;; 153.15 0.00043218 15019700.0 5648.389999999999 5759.199999999999 11008.6 7897.3 8077.5 7497.51 9123.17 6944.0 8428.59 7349.1 False True 5567.842922812133 5745.864926244192 10103.51540242489 8478.093786620519 7602.39733097601 7176.858974849448 9595.523102586358 7266.6435903183165 7479.273437212527 8619.382142939785 0.6459677538920587 0.6666214388638846 1.1721855737305686 0.9836080644788447 0.8820118663845533 0.8326419290654237 1.113249528035619 0.8430585243596017 0.867727328151806 1.0 13.073368741996873 -5.160320842921547 9.016998162591499 0.9547877381037342 0.6526957457697917 0.5630572096572075 0.10754234969274189 0.2619967207358298 21.49285146696521 0.027828236406932456 0.07409467153183139 6.913200569941171e-06 5.160320842921547 -0.30209199233394246 YHSDFNRQDR ddPTM_PC-9_Lapatinib_30min_R1 1 YHSDFNRQDR 10 1 Q15424-2;Q15424;Q15424-4;Q15424-3;K7EII0 Q15424-2 SAFB Scaffold attachment factor B1 0 68.846 0.017988999999999998 2572200.0 2844.6 654.98 955.55 656.08 904.47 885.23 768.1 0.0 479.61 0.0 False True 2804.0354823642497 653.4634340518517 876.9883675296683 704.3303118187212 851.2708528564381 847.3707764719187 807.8684596578363 0.0 425.59127128280056 0.0 0.0 YHT(ph)LSLGR ddPTM_PC-9_AZD4547_30min_R2 1 YHTLSLGR 8 0 V9GZ20;V9GXZ5;Q70EL4-2;Q70EL4-3;Q70EL4-4;Q70EL4 V9GZ20 USP43 Ubiquitin carboxyl-terminal hydrolase 43 1 YHT(0.743)LS(0.257)LGR 99.01299999999999 0.011177 2925700.0 7072.6 9045.4 10863.0 13704.0 10202.0 10429.0 10660.0 10901.0 10456.0 10271.0 True False 9321.539680781163 11969.148657562175 10718.949522241894 10544.75452468942 8785.628399338499 9776.872981352622 11608.719348843657 9216.500930059794 11008.682813652928 9911.41541624909 0.9404852172273128 1.2076124503811605 1.081475154867276 1.0638999660333088 0.8864151113003557 0.9864255074329853 1.171247381056388 0.9298874623850362 1.1107074369625294 1.0 13.274875383263538 -6.014121335800077 24.388196838078002 1.013269281211011 1.0868088664295856 0.0801224052760483 0.09717253164693143 1106.792269455113 1911488.8068103264 0.027789548177699692 0.03748703998657826 9.680073707664292e-07 6.014121335800077 0.07353958521857473 YHT(ph)LSLGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YHTLSLGR 8 0 V9GZ20;V9GXZ5;Q70EL4-2;Q70EL4-3;Q70EL4-4;Q70EL4 V9GZ20 USP43 Ubiquitin carboxyl-terminal hydrolase 43 1 YHT(0.715)LS(0.285)LGR 81.525 0.037245 2920500.0 9193.1 7860.2 11043.0 9601.2 8485.0 8272.7 8356.0 7659.2 7767.5 6559.6 True False 10749.310257998504 8640.508709747899 11306.307000810717 9063.27589151038 6822.425160082151 7838.865048743975 7564.459187798878 7458.154115593203 7881.084992833725 7748.803554234974 1.387221934684827 1.1150764952643015 1.4591035792398492 1.169635522190649 0.8804488476615816 1.0116226323042838 0.9762099574281572 0.9624910559923897 1.0170712081772229 1.0 12.919757854452337 -6.0399455337513395 5.334417596626166 0.9769732888359722 1.3032369049408368 0.752610925866976 0.08947445304210654 0.091549775974676 6.630641022118831 0.02481384310325327 0.03345733584964127 9.121252247009525e-07 6.0399455337513395 0.32626361610486454 YHT(ph)LSLGR ddPTM_PC-9_Lapatinib_30min_R1 1 YHTLSLGR 8 0 V9GZ20;V9GXZ5;Q70EL4-2;Q70EL4-3;Q70EL4-4;Q70EL4 V9GZ20 USP43 Ubiquitin carboxyl-terminal hydrolase 43 1 Y(0.001)HT(0.643)LS(0.356)LGR 114.86 0.0093244 0.0 12313.0 13322.0 13184.0 12564.0 12690.0 10665.0 11988.0 11251.0 9418.8 8865.2 True False 12137.414362072339 13291.153727501247 12100.062411711728 13487.998472275356 11943.599149499916 10208.882811329273 12608.679982265514 11773.762533794847 8357.955559638964 10397.538007863524 1.1673354166046779 1.2782981622620007 1.1637430324910192 1.2972300233069172 1.1486949257090597 0.981855781975351 1.2126601482706514 1.1323606150696925 0.80383986606425 1.0 13.343954338268366 -7.533936141290559 0.6521740183694484 0.9406767111267146 1.2249473498724621 0.4673945663418315 0.10413544806969667 0.6887545063055641 0.5779841389010066 0.09659087762754473 0.05654251631697433 2.9245823771504928e-08 7.533936141290559 0.28427063874574754 YHTINGHNAEVR ddPTM_PC-9_AZD4547_30min_R2 4 YHTINGHNAEVR 12 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;;; 167.84 4.4374e-05 118247300.0 15567.6 15083.9 29090.3 44637.200000000004 32657.1 29807.5 20033.399999999998 30824.7 26742.4 35814.1 False True 20517.772973804385 19959.475693258682 28704.543614735638 34346.783177865305 28123.22536757865 27943.63231294166 21816.333790161785 26061.45089613926 28155.948668308345 34560.25925996365 0.5936811069462437 0.5775267929306522 0.8305650544696125 0.9938230763695212 0.8137446295189693 0.8085481102079861 0.6312549227729587 0.754087250911632 0.8146914771824533 1.0 15.076826419726205 -14.522878743192475 0.030392312564110992 2.1014686910126184 8.616517269476331e-09 0.2983068936254849 0.11796270169100777 2412.692007771189 5.498357980534847 298.55698159056215 119.2283800482696 3.0000000144224432e-15 14.522878743192475 -2.101468682396101 YHTINGHNAEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 YHTINGHNAEVR 12 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;;;; 174.23 3.3948e-05 61263100.0 19882.199999999997 20579.1 29256.0 33296.0 35569.1 31703.9 31370.0 29815.4 27498.7 22144.3 False True 23247.863768650168 22622.05704546615 29953.573993997867 31430.533067088465 28599.590189920782 30041.291672473795 28398.406500867753 29032.777342027577 27900.81646507071 26158.88629581766 0.8887176428595542 0.8647943490271225 1.1450630449350172 1.201524128804889 1.0933030506919306 1.1484163099587639 1.085612215280287 1.1098628975909193 1.0665903796344554 1.0 14.675013499525221 -5.258623178395932 24.995751058829914 1.1139226700014297 0.8767559705743457 0.7592651359544429 0.05155731770587965 102.66224673212949 911186.4541926616 0.013024257543594231 0.031454466938034026 5.512858197040226e-06 5.258623178395932 -0.23716669942708402 YHTINGHNAEVR ddPTM_PC-9_Lapatinib_30min_R1 4 YHTINGHNAEVR 12 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 ;;; 147.58 2.4539e-05 117187000.0 21174.4 18542.5 28225.8 22893.6 25402.1 21982.6 16428.8 22937.5 23298.699999999997 19365.3 False True 20872.4491730906 18499.5659804978 25905.183678738824 24577.27171481082 23907.99842045013 21042.455441943457 17279.402877264227 24003.259987460613 20674.555059812326 22712.566302359737 0.918982421238856 0.814507957146867 1.1405661224661956 1.0821001637431586 1.052633071145562 0.9264675405595728 0.7607860180674066 1.056827294103123 0.9102694422366675 1.0 14.471203105519946 -6.8171568167648875 12.201607231256379 0.9237294508023408 1.0035165669340316 0.09256202628622978 0.10977787124440869 2.1067781264018386 456.4663870955956 0.04113645135964205 0.03629271061764922 1.5235025421585886e-07 6.8171568167648875 0.07978711613169076 YHTLS(ph)LGR ddPTM_PC-9_AZD4547_30min_R2 1 YHTLSLGR 8 0 V9GZ20;V9GXZ5;Q70EL4-2;Q70EL4-3;Q70EL4-4;Q70EL4 V9GZ20 USP43 Ubiquitin carboxyl-terminal hydrolase 43 1 YHT(0.225)LS(0.775)LGR 153.1 5.7341000000000005e-05 2146200.0 9465.4 8592.8 12344.0 14189.0 13127.0 13949.0 9646.3 11729.0 10531.0 12659.0 True False 12475.200307449326 11370.254558637565 12180.310494573674 10917.945267864725 11304.542638513667 13076.766824900553 10504.802012640766 9916.55255560694 11087.647160537392 12215.812263099717 1.0212337942629606 0.930781704380287 0.9970937856802791 0.8937551619751511 0.92540245339733 1.0704786995132136 0.8599347948701376 0.8117800390205614 0.9076471479534626 1.0 13.576462175122305 -7.333848752581315 24.999998315195672 0.8791553464143094 0.9665143881737716 0.2370663024136963 0.06582017152051366 192.41879982152383 66433.10838162931 0.026818558454290268 0.018081069530374458 4.636083478923348e-08 7.333848752581315 0.08735904175946219 YHTLS(ph)LGR ddPTM_PC-9_Lapatinib_30min_R1 1 YHTLSLGR 8 0 V9GZ20;V9GXZ5;Q70EL4-2;Q70EL4-3;Q70EL4-4;Q70EL4 V9GZ20 USP43 Ubiquitin carboxyl-terminal hydrolase 43 1 YHT(0.347)LS(0.653)LGR 120.27 0.0019399 3256000.0 9286.6 11399.0 11410.0 9249.2 11020.0 12438.0 10431.0 10640.0 12121.0 7395.2 True False 9154.171381046137 11372.606315852476 10471.913843873697 9929.417022426704 10371.825266153595 11906.055734394138 10971.066140725015 11134.373243229687 10755.80534021148 8673.450466515398 1.0554244145840923 1.3111974709208754 1.207352700554574 1.1448058717531244 1.1958130511259526 1.372701185111795 1.2649021497361126 1.2837305390991616 1.240083791535467 1.0 13.082390324318261 -4.745589504559808 24.639502184355436 1.2353457998030508 1.0554238125577462 0.20828511746475342 0.09684455475421955 1123.066141131344 1745753.4019958642 0.02326707688115569 0.5681672555832624 1.7964308122434586e-05 4.745589504559808 -0.17992198724530462 YHTSQSGDEMTSLSEYVS(ph)RMK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YHTSQSGDEMTSLSEYVSRMK 21 1 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 1 YHTSQSGDEMT(0.009)S(0.003)LS(0.011)EY(0.128)VS(0.847)RMK 47.082 0.029896 19331000.0 7245.0 2114.9 4321.3 8053.0 10713.0 8897.4 7464.5 8407.5 6983.7 7436.4 True False 8471.435404727365 2324.8532951128254 4424.336180621513 7601.816518178261 8613.864553913976 8430.804681022475 6757.408521699946 8186.812033482595 7085.82340063764 8784.560453489989 0.9643550692808741 0.2646522051298756 0.503649124397998 0.865361056870883 0.9805686464929276 0.9597298266270146 0.7692369535706612 0.9319546580421203 0.8066224187486281 1.0 13.100754385644201 -5.795270942226739 6.712182763142983 0.9006759687819406 0.5460033162786772 0.41818953542000725 0.17427367317371575 0.15318581701549194 20.614510381792453 0.047307485345306495 0.07224705790695621 1.6022454898796548e-06 5.795270942226739 -0.3546726525032634 YHTVNGHNCEVR ddPTM_PC-9_AZD4547_30min_R2 3 YHTVNGHNCEVR 12 0 F8VZ49;F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;A0A2R8Y4L2;H0YH80 F8VZ49;F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 0 ;; 167.84 0.00025545 52562000.0 8638.4 9071.7 19082.5 20319.7 18192.3 14890.599999999999 11766.599999999999 16118.3 12525.8 19448.7 False True 11385.231510117923 12003.949618237652 18829.453581716 15635.307101235514 15666.613166956062 13959.488428049619 12813.804605075393 13627.587096686791 13187.888216072484 18767.806932723568 0.6066362229177998 0.6396032131653887 1.0032847017881958 0.8330918554993112 0.8347599281639955 0.7437996606683885 0.682754498221805 0.7261150514568495 0.7026866944735066 1.0 14.195972456882146 -11.476001959914253 2.3795939719498334 1.186922968686543 0.7582824801118482 0.3161282415304105 0.10890020900967398 35163136.25602024 15802458.911757633 36337124.198455974 0.029318220652510676 3.3419353185096674e-12 11.476001959914253 -0.42864048857469483 YHTVNGHNCEVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 YHTVNGHNCEVR 12 0 F8VZ49;F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;A0A2R8Y4L2;H0YH80 F8VZ49;F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 0 ;;;;; 140.63 2.7881e-05 66808700.0 16497.6 23236.899999999998 25472.600000000002 25475.8 31908.699999999997 27504.499999999996 25471.2 19699.9 27140.800000000003 21747.8 False True 19290.317837547293 25543.705864677864 26079.963389373454 24048.473519657982 25656.419293519542 26062.115601094993 23058.38354048144 19182.798498769396 27537.682854650986 25690.50398450993 0.7508734686239855 0.9942858995712743 1.0151596638625053 0.9360841474405481 0.9986732572077629 1.0144649406959523 0.8975450055158309 0.7466882903634607 1.0719012313364817 1.0 14.64894757219461 -4.755137424622704 24.97929959406914 0.9572819601573693 0.7508731223490174 0.35638297762299553 0.08545888927412557 251.83589440076935 998116.0362135434 0.02168216652265419 0.19761049545940013 1.7573674388715945e-05 4.755137424622704 -0.20640883780835195 YHTVNGHNCEVR ddPTM_PC-9_Lapatinib_30min_R1 3 YHTVNGHNCEVR 12 0 F8VZ49;F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;A0A2R8Y4L2;H0YH80 F8VZ49;F8W6I7 HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 0 ;; 128.08 9.054799999999999e-05 61497000.0 13296.6 9922.2 11748.5 11753.499999999998 14564.4 14766.599999999999 9344.599999999999 11547.6 16585.7 11239.199999999999 False True 13106.988045702197 9899.225755518157 10782.583680521482 12617.891598526603 13707.750626712108 14135.066940625866 9828.417664521035 12084.143652586374 14717.643810836196 13181.880744707363 0.9943185118682525 0.7509721827435573 0.8179852245174332 0.9572148195615253 1.0398933879155208 1.0723103337360425 0.7456005599555456 0.9167237882529213 1.1165056106842306 1.0 13.686268603270852 -5.813377499198698 6.609820931578186 0.9723316362531189 0.8442233577992804 0.205622720514958 0.11075710405978015 0.3194228311251691 30.515895038202196 0.03238007863388555 0.04892724315485655 1.5368182202399702e-06 5.813377499198698 -0.12810827845383854 YHYLGGR ddPTM_PC-9_Lapatinib_30min_R1 2 YHYLGGR 7 0 Q8NCW5-2;Q8NCW5 Q8NCW5-2 APOA1BP NAD(P)H-hydrate epimerase 0 ; 117.56 0.00029129 0.0 14731.7 13864.4 13752.3 11454.2 14013.3 13790.4 12092.3 12398.400000000001 13441.9 10550.5 False True 14521.623256537097 13832.297833626193 12621.638979413168 12296.580078091078 13189.065245207823 13200.61673899251 12718.380125921683 12974.474926584484 11927.931672517836 12374.139867342428 1.1735460736840597 1.11783913725851 1.0200013184531667 0.9937321066285952 1.0658571332312259 1.066790652159291 1.0278193282336954 1.0485152960672803 0.9639402657794247 1.0 13.595040625772267 -5.0845095801028455 2.967670286574304 1.0271449785285205 1.16904958863311 0.7230498976557551 0.031052668064276954 0.1458571848855511 2.3682668449818594 0.008404907149922211 0.034259824223034516 8.231716783754167e-06 5.0845095801028455 0.14190461010458955 YIASVQGSTPS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 YIASVQGSTPSPR 13 0 P49792;F8WBP7 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 YIASVQGSTPS(1)PR 77.533 0.016012000000000002 8699800.0 32335.0 22290.0 29017.0 34979.0 31152.0 33937.0 23374.0 31876.0 20058.0 25538.0 True False 42616.85739021846 29494.806595292746 28632.21562062902 26915.13197016282 26827.082522661538 31814.914025137983 25454.240718562083 26950.29663760994 21118.224930781405 24643.922393162233 1.72930496656827 1.1968389660030927 1.161836787335988 1.092161042417126 1.0885881758053682 1.2909841833443458 1.0328810614021688 1.0935879527476373 0.8569344032929159 1.0 14.588944277092141 -2.2879270849338793 1.110773263999649 1.0768764594513898 199.999382650786 0.7786622092790223 0.10414434171225537 222.17386124951986 1.2103528383953663 0.03208368376289784 111494.89753044906 0.005153151552009976 2.2879270849338793 198.9225061913346 YIASVQGSTPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YIASVQGSTPSPR 13 0 P49792;F8WBP7 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 YIASVQGS(0.001)T(0.005)PS(0.994)PR;YIASVQGSTPS(1)PR 122.1 0.00018711 11783900.0 29350.0 23180.0 19986.9 26319.0 27418.0 26505.0 23914.0 27012.0 22330.0 14245.9 True False 34318.375311076365 25481.157208716853 20463.463496740347 24844.431757349263 22045.63972175985 25115.03114061419 21648.69279763313 26302.963621579762 22656.534005790414 16828.568899517653 2.0392925575543153 1.5141606728928212 1.2159954669304576 1.476324689621193 1.3100127440065168 1.4924044516544746 1.286425062457547 1.5629946776005217 1.3463137680376258 1.0 14.038624874734548 -4.791213944251949 3.3167491270118665 1.3637862871831434 2.12292679550438 0.6536579818128341 0.15283617127719784 0.17794413618797275 3.1101378500374457 0.03546737432654927 0.3446964958265283 1.617283127519869e-05 4.791213944251949 0.7591405083212364 YIASVQGSTPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 YIASVQGSTPSPR 13 0 P49792;F8WBP7 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 YIASVQGST(0.001)PS(0.999)PR 108.23 0.00092009 7995300.0 29024.0 22795.0 23520.0 22323.0 29124.0 28499.0 22023.0 17163.0 26243.0 21366.0 True False 28610.11243765027 22742.219578020635 21586.276389825536 23964.707887345012 27410.98357998705 27280.16420441377 23163.243180633413 17960.45563661195 23287.236988958815 25059.08463159457 1.1417062058834564 0.9075439072242557 0.8614151996042781 0.9563281436517531 1.0938541444337992 1.0886337073150252 0.924345143534458 0.7167243297453632 0.929293201699722 1.0 14.613046095822213 -7.520806779074964 24.989441620362 0.8579122045894229 0.9991901799802408 0.21839837364813752 0.10569227570141705 116.35341223311374 1403367.2832412473 0.050258466707064 0.02961241299297584 3.0143468317759776e-08 7.520806779074964 0.141277975390818 YIDENQDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YIDENQDR 8 0 J3KSS4;J3QRP4;J3QQN6;J3QR27;J3QLU1;J3QKQ0;J3QRD0;J3QRA8;J3QL02;J3KSV5;A0A087WYZ1;J3QKT2;Q96KP4-2;Q96KP4 J3KSS4 CNDP2 Cytosolic non-specific dipeptidase 0 101.43 0.02114 4878100.0 28084.0 19402.0 20557.0 32653.0 28773.0 27902.0 24135.0 20914.0 30751.0 19233.0 False True 32838.066515716135 21328.102336649023 21047.15684285665 30823.558272454346 23135.13719870874 26438.77000133625 21848.758077731698 20365.029660214692 31200.675199823585 22719.790651655767 1.4453507525309426 0.9387455484804249 0.9263798758340575 1.356683199464604 1.0182812664703274 1.1636889796521717 0.9616619454255143 0.8963563957280801 1.373281808719032 1.0 14.471661920940921 -7.233567147487628 24.268140678936113 1.0491880122016062 1.1267035779402361 0.03830914987250533 0.19531573174357714 2151.608086187925 1873391.025498486 0.07323883182426097 0.05671576710201939 5.84026902074887e-08 7.233567147487628 0.07751556573862994 YIDENQDR ddPTM_PC-9_Lapatinib_30min_R1 2 YIDENQDR 8 0 J3KSS4;J3QRP4;J3QQN6;J3QR27;J3QLU1;J3QKQ0;J3QRD0;J3QRA8;J3QL02;J3KSV5;A0A087WYZ1;J3QKT2;Q96KP4-2;Q96KP4 J3KSS4 CNDP2 Cytosolic non-specific dipeptidase 0 ; 117.81 0.016266 18249800.0 55844.0 48547.0 62620.0 47035.0 51597.0 46221.0 47639.0 42907.0 58485.0 37495.0 False True 55047.65431946465 48434.5924042188 57471.625320190244 50494.11080416036 48562.16590360498 44244.235576413535 50105.51432058279 44900.615859704536 51897.80342564709 43975.96079105296 1.2517669501530087 1.1013879295179143 1.3068873149414626 1.1482207527898638 1.1042889121705124 1.0061004871874262 1.1393841867072272 1.0210263755929057 1.1801402969279946 1.0 15.42442747773208 -6.15209416549179 3.1064279518921913 1.074954515625706 1.2097412911350154 0.43985143110276825 0.07275194631347384 0.2460225084956352 4.5327418793639795 0.021180504013157672 0.02836029931113913 7.045402911200764e-07 6.15209416549179 0.1347867755093093 YIDQEELNK ddPTM_PC-9_AZD4547_30min_R2 3 YIDQEELNK 9 0 P07900;P07900-2;Q14568;P08238;Q58FF8 P07900;P08238 HSP90AA1;HSP90AA2P;HSP90AB1;HSP90AB2P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 0 ;; 166.07 0.0010344000000000002 101951700.0 219555.0 189672.0 260208.0 304113.0 291573.0 272788.0 239005.0 295809.0 233210.0 267966.0 False True 289368.92297230294 250979.76476188295 256757.47190311304 234004.44634901316 251093.1218663327 255730.52323686075 260275.9819859647 250098.51606458586 245537.0044923486 258584.5919025021 1.1190493634725456 0.970590563479952 0.9929341497652807 0.9049435027329209 0.9710289388046986 0.988962727265987 1.00654095462927 0.9671825928394222 0.9495422858950814 1.0 17.98027678729529 -4.761234048852342 24.966847320415948 0.971461553187335 1.119049526914607 0.7143041935685936 0.027814981081925455 2.651025264101124 321576.02074671234 0.007119214818370022 0.04015969222646658 1.7328698723450993e-05 4.761234048852342 0.14758797372727206 YIDQEELNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 YIDQEELNK 9 0 P07900;P07900-2;Q14568;P08238;Q58FF8 P07900;P08238 HSP90AA1;HSP90AA2P;HSP90AB1;HSP90AB2P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 0 ;;;; 179.51 1.4932e-05 85401000.0 239697.0 260068.0 247444.0 286859.0 293545.0 261457.0 299560.0 261156.0 239962.0 215624.0 False True 280272.96786845144 285885.8323104655 253344.00339659545 270787.2202394265 236026.96448041426 247745.73465125685 271183.5081734128 254300.931717654 243470.99028649644 254714.92432135475 1.1003397960099583 1.1223756639787026 0.9946178225386209 1.06309915275241 0.9266318615183958 0.9726392566565696 1.064654962389565 0.9983746825797359 0.9558567914117483 1.0 17.95852396727865 -5.263699428935227 24.90014990919208 0.998322265310895 1.1113577373786019 0.5596393619800099 0.04056827627400168 129.15229457391473 1422957.3539619495 0.010813254404453965 0.024365001350491782 5.448796283656916e-06 5.263699428935227 0.11303547206770692 YIDQEELNK ddPTM_PC-9_Lapatinib_30min_R1 6 YIDQEELNK 9 0 P07900;P07900-2;Q14568;P08238;Q58FF8 P07900;P08238 HSP90AA1;HSP90AA2P;HSP90AB1;HSP90AB2P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2;Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 0 ;;;;; 171.56 0.00050281 239826900.0 593745.0 551436.0 539626.0 506008.0 602754.0 581130.0 622076.0 576358.0 634924.0 547975.0 False True 585278.0874205035 550159.1838221267 495260.0332965983 543221.516313206 567301.1947799586 556276.424580195 654284.0514387556 603137.6967783242 563412.1730738741 642691.7486192106 0.910666876738254 0.8560234124743547 0.7706027568591606 0.8452287079774852 0.8826956250780804 0.8655415691508809 1.0180371116393676 0.9384556407860126 0.8766444789190705 1.0 19.293767424479675 -7.112120163661524 6.6467819284942395 0.9529138021868375 0.8506643725870274 0.5193321059888765 0.048583030478185935 0.2190888285962824 11.466150269744947 0.019436489436473154 0.015046428793848703 7.724668239534147e-08 7.112120163661524 -0.1022494295998101 YIEIDS(ph)DEEPR ddPTM_PC-9_AZD4547_30min_R2 1 YIEIDSDEEPR 11 0 E7EW05;Q9NVU7-2;Q9NVU7 E7EW05 SDAD1 Protein SDA1 homolog 1 YIEIDS(1)DEEPR 113.07 0.0028263000000000003 0.0 2735.1 2719.9 4811.4 6144.0 3577.6 3998.6 4489.0 5348.3 4140.1 5140.0 True False 3604.80490638585 3599.054484456562 4747.5976922870905 4727.5957238537485 3080.9119938711433 3748.5669098894077 4888.512303654705 4521.843126707528 4358.937233818336 4960.050164494239 0.7267678323478046 0.7256084848132875 0.9571672734828456 0.9531346593418591 0.621145329522145 0.7557518141092506 0.9855771900551275 0.9116527004255827 0.8788091025814864 1.0 12.276138996343006 -7.258910015761733 24.9669494060473 0.9366474747622745 0.7943537223757938 0.3550747789640486 0.10143093026490875 301.1406883039359 2972530.5729214433 0.04348721898796395 0.03208446286662726 5.509218335822604e-08 7.258910015761733 -0.14229375238648068 YIEIDS(ph)DEEPR ddPTM_PC-9_Lapatinib_30min_R1 4 YIEIDSDEEPR 11 0 E7EW05;Q9NVU7-2;Q9NVU7 E7EW05 SDAD1 Protein SDA1 homolog 1 YIEIDS(1)DEEPR;YIEIDS(1)DEEPR;YIEIDS(1)DEEPR;YIEIDS(1)DEEPR 117.95 0.0019686 0.0 28809.700000000004 35554.7 28465.6 23598.300000000003 25190.800000000003 28652.0 27804.800000000003 25201.0 29006.699999999997 24176.3 True False 28398.868394948084 35472.37527662425 26125.26824839359 25333.797703621105 23709.126671018326 27426.620751074213 29244.39649406874 26371.93046077363 25739.659991907614 28355.141242105197 1.0015421243177571 1.2510033003803382 0.9213591293842537 0.8934463590681174 0.8361491296616115 0.9672538929323969 1.0313613409423992 0.9300581589631918 0.9077598934222978 1.0 14.791322722195465 -5.284816055187492 24.91858589241509 0.9328725784683125 1.1262727153209096 0.4987656217301899 0.07627885016581865 509.17519346459954 542759.3028868091 0.019795525606560428 0.04124722030476425 5.1901982249164365e-06 5.284816055187492 0.19340013685259705 YIEIDS(ph)DEEPRGELLSLR ddPTM_PC-9_AZD4547_30min_R2 7 YIEIDSDEEPRGELLSLR 18 1 E7EW05;Q9NVU7-2;Q9NVU7 E7EW05 SDAD1 Protein SDA1 homolog 1 Y(0.144)IEIDS(0.854)DEEPRGELLS(0.002)LR;Y(0.005)IEIDS(0.995)DEEPRGELLSLR;YIEIDS(1)DEEPRGELLSLR;YIEIDS(1)DEEPRGELLSLR;Y(0.001)IEIDS(0.999)DEEPRGELLSLR;Y(0.002)IEIDS(0.998)DEEPRGELLSLR;YIEIDS(1)DEEPRGELLSLR 116.73 0.00026368 16577500.0 15654.400000000001 13903.61 23586.499999999996 28828.1 26303.800000000003 18620.5 17859.6 25513.300000000003 17324.6 19518.8 True False 20632.173568252216 18397.680032587636 23273.727598854668 22182.226934705122 22651.97140663792 17456.157191415914 19449.069801370384 21570.805722309364 18240.342987128115 18835.45275306033 1.0953903704226042 0.9767580463176514 1.2356340940662136 1.1776848279424033 1.2026242057259544 0.9267713083551807 1.032577770035836 1.1452236378445748 0.9684048069491973 1.0 14.20116309171686 -6.7512678525614644 24.996103581370015 1.0247958642001924 1.136352857485693 0.3442332294956606 0.0843044868753212 285.89178514170146 702565.7176994585 0.029616454203383272 0.029294979295846586 1.7730955810139882e-07 6.7512678525614644 0.1115569932855005 YIEIDS(ph)DEEPRGELLSLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 10 YIEIDSDEEPRGELLSLR 18 1 E7EW05;Q9NVU7-2;Q9NVU7 E7EW05 SDAD1 Protein SDA1 homolog 1 Y(0.002)IEIDS(0.998)DEEPRGELLSLR;Y(0.003)IEIDS(0.996)DEEPRGELLS(0.002)LR;Y(0.085)IEIDS(0.915)DEEPRGELLSLR;Y(0.008)IEIDS(0.992)DEEPRGELLSLR;YIEIDS(1)DEEPRGELLSLR;Y(0.051)IEIDS(0.949)DEEPRGELLSLR;Y(0.008)IEIDS(0.992)DEEPRGELLSLR;Y(0.002)IEIDS(0.996)DEEPRGELLS(0.003)LR;Y(0.008)IEIDS(0.992)DEEPRGELLSLR;Y(0.005)IEIDS(0.995)DEEPRGELLSLR 100.46 0.00083117 18054600.0 19910.399999999998 20058.23 22683.030000000006 28229.84 30143.2 28632.2 30211.6 29963.010000000002 23822.510000000002 17610.43 True False 23280.837471674782 22049.478514176037 23223.879461070326 26648.213587176124 24236.85634477173 27130.677027892598 27349.73853495746 29176.512735933306 24170.869140988885 20803.06155491282 1.1191063108774397 1.059915073364231 1.1163683479841364 1.280975567794872 1.1650619924761985 1.3041675118961256 1.3146977651709437 1.4025105227380834 1.161889997642233 1.0 14.344508242774504 -5.688200925402244 5.210197395589054 1.2530479144893076 1.0900642876854576 0.23972608538107443 0.1056598105404208 0.2383679937816122 11.658150356553172 0.02806144052853948 0.048998993964545774 2.0502134325668496e-06 5.688200925402244 -0.16298362680385003 YIEIDS(ph)DEEPRGELLSLR ddPTM_PC-9_Lapatinib_30min_R1 15 YIEIDSDEEPRGELLSLR 18 1 E7EW05;Q9NVU7-2;Q9NVU7 E7EW05 SDAD1 Protein SDA1 homolog 1 Y(0.001)IEIDS(0.999)DEEPRGELLSLR;Y(0.031)IEIDS(0.969)DEEPRGELLSLR;Y(0.085)IEIDS(0.915)DEEPRGELLSLR;YIEIDS(0.999)DEEPRGELLSLR;Y(0.001)IEIDS(0.999)DEEPRGELLSLR;Y(0.046)IEIDS(0.954)DEEPRGELLSLR;Y(0.409)IEIDS(0.591)DEEPRGELLSLR;Y(0.005)IEIDS(0.995)DEEPRGELLSLR;YIEIDS(1)DEEPRGELLSLR;YIEIDS(1)DEEPRGELLSLR;Y(0.029)IEIDS(0.971)DEEPRGELLSLR;Y(0.003)IEIDS(0.997)DEEPRGELLSLR;Y(0.056)IEIDS(0.944)DEEPRGELLSLR;Y(0.001)IEIDS(0.999)DEEPRGELLSLR;Y(0.028)IEIDS(0.971)DEEPRGELLS(0.001)LR 95.988 0.00088857 30366100.0 48461.909999999996 42980.56 50875.05 41309.17 49596.32 50855.090000000004 42642.64000000001 38363.829999999994 50095.58999999999 43564.50000000001 True False 47770.83427657414 42881.041154037724 46692.299772372164 44347.18416515143 46679.16196771677 48680.13634970494 44850.46724716006 40146.35359584699 44453.297124250836 51094.56577895259 0.9349494128835988 0.8392485678330539 0.913840817717765 0.8679432634188153 0.9135836904782023 0.9527458665625411 0.877793294911126 0.7857264854648104 0.8700200588173411 1.0 15.640882239388404 -10.592193172413204 8.845176955864389 1.0000000006862722 0.8828951870779079 0.3628760047209406 0.046098067576134306 6.911712700512687e-10 0.0 0.046790980928166165 0.011348479636370394 2.5574480914068427e-11 10.592193172413204 -0.11710481360836422 YIES(ph)PDVEK ddPTM_PC-9_Lapatinib_30min_R1 1 YIESPDVEK 9 0 Q15545 Q15545 TAF7 Transcription initiation factor TFIID subunit 7 1 YIES(1)PDVEK 103.34 0.0028868 2713700.0 21774.0 24284.0 29196.0 22843.0 41045.0 31429.0 39526.0 33870.0 33164.0 31371.0 True False 21463.498767137444 24227.77189000451 26795.61757981914 24522.95042201416 38630.813797574796 30084.854934577364 41572.462877796665 35443.723848514026 29428.721087597827 36793.43555077005 0.5833513083473998 0.6584808275534206 0.7282716924557031 0.6665034143978141 1.0499376646757927 0.8176690891793527 1.1298880426763136 0.963316507902786 0.7998361840114142 1.0 15.167160772377041 -6.2499016768993885 24.448432292481485 0.9596408033736556 0.6640409827344234 0.6954606739154563 0.09754327342712608 319.5312151732405 677087.0788889843 0.028587304975250152 0.036569143202835656 5.624686521639906e-07 6.2499016768993885 -0.2955998206392323 YIFDNVAK ddPTM_PC-9_Lapatinib_30min_R1 2 YIFDNVAK 8 0 Q15293;Q15293-2 Q15293 RCN1 Reticulocalbin-1 0 ; 93.162 0.034239 5931600.0 70452.0 56609.0 72341.0 64826.0 57680.0 61723.0 64186.0 49091.0 57716.0 59074.0 False True 69447.34156068567 56477.925338546585 66393.40222433538 69593.52029319663 54287.375803243114 59083.25117334054 67509.23701548985 51371.94707550642 51215.41630357605 69284.86218884295 1.0023450919394177 0.8151553391938667 0.9582670748968715 1.0044549140259875 0.7835387715036127 0.8527584425628664 0.9743721049987305 0.7414599012333595 0.7392006664310483 1.0 16.080252556865716 -6.264808734299221 24.997976634694766 0.8421290067407247 0.9367206902708591 0.19373880347985584 0.09530093157783959 526.9158884997736 3909302.5186575954 0.029416274621639135 0.034698084188887944 5.434896346455811e-07 6.264808734299221 0.09459168353013447 YILGNPLTPGVTQGPQIDK ddPTM_PC-9_Lapatinib_30min_R1 2 YILGNPLTPGVTQGPQIDK 19 0 P00352 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ; 235.71 6.763500000000001e-43 25269000.0 167941.0 144632.0 139729.0 154299.0 115326.0 105009.0 152267.0 143479.0 111428.0 156117.0 False True 165546.1305433923 144297.11349016332 128241.02098953785 165646.66318637526 108542.75141963961 100518.00985793497 160150.640211847 150145.55813584122 98877.80525114127 183101.61543717375 0.9041216274806426 0.788071220156301 0.700381701621525 0.9046706813092663 0.5928006214499132 0.5489739105683912 0.8746544361690695 0.8200121980210464 0.5400160179639073 1.0 17.482284993987783 -3.8950549367297898 1.1230507456364207 0.7352899135814676 1.7754189354012224 0.08619071474132489 0.14831689216605418 24.68668512954483 5.847805335138192 0.04440732665354389 48.76469922280715 0.0001273341997528913 3.8950549367297898 1.0401290218197548 YILGNPLTPGVTQGPQIDKEQYDK ddPTM_PC-9_Lapatinib_30min_R1 2 YILGNPLTPGVTQGPQIDKEQYDK 24 1 P00352 P00352 ALDH1A1 Retinal dehydrogenase 1 0 ; 124.94 1.3222e-07 51494000.0 181644.0 172021.0 202882.0 210245.0 185357.0 167477.0 197851.0 176788.0 156871.0 191613.0 False True 179053.72325056978 171622.69594343848 186201.82510716765 225707.11865676014 174454.66568588323 160314.39911795527 208094.75668762205 185002.21587632404 139202.5360551369 224733.05174172638 0.7967396066705248 0.7636735879005249 0.828546685340968 1.0043343286956883 0.7762750709511772 0.7133547908306607 0.9259641831713039 0.8232087556437278 0.619412832141464 1.0 17.777852793335008 YIPRDCSQK ddPTM_PC-9_Lapatinib_30min_R1 1 YIPRDCSQK 9 1 Q9NUY8-2;Q9NUY8;C9IZ32;C9JAM5 Q9NUY8-2 TBC1D23 TBC1 domain family member 23 0 104.75 0.023865 3161800.0 25409.0 27658.0 15912.0 18232.0 20858.0 23374.0 21712.0 19939.0 20011.0 14670.0 False True 25046.663000560067 27593.959600302453 14603.77678209625 19572.842100169066 19631.17344840577 22374.348507455277 22836.1411223681 20865.43873089819 17757.150454828134 17205.689953453726 1.4557197687694245 1.603769431795641 0.8487760050078557 1.1375796119260058 1.1409698478534522 1.3004040272714572 1.3272435562971518 1.2127057262652716 1.0320510542074317 1.0 14.070598125298746 -5.238101094745303 24.99763575453279 1.1470747081772021 1.5297446823419754 0.5695047304792896 0.1397170389443317 611.5043170815668 654979.9618606421 0.036979272804827414 0.09770985996535055 5.7796149430053696e-06 5.238101094745303 0.3826699741647732 YIQHTYR ddPTM_PC-9_AZD4547_30min_R2 2 YIQHTYR 7 0 J3KTF8;J3QQX2;P52565;J3KRY1;P52565-2 J3KTF8 ARHGDIA Rho GDP-dissociation inhibitor 1 0 ; 121.99 0.0045165 27997000.0 87384.0 85095.0 124392.0 147969.0 147787.0 115329.0 104342.0 141876.0 106601.0 137216.0 False True 115170.29429988701 112600.2946265785 122742.48080371102 113857.0331482609 127269.3260393097 108117.45939844851 113628.235862762 119952.32418614475 112235.71122974514 132412.10960529983 0.8697867184745562 0.8503776200093986 0.9269732290316007 0.8598687347226114 0.9611607761456261 0.8165224443650211 0.8581408165874732 0.9059014658380129 0.8476242208080708 1.0 17.014675542719537 -11.098246431194022 3.4590996030899195 1.0041286947167893 0.8784709754347403 0.45259390778396336 0.040442129008982516 8086870.988580857 12985168.69156672 213524.3494899566 0.00941687143376624 7.975420105481662e-12 11.098246431194022 -0.12565771928204905 YIQHTYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YIQHTYR 7 0 J3KTF8;J3QQX2;P52565;J3KRY1;P52565-2 J3KTF8 ARHGDIA Rho GDP-dissociation inhibitor 1 0 ; 116.9 0.0063712 12770700.0 81564.0 74686.0 80630.0 87310.0 109938.0 92422.0 104839.0 92643.0 93019.0 82164.0 False True 95371.17423756853 82100.33249742129 82552.524990978 82418.30376283934 88396.4380965364 87575.2276203676 94907.89095136966 90211.21941337238 94379.22690034122 97059.68279013409 0.982603399227911 0.8458747250899383 0.8505336368085605 0.849150763670299 0.9107431175895179 0.902282236072478 0.9778302197482233 0.9294406989607652 0.972383426230759 1.0 16.566584524652093 -7.056910442520793 1.6268729968701126 0.9669187239738521 0.878883821710389 0.46287234915394626 0.04158308285671536 0.35234273427178286 1.8672281278925456 0.020751523684298386 0.014897080441727415 8.7718168939053e-08 7.056910442520793 -0.08803490226346311 YIQHTYR ddPTM_PC-9_Lapatinib_30min_R1 1 YIQHTYR 7 0 J3KTF8;J3QQX2;P52565;J3KRY1;P52565-2 J3KTF8 ARHGDIA Rho GDP-dissociation inhibitor 1 0 75.189 0.027766000000000002 9580600.0 33817.0 33295.0 42167.0 36962.0 44885.0 47217.0 37488.0 33499.0 42443.0 37052.0 False True 33334.7633787217 33217.90747313871 38700.1920293271 39680.30878161742 42244.9525473053 45197.63897820295 39428.94520980725 35055.48583411196 37662.62239539606 43456.38883131338 0.7670854453212564 0.7643964067534962 0.8905524151938022 0.9131064464570736 0.972122941721859 1.040068910319462 0.9073221744876309 0.8066819811049745 0.8666763025706704 1.0 15.407280672991462 -5.341969404643391 2.78415982281109 0.9263229914127008 0.7600587279283921 0.5151192832196001 0.062472739857592524 0.24875285823004822 3.7010052070288224 0.01925081456935449 0.05227776877736667 4.550201144654586e-06 5.341969404643391 -0.16626426348430867 YIS(ph)FEER ddPTM_PC-9_AZD4547_30min_R2 1 YISFEER 7 0 Q14192 Q14192 FHL2 Four and a half LIM domains protein 2 1 YIS(1)FEER 85.161 0.019469999999999998 1923300.0 6983.1 5922.8 9927.9 11970.0 11935.0 10668.0 6764.0 8753.8 9802.1 9634.6 True False 9203.580542496811 7837.229273333329 9796.249559225374 9210.501434656475 10278.03126309596 10000.928273570791 7365.982896395734 7401.101352312392 10320.218994616242 9297.295586544002 0.9899201823611132 0.8429579548569124 1.0536665708900887 0.9906645807827016 1.105486124155435 1.0756814366583287 0.792271561964378 0.7960488384411509 1.110023758903903 1.0 13.182595408271473 -7.2435703365168695 24.94891530893214 0.9075900902736361 1.0076320760017479 0.11966287784737062 0.10922604429469948 1548.6216672570065 2162201.727536901 0.04299063109093877 0.033230054955272655 5.7072863586494616e-08 7.2435703365168695 0.10004198572811174 YIS(ph)FEER ddPTM_PC-9_Lapatinib_30min_R1 1 YISFEER 7 0 Q14192 Q14192 FHL2 Four and a half LIM domains protein 2 1 YIS(1)FEER 75.043 0.033296 1377900.0 10572.0 7138.6 10159.0 9009.9 9332.0 9493.0 8338.9 7777.4 11083.0 8676.2 True False 10421.241341332649 7122.071010294276 9323.766234874047 9672.51810214531 8783.110107417906 9087.00651926383 8770.647439448938 8138.766396794595 9834.715830836054 10175.869609690199 1.0241130970672805 0.6998980218370846 0.9162623532435284 0.9505347919291771 0.8631311567764187 0.8929955736274889 0.8619064292153363 0.7998104052988526 0.9664742383757283 1.0 13.312864469174043 -8.455031321859547 6.638225279561374 0.9998045897678581 0.8738734422447691 0.22073553487091102 0.08163378214558904 0.29390452487749774 22.291995841974707 0.0744646156019638 0.019278034453096973 3.5072657820226533e-09 8.455031321859547 -0.12593114752308898 YIS(ph)PDQLADLYK ddPTM_PC-9_AZD4547_30min_R2 5 YISPDQLADLYK 12 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 1 YIS(0.999)PDQLADLY(0.001)K;Y(0.007)IS(0.993)PDQLADLYK;Y(0.003)IS(0.997)PDQLADLYK;YIS(1)PDQLADLYK;YIS(0.96)PDQLADLY(0.04)K 117.92 0.0008560000000000001 10912400.0 52556.00000000001 42998.9 58620.7 75603.6 68426.5 65007.6 54604.700000000004 62324.0 51046.8 59854.2 True False 69267.71476728986 56897.45353568116 57843.35121591508 58174.358083976076 58926.661602365864 60942.66449540503 59464.41251667947 52693.25786304436 53745.029633892336 57758.722676200596 1.1992598097366085 0.9850885009118403 1.0014652079511681 1.0071960630103536 1.0202209964495375 1.0551248655039314 1.029531294347368 0.9122995700311175 0.9305093177906772 1.0 15.817751217185071 -4.759695313132187 24.999784217215964 0.9953170346021939 1.1992600639263957 0.6942958687644778 0.040945338712476784 28.891236289274943 414011.93231959775 0.011391607522239574 0.07104449999102914 1.7390204409978816e-05 4.759695313132187 0.20394302932420183 YIS(ph)PDQLADLYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YISPDQLADLYK 12 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 1 YIS(0.99)PDQLADLY(0.01)K;Y(0.002)IS(0.998)PDQLADLYK 105.65 0.0017652000000000002 4686700.0 18177.300000000003 19136.3 21308.7 24599.2 23036.0 20868.4 20670.2 19861.6 18809.5 16506.7 True False 21254.35787196009 21036.025396599147 21816.780221694764 23220.98657568244 18522.261165309646 19774.024367281378 18712.169016711392 19340.25404510471 19084.55335342207 19499.23404303469 1.090009885775608 1.0788129087620966 1.118853190517395 1.1908666014487475 0.9498968587397397 1.014092365045736 0.9596361054702842 0.9918468593392381 0.9787334882643379 1.0 14.251129833574648 -6.272596641625089 24.99996949028637 0.9824096145067063 1.1166638484801916 0.8093306595941477 0.03262741615969916 316.689809027909 709602.3264729078 0.010327822860128935 0.011821315519734404 5.338304694292068e-07 6.272596641625089 0.13425423397348535 YIS(ph)PDQLADLYK ddPTM_PC-9_Lapatinib_30min_R1 2 YISPDQLADLYK 12 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 1 YIS(1)PDQLADLYK;Y(0.009)IS(0.991)PDQLADLYK 101.43 0.0027226999999999998 4178000.0 16626.9 14417.3 15739.9 12906.4 15047.6 14491.6 11648.0 14537.5 12153.2 12302.6 True False 16389.79735699997 14383.917627646279 14445.826179771046 13855.57971048826 14162.529752719858 13871.828049569554 12251.076445898285 15212.965321752965 10784.378637130449 14429.088017815935 1.1358858811286687 0.9968694909814201 1.0011600290977811 0.9602533225509783 0.9815263262122352 0.9613794047442001 0.8490541072846456 1.0543261849237566 0.7474054232543819 1.0 13.816692497552305 -1.5228787491999425 0.471740334541362 0.9232097612444027 6.080626076966344 0.3640132215378101 0.0804181064666245 102.6041412090736 1.1741048924860296 0.04400209096464866 516.4755825681924 0.029999999729243287 1.5228787491999425 5.1574163157219415 YISENES(ph)PRPSQK ddPTM_PC-9_AZD4547_30min_R2 2 YISENESPRPSQK 13 1 O94782 O94782 USP1 Ubiquitin carboxyl-terminal hydrolase 1 1 YISENES(0.999)PRPS(0.001)QK;YISENES(0.66)PRPS(0.34)QK 139.21 9.3442e-05 4102300.0 21624.5 28518.0 30206.0 40390.0 32636.0 30920.0 31775.0 39273.0 30825.0 33475.0 True False 28500.641182457995 37735.88580011478 29805.44870375022 31078.709519279455 28105.054738366118 28986.56751207434 34602.91344366861 33204.260253760025 32454.34656951528 32303.050438996994 0.8822894678717821 1.1681833538098043 0.9226821708382187 0.9620982878372537 0.8700433660728537 0.8973322060346686 1.0711964651454453 1.0278985978882995 1.0046836484004507 1.0 14.9793827873608 -7.2691239228367035 24.91912433837681 1.0282695587416042 0.9559497147995466 0.17039090201787443 0.0810109385586493 1188.1998305773525 3853029.7570778956 0.03456552624986891 0.023831647870899267 5.3811621297925424e-08 7.2691239228367035 -0.0723198439420576 YISENES(ph)PRPSQK ddPTM_PC-9_Lapatinib_30min_R1 1 YISENESPRPSQK 13 1 O94782 O94782 USP1 Ubiquitin carboxyl-terminal hydrolase 1 1 YIS(0.004)ENES(0.989)PRPS(0.007)QK 58.658 0.030442 18934000.0 43605.0 45451.0 53745.0 44797.0 46864.0 36906.0 36316.0 35016.0 43573.0 34995.0 True False 42983.18470382236 45345.76100200109 49326.29356169956 48091.520818411256 44107.55165816897 35327.616412087955 38196.26478444728 36642.97119219273 38665.34989596852 41043.83912209359 1.0472505892043815 1.1048128530840042 1.2017953148819256 1.1717110739897612 1.0746448821944197 0.8607288491458726 0.9306211504928767 0.8927764063003574 0.942050030479611 1.0 15.324878062330711 -6.618178533422008 4.864756371017386 0.9197235697624425 1.1333924307809045 0.7881902107172332 0.0510284569165434 0.09302947602978641 3.719398832571723 0.017653674527294536 0.01764354918443067 2.408914948130602e-07 6.618178533422008 0.21366886101846194 YISPDQLADLYK ddPTM_PC-9_Lapatinib_30min_R1 1 YISPDQLADLYK 12 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 157.68 0.0020023 80151000.0 372150.0 305340.0 482550.0 345970.0 328600.0 319100.0 342380.0 355030.0 370150.0 395440.0 False True 366843.07275604864 304633.00399003417 442876.6016968678 371413.78792208707 309272.39405245695 305452.83685843146 360106.7611217938 371525.98990073573 328459.8091477004 463791.27710932196 0.7909658737923583 0.6568321118256564 0.9549049832441667 0.8008209861923292 0.6668352970760103 0.6585997881681419 0.7764414272002613 0.8010629096268276 0.7082060947650766 1.0 18.82311616076513 -10.814372868547593 3.822461277801255 1.0004742317505975 0.7576325270017114 0.4150293487204081 0.08648009374241392 129743965.40258227 231010620.4628038 718010.8834854831 0.022346834209704236 1.533299985092262e-11 10.814372868547593 -0.2428417047488861 YKAEDEVQR ddPTM_PC-9_AZD4547_30min_R2 1 YKAEDEVQR 9 1 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 79.48899999999999 0.026017000000000002 34144000.0 37485.0 39786.0 50493.0 64962.0 46130.0 51478.0 37961.0 45799.0 49007.0 39190.0 False True 49404.4502635639 52646.04644236506 49823.429828459884 49986.01455289508 39725.64576176094 48259.07252220451 41339.45545979872 38721.81690632129 51597.40997022658 37817.97002850764 1.3063749912097935 1.3920907548099446 1.3174538398254159 1.321752979211074 1.050443631210646 1.276088390937595 1.0931167227811684 1.0238999310944592 1.364362231270791 1.0 15.206784304751338 -6.175400540179052 6.848212788864502 1.1411110466130874 1.3391710738285652 0.45005719052718596 0.10805757994233092 0.23925477829046163 16.24672777202287 0.03055389661077643 0.03957542055747085 6.677278029384213e-07 6.175400540179052 0.19806002721547777 YKAEDEVQR ddPTM_PC-9_Lapatinib_30min_R1 1 YKAEDEVQR 9 1 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 74.165 0.03607 38729000.0 77552.0 66740.0 80370.0 62206.0 76446.0 75593.0 76079.0 60924.0 72829.0 59770.0 False True 76446.09425870505 66585.46763049348 73762.28883717181 66780.83675313284 71949.59657861869 72360.06360588965 80017.99836259401 63754.751453996716 64626.23109663073 70101.16486148119 1.0905110408616083 0.949848233792767 1.0522262929999089 0.9526351935105606 1.0263680599429406 1.0322234123908214 1.1414646036297447 0.9094677895863088 0.9218995322592878 1.0 16.09715079705096 YKDAIHFYNK ddPTM_PC-9_AZD4547_30min_R2 2 YKDAIHFYNK 10 1 P31948-2;P31948;P31948-3 P31948-2 STIP1 Stress-induced-phosphoprotein 1 0 ; 85.355 0.0053879 9934300.0 118637.0 111012.0 157024.0 209993.0 181588.0 155177.0 117540.0 167819.0 128773.0 154821.0 False True 156361.0981971037 146894.4580420204 154941.759162341 161582.3582095084 156377.64063703985 145473.75765915788 128000.83229484867 141886.42964697804 135579.67788471025 149400.76391384506 1.0465883446705297 0.9832242767294684 1.0370881319702707 1.0815363588280453 1.0466990699406205 0.9737149519733931 0.8567615649452965 0.9497035084024047 0.9074898570324245 1.0 17.18882799935043 -6.948084656196149 4.367749177129972 0.9229075168283821 1.037447066941303 0.6219987029385519 0.040586835824529356 0.13318392182709948 5.3750567276063705 0.014819998687563176 0.012749654631538525 1.1269777551360201e-07 6.948084656196149 0.11453955011292083 YKDAIHFYNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YKDAIHFYNK 10 1 P31948-2;P31948;P31948-3 P31948-2 STIP1 Stress-induced-phosphoprotein 1 0 55.083999999999996 0.041227999999999994 2733400.0 48228.0 39048.0 52646.0 65636.0 62441.0 62899.0 69397.0 58231.0 58448.0 40436.0 False True 56392.04785358059 42924.42738075823 53901.28030106682 61958.627714783164 50206.13428646898 59600.465712638805 62823.21376922914 56702.49795084445 59302.691427247504 47766.72670880012 1.180571743953965 0.8986261010187707 1.1284273387553794 1.2971085101246524 1.0510691802798253 1.2477402120513847 1.3152086839070585 1.1870710399839495 1.2415062850920053 1.0 15.54371839676513 -5.5182721809974895 24.748190678586326 1.2017591141286628 1.033080857939939 0.2169341722565168 0.11363009729007228 199.39598144743 1071228.1422191968 0.02889484543380685 0.0517826777639705 3.0319903798903683e-06 5.5182721809974895 -0.16867825618872367 YKDLDEDELLGNLS(ph)ETELK ddPTM_PC-9_AZD4547_30min_R2 6 YKDLDEDELLGNLSETELK 19 1 Q9NYL9;H0YNU8 Q9NYL9 TMOD3 Tropomodulin-3 1 YKDLDEDELLGNLS(0.714)ET(0.286)ELK;YKDLDEDELLGNLS(0.624)ET(0.376)ELK;YKDLDEDELLGNLS(0.769)ET(0.231)ELK;YKDLDEDELLGNLS(0.81)ET(0.19)ELK;YKDLDEDELLGNLS(0.747)ET(0.253)ELK;YKDLDEDELLGNLS(0.714)ET(0.286)ELK 166.65 5.8092e-10 41215800.0 360302.7 416313.4 349726.9 335465.0 359836.3 436751.0 439363.7 401891.2 435290.9 391615.9 True False 474871.4638382754 550878.5650977457 345089.29279850284 258128.72713258426 309879.24097166094 409440.89092710183 478466.2181397319 339788.14958103286 458299.4883100144 377905.54653960286 1.256587706072504 1.4577149505796314 0.9131628153077107 0.6830509091391002 0.8199912486311892 1.0834476886519955 1.2661000149930075 0.8991351217054036 1.2127355433297051 1.0 18.52766616770115 -5.264721237756874 24.99916892488174 0.9780212439917461 1.3571513419182792 0.43119033899481396 0.17097213674416248 257.5111422416488 1961576.6074644611 0.04829765914732109 0.10772444205163795 5.435991415732357e-06 5.264721237756874 0.3791300979265332 YKDLDEDELLGNLS(ph)ETELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 YKDLDEDELLGNLSETELK 19 1 Q9NYL9;H0YNU8 Q9NYL9 TMOD3 Tropomodulin-3 1 YKDLDEDELLGNLS(0.767)ET(0.233)ELK;YKDLDEDELLGNLS(0.92)ET(0.08)ELK;YKDLDEDELLGNLS(0.985)ET(0.015)ELK;YKDLDEDELLGNLS(0.729)ET(0.271)ELK;YKDLDEDELLGNLS(0.913)ET(0.087)ELK;YKDLDEDELLGNLS(0.737)ET(0.263)ELK;YKDLDEDELLGNLS(0.873)ET(0.127)ELK;YKDLDEDELLGNLS(0.749)ET(0.251)ELK 135.62 9.6617e-10 16285500.0 239301.0 265742.5 207014.6 267856.0 270139.0 228318.0 274743.0 212533.7 223974.7 204102.9 True False 279809.93288980855 292123.65916900046 211950.61317124288 252848.89672086915 217207.20215903746 216344.60214913226 248717.35407293253 206954.9155730696 227249.9062689972 241105.14009233308 1.1605307658835193 1.211602784814664 0.8790796126954189 1.048708030961259 0.9008816737621449 0.8973039814343295 1.03157217626171 0.8583596164470596 0.9425344734748089 1.0 17.87930288235225 -5.25585673926383 24.998731634907887 0.9432908619835189 1.1860668017763019 0.7065272908661866 0.06219066568359008 223.86650745933585 1002453.3105090315 0.015198673475000037 0.03791255281917551 5.548086975404483e-06 5.25585673926383 0.242775939792783 YKDLDEDELLGNLS(ph)ETELK ddPTM_PC-9_Lapatinib_30min_R1 4 YKDLDEDELLGNLSETELK 19 1 Q9NYL9;H0YNU8 Q9NYL9 TMOD3 Tropomodulin-3 1 YKDLDEDELLGNLS(0.711)ET(0.289)ELK;YKDLDEDELLGNLS(0.745)ET(0.255)ELK;YKDLDEDELLGNLS(0.679)ET(0.321)ELK;YKDLDEDELLGNLS(0.926)ET(0.074)ELK 152.66 1.4424000000000001e-05 45403100.0 604828.0 710872.0 569664.0 627184.0 657950.0 586125.0 563809.0 615661.0 577442.0 538104.0 True False 596203.0418081295 709226.0195598466 522828.4248866311 673309.2035844915 619250.6745794697 561057.800074109 593000.2712813754 644266.8576409806 512404.4012261687 631114.5594214905 0.9446827567322127 1.1237674824202388 0.8284207947379322 1.066857345521673 0.9812016936308745 0.8889951779727616 0.9396079720058234 1.0208397952846249 0.8119039460852603 1.0 19.267542380291438 -6.559191429345274 16.32407749497902 0.9341458743343076 0.9932139131105167 0.09085673454966359 0.08991315013982012 11.599246400429404 5211.557508022451 0.028138017238843654 0.028140868442060717 2.759361310342455e-07 6.559191429345274 0.05906803877620903 YKDLDEDELLGNLSET(ph)ELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YKDLDEDELLGNLSETELK 19 1 Q9NYL9;H0YNU8 Q9NYL9 TMOD3 Tropomodulin-3 1 YKDLDEDELLGNLS(0.346)ET(0.654)ELK 96.54 0.00047038 5633800.0 17116.0 19290.0 14362.0 19370.0 19635.0 18271.0 19100.0 16156.0 16258.0 14438.0 True False 20013.400743590555 21204.983716831233 14704.444548188307 18284.761698387305 15787.662701026862 17312.836595742752 17290.709727974936 15731.922118696964 16495.74249288583 17055.495108854888 1.1734283065872406 1.2432933539303712 0.8621528987777106 1.072074518018196 0.9256642859244941 1.0150884794164818 1.013791134037377 0.9223960968760884 0.9671805120639129 1.0 14.057949015516414 -5.249500789247084 24.994140359929396 0.9744306526109269 1.2083608613320056 0.7263679614839069 0.05794446827783289 350.8491570041007 734519.9164785281 0.013738850073843307 0.03573183501031493 5.62988094270225e-06 5.249500789247084 0.23393020872107873 YKDNPFSLGES(ph)FGSR ddPTM_PC-9_AZD4547_30min_R2 1 YKDNPFSLGESFGSR 15 1 Q8N6H7;E9PMU9;H0YDN9;A0A0D9SF70;G5E9L0;Q8N6H7-3;Q8N6H7-2;E9PQP3 Q8N6H7 ARFGAP2 ADP-ribosylation factor GTPase-activating protein 2 1 YKDNPFS(0.001)LGES(0.93)FGS(0.069)R 90.755 0.0019439 14209000.0 66171.0 48790.0 79886.0 106210.0 102980.0 96272.0 85800.0 83910.0 82047.0 106200.0 True False 87212.00155769757 64560.41335954838 78826.65944341481 81724.92542814233 88683.00456419133 90252.09662103548 93436.03378337556 70943.63755997768 86383.83691772968 102481.97032476407 0.8509984856977656 0.6299685023127214 0.7691758774115498 0.7974566176777932 0.8653522593599245 0.8806631677262617 0.911731434195478 0.6922548164829208 0.8429174092182302 1.0 16.64501059284064 -5.901839366031407 2.4479369361994605 0.852546154928582 0.7352736257830872 0.2520293403011532 0.08794136095055734 0.4138129409394646 5.031934499373351 0.026467783758277325 0.04349070882571949 1.253604764234687e-06 5.901839366031407 -0.1172725291454948 YKDNPFSLGES(ph)FGSR ddPTM_PC-9_Lapatinib_30min_R1 1 YKDNPFSLGESFGSR 15 1 Q8N6H7;E9PMU9;H0YDN9;A0A0D9SF70;G5E9L0;Q8N6H7-3;Q8N6H7-2;E9PQP3 Q8N6H7 ARFGAP2 ADP-ribosylation factor GTPase-activating protein 2 1 YKDNPFSLGES(0.992)FGS(0.007)R 69.07 0.012506 7045000.0 44428.0 25272.0 36191.0 33898.0 38221.0 46104.0 37872.0 32911.0 52485.0 55555.0 True False 43794.44857290266 25213.484236707052 33215.51568129999 36390.972000413065 35972.91592537719 44132.2393936732 39832.8268508808 34440.165207512415 46573.58660844808 65157.60772761565 0.6721310081852702 0.38696147872876646 0.5097718722294697 0.5585068769335669 0.5520908022860214 0.6773152197079313 0.6113304069940326 0.5285670608332615 0.7147835568663591 1.0 15.991646015597311 -14.522877231860736 0.17874462354327567 2.784232688499638 0.4805991867574932 0.7268407828387615 0.08141529762502864 67.3160904635622 0.6446053923113403 42.39876752225259 0.2536695751409721 3.0000104543504562e-15 14.522877231860736 -2.3036335017421448 YKPAVNQIECHPYLTQEK ddPTM_PC-9_Lapatinib_30min_R1 1 YKPAVNQIECHPYLTQEK 18 1 P15121;E9PCX2 P15121 AKR1B1 Aldose reductase 0 48.677 0.036543 9375700.0 52989.0 51480.0 53297.0 60945.0 56222.0 64798.0 53812.0 52467.0 54935.0 57744.0 False True 52233.3671430075 51360.80122292179 48915.1263923695 65427.09860656011 52915.13249670483 62026.74059151564 56598.1220558618 54904.808360200375 48747.64180880436 67724.97346095643 0.7712571075885342 0.7583731465399745 0.7222612855000845 0.9660704945758147 0.7813237834225287 0.9158621616481573 0.8357053412282357 0.8107025452265861 0.7197882748068917 1.0 16.047400302635225 -12.140685768965676 2.15064753037828 4.991488928203407 0.8127744495653803 0.36382414263505325 0.07560971094108894 7752071.033523424 319437.08742536925 151645317.97181153 0.01921410294028209 7.232929483730121e-13 12.140685768965676 -4.178714478638026 YKPVCNQVECHPYFNQR ddPTM_PC-9_AZD4547_30min_R2 2 YKPVCNQVECHPYFNQR 17 1 B4DK69;P52895;H0Y804;S4R3P0;Q04828 B4DK69;Q04828 AKR1C2;AKR1C1 Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 ; 127.05 1.5835e-05 77172000.0 216445.0 193605.0 283630.0 365320.0 300300.0 290540.0 243580.0 300490.0 245026.0 237149.0 False True 285270.0076643221 256184.03009787572 279868.8808794504 281101.11813773593 258608.5285553174 272372.48787057115 265258.14812301507 254056.1750732654 257977.57412950677 228846.48569253722 1.2465562090719267 1.1194580040091477 1.2229546808748615 1.2283392392374535 1.1300524356872426 1.1901973807739068 1.159109554688107 1.1101598274687872 1.127295327908632 1.0 17.804020611632637 -8.91126642519257 0.3775280318842802 0.9796611330572943 1.2034520781597835 0.6978490296980602 0.038201304593442814 1.2476086464189509 0.3759372650044163 0.08647171807263292 0.031816006099776334 1.2266864690131353e-09 8.91126642519257 0.2237909451024892 YKPVCNQVECHPYFNQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YKPVCNQVECHPYFNQR 17 1 B4DK69;P52895;H0Y804;S4R3P0;Q04828 B4DK69;Q04828 AKR1C2;AKR1C1 Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 ; 118.52 5.0205e-05 69083000.0 147902.0 139942.0 123381.0 149904.0 188214.0 153069.0 158607.0 137298.0 128735.0 134093.0 False True 172938.88740234447 153834.516915542 126322.87096504816 141505.36487532535 151334.81780550434 145041.79217742584 143582.5967447604 133694.07297925567 130617.5058323076 158402.9994203959 1.0917652319409106 0.9711591161684424 0.7974777714264852 0.8933250342045302 0.9553784862612805 0.9156505413921494 0.9064386234486465 0.8440122565131255 0.82458985189828 1.0 17.273240128086414 -4.912677178840248 3.6766717152869157 0.889681259747429 1.0905751565076827 0.5347698795887168 0.05730082577479283 0.18303627861472377 4.443356460382872 0.01463538038296514 0.08084022066143931 1.2227081898097321e-05 4.912677178840248 0.2008938967602537 YKPVCNQVECHPYFNQR ddPTM_PC-9_Lapatinib_30min_R1 2 YKPVCNQVECHPYFNQR 17 1 B4DK69;P52895;H0Y804;S4R3P0;Q04828 B4DK69;Q04828 AKR1C2;AKR1C1 Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 ; 118.52 5.0205e-05 86195000.0 265294.0 295558.0 300579.0 259796.0 282855.0 297373.0 244315.0 260543.0 312005.0 266719.0 False True 261510.85891103937 294873.6536100299 275866.5548884938 278902.2644940507 266218.02501432644 284655.05000032095 256964.4352575237 272648.7789389843 276863.71134169446 312821.0237692718 0.8359759704127898 0.9426273530372454 0.8818670547282825 0.8915713564691911 0.8510234440338689 0.9099613784598912 0.8214423447672545 0.8715807385761981 0.8850546808065609 1.0 18.254977949577032 -8.743775630374461 5.28729287430666 0.9999999307687285 0.877266273735059 0.5525966186028831 0.03333050117292861 6.527843857014181 156.1570398210597 0.031274441183479225 0.008123102160597877 1.8039494748548672e-09 8.743775630374461 -0.12273365703366945 YKPVCNQVECHPYFNR ddPTM_PC-9_AZD4547_30min_R2 2 YKPVCNQVECHPYFNR 16 1 A0A0A0MSS8;P42330;S4R3Z2;P42330-2 A0A0A0MSS8;P42330-2 AKR1C3 Aldo-keto reductase family 1 member C3 0 ; 112.02 0.00017725 61991000.0 170139.0 152788.0 207983.0 295900.0 225624.0 230932.0 185464.0 248620.0 187057.0 215397.0 False True 224239.66288895532 202173.7330678147 205225.0095263219 227684.82660942787 194300.00215372944 216491.78553358195 201969.93670862433 210201.49171924277 196944.45113556593 207856.01659174394 1.078822093128971 0.9726624053654892 0.9873421654635589 1.0953968537587742 0.934781707740314 1.041546879823064 0.971681936469125 1.0112841339209615 0.9475042116408411 1.0 17.665224983195074 -6.794954398205648 0.726072436802558 0.9816830144801484 1.0233367396511446 0.11442739852027817 0.04772275239844318 1.8049057181182384 2.0784149102233047 0.033764612930180224 0.03266079683201394 1.6034137435201546e-07 6.794954398205648 0.04165372517099619 YKPVCNQVECHPYFNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YKPVCNQVECHPYFNR 16 1 A0A0A0MSS8;P42330;S4R3Z2;P42330-2 A0A0A0MSS8;P42330-2 AKR1C3 Aldo-keto reductase family 1 member C3 0 ; 142.95 3.9089e-06 68994000.0 116228.0 126566.0 118035.0 139296.0 156289.0 142722.0 136830.0 106153.0 114140.0 111187.0 False True 135903.10479236065 139130.63603444624 120849.40205023038 131491.6967237255 125665.29237997404 135237.40707227835 123868.47183658667 103366.59622840049 115809.0815683351 131344.32294419204 1.0347086325924084 1.0592816873673527 0.9200961209536179 1.0011220414878235 0.956762268540293 1.0296402923310242 0.9430820385683373 0.7869894481265153 0.8817212573210504 1.0 17.002994319086042 -7.527554146099599 24.480045329961502 0.8736203244818268 0.9964507384094666 0.39063334993938315 0.06122280674619131 91.96882102049827 481526.9485954462 0.02774062887645086 0.0160989272698758 2.967876697395378e-08 7.527554146099599 0.12283041392763983 YKPVCNQVECHPYFNR ddPTM_PC-9_Lapatinib_30min_R1 2 YKPVCNQVECHPYFNR 16 1 A0A0A0MSS8;P42330;S4R3Z2;P42330-2 A0A0A0MSS8;P42330-2 AKR1C3 Aldo-keto reductase family 1 member C3 0 ; 86.49799999999999 0.0020143 76639000.0 148389.0 151489.0 172254.0 143040.0 159722.0 165539.0 156223.0 149417.0 167836.0 138014.0 False True 146272.94564879016 151138.23652795676 158091.9410396685 153559.63876745192 150327.4659855342 158459.28286025662 164311.46253499025 156359.45929357634 148932.54228856802 161869.53600790427 0.9036471547162988 0.9337040202584909 0.9766627182519921 0.9486629946227401 0.9286952300783362 0.9789320879533433 1.0150857696099576 0.9659597670431398 0.9200776499494968 1.0 17.30447196912114 -6.770878071839834 24.971340458505438 0.9763257173965648 0.9407303379294745 0.2992650979543149 0.02874777178858548 289.96006483006187 767124.0032308311 0.010612628049542147 0.009482511887411078 1.694813552504393e-07 6.770878071839834 -0.03559537946709035 YLAADKDGNVTCER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YLAADKDGNVTCER 14 1 Q16658 Q16658 FSCN1 Fascin 0 73.219 0.027202999999999998 15437000.0 44684.0 53013.0 40908.0 63783.0 62189.0 48472.0 55110.0 57722.0 48877.0 55061.0 False True 52248.11865077126 58275.78028928851 41883.401864453954 60209.44529727608 50003.51187747187 45930.04298992077 49889.581838151775 56206.858661514416 49591.733658800615 65043.12343736381 0.8032842810983075 0.8959560551455956 0.6439328195053157 0.9256850242632868 0.7687747641089991 0.7061475612276087 0.7670231563555705 0.8641475945668773 0.7624439147138621 1.0 15.98910891831845 -11.087806473547907 2.5538878368178204 1.0159725405316977 0.7936427160407236 0.37104686188038827 0.08083064279648693 8422250.111183185 7662752.778726203 913888.0653515405 0.020705071518718355 8.16946330632806e-12 11.087806473547907 -0.22232982449097416 YLAADKDGNVTCER ddPTM_PC-9_Lapatinib_30min_R1 1 YLAADKDGNVTCER 14 1 Q16658 Q16658 FSCN1 Fascin 0 73.273 0.027041000000000003 22347000.0 99765.0 102490.0 101680.0 90229.0 105880.0 97960.0 99324.0 88327.0 93736.0 80399.0 False True 98342.33280533973 102252.69070196665 93320.26289615034 96864.7416551204 99652.3465680892 93770.47915591321 104466.51072393556 92430.99487356671 83178.46459616066 94295.86002506659 1.0429125178899419 1.0843815484029193 0.9896538710325468 1.0272427827623707 1.0568051083218148 0.9944283782022486 1.1078589314118914 0.9802232552839102 0.882100916986699 1.0 16.524906811611885 -7.993663131241928 24.66166135769206 0.9377543250337771 1.0410872729728824 0.4877623243420427 0.04309196399338098 95.51053802848213 371705.7421944393 0.02220637752585834 0.010621093225611652 1.0146981504427462e-08 7.993663131241928 0.1033329479391053 YLAEFATGNDR ddPTM_PC-9_Lapatinib_30min_R1 2 YLAEFATGNDR 11 0 P62258;P62258-2;K7EM20 P62258 YWHAE 14-3-3 protein epsilon 0 ; 187.97 0.0026589 20450100.0 55167.0 56732.0 57353.0 68795.0 63437.0 53256.0 53307.0 62850.0 65425.0 54166.0 False True 54380.30846361123 56600.640539603686 52637.657728982325 73854.41379339242 59705.76038194066 50978.365025799496 56066.97562684576 65770.24044520545 58056.147544207204 63528.52092834177 0.8559983400990959 0.8909485017516381 0.8285673420345484 1.1625394817029966 0.939826073540842 0.8024484795309736 0.8825481029235293 1.0352868205351777 0.9138595814263134 1.0 15.955116810238813 -6.006443738836653 0.013339486192503056 1.8377555932080545 4.625094291397658e-05 0.07434028465092968 0.09915519093451312 7013.731209801004 23.465790043329356 1520.9661040195876 1712.8401114132848 9.852722727330472e-07 6.006443738836653 -1.8377093422651405 YLAEFATGNDRK ddPTM_PC-9_AZD4547_30min_R2 2 YLAEFATGNDRK 12 1 P62258;P62258-2;K7EM20 P62258 YWHAE 14-3-3 protein epsilon 0 ; 103.21 0.0013702999999999999 28092000.0 98183.0 54948.0 84469.0 100850.0 97504.0 86156.0 89427.0 86731.0 65248.0 90130.0 False True 129403.15166673352 72708.86643329513 83348.88586893582 77600.59061696785 83967.25264155067 80768.65170020287 97385.82975694563 73328.71683010862 68696.87607356801 86974.5761334371 1.487827333222092 0.8359783935220861 0.958313217198797 0.8922215441201161 0.9654229589199427 0.928646683788225 1.119704562946481 0.8431051933798114 0.7898500818006023 1.0 16.408306122504378 -4.7556499142182656 24.9989580273615 0.928348177833684 1.4878282337958029 0.7796280671458794 0.08961543508569529 86.87244135522573 375077.93632296665 0.022483294032503796 0.19531582245985307 1.7552948789419688e-05 4.7556499142182656 0.5594800559621189 YLAEFATGNDRK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YLAEFATGNDRK 12 1 P62258;P62258-2;K7EM20 P62258 YWHAE 14-3-3 protein epsilon 0 ; 106.26 0.0010712 23373000.0 57535.0 61275.0 56183.0 74230.0 76345.0 64352.0 70617.0 66287.0 73804.0 62004.0 False True 67274.53913195153 67357.9770476327 57522.615795214035 70071.13375690697 61385.745297168185 60977.26783477848 63927.64653719409 64547.03648688197 74883.24387654985 73244.83437660619 0.9184885146445014 0.9196276791520235 0.7853470662442551 0.9566699734293772 0.8380897549926647 0.83251287758054 0.8727939257599313 0.8812503576019796 1.022368942654978 1.0 16.160439395984817 -8.248162428101375 9.095707040520407 1.011316527959433 0.8739200807632915 0.5711297760287265 0.04697991615436497 0.1433511969665387 92.80856994231131 0.03357330665069044 0.01170589155938288 5.647257253340264e-09 8.248162428101375 -0.1373964471961414 YLAEFATGNDRK ddPTM_PC-9_Lapatinib_30min_R1 1 YLAEFATGNDRK 12 1 P62258;P62258-2;K7EM20 P62258 YWHAE 14-3-3 protein epsilon 0 134.75 3.6914e-05 10679000.0 53011.0 43755.0 48187.0 35466.0 30887.0 48929.0 36097.0 36250.0 43447.0 33989.0 False True 52255.053418973184 43653.6879857992 44225.25086719913 38074.28795110773 29070.28738617842 46836.42072906984 37965.92603602252 37934.307337131206 38553.54134280737 39863.953362504326 1.3108347018116826 1.0950667032151273 1.1094045406143036 0.9551056716547351 0.7292374422031527 1.1749065704337232 0.9523873784112172 0.9515942132526142 0.9671278960272537 1.0 15.282797170851827 -4.739792975331798 1.106839721917959 0.9631628097872477 1.4864216262455827 0.49257364601262854 0.10642275969162793 1.595693956112395 1.5189201402206503 0.03394877836123547 1.0034115003441888 1.820568502079674e-05 4.739792975331798 0.523258816458335 YLAEVAAGDDKK ddPTM_PC-9_AZD4547_30min_R2 2 YLAEVAAGDDKK 12 1 P63104;E7EX29;B0AZS6;P63104-2;B7Z2E6;H0YB80 P63104 YWHAZ 14-3-3 protein zeta/delta 0 ; 95.094 0.0029764 22299900.0 54162.0 49036.0 62597.0 62245.0 65551.0 65186.0 76423.0 70941.0 62231.0 62511.0 False True 71384.3893604148 64885.928048756155 61766.92287984679 47895.376925663484 56450.37514262289 61109.90911520305 83224.49894903165 59978.698512005445 65520.40361289555 60322.508916867584 1.1833789847632492 1.0756503536379358 1.0239448588746498 0.7939884760375213 0.9358094707303868 1.0130531738893787 1.3796591097317594 0.994300462447012 1.0861684102561342 1.0 15.880408813571297 -7.0309951796623045 24.99358262782747 1.1262426155137177 0.9940380651733244 0.13348929584878455 0.1363771110893336 1279.0213652968866 1031360.4685157366 0.054270417353104596 0.042090170594715245 9.311182101128372e-08 7.0309951796623045 -0.13220455034039336 YLAEVAAGDDKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YLAEVAAGDDKK 12 1 P63104;E7EX29;B0AZS6;P63104-2;B7Z2E6;H0YB80 P63104 YWHAZ 14-3-3 protein zeta/delta 0 ; 78.324 0.010503 22707900.0 63984.0 61079.0 59207.0 89580.0 75867.0 64023.0 80491.0 78456.0 68157.0 54199.0 False True 74815.22745839553 67142.51946295156 60618.71942379786 84561.12302227845 61001.40596581637 60665.52117394987 72866.30977562467 76396.61313100318 69153.66718462427 64024.84966095205 1.1685342153021 1.0486946836815603 0.9467998713750742 1.3207547299224853 0.9527770278080068 0.9475308648939945 1.1380941956364314 1.1932337761910672 1.0801066703136706 1.0 15.966344339732153 -10.622360907042198 3.4006014704632728 0.9999253447921368 1.0863959784599513 0.04976495070385978 0.11569066290881135 20368712.514003623 32450095.91627219 16950.213766469114 0.029581220218013324 2.3858277902244038e-11 10.622360907042198 0.08647063366781449 YLAEVAAGDDKK ddPTM_PC-9_Lapatinib_30min_R1 2 YLAEVAAGDDKK 12 1 P63104;E7EX29;B0AZS6;P63104-2;B7Z2E6;H0YB80 P63104 YWHAZ 14-3-3 protein zeta/delta 0 ; 149.41 0.00010214 44740000.0 138911.0 123766.0 149320.0 129124.0 137904.0 106373.0 129856.0 119974.0 134715.0 125188.0 False True 136930.10366684254 123479.42743116058 137043.48599186874 138620.2097050369 129792.7578496955 101823.6747575742 136579.3082897122 125548.43002662004 119541.97808816012 146826.5789974753 0.9325975215236546 0.8409882480016362 0.9333697408711349 0.9441084213194157 0.8839868008634002 0.6934962011157739 0.9302083398133297 0.8550797197881922 0.8141712413677884 1.0 17.163753627338238 -4.739270915106145 23.09393475965102 0.8727023627701463 0.9325981305411579 0.0378473021223138 0.08079319719665515 2457.1303166756966 2559356.9167723088 0.020018436249461313 0.8510159920862806 1.822758301701275e-05 4.739270915106145 0.05989576777101158 YLAEVACGDDR ddPTM_PC-9_AZD4547_30min_R2 2 YLAEVACGDDR 11 0 P27348;E9PG15 P27348 YWHAQ 14-3-3 protein theta 0 ; 144.65 0.00037891 15606600.0 43917.0 41825.0 43154.0 64991.0 66845.0 58637.0 56848.0 74583.0 46793.0 55715.0 False True 57881.69246965284 55344.11331754681 42581.74976367731 50008.32905094059 57564.72557868865 54970.419120488456 61907.361870831555 63057.911096839634 49266.38245019719 53764.43480832614 1.0765795767407393 1.0293814770833607 0.7920059034468443 0.9301377244868969 1.070684101561019 1.022430893516536 1.1514556433362593 1.1728554633122317 0.9163377728387769 1.0 15.714364524587562 -6.2667613425046165 23.853854482647343 1.0674016896637557 0.9504072430222088 0.18990273954323533 0.09759110350278304 359.910141423404 1613170.690736402 0.031206898567052173 0.036493199387931795 5.410515648953918e-07 6.2667613425046165 -0.1169944466415469 YLAEVACGDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YLAEVACGDDR 11 0 P27348;E9PG15 P27348 YWHAQ 14-3-3 protein theta 0 100.02 0.019913999999999998 4176200.0 18912.0 18871.0 24603.0 32160.0 31658.0 22943.0 29050.0 27010.0 20687.0 23408.0 False True 22113.428070973616 20744.388165905773 25189.628827397097 30358.179464126784 25454.842158854513 21739.828691156814 26298.17369621321 26301.01611946057 20989.508239041028 27651.685102373962 0.7997135794474647 0.7502033995072807 0.9109617997651256 1.0978780986306134 0.9205530174603773 0.78620267121769 0.9510513951988933 0.9511541890516672 0.7590679613677154 1.0 14.755079780977285 -5.288564604734093 8.466934647375554 0.9228967799791633 0.7749410812437698 0.2894684246943653 0.09222033926645658 0.3359739755861954 98.62281164005898 0.02480703775795421 0.05311839067194252 5.145592565668983e-06 5.288564604734093 -0.1479556987353935 YLAEVACGDDR ddPTM_PC-9_Lapatinib_30min_R1 2 YLAEVACGDDR 11 0 P27348;E9PG15 P27348 YWHAQ 14-3-3 protein theta 0 ; 174.86 0.0016432000000000003 22602000.0 48965.0 67757.0 70396.0 75255.0 84182.0 76917.0 61051.0 54495.0 82763.0 55705.0 False True 48266.750120918725 67600.11282947756 64608.3126164183 80789.50374332076 79230.58026817978 73627.43921228453 64211.922055162744 57027.03664377833 73441.35940697324 65333.5350277532 0.7387745068503544 1.0346924102723285 0.9888996912377873 1.2365702193980777 1.2127092194616933 1.1269471211225315 0.9828325074999539 0.8728601111137438 1.1240989696298522 1.0 15.995536081878948 -4.535897697876351 1.9208873756192197 1.0739319002808603 0.41944791243317636 0.45960688573951747 0.10617625236440789 1.8840589455020595 4.113608068900758 0.03154111199378602 2.7552117735880977 2.911402845445691e-05 4.535897697876351 -0.6544839878476839 YLAEVATGDDK ddPTM_PC-9_Lapatinib_30min_R1 3 YLAEVATGDDK 11 0 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 ;; 222.28 5.2571999999999995e-74 15057300.0 90994.0 106707.0 108427.0 94699.0 102523.0 102290.0 107368.0 101863.0 105762.0 100175.0 False True 89696.40887374405 106459.92649755836 99512.55060032383 101663.48036660333 96492.79870797333 97915.29514963631 112926.98968434137 106595.92684916423 93849.96983676637 117490.11527520297 0.7634379169996017 0.9061181551162151 0.84698657727274 0.8652939026272284 0.8212843989637206 0.8333917701951727 0.9611616212974754 0.9072757022961401 0.7987903460383615 1.0 16.842179858943517 -7.234684616593545 24.72094720716302 0.9090799016836162 0.8431464120223471 0.28915252189148877 0.05877351191725226 964.5874476065278 891263.6747409955 0.02180487940020012 0.016884815507501084 5.825260929839433e-08 7.234684616593545 -0.0659334896612691 YLAEVATGDDKKR ddPTM_PC-9_AZD4547_30min_R2 1 YLAEVATGDDKKR 13 2 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 98.156 0.011464 15929000.0 110450.0 63226.0 106600.0 147500.0 144770.0 118040.0 98969.0 118100.0 85655.0 133830.0 False True 145570.80249728257 83662.56804818213 105186.41434879729 113496.1538522831 124671.18441209925 110658.94013988526 107777.04927164236 99850.3586680175 90182.54843185162 129144.65243468198 1.1271918716952567 0.6478206141016678 0.8144852486400693 0.8788296821634679 0.9653607955246517 0.8568604123647604 0.8345451959472593 0.7731668078050636 0.6983064860348254 1.0 16.978628380643862 -10.804514271234675 5.368391216244909 1.0000222636425444 0.8400226499817008 0.1182172187192656 0.12733509623821063 3.2922515132019365e-05 4.405338338378751e-06 0.119628766584972 0.02901020274050337 1.5685043546318406e-11 10.804514271234675 -0.1599996136608436 YLAEVATGEKR ddPTM_PC-9_AZD4547_30min_R2 1 YLAEVATGEKR 11 1 P61981 P61981 YWHAG 14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed 0 68.786 0.022997 4913700.0 21452.0 13649.0 19230.0 38997.0 37496.0 26784.0 28646.0 23145.0 20463.0 20764.0 False True 28273.28977068089 18060.77232925755 18974.997635341206 30006.84414764399 32290.327628072588 25109.19224590552 31195.438505344802 19568.47206918942 21544.63240395752 20037.058680069727 1.4110499061822632 0.9013684402303053 0.9469951622298276 1.4975673139836096 1.6115303220722124 1.2531376309678075 1.5568871161900617 0.9766140021665757 1.0752392727874442 1.0 14.290383124653594 -7.7974126326876085 24.998875649662278 1.019444579324494 1.2979312278766786 0.26266487310272546 0.22490073421874532 294.79230508189175 204856.1242321802 0.13510699448335792 0.06490677689813854 1.5943635876456695e-08 7.7974126326876085 0.27848664855218463 YLAEVATGEKR ddPTM_PC-9_Lapatinib_30min_R1 1 YLAEVATGEKR 11 1 P61981 P61981 YWHAG 14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed 0 99.34299999999999 0.0029116 5386900.0 26146.0 20495.0 19531.0 15930.0 13014.0 25548.0 12282.0 8976.5 16495.0 10832.0 False True 25773.153245410827 20447.545086709044 17925.236571840247 17101.54534092219 12248.542106508425 24455.371595296798 12917.901863712457 9393.580960324363 14637.159399949533 12704.296767267255 2.0286957804556023 1.6094983816335544 1.4109585835577136 1.3461229420415057 0.9641259434419789 1.9249685396445007 1.0168136104153012 0.7394018836624643 1.1521424340198285 1.0 13.63302889831299 -1.522878745282251 0.2933847085105544 0.9857541053918226 9.04482867503919 0.5131986418364156 0.28317421061309095 46.53327073712882 0.6614458506038925 0.30865839766572006 195.3191526089679 0.029999999999867827 1.522878745282251 8.059074569647366 YLAFLR ddPTM_PC-9_AZD4547_30min_R2 1 YLAFLR 6 0 P40429;M0QYS1 P40429 RPL13A 60S ribosomal protein L13a 0 142.14 0.0076337 2389700.0 11343.0 11750.0 14483.0 20230.0 17766.0 14049.0 12757.0 13145.0 12023.0 14148.0 False True 14949.83805094319 15547.957716226549 14290.945956975915 15566.286050384335 15299.497563482431 13170.513809092245 13892.348286416365 11113.742292049896 12658.511234559026 13652.682826316042 1.095011012936361 1.1388206929012732 1.0467500152738916 1.1401631641496683 1.120622060741944 0.9646832037806958 1.01755445894036 0.8140335810502939 0.9271812284512525 1.0 13.736896855962684 -7.018206522980521 1.6842903197083032 0.915233736128666 1.1094129339871037 0.6511231000424467 0.058801725431456744 0.212005422800108 1.210640035703501 0.027449671073951628 0.020450259259323176 9.589445097307373e-08 7.018206522980521 0.19417919785843774 YLAFLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YLAFLR 6 0 P40429;M0QYS1 P40429 RPL13A 60S ribosomal protein L13a 0 142.14 0.0076337 2298100.0 19155.0 15997.0 17323.0 20480.0 20617.0 17415.0 18332.0 19025.0 16783.0 14424.0 False True 22397.563171504866 17585.07643951007 17736.046017843342 19332.571997055846 16577.246850372856 16501.72674264464 16595.46024781343 18525.613908653755 17028.419624683407 17038.957019678834 1.314491441326908 1.0320512235109525 1.0409114828659651 1.134610057101972 0.9729026742204506 0.9684704717305332 0.9739716009992163 1.0872504629982889 0.9993815704222239 1.0 14.05654940827114 -4.761145033847128 6.558066232980973 1.0247112597546018 1.3224332973397306 0.746531723346633 0.05091702264055436 0.06284251072596506 13.016740944198942 0.01331883865979206 0.08351047238306164 1.733225085768876e-05 4.761145033847128 0.29772203758512883 YLAFLR ddPTM_PC-9_Lapatinib_30min_R1 1 YLAFLR 6 0 P40429;M0QYS1 P40429 RPL13A 60S ribosomal protein L13a 0 142.14 0.0076337 4281900.0 17454.0 19114.0 20552.0 19140.0 22409.0 22097.0 15879.0 15776.0 18809.0 18828.0 False True 17205.102759328416 19069.74270736065 18862.293893014215 20547.619449168287 21090.946677789114 21151.962820622863 16701.136923456295 16509.010553119504 16690.532352449263 22082.394713266985 0.7791321087559259 0.8635722237092179 0.8541779158436041 0.9304977886670682 0.955102331592587 0.9578654441818701 0.7563100442825769 0.7476096124303483 0.7558298168822098 1.0 14.430609012427247 -10.52981504373642 9.413861121883514 1.0000000000420557 0.8489831535218748 0.25698700342344993 0.07900804264924383 1.2223978669582423e-10 0.0 0.0863800023850382 0.020950227713003814 2.9524663480490925e-11 10.52981504373642 -0.15101684652018088 YLAPSGPSGT(ph)LK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YLAPSGPSGTLK 12 0 Q16658 Q16658 FSCN1 Fascin 1 YLAPS(0.012)GPS(0.021)GT(0.966)LK 108.72 0.0015859000000000001 0.0 34938.0 37241.0 31577.0 41097.0 42489.0 32487.0 38727.0 38391.0 33722.0 27500.0 True False 40852.313343045505 40938.04036280519 32329.915436439365 38794.46832827169 34163.58545983858 30783.324529905018 35058.49820080029 37383.27692862687 34215.12045424381 32485.532310119786 1.2575540690869125 1.2601929982859572 0.9952096560341126 1.1942075616284902 1.051655399508293 0.9476010500931671 1.0792034394301424 1.1507669497840227 1.053241797844428 1.0 14.987509725025545 -5.248308341478821 24.77446534829191 1.0656818568660313 1.2588735802288236 0.5722385633732421 0.06893450555145955 513.0930870935468 968053.0081408758 0.01790007080358871 0.046721929197485995 5.645360218023667e-06 5.248308341478821 0.19319172336279222 YLAPSGPSGT(ph)LK ddPTM_PC-9_Lapatinib_30min_R1 1 YLAPSGPSGTLK 12 0 Q16658 Q16658 FSCN1 Fascin 1 Y(0.002)LAPS(0.004)GPS(0.021)GT(0.973)LK 104.9 0.0045347 6510800.0 48182.0 46539.0 47199.0 44132.0 35567.0 35136.0 30069.0 33331.0 39471.0 27338.0 True False 47494.91584450336 46431.24180484764 43318.480413408826 47377.61450003628 33475.01898741243 33633.31518601644 31625.82569125303 34879.67994079778 35025.360331943484 32063.33687440475 1.4812842478169264 1.4481100949262826 1.3510284529364982 1.4776258218419083 1.0440279225626883 1.0489649071074996 0.9863547831947281 1.0878368673050134 1.0923803866435136 1.0 14.968636956060083 -6.26527668660481 24.998117932928636 1.045092543027619 1.4338060368408043 0.9476856353557509 0.04560033411012904 69.51385303756544 452847.1917132162 0.014200977680985888 0.016711506517786467 5.429043399467227e-07 6.26527668660481 0.3887134938131853 YLCEGTES(ph)PYQTGQLHPAIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YLCEGTESPYQTGQLHPAIR 20 0 H0Y6V4;A0A0G2JQF6;H0Y6P5;Q5TG12;E9PGC5;Q15262;Q15262-2;Q15262-3;Q15262-4 H0Y6V4 PTPRK Protein-tyrosine-phosphatase;Receptor-type tyrosine-protein phosphatase kappa 1 YLCEGT(0.017)ES(0.981)PY(0.002)QTGQLHPAIR 132.48 2.5123000000000003e-05 4919400.0 9277.0 8493.4 11882.0 10315.0 19079.0 13109.0 9232.2 8739.5 8312.0 6948.3 True False 10847.412870897962 9336.568621074885 12165.311942735929 9737.083991681213 15340.606909747472 12421.540962924399 8357.659180660221 8510.09738526567 8433.547275240924 8207.971787287468 1.3215704381073128 1.1375000868710818 1.4821337424158305 1.1862959868797354 1.868988747440269 1.5133508356062968 1.0182368308824585 1.0368088007376115 1.027482488219907 1.0 13.00281005673639 -7.269665376092081 24.368714464301267 1.0236993844052455 1.4183835502454825 0.5138596010781721 0.18948312425778996 402.195205406187 1191457.8115734418 0.08346614448429686 0.0574013880796147 5.374457388321019e-08 7.269665376092081 0.3946841658402369 YLDEDTIYHLQPSGR ddPTM_PC-9_AZD4547_30min_R2 2 YLDEDTIYHLQPSGR 15 0 P31153-2;P31153 P31153-2;P31153 MAT2A S-adenosylmethionine synthase isoform type-2 0 ; 108.36 0.00062373 10786700.0 35115.0 28921.0 54261.0 74070.0 59176.0 53951.0 38814.0 52215.0 48324.0 49802.0 False True 46280.83956262631 38269.14766902023 53541.463686492396 56994.30587009229 50960.433852112845 50577.435441265276 42268.370807318715 44146.371531334 50878.3079845987 48058.44713854906 0.963011547776439 0.7963042908709268 1.1140905891556627 1.1859373172375252 1.060384529387676 1.0524150997940935 0.8795201119474799 0.9185975444454785 1.0586756546236333 1.0 15.552502412501033 -10.33707301748256 14.860027461243249 0.999999993532128 1.0027664570163903 6.173738220416336e-05 0.1101528216050854 0.0 0.0 0.11653240959107805 0.028263260797162088 4.60179197623897e-11 10.33707301748256 0.0027664634842623492 YLDEDTIYHLQPSGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YLDEDTIYHLQPSGR 15 0 P31153-2;P31153 P31153-2;P31153 MAT2A S-adenosylmethionine synthase isoform type-2 0 ; 65.374 0.028567000000000002 7550200.0 23475.0 36822.0 33082.0 44609.0 38162.0 38317.0 41829.0 37628.0 38863.0 32071.0 False True 27448.853847615588 40477.44481187976 33870.80034418366 42109.702354329325 30684.430048209182 36307.5890667766 37866.6543042651 36640.304870161526 39431.297853427364 37885.21842610369 0.7245267412448853 1.0684231606274697 0.8940373515398816 1.111507445482085 0.8099314540857175 0.9583576543869133 0.9995099903706561 0.9671398606722987 1.0408095687857615 1.0 15.209347445280013 -4.74843206919585 24.999110024300933 0.9778010340988963 0.7245261370960193 0.4734962859119165 0.08167753804803682 557.8565067822238 1072096.7657984751 0.01916441465279877 0.35063185534438707 1.784711124899945e-05 4.74843206919585 -0.253274897002877 YLDEDTIYHLQPSGR ddPTM_PC-9_Lapatinib_30min_R1 4 YLDEDTIYHLQPSGR 15 0 P31153-2;P31153 P31153-2;P31153 MAT2A S-adenosylmethionine synthase isoform type-2 0 ;;; 145.86 4.6549e-05 25931400.0 130829.0 115417.0 136699.0 109433.0 133456.0 136145.0 109639.0 106550.0 137852.0 110544.0 False True 128963.35446890001 115149.75902769959 125460.1358933995 117481.06787778635 125606.38046459112 130322.39571949598 115315.57095225295 111500.70197989864 122325.65611408559 129651.38310937863 0.9946932410285344 0.8881490984986644 0.9676729463622981 0.9061304635576085 0.9688009294789011 1.0051755144760104 0.8894280044430265 0.860003952953071 0.9434967308515885 1.0 16.984278071251993 -7.300715822670365 24.99480313288095 0.9115658388722994 0.9510282369149404 0.07122957142700803 0.04836317900710365 1142.6965506085976 727186.0938497552 0.019692949686436343 0.013277255367104713 5.003618358879404e-08 7.300715822670365 0.03946239804264107 YLDIHER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YLDIHER 7 0 P62072 P62072 TIMM10 Mitochondrial import inner membrane translocase subunit Tim10 0 77.923 0.024411000000000002 2258400.0 9921.1 8613.2 11747.0 12567.0 14322.0 13005.0 12791.0 13324.0 11530.0 10237.0 False True 11600.546279343089 9468.261573344262 12027.093030745582 11862.91173276372 11515.706911337245 12322.994906005943 11579.343881179444 12974.259117944935 11698.604437383048 12092.887063952581 0.9592867458361453 0.7829612170585792 0.994559278288216 0.9809825949773078 0.952271103702288 1.0190283627752785 0.9575334508577404 1.0728835098956324 0.9673954925333884 1.0 13.56187109523755 -5.293453697706177 24.16082487515372 0.9934521817077387 0.8711239915687364 0.4743214332071177 0.05135504177432029 293.6401315482503 221606.2243379937 0.012491150528091962 0.02600680380631018 5.0879906235064366e-06 5.293453697706177 -0.12232819013900231 YLGINS(ph)DGLVVGRSDAIGPR ddPTM_PC-9_AZD4547_30min_R2 1 YLGINSDGLVVGRSDAIGPR 20 1 E9PRR7;Q14331 E9PRR7 FRG1 Protein FRG1 1 Y(0.006)LGINS(0.994)DGLVVGRSDAIGPR 60.99100000000001 0.005949899999999999 35229000.0 1604.9 3420.0 55297.0 94932.0 71421.0 33200.0 10758.0 75404.0 17697.0 31764.0 True False 2115.2248160062345 4525.448118254878 54563.72564958208 73046.89408477931 61505.42696619834 31123.998751645137 11715.441158992506 63752.04441154277 18632.427290858435 30651.952028209154 0.06900783395653177 0.1476398016703825 1.7801060630450807 2.383107412459535 2.006574553868366 1.015400217349993 0.3822086485131754 2.079868986904045 0.6078708225078426 1.0 14.90369133247832 -5.251039492024536 23.501412389389504 1.4511631980561437 0.10832318443685651 0.40560940827335423 0.6269618296031305 311.8590246289358 704722.0329115093 0.16850437383545744 0.4340764250477209 5.609969601573366e-06 5.251039492024536 -1.3428400136192873 YLGPS(ph)NSQVDFLLR ddPTM_PC-9_AZD4547_30min_R2 1 YLGPSNSQVDFLLR 14 0 H7BYZ6 H7BYZ6 GPR75-ASB3 1 YLGPS(0.92)NS(0.08)QVDFLLR 96.14299999999999 0.0030228 31343000.0 61021.0 43571.0 49851.0 77383.0 61826.0 47069.0 33752.0 38886.0 23226.0 32165.0 True False 80424.4086843519 57654.47367265591 49189.94316793522 59543.54490543203 53242.527094442456 44125.7679891923 36755.86261371211 32877.06221138474 24453.678943181236 31038.913140264034 2.5910832741119547 1.857490093551822 1.5847830413921762 1.9183514782349598 1.7153476622664225 1.4216273549846645 1.1841865224988173 1.0592207936796678 0.7878394076711289 1.0 14.921790420495766 -5.3341999834165925 0.2985021455634208 0.7909797920104509 3.137955057594203 0.8343797931929341 0.20762152047891333 2.387439650885148 0.22602475175611267 0.26922539499406667 1.9951788106245403 4.6323356136639375e-06 5.3341999834165925 2.346975265583752 up YLGPS(ph)NSQVDFLLR ddPTM_PC-9_Lapatinib_30min_R1 2 YLGPSNSQVDFLLR 14 0 H7BYZ6 H7BYZ6 GPR75-ASB3 1 YLGPS(0.5)NS(0.5)QVDFLLR;YLGPS(0.5)NS(0.5)QVDFLLR 98.04799999999999 0.0025502 100837000.0 60935.0 42710.0 63355.0 39810.0 34283.0 46439.0 51130.0 52806.0 53736.0 26548.0 True False 60066.05572588959 42611.107619094575 58146.196457372265 42737.760202266945 32266.54134297129 44452.91222459636 53777.2612189886 55259.559537780704 47683.6858148341 31136.786427013576 1.9291026023731734 1.3685133409312316 1.867443725885788 1.3725809599024204 1.036283606807206 1.4276653863685178 1.7271294629278973 1.7747354778346283 1.5314260489471965 1.0 14.926332433630813 -11.627092564878597 2.1525888198000738 0.07909192422280419 1.5493821924284938 0.2952654198592807 0.2588645792974676 5002166.71328807 1312561.9395887584 22543397.739284977 0.06991353944332684 2.3599751779801567e-12 11.627092564878597 1.4702902682056898 YLGPSNS(ph)QVDFLLR ddPTM_PC-9_AZD4547_30min_R2 1 YLGPSNSQVDFLLR 14 0 H7BYZ6 H7BYZ6 GPR75-ASB3 1 YLGPS(0.005)NS(0.995)QVDFLLR 82.831 0.0087815 81978000.0 110750.0 69982.0 90186.0 137760.0 102910.0 100450.0 72089.0 47327.0 54232.0 58370.0 True False 145966.19625689476 92602.31292740146 88990.07471351446 106001.56037078334 88622.72285590312 94168.84562056478 78504.7813451024 40013.699616268204 57098.59280317764 56326.484066445235 2.591430988035868 1.6440279286412347 1.5798975595305718 1.8819133153374026 1.5733757276836204 1.6718395827703183 1.3937454582198785 0.7103887323956926 1.0137077388999036 1.0 15.781525800031366 -7.384327175449815 1.4497720318626566 0.8776971378869898 1.8398431229439252 0.6643542728754573 0.29083178852076647 0.2611603292264317 1.0598008463144213 0.18643661994308142 0.09909357366769601 4.1273645011814646e-08 7.384327175449815 0.9621459850569354 YLGPSNS(ph)QVDFLLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YLGPSNSQVDFLLR 14 0 H7BYZ6 H7BYZ6 GPR75-ASB3 1 YLGPS(0.077)NS(0.923)QVDFLLR 81.33800000000001 0.010537999999999999 3700900.0 9648.6 13362.0 9017.0 12882.0 10239.0 13865.0 10838.0 7865.3 11371.0 14006.0 True False 11281.917411463415 14688.491053618402 9231.999477162934 12160.263304007494 8232.741451276504 13137.894992062473 9811.346179675 7658.844208974204 11537.279363181486 16545.17692856501 0.6818855706514293 0.8877808389137822 0.5579873528716407 0.7349733010719863 0.49759162363883785 0.794061922020313 0.5930034004493389 0.46290494456733905 0.6973197937377471 1.0 14.014123098978597 -8.559638640969192 22.370584120933717 1.0000000023849862 0.651755943008631 0.4102400716461826 0.12468657226480911 4561.129102877141 2775713.7457250943 0.12004836069107849 0.03099635335574637 2.756521340319398e-09 8.559638640969192 -0.34824405937635516 YLGPSNS(ph)QVDFLLR ddPTM_PC-9_Lapatinib_30min_R1 1 YLGPSNSQVDFLLR 14 0 H7BYZ6 H7BYZ6 GPR75-ASB3 1 YLGPS(0.004)NS(0.996)QVDFLLR 85.807 0.0067491 28270000.0 57081.0 39195.0 57642.0 37196.0 33596.0 43743.0 38222.0 51311.0 41784.0 25375.0 True False 56267.01447262659 39104.2463856336 52902.897264554565 39931.51792221857 31619.949332277345 41872.21385991337 40200.948138317675 53695.096380014846 37077.845914973695 29761.034939937843 1.8906269417774524 1.313941079823055 1.7775892999460674 1.3417382158519104 1.0624613490791253 1.4069475051663247 1.3507913356994847 1.8042079681832124 1.2458520340371986 1.0 14.861137076585257 -1.5229048814713366 0.03457111832562324 1.244016691515643e-07 3.612009752803075 0.2806262212063201 0.24784060632497407 1715.4432072567536 4.551005694029036 141.6019073173189 391.65752831742867 0.029998194630211385 1.5229048814713366 3.612009628401406 YLGS(ph)PITTVPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YLGSPITTVPK 11 0 D6RJC2;P30307-4;P30307-3;P30307-2;P30307;A0A3B3IT42 D6RJC2 CDC25C M-phase inducer phosphatase 3 1 YLGS(0.996)PIT(0.004)TVPK;YLGS(1)PITTVPK;YLGS(0.997)PIT(0.002)TVPK;YLGS(0.996)PIT(0.004)TVPK 152.38 0.00019553 89370900.0 549529.0 511273.0 484667.0 555852.0 836989.0 792783.0 999420.0 833327.0 856250.0 734822.0 True False 642553.4060075126 562028.8045544571 496223.29938983236 524709.4145364987 672987.0138258111 751208.0638652914 904747.7024257946 811453.0492329401 868771.036384149 868039.4117522498 0.7402352903659472 0.6474692242601395 0.5716598724338351 0.6044764873950883 0.7752954586097649 0.8654077841337651 1.0422887373275418 0.9348112980203481 1.0008428472509356 1.0 19.727401021540565 -6.735323987364351 1.8609629842123947 0.9881179401655426 0.6377380826987606 0.9001022343000491 0.052506959370581766 0.10075072600444906 0.7201147652283222 0.02207252155932644 0.02059194443442652 1.8393992820482693e-07 6.735323987364351 -0.3503798574667819 YLHDESGLNR ddPTM_PC-9_Lapatinib_30min_R1 1 YLHDESGLNR 10 0 Q15019-2;Q15019-3;Q15019;B5MCX3;C9J2Q4;C9J938;C9JB25;H7C310;C9IY94 Q15019-2 SEPT2 Septin-2 0 68.626 0.038133 0.0 17567.0 18422.0 22429.0 15693.0 19605.0 18969.0 19005.0 16837.0 19508.0 16688.0 False True 17316.491358606738 18379.344990844307 20584.97419844375 16847.115570313355 18451.87244491301 18157.74008889872 19988.985907820806 17619.308486490438 17310.80361165296 19572.498564637743 0.8847358604431319 0.9390392815790446 1.0517295035410186 0.8607544670230083 0.9427448613152843 0.9277170223787825 1.021279211839389 0.9002074225885398 0.8844452615226622 1.0 14.256540317257759 YLHDESGLNRR ddPTM_PC-9_AZD4547_30min_R2 2 YLHDESGLNRR 11 1 Q15019-2;Q15019-3;Q15019;B5MCX3;C9J2Q4;C9J938;C9JB25;H7C310;C9IY94 Q15019-2 SEPT2 Septin-2 0 ; 89.029 0.0037717 22707500.0 16491.0 13462.9 30755.0 33739.0 33319.0 22356.6 24880.0 36390.0 25875.0 25690.0 False True 21734.794965891222 17814.51914364139 30347.168605039966 25960.99481235377 28693.231977804287 20958.6382678021 27094.27180105349 30766.761659010717 27242.69967514056 24790.60091942742 0.8767353012753523 0.7185997306616659 1.2241400966306581 1.0472111949496616 1.157423818448811 0.8454267944500546 1.0929251730973886 1.2410655860665327 1.0989124371645032 1.0 14.597505622049944 -5.254735980890196 24.991389737079455 1.089477424855423 0.7976674994929647 0.5143255647898535 0.11299886875842148 414.0432420888776 1543612.3086696863 0.029242310014269707 0.07371330588169844 5.562423089261015e-06 5.254735980890196 -0.2918099253624584 YLHDESGLNRR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YLHDESGLNRR 11 1 Q15019-2;Q15019-3;Q15019;B5MCX3;C9J2Q4;C9J938;C9JB25;H7C310;C9IY94 Q15019-2 SEPT2 Septin-2 0 56.013000000000005 0.03269 1610400.0 3067.4 2982.2 4442.0 5033.3 5368.5 5305.1 5469.8 5708.8 5571.1 3426.0 False True 3586.6502360884356 3278.253107326809 4547.9141263788115 4751.300519178774 4316.580963099705 5026.891216905196 4951.660946077348 5558.95004897359 5652.56679801428 4047.1066797989242 0.8862257706205644 0.8100238927948609 1.1237445627711422 1.1739993271970872 1.0665844279929306 1.2420950606508232 1.2235064054015412 1.3735615314320748 1.3966933034478648 1.0 11.982675162922797 -5.297104450867564 0.681179121513929 1.267884328068742 0.6998940210462697 0.5687325492157321 0.12045961904050675 1.2310237271759177 0.680127375170844 0.05858138380287805 0.488858840179088 5.045399375780332e-06 5.297104450867564 -0.5679903070224722 YLHDESGLNRR ddPTM_PC-9_Lapatinib_30min_R1 2 YLHDESGLNRR 11 1 Q15019-2;Q15019-3;Q15019;B5MCX3;C9J2Q4;C9J938;C9JB25;H7C310;C9IY94 Q15019-2 SEPT2 Septin-2 0 ; 109.83 0.00079838 16316400.0 22174.0 20443.3 25150.0 27962.0 17121.199999999997 25615.0 15395.5 19374.4 27600.0 20173.9 False True 21857.794693786433 20395.964794882613 23082.264081807487 30018.418758497577 16114.16467757431 24519.50616148142 16192.603659239961 20274.605353724543 24491.39735911531 23660.931734967962 0.9237926442889519 0.8620102125876925 0.9755433277251176 1.2686913218271125 0.6810452292442714 1.0362865856734031 0.6843603557382009 0.8568811059862514 1.0350986019253006 1.0 14.530219265693372 -6.289760340945471 24.999994717535348 0.8729272285013214 0.994833483395818 0.13199948700456643 0.15486319432844897 1567.2892416809357 1383501.6196919903 0.04783621844551559 0.05425190385571958 5.13144477144314e-07 6.289760340945471 0.12190625489449658 YLIPNATQPESK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YLIPNATQPESK 12 0 P31946-2;P31946 P31946-2 YWHAB 14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed 0 120.86 0.002578 0.0 25952.0 23402.0 25176.0 27382.0 29053.0 27714.0 29966.0 21297.0 24358.0 23418.0 False True 30345.161024635556 25725.19590156997 25776.291320511697 25847.87531364177 23360.273208705563 26260.629052291322 27127.403544947476 20737.976316036722 24714.189669191346 27663.498023214004 1.096938680682075 0.9299328624305756 0.9317798963414299 0.9343675659510361 0.8444439379684607 0.9492880846180243 0.9806208716693506 0.7496512660341912 0.8933862828356802 1.0 14.755695974998906 YLKGDHAGVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YLKGDHAGVLK 11 1 Q16658 Q16658 FSCN1 Fascin 0 58.592 0.032181 4979900.0 74091.0 60848.0 73115.0 91169.0 93292.0 89670.0 90490.0 96337.0 87977.0 77627.0 False True 86633.14293604624 66888.58730957731 74858.33889018153 86061.09650388581 75012.10230222551 84967.54734498668 81918.1321091337 93808.25582748867 89263.49718886812 91700.1606050062 0.9447436336476456 0.7294271555062648 0.8163381437534231 0.9385054064909398 0.8180149501082812 0.9265801366584306 0.8933259393295058 1.0229890025118167 0.9734279264064336 1.0 16.484636640129246 -7.3158598527716405 0.8623955665704859 1.007969092491782 0.8373941599557548 0.4755477826798806 0.06361687256896803 0.5108040642183738 0.7311119681301996 0.050082137300205255 0.028293881560885314 4.832147107136302e-08 7.3158598527716405 -0.17057493253602707 YLKGDHAGVLK ddPTM_PC-9_Lapatinib_30min_R1 1 YLKGDHAGVLK 11 1 Q16658 Q16658 FSCN1 Fascin 0 57.348 0.034564 5942900.0 195050.0 143430.0 155750.0 137680.0 158790.0 151820.0 129170.0 121670.0 156940.0 130450.0 False True 192268.55123221048 143097.8966473126 142944.836212386 147805.44648701596 149450.28439315152 145327.01250970553 135857.79056633596 127323.23237817275 139263.76454853485 152998.10868630096 1.2566727319906124 0.9352919318807579 0.9342915245146746 0.966060611834544 0.9768113192796147 0.9498614967043558 0.8879703921366205 0.8321882765180413 0.910231935180805 1.0 17.22315429333017 -4.7613466722551285 6.99417201448965 0.9284700819793641 1.2637262049032263 0.8209626627271456 0.04538832469481834 0.04752211923135689 13.408816753385235 0.012413483681806389 0.07562114518452148 1.732420554182475e-05 4.7613466722551285 0.3352561229238622 YLLGDAPVS(ph)PSSQK ddPTM_PC-9_AZD4547_30min_R2 1 YLLGDAPVSPSSQK 14 0 Q9NYB0;A0A590UJT3;H3BMI8 Q9NYB0 TERF2IP Telomeric repeat-binding factor 2-interacting protein 1 1 Y(0.002)LLGDAPVS(0.932)PS(0.053)S(0.013)QK 88.78 0.0055823 72718000.0 91373.0 69827.0 106070.0 127150.0 114250.0 98165.0 86617.0 115840.0 92287.0 98627.0 True False 120427.7133235327 92397.21220859163 104663.44249509317 97837.5319479173 98388.35959855166 92026.72703178473 94325.74520063723 97939.58973838417 97165.1024123555 95174.09874972224 1.2653412525630474 0.9708230855074033 1.099705107482288 1.0279848533706535 1.0337724327422517 0.9669303753932664 0.9910862980555676 1.0290571807350053 1.02091959565458 1.0 16.53828138281387 -4.7547661699622 24.999978886626373 1.0177929034455486 1.265341671117122 0.8115208269797594 0.03609501137841936 96.73561913087268 362369.9665087037 0.009140597898388402 0.08625890636137526 1.7588703587159554e-05 4.7547661699622 0.2475487676715733 YLLGDAPVS(ph)PSSQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YLLGDAPVSPSSQK 14 0 Q9NYB0;A0A590UJT3;H3BMI8 Q9NYB0 TERF2IP Telomeric repeat-binding factor 2-interacting protein 1 1 YLLGDAPVS(0.998)PS(0.002)SQK;YLLGDAPVS(0.997)PS(0.003)S(0.001)QK 188.92 3.2512e-06 92160000.0 220619.0 219524.0 239446.0 283400.0 286870.0 266409.0 273763.0 262619.0 248641.0 202033.0 True False 257965.4392761275 241316.89193642663 245155.30074401243 267522.01679519704 230659.88281352585 252438.0430537591 247830.18676751823 255725.52951783146 252276.90424244216 238659.9836076521 1.0808910458160963 1.011132609198291 1.0272157780209956 1.1209336929939333 0.9664790859649177 1.0577309159157473 1.038423714865168 1.071505686257963 1.057055734392305 1.0 17.86459716280676 -10.67717751287739 5.230938781109357 0.9999982403355456 1.0466919492204056 0.11585817090956896 0.039588708162118354 7.759803189764608e-07 1.2547285052599408e-07 0.036612323921764334 0.008879458234800236 2.1029187202237446e-11 10.67717751287739 0.04669370888486002 YLLGDAPVS(ph)PSSQK ddPTM_PC-9_Lapatinib_30min_R1 4 YLLGDAPVSPSSQK 14 0 Q9NYB0;A0A590UJT3;H3BMI8 Q9NYB0 TERF2IP Telomeric repeat-binding factor 2-interacting protein 1 1 Y(0.026)LLGDAPVS(0.906)PS(0.053)S(0.015)QK;YLLGDAPVS(0.48)PS(0.405)S(0.114)QK;YLLGDAPVS(0.895)PS(0.04)S(0.065)QK;Y(0.041)LLGDAPVS(0.941)PS(0.014)S(0.004)QK 116.58 0.00014244 182333000.0 674191.0 572668.0 649061.0 586906.0 657106.0 569944.0 520942.0 516928.0 628491.0 497204.0 True False 664576.9127085124 571342.0224306161 595697.7100279136 630069.025101023 618456.3170001024 545568.8237243555 547913.8277712183 540946.3620184434 557703.7252763672 583145.0489173157 1.1396425536706272 0.9797597072827533 1.0215257955699075 1.0804670746512002 1.0605531473659027 0.9355628153531865 0.9395841202604588 0.9276360367335372 0.9563722204480967 1.0 19.153495252075565 -6.760790651886546 24.99970445128076 0.946542847794314 1.0515332006194014 0.5978086575520778 0.04267833882496805 12.251519595485906 472139.53962330526 0.014305280240652972 0.013494428996461192 1.7346399653020624e-07 6.760790651886546 0.1049903528250874 YLLSQS(ph)SPAPLTAAEEELR ddPTM_PC-9_AZD4547_30min_R2 2 YLLSQSSPAPLTAAEEELR 19 0 F8VS81;Q12792-4;Q12792;Q12792-3 F8VS81 TWF1 Twinfilin-1 1 YLLSQS(0.909)S(0.091)PAPLTAAEEELR;YLLS(0.002)QS(0.499)S(0.499)PAPLTAAEEELR 258.68 1.0560999999999998e-65 25603800.0 60684.0 61570.0 88928.0 126728.0 84083.0 103547.0 75315.0 96027.0 78446.0 82302.0 True False 79980.24969438737 81471.29843302697 87748.75661547708 97512.81752808244 72409.52682822764 97072.18972098206 82017.88909551228 81188.23363093764 82592.49540931694 79420.63203077903 1.0070462504427244 1.0258203233821308 1.1048609709057784 1.227802084101923 0.9117218659273036 1.2222540571493092 1.0327025484225143 1.0222562016312535 1.03993752375716 1.0 16.277226221449887 -7.491642883587802 24.99886830830913 1.0241538976876998 1.084319932781252 0.09669759137540412 0.08947320185389823 1675.9388598956534 1341300.5169291685 0.036713499714035085 0.02472281021777298 3.223718536207666e-08 7.491642883587802 0.06016603509355223 YLLSQS(ph)SPAPLTAAEEELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YLLSQSSPAPLTAAEEELR 19 0 F8VS81;Q12792-4;Q12792;Q12792-3 F8VS81 TWF1 Twinfilin-1 1 YLLS(0.005)QS(0.892)S(0.103)PAPLTAAEEELR;YLLSQS(0.711)S(0.289)PAPLTAAEEELR 231.37 7.0845e-36 16569600.0 17055.4 15460.2 21602.5 19577.3 25832.8 21361.2 25753.6 24991.7 24525.1 18961.9 True False 19942.542360495114 16994.98648309769 22117.585527937477 18480.447351462957 20771.048282306427 20240.981067756573 23314.032568082486 24335.69435589497 24883.7331905692 22399.5423676822 0.8903102587161773 0.7587202543752796 0.9874123839176497 0.8250368265615253 0.9272978858833587 0.9036336874881884 1.0408262894566855 1.0864371225282812 1.1109036417847162 1.0 14.451181637251091 -7.240713630009753 2.0167883384743166 1.0767575753170817 0.8734486978301259 0.6625542746992197 0.06229263531467861 0.1920605149650587 1.5266615155341496 0.030064623205003176 0.01949023643511729 5.744951544302799e-08 7.240713630009753 -0.2033088774869558 YLLSQS(ph)SPAPLTAAEEELR ddPTM_PC-9_Lapatinib_30min_R1 2 YLLSQSSPAPLTAAEEELR 19 0 F8VS81;Q12792-4;Q12792;Q12792-3 F8VS81 TWF1 Twinfilin-1 1 YLLS(0.061)QS(0.61)S(0.328)PAPLTAAEEELR;YLLS(0.005)QS(0.869)S(0.125)PAPLTAAEEELR 206.63 1.7698e-20 31912000.0 74389.0 61216.0 85113.0 64609.0 81054.0 86021.0 84587.0 67031.0 94802.0 68527.0 True False 73328.19921872819 61074.25811309981 78115.33768568095 69360.56138930593 76286.56307829518 82342.08235474504 88966.50097263034 70145.5049686962 84124.40045068292 80371.8006435121 0.9123622792025563 0.7598966008487696 0.9719246932411075 0.8629962354203515 0.9491707597377725 1.0245145896378767 1.1069367646401242 0.8727626407155604 1.0466905031009 1.0 16.29440178383941 -6.4723384483535344 3.070371950581011 1.0078442266534213 0.8750171440528562 0.41941149438369507 0.07371693756862302 0.2623290506570678 4.9241901841260525 0.024558827596542827 0.027007028371867695 3.370245609841815e-07 6.4723384483535344 -0.13282708260056508 YLLSQSS(ph)PAPLTAAEEELR ddPTM_PC-9_AZD4547_30min_R2 3 YLLSQSSPAPLTAAEEELR 19 0 F8VS81;Q12792-4;Q12792;Q12792-3 F8VS81 TWF1 Twinfilin-1 1 YLLSQS(0.001)S(0.997)PAPLT(0.001)AAEEELR;YLLSQS(0.006)S(0.994)PAPLTAAEEELR;YLLS(0.005)QS(0.257)S(0.718)PAPLT(0.02)AAEEELR 198.67 5.341e-15 25345500.0 65630.09999999999 56598.5 78335.0 116765.8 96821.09999999999 70793.6 59249.5 123836.1 84004.6 80342.3 True False 86499.10660911647 74892.85828100839 77296.2267168202 89847.24882362665 83379.16151883871 66366.8650007369 64522.590718509564 104700.07621548256 88444.9116572101 77529.54053129286 1.115692238292103 0.9659912565943785 0.9969906462378879 1.1588776124290592 1.0754502212635297 0.8560203574784448 0.8322323372014133 1.3504539753234188 1.1407898337990476 1.0 16.242458494552544 -7.76215066625195 24.99998396168526 1.1842163831332657 1.0021959387614026 0.2580520436560755 0.12563684107385342 24.849079349299252 873254.7454599993 0.06585743217826082 0.03458468986182132 1.729216352180144e-08 7.76215066625195 -0.18202044437186315 YLLSQSS(ph)PAPLTAAEEELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YLLSQSSPAPLTAAEEELR 19 0 F8VS81;Q12792-4;Q12792;Q12792-3 F8VS81 TWF1 Twinfilin-1 1 YLLS(0.002)QS(0.09)S(0.907)PAPLTAAEEELR;YLLSQS(0.174)S(0.826)PAPLTAAEEELR 170.16 4.6694e-08 15382700.0 36593.8 38929.7 45616.0 40272.0 54702.0 50595.0 59133.0 49522.0 44895.0 41564.0 True False 42788.40757950482 42794.383338575695 46703.65843964334 38015.69040358563 43983.53578159267 47941.7091325929 53531.49415415402 48222.099972896205 45551.50444200448 49099.224179557015 0.8714680994352703 0.8715898072457444 0.951209702801962 0.7742625477046512 0.8958091806246031 0.9764249829542916 1.0902716906154788 0.9821356809335083 0.9277438738221516 1.0 15.583412608139346 -6.761508297525605 3.8879078485311154 1.0022923655535687 0.8697661010163807 0.5617032779339659 0.054596757065296105 0.16621762817409974 5.538194041190235 0.019792190949121928 0.018483737952488907 1.7317759435406215e-07 6.761508297525605 -0.13252626453718797 YLLSQSS(ph)PAPLTAAEEELR ddPTM_PC-9_Lapatinib_30min_R1 2 YLLSQSSPAPLTAAEEELR 19 0 F8VS81;Q12792-4;Q12792;Q12792-3 F8VS81 TWF1 Twinfilin-1 1 YLLSQS(0.071)S(0.928)PAPLT(0.001)AAEEELR;YLLSQS(0.168)S(0.831)PAPLTAAEEELR 235.95 1.4179999999999999e-43 7214000.0 24281.4 22625.6 25365.4 22945.9 28008.6 23629.0 25460.9 20594.7 28901.2 24478.7 True False 23935.142783336592 22573.21181331272 23279.95472527552 24633.418031278496 26361.18921502627 22618.442751889295 26779.140820859528 21551.60494664873 25646.04251287188 28709.810679182516 0.8336921148940897 0.786254290059828 0.810871063742535 0.8580139488394533 0.9181944635441559 0.7878297424054395 0.9327522608944643 0.7506703958266016 0.8932849749325525 1.0 14.80925619657643 -14.522878745279957 0.24146704380192235 1.9173189202087275 0.8245467579743707 0.4325802643251574 0.055872399368449586 164.3340607213733 1.6346793543900642 74.10952404296141 0.08418615921290623 3.000000000002627e-15 14.522878745279957 -1.0927721622343567 YLMAS(ph)DPNLQVLGAAYIQHK ddPTM_PC-9_AZD4547_30min_R2 2 YLMASDPNLQVLGAAYIQHK 20 0 Q9Y446;Q9Y446-2;E9PKC4 Q9Y446 PKP3 Plakophilin-3 1 YLMAS(1)DPNLQVLGAAYIQHK;Y(0.229)LMAS(0.771)DPNLQVLGAAYIQHK 167.34 2.1044e-08 8784000.0 31109.0 30515.2 43141.0 58110.0 51045.0 49255.0 42304.0 48034.0 41344.0 45907.0 True False 41001.01489260261 40378.64164274009 42568.922152171355 44713.63729055036 43958.282850836484 46175.07706362293 46068.974046292904 40611.44901151197 43529.35943455112 44299.809903003304 0.9255347818055297 0.9114856639599851 0.9609278740784257 1.0093415161025103 0.9922905526476387 1.0423312687960877 1.0399361565470207 0.9167409318557531 0.9826082669397651 1.0 15.435012887526518 -5.492571556487763 3.2727966748049404 0.997414713284786 0.9190964163276614 0.47793031312641665 0.033021987300420885 0.22646266375624943 4.9184869905533555 0.009913969154003036 0.02148315457936966 3.2168324679423343e-06 5.492571556487763 -0.07831829695712467 YLMAS(ph)DPNLQVLGAAYIQHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 YLMASDPNLQVLGAAYIQHK 20 0 Q9Y446;Q9Y446-2;E9PKC4 Q9Y446 PKP3 Plakophilin-3 1 Y(0.023)LMAS(0.977)DPNLQVLGAAYIQHK;Y(0.139)LMAS(0.861)DPNLQVLGAAYIQHK;Y(0.036)LMAS(0.964)DPNLQVLGAAYIQHK 80.453 0.00099105 10079000.0 51459.9 45887.0 46095.9 64721.0 69291.0 54532.1 58974.3 59612.1 57453.0 43206.8 True False 60171.04469064596 50442.35810338182 47195.001075674256 61094.89219831306 55713.925959605425 51672.34067772443 53387.82736704253 58047.34553924092 58293.14143460262 51039.85081515939 1.1789032242385493 0.9882936038755014 0.9246696516921799 1.1970037377179639 1.0915769750458946 1.012392078982668 1.046002809851195 1.1372945769269418 1.1421103413039155 1.0 15.639336491792038 -5.758705029208999 24.99972470416733 1.090266991173366 1.0263893451835646 0.09656631520410341 0.08217324341123874 169.8180892720501 1552583.0719463937 0.023042108831514602 0.037736176091817716 1.7429903023582797e-06 5.758705029208999 -0.06387764598980139 YLMAS(ph)DPNLQVLGAAYIQHK ddPTM_PC-9_Lapatinib_30min_R1 4 YLMASDPNLQVLGAAYIQHK 20 0 Q9Y446;Q9Y446-2;E9PKC4 Q9Y446 PKP3 Plakophilin-3 1 YLMAS(1)DPNLQVLGAAYIQHK;Y(0.001)LMAS(0.999)DPNLQVLGAAYIQHK;Y(0.389)LMAS(0.611)DPNLQVLGAAYIQHK;Y(0.011)LMAS(0.989)DPNLQVLGAAYIQHK 135.54 4.759e-06 12348600.0 65293.1 53492.1 58797.1 51346.3 58429.2 54217.7 52839.1 52168.4 53684.6 39306.1 True False 64362.00842071195 53368.24232899485 53963.0294013695 55122.47818823556 54992.50933222705 51898.93535863172 55574.85005429808 54592.33431410744 47638.07502410005 46100.10701291392 1.3961357704155082 1.1576598361050425 1.1705619118466029 1.1957125863676243 1.192893311870667 1.1257877415359012 1.205525402332147 1.1842127459447027 1.0333614846220487 1.0 15.492482479158966 -1.5228787457721735 0.05324962907564012 0.6893501658047049 2.088613945818715 0.5933629343907388 0.06481755334943753 335.9522371554222 1.351234795672869 7.974423942012793 37.83240477417698 0.029999999966025176 1.5228787457721735 1.3992637800140102 YLNQDYEALR ddPTM_PC-9_Lapatinib_30min_R1 1 YLNQDYEALR 10 0 P17655 P17655 CAPN2 Calpain-2 catalytic subunit 0 157.34 0.0017228999999999999 10012000.0 36519.0 62982.0 52069.0 43154.0 47311.0 46037.0 45078.0 34750.0 44912.0 51263.0 False True 35998.232363235584 62836.169048602555 47788.08781215245 46327.68911752393 44528.259997004825 44068.104827488605 47411.91827165204 36364.61186111196 39853.537615673464 60123.741246346115 0.5987357342873818 1.0451140888113193 0.7948289115334563 0.7705390276314416 0.7406102659939002 0.7329567973311498 0.7885723224938765 0.604829491766232 0.6628585778183834 1.0 15.87564716441277 -5.761381501238654 3.1447653958125015 0.7381462586644487 0.8400885362605399 0.01758345442338838 0.14007609911228389 0.6188131466733435 12.625953415250386 0.038516339896202345 0.06687527737719948 1.7322816253449053e-06 5.761381501238654 0.1019422775960912 YLPHSAGR ddPTM_PC-9_AZD4547_30min_R2 4 YLPHSAGR 8 0 M0R0F0;M0R0R2;P46782 M0R0F0 RPS5 40S ribosomal protein S5;40S ribosomal protein S5, N-terminally processed 0 ;;; 135.77 0.0029116999999999997 39070300.0 126251.2 112271.0 143232.0 227375.0 163533.0 157707.0 126841.0 164454.0 132717.0 161619.0 False True 166396.45541190458 148560.4051709335 141332.65009387385 174957.2066587316 140829.26573505392 147845.55635920822 138129.60327642382 139041.41307697026 139732.14967287463 155960.76800299488 1.0669122596825715 0.95254984361247 0.9062064255233718 1.121802674473698 0.9029787910017832 0.9479663267391013 0.8856689092078037 0.8915153141224611 0.8959442266287851 1.0 17.250823638615493 YLPHSAGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 YLPHSAGR 8 0 M0R0F0;M0R0R2;P46782 M0R0F0 RPS5 40S ribosomal protein S5;40S ribosomal protein S5, N-terminally processed 0 ;;;; 159.2 2.785e-05 31432700.0 114231.8 116801.4 139051.2 139722.6 146222.3 143390.0 146383.2 150499.5 135239.4 107717.5 False True 133568.9875591078 128396.67107843893 142366.70796261253 131894.39570878126 117571.08998056316 135870.37597633168 132516.72357340844 146549.0475924012 137217.02037719142 127245.83005873892 1.0496924535558454 1.00904423366305 1.1188320112092753 1.0365321649274988 0.9239681168828108 1.0677786133629017 1.0414229174522762 1.151700197364044 1.0783616273621668 1.0 16.9572588533142 -7.554829142240003 24.991388304366424 1.0883309076160925 1.0339633360744966 0.08854274006839402 0.0576519571206689 380.97566716678534 297992.62554536405 0.027258787641091714 0.015738030273611987 2.7872174848223918e-08 7.554829142240003 -0.05436757154159588 YLPHSAGR ddPTM_PC-9_Lapatinib_30min_R1 4 YLPHSAGR 8 0 M0R0F0;M0R0R2;P46782 M0R0F0 RPS5 40S ribosomal protein S5;40S ribosomal protein S5, N-terminally processed 0 ;;; 152.47 0.00017624 37449700.0 154434.0 134784.0 151153.0 136710.0 132181.0 153601.0 124427.0 122935.0 144814.0 121532.0 False True 152231.742840273 134471.91592910394 138725.78380745323 146764.10945119112 124406.37345784479 147031.8432914193 130869.2212340131 128647.00889628202 128503.52236097568 142538.64426878918 1.0680033026917617 0.9434067274803485 0.9732503386650294 1.0296443480578772 0.8727904919822876 1.0315226726455822 0.9181315137755153 0.9025412691149824 0.9015346190514688 1.0 17.120993582041834 -1.5228787452803376 0.5217789233715661 0.9389157740686681 4.757842117283579 0.25511621113744243 0.05430667509814645 172.3666337864195 1.7211973932128244 0.02804962895158914 729.035523994028 0.029999999999999995 1.5228787452803376 3.8189263432149114 YLPT(ph)VVEYPNSAALR ddPTM_PC-9_Lapatinib_30min_R1 2 YLPTVVEYPNSAALR 15 0 Q5TIE3 Q5TIE3 VWA5B1 von Willebrand factor A domain-containing protein 5B1 1 Y(0.017)LPT(0.589)VVEY(0.393)PNSAALR;Y(0.003)LPT(0.498)VVEY(0.498)PNSAALR 111.5 0.0021473000000000004 0.0 35987.0 34372.0 40991.0 35105.0 38689.0 34007.0 38565.0 31811.0 36355.0 36182.0 True False 35473.81878079246 34292.413745809376 37620.878209835806 37686.73880684704 36413.38908550059 32552.599884188898 40561.70700000576 33289.05519176498 32260.31706487815 42436.010490515524 0.8359367049529994 0.8080970230100625 0.8865319283075419 0.8880839261567731 0.858077577618636 0.7670984974297813 0.9558322408528795 0.7844529871441404 0.7602108843876441 1.0 15.37300141101204 -10.994526859345338 3.021250804685939 1.004036339742667 0.8406217495190047 0.4083167201160085 0.05834799059212456 37617434.13208334 44180101.49578734 1273529.292240308 0.014663670273081023 1.0126821166123206e-11 10.994526859345338 -0.16341459022366234 YLQAHTQSVYNYHLS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 YLQAHTQSVYNYHLSPR 17 0 P50548;P50548-2 P50548 ERF ETS domain-containing transcription factor ERF 1 YLQAHTQSVYNYHLS(0.999)PR 84.70700000000001 0.0019038 11172000.0 10834.0 10007.0 20692.0 33759.0 35153.0 22481.0 15918.0 24610.0 18177.0 25839.0 True False 14278.986638800898 13241.567052449282 20417.61056008737 25976.384121350693 30272.612734948667 21075.259516136586 17334.67116274797 20807.089981540357 19137.79911091901 24934.384474779486 0.5726624875478173 0.531056504155649 0.8188536027724799 1.0417896679031786 1.2140910382435415 0.8452287858741285 0.6952115132531771 0.8344737766671647 0.7675264304308944 1.0 14.605848968911259 -5.355941374873227 3.968075656150666 0.9087555934095597 0.5503652198450079 0.5069829016812732 0.14030285395553396 0.20164734067946571 5.675463225016015 0.0423786152892411 0.0970283776815564 4.406143377322286e-06 5.355941374873227 -0.35839037356455183 YLQDQLS(ph)PLTR ddPTM_PC-9_AZD4547_30min_R2 1 YLQDQLSPLTR 11 0 H0YC17;E7EMV7;A0A0A0MRZ4;Q15025-7;Q15025-8;Q15025-5;Q15025-6;Q15025-4;Q15025-3;Q15025-2;Q15025 H0YC17 TNIP1 TNFAIP3-interacting protein 1 1 Y(0.001)LQDQLS(0.612)PLT(0.388)R 79.875 0.016794 3017200.0 11816.0 10982.0 15034.0 18697.0 16639.0 16179.0 16545.0 20658.0 13921.0 14711.0 True False 15573.242211932002 14531.716735285092 14834.639336958904 14386.695515770436 14328.962060046395 15167.324572375508 18017.472948088034 17465.780773614828 14656.835639715222 14195.972367679911 1.0970183520072025 1.0236506777351562 1.0449893077231576 1.01343501826791 1.0093681284326295 1.068424492492468 1.2691961129135871 1.2303335284999086 1.032464368068549 1.0 13.793194050872021 -7.017779564919163 24.06530266636649 1.1545668848555073 1.0362625895511703 0.22679769875709632 0.07927879878311285 539.5691219426718 730325.416285705 0.02929155357809927 0.02319830949209416 9.598877186090873e-08 7.017779564919163 -0.11830429530433695 YLQDQLS(ph)PLTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YLQDQLSPLTR 11 0 H0YC17;E7EMV7;A0A0A0MRZ4;Q15025-7;Q15025-8;Q15025-5;Q15025-6;Q15025-4;Q15025-3;Q15025-2;Q15025 H0YC17 TNIP1 TNFAIP3-interacting protein 1 1 YLQDQLS(0.939)PLT(0.061)R;YLQDQLS(0.688)PLT(0.312)R 101.43 0.0037364000000000004 8647300.0 48390.0 48095.0 46847.0 47593.0 59498.0 50633.0 54622.0 52040.0 40263.0 39280.0 True False 56581.47125393472 52869.553751218205 47964.01014823683 44926.51850858788 47839.7940099667 47977.71634569773 49447.80873096584 50674.005140937756 40851.77020488754 46401.1530596911 1.219397957226354 1.1394017231254159 1.0336814278415722 0.9682198727000116 1.031004422420816 1.0339768126877906 1.0656590509152968 1.092085040984865 0.8804042035838041 1.0 15.501873036040854 -5.087565300247739 2.348000825439005 1.0168704083835987 1.219918067038952 0.6120952089265117 0.054797001401215434 0.23677421640393675 2.285824176104859 0.014745260641078374 0.07452392091769412 8.174001249297645e-06 5.087565300247739 0.20304765865535335 YLQDQLS(ph)PLTR ddPTM_PC-9_Lapatinib_30min_R1 2 YLQDQLSPLTR 11 0 H0YC17;E7EMV7;A0A0A0MRZ4;Q15025-7;Q15025-8;Q15025-5;Q15025-6;Q15025-4;Q15025-3;Q15025-2;Q15025 H0YC17 TNIP1 TNFAIP3-interacting protein 1 1 YLQDQLS(0.999)PLT(0.001)R;YLQDQLS(0.99)PLT(0.01)R 106.58 0.0024166 8248600.0 47781.0 45414.0 54269.0 43468.0 60645.0 48249.0 43219.0 42506.0 53324.0 31721.0 True False 47099.634178037755 45308.84667322782 49807.212304398 46664.78172499719 57077.98033265745 46185.502743912424 45456.66834780891 44480.98393578207 47318.08959338642 37203.93258442434 1.265985365153476 1.2178510046058046 1.338762029830419 1.2542970187117717 1.5341921234572256 1.241414537001077 1.221824285501464 1.1955989823077011 1.271857201816252 1.0 15.183167506801599 -9.161219024887565 0.5641380196994661 0.9885848521875344 1.3064854940448933 0.4851962100041829 0.0897824116949659 2.056363126906393 1.0365664604365696 0.1550524860515834 0.041998898087689425 6.898917874909616e-10 9.161219024887565 0.3179006418573589 YLQDQLSPLT(ph)R ddPTM_PC-9_AZD4547_30min_R2 1 YLQDQLSPLTR 11 0 H0YC17;E7EMV7;A0A0A0MRZ4;Q15025-7;Q15025-8;Q15025-5;Q15025-6;Q15025-4;Q15025-3;Q15025-2;Q15025 H0YC17 TNIP1 TNFAIP3-interacting protein 1 1 YLQDQLS(0.479)PLT(0.521)R 98.368 0.012237999999999999 6951700.0 17790.0 21826.0 25518.0 36865.0 32946.0 26770.0 23359.0 30095.0 19253.0 25037.0 True False 23446.84994501271 28880.827669307288 25179.614646835005 28366.34380857235 28372.016589355655 25096.0676681187 25437.905747620905 25444.50926430137 20270.674274221485 24160.462250669698 0.9704636319349723 1.1953756252534757 1.042182653030037 1.1740811708925838 1.174315966929367 1.0387246488805515 1.0528733053075505 1.0531466244440784 0.8390019223932526 1.0 14.560360436876728 -8.081421174546566 4.527601522637294 0.9206327768154666 1.0965274559228964 0.4379970568001127 0.07695557356773154 0.1965144366443848 7.099381111359124 0.053497263698390446 0.019318998496546096 8.29046376454018e-09 8.081421174546566 0.17589467910742973 YLS(ph)FTPPEK ddPTM_PC-9_AZD4547_30min_R2 2 YLSFTPPEK 9 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 YLS(0.5)FT(0.5)PPEK;YLS(0.94)FT(0.06)PPEK 141.1 0.0007373999999999999 67733200.0 65718.0 106811.0 87647.0 106436.0 98492.0 107108.0 91913.0 103767.0 97750.0 99608.0 True False 86614.95698068276 141335.5669470531 86484.74351246758 81898.82461980748 84818.08589567203 100410.51982804836 100093.07894092542 87732.1944784436 102916.8654394199 96120.75423831579 0.9011056734525309 1.470395941719668 0.8997509871597836 0.8520410110053096 0.8824117805544823 1.0446289214408035 1.0413263996322886 0.9127289436465084 1.0707038896537813 1.0 16.552560348570793 -5.350380774459715 24.999783889429143 0.9587108028871456 1.1859173946241488 0.2709758432486499 0.1460452502732114 72.13347036686822 20272.77787790128 0.03609123335401284 0.07512991645561454 4.462921269823061e-06 5.350380774459715 0.2272065917370032 YLS(ph)FTPPEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 YLSFTPPEK 9 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 Y(0.003)LS(0.961)FT(0.036)PPEK;Y(0.01)LS(0.944)FT(0.045)PPEK;YLS(0.995)FT(0.005)PPEK;Y(0.006)LS(0.99)FT(0.005)PPEK;Y(0.004)LS(0.966)FT(0.03)PPEK;Y(0.045)LS(0.773)FT(0.182)PPEK 135.86 0.0010345999999999999 712162000.0 642192.0 975042.0 821549.0 796248.0 888488.0 594644.0 846767.0 594753.0 600577.0 610523.0 True False 750902.421729838 1071837.7259319131 841137.8439019333 751636.8060308472 714395.1544644751 563459.8218290651 766555.0996978101 579141.3639428933 609359.302444944 721205.9870025899 1.0411760790432005 1.4861741932933568 1.1662934848860493 1.0421943516508108 0.9905563283432778 0.7812744652479454 1.0628795566211202 0.8030179648811119 0.8449171435438401 1.0 19.4600518476118 -5.915162628952307 1.7707171728653601 0.901309776041769 1.2723064269129363 0.5440144893081937 0.13119269715897938 0.24332527174036545 1.550627960116609 0.040802568037633685 0.07264870643768122 1.2157306643812422e-06 5.915162628952307 0.3709966508711673 YLS(ph)FTPPEK ddPTM_PC-9_Lapatinib_30min_R1 2 YLSFTPPEK 9 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 YLS(0.678)FT(0.322)PPEK;Y(0.004)LS(0.96)FT(0.036)PPEK 144.17 0.00056359 320953000.0 174641.0 265773.0 252053.0 218454.0 301314.0 310169.0 299870.0 304293.0 279225.0 218861.0 True False 172150.5873147626 265157.618947545 231330.1752927164 234519.83590118116 283591.3029261163 296903.7949092533 315395.80132482154 318431.5636562112 247775.74013039767 256690.8322360486 0.6706534308808342 1.032984375163467 0.9012015477046295 0.9136276268936657 1.1047971618453847 1.1566591308419834 1.2286991264058424 1.240525658366275 0.9652691448775516 1.0 17.969672245130916 -6.269160304239252 3.051523347410295 1.140220363737641 0.8861637728845774 0.49194039738420603 0.11691979697590862 0.21797997961325133 4.147461222466135 0.036786618067111 0.04562376776135336 5.380711361859999e-07 6.269160304239252 -0.25405659085306354 YLS(ph)FTPPEKDGFPSGTPALNAK ddPTM_PC-9_AZD4547_30min_R2 2 YLSFTPPEKDGFPSGTPALNAK 22 1 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 Y(0.171)LS(0.794)FT(0.035)PPEKDGFPSGTPALNAK;Y(0.032)LS(0.461)FT(0.15)PPEKDGFPS(0.273)GT(0.083)PALNAK 71.696 0.00071701 1303123900.0 163544.0 178740.0 245265.0 334147.0 266540.0 248450.0 194626.0 249595.0 208715.0 264850.0 True False 215547.59007347716 236514.2095487944 242012.62584669603 257114.57166968708 229535.52181529923 232914.38222428405 211947.33695947911 211025.82787251408 219747.24879988228 255577.6821140658 0.8433740704216772 0.9254102611480636 0.9469239404819565 1.00601339499955 0.8981047167993964 0.9113251998284146 0.8292873431134953 0.8256817501707056 0.8598060948913677 1.0 17.963402335333875 -6.9523598803799915 2.744085416094675 0.8647910956106365 0.930386611959168 0.08556726881974985 0.059987929314471854 0.4605875178929246 7.042376893499616 0.023746221287054763 0.01968412795187127 1.115938136596609e-07 6.9523598803799915 0.06559551634853156 YLS(ph)FTPPEKDGFPSGTPALNAK ddPTM_PC-9_Lapatinib_30min_R1 4 YLSFTPPEKDGFPSGTPALNAK 22 1 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 Y(0.004)LS(0.916)FT(0.08)PPEKDGFPSGTPALNAK;Y(0.063)LS(0.46)FT(0.46)PPEKDGFPS(0.014)GT(0.003)PALNAK;Y(0.085)LS(0.539)FT(0.374)PPEKDGFPS(0.002)GTPALNAK;Y(0.01)LS(0.939)FT(0.051)PPEKDGFPSGTPALNAK 78.098 0.00029912 794786600.0 150176.0 149758.1 127652.6 128544.1 118243.4 126581.0 105786.9 100652.4 136395.7 91739.2 True False 148034.46270109486 149411.34432056049 117157.49598128584 137997.66192454688 111288.55568746894 121167.42570472285 111264.02806272288 105329.07795365124 121033.37995560444 107596.19848520005 1.375833577628276 1.388630327316928 1.088862781684624 1.2825514643394076 1.0343167997963867 1.1261311032414358 1.0340888398397026 0.9789293621571523 1.1248852808889218 1.0 16.715267580923964 -4.47192077097961 0.4433984811907357 1.0213279555447847 1.8103240278830137 0.7071413969837083 0.07816102674785771 3.42255874149336 0.42681173243634746 0.052754183248512825 1.504726350122815 3.373488461222055e-05 4.47192077097961 0.788996072338229 YLSDSCS(ph)PR ddPTM_PC-9_AZD4547_30min_R2 1 YLSDSCSPR 9 0 P83436 P83436 COG7 Conserved oligomeric Golgi complex subunit 7 1 YLSDS(0.002)CS(0.998)PR 88.134 0.010353 11715000.0 42738.0 37394.0 52635.0 68630.0 59695.0 50594.0 49224.0 58500.0 44056.0 48403.0 True False 56327.79499437625 49480.87922047452 51937.025508901956 52808.41382293008 51407.37966070495 47430.34918194983 53604.84064047657 49460.16919626619 46384.71021789343 46708.4257027266 1.205945054814556 1.0593566037826463 1.1119412552984018 1.13059716803616 1.1006018483235682 1.0154559582850828 1.147648199098849 1.0589132143106883 0.9930694413274932 1.0 15.511395199786154 -1.522888612623803 0.08802639121233012 0.9223477012829796 1.5492585237003595 0.4682273116658163 0.04803029218868876 158.6096187892266 1.0106375964599434 0.9689096083749004 12.015834606138561 0.029999318395804057 1.522888612623803 0.6269108224173799 YLSDSCS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 2 YLSDSCSPR 9 0 P83436 P83436 COG7 Conserved oligomeric Golgi complex subunit 7 1 YLSDS(0.002)CS(0.998)PR;YLSDS(0.003)CS(0.997)PR 98.75399999999999 0.0043606 14675500.0 71787.0 101060.0 108197.0 102202.0 95562.0 101980.0 101940.0 92290.0 105517.0 77116.0 True False 70763.30421587634 100826.00177910768 99301.46031249824 109718.2760158778 89941.23104212072 97618.55312699094 107217.95440374926 96578.13032120917 93632.56431673089 90445.39784938893 0.7823870080566453 1.1147720522718547 1.0979161203741572 1.2130885443014177 0.9944257328813153 1.07930923461188 1.1854440021623902 1.067805909616679 1.035238569823633 1.0 16.464759475333715 -4.759097157312882 24.997064656420868 1.0938122033177669 0.7823866027844585 0.6443105005298271 0.06787881543347944 38.289779873981104 408551.903155873 0.016580538035001844 0.10818895202255392 1.741417252168116e-05 4.759097157312882 -0.31142560053330837 YLSEVASGDNK ddPTM_PC-9_Lapatinib_30min_R1 2 YLSEVASGDNK 11 0 P31946-2;P31946 P31946-2 YWHAB 14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed 0 ; 167.93 0.00099246 19492600.0 90712.0 88350.0 95060.0 90583.0 93522.0 93235.0 78866.0 73859.0 93762.0 91353.0 False True 89418.43024545664 88145.43100320802 87244.5337422115 97244.7759960299 88021.21983132628 89247.55639140045 82949.29558569826 77290.75877553572 83201.53620236857 107143.2443297792 0.834568999705041 0.8226877163799775 0.8142793723296179 0.9076146294088078 0.8215284162984956 0.8329741828304441 0.7741906277393121 0.7213778083631697 0.7765448649872896 1.0 16.709181361509728 -7.124915977969312 5.404523938023295 0.7950022064268475 0.8401849165128402 0.0 0.07357648989195029 0.6445875749170817 25.729009206363546 0.027229537682473586 0.021022627884832567 7.500393038069758e-08 7.124915977969312 0.04518271008599273 YLSFT(ph)PPEK ddPTM_PC-9_AZD4547_30min_R2 1 YLSFTPPEK 9 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 Y(0.018)LS(0.299)FT(0.683)PPEK 125.48 0.0034847999999999997 300680000.0 223460.0 272310.0 366810.0 303670.0 238210.0 332620.0 365000.0 350240.0 305980.0 307550.0 True False 294515.63174325734 360328.8821877153 361945.8597306036 233663.57315473104 205138.65330390353 311821.2188184401 397484.29290130764 296118.45571453474 322153.47812944936 296782.7681109341 0.9923609568638118 1.2141165893197288 1.2195649431887239 0.7873219009379621 0.6912081001523139 1.050671576396527 1.3393105517256056 0.9977616207280907 1.0854857921165826 1.0 18.1790478026401 -5.7066833168048445 24.999986585054607 0.9972561356680598 1.1492244465375319 0.13399337492766716 0.17295951795416403 209.0488705070284 95443.31432050069 0.05225604145018981 0.09051005130018176 1.964792461628844e-06 5.7066833168048445 0.15196831086947205 YLSFT(ph)PPEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YLSFTPPEK 9 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 YLS(0.426)FT(0.574)PPEK 85.958 0.029423 3350900.0 42280.0 90445.0 59411.0 50965.0 53362.0 38090.0 52550.0 39901.0 31460.0 26626.0 True False 49437.16893193556 99423.78186981843 60827.58355747217 48109.596280759346 42906.09916232218 36092.493346387266 47572.08357094675 38853.64102860412 31920.042983527368 31453.083028699988 1.5717749794773896 3.1610186441531734 1.9339148248827893 1.5295669501416058 1.3641301592969968 1.1475025616234171 1.5124776012430534 1.235288794842507 1.0148462379475263 1.0 14.940913816438412 -5.728226734814927 2.481204116445332 1.2505740915466161 2.3944646329010024 0.5755667895414893 0.39248784787030283 0.18189505254593658 2.2785009016988798 0.10858323430366344 0.204793976322854 1.869705756628892e-06 5.728226734814927 1.1438905413543863 YLSFT(ph)PPEK ddPTM_PC-9_Lapatinib_30min_R1 1 YLSFTPPEK 9 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 YLS(0.259)FT(0.741)PPEK 107.79 0.0060615 244160000.0 103980.0 156810.0 163000.0 145680.0 192830.0 167170.0 203280.0 171360.0 179530.0 130330.0 True False 102497.22613240358 156446.91607937732 149598.7691981954 156393.79317423343 181488.11851836657 160020.5287923032 213804.8437433211 179322.0111804362 159309.44086528875 152857.36684619103 0.67054161828876 1.0234829979558537 0.9786821026998684 1.0231354654408042 1.1873037084367974 1.0468617384553007 1.398721227210835 1.1731329335332237 1.0422097681794424 1.0 17.221826557943054 -4.191506276161661 0.7059713110217734 1.1543609502670418 1.1141684553510223e-11 0.5580999262948819 0.1167581539839021 4.642115214197724 0.9672924631463145 0.04778539654376888 5.175972968689308 6.434187666255373e-05 4.191506276161661 -1.1543609502559 YLSFT(ph)PPEKDGFPSGTPALNAK ddPTM_PC-9_AZD4547_30min_R2 2 YLSFTPPEKDGFPSGTPALNAK 22 1 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 Y(0.003)LS(0.077)FT(0.893)PPEKDGFPS(0.014)GT(0.014)PALNAK;YLS(0.045)FT(0.953)PPEKDGFPS(0.001)GT(0.001)PALNAK 81.643 0.00029456 783191300.0 89499.0 92358.0 109370.0 177504.0 131645.0 119563.0 110395.0 106487.0 102024.0 123698.0 True False 117957.82030515415 122210.91734087249 107919.68233891153 136583.19520946237 113368.36410810798 112086.70670912472 120219.94113654736 90031.88097782544 107416.78035387596 119367.37067074113 0.988191493557523 1.0238218087083018 0.9040970051739976 1.144225548757447 0.9497433299491819 0.9390062466760773 1.0071424080216858 0.7542419714191937 0.8998839444170278 1.0 16.865049001116276 -7.720031296257105 24.999939279432212 0.8702968127189405 0.9934453725762756 0.26391780972437673 0.08239921303908031 160.8624268105294 97119.83416130304 0.037183664270330354 0.021467742738550188 1.9053234110381195e-08 7.720031296257105 0.12314855985733508 YLSFT(ph)PPEKDGFPSGTPALNAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YLSFTPPEKDGFPSGTPALNAK 22 1 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 Y(0.014)LS(0.071)FT(0.845)PPEKDGFPS(0.031)GT(0.039)PALNAK;Y(0.011)LS(0.327)FT(0.61)PPEKDGFPS(0.021)GT(0.03)PALNAK 69.081 0.0015306 1176630000.0 220179.0 206120.0 206417.0 292230.0 285590.0 295730.0 292140.0 275690.0 289240.0 221820.0 True False 257450.95596652353 226582.23140037645 211338.76412083188 275857.3005224426 229630.68962496845 280221.3981970887 264466.38428956043 268453.42961769993 293469.58781167964 262034.21007384648 0.9825089475682153 0.8647047701768447 0.8065311932410367 1.0527529991015314 0.8763385878517692 1.0694076858060506 1.0092818957304412 1.0244976392282688 1.1199666933908135 1.0 17.99939565063456 -6.587557884663876 1.0500772333441535 1.0506545223845398 0.897139113208215 0.3879377566370411 0.07432173515561181 0.5060815763886781 1.1970223086935 0.03699189191963936 0.040046021791100256 2.584890291142381e-07 6.587557884663876 -0.15351540917632478 YLSFT(ph)PPEKDGFPSGTPALNAK ddPTM_PC-9_Lapatinib_30min_R1 2 YLSFTPPEKDGFPSGTPALNAK 22 1 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 YLS(0.108)FT(0.451)PPEKDGFPS(0.22)GT(0.22)PALNAK;Y(0.001)LS(0.016)FT(0.969)PPEKDGFPS(0.006)GT(0.008)PALNAK 91.62200000000001 0.00014233 619240000.0 184253.0 166732.0 144445.0 138279.0 141311.0 132050.0 112058.0 108364.0 146974.0 98743.0 True False 181625.51843213782 166345.9422979839 132569.28967382456 148448.49894522125 132999.36480811538 126402.52932358462 117859.81493599513 113398.98704223127 130420.2404151671 115810.59598322309 1.5682979341410954 1.436362026166255 1.1447077752110801 1.2818213884913108 1.1484213830259742 1.091459103982989 1.0176945722053699 0.9791762668992638 1.126151189430546 1.0 16.821407731849483 -1.522878747079122 0.35611280658095873 1.0085434372492184 8.185871684568767 0.8779005401305745 0.06432842681176265 19.750477686409923 0.27664754902790495 0.05360675834771208 95.73679651702646 0.02999999987574437 1.522878747079122 7.177328247319548 YLSFTPPEKDGFPSGT(ph)PALNAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YLSFTPPEKDGFPSGTPALNAK 22 1 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 Y(0.02)LS(0.005)FT(0.02)PPEKDGFPS(0.418)GT(0.538)PALNAK 51.486999999999995 0.01881 5929900.0 45540.0 32916.0 43737.0 61347.0 61207.0 62906.0 64181.0 62698.0 60509.0 47031.0 True False 53249.02254400056 36183.68294573446 44779.85595349616 57909.92647965746 49213.92772812586 59607.09862031603 58101.31104979895 61052.24393402221 61393.82965321859 55557.34800280882 0.9584514822649282 0.6512852799220206 0.8060114019703067 1.0423450463605588 0.8858221188966353 1.0728931592865532 1.0457898574795454 1.0989049356879954 1.10505328026303 1.0 15.761690114316718 -6.0772916383059945 1.0599918991515547 1.068267272390138 0.7842414327217512 0.5329559205651031 0.09491711840578763 0.3877442229108876 0.895201288344553 0.03894304157441952 0.07338292513618694 8.369670515711751e-07 6.0772916383059945 -0.2840258396683869 YLSPGWGS(ph)ASEEEPSR ddPTM_PC-9_AZD4547_30min_R2 2 YLSPGWGSASEEEPSR 16 0 Q9BRS8;H0YMC6;Q9BRS8-2 Q9BRS8 LARP6 La-related protein 6 1 YLSPGWGS(0.683)AS(0.316)EEEPS(0.001)R;YLS(0.001)PGWGS(0.995)AS(0.004)EEEPSR 154.31 3.0193e-05 11731400.0 23179.0 25361.0 33215.0 43275.0 33499.0 33810.0 35354.0 31587.0 30687.0 31895.0 True False 30549.43984684934 33558.447288614596 32774.54739770453 33298.61734208512 28848.24208483048 31695.855355214524 38500.43751022688 26705.954947050584 32309.05217124786 30778.365758082422 0.9925621160969871 1.0903258331642292 1.0648566481830801 1.0818838662134256 0.9372895985309067 1.0298095618313057 1.2508928450860533 0.8676859309866892 1.0497325434753948 1.0 14.90962901032854 YLSPGWGS(ph)ASEEEPSR ddPTM_PC-9_Lapatinib_30min_R1 2 YLSPGWGSASEEEPSR 16 0 Q9BRS8;H0YMC6;Q9BRS8-2 Q9BRS8 LARP6 La-related protein 6 1 YLS(0.001)PGWGS(0.985)AS(0.015)EEEPSR;YLSPGWGS(0.921)AS(0.078)EEEPS(0.001)R 148.33 3.5363e-10 5539700.0 28419.0 30589.0 37512.0 25528.0 26444.0 30300.0 29138.0 27175.0 28190.0 23597.0 True False 28013.739848593676 30518.173049882545 34427.90816050743 27405.41427891158 24888.61591090433 29004.13963274982 30646.62306667103 28437.64970721491 25014.94534613989 27675.710008973907 1.0122139536622605 1.102706056682447 1.2439756071061632 0.9902334671820638 0.8992945764655773 1.0479998389687262 1.1073473112969385 1.0275309900990415 0.903859208599481 1.0 14.756332708779807 -5.843889363212229 24.999999955559677 1.0004560252861803 1.1179683629573582 0.340344144529384 0.07834766556589226 32.985047664175845 9998.155725896639 0.023297745806400205 0.03455615372604351 1.4325527965032692e-06 5.843889363212229 0.11751233767117797 YLSVPPSPNIS(ph)TSESRSPPEGDTTLFLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YLSVPPSPNISTSESRSPPEGDTTLFLSR 29 1 Q9BTC0;Q9BTC0-1 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 YLSVPPS(0.024)PNIS(0.275)T(0.275)S(0.275)ES(0.067)RS(0.067)PPEGDT(0.008)T(0.008)LFLS(0.003)R 42.708 0.022695 4867100.0 13617.0 7531.2 11578.0 17527.0 17016.0 16862.0 14655.0 17065.0 17345.0 14428.0 True False 15922.08915199069 8278.847764033146 11854.06342980952 16545.019013300687 13681.836950378058 15977.727036145503 13266.772306988107 16617.061831862087 17598.637811483866 17043.682188014845 0.9341930327231247 0.4857429088800335 0.6955107059051666 0.9707420515582708 0.8027512364669153 0.9374574613566237 0.7783982452053307 0.9749690030917874 1.03256078219173 1.0 14.056949434626368 -6.531863476339374 0.4529494877001133 1.0102506949334515 0.6668232475501925 0.33774540724316204 0.13207726607706577 1.5104584988138499 0.6221144266825985 0.12450852546797593 0.22680212305112063 2.9385732688742837e-07 6.531863476339374 -0.34342744738325903 YLSVPPSPNIS(ph)TSESRSPPEGDTTLFLSR ddPTM_PC-9_Lapatinib_30min_R1 1 YLSVPPSPNISTSESRSPPEGDTTLFLSR 29 1 Q9BTC0;Q9BTC0-1 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 YLS(0.001)VPPS(0.078)PNIS(0.331)T(0.331)S(0.084)ES(0.031)RS(0.098)PPEGDT(0.005)T(0.005)LFLS(0.034)R 40.819 0.033145 2077600.0 5607.3 3814.8 4674.2 3398.3 3980.8 3222.0 3092.4 3367.8 5176.3 4281.8 True False 5527.338873747121 3805.9670649806158 4289.905318933778 3648.2223183964766 3746.6571705539227 3084.2025708488427 3252.509340770591 3524.2802827583587 4593.290585144517 5021.903424860135 1.100646190523081 0.7578734083454852 0.8542389122214664 0.7264620622404907 0.7460631664095115 0.6141501159860996 0.6476646533403172 0.7017817716907835 0.9146513177466061 1.0 12.294018569381606 -2.488106717198337 1.3529902925206492 0.7476306879060408 199.8168071886535 0.3950347995725194 0.11629428393756285 757.7167233949859 3.265186948336939 0.03287130179282354 466185.80423258396 0.003250074249832205 2.488106717198337 199.06917650074746 YLSVPPSPNISTSES(ph)RSPPEGDTTLFLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YLSVPPSPNISTSESRSPPEGDTTLFLSR 29 1 Q9BTC0;Q9BTC0-1 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 YLSVPPS(0.042)PNIS(0.113)T(0.113)S(0.113)ES(0.261)RS(0.261)PPEGDT(0.045)T(0.022)LFLS(0.029)R 40.15 0.036851 4936800.0 4874.5 5010.3 4616.4 8430.7 11336.0 9810.4 4733.0 9531.0 8562.7 5036.9 True False 5699.656574236514 5507.689472080851 4726.472483794496 7958.355211698183 9114.792176156887 9295.925353777824 4284.655976047402 9280.821348929243 8687.913288463118 5950.050097921541 0.9579174091706397 0.925654302306595 0.7943584349727639 1.3375274293031882 1.5318849465386597 1.5623272410807192 0.7201041849284779 1.5597887742443042 1.4601411997351017 1.0 12.53868610026228 -5.76909188909447 24.717305951536865 1.3287261744040626 0.895944460969685 0.355315581154256 0.2569250851230809 156.8330010569817 506566.0086734037 0.07283449337380604 0.1104157429726762 1.7017983996096026e-06 5.76909188909447 -0.43278171343437755 YLSVPPSPNISTSES(ph)RSPPEGDTTLFLSR ddPTM_PC-9_Lapatinib_30min_R1 1 YLSVPPSPNISTSESRSPPEGDTTLFLSR 29 1 Q9BTC0;Q9BTC0-1 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 YLSVPPS(0.019)PNIS(0.117)T(0.117)S(0.117)ES(0.326)RS(0.177)PPEGDT(0.033)T(0.033)LFLS(0.06)R 41.205 0.031009 4353900.0 9018.6 6662.3 12440.0 9363.5 6752.5 9368.0 6696.8 6625.9 10656.0 5181.9 True False 8889.993110191312 6646.87385368049 11417.231219788673 10052.12302572033 6355.331225925783 8967.352477874605 7043.527536305943 6933.763503037175 9455.809067345386 6077.584510552271 1.462751047682836 1.0936703294112626 1.8785804129856825 1.6539668034672694 1.0457001815262743 1.4754796847834766 1.1589353507263522 1.1408748806369295 1.5558498694551488 1.0 12.569282334143072 -6.253272275490304 24.986554973919496 1.2452904889150258 1.5170826057160318 0.25400387834740856 0.24483578489396224 988.9736690163625 3025678.586639196 0.07349828771324132 0.09320899634065126 5.581201785679972e-07 6.253272275490304 0.271792116801006 YLSVPPSPNISTSESRS(ph)PPEGDTTLFLSR ddPTM_PC-9_AZD4547_30min_R2 2 YLSVPPSPNISTSESRSPPEGDTTLFLSR 29 1 Q9BTC0;Q9BTC0-1 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 YLSVPPS(0.001)PNIS(0.002)T(0.002)S(0.003)ES(0.063)RS(0.919)PPEGDT(0.004)T(0.004)LFLS(0.001)R;YLSVPPS(0.066)PNIS(0.058)T(0.058)S(0.058)ES(0.15)RS(0.521)PPEGDT(0.045)T(0.045)LFLS(0.001)R 83.73299999999999 8.9487e-08 15945200.0 19674.0 14072.1 32692.0 36054.0 30852.0 24902.8 24353.0 34256.0 22373.4 27540.0 True False 25929.922755378328 18620.631130086094 32258.48271942667 27742.307328747233 26568.732344284595 23345.62397929123 26520.369821987766 28962.52232456914 23556.012247798626 26575.83298252361 0.9756955792290674 0.7006603007450832 1.213827718613373 1.0438922966964272 0.9997328159669093 0.8784531417940284 0.997913022685975 1.0898067557699895 0.8863696676333407 1.0 14.697827291284092 -5.247987990087547 24.99983360301972 1.0121351603642998 0.8381779710107888 0.2916546822200532 0.10942335812935013 988.0143491392304 1836248.6072801328 0.02734135147053157 0.07144041267817242 5.649525977080701e-06 5.247987990087547 -0.173957189353511 YLSVPPSPNISTSESRS(ph)PPEGDTTLFLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YLSVPPSPNISTSESRSPPEGDTTLFLSR 29 1 Q9BTC0;Q9BTC0-1 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 YLSVPPS(0.026)PNIS(0.047)T(0.047)S(0.047)ES(0.117)RS(0.616)PPEGDT(0.06)T(0.026)LFLS(0.015)R 51.16 0.0051959 5109800.0 10617.0 8691.6 11287.0 12507.0 13403.0 11223.0 10481.0 14449.0 13467.0 10869.0 True False 12414.248404691578 9554.444607216717 11556.124886185864 11806.27333824109 10776.778364240541 10634.446123037655 9488.163804131173 14069.729059980971 13663.92939793906 12839.463661043344 0.9668821636497227 0.7441467073275174 0.9000473221672567 0.9195301026524112 0.8393480170779043 0.828262488510637 0.738984435379457 1.0958190646756076 1.0642134094274713 1.0 13.648297318013242 -7.7739028760880196 24.998075930813094 1.0600122531890015 0.8478053178225187 0.6384040871237158 0.07070701058693618 140.27351783549372 281342.7776844631 0.03757183361790017 0.018247593611578728 1.683050409768776e-08 7.7739028760880196 -0.21220693536648283 YLSVPPSPNISTSESRS(ph)PPEGDTTLFLSR ddPTM_PC-9_Lapatinib_30min_R1 1 YLSVPPSPNISTSESRSPPEGDTTLFLSR 29 1 Q9BTC0;Q9BTC0-1 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 YLSVPPS(0.024)PNIS(0.075)T(0.075)S(0.075)ES(0.174)RS(0.537)PPEGDT(0.019)T(0.019)LFLS(0.002)R 48.532 0.008614799999999999 5302000.0 14486.0 9225.0 16435.0 11258.0 10052.0 14559.0 10054.0 9058.3 11777.0 7265.8 True False 14279.426983592948 9203.640079282313 15083.777740934633 12085.950875587067 9460.761122992371 13936.345508686623 10574.546925400182 9479.18168694995 10450.55024269207 8521.683848930064 1.6756579141792258 1.0800259951485847 1.770046625565494 1.41825853784807 1.1101985582556213 1.6353980921782723 1.2408987604870914 1.1123601690691804 1.2263480349607412 1.0 13.056922813760782 -7.8629089569581305 0.59036115018002 1.0058085210925862 1.463980118899629 0.3210244469776483 0.21798376931175997 0.949433177487247 0.717701197689343 0.20721378273127572 0.11410516342771118 1.3711691801991164e-08 7.8629089569581305 0.45817159780704286 YLTAEAFGFK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YLTAEAFGFK 10 0 Q16658 Q16658 FSCN1 Fascin 0 149.72 0.00072571 2198400.0 15794.0 15266.0 18259.0 16880.0 22670.0 18373.0 20385.0 20159.0 15601.0 16257.0 False True 18467.612254280746 16781.507590520785 18694.363807643098 15934.268325698378 18227.97623795666 17409.487536182016 18453.98522538059 19629.84761022607 15829.135110807709 19204.265409658816 0.9616411698305539 0.8738427236107922 0.9734485234848264 0.8297254795116616 0.949162899445707 0.9065427479160899 0.9609315863807595 1.0221608164378526 0.824251007427049 1.0 14.229139159345984 -7.261672548579225 24.999989589293524 0.9536825879615687 0.9140577386282175 0.07283141669645099 0.06280853907257555 55.871339098995065 5989878.134280039 0.023694275051334025 0.017096068908535305 5.4742856012002e-08 7.261672548579225 -0.0396248493333512 YLTAEAFGFK ddPTM_PC-9_Lapatinib_30min_R1 2 YLTAEAFGFK 10 0 Q16658 Q16658 FSCN1 Fascin 0 ; 113.66 0.005875899999999999 7367100.0 47376.0 37521.0 53843.0 44969.0 42093.0 48707.0 36357.0 34637.0 39535.0 44745.0 False True 46700.40955230563 37434.12242978336 49416.2363799905 48276.17027218645 39617.17249802209 46623.91515156258 38239.387563832766 36246.361468585186 35082.15197799361 52479.11363103521 0.8898856387065167 0.7133146853998215 0.9416362617596998 0.9199120741939663 0.75491314080795 0.8884280226103138 0.7286591734891398 0.6906816628692016 0.6684974183185642 1.0 15.679455732681724 -7.269643937843644 24.34854729748939 0.7461830283623884 0.8479111656357741 0.09508793459564735 0.10861972312383707 794.4728407486856 2357732.0201919135 0.04321428341937179 0.029709681018930137 5.3747226963121444e-08 7.269643937843644 0.1017281372733857 YLVLDEADR ddPTM_PC-9_AZD4547_30min_R2 2 YLVLDEADR 9 0 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDT5;A0A2R8YDH3;A0A2R8Y7T2;O15523-2;O15523;D6RCM4;Q9NQI0-2;Q9NQI0-4;Q9NQI0;Q9NQI0-3 A0A2R8Y5G6 DDX3X;DDX3Y;DDX4 ATP-dependent RNA helicase DDX3X;ATP-dependent RNA helicase DDX3Y;Probable ATP-dependent RNA helicase DDX4 0 ; 120.07 0.0078282 4149500.0 25253.0 21463.0 33998.0 48581.0 37242.0 37064.0 27558.0 38612.0 28621.0 32546.0 False True 33282.92870496944 28400.495018159192 33547.164306101426 37381.40101896795 32071.59114371345 34746.38222081253 30010.608613080072 32645.40261549112 30133.847629070442 31406.574446231432 1.0597439960206534 0.9042850269067485 1.0681573809819571 1.190241268845334 1.0211744422691031 1.1063410395265776 0.9555517958336629 1.0394448675509194 0.9594757836662537 1.0 14.93877897459469 -7.269110593104153 24.93948327576512 0.9919051861919698 1.056076708548648 0.1892459913083684 0.070458280247211 1186.0533670052553 3855894.4759929804 0.03074550973078609 0.021173976586145147 5.38132729549414e-08 7.269110593104153 0.06417152235667822 YLVLDEADR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YLVLDEADR 9 0 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDT5;A0A2R8YDH3;A0A2R8Y7T2;O15523-2;O15523;D6RCM4;Q9NQI0-2;Q9NQI0-4;Q9NQI0;Q9NQI0-3 A0A2R8Y5G6 DDX3X;DDX3Y;DDX4 ATP-dependent RNA helicase DDX3X;ATP-dependent RNA helicase DDX3Y;Probable ATP-dependent RNA helicase DDX4 0 ; 109.71 0.010829 2974500.0 20855.2 26758.0 27593.0 28997.0 33280.0 31881.0 28374.0 24604.0 30130.0 21197.6 False True 24385.573451024167 29414.357402538648 28250.92176703523 27372.392099542423 26759.022902478944 30209.104236707044 25686.209310029364 23958.17107009286 30570.594249640173 25040.557079890732 0.9738430887628869 1.1746686508887765 1.128206600072913 1.093122329994979 1.0686272999879967 1.206407035607327 1.0257842598341047 0.9567746833129722 1.2208432165508984 1.0 14.611979037964378 YLVLDEADR ddPTM_PC-9_Lapatinib_30min_R1 4 YLVLDEADR 9 0 A0A2R8Y5G6;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8YFR4;A0A0D9SF53;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;F6S8Q4;A0A2R8YF78;A0A0D9SFB3;A0A0D9SG12;A0A2R8YDT5;A0A2R8YDH3;A0A2R8Y7T2;O15523-2;O15523;D6RCM4;Q9NQI0-2;Q9NQI0-4;Q9NQI0;Q9NQI0-3 A0A2R8Y5G6 DDX3X;DDX3Y;DDX4 ATP-dependent RNA helicase DDX3X;ATP-dependent RNA helicase DDX3Y;Probable ATP-dependent RNA helicase DDX4 0 ;;; 122.13 0.007254999999999999 15165900.0 105229.0 90682.0 102989.0 90308.0 98807.0 97071.0 88520.0 91162.0 104479.0 75098.0 False True 103728.41516336479 90472.03140048536 94521.6419690364 96949.55157865655 92995.36652203623 92919.4996135531 93103.13246831356 95397.719323243 92711.47480735551 88078.58923820483 1.1776802519263299 1.0271739384449898 1.0731511799468836 1.100716444452358 1.055822616215323 1.0549612614963237 1.0570461365646997 1.0830977215727637 1.0525994524801168 1.0 16.426503740875148 -1.5229002382994759 0.009630405302948626 2.261160571055798e-06 2.2712664486293037 0.3819276778124556 0.03543928419268957 16112.603165092622 12.0413568473106 1230.6888244915424 1635.8259724681607 0.029998515351573423 1.5229002382994759 2.2712641874687325 YLY(ph)PNIDK ddPTM_PC-9_Lapatinib_30min_R1 1 YLYPNIDK 8 0 A0A669KB68;A0A669KB56;A0A669KBA4;A0A669KB53;P42224;J3KPM9;A0A669KBI6;P42224-2 A0A669KB68 STAT1 Signal transducer and activator of transcription 1-alpha/beta;Signal transducer and activator of transcription 1 Y(0.001)LY(0.999)PNIDK 79.116 0.036851 0.0 14080.0 15358.0 19295.0 10717.0 13694.0 17051.0 9727.5 7967.2 20076.0 6190.7 True False 13879.216618044235 15322.439494592707 17708.639580853895 11505.163930863971 12888.545843439868 16321.768477822361 10231.142352976949 8337.385197693562 17814.8294703478 7260.754246410763 1.911539235046442 2.110309614482147 2.4389531693085296 1.5845687018743768 1.7750973805250485 2.2479439358370743 1.4091018654204623 1.1482808692795263 2.4535783564296056 1.0 12.825903707681478 -10.904796542291455 0.13213077796248188 8.05323602116752e-12 2.389156997016119 0.300161175304687 0.4105774700032931 50.71762625701565 1.1852345723514155 21.856268792032466 3.9983447392324556 1.2450977769319067e-11 10.904796542291455 2.3891569970080657 YLYSSEDYIK ddPTM_PC-9_Lapatinib_30min_R1 1 YLYSSEDYIK 10 0 Q13200;Q13200-3;Q13200-2 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 0 115.71 0.005072699999999999 4087000.0 16766.0 20426.0 20718.0 26454.0 24479.0 20896.0 20475.0 19822.0 18598.0 23025.0 False True 16526.913765492154 20378.7048519697 19014.64601379274 28399.51540795704 23039.193347565677 20002.326790955143 21535.095315055583 20743.002483768687 16503.297394377783 27004.840571116 0.6119981979515594 0.7546315557132551 0.7041199137509643 1.0516453645844799 0.8531505041436191 0.7406941262356258 0.7974531550498847 0.7681216420864603 0.6111236743248719 1.0 14.720930410604053 -4.824483120458154 1.6950077565239505 0.8144841621019536 0.5607634493713631 0.2058932983682379 0.12341839449888502 1.5160249658460132 4.65882936687218 0.03500478537165025 0.6173585001209834 1.4980174747315963e-05 4.824483120458154 -0.2537207127305905 YMACCLLYR ddPTM_PC-9_Lapatinib_30min_R1 4 YMACCLLYR 9 0 Q9BQE3;F5H5D3;A0A1W2PQM2;A6NHL2-2;A6NHL2;P68363;P68363-2;P68366-2;P68366;Q71U36-2;Q71U36 Q9BQE3;P68363;P68366-2;Q71U36-2 TUBA1C;TUBAL3;TUBA1B;TUBA4A;TUBA1A Tubulin alpha-1C chain;Tubulin alpha chain-like 3;Tubulin alpha-1B chain;Tubulin alpha-4A chain;Tubulin alpha-1A chain 0 ;;; 148.21 0.0015627 83154000.0 131499.0 147468.0 168298.0 129614.0 150408.0 156786.0 127954.0 140023.0 142733.0 132791.4 False True 129623.80014603712 147126.546906407 154461.18808906685 139146.24593962904 141561.2971535054 150080.62826601704 134578.8320362696 146528.9797590932 126656.90649487694 155744.2165565814 0.8322864438368739 0.9446678031409041 0.9917619511280636 0.89342801303365 0.9089345356337942 0.9636353219671127 0.8641016341520297 0.9408309534618234 0.8132366600519183 1.0 17.24881906529407 -7.266265744295809 24.895222021495485 0.8996115633579704 0.9246788405424325 0.017225652899747645 0.06056122409179953 1564.4283467923108 8069515.667502402 0.023812086039248486 0.016600469106591506 5.4166934212522826e-08 7.266265744295809 0.02506727718446211 YMEDS(ph)TYYK ddPTM_PC-9_AZD4547_30min_R2 1 YMEDSTYYK 9 0 H0YBP1;E7ESA6;Q05397-7;Q05397;Q05397-5;E9PEI4;H0YB16;H0YBZ1;Q05397-2;Q05397-4;Q05397-3 H0YBP1 PTK2 Focal adhesion kinase 1 1 YMEDS(0.495)T(0.495)Y(0.008)Y(0.001)K 127.56 0.001196 35472000.0 144430.0 147800.0 139080.0 183930.0 177270.0 164570.0 130800.0 119470.0 121710.0 144270.0 True False 190355.73566937578 195573.459613471 137235.7083267423 141527.78019017255 152659.12040293412 154279.41188428437 142440.94660682438 101008.656647486 128143.34212411022 139219.15121237005 1.3673099858150988 1.404788478527182 0.985753088793063 1.016582696832283 1.0965382210243635 1.1081766448133334 1.0231418979816913 0.7255370814134878 0.9204433514225038 1.0 17.086998158745985 -1.6736371217370414 0.3580544954440891 0.9076104889727937 6.823014866786879 0.6316846925824322 0.11521947961860038 37.1763840010018 0.577401545125864 0.10167046220596433 147.2052277756038 0.02120131888689652 1.6736371217370414 5.9154043778140855 YMEDS(ph)TYYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YMEDSTYYK 9 0 H0YBP1;E7ESA6;Q05397-7;Q05397;Q05397-5;E9PEI4;H0YB16;H0YBZ1;Q05397-2;Q05397-4;Q05397-3 H0YBP1 PTK2 Focal adhesion kinase 1 1 YMEDS(0.473)T(0.473)Y(0.047)Y(0.008)K;YMEDS(0.487)T(0.487)Y(0.025)Y(0.002)K 93.162 0.0056966000000000004 13915900.0 98560.0 91686.0 61504.0 76177.0 96988.0 67978.0 71680.0 57926.0 69889.0 55304.0 True False 115244.2613512671 100787.98014833526 62970.48861521887 71909.04965916633 77983.89763418368 64413.1140115703 64889.95148174055 56405.50387767028 70910.99440800217 65330.177413776866 1.7640279869646323 1.5427476877949062 0.9638805695626294 1.1007018885578919 1.1936887472425322 0.9859626371990661 0.9932615224776126 0.8633912551686329 1.0854247947143707 1.0 15.995461937145977 -5.135277122043194 3.332173879316988 1.0237820882837765 1.732725084914664 0.8940010662202257 0.08799832196805676 0.07583589607787018 1.523554460131805 0.02481414839461678 0.08489348095110762 7.323570690996355e-06 5.135277122043194 0.7089429966308876 YMEDS(ph)TYYK ddPTM_PC-9_Lapatinib_30min_R1 4 YMEDSTYYK 9 0 H0YBP1;E7ESA6;Q05397-7;Q05397;Q05397-5;E9PEI4;H0YB16;H0YBZ1;Q05397-2;Q05397-4;Q05397-3 H0YBP1 PTK2 Focal adhesion kinase 1 1 YMEDS(0.422)T(0.422)Y(0.156)YK;YMEDS(0.343)T(0.343)Y(0.308)Y(0.005)K;YMEDS(0.363)T(0.363)Y(0.231)Y(0.044)K;YMEDS(0.323)T(0.323)Y(0.323)Y(0.032)K 126.52 0.0012255 77054900.0 409687.0 390567.0 337334.0 272696.0 337237.0 379818.0 358223.0 325282.0 342594.0 275249.0 True False 403844.7882526049 389662.6661078658 309599.7006668967 292750.9735271889 317401.3826934516 363574.06953900284 376770.03414139914 340395.7892203239 304007.4560452449 322825.4229037611 1.2509695940923364 1.207038350954255 0.9590313485291796 0.9068398978430585 0.9831982247199704 1.1262250236326323 1.167101496382829 1.0544268358994786 0.9417085349435874 1.0 18.30039467155605 -5.169105049117114 5.512970611199608 1.0236299762080892 1.237616026266991 0.5474702822927324 0.07702969032241398 0.19257031311748263 8.97473755080324 0.02256780648247588 0.06260293823768938 6.774776164345228e-06 5.169105049117114 0.21398605005890192 YMEDST(ph)YYK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YMEDSTYYK 9 0 H0YBP1;E7ESA6;Q05397-7;Q05397;Q05397-5;E9PEI4;H0YB16;H0YBZ1;Q05397-2;Q05397-4;Q05397-3 H0YBP1 PTK2 Focal adhesion kinase 1 1 YMEDS(0.153)T(0.824)Y(0.023)YK 108.74 0.0092262 24521000.0 120060.0 104590.0 75815.0 108050.0 118690.0 94463.0 116540.0 81712.0 90075.0 85390.0 True False 140383.78670691035 114973.00398877027 77622.71712998861 101996.30880282639 95433.54652329392 89509.1939873924 105500.48752346593 79567.14658102047 91392.1764698418 100870.53105313185 1.3917224906148808 1.1398076602591711 0.7695281894481367 1.0111606208269246 0.9460993763681674 0.8873671334221978 1.0458999910280569 0.788804676155713 0.9060344534292429 1.0 16.622145232496962 -4.956533582966721 3.442602442529568 0.9196514348332511 1.3843805385643464 0.7462271113448165 0.08668103177793295 0.11417435026234656 2.6463216151888123 0.021425086109180938 0.1105483891731607 1.1052649985459458e-05 4.956533582966721 0.4647291037310953 YMEDSTY(ph)YK ddPTM_PC-9_AZD4547_30min_R2 2 YMEDSTYYK 9 0 H0YBP1;E7ESA6;Q05397-7;Q05397;Q05397-5;E9PEI4;H0YB16;H0YBZ1;Q05397-2;Q05397-4;Q05397-3 H0YBP1 PTK2 Focal adhesion kinase 1 1 YMEDS(0.057)T(0.017)Y(0.831)Y(0.094)K;YMEDS(0.134)T(0.134)Y(0.723)Y(0.009)K 116.05 0.0020353999999999997 49450400.0 157882.0 186464.0 157560.0 233801.0 206840.0 215580.0 150933.0 159422.0 159045.0 186972.0 True False 208085.1918503934 246734.8414977416 155470.6514521249 179901.7916394419 178123.83631828788 202099.74852047217 164365.74460403595 134786.99305311346 167451.79400319714 180426.1671898472 1.1532982997496308 1.3675114055830015 0.8616857181726655 0.9970936834796609 0.9872394846744331 1.1201243792305342 0.9109861788012588 0.7470479207779684 0.9280904018040895 1.0 17.461049062128566 -5.264213664426818 24.99826961943573 0.9435462445737991 1.2604048611191248 0.5956782534445622 0.1042586838244545 157.6090333860512 1420182.8947807422 0.028702024524399065 0.06434313199219037 5.442348340281271e-06 5.264213664426818 0.31685861654532566 YMEDSTY(ph)YK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YMEDSTYYK 9 0 H0YBP1;E7ESA6;Q05397-7;Q05397;Q05397-5;E9PEI4;H0YB16;H0YBZ1;Q05397-2;Q05397-4;Q05397-3 H0YBP1 PTK2 Focal adhesion kinase 1 1 YMEDS(0.389)T(0.106)Y(0.428)Y(0.078)K 117.81 0.0019241 8274700.0 51249.0 52445.0 46156.0 48530.0 53216.0 40611.0 54042.0 37162.0 37572.0 38333.0 True False 59924.44348611077 57651.39300306972 47256.53408760475 45811.02143638281 42788.70681425239 38481.28766842041 48922.75052980217 36186.53687639373 38121.4194207594 45282.46945613898 1.3233475162867199 1.273150375752175 1.0435944562029214 1.0116723311822866 0.9449287401540222 0.8498054132337846 1.080390515742283 0.7991290517281604 0.8418582263426283 1.0 15.466665016495291 -5.259319588344551 1.0106553952359232 0.9101046847593874 1.4159502541434177 0.7738951769710252 0.07896745715181687 0.4530296732716512 0.6167662725357658 0.027693381135499927 0.21013017894117783 5.5040251749104285e-06 5.259319588344551 0.5058455693840302 YMEDSTY(ph)YK ddPTM_PC-9_Lapatinib_30min_R1 1 YMEDSTYYK 9 0 H0YBP1;E7ESA6;Q05397-7;Q05397;Q05397-5;E9PEI4;H0YB16;H0YBZ1;Q05397-2;Q05397-4;Q05397-3 H0YBP1 PTK2 Focal adhesion kinase 1 1 YMEDS(0.029)T(0.092)Y(0.788)Y(0.092)K 154.49 9.4351e-05 19592000.0 78816.0 69690.0 74822.0 54710.0 61349.0 74260.0 61190.0 57660.0 64421.0 51411.0 True False 77692.0693869156 69528.63708674081 68670.4239812723 58733.55590720982 57740.57243677472 71084.07290851488 64358.11879503058 60339.094098178924 57165.22859679595 60297.322849148535 1.28848289966845 1.1530965854103858 1.138863563695382 0.9740657318095044 0.9575976131018241 1.1788926862698792 1.0673462063322665 1.0006927546208793 0.9480558322599423 1.0 15.879806328640024 -5.0114119018933305 1.267664915742411 1.0258370784611583 1.333483921027626 0.606732231781894 0.06802147335799531 0.7253267702689142 1.3543419625744462 0.022323553411393367 0.26213531958790964 9.740653577459516e-06 5.0114119018933305 0.30764684256646757 YMIGVTYGGDDIPLSPYR ddPTM_PC-9_Lapatinib_30min_R1 1 YMIGVTYGGDDIPLSPYR 18 0 O75369-2;O75369-9;O75369;O75369-8;O75369-6;O75369-3;E7EN95;O75369-7;O75369-5;O75369-4 O75369-2 FLNB Filamin-B 0 162.93 4.2942e-06 2561700.0 4318.1 6306.2 6211.5 4490.0 4356.5 5086.8 3989.0 2894.2 3930.6 4726.7 False True 4256.523102157443 6291.598381351774 5700.81444708339 4820.209578200919 4100.259235208545 4869.249421909959 4195.530901673098 3028.6750977965535 3487.8944369470532 5543.703797068141 0.7678121447268809 1.1349088284044264 1.0283403759952576 0.8694926270682335 0.7396245155408591 0.8783386703461905 0.7568100777483744 0.5463270060349016 0.6291632029098796 1.0 12.436634460261866 -6.04902822781736 2.731029763620872 0.7403784758791042 0.9919849875591473 0.3077115913904216 0.1448426115323119 0.3047397884097539 4.514485255444832 0.045598333974603396 0.06598010307394643 8.932474234870185e-07 6.04902822781736 0.2516065116800431 YMLTHQELAS(ph)DGEIETK ddPTM_PC-9_AZD4547_30min_R2 7 YMLTHQELASDGEIETK 17 0 Q02241;H7BYN4;A0A2U3TZL8;Q02241-2;Q02241-3 Q02241;Q02241-2 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 YMLTHQELAS(0.999)DGEIET(0.001)K;YMLTHQELAS(1)DGEIETK;YMLTHQELAS(1)DGEIETK;YMLT(0.001)HQELAS(0.998)DGEIET(0.001)K;YMLTHQELAS(0.996)DGEIET(0.004)K;Y(0.004)MLT(0.07)HQELAS(0.922)DGEIET(0.004)K;YMLTHQELAS(1)DGEIETK 129.84 2.0378e-05 196580400.0 429563.0 440065.0 527624.0 612002.0 502144.0 516912.0 469336.0 598102.0 469551.0 479254.0 True False 566155.0985345414 582307.4053098924 520627.3610166026 470914.39423664415 432429.97323636775 484589.4109250122 511105.9947756928 505679.0789166708 494370.50725263404 462475.4633335647 1.2241840776884565 1.2591098371199376 1.125740503645045 1.0182473051483658 0.9350333315401722 1.0478164775100676 1.1051526735961188 1.0934181789271382 1.0689659159194458 1.0 18.819017299814917 -5.469252051059663 3.268919332909447 1.041708375810791 1.240587719892519 0.7463002366041415 0.047130952954201194 0.13515627217586237 2.848113014773211 0.01472551991092603 0.032700938850500794 3.394282217929023e-06 5.469252051059663 0.19887934408172803 YMLTHQELAS(ph)DGEIETK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 YMLTHQELASDGEIETK 17 0 Q02241;H7BYN4;A0A2U3TZL8;Q02241-2;Q02241-3 Q02241;Q02241-2 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 YMLTHQELAS(1)DGEIETK;YMLTHQELAS(1)DGEIETK;YMLTHQELAS(0.996)DGEIET(0.004)K;YMLTHQELAS(1)DGEIETK;YMLT(0.01)HQELAS(0.986)DGEIET(0.004)K 103.4 0.00060242 74914300.0 240525.0 235896.0 208395.0 259403.0 300188.0 273610.0 269605.0 265010.0 231717.0 208500.0 True False 281241.13191470655 259314.19589764753 213363.92714243822 244869.49090587252 241368.31631758812 259261.4099371231 244066.06262883107 258053.7683013055 235105.42275950479 246299.3995149086 1.1418669004821627 1.0528413646495762 0.8662787142910724 0.9941944291709508 0.97997931295394 1.0526270484123932 0.9909324306495423 1.0477239035480694 0.9545513437001854 1.0 17.91005358494555 -4.963297589244461 5.207901808616894 0.9882221587293831 1.127828966987803 0.49135652859155343 0.04929459823432675 0.15895802313093835 10.76111581411866 0.012588439554621016 0.05189390091208952 1.0881841872771526e-05 4.963297589244461 0.13960680825841987 YMLTHQELAS(ph)DGEIETK ddPTM_PC-9_Lapatinib_30min_R1 6 YMLTHQELASDGEIETK 17 0 Q02241;H7BYN4;A0A2U3TZL8;Q02241-2;Q02241-3 Q02241;Q02241-2 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 YMLTHQELAS(1)DGEIETK;YMLTHQELAS(1)DGEIETK;YMLTHQELAS(0.999)DGEIET(0.001)K;YMLTHQELAS(1)DGEIETK;YMLTHQELAS(0.999)DGEIET(0.001)K;YMLTHQELAS(0.996)DGEIET(0.004)K 110.33 0.00022645 154573000.0 855397.0 815431.0 597583.0 528183.0 612449.0 604695.0 515100.0 466743.0 619471.0 491360.0 True False 843198.8819194024 813542.9196194306 548452.0324770869 567027.3397868371 576425.9539410624 578833.6044628933 541769.3575963435 488429.58370909333 549699.652661179 576290.9213039562 1.4631479531406144 1.411687898498646 0.9516929942885807 0.9839255119685755 1.0002343133166156 1.0044121520311025 0.9400969849924031 0.847539958817915 0.9538579081159044 1.0 19.136437766601233 -5.245625151878972 5.435879355654455 0.9569765783806273 1.4456760209276818 0.9484388825725919 0.044530537978065145 0.035392998375510645 3.611507983541061 0.012824978663811186 0.03262667022468673 5.680346757998951e-06 5.245625151878972 0.48869944254705444 YMLTHQELASDGEIET(ph)K ddPTM_PC-9_AZD4547_30min_R2 1 YMLTHQELASDGEIETK 17 0 Q02241;H7BYN4;A0A2U3TZL8;Q02241-2;Q02241-3 Q02241;Q02241-2 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 YMLTHQELAS(0.397)DGEIET(0.603)K 90.755 0.0048903 4521600.0 25143.0 21304.0 28213.0 33688.0 23037.0 27822.0 30291.0 32487.0 30274.0 28178.0 True False 33137.95099311157 28190.10137757364 27838.877185953264 25921.75207441163 19838.710197565284 26082.285941815386 32986.84031855751 27466.88062699314 31874.22183440405 27191.496796715684 1.21868800532945 1.036724884559447 1.0238081924683078 0.9533036106178083 0.7295924290553029 0.9592074366779885 1.213130728520315 1.0101275715837283 1.1722128455339011 1.0 14.730867948409863 -9.397552419833232 13.43408355421801 0.9999999999999998 1.0257729990153452 0.0016438154753436462 0.1383972713394067 0.0 0.0 0.14280391812727253 0.03463503754063538 4.003571418560195e-10 9.397552419833232 0.025772999015345466 YMNSDTT(ph)SPELR ddPTM_PC-9_AZD4547_30min_R2 1 YMNSDTTSPELR 12 0 Q96ST3 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 YMNSDT(0.001)T(0.499)S(0.499)PELR 120.6 0.0011788 0.0 12557.0 15464.0 21611.0 23957.0 24348.0 22540.0 15175.0 25088.0 16975.0 19225.0 True False 16549.864798174523 20462.43558499806 21324.424019623453 18434.083781960333 20967.70047707252 21130.570236809683 16525.545602129692 21211.226064887614 17872.26384485065 18551.93860163459 0.8920827711620571 1.1029809889083582 1.1494445123780532 0.9936473043488905 1.1302161422216588 1.1389952656995046 0.890771900283976 1.1433428344258707 0.9633636801318407 1.0 14.179282329998317 -8.310196485304076 24.994157598129224 0.9816817522921093 1.0576834764314418 0.08740294968076723 0.09472956005005866 1094.7620297399299 561193.9966641886 0.08769285595494844 0.0226422479474831 4.895572817294106e-09 8.310196485304076 0.07600172413933248 YMNSDTT(ph)SPELR ddPTM_PC-9_Lapatinib_30min_R1 1 YMNSDTTSPELR 12 0 Q96ST3 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 YMNS(0.035)DT(0.069)T(0.448)S(0.448)PELR 80.87100000000001 0.033796 20144000.0 37300.0 45308.0 49988.0 42750.0 58762.0 53718.0 43257.0 57028.0 52689.0 42048.0 True False 36768.09516001774 45203.09210971521 45878.179599260155 45893.977609819405 55305.73469053699 51420.606362774095 45496.635801873475 59677.72907094949 46754.60998023283 49315.94077456182 0.7455620755182568 0.9166020438777048 0.930291075840635 0.9306114187218845 1.12145756163015 1.042677186223281 0.9225543523513512 1.210110324038115 0.9480628219983146 1.0 15.589766435060323 -3.8013600697970946 0.5914569304904906 1.0457049252467465 1.748512323775004e-16 0.5175674399878794 0.0837522236309313 8.17781917344257 0.9058372511135481 0.03870276039989885 7.572728791029978 0.0001579937583522031 3.8013600697970946 -1.0457049252467463 YMNSDTTS(ph)PELR ddPTM_PC-9_AZD4547_30min_R2 1 YMNSDTTSPELR 12 0 Q96ST3 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 YMNS(0.028)DT(0.028)T(0.087)S(0.856)PELR 81.904 0.011179999999999999 37304000.0 54642.0 43070.0 56061.0 73964.0 60743.0 53634.0 55245.0 61725.0 54326.0 56100.0 True False 72017.01937579447 56991.53522024485 55317.59451039329 56912.742532408614 52309.88295050173 50280.25750137756 60161.697976254 52186.81954939371 57197.56145127283 54135.956075511014 1.330299205861299 1.0527482906323988 1.0218272386883511 1.0512928312012155 0.9662687563426015 0.9287774918252968 1.111307573331448 0.9639955277893574 1.056554009529108 1.0 15.724299502645282 -4.739859667398587 3.1892079019992616 1.0121199027000383 1.3957416041080188 0.782074982026866 0.05000603999723824 0.18284487680292388 2.57961363131648 0.012481649828989166 0.18627803974172158 1.8202889494742764e-05 4.739859667398587 0.3836217014079806 YMNSDTTS(ph)PELR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YMNSDTTSPELR 12 0 Q96ST3 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 YMNS(0.099)DT(0.099)T(0.305)S(0.498)PELR;YMNS(0.015)DT(0.01)T(0.14)S(0.835)PELR 71.976 0.023005 55182000.0 155574.0 167666.0 168718.0 177547.0 214635.0 165974.0 167918.0 149114.0 161455.0 127749.0 True False 181909.60547343793 184310.7724140084 172740.87698657773 167599.61720514056 172578.81252023968 157270.03125947178 152011.59141895804 145199.91549934293 163815.97393214953 150908.88243947268 1.2054267617176158 1.221338130894533 1.1446700432352717 1.1106014072588621 1.1435961205892469 1.0421522492060762 1.0073071177896213 0.9621694439197803 1.0855290376817528 1.0 17.203318199282442 -6.238162044221504 0.6920985611046685 1.0028279506146398 1.223315360303709 0.7985253463532034 0.0376600795438433 0.354632363311142 0.3611707499339782 0.02383422153662748 0.04510612181279201 5.778803880925109e-07 6.238162044221504 0.2204874096890692 YMNSDTTS(ph)PELR ddPTM_PC-9_Lapatinib_30min_R1 3 YMNSDTTSPELR 12 0 Q96ST3 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 YMNS(0.006)DT(0.002)T(0.137)S(0.855)PELR;YMNS(0.001)DT(0.004)T(0.044)S(0.951)PELR;YMNS(0.001)DT(0.006)T(0.024)S(0.97)PELR 133.15 6.6247e-05 55646000.0 209386.0 219363.0 210709.0 168569.0 216165.0 223592.0 210833.0 221005.0 213122.0 165844.0 True False 206400.11724330997 218855.07845112248 193385.3193802618 180966.12658969907 203450.59969674164 214029.49137840906 221748.90112620805 231273.69911841938 189117.956085847 194509.9144267605 1.0611290321708848 1.125161558453766 0.9942183150416112 0.930369678702619 1.0459651904959715 1.1003526067510474 1.140039065770624 1.1890072534348972 0.9722792621815494 1.0 17.569484167590595 -6.674478241333371 5.001422908397776 1.09578055548904 1.0275060693072713 0.08107181811908837 0.075099945109976 0.4255854629433474 18.170390787559565 0.026210852876736034 0.025947085545428555 2.1160296981730438e-07 6.674478241333371 -0.06827448618176879 YMS(ph)FTDK ddPTM_PC-9_AZD4547_30min_R2 2 YMSFTDK 7 0 H0YCM0;E9PM17;B3KNX7;Q13153;Q13153-2 H0YCM0 PAK1 Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase PAK 1 1 Y(0.005)MS(0.99)FT(0.005)DK;Y(0.004)MS(0.985)FT(0.01)DK 81.97200000000001 0.023162000000000002 12625600.0 76487.0 82529.0 91654.0 103743.0 84437.0 105822.0 106717.0 100138.0 99674.0 97217.0 True False 100808.27497156749 109204.88530744358 90438.60807434018 79826.65416337222 72714.38003871244 99204.93361134337 116214.60626177746 84663.97304231979 104942.564151496 93813.46242055179 1.0745608612083732 1.1640641171295258 0.9640259056735094 0.8509083036027517 0.7750953665130138 1.057470122642126 1.238783893731634 0.9024714668645721 1.1186301138855115 1.0 16.51750734678628 -9.253550377395877 15.927380249322459 0.9999994357779197 1.0114955773503012 0.00018959387506001235 0.1372292951324696 0.0 0.0 0.14246742545512206 0.03455342608007521 5.577628988735045e-10 9.253550377395877 0.011496141572381435 YMS(ph)FTDK ddPTM_PC-9_Lapatinib_30min_R1 2 YMSFTDK 7 0 H0YCM0;E9PM17;B3KNX7;Q13153;Q13153-2 H0YCM0 PAK1 Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase PAK 1 1 Y(0.194)MS(0.799)FT(0.007)DK;Y(0.004)MS(0.979)FT(0.017)DK 78.939 0.027598 37474000.0 162100.0 219898.0 192860.0 175917.0 220323.0 241753.0 212804.0 216634.0 217933.0 140707.0 True False 159788.42427450107 219388.83969149244 177003.79526112878 188854.52302190888 207364.03431168414 231413.78774376784 223821.94986203103 226699.6065012989 193387.09060377075 165028.0174697079 0.9682502809187016 1.3294035949487357 1.0725681491848444 1.1443785480642674 1.256538359310699 1.4022696951215907 1.3562663679403115 1.3737037502914393 1.1718439909106244 1.0 17.332351451836523 -6.320137516980429 4.172527394249273 1.293226263001901 1.1382610558551642 0.15540356276221168 0.13898614712356241 0.3475596115471277 12.444593223973405 0.042041495417869265 0.049043657524749894 4.784785607049324e-07 6.320137516980429 -0.15496520714673667 YMS(ph)QMSVPEQAELEK ddPTM_PC-9_Lapatinib_30min_R1 1 YMSQMSVPEQAELEK 15 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154;E9PGW9;E7EV93;E5RGQ4;Q15154-3 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 Y(0.055)MS(0.493)QMS(0.452)VPEQAELEK 69.815 0.014934999999999999 25965000.0 69097.0 71341.0 63350.0 43146.0 87890.0 82680.0 98154.0 91758.0 85322.0 94448.0 True False 68111.66410916217 71175.81429767782 58141.60753807176 46319.10077083669 82720.48299838837 79143.96913649366 103235.93384878944 96021.41165904794 75712.13787950852 110773.21095595088 0.6148748738198703 0.6425363468608035 0.5248706527175767 0.41814352379164615 0.7467553055881199 0.7144684933613179 0.9319575821435866 0.866828819264172 0.6834877966082933 1.0 16.757249501185562 -6.678017528240393 2.0179188676270488 0.8510278403908251 0.55857964945017 0.6308346309171915 0.10398390467847567 0.21952848493872365 1.8355612112444746 0.04062800910267769 0.03951828671256664 2.0988551715630386e-07 6.678017528240393 -0.2924481909406551 YMSQMS(ph)VPEQAELEK ddPTM_PC-9_AZD4547_30min_R2 6 YMSQMSVPEQAELEK 15 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154;E9PGW9;E7EV93;E5RGQ4;Q15154-3 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 Y(0.001)MS(0.037)QMS(0.962)VPEQAELEK;YMS(0.003)QMS(0.997)VPEQAELEK;Y(0.01)MS(0.019)QMS(0.97)VPEQAELEK;YMSQMS(1)VPEQAELEK;Y(0.002)MS(0.003)QMS(0.994)VPEQAELEK;Y(0.003)MS(0.008)QMS(0.989)VPEQAELEK 102.36 0.00089339 130233800.0 278520.0 265628.0 317015.0 448677.0 340683.0 339742.0 429938.0 526564.0 447280.0 379124.0 True False 367083.56642411207 351487.0563613465 312811.1739660788 345241.4496405479 293385.0460666373 318497.87903257326 468201.6490997329 445195.63303696876 470922.3076597817 365850.9841563654 1.0033690828264108 0.9607383103584062 0.8550234590386744 0.9436668605297261 0.8019249879651656 0.8705672331783223 1.2797605292203413 1.2168769589716104 1.2871970503119068 1.0 18.480896614214842 -7.257711304574894 24.999583216341748 1.2140317206676905 0.9030556016671929 0.7045430707646192 0.09171721596008038 164.84708915841088 1105429.4704152148 0.03517589447661629 0.026169701562862375 5.524445524349449e-08 7.257711304574894 -0.3109761190004976 YMSQMS(ph)VPEQAELEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 YMSQMSVPEQAELEK 15 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154;E9PGW9;E7EV93;E5RGQ4;Q15154-3 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 Y(0.003)MS(0.017)QMS(0.98)VPEQAELEK;YMS(0.002)QMS(0.998)VPEQAELEK;Y(0.003)MS(0.029)QMS(0.968)VPEQAELEK;Y(0.001)MS(0.009)QMS(0.99)VPEQAELEK;YMS(0.002)QMS(0.998)VPEQAELEK 94.639 0.0017893 86757000.0 253219.0 236554.0 179090.0 266356.0 286400.0 286297.0 338364.0 381594.0 315846.0 272543.0 True False 296083.97539677814 260037.51778907707 183360.1848026075 251432.93685780352 230281.97593960285 271283.08132293617 306311.7123767807 371577.56183226424 320464.65022807254 321952.8884507992 0.9196500047615682 0.8076881031890973 0.569524894418298 0.780961891870796 0.7152660659380744 0.8426173240076198 0.9514178110055727 1.1541364440625252 0.9953774658463606 1.0 18.296490067835627 -7.269919794559118 2.248484251529186 1.0552082549450248 0.7536377636041319 0.6496798088768732 0.09341579797291881 0.191743125037825 1.8989167702513834 0.04677028688635954 0.030295663947322218 5.3713098448196324e-08 7.269919794559118 -0.30157049134089287 YMSQMS(ph)VPEQAELEK ddPTM_PC-9_Lapatinib_30min_R1 6 YMSQMSVPEQAELEK 15 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154;E9PGW9;E7EV93;E5RGQ4;Q15154-3 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 YMSQMS(1)VPEQAELEK;YMS(0.003)QMS(0.997)VPEQAELEK;Y(0.002)MS(0.026)QMS(0.973)VPEQAELEK;YMS(0.003)QMS(0.997)VPEQAELEK;Y(0.001)MS(0.004)QMS(0.995)VPEQAELEK;Y(0.014)MS(0.142)QMS(0.844)VPEQAELEK 118.5 9.852299999999999e-05 63655400.0 235531.0 226584.0 187745.0 177473.0 301858.0 248068.0 335086.0 271296.0 284653.0 257550.0 True False 232172.28474890473 226059.35866927975 172309.33081665795 190524.95645257228 284103.3059156621 237458.70991475217 352435.11349161 283901.40257474076 252592.38161102385 302067.1743361965 0.7686114363770631 0.7483744606346364 0.5704338155753399 0.6307370434118098 0.9405302199419362 0.7861122627328714 1.1667441663136646 0.9398618145073999 0.8362126145156444 1.0 18.204509889236007 -6.268343757027062 23.932071728124377 0.9450550978683128 0.6766627484319583 0.5923022648377748 0.10784842876700695 219.9049517679407 762237.0820493237 0.034403877427850844 0.039903761927623606 5.390837527390481e-07 6.268343757027062 -0.2683923494363545 YNAPTSHVT(ph)PSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YNAPTSHVTPSVK 13 0 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 YNAPTSHVT(0.98)PS(0.02)VK 83.25200000000001 0.020135 5576900.0 42566.0 56035.0 55764.0 61293.0 72560.0 57495.0 64874.0 53070.0 49552.0 45891.0 True False 49771.58308317806 61597.784477586276 57093.625246147676 57858.9519245871 58342.38887631826 54479.860985837135 58728.665072913434 51676.968732312984 50276.604256826045 54210.67502704386 0.9181140625596106 1.136266693725124 1.0531804892240433 1.0672981270888666 1.0762158716380719 1.0049655526085775 1.08334133532954 0.9532618567566832 0.9274299615665137 1.0 15.726289350909669 -7.772289069519207 24.88623799523422 0.9552593798609621 1.0521566582141864 0.3371082540592003 0.05641874902649203 209.68464479456645 480951.3234010258 0.028581872813937977 0.01394864126867392 1.6893161364232657e-08 7.772289069519207 0.09689727835322426 YNAPTSHVT(ph)PSVK ddPTM_PC-9_Lapatinib_30min_R1 2 YNAPTSHVTPSVK 13 0 O60271;O60271-3;A0A087X2D8;O60271-4;O60271-2;O60271-5;O60271-9 O60271 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 YNAPTS(0.001)HVT(0.975)PS(0.024)VK;YNAPTS(0.001)HVT(0.956)PS(0.043)VK 81.594 0.024031 14848700.0 218800.0 157320.0 197463.0 192212.0 159384.0 149993.0 118565.0 109218.0 167747.0 96078.0 True False 215679.87187699435 156955.73520571238 181228.35436922236 206347.91168043495 150009.34648100048 143578.1490407605 124703.7155569996 114292.66699991134 148853.56640577974 112684.95428411198 1.9140077151134287 1.3928721558512658 1.6082746407501063 1.8311931081781427 1.3312278239274313 1.274155453608808 1.1066580835857178 1.0142673236725626 1.320971085726991 1.0 16.781935373897667 -6.584368761263271 2.177370289229763 1.1279796269442741 1.6591037748243376 0.7110126706999449 0.16225098387525108 0.1754145620170646 1.6881415661276087 0.05875811934092782 0.06079211015155538 2.6039415933295856e-07 6.584368761263271 0.5311241478800635 YNDWS(ph)DDDDDSNESK ddPTM_PC-9_Lapatinib_30min_R1 2 YNDWSDDDDDSNESK 15 0 Q9UH62;H3BV87 Q9UH62 ARMCX3 Armadillo repeat-containing X-linked protein 3 1 YNDWS(1)DDDDDSNESK;YNDWS(0.942)DDDDDS(0.057)NES(0.001)K 165.66 0.00012316 8346700.0 68122.0 66050.0 44166.0 38929.0 44879.0 38109.0 39402.0 37658.0 44337.0 28222.4 True False 67150.56778795511 65897.06528310005 40534.84196569021 41791.968523337084 42239.30545550885 36479.16690641794 41442.04276453332 39407.72815728789 39343.30017069189 33100.60423601583 2.028681026761755 1.9908115517540708 1.2245952272250484 1.2625741882338337 1.2760886524708652 1.1020695165052603 1.2520026060261886 1.19054407213538 1.1885976428153404 1.0 15.014569932544088 -5.2609698767625686 5.300172259993473 1.1965796155920922 2.0212694779581515 0.9462996936169951 0.07841712424849696 0.030240916706161212 3.0100440511653996 0.01951728217073412 0.047729024352559116 5.4831499545238355e-06 5.2609698767625686 0.8246898623660592 YNEQHVPGSPFTAR ddPTM_PC-9_Lapatinib_30min_R1 1 YNEQHVPGSPFTAR 14 0 Q60FE5;P21333-2;P21333;A0A087WWY3 Q60FE5 FLNA Filamin-A 0 69.878 0.02408 12921000.0 87944.0 73110.0 90793.0 79319.0 103750.0 104090.0 86459.0 68550.0 95217.0 73052.0 False True 86689.90243304557 72940.71828686491 83328.35001111522 85152.38386042716 97647.62898034806 99638.31334564122 90935.42397286407 71735.08325407842 84492.65878053932 85678.94086432869 1.0117994172023872 0.8513260966001603 0.9725651270954015 0.9938543007349341 1.1396922977254307 1.1629265294422464 1.061350934728044 0.8372545520569616 0.9861543330038611 1.0 16.38665302561305 -4.420106767300715 21.546918862825343 1.0013571412952598 2.724042005964651 0.0010845346604166917 0.09969842129606284 12243.583652431775 2676429.1573481616 0.02692396321993687 44352.515390967324 3.80095941745046e-05 4.420106767300715 1.722684864669391 YNEWADDRR ddPTM_PC-9_AZD4547_30min_R2 1 YNEWADDRR 9 1 Q92620 Q92620 DHX38 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 0 81.525 0.035869 0.0 12698.0 11604.0 16656.0 22804.0 16225.0 15727.0 13561.0 15154.0 14959.0 15185.0 False True 16735.699865192324 15354.766071412158 16435.130557162927 17546.890118287905 13972.438813886207 14743.588203829006 14767.902728861995 12812.297504277234 15749.702200596226 14653.377771954289 1.1421052623937313 1.0478652983887637 1.1215933154073738 1.1974638469958532 0.9535302393301182 1.0061562892377875 1.0078156012006256 0.8743579605788384 1.0748171817927359 1.0 13.838945640316588 -6.2739550855184705 24.8812737075007 0.9819180786021801 1.1211815574823414 0.5815347967194847 0.0585001376183138 514.2575475328254 1022343.907927403 0.017787089961336128 0.02030173336684923 5.321632924377193e-07 6.2739550855184705 0.13926347888016133 YNGLIHR ddPTM_PC-9_AZD4547_30min_R2 2 YNGLIHR 7 0 P46779;H0YKD8;P46779-2;P46779-3;H0YLP6;H0YMF4;P46779-4;P46779-5 P46779 RPL28 60S ribosomal protein L28 0 ; 133.47 0.003568 11744300.0 87925.0 93834.0 118609.0 154790.0 124164.0 118962.0 114322.0 125363.0 110178.0 121352.0 False True 115883.32104638833 124164.00547611927 117036.16716225607 119105.55698166045 106925.971826648 111523.28733413293 124496.4365289401 105991.02890515422 116001.78414715503 117103.50341667436 0.9895803085758723 1.060292833719265 0.9994249851417452 1.0170964446542854 0.9130894354730537 0.9523480005317513 1.0631316134578863 0.9051055332479674 0.9905919187951259 1.0 16.837424712413046 -6.058702619252229 24.998189452792502 0.9692531742650724 1.0187259001428788 0.19520572145964699 0.0455178445823769 404.8952477723525 172421.3743705845 0.013229614780923254 0.017079396505517697 8.735693354149303e-07 6.058702619252229 0.04947272587780638 YNGLIHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 YNGLIHR 7 0 P46779;H0YKD8;P46779-2;P46779-3;H0YLP6;H0YMF4;P46779-4;P46779-5 P46779 RPL28 60S ribosomal protein L28 0 ;; 106.42 0.006106899999999999 9393000.0 98873.0 99293.0 103168.0 117953.0 142241.0 114818.0 111116.0 107259.0 106470.0 91052.0 False True 115610.24606923538 109150.152835424 105627.91638681867 111344.47581878559 114369.89713556228 108796.74195446301 100590.28806982517 104443.56490030464 108026.92232854948 107559.00683276475 1.074854161204639 1.0147932381444653 0.9820462227868227 1.0351943467821954 1.0633223614028648 1.0115074986107182 0.9352102723133665 0.9710350437011374 1.0043503143954486 1.0 16.71476881341345 -7.011483461873204 24.0085695476864 0.974967113994792 1.0308747361073582 0.44466403170009017 0.02955439227973516 325.06260156459007 679610.2163730656 0.011308787053394996 0.009292645284369247 9.739048713526386e-08 7.011483461873204 0.05590762211256628 YNGLIHR ddPTM_PC-9_Lapatinib_30min_R1 2 YNGLIHR 7 0 P46779;H0YKD8;P46779-2;P46779-3;H0YLP6;H0YMF4;P46779-4;P46779-5 P46779 RPL28 60S ribosomal protein L28 0 ; 133.47 0.003568 14099500.0 118410.0 137724.0 131755.0 129449.0 141804.0 130594.0 131191.0 126577.0 123863.0 120930.0 False True 116721.45168626541 137405.10853973756 120922.612489008 138969.11128920532 133463.36751739072 125008.79904948293 137983.428057507 132458.229512057 109912.24460478614 141832.58937090385 0.8229522721398623 0.9687837551947382 0.8525728326991581 0.9798108594477515 0.9409922508597307 0.8813827598012377 0.9728612349921147 0.9339054592429944 0.7749435097554104 1.0 17.113829538197592 -4.742892477961963 24.788788471661434 0.9211651020915874 0.8229519198093195 0.172877578198808 0.06543547737722978 2021.74404392654 2701996.3512858814 0.015448776397173479 0.5168005420066363 1.8076215991169233e-05 4.742892477961963 -0.09821318228226794 YNILGTNTIMDK ddPTM_PC-9_Lapatinib_30min_R1 1 YNILGTNTIMDK 12 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PRZ7;A0A1W2PQ74;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7;A0A1W2PQD4 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 123.95 0.0015517999999999999 3708300.0 22675.0 26350.0 27918.0 19036.0 24255.0 22396.0 24937.0 21217.0 21060.0 27284.0 False True 22351.650341914283 26288.988193939174 25622.689806596492 20435.970942234442 22828.368587164736 21438.1752876259 26228.11584232189 22202.81927646657 18688.001028368417 32000.00304635522 0.6984890066896453 0.8215308028520164 0.8007089802297659 0.6386240311487122 0.7133864504355062 0.6699429139606815 0.8196285420450689 0.6938380363371701 0.5839999765405325 1.0 14.96578442200463 -10.437438351400461 4.46746135751827 1.0000037403276145 0.7199442935576423 0.5666118229579546 0.07453761115691025 107115853.22123806 251774108.41665882 6854.869753589565 0.019115709407438175 3.6522596782012835e-11 10.437438351400461 -0.2800594467699722 YNLDAS(ph)EEEDSNK ddPTM_PC-9_AZD4547_30min_R2 4 YNLDASEEEDSNK 13 0 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 Y(0.015)NLDAS(0.985)EEEDSNK;Y(0.35)NLDAS(0.65)EEEDSNK;YNLDAS(1)EEEDSNK;YNLDAS(0.998)EEEDS(0.002)NK 202.01 1.4869000000000002e-07 35747100.0 160416.0 248783.0 143503.0 101907.0 119953.0 194529.0 213908.0 209073.0 211926.0 159828.0 True False 211424.95113991955 329197.2395332754 141600.05645680564 78413.915597455 103299.59648949752 182365.07087827616 232945.39760529573 176765.57186958907 223127.9757044963 154232.4703678572 1.370819974779977 2.1344223998235443 0.9180949777895523 0.5084137951653845 0.6697655574284678 1.182403876714938 1.5103525026195956 1.146098298548863 1.4466990976174965 1.0 17.23474700043713 -7.008169216788582 24.739031466892154 1.2963074729960093 1.1108825747128779 0.02661320201683215 0.4345934843552716 1609.2216895699912 4873250.459831269 0.1782552769187001 0.1500647283514772 9.813654931375557e-08 7.008169216788582 -0.18542489828313147 YNLDAS(ph)EEEDSNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 YNLDASEEEDSNK 13 0 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 Y(0.011)NLDAS(0.989)EEEDSNK;YNLDAS(0.996)EEEDS(0.004)NK;YNLDAS(0.978)EEEDS(0.022)NK 171.26 5.1719e-05 24199800.0 102004.0 235306.0 119479.0 101246.0 105772.0 60231.0 110761.0 60074.0 62495.0 56130.0 True False 119271.26252916633 258665.62459682173 122327.83248663097 95573.51486396091 85046.73589065517 57072.380329384345 100268.91623980281 58497.12115366436 63408.87114607578 66305.92467516435 1.7988024918358578 3.9010936935731766 1.8449004834171367 1.4414023382100434 1.2826415785211183 0.860743298717037 1.512216543710455 0.8822306821033616 0.9563077727475883 1.0 16.016850165688098 -5.560241683647498 3.238344701982475 1.1379809530660792 2.8690977418369146 0.6246590819700446 0.5247786984389058 0.13561723930233144 2.9156581708298317 0.13632888418550976 0.2751261515933831 2.752696409274085e-06 5.560241683647498 1.7311167887708354 YNLDAS(ph)EEEDSNK ddPTM_PC-9_Lapatinib_30min_R1 4 YNLDASEEEDSNK 13 0 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 Y(0.044)NLDAS(0.956)EEEDSNK;YNLDAS(1)EEEDSNK;Y(0.219)NLDAS(0.776)EEEDS(0.005)NK;Y(0.008)NLDAS(0.992)EEEDSNK 208.38 5.1445e-10 55645000.0 88875.8 273733.0 176321.0 214298.0 277896.0 217762.0 328815.0 343566.0 201727.0 269799.0 True False 87608.41479417428 273099.18805660575 161824.56799874242 230058.18979717168 261550.70364455727 208448.82688801558 345839.4317958482 359529.33060934633 179006.3809805164 316433.39766543073 0.2768620993881431 0.8630542479759269 0.5114016699648174 0.7270351091082216 0.8265584656177738 0.6587447103431583 1.092929615986707 1.1361927447035205 0.5657000250326998 1.0 18.271542350175167 -4.56366646896569 0.3605823954032638 0.9615923030990278 8.699535392151836e-17 0.3833021944611579 0.20311634766799305 8.312718215587036 0.7659184735219359 0.18472284381349702 3.598461032359561 2.7310743979362638e-05 4.56366646896569 -0.9615923030990277 YNLDAS(ph)EEEDSNKK ddPTM_PC-9_AZD4547_30min_R2 2 YNLDASEEEDSNKK 14 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 YNLDAS(0.999)EEEDS(0.001)NKK;YNLDAS(0.889)EEEDS(0.111)NKK 138.81 2.8464e-05 22453000.0 124689.0 141028.0 114064.0 95934.0 105114.0 141425.0 149573.0 130372.0 154226.0 119511.0 True False 164337.5083076834 186612.54304714865 112551.43683190648 73817.89846552501 90520.73549971232 132581.67239311518 162884.70723870458 110226.00305052311 162378.0715013808 115326.95626631715 1.4249704806930767 1.618117299620882 0.9759334718935845 0.6400749734091834 0.7849052678601747 1.1496156378822036 1.412373243099951 0.9557696363371045 1.4079802047876084 1.0 16.815370239173156 -6.994283239364387 24.98261551001819 1.20329487121112 1.0750325844468942 0.025753222638251416 0.29812540219804645 694.8885943549823 3036685.2695759414 0.11795835761669544 0.1037283760462728 1.0132503458156941e-07 6.994283239364387 -0.1282622867642258 YNLDAS(ph)EEEDSNKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YNLDASEEEDSNKK 14 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 YNLDAS(0.993)EEEDS(0.007)NKK;YNLDAS(1)EEEDSNKK 161.26 3.2371e-13 4499800.0 31102.0 50865.0 30649.0 35083.0 37740.0 22621.3 34217.0 23055.3 22749.5 22282.0 True False 36366.954307499036 55914.54104492594 31379.788396979773 33117.41325062064 30345.11791885684 21434.999205477303 30975.7180503727 22450.122804109575 23082.168399674385 26321.550215785064 1.3816418109633122 2.124287535746809 1.1921709830814327 1.2581862762308007 1.1528621099474163 0.8143517015431222 1.1768196704385794 0.8529179558218501 0.8769304319253955 1.0 14.68395683909239 -5.684659696400775 1.3479653054850371 0.9689239521237542 1.7533862457263936 0.6043063851484147 0.22716926124108267 0.2910978962654786 1.034395011258215 0.07218310295447573 0.19707482985821095 2.0669991764828916e-06 5.684659696400775 0.7844622936026394 YNLDAS(ph)EEEDSNKK ddPTM_PC-9_Lapatinib_30min_R1 4 YNLDASEEEDSNKK 14 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 Y(0.226)NLDAS(0.771)EEEDS(0.003)NKK;YNLDAS(0.999)EEEDSNKK;YNLDAS(1)EEEDSNKK;YNLDAS(0.989)EEEDS(0.011)NKK 137.27 0.00010074 129785000.0 82365.0 142106.0 111509.0 131188.0 153085.0 136084.0 159920.0 170822.0 129677.0 145837.0 True False 81190.459996109 141776.96228796666 102341.16045718764 140836.00315033874 144080.84127668996 130264.00454729804 168199.87510543055 178759.01373637078 115071.41070065206 171044.7311344121 0.4746738438397561 0.8288882174134556 0.5983298040134593 0.8233869714447127 0.8423576705409702 0.7615785863928931 0.9833677657878512 1.0451009659917354 0.6727562429866693 1.0 17.384014138417925 -3.915555967571897 0.3269072008150856 0.9454169228604874 4.82605601515304e-15 0.46256989930334824 0.12717822569694945 11.590964152760684 0.6436710868549393 0.12215197536743855 4.832499212283279 0.00012146300808887745 3.915555967571897 -0.9454169228604826 YNLINEGS(ph)PPSK ddPTM_PC-9_AZD4547_30min_R2 2 YNLINEGSPPSK 12 0 Q68D06 Q68D06 SLFN13 Schlafen family member 13 1 YNLINEGS(0.5)PPS(0.5)K;Y(0.182)NLINEGS(0.789)PPS(0.03)K 127.3 0.00023828 49549000.0 132627.0 102365.0 196216.0 285460.0 231400.0 197454.0 132084.0 165885.0 110439.0 155732.0 True False 174799.62718702623 135452.4843933216 193614.04763474298 219651.60731303546 199274.10425474728 185107.17016588335 143839.22011938668 140251.2849080789 116276.58007431292 150279.87008113187 1.1631606221954864 0.9013348515685741 1.2883565013079676 1.461616963033384 1.3260199396443768 1.2317496020321896 0.9571422975128467 0.9332672754665091 0.7737335679857753 1.0 17.197292248301373 -7.3256871167145015 3.568026838887546 0.898662346811126 1.2329895944638025 0.5338255029797636 0.1436529689327031 0.2189656701805575 5.547333649449378 0.07209028210257698 0.04759206406352207 4.724032570825811e-08 7.3256871167145015 0.3343272476526765 YNLINEGS(ph)PPSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YNLINEGSPPSK 12 0 Q68D06 Q68D06 SLFN13 Schlafen family member 13 1 YNLINEGS(0.967)PPS(0.033)K;YNLINEGS(0.993)PPS(0.007)K;Y(0.01)NLINEGS(0.92)PPS(0.071)K;YNLINEGS(0.991)PPS(0.009)K 133.98 5.5997e-05 41973700.0 232370.0 213676.0 210611.0 231245.0 266259.0 250907.0 249746.0 228770.0 223690.0 189286.0 True False 271705.6514832988 234888.34114451183 215632.764986665 218289.09235640554 214087.4603062247 237748.99522347053 226088.25087554066 222765.02990185103 226961.0430700964 223602.053412848 1.2151303949862868 1.050474884105046 0.9643595024976407 0.9762392116917062 0.957448543242776 1.0632683895102801 1.0111188489763208 0.9962566376371708 1.015022177149002 1.0 17.77057391143245 -4.792666785793212 3.083573407755878 0.9985707464123147 1.2458889413381855 0.8397256828972092 0.02848473616141562 0.1365067652484306 1.953778112224506 0.007717258000687958 0.08248557594998944 1.611881883787395e-05 4.792666785793212 0.24731819492587082 YNLINEGS(ph)PPSK ddPTM_PC-9_Lapatinib_30min_R1 2 YNLINEGSPPSK 12 0 Q68D06 Q68D06 SLFN13 Schlafen family member 13 1 YNLINEGS(0.997)PPS(0.003)K;YNLINEGS(0.957)PPS(0.043)K 145.81 8.6755e-05 52129000.0 160603.0 135620.0 159118.0 119807.0 125578.0 150481.0 118811.0 114447.0 147215.0 88929.0 True False 158312.77176901672 135305.98022246826 146035.93225324256 128618.00644443618 118191.74893584714 144045.27841834404 124962.45223331223 119764.6254293147 130634.09645732475 104300.25915955602 1.5178559770099291 1.2972736723068006 1.400149275083203 1.2331513601292154 1.133187490503166 1.381063475575713 1.1981029888156622 1.1482677645709554 1.2524810341792523 1.0 16.670383217028352 -1.522878745280339 0.09762742615010717 0.8900949007934353 2.440206255437054 0.6208498398544814 0.08768861492371638 94.14768995707631 0.6562071310681515 1.226563530235796 19.534003331012503 0.029999999999999905 1.522878745280339 1.5501113546436187 YNPPS(ph)WEHR ddPTM_PC-9_AZD4547_30min_R2 1 YNPPSWEHR 9 0 O95248;O95248-5;O95248-4 O95248 SBF1 Myotubularin-related protein 5 1 YNPPS(1)WEHR 60.161 0.04034 2457000.0 15708.0 21977.0 31605.0 32171.0 37727.0 32815.0 31579.0 35544.0 23829.0 27488.0 True False 20702.817253302972 29080.63546634136 31185.897049659856 24754.472986995286 32489.25726542283 30763.0728625071 34389.46982337092 30051.491519864696 25088.55229213232 26525.65348669602 0.780482835745649 1.0963211700298654 1.1756881716524414 0.933227639402397 1.2248240097729493 1.1597479729551756 1.2964607956075054 1.1329218160426118 0.9458222133797956 1.0 14.695100673400228 -4.763372450079534 5.015113176071539 1.1207798516546117 0.7594012370500989 0.4284417198296161 0.11258570031171802 0.16101030028954808 10.731229068511073 0.028273056864066486 0.20518147336053175 1.7243584513372966e-05 4.763372450079534 -0.3613786146045128 YNPPS(ph)WEHR ddPTM_PC-9_Lapatinib_30min_R1 1 YNPPSWEHR 9 0 O95248;O95248-5;O95248-4 O95248 SBF1 Myotubularin-related protein 5 1 YNPPS(1)WEHR 60.157 0.04035 2650000.0 16419.0 25747.0 27171.0 23857.0 25403.0 24737.0 22693.0 20700.0 28484.0 20261.0 True False 16184.862049124158 25687.38440339095 24937.105263093086 25611.52336461899 23908.84548421959 23679.056174763442 23867.932502298238 21661.79756906526 25275.831970182626 23763.086853914512 0.6810925764241784 1.0809784335387997 1.0494051305874506 1.077786043625893 1.0061338255926573 0.996463814669043 1.0044121224245095 0.9115733870028293 1.063659453233826 1.0 14.536434635703767 -4.755029115805897 24.999833870961965 1.0192815981632641 0.681092012756355 0.8190070269749256 0.047951618809517225 92.3294802844757 360048.56045468786 0.012538859139708114 0.11576351908432266 1.7578057638611464e-05 4.755029115805897 -0.33818958540690913 YNPTWHCIVGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YNPTWHCIVGR 11 0 P63167;Q96FJ2 P63167 DYNLL1;DYNLL2 Dynein light chain 1, cytoplasmic;Dynein light chain 2, cytoplasmic 0 ; 120.86 0.00069263 7797300.0 35528.0 31169.0 33408.0 47863.0 44207.0 42384.0 43625.0 43347.0 38354.0 32251.0 False True 41542.188690014336 34263.25233125519 34204.57342054555 45181.39128393965 35544.95569260476 40161.30842723226 39492.52418235116 42209.187179942914 38914.85469136071 38097.85100122446 1.0904076633792068 0.899348688464186 0.8978084726995814 1.185930179696685 0.9329910942079739 1.0541620425241698 1.0366076601297505 1.107915172921074 1.0214448759881494 1.0 15.217422000960541 -5.7152972502589545 24.999999811594108 1.0478689356049902 0.9562044069234 0.19453827816668112 0.07979523863382085 190.58762451677097 103259.72186117126 0.02076730960500678 0.03596986833568699 1.926206081684687e-06 5.7152972502589545 -0.09166452868159014 YNPTWHCIVGR ddPTM_PC-9_Lapatinib_30min_R1 1 YNPTWHCIVGR 11 0 P63167;Q96FJ2 P63167 DYNLL1;DYNLL2 Dynein light chain 1, cytoplasmic;Dynein light chain 2, cytoplasmic 0 71.176 0.025499 3169500.0 20413.0 17991.0 19432.0 23268.0 15075.0 19959.0 15998.0 16333.0 24007.0 18832.0 False True 20121.906876714256 17949.34294486374 17834.37596968918 24979.206339772594 14188.318138590334 19105.400096701436 16826.298161184823 17091.890806547963 21303.078855082662 22087.08610793732 0.9110258717868244 0.8126623338699883 0.8074571667142699 1.1309416831945047 0.64238071374619 0.8650031970417151 0.7618161163929199 0.7738409097072221 0.9645038168899557 1.0 14.430915479776438 -8.405143273922834 5.347430519409981 0.9980703113983395 0.8382074337853038 0.19204754927829337 0.11907712507640725 0.35311643714545443 13.01353031548442 0.1119042716055626 0.029099303600769205 3.9342026454239855e-09 8.405143273922834 -0.15986287761303564 YNSNLAT(ph)PIAIK ddPTM_PC-9_Lapatinib_30min_R1 2 YNSNLATPIAIK 12 0 Q8IX90 Q8IX90 SKA3 Spindle and kinetochore-associated protein 3 1 YNS(0.007)NLAT(0.993)PIAIK;Y(0.004)NS(0.025)NLAT(0.971)PIAIK 91.20700000000001 0.015966 6699800.0 58993.0 53080.0 59269.0 53633.0 47899.0 40377.0 34463.0 28599.0 38210.0 30748.0 True False 58151.74900200875 52957.0965212255 54396.13160495616 57577.34973444315 45081.674993057255 38650.16983338415 36247.325511245945 29927.813945782473 33906.38743086219 36062.75083086537 1.6125156196414683 1.4684707988471197 1.5083744404323038 1.5965878477901325 1.250089745080477 1.07174768820753 1.0051181531116755 0.8298816162456434 0.9402052436289027 1.0 15.138221827863884 -6.642153355318938 1.6033035059052316 0.9294490497417672 1.5457479071959348 0.9449018541831609 0.06589315291669487 0.07876476166226593 0.41803773256202986 0.027528809625422666 0.027525154747914102 2.279536994189868e-07 6.642153355318938 0.6162988574541676 YNTEGRVS(ph)PSPSQESLSSSK ddPTM_PC-9_AZD4547_30min_R2 4 YNTEGRVSPSPSQESLSSSK 20 1 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83;Q5JSH3-3 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 YNT(0.002)EGRVS(0.996)PS(0.002)PSQESLSSSK;Y(0.001)NT(0.001)EGRVS(0.954)PS(0.039)PS(0.005)QESLSSSK;Y(0.012)NT(0.023)EGRVS(0.927)PS(0.035)PS(0.004)QESLSSSK;YNT(0.001)EGRVS(0.957)PS(0.033)PS(0.008)QES(0.001)LSSSK 91.73299999999999 0.00030513 235740000.0 205505.0 163064.0 221143.0 278499.0 256020.0 245753.0 219992.0 256544.0 203481.0 212756.0 True False 270851.3152304573 215771.24910968234 218210.49932773047 214295.35831665763 220476.04222688088 230386.02606063383 239570.86181902606 216901.01959464775 214236.5902453054 205307.4771978863 1.3192472038872523 1.0509663459636713 1.0628473073944966 1.0437776609086105 1.0738821850817168 1.1221511715258938 1.1668881479076132 1.0564691678792923 1.0434914167242566 1.0 17.647426645087776 -4.758071313342229 24.999984028245386 1.0746073608952298 1.3192475437570468 0.7441477656612376 0.0439178949705789 51.39255473514857 381408.216038475 0.011489129965408016 0.08090090651603091 1.7455355036615075e-05 4.758071313342229 0.244640182861817 YNTEGRVS(ph)PSPSQESLSSSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YNTEGRVSPSPSQESLSSSK 20 1 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83;Q5JSH3-3 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 YNT(0.006)EGRVS(0.955)PS(0.021)PS(0.013)QES(0.005)LSSSK;Y(0.001)NT(0.002)EGRVS(0.98)PS(0.017)PSQESLSSSK;Y(0.137)NT(0.037)EGRVS(0.803)PS(0.011)PS(0.008)QES(0.003)LSSSK;Y(0.003)NT(0.017)EGRVS(0.977)PS(0.002)PSQESLSSSK 89.557 0.00032578 190577000.0 144434.0 116181.0 141532.0 157501.0 180631.0 139041.0 150507.0 150811.0 127894.0 114531.0 True False 168883.82349846658 127714.68186652014 144906.6596430989 148676.72959513124 145237.65222048305 131749.44519230843 136249.88738368175 146852.37104746254 129764.20779832298 135294.56367310256 1.2482676237200636 0.9439749713455091 1.0710456925174094 1.0989113350804143 1.0734921513284517 0.9737970367430298 1.0070610650172718 1.0854269902690683 0.9591235913355546 1.0 17.045744345388925 -6.674112024889286 7.945172231680425 1.010666918164662 1.0794283205554192 0.22325928201477507 0.07553323213392989 0.45744920237699715 36.334918926736925 0.024074256654874143 0.02403200096485699 2.117814781155628e-07 6.674112024889286 0.06876140239075723 YNTEGRVS(ph)PSPSQESLSSSK ddPTM_PC-9_Lapatinib_30min_R1 3 YNTEGRVSPSPSQESLSSSK 20 1 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83;Q5JSH3-3 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 Y(0.001)NT(0.002)EGRVS(0.847)PS(0.106)PS(0.034)QES(0.007)LS(0.002)S(0.001)S(0.001)K;Y(0.006)NT(0.029)EGRVS(0.961)PS(0.003)PS(0.001)QESLSSSK;YNTEGRVS(0.986)PS(0.011)PS(0.003)QESLSSSK 86.91799999999999 0.00035082 132343000.0 122433.0 154913.0 173594.0 159604.0 160717.0 171444.0 134926.0 140463.0 182185.0 150340.0 True False 120687.08296853783 154554.30846632656 159321.77141221857 171341.8105833364 151263.9420417794 164111.7397754838 141911.80808201164 146989.42376539222 161665.4068068996 176326.0686845422 0.6844539997341753 0.8765255734410627 0.9035633392204455 0.971732721438241 0.8578648816381177 0.9307287402243932 0.804826020002183 0.8336227584610022 0.9168548247742574 1.0 17.42788625812291 -4.761006072513188 4.425144177721299 0.8946651451098435 0.6658720649583388 0.5656048399672842 0.05662192462594415 0.16191631679168855 6.808704941207556 0.014159963724928604 0.11918055020998959 1.7337797550467726e-05 4.761006072513188 -0.22879308015150468 YNVST(ph)TPYLQSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YNVSTTPYLQSVK 13 0 Q8WWK9-6;Q8WWK9-5;Q8WWK9 Q8WWK9-6 CKAP2 Cytoskeleton-associated protein 2 1 YNVST(0.5)T(0.5)PYLQSVK 227.92 2.9351e-19 11086000.0 56505.0 49260.0 46331.0 48843.0 61942.0 39822.0 40084.0 37378.0 37058.0 24717.0 True False 66070.18047537887 54150.20725200139 47435.70675129599 46106.48506114256 49804.90975436754 37733.664217375495 36286.95333697107 36396.867105264646 37599.90314315186 29197.996440335657 2.2628326779335457 1.854586405017689 1.6246219787110392 1.5790975642920697 1.705764635465343 1.292337448375335 1.2427891554518566 1.2465535838953692 1.2877562753315965 1.0 14.833581754656002 -1.5228787452816017 0.2279210338670223 1.0359543888505045 7.5078763613338815 0.9088260577058741 0.10630221534631801 14.715238096514662 0.19171527752129794 0.16569956008105577 35.4244454336272 0.029999999999912676 1.5228787452816017 6.471921972483377 up YNVSTT(ph)PYLQSVK ddPTM_PC-9_AZD4547_30min_R2 2 YNVSTTPYLQSVK 13 0 Q8WWK9-6;Q8WWK9-5;Q8WWK9 Q8WWK9-6 CKAP2 Cytoskeleton-associated protein 2 1 YNVSTT(0.955)PYLQS(0.045)VK;YNVS(0.001)T(0.03)T(0.97)PYLQSVK 180.95 0.00021914 30550000.0 99977.0 100736.0 115497.0 153918.0 141186.0 134769.0 101715.0 152624.0 107936.0 125235.0 True False 131767.6063492149 133296.942000153 113965.43431560093 118434.58310939465 121584.76094775576 126341.87312531495 110767.43795193535 129039.46775061438 113641.27660428878 120850.56076856748 1.0903350841834645 1.1029898508739295 0.9430277657862773 0.980008552349215 1.0060752732508564 1.0454388653376918 0.9165653617781583 1.0677606039224667 0.9403454636997118 1.0 16.88286464192305 -5.247466703213784 24.728660722726715 0.989768368705161 1.0966624916883625 0.49150903030623283 0.04440034936358807 545.4247426503163 965280.8691295653 0.010642125868970804 0.027838613823418203 5.656311216202712e-06 5.247466703213784 0.10689412298320145 YNVSTT(ph)PYLQSVK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YNVSTTPYLQSVK 13 0 Q8WWK9-6;Q8WWK9-5;Q8WWK9 Q8WWK9-6 CKAP2 Cytoskeleton-associated protein 2 1 YNVS(0.01)T(0.037)T(0.952)PY(0.001)LQSVK 86.756 0.018185 10178000.0 35595.0 32873.0 34317.0 32250.0 35953.0 25117.0 29290.0 25018.0 21449.0 22995.0 True False 41620.53046670403 36136.41418991154 35135.24742794722 30443.1370559107 28908.267740770014 23799.820304048546 26515.439158763682 24361.30400876212 21762.65104747866 27163.81147168014 1.5322050997922685 1.3303145704565746 1.2934579326092648 1.1207240592009502 1.0642198636560474 0.8761590886780101 0.9761310258837416 0.8968293729383375 0.8011633812938032 1.0 14.729398304106093 -5.561512413353637 0.665394914369477 0.8864592809371261 1.6077428696583569 0.9158015437104067 0.06382598933135913 0.3602999232315687 0.2324213631361649 0.03272910823432128 0.17178140851683665 2.744653892455748e-06 5.561512413353637 0.7212835887212308 YNVSTT(ph)PYLQSVK ddPTM_PC-9_Lapatinib_30min_R1 2 YNVSTTPYLQSVK 13 0 Q8WWK9-6;Q8WWK9-5;Q8WWK9 Q8WWK9-6 CKAP2 Cytoskeleton-associated protein 2 1 YNVS(0.008)T(0.226)T(0.765)PYLQSVK;YNVST(0.001)T(0.981)PYLQS(0.018)VK 180.27 0.00024173 22343000.0 118326.0 118918.0 148651.0 98294.0 98921.0 97421.0 101455.0 87510.0 94745.0 68793.0 True False 116638.64954166915 118642.65267730027 136429.4885894541 105522.8686591716 93102.66126616875 93254.53092944287 106707.84347687237 91576.03407096124 84073.82039091963 80683.77838908945 1.4456270128945985 1.4704647581718093 1.6909159599781822 1.3078573012569903 1.1539204425602192 1.1558027250500371 1.3225439562619945 1.1349993257547382 1.0420164011839164 1.0 16.29999102591436 -5.9814224244962535 4.606166991732812 1.15651743748178 1.5291279200861814 0.7548336871928748 0.10170985081971148 0.09989898471729693 5.372669508921183 0.030203937852232545 0.044017969291448036 1.0437045469672623e-06 5.9814224244962535 0.37261048260440144 YNVTTSKQLY(ph)T(ph)VAVS(ph)CLLLAS(ph)K ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YNVTTSKQLYTVAVSCLLLASK 22 1 E5RFJ6;E7EN43;B4DZA8 E5RFJ6 CCNJL 4 Y(0.274)NVT(0.345)T(0.369)S(0.386)KQLY(0.444)T(0.18)VAVS(1)CLLLAS(1)K 60.138999999999996 0.0062485 35987000.0 22229.0 25887.0 28011.0 33735.0 34517.0 30424.0 34166.0 37664.0 31797.0 23848.0 True False 25991.93065723736 28456.890278777115 28678.88847230905 31844.937320345678 27753.641632357743 28828.511881608985 30929.549139580715 36675.359908306695 32261.970970985996 28171.453619335876 0.9226336350424399 1.0101321239329064 1.0180123773458707 1.1303973785182477 0.9851689588821444 1.0233235484100873 1.0979039121485652 1.3018625309108665 1.1452007910888395 1.0 14.781946386829967 -7.481108923024464 4.77226405674389 1.1736072722368702 1.02056939848996 0.32991487617931936 0.0841567144050311 0.20095602194965 10.661363830462324 0.03692062571719972 0.023317877460827356 3.302866932482859e-08 7.481108923024464 -0.15303787374691025 YPDLSLVKEEPPEPVPS(ph)PIIPILPSTAGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YPDLSLVKEEPPEPVPSPIIPILPSTAGK 29 1 Q8NEZ4;Q8NEZ4-3;H0Y765;H7BY37;Q8NEZ4-2;H7C2V8 Q8NEZ4 KMT2C Histone-lysine N-methyltransferase 2C 1 YPDLS(0.001)LVKEEPPEPVPS(0.889)PIIPILPS(0.051)T(0.059)AGK 51.586000000000006 0.0046426 941330.0 2096.0 1126.3 951.56 3056.8 4802.6 2504.9 2801.9 4815.1 2644.4 3791.6 True False 2450.8114021129823 1238.1116205426142 974.2487992113959 2885.537406279313 3861.5650057525672 2373.538634375569 2536.483748000681 4688.708727020165 2683.069347286707 4478.987065710916 0.5471798346718341 0.2764267014792324 0.2175154303681296 0.644238834349327 0.8621514081420215 0.5299275482499826 0.566307450945515 1.0468234576774695 0.5990348504971277 1.0 12.128956784688771 -6.368529755919629 0.2995471796904025 0.9781245226986859 0.1702279095858729 0.460628047502307 0.19176293704249017 2.8044269769524446 0.4348081796936615 0.2652086067937714 0.7928683550627696 4.2802609214398423e-07 6.368529755919629 -0.807896613112813 YPDVAS(ph)PTLR ddPTM_PC-9_AZD4547_30min_R2 1 YPDVASPTLR 10 0 Q8IVL1-4;Q8IVL1-11;A0A0A0MTL4;A0A0A0MTE8;Q8IVL1-8;Q8IVL1-9;Q8IVL1-10;Q8IVL1-13;Q8IVL1-12;Q8IVL1-3;Q8IVL1-2;Q8IVL1;Q8IVL1-5;E9PNV5 Q8IVL1-4 NAV2 Neuron navigator 2 1 YPDVAS(0.938)PT(0.062)LR 86.463 0.01125 2732500.0 14190.0 12578.0 20109.0 32713.0 24169.0 15327.0 23265.0 27004.0 18565.0 23151.0 True False 18702.124829664448 16643.592523804036 19842.34152101282 25171.5232608118 20813.551537307605 14368.600267062206 25335.539929723054 22831.152290187543 19546.307998801334 22340.49053661598 0.8371402946149161 0.7449967357039565 0.8881784170536138 1.1267220484508058 0.9316515008116887 0.6431640452796739 1.1340637256016468 1.0219628907775042 0.8749274312828991 1.0 14.447373243390984 -5.518646966512532 24.908079504228876 0.9593545186726935 0.7974482486402481 0.20819533500123988 0.13278007602505276 262.601059370966 1545656.6557547266 0.03698772110896031 0.06613596976413015 3.029374975032512e-06 5.518646966512532 -0.1619062700324454 YPDVAS(ph)PTLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YPDVASPTLR 10 0 Q8IVL1-4;Q8IVL1-11;A0A0A0MTL4;A0A0A0MTE8;Q8IVL1-8;Q8IVL1-9;Q8IVL1-10;Q8IVL1-13;Q8IVL1-12;Q8IVL1-3;Q8IVL1-2;Q8IVL1;Q8IVL1-5;E9PNV5 Q8IVL1-4 NAV2 Neuron navigator 2 1 Y(0.067)PDVAS(0.612)PT(0.321)LR 66.663 0.045614999999999996 2226100.0 12588.0 19394.0 13094.0 16528.0 22155.0 17110.0 16136.0 14833.0 14855.0 11242.0 True False 14718.899775667094 21319.3081495192 13406.210619271538 15601.989744498986 17813.886790998222 16212.721479566439 14607.48126547664 14443.649466862598 15072.226272101048 13280.085608376958 1.1083437418793856 1.6053592407620605 1.0094973040546533 1.17484105182706 1.3413984906664596 1.2208295908378484 1.0999538479076048 1.0876171956114256 1.1349494812438277 1.0 13.696976826413716 -7.5843866497317425 0.33397501257988105 0.9858903989360545 1.3117308914570875 0.2120854017228112 0.15173840648242867 2.1509266424168736 0.7143562097819576 0.21506845015419293 0.24513099919548093 2.603834339911158e-08 7.5843866497317425 0.3258404925210331 YPDVAS(ph)PTLRR ddPTM_PC-9_AZD4547_30min_R2 1 YPDVASPTLRR 11 1 Q8IVL1-4;Q8IVL1-11;A0A0A0MTL4;A0A0A0MTE8;Q8IVL1-8;Q8IVL1-9;Q8IVL1-10;Q8IVL1-13;Q8IVL1-12;Q8IVL1-3;Q8IVL1-2;Q8IVL1;Q8IVL1-5;E9PNV5 Q8IVL1-4 NAV2 Neuron navigator 2 1 YPDVAS(0.542)PT(0.458)LRR 53.869 0.042118 2492000.0 10124.0 10183.0 15494.0 21705.0 20706.0 20993.0 12295.0 18019.0 15577.0 16382.0 True False 13343.221407718316 13474.455610581692 15288.539436400244 16701.24758890716 17831.329311576454 19680.30439136405 13389.231181428971 15234.577585427707 16400.368418924227 15808.471166292717 0.8440551440653618 0.8523566554185403 0.9671105621522031 1.0564745580532828 1.1279603906035476 1.2449214212014992 0.8469655946223238 0.9636970852634579 1.0374417770324034 1.0 13.94841023127749 -5.414057443841349 2.6933027299286225 1.041854030108091 0.843846386840481 0.3769851787975794 0.09748567816651436 0.31759679047071504 4.4043880299379135 0.029502652895064107 0.07456502951197383 3.854273740724615e-06 5.414057443841349 -0.19800764326761 YPDVASPT(ph)LR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YPDVASPTLR 10 0 Q8IVL1-4;Q8IVL1-11;A0A0A0MTL4;A0A0A0MTE8;Q8IVL1-8;Q8IVL1-9;Q8IVL1-10;Q8IVL1-13;Q8IVL1-12;Q8IVL1-3;Q8IVL1-2;Q8IVL1;Q8IVL1-5;E9PNV5 Q8IVL1-4 NAV2 Neuron navigator 2 1 YPDVAS(0.348)PT(0.652)LR 81.625 0.039191000000000004 1768600.0 10692.0 16134.0 16651.0 16845.0 14094.0 10360.0 13824.0 14818.0 11977.0 10793.0 True False 12501.944423374054 17735.676894108616 17048.02298926916 15901.229262226843 11332.381874625551 9816.703362262326 12514.490642907096 14429.043200968796 12152.140966742123 12749.685462659008 0.9805688508935744 1.3910677989706073 1.337132828821466 1.2471860038271536 0.88883619190572 0.7699565131244426 0.9815528923877577 1.131717581835901 0.9531326088265503 1.0 13.638174035491668 -6.252374696447326 23.73543786527392 0.9529407170915487 1.2568619844580746 0.5271124381957801 0.13170921914003486 264.43979743306255 692421.1059106353 0.04092820656675163 0.051989469941566446 5.592748674494126e-07 6.252374696447326 0.3039212673665259 YPDVASPT(ph)LR ddPTM_PC-9_Lapatinib_30min_R1 1 YPDVASPTLR 10 0 Q8IVL1-4;Q8IVL1-11;A0A0A0MTL4;A0A0A0MTE8;Q8IVL1-8;Q8IVL1-9;Q8IVL1-10;Q8IVL1-13;Q8IVL1-12;Q8IVL1-3;Q8IVL1-2;Q8IVL1;Q8IVL1-5;E9PNV5 Q8IVL1-4 NAV2 Neuron navigator 2 1 YPDVAS(0.077)PT(0.923)LR 156.01 0.0007501000000000001 3404200.0 21407.0 22628.0 21649.0 24236.0 20801.0 19042.0 20391.0 21849.0 24083.0 19246.0 True False 21101.732254436985 22575.606256260184 19869.102787556658 26018.396288925916 19577.52607633946 18227.61804907004 21446.74620607074 22864.184303695994 21370.51893476719 22572.645456316997 0.9348364725469794 1.0001311676094375 0.8802292503112988 1.1526516171654404 0.8673119911543489 0.807509163440522 0.9501210767508347 1.0129155817355653 0.9467441012230408 1.0 14.462287888156894 -7.571308959543926 12.104574536963575 0.9842507101892961 0.9410905856668978 0.05197527772418309 0.08817644393379002 3.311240740203729 818.3000286776308 0.04301684678721121 0.024829656297959527 2.683434755836628e-08 7.571308959543926 -0.04316012452239826 YPEGSSEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YPEGSSEER 9 0 P21980;P21980-2;P49221 P21980 TGM2;TGM4 Protein-glutamine gamma-glutamyltransferase 2;Protein-glutamine gamma-glutamyltransferase 4 0 107.29 0.011574 3582700.0 8284.5 5525.3 8376.1 7575.2 8360.5 7666.8 7678.6 5384.3 7504.4 9757.1 False True 9686.902223666504 6073.8152685644245 8575.817990536147 7150.786103129762 6722.320041351416 7264.739511369957 6951.227419750178 5242.967830137415 7614.137653070018 11525.984992838896 0.8404402946633182 0.5269671331637245 0.7440420923560381 0.6204056406088114 0.5832317190702573 0.6302922930997694 0.6030918332853098 0.4548824099107257 0.6606062438742275 1.0 13.492602425957827 -8.564329277571833 22.19394825268306 1.0000000016635187 0.619799366568572 0.5505035425381709 0.10082703199237783 4149.799395462833 2221931.9665168356 0.09353714933799828 0.02415118813020547 2.726909484337396e-09 8.564329277571833 -0.3802006350949466 YPEGSSEER ddPTM_PC-9_Lapatinib_30min_R1 1 YPEGSSEER 9 0 P21980;P21980-2;P49221 P21980 TGM2;TGM4 Protein-glutamine gamma-glutamyltransferase 2;Protein-glutamine gamma-glutamyltransferase 4 0 104.06 0.012572 4195700.0 4885.4 4358.4 5547.0 4768.6 6672.0 6790.4 3684.3 4319.6 6295.2 5484.4 False True 4815.7333001273655 4348.308392579297 5090.947072039209 5119.298751583271 6279.566077656694 6499.9904211955245 3875.0550265816473 4520.304385475089 5586.168284605168 6432.371232496361 0.7486715436755679 0.6760039549041618 0.7914572850397266 0.795864941022147 0.976244350750825 1.0105123268317524 0.6024302526267229 0.7027430821527364 0.8684461892348233 1.0 12.651134956077303 -12.732797131673502 1.0580838756636834 4.884763372083981 0.7962277528603763 0.2020829467155003 0.1210637122737593 114431.5365263652 1931.6456087889944 1062174.0153761364 0.039661068021478396 1.8501326540544267e-13 12.732797131673502 -4.088535619223604 YPEGYRT(ph)LPR ddPTM_PC-9_Lapatinib_30min_R1 1 YPEGYRTLPR 10 1 Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;B4DJX4;Q9HAU0-8;A0JP02;Q9HAU0-5;Q9HAU0-3 Q9HAU0 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 YPEGY(0.085)RT(0.915)LPR 91.087 0.005979600000000001 23348000.0 38148.0 25977.0 35723.0 25396.0 28194.0 29814.0 24789.0 22451.0 24049.0 14680.0 True False 37604.00252451359 25916.851852522126 32785.99283476775 27263.70655857249 26535.68435153672 28538.924719828497 26072.45312649146 23494.15542140505 21340.34837280305 17217.418440129553 2.184067411457454 1.50526932609806 1.9042339563724426 1.5834956125029473 1.5412115610600827 1.6575611970556112 1.5143067595849913 1.364557381415902 1.2394627247406595 1.0 14.071581222468568 -1.5228787456474002 0.0766126976614643 0.3948555462023982 4.494633113235063 0.7494681390625424 0.15644199019530014 103.94033005609607 0.5853961417741942 4.970628902848897 45.34684192587919 0.02999999997464421 1.5228787456474002 4.099777567032665 up YPEPERPSS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 1 YPEPERPSSR 10 1 O15027;O15027-5;F1T0I1;O15027-2;O15027-4;O15027-3;A0A3F2YNX0;A0A3F2YNZ0 O15027 SEC16A Protein transport protein Sec16A 1 YPEPERPS(0.328)S(0.672)R 92.295 0.036312 12831000.0 22349.0 22403.0 26641.0 25076.0 25224.0 21419.0 20230.0 26162.0 29110.0 25084.0 True False 22030.29916169536 22351.127229936206 24450.67981723391 26920.172691083782 23740.37391229206 20502.959300127684 21277.410413849786 27377.58202907659 25831.325258110403 29419.735977670964 0.7488272219171493 0.7597324206750291 0.83109786694862 0.9150378749665088 0.8069540097270269 0.6969117369268389 0.7232359403224743 0.9305855786692195 0.8780270930274799 1.0 14.844496678983322 -7.7775872854566535 24.87818631830682 0.9282298541937622 0.7867355859421202 0.5454351002386015 0.06386066753001665 216.7194084694024 333882.5803360854 0.03844671023679046 0.01855956947375833 1.6688323679172657e-08 7.7775872854566535 -0.14149426825164202 YPESNRT(ph)PVKPSSVEEEDSFFR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YPESNRTPVKPSSVEEEDSFFR 22 2 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 Y(0.072)PES(0.215)NRT(0.688)PVKPS(0.01)S(0.015)VEEEDSFFR;Y(0.015)PES(0.183)NRT(0.759)PVKPS(0.034)S(0.009)VEEEDSFFR 55.843999999999994 0.005971 43856400.0 41362.0 55605.0 60034.0 63967.0 64682.0 57074.0 57614.0 49624.0 51931.0 39633.0 True False 48363.769663262035 61125.09691935727 61465.43824021282 60383.136373812085 52008.02642362211 54080.938966965245 52156.38483076171 48321.42258097414 52690.39263120022 46818.149165344614 1.0330132763783304 1.3055855049606027 1.3128549363012905 1.2897377929349767 1.110851824576592 1.1551276573529448 1.1140206471333243 1.0321087749607638 1.1254266469423426 1.0 15.514780281902885 -6.793788669495992 1.2705314043227616 1.0669820094792297 1.2407618693857436 0.4021304861090629 0.08601582265487506 0.4469699033609607 1.514202803566405 0.043401730973016465 0.037987657308796684 1.6077233913019904e-07 6.793788669495992 0.1737798599065139 YPGGS(ph)PIPADPR ddPTM_PC-9_AZD4547_30min_R2 2 YPGGSPIPADPR 12 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 YPGGS(1)PIPADPR;YPGGS(1)PIPADPR 129.82 0.00016416 13935600.0 29117.0 28277.0 41248.0 45122.0 41337.0 42048.0 40215.0 41769.0 38076.0 43589.0 True False 38375.60032877658 37416.98726312666 40701.024569035595 34719.82002795064 35598.07107855868 39418.73191292697 43794.05709322213 35314.560806134046 40088.61962630535 42062.96237745901 0.9123370813592901 0.8895471252680467 0.967621448147141 0.8254249835374539 0.8463044223826522 0.9371363709288091 1.0411548454488027 0.8395642819740784 0.9530622039066919 1.0 15.360262838196642 -6.957023227300512 12.297303067769851 0.951363863518646 0.8894606893523211 0.23682899997792717 0.05960321613726429 1.5766263086579824 448.0349567975104 0.021365012598943453 0.01883656648407805 1.1040195722254461e-07 6.957023227300512 -0.06190317416632485 YPGGS(ph)PIPADPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YPGGSPIPADPR 12 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 Y(0.001)PGGS(0.999)PIPADPR 68.676 0.033951 3101100.0 7347.5 15596.0 13776.0 12985.0 17380.0 16891.0 17762.0 13407.0 10148.0 8402.7 True False 8591.28663026008 17144.26780962675 14104.47208577093 12257.492547938002 13974.513763373918 16005.20622509392 16079.45477425607 13055.080455890715 10296.395301870172 9926.042994263404 0.8655298627283072 1.7272006397247122 1.4209561749755046 1.234882072848367 1.407863513330565 1.6124457887542771 1.6199259648128597 1.3152351308004295 1.0373111730244176 1.0 13.277002988287274 -8.196650956678745 3.4759934175558387 1.0060423584743865 1.427605539297529 0.3156296503616779 0.2273339823956051 0.27288814227853797 6.1699211852032585 0.1841016777712873 0.05783536977077944 6.358417538063112e-09 8.196650956678745 0.4215631808231426 YPIEHGIITNWDDMEK ddPTM_PC-9_AZD4547_30min_R2 3 YPIEHGIITNWDDMEK 16 0 P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P68133 ACTA1;ACTC1;ACTG2;ACTA2 Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle 0 ;; 98.676 0.0016937 114414800.0 302292.0 238407.0 328575.0 372388.0 382156.0 342325.0 314653.0 350222.0 284094.0 372327.0 False True 398414.5679357951 315467.4004470143 324217.88081290916 286539.6999372478 329100.2358927273 320919.3636342446 342656.5074363696 296103.2372009361 299110.62885060365 359291.9450575183 1.1088881156854595 0.8780252515722605 0.9023800429508816 0.7975121732589252 0.9159688671563241 0.8931994386427707 0.9536993861120778 0.8241299068186279 0.8325002354358922 1.0 18.45479706645422 -4.7605598248090875 24.995764993535328 0.8837229779029534 1.1088883791808604 0.5644510389909907 0.05790906956398497 15.254814544218117 433276.5105523786 0.013896879950029072 0.08168292605120091 1.7355621697411497e-05 4.7605598248090875 0.22516540127790696 YPIEHGIITNWDDMEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 YPIEHGIITNWDDMEK 16 0 P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P68133 ACTA1;ACTC1;ACTG2;ACTA2 Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle 0 ;;;; 131.96 6.9852e-06 174591000.0 272188.0 236691.0 260403.0 310671.0 315623.0 274289.0 314048.0 267538.0 246207.0 227408.0 False True 318264.05244194996 260188.11824367588 266611.99510387675 293265.1110789718 253778.93886866278 259904.80198181214 284299.0999293759 260515.41097994306 249807.31159711757 268635.27023926313 1.1847441036260218 0.9685553129785835 0.9924683190945689 1.0916850598872287 0.9446970185360679 0.967500662702723 1.0583089096087852 0.9697736665327378 0.9299125590419448 1.0 18.035289209055968 -4.756868556766465 24.969186635187445 0.9935355619323308 1.184744395106351 0.6024046079345913 0.04708650858508578 96.72808508123286 528334.198211156 0.011834440113016582 0.09195941538967417 1.7503763760295996e-05 4.756868556766465 0.19120883317402015 YPIEHGIITNWDDMEK ddPTM_PC-9_Lapatinib_30min_R1 10 YPIEHGIITNWDDMEK 16 0 P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P68133 ACTA1;ACTC1;ACTG2;ACTA2 Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle 0 ;;;;;;;;; 127.03 2.1865e-05 294233700.0 843624.0 742395.8 844862.0 741036.0 778639.0 717261.0 768306.8 685809.0 733891.6 716506.0 False True 831593.7670583051 740676.8281377626 775400.7076216327 795534.2594636278 732840.984883173 686585.4190470551 808085.9667499552 717674.189808845 651232.9997868454 840353.1074157668 0.989576595504718 0.8813876233711728 0.922708205371104 0.9466666481546492 0.8720631582321241 0.8170201466362463 0.9616028781460227 0.8540150366264713 0.7749516174093782 1.0 19.680636134798306 -6.271431401761014 23.165030981637823 0.8735798202743833 0.9303652173458701 0.13865844412299888 0.06578060532594543 502.63585549399886 1165283.4556371213 0.019793413724896968 0.02274959610625503 5.352646939098209e-07 6.271431401761014 0.056785397071486776 YPIEHGIVTNWDDMEK ddPTM_PC-9_AZD4547_30min_R2 4 YPIEHGIVTNWDDMEK 16 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ;;; 159.22 4.319399999999999e-05 83050000.0 386371.0 360141.0 443301.0 565420.0 526057.0 511952.0 434952.0 493933.0 424569.0 470074.0 False True 509228.9409839528 476549.5353088974 437422.5390922717 435071.1546519186 453023.06595479447 479939.56050910236 473661.8853863264 417607.004301186 447010.85056520795 453616.85233939014 1.1225970515816603 1.050555182972676 0.9642995775760949 0.9591159420294291 0.9986909957565875 1.0580285058501704 1.0441893482209934 0.9206161590944112 0.9854370450742432 1.0 18.79111471333873 -4.938645892524965 3.091906980459223 0.9920858703328512 1.1244374692091483 0.5409300290777175 0.037903679268071234 0.23805276077475035 4.13455524774076 0.010764221185085012 0.06438419856942341 1.1517390911733105e-05 4.938645892524965 0.1323515988762971 YPIEHGIVTNWDDMEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 YPIEHGIVTNWDDMEK 16 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ;;;; 136.81 4.198e-07 61795000.0 342264.0 362474.9 344681.0 425449.0 403856.0 398454.0 422249.0 384330.0 362048.1 332088.6 False True 400202.53517786175 398459.01255884 352899.502249971 401612.47185426863 324723.3159045538 377558.3708018214 382250.51790197333 374241.7447312954 367342.3685347877 392293.63436808944 1.020160665677158 1.015716233072917 0.8995799863498297 1.0237547507014486 0.8277557611344406 0.9624381782538894 0.9743989818180617 0.9539837304118579 0.9363964549832844 1.0 18.581574399859214 -5.1924275318243485 10.342223878185928 0.9456299538258538 1.0181984259505839 0.23211261293916585 0.05133145774130157 0.8911905923564948 129.9783777789431 0.012463102455152595 0.03305932055351718 6.4205534858415125e-06 5.1924275318243485 0.07256847212473005 YPIEHGIVTNWDDMEK ddPTM_PC-9_Lapatinib_30min_R1 5 YPIEHGIVTNWDDMEK 16 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65 P60709;P63261 ACTB;ACTG1 Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed 0 ;;;; 170.42 2.4325e-05 48403300.0 321721.0 291046.0 308752.0 279791.0 290274.0 292940.0 254828.0 269845.0 308077.0 217596.0 False True 317133.1995435936 290372.10086881305 283367.60237718624 300367.7634954147 273200.65402064123 280411.6390764929 268021.74695702 282382.98381760495 273378.1240653685 255207.17867155516 1.242649995953819 1.1377897063096105 1.110343383960499 1.1769565615627922 1.0705053652595062 1.0987607814801137 1.0502124131153727 1.106485269291834 1.0712007612340673 1.0 17.961309385389875 -1.5228787452803376 0.1826701966274965 1.015755950082491 1.8430521685571368 0.7207296702501709 0.034087474956678326 31.995412502495828 0.36418936290350673 0.07501140385049929 7.3766920997207475 0.029999999999999995 1.5228787452803376 0.8272962184746457 YPLSS(ph)LMY(ph)T(ph)ACK ddPTM_PC-9_AZD4547_30min_R2 1 YPLSSLMYTACK 12 0 Q9Y6X4 Q9Y6X4 FAM169A Soluble lamin-associated protein of 75 kDa 3 YPLS(0.002)S(0.998)LMY(1)T(1)ACK 66.29899999999999 0.021064 0.0 670.81 758.69 600.03 913.71 949.39 894.71 1014.2 847.63 0.0 1177.1 True False 884.1136262852151 1003.9217055084188 592.0732101473629 703.0682761787775 817.5835861642795 838.7636422615789 1104.4618352342627 716.648260099677 0.0 1135.8900872813558 0.7783443452713427 0.8838194088929936 0.5212416384092526 0.6189580171982169 0.7197735021361861 0.738419721814 0.9723316081379726 0.6309133851276985 0.0 1.0 10.149607526013668 -8.009504171070454 24.986166315303976 0.4384855594868389 0.7422900830892653 0.12338836369890216 0.25424649562988205 680.4918950604404 1788982.5439570001 0.14232352764477857 0.062200375093949364 9.783535583925458e-09 8.009504171070454 0.3038045236024263 YPLSS(ph)LMY(ph)T(ph)ACK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YPLSSLMYTACK 12 0 Q9Y6X4 Q9Y6X4 FAM169A Soluble lamin-associated protein of 75 kDa 3 YPLS(0.01)S(0.997)LMY(0.993)T(0.999)ACK 62.463 0.027097000000000003 0.0 0.0 1298.5 0.0 908.81 0.0 0.0 1043.0 1233.2 0.0 791.55 True False 0.0 1427.4064985124614 0.0 857.892322101774 0.0 0.0 944.1994893339196 1200.8298066834059 0.0 935.0517490936478 0.0 1.5265534767418558 0.0 0.917481115813467 0.0 0.0 1.0097831379377011 1.2842388753856442 0.0 1.0 9.868902400865709 -10.89257377805662 5.230964292275323 1.000223300941374 0.5574184242210108 0.05444297599772696 0.5792535017290704 0.0014611744925708 0.00017606360651746373 0.5432672330225048 0.13169617713930928 1.28063752102954e-11 10.89257377805662 -0.44280487672036306 YPLSS(ph)LMY(ph)T(ph)ACK ddPTM_PC-9_Lapatinib_30min_R1 1 YPLSSLMYTACK 12 0 Q9Y6X4 Q9Y6X4 FAM169A Soluble lamin-associated protein of 75 kDa 3 YPLS(0.002)S(0.999)LMY(0.999)T(1)ACK 68.016 0.019169 0.0 1087.4 808.94 509.98 957.71 674.97 852.78 998.09 477.36 1043.7 757.13 True False 1071.893476595263 807.0669491311253 468.0514129797287 1028.1431882269048 635.2695916420772 816.3085873272736 1049.7662165081229 499.539888288357 926.1475153517633 887.9989116876905 1.2070887277981805 0.9088602908276661 0.5270855705106343 1.1578203246588024 0.715394561052685 0.9192675538034552 1.1821706115753958 0.5625456086865627 1.0429601919123632 1.0 9.79441409821527 -4.771297721088134 5.602656092186755 0.8773433353356536 1.2200030151973886 0.1613391581146021 0.21541782658506897 0.23611135544767636 24.088177070170428 0.05067846594454343 0.30727313916477966 1.6931766822425346e-05 4.771297721088134 0.34265967986173507 YPPS(ph)PAK ddPTM_PC-9_AZD4547_30min_R2 3 YPPSPAK 7 0 P30838;A8MYB8;I3L3I9 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 1 Y(0.024)PPS(0.976)PAK;Y(0.003)PPS(0.997)PAK;Y(0.002)PPS(0.998)PAK 82.645 0.022177000000000002 109784000.0 462716.0 447721.0 488075.0 631934.0 615002.0 537357.0 480542.0 539020.0 497900.0 592230.0 True False 609850.0629093046 592438.0575886522 481602.80659746024 486251.3795829745 529619.5880072521 503755.98184300493 523309.3070667957 455726.8444473755 524217.97751700436 571496.2079607836 1.0671113026022963 1.0366438995327607 0.8427051656491622 0.850839205596866 0.9267245882471278 0.8814686341323422 0.9156829035385401 0.7974275911182385 0.9172728886295191 1.0 19.124384400218084 -5.196387048864615 5.932915129668343 0.88469468733514 1.056190472416395 0.5936410665169468 0.052896548871477614 0.13592910589451598 9.340016206992694 0.012794696245010654 0.03480721424306639 6.362282533114363e-06 5.196387048864615 0.17149578508125507 YPPS(ph)PAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 YPPSPAK 7 0 P30838;A8MYB8;I3L3I9 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 1 Y(0.004)PPS(0.996)PAK;YPPS(1)PAK;Y(0.024)PPS(0.976)PAK 81.97200000000001 0.037005 134207000.0 480393.0 446410.0 426195.0 576770.0 587670.0 535890.0 495640.0 426538.0 440793.0 402475.0 True False 561714.0467057544 490726.63457909046 436357.10515353875 544455.4468135686 472520.2821243937 507786.98501957086 448689.39107714704 415341.8294543677 447238.76372657303 475440.5315096536 1.1814601605844557 1.0321514512464878 0.9177953418653343 1.1451599321681174 0.9938578030442896 1.068034699118328 0.9437339926666235 0.873593650367889 0.9406828700667731 1.0 18.85890537333225 -7.317950266346205 5.379509069130968 0.927168145616698 1.0502193545629719 0.3638647408684743 0.07490013658817982 0.2348273241565757 14.799596090484215 0.031454785487481596 0.021152427454622664 4.8089441538701896e-08 7.317950266346205 0.12305120894627386 YPPS(ph)PAK ddPTM_PC-9_Lapatinib_30min_R1 3 YPPSPAK 7 0 P30838;A8MYB8;I3L3I9 P30838 ALDH3A1 Aldehyde dehydrogenase, dimeric NADP-preferring 1 Y(0.026)PPS(0.974)PAK;Y(0.011)PPS(0.989)PAK;Y(0.003)PPS(0.997)PAK 82.645 0.022177000000000002 186182000.0 1387290.0 1233930.0 1184744.0 1246488.0 1236699.0 1213904.0 977340.0 995295.0 1225405.0 967374.0 True False 1367506.9902021715 1231072.910897433 1087338.921564095 1338158.8856820695 1163958.7962637823 1161988.1556684333 1027941.8830386524 1041540.0392030337 1087386.984813287 1134583.3069551676 1.2052944740321372 1.085044089183024 0.9583597034246341 1.1794276167108688 1.0258909937494571 1.0241541088655808 0.9060082910943718 0.9179934455391997 0.9584020654520827 1.0 20.11373111233057 -6.84901403941117 1.949077693248031 0.9402361302970516 1.094007451567241 0.5019137720922519 0.06881002895593279 0.2843359090904502 2.2178020660188116 0.02899147763477356 0.024995148567415956 1.415748012417865e-07 6.84901403941117 0.15377132127018955 YPPYT(ph)TPPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YPPYTTPPR 9 0 O43896 O43896 KIF1C Kinesin-like protein KIF1C 1 YPPYT(0.668)T(0.332)PPR 81.97200000000001 0.040231 34131000.0 16186.0 17779.0 26513.0 24491.0 28597.0 30456.0 23347.0 22719.0 21509.0 19586.0 True False 18925.97011192782 19543.98162268236 27145.170471112426 23118.848670893312 22993.623135282174 28858.833745276188 21135.403142357638 22122.650322770267 21823.528433969805 23136.786757309314 0.8180033947863905 0.8447146022343867 1.1732472082596688 0.9992246941373424 0.9938122945278082 1.247313814488919 0.9134977714950239 0.9561677926508674 0.9432393816343305 1.0 14.497900896061156 -5.126472603984908 7.884224359109267 1.0280171001589964 0.8250011598848085 0.3899025992266657 0.09875501444104637 0.26674478024865605 15.607459167357534 0.025598060072430425 0.06861260374446694 7.4735577714434515e-06 5.126472603984908 -0.2030159402741879 YPPYT(ph)TPPR ddPTM_PC-9_Lapatinib_30min_R1 1 YPPYTTPPR 9 0 O43896 O43896 KIF1C Kinesin-like protein KIF1C 1 YPPYT(0.5)T(0.5)PPR 86.13600000000001 0.029087000000000002 3464200.0 22252.0 23853.0 24742.0 17294.0 15661.0 20359.0 17686.0 15755.0 21570.0 16057.0 True False 21934.682399482965 23797.76984402395 22707.808266881944 18565.85845109281 14739.850770710666 19488.293029146997 18601.69454173739 16487.034816455223 19140.559457830343 18832.43105539239 1.1647292022450968 1.263658938881914 1.2057821000427822 0.9858450242820216 0.7826844408645864 1.0348261980530022 0.9877479167200279 0.8754597198822296 1.01636158398943 1.0 14.20093162725381 -5.786121266545415 4.603031476239886 0.944531962623216 1.2197115360050441 0.7185573826707092 0.07379843569720065 0.0950519543534098 4.785106014717298 0.020597619029028253 0.033084249730122375 1.6363595426175985e-06 5.786121266545415 0.2751795733818281 YPS(ph)PPMGSVSAPNLPTAEDNLEYVR ddPTM_PC-9_AZD4547_30min_R2 2 YPSPPMGSVSAPNLPTAEDNLEYVR 25 0 P46109 P46109 CRKL Crk-like protein 1 Y(0.035)PS(0.609)PPMGS(0.322)VS(0.034)APNLPTAEDNLEYVR;Y(0.099)PS(0.773)PPMGS(0.122)VS(0.006)APNLPTAEDNLEYVR 108.88 0.00026553 0.0 5198.3 2662.5 6092.8 9072.3 10841.3 6874.2 7508.2 7475.2 6404.200000000001 6305.6 True False 6851.251268643034 3523.101056974738 6012.005491035201 6980.821400637758 9336.172629459757 6444.355187305994 8176.415254689306 6320.07960300733 6742.712937566578 6084.8428632752675 1.1259536889593948 0.5789962265481364 0.9880297036625757 1.147247604826432 1.5343325767387865 1.0590832552473202 1.3437348241213602 1.038659460074445 1.1081161977512761 1.0 12.571004291512237 -5.642829562260898 3.6265132202827934 1.1951626387936416 0.8396663665240137 0.308128765212604 0.19504800287151453 0.23527015905219442 5.891354805776365 0.05262174392042478 0.09685709168104173 2.2759904620599117e-06 5.642829562260898 -0.3554962722696279 YPS(ph)PPMGSVSAPNLPTAEDNLEYVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YPSPPMGSVSAPNLPTAEDNLEYVR 25 0 P46109 P46109 CRKL Crk-like protein 1 Y(0.022)PS(0.969)PPMGS(0.009)VS(0.001)APNLPTAEDNLEYVR 85.399 7.0747e-06 3090500.0 3227.2 2269.5 2901.0 3361.5 4408.4 2987.2 4437.4 3565.5 3096.2 1145.4 True False 3773.5012198945683 2494.8009613970203 2970.170842103766 3173.166053130042 3544.6056659641895 2830.5459733349453 4017.0573480060752 3471.909402959524 3141.4760675650796 1353.0519530185893 2.7888812484074106 1.843832349401845 2.1951639295723036 2.3451915841449194 2.619711429451291 2.091971388844414 2.9688862567651055 2.565983808096853 2.3217704690175482 1.0 10.40200152007653 -5.863613108556046 6.041121116701085 2.3762664183083326 2.233740471329769 0.0 0.5372445920592348 1.343222222119271 67.97117443103213 0.1434509643311307 0.21566390528163504 1.3689478103509096e-06 5.863613108556046 -0.14252594697856358 YPSS(ph)ISSSPQKDLTQAK ddPTM_PC-9_AZD4547_30min_R2 1 YPSSISSSPQKDLTQAK 17 1 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 Y(0.004)PS(0.215)S(0.257)IS(0.257)S(0.257)S(0.009)PQKDLTQAK 76.301 0.0039694000000000005 180520000.0 42149.0 42015.0 39085.0 39302.0 46135.0 48963.0 45081.0 39156.0 43691.0 41719.0 True False 55551.505246337314 55595.52710189434 38566.707362314686 30241.531109847023 39729.95159806719 45901.33586978319 49093.12166653107 33105.33991536751 46000.4170630557 40258.430508275305 1.379872601713036 1.3809660833764104 0.9579784128541008 0.7511850493930889 0.9868728387188497 1.140167048001237 1.2194494680173822 0.8223206791075116 1.1426281770621958 1.0 15.297003308836405 -5.25766246740831 24.73259318661269 0.9993499988521306 1.3804193993356118 0.5543131211646273 0.13549737749313823 207.11125526458062 1356221.8324973185 0.0368572220401892 0.09011573216428934 5.525066792746372e-06 5.25766246740831 0.38106940048348115 YPSS(ph)ISSSPQKDLTQAK ddPTM_PC-9_Lapatinib_30min_R1 1 YPSSISSSPQKDLTQAK 17 1 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 Y(0.006)PS(0.178)S(0.603)IS(0.115)S(0.044)S(0.054)PQKDLTQAK 75.319 0.0042681 136100000.0 64058.0 82239.0 85465.0 80832.0 81427.0 83140.0 87882.0 85561.0 86089.0 69887.0 True False 63144.52117320153 82048.58064824903 78438.39760444037 86776.65492764718 76637.62395164155 79584.296008806 92432.09995007142 89536.47641578714 76392.75026264052 81966.87483142606 0.7703663376585386 1.0009968150791524 0.9569524001708934 1.0586795593477605 0.9349828709372573 0.9709324184004808 1.1276762733746803 1.0923495204609033 0.9319953996019814 1.0 16.32275337255227 -4.209035111301301 1.582744650978918 1.016322895188331 2.3402466718342262e-11 0.5540428554794242 0.06340615278990391 4.453505278863396 2.9579964196724764 0.018215400422798393 10.995927328601443 6.179664375351584e-05 4.209035111301301 -1.0163228951649286 YPSSIS(ph)SSPQK ddPTM_PC-9_AZD4547_30min_R2 1 YPSSISSSPQK 11 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 YPS(0.083)S(0.083)IS(0.278)S(0.278)S(0.278)PQK 101.39 0.0037519 43033000.0 30878.0 35874.0 34661.0 27972.0 26463.0 35661.0 41692.0 45915.0 38554.0 33791.0 True False 40696.56169770113 47469.56894569454 34201.37249290494 21523.487563091978 22789.06923462995 33431.11203260295 45402.50723189398 38819.8917717361 40591.885730449045 32607.987375179913 1.2480550004345856 1.4557650676050848 1.0488648716460758 0.6600679556038752 0.698879969880515 1.0252430377855695 1.392373798158816 1.1905025393037434 1.244844867713185 1.0 14.99293777759832 -7.131035603159395 9.47728586446518 1.2224909393340195 1.0114029253865666 0.12550842312496024 0.23577052233478799 0.8001480382018626 57.35422215953312 0.10315745772447764 0.07990054882423592 7.395446452177197e-08 7.131035603159395 -0.2110880139474529 YPSSIS(ph)SSPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YPSSISSSPQK 11 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 YPS(0.001)S(0.006)IS(0.478)S(0.311)S(0.204)PQK 112.84 0.0016370999999999998 31213000.0 53747.0 90955.0 57262.0 48475.0 55567.0 27991.0 57886.0 36137.0 30617.0 35884.0 True False 62845.30554836187 99984.41129934594 58627.34324734431 45759.10290807046 44679.04524104709 26523.102684660687 52402.619021652245 35188.44204031644 31064.715703326692 42389.48514241229 1.48256826751318 2.358707848501508 1.3830633481482282 1.0794918304465733 1.0540124535823627 0.625700043195932 1.23621739791365 0.8301219493961032 0.7328401276628214 1.0 15.37141882324844 -5.586600858148816 2.7554885864661363 0.9268180707940044 1.9237803056051164 0.6902798373753736 0.26181857111595874 0.1340107477196333 2.0450826724611546 0.07034854172075497 0.14569657411136303 2.5905927265614692e-06 5.586600858148816 0.996962234811112 YPSSIS(ph)SSPQK ddPTM_PC-9_Lapatinib_30min_R1 1 YPSSISSSPQK 11 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 YPS(0.009)S(0.009)IS(0.467)S(0.309)S(0.207)PQK 87.713 0.010223000000000001 54830000.0 14213.0 32508.0 23852.0 28496.0 34207.0 28455.0 34458.0 36663.0 22566.0 26889.0 True False 14010.320013655019 32432.72972328555 21890.980631382597 30591.690899869325 32195.01151354957 27238.045981844763 36242.066635711126 38366.49682486185 20024.379449485357 31536.72782265964 0.44425408027234775 1.0284113781767212 0.6941424219558245 0.970033767355176 1.020873557161404 0.8636928388706768 1.1492018715293166 1.2165655562177544 0.6349542527711934 1.0 14.9447453567698 -4.756624176821156 24.979416600174705 0.9577542934878208 0.4442532902999136 0.43937570011084404 0.17236185712065116 139.52469549538196 723714.5710685732 0.04242216895137166 0.3384330416856733 1.7513615998214063e-05 4.756624176821156 -0.5135010031879073 YPSSIS(ph)SSPQKDLTQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YPSSISSSPQKDLTQAK 17 1 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 YPS(0.006)S(0.01)IS(0.347)S(0.347)S(0.289)PQKDLTQAK 55.536 0.024488 10240000.0 39537.0 49251.0 37061.0 43869.0 45842.0 41409.0 46532.0 27222.0 33740.0 34442.0 True False 46229.83320865505 54140.31379148033 37944.67479462518 41411.16215521698 36859.58917955047 39237.43914362166 42124.15209749372 26507.45134409314 34233.38367019115 40686.061957278034 1.1362572582521797 1.3306845437223633 0.9326209755682076 1.0178218329092732 0.9059512620871121 0.9643951086940417 1.0353460146063225 0.6515118462909241 0.8414032232005533 1.0 15.312247026890276 -5.40170683307176 0.7331937094262613 0.8709670467193271 1.3136779427271166 0.46888792636189025 0.1235372747210279 1.2220083202937044 0.8722415376720308 0.05788314558934756 0.390512577073523 3.965456288010685e-06 5.40170683307176 0.44271089600778946 YPSSIS(ph)SSPQKDLTQAK ddPTM_PC-9_Lapatinib_30min_R1 1 YPSSISSSPQKDLTQAK 17 1 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 YPS(0.013)S(0.011)IS(0.504)S(0.084)S(0.388)PQKDLTQAK 82.663 0.0020332 175200000.0 113740.0 179670.0 145350.0 143310.0 169770.0 156450.0 161170.0 203620.0 155560.0 149720.0 True False 112118.04674263867 179253.98515389155 133399.88406722536 153849.49546814567 159784.46238066218 149758.99820276262 169514.5939891336 213080.92855135555 138039.19468057904 175598.90251064036 0.638489450330391 1.0208149515230012 0.7596851811710044 0.876141554807401 0.9099399830871955 0.8528470056564734 0.9653511016611389 1.2134525074178295 0.7861051106069106 1.0 17.42192430252532 -7.343899482689296 4.272358886016549 1.0142064174798588 0.8515778367553648 0.22439801457501563 0.13385417307936975 0.3256112087094891 10.940099482887527 0.05470296369407447 0.03615532583120317 4.530024150266133e-08 7.343899482689296 -0.16262858072449404 YPSSISS(ph)SPQK ddPTM_PC-9_AZD4547_30min_R2 1 YPSSISSSPQK 11 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 YPSSISS(0.631)S(0.369)PQK 145.23 0.00019789 15928000.0 45645.0 54899.0 43833.0 34102.0 31005.0 55666.0 56710.0 46383.0 55073.0 34424.0 True False 60159.16052502002 72644.02814154235 43251.74578002658 26240.310770647884 26700.49093525682 52185.196220153004 61757.08013817298 39215.57312530625 57984.046346242154 33218.82623785013 1.810995972412583 2.1868330813799326 1.3020251067975652 0.7899228763462208 0.8037758692639717 1.570952442645076 1.8590988042740009 1.1805225399753383 1.7455176149533569 1.0 15.019713477210075 -10.975848072988702 6.700774367600695 0.9999018936058368 1.4541783424948895 0.09476746555244808 0.43461177351974484 0.00070227656978585 5.733203822349066e-05 0.4639483940551664 0.11249997209744561 1.057187274935804e-11 10.975848072988702 0.4542764488890527 YPSSISS(ph)SPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YPSSISSSPQK 11 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 YPSSIS(0.021)S(0.489)S(0.489)PQK;YPSSIS(0.012)S(0.494)S(0.494)PQK 152.4 0.000388 58313000.0 153535.0 278094.0 185483.0 134487.0 148897.0 107701.0 172933.0 86482.0 93481.0 101382.0 True False 179525.44304552313 305701.33446078055 189905.61816819504 126952.12940273684 119721.70171605804 102052.96996322535 156551.53431350196 84211.93913525339 94847.98277632291 119761.7540605298 1.499021490239594 2.552578966956959 1.5856950297522634 1.0600389949079478 0.9996655664841756 0.8521332270371215 1.3071913946281877 0.703162205629446 0.7919722245249096 1.0 16.86980773117203 -5.637098712680147 3.0917002584994426 0.9517555933507217 2.0387690428760985 0.7000434490701206 0.28462920979530315 0.12187981832212477 2.3092539428334957 0.07638936376365728 0.14613690327601875 2.3062229377087956e-06 5.637098712680147 1.0870134495253767 YPSSISS(ph)SPQK ddPTM_PC-9_Lapatinib_30min_R1 1 YPSSISSSPQK 11 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 YPS(0.001)S(0.001)IS(0.34)S(0.4)S(0.257)PQK 113.95 0.0015065 17470000.0 18521.0 45744.0 31788.0 33877.0 57394.0 42406.0 57916.0 56285.0 36377.0 35943.0 True False 18256.88714366457 45638.08257850301 29174.51334522847 36368.42759035915 54018.19776094551 40592.39423321416 60914.60709483562 58900.20657849459 32279.83919320789 42155.69965896301 0.4330822947160563 1.0826076413797485 0.6920656893670007 0.8627167354492387 1.2813972534663018 0.9629159179329037 1.4449910115982183 1.3972062391323974 0.7657289394874188 1.0 15.363440083405047 -6.126247245222428 4.707448770554674 1.1670349264371511 0.77147117507023 0.364107624974609 0.2435129388412767 0.24913779504552444 8.461287382046644 0.07094005837521176 0.09329679816157231 7.477436864678376e-07 6.126247245222428 -0.3955637513669211 YPSSISS(ph)SPQKDLTQAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YPSSISSSPQKDLTQAK 17 1 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 Y(0.002)PS(0.049)S(0.044)IS(0.269)S(0.338)S(0.297)PQKDLTQAK;Y(0.019)PS(0.041)S(0.036)IS(0.011)S(0.446)S(0.446)PQKDLT(0.001)QAK 55.206 0.025009 157414000.0 134904.0 141452.0 134998.0 150193.0 155111.0 117606.0 170538.0 126258.0 131672.0 118239.0 True False 157740.58272454693 155494.41973629914 138216.8643027659 141778.17314227574 124718.11302363029 111438.53432646945 154383.40605180044 122943.86128140893 133597.4539010493 139674.79472059105 1.1293417902642717 1.1132604135724993 0.9895619648431084 1.015059112317955 0.8929178186595479 0.7978428359203525 1.1053061245633677 0.8802150848143282 0.9564893520574058 1.0 17.091712174407988 -5.373626647862462 1.4316468423744377 0.9384347397685949 1.1451471675161113 0.4295714232116725 0.07853250710424298 0.4950274904826192 1.7322139391747464 0.024235481275107825 0.10630043716521224 4.2303212816413805e-06 5.373626647862462 0.20671242774751641 YPSSISSS(ph)PQK ddPTM_PC-9_AZD4547_30min_R2 2 YPSSISSSPQK 11 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 YPSSIS(0.005)S(0.11)S(0.885)PQK;YPSSIS(0.004)S(0.087)S(0.909)PQK 161.87 0.0013618 57366000.0 86593.0 108022.0 83955.0 63908.0 73252.0 97393.0 99448.0 106724.0 93611.0 76329.0 True False 114127.77275370929 142937.99901465751 82841.70184477755 49174.99796875741 63082.22422155894 91303.00031382455 108298.67934369651 90232.25807354394 98559.08634935571 73656.7449427396 1.5494544707674995 1.9405961955796012 1.124699467905869 0.6676238273492239 0.8564351339527528 1.2395741949335808 1.4703158472165363 1.2250372745047322 1.338086368410321 1.0 16.168530022256412 -5.273532108332166 24.274254035712 1.1151536220338873 1.7450253150743382 0.5310369346541308 0.2367403081336827 376.18521490833473 755133.9271251612 0.0692984914475532 0.14613643455958827 5.326818405443198e-06 5.273532108332166 0.6298716930404509 YPSSISSS(ph)PQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YPSSISSSPQK 11 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 YPSSISS(0.035)S(0.965)PQK 190.78 0.00045332 19219000.0 50872.0 96671.0 71636.0 52066.0 67326.0 35174.0 57069.0 28445.0 40427.0 39604.0 True False 59483.62483220024 106267.85800361785 73344.07392104303 49148.91082024952 54133.95360373486 33329.41351971188 51663.01117622002 27698.348889968776 41018.16839463002 46783.89169490847 1.2714552525922913 2.2714625516111795 1.5677206676037414 1.0505519964171437 1.1571066801530387 0.7124121639358864 1.1042905860232775 0.5920488417380466 0.8767583650826137 1.0 15.513724256105496 -5.758521896583894 2.593056917279325 0.8974406312449166 1.804749300797737 0.631319095398279 0.27544167004318554 0.1576513323304765 2.161666951300196 0.07758573401103994 0.1408448944160494 1.7437254387965912e-06 5.758521896583894 0.9073086695528205 YPSSISSS(ph)PQK ddPTM_PC-9_Lapatinib_30min_R1 1 YPSSISSSPQK 11 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 YPSSIS(0.001)S(0.022)S(0.977)PQK 180.61 0.001766 54766000.0 39823.0 68356.0 72931.0 64692.0 93728.0 73742.0 92274.0 97227.0 67253.0 80691.0 True False 39255.116717356235 68197.72588177996 66934.89470180121 69449.66548618568 88215.10331633805 70588.2265609979 97051.4962198504 101744.52136461387 59678.25893451386 94638.3318360008 0.41479087760529854 0.7206142010190978 0.7072704410913857 0.7338428746455012 0.932128679837747 0.7458735291670245 1.0254988051567877 1.0750878570104916 0.6305928874351948 1.0 16.53013702346025 -4.422721683297707 0.5150629604495125 0.9254540098705651 1.9524188181805938e-16 0.5384625691498599 0.1329983015009875 4.903134760714426 0.7595826122782333 0.07718457467238571 2.9589645218689333 3.778142348156036e-05 4.422721683297707 -0.9254540098705649 YPSSISSS(ph)PQKDLTQAK ddPTM_PC-9_AZD4547_30min_R2 1 YPSSISSSPQKDLTQAK 17 1 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 YPS(0.017)S(0.028)IS(0.162)S(0.162)S(0.631)PQKDLTQAK 70.986 0.006596600000000001 198040000.0 78213.0 95411.0 96342.0 81940.0 87227.0 82947.0 88987.0 96686.0 85534.0 76547.0 True False 103083.10706853731 126250.73988620333 95064.44213125536 63049.998960380246 75117.03669761798 77760.31097749145 96906.67060933853 81745.40032325134 90055.15261887807 73867.11282909331 1.3955209987297215 1.709160342821443 1.2869657211485497 0.8535598122842479 1.0169212498045865 1.0527054327601222 1.311905486729283 1.106654872411029 1.2191508395250144 1.0 16.172644569106048 -5.5039476385680395 6.7773310934664925 1.0884809412850127 1.5418997298743764 0.6560129065533693 0.13649902759806182 0.09929487036734018 19.972044192185404 0.03738236742952489 0.07340029882472486 3.1336635168613905e-06 5.5039476385680395 0.4534187885893637 YQAQSSTEQTLLSPS(ph)EKPR ddPTM_PC-9_AZD4547_30min_R2 1 YQAQSSTEQTLLSPSEKPR 19 1 Q8WV44-3;Q8WV44 Q8WV44-3 TRIM41 E3 ubiquitin-protein ligase TRIM41 1 YQAQSSTEQT(0.004)LLS(0.434)PS(0.562)EKPR 61.038999999999994 0.0086697 12234000.0 16469.0 16779.0 17391.0 20847.0 17907.0 17497.0 18088.0 18297.0 17141.0 17115.0 True False 21705.799423519646 22202.4836187715 17160.383976922465 16041.0462329393 15420.922147319596 16402.909824022136 19697.796958900955 15469.619073232187 18047.038265954932 16515.809059400566 1.3142437857844458 1.3443170442887966 1.0390277530579113 0.9712540375858222 0.9337067346720277 0.9931641716750067 1.1926631561345913 0.9366552384805573 1.092712939526436 1.0 14.011560024158966 -5.279717707769331 6.239911867718524 1.0172656633672876 1.3306741155255422 0.7403835971115894 0.07329931424595754 0.07225494005811109 12.11585179391981 0.019431108868538282 0.04389555561834836 5.251486969769741e-06 5.279717707769331 0.3134084521582545 YQAQSSTEQTLLSPS(ph)EKPR ddPTM_PC-9_Lapatinib_30min_R1 1 YQAQSSTEQTLLSPSEKPR 19 1 Q8WV44-3;Q8WV44 Q8WV44-3 TRIM41 E3 ubiquitin-protein ligase TRIM41 1 YQAQSSTEQT(0.002)LLS(0.192)PS(0.805)EKPR 83.758 0.00067883 6860600.0 23725.0 23792.0 16785.0 23136.0 28070.0 25541.0 25678.0 18365.0 24569.0 24032.0 True False 23386.677149367846 23736.91108577613 15405.002091973707 24837.49861943349 26418.97778774333 24448.67096897898 27007.481196581037 19218.30494472867 21801.780496960295 28185.899179372856 0.8297296815168771 0.8421555379417306 0.5465499608132947 0.8812029895292534 0.9373118671721282 0.8674078770164312 0.9581912226644799 0.6818411157446097 0.7734995558671188 1.0 14.782685972252265 YQAVTATLEEK ddPTM_PC-9_Lapatinib_30min_R1 2 YQAVTATLEEK 11 0 P40429;M0QYS1;Q8J015;Q6NVV1 P40429 RPL13A;RPL13a;RPL13AP3 60S ribosomal protein L13a;Putative 60S ribosomal protein L13a protein RPL13AP3 0 ; 145.23 0.00091178 19418500.0 84945.0 72457.0 75161.0 75115.0 77559.0 64223.0 93612.0 75625.0 79197.0 80403.0 False True 83733.66872299496 72289.23026824491 68981.5527098501 80639.20767629454 72997.13210686097 61476.33200112517 98458.77131296629 79138.81358263566 70276.99987861788 94300.5514197369 0.8879446351304122 0.7665833251226878 0.7315074161423452 0.8551297575913954 0.7740901936187705 0.6519191147408105 1.0440953931936297 0.8392189906757224 0.7452448455556863 1.0 16.524978586591857 -7.2541886802941775 24.999904328151256 0.8937413908749584 0.7785833716929779 0.2927391980091866 0.09755232346552216 839.5295051883293 2894643.644701791 0.03781978657116381 0.028699291399704018 5.5694373080432117e-08 7.2541886802941775 -0.11515801918198054 YQDEVFGGFVTEPQEES(ph)EEEVEEPEER ddPTM_PC-9_AZD4547_30min_R2 10 YQDEVFGGFVTEPQEESEEEVEEPEER 27 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 1 YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVT(0.001)EPQEES(0.999)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER 169.91 7.5626e-14 119110200.0 296860.5 286691.81 383763.75 417947.1 397705.99 404084.78 327359.2 427942.26 355792.8 349353.19999999995 True False 391255.9639180132 379359.3310185923 378674.7919282205 321595.8533133262 342491.37819359207 378817.29482767486 356493.5346211991 361813.61685183825 374599.2810426027 337122.45080283843 1.1605752241841467 1.1252864652448067 1.1232559297858313 0.9539437452102745 1.01592574857583 1.123678633462537 1.0574600824484681 1.0732409425423883 1.1111668183193237 1.0 18.3629131818046 -5.549920536158197 24.99869944688605 1.0520674005036503 1.1382660182128048 0.4138022696913555 0.04838384458384418 220.20363277437912 203565.52349709533 0.013779666806549472 0.023867792028297183 2.8188986643330593e-06 5.549920536158197 0.08619861770915449 YQDEVFGGFVTEPQEES(ph)EEEVEEPEER ddPTM_PC-9_LapatinibAZD4547_30min_R1 16 YQDEVFGGFVTEPQEESEEEVEEPEER 27 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 1 YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVT(0.002)EPQEES(0.998)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER 174.98 3.0889e-29 91472660.0 227450.93 223024.6 286158.10000000003 278697.3 301190.5 270875.4 270923.4 266545.87 249795.2 220253.38000000003 True False 265953.88008835976 245165.00836976705 292981.19436463807 263082.79382983694 242174.38363909454 256670.21717511123 245259.57423644225 259549.32334119402 253447.98223391076 260183.57426920312 1.0221778251581182 0.9422770405794454 1.126055690439168 1.0111429769107334 0.930782753366763 0.9864966222254418 0.9426404988298012 0.9975622945076738 0.9741121550266534 1.0 17.98917036013445 -6.013947474863356 24.73959295871183 0.9710640004309508 1.0292506037916602 0.25162292220150617 0.0460467509456566 795.9404464714796 1411818.6187974268 0.01328291174955905 0.017910367903473477 9.683949703496936e-07 6.013947474863356 0.058186603360709466 YQDEVFGGFVTEPQEES(ph)EEEVEEPEER ddPTM_PC-9_Lapatinib_30min_R1 12 YQDEVFGGFVTEPQEESEEEVEEPEER 27 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 1 YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER 173.74 1.0017e-21 100459500.0 241558.99999999997 229923.4 266288.39999999997 222763.8 267269.9 261890.1 224028.89999999997 212713.4 258059.19999999998 210891.7 True False 238114.32436350506 229391.02649375203 244395.19565495008 239146.59297025253 251549.60995484074 250689.6709186411 235628.02026017357 222596.84111244505 228993.85541215248 247344.04934947295 0.9626846693492627 0.9274167989772212 0.9880779274768142 0.9668580812807903 1.017002877637156 1.0135261858046203 0.952632662398335 0.8999482368704067 0.9258110555496185 1.0 17.91615966571716 -10.452002437362449 5.54954039997965 1.0000000426935962 0.9625687722493086 0.09332374903722818 0.035826955106749006 2.1236868558108984e-08 4.078177556868052e-09 0.03894376501466334 0.009445239692467387 3.531811876507697e-11 10.452002437362449 -0.03743127044428762 YQDVY(ph)VELSHIK ddPTM_PC-9_AZD4547_30min_R2 1 YQDVYVELSHIK 12 0 Q9H2D6-5;Q9H2D6-7;Q9H2D6-3;Q9H2D6-2;Q9H2D6 Q9H2D6-5 TRIOBP TRIO and F-actin-binding protein 1 Y(0.003)QDVY(0.997)VELSHIK 102.9 0.015893 0.0 24203.0 23856.0 29732.0 31484.0 32003.0 28602.0 30380.0 35374.0 33203.0 32517.0 True False 31899.050546326183 31566.98547049367 29337.734253456318 24225.850222951092 27559.935861990783 26813.512418510683 33083.76114614168 29907.761113653327 34958.042794732064 31378.58972740452 1.0165864949139864 1.0060039582634466 0.9349602550121677 0.7720503194505719 0.8783038403386654 0.8545161733350011 1.0543418755766436 0.9531263633410955 1.1140731020234929 1.0 14.937492893136522 -7.269179185828183 24.798580876895908 1.0264792033048578 0.9081173403281915 0.36918887067477557 0.07672995932525438 671.2675741231559 2150751.686097462 0.034500255507404355 0.02375950901173454 5.380477432634937e-08 7.269179185828183 -0.11836186297666629 YQEDSDPERS(ph)DYEEQQLQKEEEAR ddPTM_PC-9_Lapatinib_30min_R1 1 YQEDSDPERSDYEEQQLQKEEEAR 24 2 Q6P6C2-3;Q6P6C2;Q6P6C2-1 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 Y(0.019)QEDS(0.044)DPERS(0.563)DY(0.374)EEQQLQKEEEAR 51.431000000000004 0.007134699999999999 9274800.0 13765.0 14238.0 20465.0 18025.0 16606.0 17797.0 15328.0 18299.0 19351.0 9586.6 True False 13568.708575808161 14205.032785780108 18782.446697184503 19350.618629637316 15629.26772865215 17035.863796833284 16121.60883951999 19149.23834378382 17171.48660493625 11243.63103665844 1.206790629430039 1.26338482110151 1.6704965358563177 1.721029315756366 1.3900551945981592 1.5151567799841528 1.433843638852744 1.703118706167976 1.527218969472654 1.0 13.456820396658815 -10.795233099359884 6.447234736832642 0.9999898277028499 1.4997167284110877 0.4386724095731842 0.16689383534537638 2.590940375815157e-05 2.9237944856282758e-06 0.17157228666344368 0.04161154572567833 1.602385109900268e-11 10.795233099359884 0.4997269007082378 YQELINDIAR ddPTM_PC-9_Lapatinib_30min_R1 1 YQELINDIAR 10 0 P46940;H0YLE8 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 0 126.71 0.0015536 1878600.0 7768.8 6157.5 9052.8 7969.7 8301.0 9611.9 7710.7 7770.7 9148.8 6267.2 False True 7658.015487376563 6143.242687065671 8308.51372881856 8555.818324139833 7812.7515003939225 9200.821443433275 8109.922317255141 8131.755090335051 8118.365802865006 7350.47716948092 1.0418392317675018 0.8357610731140462 1.1303366485260842 1.1639813479951306 1.0628903838831525 1.2517311776213602 1.1033191628602599 1.10628941534544 1.1044678618379158 1.0 12.843622192801377 -5.281732158603129 24.715328849914687 1.123473566364327 0.9388001573653938 0.45406136961277865 0.07703951141846035 474.7846949712826 578257.4304861812 0.018857659155058108 0.03933742615472165 5.227184645189349e-06 5.281732158603129 -0.18467340899893314 YQEQGGEAS(ph)PQR ddPTM_PC-9_AZD4547_30min_R2 2 YQEQGGEASPQR 12 0 H0Y5J4;Q9UJU6-5;Q9UJU6 H0Y5J4 DBNL Drebrin-like protein 1 YQEQGGEAS(1)PQR;YQEQGGEAS(1)PQR 114.21 0.00077932 59118000.0 18577.3 16820.9 19671.4 24489.0 19052.3 22528.0 20354.0 29488.0 18681.3 19627.8 True False 24484.494968155414 22257.92697437234 19410.544382935575 18843.439401278392 16407.21701163663 21119.320598706672 22165.466569077278 24931.30716682903 19668.755379370174 18940.63669623736 1.2926965107260286 1.175141434331718 1.0248094979189144 0.9948683195545228 0.8662442173813509 1.1150269622616285 1.1702598452501094 1.316286646888789 1.0384421439896714 1.0 14.209197207877668 -6.995247619555542 24.98664094969891 1.1554671226592113 1.0618685361063576 0.03149054938796525 0.13198113297799527 350.39203080185325 1842242.7041105153 0.049461365576298426 0.04345631387721739 1.0110028513569545e-07 6.995247619555542 -0.09359858655285369 YQEQGGEAS(ph)PQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YQEQGGEASPQR 12 0 H0Y5J4;Q9UJU6-5;Q9UJU6 H0Y5J4 DBNL Drebrin-like protein 1 YQEQGGEAS(1)PQR;YQEQGGEAS(1)PQR 88.22399999999999 0.008151 57985000.0 20785.1 24434.0 19828.8 19379.9 23608.6 18093.699999999997 21705.0 19112.7 17948.3 13336.5 True False 24303.60690556228 26859.646041319567 20301.593793142758 18294.107033483528 18982.66430575314 17144.834519861575 19648.945269408166 18611.01187657957 18210.759932652392 15754.30187832409 1.542664796781693 1.7049086813726106 1.288638109764493 1.1612134371154768 1.204919421524534 1.088263678852738 1.2472114233409866 1.1813288852986847 1.1559230027011274 1.0 13.943458205057235 -5.411184344912496 3.6181464193366786 1.1622872498899852 1.622687342019034 0.8595043831020567 0.07549511050472309 0.07475147946949466 1.755113788771526 0.019189466696473013 0.04352488190314846 3.8798564282647705e-06 5.411184344912496 0.46040009212904875 YQEQGGEAS(ph)PQR ddPTM_PC-9_Lapatinib_30min_R1 2 YQEQGGEASPQR 12 0 H0Y5J4;Q9UJU6-5;Q9UJU6 H0Y5J4 DBNL Drebrin-like protein 1 YQEQGGEAS(1)PQR;YQEQGGEAS(1)PQR 115.09 0.00073868 59573000.0 16387.2 21185.0 20039.4 19165.3 24265.0 19303.8 23794.0 18717.0 16884.2 16040.7 True False 16153.515522955571 21135.947434102534 18391.837886321002 20574.780095566613 22837.780406825488 18478.221473355658 25025.93689506386 19586.660149767857 14982.523597491838 18813.313622110767 0.8586214979146891 1.123456923041034 0.9775969430874518 1.0936287200031387 1.2139158930505936 0.982188563084321 1.3302248289557863 1.0411063432625818 0.7963787718864843 1.0 14.19946635521326 -4.752878859068173 24.761880423671343 1.0723172587944847 0.8586210422430071 0.16105953749971258 0.13750528133203357 524.3552016773746 1516602.2544210746 0.03392335481264519 0.3825150472337957 1.7665305032248085e-05 4.752878859068173 -0.21369621655147764 YQEQGGEAS(ph)PQRTWEQQQEVVSR ddPTM_PC-9_AZD4547_30min_R2 1 YQEQGGEASPQRTWEQQQEVVSR 23 1 H0Y5J4;Q9UJU6-5;Q9UJU6 H0Y5J4 DBNL Drebrin-like protein 1 Y(0.004)QEQGGEAS(0.99)PQRT(0.006)WEQQQEVVSR 79.029 0.00011322 14427000.0 7693.3 2367.1 11968.0 18031.0 12814.0 7520.2 4448.8 8157.1 3423.9 10619.0 True False 10139.609369419128 3132.2187838365853 11809.296500247721 13874.231526173011 11034.997285740403 7049.960705184391 4844.73458153243 6896.607626510475 3604.8803639696116 10247.23204217204 0.9894973908749216 0.30566486354032724 1.1524376974823125 1.353949190286139 1.07687590564226 0.6879868315824784 0.4727847053325361 0.6730215143101849 0.35179064445246117 1.0 13.322946644566402 -6.893514482586154 5.276626462907375 0.5952224761887098 0.9677610466713524 0.2447728929453632 0.29652299081018096 0.3153255956743451 13.509941076052588 0.11209832640605473 0.0986938606278906 1.277866595343884e-07 6.893514482586154 0.3725385704826426 YQEQGGEAS(ph)PQRTWEQQQEVVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YQEQGGEASPQRTWEQQQEVVSR 23 1 H0Y5J4;Q9UJU6-5;Q9UJU6 H0Y5J4 DBNL Drebrin-like protein 1 Y(0.056)QEQGGEAS(0.876)PQRT(0.068)WEQQQEVVSR;Y(0.008)QEQGGEAS(0.716)PQRT(0.274)WEQQQEVVS(0.001)R 68.458 0.00061777 20829000.0 10449.4 1704.2 5863.2 19542.9 17053.7 16456.5 11270.7 20121.2 14437.0 13071.0 True False 12218.277034942457 1873.381713334568 6003.0009243098275 18447.974671936663 13712.149906009767 15593.49216998745 10203.057703198281 19593.039820173657 14648.113812879363 15440.66883002093 0.7913049084497394 0.12132775684510479 0.3887785555401806 1.194765257581893 0.8880541417577428 1.0098974559747949 0.6607911752734905 1.2689242956936795 0.9486709399789327 1.0 13.914447625475121 -5.74964777156526 24.997989547617024 0.9892073630971858 0.4025558936668502 0.5835337914773409 0.21706625341834068 144.3459621893904 306008.0209357594 0.05681015656318511 0.09738679211046812 1.7797222435732865e-06 5.74964777156526 -0.5866514694303356 YQEQGGEAS(ph)PQRTWEQQQEVVSR ddPTM_PC-9_Lapatinib_30min_R1 1 YQEQGGEASPQRTWEQQQEVVSR 23 1 H0Y5J4;Q9UJU6-5;Q9UJU6 H0Y5J4 DBNL Drebrin-like protein 1 Y(0.005)QEQGGEAS(0.668)PQRT(0.328)WEQQQEVVSR 65.915 0.00080401 12826000.0 6257.6 3602.1 3587.7 4194.2 2546.9 1902.5 2312.4 2320.5 3600.8 2301.7 True False 6168.365476496701 3593.7595587623637 3292.733154922495 4502.6554594410445 2397.096349398059 1821.13450994411 2432.1247573399046 2428.318901401736 3195.2399858950157 2699.5457781775335 2.2849642063343603 1.3312460147234528 1.2197359946773798 1.6679307666643062 0.887962844999925 0.6746077524099481 0.9009385123232971 0.8995286988765558 1.1836213379763931 1.0 11.398500966494534 -1.5228787490243263 0.5731903610121943 0.940939377953075 66.37164905123093 0.7129653493743608 0.24000795565959065 86.52554951996478 0.7348521822895527 0.12104033942562771 7029.62388561097 0.029999999741374423 1.5228787490243263 65.43070967327786 up YQEQGGEAS(ph)PQSR ddPTM_PC-9_AZD4547_30min_R2 2 YQEQGGEASPQSR 13 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3 B4DDD6 DBNL Drebrin-like protein 1 YQEQGGEAS(0.995)PQS(0.005)R;YQEQGGEAS(1)PQSR 146.84 8.0155e-05 29465000.0 19485.2 16327.8 23498.3 33880.0 27809.0 23626.4 21440.0 24774.6 20196.3 20793.1 True False 25681.088282662287 21605.442042468407 23186.69718848352 26069.48944078205 23948.200368281156 22149.037473068343 23348.118465216525 20946.254833672065 21263.835186436376 20065.13989792708 1.2798858325087177 1.0767650837411034 1.1555711700210434 1.2992428447247095 1.193522721003068 1.103856618281368 1.16361603178399 1.0439127232716683 1.0597401909285034 1.0 14.292403594443437 -7.725370417917395 0.9363228831584658 1.0087205126913048 1.1936541188950598 0.5366529650482332 0.0642576772658441 0.47806088952438175 0.7634146420984425 0.058269562443866746 0.024754683158894838 1.882043174771056e-08 7.725370417917395 0.18493360620375499 YQEQGGEAS(ph)PQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YQEQGGEASPQSR 13 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3 B4DDD6 DBNL Drebrin-like protein 1 YQEQGGEAS(0.97)PQS(0.03)R 111.81 0.00052495 13788000.0 11588.0 9276.3 13062.0 10175.0 12080.0 11632.0 12082.0 9796.6 10325.0 10688.0 True False 13549.619526567387 10197.189759069028 13373.447617910857 9604.927737795078 9713.010717005585 11021.9974430343 10937.505493894934 9539.449630355708 10475.98359201907 12625.64979383855 1.0731819548154855 0.8076566296053423 1.059228462398604 0.7607472007090189 0.7693077881619714 0.8729845689536829 0.8662924817725067 0.7555610828847051 0.8297381729320151 1.0 13.62407001931285 -5.769468400432823 24.999954943354457 0.8261683270565572 0.962785784193264 0.31175488126756346 0.09596037637194038 206.14699919106886 641881.0861269834 0.025411081249218582 0.03845081466933392 1.700323665868719e-06 5.769468400432823 0.1366174571367068 YQEQGGEAS(ph)PQSR ddPTM_PC-9_Lapatinib_30min_R1 2 YQEQGGEASPQSR 13 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3 B4DDD6 DBNL Drebrin-like protein 1 YQEQGGEAS(0.991)PQS(0.009)R;YQEQGGEAS(0.875)PQS(0.125)R 125.33 0.00014282 26167000.0 16994.9 15173.800000000001 18185.0 15326.9 16013.3 15248.1 16025.3 13625.1 17629.1 10008.2 True False 16752.54960951703 15138.665998375489 16689.899496129987 16454.09135503957 15071.429177359101 14595.974308057186 16855.01162160489 14258.171886872997 15643.525115347098 11738.104034911754 1.4271938261657242 1.2897028304869085 1.4218564979906876 1.4017673813506348 1.2839747486078918 1.2434694959803974 1.435922834852571 1.214691217974044 1.3327131084219177 1.0 13.518911779451887 -13.538762745820868 0.20412071707147322 9.685241541212785e-10 1.39338899432786 0.6827232011144814 0.0715827234287681 51.890211952068505 0.7381376810613641 21.482909498027617 0.16269977140786943 2.892259486247078e-14 13.538762745820868 1.3933889933593357 YQEQGGEASPQRT(ph)WEQQQEVVSR ddPTM_PC-9_Lapatinib_30min_R1 1 YQEQGGEASPQRTWEQQQEVVSR 23 1 H0Y5J4;Q9UJU6-5;Q9UJU6 H0Y5J4 DBNL Drebrin-like protein 1 Y(0.003)QEQGGEAS(0.278)PQRT(0.719)WEQQQEVVSR 71.042 0.0006546 11019000.0 10568.0 2575.0 5001.7 4318.3 1955.6 2224.8 2111.0 2188.4 6270.8 1186.1 True False 10417.29838206616 2569.0377457075297 4590.47953312034 4635.88218742651 1840.5754528575294 2129.650490262107 2220.297250797672 2290.0810531469783 5564.516469548562 1391.1158046210942 7.488448012351909 1.846746142322258 3.2998543456061693 3.3324919262844626 1.3230929062436014 1.5308937495984896 1.596054939079947 1.6462188450017217 4.000038279389831 1.0 10.442026807919952 -4.759102613053635 24.995517819374 2.201711632292924 7.488454900322732 0.7344207094907681 0.9584380473160488 32.75190816033362 350256.9747894356 0.24214119052508534 1.5762620035286665 1.7413953760868156e-05 4.759102613053635 5.286743268029808 YQEQGGEASPQS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YQEQGGEASPQSR 13 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3 B4DDD6 DBNL Drebrin-like protein 1 YQEQGGEAS(0.31)PQS(0.69)R 123.68 0.00016299999999999998 12358000.0 10066.0 9086.7 7309.6 7383.8 8593.8 8383.8 10591.0 9114.7 7326.9 6709.0 True False 11769.97498743764 9988.767524091782 7483.888585812372 6970.109624602588 6909.90658110948 7944.138769163601 9587.743807800136 8875.448782822934 7434.042051367026 7925.288591585225 1.4851162644013443 1.2603664092052724 0.9443048665456152 0.8794770744377927 0.8718807525124271 1.0023784846899317 1.2097658901632988 1.119889664616952 0.9380153120556662 1.0 12.952247755190886 -5.012163590313986 2.9622507331838603 0.9999898935362517 1.4796134713358022 0.7167658636684311 0.09939618571186808 0.16804364429292437 2.7785594714350204 0.030177213126075235 0.14826380539844464 9.723808777532764e-06 5.012163590313986 0.47962357779955056 YQEVDRR ddPTM_PC-9_AZD4547_30min_R2 1 YQEVDRR 7 1 Q96MU7;Q96MU7-2 Q96MU7 YTHDC1 YTH domain-containing protein 1 0 77.923 0.018404 2767400.0 6492.0 6424.7 7604.1 12937.0 11444.0 7938.5 6148.5 10400.0 6166.4 7284.6 False True 8556.320958011389 8501.358633143891 7503.264665569327 9954.574524657542 9855.19813781903 7442.104340058279 6695.704588777227 8792.918968225096 6492.343315044892 7029.568371259671 1.2171900899340893 1.2093713559856138 1.0673862560674934 1.416100391790303 1.401963480163579 1.0586858178213698 0.952505791984691 1.250847634425873 0.9235763808185977 1.0 12.779220392486138 -6.856520810310909 9.303130091324894 1.0463086402164021 1.256952650270458 0.4507293239054233 0.12411163069045304 0.31400986054085595 27.903506915172358 0.04520080383498333 0.039879399040735404 1.3914871166469948e-07 6.856520810310909 0.21064401005405586 YQGVNLYVK ddPTM_PC-9_Lapatinib_30min_R1 2 YQGVNLYVK 9 0 A0A087WTT1;P11940;E7EQV3;P11940-2;E7ERJ7;H0YAR2;H0YAP2;Q4VXU2;Q4VXU2-2;A0A6I8PLA1;A0A6I8PS38 A0A087WTT1 PABPC1;PABPC1L Polyadenylate-binding protein;Polyadenylate-binding protein 1;Polyadenylate-binding protein 1-like 0 ; 117.04 0.008673 10087500.0 68707.0 63852.0 66157.0 61184.0 66994.0 53208.0 59373.0 58063.0 61585.0 55782.0 False True 67727.22558067925 63704.15461705516 60717.82683340515 65683.67546384079 63053.54463527168 50932.41787390603 62447.04342567986 60760.81894940276 54648.64878119988 65423.84437515715 1.0352070598651146 0.9737146330282757 0.928068770848034 1.0039715044440634 0.9637700938774928 0.7784993126030083 0.9544997549760674 0.9287259030665426 0.8353017054123337 1.0 15.997528915766521 -6.547058300702689 24.99926112256334 0.8953652684127607 0.9807757365367386 0.3006286810525095 0.06257173942854113 282.36166590388586 291931.7507725987 0.01994850382236788 0.019949245437974297 2.8375380851518114e-07 6.547058300702689 0.0854104681239779 YQLDKDGVVLFK ddPTM_PC-9_Lapatinib_30min_R1 1 YQLDKDGVVLFK 12 1 P07237;H7BZ94;I3L398;I3L312;I3L3U6 P07237 P4HB Protein disulfide-isomerase 0 107.34 0.0020259 5110700.0 29620.0 26713.0 25324.0 25447.0 24556.0 21173.0 27486.0 23294.0 21213.0 21682.0 False True 29197.613368357266 26651.14768974183 23241.958473466908 27318.4572687035 23111.664358953523 20267.480146673683 28909.090589969106 24376.324278927837 18823.768557207 25429.704810551022 1.1481695751435896 1.0480321296802477 0.9139688661986985 1.0742734716043112 0.9088451687164012 0.7970002128481065 1.1368236794465052 0.9585767691968596 0.7402275684064112 1.0 14.63422709478919 -1.5228788534594009 0.6309260753358065 0.9323766240141641 18.11567067784969 0.26585013229008936 0.11076056626479665 284.5440537009439 1.9721740324424273 0.048121154072688264 6798.050417948954 0.029999992527255975 1.5228788534594009 17.183294053835525 YQPLAS(ph)TASDNDFVTPEPR ddPTM_PC-9_AZD4547_30min_R2 2 YQPLASTASDNDFVTPEPR 19 0 Q15021 Q15021 NCAPD2 Condensin complex subunit 1 1 YQPLAS(0.931)T(0.061)AS(0.007)DNDFVTPEPR;YQPLAS(0.592)T(0.307)AS(0.1)DNDFVTPEPR 138.66 2.195e-09 0.0 7071.4 6317.700000000001 7777.5 10420.7 8057.6 10261.099999999999 6045.700000000001 8082.0 6055.3 7688.4 True False 9319.958105742717 8359.772975642934 7674.365268271773 8018.36861321008 6938.941324300131 9619.471794894758 6583.755587927218 6833.112605884164 6375.370795860041 7419.2314561668245 1.2561891566270005 1.126770747756405 1.0343881726311264 1.0807546119275273 0.9352641665509062 1.29655906433531 0.887390510300745 0.9210000585983226 0.8593033973297689 1.0 12.857054033259818 -7.304066907727459 24.999088693069307 0.910340078875337 1.1075889613221008 0.48536821204229885 0.10257578963667512 440.5789275072012 258377.66467078927 0.042412300356786864 0.028594614902011845 4.9651582196480905e-08 7.304066907727459 0.19724888244676386 YQPLAS(ph)TASDNDFVTPEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YQPLASTASDNDFVTPEPR 19 0 Q15021 Q15021 NCAPD2 Condensin complex subunit 1 1 YQPLAS(0.874)T(0.092)AS(0.034)DNDFVTPEPR 257.06 1.5003999999999997e-65 9065500.0 30538.0 27624.0 29842.0 35834.0 40279.0 40854.0 46471.0 44629.0 45876.0 33136.0 True False 35707.48024700681 30366.32815934402 30553.546456415224 33826.3371553955 32386.61909522085 38711.54432064334 42068.93045909547 43457.53603833418 46546.84971113483 39143.294495568334 0.9122247043117304 0.7757734383543518 0.7805563341091382 0.8641668411233295 0.8273861337575341 0.9889700092828447 1.0747416895084896 1.1102166181554876 1.1891398082602553 1.0 15.25647756505931 -6.980229805810538 1.87209598985526 1.1091456058243696 0.8230831400229602 0.8213080717904093 0.05753914689603946 0.12977989820478464 0.9185389386048393 0.025306798741618786 0.019733462211924152 1.0465746092375957e-07 6.980229805810538 -0.28606246580140937 YQPLAS(ph)TASDNDFVTPEPR ddPTM_PC-9_Lapatinib_30min_R1 1 YQPLASTASDNDFVTPEPR 19 0 Q15021 Q15021 NCAPD2 Condensin complex subunit 1 1 YQPLAS(0.333)T(0.333)AS(0.333)DNDFVTPEPR 237.39 1.1148e-43 15394000.0 29490.0 21024.0 24116.0 29225.0 33315.0 42321.0 43384.0 33935.0 53321.0 28957.0 True False 29069.46719219632 20975.320219710713 22133.275570452053 31374.30399174205 31355.477199810073 40511.029485069485 45630.21124045767 35511.74398580821 47315.4274849778 33962.178867222836 0.8559364611394674 0.6176082018092826 0.6517036394214698 0.9238012706546822 0.9232469248335385 1.1928277524080468 1.3435595937131037 1.045626198620633 1.3931799744050666 1.0 15.051641398514022 -6.391069652439876 1.4556965184219426 1.2110515947504408 0.7086309597125242 0.698842686542851 0.13571555279917888 0.20886582371533094 0.8942953286488066 0.051181052460088944 0.06333973029537464 4.063781487388459e-07 6.391069652439876 -0.5024206350379166 YQPLAST(ph)ASDNDFVTPEPR ddPTM_PC-9_AZD4547_30min_R2 2 YQPLASTASDNDFVTPEPR 19 0 Q15021 Q15021 NCAPD2 Condensin complex subunit 1 1 YQPLAS(0.308)T(0.69)AS(0.002)DNDFVTPEPR;YQPLAS(0.094)T(0.904)AS(0.002)DNDFVTPEPR 230.67 2.6049e-35 31958000.0 24700.7 28901.6 41743.0 56521.0 45605.0 41087.0 33127.0 40267.0 32975.0 38240.0 True False 32555.008793523095 38243.47699840793 41189.46054560831 43490.95669074507 39273.53294960131 38517.82339484469 36075.23882449754 34044.66039360771 34717.99118020326 36901.22923935014 0.8822201716469544 1.0363740663041778 1.1162083593054226 1.1785774508662676 1.0642879318426994 1.0438086803290192 0.9776161815777183 0.9225887889204436 0.9408356278598232 1.0 15.171381255129877 -7.287272103128319 2.7341117012930654 0.9488134446481501 1.0638754028658455 0.2813945080938778 0.07291964793082541 0.3619733618331287 5.38287894204596 0.036472968410338646 0.02409134686957598 5.160929147858561e-08 7.287272103128319 0.11506195821769538 YQPLAST(ph)ASDNDFVTPEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YQPLASTASDNDFVTPEPR 19 0 Q15021 Q15021 NCAPD2 Condensin complex subunit 1 1 YQPLAS(0.033)T(0.791)AS(0.175)DNDFVTPEPR;YQPLAS(0.022)T(0.842)AS(0.013)DNDFVT(0.122)PEPR 212.76 1.0476e-21 9106600.0 27619.0 30968.0 38522.0 33211.0 39091.0 35559.6 34055.7 34360.4 31054.7 25316.3 True False 32294.351199884764 34042.29837961794 39440.51057549856 31350.29534151475 31431.39916709147 33694.791976901884 30829.697554083556 33458.47590785314 31508.816237779625 29905.94478627946 1.079863934434236 1.1383120855367925 1.3188184107660583 1.0482964362288913 1.0510083995577988 1.1266921081309798 1.0308886000561301 1.1187901317601425 1.0535970845581026 1.0 14.868144675384084 YQPLAST(ph)ASDNDFVTPEPR ddPTM_PC-9_Lapatinib_30min_R1 1 YQPLASTASDNDFVTPEPR 19 0 Q15021 Q15021 NCAPD2 Condensin complex subunit 1 1 YQPLAS(0.066)T(0.56)AS(0.374)DNDFVTPEPR 105.77 0.00057203 1573800.0 3350.7 3245.4 3964.4 1512.8 4239.4 5035.3 1511.5 1560.8 4922.4 1290.8 True False 3302.918403556876 3237.88547569678 3638.462335026547 1624.0563585528623 3990.0468269810854 4819.951956857596 1589.7580741737002 1633.3204659805338 4367.987476830047 1513.9130601171146 2.181709432707692 2.1387525882406355 2.4033495917824235 1.072754044692122 2.6355851812735005 3.1837706430016066 1.050098658935354 1.0788733574001812 2.8852300649894285 1.0 10.564066642337574 -11.370269311496076 0.25841386891489254 7.82198701985401e-12 2.182016854759911 0.14850894876567944 0.7382543735558931 58.4380953927335 2.419097323661895 38.150139309007685 1.1177520783191746 4.263150734530498e-12 11.370269311496076 2.1820168547520886 YQPLASTAS(ph)DNDFVTPEPR ddPTM_PC-9_AZD4547_30min_R2 1 YQPLASTASDNDFVTPEPR 19 0 Q15021 Q15021 NCAPD2 Condensin complex subunit 1 1 YQPLAS(0.011)T(0.09)AS(0.897)DNDFVT(0.002)PEPR 138.66 2.195e-09 0.0 4161.7 4067.0 4408.7 8388.0 6797.9 3709.2 4433.9 5108.2 3534.9 8013.6 True False 5485.0340312624785 5381.5782154802855 4350.237757406593 6454.276193308142 5854.128925295354 3477.2631376386203 4828.50851039755 4318.845064758409 3721.7475973586215 7733.046303150003 0.7092979682571133 0.6959195644914394 0.5625516241425522 0.834635658482872 0.7570275278076009 0.449662785055636 0.6243992756684633 0.5584920735569833 0.4812783282886323 1.0 12.916821136158674 -10.646791912670992 4.854649797621151 1.0000205234097432 0.6324259684241788 0.48029684473631706 0.11533261089946921 2.6960263660085866e-05 4.865404508397582e-06 0.11751709277271224 0.028500491723224303 2.2553195643811184e-11 10.646791912670992 -0.3675945549855645 YQPLASTAS(ph)DNDFVTPEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 YQPLASTASDNDFVTPEPR 19 0 Q15021 Q15021 NCAPD2 Condensin complex subunit 1 1 YQPLAS(0.043)T(0.021)AS(0.933)DNDFVT(0.003)PEPR;YQPLAS(0.139)T(0.139)AS(0.624)DNDFVT(0.097)PEPR;YQPLAST(0.014)AS(0.986)DNDFVTPEPR 166.21 8.6247e-08 18457100.0 36174.4 41553.1 47768.8 47681.0 55894.8 59117.8 62675.0 59238.9 56361.3 43603.1 True False 42298.01144303238 45678.21715312909 48907.7893561828 45009.5881538877 44942.615184179114 56017.55849706096 56737.97027229475 57683.94164380278 57185.47738739611 51507.9968680503 0.821193096508656 0.8868179686766785 0.9495183724863435 0.8738368970004835 0.8725366528873189 1.087550708690205 1.1015371150550124 1.119902639420702 1.1102252245197963 1.0 15.652508814684944 -6.76428748551256 24.85323300564121 1.0924429658962054 0.8845489933274133 0.8492411228880054 0.04268696254411566 24.816260660643287 216550.52300737973 0.014656360653638272 0.013495751999950121 1.7207291442829203e-07 6.76428748551256 -0.20789397256879205 YQPLASTAS(ph)DNDFVTPEPR ddPTM_PC-9_Lapatinib_30min_R1 3 YQPLASTASDNDFVTPEPR 19 0 Q15021 Q15021 NCAPD2 Condensin complex subunit 1 1 YQPLAS(0.007)T(0.015)AS(0.978)DNDFVT(0.001)PEPR;Y(0.003)QPLAS(0.067)T(0.04)AS(0.889)DNDFVT(0.002)PEPR;YQPLAS(0.07)T(0.211)AS(0.631)DNDFVT(0.088)PEPR 124.98 3.6367e-05 19918700.0 32607.300000000003 36259.0 37632.1 33931.7 40757.2 38066.1 40306.2 37602.600000000006 41764.1 33936.6 True False 32142.31392255355 36175.044513246336 34538.13400210687 36427.15041083298 38359.94162773824 36438.10163941315 42393.05781624876 39349.75407104027 37060.18726252998 39802.49609232293 0.8075451812870884 0.9088637162186355 0.8677378906587859 0.9151976380159489 0.9637571859503824 0.9154727772573363 1.065085408661732 0.9886252857048835 0.9311020890892849 1.0 15.280571287381125 -5.793249743670298 0.6435941121080522 0.9931115391053361 0.8205347078708204 0.6237892502687532 0.04208232451646619 0.8413084171237686 0.5896756072576302 0.02480327397708718 0.09092648573197751 1.6097196899183834e-06 5.793249743670298 -0.17257683123451573 YQPLASTASDNDFVT(ph)PEPR ddPTM_PC-9_AZD4547_30min_R2 4 YQPLASTASDNDFVTPEPR 19 0 Q15021 Q15021 NCAPD2 Condensin complex subunit 1 1 YQPLASTASDNDFVT(1)PEPR;YQPLASTASDNDFVT(1)PEPR;YQPLASTAS(0.001)DNDFVT(0.999)PEPR;YQPLAST(0.007)AS(0.014)DNDFVT(0.979)PEPR 254.54 5.3578e-65 24891300.0 61072.1 61850.5 75524.0 107367.0 85258.0 75557.0 56461.6 95738.0 60813.1 76523.0 True False 80491.7574214058 81842.46457255053 74522.50241349505 82615.19695361414 73421.39836020408 70832.4088457244 61486.57301938755 80943.8919403782 64027.55631359572 73843.95306178859 1.0900250336551551 1.1083164047849554 1.0091889629898156 1.1187808009748104 0.9942777345461051 0.9592174566610175 0.8326554913431969 1.096147871074139 0.8670656656208662 1.0 16.17219216587531 -6.470090679488576 3.7011221004097274 0.950859009373556 1.0780435428272104 0.4198934734104738 0.07228577452585533 0.23380387500509212 6.471161150985376 0.02276361209364021 0.025072486580958758 3.3877341380073206e-07 6.470090679488576 0.12718453345365432 YQPLASTASDNDFVT(ph)PEPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YQPLASTASDNDFVTPEPR 19 0 Q15021 Q15021 NCAPD2 Condensin complex subunit 1 1 YQPLASTASDNDFVT(1)PEPR;YQPLASTAS(0.01)DNDFVT(0.99)PEPR 233.38 4.2986e-59 6856900.0 44903.0 39667.0 48852.0 52126.0 48944.0 42153.5 40574.3 35280.1 34876.1 28687.2 True False 52504.19102532405 43604.87760992975 50016.81695224171 49205.54921477215 39353.77454744381 39942.89625300432 36730.808571506495 34354.03475735586 35386.09698340111 33887.962272249766 1.5493463609146771 1.2867364894830806 1.4759464304880783 1.4520067279190074 1.1612906739945794 1.1786750685128338 1.083889561621257 1.0137533346313878 1.0442084625542132 1.0 15.048485267828843 -6.580910045733956 1.1637946891608693 1.0310986713943933 1.4453328895059239 0.8501302382107775 0.07522380028648959 0.17380932897948076 0.49782884478539124 0.03535371079964611 0.037997892517904835 2.624762147118173e-07 6.580910045733956 0.4142342181115306 YQPLASTASDNDFVT(ph)PEPR ddPTM_PC-9_Lapatinib_30min_R1 4 YQPLASTASDNDFVTPEPR 19 0 Q15021 Q15021 NCAPD2 Condensin complex subunit 1 1 YQPLASTASDNDFVT(1)PEPR;YQPLASTASDNDFVT(1)PEPR;YQPLASTASDNDFVT(1)PEPR;YQPLASTASDNDFVT(1)PEPR 249.26 1.2754999999999999e-53 23669800.0 110916.0 93981.0 115070.0 92173.0 77168.0 79272.0 64587.3 56299.2 78664.0 50984.4 True False 109334.31750049669 93763.3927686756 105609.38878304545 98951.70990011451 72629.12995812537 75881.72135205749 67931.31436591403 58915.06636233428 69804.03195135674 59796.98560755733 1.8284252356473079 1.5680287528879298 1.766132317708306 1.6547942826002366 1.2145951709804292 1.268989073296486 1.1360324216297728 0.9852514430909441 1.1673503478833334 1.0 15.867785138911957 -6.376278223034558 1.4526881329917516 1.0878532706578137 1.72861081244797 0.8935745805973572 0.09793785628969165 0.12209688203558375 0.5200306592351192 0.037877668049119885 0.04748331686201872 4.204571836705933e-07 6.376278223034558 0.6407575417901563 YQQETSVSQLPGRPKS(ph)PLSK ddPTM_PC-9_AZD4547_30min_R2 3 YQQETSVSQLPGRPKSPLSK 20 2 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 YQQETSVSQLPGRPKS(0.883)PLS(0.117)K;YQQETSVSQLPGRPKS(0.922)PLS(0.078)K;YQQETSVSQLPGRPKS(0.861)PLS(0.139)K 92.679 0.00020065 191548000.0 175784.0 136340.0 221137.0 305836.0 300990.0 236959.0 198586.0 216760.0 224775.0 258341.0 True False 231679.65546566137 180409.23872598534 218204.57889165112 235330.23531909758 259202.73396558504 222141.91627081527 216259.76928794238 183264.722649276 236656.14761274258 249296.5602228802 0.9293335425829035 0.7236731969534314 0.8752811458632573 0.9439770653421925 1.0397365039206652 0.8910749352987957 0.867479956781587 0.7351273619075637 0.9492956798166946 1.0 17.92750345119471 -12.633626823226972 1.230694668241656 3.779205899428186 0.8806231361592837 0.12731286314077284 0.09084626077352172 600411.426290519 9850.50599022708 4658701.154002892 0.02868346738359736 2.324733515103406e-13 12.633626823226972 -2.898582763268902 YQQETSVSQLPGRPKS(ph)PLSK ddPTM_PC-9_Lapatinib_30min_R1 2 YQQETSVSQLPGRPKSPLSK 20 2 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 YQQETSVSQLPGRPKS(0.848)PLS(0.152)K;YQQETSVSQLPGRPKS(0.856)PLS(0.144)K 91.54700000000001 0.00020793 127211000.0 245620.0 184183.0 193984.0 195505.0 210632.0 189700.0 158302.0 158557.0 221687.0 157611.0 True False 242117.41375880796 183756.53557967008 178035.38431989404 209883.08988556085 198243.039878445 181586.9732122986 166498.10298236506 165924.1370607867 196718.27559239863 184853.85134654318 1.309777491759766 0.9940638739259158 0.9631142820288519 1.135400146422136 1.0724312121947694 0.9823272379209443 0.900701293316487 0.8975963219166628 1.0641827268376105 1.0 17.496025576174986 -6.795591655627732 3.889353449118403 0.9555058069451167 1.0854730273174482 0.2885920512226756 0.0981820009574442 0.3042175503737675 9.796335435624053 0.03560058174899912 0.032471330579750206 1.6010627165939606e-07 6.795591655627732 0.12996722037233155 YQQGDFGYCPR ddPTM_PC-9_AZD4547_30min_R2 1 YQQGDFGYCPR 11 0 Q5SRQ6;P67870;Q5SRQ3;N0E472;A0A0G2JM12 Q5SRQ6 CSNK2B;CSNK2B-LY6G5B-1181;CSNK2B-LY6G5B--991 Casein kinase II subunit beta 0 126.71 0.0021319000000000004 0.0 7013.2 8054.8 6567.7 11262.0 9914.5 7909.3 5625.1 11533.0 9771.1 9075.1 False True 9243.251716377925 10658.356579800982 6480.608006741052 8665.719896165512 8538.042811727262 7414.730220674311 6125.7230027373835 9750.839851975 10287.580397903997 8757.383511245465 1.0554809783662609 1.2170708940763475 0.7400164670668155 0.9895329906515745 0.9749536263615103 0.8466832828724428 0.6994923763326416 1.1134421416458267 1.1747321999423215 1.0 13.096284177410668 YQQGDFGYCPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YQQGDFGYCPR 11 0 Q5SRQ6;P67870;Q5SRQ3;N0E472;A0A0G2JM12 Q5SRQ6 CSNK2B;CSNK2B-LY6G5B-1181;CSNK2B-LY6G5B--991 Casein kinase II subunit beta 0 120.63 0.0027344 0.0 9523.3 8696.6 10048.0 9484.8 12504.0 9134.1 9384.8 12661.0 8875.1 6714.9 False True 11135.406596251218 9559.94097417287 10287.58242725221 8953.397406136497 10053.93096071504 8655.09171633594 8495.803803931894 12328.66216543838 9004.881547460389 7932.258214880848 1.40381292370958 1.2051979039510468 1.2969298462766623 1.128732469820511 1.2674739889145255 1.0911258158614987 1.0710447862115533 1.5542436758185603 1.1352229470502244 1.0 12.95351592633181 -2.2455589750353426 1.2541180893434614 1.2025795965758557 143.08244571224068 0.14899204274901157 0.14771444833876418 2289.953548948845 6.596915878197776 0.042054105420669854 932240.3620266111 0.005681212382767995 2.2455589750353426 141.87986611566484 YQQGDFGYCPR ddPTM_PC-9_Lapatinib_30min_R1 2 YQQGDFGYCPR 11 0 Q5SRQ6;P67870;Q5SRQ3;N0E472;A0A0G2JM12 Q5SRQ6 CSNK2B;CSNK2B-LY6G5B-1181;CSNK2B-LY6G5B--991 Casein kinase II subunit beta 0 ; 158.47 1.1710999999999998e-11 0.0 16905.8 13410.8 15686.4 15022.8 17797.9 19691.0 17959.9 15203.599999999999 16433.300000000003 12488.0 False True 16664.720191855988 13379.748116557088 14396.72474325507 16127.626826591706 16751.06251401771 18848.861831962928 18889.77574353438 15910.01475947057 14582.408703679348 14646.534160785955 1.137792737101822 0.9135095012702384 0.982944127614865 1.101122398619816 1.1436878056015691 1.2869161826985742 1.2897096020237409 1.086264817656822 0.9956217999150752 1.0 13.838271696715902 -5.9297356725207 3.519798901879191 1.1520173226827186 1.0021222515022168 0.19136085873323305 0.10769922936569215 0.33345631167009154 8.320340724491881 0.033306739595097404 0.05099061952350797 1.1756128581488365e-06 5.9297356725207 -0.14989507118050183 YQQIT(ph)PVNQSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YQQITPVNQSR 11 0 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 YQQIT(0.894)PVNQS(0.106)R 89.44 0.022693 3903700.0 12588.0 17173.0 21909.0 30678.0 25548.0 24056.0 25241.0 22356.0 18724.0 19669.0 True False 14718.899775667094 18877.82194759683 22431.393650345195 28959.211119417952 20542.05279785254 22794.461011832296 22849.989750985103 21769.17868813999 18997.80307767216 23234.834000281655 0.6334841804976385 0.8124793121985717 0.9654208698057959 1.246370476288615 0.8841058557854782 0.9810468631519372 0.9834367549476839 0.9369199146366228 0.8176431592944399 1.0 14.504001717196626 -4.979994504980453 2.543853152831771 0.9807244806769085 0.6242576918109124 0.5200554014312696 0.10462229195783296 0.28320372689184575 3.1439340303705197 0.028734479096242327 0.18196700094141494 1.0471417971905549e-05 4.979994504980453 -0.35646678886599614 YQQITPVNQS(ph)R ddPTM_PC-9_AZD4547_30min_R2 2 YQQITPVNQSR 11 0 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 YQQITPVNQS(1)R;YQQITPVNQS(1)R 153.81 0.0004614 50572000.0 79043.0 94702.0 116573.0 182502.0 131536.0 152231.0 131739.0 141556.0 110451.0 145823.0 True False 104177.02980346465 125312.5695014543 115027.16585255491 140428.98352779253 113274.49687663108 142711.97150487007 143463.51578774038 119681.7728332759 116289.21436981444 140717.78115506683 0.7403259840251791 0.8905240579608312 0.8174316344982614 0.997947682056214 0.8049764283293093 1.0141715590839633 1.019512350252651 0.8505092380712721 0.8264002844222449 1.0 17.10244511405191 -3.7079351523783215 0.7883421072257919 0.9254042583695103 2.317718254121813e-15 0.30415296729433305 0.08175974413237674 15.79979240162177 2.0918269610402116 0.030065433511075306 19.022958584529363 0.00019591371844811286 3.7079351523783215 -0.925404258369508 YQQITPVNQS(ph)R ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YQQITPVNQSR 11 0 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 YQQIT(0.005)PVNQS(0.995)R;YQQITPVNQS(1)R 107.39 0.0023159 23736000.0 46877.0 48699.0 71259.0 66450.0 58765.0 64051.0 61097.0 53895.0 52914.0 41474.0 True False 54812.35023704686 53533.51487952125 72958.08481126254 62727.02193380672 47250.420098082206 60692.05280465869 55309.44985602541 52480.31335647272 53687.76714654697 48992.907891996656 1.1187813215308424 1.0926788627761026 1.4891560421785204 1.280328615563838 0.9644338768836561 1.2387926215453966 1.1289276802665678 1.071181842730461 1.0958273239241072 1.0 15.580285302459476 -7.599821580450429 0.5893068536151531 1.0150868524519931 1.2257961049321213 0.21412588618292028 0.12866193172947898 1.3450172930049726 0.965364005544055 0.13043480845146965 0.08105385469754371 2.5129185922596805e-08 7.599821580450429 0.21070925248012817 YQQITPVNQS(ph)R ddPTM_PC-9_Lapatinib_30min_R1 5 YQQITPVNQSR 11 0 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 YQQIT(0.012)PVNQS(0.988)R;YQQITPVNQS(1)R;YQQITPVNQS(1)R;YQQITPVNQS(1)R;YQQITPVNQS(1)R 153.81 9.6448e-05 109191300.0 384763.0 306702.0 322534.0 318922.0 296807.0 283856.0 221659.0 234644.0 268024.0 177438.0 True False 379276.20906310645 305991.8503627153 296016.49953724403 342376.5877726036 279349.39580501383 271716.14058065484 233135.41843418358 245546.41685003572 237836.31470215658 208107.92187872686 1.82249770041972 1.470351765566279 1.4224182187055097 1.64518767321179 1.3423294667648564 1.305650155590882 1.1202621040540748 1.1798994225367636 1.1428508465946514 1.0 17.666972358479903 -5.5539011433333565 0.2656358964015904 0.9632801255825469 2.073940297275521 0.8266428910454555 0.10018958743211097 2.563158807743843 0.21402506940199464 0.1502141228783774 0.911609162301955 2.7931795688573513e-06 5.5539011433333565 1.110660171692974 YQSVSS(ph)TPR ddPTM_PC-9_AZD4547_30min_R2 1 YQSVSSTPR 9 0 Q6ZUB1 Q6ZUB1 SPATA31E1 Spermatogenesis-associated protein 31E1 1 YQSVS(0.013)S(0.493)T(0.493)PR 77.192 0.023417 1578200.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 YQT(ph)QPVTLGEVEQVQSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 YQTQPVTLGEVEQVQSGK 18 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 YQT(0.995)QPVT(0.005)LGEVEQVQSGK;YQT(0.594)QPVT(0.406)LGEVEQVQSGK;YQT(0.696)QPVT(0.304)LGEVEQVQSGK;YQT(0.795)QPVT(0.205)LGEVEQVQSGK;YQT(0.81)QPVT(0.19)LGEVEQVQSGK;Y(0.004)QT(0.992)QPVT(0.004)LGEVEQVQSGK 237.09 5.272e-43 166522700.0 248401.0 186856.0 166959.0 217207.0 181440.0 202240.0 196835.0 160073.0 169590.0 140526.0 True False 290450.3831566155 205405.82879171727 170939.93575553346 205037.59598459536 145888.13447793797 191634.17837682753 178189.36383800814 155871.25336136305 172069.93291724083 166002.25139679582 1.7496773731239994 1.2373677288311886 1.0297446830822496 1.2351494889939367 0.8788322643240603 1.1544071045082613 1.0734153443020567 0.9389707190704504 1.0365518025773122 1.0 17.340843282617243 YQT(ph)QPVTLGEVEQVQSGK ddPTM_PC-9_Lapatinib_30min_R1 4 YQTQPVTLGEVEQVQSGK 18 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 YQT(0.98)QPVT(0.02)LGEVEQVQSGK;YQT(0.99)QPVT(0.01)LGEVEQVQSGK;Y(0.001)QT(0.471)QPVT(0.357)LGEVEQVQS(0.171)GK;YQT(0.955)QPVT(0.045)LGEVEQVQSGK 204.47 1.0639000000000002e-19 159630300.0 193477.0 158016.0 155797.0 138030.0 116593.3 144350.0 116888.0 100190.9 124732.1 82057.0 True False 190717.98250066378 157650.1236604741 142987.9720538113 148181.18665458195 109735.5113252473 138176.486996285 122939.88870262365 104846.13497886296 110683.45741075752 96240.4431159204 1.9816822982719062 1.6380860120374396 1.4857368422710202 1.5396976765381223 1.1402224238834007 1.4357424230669136 1.27742438337014 1.0894186641740324 1.1500721923883985 1.0 16.554355664620267 -1.5228787452803376 0.2533755417011445 1.0358548883313141 6.856596799205341 0.8667396234885567 0.10439089011764421 17.27880191153615 0.2361879860558088 0.13192027143152818 43.05395904616152 0.029999999999999995 1.5228787452803376 5.820741910874027 YQTQPVT(ph)LGEVEQVQSGK ddPTM_PC-9_AZD4547_30min_R2 3 YQTQPVTLGEVEQVQSGK 18 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 YQT(0.002)QPVT(0.998)LGEVEQVQSGK;YQT(0.178)QPVT(0.82)LGEVEQVQS(0.002)GK;YQT(0.112)QPVT(0.888)LGEVEQVQSGK 161.1 1.1189e-05 186892300.0 103912.0 81254.0 148341.0 168168.0 122440.0 115331.0 142468.0 109167.0 94637.0 119569.0 True False 136953.85449613066 107517.76649142746 146373.90141571255 129399.46576969996 105441.31946824236 108119.33433813228 155147.37600291352 92297.7485580991 99639.31861473521 115382.92570397134 1.1869507872204776 0.9318342886128327 1.2685923894082236 1.1214784594879292 0.9138381508782734 0.9370479529659815 1.3446302826551877 0.7999255348655311 0.8635534071165067 1.0 16.816070225069204 -7.805558187995287 24.999589911341516 0.8738043953214873 1.087920516490814 0.309423850177556 0.14435872517339784 170.3588320498902 96530.31352769087 0.07818407367257106 0.03755871788689367 1.564738657096585e-08 7.805558187995287 0.21411612116932655 YQTQPVT(ph)LGEVEQVQSGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YQTQPVTLGEVEQVQSGK 18 0 O95425-2;O95425-4;O95425-3;A0A6I8PIX7;O95425 O95425-2 SVIL Supervillin 1 YQT(0.023)QPVT(0.977)LGEVEQVQSGK 129.43 0.00010256 4470900.0 27050.0 25168.0 20993.0 19238.0 18293.0 23222.0 21453.0 25843.0 22302.0 13716.0 True False 31629.030738147016 27666.51271048258 21493.552736395843 18160.15723043752 14708.617967399268 22004.197440005362 19420.816533730165 25164.64863292189 22628.124558761207 16202.602224203732 1.9520957374920316 1.7075351432841976 1.326549429466854 1.1208173217577084 0.9077935608039106 1.3580656449823292 1.1986232992080128 1.5531238923665296 1.3965734791019504 1.0 13.983937915774431 -5.1510642543857115 2.3698420489085006 1.232968347723328 1.9402851399033567 0.6528540657366015 0.1794698483024353 0.22074787714880906 2.238677584013815 0.05257410576425761 0.2272815034913272 7.062130614699045e-06 5.1510642543857115 0.7073167921800287 YQVS(ph)DGSLTVTSVSR ddPTM_PC-9_AZD4547_30min_R2 1 YQVSDGSLTVTSVSR 15 0 H0YDP1;Q9UPX0;Q9UPX0-2 H0YDP1 IGSF9B Protein turtle homolog B 1 YQVS(0.608)DGS(0.319)LT(0.063)VT(0.008)S(0.002)VSR 104.55 0.0011394 67111000.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 YQVS(ph)DGSLTVTSVSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YQVSDGSLTVTSVSR 15 0 H0YDP1;Q9UPX0;Q9UPX0-2 H0YDP1 IGSF9B Protein turtle homolog B 1 YQVS(0.481)DGS(0.481)LT(0.036)VT(0.003)SVSR 130.47 1.2242e-05 40660000.0 0.0 0.0 2205.7 0.0 0.0 2893.7 2777.8 2324.4 0.0 0.0 True False 0.0 0.0 2258.292253163832 0.0 0.0 2741.9492779322873 2514.6666744695704 2263.3869629053747 0.0 0.0 0.0 YQVSDGS(ph)LTVTSVSR ddPTM_PC-9_AZD4547_30min_R2 1 YQVSDGSLTVTSVSR 15 0 H0YDP1;Q9UPX0;Q9UPX0-2 H0YDP1 IGSF9B Protein turtle homolog B 1 YQVS(0.199)DGS(0.765)LT(0.028)VT(0.008)SVSR 127.03 2.1944000000000002e-05 60863000.0 0.0 0.0 0.0 3107.4 0.0 0.0 3006.7 0.0 0.0 2610.6 True False 0.0 0.0 0.0 2391.036938851421 0.0 0.0 3274.290475250304 0.0 0.0 2519.203688604797 0.0 0.0 0.0 0.9491241020592668 0.0 0.0 1.2997323281404427 0.0 0.0 1.0 11.298752059636088 -14.522878745274683 0.13228682173406228 3.1969632866785784 8.509962614402504e-11 0.19408477685039527 0.45196239062242527 264.1284295836447 2.1819494443744496 157.68356083414093 3.3504757460663295 3.0000000000390587e-15 14.522878745274683 -3.196963286593479 YQVSDGSLT(ph)VTSVSR ddPTM_PC-9_Lapatinib_30min_R1 1 YQVSDGSLTVTSVSR 15 0 H0YDP1;Q9UPX0;Q9UPX0-2 H0YDP1 IGSF9B Protein turtle homolog B 1 YQVS(0.215)DGS(0.215)LT(0.434)VT(0.136)SVSR 98.25299999999999 0.0056042999999999996 36105000.0 1777.8 0.0 1345.2 0.0 0.0 2363.4 0.0 1406.8 1512.1 2050.7 True False 1752.4482459914088 0.0 1234.602848622164 0.0 0.0 2262.3228913544867 0.0 1472.1650637758946 1341.791374881097 2405.1607626140108 0.7286200046298728 0.0 0.5133140652437533 0.0 0.0 0.9406119235438204 0.0 0.6120859306618222 0.5578801200061123 1.0 11.231917612617734 -8.66122325409492 0.7243249204203112 1.0044328523725041 0.28891889774041424 0.28587936023157434 0.3240626792486862 1.09245497749945 1.2417106545789458 0.3098966073036854 0.11670558916190751 2.181608142673195e-09 8.66122325409492 -0.7155139546320899 YQYGGLNS(ph)GRPVTPPR ddPTM_PC-9_AZD4547_30min_R2 1 YQYGGLNSGRPVTPPR 16 1 P62140 P62140 PPP1CB Serine/threonine-protein phosphatase PP1-beta catalytic subunit 1 Y(0.001)QY(0.016)GGLNS(0.921)GRPVT(0.062)PPR 81.525 0.034473000000000004 30240000.0 18745.0 19933.0 29703.0 31731.0 27668.0 34380.0 24714.0 35904.0 27206.0 27989.0 True False 24705.520079778722 26375.952438939887 29309.118812404588 24415.908189063044 23826.77578444399 32230.213165107234 26913.498122638088 30355.86179184174 28644.0536178502 27009.11362918857 0.9147105091623455 0.9765574983710524 1.0851566332310296 0.9039877622150818 0.8821754061079055 1.1933088070789653 0.996459879881169 1.1239118102356518 1.0605329005278707 1.0 14.721158674570091 -6.7495460132569685 24.99981079846958 1.0776882601728226 0.9585258651322777 0.40114187766482523 0.07450951453075816 240.89078372643544 506350.60509741737 0.024619277166175946 0.024433565869868775 1.780139294101515e-07 6.7495460132569685 -0.11916239504054493 YQYGGLNSGRPVT(ph)PPR ddPTM_PC-9_AZD4547_30min_R2 2 YQYGGLNSGRPVTPPR 16 1 P62140 P62140 PPP1CB Serine/threonine-protein phosphatase PP1-beta catalytic subunit 1 YQYGGLNS(0.001)GRPVT(0.999)PPR;YQYGGLNS(0.003)GRPVT(0.997)PPR 62.357 0.027225 268492000.0 75993.0 86695.0 115475.0 121551.0 111723.0 105701.0 99917.0 146574.0 92620.0 121775.0 True False 100157.19324740593 114717.46333687333 113943.72604997542 93529.2948942296 96212.18992935674 99091.49976047117 108809.41943512298 123924.35623544487 97515.70411252238 117511.69431542521 0.8523168168996331 0.9762216773842814 0.9696373345118092 0.7959147848143353 0.8187456617815732 0.8432479876810345 0.9259454564841559 1.054570414947867 0.8298382955041943 1.0 16.842444809876937 -10.679116328730437 6.692416807959133 1.0000002266104093 0.8995176061078848 0.13201273066573238 0.0794022279427473 2.837494007618123e-07 3.572675258122277e-08 0.08124344472386134 0.019704385163196957 2.093551608705104e-11 10.679116328730437 -0.10048262050252454 YQYGGLNSGRPVT(ph)PPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YQYGGLNSGRPVTPPR 16 1 P62140 P62140 PPP1CB Serine/threonine-protein phosphatase PP1-beta catalytic subunit 1 YQYGGLNSGRPVT(1)PPR;YQYGGLNSGRPVT(1)PPR;YQYGGLNS(0.004)GRPVT(0.996)PPR;YQYGGLNS(0.001)GRPVT(0.999)PPR 75.316 0.008955 460462000.0 182750.0 175066.0 191953.0 194062.0 218491.0 192580.0 197036.0 171899.0 173824.0 133334.0 True False 213685.96552297135 192445.3955091127 196529.8875058065 183189.3352974925 175679.25700076667 182480.76578228569 178371.32366289332 167386.83339204587 176365.84715729996 157506.39872863676 1.3566811713543445 1.2218258881067514 1.2477581170807046 1.1630596393299815 1.115378539658185 1.1585609680320132 1.1324703320161877 1.0627303699605997 1.119737665141818 1.0 17.265050914011624 -1.5228787452803376 0.19971795658390298 1.0183509575674097 2.4972330150949826 0.8687572962909798 0.03429242444137561 17.771353075391158 0.2145232432671114 0.061976583545252865 8.220246643678607 0.029999999999999995 1.5228787452803376 1.478882057527573 YQYGGLNSGRPVT(ph)PPR ddPTM_PC-9_Lapatinib_30min_R1 3 YQYGGLNSGRPVTPPR 16 1 P62140 P62140 PPP1CB Serine/threonine-protein phosphatase PP1-beta catalytic subunit 1 YQYGGLNS(0.036)GRPVT(0.964)PPR;YQYGGLNS(0.001)GRPVT(0.999)PPR;YQYGGLNSGRPVT(1)PPR 130.47 0.00014076 159866000.0 144250.0 172208.0 185097.0 151321.0 165423.0 153751.0 157624.0 179070.0 180417.0 137957.0 True False 142192.96854778958 171809.26295642776 169879.03915508225 162449.6511320585 155693.14437413125 147175.42814108633 165784.99945984487 187390.24592717463 160096.53758476477 161802.683633852 0.8788047599356399 1.0618443347034956 1.0499148428187166 1.0039984967101692 0.9622408039068981 0.9095981898182474 1.024612174140477 1.15814053091496 0.9894553909071859 1.0 17.30387601071609 -7.521615496897817 24.997512136000193 1.0625540452453173 0.9838088771596956 0.17682014729070206 0.06801369177320137 78.30564973780349 1549634.389721821 0.03153762523063152 0.018521202365719008 3.0087389141225054e-08 7.521615496897817 -0.07874516808562171 YRCT(ph)DCDY(ph)T(ph)T(ph)NK ddPTM_PC-9_AZD4547_30min_R2 1 YRCTDCDYTTNK 12 1 E9PEP7;P17010-2;P17010;P17010-3 E9PEP7 ZFX Zinc finger X-chromosomal protein 4 Y(0.013)RCT(0.998)DCDY(0.993)T(0.996)T(0.999)NK 41.092 0.045774 0.0 0.0 0.0 571.72 997.87 445.34 890.32 884.58 544.74 0.0 533.36 True False 0.0 0.0 564.1386192447881 767.8264884378158 383.51222812795595 834.648149655564 963.3059063414755 460.5629498798984 0.0 514.6872287421495 0.0 0.0 1.0960804693434758 1.491831243441413 0.7451364765067636 1.621660890431206 1.8716335913282922 0.894840447091477 0.0 1.0 9.00755217426407 -5.2664188476754745 6.893299088499485 1.1367802837937562 2.7233475800358857e-11 0.4373726292367679 0.4924245155070411 0.1161796025791365 36.63951446345526 0.1347216035127817 0.3130582545675546 5.414784191592193e-06 5.2664188476754745 -1.1367802837665226 YRDCLTESNLIK ddPTM_PC-9_Lapatinib_30min_R1 1 YRDCLTESNLIK 12 1 P21980 P21980 TGM2 Protein-glutamine gamma-glutamyltransferase 2 0 67.952 0.046235000000000005 6371100.0 78591.0 73384.0 61125.0 65376.0 79404.0 63971.0 63902.0 65653.0 72077.0 63178.0 False True 77470.27792817555 73214.08385669948 56099.53844932334 70183.96912794284 74733.61283427046 61235.10945368448 67210.53288511276 68703.47805806011 63958.92925554186 74098.2331206066 1.0455077626760736 0.9880678765650454 0.7570968441043995 0.9471746649303677 1.0085748294784531 0.8264044481872416 0.9070463633824707 0.9271945519434225 0.863164026481422 1.0 16.177151521290682 -5.012205679371642 24.46553710385315 0.902384223092679 1.031147884467582 0.2926923973152603 0.07216268776036981 476.5278211993169 955189.3050806272 0.017785977405198394 0.05363251173699029 9.72286645352396e-06 5.012205679371642 0.12876366137490314 YREPPPT(ph)PPGYLGISLADLK ddPTM_PC-9_AZD4547_30min_R2 2 YREPPPTPPGYLGISLADLK 20 1 E9PCH4;Q8TEU7;A0A5F9ZHG7;Q8TEU7-4 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 1 Y(0.008)REPPPT(0.991)PPGYLGISLADLK;Y(0.167)REPPPT(0.833)PPGYLGISLADLK 92.133 0.00046035 12130200.0 43880.0 44856.0 54387.0 78105.0 63972.0 52329.0 46558.0 68607.0 58259.0 61981.0 True False 57832.92723930062 59354.82479311132 53665.79284416547 60099.09896022091 55090.592037098846 49056.85935767585 50701.57180520291 58005.36458202107 61338.4518018942 59811.06405554815 0.9669269081317399 0.9923719922117903 0.8972552769555245 1.0048157462038336 0.9210769429872494 0.8201970677551468 0.8476955326879821 0.9698099423235461 1.0255368763365842 1.0 15.868124763331062 -7.995809559128217 24.90474406790056 1.007736780553469 0.9215800275919782 0.3073175579796449 0.05540947354540321 146.4611584542687 870452.8218295571 0.033902493418795 0.01618169863800319 1.0096955468857882e-08 7.995809559128217 -0.08615675296149072 YREPPPT(ph)PPGYLGISLADLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YREPPPTPPGYLGISLADLK 20 1 E9PCH4;Q8TEU7;A0A5F9ZHG7;Q8TEU7-4 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 1 Y(0.097)REPPPT(0.901)PPGY(0.002)LGIS(0.001)LADLK;Y(0.139)REPPPT(0.86)PPGY(0.001)LGISLADLK 57.00899999999999 0.014247999999999999 22102200.0 42241.2 40738.0 41902.0 53878.0 64010.0 70093.0 67581.0 83314.0 71891.0 62468.0 True False 49391.80085827048 44782.19941193732 42901.10259421993 50859.39033483277 51467.69999962972 66417.19968832559 61179.23843593059 81127.09577847966 72942.26987059032 73792.95390358398 0.6693294988950377 0.6068628106478651 0.5813712600565283 0.689217433974582 0.6974608994088531 0.9000479879841188 0.8290661262302338 1.0993881053261303 0.9884720154433017 1.0 16.17119544714054 -6.955691280905414 0.9717982894195117 1.029473452546358 0.6157838235310051 0.8772166406671638 0.06075220528601866 0.16601180869509505 0.3273796622372959 0.037589841443748426 0.02829242884038143 1.1074107093518784e-07 6.955691280905414 -0.4136896290153529 YREYS(ph)PPYAPSHQQYPPSHATPLPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YREYSPPYAPSHQQYPPSHATPLPK 25 1 Q9UPT8 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 Y(0.167)REY(0.051)S(0.537)PPY(0.015)APS(0.223)HQQY(0.006)PPSHATPLPK;Y(0.029)REY(0.029)S(0.703)PPY(0.029)APS(0.199)HQQY(0.009)PPS(0.003)HAT(0.001)PLPK 51.9 0.007288899999999999 14166400.0 21133.0 29899.0 58685.0 60545.0 79922.0 69700.0 62655.0 62175.0 63753.0 47242.0 True False 24710.399504224068 32867.17512439281 60084.27296410189 57152.85993953842 64261.85782487748 66044.80930016257 56719.86481708218 60542.972129857924 64685.267016173566 55806.600632533795 0.44278632319737726 0.588947808177947 1.07665172727031 1.0241236572689538 1.151509984419558 1.1834587405716335 1.0163648058508687 1.0848711701418872 1.159097065275532 1.0 15.768148149214007 -5.1963481323285725 3.0001300685290544 1.0956409785449157 0.45913631161153484 0.9341460430102639 0.06115400944661835 0.058118760567217265 1.0091983702500191 0.016418847159267655 0.05457698853041537 6.362852674116889e-06 5.1963481323285725 -0.6365046669333809 down YREYS(ph)PPYAPSHQQYPPSHATPLPK ddPTM_PC-9_Lapatinib_30min_R1 1 YREYSPPYAPSHQQYPPSHATPLPK 25 1 Q9UPT8 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 Y(0.07)REY(0.074)S(0.607)PPY(0.082)APS(0.154)HQQY(0.013)PPS(0.001)HAT(0.001)PLPK 41.208999999999996 0.036722000000000005 10756000.0 37700.0 18383.0 53891.0 26597.0 51309.0 48081.0 32853.0 33269.0 65609.0 30077.0 True False 37162.39108666672 18340.43529294815 49460.29000527584 28553.032104991064 48291.10549737521 46024.687712285326 34553.967589036416 34814.799194455656 58219.42352660126 35275.76937491669 1.0534820854422395 0.5199159541503683 1.4021037919713029 0.8094233693821029 1.3689596670204238 1.3047110956851817 0.9795383120291766 0.9869323847890669 1.6504083272525012 1.0 15.10638992831876 -5.265166476044183 24.977327990435654 1.176992699088354 0.7866990255967362 0.26483127781344884 0.2668055423935653 380.92931408346226 2552834.998388887 0.06610447163299737 0.14679028701453634 5.430421298261586e-06 5.265166476044183 -0.3902936734916177 YREYSPPYAPS(ph)HQQYPPSHATPLPK ddPTM_PC-9_AZD4547_30min_R2 1 YREYSPPYAPSHQQYPPSHATPLPK 25 1 Q9UPT8 Q9UPT8 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 Y(0.014)REY(0.045)S(0.05)PPY(0.03)APS(0.839)HQQY(0.018)PPS(0.002)HAT(0.002)PLPK 51.431000000000004 0.0068076000000000005 13008000.0 16048.0 15543.0 48664.0 81836.0 65871.0 54748.0 29827.0 52768.0 30162.0 50450.0 True False 21150.930180863652 20566.970790068866 48018.68356350726 62969.974553596316 56725.94866622491 51324.598905273124 32481.54521744464 44613.918088009836 31756.301743056578 48683.760855784865 0.43445555168834876 0.42246059935661257 0.986338826734283 1.2934492620677205 1.1651924105506821 1.054244742046761 0.6671946588856232 0.9164024574882154 0.6522976283021308 1.0 15.571153001142847 -5.261101295947303 24.787461029102865 0.9750658498964072 0.42845801910509074 0.5717657324185368 0.18628245473144686 19.535848320647187 1432156.728081422 0.053615035003064596 0.12514050037279864 5.481490983224412e-06 5.261101295947303 -0.5466078307913165 YRGDYDR ddPTM_PC-9_AZD4547_30min_R2 1 YRGDYDR 7 1 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 0 84.916 0.025452000000000002 24855000.0 31945.0 22167.0 43543.0 47982.0 44642.0 34680.0 26593.0 42638.0 37654.0 40219.0 False True 42102.84550272239 29332.04925068884 42965.59136950922 36920.4912145102 38444.22887701129 32511.45411768235 28959.72548253278 36049.27682376747 39644.31356783545 38810.94505171086 1.0848188686625762 0.7557674571337403 1.107048316196959 0.9512907033136693 0.9905512175956815 0.8376877727240291 0.7461741898824538 0.9288430564042228 1.0214725128443594 1.0 15.244175942918025 -6.744659088934143 24.967091700719376 0.8923468555248693 0.9712520196334983 0.07892855929994724 0.11510484646105319 599.5323293704329 892031.8356217963 0.03784782860546728 0.03775190486070988 1.8002835413191428e-07 6.744659088934143 0.07890516410862902 YRGDYDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YRGDYDR 7 1 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 0 77.923 0.037701 23205000.0 18527.0 14686.0 23593.0 19817.0 25642.0 19924.0 22010.0 20606.0 17007.0 17870.0 False True 21663.255175070244 16143.92902360724 24155.546596950757 18706.71773758085 20617.634172637187 18879.15036580257 19925.0534613994 20065.11433386171 17255.69520091703 21109.689541157826 1.0262232958392459 0.7647639247432426 1.1442871554247345 0.8861673546220624 0.9766905445216865 0.8943357659994787 0.9438818805246412 0.9505167896827903 0.8174300795505962 1.0 14.36561774076765 -6.757983181668035 24.96448266893541 0.9195557655313455 0.954978622006024 0.03394965202177591 0.1006920459067478 413.5768929419571 2987312.3064829335 0.03218364314792248 0.030960548968529587 1.7458897623106264e-07 6.757983181668035 0.035422856474678466 YRNEGS(ph)PSPR ddPTM_PC-9_Lapatinib_30min_R1 2 YRNEGSPSPR 10 1 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 Y(0.001)RNEGS(0.997)PS(0.003)PR;YRNEGS(0.997)PS(0.002)PR 77.279 0.010373 20455900.0 53348.0 56102.0 60717.0 56189.0 58699.0 63454.0 56716.0 54697.0 62209.0 53416.0 True False 52587.24773717495 55972.09926589661 55725.082634397826 60321.32650100919 55246.440226674196 60740.22033849861 59652.47696648068 57238.42230121561 55202.36733018856 62648.88442765399 0.8393963949653713 0.8934253143889955 0.8894824408046457 0.9628475758521666 0.881842362100988 0.9695339493018511 0.9521714155240304 0.9136383324959871 0.8811388715777603 1.0 15.935001199630973 -3.872881923719442 0.6943144172060168 0.9351675873001768 0.5747580699777909 0.40251890909438026 0.03693980376002954 9.824436829020486 1.4087775649440923 0.01466940578068953 3.7261531625036115 0.00013400409691576528 3.872881923719442 -0.3604095173223859 YRPGTVALR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YRPGTVALR 9 1 K7EMV3;A0A590UJJ6;B4DEB1;K7EK07;K7ES00;P84243;K7EP01;Q71DI3;Q16695;P68431;Q5TEC6;Q6NXT2 K7EMV3 H3F3B;H3F3A;HIST2H3A;HIST3H3;HIST1H3A;HIST2H3PS2;H3F3C Histone H3;Histone H3.3;Histone H3.2;Histone H3.1t;Histone H3.1;Histone H3.3C 0 120.31 0.0021842 8988600.0 29243.0 54414.0 35439.0 52550.0 63202.0 52184.0 58806.0 52825.0 40428.0 40648.0 False True 34193.2623244227 59815.862310402044 36284.000163155935 49605.79386939868 50818.02179935321 49447.37917531823 53235.46996142901 51438.39972271404 41019.18301773822 48017.16063060906 0.7121050448498579 1.245718437426135 0.755646516508648 1.0330846975940706 1.0583304204571962 1.0297855709485133 1.108675924654601 1.0712503414857077 0.8542609033735763 1.0 15.551262475636511 -5.905129937073965 21.32193106499153 1.0306644961980278 0.9312345791643759 0.10803616041607511 0.14775587326482356 13.585655469123871 3037.086052949671 0.03921311906139572 0.05816263467864855 1.244142319685211e-06 5.905129937073965 -0.0994299170336519 YRQDDDQR ddPTM_PC-9_AZD4547_30min_R2 1 YRQDDDQR 8 1 Q7KZF4;H7C597 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 90.709 0.022890999999999998 0.0 11952.0 10438.0 8642.3 6198.5 9017.3 7524.4 4552.5 7273.5 13586.0 14838.0 False True 15752.487382956275 13811.879373784916 8527.697455221496 4769.531590870353 7765.403544927961 7053.898078520442 4957.663680638909 6149.547703402428 14304.128223631282 14318.526136335695 1.1001472660640441 0.9646159976434252 0.5955708970339492 0.3331021325419001 0.542332602600901 0.49264135228415556 0.3462412006259495 0.4294818925389887 0.998994455674605 1.0 13.805595377372859 -5.214214821765381 3.3380676496986124 0.5453214109548999 1.0702256065704552 0.36934466339683536 0.22704055957694452 0.22632154937982382 5.077641012058728 0.05830949669538132 0.17806206992531487 6.106398999750872e-06 5.214214821765381 0.5249041956155552 YRQDDDQR ddPTM_PC-9_LapatinibAZD4547_30min_R1 6 YRQDDDQR 8 1 Q7KZF4;H7C597 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 ;;;;; 107.69 0.0049335 23960800.0 34637.1 64482.9 54760.7 44760.200000000004 105420.3 93674.59999999999 49403.4 86885.8 100786.7 109495.7 False True 40500.47691609141 70884.33615936014 56066.402769111206 42252.43110852633 84763.94898095554 88762.13907129127 44723.552302357966 84605.13981311467 102260.51481779627 129346.40364251588 0.31311637413611854 0.5480193817778527 0.4334593091901188 0.32666104289457065 0.6553251315376643 0.6862358486333311 0.34576571936212247 0.6540973496792697 0.790594186912387 1.0 16.98088041621179 -8.905186546616887 0.27672693181694846 1.1260391505852463 0.37127554961118325 0.6548940104390213 0.12541242589180016 2.249418221899038 0.41074733667578506 0.5412750799810351 0.22079561183483076 1.2439801584307035e-09 8.905186546616887 -0.754763600974063 YRQDDDQR ddPTM_PC-9_Lapatinib_30min_R1 4 YRQDDDQR 8 1 Q7KZF4;H7C597 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 ;;; 116.37 0.0046576000000000005 25180000.0 10937.6 17776.1 14948.2 16490.0 20800.3 10944.45 24517.5 26058.800000000003 23388.6 16948.899999999998 False True 10781.627818289811 17734.94053261033 13719.21669772067 17702.729609027425 19576.86724896322 10476.38138625904 25786.896184951165 27269.58698032648 20754.32957512335 19878.49478201034 0.5423764694722751 0.892167174984502 0.6901536986661737 0.890546784510468 0.9848264400119425 0.527020858527979 1.297225794394041 1.3718134737749328 1.044059412079109 1.0 14.278920898384069 -7.27482520565657 24.97084994107134 1.2092591512611475 0.7744985590450688 0.5868393257512821 0.172925795139511 537.9318441033324 1003491.5804184963 0.06997220922817045 0.047480035731002554 5.3109815699588044e-08 7.27482520565657 -0.43476059221607866 YRS(ph)DIHTEAVQAALAK ddPTM_PC-9_AZD4547_30min_R2 2 YRSDIHTEAVQAALAK 16 1 Q9P265 Q9P265 DIP2B Disco-interacting protein 2 homolog B 1 Y(0.43)RS(0.57)DIHTEAVQAALAK;Y(0.056)RS(0.885)DIHT(0.06)EAVQAALAK 98.676 0.00095213 19581400.0 172494.0 195719.0 222063.0 292723.0 235019.0 182218.0 169743.0 189876.0 168446.0 171554.0 True False 227343.50390191283 258981.33925635272 219118.29952661344 225240.23487526682 202390.66857323403 170823.87965443594 184849.7981642374 160535.02711641407 177349.7116706753 165547.94667697386 1.3732789108252597 1.5643887130880043 1.3235941847963173 1.3605740173556353 1.2225501592487262 1.0318695162541445 1.1165937232971326 0.9697192284097532 1.071289105244716 1.0 17.336889591258597 -6.3653831515769665 1.0687887812267927 1.0220598574923754 1.4573594345902032 0.8698862488217671 0.06739428022396819 0.15794716135279327 0.3804659400077778 0.0291654640886313 0.03964723346107761 4.311385417078659e-07 6.3653831515769665 0.43529957709782785 YRS(ph)DIHTEAVQAALAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YRSDIHTEAVQAALAK 16 1 Q9P265 Q9P265 DIP2B Disco-interacting protein 2 homolog B 1 Y(0.125)RS(0.863)DIHT(0.012)EAVQAALAK;Y(0.376)RS(0.622)DIHT(0.002)EAVQAALAK 135.43 4.851699999999999e-07 7572300.0 102768.0 111559.0 102728.0 125593.0 138068.0 126022.0 123136.0 129172.0 97870.0 86650.0 True False 120164.59263947839 122633.84025225372 105177.42511810933 118556.43138799953 111014.56652943097 119413.18447094827 111471.66665256165 125781.37186904714 99301.16359815055 102358.95907897723 1.1739528588480745 1.198076273495835 1.0275351182201593 1.1582418623124606 1.0845613078555765 1.1666119462861329 1.0890269660377585 1.2288262112161363 0.9701267430976181 1.0 16.64327785577369 -8.280917771982903 24.965018255812087 0.985063317352373 1.1368183710174071 0.5447250430829114 0.05687479892439518 683.1916786172363 875622.8472346478 0.051969727776177206 0.013498547308295018 5.23699582910698e-09 8.280917771982903 0.15175505366503417 YRS(ph)DIHTEAVQAALAK ddPTM_PC-9_Lapatinib_30min_R1 2 YRSDIHTEAVQAALAK 16 1 Q9P265 Q9P265 DIP2B Disco-interacting protein 2 homolog B 1 Y(0.412)RS(0.588)DIHTEAVQAALAK;Y(0.431)RS(0.546)DIHT(0.023)EAVQAALAK 116.58 7.4045e-05 19640800.0 128580.0 115817.0 131216.0 83312.0 110060.0 99941.0 107229.0 120624.0 100668.0 79104.0 True False 126746.425621316 115548.83285227523 120427.92698840763 89439.04240068469 103586.48718628548 95666.75640384977 112780.7929444734 126228.63139956158 89329.7097589646 92777.02100054541 1.366140281876165 1.245446680720606 1.2980361482796443 0.9640214940740434 1.1165101667327357 1.0311471027215604 1.215611276673891 1.3605592207882975 0.9628430488023478 1.0 16.501479902642366 -5.722977954818473 24.18970196712244 1.1114960471750817 1.2974321332956285 0.3870320015602464 0.11960561941990996 138.22094046011853 86930.37178927027 0.03310577732842 0.05733909037517765 1.8924396781602074e-06 5.722977954818473 0.1859360861205468 YRS(ph)PEPDPYLSYR ddPTM_PC-9_AZD4547_30min_R2 3 YRSPEPDPYLSYR 13 1 H3BUL5;H3BVF8;H3BQG1;P49761-3;P49761-1;P49761;H3BRT8;H3BQR7;H3BV35;H3BRK0;P49761-2 H3BUL5 CLK3 Dual specificity protein kinase CLK3 1 Y(0.221)RS(0.779)PEPDPYLSYR;Y(0.436)RS(0.564)PEPDPYLSYR;YRS(1)PEPDPYLSYR 145.49 0.00044527 58966000.0 148038.0 165055.0 223848.0 256636.0 208813.0 208904.0 181757.0 218763.0 181367.0 219053.0 True False 195111.00461831328 218405.80092355493 220879.62926031492 197472.53518667512 179822.91932474697 195841.19985583387 197933.02089003506 184958.20502363754 190953.68935193098 211384.02114454441 0.9230168087534694 1.0332181199931334 1.044921125373414 0.934188564099854 0.850693057834225 0.9264711627465807 0.936366996040294 0.8749866902057043 0.9033496870672019 1.0 17.68950679965885 -5.9224611711607755 6.336697675386322 0.9090887195159295 1.0028464633774026 0.38284871117768293 0.047971269561865676 0.19021832557094143 12.28625950005508 0.013221167603256005 0.019751273388940088 1.1954704039672186e-06 5.9224611711607755 0.09375774386147306 YRS(ph)PEPDPYLSYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YRSPEPDPYLSYR 13 1 H3BUL5;H3BVF8;H3BQG1;P49761-3;P49761-1;P49761;H3BRT8;H3BQR7;H3BV35;H3BRK0;P49761-2 H3BUL5 CLK3 Dual specificity protein kinase CLK3 1 Y(0.44)RS(0.56)PEPDPYLSYR;Y(0.437)RS(0.563)PEPDPYLSYR 70.438 0.013309 57195000.0 39851.0 47017.0 59687.0 58099.0 63420.0 56209.0 54216.0 55295.0 46109.0 41660.0 True False 46596.98720687236 51684.537035471985 61110.164444208014 54843.90138949943 50993.30626427931 53261.3010897107 49080.26799015127 53843.564839895334 46783.25689534215 49212.62821962148 0.9468502067990296 1.05022915672821 1.2417577897179426 1.1144274015349724 1.0361833559612217 1.0822689829127026 0.9973104417654849 1.0941005751533397 0.9506352045772122 1.0 15.586740945766808 -7.600404478008254 0.8923070361872663 0.9926569554136535 1.0884530092264677 0.15946877916606594 0.07663388358351662 1.1723000897209708 1.7151342294565297 0.06999366581703147 0.0323897211062539 2.5095480876315222e-08 7.600404478008254 0.0957960538128142 YRS(ph)PEPDPYLSYR ddPTM_PC-9_Lapatinib_30min_R1 3 YRSPEPDPYLSYR 13 1 H3BUL5;H3BVF8;H3BQG1;P49761-3;P49761-1;P49761;H3BRT8;H3BQR7;H3BV35;H3BRK0;P49761-2 H3BUL5 CLK3 Dual specificity protein kinase CLK3 1 Y(0.113)RS(0.887)PEPDPYLSYR;Y(0.416)RS(0.584)PEPDPYLSYR;Y(0.001)RS(0.999)PEPDPYLSYR 137.81 0.00029586 104053000.0 83890.0 73357.0 79118.0 70449.0 79928.0 75219.0 60206.0 72382.0 81209.0 56328.0 True False 82693.713216458 73187.14637354056 72613.22344431201 75630.05447097457 75226.79218449413 72002.05871405319 63323.1720897795 75745.13196348224 72062.38725131877 66064.2197476579 1.2517170948558678 1.107818220711449 1.0991308717739952 1.144795999405651 1.1386919042082695 1.0898798016396127 0.9585093463852561 1.1465379028587943 1.0907929818375477 1.0 16.01158150198232 -6.871137351753932 4.103955532436007 1.0569205531447505 1.1433104329404353 0.36679699382590825 0.06105906170591703 0.28702413177646674 8.79325681435358 0.022395451119404015 0.019747547000306048 1.3454347740422543e-07 6.871137351753932 0.0863898797956848 YRS(ph)PYSGPK ddPTM_PC-9_AZD4547_30min_R2 2 YRSPYSGPK 9 1 G3XAC6;Q14498-2;Q14498;Q5QP23;Q5QP22 G3XAC6 RBM39 RNA-binding protein 39 1 Y(0.006)RS(0.994)PYSGPK;YRS(0.993)PYS(0.007)GPK 95.477 0.026128 1820210000.0 100246.0 105985.0 139499.0 196326.0 146003.0 149306.0 131565.0 151878.0 122796.0 126353.0 True False 132122.1427536676 140242.57860036334 137649.15211297254 151066.0739064633 125733.00364522844 139969.8722172631 143274.03012482327 128408.7449092396 129286.74586699746 121929.41992885976 1.0835952703683396 1.1501947494065703 1.1289248500754332 1.238963278875627 1.0311949627791874 1.1479581572595778 1.1750570962153115 1.053139963957511 1.0603408590185237 1.0 16.895686745304502 -7.861095897517002 6.150365296431286 1.0393020741655716 1.1369431217914912 0.421100943464228 0.05320065946137269 0.2140736130748497 11.128819015409379 0.029056587268820454 0.013779773332438577 1.3769053978232927e-08 7.861095897517002 0.09764104762591952 YRS(ph)PYSGPK ddPTM_PC-9_Lapatinib_30min_R1 3 YRSPYSGPK 9 1 G3XAC6;Q14498-2;Q14498;Q5QP23;Q5QP22 G3XAC6 RBM39 RNA-binding protein 39 1 Y(0.005)RS(0.993)PYS(0.001)GPK;Y(0.033)RS(0.967)PYSGPK;Y(0.001)RS(0.98)PYS(0.019)GPK 118.77 0.008581100000000001 1062488000.0 222128.0 178991.0 205378.0 172709.0 169943.0 170053.0 154683.0 166923.0 181725.0 133995.0 True False 218960.41398671368 178576.5573366746 188492.6136220059 185410.5960003349 159947.28686079333 162780.22960290435 162691.72887026818 174678.85196237074 161257.21685091412 157155.85721288543 1.3932691906615162 1.136302270266468 1.199399226760421 1.1797880097410256 1.0177621737898486 1.0357884999628113 1.0352253600696777 1.1115007423856207 1.0260974023543579 1.0 17.26183651694899 -1.5228787452900348 0.4371192058659887 1.0350200715761662 7.758686499660393 0.7808181996022966 0.05387412101206295 40.28877908459873 0.49904763788246714 0.03566833093793879 239.73496229522235 0.029999999999330142 1.5228787452900348 6.723666428084227 YRS(ph)QSGEDESMNQPGPIK ddPTM_PC-9_AZD4547_30min_R2 1 YRSQSGEDESMNQPGPIK 18 1 A0A0C4DG33;O43933-2;O43933 A0A0C4DG33 PEX1 Peroxisome biogenesis factor 1 1 Y(0.008)RS(0.495)QS(0.495)GEDES(0.002)MNQPGPIK 61.222 0.035762 0.0 17579.0 17305.0 21244.0 32328.0 19950.0 24497.0 19505.0 24019.0 22435.0 19822.0 True False 23168.756334085363 22898.502832280872 20962.29067941699 24875.279062621106 17180.28686206656 22965.198717441308 21240.907213808216 20307.415451711404 23620.868298039728 19128.037813347237 1.2112458455053126 1.1971171876449693 1.0958934148901485 1.300461621069336 0.8981729871988455 1.200604000344278 1.1104592860532017 1.0616570110260455 1.234881932403828 1.0 14.223401266712601 -1.5228787452992454 0.01544899667668207 1.0350238616406654e-09 2.499736560829732 0.1442799666098823 0.10668073590960199 10535.128872606361 12.61276396319311 810.7285019208688 1279.381420404368 0.029999999998693894 1.5228787452992454 2.499736559794708 YRSPYS(ph)GPK ddPTM_PC-9_AZD4547_30min_R2 1 YRSPYSGPK 9 1 G3XAC6;Q14498-2;Q14498;Q5QP23;Q5QP22 G3XAC6 RBM39 RNA-binding protein 39 1 YRS(0.112)PY(0.001)S(0.886)GPK 89.679 0.044209 42351000.0 43822.0 49641.0 51895.0 70539.0 69604.0 49347.0 49690.0 59123.0 53429.0 59839.0 True False 57756.48444577555 65686.48246733633 51206.83839240936 54277.32336668608 59940.68605249536 46261.32428907928 54112.31373771493 49986.89886138197 56253.147862534635 57744.05482357408 1.0002152537129485 1.1375453744637232 0.8867897924533021 0.9399638375330598 1.0380408205768137 0.8011443676829054 0.9371062337593846 0.8656631234870391 0.9741807712396605 1.0 15.817384797626744 -5.2688363433403955 24.981066235425878 0.9253780419316899 1.0688803164054441 0.3746485108706804 0.07135268792194911 483.4955266684876 1632867.2142732474 0.017913718613316663 0.03855461001673461 5.384726587632264e-06 5.2688363433403955 0.1435022744737542 YRSPYSGPK ddPTM_PC-9_AZD4547_30min_R2 2 YRSPYSGPK 9 1 G3XAC6;Q14498-2;Q14498;Q5QP23;Q5QP22 G3XAC6 RBM39 RNA-binding protein 39 0 ; 85.29 0.016267 13731600.0 63399.0 60921.0 86461.0 116757.0 101829.0 88828.0 86313.0 97615.0 76648.0 78522.0 False True 83558.56321887931 80612.5218749137 85314.47064738612 89840.47752766806 87691.80104648498 83273.57111780536 93994.68978956302 82530.84471954736 80699.45680000664 75772.96868023682 1.1027489706982159 1.0638691248207506 1.125922240257137 1.185653394507959 1.1572966266709943 1.0989878391754875 1.2404778567700332 1.089185842352685 1.0650164327144114 1.0 16.20939565134652 -8.38244577848189 2.156350449809302 1.0050737262606615 1.137040338918367 0.44849643230817027 0.04813500122737669 0.27969675433737073 2.609343040525795 0.0474730673512568 0.013357745789195317 4.145283345287012e-09 8.38244577848189 0.13196661265770548 YS(ph)DS(ph)LLQMKAKEY(ph)ELLAK ddPTM_PC-9_AZD4547_30min_R2 1 YSDSLLQMKAKEYELLAK 18 2 O75901 O75901 RASSF9 Ras association domain-containing protein 9 3 Y(0.64)S(0.68)DS(0.68)LLQMKAKEY(1)ELLAK 50.07899999999999 0.040951 0.0 15389.0 11166.0 13318.0 20454.0 17502.0 13655.0 14909.0 12797.0 17623.0 13818.0 True False 20282.381888915163 14775.191136968982 13141.394618173394 15738.646311149841 15072.14940651072 12801.150691376948 16235.872117439978 10819.517695805447 18554.515801932437 13334.236025871858 1.5210756618948478 1.108064317168325 0.9855378735366389 1.180318563479213 1.1303346796372031 0.9600213065480027 1.2176079743854988 0.8114088932288878 1.3914944782687129 1.0 13.702847548775766 -4.7634773054650035 5.388436564499066 1.080947239491938 1.543199937374552 0.42428913720675765 0.1517828727670221 0.13521946834020926 11.956325470153145 0.03424842703880752 0.23389279942396463 1.723942175164427e-05 4.7634773054650035 0.462252697882614 YS(ph)GAYGASVSDEELK ddPTM_PC-9_AZD4547_30min_R2 5 YSGAYGASVSDEELK 15 0 A0A286YEX5;C9JRZ6;F8WAR4;Q9NX63 A0A286YEX5 CHCHD3 MICOS complex subunit MIC19 1 YS(1)GAYGASVSDEELK;YS(1)GAYGASVSDEELK;Y(0.008)S(0.992)GAYGASVSDEELK;Y(0.025)S(0.975)GAYGASVSDEELK;YS(1)GAYGASVSDEELK 192.4 3.8960000000000006e-08 83666600.0 228404.0 246678.0 282453.0 259280.0 262398.0 276054.0 297163.0 297990.0 242925.0 245100.0 True False 301031.7209016686 326411.83944879455 278707.4886684885 199507.00183606773 225968.5670191754 258792.29974056123 323609.9313189892 251942.4926289811 255765.51955878324 236519.12360263383 1.2727584827661536 1.3800653176661766 1.178371898319451 0.8435131958769276 0.9553923741017069 1.0941707198921795 1.368218883910094 1.0652098180959755 1.0813735298143776 1.0 17.85159731090333 -5.519452749699001 24.96032111635029 1.066481246135751 1.3146136211199395 0.41009586147890964 0.12827576850300945 141.9288980318811 1034030.7573462827 0.038254172728153076 0.06807281240029835 3.0237595311177046e-06 5.519452749699001 0.2481323749841886 YS(ph)GAYGASVSDEELK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 YSGAYGASVSDEELK 15 0 A0A286YEX5;C9JRZ6;F8WAR4;Q9NX63 A0A286YEX5 CHCHD3 MICOS complex subunit MIC19 1 Y(0.011)S(0.989)GAYGASVSDEELK;YS(1)GAYGASVSDEELK;Y(0.001)S(0.999)GAYGASVSDEELK;YS(1)GAYGASVSDEELK;YS(1)GAYGASVSDEELK 281.99 3.5588e-76 71703600.0 142080.2 176083.3 131129.0 138686.9 151380.6 113324.2 159625.0 119928.4 110894.4 99742.6 True False 166131.57164813578 193563.68633001117 134255.61266950163 130916.72262199626 121718.65812472974 107381.2794561474 144504.16441507885 116780.40657464328 112516.02080840661 117825.14381801256 1.409984034517583 1.6428045836208016 1.13944789982066 1.1111102297842672 1.033044850874368 0.9113613272732662 1.2264289245279727 0.9911331553731609 0.9549406617503801 1.0 16.84628791675258 -5.390122195452565 4.094586405183191 1.040133842812177 1.5242305153290574 0.7940575233081999 0.09876897420572327 0.09231080591915689 2.5799571534795187 0.02615088601859497 0.05822540617738556 4.072656712020139e-06 5.390122195452565 0.4840966725168805 YS(ph)GAYGASVSDEELK ddPTM_PC-9_Lapatinib_30min_R1 4 YSGAYGASVSDEELK 15 0 A0A286YEX5;C9JRZ6;F8WAR4;Q9NX63 A0A286YEX5 CHCHD3 MICOS complex subunit MIC19 1 YS(1)GAYGASVSDEELK;YS(1)GAYGASVSDEELK;YS(1)GAYGASVSDEELK;YS(1)GAYGASVSDEELK 236.31 5.9421e-32 71316200.0 264940.0 311508.0 245839.0 212784.0 259275.0 258057.0 250651.0 264037.0 258393.0 190509.0 True False 261161.90701595508 310786.72236499476 225627.06638598343 228432.84518661548 244024.9542542625 247020.50367024826 263628.482335238 276305.1229344581 229290.05934108247 223438.226812714 1.1688327048659453 1.3909290581038145 1.0097961732175045 1.0223534640654304 1.0921361028290126 1.1055427139479626 1.1798718871691167 1.236606317888734 1.026189934514981 1.0 17.76951650410423 YS(ph)GGNYR ddPTM_PC-9_Lapatinib_30min_R1 1 YSGGNYR 7 0 P98179 P98179 RBM3 RNA-binding protein 3 1 Y(0.334)S(0.666)GGNYR 77.72 0.029382 2797700.0 0.0 0.0 0.0 0.0 0.0 0.0 834.88 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 878.1060013007867 0.0 0.0 0.0 0.0 YS(ph)GSYNDYLR ddPTM_PC-9_AZD4547_30min_R2 2 YSGSYNDYLR 10 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 YS(0.992)GS(0.008)YNDYLR;Y(0.002)S(0.983)GS(0.014)YNDY(0.001)LR 85.522 0.011851 8825600.0 11193.2 13558.3 34699.0 41836.0 41953.0 44655.0 32928.0 57587.0 37384.0 47663.0 True False 14752.40476697675 17940.755327992716 34238.86858807617 32191.356559756743 36128.550111492645 41862.71579080462 35858.528210011646 48688.25236761338 39360.04191905136 45994.3328774881 0.3207439665723971 0.39006447546005846 0.7444149408422959 0.6998983254198429 0.7855000355745075 0.910171170485534 0.7796292709696542 1.0585706829861166 0.8557585132040496 1.0 15.489168492170931 -5.030558576419386 0.5684820362928317 0.9408134622893295 1.2521867651503682e-13 0.865226229387453 0.0831376013885988 1.0227492000326135 0.3067345841940148 0.045739488869493354 0.611740605982887 9.320547489377871e-06 5.030558576419386 -0.9408134622892043 down YS(ph)GSYNDYLR ddPTM_PC-9_Lapatinib_30min_R1 2 YSGSYNDYLR 10 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 YS(0.982)GS(0.017)YNDYLR;YS(0.953)GS(0.047)YNDYLR 79.089 0.019504 11794700.0 50362.0 41620.0 54700.0 40565.0 42492.0 32280.0 35751.0 27343.0 41409.0 26677.0 True False 49643.8286447403 41523.63144712517 50202.77714810613 43548.28542087307 39992.70410248627 30899.45964835527 37602.01184901352 28613.45560052905 36745.08236389875 31288.083905131873 1.5866688671401101 1.327138842155638 1.6045334479517892 1.391848908131133 1.2782087974369905 0.9875791608730358 1.201799763866206 0.9145160722301653 1.1744113981320479 1.0 14.933325689607765 -6.439102182228141 2.079442557599092 1.0576212469607011 1.4860923700207704 0.7637936664871325 0.11058716160875379 0.14729845896702148 1.2626901857399242 0.036712556555429536 0.041979013298169957 3.6382942307763535e-07 6.439102182228141 0.4284711230600693 YS(ph)HFAQDLWSEQS(ph)IK ddPTM_PC-9_Lapatinib_30min_R1 1 YSHFAQDLWSEQSIK 15 0 K7ERD0 K7ERD0 ZNF506 2 Y(0.01)S(0.981)HFAQDLWS(0.009)EQS(1)IK 93.181 0.040674 12212000.0 8289.5 4764.8 16745.0 6196.3 9076.9 11868.0 8553.1 6374.8 14771.0 5332.0 True False 8171.2902098918785 4753.767398348437 15368.290737569241 6651.996572250854 8543.014587872014 11360.433305659233 8995.93766736029 6670.996480351556 13107.334434474358 6253.629095556592 1.3066477216721804 0.7601613920029483 2.4574995578949372 1.0637018074796465 1.36608910719411 1.8166145020866673 1.4385147455822407 1.0667400286165865 2.0959564812994023 1.0 12.610477939826966 YS(ph)NT(ph)T(ph)TLASWVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSNTTTLASWVR 12 0 O00237 O00237 RNF103 E3 ubiquitin-protein ligase RNF103 3 Y(0.414)S(0.602)NT(0.899)T(0.899)T(0.179)LAS(0.007)WVR 54.486000000000004 0.044414 665590.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 YS(ph)PPAISPLVSEK ddPTM_PC-9_AZD4547_30min_R2 4 YSPPAISPLVSEK 13 0 Q14694;Q14694-3;Q14694-2 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 Y(0.036)S(0.964)PPAISPLVSEK;Y(0.035)S(0.964)PPAISPLVSEK;Y(0.001)S(0.999)PPAISPLVSEK;Y(0.003)S(0.996)PPAISPLVSEK 150.26 4.9634e-05 67898000.0 180823.0 197788.0 188583.0 165703.0 177894.0 217718.0 227708.0 258660.0 213488.0 165710.0 True False 238320.95264795003 261719.1030448523 186082.2662020567 127502.73343582965 153196.48877395873 204104.05904249017 247973.5708711535 218690.04041549115 224772.5398356096 159908.54333819836 1.490357848760547 1.6366799270463606 1.1636793276798367 0.7973478513037787 0.9580256662707258 1.2763799530761817 1.550721216606308 1.3675944752556024 1.4056318389457605 1.0 17.28688749332006 -7.003026076382652 24.97251935252111 1.369038456802443 1.1985192370493591 0.03850589691667805 0.2583956639853928 366.5610706166742 3025045.1706378637 0.10267195391767342 0.0888485669057531 9.930564204548248e-08 7.003026076382652 -0.17051921975308382 YS(ph)PPAISPLVSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 YSPPAISPLVSEK 13 0 Q14694;Q14694-3;Q14694-2 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 Y(0.071)S(0.929)PPAISPLVSEK;Y(0.027)S(0.973)PPAISPLVSEK;Y(0.001)S(0.999)PPAISPLVSEK 143.46 8.6004e-05 58712000.0 137502.0 208003.0 162742.0 133126.0 152032.0 104763.0 156193.0 87811.0 100729.0 84795.0 True False 160778.37281170752 228652.1631960629 166622.38648247163 125667.3818203153 122242.42097084392 99269.04385527871 141397.26830060672 85506.05429344511 102201.97106445428 100167.6622631494 1.6050925935490874 2.2826944148439168 1.6634349122048964 1.2545703771160783 1.2203780961734152 0.9910288571424385 1.4116059525193219 0.8536293286830741 1.0203090374212844 1.0 16.612057304102734 -5.72068699788159 2.383248429041355 1.0943130462160087 1.9556123152255445 0.7342233894799087 0.21039181398828938 0.13702127996268185 1.5829274832328188 0.05984336007340986 0.11508695239948465 1.9024489075333411e-06 5.72068699788159 0.8612992690095358 YS(ph)PPAISPLVSEK ddPTM_PC-9_Lapatinib_30min_R1 3 YSPPAISPLVSEK 13 0 Q14694;Q14694-3;Q14694-2 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 Y(0.027)S(0.973)PPAISPLVSEK;Y(0.126)S(0.874)PPAISPLVSEK;Y(0.007)S(0.993)PPAISPLVSEK 171.11 0.00022793 47299000.0 96861.0 161442.0 134368.0 127625.0 176022.0 164246.0 174444.0 176206.0 139270.0 140392.0 True False 95479.74437786826 161068.19096796715 123320.78171547975 137010.96824451958 165668.7320325668 157221.58145612653 183475.85675895275 184393.1740316286 123583.94602188354 164658.57013941897 0.5798650158143854 0.9781950057721758 0.7489484550428328 0.8320913277001633 1.0061348880431338 0.954833880331917 1.1142806390435729 1.119851665634531 0.7505466974311942 1.0 17.329118077629538 -6.193509397715944 3.6245035230915725 1.0024019579967391 0.7897110388456864 0.3714179639963412 0.1317555057154959 0.2672252967447136 6.933735850431881 0.03949880430171357 0.051318598546116125 6.404579225243794e-07 6.193509397715944 -0.21269091915105276 YS(ph)PPRDDDKVDNQAK ddPTM_PC-9_Lapatinib_30min_R1 1 YSPPRDDDKVDNQAK 15 2 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 Y(0.424)S(0.576)PPRDDDKVDNQAK 78.529 0.033186 34605000.0 21659.0 25848.0 17260.0 19330.0 20821.0 21115.0 15179.0 19931.0 19268.0 14710.0 True False 21350.138688225852 25788.15054409638 15840.949425526725 20751.592682989703 19596.34971566098 20211.96067146906 15964.894348582597 20857.067021692746 17097.834938964996 17252.60390015707 1.2375023974225408 1.4947396168911986 0.9181773091876587 1.2028093152246297 1.1358488161594305 1.1715310215453938 0.9253614376689683 1.2089228468001203 0.9910292404504419 1.0 14.074526500880186 -5.257064729515959 24.999871351883783 1.0823397641124697 1.366121008138696 0.49736783954067354 0.11880613858192896 286.97722711713516 1639976.683375673 0.028571565756041372 0.07033766650906917 5.532676411736743e-06 5.257064729515959 0.2837812440262264 YS(ph)PS(ph)QNSPIHHIPSR ddPTM_PC-9_AZD4547_30min_R2 2 YSPSQNSPIHHIPSR 15 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 Y(0.271)S(0.741)PS(0.557)QNS(0.431)PIHHIPSR;Y(0.245)S(0.779)PS(0.923)QNS(0.053)PIHHIPSR 82.865 0.015347 35271600.0 43980.0 72500.0 92719.0 78952.0 80659.0 97946.0 82710.0 115949.0 85742.0 66789.0 True False 57964.72515917142 95934.20718522774 91489.48547848157 60750.83619624044 69460.89012568546 91821.42113640482 90071.02976949896 98031.746292955 90274.1470742377 64450.73743898944 0.899364808882787 1.4884888986109939 1.419525813263 0.9425933450916459 1.0777361576574471 1.4246760360705741 1.397517442756373 1.5210337412470123 1.40066895525739 1.0 15.975909245405367 -6.7736466029367275 24.978286267864693 1.3843900126632858 1.1852075012512144 0.13930724762208724 0.2162151675932441 426.30720594192354 872299.790222754 0.07682747018726685 0.06824601342924465 1.684043855309678e-07 6.7736466029367275 -0.19918251141207133 YS(ph)PS(ph)QNSPIHHIPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSPSQNSPIHHIPSR 15 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 Y(0.344)S(0.823)PS(0.824)QNS(0.009)PIHHIPSR 80.316 0.0045218 5152300.0 12922.0 17526.0 23999.0 16684.0 19964.0 18492.0 15518.0 14548.0 14719.0 13883.0 True False 15109.439378866386 19265.865454701117 24571.22717671433 15749.249570257798 16052.197512773133 17522.246966694496 14048.02269940916 14166.130414880148 14934.237529387774 16399.878002232468 0.9213141327520595 1.1747566324626628 1.4982567049199706 0.9603272395144584 0.9787998124490922 1.068437641079357 0.8565931220644961 0.8637948656052047 0.9106310136791761 1.0 14.001397462305682 -5.953494889729507 24.999556706540652 0.9437595044261727 1.2013607741082146 0.3931614881484887 0.1422344432057461 124.78042457533957 67076.84977577826 0.041281089501493624 0.06122972724204277 1.1130254895094173e-06 5.953494889729507 0.2576012696820419 YS(ph)PS(ph)QNSPIHHIPSR ddPTM_PC-9_Lapatinib_30min_R1 1 YSPSQNSPIHHIPSR 15 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 Y(0.24)S(0.759)PS(0.835)QNS(0.166)PIHHIPSR 135.57 0.0016162 11857000.0 17611.0 38955.0 50246.0 40131.0 55279.0 55563.0 56955.0 67101.0 51106.0 43942.0 True False 17359.863910538144 38864.802090888064 46114.96783516895 43082.36761309151 52027.59790269552 53186.700013679154 59903.85121704467 70218.75742424403 45349.90410996183 51537.316150965475 0.3368406662793001 0.7541099341891127 0.8947879183325509 0.8359451137675207 1.0095131409306197 1.032003681718354 1.1623393628331664 1.3624837820144926 0.8799430683802162 1.0 15.653329789146884 -4.780171525156346 0.6515666805356543 1.1099409609928463 7.817677925311041e-16 0.7249629833176514 0.13451807150713108 1.7964153095328501 0.5760317644326605 0.06360382865065528 1.4956999311574184 1.658931580903527e-05 4.780171525156346 -1.1099409609928454 down YS(ph)PSQNS(ph)PIHHIPSR ddPTM_PC-9_AZD4547_30min_R2 1 YSPSQNSPIHHIPSR 15 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 Y(0.081)S(0.747)PS(0.197)QNS(0.975)PIHHIPSR 78.708 0.025917000000000003 7664600.0 27829.0 30782.0 57102.0 52720.0 52624.0 57582.0 35683.0 103120.0 44206.0 55020.0 True False 36678.043120840885 40731.679525181775 56344.79017021602 40566.21851588049 45318.06595636047 53981.38843726599 38858.717872869434 87185.17346186272 46542.638911662354 53093.766546784645 0.690816370854407 0.7671650021154599 1.0612317383918632 0.7640486097390501 0.8535477684829074 1.016718005675849 0.7318885134779106 1.6420981055287864 0.8766121136018927 1.0 15.696254871465339 YS(ph)PSQNS(ph)PIHHIPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YSPSQNSPIHHIPSR 15 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 Y(0.038)S(0.675)PS(0.292)QNS(0.995)PIHHIPSR;Y(0.321)S(0.659)PS(0.24)QNS(0.779)PIHHIPSR;Y(0.007)S(0.988)PS(0.444)QNS(0.562)PIHHIPSR;Y(0.129)S(0.755)PS(0.139)QNS(0.976)PIHHIPSR 129.2 3.5305e-05 41221000.0 150490.0 240767.0 306733.0 211190.0 265219.0 170647.0 203158.0 140764.0 184784.0 131145.0 True False 175964.98468701495 264668.7565863296 314046.678011381 199357.7089872182 213251.24084052187 161697.9709131253 183913.40350345167 137069.0941517864 187486.11642301723 154920.5503567511 1.135840172796977 1.7084160621483095 2.0271466715564475 1.2868383731411823 1.3765200313931678 1.0437477180449406 1.187146592753097 0.8847702505325707 1.2102081743918036 1.0 17.241169006112877 -6.3958343049787185 1.6677844228977337 1.062561755554017 1.612867025971252 0.47660286923764317 0.23725360578339325 0.3151073880305705 1.7495346147061448 0.08986124821720844 0.10852978124818471 4.019441340924309e-07 6.3958343049787185 0.5503052704172351 YS(ph)PSQNS(ph)PIHHIPSR ddPTM_PC-9_Lapatinib_30min_R1 2 YSPSQNSPIHHIPSR 15 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 Y(0.067)S(0.933)PS(0.146)QNS(0.855)PIHHIPSR;Y(0.037)S(0.663)PS(0.301)QNS(1)PIHHIPSR 118.44 0.00025181 84712000.0 46540.0 116986.0 129504.0 80903.0 127083.0 132434.0 115139.0 142130.0 122973.0 100663.0 True False 45876.331065609265 116715.1261045984 118856.6810198964 86852.87650449625 119608.22779479093 126770.10653873223 121100.3340405461 148733.87867107464 109122.48577690183 118062.46542498385 0.3885767665487114 0.9885879113608589 1.0067270795341572 0.7356518957304176 1.013092750216954 1.0737545254743233 1.0257310281013274 1.259789706539537 0.9242775456543179 1.0 16.849190848552105 -4.761303908292693 6.309228752624367 1.007408035539622 0.3691913613587902 0.6949078703470231 0.12218185147437584 0.07421174554223878 12.873604481149048 0.03204422548982236 0.20406987774331853 1.7325911499837218e-05 4.761303908292693 -0.6382166741808317 YS(ph)PSQNS(ph)PIHHIPSRR ddPTM_PC-9_Lapatinib_30min_R1 2 YSPSQNSPIHHIPSRR 16 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 Y(0.069)S(0.734)PS(0.332)QNS(0.865)PIHHIPSRR;Y(0.129)S(0.651)PS(0.272)QNS(0.939)PIHHIPS(0.009)RR 62.739 0.011473 14508400.0 44492.0 40218.0 56750.0 43084.0 50728.0 50225.0 36241.0 44838.0 55785.0 34147.0 True False 43857.535921166476 40124.87769198657 52084.23406133502 46252.541084010736 47744.278775085295 48076.9938301934 38117.381651425116 46921.33716916658 49501.90585790752 40049.26345198258 1.0950897005571616 1.0018880307273228 1.3005041684170264 1.1548911789467897 1.1921387476283734 1.2004463924245634 0.9517623637979332 1.1715905144029262 1.236025374530502 1.0 15.289488089750392 YS(ph)PSQNSPIHHIPSR ddPTM_PC-9_AZD4547_30min_R2 3 YSPSQNSPIHHIPSR 15 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 Y(0.006)S(0.972)PS(0.023)QNSPIHHIPSR;Y(0.194)S(0.581)PS(0.217)QNS(0.008)PIHHIPSR;Y(0.192)S(0.64)PS(0.168)QNSPIHHIPSR 103.99 0.0010335999999999998 22323000.0 13240.699999999999 14070.0 34637.5 41462.0 32220.1 41884.0 21559.100000000002 57936.0 31577.0 33969.4 True False 17450.967176331087 18617.852346153835 34178.184118259545 31903.57648151434 27746.895274409555 39264.98685885256 23477.818134489247 48983.32243683554 33246.09575427683 32780.14164548065 0.5323639954050359 0.567961314734607 1.0426490674719717 0.973259262469137 0.8464544044529769 1.1978284683301836 0.7162207652548719 1.4942986813966006 1.0142145239589109 1.0 15.000534467995088 -4.646973683098318 0.6845642373085756 1.0843104792272493 1.0572881225491139e-12 0.4557786131048641 0.20308700185877826 3.2169419161872836 1.0051440693900808 0.08633724946752364 2.832658385255937 2.2543758162118058e-05 4.646973683098318 -1.084310479226192 YS(ph)PSQNSPIHHIPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YSPSQNSPIHHIPSR 15 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 YS(0.976)PS(0.024)QNSPIHHIPSR;Y(0.409)S(0.551)PS(0.039)QNSPIHHIPSR 172.95 1.5996999999999999e-21 4554000.0 10291.2 14901.8 31012.1 22412.1 31425.5 19302.9 19105.8 16237.0 20632.2 13895.7 True False 12033.29689953489 16381.152221434731 31751.546078044186 21156.422698008562 25267.898864839295 18290.62194318662 17295.960309986585 15810.795954523572 20933.906892712428 16414.88041169933 0.7330724682562069 0.9979452673782162 1.9343147974086974 1.2888563405512115 1.5393288425561833 1.1142708009100326 1.0536756818319117 0.96319897300347 1.2753006033350243 1.0 14.002716618946984 -6.971240141834662 23.718119769864668 1.0719764319610277 1.3177636898422707 0.11204085798162677 0.3054338629733968 268.92591494146666 221780.2081782787 0.11346088759628076 0.10006076682160642 1.0684639119269152e-07 6.971240141834662 0.245787257881243 YS(ph)PSQNSPIHHIPSR ddPTM_PC-9_Lapatinib_30min_R1 1 YSPSQNSPIHHIPSR 15 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 Y(0.283)S(0.361)PS(0.347)QNS(0.009)PIHHIPSR 66.568 0.027270999999999997 4632900.0 2613.9 5927.0 3951.5 6200.0 5384.6 5593.7 4633.6 6704.2 6210.3 4958.0 True False 2576.625306669449 5913.2763956537965 3626.6229232311043 6655.968682593696 5067.888414530911 5354.470490551577 4873.505135621079 7015.701606885379 5510.830616641805 5814.983693880272 0.4431010373049037 1.0169033495101574 0.623668631615904 1.1446237913957493 0.8715223775888471 0.9208057618780012 0.8380943769025506 1.2064868925202235 0.9476949389284515 1.0 12.505559430824716 -4.756611243468256 24.981805430999362 0.9473313322176432 0.4431002618375293 0.49596606013627653 0.15389646624259745 124.80162307066114 645674.0307969518 0.03718333366673638 0.2963849302316597 1.7514137564014435e-05 4.756611243468256 -0.5042310703801138 YS(ph)PSQNSPIHHIPSRR ddPTM_PC-9_AZD4547_30min_R2 1 YSPSQNSPIHHIPSRR 16 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 Y(0.019)S(0.739)PS(0.242)QNSPIHHIPSRR 56.818999999999996 0.022018 5016000.0 3977.6 3763.3 20774.0 25440.0 22578.0 25655.0 10055.0 29218.0 14283.0 16245.0 True False 5242.394060780359 4979.713129657478 20498.523186509537 19575.201044081936 19443.434424648574 24050.788794381213 10949.875520883952 24703.029462846258 15037.970220677582 15676.267494593176 0.3344159611073546 0.31765936192240957 1.3076150425207775 1.2487156812572586 1.240310197013078 1.5342165348145822 0.6985001706981984 1.5758234204262245 0.959282573218673 1.0 13.936294475478611 -5.258086639675909 24.95728889746546 1.2139627556201302 0.32603755047782645 0.6604054494442582 0.2491309894192476 145.28541159286993 1081469.812564771 0.05952376466079879 0.14462604052356126 5.519673134522762e-06 5.258086639675909 -0.8879252051423038 YS(ph)PVSK ddPTM_PC-9_Lapatinib_30min_R1 1 YSPVSK 6 0 Q12959-3;Q12959;Q12959-5;A0A590UK48;Q12959-8;A0A590UJX2;A0A590UJS9;A0A590UJ68;A0A590UJ18;Q12959-9;Q12959-6;A0A590UJ08;A0A590UJR5;A0A590UJC5;A0A590UKA8;A0A0C4DFT3;A0A590UJD9;A0A590UJR4;A0A590UJ81;Q12959-7;Q12959-2;Q12959-4;A0A590UK81;A0A590UJ29;A0A590UJ64;A0A590UJ25;A0A590UK02;A0A590UK70;A0A590UJL2;E7EQD7;H7C166 Q12959-3 DLG1 Disks large homolog 1 1 Y(0.143)S(0.854)PVS(0.002)K 87.696 0.039516 67501000.0 564390.0 933390.0 720990.0 767970.0 826210.0 600980.0 517030.0 680420.0 741040.0 529490.0 True False 556341.6951035496 931228.7928023117 661712.9853018846 824449.0756728189 777613.9521913579 575277.4863528057 543799.2835527812 712034.7971953321 657576.2717028562 621011.6409989243 0.895863552909652 1.4995351637924044 1.0655403886431025 1.3275903722942402 1.2521729076455506 0.9263553987932446 0.8756668114595346 1.1465723831682013 1.058879138956423 1.0 19.244260786769864 -6.753858554358477 24.9982827005107 1.0027912696965253 1.223042979336695 0.2843172962459055 0.16306742337663244 212.5177912705958 700790.9397256516 0.05191631841508813 0.05095998039539187 1.7625499989529568e-07 6.753858554358477 0.2202517096401697 YS(ph)SDDTLDR ddPTM_PC-9_AZD4547_30min_R2 1 YSSDDTLDR 9 0 O95171-2;O95171;O95171-3;F2Z2X8 O95171-2 SCEL Sciellin 1 Y(0.006)S(0.497)S(0.497)DDT(0.001)LDR 97.59700000000001 0.004732500000000001 13928000.0 35491.0 34587.0 41948.0 67112.0 47237.0 51057.0 40609.0 53023.0 34174.0 46825.0 True False 46776.399741340465 45766.57136435127 41391.7421116637 51640.36527006392 40678.95791997186 47864.39771875741 44223.12232994297 44829.51369732685 35980.36787239627 45185.67100242075 1.0352042739131724 1.0128558533943073 0.916036902704094 1.1428482553085773 0.9002623401961332 1.0592826587922786 0.9786979223474138 0.9921179148789266 0.7962782686234466 1.0 15.463577726279535 -8.037998942648068 22.944632058562565 0.896825199686697 1.0049166801582508 0.22453619821594673 0.07953328963655408 288.8984396841054 174439.9474286849 0.049011409367781616 0.018540752435451214 9.162227207943315e-09 8.037998942648068 0.1080914804715537 YS(ph)SDDTLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSSDDTLDR 9 0 O95171-2;O95171;O95171-3;F2Z2X8 O95171-2 SCEL Sciellin 1 YS(0.486)S(0.486)DDT(0.027)LDR 79.48899999999999 0.020071000000000002 26567000.0 46740.0 68886.0 64000.0 77852.0 47566.0 88073.0 66869.0 64645.0 75878.0 70004.0 True False 54652.158842920195 75724.54682828613 65526.00272135161 73490.20483958932 38245.78375538804 83454.29683634458 60534.68423036421 62948.13724703922 76987.57220292717 82695.17104864083 0.6608869435770816 0.9157069979787016 0.7923800373157168 0.8886879839254798 0.4624911378790436 1.0091798079389334 0.7320219967228565 0.7612069296043114 0.9309802643451033 1.0 16.33551546580714 -8.406668768130565 3.5792606254742982 0.997233447940586 0.7823706798401068 0.22426199632858546 0.14181515050315477 0.3341416867905839 7.428942313588377 0.12863823304752947 0.03412290717593554 3.92040768515772e-09 8.406668768130565 -0.21486276810047922 YS(ph)SPTAGSAK ddPTM_PC-9_AZD4547_30min_R2 1 YSSPTAGSAK 10 0 P28749;P28749-2 P28749 RBL1 Retinoblastoma-like protein 1 1 YS(0.487)S(0.487)PT(0.025)AGSAK 98.75399999999999 0.0046373000000000004 25198000.0 75438.0 80195.0 113880.0 149200.0 125700.0 112450.0 130130.0 151810.0 108210.0 131150.0 True False 99425.7147921231 106116.46545130113 112369.87679212971 114804.2451170215 108248.72473993825 105418.48372356893 141711.31790478653 128351.25274675527 113929.75968490656 126558.47841895295 0.7856108577964181 0.8384777280587905 0.8878889679768905 0.9071240943414253 0.8553257442112808 0.8329626354592916 1.119729943620785 1.0141655806090495 0.9002143602561268 1.0 16.94944463430147 -7.2390121306488195 24.997143652521377 1.0097079439952983 0.8550448359347689 0.6383970584676311 0.05795001724757034 533.4042296398587 594526.7466302299 0.022935740590117052 0.017751624395883812 5.767503534622437e-08 7.2390121306488195 -0.1546631080605294 YS(ph)SPTAGSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YSSPTAGSAK 10 0 P28749;P28749-2 P28749 RBL1 Retinoblastoma-like protein 1 1 YS(0.487)S(0.36)PT(0.152)AGS(0.001)AK;Y(0.009)S(0.582)S(0.399)PT(0.006)AGS(0.004)AK 101.39 0.0036191 58650000.0 93986.0 117415.0 137971.0 150602.0 169698.0 147551.0 164662.0 165853.0 145487.0 108353.0 True False 109895.97349188494 129071.18523129832 141260.75189793145 142164.2581982717 136446.89508728567 139813.16581130982 149064.02331035654 161499.53448577912 147614.47214063755 127996.54117812365 0.8585854936419771 1.0083958835393776 1.10362944652816 1.110688280243697 1.0660201739154986 1.0923198746186573 1.1645941518287966 1.2617492082151793 1.1532692272927363 1.0 16.96574529956373 -3.84082422266939 0.7273270366443344 1.141372117450473 5.205054662300021e-11 0.6088248418969142 0.06497328923710198 6.553127987793702 0.9532469397459927 0.026403101077893554 8.416951324286368 0.0001442699154690019 3.84082422266939 -1.1413721173984224 YS(ph)SSGSPANSFHFK ddPTM_PC-9_AZD4547_30min_R2 2 YSSSGSPANSFHFK 14 0 O00418;H3BRH4 O00418 EEF2K Eukaryotic elongation factor 2 kinase 1 Y(0.03)S(0.826)S(0.113)S(0.017)GS(0.014)PANSFHFK;Y(0.001)S(0.307)S(0.307)S(0.222)GS(0.162)PANS(0.001)FHFK 94.20299999999999 0.0019858000000000002 33890000.0 38517.0 35828.0 114726.0 231960.0 153346.0 136627.0 53877.0 147495.0 76502.0 116931.0 True False 50764.60479663043 47408.70034527361 113204.65827936337 178485.20574627537 132056.55484463426 128083.69209159729 58671.948626421196 124703.0368479195 80545.73953807156 112837.2812810263 0.4498921298023737 0.42015103347979577 1.0032558122117645 1.581792858884556 1.170327336368035 1.135118558666786 0.5199695345397066 1.105158112923166 0.7138220508651639 1.0 16.78388428537339 -5.273950995436832 6.710293053758565 1.0439243844343076 0.4325201707599738 0.4440711817715972 0.26538752069407573 0.12981113644709352 32.11608428574684 0.07402472222648858 0.16824111397670846 5.32168304248026e-06 5.273950995436832 -0.6114042136743338 YS(ph)SSSIPEPFGSR ddPTM_PC-9_Lapatinib_30min_R1 1 YSSSSIPEPFGSR 13 0 Q8WUF5;K7EN03 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 Y(0.001)S(0.978)S(0.018)S(0.003)SIPEPFGSR 106.79 0.0019055 0.0 10461.0 9160.6 8404.6 7240.5 10272.0 11235.0 13255.0 10649.0 8631.3 11469.0 True False 10311.824221687546 9139.38919352559 7713.606230694202 7772.99052359994 9667.82115552901 10754.50524006417 13941.279042786891 11143.791416085802 7659.152102381592 13451.401368518114 0.7665985081540658 0.6794376989534764 0.5734425744478383 0.5778573035365652 0.7187222275707081 0.7995081661330986 1.0364183374540659 0.8284483609393233 0.5693943621597077 1.0 13.715468860293798 -6.701110150879188 3.0622707525015804 0.8511445559301576 0.6469976521929445 0.3508545634133958 0.128039526576748 0.3018171958717181 5.749289343020794 0.04751735695099312 0.04577415981455175 1.9901685050036274e-07 6.701110150879188 -0.20414690373721311 YS(ph)TPHAFTFNTSSPSSEGSLSQR ddPTM_PC-9_AZD4547_30min_R2 2 YSTPHAFTFNTSSPSSEGSLSQR 23 0 P04049;P04049-2;H7C155 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 Y(0.065)S(0.725)T(0.21)PHAFTFNTSSPSSEGSLSQR;Y(0.219)S(0.505)T(0.274)PHAFT(0.002)FNTSSPSSEGSLSQR 107.09 1.0964e-06 18155200.0 26011.0 31155.4 40048.0 40655.0 34603.7 39570.0 37088.3 53512.0 45224.0 41711.0 True False 34281.956937589996 41225.773772946784 39516.937353101646 31282.617863488642 29799.57355834047 37095.681644656586 40389.08685044264 45242.949983428975 47614.448313374145 40250.71058584031 0.8517106018409015 1.0242247446794017 0.9817699309637332 0.7771941764052601 0.7403490056352839 0.9216155716194083 1.0034378589244337 1.1240286028476942 1.1829467758545438 1.0 15.296726632332451 -7.459205947864223 2.4912168698813657 1.113902841975965 0.8815862202769948 0.5461778435613995 0.0902697257902101 0.2431125096814135 2.9704101230904505 0.05214558908601609 0.02977950482120631 3.473713945278218e-08 7.459205947864223 -0.23231662169897005 YS(ph)TPHAFTFNTSSPSSEGSLSQR ddPTM_PC-9_Lapatinib_30min_R1 2 YSTPHAFTFNTSSPSSEGSLSQR 23 0 P04049;P04049-2;H7C155 P04049 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 Y(0.378)S(0.487)T(0.135)PHAFTFNTSSPSSEGSLSQR;Y(0.276)S(0.362)T(0.362)PHAFTFNTSSPSSEGSLSQR 104.49 1.5194e-06 14319200.0 27595.0 41758.0 53623.0 42972.0 56814.0 56569.0 60263.0 60100.0 59424.0 48612.0 True False 27201.490239696766 41661.311916603874 49214.32393076591 46132.304230389724 53472.31222062162 54149.6757387797 63383.12327087637 62892.46540583682 52731.04335753874 57014.51942858157 0.4770975974597195 0.7307140765921973 0.8631893143011323 0.8091325629461229 0.937871839603997 0.9497523838047872 1.111701438618146 1.103095598036535 0.924870434514344 1.0 15.799041745145585 -4.478534632888142 0.5221300385885045 1.0377076555368585 8.765959231614099e-13 0.8512101108615179 0.06866181605799485 2.1865706426504996 0.36196430738786917 0.04222944373598608 1.4822991139935593 3.322502887981944e-05 4.478534632888142 -1.0377076555359819 down YS(ph)TSGSSGLTTGK ddPTM_PC-9_AZD4547_30min_R2 2 YSTSGSSGLTTGK 13 0 D6RAW4;A0A087WYS0;B9A067;Q16891-3;Q16891-2;Q16891-4;Q16891 D6RAW4 IMMT MICOS complex subunit MIC60 1 Y(0.1)S(0.894)T(0.004)SGS(0.002)SGLTTGK;Y(0.077)S(0.68)T(0.005)S(0.006)GS(0.116)S(0.116)GLTTGK 104.55 0.0032265999999999996 0.0 16332.2 18097.0 21320.1 21029.3 21309.1 17425.5 20546.4 20746.7 18587.1 20004.4 True False 21525.499869136413 23946.501343876746 21037.381543694133 16181.319784446232 18350.699286840234 16335.88073032508 22374.989796349102 17540.77422673804 19569.57615968327 19304.052044865468 1.1150767631121161 1.2404909232642731 1.0897909669327535 0.8382343637925579 0.9506138526870161 0.846241021955291 1.159082546210833 0.9086576323960738 1.0137548383210264 1.0 14.23661608981211 -5.5461031295748295 7.931021079857527 0.9590036485052323 1.1749668494425176 0.4925784497554129 0.09083524212439287 0.138242062692148 37.53155132015585 0.024133124981808207 0.04265285002341044 2.8437857287596853e-06 5.5461031295748295 0.21596320093728527 YS(ph)TSGSSGLTTGK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSTSGSSGLTTGK 13 0 D6RAW4;A0A087WYS0;B9A067;Q16891-3;Q16891-2;Q16891-4;Q16891 D6RAW4 IMMT MICOS complex subunit MIC60 1 Y(0.002)S(0.987)T(0.01)SGS(0.001)SGLTTGK 108.23 0.00092009 1797000.0 8483.5 9779.4 9070.4 7233.9 9534.4 8025.5 7328.0 9411.1 5681.6 6916.5 True False 9919.588993237348 10750.234202196969 9286.672735683558 6828.608035620227 7666.202763263083 7604.628651914696 6633.838789874363 9164.068596884688 5764.68265146882 8170.4066990161255 1.214087542843107 1.3157526422144328 1.1366230688127008 0.8357733326105448 0.9382890039226862 0.9307527681370427 0.8119349543117854 1.121617189262833 0.7055563895201201 1.0 12.996192177971881 -5.5898045233452835 4.201685638773396 0.910577884709729 1.2591464603586255 0.6510915195534301 0.10837388803423821 0.1162264223614639 4.054809536756907 0.02771882096350658 0.05114800510920259 2.5715529825126718e-06 5.5898045233452835 0.34856857564889654 YSAPPDVYLDEAPS(ph)SPDVK ddPTM_PC-9_Lapatinib_30min_R1 1 YSAPPDVYLDEAPSSPDVK 19 0 F8W9F9;H0Y7T5;Q9Y3S1-2;Q9Y3S1-4;Q9Y3S1;H0Y7R3;H0Y7J9;H0Y493;E9PCD1 F8W9F9 WNK2 Serine/threonine-protein kinase WNK2 1 YSAPPDVY(0.003)LDEAPS(0.499)S(0.499)PDVK 75.08800000000001 0.004147100000000001 4731300.0 15108.0 13897.0 13053.0 11653.0 12854.0 12050.0 11478.0 11808.0 11916.0 13720.0 True False 14892.557149532118 13864.822350329132 11979.832726037097 12510.000493268431 12097.952991936327 11534.649589921963 12072.274677714666 12356.642787223316 10573.894598957175 16091.483719249149 0.9254930999132892 0.8616248564912374 0.7444827919569926 0.7774298946904173 0.7518233373013558 0.7168170313669612 0.7502275668509936 0.7678995301372927 0.6571112262512091 1.0 13.974009735798168 -5.069641359150514 2.846589067972129 0.7591105993112116 0.9228406640526532 0.2577257049087788 0.08445038384240344 0.3256053986402851 4.854811153780731 0.020398183160224733 0.08924268190330568 8.518411992038423e-06 5.069641359150514 0.16373006474144158 YSAPPDVYLDEAPSS(ph)PDVK ddPTM_PC-9_AZD4547_30min_R2 2 YSAPPDVYLDEAPSSPDVK 19 0 F8W9F9;H0Y7T5;Q9Y3S1-2;Q9Y3S1-4;Q9Y3S1;H0Y7R3;H0Y7J9;H0Y493;E9PCD1 F8W9F9 WNK2 Serine/threonine-protein kinase WNK2 1 YSAPPDVYLDEAPS(0.197)S(0.803)PDVK;YSAPPDVYLDEAPS(0.322)S(0.678)PDVK 159.04 9.8278e-06 4418900.0 43286.7 47112.0 50670.0 71389.0 66624.0 54842.1 63390.0 68028.0 62414.6 60132.7 True False 57050.97018070727 62340.03267462681 49998.082692810116 54931.36899905528 57374.407613951 51412.814817397535 69031.58719729815 57515.83572792477 65713.7083340687 58027.47247596936 0.9831717244678115 1.074319283860647 0.8616277869678983 0.9466441782692455 0.9887455918006972 0.8860081720548637 1.1896362921181147 0.9911828531174355 1.132458567125811 1.0 15.824448469809003 -7.2495007727170195 24.99892364744193 1.0775846721259679 0.9587675960495459 0.37617298683212597 0.07666476850679647 816.1419119327207 1708967.849856001 0.02853723530676104 0.02193593307948768 5.6298811569861065e-08 7.2495007727170195 -0.118817076076422 YSASPLTLPPAGSAPS(ph)PR ddPTM_PC-9_Lapatinib_30min_R1 1 YSASPLTLPPAGSAPSPR 18 0 Q69YU3 Q69YU3 ANKRD34A Ankyrin repeat domain-containing protein 34A 1 YSASPLT(0.001)LPPAGS(0.208)APS(0.791)PR 69.485 0.010953000000000001 22159000.0 11597.0 39832.0 63424.0 57545.0 58517.0 55087.0 45393.0 47263.0 57121.0 50026.0 True False 11431.624653370664 39739.7714512708 58209.52354371999 61777.051264492635 55075.14510884845 52731.05742406896 47743.22743034518 49459.01152206431 50687.431469203846 58672.92744454501 0.19483644589193744 0.6773101868631155 0.992101912738835 1.0529055555116371 0.9386807085926124 0.8987289320770293 0.813718174799952 0.8429613737751662 0.8638981158237129 1.0 15.840407355611289 -4.833458290902477 2.6181754835567332 0.9186488424362315 0.09200509548434863 0.903128581237629 0.07297051603045158 0.133108750788957 1.3146884754513661 0.021663848770949765 0.23387272948110338 1.4673770051886168e-05 4.833458290902477 -0.8266437469518828 down YSCPES(ph)PSQELGGPLPSPGPR ddPTM_PC-9_AZD4547_30min_R2 2 YSCPESPSQELGGPLPSPGPR 21 0 A0A494BZV2;A0A1W2PPU9 A0A494BZV2 1 YSCPES(0.969)PS(0.031)QELGGPLPSPGPR;Y(0.001)S(0.018)CPES(0.95)PS(0.03)QELGGPLPS(0.001)PGPR 159.47 7.2230999999999995e-06 42795000.0 74343.0 77442.0 123069.0 152914.0 130175.0 114604.0 95508.0 148416.0 94211.0 118416.0 True False 97982.52756953801 102473.61203915032 121437.02464814385 117662.03979774936 112102.44823406065 107437.79376305861 104008.02697648756 125481.71746039379 99190.80112443143 114270.29188302548 0.8574628274323418 0.8967651202295781 1.062717375155169 1.0296817996946739 0.9810288079846337 0.9402075726999888 0.910193062978757 1.0981132137900291 0.8680366479326892 1.0 16.802090853283048 -5.068502445272232 6.810384771040617 0.9866632797631583 0.8666047526614297 0.31732353226078713 0.06514789547011508 0.24132864609849483 20.163016835871677 0.0161984473132444 0.04451158453191029 8.540780385635436e-06 5.068502445272232 -0.1200585271017286 YSCPES(ph)PSQELGGPLPSPGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 YSCPESPSQELGGPLPSPGPR 21 0 A0A494BZV2;A0A1W2PPU9 A0A494BZV2 1 YSCPES(0.971)PS(0.029)QELGGPLPSPGPR;Y(0.003)S(0.004)CPES(0.964)PS(0.029)QELGGPLPSPGPR;YS(0.001)CPES(0.58)PS(0.418)QELGGPLPSPGPR 166.61 1.0595e-31 27319000.0 84298.1 87428.3 101956.9 106308.4 115196.1 90465.4 65431.3 80785.3 68736.6 63907.6 True False 98568.10336663206 96107.60383049438 104387.93916969628 100352.28500448304 92624.25114712323 85721.2351687651 59233.17358241082 78664.77147410058 69741.74273812854 75493.54198771673 1.3056494737347164 1.2730572880807698 1.3827399857153457 1.3292830401415128 1.226916219697226 1.1354777231503124 0.7846124585338495 1.0420066326587223 0.9238107115106078 1.0 16.204065615499914 -6.886718779840552 2.3946504323212956 0.9413545763081601 1.3158707097113 0.844048340707855 0.0738496638189075 0.10475316544260069 1.2229201985154274 0.028596132236349957 0.02443639110025773 1.2980195098309242e-07 6.886718779840552 0.37451613340313994 YSCPES(ph)PSQELGGPLPSPGPR ddPTM_PC-9_Lapatinib_30min_R1 1 YSCPESPSQELGGPLPSPGPR 21 0 A0A494BZV2;A0A1W2PPU9 A0A494BZV2 1 YSCPES(0.952)PS(0.048)QELGGPLPSPGPR 154.72 1.614e-05 20555000.0 59161.0 56922.0 75780.0 69629.0 68050.0 58994.0 50566.0 46005.0 60646.0 43389.0 True False 58317.353291201296 56790.200606277234 69549.66091925939 74749.74893553476 64047.43279144765 56470.964141730794 53184.060058661766 48142.56024950952 53815.40884930823 50888.73083779164 1.145977750498209 1.1159681067169192 1.3667006383191134 1.4688860913784698 1.2585779157196808 1.1096948815982968 1.045104862767879 0.9460357815360818 1.0575113185833895 1.0 15.635058590576556 -6.9371971334239815 2.5205457934524005 1.0087542370365947 1.2799559228738884 0.6117835138081014 0.09789802528319842 0.2191654222745672 2.8231210107704134 0.04486891003274126 0.03728427659966281 1.155587582873483e-07 6.9371971334239815 0.27120168583729365 YSCPESPS(ph)QELGGPLPSPGPR ddPTM_PC-9_Lapatinib_30min_R1 1 YSCPESPSQELGGPLPSPGPR 21 0 A0A494BZV2;A0A1W2PPU9 A0A494BZV2 1 YSCPES(0.321)PS(0.679)QELGGPLPSPGPR 129.01 1.997e-05 21574000.0 57460.0 65550.0 65801.0 65922.0 59729.0 49441.0 51253.0 50938.0 59288.0 51580.0 True False 56640.60986312653 65398.22300237997 60391.09577920541 70770.12378934528 56215.85765173216 47326.523682600135 53906.62955714495 53304.765438311435 52610.36110968223 60495.53427397017 0.9362775375553246 1.0810421593469473 0.9982736164575094 1.1698404624189926 0.9292563215847248 0.7823143352742261 0.8910844445643608 0.8811355429461385 0.8696569381703808 1.0 15.884541027414569 -6.509114664651255 24.36139206123484 0.8753535719561674 1.0459196373591255 0.5123727442605829 0.07442302772454634 340.57481670159063 602793.2713644671 0.022324723412819915 0.024276057250753207 3.096601610674624e-07 6.509114664651255 0.17056606540295816 YSCPESPSQELGGPLPS(ph)PGPR ddPTM_PC-9_AZD4547_30min_R2 2 YSCPESPSQELGGPLPSPGPR 21 0 A0A494BZV2;A0A1W2PPU9 A0A494BZV2 1 YSCPESPSQELGGPLPS(1)PGPR;YSCPESPSQELGGPLPS(1)PGPR 252.37 1.0519999999999999e-62 52699000.0 40918.0 43543.0 61886.0 71222.0 63812.0 58700.0 48814.0 63372.0 46697.0 51467.0 True False 53929.07285272796 57617.42322022574 61065.35120440597 54802.86826893093 54952.8052752978 55029.47972052924 53158.35143475183 53579.313543688535 49165.30808618506 49665.155995335575 1.085853286311893 1.1601176330874108 1.2295411134949636 1.1034470177457587 1.1064659754709887 1.1080098032048358 1.0703349334036991 1.0788109383713718 0.9899356420183708 1.0 15.599946422432954 -7.5635604460905395 0.6482954511642961 0.9929349136651062 1.1525579064210096 0.6523621314303563 0.03897696543651941 0.47395215487034786 0.3942016436650799 0.0373157195773353 0.021614178810120097 2.7317412074838873e-08 7.5635604460905395 0.15962299275590341 YSCPESPSQELGGPLPS(ph)PGPR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YSCPESPSQELGGPLPSPGPR 21 0 A0A494BZV2;A0A1W2PPU9 A0A494BZV2 1 YSCPESPSQELGGPLPS(1)PGPR;YSCPESPSQELGGPLPS(1)PGPR;YSCPESPSQELGGPLPS(1)PGPR;YSCPESPSQELGGPLPS(1)PGPR 178.1 1.0715e-12 28888600.0 20940.5 30078.8 49038.8 57977.7 99586.9 104912.9 114052.1 109869.0 102440.3 97015.1 True False 24485.31305627239 33064.82448013602 50208.07097268463 54729.397435239516 80073.56183554341 99411.08283539499 103248.25942230216 106985.05516582813 103938.29558949269 114603.16965889098 0.21365301788032007 0.2885157939222044 0.43810368528310123 0.47755570459471647 0.6987028550246669 0.8674374638265742 0.9009197540488104 0.9335261449073556 0.9069408455181335 1.0 16.80628742069503 -6.140679875428197 0.7557147744980528 0.9635444089817299 0.19465031103205788 0.985473198421575 0.033491498379035145 0.08450715865183876 0.10056112954891787 0.01930120617390022 0.039756915300221504 7.233027637936567e-07 6.140679875428197 -0.768894097949672 down YSCPESPSQELGGPLPS(ph)PGPR ddPTM_PC-9_Lapatinib_30min_R1 2 YSCPESPSQELGGPLPSPGPR 21 0 A0A494BZV2;A0A1W2PPU9 A0A494BZV2 1 YSCPES(0.001)PS(0.004)QELGGPLPS(0.996)PGPR;YSCPESPSQELGGPLPS(0.999)PGPR 206.92 1.337e-24 35201000.0 23111.0 20871.7 22098.0 23323.6 41396.0 56066.0 45840.0 49745.0 58085.0 42925.0 True False 22781.432901961653 20823.37286100343 20281.187740746795 25038.89534924876 38961.168667667334 53668.18787622945 48213.370903157396 52056.33430305084 51542.8556378338 50344.52905603275 0.4525105970622198 0.41361739302054673 0.4028478986897289 0.49735087046659676 0.7738908159078041 1.0660182721442784 0.9576685254021663 1.03400181269176 1.0238025184517534 1.0 15.619547388514851 -6.407306133856141 2.180904620883248 1.0166135714344546 0.423169830682403 0.9831163631453184 0.03549464117568091 0.034553582363937276 0.3238005102566984 0.012041003762262003 0.014010531627980561 3.9146583585306925e-07 6.407306133856141 -0.5934437407520516 down YSDEQLNS(ph)GRQSPSQNER ddPTM_PC-9_AZD4547_30min_R2 1 YSDEQLNSGRQSPSQNER 18 1 P25054-2;P25054-3;P25054;A0A2Q2SV78;E9PFT7 P25054-2 APC Adenomatous polyposis coli protein 1 YSDEQLNS(0.719)GRQS(0.258)PS(0.022)QNER 67.994 0.0058628 22748000.0 15737.0 6073.0 33572.0 37811.0 30780.0 22996.0 12222.0 34219.0 21078.0 24368.0 True False 20741.03865006549 8035.978486012243 33126.81334444487 29094.258124126638 26506.728301474137 21558.056484723857 13309.734322848708 28931.23982439373 22192.14004841015 23514.883737041946 0.882038749670408 0.3417400900585158 1.408759393194944 1.2372699116643198 1.1272319522345446 0.9167834604584676 0.5660131885696921 1.2303373534787945 0.9437486613404711 1.0 14.521286578749057 -5.254199826022777 24.998120632189334 1.0488595600714143 0.611889447077802 0.3370581808616887 0.2478072899666506 658.4722194901086 2273685.5552009107 0.06546273823998096 0.16562198637422493 5.569294375902165e-06 5.254199826022777 -0.4369701129936123 YSDEQLNSGRQS(ph)PSQNER ddPTM_PC-9_AZD4547_30min_R2 1 YSDEQLNSGRQSPSQNER 18 1 P25054-2;P25054-3;P25054;A0A2Q2SV78;E9PFT7 P25054-2 APC Adenomatous polyposis coli protein 1 YSDEQLNS(0.059)GRQS(0.857)PS(0.084)QNER 88.637 0.0073420000000000004 3800700.0 7398.2 9427.8 11506.0 18217.0 14773.0 9879.3 7793.7 14472.0 8131.5 11975.0 True False 9750.67370788044 12475.151979322602 11353.422922113152 14017.352099844362 12722.023950541821 9261.545809250845 8487.32420160251 12235.684933476306 8561.314489213732 11555.758894906325 0.8437934536846775 1.0795614630573105 0.9824904643101925 1.213018740467412 1.1009250077162458 0.8014658226672808 0.7344670548070752 1.0588387179720138 0.7408699477961143 1.0 13.49632438777267 -6.759228340314158 24.999876707587134 0.8625143919541577 1.051913237514181 0.3143019099710809 0.13023859816883962 69.59463670850648 786897.6282454006 0.04366759762140592 0.0416717083917133 1.7408913190682198e-07 6.759228340314158 0.1893988455600234 YSDVEVPASVTGY(ph)SFASDGDSGTCSPLRHSFQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSDVEVPASVTGYSFASDGDSGTCSPLRHSFQK 33 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5 P35611 ADD1 Alpha-adducin 1 YSDVEVPAS(0.002)VT(0.164)GY(0.447)S(0.164)FAS(0.164)DGDS(0.024)GT(0.009)CS(0.019)PLRHS(0.008)FQK 52.577 0.004522 4040000.0 11491.0 12223.0 17296.0 23893.0 28539.0 22686.0 23050.0 17075.0 19495.0 15249.0 True False 13436.199342404718 13436.418661007176 17708.402235445268 22554.35267215115 22946.987818925692 21496.306223579457 20866.537132451427 16626.79934245796 19780.07749408348 18013.52298898241 0.7458951450320231 0.7459073202518617 0.9830615724795331 1.2520789345840924 1.2738756229395398 1.193342703519307 1.1583817971206412 0.9230176325101642 1.0980682405202773 1.0 14.136792743008398 -5.416195801205054 3.2913056530094313 1.1349140563229496 0.7443421584456628 0.6873935597363299 0.10187829924301961 0.14751949069215423 2.9663670235213466 0.030691515621302935 0.07132257254071195 3.835342904801541e-06 5.416195801205054 -0.39057189787728686 YSDVEVPASVTGYSFASDGDS(ph)GTCSPLRHSFQK ddPTM_PC-9_AZD4547_30min_R2 1 YSDVEVPASVTGYSFASDGDSGTCSPLRHSFQK 33 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5 P35611 ADD1 Alpha-adducin 1 YSDVEVPAS(0.043)VT(0.04)GY(0.04)S(0.04)FAS(0.054)DGDS(0.276)GT(0.093)CS(0.206)PLRHS(0.206)FQK 50.47 0.0028247 20961000.0 55750.0 61915.0 130700.0 253090.0 187940.0 166920.0 84257.0 173490.0 121300.0 150890.0 True False 73477.34032796294 81927.81293618439 128966.83260213693 194744.01070152107 161847.77508054095 156482.46601278952 91755.70977256283 146681.1069035937 127711.67036114211 145607.38702734152 0.5046264604292754 0.5626624761887963 0.8857162760425067 1.3374596899053814 1.1115354679783511 1.0746876872627755 0.6301583432393669 1.0073740755752354 0.877096093601082 1.0 17.15172402336198 -5.309109961926896 3.7714907063256264 1.0036458347388184 0.5223678767028419 0.5446847565866623 0.16960993361756327 0.1745116224221613 5.1655307862891755 0.04901250659839415 0.1200966612838979 4.90783595635838e-06 5.309109961926896 -0.4812779580359765 YSDVEVPASVTGYSFASDGDS(ph)GTCSPLRHSFQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YSDVEVPASVTGYSFASDGDSGTCSPLRHSFQK 33 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5 P35611 ADD1 Alpha-adducin 1 YSDVEVPASVTGY(0.001)S(0.004)FAS(0.03)DGDS(0.352)GT(0.101)CS(0.256)PLRHS(0.256)FQK;YSDVEVPASVT(0.002)GY(0.003)S(0.004)FAS(0.019)DGDS(0.365)GT(0.168)CS(0.219)PLRHS(0.219)FQK 64.422 1.721e-05 21661300.0 38615.0 42435.0 71671.0 91473.0 99540.0 87623.0 80094.0 69057.0 76837.0 62146.0 True False 45151.756818985144 46647.66635685506 73379.90845378108 86348.06436946726 80035.85155386901 83027.8956285242 72506.91648965587 67244.32692193968 77960.5957636775 73412.5778525346 0.615041156975613 0.6354179041438541 0.9995549890807658 1.1762025921895354 1.0902198764173454 1.1309764356089511 0.9876634033380771 0.9159782817736598 1.061951480852213 1.0 16.163739642221493 -5.281653604021014 4.281662451108743 1.0527291864442574 0.616418172223112 0.8531729983536414 0.06997930876149783 0.07209417463895407 3.268977958407287 0.020451156627878313 0.05014201237752791 5.228130216595192e-06 5.281653604021014 -0.4363110142211454 YSDVEVPASVTGYSFASDGDS(ph)GTCSPLRHSFQK ddPTM_PC-9_Lapatinib_30min_R1 3 YSDVEVPASVTGYSFASDGDSGTCSPLRHSFQK 33 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5 P35611 ADD1 Alpha-adducin 1 YSDVEVPAS(0.038)VT(0.034)GY(0.033)S(0.033)FAS(0.033)DGDS(0.219)GT(0.219)CS(0.196)PLRHS(0.196)FQK;YSDVEVPASVTGY(0.001)S(0.008)FAS(0.081)DGDS(0.376)GT(0.106)CS(0.214)PLRHS(0.214)FQK;YSDVEVPASVTGYSFAS(0.002)DGDS(0.307)GT(0.077)CS(0.307)PLRHS(0.307)FQK 84.57600000000001 9.7445e-12 20260800.0 96526.0 66564.0 153845.0 95996.0 110600.0 135247.0 94075.0 98019.0 159006.0 84749.0 True False 95149.5215392997 66409.87514767988 141196.4579588739 103055.86607326841 104094.72544796632 129462.80108615565 98945.74318748974 102573.3205759521 141097.06987259016 99397.7517290557 0.9572602989921133 0.6681225077273766 1.4205196345260969 1.0368027875940717 1.0472543255476634 1.302472126724285 0.9954525275098971 1.0319480953206321 1.4195197317661765 1.0 16.600925599485656 -5.24766364644375 24.99792011225713 1.1491370625520674 0.8126914031243564 0.3906875961769447 0.17165677475745372 780.1669508098119 1415712.0029965516 0.041572894732452924 0.1087559376961111 5.653746781921484e-06 5.24766364644375 -0.336445659427711 YSDVEVPASVTGYSFASDGDSGTCS(ph)PLR ddPTM_PC-9_AZD4547_30min_R2 1 YSDVEVPASVTGYSFASDGDSGTCSPLR 28 0 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5 P35611 ADD1 Alpha-adducin 1 YSDVEVPASVTGYSFAS(0.023)DGDS(0.021)GT(0.111)CS(0.845)PLR 80.72 6.3011000000000005e-06 2855700.0 27784.0 22531.0 42745.0 60642.0 47744.0 46962.0 30252.0 44642.0 34431.0 40746.0 True False 36618.73405689903 29813.705132280887 42178.17337091316 46661.92380956039 41115.56972142886 44025.45871610719 32944.36939411053 37743.60467110622 36250.95236772037 39319.494942117155 0.9313124217593854 0.7582423216821608 1.0727038440601617 1.1867376190424657 1.0456789890601528 1.1196852548822858 0.8378634934809934 0.9599208923377367 0.921958748989171 1.0 15.26295716996694 -10.60910868205929 17.721109311718354 0.9999999999611432 0.9847983285420338 0.0014031428497588427 0.12278180086743973 0.0 0.0 0.1288292354606378 0.031245679145398705 2.4597519749521155e-11 10.60910868205929 -0.015201671419109442 YSDVEVPASVTGYSFASDGDSGTCS(ph)PLRHSFQK ddPTM_PC-9_AZD4547_30min_R2 1 YSDVEVPASVTGYSFASDGDSGTCSPLRHSFQK 33 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5 P35611 ADD1 Alpha-adducin 1 YSDVEVPASVTGYS(0.001)FAS(0.009)DGDS(0.177)GT(0.177)CS(0.578)PLRHS(0.057)FQK 57.711000000000006 0.00037039999999999995 5876500.0 10758.0 9672.3 21910.0 39140.0 32517.0 27369.0 18327.0 27745.0 17585.0 23426.0 True False 14178.820219699097 12798.681822864519 21619.459084260325 30116.877706971944 28002.57583427663 25657.612103426993 19958.0674958966 23457.64776667361 18514.507199510983 22605.862870319455 0.6272187131735321 0.5661664806287332 0.9563651344910954 1.3322595947670786 1.2387306777412523 1.1349981308218213 0.8828712980516529 1.0376798223204526 0.8190135145789879 1.0 14.464409366216396 -5.349334137406567 4.2324132155191 1.0721320030895554 0.5955190983299562 0.6140450742500543 0.14519404855400583 0.14643502346245257 4.677814289189476 0.042301497623165464 0.09550787799349546 4.4736897507576095e-06 5.349334137406567 -0.47661290475959917 YSDVEVPASVTGYSFASDGDSGTCSPLRHS(ph)FQK ddPTM_PC-9_AZD4547_30min_R2 1 YSDVEVPASVTGYSFASDGDSGTCSPLRHSFQK 33 1 P35611;P35611-3;E7EV99;E7ENY0;P35611-2;P35611-6;P35611-4;H0Y9H2;P35611-5 P35611 ADD1 Alpha-adducin 1 YSDVEVPASVTGYS(0.001)FAS(0.006)DGDS(0.108)GT(0.078)CS(0.184)PLRHS(0.623)FQK 69.72 7.7204e-06 21034000.0 33810.0 28779.0 74678.0 142570.0 108060.0 92019.0 51236.0 97542.0 66062.0 77219.0 True False 44560.87670831253 38081.24894598159 73687.72092626162 109702.68918454247 93057.73425137409 86265.03738336235 55795.90474271609 82469.12519217441 69553.90245175408 74515.58631363447 0.5980074627710339 0.5110507858812041 0.9888900372616223 1.4722113132520525 1.2488358322740174 1.1576777644917762 0.7487816643872646 1.1067365805197273 0.9334141471960407 1.0 16.185254603050552 -5.333625439524816 4.627673699334052 1.1023042253274515 0.5533731787427107 0.5747645054756458 0.1825883248116746 0.14978360599120646 6.064362118747546 0.05249095335471009 0.11711125768939762 4.6384679535928644e-06 5.333625439524816 -0.5489310465847408 YSEEANNLIEECEQAER ddPTM_PC-9_Lapatinib_30min_R1 2 YSEEANNLIEECEQAER 17 0 G3V5B3;G3V3E6;Q96HE7 G3V5B3 ERO1L ERO1-like protein alpha 0 ; 184.0 5.4313e-33 1247300.0 2574.2 4610.8 3745.5 3141.29 3854.0 2788.48 4028.53 1946.65 5930.9 2610.53 False True 2537.491435949535 4600.123975886706 3437.559448048109 3372.310945636248 3627.315297255533 2669.2232106643633 4237.107571651323 2037.098465595214 5262.899586854239 3061.756632187424 0.8287698013857698 1.502445990490178 1.122740916737134 1.1014301104745066 1.184717053969131 0.8717947019706065 1.3838812422606521 0.6653365078660223 1.7189150605658172 1.0 11.58014389751612 -4.516960736453399 19.8873672628631 1.156321208171723 0.3994715325000651 0.11016572410258518 0.2897416792135534 13015455.535204172 464479673.20519227 0.06553748630915722 253202215.66447943 3.041159957394746e-05 4.516960736453399 -0.7568496756716578 YSEEGLS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 2 YSEEGLSPSK 10 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 YSEEGLS(0.968)PS(0.032)K;YSEEGLS(0.995)PS(0.005)K 129.74 0.00023622 42623000.0 109153.0 85471.0 86500.0 111186.0 130134.0 131855.0 117266.0 106219.0 107288.0 99077.0 True False 143861.38347655805 113097.82927349774 85352.95348190397 85553.78550657608 112067.14037634942 123610.08600596907 127702.44682565701 89805.2942197982 112959.02464720681 95608.34438669168 1.5046948506367297 1.182928435786621 0.892735399084944 0.8948359691341423 1.1721481121259614 1.2928796832421159 1.3356830687200218 0.9393039362398871 1.1814766312691247 1.0 16.544848917001787 -1.5229604169465594 0.015025270647116206 1.7177283400043804e-07 2.499145532455959 0.07248078461125973 0.1878338027847931 23063.300042221043 26.855801895382797 1785.783904812249 2783.193756036361 0.029994358851607547 1.5229604169465594 2.4991453606831247 YSEEGLS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YSEEGLSPSK 10 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 YSEEGLS(0.998)PS(0.002)K;YSEEGLS(0.992)PS(0.007)K;YSEEGLS(0.999)PS(0.001)K;YSEEGLS(0.998)PS(0.002)K 132.56 0.00014227 71994000.0 199296.0 218474.0 209744.0 219010.0 246781.0 177741.0 239044.0 240134.0 205474.0 174784.0 True False 233032.87652457526 240162.65487563485 214745.09241854923 206739.57974000034 198426.03458223093 168419.94906485226 216400.0217913107 233830.73694300425 208478.66853138272 206470.95561061773 1.128647251306622 1.1631788798835032 1.0400740955717551 1.0013010262319375 0.9610360643481562 0.8157077036175218 1.0480894087564456 1.1325115256597356 1.0097239484111815 1.0 17.655579325604087 -5.416943312223386 3.0644982881382314 0.9948115906396273 1.146836971586343 0.3839174953297554 0.07496486259485279 0.2957046373022533 5.23583720342827 0.022993052898771592 0.05475923495341448 3.828747160906613e-06 5.416943312223386 0.15202538094671558 YSEEGLS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 3 YSEEGLSPSK 10 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 YSEEGLS(0.962)PS(0.038)K;YSEEGLS(0.774)PS(0.226)K;YS(0.007)EEGLS(0.989)PS(0.004)K 111.5 0.0015869999999999999 67733000.0 169460.0 164214.0 161646.0 206558.0 208329.0 190857.0 168917.0 174012.0 194612.0 176577.0 True False 167043.46932484224 163833.7725722781 148356.08985160422 221748.964377288 196075.49781057306 182694.4910193972 177662.69574277126 182097.23278203752 172692.74720478823 207098.09917593672 0.8065910309632213 0.79109259439941 0.7163565983556942 1.0707436005431652 0.9467759414054322 0.8821640166971892 0.8578673413696613 0.8792800779274168 0.8338693010314885 1.0 17.65995478645958 -5.732101454111323 24.999999788800373 0.9157579765202496 0.7733213042488374 0.49687318170543104 0.07018790767082844 196.80249711883008 167701.68441183114 0.01993728041687221 0.034525723739602845 1.853098676535397e-06 5.732101454111323 -0.1424366722714122 YSEEGLS(ph)PSKR ddPTM_PC-9_AZD4547_30min_R2 2 YSEEGLSPSKR 11 1 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 YS(0.183)EEGLS(0.77)PS(0.047)KR;YSEEGLS(0.98)PS(0.02)KR 148.13 0.00014543 39948000.0 80746.0 74361.0 86781.0 103838.0 90211.0 90389.0 90475.0 98545.0 86636.0 102155.0 True False 106421.5483788646 98396.73904138923 85630.2272383019 79899.75338110777 77686.75980520734 84736.96154103779 98527.09972670072 83317.13458882159 91215.40208910055 98578.58454356184 1.0795605239374984 0.9981553244752439 0.8686493890613933 0.810518367159148 0.7880693374216343 0.8595879311250666 0.9994777281790005 0.8451849351925294 0.9253064700760893 1.0 16.588986645538867 -5.0680456141336006 2.9704949707429495 0.8783731303381994 1.0735782135839906 0.45792862064209816 0.06808803564783839 0.23607374371459486 3.866508853035512 0.0185001228157737 0.07812370543816452 8.549769095813529e-06 5.0680456141336006 0.19520508324579122 YSEEGLS(ph)PSKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YSEEGLSPSKR 11 1 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 YS(0.008)EEGLS(0.676)PS(0.316)KR;YSEEGLS(0.881)PS(0.118)KR 113.61 0.0022651999999999998 28226000.0 64881.0 58737.0 64294.0 68518.0 70980.0 60048.0 77035.0 68573.0 63411.0 52289.0 True False 75864.07184183798 64568.02118069033 65827.01279635273 64679.1585983531 57071.978534193375 56898.97717153749 69737.68711489804 66773.03140909912 64338.26591317399 61768.58178050377 1.2281983761813229 1.0453214129172406 1.0657038076456198 1.0471206677237974 0.9239645283908267 0.921163729705329 1.1290155141122178 1.0810193383811009 1.0416017991444526 1.0 15.914585586042572 YSEEGLS(ph)PSKR ddPTM_PC-9_Lapatinib_30min_R1 2 YSEEGLSPSKR 11 1 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 YSEEGLS(0.968)PS(0.032)KR;YSEEGLS(0.848)PS(0.152)KR 118.76 0.0015154 39200000.0 152528.0 121962.0 131666.0 137244.0 135874.0 121318.0 113331.0 104462.0 142134.0 120092.0 True False 150352.92274979025 121679.60448232302 120840.92972545802 147337.3815925626 127882.15845856207 116129.51194607078 119198.72464715813 109315.68587727977 126125.37218262664 140849.74218746834 1.067470344032816 0.8638965367815141 0.8579421435122049 1.0460607119639547 0.9079332093370348 0.8244921867979326 0.8462828741887712 0.7761156263373394 0.8954604404937864 1.0 17.10379739743115 -6.536214367098865 9.55000209096354 0.8544457173992751 0.9488582091804109 0.19556144139320297 0.08304805032755237 0.32951715412369803 208.84504905677207 0.02667077649106435 0.027075891745151036 2.9092807470275997e-07 6.536214367098865 0.09441249178113575 YSESNFS(ph)VDDQDLSR ddPTM_PC-9_AZD4547_30min_R2 2 YSESNFSVDDQDLSR 15 0 Q5TH69 Q5TH69 ARFGEF3 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 1 YSES(0.004)NFS(0.996)VDDQDLSR;YSESNFS(1)VDDQDLSR 191.36 9.7301e-08 1386800.0 3734.7 2518.1000000000004 7021.7 11822.400000000001 8427.400000000001 8769.8 7379.6 9794.4 6764.0 8345.7 True False 4922.256913414223 3332.0265808706445 6928.587670102726 9096.92833425921 7257.400977512769 8221.423019643906 8036.37010382051 8280.900532921534 7121.531231020318 8053.5195832333775 0.6111932630873426 0.4137354539756246 0.8603179763202355 1.1295593485856923 0.9011464990563818 1.0208484544769825 0.997870560909969 1.0282337364847962 0.8842756458737164 1.0 12.975403698396095 -5.406964595522884 4.357099463253721 0.9934268552396484 0.5170431018156784 0.8511132758539464 0.0793288499953216 0.06944880288494984 2.1335178677398035 0.019686438072678877 0.04300351989481713 3.917738139208141e-06 5.406964595522884 -0.47638375342397 YSESNFS(ph)VDDQDLSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSESNFSVDDQDLSR 15 0 Q5TH69 Q5TH69 ARFGEF3 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 1 YSESNFS(1)VDDQDLSR 194.05 1.4246e-09 1414300.0 2812.0 2684.3 3457.1 3486.0 2835.9 4476.8 3289.7 3821.2 3292.5 1956.0 True False 3288.0160604683697 2950.779564079323 3539.53037512476 3290.690721764488 2280.2257526784874 4242.028727044011 2978.0758006345104 3720.8975488960687 3340.6465837019646 2310.607316312519 1.4230094561094397 1.2770580025637805 1.531861493788339 1.4241670138117961 0.9868512648516508 1.835893402178711 1.288871449341379 1.6103547853532385 1.4457872439499058 1.0 11.174056381791031 -6.757089955213675 24.999968453048627 1.465121643206469 1.3423294518415358 0.03903608356597266 0.2420939492342312 359.9643698285737 2069032.2877227075 0.07705270234663843 0.0745237532959774 1.7494842812293252e-07 6.757089955213675 -0.12279219136493325 YSESNFS(ph)VDDQDLSR ddPTM_PC-9_Lapatinib_30min_R1 2 YSESNFSVDDQDLSR 15 0 Q5TH69 Q5TH69 ARFGEF3 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 1 YSES(0.014)NFS(0.986)VDDQDLSR;YSES(0.004)NFS(0.996)VDDQDLSR 148.97 0.00013112 1213900.0 10540.9 8712.599999999999 11397.5 9540.3 7823.8 9589.1 9558.4 5516.400000000001 14254.800000000001 3648.8999999999996 True False 10390.58483303568 8692.426510000541 10460.441545622303 10241.925487507844 7363.619466182627 9178.996546283877 10053.287182389606 5772.7120826082955 12649.274314301336 4279.607503146372 2.4279293896453145 2.0311270376103088 2.444252548377807 2.3931927121769854 1.7206296280135234 2.144822051913749 2.34911429961706 1.3488882049029476 2.955708976816583 1.0 12.063262773057208 -11.330945011654045 2.8122786856708353 0.661707155456244 2.172912383557499 0.42681278808889345 0.41658947851254075 38295739.08211823 40642728.24204663 89981091.56344093 0.10268434228414458 4.667184702938145e-12 11.330945011654045 1.5112052281012547 YSGLTAS(ph)SK ddPTM_PC-9_AZD4547_30min_R2 1 YSGLTASSK 9 0 Q96AT1 Q96AT1 KIAA1143 Uncharacterized protein KIAA1143 1 YSGLT(0.002)AS(0.821)S(0.177)K 81.625 0.016959000000000002 3792000.0 16295.0 17623.0 16790.0 13362.0 19921.0 23618.0 19195.0 20347.0 20795.0 25484.0 True False 21476.471042944475 23319.290113451945 16567.353629608897 10281.597340842085 17155.313011490118 22141.162726396244 20903.317814357775 17202.83867754579 21894.181246166103 24591.812916725903 0.8733179255904897 0.9482542093345032 0.6736938706271939 0.41809025530806426 0.6976026155364123 0.9003469081914302 0.850011257207498 0.6995351963598191 0.8903036681478237 1.0 14.585890474367966 -6.752150974785275 24.944125060445806 0.8481335974006955 0.7151619228431191 0.18854614813610115 0.14808032174354227 410.66242168468807 1102837.4409909432 0.05460726293791564 0.05388942450139711 1.7694937182315612e-07 6.752150974785275 -0.1329716745575764 YSGLTAS(ph)SK ddPTM_PC-9_Lapatinib_30min_R1 1 YSGLTASSK 9 0 Q96AT1 Q96AT1 KIAA1143 Uncharacterized protein KIAA1143 1 YSGLT(0.003)AS(0.975)S(0.022)K 73.632 0.029071 3033500.0 19019.0 25523.0 28473.0 25648.0 26812.0 25460.0 16522.0 19302.0 22250.0 18257.0 True False 18747.785572342567 25463.90306162845 26132.05984895842 27534.23947921984 25234.970874420178 24371.135150158778 17377.42831723312 20198.84138541536 19743.970697112898 21412.698124076658 0.875545223853054 1.1891963784328783 1.2204001428281128 1.2858836994605578 1.1785049566474632 1.1381627391811788 0.811547812262564 0.9433113598469673 0.9220683251921706 1.0 14.386178974664352 -7.1777910789064086 6.67074052911371 0.9150989399616017 1.1623136707601638 0.5071483633501632 0.10998980078922681 0.20095293080743776 13.475702711611772 0.04327170716341787 0.0334012143200428 6.640624465244278e-08 7.1777910789064086 0.24721473079856204 YSGSEGSTQTLTK ddPTM_PC-9_Lapatinib_30min_R1 1 YSGSEGSTQTLTK 13 0 P25815 P25815 S100P Protein S100-P 0 134.08 0.00020731 5034500.0 24718.0 30594.0 35610.0 27605.0 23411.0 29881.0 25736.0 17930.0 16441.0 18003.0 False True 24365.516787273948 30523.161472689746 32682.28325857514 29635.16378758048 22034.01100779689 28603.05928601311 27068.484152784888 18763.093256683103 14589.241448594737 21114.79456251038 1.1539547171600368 1.4455817404391922 1.5478380886832308 1.4035260300471093 1.0435342357968564 1.354645398103861 1.2819676778122848 0.8886230553243102 0.6909487755328743 1.0 14.365966589980669 -7.766938204713467 4.076179073696418 0.8281268410341502 1.3304267955157676 0.6602065738571299 0.15116160730147715 0.1270785634505528 4.756525052174632 0.08783509700636273 0.0430769331604606 1.7102586486094296e-08 7.766938204713467 0.5022999544816174 YSHPGETDGTR ddPTM_PC-9_AZD4547_30min_R2 2 YSHPGETDGTR 11 0 Q9UKK3 Q9UKK3 PARP4 Poly [ADP-ribose] polymerase 4 0 ; 110.84 0.0013649 0.0 8798.599999999999 5877.1 14515.4 20069.0 15760.400000000001 12659.2 9911.4 15276.599999999999 9625.8 12441.5 False True 11596.371777750915 7776.75764204554 14322.91631180613 15442.402112959131 13572.340504306461 11867.61822279597 10793.495399074014 12915.952491344955 10134.600136539826 12005.926871897875 0.9658872573090879 0.6477432125834867 1.1929871358230246 1.2862315652700644 1.130470029438133 0.9884799690538145 0.8990139215605433 1.075798031185511 0.8441330889880531 1.0 13.55145916519798 -10.604547792214845 14.563453663438427 1.000019103868146 1.0092046028985215 0.0 0.17378457254387336 0.0 0.0 0.17994477576272258 0.04364301866163471 2.4857200065239694e-11 10.604547792214845 0.009185499030375466 YSHPGETDGTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSHPGETDGTR 11 0 Q9UKK3 Q9UKK3 PARP4 Poly [ADP-ribose] polymerase 4 0 70.41199999999999 0.034727 0.0 5466.9 4243.9 5363.9 4262.6 5115.9 5543.4 5132.4 3505.3 4316.0 2681.3 False True 6392.338193803179 4665.206345041994 5491.795718704032 4023.780341535657 4113.476119795434 5252.694345402025 4646.221916641814 3413.2895891723524 4379.113334930199 3167.3984648408773 2.0181667272874413 1.4728826817425267 1.7338505968430236 1.2703739002846939 1.2986923386673062 1.6583623449050033 1.4668889841983392 1.0776318884601808 1.382558394070004 1.0 11.629082657266249 -1.5228787452803376 0.15367307663369495 0.9986039184473678 4.047739981990187 0.564331368480363 0.19209894336371722 54.1384936165521 0.5441374013593573 0.6490561298646781 36.990309752156 0.029999999999999995 1.5228787452803376 3.049136063542819 YSHS(ph)YLSDSDTEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSHSYLSDSDTEAK 14 0 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614;Q92614-5;Q92614-2 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 YS(0.024)HS(0.812)YLS(0.163)DS(0.002)DTEAK 180.3 4.7666e-05 3707300.0 10165.0 12568.0 9658.9 15804.0 14149.0 16060.0 11466.0 9988.6 12310.0 11636.0 True False 11885.733732098508 13815.667980981594 9889.204807582231 14918.55311725931 11376.605019446359 15217.785327985812 10379.857473348722 9726.409833796522 12490.010461768017 13745.514689474689 0.8646990673401073 1.005103722420858 0.7194495827176746 1.0853397238506353 0.8276594421129776 1.107109167737348 0.7551450569760665 0.7076060848593976 0.9086608063743117 1.0 13.746673307939105 YSHSGSSS(ph)PDTK ddPTM_PC-9_AZD4547_30min_R2 7 YSHSGSSSPDTK 12 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 YSHSGS(0.001)S(0.001)S(0.999)PDTK;YSHSGS(0.004)S(0.004)S(0.991)PDTK;YSHSGSS(0.001)S(0.999)PDTK;Y(0.001)S(0.002)HS(0.001)GS(0.102)S(0.144)S(0.751)PDTK;YS(0.001)HSGS(0.003)S(0.096)S(0.899)PDT(0.001)K;YSHS(0.003)GS(0.102)S(0.018)S(0.876)PDTK;YSHSGS(0.282)S(0.147)S(0.571)PDTK 225.79 2.1476999999999998e-15 247464600.0 139992.3 99292.5 247618.0 339656.0 296186.0 286046.0 213288.0 233954.0 263895.0 315585.0 True False 184506.93937926972 131386.858854334 244334.42352927284 261353.5568328885 255065.68644250918 268159.4984009962 232270.21880639455 197801.78502809006 277843.9509476799 304536.4652065983 0.6058615649002813 0.43143227122308925 0.8023158191040136 0.8582011899809293 0.83755384193309 0.8805497174831793 0.7627008432268427 0.6495175705605595 0.9123503510792703 1.0 18.216255461264467 -5.302484109296346 8.371468695060845 0.8252971835735727 0.5188957610664583 0.6352426605110412 0.09639547108292298 0.18426259590157149 35.58983416324465 0.024684122041141454 0.05209022159033878 4.983286893328749e-06 5.302484109296346 -0.30640142250711444 YSHSGSSS(ph)PDTK ddPTM_PC-9_LapatinibAZD4547_30min_R1 8 YSHSGSSSPDTK 12 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 YSHSGS(0.003)S(0.062)S(0.933)PDT(0.002)K;YSHSGSSS(1)PDTK;YSHSGSS(0.001)S(0.999)PDTK;YSHSGSS(0.043)S(0.957)PDTK;YSHSGS(0.005)S(0.005)S(0.99)PDTK;YSHS(0.003)GS(0.007)S(0.038)S(0.95)PDT(0.002)K;YSHSGS(0.023)S(0.005)S(0.972)PDTK;YSHSGSSS(0.999)PDTK 238.07 8.178099999999999e-22 173399500.0 102921.70000000001 133466.0 183865.5 197853.3 273191.0 286569.0 208647.4 251972.0 265141.0 197289.0 True False 120344.311013765 146715.62243393468 188249.55083379167 186768.22105005366 219661.1846680023 271540.8171641071 188882.80779563746 245358.00198640276 269018.1855275083 233055.9339611357 0.5163752279048752 0.6295296581394958 0.8077440794328115 0.8013879667238982 0.9425256029079822 1.1651315310829593 0.810461268182665 1.0527859034360332 1.1543073843053044 1.0 17.830316721007364 -5.121379242864719 0.5808709296106443 1.0491654120883869 0.28226708804620093 0.7697373650149067 0.09778486667855234 1.3070446511458296 0.44066130764889605 0.055954337409207425 0.6393261462931049 7.561722875216747e-06 5.121379242864719 -0.7668983240421859 YSHSGSSS(ph)PDTK ddPTM_PC-9_Lapatinib_30min_R1 9 YSHSGSSSPDTK 12 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 YSHSGS(0.001)S(0.001)S(0.999)PDTK;YSHSGS(0.001)S(0.001)S(0.999)PDTK;YSHSGSS(0.044)S(0.956)PDTK;YSHSGS(0.007)S(0.007)S(0.985)PDT(0.001)K;YSHSGSS(0.048)S(0.944)PDT(0.008)K;YSHSGS(0.004)S(0.004)S(0.991)PDT(0.001)K;YSHSGS(0.023)S(0.023)S(0.954)PDTK;YSHS(0.022)GS(0.075)S(0.013)S(0.89)PDTK;YSHSGS(0.001)S(0.002)S(0.997)PDTK 215.02 9.3576e-11 262199100.0 199352.3 185623.5 324162.7 243142.4 334992.0 298955.69999999995 257228.8 283010.5 396008.0 249636.2 True False 196509.4996452655 185193.70019042367 297511.29411020793 261023.9031952696 315288.42917961243 286170.0616107746 270546.84863381553 296160.2010106253 351405.4088908886 292785.4845506717 0.6711722746325426 0.6325235025726579 1.0161408601481345 0.8915192759499483 1.0768581293006219 0.9774052222908196 0.9240446091411086 1.011526242378896 1.2002145851942727 1.0 18.159484505224547 -5.2623627476287576 24.996578394154024 1.0062314450745327 0.6518478605460293 0.7634978013367387 0.08017108460933113 35.84031754025031 970269.1048793576 0.020999617938590474 0.04821172396875268 5.46559254588344e-06 5.2623627476287576 -0.3543835845285034 YSHSYLS(ph)DSDTEAK ddPTM_PC-9_AZD4547_30min_R2 3 YSHSYLSDSDTEAK 14 0 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614;Q92614-5;Q92614-2 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 YSHSYLS(0.998)DS(0.002)DTEAK;YSHSYLS(0.656)DS(0.327)DT(0.016)EAK;YSHSYLS(0.993)DS(0.007)DTEAK 180.95 3.2191e-05 56241000.0 147719.0 157771.0 200082.0 213419.0 185985.0 192948.0 179477.0 187640.0 175159.0 179837.0 True False 194690.56925392523 208767.39036993834 197428.78194874368 164218.54684068085 160164.1930847842 180882.9310582057 195450.1053069807 158644.54953824627 184417.54714581408 173540.96136812225 1.1218709849194597 1.2029862501861581 1.1376494655342468 0.9462811865628293 0.9229186690111582 1.0423068400232574 1.1262476810439228 0.9141619839348643 1.0626744584791135 1.0 17.404916700859694 -5.662743032247678 6.0407739532221 1.002386933174214 1.1635165190688843 0.5414186304671729 0.06427671117774092 0.15872166652404682 8.153460795122545 0.018012802069959394 0.03144289607003822 2.1739871250793467e-06 5.662743032247678 0.1611295858946704 YSHSYLS(ph)DSDTEAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 YSHSYLSDSDTEAK 14 0 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614;Q92614-5;Q92614-2 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 YSHSYLS(0.993)DS(0.007)DTEAK;YSHSYLS(0.935)DS(0.062)DT(0.002)EAK;YSHSYLS(0.917)DS(0.083)DTEAK 213.52 1.1084e-26 16198300.0 72114.3 84106.3 77303.0 101805.5 105776.0 91723.0 97084.9 87716.0 83651.0 67791.2 True False 84321.82666765078 92455.81762482763 79146.19669326014 96101.66789288424 85049.95211936938 86912.88441088682 87888.31543819247 85413.5479427843 84874.23762285584 80081.20792515589 1.0529539807448731 1.1545257622891638 0.9883242116831003 1.2000526763120396 1.0620463192670282 1.0853093586215112 1.0974898820249206 1.066586658165946 1.0598521153949068 1.0 16.28917611514305 -8.70289752273054 0.8540646119371461 0.999928094754578 1.0939929755990618 0.2074764854799067 0.05388475120221062 1.2742839839847186 1.9261579143592433 0.048506631107259356 0.016859812651248092 1.9819946473079576e-09 8.70289752273054 0.09406488084448383 YSHSYLS(ph)DSDTEAK ddPTM_PC-9_Lapatinib_30min_R1 3 YSHSYLSDSDTEAK 14 0 A0A0D9SFK2;Q92614-3;Q92614-4;Q92614;Q92614-5;Q92614-2 A0A0D9SFK2 MYO18A Unconventional myosin-XVIIIa 1 YSHS(0.001)Y(0.001)LS(0.756)DS(0.24)DT(0.001)EAK;YSHSYLS(0.771)DS(0.228)DT(0.002)EAK;YSHSYLS(0.765)DS(0.118)DT(0.118)EAK 191.19 1.5668e-06 61271100.0 79581.0 89027.0 95062.0 73032.0 87597.0 88869.0 78452.0 94844.0 89053.0 80306.0 True False 78446.16034663178 88820.86345130246 87246.36930993164 78403.01690761019 82444.71668232828 85068.28003375734 82513.86069141579 99250.79848504475 79022.91337033683 94186.78509898136 0.83287862797517 0.943028932965067 0.9263122126765873 0.8324205654245027 0.8753321030724928 0.9031870017047366 0.8760662188936756 1.0537656464305645 0.839002130577992 1.0 16.52323703588891 YSIS(ph)LSPPEQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSISLSPPEQQK 12 0 A0A0U1RQT1;A0A087X1H5;Q15057;H7C3K3 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 YSIS(0.868)LS(0.132)PPEQQK 105.65 0.002686 0.0 16306.0 17902.0 14769.0 16329.0 17831.0 14525.0 14215.0 13169.0 17148.0 13030.0 True False 19066.28374181979 19679.192249803687 15121.148971744411 15414.139069332277 14337.143550904511 13763.283430198875 12868.452292312248 12823.327703708863 17398.75705917124 15392.235854576746 1.2386948798053012 1.2785142090940773 0.9823880763396873 1.0014230041017087 0.9314529537072737 0.894170512993178 0.8360352851847659 0.8331036390594262 1.1303593073515614 1.0 13.909915190294294 -5.32642342597007 3.4804569564571666 0.9351194095499897 1.264318978155948 0.6808423126629157 0.08396493279883538 0.1276882659529301 3.0370220903945326 0.02306937136309826 0.05712003359290585 4.716030162105378e-06 5.32642342597007 0.32919956860595834 YSISLS(ph)PPEQQK ddPTM_PC-9_AZD4547_30min_R2 1 YSISLSPPEQQK 12 0 A0A0U1RQT1;A0A087X1H5;Q15057;H7C3K3 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 Y(0.011)S(0.115)IS(0.121)LS(0.753)PPEQQK 130.61 0.00014082 11966000.0 14301.0 14419.0 17840.0 16761.0 16223.0 19875.0 21720.0 17894.0 18327.0 14972.0 True False 18848.42052072102 19079.659771086866 17603.429943551066 12897.010404868608 13970.716479363704 18632.213108100816 23653.03792278463 15128.893463213457 19295.727804687962 14447.834837122135 1.3045844400360989 1.3205895545029185 1.218413010807749 0.8926604263035419 0.966976480342056 1.2896197470521589 1.6371337428367283 1.0471391480986076 1.3355446004345022 1.0 13.818565685161728 -6.898047551339759 19.66995271453486 1.288461908301523 1.1398710655846245 0.07292217556665437 0.2054766988667261 6.823423141815187 1293.3482053816492 0.07580371738167391 0.06685274619384077 1.2645978777967705e-07 6.898047551339759 -0.14859084271689849 YSISLS(ph)PPEQQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YSISLSPPEQQK 12 0 A0A0U1RQT1;A0A087X1H5;Q15057;H7C3K3 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 YSIS(0.034)LS(0.966)PPEQQK;YSIS(0.002)LS(0.998)PPEQQK 135.58 7.4808e-05 2636000.0 26852.0 41414.0 28607.0 27420.0 36325.0 22018.6 33613.0 21080.0 21901.0 22273.0 True False 31397.513248825282 45525.308224409 29289.099372651643 25883.746296839425 29207.37701119436 20863.905854470006 30428.933302954025 20526.672336106232 22221.260692378673 26310.918587029024 1.1933263806419854 1.7302819768083826 1.113191820945804 0.9837644478744961 1.1100857963048563 0.7929751971774815 1.1565135288721973 0.7801579510882468 0.8445642298225763 1.0 14.683373997411564 -5.466586092242126 5.188907974203513 0.9572567131609074 1.4613772577743487 0.5889633800802061 0.1679255051825629 0.1299640816955649 7.415668251245007 0.042551136867190434 0.08884623425328605 3.4151824320424763e-06 5.466586092242126 0.5041205446134412 YSISLS(ph)PPEQQK ddPTM_PC-9_Lapatinib_30min_R1 2 YSISLSPPEQQK 12 0 A0A0U1RQT1;A0A087X1H5;Q15057;H7C3K3 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 YS(0.001)IS(0.4)LS(0.6)PPEQQK;YSIS(0.23)LS(0.77)PPEQQK 145.52 0.00011111 25251000.0 35999.0 65124.0 54475.0 52186.0 68895.0 62547.0 67598.0 70589.0 57738.0 54534.0 True False 35485.64765859193 64973.20937920667 49996.275779581 56023.93252739267 64842.73155278155 59872.01061417832 71097.89368044582 73868.82263781379 51234.938431905815 63960.12923801265 0.5548088798654612 1.015839244749242 0.7816787798150245 0.8759196267242163 1.0137992578389656 0.9360833276521167 1.1115970922427574 1.1549198464394632 0.8010449485060761 1.0 15.964885233484198 -3.9885017351139482 0.5705976030556206 1.0133544417579596 7.150181127136255e-13 0.435994937195477 0.126766241409259 8.85095117036665 1.1161645552174277 0.06301844246939708 7.24160714750118 0.00010268293292225687 3.9885017351139482 -1.0133544417572447 YSISLS(ph)PPEQQKK ddPTM_PC-9_Lapatinib_30min_R1 1 YSISLSPPEQQKK 13 1 A0A0U1RQT1;A0A087X1H5;Q15057;H7C3K3 A0A0U1RQT1 ACAP2 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 1 YSIS(0.017)LS(0.983)PPEQQKK 88.09200000000001 0.0099515 6319500.0 36886.0 28365.0 37746.0 34635.0 34468.0 42722.0 35654.0 37406.0 43219.0 36752.0 True False 36359.99887593604 28299.322585240392 34642.66958377355 37182.173438973 32440.660006695296 40894.87964984613 37499.98966363819 39144.01931731668 38351.221103753815 43104.53423103827 0.8435307218736703 0.65652774331251 0.8036896860569349 0.8626046911834914 0.752604350920831 0.9487373052368808 0.869977841835386 0.9081183688821826 0.8897259137099842 1.0 15.395552016115918 -6.641498833086342 0.25886722901464726 1.0056874925266648 0.6779391252080657 0.533529572460519 0.06360973291462732 2.6281482440423556 0.35922718986886254 0.10884291919895647 0.2836242461533669 2.2829750588377044e-07 6.641498833086342 -0.32774836731859913 YSLDPENPTK ddPTM_PC-9_Lapatinib_30min_R1 2 YSLDPENPTK 10 0 A0A087WXM6;J3QQT2;J3KRX5;A0A0A6YYL6;P18621;P18621-3;J3KSJ0;A0A087WY81;J3KRB3;A0A087WWH0;J3QS96 A0A087WXM6 RPL17;RPL17-C18orf32 60S ribosomal protein L17 0 ; 137.95 0.00054486 14704900.0 126575.0 131005.0 129889.0 141270.0 137676.0 140431.0 143957.0 116297.0 118967.0 129582.0 False True 124770.01728898796 130701.66597142351 119210.02780603938 151659.467062905 129578.16836143029 134425.0934906499 151410.38907298908 121700.58318307165 105567.68368195176 151980.0760428381 0.8209629876341125 0.8599921080088359 0.784379314117714 0.9978904538786865 0.8525997073781338 0.8844915530425183 0.9962515680694327 0.8007666948973516 0.6946152839941715 1.0 17.213522679169934 YSLEPVAVELK ddPTM_PC-9_Lapatinib_30min_R1 2 YSLEPVAVELK 11 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 ; 129.7 0.0011343 9791200.0 76733.0 70126.0 70649.0 64045.0 69384.0 57898.0 78362.0 70810.0 67141.0 68273.0 False True 75638.77334889125 69963.62755552863 64840.51193302657 68755.08294785708 65302.96953419242 55421.83750683002 82419.20093178927 74100.09110461404 59578.87355392619 80073.89708194583 0.944612115874468 0.8737382605960768 0.8097584143640498 0.8586453944847304 0.8155337995771934 0.6921336356355 1.029289243252933 0.9253963376951876 0.7440486316402773 1.0 16.28904440136158 -7.274630475753832 24.99418280452171 0.9184665624554226 0.8336791168061273 0.1928142645265627 0.09212479334496979 1555.4456986027471 2947210.926651591 0.039018758907830055 0.02648921585295239 5.313363453363489e-08 7.274630475753832 -0.0847874456492953 YSLQSANASSLSSGQLKS(ph)PSLSQSQASR ddPTM_PC-9_AZD4547_30min_R2 2 YSLQSANASSLSSGQLKSPSLSQSQASR 28 1 Q9H2P0;A0A669KBJ7;A0A2R8Y6X0 Q9H2P0 ADNP Activity-dependent neuroprotector homeobox protein 1 YSLQSANAS(0.003)S(0.003)LS(0.018)S(0.164)GQLKS(0.722)PS(0.078)LS(0.011)QS(0.002)QASR;YSLQSANAS(0.004)S(0.004)LS(0.122)S(0.242)GQLKS(0.415)PS(0.172)LS(0.03)QS(0.009)QASR 86.641 1.8219000000000002e-07 33479000.0 5569.0 9655.1 17830.8 27954.0 19833.3 14488.7 9645.2 21140.2 11557.900000000001 20756.3 True False 7339.826157604037 12775.922259228842 17594.351941562254 21509.637184994743 17079.78864267794 13582.719298583163 10503.604114771757 17873.46784346849 12168.826998079496 20029.62825472603 0.36644844648438196 0.6378511920816273 0.8784162999835422 1.0738909834694261 0.852726192691466 0.6781313724770849 0.5244033479399903 0.8923514513681107 0.6075413304392325 1.0 14.28984802486182 -4.884706376404511 2.973429027675985 0.804025071450138 0.34073268170165827 0.420585210034918 0.1616063950171141 0.33258375697944875 4.873477999355668 0.044113126755393056 0.32919487294664956 1.3040481387054547e-05 4.884706376404511 -0.46329238974847975 YSLQSANASSLSSGQLKS(ph)PSLSQSQASR ddPTM_PC-9_Lapatinib_30min_R1 1 YSLQSANASSLSSGQLKSPSLSQSQASR 28 1 Q9H2P0;A0A669KBJ7;A0A2R8Y6X0 Q9H2P0 ADNP Activity-dependent neuroprotector homeobox protein 1 YSLQSANAS(0.006)S(0.006)LS(0.01)S(0.084)GQLKS(0.397)PS(0.156)LS(0.293)QS(0.046)QAS(0.001)R 65.744 0.00013731 9197200.0 3238.4 7583.8 8085.6 4999.1 10454.0 9458.3 9356.8 7894.8 12171.0 10316.0 True False 3192.219822150175 7566.24017704728 7420.833179318596 5366.750490508732 9839.116273354788 9053.790557374177 9841.249320825986 8261.621229384371 10800.17381368814 12099.106854794038 0.26383929495467834 0.6253552652978929 0.6133372709555197 0.44356583960428947 0.8132101312466902 0.7483023884351255 0.8133864291748594 0.6828290161030244 0.8926422374233994 1.0 13.562612932527207 -5.045114834131169 0.2325701467529202 0.9872578408609887 1.862531352774567e-15 0.7179122382975499 0.10928895683977292 5.855035208028454 0.3105585607382453 0.18722376600033605 1.6693602814338546 9.013327798644182e-06 5.045114834131169 -0.9872578408609868 down YSLQSANASSLSSGQLKSPSLS(ph)QSQASR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSLQSANASSLSSGQLKSPSLSQSQASR 28 1 Q9H2P0;A0A669KBJ7;A0A2R8Y6X0 Q9H2P0 ADNP Activity-dependent neuroprotector homeobox protein 1 YSLQSANAS(0.007)S(0.007)LS(0.048)S(0.048)GQLKS(0.207)PS(0.214)LS(0.335)QS(0.129)QAS(0.005)R 54.66 0.0016243 8006700.0 3362.4 2551.5 5271.1 9580.7 9274.4 11100.0 7409.5 10813.0 10044.0 6403.3 True False 3931.5879095728487 2804.7960577239473 5396.78301475807 9043.924440048482 7457.147896837464 10517.896459566775 6707.618519865465 10529.170207320529 10190.874498618841 7564.16760150509 0.5197647800387919 0.37080035841165915 0.7134668742247644 1.1956271881454552 0.9858517539132354 1.3904896101818214 0.8867622814876296 1.3919800250361287 1.3472565701202996 1.0 12.884965614525836 -5.613909431299902 2.8389160108902836 1.1810964085416613 0.4484801337587456 0.7541628445822821 0.17051507814115482 0.11892174141660977 1.920779464107266 0.04731346144142699 0.09455339107544929 2.4327112789914513e-06 5.613909431299902 -0.7326162747829157 YSLS(ph)PSK ddPTM_PC-9_AZD4547_30min_R2 3 YSLSPSK 7 0 P49792;J3KQ37;F8VYC4;A0A286YES2;A0A1W2PNU4;J3KNE0;P0DJD0;P0DJD1;Q7Z3J3;A6NKT7;Q99666;O14715;F8W705;Q99666-2 P49792;Q99666 RANBP2;RGPD8;RGPD1;RGPD3;RGPD2;RGPD4;RGPD5 E3 SUMO-protein ligase RanBP2;RANBP2-like and GRIP domain-containing protein 1;RANBP2-like and GRIP domain-containing protein 2;RanBP2-like and GRIP domain-containing protein 4;RanBP2-like and GRIP domain-containing protein 3;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8 1 Y(0.005)S(0.005)LS(0.937)PS(0.053)K;YSLS(0.977)PS(0.023)K;YSLS(0.957)PS(0.043)K 120.31 0.0061126999999999996 328228000.0 1891710.0 1568810.0 1964800.0 2008540.0 2160110.0 1935190.0 2071090.0 2186180.0 2017780.0 2024450.0 True False 2493234.429987637 2075897.1527483729 1938745.4682224882 1545502.134633662 1860216.0127127124 1814182.2633794022 2255412.9977670317 1848356.1144186838 2124435.731420487 1953574.6216946251 1.2762422291424347 1.0626147215956558 0.9924092208675022 0.7911149732755121 0.9522113934399246 0.9286475383293487 1.1545056803668843 0.9461405230660349 1.0874607541623615 1.0 20.89768493326278 -4.786145098826496 2.3688213535087055 0.9769230433505994 1.3452866950180515 0.48801297732640414 0.09108838845964765 0.5034069396550455 3.4793315656978674 0.024981330156460698 0.38727399752533526 1.6362697484521542e-05 4.786145098826496 0.3683636516674521 YSLS(ph)PSK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YSLSPSK 7 0 P49792;J3KQ37;F8VYC4;A0A286YES2;A0A1W2PNU4;J3KNE0;P0DJD0;P0DJD1;Q7Z3J3;A6NKT7;Q99666;O14715;F8W705;Q99666-2 P49792;Q99666 RANBP2;RGPD8;RGPD1;RGPD3;RGPD2;RGPD4;RGPD5 E3 SUMO-protein ligase RanBP2;RANBP2-like and GRIP domain-containing protein 1;RANBP2-like and GRIP domain-containing protein 2;RanBP2-like and GRIP domain-containing protein 4;RanBP2-like and GRIP domain-containing protein 3;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8 1 Y(0.004)S(0.001)LS(0.94)PS(0.055)K;Y(0.002)S(0.002)LS(0.99)PS(0.006)K;YS(0.007)LS(0.992)PSK;Y(0.001)S(0.008)LS(0.99)PS(0.001)K 114.89 0.0084641 606709000.0 3813700.0 3979250.0 3942260.0 4378930.0 4869330.0 4018510.0 4561490.0 4111680.0 3746260.0 3285290.0 True False 4459284.085991545 4374283.642052919 4036258.429504298 4133592.7487826166 3915219.741277886 3807772.261417452 4129392.6448722742 4003752.756685071 3801041.965272389 3880887.0706586647 1.1490373218292884 1.1271349983679155 1.0400350115880244 1.065115442300428 1.0088466038805386 0.9811602842571753 1.06403318872441 1.031659175799092 0.9794260683362981 1.0 21.887955022295223 -5.122899456485649 0.9846798710887062 1.014491964291114 1.1894574967417917 0.7608887173683073 0.02689254204545954 0.6117478923680638 0.6854499195378421 0.00958621369188728 0.10097608128600524 7.535299932685869e-06 5.122899456485649 0.17496553245067759 YSLS(ph)PSK ddPTM_PC-9_Lapatinib_30min_R1 2 YSLSPSK 7 0 P49792;J3KQ37;F8VYC4;A0A286YES2;A0A1W2PNU4;J3KNE0;P0DJD0;P0DJD1;Q7Z3J3;A6NKT7;Q99666;O14715;F8W705;Q99666-2 P49792;Q99666 RANBP2;RGPD8;RGPD1;RGPD3;RGPD2;RGPD4;RGPD5 E3 SUMO-protein ligase RanBP2;RANBP2-like and GRIP domain-containing protein 1;RANBP2-like and GRIP domain-containing protein 2;RanBP2-like and GRIP domain-containing protein 4;RanBP2-like and GRIP domain-containing protein 3;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8 1 YS(0.002)LS(0.953)PS(0.045)K;Y(0.011)S(0.003)LS(0.985)PS(0.001)K 101.46 0.011192 571720000.0 3009900.0 2771600.0 3028100.0 3014900.0 3278400.0 2685100.0 2681000.0 2881200.0 3146200.0 2405120.0 True False 2966978.2740519363 2765182.530486603 2779141.3068040293 3236625.803411573 3085570.9575823913 2570264.5322738127 2819809.0617662505 3015071.070337716 2791841.8250452396 2820841.78737904 1.0518059847690635 0.9802685648158409 0.9852170083548868 1.14739714148196 1.0938475781902401 0.9111693338398645 0.9996338945284312 1.068855078589552 0.9897193942377231 1.0 21.427694321045408 -6.718600450260779 24.999992795131114 0.9985380551691031 1.0493605819613014 0.19882340819347255 0.05757020717482089 298.2024987985307 174024.48540076273 0.020731847332382522 0.02073171282558632 1.9116111268498147e-07 6.718600450260779 0.05082252679219834 YSLVSEQLEPAAT(ph)STYR ddPTM_PC-9_AZD4547_30min_R2 1 YSLVSEQLEPAATSTYR 17 0 Q9Y446;Q9Y446-2;E9PKC4;E9PK71;E9PQ15;E9PJR7;E9PRW6 Q9Y446 PKP3 Plakophilin-3 1 YSLVSEQLEPAAT(0.266)S(0.266)T(0.266)Y(0.202)R 80.69 0.027433999999999997 0.0 6515.2 9025.6 7968.8 14226.0 10418.0 12653.0 9920.7 12022.0 10357.0 10268.0 True False 8586.898075421414 11942.948694772289 7863.128505278578 10946.415489509027 8971.640527769898 11861.805909776085 10803.623081057534 10164.276138077124 10904.449875765436 9908.520445335957 0.8666175866310449 1.2053210931601759 0.7935724156455503 1.1047477320048946 0.9054470419943416 1.197131900288863 1.0903366593084955 1.0258116934967374 1.1005124262420303 1.0 13.274453932837183 -6.749622665924482 24.99742618570815 1.0848454179753473 0.9850421799577114 0.16547258755321415 0.11976656243357503 431.4071393229097 912610.3779939603 0.03706970317639717 0.036785940411910516 1.779825128506614e-07 6.749622665924482 -0.09980323801763591 YSPPAIS(ph)PLVSEK ddPTM_PC-9_AZD4547_30min_R2 4 YSPPAISPLVSEK 13 0 Q14694;Q14694-3;Q14694-2 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 YSPPAIS(0.998)PLVS(0.002)EK;Y(0.003)SPPAIS(0.937)PLVS(0.06)EK;Y(0.001)S(0.042)PPAIS(0.957)PLVSEK;YSPPAIS(1)PLVSEK 127.07 0.0001216 50739000.0 204159.0 174713.0 260716.0 331220.0 283923.0 261241.0 225120.0 280770.0 233476.0 264861.0 True False 269077.3152289966 231185.5605510716 257258.73549119197 254862.34629798788 244505.1923177201 244905.5589722453 245155.24388477372 237383.44795274676 245817.06470929892 255588.29700741384 1.0527763531410497 0.9045232636154917 1.0065356610742222 0.9971596872081944 0.9566368851020896 0.9582033365367324 0.9591802392957863 0.9287727596771028 0.9617696412061015 1.0 17.963462253460747 -6.277875773690454 22.82575144538329 0.9569922388587152 0.9852888426563219 0.11713905157378623 0.0378750549909874 578.2549798855242 803039.4782662513 0.011202813713566176 0.01275151902648696 5.273806926925165e-07 6.277875773690454 0.02829660379760668 YSPPAIS(ph)PLVSEK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YSPPAISPLVSEK 13 0 Q14694;Q14694-3;Q14694-2 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 Y(0.002)S(0.012)PPAIS(0.974)PLVS(0.011)EK;YS(0.001)PPAIS(0.999)PLVSEK;Y(0.349)S(0.028)PPAIS(0.62)PLVS(0.004)EK;Y(0.001)SPPAIS(0.985)PLVS(0.014)EK 105.58 0.001213 36399000.0 137674.0 136012.0 162104.0 166547.0 206335.0 185405.0 183978.0 180680.0 176454.0 133940.0 True False 160979.48901455267 149514.37248800645 165969.17414284326 157215.91154265899 165905.1379381905 175682.0354131512 166550.27195462707 175937.34144628418 179034.30593182912 158222.2617315433 1.0174262916787753 0.9449641968946724 1.048962215092363 0.9936396422483722 1.0485574919898617 1.1103496656572387 1.052634882929521 1.111963256755855 1.1315367633639175 1.0 17.271593074438314 -6.464337432189127 3.3742713802809066 1.086479805885021 1.0007455692756664 0.4407878043851233 0.04213680184297995 0.21521316942703833 4.856533848805197 0.013497391561870254 0.014905014796958552 3.4329111861454885e-07 6.464337432189127 -0.08573423660935453 YSPPAIS(ph)PLVSEK ddPTM_PC-9_Lapatinib_30min_R1 3 YSPPAISPLVSEK 13 0 Q14694;Q14694-3;Q14694-2 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 YSPPAIS(0.998)PLVS(0.001)EK;YSPPAIS(0.957)PLVS(0.043)EK;YSPPAIS(0.997)PLVS(0.003)EK 130.95 7.4226e-05 29076300.0 124435.0 93144.0 113458.0 102126.0 105091.0 111897.0 98997.0 89308.0 112902.0 83848.0 True False 122660.53408141552 92928.33079075011 104129.92120054548 109636.68672234911 98909.75399685555 107111.42615464705 104122.5802639587 93457.57571488335 100185.78784923328 98341.015079563 1.247297823620966 0.9449600526857106 1.0588656331877289 1.1148622640680221 1.0057833338087105 1.0891836541242566 1.0587909854267634 0.9503417840386466 1.0187589356097022 1.0 16.585505626335937 -4.746693610979621 24.9480923431638 1.0313271168053486 1.247298405280298 0.6117340490766459 0.052581249264626935 555.5706768826526 939905.8576539615 0.013349387338349093 0.29537091199499477 1.7918695485206406e-05 4.746693610979621 0.2159712884749494 YSPS(ph)QNS(ph)PIHHIPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSPSQNSPIHHIPSR 15 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 Y(0.439)S(0.398)PS(0.686)QNS(0.477)PIHHIPSR 60.55 0.022886 1237000.0 6702.7 7893.0 9300.7 7509.1 8889.9 7648.9 8847.7 6133.8 7568.6 7001.4 True False 7837.334725640595 8676.564876980254 9522.463961101173 7088.3894718306665 7147.987911681122 7247.778218881107 8009.581804199157 5972.794249298309 7679.276456615554 8270.69839694809 0.9476025299789185 1.049072818346505 1.1513494391979024 0.8570484778463572 0.8642544521172176 0.87631997577805 0.9684287130038153 0.7221632276546666 0.9284918985135799 1.0 13.013793443716612 -5.7792558362374375 24.998890702875396 0.8783869102344216 1.0493147293091936 0.4309191207901505 0.08439756734091482 199.64330836541 280125.8387976976 0.02315192569556813 0.03442144314106868 1.6624330479798408e-06 5.7792558362374375 0.17092781907477195 YSPS(ph)QNSPIHHIPSR ddPTM_PC-9_AZD4547_30min_R2 1 YSPSQNSPIHHIPSR 15 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 Y(0.099)S(0.122)PS(0.514)QNS(0.266)PIHHIPSR 60.657 0.043185 25920000.0 41343.0 35978.0 71086.0 63433.0 56926.0 59893.0 50999.0 54886.0 51983.0 48141.0 True False 54489.214012178774 47607.18491186371 70143.35319323269 48809.50188008055 49022.80751428579 56147.88124193626 55537.81220184592 46404.629854807994 54730.71525460219 46455.598242980006 1.1729310583232613 1.024788975116852 1.509900977409804 1.0506699671542008 1.05526156950726 1.2086354145793585 1.1955031105478948 0.9989028579955976 1.1781295973919064 1.0 15.50356484205023 -8.730958614204148 0.3240325562929571 0.9798380857176655 1.1957619235843782 0.12036607080600448 0.13755211733568515 5.073646833756929 1.3476623779619603 0.364885872088703 0.1682780700027339 1.8579815017332396e-09 8.730958614204148 0.21592383786671265 YSPS(ph)QNSPIHHIPSR ddPTM_PC-9_Lapatinib_30min_R1 4 YSPSQNSPIHHIPSR 15 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 Y(0.034)S(0.325)PS(0.398)QNS(0.243)PIHHIPSR;Y(0.046)S(0.416)PS(0.539)QNSPIHHIPSR;Y(0.088)S(0.107)PS(0.481)QNS(0.323)PIHHIPSR;Y(0.281)S(0.328)PS(0.385)QNS(0.006)PIHHIPSR 80.459 0.008478 24654600.0 22552.5 26148.5 60051.8 29323.8 55288.100000000006 56316.5 49429.3 51539.6 59412.3 37094.1 True False 22230.89721437802 26087.95475480906 55114.57281065155 31480.37007332917 52036.16265858679 53907.97457517345 51988.50729457764 53934.31797056017 52720.66113474516 43505.76576021865 0.5109873789350878 0.5996436173217227 1.2668337597920851 0.7235907591382884 1.1960750891130911 1.2390995453863842 1.1949797086922107 1.2397050604239062 1.2118086008487763 1.0 15.408918991601572 -4.741504357022255 0.7580598694753846 1.1862504951771586 1.0107604454916163e-15 0.631880648191834 0.1694103288169335 1.7849129956327248 0.7490702862659029 0.06599215999253541 1.833759052421861 1.8134084829139945e-05 4.741504357022255 -1.1862504951771575 YSPSQNS(ph)PIHHIPSR ddPTM_PC-9_AZD4547_30min_R2 1 YSPSQNSPIHHIPSR 15 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 Y(0.005)S(0.006)PS(0.032)QNS(0.956)PIHHIPSR 61.641000000000005 0.039873 22851000.0 34469.0 25878.0 52159.0 71369.0 47619.0 53693.0 53833.0 71982.0 56578.0 51267.0 True False 45429.42500026099 34242.55742812857 51467.3375799148 54915.97969005828 41007.923813771835 50335.56822205067 58624.03271166045 60858.83588180573 59568.59757372372 49472.15793446034 0.9182826643714416 0.6921581523387839 1.0403293433873984 1.1100380897637374 0.8289091385117718 1.0174524484809044 1.1849904099458188 1.2301633569821278 1.2040832674539672 1.0 15.59432920957853 -7.0997676454688765 3.6378279261324318 1.1732417023074249 0.9224140519555403 0.45548202943224725 0.12090915622512023 0.22528165928455884 5.4730965233279925 0.050492311521671406 0.03883235810903607 7.947533268077927e-08 7.0997676454688765 -0.2508276503518846 YSPSQNS(ph)PIHHIPSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YSPSQNSPIHHIPSR 15 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 YSPS(0.001)QNS(0.998)PIHHIPSR;YS(0.001)PS(0.004)QNS(0.995)PIHHIPSR 76.52600000000001 0.011956 20348700.0 68075.0 72547.0 66700.0 90336.0 102406.0 74779.0 76457.0 64140.0 57664.0 53408.0 True False 79598.75295746239 79748.98671357991 68290.38096115849 85274.76679326352 82340.27942762217 70857.45759909404 69214.43945925558 62456.39296194751 58507.22691042979 63090.447622504624 1.2616609321546355 1.264042176253844 1.0824202955377198 1.3516272273656473 1.3051148395759844 1.123109127756749 1.097066863012183 0.9899500687592055 0.9273547599551349 1.0 15.945133966201396 -7.358293556733961 1.5165787965598765 0.9643657892682718 1.2466394691630658 0.7339768539486242 0.0720264096895445 0.219154637971983 0.9767027161197955 0.04604910941335933 0.025292573073698255 4.382343777744394e-08 7.358293556733961 0.282273679894794 YSPSQNS(ph)PIHHIPSR ddPTM_PC-9_Lapatinib_30min_R1 1 YSPSQNSPIHHIPSR 15 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 YSPS(0.002)QNS(0.998)PIHHIPSR 98.165 0.0019925999999999998 20273000.0 53531.0 49426.0 67007.0 46728.0 67969.0 57955.0 51939.0 54710.0 63457.0 50621.0 True False 52767.63812361688 49311.557133724404 61497.94311450003 50164.53300003842 63971.19705219545 55476.39974970351 54628.14728052118 57252.02632867441 56309.80442816595 59370.772401757335 0.8887813984723398 0.8305695738643416 1.0358285841111903 0.8449365061410854 1.0774863533744754 0.9344058954513693 0.9201185207909511 0.9643133146601911 0.9484431842510309 1.0 15.857465261949212 -5.24475255501213 24.983729017086805 0.9613520618125512 0.8596754774357497 0.31725388268975985 0.06194852235055575 947.1996893805252 1418154.7169873428 0.014716427999041078 0.0387134218639503 5.691771346270607e-06 5.24475255501213 -0.1016765843768015 YSPT(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 1 YSPTSPK 7 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YSPT(0.726)S(0.274)PK 88.177 0.042656 198480000.0 243200.0 215110.0 232280.0 314050.0 268900.0 254210.0 256140.0 248690.0 213700.0 242220.0 True False 320532.54112574935 284640.10079467995 229199.815430944 241650.62452413255 231567.87655186467 238314.20851372648 278935.9637910706 210260.67482768235 224995.74572280337 233739.95152603043 1.3713211585485132 1.2177640105439187 0.9805761228859465 1.033843906214814 0.9907073011695912 1.0195698551224635 1.193360236322317 0.8995495783024781 0.9625900247427182 1.0 17.834544819350796 -5.032158034700839 2.714422380478944 1.0131719943720914 1.3718857433765874 0.7301218053708544 0.07186682125434463 0.15879772198196318 2.1250290730587356 0.019598140501840333 0.0989171638175204 9.286284082346125e-06 5.032158034700839 0.35871374900449604 YSPT(ph)SPT(ph)YSPTTPK ddPTM_PC-9_Lapatinib_30min_R1 1 YSPTSPTYSPTTPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 2 Y(0.006)S(0.021)PT(0.792)S(0.181)PT(0.395)Y(0.02)S(0.28)PT(0.272)T(0.032)PK 101.45 0.008698000000000001 10869000.0 38383.0 30977.0 31030.0 26522.0 33228.0 36840.0 30555.0 30178.0 29993.0 33372.0 True False 37835.65138141988 30905.274659721224 28478.83317926386 28472.516354798372 31273.59436876149 35264.439078234456 32136.988393236777 31580.180050205396 26614.872499708163 39140.305734605136 0.966667241640073 0.7896022803009668 0.72760885856047 0.7274474693135816 0.7990125212821614 0.9009750541385294 0.8210714707019646 0.8068455127647202 0.6799863210107003 1.0 15.256367404805836 -6.550058881506347 24.97562941881824 0.8308077533527679 0.7923529791986552 0.029518949673734918 0.09785862754975448 955.9131199963236 878374.4404641571 0.03252901752397943 0.032529614618279176 2.818000841714364e-07 6.550058881506347 -0.03845477415411269 YSPT(ph)SPTYSPT(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 2 YSPTSPTYSPTSPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 2 Y(0.001)S(0.006)PT(0.574)S(0.42)PT(0.001)YS(0.365)PT(0.624)S(0.009)PK;YS(0.003)PT(0.519)S(0.479)PTYS(0.454)PT(0.516)S(0.03)PK 193.45 9.3015e-37 7168500.0 62621.0 59856.0 64318.0 72294.0 62053.0 70691.0 68126.0 70858.0 57157.0 53940.0 True False 82533.17540228464 79203.28145212395 63465.10129536532 55627.73523116584 53438.012062747686 66270.68059495625 74189.08202245041 59908.52425485516 60178.20233167182 52051.5770180582 1.5856037440258823 1.5216307745036435 1.2192733617532365 1.0687041280587324 1.0266357932672914 1.273173348272715 1.425299410173722 1.1509454215781236 1.1561263996054194 1.0 15.66765425338473 -5.256384005845198 3.623355868460273 1.171971681309564 1.5708786124432834 0.641328326427695 0.11704943120768412 0.15251080208588877 4.408928179157559 0.03355775579963548 0.0918002748645531 5.541355262449952e-06 5.256384005845198 0.39890693113371944 YSPT(ph)SPTYSPT(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSPTSPTYSPTSPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 2 Y(0.005)S(0.006)PT(0.936)S(0.055)PT(0.004)YS(0.001)PT(0.988)S(0.003)PK 150.12 4.7747000000000004e-08 0.0 29364.0 34007.0 25253.0 34345.0 33222.0 27502.0 33464.0 31985.0 24401.0 25852.0 True False 34334.745234563765 37382.99021556662 25855.12729253582 32420.76099799235 26712.38758612245 26059.74670549599 30294.04766162058 31145.4276409088 24757.818462843337 30538.762955680595 1.124300459857922 1.2241160609491195 0.846633091525616 1.0616265316654445 0.8747043102200579 0.8533334091926126 0.9919867319309836 1.019865398153443 0.8107014190055157 1.0 14.898354003116737 -5.255816360805875 24.999556687136298 0.9349310366700765 1.174208278532055 0.5745862737308852 0.08321746727540373 308.5207205074366 1371651.7022033124 0.020586082529666882 0.051347527588305554 5.548602831858076e-06 5.255816360805875 0.2392772418619784 YSPT(ph)SPTYSPT(ph)SPK ddPTM_PC-9_Lapatinib_30min_R1 3 YSPTSPTYSPTSPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 2 YS(0.003)PT(0.969)S(0.028)PTYS(0.017)PT(0.981)S(0.001)PK;YS(0.001)PT(0.936)S(0.063)PTYSPT(0.999)S(0.001)PK;YS(0.005)PT(0.916)S(0.081)PT(0.001)YS(0.025)PT(0.956)S(0.016)PK 230.23 3.5776e-20 68050000.0 215952.0 197702.0 178583.0 171322.0 190762.0 182031.0 179350.0 178489.0 175792.0 170088.0 True False 212872.48487925332 197244.23316577452 163900.5950903151 183921.59139343866 179541.75421252218 174245.95846498632 188635.86543371013 186782.2505461302 155992.453788174 199487.48417198643 1.0670969447673575 0.9887549285835 0.8216084120295466 0.9219705795420841 0.900015131063219 0.8734681235177725 0.9456025084314529 0.9363106228012654 0.7819661190056737 1.0 17.605938709157975 -5.0193089100807 4.809866129406183 0.8970922517805185 1.0537077177677618 0.4614030399946386 0.05910159012210718 0.13907608573891778 8.839923133416706 0.01427472491402097 0.04891524521753763 9.565134691337997e-06 5.0193089100807 0.1566154659872433 YSPT(ph)SPTYSPTTPK ddPTM_PC-9_Lapatinib_30min_R1 3 YSPTSPTYSPTTPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YS(0.019)PT(0.895)S(0.083)PT(0.002)YSPTTPK;YSPT(0.959)S(0.041)PTYSPTTPK;YS(0.139)PT(0.477)S(0.376)PT(0.007)YSPTTPK 241.76 2.3386e-27 366296000.0 610500.0 526650.0 546210.0 491980.0 629800.0 648410.0 563680.0 546030.0 615400.0 472930.0 True False 601794.1580480102 525430.5742822791 501302.7222315744 528161.8503971697 592756.4022344401 620679.015817535 592864.5922925773 571400.5471805168 546087.171550709 554675.3203603865 1.0849485022283114 0.9472759197955547 0.9037768651864039 0.952200018659582 1.0686547255235934 1.1189951905815174 1.0688497766718343 1.0301531836845805 0.9845168001992634 1.0 19.081284010273656 -6.259872789611232 24.94824982309866 1.0515753602048383 0.9654040476275018 0.2837905756534175 0.055984895110900976 165.94482025510638 2642706.658703388 0.017814452389372574 0.02179227705755221 5.497018649604159e-07 6.259872789611232 -0.08617131257733657 YSPTS(ph)PK ddPTM_PC-9_AZD4547_30min_R2 2 YSPTSPK 7 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YSPT(0.308)S(0.691)PK;YSPT(0.141)S(0.859)PK 96.66799999999999 0.012731000000000001 209247000.0 368806.0 376908.0 375878.0 464363.0 451797.0 400579.0 432240.0 428631.0 405897.0 402843.0 True False 486078.63635864836 498736.1401623422 370893.61212567793 357311.2846868326 389072.78513389005 375530.7318052798 470708.52264016727 362395.9279105087 427351.8867648509 388739.58918586525 1.2503965376324022 1.282956904921472 0.9540927202769287 0.9191533217266274 1.0008571186400712 0.9660213218616384 1.2108582087715043 0.932233140106651 1.0993268981424071 1.0 18.568444513458722 -5.256046833427125 24.981616878652716 1.0098839733151956 1.2666767524544278 0.6058840094563359 0.08270323729796714 283.89409575979545 1315162.5564119865 0.021303119798783486 0.052895745200579436 5.54565906482131e-06 5.256046833427125 0.25679277913923215 YSPTS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YSPTSPK 7 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YS(0.001)PT(0.321)S(0.678)PK;YSPT(0.077)S(0.923)PK;YSPT(0.18)S(0.82)PK;YS(0.008)PT(0.223)S(0.77)PK 106.6 0.010031 222816000.0 855651.0 841256.0 817740.0 969215.0 931580.0 881115.0 1102929.0 1029626.0 824632.0 804596.0 True False 1000495.8144224096 924770.3360127811 837238.0228962193 914913.0257874259 749043.5864029856 834907.7782856921 998451.5806055336 1002599.4084789226 836690.682949527 950462.8856215694 1.052640591818712 0.9729683820405189 0.8808739778920405 0.962597319293646 0.7880829412009469 0.8784222834116155 1.0504898147102095 1.0548538229593865 0.8802981111696547 1.0 19.85827076698647 -7.25748361487174 24.748972848355745 1.0009815886154498 0.9186945054454296 0.17031934066678844 0.079274864886387 525.7254852308448 3289179.9881363893 0.03263194238689869 0.024291360840165966 5.527342611933205e-08 7.25748361487174 -0.0822870831700202 YSPTS(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 2 YSPTSPK 7 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YSPT(0.163)S(0.837)PK;YSPT(0.119)S(0.881)PK 95.35799999999999 0.013152 236750000.0 534590.0 448230.0 425120.0 433530.0 437300.0 419520.0 445470.0 408350.0 427650.0 362333.0 True False 526966.6485682019 447192.1509741699 390168.2746106553 465413.2424136854 411578.8737648787 401578.1075488848 468534.2568985494 427323.43175496615 379483.55364585784 424961.77627162467 1.2400330523641692 1.052311468804517 0.91812557363105 1.0951884814134558 0.9685079852965601 0.9449746541256134 1.1025327054334277 1.005557336248124 0.892982792417786 1.0 18.69697355647927 -4.800276995819818 3.502076586633981 0.995780662134231 1.2643875937879967 0.5726325630840567 0.06447921945489297 0.19624259929169732 4.008506015047336 0.016008911320580382 0.1365048666696756 1.5838826596639006e-05 4.800276995819818 0.2686069316537657 YSPTS(ph)PT(ph)YSPTSPK ddPTM_PC-9_AZD4547_30min_R2 1 YSPTSPTYSPTSPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 2 YSPT(0.068)S(0.924)PT(0.55)Y(0.444)S(0.012)PT(0.001)SPK 122.78 0.0014065999999999998 14408000.0 45908.0 38784.0 47053.0 58530.0 48858.0 53773.0 48815.0 56987.0 52042.0 44866.0 True False 60505.78905428018 51320.169537543035 46429.046476115975 45036.812779485655 42074.91005046856 50410.56580940405 53159.44043281456 48180.968580985005 54792.83387415129 43295.25499614758 1.3975154796908806 1.185353211156962 1.0723818691042988 1.0402251420737223 0.9718134251481461 1.164343894357236 1.2278352544070867 1.1128463981854861 1.2655621009514038 1.0 15.401921298990148 -4.799961960274154 2.9476064850280213 1.1104977365541366 1.439391742154425 0.49298916017742067 0.0887784178670359 0.33791474494270957 4.3259380802143 0.0240085613707494 0.2622129521399427 1.5850320188691596e-05 4.799961960274154 0.32889400560028825 YSPTS(ph)PTYSPT(ph)TPK ddPTM_PC-9_AZD4547_30min_R2 1 YSPTSPTYSPTTPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 2 YSPT(0.034)S(0.965)PT(0.002)YS(0.032)PT(0.898)T(0.068)PK 145.61 0.0049847 8631600.0 26716.0 24583.0 37358.0 37765.0 36821.0 42461.0 31206.0 36749.0 33926.0 38379.0 True False 35211.13227267903 32528.974003233816 36862.60851071645 29058.86271343373 31709.039726724466 39805.90695763871 33983.27354596766 31070.286458010018 35719.25909869829 37035.36289165845 0.9507435468010416 0.8783219999326747 0.9953354208666088 0.784624759812431 0.856182773731275 1.0748080712503096 0.917589862569479 0.8389356558730532 0.9644635912759859 1.0 15.176615853093438 YSPTS(ph)PTYSPTT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 YSPTSPTYSPTTPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 2 YSPT(0.114)S(0.885)PTYS(0.013)PT(0.313)T(0.674)PK 137.73 0.00043803 0.0 26260.0 19876.0 19696.0 20263.0 21691.0 24082.0 23172.0 20216.0 23393.0 21195.0 True False 25885.527584505802 19829.9783431778 18076.67090875866 21753.20861538646 20415.17802614679 23052.068997883867 24371.73277853323 21155.30916213641 20758.23400078929 24858.527509437732 1.0413137936138077 0.7977133132945705 0.7271818856485249 0.8750803364007657 0.8212545179273394 0.9273304297341012 0.9804173947664565 0.8510282499277012 0.8350548516161412 1.0 14.601453220680451 -6.765699456953319 24.98170122659631 0.9133086584314055 0.8437559464687884 0.11748726912069629 0.08856871041107375 243.1896867036406 1426089.0682504363 0.03126786860661101 0.02853940312583615 1.715143820925393e-07 6.765699456953319 -0.06955271196261714 YSPTS(ph)PTYSPTTPK ddPTM_PC-9_AZD4547_30min_R2 3 YSPTSPTYSPTTPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YSPT(0.042)S(0.862)PT(0.048)Y(0.034)S(0.012)PT(0.003)TPK;YS(0.042)PT(0.188)S(0.63)PT(0.139)YS(0.001)PTTPK;YS(0.001)PT(0.268)S(0.654)PT(0.032)Y(0.033)S(0.011)PT(0.001)TPK 103.83 0.001124 180843000.0 354810.0 351183.0 429740.0 603040.0 526400.0 502130.0 391470.0 528790.0 456630.0 521850.0 True False 467632.19949353463 464696.0369921351 424041.3668128718 464018.4448751242 453318.4463254056 470731.7317217946 426310.0716221222 447077.65588536 480766.5295713789 503580.19033877685 0.9286151609318494 0.9227845850717779 0.8420533113655715 0.9214390354850177 0.9001911811114763 0.9347701532999463 0.8465584623877436 0.8877983377078326 0.9546970647275653 1.0 18.941862006377534 -8.478435744429854 3.3701762099283457 0.9993457770111525 0.897553075720428 0.5396482228841375 0.030668706413065308 0.1620739740744074 4.069976498624251 0.029637175302289202 0.007853933102655378 3.3232595050030375e-09 8.478435744429854 -0.10179270129072449 YSPTS(ph)PTYSPTTPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YSPTSPTYSPTTPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YS(0.062)PT(0.041)S(0.87)PT(0.027)YSPTTPK;YSPT(0.05)S(0.928)PT(0.018)Y(0.001)S(0.002)PT(0.001)TPK;YS(0.001)PT(0.04)S(0.954)PT(0.004)YSPTTPK;YS(0.014)PT(0.083)S(0.719)PT(0.181)Y(0.001)S(0.002)PTTPK 155.06 0.00031465 272833000.0 389123.0 375775.0 442430.0 532153.0 537232.0 472713.0 541582.0 511930.0 489248.0 400978.0 True False 454993.8383704255 413079.4585895416 452979.2091251185 502338.19267330406 431965.2461521801 447923.09811632324 490279.4322458699 498492.3799346703 496402.32643371855 473672.13725989807 0.9605670306099849 0.8720788623521886 0.9563138160194852 1.0605187705978096 0.9119498745503919 0.9456395318235773 1.0350607385987316 1.052399625653205 1.0479871780200336 1.0 18.853529285433147 -7.2656232641004115 20.35662019657734 1.0382286158614256 0.9510029358892024 0.4298284687684535 0.04654441161524942 27.714059986938167 134833.55330104043 0.019926218222648936 0.014051042320508243 5.4247126198509136e-08 7.2656232641004115 -0.08722567997222319 YSPTS(ph)PTYSPTTPK ddPTM_PC-9_Lapatinib_30min_R1 1 YSPTSPTYSPTTPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YS(0.007)PT(0.054)S(0.902)PT(0.036)YSPTTPK 132.51 1.3035e-05 25995000.0 149440.0 113850.0 148770.0 130040.0 128100.0 144040.0 133100.0 129530.0 153120.0 127890.0 True False 147308.95819606006 113586.38731992333 136538.70486880708 139603.5754007229 120565.40985429005 137879.74497363967 139991.26673669825 135548.43667251343 135874.0131749181 149995.61609728678 0.9820884238411064 0.7572647139650501 0.9102846364539642 0.9307177038439336 0.8037928906941628 0.9192251651155672 0.9333023882904702 0.9036826555290594 0.9058532289823095 1.0 17.19456081031045 -9.725119989459023 0.3021845839519259 1.0356805127508877 0.8710857938979797 0.22045915858475362 0.0616335869186786 9.931022172525278 1.1891933674245776 0.46242929285798023 0.07139271947485329 1.8831287356176572e-10 9.725119989459023 -0.164594718852908 YSPTSPT(ph)YSPTSPK ddPTM_PC-9_AZD4547_30min_R2 2 YSPTSPTYSPTSPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YSPT(0.002)S(0.018)PT(0.857)YS(0.122)PT(0.001)SPK;YS(0.011)PT(0.02)S(0.228)PT(0.341)Y(0.218)S(0.067)PT(0.105)S(0.011)PK 181.71 6.8093e-05 25315000.0 20735.1 21688.2 28188.1 31268.0 28150.8 27195.0 25426.9 24595.5 21502.9 23752.3 True False 27328.43048312723 28698.486514133165 27814.30737622264 24059.645685784333 24242.547338178618 25494.492350933422 27689.844841567818 20794.830623363505 22639.499394959606 22920.739206637434 1.192301445287306 1.2520750860348604 1.2134995789388903 1.0496889070147044 1.0576686519411387 1.112289273094241 1.208069451510069 0.9072495627602488 0.9877298978387056 1.0 14.484365952115168 -5.765222948012539 0.32387866670028065 0.9699629947217105 1.3370174865482753 0.5142247648410023 0.07647742354526495 3.3033804760307324 0.4541634783163471 0.09392002849562653 0.45466969839423443 1.7170267135823945e-06 5.765222948012539 0.3670544918265648 YSPTSPT(ph)YSPTSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YSPTSPTYSPTSPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YSPT(0.038)S(0.346)PT(0.614)YS(0.001)PTSPK;YSPT(0.015)S(0.139)PT(0.761)Y(0.074)S(0.011)PTSPK 123.02 0.00032638 9886100.0 39110.0 39829.0 43055.0 50099.0 49029.0 50215.0 52922.0 52648.0 40956.0 40829.0 True False 45730.55054228948 43782.95989930906 44081.59448699675 47292.11545314948 39422.1194076214 47581.63700154466 47908.8450379 51266.04578516702 41554.90401886038 48230.97449781383 0.9481572997112532 0.9077768043292099 0.9139685636871143 0.9805341058429805 0.817361038587522 0.986536919416824 0.993321108203434 1.0629278449990838 0.8615812649761813 1.0 15.557672339327057 YSPTSPT(ph)YSPTSPK ddPTM_PC-9_Lapatinib_30min_R1 2 YSPTSPTYSPTSPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YSPT(0.021)S(0.021)PT(0.61)Y(0.013)S(0.326)PT(0.009)SPK;YSPT(0.011)S(0.011)PT(0.916)YS(0.062)PT(0.001)SPK 168.67 0.00083603 146605000.0 84903.0 70878.0 84273.0 78058.0 77462.0 76528.0 64843.0 72486.0 81751.0 68910.0 True False 83692.26765069683 70713.88634573117 77344.3992431875 83798.6457138547 72905.83745615154 73255.0758354811 68200.25326076434 75853.96418315287 72543.34150380574 80821.00168319681 1.0355262358508601 0.8749444435608007 0.9569839228962177 1.0368424539246581 0.9020655020081138 0.9063866360210094 0.8438432070923416 0.9385427376968948 0.8975803317578525 1.0 16.302442611724437 YSPTSPTYS(ph)PTSPK ddPTM_PC-9_AZD4547_30min_R2 3 YSPTSPTYSPTSPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YSPTSPT(0.01)YS(0.47)PT(0.47)S(0.05)PK;YSPTSPTYS(0.994)PT(0.006)SPK;YSPTSPT(0.226)YS(0.773)PTSPK 272.09 1.186e-57 299275200.0 110060.0 110127.0 124035.0 173002.0 142851.0 144555.0 119064.0 136298.0 127144.0 140874.0 True False 145056.7906097867 145723.39909913865 122390.21485697059 133119.06175425558 123018.60443774781 135515.9529983149 129660.46534246916 115236.27591645627 133864.57227037946 135942.04413870818 1.0670487672068423 1.0719523898761598 0.9003117146899011 0.9792339272052422 0.9049341961654338 0.9968656412142919 0.9537922293574633 0.8476867965798365 0.9847179591752425 1.0 17.052632196101136 -5.250100149889981 24.646307579060018 0.9423264355114199 1.0695006074939974 0.5282142748184583 0.04660851471910083 434.1956480234992 943737.7325138882 0.01140435607116172 0.029577269614142625 5.622116621826928e-06 5.250100149889981 0.12717417198257752 YSPTSPTYS(ph)PTSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YSPTSPTYSPTSPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YSPT(0.002)S(0.002)PT(0.017)YS(0.956)PT(0.02)S(0.003)PK;YSPTS(0.001)PT(0.011)Y(0.001)S(0.957)PT(0.029)S(0.001)PK 132.65 1.2605e-05 119018000.0 83610.0 73567.0 80206.0 92601.0 105199.0 83854.0 92429.0 86186.0 74457.0 75350.0 True False 97763.52162722622 80870.24557263455 82118.41522294894 87412.86618649247 84586.01112734037 79456.54862346964 83673.45599198929 83923.70882161525 75545.79276619498 89010.3585297281 1.0983387017205948 0.9085487004933828 0.9225714465077978 0.9820527366744389 0.9502940166125715 0.8926663136283445 0.9400417813623753 0.9428532836836739 0.8487303501981047 1.0 16.441685618211345 -4.7567356317806455 24.995721076728262 0.9310548535787226 1.0983389551962066 0.5975178782828319 0.0409558735066933 97.15651040847031 516227.6930063229 0.009846048915564013 0.0777961416883442 1.750912197631949e-05 4.7567356317806455 0.16728410161748397 YSPTSPTYS(ph)PTSPK ddPTM_PC-9_Lapatinib_30min_R1 2 YSPTSPTYSPTSPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YSPTSPT(0.002)Y(0.006)S(0.972)PT(0.018)S(0.002)PK;YSPT(0.005)S(0.005)PT(0.042)Y(0.006)S(0.781)PT(0.157)S(0.005)PK 137.73 7.5743e-05 20105000.0 79673.0 68418.0 76103.0 78066.0 78099.0 85337.0 62795.0 68043.0 84143.0 62895.0 True False 78536.84840976127 68259.58232458937 69846.10510607528 83807.2340605418 73505.37036854181 81687.3354402632 66046.21784170525 71204.52618318402 74665.92927492895 73766.31694768045 1.0646708641488007 0.9253489281971772 0.94685634305986 1.1361179130033425 0.996462523954887 1.1073798831274282 0.8953438449224629 0.9652715376001026 1.0121954350504792 1.0 16.170674585192902 -10.638521147402077 8.343714784138712 0.9999999998501206 1.0035800821487906 0.0 0.0739715935583751 2.0179400189782903e-10 6.133162767878686e-19 0.07203430800486649 0.017470885135010553 2.2986817752346372e-11 10.638521147402077 0.0035800822986700176 YSPTSPTYSPT(ph)SPK ddPTM_PC-9_AZD4547_30min_R2 1 YSPTSPTYSPTSPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YSPTSPT(0.001)Y(0.003)S(0.014)PT(0.966)S(0.016)PK 103.11 0.0031664 21388000.0 22562.0 23144.0 24793.0 29332.0 28617.0 28905.0 25466.0 28199.0 24508.0 28300.0 True False 29736.24668124659 30624.84539441254 24464.22862054157 22569.960574882512 24644.023515376386 27097.565780611527 27732.42466582108 23841.492498555737 25803.442845926373 27309.22561384961 1.0888718377340638 1.121410245293863 0.8958228609797992 0.8264591934615816 0.902406529714208 0.9922495117133332 1.0154965599521375 0.8730197199903301 0.9448617551733289 1.0 14.737100784868373 -5.258488342936699 24.9847031960834 0.9271635662840847 1.1051410589021387 0.594773802417509 0.05731904243780929 173.75693785547068 1471080.1383505946 0.01590601332129982 0.03847978361447056 5.514570040501951e-06 5.258488342936699 0.17797749261805396 YSPTSPTYSPT(ph)SPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSPTSPTYSPTSPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YSPT(0.005)S(0.005)PT(0.095)YS(0.326)PT(0.568)SPK 199.38 1.5159e-07 12423000.0 29922.0 34625.0 30039.0 37956.0 39173.0 41128.0 34071.0 33313.0 33411.0 29216.0 True False 34987.20361356136 38062.34117134692 30755.243683541907 35829.44837501232 31497.331855733417 38971.17527829392 30843.548227321175 32438.5690480411 33899.57266759801 34512.62952627125 1.0137507368694947 1.1028525410494614 0.8911301197763214 1.0381546948701401 0.9126320505876676 1.1291859186976407 0.8936887351293489 0.9399043044039469 0.9822367386348647 1.0 15.07483677682302 YSPTSPTYSPT(ph)TPK ddPTM_PC-9_AZD4547_30min_R2 1 YSPTSPTYSPTTPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YSPTSPTYSPT(0.614)T(0.385)PK 143.76 0.00041312 6605100.0 23193.0 16729.0 21534.0 26732.0 26559.0 20277.0 24230.0 27367.0 20894.0 25598.0 True False 30567.89155563127 22136.32209657479 21248.445089934357 20569.35040528294 22871.74129171056 19009.075984551466 26386.42306027035 23138.05898109771 21998.41418405359 24701.821811424816 1.237475186607222 0.8961412751482378 0.8601974887579652 0.8327058045479638 0.9259131357320445 0.7695414585073072 1.0681974496337105 0.9366944332177212 0.8905583706331783 1.0 14.592329827083436 -4.7606018979578115 24.954703269147092 0.9041592927816466 1.2374755838759368 0.6060539489885935 0.07939471328239113 13.56244792159678 403880.4044108523 0.019616467434591937 0.11505320672136884 1.735394041820033e-05 4.7606018979578115 0.3333162910942902 YSPTSPTYSPT(ph)TPK ddPTM_PC-9_Lapatinib_30min_R1 1 YSPTSPTYSPTTPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YSPTSPTYS(0.001)PT(0.911)T(0.088)PK 177.36 0.00021771 6061600.0 42243.0 35720.0 36328.0 37342.0 32867.0 32219.0 27490.0 31859.0 33276.0 30758.0 True False 41640.60707358257 35637.29253463024 33341.2520701353 40088.25524926028 30933.827679008213 30841.068476157332 28913.297690396965 33339.2854469976 29528.106468185542 36074.47931754118 1.154295442688063 0.987880995341259 0.9242337713776272 1.111263585993531 0.8574989373156847 0.8549276125285858 0.8014889816119369 0.9241792557428931 0.8185317439586031 1.0 15.138690951218873 -6.277303801545581 24.693151677581128 0.8675237597246392 1.031795438319302 0.5166500338510136 0.07911965849152486 560.2362822816723 872012.1526844853 0.023838432365197355 0.027123138719374235 5.280757183089079e-07 6.277303801545581 0.16427167859466274 YSPTSPTYSPTS(ph)PK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSPTSPTYSPTSPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YSPTSPT(0.002)YS(0.001)PT(0.053)S(0.943)PK 85.287 0.030592 0.0 8050.1 7739.9 7497.1 10137.0 8689.7 7004.7 5154.8 9870.4 6408.5 7363.4 True False 9412.822933277539 8508.266120782897 7675.859296910085 9569.056754597423 6987.015664533397 6637.3612009304 4666.500026479854 9611.312458553264 6502.212188809124 8698.326131357675 1.0821418731753556 0.9781498178264888 0.8824524605071344 1.1001032394153103 0.8032597949328478 0.7630618926787021 0.5364825319272646 1.1049611515374493 0.7475245341018536 1.0 13.086522086275263 -6.280694436124971 24.06010560190112 0.8135187403614373 0.9992246013733753 0.2555784920290394 0.15316691547313047 713.0287120018963 890960.4672084125 0.04718233323062203 0.0535927820175158 5.239689645842816e-07 6.280694436124971 0.18570586101193798 YSPTSPTYSPTT(ph)PK ddPTM_PC-9_Lapatinib_30min_R1 1 YSPTSPTYSPTTPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YSPTSPTYS(0.001)PT(0.054)T(0.944)PK 127.78 6.781800000000001e-05 8537700.0 75868.0 58326.0 65882.0 63213.0 61543.0 66465.0 63633.0 55770.0 66527.0 59042.0 True False 74786.10840751261 58190.94973053879 60465.43627187443 67861.89489238628 57923.161738193376 63622.44688748247 66927.60538133972 58361.27779839466 59034.0286996328 69247.33103148008 1.0799854275035465 0.8403349105842792 0.8731807474917211 0.9799929308688594 0.8364677869225213 0.9187711055399302 0.9665008655844685 0.8427946164721268 0.8525098053641335 1.0 16.07947084664122 -4.7499178278647385 24.993799409841653 0.8984177005105346 1.0799858288007262 0.4501066956217997 0.059222327275334614 469.39898067575695 1018207.1089152155 0.014259824788286395 0.2219348777029637 1.7786159071559973e-05 4.7499178278647385 0.18156812829019164 YSQANMDAPPLS(ph)PYPFVR ddPTM_PC-9_AZD4547_30min_R2 2 YSQANMDAPPLSPYPFVR 18 0 Q08999 Q08999 RBL2 Retinoblastoma-like protein 2 1 YSQANMDAPPLS(0.994)PY(0.006)PFVR;YSQANMDAPPLS(0.998)PY(0.002)PFVR 128.44 3.7454000000000004e-05 11774100.0 26584.0 24751.5 40767.0 54065.0 43664.0 42127.0 39540.0 48994.0 42266.0 46710.0 True False 35037.159018449594 32751.93833303672 40226.40294331542 41601.149545923334 37602.007295502495 39492.792030438424 43058.9834008704 41423.10307011737 44500.09447225083 45074.69711741748 0.7773132435516855 0.7266147179584912 0.8924386743748387 0.9229379719968895 0.8342154179661156 0.8761632258462335 0.9552805932051802 0.9189879404449934 0.987252212839726 1.0 15.46003017694932 -2.0862081616910615 0.19463889703608264 1.011074823363069 1.3878234856583894e-11 0.7322174047568925 0.04343091701859399 23.55662351501824 0.33862014368031307 0.09026992933559114 6.8856070500411715 0.008199584358434929 2.0862081616910615 -1.0110748233491909 YSQANMDAPPLS(ph)PYPFVR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSQANMDAPPLSPYPFVR 18 0 Q08999 Q08999 RBL2 Retinoblastoma-like protein 2 1 YSQANMDAPPLS(0.953)PY(0.047)PFVR 111.09 0.00018492 6227300.0 31862.0 30853.0 41227.0 46332.0 50044.0 40149.0 41951.0 41177.0 37751.0 33881.0 True False 37255.60729681483 33915.881939626466 42210.00803426816 43736.16825037067 40238.23744385985 38043.51576172491 37977.09758106163 40096.14738063787 38303.03695712465 40023.357098151595 0.9308466355146258 0.8474022270658752 1.0546343708938286 1.0927661101269923 1.0053688736100095 0.9505328518152187 0.9488733663177777 1.0018186950761718 0.957017095372382 1.0 15.288554562928196 -5.257780223596132 24.998852771070577 1.0011569283540998 0.8891244290551078 0.478208785948266 0.046901790612695275 286.10549649166137 1954610.775332122 0.013333039851067834 0.03257424623374034 5.523568909090091e-06 5.257780223596132 -0.11203249929899195 YSQANMDAPPLS(ph)PYPFVR ddPTM_PC-9_Lapatinib_30min_R1 2 YSQANMDAPPLSPYPFVR 18 0 Q08999 Q08999 RBL2 Retinoblastoma-like protein 2 1 YSQANMDAPPLS(0.995)PY(0.005)PFVR;YSQANMDAPPLS(0.976)PY(0.023)PFVR 89.669 0.0012477 10200700.0 40758.0 43865.0 48081.0 43145.0 43498.0 47239.0 37113.0 35946.0 54570.0 30831.0 True False 40176.783445898196 43763.43328755759 44127.96577802729 46318.02722750079 40939.53316035835 45218.69808948745 39034.52954469634 37616.18238732466 48423.75195242475 36160.0972702748 1.1110806241919402 1.2102686826435358 1.220349753160162 1.280915448907718 1.1321743095534331 1.2505137293051263 1.0794918291545763 1.0402677323063185 1.3391488300069154 1.0 15.142110938141995 -7.26524659946479 24.932973197153622 1.1180827430732736 1.2027098105447978 0.160999777124605 0.0961763969540799 622.5366388286573 4076890.303891896 0.03779421506868119 0.026557934015614598 5.429419526850779e-08 7.26524659946479 0.08462706747152415 YSQGDDDGSSSSGGSSVAGSQS(ph)TLFKDSPLR ddPTM_PC-9_AZD4547_30min_R2 2 YSQGDDDGSSSSGGSSVAGSQSTLFKDSPLR 31 1 B0QY68;B0QY66;B0QY69;B0QY65;B0QY67;B0QY63;B0QY64;Q9UH99-3;Q9UH99;Q9UH99-2 B0QY68 SUN2 SUN domain-containing protein 2 1 YSQGDDDGS(0.001)S(0.002)S(0.001)S(0.001)GGS(0.012)S(0.012)VAGS(0.344)QS(0.434)T(0.163)LFKDS(0.03)PLR;YSQGDDDGS(0.002)S(0.002)S(0.001)S(0.001)GGS(0.013)S(0.013)VAGS(0.266)QS(0.326)T(0.326)LFKDS(0.052)PLR 65.954 5.1826e-05 20951000.0 23385.0 34714.0 46048.0 44448.0 48149.0 30071.3 40290.0 45396.0 41716.0 29645.1 True False 30820.94356178316 45934.621630730915 45437.3734327713 34201.200314754446 41464.34246223773 28190.936857239372 43875.73194792786 38381.09129630255 43921.02259509806 28607.234072266183 1.0773828565154118 1.605699506449772 1.5883176023934944 1.1955437645022606 1.4494355643573424 0.9854478341396032 1.533728561002827 1.341656841040491 1.5353117496136446 1.0 14.804092395101952 -5.770059631397716 24.982458423644726 1.3097350944301347 1.4419899540093304 0.06071279229024762 0.22735035724992142 535.5948902612668 1552216.5212027964 0.06189070646130299 0.093420612927177 1.6980104888025642e-06 5.770059631397716 0.1322548595791957 YSQGDDDGSSSSGGSSVAGSQSTLFKDS(ph)PLR ddPTM_PC-9_Lapatinib_30min_R1 2 YSQGDDDGSSSSGGSSVAGSQSTLFKDSPLR 31 1 B0QY68;B0QY66;B0QY69;B0QY65;B0QY67;B0QY63;B0QY64;Q9UH99-3;Q9UH99;Q9UH99-2 B0QY68 SUN2 SUN domain-containing protein 2 1 YSQGDDDGS(0.003)S(0.003)S(0.002)S(0.004)GGS(0.052)S(0.186)VAGS(0.14)QS(0.106)T(0.106)LFKDS(0.397)PLR;YSQGDDDGSSSSGGSSVAGS(0.037)QS(0.026)T(0.01)LFKDS(0.927)PLR 102.81 1.2744e-13 28227000.0 106979.0 127885.0 56392.0 24049.0 30524.0 33083.0 36655.0 33438.0 53274.0 5814.1 True False 105453.45984245434 127588.89013973113 51755.66743941505 25817.64368511222 28728.638332492967 31668.117210239692 38552.816545707574 34991.65155142051 47273.72111990975 6819.059438198726 15.464516888022635 18.7106288332096 7.589854276601885 3.7861004027165404 4.2129913359549365 4.644059418641014 5.653685364545145 5.131448386474785 6.932586751641109 1.0 12.735357044817023 -5.373576969003583 3.8882706771004982 4.748552474807456 17.09295192064187 0.8976177087614535 1.6721832008491222 0.06006752425126582 1.5805746688379505 0.4273086479455587 0.9727185608875326 4.230805214924254e-06 5.373576969003583 12.344399445834414 YSQSAPGS(ph)PVSAQPVIMAVPPRPSSLVAK ddPTM_PC-9_AZD4547_30min_R2 2 YSQSAPGSPVSAQPVIMAVPPRPSSLVAK 29 1 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 Y(0.001)S(0.001)QS(0.004)APGS(0.926)PVS(0.068)AQPVIMAVPPRPSSLVAK;YSQS(0.003)APGS(0.498)PVS(0.498)AQPVIMAVPPRPSSLVAK 75.044 2.6654000000000003e-06 11191100.0 19717.7 22772.0 29032.0 23943.0 27009.0 30131.0 29576.0 34129.0 35667.0 30477.0 True False 25987.518446361864 30132.603669269025 28647.016710828197 18423.311265662494 23259.266559275984 28246.90380680182 32208.206703696076 28855.147256399476 37552.28480437636 29410.009506476832 0.8836283592713138 1.0245696677735878 0.9740566967351505 0.6264299663556795 0.7908622591282639 0.9604520461165146 1.0951443826158238 0.9811335576088419 1.276853881876726 1.0 14.844019630110528 -7.07163987177387 3.4920145904967366 1.0860952815772302 0.8626868286802846 0.4247862587789495 0.12479916343004768 0.26964988757878394 6.3713908788045 0.05329580794502753 0.041484448278583094 8.479302484068382e-08 7.07163987177387 -0.22340845289694566 YSQSAPGS(ph)PVSAQPVIMAVPPRPSSLVAK ddPTM_PC-9_Lapatinib_30min_R1 1 YSQSAPGSPVSAQPVIMAVPPRPSSLVAK 29 1 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 Y(0.001)S(0.001)QS(0.022)APGS(0.785)PVS(0.192)AQPVIMAVPPRPSSLVAK 65.741 9.687299999999999e-05 5984400.0 3855.2 16091.0 13080.0 17912.0 32300.0 37905.0 44438.0 44534.0 39416.0 38221.0 True False 3800.224141042907 16053.74227812809 12004.612890260114 19229.30823268037 30400.1775042433 36283.89151087071 46738.78220319605 46603.21221936003 34976.55501111916 44827.44892371877 0.08477449045805861 0.358123039868857 0.26779603074642777 0.4289628050305111 0.6781598827087878 0.8094123663520018 1.042637565272334 1.0396133025250447 0.7802486166597944 1.0 15.452094779232002 -6.354101060268147 1.1147787193761995 0.9740915576638359 0.2139528991210905 0.9162328126685535 0.09472806095630223 0.12820390095204814 0.33332755430160527 0.04179755742447554 0.0568063020406882 4.4248539408925335e-07 6.354101060268147 -0.7601386585427454 down YSQSAPGSPVS(ph)AQPVIMAVPPRPSSLVAK ddPTM_PC-9_AZD4547_30min_R2 2 YSQSAPGSPVSAQPVIMAVPPRPSSLVAK 29 1 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 YSQS(0.001)APGS(0.221)PVS(0.777)AQPVIMAVPPRPS(0.001)S(0.001)LVAK;YSQSAPGS(0.058)PVS(0.937)AQPVIMAVPPRPS(0.002)S(0.002)LVAK 63.893 0.00044755 21638300.0 54351.0 66812.0 67216.0 66601.0 71445.0 75939.0 82176.0 86661.0 86974.0 77947.0 True False 71633.48742897052 88407.67242013013 66324.67192184582 51247.16842519258 61526.09498046852 71190.52232533677 89489.50480399422 73269.53372166876 91571.26807905981 75218.09925522016 0.9523437595240634 1.1753510564014231 0.8817647956883576 0.6813143237149271 0.8179692865105015 0.9464546835168283 1.1897336637070581 0.9740944592744921 1.2174100247914033 1.0 16.19879222980277 -7.090533591817215 6.188908310250775 1.0919757148260374 0.9015470111641173 0.3184321374676363 0.13460185864537585 0.3288972209654042 18.451678386433194 0.056297990651562886 0.04364444319316831 8.118324528763044e-08 7.090533591817215 -0.1904287036619201 YSQSAPGSPVS(ph)AQPVIMAVPPRPSSLVAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YSQSAPGSPVSAQPVIMAVPPRPSSLVAK 29 1 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 YS(0.001)QS(0.006)APGS(0.229)PVS(0.762)AQPVIMAVPPRPS(0.001)S(0.001)LVAK;YSQS(0.001)APGS(0.036)PVS(0.963)AQPVIMAVPPRPSSLVAK 67.368 0.00025307 21809000.0 27873.0 44064.0 42833.0 47644.0 72159.0 65799.0 101981.0 74993.0 76090.0 74734.0 True False 32591.348383156066 48438.38271116908 43854.301165057106 44974.6611439321 58019.961947715674 62348.384607480584 92320.62140149786 73024.51321165162 77202.67230186242 88282.6826059813 0.36917034486385153 0.548673661485308 0.49674862465139796 0.5094392220120981 0.6572066030964121 0.7062357278578707 1.0457387414646027 0.8271669035882252 0.8744939553596189 1.0 16.429842848355293 -6.745540332107642 1.3595417753627415 0.9261934067434299 0.47848288443748177 0.8618718867393904 0.080390799233557 0.14778405755804666 0.5717645895950229 0.036996990948740864 0.03388911668499029 1.796634222401449e-07 6.745540332107642 -0.4477105223059481 YSQSAPGSPVS(ph)AQPVIMAVPPRPSSLVAK ddPTM_PC-9_Lapatinib_30min_R1 1 YSQSAPGSPVSAQPVIMAVPPRPSSLVAK 29 1 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 YSQS(0.003)APGS(0.26)PVS(0.737)AQPVIMAVPPRPSSLVAK 67.899 7.2374e-05 4387900.0 5389.3 10020.0 15722.0 12112.0 25894.0 27568.0 34920.0 34292.0 33546.0 36217.0 True False 5312.447593723423 9996.79930562697 14429.39784867504 13002.756884447559 24370.96582956272 26388.980904146774 36727.98673512776 35885.331509100775 29767.696224959524 42477.06019388095 0.12506627270049894 0.2353458374943533 0.3396985992630835 0.3061124481095958 0.5737441743455092 0.6212525250970229 0.8646546292866714 0.8448167397957134 0.7007946427810398 1.0 15.374396301283031 -6.420375270514915 0.5997450372706115 0.906325929984226 0.11052593766944667 0.9221816430253439 0.07884466075014906 0.23695962136998636 0.18379977719635743 0.059147645275107574 0.0968922061989277 3.7986101948751363e-07 6.420375270514915 -0.7957999923147794 down YSS(ph)DDTLDR ddPTM_PC-9_AZD4547_30min_R2 1 YSSDDTLDR 9 0 O95171-2;O95171;O95171-3;F2Z2X8 O95171-2 SCEL Sciellin 1 YS(0.228)S(0.766)DDT(0.006)LDR 86.189 0.011855 108920000.0 82809.0 62158.0 87160.0 93070.0 89872.0 90327.0 61174.0 61142.0 49896.0 70089.0 True False 109140.5394657985 82249.35793406032 86004.2014506677 71614.1494171661 77394.82410364135 84678.8384108388 66618.36749025904 51693.90880338643 52533.40069529712 67635.20544343135 1.6136646403341133 1.2160731588647562 1.2715892690323798 1.0588294801153915 1.144297908111963 1.2519935121903694 0.9849658480889399 0.7643047502328078 0.7767168052625336 1.0 16.045486772470767 -1.5228787452803856 0.25707861385436187 0.8450438776127611 5.4169165955148415 0.6964497234634897 0.131916742298862 30.959782788036637 0.4254996015814417 0.1780244955229604 61.77499714258411 0.029999999999996682 1.5228787452803856 4.57187271790208 YSS(ph)DDTLDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSSDDTLDR 9 0 O95171-2;O95171;O95171-3;F2Z2X8 O95171-2 SCEL Sciellin 1 YS(0.095)S(0.905)DDT(0.001)LDR 140.78 0.00075531 10872000.0 69577.0 70352.0 141550.0 116990.0 112390.0 114500.0 109310.0 101830.0 96646.0 116360.0 True False 81355.01189161037 77336.08161982961 144925.0888313641 110435.42958669746 90367.98629836566 108495.41843426987 98955.3654641332 99157.07039780352 98059.26491373111 137455.1468947468 0.5918658830135051 0.5626277616148341 1.054344577888649 0.8034288426555676 0.657436177108471 0.7893150666620566 0.7199102230773944 0.7213776467295969 0.7133910015666258 1.0 17.068601402826467 -11.580052523257915 2.4230923756096248 1.3582186829305485 0.7396921127378115 0.27420106137056854 0.12919748222670546 20006755.549838398 6883844.92605986 39659013.59134791 0.033133934109603407 2.6299499084374443e-12 11.580052523257915 -0.6185265701927369 YSS(ph)DDTLDR ddPTM_PC-9_Lapatinib_30min_R1 2 YSSDDTLDR 9 0 O95171-2;O95171;O95171-3;F2Z2X8 O95171-2 SCEL Sciellin 1 YS(0.042)S(0.957)DDT(0.001)LDR;YS(0.264)S(0.735)DDTLDR 155.53 7.8345e-05 154882000.0 234138.0 216785.0 237065.0 180448.0 198586.0 209555.0 173241.0 176771.0 234192.0 173985.0 True False 230799.14918434917 216283.04765173033 217574.4307973636 193718.74787688203 186905.561915098 200592.82114656418 182210.57130527683 184984.4259942626 207814.8308089108 204058.07542956035 1.1310463881348312 1.059909279240409 1.0662377871561814 0.9493314463007008 0.9159429810442209 0.9830182938082627 0.8929348712208885 0.9065283282950404 1.0184102264585322 1.0 17.63862027962557 -5.713830334911251 3.570315085118013 0.9447966716993099 1.0891634300045527 0.680507170364079 0.0419276466467694 0.12561587299021415 3.272439049319473 0.011667292141100573 0.0206223825962707 1.9327232232523805e-06 5.713830334911251 0.14436675830524281 YSS(ph)PPASTTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSSPPASTTR 10 0 Q08999;F5H837 Q08999 RBL2 Retinoblastoma-like protein 2 1 YS(0.05)S(0.95)PPASTTR 97.59700000000001 0.0050839 7182000.0 42473.0 46678.0 50980.0 57243.0 66143.0 58543.0 59426.0 52865.0 46799.0 43511.0 True False 49662.8400200118 51311.883355844955 52195.55654272666 54035.86029430997 53182.75396149835 55472.90202093854 53796.73907301774 51477.34976509748 47483.34683999035 51399.1998671135 0.9662181541426549 0.9983012087446052 1.0154935617222067 1.0512976940110592 1.0347000361678005 1.0792561394799358 1.046645457752315 1.0015204496993344 0.9238149030092468 1.0 15.649458280666419 -8.022768047014608 6.8826971830038195 0.9616885704043093 1.028768241840373 0.37415348104867885 0.033665020331368485 0.19437763566986294 37.678444491945505 0.022970820771634738 0.009255541018468287 9.489251408217578e-09 8.022768047014608 0.06707967143606364 YSS(ph)PPASTTR ddPTM_PC-9_Lapatinib_30min_R1 1 YSSPPASTTR 10 0 Q08999;F5H837 Q08999 RBL2 Retinoblastoma-like protein 2 1 YS(0.146)S(0.854)PPASTTR 112.85 0.0013925 7909300.0 54544.0 51248.0 66046.0 52414.0 62537.0 61125.0 52008.0 55218.0 64262.0 40931.0 True False 53766.19255785547 51129.338404667724 60615.95282493264 56268.70040797838 58858.69661247252 58510.82623933441 54700.71976290161 57783.62986321964 57024.13685114015 48005.868812870765 1.1199920736241382 1.0650643279464933 1.2626779667547858 1.1721212801567353 1.2260729379132083 1.218826524469591 1.1394590102332633 1.2036784520755799 1.1878576153558025 1.0 15.550923168501063 -10.19979432695414 7.3618933632647 1.0000078999931579 1.1786809145618862 0.48893157823765854 0.054366131753467876 7.94186001121946e-11 0.0 0.054361762388905624 0.013184664019069847 6.312562238294444e-11 10.19979432695414 0.1786730145687283 YSS(ph)PTAGSAK ddPTM_PC-9_AZD4547_30min_R2 2 YSSPTAGSAK 10 0 P28749;P28749-2 P28749 RBL1 Retinoblastoma-like protein 1 1 Y(0.003)S(0.136)S(0.851)PT(0.01)AGSAK;Y(0.001)S(0.384)S(0.576)PT(0.04)AGSAK 115.0 0.0011604 54600000.0 131871.0 112536.0 192955.0 212250.0 200628.0 180201.0 200676.0 209150.0 167397.0 187990.0 True False 173803.23491280308 148911.0612385763 190396.29062544278 163319.04172981108 172774.26529136315 168933.0029832894 218535.77523907603 176830.67328887322 176245.26367225114 181408.52731970284 0.9580764337858457 0.8208603169802758 1.0495443264907856 0.900283157262988 0.9524043210321462 0.9312296697363769 1.2046609851693602 0.9747649457361952 0.9715379220385142 1.0 17.468882747462565 YSS(ph)PTAGSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 YSSPTAGSAK 10 0 P28749;P28749-2 P28749 RBL1 Retinoblastoma-like protein 1 1 Y(0.141)S(0.153)S(0.698)PT(0.005)AGS(0.002)AK;YS(0.021)S(0.974)PT(0.004)AGS(0.001)AK;YS(0.41)S(0.573)PT(0.015)AGS(0.002)AK 98.898 0.0045817 37873800.0 173868.0 190054.0 248943.0 268332.0 295210.0 274679.0 296993.0 303245.0 250502.0 212747.0 True False 203300.41835046795 208921.3050968711 254878.74524158504 253298.22798408128 237365.71968271615 260274.3496952559 268859.6729968832 295285.14006463566 254165.11784677568 251316.34699567463 0.8089422784502233 0.8313080609136294 1.0141749563388796 1.0078860010982125 0.9444897736270272 1.035644329573736 1.0698057496495066 1.1749539717355424 1.0113353981352835 1.0 17.939144989517573 -4.268723236639536 0.5188235140994953 1.0688904797175705 0.4155430995348162 0.6703695311953084 0.05859432374870827 4.121254839234014 0.5728287456613345 0.03494780715652172 1.8290308352058642 5.386129156629275e-05 4.268723236639536 -0.6533473801827543 YSS(ph)PTAGSAK ddPTM_PC-9_Lapatinib_30min_R1 2 YSSPTAGSAK 10 0 P28749;P28749-2 P28749 RBL1 Retinoblastoma-like protein 1 1 Y(0.003)S(0.326)S(0.669)PT(0.002)AGSAK;Y(0.001)S(0.042)S(0.911)PT(0.047)AGSAK 119.03 0.0008238999999999999 65575000.0 147782.0 116650.0 130611.0 128101.0 117618.0 112143.0 106028.0 102108.0 121119.0 84401.0 True False 145674.60158010063 116379.90409195477 119872.66775304 137521.97487240908 110699.94048588512 107346.90530810122 111517.61104101161 106852.3104435807 107477.3027803872 98989.60039273664 1.4716152101043283 1.1756780877003534 1.210962235198958 1.389256793913674 1.118298690435038 1.0844260900357954 1.126558856673536 1.0794296574554207 1.085743374596685 1.0 16.594989346661777 -1.5228788156649327 0.18568934876451829 0.9820915128598355 2.7575054264156047 0.6498182161650086 0.0829869421004713 37.464714239808906 0.43121835114990464 0.18241699951825965 18.931729105435323 0.02999999513800481 1.5228788156649327 1.7754139135557692 YSS(ph)QDADEQDWEFQKR ddPTM_PC-9_AZD4547_30min_R2 3 YSSQDADEQDWEFQKR 16 1 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 Y(0.015)S(0.227)S(0.759)QDADEQDWEFQKR;Y(0.011)S(0.233)S(0.756)QDADEQDWEFQKR;YS(0.134)S(0.866)QDADEQDWEFQKR 122.16 9.2464e-05 37329300.0 45044.0 36858.4 55062.0 79098.0 72927.0 63259.0 44551.0 63956.0 51005.0 58852.0 True False 59367.05502659657 48772.1569947034 54331.84190312833 60863.17815191794 62802.34486165052 59303.4047298289 48515.9526932771 54073.06976267353 53701.02017122871 56791.60939315463 1.0453490517518662 0.8587915981930625 0.9566878361731586 1.0716931392202116 1.1058384422051684 1.0442282823732942 0.8542802926645879 0.9521313155318191 0.9455801789216693 1.0 15.79339017580991 -9.92094487658601 8.65899212946758 1.0000119673504837 0.9808056269842016 0.004521665239919592 0.08100792023728738 0.0 0.0 0.0851360266601837 0.020648519439137564 1.1996515608819045e-10 9.92094487658601 -0.019206340366282104 YSS(ph)QDADEQDWEFQKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSSQDADEQDWEFQKR 16 1 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 Y(0.005)S(0.28)S(0.715)QDADEQDWEFQKR 50.943999999999996 0.041666 8255200.0 5830.4 8389.2 7391.8 8216.4 8453.8 6581.9 11292.0 9719.0 7392.0 6950.1 True False 6817.371564350919 9222.024333708698 7568.048545557611 7756.06174592821 6797.338576111077 6236.73357722726 10222.340012999632 9463.886548131706 7500.094015709929 8210.098113038677 0.8303642015585743 1.1232538523581044 0.9217975767595993 0.9446978147082798 0.8279241590689447 0.7596417839785052 1.2450935265639833 1.152712966133968 0.9135206318422466 1.0 13.00318374738972 -7.260813359230253 24.99999160114619 1.0905578560944302 0.9109414385727929 0.329314476640304 0.12243264361538818 70.96397112439878 2834025.6835299986 0.050449231622029425 0.03671528072057624 5.485126410135525e-08 7.260813359230253 -0.17961641752163737 YSS(ph)QDADEQDWEFQKR ddPTM_PC-9_Lapatinib_30min_R1 2 YSSQDADEQDWEFQKR 16 1 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 Y(0.001)S(0.184)S(0.814)QDADEQDWEFQKR;YS(0.151)S(0.849)QDADEQDWEFQKR 113.81 9.3409e-05 31429000.0 46654.0 32099.0 48314.0 39853.0 42145.0 37720.0 40478.0 32796.0 54160.0 47684.0 True False 45988.70540470425 32024.676737656693 44341.809417433265 42783.922565710716 39666.113960258 36106.803529614655 42573.7527796249 34319.82188768428 48059.930469916115 55926.115865063875 0.822311807164721 0.5726247253595164 0.7928640981329594 0.7650079377752234 0.7092592315182891 0.6456161485759461 0.7612499477407838 0.6136636052196021 0.8593468315567104 1.0 15.77123451647414 -8.516389536609116 4.957111564864634 0.9997342568410804 0.7104429118503203 0.6009404326618433 0.07588545383660608 0.09302957374087259 8.389106022128567 0.06851365566563179 0.01782740847475379 3.0451624327256574e-09 8.516389536609116 -0.28929134499076015 YSS(ph)SQPEPR ddPTM_PC-9_Lapatinib_30min_R1 1 YSSSQPEPR 9 0 E7EPP6;O14757-2;O14757-3;O14757 E7EPP6 CHEK1 Serine/threonine-protein kinase Chk1 1 YS(0.043)S(0.804)S(0.153)QPEPR 76.843 0.023925 3072700.0 13534.0 15469.0 17701.0 15926.0 17047.0 14038.0 14004.0 13964.0 20389.0 13598.0 True False 13341.002678168372 15433.18248091252 16245.692107835963 17097.251167578586 16044.328975691511 13437.627464176303 14729.058597901754 14612.818418088274 18092.576114311665 15948.396181803922 0.836510613737423 0.9676949522059636 1.0186411174291767 1.0720357691568656 1.0060152000736626 0.8425692032599339 0.9235448147887527 0.916256296339098 1.134444862547001 1.0 13.961123729126026 -8.25184750688842 24.963614067704807 1.0672224351336843 0.9526768309887337 0.27862913727360017 0.07648496302903303 848.7889236417215 2209054.4789836165 0.05669065234235487 0.020844970509473634 5.599541827774156e-09 8.25184750688842 -0.11454560414495063 YSS(ph)YQGSR ddPTM_PC-9_AZD4547_30min_R2 4 YSSYQGSR 8 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-5 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 YS(0.006)S(0.994)YQGSR;YS(0.003)S(0.997)YQGSR;YS(0.041)S(0.959)YQGSR;YS(0.159)S(0.84)YQGSR 153.1 0.00010118 45469300.0 101557.0 99423.0 141274.0 198252.0 165584.0 163129.0 106509.0 165621.0 120399.0 127126.0 True False 133850.01348317324 131559.5404272674 139400.6144532082 152548.06436286663 142595.5197878915 152928.51784208222 115988.0946647272 140028.08004196276 126763.04534056988 122675.35743414311 1.0910912858356996 1.0724202739567616 1.136337544629074 1.243510249764386 1.1623811234007801 1.246611552969635 0.945488132993573 1.1414523908531122 1.0333211819547474 1.0 16.904485949370276 -7.259171415234853 24.999756065746684 1.0418531280092374 1.157804783313712 0.44684391553224434 0.0696317284848358 220.45354216103325 2430069.7805582676 0.028676143959189458 0.021102839298489846 5.505903365172445e-08 7.259171415234853 0.1159516553044746 YSS(ph)YQGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YSSYQGSR 8 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-5 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 YS(0.036)S(0.964)YQGSR;YS(0.128)S(0.872)YQGSR;YS(0.046)S(0.954)YQGSR;YS(0.042)S(0.958)YQGSR 153.1 0.00010118 49113000.0 163454.0 161286.0 207657.0 181705.0 208027.0 155252.0 138019.0 135420.0 145320.0 114532.0 True False 191123.53383634295 177297.40817795985 212608.33042355764 171524.65794555825 167265.60268431442 147110.31181447415 124944.8411489724 131865.36848935043 147445.03008156994 135295.7449651868 1.4126352154350552 1.3104433419068764 1.5714339758302396 1.2677757012217463 1.2362961061883642 1.0873240089873288 0.92349423983084 0.9746453484053097 1.089797983813233 1.0 17.045756941880207 -6.53945600405173 1.4813130172249418 0.9941560583422202 1.4124534478085358 0.8340516325888157 0.08063148490219822 0.1510283883043375 0.6801267060257529 0.03317403346762837 0.036189628706572635 2.887646295689698e-07 6.53945600405173 0.41829738946631556 YSS(ph)YQGSR ddPTM_PC-9_Lapatinib_30min_R1 4 YSSYQGSR 8 0 Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-4;Q5VWV2;Q8TEW0-6;Q8TEW0-7;Q8TEW0-3;Q8TEW0-5 Q8TEW0-11 PARD3 Partitioning defective 3 homolog 1 YS(0.019)S(0.981)YQGSR;YS(0.038)S(0.962)YQGSR;YS(0.224)S(0.775)YQGSR;YS(0.004)S(0.996)YQGSR 133.75 0.0034688 42033700.0 136104.0 124295.0 152055.0 119299.0 115906.0 114131.0 97467.0 100931.0 123205.0 81237.8 True False 134163.132001583 124007.20256416203 139553.62484927362 128072.64642979774 109088.63695996364 109249.8831823555 102513.36435030641 105620.62272673089 109328.35549383343 95279.6454874356 1.4080985641290502 1.3015078081972367 1.4646740564087886 1.3441763534551197 1.1449311802314484 1.146623527233444 1.075920925459622 1.1085329105329107 1.1474471271857367 1.0 16.53988042484142 -6.2746577530678715 2.902557311368703 1.1038969927499194 1.3867322925053653 0.8638575317143788 0.05408212619149639 0.0922995191515174 1.568052017270311 0.016908393337414424 0.020964762748412108 5.313029740322875e-07 6.2746577530678715 0.28283529975544597 YSSPPAST(ph)TR ddPTM_PC-9_AZD4547_30min_R2 1 YSSPPASTTR 10 0 Q08999;F5H837 Q08999 RBL2 Retinoblastoma-like protein 2 1 YS(0.016)S(0.383)PPAS(0.035)T(0.566)T(0.001)R 87.713 0.025554 9665600.0 39123.0 51690.0 60727.0 87553.0 62588.0 58633.0 40265.0 53398.0 44163.0 54034.0 True False 51563.300191047376 68397.78164695733 59921.72030168306 67369.00853036575 53898.73654751993 54966.66924112078 43848.506996359254 45146.566063969614 46497.366019448564 52142.286106669584 0.9888960389186283 1.3117526436611011 1.1491962623023235 1.2920225322024863 1.0336857198255003 1.054166845095231 0.8409394806099715 0.865834036728107 0.8917400730057562 1.0 15.670166216785262 -6.805706402393497 1.7283144104111972 0.8917199337703788 1.1877920746247195 0.6004092450468732 0.09906558471647742 0.21887959012106695 1.3510928051768554 0.040422168546945324 0.03565355188441194 1.5642047400455253e-07 6.805706402393497 0.29607214085434064 YSSPT(ph)AGSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSSPTAGSAK 10 0 P28749;P28749-2 P28749 RBL1 Retinoblastoma-like protein 1 1 YS(0.023)S(0.267)PT(0.623)AGS(0.087)AK 102.95 0.0073762 18822000.0 125620.0 124730.0 164800.0 177140.0 212710.0 176320.0 198990.0 202110.0 193240.0 149020.0 True False 146884.98489190527 137112.37008814747 168729.45700748026 167215.42009562821 171031.00245151125 167073.46880637962 180140.2266371592 196804.82665324607 196065.769425837 176036.14635832942 0.8344024107010065 0.7788875916940895 0.9584932441319406 0.9498925280678081 0.971567521725737 0.9490861522626957 1.023313849818524 1.1179796350042852 1.1137813084520516 1.0 17.425512169308604 -5.592250662402477 0.4673610198194381 1.0785627956915833 0.7214608475799594 0.7380163901970304 0.051744286566691305 1.2482387613187134 0.36305968221138507 0.04277332304115707 0.22872126716414876 2.5571095701074476e-06 5.592250662402477 -0.3571019481116239 YSSS(ph)SIPEPFGSR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSSSSIPEPFGSR 13 0 Q8WUF5;K7EN03 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 YSS(0.008)S(0.61)S(0.382)IPEPFGSR 131.79 6.3973e-05 3358500.0 13982.0 14650.0 20599.0 24105.0 24908.0 19221.0 21479.0 15715.0 18208.0 15421.0 True False 16348.876442912084 16104.355181522944 21090.158282142518 22754.474999464415 20027.45620357409 18213.01692336334 19444.35362550649 15302.49790141885 18474.25755384826 18216.705227431157 0.8974661575076457 0.8840432438502993 1.1577372537369954 1.24909936870473 1.099400575105989 0.999797531769781 1.0673913522093288 0.8400255540379484 1.0141382496561053 1.0 14.152974428597284 -7.71802124554349 24.998570650090443 0.9453109871046501 1.055957181036765 0.13909864486216472 0.11239306355248878 262.77806652212473 151297.69601344963 0.058471155328384976 0.03375804752995265 1.9141622825401207e-08 7.71802124554349 0.11064619393211483 YSSSGS(ph)PANSFHFK ddPTM_PC-9_Lapatinib_30min_R1 2 YSSSGSPANSFHFK 14 0 O00418;H3BRH4 O00418 EEF2K Eukaryotic elongation factor 2 kinase 1 Y(0.001)S(0.001)S(0.008)S(0.393)GS(0.597)PANSFHFK;YS(0.11)S(0.11)S(0.11)GS(0.668)PANS(0.003)FHFK 127.2 0.00060999 5848300.0 40356.3 28444.3 74054.0 32062.5 43456.6 51563.0 32986.0 43498.6 59227.0 29619.2 True False 39780.81176156096 28378.43897096259 67965.5659767067 34420.48320736455 40900.56822696284 49357.77068922378 34693.85367826243 45519.7037554465 52556.231572040655 34738.83925489682 1.1451393487752595 0.8169080942151036 1.9564719902702623 0.9908357315799666 1.177372908946503 1.4208238314199362 0.9987050351249704 1.3103403778532985 1.512895442084533 1.0 15.08426192895812 -10.657136348425729 4.557815418626302 0.9999711505275035 1.254704007362396 0.06045670041325313 0.30571948514977254 210609931.04911146 2.4895400794594846 63766.35708337463 0.07142232389538045 2.2022349543601163e-11 10.657136348425729 0.25473285683489255 YSSSVSEQDSGLDGMPGS(ph)PPPSQPDPEHLDKPK ddPTM_PC-9_Lapatinib_30min_R1 1 YSSSVSEQDSGLDGMPGSPPPSQPDPEHLDKPK 33 1 O94885 O94885 SASH1 SAM and SH3 domain-containing protein 1 1 YSSSVSEQDSGLDGMPGS(0.938)PPPS(0.062)QPDPEHLDKPK 74.36399999999999 3.9575999999999997e-08 5149800.0 30208.0 28644.0 30071.0 32192.0 34710.0 38877.0 38377.0 34539.0 41192.0 31780.0 True False 29777.228380531247 28577.676577882117 27598.678457416805 34559.50706936389 32668.426042485615 37214.321336713365 40363.973279896825 36143.80803081861 36552.52318901009 37273.1306558118 0.7988926032401371 0.7667098543928226 0.7404443354186963 0.9271962526704263 0.87646048152362 0.9984222060754302 1.0829241485676784 0.9697014282105358 0.9806668381720882 1.0 15.185848378973875 -6.198369457650622 1.2167377397799326 1.0085805195185784 0.7657995749805265 0.8098112879086589 0.04722336975270249 0.19377714160159992 0.586761610096115 0.019341422523751085 0.02997752545064969 6.333307027280469e-07 6.198369457650622 -0.24278094453805188 YSVDIPLDK ddPTM_PC-9_Lapatinib_30min_R1 2 YSVDIPLDK 9 0 K7ELC7;P61353 K7ELC7 RPL27 60S ribosomal protein L27 0 ; 115.71 0.0090405 27296000.0 194625.0 192432.0 220286.0 195313.0 202938.0 188020.0 201760.0 177946.0 201335.0 187533.0 False True 191849.6118101458 191986.43552698637 202174.93540855023 209676.9695650681 191001.58583145923 179978.82289602736 212206.14558073826 186214.02078381146 178658.53214845946 219947.82917798503 0.87225053562542 0.8728726091296319 0.9191949571138858 0.9533032008031069 0.8683949577738179 0.8182796055258442 0.9648021822894097 0.8466281366801958 0.8122768604544233 1.0 17.746801836768682 YSVGS(ph)LSPVSASVLKK ddPTM_PC-9_Lapatinib_30min_R1 2 YSVGSLSPVSASVLKK 16 1 Q9UBU7 Q9UBU7 DBF4 Protein DBF4 homolog A 1 Y(0.017)S(0.018)VGS(0.481)LS(0.481)PVS(0.002)ASVLKK;Y(0.002)S(0.003)VGS(0.91)LS(0.084)PVS(0.001)ASVLKK 58.01 0.025327000000000002 12892900.0 54785.0 46842.0 67066.0 56861.0 48045.0 49394.0 44315.0 40819.0 59717.0 39690.0 True False 54003.75585366146 46733.540226963894 61552.09236224653 61042.747622735485 45219.087560104344 47281.533763037776 46609.41386503968 42715.59975708578 52991.042612111945 46550.36361639932 1.1601145868307754 1.0039350199726482 1.3222687768772277 1.3113269775025047 0.9714013822262394 1.015707077020143 1.001268523896547 0.9176211835655225 1.1383593702680257 1.0 15.506504816625188 -6.278224710518894 24.824559052397653 1.0033834595797444 1.1942242808705386 0.4836748357423992 0.09708049980700238 689.6865817991496 1020004.9570473096 0.031527097373701775 0.03584260434127041 5.269571352984638e-07 6.278224710518894 0.19084082129079416 YSVGSLS(ph)PVSASVLK ddPTM_PC-9_AZD4547_30min_R2 2 YSVGSLSPVSASVLK 15 0 Q9UBU7 Q9UBU7 DBF4 Protein DBF4 homolog A 1 YSVGS(0.032)LS(0.958)PVS(0.01)ASVLK;YSVGS(0.309)LS(0.688)PVS(0.003)ASVLK 172.09 0.00010815 25885000.0 65801.0 64011.0 84228.0 104441.0 93874.0 84166.0 79332.0 88499.0 71540.0 84532.0 True False 86724.34925417569 84701.30394667042 83111.08168640253 80363.74104736472 80841.21548318975 78903.08671478828 86392.39431355215 74823.51305470719 75321.45834819539 81572.56040953849 1.0631559046175874 1.0383553430396686 1.01886076971398 0.9851810540688579 0.9910344247786634 0.9672748571168049 1.0590864609350925 0.9172632644979215 0.9233675879491929 1.0 16.315796315832998 -3.8802662875086926 0.3828212912911268 0.9628488174928945 1.2399351360254884 0.40784095711829926 0.03711514587450562 12.178882803550037 0.8289386647353904 0.03137412691622389 1.7774550017229045 0.00013174486976515458 3.8802662875086926 0.2770863185325939 YSVGSLS(ph)PVSASVLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YSVGSLSPVSASVLK 15 0 Q9UBU7 Q9UBU7 DBF4 Protein DBF4 homolog A 1 YSVGS(0.233)LS(0.743)PVS(0.023)ASVLK 118.71 0.00010865 10136000.0 30665.0 43251.0 41363.0 39640.0 47764.0 37815.0 39918.0 41055.0 32310.0 32428.0 True False 35855.97883864247 47544.67344409891 42349.250790051046 37419.09931461399 38404.98707674294 35831.91483049711 36136.67805870698 39977.349751368165 32782.47262548534 38306.93970009324 0.9360178369601057 1.241150397717184 1.1055242502169385 0.9768229884081007 1.0025595199568882 0.9353896476990016 0.9433454706020024 1.0436059383587581 0.855784170757069 1.0 15.225318154571164 -5.7718760550032435 5.525558789862034 0.9658446959040314 1.109984656862238 0.3298652955799617 0.08342216377924604 0.16754790651984058 15.950389486172519 0.022175051837493572 0.035546304283587286 1.6909234420261334e-06 5.7718760550032435 0.14413996095820658 YSVGSLS(ph)PVSASVLK ddPTM_PC-9_Lapatinib_30min_R1 2 YSVGSLSPVSASVLK 15 0 Q9UBU7 Q9UBU7 DBF4 Protein DBF4 homolog A 1 YSVGS(0.077)LS(0.921)PVS(0.001)ASVLK;YSVGSLS(0.984)PVS(0.016)ASVLK 204.23 8.9601e-13 16216700.0 48521.0 57482.0 68994.0 67766.0 65765.0 54861.0 56755.0 56386.0 60537.0 49437.0 True False 47829.081642338344 57348.903960683565 63321.57964454184 72749.73770074893 61896.83199896473 52514.72291723723 59693.49619565222 59005.899407213234 53718.685577129145 57982.119579338185 0.8248936394416002 0.9890791226114427 1.0920880454861184 1.2546926229767073 1.0675158557160016 0.9057054708974583 1.0295155925435309 1.017656819642031 0.9264698490993367 1.0 15.823320452698798 -6.7195436619889835 24.99655116869323 0.980325798869452 1.0567038300145488 0.09320117165642339 0.10561560641311538 374.27507743165825 223305.43292776519 0.037895542867223506 0.037895185907251216 1.9074639466133927e-07 6.7195436619889835 0.07637803114509678 YSVGSLS(ph)PVSASVLKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YSVGSLSPVSASVLKK 16 1 Q9UBU7 Q9UBU7 DBF4 Protein DBF4 homolog A 1 Y(0.001)S(0.039)VGS(0.127)LS(0.833)PVSASVLKK;YS(0.015)VGS(0.122)LS(0.848)PVS(0.013)AS(0.001)VLKK 78.501 0.0044535 16255200.0 49592.0 38739.0 48129.0 57010.0 61564.0 62423.0 62897.0 65102.0 59670.0 46492.0 True False 57986.9461133526 42584.7519028681 49276.57789024893 53815.91452891376 49500.97614087184 59149.42799058894 56938.94082515395 63393.14148127079 60542.560865450636 54920.63156953052 1.0558317422103944 0.7753871484335542 0.8972325423436526 0.9798852087267393 0.9013184066938981 1.0769983210354144 1.0367495638331874 1.1542682534707185 1.1023646148133357 1.0 15.745060595657016 -6.765520191676889 24.123577426418905 1.0813850561634721 0.9156372082008961 0.4957760948856972 0.07640900193589649 53.20626367646941 314523.6347543066 0.026012680516511053 0.02379521997576148 1.715851933069534e-07 6.765520191676889 -0.16574784796257602 YSVLNNDDYFADVS(ph)PLR ddPTM_PC-9_AZD4547_30min_R2 5 YSVLNNDDYFADVSPLR 17 0 Q1ED39;H3BMC9 Q1ED39 KNOP1 Lysine-rich nucleolar protein 1 1 YSVLNNDDYFADVS(1)PLR;YSVLNNDDYFADVS(1)PLR;YSVLNNDDY(0.014)FADVS(0.986)PLR;YSVLNNDDYFADVS(1)PLR;YSVLNNDDYFADVS(1)PLR 181.6 6.0195e-08 19066800.0 34590.9 41064.1 46094.4 62045.0 54323.5 51701.600000000006 42150.0 61328.5 48368.299999999996 47211.8 True False 45590.086664583505 54337.26727275733 45483.158138454084 47741.4838356943 46781.61971686579 48468.69077885716 45901.268344630385 51851.58951373007 50924.94959215848 45558.92925215351 1.0006838925528199 1.1926809555162863 0.998336854817635 1.0479061869839188 1.0268375592838255 1.0638680841377788 1.0075142040889975 1.1381213378995099 1.1177819678400658 1.0 15.475446220081846 -7.762998055458524 24.999985021442487 1.0959637262496935 1.0516581894819579 0.058583700034515074 0.0628643168768419 104.43531533843748 1674966.6698147713 0.031038511831422484 0.01616990746584557 1.7258456193987143e-08 7.762998055458524 -0.04430553676773563 YSVLNNDDYFADVS(ph)PLR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YSVLNNDDYFADVSPLR 17 0 Q1ED39;H3BMC9 Q1ED39 KNOP1 Lysine-rich nucleolar protein 1 1 YSVLNNDDYFADVS(1)PLR;YSVLNNDDYFADVS(1)PLR;YSVLNNDDYFADVS(1)PLR;YSVLNNDDYFADVS(1)PLR 126.43 5.2858999999999997e-05 0.0 14785.8 15596.099999999999 15752.2 15506.9 18465.5 13726.100000000002 14721.4 13183.7 13121.900000000001 9463.8 True False 17288.743907138425 17144.377736965882 16127.792188551175 14638.09866704812 14847.31783070088 13006.279152581945 13326.882418293737 12837.641844284806 13313.78296330413 11179.512024600417 1.546466775034071 1.5335533160338153 1.442620407139606 1.309368301124156 1.3280828177499597 1.163403118486902 1.1920808698061285 1.1483186221398294 1.1909091321702832 1.0 13.448569596795553 -2.358881514868006 0.1858771220623758 0.9810479520008081 3.102194199926485 0.9405851306602117 0.041481856134222395 8.684898061003864 0.131150494642489 0.09116424292413462 4.9291109734384095 0.004376414871414776 2.358881514868006 2.121146247925677 YSVLNNDDYFADVS(ph)PLR ddPTM_PC-9_Lapatinib_30min_R1 3 YSVLNNDDYFADVSPLR 17 0 Q1ED39;H3BMC9 Q1ED39 KNOP1 Lysine-rich nucleolar protein 1 1 YSVLNNDDYFADVS(1)PLR;YSVLNNDDYFADVS(1)PLR;YSVLNNDDYFADVS(1)PLR 219.96 1.0051000000000001e-22 3425300.0 24349.0 27680.6 24608.2 24387.0 29544.4 25119.0 24222.0 22317.3 26861.4 23123.600000000002 True False 24001.778794940263 27616.507271390994 22585.008786398994 26180.501332647178 27806.656478525267 24044.718925248937 25476.09664084376 23354.243231309185 23835.986268918114 27120.48344973978 0.8850055656058211 1.0182896378882942 0.832765714824147 0.9653405102886682 1.0253009143460556 0.8865888755194608 0.9393673489654626 0.8611293111566294 0.8788923808490154 1.0 14.727095275734824 -9.591874132369188 7.385617339120223 0.9999999986637307 0.9237300910113221 0.12572995623603955 0.06190068283673916 3698033.738451541 457402.1341244771 0.059416377865944565 0.014854094464479417 2.559327526113982e-10 9.591874132369188 -0.0762699076524086 YSYLTEPGMS(ph)PQSPCER ddPTM_PC-9_AZD4547_30min_R2 4 YSYLTEPGMSPQSPCER 17 0 Q12955-6;Q12955-5;Q12955-4;H0Y3A4;H0YA66 Q12955-6 ANK3 Ankyrin-3 1 YSYLT(0.001)EPGMS(0.927)PQS(0.073)PCER;YSYLTEPGMS(0.975)PQS(0.024)PCER;YSYLT(0.001)EPGMS(0.513)PQS(0.486)PCER;YSYLTEPGMS(0.661)PQS(0.339)PCER 112.03 0.00025266 46940600.0 136922.0 133440.0 205949.0 251295.0 205316.0 193903.0 151534.0 198580.0 160745.0 180754.0 True False 180460.3478454771 176571.87043857604 203217.98169531397 193362.8202190475 176811.4174121332 181778.2147572363 165020.2324397447 167894.0239144368 169241.65253257836 174425.8574772357 1.0345963061642336 1.0123032960386646 1.1650679815166507 1.1085674051754815 1.0136766415794105 1.042151762280774 0.9460766587389801 0.9625523780861943 0.9702784608908462 1.0 17.412254400382913 -6.865386973698607 1.6890072018635307 0.967836828498912 1.077455191801261 0.5169200767734246 0.044517004146712044 0.3059409590417116 1.7966518596983891 0.021203369567428753 0.0178238954615314 1.3633677801545068e-07 6.865386973698607 0.10961836330234898 YSYLTEPGMS(ph)PQSPCER ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 YSYLTEPGMSPQSPCER 17 0 Q12955-6;Q12955-5;Q12955-4;H0Y3A4;H0YA66 Q12955-6 ANK3 Ankyrin-3 1 YSYLT(0.001)EPGMS(0.935)PQS(0.064)PCER;YSYLTEPGMS(0.584)PQS(0.416)PCER;YSYLTEPGMS(0.953)PQS(0.047)PCER 135.55 2.7870999999999998e-05 18745800.0 44078.0 41613.9 59701.0 63585.0 127507.0 133705.0 145976.0 130168.0 121613.0 113410.0 True False 51539.53481981682 45745.05297531592 61124.49825730335 60022.53859535138 102522.9186666579 126693.2744257996 132148.096505281 126751.22792439656 123391.3600558077 133970.33524693424 0.384708560479595 0.3414565835861991 0.4562539770064666 0.4480285765107461 0.7652658215543581 0.9456815510111134 0.9863981922692476 0.9461141355716441 0.9210349427608182 1.0 17.03155405773157 -6.378022982626976 1.8637131366913842 0.9636964661229421 0.3848744814612196 0.9843356227101049 0.032950766531789195 0.039007826777587365 0.2680690093533179 0.012209569604117019 0.014734336536374694 4.187714033773983e-07 6.378022982626976 -0.5788219846617225 down YSYLTEPGMS(ph)PQSPCER ddPTM_PC-9_Lapatinib_30min_R1 3 YSYLTEPGMSPQSPCER 17 0 Q12955-6;Q12955-5;Q12955-4;H0Y3A4;H0YA66 Q12955-6 ANK3 Ankyrin-3 1 YSYLTEPGMS(0.991)PQS(0.009)PCER;YSYLTEPGMS(0.638)PQS(0.362)PCER;YSYLT(0.002)EPGMS(0.61)PQS(0.387)PCER 156.29 3.5839e-17 13397600.0 40943.1 46567.0 53119.0 43718.0 88751.0 141028.0 121882.0 128365.0 153657.0 119811.0 True False 40359.24388595503 46459.17697256797 48751.76086526966 46933.16755897277 83530.84067117958 134996.56119232482 128192.45358679391 134329.30651947155 136350.53058005718 140520.17171187783 0.28721316942814096 0.33062283091873623 0.346937811641948 0.33399594511743413 0.5944402120604505 0.9606916896537915 0.9122708293414227 0.9559432278157187 0.9703270990846063 1.0 17.100417719045424 -6.559703460826745 2.2795499873556855 0.9612506374680332 0.32266148629375435 0.9896806942948516 0.03062265641127191 0.028237918565727004 0.2967346391609059 0.01149811563070053 0.01207147763202101 2.756109951285818e-07 6.559703460826745 -0.6385891511742788 down YT(ph)PSQQGVAFNSGAK ddPTM_PC-9_AZD4547_30min_R2 1 YTPSQQGVAFNSGAK 15 0 G3V3A4;Q13573;G3V4X8 G3V3A4 SNW1 SNW domain-containing protein 1 1 Y(0.003)T(0.577)PS(0.419)QQGVAFNSGAK 101.3 0.0041566 4251400.0 11058.0 11615.0 16423.0 19247.0 18552.0 21250.0 17349.0 22261.0 19904.0 21140.0 True False 14574.213979311455 15369.321606295427 16205.22028940242 14809.901513185732 15976.375030830028 19921.23414073674 18893.02739053365 18821.073956890275 20956.084805178656 20399.89503451522 0.7144259298713492 0.7534019944853438 0.7943776309625271 0.7259792998017096 0.7831596684100139 0.9765361099668102 0.9261335589505705 0.9226064117019384 1.027264344729343 1.0 14.316274108531811 -6.710603023608305 4.781132125103892 0.9634875116165212 0.7517848396063979 0.9011262340659316 0.03586864080702749 0.06129038870877653 2.9635148567385077 0.012249175326771635 0.011950110248653759 1.947139093599619e-07 6.710603023608305 -0.21170267201012338 YT(ph)PSQQGVAFNSGAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YTPSQQGVAFNSGAK 15 0 G3V3A4;Q13573;G3V4X8 G3V3A4 SNW1 SNW domain-containing protein 1 1 Y(0.008)T(0.801)PS(0.191)QQGVAFNSGAK 104.78 0.0036626999999999996 0.0 16705.0 16205.0 16982.0 15421.0 17331.0 11567.0 14505.0 12846.0 13255.0 8834.1 True False 19532.826561210586 17813.725304885967 17386.915284593648 14557.011365556551 13935.114961624478 10960.40615746027 13130.981392894055 12508.806111462078 13448.829299003663 10435.652399302882 1.8717398600316937 1.7070063876481696 1.6661071698550558 1.394930648181515 1.335337210211732 1.0502847103447448 1.258280832904249 1.1986606714015968 1.2887387184247403 1.0 13.349233174950667 -5.799495811206202 1.0935378846491182 1.1747573166254244 1.84490112456237 0.8822114497541662 0.09347948518708746 0.17761230659891183 0.41385497491683243 0.03431640849083946 0.09183687006757947 1.5867342230152842e-06 5.799495811206202 0.6701438079369457 YT(ph)QSNSVCYAK ddPTM_PC-9_Lapatinib_30min_R1 1 YTQSNSVCYAK 11 0 P31939-2;P31939;H7C1S2 P31939-2 ATIC Bifunctional purine biosynthesis protein PURH;Phosphoribosylaminoimidazolecarboxamide formyltransferase;IMP cyclohydrolase 1 Y(0.005)T(0.969)QS(0.025)NS(0.001)VCYAK 78.705 0.03349 0.0 4597.3 7032.1 4697.5 4547.6 5848.8 5542.8 6089.2 7197.5 4155.8 5211.5 True False 4531.7416589584345 7015.8176045009395 4311.2896828743815 4882.045674348885 5504.785083183225 5305.747364897882 6404.468981315576 7531.922125765569 3687.730041485919 6112.3008311127505 0.7414133865746635 1.1478194215816604 0.7053464484158098 0.7987247043696479 0.9006076819980526 0.8680442130548678 1.0478000278905832 1.2322564503740852 0.6033292770399464 1.0 12.577499835377697 -7.239823464118384 21.158624818795637 0.9902010959376721 0.8653801625602333 0.07562961413679659 0.18387924709963444 280.354510190677 274422.7159121066 0.06816725240005737 0.05269924682190849 5.7567389482553264e-08 7.239823464118384 -0.12482093337743883 YTCGEAPDYDR ddPTM_PC-9_AZD4547_30min_R2 1 YTCGEAPDYDR 11 0 A0A0A0MTN3;P21266 A0A0A0MTN3 GSTM3 Glutathione S-transferase Mu 3 0 103.26 0.013733 5156900.0 10405.0 10150.0 12495.0 22770.0 18692.0 20844.0 14050.0 18723.0 12645.0 12020.0 False True 13713.573562555215 13430.789005931876 12329.308135912033 17520.728292993135 16096.93844740592 19540.621384918428 15300.422781543462 15829.790561738324 13313.388884720856 11599.183458603258 1.1822878404758472 1.15790814533329 1.0629462134049819 1.5105139388064246 1.387764794380127 1.684654911671813 1.3190948169886 1.364733183006703 1.147786732767482 1.0 13.501735627860313 -5.752227746699575 24.999799057461537 1.374995540200863 1.1367334475168673 0.21441886442087787 0.17828661009800117 264.02311842547607 716535.1768571297 0.04797385481417059 0.0816342352825713 1.769180945632966e-06 5.752227746699575 -0.23826209268399556 YTCGEAPDYDR ddPTM_PC-9_Lapatinib_30min_R1 1 YTCGEAPDYDR 11 0 A0A0A0MTN3;P21266 A0A0A0MTN3 GSTM3 Glutathione S-transferase Mu 3 0 110.53 0.0088672 5338000.0 12052.0 15162.0 21787.0 15082.0 14219.0 21011.0 15083.0 16722.0 18815.0 14791.0 False True 11880.136269933877 15126.89332055051 19995.75696025208 16191.180592077104 13382.666375629587 20112.408509033212 15863.923938314203 17498.965166662292 16695.856569266474 17347.604642231352 0.6848286270608588 0.871987437604227 1.1526523328514195 0.9333381135895255 0.7714417437811881 1.159376693429545 0.9144734541444848 1.0087251541381377 0.9624300826306447 1.0 14.082448848730538 -4.89144853951129 3.8036243816398363 0.983632367325636 0.6843985151751631 0.4296307567058171 0.10698365955222108 0.2206354540233513 5.469343627394664 0.026568197760102098 0.14926186266679606 1.2839599006336905e-05 4.89144853951129 -0.2992338521504728 YTCSFCGK ddPTM_PC-9_Lapatinib_30min_R1 1 YTCSFCGK 8 0 G5E9R3;M0R0A1;C9J4Z3;Q6P4E4;E9PEL3;M0R2L6;P61513;A6NKH3 G5E9R3 RPL37A;RPL37AP8 60S ribosomal protein L37a;Putative 60S ribosomal protein L37a-like protein 0 94.302 0.029219 0.0 22034.0 24833.0 20278.0 14279.0 26503.0 26603.0 20576.0 17577.0 24301.0 24287.0 False True 21719.791119459285 24775.50071423496 18610.821115343617 15329.125293347643 24944.145646902798 25465.251704621915 21641.324600858778 18393.691587993257 21563.965479125407 28484.97558960671 0.7624999028394522 0.8697743354666864 0.6533556982275994 0.5381477419605291 0.8756948226420158 0.8939888898452628 0.7597452394782823 0.6457330998979177 0.7570294526421653 1.0 14.797913549431232 YTGEDFDEDLR ddPTM_PC-9_Lapatinib_30min_R1 1 YTGEDFDEDLR 11 0 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 180.09 0.0084777 6439500.0 18487.0 23561.0 22493.0 16028.0 22070.0 17898.0 20004.0 18467.0 18337.0 14673.0 False True 18223.371989899417 23506.445952083526 20643.712365490886 17206.75258784061 20771.885991289455 17132.5442622758 21039.709239676286 19325.044237097976 16271.69396282962 17209.20849945647 1.0589314430396366 1.3659225497108685 1.1995736100322623 0.999857290844263 1.2070215775435291 0.9955451619298418 1.2225843646638832 1.1229478821009307 0.9455225069382791 1.0 14.070893124796939 -6.93846736087328 0.25593308996705305 0.974063442474028 1.2581033992882176 0.21754920496353047 0.11284187294615423 4.701054159623254 0.7523345714404123 0.21715659109936897 0.4566158083966806 1.1522126503839046e-07 6.93846736087328 0.2840399568141896 YTGEEDGAGGHS(ph)PAPPQTEECLR ddPTM_PC-9_Lapatinib_30min_R1 2 YTGEEDGAGGHSPAPPQTEECLR 23 0 J3KS37;O94762-4;O94762;J3KSV9 J3KS37 RECQL5 ATP-dependent DNA helicase Q5 1 Y(0.001)T(0.001)GEEDGAGGHS(0.998)PAPPQTEECLR;Y(0.007)T(0.034)GEEDGAGGHS(0.959)PAPPQTEECLR 69.71 0.00063178 39866000.0 58838.0 60441.0 67010.0 64257.0 77964.0 76699.0 66820.0 70792.0 82787.0 59524.0 True False 57998.9593304323 60301.05257798397 61500.69646608028 68982.67413506826 73378.31080312148 73418.76256410156 70279.61264722893 74081.25475890191 73462.65627424196 69812.64408925554 0.8307801557591855 0.8637554609862508 0.880939223379816 0.9881114665543084 1.0510747982744677 1.051654231434575 1.006688882280069 1.0611438046120836 1.0522829672561875 1.0 16.091200732787513 -5.797150205013184 2.1793404806625047 1.0396766797133645 0.8478533536188722 0.9390585528780985 0.020468395424246725 0.06502147815626973 0.6305000844703971 0.006152011585410056 0.0113721683986452 1.5953272921930912e-06 5.797150205013184 -0.19182332609449237 YTIS(ph)QEAYDQR ddPTM_PC-9_AZD4547_30min_R2 1 YTISQEAYDQR 11 0 K7EK42;A0A494C0X0;Q99426;K7EP07;Q99426-2 K7EK42 TBCB Tubulin-folding cofactor B 1 YTIS(1)QEAYDQR 100.19 0.0042516 1738600.0 7062.8 7789.5 8626.4 10805.0 11387.0 11641.0 8357.5 8829.8 8606.5 10449.0 True False 9308.62348463383 10307.303543025244 8512.008299610372 8314.0741855859 9806.11160392742 10913.086429756055 9101.301309377197 7465.357298618648 9061.42201948202 10083.18369042807 0.9231829718098336 1.0222270921048409 0.8441786404913748 0.8245485196782064 0.9725213687455012 1.0823056253666992 0.9026217897842156 0.740377000738912 0.8986667601904341 1.0 13.299663610569644 -7.524959599762047 24.99053692134173 0.8560130086199903 0.9439706563996363 0.0765295306381818 0.09308666933617654 137.21648332430334 1647857.740002206 0.044753478831953575 0.026063162447098914 2.985660347010911e-08 7.524959599762047 0.08795764777964599 YTPASPS(ph)SPDFTTWSCAK ddPTM_PC-9_AZD4547_30min_R2 1 YTPASPSSPDFTTWSCAK 18 0 A0A1B0GVE3;O75808-2;O75808 A0A1B0GVE3 CAPN15 Calpain-15 1 YTPASPS(0.939)S(0.06)PDFTTWSCAK 195.23 1.7541e-14 13552000.0 56444.0 55729.0 75634.0 79068.0 75296.0 68246.0 69301.0 78465.0 61729.0 65728.0 True False 74392.01789186623 73742.30941000753 74631.04374162237 60840.0941884226 64842.45010356716 63978.566831469056 75468.6547461738 66340.03719632527 64991.86891774885 63426.882726046155 1.172878355273753 1.162634930814996 1.1766468811650308 0.9592162120153936 1.0223180978897406 1.0086979539544099 1.1898528116561955 1.045929333826189 1.0246738626342744 1.0 15.95280681857996 -5.737346024237828 24.999989754390604 1.0424526241910703 1.1699116421025713 0.5388931307641922 0.05695385697792131 199.86207494206445 207381.311462814 0.01633512133846196 0.028275068769039884 1.8308551068259542e-06 5.737346024237828 0.12745901791150094 YTPASPS(ph)SPDFTTWSCAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 YTPASPSSPDFTTWSCAK 18 0 A0A1B0GVE3;O75808-2;O75808 A0A1B0GVE3 CAPN15 Calpain-15 1 YTPAS(0.013)PS(0.952)S(0.035)PDFTTWSCAK;YTPASPS(0.977)S(0.023)PDFTTWSCAK;YTPAS(0.019)PS(0.976)S(0.004)PDFT(0.001)TWSCAK;YTPAS(0.002)PS(0.917)S(0.081)PDFTTWSCAK;YT(0.026)PAS(0.426)PS(0.482)S(0.067)PDFTTWSCAK 222.42 7.063699999999999e-82 11598800.0 72664.0 72381.9 83278.5 89365.0 112404.0 117189.0 127017.0 122518.0 107147.0 95135.0 True False 84964.58002058101 79567.49667668791 85264.17527546982 84358.1687752389 90379.24309886571 111043.40254055605 114985.03023655446 119302.03231855141 108713.82217279123 112382.22241175428 0.7560322104085245 0.7080078589757964 0.7586980702612611 0.7506362391211772 0.8042129899133652 0.9880869069638705 1.0231603163644853 1.061573883825182 0.9673578243939465 1.0 16.77805431011241 -6.711052814993363 2.6217880601105152 1.0188867008210534 0.7428078561513044 0.9605970396553107 0.025827262622302356 0.0478789623770557 0.6727021185195676 0.009520555838369374 0.009093144573100823 1.945123518790479e-07 6.711052814993363 -0.27607884466974897 YTPASPS(ph)SPDFTTWSCAK ddPTM_PC-9_Lapatinib_30min_R1 2 YTPASPSSPDFTTWSCAK 18 0 A0A1B0GVE3;O75808-2;O75808 A0A1B0GVE3 CAPN15 Calpain-15 1 YTPAS(0.14)PS(0.428)S(0.428)PDFT(0.002)T(0.001)WSCAK;YTPAS(0.002)PS(0.69)S(0.308)PDFTTWSCAK 185.99 2.0681999999999998e-42 8294700.0 34883.0 33144.0 39010.0 33954.0 36634.0 41868.0 37851.0 32952.0 52582.0 35224.0 True False 34385.56202324126 33067.257104361306 35802.74838295468 36451.090427223586 34479.260145215136 40077.4032390749 39810.73957363461 34483.07021719026 46659.66144699279 41312.42146697028 0.8323298611467954 0.8004192426919088 0.8666339834758745 0.8823276180111258 0.8345978986678781 0.9701054021032683 0.9636505961158369 0.8346901244885837 1.1294341941272479 1.0 15.334288003674887 -7.030635238984364 0.46856405354315794 1.0254960730709564 0.8084474602341383 0.5107115142835975 0.06809409548896896 0.9129201486785185 0.4343998378218933 0.06430103391316801 0.073761120342064 9.318902352160541e-08 7.030635238984364 -0.2170486128368181 YTPASPSS(ph)PDFTTWSCAK ddPTM_PC-9_AZD4547_30min_R2 1 YTPASPSSPDFTTWSCAK 18 0 A0A1B0GVE3;O75808-2;O75808 A0A1B0GVE3 CAPN15 Calpain-15 1 YTPASPS(0.142)S(0.857)PDFT(0.001)TWSCAK 163.91 1.6474e-07 10495000.0 65105.0 53933.0 75689.0 106290.0 93721.0 75076.0 62356.0 83302.0 65141.0 72023.0 True False 85807.03573187478 71365.78753270191 74685.31440568592 81786.48266412997 80709.45689221764 70381.48585176235 67905.56320042165 70429.58998952764 68584.2202720127 69501.49669209516 1.2346070202202446 1.026823750988643 1.0745856990181961 1.1767585815663746 1.1612621415877686 1.012661441861687 0.9770374226796323 1.0133535728236776 0.9868020623477194 1.0 16.08475642568795 -6.82879831685703 6.248184691924875 0.9960126647233151 1.1276214633570127 0.6177157729603231 0.05373693605545072 0.15302123664753256 10.746532002789928 0.019441045825035943 0.01723686731253765 1.483206715456887e-07 6.82879831685703 0.13160879863369768 YTPPTQPPIS(ph)PPYQEACTLK ddPTM_PC-9_AZD4547_30min_R2 2 YTPPTQPPISPPYQEACTLK 20 0 B7Z4K4;Q9UET6-2;Q9UET6 B7Z4K4 FTSJ1 Putative tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase 1 Y(0.001)T(0.001)PPT(0.007)QPPIS(0.983)PPY(0.007)QEACT(0.001)LK;YTPPTQPPIS(1)PPYQEACTLK 107.07 6.767100000000001e-05 7011500.0 16715.1 15055.4 22238.0 26912.0 26021.0 24083.0 18257.0 24672.0 23003.0 23344.0 True False 22030.15410432165 19921.763625606563 21943.10958994893 20707.854186255216 22408.4333051546 22577.086202887665 19881.837631504568 20859.50930615863 24218.89161844476 22526.733665360607 0.9779559891631094 0.8843609518161211 0.9740919352054525 0.9192568480577242 0.9947484459148235 1.0022352347337637 0.8825885690687993 0.9259890766247363 1.0751177679916457 1.0 14.459350520179656 -8.25428186908762 24.97935149762504 1.0375588858795817 0.9446987697037684 0.41694785394271017 0.043706328426978955 467.12209029418267 1630247.7948733 0.030751246357575344 0.011079790670717363 5.5682423735338585e-09 8.25428186908762 -0.09286011617581325 YTPPTQPPIS(ph)PPYQEACTLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YTPPTQPPISPPYQEACTLK 20 0 B7Z4K4;Q9UET6-2;Q9UET6 B7Z4K4 FTSJ1 Putative tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase 1 YTPPTQPPIS(0.999)PPYQEACTLK;YTPPT(0.002)QPPIS(0.942)PPY(0.055)QEACTLK 92.147 0.00036177 6693500.0 45585.0 55358.0 51352.0 54009.0 70031.0 60503.0 64382.0 50160.0 61894.0 46934.0 True False 53301.64015521007 60853.57639172337 52576.42643354447 50983.0508295405 56308.92827173991 57330.11617055572 58283.27087468497 48843.353148913106 62799.082658056 55442.76267066044 0.9613813884389383 1.0975927868747106 0.9483009846723818 0.9195618755939095 1.01562269914695 1.0340414764521473 1.051233164928985 0.880968963236032 1.1326831426329413 1.0 15.758711527211405 YTPPTQPPIS(ph)PPYQEACTLKR ddPTM_PC-9_AZD4547_30min_R2 2 YTPPTQPPISPPYQEACTLKR 21 1 B7Z4K4;Q9UET6-2;Q9UET6 B7Z4K4 FTSJ1 Putative tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase 1 YTPPTQPPIS(1)PPYQEACTLKR;YTPPTQPPIS(1)PPYQEACTLKR 143.09 8.5461e-05 31827000.0 32164.0 25897.0 35784.0 56813.0 46547.0 38278.0 31446.0 32171.0 30185.0 45645.0 True False 42391.48294723943 34267.69880656332 35309.480779149766 43715.64060210012 40084.75250970487 35884.47060889981 34244.633081026055 27199.711166035562 31780.517476101173 44046.98244325673 0.9624151439170664 0.7779806221846974 0.801632230417532 0.9924775359677938 0.9100453716970015 0.8146862422443527 0.7774569603069065 0.6175158809363486 0.7215140677807439 1.0 15.42675556638488 -7.0791318682103705 2.820839873252562 0.7469129188568865 0.8827810128702431 0.16044901352418828 0.10922128307146718 0.40821265503107457 6.348809136911229 0.04521101770557339 0.03459980993884947 8.334280859464147e-08 7.0791318682103705 0.13586809401335664 YTPPTQPPIS(ph)PPYQEACTLKR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YTPPTQPPISPPYQEACTLKR 21 1 B7Z4K4;Q9UET6-2;Q9UET6 B7Z4K4 FTSJ1 Putative tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase 1 YTPPTQPPIS(0.991)PPY(0.008)QEACTLKR;YTPPTQPPIS(0.996)PPY(0.003)QEACTLKR 101.28 7.9982e-05 7344200.0 28842.0 16574.4 23577.9 33105.0 37210.0 38257.0 35458.0 43956.0 40145.0 32534.0 True False 33724.380944533696 18219.796895606418 24140.08655568368 31250.23417785809 29918.967614220004 36250.73557240057 32099.16154631075 42802.20157523175 40732.044678121616 38432.15666099769 0.8775042535866427 0.4740768793258098 0.6281220897546428 0.8131272583401996 0.7784878657247677 0.9432396909744359 0.8352162442886302 1.1137080323849986 1.0598428039678016 1.0 15.230026316575321 -6.786226063426359 0.7894701824804594 1.0547968876029206 0.6456443582822569 0.6164354956366567 0.11465255245910298 0.40702021872423966 0.5532208210037853 0.07810775363426944 0.07341617904180903 1.6359647305834874e-07 6.786226063426359 -0.4091525293206637 YTPPTQPPIS(ph)PPYQEACTLKR ddPTM_PC-9_Lapatinib_30min_R1 2 YTPPTQPPISPPYQEACTLKR 21 1 B7Z4K4;Q9UET6-2;Q9UET6 B7Z4K4 FTSJ1 Putative tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase 1 YTPPTQPPIS(1)PPYQEACTLKR;YTPPTQPPIS(0.999)PPY(0.001)QEACTLKR 119.18 1.0731e-06 15778300.0 55763.0 34968.0 44774.0 35594.0 41710.0 39158.0 40664.0 34640.0 56019.0 36784.0 True False 54967.80939431819 34887.033744427514 41092.854552638084 38211.701498103204 39256.69980501512 37483.303621756364 42769.38294951988 36249.50085953726 49709.550313778316 43142.065388400915 1.274111679620622 0.8086546953731883 0.9525008638943425 0.8857179449822243 0.9099402045681753 0.8688342406488968 0.9913615067909746 0.8402356385395313 1.1522292654802548 1.0 15.396807625456173 -10.081336557896968 7.637055312937594 1.0000022568365343 0.9502353886613526 0.0 0.13854647419906896 0.0 0.0 0.12427971057244043 0.030142257283021404 8.292079211296315e-11 10.081336557896968 -0.04976686817518172 YTPSGQAGAAASESLFVS(ph)NHAY ddPTM_PC-9_AZD4547_30min_R2 2 YTPSGQAGAAASESLFVSNHAY 22 0 P04075;J3KPS3;P04075-2;H3BR68 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 YTPSGQAGAAASESLFVS(1)NHAY;YTPSGQAGAAASESLFVS(1)NHAY 166.01 6.876299999999999e-32 0.0 8822.6 11680.599999999999 14549.0 20781.8 17757.7 14443.9 14293.8 17785.1 11613.5 12925.099999999999 True False 11628.003278519915 15456.125523417515 14356.070753852273 15990.877085609342 15292.349875214015 13540.720649665282 15565.92050924028 15036.821455940413 12227.365900569841 12472.596183094258 0.9322841137341453 1.2392067614894182 1.1510090235512422 1.2820808796234315 1.2260759228252525 1.0856377013166507 1.2480096589945573 1.205588735112084 0.9803384733278858 1.0 13.606474174358851 -8.264740356907296 24.862786571769973 0.990169203673507 1.178056613132719 0.36051523598678215 0.09611864017472867 283.503579859687 2135274.818593973 0.07808832450509691 0.02341979266247018 5.435752109790835e-09 8.264740356907296 0.187887409459212 YTPSGQAGAAASESLFVS(ph)NHAY ddPTM_PC-9_Lapatinib_30min_R1 1 YTPSGQAGAAASESLFVSNHAY 22 0 P04075;J3KPS3;P04075-2;H3BR68 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 YTPSGQAGAAASESLFVS(1)NHAY 119.38 0.00014146 0.0 7058.1 5360.0 9698.7 4627.6 4944.2 8534.8 4771.3 5775.4 7567.6 6107.0 True False 6957.450199702985 5347.5892493174215 8901.31032406466 4967.929141221059 4653.3918766712 8169.786499590539 5018.334567849802 6043.746168134275 6715.257197639168 7162.586812934009 0.9713599822817374 0.7466002701232028 1.2427507765757073 0.693594265726749 0.64968034569134 1.140619543324453 0.7006315872901989 0.843793775346728 0.9375463604172916 1.0 12.806265004581245 YTPTSPSYSPS(ph)SPEYTPTSPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YTPTSPSYSPSSPEYTPTSPK 21 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YT(0.001)PT(0.002)S(0.004)PS(0.021)Y(0.012)S(0.101)PS(0.399)S(0.315)PEY(0.137)T(0.007)PT(0.002)SPK 90.581 0.00023819999999999996 3233100.0 17539.0 16262.0 19767.0 16137.0 21780.0 21560.0 21431.0 18982.0 16230.0 15735.0 True False 20508.006288959725 17876.383888186083 20238.320246764968 15232.896206859883 17512.3653490382 20429.355645789157 19400.90053299639 18483.742613091472 16467.333045856616 18587.63094180853 1.10331469099872 0.961735465060119 1.088805792955766 0.8195178963122753 0.9421515524954946 1.099083347939629 1.0437532676290986 0.9944108892067904 0.8859296323135619 1.0 14.182055285024584 -2.9644004989387667 1.806542426698811 0.9829762605281708 79.412292654524 0.15719505068218076 0.08228881868303298 1878.1570986026402 12.105363889686977 0.02305909067581083 608508.49906025 0.001085424202317637 2.9644004989387667 78.42931639399582 YTPTSPSYSPSS(ph)PEYTPTSPK ddPTM_PC-9_AZD4547_30min_R2 1 YTPTSPSYSPSSPEYTPTSPK 21 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 YTPTS(0.001)PS(0.004)Y(0.001)S(0.027)PS(0.186)S(0.78)PEYTPTSPK 119.76 8.0621e-05 0.0 30872.0 21966.0 27530.0 45935.0 34123.0 31143.0 26304.0 30004.0 29501.0 29997.0 True False 40688.65382250888 29066.079931458073 27164.93421221756 35345.39543867545 29385.610455854512 29195.623286821825 28645.005042399967 25367.571223329414 31060.362632514825 28946.81416037619 1.405634955096561 1.0041201691633872 0.9384429686014375 1.2210461311164926 1.0151587077267719 1.0085953889456414 0.9895736671986047 0.8763510582817013 1.0730148907036465 1.0 14.821116955814325 -4.760619011927325 24.99300720646755 1.0133773785484756 1.4056354126374353 0.6573773012292625 0.08481252080850962 12.587295559794082 383249.0032213174 0.02151920492547652 0.12597644763601656 1.7353256575858407e-05 4.760619011927325 0.39225803408895965 YTQVGPDHNR ddPTM_PC-9_AZD4547_30min_R2 1 YTQVGPDHNR 10 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 0 106.16 0.001978 3811800.0 11306.0 12729.0 21758.0 25523.0 20830.0 19075.0 13757.0 25499.0 17400.0 20133.0 False True 14901.072820590995 16843.400320838093 21469.474703575353 19639.06667641915 17938.11405197227 17882.237234567212 14981.34634915969 21558.71545872806 18319.728477195953 19428.14979800828 0.7669836281640474 0.8669585367601413 1.1050704738634631 1.0108562513982928 0.9233053192646906 0.9204292441887827 0.7711154435660948 1.1096638477091731 0.9429476644798179 1.0 14.245860894763197 -5.013337189676115 8.4111161785618 0.9686434660905733 0.7908936054931687 0.33456579958944765 0.09268158506544356 0.1721370873558104 93.42675259321949 0.024157510264377062 0.07418521890148072 9.697567480593079e-06 5.013337189676115 -0.1777498605974046 YTQVGPDHNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 YTQVGPDHNR 10 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 0 ;; 112.83 0.0011700999999999999 7725000.0 49596.0 52604.0 59366.0 67653.0 68437.0 59119.0 62035.0 60195.0 60350.0 43961.0 False True 57991.62323434899 57826.177472275296 60781.51058680876 63862.62174398533 55027.26112911513 56018.69556694848 56158.59570549348 58614.94503187451 61232.50457901704 51930.7813049155 1.1167100085370716 1.1135241184365112 1.1704332008780214 1.2297643158690628 1.0596270602211513 1.0787185202939753 1.081412493599009 1.1287129436338044 1.1791177224830447 1.0 15.66430231066065 -6.288652161169276 24.987662756576185 1.0935805106862806 1.1553751895289663 0.291266879655523 0.05276077261844021 1109.8487213239332 1019096.1313898002 0.01694579284768638 0.019218795804728333 5.14455528716558e-07 6.288652161169276 0.061794678842685746 YTQVGPDHNR ddPTM_PC-9_Lapatinib_30min_R1 3 YTQVGPDHNR 10 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 0 ;; 131.42 0.00015145 8664700.0 71017.0 69906.0 79730.0 76042.0 77340.0 87108.0 65881.0 62962.0 79872.0 61053.0 False True 70004.28455707736 69744.1369520118 73174.90716670024 81634.38234867588 72791.0132562903 83382.59389866583 69291.99582179131 65887.4443740816 70875.97427055286 71605.92970199112 0.977632506810826 0.9739994612495403 1.0219112784547157 1.1400505892238406 1.0165500756603714 1.1644649297297964 0.967685163926648 0.9201395002940588 0.989805935982171 1.0 16.12779144186351 -7.477432605825418 24.999774647744577 0.9617659098574975 1.0486870177502692 0.28301754985177385 0.06173278842379825 545.9536579384855 300328.00339062134 0.0268149487020525 0.018077777285886505 3.33094448168502e-08 7.477432605825418 0.08692110789277163 YTVQDESHSEWVSCVR ddPTM_PC-9_AZD4547_30min_R2 1 YTVQDESHSEWVSCVR 16 0 D6R9L0;P63244;D6R9Z1;D6RFX4;D6RHH4;H0Y8W2;J3KPE3;H0YAM7;H0YAF8;D6RFZ9;D6RBD0 D6R9L0 GNB2L1 Guanine nucleotide-binding protein subunit beta-2-like 1;Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed 0 109.1 0.00060489 6868500.0 37653.0 18283.0 44998.0 46166.0 42375.0 40451.0 52408.0 68653.0 51465.0 42352.0 False True 49625.87076894682 24192.622206448494 44401.29711882911 35523.141957589876 36491.96269574289 37921.59257538549 57072.210472251245 58044.25633899601 54185.33483212012 40869.26937094554 1.214258819224854 0.5919514241095615 1.0864225811287571 0.869189552550301 0.8928949124225223 0.927875471205375 1.3964578117176856 1.420242084882006 1.3258209815378086 1.0 15.318728831757165 -7.253558549716384 23.894028887286655 1.3206503954707034 0.9176470890716529 0.4631807580789544 0.1855034957938741 244.58390059564735 741560.0169138393 0.0669124382418009 0.050801502883793155 5.577524032893332e-08 7.253558549716384 -0.40300330639905046 YVAQAHDKPR ddPTM_PC-9_AZD4547_30min_R2 1 YVAQAHDKPR 10 1 I3L239;I3L0K7;Q12931-2;Q12931 I3L239 TRAP1 Heat shock protein 75 kDa, mitochondrial 0 95.523 0.0026511 6337400.0 23617.0 20008.0 28857.0 32561.0 28948.0 27226.0 26230.0 32102.0 25860.0 24060.0 False True 31126.7147358834 26475.194722234966 28474.337325171142 25054.564512435223 24929.069878852286 25523.553916032844 28564.41918575695 27141.37353057327 27226.906805763654 23217.66672329405 1.3406478397182902 1.1403038486926282 1.2264082202800821 1.0791163819789968 1.0737112465242342 1.0993160604904937 1.23028810457937 1.1689966030627275 1.1726805768319164 1.0 14.502935374325205 -1.5228787452844437 0.015995308051227966 1.1159534607640822e-10 2.559020911375453 0.3282383653306703 0.07574842580593572 7294.925077980977 9.03978483547682 569.8265958470221 913.8694026363064 0.02999999999971636 1.5228787452844437 2.559020911263858 YVASVLGLTPS(ph)PR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YVASVLGLTPSPR 13 0 Q99666;O14715;F8W705;Q99666-2;C9J1W9;C9JF75 Q99666 RGPD5;RGPD8;RGPD6 RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8 1 YVASVLGLT(0.047)PS(0.953)PR 88.075 0.0067828 5401100.0 23054.0 20998.0 18705.0 24077.0 28306.0 21660.0 24044.0 17889.0 19121.0 17653.0 True False 26956.586862744618 23082.542669052484 19150.998139107527 22728.043748687192 22759.6424963212 20524.11146974923 21766.37825651462 17419.432704962255 19400.608451621953 20853.3491589289 1.2926742202080503 1.1068985846414554 0.918365582101594 1.0898989690083232 1.0914142530710023 0.9842117596233362 1.0437833314268745 0.8353302182879183 0.9303353770065793 1.0 14.347991486334472 -1.5228787676798246 0.8553481877986863 0.9807793720971475 116.73380344492045 0.5970146476413152 0.07663722356900449 519.8041530143026 1.407355334323671 0.028548501916890637 117126.09536844093 0.029999998452698295 1.5228787676798246 115.75302407282331 YVASYLLAALGGNSS(ph)PSAK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YVASYLLAALGGNSSPSAK 19 0 P05387 P05387 RPLP2 60S acidic ribosomal protein P2 1 YVASYLLAALGGNS(0.191)S(0.617)PS(0.191)AK 85.57600000000001 0.0012865 854210.0 2633.1 2014.0 2446.1 2968.9 3564.0 3104.2 4456.6 2917.9 3427.7 1980.1 True False 3078.8318239044343 2213.9366099376934 2504.42430088591 2802.5621583036673 2865.659784388071 2941.4102873682154 4034.43858501011 2841.3082167706057 3477.823627928694 2339.0764555370242 1.316259593232309 0.9465003184042566 1.0706893718490804 1.19814901803209 1.2251244620946558 1.257509253451445 1.724799792439384 1.214713700377218 1.4868362338888264 1.0 11.19172330335175 -6.553805970683764 1.7892591498273163 1.3777256174923114 1.1100736148860963 0.18830490053488902 0.19675548070364451 0.4789414214736736 3.115033859026563 0.07318372351187209 0.07797195517806198 2.7937917420288766e-07 6.553805970683764 -0.267652002606215 YVASYLLAALGGNSS(ph)PSAK ddPTM_PC-9_Lapatinib_30min_R1 2 YVASYLLAALGGNSSPSAK 19 0 P05387 P05387 RPLP2 60S acidic ribosomal protein P2 1 YVASYLLAALGGNS(0.249)S(0.749)PS(0.002)AK;YVASYLLAALGGNS(0.07)S(0.928)PS(0.001)AK 169.06 5.777e-08 60401000.0 13563.3 9623.5 12745.900000000001 11920.5 12213.099999999999 12580.4 11715.8 10109.1 12808.3 7606.099999999999 True False 13369.884854795406 9601.217377016083 11697.981302596821 12797.173335622272 11494.749469878443 12042.365618344753 12322.386798150337 10578.805691083944 11365.694376621619 8920.80425050882 1.498730885618617 1.0762726215484948 1.3113146499016162 1.4345313467552383 1.2885328662180668 1.3499192763542467 1.3813089551255986 1.1858578435324996 1.2740661107963835 1.0 13.122958066098759 -8.960029504771404 0.864239223684872 0.9996361641126503 1.3227419296132679 0.42939159823733963 0.1112064907642998 1.4222587613060325 1.7639186157161266 0.10869821392804847 0.03585929347305933 1.0964037069636791e-09 8.960029504771404 0.32310576550061754 YVDEENS(ph)DGETSNHR ddPTM_PC-9_AZD4547_30min_R2 2 YVDEENSDGETSNHR 15 0 A0A494C108;Q8N9T8;H0YFD2;F8WFC1;H0YH26 A0A494C108 KRI1 Protein KRI1 homolog 1 YVDEENS(0.999)DGETSNHR;YVDEENS(1)DGETSNHR 111.62 0.0011899 7810900.0 12381.699999999999 5869.4 38046.0 68189.0 52335.0 46415.0 30769.0 50570.0 27549.0 45440.0 True False 16318.82304464104 7766.568767627241 37541.48518118523 52469.0795595481 45069.18861785735 43512.662712578596 33507.38139254882 42755.56848299457 29005.18389760182 43849.15943085958 0.37215817261838763 0.17712012883333375 0.8561506233746587 1.1965811942707871 1.027823319827179 0.992326039480607 0.7641510539188908 0.9750601616528279 0.6614763948516863 1.0 15.42026156665381 -5.3180069339376494 5.408420427830957 0.9462065312030098 0.2744792848264362 0.7664922076708693 0.14588461902659786 0.08622744670153716 5.485285969134018 0.0394083760584858 0.08612973889959752 4.808316714388881e-06 5.3180069339376494 -0.6717272463765736 down YVDEENS(ph)DGETSNHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YVDEENSDGETSNHR 15 0 A0A494C108;Q8N9T8;H0YFD2;F8WFC1;H0YH26 A0A494C108 KRI1 Protein KRI1 homolog 1 YVDEENS(1)DGETSNHR;YVDEENS(0.998)DGET(0.001)S(0.001)NHR 106.31 0.0016464000000000001 8204700.0 24205.5 25406.0 55394.0 57087.0 68750.0 57093.0 51512.0 51097.0 48538.0 36830.0 True False 28303.01306958292 27928.139777595374 56714.80304291485 53888.60046855112 55278.93102600442 54098.94257351764 46632.410445416004 49755.75789174668 49247.77642512558 43506.98745388041 0.6505394817231493 0.6419230889567016 1.303579180310643 1.2386194407433 1.2705759295470151 1.2434541148330538 1.0718372651025012 1.1436268241852021 1.1319509648267578 1.0 15.408959503625898 -5.253939511771506 24.951687811365815 1.184965885175508 0.646231199061346 0.8494969954811082 0.08903082711014401 191.46238423289347 636981.9554785192 0.023396055063213645 0.05934744040257946 5.572633587738365e-06 5.253939511771506 -0.5387346861141621 YVDEENS(ph)DGETSNHR ddPTM_PC-9_Lapatinib_30min_R1 1 YVDEENSDGETSNHR 15 0 A0A494C108;Q8N9T8;H0YFD2;F8WFC1;H0YH26 A0A494C108 KRI1 Protein KRI1 homolog 1 YVDEENS(0.895)DGET(0.091)S(0.014)NHR 76.704 0.0077493 7841100.0 9619.5 7979.3 18390.0 10536.0 12995.0 17719.0 10704.0 13507.0 17699.0 9989.3 True False 9482.324165999747 7960.824421096734 16878.045187452863 11310.85258706567 12230.659649153 16961.199675006406 11258.200744925756 14134.584529727761 15705.552241267469 11715.937195094428 0.8093525945128901 0.6794867784397142 1.4406056388318518 0.9654244810907342 1.0439335279361255 1.4477031920338579 0.9609304452092547 1.2064407903830385 1.34052888639959 1.0 13.516184744133321 -5.243552782821384 24.972094473020125 1.17289762279559 0.744419607415961 0.48232371794265905 0.17870204739707501 662.3916509539949 924784.4389128793 0.04365910439191232 0.11495820368352518 5.707517045419966e-06 5.243552782821384 -0.42847801537962904 YVDIAIPCNNK ddPTM_PC-9_Lapatinib_30min_R1 2 YVDIAIPCNNK 11 0 C9J9K3;A0A0C4DG17;P08865 C9J9K3 RPSA 40S ribosomal protein SA 0 ; 204.79 3.2239e-05 17017200.0 120762.0 118808.0 135322.0 131133.0 154613.0 135235.0 143449.0 125879.0 123383.0 136446.0 False True 119039.9117349615 118532.90737554152 124196.34751802617 140776.95826686415 145518.9673208535 129451.31429818232 150876.08731865237 131727.7978838825 109486.30725941046 160030.50929713348 0.7438576072637281 0.7406894341344492 0.7760791867969817 0.8796882474796061 0.9093201537630805 0.8089164676582148 0.9427957705147096 0.823141777542553 0.6841589628145464 1.0 17.287987450897525 -5.630845345895337 4.282340577789171 0.859320933194372 0.7455087012972815 0.2883408389189033 0.08022688761841325 0.2857989962969391 9.261932345107528 0.021996072415982754 0.03965587231904639 2.3396702568191235e-06 5.630845345895337 -0.11381223189709044 YVDSEGHLY(ph)TVPIR ddPTM_PC-9_AZD4547_30min_R2 1 YVDSEGHLYTVPIR 14 0 Q03135 Q03135 CAV1 Caveolin-1 1 YVDSEGHLY(0.738)T(0.262)VPIR 138.55 0.00015432 5944600.0 10138.0 19670.0 30071.0 30345.0 30317.0 28936.0 22905.0 33297.0 22099.0 23173.0 True False 13361.673116500222 26027.942832185196 29672.238891957633 23349.4290755765 26108.00785951237 27126.627345710967 24943.500627135447 28151.71373894145 23267.108023997334 22361.72032331226 0.5975243819935704 1.1639508256013233 1.3269211162177046 1.0441696228189807 1.167531275860497 1.2130832044004798 1.1154553525621043 1.2589243283573794 1.0404882847828663 1.0 14.448743560862955 -4.761189865452859 24.9123850640375 1.159926817459505 0.5975237302711927 0.7389813540062852 0.09788095795506921 2.6283435546297342 261888.35217395928 0.022729125068039025 0.1284468792294407 1.7330461766266587e-05 4.761189865452859 -0.5624030871883123 YVDSEGHLY(ph)TVPIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 2 YVDSEGHLYTVPIR 14 0 Q03135 Q03135 CAV1 Caveolin-1 1 YVDSEGHLY(0.924)T(0.076)VPIR;YVDSEGHLY(0.858)T(0.142)VPIR 77.633 0.025917000000000003 14781000.0 48356.0 43637.0 63949.0 55545.0 92079.0 58095.0 70641.0 56860.0 57790.0 50364.0 True False 56541.71572546534 47968.992973113774 65473.78668793307 52432.99372931967 74036.78094463205 55048.39592959744 63949.373083449085 55367.48524814994 58635.06942206125 59494.594518795384 0.9503672759313088 0.8062748113689476 1.1004997549356985 0.8813068507048177 1.2444287005140027 0.9252671839322594 1.0748770304375528 0.9306305168725603 0.9855528875574974 1.0 15.860470975445864 -5.2586427946653425 24.996656291470995 1.017292823181565 0.8783210464459009 0.2237866377067591 0.10391780238979553 336.5836201134645 3008434.453360946 0.02507086752790014 0.0605414706894685 5.512609197170601e-06 5.2586427946653425 -0.13897177673566408 YVDSEGHLY(ph)TVPIR ddPTM_PC-9_Lapatinib_30min_R1 2 YVDSEGHLYTVPIR 14 0 Q03135 Q03135 CAV1 Caveolin-1 1 YVDSEGHLY(0.686)T(0.314)VPIR;YVDSEGHLY(0.718)T(0.282)VPIR 121.76 0.00011752 12941700.0 74736.0 76772.0 53532.0 30502.0 54551.0 42488.0 39276.0 28035.0 63559.0 26220.0 True False 73670.25093509599 76594.2391508578 49130.80559949577 32745.21883168918 51342.41743139243 40670.88728436551 41309.51910105604 29337.608446799255 56400.31611405836 30752.092064046115 2.3956175333263827 2.4907001120879233 1.5976410807164945 1.0648127211472982 1.6695585238384332 1.3225405022741845 1.3433076037565965 0.954003662115053 1.8340318439667698 1.0 14.90839693984711 -5.3509637746148275 3.670543307391318 1.3273282359362921 2.454496124603969 0.7364054182394852 0.26587918359520907 0.1055342645093403 2.635268017213316 0.06714730115308817 0.1584505504685041 4.456934230410896e-06 5.3509637746148275 1.127167888667677 YVEVS(ph)PATER ddPTM_PC-9_AZD4547_30min_R2 1 YVEVSPATER 10 0 Q9NTZ6 Q9NTZ6 RBM12 RNA-binding protein 12 1 YVEVS(0.984)PAT(0.016)ER 78.548 0.020245 3641600.0 17054.0 15176.0 24940.0 29908.0 25647.0 27353.0 19430.0 27648.0 19945.0 22102.0 True False 22476.817254763744 20081.345217145037 24609.279304493488 23013.1726739938 22086.35674944468 25642.612585956307 21159.232359102458 23375.63688783534 20999.251981475474 21328.215707325235 1.0538536164112415 0.9415389216195916 1.1538367598205304 1.079001309335495 1.0355463885269625 1.2022858797864315 0.9920770049149147 1.0959958961689849 0.9845761253372556 1.0 14.380475656157742 -8.27072636417179 24.20466072403998 0.992288038925766 1.0688897865677147 0.16094414401502688 0.0703013192653162 893.42785019466 2328499.3744196636 0.06310265026927124 0.01718836862273802 5.361343531696435e-09 8.27072636417179 0.07660174764194871 YVEVS(ph)PATER ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YVEVSPATER 10 0 Q9NTZ6 Q9NTZ6 RBM12 RNA-binding protein 12 1 YVEVS(0.992)PAT(0.008)ER 83.081 0.014033000000000002 3274600.0 19598.0 22150.0 26119.0 25314.0 34212.0 22428.0 26052.0 20938.0 19666.0 22440.0 True False 22915.554321856016 24348.90561574972 26741.776016859105 23895.738649095303 27508.404192896913 21251.836197762495 23584.16595985357 20388.39968564479 19953.57804558327 26508.194365057738 0.8644705861996611 0.9185425940533195 1.0088116771962887 0.9014472400501903 1.0377320995185406 0.8017081776711277 0.8896934146122555 0.7691357398722009 0.7527324483438013 1.0 14.694150782334953 -6.78277482609425 24.995830947244375 0.8311648833360399 0.9456563671474889 0.28827664050423896 0.08033999297750438 282.0426370503437 330428.57146935846 0.027394258944393454 0.024181703467747697 1.649017155759141e-07 6.78277482609425 0.11449148381144902 YVEVS(ph)PATER ddPTM_PC-9_Lapatinib_30min_R1 2 YVEVSPATER 10 0 Q9NTZ6 Q9NTZ6 RBM12 RNA-binding protein 12 1 YVEVS(0.996)PAT(0.004)ER;YVEVS(0.947)PAT(0.053)ER 130.01 0.00022743 6598200.0 35274.0 37039.0 49960.0 32045.0 38354.0 38455.0 32786.0 34778.0 49502.0 28475.0 True False 34770.98629154063 36953.23847116938 45852.481651177 34401.69619898628 36098.093126865235 36810.369292983305 34483.498656869946 36393.91284333099 43926.563480830686 33396.86580944748 1.0411451927834625 1.1064882160503773 1.3729576276048636 1.030087565559956 1.0808826592540195 1.1022102943136116 1.0325369707930818 1.0897403681825641 1.3152899955182173 1.0 15.02742509622083 YVGFGNT(ph)PPPQK ddPTM_PC-9_AZD4547_30min_R2 3 YVGFGNTPPPQK 12 0 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHT6;E5RHC5;F8W1U7;Q8N6T3-3 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 YVGFGNT(1)PPPQK;Y(0.001)VGFGNT(0.999)PPPQK;YVGFGNT(1)PPPQK 130.1 0.00038127 19308500.0 137913.0 143640.0 153888.0 160410.0 153411.0 160152.0 131817.0 175720.0 154132.0 137237.0 True False 181766.46523139626 190068.82096670457 151847.34457136714 123429.95280979494 132112.53071661643 150137.67012269516 143548.4576366347 148566.5116438954 162279.1028532856 132432.374401692 1.3725228899095683 1.4352141749734888 1.146602900215214 0.9320225010495465 0.9975848527482756 1.1336931079050179 1.0839378081467115 1.1218292529685043 1.2253733544115348 1.0 17.01489632074651 -5.348549627606628 4.345020220089329 1.073933956829924 1.4042184740110353 0.7289374270825777 0.079805673930436 0.11148450427148952 3.7295492632954006 0.022561503788332982 0.050612832973681625 4.481778329883772e-06 5.348549627606628 0.3302845171811113 YVGFGNT(ph)PPPQK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YVGFGNTPPPQK 12 0 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHT6;E5RHC5;F8W1U7;Q8N6T3-3 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 YVGFGNT(1)PPPQK 105.17 0.0022035 0.0 21768.0 24525.0 23669.0 21214.0 22805.0 24379.0 27553.0 22965.0 23580.0 20323.0 True False 25452.892462402386 26959.679919921542 24233.358725182377 20025.448356715966 18336.523957062273 23100.52232322327 24942.980373554645 22362.19308342881 23924.812891022753 24007.399023220514 1.0602103308977269 1.1229737921149023 1.0094120859049875 0.8341365233837654 0.7637863618348144 0.9622251165517726 1.0389705419328938 0.9314708795317468 0.9965599716938148 1.0 14.551191489091812 -5.524638841195948 7.374933067002861 0.9275849714141686 1.0858893075464708 0.39933781070786 0.07825189202364481 0.12648100451899486 47.42565761566081 0.02326721784223425 0.04299763923852796 2.9878662923223633e-06 5.524638841195948 0.15830433613230221 YVGFGNT(ph)PPPQK ddPTM_PC-9_Lapatinib_30min_R1 4 YVGFGNTPPPQK 12 0 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHT6;E5RHC5;F8W1U7;Q8N6T3-3 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 YVGFGNT(1)PPPQK;Y(0.054)VGFGNT(0.946)PPPQK;YVGFGNT(1)PPPQK;YVGFGNT(1)PPPQK 142.39 0.00019880000000000003 16527000.0 145989.0 175041.0 192392.0 159481.0 197959.0 219940.0 231702.0 225389.0 213708.0 183084.0 True False 143907.17008889618 174635.70331898704 176574.27241459687 171209.76475302002 186315.44082236863 210533.67890518118 243698.39583340674 235861.39576299794 189637.95459499356 214729.8254559042 0.6701778375843191 0.8132810751753222 0.8223090203687481 0.7973264281732431 0.867673786940368 0.9804584829246986 1.1349070643353705 1.0984100381129085 0.8831467831371967 1.0 17.712163066420047 -6.662912546529484 2.1110490435163523 1.0393817206635976 0.7811835578086233 0.7105615411487346 0.07392456497826502 0.17438582951095877 1.591987576425909 0.02889240700921972 0.028392343125911525 2.173138737706376e-07 6.662912546529484 -0.2581981628549743 YVGFGNT(ph)PPPQKK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YVGFGNTPPPQKK 13 1 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHT6;E5RHC5;F8W1U7;Q8N6T3-3 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 Y(0.001)VGFGNT(0.999)PPPQKK 68.413 0.027913999999999998 46419000.0 106570.0 93719.0 87596.0 124030.0 131950.0 155510.0 163140.0 144040.0 122560.0 103450.0 True False 124610.19614655574 103022.80295270646 89684.62084967973 117081.00121068569 106095.34471100061 147354.78184029105 147686.19816868223 140259.10262299533 124352.20813925962 122204.66609025055 1.0196844370453797 0.8430349367889283 0.7338886780595257 0.9580730831032185 0.8681775263200433 1.2058032361175688 1.2085152138103552 1.1477393385242034 1.0175733228338684 1.0 16.89893984647353 -6.752292935934097 24.983539163781 1.1309467446586619 0.8779762100278816 0.5941687639459015 0.09511983163322577 128.29435118707752 350435.9708376955 0.032142837264178145 0.03170824984436211 1.768915404851385e-07 6.752292935934097 -0.25297053463078023 YVGFGNT(ph)PPPQKK ddPTM_PC-9_Lapatinib_30min_R1 1 YVGFGNTPPPQKK 13 1 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHT6;E5RHC5;F8W1U7;Q8N6T3-3 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 YVGFGNT(1)PPPQKK 62.69 0.041122000000000006 34106000.0 268770.0 232400.0 310100.0 237150.0 299360.0 348670.0 327530.0 284300.0 337840.0 286340.0 True False 264937.29051361786 231861.89207861357 284604.77502061595 254590.80210920906 281752.233364405 333758.19688946835 344487.900783402 297509.61588817666 299788.90158708394 335833.48747593316 0.7888947957657262 0.690407302205768 0.8474579981873058 0.758086407709576 0.8389640815214897 0.9938204775168125 1.0257699533554974 0.8858843057141438 0.8926712575337434 1.0 18.357386569532082 -6.581076092704494 3.9631400258340834 0.9560198964551604 0.772734848517634 0.7242653394852608 0.05508380246298041 0.1262041159592734 4.073106887637837 0.01954447641799529 0.01988157921014588 2.62375879452234e-07 6.581076092704494 -0.18328504793752642 YVLGQLVGLNS(ph)PNSILK ddPTM_PC-9_AZD4547_30min_R2 2 YVLGQLVGLNSPNSILK 17 0 P33981-2;P33981 P33981-2 TTK Dual specificity protein kinase TTK 1 YVLGQLVGLNS(0.627)PNS(0.373)ILK;YVLGQLVGLNS(0.992)PNS(0.008)ILK 206.59 2.5087999999999998e-17 8038600.0 39866.0 38291.0 50052.0 70570.0 61414.0 51716.0 41475.0 64285.0 46733.0 51013.0 True False 52542.558735687286 50667.81692868345 49388.27777660414 54301.17679563135 52887.72618280479 48482.19034458075 45166.19465227866 54351.230372341364 49203.21097268961 49227.05039714874 1.0673513507673127 1.0292677810250879 1.003275178548271 1.1030759787057343 1.074363094195627 0.984868887195989 0.917507636307511 1.1040927687897673 0.9995157251091259 1.0 15.587163677828485 -6.763476268070997 24.999566841987203 1.0024722138994036 1.0537566172409867 0.2337609712042048 0.04905137356685614 94.68820578668246 1162134.7856746565 0.017583114460660087 0.016282162648759146 1.7239462931292879e-07 6.763476268070997 0.05128440334158313 YVLGQLVGLNS(ph)PNSILK ddPTM_PC-9_Lapatinib_30min_R1 1 YVLGQLVGLNSPNSILK 17 0 P33981-2;P33981 P33981-2 TTK Dual specificity protein kinase TTK 1 YVLGQLVGLNS(0.999)PNS(0.001)ILK 190.24 3.0961e-42 0.0 11454.0 11660.0 8760.7 10341.0 9578.4 10266.0 9720.4 6258.9 9165.6 8000.5 True False 11290.663859593651 11633.001986388264 8040.429063279959 11101.51163656474 9015.01734385895 9826.947111214844 10223.674749717524 6549.7113432378055 8133.273609953163 9383.375765003844 1.2032624657005864 1.2397459376799773 0.8568802171674157 1.1831042382389545 0.9607435074146001 1.0472720433796694 1.0895518847116463 0.6980122620331961 0.8667747955151651 1.0 13.195891325022489 -3.8792355157668696 0.3162141345130962 0.884393328819893 1.7439567370737814 0.3436789591149212 0.13347164339303288 14.819079457189904 0.7698415022286388 0.1394674493311823 5.443434842190039 0.0001320579296297303 3.8792355157668696 0.8595634082538884 YVLGQLVGLNSPNS(ph)ILK ddPTM_PC-9_Lapatinib_30min_R1 1 YVLGQLVGLNSPNSILK 17 0 P33981-2;P33981 P33981-2 TTK Dual specificity protein kinase TTK 1 YVLGQLVGLNS(0.002)PNS(0.998)ILK 190.8 9.5361e-09 6529700.0 41611.0 38350.0 36852.0 33577.0 34637.0 35374.0 31394.0 31259.0 37240.0 28792.0 True False 41017.619509477154 38261.20293121699 33822.17081283378 36046.36458958846 32599.71975896207 33861.13648082152 33019.42770797826 32711.407256589897 33045.63904541502 33768.65883707153 1.2146653412378832 1.133038866477383 1.0015846639341062 1.0674502876618968 0.96538390571715 1.00273856430592 0.9778128254157741 0.9686913363784239 0.9785890285088025 1.0 15.04339726166272 -4.043607085327626 0.6740946913560674 0.9799515589479013 1.727488434439831 0.8864060324539256 0.026508795297801264 2.1534323141443736 0.35865741401148465 0.01053505993116296 1.5489577008082618 9.044673929308344e-05 4.043607085327626 0.7475368754919296 YVPPHLS(ph)PDKK ddPTM_PC-9_Lapatinib_30min_R1 1 YVPPHLSPDKK 11 1 Q86W56;Q86W56-3;Q86W56-2;Q86W56-4 Q86W56 PARG Poly(ADP-ribose) glycohydrolase 1 YVPPHLS(1)PDKK 60.196000000000005 0.029616000000000003 5041900.0 84494.0 68764.0 60771.0 60400.0 66261.0 65060.0 52880.0 60551.0 63327.0 51397.0 True False 83289.10006569794 68604.78118284757 55774.64296284381 64842.01748849342 62363.65825413824 62277.53546226742 55617.86765617285 63364.42051229332 56194.44639712663 60280.90296780236 1.3816830200799228 1.138084829609988 0.9252456452524366 1.0756643364006553 1.0345508309231588 1.0331221397849915 0.9226448994282623 1.0511524776949335 0.9322097651248122 1.0 15.879413407258472 -4.857580107982434 2.805163769971966 1.0017011890846486 1.4194278400206435 0.8319133018330328 0.05299909229103357 0.13074710521606112 1.6010987713669051 0.013196248225619052 0.11733082206763992 1.3880972442168869e-05 4.857580107982434 0.4177266509359949 YVQHTYR ddPTM_PC-9_AZD4547_30min_R2 4 YVQHTYR 7 0 F5H3P3;P52566;H0YGX7 F5H3P3 ARHGDIB Rho GDP-dissociation inhibitor 2 0 ;;; 133.81 0.0035118000000000003 30954200.0 105460.0 111720.0 152432.0 188924.0 168143.0 151833.0 113535.0 175831.0 120945.0 134268.0 False True 138994.08629573055 147831.30519632593 150410.6520827006 145370.49064670346 144799.24680944634 142338.8585077873 123639.39505356114 148660.3591444216 127337.90578588877 129567.31818799877 1.0727557553831113 1.1409613725416976 1.160868760627265 1.121968816517254 1.1175599590580894 1.0985706928135797 0.9542483149505621 1.147360007318507 0.9827934047467496 1.0 16.98334233591475 -7.022308849093755 18.530356397906633 1.032384201828084 1.124113997041869 0.4572154899593598 0.05210816565764914 27.670893284511966 22983.473503321748 0.018793694880014627 0.014782451905665118 9.49929010123829e-08 7.022308849093755 0.09172979521378499 YVQHTYR ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 YVQHTYR 7 0 F5H3P3;P52566;H0YGX7 F5H3P3 ARHGDIB Rho GDP-dissociation inhibitor 2 0 ;;;; 130.77 0.0036650999999999997 24422600.0 91408.0 83411.0 95735.0 101013.0 118489.0 104720.0 114050.0 96615.0 96006.0 85467.0 False True 106881.56900970613 91691.49283590529 98017.68547700925 95353.56909856445 95271.93103040344 99228.2988509759 103246.35834950478 94078.95862205404 97409.90612449226 100961.49054360027 1.0586369954943293 0.9081828362697187 0.970842297882679 0.9444548469437063 0.9436462409324297 0.9828331408015822 1.0226310823424083 0.9318301276606648 0.9648223852482224 1.0 16.623445589235864 -6.7967543671502 24.71040312930364 0.978800723614164 0.9611538375963955 0.02681796605507325 0.042162227036706065 635.9309017244994 444965.76191945496 0.014480042546366928 0.012770867019725 1.5967820166858192e-07 6.7967543671502 -0.017646886017768537 YVQHTYR ddPTM_PC-9_Lapatinib_30min_R1 3 YVQHTYR 7 0 F5H3P3;P52566;H0YGX7 F5H3P3 ARHGDIB Rho GDP-dissociation inhibitor 2 0 ;; 133.81 0.00027803 18528100.0 172799.0 136534.0 129593.0 115145.0 126331.0 133916.0 122132.0 111802.0 132937.0 102715.0 False True 170334.85457254437 136217.86391162415 118938.3637834462 123613.14741245963 118900.45895630225 128188.72485344326 128455.39736353444 116996.72907326758 117964.23517133026 120469.15089086554 1.4139292367624703 1.1307281814829555 0.9872931194741623 1.0260979387531524 0.9869784760416849 1.0640792593414308 1.0662928759239263 0.9711758421810105 0.9792069944794041 1.0 16.878304230396687 -4.782982238578136 2.383850202941684 1.012884809116439 1.508770677837717 0.934354903874258 0.032413036661065334 0.13613789756127845 0.9506013710543126 0.009063113324089963 0.1419827395545328 1.6482297981064566e-05 4.782982238578136 0.49588586872127793 YVS(ph)GSSPDLVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YVSGSSPDLVTR 12 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 YVS(0.657)GS(0.216)S(0.127)PDLVTR 152.96 0.00020727 19404000.0 31119.0 34548.0 40961.0 44173.0 42557.0 30515.0 38323.0 37955.0 33061.0 24159.0 True False 36386.832071733734 37977.6971202222 41937.665585457544 41698.13002079827 34218.261347980675 28914.739681412644 34692.76800550701 36958.72146664666 33544.45457973295 28538.83545746122 1.2749935829011105 1.330737449915577 1.469494634704631 1.4611013151868701 1.1990069251068414 1.0131716735432927 1.2156336251778241 1.295032571379297 1.1753967547040556 1.0 14.800638845616685 -6.370818895843049 5.624974123441464 1.157714506049352 1.3854751464439483 0.5782648218882512 0.09836371199959337 0.18746595609613237 8.193472931625795 0.03256374528742704 0.03698203764114838 4.2577592797273596e-07 6.370818895843049 0.2277606403945962 YVSGS(ph)SPDLVTR ddPTM_PC-9_AZD4547_30min_R2 5 YVSGSSPDLVTR 12 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 YVS(0.04)GS(0.596)S(0.364)PDLVTR;YVS(0.014)GS(0.493)S(0.493)PDLVTR;Y(0.105)VS(0.344)GS(0.498)S(0.052)PDLVTR;YVS(0.008)GS(0.496)S(0.496)PDLVTR;Y(0.007)VS(0.019)GS(0.693)S(0.281)PDLVTR 153.81 5.6618999999999994e-05 113127000.0 139197.0 151830.0 199869.0 224888.0 194033.0 192929.0 173843.0 205136.0 166110.0 169256.0 True False 183458.75052253684 200906.07830252592 197218.60646791547 173043.5460849644 167094.8672033765 180865.1191312093 189314.69022148463 173436.9447563289 174890.2354797139 163330.39895751685 1.1232370195229577 1.2300593128091404 1.2074825490337113 1.0594693161190036 1.0230481788441526 1.1073573583705831 1.1590903556828172 1.0618779226850528 1.0707757808465517 1.0 17.31743380387738 -1.5228787459948134 0.11737554832094277 0.9717684527251813 1.6546265208683977 0.41425228984753915 0.05531973992767947 106.1869706387196 0.8635980906200725 0.4560731328112888 11.819086766056468 0.029999999950645756 1.5228787459948134 0.6828580681432164 YVSGS(ph)SPDLVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 3 YVSGSSPDLVTR 12 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 Y(0.029)VS(0.017)GS(0.477)S(0.477)PDLVTR;YVS(0.005)GS(0.497)S(0.497)PDLVTR;YVS(0.008)GS(0.496)S(0.496)PDLVTR 148.89 0.00015469 35361400.0 81017.3 81210.0 80002.0 81862.0 98428.0 71802.4 82357.0 76961.0 68487.1 59287.9 True False 94731.92872538547 89271.99210180738 81909.55108927448 77275.53754018497 79141.73997130986 68036.95574309888 74555.54874695448 74940.85529691998 69488.59427263631 70036.32694724175 1.3526113212182997 1.2746526837287717 1.16952950932131 1.1033636529567936 1.130009859468033 0.9714523692019288 1.0645268248164563 1.0700283490505265 0.9921793061047014 1.0 16.095815803213092 -4.525593066283892 0.5077825840893201 1.0161219056831474 1.6986183249887834 0.9019553700127989 0.036879364521502846 1.6105398469125132 0.2634265509251534 0.02234301059304744 0.6922198522899043 2.9813086057894162e-05 4.525593066283892 0.682496419305636 YVSGS(ph)SPDLVTR ddPTM_PC-9_Lapatinib_30min_R1 5 YVSGSSPDLVTR 12 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 YVS(0.001)GS(0.499)S(0.499)PDLVTR;YVSGS(0.62)S(0.38)PDLVTR;YVS(0.001)GS(0.5)S(0.5)PDLVTR;YVSGS(0.5)S(0.5)PDLVTR;YVS(0.006)GS(0.71)S(0.285)PDLVTR 212.68 2.7e-09 108058000.0 230061.0 257099.0 354817.0 256282.0 297371.0 274434.0 243341.0 233378.0 323310.0 208292.0 True False 226780.28795197964 256503.70306161605 325645.31589322776 275129.8332116902 279880.2224338804 262697.09755690023 255940.0063033423 244221.59386827634 286895.42319476744 244294.99466835632 0.9283050938470768 1.0499752703072518 1.3330003602214975 1.126219690195429 1.1456649892226933 1.0753273840650144 1.047667827377285 0.9996995403029865 1.174381094398776 1.0 17.898264779134422 -6.909679806189996 4.886533345017234 1.0561188085878666 1.1252347457429883 0.0694194928060472 0.10414348253631954 0.5950949533321181 24.360505594504716 0.03934083525640012 0.03449394261710554 1.2311761498194746e-07 6.909679806189996 0.06911593715512176 YVSGSS(ph)PDLVTR ddPTM_PC-9_AZD4547_30min_R2 1 YVSGSSPDLVTR 12 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 YVS(0.019)GS(0.202)S(0.778)PDLVTR 159.66 0.00053679 18750000.0 24803.0 20078.0 31580.0 34014.0 25438.0 29395.0 24673.0 35301.0 24281.0 25847.0 True False 32689.8380655509 26567.820853310364 31161.228565994556 26172.59781106142 21906.37279184207 27556.926003150893 26868.849202065627 29846.04158628021 25564.444089356035 24942.104397214498 1.3106287081855714 1.0651796027394314 1.2493423998928737 1.049333985386748 0.878288874225406 1.1048356451522356 1.0772486865649678 1.1966128082445753 1.0249513706714755 1.0 14.606295571876057 -1.5228874399446723 0.837929387640026 1.0633207640382858 75.6257712386354 0.35564257511398667 0.0966335938474457 770.3628573353385 2.261899309418968 0.03458701596721615 109395.2985855178 0.029999399399877513 1.5228874399446723 74.56245047459711 YVSGSS(ph)PDLVTR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YVSGSSPDLVTR 12 0 Q15678 Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14 1 YVSGS(0.366)S(0.634)PDLVTR 143.76 8.8311e-05 16462000.0 28138.0 39072.0 39082.0 30026.0 46526.0 26230.0 36760.0 30505.0 31183.0 20050.0 True False 32901.207649167496 42950.809942147775 40013.86309931039 28343.740565605407 37409.56428968558 24854.45262472401 33277.826680647064 29704.276072719204 31638.992382559903 23684.906284287328 1.389121293293624 1.8134253700062783 1.6894245904555578 1.196700557958668 1.5794685375007478 1.0493793948938934 1.4050225186123586 1.254143703005705 1.3358293253433453 1.0 14.531680343068443 -5.757257582940865 24.999944249313366 1.281235248736094 1.6489339948086552 0.4523244772389128 0.18552007944214077 91.50418314739704 547027.9839852481 0.047888238544018476 0.07929815776858457 1.7488091506506664e-06 5.757257582940865 0.36769874607256114 YWGPAS(ph)PTHK ddPTM_PC-9_AZD4547_30min_R2 5 YWGPASPTHK 10 0 A0A3B3ISQ4;Q9H6S3;Q9H6S3-3;Q9H6S3-2 A0A3B3ISQ4 EPS8L2 Epidermal growth factor receptor kinase substrate 8-like protein 2 1 YWGPAS(0.996)PT(0.004)HK;YWGPAS(0.873)PT(0.127)HK;YWGPAS(0.842)PT(0.158)HK;Y(0.058)WGPAS(0.861)PT(0.081)HK;YWGPAS(0.964)PT(0.036)HK 95.273 0.0033891 554739000.0 464152.0 540600.0 558685.0 581023.0 576232.0 607255.0 592977.0 678801.0 553383.0 543437.0 True False 611742.6810386471 715338.3779908153 551276.471861706 447077.1240658655 496232.1332883389 569283.2488533219 645750.8042513389 573907.9027452071 582633.695626214 524411.4360393488 1.1665319232144766 1.3640785246665377 1.0512289282347789 0.8525312251815945 0.9462648965784654 1.0855660455326266 1.2313820025139297 1.0943847965629496 1.1110240082226135 1.0 19.0003396217382 -5.280543861962268 23.23994419562626 1.0474026282339082 1.2653051868965617 0.40702877755686495 0.10561134121178133 306.96724427724456 373415.37306422385 0.030754313404277245 0.06424182352602228 5.241506612671434e-06 5.280543861962268 0.2179025586626535 YWGPAS(ph)PTHK ddPTM_PC-9_LapatinibAZD4547_30min_R1 5 YWGPASPTHK 10 0 A0A3B3ISQ4;Q9H6S3;Q9H6S3-3;Q9H6S3-2 A0A3B3ISQ4 EPS8L2 Epidermal growth factor receptor kinase substrate 8-like protein 2 1 YWGPAS(0.741)PT(0.259)HK;Y(0.002)WGPAS(0.851)PT(0.147)HK;Y(0.001)WGPAS(0.982)PT(0.017)HK;YWGPAS(0.998)PT(0.002)HK;YWGPAS(0.999)PT(0.001)HK 112.02 0.00085632 325048500.0 309555.0 376135.0 369615.0 369780.0 468215.0 367152.0 530050.0 405717.0 374828.0 367145.0 True False 361956.54751005984 413475.1970103843 378428.0233726934 349062.4254429356 376471.6318595014 347897.90278584353 479839.8267703192 395067.3586426943 380309.15039509186 433705.48218177893 0.8345676095428118 0.9533547856724681 0.8725460915757641 0.8048374756227616 0.8680352158926847 0.8021524215827853 1.1063725188726206 0.9109116090838569 0.8768834290079205 1.0 18.72635615389902 -7.225301659483822 24.999933715265566 0.9661180267863194 0.8593297470151569 0.40793607268964704 0.06911793160194603 664.9280596882746 459995.3162166922 0.026817653634821022 0.020772175947890447 5.952485422707829e-08 7.225301659483822 -0.10678827977116256 YWGPAS(ph)PTHK ddPTM_PC-9_Lapatinib_30min_R1 3 YWGPASPTHK 10 0 A0A3B3ISQ4;Q9H6S3;Q9H6S3-3;Q9H6S3-2 A0A3B3ISQ4 EPS8L2 Epidermal growth factor receptor kinase substrate 8-like protein 2 1 YWGPAS(0.899)PT(0.101)HK;YWGPAS(0.987)PT(0.013)HK;YWGPAS(0.999)PT(0.001)HK 121.21 0.00036363 220165000.0 102451.0 173635.0 170852.0 158205.0 218481.0 227823.0 251908.0 251783.0 240216.0 193991.0 True False 100990.02995278772 173232.95882560252 156805.20806779183 169839.9234564087 205630.37713017268 218079.5413713519 264950.56364468945 263481.75735903205 213160.3444933784 227522.08587324063 0.44386912841970116 0.7613896389914243 0.6891867550614523 0.7464766455729119 0.9037820497335609 0.9584983388946713 1.1645048111606244 1.158049146515937 0.936877594433344 1.0 17.795647070883298 -6.218578346062923 0.9073938006106828 1.0806211979659361 0.5890805818471568 0.7871293871794918 0.09688894517074118 0.2709054115021482 0.47308848721538915 0.04754675820323862 0.08118937322868895 6.045352842629667e-07 6.218578346062923 -0.4915406161187793 YWLEEAECR ddPTM_PC-9_AZD4547_30min_R2 1 YWLEEAECR 9 0 P55884;P55884-2;C9JZG1;C9JQN7 P55884 EIF3B Eukaryotic translation initiation factor 3 subunit B 0 99.139 0.01013 0.0 29898.0 27561.0 31341.0 43021.0 37878.0 35662.0 34829.0 41603.0 34932.0 34217.0 False True 39404.94208296743 36469.55426526979 30925.397862154383 33103.17311782423 32619.29352187256 33432.04950244486 37928.71352728664 35174.21229183355 36778.43420490856 33019.07324484423 1.1933993964873113 1.104499632525705 0.9365919398414139 1.0025470088865422 0.9878924608208351 1.0125072031712796 1.1486910382383015 1.0652695195594515 1.1138542239567957 1.0 15.011012007861478 -7.227483734128526 24.678580473284 1.0873928807345805 1.0338110883426253 0.0665146037557568 0.07486074482187506 1360.9815461362546 989146.3434370264 0.030200586518219313 0.02339197949694666 5.922652688994756e-08 7.227483734128526 -0.05358179239195526 YWPTADGR ddPTM_PC-9_Lapatinib_30min_R1 2 YWPTADGR 8 0 P52788;P52788-2;H7C2R7 P52788 SMS Spermine synthase 0 ; 106.42 0.01763 7359900.0 20782.0 25769.0 22033.0 23782.0 20877.7 24310.0 20063.2 19285.8 30619.0 16339.0 False True 20485.64486904795 25709.333463742656 20221.531789839544 25531.007614426337 19649.71473313746 23270.317969377844 21101.97432600845 20181.888674274353 27170.36578763594 19163.174379650998 1.069011034560185 1.3416009766650612 1.0552287105059377 1.332295323761037 1.0253893401921506 1.214324803832508 1.1011732142048567 1.0531599971090964 1.4178426417956944 1.0 14.226048942839043 -6.272473902064554 24.870758780167456 1.140216414238139 1.1993741382292693 0.04645870538692587 0.1414872558084475 2701.2189944577526 6088277.889562449 0.041073409138243415 0.046998982202929085 5.33981361000928e-07 6.272473902064554 0.059157723991130284 YWS(ph)HY(ph)IDIER ddPTM_PC-9_AZD4547_30min_R2 1 YWSHYIDIER 10 0 Q8IU99 Q8IU99 CALHM1 Calcium homeostasis modulator protein 1 2 Y(0.419)WS(0.586)HY(0.996)IDIER 60.06399999999999 0.028481 0.0 0.0 0.0 0.0 0.0 0.0 380.7 0.0 0.0 0.0 0.0 True False 0.0 0.0 0.0 0.0 0.0 356.8947688178106 0.0 0.0 0.0 0.0 0.0 YY(ph)KQLNLVMNEQKEKIT(ph)EK ddPTM_PC-9_Lapatinib_30min_R1 1 YYKQLNLVMNEQKEKITEK 19 3 M0R2J8 M0R2J8 DCDC1 2 Y(0.098)Y(0.902)KQLNLVMNEQKEKIT(1)EK 52.853 0.023301 4353200.0 11070.0 10282.0 11187.0 7374.7 10773.0 9285.0 8331.0 8488.7 8419.5 6736.2 True False 10912.13977001062 10258.192660724202 10267.248043068796 7917.06003927802 10139.353320532919 8887.902194392153 8762.338416103934 8883.115991522916 7471.207248734469 7900.543194577702 1.3811885463141114 1.2984161225477004 1.299562294667968 1.0020905960885897 1.2833742023575994 1.1249735588423964 1.109080502479589 1.1243677520324897 0.9456574142727434 1.0 12.947736132531931 -1.5228787585657384 0.1983030151558616 0.9740419752150511 2.9155380736315544 0.6459989352426456 0.08503254520515958 33.81787577626036 0.40639253942265213 0.15719856059682735 20.346779237114657 0.029999999082277035 1.5228787585657384 1.9414960984165033 YYDSRPGGYGYGYGR ddPTM_PC-9_AZD4547_30min_R2 1 YYDSRPGGYGYGYGR 15 1 P98179 P98179 RBM3 RNA-binding protein 3 0 65.495 0.043802 14930000.0 49945.0 43681.0 70405.0 70486.0 67649.0 49276.0 56387.0 50903.0 49499.0 71362.0 False True 65826.47107946369 57800.02902148864 69471.38369819021 54236.54169784432 58257.104056738965 46194.76393030322 61405.33376390687 43037.11098457329 52115.41608578867 68863.63810090219 0.9558959255537981 0.8393403342529967 1.0088253483848404 0.7875933249180711 0.8459777273367108 0.6708150368503115 0.8916945932181645 0.6249613318644788 0.7567915016256729 1.0 16.07145478078087 -5.821093239507753 10.890446406936007 0.7818134165560953 0.9250649193915822 0.2459086761955721 0.10802396517727025 0.6472736543750278 115.29654301804116 0.028839688889285137 0.042833507002408955 1.5097559869850275e-06 5.821093239507753 0.14325150283548693 YYFEGIK ddPTM_PC-9_Lapatinib_30min_R1 1 YYFEGIK 7 0 O95433;G3V438;H0YJU2 O95433 AHSA1 Activator of 90 kDa heat shock protein ATPase homolog 1 0 123.96 0.021463 6124800.0 52018.0 35951.0 40100.0 34410.0 35852.0 38352.0 36336.0 29509.0 39188.0 33255.0 False True 51276.21378106711 35867.75766832284 36803.132790476346 36940.62618839501 33743.25584774398 36711.77436287859 38217.30028658656 30880.095867900825 34774.23477206562 39003.08244049786 1.3146708047830022 0.9196134106334237 0.9435954926542612 0.9471206857753028 0.8651433101273946 0.9412531540009732 0.979853331974208 0.7917347536572458 0.8915765779567891 1.0 15.25130052521382 -4.761370474227203 8.273194030078868 0.915620393910508 1.3189177282602298 0.8132823478305115 0.056702240851206114 0.036503477947226644 24.810803529057086 0.014141519327883958 0.08225167708894598 1.7323256096288934e-05 4.761370474227203 0.4032973343497218 YYGGGS(ph)EGGR ddPTM_PC-9_AZD4547_30min_R2 1 YYGGGSEGGR 10 0 P14866 P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 1 YYGGGS(1)EGGR 78.488 0.020327 9327200.0 4224.6 8902.3 15426.0 13033.0 14940.0 14528.0 11892.0 15878.0 10507.0 16185.0 True False 5567.934922861197 11779.794381035204 15221.441160830655 10028.44320784276 12865.838883171651 13619.561863370494 12950.364962143409 13424.419940142136 11062.378569534369 15618.368076330597 0.3564991486722175 0.7542269668293519 0.9745858905642338 0.6420928972112467 0.8237633291963222 0.8720220830248415 0.8291752953222746 0.8595276967820117 0.7082928584772719 1.0 13.930956097358301 -4.7779536609635676 3.9886413827774865 0.8290747585534418 0.3124248021120995 0.6667970738311607 0.1015554835966338 0.13146062582844645 3.9310227885233946 0.024065458823884427 0.19756885981147573 1.667425116610225e-05 4.7779536609635676 -0.5166499564413423 YYGGGS(ph)EGGR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YYGGGSEGGR 10 0 P14866 P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 1 YYGGGS(1)EGGR 97.59700000000001 0.0050839 6232000.0 18068.0 21040.0 25205.0 17567.0 25369.0 12277.0 15149.0 12179.0 10249.0 14580.0 True False 21126.555540733472 23128.712151484142 25805.982790494796 16582.777942982422 20398.126562890266 11633.172507576699 13713.977050737827 11859.314154717162 10398.872235796947 17223.23858478351 1.2266308358172828 1.342878230341536 1.4983234810028132 0.9628141572417788 1.184337455611381 0.6754346721907716 0.7962484513716215 0.6885647026451053 0.6037698534225848 1.0 14.072068826053098 -6.416892885564419 1.2650223587944924 0.7273105726798521 1.3368618569078368 0.6915901731413572 0.16223535051210852 0.23176690872798042 0.7648304152434592 0.06584422211041245 0.08168292064730227 3.829191748956257e-07 6.416892885564419 0.6095512842279847 YYGGGS(ph)EGGR ddPTM_PC-9_Lapatinib_30min_R1 1 YYGGGSEGGR 10 0 P14866 P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 1 YYGGGS(1)EGGR 84.81700000000001 0.012301000000000001 9659000.0 12193.0 19945.0 20658.0 20826.0 16876.0 21218.0 21108.0 17651.0 19346.0 10364.0 True False 12019.125584077647 19898.818577917136 18959.578982186056 22357.61351349939 15883.386859492568 20310.555601573797 22200.868957762785 18471.12989814353 17167.049757588575 12155.403590838054 0.9887886892654782 1.6370347910879373 1.5597654854073741 1.839314782633058 1.306693499791683 1.6709075473958397 1.826419731097727 1.5195817860022234 1.412297800669323 1.0 13.569310174918087 -8.69080236138525 2.291281384708648 1.0007994743164963 1.56217445695542 0.32094855883082163 0.2365890189157407 0.7535725779969568 7.437842717089661 0.22321171408373422 0.06086783115560538 2.0379693052258367e-09 8.69080236138525 0.5613749826389236 YYGGGS(ph)EGGRAPK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YYGGGSEGGRAPK 13 1 P14866 P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 1 Y(0.001)Y(0.001)GGGS(0.999)EGGRAPK 62.68 0.022874000000000002 6845300.0 23943.0 16970.0 18153.0 35025.0 29593.0 38065.0 26524.0 30147.0 35057.0 21832.0 True False 27996.07700419426 18654.669449177105 18585.83636563588 33062.66280258209 23794.464085127984 36068.80439039724 24011.4547028695 29355.673193386818 35569.64230367195 25789.9687779831 1.0855413298559133 0.7233304394343664 0.7206614527390437 1.2819970077206022 0.9226247728318818 1.398559443824887 0.9310385332210284 1.1382593537083985 1.3792045508034023 1.0 14.654522406112939 -5.758829311486723 24.999999773612608 1.1477305506871733 0.8311929890575286 0.3657001591758343 0.18509718665802996 69.37198914851615 664448.3281245537 0.048860031485664375 0.07992617306591832 1.7424915812801177e-06 5.758829311486723 -0.31653756162964475 YYGGGS(ph)EGGRAPK ddPTM_PC-9_Lapatinib_30min_R1 1 YYGGGSEGGRAPK 13 1 P14866 P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 1 Y(0.01)Y(0.01)GGGS(0.98)EGGRAPK 55.18600000000001 0.036976 9957800.0 112770.0 56174.0 80848.0 58689.0 55766.0 44432.0 33082.0 35156.0 61826.0 41631.0 True False 111161.87912051482 56043.93255432025 74200.9895223051 63005.184840764756 52485.95352017439 42531.74693605085 34794.82408853083 36789.476103287874 54862.50482335735 48826.86288017938 2.276654131831179 1.1478094075355914 1.5196755463154281 1.2903795395452464 1.07494011337518 0.8710726929236333 0.7126164171947105 0.7534679463960007 1.1236131421752278 1.0 15.57538746752689 -1.5228787452803954 0.47984770770519186 0.8784647900111805 34.907095398701316 0.748027455419662 0.2172771340817312 50.55771857136561 0.5668321225188375 0.12840440110656232 1715.8353453893212 0.02999999999999601 1.5228787452803954 34.028630608690136 up YYGGGSEGGR ddPTM_PC-9_Lapatinib_30min_R1 2 YYGGGSEGGR 10 0 P14866 P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 0 ; 113.41 0.0060397 21325500.0 44388.0 45123.0 35734.0 40938.0 40788.0 41653.0 43142.0 40529.0 37807.0 33989.0 False True 43755.01898023774 45018.52046584885 32796.08845722899 43948.71708516462 38388.93003229339 39871.59828788542 45375.68166457278 42412.12529838872 33548.777534640314 39863.953362504326 1.0976086235690141 1.129303961814105 0.8227003518440971 1.102467602385427 0.9629985687370805 1.0001917753944667 1.1382634645376828 1.0639217067286955 0.8415817977099078 1.0 15.282797170851827 YYLHDDR ddPTM_PC-9_AZD4547_30min_R2 3 YYLHDDR 7 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 0 ;; 87.75399999999999 0.01488 28209500.0 85937.0 101774.0 112508.0 95209.0 100117.0 123191.0 111169.0 143908.0 110707.0 99519.0 False True 113263.1783993569 134670.45520095664 111016.07040857882 73260.03601438658 86217.4826952141 115487.84729559981 121062.82563711051 121670.3252768596 116558.74600718005 96034.8701012259 1.1793963825844866 1.402307881074934 1.1559975068593515 0.7628482855984142 0.8977726799061243 1.2025616026123578 1.2606132075724559 1.2669390310895674 1.2137127470919769 1.0 16.551270720673124 -6.953635145516742 24.997487763333783 1.2109944964776995 1.0808227056751083 0.08268068696545905 0.17419921245874043 319.15325071948047 172069.56264477674 0.0692087672423593 0.06103636162310118 1.1126660949791857e-07 6.953635145516742 -0.13017179080259123 YYLHDDR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YYLHDDR 7 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 0 ;;; 102.72 0.0090534 25405700.0 116132.0 143099.0 141266.0 151290.0 162885.0 128921.0 143156.0 81230.0 111119.0 102961.0 False True 135790.8538884467 157304.92301165557 144634.31719428833 142813.7117887976 130968.85352975638 122160.1558075504 129595.2273203131 79097.79857029935 112743.90515850524 121627.01426117263 1.116453073466555 1.2933386876855408 1.1891627700710596 1.1741940115551162 1.0768072728359819 1.0043834139119203 1.0655135136510885 0.6503308418017294 0.9269643412968069 1.0 16.892104172068414 -6.898076300941357 1.0482344062878448 0.8613547534687956 1.207276812154186 0.5895906032450908 0.10697456254373133 0.32765328885849276 0.7564689831364942 0.062310731840440926 0.0493205109286126 1.2645141662062885e-07 6.898076300941357 0.3459220586853903 YYLHDDR ddPTM_PC-9_Lapatinib_30min_R1 3 YYLHDDR 7 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 0 ;; 83.75299999999999 0.017253 23579000.0 110455.0 110900.0 108701.0 85625.0 110090.0 109419.0 101692.0 110509.0 108065.0 90559.0 False True 108879.89144503363 110643.21786367596 99764.02337799448 91922.14813662673 103614.72264526757 104739.40443814686 106957.11417722257 115643.65157293908 95893.58172510125 106212.00248771756 1.0251185261065443 1.0417204767085606 0.939291426969671 0.8654591381727943 0.9755462680147627 0.9861352953048692 1.0070153247472307 1.088800219036565 0.9028507087623214 1.0 16.696587281549483 -6.965080599554052 3.066607354685953 1.00634549335354 0.9662349491809106 0.04606059419303454 0.06138196845858729 0.7645023850309972 14.75084890258207 0.02542990051923722 0.0210941609779916 1.0837257695830204e-07 6.965080599554052 -0.04011054417262949 YYNSDVHR ddPTM_PC-9_AZD4547_30min_R2 4 YYNSDVHR 8 0 K7EL89;P19623 K7EL89 SRM Spermidine synthase 0 ;;; 190.73 0.0025609 9052700.0 31385.1 27944.1 56082.0 90147.0 69010.0 56976.9 46069.5 70445.0 46234.7 58966.6 False True 41364.90894936585 36976.48384834093 55338.31603667215 69365.00190726627 59429.15269930892 53414.125435921975 50169.596251552786 59559.34391505938 48678.57185198919 56902.19728203617 0.7269474805048453 0.6498252372411335 0.9725163294202396 1.2190215004081146 1.0444087493624874 0.9387005772584573 0.8816811766140911 1.046696731584073 0.8554778932474871 1.0 15.796196742919465 -5.291418616531111 6.942404944250285 1.0008655869870409 0.6880792379437464 0.6137761577521379 0.09717922750541241 0.12062843351046273 21.774851019352045 0.02700846141528201 0.05865360612382762 5.111888629511235e-06 5.291418616531111 -0.3127863490432945 YYNSDVHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YYNSDVHR 8 0 K7EL89;P19623 K7EL89 SRM Spermidine synthase 0 ;;; 150.36 0.00048128 5156800.0 31969.5 34807.7 50606.2 51785.2 59230.8 54191.1 53559.8 50601.1 47806.4 36237.8 False True 37381.304923593045 38263.17841992467 51812.84373308226 48883.843133883645 47624.94993185547 51349.22331802066 48486.22800462789 49272.87474129717 48505.478159176826 42807.42628173304 0.8732434572817228 0.8938444037279693 1.2103704481573108 1.1419477268303693 1.1125394369289188 1.199540074660658 1.1326592653695262 1.151035673507031 1.1331089573090098 1.0 15.385573478289151 -5.250226391558939 24.267963133711874 1.142190245641397 0.8835438465382406 0.7737685874630138 0.05431260684350886 193.67559936134577 419163.6381149361 0.012753734366578501 0.033054755809677844 5.620482610183196e-06 5.250226391558939 -0.25864639910315645 YYNSDVHR ddPTM_PC-9_Lapatinib_30min_R1 4 YYNSDVHR 8 0 K7EL89;P19623 K7EL89 SRM Spermidine synthase 0 ;;; 170.24 0.00048128 9188100.0 59483.8 48456.8 63069.4 53056.2 67827.0 70584.8 52463.1 56240.8 70828.0 48788.1 False True 58635.550104007074 48344.60125677692 57884.07738692445 56958.12993829477 63837.54921301267 67566.05264520529 55179.38261408018 58853.95288513455 62850.60478809498 57221.058078943104 1.0247197810133555 0.8448742976769134 1.0115869809164773 0.9954050458087371 1.1156303528141922 1.1807899908455042 0.9643195087017407 1.0285366062951629 1.0983824294438118 1.0 15.804258554441073 -5.758896413796081 2.192316249445796 1.0647282222668342 0.9375671669851205 0.2949955545158046 0.07303941279252933 0.357423998544115 3.504381041558509 0.022172143458336437 0.04236571954518258 1.742222371834702e-06 5.758896413796081 -0.12716105528171362 YYPTEDVPR ddPTM_PC-9_AZD4547_30min_R2 2 YYPTEDVPR 9 0 Q02878;F8VZ45;U3KQR5;F8VR69 Q02878 RPL6 60S ribosomal protein L6 0 ; 110.12 0.010704 19918500.0 74705.0 70739.0 78064.0 115989.0 108864.0 101897.0 69925.0 89121.0 81856.0 87031.0 False True 98459.63603947003 93603.99837345952 77028.82035388848 89249.52806218635 93750.11272942433 95525.36448181886 76148.18953732582 75349.39724684501 86182.74104766386 83984.07118017485 1.1723608376669439 1.1145446637451832 0.9171836905671678 1.0626958994487807 1.1162844502774574 1.1374224080764548 0.9066980019813714 0.8971867663475674 1.0261796056870367 1.0 16.357828104958465 -7.265316416006803 24.98760389308252 0.9489483216235337 1.0805538438123203 0.42219635164335445 0.07357895334559225 355.87678865706283 2293620.238640691 0.03193408561414674 0.02240510874538654 5.4285467715082683e-08 7.265316416006803 0.13160552218878663 YYPTEDVPR ddPTM_PC-9_Lapatinib_30min_R1 3 YYPTEDVPR 9 0 Q02878;F8VZ45;U3KQR5;F8VR69 Q02878 RPL6 60S ribosomal protein L6 0 ;; 132.76 0.0054887 39581000.0 154785.0 136423.0 145253.0 149340.0 147660.0 162215.0 158677.0 130234.0 167165.0 127485.0 False True 152577.73751590704 136107.12092530387 133310.8590327947 160322.96178363572 138974.9291107296 155277.44259163408 166892.51864747613 136285.14708259175 148337.11737451135 149520.61238691513 1.0204461784913037 0.9102900178946491 0.8915885034487794 1.0722465566738537 0.9294700368876472 1.038501916978657 1.1161840229466666 0.9114806641503452 0.9920847367228456 1.0 17.189984857445765 -5.751817216075322 24.9998765480118 1.0073141888344261 0.9377264259773131 0.1851811095985263 0.0650344348762792 344.81833980785495 895882.8059628798 0.017857053730275196 0.030423969931275763 1.7708541106786718e-06 5.751817216075322 -0.06958776285711299 YYS(ph)DSDDELTVEQR ddPTM_PC-9_AZD4547_30min_R2 1 YYSDSDDELTVEQR 14 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 YYS(0.898)DS(0.059)DDELT(0.043)VEQR 82.515 0.042306 0.0 10758.0 9217.5 11695.0 9105.0 12728.0 9141.0 8549.0 14871.0 9271.3 13837.0 True False 14178.820219699097 12196.876616963245 11539.916658622747 7005.98292084772 10960.936901272338 8569.411824963501 9309.844438392542 12573.028651584184 9761.361990265914 13352.57084165501 1.061879422909819 0.9134478117812016 0.8642468027671899 0.5246916870114393 0.8208858826704989 0.6417799183832189 0.6972323568843628 0.941618569239195 0.7310473845092158 1.0 13.704829917974086 -5.112677797710968 2.082815106682749 0.7570241387471602 1.053860670128291 0.31408668939918616 0.13311622220821664 0.4470851708951765 3.2841859367872046 0.03585430222858658 0.19223956810681522 7.714756131610759e-06 5.112677797710968 0.29683653138113086 YYS(ph)DSDDELTVEQR ddPTM_PC-9_Lapatinib_30min_R1 1 YYSDSDDELTVEQR 14 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 YYS(0.969)DS(0.029)DDELT(0.002)VEQR 164.66 0.00051368 2610600.0 12737.0 13791.0 15298.0 12165.0 13338.0 13245.0 14010.0 13247.0 14514.0 11519.0 True False 12555.368044320263 13759.067786816517 14040.257491987719 13059.654681250364 12553.485063516939 12678.542225603025 14735.369248543528 13862.503980551097 12879.280480804331 13510.043801897296 0.9293358503069425 1.018432507589964 1.0392458897887482 0.9666626454176498 0.9291964739414078 0.938453080649709 1.090697370387071 1.0260887517333068 0.9533115265692638 1.0 13.72174473168733 -7.225291121301185 24.999827617549332 1.0196985803702616 0.9735234996473469 0.19802177975525337 0.046268386592105325 1079.3197376715318 746448.8966748263 0.018886697188322074 0.014629060205255656 5.952629861889551e-08 7.225291121301185 -0.04617508072291476 YYS(ph)IDDNQNK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YYSIDDNQNK 10 0 Q8NI08-2;Q8NI08;Q8NI08-4;Q8NI08-3;Q5TF97;Q5TF96 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 1 Y(0.002)YS(0.998)IDDNQNK 101.53 0.0035655 3904300.0 16424.0 17734.0 13378.0 20455.0 21211.0 14955.0 19435.0 20471.0 14707.0 13520.0 True False 19204.258811213567 19494.51432007699 13696.982256347523 19308.97266600476 17054.85681443752 14170.733473227123 17593.976102784967 19933.657940817393 14922.062052089539 15971.068975738892 1.202440415252486 1.2206142462780947 0.857612115829826 1.2089968865162604 1.0678594426174588 0.887275203353852 1.1016154353544763 1.2481104408914603 0.9343183023476472 1.0 13.963173258008345 YYS(ph)IDDNQNK ddPTM_PC-9_Lapatinib_30min_R1 2 YYSIDDNQNK 10 0 Q8NI08-2;Q8NI08;Q8NI08-4;Q8NI08-3;Q5TF97;Q5TF96 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 1 YYS(1)IDDNQNK;YYS(1)IDDNQNK 119.74 0.00076409 21067300.0 81796.0 94916.0 109439.0 105648.0 158122.0 95444.0 160872.0 132353.0 136800.0 122783.0 True False 80629.57404045077 94696.22783362151 100441.34786675657 113417.7063513966 148821.57483981314 91362.08261083094 169201.1650072585 138502.60355838173 121392.14343213664 144005.87795193616 0.5599047426894751 0.6575858512194038 0.6974808896361868 0.7875908120170708 1.033440974468308 0.6344330100284117 1.1749601295006278 0.9617843766391868 0.8429665869101042 1.0 17.135768174431057 -5.527445655154908 0.6489996334671849 0.9670731613535037 0.48371121858608696 0.5215275337601246 0.13248754065167248 1.2498705965940176 0.7417754233069578 0.07054174049468456 0.3948652791016975 2.9686181941935534e-06 5.527445655154908 -0.4833619427674168 YYS(ph)PCEEHPAETNQNEGAESGTIR ddPTM_PC-9_AZD4547_30min_R2 4 YYSPCEEHPAETNQNEGAESGTIR 24 0 A0A2R8YF49;A0A5F9ZH52;A5YM69 A0A2R8YF49;A0A5F9ZH52 ARHGEF35 Rho guanine nucleotide exchange factor 35 1 Y(0.002)Y(0.002)S(0.997)PCEEHPAETNQNEGAESGTIR;Y(0.003)Y(0.003)S(0.995)PCEEHPAETNQNEGAESGTIR;Y(0.002)Y(0.002)S(0.996)PCEEHPAETNQNEGAESGTIR;Y(0.003)Y(0.003)S(0.994)PCEEHPAETNQNEGAESGTIR 158.29 1.3088999999999999e-08 83235000.0 42579.9 48008.0 69485.0 91831.0 75211.0 78063.0 59248.0 77584.0 62741.1 64589.0 True False 56119.42248306052 63525.64715239184 68563.58349930757 70660.78172480682 64769.250886360256 73181.70826956845 64520.95722141548 65595.17550295923 66057.46645750583 62327.75876936152 0.9003921140614985 1.019219179490522 1.100048916455045 1.1336968169556831 1.039171825928047 1.1741431059693808 1.0351881488338077 1.0524231385519331 1.059840234299869 1.0 15.92758721566642 -4.840352976660368 2.729930192909361 1.0788569041229095 0.8785588854329333 0.5412861645238729 0.048448752219191746 0.28025230594930234 3.121389322319301 0.01222442009807487 0.12121681175249811 1.4442654541403964e-05 4.840352976660368 -0.2002980186899762 YYS(ph)PCEEHPAETNQNEGAESGTIR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YYSPCEEHPAETNQNEGAESGTIR 24 0 A0A2R8YF49;A0A5F9ZH52;A5YM69 A0A2R8YF49;A0A5F9ZH52 ARHGEF35 Rho guanine nucleotide exchange factor 35 1 Y(0.004)Y(0.004)S(0.992)PCEEHPAETNQNEGAESGTIR;Y(0.005)Y(0.005)S(0.989)PCEEHPAETNQNEGAESGTIR;Y(0.009)Y(0.009)S(0.982)PCEEHPAETNQNEGAESGTIR;Y(0.007)Y(0.007)S(0.986)PCEEHPAETNQNEGAESGTIR 162.35 7.6199e-09 69076000.0 58820.0 74061.6 75764.7 98973.0 109322.0 87983.0 84109.0 78585.5 79508.0 69358.0 True False 68777.06425204474 81413.94619193718 77571.21778722462 93427.86368479516 87901.13887454348 83369.01659478061 76141.58662357282 76522.71389322009 80670.65408564193 81932.05636237413 0.839440230181131 0.9936763436261697 0.94677494049628 1.140309029613228 1.0728540546543703 1.0175384372882208 0.9293259562143678 0.9339777040963152 0.9846042888127549 1.0 16.322140404145188 -4.509036331447946 1.9697793922351698 1.0058481476255987 0.6607157470652526 0.3844931427903615 0.0615467746778822 2.475487184077685 5.25990497459521 0.018425991699011393 2.0094100046322545 3.097160191570086e-05 4.509036331447946 -0.3451324005603461 YYS(ph)PCEEHPAETNQNEGAESGTIR ddPTM_PC-9_Lapatinib_30min_R1 5 YYSPCEEHPAETNQNEGAESGTIR 24 0 A0A2R8YF49;A0A5F9ZH52;A5YM69 A0A2R8YF49;A0A5F9ZH52 ARHGEF35 Rho guanine nucleotide exchange factor 35 1 Y(0.002)Y(0.002)S(0.996)PCEEHPAETNQNEGAESGTIR;Y(0.003)Y(0.003)S(0.994)PCEEHPAETNQNEGAESGTIR;Y(0.008)Y(0.008)S(0.984)PCEEHPAETNQNEGAESGTIR;Y(0.003)Y(0.003)S(0.995)PCEEHPAETNQNEGAESGTIR;Y(0.004)Y(0.004)S(0.992)PCEEHPAETNQNEGAESGTIR 157.61 2.8445e-09 68351500.0 67511.9 77079.9 93516.0 69493.2 80729.0 81087.0 77561.8 81440.3 89108.0 64613.3 True False 66549.16792583381 76901.42622732488 85827.47546219933 74603.96175051948 75980.67893932063 77619.0980330293 81577.57049119801 85224.31365043232 79071.71869116115 75781.6228131897 0.8781702668189763 1.0147767146250697 1.1325631766130664 0.9844598067585161 1.002626707092584 1.0242469763991355 1.076482232272803 1.124603967119046 1.0434154845968648 1.0 16.209560414084287 -7.15789573898105 4.059296812723396 1.0714213422450434 1.0098183660110456 0.14178972966197556 0.06472535351928559 0.46231276099754187 13.355198018953885 0.026568241587403906 0.020139975113556877 6.951911920149472e-08 7.15789573898105 -0.0616029762339978 YYTSASGDEMVS(ph)LKDYCTR ddPTM_PC-9_Lapatinib_30min_R1 1 YYTSASGDEMVSLKDYCTR 19 1 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 YYTS(0.001)AS(0.001)GDEMVS(0.963)LKDY(0.023)CT(0.012)R 50.18899999999999 0.02862 4748200.0 14957.0 12107.0 13811.0 12327.0 14404.0 12502.0 11576.0 9255.1 12227.0 13629.0 True False 14743.710437222133 12078.966985351864 12675.512892001714 13233.568701666522 13556.78503935357 11967.318603585421 12175.348638196992 9685.125733403675 10849.866503981993 15984.754490499025 0.9223607685676661 0.7556554586141019 0.7929751376247757 0.8278868911957488 0.8481071790881377 0.7486707794416564 0.7616850571858169 0.6058976845193521 0.678763412377144 1.0 13.964408965515892 -6.8694373361314245 4.97263136012813 0.7322472386110784 0.8229974290823473 0.07562474855582779 0.10364900569515778 0.4181798613645115 16.601218281877347 0.03587754469272056 0.031681050148699104 1.3507117064876587e-07 6.8694373361314245 0.09075019047126887 YYTSASGDEMVSLK ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YYTSASGDEMVSLK 14 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 98.75399999999999 0.013484999999999999 0.0 6233.3 10178.0 8322.5 10752.0 9025.7 9601.6 8949.0 7747.2 8117.8 7428.0 False True 7288.474576713193 11188.404575941333 8520.939963257008 10149.60029845432 7257.178876529578 9098.075193349227 8101.28593485067 7543.844208836912 8236.507467631232 8774.637599984359 0.8306296976556826 1.2750845204092847 0.9710873943411858 1.156697377276574 0.8270630887983925 1.0368605073063581 0.9232615982755927 0.8597328519699047 0.9386720960015391 1.0 13.09912382677422 -6.258252632671241 24.991249446459122 0.9288312701223608 1.0676192026279478 0.20640801957009525 0.12184159049772579 402.81319792869937 3158956.4802750507 0.034062774955356416 0.04215185974216168 5.517563846838062e-07 6.258252632671241 0.13878793250558707 YYTSASGDEMVSLK ddPTM_PC-9_Lapatinib_30min_R1 3 YYTSASGDEMVSLK 14 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 ;; 174.77 0.0012231 17091800.0 60167.0 53158.0 65489.0 56300.0 63660.0 61848.0 74964.0 54517.0 61609.0 63218.0 False True 59309.007546723544 53034.915917017766 60104.74721485052 60440.48981129438 59915.6439603755 59202.905214729784 78845.26911833088 57050.05884409327 54669.94564846865 74145.14706731006 0.7999041055631322 0.7152850593022884 0.8106362937049211 0.8151644740339595 0.8080858468860166 0.7984730971129441 1.0633908251170368 0.7694375303120295 0.7373368023511838 1.0 16.178064648344737 -7.039137732653897 24.999721860698294 0.8815569184307672 0.7897434723634532 0.21659322591142682 0.09355693775686609 980.3584771650126 626213.4961757616 0.03627506161468533 0.028104119010042748 9.138233845056425e-08 7.039137732653897 -0.09181344606731401 YYTVFDR ddPTM_PC-9_Lapatinib_30min_R1 1 YYTVFDR 7 0 H7C1V0;H7C469;A0A1B0GW44;A0A1B0GV23;A0A1B0GVD5;A0A1B0GWE8;P07339;A0A1B0GVP3 H7C1V0 CTSD Cathepsin D;Cathepsin D light chain;Cathepsin D heavy chain 0 110.34 0.043677999999999995 7721600.0 33278.0 31138.0 37558.0 34228.0 35800.0 35100.0 31228.0 32671.0 43402.0 34832.0 False True 32803.44961756221 31065.901874113 34470.126218072575 36745.24130126082 33694.31438550807 33598.85482209636 32844.83304022249 34189.01393134936 38513.609716678344 40852.66478927744 0.8029696419258334 0.7604375879604024 0.8437668973584292 0.899457636137002 0.8247764144470641 0.8224397354591912 0.8039826339270588 0.8368857725120274 0.9427441249019078 1.0 15.3181425669262 -8.373119112240467 2.6082633640039563 0.9982825959625624 0.8234015460546541 0.7668750271861668 0.033229350222214515 0.13568526088806568 1.770672677991943 0.034909446328325114 0.00961083060162243 4.2352679109061255e-09 8.373119112240467 -0.17488104990790831 YYTVFDRDNNR ddPTM_PC-9_AZD4547_30min_R2 2 YYTVFDRDNNR 11 1 H7C1V0;H7C469;A0A1B0GW44;A0A1B0GV23;A0A1B0GVD5;A0A1B0GWE8;P07339;A0A1B0GVP3 H7C1V0 CTSD Cathepsin D;Cathepsin D light chain;Cathepsin D heavy chain 0 ; 80.24 0.021243 53172100.0 90324.0 66990.0 115309.0 208964.0 141541.0 111009.0 76310.0 116861.0 85490.0 112334.0 False True 119045.15314408846 88643.20743915025 113779.92731843781 160790.5782616171 121890.4753255019 104067.58968136676 83101.44216794167 98802.81764862996 90008.82686870592 108401.22085180861 1.0981901514451649 0.8177325563549803 1.0496185045183415 1.4832912120189872 1.124438215434252 0.9600223029188371 0.7666098362632525 0.9114548422263594 0.830330379689669 1.0 16.726021479347523 -6.910819933843889 4.082077730185759 0.8687365398067908 1.114073152042327 0.3272965201649455 0.161329250113523 0.28964277481786516 9.093558234255395 0.06491366924357997 0.05652094727945093 1.2279482546418036e-07 6.910819933843889 0.24533661223553627 YYTVFDRDNNR ddPTM_PC-9_LapatinibAZD4547_30min_R1 1 YYTVFDRDNNR 11 1 H7C1V0;H7C469;A0A1B0GW44;A0A1B0GV23;A0A1B0GVD5;A0A1B0GWE8;P07339;A0A1B0GVP3 H7C1V0 CTSD Cathepsin D;Cathepsin D light chain;Cathepsin D heavy chain 0 90.149 0.01153 15284000.0 63645.0 38698.0 50189.0 71840.0 69800.0 70399.0 67537.0 66560.0 68623.0 56920.0 False True 74418.84145395087 42539.681693827675 51385.696102842456 67815.03770842259 56123.191063492486 66707.1525096434 61139.40643446309 64812.87052614952 69626.48155303858 67239.1454215279 1.10677851402502 0.6326624383332479 0.7642229207510175 1.0085648364993989 0.8346803147430184 0.9920880476908298 0.9092829192158076 0.9639157386643175 1.0355051527877739 1.0 16.037013768252642 -6.790813786110379 0.7479200097490402 0.9988583190918133 0.8361758328930773 0.15048289569172757 0.12488603841345924 1.1928505735391655 1.4573895710604228 0.08855957398058792 0.08478646955016184 1.6187739759635974e-07 6.790813786110379 -0.16268248619873604 YYTVFDRDNNR ddPTM_PC-9_Lapatinib_30min_R1 2 YYTVFDRDNNR 11 1 H7C1V0;H7C469;A0A1B0GW44;A0A1B0GV23;A0A1B0GVD5;A0A1B0GWE8;P07339;A0A1B0GVP3 H7C1V0 CTSD Cathepsin D;Cathepsin D light chain;Cathepsin D heavy chain 0 ; 94.40899999999999 0.0086137 26577200.0 134812.0 90606.0 100374.0 94778.0 94179.0 112117.0 78692.0 80030.0 102927.0 69700.0 False True 132889.55615850727 90396.20737381619 92121.63717484467 101748.29029013975 88639.57638303812 107322.01726749209 82766.28671708681 83748.48596387872 91334.27739063985 81747.552130588 1.6256089961718028 1.105797115850177 1.1269039227949547 1.2446646735990514 1.0843086315470392 1.3128468617145874 1.012461958308812 1.024476987764653 1.1172723220474847 1.0 16.318887910381143 -4.760348065290436 24.997880513747752 1.1216206104442987 1.625609594955782 0.7239367314227918 0.09462599660998106 14.55891485397184 333337.5926129989 0.023537662337644 0.14041183112108716 1.7364086263283485e-05 4.760348065290436 0.5039889845114833 YYVGHK ddPTM_PC-9_AZD4547_30min_R2 2 YYVGHK 6 0 F5H124;F5H6N1;P61326-2;P61326;Q96A72 F5H124 MAGOHB;MAGOH Protein mago nashi homolog;Protein mago nashi homolog 2 0 ; 105.82 0.028213 4328400.0 55726.0 53955.0 64429.0 75320.0 76794.0 66391.0 62854.0 59931.0 64797.0 65209.0 False True 73445.70882719393 71394.8986024684 63574.629362839274 57956.13768239979 66132.47866092925 62239.56027471304 68447.88423566785 50670.04102737487 68222.03713430268 62926.05275807484 1.167174891925335 1.13458409471436 1.010306964704396 0.9210197548099457 1.0509554590239725 0.9890904887042401 1.087751117948272 0.8052315186871905 1.0841620305756148 1.0 15.941369827545142 -5.251380038922235 3.549152395030884 0.9878970178605103 1.1591514680955373 0.39570902075615144 0.078345687054796 0.21418845623151886 5.848949575242859 0.019771592453285875 0.05505738901211616 5.605572334309186e-06 5.251380038922235 0.17125445023502694 YYVT(ph)IIDAPGHR ddPTM_PC-9_Lapatinib_30min_R1 1 YYVTIIDAPGHR 12 0 Q5VTE0;P68104;A0A087WVQ9;A0A087WV01;A6PW80;Q5JR01 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 1 YYVT(1)IIDAPGHR 98.25299999999999 0.0077932 4163200.0 29090.0 33904.0 44330.0 41060.0 27921.0 37338.0 33715.0 28437.0 42266.0 28225.0 True False 28675.17126554735 33825.49737105555 40685.35851874856 44079.68937214468 26278.741674798042 35741.140779129164 35460.59773123804 29758.28683437241 37505.557999288685 33103.653642551566 0.8662237581137622 1.0218055606882053 1.2290292472868143 1.3315656890357408 0.7938320633290835 1.0796735963062205 1.0711989109763054 0.8989426712742364 1.1329733691715194 1.0 15.01470283528572 -6.26518762082939 24.994206003845235 0.9989838639910548 1.1140505336055653 0.13194339371609687 0.14568314573563362 748.9720766767132 4994326.09768003 0.046377155323906745 0.05464441496922254 5.430156910152876e-07 6.26518762082939 0.11506666961451051 YYVTIIDAPGHR ddPTM_PC-9_AZD4547_30min_R2 2 YYVTIIDAPGHR 12 0 Q5VTE0;P68104;A0A087WVQ9;A0A087WV01;A6PW80;Q5JR01 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 0 ; 122.18 0.00034643 104108000.0 333666.0 288566.0 384743.0 497040.0 463330.0 393950.0 396680.0 532200.0 383574.0 446750.0 False True 439764.8473160549 381839.31628430885 379641.0564333895 382455.1071914496 399004.62715795956 369316.24422321067 431983.75152901525 449960.7187393647 403848.93855815916 431109.41848011746 1.0200771044772168 0.8857132317602546 0.8806141553850054 0.8871416183385663 0.9255298308365801 0.8566647546816316 1.0020281000864706 1.0437274145522215 0.9367666797490403 1.0 18.717694555965345 -7.281532652711632 24.317778983847266 0.9992745195697278 0.9066464066807521 0.4350591659866295 0.048071806272436034 526.312588587032 636963.7409991798 0.019691772047756302 0.013297555898157962 5.229586457198486e-08 7.281532652711632 -0.09262811288897566 YYVTIIDAPGHR ddPTM_PC-9_LapatinibAZD4547_30min_R1 4 YYVTIIDAPGHR 12 0 Q5VTE0;P68104;A0A087WVQ9;A0A087WV01;A6PW80;Q5JR01 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 0 ;;; 119.39 0.00045419 91749500.0 244501.0 226540.0 260629.0 267050.0 313100.0 273160.0 289894.0 279689.0 258665.0 203751.6 False True 285890.19018512685 249029.3940492977 266843.38380098675 252088.05428778127 251750.30260715607 258835.00872930305 262433.14166919235 272347.4601049912 262447.4862788973 240690.1521832223 1.1877934663795326 1.0346472084147724 1.1086593339217952 1.047355082878017 1.0459518194808168 1.0753867841350992 1.090336016196535 1.131527225499738 1.0903956140220998 1.0 17.876817589713816 -4.748846113525237 24.994091148908634 1.0741247990360823 1.1877937324233985 0.47767480498953807 0.036851205495235476 557.4881795166087 1106390.9122380412 0.009082958239869066 0.15923353314531155 1.7830104415697477e-05 4.748846113525237 0.1136689333873162 YYVTIIDAPGHR ddPTM_PC-9_Lapatinib_30min_R1 2 YYVTIIDAPGHR 12 0 Q5VTE0;P68104;A0A087WVQ9;A0A087WV01;A6PW80;Q5JR01 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 0 ; 150.09 0.00014281 151222000.0 337040.0 320480.0 363540.0 336320.0 340040.0 334260.0 290250.0 286640.0 362760.0 288200.0 False True 332233.74779443385 319737.9482502319 333651.1445049811 361054.0947306309 320039.5157443617 319964.47899811744 305277.72479584307 299958.34083076636 321902.1487678503 338014.98599763954 0.982896503283301 0.9459283212149202 0.9870897987561744 1.0681600215593763 0.9468204931795439 0.9465985008142563 0.9031484917594006 0.8874113671186787 0.952330997449025 1.0 18.36672768468747 -6.503531087581672 23.97988970620166 0.9306914778665608 0.9937639157667801 0.3167652935212901 0.040177638871015636 522.5345028710416 647641.0530789229 0.012931609808762097 0.014433498021679838 3.1366705935883106e-07 6.503531087581672 0.06307243790021932